PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,282 sequences; 206,678,396 total letters
Results from round 1
Query= YP_009725301.1 3C-like proteinase [Severe acute respiratory syndrome
coronavirus 2]
Length=306
Score E
Sequences producing significant alignments: (Bits) Value
sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute resp... 652 0.0
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re... 649 0.0
sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus 2... 635 0.0
sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respi... 634 0.0
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus... 632 0.0
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res... 631 0.0
sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus R... 630 0.0
sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus H... 630 0.0
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus... 628 0.0
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus... 628 0.0
sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus H... 342 8e-106
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus... 341 2e-105
sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respi... 322 7e-99
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res... 320 2e-98
sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus H... 311 3e-95
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus... 311 5e-95
sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus... 310 7e-95
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir... 310 9e-95
sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus H... 308 3e-94
sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus 1... 308 5e-94
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus... 308 5e-94
sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronaviru... 307 9e-94
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus... 307 1e-93
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi... 306 1e-93
sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronaviru... 305 3e-93
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi... 305 5e-93
sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus... 304 1e-92
sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus... 304 1e-92
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir... 303 2e-92
sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronaviru... 303 2e-92
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir... 303 2e-92
sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronaviru... 303 2e-92
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi... 303 3e-92
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi... 303 3e-92
sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus... 302 4e-92
sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus... 302 5e-92
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir... 302 5e-92
sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus... 302 5e-92
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir... 302 6e-92
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir... 301 7e-92
sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus... 298 2e-90
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir... 297 2e-90
sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus 5... 274 4e-82
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus... 273 4e-82
sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic ... 264 8e-79
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi... 263 2e-78
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir... 254 3e-75
sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmiss... 254 4e-75
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi... 253 4e-75
sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus... 250 4e-74
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir... 250 5e-74
sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus... 239 3e-70
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir... 238 6e-70
sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious ... 228 3e-66
sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious b... 228 3e-66
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou... 227 5e-66
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious... 227 5e-66
sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious b... 225 3e-65
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious... 224 5e-65
sp|Q8E919|FIEF_SHEON Cation-efflux pump FieF OS=Shewanella oneide... 33.5 2.4
sp|Q6AE15|HIS4_LEIXX 1-(5-phosphoribosyl)-5-[(5-phosphoribosylami... 33.1 2.6
>sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 PE=1 SV=1
Length=4405
Score = 652 bits (1681), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 306/306 (100%), Positives = 306/306 (100%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR
Sbjct 3264 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 3323
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3324 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 3383
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN
Sbjct 3384 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 3443
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3444 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3503
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC
Sbjct 3504 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 3563
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3564 SGVTFQ 3569
>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1
SV=1
Length=7096
Score = 649 bits (1674), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 306/306 (100%), Positives = 306/306 (100%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR
Sbjct 3264 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 3323
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3324 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 3383
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN
Sbjct 3384 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 3443
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3444 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3503
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC
Sbjct 3504 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 3563
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3564 SGVTFQ 3569
>sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus
279/2005 OX=389167 GN=1a PE=3 SV=1
Length=4388
Score = 635 bits (1639), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 294/306 (96%), Positives = 303/306 (99%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIR
Sbjct 3247 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3307 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN+TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3367 SPSGVYQCAMRPNYTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3427 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3487 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3546
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3547 SGVTFQ 3552
>sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respiratory
syndrome coronavirus OX=694009 GN=1a PE=1 SV=1
Length=4382
Score = 634 bits (1634), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 294/306 (96%), Positives = 302/306 (99%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIR
Sbjct 3241 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3300
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3301 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3541 SGVTFQ 3546
>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079
Score = 632 bits (1631), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 294/306 (96%), Positives = 303/306 (99%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIR
Sbjct 3247 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3307 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN+TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3367 SPSGVYQCAMRPNYTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3427 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3487 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3546
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3547 SGVTFQ 3552
>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score = 631 bits (1628), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 294/306 (96%), Positives = 302/306 (99%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIR
Sbjct 3241 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3300
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3301 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3541 SGVTFQ 3546
>sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus
Rp3/2004 OX=349344 GN=1a PE=3 SV=1
Length=4380
Score = 630 bits (1626), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 293/306 (96%), Positives = 301/306 (98%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIR
Sbjct 3239 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3298
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3299 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3358
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT VHAGTDLEG
Sbjct 3359 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTEVHAGTDLEGK 3418
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3419 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3478
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3479 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3538
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3539 SGVTFQ 3544
>sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus
HKU3 OX=442736 GN=1a PE=3 SV=1
Length=4376
Score = 630 bits (1626), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 292/306 (95%), Positives = 302/306 (99%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHV+CT+EDMLNPNY+DLLIR
Sbjct 3235 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVVCTAEDMLNPNYDDLLIR 3294
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3295 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3354
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3355 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3414
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3415 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3474
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3475 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3534
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3535 SGVTFQ 3540
>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071
Score = 628 bits (1620), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 293/306 (96%), Positives = 301/306 (98%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIR
Sbjct 3239 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3298
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3299 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3358
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT VHAGTDLEG
Sbjct 3359 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTEVHAGTDLEGK 3418
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3419 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3478
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3479 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3538
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3539 SGVTFQ 3544
>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067
Score = 628 bits (1620), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 292/306 (95%), Positives = 302/306 (99%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHV+CT+EDMLNPNY+DLLIR
Sbjct 3235 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVVCTAEDMLNPNYDDLLIR 3294
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3295 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3354
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3355 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3414
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3415 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3474
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3475 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3534
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3535 SGVTFQ 3540
>sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus
HKU9 OX=694006 GN=1a PE=3 SV=1
Length=4248
Score = 342 bits (876), Expect = 8e-106, Method: Compositional matrix adjust.
Identities = 159/306 (52%), Positives = 214/306 (70%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+G +MA PSG VE C+V+V G+ TLNG+WLD+ V CPRHV+C+ +++ NP+Y L +R
Sbjct 3104 AGLTRMAHPSGLVEPCLVKVNYGSMTLNGIWLDNFVICPRHVMCSRDELANPDYPRLSMR 3163
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+N++F V +RVIGH+M+ +LKL VD NPKTP Y F+R+ GQ S+LACY+G
Sbjct 3164 AANYDFHVSQNGHNIRVIGHTMEGSLLKLTVDVNNPKTPAYSFIRVSTGQAMSLLACYDG 3223
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P+GVY C +R N T++ SFL GSCGS GF ++ V FCY+H +ELP G H GTD G
Sbjct 3224 LPTGVYTCTLRSNGTMRASFLCGSCGSPGFVMNGKEVQFCYLHQLELPNGTHTGTDFSGV 3283
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPF D+Q Q A D TITVNVLAWLYAAV++G+ WFL + + + +FN A+KY +
Sbjct 3284 FYGPFEDKQVPQLAAPDCTITVNVLAWLYAAVLSGENWFLTKSSISPAEFNNCAVKYMCQ 3343
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+T + + +L PL+A+TGI+V M ++LK LL G GRTI+GS LEDE TP+D+ RQ
Sbjct 3344 SVTSESLQVLQPLAAKTGISVERMLSALKVLLSAGFCGRTIMGSCSLEDEHTPYDIGRQM 3403
Query 301 SGVTFQ 306
GV Q
Sbjct 3404 LGVKLQ 3409
>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930
Score = 341 bits (874), Expect = 2e-105, Method: Compositional matrix adjust.
Identities = 159/306 (52%), Positives = 214/306 (70%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+G +MA PSG VE C+V+V G+ TLNG+WLD+ V CPRHV+C+ +++ NP+Y L +R
Sbjct 3104 AGLTRMAHPSGLVEPCLVKVNYGSMTLNGIWLDNFVICPRHVMCSRDELANPDYPRLSMR 3163
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+N++F V +RVIGH+M+ +LKL VD NPKTP Y F+R+ GQ S+LACY+G
Sbjct 3164 AANYDFHVSQNGHNIRVIGHTMEGSLLKLTVDVNNPKTPAYSFIRVSTGQAMSLLACYDG 3223
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P+GVY C +R N T++ SFL GSCGS GF ++ V FCY+H +ELP G H GTD G
Sbjct 3224 LPTGVYTCTLRSNGTMRASFLCGSCGSPGFVMNGKEVQFCYLHQLELPNGTHTGTDFSGV 3283
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPF D+Q Q A D TITVNVLAWLYAAV++G+ WFL + + + +FN A+KY +
Sbjct 3284 FYGPFEDKQVPQLAAPDCTITVNVLAWLYAAVLSGENWFLTKSSISPAEFNNCAVKYMCQ 3343
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+T + + +L PL+A+TGI+V M ++LK LL G GRTI+GS LEDE TP+D+ RQ
Sbjct 3344 SVTSESLQVLQPLAAKTGISVERMLSALKVLLSAGFCGRTIMGSCSLEDEHTPYDIGRQM 3403
Query 301 SGVTFQ 306
GV Q
Sbjct 3404 LGVKLQ 3409
>sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respiratory
syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=1a PE=1 SV=1
Length=4391
Score = 322 bits (824), Expect = 7e-99, Method: Compositional matrix adjust.
Identities = 157/310 (51%), Positives = 207/310 (67%), Gaps = 8/310 (3%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM+ PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+ LLI
Sbjct 3248 SGLVKMSHPSGDVEACMVQVTCGSMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLIS 3307
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
+NH+F VQ LRV+GH+MQ +LKL VD ANP TP Y F ++PG FSVLAC
Sbjct 3308 MTNHSFSVQKHIGAPANLRVVGHAMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLAC 3367
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+G + MRPN+TIKGSFL GSCGSVG+ + ++FCYMH MEL G H G+
Sbjct 3368 YNGRPTGTFTVVMRPNYTIKGSFLCGSCGSVGYTKEGSVINFCYMHQMELANGTHTGSAF 3427
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F+D+Q Q TD +VNV+AWLYAA++NG WF+ T++ FN A+
Sbjct 3428 DGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALAN 3487
Query 238 NY-EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDV 296
+ E + VD+ L+ +TG+A+ + ++++L G G+ ILGS +LEDEFTP DV
Sbjct 3488 QFTEFVGTQSVDM---LAVKTGVAIEQLLYAIQQLY-TGFQGKQILGSTMLEDEFTPEDV 3543
Query 297 VRQCSGVTFQ 306
Q GV Q
Sbjct 3544 NMQIMGVVMQ 3553
>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=rep PE=1 SV=1
Length=7078
Score = 320 bits (821), Expect = 2e-98, Method: Compositional matrix adjust.
Identities = 157/310 (51%), Positives = 207/310 (67%), Gaps = 8/310 (3%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM+ PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+ LLI
Sbjct 3248 SGLVKMSHPSGDVEACMVQVTCGSMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLIS 3307
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
+NH+F VQ LRV+GH+MQ +LKL VD ANP TP Y F ++PG FSVLAC
Sbjct 3308 MTNHSFSVQKHIGAPANLRVVGHAMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLAC 3367
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+G + MRPN+TIKGSFL GSCGSVG+ + ++FCYMH MEL G H G+
Sbjct 3368 YNGRPTGTFTVVMRPNYTIKGSFLCGSCGSVGYTKEGSVINFCYMHQMELANGTHTGSAF 3427
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F+D+Q Q TD +VNV+AWLYAA++NG WF+ T++ FN A+
Sbjct 3428 DGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALAN 3487
Query 238 NY-EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDV 296
+ E + VD+ L+ +TG+A+ + ++++L G G+ ILGS +LEDEFTP DV
Sbjct 3488 QFTEFVGTQSVDM---LAVKTGVAIEQLLYAIQQLY-TGFQGKQILGSTMLEDEFTPEDV 3543
Query 297 VRQCSGVTFQ 306
Q GV Q
Sbjct 3544 NMQIMGVVMQ 3553
>sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus
HKU5 OX=694008 GN=1a PE=3 SV=1
Length=4481
Score = 311 bits (798), Expect = 3e-95, Method: Compositional matrix adjust.
Identities = 155/310 (50%), Positives = 208/310 (67%), Gaps = 8/310 (3%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KMA PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+ LL+
Sbjct 3339 SGLVKMAAPSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDALLVS 3398
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
K+N +F+VQ LRV+GH+M +LKL V++ANP+TP Y F ++PG +FSVLAC
Sbjct 3399 KTNLSFIVQKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFSVLAC 3458
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+GV+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H G
Sbjct 3459 YNGRPTGVFMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHTGCAF 3518
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F DRQ Q +D T+N++AWLYAA++NG WF+ T + FN AM
Sbjct 3519 DGVMYGAFEDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEWAMSN 3578
Query 238 NY-EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDV 296
+ E + VD+ L+ +TG++V + ++ + L G G+TILG+++LEDEFTP DV
Sbjct 3579 QFTEFIGTQSVDM---LAHKTGVSVEQLLYAI-QTLHKGFQGKTILGNSMLEDEFTPDDV 3634
Query 297 VRQCSGVTFQ 306
Q GV Q
Sbjct 3635 NMQVMGVVMQ 3644
>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182
Score = 311 bits (796), Expect = 5e-95, Method: Compositional matrix adjust.
Identities = 155/310 (50%), Positives = 208/310 (67%), Gaps = 8/310 (3%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KMA PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+ LL+
Sbjct 3339 SGLVKMAAPSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDALLVS 3398
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
K+N +F+VQ LRV+GH+M +LKL V++ANP+TP Y F ++PG +FSVLAC
Sbjct 3399 KTNLSFIVQKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFSVLAC 3458
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+GV+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H G
Sbjct 3459 YNGRPTGVFMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHTGCAF 3518
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F DRQ Q +D T+N++AWLYAA++NG WF+ T + FN AM
Sbjct 3519 DGVMYGAFEDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEWAMSN 3578
Query 238 NY-EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDV 296
+ E + VD+ L+ +TG++V + ++ + L G G+TILG+++LEDEFTP DV
Sbjct 3579 QFTEFIGTQSVDM---LAHKTGVSVEQLLYAI-QTLHKGFQGKTILGNSMLEDEFTPDDV 3634
Query 297 VRQCSGVTFQ 306
Q GV Q
Sbjct 3635 NMQVMGVVMQ 3644
>sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus
(strain 2) OX=76344 GN=1a PE=3 SV=1
Length=4416
Score = 310 bits (795), Expect = 7e-95, Method: Compositional matrix adjust.
