PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,282 sequences; 206,678,396 total letters
Results from round 1
Query= YP_009725302.1 nsp6 [Severe acute respiratory syndrome coronavirus
2]
Length=290
Score E
Sequences producing significant alignments: (Bits) Value
sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute resp... 602 0.0
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re... 600 0.0
sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus R... 540 3e-175
sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus H... 539 5e-175
sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respi... 539 6e-175
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus... 538 1e-174
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus... 538 1e-174
sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus 2... 538 2e-174
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res... 538 2e-174
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus... 536 7e-174
sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus H... 173 2e-47
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus... 173 2e-47
sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respi... 167 2e-45
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res... 167 3e-45
sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus H... 160 5e-43
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus... 160 7e-43
sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus 1... 155 4e-41
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus... 155 4e-41
sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus H... 151 6e-40
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus... 151 1e-39
sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus... 137 4e-35
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir... 137 8e-35
sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronaviru... 133 1e-33
sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronaviru... 133 1e-33
sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronaviru... 133 2e-33
sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus... 133 2e-33
sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus... 132 2e-33
sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus... 132 2e-33
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi... 132 2e-33
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir... 132 2e-33
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi... 132 3e-33
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi... 132 3e-33
sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus... 132 3e-33
sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronaviru... 132 3e-33
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir... 132 4e-33
sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus... 132 4e-33
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir... 132 4e-33
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi... 131 5e-33
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir... 131 5e-33
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir... 131 6e-33
sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus... 127 2e-31
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir... 126 3e-31
sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic ... 97.1 3e-21
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi... 96.7 5e-21
sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus... 92.0 2e-19
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir... 91.7 3e-19
sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus... 90.5 7e-19
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir... 90.1 9e-19
sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmiss... 81.3 7e-16
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi... 81.3 8e-16
sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus 5... 80.5 1e-15
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus... 80.1 2e-15
sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious b... 74.7 1e-13
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir... 74.3 2e-13
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious... 73.9 2e-13
sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious ... 73.2 4e-13
sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious b... 73.2 4e-13
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou... 72.8 6e-13
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious... 72.8 6e-13
sp|Q9VHM2|VP35L_DROME VPS35 endosomal protein sorting factor-like... 39.3 0.039
sp|Q9DCS1|T176A_MOUSE Transmembrane protein 176A OS=Mus musculus ... 33.1 2.4
>sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 PE=1 SV=1
Length=4405
Score = 602 bits (1553), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 290/290 (100%), Positives = 290/290 (100%), Gaps = 0/290 (0%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV
Sbjct 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV 120
KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV
Sbjct 3630 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV 3689
Query 121 VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT 180
VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT
Sbjct 3690 VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT 3749
Query 181 TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG 240
TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG
Sbjct 3750 TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG 3809
Query 241 VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ
Sbjct 3810 VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 3859
>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1
SV=1
Length=7096
Score = 600 bits (1546), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 290/290 (100%), Positives = 290/290 (100%), Gaps = 0/290 (0%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV
Sbjct 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV 120
KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV
Sbjct 3630 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV 3689
Query 121 VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT 180
VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT
Sbjct 3690 VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT 3749
Query 181 TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG 240
TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG
Sbjct 3750 TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG 3809
Query 241 VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ
Sbjct 3810 VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 3859
>sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus
Rp3/2004 OX=349344 GN=1a PE=3 SV=1
Length=4380
Score = 540 bits (1391), Expect = 3e-175, Method: Compositional matrix adjust.
Identities = 253/287 (88%), Positives = 275/287 (96%), Gaps = 0/287 (0%)
Query 4 KRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHK 63
KR +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHK
Sbjct 3548 KRIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAVAACAMLLVKHK 3607
Query 64 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLL 123
HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL
Sbjct 3608 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLL 3667
Query 124 ILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVM 183
+LMTARTVYDD ARRVWTLMNV+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+M
Sbjct 3668 VLMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIM 3727
Query 184 FLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYD 243
FLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYD
Sbjct 3728 FLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYD 3787
Query 244 YLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3788 YLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3834
>sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus
HKU3 OX=442736 GN=1a PE=3 SV=1
Length=4376
Score = 539 bits (1389), Expect = 5e-175, Method: Compositional matrix adjust.
Identities = 253/287 (88%), Positives = 276/287 (96%), Gaps = 0/287 (0%)
Query 4 KRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHK 63
K+ +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPFA+GI+A++A AM+ VKHK
Sbjct 3544 KKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFALGIMAVAACAMLLVKHK 3603
Query 64 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLL 123
HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL
Sbjct 3604 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLL 3663
Query 124 ILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVM 183
ILMTARTVYDD ARRVWTLMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+M
Sbjct 3664 ILMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIM 3723
Query 184 FLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYD 243
FLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYD
Sbjct 3724 FLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYD 3783
Query 244 YLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3784 YLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3830
>sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respiratory
syndrome coronavirus OX=694009 GN=1a PE=1 SV=1
Length=4382
Score = 539 bits (1389), Expect = 6e-175, Method: Compositional matrix adjust.
Identities = 253/287 (88%), Positives = 275/287 (96%), Gaps = 0/287 (0%)
Query 4 KRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHK 63
K+ +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHK
Sbjct 3550 KKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHK 3609
Query 64 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLL 123
HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL
Sbjct 3610 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLL 3669
Query 124 ILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVM 183
ILMTARTVYDD ARRVWTLMNV+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+M
Sbjct 3670 ILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIM 3729
Query 184 FLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYD 243
FLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYD
Sbjct 3730 FLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYD 3789
Query 244 YLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3790 YLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3836
>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071
Score = 538 bits (1386), Expect = 1e-174, Method: Compositional matrix adjust.
Identities = 253/287 (88%), Positives = 275/287 (96%), Gaps = 0/287 (0%)
Query 4 KRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHK 63
KR +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHK
Sbjct 3548 KRIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAVAACAMLLVKHK 3607
Query 64 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLL 123
HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL
Sbjct 3608 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLL 3667
Query 124 ILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVM 183
+LMTARTVYDD ARRVWTLMNV+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+M
Sbjct 3668 VLMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIM 3727
Query 184 FLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYD 243
FLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYD
Sbjct 3728 FLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYD 3787
Query 244 YLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3788 YLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3834
>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067
Score = 538 bits (1386), Expect = 1e-174, Method: Compositional matrix adjust.
Identities = 253/287 (88%), Positives = 276/287 (96%), Gaps = 0/287 (0%)
Query 4 KRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHK 63
K+ +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPFA+GI+A++A AM+ VKHK
Sbjct 3544 KKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFALGIMAVAACAMLLVKHK 3603
Query 64 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLL 123
HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL
Sbjct 3604 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLL 3663
Query 124 ILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVM 183
ILMTARTVYDD ARRVWTLMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+M
Sbjct 3664 ILMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIM 3723
Query 184 FLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYD 243
FLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYD
Sbjct 3724 FLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYD 3783
Query 244 YLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3784 YLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3830
>sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus
279/2005 OX=389167 GN=1a PE=3 SV=1
Length=4388
Score = 538 bits (1385), Expect = 2e-174, Method: Compositional matrix adjust.
Identities = 251/287 (87%), Positives = 275/287 (96%), Gaps = 0/287 (0%)
Query 4 KRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHK 63
K+ +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHK
Sbjct 3556 KKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHK 3615
Query 64 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLL 123
HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL
Sbjct 3616 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLL 3675
Query 124 ILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVM 183
+LMTARTVYDD ARRVWTLMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+M
Sbjct 3676 VLMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIM 3735
Query 184 FLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYD 243
FLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYD
Sbjct 3736 FLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYD 3795
Query 244 YLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3796 YLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3842
>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score = 538 bits (1385), Expect = 2e-174, Method: Compositional matrix adjust.
Identities = 253/287 (88%), Positives = 275/287 (96%), Gaps = 0/287 (0%)
Query 4 KRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHK 63
K+ +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHK
Sbjct 3550 KKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHK 3609
Query 64 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLL 123
HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL
Sbjct 3610 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLL 3669
Query 124 ILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVM 183
ILMTARTVYDD ARRVWTLMNV+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+M
Sbjct 3670 ILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIM 3729
Query 184 FLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYD 243
FLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYD
Sbjct 3730 FLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYD 3789
Query 244 YLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3790 YLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3836
>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079
Score = 536 bits (1381), Expect = 7e-174, Method: Compositional matrix adjust.
Identities = 251/287 (87%), Positives = 275/287 (96%), Gaps = 0/287 (0%)
Query 4 KRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHK 63
K+ +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHK
Sbjct 3556 KKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHK 3615
Query 64 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLL 123
HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL
Sbjct 3616 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLL 3675
Query 124 ILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVM 183
+LMTARTVYDD ARRVWTLMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+M
Sbjct 3676 VLMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIM 3735
Query 184 FLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYD 243
FLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYD
Sbjct 3736 FLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYD 3795
Query 244 YLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3796 YLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3842
>sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus
HKU9 OX=694006 GN=1a PE=3 SV=1
Length=4248
Score = 173 bits (439), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 100/282 (35%), Positives = 155/282 (55%), Gaps = 2/282 (1%)
Query 10 THHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMS-AFAMMFVKHKHAFLC 68
T W + + ++L+L+Q QW+ L LP +G +A+ F + +KHKH +L
Sbjct 3419 TLQWFAIIFVLTILILLQLAQWTFVGALPFTLLLPL-IGFVAVCVGFVSLLIKHKHTYLT 3477
Query 69 LFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTA 128
++LLP AY+N Y P +++ + V+ D + V L++
Sbjct 3478 VYLLPVAMVTAYYNFQYTPEGVQGYLLSLYNYVNPGRIDVIGTDLLTMLIISVACTLLSV 3537
Query 129 RTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARG 188
R V D R+W + + +Y + G+A AIS ++SV +NY+GV ++ A+
Sbjct 3538 RMVRTDAYSRIWYVCTAVGWLYNCWTGSADTVAISYLTFMVSVFTNYTGVACASLYAAQF 3597
Query 189 IVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVST 248
+V++ P + +C+++ Y +GY CTCYFG+F L+NR FR TLG Y+Y+VS+
Sbjct 3598 MVWVLKFLDPTILLLYGRFRCVLVCYLLVGYLCTCYFGVFNLINRLFRCTLGNYEYVVSS 3657
Query 249 QEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
QE RYMNS GLLPP NS A LNIKL G+GG P +V+T+Q
Sbjct 3658 QELRYMNSHGLLPPTNSWQALMLNIKLAGIGGIPIYRVSTIQ 3699
>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930
Score = 173 bits (438), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 100/282 (35%), Positives = 155/282 (55%), Gaps = 2/282 (1%)
Query 10 THHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMS-AFAMMFVKHKHAFLC 68
T W + + ++L+L+Q QW+ L LP +G +A+ F + +KHKH +L
Sbjct 3419 TLQWFAIIFVLTILILLQLAQWTFVGALPFTLLLPL-IGFVAVCVGFVSLLIKHKHTYLT 3477
Query 69 LFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTA 128
++LLP AY+N Y P +++ + V+ D + V L++
Sbjct 3478 VYLLPVAMVTAYYNFQYTPEGVQGYLLSLYNYVNPGRIDVIGTDLLTMLIISVACTLLSV 3537
Query 129 RTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARG 188
R V D R+W + + +Y + G+A AIS ++SV +NY+GV ++ A+
Sbjct 3538 RMVRTDAYSRIWYVCTAVGWLYNCWTGSADTVAISYLTFMVSVFTNYTGVACASLYAAQF 3597
Query 189 IVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVST 248
+V++ P + +C+++ Y +GY CTCYFG+F L+NR FR TLG Y+Y+VS+
Sbjct 3598 MVWVLKFLDPTILLLYGRFRCVLVCYLLVGYLCTCYFGVFNLINRLFRCTLGNYEYVVSS 3657
Query 249 QEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
QE RYMNS GLLPP NS A LNIKL G+GG P +V+T+Q
Sbjct 3658 QELRYMNSHGLLPPTNSWQALMLNIKLAGIGGIPIYRVSTIQ 3699
>sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respiratory
syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=1a PE=1 SV=1
Length=4391
Score = 167 bits (424), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 104/297 (35%), Positives = 168/297 (57%), Gaps = 12/297 (4%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLP---FAMGIIAMSAFAM 57
S V++ GT HWL T++++ ++++Q+T+++L+ +L+E +P F + + M AF M
Sbjct 3554 SGVRKVTYGTAHWLFATLVSTYVIILQATKFTLWNYLFET--IPTQLFPLLFVTM-AFVM 3610
Query 58 MFVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDC 113
+ VKHKH FL LFLLP + Y N+VY P +S ++ + WL + + D
Sbjct 3611 LLVKHKHTFLTLFLLPVAICLTYANIVYEPTTPISSALIAVANWLAPTNAYMRTTHT-DI 3669
Query 114 VMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTS 173
+Y S ++L+++ R + L + + +Y G A I+ + ++TS
Sbjct 3670 GVYISMSLVLVIVVKRLYNPSLSNFALALCSGVMWLYTYSIGEA-SSPIAYLVFVTTLTS 3728
Query 174 NYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNR 233
+Y+ V + LA+ + Y P + ++ I+L+Y LG+ CTCYFG+F LLN
Sbjct 3729 DYTITVFVTVNLAKVCTYAIFAYSPQLTLVFPEVKMILLLYTCLGFMCTCYFGVFSLLNL 3788
Query 234 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
R +GVYD+ VSTQEFR+M + L P+NS +A LN KL+G+GG PCIKVA +Q
Sbjct 3789 KLRAPMGVYDFKVSTQEFRFMTANNLTAPRNSWEAMALNFKLIGIGGTPCIKVAAMQ 3845
>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=rep PE=1 SV=1
Length=7078
Score = 167 bits (422), Expect = 3e-45, Method: Compositional matrix adjust.
Identities = 104/297 (35%), Positives = 168/297 (57%), Gaps = 12/297 (4%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLP---FAMGIIAMSAFAM 57
S V++ GT HWL T++++ ++++Q+T+++L+ +L+E +P F + + M AF M
Sbjct 3554 SGVRKVTYGTAHWLFATLVSTYVIILQATKFTLWNYLFET--IPTQLFPLLFVTM-AFVM 3610
Query 58 MFVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDC 113
+ VKHKH FL LFLLP + Y N+VY P +S ++ + WL + + D
Sbjct 3611 LLVKHKHTFLTLFLLPVAICLTYANIVYEPTTPISSALIAVANWLAPTNAYMRTTHT-DI 3669
Query 114 VMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTS 173
+Y S ++L+++ R + L + + +Y G A I+ + ++TS
Sbjct 3670 GVYISMSLVLVIVVKRLYNPSLSNFALALCSGVMWLYTYSIGEA-SSPIAYLVFVTTLTS 3728
Query 174 NYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNR 233
+Y+ V + LA+ + Y P + ++ I+L+Y LG+ CTCYFG+F LLN
Sbjct 3729 DYTITVFVTVNLAKVCTYAIFAYSPQLTLVFPEVKMILLLYTCLGFMCTCYFGVFSLLNL 3788
Query 234 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
R +GVYD+ VSTQEFR+M + L P+NS +A LN KL+G+GG PCIKVA +Q
Sbjct 3789 KLRAPMGVYDFKVSTQEFRFMTANNLTAPRNSWEAMALNFKLIGIGGTPCIKVAAMQ 3845
>sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus
HKU5 OX=694008 GN=1a PE=3 SV=1
Length=4481
Score = 160 bits (405), Expect = 5e-43, Method: Compositional matrix adjust.
