PSIBLAST 2.11.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: uniprot_sprot.fasta
           571,864 sequences; 207,016,062 total letters

Results from round 1


Query= YP_009725304.1 nsp8 [Severe acute respiratory syndrome coronavirus
2]

Length=198
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute resp...  405     7e-130
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re...  404     2e-129
sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respi...  397     4e-127
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res...  396     9e-127
sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus H...  394     5e-126
sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus 2...  394     9e-126
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus...  393     1e-125
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus...  392     3e-125
sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus R...  390     1e-124
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus...  389     3e-124
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus...  237     4e-71 
sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus H...  237     4e-71 
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res...  217     4e-64 
sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respi...  215     2e-63 
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus...  207     7e-61 
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus...  207     1e-60 
sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus 1...  207     1e-60 
sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus H...  206     2e-60 
sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus H...  206     2e-60 
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus...  206     4e-60 
sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus...  202     5e-59 
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir...  202     5e-59 
sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus...  200     4e-58 
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir...  200     4e-58 
sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus...  189     1e-54 
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir...  189     2e-54 
sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronaviru...  187     9e-54 
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi...  187     1e-53 
sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic ...  186     3e-53 
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi...  186     3e-53 
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi...  186     4e-53 
sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus...  185     4e-53 
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir...  185     4e-53 
sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronaviru...  185     4e-53 
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir...  185     5e-53 
sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus...  185     5e-53 
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi...  185     7e-53 
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi...  185     7e-53 
sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronaviru...  184     8e-53 
sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronaviru...  184     8e-53 
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus...  184     1e-52 
sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus 5...  184     1e-52 
sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus...  182     8e-52 
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir...  181     9e-52 
sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus...  181     1e-51 
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir...  181     1e-51 
sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus...  181     1e-51 
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir...  181     1e-51 
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir...  181     2e-51 
sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus...  181     2e-51 
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi...  175     2e-49 
sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmiss...  175     2e-49 
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir...  174     3e-49 
sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious ...  158     2e-43 
sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious b...  158     2e-43 
sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious b...  157     2e-43 
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou...  157     2e-43 
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious...  157     2e-43 
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious...  157     3e-43 
sp|B2A4X5|GLSA_NATTJ Glutaminase OS=Natranaerobius thermophilus (...  32.7    1.8   
sp|P31759|FRZF_MYXXA Protein methyltransferase FrzF OS=Myxococcus...  31.6    5.4   
sp|Q8D219|SYM_WIGBR Methionine--tRNA ligase OS=Wigglesworthia glo...  30.8    8.2   
sp|Q8SSA8|CHK1_ENCCU Probable serine/threonine-protein kinase CHK...  30.8    9.0   


>sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute 
respiratory syndrome coronavirus 2 OX=2697049 PE=1 SV=1
Length=4405

 Score = 405 bits (1041),  Expect = 7e-130, Method: Compositional matrix adjust.
 Identities = 198/198 (100%), Positives = 198/198 (100%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE
Sbjct  3943  AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  4002

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  4003  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4062

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL
Sbjct  4063  PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  4122

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4123  AWPLIVTALRANSAVKLQ  4140


>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute 
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1 
SV=1
Length=7096

 Score = 404 bits (1038),  Expect = 2e-129, Method: Compositional matrix adjust.
 Identities = 198/198 (100%), Positives = 198/198 (100%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE
Sbjct  3943  AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  4002

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  4003  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4062

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL
Sbjct  4063  PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  4122

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4123  AWPLIVTALRANSAVKLQ  4140


>sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respiratory 
syndrome coronavirus OX=694009 GN=1a PE=1 SV=1
Length=4382

 Score = 397 bits (1021),  Expect = 4e-127, Method: Compositional matrix adjust.
 Identities = 193/198 (97%), Positives = 196/198 (99%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE
Sbjct  3920  AIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  3979

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3980  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4039

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNL
Sbjct  4040  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNL  4099

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4100  AWPLIVTALRANSAVKLQ  4117


>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute 
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073

 Score = 396 bits (1018),  Expect = 9e-127, Method: Compositional matrix adjust.
 Identities = 193/198 (97%), Positives = 196/198 (99%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE
Sbjct  3920  AIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  3979

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3980  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4039

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNL
Sbjct  4040  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNL  4099

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4100  AWPLIVTALRANSAVKLQ  4117


>sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus 
HKU3 OX=442736 GN=1a PE=3 SV=1
Length=4376

 Score = 394 bits (1013),  Expect = 5e-126, Method: Compositional matrix adjust.
 Identities = 191/198 (96%), Positives = 195/198 (98%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAV+NGDSEVVLKKLKKSLNVAKSEFD DAAMQRKLE
Sbjct  3914  AIASEFSSLPSYAAYATAQEAYEQAVSNGDSEVVLKKLKKSLNVAKSEFDHDAAMQRKLE  3973

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3974  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4033

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNL
Sbjct  4034  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNL  4093

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4094  AWPLIVTALRANSAVKLQ  4111


>sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus 
279/2005 OX=389167 GN=1a PE=3 SV=1
Length=4388

 Score = 394 bits (1011),  Expect = 9e-126, Method: Compositional matrix adjust.
 Identities = 192/198 (97%), Positives = 195/198 (98%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE
Sbjct  3926  AIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  3985

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3986  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4045

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNS NL
Sbjct  4046  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSQNL  4105

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4106  AWPLIVTALRANSAVKLQ  4123


>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus 
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067

 Score = 393 bits (1010),  Expect = 1e-125, Method: Compositional matrix adjust.
 Identities = 191/198 (96%), Positives = 195/198 (98%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAV+NGDSEVVLKKLKKSLNVAKSEFD DAAMQRKLE
Sbjct  3914  AIASEFSSLPSYAAYATAQEAYEQAVSNGDSEVVLKKLKKSLNVAKSEFDHDAAMQRKLE  3973

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3974  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4033

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNL
Sbjct  4034  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNL  4093

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4094  AWPLIVTALRANSAVKLQ  4111


>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus 
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079

 Score = 392 bits (1007),  Expect = 3e-125, Method: Compositional matrix adjust.
 Identities = 192/198 (97%), Positives = 195/198 (98%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE
Sbjct  3926  AIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  3985

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3986  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4045

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNS NL
Sbjct  4046  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSQNL  4105

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4106  AWPLIVTALRANSAVKLQ  4123


>sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus 
Rp3/2004 OX=349344 GN=1a PE=3 SV=1
Length=4380

 Score = 390 bits (1002),  Expect = 1e-124, Method: Compositional matrix adjust.
 Identities = 190/198 (96%), Positives = 195/198 (98%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR+AAMQRKLE
Sbjct  3918  AIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRNAAMQRKLE  3977

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3978  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4037

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+M+NS NL
Sbjct  4038  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMENSSNL  4097

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4098  AWPLIVTALRANSAVKLQ  4115


>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus 
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071

 Score = 389 bits (1000),  Expect = 3e-124, Method: Compositional matrix adjust.
 Identities = 190/198 (96%), Positives = 195/198 (98%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR+AAMQRKLE
Sbjct  3918  AIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRNAAMQRKLE  3977

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3978  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4037

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+M+NS NL
Sbjct  4038  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMENSSNL  4097

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4098  AWPLIVTALRANSAVKLQ  4115


>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus 
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930

 Score = 237 bits (605),  Expect = 4e-71, Method: Composition-based stats.
 Identities = 114/200 (57%), Positives = 150/200 (75%), Gaps = 2/200 (1%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             A+ASEFS+L SY  +  AQ+AY+ AVA G     +  LKK++NVAKS  D+D A  RKLE
Sbjct  3783  AVASEFSNLSSYVDYENAQKAYDTAVATGAPASTVNALKKAMNVAKSVLDKDVATTRKLE  3842

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +M++ AMT MYKQAR+ED+R+KVT+AMQTMLF M+R+LD+DAL+NI+NNAR+G VPL +I
Sbjct  3843  RMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILNNARNGVVPLGVI  3902

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P T A KL++V+PD++ Y  T    T TYA + W++ QV DAD K V  ++I+ +NS NL
Sbjct  3903  PRTAANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGKTVNATDITRENSVNL  3962

Query  181   AWPLIVTALR--ANSAVKLQ  198
             AWPL+VTA R  A S VKLQ
Sbjct  3963  AWPLVVTAQRQQATSPVKLQ  3982


>sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus 
HKU9 OX=694006 GN=1a PE=3 SV=1
Length=4248

 Score = 237 bits (604),  Expect = 4e-71, Method: Composition-based stats.
 Identities = 114/200 (57%), Positives = 150/200 (75%), Gaps = 2/200 (1%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             A+ASEFS+L SY  +  AQ+AY+ AVA G     +  LKK++NVAKS  D+D A  RKLE
Sbjct  3783  AVASEFSNLSSYVDYENAQKAYDTAVATGAPASTVNALKKAMNVAKSVLDKDVATTRKLE  3842

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +M++ AMT MYKQAR+ED+R+KVT+AMQTMLF M+R+LD+DAL+NI+NNAR+G VPL +I
Sbjct  3843  RMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILNNARNGVVPLGVI  3902

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P T A KL++V+PD++ Y  T    T TYA + W++ QV DAD K V  ++I+ +NS NL
Sbjct  3903  PRTAANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGKTVNATDITRENSVNL  3962

Query  181   AWPLIVTALR--ANSAVKLQ  198
             AWPL+VTA R  A S VKLQ
Sbjct  3963  AWPLVVTAQRQQATSPVKLQ  3982


>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East 
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) 
OX=1263720 GN=rep PE=1 SV=1
Length=7078

 Score = 217 bits (552),  Expect = 4e-64, Method: Composition-based stats.
 Identities = 106/200 (53%), Positives = 151/200 (76%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  SEFS L ++A    AQ+AY++A+ +GD S  VLK L+K++N+AK+ +++D A+ RKL
Sbjct  3929  ATLSEFSHLATFAELEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKNAYEKDKAVARKL  3988

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MADQAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN II+NAR+GC+PL++
Sbjct  3989  ERMADQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIPLSV  4048

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IPL  + KL VVIPD+  +       +  YA ALW+I  + + D++IV+ S++ +D++ N
Sbjct  4049  IPLCASNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDV-VDSNEN  4107

Query  180   LAWPLIVTALRAN-SAVKLQ  198
             L WPL++   RA+ SAVKLQ
Sbjct  4108  LTWPLVLECTRASTSAVKLQ  4127


>sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respiratory 
syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) 
OX=1263720 GN=1a PE=1 SV=1
Length=4391

 Score = 215 bits (547),  Expect = 2e-63, Method: Compositional matrix adjust.
 Identities = 106/200 (53%), Positives = 151/200 (76%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  SEFS L ++A    AQ+AY++A+ +GD S  VLK L+K++N+AK+ +++D A+ RKL
Sbjct  3929  ATLSEFSHLATFAELEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKNAYEKDKAVARKL  3988

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MADQAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN II+NAR+GC+PL++
Sbjct  3989  ERMADQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIPLSV  4048

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IPL  + KL VVIPD+  +       +  YA ALW+I  + + D++IV+ S++ +D++ N
Sbjct  4049  IPLCASNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDV-VDSNEN  4107

Query  180   LAWPLIVTALRAN-SAVKLQ  198
             L WPL++   RA+ SAVKLQ
Sbjct  4108  LTWPLVLECTRASTSAVKLQ  4127


>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus 
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126

 Score = 207 bits (528),  Expect = 7e-61, Method: Composition-based stats.
 Identities = 100/200 (50%), Positives = 151/200 (76%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  +EFS L +YA   TAQ +Y++A+ +GD S  VLK L+K++NVAK+ +++D A+ RKL
Sbjct  3980  ATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKL  4039

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GCVPL+I
Sbjct  4040  ERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSI  4099

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             +PL  + KL VVIPD + +    +  + +YA +LW++  + + D+++V+ +++ ++ + +
Sbjct  4100  VPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDVTVINNVDNEVVKPTDV-VETNES  4158

Query  180   LAWPLIVTALRA-NSAVKLQ  198
             L WPL++   RA +SAVKLQ
Sbjct  4159  LTWPLVIECSRASSSAVKLQ  4178


>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus 
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119

 Score = 207 bits (527),  Expect = 1e-60, Method: Composition-based stats.
 Identities = 100/200 (50%), Positives = 151/200 (76%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  +EFS L +YA   TAQ +Y++A+ +GD S  VLK L+K++NVAK+ +++D A+ RKL
Sbjct  3973  ATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKL  4032

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GCVPL+I
Sbjct  4033  ERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSI  4092

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             +PL  + KL VVIPD + +    +  + +YA +LW+I  + + D+++V+ +++ ++ + +
Sbjct  4093  VPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVVKPTDV-VETNES  4151

Query  180   LAWPLIVTALR-ANSAVKLQ  198
             L WPL++   R ++SAVKLQ
Sbjct  4152  LTWPLVIECSRSSSSAVKLQ  4171


>sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus 
133/2005 OX=389230 GN=1a PE=3 SV=1
Length=4441

 Score = 207 bits (526),  Expect = 1e-60, Method: Composition-based stats.
 Identities = 100/200 (50%), Positives = 151/200 (76%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  +EFS L +YA   TAQ +Y++A+ +GD S  VLK L+K++NVAK+ +++D A+ RKL
Sbjct  3980  ATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKL  4039

