PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
570,157 sequences; 206,173,379 total letters
Results from round 1
Query= YP_009724389.1 orf1ab polyprotein [Severe acute respiratory syndrome
coronavirus 2]
Length=7096
Score E
Sequences producing significant alignments: (Bits) Value
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re... 14825 0.0
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res... 12978 0.0
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus... 12924 0.0
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus... 12917 0.0
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus... 12908 0.0
sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute resp... 9137 0.0
sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respi... 7474 0.0
sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus H... 7447 0.0
sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus R... 7445 0.0
sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus 2... 7442 0.0
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus... 6357 0.0
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res... 5991 0.0
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus... 5976 0.0
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus... 5612 0.0
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus... 5604 0.0
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi... 5427 0.0
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi... 5423 0.0
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir... 5406 0.0
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir... 5395 0.0
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir... 5394 0.0
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi... 5381 0.0
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir... 5341 0.0
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir... 5340 0.0
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir... 5337 0.0
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi... 5337 0.0
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir... 5261 0.0
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus... 4347 0.0
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir... 4306 0.0
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi... 4290 0.0
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir... 4258 0.0
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi... 4213 0.0
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir... 4188 0.0
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious... 4156 0.0
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou... 4155 0.0
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious... 4152 0.0
sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus H... 2550 0.0
sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respi... 2192 0.0
sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus H... 2172 0.0
sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronaviru... 1872 0.0
sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronaviru... 1871 0.0
sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus... 1860 0.0
sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus... 1859 0.0
sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus... 1858 0.0
sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus... 1834 0.0
sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronaviru... 1834 0.0
sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus 1... 1831 0.0
sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus H... 1828 0.0
sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronaviru... 1828 0.0
sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus... 1825 0.0
sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus... 1823 0.0
sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus... 1818 0.0
sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus 5... 1228 0.0
sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus... 1189 0.0
sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic ... 1185 0.0
sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus... 1181 0.0
sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmiss... 1127 0.0
sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious ... 1113 0.0
sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious b... 1113 0.0
sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious b... 1108 0.0
sp|P18457|R1AB_CVPFS Replicase polyprotein 1ab (Fragment) OS=Porc... 518 2e-162
sp|Q9WQ77|R1AB_CVRSD Replicase polyprotein 1ab (Fragment) OS=Rat ... 484 4e-154
sp|Q9WQ76|R1AB_CVTMI Replicase polyprotein 1ab (Fragment) OS=Turk... 445 2e-140
sp|P12723|R1AB_IBVK Replicase polyprotein 1ab (Fragment) OS=Avian... 439 4e-135
sp|P36697|R1AB_CVCAI Replicase polyprotein 1ab (Fragment) OS=Cani... 183 3e-51
sp|Q04158|R1AB_CVPR8 Replicase polyprotein 1ab (Fragment) OS=Porc... 127 3e-32
sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11... 137 4e-30
sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream vir... 133 1e-28
sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus 1 OX... 127 4e-27
sp|Q4J9D2|Y1252_SULAC Uncharacterized protein Saci_1252 OS=Sulfol... 73.2 1e-12
sp|Q97UU4|Y2899_SACS2 Uncharacterized protein SSO2899 OS=Saccharo... 72.8 2e-12
sp|Q8ZXT3|Y1111_PYRAE Uncharacterized protein PAE1111 OS=Pyrobacu... 72.8 2e-12
sp|Q9WYX8|Y508_THEMA Uncharacterized protein TM_0508 OS=Thermotog... 76.3 8e-12
sp|Q96XY5|Y2383_SULTO Uncharacterized protein STK_23830 OS=Sulfur... 67.0 2e-10
sp|P0C6F3|R1A_BEV Replicase polyprotein 1a OS=Berne virus OX=1115... 65.5 2e-08
sp|P36327|POLN_EEVV3 Polyprotein P1234 OS=Venezuelan equine encep... 63.2 1e-07
sp|Q8CAS9|PARP9_MOUSE Protein mono-ADP-ribosyltransferase PARP9 O... 62.8 1e-07
sp|P27282|POLN_EEVVT Polyprotein P1234 OS=Venezuelan equine encep... 62.4 2e-07
sp|P36328|POLN_EEVVP Polyprotein P1234 OS=Venezuelan equine encep... 62.4 2e-07
sp|A7MG20|YMDB_CROS8 O-acetyl-ADP-ribose deacetylase OS=Cronobact... 58.2 2e-07
sp|E1SDF1|YMDB1_PANVC O-acetyl-ADP-ribose deacetylase 1 OS=Pantoe... 57.0 5e-07
sp|A8AI35|YMDB_CITK8 O-acetyl-ADP-ribose deacetylase OS=Citrobact... 56.6 8e-07
sp|Q8V294|POLN_EEVVC Polyprotein P1234 OS=Venezuelan equine encep... 59.3 2e-06
sp|B6SFA4|MAA3_ARATH Probable helicase MAGATAMA 3 OS=Arabidopsis ... 58.9 2e-06
sp|C9Y0V8|YMDB_CROTZ O-acetyl-ADP-ribose deacetylase OS=Cronobact... 55.1 2e-06
sp|B5F961|YMDB_SALA4 O-acetyl-ADP-ribose deacetylase OS=Salmonell... 54.3 5e-06
sp|A4W960|YMDB_ENT38 O-acetyl-ADP-ribose deacetylase OS=Enterobac... 53.9 6e-06
sp|P67341|YMDB_SALTY O-acetyl-ADP-ribose deacetylase OS=Salmonell... 53.5 7e-06
sp|P67342|YMDB_SALTI O-acetyl-ADP-ribose deacetylase OS=Salmonell... 53.5 7e-06
sp|P0A8D6|YMDB_ECOLI O-acetyl-ADP-ribose deacetylase OS=Escherich... 53.1 9e-06
sp|P0A8D7|YMDB_ECOL6 O-acetyl-ADP-ribose deacetylase OS=Escherich... 53.1 9e-06
sp|P0A8D8|YMDB_ECO57 O-acetyl-ADP-ribose deacetylase OS=Escherich... 53.1 9e-06
sp|D3RKJ0|YMDB_KLEVT O-acetyl-ADP-ribose deacetylase OS=Klebsiell... 53.1 9e-06
sp|B5XXK9|YMDB_KLEP3 O-acetyl-ADP-ribose deacetylase OS=Klebsiell... 53.1 9e-06
sp|B4T2X8|YMDB_SALNS O-acetyl-ADP-ribose deacetylase OS=Salmonell... 53.1 1e-05
sp|Q9WJC7|POLN_EEVVM Polyprotein P1234 OS=Venezuelan equine encep... 56.6 1e-05
sp|Q460N5|PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14 ... 56.2 1e-05
sp|D5CE05|YMDB_ENTCC O-acetyl-ADP-ribose deacetylase OS=Enterobac... 52.0 3e-05
sp|Q72M93|Y3295_LEPIC Macro domain-containing protein LIC_13295 O... 51.6 3e-05
sp|Q8EYT0|Y4133_LEPIN Macro domain-containing protein LA_4133 OS=... 51.6 3e-05
sp|B5RBF3|YMDB_SALG2 O-acetyl-ADP-ribose deacetylase OS=Salmonell... 51.6 4e-05
sp|B7LT90|YMDB_ESCF3 O-acetyl-ADP-ribose deacetylase OS=Escherich... 51.2 5e-05
sp|Q0T5Z6|YMDB_SHIF8 O-acetyl-ADP-ribose deacetylase OS=Shigella ... 50.8 7e-05
sp|P0C6F4|R1A_BRV1 Replicase polyprotein 1a OS=Breda virus 1 OX=3... 53.5 1e-04
sp|D2TT52|YMDB_CITRI O-acetyl-ADP-ribose deacetylase OS=Citrobact... 50.1 1e-04
sp|Q32E73|YMDB_SHIDS O-acetyl-ADP-ribose deacetylase OS=Shigella ... 49.7 1e-04
sp|Q8RHQ2|Y1951_FUSNN Uncharacterized protein FN1951 OS=Fusobacte... 49.3 2e-04
sp|Q2EMV9|PAR14_MOUSE Protein mono-ADP-ribosyltransferase PARP14 ... 51.6 3e-04
sp|Q8Q0F9|Y177_METMA Macro domain-containing protein MM_0177 OS=M... 48.5 4e-04
sp|Q87JZ5|Y4103_VIBPA Macro domain-containing protein VPA0103 OS=... 47.8 7e-04
sp|Q8IXQ6|PARP9_HUMAN Protein mono-ADP-ribosyltransferase PARP9 O... 50.4 7e-04
sp|Q8RB30|Y995_CALS4 Macro domain-containing protein TTE0995 OS=C... 47.4 8e-04
sp|E1PL40|YMDB2_PANVC O-acetyl-ADP-ribose deacetylase 2 OS=Pantoe... 47.4 0.001
sp|Q8TQD0|Y1614_METAC Macro domain-containing protein MA_1614 OS=... 47.8 0.001
sp|Q92355|SEN1_SCHPO Helicase sen1 OS=Schizosaccharomyces pombe (... 49.7 0.001
sp|P38859|DNA2_YEAST DNA replication ATP-dependent helicase/nucle... 49.3 0.002
sp|Q8Y2K1|Y334_RALN1 Macro domain-containing protein RSc0334 OS=R... 46.2 0.002
sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 OS=Arabidopsis th... 48.5 0.003
sp|Q68772|RPOA_SHFV Replicase polyprotein 1ab OS=Simian hemorrhag... 48.1 0.004
sp|Q9EYI6|Y189_STRNO Macro domain-containing protein in sno 5'reg... 45.4 0.005
sp|Q9WJB2|RPOA_PRRSR Replicase polyprotein 1ab OS=Porcine reprodu... 47.8 0.006
sp|Q8KAE4|Y2219_CHLTE Macro domain-containing protein CT2219 OS=C... 44.7 0.007
sp|Q97AU0|Y719_THEVO Uncharacterized protein TV0719 OS=Thermoplas... 45.1 0.007
sp|Q93SX7|Y189_ACISE Macro domain-containing protein OS=Acinetoba... 44.7 0.008
sp|Q88SK6|Y3408_LACPL Macro domain-containing protein lp_3408 OS=... 44.3 0.010
sp|Q985D2|Y7730_RHILO Macro domain-containing protein mll7730 OS=... 44.3 0.010
sp|Q8B912|RPOA_PRRSB Replicase polyprotein 1ab OS=Porcine reprodu... 47.0 0.011
sp|P30771|RENT1_YEAST ATP-dependent helicase NAM7 OS=Saccharomyce... 46.6 0.011
sp|Q9YN02|RPOA_PRRS1 Replicase polyprotein 1ab OS=Porcine reprodu... 46.6 0.013
sp|O59182|Y1513_PYRHO Uncharacterized protein PH1513 OS=Pyrococcu... 43.5 0.021
sp|Q9V0Y3|Y656_PYRAB Uncharacterized protein PYRAB06560 OS=Pyroco... 43.1 0.026
sp|P19811|RPOA_EAVBU Replicase polyprotein 1ab OS=Equine arteriti... 45.4 0.028
sp|P27283|POLN_SINDO Polyprotein P1234 OS=Sindbis virus subtype O... 45.4 0.031
sp|Q8P5Z8|Y3184_XANCP Macro domain-containing protein XCC3184 OS=... 42.7 0.032
sp|Q8PHB6|Y3343_XANAC Macro domain-containing protein XAC3343 OS=... 42.7 0.035
sp|Q9HJ67|Y1105_THEAC Uncharacterized protein Ta1105 OS=Thermopla... 42.7 0.043
sp|Q8BCR0|POLN_RUBVN Non-structural polyprotein p200 OS=Rubella v... 44.3 0.056
sp|Q6PAV8|MACD2_XENLA ADP-ribose glycohydrolase MACROD2 OS=Xenopu... 43.5 0.068
sp|Q9BQ69|MACD1_HUMAN ADP-ribose glycohydrolase MACROD1 OS=Homo s... 42.7 0.088
sp|Q86924|POLN_AURAV Polyprotein P1234 OS=Aura virus OX=44158 PE=... 43.9 0.089
sp|P13889|POLN_RUBVT Non-structural polyprotein p200 OS=Rubella v... 43.5 0.11
sp|Q9ZBG3|Y6450_STRCO Macro domain-containing protein SCO6450 OS=... 41.2 0.12
sp|Q8K4G6|MACD1_RAT ADP-ribose glycohydrolase MACROD1 (Fragment) ... 42.0 0.14
sp|O40955|POLN_RUBVR Non-structural polyprotein p200 OS=Rubella v... 43.1 0.14
sp|P03317|POLN_SINDV Polyprotein P1234 OS=Sindbis virus OX=11034 ... 42.4 0.22
sp|A0A1P8ASY1|JHS1_ARATH DNA replication ATP-dependent helicase/n... 42.4 0.23
sp|O28751|Y1521_ARCFU ADP-ribose glycohydrolase AF_1521 OS=Archae... 40.4 0.24
sp|Q306W6|POLN_EEEV1 Polyprotein P1234 OS=Eastern equine encephal... 42.4 0.26
sp|Q44020|YGB2_CUPNE Macro domain-containing protein in gbd 3'reg... 40.0 0.27
sp|Q9YBE9|Y1648_AERPE Uncharacterized protein APE_1648.1 OS=Aerop... 40.0 0.33
sp|Q2KHU5|MACD1_BOVIN ADP-ribose glycohydrolase MACROD1 OS=Bos ta... 40.8 0.35
sp|Q9BYK8|HELZ2_HUMAN Helicase with zinc finger domain 2 OS=Homo ... 41.6 0.44
sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens ... 41.2 0.58
sp|P13896|POLN_WEEV Polyprotein P1234 OS=Western equine encephali... 41.2 0.60
sp|P18479|POLG_ZYMVC Genome polyprotein OS=Zucchini yellow mosaic... 41.2 0.61
sp|Q9HEH1|RENT1_NEUCR Regulator of nonsense transcripts 1 homolog... 40.8 0.61
sp|Q9VHM2|VP35L_DROME VPS35 endosomal protein sorting factor-like... 40.8 0.67
sp|Q09449|YQ12_CAEEL Uncharacterized ATP-dependent helicase C05C1... 40.8 0.71
sp|A2AKX3|SETX_MOUSE Probable helicase senataxin OS=Mus musculus ... 40.4 0.90
sp|Q9FJR0|RENT1_ARATH Regulator of nonsense transcripts 1 homolog... 40.4 0.97
sp|Q922B1|MACD1_MOUSE ADP-ribose glycohydrolase MACROD1 OS=Mus mu... 39.7 1.0
sp|P32644|ECM32_YEAST Putative ATP-dependent RNA helicase ECM32 O... 40.0 1.1
sp|Q306W8|POLN_EEEV8 Polyprotein P1234 OS=Eastern equine encephal... 40.0 1.1
sp|Q9HXU7|Y3693_PSEAE Macro domain-containing protein PA3693 OS=P... 38.1 1.3
sp|Q09820|RENT1_SCHPO ATP-dependent helicase upf1 OS=Schizosaccha... 39.7 1.6
sp|Q98TR3|RENT1_TAKRU Putative regulator of nonsense transcripts ... 38.5 3.0
sp|Q9RUV0|PPDE_DEIRA Phosphatase/phosphodiesterase DR_1281 OS=Dei... 37.7 3.1
sp|Q06502|RPOA_LDVC Replicase polyprotein 1ab OS=Lactate dehydrog... 38.5 3.1
sp|P18478|POLG_WMV2U Genome polyprotein (Fragment) OS=Watermelon ... 38.5 3.3
sp|Q54I89|RENT1_DICDI Regulator of nonsense transcripts 1 OS=Dict... 38.5 3.4
sp|Q99IE5|POLN_RUBVV Non-structural polyprotein p200 OS=Rubella v... 38.5 3.4
sp|Q99IE7|POLN_RUBVO Non-structural polyprotein p200 OS=Rubella v... 38.5 3.4
sp|Q4QXJ8|POLN_EEEVF Polyprotein P1234 OS=Eastern equine encephal... 38.5 3.5
sp|Q9KHE2|Y189_STRGR Macro domain-containing protein in non 5'reg... 36.6 3.7
sp|O76512|RENT1_CAEEL Regulator of nonsense transcripts 1 OS=Caen... 38.1 3.7
sp|Q7TZB9|Y1934_MYCBO Uncharacterized protein Mb1934c OS=Mycobact... 37.7 4.0
sp|P9WK29|Y1899_MYCTU Uncharacterized protein Rv1899c OS=Mycobact... 37.7 4.0
sp|P9WK28|Y1899_MYCTO Uncharacterized protein MT1950 OS=Mycobacte... 37.7 4.1
sp|P26627|R1AB_CVMJD Replicase polyprotein 1ab (Fragment) OS=Muri... 37.7 4.2
sp|E9QAM5|HELZ2_MOUSE Helicase with zinc finger domain 2 OS=Mus m... 38.1 4.2
sp|Q6X2U4|POLN_RUBVB Non-structural polyprotein p200 OS=Rubella v... 38.1 4.4
sp|Q8Y3S3|Y2759_LISMO Macro domain-containing protein lmo2759 OS=... 36.6 4.4
sp|Q04561|RPOA_PRRSL Replicase polyprotein 1ab OS=Porcine reprodu... 38.1 4.6
sp|A0A339|NDHK_COFAR NAD(P)H-quinone oxidoreductase subunit K, ch... 37.0 4.7
sp|Q89330|POLG_ZYMVR Genome polyprotein OS=Zucchini yellow mosaic... 38.1 4.9
sp|Q6X2U2|POLN_RUBVC Non-structural polyprotein p200 OS=Rubella v... 38.1 4.9
sp|A0A0D2UG83|H2AY_CAPO3 Histone macroH2A1.1 OS=Capsaspora owczar... 37.4 5.1
sp|Q926Y8|Y2902_LISIN Macro domain-containing protein lin2902 OS=... 36.2 5.4
sp|A0MD28|RPOA_PRRSS Replicase polyprotein 1ab OS=Porcine reprodu... 37.7 5.8
sp|Q3UYG8|MACD2_MOUSE ADP-ribose glycohydrolase MACROD2 OS=Mus mu... 37.4 6.0
sp|B4S3G9|PDXJ_PROA2 Pyridoxine 5'-phosphate synthase OS=Prosthec... 36.6 6.0
sp|Q71W03|Y2748_LISMF Macro domain-containing protein LMOf2365_27... 35.8 6.4
sp|A1Z1Q3|MACD2_HUMAN ADP-ribose glycohydrolase MACROD2 OS=Homo s... 37.0 6.9
sp|Q83017|RPOA_LDVP Replicase polyprotein 1ab OS=Lactate dehydrog... 37.4 7.5
sp|Q9J6K9|POLN_RUBVD Non-structural polyprotein p200 OS=Rubella v... 37.4 7.9
sp|Q86500|POLN_RUBVM Non-structural polyprotein p200 OS=Rubella v... 37.0 9.1
sp|Q3ZX83|TIG_DEHMC Trigger factor OS=Dehalococcoides mccartyi (s... 36.6 9.7
sp|Q5ZKG3|DNA2_CHICK DNA replication ATP-dependent helicase/nucle... 37.0 9.8
sp|B0C385|RPOC2_ACAM1 DNA-directed RNA polymerase subunit beta' O... 37.0 9.9
>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1
SV=1
Length=7096
Score = 14825 bits (38475), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 7096/7096 (100%), Positives = 7096/7096 (100%), Gaps = 0/7096 (0%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV
Sbjct 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK
Sbjct 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW
Sbjct 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI
Sbjct 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL
Sbjct 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC
Sbjct 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF
Sbjct 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA
Sbjct 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY
Sbjct 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV
Sbjct 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC
Sbjct 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG
Sbjct 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN 840
TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN
Sbjct 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN 840
Query 841 ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW 900
ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW
Sbjct 841 ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW 900
Query 901 SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL 960
SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL
Sbjct 901 SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL 960
Query 961 EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV 1020
EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV
Sbjct 961 EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV 1020
Query 1021 QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN
Sbjct 1021 QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
Query 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ 1140
NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ
Sbjct 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ 1140
Query 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE 1200
HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE
Sbjct 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE 1200
Query 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN 1260
QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN
Sbjct 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN 1260
Query 1261 GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV 1320
GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV
Sbjct 1261 GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV 1320
Query 1321 PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA 1380
PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA
Sbjct 1321 PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA 1380
Query 1381 HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND 1440
HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND
Sbjct 1381 HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND 1440
Query 1441 LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH 1500
LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH
Sbjct 1441 LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH 1500
Query 1501 FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL 1560
FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL
Sbjct 1501 FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL 1560
Query 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV
Sbjct 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
Query 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL
Sbjct 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
Query 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN
Sbjct 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
Query 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ
Sbjct 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
Query 1801 ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK 1860
ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK
Sbjct 1801 ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK 1860
Query 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY 1920
GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY
Sbjct 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY 1920
Query 1921 PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK
Sbjct 1921 PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
Query 1981 KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA 2040
KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA
Sbjct 1981 KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA 2040
Query 2041 CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV
Sbjct 2041 CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
Query 2101 DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC 2160
DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC
Sbjct 2101 DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC 2160
Query 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS
Sbjct 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
Query 2221 PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT 2280
PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT
Sbjct 2221 PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT 2280
Query 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV
Sbjct 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
Query 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV
Sbjct 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA
Sbjct 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH
Sbjct 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV
Sbjct 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG
Sbjct 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
Query 2641 FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN 2700
FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN
Sbjct 2641 FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN 2700
Query 2701 AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL 2760
AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL
Sbjct 2701 AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL 2760
Query 2761 KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI 2820
KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI
Sbjct 2761 KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI 2820
Query 2821 ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD 2880
ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD
Sbjct 2821 ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD 2880
Query 2881 FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE 2940
FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE
Sbjct 2881 FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE 2940
Query 2941 GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST 3000
GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST
Sbjct 2941 GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST 3000
Query 3001 SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL
Sbjct 3001 SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
Query 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV
Sbjct 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
Query 3121 SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL 3180
SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL
Sbjct 3121 SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL 3180
Query 3181 CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND 3240
CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND
Sbjct 3181 CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND 3240
Query 3241 FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY 3300
FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY
Sbjct 3241 FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY 3300
Query 3301 CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK 3360
CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK
Sbjct 3301 CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK 3360
Query 3361 TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV 3420
TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV
Sbjct 3361 TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV 3420
Query 3421 SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR 3480
SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR
Sbjct 3421 SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR 3480
Query 3481 WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN
Sbjct 3481 WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
Query 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW
Sbjct 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
Query 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV
Sbjct 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
Query 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK
Sbjct 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
Query 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM
Sbjct 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
Query 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL
Sbjct 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
Query 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL
Sbjct 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
Query 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA
Sbjct 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
Query 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED
Sbjct 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
Query 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY
Sbjct 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
Query 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ 4140
KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ
Sbjct 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ 4140
Query 4141 NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD 4200
NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD
Sbjct 4141 NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD 4200
Query 4201 GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV 4260
GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV
Sbjct 4201 GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV 4260
Query 4261 PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES 4320
PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES
Sbjct 4261 PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES 4320
Query 4321 FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG 4380
FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG
Sbjct 4321 FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG 4380
Query 4381 CSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKF 4440
CSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKF
Sbjct 4381 CSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKF 4440
Query 4441 LKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDG 4500
LKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDG
Sbjct 4441 LKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDG 4500
Query 4501 DMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVEN 4560
DMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVEN
Sbjct 4501 DMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVEN 4560
Query 4561 PDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPG 4620
PDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPG
Sbjct 4561 PDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPG 4620
Query 4621 SGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFK 4680
SGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFK
Sbjct 4621 SGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFK 4680
Query 4681 YWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHF 4740
YWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHF
Sbjct 4681 YWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHF 4740
Query 4741 RELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQ 4800
RELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQ
Sbjct 4741 RELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQ 4800
Query 4801 TVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQ 4860
TVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQ
Sbjct 4801 TVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQ 4860
Query 4861 LLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALF 4920
LLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALF
Sbjct 4861 LLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALF 4920
Query 4921 AYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVV 4980
AYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVV
Sbjct 4921 AYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVV 4980
Query 4981 IGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSL 5040
IGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSL
Sbjct 4981 IGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSL 5040
Query 5041 SHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALL 5100
SHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALL
Sbjct 5041 SHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALL 5100
Query 5101 STDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNS 5160
STDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNS
Sbjct 5101 STDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNS 5160
Query 5161 TYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVY 5220
TYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVY
Sbjct 5161 TYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVY 5220
Query 5221 LPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYI 5280
LPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYI
Sbjct 5221 LPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYI 5280
Query 5281 RKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRC 5340
RKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRC
Sbjct 5281 RKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRC 5340
Query 5341 GACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHK 5400
GACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHK
Sbjct 5341 GACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHK 5400
Query 5401 PPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAE 5460
PPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAE
Sbjct 5401 PPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAE 5460
Query 5461 TLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIG 5520
TLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIG
Sbjct 5461 TLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIG 5520
Query 5521 EYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTL 5580
EYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTL
Sbjct 5521 EYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTL 5580
Query 5581 NISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDA 5640
NISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDA
Sbjct 5581 NISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDA 5640
Query 5641 LCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEI 5700
LCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEI
Sbjct 5641 LCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEI 5700
Query 5701 SMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDM 5760
SMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDM
Sbjct 5701 SMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDM 5760
Query 5761 FLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVV 5820
FLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVV
Sbjct 5761 FLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVV 5820
Query 5821 REFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC 5880
REFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC
Sbjct 5821 REFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC 5880
Query 5881 NVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVI 5940
NVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVI
Sbjct 5881 NVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVI 5940
Query 5941 TGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFIT 6000
TGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFIT
Sbjct 5941 TGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFIT 6000
Query 6001 REEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSR 6060
REEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSR
Sbjct 6001 REEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSR 6060
Query 6061 VSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSM 6120
VSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSM
Sbjct 6061 VSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSM 6120
Query 6121 KYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQS 6180
KYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQS
Sbjct 6121 KYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQS 6180
Query 6181 NHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHM 6240
NHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHM
Sbjct 6181 NHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHM 6240
Query 6241 VVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSD 6300
VVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSD
Sbjct 6241 VVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSD 6300
Query 6301 KFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSA 6360
KFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSA
Sbjct 6301 KFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSA 6360
Query 6361 FVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYL 6420
FVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYL
Sbjct 6361 FVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYL 6420
Query 6421 DAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIIN 6480
DAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIIN
Sbjct 6421 DAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIIN 6480
Query 6481 NTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDY 6540
NTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDY
Sbjct 6481 NTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDY 6540
Query 6541 KRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSV 6600
KRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSV
Sbjct 6541 KRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSV 6600
Query 6601 KGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQ 6660
KGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQ
Sbjct 6601 KGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQ 6660
Query 6661 MEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDF 6720
MEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDF
Sbjct 6661 MEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDF 6720
Query 6721 IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEIS 6780
IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEIS
Sbjct 6721 IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEIS 6780
Query 6781 FMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMM 6840
FMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMM
Sbjct 6781 FMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMM 6840
Query 6841 NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND 6900
NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND
Sbjct 6841 NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND 6900
Query 6901 FVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLA 6960
FVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLA
Sbjct 6901 FVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLA 6960
Query 6961 LGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGY 7020
LGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGY
Sbjct 6961 LGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGY 7020
Query 7021 VMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLII 7080
VMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLII
Sbjct 7021 VMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLII 7080
Query 7081 RENNRVVISSDVLVNN 7096
RENNRVVISSDVLVNN
Sbjct 7081 RENNRVVISSDVLVNN 7096
>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score = 12978 bits (33681), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 6117/7103 (86%), Positives = 6590/7103 (93%), Gaps = 37/7103 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA + HGH +VELVAE++GIQYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGK+ CTLSEQLD+I++KRGVYCCR+HEHEIAW
Sbjct 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVASP ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + E+GPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+Q+S+L+PL F S+A
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIF+RTL+ A +S+ LQ+AA+TILDGIS+ SLRL+DAM++TSDL TN++++MAY
Sbjct 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ TSQWL+N+ GT EKL+P+ +W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVC+NGLMLLEIKD E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV EVQGYK+V
Sbjct 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ-YEYGTEDDYQGK 958
WS+AT+YLFD++GE +S MYCSFYPPDE+EE+ EEE T +EYGTEDDYQG
Sbjct 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
Query 959 PLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
PLEFGA++ ++ EEE+EEDWLDD ++Q+ E+
Sbjct 961 PLEFGASAETVRVEEEEEEDWLDDTTEQS-------------------EI-----EPEPE 996
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
VN F+GYLKLTDNV IK DIV+EA+ P V+VNAAN++LKHGGGVAGALNKA
Sbjct 997 PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKA 1056
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
TN AMQ ESDDYI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYENF
Sbjct 1057 TNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENF 1116
Query 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
N ++LLAPLLSAGIFGA P+ SL+VCV TVRT VY+AV DK LY+++V +L+ +
Sbjct 1117 NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPR- 1175
Query 1199 VEQKIAEIPKEEVKPFITESK---PSVEQRKQDDK-KIKACVEEVTTTLEETKFLTENLL 1254
E PK+E P +SK SV Q+ D K KIKAC++EVTTTLEETKFLT LL
Sbjct 1176 -----VEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLL 1230
Query 1255 LYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLA 1314
L+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML+
Sbjct 1231 LFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLS 1290
Query 1315 KALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWN 1374
+AL+KVP D YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSWN
Sbjct 1291 RALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWN 1350
Query 1375 LREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASL 1434
LREMLAHAEETRKLMP+C++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS+
Sbjct 1351 LREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASI 1410
Query 1435 INTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS 1494
I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSSS
Sbjct 1411 ITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSS 1470
Query 1495 KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVITF 1553
KT EEHF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGEV++
Sbjct 1471 KTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSL 1530
Query 1554 DNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSH 1613
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH +H
Sbjct 1531 DKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNH 1590
Query 1614 EGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNN 1673
EGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNN
Sbjct 1591 EGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN 1650
Query 1674 CYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMS 1733
CYL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM+
Sbjct 1651 CYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMT 1710
Query 1734 YLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQA 1793
+L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+ A
Sbjct 1711 HLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDA 1770
Query 1794 TKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALL 1853
T+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA L
Sbjct 1771 TQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHL 1830
Query 1854 TKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPID 1913
TK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPID
Sbjct 1831 TKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPID 1890
Query 1914 LVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYK 1973
LVP QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY+
Sbjct 1891 LVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYR 1950
Query 1974 HYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDA 2033
HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1951 HYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDT 2010
Query 2034 QGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHT 2093
QGMDNLACE +P SEEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+GH
Sbjct 2011 QGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHE 2070
Query 2094 DLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTT 2153
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + TT
Sbjct 2071 DLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITT 2130
Query 2154 TNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEA 2213
+N R RV NYMPY FTLL QLCTFT+STNSRI+AS+PTTIAKN+VKSV K CL+A
Sbjct 2131 SNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
Query 2214 SFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNS 2273
NY+KSP FSKL I +W LLLS+CLGSLI TAA GVL+SN G PSYC G RE YLNS
Sbjct 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNS 2250
Query 2274 TNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYIL 2333
+NVT +C GS PCS+CLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+L
Sbjct 2251 SNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYML 2310
Query 2334 FTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYV 2393
FT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY+
Sbjct 2311 FTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYI 2370
Query 2394 WKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCV 2453
WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC+
Sbjct 2371 WKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCL 2430
Query 2454 NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTY 2513
NCDTFC GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV VKNG++HLYFDKAGQKTY
Sbjct 2431 NCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTY 2490
Query 2514 ERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLD 2573
ERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES++KSASVYYSQLMCQPILLLD
Sbjct 2491 ERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLD 2550
Query 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
QALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF
Sbjct 2551 QALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTF 2610
Query 2634 ISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACID 2693
+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACID
Sbjct 2611 VSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACID 2670
Query 2694 CSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNV 2753
C+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV
Sbjct 2671 CNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNV 2730
Query 2754 VTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAID 2813
+TTKI+LKGGKIV+ K ++K TL+ + A + Y++ PVH +S H +++EIIGYKAI
Sbjct 2731 ITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQ 2790
Query 2814 GGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTI 2873
GVTRDI STD CFANKHA FD WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT+
Sbjct 2791 DGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTV 2850
Query 2874 LRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC 2933
LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYC
Sbjct 2851 LRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYC 2910
Query 2934 YDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
YDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2911 YDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE 2970
Query 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
G+C+STSGRWVLNN++YR+L GVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+
Sbjct 2971 VGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGII 3030
Query 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
AI+VTC AYYFM+FRR FGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYSV YLYLT
Sbjct 3031 AILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLT 3090
Query 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFS 3173
FY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNGV+FS
Sbjct 3091 FYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFS 3150
Query 3174 TFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCH 3233
TFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCH
Sbjct 3151 TFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCH 3210
Query 3234 LAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
LAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL
Sbjct 3211 LAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3270
Query 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
WLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LK
Sbjct 3271 WLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLK 3330
Query 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
VDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGF
Sbjct 3331 VDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGF 3390
Query 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
NIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYA
Sbjct 3391 NIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYA 3450
Query 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKE
Sbjct 3451 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
Query 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
LLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+
Sbjct 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLI 3570
Query 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMV
Sbjct 3571 LVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMV 3630
Query 3654 YMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMN 3713
YMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMN
Sbjct 3631 YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMN 3690
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITG
Sbjct 3691 VITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
NTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+
Sbjct 3751 NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKS 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ
Sbjct 3811 SIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPS 3953
LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPS
Sbjct 3871 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPS 3930
Query 3954 YAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 4013
YAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY
Sbjct 3931 YAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 3990
Query 4014 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4073
KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV
Sbjct 3991 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4050
Query 4074 IPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 4133
+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRA
Sbjct 4051 VPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRA 4110
Query 4134 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKW 4193
NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLKW
Sbjct 4111 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKW 4170
Query 4194 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4253
ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ
Sbjct 4171 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4230
Query 4254 AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
AGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE
Sbjct 4231 AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4290
Query 4314 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVC 4373
ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVC
Sbjct 4291 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 4350
Query 4374 GMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDK 4433
GMWKGYGCSCDQLREP++QSADA +FLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYN+K
Sbjct 4351 GMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEK 4410
Query 4434 VAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDF 4493
VAGFAKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+KDCPAVA HDF
Sbjct 4411 VAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDF 4470
Query 4494 FKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD 4553
FKFR+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD
Sbjct 4471 FKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD 4530
Query 4554 WYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGD 4613
WYDFVENPDILRVYANLGERVRQ+LLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWYDFGD
Sbjct 4531 WYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGD 4590
Query 4614 FIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLK 4673
F+Q PG GVP+VDSYYSLLMPILTLTRAL AESH+D DL KP IKWDLLKYDFTEERL
Sbjct 4591 FVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLC 4650
Query 4674 LFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV 4733
LFDRYFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV
Sbjct 4651 LFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV 4710
Query 4734 VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL 4793
VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL
Sbjct 4711 VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL 4770
Query 4794 TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP 4853
TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP
Sbjct 4771 TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP 4830
Query 4854 TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY 4913
TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY
Sbjct 4831 TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY 4890
Query 4914 EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA 4973
EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA
Sbjct 4891 EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA 4950
Query 4974 TRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARK 5033
TRGATVVIGTSKFYGGWHNMLKTVYSDVE PHLMGWDYPKCDRAMPNMLRIMASLVLARK
Sbjct 4951 TRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARK 5010
Query 5034 HTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT 5093
H TCC+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT
Sbjct 5011 HNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT 5070
Query 5094 ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDD 5153
ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV+EFYAYLRKHFSMMILSDD
Sbjct 5071 ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDD 5130
Query 5154 AVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK 5213
AVVC+NS YA+QGLVASIKNFK+VLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK
Sbjct 5131 AVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK 5190
Query 5214 QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF 5273
QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF
Sbjct 5191 QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF 5250
Query 5274 HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN 5333
HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN
Sbjct 5251 HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN 5310
Query 5334 SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS 5393
SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS
Sbjct 5311 SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS 5370
Query 5394 YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER 5453
YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER
Sbjct 5371 YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER 5430
Query 5454 LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK 5513
LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK
Sbjct 5431 LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK 5490
Query 5514 NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI 5573
NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI
Sbjct 5491 NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI 5550
Query 5574 TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC 5633
TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC
Sbjct 5551 TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC 5610
Query 5634 SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD 5693
SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD
Sbjct 5611 SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD 5670
Query 5694 IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM 5753
IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM
Sbjct 5671 IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM 5730
Query 5754 KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN 5813
KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN
Sbjct 5731 KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN 5790
Query 5814 RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT 5873
RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT
Sbjct 5791 RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT 5850
Query 5874 TETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF 5933
TETAHSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF
Sbjct 5851 TETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF 5910
Query 5934 KDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG 5993
KDCSK+ITGLHPTQAPTHLSVD KFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG
Sbjct 5911 KDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG 5970
Query 5994 YPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTP 6053
YPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAVPTGYVDT
Sbjct 5971 YPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTE 6030
Query 6054 NNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAH 6113
NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFVLWAH
Sbjct 6031 NNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAH 6090
Query 6114 GFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWG 6173
GFELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPFMIDVQQWG
Sbjct 6091 GFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWG 6150
Query 6174 FTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAA 6233
FTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDEL++N+A
Sbjct 6151 FTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSA 6210
Query 6234 CRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFY 6293
CRKVQHMVVK+ALLADKFPVLHDIGNPKAIKCVPQA+VEWKFYDAQPCSDKAYKIEELFY
Sbjct 6211 CRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFY 6270
Query 6294 SYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT 6353
SYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT
Sbjct 6271 SYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT 6330
Query 6354 PAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA 6413
PAFDKSAF NLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA
Sbjct 6331 PAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA 6390
Query 6414 NEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGE 6473
NEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQSLENVA+NVVNKGHFDG GE
Sbjct 6391 NEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGE 6450
Query 6474 VPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAA 6533
PVSIINN VYTKVDG+DVE+FENKTTLPVNVAFELWAKRNIKPVPE+KILNNLGVDIAA
Sbjct 6451 APVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAA 6510
Query 6534 NTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGV 6593
NTVIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ LTV FDGRV+GQVDLFRNARNGV
Sbjct 6511 NTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGV 6570
Query 6594 LITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQ 6653
LITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQSR+L+
Sbjct 6571 LITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLE 6630
Query 6654 EFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKES 6713
+FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR ++S
Sbjct 6631 DFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDS 6690
Query 6714 PFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVT 6773
P +LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV+SKVVKVT
Sbjct 6691 PLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVT 6750
Query 6774 IDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSAT 6833
IDY EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG++A
Sbjct 6751 IDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAV 6810
Query 6834 LPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL 6893
+PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL
Sbjct 6811 IPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL 6870
Query 6894 VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICG 6953
VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDP+TK+VTKENDSKEGFFTY+CG
Sbjct 6871 VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCG 6930
Query 6954 FIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKP 7013
FI+QKLALGGS+A+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NYLGKP
Sbjct 6931 FIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKP 6990
Query 7014 REQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLL 7073
+EQIDGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI SLL
Sbjct 6991 KEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLL 7050
Query 7074 SKGRLIIRENNRVVISSDVLVNN 7096
KGRLIIRENNRVV+SSD+LVNN
Sbjct 7051 EKGRLIIRENNRVVVSSDILVNN 7073
>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071
Score = 12924 bits (33542), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 6093/7104 (86%), Positives = 6580/7104 (93%), Gaps = 41/7104 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK GTCG+VE+EKGV
Sbjct 1 MESLVLGINEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKSGTCGIVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQ EQPYVFIKRSDA+ HGH + ELVAEL+G+QYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQPEQPYVFIKRSDAQGTDHGHRVRELVAELDGVQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHS+G DLKS+DLGDELGTDP ED+++NWNTKH SGV REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGVLRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A TRYVDNNFCGPDGYPLECIKDLLARAGK+ CTLSEQLD+I++KRGVYCCR+H HEIAW
Sbjct 181 ALTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCRDHGHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TCGYL
Sbjct 301 RSVYPVATPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVSEGPNTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + E+GPEHS A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSAADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF+LNEE+AIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFQLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+ +S+L+PL F S+A
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPIKGAWNIGQHRSVLTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIFSRTL+ A +S+ LQ+AA+TILD IS+ SLRL+DAM++TS+L TN++++MAY
Sbjct 541 AGVIRSIFSRTLDAANHSIPDLQRAAVTILDSISEQSLRLVDAMVYTSNLLTNSVIIMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ TSQWL+N+ T EKL+P+ W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 VTGGLVQQTSQWLSNLLDTTVEKLRPIFAWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNIKDCVKCFVDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAVVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVCINGLMLLEIK E+YCAL+P ++ TNN F LKGGAPTK VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCINGLMLLEIKANEQYCALSPGLLATNNVFRLKGGAPTKGVTFGEDTVVEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEP--STQYEYGTEDDYQG 957
WS+AT+YLFD+SGE KL+S MYCSFYPPDE+E+ + EEEE + ++EYGTE+DY+G
Sbjct 901 WSVATFYLFDDSGEEKLSSRMYCSFYPPDEEEDCEEYEEEEEVSERTCEHEYGTEEDYKG 960
Query 958 KPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELT 1017
PLEFGA++ +Q EE++EEDWLDD + +
Sbjct 961 LPLEFGASTDIIQVEEQEEEDWLDDAVEAEPEPE-------------------------- 994
Query 1018 PVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
+ VN +GYLKLTDNV IK DIVEEA+ P V+VNAAN++LKHGGGVAGALNK
Sbjct 995 -PLHEEPVNQLTGYLKLTDNVAIKCVDIVEEAQNANPMVIVNAANIHLKHGGGVAGALNK 1053
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
ATN AMQ ESD YI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYEN
Sbjct 1054 ATNGAMQKESDHYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYEN 1113
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK 1197
FN ++LLAPLLSAGIFGA P+ SL++CV TVRT VY+ V DK LY+++V +L+ K
Sbjct 1114 FNSQDILLAPLLSAGIFGAKPLQSLQMCVQTVRTQVYIVVNDKVLYEQVVMDYLDSLKPK 1173
Query 1198 QVEQKIAEIPKEEVKP---FITESKPSVEQRKQDDK-KIKACVEEVTTTLEETKFLTENL 1253
E PK+EV P + + SV Q+ D K KIKAC++EVTTTLEETKFLT L
Sbjct 1174 ------VEAPKQEVLPKAEYPKVDEKSVVQKTIDVKPKIKACIDEVTTTLEETKFLTNKL 1227
Query 1254 LLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEML 1313
LL+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML
Sbjct 1228 LLFTDINGKLYQDSKNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEML 1287
Query 1314 AKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSW 1373
++AL+KVP + YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSW
Sbjct 1288 SRALKKVPINEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSETPNAKEEILGTVSW 1347
Query 1374 NLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVAS 1433
NLREMLAHAEETRKLMPVC++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS
Sbjct 1348 NLREMLAHAEETRKLMPVCMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVAS 1407
Query 1434 LINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSS 1493
+I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSS
Sbjct 1408 IITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAIVSVSSPDAVTTYNGYLTSS 1467
Query 1494 SKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVIT 1552
SKT E+HF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRG+K VY+T +P FHLDGEV+
Sbjct 1468 SKTSEDHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGEKIVYHTLESPVKFHLDGEVLP 1527
Query 1553 FDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNS 1612
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQ GPTYL+GADVTKIKPH +
Sbjct 1528 LDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQLGPTYLEGADVTKIKPHVN 1587
Query 1613 HEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADN 1672
HEGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADN
Sbjct 1588 HEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADN 1647
Query 1673 NCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETM 1732
NCYL++ LL LQQIE+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM
Sbjct 1648 NCYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETM 1707
Query 1733 SYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQ 1792
++L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+
Sbjct 1708 THLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKMGVSIPCVCGRD 1767
Query 1793 ATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGAL 1852
AT+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA
Sbjct 1768 ATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAH 1827
Query 1853 LTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPI 1912
LTK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPI
Sbjct 1828 LTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPI 1887
Query 1913 DLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDY 1972
DL+P QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY
Sbjct 1888 DLIPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDY 1947
Query 1973 KHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSED 2032
+HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1948 RHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVED 2007
Query 2033 AQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGH 2092
QGMDNLACE +P EEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+ H
Sbjct 2008 TQGMDNLACESQQPTPEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELDH 2067
Query 2093 TDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVST 2152
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + T
Sbjct 2068 EDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWGKILAYVKPFLGQAAVT 2127
Query 2153 TTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLE 2212
T+N R + R+ NYMPY TLL QLCTFT+STNSRI+AS+PTTIAKN+V+ + + CL+
Sbjct 2128 TSNCAKRLVQRMFNNYMPYVLTLLFQLCTFTKSTNSRIRASLPTTIAKNSVRGIVRLCLD 2187
Query 2213 ASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLN 2272
A NY+KSP FSKL I +W LLLS+CLGSLIY TAALGVL+SN G PSYC+G RE YLN
Sbjct 2188 AGINYVKSPKFSKLFTIAMWLLLLSICLGSLIYVTAALGVLLSNFGAPSYCSGVRESYLN 2247
Query 2273 STNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYI 2332
S+NVT +C GS PCSVCLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEWF AY+
Sbjct 2248 SSNVTTMDFCEGSFPCSVCLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWFFAYM 2307
Query 2333 LFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYY 2392
LFT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY
Sbjct 2308 LFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYY 2367
Query 2393 VWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNC 2452
+WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC
Sbjct 2368 IWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNC 2427
Query 2453 VNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKT 2512
+NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSY+VDSV VKNG++HLYFDKAGQKT
Sbjct 2428 LNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAGQKT 2487
Query 2513 YERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLL 2572
YERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES+AKSASVYYSQLMCQPILLL
Sbjct 2488 YERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPILLL 2547
Query 2573 DQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLST 2632
DQALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLST
Sbjct 2548 DQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLST 2607
Query 2633 FISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACI 2692
F+SA+RQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACI
Sbjct 2608 FVSASRQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACI 2667
Query 2693 DCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVN 2752
DC+ARHINAQVA+SHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVN
Sbjct 2668 DCNARHINAQVARSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVN 2727
Query 2753 VVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAI 2812
V+TTKI+LKGGKIV+ W K ++K TL+ + A + Y++ PVH++S H +++EIIGYKAI
Sbjct 2728 VITTKISLKGGKIVSTWFKIMLKATLLCVLAALVCYIVMPVHILSVHGGYTNEIIGYKAI 2787
Query 2813 DGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGT 2872
GVTRDI STD CFANKHA FD+WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT
Sbjct 2788 QDGVTRDIVSTDDCFANKHAGFDSWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGT 2847
Query 2873 ILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPY 2932
+LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DF+TSACVLAAECTIFKDA GKPVPY
Sbjct 2848 VLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFSTSACVLAAECTIFKDAMGKPVPY 2907
Query 2933 CYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERS 2992
CYDTN+LEGS++Y LRPDTRYVLMDGSIIQFPN YLEGSVRVVTTFD+EYCRHGTCERS
Sbjct 2908 CYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNAYLEGSVRVVTTFDAEYCRHGTCERS 2967
Query 2993 EAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGI 3052
EAG+C+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI
Sbjct 2968 EAGICLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGI 3027
Query 3053 VAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYL 3112
+AI+VTC AYYFM+FRRAFGEY+HVVA N LFLMSFT+LCL P YSFLPGVYSV YLYL
Sbjct 3028 IAILVTCAAYYFMKFRRAFGEYNHVVAANAPLFLMSFTILCLAPAYSFLPGVYSVFYLYL 3087
Query 3113 TFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSF 3172
TFY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KHF+WFF+NYL++RVVFNGV+F
Sbjct 3088 TFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHFHWFFNNYLRKRVVFNGVTF 3147
Query 3173 STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACC 3232
STFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACC
Sbjct 3148 STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACC 3207
Query 3233 HLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG 3292
HLAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG
Sbjct 3208 HLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG 3267
Query 3293 LWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKL 3352
LWLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+L
Sbjct 3268 LWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRL 3327
Query 3353 KVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVG 3412
KVDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVG
Sbjct 3328 KVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVG 3387
Query 3413 FNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLY 3472
FNIDYDCVSFCYMHHMELPT VHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLY
Sbjct 3388 FNIDYDCVSFCYMHHMELPTEVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLY 3447
Query 3473 AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLK 3532
AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LK
Sbjct 3448 AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALK 3507
Query 3533 ELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLL 3592
ELLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ KR +KGTHHW+LLT LTSLL
Sbjct 3508 ELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKRIVKGTHHWMLLTFLTSLL 3567
Query 3593 VLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNM 3652
+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNM
Sbjct 3568 ILVQSTQWSLFFFVYENAFLPFTLGIMAVAACAMLLVKHKHAFLCLFLLPSLATVAYFNM 3627
Query 3653 VYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLM 3712
VYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL+LMTARTVYDD ARRVWTLM
Sbjct 3628 VYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVWTLM 3687
Query 3713 NVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFIT 3772
NV+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FIT
Sbjct 3688 NVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFIT 3747
Query 3773 GNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK 3832
GNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK
Sbjct 3748 GNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK 3807
Query 3833 NSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV 3892
+SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV
Sbjct 3808 SSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV 3867
Query 3893 QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP 3952
QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP
Sbjct 3868 QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP 3927
Query 3953 SYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQM 4012
SYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR+AAMQRKLEKMADQAMTQM
Sbjct 3928 SYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRNAAMQRKLEKMADQAMTQM 3987
Query 4013 YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV 4072
YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV
Sbjct 3988 YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV 4047
Query 4073 VIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALR 4132
V+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+M+NS NLAWPLIVTALR
Sbjct 4048 VVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMENSSNLAWPLIVTALR 4107
Query 4133 ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLK 4192
ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLK
Sbjct 4108 ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLK 4167
Query 4193 WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRL 4252
WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL+FIKGLNNLNRGMVLGSLAATVRL
Sbjct 4168 WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLHFIKGLNNLNRGMVLGSLAATVRL 4227
Query 4253 QAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP 4312
QAGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP
Sbjct 4228 QAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP 4287
Query 4313 EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTV 4372
EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTV
Sbjct 4288 EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTV 4347
Query 4373 CGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYND 4432
CGMWKGYGCSCDQLREPM+QSADA +FLNRVCGVSAARLTPCGTG STDVVYRAFDIYN+
Sbjct 4348 CGMWKGYGCSCDQLREPMMQSADASTFLNRVCGVSAARLTPCGTGISTDVVYRAFDIYNE 4407
Query 4433 KVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHD 4492
KVAGFAKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+KDCPAVA HD
Sbjct 4408 KVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHD 4467
Query 4493 FFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKK 4552
FFKFR+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKK
Sbjct 4468 FFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKK 4527
Query 4553 DWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFG 4612
DWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWYDFG
Sbjct 4528 DWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFG 4587
Query 4613 DFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERL 4672
DF+Q PG GVP+VDSYYSLLMPILTLTRAL AESH+D DL KP IKWDLLKYDFT ERL
Sbjct 4588 DFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTAERL 4647
Query 4673 KLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPF 4732
LFDRYFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPF
Sbjct 4648 CLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPF 4707
Query 4733 VVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAA 4792
VVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAA
Sbjct 4708 VVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAA 4767
Query 4793 LTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNL 4852
LTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNL
Sbjct 4768 LTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNL 4827
Query 4853 PTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMS 4912
PTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMS
Sbjct 4828 PTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMS 4887
Query 4913 YEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIA 4972
YEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIA
Sbjct 4888 YEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIA 4947
Query 4973 ATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLAR 5032
ATRGATVVIGTSKFYGGWHNMLKTVYSDVE PHLMGWDYPKCDRAMPNMLRIMASLVLAR
Sbjct 4948 ATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLAR 5007
Query 5033 KHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAV 5092
KH+TCC+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAV
Sbjct 5008 KHSTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAV 5067
Query 5093 TANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSD 5152
TANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV EFYAYLRKHFSMMILSD
Sbjct 5068 TANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVGEFYAYLRKHFSMMILSD 5127
Query 5153 DAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLV 5212
DAVVC+NS YA+QGLVASIKNFK+VLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLV
Sbjct 5128 DAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLV 5187
Query 5213 KQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADV 5272
KQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADV
Sbjct 5188 KQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADV 5247
Query 5273 FHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLC 5332
FHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLC
Sbjct 5248 FHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLC 5307
Query 5333 NSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGM 5392
NSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGM
Sbjct 5308 NSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGM 5367
Query 5393 SYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTE 5452
SYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTE
Sbjct 5368 SYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTE 5427
Query 5453 RLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVT 5512
RLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVT
Sbjct 5428 RLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVT 5487
Query 5513 KNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVR 5572
KNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLN+GDYFVLTSHTVMPLSAPTLVPQEHYVR
Sbjct 5488 KNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNIGDYFVLTSHTVMPLSAPTLVPQEHYVR 5547
Query 5573 ITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTA 5632
ITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTA
Sbjct 5548 ITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTA 5607
Query 5633 CSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTA 5692
CSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTA
Sbjct 5608 CSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTA 5667
Query 5693 DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRL 5752
DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRL
Sbjct 5668 DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRL 5727
Query 5753 MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAI 5812
MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHK+KSAQCFKMFYKGVITHDVSSAI
Sbjct 5728 MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKEKSAQCFKMFYKGVITHDVSSAI 5787
Query 5813 NRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQ 5872
NRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQ
Sbjct 5788 NRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQ 5847
Query 5873 TTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGL 5932
TTETAHSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLE+PRRNVATLQAENVTGL
Sbjct 5848 TTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEVPRRNVATLQAENVTGL 5907
Query 5933 FKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVN 5992
FKDCSK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVN
Sbjct 5908 FKDCSKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVN 5967
Query 5993 GYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDT 6052
GYPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVA+PTGYVDT
Sbjct 5968 GYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAIPTGYVDT 6027
Query 6053 PNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWA 6112
NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFVLWA
Sbjct 6028 ENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWA 6087
Query 6113 HGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQW 6172
HGFELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPFMIDVQQW
Sbjct 6088 HGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQW 6147
Query 6173 GFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINA 6232
GFTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDELKIN+
Sbjct 6148 GFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELKINS 6207
Query 6233 ACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELF 6292
ACRKVQHMVVK+ALLADKFPVLHDIGNPKAIKCVPQA+VEWKFYDAQPCSDKAYKIEELF
Sbjct 6208 ACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELF 6267
Query 6293 YSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFH 6352
YSYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKHAFH
Sbjct 6268 YSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFH 6327
Query 6353 TPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHH 6412
TPAFDKSAF NLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHH
Sbjct 6328 TPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHH 6387
Query 6413 ANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQG 6472
ANEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQSLENVA+NVVNKGHFDGQ G
Sbjct 6388 ANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGQAG 6447
Query 6473 EVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIA 6532
E PVSIINN VYTKVDG DVE+FENKTTLPVNVAFELWAKRNIK VPE+KILNNLGVDIA
Sbjct 6448 ETPVSIINNAVYTKVDGFDVEIFENKTTLPVNVAFELWAKRNIKSVPEIKILNNLGVDIA 6507
Query 6533 ANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNG 6592
ANTVIWD+KR+AP H+STIGVC+MTDIAKKPTE+ C+ LTV FDGRV+GQVDLFRNARNG
Sbjct 6508 ANTVIWDHKREAPVHMSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNG 6567
Query 6593 VLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNL 6652
VLITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQSR+L
Sbjct 6568 VLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDL 6627
Query 6653 QEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKE 6712
++FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR ++
Sbjct 6628 EDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSRD 6687
Query 6713 SPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKV 6772
SP +LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKV
Sbjct 6688 SPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKV 6747
Query 6773 TIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSA 6832
TIDY EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG++A
Sbjct 6748 TIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENA 6807
Query 6833 TLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTL 6892
+PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTL
Sbjct 6808 VIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTL 6867
Query 6893 LVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYIC 6952
LVDSDLNDFVSDADSTLIGDCATVHTANKWDLI+SDMYDPK K+VTKENDSKEGFFTY+C
Sbjct 6868 LVDSDLNDFVSDADSTLIGDCATVHTANKWDLIVSDMYDPKAKHVTKENDSKEGFFTYLC 6927
Query 6953 GFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGK 7012
GFI+QKLALGGSVA+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NYLGK
Sbjct 6928 GFIKQKLALGGSVAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGVNYLGK 6987
Query 7013 PREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSL 7072
P+EQIDGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI SL
Sbjct 6988 PKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSL 7047
Query 7073 LSKGRLIIRENNRVVISSDVLVNN 7096
L KGRLIIRENNRVV+SSD+LVNN
Sbjct 7048 LEKGRLIIRENNRVVVSSDILVNN 7071
>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079
Score = 12917 bits (33522), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 6093/7107 (86%), Positives = 6568/7107 (92%), Gaps = 39/7107 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESL G +EKTHVQLSLPVLQVRDVLVRGFGDSVEE L+EAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLALGVSEKTHVQLSLPVLQVRDVLVRGFGDSVEEALAEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA+ HG+ +VELVAEL+GIQYGRSG TLGVLVPHVGE PVAYR
Sbjct 61 LPQLEQPYVFIKRSDAQGTNHGYKVVELVAELDGIQYGRSGTTLGVLVPHVGETPVAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLG ELGTDP ED+++NWNTKH GV REL+RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGVELGTDPIEDYEQNWNTKHGGGVLRELIRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A+TRYVDNNFCGPDGYPLECIKDLLARAGK+ CTLSEQLD+I++KRGVYCCREHEHEI W
Sbjct 181 AFTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERSEKSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSEKSYERQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + EVGPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PANAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIG +HTG+ G+ E LN++L+EIL +++VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASANIGASHTGITGDNVETLNEDLMEILNRDRVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SAST AFV+TVKGLDYK FK IVESCGNFKVT+G+AKKGAWNIG++KSIL+PLY F S+A
Sbjct 481 SASTCAFVDTVKGLDYKTFKDIVESCGNFKVTRGRAKKGAWNIGQEKSILTPLYGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIF+R L+TA +S+ LQ+AAITILDGIS+ SLRLIDAM++TSDL TN+++VMAY
Sbjct 541 AGVIRSIFTRALDTANHSIPDLQRAAITILDGISEQSLRLIDAMVYTSDLLTNSVIVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ +QWL+N+ GT +KLKPV W+E K G+EFLRD WEI+KF+ T +IV
Sbjct 601 VTGGLVQQITQWLSNMLGTTVDKLKPVFTWVEAKLSAGIEFLRDAWEILKFLVTGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + +KE V+ F ++NK L +C D +II GAKL+ LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNLKECVKAFLDVLNKALEMCIDQVIIAGAKLRTLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPL+APKE+ F EG++ T +EEVVLK G+L+ LE P ++G
Sbjct 721 IRGKEQLQLLMPLRAPKEVTFFEGDSHDTVFTSEEVVLKNGELEALETPVDSFTNGAVIG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVC+NGLMLLE+KD E+YCAL+P ++ TNN F+LKGGAP K VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCVNGLMLLELKDKEQYCALSPGLLATNNVFSLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 KITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ--YEYGTEDDYQG 957
WS+AT+YLFD++GE KL+S MYCSFYPPDE+E+ + E+EE P +EYGTEDDY+G
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCEEYEDEEEIPEETCEHEYGTEDDYKG 960
Query 958 KPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELT 1017
PLEFGA++ + QQ +++ + + E
Sbjct 961 LPLEFGAST----------------EIQQVDEEEEEDWLEEAIAAKPEPEPL-------- 996
Query 1018 PVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
VN F+GYLKLTDNV IK DIV+EA+ KPTV+VNAANV+LKHGGGVAGALNK
Sbjct 997 ---PEEPVNQFTGYLKLTDNVAIKCVDIVKEAQHAKPTVIVNAANVHLKHGGGVAGALNK 1053
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
ATN AMQ ESDDYI NGPL VGGSC+LSGHNLAK C+HVVGPN+N GED+QLLK+AY N
Sbjct 1054 ATNGAMQQESDDYIKKNGPLTVGGSCLLSGHNLAKKCMHVVGPNLNAGEDVQLLKAAYAN 1113
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK 1197
FN +VLLAPLLSAGIFGA P+ SL++CV+TVRT VY AV D++LYD +V +L+ K
Sbjct 1114 FNSQDVLLAPLLSAGIFGAKPLQSLKMCVETVRTQVYFAVNDQDLYDHVVLGYLDSLKPK 1173
Query 1198 QVE---QKIAEIPKEEVKPFITESKPSVEQ----RKQDDKKIKACVEEVTTTLEETKFLT 1250
VE Q+ E+ ++ +T+ +E+ K D K KA +EEV T+LEETKFLT
Sbjct 1174 -VETPTQENLELKEQPAVETLTQENLELEELPVIEKPVDVKFKARIEEVNTSLEETKFLT 1232
Query 1251 ENLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTT 1310
LLL+ DING L+ DS ++ D+ FL+KDAPYIVGDV+ G +T V+IP KKAGGTT
Sbjct 1233 SRLLLFADINGKLYQDSQNMLRGEDMFFLEKDAPYIVGDVISSGDITCVIIPAKKAGGTT 1292
Query 1311 EMLAKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGT 1370
EMLAKAL+KVP YITTYPGQG GYT+EEAKT L+KCKS FY+LPS N+K+EILGT
Sbjct 1293 EMLAKALKKVPVSEYITTYPGQGCAGYTLEEAKTALRKCKSVFYVLPSKTPNDKEEILGT 1352
Query 1371 VSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTT 1430
VSWNLREMLAHAEETRKLM +C++ KA++STI R+YKGIK+QEG+VDYG RF+FYTSK
Sbjct 1353 VSWNLREMLAHAEETRKLMLICMDVKALMSTIHRRYKGIKVQEGIVDYGVRFFFYTSKEP 1412
Query 1431 VASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYL 1490
VAS+I LN LNE LVTMP+GYVTHGLNLEEAAR MRSLK PA VSVSSPDAVT YNGYL
Sbjct 1413 VASIITKLNLLNEPLVTMPIGYVTHGLNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYL 1472
Query 1491 TSSSKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGE 1549
TSSSKT EEHFIET+SLAG Y+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGE
Sbjct 1473 TSSSKTSEEHFIETVSLAGMYRDWSYSGQRTELGVEFLKRGDKVVYHTVGSPIQFHLDGE 1532
Query 1550 VITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKP 1609
V+ D LK+LLSLREVRTIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKP
Sbjct 1533 VLLLDKLKSLLSLREVRTIKVFTTVDNTNLHTQIVDMSMTYGQQFGPTYLDGADVTKIKP 1592
Query 1610 HNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKW 1669
H HEGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQ+ GLTSIKW
Sbjct 1593 HAKHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQIGGLTSIKW 1652
Query 1670 ADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVR 1729
ADNNCYL++ LL LQQIE+KFN PALQ+AYYRARAG+AANFCALILAY N+TVGELGDVR
Sbjct 1653 ADNNCYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAYSNRTVGELGDVR 1712
Query 1730 ETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTC 1789
ETM++L QHANL+S KRVLNVVCKTCGQ+ TTL GVEAVMYMGTLSYE+ K GV IPC C
Sbjct 1713 ETMTHLLQHANLESAKRVLNVVCKTCGQKSTTLTGVEAVMYMGTLSYEELKTGVTIPCIC 1772
Query 1790 GKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCID 1849
G+ AT+YLVQQES FVMMSAPP++Y L+ G F CA+EYTG+YQCGHY H+T KETLY ID
Sbjct 1773 GRDATQYLVQQESSFVMMSAPPSEYTLQQGAFLCANEYTGSYQCGHYTHVTVKETLYRID 1832
Query 1850 GALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTE 1909
GA LTK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV+ TEI PKLD YYKKDN+Y+TE
Sbjct 1833 GAYLTKMSEYKGPVTDVFYKEISYTTTIKPVSYKLDGVIYTEIQPKLDEYYKKDNAYYTE 1892
Query 1910 QPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVA 1969
QPIDLVP QP PNASFDNFK C N KFADDLNQ+TG+KKPASREL VTFFPDLNGDVVA
Sbjct 1893 QPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFKKPASRELSVTFFPDLNGDVVA 1952
Query 1970 IDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLK 2029
IDY+HY+ SFKKGAKLLHKPI+WH+N TNK TYKPNTWC+RCLWSTKPVETSNSF+VL+
Sbjct 1953 IDYRHYSASFKKGAKLLHKPIIWHINQTTNKTTYKPNTWCLRCLWSTKPVETSNSFEVLE 2012
Query 2030 SEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEE 2089
ED QGMDNLACE P SEEVVENPTIQK+V+EC+VKT EVVG++ILKP+ +K+T+E
Sbjct 2013 VEDTQGMDNLACESQTPTSEEVVENPTIQKEVIECDVKTIEVVGNVILKPSEEGVKVTQE 2072
Query 2090 VGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKV 2149
+GH DLMAAYV+ +S+TIKKPNELS LGL+TLATHG AA+NSVPW I Y KPFL +
Sbjct 2073 LGHEDLMAAYVEETSITIKKPNELSLALGLRTLATHGAAAINSVPWSKILAYVKPFLGQA 2132
Query 2150 VSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKF 2209
TTTN + RC+ RV NYMPY TLL QLCTFTRSTNSRI+AS+PTTIAKN+VKSV K
Sbjct 2133 AVTTTNCIKRCVQRVFNNYMPYVITLLFQLCTFTRSTNSRIRASLPTTIAKNSVKSVAKL 2192
Query 2210 CLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREG 2269
CL+ NY+KSP FSKL I +W LLLS+CLGSLIY TAA GVL+SNLG+PSYC G RE
Sbjct 2193 CLDVCINYVKSPKFSKLFTIAMWLLLLSICLGSLIYVTAAFGVLLSNLGIPSYCDGVRES 2252
Query 2270 YLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFL 2329
Y+NS+NVT +C GS CSVCL+GLDSLD+YP+LETIQ+TISS+K DLT+ GL AEWFL
Sbjct 2253 YVNSSNVTTMDFCEGSFLCSVCLNGLDSLDSYPALETIQVTISSYKLDLTSLGLAAEWFL 2312
Query 2330 AYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFAS 2389
AY+LFT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFA
Sbjct 2313 AYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFAF 2372
Query 2390 FYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHN 2449
YYVWKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HN
Sbjct 2373 CYYVWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKAHN 2432
Query 2450 WNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAG 2509
WNC+NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSY+VDSV VKNG++HLYFDKAG
Sbjct 2433 WNCLNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAG 2492
Query 2510 QKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPI 2569
QKTYERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES+AKSASVYYSQLMCQPI
Sbjct 2493 QKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPI 2552
Query 2570 LLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNV 2629
LLLDQALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD V
Sbjct 2553 LLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGV 2612
Query 2630 LSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLG 2689
LSTF+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLG
Sbjct 2613 LSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLG 2672
Query 2690 ACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQ 2749
ACIDC+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQ
Sbjct 2673 ACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQ 2732
Query 2750 VVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGY 2809
VVN +TTKI+LKGGKIV+ W K ++K TL+ + A Y+I PVH +S H +++EIIGY
Sbjct 2733 VVNAITTKISLKGGKIVSTWFKLMLKATLLCVLAALFCYIIMPVHSLSVHDGYTNEIIGY 2792
Query 2810 KAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGL 2869
KAI GVTRDI +TD CFANKHA FD+WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGL
Sbjct 2793 KAIQDGVTRDIMATDDCFANKHAGFDSWFSQRGGSYRNDKSCPVVAAIITREIGFIVPGL 2852
Query 2870 PGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKP 2929
PGT+LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKP
Sbjct 2853 PGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKP 2912
Query 2930 VPYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTC 2989
VPYCYDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTC
Sbjct 2913 VPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTC 2972
Query 2990 ERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVA 3049
ERSEAGVC+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VA
Sbjct 2973 ERSEAGVCLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVA 3032
Query 3050 GGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIY 3109
GGI+AI+VTC AYYFM+FRRAFGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYS+ Y
Sbjct 3033 GGIIAILVTCAAYYFMKFRRAFGEYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFY 3092
Query 3110 LYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNG 3169
LYLTFY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNG
Sbjct 3093 LYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNG 3152
Query 3170 VSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREA 3229
V+FSTFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREA
Sbjct 3153 VTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREA 3212
Query 3230 ACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT 3289
ACCHLAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT
Sbjct 3213 ACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT 3272
Query 3290 LNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCV 3349
LNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+
Sbjct 3273 LNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCL 3332
Query 3350 LKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCG 3409
L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN+TIKGSFLNGSCG
Sbjct 3333 LRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNYTIKGSFLNGSCG 3392
Query 3410 SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLA 3469
SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLA
Sbjct 3393 SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLA 3452
Query 3470 WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA 3529
WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA
Sbjct 3453 WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA 3512
Query 3530 SLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILT 3589
+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LT
Sbjct 3513 ALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLT 3572
Query 3590 SLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAY 3649
SLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAY
Sbjct 3573 SLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAY 3632
Query 3650 FNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVW 3709
FNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL+LMTARTVYDD ARRVW
Sbjct 3633 FNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVW 3692
Query 3710 TLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIF 3769
TLMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+
Sbjct 3693 TLMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLL 3752
Query 3770 FITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL 3829
FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL
Sbjct 3753 FITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL 3812
Query 3830 PPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA 3889
PPK+SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA
Sbjct 3813 PPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA 3872
Query 3890 QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFS 3949
QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFS
Sbjct 3873 QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFS 3932
Query 3950 SLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM 4009
SLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM
Sbjct 3933 SLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM 3992
Query 4010 TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK 4069
TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK
Sbjct 3993 TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK 4052
Query 4070 LMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVT 4129
LMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNS NLAWPLIVT
Sbjct 4053 LMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSQNLAWPLIVT 4112
Query 4130 ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQ 4189
ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD Q
Sbjct 4113 ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQ 4172
Query 4190 DLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAAT 4249
DLKWARFPKSDGTGTIYTELEPPCRFVTDTP+GPKVKYLYFIKGLNNLNRGMVLGSLAAT
Sbjct 4173 DLKWARFPKSDGTGTIYTELEPPCRFVTDTPRGPKVKYLYFIKGLNNLNRGMVLGSLAAT 4232
Query 4250 VRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT 4309
VRLQAGNATEVPANS VLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT
Sbjct 4233 VRLQAGNATEVPANSAVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT 4292
Query 4310 VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIP TCANDPVGFTLKNTV
Sbjct 4293 VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPATCANDPVGFTLKNTV 4352
Query 4370 CTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDI 4429
CTVCG WKGYGCSCDQLREPM+QSADA +FLNRVCGVSAARLTPCGTGTSTDVVYRAFDI