Identities = 104/298 (35%), Positives = 163/298 (55%), Gaps = 14/298 (5%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S VKR G HWL T+L + + +Q T+++++ +L+E L ++ + A M+ V
Sbjct 3645 SGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLTPLVLCVMACVMLTV 3704
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH FL LFLLP+ + Y N+VY P +S ++ + WL+ + D +Y
Sbjct 3705 KHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPASVYMRTTHT-DLGVY 3763
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S L ++ R + + L + + Y G+ ++ + ++TS+Y+
Sbjct 3764 LSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPLTYLMFLTTLTSDYT 3822
Query 177 G----VVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLN 232
V F AR +VF+ + F ++ ++L+Y +GYFCT YFG+F LLN
Sbjct 3823 VTVFLAVNVAKFFAR-VVFLYAPHAGFIFPE---VKLVLLMYLAVGYFCTVYFGVFSLLN 3878
Query 233 RYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
R+ LGVYDY VSTQEFRY+ GL P+NS +A +LN+KL+G+GG PCIK+A+VQ
Sbjct 3879 LKLRVPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTPCIKIASVQ 3936
>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182
Score = 160 bits (404), Expect = 7e-43, Method: Compositional matrix adjust.
Identities = 104/298 (35%), Positives = 163/298 (55%), Gaps = 14/298 (5%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S VKR G HWL T+L + + +Q T+++++ +L+E L ++ + A M+ V
Sbjct 3645 SGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLTPLVLCVMACVMLTV 3704
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH FL LFLLP+ + Y N+VY P +S ++ + WL+ + D +Y
Sbjct 3705 KHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPASVYMRTTHT-DLGVY 3763
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S L ++ R + + L + + Y G+ ++ + ++TS+Y+
Sbjct 3764 LSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPLTYLMFLTTLTSDYT 3822
Query 177 G----VVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLN 232
V F AR +VF+ + F ++ ++L+Y +GYFCT YFG+F LLN
Sbjct 3823 VTVFLAVNVAKFFAR-VVFLYAPHAGFIFPE---VKLVLLMYLAVGYFCTVYFGVFSLLN 3878
Query 233 RYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
R+ LGVYDY VSTQEFRY+ GL P+NS +A +LN+KL+G+GG PCIK+A+VQ
Sbjct 3879 LKLRVPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTPCIKIASVQ 3936
>sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus
133/2005 OX=389230 GN=1a PE=3 SV=1
Length=4441
Score = 155 bits (391), Expect = 4e-41, Method: Compositional matrix adjust.
Identities = 108/297 (36%), Positives = 159/297 (54%), Gaps = 12/297 (4%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S VKR G HWL+ T++ + + ++Q T+++++ +L+E + A M V
Sbjct 3605 SGVKRISYGFMHWLMSTLVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLFGFMACVMFTV 3664
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH FL LFLLP + Y N+VY P +S ++ + WL + L D +Y
Sbjct 3665 KHKHTFLSLFLLPVALCLTYANIVYEPQTLVSSTLIAVANWLTPTSVYMRTTHL-DFGLY 3723
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S +L ++ R + L + + Y G+ I+ I ++TS+Y+
Sbjct 3724 ISLSFVLAIIVRRLYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYT 3782
Query 177 GVVTTVMFLAR---GIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNR 233
V + LA+ G+VF+ Y P ++ ++L+Y LGY CT YFG+F LLN
Sbjct 3783 ITVFATVNLAKFISGLVFL---YAPHLGFILPEVKLVLLIYLCLGYMCTMYFGVFSLLNL 3839
Query 234 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
R+ LGVYDY VSTQEFR++ GL P+NS +A LN KLLG+GG PCIKVATVQ
Sbjct 3840 KLRVPLGVYDYSVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQ 3896
>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126
Score = 155 bits (391), Expect = 4e-41, Method: Compositional matrix adjust.
Identities = 108/297 (36%), Positives = 159/297 (54%), Gaps = 12/297 (4%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S VKR G HWL+ T++ + + ++Q T+++++ +L+E + A M V
Sbjct 3605 SGVKRISYGFMHWLMSTLVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLFGFMACVMFTV 3664
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH FL LFLLP + Y N+VY P +S ++ + WL + L D +Y
Sbjct 3665 KHKHTFLSLFLLPVALCLTYANIVYEPQTLVSSTLIAVANWLTPTSVYMRTTHL-DFGLY 3723
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S +L ++ R + L + + Y G+ I+ I ++TS+Y+
Sbjct 3724 ISLSFVLAIIVRRLYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYT 3782
Query 177 GVVTTVMFLAR---GIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNR 233
V + LA+ G+VF+ Y P ++ ++L+Y LGY CT YFG+F LLN
Sbjct 3783 ITVFATVNLAKFISGLVFL---YAPHLGFILPEVKLVLLIYLCLGYMCTMYFGVFSLLNL 3839
Query 234 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
R+ LGVYDY VSTQEFR++ GL P+NS +A LN KLLG+GG PCIKVATVQ
Sbjct 3840 KLRVPLGVYDYSVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQ 3896
>sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus
HKU4 OX=694007 GN=1a PE=1 SV=1
Length=4434
Score = 151 bits (382), Expect = 6e-40, Method: Compositional matrix adjust.
Identities = 104/294 (35%), Positives = 155/294 (53%), Gaps = 6/294 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S VKR G HWL+ T + + + ++Q T+++++ +L+E ++ A M V
Sbjct 3598 SGVKRISYGFIHWLISTFVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLLGFMACVMFTV 3657
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH F+ LFLLP + Y N+VY P +S ++ + WL + D +Y
Sbjct 3658 KHKHTFMSLFLLPVALCLTYANIVYEPQTLISSTLIAVANWLTPTSVYMRTTHF-DFGLY 3716
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S +L ++ R + L + + Y G+ I+ I ++TS+Y+
Sbjct 3717 ISLSFVLAIIVRRLYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYT 3775
Query 177 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 236
V + LA+ I + Y P ++ ++L+Y LGY CT YFG+F LLN R
Sbjct 3776 ITVFATVNLAKFISGLVFFYAPHLGFILPEVKLVLLIYLGLGYMCTMYFGVFSLLNLKLR 3835
Query 237 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+ LGVYDY VSTQEFR++ GL P+NS +A LN KLLG+GG PCIKVATVQ
Sbjct 3836 VPLGVYDYSVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQ 3889
>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119
Score = 151 bits (381), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 104/294 (35%), Positives = 155/294 (53%), Gaps = 6/294 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S VKR G HWL+ T + + + ++Q T+++++ +L+E ++ A M V
Sbjct 3598 SGVKRISYGFIHWLISTFVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLLGFMACVMFTV 3657
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH F+ LFLLP + Y N+VY P +S ++ + WL + D +Y
Sbjct 3658 KHKHTFMSLFLLPVALCLTYANIVYEPQTLISSTLIAVANWLTPTSVYMRTTHF-DFGLY 3716
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S +L ++ R + L + + Y G+ I+ I ++TS+Y+
Sbjct 3717 ISLSFVLAIIVRRLYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYT 3775
Query 177 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 236
V + LA+ I + Y P ++ ++L+Y LGY CT YFG+F LLN R
Sbjct 3776 ITVFATVNLAKFISGLVFFYAPHLGFILPEVKLVLLIYLGLGYMCTMYFGVFSLLNLKLR 3835
Query 237 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+ LGVYDY VSTQEFR++ GL P+NS +A LN KLLG+GG PCIKVATVQ
Sbjct 3836 VPLGVYDYSVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQ 3889
>sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus
(strain 2) OX=76344 GN=1a PE=3 SV=1
Length=4416
Score = 137 bits (346), Expect = 4e-35, Method: Compositional matrix adjust.
Identities = 99/297 (33%), Positives = 166/297 (56%), Gaps = 17/297 (6%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KGT W+L + L ++ +W++F ++ + L + + +FAM+ V
Sbjct 3583 SKRTRVVKGTCCWILASTLLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLV 3641
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L +F++P L T+ Y N +V S+ WL ++ + D V+Y
Sbjct 3642 KHKHLYLTMFIMPVLCTLFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLYG-- 3698
Query 120 VVLLILM---TARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
VVLL+ M T R++ D ++ + +++LV Y+G L++ + ++ + S+ Y+
Sbjct 3699 VVLLVAMVFVTMRSINHDVFSVMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYT 3756
Query 177 GVVTTVMFLARGIV---FMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNR 233
TT++ LA V ++ V ++F ++ ++L Y +GY C CY+G+ LLN
Sbjct 3757 W--TTMLSLATAKVIAKWLAVNV--LYFTDVPQVKLVLLSYLCIGYVCCCYWGVLSLLNS 3812
Query 234 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
FR+ LGVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +Q
Sbjct 3813 IFRMPLGVYNYKISVQELRYMNANGLRPPRNSFEALVLNFKLLGIGGVPVIEVSQIQ 3869
>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124
Score = 137 bits (344), Expect = 8e-35, Method: Compositional matrix adjust.
Identities = 99/297 (33%), Positives = 166/297 (56%), Gaps = 17/297 (6%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KGT W+L + L ++ +W++F ++ + L + + +FAM+ V
Sbjct 3583 SKRTRVVKGTCCWILASTLLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLV 3641
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L +F++P L T+ Y N +V S+ WL ++ + D V+Y
Sbjct 3642 KHKHLYLTMFIMPVLCTLFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLYG-- 3698
Query 120 VVLLILM---TARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
VVLL+ M T R++ D ++ + +++LV Y+G L++ + ++ + S+ Y+
Sbjct 3699 VVLLVAMVFVTMRSINHDVFSVMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYT 3756
Query 177 GVVTTVMFLARGIV---FMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNR 233
TT++ LA V ++ V ++F ++ ++L Y +GY C CY+G+ LLN
Sbjct 3757 W--TTMLSLATAKVIAKWLAVNV--LYFTDVPQVKLVLLSYLCIGYVCCCYWGVLSLLNS 3812
Query 234 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
FR+ LGVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +Q
Sbjct 3813 IFRMPLGVYNYKISVQELRYMNANGLRPPRNSFEALVLNFKLLGIGGVPVIEVSQIQ 3869
>sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronavirus
(strain JHM) OX=11144 GN=1a PE=1 SV=1
Length=4474
Score = 133 bits (334), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 96/298 (32%), Positives = 164/298 (55%), Gaps = 18/298 (6%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R IKGT W+L + ++ +W++F ++ + L + + FAM+ +
Sbjct 3640 SKRTRVIKGTCCWILASTFLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVIFAMLLI 3698
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMT--WLDMVDTSLSGFKLKDCVMYAS 118
KHKH +L ++++P L T+ Y N + + R + WL ++ + D V+Y
Sbjct 3699 KHKHLYLTMYIMPVLCTLFYTNYLVVGYKQSFRGLAYAWLSYFVPAVD-YTYMDEVLYG- 3756
Query 119 AVVLLILM---TARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNY 175
VVLL+ M T R++ D ++ + +++LV Y+G L++ + ++ + S+ Y
Sbjct 3757 -VVLLVAMVFVTMRSINHDVFSTMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTY 3813
Query 176 SGVVTTVMFLARGIV---FMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLN 232
+ TT++ LA V ++ V ++F ++ ++L Y +GY C CY+G+ LLN
Sbjct 3814 TW--TTMLSLATAKVIAKWLAVNV--LYFTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLN 3869
Query 233 RYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
FR+ LGVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +Q
Sbjct 3870 SIFRMPLGVYNYKISVQELRYMNANGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQ 3927
>sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=1a PE=3 SV=1
Length=4383
Score = 133 bits (334), Expect = 1e-33, Method: Compositional matrix adjust.
Identities = 89/292 (30%), Positives = 160/292 (55%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + AM+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=1a PE=3 SV=1
Length=4383
Score = 133 bits (334), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 89/292 (30%), Positives = 160/292 (55%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + AM+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=1a PE=3 SV=1
Length=4383
Score = 133 bits (334), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 89/292 (30%), Positives = 160/292 (55%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + AM+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=1a PE=3 SV=1
Length=4421
Score = 132 bits (333), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 89/292 (30%), Positives = 159/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3588 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3646
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3647 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYEVFYGCIL 3706
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3707 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3762
Query 180 TTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3763 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3822
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +Q
Sbjct 3823 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQ 3874
>sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=1a PE=3 SV=1
Length=4441
Score = 132 bits (333), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 89/292 (30%), Positives = 159/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3608 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3666
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3667 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGLTYVWLSYFVPAVNFTYVYEVFYGCIL 3726
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3727 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3782
Query 180 TTVMFLARGIVFMCVEYCPIFFITGNT-LQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3783 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3842
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +Q
Sbjct 3843 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQ 3894
>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180
Score = 132 bits (333), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 96/298 (32%), Positives = 164/298 (55%), Gaps = 18/298 (6%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R IKGT W+L + ++ +W++F ++ + L + + FAM+ +
Sbjct 3640 SKRTRVIKGTCCWILASTFLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVIFAMLLI 3698
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMT--WLDMVDTSLSGFKLKDCVMYAS 118
KHKH +L ++++P L T+ Y N + + R + WL ++ + D V+Y
Sbjct 3699 KHKHLYLTMYIMPVLCTLFYTNYLVVGYKQSFRGLAYAWLSYFVPAVD-YTYMDEVLYG- 3756
Query 119 AVVLLILM---TARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNY 175
VVLL+ M T R++ D ++ + +++LV Y+G L++ + ++ + S+ Y
Sbjct 3757 -VVLLVAMVFVTMRSINHDVFSTMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTY 3813
Query 176 SGVVTTVMFLARGIV---FMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLN 232
+ TT++ LA V ++ V ++F ++ ++L Y +GY C CY+G+ LLN
Sbjct 3814 TW--TTMLSLATAKVIAKWLAVNV--LYFTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLN 3869
Query 233 RYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
FR+ LGVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +Q
Sbjct 3870 SIFRMPLGVYNYKISVQELRYMNANGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQ 3927
>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059
Score = 132 bits (333), Expect = 2e-33, Method: Compositional matrix adjust.
Identities = 89/292 (30%), Positives = 160/292 (55%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + AM+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094
Score = 132 bits (332), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 89/292 (30%), Positives = 160/292 (55%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + AM+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094
Score = 132 bits (332), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 89/292 (30%), Positives = 160/292 (55%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + AM+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus
OC43 OX=31631 GN=1a PE=1 SV=1
Length=4383
Score = 132 bits (332), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 97/297 (33%), Positives = 166/297 (56%), Gaps = 17/297 (6%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAF-LPF-AMGIIAMSAFAMM 58
S R KGT W++ + ++ +W++F ++ N F + F A+ +I++ AM+
Sbjct 3550 SKRTRLFKGTVCWIMASTFLFSCIITAFVKWTMFMYVTTNMFSITFCALCVISL---AML 3606
Query 59 FVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYA 117
VKHKH +L +++ P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3607 LVKHKHLYLTMYITPVLFTLLYNNYLVVYKHTFRGYVYAWLSYYVPSVE-YTYTDEVIYG 3665
Query 118 SAVVL-LILMTARTVYDD---GARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTS 173
+++ ++ +T R++ D V L++V +L YK G+ L++ I + ++ S+
Sbjct 3666 MLLLVGMVFVTLRSINHDLFSFIMFVGRLISVFSLWYK---GSNLEEEILL--MLASLFG 3720
Query 174 NYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNR 233
Y+ M +A+ ++ V ++F ++ ++L Y F+GY +CY+GLF L+N
Sbjct 3721 TYTWTTVLSMAVAK-VIAKWVAVNVLYFTDIPQIKIVLLCYLFIGYIISCYWGLFSLMNS 3779
Query 234 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3780 LFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronavirus
(strain A59) OX=11142 GN=1a PE=1 SV=1
Length=4468
Score = 132 bits (332), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 95/296 (32%), Positives = 162/296 (55%), Gaps = 16/296 (5%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R IKGT W+L + ++ +W++F ++ + L + + +FAM+ +
Sbjct 3636 SKRTRVIKGTCCWILASTFLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLI 3694
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV 120
KHKH +L ++++P L T +V S+ WL ++ + D V+Y V
Sbjct 3695 KHKHLYLTMYIMPVLCTFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLYG--V 3751
Query 121 VLLILM---TARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSG 177
VLL+ M T R++ D ++ + +++LV Y+G L++ + ++ + S+ Y+
Sbjct 3752 VLLVAMVFVTMRSINHDVFSIMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW 3809
Query 178 VVTTVMFLARGIV---FMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 234
TT++ LA V ++ V ++F ++ ++L Y +GY C CY+G+ LLN
Sbjct 3810 --TTMLSLATAKVIAKWLAVNV--LYFTDVPQIKLVLLSYLCIGYVCCCYWGILSLLNSI 3865
Query 235 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
FR+ LGVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +Q
Sbjct 3866 FRMPLGVYNYKISVQELRYMNANGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQ 3921
>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132
Score = 132 bits (331), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 89/292 (30%), Positives = 159/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3588 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3646
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3647 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYEVFYGCIL 3706
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3707 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3762
Query 180 TTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3763 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3822
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +Q
Sbjct 3823 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQ 3874
>sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=1a PE=1 SV=1
Length=4471
Score = 132 bits (331), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 89/292 (30%), Positives = 159/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3638 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3696
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3697 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSYFVPAVNFTYVYEVFYGCIL 3756
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3757 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3812
Query 180 TTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3813 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3872
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +Q
Sbjct 3873 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQ 3924
>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152
Score = 132 bits (331), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 89/292 (30%), Positives = 159/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3608 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3666
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3667 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGLTYVWLSYFVPAVNFTYVYEVFYGCIL 3726
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3727 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3782
Query 180 TTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3783 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3842
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +Q
Sbjct 3843 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQ 3894
>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176
Score = 131 bits (330), Expect = 5e-33, Method: Compositional matrix adjust.