Identities = 155/306 (51%), Positives = 200/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM FP+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R
Sbjct 3280 SGIVKMVFPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYSNLLCR 3339
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F V +G + L V+ + MQ +L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3340 VISSDFCVMSGRMSLTVMSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNG 3399
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3400 KSQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGN 3459
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D T TVNV+AWLYAA++N WF+ + +L +FN+ AM +
Sbjct 3460 FYGPYRDAQVVQLPVQDYTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFS 3519
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q
Sbjct 3520 SIKADLV--LDALASMTGVTVEQILAAIKRLY-SGFQGKQILGSCVLEDELTPSDVYQQL 3576
Query 301 SGVTFQ 306
+GV Q
Sbjct 3577 AGVKLQ 3582
>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124
Score = 310 bits (794), Expect = 9e-95, Method: Compositional matrix adjust.
Identities = 155/306 (51%), Positives = 200/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM FP+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R
Sbjct 3280 SGIVKMVFPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYSNLLCR 3339
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F V +G + L V+ + MQ +L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3340 VISSDFCVMSGRMSLTVMSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNG 3399
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3400 KSQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGN 3459
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D T TVNV+AWLYAA++N WF+ + +L +FN+ AM +
Sbjct 3460 FYGPYRDAQVVQLPVQDYTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFS 3519
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q
Sbjct 3520 SIKADLV--LDALASMTGVTVEQILAAIKRLY-SGFQGKQILGSCVLEDELTPSDVYQQL 3576
Query 301 SGVTFQ 306
+GV Q
Sbjct 3577 AGVKLQ 3582
>sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus
HKU4 OX=694007 GN=1a PE=1 SV=1
Length=4434
Score = 308 bits (790), Expect = 3e-94, Method: Compositional matrix adjust.
Identities = 154/310 (50%), Positives = 205/310 (66%), Gaps = 8/310 (3%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM+ PSG VE C+VQVTCG+ TLNGLWLD+ V+CPRH++C ++ + +PNY+ LLI
Sbjct 3292 SGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLIS 3351
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
K+NH+F+VQ LRV+ HSM +LKL VD ANP TP Y F ++PG +FSVLAC
Sbjct 3352 KTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLAC 3411
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+GV+ +R N TIKGSFL GSCGSVG+ + ++F YMH MEL G H G+
Sbjct 3412 YNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSF 3471
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F D+QT Q TD T+NV+AWLYAAV+NG +WF+ + +N A+
Sbjct 3472 DGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSN 3531
Query 238 NY-EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDV 296
+ E + +D+ L+ +TG++V M A+++ L G G+TILG + LEDEFTP DV
Sbjct 3532 QFTEFVGTQSIDM---LAHRTGVSVEQMLAAIQS-LHAGFQGKTILGQSTLEDEFTPDDV 3587
Query 297 VRQCSGVTFQ 306
Q GV Q
Sbjct 3588 NMQVMGVVMQ 3597
>sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus
133/2005 OX=389230 GN=1a PE=3 SV=1
Length=4441
Score = 308 bits (788), Expect = 5e-94, Method: Compositional matrix adjust.
Identities = 154/310 (50%), Positives = 205/310 (66%), Gaps = 8/310 (3%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM+ PSG VE C+VQVTCG+ TLNGLWLD+ V+CPRH++C ++ + +PNY+ LLI
Sbjct 3299 SGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLIS 3358
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
K+NH+F+VQ LRV+ HSM +LKL VD ANP TP Y F ++PG +FSVLAC
Sbjct 3359 KTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLAC 3418
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+GV+ +R N TIKGSFL GSCGSVG+ + ++F YMH MEL G H G+
Sbjct 3419 YNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVLNFVYMHQMELSNGTHTGSSF 3478
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F D+QT Q TD T+NV+AWLYAAV+NG +WF+ + +N A+
Sbjct 3479 DGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSN 3538
Query 238 NY-EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDV 296
+ E + +D+ L+ +TG++V M A+++ L G G+TILG + LEDEFTP DV
Sbjct 3539 QFTEFVGTQSIDM---LAHRTGVSVEQMLAAIQS-LHAGFQGKTILGQSTLEDEFTPDDV 3594
Query 297 VRQCSGVTFQ 306
Q GV Q
Sbjct 3595 NMQVMGVVMQ 3604
>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119
Score = 308 bits (788), Expect = 5e-94, Method: Compositional matrix adjust.
Identities = 154/310 (50%), Positives = 205/310 (66%), Gaps = 8/310 (3%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM+ PSG VE C+VQVTCG+ TLNGLWLD+ V+CPRH++C ++ + +PNY+ LLI
Sbjct 3292 SGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLIS 3351
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
K+NH+F+VQ LRV+ HSM +LKL VD ANP TP Y F ++PG +FSVLAC
Sbjct 3352 KTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLAC 3411
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+GV+ +R N TIKGSFL GSCGSVG+ + ++F YMH MEL G H G+
Sbjct 3412 YNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSF 3471
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F D+QT Q TD T+NV+AWLYAAV+NG +WF+ + +N A+
Sbjct 3472 DGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSN 3531
Query 238 NY-EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDV 296
+ E + +D+ L+ +TG++V M A+++ L G G+TILG + LEDEFTP DV
Sbjct 3532 QFTEFVGTQSIDM---LAHRTGVSVEQMLAAIQS-LHAGFQGKTILGQSTLEDEFTPDDV 3587
Query 297 VRQCSGVTFQ 306
Q GV Q
Sbjct 3588 NMQVMGVVMQ 3597
>sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronavirus
(strain JHM) OX=11144 GN=1a PE=1 SV=1
Length=4474
Score = 307 bits (786), Expect = 9e-94, Method: Compositional matrix adjust.
Identities = 154/306 (50%), Positives = 199/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R
Sbjct 3337 SGIVKMVSPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCR 3396
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + + L V+ + MQ +L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3397 VTSSDFCVMSDRMSLTVMSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNG 3456
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR + TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3457 RPQGAFHVVMRSSHTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGN 3516
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D T TVNV+AWLYAA++N WF+ + +L +FN+ AM +
Sbjct 3517 FYGPYRDAQVVQLPVQDYTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFS 3576
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q
Sbjct 3577 SIKADLV--LDALASMTGVTVEQVLAAIKR-LHSGFQGKQILGSCVLEDELTPSDVYQQL 3633
Query 301 SGVTFQ 306
+GV Q
Sbjct 3634 AGVKLQ 3639
>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126
Score = 307 bits (786), Expect = 1e-93, Method: Compositional matrix adjust.
Identities = 154/310 (50%), Positives = 205/310 (66%), Gaps = 8/310 (3%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM+ PSG VE C+VQVTCG+ TLNGLWLD+ V+CPRH++C ++ + +PNY+ LLI
Sbjct 3299 SGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLIS 3358
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
K+NH+F+VQ LRV+ HSM +LKL VD ANP TP Y F ++PG +FSVLAC
Sbjct 3359 KTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLAC 3418
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+GV+ +R N TIKGSFL GSCGSVG+ + ++F YMH MEL G H G+
Sbjct 3419 YNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVLNFVYMHQMELSNGTHTGSSF 3478
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F D+QT Q TD T+NV+AWLYAAV+NG +WF+ + +N A+
Sbjct 3479 DGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSN 3538
Query 238 NY-EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDV 296
+ E + +D+ L+ +TG++V M A+++ L G G+TILG + LEDEFTP DV
Sbjct 3539 QFTEFVGTQSIDM---LAHRTGVSVEQMLAAIQS-LHAGFQGKTILGQSTLEDEFTPDDV 3594
Query 297 VRQCSGVTFQ 306
Q GV Q
Sbjct 3595 NMQVMGVVMQ 3604
>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180
Score = 306 bits (785), Expect = 1e-93, Method: Compositional matrix adjust.
Identities = 154/306 (50%), Positives = 199/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R
Sbjct 3337 SGIVKMVSPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCR 3396
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + + L V+ + MQ +L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3397 VTSSDFCVMSDRMSLTVMSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNG 3456
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR + TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3457 RPQGAFHVVMRSSHTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGN 3516
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D T TVNV+AWLYAA++N WF+ + +L +FN+ AM +
Sbjct 3517 FYGPYRDAQVVQLPVQDYTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFS 3576
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q
Sbjct 3577 SIKADLV--LDALASMTGVTVEQVLAAIKR-LHSGFQGKQILGSCVLEDELTPSDVYQQL 3633
Query 301 SGVTFQ 306
+GV Q
Sbjct 3634 AGVKLQ 3639
>sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronavirus
(strain A59) OX=11142 GN=1a PE=1 SV=1
Length=4468
Score = 305 bits (782), Expect = 3e-93, Method: Compositional matrix adjust.
Identities = 155/306 (51%), Positives = 199/306 (65%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R
Sbjct 3334 SGIVKMVSPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCR 3393
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3394 VTSSDFCVMSGRMSLTVMSYQMQGCQLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNG 3453
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + +R + TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3454 RPQGAFHVTLRSSHTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGN 3513
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D T TVNV+AWLYAA+ N WF+ + +L +FN+ AM +
Sbjct 3514 FYGPYRDAQVVQLPVQDYTQTVNVVAWLYAAIFNRCNWFVQSDSCSLEEFNVWAMTNGFS 3573
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q
Sbjct 3574 SIKADLV--LDALASMTGVTVEQVLAAIKR-LHSGFQGKQILGSCVLEDE-TPSDVYQQL 3629
Query 301 SGVTFQ 306
+GV Q
Sbjct 3630 AGVKLQ 3635
>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176
Score = 305 bits (781), Expect = 5e-93, Method: Compositional matrix adjust.
Identities = 155/306 (51%), Positives = 199/306 (65%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R
Sbjct 3334 SGIVKMVSPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCR 3393
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3394 VTSSDFCVMSGRMSLTVMSYQMQGCQLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNG 3453
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + +R + TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3454 RPQGAFHVTLRSSHTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGN 3513
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D T TVNV+AWLYAA+ N WF+ + +L +FN+ AM +
Sbjct 3514 FYGPYRDAQVVQLPVQDYTQTVNVVAWLYAAIFNRCNWFVQSDSCSLEEFNVWAMTNGFS 3573
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q
Sbjct 3574 SIKADLV--LDALASMTGVTVEQVLAAIKR-LHSGFQGKQILGSCVLEDE-TPSDVYQQL 3629
Query 301 SGVTFQ 306
+GV Q
Sbjct 3630 AGVKLQ 3635
>sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus
OC43 OX=31631 GN=1a PE=1 SV=1
Length=4383
Score = 304 bits (778), Expect = 1e-92, Method: Compositional matrix adjust.
Identities = 148/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + M+ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMRGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN LAWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPIQDYIQSVNFLAWLYAAILNNCNWFIQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=1a PE=3 SV=1
Length=4383
Score = 304 bits (778), Expect = 1e-92, Method: Compositional matrix adjust.
Identities = 148/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059
Score = 303 bits (777), Expect = 2e-92, Method: Compositional matrix adjust.
Identities = 148/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=1a PE=3 SV=1
Length=4383
Score = 303 bits (777), Expect = 2e-92, Method: Compositional matrix adjust.
Identities = 147/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095
Score = 303 bits (777), Expect = 2e-92, Method: Compositional matrix adjust.
Identities = 148/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + M+ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMRGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN LAWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPIQDYIQSVNFLAWLYAAILNNCNWFIQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=1a PE=3 SV=1
Length=4383
Score = 303 bits (776), Expect = 2e-92, Method: Compositional matrix adjust.
Identities = 147/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094
Score = 303 bits (775), Expect = 3e-92, Method: Compositional matrix adjust.
Identities = 147/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094
Score = 303 bits (775), Expect = 3e-92, Method: Compositional matrix adjust.
Identities = 147/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=1a PE=3 SV=1
Length=4421
Score = 302 bits (774), Expect = 4e-92, Method: Compositional matrix adjust.
Identities = 150/306 (49%), Positives = 193/306 (63%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R
Sbjct 3285 SGIVKMVSPTSKIEPCLVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCR 3344
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F + +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3345 VTLGDFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNG 3404
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3405 RPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFNGN 3464
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM +
Sbjct 3465 FYGPYRDAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFS 3524
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q
Sbjct 3525 QVKADLV--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQL 3581
Query 301 SGVTFQ 306
+GV Q
Sbjct 3582 AGVKLQ 3587
>sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=1a PE=1 SV=1
Length=4471
Score = 302 bits (774), Expect = 5e-92, Method: Compositional matrix adjust.
Identities = 150/306 (49%), Positives = 193/306 (63%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC+S +M P+Y LL R
Sbjct 3335 SGIVKMVSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICSSSNMNEPDYSALLCR 3394
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F + +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3395 VTLGDFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGNVKPGETFTVLAAYNG 3454
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3455 RPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGN 3514
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D TVNV+AWLYAA++N WF+ + DFN+ AM +
Sbjct 3515 FYGPYRDAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSTEDFNVWAMANGFS 3574
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q
Sbjct 3575 QVKADLV--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQL 3631
Query 301 SGVTFQ 306
+GV Q
Sbjct 3632 AGVKLQ 3637
>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132
Score = 302 bits (773), Expect = 5e-92, Method: Compositional matrix adjust.
Identities = 150/306 (49%), Positives = 193/306 (63%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R
Sbjct 3285 SGIVKMVSPTSKIEPCLVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCR 3344
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F + +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3345 VTLGDFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNG 3404
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3405 RPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFNGN 3464
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM +
Sbjct 3465 FYGPYRDAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFS 3524
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q
Sbjct 3525 QVKADLV--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQL 3581
Query 301 SGVTFQ 306
+GV Q
Sbjct 3582 AGVKLQ 3587
>sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=1a PE=3 SV=1
Length=4441
Score = 302 bits (773), Expect = 5e-92, Method: Compositional matrix adjust.
Identities = 150/306 (49%), Positives = 193/306 (63%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R
Sbjct 3305 SGIVKMVSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCR 3364
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F + +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3365 VTLGDFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNG 3424
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3425 RPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGN 3484
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM +
Sbjct 3485 FYGPYRDAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFS 3544
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q
Sbjct 3545 QVKADLV--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQL 3601
Query 301 SGVTFQ 306
+GV Q
Sbjct 3602 AGVKLQ 3607
>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182
Score = 302 bits (773), Expect = 6e-92, Method: Compositional matrix adjust.