Sbjct 4353 CTVCGTWKGYGCSCDQLREPMMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDI 4412
Query 4430 YNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVA 4489
YN++VAGFAKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+K+CPAVA
Sbjct 4413 YNERVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKECPAVA 4472
Query 4490 KHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYF 4549
HDFFKFR+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYF
Sbjct 4473 VHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYF 4532
Query 4550 NKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWY 4609
NKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWY
Sbjct 4533 NKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWY 4592
Query 4610 DFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTE 4669
DFGDF+Q PG GVP+VDSYYSLLMPILTLT+AL AESH+D DL KP IKWDLLKYDFTE
Sbjct 4593 DFGDFVQVAPGCGVPIVDSYYSLLMPILTLTKALAAESHMDADLAKPLIKWDLLKYDFTE 4652
Query 4670 ERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDG 4729
ERL LFDRYFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDG
Sbjct 4653 ERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDG 4712
Query 4730 VPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFS 4789
VPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFS
Sbjct 4713 VPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFS 4772
Query 4790 VAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYR 4849
VAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYR
Sbjct 4773 VAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYR 4832
Query 4850 YNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYD 4909
YNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYD
Sbjct 4833 YNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYD 4892
Query 4910 SMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLK 4969
SMSYEDQD LFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLK
Sbjct 4893 SMSYEDQDVLFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLK 4952
Query 4970 SIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLV 5029
SIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE PHLMGWDYPKCDRAMPNMLRIMASLV
Sbjct 4953 SIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLV 5012
Query 5030 LARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNIC 5089
LARKH+TCC+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNIC
Sbjct 5013 LARKHSTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNIC 5072
Query 5090 QAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMI 5149
QAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV+EFYAYLRKHFSMMI
Sbjct 5073 QAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMI 5132
Query 5150 LSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHT 5209
LSDDAVVC+NS YA+QGLVASIKNFK+V YYQNNVFMSEAKCWTETDLTKGPHEFCSQHT
Sbjct 5133 LSDDAVVCYNSNYAAQGLVASIKNFKAVHYYQNNVFMSEAKCWTETDLTKGPHEFCSQHT 5192
Query 5210 MLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEY 5269
MLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEY
Sbjct 5193 MLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEY 5252
Query 5270 ADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGAC 5329
ADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGAC
Sbjct 5253 ADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGAC 5312
Query 5330 VLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYL 5389
VLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYL
Sbjct 5313 VLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYL 5372
Query 5390 GGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANT 5449
GGMSYYCK HKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANT
Sbjct 5373 GGMSYYCKLHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANT 5432
Query 5450 CTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGY 5509
CTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGY
Sbjct 5433 CTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGY 5492
Query 5510 RVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEH 5569
RVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEH
Sbjct 5493 RVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEH 5552
Query 5570 YVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIV 5629
YVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIV
Sbjct 5553 YVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIV 5612
Query 5630 YTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPE 5689
YTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPE
Sbjct 5613 YTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPE 5672
Query 5690 TTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV 5749
TTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV
Sbjct 5673 TTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV 5732
Query 5750 CRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVS 5809
CRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHK+KSAQCFKMFYKGVITHDVS
Sbjct 5733 CRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKEKSAQCFKMFYKGVITHDVS 5792
Query 5810 SAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVI 5869
SAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVI
Sbjct 5793 SAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVI 5852
Query 5870 FTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENV 5929
FTQTTETAHSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLE+PRRNVATLQAENV
Sbjct 5853 FTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEVPRRNVATLQAENV 5912
Query 5930 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNY 5989
TGLFKDCSK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNY
Sbjct 5913 TGLFKDCSKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNY 5972
Query 5990 QVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGY 6049
QVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAVPTGY
Sbjct 5973 QVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGY 6032
Query 6050 VDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFV 6109
VDT NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFV
Sbjct 6033 VDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFV 6092
Query 6110 LWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDV 6169
LWAHGFELTSMKYFVKIGPERTCCLCDRRATCFST+SDTYACW+HS+GFDYVYNPFMIDV
Sbjct 6093 LWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTSSDTYACWNHSVGFDYVYNPFMIDV 6152
Query 6170 QQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELK 6229
QQWGFTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDELK
Sbjct 6153 QQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELK 6212
Query 6230 INAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIE 6289
INAACRKVQHMVVK+ALLADKF VLHDIGNPKAIKCVPQA+V+WKFYDAQPCSDKAYKIE
Sbjct 6213 INAACRKVQHMVVKSALLADKFSVLHDIGNPKAIKCVPQAEVDWKFYDAQPCSDKAYKIE 6272
Query 6290 ELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKH 6349
ELFYSYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKH
Sbjct 6273 ELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKH 6332
Query 6350 AFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVC 6409
AFHTPAFDKSAF LKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVC
Sbjct 6333 AFHTPAFDKSAFTYLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVC 6392
Query 6410 RHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDG 6469
R HANEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQSLENVA+NVVNKGHFDG
Sbjct 6393 RRHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDG 6452
Query 6470 QQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGV 6529
Q GE PVSIINN VYTKVDG DVE+FENKTTLPVNVAFELWAKRNIKPVPE+KILNNLGV
Sbjct 6453 QIGEAPVSIINNAVYTKVDGNDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGV 6512
Query 6530 DIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNA 6589
DIAANTVIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ LTV FDGRV+GQVDLFRNA
Sbjct 6513 DIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNA 6572
Query 6590 RNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQS 6649
RNGVLITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQS
Sbjct 6573 RNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQS 6632
Query 6650 RNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKR 6709
R+L++FKPRS+ME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR
Sbjct 6633 RDLEDFKPRSKMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKR 6692
Query 6710 FKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKV 6769
++SP +LEDFIP DSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV+SKV
Sbjct 6693 SQDSPLKLEDFIPTDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKV 6752
Query 6770 VKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYG 6829
VKVTIDY EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG
Sbjct 6753 VKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYG 6812
Query 6830 DSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPT 6889
++A +PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPT
Sbjct 6813 ENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPT 6872
Query 6890 GTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFT 6949
G LLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTK+VTKENDSKEGFFT
Sbjct 6873 GALLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKHVTKENDSKEGFFT 6932
Query 6950 YICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNY 7009
Y+CGFI+QKLALGGSVA+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NY
Sbjct 6933 YLCGFIKQKLALGGSVAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGVNY 6992
Query 7010 LGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMI 7069
LGK REQIDGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI
Sbjct 6993 LGKLREQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMI 7052
Query 7070 LSLLSKGRLIIRENNRVVISSDVLVNN 7096
SLL GRLIIRENNRVV+SSD+LVNN
Sbjct 7053 YSLLENGRLIIRENNRVVVSSDILVNN 7079
>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067
Score = 12908 bits (33499), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 6092/7102 (86%), Positives = 6576/7102 (93%), Gaps = 41/7102 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA + HGH +VELVAEL+GIQ+GRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAELDGIQFGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHS+G DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
TRYVDNNFCGPDGYPLECIKD LARAGK+ CTLSEQLD+I++KRGVYCCREHEHEI W
Sbjct 181 VVTRYVDNNFCGPDGYPLECIKDFLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERSEKSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSEKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + EVGPEHS+A+YHN S ++T LRKGGRT FGGCVFSYVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFSYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIG NHTG+ GE E LN++LLEIL +E+VNINIVGDF+ NEE+AIILASF
Sbjct 421 AYWVPRASANIGANHTGITGENVETLNEDLLEILNRERVNINIVGDFRFNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SAS SAF+ETVKGLDYK+FK IVESCGN+KVT GK GAWNIG+Q+SIL+PL F S+A
Sbjct 481 SASPSAFIETVKGLDYKSFKVIVESCGNYKVTNGKPVTGAWNIGQQRSILTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIFSRTL+ A +S+ LQ+AA+T LDGIS+ SLRL+DAM++TSDL TN++VVMAY
Sbjct 541 AGVIRSIFSRTLDAANHSILDLQRAAVTTLDGISEQSLRLVDAMVYTSDLLTNSVVVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ T QWL+N+ GT +KLKPV W+E K GVEFLRD WEI+KF+ T +++
Sbjct 601 VTGGLVQQTMQWLSNMLGTAVDKLKPVFTWVEAKLSAGVEFLRDAWEILKFLITGVFDVI 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI IKE V+ F +VNK L +C D + I G KL+ALNLGE F+ S+GLYR+C
Sbjct 661 KGQIQVATDNIKECVKIFLGVVNKALEMCLDQVTIAGTKLRALNLGEVFIAQSRGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG+ T + +EEVVLK+G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDAHDTVLTSEEVVLKSGELEALETPIDSFTSGAVVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVCINGLMLLE+++ E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCINGLMLLELENKEQYCALSPGLLATNNVFRLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELD R+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLTP+GIDLDE
Sbjct 841 KITFELDVRVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTPMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKP 959
WS+AT+YLFD++GE KL+S MYCSFYPPDE+E+ E E+ E + ++EYGTEDDY+G P
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCE--ECEDEEETCEHEYGTEDDYKGLP 958
Query 960 LEFGATSAALQ-PEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
LEFGA++ EEE+EEDWLDD + +
Sbjct 959 LEFGASTETPHVEEEEEEEDWLDDAIEAEPEPE--------------------------- 991
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
+ VN F GYLKLTDNV IK DIV+EA+ KPTV+VNAAN +LKHGGGVAGALNKA
Sbjct 992 PLPEEPVNQFVGYLKLTDNVAIKCIDIVKEAQSAKPTVIVNAANTHLKHGGGVAGALNKA 1051
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
TN AMQ ESD+YI NGPL VGGSC+LSGHNLA+ CLHVVGPN+N GED+QLLK AYENF
Sbjct 1052 TNGAMQNESDEYIRQNGPLTVGGSCLLSGHNLAEKCLHVVGPNLNAGEDVQLLKRAYENF 1111
Query 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
N +VLLAPLLSAGIFGA P+ SL++CV+ VRT VYLAV DK+LYD++V +L+ K
Sbjct 1112 NSQDVLLAPLLSAGIFGAKPLQSLKMCVEIVRTQVYLAVNDKSLYDQIVLDYLDSLKPK- 1170
Query 1199 VEQKIAEIPKEEVKPFITES---KPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL 1255
E P +E +P + E +P E+ KIKAC++EVTTTLEETKFLT LLL
Sbjct 1171 -----VESPNKEEEPKLEEPKAVQPVAEKPVDVKPKIKACIDEVTTTLEETKFLTNKLLL 1225
Query 1256 YIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAK 1315
+ DING L+ DS ++ D++FL+KDAPYIVGDV+ G +T V+IP KK+GGTTEMLA+
Sbjct 1226 FADINGKLYQDSQNMLRGEDMSFLEKDAPYIVGDVITSGDITCVIIPAKKSGGTTEMLAR 1285
Query 1316 ALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNL 1375
AL++VP YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS NEK+E+LGTVSWNL
Sbjct 1286 ALKEVPVAEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSETPNEKEEVLGTVSWNL 1345
Query 1376 REMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLI 1435
REMLAHAEETRKLMP+C++ +AI++TIQRKYKGIK+QEG+VDYG RF+FYTSK VAS+I
Sbjct 1346 REMLAHAEETRKLMPICLDVRAIMATIQRKYKGIKVQEGIVDYGVRFFFYTSKEPVASII 1405
Query 1436 NTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSK 1495
LN LNE LVTMP+GYVTHGLNLEEAAR MRSLK PA VSVSSPDAVTAYNGYLTSSSK
Sbjct 1406 TKLNSLNEPLVTMPIGYVTHGLNLEEAARCMRSLKAPAVVSVSSPDAVTAYNGYLTSSSK 1465
Query 1496 TPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTS-NPTTFHLDGEVITFD 1554
TPEE+F+ET SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T+ +P FHLDGEV+ D
Sbjct 1466 TPEEYFVETTSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTTGSPIEFHLDGEVLPLD 1525
Query 1555 NLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHE 1614
LK+LLSLREV+TIKVFTTVDN NLHT +VDMSMTYGQQFGPTYLDGADVTKIKPH +HE
Sbjct 1526 KLKSLLSLREVKTIKVFTTVDNTNLHTHIVDMSMTYGQQFGPTYLDGADVTKIKPHVNHE 1585
Query 1615 GKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNC 1674
GKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNNC
Sbjct 1586 GKTFFVLPSDDTLRSEAFEYYHTIDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNC 1645
Query 1675 YLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSY 1734
YL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM++
Sbjct 1646 YLSSVLLALQQVEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTH 1705
Query 1735 LFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQAT 1794
L QHANL+S KRVLNVVCK CGQ+ TTLKGVEAVMYMGTLSY++ K GV IPC CG+ AT
Sbjct 1706 LLQHANLESAKRVLNVVCKHCGQKTTTLKGVEAVMYMGTLSYDELKTGVSIPCVCGRNAT 1765
Query 1795 KYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLT 1854
+YLVQQES FVMMSAPPA+Y+L+ G F CA+EYTGNYQCGHY HIT+KETLY +DGA LT
Sbjct 1766 QYLVQQESSFVMMSAPPAEYKLQQGAFLCANEYTGNYQCGHYTHITAKETLYRVDGAHLT 1825
Query 1855 KSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL 1914
K SEYKGP+TDVFYKE SYTT IKPV+YKLDGV TEI+PKLD YYKK N+Y+TEQPIDL
Sbjct 1826 KMSEYKGPVTDVFYKETSYTTAIKPVSYKLDGVTYTEIEPKLDGYYKKGNAYYTEQPIDL 1885
Query 1915 VPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKH 1974
VP QP PNASFDNFK C N KFADDLNQ+TG+KKPASREL VTFFPDLNGDVVAIDY+H
Sbjct 1886 VPTQPMPNASFDNFKLTCSNTKFADDLNQMTGFKKPASRELTVTFFPDLNGDVVAIDYRH 1945
Query 1975 YTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQ 2034
Y+ SFKKGAKL+HKPI+WH+N TNK TYKPN WC+RCLWSTKPV+TSNSF+VL ED Q
Sbjct 1946 YSTSFKKGAKLVHKPILWHINQTTNKTTYKPNIWCLRCLWSTKPVDTSNSFEVLVVEDTQ 2005
Query 2035 GMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTD 2094
GMDNLACE SEEVVENPT+QK+++EC+VKTTEVVG++ILKP+ +K+T+E+GH D
Sbjct 2006 GMDNLACESQTTTSEEVVENPTVQKEIIECDVKTTEVVGNVILKPSEEGVKVTQELGHED 2065
Query 2095 LMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT 2154
LMAAYV+ +S+TIKKPNELS LGLKTLATHG AA+NSVPW I Y KPFL + T+
Sbjct 2066 LMAAYVEETSITIKKPNELSLALGLKTLATHGAAAINSVPWSKILAYVKPFLGQTAVITS 2125
Query 2155 NIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEAS 2214
N + +C+ RV +NYMPY TLL QLCTFT+STNSRIKAS+PTTIAKN+VKSV K CL+
Sbjct 2126 NCIKKCVQRVFSNYMPYVITLLFQLCTFTKSTNSRIKASLPTTIAKNSVKSVAKLCLDVC 2185
Query 2215 FNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNST 2274
NY+KSP FSKL I++W LLLS+CLGSL Y TA LGV +S+LG+PSYC G RE Y+NS+
Sbjct 2186 INYVKSPKFSKLFTIVMWLLLLSICLGSLTYVTAVLGVCLSSLGVPSYCDGVRELYINSS 2245
Query 2275 NVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILF 2334
NVT +C G PCSVCLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+LF
Sbjct 2246 NVTTMDFCQGYFPCSVCLSGLDSLDSYPALETIQVTISSYKLDLTFLGLAAEWLLAYMLF 2305
Query 2335 TRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVW 2394
T+FFY+LGL+AIMQ FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYYVW
Sbjct 2306 TKFFYLLGLSAIMQAFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYVW 2365
Query 2395 KSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVN 2454
KSYVH++DGC SSTCMMCYKRNRATRVECTTIVNGV+RSFYVYANGG+GFCK HNWNC+N
Sbjct 2366 KSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGVKRSFYVYANGGRGFCKAHNWNCLN 2425
Query 2455 CDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYE 2514
CDTFCAGSTFISDEVARDLSLQFKRPINPTDQS+Y+VDSVTVKNG++HLYFDKAGQKTYE
Sbjct 2426 CDTFCAGSTFISDEVARDLSLQFKRPINPTDQSAYVVDSVTVKNGALHLYFDKAGQKTYE 2485
Query 2515 RHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQ 2574
RH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES+AKSASVYYSQLMCQPILLLDQ
Sbjct 2486 RHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESAAKSASVYYSQLMCQPILLLDQ 2545
Query 2575 ALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFI 2634
ALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF+
Sbjct 2546 ALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFV 2605
Query 2635 SAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDC 2694
SAARQG VD+DV+TKDV+ECLKLSH SDIEVTGDSCNN+MLTYNKVENMTPRDLGACIDC
Sbjct 2606 SAARQGVVDTDVDTKDVIECLKLSHHSDIEVTGDSCNNFMLTYNKVENMTPRDLGACIDC 2665
Query 2695 SARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVV 2754
+ARHINAQVAKSHN++L+WNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV+
Sbjct 2666 NARHINAQVAKSHNVSLVWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVI 2725
Query 2755 TTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDG 2814
TTKI+LKGGK+V+ W K L+KVTL+ + A Y+I PVH +S H +++EIIGYKAI
Sbjct 2726 TTKISLKGGKVVSTWFKLLLKVTLLCVLAALFCYVIMPVHSLSVHDGYTNEIIGYKAIQD 2785
Query 2815 GVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTIL 2874
GVTRDI STD CFANKHA FD+WFSQRGGSY NDK CP++AA+ITRE+GF+VPGLPGT+L
Sbjct 2786 GVTRDIVSTDDCFANKHAGFDSWFSQRGGSYRNDKNCPVVAAIITREIGFIVPGLPGTVL 2845
Query 2875 RTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCY 2934
R NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYCY
Sbjct 2846 RALNGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCY 2905
Query 2935 DTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEA 2994
DTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2906 DTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEV 2965
Query 2995 GVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVA 3054
GVC+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+A
Sbjct 2966 GVCLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIA 3025
Query 3055 IVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTF 3114
I+VTC AYYFM+FRRAFGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYS+ YLYLTF
Sbjct 3026 ILVTCAAYYFMKFRRAFGEYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFYLYLTF 3085
Query 3115 YLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFST 3174
Y TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KHF+WFFSNYLK+RV+FNGV+FST
Sbjct 3086 YFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHFHWFFSNYLKKRVMFNGVTFST 3145
Query 3175 FEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL 3234
FEEAALCTFLLNKEMYL+LRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCHL
Sbjct 3146 FEEAALCTFLLNKEMYLRLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHL 3205
Query 3235 AKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW 3294
AKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW
Sbjct 3206 AKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW 3265
Query 3295 LDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKV 3354
LDD VYCPRHV+CT+EDMLNPNY+DLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LKV
Sbjct 3266 LDDTVYCPRHVVCTAEDMLNPNYDDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKV 3325
Query 3355 DTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFN 3414
DT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGFN
Sbjct 3326 DTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFN 3385
Query 3415 IDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAA 3474
IDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAA
Sbjct 3386 IDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAA 3445
Query 3475 VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKEL 3534
VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKEL
Sbjct 3446 VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKEL 3505
Query 3535 LQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVL 3594
LQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+L
Sbjct 3506 LQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLIL 3565
Query 3595 VQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVY 3654
VQSTQWSLFFF+YENAFLPFA+GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMVY
Sbjct 3566 VQSTQWSLFFFVYENAFLPFALGIMAVAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVY 3625
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNV 3714
MPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMNV
Sbjct 3626 MPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNV 3685
Query 3715 LTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGN 3774
+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITGN
Sbjct 3686 ITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGN 3745
Query 3775 TLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNS 3834
TLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+S
Sbjct 3746 TLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSS 3805
Query 3835 IDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQL 3894
IDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQL
Sbjct 3806 IDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQL 3865
Query 3895 HNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSY 3954
HNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSY
Sbjct 3866 HNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSY 3925
Query 3955 AAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYK 4014
AA+ATAQEAYEQAV+NGDSEVVLKKLKKSLNVAKSEFD DAAMQRKLEKMADQAMTQMYK
Sbjct 3926 AAYATAQEAYEQAVSNGDSEVVLKKLKKSLNVAKSEFDHDAAMQRKLEKMADQAMTQMYK 3985
Query 4015 QARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVI 4074
QARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV+
Sbjct 3986 QARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVV 4045
Query 4075 PDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN 4134
PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRAN
Sbjct 4046 PDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN 4105
Query 4135 SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN KGGRFVLALLSD QDLKWA
Sbjct 4106 SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNAKGGRFVLALLSDHQDLKWA 4165
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA
Sbjct 4166 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4225
Query 4255 GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA 4314
GNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA
Sbjct 4226 GNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA 4285
Query 4315 NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCG 4374
NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVCG
Sbjct 4286 NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCG 4345
Query 4375 MWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKV 4434
MWKGYGCSCDQLREPM+QSADA +FLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYN+KV
Sbjct 4346 MWKGYGCSCDQLREPMMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEKV 4405
Query 4435 AGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFF 4494
AGFAKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+K+CPAVA HDFF
Sbjct 4406 AGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLIKECPAVAVHDFF 4465
Query 4495 KFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDW 4554
KFR+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDD+YFNKKDW
Sbjct 4466 KFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDNYFNKKDW 4525
Query 4555 YDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDF 4614
YDFVENPD+LRVYANLGERVR+ALLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWYDFGDF
Sbjct 4526 YDFVENPDVLRVYANLGERVRRALLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDF 4585
Query 4615 IQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKL 4674
+Q PG GVP+VDSYYSLLMPILTLT+AL AESH+D DL KP +KWDLLKYDFTEERL L
Sbjct 4586 VQVAPGCGVPIVDSYYSLLMPILTLTKALAAESHMDADLAKPLVKWDLLKYDFTEERLCL 4645
Query 4675 FDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVV 4734
FDRYFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVV
Sbjct 4646 FDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVV 4705
Query 4735 STGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALT 4794
STGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALT
Sbjct 4706 STGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALT 4765
Query 4795 NNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPT 4854
NNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPT
Sbjct 4766 NNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPT 4825
Query 4855 MCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYE 4914
MCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYE
Sbjct 4826 MCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYE 4885
Query 4915 DQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAAT 4974
DQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAAT
Sbjct 4886 DQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAAT 4945
Query 4975 RGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKH 5034
RGATVVIGTSKFYGGWHNMLKTVYSDVE+PHLMGWDYPKCDRAMPNMLRIMASL+LARKH
Sbjct 4946 RGATVVIGTSKFYGGWHNMLKTVYSDVESPHLMGWDYPKCDRAMPNMLRIMASLILARKH 5005
Query 5035 TTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5094
+TCC+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTA
Sbjct 5006 STCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5065
Query 5095 NVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDA 5154
NVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV+EFYAYLRKHFSMMILSDDA
Sbjct 5066 NVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDA 5125
Query 5155 VVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQ 5214
VVC+NS YA+QGLVASIKNFK+VLYYQNNVFMSEAKCWTETDLT+GPHEFCSQHTMLVKQ
Sbjct 5126 VVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTRGPHEFCSQHTMLVKQ 5185
Query 5215 GDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFH 5274
GDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFH
Sbjct 5186 GDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFH 5245
Query 5275 LYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNS 5334
LYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNS
Sbjct 5246 LYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNS 5305
Query 5335 QTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSY 5394
QTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSY
Sbjct 5306 QTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSY 5365
Query 5395 YCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERL 5454
YCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERL
Sbjct 5366 YCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERL 5425
Query 5455 KLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKN 5514
KLFAAETLKATEETFKLSYGIATVREVLSDREL+LSWEVGKPRPPLNRNYVFTGYRVTKN
Sbjct 5426 KLFAAETLKATEETFKLSYGIATVREVLSDRELYLSWEVGKPRPPLNRNYVFTGYRVTKN 5485
Query 5515 SKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRIT 5574
SKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRIT
Sbjct 5486 SKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRIT 5545
Query 5575 GLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACS 5634
GLYPTLNIS+EFSSNVANYQK+GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACS
Sbjct 5546 GLYPTLNISNEFSSNVANYQKIGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACS 5605
Query 5635 HAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADI 5694
HAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADI
Sbjct 5606 HAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADI 5665
Query 5695 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK 5754
VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK
Sbjct 5666 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK 5725
Query 5755 TIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINR 5814
TIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHK+KSAQCFKM+YKGVITHDVSSAINR
Sbjct 5726 TIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKEKSAQCFKMYYKGVITHDVSSAINR 5785
Query 5815 PQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTT 5874
PQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTT
Sbjct 5786 PQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTT 5845
Query 5875 ETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFK 5934
ETAHSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLE+PRRNVATLQAENVTGLFK
Sbjct 5846 ETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEVPRRNVATLQAENVTGLFK 5905
Query 5935 DCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGY 5994
DCSK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGY
Sbjct 5906 DCSKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGY 5965
Query 5995 PNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPN 6054
PNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAVPTGYVDT N
Sbjct 5966 PNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTEN 6025
Query 6055 NTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHG 6114
+T+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFVLWAHG
Sbjct 6026 STEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHG 6085
Query 6115 FELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGF 6174
FELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPFMIDVQQWGF
Sbjct 6086 FELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGF 6145
Query 6175 TGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAAC 6234
TGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDELKINAAC
Sbjct 6146 TGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELKINAAC 6205
Query 6235 RKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYS 6294
RKVQHMVVK+ALLADKF VLHDIGNPKAI+CVPQA+V+WKFYDAQPCSDKAYKIEELFYS
Sbjct 6206 RKVQHMVVKSALLADKFTVLHDIGNPKAIRCVPQAEVDWKFYDAQPCSDKAYKIEELFYS 6265
Query 6295 YATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTP 6354
YATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTP
Sbjct 6266 YATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTP 6325
Query 6355 AFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHAN 6414
AFDKSAF +LKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHAN
Sbjct 6326 AFDKSAFTHLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHAN 6385
Query 6415 EYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEV 6474
EYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFT+LQSLENVA+NVVNKGHFDGQ GE
Sbjct 6386 EYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTKLQSLENVAYNVVNKGHFDGQSGEA 6445
Query 6475 PVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAAN 6534
PVSIINN VYTKVDG+DVE+FENKTTLPVNVAFELWAKRNIKPVPE+KILNNLGVDIAAN
Sbjct 6446 PVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAAN 6505
Query 6535 TVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVL 6594
VIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ L V FDGRV+GQVD FRNARNGVL
Sbjct 6506 NVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLIVLFDGRVEGQVDFFRNARNGVL 6565
Query 6595 ITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQE 6654
ITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQSR+L++
Sbjct 6566 ITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLED 6625
Query 6655 FKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESP 6714
FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR ++S
Sbjct 6626 FKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSL 6685
Query 6715 FELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTI 6774
+LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTI
Sbjct 6686 LKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTI 6745
Query 6775 DYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATL 6834
DY EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG++A +
Sbjct 6746 DYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVI 6805
Query 6835 PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLV 6894
PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLV
Sbjct 6806 PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLV 6865
Query 6895 DSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGF 6954
DSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTK+V K+NDSKEGFFTY+CGF
Sbjct 6866 DSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKHVLKDNDSKEGFFTYLCGF 6925
Query 6955 IQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPR 7014
I+QKLALGGSVA+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NYLGKP+
Sbjct 6926 IKQKLALGGSVAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGVNYLGKPK 6985
Query 7015 EQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLS 7074
EQIDGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI SLL
Sbjct 6986 EQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLE 7045
Query 7075 KGRLIIRENNRVVISSDVLVNN 7096
KGRLIIRENNRVV+SSD+LVNN
Sbjct 7046 KGRLIIRENNRVVVSSDILVNN 7067
>sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 PE=1 SV=1
Length=4405
Score = 9137 bits (23709), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 4401/4401 (100%), Positives = 4401/4401 (100%), Gaps = 0/4401 (0%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV
Sbjct 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK
Sbjct 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW
Sbjct 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI
Sbjct 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL
Sbjct 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC
Sbjct 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF
Sbjct 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA
Sbjct 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY
Sbjct 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV
Sbjct 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC
Sbjct 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG
Sbjct 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN 840
TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN
Sbjct 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN 840
Query 841 ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW 900
ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW
Sbjct 841 ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW 900
Query 901 SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL 960
SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL
Sbjct 901 SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL 960
Query 961 EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV 1020
EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV
Sbjct 961 EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV 1020
Query 1021 QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN
Sbjct 1021 QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
Query 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ 1140
NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ
Sbjct 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ 1140
Query 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE 1200
HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE
Sbjct 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE 1200
Query 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN 1260
QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN
Sbjct 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN 1260
Query 1261 GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV 1320
GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV
Sbjct 1261 GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV 1320
Query 1321 PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA 1380
PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA
Sbjct 1321 PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA 1380
Query 1381 HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND 1440
HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND
Sbjct 1381 HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND 1440
Query 1441 LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH 1500
LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH
Sbjct 1441 LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH 1500
Query 1501 FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL 1560
FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL
Sbjct 1501 FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL 1560
Query 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV
Sbjct 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
Query 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL
Sbjct 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
Query 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN
Sbjct 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
Query 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ
Sbjct 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
Query 1801 ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK 1860
ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK
Sbjct 1801 ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK 1860
Query 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY 1920
GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY
Sbjct 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY 1920
Query 1921 PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK
Sbjct 1921 PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
Query 1981 KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA 2040
KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA
Sbjct 1981 KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA 2040
Query 2041 CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV
Sbjct 2041 CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
Query 2101 DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC 2160
DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC
Sbjct 2101 DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC 2160
Query 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS
Sbjct 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
Query 2221 PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT 2280
PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT
Sbjct 2221 PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT 2280
Query 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV
Sbjct 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
Query 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV
Sbjct 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA
Sbjct 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH
Sbjct 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV
Sbjct 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG
Sbjct 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
Query 2641 FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN 2700
FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN
Sbjct 2641 FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN 2700
Query 2701 AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL 2760
AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL
Sbjct 2701 AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL 2760
Query 2761 KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI 2820
KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI
Sbjct 2761 KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI 2820
Query 2821 ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD 2880
ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD
Sbjct 2821 ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD 2880
Query 2881 FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE 2940
FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE
Sbjct 2881 FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE 2940
Query 2941 GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST 3000
GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST
Sbjct 2941 GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST 3000
Query 3001 SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL
Sbjct 3001 SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
Query 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV
Sbjct 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
Query 3121 SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL 3180
SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL
Sbjct 3121 SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL 3180
Query 3181 CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND 3240
CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND
Sbjct 3181 CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND 3240
Query 3241 FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY 3300
FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY
Sbjct 3241 FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY 3300
Query 3301 CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK 3360
CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK
Sbjct 3301 CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK 3360
Query 3361 TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV 3420
TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV
Sbjct 3361 TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV 3420
Query 3421 SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR 3480
SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR
Sbjct 3421 SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR 3480
Query 3481 WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN
Sbjct 3481 WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
Query 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW
Sbjct 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
Query 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV
Sbjct 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
Query 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK
Sbjct 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
Query 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM
Sbjct 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
Query 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL
Sbjct 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
Query 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL
Sbjct 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
Query 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA
Sbjct 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
Query 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED
Sbjct 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
Query 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY
Sbjct 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
Query 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ 4140
KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ
Sbjct 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ 4140
Query 4141 NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD 4200
NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD
Sbjct 4141 NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD 4200
Query 4201 GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV 4260
GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV
Sbjct 4201 GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV 4260
Query 4261 PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES 4320
PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES
Sbjct 4261 PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES 4320
Query 4321 FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG 4380
FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG
Sbjct 4321 FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG 4380
Query 4381 CSCDQLREPMLQSADAQSFLN 4401
CSCDQLREPMLQSADAQSFLN
Sbjct 4381 CSCDQLREPMLQSADAQSFLN 4401
>sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respiratory
syndrome coronavirus OX=694009 GN=1a PE=1 SV=1
Length=4382
Score = 7474 bits (19391), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3540/4408 (80%), Positives = 3938/4408 (89%), Gaps = 37/4408 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA + HGH +VELVAE++GIQYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGK+ CTLSEQLD+I++KRGVYCCR+HEHEIAW
Sbjct 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVASP ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + E+GPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+Q+S+L+PL F S+A
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIF+RTL+ A +S+ LQ+AA+TILDGIS+ SLRL+DAM++TSDL TN++++MAY
Sbjct 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ TSQWL+N+ GT EKL+P+ +W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVC+NGLMLLEIKD E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV EVQGYK+V
Sbjct 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ-YEYGTEDDYQGK 958
WS+AT+YLFD++GE +S MYCSFYPPDE+EE+ EEE T +EYGTEDDYQG
Sbjct 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
Query 959 PLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
PLEFGA++ ++ EEE+EEDWLDD ++Q+ E+
Sbjct 961 PLEFGASAETVRVEEEEEEDWLDDTTEQS-------------------EI-----EPEPE 996
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
VN F+GYLKLTDNV IK DIV+EA+ P V+VNAAN++LKHGGGVAGALNKA
Sbjct 997 PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKA 1056
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
TN AMQ ESDDYI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYENF
Sbjct 1057 TNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENF 1116
Query 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
N ++LLAPLLSAGIFGA P+ SL+VCV TVRT VY+AV DK LY+++V +L+ +
Sbjct 1117 NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPR- 1175
Query 1199 VEQKIAEIPKEEVKPFITESK---PSVEQRKQDDK-KIKACVEEVTTTLEETKFLTENLL 1254
E PK+E P +SK SV Q+ D K KIKAC++EVTTTLEETKFLT LL
Sbjct 1176 -----VEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLL 1230
Query 1255 LYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLA 1314
L+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML+
Sbjct 1231 LFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLS 1290
Query 1315 KALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWN 1374
+AL+KVP D YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSWN
Sbjct 1291 RALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWN 1350
Query 1375 LREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASL 1434
LREMLAHAEETRKLMP+C++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS+
Sbjct 1351 LREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASI 1410
Query 1435 INTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS 1494
I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSSS
Sbjct 1411 ITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSS 1470
Query 1495 KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVITF 1553
KT EEHF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGEV++
Sbjct 1471 KTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSL 1530
Query 1554 DNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSH 1613
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH +H
Sbjct 1531 DKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNH 1590
Query 1614 EGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNN 1673
EGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNN
Sbjct 1591 EGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN 1650
Query 1674 CYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMS 1733
CYL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM+
Sbjct 1651 CYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMT 1710
Query 1734 YLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQA 1793
+L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+ A
Sbjct 1711 HLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDA 1770
Query 1794 TKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALL 1853
T+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA L
Sbjct 1771 TQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHL 1830
Query 1854 TKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPID 1913
TK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPID
Sbjct 1831 TKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPID 1890
Query 1914 LVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYK 1973
LVP QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY+
Sbjct 1891 LVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYR 1950
Query 1974 HYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDA 2033
HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1951 HYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDT 2010
Query 2034 QGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHT 2093
QGMDNLACE +P SEEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+GH
Sbjct 2011 QGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHE 2070
Query 2094 DLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTT 2153
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + TT
Sbjct 2071 DLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITT 2130
Query 2154 TNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEA 2213
+N R RV NYMPY FTLL QLCTFT+STNSRI+AS+PTTIAKN+VKSV K CL+A
Sbjct 2131 SNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
Query 2214 SFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNS 2273
NY+KSP FSKL I +W LLLS+CLGSLI TAA GVL+SN G PSYC G RE YLNS
Sbjct 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNS 2250
Query 2274 TNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYIL 2333
+NVT +C GS PCS+CLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+L
Sbjct 2251 SNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYML 2310
Query 2334 FTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYV 2393
FT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY+
Sbjct 2311 FTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYI 2370
Query 2394 WKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCV 2453
WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC+
Sbjct 2371 WKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCL 2430
Query 2454 NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTY 2513
NCDTFC GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV VKNG++HLYFDKAGQKTY
Sbjct 2431 NCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTY 2490
Query 2514 ERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLD 2573
ERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES++KSASVYYSQLMCQPILLLD
Sbjct 2491 ERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLD 2550
Query 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
QALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF
Sbjct 2551 QALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTF 2610
Query 2634 ISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACID 2693
+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACID
Sbjct 2611 VSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACID 2670
Query 2694 CSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNV 2753
C+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV
Sbjct 2671 CNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNV 2730
Query 2754 VTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAID 2813
+TTKI+LKGGKIV+ K ++K TL+ + A + Y++ PVH +S H +++EIIGYKAI
Sbjct 2731 ITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQ 2790
Query 2814 GGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTI 2873
GVTRDI STD CFANKHA FD WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT+
Sbjct 2791 DGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTV 2850
Query 2874 LRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC 2933
LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYC
Sbjct 2851 LRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYC 2910
Query 2934 YDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
YDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2911 YDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE 2970
Query 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
G+C+STSGRWVLNN++YR+L GVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+
Sbjct 2971 VGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGII 3030
Query 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
AI+VTC AYYFM+FRR FGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYSV YLYLT
Sbjct 3031 AILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLT 3090
Query 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFS 3173
FY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNGV+FS
Sbjct 3091 FYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFS 3150
Query 3174 TFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCH 3233
TFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCH
Sbjct 3151 TFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCH 3210
Query 3234 LAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
LAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL
Sbjct 3211 LAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3270
Query 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
WLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LK
Sbjct 3271 WLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLK 3330
Query 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
VDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGF
Sbjct 3331 VDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGF 3390
Query 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
NIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYA
Sbjct 3391 NIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYA 3450
Query 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKE
Sbjct 3451 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
Query 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
LLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+
Sbjct 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLI 3570
Query 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMV
Sbjct 3571 LVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMV 3630
Query 3654 YMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMN 3713
YMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMN
Sbjct 3631 YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMN 3690
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITG
Sbjct 3691 VITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
NTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+
Sbjct 3751 NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKS 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ
Sbjct 3811 SIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPS 3953
LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPS
Sbjct 3871 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPS 3930
Query 3954 YAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 4013
YAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY
Sbjct 3931 YAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 3990
Query 4014 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4073
KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV
Sbjct 3991 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4050
Query 4074 IPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 4133
+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRA
Sbjct 4051 VPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRA 4110
Query 4134 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKW 4193
NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLKW
Sbjct 4111 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKW 4170
Query 4194 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4253
ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ
Sbjct 4171 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4230
Query 4254 AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
AGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE
Sbjct 4231 AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4290
Query 4314 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVC 4373
ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVC
Sbjct 4291 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 4350
Query 4374 GMWKGYGCSCDQLREPMLQSADAQSFLN 4401
GMWKGYGCSCDQLREP++QSADA +FLN
Sbjct 4351 GMWKGYGCSCDQLREPLMQSADASTFLN 4378
>sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus
HKU3 OX=442736 GN=1a PE=3 SV=1
Length=4376
Score = 7447 bits (19321), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3532/4407 (80%), Positives = 3926/4407 (89%), Gaps = 41/4407 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA + HGH +VELVAEL+GIQ+GRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAELDGIQFGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHS+G DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
TRYVDNNFCGPDGYPLECIKD LARAGK+ CTLSEQLD+I++KRGVYCCREHEHEI W
Sbjct 181 VVTRYVDNNFCGPDGYPLECIKDFLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERSEKSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSEKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + EVGPEHS+A+YHN S ++T LRKGGRT FGGCVFSYVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFSYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIG NHTG+ GE E LN++LLEIL +E+VNINIVGDF+ NEE+AIILASF
Sbjct 421 AYWVPRASANIGANHTGITGENVETLNEDLLEILNRERVNINIVGDFRFNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SAS SAF+ETVKGLDYK+FK IVESCGN+KVT GK GAWNIG+Q+SIL+PL F S+A
Sbjct 481 SASPSAFIETVKGLDYKSFKVIVESCGNYKVTNGKPVTGAWNIGQQRSILTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIFSRTL+ A +S+ LQ+AA+T LDGIS+ SLRL+DAM++TSDL TN++VVMAY
Sbjct 541 AGVIRSIFSRTLDAANHSILDLQRAAVTTLDGISEQSLRLVDAMVYTSDLLTNSVVVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ T QWL+N+ GT +KLKPV W+E K GVEFLRD WEI+KF+ T +++
Sbjct 601 VTGGLVQQTMQWLSNMLGTAVDKLKPVFTWVEAKLSAGVEFLRDAWEILKFLITGVFDVI 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI IKE V+ F +VNK L +C D + I G KL+ALNLGE F+ S+GLYR+C
Sbjct 661 KGQIQVATDNIKECVKIFLGVVNKALEMCLDQVTIAGTKLRALNLGEVFIAQSRGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG+ T + +EEVVLK+G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDAHDTVLTSEEVVLKSGELEALETPIDSFTSGAVVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVCINGLMLLE+++ E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCINGLMLLELENKEQYCALSPGLLATNNVFRLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELD R+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLTP+GIDLDE
Sbjct 841 KITFELDVRVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTPMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKP 959
WS+AT+YLFD++GE KL+S MYCSFYPPDE+E+ E E+ E + ++EYGTEDDY+G P
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCE--ECEDEEETCEHEYGTEDDYKGLP 958
Query 960 LEFGATSAALQ-PEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
LEFGA++ EEE+EEDWLDD + +
Sbjct 959 LEFGASTETPHVEEEEEEEDWLDDAIEAEPEPE--------------------------- 991
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
+ VN F GYLKLTDNV IK DIV+EA+ KPTV+VNAAN +LKHGGGVAGALNKA
Sbjct 992 PLPEEPVNQFVGYLKLTDNVAIKCIDIVKEAQSAKPTVIVNAANTHLKHGGGVAGALNKA 1051
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
TN AMQ ESD+YI NGPL VGGSC+LSGHNLA+ CLHVVGPN+N GED+QLLK AYENF
Sbjct 1052 TNGAMQNESDEYIRQNGPLTVGGSCLLSGHNLAEKCLHVVGPNLNAGEDVQLLKRAYENF 1111
Query 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
N +VLLAPLLSAGIFGA P+ SL++CV+ VRT VYLAV DK+LYD++V +L+ K
Sbjct 1112 NSQDVLLAPLLSAGIFGAKPLQSLKMCVEIVRTQVYLAVNDKSLYDQIVLDYLDSLKPK- 1170
Query 1199 VEQKIAEIPKEEVKPFITES---KPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL 1255
E P +E +P + E +P E+ KIKAC++EVTTTLEETKFLT LLL
Sbjct 1171 -----VESPNKEEEPKLEEPKAVQPVAEKPVDVKPKIKACIDEVTTTLEETKFLTNKLLL 1225
Query 1256 YIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAK 1315
+ DING L+ DS ++ D++FL+KDAPYIVGDV+ G +T V+IP KK+GGTTEMLA+
Sbjct 1226 FADINGKLYQDSQNMLRGEDMSFLEKDAPYIVGDVITSGDITCVIIPAKKSGGTTEMLAR 1285
Query 1316 ALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNL 1375
AL++VP YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS NEK+E+LGTVSWNL
Sbjct 1286 ALKEVPVAEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSETPNEKEEVLGTVSWNL 1345
Query 1376 REMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLI 1435
REMLAHAEETRKLMP+C++ +AI++TIQRKYKGIK+QEG+VDYG RF+FYTSK VAS+I
Sbjct 1346 REMLAHAEETRKLMPICLDVRAIMATIQRKYKGIKVQEGIVDYGVRFFFYTSKEPVASII 1405
Query 1436 NTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSK 1495
LN LNE LVTMP+GYVTHGLNLEEAAR MRSLK PA VSVSSPDAVTAYNGYLTSSSK
Sbjct 1406 TKLNSLNEPLVTMPIGYVTHGLNLEEAARCMRSLKAPAVVSVSSPDAVTAYNGYLTSSSK 1465
Query 1496 TPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTS-NPTTFHLDGEVITFD 1554
TPEE+F+ET SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T+ +P FHLDGEV+ D
Sbjct 1466 TPEEYFVETTSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTTGSPIEFHLDGEVLPLD 1525
Query 1555 NLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHE 1614
LK+LLSLREV+TIKVFTTVDN NLHT +VDMSMTYGQQFGPTYLDGADVTKIKPH +HE
Sbjct 1526 KLKSLLSLREVKTIKVFTTVDNTNLHTHIVDMSMTYGQQFGPTYLDGADVTKIKPHVNHE 1585
Query 1615 GKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNC 1674
GKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNNC
Sbjct 1586 GKTFFVLPSDDTLRSEAFEYYHTIDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNC 1645
Query 1675 YLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSY 1734
YL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM++
Sbjct 1646 YLSSVLLALQQVEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTH 1705
Query 1735 LFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQAT 1794
L QHANL+S KRVLNVVCK CGQ+ TTLKGVEAVMYMGTLSY++ K GV IPC CG+ AT
Sbjct 1706 LLQHANLESAKRVLNVVCKHCGQKTTTLKGVEAVMYMGTLSYDELKTGVSIPCVCGRNAT 1765
Query 1795 KYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLT 1854
+YLVQQES FVMMSAPPA+Y+L+ G F CA+EYTGNYQCGHY HIT+KETLY +DGA LT
Sbjct 1766 QYLVQQESSFVMMSAPPAEYKLQQGAFLCANEYTGNYQCGHYTHITAKETLYRVDGAHLT 1825
Query 1855 KSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL 1914
K SEYKGP+TDVFYKE SYTT IKPV+YKLDGV TEI+PKLD YYKK N+Y+TEQPIDL
Sbjct 1826 KMSEYKGPVTDVFYKETSYTTAIKPVSYKLDGVTYTEIEPKLDGYYKKGNAYYTEQPIDL 1885
Query 1915 VPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKH 1974
VP QP PNASFDNFK C N KFADDLNQ+TG+KKPASREL VTFFPDLNGDVVAIDY+H
Sbjct 1886 VPTQPMPNASFDNFKLTCSNTKFADDLNQMTGFKKPASRELTVTFFPDLNGDVVAIDYRH 1945
Query 1975 YTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQ 2034
Y+ SFKKGAKL+HKPI+WH+N TNK TYKPN WC+RCLWSTKPV+TSNSF+VL ED Q
Sbjct 1946 YSTSFKKGAKLVHKPILWHINQTTNKTTYKPNIWCLRCLWSTKPVDTSNSFEVLVVEDTQ 2005
Query 2035 GMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTD 2094
GMDNLACE SEEVVENPT+QK+++EC+VKTTEVVG++ILKP+ +K+T+E+GH D
Sbjct 2006 GMDNLACESQTTTSEEVVENPTVQKEIIECDVKTTEVVGNVILKPSEEGVKVTQELGHED 2065
Query 2095 LMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT 2154
LMAAYV+ +S+TIKKPNELS LGLKTLATHG AA+NSVPW I Y KPFL + T+
Sbjct 2066 LMAAYVEETSITIKKPNELSLALGLKTLATHGAAAINSVPWSKILAYVKPFLGQTAVITS 2125
Query 2155 NIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEAS 2214
N + +C+ RV +NYMPY TLL QLCTFT+STNSRIKAS+PTTIAKN+VKSV K CL+
Sbjct 2126 NCIKKCVQRVFSNYMPYVITLLFQLCTFTKSTNSRIKASLPTTIAKNSVKSVAKLCLDVC 2185
Query 2215 FNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNST 2274
NY+KSP FSKL I++W LLLS+CLGSL Y TA LGV +S+LG+PSYC G RE Y+NS+
Sbjct 2186 INYVKSPKFSKLFTIVMWLLLLSICLGSLTYVTAVLGVCLSSLGVPSYCDGVRELYINSS 2245
Query 2275 NVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILF 2334
NVT +C G PCSVCLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+LF
Sbjct 2246 NVTTMDFCQGYFPCSVCLSGLDSLDSYPALETIQVTISSYKLDLTFLGLAAEWLLAYMLF 2305
Query 2335 TRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVW 2394
T+FFY+LGL+AIMQ FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYYVW
Sbjct 2306 TKFFYLLGLSAIMQAFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYVW 2365
Query 2395 KSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVN 2454
KSYVH++DGC SSTCMMCYKRNRATRVECTTIVNGV+RSFYVYANGG+GFCK HNWNC+N
Sbjct 2366 KSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGVKRSFYVYANGGRGFCKAHNWNCLN 2425
Query 2455 CDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYE 2514
CDTFCAGSTFISDEVARDLSLQFKRPINPTDQS+Y+VDSVTVKNG++HLYFDKAGQKTYE
Sbjct 2426 CDTFCAGSTFISDEVARDLSLQFKRPINPTDQSAYVVDSVTVKNGALHLYFDKAGQKTYE 2485
Query 2515 RHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQ 2574
RH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES+AKSASVYYSQLMCQPILLLDQ
Sbjct 2486 RHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESAAKSASVYYSQLMCQPILLLDQ 2545
Query 2575 ALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFI 2634
ALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF+
Sbjct 2546 ALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFV 2605
Query 2635 SAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDC 2694
SAARQG VD+DV+TKDV+ECLKLSH SDIEVTGDSCNN+MLTYNKVENMTPRDLGACIDC
Sbjct 2606 SAARQGVVDTDVDTKDVIECLKLSHHSDIEVTGDSCNNFMLTYNKVENMTPRDLGACIDC 2665
Query 2695 SARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVV 2754
+ARHINAQVAKSHN++L+WNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV+
Sbjct 2666 NARHINAQVAKSHNVSLVWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVI 2725
Query 2755 TTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDG 2814
TTKI+LKGGK+V+ W K L+KVTL+ + A Y+I PVH +S H +++EIIGYKAI
Sbjct 2726 TTKISLKGGKVVSTWFKLLLKVTLLCVLAALFCYVIMPVHSLSVHDGYTNEIIGYKAIQD 2785
Query 2815 GVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTIL 2874
GVTRDI STD CFANKHA FD+WFSQRGGSY NDK CP++AA+ITRE+GF+VPGLPGT+L
Sbjct 2786 GVTRDIVSTDDCFANKHAGFDSWFSQRGGSYRNDKNCPVVAAIITREIGFIVPGLPGTVL 2845
Query 2875 RTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCY 2934
R NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYCY
Sbjct 2846 RALNGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCY 2905
Query 2935 DTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEA 2994
DTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2906 DTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEV 2965
Query 2995 GVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVA 3054
GVC+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+A
Sbjct 2966 GVCLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIA 3025
Query 3055 IVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTF 3114
I+VTC AYYFM+FRRAFGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYS+ YLYLTF
Sbjct 3026 ILVTCAAYYFMKFRRAFGEYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFYLYLTF 3085
Query 3115 YLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFST 3174
Y TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KHF+WFFSNYLK+RV+FNGV+FST
Sbjct 3086 YFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHFHWFFSNYLKKRVMFNGVTFST 3145
Query 3175 FEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL 3234
FEEAALCTFLLNKEMYL+LRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCHL
Sbjct 3146 FEEAALCTFLLNKEMYLRLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHL 3205
Query 3235 AKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW 3294
AKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW
Sbjct 3206 AKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW 3265
Query 3295 LDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKV 3354
LDD VYCPRHV+CT+EDMLNPNY+DLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LKV
Sbjct 3266 LDDTVYCPRHVVCTAEDMLNPNYDDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKV 3325
Query 3355 DTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFN 3414
DT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGFN
Sbjct 3326 DTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFN 3385
Query 3415 IDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAA 3474
IDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAA
Sbjct 3386 IDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAA 3445
Query 3475 VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKEL 3534
VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKEL
Sbjct 3446 VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKEL 3505
Query 3535 LQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVL 3594
LQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+L
Sbjct 3506 LQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLIL 3565
Query 3595 VQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVY 3654
VQSTQWSLFFF+YENAFLPFA+GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMVY
Sbjct 3566 VQSTQWSLFFFVYENAFLPFALGIMAVAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVY 3625
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNV 3714
MPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMNV
Sbjct 3626 MPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNV 3685
Query 3715 LTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGN 3774
+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITGN
Sbjct 3686 ITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGN 3745
Query 3775 TLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNS 3834
TLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+S
Sbjct 3746 TLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSS 3805
Query 3835 IDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQL 3894
IDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQL
Sbjct 3806 IDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQL 3865
Query 3895 HNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSY 3954
HNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSY
Sbjct 3866 HNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSY 3925
Query 3955 AAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYK 4014
AA+ATAQEAYEQAV+NGDSEVVLKKLKKSLNVAKSEFD DAAMQRKLEKMADQAMTQMYK
Sbjct 3926 AAYATAQEAYEQAVSNGDSEVVLKKLKKSLNVAKSEFDHDAAMQRKLEKMADQAMTQMYK 3985
Query 4015 QARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVI 4074
QARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV+
Sbjct 3986 QARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVV 4045
Query 4075 PDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN 4134
PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRAN
Sbjct 4046 PDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN 4105
Query 4135 SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN KGGRFVLALLSD QDLKWA
Sbjct 4106 SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNAKGGRFVLALLSDHQDLKWA 4165
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA
Sbjct 4166 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4225
Query 4255 GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA 4314
GNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA
Sbjct 4226 GNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA 4285
Query 4315 NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCG 4374
NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVCG
Sbjct 4286 NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCG 4345
Query 4375 MWKGYGCSCDQLREPMLQSADAQSFLN 4401
MWKGYGCSCDQLREPM+QSADA +FLN
Sbjct 4346 MWKGYGCSCDQLREPMMQSADASTFLN 4372
>sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus
Rp3/2004 OX=349344 GN=1a PE=3 SV=1
Length=4380
Score = 7445 bits (19316), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3519/4409 (80%), Positives = 3932/4409 (89%), Gaps = 41/4409 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK GTCG+VE+EKGV
Sbjct 1 MESLVLGINEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKSGTCGIVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQ EQPYVFIKRSDA+ HGH + ELVAEL+G+QYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQPEQPYVFIKRSDAQGTDHGHRVRELVAELDGVQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHS+G DLKS+DLGDELGTDP ED+++NWNTKH SGV REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGVLRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A TRYVDNNFCGPDGYPLECIKDLLARAGK+ CTLSEQLD+I++KRGVYCCR+H HEIAW
Sbjct 181 ALTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCRDHGHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TCGYL
Sbjct 301 RSVYPVATPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVSEGPNTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + E+GPEHS A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSAADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF+LNEE+AIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFQLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+ +S+L+PL F S+A
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPIKGAWNIGQHRSVLTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIFSRTL+ A +S+ LQ+AA+TILD IS+ SLRL+DAM++TS+L TN++++MAY
Sbjct 541 AGVIRSIFSRTLDAANHSIPDLQRAAVTILDSISEQSLRLVDAMVYTSNLLTNSVIIMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ TSQWL+N+ T EKL+P+ W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 VTGGLVQQTSQWLSNLLDTTVEKLRPIFAWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNIKDCVKCFVDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAVVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVCINGLMLLEIK E+YCAL+P ++ TNN F LKGGAPTK VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCINGLMLLEIKANEQYCALSPGLLATNNVFRLKGGAPTKGVTFGEDTVVEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEP--STQYEYGTEDDYQG 957
WS+AT+YLFD+SGE KL+S MYCSFYPPDE+E+ + EEEE + ++EYGTE+DY+G
Sbjct 901 WSVATFYLFDDSGEEKLSSRMYCSFYPPDEEEDCEEYEEEEEVSERTCEHEYGTEEDYKG 960
Query 958 KPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELT 1017
PLEFGA++ +Q EE++EEDWLDD + +
Sbjct 961 LPLEFGASTDIIQVEEQEEEDWLDDAVEAEPEPE-------------------------- 994
Query 1018 PVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
+ VN +GYLKLTDNV IK DIVEEA+ P V+VNAAN++LKHGGGVAGALNK
Sbjct 995 -PLHEEPVNQLTGYLKLTDNVAIKCVDIVEEAQNANPMVIVNAANIHLKHGGGVAGALNK 1053
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
ATN AMQ ESD YI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYEN
Sbjct 1054 ATNGAMQKESDHYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYEN 1113
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK 1197
FN ++LLAPLLSAGIFGA P+ SL++CV TVRT VY+ V DK LY+++V +L+ K
Sbjct 1114 FNSQDILLAPLLSAGIFGAKPLQSLQMCVQTVRTQVYIVVNDKVLYEQVVMDYLDSLKPK 1173
Query 1198 QVEQKIAEIPKEEVKP---FITESKPSVEQRKQDDK-KIKACVEEVTTTLEETKFLTENL 1253
E PK+EV P + + SV Q+ D K KIKAC++EVTTTLEETKFLT L
Sbjct 1174 ------VEAPKQEVLPKAEYPKVDEKSVVQKTIDVKPKIKACIDEVTTTLEETKFLTNKL 1227
Query 1254 LLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEML 1313
LL+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML
Sbjct 1228 LLFTDINGKLYQDSKNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEML 1287
Query 1314 AKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSW 1373
++AL+KVP + YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSW
Sbjct 1288 SRALKKVPINEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSETPNAKEEILGTVSW 1347
Query 1374 NLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVAS 1433
NLREMLAHAEETRKLMPVC++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS
Sbjct 1348 NLREMLAHAEETRKLMPVCMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVAS 1407
Query 1434 LINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSS 1493
+I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSS
Sbjct 1408 IITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAIVSVSSPDAVTTYNGYLTSS 1467
Query 1494 SKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVIT 1552
SKT E+HF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRG+K VY+T +P FHLDGEV+
Sbjct 1468 SKTSEDHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGEKIVYHTLESPVKFHLDGEVLP 1527
Query 1553 FDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNS 1612
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQ GPTYL+GADVTKIKPH +
Sbjct 1528 LDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQLGPTYLEGADVTKIKPHVN 1587
Query 1613 HEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADN 1672
HEGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADN
Sbjct 1588 HEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADN 1647
Query 1673 NCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETM 1732
NCYL++ LL LQQIE+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM
Sbjct 1648 NCYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETM 1707
Query 1733 SYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQ 1792
++L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+
Sbjct 1708 THLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKMGVSIPCVCGRD 1767
Query 1793 ATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGAL 1852
AT+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA
Sbjct 1768 ATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAH 1827
Query 1853 LTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPI 1912
LTK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPI
Sbjct 1828 LTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPI 1887
Query 1913 DLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDY 1972
DL+P QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY
Sbjct 1888 DLIPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDY 1947
Query 1973 KHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSED 2032
+HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1948 RHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVED 2007
Query 2033 AQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGH 2092
QGMDNLACE +P EEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+ H
Sbjct 2008 TQGMDNLACESQQPTPEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELDH 2067
Query 2093 TDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVST 2152
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + T
Sbjct 2068 EDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWGKILAYVKPFLGQAAVT 2127
Query 2153 TTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLE 2212
T+N R + R+ NYMPY TLL QLCTFT+STNSRI+AS+PTTIAKN+V+ + + CL+
Sbjct 2128 TSNCAKRLVQRMFNNYMPYVLTLLFQLCTFTKSTNSRIRASLPTTIAKNSVRGIVRLCLD 2187
Query 2213 ASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLN 2272
A NY+KSP FSKL I +W LLLS+CLGSLIY TAALGVL+SN G PSYC+G RE YLN
Sbjct 2188 AGINYVKSPKFSKLFTIAMWLLLLSICLGSLIYVTAALGVLLSNFGAPSYCSGVRESYLN 2247
Query 2273 STNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYI 2332
S+NVT +C GS PCSVCLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEWF AY+
Sbjct 2248 SSNVTTMDFCEGSFPCSVCLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWFFAYM 2307
Query 2333 LFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYY 2392
LFT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY
Sbjct 2308 LFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYY 2367
Query 2393 VWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNC 2452
+WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC
Sbjct 2368 IWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNC 2427
Query 2453 VNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKT 2512
+NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSY+VDSV VKNG++HLYFDKAGQKT
Sbjct 2428 LNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAGQKT 2487
Query 2513 YERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLL 2572
YERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES+AKSASVYYSQLMCQPILLL
Sbjct 2488 YERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPILLL 2547
Query 2573 DQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLST 2632
DQALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLST
Sbjct 2548 DQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLST 2607
Query 2633 FISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACI 2692
F+SA+RQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACI
Sbjct 2608 FVSASRQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACI 2667
Query 2693 DCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVN 2752
DC+ARHINAQVA+SHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVN
Sbjct 2668 DCNARHINAQVARSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVN 2727
Query 2753 VVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAI 2812
V+TTKI+LKGGKIV+ W K ++K TL+ + A + Y++ PVH++S H +++EIIGYKAI
Sbjct 2728 VITTKISLKGGKIVSTWFKIMLKATLLCVLAALVCYIVMPVHILSVHGGYTNEIIGYKAI 2787
Query 2813 DGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGT 2872
GVTRDI STD CFANKHA FD+WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT
Sbjct 2788 QDGVTRDIVSTDDCFANKHAGFDSWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGT 2847
Query 2873 ILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPY 2932
+LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DF+TSACVLAAECTIFKDA GKPVPY
Sbjct 2848 VLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFSTSACVLAAECTIFKDAMGKPVPY 2907
Query 2933 CYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERS 2992
CYDTN+LEGS++Y LRPDTRYVLMDGSIIQFPN YLEGSVRVVTTFD+EYCRHGTCERS
Sbjct 2908 CYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNAYLEGSVRVVTTFDAEYCRHGTCERS 2967
Query 2993 EAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGI 3052
EAG+C+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI
Sbjct 2968 EAGICLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGI 3027
Query 3053 VAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYL 3112
+AI+VTC AYYFM+FRRAFGEY+HVVA N LFLMSFT+LCL P YSFLPGVYSV YLYL
Sbjct 3028 IAILVTCAAYYFMKFRRAFGEYNHVVAANAPLFLMSFTILCLAPAYSFLPGVYSVFYLYL 3087
Query 3113 TFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSF 3172
TFY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KHF+WFF+NYL++RVVFNGV+F
Sbjct 3088 TFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHFHWFFNNYLRKRVVFNGVTF 3147
Query 3173 STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACC 3232
STFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACC
Sbjct 3148 STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACC 3207
Query 3233 HLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG 3292
HLAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG
Sbjct 3208 HLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG 3267
Query 3293 LWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKL 3352
LWLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+L
Sbjct 3268 LWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRL 3327
Query 3353 KVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVG 3412
KVDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVG
Sbjct 3328 KVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVG 3387
Query 3413 FNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLY 3472
FNIDYDCVSFCYMHHMELPT VHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLY
Sbjct 3388 FNIDYDCVSFCYMHHMELPTEVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLY 3447
Query 3473 AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLK 3532
AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LK
Sbjct 3448 AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALK 3507
Query 3533 ELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLL 3592
ELLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ KR +KGTHHW+LLT LTSLL
Sbjct 3508 ELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKRIVKGTHHWMLLTFLTSLL 3567
Query 3593 VLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNM 3652
+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNM
Sbjct 3568 ILVQSTQWSLFFFVYENAFLPFTLGIMAVAACAMLLVKHKHAFLCLFLLPSLATVAYFNM 3627
Query 3653 VYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLM 3712
VYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL+LMTARTVYDD ARRVWTLM
Sbjct 3628 VYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVWTLM 3687
Query 3713 NVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFIT 3772
NV+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FIT
Sbjct 3688 NVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFIT 3747
Query 3773 GNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK 3832
GNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK
Sbjct 3748 GNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK 3807
Query 3833 NSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV 3892
+SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV
Sbjct 3808 SSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV 3867
Query 3893 QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP 3952
QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP
Sbjct 3868 QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP 3927
Query 3953 SYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQM 4012
SYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR+AAMQRKLEKMADQAMTQM
Sbjct 3928 SYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRNAAMQRKLEKMADQAMTQM 3987
Query 4013 YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV 4072
YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV
Sbjct 3988 YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV 4047
Query 4073 VIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALR 4132
V+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+M+NS NLAWPLIVTALR
Sbjct 4048 VVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMENSSNLAWPLIVTALR 4107
Query 4133 ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLK 4192
ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLK
Sbjct 4108 ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLK 4167
Query 4193 WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRL 4252
WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL+FIKGLNNLNRGMVLGSLAATVRL
Sbjct 4168 WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLHFIKGLNNLNRGMVLGSLAATVRL 4227
Query 4253 QAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP 4312
QAGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP
Sbjct 4228 QAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP 4287
Query 4313 EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTV 4372
EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTV
Sbjct 4288 EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTV 4347
Query 4373 CGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
CGMWKGYGCSCDQLREPM+QSADA +FLN
Sbjct 4348 CGMWKGYGCSCDQLREPMMQSADASTFLN 4376
>sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus
279/2005 OX=389167 GN=1a PE=3 SV=1
Length=4388
Score = 7442 bits (19309), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3523/4412 (80%), Positives = 3924/4412 (89%), Gaps = 39/4412 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESL G +EKTHVQLSLPVLQVRDVLVRGFGDSVEE L+EAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLALGVSEKTHVQLSLPVLQVRDVLVRGFGDSVEEALAEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA+ HG+ +VELVAEL+GIQYGRSG TLGVLVPHVGE PVAYR
Sbjct 61 LPQLEQPYVFIKRSDAQGTNHGYKVVELVAELDGIQYGRSGTTLGVLVPHVGETPVAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLG ELGTDP ED+++NWNTKH GV REL+RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGVELGTDPIEDYEQNWNTKHGGGVLRELIRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A+TRYVDNNFCGPDGYPLECIKDLLARAGK+ CTLSEQLD+I++KRGVYCCREHEHEI W
Sbjct 181 AFTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERSEKSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSEKSYERQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + EVGPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PANAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIG +HTG+ G+ E LN++L+EIL +++VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASANIGASHTGITGDNVETLNEDLMEILNRDRVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SAST AFV+TVKGLDYK FK IVESCGNFKVT+G+AKKGAWNIG++KSIL+PLY F S+A
Sbjct 481 SASTCAFVDTVKGLDYKTFKDIVESCGNFKVTRGRAKKGAWNIGQEKSILTPLYGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIF+R L+TA +S+ LQ+AAITILDGIS+ SLRLIDAM++TSDL TN+++VMAY
Sbjct 541 AGVIRSIFTRALDTANHSIPDLQRAAITILDGISEQSLRLIDAMVYTSDLLTNSVIVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ +QWL+N+ GT +KLKPV W+E K G+EFLRD WEI+KF+ T +IV
Sbjct 601 VTGGLVQQITQWLSNMLGTTVDKLKPVFTWVEAKLSAGIEFLRDAWEILKFLVTGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + +KE V+ F ++NK L +C D +II GAKL+ LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNLKECVKAFLDVLNKALEMCIDQVIIAGAKLRTLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPL+APKE+ F EG++ T +EEVVLK G+L+ LE P ++G
Sbjct 721 IRGKEQLQLLMPLRAPKEVTFFEGDSHDTVFTSEEVVLKNGELEALETPVDSFTNGAVIG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVC+NGLMLLE+KD E+YCAL+P ++ TNN F+LKGGAP K VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCVNGLMLLELKDKEQYCALSPGLLATNNVFSLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 KITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ--YEYGTEDDYQG 957
WS+AT+YLFD++GE KL+S MYCSFYPPDE+E+ + E+EE P +EYGTEDDY+G
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCEEYEDEEEIPEETCEHEYGTEDDYKG 960
Query 958 KPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELT 1017
PLEFGA++ + QQ +++ + + E
Sbjct 961 LPLEFGAST----------------EIQQVDEEEEEDWLEEAIAAKPEPEPL-------- 996
Query 1018 PVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
VN F+GYLKLTDNV IK DIV+EA+ KPTV+VNAANV+LKHGGGVAGALNK
Sbjct 997 ---PEEPVNQFTGYLKLTDNVAIKCVDIVKEAQHAKPTVIVNAANVHLKHGGGVAGALNK 1053
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
ATN AMQ ESDDYI NGPL VGGSC+LSGHNLAK C+HVVGPN+N GED+QLLK+AY N
Sbjct 1054 ATNGAMQQESDDYIKKNGPLTVGGSCLLSGHNLAKKCMHVVGPNLNAGEDVQLLKAAYAN 1113
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK 1197
FN +VLLAPLLSAGIFGA P+ SL++CV+TVRT VY AV D++LYD +V +L+ K
Sbjct 1114 FNSQDVLLAPLLSAGIFGAKPLQSLKMCVETVRTQVYFAVNDQDLYDHVVLGYLDSLKPK 1173
Query 1198 QVE---QKIAEIPKEEVKPFITESKPSVEQ----RKQDDKKIKACVEEVTTTLEETKFLT 1250
VE Q+ E+ ++ +T+ +E+ K D K KA +EEV T+LEETKFLT
Sbjct 1174 -VETPTQENLELKEQPAVETLTQENLELEELPVIEKPVDVKFKARIEEVNTSLEETKFLT 1232
Query 1251 ENLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTT 1310
LLL+ DING L+ DS ++ D+ FL+KDAPYIVGDV+ G +T V+IP KKAGGTT
Sbjct 1233 SRLLLFADINGKLYQDSQNMLRGEDMFFLEKDAPYIVGDVISSGDITCVIIPAKKAGGTT 1292
Query 1311 EMLAKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGT 1370
EMLAKAL+KVP YITTYPGQG GYT+EEAKT L+KCKS FY+LPS N+K+EILGT
Sbjct 1293 EMLAKALKKVPVSEYITTYPGQGCAGYTLEEAKTALRKCKSVFYVLPSKTPNDKEEILGT 1352
Query 1371 VSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTT 1430
VSWNLREMLAHAEETRKLM +C++ KA++STI R+YKGIK+QEG+VDYG RF+FYTSK
Sbjct 1353 VSWNLREMLAHAEETRKLMLICMDVKALMSTIHRRYKGIKVQEGIVDYGVRFFFYTSKEP 1412
Query 1431 VASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYL 1490
VAS+I LN LNE LVTMP+GYVTHGLNLEEAAR MRSLK PA VSVSSPDAVT YNGYL
Sbjct 1413 VASIITKLNLLNEPLVTMPIGYVTHGLNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYL 1472
Query 1491 TSSSKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGE 1549
TSSSKT EEHFIET+SLAG Y+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGE
Sbjct 1473 TSSSKTSEEHFIETVSLAGMYRDWSYSGQRTELGVEFLKRGDKVVYHTVGSPIQFHLDGE 1532
Query 1550 VITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKP 1609
V+ D LK+LLSLREVRTIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKP
Sbjct 1533 VLLLDKLKSLLSLREVRTIKVFTTVDNTNLHTQIVDMSMTYGQQFGPTYLDGADVTKIKP 1592
Query 1610 HNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKW 1669
H HEGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQ+ GLTSIKW
Sbjct 1593 HAKHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQIGGLTSIKW 1652
Query 1670 ADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVR 1729
ADNNCYL++ LL LQQIE+KFN PALQ+AYYRARAG+AANFCALILAY N+TVGELGDVR
Sbjct 1653 ADNNCYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAYSNRTVGELGDVR 1712
Query 1730 ETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTC 1789
ETM++L QHANL+S KRVLNVVCKTCGQ+ TTL GVEAVMYMGTLSYE+ K GV IPC C
Sbjct 1713 ETMTHLLQHANLESAKRVLNVVCKTCGQKSTTLTGVEAVMYMGTLSYEELKTGVTIPCIC 1772
Query 1790 GKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCID 1849
G+ AT+YLVQQES FVMMSAPP++Y L+ G F CA+EYTG+YQCGHY H+T KETLY ID
Sbjct 1773 GRDATQYLVQQESSFVMMSAPPSEYTLQQGAFLCANEYTGSYQCGHYTHVTVKETLYRID 1832
Query 1850 GALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTE 1909
GA LTK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV+ TEI PKLD YYKKDN+Y+TE
Sbjct 1833 GAYLTKMSEYKGPVTDVFYKEISYTTTIKPVSYKLDGVIYTEIQPKLDEYYKKDNAYYTE 1892
Query 1910 QPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVA 1969
QPIDLVP QP PNASFDNFK C N KFADDLNQ+TG+KKPASREL VTFFPDLNGDVVA
Sbjct 1893 QPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFKKPASRELSVTFFPDLNGDVVA 1952
Query 1970 IDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLK 2029
IDY+HY+ SFKKGAKLLHKPI+WH+N TNK TYKPNTWC+RCLWSTKPVETSNSF+VL+
Sbjct 1953 IDYRHYSASFKKGAKLLHKPIIWHINQTTNKTTYKPNTWCLRCLWSTKPVETSNSFEVLE 2012
Query 2030 SEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEE 2089
ED QGMDNLACE P SEEVVENPTIQK+V+EC+VKT EVVG++ILKP+ +K+T+E
Sbjct 2013 VEDTQGMDNLACESQTPTSEEVVENPTIQKEVIECDVKTIEVVGNVILKPSEEGVKVTQE 2072
Query 2090 VGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKV 2149
+GH DLMAAYV+ +S+TIKKPNELS LGL+TLATHG AA+NSVPW I Y KPFL +
Sbjct 2073 LGHEDLMAAYVEETSITIKKPNELSLALGLRTLATHGAAAINSVPWSKILAYVKPFLGQA 2132
Query 2150 VSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKF 2209
TTTN + RC+ RV NYMPY TLL QLCTFTRSTNSRI+AS+PTTIAKN+VKSV K
Sbjct 2133 AVTTTNCIKRCVQRVFNNYMPYVITLLFQLCTFTRSTNSRIRASLPTTIAKNSVKSVAKL 2192
Query 2210 CLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREG 2269
CL+ NY+KSP FSKL I +W LLLS+CLGSLIY TAA GVL+SNLG+PSYC G RE
Sbjct 2193 CLDVCINYVKSPKFSKLFTIAMWLLLLSICLGSLIYVTAAFGVLLSNLGIPSYCDGVRES 2252
Query 2270 YLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFL 2329
Y+NS+NVT +C GS CSVCL+GLDSLD+YP+LETIQ+TISS+K DLT+ GL AEWFL
Sbjct 2253 YVNSSNVTTMDFCEGSFLCSVCLNGLDSLDSYPALETIQVTISSYKLDLTSLGLAAEWFL 2312
Query 2330 AYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFAS 2389
AY+LFT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFA
Sbjct 2313 AYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFAF 2372
Query 2390 FYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHN 2449
YYVWKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HN
Sbjct 2373 CYYVWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKAHN 2432
Query 2450 WNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAG 2509
WNC+NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSY+VDSV VKNG++HLYFDKAG
Sbjct 2433 WNCLNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAG 2492
Query 2510 QKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPI 2569
QKTYERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES+AKSASVYYSQLMCQPI
Sbjct 2493 QKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPI 2552
Query 2570 LLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNV 2629
LLLDQALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD V
Sbjct 2553 LLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGV 2612
Query 2630 LSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLG 2689
LSTF+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLG
Sbjct 2613 LSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLG 2672
Query 2690 ACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQ 2749
ACIDC+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQ
Sbjct 2673 ACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQ 2732
Query 2750 VVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGY 2809
VVN +TTKI+LKGGKIV+ W K ++K TL+ + A Y+I PVH +S H +++EIIGY
Sbjct 2733 VVNAITTKISLKGGKIVSTWFKLMLKATLLCVLAALFCYIIMPVHSLSVHDGYTNEIIGY 2792
Query 2810 KAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGL 2869
KAI GVTRDI +TD CFANKHA FD+WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGL
Sbjct 2793 KAIQDGVTRDIMATDDCFANKHAGFDSWFSQRGGSYRNDKSCPVVAAIITREIGFIVPGL 2852
Query 2870 PGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKP 2929
PGT+LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKP
Sbjct 2853 PGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKP 2912
Query 2930 VPYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTC 2989
VPYCYDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTC
Sbjct 2913 VPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTC 2972
Query 2990 ERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVA 3049
ERSEAGVC+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VA
Sbjct 2973 ERSEAGVCLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVA 3032
Query 3050 GGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIY 3109
GGI+AI+VTC AYYFM+FRRAFGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYS+ Y
Sbjct 3033 GGIIAILVTCAAYYFMKFRRAFGEYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFY 3092
Query 3110 LYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNG 3169
LYLTFY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNG
Sbjct 3093 LYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNG 3152
Query 3170 VSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREA 3229
V+FSTFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREA
Sbjct 3153 VTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREA 3212
Query 3230 ACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT 3289
ACCHLAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT
Sbjct 3213 ACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT 3272
Query 3290 LNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCV 3349
LNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+
Sbjct 3273 LNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCL 3332
Query 3350 LKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCG 3409
L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN+TIKGSFLNGSCG
Sbjct 3333 LRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNYTIKGSFLNGSCG 3392
Query 3410 SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLA 3469
SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLA
Sbjct 3393 SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLA 3452
Query 3470 WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA 3529
WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA
Sbjct 3453 WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA 3512
Query 3530 SLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILT 3589
+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LT
Sbjct 3513 ALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLT 3572
Query 3590 SLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAY 3649
SLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAY
Sbjct 3573 SLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAY 3632
Query 3650 FNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVW 3709
FNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL+LMTARTVYDD ARRVW
Sbjct 3633 FNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVW 3692
Query 3710 TLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIF 3769
TLMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+
Sbjct 3693 TLMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLL 3752
Query 3770 FITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL 3829
FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL
Sbjct 3753 FITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL 3812
Query 3830 PPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA 3889
PPK+SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA
Sbjct 3813 PPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA 3872
Query 3890 QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFS 3949
QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFS
Sbjct 3873 QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFS 3932
Query 3950 SLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM 4009
SLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM
Sbjct 3933 SLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM 3992
Query 4010 TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK 4069
TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK
Sbjct 3993 TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK 4052
Query 4070 LMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVT 4129
LMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNS NLAWPLIVT
Sbjct 4053 LMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSQNLAWPLIVT 4112
Query 4130 ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQ 4189
ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD Q
Sbjct 4113 ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQ 4172
Query 4190 DLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAAT 4249
DLKWARFPKSDGTGTIYTELEPPCRFVTDTP+GPKVKYLYFIKGLNNLNRGMVLGSLAAT
Sbjct 4173 DLKWARFPKSDGTGTIYTELEPPCRFVTDTPRGPKVKYLYFIKGLNNLNRGMVLGSLAAT 4232
Query 4250 VRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT 4309
VRLQAGNATEVPANS VLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT
Sbjct 4233 VRLQAGNATEVPANSAVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT 4292
Query 4310 VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIP TCANDPVGFTLKNTV
Sbjct 4293 VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPATCANDPVGFTLKNTV 4352
Query 4370 CTVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
CTVCG WKGYGCSCDQLREPM+QSADA +FLN
Sbjct 4353 CTVCGTWKGYGCSCDQLREPMMQSADASTFLN 4384
>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930
Score = 6357 bits (16492), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3387/7182 (47%), Positives = 4510/7182 (63%), Gaps = 421/7182 (6%)
Query 28 VRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV--LPQLEQPYVFIKRSDARTAPHG-HV 84
V G+ +EE L A+Q L+ LV V + P + V I S G
Sbjct 29 VTGWDIPIEEALEYAKQQLRTPEPQLVFVPYYLSHAPGISGDRVVITDSIWYATNFGWQP 88
Query 85 MVELVAELEGIQYGRSGETLGVLVPH------VGEIPVAYRKVLLRKNGNKGAGGHSYGA 138
+ EL + +G++YGR G T GVL+P +G+I + RK G G +S
Sbjct 89 IRELAMDKDGVRYGRGG-THGVLLPMQDPSFIMGDIDIQIRKY--------GIGANSPPD 139
Query 139 DLKSFDLGDELGTD--PYEDFQENW-NTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
L +D + G D PY DF +N TK + ++ G DNN G
Sbjct 140 VLPLWDGFSDPGPDVGPYLDFPDNCCPTKPKAKRGGDVYLSDQYG-----FDNN-----G 189
Query 196 YPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPF 255
+E + LL K+ TL + L + G Y R+E Y+L +
Sbjct 190 ILVEPVMKLLGVI-KSDFTLEQLLAAL----GKY--------------RTEDGYDLPDGY 230
Query 256 ---EIKLAKK------------FDTFNGECPNFVFPLN--SIIKTIQPRVEKKKLDGFMG 298
IK+ +K P + +P + S+++ +P
Sbjct 231 VKVAIKVGRKAVPVLKQSIFTVVGVTEQLVPGYYYPFSTSSVVEHTKPTRGGPVGKTVEA 290
Query 299 RIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTE-NLTKEGATTC 357
+ S+Y N N +KC +C W + CG E LT ++C
Sbjct 291 VMLSLY---GTNNYNPATPVARLKCSYCDYYGWTPLKDIGTVNCLCGAEFQLT----SSC 343
Query 358 GYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRT-IAFGGCVFSYVGC 416
V+K P C + G++ I G RT ++FGG ++S +G
Sbjct 344 VDAESAGVIK---PGC----------VMLLDKSPGMRLI--PGNRTYVSFGGAIWSPIGK 388
Query 417 HNKCAYWVPRASANIGCNHTGVVGEG-SEGLNDNLLEILQKEKVNINIVGDFKLNEEIAI 475
N WVPRA + + H+G VG G + +N L+E L + I + D N A
Sbjct 389 VNGVTVWVPRAYSIVAGEHSGAVGSGDTVAINKELVEYLIE---GIRVDADTLDNPTCAT 445
Query 476 ILASFSASTSA----FVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILS 531
+A+ T A VE+++GL C K+ G E +
Sbjct 446 FIANLDCDTKAPVVHTVESLQGL-----------CLANKIMLGDKP---LPTDEFHPFIV 491
Query 532 PLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLA 591
L A+ + A ++ SRT E ++ VR ++ +Q+ ++ +
Sbjct 492 GL-AYHVQRACWYGALASRTFEAFRDFVRTEEER-------FAQFFGKVCAPI------- 536
Query 592 TNNLVVMAYITGGVVQLTSQWLTN------------IFGTVYEKLKPVLDWLEEKFKEGV 639
N V +AY TG V ++ + N + V + LKP+L+W+ +K +
Sbjct 537 -NGCVYLAYTTGRVTLFSAYQVLNTAIAKSKDAFGGVAAIVVDMLKPILEWVLKK----M 591
Query 640 EFLRDGW----EIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIII 695
+ W E + + +V G+ + + L+ ++ S+
Sbjct 592 SIAKGAWLPYAEGLLALFKAQFTVVKGKFQFLRASLNSKCHSLCDLLTTIMSKLLTSVKW 651
Query 696 GGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLM-PLKAPKEIIFLEGETLPTEVLTE 754
G K+ AL G + KG+ + + GLL+ P + E+ L+G+ LT+
Sbjct 652 AGCKVDALYTGTYYYFSRKGVLTEVQLCAKRLGLLLTPKQQKMEVEVLDGDFDAPVTLTD 711
Query 755 EVVLKTGDLQPLEQPTSEAVEAPLV-GTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTF 813
L+ + + + A + LV GT V + + + +D Y + V F
Sbjct 712 ---LELEECTGVLEEVFGASDVKLVKGTLVSLASKLFVRTEDGFLY-RYVKSGGVLGKAF 767
Query 814 TLKGGAPTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFAC 873
L+GG +KVTFGD+ V + +VN ++++ E +D +L++ + + VE GT++ + AC
Sbjct 768 RLRGGGVSKVTFGDEEVHTIPNTVTVNFSYDVCEGLDAILDKVMAPFQVEEGTKLEDLAC 827
Query 874 VVADAVIKTLQPV----SELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYP--P 927
VV AV + L + L P I+L+++ + +++ + E L MY S P
Sbjct 828 VVQKAVYERLSDLFSDCPAELRP--INLEDFLTSECFVYSKDYEKILMPEMYFSLEDAVP 885
Query 928 DEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQT 987
+DE D E+ ++ + ++ WL D
Sbjct 886 VDDEMVDDIED-----------------------------TVEQASDSDDQWLGD----- 911
Query 988 VGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVE 1047
+G+ED TI +V M TP GY K+ ++VYIK ADIV+
Sbjct 912 ----EGAEDCD----NTIQDVDVATSMT-TP----------CGYTKIAEHVYIKCADIVQ 952
Query 1048 EAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSG 1107
EA+ V+VNAANV L HGGGVAGALN+ATNNAMQ ES +YI NG L+ GG +LS
Sbjct 953 EARNYSYAVLVNAANVNLHHGGGVAGALNRATNNAMQKESSEYIKANGSLQPGGHVLLSS 1012
Query 1108 HNLAKH-CLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCV 1166
H LA H LHVVGP+ G+D+ LL + Y + + +L PL+SAGIFG SL V
Sbjct 1013 HGLASHGILHVVGPDKRLGQDLALLDAVYAAYTGFDSVLTPLVSAGIFGFTVEESLCSLV 1072
Query 1167 DTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRK 1226
V Y+ V+D+ LY++ +++ ++ + Q + I E E + S+ +
Sbjct 1073 KNVACTTYVVVYDRQLYERALATSFDVPGPQSSVQHVPAIDWAEA----VEVQESIVDQV 1128
Query 1227 QDDK--KIKACVEEVTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDITFLKKDAP 1284
+ + + L ET EN++ + PD +V+D++
Sbjct 1129 ETPSLGAVDTVDSNADSGLNETARSPENVVGSV-------PDD--VVADVE--------- 1170
Query 1285 YIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKVPTDNYITTYPGQGLNGYTVEEAKT 1344
V D+V++ V +KV D P + TVE+
Sbjct 1171 SCVRDLVRQVV----------------------KKVKRDK----RPPPIVPQQTVEQQPQ 1204
Query 1345 VLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQR 1404
+ +L ++S + M+ +E L+PV ++ A + ++R
Sbjct 1205 EISSPGDCNTVLVDVVS-----------MSFSAMVNFGKEKGLLIPVVIDYPAFLKVLKR 1253
Query 1405 KYKGIKIQEGVVDY-GARFYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAA 1463
+EG+ G FY Y+ + + LN L L+ +P G++ +G L +A
Sbjct 1254 ----FSPKEGLFSSNGYEFYGYSRDKPLHEVSKDLNSLGRPLIMIPFGFIVNGQTLAVSA 1309
Query 1464 RYMRSLKVPATVSVSSPDAVTAYNGYLT---SSSKTPEEHFIETISLAGSYKDWSYSGQS 1520
MR L VP TV V S +V Y Y S T + F+ I L G+ +DW +
Sbjct 1310 VSMRGLTVPHTVVVPSESSVPLYRAYFNGVFSGDTTAVQDFVVDILLNGA-RDWDVLQTT 1368
Query 1521 TQLGIE----FLKRGDKSVYYTSNPTTFHLDGEVI-TFDNLKTLLSLREVR------TIK 1569
+ + KRG+ + + + + + G+V+ F + + E + IK
Sbjct 1369 CTVDRKVYKTICKRGNTYLCF-DDTNLYAITGDVVLKFATVSKARAYLETKLCAPEPLIK 1427
Query 1570 VFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRV 1629
V TTVD IN T +V + +Y Q G + DG D + P + EG Y N + V
Sbjct 1428 VLTTVDGINYSTVLVSTAQSYRAQIGTVFCDGHDWSNKNPMPTDEGTHLYKQDNFSSAEV 1487
Query 1630 EAF-EYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIEL 1688
A EYY D + + R MS + W Y V+G + D+NCYL A+ LQ I++
Sbjct 1488 TAIREYYGVDDSNIIARAMSIRKTVQTWPYTVVDGRVLLAQRDSNCYLNVAISLLQDIDV 1547
Query 1689 KFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVL 1748
F+ P + AY + G +++A T G D +S + H + + +RV+
Sbjct 1548 SFSTPWVCRAYDALKGGNPLPMAEVLIALGKATPGVSDDAHMVLSAVLNHGTV-TARRVM 1606
Query 1749 NVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMS 1808
VC+ CG Q G +A + G++ + V + C CG+ A +Y+ +Q+SP+++MS
Sbjct 1607 QTVCEHCGVSQMVFTGTDACTFYGSVVLDDLYAPVSVVCQCGRPAIRYVSEQKSPWLLMS 1666
Query 1809 APPAQYELK-HGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
P Q L G + A + G GHY + + + D ++S+ K P TD+
Sbjct 1667 CTPTQVPLDTSGIWKTAIVFRGPVTAGHYMYAVNGTLISVYDANTRRRTSDLKLPATDIL 1726
Query 1868 YKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPNASFDN 1927
Y S+T+ K TY LDGV T IDP Y K+ + YFT PI++V P S+D
Sbjct 1727 YGPTSFTSDSKVETYYLDGVKRTTIDPDFSKYVKRGDYYFTTAPIEVVA-APKLVTSYDG 1785
Query 1928 FKF-VCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLL 1986
F C N + A+ N+ K +L +T +P++ GDVVAI + + G+ +
Sbjct 1786 FYLSSCQNPQLAESFNKAINATKTGPMKL-LTMYPNVAGDVVAISDDNVV-AHPYGSLHM 1843
Query 1987 HKPIVWHVNNATNKATYKPNTW-CIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLK 2045
KP+++ +PNTW + L ST V T N++DVL D
Sbjct 1844 GKPVLF---------VTRPNTWKKLVPLLSTVVVNTPNTYDVLAV------------DPL 1882
Query 2046 PVSEEVVENP-TIQKDVLECNVKTTEVVGDIILKPANNS-LKITEEVGHTDLMAAYVDN- 2102
PV+ E E P +++ + +K T V+ P N L +E TDL YV+
Sbjct 1883 PVNNETSEEPISVKAPIPLYGLKATMVLNGTTYVPGNKGHLLCLKEFTLTDLQTFYVEGV 1942
Query 2103 SSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT--NIVTRC 2160
+ K + LS+VLGL+ + VN + + YA L V+T+ +VTR
Sbjct 1943 QPFVLLKASHLSKVLGLRV--SDSSLHVNHLSKGVVYAYAATRLTTRVTTSLLGGLVTRS 2000
Query 2161 LNRV------------CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGK 2208
+ + C + F+ L ++ + +K S IA NT V
Sbjct 2001 VRKTADFVRSTNPGSKCVGLLCLFYQLFMRFWLLVKKP-PIVKVS--GIIAYNTGCGVTT 2057
Query 2209 FCLEASFNYLKSP----NFSKLINII-----IWFLL--LSVCLGSLIYSTAALGVLMSNL 2257
L NYL+S ++S+L+ ++ IWF+ L++C GV +S
Sbjct 2058 CVL----NYLRSRCGNISWSRLLKLLRYMLYIWFVWTCLTIC-----------GVWLSEP 2102
Query 2258 GMPSYCTGYRE--GYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFK 2315
PS T ++ G + + + +C++G+DSLD YP+L Q S
Sbjct 2103 YAPSLVTRFKYFLGIVMPCDYVLVNETGTGWLHHLCMAGMDSLD-YPALRMQQHRYGS-P 2160
Query 2316 WDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMA 2375
++ T ++ E F AY+L+T ++G+ A++ L Y + + NSWL+ + ++++
Sbjct 2161 YNYTYILMLLEAFFAYLLYTPALPIVGILAVLHLIVLYLPIP-LGNSWLVVFLYYIIRLV 2219
Query 2376 PISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFY 2435
P ++M+RMYI A + +K ++HV GCN+ C+MCYK+N A R+EC+T+VNGV+R FY
Sbjct 2220 PFTSMLRMYIVIAFLWLCYKGFLHVRYGCNNVACLMCYKKNVAKRIECSTVVNGVKRMFY 2279
Query 2436 VYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVT 2495
V ANGG FC HNWNCV+CDT+ STFI +VA DLS QFKRPI TD++ Y V SV
Sbjct 2280 VNANGGTHFCTKHNWNCVSCDTYTVDSTFICRQVALDLSAQFKRPIIHTDEAYYEVTSVE 2339
Query 2496 VKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLP-INVIVFDGKSKCEESSA 2554
V+NG ++ YF+ GQ++YER + F N+ L + KG+ P NV+VFD ++ EE++
Sbjct 2340 VRNGYVYCYFESDGQRSYERFPMDAFTNVSKLHYSELKGAAPAFNVLVFDATNRIEENAV 2399
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
K+A++YY+QL C+PILL+D+ +V VGD A +A MF+AY + +++ M+K+K L +
Sbjct 2400 KTAAIYYAQLACKPILLVDKRMVGVVGDDATIARAMFEAYAQNYLLKYSIAMDKVKHLYS 2459
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGFVD--SDVETKDVVECLKLSHQSDIEVTGDSCNN 2672
TA +++ +++++VL F+ + R D SDV+T D+V C++L HQ E T DS NN
Sbjct 2460 TALQQISSGMTVESVLKVFVGSTRAEAKDLESDVDTNDLVSCIRLCHQEGWEWTTDSWNN 2519
Query 2673 YMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSA 2732
+ TY K + ++ ++G + +A+++NA +AK + LIW DF+ LSE +R+Q++ A
Sbjct 2520 LVPTYIKQDTLSTLEVGQFMTANAKYVNANIAKGAAVNLIWRYADFIKLSESMRRQLKVA 2579
Query 2733 AKKNNLPFKLTCATTRQVVNVVTTKIALKGG-KIVNNWLKQLIKVTLVFLFVAAIFYLIT 2791
A+K L +T ++ + V + T + GG + + +W + LI V ++ + + ++ T
Sbjct 2580 ARKTGLNLLVTTSSLKADVPCMVTPFKIIGGHRRIVSWRRVLIHVFMLLVVLNPQWF--T 2637
Query 2792 PVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKAC 2851
P ++M ++ +K ID V RDI S D CFANK + F+ W+S R GSY N + C
Sbjct 2638 PWYIMRP---IEYNVVDFKVIDNAVIRDITSADQCFANKFSAFENWYSNRYGSYVNSRGC 2694
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ V++ VG +VPGLP LR L + AVG++CYTP I Y F TS
Sbjct 2695 PMVVGVVSDIVGSLVPGLPARFLRVGT-TLLPLVNYGLGAVGSVCYTPHYAINYDVFDTS 2753
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
ACVLAA CT+F ASG+ +PYC D +++ + Y+ L+P Y + S I+FP +
Sbjct 2754 ACVLAATCTLFSSASGERMPYCADAALIQNASRYDMLKPHVMYPFYEHSGYIRFPEV-IS 2812
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
V +V T EYC+ G C+ SEAG+C+S RWV+NN Y+R GV+CG A +L NM
Sbjct 2813 AGVHIVRTMAMEYCKVGRCDVSEAGLCMSLQPRWVVNNAYFRQQSGVYCGTSAFDLFMNM 2872
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
P+ P+GA+DI+ SI+ G ++A+VV+ YY +RFRRAFG+YS V+ N L F+++
Sbjct 2873 LLPIFTPVGAVDITTSILMGALLAVVVSMSLYYLLRFRRAFGDYSGVIFTNILAFVLNVI 2932
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
VLCL Y LP +Y++++LY T Y +D++ + H+ +++MF +VP W+T+ YI+ + +
Sbjct 2933 VLCLEGPYPMLPSIYAMVFLYATCYFGSDIACMMHVSFLIMFAGVVPLWVTVLYIVVVLS 2992
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
+H WF S KR V ++F +F++AAL TF+L+KE++L+L+ ++ Y +YLA+
Sbjct 2993 RHILWFASLCTKRTVQVGDLAFHSFQDAALQTFMLDKEVFLRLKREI--SSDAYFKYLAM 3050
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMA 3270
YNKYKY+SG MDT +YREAAC HL AL +SN G D +YQPP+ S+ SA LQ+G +MA
Sbjct 3051 YNKYKYYSGPMDTAAYREAACSHLVMALEKYSNGGGDTIYQPPRCSVASAALQAGLTRMA 3110
Query 3271 FPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFL 3330
PSG VE C+V+V G+ TLNG+WLD+ V CPRHV+C+ +++ NP+Y L +R +N++F
Sbjct 3111 HPSGLVEPCLVKVNYGSMTLNGIWLDNFVICPRHVMCSRDELANPDYPRLSMRAANYDFH 3170
Query 3331 VQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQ 3390
V +RVIGH+M+ +LKL VD NPKTP Y F+R+ GQ S+LACY+G P+GVY
Sbjct 3171 VSQNGHNIRVIGHTMEGSLLKLTVDVNNPKTPAYSFIRVSTGQAMSLLACYDGLPTGVYT 3230
Query 3391 CAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVD 3450
C +R N T++ SFL GSCGS GF ++ V FCY+H +ELP G H GTD G FYGPF D
Sbjct 3231 CTLRSNGTMRASFLCGSCGSPGFVMNGKEVQFCYLHQLELPNGTHTGTDFSGVFYGPFED 3290
Query 3451 RQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHV 3510
+Q Q A D TITVNVLAWLYAAV++G+ WFL + + + +FN A+KY + +T + +
Sbjct 3291 KQVPQLAAPDCTITVNVLAWLYAAVLSGENWFLTKSSISPAEFNNCAVKYMCQSVTSESL 3350
Query 3511 DILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQS 3570
+L PL+A+TGI+V M ++LK LL G GRTI+GS LEDE TP+D+ RQ GV Q
Sbjct 3351 QVLQPLAAKTGISVERMLSALKVLLSAGFCGRTIMGSCSLEDEHTPYDIGRQMLGVKLQG 3410
Query 3571 AVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 3630
+ + T W + + ++L+L+Q QW+ L LP + F + +K
Sbjct 3411 KFQSMFRWTLQWFAIIFVLTILILLQLAQWTFVGALPFTLLLPLIGFVAVCVGFVSLLIK 3470
Query 3631 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 3690
HKH +L ++LLP AY+N Y P +++ + V+ D + V
Sbjct 3471 HKHTYLTVYLLPVAMVTAYYNFQYTPEGVQGYLLSLYNYVNPGRIDVIGTDLLTMLIISV 3530
Query 3691 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 3750
L++ R V D R+W + + +Y + G+A AIS ++SV +NY+GV
Sbjct 3531 ACTLLSVRMVRTDAYSRIWYVCTAVGWLYNCWTGSADTVAISYLTFMVSVFTNYTGVACA 3590
Query 3751 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 3810
++ A+ +V++ P + +C+++ Y +GY CTCYFG+F L+NR FR TLG
Sbjct 3591 SLYAAQFMVWVLKFLDPTILLLYGRFRCVLVCYLLVGYLCTCYFGVFNLINRLFRCTLGN 3650
Query 3811 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSV 3870
Y+Y+VS+QE RYMNS GLLPP NS A LNIKL G+GG P +V+T+QS M+D+KCTSV
Sbjct 3651 YEYVVSSQELRYMNSHGLLPPTNSWQALMLNIKLAGIGGIPIYRVSTIQSNMTDLKCTSV 3710
Query 3871 VLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKL 3930
VLLSVLQQLRVESSSKLWA CV+LHN+IL + TEAFE VSLLSVLLS+ GA+++++L
Sbjct 3711 VLLSVLQQLRVESSSKLWALCVKLHNEILASNSPTEAFEAFVSLLSVLLSLPGAINLDEL 3770
Query 3931 CEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSE 3990
C +L+N + LQA+ASEFS+L SY + AQ+AY+ AVA G + LKK++NVAKS
Sbjct 3771 CSSILENNSVLQAVASEFSNLSSYVDYENAQKAYDTAVATGAPASTVNALKKAMNVAKSV 3830
Query 3991 FDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIIN 4050
D+D A RKLE+M++ AMT MYKQAR+ED+R+KVT+AMQTMLF M+R+LD+DAL+NI+N
Sbjct 3831 LDKDVATTRKLERMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILN 3890
Query 4051 NARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQ 4110
NAR+G VPL +IP T A KL++V+PD++ Y T T TYA + W++ QV DAD K V
Sbjct 3891 NARNGVVPLGVIPRTAANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGKTVN 3950
Query 4111 LSEISMDNSPNLAWPLIVTALR--ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNA 4168
++I+ +NS NLAWPL+VTA R A S VKLQNNEL P +++M+ AG +QTAC D A
Sbjct 3951 ATDITRENSVNLAWPLVVTAQRQQATSPVKLQNNELMPQTVKRMNVVAGVSQTACVTD-A 4009
Query 4169 LAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL 4228
+AYYN TK GR V+A+L+D L +A+ KS G G + ELEPPC+F+ DTPKGP +KYL
Sbjct 4010 VAYYNATKEGRHVMAILADTDGLAFAKVEKSTGDGFVILELEPPCKFMVDTPKGPALKYL 4069
Query 4229 YFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGG 4288
YF KGL NL RG VLG+LA TVRL AG+ATEV +NS++LS C+F+VD YKDYL +GG
Sbjct 4070 YFTKGLKNLCRGTVLGTLACTVRLHAGSATEVASNSSILSLCSFSVDPEATYKDYLDNGG 4129
Query 4289 QPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGK 4348
PI NCVKML HTGTG AIT P+AN+DQESFGGASCCLYCRCHI+HP G C KGK
Sbjct 4130 SPIGNCVKMLTPHTGTGLAITAKPDANIDQESFGGASCCLYCRCHIEHPGASGVCKYKGK 4189
Query 4349 YVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA 4408
+VQIP NDP+GF ++N VC VC MW+GYGC C LRE LQ+ D + FLNRV G S
Sbjct 4190 FVQIPLVGVNDPIGFCIRNVVCAVCNMWQGYGCPCSSLREINLQARD-ECFLNRVRGTSG 4248
Query 4409 -ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRH 4467
ARL P G+G D+V RAFDI N KVAGF LK NCCR+QE D D +DSYFVVKRH
Sbjct 4249 VARLVPLGSGVQPDIVLRAFDICNTKVAGFGLHLKNNCCRYQELDADGTQLDSYFVVKRH 4308
Query 4468 TFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFD 4527
T SNY E+ Y LKDC VA+HDFFKF I+G M PH+SR+RLTKYTMADLVY+LRHFD
Sbjct 4309 TESNYLLEQRCYEKLKDCGVVARHDFFKFNIEGVMTPHVSRERLTKYTMADLVYSLRHFD 4368
Query 4528 EGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDA 4587
NCDTLKEILV CC DYF++KDWYD VENPDI+RVY NLGE VR+A+L V+ D+
Sbjct 4369 NNNCDTLKEILVLRGCCTADYFDRKDWYDPVENPDIIRVYHNLGETVRKAVLSAVKMADS 4428
Query 4588 MRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAES 4647
M G++GVLTLDNQDLNG WYDFGDFI+ G+GV V+D+YYSL MP+ T+T L AE
Sbjct 4429 MVEQGLIGVLTLDNQDLNGQWYDFGDFIEGPAGAGVAVMDTYYSLAMPVYTMTNMLAAEC 4488
Query 4648 HVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNV 4707
HVD D +KP WD+ KYD+T+ + LF +YFKYWD YHPNCV C DDRCILHCANFN+
Sbjct 4489 HVDGDFSKPKRVWDICKYDYTQFKYSLFSKYFKYWDMQYHPNCVACADDRCILHCANFNI 4548
Query 4708 LFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYA 4767
LFS V P TSFGPLV+KI+VDGVPFVVSTGYH+RELGVV NQD+ H+ RLS +ELLVYA
Sbjct 4549 LFSMVLPNTSFGPLVQKIYVDGVPFVVSTGYHYRELGVVMNQDIRQHAQRLSLRELLVYA 4608
Query 4768 ADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSV 4827
ADPAMH A+ N L DKRT C SVAA+T V FQTVKPG FN+DFY+FAV GFFKEGS++
Sbjct 4609 ADPAMHVAASNALADKRTVCMSVAAMTTGVTFQTVKPGQFNEDFYNFAVKCGFFKEGSTI 4668
Query 4828 ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIV 4887
KHFF+AQDGNAAISDYDYYRYNLPTMCDI+QLLF +EVVDKYFDCYDGGC+ A+QV+V
Sbjct 4669 SFKHFFYAQDGNAAISDYDYYRYNLPTMCDIKQLLFSLEVVDKYFDCYDGGCLQASQVVV 4728
Query 4888 NNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRAR 4947
N DKSAGFPFNK+GKARLYY+S+SY DQD LFAYTKRNV+PTITQMNLKYAISAKNRAR
Sbjct 4729 ANYDKSAGFPFNKFGKARLYYESLSYADQDELFAYTKRNVLPTITQMNLKYAISAKNRAR 4788
Query 4948 TVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLM 5007
TVAGVSI STMTNRQFHQK+LKSIAA RGA+VVIGT+KFYGGW+ ML+T+ VENPHLM
Sbjct 4789 TVAGVSIASTMTNRQFHQKMLKSIAAARGASVVIGTTKFYGGWNRMLRTLCEGVENPHLM 4848
Query 5008 GWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYV 5067
GWDYPKCDRAMPN+LRI ASL+LARKH TCC+ S RFYRLANECAQVLSEMV+CGG YV
Sbjct 4849 GWDYPKCDRAMPNLLRIFASLILARKHATCCNASERFYRLANECAQVLSEMVLCGGGFYV 4908
Query 5068 KPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNR 5127
KPGGTSSGD+TTAYANSVFNICQAV+AN+N LS DGNKI YV+ LQ RLY +YR+
Sbjct 4909 KPGGTSSGDSTTAYANSVFNICQAVSANLNTFLSIDGNKIYTTYVQELQRRLYLGIYRSN 4968
Query 5128 DVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMS 5187
VD + V ++Y YLRKHFSMMILSDD VVC+N+ YA +G VA I+ FK +LY+QNNVFMS
Sbjct 4969 TVDNELVLDYYNYLRKHFSMMILSDDGVVCYNADYAQKGYVADIQGFKELLYFQNNVFMS 5028
Query 5188 EAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLM 5247
E+KCW E D+TKGPHEFCSQHTMLV + VYLPYPDPSRILGAGCFVDD++KTDGTLM
Sbjct 5029 ESKCWVEPDITKGPHEFCSQHTMLVDMKGEQVYLPYPDPSRILGAGCFVDDLLKTDGTLM 5088
Query 5248 IERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRY 5307
+ER+VSLAIDAYPLTKHP+ EY +VF YLQYI+KLH+ELTGH+LD YSVML +DN S+Y
Sbjct 5089 MERYVSLAIDAYPLTKHPDPEYQNVFWCYLQYIKKLHEELTGHLLDTYSVMLASDNASKY 5148
Query 5308 WEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVL 5367
WE EFYE MY LQ+VG CV+CNSQTSLRCG CIRRPFLCCKCCYDHV+ST+HKLVL
Sbjct 5149 WEVEFYENMYMESATLQSVGTCVVCNSQTSLRCGGCIRRPFLCCKCCYDHVVSTTHKLVL 5208
Query 5368 SVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNV 5427
SV PYVCN P CDV DVTQLYLGGMSYYC+ H+PPISFPLCANGQVFGLYKN C GS +V
Sbjct 5209 SVTPYVCNNPSCDVADVTQLYLGGMSYYCRDHRPPISFPLCANGQVFGLYKNICTGSPDV 5268
Query 5428 TDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDREL 5487
DFN++ATCDW+N+ DY+LANT TERLKLFAAETL+ATEE K +Y A V+EVLSDREL
Sbjct 5269 ADFNSLATCDWSNSKDYVLANTATERLKLFAAETLRATEENAKQAYASAVVKEVLSDREL 5328
Query 5488 HLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGD 5547
LSWE GK RPPLNRNYVFTG+ +TKNSKVQ+GEY FEKGDYGD V YR +TTYKL VGD
Sbjct 5329 VLSWETGKTRPPLNRNYVFTGFHITKNSKVQLGEYIFEKGDYGDVVNYRSSTTYKLQVGD 5388
Query 5548 YFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGP 5607
YFVLTSH+V PLS+PTL+PQE Y ++ GLYP +N+ + F+SNV +YQ+VGM +Y+T+QGP
Sbjct 5389 YFVLTSHSVQPLSSPTLLPQERYTKLVGLYPAMNVPESFASNVVHYQRVGMSRYTTVQGP 5448
Query 5608 PGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECF 5667
PGTGKSH +IGLALYYPSA+IVYTACSHAAVDALCEKA K LPI++CSRI+PA+ARVECF
Sbjct 5449 PGTGKSHLSIGLALYYPSAKIVYTACSHAAVDALCEKAHKNLPINRCSRIVPAKARVECF 5508
Query 5668 DKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPA 5727
KFKVN QYVF T+NALPETTADI+V DE+SM TNYDLS++NAR+RAKH VY+GDPA
Sbjct 5509 SKFKVNDVGAQYVFSTINALPETTADILVVDEVSMCTNYDLSMINARVRAKHIVYVGDPA 5568
Query 5728 QLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKA 5787
QLPAPRTLLTKGTL PE+FNSVCRLM +GPD+FL TC RCP EIVDTVSALVYD KLKA
Sbjct 5569 QLPAPRTLLTKGTLAPEHFNSVCRLMVAVGPDIFLATCYRCPKEIVDTVSALVYDKKLKA 5628
Query 5788 HKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVAS 5847
+K + +C+K +YKG +THD SSAIN+PQ+G+V+EFL +NP W+ AVFISPYNSQN+VA
Sbjct 5629 NKVTTGECYKCYYKGSVTHDSSSAINKPQLGLVKEFLIKNPKWQSAVFISPYNSQNSVAR 5688
Query 5848 KILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYD 5907
++LGL TQTVDSSQGSE+DYVI+ QT++TAH+ NVNRFNVAITRAK GILC+MSD LY+
Sbjct 5689 RMLGLQTQTVDSSQGSEFDYVIYCQTSDTAHALNVNRFNVAITRAKKGILCVMSDSTLYE 5748
Query 5908 KLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVD 5966
L+FT L++ +Q+E GLFKDC+K L P APT +SV+ KFK E LCV
Sbjct 5749 SLEFTPLDVNDYVKPKMQSEVTVGLFKDCAKA-EPLGPAYAPTFVSVNDKFKLNESLCVH 5807
Query 5967 IPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAV 6026
M Y RLIS MGFK + + GY +FITRE+AIR VR W+GFDVEG HA +
Sbjct 5808 FDTTELQMPYNRLISKMGFKFDLNIPGYSKLFITREQAIREVRGWVGFDVEGAHACGPNI 5867
Query 6027 GTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNV 6086
GTNLPLQ+GFSTGVN V P+GY+DT + + + V +K PPGDQFKHLIPLM KG PW+V
Sbjct 5868 GTNLPLQIGFSTGVNFVVTPSGYIDTESGSRLANVVSKAPPGDQFKHLIPLMRKGEPWSV 5927
Query 6087 VRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTAS 6146
VR +IV+ML DTL +SD V FV WAHGFELT++ YF K+GPER C +C RRAT FS+
Sbjct 5928 VRKRIVEMLCDTLDGVSDTVTFVTWAHGFELTTLHYFAKVGPERKCFMCPRRATLFSSVY 5987
Query 6147 DTYACWHHSI---GFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTR 6203
Y+CW H G D+VYNPF++DVQQWG+ GNLQ NHD C VH AHVASCDAIMTR
Sbjct 5988 GAYSCWSHHRHIGGADFVYNPFLVDVQQWGYVGNLQVNHDNVCDVHKGAHVASCDAIMTR 6047
Query 6204 CLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAI 6263
CLA+H+CF V+W +EYPII +EL IN ACR VQ +V+KAA+ A ++DIGNPKAI
Sbjct 6048 CLAIHDCFCGEVNWDVEYPIIANELAINRACRSVQRVVLKAAVKALHIETIYDIGNPKAI 6107
Query 6264 KCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIV 6323
K W FYD P + +++L Y Y H D+F DG+ +FWNCNVD YP N++V
Sbjct 6108 KVYGVNVNNWNFYDTNPVVE---GVKQLHYVYDVHRDQFKDGLAMFWNCNVDCYPHNALV 6164
Query 6324 CRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESH--- 6380
CRFDTRVLS LNL GC+GGSLYVN+HAFHT AF+K+AFVNLK LPFFYYSD+ CE+
Sbjct 6165 CRFDTRVLSKLNLAGCNGGSLYVNQHAFHTDAFNKNAFVNLKPLPFFYYSDTACENATGV 6224
Query 6381 GKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFD 6440
VS++DYVPLKS CITRCNLGGAVC+ HA+EYR +L++YN M+SAGF+LWV K FD
Sbjct 6225 STNYVSEVDYVPLKSNVCITRCNLGGAVCKKHADEYRNFLESYNTMVSAGFTLWVDKTFD 6284
Query 6441 TYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTT 6500
+NLW+TF +LQSLENVA+NV+ GHF GE+PV+I+N+ +Y K DG D LF N T
Sbjct 6285 VFNLWSTFVKLQSLENVAYNVLKSGHFTAVAGELPVAILNDRLYIKEDGADKLLFTNNTC 6344
Query 6501 LPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIA 6560
LP NVAFELWAKR++ VPEVK+L NLGV N VIWDY+ +AP +T+G+C+ TD+
Sbjct 6345 LPTNVAFELWAKRSVNVVPEVKLLRNLGVTCTYNLVIWDYESNAPLVPNTVGICTYTDLT 6404
Query 6561 KKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI 6620
K + V DGR F +N + + K + + GP AS+NGV +
Sbjct 6405 KLDDQ------VVLVDGRQLDAYSKFCQLKNAIYFSPSKPKCVC-TRGPTHASINGVVVE 6457
Query 6621 GEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLE 6680
T F Y + DG Q + YFTQSR + +F+PR+Q+EIDFL+L F+++Y L
Sbjct 6458 APDRGTAFWYAMRKDGAFVQPTDGYFTQSRTVDDFQPRTQLEIDFLDLEQSCFLDKYDLH 6517
Query 6681 GYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSS 6740
EHIVYG F + +GGLHLLIG +R + + +E + D TV +Y + D T SS
Sbjct 6518 DLGLEHIVYGQFDGT-IGGLHLLIGAVRRKRTAHLVMETVLGTD-TVTSYAVIDQPTASS 6575
Query 6741 KCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSS 6800
K VCSV+D++LDDF+ +IK+QD SVVSKVV+ +D+ FMLWCK G + TFYP+LQ+
Sbjct 6576 KQVCSVVDIILDDFIALIKAQDRSVVSKVVQCCLDFKVFRFMLWCKGGKISTFYPQLQAK 6635
Query 6801 QAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVP 6860
Q W+PG +MP LYK+Q +LE C L NYG +A LP G +MNVAKYTQLCQYLNT +LAVP
Sbjct 6636 QDWKPGYSMPALYKVQNAVLEPCLLHNYGQAARLPSGTLMNVAKYTQLCQYLNTCSLAVP 6695
Query 6861 YNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTAN 6920
MRV+HFGAGSDKGV PGTAVL+QWLP LVD+DL SDADST +G C T + N
Sbjct 6696 AKMRVMHFGAGSDKGVCPGTAVLKQWLPADAYLVDNDLCYCASDADSTYVGSCETFFSVN 6755
Query 6921 KWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYK 6980
KWD I SDMYD +TKN + +N SKEGFFTY+ GFI+ KLALGGS+AIKITEHSW+ADLY
Sbjct 6756 KWDFIFSDMYDARTKNTSGDNTSKEGFFTYLTGFIRSKLALGGSIAIKITEHSWSADLYA 6815
Query 6981 LMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSY 7040
+MGHF WWT F T+VN+SSSEAFLIG NY+G +DG+ MHANY+FWRN+ +QLSSY
Sbjct 6816 IMGHFNWWTCFCTSVNSSSSEAFLIGVNYIGV-GALLDGWQMHANYVFWRNSTVMQLSSY 6874
Query 7041 SLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRE 7082
SL+D+ +FPL+L+GT VMSLKE Q+N+++L+L+ GRLI+R+
Sbjct 6875 SLYDLQRFPLRLKGTPVMSLKEDQLNELVLNLIRAGRLIVRD 6916
>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=rep PE=1 SV=1
Length=7078
Score = 5991 bits (15542), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3040/5978 (51%), Positives = 3999/5978 (67%), Gaps = 202/5978 (3%)
Query 1259 INGNLHPDSATLVSDIDITFLKKDAPYIVGD-VVQEGVLTA-----VVIPTKKAGGTTEM 1312
I G ++ S V ++ P VGD V+ +G A VV P +A +
Sbjct 1156 IAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSL 1215
Query 1313 LAK---ALRKVPTDNYITTYPGQGLNG--------YTVEEAKTVLKKCKSAFYILPSIIS 1361
L+K A+ P +T G+ G Y + EAKT + ++ + S+
Sbjct 1216 LSKCYKAMNAYPL--VVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTI 1273
Query 1362 NEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGAR 1421
+ + L LR + A++ + VC + A ++ K + VD G +
Sbjct 1274 VDIPQSLTFSYDGLRGAIRKAKDYGFTVFVCTDNSANTKVLRNKGVDYTKKFLTVD-GVQ 1332
Query 1422 FYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPD 1481
+Y YTSK T+ ++ N + +++MPLGYV+HGL+L +A +R + VP +++ +
Sbjct 1333 YYCYTSKDTLDDILQQANK-SVGIISMPLGYVSHGLDLIQAGSVVRRVNVPYVCLLANKE 1391
Query 1482 AVTAYNGYLTSSSK--TPEEHFIETISLAGSYKDWSYSG-----QSTQLGIEFLKRGDKS 1534
L S P E FI+ + G Y W Q +L + L D++
Sbjct 1392 Q----EAILMSEDVKLNPSEDFIKHVRTNGGYNSWHLVEGELLVQDLRLN-KLLHWSDQT 1446
Query 1535 VYYTSNPTTFHLDGEVITFDNLKTLLSLREVRT-----IKVFTTVDNINLHTQVVDMSMT 1589
+ Y + + F+ L + + RT I+V TVD +N T V++ T
Sbjct 1447 ICYKDSVFYVVKNSTAFPFETLSACRAYLDSRTTQQLTIEVLVTVDGVNFRTVVLNNKNT 1506
Query 1590 YGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAF-EYYHTTDPSFLGRYMS 1648
Y Q G + +GAD++ P G + Y+ N +A E Y DP+FL R+ S
Sbjct 1507 YRSQLGCVFFNGADISDTIPDEKQNGHSLYLADNLTADETKALKELYGPVDPTFLHRFYS 1566
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQI-ELKFNPPALQDAYYRARAGEA 1707
KWK + + S+K +DNNCYL ++TL + ++KF PALQ A+ + + G++
Sbjct 1567 LKAAVHKWKMVVCDKVRSLKLSDNNCYLNAVIMTLDLLKDIKFVIPALQHAFMKHKGGDS 1626
Query 1708 ANFCALILAYCNKTVGELGDVRETMSYLFQHANLD-SCKRVLNVVCKTCGQQQTTLKGVE 1766
+F ALI+AY N T G D + + A L S + V C CG + L+G++
Sbjct 1627 TDFIALIMAYGNCTFGAPDDASRLLHTVLAKAELCCSARMVWREWCNVCGIKDVVLQGLK 1686
Query 1767 AVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGT---FTC 1823
A Y+G + E + + C CG + + +V+ +P++++S P + + T F
Sbjct 1687 ACCYVGVQTVEDLRARMTYVCQCGGERHRQIVEHTTPWLLLSGTPNEKLVTTSTAPDFVA 1746
Query 1824 ASEYTG-NYQCGHYKHITSKETLYC-IDGALLTKSSEYKGPITDVFYKENSYTTTIKPVT 1881
+ + G GHY H K L D ++K+S++K +TDV + Y++ V
Sbjct 1747 FNVFQGIETAVGHYVHARLKGGLILKFDSGTVSKTSDWKCKVTDVLFPGQKYSSDCNVVR 1806
Query 1882 YKLDGVVCTEIDPKLDNYYKKDNSYFT-EQPIDLVPNQPYPNASFDNFKFVCDNIKFADD 1940
Y LDG TE+DP L +Y KD YFT E P+ P + + N V + + D
Sbjct 1807 YSLDGNFRTEVDPDLSAFYVKDGKYFTSEPPVTYSPATILAGSVYTNSCLVSSDGQPGGD 1866
Query 1941 -----LNQLTGY--KKPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWH 1993
N L G+ KP +++ +F P +GDV+ ++ Y P +K GA KPI+W
Sbjct 1867 AISLSFNNLLGFDSSKPVTKKYTYSFLPKEDGDVLLAEFDTYDPIYKNGAMYKGKPILW- 1925
Query 1994 VNNATNKATY-----KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVS 2048
NKA+Y K N +R ++ P+E N F L E PV
Sbjct 1926 ----VNKASYDTNLNKFNRASLRQIFDVAPIELENKFTPLSVEST------------PVE 1969
Query 2049 EEVVENPTIQKD--VLECNVKTTEVVGDIILKPANNS-LKITEEVGHTDLMAAYVD-NSS 2104
V+ +Q++ +++C V D + A++S + E + DL YVD
Sbjct 1970 PPTVDVVALQQEMTIVKCKGLNKPFVKDNVSFVADDSGTPVVEYLSKEDLHTLYVDPKYQ 2029
Query 2105 LTIKKPNELSRVLGLKTLATHGL---AAVNSVPWDTIANYAKPFLNK----VVSTTTNIV 2157
+ + K N LS +L L T+ + + AA S+ + F K T T V
Sbjct 2030 VIVLKDNVLSSMLRLHTVESGDINVVAASGSLTRKVKLLFRASFYFKEFATRTFTATTAV 2089
Query 2158 TRCLNRV-------------CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTT---IAKN 2201
C+ V C +++ F L L + ++ + +K S T + N
Sbjct 2090 GSCIKSVVRHLGVTKGILTGCFSFVKMLFMLPLAYFSDSKLGTTEVKVSALKTAGVVTGN 2149
Query 2202 TVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSN----- 2256
VK ++ S + L+ ++ + +++ V L S+ + VL S+
Sbjct 2150 VVKQCCTAAVDLSMDKLRRVDWKSTLRLLLMLCTTMVLLSSVYHLYVFNQVLSSDVMFED 2209
Query 2257 --------------LGMPSYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDSLDTY 2301
LG+ S C G Y + + + T+C S C+ CL DS+ Y
Sbjct 2210 AQGLKKFYKEVRAYLGISSACDGLASAY-RANSFDVPTFCANRSAMCNWCLISQDSITHY 2268
Query 2302 PSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISN 2361
P+L+ +Q +S + ++ E LAY+L+T F L LA + FF+ ++
Sbjct 2269 PALKMVQTHLSHYVLNIDWLWFAFETGLAYMLYTSAFNWLLLAGTLHYFFAQTSIFVDWR 2328
Query 2362 SW------LMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKR 2415
S+ WL ++ P++ +VRMY A + + K Y HV++GC + C++CYKR
Sbjct 2329 SYNYAVSSAFWLFTHI----PMAGLVRMYNLLACLWLLRKFYQHVINGCKDTACLLCYKR 2384
Query 2416 NRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSL 2475
NR TRVE +T+V G +R+FY+ ANGG FC+ HNWNCV+CDT G+TFI +EVA DL+
Sbjct 2385 NRLTRVEASTVVCGGKRTFYITANGGISFCRRHNWNCVDCDTAGVGNTFICEEVANDLTT 2444
Query 2476 QFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLR----ANN 2531
+RPIN TD+S Y VDSVTVK + + + GQ YER L F NLD L+
Sbjct 2445 ALRRPINATDRSHYYVDSVTVKETVVQFNYRRDGQPFYERFPLCAFTNLDKLKFKEVCKT 2504
Query 2532 TKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMF 2591
T G N I++D + +ES A+SA VYYSQ++C+ ILL+D +LV+ VGDS+E+A KMF
Sbjct 2505 TTGIPEYNFIIYDSSDRGQESLARSACVYYSQVLCKSILLVDSSLVTSVGDSSEIATKMF 2564
Query 2592 DAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDVETKD 2650
D++VN+F S +NV +KL+ L++TA + + + +VL+TFI AAR V+SDVET +
Sbjct 2565 DSFVNSFVSLYNVTRDKLEKLISTARDGVRRGDNFHSVLTTFIDAARGPAGVESDVETNE 2624
Query 2651 VVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIA 2710
+V+ ++ +H+ DI++T +S NNY+ +Y K ++++ DLG+ IDC+A +N V ++ N A
Sbjct 2625 IVDSVQYAHKHDIQITNESYNNYVPSYVKPDSVSTSDLGSLIDCNAASVNQIVLRNSNGA 2684
Query 2711 LIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNN-- 2768
IWN +M LS+ L++QIR A +K NL F+LT + R N+++ + KIV
Sbjct 2685 CIWNAAAYMKLSDALKRQIRIACRKCNLAFRLTTSKLRANDNILSVR--FTANKIVGGAP 2742
Query 2769 -W--------LKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRD 2819
W LK + T++ A + YL P M + I+ +K +D G+ RD
Sbjct 2743 TWFNALRDFTLKGYVLATIIVFLCAVLMYLCLPTFSMVPVEFYEDRILDFKVLDNGIIRD 2802
Query 2820 IASTDTCFANKHADFDTWFSQR-GGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTN 2878
+ D CFANKH F W+ + GG Y N CPL AVI G +P +P T L N
Sbjct 2803 VNPDDKCFANKHRSFTQWYHEHVGGVYDNSITCPLTVAVIAGVAGARIPDVP-TTLAWVN 2861
Query 2879 GDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNV 2938
+ F+ RVF+ G++CYTP I Y F+ S C+L +ECT+F+DA G+ PYC+D V
Sbjct 2862 NQIIFFVSRVFANTGSVCYTPIDEIPYKSFSDSGCILPSECTMFRDAEGRMTPYCHDPTV 2921
Query 2939 LEGSVAYESLRPDTRYVLMDGSI-IQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVC 2997
L G+ AY +RP RY L DG++ I+FP E ++R+ T ++YCR G+CE ++ GVC
Sbjct 2922 LPGAFAYSQMRPHVRYDLYDGNMFIKFPEVVFESTLRITRTLSTQYCRFGSCEYAQEGVC 2981
Query 2998 VSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVV 3057
++T+G W + ND++ + PGV+CG D ++++ + L QPI ++ S+V G + +
Sbjct 2982 ITTNGSWAIFNDHHLNRPGVYCGSDFIDIVRRLAVSLFQPITYFQLTTSLVLGIGLCAFL 3041
Query 3058 TCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLT 3117
T L YY + +RAF +Y+ + +++ +C Y+ +Y Y TFY T
Sbjct 3042 TLLFYYINKVKRAFADYTQCAVIAVVAAVLNSLCICFVASIPLCIVPYTALYYYATFYFT 3101
Query 3118 NDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV-VF-NGVSFSTF 3175
N+ +F+ H+ W +MF P+VP W+T Y + + +HF+W + + K+ V VF +G +F
Sbjct 3102 NEPAFIMHVSWYIMFGPIVPIWMTCVYTVAMCFRHFFWVLAYFSKKHVEVFTDGKLNCSF 3161
Query 3176 EEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLA 3235
++AA F++NK+ Y LR+ L Y+R+L L+NKYKYFSGAM+T +YREAA CHLA
Sbjct 3162 QDAASNIFVINKDTYAALRNS--LTNDAYSRFLGLFNKYKYFSGAMETAAYREAAACHLA 3219
Query 3236 KALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
KAL +S +GSD+LYQPP SITS VLQSG KM+ PSG VE CMVQVTCG+ TLNGLWL
Sbjct 3220 KALQTYSETGSDLLYQPPNCSITSGVLQSGLVKMSHPSGDVEACMVQVTCGSMTLNGLWL 3279
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQ---AGNVQLRVIGHSMQNCVLKL 3352
D+ V+CPRHV+C ++ + +PNY+ LLI +NH+F VQ LRV+GH+MQ +LKL
Sbjct 3280 DNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVVGHAMQGTLLKL 3339
Query 3353 KVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVG 3412
VD ANP TP Y F ++PG FSVLACYNG P+G + MRPN+TIKGSFL GSCGSVG
Sbjct 3340 TVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCGSCGSVG 3399
Query 3413 FNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLY 3472
+ + ++FCYMH MEL G H G+ +G YG F+D+Q Q TD +VNV+AWLY
Sbjct 3400 YTKEGSVINFCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLY 3459
Query 3473 AAVINGDRWFLNRFTTTLNDFNLVAMKYNY-EPLTQDHVDILGPLSAQTGIAVLDMCASL 3531
AA++NG WF+ T++ FN A+ + E + VD+L + +TG+A+ + ++
Sbjct 3460 AAILNGCAWFVKPNRTSVVSFNEWALANQFTEFVGTQSVDML---AVKTGVAIEQLLYAI 3516
Query 3532 KELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSL 3591
++L G G+ ILGS +LEDEFTP DV Q GV QS V++ GT HWL T++++
Sbjct 3517 QQLY-TGFQGKQILGSTMLEDEFTPEDVNMQIMGVVMQSGVRKVTYGTAHWLFATLVSTY 3575
Query 3592 LVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN 3651
++++Q+T+++L+ +L+E + AF M+ VKHKH FL LFLLP + Y N
Sbjct 3576 VIILQATKFTLWNYLFETIPTQLFPLLFVTMAFVMLLVKHKHTFLTLFLLPVAICLTYAN 3635
Query 3652 MVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARR 3707
+VY P +S ++ + WL + + D +Y S ++L+++ R +
Sbjct 3636 IVYEPTTPISSALIAVANWLAPTNAYMRTTH-TDIGVYISMSLVLVIVVKRLYNPSLSNF 3694
Query 3708 VWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCP 3767
L + + +Y G A I+ + ++TS+Y+ V + LA+ + Y P
Sbjct 3695 ALALCSGVMWLYTYSIGEA-SSPIAYLVFVTTLTSDYTITVFVTVNLAKVCTYAIFAYSP 3753
Query 3768 IFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQG 3827
+ ++ I+L+Y LG+ CTCYFG+F LLN R +GVYD+ VSTQEFR+M +
Sbjct 3754 QLTLVFPEVKMILLLYTCLGFMCTCYFGVFSLLNLKLRAPMGVYDFKVSTQEFRFMTANN 3813
Query 3828 LLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKL 3887
L P+NS +A LN KL+G+GG PCIKVA +QSK++D+KCTSVVLLSVLQQL +E++S+
Sbjct 3814 LTAPRNSWEAMALNFKLIGIGGTPCIKVAAMQSKLTDLKCTSVVLLSVLQQLHLEANSRA 3873
Query 3888 WAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASE 3947
WA CV+ HNDIL A D +EAFEK VSL + L++ G VD++ L ++ D + LQA SE
Sbjct 3874 WAFCVKCHNDILAATDPSEAFEKFVSLFATLMTFSGNVDLDALASDIFDTPSVLQATLSE 3933
Query 3948 FSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMAD 4006
FS L ++A AQ+AY++A+ +GD S VLK L+K++N+AK+ +++D A+ RKLE+MAD
Sbjct 3934 FSHLATFAELEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKNAYEKDKAVARKLERMAD 3993
Query 4007 QAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTT 4066
QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN II+NAR+GC+PL++IPL
Sbjct 3994 QAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIPLSVIPLCA 4053
Query 4067 AAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPL 4126
+ KL VVIPD+ + + YA ALW+I + + D++IV+ S++ +D++ NL WPL
Sbjct 4054 SNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDV-VDSNENLTWPL 4112
Query 4127 IVTALRAN-SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALL 4185
++ RA+ SAVKLQNNE+ P L+ M +AG QT C + ++LAYY +G + ++ALL
Sbjct 4113 VLECTRASTSAVKLQNNEIKPSGLKTMVVSAGQEQTNC-NTSSLAYYEPVQGRKMLMALL 4171
Query 4186 SDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGS 4245
SD LKWAR DG ++ EL+PPC+F+ PKGP+++YLYF+K LNNL+RG VLG
Sbjct 4172 SDNAYLKWARVEGKDGFVSV--ELQPPCKFLIAGPKGPEIRYLYFVKNLNNLHRGQVLGH 4229
Query 4246 LAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTG 4305
+AATVRLQAG+ TE +NS+VLS F VD KAY D++ +GG P+TNCVKML TGTG
Sbjct 4230 IAATVRLQAGSNTEFASNSSVLSLVNFTVDPQKAYLDFVNAGGAPLTNCVKMLTPKTGTG 4289
Query 4306 QAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL 4365
AI+V PE+ DQE++GGAS CLYCR HI+HP+ G C KGK+VQIP C DPVGF L
Sbjct 4290 IAISVKPESTADQETYGGASVCLYCRAHIEHPDVSGVCKYKGKFVQIPAQCVRDPVGFCL 4349
Query 4366 KNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCG-VSAARLTPCGTGTSTDVVY 4424
NT C VC W GYGC+CD LR+ L + +FL RV G + AR+ PC +G STDVV+
Sbjct 4350 SNTPCNVCQYWIGYGCNCDSLRQAALPQSKDSNFLKRVRGSIVNARIEPCSSGLSTDVVF 4409
Query 4425 RAFDI--YNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLL 4482
RAFDI Y KVAG K+ KTN CRF E D+ + +DSYFVVKRHT NY+ E+ Y+LL
Sbjct 4410 RAFDICNYKAKVAGIGKYYKTNTCRFVELDDQGHHLDSYFVVKRHTMENYELEKHCYDLL 4469
Query 4483 KDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYN 4542
+DC AVA HDFF F +D PHI RQRLT+YTM DLVYALRHFD+ N + LK ILV Y
Sbjct 4470 RDCDAVAPHDFFIFDVDKVKTPHIVRQRLTEYTMMDLVYALRHFDQ-NSEVLKAILVKYG 4528
Query 4543 CCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQ 4602
CCD YF K W+DFVENP ++ VY LGERVRQA+L TV+FCD M AG+VGVLTLDNQ
Sbjct 4529 CCDVTYFENKLWFDFVENPSVIGVYHKLGERVRQAILNTVKFCDHMVKAGLVGVLTLDNQ 4588
Query 4603 DLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDL 4662
DLNG WYDFGDF+ T PGSGV +VDSYYS LMP+L++T L AE+H D D KP I+W L
Sbjct 4589 DLNGKWYDFGDFVITQPGSGVAIVDSYYSYLMPVLSMTDCLAAETHRDCDFNKPLIEWPL 4648
Query 4663 LKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLV 4722
+YDFT+ +++LF++YFKYWDQTYH NCVNC DDRC+LHCANFNVLF+ P T FGP+V
Sbjct 4649 TEYDFTDYKVQLFEKYFKYWDQTYHANCVNCTDDRCVLHCANFNVLFAMTMPKTCFGPIV 4708
Query 4723 RKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLD 4782
RKIFVDGVPFVVS GYH++ELG+V N DV+LH RLS KEL++YAADPAMH AS N LD
Sbjct 4709 RKIFVDGVPFVVSCGYHYKELGLVMNMDVSLHRHRLSLKELMMYAADPAMHIASSNAFLD 4768
Query 4783 KRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAI 4842
RT+CFSVAALT + FQTV+PGNFN+DFYDF VSKGFFKEGSSV LKHFFFAQDGNAAI
Sbjct 4769 LRTSCFSVAALTTGLTFQTVRPGNFNQDFYDFVVSKGFFKEGSSVTLKHFFFAQDGNAAI 4828
Query 4843 SDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWG 4902
+DY+YY YNLPTMCDI+Q+LF +EVV+KYF+ YDGGC+NA++V+VNNLDKSAG PFNK+G
Sbjct 4829 TDYNYYSYNLPTMCDIKQMLFCMEVVNKYFEIYDGGCLNASEVVVNNLDKSAGHPFNKFG 4888
Query 4903 KARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQ 4962
KAR+YY+SMSY++QD LFA TKRNVIPT+TQMNLKYAISAKNRARTVAGVSI STMTNRQ
Sbjct 4889 KARVYYESMSYQEQDELFAMTKRNVIPTMTQMNLKYAISAKNRARTVAGVSILSTMTNRQ 4948
Query 4963 FHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNML 5022
+HQK+LKS+AATRGAT VIGT+KFYGGW MLKT+Y DV+NPHLMGWDYPKCDRAMPNM
Sbjct 4949 YHQKMLKSMAATRGATCVIGTTKFYGGWDFMLKTLYKDVDNPHLMGWDYPKCDRAMPNMC 5008
Query 5023 RIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYA 5082
RI ASL+LARKH TCC+ RFYRLANECAQVLSE V+CGG YVKPGGTSSGDATTAYA
Sbjct 5009 RIFASLILARKHGTCCTTRDRFYRLANECAQVLSEYVLCGGGYYVKPGGTSSGDATTAYA 5068
Query 5083 NSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLR 5142
NSVFNI QA TANV+AL+ +GNKI DK V+++Q LY +YR+ D FV+++YA+L
Sbjct 5069 NSVFNILQATTANVSALMGANGNKIVDKEVKDMQFDLYVNVYRSTSPDPKFVDKYYAFLN 5128
Query 5143 KHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPH 5202
KHFSMMILSDD VVC+NS YA++G +A I+NFK LYYQNNVFMSEAKCW ETDL KGPH
Sbjct 5129 KHFSMMILSDDGVVCYNSDYAAKGYIAGIQNFKETLYYQNNVFMSEAKCWVETDLKKGPH 5188
Query 5203 EFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLT 5262
EFCSQHT+ +K GDD +LPYPDPSRIL AGCFVDDIVKTDGTLM+ERFVSLAIDAYPLT
Sbjct 5189 EFCSQHTLYIKDGDDGYFLPYPDPSRILSAGCFVDDIVKTDGTLMVERFVSLAIDAYPLT 5248
Query 5263 KHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTV 5322
KH + EY +VF +YLQYI KL+ +LTGHMLD YSVML DN++++WE FY +Y+ T
Sbjct 5249 KHEDIEYQNVFWVYLQYIEKLYKDLTGHMLDSYSVMLCGDNSAKFWEEAFYRDLYSSPTT 5308
Query 5323 LQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVT 5382
LQAVG+CV+C+SQTSLRCG CIRRPFLCCKCCYDHVI+T HK+VLSV+PYVCNAPGC V+
Sbjct 5309 LQAVGSCVVCHSQTSLRCGTCIRRPFLCCKCCYDHVIATPHKMVLSVSPYVCNAPGCGVS 5368
Query 5383 DVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAG 5442
DVT+LYLGGMSY+C H+P SFPLCANG VFGLYKN C GS ++ +FN +ATCDWT +G
Sbjct 5369 DVTKLYLGGMSYFCVDHRPVCSFPLCANGLVFGLYKNMCTGSPSIVEFNRLATCDWTESG 5428
Query 5443 DYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNR 5502
DY LANT TE LKLFAAETL+ATEE K SY IAT++E++ +R+L L WE GK +PPLNR
Sbjct 5429 DYTLANTTTEPLKLFAAETLRATEEASKQSYAIATIKEIVGERQLLLVWEAGKSKPPLNR 5488
Query 5503 NYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAP 5562
NYVFTGY +TKNSKVQ+GEY FE+ DY DAV Y+ +TTYKL VGD FVLTSH+V L+AP
Sbjct 5489 NYVFTGYHITKNSKVQLGEYIFERIDYSDAVSYKSSTTYKLTVGDIFVLTSHSVATLTAP 5548
Query 5563 TLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALY 5622
T+V QE YV+ITGLYPT+ + +EF+S+VAN+QK G KY T+QGPPGTGKSHFAIGLA+Y
Sbjct 5549 TIVNQERYVKITGLYPTITVPEEFASHVANFQKSGYSKYVTVQGPPGTGKSHFAIGLAIY 5608
Query 5623 YPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFC 5682
YP+AR+VYTACSHAAVDALCEKA KYL I KCSRIIPA+ARVEC+D+FKVN T QY+F
Sbjct 5609 YPTARVVYTACSHAAVDALCEKAFKYLNIAKCSRIIPAKARVECYDRFKVNETNSQYLFS 5668
Query 5683 TVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLE 5742
T+NALPET+ADI+V DE+SM TNYDLS++NAR++AKH VY+GDPAQLPAPRTLLT+GTLE
Sbjct 5669 TINALPETSADILVVDEVSMCTNYDLSIINARIKAKHIVYVGDPAQLPAPRTLLTRGTLE 5728
Query 5743 PEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKG 5802
PE FNSV RLM +GPD+FL C RCP EIV TVSALVY+NKL A K+ S QCFK+ YKG
Sbjct 5729 PENFNSVTRLMCNLGPDIFLSMCYRCPKEIVSTVSALVYNNKLLAKKELSGQCFKILYKG 5788
Query 5803 VITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQG 5862
+THD SSAINRPQ+ V+ F+T NPAW KAVFISPYNSQNAVA +LGL TQTVDSSQG
Sbjct 5789 NVTHDASSAINRPQLTFVKNFITANPAWSKAVFISPYNSQNAVARSMLGLTTQTVDSSQG 5848
Query 5863 SEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVA 5922
SEY YVIF QT +TAH+ N+NRFNVAITRA+ GILC+M+ + L++ L+FT L
Sbjct 5849 SEYQYVIFCQTADTAHANNINRFNVAITRAQKGILCVMTSQALFESLEFTELSFTNYK-- 5906
Query 5923 TLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLIS 5981
LQ++ VTGLFKDCS+ +GL P APT++SVD K+KT + LCV++ +P ++ Y R+IS
Sbjct 5907 -LQSQIVTGLFKDCSRETSGLSPAYAPTYVSVDDKYKTSDELCVNL-NLPANVPYSRVIS 5964
Query 5982 MMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVN 6041
MGFK++ V GYP +FITREEA+R VR+WIGFDVEG HA+R A GTN+PLQLGFSTGVN
Sbjct 5965 RMGFKLDATVPGYPKLFITREEAVRQVRSWIGFDVEGAHASRNACGTNVPLQLGFSTGVN 6024
Query 6042 LVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKN 6101
V P G VDT + ++A+PPPG+QFKHL+PLM+KG W +VR +IVQMLSDTL
Sbjct 6025 FVVQPVGVVDTEWGNMLTGIAARPPPGEQFKHLVPLMHKGAAWPIVRRRIVQMLSDTLDK 6084
Query 6102 LSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYV 6161
LSD FV WAHGFELTS YF KIG E+ CC+C+RRA +S+ +YACW HS G+DYV
Sbjct 6085 LSDYCTFVCWAHGFELTSASYFCKIGKEQKCCMCNRRAAAYSSPLQSYACWTHSCGYDYV 6144
Query 6162 YNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEY 6221
YNPF +DVQQWG+ GNL +NHD YC VH AHVAS DAIMTRCLA+H CF++RVDW IEY
Sbjct 6145 YNPFFVDVQQWGYVGNLATNHDRYCSVHQGAHVASNDAIMTRCLAIHSCFIERVDWDIEY 6204
Query 6222 PIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPC 6281
P I E K+N+ CR V+ VV+AALLA F ++DIGNPK I V V+W ++DAQP
Sbjct 6205 PYISHEKKLNSCCRIVERNVVRAALLAGSFDKVYDIGNPKGIPIVDDPVVDWHYFDAQPL 6264
Query 6282 SDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDG 6341
+ K+++LFY+ S +F DG+CLFWNCNV +YP N+IVCRFDTRV S NLPGCDG
Sbjct 6265 TR---KVQQLFYTEDMAS-RFADGLCLFWNCNVPKYPNNAIVCRFDTRVHSEFNLPGCDG 6320
Query 6342 GSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGK-QVVSDIDYVPLKSATCIT 6400
GSLYVNKHAFHTPA+D SAF +LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT
Sbjct 6321 GSLYVNKHAFHTPAYDVSAFRDLKPLPFFYYSTTPCEVHGNGSMIEDIDYVPLKSAVCIT 6380
Query 6401 RCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFN 6460
CNLGGAVCR HA EYR Y++AYN++ ++GF LW YK FD YNLW+TFT++Q LEN+AFN
Sbjct 6381 ACNLGGAVCRKHATEYREYMEAYNLVSASGFRLWCYKTFDIYNLWSTFTKVQGLENIAFN 6440
Query 6461 VVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPE 6520
V +GHF G +GE+PV+++N+ ++TK D+ +FENKTTLP N+AFEL+AKR ++ P+
Sbjct 6441 FVKQGHFIGVEGELPVAVVNDKIFTKSGVNDICMFENKTTLPTNIAFELYAKRAVRSHPD 6500
Query 6521 VKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVD 6580
K+L+NL DI V+WDY+R +TIGVC TDI IC FD R +
Sbjct 6501 FKLLHNLQADICYKFVLWDYERSNIYGTATIGVCKYTDIDVNSALNIC------FDIRDN 6554
Query 6581 GQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQ---FNYYKKVDGV 6637
G ++ F + N + I++ +K VGP A NG + V Q F YKKV+
Sbjct 6555 GSLEKFMSTPNAIFISDRKIKKYPCMVGPDYAYFNGAIIRDSDVVKQPVKFYLYKKVNNE 6614
Query 6638 VQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQL 6697
E +TQSR+ +F P S ME DFL D FI++Y LE YAFEH+VYGDFSH+ L
Sbjct 6615 FIDPTECIYTQSRSCSDFLPLSDMEKDFLSFDSDVFIKKYGLENYAFEHVVYGDFSHTTL 6674
Query 6698 GGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEI 6757
GGLHLLIGL K+ +E +E+ + ST+ NYFIT+ T + K VCSVIDL LDDFV I
Sbjct 6675 GGLHLLIGLYKKQQEGHIIMEEMLKGSSTIHNYFITETNTAAFKAVCSVIDLKLDDFVMI 6734
Query 6758 IKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQR 6817
+KSQDL VVSKVVKV ID T I FMLWCKDG V+TFYP+LQ+S W+PG AMP+L+K+Q
Sbjct 6735 LKSQDLGVVSKVVKVPIDLTMIEFMLWCKDGQVQTFYPRLQASADWKPGHAMPSLFKVQN 6794
Query 6818 MLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVA 6877
+ LE+C+L NY S +P+G+ MN+AKY QLCQYLNT TLAVP NMRVIHFGAGSDKG+A
Sbjct 6795 VNLERCELANYKQSIPMPRGVHMNIAKYMQLCQYLNTCTLAVPANMRVIHFGAGSDKGIA 6854
Query 6878 PGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNV 6937
PGT+VLRQWLPT +++D+DLN+FVSDAD TL GDC TV + DL+ISDMYDP TKNV
Sbjct 6855 PGTSVLRQWLPTDAIIIDNDLNEFVSDADITLFGDCVTVRVGQQVDLVISDMYDPTTKNV 6914
Query 6938 TKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNA 6997
T N+SK FFTY+C I LALGGSVAIKITEHSW+ +LY+LMG FAWWT F TN NA
Sbjct 6915 TGSNESKALFFTYLCNLINNNLALGGSVAIKITEHSWSVELYELMGKFAWWTVFCTNANA 6974
Query 6998 SSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAV 7057
SSSE FL+G NYLG +E IDG MHANYIFWRN+ P+ LS+YSLFD+SKF LKL+GT V
Sbjct 6975 SSSEGFLLGINYLGTIKENIDGGAMHANYIFWRNSTPMNLSTYSLFDLSKFQLKLKGTPV 7034
Query 7058 MSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
+ LKE QIN++++SLLS+G+L+IR+N+ + +S+DVLVN
Sbjct 7035 LQLKESQINELVISLLSQGKLLIRDNDTLSVSTDVLVN 7072
Score = 275 bits (703), Expect = 1e-71, Method: Compositional matrix adjust.
Identities = 298/1189 (25%), Positives = 516/1189 (43%), Gaps = 143/1189 (12%)
Query 101 GETLGVLVPHVGEIPVAYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQEN 160
G+ +G+ P+ E+ + +LLRK G GG+ Y ++ + + +DF+ +
Sbjct 123 GKPIGMFFPYDIELVTGKQNILLRKYGR---GGYHYTP--FHYERDNTSCPEWMDDFEAD 177
Query 161 WNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCT-LSEQL 219
K++ + L+++L GG T VD CG DG P+ L+A+ G + +
Sbjct 178 PKGKYA----QNLLKKLIGGDVTP-VDQYMCGVDGKPISAYAFLMAKDGITKLADVEADV 232
Query 220 DFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNS 279
G + + + + W+ ER + Y Q+ F I + D P++ F L
Sbjct 233 AARADDEGFITLKNNLYRLVWHVERKDVPYPKQSIFTINSVVQKDGVENTPPHY-FTLGC 291
Query 280 IIKTIQPR----------VEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGET 329
I T+ PR +++K L F G+ S + S ++C CG
Sbjct 292 KILTLTPRNKWSGVSDLSLKQKLLYTFYGK-------ESLENPTYIYHSAFIECGSCGND 344
Query 330 SWQTGDFVKATCEFCGTENLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGP--EHSLAE 386
SW TG+ ++ CG + + G + NA++ CP +HS+A+
Sbjct 345 SWLTGNAIQGFACGCGASYTANDVEVQSSGMIKPNALLCATCPFAKGDSCSSNCKHSVAQ 404
Query 387 ---YHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGS 443
Y +E I T+ FGG ++Y GC Y+VPRA + + + G
Sbjct 405 LVSYLSER-CNVIADSKSFTLIFGGVAYAYFGCEEGTMYFVPRAKSVVS-RIGDSIFTGC 462
Query 444 EGLNDNLLEI----LQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAF 499
G + + +I L++ + ++N VG+F +N+ + IL+ + + + +KG+
Sbjct 463 TGSWNKVTQIANMFLEQTQHSLNFVGEFVVNDVVLAILSGTTTNVDKIRQLLKGVTLDKL 522
Query 500 KQIVESCGNFKVTKGKAKKGAWNIG----EQKSILSPLYAFAS--EAARVVRSIFSRTLE 553
+ + + VT G A N+G + +I +P E+ + V +I +
Sbjct 523 RDYLADY-DVAVTAGPFMDNAINVGGTGLQYAAITAPYVVLTGLGESFKKVATIPYKVCN 581
Query 554 TAQNSV-----RVLQKAAITILD-GISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQ 607
+ ++++ VL + +D G+S +S L D + DL+ V Y ++Q
Sbjct 582 SVKDTLTYYAHSVLYRVFPYDMDSGVSSFSELLFDCV----DLS----VASTYFLVRLLQ 633
Query 608 -LTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
T +++ I + + +LD E + FL D + + A V
Sbjct 634 DKTGDFMSTIITSCQTAVSKLLDTCFEATEATFNFLLDLAGLFRIFLRNAYVYTSQGFVV 693
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKA-LNLGETFVTHSKGLYRKCVKSR- 724
++ V+ L+NK + L + G+ + A + G + G Y CV ++
Sbjct 694 VNGKVSTLVKQVLDLLNKGMQLLHTKVSWAGSNISAVIYSGRESLIFPSGTYY-CVTTKA 752
Query 725 ----EETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDL-----QPLEQPTSEAVE 775
++ +++P + K+ + G PT+ T V + ++ LEQ + +
Sbjct 753 KSVQQDLDVILPGEFSKKQL---GLLQPTDNSTTVSVTVSSNMVETVVGQLEQTNMHSPD 809
Query 776 APLVGTPVCINGLMLLEIKDTEKYCALAP---NMMVTNNTFTLKGGAPTK-VTFGDDTVI 831
+VG V I+ + + K+ + + A P N F LKGGAP K V FG D V
Sbjct 810 V-IVGDYVIISEKLFVRSKEEDGF-AFYPACTNGHAVPTLFRLKGGAPVKKVAFGGDQVH 867
Query 832 EVQGYKSVNITFELDERIDKVL-NEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL 890
EV +SV + + + +D +L + + V+ + EFA VV + V L + +
Sbjct 868 EVAAVRSVTVEYNIHAVLDTLLASSSLRTFVVDKSLSIEEFADVVKEQVSDLLVKLLRGM 927
Query 891 TPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEE---EEFEPSTQY 947
DLD++ A Y F+ G+ +S M S +P + DEE + E EE E
Sbjct 928 PIPDFDLDDFIDAPCYCFNAEGDASWSSTMIFSLHPVECDEECSEVEASDLEEGESECIS 987
Query 948 EYGTE----------DDY-----QGKPL-EFGATSAALQPEEEQEEDWLDDDSQQTVGQQ 991
E TE D++ + PL E + ++Q E + E ++D +Q +
Sbjct 988 ETSTEQVDVSHEISDDEWAAAVDEAFPLDEAEDVTESVQEEAQPVEVPVEDIAQVVIADT 1047
Query 992 DGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIE--------------------------- 1024
+T + VEV PQ+ ++L QTI+
Sbjct 1048 L----QETPVVSDTVEVPPQV-VKLPSEPQTIQPEVKEVAPVYEADTEQTQSVTVKPKRL 1102
Query 1025 -----VNSFSGYLK--LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
V+ S + +T+ V I D ++ AK +V+VNAAN +LKHGGG+AGA+N
Sbjct 1103 RKKRNVDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHGGGIAGAINA 1162
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
A+ A+Q ESD+YI GPL+VG S +L GH+LAK+ LHVVGP+ +D+ LL Y+
Sbjct 1163 ASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSLLSKCYKA 1222
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKL 1186
N + +++ PL+SAGIFG P S + +T V + V +++Y L
Sbjct 1223 MNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSL 1271
>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182
Score = 5976 bits (15503), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3006/5830 (52%), Positives = 3968/5830 (68%), Gaps = 162/5830 (3%)
Query 1391 VCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPL 1450
+C + A ++ + + + VD G ++Y Y+SK + +I N + + MP+
Sbjct 1379 ICTDQSANAKLLKGRGVDLTKKTQTVD-GVKYYLYSSKDPLTDIITAANAC-KGICAMPI 1436
Query 1451 GYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGS 1510
GYVTHGL+L +A + ++ + VP ++S D V N + + +TPE+ FI T+ G
Sbjct 1437 GYVTHGLDLAQAGQQVKKITVPYVCLLASKDQVPILNSDV--AVQTPEQSFINTVIANGG 1494
Query 1511 YKDWSY-SGQSTQLGIEF---LKRGDKSVYYTSNPTTFHLDGEV-ITFDNL---KTLLSL 1562
Y W +G+ G+ + L D+++ Y N + + G++ + FD+L +T L+
Sbjct 1495 YHCWHLVTGELIVKGVSYRKLLNWSDQTICYADN-KFYVVKGQIALPFDSLEKCRTYLTS 1553
Query 1563 R--EVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
R + + + V T+D +N T V++ + TY Q G + G+D++ P G+ Y+
Sbjct 1554 RAAQQKNVDVLVTIDGVNFRTVVLNNTTTYRVQLGSVFYKGSDISDTIPTEKMSGEAVYL 1613
Query 1621 LPN-DDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATA 1679
N + + E Y T D +FL RY S L KKWKY +G+ S+K NNCY+
Sbjct 1614 ADNLSEAEKAVLSEVYGTADTAFLHRYYSLLALVKKWKYTVHDGVKSLKLNSNNCYVNVT 1673
Query 1680 LLTLQQI-ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQH 1738
+L L + E+KF PALQ AY + + G++ F ALI+AY + T GE D + +
Sbjct 1674 MLMLDMLKEIKFIVPALQAAYLKHKGGDSTEFIALIMAYGDCTYGEPDDASRLLHTILSK 1733
Query 1739 ANLDS-CKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYL 1797
A L + K V C CG Q TT G++A +Y+G S ++ + C CG + L
Sbjct 1734 AELTTQAKMVWRQWCNVCGVQDTTTTGLKACIYVGMNSLDELHATHEECCQCGDVRKRQL 1793
Query 1798 VQQESPFVMMSAPPAQYELKHGTFTCASEYTG-------NYQCGHYKHITSKETL-YCID 1849
V+ +P++++S + + + +YT GHY H+ K+ L Y D
Sbjct 1794 VEHNAPWLLLSGLNEAKVMTPTSQSAGPDYTAFNVFQGVETSVGHYLHVRVKDNLLYKYD 1853
Query 1850 GALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTE 1909
L+K+S+ K +TDV+Y + Y+ V Y LDG ++DP L +Y KD YFT+
Sbjct 1854 SGSLSKTSDMKCKMTDVYYPKQRYSADCNVVVYSLDGNTWADVDPDLSAFYMKDGKYFTK 1913
Query 1910 QPI------DLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGY--KKPASRELKVTFFP 1961
+P+ ++ Y N+ + + N L G+ KP S++L +FFP
Sbjct 1914 KPVIEYSPATILSGSVYTNSCLVGHDGTIGSDAISSSFNNLLGFDNSKPVSKKLTYSFFP 1973
Query 1962 DLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVET 2021
D GDV+ +Y Y P +K GA L KPI+W N+ + A K N +R ++ PV
Sbjct 1974 DFEGDVILTEYSTYDPIYKNGAMLHGKPILWVNNSKFDSALNKFNRATLRQVYDIAPVTL 2033
Query 2022 SNSFDVLKSEDAQGMDNLAC-EDLKPVSE-EVVENPTIQKDVLECNVKTTEVVGD---II 2076
N + VL+ Q ++ A ED KP S +V E+ + +++C V D +
Sbjct 2034 ENKYTVLQDNQIQQVEVEAPKEDAKPQSPVQVAEDIDNKLPIIKCKGLKKPFVKDGYSFV 2093
Query 2077 LKPANNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPW 2135
P + + + +G DL A YVD N L + K N S + + T+ L+ + +
Sbjct 2094 NDP--QGVNVIDTLGIDDLRALYVDRNLRLIVLKENNWSALFNIHTVEKGDLSVIAASGS 2151
Query 2136 DT----IANYAKPFLNKVVSTTTNIVT---RCLNRVCTNYMP------YFFTLLLQLC-- 2180
T I A + S T N+ T + L R+ N + F LL L
Sbjct 2152 ITRRVKILLGASSLFAQFASVTVNVTTAMGKALGRMTRNVITNTGIIGQGFALLKMLLIL 2211
Query 2181 --TFTRSTN-SRIKASMPTTIAKNTVKS-VGKFCLEASFNYLKSPNFSKLINIIIWFLLL 2236
TF +S N S +K + V + V K C A+++ L F ++ LL
Sbjct 2212 PFTFWKSKNQSTVKVEVGALRTAGIVTTNVVKQCASAAYDVLVV-KFKRIDWKSTLRLLF 2270
Query 2237 SVC------------------LGSLIYSTAALGVLM------SNLGMPSYCTGYREGYLN 2272
+C L S + A G+L S LG+ S C G E Y N
Sbjct 2271 LICTTGLLLSSLYYLFLFHQVLTSDVMLDGAEGMLATYRELRSYLGIHSLCDGMVEAYRN 2330
Query 2273 STNVTIATYCTG-SIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAY 2331
+ + +C+ S C+ CL G DSL Y + + IQ ++S+ ++ V E+ LAY
Sbjct 2331 -VSYDVNDFCSNRSALCNWCLIGQDSLTRYSAFQMIQTHVTSYVINIDWVWFVMEFALAY 2389
Query 2332 ILFTRFFYVLGLAAIMQLFFSYFA--VHFISNSWLMWLIINLVQMAPISAMVRMYIFFAS 2389
+L+T F VL L Q FFSY V++ S ++L+ V P+ +VR+Y F A
Sbjct 2390 VLYTSTFNVLLLVVSSQYFFSYTGAFVNWRSYNYLVSGYFFCVTHIPLLGLVRIYNFLAC 2449
Query 2390 FYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHN 2449
+++ + Y HV++GC + C++CYKRNR TRVE +T+V G +R+FY+ ANGG FC HN
Sbjct 2450 LWFLRRFYNHVINGCKDTACLLCYKRNRLTRVEASTVVCGSKRTFYIVANGGTSFCCRHN 2509
Query 2450 WNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAG 2509
WNCV+CDT G+TFI +EVA DL+ +R + PTD+S Y V+SVTVK+ + L++ + G
Sbjct 2510 WNCVDCDTAGIGNTFICEEVANDLTTSLRRLVKPTDKSHYYVESVTVKDSVVQLHYSREG 2569
Query 2510 QKTYERHSLSHFVNLDNLRAN---NTKGSLP-INVIVFDGKSKCEESSAKSASVYYSQLM 2565
YER+ L +F NLD L+ T +P N +++D + +E+ A+SA VYYSQ++
Sbjct 2570 ASCYERYPLCYFTNLDKLKFKEVCKTPTGIPEHNFLIYDSSDRGQENLARSACVYYSQVL 2629
Query 2566 CQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVS 2625
+P+LL+D +V+ VGDS E+A KM D+YVN+F S F V +KL LVATA + +
Sbjct 2630 SKPMLLVDSNMVTTVGDSREIASKMLDSYVNSFISLFGVNRDKLDKLVATARDCVKRGDD 2689
Query 2626 LDNVLSTFISAAR-QGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMT 2684
V+ TF AAR V+SDVET +V+ L+ +++ D+++T + NNY+ +Y K +++
Sbjct 2690 FQTVIKTFTDAARGPAGVESDVETSSIVDALQYAYKHDLQLTTEGFNNYVPSYIKPDSVA 2749
Query 2685 PRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTC 2744
DLG ID +A +N ++ N A IWN D+M LS+ L++QIR A +K N+PF+LT
Sbjct 2750 TADLGCLIDLNAASVNQTSIRNANGACIWNSSDYMKLSDSLKRQIRIACRKCNIPFRLTT 2809
Query 2745 ATTRQVVNVVTTKIA---LKGG------KIVNNWLKQLIKVTLVFLFVAAIFYLITPVHV 2795
+ R N+++ K + L GG K+ + K VTLV +A + YL P
Sbjct 2810 SRLRSADNILSVKFSATKLSGGAPKWLLKLRDFTWKSYCVVTLVVFAMAVLSYLCLPAFN 2869
Query 2796 MSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQR-GGSYTNDKACPLI 2854
MS+ + I+ YK ++ G+ RDI +DTCFANK+ F WF++ GG + ND +CP+
Sbjct 2870 MSQVSFHEDRILTYKVVENGIIRDITPSDTCFANKYQSFSKWFNEHYGGLFNNDISCPVT 2929
Query 2855 AAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACV 2914
AVI G VP LP + L F+ RVF++ N+CYTP+ I Y F+ S CV
Sbjct 2930 VAVIAGVAGARVPNLPANVAWVGRQIVL-FVSRVFASSNNVCYTPTAEIPYERFSDSGCV 2988
Query 2915 LAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSI-IQFPNTYLEGSV 2973
LA+ECT+F+DA GK PYCYD VL G+ AY+ ++P RY + D + I+FP E ++
Sbjct 2989 LASECTLFRDAEGKINPYCYDPTVLPGASAYDQMKPHVRYDMYDSDMYIKFPEVVFESTL 3048
Query 2974 RVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTP 3033
R+ T + YCR G+CE + GVC++T+G W + ND+Y + PGV+CG + +++ +
Sbjct 3049 RITKTLATRYCRFGSCEDANEGVCITTNGSWAIYNDHYANKPGVYCGDNYFDIVRRLGLS 3108
Query 3034 LIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLC 3093
L QP+ +S S+ G ++ I +T YY + +RA +Y+ L++ LC
Sbjct 3109 LFQPVTYFQLSTSLALGVMLCIFLTIAFYYVNKVKRALADYTQCAVVAVAAALLNSLCLC 3168
Query 3094 LTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHF 3153
L Y+ +Y Y TFYLT + +F+ H+ W VMF +VP W+ AYI+ + +H
Sbjct 3169 FVVSNPLLVLPYTALYYYATFYLTGEPAFVMHVSWFVMFGTVVPIWMVFAYIVGVCLRHL 3228
Query 3154 YWFFSNYLKRRV-VF-NGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALY 3211
W + + K+ V VF +G +F++AA F++NK+ Y+ LR+ + YNRYL+++
Sbjct 3229 LWVMAYFSKKHVEVFTDGKLNCSFQDAAANIFVINKDTYVALRNSI--TQDSYNRYLSMF 3286
Query 3212 NKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAF 3271
NKYKY+SGAMDT SYREA+ HL KAL +S +GSDVL+QPP S+TS+VLQSG KMA
Sbjct 3287 NKYKYYSGAMDTASYREASAAHLCKALQVYSETGSDVLFQPPNCSVTSSVLQSGLVKMAA 3346
Query 3272 PSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLV 3331
PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+ LL+ K+N +F+V
Sbjct 3347 PSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDALLVSKTNLSFIV 3406
Query 3332 Q---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGV 3388
Q LRV+GH+M +LKL V++ANP+TP Y F ++PG +FSVLACYNG P+GV
Sbjct 3407 QKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFSVLACYNGRPTGV 3466
Query 3389 YQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPF 3448
+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H G +G YG F
Sbjct 3467 FMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHTGCAFDGVMYGAF 3526
Query 3449 VDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY-EPLTQ 3507
DRQ Q +D T+N++AWLYAA++NG WF+ T + FN AM + E +
Sbjct 3527 EDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEWAMSNQFTEFIGT 3586
Query 3508 DHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVT 3567
VD+L + +TG++V + ++ + L G G+TILG+++LEDEFTP DV Q GV
Sbjct 3587 QSVDML---AHKTGVSVEQLLYAI-QTLHKGFQGKTILGNSMLEDEFTPDDVNMQVMGVV 3642
Query 3568 FQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMM 3627
QS VKR G HWL T+L + + +Q T+++++ +L+E L ++ + A M+
Sbjct 3643 MQSGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLTPLVLCVMACVML 3702
Query 3628 FVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCV 3683
VKHKH FL LFLLP+ + Y N+VY P +S ++ + WL+ + D
Sbjct 3703 TVKHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPASVYMRTTH-TDLG 3761
Query 3684 MYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSN 3743
+Y S L ++ R + + L + + Y G+ ++ + ++TS+
Sbjct 3762 VYLSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPLTYLMFLTTLTSD 3820
Query 3744 YSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
Y+ V + +A+ + Y P ++ ++L+Y +GYFCT YFG+F LLN
Sbjct 3821 YTVTVFLAVNVAKFFARVVFLYAPHAGFIFPEVKLVLLMYLAVGYFCTVYFGVFSLLNLK 3880
Query 3804 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMS 3863
R+ LGVYDY VSTQEFRY+ GL P+NS +A +LN+KL+G+GG PCIK+A+VQSK++
Sbjct 3881 LRVPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTPCIKIASVQSKLT 3940
Query 3864 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3923
D+KCTSVVLLSVLQQL +E++SK WA CV+LHNDIL A D TEAF+ V L + L+S
Sbjct 3941 DLKCTSVVLLSVLQQLHLEANSKAWAHCVKLHNDILAATDPTEAFDNFVCLFATLMSFSA 4000
Query 3924 AVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKK 3982
VD+ L ++LD+ + LQA SEFS L SYA AQ +Y++A+ +GD S VLK L+K
Sbjct 4001 NVDLEALASDLLDHPSVLQATLSEFSHLASYAELEAAQSSYQKALNSGDASPQVLKALQK 4060
Query 3983 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4042
++N+AK+ +++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDN
Sbjct 4061 AVNIAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDN 4120
Query 4043 DALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVV 4102
D LN +I+NAR+GCVPL+++PL + KL VVIPD + + +YA ALW+I +
Sbjct 4121 DVLNGVISNARNGCVPLSVVPLCASNKLRVVIPDITIWNKVVTWPSLSYAGALWDISLIN 4180
Query 4103 DADSKIVQLSEISMDNSPNLAWPLIVTALRA-NSAVKLQNNELSPVALRQMSCAAGTTQT 4161
+ D ++V+ S+++ N +L WPL++ RA +SAV LQNNE+ P L+ M +AG
Sbjct 4181 NVDGEVVKSSDVTETNE-SLTWPLVLECTRAASSAVTLQNNEIRPSGLKTMVVSAGIDHA 4239
Query 4162 ACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPK 4221
C + ++LAYY +G + ++ +LS+ LKWA+ DG I EL+PPC+F+ PK
Sbjct 4240 NC-NTSSLAYYEPVEGRKMLMGILSENAHLKWAKVEGRDGFVNI--ELQPPCKFLIAGPK 4296
Query 4222 GPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYK 4281
GP+V+YLYF+K LNNL+RG +LG +AATVRLQAG+ TE NS+VLS F+VD KAY
Sbjct 4297 GPEVRYLYFVKNLNNLHRGQLLGHIAATVRLQAGSNTEFAINSSVLSAVTFSVDPGKAYL 4356
Query 4282 DYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKG 4341
D++ +GG P+TNCVKML TGTG A++V PEAN DQ+++GGAS CLYCR HI+HP+ G
Sbjct 4357 DFVNAGGAPLTNCVKMLTPKTGTGIAVSVKPEANADQDTYGGASVCLYCRAHIEHPDVTG 4416
Query 4342 FCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
C KGK+VQ+P DPVGF L+NT C VC W G+GC+CD LR + + +FLN
Sbjct 4417 VCKFKGKFVQVPLH-IRDPVGFCLQNTPCNVCQFWIGHGCNCDALRGTTIPQSKDSNFLN 4475
Query 4402 RVCG-VSAARLTPCGTGTSTDVVYRAFDI--YNDKVAGFAKFLKTNCCRFQEKDEDDNLI 4458
RV G + AR+ PC +G +TDVV+RAFDI Y KVAG K+ KTN CRF E D++ + +
Sbjct 4476 RVRGSIVNARIEPCASGLTTDVVFRAFDICNYKAKVAGIGKYYKTNTCRFVEVDDEGHRL 4535
Query 4459 DSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMAD 4518
DS+FVVKRHT NY+ E+ Y+L+KDC AVA HDFF F +D PHI RQRLT+YTM D
Sbjct 4536 DSFFVVKRHTMENYELEKRCYDLVKDCDAVAVHDFFIFDVDKVKTPHIVRQRLTEYTMMD 4595
Query 4519 LVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQAL 4578
LVYALRHFD+ NC+ LK ILV Y CCD YF+ K W+DFVENP+++ VY LGER+RQA+
Sbjct 4596 LVYALRHFDQNNCEVLKSILVKYGCCDASYFDNKLWFDFVENPNVISVYHKLGERIRQAV 4655
Query 4579 LKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILT 4638
L TV+FCD M +G+VGVLTLDNQDLNG WYDFGDF+ T PG+GV +VDSYYS LMP+L+
Sbjct 4656 LNTVKFCDQMVKSGLVGVLTLDNQDLNGKWYDFGDFVITQPGAGVAIVDSYYSYLMPVLS 4715
Query 4639 LTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRC 4698
+T L AE+H D DLTKP I+W LL+YD+T+ ++ LF++YFK WDQ YHPNCVNC DDRC
Sbjct 4716 MTNCLAAETHRDCDLTKPLIEWPLLEYDYTDYKIGLFEKYFKXWDQQYHPNCVNCTDDRC 4775
Query 4699 ILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRL 4758
+LHCANFNVLFS P TSFGP+VRKIFVDGVPFV+S GYH++ELG+V N DV+LH RL
Sbjct 4776 VLHCANFNVLFSMTLPGTSFGPIVRKIFVDGVPFVISCGYHYKELGLVMNMDVSLHRHRL 4835
Query 4759 SFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSK 4818
S KEL++YAADPAMH AS + L D RT CFSVAALT + FQTV+PGNFNKDFYDF VSK
Sbjct 4836 SLKELMMYAADPAMHIASASALWDLRTPCFSVAALTTGLTFQTVRPGNFNKDFYDFVVSK 4895
Query 4819 GFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGG 4878
GFFKEGSSV L+HFFFAQDG+AAI+DY YY YNLPTMCDI+Q+LF +EVVD+YF+ YDGG
Sbjct 4896 GFFKEGSSVTLRHFFFAQDGHAAITDYSYYAYNLPTMCDIKQMLFCMEVVDRYFEIYDGG 4955
Query 4879 CINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKY 4938
C+NA++VIVNNLDKSAG PFNK+GKAR+YY+S+SY++QD LFA TKRNV+PTITQMNLKY
Sbjct 4956 CLNASEVIVNNLDKSAGHPFNKFGKARVYYESLSYQEQDELFAMTKRNVLPTITQMNLKY 5015
Query 4939 AISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVY 4998
AISAKNRARTVAGVSI STMTNRQ+HQK+LKS+AATRG+T VIGT+KFYGGW MLKT+Y
Sbjct 5016 AISAKNRARTVAGVSILSTMTNRQYHQKMLKSMAATRGSTCVIGTTKFYGGWDFMLKTLY 5075
Query 4999 SDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEM 5058
DV+NPHLMGWDYPKCDRAMPNM RI ASL+LARKH+TCC+ + RFYRLANECAQVLSE
Sbjct 5076 KDVDNPHLMGWDYPKCDRAMPNMCRIFASLILARKHSTCCTNTDRFYRLANECAQVLSEY 5135
Query 5059 VMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHR 5118
V+CGG YVKPGGTSSGDATTAYANSVFNI QA TANV+AL+ +GN I D+ V+++Q
Sbjct 5136 VLCGGGYYVKPGGTSSGDATTAYANSVFNILQATTANVSALMGANGNTIVDEEVKDMQFE 5195
Query 5119 LYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVL 5178
LY +YR D FV+ +YA+L KHFSMMILSDD VVC+NS YA++G +ASI+NFK L
Sbjct 5196 LYVNVYRKSQPDPKFVDRYYAFLNKHFSMMILSDDGVVCYNSDYATKGYIASIQNFKETL 5255
Query 5179 YYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDD 5238
YYQNNVFMSEAKCW ETDL KGPHEFCSQHT+ +K GDD +LPYPDPSRIL AGCFVDD
Sbjct 5256 YYQNNVFMSEAKCWVETDLKKGPHEFCSQHTLFIKDGDDGYFLPYPDPSRILSAGCFVDD 5315
Query 5239 IVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVM 5298
IVKTDGTLM+ERFVSLAIDAYPLTKH + EY +VF +YLQYI KL+ +LTGHMLD YSVM
Sbjct 5316 IVKTDGTLMVERFVSLAIDAYPLTKHDDPEYQNVFWVYLQYIEKLYKDLTGHMLDSYSVM 5375
Query 5299 LTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHV 5358
L DN++++WE FY +YT T LQAVG+CV+C+SQTSLRCG CIRRPFLCCKCCYDHV
Sbjct 5376 LCGDNSAKFWEESFYRDLYTAPTTLQAVGSCVVCHSQTSLRCGTCIRRPFLCCKCCYDHV 5435
Query 5359 ISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYK 5418
I+T HK+VLSV+PYVCNAPGCDV DVT+LYLGGMSY+C H+P SFPLCANG VFGLYK
Sbjct 5436 IATPHKMVLSVSPYVCNAPGCDVADVTKLYLGGMSYFCIDHRPVCSFPLCANGLVFGLYK 5495
Query 5419 NTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATV 5478
N C GS +VT+FN +ATCDWT +GDY LANT TE LKLFAAETL+ATEE K SY IAT+
Sbjct 5496 NMCTGSPSVTEFNRLATCDWTESGDYTLANTTTEPLKLFAAETLRATEEASKQSYAIATI 5555
Query 5479 REVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGT 5538
+E++ +REL L WE GK +PPLNRNYVFTGY +TKNSKVQ+GEY FE+ DY DAV Y+ +
Sbjct 5556 KEIVGERELLLVWEAGKAKPPLNRNYVFTGYHITKNSKVQLGEYVFERIDYSDAVSYKSS 5615
Query 5539 TTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGM 5598
TTYKL VGD FVLTSH+V L APT+V QE YV+ITGLYPTL + +EF+++VAN+QK G
Sbjct 5616 TTYKLAVGDIFVLTSHSVATLQAPTIVNQERYVKITGLYPTLTVPEEFANHVANFQKAGF 5675
Query 5599 QKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5658
K+ T+QGPPGTGKSHFAIGLA+YYP+AR+VYTACSHAAVDALCEKA KYL I KCSRII
Sbjct 5676 SKFVTVQGPPGTGKSHFAIGLAIYYPTARVVYTACSHAAVDALCEKAFKYLNIAKCSRII 5735
Query 5659 PARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK 5718
PA+ARVEC+D+FKVN T QY+F T+NALPET+ADI+V DE+SM TNYDLSV+NAR++AK
Sbjct 5736 PAKARVECYDQFKVNETNSQYLFSTINALPETSADILVVDEVSMCTNYDLSVINARIKAK 5795
Query 5719 HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSA 5778
H VY+GDPAQLPAPRTLLT+GTLEPE FNSV RLM +GPD+FL C RCP EIV+TVSA
Sbjct 5796 HIVYVGDPAQLPAPRTLLTRGTLEPENFNSVTRLMCNLGPDIFLSVCYRCPEEIVNTVSA 5855
Query 5779 LVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISP 5838
LVY+NKL A K S QCFK+ YKG +THD SSAINRPQ+ V+ F+ NP W KAVFISP
Sbjct 5856 LVYNNKLVAKKPASGQCFKILYKGSVTHDASSAINRPQLNFVKSFIAANPNWSKAVFISP 5915
Query 5839 YNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILC 5898
YNSQNAVA +LGL TQTVDSSQGSEY YVIF QT +TAH+ N+NRFNVA+TRA+ GILC
Sbjct 5916 YNSQNAVARSVLGLTTQTVDSSQGSEYPYVIFCQTADTAHANNINRFNVAVTRAQKGILC 5975
Query 5899 IMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKF 5958
+M+ + L+D L+F + + N LQ++ VTGL+KDCS+ +GLHP APT++SVD K+
Sbjct 5976 VMTSQALFDSLEFAEVSL---NNYKLQSQIVTGLYKDCSRESSGLHPAYAPTYVSVDDKY 6032
Query 5959 KT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVE 6017
KT + LCV++ +P ++ Y R+IS MGFK++ + YP +FITR+EAIR VR+WIGFDVE
Sbjct 6033 KTSDELCVNL-NVPANVPYSRVISRMGFKLDASIPNYPKLFITRDEAIRQVRSWIGFDVE 6091
Query 6018 GCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPL 6077
G HA+R A GTN+PLQLGFSTGVN V P G VDT + + ++A+PPPG+QFKHL+PL
Sbjct 6092 GAHASRNACGTNVPLQLGFSTGVNFVVQPVGVVDTEWGSMLTSIAARPPPGEQFKHLVPL 6151
Query 6078 MYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDR 6137
M KG W +VR +IVQMLSDTL LSD FV WAHGFELTS YF KIG E+ CC+C+R
Sbjct 6152 MNKGAAWPIVRRRIVQMLSDTLDKLSDYCTFVCWAHGFELTSASYFCKIGKEQRCCMCNR 6211
Query 6138 RATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASC 6197
RA+ +S+ +YACW HS G+DYVYNPF +DVQQWG+ GNL +NHD YC VH AHVAS
Sbjct 6212 RASTYSSPLHSYACWSHSSGYDYVYNPFFVDVQQWGYIGNLATNHDRYCSVHQGAHVASN 6271
Query 6198 DAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDI 6257
DA+MTRCLA+H+CF++RV+W I YP I E ++N+ CR V+ VV+AALLA +F ++DI
Sbjct 6272 DAVMTRCLAIHDCFIERVEWDITYPYISHEKRLNSCCRAVERNVVRAALLAGRFERVYDI 6331
Query 6258 GNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRY 6317
GNPK I V V+W +YDAQP S K+++LFY+ + F+DG+CLFWNCNV RY
Sbjct 6332 GNPKGIPIVDDPVVDWHYYDAQPLSK---KVQQLFYT-EDCAKNFSDGLCLFWNCNVPRY 6387
Query 6318 PANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPC 6377
P N+IVCRFDTRV S NLPGCDGGSLYVNKHAFHTPA+D SAF +LK LPFFYYS +PC
Sbjct 6388 PNNAIVCRFDTRVHSEFNLPGCDGGSLYVNKHAFHTPAYDASAFRDLKPLPFFYYSTTPC 6447
Query 6378 ESHGK-QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVY 6436
E HG ++ DIDYVPLKSA CIT CNLGGAVCR HA EYR Y++AYN++ ++GF LW Y
Sbjct 6448 EVHGNGNMLEDIDYVPLKSAVCITACNLGGAVCRKHAAEYRDYMEAYNLVSASGFRLWCY 6507
Query 6437 KQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFE 6496
K FD YNLW+TFT++Q LEN+A+NV+ +GHF G +GE+PV+++N+ +YTK D DV +FE
Sbjct 6508 KTFDVYNLWSTFTKIQGLENIAYNVIKQGHFTGVEGELPVAVVNDKIYTKSDVNDVCIFE 6567
Query 6497 NKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSM 6556
NKTTLP N+AFEL+AKR ++ P+ +L NL VD+ V+WDY+R +TIGVC
Sbjct 6568 NKTTLPTNIAFELYAKRAVRSHPDFNLLRNLEVDVCYKFVLWDYERSNIYGSATIGVCKY 6627
Query 6557 TDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNG 6616
TDI IC FD R +G ++ F + NG+LI++ VK V A NG
Sbjct 6628 TDIDVNSALNIC------FDIRDNGSLERFMSLPNGILISDRKVKNYPCIVSSNYAYFNG 6681
Query 6617 VTLIGEAVKTQ-----------FNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDF 6665
+ +Q F YKKV+ Q +TY+T R + +F P S+ME DF
Sbjct 6682 TLIRDNTGNSQSSDGEVKQPVTFYIYKKVNNEFVQFTDTYYTLGRTVSDFTPVSEMEKDF 6741
Query 6666 LELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDS 6725
L L D FI++YKLE YAFEH+VYGDFS + LGGLHLLIGL K+ +E +E+ + +
Sbjct 6742 LALDSDVFIKKYKLEAYAFEHVVYGDFSRTTLGGLHLLIGLYKKHQEGHIIMEEMLKERA 6801
Query 6726 TVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWC 6785
TV NYF+T++ T S K VCSVIDL LDDFV+IIK+ DLSVVSKVVK+ ID T I FMLWC
Sbjct 6802 TVHNYFVTESNTASFKAVCSVIDLKLDDFVDIIKAMDLSVVSKVVKIPIDLTMIEFMLWC 6861
Query 6786 KDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKY 6845
KDG V+TFYP+LQ+ W+PG+AMP+L+K+Q LE C L NY S +P+G+ MN+AKY
Sbjct 6862 KDGQVQTFYPRLQAINDWKPGLAMPSLFKVQNSNLEPCMLPNYKQSIPMPQGVHMNIAKY 6921
Query 6846 TQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDA 6905
QLCQYLNT T+AVP NMRV+HFGAGSDKGVAPG++VLRQWLPT +L+D+DLN++VSDA
Sbjct 6922 MQLCQYLNTCTIAVPANMRVMHFGAGSDKGVAPGSSVLRQWLPTDAILIDNDLNEYVSDA 6981
Query 6906 DSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSV 6965
D TL GDC TV + DL+ISDMYDP TK V + N++K FF Y+C FI+ LALGGSV
Sbjct 6982 DITLFGDCVTVRVGQQVDLLISDMYDPSTKVVGETNEAKALFFVYLCNFIKNNLALGGSV 7041
Query 6966 AIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHAN 7025
AIKITEHSW+A+LY+LMG FAWWT F TN NASSSE FLIG NYLG+ +E IDG VMHAN
Sbjct 7042 AIKITEHSWSAELYELMGRFAWWTVFCTNANASSSEGFLIGINYLGELKEVIDGNVMHAN 7101
Query 7026 YIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNR 7085
YIFWRNT + LS+YSLFD+S+FPLKL+GT V+ LKE QIN++++SLLS+G+LIIR+N+
Sbjct 7102 YIFWRNTTLMNLSTYSLFDLSRFPLKLKGTPVLQLKESQINELVISLLSQGKLIIRDNDT 7161
Query 7086 VVISSDVLVN 7095
+ +S+DVLVN
Sbjct 7162 LSVSTDVLVN 7171
Score = 180 bits (457), Expect = 4e-43, Method: Compositional matrix adjust.
Identities = 248/1066 (23%), Positives = 444/1066 (42%), Gaps = 91/1066 (9%)
Query 13 HVQLSLPVLQVRDVLVR---GFGDSVEEVLSEARQHLKDGTCGLV--EVEKGVLPQLEQP 67
HV L + D++++ F D E + L G+ L + KG + L P
Sbjct 28 HVSLKASLCDAGDLVLKISPWFMDG-ESAYKHVSEQLSKGSKLLFVPQTLKGFIRHLPGP 86
Query 68 YVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETL-----GVLVPHVGEIPVAYRKVL 122
V++ MV +A G G TL G+ P ++ + L
Sbjct 87 RVYLVERLTGGTYSDPFMVNQLAYQNAAGEGVIGTTLQGKRVGMFFPFDADLVTGEFQFL 146
Query 123 LRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAY 182
LRK KG GG+ + D + PY D + ++ L+++L GG +
Sbjct 147 LRK---KGFGGNRFR------DAPWDYNWTPYSDLMDALEADPCGKYSQSLLKKLVGGDF 197
Query 183 TRYVDNNFCGPDGYPLECIKDLLARAG--KASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
T +D CG +G P+ L+A G K + +E D+ R + + + I W
Sbjct 198 TP-IDQYMCGKNGKPIAEFAALMASEGITKLADVEAEVKSRTDSDRYI-VFKNKLYRIVW 255
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+R + +Y Q+ F + + DT + P F + S I+ I P + +
Sbjct 256 NVQRKDVAYSKQSAFTMNSIVQLDTME-DVPRHSFTIGSEIQVIAPSTAVQANGHLNLKQ 314
Query 301 RSVYPV---ASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKE-GATT 356
R +Y + +E N + S + C CG+ SW TG+ V+ CG + +
Sbjct 315 RLLYAFYGKQAVSEPNYIYHSAYVDCTSCGKGSWLTGNAVQGFACDCGAHYCANDVDLQS 374
Query 357 CGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRT--IAFGGCVFSYV 414
G + +NAV+ CP + E +H+L + + K + G+T + +GG +++Y+
Sbjct 375 SGLVRKNAVLLTTCPCNKDGEC--KHTLPQLVSMMTDKCDVEVVGKTFILTYGGVIYAYM 432
Query 415 GCHNKCAYWVPRASANIG----CNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLN 470
GC +++PRA + + TG G S+ L L++ + IN V +F L
Sbjct 433 GCSGGTMHFIPRAKSCVSKIGDAIFTGCTGTWSKVCETANL-FLERAQHAINFVNEFVLT 491
Query 471 EEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSIL 530
E + +L+ ++S + + ++ + + G + VT G +G N+G
Sbjct 492 ETVVALLSGTTSSIEELRDLCRNATFEKVRDYLTPRG-WIVTMGSYIEGVINVGAAGVCN 550
Query 531 SPLYA-----------FASEAARVVR--SIFSRTLETAQNSV--RVLQKAAITILDGISQ 575
+ L A F AA + S TL+ +S+ RV I ++
Sbjct 551 AALNAPFIVLSGLGESFKKVAATPWKLCSSLRETLDHYADSITYRVF---PYDIPCDVTD 607
Query 576 YSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKF 635
Y+ L+D + T A V Y+ V QLT+ +F + + + +
Sbjct 608 YTALLLDCAVLTGASA---YFVARYVDEKVEQLTNL----VFSSCQSAVAAFVQACMSTY 660
Query 636 KEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIII 695
K +F+ D + ++K +S V + ++ F +++K + L ++
Sbjct 661 KATAKFISDMFTLIKVVSERLYVYTSVGFVVVGDYSSQLLKQFMHILSKAMQLLHTTVSW 720
Query 696 GGAKLKAL--NLGETFVTHSKGLYRKCVKSR---EETGLLMPLK-APKEIIFLE----GE 745
G+KL ++ N ++ V S Y + R ++ L++P + K+I LE
Sbjct 721 AGSKLPSVVYNGRDSLVFPSGTYYCVSTQGRSLQDQFDLVIPGDLSKKQIGILEPTPNST 780
Query 746 TLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCI-NGLMLLEIKDTEK-YCALA 803
T+ ++ T V + G L+P ++ + E V VG V I N + + ++D+E + L
Sbjct 781 TVDKKINTNVVEVVVGQLEPTKEHSPELV----VGDYVIISNKIFVRSVEDSETVFYPLC 836
Query 804 PNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSVNITFELDERIDKVL-NEKCSAYT 861
+ + F LKGGAP K V FG + E+ +SV++ +++ +D +L + + +T
Sbjct 837 TDGKIVPTLFRLKGGAPPKGVKFGGEQTKEITAVRSVSVDYDVHPVLDALLAGSELATFT 896
Query 862 VELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMY 921
VE V +F VV D VI+ L + G DL++++ Y+++ G+ +S M
Sbjct 897 VEKDLPVKDFVDVVKDEVIELLSKLLRGYNVDGFDLEDFADTPCYVYNAEGDLAWSSTMT 956
Query 922 CSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLD 981
S P +E EEE D + E E ++ ED+ + A A+ P E+ + D L
Sbjct 957 FSVNPVEEVEEECDDDYVEDEYLSEEMLVEEDEN-----SWAAAVEAVIPMEDVQLDTLV 1011
Query 982 DDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNS 1027
+ + D +E T VEV +E + V EV S
Sbjct 1012 AEIDVSEPADDVAEQASTEE----VEVPSACVLEASQVANAAEVES 1053
Score = 138 bits (347), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 66/158 (42%), Positives = 102/158 (65%), Gaps = 0/158 (0%)
Query 1031 YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDY 1090
++ L ++V + D + A+ + ++VNAAN +LKHGGG+A A+++A+ +Q ESDDY
Sbjct 1192 HIVLNNDVTLVFGDAIAVARATEDCILVNAANTHLKHGGGIAAAIDRASGGLVQAESDDY 1251
Query 1091 IATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ GPL VG S +L GH LA LHVVGP+ +DIQLLK Y+ FN++ ++++PL+S
Sbjct 1252 VNFYGPLNVGDSTLLKGHGLATGILHVVGPDARANQDIQLLKRCYKAFNKYPLVVSPLIS 1311
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS 1188
AGIF +P SL + V T Y+ V + +Y+ L +
Sbjct 1312 AGIFCVEPRVSLEYLLSVVHTKTYVVVNSEKVYNDLAA 1349
>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126
Score = 5612 bits (14558), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2736/4883 (56%), Positives = 3531/4883 (72%), Gaps = 77/4883 (2%)
Query 2255 SNLGMPSYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDSLDTYPSLETIQITISS 2313
S LG+ + C G Y N T+ + +C+ S+ C CL G DSL Y +L+ +Q I+S
Sbjct 2274 SYLGIRTLCDGLAVEYRN-TSFDVVDFCSNRSVLCQWCLIGQDSLTRYSALQMLQTHITS 2332
Query 2314 FKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFA--VHFISNSWLMWLIINL 2371
+ ++ E+FLAY+L+T F VL L Q FF+Y + V++ + ++++ + L
Sbjct 2333 YVLNIDWIWFALEFFLAYVLYTSSFNVLLLVVTAQYFFAYTSAFVNWRAYNYIVSGLFFL 2392
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
V P+ +VR+Y F A +++ K Y HV++GC + C++CYKRNR TRVE +TIV G +
Sbjct 2393 VTHIPLHGLVRVYNFLACLWFLRKFYSHVINGCKDTACLLCYKRNRLTRVEASTIVCGTK 2452
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R+FY+ ANGG +C HNWNCV CDT G+TFI EVA DL+ +R I PTDQS Y V
Sbjct 2453 RTFYIAANGGTSYCCKHNWNCVECDTAGVGNTFICTEVANDLTTTLRRLIKPTDQSHYYV 2512
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRAN---NTKGSLP-INVIVFDGKS 2547
DSV VK+ + L++++ G YER+ L +F NL+ L+ T +P N +++D
Sbjct 2513 DSVVVKDAVVELHYNRDGSSCYERYPLCYFTNLEKLKFKEVCKTPTGIPEHNFLIYDTND 2572
Query 2548 KCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPME 2607
+ +E+ A+SA VYYSQ++C+P+LL+D LV+ VGDS E+A+KM D+++N+F S F+V +
Sbjct 2573 RGQENLARSACVYYSQVLCKPMLLVDVNLVTTVGDSREIAIKMLDSFINSFISLFSVSRD 2632
Query 2608 KLKTLVATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDVETKDVVECLKLSHQSDIEVT 2666
KL+ L+ TA + + VL TF AAR V+SDVET VV+ L+ +H++DI++T
Sbjct 2633 KLEKLINTARDCVRRGDDFQTVLKTFTDAARGHAGVESDVETTMVVDALQYAHKNDIQLT 2692
Query 2667 GDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLR 2726
+ NNY+ Y K +++ DLG ID A +N ++ N A +WN D+M LS+ +
Sbjct 2693 TECYNNYVPGYIKPDSINTLDLGCLIDLKAASVNQTSMRNANGACVWNSGDYMKLSDSFK 2752
Query 2727 KQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVN---NWLKQLIKVTL----- 2778
+QIR A +K N+PF+LT + R N+++ K + KIV +WL ++ +T+
Sbjct 2753 RQIRIACRKCNIPFRLTTSKLRAADNILSVKFS--ATKIVGGAPSWLLRVRDLTVKGYCI 2810
Query 2779 --VFLF-VAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFD 2835
+F+F VA + + P + ++ I+ YK I+ G+ RDIA D CFANK+ F
Sbjct 2811 LTLFVFTVAVLSWFCLPSYSIATVNFNDDRILTYKVIENGIVRDIAPNDACFANKYGHFS 2870
Query 2836 TWFSQ-RGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGN 2894
WF++ GG Y N CP+ AVI G V +P T L + F+ RVF A N
Sbjct 2871 KWFNENHGGVYRNSVDCPITIAVIAGVAGARVANVPAT-LAWVGRQIVLFVSRVF-ANTN 2928
Query 2895 ICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRY 2954
+C+TP+ I Y F+ S CVL++ECT+F+DA G P+CYD VL G+ +Y ++P RY
Sbjct 2929 VCFTPTNEIPYDTFSDSGCVLSSECTLFRDAEGNLNPFCYDPTVLPGASSYADMKPHVRY 2988
Query 2955 VLMDGSI-IQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRS 3013
+ D + I+FP E ++R+ T ++YCR G+CE S AGVC+ST+G W L N Y +
Sbjct 2989 DMYDSDMYIKFPEVIFESTLRITKTLATQYCRFGSCEESAAGVCISTNGSWALYNQNYST 3048
Query 3014 LPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGE 3073
PG++CG D +++ + L QP+ +S S+ G ++ + +T YY + +RA +
Sbjct 3049 RPGIYCGDDYFDIVRRLAVSLFQPVTYFQLSTSLAMGLVLCVFLTAAFYYINKVKRALAD 3108
Query 3074 YSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFT 3133
Y+ + L++ LC L Y+ +Y Y TFYLT + +F+ HI W VMF
Sbjct 3109 YTQCAVVAVVAALLNSLCLCFIVANPLLVAPYTAMYYYATFYLTGEPAFIMHISWYVMFG 3168
Query 3134 PLVPFWITIAYIICISTKHFYWFFSNYLKRRV-VF-NGVSFSTFEEAALCTFLLNKEMYL 3191
+VP W+ +Y + + +H +W + + K+ V VF +G +F++AA F++ K+ Y+
Sbjct 3169 TVVPIWMLASYTVGVMLRHLFWVLAYFSKKHVDVFTDGKLNCSFQDAASNIFVIGKDTYV 3228
Query 3192 KLRSDVLLPLTQ--YNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVL 3249
LR+ +TQ + RYL+L+NKYKY+SGAMDT SYREA HL KAL +S +GSD+L
Sbjct 3229 ALRN----AITQDSFVRYLSLFNKYKYYSGAMDTASYREACAAHLCKALQTYSETGSDIL 3284
Query 3250 YQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTS 3309
YQPP S+TS+VLQSG KM+ PSG VE C+VQVTCG+ TLNGLWLD+ V+CPRH++C +
Sbjct 3285 YQPPNCSVTSSVLQSGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPA 3344
Query 3310 EDMLNPNYEDLLIRKSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKF 3366
+ + +PNY+ LLI K+NH+F+VQ LRV+ HSM +LKL VD ANP TP Y F
Sbjct 3345 DQLTDPNYDALLISKTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTF 3404
Query 3367 VRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMH 3426
++PG +FSVLACYNG P+GV+ +R N TIKGSFL GSCGSVG+ + ++F YMH
Sbjct 3405 STVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVLNFVYMH 3464
Query 3427 HMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRF 3486
MEL G H G+ +G YG F D+QT Q TD T+NV+AWLYAAV+NG +WF+
Sbjct 3465 QMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPT 3524
Query 3487 TTTLNDFNLVAMKYNY-EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTIL 3545
+ +N A+ + E + +D+L + +TG++V M A+++ L G G+TIL
Sbjct 3525 RVGIVTYNEWALSNQFTEFVGTQSIDML---AHRTGVSVEQMLAAIQSL-HAGFQGKTIL 3580
Query 3546 GSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFF 3605
G + LEDEFTP DV Q GV QS VKR G HWL+ T++ + + ++Q T+++++ +
Sbjct 3581 GQSTLEDEFTPDDVNMQVMGVVMQSGVKRISYGFMHWLMSTLVLAYVSVMQLTKFTMWTY 3640
Query 3606 LYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVM 3661
L+E + A M VKHKH FL LFLLP + Y N+VY P +S ++
Sbjct 3641 LFETIPTQMTPLLFGFMACVMFTVKHKHTFLSLFLLPVALCLTYANIVYEPQTLVSSTLI 3700
Query 3662 RIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKV 3721
+ WL + L D +Y S +L ++ R + L + + Y
Sbjct 3701 AVANWLTPTSVYMRTTHL-DFGLYISLSFVLAIIVRRLYRPSMSNLALALCSGVMWFYTY 3759
Query 3722 YYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIML 3781
G+ I+ I ++TS+Y+ V + LA+ I + Y P ++ ++L
Sbjct 3760 VIGDH-SSPITYLMFITTLTSDYTITVFATVNLAKFISGLVFLYAPHLGFILPEVKLVLL 3818
Query 3782 VYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLN 3841
+Y LGY CT YFG+F LLN R+ LGVYDY VSTQEFR++ GL P+NS +A LN
Sbjct 3819 IYLCLGYMCTMYFGVFSLLNLKLRVPLGVYDYSVSTQEFRFLTGNGLHAPRNSWEALILN 3878
Query 3842 IKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLA 3901
KLLG+GG PCIKVATVQSK++D+KCTSVVLL+VLQQL +ES+SK W+ CV+LHN+IL A
Sbjct 3879 FKLLGIGGTPCIKVATVQSKLTDLKCTSVVLLTVLQQLHLESNSKAWSYCVKLHNEILAA 3938
Query 3902 KDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQ 3961
D TEAFE+ V L + L+S VD++ L ++ +N + LQA +EFS L +YA TAQ
Sbjct 3939 VDPTEAFERFVCLFATLMSFSANVDLDALANDLFENSSVLQATLTEFSHLATYAELETAQ 3998
Query 3962 EAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
+Y++A+ +GD S VLK L+K++NVAK+ +++D A+ RKLE+MA+QAMT MYKQAR+ED
Sbjct 3999 SSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKLERMAEQAMTSMYKQARAED 4058
Query 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
K+AK+ SAMQTMLF M++KLDND LN +I NAR+GCVPL+I+PL + KL VVIPD + +
Sbjct 4059 KKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSIVPLCASNKLRVVIPDISVW 4118
Query 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANS-AVKL 4139
+ + +YA +LW++ + + D+++V+ +++ ++ + +L WPL++ RA+S AVKL
Sbjct 4119 NKVVNWPSVSYAGSLWDVTVINNVDNEVVKPTDV-VETNESLTWPLVIECSRASSSAVKL 4177
Query 4140 QNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKS 4199
QNNE+ P L+ M AG Q C+ +A+AYY +G R V+ LLS+ LKWA+
Sbjct 4178 QNNEIHPKGLKTMVVTAGIDQVNCSS-SAVAYYEPVQGHRMVMGLLSENAHLKWAKVEGK 4236
Query 4200 DGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATE 4259
DG I EL+PPC+F+ PKGP+++YLYF+K LNNL+RG +LG +AATVRLQAG TE
Sbjct 4237 DGF--INIELQPPCKFLIAGPKGPEIRYLYFVKNLNNLHRGQLLGHIAATVRLQAGANTE 4294
Query 4260 VPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQE 4319
+NSTVL+ AFAVD AKAY DY+ SGG P++N VKML TGTG AI+V PEA DQE
Sbjct 4295 FASNSTVLTLVAFAVDPAKAYLDYVGSGGTPLSNYVKMLAPKTGTGVAISVKPEATADQE 4354
Query 4320 SFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGY 4379
++GGAS CLYCR HI+HP+ G C K ++VQIP DPVGF LKN C VC W GY
Sbjct 4355 TYGGASVCLYCRAHIEHPDVSGVCKYKTRFVQIPAH-VRDPVGFLLKNVPCNVCQYWVGY 4413
Query 4380 GCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDK--VAG 4436
GC+CD LR + + +FLNRV G S ARL PC +G +TDVVYRAFDI N K VAG
Sbjct 4414 GCNCDALRNNTVPQSKDTNFLNRVRGSSVNARLEPCSSGLTTDVVYRAFDICNFKARVAG 4473
Query 4437 FAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKF 4496
K+ KTN CRF + D++ + +DSYF+VKRHT SNY+ E+ Y+LLKDC AVA HDFF F
Sbjct 4474 IGKYYKTNTCRFVQVDDEGHKLDSYFIVKRHTMSNYELEKRCYDLLKDCDAVAIHDFFIF 4533
Query 4497 RIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYD 4556
+D PHI RQ LT+YTM DLVYALRHFD+ NC+ LK ILV Y CC+ YF+ K W+D
Sbjct 4534 DVDKTKTPHIVRQSLTEYTMMDLVYALRHFDQNNCEVLKSILVKYGCCEQSYFDNKLWFD 4593
Query 4557 FVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQ 4616
FVENP ++ VY LGER+RQA+L TV+ CD M +G+VGVLTLDNQDLNG WYDFGDF+
Sbjct 4594 FVENPSVIGVYHKLGERIRQAMLNTVKMCDHMVKSGLVGVLTLDNQDLNGKWYDFGDFVI 4653
Query 4617 TTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFD 4676
T PG+GV +VDSYYS LMP+L++T L AE+H D D KP I+W LL+YD+T+ ++ LF+
Sbjct 4654 TQPGAGVAIVDSYYSYLMPVLSMTNCLAAETHKDCDFNKPLIEWLLLEYDYTDYKIGLFN 4713
Query 4677 RYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVST 4736
+YFK+WDQTYHPNCVNC DDRCILHCANFNVLFS V P TSFGP+VRKIFVDGVPF+VS
Sbjct 4714 KYFKHWDQTYHPNCVNCGDDRCILHCANFNVLFSMVLPNTSFGPIVRKIFVDGVPFIVSC 4773
Query 4737 GYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNN 4796
GYH++ELG+V N DVN+H RL+ KEL++YAADPAMH AS + L D RT CFSVAALT
Sbjct 4774 GYHYKELGLVMNMDVNIHRHRLALKELMMYAADPAMHIASASALWDLRTPCFSVAALTTG 4833
Query 4797 VAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMC 4856
+ FQTV+PGNFNKDFYDF VS+GFFKEGSSV LKHFFFAQDG+AAI+DY YY YNLPTM
Sbjct 4834 LTFQTVRPGNFNKDFYDFVVSRGFFKEGSSVTLKHFFFAQDGHAAITDYSYYAYNLPTMV 4893
Query 4857 DIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQ 4916
DI+Q+LF +EVVDKYFD YDGGC+NA++VIVNNLDKSAG PFNK+GKAR+YY+SMSY++Q
Sbjct 4894 DIKQMLFCMEVVDKYFDIYDGGCLNASEVIVNNLDKSAGHPFNKFGKARVYYESMSYQEQ 4953
Query 4917 DALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRG 4976
D LFA TKRNV+PTITQMNLKYAISAKNRARTVAGVSI STMTNRQ+HQK+LKS+AATRG
Sbjct 4954 DELFAVTKRNVLPTITQMNLKYAISAKNRARTVAGVSILSTMTNRQYHQKMLKSMAATRG 5013
Query 4977 ATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTT 5036
AT VIGT+KFYGGW MLKT+Y DVE+PHLMGWDYPKCDRAMPNM RI+ASL+LARKH+T
Sbjct 5014 ATCVIGTTKFYGGWDFMLKTLYKDVESPHLMGWDYPKCDRAMPNMCRILASLILARKHST 5073
Query 5037 CCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANV 5096
CC+ S RFYRLANECAQVLSE V+CGG YVKPGGTSSGDATTAYANSVFNI QA TANV
Sbjct 5074 CCTNSDRFYRLANECAQVLSEYVLCGGGYYVKPGGTSSGDATTAYANSVFNILQATTANV 5133
Query 5097 NALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVV 5156
+AL+S +GN I D+ ++++Q LY +YR D FV+++YA+L KHFSMMILSDD VV
Sbjct 5134 SALMSANGNTIIDREIKDMQFDLYINVYRKVVPDPKFVDKYYAFLNKHFSMMILSDDGVV 5193
Query 5157 CFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGD 5216
C+NS YA++G VASI+NFK LYYQNNVFMSEAKCW ET+L KGPHEFCSQHT+ +K GD
Sbjct 5194 CYNSDYAAKGYVASIQNFKETLYYQNNVFMSEAKCWVETNLEKGPHEFCSQHTLYIKDGD 5253
Query 5217 DYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLY 5276
D +LPYPDPSRIL AGCFVDDIVKTDGT+M+ER+VSLAIDAYPLTKH + EY +VF +Y
Sbjct 5254 DGYFLPYPDPSRILSAGCFVDDIVKTDGTVMMERYVSLAIDAYPLTKHDDTEYQNVFWVY 5313
Query 5277 LQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQT 5336
LQYI KL+ +LTGHMLD YSVML D+++++WE FY +Y+ T LQAVG+CV+C+SQT
Sbjct 5314 LQYIEKLYKDLTGHMLDSYSVMLCGDDSAKFWEEGFYRDLYSSPTTLQAVGSCVVCHSQT 5373
Query 5337 SLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYC 5396
SLRCG CIRRPFLCCKCCYDHVI+T+HK+VLSV+PYVCNAPGCDV+DVT+LYLGGMSYYC
Sbjct 5374 SLRCGTCIRRPFLCCKCCYDHVIATTHKMVLSVSPYVCNAPGCDVSDVTKLYLGGMSYYC 5433
Query 5397 KSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKL 5456
H+P SFPLCANG VFGLYKN C GS ++ +FN +ATCDW+++GDY LANT TE LKL
Sbjct 5434 NDHRPVCSFPLCANGLVFGLYKNMCTGSSSIMEFNRLATCDWSDSGDYTLANTTTEPLKL 5493
Query 5457 FAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSK 5516
FAAETL+ATEE K SY IAT++E++ +REL L WEVGK +PPLNRNYVFTGY +TKNSK
Sbjct 5494 FAAETLRATEEASKQSYAIATIKEIVGERELILVWEVGKSKPPLNRNYVFTGYHLTKNSK 5553
Query 5517 VQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGL 5576
VQ+GEY FE+ DY DAV Y+ +TTYKL VGD FVLTSH+V LSAPT+V QE Y++ITG+
Sbjct 5554 VQLGEYVFERIDYSDAVSYKSSTTYKLAVGDIFVLTSHSVATLSAPTIVNQERYLKITGI 5613
Query 5577 YPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHA 5636
YPT+ + +EF+++V N+QK G KY T+QGPPGTGKSHFAIGLA+YYP+ARIVYTACSHA
Sbjct 5614 YPTITVPEEFANHVVNFQKAGFSKYVTVQGPPGTGKSHFAIGLAIYYPTARIVYTACSHA 5673
Query 5637 AVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVV 5696
AVDALC KA KYL I KCSRIIPA+ARVEC+D+FKVN T QY+F TVNALPE + DI+V
Sbjct 5674 AVDALCAKAFKYLNIAKCSRIIPAKARVECYDRFKVNDTNAQYLFSTVNALPEISVDILV 5733
Query 5697 FDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTI 5756
DE+SM TNYDLS++N+R++AKH VY+GDPAQLPAPRTLLT+GTLEPE FNSV RLM +
Sbjct 5734 VDEVSMCTNYDLSIINSRVKAKHIVYVGDPAQLPAPRTLLTRGTLEPENFNSVTRLMCNL 5793
Query 5757 GPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQ 5816
GPD+FL C RCP EIV+TVSALVY+NKL A KD S QCFK+ +KG +THD SSAINRPQ
Sbjct 5794 GPDIFLSVCYRCPKEIVNTVSALVYNNKLSAKKDASGQCFKILFKGSVTHDASSAINRPQ 5853
Query 5817 IGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTET 5876
+ V+ F+ NP W KAVFISPYNSQNAVA +LGL TQTVDSSQGSEY YVIF QT +T
Sbjct 5854 LNFVKTFIAANPNWSKAVFISPYNSQNAVARSMLGLTTQTVDSSQGSEYPYVIFCQTADT 5913
Query 5877 AHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDC 5936
AH+ N+NRFNVA+TRA+ GILC+M+ + L+D L+F L + N LQ++ VTGLFKDC
Sbjct 5914 AHANNLNRFNVAVTRAQKGILCVMTSQVLFDSLEFAELSL---NNYKLQSQIVTGLFKDC 5970
Query 5937 SKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYP 5995
S+ GL P APT+LSVD K+K T+ LCV++ I ++TY R+IS MGFK++ + GYP
Sbjct 5971 SREDVGLPPAYAPTYLSVDAKYKTTDELCVNL-NITPNVTYSRVISRMGFKLDATIPGYP 6029
Query 5996 NMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNN 6055
+FITR+EAIR VR+WIGFDVEG HA+R A GTN+PLQLGFSTGVN V P G VDT
Sbjct 6030 KLFITRDEAIRQVRSWIGFDVEGAHASRNACGTNVPLQLGFSTGVNFVVQPVGVVDTEWG 6089
Query 6056 TDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGF 6115
+ + +SA+PPPG+QFKHL+PLM KG W +VR +IVQMLSDTL LSD FV WAHGF
Sbjct 6090 SMLTTISARPPPGEQFKHLVPLMNKGATWPIVRRRIVQMLSDTLDKLSDYCTFVCWAHGF 6149
Query 6116 ELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFT 6175
ELTS YF KIG E+ CC+C RRA+ FS+ +YACW HS G+DYVYNPF +DVQQWG+
Sbjct 6150 ELTSASYFCKIGKEQRCCMCSRRASTFSSPLQSYACWSHSSGYDYVYNPFFVDVQQWGYV 6209
Query 6176 GNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACR 6235
GNL +NHD YC +H AHVAS DAIMTRCLA+++CF++RVDW + YP I E K+N+ CR
Sbjct 6210 GNLATNHDRYCGIHAGAHVASSDAIMTRCLAIYDCFIERVDWDVTYPYISHEQKLNSCCR 6269
Query 6236 KVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSY 6295
V+ VV++A+L+ KF ++DIGNPK I + + VEW FYDAQP S+ K+++LFY+
Sbjct 6270 TVERNVVRSAVLSGKFDKIYDIGNPKGIPIISEP-VEWHFYDAQPLSN---KVKKLFYTD 6325
Query 6296 ATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPA 6355
+ +F DG+CLFWNCNV +YP+N++VCRFDTRV S NLPGC+GGSLYVNKHAFHTPA
Sbjct 6326 DV-AKQFEDGLCLFWNCNVSKYPSNAVVCRFDTRVHSEFNLPGCNGGSLYVNKHAFHTPA 6384
Query 6356 FDKSAFVNLKQLPFFYYSDSPCESHGK-QVVSDIDYVPLKSATCITRCNLGGAVCRHHAN 6414
+D +AF +LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT CNLGGAVCR HA
Sbjct 6385 YDINAFRDLKPLPFFYYSTTPCEVHGSGNMLEDIDYVPLKSAVCITACNLGGAVCRKHAA 6444
Query 6415 EYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEV 6474
EYR Y++AYN++ +AGF LWVYK FD YNLW+TF ++Q LEN+AFNV+ +GHF G GE+
Sbjct 6445 EYRDYMEAYNIVSAAGFRLWVYKTFDIYNLWSTFVKVQGLENIAFNVIKQGHFTGVDGEL 6504
Query 6475 PVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAAN 6534
PV+++N+ ++TK DV +F+N+T LP NVAFEL+AKR ++ P++ +L NL VD+ N
Sbjct 6505 PVAVVNDKIFTKNGTDDVCIFKNETALPTNVAFELYAKRAVRSHPDLNLLRNLEVDVCYN 6564
Query 6535 TVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVL 6594
V+WDY R+ +TIGVC TDI P +C FD R G ++ F + NGVL
Sbjct 6565 FVLWDYDRNNIYGTTTIGVCKYTDIDVNPNLNMC------FDIRDKGSLERFMSMPNGVL 6618
Query 6595 ITEGSVKGLQPSVGPKQASLNGVTL--IGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNL 6652
I++ +K +GPK A NG L I F YKKV+ +T++T R +
Sbjct 6619 ISDRKIKNYPCIIGPKHAYFNGAILRNIDAKQPITFYLYKKVNNEFVSFSDTFYTCGRTV 6678
Query 6653 QEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKE 6712
+F + ME DFL L D FI++Y LE YAFEH+VYGDFSH+ LGGLHLLIGL K+ ++
Sbjct 6679 NDFTALTPMEEDFLVLDSDVFIKKYSLEDYAFEHVVYGDFSHTTLGGLHLLIGLYKKMRD 6738
Query 6713 SPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKV 6772
+E+ + +TV NYFITD+ T S K VCSVIDL LDDFV IIK DL VVSKVVKV
Sbjct 6739 GHILMEEMLKDRATVHNYFITDSNTASYKAVCSVIDLRLDDFVNIIKEMDLDVVSKVVKV 6798
Query 6773 TIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSA 6832
ID T I FMLWCKDG V+TFYP+LQ++ W+PG+ MP+L+K+Q+M LE C L NY S
Sbjct 6799 PIDLTMIEFMLWCKDGKVQTFYPRLQATNDWKPGLTMPSLFKVQQMNLEPCLLANYKQSI 6858
Query 6833 TLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTL 6892
+P G+ MNVAKY QLCQYLNT TLAVP NMRVIHFGAG +KGVAPGT+VLRQWLP +
Sbjct 6859 PMPNGVHMNVAKYMQLCQYLNTCTLAVPANMRVIHFGAGCEKGVAPGTSVLRQWLPLDAV 6918
Query 6893 LVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYIC 6952
L+D+DLN+FVSDAD T+ GDC TVH + DL+ISDMYDP TK V + N +K FF Y+C
Sbjct 6919 LIDNDLNEFVSDADITIFGDCVTVHVGQQVDLLISDMYDPCTKAVGEVNQTKALFFVYLC 6978
Query 6953 GFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGK 7012
FI+ LALGGSVAIKITEHSW+ADLYK+MG FA+WT F TN NASSSE FLIG N+LG+
Sbjct 6979 NFIKNNLALGGSVAIKITEHSWSADLYKIMGRFAYWTVFCTNANASSSEGFLIGINFLGE 7038
Query 7013 PREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSL 7072
+E+IDG VMHANYIFWRN+ P+ LS+YSLFD+S+FPLKL+GT V+ LKE QIN++++SL
Sbjct 7039 LKEEIDGNVMHANYIFWRNSTPMNLSTYSLFDLSRFPLKLKGTPVLQLKESQINELVISL 7098
Query 7073 LSKGRLIIRENNRVVISSDVLVN 7095
LS+G+L+IR+N+ + +S+DVLVN
Sbjct 7099 LSQGKLLIRDNDTLNVSTDVLVN 7121
Score = 302 bits (774), Expect = 6e-80, Method: Compositional matrix adjust.