Identities = 95/296 (32%), Positives = 162/296 (55%), Gaps = 16/296 (5%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R IKGT W+L + ++ +W++F ++ + L + + +FAM+ +
Sbjct 3636 SKRTRVIKGTCCWILASTFLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLI 3694
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV 120
KHKH +L ++++P L T +V S+ WL ++ + D V+Y V
Sbjct 3695 KHKHLYLTMYIMPVLCTFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLYG--V 3751
Query 121 VLLILM---TARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSG 177
VLL+ M T R++ D ++ + +++LV Y+G L++ + ++ + S+ Y+
Sbjct 3752 VLLVAMVFVTMRSINHDVFSIMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW 3809
Query 178 VVTTVMFLARGIV---FMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 234
TT++ LA V ++ V ++F ++ ++L Y +GY C CY+G+ LLN
Sbjct 3810 --TTMLSLATAKVIAKWLAVNV--LYFTDVPQIKLVLLSYLCIGYVCCCYWGILSLLNSI 3865
Query 235 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
FR+ LGVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +Q
Sbjct 3866 FRMPLGVYNYKISVQELRYMNANGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQ 3921
>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095
Score = 131 bits (330), Expect = 5e-33, Method: Compositional matrix adjust.
Identities = 97/297 (33%), Positives = 166/297 (56%), Gaps = 17/297 (6%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAF-LPF-AMGIIAMSAFAMM 58
S R KGT W++ + ++ +W++F ++ N F + F A+ +I++ AM+
Sbjct 3550 SKRTRLFKGTVCWIMASTFLFSCIITAFVKWTMFMYVTTNMFSITFCALCVISL---AML 3606
Query 59 FVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYA 117
VKHKH +L +++ P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3607 LVKHKHLYLTMYITPVLFTLLYNNYLVVYKHTFRGYVYAWLSYYVPSVE-YTYTDEVIYG 3665
Query 118 SAVVL-LILMTARTVYDDGARR---VWTLMNVLTLVYKVYYGNALDQAISMWALIISVTS 173
+++ ++ +T R++ D V L++V +L YK G+ L++ I + ++ S+
Sbjct 3666 MLLLVGMVFVTLRSINHDLFSFIMFVGRLISVFSLWYK---GSNLEEEILL--MLASLFG 3720
Query 174 NYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNR 233
Y+ M +A+ ++ V ++F ++ ++L Y F+GY +CY+GLF L+N
Sbjct 3721 TYTWTTVLSMAVAK-VIAKWVAVNVLYFTDIPQIKIVLLCYLFIGYIISCYWGLFSLMNS 3779
Query 234 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3780 LFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182
Score = 131 bits (330), Expect = 6e-33, Method: Compositional matrix adjust.
Identities = 89/292 (30%), Positives = 159/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3638 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3696
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3697 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSYFVPAVNFTYVYEVFYGCIL 3756
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3757 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3812
Query 180 TTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3813 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3872
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +Q
Sbjct 3873 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQ 3924
>sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=1a PE=3 SV=1
Length=4383
Score = 127 bits (319), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 87/292 (30%), Positives = 158/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + M+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLTMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ + + V+++V Y G+ L++ I + ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINQYLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094
Score = 126 bits (317), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 87/292 (30%), Positives = 158/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + M+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLTMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ + + V+++V Y G+ L++ I + ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINQYLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=1a PE=1 SV=1
Length=4117
Score = 97.1 bits (240), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 76/239 (32%), Positives = 124/239 (52%), Gaps = 17/239 (7%)
Query 57 MMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL-DMVD--TSLSGFKLKDC 113
M +KHK F +FL+P+L + N+ + + + +L + D SL GF +
Sbjct 3353 MFTLKHKTLFFQVFLIPALIVTSCINLAFD-----VEVYNYLAEHFDYHVSLMGFNAQGL 3407
Query 114 VMYASAVVLLILMTART--VYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISV 171
V V+ IL T ++ A V ++ +LT Y +Y A D L SV
Sbjct 3408 VNIFVCFVVTILHGTYTWRFFNTPASSVTYVVALLTAAYNYFY--ASDILSCAMTLFASV 3465
Query 172 TSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLL 231
T N+ V V + + V+M + + P F ++ +M Y LGYF C++G+
Sbjct 3466 TGNW--FVGAVCY--KVAVYMALRF-PTFVAIFGDIKSVMFCYLVLGYFTCCFYGILYWF 3520
Query 232 NRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
NR+F++++GVYDY VS EF+YM + GL P ++D+ L+ KL+G+GG+ IK+++VQ
Sbjct 3521 NRFFKVSVGVYDYTVSAAEFKYMVANGLRAPTGTLDSLLLSAKLIGIGGERNIKISSVQ 3579
>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781
Score = 96.7 bits (239), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 80/266 (30%), Positives = 135/266 (51%), Gaps = 17/266 (6%)
Query 30 QWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPAS 89
++ FF++ P + +S+ M +KHK F +FL+P+L + N+ +
Sbjct 3326 SYTKFFWVNPGYVTPMFACLSLLSSLLMFTLKHKTLFFQVFLIPALIVTSCINLAFD--- 3382
Query 90 WVMRIMTWL-DMVD--TSLSGFKLKDCVMYASAVVLLILMTART--VYDDGARRVWTLMN 144
+ + +L + D SL GF + V V+ IL T ++ A V ++
Sbjct 3383 --VEVYNYLAEHFDYHVSLMGFNAQGLVNIFVCFVVTILHGTYTWRFFNTPASSVTYVVA 3440
Query 145 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 204
+LT Y +Y A D L SVT N+ V V + + V+M + + P F
Sbjct 3441 LLTAAYNYFY--ASDILSCAMTLFASVTGNW--FVGAVCY--KVAVYMALRF-PTFVAIF 3493
Query 205 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 264
++ +M Y LGYF C++G+ NR+F++++GVYDY VS EF+YM + GL P
Sbjct 3494 GDIKSVMFCYLVLGYFTCCFYGILYWFNRFFKVSVGVYDYTVSAAEFKYMVANGLRAPTG 3553
Query 265 SIDAFKLNIKLLGVGGKPCIKVATVQ 290
++D+ L+ KL+G+GG+ IK+++VQ
Sbjct 3554 TLDSLLLSAKLIGIGGERNIKISSVQ 3579
>sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus
NL63 OX=277944 GN=1a PE=1 SV=1
Length=4060
Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 73/233 (31%), Positives = 121/233 (52%), Gaps = 8/233 (3%)
Query 58 MFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYA 117
MF+KHK FL +FLLP++ A +N V ++++ + + S+ ++ V
Sbjct 3297 MFLKHKFLFLQVFLLPTVIATALYNCVL--DYYIVKFLADHFNYNVSVLQMDVQGLVNVL 3354
Query 118 SAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSG 177
+ ++ L T R + + +++ + Y +Y + M+ IS + Y G
Sbjct 3355 VCLFVVFLHTWRFSKERFTHWFTYVCSLIAVAYTYFYSGDFLSLLVMFLCAIS-SDWYIG 3413
Query 178 VVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRL 237
+ V L+R IVF E +F + G+ ++ ++VY GY Y+G+ NR+F+
Sbjct 3414 AI--VFRLSRLIVFFSPE--SVFSVFGD-VKLTLVVYLICGYLVCTYWGILYWFNRFFKC 3468
Query 238 TLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
T+GVYD+ VS EF+YM + GL P DA L+ KLLG+GG CIK++TVQ
Sbjct 3469 TMGVYDFKVSAAEFKYMVANGLHAPHGPFDALWLSFKLLGIGGDRCIKISTVQ 3521
>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729
Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 73/233 (31%), Positives = 121/233 (52%), Gaps = 8/233 (3%)
Query 58 MFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYA 117
MF+KHK FL +FLLP++ A +N V ++++ + + S+ ++ V
Sbjct 3297 MFLKHKFLFLQVFLLPTVIATALYNCVL--DYYIVKFLADHFNYNVSVLQMDVQGLVNVL 3354
Query 118 SAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSG 177
+ ++ L T R + + +++ + Y +Y + M+ IS + Y G
Sbjct 3355 VCLFVVFLHTWRFSKERFTHWFTYVCSLIAVAYTYFYSGDFLSLLVMFLCAIS-SDWYIG 3413
Query 178 VVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRL 237
+ V L+R IVF E +F + G+ ++ ++VY GY Y+G+ NR+F+
Sbjct 3414 AI--VFRLSRLIVFFSPE--SVFSVFGD-VKLTLVVYLICGYLVCTYWGILYWFNRFFKC 3468
Query 238 TLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
T+GVYD+ VS EF+YM + GL P DA L+ KLLG+GG CIK++TVQ
Sbjct 3469 TMGVYDFKVSAAEFKYMVANGLHAPHGPFDALWLSFKLLGIGGDRCIKISTVQ 3521
>sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus
229E OX=11137 GN=1a PE=1 SV=1
Length=4085
Score = 90.5 bits (223), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 77/252 (31%), Positives = 127/252 (50%), Gaps = 18/252 (7%)
Query 44 PFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL-DMVD 102
PF + ++A+S VKHK FL +FLLPS+ A N +W + L + D
Sbjct 3308 PFMILLVALSLCLTFVVKHKVLFLQVFLLPSIIVAAIQN-----CAWDYHVTKVLAEKFD 3362
Query 103 TSLSGFKLKDCVMYASAVVLL---ILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALD 159
++S ++ D + + + L +L T R + L +++ ++Y Y
Sbjct 3363 YNVSVMQM-DIQGFVNIFICLFVALLHTWRFAKERCTHWCTYLFSLIAVLYTALYSY--- 3418
Query 160 QAISMWALIISVTSNYSGVVTTVMFLAR-GIVFMCVEYCPIFFITGNTLQCIMLVYCFLG 218
+S+ +++ SN + + + R G+ F+ VEY F + ++ ++L Y LG
Sbjct 3419 DYVSLLVMLLCAISNEWYIGAIIFRICRFGVAFLPVEYVSYF----DGVKTVLLFYMLLG 3474
Query 219 YFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGV 278
+ Y+GL +NR+ + TLGVYD+ VS EF+YM + GL P DA L+ KL+G+
Sbjct 3475 FVSCMYYGLLYWINRFCKCTLGVYDFCVSPAEFKYMVANGLNAPNGPFDALFLSFKLMGI 3534
Query 279 GGKPCIKVATVQ 290
GG IKV+TVQ
Sbjct 3535 GGPRTIKVSTVQ 3546
>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus
229E OX=11137 GN=rep PE=1 SV=1
Length=6758
Score = 90.1 bits (222), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 77/252 (31%), Positives = 127/252 (50%), Gaps = 18/252 (7%)
Query 44 PFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL-DMVD 102
PF + ++A+S VKHK FL +FLLPS+ A N +W + L + D
Sbjct 3308 PFMILLVALSLCLTFVVKHKVLFLQVFLLPSIIVAAIQN-----CAWDYHVTKVLAEKFD 3362
Query 103 TSLSGFKLKDCVMYASAVVLL---ILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALD 159
++S ++ D + + + L +L T R + L +++ ++Y Y
Sbjct 3363 YNVSVMQM-DIQGFVNIFICLFVALLHTWRFAKERCTHWCTYLFSLIAVLYTALYSY--- 3418
Query 160 QAISMWALIISVTSNYSGVVTTVMFLAR-GIVFMCVEYCPIFFITGNTLQCIMLVYCFLG 218
+S+ +++ SN + + + R G+ F+ VEY F + ++ ++L Y LG
Sbjct 3419 DYVSLLVMLLCAISNEWYIGAIIFRICRFGVAFLPVEYVSYF----DGVKTVLLFYMLLG 3474
Query 219 YFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGV 278
+ Y+GL +NR+ + TLGVYD+ VS EF+YM + GL P DA L+ KL+G+
Sbjct 3475 FVSCMYYGLLYWINRFCKCTLGVYDFCVSPAEFKYMVANGLNAPNGPFDALFLSFKLMGI 3534
Query 279 GGKPCIKVATVQ 290
GG IKV+TVQ
Sbjct 3535 GGPRTIKVSTVQ 3546
>sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=1a PE=1 SV=1
Length=4017
Score = 81.3 bits (199), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 52/130 (40%), Positives = 78/130 (60%), Gaps = 4/130 (3%)
Query 162 ISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYF 220
++M +I+S+T+ VV +A IV +CV P F++ ++CI +VY GY
Sbjct 3348 VNMLTMIVSLTTKDWMVVIASYRIAYYIV-VCV--MPSAFVSDFGFMKCISIVYMACGYL 3404
Query 221 CTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGG 280
CY+G+ +NR+ +T GVY + VS E +YM + L PKN+ DA L+ KL+GVGG
Sbjct 3405 FCCYYGILYWVNRFTCMTCGVYQFTVSAAELKYMTANNLSAPKNAYDAMILSAKLIGVGG 3464
Query 281 KPCIKVATVQ 290
K IK++TVQ
Sbjct 3465 KRNIKISTVQ 3474
>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=rep PE=1 SV=1
Length=6684
Score = 81.3 bits (199), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 52/130 (40%), Positives = 78/130 (60%), Gaps = 4/130 (3%)
Query 162 ISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYF 220
++M +I+S+T+ VV +A IV +CV P F++ ++CI +VY GY
Sbjct 3348 VNMLTMIVSLTTKDWMVVIASYRIAYYIV-VCV--MPSAFVSDFGFMKCISIVYMACGYL 3404
Query 221 CTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGG 280
CY+G+ +NR+ +T GVY + VS E +YM + L PKN+ DA L+ KL+GVGG
Sbjct 3405 FCCYYGILYWVNRFTCMTCGVYQFTVSAAELKYMTANNLSAPKNAYDAMILSAKLIGVGG 3464
Query 281 KPCIKVATVQ 290
K IK++TVQ
Sbjct 3465 KRNIKISTVQ 3474
>sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus
512/2005 OX=693999 GN=1a PE=3 SV=1
Length=4128
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 78/272 (29%), Positives = 135/272 (50%), Gaps = 19/272 (7%)
Query 23 LVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN 82
L L + S F++ P + II S+ M+ VKHK FL L+LLPSL V+ +N
Sbjct 3334 LFLSEMLNHSKLFWINPGYITPVFLAIIVASSALMLLVKHKLLFLQLYLLPSLCIVSGYN 3393
Query 83 MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWT- 141
++ + ++ D GF + + + ++ L T R + ++++
Sbjct 3394 -IFKDYHFYTYMLEEFDY-KVPFGGFNVTGVLNISLCCFVMGLHTFR--FLQTPNKIFSY 3449
Query 142 LMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCP--I 199
++ VLT++Y YY + + LI++ S + T F+ + P
Sbjct 3450 VVAVLTVLYTYYY------STDVLGLILTSMSGF----TNYWFIGTATYKLATYVLPHTS 3499
Query 200 FFITGNTLQCIMLVYCFLGYFCTC-YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQG 258
+ + ++ ++ +Y LGY C C Y+G +NR+ +LTLG Y++ VS EF+YM + G
Sbjct 3500 LLDSFDAIKAVVFLYLLLGY-CNCVYYGSLYWINRFCKLTLGCYEFKVSAAEFKYMVANG 3558
Query 259 LLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
L P DA L++KL+GVGG+ IK+++VQ
Sbjct 3559 LRAPTGVFDALILSLKLIGVGGRKTIKISSVQ 3590
>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793
Score = 80.1 bits (196), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 78/272 (29%), Positives = 135/272 (50%), Gaps = 19/272 (7%)
Query 23 LVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN 82
L L + S F++ P + II S+ M+ VKHK FL L+LLPSL V+ +N
Sbjct 3334 LFLSEMLNHSKLFWINPGYITPVFLAIIVASSALMLLVKHKLLFLQLYLLPSLCIVSGYN 3393
Query 83 MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWT- 141
++ + ++ D GF + + + ++ L T R + ++++
Sbjct 3394 -IFKDYHFYTYMLEEFDY-KVPFGGFNVTGVLNISLCCFVMGLHTFRFL--QTPNKIFSY 3449
Query 142 LMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCP--I 199
++ VLT++Y YY + + LI++ S + T F+ + P
Sbjct 3450 VVAVLTVLYTYYY------STDVLGLILTSMSGF----TNYWFIGTATYKLATYVLPHTS 3499
Query 200 FFITGNTLQCIMLVYCFLGYFCTC-YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQG 258
+ + ++ ++ +Y LGY C C Y+G +NR+ +LTLG Y++ VS EF+YM + G
Sbjct 3500 LLDSFDAIKAVVFLYLLLGY-CNCVYYGSLYWINRFCKLTLGCYEFKVSAAEFKYMVANG 3558
Query 259 LLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
L P DA L++KL+GVGG+ IK+++VQ
Sbjct 3559 LRAPTGVFDALILSLKLIGVGGRKTIKISSVQ 3590
>sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=1a PE=1 SV=1
Length=3953
Score = 74.7 bits (182), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 41/106 (39%), Positives = 60/106 (57%), Gaps = 6/106 (6%)