Identities = 150/306 (49%), Positives = 193/306 (63%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC+S +M P+Y LL R
Sbjct 3335 SGIVKMVSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICSSSNMNEPDYSALLCR 3394
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F + +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3395 VTLGDFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGNVKPGETFTVLAAYNG 3454
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3455 RPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGN 3514
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D TVNV+AWLYAA++N WF+ + DFN+ AM +
Sbjct 3515 FYGPYRDAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSTEDFNVWAMANGFS 3574
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q
Sbjct 3575 QVKADLV--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQL 3631
Query 301 SGVTFQ 306
+GV Q
Sbjct 3632 AGVKLQ 3637
>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152
Score = 301 bits (772), Expect = 7e-92, Method: Compositional matrix adjust.
Identities = 150/306 (49%), Positives = 193/306 (63%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R
Sbjct 3305 SGIVKMVSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCR 3364
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F + +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3365 VTLGDFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNG 3424
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3425 RPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGN 3484
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM +
Sbjct 3485 FYGPYRDAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFS 3544
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q
Sbjct 3545 QVKADLV--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQL 3601
Query 301 SGVTFQ 306
+GV Q
Sbjct 3602 AGVKLQ 3607
>sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=1a PE=3 SV=1
Length=4383
Score = 298 bits (762), Expect = 2e-90, Method: Compositional matrix adjust.
Identities = 146/306 (48%), Positives = 196/306 (64%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWL D VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLGDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSV + I DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVVYVIMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKH-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094
Score = 297 bits (761), Expect = 2e-90, Method: Compositional matrix adjust.
Identities = 146/306 (48%), Positives = 196/306 (64%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWL D VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLGDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSV + I DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVVYVIMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKH-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus
512/2005 OX=693999 GN=1a PE=3 SV=1
Length=4128
Score = 274 bits (700), Expect = 4e-82, Method: Compositional matrix adjust.
Identities = 140/307 (46%), Positives = 205/307 (67%), Gaps = 6/307 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLI 59
+G RKMA PSG VEGC+V+V+ G TLNGLWL D V CPRHVI + + ++++ ++ L+
Sbjct 3013 AGLRKMAQPSGIVEGCIVRVSYGNLTLNGLWLGDTVICPRHVIASNTTNVIDYDHAMSLV 3072
Query 60 RKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
R HNF + +GN+ L VI SM+ +L +KV+ +N TP Y + ++PG +F++LACY+
Sbjct 3073 RL--HNFSISSGNMFLGVISASMRGTLLHIKVNQSNVNTPNYTYKVLKPGDSFNILACYD 3130
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
GS +GVY MR N+TI+GSF++G+CGS G+NI+ V FCYMHH+EL +G H G+D++G
Sbjct 3131 GSAAGVYGVNMRTNYTIRGSFISGACGSPGYNINNGVVEFCYMHHLELGSGCHVGSDMDG 3190
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 239
YG + D+ T Q G +T NV +WLY A+INGDRW+L+ + ++ +N A++
Sbjct 3191 TMYGKYEDQPTLQIEGASNLVTENVCSWLYGALINGDRWWLSSVSVGVDTYNEWALRNGM 3250
Query 240 EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQ 299
L +VD L A+TG+ V + AS+++L N G++ILG L DEFT +VV+Q
Sbjct 3251 TAL--KNVDCFSLLVAKTGVDVGRLLASIQKLHGN-FGGKSILGCTSLCDEFTLSEVVKQ 3307
Query 300 CSGVTFQ 306
GVT Q
Sbjct 3308 MYGVTLQ 3314
>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793
Score = 273 bits (699), Expect = 4e-82, Method: Compositional matrix adjust.
Identities = 140/307 (46%), Positives = 205/307 (67%), Gaps = 6/307 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLI 59
+G RKMA PSG VEGC+V+V+ G TLNGLWL D V CPRHVI + + ++++ ++ L+
Sbjct 3013 AGLRKMAQPSGIVEGCIVRVSYGNLTLNGLWLGDTVICPRHVIASNTTNVIDYDHAMSLV 3072
Query 60 RKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
R HNF + +GN+ L VI SM+ +L +KV+ +N TP Y + ++PG +F++LACY+
Sbjct 3073 RL--HNFSISSGNMFLGVISASMRGTLLHIKVNQSNVNTPNYTYKVLKPGDSFNILACYD 3130
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
GS +GVY MR N+TI+GSF++G+CGS G+NI+ V FCYMHH+EL +G H G+D++G
Sbjct 3131 GSAAGVYGVNMRTNYTIRGSFISGACGSPGYNINNGVVEFCYMHHLELGSGCHVGSDMDG 3190
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 239
YG + D+ T Q G +T NV +WLY A+INGDRW+L+ + ++ +N A++
Sbjct 3191 TMYGKYEDQPTLQIEGASNLVTENVCSWLYGALINGDRWWLSSVSVGVDTYNEWALRNGM 3250
Query 240 EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQ 299
L +VD L A+TG+ V + AS+++L N G++ILG L DEFT +VV+Q
Sbjct 3251 TAL--KNVDCFSLLVAKTGVDVGRLLASIQKLHGN-FGGKSILGCTSLCDEFTLSEVVKQ 3307
Query 300 CSGVTFQ 306
GVT Q
Sbjct 3308 MYGVTLQ 3314
>sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=1a PE=1 SV=1
Length=4117
Score = 264 bits (675), Expect = 8e-79, Method: Compositional matrix adjust.
Identities = 138/307 (45%), Positives = 198/307 (64%), Gaps = 6/307 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSE-DMLNPNYEDLLI 59
+G RKMA PSG VE C+V+V G LNGLWL D+V CPRHVI +S ++ +Y ++
Sbjct 2998 AGLRKMAQPSGVVEKCIVRVCYGNMALNGLWLGDIVMCPRHVIASSTTSTIDYDYALSVL 3057
Query 60 RKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
R HNF + +GNV L V+ +M+ +L++KV+ N TPKY + ++PG++F++LACY+
Sbjct 3058 RL--HNFSISSGNVFLGVVSATMRGALLQIKVNQNNVHTPKYTYRTVRPGESFNILACYD 3115
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
G+ +GVY MR N+TI+GSF+NG+CGS G+NI+ V FCY+H +EL +G H G+DL+G
Sbjct 3116 GAAAGVYGVNMRSNYTIRGSFINGACGSPGYNINNGTVEFCYLHQLELGSGCHVGSDLDG 3175
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 239
YG + D+ T Q G + T NVLA+LYAA+ING W+L+ ++ FN A+
Sbjct 3176 VMYGGYEDQPTLQVEGASSLFTENVLAFLYAALINGSTWWLSSSRIAVDRFNEWAVHNGM 3235
Query 240 EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQ 299
T + D L+A+TG+ V + AS++ L +N G+ ILG L DEFT +VVRQ
Sbjct 3236 T--TVGNTDCFSILAAKTGVDVQRLLASIQSLHKN-FGGKQILGHTSLTDEFTTGEVVRQ 3292
Query 300 CSGVTFQ 306
GV Q
Sbjct 3293 MYGVNLQ 3299
>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781
Score = 263 bits (672), Expect = 2e-78, Method: Compositional matrix adjust.
Identities = 138/307 (45%), Positives = 198/307 (64%), Gaps = 6/307 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSE-DMLNPNYEDLLI 59
+G RKMA PSG VE C+V+V G LNGLWL D+V CPRHVI +S ++ +Y ++
Sbjct 2998 AGLRKMAQPSGVVEKCIVRVCYGNMALNGLWLGDIVMCPRHVIASSTTSTIDYDYALSVL 3057
Query 60 RKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
R HNF + +GNV L V+ +M+ +L++KV+ N TPKY + ++PG++F++LACY+
Sbjct 3058 RL--HNFSISSGNVFLGVVSATMRGALLQIKVNQNNVHTPKYTYRTVRPGESFNILACYD 3115
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
G+ +GVY MR N+TI+GSF+NG+CGS G+NI+ V FCY+H +EL +G H G+DL+G
Sbjct 3116 GAAAGVYGVNMRSNYTIRGSFINGACGSPGYNINNGTVEFCYLHQLELGSGCHVGSDLDG 3175
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 239
YG + D+ T Q G + T NVLA+LYAA+ING W+L+ ++ FN A+
Sbjct 3176 VMYGGYEDQPTLQVEGASSLFTENVLAFLYAALINGSTWWLSSSRIAVDRFNEWAVHNGM 3235
Query 240 EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQ 299
T + D L+A+TG+ V + AS++ L +N G+ ILG L DEFT +VVRQ
Sbjct 3236 T--TVGNTDCFSILAAKTGVDVQRLLASIQSLHKN-FGGKQILGHTSLTDEFTTGEVVRQ 3292
Query 300 CSGVTFQ 306
GV Q
Sbjct 3293 MYGVNLQ 3299
>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709
Score = 254 bits (648), Expect = 3e-75, Method: Compositional matrix adjust.
Identities = 135/306 (44%), Positives = 183/306 (60%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG RKMA PSG VE C+V+V G LNGLWL D V CPRHVI + + NYE+ L
Sbjct 2904 SGLRKMAQPSGVVEPCIVRVAYGNNVLNGLWLGDEVICPRHVIASDTSRV-INYENELSS 2962
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF + N L V+ + L LKV+ NP TP++KF ++PG++F++LACY G
Sbjct 2963 VRLHNFSIAKNNAFLGVVSAKYKGVNLVLKVNQVNPNTPEHKFKSVRPGESFNILACYEG 3022
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++LEG
Sbjct 3023 CPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGTLYFVYMHHLELGNGSHVGSNLEGE 3082
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + TL +N A ++
Sbjct 3083 MYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMTLESYNAWAKTNSFT 3142
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D L+A+TG +V + + L G GRTIL L DEFTP +V+RQ
Sbjct 3143 EIVS--TDAFNMLAAKTGYSVEKLLECIVR-LNKGFGGRTILSYGSLCDEFTPTEVIRQM 3199
Query 301 SGVTFQ 306
GV Q
Sbjct 3200 YGVNLQ 3205
>sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=1a PE=1 SV=1
Length=4017
Score = 254 bits (648), Expect = 4e-75, Method: Compositional matrix adjust.
Identities = 137/306 (45%), Positives = 185/306 (60%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG RKMA PSG VE C+V+V+ G LNGLWL D V CPRHVI S+ NYE+ +
Sbjct 2879 SGLRKMAQPSGLVEPCIVRVSYGNNVLNGLWLGDEVICPRHVI-ASDTTRVINYENEMSS 2937
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF V NV L V+ + L LKV+ NP TP++KF I+ G++F++LACY G
Sbjct 2938 VRLHNFSVSKNNVFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIKAGESFNILACYEG 2997
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++ EG
Sbjct 2998 CPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLELGNGSHVGSNFEGE 3057
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + +L +N A ++
Sbjct 3058 MYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSLESYNTWAKTNSFT 3117
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
L+ D L+A+TG +V + S+ L G GRTIL L DEFTP +V+RQ
Sbjct 3118 ELSS--TDAFSMLAAKTGQSVEKLLDSIVR-LNKGFGGRTILSYGSLCDEFTPTEVIRQM 3174
Query 301 SGVTFQ 306
GV Q
Sbjct 3175 YGVNLQ 3180
>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=rep PE=1 SV=1
Length=6684
Score = 253 bits (647), Expect = 4e-75, Method: Compositional matrix adjust.
Identities = 137/306 (45%), Positives = 185/306 (60%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG RKMA PSG VE C+V+V+ G LNGLWL D V CPRHVI S+ NYE+ +
Sbjct 2879 SGLRKMAQPSGLVEPCIVRVSYGNNVLNGLWLGDEVICPRHVI-ASDTTRVINYENEMSS 2937
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF V NV L V+ + L LKV+ NP TP++KF I+ G++F++LACY G
Sbjct 2938 VRLHNFSVSKNNVFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIKAGESFNILACYEG 2997
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++ EG
Sbjct 2998 CPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLELGNGSHVGSNFEGE 3057
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + +L +N A ++
Sbjct 3058 MYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSLESYNTWAKTNSFT 3117
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
L+ D L+A+TG +V + S+ L G GRTIL L DEFTP +V+RQ
Sbjct 3118 ELSS--TDAFSMLAAKTGQSVEKLLDSIVR-LNKGFGGRTILSYGSLCDEFTPTEVIRQM 3174
Query 301 SGVTFQ 306
GV Q
Sbjct 3175 YGVNLQ 3180
>sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus
NL63 OX=277944 GN=1a PE=1 SV=1
Length=4060
Score = 250 bits (639), Expect = 4e-74, Method: Compositional matrix adjust.
Identities = 136/307 (44%), Positives = 192/307 (63%), Gaps = 5/307 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG +KMA PSG VE C+V+V G+T LNG+WL D V CPRHVI S +L +Y+
Sbjct 2940 SGLKKMAQPSGCVERCVVRVCYGSTVLNGVWLGDTVTCPRHVIAPSTTVL-IDYDHAYST 2998
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF V V L V+G +M VL++KV +N TPK+ F ++PG +F++LACY G
Sbjct 2999 MRLHNFSVSHNGVFLGVVGVTMHGSVLRIKVSQSNVHTPKHVFKTLKPGDSFNILACYEG 3058
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYD-CVSFCYMHHMELPTGVHAGTDLEG 179
SGV+ +R NFTIKGSF+NG+CGS G+N+ D V FCY+H +EL +G H G+D G
Sbjct 3059 IASGVFGVNLRTNFTIKGSFINGACGSPGYNVRNDGTVEFCYLHQIELGSGAHVGSDFTG 3118
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 239
+ YG F D+ + Q + ++ NV+A+LYAA++NG RW+L ++ FN AM Y
Sbjct 3119 SVYGNFDDQPSLQVESANLMLSDNVVAFLYAALLNGCRWWLCSTRVNVDGFNEWAMANGY 3178
Query 240 EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQ 299
++ V+ L+A+TG++V + AS++ L G G+ ILG + L DEFT +VV+Q
Sbjct 3179 TSVSS--VECYSILAAKTGVSVEQLLASIQH-LHEGFGGKNILGYSSLCDEFTLAEVVKQ 3235
Query 300 CSGVTFQ 306
GV Q
Sbjct 3236 MYGVNLQ 3242
>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729
Score = 250 bits (639), Expect = 5e-74, Method: Compositional matrix adjust.