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GCVPL+I
Sbjct  4040  ERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSI  4099

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             +PL  + KL VVIPD + +    +  + +YA +LW++  + + D+++V+ +++ ++ + +
Sbjct  4100  VPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDVTVINNVDNEVVKPTDV-VETNES  4158

Query  180   LAWPLIVTALRA-NSAVKLQ  198
             L WPL++   RA +SAVKLQ
Sbjct  4159  LTWPLVIECSRASSSAVKLQ  4178


>sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus 
HKU4 OX=694007 GN=1a PE=1 SV=1
Length=4434

 Score = 206 bits (525),  Expect = 2e-60, Method: Composition-based stats.
 Identities = 100/200 (50%), Positives = 151/200 (76%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  +EFS L +YA   TAQ +Y++A+ +GD S  VLK L+K++NVAK+ +++D A+ RKL
Sbjct  3973  ATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKL  4032

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GCVPL+I
Sbjct  4033  ERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSI  4092

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             +PL  + KL VVIPD + +    +  + +YA +LW+I  + + D+++V+ +++ ++ + +
Sbjct  4093  VPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVVKPTDV-VETNES  4151

Query  180   LAWPLIVTALR-ANSAVKLQ  198
             L WPL++   R ++SAVKLQ
Sbjct  4152  LTWPLVIECSRSSSSAVKLQ  4171


>sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus 
HKU5 OX=694008 GN=1a PE=3 SV=1
Length=4481

 Score = 206 bits (524),  Expect = 2e-60, Method: Compositional matrix adjust.
 Identities = 102/200 (51%), Positives = 146/200 (73%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  SEFS L SYA    AQ +Y++A+ +GD S  VLK L+K++N+AK+ +++D A+ RKL
Sbjct  4020  ATLSEFSHLASYAELEAAQSSYQKALNSGDASPQVLKALQKAVNIAKNAYEKDKAVARKL  4079

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I+NAR+GCVPL++
Sbjct  4080  ERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVISNARNGCVPLSV  4139

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             +PL  + KL VVIPD   +       + +YA ALW+I  + + D ++V+ S+++  N  +
Sbjct  4140  VPLCASNKLRVVIPDITIWNKVVTWPSLSYAGALWDISLINNVDGEVVKSSDVTETNE-S  4198

Query  180   LAWPLIVTALR-ANSAVKLQ  198
             L WPL++   R A+SAV LQ
Sbjct  4199  LTWPLVLECTRAASSAVTLQ  4218


>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus 
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182

 Score = 206 bits (523),  Expect = 4e-60, Method: Compositional matrix adjust.
 Identities = 102/200 (51%), Positives = 146/200 (73%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  SEFS L SYA    AQ +Y++A+ +GD S  VLK L+K++N+AK+ +++D A+ RKL
Sbjct  4020  ATLSEFSHLASYAELEAAQSSYQKALNSGDASPQVLKALQKAVNIAKNAYEKDKAVARKL  4079

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I+NAR+GCVPL++
Sbjct  4080  ERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVISNARNGCVPLSV  4139

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             +PL  + KL VVIPD   +       + +YA ALW+I  + + D ++V+ S+++  N  +
Sbjct  4140  VPLCASNKLRVVIPDITIWNKVVTWPSLSYAGALWDISLINNVDGEVVKSSDVTETNE-S  4198

Query  180   LAWPLIVTALR-ANSAVKLQ  198
             L WPL++   R A+SAV LQ
Sbjct  4199  LTWPLVLECTRAASSAVTLQ  4218


>sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus 
NL63 OX=277944 GN=1a PE=1 SV=1
Length=4060

 Score = 202 bits (514),  Expect = 5e-59, Method: Composition-based stats.
 Identities = 95/199 (48%), Positives = 142/199 (71%), Gaps = 5/199 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS F S+PSY A+  A++AYE A+ANG S  ++K+LK+++N+AKSEFD + ++Q+K+ 
Sbjct  3605  SVASSFVSMPSYIAYENARQAYEDAIANGSSSQLIKQLKRAMNIAKSEFDHEISVQKKIN  3664

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA TQMYK+ARS ++++KV SAM ++LF MLR+LD  ++  ++N ARDG VPL++I
Sbjct  3665  RMAEQAATQMYKEARSVNRKSKVISAMHSLLFGMLRRLDMSSVETVLNLARDGVVPLSVI  3724

Query  121   PLTTAAKLMVVIPDYNTY-KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             P T+A+KL +V PD  +Y K  CDG+   YA  +W +  V D D + V + EI+ +N   
Sbjct  3725  PATSASKLTIVSPDLESYSKIVCDGSVH-YAGVVWTLNDVKDNDGRPVHVKEITKENVET  3783

Query  180   LAWPLIVTALRANSAVKLQ  198
             L WPLI+   R    VKLQ
Sbjct  3784  LTWPLILNCER---VVKLQ  3799


>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus 
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729

 Score = 202 bits (514),  Expect = 5e-59, Method: Composition-based stats.
 Identities = 95/199 (48%), Positives = 142/199 (71%), Gaps = 5/199 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS F S+PSY A+  A++AYE A+ANG S  ++K+LK+++N+AKSEFD + ++Q+K+ 
Sbjct  3605  SVASSFVSMPSYIAYENARQAYEDAIANGSSSQLIKQLKRAMNIAKSEFDHEISVQKKIN  3664

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA TQMYK+ARS ++++KV SAM ++LF MLR+LD  ++  ++N ARDG VPL++I
Sbjct  3665  RMAEQAATQMYKEARSVNRKSKVISAMHSLLFGMLRRLDMSSVETVLNLARDGVVPLSVI  3724

Query  121   PLTTAAKLMVVIPDYNTY-KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             P T+A+KL +V PD  +Y K  CDG+   YA  +W +  V D D + V + EI+ +N   
Sbjct  3725  PATSASKLTIVSPDLESYSKIVCDGSVH-YAGVVWTLNDVKDNDGRPVHVKEITKENVET  3783

Query  180   LAWPLIVTALRANSAVKLQ  198
             L WPLI+   R    VKLQ
Sbjct  3784  LTWPLILNCER---VVKLQ  3799


>sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus 
229E OX=11137 GN=1a PE=1 SV=1
Length=4085

 Score = 200 bits (508),  Expect = 4e-58, Method: Composition-based stats.
 Identities = 94/199 (47%), Positives = 147/199 (74%), Gaps = 5/199 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS F  +PS+ A+ TA++ YE AVANG S  ++K+LKK++NVAK+EFDR++++Q+K+ 
Sbjct  3630  SVASSFVGMPSFVAYETARQEYENAVANGSSPQIIKQLKKAMNVAKAEFDRESSVQKKIN  3689

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA   MYK+AR+ ++++KV SAM ++LF MLR+LD  +++ I+N AR+G VPL++I
Sbjct  3690  RMAEQAAAAMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNMARNGVVPLSVI  3749

Query  121   PLTTAAKLMVVIPDYNTY-KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             P T+AA+L+VV+PD++++ K   DG    YA  +W +Q+V D D K V L +++ +N   
Sbjct  3750  PATSAARLVVVVPDHDSFVKMMVDGFVH-YAGVVWTLQEVKDNDGKNVHLKDVTKENQEI  3808

Query  180   LAWPLIVTALRANSAVKLQ  198
             L WPLI+T  R    VKLQ
Sbjct  3809  LVWPLILTCER---VVKLQ  3824


>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus 
229E OX=11137 GN=rep PE=1 SV=1
Length=6758

 Score = 200 bits (508),  Expect = 4e-58, Method: Composition-based stats.
 Identities = 94/199 (47%), Positives = 147/199 (74%), Gaps = 5/199 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS F  +PS+ A+ TA++ YE AVANG S  ++K+LKK++NVAK+EFDR++++Q+K+ 
Sbjct  3630  SVASSFVGMPSFVAYETARQEYENAVANGSSPQIIKQLKKAMNVAKAEFDRESSVQKKIN  3689

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA   MYK+AR+ ++++KV SAM ++LF MLR+LD  +++ I+N AR+G VPL++I
Sbjct  3690  RMAEQAAAAMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNMARNGVVPLSVI  3749

Query  121   PLTTAAKLMVVIPDYNTY-KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             P T+AA+L+VV+PD++++ K   DG    YA  +W +Q+V D D K V L +++ +N   
Sbjct  3750  PATSAARLVVVVPDHDSFVKMMVDGFVH-YAGVVWTLQEVKDNDGKNVHLKDVTKENQEI  3808

Query  180   LAWPLIVTALRANSAVKLQ  198
             L WPLI+T  R    VKLQ
Sbjct  3809  LVWPLILTCER---VVKLQ  3824


>sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus 
(strain 2) OX=76344 GN=1a PE=3 SV=1
Length=4416

 Score = 189 bits (481),  Expect = 1e-54, Method: Composition-based stats.
 Identities = 93/201 (46%), Positives = 138/201 (69%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A A+G + +  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  3959  ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL  4018

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4019  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKLDNQALNSILDNAVKGCVPLNA  4078

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP  T+  L +++PD   +    D    TYA  +W IQ + DAD  + QL+EI +    N
Sbjct  4079  IPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQLNEIDV----N  4134

Query  180   LAWPLIVTALRAN--SAVKLQ  198
             + WPL++ A R N  S+V LQ
Sbjct  4135  ITWPLVIAANRHNEVSSVVLQ  4155


>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus 
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124

 Score = 189 bits (481),  Expect = 2e-54, Method: Composition-based stats.
 Identities = 93/201 (46%), Positives = 138/201 (69%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A A+G + +  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  3959  ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL  4018

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4019  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKLDNQALNSILDNAVKGCVPLNA  4078

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP  T+  L +++PD   +    D    TYA  +W IQ + DAD  + QL+EI +    N
Sbjct  4079  IPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQLNEIDV----N  4134

Query  180   LAWPLIVTALRAN--SAVKLQ  198
             + WPL++ A R N  S+V LQ
Sbjct  4135  ITWPLVIAANRHNEVSSVVLQ  4155


>sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronavirus 
(strain JHM) OX=11144 GN=1a PE=1 SV=1
Length=4474

 Score = 187 bits (475),  Expect = 9e-54, Method: Composition-based stats.
 Identities = 92/201 (46%), Positives = 139/201 (69%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A A+G + +  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  4017  ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL  4076

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4077  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4136

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP  T+  L +++PD   +    D    TYA  +W IQ + DAD  + QL+EI ++++  
Sbjct  4137  IPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDVNST--  4194

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL+++A R N  S V LQ
Sbjct  4195  --WPLVISANRHNEVSTVVLQ  4213


>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus 
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180

 Score = 187 bits (475),  Expect = 1e-53, Method: Composition-based stats.
 Identities = 92/201 (46%), Positives = 139/201 (69%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A A+G + +  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  4017  ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL  4076

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4077  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4136

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP  T+  L +++PD   +    D    TYA  +W IQ + DAD  + QL+EI ++++  
Sbjct  4137  IPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDVNST--  4194

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL+++A R N  S V LQ
Sbjct  4195  --WPLVISANRHNEVSTVVLQ  4213


>sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic 
diarrhea virus (strain CV777) OX=229032 GN=1a PE=1 SV=1
Length=4117

 Score = 186 bits (472),  Expect = 3e-53, Method: Composition-based stats.
 Identities = 86/198 (43%), Positives = 134/198 (68%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS +  LPSY  +  A++ YE AV NG    ++K+L+ ++NVAKSEFDR+A+ QRKL+
Sbjct  3663  SVASTYVGLPSYVIYENARQQYEDAVNNGSPPQLVKQLRHAMNVAKSEFDREASTQRKLD  3722

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA  QMYK+AR+ ++++KV SAM ++LF MLR+LD  +++ I+N A+DG VPL++I
Sbjct  3723  RMAEQAAAQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNLAKDGVVPLSVI  3782

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A KL +V  D ++Y          YA  +W I  + D D K+V + E++  N+ +L
Sbjct  3783  PAVSATKLNIVTSDIDSYNRIQREGCVHYAGTIWNIIDIKDNDGKVVHVKEVTAQNAESL  3842

Query  181   AWPLIVTALRANSAVKLQ  198
             +WPL++   R    VKLQ
Sbjct  3843  SWPLVLGCER---IVKLQ  3857


>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic 
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781

 Score = 186 bits (471),  Expect = 3e-53, Method: Composition-based stats.
 Identities = 86/198 (43%), Positives = 134/198 (68%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS +  LPSY  +  A++ YE AV NG    ++K+L+ ++NVAKSEFDR+A+ QRKL+
Sbjct  3663  SVASTYVGLPSYVIYENARQQYEDAVNNGSPPQLVKQLRHAMNVAKSEFDREASTQRKLD  3722

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA  QMYK+AR+ ++++KV SAM ++LF MLR+LD  +++ I+N A+DG VPL++I
Sbjct  3723  RMAEQAAAQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNLAKDGVVPLSVI  3782

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A KL +V  D ++Y          YA  +W I  + D D K+V + E++  N+ +L
Sbjct  3783  PAVSATKLNIVTSDIDSYNRIQREGCVHYAGTIWNIIDIKDNDGKVVHVKEVTAQNAESL  3842

Query  181   AWPLIVTALRANSAVKLQ  198
             +WPL++   R    VKLQ
Sbjct  3843  SWPLVLGCER---IVKLQ  3857


>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus 
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176