Identities = 225/771 (29%), Positives = 367/771 (48%), Gaps = 46/771 (6%)
Query 1391 VCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPL 1450
+C E A V ++ K + VD G +Y Y+++ + +I N + MP
Sbjct 1352 ICTEYSANVKFLRTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGC-PGICAMPF 1409
Query 1451 GYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGS 1510
GYVTHGL+L ++ Y+R +KVP ++S + + N + + +TPE FI ++ G
Sbjct 1410 GYVTHGLDLAQSGNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGG 1467
Query 1511 YKDWSY-SGQSTQLGI---EFLKRGDKSVYYTSNPTTFHLDGEVITFDNL---KTLLSLR 1563
Y W SG + + L +++ Y N + + F +L + L+ R
Sbjct 1468 YHSWHLVSGDLIVKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFSDLEACRAYLTSR 1527
Query 1564 EVR--TIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVL 1621
+ I+V T+D +N T +++ + T+ +Q G T+ G D++ P G++ +V
Sbjct 1528 AAQQVNIEVLVTIDGVNFRTVILNDATTFRKQLGATFYKGVDISDALPTVKMGGESLFVA 1587
Query 1622 PN-DDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
N ++ V EYY T+D +FL RY S ++WK+ +G+ S+K ++ NCY+ +
Sbjct 1588 DNLSESEEVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATI 1647
Query 1681 LTLQQI-ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHA 1739
+ + + ++KF PALQ+AY R + G+ +F ALI+AY + T D + + L A
Sbjct 1648 MMIDMLHDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKA 1707
Query 1740 NLD-SCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLV 1798
L S K V C CG + G+ A +Y G S E+ + C CG + LV
Sbjct 1708 ELTVSAKMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLV 1767
Query 1799 QQESPFVMMSAPPAQYELKHGTFTCASEYTGNY------QCGHYKHITSKETL-YCIDGA 1851
+ +P++++S E+K T T N GHY H+ K+ L Y D
Sbjct 1768 EHSTPWLLVSG---LNEVKVSTSTDPVYRAFNVFQGVETSVGHYVHVRVKDGLFYKYDSG 1824
Query 1852 LLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQP 1911
LTK+S+ K +T V+Y + YT V Y LDGV E++P L NYY KD Y+T +P
Sbjct 1825 SLTKTSDMKCKMTSVWYPKVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKP 1884
Query 1912 -IDLVPNQPYPNASFDNFKFV-CDNIKFADDL----NQLTGYK--KPASRELKVTFFPDL 1963
I P P + + N V D +D + N L G+ KP S++L + P+
Sbjct 1885 TIKYSPATILPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNE 1944
Query 1964 NGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSN 2023
+GDV+ ++ +Y P +KKG L KPI+W N + A KPN +R L+ P+ N
Sbjct 1945 DGDVLLSEFNNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDN 2004
Query 2024 SFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTE---VVGDIILKPA 2080
+ VL+ +Q + E PV E+V + ++E K V G+
Sbjct 2005 KYTVLQDNTSQLI-----EPNVPVVEDV---SITTRKLIEVKCKGLNKPFVKGNFSFVND 2056
Query 2081 NNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLATHGLAAV 2130
N + + + +G T+L A YVD N+ + + N S + L T+ + L V
Sbjct 2057 PNGVTVVDTLGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVESGDLQIV 2107
Score = 172 bits (437), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 228/972 (23%), Positives = 407/972 (42%), Gaps = 88/972 (9%)
Query 8 FNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEVLSEARQHLKD-GTCGLVEVE-KGV 60
+NEK HV ++P+ D+ L F D E ++ LK+ G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTEDMASKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETL-----GVLVPHVGEIP 115
+ L P V++ H +V +A + + TL G+ P+ +
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDHVGAAMMRTTLNVKPLGMFFPYDSSLE 139
Query 116 VAYRKVLLRKNGNKGAGGHSYGADLKS---FDLGDELGTDPYEDFQENWNTKHSSGVTRE 172
LLRKNG G D K ++ D+L DP + +N
Sbjct 140 TGEHTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSE-QLDF---IDTKRGV 228
L+++L GG VD CG +G P+ ++A+ G TL++ ++D +D+ R +
Sbjct 188 LLKKLIGGDCIP-VDQYMCGKNGKPIADYAKIVAKEGLT--TLADIEVDVKSRMDSDRFI 244
Query 229 YCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQP-- 286
+ + + W R Y QT F + + D P F + S I + P
Sbjct 245 -VLNKKLYRVVWNVTRRNVPYSKQTAFTVVSVIQCDD-KESVPEHTFTIGSQILMVSPLK 302
Query 287 RVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGT 346
K + + + Y + + + S + C+ CG +W TG+ ++ CG
Sbjct 303 ATNNKNFNLKQRLLHTFYGKEAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGA 362
Query 347 ENLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGR--T 403
+ + G +P+NA+ CP +N H+ A+ ++ K + GG+ T
Sbjct 363 NYSANDVDLQSSGLVPKNALFLANCPCANNGAC--SHNAAQVYSILDGKACVEVGGKSFT 420
Query 404 IAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEKV 459
+ FGG V++Y+GC + Y+VPRA + + + G G D ++E L+K +
Sbjct 421 LTFGGVVYAYMGCCDGTMYFVPRAKSCVS-RIGDAIFTGCTGTWDKVVETANLFLEKAQH 479
Query 460 NINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN--FKVTKGKAK 517
++N F L E ++LA S +TS F E +++++ + N F VT G
Sbjct 480 SLNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDYI 536
Query 518 KGAWNIGE----QKSILSPLYAFA--SEAARVVRSIFSRTLETAQNSVRVLQKAAITILD 571
+ A NIG +I +P AF E+ + V +I + N L I+
Sbjct 537 RDAINIGANGVCNATINAPFIAFTGLGESFKKVAAI---PWKICSNLKSALDYYCSNIMF 593
Query 572 GISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYE----KLKPV 627
+ Y + D F L + +A + V++ + + GTV L
Sbjct 594 RVFPYDIP-CDVNDFVELLLDCGKLTVA-TSYFVLRYLDEKFDTVLGTVSNACQTALSSF 651
Query 628 LDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLA 687
L+ + F+ D +++ K + V A+ + VQ +++K +
Sbjct 652 LNACVAASRATAGFISDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLDIMSKAMK 711
Query 688 LCADSIIIGGAKLKALNL-GETFVTHSKGLYRKCVKSREET-----GLLMPLKAPKEIIF 741
L ++ G KL A+ G + + G Y C+ ++ +T L++P K+ +
Sbjct 712 LLHTNVSWAGTKLSAIIYEGREALLFNSGTYF-CLSTKAKTLQDQMNLVLPGDYNKKTLG 770
Query 742 L-----EGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDT 796
+ +T+ + V + G L +PT+E + +VG V ++ + + D
Sbjct 771 ILDPVPNADTIDVTANSTVVDVVHGQL----EPTNEHGPSMIVGNYVLVSDKLFVRTDDE 826
Query 797 EKYCALAPNMMVTNNTFTLKGGAPT-KVTFGDDTVIEVQGYKSVNITFELDERIDKVL-N 854
E Y L N V + F LKGG P+ KVTFGD +EV Y+SV+IT+++ +D +L +
Sbjct 827 EFY-PLCINGKVVSTLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPVLDALLSS 885
Query 855 EKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEF 914
K + +TVE V +F V+ D V+ L P+ G D++++ Y++++ G+
Sbjct 886 SKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYVYNQDGDC 945
Query 915 KLASHMYCSFYP 926
+S+M S P
Sbjct 946 AWSSNMTFSINP 957
Score = 128 bits (322), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 71/176 (40%), Positives = 107/176 (61%), Gaps = 8/176 (5%)
Query 991 QDGSEDNQT-------TTIQTIVE-VQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKN 1042
QD + +NQ T +T VE VQP+ ++ + ++ S + + ++V +
Sbjct 1117 QDEASENQVHQVPDLQCTSETKVEIVQPRQDLRPRRLRKSKVDLSKYKHTVINNSVTLVL 1176
Query 1043 ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGS 1102
D ++ A + V+VNAAN +LKHGGG+AGA+NKA+ +Q ESD+YI+ +GPL VG S
Sbjct 1177 GDAIQIASLLPKCVLVNAANRHLKHGGGIAGAINKASGGDVQEESDEYISNSGPLHVGDS 1236
Query 1103 CVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADP 1158
+L G+ LA L VVGP+ ED LLK Y+ FN+H +++ PL+S+GIF DP
Sbjct 1237 VLLKGYGLADAILRVVGPDARNNEDAALLKRCYKTFNKHTIVVTPLISSGIFSVDP 1292
>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119
Score = 5604 bits (14538), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2741/4914 (56%), Positives = 3537/4914 (72%), Gaps = 83/4914 (2%)
Query 2230 IIWFLLLSVCLGSLIYSTAALGVLM------SNLGMPSYCTGYREGYLNSTNVTIATYCT 2283
I +L + L S + A G+L S LG+ + C G Y N T+ + +C+
Sbjct 2236 IYHLVLFNQVLSSDVMLEDATGILAIYKEVRSYLGIRTLCDGLVVEYRN-TSFDVMEFCS 2294
Query 2284 G-SIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLG 2342
S+ C CL G DSL Y +L+ +Q I+S+ ++ E+FLAY+L+T F VL
Sbjct 2295 NRSVLCQWCLIGQDSLTRYSALQMLQTHITSYVLNIDWIWFALEFFLAYVLYTSSFNVLL 2354
Query 2343 LAAIMQLFFSYFA--VHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
L Q FF+Y + V++ + ++++ + LV P+ +VR+Y F A +++ K Y HV
Sbjct 2355 LVVTAQYFFAYTSAFVNWRAYNYIVSGLFFLVTHIPLHGLVRVYNFLACLWFLRKFYSHV 2414
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
++GC + C++CYKRNR TRVE +TIV G +R+FY+ ANGG +C HNWNCV CDT
Sbjct 2415 INGCKDTACLLCYKRNRLTRVEASTIVCGTKRTFYIAANGGTSYCCKHNWNCVECDTAGV 2474
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G+TFI EVA DL+ +R I PTDQS Y VDSV VK+ + L++++ G YER+ L +
Sbjct 2475 GNTFICTEVANDLTTTLRRLIKPTDQSHYYVDSVVVKDAVVELHYNRDGSSCYERYPLCY 2534
Query 2521 FVNLDNLRAN---NTKGSLP-INVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQAL 2576
F NL+ L+ T +P N +++D + +E+ A+SA VYYSQ++C+P+LL+D L
Sbjct 2535 FTNLEKLKFKEVCKTPTGIPEHNFLIYDTNDRGQENLARSACVYYSQVLCKPMLLVDVNL 2594
Query 2577 VSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISA 2636
V+ VGDS E+A+KM D+++N+F S F+V +KL+ L+ TA + + NVL TF A
Sbjct 2595 VTTVGDSREIAIKMLDSFINSFISLFSVSRDKLEKLINTARDCVRRGDDFQNVLKTFTDA 2654
Query 2637 AR-QGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCS 2695
AR V+SDVET VV+ L+ +H++DI++T + NNY+ Y K +++ DLG ID
Sbjct 2655 ARGHAGVESDVETTMVVDALQYAHKNDIQLTTECYNNYVPGYIKPDSINTLDLGCLIDLK 2714
Query 2696 ARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVT 2755
A +N ++ N A +WN D+M LS+ ++QIR A +K N+PF+LT + R N+++
Sbjct 2715 AASVNQTSMRNANGACVWNSGDYMKLSDSFKRQIRIACRKCNIPFRLTTSKLRAADNILS 2774
Query 2756 TKIALKGGKIVN---NWLKQLIKVTL-------VFLF-VAAIFYLITPVHVMSKHTDFSS 2804
K + KIV +WL ++ +T+ +F+F VA + + P + ++
Sbjct 2775 VKFS--ATKIVGGAPSWLLRVRDLTVKGYCILTLFVFTVAVLSWFCLPSYSIATVNFNDD 2832
Query 2805 EIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQ-RGGSYTNDKACPLIAAVITREVG 2863
I+ YK I+ G+ RDIA D CFANK+ F WF++ GG Y N CP+ AVI G
Sbjct 2833 RILTYKVIENGIVRDIAPNDVCFANKYGHFSKWFNENHGGVYRNSMDCPITIAVIAGVAG 2892
Query 2864 FVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFK 2923
V +P L + F+ RVF A N+C+TP I Y F+ S CVL++ECT+F+
Sbjct 2893 ARVANVPAN-LAWVGKQIVLFVSRVF-ANTNVCFTPINEIPYDTFSDSGCVLSSECTLFR 2950
Query 2924 DASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSI-IQFPNTYLEGSVRVVTTFDSE 2982
DA G P+CYD VL G+ +Y ++P RY + D + I+FP +E ++R+ T ++
Sbjct 2951 DAEGNLNPFCYDPTVLPGASSYADMKPHVRYDMYDSDMYIKFPEVIVESTLRITKTLATQ 3010
Query 2983 YCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALD 3042
YCR G+CE S AGVC+ST+G W L N Y + PG++CG D +++ + L QP+
Sbjct 3011 YCRFGSCEESAAGVCISTNGSWALYNQNYSTRPGIYCGDDYFDIVRRLAISLFQPVTYFQ 3070
Query 3043 ISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLP 3102
+S S+ G ++ + +T YY + +RA +Y+ + L++ LC L
Sbjct 3071 LSTSLAMGLVLCVFLTAAFYYINKVKRALADYTQCAVVAVVAALLNSLCLCFIVANPLLV 3130
Query 3103 GVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLK 3162
Y+ +Y Y TFYLT + +F+ HI W VMF +VP W+ +Y + + +H +W + + K
Sbjct 3131 APYTAMYYYATFYLTGEPAFIMHISWYVMFGAVVPIWMLASYTVGVMLRHLFWVLAYFSK 3190
Query 3163 RRV-VF-NGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQ--YNRYLALYNKYKYFS 3218
+ V VF +G +F++AA F++ K+ Y+ LR+ +TQ + RYL+L+NKYKY+S
Sbjct 3191 KHVDVFTDGKLNCSFQDAASNIFVIGKDTYVALRN----AITQDSFVRYLSLFNKYKYYS 3246
Query 3219 GAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEG 3278
GAMDT SYREA HL KAL +S +GSD+LYQPP S+TS+VLQSG KM+ PSG VE
Sbjct 3247 GAMDTASYREACAAHLCKALQTYSETGSDILYQPPNCSVTSSVLQSGLVKMSAPSGAVEN 3306
Query 3279 CMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQ---AGN 3335
C+VQVTCG+ TLNGLWLD+ V+CPRH++C ++ + +PNY+ LLI K+NH+F+VQ
Sbjct 3307 CIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLISKTNHSFIVQKHIGAQ 3366
Query 3336 VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRP 3395
LRV+ HSM +LKL VD ANP TP Y F ++PG +FSVLACYNG P+GV+ +R
Sbjct 3367 ANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRH 3426
Query 3396 NFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQ 3455
N TIKGSFL GSCGSVG+ + ++F YMH MEL G H G+ +G YG F D+QT Q
Sbjct 3427 NSTIKGSFLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQ 3486
Query 3456 AAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY-EPLTQDHVDILG 3514
TD T+NV+AWLYAAV+NG +WF+ + +N A+ + E + +D+L
Sbjct 3487 LQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVGTQSIDML- 3545
Query 3515 PLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKR 3574
+ +TG++V M A+++ L G G+TILG + LEDEFTP DV Q GV QS VKR
Sbjct 3546 --AHRTGVSVEQMLAAIQSL-HAGFQGKTILGQSTLEDEFTPDDVNMQVMGVVMQSGVKR 3602
Query 3575 TIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHA 3634
G HWL+ T + + + ++Q T+++++ +L+E ++ A M VKHKH
Sbjct 3603 ISYGFIHWLISTFVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLLGFMACVMFTVKHKHT 3662
Query 3635 FLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 3690
F+ LFLLP + Y N+VY P +S ++ + WL + D +Y S
Sbjct 3663 FMSLFLLPVALCLTYANIVYEPQTLISSTLIAVANWLTPTSVYMRTTHF-DFGLYISLSF 3721
Query 3691 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 3750
+L ++ R + L + + Y G+ I+ I ++TS+Y+ V
Sbjct 3722 VLAIIVRRLYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYTITVFA 3780
Query 3751 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 3810
+ LA+ I + Y P ++ ++L+Y LGY CT YFG+F LLN R+ LGV
Sbjct 3781 TVNLAKFISGLVFFYAPHLGFILPEVKLVLLIYLGLGYMCTMYFGVFSLLNLKLRVPLGV 3840
Query 3811 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSV 3870
YDY VSTQEFR++ GL P+NS +A LN KLLG+GG PCIKVATVQSK++D+KCTSV
Sbjct 3841 YDYSVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQSKLTDLKCTSV 3900
Query 3871 VLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKL 3930
VLL+VLQQL +ES+SK W+ CV+LHN+IL A D TEAFE+ V L + L+S VD++ L
Sbjct 3901 VLLTVLQQLHLESNSKAWSYCVKLHNEILAAVDPTEAFERFVCLFATLMSFSANVDLDAL 3960
Query 3931 CEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKS 3989
++ +N + LQA +EFS L +YA TAQ +Y++A+ +GD S VLK L+K++NVAK+
Sbjct 3961 ANDLFENSSVLQATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKN 4020
Query 3990 EFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNII 4049
+++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I
Sbjct 4021 AYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVI 4080
Query 4050 NNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIV 4109
NAR+GCVPL+I+PL + KL VVIPD + + + + +YA +LW+I + + D+++V
Sbjct 4081 ANARNGCVPLSIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVV 4140
Query 4110 QLSEISMDNSPNLAWPLIVTALRANS-AVKLQNNELSPVALRQMSCAAGTTQTACTDDNA 4168
+ +++ ++ + +L WPL++ R++S AVKLQNNE+ P L+ M AG Q C + +A
Sbjct 4141 KPTDV-VETNESLTWPLVIECSRSSSSAVKLQNNEIHPKGLKTMVITAGVDQVNC-NSSA 4198
Query 4169 LAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL 4228
+AYY +G R V+ LLS+ LKWA+ DG I EL+PPC+F+ PKGP+++YL
Sbjct 4199 VAYYEPVQGHRMVMGLLSENAHLKWAKVEGKDGF--INIELQPPCKFLIAGPKGPEIRYL 4256
Query 4229 YFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGG 4288
YF+K LNNL+RG +LG +AATVRLQAG TE +NSTVL+ AFAVD AKAY DY+ SGG
Sbjct 4257 YFVKNLNNLHRGQLLGHIAATVRLQAGANTEFASNSTVLTLVAFAVDPAKAYLDYVGSGG 4316
Query 4289 QPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGK 4348
P++N VKML TGTG AI+V PEA DQE++GGAS CLYCR HI+HP+ G C K +
Sbjct 4317 TPLSNYVKMLAPKTGTGVAISVKPEATADQETYGGASVCLYCRAHIEHPDVSGVCKYKTR 4376
Query 4349 YVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA 4408
+VQIP DPVGF LKN C VC W GYGC+CD LR + + +FLNRV G S
Sbjct 4377 FVQIPAH-VRDPVGFLLKNVPCNVCQYWVGYGCNCDALRNNTVPQSKDTNFLNRVRGSSV 4435
Query 4409 -ARLTPCGTGTSTDVVYRAFDIYNDK--VAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVK 4465
ARL PC +G +TDVVYRAFDI N K VAG K+ KTN CRF + D++ + +DSYF+VK
Sbjct 4436 NARLEPCSSGLTTDVVYRAFDICNFKARVAGIGKYYKTNTCRFVQVDDEGHKLDSYFIVK 4495
Query 4466 RHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRH 4525
RHT SNY+ E+ Y+LLKDC AVA HDFF F +D PHI RQ LT+YTM DLVYALRH
Sbjct 4496 RHTMSNYELEKRCYDLLKDCDAVAIHDFFIFDVDKTKTPHIVRQSLTEYTMMDLVYALRH 4555
Query 4526 FDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFC 4585
FD+ NC+ LK ILV Y CC+ YF+ K W+DFVENP ++ VY LGER+RQA+L TV+ C
Sbjct 4556 FDQNNCEVLKSILVKYGCCEQSYFDNKLWFDFVENPSVIGVYHKLGERIRQAMLNTVKMC 4615
Query 4586 DAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTA 4645
D M +G+VGVLTLDNQDLNG WYDFGDF+ T PG+GV +VDSYYS LMP+L++T L A
Sbjct 4616 DHMVKSGLVGVLTLDNQDLNGKWYDFGDFVITQPGAGVAIVDSYYSYLMPVLSMTNCLAA 4675
Query 4646 ESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANF 4705
E+H D D KP I+W LL+YD+T+ ++ LF++YFKYWDQTYHPNCVNC DDRCILHCANF
Sbjct 4676 ETHKDCDFNKPLIEWPLLEYDYTDYKIGLFNKYFKYWDQTYHPNCVNCSDDRCILHCANF 4735
Query 4706 NVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLV 4765
NVLFS V P TSFGP+VRKIFVDGVPF+VS GYH++ELG+V N D N+H RL+ KEL++
Sbjct 4736 NVLFSMVLPNTSFGPIVRKIFVDGVPFIVSCGYHYKELGLVMNMDFNIHRHRLALKELMM 4795
Query 4766 YAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGS 4825
YAADPAMH AS + L D RT CFSVAALT + FQTV+PGNFNKDFYDF VS+GFFKEGS
Sbjct 4796 YAADPAMHIASASALWDLRTPCFSVAALTTGLTFQTVRPGNFNKDFYDFVVSRGFFKEGS 4855
Query 4826 SVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQV 4885
SV LKHFFFAQDG+AAI+DY YY YNLPTM DI+Q+LF +EVVDKYFD YDGGC+NA++V
Sbjct 4856 SVTLKHFFFAQDGHAAITDYSYYAYNLPTMVDIKQMLFCMEVVDKYFDIYDGGCLNASEV 4915
Query 4886 IVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNR 4945
IVNNLDKSAG PFNK+GKAR+YY+SMSY++QD LFA TKRNV+PTITQMNLKYAISAKNR
Sbjct 4916 IVNNLDKSAGHPFNKFGKARVYYESMSYQEQDELFAVTKRNVLPTITQMNLKYAISAKNR 4975
Query 4946 ARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPH 5005
ARTVAGVSI STMTNRQ+HQK+LKS+AATRGAT VIGT+KFYGGW MLKT+Y DVE+PH
Sbjct 4976 ARTVAGVSILSTMTNRQYHQKMLKSMAATRGATCVIGTTKFYGGWDFMLKTLYKDVESPH 5035
Query 5006 LMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSL 5065
LMGWDYPKCDRAMPNM RI+ASL+LARKH+TCC+ S RFYRLANECAQVLSE V+CGG
Sbjct 5036 LMGWDYPKCDRAMPNMCRILASLILARKHSTCCTNSDRFYRLANECAQVLSEYVLCGGGY 5095
Query 5066 YVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYR 5125
YVKPGGTSSGDATTAYANSVFNI QA TANV+AL+S +GN I D+ ++++Q LY +YR
Sbjct 5096 YVKPGGTSSGDATTAYANSVFNILQATTANVSALMSANGNTIIDREIKDMQFDLYINVYR 5155
Query 5126 NRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVF 5185
D FV+++YA+L KHFSMMILSDD VVC+NS YA++G VASI+NFK LYYQNNVF
Sbjct 5156 KVVPDPKFVDKYYAFLNKHFSMMILSDDGVVCYNSDYAAKGYVASIQNFKETLYYQNNVF 5215
Query 5186 MSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGT 5245
MSEAKCW ET+L KGPHEFCSQHT+ +K GDD +LPYPDPSRIL AGCFVDDIVKTDGT
Sbjct 5216 MSEAKCWVETNLEKGPHEFCSQHTLYIKDGDDGYFLPYPDPSRILSAGCFVDDIVKTDGT 5275
Query 5246 LMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTS 5305
+M+ER+VSLAIDAYPLTKH + EY +VF +YLQYI KL+ +LTGHMLD YSVML D+++
Sbjct 5276 VMMERYVSLAIDAYPLTKHDDTEYQNVFWVYLQYIEKLYKDLTGHMLDSYSVMLCGDDSA 5335
Query 5306 RYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKL 5365
++WE FY +Y+ T LQAVG+CV+C+SQTSLRCG CIRRPFLCCKCCYDHVI+T HK+
Sbjct 5336 KFWEEGFYRDLYSSPTTLQAVGSCVVCHSQTSLRCGTCIRRPFLCCKCCYDHVIATPHKM 5395
Query 5366 VLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSD 5425
VLSV+PYVCNAPGCDV+DVT+LYLGGMSYYC H+P SFPLCANG VFGLYKN C GS
Sbjct 5396 VLSVSPYVCNAPGCDVSDVTKLYLGGMSYYCNDHRPVCSFPLCANGLVFGLYKNMCTGSS 5455
Query 5426 NVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDR 5485
++ +FN +ATCDW+++GDY LANT TE LKLFAAETL+ATEE K SY IAT++E++ +R
Sbjct 5456 SIMEFNRLATCDWSDSGDYTLANTTTEPLKLFAAETLRATEEASKQSYAIATIKEIVGER 5515
Query 5486 ELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNV 5545
EL L WEVGK +PPLNRNYVFTGY +TKNSKVQ+GEY FE+ DY DAV Y+ +TTYKL V
Sbjct 5516 ELILVWEVGKSKPPLNRNYVFTGYHLTKNSKVQLGEYVFERIDYSDAVSYKSSTTYKLAV 5575
Query 5546 GDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQ 5605
GD FVLTSH+V LSAPT+V QE Y++ITG+YPT+ + +EF+++V N+QK G KY T+Q
Sbjct 5576 GDIFVLTSHSVATLSAPTIVNQERYLKITGIYPTITVPEEFANHVVNFQKAGFSKYVTVQ 5635
Query 5606 GPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVE 5665
GPPGTGKSHFAIGLA+YYP+ARIVYTACSHAAVDALCEKA KYL I KCSRIIPA+ARVE
Sbjct 5636 GPPGTGKSHFAIGLAIYYPTARIVYTACSHAAVDALCEKAFKYLNIAKCSRIIPAKARVE 5695
Query 5666 CFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGD 5725
C+D+FKVN T QY+F TVNALPE + DI+V DE+SM TNYDLS++N+R++AKH VY+GD
Sbjct 5696 CYDRFKVNDTNSQYLFSTVNALPEISVDILVVDEVSMCTNYDLSIINSRVKAKHIVYVGD 5755
Query 5726 PAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKL 5785
PAQLPAPRTLL +GTLEPE FNSV RLM +GPD+FL C RCP EIV TVSALVY+NKL
Sbjct 5756 PAQLPAPRTLLIRGTLEPENFNSVTRLMCNLGPDIFLSVCYRCPKEIVSTVSALVYNNKL 5815
Query 5786 KAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAV 5845
A KD S QCFK+ +KG +THD SSAINRPQ+ V+ F+ NP W KAVFISPYNSQNAV
Sbjct 5816 SAKKDASGQCFKILFKGSVTHDASSAINRPQLNFVKTFIAANPNWSKAVFISPYNSQNAV 5875
Query 5846 ASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
A +LGL TQTVDSSQGSEY YVIF QT +TAH+ N+NRFNVA+TRA+ GILC+M+ + L
Sbjct 5876 ARSMLGLTTQTVDSSQGSEYPYVIFCQTADTAHANNLNRFNVAVTRAQKGILCVMTSQVL 5935
Query 5906 YDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLC 5964
+D L+F L + N LQ++ VTGLFKDCS+ TGL P APT+LSVD K+K T+ LC
Sbjct 5936 FDSLEFAELSL---NNYKLQSQIVTGLFKDCSREDTGLPPAYAPTYLSVDAKYKTTDELC 5992
Query 5965 VDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRE 6024
V++ I ++TY R+IS MGFK++ + GYP +FITR+EAIR VR+W+GFDVEG HA+R
Sbjct 5993 VNL-NITPNVTYSRVISRMGFKLDATIPGYPKLFITRDEAIRQVRSWVGFDVEGAHASRN 6051
Query 6025 AVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPW 6084
A GTN+PLQLGFSTGVN V P G VDT + + +SA+PPPG+QFKHL+PLM KG W
Sbjct 6052 ACGTNVPLQLGFSTGVNFVVQPVGVVDTEWGSMLTTISARPPPGEQFKHLVPLMNKGATW 6111
Query 6085 NVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFST 6144
+VR +IVQMLSDTL LSD FV WAHGFELTS YF KIG E+ C +C RRA+ FS+
Sbjct 6112 PIVRRRIVQMLSDTLDKLSDYCTFVCWAHGFELTSASYFCKIGKEQRCSMCSRRASTFSS 6171
Query 6145 ASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRC 6204
+YACW HS G+DYVYNPF +DVQQWG+ GNL +NHD YC +H AHVAS DAIMTRC
Sbjct 6172 PLQSYACWSHSSGYDYVYNPFFVDVQQWGYVGNLATNHDRYCGIHAGAHVASSDAIMTRC 6231
Query 6205 LAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIK 6264
LA+++CF++RVDW + YP I E K+N+ CR V+ VV++A+L+ KF ++DIGNPK I
Sbjct 6232 LAIYDCFIERVDWDVTYPYISHEQKLNSCCRTVERNVVRSAVLSGKFEKIYDIGNPKGIA 6291
Query 6265 CVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVC 6324
+ + VEW FYDAQP S+ K+++LFY+ S +F DG+CLFWNCNV +YP+N++VC
Sbjct 6292 IISEP-VEWHFYDAQPLSN---KVKKLFYTDDV-SKQFEDGLCLFWNCNVSKYPSNAVVC 6346
Query 6325 RFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGK-Q 6383
RFDTRV S NLPGC+GGSLYVNKHAFHTPA+D +AF +LK LPFFYYS +PCE HG
Sbjct 6347 RFDTRVHSEFNLPGCNGGSLYVNKHAFHTPAYDINAFRDLKPLPFFYYSTTPCEVHGSGN 6406
Query 6384 VVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYN 6443
++ DIDYVPLKSA CIT CNLGGAVCR HA EYR Y++AYN++ +AGF LWVYK FD YN
Sbjct 6407 MLEDIDYVPLKSAVCITACNLGGAVCRKHAAEYRDYMEAYNIVSAAGFRLWVYKTFDIYN 6466
Query 6444 LWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPV 6503
LW+TF ++Q LEN+AFNV+ +GHF G GE+PV+++N+ ++TK DV +F+N+T LP
Sbjct 6467 LWSTFVKVQGLENIAFNVIKQGHFTGVDGELPVAVVNDKIFTKNGTDDVCIFKNETALPT 6526
Query 6504 NVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKP 6563
NVAFEL+AKR ++ P++ +L NL VD+ N V+WDY R+ +TIGVC TDI P
Sbjct 6527 NVAFELYAKRAVRSHPDLNLLRNLEVDVCYNFVLWDYDRNNIYGTTTIGVCKYTDIDVNP 6586
Query 6564 TETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IG 6621
+C FD R G ++ F + NGVLI++ +K GPK A NG L I
Sbjct 6587 NLNMC------FDIRDKGSLERFMSMPNGVLISDRKIKNYPCISGPKHAYFNGAILRNID 6640
Query 6622 EAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEG 6681
F YKKV+ +T++T R + +F + ME DFL L D FI++Y LE
Sbjct 6641 AKQPVIFYLYKKVNNEFVSFSDTFYTCGRTVGDFTVLTPMEEDFLVLDSDVFIKKYGLED 6700
Query 6682 YAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSK 6741
YAFEH+VYGDFSH+ LGGLHLLIGL K+ +E +E+ + +TV NYFITD+ T S K
Sbjct 6701 YAFEHVVYGDFSHTTLGGLHLLIGLYKKMREGHILMEEMLKDRATVHNYFITDSNTASYK 6760
Query 6742 CVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQ 6801
VCSVIDL LDDFV IIK DL VVSKVVKV ID T I FMLWC+DG V+TFYP+LQ++
Sbjct 6761 AVCSVIDLRLDDFVTIIKEMDLDVVSKVVKVPIDLTMIEFMLWCRDGKVQTFYPRLQATN 6820
Query 6802 AWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPY 6861
W+PG+ MP+L+K+Q+M LE C L NY S +P G+ MNVAKY QLCQYLNT TLAVP
Sbjct 6821 DWKPGLTMPSLFKVQQMNLEPCLLANYKQSIPMPNGVHMNVAKYMQLCQYLNTCTLAVPA 6880
Query 6862 NMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANK 6921
NMRVIHFGAG +KGVAPGT+VLRQWLP +L+D+DLN+FVSDAD T+ GDC TVH +
Sbjct 6881 NMRVIHFGAGCEKGVAPGTSVLRQWLPLDAVLIDNDLNEFVSDADITIFGDCVTVHVGQQ 6940
Query 6922 WDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKL 6981
DL+ISDMYDP TK V + N +K FF Y+C FI+ LALGGSVAIKITEHSW+ADLYK+
Sbjct 6941 VDLLISDMYDPCTKAVGEVNQTKALFFVYLCNFIKNNLALGGSVAIKITEHSWSADLYKI 7000
Query 6982 MGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYS 7041
MG FA+WT F TN NASSSE FLIG N+LG+ +E+IDG VMHANYIFWRN+ P+ LS+YS
Sbjct 7001 MGRFAYWTVFCTNANASSSEGFLIGINFLGELKEEIDGNVMHANYIFWRNSTPMNLSTYS 7060
Query 7042 LFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
LFD+S+FPLKL+GT V+ LKE QIN++++SLLS+G+L+IR+N+ + +S+DVLVN
Sbjct 7061 LFDLSRFPLKLKGTPVLQLKESQINELVISLLSQGKLLIRDNDTLNVSTDVLVN 7114
Score = 305 bits (781), Expect = 1e-80, Method: Compositional matrix adjust.
Identities = 226/771 (29%), Positives = 368/771 (48%), Gaps = 46/771 (6%)
Query 1391 VCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPL 1450
+C E A V ++ K + VD G +Y Y+++ + +I N + + MP
Sbjct 1345 ICTEYSANVKFLRTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGCS-GICAMPF 1402
Query 1451 GYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGS 1510
GYVTHGL+L ++ Y+R +KVP ++S + + N + + +TPE FI ++ G
Sbjct 1403 GYVTHGLDLAQSGNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGG 1460
Query 1511 YKDWSY-SGQSTQLGI---EFLKRGDKSVYYTSNPTTFHLDGEVITFDNL---KTLLSLR 1563
Y W SG + + L +++ Y N + + F +L + L+ R
Sbjct 1461 YHSWHLVSGDLIVKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFSDLEACRAYLTSR 1520
Query 1564 EVR--TIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVL 1621
+ I+V T+D +N T +++ + T+ +Q G T+ G D++ P G++ +V
Sbjct 1521 AAQQVNIEVLVTIDGVNFRTVILNDTTTFRKQLGATFYKGVDISDAFPTVKMGGESLFVA 1580
Query 1622 PN-DDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
N ++ +V EYY T+D +FL RY S ++WK+ +G+ S+K ++ NCY+ +
Sbjct 1581 DNLSESEKVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATI 1640
Query 1681 LTLQQI-ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHA 1739
+ + + ++KF PALQ+AY R + G+ +F ALI+AY + T D + + L A
Sbjct 1641 MMIDMLHDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKA 1700
Query 1740 NLD-SCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLV 1798
L S K V C CG + G+ A +Y G S E+ + C CG + LV
Sbjct 1701 ELTVSAKMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLV 1760
Query 1799 QQESPFVMMSAPPAQYELKHGTFTCASEYTGNY------QCGHYKHITSKETL-YCIDGA 1851
+ +P++++S E+K T T N GHY HI K+ L Y D
Sbjct 1761 EHSAPWLLVSG---LNEVKVSTSTDPIYRAFNVFQGVETSVGHYVHIRVKDGLFYKYDSG 1817
Query 1852 LLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQP 1911
LTK+S+ K +T V+Y YT V Y LDGV E++P L NYY KD Y+T +P
Sbjct 1818 SLTKTSDMKCKMTSVWYPTVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKP 1877
Query 1912 -IDLVPNQPYPNASFDNFKFV-CDNIKFADDL----NQLTGYK--KPASRELKVTFFPDL 1963
I P P + + N V D +D + N L G+ KP S++L + P+
Sbjct 1878 TIKYSPATILPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNE 1937
Query 1964 NGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSN 2023
+GDV+ ++ +Y P +KKG L KPI+W N + A KPN +R L+ P+ N
Sbjct 1938 DGDVLLSEFSNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDN 1997
Query 2024 SFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTE---VVGDIILKPA 2080
+ VL+ +Q E PV ++V P + ++E K V G+
Sbjct 1998 KYTVLQDNTSQ-----LVEHNVPVVDDV---PITTRKLIEVKCKGLNKPFVKGNFSFVND 2049
Query 2081 NNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLATHGLAAV 2130
N + + + +G T+L A YVD N+ + + N S + L T+ + L V
Sbjct 2050 PNGVTVVDTLGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVESGDLQIV 2100
Score = 250 bits (638), Expect = 4e-64, Method: Compositional matrix adjust.
Identities = 314/1301 (24%), Positives = 531/1301 (41%), Gaps = 186/1301 (14%)
Query 8 FNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEVLSEARQHLKD-GTCGLVEVE-KGV 60
+NEK HV ++P+ D+ L F D E ++ LK+ G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTDDMACKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGR-----SGETLGVLVPHVGEIP 115
+ L P V++ H +V +A + + + + LG+ P+ +
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDQVGAAMMRTTLNAKPLGMFFPYDSSLE 139
Query 116 VAYRKVLLRKNGNKGAGGHSYGADLKS---FDLGDELGTDPYEDFQENWNTKHSSGVTRE 172
LLRKNG G D K ++ D+L DP + +N
Sbjct 140 TGEYTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSE-QLDF---IDTKRGV 228
L+++L GG +D CG +G P+ ++A+ G TL++ ++D +D+ R +
Sbjct 188 LLKKLIGGDCIP-IDQYMCGKNGKPIADYAKIVAKEGLT--TLADIEVDVKSRMDSDRFI 244
Query 229 YCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRV 288
+ + + W R Y QT F I + D P F + S I + P +
Sbjct 245 -VLNKKLYRVVWNVTRRNVPYPKQTAFTIVSVVQCDD-KDSVPEHTFTIGSQILMVSP-L 301
Query 289 EKKKLDGFMGRIRSVYPVASPNECNQ---MCLSTLMKCDHCGETSWQTGDFVKATCEFCG 345
+ F + R +Y + Q + S + C+ CG +W TG+ ++ CG
Sbjct 302 KATNNKNFNLKQRLLYTFYGKDAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCG 361
Query 346 TENLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGR-- 402
+ + G +P+NA+ CP +N HS A+ +N K + GG+
Sbjct 362 ANYSANDVDLQSSGLVPRNALFLANCPCANNGAC--SHSAAQVYNILDGKACVEVGGKSF 419
Query 403 TIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEK 458
T+ FGG V++Y+GC + Y+VPRA + + + G G D ++E L+K +
Sbjct 420 TLTFGGVVYAYMGCCDGTMYFVPRAKSCVS-RIGDAIFTGCTGTWDKVVETANLFLEKAQ 478
Query 459 VNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN--FKVTKGKA 516
++N F L E ++LA S +TS F E +++++ + N F VT G
Sbjct 479 RSLNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDY 535
Query 517 KKGAWNIGEQ----KSILSPLYAFAS--EAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
+ A NIG +I +P AF E+ + V +I + N L + I+
Sbjct 536 IRDAINIGANGVCNATINAPFIAFTGLGESFKKVSAI---PWKICSNLKSALDYYSSNIM 592
Query 571 DGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEK----LKP 626
+ Y + D F L + +A + V++ + + GTV L
Sbjct 593 FRVFPYDIP-CDVSNFVELLLDCGKLTVA-TSYFVLRYLDEKFDTVLGTVSSACQTALSS 650
Query 627 VLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFL 686
L+ + F+ D +++ K + V A+ + VQ +++K +
Sbjct 651 FLNACVAASRATAGFINDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLDIMSKAM 710
Query 687 ALCADSIIIGGAKLKALNL-GETFVTHSKGLYRKCVKSREET-----GLLMPLKAPKEII 740
L ++ G KL A+ G + + G Y C+ ++ +T L++P K+ +
Sbjct 711 KLLHTNVSWAGTKLSAIIYEGREALLFNSGTYF-CLSTKAKTLQGQMNLVLPGDYNKKTL 769
Query 741 FL-----EGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKD 795
+ +T+ + V + G L+P T+E + +VG V ++ + + +D
Sbjct 770 GILDPVPNADTIDVNANSTVVDVVHGQLEP----TNEHGPSMIVGNYVLVSDKLFVRTED 825
Query 796 TEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSVNITFELDERIDKVL- 853
E Y L N V + F LKGG P+K VTFGD +EV Y+SV+IT+++ +D +L
Sbjct 826 EEFY-PLCTNGKVVSTLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPVLDALLS 884
Query 854 NEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGE 913
+ K + +TVE V +F V+ D V+ L P+ G D++++ Y++++ G+
Sbjct 885 SSKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYVYNQDGD 944
Query 914 FKLASHMYCSFYP--------------------PDEDEEEGDCEE-EEFEPSTQYEYGTE 952
+S+M S P P D+EE EE P
Sbjct 945 CAWSSNMTFSINPVEDVEEVEEFIEDDYLSDELPIADDEEAWARAVEEVMPLDDILVAEI 1004
Query 953 DDYQGKPLEFGATSA---ALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQ 1009
+ + PLE S ++ E QE DS + G D + + E
Sbjct 1005 ELEEDPPLETALESVEAEVVETAEAQEPSVESIDSTPSTSTVVGENDLSVKPMSRVAETD 1064
Query 1010 PQLEME----------LTPVV----------QTIEVNSFSGYLKLTDNVYIKNAD----- 1044
LE+E +T +V Q V+S + ++N + +D
Sbjct 1065 DVLELETAVVGGPVSDVTAIVTNDIVSVEQAQQCGVSSLPIQDEASENQVHQVSDLQGNE 1124
Query 1045 ---------IVEEAKKVKP---------------TVVVNAANVYLKHGGGVAGALNK--- 1077
IV+ + +KP TV+ N+ + L +A L K
Sbjct 1125 LLCSETKVEIVQPRQDLKPRRSRKSKVDLSKYKHTVINNSVTLVLGDAIQIASLLPKCIL 1184
Query 1078 --------------------ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHV 1117
A+ +Q ESD+YI+ NGPL VG S +L GH LA LHV
Sbjct 1185 VNAANRHLKHGGGIAGVINKASGGDVQEESDEYISNNGPLHVGDSVLLKGHGLADAILHV 1244
Query 1118 VGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADP 1158
VGP+ ED LLK Y+ FN+H +++ PL+SAGIF DP
Sbjct 1245 VGPDARNNEDAALLKRCYKAFNKHTIVVTPLISAGIFSVDP 1285
>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094
Score = 5427 bits (14077), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2760/5619 (49%), Positives = 3706/5619 (66%), Gaps = 182/5619 (3%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E +P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYNPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + I D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTI--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVD 2101
D K E+ I L K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAK-------ESKEINIIKLSGVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLT 2080
Query 2102 NSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNIV 2157
++ N LS + + T+ G+ V S+P D + KP N VV N +
Sbjct 2081 GCRYVVRTANALSMAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNKI 2138
Query 2158 TRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNY 2217
+ C N ++ + F LL + K T +A + + +F
Sbjct 2139 SACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFLT 2189
Query 2218 LKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTN 2275
K ++ II I+ L + ++I+S + +G G ++ ST
Sbjct 2190 FKWSVVARGACIIATIFLLWFNFIYANVIFS----DFYLPKIGFLPTFVGKIAQWIKSTF 2245
Query 2276 --VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAF 2321
VTI YC GSI C CL+G D LD Y +++ +Q ++ D AF
Sbjct 2246 SLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRAF 2300
Query 2322 -------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLV 2372
+V E ++Y L+T +FY L +Q+ ++ F+ ++ W + L+++L
Sbjct 2301 VDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLA 2360
Query 2373 QMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRR 2432
M P +R YI ASF ++ + HV GC+ C+ CYKRNR+ RV+C+TIV G+ R
Sbjct 2361 NMLPAHVFMRFYIIIASFIKLFILFRHVAYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIR 2420
Query 2433 SFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVD 2492
+ V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2421 YYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVT 2480
Query 2493 SVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES 2552
V + L++++ GQ+TY+ + S FV+ NL + KG ++V+V + + +++
Sbjct 2481 DVKQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVENDA--DKA 2538
Query 2553 SAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTL 2612
+ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L L
Sbjct 2539 NFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNAL 2598
Query 2613 VATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCN 2671
+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SCN
Sbjct 2599 IATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCN 2658
Query 2672 NYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRS 2731
N + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2659 NLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKK 2718
Query 2732 AAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLIT 2791
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2719 ACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFLLSLV-CFIG--LWCLM 2775
Query 2792 PVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTND 2848
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2776 PTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSNS 2834
Query 2849 KACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDF 2908
ACP++ AV+ +++G V +P +LR LHF+ SA G CYTP I Y++F
Sbjct 2835 MACPIVVAVVDQDLGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSNF 2893
Query 2909 ATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPNT 2967
S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2894 YASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGFIRFPEV 2953
Query 2968 YLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLL 3027
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L+
Sbjct 2954 LREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDLI 3013
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
+F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ +V N +++ +
Sbjct 3014 YQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWCV 3073
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIIC 3147
+F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3074 NFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYISV 3133
Query 3148 ISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRY 3207
+ + H +W F+ RR+ + S TFEE AL TF++ K+ Y KL++ L +NRY
Sbjct 3134 VVSNHAFWVFA--YCRRLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNRY 3189
Query 3208 LALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSGF 3266
L+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3190 LSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSGI 3249
Query 3267 RKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSN 3326
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R ++
Sbjct 3250 VKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVTS 3309
Query 3327 HNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPS 3386
+F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3310 SDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKPQ 3369
Query 3387 GVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYG 3446
G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+FYG
Sbjct 3370 GAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGDFYG 3429
Query 3447 PFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLT 3506
P+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3430 PYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQVK 3489
Query 3507 QDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGV 3566
D V + L++ TG+++ + A++K L +NG GR I+GS EDE TP DV +Q +G+
Sbjct 3490 SDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVYQQLAGI 3546
Query 3567 TFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAM 3626
QS R +KG W++ + ++ +W++F ++ N L + + + AM
Sbjct 3547 KLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAM 3605
Query 3627 MFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMY 3685
+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3606 LLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIY 3664
Query 3686 ASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNY 3744
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y
Sbjct 3665 GMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTY 3722
Query 3745 SGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYF 3804
+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N F
Sbjct 3723 TWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLF 3781
Query 3805 RLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSD 3864
R+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++D
Sbjct 3782 RMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLTD 3841
Query 3865 VKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGA 3924
VKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL + A
Sbjct 3842 VKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPAA 3901
Query 3925 VD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVL 3977
VD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + + L
Sbjct 3902 VDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQL 3961
Query 3978 KKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTML 4037
K+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+
Sbjct 3962 KQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMV 4021
Query 4038 RKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWE 4097
RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W+
Sbjct 4022 RKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQ 4081
Query 4098 IQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCA 4155
IQ + D+D QL+EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4082 IQTIQDSDGTNKQLNEISDDCN----WPLVIIANRHNEVSATVLQNNELMPAKLKTQVVN 4137
Query 4156 AGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRF 4215
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4138 SGPDQTCNTPTQC--YYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCKF 4194
Query 4216 VTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVD 4275
KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+VD
Sbjct 4195 TVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSVD 4254
Query 4276 AAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHID 4335
K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+YCR ++
Sbjct 4255 PKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIYCRARVE 4314
Query 4336 HPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSAD 4395
HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS D
Sbjct 4315 HPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSKD 4372
Query 4396 AQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDED 4454
+FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRFQ DE+
Sbjct 4373 T-NFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRFQRVDEN 4431
Query 4455 DNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKY 4514
+ +D +FVVKR + Y E Y +KDC VA+HDFF F ++G VPHI R+ LTKY
Sbjct 4432 GDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKDLTKY 4491
Query 4515 TMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERV 4574
TM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY LG
Sbjct 4492 TMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKLGPIF 4551
Query 4575 RQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLM 4634
+AL+ +F D + G+VG+LTLDNQDLNG WYDFGD++ PG GV + DSYYS +M
Sbjct 4552 NRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYYSYMM 4611
Query 4635 PILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCL 4694
P+LT+ AL E +V+ Y +DL++YDFT+ +L+LF++YFK+W YHPN V+C
Sbjct 4612 PMLTMCHALDCELYVNN----AYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNTVDCQ 4667
Query 4695 DDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLH 4754
DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N DV+ H
Sbjct 4668 DDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMDVDTH 4727
Query 4755 SSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDF 4814
RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+DFYDF
Sbjct 4728 RYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYDF 4787
Query 4815 AVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDC 4874
+SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+
Sbjct 4788 ILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEI 4847
Query 4875 YDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQM 4934
YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQM
Sbjct 4848 YDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQM 4907
Query 4935 NLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNML 4994
NLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML
Sbjct 4908 NLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDML 4967
Query 4995 KTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQV 5054
+ + DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS S RFYRLANECAQV
Sbjct 4968 RRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLANECAQV 5027
Query 5055 LSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRN 5114
LSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D +R
Sbjct 5028 LSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDLSIRA 5087
Query 5115 LQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNF 5174
LQ RLY +YR+ VD+ FV E+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I F
Sbjct 5088 LQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIANISAF 5147
Query 5175 KSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGC 5234
+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYPDPSRILGAGC
Sbjct 5148 QQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPDPSRILGAGC 5207
Query 5235 FVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDM 5294
FVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD
Sbjct 5208 FVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNDLGNQILDS 5267
Query 5295 YSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCC 5354
YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCC
Sbjct 5268 YSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCC 5327
Query 5355 YDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVF 5414
YDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L NG VF
Sbjct 5328 YDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVF 5387
Query 5415 GLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYG 5474
GLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK SY
Sbjct 5388 GLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFKQSYA 5447
Query 5475 IATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVV 5534
AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K + + V
Sbjct 5448 SATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELTNGVY 5507
Query 5535 YRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVAN 5592
YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F +NV N
Sbjct 5508 YRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQNNVVN 5564
Query 5593 YQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID 5652
YQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+
Sbjct 5565 YQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLNIN 5624
Query 5653 KCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVN 5712
C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+N
Sbjct 5625 DCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYELSVIN 5684
Query 5713 ARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEI 5772
AR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RCP EI
Sbjct 5685 ARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRCPKEI 5744
Query 5773 VDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRK 5832
VDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL NP W K
Sbjct 5745 VDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANPLWHK 5804
Query 5833 AVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRA 5892
AVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRA
Sbjct 5805 AVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITRA 5864
Query 5893 KVGILCIMSDRDLYDKLQFTSLEIPRRNVAT-LQAENVTGLFKDCSKVITGLHPTQAPTH 5951
K GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP AP+
Sbjct 5865 KKGILCVMSNMQLFEALQFTTLTLDKVPQAVETRVQCSTNLFKDCSKSYSGYHPAHAPSF 5924
Query 5952 LSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRA 6010
L+VD K+K G GI +TY RLIS+MGFK++ ++GY +FIT+EEA++ VRA
Sbjct 5925 LAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEAVKRVRA 5984
Query 6011 WIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQ 6070
W+GFD EG HATR+++GTN PLQLGFSTG++ V TG + F + AK PPG+Q
Sbjct 5985 WVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAKAPPGEQ 6044
Query 6071 FKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPER 6130
FKHLIPLM +G W+VVR +IVQM +D L +LSD VV V WA FELT ++YF K+G E
Sbjct 6045 FKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFAKVGREI 6104
Query 6131 TCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHG 6190
+C +C +RAT +++ + Y CW HS+ DY+YNP ++D+QQWG+ G+L SNHDLYC VH
Sbjct 6105 SCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDLYCSVHK 6164
Query 6191 NAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADK 6250
AHVAS DAIMTRCLAV++CF ++W +EYPII +EL IN +CR +Q +++KAA+L ++
Sbjct 6165 GAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKAAMLCNR 6224
Query 6251 FPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFW 6310
+ + +DIGNPKAI CV D ++KFYDAQP ++ L YS+ H D F DG+C+FW
Sbjct 6225 YTLCYDIGNPKAIACVK--DFDFKFYDAQPI---VKSVKTLLYSFEAHKDSFKDGLCMFW 6279
Query 6311 NCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFF 6370
NCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +LK +PFF
Sbjct 6280 NCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHLKPMPFF 6339
Query 6371 YYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAG 6430
YYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR YL++YN +AG
Sbjct 6340 YYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYNTATTAG 6399
Query 6431 FSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGV 6490
F+ WVYK FD YNLWNTFT+LQSLENV +N+V GH+ GQ GE+P +IIN+ V K+D
Sbjct 6400 FTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKE 6459
Query 6491 DVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHIST 6550
DV +F N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY R++ +T
Sbjct 6460 DVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNT 6519
Query 6551 IGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPK 6610
GVC TD+ L V FDGR +G ++ F+ + NGV I+ VK L GP
Sbjct 6520 YGVCMYTDLK------FIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPP 6573
Query 6611 QASLNGVTL--IGE-------AVKTQ-----FNYYKKVDGVVQQLPE------------- 6643
+A LNGV + +G+ AV+ + F+ + + Q P+
Sbjct 6574 RAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVGG 6633
Query 6644 -------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQ 6696
T FTQSR + F R+ ME DF+ L D FI++Y LE YAFEHIVYG+F+
Sbjct 6634 NDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDLFIQKYGLEDYAFEHIVYGNFNQKI 6693
Query 6697 LGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVE 6756
+GGLHLLIGL +R + S +++F+ DS++ +YFITD ++G SK VC+VID+LLDDFV
Sbjct 6694 IGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVA 6753
Query 6757 IIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQ 6816
++KS +L+ VSKVV V +D+ + FMLWC D V TFYP+LQ++ W+PG +MP LYK
Sbjct 6754 LVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSMPVLYKYL 6813
Query 6817 RMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGV 6876
+E+ L NYG TLP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGS+KGV
Sbjct 6814 NSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSEKGV 6873
Query 6877 APGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKN 6936
APG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDMYDP TKN
Sbjct 6874 APGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMYDPITKN 6933
Query 6937 VTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVN 6996
+ + N SK+GFFTYIC I+ KLALGGSVAIKITE SWNA+LYKLMG+FA+WT F TN N
Sbjct 6934 IGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTVFCTNAN 6993
Query 6997 ASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTA 7056
ASSSE FLIG NYLGKP+ +IDG VMHANY+FWRN+ +YSLFDM+KFPLKL GTA
Sbjct 6994 ASSSEGFLIGINYLGKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFPLKLAGTA 7053
Query 7057 VMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
V++L+ QINDM+ SLL KG+L++R+ N+ V D LVN
Sbjct 7054 VINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDSLVN 7092
Score = 83.2 bits (204), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 79/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFD 1425
Score = 77.0 bits (188), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 207/933 (22%), Positives = 355/933 (38%), Gaps = 164/933 (18%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E S+ L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSLDSLS-AAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F+++ I ++ S V +
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKN---IPRYASA-----VAQAFRS 709
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK + +S++ F + I + G+K+ + G + HS L +
Sbjct 710 VAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP KA ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A +VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRRVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDE 931
+ + +LFDE+GE LAS +YC+F P++D+
Sbjct 936 KLEDNSLFLFDEAGEEVLASKLYCAFTAPEDDD 968
>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094
Score = 5423 bits (14068), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2760/5619 (49%), Positives = 3705/5619 (66%), Gaps = 182/5619 (3%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + +G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGENFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + I D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTI--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVD 2101
D K E+ I L K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAK-------ESKEINIIKLSGVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLT 2080
Query 2102 NSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNIV 2157
++ N+LS + + T+ G+ V S+P D + KP N VV N +
Sbjct 2081 GCRYVVRTANDLSMAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNKI 2138
Query 2158 TRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNY 2217
+ C N ++ + F LL + K T +A + + +F
Sbjct 2139 SACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFLT 2189
Query 2218 LKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTN 2275
K ++ II I+ L + ++I+S + +G G ++ ST
Sbjct 2190 FKWSVVARGACIIATIFLLWFNFIYANVIFS----DFYLPKIGFLPTFVGKIAQWIKSTF 2245
Query 2276 --VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAF 2321
VTI YC GSI C CL+G D LD Y +++ +Q ++ D AF
Sbjct 2246 SLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRAF 2300
Query 2322 -------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLV 2372
+V E ++Y L+T +FY L +Q+ ++ F+ ++ W + L+++L
Sbjct 2301 VDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLA 2360
Query 2373 QMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRR 2432
M P +R YI ASF ++ + HV GC+ C+ CYKRNR+ RV+C+TIV G+ R
Sbjct 2361 NMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIR 2420
Query 2433 SFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVD 2492
+ V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2421 YYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVT 2480
Query 2493 SVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES 2552
V + L++++ GQ+TY+ + S FV+ NL + KG ++V+V + + +++
Sbjct 2481 DVKQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVENDA--DKA 2538
Query 2553 SAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTL 2612
+ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L L
Sbjct 2539 NFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNAL 2598
Query 2613 VATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCN 2671
+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SCN
Sbjct 2599 IATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCN 2658
Query 2672 NYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRS 2731
N + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2659 NLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKK 2718
Query 2732 AAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLIT 2791
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2719 ACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFLLSLV-CFIG--LWCLM 2775
Query 2792 PVHVMSKHTDFSSEI-IGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTND 2848
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2776 PTYTVHK-SDFQLPVYTSYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSNS 2834
Query 2849 KACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDF 2908
ACP++ AV+ +++G V +P +LR LHF+ SA G CYTP I Y++F
Sbjct 2835 MACPIVVAVVDQDLGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSNF 2893
Query 2909 ATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPNT 2967
S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2894 YASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGFIRFPEV 2953
Query 2968 YLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLL 3027
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L+
Sbjct 2954 LREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDLI 3013
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
+F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ +V N +++ +
Sbjct 3014 YQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWCV 3073
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIIC 3147
+F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3074 NFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYISV 3133
Query 3148 ISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRY 3207
+ + H +W F+ RR+ + S TFEE AL TF++ K+ Y KL++ L +NRY
Sbjct 3134 VVSNHAFWVFA--YCRRLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNRY 3189
Query 3208 LALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSGF 3266
L+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3190 LSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSGI 3249
Query 3267 RKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSN 3326
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R ++
Sbjct 3250 VKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVTS 3309
Query 3327 HNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPS 3386
+F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3310 SDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKPQ 3369
Query 3387 GVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYG 3446
G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+FYG
Sbjct 3370 GAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGDFYG 3429
Query 3447 PFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLT 3506
P+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3430 PYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQVK 3489
Query 3507 QDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGV 3566
D V + L++ TG+++ + A++K L +NG GR I+GS EDE TP DV +Q +G+
Sbjct 3490 SDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVYQQLAGI 3546
Query 3567 TFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAM 3626
QS R +KG W++ + ++ +W++F ++ N L + + + AM
Sbjct 3547 KLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAM 3605
Query 3627 MFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMY 3685
+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3606 LLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIY 3664
Query 3686 ASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNY 3744
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y
Sbjct 3665 GMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTY 3722
Query 3745 SGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYF 3804
+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N F
Sbjct 3723 TWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLF 3781
Query 3805 RLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSD 3864
R+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++D
Sbjct 3782 RMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLTD 3841
Query 3865 VKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGA 3924
VKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL + A
Sbjct 3842 VKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPAA 3901
Query 3925 VD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVL 3977
VD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + + L
Sbjct 3902 VDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQL 3961
Query 3978 KKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTML 4037
K+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+
Sbjct 3962 KQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMV 4021
Query 4038 RKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWE 4097
RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W+
Sbjct 4022 RKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQ 4081
Query 4098 IQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCA 4155
IQ + D+D QL+EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4082 IQTIQDSDGTNKQLNEISDDCN----WPLVIIANRHNEVSATVLQNNELMPAKLKTQVVN 4137
Query 4156 AGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRF 4215
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4138 SGPDQTCNTPTQC--YYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCKF 4194
Query 4216 VTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVD 4275
KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+VD
Sbjct 4195 TVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSVD 4254
Query 4276 AAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHID 4335
K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+YCR ++
Sbjct 4255 PKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIYCRARVE 4314
Query 4336 HPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSAD 4395
HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS D
Sbjct 4315 HPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSKD 4372
Query 4396 AQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDED 4454
+FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRFQ DE+
Sbjct 4373 T-NFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRFQRVDEN 4431
Query 4455 DNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKY 4514
+ +D +FVVKR + Y E Y +KDC VA+HDFF F ++G VPHI R+ LTKY
Sbjct 4432 GDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKDLTKY 4491
Query 4515 TMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERV 4574
TM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY LG
Sbjct 4492 TMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKLGPIF 4551
Query 4575 RQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLM 4634
+AL+ +F D + G+VG+LTLDNQDLNG WYDFGD++ PG GV + DSYYS +M
Sbjct 4552 NRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYYSYMM 4611
Query 4635 PILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCL 4694
P+LT+ AL E +V+ Y +DL++YDFT+ +L+LF++YFK+W YHPN V+C
Sbjct 4612 PMLTMCHALDCELYVNN----AYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNTVDCQ 4667
Query 4695 DDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLH 4754
DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N DV+ H
Sbjct 4668 DDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMDVDTH 4727
Query 4755 SSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDF 4814
RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+DFYDF
Sbjct 4728 RYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYDF 4787
Query 4815 AVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDC 4874
+SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+
Sbjct 4788 ILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEI 4847
Query 4875 YDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQM 4934
YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQM
Sbjct 4848 YDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQM 4907
Query 4935 NLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNML 4994
NLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML
Sbjct 4908 NLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDML 4967
Query 4995 KTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQV 5054
+ + DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS S RFYRLANECAQV
Sbjct 4968 RRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLANECAQV 5027
Query 5055 LSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRN 5114
LSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D +R
Sbjct 5028 LSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDLSIRA 5087
Query 5115 LQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNF 5174
LQ RLY +YR+ VD+ FV E+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I F
Sbjct 5088 LQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIANISAF 5147
Query 5175 KSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGC 5234
+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYPDPSRILGAGC
Sbjct 5148 QQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPDPSRILGAGC 5207
Query 5235 FVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDM 5294
FVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD
Sbjct 5208 FVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNDLGNQILDS 5267
Query 5295 YSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCC 5354
YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCC
Sbjct 5268 YSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCC 5327
Query 5355 YDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVF 5414
YDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L NG VF
Sbjct 5328 YDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVF 5387
Query 5415 GLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYG 5474
GLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK SY
Sbjct 5388 GLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFKQSYA 5447
Query 5475 IATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVV 5534
AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K + + V
Sbjct 5448 SATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELTNGVY 5507
Query 5535 YRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVAN 5592
YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F +NV N
Sbjct 5508 YRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQNNVVN 5564
Query 5593 YQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID 5652
YQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+
Sbjct 5565 YQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLNIN 5624
Query 5653 KCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVN 5712
C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+N
Sbjct 5625 DCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYELSVIN 5684
Query 5713 ARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEI 5772
AR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RCP EI
Sbjct 5685 ARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRCPKEI 5744
Query 5773 VDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRK 5832
VDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL NP W K
Sbjct 5745 VDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANPLWHK 5804
Query 5833 AVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRA 5892
AVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRA
Sbjct 5805 AVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITRA 5864
Query 5893 KVGILCIMSDRDLYDKLQFTSLEIPRRNVAT-LQAENVTGLFKDCSKVITGLHPTQAPTH 5951
K GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP AP+
Sbjct 5865 KKGILCVMSNMQLFEALQFTTLTLDKVPQAVETRVQCSTNLFKDCSKSYSGYHPAHAPSF 5924
Query 5952 LSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRA 6010
L+VD K+K G GI +TY RLIS+MGFK++ ++GY +FIT+EEA++ VRA
Sbjct 5925 LAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEAVKRVRA 5984
Query 6011 WIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQ 6070
W+GFD EG HATR+++GTN PLQLGFSTG++ V TG + F + AK PPG+Q
Sbjct 5985 WVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAKAPPGEQ 6044
Query 6071 FKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPER 6130
FKHLIPLM +G W+VVR +IVQM +D L +LSD VV V WA FELT ++YF K+G E
Sbjct 6045 FKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFAKVGREI 6104
Query 6131 TCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHG 6190
+C +C +RAT +++ + Y CW HS+ DY+YNP ++D+QQWG+ G+L SNHDLYC VH
Sbjct 6105 SCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDLYCSVHK 6164
Query 6191 NAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADK 6250
AHVAS DAIMTRCLAV++CF ++W +EYPII +EL IN +CR +Q +++KAA+L ++
Sbjct 6165 GAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKAAMLCNR 6224
Query 6251 FPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFW 6310
+ + +DIGNPKAI CV D ++KFYDAQP ++ L YS+ H D F DG+C+FW
Sbjct 6225 YTLCYDIGNPKAIACVK--DFDFKFYDAQPI---VKSVKTLLYSFEAHKDSFKDGLCMFW 6279
Query 6311 NCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFF 6370
NCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +LK +PFF
Sbjct 6280 NCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHLKPMPFF 6339
Query 6371 YYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAG 6430
YYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR YL++YN +AG
Sbjct 6340 YYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYNTATTAG 6399
Query 6431 FSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGV 6490
F+ WVYK FD YNLWNTFT+LQSLENV +N+V GH+ GQ GE+P +IIN+ V K+D
Sbjct 6400 FTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKE 6459
Query 6491 DVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHIST 6550
DV +F N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY R++ +T
Sbjct 6460 DVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNT 6519
Query 6551 IGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPK 6610
GVC TD+ L V FDGR +G ++ F+ + NGV I+ VK L GP
Sbjct 6520 YGVCMYTDLK------FIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPP 6573
Query 6611 QASLNGVTL--IGE-------AVKTQ-----FNYYKKVDGVVQQLPE------------- 6643
+A LNGV + +G+ AV+ + F+ + + Q P+
Sbjct 6574 RAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVGG 6633
Query 6644 -------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQ 6696
T FTQSR + F R+ ME DF+ L D FI++Y LE YAFEHIVYG+F+
Sbjct 6634 NDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDLFIQKYGLEDYAFEHIVYGNFNQKI 6693
Query 6697 LGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVE 6756
+GGLHLLIGL +R + S +++F+ DS++ +YFITD ++G SK VC+VID+LLDDFV
Sbjct 6694 IGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVA 6753
Query 6757 IIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQ 6816
++KS +L+ VSKVV V +D+ + FMLWC D V TFYP+LQ++ W+PG +MP LYK
Sbjct 6754 LVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSMPVLYKYL 6813
Query 6817 RMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGV 6876
+E+ L NYG TLP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGS+KGV
Sbjct 6814 NSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSEKGV 6873
Query 6877 APGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKN 6936
APG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDMYDP TKN
Sbjct 6874 APGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMYDPITKN 6933
Query 6937 VTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVN 6996
+ + N SK+GFFTYIC I+ KLALGGSVAIKITE SWNA+LYKLMG+FA+WT F TN N
Sbjct 6934 IGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTVFCTNAN 6993
Query 6997 ASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTA 7056
ASSSE FLIG NYLGKP+ +IDG VMHANY+FWRN+ +YSLFDM+KFPLKL GTA
Sbjct 6994 ASSSEGFLIGINYLGKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFPLKLAGTA 7053
Query 7057 VMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
V++L+ QINDM+ SLL KG+L++R+ N+ V D LVN
Sbjct 7054 VINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDSLVN 7092
Score = 83.2 bits (204), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 79/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFD 1425
Score = 77.0 bits (188), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 207/933 (22%), Positives = 355/933 (38%), Gaps = 164/933 (18%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E S+ L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSLDSLS-AAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F+++ I ++ S V +
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKN---IPRYASA-----VAQAFRS 709
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK + +S++ F + I + G+K+ + G + HS L +
Sbjct 710 VAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP KA ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A +VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRRVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVVDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDE 931
+ + +LFDE+GE LAS +YC+F P++D+
Sbjct 936 KLEDNSLFLFDEAGEEVLASKLYCAFTAPEDDD 968
>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095
Score = 5406 bits (14024), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2764/5626 (49%), Positives = 3699/5626 (66%), Gaps = 195/5626 (3%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCFKWQVVVNGKYFTFKQANNNCFVNVSCLMLQSLH 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
L F Q+A+ R+G A F AL+LA G+ D R+ + +F +L
Sbjct 1685 LTFKIVQWQEAWLEFRSGRPARFVALVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q G++AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGLDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFIGD-NVGHYVHVKCEQSYQLYDASNVKKVTDVTGKLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + + D LN G+ E K+T +P GDVV + Y +++G
Sbjct 1920 YTNFKLIGHTV--CDSLNSKLGFDSSKEFVEYKITEWPTATGDVVLANDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D + +
Sbjct 1978 ITFGKPVIWLSHEKASLNSLTY----------FNRPLLVDDNKFDVLKVDDVDDSGDSSE 2027
Query 2042 EDLKPVSE-EVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
K E +++ ++K +V +I+ + K + + D+ ++
Sbjct 2028 SGAKETKEINIIKLSGVKKPF--------KVEDSVIVNDDTSETKYVKSLSIVDVYDMWL 2079
Query 2101 DNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNI 2156
++ N LSR + + T+ G+ V S+P D + KP +N VV N
Sbjct 2080 TGCKYVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPAVN-VVKAVRNK 2137
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
+ C N ++ + F LL + K T IA + + +F
Sbjct 2138 TSACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEIASKLTCKLVALAFKNAFL 2188
Query 2217 YLKSPNFSKLINII--IWFLLLSVCLGSLIYSTAAL---GVLMSNLG-----------MP 2260
K ++ II I+ L + ++I+S L G L + +G +
Sbjct 2189 TFKWSMVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIAQWIKNTFSLV 2248
Query 2261 SYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTA 2320
+ C Y + N YC GSI C CL+G D LD Y +++ +Q ++ D A
Sbjct 2249 TICDLYSIQDVGFKN----QYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRA 2299
Query 2321 F-------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINL 2371
F +V E ++Y L+T +FY L +Q+ ++ F+ ++ W L++ L
Sbjct 2300 FVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSFRLLVAL 2359
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
M P +R YI ASF ++ + HV GC+ S C+ CYKRNR+ RV+C+TIV G+
Sbjct 2360 ANMLPAHVFMRFYIIIASFIKLFSLFKHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMI 2419
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2420 RYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTV 2479
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEE 2551
V S+ L++D+ GQ+ Y+ + S FV+ NL + K ++V+V + + ++
Sbjct 2480 TDVKQVGCSMRLFYDRDGQRIYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DK 2537
Query 2552 SSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKT 2611
++ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L
Sbjct 2538 ANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNA 2597
Query 2612 LVATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSC 2670
L+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SC
Sbjct 2598 LIATAHSSIKQGTQIYKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESC 2657
Query 2671 NNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIR 2730
NN + TY K +N+ DLG I SA+H+ VAK ++ IW+V F S + +++
Sbjct 2658 NNLVPTYLKSDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQFSSDFQHKLK 2717
Query 2731 SAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLI 2790
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2718 KACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLV-CFIG--LWCL 2774
Query 2791 TPVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTN 2847
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2775 MPTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2848 DKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTD 2907
ACP++ AVI ++ G V +P +LR LHF+ SA G CYTP I Y++
Sbjct 2834 SMACPIVVAVIDQDFGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2908 FATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPN 2966
F S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2893 FYASGCVLSSACTMFTMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRFPE 2952
Query 2967 TYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNL 3026
EG VRVV T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L
Sbjct 2953 VLREGLVRVVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3027 LTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL 3086
+ +F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ VV N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSVVFVNVIVWC 3072
Query 3087 MSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYII 3146
++F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIA 3132
Query 3147 CISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ + H +W FS R++ + S TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVFS--YCRKLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSG 3265
YL+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3266 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKS 3325
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3326 NHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSP 3385
+ +F V + L V+ + M+ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMRGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3386 SGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFY 3445
G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3446 GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3505
GP+ D Q Q D +VN LAWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPIQDYIQSVNFLAWLYAAILNNCNWFIQSDKCSVEDFNVWALSNGFSQV 3488
Query 3506 TQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSG 3565
D V + L++ TG+++ + A++K L +NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3566 VTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFA 3625
+ QS R KGT W++ + ++ +W++F ++ N F + + + A
Sbjct 3546 IKLQSKRTRLFKGTVCWIMASTFLFSCIITAFVKWTMFMYVTTNMF-SITFCALCVISLA 3604
Query 3626 MMFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
M+ VKHKH +L +++ P L T+ Y N +V ++ + WL S+ + D V+
Sbjct 3605 MLLVKHKHLYLTMYITPVLFTLLYNNYLVVYKHTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3685 YASAVVL-LILMTARTVYDD---GARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISV 3740
Y +++ ++ +T R++ D V L++V +L YK G+ L++ I + ++ S+
Sbjct 3664 YGMLLLVGMVFVTLRSINHDLFSFIMFVGRLISVFSLWYK---GSNLEEEILL--MLASL 3718
Query 3741 TSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLL 3800
Y+ M +A+ ++ V ++F ++ ++L Y F+GY +CY+GLF L+
Sbjct 3719 FGTYTWTTVLSMAVAK-VIAKWVAVNVLYFTDIPQIKIVLLCYLFIGYIISCYWGLFSLM 3777
Query 3801 NRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQS 3860
N FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QS
Sbjct 3778 NSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQS 3837
Query 3861 KMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLS 3920
K++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D + AFEK+ LL VL +
Sbjct 3838 KLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFEKLAQLLIVLFA 3897
Query 3921 MQGAVD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS- 3973
AVD I ++C++ + LQA+ SEF ++ S+ + A++ ++A +G +
Sbjct 3898 NPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARFSGSAN 3957
Query 3974 EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTML 4033
+ LK+L+K+ N+AKS ++RD A+ +KLE+MAD A+T MYK+AR DK++KV SA+QTML
Sbjct 3958 QQQLKQLEKACNIAKSAYERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTML 4017
Query 4034 FTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYAS 4093
F+M+RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA
Sbjct 4018 FSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTYAG 4077
Query 4094 ALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQ 4151
+W+IQ + D+D QL+EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4078 NVWQIQTIQDSDGTNKQLNEISDDCN----WPLVIIANRYNEVSATVLQNNELMPAKLKI 4133
Query 4152 MSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEP 4211
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+P
Sbjct 4134 QVVNSGPDQTCNTPTQC--YYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDP 4190
Query 4212 PCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCA 4271
PC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CA
Sbjct 4191 PCKFTVQDAKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCA 4250
Query 4272 FAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCR 4331
F+VD K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR
Sbjct 4251 FSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCR 4310
Query 4332 CHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPML 4391
++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +
Sbjct 4311 ARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCRVCGFWRDGSCSCVS-TDTTV 4368
Query 4392 QSADAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQE 4450
QS D +FLNRV G S ARL PC +G STDV RAFDIYN VAG LK NCCRFQ
Sbjct 4369 QSKDT-NFLNRVRGASVDARLVPCASGLSTDVQLRAFDIYNASVAGIGLHLKVNCCRFQR 4427
Query 4451 KDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQR 4510
DE+ + +D +FVVKR + Y E Y +KDC VA+HDFF F ++G VPHI R+
Sbjct 4428 VDENGDKLDQFFVVKRTDLTIYNREMKCYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKD 4487
Query 4511 LTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANL 4570
LTKYTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY L
Sbjct 4488 LTKYTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKL 4547
Query 4571 GERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYY 4630
G +AL+ +F D + G+VGVLTLDNQDLNG WYDFGD++ PG GV + DSYY
Sbjct 4548 GPIFNRALVSATEFADKLVEVGLVGVLTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYY 4607
Query 4631 SLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNC 4690
S +MP+LT+ AL E +V+ Y +DL++YDFT+ +L+LF++YFK+W YHPN
Sbjct 4608 SYIMPMLTMCHALDCELYVNN----AYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNT 4663
Query 4691 VNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQD 4750
V+C DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N D
Sbjct 4664 VDCQDDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMD 4723
Query 4751 VNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKD 4810
V+ H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+D
Sbjct 4724 VDTHRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQD 4783
Query 4811 FYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDK 4870
FYDF +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV K
Sbjct 4784 FYDFVLSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYK 4843
Query 4871 YFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPT 4930
YF+ YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT
Sbjct 4844 YFEIYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPT 4903
Query 4931 ITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGW 4990
+TQMNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW
Sbjct 4904 LTQMNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGW 4963
Query 4991 HNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANE 5050
+ML+ + DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH TCCS S RFYRLANE
Sbjct 4964 DDMLRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHETCCSQSDRFYRLANE 5023
Query 5051 CAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADK 5110
CAQVLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D
Sbjct 5024 CAQVLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDL 5083
Query 5111 YVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVAS 5170
+R LQ RLY +YR+ VD+ FV E+Y +L KHFSMMILSDD VVC+NS YAS+G +A+
Sbjct 5084 SIRALQKRLYSHVYRSDKVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIAN 5143
Query 5171 IKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRIL 5230
I F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYP+PSRIL
Sbjct 5144 ISAFQQVLYYQNNVFMSESKCWVEHDINNGPHEFCSQHTMLVKMDGDDVYLPYPNPSRIL 5203
Query 5231 GAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGH 5290
GAGCFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL YI+KL+++L
Sbjct 5204 GAGCFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLAYIKKLYNDLGNQ 5263
Query 5291 MLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLC 5350
+LD YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LC
Sbjct 5264 ILDSYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLC 5323
Query 5351 CKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCAN 5410
CKCCYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L N
Sbjct 5324 CKCCYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMN 5383
Query 5411 GQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFK 5470
G VFGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK
Sbjct 5384 GLVFGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFK 5443
Query 5471 LSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYG 5530
SY AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K +
Sbjct 5444 QSYASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELT 5503
Query 5531 DAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSS 5588
+ V YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F +
Sbjct 5504 NGVYYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQN 5560
Query 5589 NVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKY 5648
NV NYQ +GM++Y T+QGPPGTGKSH AIGLA++Y +AR+VYTA SHAAVDALCEKA K+
Sbjct 5561 NVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAVFYCTARVVYTAASHAAVDALCEKAYKF 5620
Query 5649 LPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDL 5708
L I+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+L
Sbjct 5621 LNINDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYEL 5680
Query 5709 SVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRC 5768
SV+NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RC
Sbjct 5681 SVINARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRC 5740
Query 5769 PAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNP 5828
P EIVDTVSALVY+NKLKA + S CFK++YKGV TH+ SSA+N QI ++ +FL NP
Sbjct 5741 PKEIVDTVSALVYENKLKAKNESSLLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANP 5800
Query 5829 AWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVA 5888
W KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVA
Sbjct 5801 LWHKAVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVA 5860
Query 5889 ITRAKVGILCIMSDRDLYDKLQFTSL---EIPRRNVATLQAENVTGLFKDCSKVITGLHP 5945
ITRAK GILC+MS+ L++ LQFT+L ++P+ +Q T LFKDCSK +G HP
Sbjct 5861 ITRAKKGILCVMSNMQLFEALQFTTLTLDKVPQAVETKVQCS--TNLFKDCSKSYSGYHP 5918
Query 5946 TQAPTHLSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEA 6004
AP+ L+VD K+K G GI +TY RLIS+MGFK++ ++GY +FIT+EEA
Sbjct 5919 AHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEA 5978
Query 6005 IRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAK 6064
++ VRAW+GFD EG HAT +++GTN PLQLGFSTG++ V TG + F + AK
Sbjct 5979 VKRVRAWVGFDAEGAHATLDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAK 6038
Query 6065 PPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFV 6124
PPG+QFKHLIPLM +G W+VVR +IVQM +D L +LSD VV V WA FELT ++YF
Sbjct 6039 APPGEQFKHLIPLMTRGHRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFA 6098
Query 6125 KIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDL 6184
K+G E +C +C +RAT +++ + Y CW HS+ DY+YNP ++D+QQWG+ G+L SNHDL
Sbjct 6099 KVGREISCNVCTKRATVYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDL 6158
Query 6185 YCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKA 6244
YC VH AHVAS DAIMTRCLAV++CF ++W +EYPII +EL IN +CR +Q +++KA
Sbjct 6159 YCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVILKA 6218
Query 6245 ALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTD 6304
A+L +++ + +DIGNPK I CV D ++KFYDAQP ++ L YS+ H D F D
Sbjct 6219 AMLCNRYTLCYDIGNPKGIACVK--DFDFKFYDAQPI---VKSVKTLLYSFEAHKDSFKD 6273
Query 6305 GVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNL 6364
G+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +L
Sbjct 6274 GLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFARAAFEHL 6333
Query 6365 KQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYN 6424
K +PFFYYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR YL++YN
Sbjct 6334 KPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYN 6393
Query 6425 MMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVY 6484
+AGF+ WVYK FD YNLWNTFT+LQSLENV +N+V GH+ GQ GE+P +IIN+ V
Sbjct 6394 TATTAGFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVV 6453
Query 6485 TKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDA 6544
TK+D DV +F N TT P NVA EL+AKR+++ PE+K+ NL +D+ VIWDY R++
Sbjct 6454 TKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARES 6513
Query 6545 PAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQ 6604
+T GVC TD+ L V FDGR +G + F+ + NGV I+ VK L
Sbjct 6514 IFCSNTYGVCMYTDLK------FIDKLNVLFDGRDNGAFEAFKRSNNGVYISTTKVKSLS 6567
Query 6605 PSVGPKQASLNGVTL--IGE-------AVKTQ-----FNYYKKVDGVVQQLPE------- 6643
GP +A LNGV + +G+ AV+ + F+ + + Q P+
Sbjct 6568 MIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNG 6627
Query 6644 --------------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVY 6689
T FTQSR + F R+ ME DF+ L D FI++Y LE YAFEHIVY
Sbjct 6628 KPGNVGGNDALSISTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVY 6687
Query 6690 GDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDL 6749
G+F+ +GGLHLLIGL +R + S +++F+ DS++ +YFITD ++G SK VC+VID+
Sbjct 6688 GNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDI 6747
Query 6750 LLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAM 6809
LLDDFV ++KS +L+ VSKVV V +D+ + FMLWC D V TFYP+LQ++ W+PG +M
Sbjct 6748 LLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSM 6807
Query 6810 PNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFG 6869