Query 189 IVFMCVE----YCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDY 244
IVF C + YC + L +M+ +G+ CTCYFGL+ +N+ F LTLG Y++
Sbjct 3278 IVFKCAKWMLYYCNATYFNNYVLMAVMVN--GIGWLCTCYFGLYWWVNKVFGLTLGKYNF 3335
Query 245 LVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
VS ++RYM + PPK + F NI + G+GG + +ATVQ
Sbjct 3336 KVSVDQYRYMCLHKVNPPKTVWEVFTTNILIQGIGGDRVLPIATVQ 3381
>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709
Score = 74.3 bits (181), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 64/241 (27%), Positives = 121/241 (50%), Gaps = 13/241 (5%)
Query 60 VKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
+KHK F F++PS+ N+V+ ++ + ++ V+T+ ++ ++
Sbjct 3262 IKHKMLFFMSFVMPSVILATAHNVVW-DMTYYESLQVLVENVNTTFLPVDMQGVMLALFC 3320
Query 120 VVLLILMTAR------TVYDDGARRVWTLMNVLTLVYKVYYGNALDQ----AISMWALII 169
VV+ ++ T R + + A ++ + N++ L+ + D ++M ++I
Sbjct 3321 VVVFVICTIRFFTCKQSWFSLFATTIFVMFNIVKLLGMIGEPWTDDHFLLCLVNMLTMLI 3380
Query 170 SVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFC 229
S+T+ VV +A IV ++ P F ++C+ ++Y GY CY+G+
Sbjct 3381 SLTTKDWFVVFASYKVAYYIVVYVMQ--PAFVQDFGFVKCVSIIYMACGYLFCCYYGILY 3438
Query 230 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATV 289
+NR+ +T GVY + VS E +YM + L PK + DA L+ KL+G+GG IK++TV
Sbjct 3439 WVNRFTCMTCGVYQFTVSPAELKYMTANNLSAPKTAYDAMILSFKLMGIGGGRNIKISTV 3498
Query 290 Q 290
Q
Sbjct 3499 Q 3499
>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631
Score = 73.9 bits (180), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 41/106 (39%), Positives = 60/106 (57%), Gaps = 6/106 (6%)
Query 189 IVFMCVE----YCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDY 244
IVF C + YC + L +M+ +G+ CTCYFGL+ +N+ F LTLG Y++
Sbjct 3278 IVFKCAKWMLYYCNATYFNNYVLMAVMVN--GIGWLCTCYFGLYWWVNKVFGLTLGKYNF 3335
Query 245 LVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
VS ++RYM + PPK + F NI + G+GG + +ATVQ
Sbjct 3336 KVSVDQYRYMCLHKVNPPKTVWEVFTTNILIQGIGGDRVLPIATVQ 3381
>sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=1a PE=3
SV=1
Length=3951
Score = 73.2 bits (178), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 84/279 (30%), Positives = 127/279 (46%), Gaps = 52/279 (19%)
Query 42 FLPFAMGIIAMSAFAMMF-VKHKHAFLCLFLLPSLATVAYFNMVYMP-------ASWVMR 93
F +A I+ M+ + F VKH A++ FLLP+L TV +P + V+
Sbjct 3123 FYVYAAVILLMAVLFISFTVKHVMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIF 3182
Query 94 IMTWLDMV--DTSL----------SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVW 140
+ W D V DT + + FK ++ C M + LL+L + ++
Sbjct 3183 LSQWYDPVVFDTMVPWMFLPLVLYTAFKCVQGCYMNSFNTSLLMLYQFVKL----GFVIY 3238
Query 141 TLMNVLTLVYKVYYGNALDQAISMWALI-----ISVTSNYSGVVTTVMFLARGIVFMCVE 195
T N LT + GN W L +V +N S +F VF C +
Sbjct 3239 TSSNTLTAYTE---GN--------WELFFELVHTTVLANVSSNSLIGLF-----VFKCAK 3282
Query 196 ----YCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEF 251
YC ++ L +M V C +G+ CTCYFGL+ +N+ F LTLG Y++ VS ++
Sbjct 3283 WMLYYCNATYLNNYVLMAVM-VNC-IGWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQY 3340
Query 252 RYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
RYM + PPK + F NI + G+GG + +ATVQ
Sbjct 3341 RYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLPIATVQ 3379
>sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=1a PE=1 SV=1
Length=3951
Score = 73.2 bits (178), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 84/279 (30%), Positives = 127/279 (46%), Gaps = 52/279 (19%)
Query 42 FLPFAMGIIAMSAFAMMF-VKHKHAFLCLFLLPSLATVAYFNMVYMP-------ASWVMR 93
F +A I+ M+ + F VKH A++ FLLP+L TV +P + V+
Sbjct 3123 FYVYAAVILLMAVLFISFTVKHVMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIF 3182
Query 94 IMTWLDMV--DTSL----------SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVW 140
+ W D V DT + + FK ++ C M + LL+L + ++
Sbjct 3183 LSQWYDPVVFDTMVPWMFLPLVLYTAFKCVQGCYMNSFNTSLLMLYQFVKL----GFVIY 3238
Query 141 TLMNVLTLVYKVYYGNALDQAISMWALI-----ISVTSNYSGVVTTVMFLARGIVFMCVE 195
T N LT + GN W L +V +N S +F VF C +
Sbjct 3239 TSSNTLTAYTE---GN--------WELFFELVHTTVLANVSSNSLIGLF-----VFKCAK 3282
Query 196 ----YCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEF 251
YC ++ L +M V C +G+ CTCYFGL+ +N+ F LTLG Y++ VS ++
Sbjct 3283 WMLYYCNATYLNNYVLMAVM-VNC-IGWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQY 3340
Query 252 RYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
RYM + PPK + F NI + G+GG + +ATVQ
Sbjct 3341 RYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLPIATVQ 3379
>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep
PE=3 SV=1
Length=6629
Score = 72.8 bits (177), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 84/279 (30%), Positives = 127/279 (46%), Gaps = 52/279 (19%)
Query 42 FLPFAMGIIAMSAFAMMF-VKHKHAFLCLFLLPSLATVAYFNMVYMP-------ASWVMR 93
F +A I+ M+ + F VKH A++ FLLP+L TV +P + V+
Sbjct 3123 FYVYAAVILLMAVLFISFTVKHVMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIF 3182
Query 94 IMTWLDMV--DTSL----------SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVW 140
+ W D V DT + + FK ++ C M + LL+L + ++
Sbjct 3183 LSQWYDPVVFDTMVPWMFLPLVLYTAFKCVQGCYMNSFNTSLLMLYQFVKL----GFVIY 3238
Query 141 TLMNVLTLVYKVYYGNALDQAISMWALI-----ISVTSNYSGVVTTVMFLARGIVFMCVE 195
T N LT + GN W L +V +N S +F VF C +
Sbjct 3239 TSSNTLTAYTE---GN--------WELFFELVHTTVLANVSSNSLIGLF-----VFKCAK 3282
Query 196 ----YCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEF 251
YC ++ L +M V C +G+ CTCYFGL+ +N+ F LTLG Y++ VS ++
Sbjct 3283 WMLYYCNATYLNNYVLMAVM-VNC-IGWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQY 3340
Query 252 RYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
RYM + PPK + F NI + G+GG + +ATVQ
Sbjct 3341 RYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLPIATVQ 3379
>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1
SV=1
Length=6629
Score = 72.8 bits (177), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 84/279 (30%), Positives = 127/279 (46%), Gaps = 52/279 (19%)
Query 42 FLPFAMGIIAMSAFAMMF-VKHKHAFLCLFLLPSLATVAYFNMVYMP-------ASWVMR 93
F +A I+ M+ + F VKH A++ FLLP+L TV +P + V+
Sbjct 3123 FYVYAAVILLMAVLFISFTVKHVMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIF 3182
Query 94 IMTWLDMV--DTSL----------SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVW 140
+ W D V DT + + FK ++ C M + LL+L + ++
Sbjct 3183 LSQWYDPVVFDTMVPWMFLPLVLYTAFKCVQGCYMNSFNTSLLMLYQFVKL----GFVIY 3238
Query 141 TLMNVLTLVYKVYYGNALDQAISMWALI-----ISVTSNYSGVVTTVMFLARGIVFMCVE 195
T N LT + GN W L +V +N S +F VF C +
Sbjct 3239 TSSNTLTAYTE---GN--------WELFFELVHTTVLANVSSNSLIGLF-----VFKCAK 3282
Query 196 ----YCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEF 251
YC ++ L +M V C +G+ CTCYFGL+ +N+ F LTLG Y++ VS ++
Sbjct 3283 WMLYYCNATYLNNYVLMAVM-VNC-IGWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQY 3340
Query 252 RYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
RYM + PPK + F NI + G+GG + +ATVQ
Sbjct 3341 RYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLPIATVQ 3379
>sp|Q9VHM2|VP35L_DROME VPS35 endosomal protein sorting factor-like
OS=Drosophila melanogaster OX=7227 GN=CG8202 PE=2 SV=3
Length=942
Score = 39.3 bits (90), Expect = 0.039, Method: Composition-based stats.
Identities = 28/97 (29%), Positives = 44/97 (45%), Gaps = 13/97 (13%)
Query 133 DDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLA------ 186
DD R++ L+NV ++KV++GN L+Q +S + SN V T++ A
Sbjct 609 DDERRQIAQLINVF--IHKVHFGNDLEQQLSFYVEARGTFSNLDAVYVTLVHAACKLATR 666
Query 187 -----RGIVFMCVEYCPIFFITGNTLQCIMLVYCFLG 218
G V C+ YC I + +Q M +Y G
Sbjct 667 NRSKSTGFVKACIAYCFITIPSIEAVQQQMNLYLLCG 703
>sp|Q9DCS1|T176A_MOUSE Transmembrane protein 176A OS=Mus musculus
OX=10090 GN=Tmem176a PE=1 SV=2
Length=244
Score = 33.1 bits (74), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 0/69 (0%)
Query 13 WLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLL 72
W++ T+L +L V++ T + + + PF GI+AM A A+ F+ K C L+
Sbjct 65 WVVQTVLGALSVVLGGTLYIGHYLAMYSEGAPFWTGIVAMLAGAVAFLHKKRGGTCWALM 124
Query 73 PSLATVAYF 81
+L +A F
Sbjct 125 RTLLVLASF 133
Lambda K H a alpha
0.333 0.142 0.456 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 24192043546
Results from round 2
Query= YP_009725302.1 nsp6 [Severe acute respiratory syndrome coronavirus
2]
Length=290
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus... 361 8e-113
sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus R... 360 1e-112
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res... 359 3e-112
sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respi... 359 5e-112
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus... 358 1e-111
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus... 357 2e-111
sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus 2... 357 2e-111
sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus H... 356 5e-111
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re... 352 2e-109
sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute resp... 350 4e-109
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir... 320 1e-98
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi... 319 3e-98
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi... 319 3e-98
sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus... 318 1e-97
sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronaviru... 317 1e-97
sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronaviru... 317 2e-97
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res... 310 4e-95
sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respi... 310 6e-95
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus... 309 9e-95
sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus H... 309 9e-95
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus... 308 1e-94
sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus 1... 308 3e-94
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi... 307 5e-94
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi... 307 6e-94
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir... 307 6e-94
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus... 306 8e-94
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir... 306 1e-93
sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus H... 305 2e-93
sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus... 305 2e-93
sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronaviru... 305 3e-93
sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronaviru... 305 3e-93
sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus... 303 1e-92
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir... 302 3e-92
sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus... 300 2e-91
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir... 298 5e-91
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir... 297 2e-90
sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus... 296 3e-90
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir... 296 3e-90
sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus... 293 3e-89
sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus... 293 4e-89
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus... 292 9e-89
sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus H... 289 8e-88
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir... 248 2e-73
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir... 247 5e-73
sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus... 245 2e-72
sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus... 245 2e-72
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi... 244 4e-72
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir... 244 5e-72
sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic ... 243 2e-71
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi... 224 3e-65
sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmiss... 224 4e-65
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus... 222 2e-64
sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus 5... 222 3e-64
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious... 184 4e-51
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou... 184 4e-51
sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious ... 182 2e-50
sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious b... 182 2e-50
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious... 179 1e-49
sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious b... 177 9e-49
Sequences not found previously or not previously below threshold:
sp|Q8I7T3|SADA_DICDI Substrate-adhesion molecule OS=Dictyostelium... 31.9 9.4
>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071
Score = 361 bits (927), Expect = 8e-113, Method: Composition-based stats.
Identities = 253/289 (88%), Positives = 275/289 (95%), Gaps = 0/289 (0%)
Query 2 AVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 61
KR +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VK
Sbjct 3546 KFKRIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAVAACAMLLVK 3605
Query 62 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 121
HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+V
Sbjct 3606 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALV 3665
Query 122 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 181
LL+LMTARTVYDD ARRVWTLMNV+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT
Sbjct 3666 LLVLMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTT 3725
Query 182 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 241
+MFLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGV
Sbjct 3726 IMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGV 3785
Query 242 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YDYLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3786 YDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3834
>sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus
Rp3/2004 OX=349344 GN=1a PE=3 SV=1
Length=4380
Score = 360 bits (925), Expect = 1e-112, Method: Composition-based stats.