 Score = 186 bits (471),  Expect = 4e-53, Method: Composition-based stats.
 Identities = 92/201 (46%), Positives = 138/201 (69%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A A+G + +  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  4011  ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL  4070

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4071  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4130

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP  T+  L +++PD   +    D    TYA  +W IQ + DAD  + QL+EI ++++  
Sbjct  4131  IPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDVNST--  4188

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  S V LQ
Sbjct  4189  --WPLVIAANRHNEVSTVVLQ  4207


>sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus 
(strain Mebus) OX=11132 GN=1a PE=3 SV=1
Length=4383

 Score = 185 bits (470),  Expect = 4e-53, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLHEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATALQ  4122


>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus 
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094

 Score = 185 bits (470),  Expect = 4e-53, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLHEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATALQ  4122


>sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronavirus 
(strain A59) OX=11142 GN=1a PE=1 SV=1
Length=4468

 Score = 185 bits (470),  Expect = 4e-53, Method: Composition-based stats.
 Identities = 92/201 (46%), Positives = 138/201 (69%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A A+G + +  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  4011  ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL  4070

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4071  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4130

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP  T+  L +++PD   +    D    TYA  +W IQ + DAD  + QL+EI ++++  
Sbjct  4131  IPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDVNST--  4188

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  S V LQ
Sbjct  4189  --WPLVIAANRHNEVSTVVLQ  4207


>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus 
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059

 Score = 185 bits (470),  Expect = 5e-53, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLHEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATVLQ  4122


>sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus 
(strain Quebec) OX=11133 GN=1a PE=3 SV=1
Length=4383

 Score = 185 bits (470),  Expect = 5e-53, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLHEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATVLQ  4122


>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus 
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094

 Score = 185 bits (469),  Expect = 7e-53, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 137/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL+EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATVLQ  4122


>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus 
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094

 Score = 185 bits (469),  Expect = 7e-53, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 137/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL+EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATVLQ  4122


>sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronavirus 
(strain 98TXSF-110-LUN) OX=233264 GN=1a PE=3 SV=1
Length=4383

 Score = 184 bits (468),  Expect = 8e-53, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 137/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL+EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATVLQ  4122


>sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronavirus 
(strain 98TXSF-110-ENT) OX=233262 GN=1a PE=3 SV=1
Length=4383

 Score = 184 bits (468),  Expect = 8e-53, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 137/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL+EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATVLQ  4122


>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus 
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793

 Score = 184 bits (468),  Expect = 1e-52, Method: Composition-based stats.
 Identities = 86/198 (43%), Positives = 135/198 (68%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++A+ + +LPSY A+ TA+++YE A+ANG    ++K+L+ ++NVAKSEFDR+A+ QRKL+
Sbjct  3674  SVAATYVNLPSYLAYETARQSYEDALANGSPPQLVKQLRHAMNVAKSEFDREASTQRKLD  3733

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA +QMYK+AR+ ++++KV SAM ++LF MLR+LD  +++ I++ A+DG VPL+II
Sbjct  3734  RMAEQAASQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLAKDGVVPLSII  3793

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A KL +V+ D  +Y          YA  +W +  + D D K V   E+   N  +L
Sbjct  3794  PAVSATKLNIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAKEVVTSNVESL  3853

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPL +   R    +KLQ
Sbjct  3854  AWPLFLNCER---IIKLQ  3868


>sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus 
512/2005 OX=693999 GN=1a PE=3 SV=1
Length=4128

 Score = 184 bits (467),  Expect = 1e-52, Method: Composition-based stats.
 Identities = 86/198 (43%), Positives = 135/198 (68%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++A+ + +LPSY A+ TA+++YE A+ANG    ++K+L+ ++NVAKSEFDR+A+ QRKL+
Sbjct  3674  SVAATYVNLPSYLAYETARQSYEDALANGSPPQLVKQLRHAMNVAKSEFDREASTQRKLD  3733

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA +QMYK+AR+ ++++KV SAM ++LF MLR+LD  +++ I++ A+DG VPL+II
Sbjct  3734  RMAEQAASQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLAKDGVVPLSII  3793

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A KL +V+ D  +Y          YA  +W +  + D D K V   E+   N  +L
Sbjct  3794  PAVSATKLNIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAKEVVTSNVESL  3853

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPL +   R    +KLQ
Sbjct  3854  AWPLFLNCER---IIKLQ  3868


>sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus 
HKU1 (isolate N1) OX=443239 GN=1a PE=1 SV=1
Length=4471

 Score = 182 bits (461),  Expect = 8e-52, Method: Composition-based stats.
 Identities = 90/193 (47%), Positives = 131/193 (68%), Gaps = 5/193 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++    A  +G  ++  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  4014  ALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNIAKSVYERDKAVARKL  4073

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPL+ 
Sbjct  4074  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLSA  4133

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +VIPD   +    D    TYA ++W IQ V DAD    QL++IS+D++  
Sbjct  4134  IPALAANTLTIVIPDKQVFDKVVDNVYVTYAGSVWHIQTVQDADGINKQLTDISVDSN--  4191

Query  180   LAWPLIVTALRAN  192
               WPL++ A R N
Sbjct  4192  --WPLVIIANRYN  4202


>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus 
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182

 Score = 181 bits (460),  Expect = 9e-52, Method: Composition-based stats.
 Identities = 90/193 (47%), Positives = 131/193 (68%), Gaps = 5/193 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++    A  +G  ++  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  4014  ALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNIAKSVYERDKAVARKL  4073

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPL+ 
Sbjct  4074  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLSA  4133

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +VIPD   +    D    TYA ++W IQ V DAD    QL++IS+D++  
Sbjct  4134  IPALAANTLTIVIPDKQVFDKVVDNVYVTYAGSVWHIQTVQDADGINKQLTDISVDSN--  4191

Query  180   LAWPLIVTALRAN  192
               WPL++ A R N
Sbjct  4192  --WPLVIIANRYN  4202


>sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus 
HKU1 (isolate N2) OX=443240 GN=1a PE=3 SV=1
Length=4441

 Score = 181 bits (460),  Expect = 1e-51, Method: Composition-based stats.
 Identities = 89/193 (46%), Positives = 130/193 (67%), Gaps = 5/193 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++    A  +G  ++  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  3984  ALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNIAKSVYERDKAVARKL  4043

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4044  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4103

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L ++IPD   +    D     YA ++W IQ V DAD    QL++IS+D++  
Sbjct  4104  IPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQTVQDADGINKQLTDISVDSN--  4161

Query  180   LAWPLIVTALRAN  192
               WPL++ A R N
Sbjct  4162  --WPLVIIANRYN  4172


>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus 
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152

 Score = 181 bits (460),  Expect = 1e-51, Method: Composition-based stats.
 Identities = 89/193 (46%), Positives = 130/193 (67%), Gaps = 5/193 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++    A  +G  ++  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  3984  ALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNIAKSVYERDKAVARKL  4043

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4044  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4103

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L ++IPD   +    D     YA ++W IQ V DAD    QL++IS+D++  
Sbjct  4104  IPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQTVQDADGINKQLTDISVDSN--  4161

Query  180   LAWPLIVTALRAN  192
               WPL++ A R N
Sbjct  4162  --WPLVIIANRYN  4172


>sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus 
HKU1 (isolate N5) OX=443241 GN=1a PE=3 SV=1
Length=4421

 Score = 181 bits (460),  Expect = 1e-51, Method: Composition-based stats.
 Identities = 89/193 (46%), Positives = 131/193 (68%), Gaps = 5/193 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++    A  +G  ++  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  3964  ALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNIAKSVYERDKAVARKL  4023

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPL+ 
Sbjct  4024  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLSA  4083

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L ++IPD   +    D    TYA ++W IQ V DAD    QL++IS+D++  
Sbjct  4084  IPALAANTLTIIIPDKQVFDKVVDNVYVTYAGSVWHIQTVQDADGINKQLTDISVDSN--  4141

Query  180   LAWPLIVTALRAN  192
               WPL++ A R N
Sbjct  4142  --WPLVIIANRYN  4152


>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus 
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132

 Score = 181 bits (459),  Expect = 1e-51, Method: Composition-based stats.
 Identities = 89/193 (46%), Positives = 131/193 (68%), Gaps = 5/193 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++    A  +G  ++  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  3964  ALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNIAKSVYERDKAVARKL  4023

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPL+ 
Sbjct  4024  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLSA  4083

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L ++IPD   +    D    TYA ++W IQ V DAD    QL++IS+D++  
Sbjct  4084  IPALAANTLTIIIPDKQVFDKVVDNVYVTYAGSVWHIQTVQDADGINKQLTDISVDSN--  4141

Query  180   LAWPLIVTALRAN  192
               WPL++ A R N
Sbjct  4142  --WPLVIIANRYN  4152


>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus 
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095

 Score = 181 bits (459),  Expect = 2e-51, Method: Composition-based stats.
 Identities = 93/201 (46%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A  +G + +  LK+L+K+ N+AKS ++RD A+ +KL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAYERDRAVAKKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL+EIS D +  
Sbjct  4046  IPSLAANTLNIIVPDKSVYDQIVDNIYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRYNEVSATVLQ  4122


>sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus 
OC43 OX=31631 GN=1a PE=1 SV=1
Length=4383

 Score = 181 bits (458),  Expect = 2e-51, Method: Composition-based stats.
 Identities = 93/201 (46%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A  +G + +  LK+L+K+ N+AKS ++RD A+ +KL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAYERDRAVAKKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL+EIS D +  
Sbjct  4046  IPSLAANTLNIIVPDKSVYDQIVDNIYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRYNEVSATVLQ  4122


>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible 
gastroenteritis coronavirus (strain Purdue) OX=11151 
GN=rep PE=1 SV=1
Length=6684

 Score = 175 bits (444),  Expect = 2e-49, Method: Composition-based stats.
 Identities = 84/198 (42%), Positives = 130/198 (66%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS +++LPS+ A   A+   E+A  N  S  +LK+L K+ N+AKS+F+R+A++Q+KL+
Sbjct  3558  SVASAYAALPSWIALEKARADLEEAKKNDVSPQILKQLTKAFNIAKSDFEREASVQKKLD  3617

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMA+QA   MYK+AR+ D+++K+ SAM ++LF ML+KLD  ++N II+ AR+G +PL+II
Sbjct  3618  KMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSII  3677

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A +L+V+ P    +          YA A+W I +V DA+   V L E++  N  NL
Sbjct  3678  PAASATRLVVITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAANELNL  3737

Query  181   AWPLIVTALRANSAVKLQ  198
              WPL +T  R     KLQ
Sbjct  3738  TWPLSITCER---TTKLQ  3752


>sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmissible 
gastroenteritis coronavirus (strain Purdue) OX=11151 
GN=1a PE=1 SV=1
Length=4017

 Score = 175 bits (443),  Expect = 2e-49, Method: Composition-based stats.
 Identities = 84/198 (42%), Positives = 130/198 (66%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS +++LPS+ A   A+   E+A  N  S  +LK+L K+ N+AKS+F+R+A++Q+KL+
Sbjct  3558  SVASAYAALPSWIALEKARADLEEAKKNDVSPQILKQLTKAFNIAKSDFEREASVQKKLD  3617

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMA+QA   MYK+AR+ D+++K+ SAM ++LF ML+KLD  ++N II+ AR+G +PL+II
Sbjct  3618  KMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSII  3677

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A +L+V+ P    +          YA A+W I +V DA+   V L E++  N  NL
Sbjct  3678  PAASATRLVVITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAANELNL  3737

Query  181   AWPLIVTALRANSAVKLQ  198
              WPL +T  R     KLQ
Sbjct  3738  TWPLSITCER---TTKLQ  3752


>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus 
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709

 Score = 174 bits (441),  Expect = 3e-49, Method: Composition-based stats.
 Identities = 85/198 (43%), Positives = 130/198 (66%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS +++LPS+ A+  A+   E+A  N  S  +LK+L K+ N+AKSEF+R+A++Q+KL+
Sbjct  3583  SVASAYAALPSWIAYEKARADLEEAKKNDVSPQLLKQLTKACNIAKSEFEREASVQKKLD  3642

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMA+QA   MYK+AR+ D+++K+ SAM ++LF ML+KLD  ++N II  AR+G +PL+II
Sbjct  3643  KMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIEQARNGVLPLSII  3702

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A +L+VV P+              YA A+W I +V DA+   V L E++  N  N+
Sbjct  3703  PAASATRLIVVTPNLEVLSKVRQENNVHYAGAIWSIVEVKDANGAQVHLKEVTAANELNI  3762

Query  181   AWPLIVTALRANSAVKLQ  198
              WPL +T  R     KLQ
Sbjct  3763  TWPLSITCER---TTKLQ  3777


>sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious 
bronchitis virus (strain Beaudette CK) OX=160235 GN=1a PE=3 
SV=1
Length=3951

 Score = 158 bits (399),  Expect = 2e-43, Method: Composition-based stats.
 Identities = 77/199 (39%), Positives = 122/199 (61%), Gaps = 9/199 (5%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQ  56
             ++  EFS +PSYA +  A+  YE+ + +    G ++  L   +K+ N+AKS FDRD A+Q
Sbjct  3463  SVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQ  3522

Query  57    RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP  116
             +KL+ MA++AMT MYK+AR  D+RAK+ S++  +LF+ML+K+D++ LN + + A  G VP
Sbjct  3523  KKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVP  3582