P LYK +E+ L NYG TLP G MMNVAKYTQLCQYLNT TLAVP NMRV+H G
Sbjct 6808 PVLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLG 6867
Query 6870 AGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDM 6929
AGS+KGVAPG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDM
Sbjct 6868 AGSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDM 6927
Query 6930 YDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWT 6989
YDP TKN+ + N SK+GFFTYIC I+ KLALGGSVAIKITE SWNA+LYKLMG+FA+WT
Sbjct 6928 YDPITKNIGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWT 6987
Query 6990 AFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFP 7049
F TN NASSSE FLIG NYL KP+ +IDG VMHANY+FWRN+ +YSLFDM+KFP
Sbjct 6988 VFCTNANASSSEGFLIGINYLCKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFP 7047
Query 7050 LKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
LKL GTAV++L+ QINDM+ SLL KG+L+IR+ N+ V D LVN
Sbjct 7048 LKLAGTAVINLRADQINDMVYSLLEKGKLLIRDTNKEVFVGDSLVN 7093
Score = 80.9 bits (198), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 79/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K VK VVVN AN ++ HGGGVA A+ A E+ + + +
Sbjct 1273 ITPNVCFVKGDIIKVSKLVKAEVVVNPANGHMVHGGGVAKAIAVAAGQQFVKETTNMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++FN ++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYVLLERVYKHFNNYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T + V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFD 1425
Score = 63.9 bits (154), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 60/242 (25%), Positives = 102/242 (42%), Gaps = 30/242 (12%)
Query 715 GLYRKCVKSRE----ETGLL----MPL------------KAPKEIIFLEGETLPTEVLTE 754
G R C+ R+ E GLL +PL KA ++ I+L+G +
Sbjct 732 GRRRICLSGRKIYEVERGLLHSSQLPLDVYDLTMPSQVQKAKQKPIYLKGSGSDFSLADS 791
Query 755 EVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFT 814
V + T L P E P V +CI + + + Y + + + +
Sbjct 792 VVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDDHVGLLDQAW 846
Query 815 LKGGAPTKVTFGDDTVIE--VQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFA 872
A +VTF + ++ + K + + +ELD + +LN C + V+ ++ EF
Sbjct 847 RVPCAGRRVTFKEQPTVKEIISMPKIIKVFYELDNDFNTILNTACGVFEVDDTVDMEEFY 906
Query 873 CVVADAVIKTLQPVSELL---TPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDE 929
VV DA+ + L P EL + L + +LFDE+GE A +YC+F P++
Sbjct 907 AVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNPLFLFDEAGEEVFAPKLYCAFTAPED 966
Query 930 DE 931
D+
Sbjct 967 DD 968
>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124
Score = 5395 bits (13994), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2773/5675 (49%), Positives = 3694/5675 (65%), Gaps = 223/5675 (4%)
Query 1549 EVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIK 1608
+V + ++ LL+ + V TVD +N + V +G+ G + DG +VTK++
Sbjct 1543 KVASVSQIRALLA----NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVR 1598
Query 1609 PHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIK 1668
H+GK F+ + A D L +Y + L K W + K
Sbjct 1599 CSAIHKGKVFFQYSGLSAADLVAVTDAFGFDEPQLLKYYNMLGMCK-WPVVVCGNYFAFK 1657
Query 1669 WADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDV 1728
++NNCY+ A L LQ + LKF+ Q+A+ R+G+ F +L+LA + E D
Sbjct 1658 QSNNNCYINVACLMLQHLSLKFHKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDS 1717
Query 1729 RETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCT 1788
+ M + + A+L VCK CG +Q KGV+AVM+ GTL KG I CT
Sbjct 1718 TDFMRVVLREADLSGATCDFEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLAKGYTIACT 1776
Query 1789 CGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCI 1848
CG + + Q PF++ S P +L A+ +TG GHY H+ K
Sbjct 1777 CGNKLV-HCTQLNVPFLICSNKPEGKKLPDDV-VAANIFTGG-SLGHYTHVKCKPKYQLY 1833
Query 1849 DGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYF 1907
D ++K SE KG TD Y +N T + K T+ LD V C E +P L YY + Y+
Sbjct 1834 DACNVSKVSEAKGNFTDCLYLKNLKQTFSSKLTTFYLDDVKCVEYNPDLSQYYCESGKYY 1893
Query 1908 TEQPIDLVPNQPYPNAS--FDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLN 1964
T +PI + + + NFK V +I A+ N G+ E K+T +P
Sbjct 1894 T-KPIIKAQFRTFEKVEGVYTNFKLVGHSI--AEKFNAKLGFDCNSPFTEYKITEWPTAT 1950
Query 1965 GDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVE 2020
GDVV Y + G KP++W H + TY +P+ C ++ PV+
Sbjct 1951 GDVVLASDDLYVSRYSGGCVTFGKPVIWLGHEEASLKSLTYFNRPSVVC-ENKFNVLPVD 2009
Query 2021 TSNSFD-------VLKSEDAQG---MDNLACEDLKPVSEEVVEN---------PTIQKDV 2061
S D VL + G A E S+ VV+ DV
Sbjct 2010 VSEPTDKGPVPAAVLVTGALSGAATAPGTAKEQKVCASDSVVDQVVSGFLSDLSGATVDV 2069
Query 2062 LECNV----KTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVL 2117
E + K +V +++ + K+ + + D+ ++ + NELSR+
Sbjct 2070 KEVKLNGVKKPIKVEDSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWMANELSRL- 2128
Query 2118 GLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNR-------------V 2164
VNS T+ Y K + K+V ++ R +
Sbjct 2129 ------------VNS---PTVREYVKWGMTKIVIPAKLVLLRDEKQEFVAPKVVKAKVIA 2173
Query 2165 CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFS 2224
C + + +FF F N+ K T +A K C A N L++ N++
Sbjct 2174 CYSAVKWFFLYCFSWIKF----NTDNKVIYTTEVAS---KLTFNLCCLAFKNALQTFNWN 2226
Query 2225 KLIN--------IIIWF-------LLLSVCLGSLIYSTAALGVLMS----NLGMPSYCTG 2265
+ ++WF +L L ++ + +G +++ G+ + C
Sbjct 2227 VVSRGFFLVATVFLLWFNFLYANVILSDFYLPNIGFFPTFVGQIVAWVKTTFGIFTLCDL 2286
Query 2266 YR---EGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLT 2319
Y+ GY +S +C GS+ C +C SG D LD Y ++ +Q + SF + ++
Sbjct 2287 YQVSDVGYRSS-------FCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRVSFDY-IS 2338
Query 2320 AFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPI 2377
F LV E + Y L+T FY L MQL ++ F+ + W + + M P
Sbjct 2339 LFKLVVELVIGYSLYTVCFYPLFGLIGMQLLTTWLPEFFMLETMHWSARFFVFVANMLPA 2398
Query 2378 SAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVY 2437
++R YI + Y ++ HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V
Sbjct 2399 FTLLRFYIVVTAMYKIFCLCRHVMYGCSRPGCLFCYKRNRSVRVKCSTVVGGTLRYYDVM 2458
Query 2438 ANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVK 2497
ANGG GFC H WNC+NC F G+TFI+ E A DLS + KRP+NPTD + Y+V V
Sbjct 2459 ANGGTGFCAKHQWNCLNCSAFGPGNTFITHEAAADLSKELKRPVNPTDSAYYLVTEVKQV 2518
Query 2498 NGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSA 2557
S+ L++++ GQ+ Y+ S S FV+++ L + KG +V+V + ++ +++ +A
Sbjct 2519 GCSMRLFYERDGQRVYDDVSASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNA 2576
Query 2558 SVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAE 2617
+V+Y+Q + +P+LL+++ L++ V+ MFD YV++ +V + L + V A
Sbjct 2577 AVFYAQSLYRPMLLVEKKLITTANTGLSVSQTMFDLYVDSLLGVLDVDRKSLTSFVNAAH 2636
Query 2618 AELAKNVSLDNVLSTFISAARQG-FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLT 2676
L + V L+ V+ TFI AR+ +DSDVETK + + + + + ++ T +SCNN + T
Sbjct 2637 NSLKEGVQLEQVMDTFIGCARRKCAIDSDVETKSITKSIMSAVNAGVDFTDESCNNLVPT 2696
Query 2677 YNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKN 2736
Y K + + DLG I +A+H+ A VAK+ N+A IW+V F LS L+ ++R A K
Sbjct 2697 YVKSDTIVAADLGVLIQNNAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKT 2756
Query 2737 NLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVM 2796
L KLT V ++TT +LKGG + + L+ L V L+ V + + P + +
Sbjct 2757 GLKIKLTYNKQEANVPILTTPFSLKGGAVFSKVLQWLFVVNLICFIV---LWALMPTYAV 2813
Query 2797 SKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLI 2854
K +K ID GV RD+ TD CFANK FD W+ G Y N +ACP++
Sbjct 2814 HKSDMQLPLYASFKVIDNGVLRDVTVTDACFANKFIQFDQWYESTFGLVYYRNSRACPVV 2873
Query 2855 AAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACV 2914
AVI +++G+ + +P +LR LHF+ F+ CYTP I Y +F S CV
Sbjct 2874 VAVIDQDIGYTLFNVPTKVLR-YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCV 2932
Query 2915 LAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSV 2973
L++ CT+ A G P PYCY ++ + Y+SL P RY L + + I+FP EG V
Sbjct 2933 LSSLCTMLAHADGTPHPYCYTEGIMHNASLYDSLAPHVRYNLANSNGYIRFPEVVSEGIV 2992
Query 2974 RVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTP 3033
R+V T YCR G CE +E GVC + + WVLNN YYR++PG FCG +A +L+ +
Sbjct 2993 RIVRTRSMTYCRVGLCEDAEEGVCFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGG 3052
Query 3034 LIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLC 3093
L++PI ++AS VAG I+AI+V YY ++ +RAFG+Y+ VV N +++ ++F +L
Sbjct 3053 LVRPIDFFALTASSVAGAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLF 3112
Query 3094 LTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHF 3153
+ VY L +Y+ Y Y T Y +++S + H+QW+VM+ ++P W I Y+ + + H
Sbjct 3113 VFQVYPTLSCLYACFYFYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHA 3172
Query 3154 YWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNK 3213
W FS R++ S TFEE +L TF++ KE Y KL++ V +NRYL+LYNK
Sbjct 3173 LWLFS--YCRKLGTEVRSDGTFEEMSLTTFMITKESYCKLKNSV--SDVAFNRYLSLYNK 3228
Query 3214 YKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFP 3272
Y+YFSG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S+T++ LQSG KM FP
Sbjct 3229 YRYFSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVFP 3288
Query 3273 SGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQ 3332
+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R + +F V
Sbjct 3289 TSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYSNLLCRVISSDFCVM 3348
Query 3333 AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCA 3392
+G + L V+ + MQ +L L V NP TPKY F ++PG+TF+VLA YNG G +
Sbjct 3349 SGRMSLTVMSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGKSQGAFHVT 3408
Query 3393 MRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQ 3452
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+ D Q
Sbjct 3409 MRSSYTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQ 3468
Query 3453 TAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDI 3512
Q D T TVNV+AWLYAA++N WF+ + +L +FN+ AM + + D V
Sbjct 3469 VVQLPVQDYTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV-- 3526
Query 3513 LGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAV 3572
L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q +GV QS
Sbjct 3527 LDALASMTGVTVEQILAAIKRLY-SGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKR 3585
Query 3573 KRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHK 3632
R +KGT W+L + L ++ +W++F ++ + L + + +FAM+ VKHK
Sbjct 3586 TRVVKGTCCWILASTLLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLVKHK 3644
Query 3633 HAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL 3691
H +L +F++P L T+ Y N +V S+ WL ++ + D V+Y VVL
Sbjct 3645 HLYLTMFIMPVLCTLFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLY--GVVL 3701
Query 3692 LILM---TARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
L+ M T R++ D ++ + +++LV Y+G L++ + ++ + S+ Y+
Sbjct 3702 LVAMVFVTMRSINHDVFSVMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW-- 3757
Query 3749 TTVMFLARG-IVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
TT++ LA ++ + ++F ++ ++L Y +GY C CY+G+ LLN FR+
Sbjct 3758 TTMLSLATAKVIAKWLAVNVLYFTDVPQVKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMP 3817
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
LGVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC
Sbjct 3818 LGVYNYKISVQELRYMNANGLRPPRNSFEALVLNFKLLGIGGVPVIEVSQIQSRLTDVKC 3877
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD- 3926
+VVLL+ LQ L + SSSKLW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3878 VNVVLLNCLQHLHIASSSKLWQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDS 3937
Query 3927 -----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKL 3980
I ++ ++ + + LQA+ SEF ++ S+ + A++ ++A A+G + + +K+L
Sbjct 3938 KCLASIEEVSDDYVRDSTVLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQL 3997
Query 3981 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4040
+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKL
Sbjct 3998 EKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKL 4057
Query 4041 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQ 4100
DN ALN+I++NA GCVPLN IP T+ L +++PD + D TYA +W IQ
Sbjct 4058 DNQALNSILDNAVKGCVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQS 4117
Query 4101 VVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGT 4158
+ DAD + QL+EI + N+ WPL++ A R N S+V LQNNEL P LR +G+
Sbjct 4118 IQDADGAVKQLNEIDV----NITWPLVIAANRHNEVSSVVLQNNELMPQKLRTQVVNSGS 4173
Query 4159 TQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTD 4218
T YYNTT G+ V A+LSD LK+ + K DG + EL+PPC+F
Sbjct 4174 DMNCNTPTQ--CYYNTTGMGKIVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQ 4230
Query 4219 TPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK 4278
KG K+KYLYF+KG N L RG V+G+L++TVRLQAG ATE +NS + S CAF+VD K
Sbjct 4231 DVKGLKIKYLYFVKGCNTLARGWVVGTLSSTVRLQAGTATEYASNSAIRSLCAFSVDPKK 4290
Query 4279 AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPN 4338
Y DY+ GG P+TNCVKMLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+
Sbjct 4291 TYLDYIQQGGAPVTNCVKMLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPD 4350
Query 4339 PKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQS 4398
G C L+GK+VQ+P DPV + L + VC VCG W+ CSC QS D +
Sbjct 4351 VDGLCKLRGKFVQVPLG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVGTGS-QFQSKDT-N 4407
Query 4399 FLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNL 4457
FLNRV G S ARL PC +G TDV RAFDI N AG + K NCCRFQ DED N
Sbjct 4408 FLNRVRGTSVNARLVPCASGLDTDVQLRAFDICNANRAGIGLYYKVNCCRFQRADEDGNT 4467
Query 4458 IDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMA 4517
+D +FV+KR Y E+ Y L K+C VA+H+FF F ++G VPHI R+ L+KYTM
Sbjct 4468 LDKFFVIKRTNLEVYNKEKECYELTKECGVVAEHEFFTFDVEGSRVPHIVRKDLSKYTML 4527
Query 4518 DLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQA 4577
DL YALRHFD +C TLKEIL+TY CD+ YF KKDWYDFVEN DI+ VY LG +A
Sbjct 4528 DLCYALRHFDRNDCSTLKEILLTYAECDESYFQKKDWYDFVENSDIINVYKKLGPIFNRA 4587
Query 4578 LLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPIL 4637
LL T +F D + AG+VGVLTLDNQDL G WYDFGDF++T PG GV V DSYYS +MP+L
Sbjct 4588 LLNTAKFADTLVEAGLVGVLTLDNQDLYGQWYDFGDFVKTVPGCGVAVADSYYSYMMPML 4647
Query 4638 TLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDR 4697
T+ AL +E ++ Y ++DL++YDFT+ +L+LF++YFKYW TYHPN C DDR
Sbjct 4648 TMCHALDSELFIN----GTYREFDLVQYDFTDFKLELFNKYFKYWSMTYHPNTCECEDDR 4703
Query 4698 CILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSR 4757
CI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H R
Sbjct 4704 CIIHCANFNILFSMVLPKTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYR 4763
Query 4758 LSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVS 4817
LS K+LL+YAADPA+H AS + LLD RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +S
Sbjct 4764 LSLKDLLLYAADPALHVASASALLDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILS 4823
Query 4818 KGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDG 4877
KG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV+KYF+ YDG
Sbjct 4824 KGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVNKYFEIYDG 4883
Query 4878 GCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLK 4937
GCI A QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLK
Sbjct 4884 GCIPATQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEVYAYTKRNVLPTLTQMNLK 4943
Query 4938 YAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTV 4997
YAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ +
Sbjct 4944 YAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRL 5003
Query 4998 YSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSE 5057
DV++P LMGWDYPKCDRAMPN+LRI++SLVLARKH +CCS + RFYRLANECAQVLSE
Sbjct 5004 IKDVDSPVLMGWDYPKCDRAMPNILRIISSLVLARKHDSCCSHTDRFYRLANECAQVLSE 5063
Query 5058 MVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQH 5117
+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ
Sbjct 5064 IVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQK 5123
Query 5118 RLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSV 5177
RLY +YR VD FVNE+Y +L KHFSMMILSDD VVC+NS +AS+G +A+I F+ V
Sbjct 5124 RLYSNVYRADHVDPAFVNEYYEFLNKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQV 5183
Query 5178 LYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVD 5237
LYYQNNVFMSEAKCW ETD+ KGPHEFCSQHTMLVK D VYLPYPDPSRILGAGCFVD
Sbjct 5184 LYYQNNVFMSEAKCWVETDIEKGPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVD 5243
Query 5238 DIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSV 5297
D++KTD L+IERFVSLAIDAYPL H N EY +VF +YL+YI+KL+++L +LD YSV
Sbjct 5244 DLLKTDSVLLIERFVSLAIDAYPLVYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSYSV 5303
Query 5298 MLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDH 5357
+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC YDH
Sbjct 5304 ILSTCDGQKFTDETFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDH 5363
Query 5358 VISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLY 5417
V+ST HK VLSV+PYVCN+PGCDV DVT+LYLGGMSYYC+ HKP SF L NG VFGLY
Sbjct 5364 VMSTDHKYVLSVSPYVCNSPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLY 5423
Query 5418 KNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIAT 5477
K +C GS + DFN IA+C WT DY+LAN CTERLKLFAAET KATEE+FK Y AT
Sbjct 5424 KQSCTGSPYIEDFNKIASCKWTEVDDYVLANECTERLKLFAAETQKATEESFKQCYASAT 5483
Query 5478 VREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRG 5537
+RE++SDREL LSWE+GK RPPLN+NYVFTGY T N K +GEY F+K + + V YR
Sbjct 5484 IREIVSDRELILSWEIGKVRPPLNKNYVFTGYHFTSNGKTVLGEYVFDKSELTNGVYYRA 5543
Query 5538 TTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQK 5595
TTTYKL+VGD F+LTSH V LSAPTLVPQE+Y +R +Y ++ + F +NV NYQ
Sbjct 5544 TTTYKLSVGDVFILTSHAVSSLSAPTLVPQENYTSIRFASVY---SVPETFQNNVPNYQH 5600
Query 5596 VGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS 5655
+GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+
Sbjct 5601 IGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLNINDCT 5660
Query 5656 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5715
RI+PA+ RV+C+DKFKVN T +YVF T+NALPE DI+V DE+SM TNY+LSV+N+R+
Sbjct 5661 RIVPAKVRVDCYDKFKVNDTTRKYVFTTINALPELVTDIIVVDEVSMLTNYELSVINSRV 5720
Query 5716 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5775
RAKHYVYIGDPAQLPAPR LL KGTLEP YFNSV +LM +GPD+FLGTC RCP EIVDT
Sbjct 5721 RAKHYVYIGDPAQLPAPRVLLNKGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDT 5780
Query 5776 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVF 5835
VSALVY NKLKA D S+ CFK++YKG TH+ SSA+N QI ++ +FL NP+W AVF
Sbjct 5781 VSALVYHNKLKAKNDNSSMCFKVYYKGQTTHESSSAVNMQQIYLISKFLKANPSWSNAVF 5840
Query 5836 ISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVG 5895
ISPYNSQN VA ++LGL TQTVDS+QGSEYD+VI++QT ETAHS NVNRFNVAITRAK G
Sbjct 5841 ISPYNSQNYVAKRVLGLQTQTVDSAQGSEYDFVIYSQTAETAHSVNVNRFNVAITRAKKG 5900
Query 5896 ILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVD 5955
ILC+MS L++ L F++L + + N LQ T LFKDCS+ G HP AP+ L+VD
Sbjct 5901 ILCVMSSMQLFESLNFSTLTLDKINNPRLQC--TTNLFKDCSRSYAGYHPAHAPSFLAVD 5958
Query 5956 TKFKTEG-LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGF 6014
K+K G L V + +TY RLIS+MGFK++ ++GY +FITR+EAIR VRAW+GF
Sbjct 5959 DKYKVGGDLAVCLNVADSAVTYSRLISLMGFKLDLTLDGYCKLFITRDEAIRRVRAWVGF 6018
Query 6015 DVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHL 6074
D EG HATR+++GTN PLQLGFSTG++ V TG + F + A+ PPG+QFKHL
Sbjct 6019 DAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGMFAERDGYVFKKAVARAPPGEQFKHL 6078
Query 6075 IPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCL 6134
+PLM +G W+VVRI+IVQMLSD L +L+D VV V WA FELT ++YF K+G E C +
Sbjct 6079 VPLMSRGQKWDVVRIRIVQMLSDHLVDLADSVVLVTWAASFELTCLRYFAKVGKEVVCSV 6138
Query 6135 CDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHV 6194
C++RATCF++ + Y CW HS DY+YNP ++D+QQWG+TG+L SNHDL C VH AHV
Sbjct 6139 CNKRATCFNSRTGYYGCWRHSYSCDYLYNPLIVDIQQWGYTGSLTSNHDLICSVHKGAHV 6198
Query 6195 ASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVL 6254
AS DAIMTRCLAVH+CF K V+W++EYPII +E+ +N +CR +Q ++ +AA+L +++ V
Sbjct 6199 ASSDAIMTRCLAVHDCFCKSVNWSLEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVC 6258
Query 6255 HDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNV 6314
+DIGNPK + CV D +KFYDA P +++ Y Y H D+F DG+C+FWNCNV
Sbjct 6259 YDIGNPKGLACVKGYD--FKFYDASPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNV 6313
Query 6315 DRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSD 6374
D+YPAN++VCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD
Sbjct 6314 DKYPANAVVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTSPFTRAAFENLKPMPFFYYSD 6373
Query 6375 SPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLW 6434
+PC +DYVPL+SATCITRCNLGGAVC HA +YR YL++YN +AGF+ W
Sbjct 6374 TPCVYMEGMESKQVDYVPLRSATCITRCNLGGAVCLKHAEDYREYLESYNTATTAGFTFW 6433
Query 6435 VYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVEL 6494
VYK FD YNLWNTFTRLQSLENV +N+VN GHFDG+ GE+P ++I V K+ DV +
Sbjct 6434 VYKTFDFYNLWNTFTRLQSLENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVV 6493
Query 6495 FENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVC 6554
F+N T P NVA EL+AKR+I+P PE+K+ NL +D+ + V+WDY +D+ ST VC
Sbjct 6494 FKNNTPFPTNVAVELFAKRSIRPHPELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVC 6553
Query 6555 SMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL 6614
TD+ L V FDGR +G ++ F+ R+GV I +K L GP++A L
Sbjct 6554 KYTDL------QCIESLNVLFDGRDNGALEAFKKCRDGVYINTTKIKSLSMIKGPQRADL 6607
Query 6615 NGVTL--IGEA-VKTQFNYYKKVDGVV-----------QQLPE----------------- 6643
NGV + +G++ V+ F + D V+ + P+
Sbjct 6608 NGVVVEKVGDSDVEFWFAMRRDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEAL 6667
Query 6644 ---TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGL 6700
T FTQSR L F PRS+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGL
Sbjct 6668 ARGTIFTQSRFLSSFAPRSEMEKDFMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGL 6727
Query 6701 HLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKS 6760
HLLIGLA+R ++S +++F+P DS++ +YFITD +GSSK VC+VIDLLLDDFV+I+KS
Sbjct 6728 HLLIGLARRQQKSNLVIQEFVPYDSSIHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKS 6787
Query 6761 QDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLL 6820
+L+ VSKVV V +D+ + FMLWC + V TFYP+LQ++ W+PG MP LYK L
Sbjct 6788 LNLNCVSKVVNVNVDFKDFQFMLWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPL 6847
Query 6821 EKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGT 6880
E+ +L NYG TLP G +MNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAPG+
Sbjct 6848 ERVNLWNYGKPITLPTGCLMNVAKYTQLCQYLNTTTLAVPANMRVLHLGAGSDKDVAPGS 6907
Query 6881 AVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKE 6940
AVLRQWLP G++LVD+D+N FVSD+ ++ G+C T+ A +WDLIISDMYDP TKN+ +
Sbjct 6908 AVLRQWLPAGSILVDNDINPFVSDSVASYYGNCITLPIACQWDLIISDMYDPLTKNIGEY 6967
Query 6941 NDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSS 7000
N SK+GFFTY+C I+ KLALGGSVAIKITE SWNA+LY LMG FA+WT F TNVNASSS
Sbjct 6968 NVSKDGFFTYLCHLIRDKLALGGSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSS 7027
Query 7001 EAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSL 7060
E FLIG N+L + R +IDG MHANY+FWRN+ +YSLFDMSKFPLK+ GTAV+SL
Sbjct 7028 EGFLIGINWLNRTRTEIDGKTMHANYLFWRNSTMWNGGAYSLFDMSKFPLKVAGTAVVSL 7087
Query 7061 KEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
K QIND++LSL+ KG+L++R+ + V D LVN
Sbjct 7088 KPDQINDLVLSLIEKGKLLVRDTRKEVFVGDSLVN 7122
Score = 71.6 bits (174), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 60/183 (33%), Positives = 83/183 (45%), Gaps = 21/183 (11%)
Query 819 APTKVTFGDD-TVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVAD 877
A KV F D V E+ + + I F LD D VL++ CS + V+ ++E VV D
Sbjct 832 AGKKVEFNDKPKVKEIPSTRKIKINFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLD 891
Query 878 AVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEG 934
AV TL P E + T + L+ + YLFDE GE +A MYCSF PD++
Sbjct 892 AVESTLSPCKEHDVIGTKVCALLNRLAEDYVYLFDEGGEEVIAPKMYCSFSAPDDE---- 947
Query 935 DCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGS 994
DC + + + + DD SAAL + QEED + Q V + D
Sbjct 948 DCVAADVVDADENQGDDADD-----------SAALV-TDTQEEDGV-AKGQVGVAESDAR 994
Query 995 EDN 997
D
Sbjct 995 LDQ 997
Score = 59.3 bits (142), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 52/154 (34%), Positives = 82/154 (53%), Gaps = 4/154 (3%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV D+++ ++V V+VN AN + HG GVAGA+ KA + E+ D +
Sbjct 1267 ITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKSFIKETADMVKN 1326
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENFNQHEVLLAPLLS 1150
G +VG +G NL K L++VGP+ +G Q L+ AY++ N+ + ++ L+S
Sbjct 1327 QGVCQVGECYESTGGNLCKTVLNIVGPDA-RGHGKQCYSFLERAYQHINKCDDVVTTLIS 1385
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
AGIF SL + V NV L +K+ +D
Sbjct 1386 AGIFSVPTDVSLTYLIGVVTKNVILVSNNKDDFD 1419
Score = 40.4 bits (93), Expect = 0.91, Method: Compositional matrix adjust.
Identities = 84/343 (24%), Positives = 131/343 (38%), Gaps = 70/343 (20%)
Query 59 GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEI 114
GVLP+ +F + T HV +L + +G+ G +G +G VP V I
Sbjct 120 GVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCLG-NGRFIGWFVP-VTAI 177
Query 115 PVAYRK-------VLLRKNGNKG---AGGHSYGADLKSFDLGDELGTDPYEDFQENWNTK 164
P AY K +LLRK GNKG +G + +D E D E+ N K
Sbjct 178 P-AYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE---DACEEVHLNPKGK 233
Query 165 HSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDT 224
+S L++ G ++D C G + ++D CTL E +
Sbjct 234 YSRK-AYALLKGYRGVKSILFLDQYGCDYTGRLAKGLEDY------GDCTLEEMKELFP- 285
Query 225 KRGVYC-CREHEHEIAWYTERSEKS-YELQTPFEIKLAKKF-----DTFNGEC----PNF 273
V+C ++E +AW+ +R ++ LQT I+ D +G+ P
Sbjct 286 ---VWCDSLDNEVVVAWHVDRDPRAVMRLQTLATIRSIGYVGQPTEDLVDGDVVVREPAH 342
Query 274 VFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQT 333
+ N+I+K + PR+ + L Y +S E C T + CD T +
Sbjct 343 LLAANAIVKRL-PRLVETML----------YTDSSVTE---FCYKTKL-CDCGFITQFGY 387
Query 334 GDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNS 376
D C+F G++P N + CP C S
Sbjct 388 VDCCGDACDF-------------RGWVPGNMMDGFLCPGCSKS 417
>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094
Score = 5394 bits (13993), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2748/5620 (49%), Positives = 3697/5620 (66%), Gaps = 184/5620 (3%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + + D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTV--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLK-PVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
D K P +++ ++K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAKEPKEINIIKLSGVKKPF--------KVEDSVIVNDDTSEIKYVKSLSIVDVYDMWL 2079
Query 2101 DNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNI 2156
++ N LSR + + T+ G+ V S+P D + KP N VV N
Sbjct 2080 TGCRCVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNK 2137
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
++ C N ++ + F LL + K T +A + + +F
Sbjct 2138 ISACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFL 2188
Query 2217 YLKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLG-MPSYCTGYREGYLNS 2273
K ++ II I+ L + ++I+S + +G +P++ + N+
Sbjct 2189 TFKWSVVARGACIIATIFLLWFNFIYANVIFS----DFYLPKIGFLPTFVGKIAQWIKNT 2244
Query 2274 TN-VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTA 2320
+ VTI YC GSI C CL+G D LD Y +++ +Q ++ D A
Sbjct 2245 FSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRA 2299
Query 2321 F-------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINL 2371
F +V E ++Y L+T +FY L +Q+ ++ F+ ++ W + L+++L
Sbjct 2300 FVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSL 2359
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
M P +R YI ASF ++ + HV GC+ S C+ CYKRNR+ RV+C+TIV G+
Sbjct 2360 ANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMI 2419
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R + ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2420 RYYDAMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTV 2479
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEE 2551
V + L++D+ GQ+TY+ + S FV+ NL + K ++V+V + + ++
Sbjct 2480 TDVKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DK 2537
Query 2552 SSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKT 2611
++ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L
Sbjct 2538 ANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNA 2597
Query 2612 LVATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSC 2670
L+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SC
Sbjct 2598 LIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESC 2657
Query 2671 NNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIR 2730
NN + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2658 NNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLK 2717
Query 2731 SAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLI 2790
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2718 KACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLV-CFIG--LWCL 2774
Query 2791 TPVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTN 2847
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2775 MPTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2848 DKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTD 2907
ACP++ AV+ ++ G V +P +LR LHF+ SA G CYTP I Y++
Sbjct 2834 SMACPIVVAVVDQDFGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2908 FATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPN 2966
F S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2893 FYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRFPE 2952
Query 2967 TYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNL 3026
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L
Sbjct 2953 VLREGLVRIVRTRSMPYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3027 LTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL 3086
+ +F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ +V N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWC 3072
Query 3087 MSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYII 3146
++F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIS 3132
Query 3147 CISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ + H +W FS R++ + S TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVFS--YCRQLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSG 3265
YL+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3266 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKS 3325
KM P+ KVE C+V VT G TLNGLWL D VYCPRHVIC++ DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCIVSVTYGNMTLNGLWLGDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3326 NHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSP 3385
+ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3386 SGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFY 3445
G + MR ++TIKGSFL GSCGSV + I DCV F YMH +EL TG H GTD G+FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVVYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3446 GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3505
GP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQV 3488
Query 3506 TQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSG 3565
D V + L++ TG+++ + A++K L +NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKHL-KNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3566 VTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFA 3625
+ QS R +KG W++ + ++ +W++F ++ N L + + +
Sbjct 3546 IKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLT 3604
Query 3626 MMFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
M+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+
Sbjct 3605 MLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3685 YASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSN 3743
Y +++ ++ +T R++ + + V+++V Y G+ L++ I + ++ S+
Sbjct 3664 YGMLLLIGMVFVTLRSINQYLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGT 3721
Query 3744 YSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
Y+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N
Sbjct 3722 YTWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSL 3780
Query 3804 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMS 3863
FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++
Sbjct 3781 FRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLT 3840
Query 3864 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3923
DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL +
Sbjct 3841 DVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPA 3900
Query 3924 AVD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVV 3976
AVD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + +
Sbjct 3901 AVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQ 3960
Query 3977 LKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTM 4036
LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M
Sbjct 3961 LKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSM 4020
Query 4037 LRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALW 4096
+RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W
Sbjct 4021 VRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVW 4080
Query 4097 EIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSC 4154
+IQ + D+D QL EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4081 QIQTIQDSDGTNKQLHEISDDCN----WPLVIIANRHNEVSATALQNNELMPAKLKTQVV 4136
Query 4155 AAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCR 4214
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+
Sbjct 4137 NSGPDQTCNTPTQC--YYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCK 4193
Query 4215 FVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAV 4274
F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+V
Sbjct 4194 FTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSV 4253
Query 4275 DAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHI 4334
D K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR +
Sbjct 4254 DPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCRARV 4313
Query 4335 DHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA 4394
+HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS
Sbjct 4314 EHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSK 4371
Query 4395 DAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDE 4453
D +FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRFQ DE
Sbjct 4372 DT-NFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRFQRVDE 4430
Query 4454 DDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTK 4513
+ + +D +FVVKR + Y E Y +KDC VA+HDFF F ++G VPHI R+ LTK
Sbjct 4431 NGDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKDLTK 4490
Query 4514 YTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGER 4573
YTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY LG
Sbjct 4491 YTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKLGPI 4550
Query 4574 VRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLL 4633
+AL+ +F D + G+VG+LTLDNQDLNG WYDFGD++ PG GV + DSYYS +
Sbjct 4551 FNRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYYSYM 4610
Query 4634 MPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNC 4693
MP+LT+ AL E +V+ Y +DL++YDFT+ +L+LF++YFK+W YHPN V+C
Sbjct 4611 MPMLTMCHALDCELYVNN----AYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNTVDC 4666
Query 4694 LDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNL 4753
DDRCI+ CANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N DV+
Sbjct 4667 QDDRCIIRCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMDVDT 4726
Query 4754 HSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYD 4813
H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+DFYD
Sbjct 4727 HRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYD 4786
Query 4814 FAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFD 4873
F +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+
Sbjct 4787 FILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFE 4846
Query 4874 CYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQ 4933
YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQ
Sbjct 4847 IYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQ 4906
Query 4934 MNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNM 4993
MNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +M
Sbjct 4907 MNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDM 4966
Query 4994 LKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQ 5053
L+ + DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS S RFYRLANE AQ
Sbjct 4967 LRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLANEYAQ 5026
Query 5054 VLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVR 5113
VLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D +R
Sbjct 5027 VLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDLSIR 5086
Query 5114 NLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKN 5173
LQ RLY +YR+ VD+ FV E+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I
Sbjct 5087 ALQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIANISA 5146
Query 5174 FKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAG 5233
F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYPDPSRILGAG
Sbjct 5147 FQQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPDPSRILGAG 5206
Query 5234 CFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLD 5293
CFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL++EL +LD
Sbjct 5207 CFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNELGNQILD 5266
Query 5294 MYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKC 5353
YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC
Sbjct 5267 SYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKC 5326
Query 5354 CYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQV 5413
CYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L NG V
Sbjct 5327 CYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMV 5386
Query 5414 FGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSY 5473
FGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK SY
Sbjct 5387 FGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFKQSY 5446
Query 5474 GIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAV 5533
AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K + + V
Sbjct 5447 ASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELTNGV 5506
Query 5534 VYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVA 5591
YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F +NV
Sbjct 5507 YYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQNNVV 5563
Query 5592 NYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPI 5651
NYQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I
Sbjct 5564 NYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLNI 5623
Query 5652 DKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVV 5711
+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+
Sbjct 5624 NDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYELSVI 5683
Query 5712 NARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAE 5771
NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RCP E
Sbjct 5684 NARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRCPKE 5743
Query 5772 IVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWR 5831
IVDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL NP W
Sbjct 5744 IVDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANPLWH 5803
Query 5832 KAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITR 5891
KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITR
Sbjct 5804 KAVFISPYNSQNFAARRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITR 5863
Query 5892 AKVGILCIMSDRDLYDKLQFTSLEIPRRNVAT-LQAENVTGLFKDCSKVITGLHPTQAPT 5950
AK GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP AP+
Sbjct 5864 AKKGILCVMSNMQLFEALQFTTLTVDKVPQAVETRVQCSTNLFKDCSKSYSGYHPAHAPS 5923
Query 5951 HLSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVR 6009
L+VD K+K G GI +TY RL S+MGFK++ ++GY +FIT+EEA++ VR
Sbjct 5924 FLAVDDKYKATGDLAVCLGIGDSAVTYSRLTSLMGFKLDVTLDGYCKLFITKEEAVKRVR 5983
Query 6010 AWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGD 6069
AW+GFD EG HATR+++GTN PLQLGFSTG++ V TG + F + AK PPG+
Sbjct 5984 AWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAKAPPGE 6043
Query 6070 QFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPE 6129
QFKHLIPLM +G W+VVR +IVQM +D L +LSD VV V WA FELT ++YF K+G E
Sbjct 6044 QFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFAKVGRE 6103
Query 6130 RTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVH 6189
+C +C +RAT +++ + Y CW HS+ DY+YNP ++D+QQWG+ G+L SNHDLYC VH
Sbjct 6104 ISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDLYCSVH 6163
Query 6190 GNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLAD 6249
AHVAS DAIMTRCLAV++CF ++W +EYPII +EL IN +CR +Q +++KAA+L +
Sbjct 6164 KGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKAAMLCN 6223
Query 6250 KFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLF 6309
++ + +DIGNPKAI CV D ++KFYDAQP ++ L Y + H D F DG+C+F
Sbjct 6224 RYTLCYDIGNPKAIACVK--DFDFKFYDAQPIVK---SVKTLLYFFEAHKDSFKDGLCMF 6278
Query 6310 WNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPF 6369
WNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +LK +PF
Sbjct 6279 WNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHLKPMPF 6338
Query 6370 FYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISA 6429
FYYSD+PC +DYVPLKSATCITRCNL GAVC HA EYR YL++YN +A
Sbjct 6339 FYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLVGAVCLKHAEEYREYLNSYNTATTA 6398
Query 6430 GFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDG 6489
GF+ WVYK FD YNLWNTFT+LQSLENV +N+V GH+ GQ GE+P +IIN+ V K+D
Sbjct 6399 GFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDK 6458
Query 6490 VDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHIS 6549
DV +F N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY R++ +
Sbjct 6459 EDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSN 6518
Query 6550 TIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGP 6609
T GVC TD+ L V FDGR +G ++ F+ + NGV I+ VK L GP
Sbjct 6519 TYGVCMYTDLK------FIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGP 6572
Query 6610 KQASLNGVTL--IGE-------AVKTQ-----FNYYKKVDGVVQQLPE------------ 6643
+A LNGV + +G+ AV+ + F+ + + Q P+
Sbjct 6573 PRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVG 6632
Query 6644 --------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHS 6695
T FTQSR + F R+ ME DF+ L D FI++Y LE YAFEHIVYG+F+
Sbjct 6633 GNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQK 6692
Query 6696 QLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFV 6755
+GGLHLLIGL +R + S +++F+ DS++ +YFITD ++G SK VC+VID+LLDDFV
Sbjct 6693 IIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFV 6752
Query 6756 EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKM 6815
++KS +L+ VSKVV V +D+ + FMLWC D V TFY +LQ++ W+PG +MP LYK
Sbjct 6753 ALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYLRLQAASDWKPGYSMPVLYKY 6812
Query 6816 QRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKG 6875
+E+ L NYG TLP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGS+KG
Sbjct 6813 LNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSEKG 6872
Query 6876 VAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTK 6935
VAPG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDMYDP TK
Sbjct 6873 VAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMYDPITK 6932
Query 6936 NVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNV 6995
N+ + N SK+GFFTYIC I+ KLALGGSVAIKITE SWNA+LYKLMG+FA+WT F TN
Sbjct 6933 NIGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTVFCTNA 6992
Query 6996 NASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGT 7055
NASSSE FLIG NYLGKP+ +IDG VMHANY+FWRN+ +YSLFDM+KFPLKL GT
Sbjct 6993 NASSSEGFLIGINYLGKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFPLKLAGT 7052
Query 7056 AVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
AV++L+ QINDM+ SLL KG+L++R+ N+ V D +VN
Sbjct 7053 AVINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDSMVN 7092
Score = 84.0 bits (206), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T + V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFD 1425
Score = 72.0 bits (175), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 223/1004 (22%), Positives = 371/1004 (37%), Gaps = 173/1004 (17%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYAGKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E S+ L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSLDSL-GAAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F+++ I ++ S V +
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKN---IPRYASA-----VAQAFRS 709
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK + +S++ F + I + G+K+ + G + HS L +
Sbjct 710 VAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP K ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKTKQKPIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRCVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGK 958
+ + +LFDE+GE LA +YC+F P++D D EE E D
Sbjct 936 KLEDNSLFLFDEAGEEVLAPKLYCAFTAPEDD----DFLEESGVEEDDVEGEETD---LT 988
Query 959 PLEFGATSAALQPEEEQE--EDWLDDDSQQTVGQQDGSEDNQTT 1000
G A + EE E ED LDD ED Q +
Sbjct 989 VTSAGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDVQMS 1032
>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176
Score = 5381 bits (13958), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2770/5656 (49%), Positives = 3678/5656 (65%), Gaps = 220/5656 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ V TVD +N + V +G+ G + DG +VTK++ ++GK F+ +
Sbjct 1611 VDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIYKGKVFFQYSDLSEA 1670
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
+ A + D L +Y + L K W + K ++NNCY+ A L LQ +
Sbjct 1671 DLVAVKDAFGFDEPQLLKYYTMLGMCK-WPVVVCGNYFAFKQSNNNCYINVACLMLQHLS 1729
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G+ F +L+LA + E D + M + + A+L
Sbjct 1730 LKFPKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDSIDFMRVVLREADLSGATCN 1789
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
L VCK CG +Q KGV+AVM+ GTL +G I CTCG + + Q PF++
Sbjct 1790 LEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLVRGYNIACTCGSKLV-HCTQFNVPFLIC 1847
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S P +L A+ +TG GHY H+ K D + K SE KG TD
Sbjct 1848 SNTPEGRKLPDDVVA-ANIFTGG-SVGHYTHVKCKPKYQLYDACNVNKVSEAKGNFTDCL 1905
Query 1868 YKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--NAS 1924
Y +N T + T+ LD V C E P L YY + Y+T +PI + + +
Sbjct 1906 YLKNLKQTFSSVLTTFYLDDVKCVEYKPDLSQYYCESGKYYT-KPIIKAQFRTFEKVDGV 1964
Query 1925 FDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK V +I A+ LN G+ E K+T +P GDVV Y + G
Sbjct 1965 YTNFKLVGHSI--AEKLNAKLGFDCNSPFVEYKITEWPTATGDVVLASDDLYVSRYSSGC 2022
Query 1984 KLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVETSNSFDV-----------L 2028
KP+VW H + TY +P+ C ++ PV+ S D +
Sbjct 2023 ITFGKPVVWLGHEEASLKSLTYFNRPSVVC-ENKFNVLPVDVSEPTDKGPVPAAVLVTGV 2081
Query 2029 KSEDAQGMDNLACEDLKPVSE--------EVVENPTIQ-KDVLECNV----KTTEVVGDI 2075
DA +A E S EV + P++ DV E + K +V G +
Sbjct 2082 PGADASAGAGIAKEQKACASASVEDQVVTEVRQEPSVSAADVKEVKLNGVKKPVKVEGSV 2141
Query 2076 ILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPW 2135
++ + K+ + + D+ ++ + NELSR+ VNS
Sbjct 2142 VVNDPTSETKVVKSLSIVDVYDMFLTGCKYVVWTANELSRL-------------VNS--- 2185
Query 2136 DTIANYAKPFLNKVVSTTTNIVTRCLNR-------------VCTNYMPYFFTLLLQLCTF 2182
T+ Y K + K+V+ ++ R + C + +F F
Sbjct 2186 PTVREYVKWGMGKIVTPAKLLLLRDEKQEFVAPKVVKAKAIACYCAVKWFLLYCFSWIKF 2245
Query 2183 TRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLIN--------IIIW-- 2232
N+ K T +A K K C A N L++ N+S + ++W
Sbjct 2246 ----NTDNKVIYTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVFLLWFN 2298
Query 2233 FLLLSVCLGSL---------IYSTAALGVLMSNLGMPSYCTGYRE---GYLNSTNVTIAT 2280
FL +V L + + + G+ + C Y+ GY +S
Sbjct 2299 FLYANVILSDFYLPNIGPLPTFVGQIVAWFKTTFGVSTICDFYQVTDLGYRSS------- 2351
Query 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLTAFGLVAEWFLAYILFTRF 2337
+C GS+ C +C SG D LD Y ++ +Q + SF + ++ F LV E + Y L+T
Sbjct 2352 FCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRLSFDY-ISLFKLVVELVIGYSLYTVC 2410
Query 2338 FYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWK 2395
FY L + MQL ++ F+ + W L + + M P ++R YI + Y V+
Sbjct 2411 FYPLFVLIGMQLLTTWLPEFFMLETMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVYC 2470
Query 2396 SYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNC 2455
HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC+NC
Sbjct 2471 LCRHVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLNC 2530
Query 2456 DTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYER 2515
+++ G+TFI+ E A DLS + KRP+NPTD + Y V V S+ L++++ GQ+ Y+
Sbjct 2531 NSWKPGNTFITHEAAADLSKELKRPVNPTDSAYYSVTEVKQVGCSMRLFYERDGQRVYDD 2590
Query 2516 HSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQA 2575
+ S FV+++ L + KG +V+V + ++ +++ A+V+Y+Q + +P+L++++
Sbjct 2591 VNASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLGAAVFYAQSLYRPMLMVEKK 2648
Query 2576 LVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFIS 2635
L++ V+ MFD YV++ + +V + L + V A L + V L+ V+ TFI
Sbjct 2649 LITTANTGLSVSRTMFDLYVDSLLNVLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFIG 2708
Query 2636 AARQG-FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDC 2694
AR+ +DSDVETK + + + + + ++ T +SCNN + TY K + + DLG I
Sbjct 2709 CARRKCAIDSDVETKSITKSVMSAVNAGVDFTDESCNNLVPTYVKSDTIVAADLGVLIQN 2768
Query 2695 SARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVV 2754
+A+H+ A VAK+ N+A IW+V F LS L+ ++R A K L KLT V ++
Sbjct 2769 NAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQEANVPIL 2828
Query 2755 TTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDG 2814
TT +LKGG + + L+ L L+ V + + P + + K +K ID
Sbjct 2829 TTPFSLKGGAVFSRMLQWLFVANLICFIV---LWALMPTYAVHKSDMQLPLYASFKVIDN 2885
Query 2815 GVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGT 2872
GV RD++ TD CFANK FD W+ G Y N KACP++ AVI +++G + +P T
Sbjct 2886 GVLRDVSVTDACFANKFNQFDQWYESTFGLAYYRNSKACPVVVAVIDQDIGHTLFNVPTT 2945
Query 2873 ILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPY 2932
+LR LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P PY
Sbjct 2946 VLR-YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHPY 3004
Query 2933 CYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCER 2991
CY V+ + Y SL P RY L + I+FP EG VRVV T YCR G CE
Sbjct 3005 CYTGGVMHNASLYSSLAPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLCEE 3064
Query 2992 SEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGG 3051
+E G+C + + WVLNN YYR++PG FCG +A +L+ + L++PI ++AS VAG
Sbjct 3065 AEEGICFNFNRSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALTASSVAGA 3124
Query 3052 IVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLY 3111
I+AI+V YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L +Y+ Y Y
Sbjct 3125 ILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFY 3184
Query 3112 LTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVS 3171
T Y +++S + H+QW+VM+ ++P W I Y+ + + H W FS R++ S
Sbjct 3185 TTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFS--YCRKIGTEVRS 3242
Query 3172 FSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAAC 3231
TFEE AL TF++ KE Y KL++ V +NRYL+LYNKY+YFSG MDT +YREAAC
Sbjct 3243 DGTFEEMALTTFMITKESYCKLKNSV--SDVAFNRYLSLYNKYRYFSGKMDTAAYREAAC 3300
Query 3232 CHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTL 3290
LAKA+ F+ N+G+DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G TL
Sbjct 3301 SQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCIVSVTYGNMTL 3360
Query 3291 NGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVL 3350
NGLWLDD VYCPRHVIC+S DM +P+Y +LL R ++ +F V +G + L V+ + MQ C L
Sbjct 3361 NGLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSGRMSLTVMSYQMQGCQL 3420
Query 3351 KLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGS 3410
L V NP TPKY F ++PG+TF+VLA YNG P G + +R + TIKGSFL GSCGS
Sbjct 3421 VLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVTLRSSHTIKGSFLCGSCGS 3480
Query 3411 VGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAW 3470
VG+ + D V F YMH +EL TG H GTD GNFYGP+ D Q Q D T TVNV+AW
Sbjct 3481 VGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAW 3540
Query 3471 LYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAS 3530
LYAA+ N WF+ + +L +FN+ AM + + D V L L++ TG+ V + A+
Sbjct 3541 LYAAIFNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVLAA 3598
Query 3531 LKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTS 3590
+K L +G G+ ILGS +LEDE TP DV +Q +GV QS R IKGT W+L +
Sbjct 3599 IKR-LHSGFQGKQILGSCVLEDE-TPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTFLF 3656
Query 3591 LLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYF 3650
++ +W++F ++ + L + + +FAM+ +KHKH +L ++++P L T
Sbjct 3657 CSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLIKHKHLYLTMYIMPVLCTFYTN 3715
Query 3651 NMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILM---TARTVYDDGARR 3707
+V S+ WL ++ + D V+Y VVLL+ M T R++ D
Sbjct 3716 YLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLY--GVVLLVAMVFVTMRSINHDVFSI 3772
Query 3708 VWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARG-IVFMCVEYC 3766
++ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA ++ +
Sbjct 3773 MFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKWLAVN 3828
Query 3767 PIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQ 3826
++F ++ ++L Y +GY C CY+G+ LLN FR+ LGVY+Y +S QE RYMN+
Sbjct 3829 VLYFTDVPQIKLVLLSYLCIGYVCCCYWGILSLLNSIFRMPLGVYNYKISVQELRYMNAN 3888
Query 3827 GLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSK 3886
GL PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+SK
Sbjct 3889 GLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNSK 3948
Query 3887 LWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRAT 3940
LW C LHN+IL D + AF+K+ LL VL + AVD I ++ ++ + +
Sbjct 3949 LWQYCSTLHNEILATSDLSMAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNTV 4008
Query 3941 LQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQR 3999
LQA+ SEF ++ S+ + A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ R
Sbjct 4009 LQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVAR 4068
Query 4000 KLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPL 4059
KLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPL
Sbjct 4069 KLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPL 4128
Query 4060 NIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNS 4119
N IP T+ L +++PD + D TYA +W IQ + DAD + QL+EI ++++
Sbjct 4129 NAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDVNST 4188
Query 4120 PNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKG 4177
WPL++ A R N S V LQNNEL P LR +G+ T YYNTT
Sbjct 4189 ----WPLVIAANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQ--CYYNTTGT 4242
Query 4178 GRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNL 4237
G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L
Sbjct 4243 GKIVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNTL 4301
Query 4238 NRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKM 4297
RG V+G+L++TVRLQAG ATE +NS +LS CAF+VD K Y DY+ GG P+TNCVKM
Sbjct 4302 ARGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIKQGGVPVTNCVKM 4361
Query 4298 LCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCA 4357
LC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P
Sbjct 4362 LCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-I 4420
Query 4358 NDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGT 4416
DPV + L + VC VCG W+ CSC QS D +FLNR+ G S ARL PC +
Sbjct 4421 KDPVSYVLTHDVCQVCGFWRDGSCSCVGTGS-QFQSKDT-NFLNRIRGTSVNARLVPCAS 4478
Query 4417 GTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEE 4476
G TDV RAFDI N AG + K NCCRFQ DED N +D +FVVKR Y E+
Sbjct 4479 GLDTDVQLRAFDICNANRAGIGLYYKVNCCRFQRVDEDGNKLDKFFVVKRTNLEVYNKEK 4538
Query 4477 TIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKE 4536
Y L K+C VA+H+FF F ++G VPHI R+ L+K+TM DL YALRHFD +C TLKE
Sbjct 4539 ECYELTKECGVVAEHEFFTFDVEGSRVPHIVRKDLSKFTMLDLCYALRHFDRNDCSTLKE 4598
Query 4537 ILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGV 4596
IL+TY C++ YF KKDWYDFVENPDI+ VY LG +ALL T +F DA+ AG+VGV
Sbjct 4599 ILLTYAECEESYFQKKDWYDFVENPDIINVYKKLGPIFNRALLNTAKFADALVEAGLVGV 4658
Query 4597 LTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKP 4656
LTLDNQDL G WYDFGDF++T PG GV V DSYYS +MP+LT+ AL +E V+
Sbjct 4659 LTLDNQDLYGQWYDFGDFVKTVPGCGVAVADSYYSYMMPMLTMCHALDSELFVN----GT 4714
Query 4657 YIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPT 4716
Y ++DL++YDFT+ +L+LF +YFK+W TYHPN C DDRCI+HCANFN+LFS V P T
Sbjct 4715 YREFDLVQYDFTDFKLELFTKYFKHWSMTYHPNTCECEDDRCIIHCANFNILFSMVLPKT 4774
Query 4717 SFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAAS 4776
FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+LL+YAADPA+H AS
Sbjct 4775 CFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYRLSLKDLLLYAADPALHVAS 4834
Query 4777 GNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQ 4836
+ LLD RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +SKG KEGSSV+LKHFFF Q
Sbjct 4835 ASALLDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSVDLKHFFFTQ 4894
Query 4837 DGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGF 4896
DGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV+KYF+ Y+GGCI A QVIVNN DKSAG+
Sbjct 4895 DGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVNKYFEIYEGGCIPATQVIVNNYDKSAGY 4954
Query 4897 PFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICS 4956
PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI S
Sbjct 4955 PFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILS 5014
Query 4957 TMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDR 5016
TMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPKCDR
Sbjct 5015 TMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPKCDR 5074
Query 5017 AMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGD 5076
AMPN+LRI++SLVLARKH +CCS + RFYRLANECAQVLSE+VMCGG YVKPGGTSSGD
Sbjct 5075 AMPNILRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLSEIVMCGGCYYVKPGGTSSGD 5134
Query 5077 ATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNE 5136
ATTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD FV+E
Sbjct 5135 ATTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVSE 5194
Query 5137 FYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETD 5196
+Y +L KHFSMMILSDD VVC+NS +AS+G +A+I F+ VLYYQNNVFMSEAKCW ETD
Sbjct 5195 YYEFLNKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQVLYYQNNVFMSEAKCWVETD 5254
Query 5197 LTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAI 5256
+ KGPHEFCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFVSLAI
Sbjct 5255 IEKGPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFVSLAI 5314
Query 5257 DAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAM 5316
DAYPL H N EY +VF +YL+YI+KL+++L +LD YSV+L+ + ++ + FY+ M
Sbjct 5315 DAYPLVYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSYSVILSTCDGQKFTDETFYKNM 5374
Query 5317 YTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNA 5376
Y VLQ+VGACV+C+SQTSLRCG+CIR+P LCCKC YDHV+ST HK VLSV+PYVCN+
Sbjct 5375 YLRSAVLQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVLSVSPYVCNS 5434
Query 5377 PGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATC 5436
PGCDV DVT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS + DFN IA+C
Sbjct 5435 PGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYIEDFNKIASC 5494
Query 5437 DWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKP 5496
WT DY+LAN CTERLKLFAAET KATEE FK Y AT+RE++SDREL LSWE+GK
Sbjct 5495 KWTEVDDYVLANECTERLKLFAAETQKATEEAFKQCYASATIREIVSDRELILSWEIGKV 5554
Query 5497 RPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTV 5556
RPPLN+NYVFTGY T N K +GEY F+K + + V YR TTTYKL+VGD F+LTSH V
Sbjct 5555 RPPLNKNYVFTGYHFTNNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFILTSHAV 5614
Query 5557 MPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSH 5614
LSAPTLVPQE+Y +R +Y ++ + F +NV NYQ +GM++Y T+QGPPGTGKSH
Sbjct 5615 SSLSAPTLVPQENYTSIRFASVY---SVPETFQNNVPNYQHIGMKRYCTVQGPPGTGKSH 5671
Query 5615 FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNS 5674
AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RV+C+DKFKVN
Sbjct 5672 LAIGLAVYYCTARVVYTAASHAAVDALCEKAHKFLNINDCTRIVPAKVRVDCYDKFKVND 5731
Query 5675 TLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRT 5734
T +YVF T+NALPE DI+V DE+SM TNY+LSV+N+R+RAKHYVYIGDPAQLPAPR
Sbjct 5732 TTRKYVFTTINALPELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGDPAQLPAPRV 5791
Query 5735 LLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ 5794
LL KGTLEP YFNSV +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA D S+
Sbjct 5792 LLNKGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYNNKLKAKNDNSSM 5851
Query 5795 CFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPT 5854
CFK++YKG TH+ SSA+N QI ++ +FL NP+W AVFISPYNSQN VA ++LGL T
Sbjct 5852 CFKVYYKGQTTHESSSAVNMQQIHLISKFLKANPSWSNAVFISPYNSQNYVAKRVLGLQT 5911
Query 5855 QTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSL 5914
QTVDS+QGSEYD+VI++QT ETAHS NVNRFNVAITRAK GILC+MS L++ L FT+L
Sbjct 5912 QTVDSAQGSEYDFVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSSMQLFESLNFTTL 5971
Query 5915 EIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKD 5973
+ + N LQ T LFKDCS+ G HP AP+ L+VD K+K G L V +
Sbjct 5972 TLDKINNPRLQC--TTNLFKDCSRSYVGYHPAHAPSFLAVDDKYKVGGDLAVCLNVADSA 6029
Query 5974 MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQ 6033
+TY RLIS+MGFK++ ++GY +FITR+EAI+ VRAW+GFD EG HA R+++GTN PLQ
Sbjct 6030 VTYSRLISLMGFKLDLTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHAIRDSIGTNFPLQ 6089
Query 6034 LGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQ 6093
LGFSTG++ V TG + F + +A+ PPG+QFKHLIPLM +G W+VVRI+IVQ
Sbjct 6090 LGFSTGIDFVVEATGMFAERDGYVFKKAAARAPPGEQFKHLIPLMSRGQKWDVVRIRIVQ 6149
Query 6094 MLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWH 6153
MLSD L +L+D VV V WA FELT ++YF K+G E C +C +RATCF++ + Y CW
Sbjct 6150 MLSDHLVDLADSVVLVTWAASFELTCLRYFAKVGREVVCSVCTKRATCFNSRTGYYGCWR 6209
Query 6154 HSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVK 6213
HS DY+YNP ++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+CF K
Sbjct 6210 HSYSCDYLYNPLIVDIQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRCLAVHDCFCK 6269
Query 6214 RVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEW 6273
V+W +EYPII +E+ +N +CR +Q ++ +AA+L +++ V +DIGNPK + CV D +
Sbjct 6270 SVNWNLEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKGYD--F 6327
Query 6274 KFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSN 6333
KFYDA P +++ Y Y H D+F DG+C+FWNCNVD+YPAN++VCRFDTRVL+
Sbjct 6328 KFYDASPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLNK 6384
Query 6334 LNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPL 6393
LNLPGC+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD+PC +DYVPL
Sbjct 6385 LNLPGCNGGSLYVNKHAFHTSPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPL 6444
Query 6394 KSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQS 6453
+SATCITRCNLGGAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFTRLQS
Sbjct 6445 RSATCITRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQS 6504
Query 6454 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 6513
LENV +N+VN GHFDG+ GE+P ++I V K+ DV +F+N T P NVA EL+AKR
Sbjct 6505 LENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAKR 6564
Query 6514 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 6573
+I+P PE+K+ NL +D+ + V+WDY +D+ ST VC TD+ L V
Sbjct 6565 SIRPHPELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVCKYTDL------QCIESLNV 6618
Query 6574 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEA-VKTQFNY 6630
FDGR +G ++ F+ RNGV I +K L GP++A LNGV + +G++ V+ F
Sbjct 6619 LFDGRDNGALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFAV 6678
Query 6631 YKKVDGVV-----------QQLPE--------------------TYFTQSRNLQEFKPRS 6659
K D V+ + P+ T FTQSR L F PRS
Sbjct 6679 RKDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRLLSSFTPRS 6738
Query 6660 QMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELED 6719
+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHLLIGLA+R ++S +++
Sbjct 6739 EMEKDFMDLDDDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRQQKSNLVIQE 6798
Query 6720 FIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEI 6779
F+ DS++ +YFITD +GSSK VC+VIDLLLDDFV+I+KS +L VSKVV V +D+ +
Sbjct 6799 FVTYDSSIHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKSLNLKCVSKVVNVNVDFKDF 6858
Query 6780 SFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIM 6839
FMLWC + V TFYP+LQ++ W+PG MP LYK LE+ +L NYG TLP G M
Sbjct 6859 QFMLWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPLERVNLWNYGKPITLPTGCM 6918
Query 6840 MNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLN 6899
MNVAKYTQLCQYL+T TLAVP NMRV+H GAGSDKGVAPG+AVLRQWLP G++LVD+D+N
Sbjct 6919 MNVAKYTQLCQYLSTTTLAVPANMRVLHLGAGSDKGVAPGSAVLRQWLPAGSILVDNDVN 6978
Query 6900 DFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKL 6959
FVSD+ ++ G+C T+ +WDLIISDMYDP TKN+ + N SK+GFFTY+C I+ KL
Sbjct 6979 PFVSDSVASYYGNCITLPFDCQWDLIISDMYDPLTKNIGEYNVSKDGFFTYLCHLIRDKL 7038
Query 6960 ALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDG 7019
ALGGSVAIKITE SWNA+LY LMG FA+WT F TNVNASSSE FLIG N+L K R +IDG
Sbjct 7039 ALGGSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWLNKTRTEIDG 7098
Query 7020 YVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLI 7079
MHANY+FWRN+ +YSLFDMSKFPLK GTAV+SLK QIND++LSL+ KG+L+
Sbjct 7099 KTMHANYLFWRNSTMWNGGAYSLFDMSKFPLKAAGTAVVSLKPDQINDLVLSLIEKGKLL 7158
Query 7080 IRENNRVVISSDVLVN 7095
+R+ + V D LVN
Sbjct 7159 VRDTRKEVFVGDSLVN 7174
Score = 79.0 bits (193), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 67/252 (27%), Positives = 118/252 (47%), Gaps = 20/252 (8%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV D+++ + V V+VN AN + HG GVAGA+ + +A E+ D +
Sbjct 1320 ITPNVCFVKGDVIKVVRLVNAEVIVNPANGRMAHGAGVAGAIAEKAGSAFIKETSDMVKA 1379
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENFNQHEVLLAPLLS 1150
G +VG +G L K L++VGP+ +G Q LL+ AY++ N+ + ++ L+S
Sbjct 1380 QGVCQVGECYESAGGKLCKKVLNIVGPDA-RGHGKQCYSLLERAYQHINKCDNVVTTLIS 1438
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + V NV L +++ +D + + K + ++A+
Sbjct 1439 AGIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFDVIEKCQVTSVAGTKALSLQLAKNLCR 1498
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+VK F+T + S+ ++C L+E + L ++ L ++ N +
Sbjct 1499 DVK-FVTNACSSLFS--------ESCFVSSYDVLQEVEALRHDIQLDDDARVFVQANMDC 1549
Query 1264 HPDSATLVSDID 1275
P LV+ D
Sbjct 1550 LPTDWRLVNKFD 1561
Score = 74.3 bits (181), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 108/457 (24%), Positives = 188/457 (41%), Gaps = 59/457 (13%)
Query 569 ILDGISQYSLRLIDA-MMFTSDLA------TNNLVVMAYITGGVVQLTSQWLTNIFGTVY 621
+LDG+ S LI + FTS + T+ + MA + V++ ++++ + G +
Sbjct 576 LLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMALLFMHDVKVATKYVKKVTGKLA 635
Query 622 EKLKPVLDWLEEKFKEGVEFLRD------GWEIVKFISTCACEIVGGQIVTCAKEIKESV 675
+ K + + K E + D GW + ++ V ++T +E+ E V
Sbjct 636 VRFKALGVAVVRKITEWFDLAVDIAASAAGWLCYQLVN--GLFAVANGVITFVQEVPELV 693
Query 676 QTFFKLVNKFLALCADSI---IIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMP 732
+ F F + DS+ I+ G + + SK +Y V + + +MP
Sbjct 694 KNFVDKFKAFFKVLIDSMSVSILSGLTVVKTASNRVCLAGSK-VYE--VVQKSLSAYVMP 750
Query 733 LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTPVCINGLML 790
+ E L GE P V + + ++ P + + P +CI +
Sbjct 751 VGC-SEATCLVGEIEPA-------VFEDDVVDVVKAPLTYQGCCKPPTSFEKICIVDKLY 802
Query 791 LEIKDTEKYCALAPN--MMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGYKSVNITFELDE 847
+ + Y + N + V + + A KV F D V ++ + + ITF LD
Sbjct 803 MAKCGDQFYPVVVDNDTVGVLDQCWRFPC-AGKKVEFNDKPKVRKIPSTRKIKITFALDA 861
Query 848 RIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPLGIDLDEWSMAT 904
D VL++ CS + V+ ++E VV DAV TL P E + T + LD +
Sbjct 862 TFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEHDVIGTKVCALLDRLAGDY 921
Query 905 YYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGA 964
YLFDE G+ +A MYCSF PD++ DC + + + + +DD A
Sbjct 922 VYLFDEGGDEVIAPRMYCSFSAPDDE----DCVAADVVDADENQ---DDD---------A 965
Query 965 TSAALQPEEEQEED-----WLDDDSQQTVGQQDGSED 996
+A+ + QEED ++ DS+ V E+
Sbjct 966 EDSAVLVADTQEEDGVAKGQVEADSEICVAHTGSQEE 1002
>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152
Score = 5341 bits (13856), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2744/5618 (49%), Positives = 3655/5618 (65%), Gaps = 175/5618 (3%)
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1620 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1679
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1680 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1738
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1739 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1798
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF+
Sbjct 1799 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPFL 1856
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ + G GHY H+ D + K + G +TD
Sbjct 1857 ICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLTD 1914
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--N 1922
Y +N + T T Y LD V +P L YY + Y+T +PI +P+ +
Sbjct 1915 CLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKVD 1973
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I LN G+ E KVT +P GDVV Y + K
Sbjct 1974 GVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2031
Query 1982 GAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNL 2039
G + KP++W H + N TY ++ ++ N + VL +D++
Sbjct 2032 GCETFGKPVIWLCHDEASLNSLTY----------FNKPSFKSENRYSVL------SVDSV 2075
Query 2040 ACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAA 2098
+ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2076 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2135
Query 2099 YVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTN 2155
Y+ + NELSR++ T+ +G+ + ++P D + N+ +
Sbjct 2136 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRDD---NQTLLVPKI 2191
Query 2156 IVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASF 2215
R + ++ + F + L FT T IA ++ L+ +F
Sbjct 2192 FKARAIEFY--GFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAF 2245
Query 2216 NYLKSPNFSKLINII-----IWF--LLLSVCLGSL---------IYSTAALGVLMSNLGM 2259
+ F K ++ WF L ++V I+ + + + G+
Sbjct 2246 QTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGL 2305
Query 2260 PSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISS---FKW 2316
+ C Y + + T + +C GS C +C SG D LDTY +++ +Q + F +
Sbjct 2306 VTICDFYSKLGVGFT----SHFCNGSFICELCYSGFDMLDTYAAIDFVQYEVDRRVLFDY 2361
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2362 -VSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2420
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2421 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2480
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2481 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2540
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + S + ++
Sbjct 2541 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVE--SDADRANF 2598
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2599 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVN 2658
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2659 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2718
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK+ NI+ IW + F L+ L+ +++ A
Sbjct 2719 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDTFNQLTADLQHKLKKAC 2778
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L ++L+ + + + P
Sbjct 2779 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPT 2835
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGS--YTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ GS Y N C
Sbjct 2836 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSFYYHNSMDC 2895
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2896 PIVVAVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2954
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2955 GCVLSSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 3014
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 3015 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQF 3074
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3075 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFL 3134
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3135 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3194
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N + STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3195 NHVLWLFS--YCRKIGVNVCNDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3250
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3251 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3310
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R + +F
Sbjct 3311 VSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDF 3370
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3371 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAF 3430
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3431 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYR 3490
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM + + D
Sbjct 3491 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADL 3550
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3551 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3607
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3608 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3666
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3667 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGLTYVWLSYFVPAVNFTYVYEVFYGCIL 3726
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3727 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3782
Query 3749 TTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3783 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3842
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3843 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKC 3902
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD- 3926
+VVLL+ LQ L V S+S+LW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3903 ANVVLLNCLQHLHVASNSRLWQYCSILHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDT 3962
Query 3927 -----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKL 3980
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L
Sbjct 3963 KCLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQL 4022
Query 3981 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4040
+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKL
Sbjct 4023 EKACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKL 4082
Query 4041 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQ 4100
DN ALN+I++NA GCVPLN IP A L ++IPD + D YA ++W IQ
Sbjct 4083 DNQALNSILDNAVKGCVPLNAIPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQT 4142
Query 4101 VVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGT 4158
V DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4143 VQDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGS 4198
Query 4159 TQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTD 4218
+ YYN GR V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4199 DMNC--NIPTQCYYNNGSSGRIVYAVLSDVDGLKYTKIIKDDGNCVV-LELDPPCKFSIQ 4255
Query 4219 TPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK 4278
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VD K
Sbjct 4256 DVKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKK 4315
Query 4279 AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPN 4338
Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+
Sbjct 4316 TYLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPD 4375
Query 4339 PKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQS 4398
G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D +
Sbjct 4376 VDGLCKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SGVAVQSKDL-N 4432
Query 4399 FLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNL 4457
FLNRV G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D+D N
Sbjct 4433 FLNRVRGTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRIDDDGNK 4492
Query 4458 IDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMA 4517
+D +FVVKR Y E+T Y L K C VA+HDFF F IDG VPHI R+ L+KYTM
Sbjct 4493 LDKFFVVKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRKNLSKYTML 4552
Query 4518 DLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQA 4577
DL YALRHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG +A
Sbjct 4553 DLCYALRHFDCNDCSVLCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGPIFNRA 4612
Query 4578 LLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPIL 4637
LL TV F D + G+VGVLTLDNQDL G WYDFGDFIQT PG GV V DSYYS +MP+L
Sbjct 4613 LLNTVSFADTLVKVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSYMMPML 4672
Query 4638 TLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDR 4697
T+ L E V+ Y ++DL++YDFT+ +L+LF++YFKYW YHPN V+C +DR
Sbjct 4673 TMCHVLDCELFVN----DSYRQFDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVDCDNDR 4728
Query 4698 CILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSR 4757
CI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H R
Sbjct 4729 CIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVDTHRYR 4788
Query 4758 LSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVS 4817
LS K+LL+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY+F S
Sbjct 4789 LSLKDLLLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFYEFVKS 4848
Query 4818 KGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDG 4877
KG FKEGS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDG
Sbjct 4849 KGLFKEGSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDG 4908
Query 4878 GCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLK 4937
GCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+TQMNLK
Sbjct 4909 GCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLTQMNLK 4968
Query 4938 YAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTV 4997
YAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ +
Sbjct 4969 YAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRHL 5028
Query 4998 YSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSE 5057
DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS RFYRLANECAQVLSE
Sbjct 5029 IKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECAQVLSE 5088
Query 5058 MVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQH 5117
+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +RNLQ
Sbjct 5089 IVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSIRNLQK 5148
Query 5118 RLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSV 5177
RLY +YR VD FVNE+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I F+ V
Sbjct 5149 RLYSNVYRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYASKGYIANISVFQQV 5208
Query 5178 LYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVD 5237
LYYQNNVFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGAGCFVD
Sbjct 5209 LYYQNNVFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGAGCFVD 5268
Query 5238 DIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSV 5297
D++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD YSV
Sbjct 5269 DLLKTDSVLLIERFVSLAIDAYPLVHHENEEYQKVFRVYLEYIKKLYNDLGNQILDSYSV 5328
Query 5298 MLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDH 5357
+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDH
Sbjct 5329 ILSTCDGLKFTDESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDH 5388
Query 5358 VISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLY 5417
V++T+HK VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG VFGLY
Sbjct 5389 VMATNHKYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGMVFGLY 5448
Query 5418 KNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIAT 5477
K +C GS + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK SY AT
Sbjct 5449 KQSCTGSPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQSYASAT 5508
Query 5478 VREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRG 5537
++E++SDRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + + V YR
Sbjct 5509 IQEIVSDREIILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNGVYYRA 5568
Query 5538 TTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLY--PTLNISDEFSSNVANY 5593
TTTYKL++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y P L F +NVANY
Sbjct 5569 TTTYKLSIGDVFVLTSHSVANLSAPTLVPQENYASIRFSSVYSVPLL-----FQTNVANY 5623
Query 5594 QKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDK 5653
Q +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+
Sbjct 5624 QHIGMKRYCTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLNIND 5683
Query 5654 CSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNA 5713
C+RIIPA+ RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NA
Sbjct 5684 CTRIIPAKVRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSVINA 5743
Query 5714 RLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIV 5773
R++AKHYVYIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP EIV
Sbjct 5744 RVKAKHYVYIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPKEIV 5803
Query 5774 DTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKA 5833
+TVSALVYDNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W A
Sbjct 5804 ETVSALVYDNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVWNSA 5863
Query 5834 VFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAK 5893
VFISPYNSQN VA +ILG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK
Sbjct 5864 VFISPYNSQNYVAKRILGVQTQTVDSAQGSEYDYVIYSQTAETAHSINVNRFNVAITRAK 5923
Query 5894 VGILCIMSDRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKVITGLHPTQAPTHL 5952
GI C+MS+ L++ L F +L + + TL + T LFKDCSK G HP AP+ L
Sbjct 5924 KGIFCVMSNMQLFESLNFITLPLDKIQNQTLSRLHCTTNLFKDCSKNFLGYHPAHAPSFL 5983
Query 5953 SVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAW 6011
SVD K+K E L V + +TY RLIS+MGFK++ ++GY FIT++EAI+ VR W
Sbjct 5984 SVDDKYKVNEDLAVCLNICEPVLTYSRLISLMGFKLDLTLDGYSKFFITKDEAIKRVRGW 6043
Query 6012 IGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQF 6071
+GFDVEG HATR+ +GTN PLQ+GFSTGV+ V TG + F R AK PPGD F
Sbjct 6044 VGFDVEGAHATRDNIGTNFPLQIGFSTGVDFVVEATGLFAERDCYIFKRTVAKAPPGDNF 6103
Query 6072 KHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERT 6131
KHLIPLM KG W+VVRI+IVQMLSD L +LSD VVF+ W+ FELT ++YF K+G E
Sbjct 6104 KHLIPLMSKGQKWDVVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGRELN 6163
Query 6132 CCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGN 6191
C +C RATC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD+ C VH
Sbjct 6164 CDVCPNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNVHKG 6223
Query 6192 AHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKF 6251
AHVAS DAIMTRCLA+++CF K V+W +EYPII +E+ IN +CR +Q +++KAA+L +++
Sbjct 6224 AHVASSDAIMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLCNRY 6283
Query 6252 PVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWN 6311
+ +DIGNPK I CV D E+KFYDA P +++LFY Y H D F DG+C+FWN
Sbjct 6284 NLCYDIGNPKGIACVK--DYEFKFYDASPV---VKSVKQLFYVYDVHKDNFKDGLCMFWN 6338
Query 6312 CNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFY 6371
CNVD+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +PFFY
Sbjct 6339 CNVDKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMPFFY 6398
Query 6372 YSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGF 6431
YSD+PC +DYVPL+SATCITRCNLGGAVC HA +Y YL++YN+ +AGF
Sbjct 6399 YSDTPCVYVDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEDYCKYLESYNVATTAGF 6458
Query 6432 SLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVD 6491
+ WVYK FD YNLWNTFT LQSLENV +N+VN GH+DG+ GE+P +I+N+ V K++ VD
Sbjct 6459 TFWVYKTFDFYNLWNTFTMLQSLENVIYNLVNAGHYDGRIGELPCAIMNDKVVVKINNVD 6518
Query 6492 VELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTI 6551
+F+N T+LP N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +D+ ST
Sbjct 6519 TVIFKNNTSLPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTY 6578
Query 6552 GVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQ 6611
GVC TD+ L V FDGR +G ++ FR ARNGV I+ G + L GP++
Sbjct 6579 GVCKYTDL------NFIENLNVLFDGRDNGALEAFRKARNGVFISTGKLSSLSMIKGPQR 6632
Query 6612 ASLNGVTL--IGEA-VKTQFNYYKKVDGVVQQLPE------------------------- 6643
A LNGV + +GE V+ F K D V+ +
Sbjct 6633 ADLNGVIVDKVGELNVEFWFAMRKDGDDVIFSRADSLSPSHYWSPQGNLGGNCAGNASGN 6692
Query 6644 ------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQL 6697
T FTQSR L F+PRS +E DF+++ FI +Y LE YAF+HIVYG F++ +
Sbjct 6693 DALARFTIFTQSRVLSTFEPRSDLERDFIDMEDSLFIAKYGLEDYAFDHIVYGSFNYKVI 6752
Query 6698 GGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEI 6757
GGLHLLIGL +R K+S +++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I
Sbjct 6753 GGLHLLIGLFRRLKKSNLVIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVVI 6812
Query 6758 IKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQR 6817
+KS +L+ VSKVV + +D+ + FMLWC D + TFYPK+Q++ W+PG +MP LYK
Sbjct 6813 VKSLNLNCVSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATSDWKPGYSMPVLYKYLN 6872
Query 6818 MLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVA 6877
+ LE+ L NYG + LP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VA
Sbjct 6873 VPLERVSLWNYGKAINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSDKEVA 6932
Query 6878 PGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNV 6937
PG+AVLRQWLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP TKN+
Sbjct 6933 PGSAVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPLTKNI 6992
Query 6938 TKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNA 6997
N SK+GFFTYIC I+ KL+LGGSVAIKITE SWNADLYKLM +FA+WT F TNVNA
Sbjct 6993 GDYNVSKDGFFTYICYLIRDKLSLGGSVAIKITEFSWNADLYKLMSYFAFWTVFCTNVNA 7052
Query 6998 SSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAV 7057
SSSE FLIG NYLGK +IDG VMHANY+FWRN+ +YSLFDMSKF LKL GTAV
Sbjct 7053 SSSEGFLIGINYLGKSCFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMSKFSLKLAGTAV 7112
Query 7058 MSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
++L+ Q+ND++ SL+ +G+L++R+ + + D LVN
Sbjct 7113 VNLRPDQLNDLVYSLIERGKLLVRDTRKEIFVGDSLVN 7150
Score = 81.6 bits (200), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 53/155 (34%), Positives = 79/155 (51%), Gaps = 2/155 (1%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A E+ +
Sbjct 1328 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1387
Query 1092 ATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHEVLLAPLL 1149
+ G +VG V +G L K L++VGP+ + + LL AY++ N ++ L+ L+
Sbjct 1388 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1447
Query 1150 SAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
SAGIF SL + V V L +K +D
Sbjct 1448 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFD 1482
Score = 73.6 bits (179), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 102/422 (24%), Positives = 172/422 (41%), Gaps = 63/422 (15%)
Query 562 LQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW-------- 612
L ++ I +SQ+S + D + L + + V YI V +L +Q+
Sbjct 562 LIQSGIFFTSLMSQFSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLV 621
Query 613 --LTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKE 670
+ N F T+ + P WL + G+ F+ + A I AK
Sbjct 622 NKMVNWFNTMLDASAPATGWLLYQLLNGL-----------FVVSQANFNFVALIPDYAKI 670
Query 671 IKESVQTFFKLVNKFLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSRE 725
+ TFFKL+ L ++ LK +N +G F S GL
Sbjct 671 LVNKFYTFFKLL---LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI-------- 719
Query 726 ETGLLMPLKA-PKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTP 782
G ++P A ++I F EG + E V+++ ++ ++ S E + P
Sbjct 720 -PGFVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEK 771
Query 783 VCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGG-----APTKVTFGDDTVI-EVQGY 836
+CI M + K +K+ P +M N L A KV F + V+ E+
Sbjct 772 ICIIDNMYMG-KCGDKF---FPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 837 KSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPL 893
+V + F+LD D +L + CS + VE G V++F VV DA+ L + + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKDHPVVGYQV 887
Query 894 GIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTE 952
L++ + YLFDE+G+ +AS MYC+F D ED + E+ + + +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 953 DD 954
+D
Sbjct 948 ED 949
Score = 44.3 bits (103), Expect = 0.060, Method: Compositional matrix adjust.
Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 16/148 (11%)
Query 1658 YPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAY 1717
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1115 YFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTT 1174
Query 1718 CNKTV--GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
K + + G V + + ++++ N C CG L G++AV + G +
Sbjct 1175 IPKAIVLPQGGYVADFAYWFLNQFDINA---YANWCCLKCG-FSFDLNGLDAVFFYGDI- 1229
Query 1776 YEQFKKGVQIPCTCGKQATKYLVQQESP 1803
V C CG T L+ + P
Sbjct 1230 -------VSHVCKCGHNMT--LIAADLP 1248
>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132
Score = 5340 bits (13853), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2744/5622 (49%), Positives = 3662/5622 (65%), Gaps = 183/5622 (3%)
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1600 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1659
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1660 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1718
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1719 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1778
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF+
Sbjct 1779 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPFL 1836
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ + G GHY H+ D + K + G +TD
Sbjct 1837 ICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLTD 1894
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--N 1922
Y +N + T T Y LD V +P L YY + Y+T +PI +P+ +
Sbjct 1895 CLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKVD 1953
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I LN G+ E KVT +P GDVV Y + K
Sbjct 1954 GVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2011
Query 1982 GAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNL 2039
G + KP++W H + N TY ++ ++ N + VL +D++
Sbjct 2012 GCETFGKPVIWFCHDEASLNSLTY----------FNKPSFKSENRYSVL------SVDSV 2055
Query 2040 ACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAA 2098
+ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2056 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2115
Query 2099 YVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTN 2155
Y+ + NELSR++ T+ +G+ + ++P D + N+ +
Sbjct 2116 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRDD---NQTLLVPKI 2171
Query 2156 IVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASF 2215
R + ++ + F + L FT T IA ++ L+ +F
Sbjct 2172 FKARAIEFY--GFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAF 2225
Query 2216 NYLKSPNFSKLINII-----IWF--LLLSVCLGSL---------IYSTAALGVLMSNLGM 2259
+ F K ++ WF L ++V I+ + + + G+
Sbjct 2226 QTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGL 2285
Query 2260 PSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISS---FKW 2316
+ C Y + + T + +C GS C +C SG D LDTY +++ +Q + F +
Sbjct 2286 VTICDFYSKLGVGFT----SHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDY 2341
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2342 -VSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2400
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2401 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2460
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2461 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2520
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + S + ++
Sbjct 2521 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVE--SDADRANF 2578
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2579 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQIMFDVYVDTFMSHFDVDRKSFNNFVN 2638
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2639 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2698
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK NI+ IW + F L+ L+ +++ A
Sbjct 2699 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKVANISCIWFIDAFNQLTADLQHKLKKAC 2758
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L ++L+ + + + P
Sbjct 2759 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPT 2815
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGS--YTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ GS Y N C
Sbjct 2816 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDC 2875
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2876 PIVVAVMDEDIGSTMFNVPTKVLRY-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2934
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2935 GCVLSSLCTMFKRGDGTPHPYCYTDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 2994
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 2995 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDFFDLFYQF 3054
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3055 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFL 3114
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3115 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3174
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N S STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3175 NHVLWLFS--YCRKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3230
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3231 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3290
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R + +F
Sbjct 3291 VSPTSKIEPCLVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDF 3350
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3351 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAF 3410
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3411 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFNGNFYGPYR 3470
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM + + D
Sbjct 3471 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADL 3530
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3531 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3587
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3588 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3646
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3647 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYEVFYGCIL 3706
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3707 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3762
Query 3749 TTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3763 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3822
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3823 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKC 3882
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD- 3926
+VVLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL S AVD
Sbjct 3883 ANVVLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFSNPAAVDT 3942
Query 3927 -----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKL 3980
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L
Sbjct 3943 KCLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQL 4002
Query 3981 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4040
+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKL
Sbjct 4003 EKACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKL 4062
Query 4041 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQ 4100
DN ALN+I++NA GCVPL+ IP A L ++IPD + D TYA ++W IQ
Sbjct 4063 DNQALNSILDNAVKGCVPLSAIPALAANTLTIIIPDKQVFDKVVDNVYVTYAGSVWHIQT 4122
Query 4101 VVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGT 4158
V DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4123 VQDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGS 4178
Query 4159 -----TQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPC 4213
T C YYN GR V A+LSD+ LK+ + K DG + EL+PPC
Sbjct 4179 DINCNIPTQC-------YYNNVSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPC 4230
Query 4214 RFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFA 4273
+F KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+
Sbjct 4231 KFSIQDVKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFS 4290
Query 4274 VDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCH 4333
VD K Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR
Sbjct 4291 VDPKKTYLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRAR 4350
Query 4334 IDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQS 4393
++HP+ G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS
Sbjct 4351 VEHPDVDGICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SSVAVQS 4408
Query 4394 ADAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKD 4452
D +FLNRV G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D
Sbjct 4409 KDL-NFLNRVRGTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRID 4467
Query 4453 EDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLT 4512
+D N +D +FVVKR Y E+T Y L K C VA+HDFF F IDG VPHI R+ L+
Sbjct 4468 DDGNKLDKFFVVKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRRNLS 4527
Query 4513 KYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGE 4572
KYTM DL YALRHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG
Sbjct 4528 KYTMLDLCYALRHFDRNDCSILCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGP 4587
Query 4573 RVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSL 4632
+ALL TV F D + G+VGVLTLDNQDL G WYDFGDFIQT PG GV V DSYYS
Sbjct 4588 IFNRALLNTVIFADTLVEVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSY 4647
Query 4633 LMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVN 4692
+MP+LT+ L E V+ Y ++DL++YDFT+ +L+LF++YFKYW YHPN V+
Sbjct 4648 MMPMLTMCHVLDCELFVN----DSYRQFDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVD 4703
Query 4693 CLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVN 4752
C +DRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+
Sbjct 4704 CDNDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVD 4763
Query 4753 LHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFY 4812
H RLS K+LL+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY
Sbjct 4764 THRYRLSLKDLLLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFY 4823
Query 4813 DFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF 4872
+F SKG FKEGS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF
Sbjct 4824 EFVKSKGLFKEGSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYF 4883
Query 4873 DCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTIT 4932
+ YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+T
Sbjct 4884 EIYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLT 4943
Query 4933 QMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHN 4992
QMNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +
Sbjct 4944 QMNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDD 5003
Query 4993 MLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECA 5052
ML+ + DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS RFYRLANECA
Sbjct 5004 MLRHLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECA 5063
Query 5053 QVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYV 5112
QVLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +
Sbjct 5064 QVLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSI 5123
Query 5113 RNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIK 5172
RNLQ RLY +YR VD FVNE+Y +L KHFSMMILSDD VVC+NS YA++G +A+I
Sbjct 5124 RNLQKRLYSNVYRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYANKGYIANIS 5183
Query 5173 NFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGA 5232
F+ VLYYQNNVFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGA
Sbjct 5184 AFQQVLYYQNNVFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGA 5243
Query 5233 GCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHML 5292
GCFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +L
Sbjct 5244 GCFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNDLGTQIL 5303
Query 5293 DMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCK 5352
D YSV+L+ + ++ E FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCK
Sbjct 5304 DSYSVILSTCDGLKFTEESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCK 5363
Query 5353 CCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQ 5412
CCYDHV++T+HK VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG
Sbjct 5364 CCYDHVMATNHKYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGM 5423
Query 5413 VFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLS 5472
VFGLYK +C GS + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK S
Sbjct 5424 VFGLYKQSCTGSPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQS 5483
Query 5473 YGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDA 5532
Y AT++E++SDRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + +
Sbjct 5484 YASATIQEIVSDREVILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNG 5543
Query 5533 VVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNV 5590
V YR TTTYKL++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y ++ F +NV
Sbjct 5544 VYYRATTTYKLSIGDVFVLTSHSVASLSAPTLVPQENYASIRFSSVY---SVPLVFQNNV 5600
Query 5591 ANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLP 5650
ANYQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L
Sbjct 5601 ANYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLN 5660
Query 5651 IDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSV 5710
I+ C+RIIPA+ RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV
Sbjct 5661 INDCTRIIPAKVRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSV 5720
Query 5711 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5770
+NAR++AKHYVYIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP
Sbjct 5721 INARIKAKHYVYIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPK 5780
Query 5771 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5830
EIV+TVSALVYDNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W
Sbjct 5781 EIVETVSALVYDNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVW 5840
Query 5831 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAIT 5890
AVFISPYNSQN VA ++LG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAIT
Sbjct 5841 NSAVFISPYNSQNYVAKRVLGVQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAIT 5900
Query 5891 RAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKVITGLHPTQAP 5949
RAK GI C+MS+ L++ L F +L + + TL + T LFKDCSK G HP AP
Sbjct 5901 RAKKGIFCVMSNMQLFESLNFITLPLDKIQNQTLPRLHCTTNLFKDCSKSCLGYHPAHAP 5960
Query 5950 THLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHV 6008
+ L+VD K+K E L V++ +TY RLIS+MGFK++ ++GY +FIT++EAI+ V
Sbjct 5961 SFLAVDDKYKVNENLAVNLNICEPVLTYSRLISLMGFKLDLTLDGYSKLFITKDEAIKRV 6020
Query 6009 RAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPG 6068
R W+GFDVEG HATRE +GTN PLQ+GFSTGV+ V TG + F + AK PPG
Sbjct 6021 RGWVGFDVEGAHATRENIGTNFPLQIGFSTGVDFVVEATGLFAERDCYTFKKTVAKAPPG 6080
Query 6069 DQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGP 6128
++FKHLIPLM KG W++VRI+IVQMLSD L +LSD VVF+ W+ FELT ++YF K+G
Sbjct 6081 EKFKHLIPLMSKGQKWDIVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGR 6140
Query 6129 ERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQV 6188
E C +C RATC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD+ C V
Sbjct 6141 ELNCNVCSNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNV 6200
Query 6189 HGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLA 6248
H AHVAS DAIMTRCLA+++CF K V+W +EYPII +E+ IN +CR +Q +++KAA+L
Sbjct 6201 HKGAHVASADAIMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLC 6260
Query 6249 DKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCL 6308
+++ + +DIGNPK + CV D E+KFYDA P A +++LFY Y H D F DG+C+
Sbjct 6261 NRYNLCYDIGNPKGLACVK--DYEFKFYDAFPV---AKSVKQLFYVYDVHKDNFKDGLCM 6315
Query 6309 FWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLP 6368
FWNCNVD+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +P
Sbjct 6316 FWNCNVDKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMP 6375
Query 6369 FFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMIS 6428
FFYYSD+PC +DYVPL+SATCITRCNLGGAVC HA EY YL++YN++ +
Sbjct 6376 FFYYSDTPCVYVDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEEYCNYLESYNIVTT 6435
Query 6429 AGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVD 6488
AGF+ WVYK FD YNLWNTFT LQSLENV +N+VN GH+DG+ GE+P +I+N+ V K++
Sbjct 6436 AGFTFWVYKTFDFYNLWNTFTTLQSLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKIN 6495
Query 6489 GVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHI 6548
VD +F+N T+ P N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +D+
Sbjct 6496 NVDTVIFKNNTSFPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCS 6555
Query 6549 STIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVG 6608
ST GVC TD+ K E L + FDGR G ++ FR ARNGV I+ + L G
Sbjct 6556 STYGVCKYTDL--KFIEN----LNILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKG 6609
Query 6609 PKQASLNGVTL--IGEAVKTQFNYYKKVDG--VVQQLPE--------------------- 6643
P++A LNGV + +GE +K +F + + DG V+ +
Sbjct 6610 PQRADLNGVIVDKVGE-LKVEFWFAMRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGN 6668
Query 6644 ----------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFS 6693
T FTQSR L F+PRS +E DF+++ + FI +Y LE YAF+HIVYG F+
Sbjct 6669 VIGNDALTRFTIFTQSRVLSSFEPRSDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFN 6728
Query 6694 HSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDD 6753
H +GGLHLLIGL +R K+S +++F+ DS++ +YFITD + GSSK VC+VIDLLLDD
Sbjct 6729 HKVIGGLHLLIGLFRRLKKSNLLIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDD 6788
Query 6754 FVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLY 6813
FV I+KS +LS VSKVV + +D+ + FMLWC D + TFYPK+Q++ W+PG +MP LY
Sbjct 6789 FVSIVKSLNLSCVSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATNDWKPGYSMPVLY 6848
Query 6814 KMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSD 6873
K + LE+ L NYG LP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSD
Sbjct 6849 KYLNVPLERVSLWNYGKPINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSD 6908
Query 6874 KGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPK 6933
K VAPG+AVLRQWLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP
Sbjct 6909 KEVAPGSAVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPL 6968
Query 6934 TKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVT 6993
TKN+ N SK+GFFTYIC I+ KL+LGGSVAIKITE SWNADLYKLM FA+WT F T
Sbjct 6969 TKNIGDYNVSKDGFFTYICHLIRDKLSLGGSVAIKITEFSWNADLYKLMSCFAFWTVFCT 7028
Query 6994 NVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLR 7053
NVNASSSE FLIG NYLGK +IDG VMHANY+FWRN+ +YSLFDM+KF LKL
Sbjct 7029 NVNASSSEGFLIGINYLGKSSFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMTKFSLKLA 7088
Query 7054 GTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
GTAV++L+ Q+ND++ SL+ +G+L++R+ + + D LVN
Sbjct 7089 GTAVVNLRPDQLNDLVYSLIERGKLLVRDTRKEIFVGDSLVN 7130
Score = 82.0 bits (201), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 53/155 (34%), Positives = 79/155 (51%), Gaps = 2/155 (1%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A E+ +
Sbjct 1308 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1367
Query 1092 ATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHEVLLAPLL 1149
+ G +VG V +G L K L++VGP+ + + LL AY++ N ++ L+ L+
Sbjct 1368 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1427
Query 1150 SAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
SAGIF SL + V V L +K +D
Sbjct 1428 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFD 1462
Score = 74.3 bits (181), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 103/422 (24%), Positives = 171/422 (41%), Gaps = 63/422 (15%)
Query 562 LQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW-------- 612
L ++ I +SQ+S + D + L + + V YI V +L +Q+
Sbjct 562 LIQSGIFFTSLMSQFSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLV 621
Query 613 --LTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKE 670
+ N F T+ + P WL + G F+ + A I AK
Sbjct 622 NKMVNWFNTMLDASAPATGWLLYQLLNGF-----------FVVSQANLNFVALIPDYAKI 670
Query 671 IKESVQTFFKLVNKFLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSRE 725
+ TFFKL+ L ++ LK +N +G F S GL
Sbjct 671 LVNKFYTFFKLL---LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI-------- 719
Query 726 ETGLLMPLKA-PKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTP 782
G ++P A ++I F EG + E V+++ ++ ++ S E + P
Sbjct 720 -PGFVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEK 771
Query 783 VCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGG-----APTKVTFGDDTVI-EVQGY 836
+CI M + K +K+ P +M N L A KV F + V+ E+
Sbjct 772 ICIIDNMYMG-KCGDKF---FPIVMNDKNICLLDHAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 837 KSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPL 893
+V + F+LD D +L + CS + VE G V++F VV DA+ L E + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQV 887
Query 894 GIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTE 952
L++ + YLFDE+G+ +AS MYC+F D ED + E+ + + +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 953 DD 954
+D
Sbjct 948 ED 949
Score = 44.3 bits (103), Expect = 0.063, Method: Compositional matrix adjust.
Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 16/148 (11%)
Query 1658 YPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAY 1717
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1095 YFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTT 1154
Query 1718 CNKTV--GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
K + + G V + + ++++ N C CG L G++AV + G +
Sbjct 1155 IPKAIVLPQGGYVADFAYWFLNQFDINA---YANWCCLKCG-FSFDLNGLDAVFFYGDI- 1209
Query 1776 YEQFKKGVQIPCTCGKQATKYLVQQESP 1803
V C CG T L+ + P
Sbjct 1210 -------VSHVCKCGHNMT--LIAADLP 1228
>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182
Score = 5337 bits (13845), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2744/5617 (49%), Positives = 3662/5617 (65%), Gaps = 173/5617 (3%)
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1650 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1709
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1710 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1768
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1769 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1828
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF+
Sbjct 1829 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPFL 1886
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ + G GHY H+ D + K + G +TD
Sbjct 1887 ICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLTD 1944
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--N 1922
Y +N + T T Y LD V +P L YY + Y+T +PI +P+ +
Sbjct 1945 CLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKVD 2003
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I LN G+ E KVT +P GDVV Y + K
Sbjct 2004 GVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2061
Query 1982 GAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNL 2039
G + KP++W H + N TY ++ ++ N + VL +D++
Sbjct 2062 GCETFGKPVIWFCHDEASLNSLTY----------FNKPSFKSENRYSVL------SVDSV 2105
Query 2040 ACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAA 2098
+ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2106 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2165
Query 2099 YVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTN 2155
Y+ + NELSR++ T+ +G+ + ++P D + N+ +
Sbjct 2166 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRDD---NQTLLVPKI 2221
Query 2156 IVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASF 2215
R + ++ + F + L FT T IA ++ L+ +F
Sbjct 2222 FKARAIEFY--GFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAF 2275
Query 2216 NYLKSPNFSKLINII-----IWF--LLLSVCLGSL---------IYSTAALGVLMSNLGM 2259
+ F K ++ WF L ++V I+ + + + G+
Sbjct 2276 QTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGL 2335
Query 2260 PSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISS---FKW 2316
+ C Y + + T + +C GS C +C SG D LDTY +++ +Q + F +
Sbjct 2336 VTICDFYSKLGVGFT----SHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDY 2391
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2392 -VSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2450
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2451 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2510
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2511 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2570
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + S + ++
Sbjct 2571 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVE--SDADRANF 2628
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2629 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVN 2688
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2689 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2748
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK+ NI+ IW + F L+ L+ +++ A
Sbjct 2749 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDAFNQLTADLQHKLKKAC 2808
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L V+L+ + + + P
Sbjct 2809 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFVSLICFI---LLWALLPT 2865
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGS--YTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ GS Y N C
Sbjct 2866 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDC 2925
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2926 PIVVAVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2984
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2985 GCVLSSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 3044
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 3045 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQF 3104
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3105 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVVVWCINFL 3164
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3165 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3224
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N S STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3225 NHVLWLFS--YCRKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3280
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3281 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3340
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC+S +M P+Y LL R + +F
Sbjct 3341 VSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICSSSNMNEPDYSALLCRVTLGDF 3400
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3401 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGNVKPGETFTVLAAYNGRPQGAF 3460
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3461 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYR 3520
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ + DFN+ AM + + D
Sbjct 3521 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSTEDFNVWAMANGFSQVKADL 3580
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3581 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3637
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3638 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3696
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3697 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSYFVPAVNFTYVYEVFYGCIL 3756
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3757 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3812
Query 3749 TTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3813 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3872
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3873 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKC 3932
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD- 3926
+VVLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3933 ANVVLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDT 3992
Query 3927 -----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKL 3980
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L
Sbjct 3993 KCLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQL 4052
Query 3981 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4040
+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKL
Sbjct 4053 EKACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKL 4112
Query 4041 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQ 4100
DN ALN+I++NA GCVPL+ IP A L +VIPD + D TYA ++W IQ
Sbjct 4113 DNQALNSILDNAVKGCVPLSAIPALAANTLTIVIPDKQVFDKVVDNVYVTYAGSVWHIQT 4172
Query 4101 VVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGT 4158
V DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4173 VQDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGS 4228
Query 4159 TQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTD 4218
+ YYN GR V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4229 DMNC--NIPTQCYYNNGSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFSIQ 4285
Query 4219 TPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK 4278
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VD K
Sbjct 4286 DVKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKK 4345
Query 4279 AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPN 4338
Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+
Sbjct 4346 TYLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPD 4405
Query 4339 PKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQS 4398
G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D +
Sbjct 4406 VDGICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SSVAVQSKDL-N 4462
Query 4399 FLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNL 4457
FLNRV G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D+D N
Sbjct 4463 FLNRVRGTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRIDDDGNK 4522
Query 4458 IDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMA 4517
+D +FVVKR Y E+T Y L K C VA+HDFF F IDG VPHI R+ L+KYTM
Sbjct 4523 LDKFFVVKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRRNLSKYTML 4582
Query 4518 DLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQA 4577
DL YALRHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG +A
Sbjct 4583 DLCYALRHFDRNDCSILCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGPIFNRA 4642
Query 4578 LLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPIL 4637
LL TV F D + G+VGVLTLDNQDL G WYDFGDFIQT PG GV V DSYYS +MP+L
Sbjct 4643 LLNTVIFADTLVEVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSYMMPML 4702
Query 4638 TLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDR 4697
T+ L E V+ Y ++DL++YDFT+ +L+LF++YFKYW YHPN V+C +DR
Sbjct 4703 TMCHVLDCELFVN----DSYRQFDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVDCDNDR 4758
Query 4698 CILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSR 4757
CI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H R
Sbjct 4759 CIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVDTHRYR 4818
Query 4758 LSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVS 4817
LS K+LL+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY+F S
Sbjct 4819 LSLKDLLLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFYEFVKS 4878
Query 4818 KGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDG 4877
KG FKEGS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDG
Sbjct 4879 KGLFKEGSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDG 4938
Query 4878 GCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLK 4937
GCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+TQMNLK
Sbjct 4939 GCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLTQMNLK 4998
Query 4938 YAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTV 4997
YAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ +
Sbjct 4999 YAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRHL 5058
Query 4998 YSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSE 5057
DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS RFYRLANECAQVLSE
Sbjct 5059 IKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECAQVLSE 5118
Query 5058 MVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQH 5117
+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +RNLQ
Sbjct 5119 IVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSIRNLQK 5178
Query 5118 RLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSV 5177
RLY +YR VD FVNE+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I F+ V
Sbjct 5179 RLYSNVYRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYASKGYIANISVFQQV 5238
Query 5178 LYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVD 5237
LYYQNNVFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGAGCFVD
Sbjct 5239 LYYQNNVFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGAGCFVD 5298
Query 5238 DIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSV 5297
D++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD YSV
Sbjct 5299 DLLKTDSVLLIERFVSLAIDAYPLVHHENEEYQKVFRVYLEYIKKLYNDLGTQILDSYSV 5358
Query 5298 MLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDH 5357
+L+ + ++ E FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDH
Sbjct 5359 ILSTCDGLKFTEESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDH 5418
Query 5358 VISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLY 5417
V++T+HK VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG VFGLY
Sbjct 5419 VMATNHKYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGMVFGLY 5478
Query 5418 KNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIAT 5477
K +C GS + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK SY AT
Sbjct 5479 KQSCTGSPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQSYASAT 5538
Query 5478 VREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRG 5537
++E++SDRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + + V YR
Sbjct 5539 IQEIVSDREVILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNGVYYRA 5598
Query 5538 TTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQK 5595
TTTYKL++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y ++ F +NVANYQ
Sbjct 5599 TTTYKLSIGDVFVLTSHSVASLSAPTLVPQENYASIRFSSVY---SVPLVFQNNVANYQH 5655
Query 5596 VGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS 5655
+GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+
Sbjct 5656 IGMKRYCTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLNINDCT 5715
Query 5656 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5715
RIIPA+ RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NAR+
Sbjct 5716 RIIPAKVRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSVINARI 5775
Query 5716 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5775
+AKHYVYIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP EIV+T
Sbjct 5776 KAKHYVYIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPKEIVET 5835
Query 5776 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVF 5835
VSALVYDNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W AVF
Sbjct 5836 VSALVYDNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVWNSAVF 5895
Query 5836 ISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVG 5895
ISPYNSQN VA ++LG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK G
Sbjct 5896 ISPYNSQNYVAKRVLGVQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKG 5955
Query 5896 ILCIMSDRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKVITGLHPTQAPTHLSV 5954
I C+MS+ L++ L F +L + + TL + T LFKDCSK G HP AP+ L+V
Sbjct 5956 IFCVMSNMQLFESLNFITLPLDKIQNQTLPRLHCTTNLFKDCSKSCLGYHPAHAPSFLAV 6015
Query 5955 DTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIG 6013
D K+K E L V++ +TY RLIS+MGFK++ ++GY +FIT++EAI+ VR W+G
Sbjct 6016 DDKYKVNENLAVNLNICEPVLTYSRLISLMGFKLDLTLDGYSKLFITKDEAIKRVRGWVG 6075
Query 6014 FDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKH 6073
FDVEG HATRE +GTN PLQ+GFSTGV+ V TG + F + AK PPG++FKH
Sbjct 6076 FDVEGAHATRENIGTNFPLQIGFSTGVDFVVEATGLFAERDCYTFKKTVAKAPPGEKFKH 6135
Query 6074 LIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCC 6133
LIPLM KG W++VRI+IVQMLSD L +LSD VVF+ W+ FELT ++YF K+G E C
Sbjct 6136 LIPLMSKGQKWDIVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGRELNCN 6195
Query 6134 LCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAH 6193
+C RATC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD+ C VH AH
Sbjct 6196 VCSNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNVHKGAH 6255
Query 6194 VASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPV 6253
VAS DAIMTRCLA+++CF K V+W +EYPII +E+ IN +CR +Q +++KAA+L +++ +
Sbjct 6256 VASADAIMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLCNRYNL 6315
Query 6254 LHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCN 6313
+DIGNPK + CV D E+KFYDA P A +++LFY Y H D F DG+C+FWNCN
Sbjct 6316 CYDIGNPKGLACVK--DYEFKFYDAFPV---AKSVKQLFYVYDVHKDNFKDGLCMFWNCN 6370
Query 6314 VDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYS 6373
VD+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +PFFYYS
Sbjct 6371 VDKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMPFFYYS 6430
Query 6374 DSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSL 6433
D+PC +DYVPL+SATCITRCNLGGAVC HA EY YL++YN++ +AGF+
Sbjct 6431 DTPCVYVDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEEYCNYLESYNIVTTAGFTF 6490
Query 6434 WVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVE 6493
WVYK FD YNLWNTFT LQSLENV +N+VN GH+DG+ GE+P +I+N+ V K++ VD
Sbjct 6491 WVYKNFDFYNLWNTFTTLQSLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKINNVDTV 6550
Query 6494 LFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGV 6553
+F+N T+ P N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +D+ ST GV
Sbjct 6551 IFKNNTSFPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGV 6610
Query 6554 CSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQAS 6613
C TD+ K E L + FDGR G ++ FR ARNGV I+ + L GP++A
Sbjct 6611 CKYTDL--KFIEN----LNILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKGPQRAD 6664
Query 6614 LNGVTL--IGEAVKTQFNYYKKVDG--VVQQLPE-------------------------- 6643
LNGV + +GE +K +F + + DG V+ +
Sbjct 6665 LNGVIVDKVGE-LKVEFWFAMRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGNVIGND 6723
Query 6644 -----TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLG 6698
T FTQSR L F+PRS +E DF+++ + FI +Y LE YAF+HIVYG F+H +G
Sbjct 6724 ALTRFTIFTQSRVLSSFEPRSDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFNHKVIG 6783
Query 6699 GLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEII 6758
GLHLLIGL +R K+S +++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+
Sbjct 6784 GLHLLIGLFRRKKKSNLLIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVSIV 6843
Query 6759 KSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRM 6818
KS +LS VSKVV + +D+ + FMLWC D + TFYPK+Q++ W+PG +MP LYK +
Sbjct 6844 KSLNLSCVSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATNDWKPGYSMPVLYKYLNV 6903
Query 6819 LLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAP 6878
LE+ L NYG LP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAP
Sbjct 6904 PLERVSLWNYGKPINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSDKEVAP 6963
Query 6879 GTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVT 6938
G+AVLRQWLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP TKN+
Sbjct 6964 GSAVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPLTKNIG 7023
Query 6939 KENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNAS 6998
N SK+GFFTYIC I+ KL+LGGSVAIKITE SWNADLYKLM FA+WT F TNVNAS
Sbjct 7024 DYNVSKDGFFTYICHLIRDKLSLGGSVAIKITEFSWNADLYKLMSCFAFWTVFCTNVNAS 7083
Query 6999 SSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVM 7058
SSE FLIG NYLGK +IDG VMHANY+FWRN+ +YSLFDM+KF LKL GTAV+
Sbjct 7084 SSEGFLIGINYLGKSSFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMTKFSLKLAGTAVV 7143
Query 7059 SLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
+L+ Q+ND++ SL+ +G+L++R+ + + D LVN
Sbjct 7144 NLRPDQLNDLVYSLIERGKLLVRDTRKEIFVGDSLVN 7180
Score = 81.6 bits (200), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 53/155 (34%), Positives = 79/155 (51%), Gaps = 2/155 (1%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A E+ +
Sbjct 1358 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1417
Query 1092 ATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHEVLLAPLL 1149
+ G +VG V +G L K L++VGP+ + + LL AY++ N ++ L+ L+
Sbjct 1418 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1477
Query 1150 SAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
SAGIF SL + V V L +K +D
Sbjct 1478 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFD 1512
Score = 75.1 bits (183), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 103/422 (24%), Positives = 172/422 (41%), Gaps = 63/422 (15%)
Query 562 LQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW-------- 612
L ++ I +SQ+S + D + L + + V YI V +L +Q+
Sbjct 562 LIQSGIFFTSLMSQFSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLV 621
Query 613 --LTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKE 670
+ N F T+ + P WL + G+ F+ + A I AK
Sbjct 622 NKMVNWFNTMLDASAPATGWLLYQLLNGL-----------FVVSQANFNFVALIPDYAKI 670
Query 671 IKESVQTFFKLVNKFLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSRE 725
+ TFFKL+ L ++ LK +N +G F S GL
Sbjct 671 LVNKFYTFFKLL---LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI-------- 719
Query 726 ETGLLMPLKA-PKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTP 782
G ++P A ++I F EG + E V+++ ++ ++ S E + P
Sbjct 720 -PGFVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEK 771
Query 783 VCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGG-----APTKVTFGDDTVI-EVQGY 836
+CI M + K +K+ P +M N L A KV F + V+ E+
Sbjct 772 ICIIDNMYMG-KCGDKF---FPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 837 KSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPL 893
+V + F+LD D +L + CS + VE G V++F VV DA+ L E + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQV 887
Query 894 GIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTE 952
L++ + YLFDE+G+ +AS MYC+F D ED + E+ + + +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 953 DD 954
+D
Sbjct 948 ED 949
Score = 43.1 bits (100), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 36/148 (24%), Positives = 64/148 (43%), Gaps = 16/148 (11%)
Query 1658 YPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAY 1717
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1145 YFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTT 1204
Query 1718 CNKTV--GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
K + + G V + + ++++ N C CG L G++A+ + G +
Sbjct 1205 IPKAIVLPQGGFVADFAYWFLNQFDINA---YANWCCLKCG-FSFDLNGLDALFFYGDI- 1259
Query 1776 YEQFKKGVQIPCTCGKQATKYLVQQESP 1803
V C CG T L+ + P
Sbjct 1260 -------VSHVCKCGHNMT--LIAADLP 1278
>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180
Score = 5337 bits (13844), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2744/5655 (49%), Positives = 3663/5655 (65%), Gaps = 213/5655 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ V TVD +N + V +G+ G + DG +VTK++ H+GK F+
Sbjct 1610 VDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIHKGKVFFQYSGLSAA 1669
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
+ A + D L +Y S L K W + K ++NNCY+ A L LQ +
Sbjct 1670 DLAAVKDAFGFDEPQLLQYYSMLGMCK-WPVVVCGNYFAFKQSNNNCYINVACLMLQHLS 1728
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF + R+G+ F +L+LA + E D + + + A+L
Sbjct 1729 LKFPKWQWRRPGNEFRSGKPLRFVSLVLAKGSFKFNEPSDSTDFIRVELREADLSGATCD 1788
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
L +CK CG +Q KGV+AVM+ GTL KG I CTCG + + Q PF++
Sbjct 1789 LEFICK-CGVKQEQRKGVDAVMHFGTLDKSGLVKGYNIACTCGDKLV-HCTQFNVPFLIC 1846
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S P +L A+ +TG GHY H+ K D ++K SE KG TD
Sbjct 1847 SNTPEGKKLPDDVVA-ANIFTGG-SVGHYTHVKCKPKYQLYDACNVSKVSEAKGNFTDCL 1904
Query 1868 YKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPNAS-- 1924
Y +N T + TY LD V C P L YY + Y+T +PI + +
Sbjct 1905 YLKNLKQTFSSVLTTYYLDDVKCVAYKPDLSQYYCESGKYYT-KPIIKAQFRTFEKVEGV 1963
Query 1925 FDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK V +I A+ LN G+ E K+T +P GDVV Y + G
Sbjct 1964 YTNFKLVGHDI--AEKLNAKLGFDCNSPFMEYKITEWPTATGDVVLASDDLYVSRYSGGC 2021
Query 1984 KLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVETSNSFD------------- 2026
KP++W H + TY +P+ C ++ PV+ S D
Sbjct 2022 VTFGKPVIWRGHEEASLKSLTYFNRPSVVC-ENKFNVLPVDVSEPTDRRPVPSAVLVTGA 2080
Query 2027 -------VLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVG------ 2073
+ +E + AC V +++V + V VK ++ G
Sbjct 2081 ASGADASAISTEPGTAKEQKACAS-DSVEDQIVMEAQKKSSVTTVAVKEVKLNGVKKPVK 2139
Query 2074 ---DIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATH---GL 2127
+++ + K+ + + D+ ++ + NELSR++ T+ + G+
Sbjct 2140 WNCSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWTANELSRLINSPTVREYVKWGM 2199
Query 2128 AAVNSVPWDTI--ANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRS 2185
+ + +P + + + + F+ V I C + +F F
Sbjct 2200 SKL-IIPANLLLLRDEKQEFVAPKVVKAKAIA-------CYGAVKWFLLYCFSWIKF--- 2248
Query 2186 TNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLIN--------IIIWF--LL 2235
N+ K T +A K K C A N L++ N+S + ++WF L
Sbjct 2249 -NTDNKVIYTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVFLLWFNFLY 2304
Query 2236 LSVCLGSL---------IYSTAALGVLMSNLGMPSYCTGYRE---GYLNSTNVTIATYCT 2283
+V L ++ + + + G+ + C Y+ GY +S +C
Sbjct 2305 ANVILSDFYLPNIGPLPMFVGQIVAWVKTTFGVLTICDFYQVTDLGYRSS-------FCN 2357
Query 2284 GSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
GS+ C +C SG D LD Y S+ +Q + SF + ++ F LV E + Y L+T FY
Sbjct 2358 GSMVCELCFSGFDMLDNYESINVVQHVVDRRVSFDY-ISLFKLVVELVIGYSLYTVCFYP 2416
Query 2341 LGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYV 2398
L + MQL ++ F+ + W L + + M P ++R YI + Y V+
Sbjct 2417 LFVLVGMQLLTTWLPEFFMLGTMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVYCLCR 2476
Query 2399 HVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTF 2458
HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC+NC+++
Sbjct 2477 HVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLNCNSW 2536
Query 2459 CAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSL 2518
G+TFI+ E A DLS + KRP+NPTD + Y V V S+ L++++ GQ+ Y+ S
Sbjct 2537 KPGNTFITHEAAADLSKELKRPVNPTDSAYYSVIEVKQVGCSMRLFYERDGQRVYDDVSA 2596
Query 2519 SHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVS 2578
S FV+++ L + KG +V+V + ++ +++ +A+V+Y+Q + +P+L++++ L++
Sbjct 2597 SLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRPMLMVEKKLIT 2654
Query 2579 DVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAAR 2638
V+ MFD YV + +V + L + V A L + V L+ V+ TF+ AR
Sbjct 2655 TANTGLSVSRTMFDLYVYSLLRHLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFVGCAR 2714
Query 2639 QG-FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSAR 2697
+ +DSDVETK + + + + + +EVT +SCNN + TY K + + DLG I +A+
Sbjct 2715 RKCAIDSDVETKSITKSVMAAVNAGVEVTDESCNNLVPTYVKSDTIVAADLGVLIQNNAK 2774
Query 2698 HINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTK 2757
H+ + VAK+ N+A IW+V F LS L+ ++R A K L KLT V ++TT
Sbjct 2775 HVQSNVAKAANVACIWSVDAFNQLSADLQHRLRKACVKTGLKIKLTYNKQEANVPILTTP 2834
Query 2758 IALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVT 2817
+LKGG + + L+ L L+ V + + P + + K +K ID GV
Sbjct 2835 FSLKGGAVFSRVLQWLFVANLICFIV---LWALMPTYAVHKSDMQLPLYASFKVIDNGVL 2891
Query 2818 RDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILR 2875
RD++ TD CFANK FD W+ G Y N KACP++ AVI +++G + +P +LR
Sbjct 2892 RDVSVTDACFANKFNQFDQWYESTFGLVYYRNSKACPVVVAVIDQDIGHTLFNVPTKVLR 2951
Query 2876 TTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYD 2935
LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P PYCY
Sbjct 2952 Y-GFHVLHFITHAFATDRVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHPYCYT 3010
Query 2936 TNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEA 2994
V+ + Y SL P RY L + I+FP EG VRVV T YCR G CE +E
Sbjct 3011 EGVMHNASLYSSLVPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLCEEAEE 3070
Query 2995 GVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVA 3054
G+C + + WVLNN YYR++PG FCG +A +L+ + L+QPI ++AS VAG I+A
Sbjct 3071 GICFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVQPIDFFALTASSVAGAILA 3130
Query 3055 IVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTF 3114
I+V YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L +Y+ Y Y T
Sbjct 3131 IIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFYTTL 3190
Query 3115 YLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFST 3174
Y +++S + H+QW+VM+ ++P W I Y+ + + H W FS R++ + S T
Sbjct 3191 YFPSEISVVMHLQWLVMYGAIMPLWFCITYVAVVVSNHALWLFS--YCRKIGTDVRSDGT 3248
Query 3175 FEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL 3234
FEE AL TF++ KE Y KL++ V +NRYL+LYNKY+YFSG MDT +YREAAC L
Sbjct 3249 FEEMALTTFMITKESYCKLKNSV--SDVAFNRYLSLYNKYRYFSGKMDTATYREAACSQL 3306
Query 3235 AKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
AKA+ F+ N+G+DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G TLNGL
Sbjct 3307 AKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCVVSVTYGNMTLNGL 3366
Query 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
WLDD VYCPRHVIC+S DM +P+Y +LL R ++ +F V + + L V+ + MQ +L L
Sbjct 3367 WLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSDRMSLTVMSYQMQGSLLVLT 3426
Query 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
V NP TPKY F ++PG+TF+VLA YNG P G + MR + TIKGSFL GSCGSVG+
Sbjct 3427 VTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVVMRSSHTIKGSFLCGSCGSVGY 3486
Query 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
+ D V F YMH +EL TG H GTD GNFYGP+ D Q Q D T TVNV+AWLYA
Sbjct 3487 VLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAWLYA 3546
Query 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
A++N WF+ + +L +FN+ AM + + D V L L++ TG+ V + A++K
Sbjct 3547 AILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVLAAIKR 3604
Query 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
L +G G+ ILGS +LEDE TP DV +Q +GV QS R IKGT W+L + +
Sbjct 3605 L-HSGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTFLFCSI 3663
Query 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
+ +W++F ++ + L + + FAM+ +KHKH +L ++++P L T+ Y N +
Sbjct 3664 ISAFVKWTMFMYVTTH-MLGVTLCALCFVIFAMLLIKHKHLYLTMYIMPVLCTLFYTNYL 3722
Query 3654 YMPASWVMRIMT--WLDMVDTSLSGFKLKDCVMYASAVVLLILM---TARTVYDDGARRV 3708
+ R + WL ++ + D V+Y VVLL+ M T R++ D +
Sbjct 3723 VVGYKQSFRGLAYAWLSYFVPAVD-YTYMDEVLYG--VVLLVAMVFVTMRSINHDVFSTM 3779
Query 3709 WTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARG-IVFMCVEYCP 3767
+ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA ++ +
Sbjct 3780 FLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKWLAVNV 3835
Query 3768 IFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQG 3827
++F ++ ++L Y +GY C CY+G+ LLN FR+ LGVY+Y +S QE RYMN+ G
Sbjct 3836 LYFTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISVQELRYMNANG 3895
Query 3828 LLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKL 3887
L PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+SKL
Sbjct 3896 LRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNSKL 3955
Query 3888 WAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATL 3941
W C LHN+IL D + AF+K+ LL VL + AVD I ++ ++ + + L
Sbjct 3956 WQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNTVL 4015
Query 3942 QAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRK 4000
QA+ SEF ++ S+ + A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ RK
Sbjct 4016 QALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARK 4075
Query 4001 LEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLN 4060
LE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN
Sbjct 4076 LERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLN 4135
Query 4061 IIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSP 4120
IP T+ L +++PD + D TYA +W IQ + DAD + QL+EI ++++
Sbjct 4136 AIPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDVNST- 4194
Query 4121 NLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGG 4178
WPL+++A R N S V LQNNEL P LR +G+ + YYNTT G
Sbjct 4195 ---WPLVISANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNC--NIPTQCYYNTTGTG 4249
Query 4179 RFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLN 4238
+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L
Sbjct 4250 KIVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNTLA 4308
Query 4239 RGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKML 4298
RG V+G+L++TVRLQAG ATE +NS +LS CAF+VD K Y DY+ GG P+TNCVKML
Sbjct 4309 RGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIQQGGVPVTNCVKML 4368
Query 4299 CTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCAN 4358
C H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P
Sbjct 4369 CDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-IK 4427
Query 4359 DPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTG 4417
DPV + L + VC VCG W+ CSC QS D +FLNRV G S ARL PC +G
Sbjct 4428 DPVSYVLTHDVCQVCGFWRDGSCSCVGTGS-QFQSKDT-NFLNRVRGTSVNARLVPCASG 4485
Query 4418 TSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEET 4477
TDV RAFDI N AG + K NC RFQ DE+ N +D +FVVKR Y E+
Sbjct 4486 LDTDVQLRAFDICNANRAGIGLYYKVNCFRFQRVDEEGNKLDKFFVVKRTNLEVYNKEKE 4545
Query 4478 IYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEI 4537
Y L KDC VA+H+FF F ++G VPHI R+ L+K+TM DL YALRHFD +C TLKEI
Sbjct 4546 CYELTKDCGVVAEHEFFTFDVEGSRVPHIVRKDLSKFTMLDLCYALRHFDRNDCSTLKEI 4605
Query 4538 LVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVL 4597
L+TY CD+ YF KKDWYDFVENPDI+ VY LG +ALL T F D + AG+VGVL
Sbjct 4606 LLTYAECDESYFQKKDWYDFVENPDIINVYKKLGPIFNRALLNTANFADTLVEAGLVGVL 4665
Query 4598 TLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPY 4657
TLDNQDL G WYDFGDF++T P GV V DSYYS +MP+LT+ AL +E V+ Y
Sbjct 4666 TLDNQDLYGQWYDFGDFVKTVPCCGVAVADSYYSYMMPMLTMCHALDSELFVN----GTY 4721
Query 4658 IKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTS 4717
++DL++YDFT+ +L+LF++YFK+W TYHPN C DDRCI+HCANFN+LFS V P T
Sbjct 4722 REFDLVQYDFTDFKLELFNKYFKHWSMTYHPNTSECEDDRCIIHCANFNILFSMVLPKTC 4781
Query 4718 FGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASG 4777
FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+LL+YAADPA+H AS
Sbjct 4782 FGPLVRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYRLSLKDLLLYAADPALHVASA 4841
Query 4778 NLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQD 4837
+ LLD RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +SKG KEGSSV+LKHFFF QD
Sbjct 4842 SALLDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSVDLKHFFFTQD 4901
Query 4838 GNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFP 4897
GNAAI+DY+YY+YNLPTM DI+QLLFVVEVV+KYF+ Y+GGCI A QVIVNN DKSAG+P
Sbjct 4902 GNAAITDYNYYKYNLPTMVDIKQLLFVVEVVNKYFEIYEGGCIPATQVIVNNYDKSAGYP 4961
Query 4898 FNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICST 4957
FNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI ST
Sbjct 4962 FNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILST 5021
Query 4958 MTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRA 5017
MT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPKCDRA
Sbjct 5022 MTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPKCDRA 5081
Query 5018 MPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDA 5077
MPN+LRI++SLVLARKH +CCS + RFYRLANECAQVL E+VMCGG YVKPGGTSSGDA
Sbjct 5082 MPNILRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLGEIVMCGGCYYVKPGGTSSGDA 5141
Query 5078 TTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEF 5137
TTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD FV+E+
Sbjct 5142 TTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVSEY 5201
Query 5138 YAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDL 5197
Y +L KHFSM+ILSDD VVC+NS +AS+G +A+I +F+ VLYYQNNVFMSEAKCW ETD+
Sbjct 5202 YEFLNKHFSMIILSDDGVVCYNSEFASKGYIANISDFQQVLYYQNNVFMSEAKCWVETDI 5261
Query 5198 TKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAID 5257
KGPHEFCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFVSLAID
Sbjct 5262 EKGPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFVSLAID 5321
Query 5258 AYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMY 5317
AYPL H N EY +VF +YL+YI+KL+++L +LD SV+L+ + ++ + FY+ MY
Sbjct 5322 AYPLVYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSISVILSTCDGQKFTDETFYKNMY 5381
Query 5318 TPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAP 5377
V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC YDHV+ST HK VLSV+PYVCN+P
Sbjct 5382 LRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVLSVSPYVCNSP 5441
Query 5378 GCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCD 5437
GCDV DVT+LYLGGMSYYC++HKP SF L NG VFGLYK +C GS + DFN IA+C
Sbjct 5442 GCDVNDVTKLYLGGMSYYCEAHKPQYSFKLVMNGMVFGLYKQSCTGSPYIEDFNKIASCK 5501
Query 5438 WTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPR 5497
WT DY+LAN CTERLKLFAAET KATEE FK Y AT+RE++SDREL LSWE+GK R
Sbjct 5502 WTEVDDYVLANECTERLKLFAAETQKATEEAFKQCYASATIREIVSDRELILSWEIGKVR 5561
Query 5498 PPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVM 5557
PPLN+NYVFTGY T N K +GEY F+K + + V YR TTTYKL+VGD F+LTSH V
Sbjct 5562 PPLNKNYVFTGYHFTNNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFILTSHAVS 5621
Query 5558 PLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHF 5615
LSAPTLVPQE+Y VR Y ++ + F +NV NYQ +G+++Y T+QGPPGTGKSH
Sbjct 5622 SLSAPTLVPQENYTSVRFASAY---SVPETFQNNVPNYQHIGIKRYCTVQGPPGTGKSHL 5678
Query 5616 AIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNST 5675
AIG A+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RV+C+DKF VN T
Sbjct 5679 AIGHAVYYCTARVVYTAASHAAVDALCEKAHKFLNINDCARIVPAKLRVDCYDKFNVNDT 5738
Query 5676 LEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTL 5735
+YVF T+NALPE DI+V DE+SM TNY+LSV+N+R+RAKHYVYIGDPAQLPAPR L
Sbjct 5739 TRKYVFTTINALPELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGDPAQLPAPRVL 5798
Query 5736 LTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQC 5795
L KGTLEP YFNSV +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA D SA C
Sbjct 5799 LNKGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYNNKLKAKNDNSAMC 5858
Query 5796 FKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQ 5855
FK++YKG TH+ SSA+N QI ++ + L NP+W AVFISPYNSQN VA ++LGL TQ
Sbjct 5859 FKVYYKGQTTHESSSAVNMQQIHLISKLLKANPSWSNAVFISPYNSQNYVAKRVLGLQTQ 5918
Query 5856 TVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLE 5915
T DS+QGS YD+VI++QT +TAHS NVNRFNVAITRAK GILC+MS L FT+L
Sbjct 5919 TADSAQGSAYDFVIYSQTAQTAHSVNVNRFNVAITRAKKGILCVMSSMQLIGVFNFTTLT 5978
Query 5916 IPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDM 5974
+ + N LQ T LFKDCSK G+ P L+VD K+K G L V + +
Sbjct 5979 LDKINNPRLQC--TTNLFKDCSKSYVGIPP--CAFLLAVDDKYKVSGNLAVCLNVADSAV 6034
Query 5975 TYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQL 6034
TY RLIS+MGFK++ ++GY +FITR+EAI+ VRAW+GFD EG HATR+++GTN PLQL
Sbjct 6035 TYSRLISLMGFKLDLTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHATRDSIGTNFPLQL 6094
Query 6035 GFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQM 6094
GFSTG++ V TG + F + +A+ PPG+QFKHL+PLM +G W+VVRI+IVQM
Sbjct 6095 GFSTGIDFVVEATGMFAERDGYVFKKAAARAPPGEQFKHLVPLMSRGQKWDVVRIRIVQM 6154
Query 6095 LSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHH 6154
LSD L +L+D VV V WA FELT ++YF K+G E C +C++RATCF++ + Y CW H
Sbjct 6155 LSDHLVDLADSVVLVTWAASFELTCLRYFAKVGKEVVCSVCNKRATCFNSRTGYYGCWRH 6214
Query 6155 SIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKR 6214
S DY+YNP ++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+CF K
Sbjct 6215 SYSCDYLYNPLIVDIQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRCLAVHDCFCKS 6274
Query 6215 VDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWK 6274
V+W +EYPII +E+ +N +CR +Q ++ +AA+L +++ V +DIGNPK + CV D +K
Sbjct 6275 VNWNLEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKGYD--FK 6332
Query 6275 FYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNL 6334
FYDA P +++ Y Y H D+F DG+C+FWNCNVD+YPAN++VCRFDTRVLS L
Sbjct 6333 FYDASPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLSKL 6389
Query 6335 NLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLK 6394
NLPGC+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD+PC +DYVPL+
Sbjct 6390 NLPGCNGGSLYVNKHAFHTNPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLR 6449
Query 6395 SATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSL 6454
SATCITRCNLGGAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFTRLQSL
Sbjct 6450 SATCITRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQSL 6509
Query 6455 ENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRN 6514
ENV +N+VN GHFDG+ GE+P ++I V K+ DV +F+N T P NVA EL+A+R+
Sbjct 6510 ENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAERS 6569
Query 6515 IKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVF 6574
I+P PE+K+ + + + N V+WDY +D+ ST VC TD+ L V
Sbjct 6570 IRPHPELKLFRSSNIHVCWNHVLWDYAKDSVFCSSTYKVCKYTDL------QCIESLNVL 6623
Query 6575 FDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEA-VKTQFNYY 6631
FDGR +G ++ F+ RNGV I +K L GP++A LNGV + +G++ V+ F
Sbjct 6624 FDGRDNGALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFAMR 6683
Query 6632 KKVDGVV-----------QQLPE--------------------TYFTQSRNLQEFKPRSQ 6660
+ D V+ + P+ T FTQSR L F PRS+
Sbjct 6684 RDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRFLSSFSPRSE 6743
Query 6661 MEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDF 6720
ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHLLIGLA+R K+S +++F
Sbjct 6744 MEKDFMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRPKKSNLVIQEF 6803
Query 6721 IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEIS 6780
+P DS++ +YFITD +GSS+ VC+VIDLLLDDFV+I+KS +L VSKVV V +D+ +
Sbjct 6804 VPYDSSIHSYFITDENSGSSESVCTVIDLLLDDFVDIVKSLNLKCVSKVVNVNVDFKDFQ 6863
Query 6781 FMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMM 6840
FMLWC + V TFYP+LQ++ W+PG MP LYK +E+ +L NYG TLP G MM
Sbjct 6864 FMLWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPMERVNLWNYGKPITLPTGCMM 6923
Query 6841 NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND 6900
NVAKYTQLCQYL+T TLAVP NMRV+H GAGSDKGVAPG+AVLRQWLP+G++LVD+D+N
Sbjct 6924 NVAKYTQLCQYLSTTTLAVPANMRVLHLGAGSDKGVAPGSAVLRQWLPSGSILVDNDMNP 6983
Query 6901 FVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLA 6960
FVSD+ ++ G+C T+ +WDLIISDMYDP TKN+ + N SK+GFFTY+C I+ KLA
Sbjct 6984 FVSDSVASYYGNCITLPFDCQWDLIISDMYDPLTKNIGEYNVSKDGFFTYLCHLIRDKLA 7043
Query 6961 LGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGY 7020
LGGSVAIKITE SWNA+LY LMG FA+WT F TNVNASSSE FLIG N+L + R +IDG
Sbjct 7044 LGGSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWLNRTRNEIDGK 7103
Query 7021 VMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLII 7080
MHANY+FWRN+ +YSLFDM+KFPLK GTAV+SLK QIND++LSL+ KG+L++
Sbjct 7104 TMHANYLFWRNSTMWNGGAYSLFDMTKFPLKAAGTAVVSLKPDQINDLVLSLIEKGKLLV 7163
Query 7081 RENNRVVISSDVLVN 7095
R+ + V D LVN
Sbjct 7164 RDTRKEVFVGDSLVN 7178
Score = 88.6 bits (218), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 236/1025 (23%), Positives = 393/1025 (38%), Gaps = 219/1025 (21%)
Query 2 ESLVPGFNEKTHVQLS---LPVLQ-------VRDVLVRGFGDSVEEVLSEARQHLKDGTC 51
E V G HV++ LP L+ +RD+ V + ++V + L+ G+
Sbjct 46 EPKVKGKTLVNHVRVDCSRLPALECCVQSAIIRDIFV---DEDPQKVEASTMMALQFGSA 102
Query 52 GLVEVEK----------GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQY 97
LV+ K GVLP+ +F + T HV +L + +G+
Sbjct 103 VLVKPSKRLSVQAWAKLGVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCL 162
Query 98 GRSGETLGVLVPHVGEIPVAYRK------VLLRKNGNKGA---GGHSYGADLKSFDLGDE 148
G +G +G VP V IP ++ +LLRK GNKG+ G + +D E
Sbjct 163 G-NGRFIGWFVP-VTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE 220
Query 149 LGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARA 208
D E+ N K+S L+R G +VD C G C+ L
Sbjct 221 ---DACEEVHLNPRGKYSCK-AYALLRGYRGVKPILFVDQYGCDYTG----CLAKGLEDY 272
Query 209 GKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKS-YELQTPFEIKLAKKF---- 263
G TLSE + R ++E +AW+ +R ++ LQT ++ +
Sbjct 273 GDL--TLSEMKELSPVWRDSL---DNEVVVAWHVDRDPRAVMRLQTLATVRSIEYVGQPI 327
Query 264 -DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLS 318
D +G+ P + N+I+K + PR+ + L + + + C
Sbjct 328 EDMVDGDVVMREPAHLLAPNAIVKRL-PRLVETML-------------YTDSSVTEFCYK 373
Query 319 TLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPAC----- 373
T + CD CG + Q G +V + CG G++P N + CP C
Sbjct 374 TKL-CD-CGFIT-QFG-YVDCCGDTCGFR----------GWVPGNMMDGFPCPGCCKSYM 419
Query 374 ------HNSEVGPEHSL--AEYHNESGLKTILRKGGRTIAFGGCVF--SYVGCHNKCAYW 423
+S V PE + + + ++ G + FGG + Y G W
Sbjct 420 PWELEAQSSGVIPEGGVLFTQSTDTVNRESFKLYGHAVVPFGGAAYWSPYPG------MW 473
Query 424 VPRASANIGC----NHTGVVG-EGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILA 478
+P +++ +TGVVG + D + L + V + G+ E+ AI+
Sbjct 474 LPVIWSSVKSYSYLTYTGVVGCKAIVQETDAICRFLYMDYVQ-HKCGNL---EQRAIL-- 527
Query 479 SFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFAS 538
GLD +Q++ + G++ + +L + F
Sbjct 528 --------------GLDDVYHRQLLVNRGDYSL-----------------LLENVDLFVK 556
Query 539 EAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA-MMFTSDLATNNLVV 597
R+ F+ T + + L +LDG+ S LI + FTS + + V
Sbjct 557 R-----RAEFACKFATCGDGLVPL------LLDGLVPRSYYLIKSGQAFTSLMVNFSREV 605
Query 598 ------MAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRD------G 645
MA + V++ ++++ + G V + K + + K E + D G
Sbjct 606 VDMCMDMALLFMHDVKVATKYVKKVTGKVAVRFKALGIAVVRKITEWFDLAVDTAASAAG 665
Query 646 WEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNL 705
W + ++ V ++T +E+ E V+ F F + DS+ + ++
Sbjct 666 WLCYQLVN--GLFAVANGVITFIQEVPELVKNFVDKFKTFFKVLIDSMSV------SILS 717
Query 706 GETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVL---TEEVVLKTGD 762
G T V + R C+ A ++ + ++LP ++ E G+
Sbjct 718 GLTVVKTASN--RVCL-------------AGSKVYEVVQKSLPAYIMPVGCSEATCLVGE 762
Query 763 LQP--LEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEK-YCALAPN----MMVTNNTFTL 815
++P E + V+APL C +I +K Y A + ++V N+T +
Sbjct 763 IEPAVFEDDVVDVVKAPLTYQGCCKPPSSFEKICIVDKLYMAKCGDQFYPVVVDNDTVGV 822
Query 816 KGG------APTKVTFGDD-TVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEV 868
A KV F D V EV + + I F LD D VL++ CS + V+ +
Sbjct 823 LDQCWRFPCAGKKVVFNDKPKVKEVPSTRKIKIIFALDATFDSVLSKACSEFEVDKDVTL 882
Query 869 NEFACVVADAVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFY 925
+E VV DAV TL P E + T + L+ YLFDE GE +AS MYCSF
Sbjct 883 DELLDVVLDAVESTLSPCKEHGVIGTKVCALLERLVDDYVYLFDEGGEEVIASRMYCSFS 942
Query 926 PPDED 930
PDED
Sbjct 943 APDED 947
Score = 59.3 bits (142), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 52/153 (34%), Positives = 82/153 (54%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV D+++ ++V V+VN AN + HG GVAGA+ KA A E+ D +
Sbjct 1319 ITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKAFINETADMVKA 1378
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNV--NKGEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G +VGG +G L K L++VGP+ + E LL+ AY++ N+ + ++ L+SA
Sbjct 1379 QGVCQVGGCYESTGGKLCKKVLNIVGPDARGHGNECYSLLERAYQHINKCDNVVTTLISA 1438
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + V NV L +++ +D
Sbjct 1439 GIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFD 1471
Score = 40.0 bits (92), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 52/213 (24%), Positives = 84/213 (39%), Gaps = 25/213 (12%)
Query 1596 PTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLR-VEAFEYYHTTDPSFLGRYMSALNHTK 1654
P ++ D+ K++ E +T P D T V AF+ ++ S S H K
Sbjct 1047 PDQVEAFDIEKVEDSILSELQTELNAPADKTYEDVLAFDAIYSETLSAFYAVPSDETHFK 1106
Query 1655 KWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALI 1714
V G S NC+L + L+ +Q + L+F +Q + +AG F +
Sbjct 1107 ------VCGFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKL 1160
Query 1715 LAYCNKT-VGELGDVRETMSYLFQHANLDSC--KRVLNVVCKTCGQQQTTLKGVEAVMYM 1771
+ K+ + G +Y F L C K N C CG + L+G++AV +
Sbjct 1161 VKSAPKSIILPQGGYVADFAYFF----LSQCSFKVHANWRCLKCG-MELKLQGLDAVFFY 1215
Query 1772 GTLSYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
G + V C CG T L+ + P+
Sbjct 1216 GDV--------VSHMCKCGNSMT--LLSADIPY 1238
>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059
Score = 5261 bits (13647), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2699/5564 (49%), Positives = 3632/5564 (65%), Gaps = 200/5564 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + + D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTV--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLK-PVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
D K P +++ ++K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAKEPKEINIIKLSGVKKPF--------KVEDSVIVNDDTSEIKYVKSLSIVDVYDMWL 2079
Query 2101 DNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNI 2156
++ N LSR + + T+ G+ V S+P D + KP N VV N
Sbjct 2080 TGCRCVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNK 2137
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
++ C N ++ + F LL + K T +A + + +F
Sbjct 2138 ISACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFL 2188
Query 2217 YLKSPNFSKLINII--IWFLLLSVCLGSLIYST---AALGVLMSNLG-----------MP 2260
K ++ II I+ L + ++I+S +G L + +G +
Sbjct 2189 TFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIVQWIKNTFSLV 2248
Query 2261 SYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTA 2320
+ C Y + N YC GSI C CL+G D LD Y +++ +Q ++ D A
Sbjct 2249 TICDLYSIQDVGFKN----QYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRA 2299
Query 2321 F-------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINL 2371
F +V E ++Y L+T +FY L +Q+ ++ + ++ W + L+++L
Sbjct 2300 FVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELLMLSTLHWSVRLLVSL 2359
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
M P +R YI ASF ++ + HV GC+ S C+ CYKRNR+ RV+C+TIV G+
Sbjct 2360 ANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMI 2419
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2420 RYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTV 2479
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEE 2551
V + L++D+ GQ+TY+ + S FV+ NL + K ++V+V + + ++
Sbjct 2480 TDVKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DK 2537
Query 2552 SSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKT 2611
++ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L
Sbjct 2538 ANFLNAAVFYAQSLFRPILMVDKILITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNA 2597
Query 2612 LVATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSC 2670
L+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SC
Sbjct 2598 LIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESC 2657
Query 2671 NNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIR 2730
NN + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2658 NNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLK 2717
Query 2731 SAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLI 2790
A K L +LT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2718 KACCKTGLKLELTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLV-CFIG--LWCL 2774
Query 2791 TPVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTN 2847
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2775 MPTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2848 DKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTD 2907
ACP++ AV+ ++ G V +P +LR LHF+ SA G CYTP I Y++
Sbjct 2834 SMACPIVVAVVDQDFGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2908 FATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPN 2966
F S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+ P
Sbjct 2893 FYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRLPE 2952
Query 2967 TYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNL 3026
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L
Sbjct 2953 VLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3027 LTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL 3086
+ +F L QP+ L ++AS +AG I+A++V YY ++ +RAFG+Y+ +V N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLGFYYLIKLKRAFGDYTSIVFVNVIVWC 3072
Query 3087 MSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYII 3146
++F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIS 3132
Query 3147 CISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ + H +W FS R++ + S TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVFS--YCRQLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSG 3265
YL+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3266 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKS 3325
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3326 NHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSP 3385
+ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3386 SGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFY 3445
G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3446 GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3505
GP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQV 3488
Query 3506 TQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSG 3565
D V + L++ TG+++ + A++K L +NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3566 VTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFA 3625
+ QS R +KG W++ + ++ +W++F ++ N L + + + A
Sbjct 3546 IKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLA 3604
Query 3626 MMFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
M+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+
Sbjct 3605 MLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3685 YASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSN 3743
Y +++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+
Sbjct 3664 YGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGT 3721
Query 3744 YSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
Y+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N
Sbjct 3722 YTWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSL 3780
Query 3804 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMS 3863
FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++
Sbjct 3781 FRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLT 3840
Query 3864 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3923
DVKC + LL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL +
Sbjct 3841 DVKCANGGLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPA 3900
Query 3924 AVD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVV 3976
AVD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + +
Sbjct 3901 AVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQ 3960
Query 3977 LKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTM 4036
LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M
Sbjct 3961 LKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSM 4020
Query 4037 LRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALW 4096
+RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W
Sbjct 4021 VRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVW 4080
Query 4097 EIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSC 4154
+IQ + D+D QL EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4081 QIQTIQDSDGTNKQLHEISDDCN----WPLVIIANRHNEVSATVLQNNELMPAKLKTQVV 4136
Query 4155 AAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCR 4214
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+
Sbjct 4137 NSGPDQTCNTPTQC--YYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCK 4193
Query 4215 FVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAV 4274
F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+V
Sbjct 4194 FTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSV 4253
Query 4275 DAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHI 4334
D K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR +
Sbjct 4254 DPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCRARV 4313
Query 4335 DHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA 4394
+HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS
Sbjct 4314 EHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSK 4371
Query 4395 DAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDE 4453
D +FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRFQ DE
Sbjct 4372 DT-NFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRFQRVDE 4430
Query 4454 DDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTK 4513
+ + +D +FVVKR + Y E Y +KDC VA+HDFF F ++G VPHI R+ LTK
Sbjct 4431 NGDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKDLTK 4490
Query 4514 YTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGER 4573
YTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY LG
Sbjct 4491 YTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKLGPI 4550
Query 4574 VRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLL 4633
+AL+ +F D + G+VG+LTLDNQDLNG WYDFGD++ PG GV + DSYYS +
Sbjct 4551 FNRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYYSYM 4610
Query 4634 MPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNC 4693
MP+LT+ AL E +V+ Y +DL++YDFT+ +L+LF++YFK+W YHPN V+C
Sbjct 4611 MPMLTMCHALDCELYVNN----AYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNTVDC 4666
Query 4694 LDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNL 4753
DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N DV+
Sbjct 4667 QDDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMDVDT 4726
Query 4754 HSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYD 4813
H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+DFYD
Sbjct 4727 HRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYD 4786
Query 4814 FAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFD 4873
F +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+