Identities = 253/289 (88%), Positives = 275/289 (95%), Gaps = 0/289 (0%)
Query 2 AVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 61
KR +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VK
Sbjct 3546 KFKRIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAVAACAMLLVK 3605
Query 62 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 121
HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+V
Sbjct 3606 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALV 3665
Query 122 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 181
LL+LMTARTVYDD ARRVWTLMNV+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT
Sbjct 3666 LLVLMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTT 3725
Query 182 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 241
+MFLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGV
Sbjct 3726 IMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGV 3785
Query 242 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YDYLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3786 YDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3834
>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score = 359 bits (922), Expect = 3e-112, Method: Composition-based stats.
Identities = 253/289 (88%), Positives = 275/289 (95%), Gaps = 0/289 (0%)
Query 2 AVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 61
K+ +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VK
Sbjct 3548 KFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVK 3607
Query 62 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 121
HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+V
Sbjct 3608 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALV 3667
Query 122 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 181
LLILMTARTVYDD ARRVWTLMNV+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT
Sbjct 3668 LLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTT 3727
Query 182 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 241
+MFLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGV
Sbjct 3728 IMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGV 3787
Query 242 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YDYLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3788 YDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3836
>sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respiratory
syndrome coronavirus OX=694009 GN=1a PE=1 SV=1
Length=4382
Score = 359 bits (921), Expect = 5e-112, Method: Composition-based stats.
Identities = 253/289 (88%), Positives = 275/289 (95%), Gaps = 0/289 (0%)
Query 2 AVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 61
K+ +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VK
Sbjct 3548 KFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVK 3607
Query 62 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 121
HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+V
Sbjct 3608 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALV 3667
Query 122 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 181
LLILMTARTVYDD ARRVWTLMNV+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT
Sbjct 3668 LLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTT 3727
Query 182 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 241
+MFLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGV
Sbjct 3728 IMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGV 3787
Query 242 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YDYLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3788 YDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3836
>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079
Score = 358 bits (918), Expect = 1e-111, Method: Composition-based stats.
Identities = 251/289 (87%), Positives = 275/289 (95%), Gaps = 0/289 (0%)
Query 2 AVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 61
K+ +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VK
Sbjct 3554 KFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVK 3613
Query 62 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 121
HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+V
Sbjct 3614 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALV 3673
Query 122 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 181
LL+LMTARTVYDD ARRVWTLMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT
Sbjct 3674 LLVLMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTT 3733
Query 182 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 241
+MFLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGV
Sbjct 3734 IMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGV 3793
Query 242 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YDYLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3794 YDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3842
>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067
Score = 357 bits (916), Expect = 2e-111, Method: Composition-based stats.
Identities = 253/289 (88%), Positives = 276/289 (96%), Gaps = 0/289 (0%)
Query 2 AVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 61
K+ +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPFA+GI+A++A AM+ VK
Sbjct 3542 KFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFALGIMAVAACAMLLVK 3601
Query 62 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 121
HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+V
Sbjct 3602 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALV 3661
Query 122 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 181
LLILMTARTVYDD ARRVWTLMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT
Sbjct 3662 LLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTT 3721
Query 182 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 241
+MFLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGV
Sbjct 3722 IMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGV 3781
Query 242 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YDYLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3782 YDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3830
>sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus
279/2005 OX=389167 GN=1a PE=3 SV=1
Length=4388
Score = 357 bits (915), Expect = 2e-111, Method: Composition-based stats.
Identities = 251/289 (87%), Positives = 275/289 (95%), Gaps = 0/289 (0%)
Query 2 AVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 61
K+ +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VK
Sbjct 3554 KFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVK 3613
Query 62 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 121
HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+V
Sbjct 3614 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALV 3673
Query 122 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 181
LL+LMTARTVYDD ARRVWTLMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT
Sbjct 3674 LLVLMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTT 3733
Query 182 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 241
+MFLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGV
Sbjct 3734 IMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGV 3793
Query 242 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YDYLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3794 YDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3842
>sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus
HKU3 OX=442736 GN=1a PE=3 SV=1
Length=4376
Score = 356 bits (913), Expect = 5e-111, Method: Composition-based stats.
Identities = 253/289 (88%), Positives = 276/289 (96%), Gaps = 0/289 (0%)
Query 2 AVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 61
K+ +KGTHHW+LLT LTSLL+LVQSTQWSLFFF+YENAFLPFA+GI+A++A AM+ VK
Sbjct 3542 KFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFALGIMAVAACAMLLVK 3601
Query 62 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 121
HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+V
Sbjct 3602 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALV 3661
Query 122 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 181
LLILMTARTVYDD ARRVWTLMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT
Sbjct 3662 LLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTT 3721
Query 182 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 241
+MFLAR IVF+CVEY P+ FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGV
Sbjct 3722 IMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGV 3781
Query 242 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
YDYLVSTQEFRYMNSQGLLPPK+SIDAFKLNIKLLG+GGKPCIKVATVQ
Sbjct 3782 YDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3830
>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1
SV=1
Length=7096
Score = 352 bits (902), Expect = 2e-109, Method: Composition-based stats.
Identities = 290/290 (100%), Positives = 290/290 (100%), Gaps = 0/290 (0%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV
Sbjct 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV 120
KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV
Sbjct 3630 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV 3689
Query 121 VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT 180
VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT
Sbjct 3690 VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT 3749
Query 181 TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG 240
TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG
Sbjct 3750 TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG 3809
Query 241 VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ
Sbjct 3810 VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 3859
>sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 PE=1 SV=1
Length=4405
Score = 350 bits (899), Expect = 4e-109, Method: Composition-based stats.
Identities = 290/290 (100%), Positives = 290/290 (100%), Gaps = 0/290 (0%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV
Sbjct 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV 120
KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV
Sbjct 3630 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV 3689
Query 121 VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT 180
VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT
Sbjct 3690 VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT 3749
Query 181 TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG 240
TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG
Sbjct 3750 TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG 3809
Query 241 VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ
Sbjct 3810 VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 3859
>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124
Score = 320 bits (821), Expect = 1e-98, Method: Composition-based stats.
Identities = 87/291 (30%), Positives = 156/291 (54%), Gaps = 5/291 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KGT W+L + L ++ +W++F ++ L + + +FAM+ V
Sbjct 3583 SKRTRVVKGTCCWILASTLLFCSIISAFVKWTMFMYV-TTHMLGVTLCALCFVSFAMLLV 3641
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L +F++P L T+ Y N +V S+ WL ++ + + +
Sbjct 3642 KHKHLYLTMFIMPVLCTLFYTNYLVVYKQSFRGLAYAWLSHFVPAVDYTYMDEVLYGVVL 3701
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
+V ++ +T R++ D ++ + +++LV Y+G L++ + + S+ Y+
Sbjct 3702 LVAMVFVTMRSINHDVFSVMFLVGRLVSLVSMWYFGANLEEEV--LLFLTSLFGTYTWTT 3759
Query 180 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 239
+ A+ ++ + ++F ++ ++L Y +GY C CY+G+ LLN FR+ L
Sbjct 3760 MLSLATAK-VIAKWLAVNVLYFTDVPQVKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPL 3818
Query 240 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
GVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +Q
Sbjct 3819 GVYNYKISVQELRYMNANGLRPPRNSFEALVLNFKLLGIGGVPVIEVSQIQ 3869
>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180
Score = 319 bits (818), Expect = 3e-98, Method: Composition-based stats.
Identities = 84/292 (29%), Positives = 153/292 (52%), Gaps = 6/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R IKGT W+L + ++ +W++F ++ L + + FAM+ +
Sbjct 3640 SKRTRVIKGTCCWILASTFLFCSIISAFVKWTMFMYVT-THMLGVTLCALCFVIFAMLLI 3698
Query 61 KHKHAFLCLFLLPSLATVAYFNMVY--MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYAS 118
KHKH +L ++++P L T+ Y N + S+ WL ++ + + +
Sbjct 3699 KHKHLYLTMYIMPVLCTLFYTNYLVVGYKQSFRGLAYAWLSYFVPAVDYTYMDEVLYGVV 3758
Query 119 AVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+V ++ +T R++ D ++ + +++LV Y+G L++ + + S+ Y+
Sbjct 3759 LLVAMVFVTMRSINHDVFSTMFLVGRLVSLVSMWYFGANLEEEV--LLFLTSLFGTYTWT 3816
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
+ A+ ++ + ++F ++ ++L Y +GY C CY+G+ LLN FR+
Sbjct 3817 TMLSLATAK-VIAKWLAVNVLYFTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMP 3875
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +Q
Sbjct 3876 LGVYNYKISVQELRYMNANGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQ 3927
>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176
Score = 319 bits (817), Expect = 3e-98, Method: Composition-based stats.
Identities = 83/290 (29%), Positives = 152/290 (52%), Gaps = 4/290 (1%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R IKGT W+L + ++ +W++F ++ L + + +FAM+ +
Sbjct 3636 SKRTRVIKGTCCWILASTFLFCSIISAFVKWTMFMYVT-THMLGVTLCALCFVSFAMLLI 3694
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV 120
KHKH +L ++++P L T +V S+ WL ++ + + + +
Sbjct 3695 KHKHLYLTMYIMPVLCTFYTNYLVVYKQSFRGLAYAWLSHFVPAVDYTYMDEVLYGVVLL 3754
Query 121 VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT 180
V ++ +T R++ D ++ + +++LV Y+G L++ + + S+ Y+
Sbjct 3755 VAMVFVTMRSINHDVFSIMFLVGRLVSLVSMWYFGANLEEEV--LLFLTSLFGTYTWTTM 3812
Query 181 TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG 240
+ A+ ++ + ++F ++ ++L Y +GY C CY+G+ LLN FR+ LG
Sbjct 3813 LSLATAK-VIAKWLAVNVLYFTDVPQIKLVLLSYLCIGYVCCCYWGILSLLNSIFRMPLG 3871
Query 241 VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
VY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +Q
Sbjct 3872 VYNYKISVQELRYMNANGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQ 3921
>sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus
(strain 2) OX=76344 GN=1a PE=3 SV=1
Length=4416
Score = 318 bits (814), Expect = 1e-97, Method: Composition-based stats.
Identities = 87/291 (30%), Positives = 156/291 (54%), Gaps = 5/291 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KGT W+L + L ++ +W++F ++ L + + +FAM+ V
Sbjct 3583 SKRTRVVKGTCCWILASTLLFCSIISAFVKWTMFMYVT-THMLGVTLCALCFVSFAMLLV 3641
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L +F++P L T+ Y N +V S+ WL ++ + + +
Sbjct 3642 KHKHLYLTMFIMPVLCTLFYTNYLVVYKQSFRGLAYAWLSHFVPAVDYTYMDEVLYGVVL 3701
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
+V ++ +T R++ D ++ + +++LV Y+G L++ + + S+ Y+
Sbjct 3702 LVAMVFVTMRSINHDVFSVMFLVGRLVSLVSMWYFGANLEEEV--LLFLTSLFGTYTWTT 3759
Query 180 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 239
+ A+ ++ + ++F ++ ++L Y +GY C CY+G+ LLN FR+ L
Sbjct 3760 MLSLATAK-VIAKWLAVNVLYFTDVPQVKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPL 3818
Query 240 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
GVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +Q
Sbjct 3819 GVYNYKISVQELRYMNANGLRPPRNSFEALVLNFKLLGIGGVPVIEVSQIQ 3869
>sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronavirus
(strain A59) OX=11142 GN=1a PE=1 SV=1
Length=4468
Score = 317 bits (813), Expect = 1e-97, Method: Composition-based stats.
Identities = 83/290 (29%), Positives = 152/290 (52%), Gaps = 4/290 (1%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R IKGT W+L + ++ +W++F ++ L + + +FAM+ +
Sbjct 3636 SKRTRVIKGTCCWILASTFLFCSIISAFVKWTMFMYV-TTHMLGVTLCALCFVSFAMLLI 3694
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAV 120
KHKH +L ++++P L T +V S+ WL ++ + + + +
Sbjct 3695 KHKHLYLTMYIMPVLCTFYTNYLVVYKQSFRGLAYAWLSHFVPAVDYTYMDEVLYGVVLL 3754
Query 121 VLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVT 180
V ++ +T R++ D ++ + +++LV Y+G L++ + + S+ Y+
Sbjct 3755 VAMVFVTMRSINHDVFSIMFLVGRLVSLVSMWYFGANLEEEV--LLFLTSLFGTYTWTTM 3812
Query 181 TVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLG 240
+ A+ ++ + ++F ++ ++L Y +GY C CY+G+ LLN FR+ LG
Sbjct 3813 LSLATAK-VIAKWLAVNVLYFTDVPQIKLVLLSYLCIGYVCCCYWGILSLLNSIFRMPLG 3871
Query 241 VYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
VY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +Q
Sbjct 3872 VYNYKISVQELRYMNANGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQ 3921
>sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronavirus
(strain JHM) OX=11144 GN=1a PE=1 SV=1
Length=4474
Score = 317 bits (812), Expect = 2e-97, Method: Composition-based stats.
Identities = 84/292 (29%), Positives = 153/292 (52%), Gaps = 6/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R IKGT W+L + ++ +W++F ++ L + + FAM+ +
Sbjct 3640 SKRTRVIKGTCCWILASTFLFCSIISAFVKWTMFMYVT-THMLGVTLCALCFVIFAMLLI 3698
Query 61 KHKHAFLCLFLLPSLATVAYFNMVY--MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYAS 118
KHKH +L ++++P L T+ Y N + S+ WL ++ + + +
Sbjct 3699 KHKHLYLTMYIMPVLCTLFYTNYLVVGYKQSFRGLAYAWLSYFVPAVDYTYMDEVLYGVV 3758
Query 119 AVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+V ++ +T R++ D ++ + +++LV Y+G L++ + + S+ Y+
Sbjct 3759 LLVAMVFVTMRSINHDVFSTMFLVGRLVSLVSMWYFGANLEEEV--LLFLTSLFGTYTWT 3816
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
+ A+ ++ + ++F ++ ++L Y +GY C CY+G+ LLN FR+
Sbjct 3817 TMLSLATAK-VIAKWLAVNVLYFTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMP 3875
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +Q
Sbjct 3876 LGVYNYKISVQELRYMNANGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQ 3927
>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=rep PE=1 SV=1
Length=7078
Score = 310 bits (794), Expect = 4e-95, Method: Composition-based stats.
Identities = 101/294 (34%), Positives = 163/294 (55%), Gaps = 6/294 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S V++ GT HWL T++++ ++++Q+T+++L+ +L+E + AF M+ V
Sbjct 3554 SGVRKVTYGTAHWLFATLVSTYVIILQATKFTLWNYLFETIPTQLFPLLFVTMAFVMLLV 3613
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH FL LFLLP + Y N+VY P +S ++ + WL + + D +Y
Sbjct 3614 KHKHTFLTLFLLPVAICLTYANIVYEPTTPISSALIAVANWLAPTNAYMRTTH-TDIGVY 3672
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S ++L+++ R + L + + +Y G A I+ + ++TS+Y+
Sbjct 3673 ISMSLVLVIVVKRLYNPSLSNFALALCSGVMWLYTYSIGEA-SSPIAYLVFVTTLTSDYT 3731
Query 177 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 236
V + LA+ + Y P + ++ I+L+Y LG+ CTCYFG+F LLN R
Sbjct 3732 ITVFVTVNLAKVCTYAIFAYSPQLTLVFPEVKMILLLYTCLGFMCTCYFGVFSLLNLKLR 3791
Query 237 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+GVYD+ VSTQEFR+M + L P+NS +A LN KL+G+GG PCIKVA +Q
Sbjct 3792 APMGVYDFKVSTQEFRFMTANNLTAPRNSWEAMALNFKLIGIGGTPCIKVAAMQ 3845
>sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respiratory
syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=1a PE=1 SV=1
Length=4391
Score = 310 bits (793), Expect = 6e-95, Method: Composition-based stats.