Query  117   LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-  175
             L  +P+  + KL +VIPD  T+    +G   TY++ +W I  V+DAD   +  +      
Sbjct  3583  LATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGL  3642

Query  176   ----NSPNLAWPLIVTALR  190
                 +  N+AWPL V   R
Sbjct  3643  TYCISGANIAWPLKVNLTR  3661


>sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious 
bronchitis virus (strain Beaudette) OX=11122 GN=1a PE=1 SV=1
Length=3951

 Score = 158 bits (399),  Expect = 2e-43, Method: Composition-based stats.
 Identities = 77/199 (39%), Positives = 122/199 (61%), Gaps = 9/199 (5%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQ  56
             ++  EFS +PSYA +  A+  YE+ + +    G ++  L   +K+ N+AKS FDRD A+Q
Sbjct  3463  SVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQ  3522

Query  57    RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP  116
             +KL+ MA++AMT MYK+AR  D+RAK+ S++  +LF+ML+K+D++ LN + + A  G VP
Sbjct  3523  KKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVP  3582

Query  117   LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-  175
             L  +P+  + KL +VIPD  T+    +G   TY++ +W I  V+DAD   +  +      
Sbjct  3583  LATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGL  3642

Query  176   ----NSPNLAWPLIVTALR  190
                 +  N+AWPL V   R
Sbjct  3643  TYCISGANIAWPLKVNLTR  3661


>sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious 
bronchitis virus (strain M41) OX=11127 GN=1a PE=1 SV=1
Length=3953

 Score = 157 bits (398),  Expect = 2e-43, Method: Composition-based stats.
 Identities = 81/202 (40%), Positives = 124/202 (61%), Gaps = 15/202 (7%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQ  56
             ++  EFS +PSYA +  A+  YE+ +A+    G ++  L   +K+ N+AKS FDRD A+Q
Sbjct  3465  SVTQEFSHIPSYAEYERAKSIYEKVLADSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQ  3524

Query  57    RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP  116
             +KL+ MA++AMT MYK+AR  D+RAK+ S++  +LF+ML+K+D++ LN + + A  G VP
Sbjct  3525  KKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQANSGVVP  3584

Query  117   LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSE-----  171
             L  +P+  + KL +VIPD  T+    +G   TY++ +W I  V DAD   +  +      
Sbjct  3585  LATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDCVTDADGTELHPTSTGSGL  3644

Query  172   ---ISMDNSPNLAWPLIVTALR  190
                IS D   N+AWPL V   R
Sbjct  3645  TYCISGD---NIAWPLKVNLTR  3663


>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious 
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep 
PE=3 SV=1
Length=6629

 Score = 157 bits (398),  Expect = 2e-43, Method: Composition-based stats.
 Identities = 77/199 (39%), Positives = 122/199 (61%), Gaps = 9/199 (5%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQ  56
             ++  EFS +PSYA +  A+  YE+ + +    G ++  L   +K+ N+AKS FDRD A+Q
Sbjct  3463  SVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQ  3522

Query  57    RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP  116
             +KL+ MA++AMT MYK+AR  D+RAK+ S++  +LF+ML+K+D++ LN + + A  G VP
Sbjct  3523  KKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVP  3582

Query  117   LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-  175
             L  +P+  + KL +VIPD  T+    +G   TY++ +W I  V+DAD   +  +      
Sbjct  3583  LATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGL  3642

Query  176   ----NSPNLAWPLIVTALR  190
                 +  N+AWPL V   R
Sbjct  3643  TYCISGANIAWPLKVNLTR  3661


>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious 
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1 
SV=1
Length=6629

 Score = 157 bits (398),  Expect = 2e-43, Method: Composition-based stats.
 Identities = 77/199 (39%), Positives = 122/199 (61%), Gaps = 9/199 (5%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQ  56
             ++  EFS +PSYA +  A+  YE+ + +    G ++  L   +K+ N+AKS FDRD A+Q
Sbjct  3463  SVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQ  3522

Query  57    RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP  116
             +KL+ MA++AMT MYK+AR  D+RAK+ S++  +LF+ML+K+D++ LN + + A  G VP
Sbjct  3523  KKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVP  3582

Query  117   LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-  175
             L  +P+  + KL +VIPD  T+    +G   TY++ +W I  V+DAD   +  +      
Sbjct  3583  LATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGL  3642

Query  176   ----NSPNLAWPLIVTALR  190
                 +  N+AWPL V   R
Sbjct  3643  TYCISGANIAWPLKVNLTR  3661


>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious 
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631

 Score = 157 bits (397),  Expect = 3e-43, Method: Composition-based stats.
 Identities = 81/202 (40%), Positives = 124/202 (61%), Gaps = 15/202 (7%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQ  56
             ++  EFS +PSYA +  A+  YE+ +A+    G ++  L   +K+ N+AKS FDRD A+Q
Sbjct  3465  SVTQEFSHIPSYAEYERAKSIYEKVLADSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQ  3524

Query  57    RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP  116
             +KL+ MA++AMT MYK+AR  D+RAK+ S++  +LF+ML+K+D++ LN + + A  G VP
Sbjct  3525  KKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQANSGVVP  3584

Query  117   LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSE-----  171
             L  +P+  + KL +VIPD  T+    +G   TY++ +W I  V DAD   +  +      
Sbjct  3585  LATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDCVTDADGTELHPTSTGSGL  3644

Query  172   ---ISMDNSPNLAWPLIVTALR  190
                IS D   N+AWPL V   R
Sbjct  3645  TYCISGD---NIAWPLKVNLTR  3663


>sp|B2A4X5|GLSA_NATTJ Glutaminase OS=Natranaerobius thermophilus 
(strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF) OX=457570 
GN=glsA PE=3 SV=1
Length=308

 Score = 32.7 bits (73),  Expect = 1.8, Method: Compositional matrix adjust.
 Identities = 26/93 (28%), Positives = 41/93 (44%), Gaps = 11/93 (12%)

Query  94   MLRKLDNDALNNIINN----ARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTY  149
            M+  ++ + L   + N    A DG +P  I  L  A K      D+  +    DG +  Y
Sbjct  1    MINNVNQEILRAFVENNRPLAHDGRLPTYIPALMNANK-----QDFGIHITELDGNSHYY  55

Query  150  ASALWEIQQVVDADSKIVQLSEISMDNSPNLAW  182
             S  ++I   V + SKI+ L+   MDN   L +
Sbjct  56   GS--FQIPFTVQSISKIITLAMAIMDNGEELVF  86


>sp|P31759|FRZF_MYXXA Protein methyltransferase FrzF OS=Myxococcus 
xanthus OX=34 GN=frzF PE=4 SV=1
Length=593

 Score = 31.6 bits (70),  Expect = 5.4, Method: Compositional matrix adjust.
 Identities = 20/67 (30%), Positives = 31/67 (46%), Gaps = 3/67 (4%)

Query  20   EAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDK  79
            E Y Q +     E  L+ L   + V  +EF RDA   R LEK     +  +  ++R E +
Sbjct  49   EHYIQRLTGAGGEEELRSLLPLVTVGHTEFFRDAKQFRALEK---SVLPDLVSRSRREMR  105

Query  80   RAKVTSA  86
            +  + SA
Sbjct  106  KVSIWSA  112


>sp|Q8D219|SYM_WIGBR Methionine--tRNA ligase OS=Wigglesworthia 
glossinidia brevipalpis OX=36870 GN=metG PE=3 SV=1
Length=550

 Score = 30.8 bits (68),  Expect = 8.2, Method: Compositional matrix adjust.
 Identities = 17/61 (28%), Positives = 27/61 (44%), Gaps = 4/61 (7%)

Query  137  TYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVK  196
            T+KN CD     + S  W+    V++ S+I Q     +    +L WP I+  +      K
Sbjct  263  TFKNLCDKKEKIFFSEFWD----VNSKSEIYQFIGKDVIYFHSLFWPAILHGINLKKPTK  318

Query  197  L  197
            L
Sbjct  319  L  319


>sp|Q8SSA8|CHK1_ENCCU Probable serine/threonine-protein kinase 
CHK1 homolog OS=Encephalitozoon cuniculi (strain GB-M1) OX=284813 
GN=CHK1 PE=3 SV=1
Length=414

 Score = 30.8 bits (68),  Expect = 9.0, Method: Compositional matrix adjust.
 Identities = 21/82 (26%), Positives = 33/82 (40%), Gaps = 7/82 (9%)

Query  53   AAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRK-LDNDALNNIINNAR  111
               Q  L  + DQAM  + +    ED+R  V++ M+        + LD   L       R
Sbjct  216  GGCQVPLSSIGDQAMGLVMRMTAKEDRRPSVSTVMKDPWVMQPNELLDESGL------CR  269

Query  112  DGCVPLNIIPLTTAAKLMVVIP  133
            D C   +++P  T + L    P
Sbjct  270  DSCRLFSLVPRQTGSALHFTQP  291



Lambda      K        H        a         alpha
   0.315    0.125    0.339    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 12295187284
Results from round 2


Query= YP_009725304.1 nsp8 [Severe acute respiratory syndrome coronavirus
2]

Length=198
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value
Sequences used in model and found again:

sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respi...  322     9e-101
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res...  322     9e-101
sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus 2...  321     2e-100
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus...  321     2e-100
sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute resp...  321     2e-100
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re...  321     2e-100
sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus H...  320     5e-100
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus...  320     5e-100
sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus R...  318     1e-99 
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus...  318     1e-99 
sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic ...  311     6e-97 
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi...  311     6e-97 
sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus 5...  309     2e-96 
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus...  309     2e-96 
sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus...  309     3e-96 
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir...  309     3e-96 
sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus...  308     5e-96 
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir...  308     5e-96 
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus...  306     3e-95 
sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus H...  305     5e-95 
sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus 1...  305     5e-95 
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus...  305     6e-95 
sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus H...  305     6e-95 
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus...  305     7e-95 
sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respi...  305     1e-94 
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res...  305     1e-94 
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir...  303     3e-94 
sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmiss...  300     3e-93 
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi...  300     3e-93 
sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus H...  296     7e-92 
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus...  296     7e-92 
sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus...  292     3e-90 
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir...  292     3e-90 
sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus...  291     3e-90 
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir...  291     3e-90 
sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus...  291     4e-90 
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir...  291     4e-90 
sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus...  291     8e-90 
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir...  291     8e-90 
sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronaviru...  290     1e-89 
sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronaviru...  290     1e-89 
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi...  290     1e-89 
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi...  290     1e-89 
sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus...  290     1e-89 
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir...  290     1e-89 
sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronaviru...  288     5e-89 
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi...  288     5e-89 
sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus...  288     6e-89 
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir...  288     6e-89 
sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus...  286     4e-88 
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir...  286     4e-88 
sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronaviru...  286     4e-88 
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi...  286     4e-88 
sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious b...  277     4e-85 
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious...  277     5e-85 
sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious ...  275     2e-84 
sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious b...  275     2e-84 
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou...  275     2e-84 
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious...  275     2e-84 

Sequences not found previously or not previously below threshold:

sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream vir...  37.0    0.10 
sp|Q008X5|R1A_WBV24 Replicase polyprotein 1a OS=White bream virus...  36.6    0.14 
sp|O14261|ATG11_SCHPO Taz1-interacting factor 1 OS=Schizosaccharo...  33.9    0.90 
sp|Q9V1E9|KTHY_PYRAB Probable thymidylate kinase OS=Pyrococcus ab...  33.1    1.2  
sp|A8G6V3|ATPF_PROM2 ATP synthase subunit b OS=Prochlorococcus ma...  31.6    2.7  
sp|A6NGH8|ANR61_HUMAN Ankyrin repeat domain-containing protein 61...  32.3    3.1  
sp|A3PEU1|ATPF_PROM0 ATP synthase subunit b OS=Prochlorococcus ma...  31.6    3.3  
sp|Q6NY52|THOC5_DANRE THO complex subunit 5 homolog OS=Danio reri...  31.6    4.7  
sp|Q4FRM3|RS20_PSYA2 Small ribosomal subunit protein bS20 OS=Psyc...  29.6    6.2  
sp|A2BT27|ATPF_PROMS ATP synthase subunit b OS=Prochlorococcus ma...  30.4    7.1  


>sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respiratory 
syndrome coronavirus OX=694009 GN=1a PE=1 SV=1
Length=4382

 Score = 322 bits (825),  Expect = 9e-101, Method: Composition-based stats.
 Identities = 193/198 (97%), Positives = 196/198 (99%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE
Sbjct  3920  AIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  3979

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3980  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4039

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNL
Sbjct  4040  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNL  4099

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4100  AWPLIVTALRANSAVKLQ  4117


>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute 
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073

 Score = 322 bits (825),  Expect = 9e-101, Method: Composition-based stats.
 Identities = 193/198 (97%), Positives = 196/198 (99%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE
Sbjct  3920  AIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  3979

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3980  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4039

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNL
Sbjct  4040  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNL  4099

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4100  AWPLIVTALRANSAVKLQ  4117


>sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus 
279/2005 OX=389167 GN=1a PE=3 SV=1
Length=4388

 Score = 321 bits (823),  Expect = 2e-100, Method: Composition-based stats.
 Identities = 192/198 (97%), Positives = 195/198 (98%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE
Sbjct  3926  AIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  3985