Sbjct 4787 FILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFE 4846
Query 4874 CYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQ 4933
YDGGCI A QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQ
Sbjct 4847 IYDGGCIPAAQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQ 4906
Query 4934 MNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNM 4993
MNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +M
Sbjct 4907 MNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDM 4966
Query 4994 LKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQ 5053
L+ + DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS S RFYRLANECAQ
Sbjct 4967 LRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLANECAQ 5026
Query 5054 VLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVR 5113
VLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D +R
Sbjct 5027 VLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDLSIR 5086
Query 5114 NLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKN 5173
LQ RLY +YR+ VD+ FV E+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I
Sbjct 5087 ALQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIANISA 5146
Query 5174 FKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAG 5233
F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYP PSRILGAG
Sbjct 5147 FQQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPVPSRILGAG 5206
Query 5234 CFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLD 5293
CFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL++EL +LD
Sbjct 5207 CFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNELGNQILD 5266
Query 5294 MYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKC 5353
YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC
Sbjct 5267 SYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKC 5326
Query 5354 CYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQV 5413
CYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L NG V
Sbjct 5327 CYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMV 5386
Query 5414 FGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSY 5473
FGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK SY
Sbjct 5387 FGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFKQSY 5446
Query 5474 GIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAV 5533
AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K + + V
Sbjct 5447 ASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELTNGV 5506
Query 5534 VYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVA 5591
YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F +NV
Sbjct 5507 YYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQNNVV 5563
Query 5592 NYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPI 5651
NYQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I
Sbjct 5564 NYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLNI 5623
Query 5652 DKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVV 5711
+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+
Sbjct 5624 NDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYELSVI 5683
Query 5712 NARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAE 5771
NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RCP E
Sbjct 5684 NARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRCPKE 5743
Query 5772 IVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWR 5831
IVDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL NP W
Sbjct 5744 IVDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANPLWH 5803
Query 5832 KAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITR 5891
KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITR
Sbjct 5804 KAVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITR 5863
Query 5892 AKVGILCIMSDRDLYDKLQFTSLEIPRRNVAT-LQAENVTGLFKDCSKVITGLHPTQAPT 5950
AK GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP AP+
Sbjct 5864 AKKGILCVMSNMQLFEALQFTTLTVDKVPQAVETRVQCSTNLFKDCSKSYSGYHPAHAPS 5923
Query 5951 HLSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVR 6009
L+VD K+K G GI +TY RLIS+MGFK++ ++GY +FIT+EEA++ VR
Sbjct 5924 FLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEAVKRVR 5983
Query 6010 AWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGD 6069
AW+GFD EG HATR+++GTN PLQLGFSTG++ V TG + F + AK PPG+
Sbjct 5984 AWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAKAPPGE 6043
Query 6070 QFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPE 6129
QFKHLIPLM +G W+VVR +IVQM +D L +LSD VV V WA FELT ++YF K+G E
Sbjct 6044 QFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFAKVGRE 6103
Query 6130 RTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVH 6189
+C + +RAT +++ + Y CW HS+ DY+YNP ++D+QQWG+ G+L SNHDLYC VH
Sbjct 6104 ISCNVSTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDLYCSVH 6163
Query 6190 GNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLAD 6249
AHVAS DAIMTRCLAV++CF ++W +EYPII +EL IN +CR +Q +++KAA+L +
Sbjct 6164 KGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKAAMLCN 6223
Query 6250 KFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLF 6309
++ + +DIGNPKAI CV D ++KFYDAQP ++ L Y + H D F DG+C+F
Sbjct 6224 RYTLCYDIGNPKAIACVK--DFDFKFYDAQPI---VKSVKTLLYFFEAHKDSFKDGLCMF 6278
Query 6310 WNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPF 6369
WNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +LK +PF
Sbjct 6279 WNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHLKPMPF 6338
Query 6370 FYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISA 6429
FYYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR YL++YN +A
Sbjct 6339 FYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYNTATTA 6398
Query 6430 GFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDG 6489
GF+ WVYK FD YNLWNTFT+LQSLENV +N+V GH+ GQ GE+P +IIN+ V K+D
Sbjct 6399 GFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDK 6458
Query 6490 VDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHIS 6549
DV +F N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY R++ +
Sbjct 6459 EDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSN 6518
Query 6550 TIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGP 6609
T GVC TD+ + L V FDGR +G ++ F+ + NGV I+ VK L GP
Sbjct 6519 TYGVCMYTDLK------LIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGP 6572
Query 6610 KQASLNGVTL--IGE-------AVKTQ-----FNYYKKVDGVVQQLPE------------ 6643
+A LNGV + +G+ AV+ + F+ + + Q P+
Sbjct 6573 PRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVG 6632
Query 6644 --------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHS 6695
T FTQSR + F R+ ME DF+ L D FI++Y LE YAFEHIVYG+F+
Sbjct 6633 GNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQK 6692
Query 6696 QLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFV 6755
+GGLHLLIGL +R + S +++F+ DS++ +YFITD ++G SK VC+VID+LLDDFV
Sbjct 6693 IIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFV 6752
Query 6756 EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKM 6815
++KS +L+ VSKVV V +D+ + FMLWC D V TFYP+LQ++ W+PG +MP LYK
Sbjct 6753 ALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSMPVLYKY 6812
Query 6816 QRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKG 6875
+E+ L NYG TLP G MMNVAKYTQLCQYLNT TLAVP N RV+H GAGS+KG
Sbjct 6813 LNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNTRVLHLGAGSEKG 6872
Query 6876 VAPGTAV----------LRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLI 6925
VAPG+AV LRQWLP GT+LV +DL FVSD+ +T GDC T+ +WDLI
Sbjct 6873 VAPGSAVLRQWLPAGTILRQWLPAGTILVHNDLYPFVSDSVATYFGDCITLPFDCQWDLI 6932
Query 6926 ISDMYDPKTKNVTKENDSKEGFFTYI-CGFIQQKLALGGSVAIKITEHSWNADLYKLMGH 6984
ISDMYD + + +YI C I+ KLALGGSVAIKITE SWNA+LYKLMG+
Sbjct 6933 ISDMYD-----LLLDIGVHVVRCSYIHCHMIRDKLALGGSVAIKITEFSWNAELYKLMGY 6987
Query 6985 FAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIF 7028
FA+WT F TN NASSSE FLIG NYLGKP+ +IDG VMHA F
Sbjct 6988 FAFWTVFCTNANASSSEGFLIGINYLGKPKVEIDGNVMHAIICF 7031
Score = 84.0 bits (206), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T + V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFD 1425
Score = 70.1 bits (170), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 227/1007 (23%), Positives = 370/1007 (37%), Gaps = 179/1007 (18%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIAP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYIKDYKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYAGKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E SV L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSVDSL-GAAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F G I ++ S A G
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYF---GKNIPRYASAVAQAFRSG---- 710
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK +S++ F + I + G+K+ + G + HS L +
Sbjct 711 -AKVGLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP K ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKTKQKGIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRCVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGEFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTED---DY 955
+ + +LFDE+GE LA +YC+F P++D D EE E D
Sbjct 936 KLEDNSLFLFDEAGEEVLAPKLYCAFTAPEDD----DFLEESGVEEDDVEGEETDLTVTS 991
Query 956 QGKPLEFGATSAALQPEEEQE--EDWLDDDSQQTVGQQDGSEDNQTT 1000
G+P A + EE E ED LDD ED Q +
Sbjct 992 AGEP------CVASEQEESSEILEDTLDDGPCVETSDSQVEEDVQMS 1032
>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793
Score = 4347 bits (11274), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2315/4968 (47%), Positives = 3160/4968 (64%), Gaps = 202/4968 (4%)
Query 2171 YFFTLLLQLCTFTRSTNSRIKASMPT---TIAKNTVK---SVGKFCLEASFNYLKSPNFS 2224
Y F+LL + + ++ A +P I K +VK KF F Y+K
Sbjct 1984 YLFSLLAICFRALKKRDMKVMAGVPERTGIILKRSVKYNYKALKFFFRLKFQYIKV---- 2039
Query 2225 KLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTG 2284
FL S+ L +L Y+ + + + +G P C Y +GY NST YC G
Sbjct 2040 --------FLKFSLVLYTL-YALMFMFIRFTPVGTP-ICKRYTDGYANST-FDKNDYC-G 2087
Query 2285 SIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLA 2344
++ C +CL G + L + I K L L + + I+F FF +G+
Sbjct 2088 NVLCKICLYGYEELSDFTHTRVIW---QHLKDPLIGNILPLFYLVFLIIFGGFFVRIGIT 2144
Query 2345 AIMQLFFSY--FAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVD 2402
+ + + A+ + N WL+ L+ P ++M + + + HV+
Sbjct 2145 YFIMQYINAAGVALGYQDNVWLLHLL-------PFNSMGNIIVVAFIVTRILLFLKHVLF 2197
Query 2403 GCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGS 2462
GC+ +C+ C K + TRV TI+ GV +SFYV ANGGK FCK HN+ CV+CD++ G
Sbjct 2198 GCDKPSCIACSKSAKLTRVPLQTILQGVTKSFYVNANGGKKFCKKHNFFCVDCDSYGYGC 2257
Query 2463 TFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFV 2522
TFI+D +A +LS K + PT ++ I+D V NG +LY K + + +
Sbjct 2258 TFINDVIAPELSNVTKLNVIPTGPATIIIDKVEFSNGFYYLYSGSTFWKYNFDITEAKYA 2317
Query 2523 NLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGD 2582
D L+ N + + +VF+ S + K+A VY+SQL+C+PI L+D AL++ +
Sbjct 2318 CKDVLKNCN----ILTDFVVFN-NSGSNVTQVKNACVYFSQLLCKPIKLVDSALLASL-- 2370
Query 2583 SAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFV 2642
+ + + + A+V S++F + + + R+
Sbjct 2371 NVDFSANLHKAFVEVLSNSFGKDLSNCSNM----------------------NECRESLG 2408
Query 2643 DSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVE-NMTPRDLGACIDCSARHINA 2701
SDV ++ + +H+ D+ ++ S NN +++Y K E + D+ C+ A+ +N
Sbjct 2409 LSDVPEEEFSAAVSEAHRYDVLISDVSFNNLIVSYAKPEEKLAVHDIANCMRVGAKVVNH 2468
Query 2702 QVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALK 2761
V N+ ++W KDF++LSE+ RK I K + F LT R + + T +A K
Sbjct 2469 NVLTKDNVPVVWLAKDFIALSEEARKYIVRTTKTKGINFMLTFNDRRMHLTIPTISVANK 2528
Query 2762 GGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIG-----YKAIDGGV 2816
G + + +L + F + LI + V + DFS+++ +K I+ GV
Sbjct 2529 KGAGLPSLFTRL------YSFFWHLCVLIVVLFVATSLLDFSAQVTSDTQYDFKYIENGV 2582
Query 2817 TRDIASTDTCFANKHADFDTWFSQRGGSY-TNDKACPLIAAVITREVGFVVPGLPGTILR 2875
+ C N +F+ W + + GS TN + CP++ + EV ++ PG+P +
Sbjct 2583 LKVFEKPLDCVHNAFVNFNEWHNAKFGSIPTNSRRCPIVVGT-SDEVRYI-PGVPAGVF- 2639
Query 2876 TTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYD 2935
G L F +C+ L + +C+ + CT G+ V YCY
Sbjct 2640 -LYGKSLIFAMSTIFGTSGLCFDDRGLTD-----PDSCIFNSACTTLSGIGGRNV-YCYR 2692
Query 2936 TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCERSEA 2994
V++ + Y SL P + Y LMDG+ I P G +R + T YCR G C S+A
Sbjct 2693 EGVVDNAKLYSSLLPHSYYRLMDGNHIVLPEIITRGFGIRTIKTQAMTYCRTGECIDSQA 2752
Query 2995 GVCVSTSGRWVLNNDYYRSLPG--VFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGI 3052
GVCV +V Y PG CG +LL N+ I +S I+ +
Sbjct 2753 GVCVGLDRFFV-----YSKTPGSDYVCGTGFFSLLFNVIGMFSNSIPVTVMSGQILLNCV 2807
Query 3053 VAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYL 3112
VA + F +F+R FG+ S F L + V L+ V + + + Y L
Sbjct 2808 VAFTAVMACFAFTKFKRLFGDMS----FGVLSVGLCTVVNNLSYVVT-QNSIGMLAYATL 2862
Query 3113 TFYLTNDV--SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VF 3167
F T V S++ H+ + + + L P+W+ +AY+IC + F N K +V +F
Sbjct 2863 YFLCTKGVRYSWVWHVGFAISYCFLAPWWVVLAYLICALLE----FLPNLFKLKVSTQLF 2918
Query 3168 NGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSY 3226
G F +FE AA TF+L+ Y KL + + + +Y A YN+YKY+SG+ Y
Sbjct 2919 EGDKFVGSFESAASGTFVLDMHSYQKLANSI--STEKLKQYCASYNRYKYYSGSASEADY 2976
Query 3227 REAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCG 3286
R A HLAKA++DF+N D LY PP S S LQ+G RKMA PSG VEGC+V+V+ G
Sbjct 2977 RLACFAHLAKAMSDFANDHMDKLYTPPTVSYNST-LQAGLRKMAQPSGIVEGCIVRVSYG 3035
Query 3287 TTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSM 3345
TLNGLWL D V CPRHVI + + ++++ ++ L+R HNF + +GN+ L VI SM
Sbjct 3036 NLTLNGLWLGDTVICPRHVIASNTTNVIDYDHAMSLVRL--HNFSISSGNMFLGVISASM 3093
Query 3346 QNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLN 3405
+ +L +KV+ +N TP Y + ++PG +F++LACY+GS +GVY MR N+TI+GSF++
Sbjct 3094 RGTLLHIKVNQSNVNTPNYTYKVLKPGDSFNILACYDGSAAGVYGVNMRTNYTIRGSFIS 3153
Query 3406 GSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITV 3465
G+CGS G+NI+ V FCYMHH+EL +G H G+D++G YG + D+ T Q G +T
Sbjct 3154 GACGSPGYNINNGVVEFCYMHHLELGSGCHVGSDMDGTMYGKYEDQPTLQIEGASNLVTE 3213
Query 3466 NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVL 3525
NV +WLY A+INGDRW+L+ + ++ +N A++ L +VD L A+TG+ V
Sbjct 3214 NVCSWLYGALINGDRWWLSSVSVGVDTYNEWALRNGMTALK--NVDCFSLLVAKTGVDVG 3271
Query 3526 DMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSA-VKRTIKGTHHWLL 3584
+ AS+++L N G++ILG L DEFT +VV+Q GVT QS V R +
Sbjct 3272 RLLASIQKLHGN-FGGKSILGCTSLCDEFTLSEVVKQMYGVTLQSGKVSRAFRNA----- 3325
Query 3585 LTILTSLLVLVQSTQW--SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLP 3642
+I+ LL L S S F++ P + II S+ M+ VKHK FL L+LLP
Sbjct 3326 -SIVCCLLFLFLSEMLNHSKLFWINPGYITPVFLAIIVASSALMLLVKHKLLFLQLYLLP 3384
Query 3643 SLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYD 3702
SL V+ +N ++ + ++ D GF + + + ++ L T R +
Sbjct 3385 SLCIVSGYN-IFKDYHFYTYMLEEFDY-KVPFGGFNVTGVLNISLCCFVMGLHTFR--FL 3440
Query 3703 DGARRVWT-LMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFM 3761
++++ ++ VLT++Y YY + + LI++ S + T F+ +
Sbjct 3441 QTPNKIFSYVVAVLTVLYTYYY------STDVLGLILTSMSGF----TNYWFIGTATYKL 3490
Query 3762 CVEYCP--IFFITGNTLQCIMLVYCFLGYFCTC-YFGLFCLLNRYFRLTLGVYDYLVSTQ 3818
P + + ++ ++ +Y LGY C C Y+G +NR+ +LTLG Y++ VS
Sbjct 3491 ATYVLPHTSLLDSFDAIKAVVFLYLLLGY-CNCVYYGSLYWINRFCKLTLGCYEFKVSAA 3549
Query 3819 EFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQ 3878
EF+YM + GL P DA L++KL+GVGG+ IK+++VQSK++D+KCT+VVLL L
Sbjct 3550 EFKYMVANGLRAPTGVFDALILSLKLIGVGGRKTIKISSVQSKLTDLKCTNVVLLGCLSN 3609
Query 3879 LRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNR 3938
+ + ++S+ WA CV LHN I L D A E +++LL+ LS A +++L + ++
Sbjct 3610 MNIAANSREWAYCVDLHNKINLCNDAEAAQEMLLALLAFFLSKNSAFGVDELLDSYFNDS 3669
Query 3939 ATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQ 3998
+ LQ++A+ + +LPSY A+ TA+++YE A+ANG ++K+L+ ++NVAKSEFDR+A+ Q
Sbjct 3670 SVLQSVAATYVNLPSYLAYETARQSYEDALANGSPPQLVKQLRHAMNVAKSEFDREASTQ 3729
Query 3999 RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP 4058
RKL++MA+QA +QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I++ A+DG VP
Sbjct 3730 RKLDRMAEQAASQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLAKDGVVP 3789
Query 4059 LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDN 4118
L+IIP +A KL +V+ D +Y YA +W + + D D K V E+ N
Sbjct 3790 LSIIPAVSATKLNIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAKEVVTSN 3849
Query 4119 SPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGG 4178
+LAWPL + R +KLQNNE+ P ++Q A + D NAL Y+ G
Sbjct 3850 VESLAWPLFLNCERI---IKLQNNEIIPSKIKQRPIKA-EGEGVVADGNAL--YSNEGGR 3903
Query 4179 RFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLN 4238
F+ A +SD DLK ++ G+ I ELEPPC+F+ + P GP VKYLYF++ LNNL
Sbjct 3904 TFMYAFISDKPDLKVVKWEFDGGSNAI--ELEPPCKFLVEAPSGPVVKYLYFVRNLNNLR 3961
Query 4239 RGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKML 4298
RG VLG + ATVRLQAG TE NS++L+ CAFAVD K Y D + SG +P+ NCVKML
Sbjct 3962 RGAVLGFIGATVRLQAGKQTEQATNSSLLTLCAFAVDPPKTYLDAVKSGHRPVGNCVKML 4021
Query 4299 CTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCAN 4358
+G GQAIT EA+ +Q+S+GGAS CLYCR H++HP+ GFC L+GKYVQ+P
Sbjct 4022 ANGSGNGQAITNGVEASTNQDSYGGASVCLYCRAHVEHPDMDGFCKLRGKYVQVPLGTL- 4080
Query 4359 DPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGT 4418
DP+ F L+NTVC VCG W+ GC+CD+ ++QS D+ +LNRV G SAARL P G+
Sbjct 4081 DPIRFVLENTVCKVCGCWQANGCTCDR---AVIQSVDS-GYLNRVRGSSAARLEPL-NGS 4135
Query 4419 STDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETI 4478
T V+RAFD+YN VA +KFLK NC R + D+ D ++++VK+ T S +HE++I
Sbjct 4136 DTHHVFRAFDVYNRDVACISKFLKVNCVRLKNLDKHD----AFWIVKKCTKSVMEHEQSI 4191
Query 4479 YNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEIL 4538
YNL+ DC AVAKHDFF ++ + ++ RQ LT+YTM DL YALR+FDE NC+TLK+IL
Sbjct 4192 YNLISDCGAVAKHDFFTWKEGRSVYGNVCRQDLTEYTMMDLCYALRNFDENNCETLKKIL 4251
Query 4539 VTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLT 4598
V CD+ YF+ K W+D VEN D+ RVYA LG V +A+LK V++CDAM GIVGV+T
Sbjct 4252 VVVGACDESYFDNKLWFDPVENEDVHRVYAKLGTIVARAMLKCVKYCDAMVEQGIVGVIT 4311
Query 4599 LDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDL-TKPY 4657
LDNQDLNG++YDFGDF+ + G GVP+ SYYS +MP++ +T L +E + +D+ + +
Sbjct 4312 LDNQDLNGDFYDFGDFVTSVKGMGVPICTSYYSYMMPVMGMTNCLASECFIKSDIFGEDF 4371
Query 4658 IKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTS 4717
+DLL YDFTE ++ LF++YFK+W QTYHPNC +C D+ CI+HCANFN LF+T P T+
Sbjct 4372 RTFDLLAYDFTEHKVNLFNKYFKHWGQTYHPNCEDCHDESCIVHCANFNTLFATTIPITA 4431
Query 4718 FGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASG 4777
FGPL RK ++DGVP V + GYHF++LG+V N+D+NLHSSRL+ ELL + ADP++ AS
Sbjct 4432 FGPLCRKCWIDGVPLVTTAGYHFKQLGIVWNKDLNLHSSRLTINELLQFCADPSLLIASS 4491
Query 4778 NLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQD 4837
L+DKRT CFSVAAL + QTVKPG+FN++FYDF S+GFF+EGS + LKHFFFAQ
Sbjct 4492 PALVDKRTVCFSVAALGTGMTNQTVKPGHFNREFYDFLRSQGFFEEGSELTLKHFFFAQK 4551
Query 4838 GNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFP 4897
G+AA+ D+DYYRYN T+ DI Q V ++V YF Y+GGCI A +VIVNNL+KSAG+P
Sbjct 4552 GDAAVRDFDYYRYNRTTVLDICQARVVYQIVQCYFGMYEGGCITAKEVIVNNLNKSAGYP 4611
Query 4898 FNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICST 4957
FNK+GKA LYYDS+SYE+QD L+AYTKRN+IPT+TQ+NLKYAIS K+RARTV GVS+ ST
Sbjct 4612 FNKFGKAGLYYDSLSYEEQDDLYAYTKRNIIPTMTQLNLKYAISGKDRARTVGGVSLLST 4671
Query 4958 MTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRA 5017
MT RQ+HQK LKSI TRGA+VVIGT+KFYGGW NMLKT+ DVENPHLMGWDYPKCDRA
Sbjct 4672 MTTRQYHQKHLKSIVNTRGASVVIGTTKFYGGWDNMLKTLIKDVENPHLMGWDYPKCDRA 4731
Query 5018 MPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDA 5077
+PNM+R++++++L KH CCS S R+YRL NE AQVL+EMV G YVKPGGT+SGDA
Sbjct 4732 LPNMIRMISAMILGSKHVNCCSSSDRYYRLCNELAQVLTEMVYSNGGFYVKPGGTTSGDA 4791
Query 5078 TTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEF 5137
TTAYANSVFNI QA +ANVN LLS D N + V+ LQ +LY+C YR+ VD FV E+
Sbjct 4792 TTAYANSVFNIFQATSANVNRLLSVDSNTCNNIEVKQLQRKLYDCCYRSSSVDQSFVEEY 4851
Query 5138 YAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDL 5197
+ YLRKHFSMMILSDD VVC+NS YA+ G VA + FK+VLYYQNNVFMS +KCW E D+
Sbjct 4852 FGYLRKHFSMMILSDDGVVCYNSEYAALGYVADLNAFKAVLYYQNNVFMSASKCWIEPDI 4911
Query 5198 TKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAID 5257
KGPHEFCSQHTM + D YLPYPDPSRIL AG FVDDIVKTD +++ER+VSLAID
Sbjct 4912 NKGPHEFCSQHTMQIVDKDGTYYLPYPDPSRILSAGVFVDDIVKTDPVILLERYVSLAID 4971
Query 5258 AYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMY 5317
AYPL+KH N EY VF + L +++ L+ L +LD +SV L D T+++W+ FY +MY
Sbjct 4972 AYPLSKHDNPEYRRVFTVMLDWVKHLYKTLNQGVLDSFSVTLLEDATAKFWDESFYASMY 5031
Query 5318 TPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAP 5377
+VLQ+ G CV+C+SQT LRCG CIRRP LC KC YDHV+STSHK +L++ PYVC +
Sbjct 5032 EQSSVLQSAGLCVVCSSQTVLRCGDCIRRPMLCTKCAYDHVVSTSHKFILAITPYVCCSS 5091
Query 5378 GCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCD 5437
GC V+DVT+LYLGG+SY+C HKP +SFPLC++G VFGLYKN+ GS +V DFN +AT D
Sbjct 5092 GCGVSDVTKLYLGGLSYWCVDHKPRLSFPLCSSGNVFGLYKNSATGSPDVDDFNTLATSD 5151
Query 5438 WTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPR 5497
WT+ DY LAN + L+LFAAET+KA EE+ K SY AT+ EV+ +EL L WEVGKPR
Sbjct 5152 WTDVKDYKLANDVKDSLRLFAAETIKAKEESVKSSYACATIHEVVGPKELVLKWEVGKPR 5211
Query 5498 PPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDY-GDAVVYRGTTTYKLNVGDYFVLTSHTV 5556
PPL+RN VFT Y +TKN+K Q+GE+TFEK DY DAV Y+ T T KL G FVLTSH V
Sbjct 5212 PPLSRNSVFTCYHITKNTKFQVGEFTFEKLDYDNDAVSYKSTATTKLVPGMVFVLTSHNV 5271
Query 5557 MPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFA 5616
PL APT++ QE Y + L P NI +++S+ + YQ +G QK +T+QGPPG+GKSH
Sbjct 5272 QPLRAPTIINQERYSTLHKLRPAFNIHEDYSNLIPYYQLIGKQKLTTIQGPPGSGKSHCV 5331
Query 5617 IGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTL 5676
IGL LY+P ARIV+TACSHAAVD+LC KA D+CSRIIP +AR+EC+D FK N+T
Sbjct 5332 IGLGLYFPGARIVFTACSHAAVDSLCVKAATAYSSDRCSRIIPQKARIECYDGFKSNNTS 5391
Query 5677 EQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLL 5736
QY+F TVNALPE ADI V DE+SM TNYDLSV+N R+ +H VY+GDP QLPAPR ++
Sbjct 5392 AQYLFSTVNALPEVNADICVVDEVSMCTNYDLSVINQRVNYRHIVYVGDPQQLPAPRVMI 5451
Query 5737 TKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCF 5796
T+G L PE +N V R M + PD+FL C RCPAEIV+TVS +VY+N+ K +S +CF
Sbjct 5452 TRGVLVPEDYNVVTRRMCVLKPDIFLHKCYRCPAEIVNTVSEMVYENQFVPVKSESKECF 5511
Query 5797 KMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQT 5856
K++ +G + D S+INR Q+ VVR FL +NP W KAVFISPYNSQN VA ++LGL QT
Sbjct 5512 KIYCRGNVQVDNGSSINRRQLEVVRMFLAKNPKWAKAVFISPYNSQNYVAGRVLGLQIQT 5571
Query 5857 VDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEI 5916
VDSSQGSEYDYVI+TQT++TAH+ NVNRFNVAITRAK GILCIM DR+L+D L+F L++
Sbjct 5572 VDSSQGSEYDYVIYTQTSDTAHASNVNRFNVAITRAKKGILCIMCDRELFDILKFYELKL 5631
Query 5917 PRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTE-GLCVDIPGIPKDMT 5975
+ LQ + GLFKDC K L P+ APT +S+ FKT+ L V I G+ +
Sbjct 5632 -----SDLQVGDGCGLFKDCYKGEDNLPPSHAPTFMSLSDNFKTDKDLAVQI-GVNGPVK 5685
Query 5976 YRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLG 6035
Y +IS MGF+ + V +F TR+ A+R+ R W+GFDVEG H VGTN+PLQLG
Sbjct 5686 YEHVISFMGFRFDINVPNQHTLFCTRDFAMRNARGWLGFDVEGAHVIGSNVGTNVPLQLG 5745
Query 6036 FSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQML 6095
FS GV+ V P G V T V A+ PPGDQF HL+PL+ KG PW+V+R +IVQM
Sbjct 5746 FSNGVDFVVRPEGCVSTEVGDVIQPVRARAPPGDQFTHLLPLLRKGQPWSVIRRRIVQMC 5805
Query 6096 SDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHS 6155
SD L NLSD ++FVLW+ G ELT+M+YFVK+GP +T C C +RATC+++ + T++C+ H+
Sbjct 5806 SDYLANLSDTLIFVLWSGGLELTTMRYFVKLGPVQT-CDCGKRATCYNSTNHTFSCFRHA 5864
Query 6156 IGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRV 6215
+G DY+YN + ID+QQWG+TG+L NH C +H N HVAS DA MTRCLA+H+CFVK V
Sbjct 5865 LGSDYIYNCYCIDIQQWGYTGSLSMNHHEVCNIHRNEHVASGDAAMTRCLAIHDCFVKNV 5924
Query 6216 DWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKF 6275
DW+I YP I +E IN + R VQ V++A L +HD+GNPK I+CV D W
Sbjct 5925 DWSITYPFIANEQAINKSGRLVQSHVMRAVLKLYNPKAIHDVGNPKGIRCV-VTDASWYC 5983
Query 6276 YDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLN 6335
YD P + +E Y Y TH DG+CLFWNCNVD YP S+VCRFDTR+ S LN
Sbjct 5984 YDKNPTNTNVKMLE---YDYITHGQ--LDGLCLFWNCNVDMYPEFSVVCRFDTRMRSTLN 6038
Query 6336 LPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKS 6395
L GC+GGSLYVN HAFHTPA+DK AF LK +PFF+Y DS CE ++ ++YVPL++
Sbjct 6039 LEGCNGGSLYVNNHAFHTPAYDKRAFAKLKAMPFFFYDDSECE----KLQDAVNYVPLRA 6094
Query 6396 ATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF--TRLQS 6453
+ CITRCN+GGAVC H Y Y+ AYN +AGF++WV FD +NLW TF + +Q
Sbjct 6095 SNCITRCNVGGAVCSKHCALYHNYVMAYNTFTTAGFTIWVPNSFDMFNLWQTFKNSNVQG 6154
Query 6454 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGV-DVELFENKTTLPVNVAFELWAK 6512
LEN+A+NVV KG F G +GE+PV+++N+ V + DGV D +F N T+LP NVAFEL+AK
Sbjct 6155 LENIAYNVVKKGSFVGVEGELPVAVVNDKVMVR-DGVSDNVVFVNNTSLPTNVAFELYAK 6213
Query 6513 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 6572
R + P + IL NLGV + V+WDY+ P T VC TD +
Sbjct 6214 RKVGLTPPLTILKNLGVVCTSKCVLWDYEASRPLTTFTKDVCKYTDFD--------GDVC 6265
Query 6573 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNY-Y 6631
FD V G + F +N VLI+ +VK L ++ LNGV + K Y Y
Sbjct 6266 TLFDNSVPGAFERFTVTKNAVLISLTAVKKLT-AIKLTYGYLNGVPVFTHEDKPFTWYIY 6324
Query 6632 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 6691
+ DG + P+ YFTQ R + +F+PRS ME DFL + M FI +Y LE Y FEH+V+GD
Sbjct 6325 TRKDGAFVEYPDGYFTQGRVISDFQPRSNMEEDFLNMDMGLFISKYGLEDYGFEHVVFGD 6384
Query 6692 FSHSQLGGLHLLIGLAKRFKESPFELEDFI-PMDSTVKNYFITDAQTGSSKCVCSVIDLL 6750
S + LGGLHLLI + K ++EDF+ DST+K+ +T SSK VC+ +DLL
Sbjct 6385 VSKTTLGGLHLLISQIRLSKIGVLKVEDFVSSSDSTLKSCTVTYVDNPSSKMVCTYVDLL 6444
Query 6751 LDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMP 6810
LDDFV I+KS DLSVVSKV +V ID +MLWCKD V+TFYP+LQS++ W+ G +MP
Sbjct 6445 LDDFVNILKSVDLSVVSKVHEVVIDCKVWRWMLWCKDHKVQTFYPQLQSAE-WKCGYSMP 6503
Query 6811 NLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGA 6870
++YK+QRM LE C+L NYG LP GIM NV KYTQLCQYLN+ T+ VP++MRV+H GA
Sbjct 6504 SIYKIQRMCLEPCNLYNYGSGLKLPDGIMFNVVKYTQLCQYLNSTTMCVPHHMRVLHLGA 6563
Query 6871 GSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY 6930
GSDKGVAPGTAVLR+WLP ++VD+D+ND+VSDAD + GDCA+++ +K+DL+ISDMY
Sbjct 6564 GSDKGVAPGTAVLRRWLPLDAVIVDNDVNDYVSDADFSYTGDCASMYLTDKFDLVISDMY 6623
Query 6931 DPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTA 6990
D +TK+ +N SKEGFF YI G I +KLALGG+VAIKITE SWN LY+L+ F +WT
Sbjct 6624 DGRTKSCDGDNVSKEGFFPYINGVITEKLALGGTVAIKITEFSWNKKLYELIQKFEYWTL 6683
Query 6991 FVTNVNASSSEAFLIGCNYLG--KPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKF 7048
F T+VN SSSEAFLIG ++LG IDG +MHANYIFWRN+ + +S S+ D+SKF
Sbjct 6684 FCTSVNTSSSEAFLIGVHFLGDFSTNAIIDGNIMHANYIFWRNSTIMTMSYNSVLDLSKF 6743
Query 7049 PLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVNN 7096
K + T V++LK+ + D++L LL G+L+IR N V S+ LVN+
Sbjct 6744 SCKHKATVVVNLKDSSVTDLVLGLLKNGKLLIRNNGVVCGFSNHLVNS 6791
Score = 75.5 bits (184), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 65/204 (32%), Positives = 94/204 (46%), Gaps = 16/204 (8%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLH 1116
VVNAAN L HGGG+A AL+ T +QV S+ Y++ NG +KVG ++ L+
Sbjct 1323 VVNAANEQLSHGGGIAKALDDLTKGELQVLSNQYVSRNGSIKVGSGVLIKCKE--HSILN 1380
Query 1117 VVGPNVNKGEDIQLLKSAYE-NFNQHEVLLAPLLSAGIFGADPIHSLR---VCVDTVRTN 1172
VVGP K +LL AY F Q V L PLLS GIF SL CV
Sbjct 1381 VVGPRKGK-HAAELLTKAYTFVFKQKGVPLMPLLSVGIFKVPITESLAAFLACVGDRVCK 1439
Query 1173 VYLAVFDKNL-YDKLVSSFLEMKSEKQVE-----QKIAEIPKEEVKPFITESKPSVEQRK 1226
+ + L V+SF ++E+ VE Q++ + E+ P + P R
Sbjct 1440 CFCYTDKERLAIQNFVTSF---QTEQPVEPLPVIQEVKGVQLEKPVPDVKVENPCEPFRI 1496
Query 1227 QDDKKIKACVEEVTTTLEETKFLT 1250
+ D K + +L+ T+ ++
Sbjct 1497 EGDAKFYDLTPSMVQSLQVTRLVS 1520
Score = 61.6 bits (148), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 54/206 (26%), Positives = 87/206 (42%), Gaps = 12/206 (6%)
Query 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
+L E + ++V T D + HT + S TYGQQ G ++ VT +KP + + + V
Sbjct 1634 TLFEAKPVQVVVTQDQRSFHTVELSTSQTYGQQLGDCVVEDKKVTNLKPVSKDKVVS--V 1691
Query 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTK-KWKYPQVNGLTSIKWADNNCYLATA 1679
+PN V+ ++Y D L+HT + VNG ++ +DNNC++
Sbjct 1692 VPN-----VDWDKHYGFVDAGIF----HTLDHTMFVFDNNVVNGKRVLRTSDNNCWINAV 1742
Query 1680 LLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHA 1739
L LQ KF P LQ + G+ A F + GE D T++ + +
Sbjct 1743 CLQLQFANAKFKPKGLQQLWESYCTGDVAMFVHWLYWITGVEKGEPSDAENTLNIISRFL 1802
Query 1740 NLDSCKRVLNVVCKTCGQQQTTLKGV 1765
+L TC +T + V
Sbjct 1803 KPQGSVEMLRATSTTCDGTCSTKRVV 1828
>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729
Score = 4306 bits (11167), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2299/4891 (47%), Positives = 3093/4891 (63%), Gaps = 220/4891 (4%)
Query 2263 CTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISS-FKWDLTAF 2321
C GY ST YC S+ C +CL + + I L F
Sbjct 1999 CGDIVSGYEKST-FNKDIYCGNSMVCKMCLFSYQEFNDLDHTSLVWKHIRDPILISLQPF 2057
Query 2322 GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMV 2381
++ + ++ RF + +A + F S+ H W + P +
Sbjct 2058 VILVILLIFGNMYLRFGLLYFVAQFISTFGSFLGFH--QKQWFL-------HFVPFDVLC 2108
Query 2382 RMYIFFASFYYVWKSYV---HVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYA 2438
F A+F V K + H++ GCN++ C+ C K R RV TI+NG+ +SFYV A
Sbjct 2109 NE--FLATFI-VCKIVLFVRHIIVGCNNADCVACSKSARLKRVPLQTIINGMHKSFYVNA 2165
Query 2439 NGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKN 2498
NGG FC HN+ CVNCD+F G+TFI+ ++AR+L K + PT + I+D V N
Sbjct 2166 NGGTCFCNKHNFFCVNCDSFGPGNTFINGDIARELGNVVKTAVQPTAPAYVIIDKVDFVN 2225
Query 2499 GSIHLY---------FDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKC 2549
G LY FD K + L + L+N N GS N+
Sbjct 2226 GFYRLYSGDTFWRYDFDITESKYSCKEVLKNCNVLENFIVYNNSGS---NI--------- 2273
Query 2550 EESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKL 2609
+ K+A VY+SQL+C+PI L++ L+S + S + + AYV+ ++F
Sbjct 2274 --TQIKNACVYFSQLLCEPIKLVNSELLSTL--SVDFNGVLHKAYVDVLCNSF------- 2322
Query 2610 KTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDS 2669
EL N+S+ +T G SD D V + +H+ D+ ++ S
Sbjct 2323 -------FKELTANMSMAECKATL------GLTVSD---DDFVSAVANAHRYDVLLSDLS 2366
Query 2670 CNNYMLTYNKVEN-MTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQ 2728
NN+ ++Y K E+ ++ D+ C+ ++ +N V +I ++W VKDF +LS++ +K
Sbjct 2367 FNNFFISYAKPEDKLSVYDIACCMRAGSKVVNHNVLIKESIPIVWGVKDFNTLSQEGKKY 2426
Query 2729 IRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGG---KIVNNWLKQLIKVTLVFLFVAA 2785
+ K L F LT + + V T I K G K N+L V LFV A
Sbjct 2427 LVKTTKAKGLTFLLTFNDNQAITQVPATSIVAKQGAGFKRTYNFL------WYVCLFVVA 2480
Query 2786 IFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSY 2845
+F ++ + + T F +K I+ G + + C N +F+ W + G
Sbjct 2481 LFIGVSFIDYTTTVTSFHG--YDFKYIENGQLKVFEAPLHCVRNVFDNFNQWHEAKFGVV 2538
Query 2846 T-NDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHF-LPRVFSAVGNICYTPSKLI 2903
T N CP++ V R VVPG+P + G L F L F G +CY
Sbjct 2539 TTNSDKCPIVVGVSERIN--VVPGVPTNVYLV--GKTLVFTLQAAFGNTG-VCY------ 2587
Query 2904 EYTDFATS-ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSII 2962
++ TS C+ + CT + G V YCY+T+++EGS Y +L+P+ Y + +
Sbjct 2588 DFDGVTTSDKCIFNSACTRLEGLGGDNV-YCYNTDLIEGSKPYSTLQPNAYYKYDAKNYV 2646
Query 2963 QFPNTYLEG-SVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGV 3021
+FP G +R + T + YCR G C S GVC +W +N+ R G CG
Sbjct 2647 RFPEILARGFGLRTIRTLATRYCRVGECRDSHKGVCFGFD-KWYVNDG--RVDDGYICGD 2703
Query 3022 DAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFN 3081
++LL N+ + + +S ++ + A +T L + +F+R FG+ S+ V
Sbjct 2704 GLIDLLVNVLSIFSSSFSVVAMSGHMLFNFLFAAFITFLCFLVTKFKRVFGDLSYGV--- 2760
Query 3082 TLLFLMSFTVLCLTPVYS---------FLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMF 3132
FTV+C T + + F +Y++ LY F T +++ HI ++V +
Sbjct 2761 -------FTVVCATLINNISYVVTQNLFFMLLYAI--LYFVFTRTVRYAWIWHIAYIVAY 2811
Query 3133 TPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFNGVSF-STFEEAALCTFLLNKE 3188
L+P+W+ + S F N K ++ +F G F TFE AA TF+L+
Sbjct 2812 FLLIPWWLLTWF----SFAAFLELLPNVFKLKISTQLFEGDKFIGTFESAAAGTFVLDMR 2867
Query 3189 MYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDV 3248
Y +L + + + Y A YNKYKY+SG+ YR A HLAKA+ D++ +D+
Sbjct 2868 SYERLINTI--SPEKLKNYAASYNKYKYYSGSASEADYRCACYAHLAKAMLDYAKDHNDM 2925
Query 3249 LYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICT 3308
LY PP S S LQSG +KMA PSG VE C+V+V G+T LNG+WL D V CPRHVI
Sbjct 2926 LYSPPTISYNST-LQSGLKKMAQPSGCVERCVVRVCYGSTVLNGVWLGDTVTCPRHVIAP 2984
Query 3309 SEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVR 3368
S +L +Y+ HNF V V L V+G +M VL++KV +N TPK+ F
Sbjct 2985 STTVL-IDYDHAYSTMRLHNFSVSHNGVFLGVVGVTMHGSVLRIKVSQSNVHTPKHVFKT 3043
Query 3369 IQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYD-CVSFCYMHH 3427
++PG +F++LACY G SGV+ +R NFTIKGSF+NG+CGS G+N+ D V FCY+H
Sbjct 3044 LKPGDSFNILACYEGIASGVFGVNLRTNFTIKGSFINGACGSPGYNVRNDGTVEFCYLHQ 3103
Query 3428 MELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFT 3487
+EL +G H G+D G+ YG F D+ + Q + ++ NV+A+LYAA++NG RW+L
Sbjct 3104 IELGSGAHVGSDFTGSVYGNFDDQPSLQVESANLMLSDNVVAFLYAALLNGCRWWLCSTR 3163
Query 3488 TTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGS 3547
++ FN AM Y ++ V+ L+A+TG++V + AS++ L G G+ ILG
Sbjct 3164 VNVDGFNEWAMANGYTSVSS--VECYSILAAKTGVSVEQLLASIQHL-HEGFGGKNILGY 3220
Query 3548 ALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLY 3607
+ L DEFT +VV+Q GV QS + I G L ++ ++ W+ F +Y
Sbjct 3221 SSLCDEFTLAEVVKQMYGVNLQSG--KVIFGLKTMFLFSVFFTMF-------WAELF-IY 3270
Query 3608 ENA-------FLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
N P ++ +S MF+KHK FL +FLLP++ A +N V ++
Sbjct 3271 TNTIWINPVILTPIFCLLLFLSLVLTMFLKHKFLFLQVFLLPTVIATALYNCVL--DYYI 3328
Query 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
++ + + S+ ++ V + ++ L T R + + +++ + Y
Sbjct 3329 VKFLADHFNYNVSVLQMDVQGLVNVLVCLFVVFLHTWRFSKERFTHWFTYVCSLIAVAYT 3388
Query 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
+Y + M+ IS + Y G + V L+R IVF E +F + G+ ++ +
Sbjct 3389 YFYSGDFLSLLVMFLCAIS-SDWYIGAI--VFRLSRLIVFFSPE--SVFSVFGD-VKLTL 3442
Query 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
+VY GY Y+G+ NR+F+ T+GVYD+ VS EF+YM + GL P DA L
Sbjct 3443 VVYLICGYLVCTYWGILYWFNRFFKCTMGVYDFKVSAAEFKYMVANGLHAPHGPFDALWL 3502
Query 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
+ KLLG+GG CIK++TVQSK++D+KCT+VVLL L + + ++S WA CV LHN I L
Sbjct 3503 SFKLLGIGGDRCIKISTVQSKLTDLKCTNVVLLGCLSSMNIAANSSEWAYCVDLHNKINL 3562
Query 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
D +A +++LL+ LS ++ L + DN +TLQ++AS F S+PSY A+ A
Sbjct 3563 CDDPEKAQSMLLALLAFFLSKHSDFGLDGLIDSYFDNSSTLQSVASSFVSMPSYIAYENA 3622
Query 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
++AYE A+ANG S ++K+LK+++N+AKSEFD + ++Q+K+ +MA+QA TQMYK+ARS +
Sbjct 3623 RQAYEDAIANGSSSQLIKQLKRAMNIAKSEFDHEISVQKKINRMAEQAATQMYKEARSVN 3682
Query 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
+++KV SAM ++LF MLR+LD ++ ++N ARDG VPL++IP T+A+KL +V PD +Y
Sbjct 3683 RKSKVISAMHSLLFGMLRRLDMSSVETVLNLARDGVVPLSVIPATSASKLTIVSPDLESY 3742
Query 4081 -KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKL 4139
K CDG+ YA +W + V D D + V + EI+ +N L WPLI+ R VKL
Sbjct 3743 SKIVCDGSVH-YAGVVWTLNDVKDNDGRPVHVKEITKENVETLTWPLILNCERV---VKL 3798
Query 4140 QNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKS 4199
QNNE+ P L+Q A D NAL YNT G F+ A +S+ DLK+ ++
Sbjct 3799 QNNEIMPGKLKQKPMKAEGDGGVLGDGNAL--YNTEGGKTFMYAYISNKADLKFVKWEYE 3856
Query 4200 DGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATE 4259
G TI EL+ PCRF+ +TP GP+VKYLYF+K LN L RG VLG + AT+RLQAG TE
Sbjct 3857 GGCNTI--ELDSPCRFMVETPNGPQVKYLYFVKNLNTLRRGAVLGFIGATIRLQAGKQTE 3914
Query 4260 VPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQE 4319
+ NS +L+ CAF+VD A Y + + G +P++NC+KML G GQAIT + +AN +Q+
Sbjct 3915 LAVNSGLLTACAFSVDPATTYLEAVKHGAKPVSNCIKMLSNGAGNGQAITTSVDANTNQD 3974
Query 4320 SFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGY 4379
S+GGAS CLYCR H+ HP+ G+C KGK VQ+P C DP+ F L+N VC VCG W G+
Sbjct 3975 SYGGASICLYCRAHVPHPSMDGYCKFKGKCVQVPIGCL-DPIRFCLENNVCNVCGCWLGH 4033
Query 4380 GCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAK 4439
GC+CD+ +QS D S+LNR G SAARL PC GT D RAFDIYN V+ K
Sbjct 4034 GCACDR---TTIQSVDI-SYLNRARGSSAARLEPC-NGTDIDKCVRAFDIYNKNVSFLGK 4088
Query 4440 FLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRID 4499
LK NC RF+ D L D YFV+KR T S +HE+++YNLL A+A+HDFF ++ D
Sbjct 4089 CLKMNCVRFKNAD----LKDGYFVIKRCTKSVMEHEQSMYNLLNFSGALAEHDFFTWK-D 4143
Query 4500 GDMV-PHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFV 4558
G ++ ++SR LTKYTM DLVYA+R+FDE NCD LKE+LV CCD+ YF+ K WYD V
Sbjct 4144 GRVIYGNVSRHNLTKYTMMDLVYAMRNFDEQNCDVLKEVLVLTGCCDNSYFDSKGWYDPV 4203
Query 4559 ENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTT 4618
EN DI RVYA+LG+ V +A+LK V CDAM G+VGVLTLDNQDLNGN+YDFGDF+ +
Sbjct 4204 ENEDIHRVYASLGKIVARAMLKCVALCDAMVAKGVVGVLTLDNQDLNGNFYDFGDFVVSL 4263
Query 4619 PGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIK-WDLLKYDFTEERLKLFDR 4677
P GVP SYYS +MPI+ LT L +E V +D+ K +DLLKYDFTE + LF++
Sbjct 4264 PNMGVPCCTSYYSYMMPIMGLTNCLASECFVKSDIFGSDFKTFDLLKYDFTEHKENLFNK 4323
Query 4678 YFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTG 4737
YFK+W YHPNC +C DD C++HCANFN LF+T P T+FGPL RK+F+DGVP V + G
Sbjct 4324 YFKHWSFDYHPNCSDCYDDMCVIHCANFNTLFATTIPGTAFGPLCRKVFIDGVPLVTTAG 4383
Query 4738 YHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNV 4797
YHF++LG+V N+DVN HS RL+ ELL + DP++ AS L+D+RT CFSVAAL+ +
Sbjct 4384 YHFKQLGLVWNKDVNTHSVRLTITELLQFVTDPSLIIASSPALVDQRTICFSVAALSTGL 4443
Query 4798 AFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCD 4857
Q VKPG+FN++FY+F +GFF EGS + LKHFFFAQ+G+AA+ D+D+YRYN PT+ D
Sbjct 4444 TNQVVKPGHFNEEFYNFLRLRGFFDEGSELTLKHFFFAQNGDAAVKDFDFYRYNKPTILD 4503
Query 4858 IRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQD 4917
I Q ++V +YFD Y+GGCI A +V+V NL+KSAG+P NK+GKA LYY+S+SYE+QD
Sbjct 4504 ICQARVTYKIVSRYFDIYEGGCIKACEVVVTNLNKSAGWPLNKFGKASLYYESISYEEQD 4563
Query 4918 ALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGA 4977
ALFA TKRNV+PT+TQ+NLKYAIS K RARTV GVS+ STMT RQ+HQK LKSI TR A
Sbjct 4564 ALFALTKRNVLPTMTQLNLKYAISGKERARTVGGVSLLSTMTTRQYHQKHLKSIVNTRNA 4623
Query 4978 TVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTC 5037
TVVIGT+KFYGGW+NML+T+ VENP LMGWDYPKCDRA+PNM+R+++++VL KH C
Sbjct 4624 TVVIGTTKFYGGWNNMLRTLIDGVENPMLMGWDYPKCDRALPNMIRMISAMVLGSKHVNC 4683
Query 5038 CSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVN 5097
C+ + RFYRL NE AQVL+E+V G Y KPGGT+SGDA+TAYANS+FNI QAV++N+N
Sbjct 4684 CTATDRFYRLGNELAQVLTEVVYSNGGFYFKPGGTTSGDASTAYANSIFNIFQAVSSNIN 4743
Query 5098 ALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVC 5157
LLS + + VR+LQ RLY+ YR V+ F++++Y YLRKHFSMMILSDD VVC
Sbjct 4744 RLLSVPSDSCNNVNVRDLQRRLYDNCYRLTSVEESFIDDYYGYLRKHFSMMILSDDGVVC 4803
Query 5158 FNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDD 5217
+N YA G +A I FK+ LYYQNNVFMS +KCW E DLTKGPHEFCSQHTM + D
Sbjct 4804 YNKDYAELGYIADISAFKATLYYQNNVFMSTSKCWVEEDLTKGPHEFCSQHTMQIVDKDG 4863
Query 5218 YVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYL 5277
YLPYPDPSRIL AG FVDD+VKTD +++ER+VSLAIDAYPL+KHPN EY VF++ L
Sbjct 4864 TYYLPYPDPSRILSAGVFVDDVVKTDAVVLLERYVSLAIDAYPLSKHPNSEYRKVFYVLL 4923
Query 5278 QYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTS 5337
+++ L+ L +L+ +SV L ++ ++W +FY +MY T+LQA G CV+C SQT
Sbjct 4924 DWVKHLNKNLNEGVLESFSVTLLDNQEDKFWCEDFYASMYENSTILQAAGLCVVCGSQTV 4983
Query 5338 LRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCK 5397
LRCG C+R+P LC KC YDHV T HK +L++ PYVCNA GC V+DV +LYLGG++YYC
Sbjct 4984 LRCGDCLRKPMLCTKCAYDHVFGTDHKFILAITPYVCNASGCGVSDVKKLYLGGLNYYCT 5043
Query 5398 SHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLF 5457
+HKP +SFPLC+ G +FGLYKN+ GS +V FN +AT DWT+ DY LAN + L+LF
Sbjct 5044 NHKPQLSFPLCSAGNIFGLYKNSATGSLDVEVFNRLATSDWTDVRDYKLANDVKDTLRLF 5103
Query 5458 AAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKV 5517
AAET+KA EE+ K SY AT++EV+ +EL LSWE GK +PPLNRN VFT ++++K+SK
Sbjct 5104 AAETIKAKEESVKSSYAFATLKEVVGPKELLLSWESGKVKPPLNRNSVFTCFQISKDSKF 5163
Query 5518 QIGEYTFEKGDYG-DAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGL 5576
QIGE+ FEK +YG D V Y+ T T KL G FVLTSH V PL APT+ QE Y I L
Sbjct 5164 QIGEFIFEKVEYGSDTVTYKSTVTTKLVPGMIFVLTSHNVQPLRAPTIANQEKYSSIYKL 5223
Query 5577 YPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHA 5636
+P N+SD +++ V YQ +G QK +T+QGPPG+GKSH +IGL LYYP ARIV+ AC+HA
Sbjct 5224 HPAFNVSDAYANLVPYYQLIGKQKITTIQGPPGSGKSHCSIGLGLYYPGARIVFVACAHA 5283
Query 5637 AVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVV 5696
AVD+LC KA+ IDKC+RIIPARARVEC+ FK N+T QY+F TVNALPE ADIVV
Sbjct 5284 AVDSLCAKAMTVYSIDKCTRIIPARARVECYSGFKPNNTSAQYIFSTVNALPECNADIVV 5343
Query 5697 FDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTI 5756
DE+SM TNYDLSV+N RL KH VY+GDP QLPAPR ++TKG +EP +N V + M I
Sbjct 5344 VDEVSMCTNYDLSVINQRLSYKHIVYVGDPQQLPAPRVMITKGVMEPVDYNVVTQRMCAI 5403
Query 5757 GPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQ 5816
GPD+FL C RCPAEIV+TVS LVY+NK K S QCFK+F+KG + D S+INR Q
Sbjct 5404 GPDVFLHKCYRCPAEIVNTVSELVYENKFVPVKPASKQCFKVFFKGNVQVDNGSSINRKQ 5463
Query 5817 IGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTET 5876
+ +V+ FL +NP+W KAVFISPYNSQN VAS+ LGL QTVDSSQGSEYDYVI+ QT++T
Sbjct 5464 LEIVKLFLVKNPSWSKAVFISPYNSQNYVASRFLGLQIQTVDSSQGSEYDYVIYAQTSDT 5523
Query 5877 AHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDC 5936
AH+CNVNRFNVAITRAK GI C+M D+ L+D L+F EI A L + V GLFK+C
Sbjct 5524 AHACNVNRFNVAITRAKKGIFCVMCDKTLFDSLKF--FEIKH---ADLHSSQVCGLFKNC 5578
Query 5937 SKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYP 5995
++ L PT A T LS+ +FKT G L V I G TY +IS MGF+ + + G
Sbjct 5579 TRTPLNLPPTHAHTFLSLSDQFKTTGDLAVQI-GSNNVCTYEHVISFMGFRFDISIPGSH 5637
Query 5996 NMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNN 6055
++F TR+ AIR+VR W+G DVE H + +GTN+PLQ+GFS GVN V G V T
Sbjct 5638 SLFCTRDFAIRNVRGWLGMDVESAHVCGDNIGTNVPLQVGFSNGVNFVVQTEGCVSTNFG 5697
Query 6056 TDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGF 6115
V AK PPG+QF+HLIPL+ KG PW +VR +IVQM+SD L NLSD +VFVLWA
Sbjct 5698 DVIKPVCAKSPPGEQFRHLIPLLRKGQPWLIVRRRIVQMISDYLSNLSDILVFVLWAGSL 5757
Query 6116 ELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFT 6175
ELT+M+YFVKIGP + C C ATC+++ S+ Y C+ H++G DYVYNP+ D+QQWG+
Sbjct 5758 ELTTMRYFVKIGPIKY-CYCGNSATCYNSVSNEYCCFKHALGCDYVYNPYAFDIQQWGYV 5816
Query 6176 GNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACR 6235
G+L NH +C +H N H AS DA+MTRCLAVH+CFVK VDWT+ YP I +E IN R
Sbjct 5817 GSLSQNHHTFCNIHRNEHDASGDAVMTRCLAVHDCFVKNVDWTVTYPFIANEKFINGCGR 5876
Query 6236 KVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSY 6295
VQ VV+AAL K V+HDIGNPK ++C D +W YD QP + ++ L Y Y
Sbjct 5877 NVQGHVVRAALKLYKPSVIHDIGNPKGVRCA-VTDAKWYCYDKQPVNS---NVKLLDYDY 5932
Query 6296 ATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPA 6355
ATH DG+CLFWNCNVD YP SIVCRFDTR S NL G +GGSLYVNKHAFHTPA
Sbjct 5933 ATHGQ--LDGLCLFWNCNVDMYPEFSIVCRFDTRTRSVFNLEGVNGGSLYVNKHAFHTPA 5990
Query 6356 FDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANE 6415
+DK AFV LK +PFFY+ DS C+ +QV +YVPL++++C+TRCN+GGAVC HAN
Sbjct 5991 YDKRAFVKLKPMPFFYFDDSDCDVVQEQV----NYVPLRASSCVTRCNIGGAVCSKHANL 6046
Query 6416 YRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF--TRLQSLENVAFNVVNKGHFDGQQGE 6473
Y+ Y++AYN AGF++WV FD YNLW F T LQSLEN+AFNVV KG F G GE
Sbjct 6047 YQKYVEAYNTFTQAGFNIWVPHSFDVYNLWQIFIETNLQSLENIAFNVVKKGCFTGVDGE 6106
Query 6474 VPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAA 6533
+PV+++N+ V+ + VD +F NKTTLP NVAFEL+AKR + P + IL NLGV
Sbjct 6107 LPVAVVNDKVFVRYGDVDNLVFTNKTTLPTNVAFELFAKRKMGLTPPLSILKNLGVVATY 6166
Query 6534 NTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGV 6593
V+WDY+ + P T VC TD E +C V FD + G + F N V
Sbjct 6167 KFVLWDYEAERPFTSYTKSVCKYTDF----NEDVC----VCFDNSIQGSYERFTLTTNAV 6218
Query 6594 LITEGSVKGLQPSVGPKQASLNGVTLIG----EAVKTQFNYYKKV--DGVVQQLPETYFT 6647
L + +K L P + LNG+ + + V+ N+Y V +G Q + ++T
Sbjct 6219 LFSTVVIKNLTP-IKLNFGMLNGMPVSSIKGDKGVEKLVNWYIYVRKNGQFQDHYDGFYT 6277
Query 6648 QSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLA 6707
Q RNL +F PRS ME DFL + M FI +Y LE + FEH+VYGD S + LGGLHLLI
Sbjct 6278 QGRNLSDFTPRSDMEYDFLNMDMGVFINKYGLEDFNFEHVVYGDVSKTTLGGLHLLISQF 6337
Query 6708 KRFKESPFELEDFIPM-DSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVV 6766
+ K + +DF+ D+T++ +T SSK VC+ +DLLLDDFV I+KS DL V+
Sbjct 6338 RLSKMGVLKADDFVTASDTTLRCCTVTYLNELSSKVVCTYMDLLLDDFVTILKSLDLGVI 6397
Query 6767 SKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQ 6826
SKV +V ID +MLWCKD H+ TFYP+LQS++ W+ G AMP +YK+QRM LE C+L
Sbjct 6398 SKVHEVIIDNKPYRWMLWCKDNHLSTFYPQLQSAE-WKCGYAMPQIYKLQRMCLEPCNLY 6456
Query 6827 NYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQW 6886
NYG LP GIM+NV KYTQLCQYLN+ T+ VP+NMRV+H+GAGSDKGVAPGT VL++W
Sbjct 6457 NYGAGIKLPSGIMLNVVKYTQLCQYLNSTTMCVPHNMRVLHYGAGSDKGVAPGTTVLKRW 6516
Query 6887 LPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEG 6946
LP +++D+D+ND+VSDAD ++ GDCATV+ +K+DL+ISDMYD + K EN SK+G
Sbjct 6517 LPPDAIIIDNDINDYVSDADFSITGDCATVYLEDKFDLLISDMYDGRIKFCDGENVSKDG 6576
Query 6947 FFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIG 7006
FFTY+ G I++KLA+GGSVAIKITE+SWN LY+L+ FA+WT F T+VN SSSEAFLIG
Sbjct 6577 FFTYLNGVIREKLAIGGSVAIKITEYSWNKYLYELIQRFAFWTLFCTSVNTSSSEAFLIG 6636
Query 7007 CNYLGKPREQ--IDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQ 7064
NYLG + I G +HANYIFWRN+ + LS S+ D+SKF K + T V++LK+
Sbjct 6637 INYLGDFIQGPFIAGNTVHANYIFWRNSTIMSLSYNSVLDLSKFECKHKATVVVTLKDSD 6696
Query 7065 INDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
+NDM+LSL+ GRL++R N R S+ LV+
Sbjct 6697 VNDMVLSLIKSGRLLLRNNGRFGGFSNHLVS 6727
Score = 80.9 bits (198), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 55/144 (38%), Positives = 74/144 (51%), Gaps = 6/144 (4%)
Query 1020 VQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKAT 1079
++ EV F+ Y NV DI V VVNAAN L HGGGVA A++ T
Sbjct 1252 IEAGEVKPFAVY----KNVKFYLGDISHLVNCVSFDFVVNAANENLLHGGGVARAIDILT 1307
Query 1080 NNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFN 1139
+Q S DYI++NGPLKVG +L + +VVGP K E L+++
Sbjct 1308 EGQLQSLSKDYISSNGPLKVGAGVMLECEKF--NVFNVVGPRTGKHEHSLLVEAYNSILF 1365
Query 1140 QHEVLLAPLLSAGIFGADPIHSLR 1163
++ + L PLLS GIFG +SL+
Sbjct 1366 ENGIPLMPLLSCGIFGVRIENSLK 1389
Score = 51.2 bits (121), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 50/174 (29%), Positives = 72/174 (41%), Gaps = 16/174 (9%)
Query 1573 TVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLP-NDDTLRVEA 1631
T D IN+ VV+ S + G+Q G DG D S EG VLP N DT+ A
Sbjct 1587 TEDGINVKDVVVESSKSLGKQLGVVS-DGVD--------SFEG----VLPINTDTVLSVA 1633
Query 1632 FEYYHTTDPSFLGRYMSALNHTKKWKYPQ--VNGLTSIKWADNNCYLATALLTLQQIELK 1689
E F + A K + YP V G + DNNC++ + LQ ++
Sbjct 1634 PEVDWVAFYGFEKAALFASLDVKPYGYPNDFVGGFRVLGTTDNNCWVNATCIILQYLKPT 1693
Query 1690 FNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDS 1743
F L + + G+ F + I + G+ GD E +S L ++ DS
Sbjct 1694 FKSKGLNVLWNKFVTGDVGPFVSFIYFITMSSKGQKGDAEEALSKLSEYLISDS 1747
Score = 38.5 bits (88), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 42/176 (24%), Positives = 72/176 (41%), Gaps = 13/176 (7%)
Query 1663 GLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV 1722
G+ + +DNNC+++T L+ LQ +L + +Q + G+ + +
Sbjct 1051 GVRVLDQSDNNCWISTTLVQLQLTKLLDDSIEMQ----LFKVGKVDSIVQKCYELSHLIS 1106
Query 1723 GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKG 1782
G LGD + +S L + +C + C CG++ G ++ + F+KG
Sbjct 1107 GSLGDSGKLLSELLKEKY--TCSITFEMSCD-CGKKFDDQVG---CLFWIMPYTKLFQKG 1160
Query 1783 VQIPCTCGKQATKYLVQQESPFVMMSAP-PAQYELKHGTFTCASEYTGNYQCGHYK 1837
C C K T LV + V + P P + C+S Y G GHY+
Sbjct 1161 E--CCICHKMQTYKLVSMKGTGVFVQDPAPIDIDAFPVKPICSSVYLGVKGSGHYQ 1214
>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781
Score = 4290 bits (11126), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2276/4910 (46%), Positives = 3101/4910 (63%), Gaps = 195/4910 (4%)
Query 2230 IIWFLLLS-VCLG-SLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIP 2287
+ WF +L LG +Y+ + + + +G P C GY NS+ YC S+
Sbjct 2020 LYWFKVLGKFSLGIYALYALLFMTIRFTPIGSP-VCDDVVAGYANSS-FDKNEYCN-SVI 2076
Query 2288 CSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIM 2347
C VCL G L + + + W L+ FFY+ LA
Sbjct 2077 CKVCLYGYQELSDFSHTQVV--------WQHLRDPLIGN-------VMPFFYLAFLAIFG 2121
Query 2348 QLFFSYFAVHFIS---NSWLMWL----IINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
++ ++FI NS ++L I +Q+ P + F V HV
Sbjct 2122 GVYVKAITLYFIFQYLNSLGVFLGLQQSIWFLQLVPFDVFGDEIVVFFIVTRVLMFIKHV 2181
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GC+ ++C+ C K R RV TI G +SFYV+ANGG FCK HN+ C+NCD++
Sbjct 2182 CLGCDKASCVACSKSARLKRVPVQTIFQGTSKSFYVHANGGSKFCKKHNFFCLNCDSYGP 2241
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G TFI+D +A ++ K + PT ++ ++D V NG +LY K + S
Sbjct 2242 GCTFINDVIATEVGNVVKLNVQPTGPATILIDKVEFSNGFYYLYSGDTFWKYNFDITDSK 2301
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
+ + L+ S+ + IVF+ + K+A VY+SQ++C+P+ L+D AL++ +
Sbjct 2302 YTCKEALK----NCSIITDFIVFNNNGS-NVNQVKNACVYFSQMLCKPVKLVDSALLASL 2356
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNV-LSTFISAARQ 2639
S + + A+V+ S++F + + + + D+V L TF +A +
Sbjct 2357 --SVDFGASLHSAFVSVLSNSFGKDLSSCNDM-----QDCKSTLGFDDVPLDTFNAAVAE 2409
Query 2640 GFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTP-RDLGACIDCSARH 2698
+H+ D+ +T S NN+ +Y K E P D+ C+ A+
Sbjct 2410 ------------------AHRYDVLLTDMSFNNFTTSYAKPEEKFPVHDIATCMRVGAKI 2451
Query 2699 INAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKI 2758
+N V +I ++W V+DF++LSE+ RK I K + F LT R + T I
Sbjct 2452 VNHNVLVKDSIPVVWLVRDFIALSEETRKYIIRTTKVKGITFMLTFNDCRMHTTIPTVCI 2511
Query 2759 ALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEI-----IGYKAID 2813
A K G + ++ K + LF+ A F+ ++ DFS+++ +K I+
Sbjct 2512 ANKKGAGLPSFSKVKKFFWFLCLFIVAAFFALS-------FLDFSTQVSSDSDYDFKYIE 2564
Query 2814 GGVTRDIASTDTCFANKHADFDTWFSQRGG-SYTNDKACPLIAAVITREVGFVVPGLPGT 2872
G + + +C N +FD W + G + N+ +CP++ V + VPG+P
Sbjct 2565 SGQLKTFDNPLSCVHNVFINFDQWHDAKFGFTPVNNPSCPIVVGV--SDEARTVPGIPAG 2622
Query 2873 ILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPY 2932
+ G L F +C+ S + + AC+ + CT G V Y
Sbjct 2623 VYLA--GKTLVFAINTIFGTSGLCFDASGVAD-----KGACIFNSACTTLSGLGGTAV-Y 2674
Query 2933 CYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCER 2991
CY ++EG+ Y L P + Y ++DG+ + P G +R + T YCR G C +
Sbjct 2675 CYKNGLVEGAKLYSELAPHSYYKMVDGNAVSLPEIISRGFGIRTIRTKAMTYCRVGQCVQ 2734
Query 2992 SEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGG 3051
S GVC +V N + S CG LL N+ + + + +S I+
Sbjct 2735 SAEGVCFGADRFFVYNAE---SGSDFVCGTGLFTLLMNVISVFSKTVPVTVLSGQILFNC 2791
Query 3052 IVAIVVTCLAYYFMRFRRAFGEYS---HVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVI 3108
I+A V + + F +F+R FG+ S V TLL +S+ V T + +
Sbjct 2792 IIAFVAVAVCFLFTKFKRMFGDMSVGVFTVGACTLLNNVSYIVTQNT--------LGMLG 2843
Query 3109 YLYLTFYLTNDVSFLA--HIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV- 3165
Y L F T V ++ H+ +++ + + P+W+ + Y + + F N K +V
Sbjct 2844 YATLYFLCTKGVRYMWIWHLGFLISYILIAPWWVLMVY----AFSAIFEFMPNLFKLKVS 2899
Query 3166 --VFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMD 3222
+F G F +FE AA TF+L+ Y +L + + + +Y + YNKYKY+SG+
Sbjct 2900 TQLFEGDKFVGSFENAAAGTFVLDMHAYERLANSI--STEKLRQYASTYNKYKYYSGSAS 2957
Query 3223 TTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQ 3282
YR A HLAKA+ D++++ +D LY PP S S LQ+G RKMA PSG VE C+V+
Sbjct 2958 EADYRLACFAHLAKAMMDYASNHNDTLYTPPTVSYNST-LQAGLRKMAQPSGVVEKCIVR 3016
Query 3283 VTCGTTTLNGLWLDDVVYCPRHVICTSE-DMLNPNYEDLLIRKSNHNFLVQAGNVQLRVI 3341
V G LNGLWL D+V CPRHVI +S ++ +Y ++R HNF + +GNV L V+
Sbjct 3017 VCYGNMALNGLWLGDIVMCPRHVIASSTTSTIDYDYALSVLRL--HNFSISSGNVFLGVV 3074
Query 3342 GHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKG 3401
+M+ +L++KV+ N TPKY + ++PG++F++LACY+G+ +GVY MR N+TI+G
Sbjct 3075 SATMRGALLQIKVNQNNVHTPKYTYRTVRPGESFNILACYDGAAAGVYGVNMRSNYTIRG 3134
Query 3402 SFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDT 3461
SF+NG+CGS G+NI+ V FCY+H +EL +G H G+DL+G YG + D+ T Q G +
Sbjct 3135 SFINGACGSPGYNINNGTVEFCYLHQLELGSGCHVGSDLDGVMYGGYEDQPTLQVEGASS 3194
Query 3462 TITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTG 3521
T NVLA+LYAA+ING W+L+ ++ FN A+ T + D L+A+TG
Sbjct 3195 LFTENVLAFLYAALINGSTWWLSSSRIAVDRFNEWAVHNGMT--TVGNTDCFSILAAKTG 3252
Query 3522 IAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSA-VKRTIKGTH 3580
+ V + AS++ L +N G+ ILG L DEFT +VVRQ GV Q V R +
Sbjct 3253 VDVQRLLASIQSLHKN-FGGKQILGHTSLTDEFTTGEVVRQMYGVNLQGGYVSRACRN-- 3309
Query 3581 HWLLLTILTSLLVLVQS--TQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCL 3638
+ ++ S L S ++ FF++ P + +S+ M +KHK F +
Sbjct 3310 ----VLLVGSFLTFFWSELVSYTKFFWVNPGYVTPMFACLSLLSSLLMFTLKHKTLFFQV 3365
Query 3639 FLLPSLATVAYFNMVYMPASWVMRIMTWL-DMVD--TSLSGFKLKDCVMYASAVVLLILM 3695
FL+P+L + N+ + + + +L + D SL GF + V V+ IL
Sbjct 3366 FLIPALIVTSCINLAFD-----VEVYNYLAEHFDYHVSLMGFNAQGLVNIFVCFVVTILH 3420
Query 3696 TART--VYDDGARRVWTLMNVLTLVYKVYYG-NALDQAISMWALIISVTSNYSGVVTTVM 3752
T ++ A V ++ +LT Y +Y + L A++++A SVT N+ V V
Sbjct 3421 GTYTWRFFNTPASSVTYVVALLTAAYNYFYASDILSCAMTLFA---SVTGNW--FVGAVC 3475
Query 3753 FLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYD 3812
+ + V+M + + P F ++ +M Y LGYF C++G+ NR+F++++GVYD
Sbjct 3476 Y--KVAVYMALRF-PTFVAIFGDIKSVMFCYLVLGYFTCCFYGILYWFNRFFKVSVGVYD 3532
Query 3813 YLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVL 3872
Y VS EF+YM + GL P ++D+ L+ KL+G+GG+ IK+++VQSK++D+KC++VVL
Sbjct 3533 YTVSAAEFKYMVANGLRAPTGTLDSLLLSAKLIGIGGERNIKISSVQSKLTDIKCSNVVL 3592
Query 3873 LSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCE 3932
L L + V ++S WA CV LHN I L D +A E +++LL+ LS A ++ L E
Sbjct 3593 LGCLSSMNVSANSTEWAYCVDLHNKINLCNDPEKAQEMLLALLAFFLSKNSAFGLDDLLE 3652
Query 3933 EMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFD 3992
++ + LQ++AS + LPSY + A++ YE AV NG ++K+L+ ++NVAKSEFD
Sbjct 3653 SYFNDNSMLQSVASTYVGLPSYVIYENARQQYEDAVNNGSPPQLVKQLRHAMNVAKSEFD 3712
Query 3993 RDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNA 4052
R+A+ QRKL++MA+QA QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I+N A
Sbjct 3713 REASTQRKLDRMAEQAAAQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNLA 3772
Query 4053 RDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLS 4112
+DG VPL++IP +A KL +V D ++Y YA +W I + D D K+V +
Sbjct 3773 KDGVVPLSVIPAVSATKLNIVTSDIDSYNRIQREGCVHYAGTIWNIIDIKDNDGKVVHVK 3832
Query 4113 EISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYY 4172
E++ N+ +L+WPL++ R VKLQNNE+ P L+Q S A A Y
Sbjct 3833 EVTAQNAESLSWPLVLGCERI---VKLQNNEIIPGKLKQRSIKAEGDGIV---GEGKALY 3886
Query 4173 NTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIK 4232
N G F+ A +SD DL+ ++ G TI ELEPP +F+ D+P G ++KYLYF++
Sbjct 3887 NNEGGRTFMYAFISDKPDLRVVKWEFDGGCNTI--ELEPPRKFLVDSPNGAQIKYLYFVR 3944
Query 4233 GLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPIT 4292
LN L RG VLG + ATVRLQAG TE NS++L+ CAFAVD AK Y D + SG +P+
Sbjct 3945 NLNTLRRGAVLGYIGATVRLQAGKQTEQAINSSLLTLCAFAVDPAKTYIDAVKSGHKPVG 4004
Query 4293 NCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQI 4352
NCVKML +G GQA+T EA+ +Q+S+GGAS CLYCR H++HP+ GFC LKGKYVQ+
Sbjct 4005 NCVKMLANGSGNGQAVTNGVEASTNQDSYGGASVCLYCRAHVEHPSMDGFCRLKGKYVQV 4064
Query 4353 PTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLT 4412
P DP+ F L+N VC VCG W GC+CD+ ++QS D ++LNRV G SAARL
Sbjct 4065 PLGTV-DPIRFVLENDVCKVCGCWLSNGCTCDR---SIMQSTD-MAYLNRVRGSSAARLE 4119
Query 4413 PCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNY 4472
PC GT T VYRAFDIYN VA KFLK NC R + D+ D +++VVKR T S
Sbjct 4120 PC-NGTDTQHVYRAFDIYNKDVACLGKFLKVNCVRLKNLDKHD----AFYVVKRCTKSAM 4174
Query 4473 QHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCD 4532
+HE++IY+ L+ C A+A+HDFF ++ + ++ R+ LT+YTM DL YALR+FDE NCD
Sbjct 4175 EHEQSIYSRLEKCGAIAEHDFFTWKDGRAIYGNVCRKDLTEYTMMDLCYALRNFDENNCD 4234
Query 4533 TLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAG 4592
LK IL+ C++ YFN K W+D VEN DI RVYA LG V +A+LK V+FCDAM G
Sbjct 4235 VLKSILIKVGACEESYFNNKVWFDPVENEDIHRVYALLGTIVARAMLKCVKFCDAMVEQG 4294
Query 4593 IVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTD 4652
IVGV+TLDNQDLNG++YDFGDF + G GVP+ SYYS +MP++ +T L +E V +D
Sbjct 4295 IVGVVTLDNQDLNGDFYDFGDFTCSIKGMGVPICTSYYSYMMPVMGMTNCLASECFVKSD 4354
Query 4653 L-TKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFST 4711
+ + + +DLL+YDFTE + LF++YFKYW YHPNCV+C D++CI+HCANFN LFST
Sbjct 4355 IFGEDFKSYDLLEYDFTEHKTALFNKYFKYWGLQYHPNCVDCSDEQCIVHCANFNTLFST 4414
Query 4712 VFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPA 4771
P T+FGPL RK ++DGVP V + GYHF++LG+V N D+NLHSSRLS ELL + +DPA
Sbjct 4415 TIPITAFGPLCRKCWIDGVPLVTTAGYHFKQLGIVWNNDLNLHSSRLSINELLQFCSDPA 4474
Query 4772 MHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKH 4831
+ AS L+D+RT CFSVAAL + QTVKPG+FNK+FYDF + +GFF EGS + LKH
Sbjct 4475 LLIASSPALVDQRTVCFSVAALGTGMTNQTVKPGHFNKEFYDFLLEQGFFSEGSELTLKH 4534
Query 4832 FFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLD 4891
FFFAQ +AA+ D+DYYRYN PT+ DI Q V ++V +YFD Y+GGCI A +V+V NL+
Sbjct 4535 FFFAQKVDAAVKDFDYYRYNRPTVLDICQARVVYQIVQRYFDIYEGGCITAKEVVVTNLN 4594
Query 4892 KSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAG 4951
KSAG+P NK+GKA LYY+S+SYE+QD L+AYTKRN++PT+TQ+NLKYAIS K RARTV G
Sbjct 4595 KSAGYPLNKFGKAGLYYESLSYEEQDELYAYTKRNILPTMTQLNLKYAISGKERARTVGG 4654
Query 4952 VSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDY 5011
VS+ STMT RQ+HQK LKSI TRGA+VVIGT+KFYGGW NMLK + VENP LMGWDY
Sbjct 4655 VSLLSTMTTRQYHQKHLKSIVNTRGASVVIGTTKFYGGWDNMLKNLIDGVENPCLMGWDY 4714
Query 5012 PKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGG 5071
PKCDRA+PNM+R++++++L KHTTCCS + RF+RL NE AQVL+E+V G Y+KPGG
Sbjct 4715 PKCDRALPNMIRMISAMILGSKHTTCCSSTDRFFRLCNELAQVLTEVVYSNGGFYLKPGG 4774
Query 5072 TSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDT 5131
T+SGDATTAYANSVFNI QAV+ANVN LLS D N + V+ LQ +LYEC YR+ VD
Sbjct 4775 TTSGDATTAYANSVFNIFQAVSANVNKLLSVDSNVCHNLEVKQLQRKLYECCYRSTIVDD 4834
Query 5132 DFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKC 5191
FV E+Y YLRKHFSMMILSDD VVC+N+ YAS G VA + FK+VLYYQNNVFMS +KC
Sbjct 4835 QFVVEYYGYLRKHFSMMILSDDGVVCYNNDYASLGYVADLNAFKAVLYYQNNVFMSASKC 4894
Query 5192 WTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERF 5251
W E D+ KGPHEFCSQHTM + + YLPYPDPSRIL AG FVDD+VKTD +++ER+
Sbjct 4895 WIEPDINKGPHEFCSQHTMQIVDKEGTYYLPYPDPSRILSAGVFVDDVVKTDAVVLLERY 4954
Query 5252 VSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPE 5311
VSLAIDAYPL+KH N EY VF++ L +++ L+ L +L+ +SV L D+T+++W+
Sbjct 4955 VSLAIDAYPLSKHENPEYKKVFYVLLDWVKHLYKTLNAGVLESFSVTLLEDSTAKFWDES 5014
Query 5312 FYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNP 5371
FY MY VLQ+ G CV+C SQT LRCG C+RRP LC KC YDHVI T+HK +L++ P
Sbjct 5015 FYANMYEKSAVLQSAGLCVVCGSQTVLRCGDCLRRPMLCTKCAYDHVIGTTHKFILAITP 5074
Query 5372 YVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFN 5431
YVC A C V DVT+LYLGG+SY+C HKP ++FPLC+ G VFGLYKN+ GS +V DFN
Sbjct 5075 YVCCASDCGVNDVTKLYLGGLSYWCHEHKPRLAFPLCSAGNVFGLYKNSATGSPDVEDFN 5134
Query 5432 AIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSW 5491
IAT DWT+ DY LAN + L+LFAAET+KA EE+ K SY AT+ EV+ +EL L W
Sbjct 5135 RIATSDWTDVSDYRLANDVKDSLRLFAAETIKAKEESVKSSYACATLHEVVGPKELLLKW 5194
Query 5492 EVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDY-GDAVVYRGTTTYKLNVGDYFV 5550
EVG+P+PPLNRN VFT Y +TKN+K QIGE+ FEK +Y DAV Y+ T T KL G FV
Sbjct 5195 EVGRPKPPLNRNSVFTCYHITKNTKFQIGEFVFEKAEYDNDAVTYKTTATTKLVPGMVFV 5254
Query 5551 LTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGT 5610
LTSH V PL APT+ QE Y I L+P NI + +SS V YQ +G QK +T+QGPPG+
Sbjct 5255 LTSHNVQPLRAPTIANQERYSTIHKLHPAFNIPEAYSSLVPYYQLIGKQKITTIQGPPGS 5314
Query 5611 GKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKF 5670
GKSH IGL LYYP ARIV+TACSHAAVD+LC KA DKCSRIIP RARVEC+D F
Sbjct 5315 GKSHCVIGLGLYYPGARIVFTACSHAAVDSLCVKASTAYSNDKCSRIIPQRARVECYDGF 5374
Query 5671 KVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLP 5730
K N+T QY+F TVNALPE ADIVV DE+SM TNYDLSV+N R+ +H VY+GDP QLP
Sbjct 5375 KSNNTSAQYLFSTVNALPECNADIVVVDEVSMCTNYDLSVINQRISYRHVVYVGDPQQLP 5434
Query 5731 APRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD 5790
APR ++++GTLEP+ +N V + M + PD+FL C RCPAEIV TVS +VY+N+
Sbjct 5435 APRVMISRGTLEPKDYNVVTQRMCALKPDVFLHKCYRCPAEIVRTVSEMVYENQFIPVHP 5494
Query 5791 KSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKIL 5850
S QCFK+F KG + D S+INR Q+ VVR FL +NP W KAVFISPYNSQN VAS++L
Sbjct 5495 DSKQCFKIFCKGNVQVDNGSSINRRQLDVVRMFLAKNPRWSKAVFISPYNSQNYVASRLL 5554
Query 5851 GLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQ 5910
GL QTVDSSQGSEYDYVI+ QT++TAH+ NVNRFNVAITRAK GILCIM DR L+D L+
Sbjct 5555 GLQIQTVDSSQGSEYDYVIYAQTSDTAHASNVNRFNVAITRAKKGILCIMCDRSLFDLLK 5614
Query 5911 FTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGI 5970
F L++ + LQA GLFKDCS+ L P+ A T +S+ FKT+ G+
Sbjct 5615 FFELKL-----SDLQANEGCGLFKDCSRGDDLLPPSHANTFMSLADNFKTDQYLAVQIGV 5669
Query 5971 PKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNL 6030
+ Y +IS MGF+ + + + +F TR+ A+R+VR W+GFDVEG H VGTN+
Sbjct 5670 NGPIKYEHVISFMGFRFDINIPNHHTLFCTRDFAMRNVRGWLGFDVEGAHVVGSNVGTNV 5729
Query 6031 PLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIK 6090
PLQLGFS GV+ V P G V T + V A+ PPG+QF HL+PL+ +G PW+VVR +
Sbjct 5730 PLQLGFSNGVDFVVRPEGCVVTESGDYIKPVRARAPPGEQFAHLLPLLKRGQPWDVVRKR 5789
Query 6091 IVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYA 6150
IVQM SD L NLSD ++FVLWA G ELT+M+YFVKIGP ++ C C + ATC+++A TY
Sbjct 5790 IVQMCSDYLANLSDILIFVLWAGGLELTTMRYFVKIGPSKS-CDCGKVATCYNSALHTYC 5848
Query 6151 CWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHEC 6210
C+ H++G DY+YNP+ ID+QQWG+ G+L NH +C VH N HVAS DAIMTRCLA+H+C
Sbjct 5849 CFKHALGCDYLYNPYCIDIQQWGYKGSLSLNHHEHCNVHRNEHVASGDAIMTRCLAIHDC 5908
Query 6211 FVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQAD 6270
FVK VDW+I YP IG+E IN + R VQ +++ L ++DIGNPK I+C D
Sbjct 5909 FVKNVDWSITYPFIGNEAVINKSGRIVQSHTMRSVLKLYNPKAIYDIGNPKGIRCA-VTD 5967
Query 6271 VEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRV 6330
+W +D P + +E Y Y TH DG+CLFWNCNVD YP S+VCRFDTR
Sbjct 5968 AKWFCFDKNPTNSNVKTLE---YDYITHGQ--FDGLCLFWNCNVDMYPEFSVVCRFDTRC 6022
Query 6331 LSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDY 6390
S LNL GC+GGSLYVN HAFHTPAFDK AF LK +PFF+Y D+ C+ ++ I+Y
Sbjct 6023 RSPLNLEGCNGGSLYVNNHAFHTPAFDKRAFAKLKPMPFFFYDDTECD----KLQDSINY 6078
Query 6391 VPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFT- 6449
VPL+++ CIT+CN+GGAVC H Y Y++AYN SAGF++WV FDTYNLW TF+
Sbjct 6079 VPLRASNCITKCNVGGAVCSKHCAMYHSYVNAYNTFTSAGFTIWVPTSFDTYNLWQTFSN 6138
Query 6450 RLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFEL 6509
LQ LEN+AFNV+ KG F G +GE+PV+++N+ V + VD +F NKT+LP NVAFEL
Sbjct 6139 NLQGLENIAFNVLKKGSFVGDEGELPVAVVNDKVLVRDGTVDTLVFTNKTSLPTNVAFEL 6198
Query 6510 WAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICA 6569
+AKR + P + IL NLGV + VIWDY+ + P T VC TD
Sbjct 6199 YAKRKVGLTPPITILRNLGVVCTSKCVIWDYEAERPLTTFTKDVCKYTDFE--------G 6250
Query 6570 PLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL-IGEAVKTQF 6628
+ FD + G ++ F +N VL++ +VK L + LNGV + E +
Sbjct 6251 DVCTLFDNSIVGSLERFSMTQNAVLMSLTAVKKLT-GIKLTYGYLNGVPVNTHEDKPFTW 6309
Query 6629 NYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIV 6688
Y + +G + P+ YFTQ R +F PRS ME DFL + M FI +Y LE Y FEH+V
Sbjct 6310 YIYTRKNGKFEDYPDGYFTQGRTTADFSPRSDMEKDFLSMDMGLFINKYGLEDYGFEHVV 6369
Query 6689 YGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPM-DSTVKNYFITDAQTGSSKCVCSVI 6747
YGD S + LGGLHLLI + ++++F+ DST+K+ +T A SSK VC+ +
Sbjct 6370 YGDVSKTTLGGLHLLISQVRLACMGVLKIDEFVSSNDSTLKSCTVTYADNPSSKMVCTYM 6429
Query 6748 DLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGV 6807
DLLLDDFV I+KS DLSVVSKV +V +D +MLWCKD ++TFYP+LQ+S+ W+ G
Sbjct 6430 DLLLDDFVSILKSLDLSVVSKVHEVMVDCKMWRWMLWCKDHKLQTFYPQLQASE-WKCGY 6488
Query 6808 AMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIH 6867
+MP++YK+QRM LE C+L NYG LP GIM NV KYTQLCQYLN+ T+ VP++MRV+H
Sbjct 6489 SMPSIYKIQRMCLEPCNLYNYGAGVKLPDGIMFNVVKYTQLCQYLNSTTMCVPHHMRVLH 6548
Query 6868 FGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIIS 6927
GAGSDKGVAPGTAVLR+WLP ++VD+D D+VSDAD ++ GDC+T++ ++K+DL+IS
Sbjct 6549 LGAGSDKGVAPGTAVLRRWLPLDAIIVDNDSVDYVSDADYSVTGDCSTLYLSDKFDLVIS 6608
Query 6928 DMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAW 6987
DMYD K K+ EN SKEGFF YI G I +KLALGG+VAIK+TE SWN LY+L+ F +
Sbjct 6609 DMYDGKIKSCDGENVSKEGFFPYINGVITEKLALGGTVAIKVTEFSWNKKLYELIQKFEY 6668
Query 6988 WTAFVTNVNASSSEAFLIGCNYLG--KPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDM 7045
WT F T+VN SSSEAFLIG +YLG IDG MHANYIFWRN+ + +S S+ D+
Sbjct 6669 WTMFCTSVNTSSSEAFLIGVHYLGDFASGAVIDGNTMHANYIFWRNSTIMTMSYNSVLDL 6728
Query 7046 SKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
SKF K + T V++LK+ I+D++L LL G+L++R N+ + S+ LVN
Sbjct 6729 SKFNCKHKATVVVNLKDSSISDVVLGLLKNGKLLVRNNDAICGFSNHLVN 6778
Score = 71.2 bits (173), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 58/173 (34%), Positives = 76/173 (44%), Gaps = 10/173 (6%)
Query 993 GSEDNQTTTIQTIVEVQPQLEMELTPVVQTIE---VNSFSGYLKLTDNVYIKNADIVEEA 1049
G + T+ TI L P V ++ V F Y NV D +
Sbjct 1255 GRHQIKYDTLNTICVKDVNWTAPLVPAVDSVVEPVVKPFYSY----KNVDFYQGDF-SDL 1309
Query 1050 KKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHN 1109
K+ VVNAAN L HGGG+A A++ T +Q S+DYI +GP+KVG +L
Sbjct 1310 VKLPCDFVVNAANEKLSHGGGIAKAIDVYTKGMLQKCSNDYIKAHGPIKVGRGVMLEA-- 1367
Query 1110 LAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSL 1162
L +VVGP K L+K+ F V L PL+S GIF SL
Sbjct 1368 LGLKVFNVVGPRKGKHAPELLVKAYKSVFANSGVALTPLISVGIFSVPLEESL 1420
Score = 48.9 bits (115), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 85/344 (25%), Positives = 138/344 (40%), Gaps = 38/344 (11%)
Query 1548 GEVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKI 1607
G V T D+++ + + V IKV T D ++ V+ + TYGQQ GP ++ VT
Sbjct 1616 GFVSTPDDVERFYANKSV-VIKV--TEDTRSVKAVKVESTATYGQQIGPCLVNDTVVTDN 1672
Query 1608 KPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQ--VNGLT 1665
KP + V+PN + ++ ++ D + G + L+HT + +P VNG
Sbjct 1673 KPVVADVVAK--VVPNAN------WDSHYGFDKA--GEF-HMLDHTG-FTFPSEVVNGRR 1720
Query 1666 SIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGEL 1725
IK DNNC++ L LQ +F LQ + G+ A F + G+
Sbjct 1721 VIKTTDNNCWVNVTCLQLQFARFRFKSAGLQAMWESYCTGDVAMFVHWLYWLTGVDKGQP 1780
Query 1726 GDVRETMSYLFQH---ANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKG 1782
D ++ L ++ A + +RV + C C ++ T V A + K G
Sbjct 1781 SDSENALNMLSKYIVPAGSVTIERVTHDGC-CCSKRVVTAPVVNASV---------LKLG 1830
Query 1783 VQ---IPCTCGKQATKYLVQQESPFVMMSAP---PAQYELKHGTFTCASEYTGNYQCGHY 1836
V+ P +V+ + V + P P+ LK ++T + GN GHY
Sbjct 1831 VEDGLCPHGLNYIGKVVVVKGTTIVVNVGKPVVAPSHLFLKGVSYTTFLD-NGNGVVGHY 1889
Query 1837 KHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPV 1880
+ T DG P+T+V E + PV
Sbjct 1890 T-VFDHGTGMVHDGDAFVPGDLNVSPVTNVVVSEQTAVVIKDPV 1932
>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus
229E OX=11137 GN=rep PE=1 SV=1
Length=6758
Score = 4258 bits (11044), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2277/4991 (46%), Positives = 3133/4991 (63%), Gaps = 237/4991 (5%)
Query 2172 FFTLLLQLCTFTRST----NSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLI 2227
FFT LL + T ++ + +I A P +S+ K+ L+AS LKS
Sbjct 1936 FFTWLLSMFTLCKTAVTTGDVKIMAKAPQRTGVVLKRSL-KYNLKASAAVLKSK------ 1988
Query 2228 NIIIWFLLLSVC-LGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSI 2286
W+LL L LIY+ ++ +L G ++C+ GY S N YC GS+
Sbjct 1989 ----WWLLAKFTKLLLLIYTLYSVVLLCVRFGPFNFCSETVNGYAKS-NFVKDDYCDGSL 2043
Query 2287 PCSVCLSGLDSLDTYPSLETI--QITISSFKWDLTAFGLVAEWFL---AYILFTRFFYVL 2341
C +CL G L + L+ + IT F ++ F ++ + Y+ ++V
Sbjct 2044 GCKMCLFGYQELSQFSHLDVVWKHITDPLFS-NMQPFIVMVLLLIFGDNYLRCFLLYFVA 2102
Query 2342 GLAAIMQLFFSY----FAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY 2397
+ + + +F Y + +HFI + ++ V + + + VR
Sbjct 2103 QMISTVGVFLGYKETNWFLHFIPFDVICDELLVTVIVIKVISFVR--------------- 2147
Query 2398 VHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDT 2457
HV+ GC + C+ C K R R TIVNGV+RSFYV ANGG FCK H + CV+CD+
Sbjct 2148 -HVLFGCENPDCIACSKSARLKRFPVNTIVNGVQRSFYVNANGGSKFCKKHRFFCVDCDS 2206
Query 2458 FCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLY---------FDKA 2508
+ GSTFI+ EV+R+L K + PT + ++D V +NG LY FD
Sbjct 2207 YGYGSTFITPEVSRELGNITKTNVQPTGPAYVMIDKVEFENGFYRLYSCETFWRYNFDIT 2266
Query 2509 GQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQP 2568
K + + LD+ N G+ NV + K+ASVY+SQL+C+P
Sbjct 2267 ESKYSCKEVFKNCNVLDDFIVFNNNGT---NV-----------TQVKNASVYFSQLLCRP 2312
Query 2569 ILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSL-D 2627
I L+D L+S + S + + AY++ ++F + L ++ AE + A +S+ D
Sbjct 2313 IKLVDSELLSTL--SVDFNGVLHKAYIDVLRNSFG---KDLNANMSLAECKRALGLSISD 2367
Query 2628 NVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNK-VENMTPR 2686
+ ++ IS A H+ D+ ++ S NN++ +Y K E ++
Sbjct 2368 HEFTSAISNA---------------------HRCDVLLSDLSFNNFVSSYAKPEEKLSAY 2406
Query 2687 DLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCAT 2746
DL C+ A+ +NA V ++W+ KDF SLS + RK I +K L F LT
Sbjct 2407 DLACCMRAGAKVVNANVLTKDQTPIVWHAKDFNSLSAEGRKYIVKTSKAKGLTFLLTINE 2466
Query 2747 TRQVVNVVTTKIALKGGKIVNN----WLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDF 2802
+ V + T I K G WL L + + F F ++S
Sbjct 2467 NQAVTQIPATSIVAKQGAGDAGHSLTWLWLLCGLVCLIQFYLCFFMPYFMYDIVS----- 2521
Query 2803 SSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTW-FSQRGGSYTNDKACPLIAAVITRE 2861
S E +K I+ G ++ + C N +F+ W +++ G + N ++CP++ V E
Sbjct 2522 SFEGYDFKYIENGQLKNFEAPLKCVRNVFENFEDWHYAKFGFTPLNKQSCPIVVGV--SE 2579
Query 2862 VGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICY------TPSKLIEYTDFATSACVL 2915
+ V G+P + G L F + +CY TP K C+
Sbjct 2580 IVNTVAGIPSNVYLV--GKTLIFTLQAAFGNAGVCYDIFGVTTPEK-----------CIF 2626
Query 2916 AAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEG-SVR 2974
+ CT + G V YCY+T ++EGS+ Y S++ + Y +G+ I+ P +G R
Sbjct 2627 TSACTRLEGLGGNNV-YCYNTALMEGSLPYSSIQANAYYKYDNGNFIKLPEVIAQGFGFR 2685
Query 2975 VVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPL 3034
V T ++YCR G C S AGVC +W +N+ R G CG NL+ N+ +
Sbjct 2686 TVRTIATKYCRVGECVESNAGVCFGFD-KWFVNDG--RVANGYVCGTGLWNLVFNILSMF 2742
Query 3035 IQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCL 3094
+S I+ + + +FRR FG+ S V + L++ +
Sbjct 2743 SSSFSVAAMSGQILLNCALGAFAIFCCFLVTKFRRMFGDLSVGVCTVVVAVLLNNVSYIV 2802
Query 3095 TPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFY 3154
T + Y+++Y + T L +++ +++ + P+W+ Y + + T
Sbjct 2803 TQNLVTMIA-YAILYFFATRSLR--YAWIWCAAYLIAYISFAPWWLCAWYFLAMLTG--- 2856
Query 3155 WFFSNYLKRRV---VFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
+ LK +V +F G F TFE AA TF+++ Y KL + + + Y A
Sbjct 2857 -LLPSLLKLKVSTNLFEGDKFVGTFESAAAGTFVIDMRSYEKLANSI--SPEKLKSYAAS 2913
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMA 3270
YN+YKY+SG + YR A +LAKA+ DFS +D+LY PP S S LQ+G RKMA
Sbjct 2914 YNRYKYYSGNANEADYRCACYAYLAKAMLDFSRDHNDILYTPPTVSYGST-LQAGLRKMA 2972
Query 3271 FPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLIRKSNHNF 3329
PSG VE C+V+V G T LNGLWL D+VYCPRHVI + + ++ ++E ++R HNF
Sbjct 2973 QPSGFVEKCVVRVCYGNTVLNGLWLGDIVYCPRHVIASNTTSAIDYDHEYSIMRL--HNF 3030
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G L V+G +M LK+KV N TP++ F ++ G+ F++LACY+G GV+
Sbjct 3031 SIISGTAFLGVVGATMHGVTLKIKVSQTNMHTPRHSFRTLKSGEGFNILACYDGCAQGVF 3090
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR N+TI+GSF+NG+CGS G+N+ V F YMH +EL +G H G+ +G YG F
Sbjct 3091 GVNMRTNWTIRGSFINGACGSPGYNLKNGEVEFVYMHQIELGSGSHVGSSFDGVMYGGFE 3150
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D+ Q + +TVNV+A+LYAA++NG W+L + +N A + + +
Sbjct 3151 DQPNLQVESANQMLTVNVVAFLYAAILNGCTWWLKGEKLFVEHYNEWAQANGFTAMNGE- 3209
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
D L+A+TG+ V + ++ ++L NG G+ ILG + L DEF+ +VV+Q GV Q
Sbjct 3210 -DAFSILAAKTGVCVERLLHAI-QVLNNGFGGKQILGYSSLNDEFSINEVVKQMFGVNLQ 3267
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYEN-AFL-PFAMGIIAMSAFAMM 3627
S K T + +++ V+ + + ++ N FL PF + ++A+S
Sbjct 3268 SG-----KTTSMFKSISLFAGFFVMFWAELFVYTTTIWVNPGFLTPFMILLVALSLCLTF 3322
Query 3628 FVKHKHAFLCLFLLPSLATVAYFNMVYMPASW---VMRIMTWLDMVDTSLSGFKLKDCVM 3684
VKHK FL +FLLPS+ A N +W V +++ + S+ ++ V
Sbjct 3323 VVKHKVLFLQVFLLPSIIVAAIQN-----CAWDYHVTKVLAEKFDYNVSVMQMDIQGFVN 3377
Query 3685 YASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNY 3744
+ + +L T R + L +++ ++Y Y +S+ +++ SN
Sbjct 3378 IFICLFVALLHTWRFAKERCTHWCTYLFSLIAVLYTALYSY---DYVSLLVMLLCAISNE 3434
Query 3745 SGVVTTVMFLAR-GIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
+ + + R G+ F+ VEY F + ++ ++L Y LG+ Y+GL +NR+
Sbjct 3435 WYIGAIIFRICRFGVAFLPVEYVSYF----DGVKTVLLFYMLLGFVSCMYYGLLYWINRF 3490
Query 3804 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMS 3863
+ TLGVYD+ VS EF+YM + GL P DA L+ KL+G+GG IKV+TVQSK++
Sbjct 3491 CKCTLGVYDFCVSPAEFKYMVANGLNAPNGPFDALFLSFKLMGIGGPRTIKVSTVQSKLT 3550
Query 3864 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3923
D+KCT+VVL+ +L + + S+SK WA CV++HN I L D A E +++LL+ LS
Sbjct 3551 DLKCTNVVLMGILSNMNIASNSKEWAYCVEMHNKINLCDDPETAQELLLALLAFFLSKHS 3610
Query 3924 AVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKS 3983
+ L + +N + LQ++AS F +PS+ A+ TA++ YE AVANG S ++K+LKK+
Sbjct 3611 DFGLGDLVDSYFENDSILQSVASSFVGMPSFVAYETARQEYENAVANGSSPQIIKQLKKA 3670
Query 3984 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4043
+NVAK+EFDR++++Q+K+ +MA+QA MYK+AR+ ++++KV SAM ++LF MLR+LD
Sbjct 3671 MNVAKAEFDRESSVQKKINRMAEQAAAAMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMS 3730
Query 4044 ALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY-KNTCDGTTFTYASALWEIQQVV 4102
+++ I+N AR+G VPL++IP T+AA+L+VV+PD++++ K DG YA +W +Q+V
Sbjct 3731 SVDTILNMARNGVVPLSVIPATSAARLVVVVPDHDSFVKMMVDGFVH-YAGVVWTLQEVK 3789
Query 4103 DADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4162
D D K V L +++ +N L WPLI+T R VKLQNNE+ P ++ +
Sbjct 3790 DNDGKNVHLKDVTKENQEILVWPLILTCERV---VKLQNNEIMPGKMKVKATKGEGDGGI 3846
Query 4163 CTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4222
++ NAL YN G F+ A ++ +K+ ++ G T+ ELEPPCRFV DTP G
Sbjct 3847 TSEGNAL--YNNEGGRAFMYAYVTTKPGMKYVKWEHDSGVVTV--ELEPPCRFVIDTPTG 3902
Query 4223 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKD 4282
P++KYLYF+K LNNL RG VLG + ATVRLQAG TE +NS +L+ C+FAVD A AY D
Sbjct 3903 PQIKYLYFVKNLNNLRRGAVLGYIGATVRLQAGKQTEFVSNSHLLTHCSFAVDPAAAYLD 3962
Query 4283 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4342
+ G +P+ NCVKML +G+GQAIT T ++N Q+++GGAS C+YCR H+ HP GF
Sbjct 3963 AVKQGAKPVGNCVKMLTNGSGSGQAITCTIDSNTTQDTYGGASVCIYCRAHVAHPTMDGF 4022
Query 4343 CDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNR 4402
C KGK+VQ+P NDP+ F L+NTVC VCG W +GC+CD+ +QS D S+LNR
Sbjct 4023 CQYKGKWVQVPIG-TNDPIRFCLENTVCKVCGCWLNHGCTCDR---TAIQSFD-NSYLNR 4077
Query 4403 VCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYF 4462
V G SAARL PC GT D RAFD+YN + K LK+NC RF+ D+DD +++
Sbjct 4078 VRGSSAARLEPC-NGTDIDYCVRAFDVYNKDASFIGKNLKSNCVRFKNVDKDD----AFY 4132
Query 4463 VVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYA 4522
+VKR S HE+++YNLLK C AVAKHDFF + + ++SRQ LTKYTM DL +A
Sbjct 4133 IVKRCIKSVMDHEQSMYNLLKGCNAVAKHDFFTWHEGRTIYGNVSRQDLTKYTMMDLCFA 4192
Query 4523 LRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTV 4582
LR+FDE +C+ KEILV CC DYF K+W+D +EN DI RVYA LG+ V A+LK V
Sbjct 4193 LRNFDEKDCEVFKEILVLTGCCSTDYFEMKNWFDPIENEDIHRVYAALGKVVANAMLKCV 4252
Query 4583 QFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRA 4642
FCD M G+VGVLTLDNQDLNGN+YDFGDF+ PG G+P SYYS +MP++ +T
Sbjct 4253 AFCDEMVLKGVVGVLTLDNQDLNGNFYDFGDFVLCPPGMGIPYCTSYYSYMMPVMGMTNC 4312
Query 4643 LTAESHVDTDL-TKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILH 4701
L +E + +D+ + + +DLLKYDFTE + LF++YFKYW Q YHP+CV+C D+ CILH
Sbjct 4313 LASECFMKSDIFGQDFKTFDLLKYDFTEHKEVLFNKYFKYWGQDYHPDCVDCHDEMCILH 4372
Query 4702 CANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFK 4761
C+NFN LF+T P T+FGPL RK+F+DGVP V + GYHF++LG+V N+DVN HS+RL+
Sbjct 4373 CSNFNTLFATTIPNTAFGPLCRKVFIDGVPVVATAGYHFKQLGLVWNKDVNTHSTRLTIT 4432
Query 4762 ELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFF 4821
ELL + DP + AS L+DKRT CFSVAAL+ + QTVKPG+FNK+FYDF S+GFF
Sbjct 4433 ELLQFVTDPTLIVASSPALVDKRTVCFSVAALSTGLTSQTVKPGHFNKEFYDFLRSQGFF 4492
Query 4822 KEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCIN 4881
EGS + LKHFFF Q G+AAI D+DYYRYN PTM DI Q +V +YFDCY+GGCI
Sbjct 4493 DEGSELTLKHFFFTQKGDAAIKDFDYYRYNRPTMLDIGQARVAYQVAARYFDCYEGGCIT 4552
Query 4882 ANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAIS 4941
+ +V+V NL+KSAG+P NK+GKA LYY+S+SYE+QDA+F+ TKRN++PT+TQ+NLKYAIS
Sbjct 4553 SREVVVTNLNKSAGWPLNKFGKAGLYYESISYEEQDAIFSLTKRNILPTMTQLNLKYAIS 4612
Query 4942 AKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDV 5001
K RARTV GVS+ +TMT RQFHQK LKSI ATR ATVVIGT+KFYGGW NMLK + +DV
Sbjct 4613 GKERARTVGGVSLLATMTTRQFHQKCLKSIVATRNATVVIGTTKFYGGWDNMLKNLMADV 4672
Query 5002 ENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMC 5061
++P LMGWDYPKCDRAMP+M+R++++++L KH TCC+ S +FYRL+NE AQVL+E+V
Sbjct 4673 DDPKLMGWDYPKCDRAMPSMIRMLSAMILGSKHVTCCTASDKFYRLSNELAQVLTEVVYS 4732
Query 5062 GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYE 5121
G Y KPGGT+SGDATTAYANSVFNI QAV++N+N +LS + + + V+ LQ +LY+
Sbjct 4733 NGGFYFKPGGTTSGDATTAYANSVFNIFQAVSSNINCVLSVNSSNCNNFNVKKLQRQLYD 4792
Query 5122 CLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQ 5181