Identities = 136/307 (44%), Positives = 192/307 (63%), Gaps = 5/307 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG +KMA PSG VE C+V+V G+T LNG+WL D V CPRHVI S +L +Y+
Sbjct 2940 SGLKKMAQPSGCVERCVVRVCYGSTVLNGVWLGDTVTCPRHVIAPSTTVL-IDYDHAYST 2998
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF V V L V+G +M VL++KV +N TPK+ F ++PG +F++LACY G
Sbjct 2999 MRLHNFSVSHNGVFLGVVGVTMHGSVLRIKVSQSNVHTPKHVFKTLKPGDSFNILACYEG 3058
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYD-CVSFCYMHHMELPTGVHAGTDLEG 179
SGV+ +R NFTIKGSF+NG+CGS G+N+ D V FCY+H +EL +G H G+D G
Sbjct 3059 IASGVFGVNLRTNFTIKGSFINGACGSPGYNVRNDGTVEFCYLHQIELGSGAHVGSDFTG 3118
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 239
+ YG F D+ + Q + ++ NV+A+LYAA++NG RW+L ++ FN AM Y
Sbjct 3119 SVYGNFDDQPSLQVESANLMLSDNVVAFLYAALLNGCRWWLCSTRVNVDGFNEWAMANGY 3178
Query 240 EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQ 299
++ V+ L+A+TG++V + AS++ L G G+ ILG + L DEFT +VV+Q
Sbjct 3179 TSVSS--VECYSILAAKTGVSVEQLLASIQH-LHEGFGGKNILGYSSLCDEFTLAEVVKQ 3235
Query 300 CSGVTFQ 306
GV Q
Sbjct 3236 MYGVNLQ 3242
>sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus
229E OX=11137 GN=1a PE=1 SV=1
Length=4085
Score = 239 bits (611), Expect = 3e-70, Method: Compositional matrix adjust.
Identities = 126/307 (41%), Positives = 188/307 (61%), Gaps = 6/307 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLI 59
+G RKMA PSG VE C+V+V G T LNGLWL D+VYCPRHVI + + ++ ++E ++
Sbjct 2966 AGLRKMAQPSGFVEKCVVRVCYGNTVLNGLWLGDIVYCPRHVIASNTTSAIDYDHEYSIM 3025
Query 60 RKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
R HNF + +G L V+G +M LK+KV N TP++ F ++ G+ F++LACY+
Sbjct 3026 RL--HNFSIISGTAFLGVVGATMHGVTLKIKVSQTNMHTPRHSFRTLKSGEGFNILACYD 3083
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
G GV+ MR N+TI+GSF+NG+CGS G+N+ V F YMH +EL +G H G+ +G
Sbjct 3084 GCAQGVFGVNMRTNWTIRGSFINGACGSPGYNLKNGEVEFVYMHQIELGSGSHVGSSFDG 3143
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 239
YG F D+ Q + +TVNV+A+LYAA++NG W+L + +N A +
Sbjct 3144 VMYGGFEDQPNLQVESANQMLTVNVVAFLYAAILNGCTWWLKGEKLFVEHYNEWAQANGF 3203
Query 240 EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQ 299
+ + D L+A+TG+ V + ++ ++L NG G+ ILG + L DEF+ +VV+Q
Sbjct 3204 TAMNGE--DAFSILAAKTGVCVERLLHAI-QVLNNGFGGKQILGYSSLNDEFSINEVVKQ 3260
Query 300 CSGVTFQ 306
GV Q
Sbjct 3261 MFGVNLQ 3267
>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus
229E OX=11137 GN=rep PE=1 SV=1
Length=6758
Score = 238 bits (608), Expect = 6e-70, Method: Compositional matrix adjust.
Identities = 126/307 (41%), Positives = 188/307 (61%), Gaps = 6/307 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLI 59
+G RKMA PSG VE C+V+V G T LNGLWL D+VYCPRHVI + + ++ ++E ++
Sbjct 2966 AGLRKMAQPSGFVEKCVVRVCYGNTVLNGLWLGDIVYCPRHVIASNTTSAIDYDHEYSIM 3025
Query 60 RKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
R HNF + +G L V+G +M LK+KV N TP++ F ++ G+ F++LACY+
Sbjct 3026 RL--HNFSIISGTAFLGVVGATMHGVTLKIKVSQTNMHTPRHSFRTLKSGEGFNILACYD 3083
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
G GV+ MR N+TI+GSF+NG+CGS G+N+ V F YMH +EL +G H G+ +G
Sbjct 3084 GCAQGVFGVNMRTNWTIRGSFINGACGSPGYNLKNGEVEFVYMHQIELGSGSHVGSSFDG 3143
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 239
YG F D+ Q + +TVNV+A+LYAA++NG W+L + +N A +
Sbjct 3144 VMYGGFEDQPNLQVESANQMLTVNVVAFLYAAILNGCTWWLKGEKLFVEHYNEWAQANGF 3203
Query 240 EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQ 299
+ + D L+A+TG+ V + ++ ++L NG G+ ILG + L DEF+ +VV+Q
Sbjct 3204 TAMNGE--DAFSILAAKTGVCVERLLHAI-QVLNNGFGGKQILGYSSLNDEFSINEVVKQ 3260
Query 300 CSGVTFQ 306
GV Q
Sbjct 3261 MFGVNLQ 3267
>sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=1a PE=3
SV=1
Length=3951
Score = 228 bits (581), Expect = 3e-66, Method: Compositional matrix adjust.
Identities = 131/317 (41%), Positives = 179/317 (56%), Gaps = 21/317 (7%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLI 59
SGF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ S D N D+L
Sbjct 2780 SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIYCPRHVLGKFSGDQWN----DVLN 2835
Query 60 RKSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACY 118
+NH F V + V L V+ ++ VL L+ AN +TPKYKF++ G +F++ Y
Sbjct 2836 LANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAY 2895
Query 119 NGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLE 178
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL
Sbjct 2896 GGTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLM 2955
Query 179 GNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGD-------RWFLNRFTTTLNDFN 231
G FYG +VD + AQ D +T N++AWLYAA+I+ +W L T +++D+N
Sbjct 2956 GEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSLPKW-LESTTVSVDDYN 3014
Query 232 LVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL--QNGMNGRTILGSALLED 289
A + P + + LSA TG+ D+C L+ ++ + G ILG ED
Sbjct 3015 KWAGDNGFTPFSTSTA--ITKLSAITGV---DVCKLLRTIMVKNSQWGGDPILGQYNFED 3069
Query 290 EFTPFDVVRQCSGVTFQ 306
E TP V Q GV Q
Sbjct 3070 ELTPESVFNQIGGVRLQ 3086
>sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=1a PE=1 SV=1
Length=3951
Score = 228 bits (581), Expect = 3e-66, Method: Compositional matrix adjust.
Identities = 131/317 (41%), Positives = 179/317 (56%), Gaps = 21/317 (7%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLI 59
SGF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ S D N D+L
Sbjct 2780 SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIYCPRHVLGKFSGDQWN----DVLN 2835
Query 60 RKSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACY 118
+NH F V + V L V+ ++ VL L+ AN +TPKYKF++ G +F++ Y
Sbjct 2836 LANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAY 2895
Query 119 NGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLE 178
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL
Sbjct 2896 GGTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLM 2955
Query 179 GNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGD-------RWFLNRFTTTLNDFN 231
G FYG +VD + AQ D +T N++AWLYAA+I+ +W L T +++D+N
Sbjct 2956 GEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSLPKW-LESTTVSVDDYN 3014
Query 232 LVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL--QNGMNGRTILGSALLED 289
A + P + + LSA TG+ D+C L+ ++ + G ILG ED
Sbjct 3015 KWAGDNGFTPFSTSTA--ITKLSAITGV---DVCKLLRTIMVKNSQWGGDPILGQYNFED 3069
Query 290 EFTPFDVVRQCSGVTFQ 306
E TP V Q GV Q
Sbjct 3070 ELTPESVFNQIGGVRLQ 3086
>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep
PE=3 SV=1
Length=6629
Score = 227 bits (579), Expect = 5e-66, Method: Compositional matrix adjust.
Identities = 131/317 (41%), Positives = 179/317 (56%), Gaps = 21/317 (7%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLI 59
SGF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ S D N D+L
Sbjct 2780 SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIYCPRHVLGKFSGDQWN----DVLN 2835
Query 60 RKSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACY 118
+NH F V + V L V+ ++ VL L+ AN +TPKYKF++ G +F++ Y
Sbjct 2836 LANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAY 2895
Query 119 NGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLE 178
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL
Sbjct 2896 GGTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLM 2955
Query 179 GNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGD-------RWFLNRFTTTLNDFN 231
G FYG +VD + AQ D +T N++AWLYAA+I+ +W L T +++D+N
Sbjct 2956 GEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSLPKW-LESTTVSVDDYN 3014
Query 232 LVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL--QNGMNGRTILGSALLED 289
A + P + + LSA TG+ D+C L+ ++ + G ILG ED
Sbjct 3015 KWAGDNGFTPFSTSTA--ITKLSAITGV---DVCKLLRTIMVKNSQWGGDPILGQYNFED 3069
Query 290 EFTPFDVVRQCSGVTFQ 306
E TP V Q GV Q
Sbjct 3070 ELTPESVFNQIGGVRLQ 3086
>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1
SV=1
Length=6629
Score = 227 bits (579), Expect = 5e-66, Method: Compositional matrix adjust.
Identities = 131/317 (41%), Positives = 179/317 (56%), Gaps = 21/317 (7%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLI 59
SGF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ S D N D+L
Sbjct 2780 SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIYCPRHVLGKFSGDQWN----DVLN 2835
Query 60 RKSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACY 118
+NH F V + V L V+ ++ VL L+ AN +TPKYKF++ G +F++ Y
Sbjct 2836 LANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAY 2895
Query 119 NGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLE 178
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL
Sbjct 2896 GGTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLM 2955
Query 179 GNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGD-------RWFLNRFTTTLNDFN 231
G FYG +VD + AQ D +T N++AWLYAA+I+ +W L T +++D+N
Sbjct 2956 GEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSLPKW-LESTTVSVDDYN 3014
Query 232 LVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL--QNGMNGRTILGSALLED 289
A + P + + LSA TG+ D+C L+ ++ + G ILG ED
Sbjct 3015 KWAGDNGFTPFSTSTA--ITKLSAITGV---DVCKLLRTIMVKNSQWGGDPILGQYNFED 3069
Query 290 EFTPFDVVRQCSGVTFQ 306
E TP V Q GV Q
Sbjct 3070 ELTPESVFNQIGGVRLQ 3086
>sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=1a PE=1 SV=1
Length=3953
Score = 225 bits (574), Expect = 3e-65, Method: Compositional matrix adjust.
Identities = 128/316 (41%), Positives = 175/316 (55%), Gaps = 19/316 (6%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+GF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ + D+L
Sbjct 2782 AGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVL---GKFSGDQWGDVLNL 2838
Query 61 KSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
+NH F V N V L V+ ++ VL L+ AN +TPKYKFV+ G +F++ Y
Sbjct 2839 ANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYG 2898
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G
Sbjct 2899 GTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMG 2958
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGD-------RWFLNRFTTTLNDFNL 232
FYG +VD + AQ D +T N++AWLYAA+I+ +W L T ++ D+N
Sbjct 2959 EFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKW-LESTTVSIEDYNR 3017
Query 233 VAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRT--ILGSALLEDE 290
A + P + + LSA TG+ D+C L+ ++ + ILG EDE
Sbjct 3018 WASDNGFTPFSTSTA--ITKLSAITGV---DVCKLLRTIMVKSAQWGSDPILGQYNFEDE 3072
Query 291 FTPFDVVRQCSGVTFQ 306
TP V Q GV Q
Sbjct 3073 LTPESVFNQVGGVRLQ 3088
>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631
Score = 224 bits (572), Expect = 5e-65, Method: Compositional matrix adjust.
Identities = 128/316 (41%), Positives = 174/316 (55%), Gaps = 19/316 (6%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+GF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ + D+L
Sbjct 2782 AGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVL---GKFSGDQWGDVLNL 2838
Query 61 KSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
+NH F V N V L V+ ++ VL L+ AN +TPKYKFV+ G +F++ Y
Sbjct 2839 ANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYG 2898
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G
Sbjct 2899 GTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMG 2958
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVI-------NGDRWFLNRFTTTLNDFNL 232
FYG +VD + AQ D +T N++AWLYAA+I + +W L T ++ D+N
Sbjct 2959 EFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKW-LESTTVSIEDYNR 3017
Query 233 VAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN--GRTILGSALLEDE 290
A + P + + LSA TG+ D+C L+ ++ ILG EDE
Sbjct 3018 WASDNGFTPFSTSTA--ITKLSAITGV---DVCKLLRTIMVKSAQWGSDPILGQYNFEDE 3072
Query 291 FTPFDVVRQCSGVTFQ 306
TP V Q GV Q
Sbjct 3073 LTPESVFNQVGGVRLQ 3088
>sp|Q8E919|FIEF_SHEON Cation-efflux pump FieF OS=Shewanella oneidensis
(strain MR-1) OX=211586 GN=fieF PE=1 SV=1
Length=296
Score = 33.5 bits (75), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 21/68 (31%), Positives = 31/68 (46%), Gaps = 3/68 (4%)
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLND-FNLVAMKYN 238
+F+ R A A T IT+ +LAWLY+ + + F TL N +A++Y
Sbjct 8 DFWVKLASR--ASVATALTLITIKLLAWLYSGSASMLASLTDSFADTLASIINFIAIRYA 65
Query 239 YEPLTQDH 246
P DH
Sbjct 66 IVPADHDH 73
>sp|Q6AE15|HIS4_LEIXX 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]
imidazole-4-carboxamide isomerase OS=Leifsonia
xyli subsp. xyli (strain CTCB07) OX=281090 GN=hisA
PE=3 SV=1
Length=248
Score = 33.1 bits (74), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 19/41 (46%), Positives = 25/41 (61%), Gaps = 1/41 (2%)
Query 252 PLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFT 292
P+ A GIA LD A+L+EL+ G+ G I+G AL FT
Sbjct 199 PVVASGGIASLDDIAALRELVSLGVEG-AIVGKALYSGAFT 238
Lambda K H a alpha
0.323 0.138 0.433 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 26429457978
Results from round 2
Query= YP_009725301.1 3C-like proteinase [Severe acute respiratory syndrome
coronavirus 2]
Length=306
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus... 485 5e-156
sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus 2... 485 8e-156
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re... 485 1e-155
sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute resp... 484 2e-155
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res... 484 3e-155
sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respi... 483 5e-155
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus... 482 1e-154
sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus H... 481 2e-154
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus... 480 3e-154
sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus R... 480 5e-154
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir... 470 9e-151
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi... 470 1e-150
sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus... 470 2e-150
sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronaviru... 469 3e-150
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir... 469 4e-150
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi... 469 4e-150
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi... 469 4e-150
sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronaviru... 469 5e-150
sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronaviru... 469 5e-150
sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus... 469 5e-150
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir... 468 9e-150
sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus... 467 1e-149
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res... 465 5e-149
sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respi... 465 6e-149
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi... 465 7e-149
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir... 464 1e-148
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus... 464 2e-148
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus... 464 2e-148
sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronaviru... 464 2e-148
sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus... 464 2e-148
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir... 464 2e-148
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir... 464 2e-148
sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus... 463 3e-148
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus... 463 3e-148
sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus H... 463 3e-148
sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus... 463 4e-148
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir... 463 4e-148
sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus H... 463 5e-148
sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus... 462 6e-148
sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus 1... 462 7e-148
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi... 456 9e-146
sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic ... 455 2e-145
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus... 455 2e-145
sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus H... 455 2e-145
sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus 5... 455 2e-145
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus... 455 3e-145
sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmiss... 454 4e-145
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi... 454 4e-145
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir... 452 2e-144
sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus... 448 8e-143
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir... 447 1e-142
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir... 443 4e-141
sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus... 442 6e-141
sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious ... 398 1e-125
sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious b... 398 1e-125
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou... 397 5e-125
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious... 396 5e-125
sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious b... 393 9e-124
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious... 392 3e-123
Sequences not found previously or not previously below threshold:
sp|G3XP90|CTPE_ASPNA Mitochondrial citrate transporter E OS=Asper... 32.2 6.1
>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079
Score = 485 bits (1250), Expect = 5e-156, Method: Composition-based stats.