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3986  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4045

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNS NL
Sbjct  4046  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSQNL  4105

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4106  AWPLIVTALRANSAVKLQ  4123


>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus 
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079

 Score = 321 bits (823),  Expect = 2e-100, Method: Composition-based stats.
 Identities = 192/198 (97%), Positives = 195/198 (98%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE
Sbjct  3926  AIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  3985

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3986  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4045

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNS NL
Sbjct  4046  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSQNL  4105

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4106  AWPLIVTALRANSAVKLQ  4123


>sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute 
respiratory syndrome coronavirus 2 OX=2697049 PE=1 SV=1
Length=4405

 Score = 321 bits (822),  Expect = 2e-100, Method: Composition-based stats.
 Identities = 198/198 (100%), Positives = 198/198 (100%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE
Sbjct  3943  AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  4002

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  4003  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4062

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL
Sbjct  4063  PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  4122

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4123  AWPLIVTALRANSAVKLQ  4140


>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute 
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1 
SV=1
Length=7096

 Score = 321 bits (822),  Expect = 2e-100, Method: Composition-based stats.
 Identities = 198/198 (100%), Positives = 198/198 (100%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE
Sbjct  3943  AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  4002

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  4003  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4062

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL
Sbjct  4063  PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  4122

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4123  AWPLIVTALRANSAVKLQ  4140


>sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus 
HKU3 OX=442736 GN=1a PE=3 SV=1
Length=4376

 Score = 320 bits (819),  Expect = 5e-100, Method: Composition-based stats.
 Identities = 191/198 (96%), Positives = 195/198 (98%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAV+NGDSEVVLKKLKKSLNVAKSEFD DAAMQRKLE
Sbjct  3914  AIASEFSSLPSYAAYATAQEAYEQAVSNGDSEVVLKKLKKSLNVAKSEFDHDAAMQRKLE  3973

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3974  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4033

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNL
Sbjct  4034  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNL  4093

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4094  AWPLIVTALRANSAVKLQ  4111


>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus 
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067

 Score = 320 bits (819),  Expect = 5e-100, Method: Composition-based stats.
 Identities = 191/198 (96%), Positives = 195/198 (98%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAV+NGDSEVVLKKLKKSLNVAKSEFD DAAMQRKLE
Sbjct  3914  AIASEFSSLPSYAAYATAQEAYEQAVSNGDSEVVLKKLKKSLNVAKSEFDHDAAMQRKLE  3973

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3974  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4033

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNL
Sbjct  4034  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNL  4093

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4094  AWPLIVTALRANSAVKLQ  4111


>sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus 
Rp3/2004 OX=349344 GN=1a PE=3 SV=1
Length=4380

 Score = 318 bits (816),  Expect = 1e-99, Method: Composition-based stats.
 Identities = 190/198 (96%), Positives = 195/198 (98%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR+AAMQRKLE
Sbjct  3918  AIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRNAAMQRKLE  3977

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3978  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4037

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+M+NS NL
Sbjct  4038  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMENSSNL  4097

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4098  AWPLIVTALRANSAVKLQ  4115


>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus 
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071

 Score = 318 bits (816),  Expect = 1e-99, Method: Composition-based stats.
 Identities = 190/198 (96%), Positives = 195/198 (98%), Gaps = 0/198 (0%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             AIASEFSSLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR+AAMQRKLE
Sbjct  3918  AIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRNAAMQRKLE  3977

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII
Sbjct  3978  KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  4037

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             PLTTAAKLMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+M+NS NL
Sbjct  4038  PLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMENSSNL  4097

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPLIVTALRANSAVKLQ
Sbjct  4098  AWPLIVTALRANSAVKLQ  4115


>sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic 
diarrhea virus (strain CV777) OX=229032 GN=1a PE=1 SV=1
Length=4117

 Score = 311 bits (796),  Expect = 6e-97, Method: Composition-based stats.
 Identities = 86/198 (43%), Positives = 134/198 (68%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS +  LPSY  +  A++ YE AV NG    ++K+L+ ++NVAKSEFDR+A+ QRKL+
Sbjct  3663  SVASTYVGLPSYVIYENARQQYEDAVNNGSPPQLVKQLRHAMNVAKSEFDREASTQRKLD  3722

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA  QMYK+AR+ ++++KV SAM ++LF MLR+LD  +++ I+N A+DG VPL++I
Sbjct  3723  RMAEQAAAQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNLAKDGVVPLSVI  3782

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A KL +V  D ++Y          YA  +W I  + D D K+V + E++  N+ +L
Sbjct  3783  PAVSATKLNIVTSDIDSYNRIQREGCVHYAGTIWNIIDIKDNDGKVVHVKEVTAQNAESL  3842

Query  181   AWPLIVTALRANSAVKLQ  198
             +WPL++   R    VKLQ
Sbjct  3843  SWPLVLGCER---IVKLQ  3857


>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic 
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781

 Score = 311 bits (796),  Expect = 6e-97, Method: Composition-based stats.
 Identities = 86/198 (43%), Positives = 134/198 (68%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS +  LPSY  +  A++ YE AV NG    ++K+L+ ++NVAKSEFDR+A+ QRKL+
Sbjct  3663  SVASTYVGLPSYVIYENARQQYEDAVNNGSPPQLVKQLRHAMNVAKSEFDREASTQRKLD  3722

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA  QMYK+AR+ ++++KV SAM ++LF MLR+LD  +++ I+N A+DG VPL++I
Sbjct  3723  RMAEQAAAQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNLAKDGVVPLSVI  3782

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A KL +V  D ++Y          YA  +W I  + D D K+V + E++  N+ +L
Sbjct  3783  PAVSATKLNIVTSDIDSYNRIQREGCVHYAGTIWNIIDIKDNDGKVVHVKEVTAQNAESL  3842

Query  181   AWPLIVTALRANSAVKLQ  198
             +WPL++   R    VKLQ
Sbjct  3843  SWPLVLGCER---IVKLQ  3857


>sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus 
512/2005 OX=693999 GN=1a PE=3 SV=1
Length=4128

 Score = 309 bits (792),  Expect = 2e-96, Method: Composition-based stats.
 Identities = 86/198 (43%), Positives = 135/198 (68%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++A+ + +LPSY A+ TA+++YE A+ANG    ++K+L+ ++NVAKSEFDR+A+ QRKL+
Sbjct  3674  SVAATYVNLPSYLAYETARQSYEDALANGSPPQLVKQLRHAMNVAKSEFDREASTQRKLD  3733

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA +QMYK+AR+ ++++KV SAM ++LF MLR+LD  +++ I++ A+DG VPL+II
Sbjct  3734  RMAEQAASQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLAKDGVVPLSII  3793

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A KL +V+ D  +Y          YA  +W +  + D D K V   E+   N  +L
Sbjct  3794  PAVSATKLNIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAKEVVTSNVESL  3853

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPL +   R    +KLQ
Sbjct  3854  AWPLFLNCER---IIKLQ  3868


>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus 
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793

 Score = 309 bits (792),  Expect = 2e-96, Method: Composition-based stats.
 Identities = 86/198 (43%), Positives = 135/198 (68%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++A+ + +LPSY A+ TA+++YE A+ANG    ++K+L+ ++NVAKSEFDR+A+ QRKL+
Sbjct  3674  SVAATYVNLPSYLAYETARQSYEDALANGSPPQLVKQLRHAMNVAKSEFDREASTQRKLD  3733

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA +QMYK+AR+ ++++KV SAM ++LF MLR+LD  +++ I++ A+DG VPL+II
Sbjct  3734  RMAEQAASQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLAKDGVVPLSII  3793

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A KL +V+ D  +Y          YA  +W +  + D D K V   E+   N  +L
Sbjct  3794  PAVSATKLNIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAKEVVTSNVESL  3853

Query  181   AWPLIVTALRANSAVKLQ  198
             AWPL +   R    +KLQ
Sbjct  3854  AWPLFLNCER---IIKLQ  3868


>sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus 
NL63 OX=277944 GN=1a PE=1 SV=1
Length=4060

 Score = 309 bits (791),  Expect = 3e-96, Method: Composition-based stats.
 Identities = 91/198 (46%), Positives = 138/198 (70%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS F S+PSY A+  A++AYE A+ANG S  ++K+LK+++N+AKSEFD + ++Q+K+ 
Sbjct  3605  SVASSFVSMPSYIAYENARQAYEDAIANGSSSQLIKQLKRAMNIAKSEFDHEISVQKKIN  3664

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA TQMYK+ARS ++++KV SAM ++LF MLR+LD  ++  ++N ARDG VPL++I
Sbjct  3665  RMAEQAATQMYKEARSVNRKSKVISAMHSLLFGMLRRLDMSSVETVLNLARDGVVPLSVI  3724

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P T+A+KL +V PD  +Y       +  YA  +W +  V D D + V + EI+ +N   L
Sbjct  3725  PATSASKLTIVSPDLESYSKIVCDGSVHYAGVVWTLNDVKDNDGRPVHVKEITKENVETL  3784

Query  181   AWPLIVTALRANSAVKLQ  198
              WPLI+   R    VKLQ
Sbjct  3785  TWPLILNCER---VVKLQ  3799


>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus 
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729

 Score = 309 bits (791),  Expect = 3e-96, Method: Composition-based stats.
 Identities = 91/198 (46%), Positives = 138/198 (70%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS F S+PSY A+  A++AYE A+ANG S  ++K+LK+++N+AKSEFD + ++Q+K+ 
Sbjct  3605  SVASSFVSMPSYIAYENARQAYEDAIANGSSSQLIKQLKRAMNIAKSEFDHEISVQKKIN  3664

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA TQMYK+ARS ++++KV SAM ++LF MLR+LD  ++  ++N ARDG VPL++I
Sbjct  3665  RMAEQAATQMYKEARSVNRKSKVISAMHSLLFGMLRRLDMSSVETVLNLARDGVVPLSVI  3724

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P T+A+KL +V PD  +Y       +  YA  +W +  V D D + V + EI+ +N   L
Sbjct  3725  PATSASKLTIVSPDLESYSKIVCDGSVHYAGVVWTLNDVKDNDGRPVHVKEITKENVETL  3784

Query  181   AWPLIVTALRANSAVKLQ  198
              WPLI+   R    VKLQ
Sbjct  3785  TWPLILNCER---VVKLQ  3799


>sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus 
229E OX=11137 GN=1a PE=1 SV=1
Length=4085

 Score = 308 bits (790),  Expect = 5e-96, Method: Composition-based stats.
 Identities = 91/198 (46%), Positives = 144/198 (73%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS F  +PS+ A+ TA++ YE AVANG S  ++K+LKK++NVAK+EFDR++++Q+K+ 
Sbjct  3630  SVASSFVGMPSFVAYETARQEYENAVANGSSPQIIKQLKKAMNVAKAEFDRESSVQKKIN  3689

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA   MYK+AR+ ++++KV SAM ++LF MLR+LD  +++ I+N AR+G VPL++I
Sbjct  3690  RMAEQAAAAMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNMARNGVVPLSVI  3749

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P T+AA+L+VV+PD++++          YA  +W +Q+V D D K V L +++ +N   L
Sbjct  3750  PATSAARLVVVVPDHDSFVKMMVDGFVHYAGVVWTLQEVKDNDGKNVHLKDVTKENQEIL  3809

Query  181   AWPLIVTALRANSAVKLQ  198
              WPLI+T  R    VKLQ
Sbjct  3810  VWPLILTCER---VVKLQ  3824


>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus 
229E OX=11137 GN=rep PE=1 SV=1
Length=6758

 Score = 308 bits (790),  Expect = 5e-96, Method: Composition-based stats.
 Identities = 91/198 (46%), Positives = 144/198 (73%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS F  +PS+ A+ TA++ YE AVANG S  ++K+LKK++NVAK+EFDR++++Q+K+ 
Sbjct  3630  SVASSFVGMPSFVAYETARQEYENAVANGSSPQIIKQLKKAMNVAKAEFDRESSVQKKIN  3689

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +MA+QA   MYK+AR+ ++++KV SAM ++LF MLR+LD  +++ I+N AR+G VPL++I
Sbjct  3690  RMAEQAAAAMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNMARNGVVPLSVI  3749

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P T+AA+L+VV+PD++++          YA  +W +Q+V D D K V L +++ +N   L
Sbjct  3750  PATSAARLVVVVPDHDSFVKMMVDGFVHYAGVVWTLQEVKDNDGKNVHLKDVTKENQEIL  3809

Query  181   AWPLIVTALRANSAVKLQ  198
              WPLI+T  R    VKLQ
Sbjct  3810  VWPLILTCER---VVKLQ  3824


>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus 
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182

 Score = 306 bits (783),  Expect = 3e-95, Method: Composition-based stats.
 Identities = 101/200 (51%), Positives = 147/200 (74%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  SEFS L SYA    AQ +Y++A+ +GD S  VLK L+K++N+AK+ +++D A+ RKL
Sbjct  4020  ATLSEFSHLASYAELEAAQSSYQKALNSGDASPQVLKALQKAVNIAKNAYEKDKAVARKL  4079

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I+NAR+GCVPL++
Sbjct  4080  ERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVISNARNGCVPLSV  4139

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             +PL  + KL VVIPD   +       + +YA ALW+I  + + D ++V+ S+++ + + +
Sbjct  4140  VPLCASNKLRVVIPDITIWNKVVTWPSLSYAGALWDISLINNVDGEVVKSSDVT-ETNES  4198