Identities = 101/294 (34%), Positives = 163/294 (55%), Gaps = 6/294 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S V++ GT HWL T++++ ++++Q+T+++L+ +L+E + AF M+ V
Sbjct 3554 SGVRKVTYGTAHWLFATLVSTYVIILQATKFTLWNYLFETIPTQLFPLLFVTMAFVMLLV 3613
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH FL LFLLP + Y N+VY P +S ++ + WL + + D +Y
Sbjct 3614 KHKHTFLTLFLLPVAICLTYANIVYEPTTPISSALIAVANWLAPTNAYMRTTH-TDIGVY 3672
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S ++L+++ R + L + + +Y G A I+ + ++TS+Y+
Sbjct 3673 ISMSLVLVIVVKRLYNPSLSNFALALCSGVMWLYTYSIGEA-SSPIAYLVFVTTLTSDYT 3731
Query 177 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 236
V + LA+ + Y P + ++ I+L+Y LG+ CTCYFG+F LLN R
Sbjct 3732 ITVFVTVNLAKVCTYAIFAYSPQLTLVFPEVKMILLLYTCLGFMCTCYFGVFSLLNLKLR 3791
Query 237 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+GVYD+ VSTQEFR+M + L P+NS +A LN KL+G+GG PCIKVA +Q
Sbjct 3792 APMGVYDFKVSTQEFRFMTANNLTAPRNSWEAMALNFKLIGIGGTPCIKVAAMQ 3845
>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182
Score = 309 bits (792), Expect = 9e-95, Method: Composition-based stats.
Identities = 101/294 (34%), Positives = 161/294 (55%), Gaps = 6/294 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S VKR G HWL T+L + + +Q T+++++ +L+E L ++ + A M+ V
Sbjct 3645 SGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLTPLVLCVMACVMLTV 3704
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH FL LFLLP+ + Y N+VY P +S ++ + WL+ + D +Y
Sbjct 3705 KHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPASVYMRTTH-TDLGVY 3763
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S L ++ R + + L + + Y G+ ++ + ++TS+Y+
Sbjct 3764 LSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPLTYLMFLTTLTSDYT 3822
Query 177 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 236
V + +A+ + Y P ++ ++L+Y +GYFCT YFG+F LLN R
Sbjct 3823 VTVFLAVNVAKFFARVVFLYAPHAGFIFPEVKLVLLMYLAVGYFCTVYFGVFSLLNLKLR 3882
Query 237 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+ LGVYDY VSTQEFRY+ GL P+NS +A +LN+KL+G+GG PCIK+A+VQ
Sbjct 3883 VPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTPCIKIASVQ 3936
>sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus
HKU5 OX=694008 GN=1a PE=3 SV=1
Length=4481
Score = 309 bits (792), Expect = 9e-95, Method: Composition-based stats.
Identities = 101/294 (34%), Positives = 161/294 (55%), Gaps = 6/294 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S VKR G HWL T+L + + +Q T+++++ +L+E L ++ + A M+ V
Sbjct 3645 SGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLTPLVLCVMACVMLTV 3704
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH FL LFLLP+ + Y N+VY P +S ++ + WL+ + D +Y
Sbjct 3705 KHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPASVYMRTTH-TDLGVY 3763
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S L ++ R + + L + + Y G+ ++ + ++TS+Y+
Sbjct 3764 LSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPLTYLMFLTTLTSDYT 3822
Query 177 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 236
V + +A+ + Y P ++ ++L+Y +GYFCT YFG+F LLN R
Sbjct 3823 VTVFLAVNVAKFFARVVFLYAPHAGFIFPEVKLVLLMYLAVGYFCTVYFGVFSLLNLKLR 3882
Query 237 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+ LGVYDY VSTQEFRY+ GL P+NS +A +LN+KL+G+GG PCIK+A+VQ
Sbjct 3883 VPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTPCIKIASVQ 3936
>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126
Score = 308 bits (790), Expect = 1e-94, Method: Composition-based stats.
Identities = 106/294 (36%), Positives = 156/294 (53%), Gaps = 6/294 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S VKR G HWL+ T++ + + ++Q T+++++ +L+E + A M V
Sbjct 3605 SGVKRISYGFMHWLMSTLVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLFGFMACVMFTV 3664
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH FL LFLLP + Y N+VY P +S ++ + WL + L D +Y
Sbjct 3665 KHKHTFLSLFLLPVALCLTYANIVYEPQTLVSSTLIAVANWLTPTSVYMRTTHL-DFGLY 3723
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S +L ++ R + L + + Y G+ I+ I ++TS+Y+
Sbjct 3724 ISLSFVLAIIVRRLYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYT 3782
Query 177 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 236
V + LA+ I + Y P ++ ++L+Y LGY CT YFG+F LLN R
Sbjct 3783 ITVFATVNLAKFISGLVFLYAPHLGFILPEVKLVLLIYLCLGYMCTMYFGVFSLLNLKLR 3842
Query 237 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+ LGVYDY VSTQEFR++ GL P+NS +A LN KLLG+GG PCIKVATVQ
Sbjct 3843 VPLGVYDYSVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQ 3896
>sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus
133/2005 OX=389230 GN=1a PE=3 SV=1
Length=4441
Score = 308 bits (788), Expect = 3e-94, Method: Composition-based stats.
Identities = 106/294 (36%), Positives = 156/294 (53%), Gaps = 6/294 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S VKR G HWL+ T++ + + ++Q T+++++ +L+E + A M V
Sbjct 3605 SGVKRISYGFMHWLMSTLVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLFGFMACVMFTV 3664
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH FL LFLLP + Y N+VY P +S ++ + WL + L D +Y
Sbjct 3665 KHKHTFLSLFLLPVALCLTYANIVYEPQTLVSSTLIAVANWLTPTSVYMRTTHL-DFGLY 3723
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S +L ++ R + L + + Y G+ I+ I ++TS+Y+
Sbjct 3724 ISLSFVLAIIVRRLYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYT 3782
Query 177 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 236
V + LA+ I + Y P ++ ++L+Y LGY CT YFG+F LLN R
Sbjct 3783 ITVFATVNLAKFISGLVFLYAPHLGFILPEVKLVLLIYLCLGYMCTMYFGVFSLLNLKLR 3842
Query 237 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+ LGVYDY VSTQEFR++ GL P+NS +A LN KLLG+GG PCIKVATVQ
Sbjct 3843 VPLGVYDYSVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQ 3896
>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094
Score = 307 bits (786), Expect = 5e-94, Method: Composition-based stats.
Identities = 89/292 (30%), Positives = 159/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + AM+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + V+++V Y G+ L++ I ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEI--LLMLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094
Score = 307 bits (786), Expect = 6e-94, Method: Composition-based stats.
Identities = 89/292 (30%), Positives = 159/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + AM+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + V+++V Y G+ L++ I ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEI--LLMLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059
Score = 307 bits (786), Expect = 6e-94, Method: Composition-based stats.
Identities = 89/292 (30%), Positives = 159/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + AM+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + V+++V Y G+ L++ I ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEI--LLMLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119
Score = 306 bits (785), Expect = 8e-94, Method: Composition-based stats.
Identities = 104/294 (35%), Positives = 155/294 (53%), Gaps = 6/294 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S VKR G HWL+ T + + + ++Q T+++++ +L+E ++ A M V
Sbjct 3598 SGVKRISYGFIHWLISTFVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLLGFMACVMFTV 3657
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH F+ LFLLP + Y N+VY P +S ++ + WL + D +Y
Sbjct 3658 KHKHTFMSLFLLPVALCLTYANIVYEPQTLISSTLIAVANWLTPTSVYMRTTHF-DFGLY 3716
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S +L ++ R + L + + Y G+ I+ I ++TS+Y+
Sbjct 3717 ISLSFVLAIIVRRLYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYT 3775
Query 177 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 236
V + LA+ I + Y P ++ ++L+Y LGY CT YFG+F LLN R
Sbjct 3776 ITVFATVNLAKFISGLVFFYAPHLGFILPEVKLVLLIYLGLGYMCTMYFGVFSLLNLKLR 3835
Query 237 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+ LGVYDY VSTQEFR++ GL P+NS +A LN KLLG+GG PCIKVATVQ
Sbjct 3836 VPLGVYDYSVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQ 3889
>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095
Score = 306 bits (783), Expect = 1e-93, Method: Composition-based stats.
Identities = 89/292 (30%), Positives = 158/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R KGT W++ + ++ +W++F ++ N F + + + AM+ V
Sbjct 3550 SKRTRLFKGTVCWIMASTFLFSCIITAFVKWTMFMYVTTNMF-SITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L +++ P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYITPVLFTLLYNNYLVVYKHTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + ++++ Y G+ L++ I ++ S+ Y+
Sbjct 3668 LLVGMVFVTLRSINHDLFSFIMFVGRLISVFSLWYKGSNLEEEI--LLMLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M +A+ ++ V ++F ++ ++L Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TVLSMAVAK-VIAKWVAVNVLYFTDIPQIKIVLLCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus
HKU4 OX=694007 GN=1a PE=1 SV=1
Length=4434
Score = 305 bits (782), Expect = 2e-93, Method: Composition-based stats.
Identities = 104/294 (35%), Positives = 155/294 (53%), Gaps = 6/294 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S VKR G HWL+ T + + + ++Q T+++++ +L+E ++ A M V
Sbjct 3598 SGVKRISYGFIHWLISTFVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLLGFMACVMFTV 3657
Query 61 KHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMY 116
KHKH F+ LFLLP + Y N+VY P +S ++ + WL + D +Y
Sbjct 3658 KHKHTFMSLFLLPVALCLTYANIVYEPQTLISSTLIAVANWLTPTSVYMRTTHF-DFGLY 3716
Query 117 ASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYS 176
S +L ++ R + L + + Y G+ I+ I ++TS+Y+
Sbjct 3717 ISLSFVLAIIVRRLYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYT 3775
Query 177 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 236
V + LA+ I + Y P ++ ++L+Y LGY CT YFG+F LLN R
Sbjct 3776 ITVFATVNLAKFISGLVFFYAPHLGFILPEVKLVLLIYLGLGYMCTMYFGVFSLLNLKLR 3835
Query 237 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+ LGVYDY VSTQEFR++ GL P+NS +A LN KLLG+GG PCIKVATVQ
Sbjct 3836 VPLGVYDYSVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQ 3889
>sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=1a PE=3 SV=1
Length=4383
Score = 305 bits (782), Expect = 2e-93, Method: Composition-based stats.
Identities = 89/292 (30%), Positives = 159/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + AM+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + V+++V Y G+ L++ I ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEI--LLMLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=1a PE=3 SV=1
Length=4383
Score = 305 bits (781), Expect = 3e-93, Method: Composition-based stats.
Identities = 89/292 (30%), Positives = 159/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + AM+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + V+++V Y G+ L++ I ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEI--LLMLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=1a PE=3 SV=1
Length=4383
Score = 305 bits (780), Expect = 3e-93, Method: Composition-based stats.
Identities = 89/292 (30%), Positives = 159/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + AM+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + V+++V Y G+ L++ I ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEI--LLMLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus
OC43 OX=31631 GN=1a PE=1 SV=1
Length=4383
Score = 303 bits (776), Expect = 1e-92, Method: Composition-based stats.
Identities = 89/292 (30%), Positives = 158/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R KGT W++ + ++ +W++F ++ N F + + + AM+ V
Sbjct 3550 SKRTRLFKGTVCWIMASTFLFSCIITAFVKWTMFMYVTTNMF-SITFCALCVISLAMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L +++ P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYITPVLFTLLYNNYLVVYKHTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ D + + ++++ Y G+ L++ I ++ S+ Y+
Sbjct 3668 LLVGMVFVTLRSINHDLFSFIMFVGRLISVFSLWYKGSNLEEEI--LLMLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M +A+ ++ V ++F ++ ++L Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TVLSMAVAK-VIAKWVAVNVLYFTDIPQIKIVLLCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094
Score = 302 bits (773), Expect = 3e-92, Method: Composition-based stats.
Identities = 87/292 (30%), Positives = 157/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + M+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLTMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ + + V+++V Y G+ L++ I ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINQYLFSFIMFVGRVISVVSLWYMGSNLEEEI--LLMLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=1a PE=3 SV=1
Length=4383
Score = 300 bits (768), Expect = 2e-91, Method: Composition-based stats.
Identities = 87/292 (30%), Positives = 157/292 (54%), Gaps = 7/292 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S R +KG W++ + ++ +W++F ++ N L + + + M+ V
Sbjct 3550 SKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLTMLLV 3608
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3609 KHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGML 3667
Query 120 VVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 178
+++ ++ +T R++ + + V+++V Y G+ L++ I ++ S+ Y+
Sbjct 3668 LLIGMVFVTLRSINQYLFSFIMFVGRVISVVSLWYMGSNLEEEI--LLMLASLFGTYTWT 3725
Query 179 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 238
M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N FR+
Sbjct 3726 TALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMP 3784
Query 239 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ Q
Sbjct 3785 LGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQ 3836
>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182
Score = 298 bits (764), Expect = 5e-91, Method: Composition-based stats.
Identities = 86/291 (30%), Positives = 155/291 (53%), Gaps = 5/291 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3638 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYIN-THMIGVTLCVLCFVSFMMLLV 3696
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3697 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSYFVPAVNFTYVYEVFYGCIL 3756
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
V I +T ++ D ++ + ++TL+ Y+G+ L++ + I + Y+
Sbjct 3757 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDV--LLFITAFLGTYTWTT 3814
Query 180 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 239
+ +A+ IV + +F ++ I+L Y F+GY +CY+G F LLN FR+ +
Sbjct 3815 ILSLAIAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPM 3873
Query 240 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +Q
Sbjct 3874 GVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQ 3924
>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132
Score = 297 bits (760), Expect = 2e-90, Method: Composition-based stats.
Identities = 86/291 (30%), Positives = 155/291 (53%), Gaps = 5/291 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3588 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYIN-THMIGVTLCVLCFVSFMMLLV 3646
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3647 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYEVFYGCIL 3706
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
V I +T ++ D ++ + ++TL+ Y+G+ L++ + I + Y+
Sbjct 3707 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDV--LLFITAFLGTYTWTT 3764
Query 180 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 239
+ +A+ IV + +F ++ I+L Y F+GY +CY+G F LLN FR+ +
Sbjct 3765 ILSLAIAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPM 3823
Query 240 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +Q
Sbjct 3824 GVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQ 3874
>sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=1a PE=1 SV=1
Length=4471
Score = 296 bits (758), Expect = 3e-90, Method: Composition-based stats.
Identities = 86/291 (30%), Positives = 155/291 (53%), Gaps = 5/291 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3638 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYIN-THMIGVTLCVLCFVSFMMLLV 3696
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3697 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSYFVPAVNFTYVYEVFYGCIL 3756
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
V I +T ++ D ++ + ++TL+ Y+G+ L++ + I + Y+
Sbjct 3757 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDV--LLFITAFLGTYTWTT 3814
Query 180 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 239
+ +A+ IV + +F ++ I+L Y F+GY +CY+G F LLN FR+ +
Sbjct 3815 ILSLAIAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPM 3873
Query 240 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +Q
Sbjct 3874 GVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQ 3924
>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152
Score = 296 bits (758), Expect = 3e-90, Method: Composition-based stats.
Identities = 86/291 (30%), Positives = 155/291 (53%), Gaps = 5/291 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3608 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYIN-THMIGVTLCVLCFVSFMMLLV 3666
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3667 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGLTYVWLSYFVPAVNFTYVYEVFYGCIL 3726
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
V I +T ++ D ++ + ++TL+ Y+G+ L++ + I + Y+
Sbjct 3727 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDV--LLFITAFLGTYTWTT 3784
Query 180 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 239
+ +A+ IV + +F ++ I+L Y F+GY +CY+G F LLN FR+ +
Sbjct 3785 ILSLAIAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPM 3843
Query 240 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +Q
Sbjct 3844 GVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQ 3894
>sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=1a PE=3 SV=1
Length=4421
Score = 293 bits (751), Expect = 3e-89, Method: Composition-based stats.