Identities = 294/306 (96%), Positives = 303/306 (99%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIR
Sbjct 3247 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3307 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN+TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3367 SPSGVYQCAMRPNYTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3427 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3487 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3546
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3547 SGVTFQ 3552
>sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus
279/2005 OX=389167 GN=1a PE=3 SV=1
Length=4388
Score = 485 bits (1249), Expect = 8e-156, Method: Composition-based stats.
Identities = 294/306 (96%), Positives = 303/306 (99%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIR
Sbjct 3247 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3307 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN+TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3367 SPSGVYQCAMRPNYTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3427 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3487 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3546
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3547 SGVTFQ 3552
>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1
SV=1
Length=7096
Score = 485 bits (1248), Expect = 1e-155, Method: Composition-based stats.
Identities = 306/306 (100%), Positives = 306/306 (100%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR
Sbjct 3264 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 3323
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3324 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 3383
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN
Sbjct 3384 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 3443
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3444 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3503
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC
Sbjct 3504 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 3563
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3564 SGVTFQ 3569
>sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 PE=1 SV=1
Length=4405
Score = 484 bits (1246), Expect = 2e-155, Method: Composition-based stats.
Identities = 306/306 (100%), Positives = 306/306 (100%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR
Sbjct 3264 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 3323
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3324 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 3383
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN
Sbjct 3384 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 3443
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3444 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3503
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC
Sbjct 3504 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 3563
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3564 SGVTFQ 3569
>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score = 484 bits (1245), Expect = 3e-155, Method: Composition-based stats.
Identities = 294/306 (96%), Positives = 302/306 (99%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIR
Sbjct 3241 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3300
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3301 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3541 SGVTFQ 3546
>sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respiratory
syndrome coronavirus OX=694009 GN=1a PE=1 SV=1
Length=4382
Score = 483 bits (1243), Expect = 5e-155, Method: Composition-based stats.
Identities = 294/306 (96%), Positives = 302/306 (99%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIR
Sbjct 3241 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3300
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3301 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3541 SGVTFQ 3546
>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067
Score = 482 bits (1241), Expect = 1e-154, Method: Composition-based stats.
Identities = 292/306 (95%), Positives = 302/306 (99%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHV+CT+EDMLNPNY+DLLIR
Sbjct 3235 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVVCTAEDMLNPNYDDLLIR 3294
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3295 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3354
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3355 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3414
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3415 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3474
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3475 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3534
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3535 SGVTFQ 3540
>sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus
HKU3 OX=442736 GN=1a PE=3 SV=1
Length=4376
Score = 481 bits (1238), Expect = 2e-154, Method: Composition-based stats.
Identities = 292/306 (95%), Positives = 302/306 (99%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHV+CT+EDMLNPNY+DLLIR
Sbjct 3235 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVVCTAEDMLNPNYDDLLIR 3294
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3295 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3354
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3355 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3414
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3415 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3474
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3475 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3534
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3535 SGVTFQ 3540
>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071
Score = 480 bits (1237), Expect = 3e-154, Method: Composition-based stats.
Identities = 293/306 (96%), Positives = 301/306 (98%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIR
Sbjct 3239 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3298
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3299 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3358
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT VHAGTDLEG
Sbjct 3359 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTEVHAGTDLEGK 3418
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3419 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3478
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3479 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3538
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3539 SGVTFQ 3544
>sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus
Rp3/2004 OX=349344 GN=1a PE=3 SV=1
Length=4380
Score = 480 bits (1236), Expect = 5e-154, Method: Composition-based stats.
Identities = 293/306 (96%), Positives = 301/306 (98%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIR
Sbjct 3239 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3298
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
KSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3299 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3358
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
SPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT VHAGTDLEG
Sbjct 3359 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTEVHAGTDLEGK 3418
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3419 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3478
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
PLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQC
Sbjct 3479 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3538
Query 301 SGVTFQ 306
SGVTFQ
Sbjct 3539 SGVTFQ 3544
>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124
Score = 470 bits (1211), Expect = 9e-151, Method: Composition-based stats.
Identities = 155/306 (51%), Positives = 200/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM FP+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R
Sbjct 3280 SGIVKMVFPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYSNLLCR 3339
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F V +G + L V+ + MQ +L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3340 VISSDFCVMSGRMSLTVMSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNG 3399
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3400 KSQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGN 3459
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D T TVNV+AWLYAA++N WF+ + +L +FN+ AM +
Sbjct 3460 FYGPYRDAQVVQLPVQDYTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFS 3519
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q
Sbjct 3520 SIKADLV--LDALASMTGVTVEQILAAIKRLY-SGFQGKQILGSCVLEDELTPSDVYQQL 3576
Query 301 SGVTFQ 306
+GV Q
Sbjct 3577 AGVKLQ 3582
>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180
Score = 470 bits (1210), Expect = 1e-150, Method: Composition-based stats.
Identities = 154/306 (50%), Positives = 199/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R
Sbjct 3337 SGIVKMVSPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCR 3396
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + + L V+ + MQ +L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3397 VTSSDFCVMSDRMSLTVMSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNG 3456
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR + TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3457 RPQGAFHVVMRSSHTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGN 3516
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D T TVNV+AWLYAA++N WF+ + +L +FN+ AM +
Sbjct 3517 FYGPYRDAQVVQLPVQDYTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFS 3576
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q
Sbjct 3577 SIKADLV--LDALASMTGVTVEQVLAAIKR-LHSGFQGKQILGSCVLEDELTPSDVYQQL 3633
Query 301 SGVTFQ 306
+GV Q
Sbjct 3634 AGVKLQ 3639
>sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus
(strain 2) OX=76344 GN=1a PE=3 SV=1
Length=4416
Score = 470 bits (1209), Expect = 2e-150, Method: Composition-based stats.
Identities = 155/306 (51%), Positives = 200/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM FP+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R
Sbjct 3280 SGIVKMVFPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYSNLLCR 3339
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F V +G + L V+ + MQ +L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3340 VISSDFCVMSGRMSLTVMSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNG 3399
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3400 KSQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGN 3459
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D T TVNV+AWLYAA++N WF+ + +L +FN+ AM +
Sbjct 3460 FYGPYRDAQVVQLPVQDYTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFS 3519
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q
Sbjct 3520 SIKADLV--LDALASMTGVTVEQILAAIKRLY-SGFQGKQILGSCVLEDELTPSDVYQQL 3576
Query 301 SGVTFQ 306
+GV Q
Sbjct 3577 AGVKLQ 3582
>sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronavirus
(strain JHM) OX=11144 GN=1a PE=1 SV=1
Length=4474
Score = 469 bits (1208), Expect = 3e-150, Method: Composition-based stats.
Identities = 154/306 (50%), Positives = 199/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R
Sbjct 3337 SGIVKMVSPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCR 3396
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + + L V+ + MQ +L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3397 VTSSDFCVMSDRMSLTVMSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNG 3456
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR + TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3457 RPQGAFHVVMRSSHTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGN 3516
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D T TVNV+AWLYAA++N WF+ + +L +FN+ AM +
Sbjct 3517 FYGPYRDAQVVQLPVQDYTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFS 3576
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q
Sbjct 3577 SIKADLV--LDALASMTGVTVEQVLAAIKR-LHSGFQGKQILGSCVLEDELTPSDVYQQL 3633
Query 301 SGVTFQ 306
+GV Q
Sbjct 3634 AGVKLQ 3639
>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059
Score = 469 bits (1207), Expect = 4e-150, Method: Composition-based stats.
Identities = 148/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094
Score = 469 bits (1207), Expect = 4e-150, Method: Composition-based stats.
Identities = 147/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094
Score = 469 bits (1207), Expect = 4e-150, Method: Composition-based stats.
Identities = 147/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=1a PE=3 SV=1
Length=4383
Score = 469 bits (1206), Expect = 5e-150, Method: Composition-based stats.
Identities = 147/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=1a PE=3 SV=1
Length=4383
Score = 469 bits (1206), Expect = 5e-150, Method: Composition-based stats.
Identities = 147/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=1a PE=3 SV=1
Length=4383
Score = 469 bits (1206), Expect = 5e-150, Method: Composition-based stats.
Identities = 148/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095
Score = 468 bits (1204), Expect = 9e-150, Method: Composition-based stats.
Identities = 148/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + M+ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMRGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN LAWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPIQDYIQSVNFLAWLYAAILNNCNWFIQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus
OC43 OX=31631 GN=1a PE=1 SV=1
Length=4383
Score = 467 bits (1203), Expect = 1e-149, Method: Composition-based stats.
Identities = 148/306 (48%), Positives = 198/306 (65%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + M+ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMRGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN LAWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPIQDYIQSVNFLAWLYAAILNNCNWFIQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=rep PE=1 SV=1
Length=7078
Score = 465 bits (1198), Expect = 5e-149, Method: Composition-based stats.
Identities = 156/310 (50%), Positives = 206/310 (66%), Gaps = 8/310 (3%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM+ PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+ LLI
Sbjct 3248 SGLVKMSHPSGDVEACMVQVTCGSMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLIS 3307
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
+NH+F VQ LRV+GH+MQ +LKL VD ANP TP Y F ++PG FSVLAC
Sbjct 3308 MTNHSFSVQKHIGAPANLRVVGHAMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLAC 3367
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+G + MRPN+TIKGSFL GSCGSVG+ + ++FCYMH MEL G H G+
Sbjct 3368 YNGRPTGTFTVVMRPNYTIKGSFLCGSCGSVGYTKEGSVINFCYMHQMELANGTHTGSAF 3427
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F+D+Q Q TD +VNV+AWLYAA++NG WF+ T++ FN A+
Sbjct 3428 DGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALAN 3487
Query 238 NYE-PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDV 296
+ + VD+ L+ +TG+A+ + ++++L G G+ ILGS +LEDEFTP DV
Sbjct 3488 QFTEFVGTQSVDM---LAVKTGVAIEQLLYAIQQLY-TGFQGKQILGSTMLEDEFTPEDV 3543
Query 297 VRQCSGVTFQ 306
Q GV Q
Sbjct 3544 NMQIMGVVMQ 3553
>sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respiratory
syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=1a PE=1 SV=1
Length=4391
Score = 465 bits (1198), Expect = 6e-149, Method: Composition-based stats.
Identities = 156/310 (50%), Positives = 206/310 (66%), Gaps = 8/310 (3%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM+ PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+ LLI
Sbjct 3248 SGLVKMSHPSGDVEACMVQVTCGSMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLIS 3307
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
+NH+F VQ LRV+GH+MQ +LKL VD ANP TP Y F ++PG FSVLAC
Sbjct 3308 MTNHSFSVQKHIGAPANLRVVGHAMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLAC 3367
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+G + MRPN+TIKGSFL GSCGSVG+ + ++FCYMH MEL G H G+
Sbjct 3368 YNGRPTGTFTVVMRPNYTIKGSFLCGSCGSVGYTKEGSVINFCYMHQMELANGTHTGSAF 3427
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F+D+Q Q TD +VNV+AWLYAA++NG WF+ T++ FN A+
Sbjct 3428 DGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALAN 3487
Query 238 NYE-PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDV 296
+ + VD+ L+ +TG+A+ + ++++L G G+ ILGS +LEDEFTP DV
Sbjct 3488 QFTEFVGTQSVDM---LAVKTGVAIEQLLYAIQQLY-TGFQGKQILGSTMLEDEFTPEDV 3543
Query 297 VRQCSGVTFQ 306
Q GV Q
Sbjct 3544 NMQIMGVVMQ 3553
>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176
Score = 465 bits (1197), Expect = 7e-149, Method: Composition-based stats.
Identities = 155/306 (51%), Positives = 199/306 (65%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R
Sbjct 3334 SGIVKMVSPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCR 3393
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3394 VTSSDFCVMSGRMSLTVMSYQMQGCQLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNG 3453
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + +R + TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3454 RPQGAFHVTLRSSHTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGN 3513
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D T TVNV+AWLYAA+ N WF+ + +L +FN+ AM +
Sbjct 3514 FYGPYRDAQVVQLPVQDYTQTVNVVAWLYAAIFNRCNWFVQSDSCSLEEFNVWAMTNGFS 3573
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q
Sbjct 3574 SIKADLV--LDALASMTGVTVEQVLAAIKR-LHSGFQGKQILGSCVLEDE-TPSDVYQQL 3629
Query 301 SGVTFQ 306
+GV Q
Sbjct 3630 AGVKLQ 3635
>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094
Score = 464 bits (1195), Expect = 1e-148, Method: Composition-based stats.