Query  180   LAWPLIVTALR-ANSAVKLQ  198
             L WPL++   R A+SAV LQ
Sbjct  4199  LTWPLVLECTRAASSAVTLQ  4218


>sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus 
HKU5 OX=694008 GN=1a PE=3 SV=1
Length=4481

 Score = 305 bits (782),  Expect = 5e-95, Method: Composition-based stats.
 Identities = 101/200 (51%), Positives = 147/200 (74%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  SEFS L SYA    AQ +Y++A+ +GD S  VLK L+K++N+AK+ +++D A+ RKL
Sbjct  4020  ATLSEFSHLASYAELEAAQSSYQKALNSGDASPQVLKALQKAVNIAKNAYEKDKAVARKL  4079

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I+NAR+GCVPL++
Sbjct  4080  ERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVISNARNGCVPLSV  4139

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             +PL  + KL VVIPD   +       + +YA ALW+I  + + D ++V+ S+++ + + +
Sbjct  4140  VPLCASNKLRVVIPDITIWNKVVTWPSLSYAGALWDISLINNVDGEVVKSSDVT-ETNES  4198

Query  180   LAWPLIVTALR-ANSAVKLQ  198
             L WPL++   R A+SAV LQ
Sbjct  4199  LTWPLVLECTRAASSAVTLQ  4218


>sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus 
133/2005 OX=389230 GN=1a PE=3 SV=1
Length=4441

 Score = 305 bits (782),  Expect = 5e-95, Method: Composition-based stats.
 Identities = 100/200 (50%), Positives = 151/200 (76%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  +EFS L +YA   TAQ +Y++A+ +GD S  VLK L+K++NVAK+ +++D A+ RKL
Sbjct  3980  ATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKL  4039

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GCVPL+I
Sbjct  4040  ERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSI  4099

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             +PL  + KL VVIPD + +    +  + +YA +LW++  + + D+++V+ +++ ++ + +
Sbjct  4100  VPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDVTVINNVDNEVVKPTDV-VETNES  4158

Query  180   LAWPLIVTALRA-NSAVKLQ  198
             L WPL++   RA +SAVKLQ
Sbjct  4159  LTWPLVIECSRASSSAVKLQ  4178


>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus 
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126

 Score = 305 bits (782),  Expect = 6e-95, Method: Composition-based stats.
 Identities = 100/200 (50%), Positives = 151/200 (76%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  +EFS L +YA   TAQ +Y++A+ +GD S  VLK L+K++NVAK+ +++D A+ RKL
Sbjct  3980  ATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKL  4039

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GCVPL+I
Sbjct  4040  ERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSI  4099

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             +PL  + KL VVIPD + +    +  + +YA +LW++  + + D+++V+ +++ ++ + +
Sbjct  4100  VPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDVTVINNVDNEVVKPTDV-VETNES  4158

Query  180   LAWPLIVTALRA-NSAVKLQ  198
             L WPL++   RA +SAVKLQ
Sbjct  4159  LTWPLVIECSRASSSAVKLQ  4178


>sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus 
HKU4 OX=694007 GN=1a PE=1 SV=1
Length=4434

 Score = 305 bits (781),  Expect = 6e-95, Method: Composition-based stats.
 Identities = 100/200 (50%), Positives = 151/200 (76%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  +EFS L +YA   TAQ +Y++A+ +GD S  VLK L+K++NVAK+ +++D A+ RKL
Sbjct  3973  ATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKL  4032

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GCVPL+I
Sbjct  4033  ERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSI  4092

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             +PL  + KL VVIPD + +    +  + +YA +LW+I  + + D+++V+ +++ ++ + +
Sbjct  4093  VPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVVKPTDV-VETNES  4151

Query  180   LAWPLIVTALR-ANSAVKLQ  198
             L WPL++   R ++SAVKLQ
Sbjct  4152  LTWPLVIECSRSSSSAVKLQ  4171


>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus 
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119

 Score = 305 bits (781),  Expect = 7e-95, Method: Composition-based stats.
 Identities = 100/200 (50%), Positives = 151/200 (76%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  +EFS L +YA   TAQ +Y++A+ +GD S  VLK L+K++NVAK+ +++D A+ RKL
Sbjct  3973  ATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKL  4032

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GCVPL+I
Sbjct  4033  ERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSI  4092

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             +PL  + KL VVIPD + +    +  + +YA +LW+I  + + D+++V+ +++ ++ + +
Sbjct  4093  VPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVVKPTDV-VETNES  4151

Query  180   LAWPLIVTALR-ANSAVKLQ  198
             L WPL++   R ++SAVKLQ
Sbjct  4152  LTWPLVIECSRSSSSAVKLQ  4171


>sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respiratory 
syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) 
OX=1263720 GN=1a PE=1 SV=1
Length=4391

 Score = 305 bits (780),  Expect = 1e-94, Method: Composition-based stats.
 Identities = 106/200 (53%), Positives = 151/200 (76%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  SEFS L ++A    AQ+AY++A+ +GD S  VLK L+K++N+AK+ +++D A+ RKL
Sbjct  3929  ATLSEFSHLATFAELEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKNAYEKDKAVARKL  3988

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MADQAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN II+NAR+GC+PL++
Sbjct  3989  ERMADQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIPLSV  4048

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IPL  + KL VVIPD+  +       +  YA ALW+I  + + D++IV+ S++ +D++ N
Sbjct  4049  IPLCASNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDV-VDSNEN  4107

Query  180   LAWPLIVTALRAN-SAVKLQ  198
             L WPL++   RA+ SAVKLQ
Sbjct  4108  LTWPLVLECTRASTSAVKLQ  4127


>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East 
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) 
OX=1263720 GN=rep PE=1 SV=1
Length=7078

 Score = 305 bits (780),  Expect = 1e-94, Method: Composition-based stats.
 Identities = 106/200 (53%), Positives = 151/200 (76%), Gaps = 3/200 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A  SEFS L ++A    AQ+AY++A+ +GD S  VLK L+K++N+AK+ +++D A+ RKL
Sbjct  3929  ATLSEFSHLATFAELEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKNAYEKDKAVARKL  3988

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MADQAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN II+NAR+GC+PL++
Sbjct  3989  ERMADQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIPLSV  4048

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IPL  + KL VVIPD+  +       +  YA ALW+I  + + D++IV+ S++ +D++ N
Sbjct  4049  IPLCASNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDV-VDSNEN  4107

Query  180   LAWPLIVTALRAN-SAVKLQ  198
             L WPL++   RA+ SAVKLQ
Sbjct  4108  LTWPLVLECTRASTSAVKLQ  4127


>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus 
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709

 Score = 303 bits (776),  Expect = 3e-94, Method: Composition-based stats.
 Identities = 85/198 (43%), Positives = 130/198 (66%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS +++LPS+ A+  A+   E+A  N  S  +LK+L K+ N+AKSEF+R+A++Q+KL+
Sbjct  3583  SVASAYAALPSWIAYEKARADLEEAKKNDVSPQLLKQLTKACNIAKSEFEREASVQKKLD  3642

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMA+QA   MYK+AR+ D+++K+ SAM ++LF ML+KLD  ++N II  AR+G +PL+II
Sbjct  3643  KMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIEQARNGVLPLSII  3702

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A +L+VV P+              YA A+W I +V DA+   V L E++  N  N+
Sbjct  3703  PAASATRLIVVTPNLEVLSKVRQENNVHYAGAIWSIVEVKDANGAQVHLKEVTAANELNI  3762

Query  181   AWPLIVTALRANSAVKLQ  198
              WPL +T  R     KLQ
Sbjct  3763  TWPLSITCER---TTKLQ  3777


>sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmissible 
gastroenteritis coronavirus (strain Purdue) OX=11151 
GN=1a PE=1 SV=1
Length=4017

 Score = 300 bits (769),  Expect = 3e-93, Method: Composition-based stats.
 Identities = 84/198 (42%), Positives = 130/198 (66%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS +++LPS+ A   A+   E+A  N  S  +LK+L K+ N+AKS+F+R+A++Q+KL+
Sbjct  3558  SVASAYAALPSWIALEKARADLEEAKKNDVSPQILKQLTKAFNIAKSDFEREASVQKKLD  3617

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMA+QA   MYK+AR+ D+++K+ SAM ++LF ML+KLD  ++N II+ AR+G +PL+II
Sbjct  3618  KMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSII  3677

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A +L+V+ P    +          YA A+W I +V DA+   V L E++  N  NL
Sbjct  3678  PAASATRLVVITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAANELNL  3737

Query  181   AWPLIVTALRANSAVKLQ  198
              WPL +T  R     KLQ
Sbjct  3738  TWPLSITCER---TTKLQ  3752


>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible 
gastroenteritis coronavirus (strain Purdue) OX=11151 
GN=rep PE=1 SV=1
Length=6684

 Score = 300 bits (769),  Expect = 3e-93, Method: Composition-based stats.
 Identities = 84/198 (42%), Positives = 130/198 (66%), Gaps = 3/198 (2%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             ++AS +++LPS+ A   A+   E+A  N  S  +LK+L K+ N+AKS+F+R+A++Q+KL+
Sbjct  3558  SVASAYAALPSWIALEKARADLEEAKKNDVSPQILKQLTKAFNIAKSDFEREASVQKKLD  3617

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             KMA+QA   MYK+AR+ D+++K+ SAM ++LF ML+KLD  ++N II+ AR+G +PL+II
Sbjct  3618  KMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSII  3677

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P  +A +L+V+ P    +          YA A+W I +V DA+   V L E++  N  NL
Sbjct  3678  PAASATRLVVITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAANELNL  3737

Query  181   AWPLIVTALRANSAVKLQ  198
              WPL +T  R     KLQ
Sbjct  3738  TWPLSITCER---TTKLQ  3752


>sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus 
HKU9 OX=694006 GN=1a PE=3 SV=1
Length=4248

 Score = 296 bits (759),  Expect = 7e-92, Method: Composition-based stats.
 Identities = 114/200 (57%), Positives = 150/200 (75%), Gaps = 2/200 (1%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             A+ASEFS+L SY  +  AQ+AY+ AVA G     +  LKK++NVAKS  D+D A  RKLE
Sbjct  3783  AVASEFSNLSSYVDYENAQKAYDTAVATGAPASTVNALKKAMNVAKSVLDKDVATTRKLE  3842

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +M++ AMT MYKQAR+ED+R+KVT+AMQTMLF M+R+LD+DAL+NI+NNAR+G VPL +I
Sbjct  3843  RMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILNNARNGVVPLGVI  3902

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P T A KL++V+PD++ Y  T    T TYA + W++ QV DAD K V  ++I+ +NS NL
Sbjct  3903  PRTAANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGKTVNATDITRENSVNL  3962

Query  181   AWPLIVTALR--ANSAVKLQ  198
             AWPL+VTA R  A S VKLQ
Sbjct  3963  AWPLVVTAQRQQATSPVKLQ  3982


>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus 
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930

 Score = 296 bits (759),  Expect = 7e-92, Method: Composition-based stats.
 Identities = 114/200 (57%), Positives = 150/200 (75%), Gaps = 2/200 (1%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE  60
             A+ASEFS+L SY  +  AQ+AY+ AVA G     +  LKK++NVAKS  D+D A  RKLE
Sbjct  3783  AVASEFSNLSSYVDYENAQKAYDTAVATGAPASTVNALKKAMNVAKSVLDKDVATTRKLE  3842

Query  61    KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII  120
             +M++ AMT MYKQAR+ED+R+KVT+AMQTMLF M+R+LD+DAL+NI+NNAR+G VPL +I
Sbjct  3843  RMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILNNARNGVVPLGVI  3902

Query  121   PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL  180
             P T A KL++V+PD++ Y  T    T TYA + W++ QV DAD K V  ++I+ +NS NL
Sbjct  3903  PRTAANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGKTVNATDITRENSVNL  3962

Query  181   AWPLIVTALR--ANSAVKLQ  198
             AWPL+VTA R  A S VKLQ
Sbjct  3963  AWPLVVTAQRQQATSPVKLQ  3982


>sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus 
(strain 2) OX=76344 GN=1a PE=3 SV=1
Length=4416

 Score = 292 bits (747),  Expect = 3e-90, Method: Composition-based stats.
 Identities = 93/201 (46%), Positives = 138/201 (69%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A A+G + +  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  3959  ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL  4018

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4019  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKLDNQALNSILDNAVKGCVPLNA  4078

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP  T+  L +++PD   +    D    TYA  +W IQ + DAD  + QL+EI +    N
Sbjct  4079  IPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQLNEIDV----N  4134

Query  180   LAWPLIVTALRAN--SAVKLQ  198
             + WPL++ A R N  S+V LQ
Sbjct  4135  ITWPLVIAANRHNEVSSVVLQ  4155


>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus 
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124

 Score = 292 bits (747),  Expect = 3e-90, Method: Composition-based stats.
 Identities = 93/201 (46%), Positives = 138/201 (69%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A A+G + +  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  3959  ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL  4018

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4019  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKLDNQALNSILDNAVKGCVPLNA  4078

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP  T+  L +++PD   +    D    TYA  +W IQ + DAD  + QL+EI +    N
Sbjct  4079  IPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQLNEIDV----N  4134