Identities = 86/291 (30%), Positives = 155/291 (53%), Gaps = 5/291 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3588 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYIN-THMIGVTLCVLCFVSFMMLLV 3646
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3647 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYEVFYGCIL 3706
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
V I +T ++ D ++ + ++TL+ Y+G+ L++ + I + Y+
Sbjct 3707 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDV--LLFITAFLGTYTWTT 3764
Query 180 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 239
+ +A+ IV + +F ++ I+L Y F+GY +CY+G F LLN FR+ +
Sbjct 3765 ILSLAIAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPM 3823
Query 240 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +Q
Sbjct 3824 GVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQ 3874
>sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=1a PE=3 SV=1
Length=4441
Score = 293 bits (750), Expect = 4e-89, Method: Composition-based stats.
Identities = 86/291 (30%), Positives = 155/291 (53%), Gaps = 5/291 (2%)
Query 1 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 60
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3608 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYIN-THMIGVTLCVLCFVSFMMLLV 3666
Query 61 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 119
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3667 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGLTYVWLSYFVPAVNFTYVYEVFYGCIL 3726
Query 120 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 179
V I +T ++ D ++ + ++TL+ Y+G+ L++ + I + Y+
Sbjct 3727 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDV--LLFITAFLGTYTWTT 3784
Query 180 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 239
+ +A+ IV + +F ++ I+L Y F+GY +CY+G F LLN FR+ +
Sbjct 3785 ILSLAIAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPM 3843
Query 240 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +Q
Sbjct 3844 GVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQ 3894
>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930
Score = 292 bits (747), Expect = 9e-89, Method: Composition-based stats.
Identities = 98/289 (34%), Positives = 153/289 (53%), Gaps = 0/289 (0%)
Query 2 AVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 61
+ + T W + + ++L+L+Q QW+ L LP + F + +K
Sbjct 3411 KFQSMFRWTLQWFAIIFVLTILILLQLAQWTFVGALPFTLLLPLIGFVAVCVGFVSLLIK 3470
Query 62 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 121
HKH +L ++LLP AY+N Y P +++ + V+ D + V
Sbjct 3471 HKHTYLTVYLLPVAMVTAYYNFQYTPEGVQGYLLSLYNYVNPGRIDVIGTDLLTMLIISV 3530
Query 122 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 181
L++ R V D R+W + + +Y + G+A AIS ++SV +NY+GV
Sbjct 3531 ACTLLSVRMVRTDAYSRIWYVCTAVGWLYNCWTGSADTVAISYLTFMVSVFTNYTGVACA 3590
Query 182 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 241
++ A+ +V++ P + +C+++ Y +GY CTCYFG+F L+NR FR TLG
Sbjct 3591 SLYAAQFMVWVLKFLDPTILLLYGRFRCVLVCYLLVGYLCTCYFGVFNLINRLFRCTLGN 3650
Query 242 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
Y+Y+VS+QE RYMNS GLLPP NS A LNIKL G+GG P +V+T+Q
Sbjct 3651 YEYVVSSQELRYMNSHGLLPPTNSWQALMLNIKLAGIGGIPIYRVSTIQ 3699
>sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus
HKU9 OX=694006 GN=1a PE=3 SV=1
Length=4248
Score = 289 bits (740), Expect = 8e-88, Method: Composition-based stats.
Identities = 98/289 (34%), Positives = 153/289 (53%), Gaps = 0/289 (0%)
Query 2 AVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 61
+ + T W + + ++L+L+Q QW+ L LP + F + +K
Sbjct 3411 KFQSMFRWTLQWFAIIFVLTILILLQLAQWTFVGALPFTLLLPLIGFVAVCVGFVSLLIK 3470
Query 62 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 121
HKH +L ++LLP AY+N Y P +++ + V+ D + V
Sbjct 3471 HKHTYLTVYLLPVAMVTAYYNFQYTPEGVQGYLLSLYNYVNPGRIDVIGTDLLTMLIISV 3530
Query 122 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 181
L++ R V D R+W + + +Y + G+A AIS ++SV +NY+GV
Sbjct 3531 ACTLLSVRMVRTDAYSRIWYVCTAVGWLYNCWTGSADTVAISYLTFMVSVFTNYTGVACA 3590
Query 182 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 241
++ A+ +V++ P + +C+++ Y +GY CTCYFG+F L+NR FR TLG
Sbjct 3591 SLYAAQFMVWVLKFLDPTILLLYGRFRCVLVCYLLVGYLCTCYFGVFNLINRLFRCTLGN 3650
Query 242 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
Y+Y+VS+QE RYMNS GLLPP NS A LNIKL G+GG P +V+T+Q
Sbjct 3651 YEYVVSSQELRYMNSHGLLPPTNSWQALMLNIKLAGIGGIPIYRVSTIQ 3699
>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729
Score = 248 bits (632), Expect = 2e-73, Method: Composition-based stats.
Identities = 72/277 (26%), Positives = 130/277 (47%), Gaps = 8/277 (3%)
Query 14 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLP 73
+ L + + + ++ ++ P ++ +S MF+KHK FL +FLLP
Sbjct 3253 MFLFSVFFTMFWAELFIYTNTIWINPVILTPIFCLLLFLSLVLTMFLKHKFLFLQVFLLP 3312
Query 74 SLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYD 133
++ A +N V ++++ + + S+ ++ V + ++ L T R +
Sbjct 3313 TVIATALYNCVLD--YYIVKFLADHFNYNVSVLQMDVQGLVNVLVCLFVVFLHTWRFSKE 3370
Query 134 DGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMC 193
+ +++ + Y +Y +S+ + + S+ + V L+R IVF
Sbjct 3371 RFTHWFTYVCSLIAVAYTYFYSGDF---LSLLVMFLCAISSDWYIGAIVFRLSRLIVFFS 3427
Query 194 VEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRY 253
E F ++ ++VY GY Y+G+ NR+F+ T+GVYD+ VS EF+Y
Sbjct 3428 PE---SVFSVFGDVKLTLVVYLICGYLVCTYWGILYWFNRFFKCTMGVYDFKVSAAEFKY 3484
Query 254 MNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
M + GL P DA L+ KLLG+GG CIK++TVQ
Sbjct 3485 MVANGLHAPHGPFDALWLSFKLLGIGGDRCIKISTVQ 3521
>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus
229E OX=11137 GN=rep PE=1 SV=1
Length=6758
Score = 247 bits (630), Expect = 5e-73, Method: Composition-based stats.
Identities = 74/271 (27%), Positives = 131/271 (48%), Gaps = 10/271 (4%)
Query 21 SLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAY 80
++ + ++ ++ PF + ++A+S VKHK FL +FLLPS+ A
Sbjct 3285 FVMFWAELFVYTTTIWVNPGFLTPFMILLVALSLCLTFVVKHKVLFLQVFLLPSIIVAAI 3344
Query 81 FNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVW 140
N + V +++ + S+ ++ V + + +L T R +
Sbjct 3345 QNCAWD--YHVTKVLAEKFDYNVSVMQMDIQGFVNIFICLFVALLHTWRFAKERCTHWCT 3402
Query 141 TLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLAR-GIVFMCVEYCPI 199
L +++ ++Y Y +S+ +++ SN + + + R G+ F+ VEY
Sbjct 3403 YLFSLIAVLYTALYSY---DYVSLLVMLLCAISNEWYIGAIIFRICRFGVAFLPVEYVSY 3459
Query 200 FFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGL 259
F + ++ ++L Y LG+ Y+GL +NR+ + TLGVYD+ VS EF+YM + GL
Sbjct 3460 F----DGVKTVLLFYMLLGFVSCMYYGLLYWINRFCKCTLGVYDFCVSPAEFKYMVANGL 3515
Query 260 LPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
P DA L+ KL+G+GG IKV+TVQ
Sbjct 3516 NAPNGPFDALFLSFKLMGIGGPRTIKVSTVQ 3546
>sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus
229E OX=11137 GN=1a PE=1 SV=1
Length=4085
Score = 245 bits (626), Expect = 2e-72, Method: Composition-based stats.
Identities = 74/271 (27%), Positives = 131/271 (48%), Gaps = 10/271 (4%)
Query 21 SLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAY 80
++ + ++ ++ PF + ++A+S VKHK FL +FLLPS+ A
Sbjct 3285 FVMFWAELFVYTTTIWVNPGFLTPFMILLVALSLCLTFVVKHKVLFLQVFLLPSIIVAAI 3344
Query 81 FNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVW 140
N + V +++ + S+ ++ V + + +L T R +
Sbjct 3345 QNCAWD--YHVTKVLAEKFDYNVSVMQMDIQGFVNIFICLFVALLHTWRFAKERCTHWCT 3402
Query 141 TLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLAR-GIVFMCVEYCPI 199
L +++ ++Y Y +S+ +++ SN + + + R G+ F+ VEY
Sbjct 3403 YLFSLIAVLYTALYSY---DYVSLLVMLLCAISNEWYIGAIIFRICRFGVAFLPVEYVSY 3459
Query 200 FFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGL 259
F + ++ ++L Y LG+ Y+GL +NR+ + TLGVYD+ VS EF+YM + GL
Sbjct 3460 F----DGVKTVLLFYMLLGFVSCMYYGLLYWINRFCKCTLGVYDFCVSPAEFKYMVANGL 3515
Query 260 LPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
P DA L+ KL+G+GG IKV+TVQ
Sbjct 3516 NAPNGPFDALFLSFKLMGIGGPRTIKVSTVQ 3546
>sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus
NL63 OX=277944 GN=1a PE=1 SV=1
Length=4060
Score = 245 bits (625), Expect = 2e-72, Method: Composition-based stats.
Identities = 72/277 (26%), Positives = 130/277 (47%), Gaps = 8/277 (3%)
Query 14 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLP 73
+ L + + + ++ ++ P ++ +S MF+KHK FL +FLLP
Sbjct 3253 MFLFSVFFTMFWAELFIYTNTIWINPVILTPIFCLLLFLSLVLTMFLKHKFLFLQVFLLP 3312
Query 74 SLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYD 133
++ A +N V ++++ + + S+ ++ V + ++ L T R +
Sbjct 3313 TVIATALYNCVLD--YYIVKFLADHFNYNVSVLQMDVQGLVNVLVCLFVVFLHTWRFSKE 3370
Query 134 DGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMC 193
+ +++ + Y +Y +S+ + + S+ + V L+R IVF
Sbjct 3371 RFTHWFTYVCSLIAVAYTYFYSGDF---LSLLVMFLCAISSDWYIGAIVFRLSRLIVFFS 3427
Query 194 VEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRY 253
E F ++ ++VY GY Y+G+ NR+F+ T+GVYD+ VS EF+Y
Sbjct 3428 PE---SVFSVFGDVKLTLVVYLICGYLVCTYWGILYWFNRFFKCTMGVYDFKVSAAEFKY 3484
Query 254 MNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
M + GL P DA L+ KLLG+GG CIK++TVQ
Sbjct 3485 MVANGLHAPHGPFDALWLSFKLLGIGGDRCIKISTVQ 3521
>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781
Score = 244 bits (623), Expect = 4e-72, Method: Composition-based stats.
Identities = 80/279 (29%), Positives = 135/279 (48%), Gaps = 12/279 (4%)
Query 14 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLP 73
LL+ + + ++ FF++ P + +S+ M +KHK F +FL+P
Sbjct 3311 LLVGSFLTF-FWSELVSYTKFFWVNPGYVTPMFACLSLLSSLLMFTLKHKTLFFQVFLIP 3369
Query 74 SLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTV-- 131
+L + N+ + + + SL GF + V V+ IL T
Sbjct 3370 ALIVTSCINLAFDVEVYNY--LAEHFDYHVSLMGFNAQGLVNIFVCFVVTILHGTYTWRF 3427
Query 132 YDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVF 191
++ A V ++ +LT Y +Y A D L SVT N V V + + V+
Sbjct 3428 FNTPASSVTYVVALLTAAYNYFY--ASDILSCAMTLFASVTGN--WFVGAVCY--KVAVY 3481
Query 192 MCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEF 251
M + + P F ++ +M Y LGYF C++G+ NR+F++++GVYDY VS EF
Sbjct 3482 MALRF-PTFVAIFGDIKSVMFCYLVLGYFTCCFYGILYWFNRFFKVSVGVYDYTVSAAEF 3540
Query 252 RYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+YM + GL P ++D+ L+ KL+G+GG+ IK+++VQ
Sbjct 3541 KYMVANGLRAPTGTLDSLLLSAKLIGIGGERNIKISSVQ 3579
>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709
Score = 244 bits (623), Expect = 5e-72, Method: Composition-based stats.
Identities = 68/294 (23%), Positives = 137/294 (47%), Gaps = 13/294 (4%)
Query 7 IKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAF 66
+K + ++ I ++ ++ F ++ +S + +KHK F
Sbjct 3209 VKSIFYPMMTAIAILFAFWLEFFMYTPFTWINPTFVSVVLAITTLVSVLLVAGIKHKMLF 3268
Query 67 LCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILM 126
F++PS+ N+V+ ++ + ++ V+T+ ++ ++ VV+ ++
Sbjct 3269 FMSFVMPSVILATAHNVVW-DMTYYESLQVLVENVNTTFLPVDMQGVMLALFCVVVFVIC 3327
Query 127 TAR------TVYDDGARRVWTLMNVLTLVYKVYYGNALDQ----AISMWALIISVTSNYS 176
T R + + A ++ + N++ L+ + D ++M ++IS+T+
Sbjct 3328 TIRFFTCKQSWFSLFATTIFVMFNIVKLLGMIGEPWTDDHFLLCLVNMLTMLISLTTKDW 3387
Query 177 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 236
VV +A IV ++ P F ++C+ ++Y GY CY+G+ +NR+
Sbjct 3388 FVVFASYKVAYYIVVYVMQ--PAFVQDFGFVKCVSIIYMACGYLFCCYYGILYWVNRFTC 3445
Query 237 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+T GVY + VS E +YM + L PK + DA L+ KL+G+GG IK++TVQ
Sbjct 3446 MTCGVYQFTVSPAELKYMTANNLSAPKTAYDAMILSFKLMGIGGGRNIKISTVQ 3499
>sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=1a PE=1 SV=1
Length=4117
Score = 243 bits (619), Expect = 2e-71, Method: Composition-based stats.
Identities = 80/279 (29%), Positives = 135/279 (48%), Gaps = 12/279 (4%)
Query 14 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLP 73
LL+ + + ++ FF++ P + +S+ M +KHK F +FL+P
Sbjct 3311 LLVGSFLTF-FWSELVSYTKFFWVNPGYVTPMFACLSLLSSLLMFTLKHKTLFFQVFLIP 3369
Query 74 SLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTV-- 131
+L + N+ + + + SL GF + V V+ IL T
Sbjct 3370 ALIVTSCINLAFDVEVYNY--LAEHFDYHVSLMGFNAQGLVNIFVCFVVTILHGTYTWRF 3427
Query 132 YDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVF 191
++ A V ++ +LT Y +Y A D L SVT N V V + + V+
Sbjct 3428 FNTPASSVTYVVALLTAAYNYFY--ASDILSCAMTLFASVTGN--WFVGAVCY--KVAVY 3481
Query 192 MCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEF 251
M + + P F ++ +M Y LGYF C++G+ NR+F++++GVYDY VS EF
Sbjct 3482 MALRF-PTFVAIFGDIKSVMFCYLVLGYFTCCFYGILYWFNRFFKVSVGVYDYTVSAAEF 3540
Query 252 RYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+YM + GL P ++D+ L+ KL+G+GG+ IK+++VQ
Sbjct 3541 KYMVANGLRAPTGTLDSLLLSAKLIGIGGERNIKISSVQ 3579
>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=rep PE=1 SV=1
Length=6684
Score = 224 bits (572), Expect = 3e-65, Method: Composition-based stats.