Identities = 146/306 (48%), Positives = 196/306 (64%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWL D VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLGDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSV + I DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVVYVIMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKH-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119
Score = 464 bits (1194), Expect = 2e-148, Method: Composition-based stats.
Identities = 152/309 (49%), Positives = 201/309 (65%), Gaps = 6/309 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM+ PSG VE C+VQVTCG+ TLNGLWLD+ V+CPRH++C ++ + +PNY+ LLI
Sbjct 3292 SGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLIS 3351
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
K+NH+F+VQ LRV+ HSM +LKL VD ANP TP Y F ++PG +FSVLAC
Sbjct 3352 KTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLAC 3411
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+GV+ +R N TIKGSFL GSCGSVG+ + ++F YMH MEL G H G+
Sbjct 3412 YNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSF 3471
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F D+QT Q TD T+NV+AWLYAAV+NG +WF+ + +N A+
Sbjct 3472 DGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSN 3531
Query 238 NYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVV 297
+ + L+ +TG++V M A+++ L G G+TILG + LEDEFTP DV
Sbjct 3532 QFTEFVG--TQSIDMLAHRTGVSVEQMLAAIQS-LHAGFQGKTILGQSTLEDEFTPDDVN 3588
Query 298 RQCSGVTFQ 306
Q GV Q
Sbjct 3589 MQVMGVVMQ 3597
>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182
Score = 464 bits (1194), Expect = 2e-148, Method: Composition-based stats.
Identities = 154/310 (50%), Positives = 207/310 (67%), Gaps = 8/310 (3%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KMA PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+ LL+
Sbjct 3339 SGLVKMAAPSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDALLVS 3398
Query 61 KSNHNFLVQAG---NVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
K+N +F+VQ LRV+GH+M +LKL V++ANP+TP Y F ++PG +FSVLAC
Sbjct 3399 KTNLSFIVQKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFSVLAC 3458
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+GV+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H G
Sbjct 3459 YNGRPTGVFMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHTGCAF 3518
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F DRQ Q +D T+N++AWLYAA++NG WF+ T + FN AM
Sbjct 3519 DGVMYGAFEDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEWAMSN 3578
Query 238 NYE-PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDV 296
+ + VD+ L+ +TG++V + +++ L G G+TILG+++LEDEFTP DV
Sbjct 3579 QFTEFIGTQSVDM---LAHKTGVSVEQLLYAIQT-LHKGFQGKTILGNSMLEDEFTPDDV 3634
Query 297 VRQCSGVTFQ 306
Q GV Q
Sbjct 3635 NMQVMGVVMQ 3644
>sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronavirus
(strain A59) OX=11142 GN=1a PE=1 SV=1
Length=4468
Score = 464 bits (1194), Expect = 2e-148, Method: Composition-based stats.
Identities = 155/306 (51%), Positives = 199/306 (65%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R
Sbjct 3334 SGIVKMVSPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCR 3393
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3394 VTSSDFCVMSGRMSLTVMSYQMQGCQLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNG 3453
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + +R + TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3454 RPQGAFHVTLRSSHTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGN 3513
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D T TVNV+AWLYAA+ N WF+ + +L +FN+ AM +
Sbjct 3514 FYGPYRDAQVVQLPVQDYTQTVNVVAWLYAAIFNRCNWFVQSDSCSLEEFNVWAMTNGFS 3573
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q
Sbjct 3574 SIKADLV--LDALASMTGVTVEQVLAAIKR-LHSGFQGKQILGSCVLEDE-TPSDVYQQL 3629
Query 301 SGVTFQ 306
+GV Q
Sbjct 3630 AGVKLQ 3635
>sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=1a PE=3 SV=1
Length=4383
Score = 464 bits (1194), Expect = 2e-148, Method: Composition-based stats.
Identities = 146/306 (48%), Positives = 196/306 (64%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ KVE C+V VT G TLNGLWL D VYCPRHVIC++ DM NP+Y +LL R
Sbjct 3247 SGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLGDKVYCPRHVICSASDMTNPDYTNLLCR 3306
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
++ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3307 VTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNG 3366
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSV + I DCV F YMH +EL TG H GTD G+
Sbjct 3367 KPQGAFHVTMRSSYTIKGSFLCGSCGSVVYVIMGDCVKFVYMHQLELSTGCHTGTDFNGD 3426
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3427 FYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFS 3486
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q
Sbjct 3487 QVKSDLV--IDALASMTGVSLETLLAAIKH-LKNGFQGRQIMGSCSFEDELTPSDVYQQL 3543
Query 301 SGVTFQ 306
+G+ Q
Sbjct 3544 AGIKLQ 3549
>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152
Score = 464 bits (1194), Expect = 2e-148, Method: Composition-based stats.
Identities = 150/306 (49%), Positives = 193/306 (63%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R
Sbjct 3305 SGIVKMVSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCR 3364
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F + +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3365 VTLGDFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNG 3424
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3425 RPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGN 3484
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM +
Sbjct 3485 FYGPYRDAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFS 3544
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q
Sbjct 3545 QVKADLV--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQL 3601
Query 301 SGVTFQ 306
+GV Q
Sbjct 3602 AGVKLQ 3607
>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132
Score = 464 bits (1194), Expect = 2e-148, Method: Composition-based stats.
Identities = 150/306 (49%), Positives = 193/306 (63%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R
Sbjct 3285 SGIVKMVSPTSKIEPCLVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCR 3344
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F + +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3345 VTLGDFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNG 3404
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3405 RPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFNGN 3464
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM +
Sbjct 3465 FYGPYRDAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFS 3524
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q
Sbjct 3525 QVKADLV--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQL 3581
Query 301 SGVTFQ 306
+GV Q
Sbjct 3582 AGVKLQ 3587
>sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=1a PE=3 SV=1
Length=4441
Score = 463 bits (1192), Expect = 3e-148, Method: Composition-based stats.
Identities = 150/306 (49%), Positives = 193/306 (63%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R
Sbjct 3305 SGIVKMVSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCR 3364
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F + +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3365 VTLGDFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNG 3424
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3425 RPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGN 3484
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM +
Sbjct 3485 FYGPYRDAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFS 3544
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q
Sbjct 3545 QVKADLV--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQL 3601
Query 301 SGVTFQ 306
+GV Q
Sbjct 3602 AGVKLQ 3607
>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126
Score = 463 bits (1192), Expect = 3e-148, Method: Composition-based stats.
Identities = 152/309 (49%), Positives = 201/309 (65%), Gaps = 6/309 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM+ PSG VE C+VQVTCG+ TLNGLWLD+ V+CPRH++C ++ + +PNY+ LLI
Sbjct 3299 SGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLIS 3358
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
K+NH+F+VQ LRV+ HSM +LKL VD ANP TP Y F ++PG +FSVLAC
Sbjct 3359 KTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLAC 3418
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+GV+ +R N TIKGSFL GSCGSVG+ + ++F YMH MEL G H G+
Sbjct 3419 YNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVLNFVYMHQMELSNGTHTGSSF 3478
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F D+QT Q TD T+NV+AWLYAAV+NG +WF+ + +N A+
Sbjct 3479 DGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSN 3538
Query 238 NYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVV 297
+ + L+ +TG++V M A+++ L G G+TILG + LEDEFTP DV
Sbjct 3539 QFTEFVG--TQSIDMLAHRTGVSVEQMLAAIQS-LHAGFQGKTILGQSTLEDEFTPDDVN 3595
Query 298 RQCSGVTFQ 306
Q GV Q
Sbjct 3596 MQVMGVVMQ 3604
>sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus
HKU4 OX=694007 GN=1a PE=1 SV=1
Length=4434
Score = 463 bits (1192), Expect = 3e-148, Method: Composition-based stats.
Identities = 152/309 (49%), Positives = 201/309 (65%), Gaps = 6/309 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM+ PSG VE C+VQVTCG+ TLNGLWLD+ V+CPRH++C ++ + +PNY+ LLI
Sbjct 3292 SGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLIS 3351
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
K+NH+F+VQ LRV+ HSM +LKL VD ANP TP Y F ++PG +FSVLAC
Sbjct 3352 KTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLAC 3411
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+GV+ +R N TIKGSFL GSCGSVG+ + ++F YMH MEL G H G+
Sbjct 3412 YNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSF 3471
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F D+QT Q TD T+NV+AWLYAAV+NG +WF+ + +N A+
Sbjct 3472 DGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSN 3531
Query 238 NYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVV 297
+ + L+ +TG++V M A+++ L G G+TILG + LEDEFTP DV
Sbjct 3532 QFTEFVG--TQSIDMLAHRTGVSVEQMLAAIQS-LHAGFQGKTILGQSTLEDEFTPDDVN 3588
Query 298 RQCSGVTFQ 306
Q GV Q
Sbjct 3589 MQVMGVVMQ 3597
>sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=1a PE=3 SV=1
Length=4421
Score = 463 bits (1192), Expect = 4e-148, Method: Composition-based stats.
Identities = 150/306 (49%), Positives = 193/306 (63%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R
Sbjct 3285 SGIVKMVSPTSKIEPCLVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCR 3344
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F + +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3345 VTLGDFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNG 3404
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3405 RPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFNGN 3464
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM +
Sbjct 3465 FYGPYRDAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFS 3524
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q
Sbjct 3525 QVKADLV--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQL 3581
Query 301 SGVTFQ 306
+GV Q
Sbjct 3582 AGVKLQ 3587
>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182
Score = 463 bits (1192), Expect = 4e-148, Method: Composition-based stats.
Identities = 150/306 (49%), Positives = 193/306 (63%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC+S +M P+Y LL R
Sbjct 3335 SGIVKMVSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICSSSNMNEPDYSALLCR 3394
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F + +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3395 VTLGDFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGNVKPGETFTVLAAYNG 3454
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3455 RPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGN 3514
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D TVNV+AWLYAA++N WF+ + DFN+ AM +
Sbjct 3515 FYGPYRDAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSTEDFNVWAMANGFS 3574
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q
Sbjct 3575 QVKADLV--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQL 3631
Query 301 SGVTFQ 306
+GV Q
Sbjct 3632 AGVKLQ 3637
>sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus
HKU5 OX=694008 GN=1a PE=3 SV=1
Length=4481
Score = 463 bits (1191), Expect = 5e-148, Method: Composition-based stats.
Identities = 154/310 (50%), Positives = 207/310 (67%), Gaps = 8/310 (3%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KMA PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+ LL+
Sbjct 3339 SGLVKMAAPSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDALLVS 3398
Query 61 KSNHNFLVQAG---NVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
K+N +F+VQ LRV+GH+M +LKL V++ANP+TP Y F ++PG +FSVLAC
Sbjct 3399 KTNLSFIVQKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFSVLAC 3458
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+GV+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H G
Sbjct 3459 YNGRPTGVFMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHTGCAF 3518
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F DRQ Q +D T+N++AWLYAA++NG WF+ T + FN AM
Sbjct 3519 DGVMYGAFEDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEWAMSN 3578
Query 238 NYE-PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDV 296
+ + VD+ L+ +TG++V + +++ L G G+TILG+++LEDEFTP DV
Sbjct 3579 QFTEFIGTQSVDM---LAHKTGVSVEQLLYAIQT-LHKGFQGKTILGNSMLEDEFTPDDV 3634
Query 297 VRQCSGVTFQ 306
Q GV Q
Sbjct 3635 NMQVMGVVMQ 3644
>sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=1a PE=1 SV=1
Length=4471
Score = 462 bits (1190), Expect = 6e-148, Method: Composition-based stats.
Identities = 150/306 (49%), Positives = 193/306 (63%), Gaps = 3/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC+S +M P+Y LL R
Sbjct 3335 SGIVKMVSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICSSSNMNEPDYSALLCR 3394
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+ +F + +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG
Sbjct 3395 VTLGDFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGNVKPGETFTVLAAYNG 3454
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P G + MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GN
Sbjct 3455 RPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGN 3514
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGP+ D Q Q D TVNV+AWLYAA++N WF+ + DFN+ AM +
Sbjct 3515 FYGPYRDAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSTEDFNVWAMANGFS 3574
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q
Sbjct 3575 QVKADLV--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQL 3631
Query 301 SGVTFQ 306
+GV Q
Sbjct 3632 AGVKLQ 3637
>sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus
133/2005 OX=389230 GN=1a PE=3 SV=1
Length=4441
Score = 462 bits (1190), Expect = 7e-148, Method: Composition-based stats.
Identities = 152/309 (49%), Positives = 201/309 (65%), Gaps = 6/309 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG KM+ PSG VE C+VQVTCG+ TLNGLWLD+ V+CPRH++C ++ + +PNY+ LLI
Sbjct 3299 SGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLIS 3358
Query 61 KSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 117
K+NH+F+VQ LRV+ HSM +LKL VD ANP TP Y F ++PG +FSVLAC
Sbjct 3359 KTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLAC 3418
Query 118 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 177
YNG P+GV+ +R N TIKGSFL GSCGSVG+ + ++F YMH MEL G H G+
Sbjct 3419 YNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVLNFVYMHQMELSNGTHTGSSF 3478
Query 178 EGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 237
+G YG F D+QT Q TD T+NV+AWLYAAV+NG +WF+ + +N A+
Sbjct 3479 DGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSN 3538
Query 238 NYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVV 297
+ + L+ +TG++V M A+++ L G G+TILG + LEDEFTP DV
Sbjct 3539 QFTEFVG--TQSIDMLAHRTGVSVEQMLAAIQS-LHAGFQGKTILGQSTLEDEFTPDDVN 3595
Query 298 RQCSGVTFQ 306
Q GV Q
Sbjct 3596 MQVMGVVMQ 3604
>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781
Score = 456 bits (1174), Expect = 9e-146, Method: Composition-based stats.