Query  180   LAWPLIVTALRAN--SAVKLQ  198
             + WPL++ A R N  S+V LQ
Sbjct  4135  ITWPLVIAANRHNEVSSVVLQ  4155


>sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus 
(strain Mebus) OX=11132 GN=1a PE=3 SV=1
Length=4383

 Score = 291 bits (746),  Expect = 3e-90, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLHEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATALQ  4122


>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus 
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094

 Score = 291 bits (746),  Expect = 3e-90, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLHEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATALQ  4122


>sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus 
(strain Quebec) OX=11133 GN=1a PE=3 SV=1
Length=4383

 Score = 291 bits (745),  Expect = 4e-90, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLHEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATVLQ  4122


>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus 
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059

 Score = 291 bits (745),  Expect = 4e-90, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLHEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATVLQ  4122


>sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus 
HKU1 (isolate N1) OX=443239 GN=1a PE=1 SV=1
Length=4471

 Score = 291 bits (744),  Expect = 8e-90, Method: Composition-based stats.
 Identities = 90/195 (46%), Positives = 131/195 (67%), Gaps = 5/195 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++    A  +G  ++  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  4014  ALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNIAKSVYERDKAVARKL  4073

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPL+ 
Sbjct  4074  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLSA  4133

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +VIPD   +    D    TYA ++W IQ V DAD    QL++IS+D++  
Sbjct  4134  IPALAANTLTIVIPDKQVFDKVVDNVYVTYAGSVWHIQTVQDADGINKQLTDISVDSN--  4191

Query  180   LAWPLIVTALRANSA  194
               WPL++ A R N  
Sbjct  4192  --WPLVIIANRYNEV  4204


>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus 
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182

 Score = 291 bits (744),  Expect = 8e-90, Method: Composition-based stats.
 Identities = 90/195 (46%), Positives = 131/195 (67%), Gaps = 5/195 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++    A  +G  ++  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  4014  ALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNIAKSVYERDKAVARKL  4073

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPL+ 
Sbjct  4074  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLSA  4133

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +VIPD   +    D    TYA ++W IQ V DAD    QL++IS+D++  
Sbjct  4134  IPALAANTLTIVIPDKQVFDKVVDNVYVTYAGSVWHIQTVQDADGINKQLTDISVDSN--  4191

Query  180   LAWPLIVTALRANSA  194
               WPL++ A R N  
Sbjct  4192  --WPLVIIANRYNEV  4204


>sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronavirus 
(strain 98TXSF-110-LUN) OX=233264 GN=1a PE=3 SV=1
Length=4383

 Score = 290 bits (742),  Expect = 1e-89, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 137/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL+EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATVLQ  4122


>sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronavirus 
(strain 98TXSF-110-ENT) OX=233262 GN=1a PE=3 SV=1
Length=4383

 Score = 290 bits (742),  Expect = 1e-89, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 137/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL+EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATVLQ  4122


>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus 
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094

 Score = 290 bits (742),  Expect = 1e-89, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 137/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL+EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATVLQ  4122


>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus 
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094

 Score = 290 bits (742),  Expect = 1e-89, Method: Composition-based stats.
 Identities = 94/201 (47%), Positives = 137/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A ++G + +  LK+L+K+ N+AKS ++RD A+ RKL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAYERDRAVARKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL+EIS D +  
Sbjct  4046  IPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRHNEVSATVLQ  4122


>sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus 
HKU1 (isolate N5) OX=443241 GN=1a PE=3 SV=1
Length=4421

 Score = 290 bits (742),  Expect = 1e-89, Method: Composition-based stats.
 Identities = 89/195 (46%), Positives = 131/195 (67%), Gaps = 5/195 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++    A  +G  ++  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  3964  ALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNIAKSVYERDKAVARKL  4023

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPL+ 
Sbjct  4024  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLSA  4083

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L ++IPD   +    D    TYA ++W IQ V DAD    QL++IS+D++  
Sbjct  4084  IPALAANTLTIIIPDKQVFDKVVDNVYVTYAGSVWHIQTVQDADGINKQLTDISVDSN--  4141

Query  180   LAWPLIVTALRANSA  194
               WPL++ A R N  
Sbjct  4142  --WPLVIIANRYNEV  4154


>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus 
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132

 Score = 290 bits (742),  Expect = 1e-89, Method: Composition-based stats.
 Identities = 89/195 (46%), Positives = 131/195 (67%), Gaps = 5/195 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++    A  +G  ++  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  3964  ALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNIAKSVYERDKAVARKL  4023

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPL+ 
Sbjct  4024  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLSA  4083

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L ++IPD   +    D    TYA ++W IQ V DAD    QL++IS+D++  
Sbjct  4084  IPALAANTLTIIIPDKQVFDKVVDNVYVTYAGSVWHIQTVQDADGINKQLTDISVDSN--  4141

Query  180   LAWPLIVTALRANSA  194
               WPL++ A R N  
Sbjct  4142  --WPLVIIANRYNEV  4154


>sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronavirus 
(strain A59) OX=11142 GN=1a PE=1 SV=1
Length=4468

 Score = 288 bits (738),  Expect = 5e-89, Method: Composition-based stats.
 Identities = 93/201 (46%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A A+G + +  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  4011  ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL  4070

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4071  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4130

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP  T+  L +++PD   +    D    TYA  +W IQ + DAD  + QL+EI +    N
Sbjct  4131  IPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDV----N  4186

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  S V LQ
Sbjct  4187  STWPLVIAANRHNEVSTVVLQ  4207


>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus 
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176

 Score = 288 bits (738),  Expect = 5e-89, Method: Composition-based stats.
 Identities = 93/201 (46%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A A+G + +  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  4011  ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL  4070

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4071  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4130

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP  T+  L +++PD   +    D    TYA  +W IQ + DAD  + QL+EI +    N
Sbjct  4131  IPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDV----N  4186

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  S V LQ
Sbjct  4187  STWPLVIAANRHNEVSTVVLQ  4207


>sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus 
HKU1 (isolate N2) OX=443240 GN=1a PE=3 SV=1
Length=4441

 Score = 288 bits (737),  Expect = 6e-89, Method: Composition-based stats.
 Identities = 89/195 (46%), Positives = 130/195 (67%), Gaps = 5/195 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++    A  +G  ++  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  3984  ALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNIAKSVYERDKAVARKL  4043

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4044  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4103

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L ++IPD   +    D     YA ++W IQ V DAD    QL++IS+D++  
Sbjct  4104  IPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQTVQDADGINKQLTDISVDSN--  4161

Query  180   LAWPLIVTALRANSA  194
               WPL++ A R N  
Sbjct  4162  --WPLVIIANRYNEV  4174


>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus 
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152

 Score = 288 bits (737),  Expect = 6e-89, Method: Composition-based stats.
 Identities = 89/195 (46%), Positives = 130/195 (67%), Gaps = 5/195 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++    A  +G  ++  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  3984  ALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNIAKSVYERDKAVARKL  4043

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4044  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4103

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L ++IPD   +    D     YA ++W IQ V DAD    QL++IS+D++  
Sbjct  4104  IPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQTVQDADGINKQLTDISVDSN--  4161

Query  180   LAWPLIVTALRANSA  194
               WPL++ A R N  
Sbjct  4162  --WPLVIIANRYNEV  4174


>sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus 
OC43 OX=31631 GN=1a PE=1 SV=1
Length=4383

 Score = 286 bits (731),  Expect = 4e-88, Method: Composition-based stats.
 Identities = 93/201 (46%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A  +G + +  LK+L+K+ N+AKS ++RD A+ +KL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAYERDRAVAKKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL+EIS D +  
Sbjct  4046  IPSLAANTLNIIVPDKSVYDQIVDNIYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRYNEVSATVLQ  4122


>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus 
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095

 Score = 286 bits (731),  Expect = 4e-88, Method: Composition-based stats.
 Identities = 93/201 (46%), Positives = 136/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A  +G + +  LK+L+K+ N+AKS ++RD A+ +KL
Sbjct  3926  ALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAYERDRAVAKKL  3985

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  3986  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4045

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP   A  L +++PD + Y    D    TYA  +W+IQ + D+D    QL+EIS D +  
Sbjct  4046  IPSLAANTLNIIVPDKSVYDQIVDNIYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN--  4103

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL++ A R N  SA  LQ
Sbjct  4104  --WPLVIIANRYNEVSATVLQ  4122


>sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronavirus 
(strain JHM) OX=11144 GN=1a PE=1 SV=1
Length=4474

 Score = 286 bits (731),  Expect = 4e-88, Method: Composition-based stats.
 Identities = 93/201 (46%), Positives = 137/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A A+G + +  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  4017  ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL  4076

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4077  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4136

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP  T+  L +++PD   +    D    TYA  +W IQ + DAD  + QL+EI +    N
Sbjct  4137  IPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDV----N  4192

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL+++A R N  S V LQ
Sbjct  4193  STWPLVISANRHNEVSTVVLQ  4213


>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus 
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180

 Score = 286 bits (731),  Expect = 4e-88, Method: Composition-based stats.
 Identities = 93/201 (46%), Positives = 137/201 (68%), Gaps = 7/201 (3%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL  59
             A+ SEF ++ S+  +  A++  ++A A+G + +  +K+L+K+ N+AKS ++RD A+ RKL
Sbjct  4017  ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL  4076

Query  60    EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI  119
             E+MAD A+T MYK+AR  DK++KV SA+QTMLF+M+RKLDN ALN+I++NA  GCVPLN 
Sbjct  4077  ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA  4136

Query  120   IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN  179
             IP  T+  L +++PD   +    D    TYA  +W IQ + DAD  + QL+EI +    N
Sbjct  4137  IPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDV----N  4192

Query  180   LAWPLIVTALRAN--SAVKLQ  198
               WPL+++A R N  S V LQ
Sbjct  4193  STWPLVISANRHNEVSTVVLQ  4213


>sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious 
bronchitis virus (strain M41) OX=11127 GN=1a PE=1 SV=1
Length=3953

 Score = 277 bits (708),  Expect = 4e-85, Method: Composition-based stats.
 Identities = 78/199 (39%), Positives = 122/199 (61%), Gaps = 9/199 (5%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQ  56
             ++  EFS +PSYA +  A+  YE+ +A+    G ++  L   +K+ N+AKS FDRD A+Q
Sbjct  3465  SVTQEFSHIPSYAEYERAKSIYEKVLADSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQ  3524

Query  57    RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP  116
             +KL+ MA++AMT MYK+AR  D+RAK+ S++  +LF+ML+K+D++ LN + + A  G VP
Sbjct  3525  KKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQANSGVVP  3584

Query  117   LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-  175
             L  +P+  + KL +VIPD  T+    +G   TY++ +W I  V DAD   +  +      
Sbjct  3585  LATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDCVTDADGTELHPTSTGSGL  3644

Query  176   ----NSPNLAWPLIVTALR  190
                 +  N+AWPL V   R
Sbjct  3645  TYCISGDNIAWPLKVNLTR  3663


>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious 
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631

 Score = 277 bits (708),  Expect = 5e-85, Method: Composition-based stats.
 Identities = 78/199 (39%), Positives = 122/199 (61%), Gaps = 9/199 (5%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQ  56
             ++  EFS +PSYA +  A+  YE+ +A+    G ++  L   +K+ N+AKS FDRD A+Q
Sbjct  3465  SVTQEFSHIPSYAEYERAKSIYEKVLADSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQ  3524

Query  57    RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP  116
             +KL+ MA++AMT MYK+AR  D+RAK+ S++  +LF+ML+K+D++ LN + + A  G VP
Sbjct  3525  KKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQANSGVVP  3584

Query  117   LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-  175
             L  +P+  + KL +VIPD  T+    +G   TY++ +W I  V DAD   +  +      
Sbjct  3585  LATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDCVTDADGTELHPTSTGSGL  3644

Query  176   ----NSPNLAWPLIVTALR  190
                 +  N+AWPL V   R
Sbjct  3645  TYCISGDNIAWPLKVNLTR  3663


>sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious 
bronchitis virus (strain Beaudette CK) OX=160235 GN=1a PE=3 
SV=1
Length=3951

 Score = 275 bits (703),  Expect = 2e-84, Method: Composition-based stats.
 Identities = 77/199 (39%), Positives = 122/199 (61%), Gaps = 9/199 (5%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQ  56
             ++  EFS +PSYA +  A+  YE+ + +    G ++  L   +K+ N+AKS FDRD A+Q
Sbjct  3463  SVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQ  3522

Query  57    RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP  116
             +KL+ MA++AMT MYK+AR  D+RAK+ S++  +LF+ML+K+D++ LN + + A  G VP
Sbjct  3523  KKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVP  3582

Query  117   LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-  175
             L  +P+  + KL +VIPD  T+    +G   TY++ +W I  V+DAD   +  +      
Sbjct  3583  LATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGL  3642

Query  176   ----NSPNLAWPLIVTALR  190
                 +  N+AWPL V   R
Sbjct  3643  TYCISGANIAWPLKVNLTR  3661


>sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious 
bronchitis virus (strain Beaudette) OX=11122 GN=1a PE=1 SV=1
Length=3951

 Score = 275 bits (703),  Expect = 2e-84, Method: Composition-based stats.
 Identities = 77/199 (39%), Positives = 122/199 (61%), Gaps = 9/199 (5%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQ  56
             ++  EFS +PSYA +  A+  YE+ + +    G ++  L   +K+ N+AKS FDRD A+Q
Sbjct  3463  SVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQ  3522