Identities = 67/294 (23%), Positives = 131/294 (45%), Gaps = 13/294 (4%)
Query 7 IKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAF 66
+K + ++ + ++ ++ F ++ +S + +KHK F
Sbjct 3184 VKSFFYPIMTAMTILFAFWLEFFMYTPFTWINPTFVSIVLAVTTLISTVFVSGIKHKMLF 3243
Query 67 LCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILM 126
F+LPS+ V N+ + S+ + + ++ +T ++ ++ ++ +
Sbjct 3244 FMSFVLPSVILVTAHNLFW-DFSYYESLQSIVENTNTMFLPVDMQGVMLTVFCFIVFVTY 3302
Query 127 TAR------TVYDDGARRVWTLMNVLTLVYKVYYGNALDQA----ISMWALIISVTSNYS 176
+ R + + + + N++ + +Q ++M +I+S+T+
Sbjct 3303 SVRFFTCKQSWFSLAVTTILVIFNMVKIFGTSDEPWTENQIAFCFVNMLTMIVSLTTKDW 3362
Query 177 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 236
VV +A IV + F ++CI +VY GY CY+G+ +NR+
Sbjct 3363 MVVIASYRIAYYIVVCVMP--SAFVSDFGFMKCISIVYMACGYLFCCYYGILYWVNRFTC 3420
Query 237 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+T GVY + VS E +YM + L PKN+ DA L+ KL+GVGGK IK++TVQ
Sbjct 3421 MTCGVYQFTVSAAELKYMTANNLSAPKNAYDAMILSAKLIGVGGKRNIKISTVQ 3474
>sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=1a PE=1 SV=1
Length=4017
Score = 224 bits (571), Expect = 4e-65, Method: Composition-based stats.
Identities = 67/294 (23%), Positives = 131/294 (45%), Gaps = 13/294 (4%)
Query 7 IKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAF 66
+K + ++ + ++ ++ F ++ +S + +KHK F
Sbjct 3184 VKSFFYPIMTAMTILFAFWLEFFMYTPFTWINPTFVSIVLAVTTLISTVFVSGIKHKMLF 3243
Query 67 LCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILM 126
F+LPS+ V N+ + S+ + + ++ +T ++ ++ ++ +
Sbjct 3244 FMSFVLPSVILVTAHNLFW-DFSYYESLQSIVENTNTMFLPVDMQGVMLTVFCFIVFVTY 3302
Query 127 TAR------TVYDDGARRVWTLMNVLTLVYKVYYGNALDQA----ISMWALIISVTSNYS 176
+ R + + + + N++ + +Q ++M +I+S+T+
Sbjct 3303 SVRFFTCKQSWFSLAVTTILVIFNMVKIFGTSDEPWTENQIAFCFVNMLTMIVSLTTKDW 3362
Query 177 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 236
VV +A IV + F ++CI +VY GY CY+G+ +NR+
Sbjct 3363 MVVIASYRIAYYIVVCVMP--SAFVSDFGFMKCISIVYMACGYLFCCYYGILYWVNRFTC 3420
Query 237 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
+T GVY + VS E +YM + L PKN+ DA L+ KL+GVGGK IK++TVQ
Sbjct 3421 MTCGVYQFTVSAAELKYMTANNLSAPKNAYDAMILSAKLIGVGGKRNIKISTVQ 3474
>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793
Score = 222 bits (566), Expect = 2e-64, Method: Composition-based stats.
Identities = 77/271 (28%), Positives = 129/271 (48%), Gaps = 11/271 (4%)
Query 20 TSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVA 79
L L + S F++ P + II S+ M+ VKHK FL L+LLPSL V+
Sbjct 3331 LLFLFLSEMLNHSKLFWINPGYITPVFLAIIVASSALMLLVKHKLLFLQLYLLPSLCIVS 3390
Query 80 YFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRV 139
+N+ + + ++ D GF + + + ++ L T R + +
Sbjct 3391 GYNI-FKDYHFYTYMLEEFDY-KVPFGGFNVTGVLNISLCCFVMGLHTFRFL-QTPNKIF 3447
Query 140 WTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPI 199
++ VLT++Y YY + I S +NY + T LA ++
Sbjct 3448 SYVVAVLTVLYTYYYSTDVLGLILTSM---SGFTNYWFIGTATYKLATYVL-----PHTS 3499
Query 200 FFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGL 259
+ + ++ ++ +Y LGY Y+G +NR+ +LTLG Y++ VS EF+YM + GL
Sbjct 3500 LLDSFDAIKAVVFLYLLLGYCNCVYYGSLYWINRFCKLTLGCYEFKVSAAEFKYMVANGL 3559
Query 260 LPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
P DA L++KL+GVGG+ IK+++VQ
Sbjct 3560 RAPTGVFDALILSLKLIGVGGRKTIKISSVQ 3590
>sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus
512/2005 OX=693999 GN=1a PE=3 SV=1
Length=4128
Score = 222 bits (565), Expect = 3e-64, Method: Composition-based stats.
Identities = 77/271 (28%), Positives = 129/271 (48%), Gaps = 11/271 (4%)
Query 20 TSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVA 79
L L + S F++ P + II S+ M+ VKHK FL L+LLPSL V+
Sbjct 3331 LLFLFLSEMLNHSKLFWINPGYITPVFLAIIVASSALMLLVKHKLLFLQLYLLPSLCIVS 3390
Query 80 YFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRV 139
+N+ + + ++ D GF + + + ++ L T R + +
Sbjct 3391 GYNI-FKDYHFYTYMLEEFDY-KVPFGGFNVTGVLNISLCCFVMGLHTFRFL-QTPNKIF 3447
Query 140 WTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPI 199
++ VLT++Y YY + I S +NY + T LA ++
Sbjct 3448 SYVVAVLTVLYTYYYSTDVLGLILTSM---SGFTNYWFIGTATYKLATYVL-----PHTS 3499
Query 200 FFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGL 259
+ + ++ ++ +Y LGY Y+G +NR+ +LTLG Y++ VS EF+YM + GL
Sbjct 3500 LLDSFDAIKAVVFLYLLLGYCNCVYYGSLYWINRFCKLTLGCYEFKVSAAEFKYMVANGL 3559
Query 260 LPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 290
P DA L++KL+GVGG+ IK+++VQ
Sbjct 3560 RAPTGVFDALILSLKLIGVGGRKTIKISSVQ 3590
>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1
SV=1
Length=6629
Score = 184 bits (466), Expect = 4e-51, Method: Composition-based stats.
Identities = 74/305 (24%), Positives = 129/305 (42%), Gaps = 34/305 (11%)
Query 6 TIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHA 65
++ W + + L LF + ++ A+ ++ F VKH A
Sbjct 3089 FVRKATSWFWSRCVLA-CFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFTVKHVMA 3147
Query 66 FLCLFLLPSLATVAYFNMVYMP-------ASWVMRIMTWLDM--VDTSLSGFK------- 109
++ FLLP+L TV +P + V+ + W D DT +
Sbjct 3148 YMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPLVLYT 3207
Query 110 ----LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMW 165
++ C M + LL+L + ++T N LT + + +
Sbjct 3208 AFKCVQGCYMNSFNTSLLMLYQFVKL----GFVIYTSSNTLTAYTE------GNWELFFE 3257
Query 166 ALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYF 225
+ +V +N S +F+ + +M + YC ++ L +M+ +G+ CTCYF
Sbjct 3258 LVHTTVLANVSSNSLIGLFVFKCAKWM-LYYCNATYLNNYVLMAVMVN--CIGWLCTCYF 3314
Query 226 GLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIK 285
GL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G+GG +
Sbjct 3315 GLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLP 3374
Query 286 VATVQ 290
+ATVQ
Sbjct 3375 IATVQ 3379
>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep
PE=3 SV=1
Length=6629
Score = 184 bits (466), Expect = 4e-51, Method: Composition-based stats.
Identities = 74/305 (24%), Positives = 129/305 (42%), Gaps = 34/305 (11%)
Query 6 TIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHA 65
++ W + + L LF + ++ A+ ++ F VKH A
Sbjct 3089 FVRKATSWFWSRCVLA-CFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFTVKHVMA 3147
Query 66 FLCLFLLPSLATVAYFNMVYMP-------ASWVMRIMTWLDM--VDTSLSGFK------- 109
++ FLLP+L TV +P + V+ + W D DT +
Sbjct 3148 YMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPLVLYT 3207
Query 110 ----LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMW 165
++ C M + LL+L + ++T N LT + + +
Sbjct 3208 AFKCVQGCYMNSFNTSLLMLYQFVKL----GFVIYTSSNTLTAYTE------GNWELFFE 3257
Query 166 ALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYF 225
+ +V +N S +F+ + +M + YC ++ L +M+ +G+ CTCYF
Sbjct 3258 LVHTTVLANVSSNSLIGLFVFKCAKWM-LYYCNATYLNNYVLMAVMVN--CIGWLCTCYF 3314
Query 226 GLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIK 285
GL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G+GG +
Sbjct 3315 GLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLP 3374
Query 286 VATVQ 290
+ATVQ
Sbjct 3375 IATVQ 3379
>sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=1a PE=3
SV=1
Length=3951
Score = 182 bits (461), Expect = 2e-50, Method: Composition-based stats.
Identities = 74/305 (24%), Positives = 129/305 (42%), Gaps = 34/305 (11%)
Query 6 TIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHA 65
++ W + + L LF + ++ A+ ++ F VKH A
Sbjct 3089 FVRKATSWFWSRCVLA-CFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFTVKHVMA 3147
Query 66 FLCLFLLPSLATVAYFNMVYMP-------ASWVMRIMTWLDM--VDTSLSGFK------- 109
++ FLLP+L TV +P + V+ + W D DT +
Sbjct 3148 YMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPLVLYT 3207
Query 110 ----LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMW 165
++ C M + LL+L + ++T N LT + + +
Sbjct 3208 AFKCVQGCYMNSFNTSLLMLYQFVKL----GFVIYTSSNTLTAYTE------GNWELFFE 3257
Query 166 ALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYF 225
+ +V +N S +F+ + +M + YC ++ L +M+ +G+ CTCYF
Sbjct 3258 LVHTTVLANVSSNSLIGLFVFKCAKWM-LYYCNATYLNNYVLMAVMVN--CIGWLCTCYF 3314
Query 226 GLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIK 285
GL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G+GG +
Sbjct 3315 GLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLP 3374
Query 286 VATVQ 290
+ATVQ
Sbjct 3375 IATVQ 3379
>sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=1a PE=1 SV=1
Length=3951
Score = 182 bits (461), Expect = 2e-50, Method: Composition-based stats.
Identities = 74/305 (24%), Positives = 129/305 (42%), Gaps = 34/305 (11%)
Query 6 TIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHA 65
++ W + + L LF + ++ A+ ++ F VKH A
Sbjct 3089 FVRKATSWFWSRCVLA-CFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFTVKHVMA 3147
Query 66 FLCLFLLPSLATVAYFNMVYMP-------ASWVMRIMTWLDM--VDTSLSGFK------- 109
++ FLLP+L TV +P + V+ + W D DT +
Sbjct 3148 YMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPLVLYT 3207
Query 110 ----LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMW 165
++ C M + LL+L + ++T N LT + + +
Sbjct 3208 AFKCVQGCYMNSFNTSLLMLYQFVKL----GFVIYTSSNTLTAYTE------GNWELFFE 3257
Query 166 ALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYF 225
+ +V +N S +F+ + +M + YC ++ L +M+ +G+ CTCYF
Sbjct 3258 LVHTTVLANVSSNSLIGLFVFKCAKWM-LYYCNATYLNNYVLMAVMVN--CIGWLCTCYF 3314
Query 226 GLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIK 285
GL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G+GG +
Sbjct 3315 GLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLP 3374
Query 286 VATVQ 290
+ATVQ
Sbjct 3375 IATVQ 3379
>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631
Score = 179 bits (455), Expect = 1e-49, Method: Composition-based stats.
Identities = 75/305 (25%), Positives = 129/305 (42%), Gaps = 34/305 (11%)
Query 6 TIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHA 65
++ W + + L LF + ++ A+ ++ F VKH A
Sbjct 3091 FVRKATSWFWSRCVLA-CFLFVLCAIVLFTAVPLKFYVHAAVILLMAVLFISFTVKHVMA 3149
Query 66 FLCLFLLPSLATVAYFNMVYMP-------ASWVMRIMTWLDM--VDTSLSGFK------- 109
++ FLLP+L TV +P + V+ + W D DT +
Sbjct 3150 YMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMLLPLVLYT 3209
Query 110 ----LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMW 165
++ C M + LL+L + ++T N LT GN +
Sbjct 3210 AFKCVQGCYMNSFNTSLLMLYQFMKL----GFVIYTSSNTLTA---YTEGNWELFFELVH 3262
Query 166 ALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYF 225
++++ S+ S + V A+ +++ YC + L +M+ +G+ CTCYF
Sbjct 3263 TIVLANVSSNSLIGLIVFKCAKWMLY----YCNATYFNNYVLMAVMVN--GIGWLCTCYF 3316
Query 226 GLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIK 285
GL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G+GG +
Sbjct 3317 GLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKVNPPKTVWEVFTTNILIQGIGGDRVLP 3376
Query 286 VATVQ 290
+ATVQ
Sbjct 3377 IATVQ 3381
>sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=1a PE=1 SV=1
Length=3953
Score = 177 bits (448), Expect = 9e-49, Method: Composition-based stats.
Identities = 75/305 (25%), Positives = 129/305 (42%), Gaps = 34/305 (11%)
Query 6 TIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHA 65
++ W + + L LF + ++ A+ ++ F VKH A
Sbjct 3091 FVRKATSWFWSRCVLA-CFLFVLCAIVLFTAVPLKFYVHAAVILLMAVLFISFTVKHVMA 3149
Query 66 FLCLFLLPSLATVAYFNMVYMP-------ASWVMRIMTWLDM--VDTSLSGFK------- 109
++ FLLP+L TV +P + V+ + W D DT +
Sbjct 3150 YMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMLLPLVLYT 3209
Query 110 ----LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMW 165
++ C M + LL+L + ++T N LT GN +
Sbjct 3210 AFKCVQGCYMNSFNTSLLMLYQFMKL----GFVIYTSSNTLTA---YTEGNWELFFELVH 3262
Query 166 ALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYF 225
++++ S+ S + V A+ +++ YC + L +M+ +G+ CTCYF
Sbjct 3263 TIVLANVSSNSLIGLIVFKCAKWMLY----YCNATYFNNYVLMAVMVN--GIGWLCTCYF 3316
Query 226 GLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIK 285
GL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G+GG +
Sbjct 3317 GLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKVNPPKTVWEVFTTNILIQGIGGDRVLP 3376
Query 286 VATVQ 290
+ATVQ
Sbjct 3377 IATVQ 3381
>sp|Q8I7T3|SADA_DICDI Substrate-adhesion molecule OS=Dictyostelium
discoideum OX=44689 GN=sadA PE=2 SV=1
Length=952
Score = 31.9 bits (71), Expect = 9.4, Method: Composition-based stats.
Identities = 15/77 (19%), Positives = 26/77 (34%), Gaps = 0/77 (0%)
Query 65 AFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLI 124
L +FL+P L A + + W + L V + F ++ AS ++
Sbjct 683 LLLGVFLVPLLLAYAIISFMESLIHWKEVVTNRLIHVLVRILTFGYIGVLIAASFAMVTP 742
Query 125 LMTARTVYDDGARRVWT 141
L R + V
Sbjct 743 LHDYRIIIPGAIIFVLY 759
Lambda K H a alpha
0.318 0.137 0.383 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0418 0.140 1.90 42.6 43.6
Effective search space used: 24192043546
Search has CONVERGED!
Database: uniprot_sprot.fasta
Posted date: Apr 3, 2024 12:05 PM
Number of letters in database: 206,678,396
Number of sequences in database: 571,282
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40