Identities = 137/306 (45%), Positives = 195/306 (64%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+G RKMA PSG VE C+V+V G LNGLWL D+V CPRHVI +S +Y+ L
Sbjct 2998 AGLRKMAQPSGVVEKCIVRVCYGNMALNGLWLGDIVMCPRHVIASSTTST-IDYDYALSV 3056
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF + +GNV L V+ +M+ +L++KV+ N TPKY + ++PG++F++LACY+G
Sbjct 3057 LRLHNFSISSGNVFLGVVSATMRGALLQIKVNQNNVHTPKYTYRTVRPGESFNILACYDG 3116
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
+ +GVY MR N+TI+GSF+NG+CGS G+NI+ V FCY+H +EL +G H G+DL+G
Sbjct 3117 AAAGVYGVNMRSNYTIRGSFINGACGSPGYNINNGTVEFCYLHQLELGSGCHVGSDLDGV 3176
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
YG + D+ T Q G + T NVLA+LYAA+ING W+L+ ++ FN A+
Sbjct 3177 MYGGYEDQPTLQVEGASSLFTENVLAFLYAALINGSTWWLSSSRIAVDRFNEWAVHNGMT 3236
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ + D L+A+TG+ V + AS++ L +N G+ ILG L DEFT +VVRQ
Sbjct 3237 TVG--NTDCFSILAAKTGVDVQRLLASIQSLHKN-FGGKQILGHTSLTDEFTTGEVVRQM 3293
Query 301 SGVTFQ 306
GV Q
Sbjct 3294 YGVNLQ 3299
>sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=1a PE=1 SV=1
Length=4117
Score = 455 bits (1172), Expect = 2e-145, Method: Composition-based stats.
Identities = 137/306 (45%), Positives = 195/306 (64%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+G RKMA PSG VE C+V+V G LNGLWL D+V CPRHVI +S +Y+ L
Sbjct 2998 AGLRKMAQPSGVVEKCIVRVCYGNMALNGLWLGDIVMCPRHVIASSTTST-IDYDYALSV 3056
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF + +GNV L V+ +M+ +L++KV+ N TPKY + ++PG++F++LACY+G
Sbjct 3057 LRLHNFSISSGNVFLGVVSATMRGALLQIKVNQNNVHTPKYTYRTVRPGESFNILACYDG 3116
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
+ +GVY MR N+TI+GSF+NG+CGS G+NI+ V FCY+H +EL +G H G+DL+G
Sbjct 3117 AAAGVYGVNMRSNYTIRGSFINGACGSPGYNINNGTVEFCYLHQLELGSGCHVGSDLDGV 3176
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
YG + D+ T Q G + T NVLA+LYAA+ING W+L+ ++ FN A+
Sbjct 3177 MYGGYEDQPTLQVEGASSLFTENVLAFLYAALINGSTWWLSSSRIAVDRFNEWAVHNGMT 3236
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ + D L+A+TG+ V + AS++ L +N G+ ILG L DEFT +VVRQ
Sbjct 3237 TVG--NTDCFSILAAKTGVDVQRLLASIQSLHKN-FGGKQILGHTSLTDEFTTGEVVRQM 3293
Query 301 SGVTFQ 306
GV Q
Sbjct 3294 YGVNLQ 3299
>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930
Score = 455 bits (1172), Expect = 2e-145, Method: Composition-based stats.
Identities = 159/306 (52%), Positives = 214/306 (70%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+G +MA PSG VE C+V+V G+ TLNG+WLD+ V CPRHV+C+ +++ NP+Y L +R
Sbjct 3104 AGLTRMAHPSGLVEPCLVKVNYGSMTLNGIWLDNFVICPRHVMCSRDELANPDYPRLSMR 3163
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+N++F V +RVIGH+M+ +LKL VD NPKTP Y F+R+ GQ S+LACY+G
Sbjct 3164 AANYDFHVSQNGHNIRVIGHTMEGSLLKLTVDVNNPKTPAYSFIRVSTGQAMSLLACYDG 3223
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P+GVY C +R N T++ SFL GSCGS GF ++ V FCY+H +ELP G H GTD G
Sbjct 3224 LPTGVYTCTLRSNGTMRASFLCGSCGSPGFVMNGKEVQFCYLHQLELPNGTHTGTDFSGV 3283
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPF D+Q Q A D TITVNVLAWLYAAV++G+ WFL + + + +FN A+KY +
Sbjct 3284 FYGPFEDKQVPQLAAPDCTITVNVLAWLYAAVLSGENWFLTKSSISPAEFNNCAVKYMCQ 3343
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+T + + +L PL+A+TGI+V M ++LK LL G GRTI+GS LEDE TP+D+ RQ
Sbjct 3344 SVTSESLQVLQPLAAKTGISVERMLSALKVLLSAGFCGRTIMGSCSLEDEHTPYDIGRQM 3403
Query 301 SGVTFQ 306
GV Q
Sbjct 3404 LGVKLQ 3409
>sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus
HKU9 OX=694006 GN=1a PE=3 SV=1
Length=4248
Score = 455 bits (1172), Expect = 2e-145, Method: Composition-based stats.
Identities = 159/306 (52%), Positives = 214/306 (70%), Gaps = 0/306 (0%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+G +MA PSG VE C+V+V G+ TLNG+WLD+ V CPRHV+C+ +++ NP+Y L +R
Sbjct 3104 AGLTRMAHPSGLVEPCLVKVNYGSMTLNGIWLDNFVICPRHVMCSRDELANPDYPRLSMR 3163
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
+N++F V +RVIGH+M+ +LKL VD NPKTP Y F+R+ GQ S+LACY+G
Sbjct 3164 AANYDFHVSQNGHNIRVIGHTMEGSLLKLTVDVNNPKTPAYSFIRVSTGQAMSLLACYDG 3223
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P+GVY C +R N T++ SFL GSCGS GF ++ V FCY+H +ELP G H GTD G
Sbjct 3224 LPTGVYTCTLRSNGTMRASFLCGSCGSPGFVMNGKEVQFCYLHQLELPNGTHTGTDFSGV 3283
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
FYGPF D+Q Q A D TITVNVLAWLYAAV++G+ WFL + + + +FN A+KY +
Sbjct 3284 FYGPFEDKQVPQLAAPDCTITVNVLAWLYAAVLSGENWFLTKSSISPAEFNNCAVKYMCQ 3343
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+T + + +L PL+A+TGI+V M ++LK LL G GRTI+GS LEDE TP+D+ RQ
Sbjct 3344 SVTSESLQVLQPLAAKTGISVERMLSALKVLLSAGFCGRTIMGSCSLEDEHTPYDIGRQM 3403
Query 301 SGVTFQ 306
GV Q
Sbjct 3404 LGVKLQ 3409
>sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus
512/2005 OX=693999 GN=1a PE=3 SV=1
Length=4128
Score = 455 bits (1171), Expect = 2e-145, Method: Composition-based stats.
Identities = 139/306 (45%), Positives = 200/306 (65%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+G RKMA PSG VEGC+V+V+ G TLNGLWL D V CPRHVI ++ +Y+ +
Sbjct 3013 AGLRKMAQPSGIVEGCIVRVSYGNLTLNGLWLGDTVICPRHVIASNTT-NVIDYDHAMSL 3071
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF + +GN+ L VI SM+ +L +KV+ +N TP Y + ++PG +F++LACY+G
Sbjct 3072 VRLHNFSISSGNMFLGVISASMRGTLLHIKVNQSNVNTPNYTYKVLKPGDSFNILACYDG 3131
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
S +GVY MR N+TI+GSF++G+CGS G+NI+ V FCYMHH+EL +G H G+D++G
Sbjct 3132 SAAGVYGVNMRTNYTIRGSFISGACGSPGYNINNGVVEFCYMHHLELGSGCHVGSDMDGT 3191
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
YG + D+ T Q G +T NV +WLY A+INGDRW+L+ + ++ +N A++
Sbjct 3192 MYGKYEDQPTLQIEGASNLVTENVCSWLYGALINGDRWWLSSVSVGVDTYNEWALRNGMT 3251
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
L +VD L A+TG+ V + AS+++L N G++ILG L DEFT +VV+Q
Sbjct 3252 ALK--NVDCFSLLVAKTGVDVGRLLASIQKLHGN-FGGKSILGCTSLCDEFTLSEVVKQM 3308
Query 301 SGVTFQ 306
GVT Q
Sbjct 3309 YGVTLQ 3314
>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793
Score = 455 bits (1170), Expect = 3e-145, Method: Composition-based stats.
Identities = 139/306 (45%), Positives = 200/306 (65%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+G RKMA PSG VEGC+V+V+ G TLNGLWL D V CPRHVI ++ +Y+ +
Sbjct 3013 AGLRKMAQPSGIVEGCIVRVSYGNLTLNGLWLGDTVICPRHVIASNTT-NVIDYDHAMSL 3071
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF + +GN+ L VI SM+ +L +KV+ +N TP Y + ++PG +F++LACY+G
Sbjct 3072 VRLHNFSISSGNMFLGVISASMRGTLLHIKVNQSNVNTPNYTYKVLKPGDSFNILACYDG 3131
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
S +GVY MR N+TI+GSF++G+CGS G+NI+ V FCYMHH+EL +G H G+D++G
Sbjct 3132 SAAGVYGVNMRTNYTIRGSFISGACGSPGYNINNGVVEFCYMHHLELGSGCHVGSDMDGT 3191
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
YG + D+ T Q G +T NV +WLY A+INGDRW+L+ + ++ +N A++
Sbjct 3192 MYGKYEDQPTLQIEGASNLVTENVCSWLYGALINGDRWWLSSVSVGVDTYNEWALRNGMT 3251
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
L +VD L A+TG+ V + AS+++L N G++ILG L DEFT +VV+Q
Sbjct 3252 ALK--NVDCFSLLVAKTGVDVGRLLASIQKLHGN-FGGKSILGCTSLCDEFTLSEVVKQM 3308
Query 301 SGVTFQ 306
GVT Q
Sbjct 3309 YGVTLQ 3314
>sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=1a PE=1 SV=1
Length=4017
Score = 454 bits (1169), Expect = 4e-145, Method: Composition-based stats.
Identities = 136/306 (44%), Positives = 185/306 (60%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG RKMA PSG VE C+V+V+ G LNGLWL D V CPRHVI + + NYE+ +
Sbjct 2879 SGLRKMAQPSGLVEPCIVRVSYGNNVLNGLWLGDEVICPRHVIASDTTRV-INYENEMSS 2937
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF V NV L V+ + L LKV+ NP TP++KF I+ G++F++LACY G
Sbjct 2938 VRLHNFSVSKNNVFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIKAGESFNILACYEG 2997
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++ EG
Sbjct 2998 CPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLELGNGSHVGSNFEGE 3057
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + +L +N A ++
Sbjct 3058 MYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSLESYNTWAKTNSFT 3117
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
L+ D L+A+TG +V + S+ L G GRTIL L DEFTP +V+RQ
Sbjct 3118 ELSS--TDAFSMLAAKTGQSVEKLLDSIVR-LNKGFGGRTILSYGSLCDEFTPTEVIRQM 3174
Query 301 SGVTFQ 306
GV Q
Sbjct 3175 YGVNLQ 3180
>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=rep PE=1 SV=1
Length=6684
Score = 454 bits (1169), Expect = 4e-145, Method: Composition-based stats.
Identities = 136/306 (44%), Positives = 185/306 (60%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG RKMA PSG VE C+V+V+ G LNGLWL D V CPRHVI + + NYE+ +
Sbjct 2879 SGLRKMAQPSGLVEPCIVRVSYGNNVLNGLWLGDEVICPRHVIASDTTRV-INYENEMSS 2937
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF V NV L V+ + L LKV+ NP TP++KF I+ G++F++LACY G
Sbjct 2938 VRLHNFSVSKNNVFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIKAGESFNILACYEG 2997
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++ EG
Sbjct 2998 CPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLELGNGSHVGSNFEGE 3057
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + +L +N A ++
Sbjct 3058 MYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSLESYNTWAKTNSFT 3117
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
L+ D L+A+TG +V + S+ L G GRTIL L DEFTP +V+RQ
Sbjct 3118 ELSS--TDAFSMLAAKTGQSVEKLLDSIVR-LNKGFGGRTILSYGSLCDEFTPTEVIRQM 3174
Query 301 SGVTFQ 306
GV Q
Sbjct 3175 YGVNLQ 3180
>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709
Score = 452 bits (1164), Expect = 2e-144, Method: Composition-based stats.
Identities = 135/306 (44%), Positives = 183/306 (60%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG RKMA PSG VE C+V+V G LNGLWL D V CPRHVI + + NYE+ L
Sbjct 2904 SGLRKMAQPSGVVEPCIVRVAYGNNVLNGLWLGDEVICPRHVIASDTSRV-INYENELSS 2962
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF + N L V+ + L LKV+ NP TP++KF ++PG++F++LACY G
Sbjct 2963 VRLHNFSIAKNNAFLGVVSAKYKGVNLVLKVNQVNPNTPEHKFKSVRPGESFNILACYEG 3022
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++LEG
Sbjct 3023 CPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGTLYFVYMHHLELGNGSHVGSNLEGE 3082
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + TL +N A ++
Sbjct 3083 MYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMTLESYNAWAKTNSFT 3142
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ D L+A+TG +V + + L G GRTIL L DEFTP +V+RQ
Sbjct 3143 EIVS--TDAFNMLAAKTGYSVEKLLECIVR-LNKGFGGRTILSYGSLCDEFTPTEVIRQM 3199
Query 301 SGVTFQ 306
GV Q
Sbjct 3200 YGVNLQ 3205
>sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus
229E OX=11137 GN=1a PE=1 SV=1
Length=4085
Score = 448 bits (1152), Expect = 8e-143, Method: Composition-based stats.