Query  57    RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP  116
             +KL+ MA++AMT MYK+AR  D+RAK+ S++  +LF+ML+K+D++ LN + + A  G VP
Sbjct  3523  KKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVP  3582

Query  117   LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-  175
             L  +P+  + KL +VIPD  T+    +G   TY++ +W I  V+DAD   +  +      
Sbjct  3583  LATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGL  3642

Query  176   ----NSPNLAWPLIVTALR  190
                 +  N+AWPL V   R
Sbjct  3643  TYCISGANIAWPLKVNLTR  3661


>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious 
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep 
PE=3 SV=1
Length=6629

 Score = 275 bits (703),  Expect = 2e-84, Method: Composition-based stats.
 Identities = 77/199 (39%), Positives = 122/199 (61%), Gaps = 9/199 (5%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQ  56
             ++  EFS +PSYA +  A+  YE+ + +    G ++  L   +K+ N+AKS FDRD A+Q
Sbjct  3463  SVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQ  3522

Query  57    RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP  116
             +KL+ MA++AMT MYK+AR  D+RAK+ S++  +LF+ML+K+D++ LN + + A  G VP
Sbjct  3523  KKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVP  3582

Query  117   LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-  175
             L  +P+  + KL +VIPD  T+    +G   TY++ +W I  V+DAD   +  +      
Sbjct  3583  LATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGL  3642

Query  176   ----NSPNLAWPLIVTALR  190
                 +  N+AWPL V   R
Sbjct  3643  TYCISGANIAWPLKVNLTR  3661


>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious 
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1 
SV=1
Length=6629

 Score = 275 bits (703),  Expect = 2e-84, Method: Composition-based stats.
 Identities = 77/199 (39%), Positives = 122/199 (61%), Gaps = 9/199 (5%)

Query  1     AIASEFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQ  56
             ++  EFS +PSYA +  A+  YE+ + +    G ++  L   +K+ N+AKS FDRD A+Q
Sbjct  3463  SVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQ  3522

Query  57    RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP  116
             +KL+ MA++AMT MYK+AR  D+RAK+ S++  +LF+ML+K+D++ LN + + A  G VP
Sbjct  3523  KKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVP  3582

Query  117   LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-  175
             L  +P+  + KL +VIPD  T+    +G   TY++ +W I  V+DAD   +  +      
Sbjct  3583  LATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGL  3642

Query  176   ----NSPNLAWPLIVTALR  190
                 +  N+AWPL V   R
Sbjct  3643  TYCISGANIAWPLKVNLTR  3661


>sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream 
virus (isolate Blicca bjoerkna L./Germany/DF24/00) OX=766180 
GN=rep PE=1 SV=1
Length=6872

 Score = 37.0 bits (84),  Expect = 0.10, Method: Composition-based stats.
 Identities = 35/187 (19%), Positives = 66/187 (35%), Gaps = 20/187 (11%)

Query  16    ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQAR  75
              T   +  +   +  +    K   K +NV K E  +  +   KLEK  D     M+K   
Sbjct  4195  QTTLASLAEMDTDEMTPQERKIHIKRMNVLKQEIAKMESASLKLEKFLD----NMHKAEI  4250

Query  76    SEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI---IPLTTAAK----L  128
             S+  +  +   +  ML   L K+ N A   I      G + L     +      +    +
Sbjct  4251  SKRGKEDILLKVSNMLRLHLNKVANAAHCTI-QTPSAGLITLASAFDVHSLCVTQHSESV  4309

Query  129   MVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEI-SMDNSPNLAWPLIVT  187
             ++  PD +T+    D         ++      D   K +    + S DN     +P++ +
Sbjct  4310  LIQTPDDDTFLVYVD-------GQIYTCYNPTDITGKKLVPINVMSPDNVQFPTYPVVFS  4362

Query  188   ALRANSA  194
               + + A
Sbjct  4363  LSKQDYA  4369


>sp|Q008X5|R1A_WBV24 Replicase polyprotein 1a OS=White bream virus 
(isolate Blicca bjoerkna L./Germany/DF24/00) OX=766180 
GN=1a PE=1 SV=1
Length=4555

 Score = 36.6 bits (83),  Expect = 0.14, Method: Composition-based stats.
 Identities = 35/187 (19%), Positives = 66/187 (35%), Gaps = 20/187 (11%)

Query  16    ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQAR  75
              T   +  +   +  +    K   K +NV K E  +  +   KLEK  D     M+K   
Sbjct  4195  QTTLASLAEMDTDEMTPQERKIHIKRMNVLKQEIAKMESASLKLEKFLD----NMHKAEI  4250

Query  76    SEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI---IPLTTAAK----L  128
             S+  +  +   +  ML   L K+ N A   I      G + L     +      +    +
Sbjct  4251  SKRGKEDILLKVSNMLRLHLNKVANAAHCTI-QTPSAGLITLASAFDVHSLCVTQHSESV  4309

Query  129   MVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEI-SMDNSPNLAWPLIVT  187
             ++  PD +T+    D         ++      D   K +    + S DN     +P++ +
Sbjct  4310  LIQTPDDDTFLVYVD-------GQIYTCYNPTDITGKKLVPINVMSPDNVQFPTYPVVFS  4362

Query  188   ALRANSA  194
               + + A
Sbjct  4363  LSKQDYA  4369


>sp|O14261|ATG11_SCHPO Taz1-interacting factor 1 OS=Schizosaccharomyces 
pombe (strain 972 / ATCC 24843) OX=284812 GN=taf1 
PE=1 SV=2
Length=926

 Score = 33.9 bits (76),  Expect = 0.90, Method: Composition-based stats.
 Identities = 30/189 (16%), Positives = 75/189 (40%), Gaps = 23/189 (12%)

Query  26   VANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTS  85
            +A+  S+    K+ K L++     +  + +  +L    D+  T +     + +   +  S
Sbjct  100  IADSSSDQWKDKISKCLSLLSDILESSSKIHNQLSVCHDEYSTSIVSPEVAMNYLQRRQS  159

Query  86   AMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGT  145
             M+ +LF    +LD  ++++++++     +P   +P+T    L ++  ++    +  +  
Sbjct  160  GMKDLLFVFYERLDRVSVSDLLHDFL--ALPTGSLPITP---LKILSTNWTKLDSWLNSI  214

Query  146  TFTYASALWEIQQ------------------VVDADSKIVQLSEISMDNSPNLAWPLIVT  187
            +  YA A   +QQ                  + + D     L  ++ D +  L   L + 
Sbjct  215  SARYAEAQKRVQQCIGAANSIIVSPFKEVPSIKEGDDAYYHLRSVAQDAANILQEILKIE  274

Query  188  ALRANSAVK  196
            +    S +K
Sbjct  275  STSTTSQIK  283


>sp|Q9V1E9|KTHY_PYRAB Probable thymidylate kinase OS=Pyrococcus 
abyssi (strain GE5 / Orsay) OX=272844 GN=tmk PE=3 SV=1
Length=205

 Score = 33.1 bits (74),  Expect = 1.2, Method: Composition-based stats.
 Identities = 13/37 (35%), Positives = 22/37 (59%), Gaps = 1/37 (3%)

Query  47   SEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKV  83
            SEFD+   +QRK+ +M    + +M+K+ R  +  A V
Sbjct  152  SEFDKLLELQRKV-RMNYLKLAEMFKEMRIVNAMASV  187


>sp|A8G6V3|ATPF_PROM2 ATP synthase subunit b OS=Prochlorococcus 
marinus (strain MIT 9215) OX=93060 GN=atpF PE=3 SV=1
Length=170

 Score = 31.6 bits (70),  Expect = 2.7, Method: Composition-based stats.
 Identities = 19/104 (18%), Positives = 47/104 (45%), Gaps = 6/104 (6%)

Query  17   TAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQ---  73
             A +A E+A  +  S        K+ ++ +SE  R  + ++ +E+MA    + +  +   
Sbjct  64   NATQALEKAKKDLSSAEEKASQIKADSLKRSESIRMESEKKAIEEMARIKQSAISDESSE  123

Query  74   ---ARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGC  114
               A S+ ++  +  A++  L ++  +LD     N++  + +  
Sbjct  124  ASRAISQLRKEAIELAIKKALDSLPNRLDQTKQENLVTQSINNI  167


>sp|A6NGH8|ANR61_HUMAN Ankyrin repeat domain-containing protein 
61 OS=Homo sapiens OX=9606 GN=ANKRD61 PE=4 SV=2
Length=418

 Score = 32.3 bits (72),  Expect = 3.1, Method: Composition-based stats.
 Identities = 19/105 (18%), Positives = 45/105 (43%), Gaps = 7/105 (7%)

Query  85   SAMQTMLFTMLRKLDNDALNNIINNARDGCV--PLNIIPLTTAAKLMVVIPDYNTYKNTC  142
            +A+ + L+  + + D   +  ++   R+  V  P+ I+P + + +L++  P  +      
Sbjct  26   AALHSKLYEAIMREDCTTIEVLL---RNHPVNQPITILPNSASNRLLLTQPTESIIPIHL  82

Query  143  DGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVT  187
                    S L  ++    AD ++   + ++  N   L WP+  T
Sbjct  83   AAKYHKAQSLLCLLR--HGADPEVRDTTGLTTLNLMLLHWPVTST  125


>sp|A3PEU1|ATPF_PROM0 ATP synthase subunit b OS=Prochlorococcus 
marinus (strain MIT 9301) OX=167546 GN=atpF PE=3 SV=1
Length=170

 Score = 31.6 bits (70),  Expect = 3.3, Method: Composition-based stats.
 Identities = 20/104 (19%), Positives = 47/104 (45%), Gaps = 6/104 (6%)

Query  17   TAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQ---  73
             A +A E+A  +  S        K+ ++ +SE  R  + ++ +E+MA    + +  +   
Sbjct  64   NATQALEKAKKDLSSAEEKASQIKADSLKRSESIRMESEKKAIEEMARIKQSAISDESSE  123

Query  74   ---ARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGC  114
               A S+ ++  V  A++  L ++  +LD     N++  + +  
Sbjct  124  ASRAISQLRKEAVELAIKKALDSLPNRLDKTTQENLVTQSINNI  167


>sp|Q6NY52|THOC5_DANRE THO complex subunit 5 homolog OS=Danio 
rerio OX=7955 GN=thoc5 PE=2 SV=1
Length=684

 Score = 31.6 bits (70),  Expect = 4.7, Method: Composition-based stats.
 Identities = 20/95 (21%), Positives = 45/95 (47%), Gaps = 8/95 (8%)

Query  5    EFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMAD  64
            EF S        +  E ++ A A      V ++    L +A+ +++ D   QRK  ++A+
Sbjct  149  EFKSQHEEIELVSEDEFFQDAPAEISRPQVTREDHHQLTLARLDWELD---QRK--RLAE  203

Query  65   QAMTQMY---KQARSEDKRAKVTSAMQTMLFTMLR  96
            Q  T +    K  ++ +++ +  S++Q  L  +++
Sbjct  204  QYKTSLSSKEKIQKAIEQKREYLSSLQPGLHNIMQ  238


>sp|Q4FRM3|RS20_PSYA2 Small ribosomal subunit protein bS20 OS=Psychrobacter 
arcticus (strain DSM 17307 / VKM B-2377 / 273-4) 
OX=259536 GN=rpsT PE=3 SV=1
Length=88

 Score = 29.6 bits (65),  Expect = 6.2, Method: Composition-based stats.
 Identities = 18/82 (22%), Positives = 38/82 (46%), Gaps = 6/82 (7%)

Query  14  AFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQ--RK----LEKMADQAM  67
           A   A++  ++   +     +++   K ++ A +  D DAA +  +K    L++MAD+ +
Sbjct  7   ARKRARQNTKRRQNSASQRSMVRTYLKRVDAAIAAKDYDAATEAYKKAVPVLDRMADKGI  66

Query  68  TQMYKQARSEDKRAKVTSAMQT  89
               K AR + +  K    +Q 
Sbjct  67  LHKNKAARRKSRLNKTIKGLQA  88


>sp|A2BT27|ATPF_PROMS ATP synthase subunit b OS=Prochlorococcus 
marinus (strain AS9601) OX=146891 GN=atpF PE=3 SV=1
Length=170

 Score = 30.4 bits (67),  Expect = 7.1, Method: Composition-based stats.
 Identities = 20/104 (19%), Positives = 47/104 (45%), Gaps = 6/104 (6%)

Query  17   TAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQ---  73
             A +A E+A  +  S        K+ ++ +SE  R  + ++ +E+MA    + +  +   
Sbjct  64   NATQALEKAKKDLSSAAEKASQIKADSLKRSESIRMESEKKAIEEMARIKQSAISDESSE  123

Query  74   ---ARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGC  114
               A S+ ++  V  A++  L ++  +LD     N++  + +  
Sbjct  124  ASRAISQLRKEAVELAIKKALDSLPNRLDKTTQENLVTQSINNI  167



Lambda      K        H        a         alpha
   0.318    0.133    0.369    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0409    0.140     1.90     42.6     43.6 

Effective search space used: 12295187284

Search has CONVERGED!


  Database: uniprot_sprot.fasta
    Posted date:  Aug 1, 2024  3:29 PM
  Number of letters in database: 207,016,062
  Number of sequences in database:  571,864



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40