Identities = 125/306 (41%), Positives = 183/306 (60%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+G RKMA PSG VE C+V+V G T LNGLWL D+VYCPRHVI ++ +Y+
Sbjct 2966 AGLRKMAQPSGFVEKCVVRVCYGNTVLNGLWLGDIVYCPRHVIASNTT-SAIDYDHEYSI 3024
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF + +G L V+G +M LK+KV N TP++ F ++ G+ F++LACY+G
Sbjct 3025 MRLHNFSIISGTAFLGVVGATMHGVTLKIKVSQTNMHTPRHSFRTLKSGEGFNILACYDG 3084
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
GV+ MR N+TI+GSF+NG+CGS G+N+ V F YMH +EL +G H G+ +G
Sbjct 3085 CAQGVFGVNMRTNWTIRGSFINGACGSPGYNLKNGEVEFVYMHQIELGSGSHVGSSFDGV 3144
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
YG F D+ Q + +TVNV+A+LYAA++NG W+L + +N A +
Sbjct 3145 MYGGFEDQPNLQVESANQMLTVNVVAFLYAAILNGCTWWLKGEKLFVEHYNEWAQANGFT 3204
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ + D L+A+TG+ V + +++ +L NG G+ ILG + L DEF+ +VV+Q
Sbjct 3205 AMNGE--DAFSILAAKTGVCVERLLHAIQ-VLNNGFGGKQILGYSSLNDEFSINEVVKQM 3261
Query 301 SGVTFQ 306
GV Q
Sbjct 3262 FGVNLQ 3267
>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus
229E OX=11137 GN=rep PE=1 SV=1
Length=6758
Score = 447 bits (1151), Expect = 1e-142, Method: Composition-based stats.
Identities = 125/306 (41%), Positives = 183/306 (60%), Gaps = 4/306 (1%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+G RKMA PSG VE C+V+V G T LNGLWL D+VYCPRHVI ++ +Y+
Sbjct 2966 AGLRKMAQPSGFVEKCVVRVCYGNTVLNGLWLGDIVYCPRHVIASNTT-SAIDYDHEYSI 3024
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF + +G L V+G +M LK+KV N TP++ F ++ G+ F++LACY+G
Sbjct 3025 MRLHNFSIISGTAFLGVVGATMHGVTLKIKVSQTNMHTPRHSFRTLKSGEGFNILACYDG 3084
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 180
GV+ MR N+TI+GSF+NG+CGS G+N+ V F YMH +EL +G H G+ +G
Sbjct 3085 CAQGVFGVNMRTNWTIRGSFINGACGSPGYNLKNGEVEFVYMHQIELGSGSHVGSSFDGV 3144
Query 181 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 240
YG F D+ Q + +TVNV+A+LYAA++NG W+L + +N A +
Sbjct 3145 MYGGFEDQPNLQVESANQMLTVNVVAFLYAAILNGCTWWLKGEKLFVEHYNEWAQANGFT 3204
Query 241 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 300
+ + D L+A+TG+ V + +++ +L NG G+ ILG + L DEF+ +VV+Q
Sbjct 3205 AMNGE--DAFSILAAKTGVCVERLLHAIQ-VLNNGFGGKQILGYSSLNDEFSINEVVKQM 3261
Query 301 SGVTFQ 306
GV Q
Sbjct 3262 FGVNLQ 3267
>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729
Score = 443 bits (1140), Expect = 4e-141, Method: Composition-based stats.
Identities = 135/307 (44%), Positives = 191/307 (62%), Gaps = 5/307 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG +KMA PSG VE C+V+V G+T LNG+WL D V CPRHVI S +L +Y+
Sbjct 2940 SGLKKMAQPSGCVERCVVRVCYGSTVLNGVWLGDTVTCPRHVIAPSTTVL-IDYDHAYST 2998
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF V V L V+G +M VL++KV +N TPK+ F ++PG +F++LACY G
Sbjct 2999 MRLHNFSVSHNGVFLGVVGVTMHGSVLRIKVSQSNVHTPKHVFKTLKPGDSFNILACYEG 3058
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDY-DCVSFCYMHHMELPTGVHAGTDLEG 179
SGV+ +R NFTIKGSF+NG+CGS G+N+ V FCY+H +EL +G H G+D G
Sbjct 3059 IASGVFGVNLRTNFTIKGSFINGACGSPGYNVRNDGTVEFCYLHQIELGSGAHVGSDFTG 3118
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 239
+ YG F D+ + Q + ++ NV+A+LYAA++NG RW+L ++ FN AM Y
Sbjct 3119 SVYGNFDDQPSLQVESANLMLSDNVVAFLYAALLNGCRWWLCSTRVNVDGFNEWAMANGY 3178
Query 240 EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQ 299
++ V+ L+A+TG++V + AS++ L G G+ ILG + L DEFT +VV+Q
Sbjct 3179 TSVSS--VECYSILAAKTGVSVEQLLASIQH-LHEGFGGKNILGYSSLCDEFTLAEVVKQ 3235
Query 300 CSGVTFQ 306
GV Q
Sbjct 3236 MYGVNLQ 3242
>sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus
NL63 OX=277944 GN=1a PE=1 SV=1
Length=4060
Score = 442 bits (1138), Expect = 6e-141, Method: Composition-based stats.
Identities = 135/307 (44%), Positives = 191/307 (62%), Gaps = 5/307 (2%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SG +KMA PSG VE C+V+V G+T LNG+WL D V CPRHVI S +L +Y+
Sbjct 2940 SGLKKMAQPSGCVERCVVRVCYGSTVLNGVWLGDTVTCPRHVIAPSTTVL-IDYDHAYST 2998
Query 61 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 120
HNF V V L V+G +M VL++KV +N TPK+ F ++PG +F++LACY G
Sbjct 2999 MRLHNFSVSHNGVFLGVVGVTMHGSVLRIKVSQSNVHTPKHVFKTLKPGDSFNILACYEG 3058
Query 121 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDY-DCVSFCYMHHMELPTGVHAGTDLEG 179
SGV+ +R NFTIKGSF+NG+CGS G+N+ V FCY+H +EL +G H G+D G
Sbjct 3059 IASGVFGVNLRTNFTIKGSFINGACGSPGYNVRNDGTVEFCYLHQIELGSGAHVGSDFTG 3118
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 239
+ YG F D+ + Q + ++ NV+A+LYAA++NG RW+L ++ FN AM Y
Sbjct 3119 SVYGNFDDQPSLQVESANLMLSDNVVAFLYAALLNGCRWWLCSTRVNVDGFNEWAMANGY 3178
Query 240 EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQ 299
++ V+ L+A+TG++V + AS++ L G G+ ILG + L DEFT +VV+Q
Sbjct 3179 TSVSS--VECYSILAAKTGVSVEQLLASIQH-LHEGFGGKNILGYSSLCDEFTLAEVVKQ 3235
Query 300 CSGVTFQ 306
GV Q
Sbjct 3236 MYGVNLQ 3242
>sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=1a PE=3
SV=1
Length=3951
Score = 398 bits (1023), Expect = 1e-125, Method: Composition-based stats.
Identities = 125/313 (40%), Positives = 174/313 (56%), Gaps = 13/313 (4%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ + D+L
Sbjct 2780 SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIYCPRHVL---GKFSGDQWNDVLNL 2836
Query 61 KSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
+NH F V + V L V+ ++ VL L+ AN +TPKYKF++ G +F++ Y
Sbjct 2837 ANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYG 2896
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G
Sbjct 2897 GTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMG 2956
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRW------FLNRFTTTLNDFNLV 233
FYG +VD + AQ D +T N++AWLYAA+I+ +L T +++D+N
Sbjct 2957 EFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSLPKWLESTTVSVDDYNKW 3016
Query 234 AMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTP 293
A + P + + LSA TG+ V + ++ + + G ILG EDE TP
Sbjct 3017 AGDNGFTPFSTST--AITKLSAITGVDVCKLLRTIM-VKNSQWGGDPILGQYNFEDELTP 3073
Query 294 FDVVRQCSGVTFQ 306
V Q GV Q
Sbjct 3074 ESVFNQIGGVRLQ 3086
>sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=1a PE=1 SV=1
Length=3951
Score = 398 bits (1023), Expect = 1e-125, Method: Composition-based stats.
Identities = 125/313 (40%), Positives = 174/313 (56%), Gaps = 13/313 (4%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ + D+L
Sbjct 2780 SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIYCPRHVL---GKFSGDQWNDVLNL 2836
Query 61 KSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
+NH F V + V L V+ ++ VL L+ AN +TPKYKF++ G +F++ Y
Sbjct 2837 ANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYG 2896
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G
Sbjct 2897 GTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMG 2956
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRW------FLNRFTTTLNDFNLV 233
FYG +VD + AQ D +T N++AWLYAA+I+ +L T +++D+N
Sbjct 2957 EFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSLPKWLESTTVSVDDYNKW 3016
Query 234 AMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTP 293
A + P + + LSA TG+ V + ++ + + G ILG EDE TP
Sbjct 3017 AGDNGFTPFSTST--AITKLSAITGVDVCKLLRTIM-VKNSQWGGDPILGQYNFEDELTP 3073
Query 294 FDVVRQCSGVTFQ 306
V Q GV Q
Sbjct 3074 ESVFNQIGGVRLQ 3086
>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep
PE=3 SV=1
Length=6629
Score = 397 bits (1020), Expect = 5e-125, Method: Composition-based stats.
Identities = 125/313 (40%), Positives = 174/313 (56%), Gaps = 13/313 (4%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ + D+L
Sbjct 2780 SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIYCPRHVL---GKFSGDQWNDVLNL 2836
Query 61 KSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
+NH F V + V L V+ ++ VL L+ AN +TPKYKF++ G +F++ Y
Sbjct 2837 ANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYG 2896
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G
Sbjct 2897 GTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMG 2956
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRW------FLNRFTTTLNDFNLV 233
FYG +VD + AQ D +T N++AWLYAA+I+ +L T +++D+N
Sbjct 2957 EFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSLPKWLESTTVSVDDYNKW 3016
Query 234 AMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTP 293
A + P + + LSA TG+ V + ++ + + G ILG EDE TP
Sbjct 3017 AGDNGFTPFSTST--AITKLSAITGVDVCKLLRTIM-VKNSQWGGDPILGQYNFEDELTP 3073
Query 294 FDVVRQCSGVTFQ 306
V Q GV Q
Sbjct 3074 ESVFNQIGGVRLQ 3086
>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1
SV=1
Length=6629
Score = 396 bits (1019), Expect = 5e-125, Method: Composition-based stats.
Identities = 125/313 (40%), Positives = 174/313 (56%), Gaps = 13/313 (4%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
SGF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ + D+L
Sbjct 2780 SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIYCPRHVL---GKFSGDQWNDVLNL 2836
Query 61 KSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
+NH F V + V L V+ ++ VL L+ AN +TPKYKF++ G +F++ Y
Sbjct 2837 ANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYG 2896
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G
Sbjct 2897 GTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMG 2956
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRW------FLNRFTTTLNDFNLV 233
FYG +VD + AQ D +T N++AWLYAA+I+ +L T +++D+N
Sbjct 2957 EFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSLPKWLESTTVSVDDYNKW 3016
Query 234 AMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTP 293
A + P + + LSA TG+ V + ++ + + G ILG EDE TP
Sbjct 3017 AGDNGFTPFSTST--AITKLSAITGVDVCKLLRTIM-VKNSQWGGDPILGQYNFEDELTP 3073
Query 294 FDVVRQCSGVTFQ 306
V Q GV Q
Sbjct 3074 ESVFNQIGGVRLQ 3086
>sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=1a PE=1 SV=1
Length=3953
Score = 393 bits (1010), Expect = 9e-124, Method: Composition-based stats.
Identities = 125/313 (40%), Positives = 171/313 (55%), Gaps = 13/313 (4%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+GF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ + D+L
Sbjct 2782 AGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVL---GKFSGDQWGDVLNL 2838
Query 61 KSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
+NH F V N V L V+ ++ VL L+ AN +TPKYKFV+ G +F++ Y
Sbjct 2839 ANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYG 2898
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G
Sbjct 2899 GTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMG 2958
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRW------FLNRFTTTLNDFNLV 233
FYG +VD + AQ D +T N++AWLYAA+I+ +L T ++ D+N
Sbjct 2959 EFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRW 3018
Query 234 AMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTP 293
A + P + + LSA TG+ V + ++ + ILG EDE TP
Sbjct 3019 ASDNGFTPFSTST--AITKLSAITGVDVCKLLRTIM-VKSAQWGSDPILGQYNFEDELTP 3075
Query 294 FDVVRQCSGVTFQ 306
V Q GV Q
Sbjct 3076 ESVFNQVGGVRLQ 3088
>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631
Score = 392 bits (1007), Expect = 3e-123, Method: Composition-based stats.
Identities = 125/313 (40%), Positives = 171/313 (55%), Gaps = 13/313 (4%)
Query 1 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 60
+GF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ + D+L
Sbjct 2782 AGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVL---GKFSGDQWGDVLNL 2838
Query 61 KSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 119
+NH F V N V L V+ ++ VL L+ AN +TPKYKFV+ G +F++ Y
Sbjct 2839 ANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYG 2898
Query 120 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 179
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G
Sbjct 2899 GTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMG 2958
Query 180 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRW------FLNRFTTTLNDFNLV 233
FYG +VD + AQ D +T N++AWLYAA+I+ +L T ++ D+N
Sbjct 2959 EFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRW 3018
Query 234 AMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTP 293
A + P + + LSA TG+ V + ++ + ILG EDE TP
Sbjct 3019 ASDNGFTPFSTST--AITKLSAITGVDVCKLLRTIM-VKSAQWGSDPILGQYNFEDELTP 3075
Query 294 FDVVRQCSGVTFQ 306
V Q GV Q
Sbjct 3076 ESVFNQVGGVRLQ 3088
>sp|G3XP90|CTPE_ASPNA Mitochondrial citrate transporter E OS=Aspergillus
niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144
/ LSHB Ac4 / NCTC 3858a / NRRL 328 / USDA 3528.7) OX=380704
GN=ctpE PE=3 SV=1
Length=310
Score = 32.2 bits (72), Expect = 6.1, Method: Composition-based stats.
Identities = 20/87 (23%), Positives = 32/87 (37%), Gaps = 6/87 (7%)
Query 134 FTIKGSFLNG---SCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQT 190
T G+F+ G +CG+V ++ V EL A G +G +
Sbjct 2 STTTGAFIAGGVAACGAVTVTHSFETVKIRLQLQGELQAKQDAAKKYRGVLHGV---KVI 58
Query 191 AQAAGTDTTITVNVLAWLYAAVINGDR 217
Q G A++Y ++NG R
Sbjct 59 LQNEGPRGLFRGIGSAYIYQVLLNGCR 85
Lambda K H a alpha
0.321 0.148 0.452 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0452 0.140 1.90 42.6 43.6
Effective search space used: 26429457978
Search has CONVERGED!
Database: uniprot_sprot.fasta
Posted date: Apr 3, 2024 12:05 PM
Number of letters in database: 206,678,396
Number of sequences in database: 571,282
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40