YRN +VD FV++FY YL+KHFSMMILSDD+VVC+N TYA G +A I FK+ LYYQ
Sbjct 4793 NCYRNSNVDESFVDDFYGYLQKHFSMMILSDDSVVCYNKTYAGLGYIADISAFKATLYYQ 4852
Query 5182 NNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVK 5241
N VFMS AKCWTE DL+ GPHEFCSQHTM + + YLPYPDPSRI+ AG FVDDI K
Sbjct 4853 NGVFMSTAKCWTEEDLSIGPHEFCSQHTMQIVDENGKYYLPYPDPSRIISAGVFVDDITK 4912
Query 5242 TDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTN 5301
TD +++ER+VSLAIDAYPL+KHP EY VF+ L +++ L+ L +L+ +SV L +
Sbjct 4913 TDAVILLERYVSLAIDAYPLSKHPKPEYRKVFYALLDWVKHLNKTLNEGVLESFSVTLLD 4972
Query 5302 DNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVIST 5361
++ S++W+ FY +MY TVLQA G CV+C SQT LRCG C+RRP LC KC YDHV T
Sbjct 4973 EHESKFWDESFYASMYEKSTVLQAAGLCVVCGSQTVLRCGDCLRRPMLCTKCAYDHVFGT 5032
Query 5362 SHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTC 5421
HK +L++ PYVCN GC+V DVT+LYLGG++YYC HKP +SFPLC+ G VFGLYK++
Sbjct 5033 DHKFILAITPYVCNTSGCNVNDVTKLYLGGLNYYCVDHKPHLSFPLCSAGNVFGLYKSSA 5092
Query 5422 VGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREV 5481
+GS ++ FN ++T DW++ DY LAN E L+LFAAET+KA EE+ K SY AT++E+
Sbjct 5093 LGSMDIDVFNKLSTSDWSDIRDYKLANDAKESLRLFAAETVKAKEESVKSSYAYATLKEI 5152
Query 5482 LSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYG-DAVVYRGTTT 5540
+ +EL L WE GK +PPLNRN VFT +++TK+SK Q+GE+ FEK DYG D V Y+ T T
Sbjct 5153 VGPKELLLLWESGKAKPPLNRNSVFTCFQITKDSKFQVGEFVFEKVDYGSDTVTYKSTAT 5212
Query 5541 YKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQK 5600
KL G F+LTSH V PL APT+ QE Y I L+P+ N+SD +++ V YQ +G Q+
Sbjct 5213 TKLVPGMLFILTSHNVAPLRAPTMANQEKYSTIYKLHPSFNVSDAYANLVPYYQLIGKQR 5272
Query 5601 YSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPA 5660
+T+QGPPG+GKSH +IG+ +YYP ARIV+TACSHAAVD+LC KA+ +DKC+RIIPA
Sbjct 5273 ITTIQGPPGSGKSHCSIGIGVYYPGARIVFTACSHAAVDSLCAKAVTAYSVDKCTRIIPA 5332
Query 5661 RARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHY 5720
RARVEC+ FK N+ QYVF TVNALPE ADIVV DE+SM TNYDLSV+N R+ KH
Sbjct 5333 RARVECYSGFKPNNNSAQYVFSTVNALPEVNADIVVVDEVSMCTNYDLSVINQRISYKHI 5392
Query 5721 VYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALV 5780
VY+GDP QLPAPR L++KG +EP +N V + M IGPD+FL C RCPAEIV+TVS LV
Sbjct 5393 VYVGDPQQLPAPRVLISKGVMEPIDYNVVTQRMCAIGPDVFLHKCYRCPAEIVNTVSELV 5452
Query 5781 YDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYN 5840
Y+NK K+ S QCFK+F +G + D S+INR Q+ VV+ F+ +N W KAVFISPYN
Sbjct 5453 YENKFVPVKEASKQCFKIFERGSVQVDNGSSINRRQLDVVKRFIHKNSTWSKAVFISPYN 5512
Query 5841 SQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIM 5900
SQN VA+++LGL TQTVDS+QGSEYDYVIF QT++TAH+CN NRFNVAITRAK GI CIM
Sbjct 5513 SQNYVAARLLGLQTQTVDSAQGSEYDYVIFAQTSDTAHACNANRFNVAITRAKKGIFCIM 5572
Query 5901 SDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT 5960
SDR L+D L+F + + LQ+E+ GLFKDC++ L P+ A T+LS+ +FKT
Sbjct 5573 SDRTLFDALKFFEITM-----TDLQSESSCGLFKDCARNPIDLPPSHATTYLSLSDRFKT 5627
Query 5961 EG-LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGC 6019
G L V I G TY +IS MGF+ + + G ++F TR+ A+RHVR W+G DVEG
Sbjct 5628 SGDLAVQI-GNNNVCTYEHVISYMGFRFDVSMPGSHSLFCTRDFAMRHVRGWLGMDVEGA 5686
Query 6020 HATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMY 6079
H T + VGTN+PLQ+GFS GV+ VA P G V T + V A+ PPG+QF H++PL+
Sbjct 5687 HVTGDNVGTNVPLQVGFSNGVDFVAQPEGCVLTNTGSVVKPVRARAPPGEQFTHIVPLLR 5746
Query 6080 KGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRA 6139
KG PW+V+R +IVQM++D L SD +VFVLWA G ELT+M+YFVKIG + C C A
Sbjct 5747 KGQPWSVLRKRIVQMIADFLAGSSDVLVFVLWAGGLELTTMRYFVKIGAVKH-CQCGTVA 5805
Query 6140 TCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDA 6199
TC+++ S+ Y C+ H++G DYVYNP++ID+QQWG+ G+L +NH C VH N HVAS DA
Sbjct 5806 TCYNSVSNDYCCFKHALGCDYVYNPYVIDIQQWGYVGSLSTNHHAICNVHRNEHVASGDA 5865
Query 6200 IMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGN 6259
IMTRCLAV++CFVK VDW+I YP+I +E IN R VQ +++AA+ +HDIGN
Sbjct 5866 IMTRCLAVYDCFVKNVDWSITYPMIANENAINKGGRTVQSHIMRAAIKLYNPKAIHDIGN 5925
Query 6260 PKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPA 6319
PK I+C D +W YD P + +E Y Y TH DG+CLFWNCNVD YP
Sbjct 5926 PKGIRCAV-TDAKWYCYDKNPINSNVKTLE---YDYMTHGQ--MDGLCLFWNCNVDMYPE 5979
Query 6320 NSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCES 6379
SIVCRFDTR S LNL G +GGSLYVN HAFHTPA+DK A LK PFFYY D CE
Sbjct 5980 FSIVCRFDTRTRSTLNLEGVNGGSLYVNNHAFHTPAYDKRAMAKLKPAPFFYYDDGSCE- 6038
Query 6380 HGKQVVSD-IDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQ 6438
VV D ++YVPL++ CIT+CN+GGAVC HAN YR Y+++YN+ AGF++WV
Sbjct 6039 ----VVHDQVNYVPLRATNCITKCNIGGAVCSKHANLYRAYVESYNIFTQAGFNIWVPTT 6094
Query 6439 FDTYNLWNTFTR--LQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFE 6496
FD YNLW TFT LQ LEN+AFNVVNKG F G GE+PV+I + V+ + D +F
Sbjct 6095 FDCYNLWQTFTEVNLQGLENIAFNVVNKGSFVGADGELPVAISGDKVFVRDGNTDNLVFV 6154
Query 6497 NKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSM 6556
NKT+LP N+AFEL+AKR + P + IL NLGV V+WDY+ + P T VC
Sbjct 6155 NKTSLPTNIAFELFAKRKVGLTPPLSILKNLGVVATYKFVLWDYEAERPLTSFTKSVCGY 6214
Query 6557 TDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVK---GLQPSVGPKQAS 6613
TD A E +C +D + G + F + N VL + +VK P++
Sbjct 6215 TDFA----EDVCTC----YDNSIQGSYERFTLSTNAVLFSATAVKTGGKSLPAIKLNFGM 6266
Query 6614 LNGVTLI------GEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLE 6667
LNG + G + Y + DG + ++TQ RNLQ+F PRS ME DFL
Sbjct 6267 LNGNAIATVKSEDGNIKNINWFVYVRKDGKPVDHYDGFYTQGRNLQDFLPRSTMEEDFLN 6326
Query 6668 LAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPM-DST 6726
+ + FI++Y LE + FEH+VYGD S + LGGLHLLI + K + E+F+ D T
Sbjct 6327 MDIGVFIQKYGLEDFNFEHVVYGDVSKTTLGGLHLLISQVRLSKMGILKAEEFVAASDIT 6386
Query 6727 VKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCK 6786
+K +T SSK VC+ +DLLLDDFV ++KS DL+VVSKV +V ID +MLWCK
Sbjct 6387 LKCCTVTYLNDPSSKTVCTYMDLLLDDFVSVLKSLDLTVVSKVHEVIIDNKPWRWMLWCK 6446
Query 6787 DGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYT 6846
D V TFYP+LQS++ W+ G +MP +YK QRM LE C+L NYG LP GIM NV KYT
Sbjct 6447 DNAVATFYPQLQSAE-WKCGYSMPGIYKTQRMCLEPCNLYNYGAGLKLPSGIMFNVVKYT 6505
Query 6847 QLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDAD 6906
QLCQY N+ TL VP+NMRV+H GAGSD GVAPGTAVL++WLP ++VD+D+ D+VSDAD
Sbjct 6506 QLCQYFNSTTLCVPHNMRVLHLGAGSDYGVAPGTAVLKRWLPHDAIVVDNDVVDYVSDAD 6565
Query 6907 STLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVA 6966
++ GDCATV+ +K+DL+ISDMYD +TK + EN SKEGFFTYI GFI +KLA+GGS+A
Sbjct 6566 FSVTGDCATVYLEDKFDLLISDMYDGRTKAIDGENVSKEGFFTYINGFICEKLAIGGSIA 6625
Query 6967 IKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQ--IDGYVMHA 7024
IK+TE+SWN LY+L+ F++WT F T+VN SSSEAF++G NYLG + IDG ++HA
Sbjct 6626 IKVTEYSWNKKLYELVQRFSFWTMFCTSVNTSSSEAFVVGINYLGDFAQGPFIDGNIIHA 6685
Query 7025 NYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENN 7084
NY+FWRN+ + LS S+ D+SKF K + T V+ LK+ IN+M+LSL+ G+L++R N
Sbjct 6686 NYVFWRNSTVMSLSYNSVLDLSKFNCKHKATVVVQLKDSDINEMVLSLVRSGKLLVRGNG 6745
Query 7085 RVVISSDVLVN 7095
+ + S+ LV+
Sbjct 6746 KCLSFSNHLVS 6756
Score = 76.3 bits (186), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 71/245 (29%), Positives = 110/245 (45%), Gaps = 16/245 (7%)
Query 991 QDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYL---KLT-----DNVYIKN 1042
Q + D T + ++E+ +TP+ T++ ++ KL DNV
Sbjct 1226 QPWTNDALNTICIKDADYNAKVEISVTPIKNTVDTTPKEEFVVKEKLNAFLVHDNVAFYQ 1285
Query 1043 ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGS 1102
D+ V +VNAAN L HGGG+A AL+ T +Q S ++I G +KVG
Sbjct 1286 GDVDTVVNGVDFDFIVNAANENLAHGGGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTG 1345
Query 1103 CVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSL 1162
++ +L +VVGP K E L+K+ N+ L P+LS GIFG SL
Sbjct 1346 VMVECDSL--RIFNVVGPRKGKHERDLLIKAYNTINNEQGTPLTPILSCGIFGIKLETSL 1403
Query 1163 RVCVDTVRTN-VYLAVFDKNLYDKL---VSSFLEMKSEKQ--VEQKIAEIPKEEVKPFIT 1216
V +D T V + V+ K+ VS + ++ +Q +E K + K KP+
Sbjct 1404 EVLLDVCNTKEVKVFVYTDTEVCKVKDFVSGLVNVQKVEQPKIEPKPVSVIKVAPKPYRV 1463
Query 1217 ESKPS 1221
+ K S
Sbjct 1464 DGKFS 1468
Score = 55.8 bits (133), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 74/339 (22%), Positives = 137/339 (40%), Gaps = 30/339 (9%)
Query 1560 LSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFY 1619
L E + I + T D +N+H V ++ QQ G D++ P + + +
Sbjct 1595 LKAAEAKVITIKVTEDGVNVHDVTVTTDKSFEQQVGVIADKDKDLSGAVPSDLNTSELL- 1653
Query 1620 VLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTK-KWKYPQVNGLTSIKWADNNCYLAT 1678
+ V+ E+Y D + ++H+ ++ VNG+ +K +DNNC++
Sbjct 1654 ----TKAIDVDWVEFYGFKD----AVTFATVDHSAFAYESAVVNGIRVLKTSDNNCWVNA 1705
Query 1679 ALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQH 1738
+ LQ + F L A+ + G+ F A + G+ GD +T++ L ++
Sbjct 1706 VCIALQYSKPHFISQGLDAAWNKFVLGDVEIFVAFVYYVARLMKGDKGDAEDTLTKLSKY 1765
Query 1739 -ANLDSCKRVLNVVCKTCGQQ-QTTLKGVEAVMYMGTLSYEQFKKGVQIP-CTCGKQATK 1795
AN + C C + + ++ + + + ++ + GVQ+ C G +
Sbjct 1766 LANEAQVQLEHYSSCVECDAKFKNSVASINSAIVCASVK----RDGVQVGYCVHGIKYYS 1821
Query 1796 YLVQQESPFVMMSA----PPAQYELKHGTFTCASEYTGNYQCGHYK-HITSKETLYCIDG 1850
+ +++S P AQ L G A ++G GHY + T+K+++Y DG
Sbjct 1822 RVRSVRGRAIIVSVEQLEPCAQSRLLSGVAYTA--FSGPVDKGHYTVYDTAKKSMY--DG 1877
Query 1851 ALLTKSSEYKGPITDVF----YKENSYTTTIKPVTYKLD 1885
K +T V Y T KPV +LD
Sbjct 1878 DRFVKHDLSLLSVTSVVMVGGYVAPVNTVKPKPVINQLD 1916
Score = 50.1 bits (118), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 62/267 (23%), Positives = 110/267 (41%), Gaps = 18/267 (7%)
Query 1658 YPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAY 1717
+ ++NGL +K DNNC++ + +L +Q + A+Q + R + C
Sbjct 1038 FEELNGLKILKQLDNNCWVNSVMLQIQLTGILDGDYAMQ-FFKMGRVAKMIERC-YTAEQ 1095
Query 1718 CNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYE 1777
C + G +GDV M L + +L + V++ C +C + G AV++ T + +
Sbjct 1096 CIR--GAMGDVGLCMYRLLK--DLHTGFMVMDYKC-SCTSGRLEESG--AVLFC-TPTKK 1147
Query 1778 QFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYK 1837
F G + C + T +Q FV P C+S + G CGHY+
Sbjct 1148 AFPYGTCLNCNAPRMCTIRQLQGTIIFVQQKPEPVNPVSFVVKPVCSSIFRGAVSCGHYQ 1207
Query 1838 HITSKETLYCIDGALLTKSSEYKG-PITDVFYKENSYTT----TIKPVTYKLDGVVCTE- 1891
+ L C+DG + K + + + K+ Y ++ P+ +D E
Sbjct 1208 TNIYSQNL-CVDGFGVNKIQPWTNDALNTICIKDADYNAKVEISVTPIKNTVDTTPKEEF 1266
Query 1892 -IDPKLDNYYKKDNSYFTEQPIDLVPN 1917
+ KL+ + DN F + +D V N
Sbjct 1267 VVKEKLNAFLVHDNVAFYQGDVDTVVN 1293
Score = 38.1 bits (87), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 62/267 (23%), Positives = 106/267 (40%), Gaps = 27/267 (10%)
Query 662 GQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCV 721
G + TCAK K + + N FL ++ IGG K + ++ + +
Sbjct 749 GLLGTCAKRFKRWLGILLEAYNAFLDTVVSTVKIGGLTFKTYAFDKPYIVIRDIVCKVEN 808
Query 722 KSREETGLLMPLKAP-KEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
K+ E L P K E +P T D++ +E +E VE G
Sbjct 809 KTEAEWIELFPHNDRIKSFSTFESAYMPIADPTHF------DIEEVELLDAEFVEPGCGG 862
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDT-VIEVQGYKSV 839
I+ + + KD Y + N++ FT G KV+F DD V +++ V
Sbjct 863 ILAVIDEHVFYK-KDGVYYPSNGTNILPV--AFTKAAGG--KVSFSDDVEVKDIEPVYRV 917
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
+ FE + D+ L + C +G ++ D+ KT+Q + L +
Sbjct 918 KLCFEFE---DEKLVDVCEK---AIGKKIKHEG--DWDSFCKTIQ------SALSVVSCY 963
Query 900 WSMATYYLFDESGEFKLASHMYCSFYP 926
++ TYY++DE G L+ + S +P
Sbjct 964 VNLPTYYIYDEEGGNDLSLPVMISEWP 990
>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=rep PE=1 SV=1
Length=6684
Score = 4213 bits (10927), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2240/4896 (46%), Positives = 3057/4896 (62%), Gaps = 197/4896 (4%)
Query 2263 CTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWD----L 2318
C G + Y NS+ + A C SI C CL+ D L + L+ S W+ L
Sbjct 1921 CNGAVQAYKNSSFIKSAV-CGNSILCKACLASYDELADFQHLQVTWDFKSDPLWNRLVQL 1979
Query 2319 TAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPIS 2378
+ F +A + Y+ R F + ++ + L+ SYF ++ SW + ++V IS
Sbjct 1980 SYFAFLAVFGNNYV---RCFLMYFVSQYLNLWLSYFG--YVEYSWFL----HVVNFESIS 2030
Query 2379 AMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYA 2438
A + + K H+V C++ +C C + R TR+ +VNG ++ YV+A
Sbjct 2031 AEFVIVVIVVKAVLALK---HIVFACSNPSCKTCSRTARQTRIPIQVVVNGSMKTVYVHA 2087
Query 2439 NGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKN 2498
NG FCK HN+ C NCD++ +TFI DE+ RDLS K+ + TD+S V V +
Sbjct 2088 NGTGKFCKKHNFYCKNCDSYGFENTFICDEIVRDLSNSVKQTVYATDRSHQEVTKVECSD 2147
Query 2499 GSIHLY---------FDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKC 2549
G Y +D +K + L + LD+ + GS NV
Sbjct 2148 GFYRFYVGDEFTSYDYDVKHKKYSSQEVLKSMLLLDDFIVYSPSGSALANV--------- 2198
Query 2550 EESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKL 2609
++A VY+SQL+ +PI +++ L+ D+ S + +F+A N ++FNV + +
Sbjct 2199 -----RNACVYFSQLIGKPIKIVNSDLLEDL--SVDFKGALFNAKKNVIKNSFNVDVSEC 2251
Query 2610 KTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDS 2669
K L E + +L+ STF A +H+ I +T S
Sbjct 2252 KNL-----DECYRACNLNVSFSTFEMAVNN------------------AHRFGILITDRS 2288
Query 2670 CNNYMLTYNK--VENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRK 2727
NN+ + K ++ D+G C+ A+ +NA+V +++W +DF +LS +K
Sbjct 2289 FNNFWPSKVKPGSSGVSAMDIGKCMTSDAKIVNAKVLTQRGKSVVWLSQDFAALSSTAQK 2348
Query 2728 QIRSAAKKNNLPFKLTCATTRQVVNV----VTTKIALKGGK---IVNNWLKQLIKVTLVF 2780
+ + + F LT ++ T ++ K G V LKQ++ + VF
Sbjct 2349 VLVKTFVEEGVNFSLTFNAVGSDDDLPYERFTESVSPKSGSGFFDVITQLKQIVILVFVF 2408
Query 2781 LFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQ 2840
+F+ L + V ++ S+E Y I G+ + T +C N + F WF
Sbjct 2409 IFICG---LCSVYSVATQSYIESAEGYDYMVIKNGIVQPFDDTISCVHNTYKGFGDWFKA 2465
Query 2841 RGGSY-TNDKACPLIAA-VITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYT 2898
+ G T K+CP++ V E +P +P + + G L F V N+CY
Sbjct 2466 KYGFIPTFGKSCPIVVGTVFDLENMRPIPDVPAYV--SIVGRSLVFAINAAFGVTNMCYD 2523
Query 2899 PSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMD 2958
+ D CV CT G V YC ++EG+ Y L PD Y
Sbjct 2524 HTGNAVSKDSYFDTCVFNTACTTLTGLGGTIV-YCAKQGLVEGAKLYSDLMPDYYYEHAS 2582
Query 2959 GSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVF 3018
G++++ P +R V T + YCR G C S+AG C +V +N++ G
Sbjct 2583 GNMVKLPAIIRGLGLRFVKTQATTYCRVGECIDSKAGFCFGGDNWFVYDNEFGN---GYI 2639
Query 3019 CGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVV 3078
CG + N+F + + S +++ I+A + + Y ++F++ FG+
Sbjct 2640 CGNSVLGFFKNVFKLFNSNMSVVATSGAMLVNIIIACLAIAMCYGVLKFKKIFGDC---- 2695
Query 3079 AFNTLLFLMSFTVLCLTPVYSFLPG--VYSVIYLYLTFYLTNDVSF--LAHIQWMVMFTP 3134
T L +M L + V F+ + +IY + +++T +++ + +++ +
Sbjct 2696 ---TFLIVMIIVTLVVNNVSYFVTQNTFFMIIYAIVYYFITRKLAYPGILDAGFIIAYIN 2752
Query 3135 LVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFNGVSF-STFEEAALCTFLLNKEMY 3190
+ P+++ AYI+ Y + K +V +F G F FE AA+ TF+++ Y
Sbjct 2753 MAPWYVITAYILVF----LYDSLPSLFKLKVSTNLFEGDKFVGNFESAAMGTFVIDMRSY 2808
Query 3191 LKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLY 3250
+ + + + Y +NKYKY++G+M YR A HL KAL D+S + +D+LY
Sbjct 2809 ETIVNST--SIARIKSYANSFNKYKYYTGSMGEADYRMACYAHLGKALMDYSVNRTDMLY 2866
Query 3251 QPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSE 3310
PP S+ S LQSG RKMA PSG VE C+V+V+ G LNGLWL D V CPRHVI S+
Sbjct 2867 TPPTVSVNST-LQSGLRKMAQPSGLVEPCIVRVSYGNNVLNGLWLGDEVICPRHVI-ASD 2924
Query 3311 DMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQ 3370
NYE+ + HNF V NV L V+ + L LKV+ NP TP++KF I+
Sbjct 2925 TTRVINYENEMSSVRLHNFSVSKNNVFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIK 2984
Query 3371 PGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMEL 3430
G++F++LACY G P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL
Sbjct 2985 AGESFNILACYEGCPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLEL 3044
Query 3431 PTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTL 3490
G H G++ EG YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + +L
Sbjct 3045 GNGSHVGSNFEGEMYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSL 3104
Query 3491 NDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALL 3550
+N A ++ L+ D L+A+TG +V + S+ L G GRTIL L
Sbjct 3105 ESYNTWAKTNSFTELSS--TDAFSMLAAKTGQSVEKLLDSIVRL-NKGFGGRTILSYGSL 3161
Query 3551 EDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLY--- 3607
DEFTP +V+RQ GV Q+ ++ I+T++ +L + L FF+Y
Sbjct 3162 CDEFTPTEVIRQMYGVNLQAGKVKS-------FFYPIMTAMTILFA---FWLEFFMYTPF 3211
Query 3608 ---ENAFLPFAMGIIAM-SAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRI 3663
F+ + + + S + +KHK F F+LPS+ V N+ + S+ +
Sbjct 3212 TWINPTFVSIVLAVTTLISTVFVSGIKHKMLFFMSFVLPSVILVTAHNL-FWDFSYYESL 3270
Query 3664 MTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYY 3723
+ ++ +T ++ ++ ++ + + R + + +L + V
Sbjct 3271 QSIVENTNTMFLPVDMQGVMLTVFCFIVFVTYSVRFFTCKQSWFSLAVTTILVIFNMVKI 3330
Query 3724 GNALDQA----------ISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
D+ ++M +I+S+T+ VV +A IV +CV P F++
Sbjct 3331 FGTSDEPWTENQIAFCFVNMLTMIVSLTTKDWMVVIASYRIAYYIV-VCV--MPSAFVSD 3387
Query 3774 -NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK 3832
++CI +VY GY CY+G+ +NR+ +T GVY + VS E +YM + L PK
Sbjct 3388 FGFMKCISIVYMACGYLFCCYYGILYWVNRFTCMTCGVYQFTVSAAELKYMTANNLSAPK 3447
Query 3833 NSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV 3892
N+ DA L+ KL+GVGGK IK++TVQSK++++KCT+VVLL +L ++ VES+SK W CV
Sbjct 3448 NAYDAMILSAKLIGVGGKRNIKISTVQSKLTEMKCTNVVLLGLLSKMHVESNSKEWNYCV 3507
Query 3893 QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP 3952
LHN+I L D EK+++L++ LS D+++L E +N LQ++AS +++LP
Sbjct 3508 GLHNEINLCDDPEIVLEKLLALIAFFLSKHNTCDLSELIESYFENTTILQSVASAYAALP 3567
Query 3953 SYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQM 4012
S+ A A+ E+A N S +LK+L K+ N+AKS+F+R+A++Q+KL+KMA+QA M
Sbjct 3568 SWIALEKARADLEEAKKNDVSPQILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAAASM 3627
Query 4013 YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV 4072
YK+AR+ D+++K+ SAM ++LF ML+KLD ++N II+ AR+G +PL+IIP +A +L+V
Sbjct 3628 YKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATRLVV 3687
Query 4073 VIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALR 4132
+ P + YA A+W I +V DA+ V L E++ N NL WPL +T R
Sbjct 3688 ITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAANELNLTWPLSITCER 3747
Query 4133 ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLK 4192
KLQNNE+ P L++ + A T + A + G F+ A ++ +LK
Sbjct 3748 T---TKLQNNEIMPGKLKERAVRASATLDGEAFGSGKALMASESGKSFMYAFIASDNNLK 3804
Query 4193 WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRL 4252
+ ++ ++ I ELE P RF D GP+VKYLYF+K LN L RG VLG + ATVRL
Sbjct 3805 YVKWESNNDI--IPIELEAPLRFYVDGANGPEVKYLYFVKNLNTLRRGAVLGYIGATVRL 3862
Query 4253 QAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP 4312
QAG TE P+NS++L+ CAF+ D AKAY D + G QP+ NCVKML G G A+T
Sbjct 3863 QAGKPTEHPSNSSLLTLCAFSPDPAKAYVDAVKRGMQPVNNCVKMLSNGAGNGMAVTNGV 3922
Query 4313 EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTV 4372
EAN Q+S+GGAS C+YCRCH++HP G C KGK+VQIPT DP+ F ++N VC V
Sbjct 3923 EANTQQDSYGGASVCIYCRCHVEHPAIDGLCRYKGKFVQIPTG-TQDPIRFCIENEVCVV 3981
Query 4373 CGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYND 4432
CG W GC CD R M QS+LNRV G SAARL PC GT D V RAFDIYN
Sbjct 3982 CGCWLNNGCMCD--RTSMQSFTVDQSYLNRVRGSSAARLEPC-NGTDPDHVSRAFDIYNK 4038
Query 4433 KVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHD 4492
VA KFLKTNC RF+ D+ D +Y++VKR T + HE+ YN LKD AVA+HD
Sbjct 4039 DVACIGKFLKTNCSRFRNLDKHD----AYYIVKRCTKTVMDHEQVCYNDLKDSGAVAEHD 4094
Query 4493 FFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKK 4552
FF ++ +++R+ LTKYTM DL YA+R+FDE NC+ LKEILVT C +++F K
Sbjct 4095 FFTYKEGRCEFGNVARRNLTKYTMMDLCYAIRNFDEKNCEVLKEILVTVGACTEEFFENK 4154
Query 4553 DWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFG 4612
DW+D VEN I VYA LG V A+LK V FCDA+ G +GV+TLDNQDLNGN+YDFG
Sbjct 4155 DWFDPVENEAIHEVYAKLGPIVANAMLKCVAFCDAIVEKGYIGVITLDNQDLNGNFYDFG 4214
Query 4613 DFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDL-TKPYIKWDLLKYDFTEER 4671
DF++T PG G V SYYS +MP++ +T L +E+ V +D+ Y ++DLL YDFTE +
Sbjct 4215 DFVKTAPGFGCACVTSYYSYMMPLMGMTSCLESENFVKSDIYGSDYKQYDLLAYDFTEHK 4274
Query 4672 LKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVP 4731
LF +YFKYWD+TYHPNC +C D CI+HCANFN LFS P T+FGPLVRK+ +DGVP
Sbjct 4275 EYLFQKYFKYWDRTYHPNCSDCTSDECIIHCANFNTLFSMTIPMTAFGPLVRKVHIDGVP 4334
Query 4732 FVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVA 4791
VV+ GYHF++LG+V N DV L + +LS +LL + DP + AS LLD+RT CFS+A
Sbjct 4335 VVVTAGYHFKQLGIVWNLDVKLDTMKLSMTDLLRFVTDPTLLVASSPALLDQRTVCFSIA 4394
Query 4792 ALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYN 4851
AL+ + +QTVKPG+FNKDFYDF +GFF+EGS + LKHFFFAQ G AA++D++YYRYN
Sbjct 4395 ALSTGITYQTVKPGHFNKDFYDFITERGFFEEGSELTLKHFFFAQGGEAAMTDFNYYRYN 4454
Query 4852 LPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSM 4911
T+ DI Q FV ++V KYF+CYDGGCINA +V+V N DKSAG+P NK+GKARLYY+++
Sbjct 4455 RVTVLDICQAQFVYKIVGKYFECYDGGCINAREVVVTNYDKSAGYPLNKFGKARLYYETL 4514
Query 4912 SYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSI 4971
SYE+QDALFA TKRNV+PT+TQMNLKYAIS K RARTV GVS+ STMT RQ+HQK LKSI
Sbjct 4515 SYEEQDALFALTKRNVLPTMTQMNLKYAISGKARARTVGGVSLLSTMTTRQYHQKHLKSI 4574
Query 4972 AATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLA 5031
AATR ATVVIG++KFYGGW NMLK + DV+N LMGWDYPKCDRA+PNM+R+ ++++L
Sbjct 4575 AATRNATVVIGSTKFYGGWDNMLKNLMRDVDNGCLMGWDYPKCDRALPNMIRMASAMILG 4634
Query 5032 RKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQA 5091
KH CC+ + RFYRL+NE AQVL+E+V C G Y KPGGT+SGD TTAYANS FNI QA
Sbjct 4635 SKHVGCCTHNDRFYRLSNELAQVLTEVVHCTGGFYFKPGGTTSGDGTTAYANSAFNIFQA 4694
Query 5092 VTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILS 5151
V+ANVN LL D N + V+++Q ++Y+ YR+ +D +FV E+++YLRKHFSMMILS
Sbjct 4695 VSANVNKLLGVDSNACNNVTVKSIQRKIYDNCYRSSSIDEEFVVEYFSYLRKHFSMMILS 4754
Query 5152 DDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTML 5211
DD VVC+N YA G VA I FK+ LYYQNNVFMS +KCW E DL+ GPHEFCSQHT+
Sbjct 4755 DDGVVCYNKDYADLGYVADINAFKATLYYQNNVFMSTSKCWVEPDLSVGPHEFCSQHTLQ 4814
Query 5212 VKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYAD 5271
+ D YLPYPDPSRIL AG FVDDIVKTD +M+ER+VSLAIDAYPLTKHP Y
Sbjct 4815 IVGPDGDYYLPYPDPSRILSAGVFVDDIVKTDNVIMLERYVSLAIDAYPLTKHPKPAYQK 4874
Query 5272 VFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVL 5331
VF+ L +++ L L +LD +SV + + ++W EFY ++Y TVLQA G CV+
Sbjct 4875 VFYTLLDWVKHLQKNLNAGVLDSFSVTMLEEGQDKFWSEEFYASLYEKSTVLQAAGMCVV 4934
Query 5332 CNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGG 5391
C SQT LRCG C+RRP LC KC YDHV+ T HK ++S+ PYVC+ GC+V DVT+L+LGG
Sbjct 4935 CGSQTVLRCGDCLRRPLLCTKCAYDHVMGTKHKFIMSITPYVCSFNGCNVNDVTKLFLGG 4994
Query 5392 MSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCT 5451
+SYYC +HKP +SFPLCANG VFGLYK++ VGS+ V DFN +A DWTN DY LAN
Sbjct 4995 LSYYCMNHKPQLSFPLCANGNVFGLYKSSAVGSEAVEDFNKLAVSDWTNVEDYKLANNVK 5054
Query 5452 ERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRV 5511
E LK+FAAET+KA EE+ K Y A ++EV+ +E+ L WE K +PPLNRN VFT +++
Sbjct 5055 ESLKIFAAETVKAKEESVKSEYAYAVLKEVIGPKEIVLQWEASKTKPPLNRNSVFTCFQI 5114
Query 5512 TKNSKVQIGEYTFEKGDYG-DAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY 5570
+K++K+Q+GE+ FE+ +YG D+V Y+ T+TYKL G FVLTSH V PL AP LV QE Y
Sbjct 5115 SKDTKIQLGEFVFEQSEYGSDSVYYKSTSTYKLTPGMIFVLTSHNVSPLKAPILVNQEKY 5174
Query 5571 VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVY 5630
I+ LYP NI++ +++ V YQ +G QK++T+QGPPG+GKSH IGL LYYP ARIVY
Sbjct 5175 NTISKLYPVFNIAEAYNTLVPYYQMIGKQKFTTIQGPPGSGKSHCVIGLGLYYPQARIVY 5234
Query 5631 TACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPET 5690
TACSHAAVDALCEKA K +D+CSRIIP R RV+C+ FK N+T QY+FCTVNALPE
Sbjct 5235 TACSHAAVDALCEKAAKNFNVDRCSRIIPQRIRVDCYTGFKPNNTNAQYLFCTVNALPEA 5294
Query 5691 TADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC 5750
+ DIVV DE+SM TNYDLSV+N+RL KH VY+GDP QLPAPRTL+ KG L+P+ +N V
Sbjct 5295 SCDIVVVDEVSMCTNYDLSVINSRLSYKHIVYVGDPQQLPAPRTLINKGVLQPQDYNVVT 5354
Query 5751 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSS 5810
+ M T+GPD+FL C RCPAEIV TVSALVY+NK +S QCFKMF KG + + +S
Sbjct 5355 KRMCTLGPDVFLHKCYRCPAEIVKTVSALVYENKFVPVNPESKQCFKMFVKGQVQIESNS 5414
Query 5811 AINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIF 5870
+IN Q+ VV+ FL NP WRKAVFISPYNSQN VA ++LGL TQTVDS+QGSEYDYVI+
Sbjct 5415 SINNKQLEVVKAFLAHNPKWRKAVFISPYNSQNYVARRLLGLQTQTVDSAQGSEYDYVIY 5474
Query 5871 TQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVT 5930
TQT++T H+ NVNRFNVAITRAKVGILCIM DR +Y+ L F L+ + LQA+ T
Sbjct 5475 TQTSDTQHATNVNRFNVAITRAKVGILCIMCDRTMYENLDFYELKDSK---IGLQAKPET 5531
Query 5931 -GLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMN 5988
GLFKDCSK + P A T++S+ FKT +GL V+I KD+ Y +IS MGF+
Sbjct 5532 CGLFKDCSKSEQYIPPAYATTYMSLSDNFKTSDGLAVNIG--TKDVKYANVISYMGFRFE 5589
Query 5989 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 6048
+ GY +F TR+ A+R+VRAW+GFDVEG H + VGTN+PLQLGFS GV+ V G
Sbjct 5590 ANIPGYHTLFCTRDFAMRNVRAWLGFDVEGAHVCGDNVGTNVPLQLGFSNGVDFVVQTEG 5649
Query 6049 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 6108
V T V A+ PPG+QF HLIPLM KG PW++VR +IVQM+ D LSD ++F
Sbjct 5650 CVITEKGNSIEVVKARAPPGEQFAHLIPLMRKGQPWHIVRRRIVQMVCDYFDGLSDILIF 5709
Query 6109 VLWAHGFELTSMKYFVKIG-PERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMI 6167
VLWA G ELT+M+YFVKIG P++ C C + ATC+S++ YAC+ H++G DY+YNP+ I
Sbjct 5710 VLWAGGLELTTMRYFVKIGRPQK--CECGKSATCYSSSQSVYACFKHALGCDYLYNPYCI 5767
Query 6168 DVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDE 6227
D+QQWG+TG+L NH C +H N HVAS DAIMTRCLA+H+CFVKRVDW+I YP I +E
Sbjct 5768 DIQQWGYTGSLSMNHHEVCNIHRNEHVASGDAIMTRCLAIHDCFVKRVDWSIVYPFIDNE 5827
Query 6228 LKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYK 6287
KIN A R VQ V+KAAL +HD+GNPK I+C + W YD P ++
Sbjct 5828 EKINKAGRIVQSHVMKAALKIFNPAAIHDVGNPKGIRCA-TTPIPWFCYDRDPINN---N 5883
Query 6288 IEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVN 6347
+ L Y Y H +G+ LFWNCNVD YP SIVCRFDTR S L+L GC+GG+LYVN
Sbjct 5884 VRCLDYDYMVHGQ--MNGLMLFWNCNVDMYPEFSIVCRFDTRTRSKLSLEGCNGGALYVN 5941
Query 6348 KHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 6407
HAFHTPA+D+ AF LK +PFFYY DS CE V +YVPLKS CIT+CN+GGA
Sbjct 5942 NHAFHTPAYDRRAFAKLKPMPFFYYDDSNCE----LVDGQPNYVPLKSNVCITKCNIGGA 5997
Query 6408 VCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTR---LQSLENVAFNVVNK 6464
VC+ HA YR Y++ YN+ + AGF++W + FDTY LW+ F LQSLENVAFNVV K
Sbjct 5998 VCKKHAALYRAYVEDYNIFMQAGFTIWCPQNFDTYMLWHGFVNSKALQSLENVAFNVVKK 6057
Query 6465 GHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKIL 6524
G F G +G++P ++I + + + D +F NKT+LP NVAFEL+AKR + P + IL
Sbjct 6058 GAFTGLKGDLPTAVIADKIMVRDGPTDKCIFTNKTSLPTNVAFELYAKRKLGLTPPLTIL 6117
Query 6525 NNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVD 6584
NLGV V+WDY+ + P T VCS TD+ + + FD + G +
Sbjct 6118 RNLGVVATYKFVLWDYEAERPFSNFTKQVCSYTDLDSE--------VVTCFDNSIAGSFE 6169
Query 6585 LFRNARNGVLITEGSVKGLQPSVGPKQASLNG--VTLIGEAVKTQFNYYKKVDGVVQQLP 6642
F R+ VLI+ +VKGL ++ + LN V+ +G T + Y +K V+Q+
Sbjct 6170 RFTTTRDAVLISNNAVKGLS-AIKLQYGLLNDLPVSTVGNKPVTWYIYVRKNGEYVEQI- 6227
Query 6643 ETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHL 6702
++Y+TQ R + FKPRS ME DFL + FI++Y LE Y FEH+V+GD S + +GG+HL
Sbjct 6228 DSYYTQGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEHVVFGDVSKTTIGGMHL 6287
Query 6703 LIGLAKRFKESPFELEDFI-PMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQ 6761
LI + K F +++F+ DST+K+ IT A SSK VC+ +D+LLDDFV IIKS
Sbjct 6288 LISQVRLAKMGLFSVQEFMNNSDSTLKSCCITYADDPSSKNVCTYMDILLDDFVTIIKSL 6347
Query 6762 DLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLE 6821
DL+VVSKVV V +D +MLWC++ H++TFYP+LQS++ W PG +MP LYK+QRM LE
Sbjct 6348 DLNVVSKVVDVIVDCKAWRWMLWCENSHIKTFYPQLQSAE-WNPGYSMPTLYKIQRMCLE 6406
Query 6822 KCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTA 6881
+C+L NYG LP GI NV KYTQLCQYLNT TL VP+ MRV+H GA GVAPG+
Sbjct 6407 RCNLYNYGAQVKLPDGITTNVVKYTQLCQYLNTTTLCVPHKMRVLHLGAAGASGVAPGST 6466
Query 6882 VLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKEN 6941
VLR+WLP +LVD+DL D+VSDAD ++ GDC +++ +K+DL++SD+YD TK++ EN
Sbjct 6467 VLRRWLPDDAILVDNDLRDYVSDADFSVTGDCTSLYIEDKFDLLVSDLYDGSTKSIDGEN 6526
Query 6942 DSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSE 7001
SK+GFFTYI GFI++KL+LGGSVAIKITE SWN DLY+L+ F +WT F T+VN SSSE
Sbjct 6527 TSKDGFFTYINGFIKEKLSLGGSVAIKITEFSWNKDLYELIQRFEYWTVFCTSVNTSSSE 6586
Query 7002 AFLIGCNYLGK--PREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMS 7059
FLIG NYLG + +DG +MHANYIFWRN+ + LS S+ D KF + +++
Sbjct 6587 GFLIGINYLGPYCDKAIVDGNIMHANYIFWRNSTIMALSHNSVLDTPKFKCRCNNALIVN 6646
Query 7060 LKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
LKE ++N+M++ LL KG+L+IR N +++ + VN
Sbjct 6647 LKEKELNEMVIGLLRKGKLLIRNNGKLLNFGNHFVN 6682
Score = 62.8 bits (151), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 69/288 (24%), Positives = 123/288 (43%), Gaps = 38/288 (13%)
Query 986 QTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADI 1045
+ V QQ E+N+++ + ++ P+ + + P + +++ + G L + N
Sbjct 1293 EKVEQQPIVEENKSSIEKEEIQ-SPKNDDLILPFYKAGKLSFYQGALDVLINF------- 1344
Query 1046 VEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVL 1105
++P V+VNAAN LKH GGVA A++ T + S DY+ N + G +
Sbjct 1345 ------LEPDVIVNAANGDLKHMGGVARAIDVFTGGKLTERSKDYLKKNKSIAPGNAVFF 1398
Query 1106 SGHNLAKH--CLHVVGPNVNKGEDIQLLKSAYENFNQHE-VLLAPLLSAGIFGADPIHSL 1162
N+ +H L+ VGP L + Y+ + E +L PL+S GIF
Sbjct 1399 --ENVIEHLSVLNAVGPRNGDSRVEAKLCNVYKAIAKCEGKILTPLISVGIF-------- 1448
Query 1163 RVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKI--AEIPKEEVKPFITESKP 1220
VR L K + D+ ++ F+ E+Q + IP + + +
Sbjct 1449 -----NVRLETSLQCLLKTVNDRGLNVFVYTDQERQTIENFFSCSIPVNVTEDNVNHERV 1503
Query 1221 SVEQRKQDDKKIKACV----EEVTTTLEETKFLTENLLLYIDINGNLH 1264
SV K +++K V ++VT L + + ++ IDI+ H
Sbjct 1504 SVSFDKTYGEQLKGTVVIKDKDVTNQLPSAFDVGQKVIKAIDIDWQAH 1551
Score = 49.7 bits (117), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 57/235 (24%), Positives = 94/235 (40%), Gaps = 34/235 (14%)
Query 1656 WKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALIL 1715
+K +NG +K DNNC++ LQ + FN +A+ + + G+ +F L
Sbjct 1075 FKTTNLNGKIILKQGDNNCWINACCYQLQAFDF-FN----NEAWEKFKKGDVMDFVNLCY 1129
Query 1716 AYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
A G GD + + + + K VL C CG+++ L E ++ T
Sbjct 1130 AATTLARGHSGDAEYLLELMLN--DYSTAKIVLAAKCG-CGEKEIVL---ERAVFKLTPL 1183
Query 1776 YEQFKKGVQIPC----TCGKQATKY-------LVQQESPFVMMSAPPAQYELKHGTFTCA 1824
E F GV C TC + + ++ +++P M P + +
Sbjct 1184 KESFNYGVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHAV-------- 1235
Query 1825 SEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKP 1879
YTG Q GHY + E YC+DG + K + + + +F N T KP
Sbjct 1236 --YTGTTQNGHY-MVDDIEHGYCVDG-MGIKPLKKRCYTSTLFINANVMTRAEKP 1286
Score = 41.6 bits (96), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 103/455 (23%), Positives = 149/455 (33%), Gaps = 96/455 (21%)
Query 144 DLGDELGTDPYEDFQENWNTKHSSGVTREL-MRELNGGAYTRYVDNNFCGPDGYPL--EC 200
DL L T+P Q + +GV + ++ G YVD CG DG P+
Sbjct 71 DLKPVLLTEPSVMLQGFIVRANCNGVLEDFDLKIARTGRGAIYVDQYMCGADGKPVIEGD 130
Query 201 IKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLA 260
KD D I+ + Y C AW T R EK QT F I+
Sbjct 131 FKDYFGDE-----------DIIEFEGEEYHC-------AWTTVRDEKPLNQQTLFTIQEI 172
Query 261 KKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVY-----PVASPNECNQM 315
+ +N + P+ P N + + P V+K + +Y P +C
Sbjct 173 Q----YNLDIPH-KLP-NCATRHVAPPVKKNSKIVLSEDYKKLYDIFGSPFMGNGDCLSK 226
Query 316 CLSTL------MKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIY 369
C TL ++C CG S GD+ CG K G T P +AVV
Sbjct 227 CFDTLHFIAATLRCP-CGSESSGVGDWTGFKTACCGLSGKVK-GVTLGDIKPGDAVV--- 281
Query 370 CPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASA 429
T + G F CV Y G + W +
Sbjct 282 -------------------------TSMSAGKGVKFFANCVLQYAGDVEGVSIW--KVIK 314
Query 430 NIGCNHTGVVGEGSEGLNDNLLEILQKEKVNIN-----IVGDFKLNEEIAIILASFSAST 484
+ T V G EG ++ ++ K V + I GD II ST
Sbjct 315 TFTVDET-VCTPGFEGELNDFIKPESKSLVACSVKRAFITGDIDDAVHDCIITGKLDLST 373
Query 485 SAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQ---------KSILSPLYA 535
+ F GL +K V+ CG V AW + E+ K I + +
Sbjct 374 NLFGNV--GLLFKKTPWFVQKCGALFVD-------AWKVVEELCGSLTLTYKQIYEVVAS 424
Query 536 FASEAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
+ A +V + T N V+ L + +L
Sbjct 425 LCTSAFTIVN--YKPTFVVPDNRVKDLVDKCVKVL 457
Score = 37.4 bits (85), Expect = 8.8, Method: Compositional matrix adjust.
Identities = 61/286 (21%), Positives = 107/286 (37%), Gaps = 29/286 (10%)
Query 1567 TIKVFTTVDNINLHTQVVDMSMTYGQQF-GPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+I V T DN+N V TYG+Q G + DVT P G+
Sbjct 1488 SIPVNVTEDNVNHERVSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAFDVGQKVI-----K 1542
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSI--KWADNNCYLATALLTL 1683
+ ++ +Y D + SA +H +K+ V I K DNNC++ L L
Sbjct 1543 AIDIDWQAHYGFRDAAAF----SASSH-DAYKFEVVTHSNFIVHKQTDNNCWINAICLAL 1597
Query 1684 QQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDS 1743
Q+++ ++ P ++ + + F ++ GE GD E M + +
Sbjct 1598 QRLKPQWKFPGVRGLWNEFLERKTQGFVHMLYHISGVKKGEPGDA-ELMLHKLGDLMDND 1656
Query 1744 CKRVL--NVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQE 1801
C+ ++ C C + + + V A L+ G C G + Q +
Sbjct 1657 CEIIVTHTTACDKCAKVEKFVGPVVA----APLAIH----GTDETCVHGVSVNVKVTQIK 1708
Query 1802 SPFVMMS--APPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETL 1845
+ S P L+ + C Y+G+ + GHY + ++ L
Sbjct 1709 GTVAITSLIGPIIGEVLEATGYIC---YSGSNRNGHYTYYDNRNGL 1751
>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709
Score = 4188 bits (10862), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2238/4943 (45%), Positives = 3067/4943 (62%), Gaps = 199/4943 (4%)
Query 2214 SFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNS 2273
+ NY++ N L I LLL + L Y ++ V+ C+G + Y NS
Sbjct 1903 TLNYVRQLNKPALWRYIKLVLLL-IALYHFFYLFVSIPVVHK-----LACSGSVQAYSNS 1956
Query 2274 TNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWD----LTAFGLVAEWFL 2329
+ V + C SI C CL+ D L + L+ S W+ L+ F +A +
Sbjct 1957 SFVK-SEVCGNSILCKACLASYDELADFDHLQVSWDYKSDPLWNRVIQLSYFIFLAVFGN 2015
Query 2330 AYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFAS 2389
Y+ ++V + + L+ SYF ++ SW + ++V IS + +
Sbjct 2016 NYVRCLLMYFV---SQYLNLWLSYFG--YVKYSWFL----HVVNFESISVEFVIIVVVFK 2066
Query 2390 FYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHN 2449
K H+ CN+ +C C K R TR+ +VNG ++ YV+ANG CK HN
Sbjct 2067 AVLALK---HIFLPCNNPSCKTCSKIARQTRIPIQVVVNGSMKTVYVHANGTGKLCKKHN 2123
Query 2450 WNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLY----- 2504
+ C NCD++ TFI DE+ RDLS K+ + TD+S V V +G Y
Sbjct 2124 FYCKNCDSYGFDHTFICDEIVRDLSNSIKQTVYATDRSYQEVTKVECTDGFYRFYVGEEF 2183
Query 2505 ----FDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVY 2560
+D +K + L LD+ N GS +S ++ VY
Sbjct 2184 TAYDYDVKHKKYSSQEVLKTMFLLDDFIVYNPSGS--------------SLASVRNVCVY 2229
Query 2561 YSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAEL 2620
+SQL+ +PI +++ L+ D+ S + +F+A N ++FNV + + K L E
Sbjct 2230 FSQLIGRPIKIVNSELLEDL--SVDFKGALFNAKKNVIKNSFNVDVSECKNL-----EEC 2282
Query 2621 AKNVSLDNVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNK- 2679
K +LD STF A +H+ I +T S NN+ + K
Sbjct 2283 YKLCNLDVTFSTFEMAINN------------------AHRFGILITDRSFNNFWPSKIKP 2324
Query 2680 -VENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNL 2738
++ D+G C+ A+ +NA+V +++W +DF +LS +K + + +
Sbjct 2325 GSSGVSAMDIGKCMTFDAKIVNAKVLTQRGKSVVWLSQDFSTLSSTAQKVLVKTFVEEGV 2384
Query 2739 PFKLTCATTRQVVNV----VTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVH 2794
F LT ++ T ++ K G + LKQL ++ + ++ L +
Sbjct 2385 NFSLTFNAVGSDEDLPYERFTESVSAKSGSGFFDVLKQLKQLFWCLVLFITLYGLCSVYS 2444
Query 2795 VMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSY-TNDKACPL 2853
V ++ S+E Y I GV + + C N + F WF + G T DK+CP+
Sbjct 2445 VATQSYIDSAEGYDYMVIKNGVVQSFDDSINCVHNTYKGFAVWFKAKHGFVPTFDKSCPI 2504
Query 2854 IAAVITREVGFV--VPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
+ + ++G + +P +P + G L F V N+CY + +
Sbjct 2505 VLGTVF-DLGNMRPIPDVPAYVALV--GRSLVFAINAAFGVTNVCYDHTGAAVSKNSYFD 2561
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEG 2971
CV + CT G V YC ++EG+ Y L PD Y G++++ P
Sbjct 2562 TCVFNSACTTLTGIGGTVV-YCAKQGLVEGAKLYSELLPDYYYEHASGNMVKIPAIIRSF 2620
Query 2972 SVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMF 3031
+R V T + YCR G C S+AG C +V + ++ G CG + N+F
Sbjct 2621 GLRFVKTQATTYCRVGECTESQAGFCFGGDNWFVYDKEFG---DGYICGSSTLGFFKNVF 2677
Query 3032 TPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTV 3091
+ + S +++A ++A + + Y ++F++ FG+ TLL +M
Sbjct 2678 ALFNSNMSVVATSGAMLANIVIACLAIAVCYGVLKFKKIFGDC-------TLLVVMIIVT 2730
Query 3092 LCLTPVYSFLPG--VYSVIYLYLTFYLTNDVSFLAHIQ--WMVMFTPLVPFWITIAYIIC 3147
L + V F+ + ++Y + ++ T +++ + +++ + + P+++ + YI+
Sbjct 2731 LVVNNVSYFVTQNTFFMIVYAIIYYFTTRKLAYPGVLDAGFIIAYLNMAPWYVLVLYIMV 2790
Query 3148 ISTKHFYWFFSNYLKRRV---VFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQ 3203
Y + K +V +F G F +FE AA+ TF+++ Y L + L +
Sbjct 2791 F----LYDSLPSLFKLKVTTNLFEGDKFVGSFESAAMGTFVIDMRSYETLVNST--SLDR 2844
Query 3204 YNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQ 3263
Y +NKYKY++G+M YR A HL KAL D+S S +D+LY PP S+ S LQ
Sbjct 2845 IKSYANSFNKYKYYTGSMGEADYRMACYAHLGKALMDYSVSRNDMLYTPPTVSVNST-LQ 2903
Query 3264 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 3323
SG RKMA PSG VE C+V+V G LNGLWL D V CPRHVI + + NYE+ L
Sbjct 2904 SGLRKMAQPSGVVEPCIVRVAYGNNVLNGLWLGDEVICPRHVIASDTSRV-INYENELSS 2962
Query 3324 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 3383
HNF + N L V+ + L LKV+ NP TP++KF ++PG++F++LACY G
Sbjct 2963 VRLHNFSIAKNNAFLGVVSAKYKGVNLVLKVNQVNPNTPEHKFKSVRPGESFNILACYEG 3022
Query 3384 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 3443
P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++LEG
Sbjct 3023 CPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGTLYFVYMHHLELGNGSHVGSNLEGE 3082
Query 3444 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3503
YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + TL +N A ++
Sbjct 3083 MYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMTLESYNAWAKTNSFT 3142
Query 3504 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 3563
+ D L+A+TG +V + + L G GRTIL L DEFTP +V+RQ
Sbjct 3143 EIVS--TDAFNMLAAKTGYSVEKLLECIVRL-NKGFGGRTILSYGSLCDEFTPTEVIRQM 3199
Query 3564 SGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLY------ENAFLPFAMG 3617
GV QS ++I ++T++ +L + L FF+Y F+ +
Sbjct 3200 YGVNLQSGKVKSI-------FYPMMTAIAILFA---FWLEFFMYTPFTWINPTFVSVVLA 3249
Query 3618 IIAM-SAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSG 3676
I + S + +KHK F F++PS+ N+V+ ++ + ++ V+T+
Sbjct 3250 ITTLVSVLLVAGIKHKMLFFMSFVMPSVILATAHNVVW-DMTYYESLQVLVENVNTTFLP 3308
Query 3677 FKLKDCVMYASAVVLLILMTAR------TVYDDGARRVWTLMNVLTLVYKVYYGNALDQ- 3729
++ ++ VV+ ++ T R + + A ++ + N++ L+ + D
Sbjct 3309 VDMQGVMLALFCVVVFVICTIRFFTCKQSWFSLFATTIFVMFNIVKLLGMIGEPWTDDHF 3368
Query 3730 ---AISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFL 3786
++M ++IS+T+ VV +A IV ++ P F ++C+ ++Y
Sbjct 3369 LLCLVNMLTMLISLTTKDWFVVFASYKVAYYIVVYVMQ--PAFVQDFGFVKCVSIIYMAC 3426
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
GY CY+G+ +NR+ +T GVY + VS E +YM + L PK + DA L+ KL+G
Sbjct 3427 GYLFCCYYGILYWVNRFTCMTCGVYQFTVSPAELKYMTANNLSAPKTAYDAMILSFKLMG 3486
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG IK++TVQSK++++KCT+VVLL +L ++ VES+SK W CV LHN+I L D
Sbjct 3487 IGGGRNIKISTVQSKLTEMKCTNVVLLGLLSKMHVESNSKEWNYCVGLHNEINLCDDPDA 3546
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
EK+++L++ LS D++ L E +N LQ++AS +++LPS+ A+ A+ E+
Sbjct 3547 VLEKLLALIAFFLSKHNTCDLSDLIESYFENTTILQSVASAYAALPSWIAYEKARADLEE 3606
Query 3967 AVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVT 4026
A N S +LK+L K+ N+AKSEF+R+A++Q+KL+KMA+QA MYK+AR+ D+++K+
Sbjct 3607 AKKNDVSPQLLKQLTKACNIAKSEFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIV 3666
Query 4027 SAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDG 4086
SAM ++LF ML+KLD ++N II AR+G +PL+IIP +A +L+VV P+
Sbjct 3667 SAMHSLLFGMLKKLDMSSVNTIIEQARNGVLPLSIIPAASATRLIVVTPNLEVLSKVRQE 3726
Query 4087 TTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSP 4146
YA A+W I +V DA+ V L E++ N N+ WPL +T R KLQNNE+ P
Sbjct 3727 NNVHYAGAIWSIVEVKDANGAQVHLKEVTAANELNITWPLSITCERT---TKLQNNEILP 3783
Query 4147 VALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIY 4206
L++ + A T + A + G F+ A ++ +LK+ ++ ++ I
Sbjct 3784 GKLKEKAVKASATIDGDAYGSGKALMASEGGKSFIYAFIASDSNLKYVKWESNNDV--IP 3841
Query 4207 TELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTV 4266
ELE P RF D GP+VKYLYF+K LN L RG VLG + ATVRLQAG TE P+NS +
Sbjct 3842 IELEAPLRFYVDGVNGPEVKYLYFVKSLNTLRRGAVLGYIGATVRLQAGKPTEHPSNSGL 3901
Query 4267 LSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASC 4326
L+ CAFA D AKAY D + G QP+TNCVKML G G AIT E+N Q+S+GGAS
Sbjct 3902 LTLCAFAPDPAKAYVDAVKRGMQPVTNCVKMLSNGAGNGMAITNGVESNTQQDSYGGASV 3961
Query 4327 CLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQL 4386
C+YCRCH++HP G C KGK+VQ+PT DP+ F ++N VC VCG W GC CD
Sbjct 3962 CIYCRCHVEHPAIDGLCRFKGKFVQVPTG-TQDPIRFCIENEVCVVCGCWLTNGCMCD-- 4018
Query 4387 REPMLQSADAQSFLNRVCGVSAA-RLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNC 4445
R + + QS+LN CGV L PC GT D V RAFDIYN VA KFLKTNC
Sbjct 4019 RTSIQGTTIDQSYLNE-CGVLVQLDLEPC-NGTDPDHVSRAFDIYNKDVACIGKFLKTNC 4076
Query 4446 CRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPH 4505
RF+ D+ D +Y+VVKR T S HE+ YN LKD VA+HDFF ++ +
Sbjct 4077 SRFRNLDKHD----AYYVVKRCTKSVMDHEQVCYNDLKDSGVVAEHDFFLYKEGRCEFGN 4132
Query 4506 ISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILR 4565
++R+ LTKYTM DL YA+R+FDE NC+ LKEILVT C++ +F KDW+D VEN I
Sbjct 4133 VARKDLTKYTMMDLCYAIRNFDEKNCEVLKEILVTLGACNESFFENKDWFDPVENEAIHE 4192
Query 4566 VYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPV 4625
VYA LG V A+LK V FCDA+ G +G++TLDNQDLNGN+YDFGDF++TTPG G
Sbjct 4193 VYARLGPIVANAMLKCVAFCDAIVEKGYIGIITLDNQDLNGNFYDFGDFVKTTPGFGCAC 4252
Query 4626 VDSYYSLLMPILTLTRALTAESHVDTDL-TKPYIKWDLLKYDFTEERLKLFDRYFKYWDQ 4684
V SYYS +MP++ +T L +E+ V +D+ Y ++DLL YDFT+ + KLF +YFK+WD+
Sbjct 4253 VTSYYSYMMPLMGMTSCLESENFVKSDIYGADYKQYDLLAYDFTDHKEKLFHKYFKHWDR 4312
Query 4685 TYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELG 4744
TYHPNC +C D CI+HCANFN LFS P T+FGPLVRK+ +DGVP VV+ GYHF++LG
Sbjct 4313 TYHPNCSDCTSDECIIHCANFNTLFSMTIPSTAFGPLVRKVHIDGVPVVVTAGYHFKQLG 4372
Query 4745 VVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKP 4804
+V N DV L + +LS +LL + DP + AS LLD+RT CFS+AAL+ V +QTVKP
Sbjct 4373 IVWNLDVKLDTMKLSMTDLLRFVTDPTLLVASSPALLDQRTVCFSIAALSTGVTYQTVKP 4432
Query 4805 GNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFV 4864
G+FNKDFYDF +GFF+EGS + LKHFFFAQ G AA++D++YYRYN T+ DI Q FV
Sbjct 4433 GHFNKDFYDFITERGFFEEGSELTLKHFFFAQGGEAAMTDFNYYRYNRVTVLDICQAQFV 4492
Query 4865 VEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTK 4924
++V KYF+CYDGGCINA +V+V N DKSAG+P NK+GKARLYY+++SYE+QDALFA TK
Sbjct 4493 YKIVGKYFECYDGGCINAREVVVTNYDKSAGYPLNKFGKARLYYETLSYEEQDALFALTK 4552
Query 4925 RNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTS 4984
RNV+PT+TQMNLKYAIS K RARTV GVS+ STMT RQ+HQK LKSIAATR ATVVIG++
Sbjct 4553 RNVLPTMTQMNLKYAISGKARARTVGGVSLLSTMTTRQYHQKHLKSIAATRNATVVIGST 4612
Query 4985 KFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRF 5044
KFYGGW NMLK + DV+N LMGWDYPKCDRA+PNM+R+ ++++L KH CC+ S RF
Sbjct 4613 KFYGGWDNMLKNLMRDVDNGCLMGWDYPKCDRALPNMIRMASAMILGSKHVGCCTHSDRF 4672
Query 5045 YRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDG 5104
YRL+NE AQVL+E+V C G Y KPGGT+SGD TTAYANS FNI QAV+ANVN LL D
Sbjct 4673 YRLSNELAQVLTEVVHCTGGFYFKPGGTTSGDGTTAYANSAFNIFQAVSANVNKLLGVDS 4732
Query 5105 NKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYAS 5164
N + V+++Q ++Y+ YR+ +D +FV E+++YLRKHFSMMILSDD VVC+N YA
Sbjct 4733 NACNNVTVKSIQRKIYDNCYRSSSIDEEFVVEYFSYLRKHFSMMILSDDGVVCYNKDYAD 4792
Query 5165 QGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYP 5224
G VA I FK+ LYYQNNVFMS +KCW E DL+ GPHEFCSQHT+ + D YLPYP
Sbjct 4793 LGYVADINAFKATLYYQNNVFMSTSKCWVEPDLSVGPHEFCSQHTLQIVGPDGDYYLPYP 4852
Query 5225 DPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLH 5284
DPSRIL AG FVDDIVKTD +M+ER+VSLAIDAYPLTKHP Y VF+ L +++ L
Sbjct 4853 DPSRILSAGVFVDDIVKTDNVIMLERYVSLAIDAYPLTKHPKPAYQKVFYTLLDWVKHLQ 4912
Query 5285 DELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACI 5344
L +LD +SV + + ++W EFY ++Y TVLQA G CV+C SQT LRCG C+
Sbjct 4913 KNLNAGVLDSFSVTMLEEGQDKFWSEEFYASLYEKSTVLQAAGMCVVCGSQTVLRCGDCL 4972
Query 5345 RRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPIS 5404
RRP LC KC YDHV+ T HK ++S+ PYVC+ GC+V DVT+L+LGG+SYYC HKP +S
Sbjct 4973 RRPLLCTKCAYDHVMGTKHKFIMSITPYVCSFNGCNVNDVTKLFLGGLSYYCMDHKPQLS 5032
Query 5405 FPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKA 5464
FPLCANG VFGLYK++ VGS++V DFN +A DWTN DY LAN E LK+FAAET+KA
Sbjct 5033 FPLCANGNVFGLYKSSAVGSEDVEDFNKLAVSDWTNVEDYKLANNVKESLKIFAAETVKA 5092
Query 5465 TEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTF 5524
EE+ K Y A ++EV+ +E+ L WE K +PPLNRN VFT ++++K++K+Q+GE+ F
Sbjct 5093 KEESVKSEYAYAILKEVIGPKEIVLQWEASKTKPPLNRNSVFTCFQISKDTKIQLGEFVF 5152
Query 5525 EKGDYG-DAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNIS 5583
E+ +YG D+V Y+ T+TYKL G FVLTSH V PL A LV QE Y I+ LYP NI+
Sbjct 5153 EQSEYGSDSVYYKSTSTYKLTPGMIFVLTSHNVSPLKATILVNQEKYNTISKLYPVFNIA 5212
Query 5584 DEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCE 5643
+ +++ V YQ +G QK++T+QGPPG+GKSH IGL LYYP ARIVYTACSHAAVDALCE
Sbjct 5213 EAYNTLVPYYQMIGKQKFTTIQGPPGSGKSHCVIGLGLYYPQARIVYTACSHAAVDALCE 5272
Query 5644 KALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMA 5703
KA K +D+CSRIIP R RV+C+ FK N+T QY+FCTVNALPE + DIVV DE+SM
Sbjct 5273 KAAKNFNVDRCSRIIPQRIRVDCYTGFKPNNTNAQYLFCTVNALPEASCDIVVVDEVSMC 5332
Query 5704 TNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLG 5763
TNYDLSV+N+RL KH VY+GDP QLPAPRTL+ KG L+P+ +N V + + T+GPD+FL
Sbjct 5333 TNYDLSVINSRLSYKHIVYVGDPQQLPAPRTLINKGVLQPQDYNVVTQRVCTLGPDVFLH 5392
Query 5764 TCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREF 5823
C RCPAEIV TVSALVY+NK +S QCFKMF KG + + +S+IN Q+ VV+ F
Sbjct 5393 KCYRCPAEIVKTVSALVYENKFVPVNPESKQCFKMFVKGQVQIESNSSINNKQLEVVKAF 5452
Query 5824 LTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVN 5883
L NP WRKAVFISPYNSQN VA ++LGL TQTVDS+QGSEYDYVI+TQT++T H+ NVN
Sbjct 5453 LAHNPKWRKAVFISPYNSQNYVARRLLGLQTQTVDSAQGSEYDYVIYTQTSDTQHATNVN 5512
Query 5884 RFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVT-GLFKDCSKVITG 5942
RFNVAITRAKVGILCIM DR +Y+ L F L+ + LQA+ T GLFKDCSK
Sbjct 5513 RFNVAITRAKVGILCIMCDRTMYENLDFYELKDSK---IGLQAKPETCGLFKDCSKSEQY 5569
Query 5943 LHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITR 6001
+ P A T++S+ FKT +GL V+I KD+ Y +IS MGF+ + GY +F TR
Sbjct 5570 IPPAYATTYMSLSDNFKTSDGLAVNIG--TKDVKYANVISYMGFRFEANIPGYHTLFCTR 5627
Query 6002 EEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRV 6061
+ A+R+VRAW+GFDVEG H + VGTN+PLQLGFS GV+ V G V T V
Sbjct 5628 DFAMRNVRAWLGFDVEGAHVCGDNVGTNVPLQLGFSNGVDFVVQTEGCVVTEKGNSIEVV 5687
Query 6062 SAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMK 6121
A+ PPG+QF HLIPLM KG PW++VR +IVQM+ D LSD ++FVLWA G ELT+M+
Sbjct 5688 KARAPPGEQFAHLIPLMRKGQPWHIVRRRIVQMVCDYFDGLSDILIFVLWAGGLELTTMR 5747
Query 6122 YFVKIG-PERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQS 6180
YFVKIG P++ C C + ATC+S++ YAC+ H++G DY+YNP+ ID+QQWG+TG+L
Sbjct 5748 YFVKIGRPQK--CECGKSATCYSSSQCVYACFKHALGCDYLYNPYCIDIQQWGYTGSLSM 5805
Query 6181 NHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHM 6240
NH C +H N HVAS DAIMTRCLA+H+CFVKRVDW+I YP I +E KIN A R VQ
Sbjct 5806 NHHEVCNIHRNEHVASGDAIMTRCLAIHDCFVKRVDWSIVYPFIDNEEKINKAGRIVQSH 5865
Query 6241 VVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSD 6300
V+KAAL +HD+GNPK I+C + W YD P ++ +E Y Y H
Sbjct 5866 VMKAALKIFNPAAIHDVGNPKGIRCA-TTPIPWFCYDRDPINNNVRCLE---YDYMVHGQ 5921
Query 6301 KFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSA 6360
+G+ LFWNCNVD YP SIVCRFDTR S L+L GC+GG+LYVN HAFHTPA+D+ A
Sbjct 5922 --MNGLMLFWNCNVDMYPEFSIVCRFDTRTRSKLSLEGCNGGALYVNNHAFHTPAYDRRA 5979
Query 6361 FVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYL 6420
F LK +PFFYY DS CE V +YVPLKS CIT+CN+GGAVC+ HA YR Y+
Sbjct 5980 FAKLKPMPFFYYDDSNCE----LVDGQPNYVPLKSNVCITKCNIGGAVCKKHAALYRAYV 6035
Query 6421 DAYNMMISAGFSLWVYKQFDTYNLWNTFTR---LQSLENVAFNVVNKGHFDGQQGEVPVS 6477
+ YNM + AGF++W + FDTY LW+ F LQSLENVAFNVV KG F G +G++P +
Sbjct 6036 EDYNMFMQAGFTIWCPQNFDTYMLWHGFVNSKALQSLENVAFNVVKKGAFTGLKGDLPTA 6095
Query 6478 IINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVI 6537
+I + + + D +F NKT+LP NVAFEL+AKR + P + IL NLGV V+
Sbjct 6096 VIADKIMVRDGPTDKCIFTNKTSLPTNVAFELYAKRKLGLTPPLTILRNLGVVATYKFVL 6155
Query 6538 WDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITE 6597
WDY+ + P T VCS TD+ + + FD + G + F ++ VLI+
Sbjct 6156 WDYEAECPFSNFTKQVCSYTDLDSE--------VVTCFDNSIAGSFERFTTTKDAVLISN 6207
Query 6598 GSVKGLQPSVGPKQASLNG--VTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEF 6655
+VKGL ++ + LN V+ +G T + Y +K V+Q+ ++Y+T R + F
Sbjct 6208 NAVKGLS-AIKLQYGFLNDLPVSTVGNKPVTWYIYVRKNGEYVEQI-DSYYTHGRTFETF 6265
Query 6656 KPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPF 6715
KPRS ME DFL + FI++Y LE Y FEH+V+GD S + +GG+HLLI + K F
Sbjct 6266 KPRSTMEEDFLSMDTTLFIQKYGLEDYGFEHVVFGDVSKTTIGGMHLLISQVRLAKMGLF 6325
Query 6716 ELEDFIP-MDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTI 6774
+++F+ DST+K+ IT A SSK VC+ +D+LLDDFV IIKS DL+VVSKVV V +
Sbjct 6326 SVQEFMTNSDSTLKSCCITYADDPSSKNVCTYMDILLDDFVTIIKSLDLNVVSKVVDVIV 6385
Query 6775 DYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATL 6834
D +MLWC++ ++TFYP+LQS++ W PG +MP LYK+QRM LE+C+L NYG L
Sbjct 6386 DCKAWRWMLWCENSQIKTFYPQLQSAE-WNPGYSMPTLYKIQRMCLERCNLYNYGAQVRL 6444
Query 6835 PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLV 6894
P GI NV KYTQLCQYLNT T+ VP+ MRV+H GA GVAPG+ VLR+WLP +LV
Sbjct 6445 PDGITTNVVKYTQLCQYLNTTTVCVPHKMRVLHLGAAGASGVAPGSTVLRRWLPDDAILV 6504
Query 6895 DSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGF 6954
D+DL D+VSDAD ++ GDC +++ +K+DL+ISD+YD TK++ EN SK+GFFTYI GF
Sbjct 6505 DNDLRDYVSDADFSVTGDCTSLYIEDKFDLLISDLYDGSTKSIDGENTSKDGFFTYINGF 6564
Query 6955 IQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGK-- 7012
I++KL+LGGS AIKITE SWN DLY+L+ F +WT F T+VN SSSE FLIG NYLG
Sbjct 6565 IKEKLSLGGSAAIKITEFSWNKDLYELIQRFEYWTVFCTSVNTSSSEGFLIGINYLGPYC 6624
Query 7013 PREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSL 7072
+ +DG +MHANYIFWRN+ + LS S+ D KF + +++LKE ++N+M++ L
Sbjct 6625 DKAIVDGNIMHANYIFWRNSTIMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVVGL 6684
Query 7073 LSKGRLIIRENNRVVISSDVLVN 7095
L KG+L+IR N +++ + LVN
Sbjct 6685 LRKGKLLIRNNGKLLNFGNHLVN 6707
Score = 54.7 bits (130), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 55/231 (24%), Positives = 105/231 (45%), Gaps = 27/231 (12%)
Query 1052 VKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA 1111
++P V+VNAAN L+H GGVA A++ T + S +Y+ ++ + G + + N+
Sbjct 1356 LEPDVLVNAANGDLRHVGGVARAIDVFTGGKLTKRSKEYLKSSKAIAPGNAVLF--ENVL 1413
Query 1112 KH--CLHVVGPNVNKGEDIQLLKSAYENFNQHE-VLLAPLLSAGIFGADPIHSLRVCVDT 1168
+H L+ VGP L + Y+ + + +L PL+S GIF
Sbjct 1414 EHLSVLNAVGPRNGDSRVEGKLCNVYKAIAKCDGKILTPLISVGIF-------------K 1460
Query 1169 VRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKI--AEIPKEEVKPFITESKPSVEQRK 1226
V+ V L K + D+ ++ F+ E+ + IP + + + + + SV K
Sbjct 1461 VKLEVSLQCLLKTVTDRDLNVFVYTDQERVTIENFFNGTIPIKVTEDTVNQKRVSVALDK 1520
Query 1227 QDDKKIKACV----EEVTTTLEETKFLTENLLLYIDINGNLH---PDSATL 1270
+++K V ++VT L + E ++ +D++ N + P++A
Sbjct 1521 TYGEQLKGTVVIKDKDVTNQLPSVSDVGEKVVKALDVDWNAYYGFPNAAAF 1571
Score = 44.7 bits (104), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 49/198 (25%), Positives = 80/198 (40%), Gaps = 14/198 (7%)
Query 1567 TIKVFTTVDNINLHTQVVDMSMTYGQQF-GPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
TI + T D +N V + TYG+Q G + DVT P S G+
Sbjct 1499 TIPIKVTEDTVNQKRVSVALDKTYGEQLKGTVVIKDKDVTNQLPSVSDVGEKVV-----K 1553
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQV--NGLTSIKWADNNCYLATALLTL 1683
L V+ YY + + SA +H +++ V N K DNNC++ L L
Sbjct 1554 ALDVDWNAYYGFPNAAAF----SASSH-DAYEFDVVTHNNFIVHKQTDNNCWVNAICLAL 1608
Query 1684 QQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDS 1743
Q+++ + P ++ + + A F ++ T G+ GD T+ L + DS
Sbjct 1609 QRLKPTWKFPGVKSLWDAFLTRKTAGFVHMLYHISGLTKGQPGDAELTLHKLVDLMSSDS 1668
Query 1744 CKRVLN-VVCKTCGQQQT 1760
V + C C + +T
Sbjct 1669 AVTVTHTTACDKCAKVET 1686
Score = 42.4 bits (98), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 71/277 (26%), Positives = 109/277 (39%), Gaps = 26/277 (9%)
Query 1656 WKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALIL 1715
+K +NG +K DNNC++ LQ + FN L D + + +FC L
Sbjct 1099 FKTTNLNGKIILKQQDNNCWINACCYQLQAFDF-FNHD-LWDGFKKDDVMPFVDFCYAAL 1156
Query 1716 AYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
G+ + ETM + A K L+ C CG ++ L E ++ T
Sbjct 1157 TLKQGDSGDAEYLLETMLNDYSTA-----KVTLSAKCG-CGVKEIVL---ERTVFKLTPL 1207
Query 1776 YEQFKKGVQIPCTCGKQATKYLVQQESPFVM----MSAPPAQYELKHGTFTCASEYTGNY 1831
+FK GV C V+ FV P +Q+ + T T + YTG
Sbjct 1208 RNEFKYGVCGDCKQINMCKFASVEGSGVFVHDRIEKQTPVSQFIV---TPTMHAVYTGTT 1264
Query 1832 QCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYT----TTIKPVTYKLDGV 1887
Q GHY I YC+DG + K ++K + +F N T T ++P D
Sbjct 1265 QSGHY-MIEDCIHDYCVDG-MGIKPRKHKFYTSTLFLNANVMTAKSKTMVEPPVPVEDKC 1322
Query 1888 VCTEIDPK--LDNYYKKDNSYFTEQPIDLVPNQPYPN 1922
V PK + +YK F + +D++ N P+
Sbjct 1323 VEDCQSPKDLILPFYKAGKVSFYQGDLDVLINFLEPD 1359
Score = 37.7 bits (86), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 59/234 (25%), Positives = 83/234 (35%), Gaps = 34/234 (15%)
Query 144 DLGDELGTDPYEDFQENWNTKHSSGVTREL-MRELNGGAYTRYVDNNFCGPDGYPLECIK 202
DL L T+P Q + +GV + ++ G YVD CG DG P+
Sbjct 71 DLKPVLLTEPSVMLQGFIVRANCNGVLEDFDLKFARTGNGAIYVDQYMCGADGKPV---- 126
Query 203 DLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKK 262
E D+ + V E+ AW T R EK QT I+ +
Sbjct 127 -----------IEGEFKDYFGDE-DVIIYEGEEYHCAWLTVRDEKPLWQQTLLTIREIQ- 173
Query 263 FDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPV-ASPNECNQMCLSTLM 321
+N + P+ P N I+ + P V+K R +Y + SP N L+T
Sbjct 174 ---YNLDIPH-KLP-NCAIREVAPPVKKNSKVVLSEEYRKLYDIFGSPFMGNGDSLNTCF 228
Query 322 KCDH---------CGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVV 366
H CG S GD+ CG K G T P +A+V
Sbjct 229 DSLHFIAATLKCPCGAESSGVGDWTGFKTACCGLHGKVK-GVTLGAVKPGDAIV 281
>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1
SV=1
Length=6629
Score = 4156 bits (10779), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2290/5157 (44%), Positives = 3140/5157 (61%), Gaps = 298/5157 (6%)
Query 2080 ANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIA 2139
A N +K+ +++G + ++ + KPN L R+ + A G + V + I
Sbjct 1626 AENFVKMGDKIGGVTMGLWRAEH----LNKPN-LERIFNIAKKAIVGSSVVTTQCGKLIG 1680
Query 2140 NYAKPFLNKVVSTTTNIVTRCLNRVC--------TNYMPYFF-TLLLQLCTFTRSTNSRI 2190
A +KV +T + +C P F TL+ L F +++ +
Sbjct 1681 KAATFIADKVGGGVVRNITDSIKGLCGITRGHFERKMSPQFLKTLMFFLFYFLKASVKSV 1740
Query 2191 KASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAAL 2250
AS T + K + ++ +I+WF+ S ++++ +
Sbjct 1741 VASYKTVLCKVVLATL----------------------LIVWFVYTS---NPVMFTGIRV 1775
Query 2251 GVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQIT 2310
+ L S C Y++ +S +V YC C VCL DSL Y +++
Sbjct 1776 ---LDFLFEGSLCGPYKDYGKDSFDVL--RYCADDFICRVCLHDKDSLHLYKHAYSVEQV 1830
Query 2311 ISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAIMQLFFSYFAVHFISNSWLMWLI 2368
A G + W Y++F F V G I Y + + NS ++
Sbjct 1831 YKD-----AASGFIFNWNWLYLVFLILFVKPVAGFVII-----CYCVKYLVLNSTVLQTG 1880
Query 2369 INLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVVDGCNSSTCMMCYKRNRATRVEC 2423
+ + + + + F + +Y W Y VH + C TC +C + R+ R E
Sbjct 1881 VCFLDWF-VQTVFSHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEV 1939
Query 2424 TTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINP 2483
+ +V G ++ +VY N G FCK HNW C NCD + +TF+S EVA +LS + KR + P
Sbjct 1940 SVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKP 1999
Query 2484 TDQSSYIVDSVTVKNGSIHLYFDKAGQ-KTYERHSLSHFVNLDNLR-ANNTKGSLPINVI 2541
T + ++VD + + ++L + A K ++ F D L+ A K +L I
Sbjct 2000 TAYAYHVVDEACLVDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQI 2059
Query 2542 VFDGKSKCEESSA------KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYV 2595
DG C SA K+A++YY+Q +C+PIL+LDQAL +
Sbjct 2060 SNDGFIVCNTQSAHALEEAKNAAIYYAQYLCKPILILDQALYEQL--------------- 2104
Query 2596 NTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVECL 2655
V K+++ + L+ +S+D + + + + S + ++ V+
Sbjct 2105 --------VVEPVSKSVIDKVCSILSSIISVDTAALNYKAGTLRDALLSITKDEEAVDMA 2156
Query 2656 KLSHQSDIEVTGDSCNNYMLTYN-KVENMTPRDLGACIDCSARHINAQVAKSHNIALIWN 2714
H D++ TGD N + +Y +TPRD G I+ A N +V + + +W
Sbjct 2157 IFCHNHDVDYTGDGFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAPPV--VWK 2214
Query 2715 VKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL--KGGKIVNN---W 2769
+ + LS+ K + SA K+ + F +T + +QV+ T K+ + K G IV+
Sbjct 2215 FSELIKLSDSCLKYLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKC 2274
Query 2770 LKQLIKVTLVF--LFVA---AIFYLITPVHVMSKHTDFSS--EIIGYKAIDGGVTRDIAS 2822
K K L+F LF A +Y+ + D +S + G+K ID GV R+I
Sbjct 2275 FKSYFKWLLIFYILFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVP 2334
Query 2823 TDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNG-DF 2881
DTCF+NK +FD ++ G Y N + CP++ AVI + G V G+PG + +G F
Sbjct 2335 EDTCFSNKFVNFDAFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMF 2390
Query 2882 LH---------FLPRVFSA--VGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPV 2930
+H ++P F+ VG YT +I F TS + +A C ++ AS P
Sbjct 2391 IHMTQTERKPWYIPTWFNREIVG---YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQ 2446
Query 2931 PYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTC 2989
YC++ N G++ + S+ P Y +G + P L V DS YCR C
Sbjct 2447 LYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQILHTPYVVKFVSDS-YCRGSVC 2505
Query 2990 ERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVA 3049
E + G CVS + +WVL ND Y S PGVFCG L+ +M + + +I +
Sbjct 2506 EYTRPGYCVSLNPQWVLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLAT 2564
Query 3050 GGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIY 3109
++ +VV + ++F+ F Y+ V L+++++ +LC+ S L + V+Y
Sbjct 2565 MFLILVVVVLIFAMVIKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLY 2624
Query 3110 LYLTFYLTNDVSFLAHIQWMVMFTPLVPFWIT---IAYIICISTKHFYWFFSNYLKRRVV 3166
Y + + + + H + F +VP W+ + +II + T F W + R +
Sbjct 2625 CYASLVTSRNTVIIMHCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKL 2684
Query 3167 FNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTS 3225
++G F ++ AA TF++ ++KL +++ ++ YL+ Y + KY+SG
Sbjct 2685 YDGNEFVGNYDLAAKSTFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQD 2741
Query 3226 YREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTC 3285
Y +A LA AL+ + NSG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+
Sbjct 2742 YLQACRAWLAYALDQYRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSY 2801
Query 3286 GTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLIRKSNHNFLVQAGN-VQLRVIGH 3343
LNGLWL D +YCPRHV+ S D N D+L +NH F V + V L V+
Sbjct 2802 RGNNLNGLWLGDTIYCPRHVLGKFSGDQWN----DVLNLANNHEFEVTTQHGVTLNVVSR 2857
Query 3344 SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSF 3403
++ VL L+ AN +TPKYKF++ G +F++ Y G+ G+Y MR N TI+ SF
Sbjct 2858 RLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASF 2917
Query 3404 LNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTI 3463
L G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G FYG +VD + AQ D +
Sbjct 2918 LAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLV 2977
Query 3464 TVNVLAWLYAAVINGD-------RWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPL 3516
T N++AWLYAA+I+ +W L T +++D+N A + P + + L
Sbjct 2978 TNNIVAWLYAAIISVKESSFSLPKW-LESTTVSVDDYNKWAGDNGFTPFSTSTA--ITKL 3034
Query 3517 SAQTGIAVLDMCASLKELL--QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKR 3574
SA TG+ D+C L+ ++ + G ILG EDE TP V Q GV QS+ R
Sbjct 3035 SAITGV---DVCKLLRTIMVKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSFVR 3091
Query 3575 TIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKH 3631
+ W +L L L +V T L F++Y L A+ I+ + VKH
Sbjct 3092 KAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFT------VKH 3144
Query 3632 KHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRIMTWLDMV--DTSL-------- 3674
A++ FLLP+L TV A +Y + + V+ + W D V DT +
Sbjct 3145 VMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPLV 3204
Query 3675 --SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAI 3731
+ FK ++ C M + LL+L + ++T N LT + GN
Sbjct 3205 LYTAFKCVQGCYMNSFNTSLLMLYQFVKL----GFVIYTSSNTLTAYTE---GN------ 3251
Query 3732 SMWALII-----SVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFL 3786
W L +V +N S +F+ + +M + YC ++ L +M V C +
Sbjct 3252 --WELFFELVHTTVLANVSSNSLIGLFVFKCAKWM-LYYCNATYLNNYVLMAVM-VNC-I 3306
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G
Sbjct 3307 GWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQG 3366
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG + +ATVQ+K+SDVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E
Sbjct 3367 IGGDRVLPIATVQAKLSDVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGE 3426
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
+ ++ +L L + +D+++ C+++L LQ++ EFS +PSYA + A+ YE+
Sbjct 3427 CMDNLLGMLITLFCIDSTIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEK 3486
Query 3967 AVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKR 4022
+ + G ++ L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+R
Sbjct 3487 VLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRR 3546
Query 4023 AKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKN 4082
AK+ S++ +LF+ML+K+D++ LN + + A G VPL +P+ + KL +VIPD T+
Sbjct 3547 AKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVK 3606
Query 4083 TCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-----NSPNLAWPLIVTALRANSA- 4136
+G TY++ +W I V+DAD + + + N+AWPL V R
Sbjct 3607 CVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNK 3666
Query 4137 --VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
V LQNNEL P ++ +C AG Q C+ ++ YY G V A+ S +LK A
Sbjct 3667 VDVVLQNNELMPHGVKTKACVAGVDQAHCSVESK-CYYTNISGNSVVAAITSSNPNLKVA 3725
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
F G IY +L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+
Sbjct 3726 SFLNEAGN-QIYVDLDPPCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQS 3784
Query 4255 -GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
G+ TE +LS C+FAVD A Y Y+A+G QP+ NCVKML H G+G AIT P
Sbjct 3785 KGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPS 3844
Query 4314 ANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
DQ+S+GGAS CLYCR HI HP N G C KG +VQIPTT DPVGF L+N V
Sbjct 3845 PTPDQDSYGGASVCLYCRAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKV 3903
Query 4370 CTVCGMWKGYGCSCDQLREPM--LQSADAQS-----FLNRVCGVSAARLTPCGTGTSTDV 4422
CTVC W GYGC CD LR+P +QS S +LNRV G S ARL P +G DV
Sbjct 3904 CTVCQCWIGYGCQCDSLRQPKSSVQSVAGASDFDKNYLNRVRGSSEARLIPLASGCDPDV 3963
Query 4423 VYRAFDIYNDKVAGFAKFLKTNCCRFQE--KDEDDNL--IDSYFVVKRHTFSNYQHEETI 4478
V RAFD+ N + AG + LK NC RFQE ED NL +DSYFVVK+ T SNY+HE++
Sbjct 3964 VKRAFDVCNKESAGMFQNLKRNCARFQELRDTEDGNLEYLDSYFVVKQTTPSNYEHEKSC 4023
Query 4479 YNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEIL 4538
Y LK A HDFF F + + +ISRQRLTKYTM D YALRHFD +C+ LKEIL
Sbjct 4024 YEDLKS-EVTADHDFFVFNKN---IYNISRQRLTKYTMMDFCYALRHFDPKDCEVLKEIL 4079
Query 4539 VTYNCCDD---DYFNK-KDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIV 4594
VTY C +D +F + KDWYD +EN + A +G VR+ALL ++F + M G V
Sbjct 4080 VTYGCIEDYHPKWFEENKDWYDPIENSKYYVMLAKMGPIVRRALLNAIEFGNLMVEKGYV 4139
Query 4595 GVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLT 4654
GV+TLDNQDLNG +YDFGDF +T PG+GVPV D+YYS +MPI+ +T AL E + + D+
Sbjct 4140 GVITLDNQDLNGKFYDFGDFQKTAPGAGVPVFDTYYSYMMPIIAMTDALAPERYFEYDVH 4199
Query 4655 KPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFP 4714
K Y +DLLKYD+TEE+ +LF +YFKYWDQ YHPNC +C DDRC++HCANFN+LFST+ P
Sbjct 4200 KGYKSYDLLKYDYTEEKQELFQKYFKYWDQEYHPNCRDCSDDRCLIHCANFNILFSTLIP 4259
Query 4715 PTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHA 4774
TSFG L RK+FVDGVPF+ + GYH +ELGV+ NQD + S++ +L+ + DPA+
Sbjct 4260 QTSFGNLCRKVFVDGVPFIATCGYHSKELGVIMNQDNTMSFSKMGLSQLMQFVGDPALLV 4319
Query 4775 ASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFF 4834
+ N L+D RT+CFSV ALT+ + QTVKPG+FNKDFYDFA G FKEGSS+ LKHFF+
Sbjct 4320 GTSNNLVDLRTSCFSVCALTSGITHQTVKPGHFNKDFYDFAEKAGMFKEGSSIPLKHFFY 4379
Query 4835 AQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSA 4894
Q GNAAI+DYDYYRYN PTM DI QLLF +EV KYF+CY+GGCI A+QV+VNNLDKSA
Sbjct 4380 PQTGNAAINDYDYYRYNRPTMFDICQLLFCLEVTSKYFECYEGGCIPASQVVVNNLDKSA 4439
Query 4895 GFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSI 4954
G+PFNK+GKARLYY+ MS E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI
Sbjct 4440 GYPFNKFGKARLYYE-MSLEEQDQLFEITKKNVLPTITQMNLKYAISAKNRARTVAGVSI 4498
Query 4955 CSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKC 5014
STMTNRQFHQK+LKSI TR A+VVIGT+KFYGGW NML+ + VE+P LMGWDYPKC
Sbjct 4499 LSTMTNRQFHQKILKSIVNTRNASVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKC 4558
Query 5015 DRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSS 5074
DRAMPN+LRI ASLVLARKHT CCS S R YRL NECAQVLSE V+ G +YVKPGGTSS
Sbjct 4559 DRAMPNLLRIAASLVLARKHTNCCSWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSS 4618
Query 5075 GDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFV 5134
GDATTAYANSVFNI QA +ANV LLS I +++LQ+ LY+ +YR + D FV
Sbjct 4619 GDATTAYANSVFNIIQATSANVARLLSVITRDIVYDNIKSLQYELYQQVYRRVNFDPAFV 4678
Query 5135 NEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTE 5194
+FY+YL K+FS+MILSDD VVC+N+T A QGLVA I F+ VLYYQNNVFM+++KCW E
Sbjct 4679 EKFYSYLCKNFSLMILSDDGVVCYNNTLAKQGLVADISGFREVLYYQNNVFMADSKCWVE 4738
Query 5195 TDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSL 5254
DL KGPHEFCSQHTMLV+ + YLPYPDPSRILGA FVDD+ KT+ ++ER+++L
Sbjct 4739 PDLEKGPHEFCSQHTMLVEVDGEPKYLPYPDPSRILGACVFVDDVDKTEPVAVMERYIAL 4798
Query 5255 AIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYE 5314
AIDAYPL H N+EY VF + L YIRKL+ EL+ +ML YS ++ D S++WE EFYE
Sbjct 4799 AIDAYPLVHHENEEYKKVFFVLLAYIRKLYQELSQNMLMDYSFVMDIDKGSKFWEQEFYE 4858
Query 5315 AMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVC 5374
MY T LQ+ G CV+CNSQT LRCG CIR+PFLCCKCCYDHV+ T HK VLS+NPY+C
Sbjct 4859 NMYRAPTTLQSCGVCVVCNSQTILRCGNCIRKPFLCCKCCYDHVMHTDHKNVLSINPYIC 4918
Query 5375 NAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIA 5434
+ GC DVT+LYLGGMSY+C +HKP +S PL +NG VFG+Y+ C GS+NV DFN +A
Sbjct 4919 SQLGCGEADVTKLYLGGMSYFCGNHKPKLSIPLVSNGTVFGIYRANCAGSENVDDFNQLA 4978
Query 5435 TCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVG 5494
T +W+ YILAN C++ L+ FAAET+KATEE K + A VREV SDREL LSWE G
Sbjct 4979 TTNWSIVEPYILANRCSDSLRRFAAETVKATEELHKQQFASAEVREVFSDRELILSWEPG 5038
Query 5495 KPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSH 5554
K RPPLNRNYVFTGY T+ SKVQ+G++TFEKG+ D V Y+ T+T KL+VGD FVLTSH
Sbjct 5039 KTRPPLNRNYVFTGYHFTRTSKVQLGDFTFEKGEGKDVVYYKATSTAKLSVGDIFVLTSH 5098
Query 5555 TVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSH 5614
V+ L APTL PQ+ + R L P + + + F +N+ Y VG QK +T+QGPPG+GKSH
Sbjct 5099 NVVSLVAPTLCPQQTFSRFVNLRPNVMVPECFVNNIPLYHLVGKQKRTTVQGPPGSGKSH 5158
Query 5615 FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNS 5674
FAIGLA+Y+ SAR+V+TACSHAAVDALCEKA K+L +D C+RI+P R V+CF KFK N
Sbjct 5159 FAIGLAVYFSSARVVFTACSHAAVDALCEKAFKFLKVDDCTRIVPQRTTVDCFSKFKAND 5218
Query 5675 TLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRT 5734
T ++Y+F T+NALPE + DI++ DE+SM TNY+LS +N ++ ++ VY+GDPAQLPAPRT
Sbjct 5219 TGKKYIFSTINALPEVSCDILLVDEVSMLTNYELSFINGKINYQYVVYVGDPAQLPAPRT 5278
Query 5735 LLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ 5794
LL G+L P+ +N V LM + PD+FL C RCP EIVDTVS LVYD K A+ +S +
Sbjct 5279 LLN-GSLSPKDYNVVTNLMVCVKPDIFLAKCYRCPKEIVDTVSTLVYDGKFIANNPESRE 5337
Query 5795 CFKMFYKGV---ITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILG 5851
CFK+ + H+ SA N Q+ V++F+ RN WR+A+FISPYN+ N A ++LG
Sbjct 5338 CFKVIVNNGNSDVGHESGSAYNTTQLEFVKDFVCRNKQWREAIFISPYNAMNQRAYRMLG 5397
Query 5852 LPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRD-LYDKLQ 5910
L QTVDSSQGSEYDYVIF T ++ H+ N+NRFNVA+TRAK GIL +M RD LY L+
Sbjct 5398 LNVQTVDSSQGSEYDYVIFCVTADSQHALNINRFNVALTRAKRGILVVMRQRDELYSALK 5457
Query 5911 FTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGI 5970
FT L+ + +LQ TGLFK C+K +G+HP A T ++ +K + +
Sbjct 5458 FTELD----SETSLQG---TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNV 5510
Query 5971 P--KDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGT 6028
++TY+ LIS++GFKM+ V G NMFITR+EAIR+VR W+GFDVE HA +GT
Sbjct 5511 EAGSEITYKHLISLLGFKMSVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGT 5570
Query 6029 NLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVR 6088
NLP Q+GFSTG + V P G VDT +F V++K PPG+QF HL L PW+V+R
Sbjct 5571 NLPFQVGFSTGADFVVTPEGLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIR 5630
Query 6089 IKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDT 6148
+IVQML+D L N+SD VVFV W HG ELT+++YFVKIG E+ C C RAT F++ +
Sbjct 5631 PRIVQMLADNLCNVSDCVVFVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQA 5689
Query 6149 YACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVH 6208
YACW H +GFD+VYNP ++D+QQWG++GNLQ NHDL+C VHG+AHVAS DAIMTRCLA++
Sbjct 5690 YACWKHCLGFDFVYNPLLVDIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAIN 5749
Query 6209 ECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQ 6268
F + V+W + YP I +E ++N++CR +Q M + A + A K V++DIGNPK IKCV +
Sbjct 5750 NAFCQDVNWDLTYPHIANEDEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRR 5809
Query 6269 ADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDT 6328
DV ++FYD P + E Y Y H DKF DG+C+FWNCNVD YP NS+VCR+DT
Sbjct 5810 GDVNFRFYDKNPIVRNVKQFE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDT 5866
Query 6329 RVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDI 6388
R LS NLPGC+GGSLYVNKHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+
Sbjct 5867 RNLSVFNLPGCNGGSLYVNKHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ- 5925
Query 6389 DYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF 6448
D V L + CIT+CN+GGAVC+ HA Y ++ +YN ++AGF+ WV + + YNLW +F
Sbjct 5926 DLVSLATKDCITKCNIGGAVCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSF 5985
Query 6449 TRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFE 6508
+ LQS++N+A+N+ GH+D GE+P I + V+ GV+ +F N+TTLP +VAFE
Sbjct 5986 SALQSIDNIAYNMYKGGHYDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFE 6045
Query 6509 LWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETIC 6568
L+AKRNI+ +P +IL LGVD+ VIWDY P + +T+ VC+ TDI
Sbjct 6046 LYAKRNIRTLPNNRILKGLGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEPN------ 6099
Query 6569 APLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQ 6627
L V +D R G F A N VL++ K P + NG+ L A
Sbjct 6100 -GLVVLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---N 6154
Query 6628 FNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHI 6687
YK+V+G LP T TQ R+ + F+PRS +E DFL ++ + F+ERY + +HI
Sbjct 6155 LYVYKRVNGAFVTLPNTINTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHI 6213
Query 6688 VYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTV-KNYFITDAQTGSSKCVCSV 6746
+YG+ QLGGLH +IG+ + + + + DS V +NYF+ + GS K VC+V
Sbjct 6214 LYGEVDKPQLGGLHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVL-SDNGSYKQVCTV 6272
Query 6747 IDLLLDDFV----EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQA 6802
+DLLLDDF+ I+K + SKVV V+IDY I+FM W +DG ++T YP+LQS A
Sbjct 6273 VDLLLDDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQS--A 6329
Query 6803 WQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYN 6862
W G MP LYK+Q ++E C++ NYG TLP GI+MNVAKYTQLCQYL+ T+ VP+N
Sbjct 6330 WTCGYNMPELYKVQNCVMEPCNIPNYGVGITLPSGILMNVAKYTQLCQYLSKTTICVPHN 6389
Query 6863 MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW 6922
MRV+HFGAGSDKGVAPG+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC +T +K+
Sbjct 6390 MRVMHFGAGSDKGVAPGSTVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYNTEHKF 6449
Query 6923 DLIISDMY---DPKTKNV-TKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADL 6978
DL+ISDMY D K K+ N+ + F Y+ F++ LALGGS A+K+TE SW+ L
Sbjct 6450 DLVISDMYTDNDSKRKHEGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSWHEVL 6509
Query 6979 YKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPRE-QIDGYVMHANYIFWRNTNPIQL 7037
Y + AWWT F T VNASSSEAFLIG NYLG + ++ G +HANYIFWRN N +Q
Sbjct 6510 YDIAQDCAWWTMFCTAVNASSSEAFLIGVNYLGASEKVKVSGKTLHANYIFWRNCNYLQT 6569
Query 7038 SSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLV 7094
S+YS+FD++KF L+L+ T V++LK Q D++ +L+ G+L++R+ +SD V
Sbjct 6570 SAYSIFDVAKFDLRLKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 6626
Score = 68.2 bits (165), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 57/243 (23%), Positives = 107/243 (44%), Gaps = 15/243 (6%)
Query 1570 VFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRV 1629
++ T D + + V+ + GQ FG Y V + + + YV D ++
Sbjct 1180 IYLTEDGVKYRSIVLKPGDSLGQ-FGQVYAKNKIV--FTADDVEDKEILYVPTTDKSI-- 1234
Query 1630 EAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELK 1689
EYY ++ Y+ L +KW + ++W D NC++++A++ LQ +++
Sbjct 1235 --LEYYGLDAQKYV-IYLQTL--AQKWNVQYRDNFLILEWRDGNCWISSAIVLLQAAKIR 1289
Query 1690 FNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLN 1749
F L +A+ + G+ +F A A C VG+ D ++ L +H + D L
Sbjct 1290 FK-GFLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFSDANWLLANLAEHFDADYTNAFLK 1348
Query 1750 --VVCKTCGQQQTTLKGVEA-VMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVM 1806
V C CG + L+G+EA + + + FK TCG T +++ P+++
Sbjct 1349 KRVSC-NCGIKSYELRGLEACIQPVRATNLLHFKTQYSNCPTCGANNTDEVIEASLPYLL 1407
Query 1807 MSA 1809
+ A
Sbjct 1408 LFA 1410
Score = 53.9 bits (128), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 53/192 (28%), Positives = 87/192 (45%), Gaps = 20/192 (10%)
Query 985 QQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV---QTIEVNSFSGYLKLTDNVYIK 1041
++ V Q+DG++ Q + I V+PQ E + T E F Y ++ +
Sbjct 971 EEVVSQKDGAQIKQ----EPIQVVKPQREKKAKKFKVKPATCEKPKFLEYKTCVGDLTVV 1026
Query 1042 NADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGG 1101
A ++E K+ +VNAAN ++ HG GVA A+ +DY+ +GP +
Sbjct 1027 IAKALDEFKEF---CIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ--- 1080
Query 1102 SCVLSGHNLAKHCL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGADP 1158
V C+ +VVGP + L +AY+N V+ + P+LS GIFG D
Sbjct 1081 RLVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGVD- 1139
Query 1159 IHSLRVCVDTVR 1170
++ +D +R
Sbjct 1140 ---FKMSIDAMR 1148
>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep
PE=3 SV=1
Length=6629
Score = 4155 bits (10775), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2290/5157 (44%), Positives = 3139/5157 (61%), Gaps = 298/5157 (6%)
Query 2080 ANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIA 2139
A N +K+ +++G + ++ + KPN L R+ + A G + V + I
Sbjct 1626 AENFVKMGDKIGGVTMGLWRAEH----LNKPN-LERIFNIAKKAIVGSSVVTTQCGKLIG 1680
Query 2140 NYAKPFLNKVVSTTTNIVTRCLNRVC--------TNYMPYFF-TLLLQLCTFTRSTNSRI 2190
A +KV +T + +C P F TL+ L F +++ +
Sbjct 1681 KAATFIADKVGGGVVRNITDSIKGLCGITRGHFERKMSPQFLKTLMFFLFYFLKASVKSV 1740
Query 2191 KASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAAL 2250
AS T + K + ++ +I+WF+ S ++++ +
Sbjct 1741 VASYKTVLCKVVLATL----------------------LIVWFVYTS---NPVMFTGIRV 1775
Query 2251 GVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQIT 2310
+ L S C Y++ +S +V YC C VCL DSL Y +++
Sbjct 1776 ---LDFLFEGSLCGPYKDYGKDSFDVL--RYCADDFICRVCLHDKDSLHLYKHAYSVEQV 1830
Query 2311 ISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAIMQLFFSYFAVHFISNSWLMWLI 2368
A G + W Y++F F V G I Y + + NS ++
Sbjct 1831 YKD-----AASGFIFNWNWLYLVFLILFVKPVAGFVII-----CYCVKYLVLNSTVLQTG 1880
Query 2369 INLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVVDGCNSSTCMMCYKRNRATRVEC 2423
+ + + + + F + +Y W Y VH + C TC +C + R+ R E
Sbjct 1881 VCFLDWF-VQTVFSHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEV 1939
Query 2424 TTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINP 2483
+ +V G ++ +VY N G FCK HNW C NCD + +TF+S EVA +LS + KR + P
Sbjct 1940 SVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKP 1999
Query 2484 TDQSSYIVDSVTVKNGSIHLYFDKAGQ-KTYERHSLSHFVNLDNLR-ANNTKGSLPINVI 2541
T + ++VD + + ++L + A K ++ F D L+ A K +L I
Sbjct 2000 TAYAYHVVDEACLVDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQI 2059
Query 2542 VFDGKSKCEESSA------KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYV 2595
DG C SA K+A++YY+Q +C+PIL+LDQAL +
Sbjct 2060 SNDGFIVCNTQSAHALEEAKNAAIYYAQYLCKPILILDQALYEQL--------------- 2104
Query 2596 NTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVECL 2655
V K+++ + L+ +S+D + + + + S + ++ V+
Sbjct 2105 --------VVEPVSKSVIDKVCSILSSIISVDTAALNYKAGTLRDALLSITKDEEAVDMA 2156
Query 2656 KLSHQSDIEVTGDSCNNYMLTYN-KVENMTPRDLGACIDCSARHINAQVAKSHNIALIWN 2714
H D++ TGD N + +Y +TPRD G I+ A N +V + + +W
Sbjct 2157 IFCHNHDVDYTGDGFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAPPV--VWK 2214
Query 2715 VKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL--KGGKIVNN---W 2769
+ + LS+ K + SA K+ + F +T + +QV+ T K+ + K G IV+
Sbjct 2215 FSELIKLSDSCLKYLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKC 2274
Query 2770 LKQLIKVTLVF--LFVA---AIFYLITPVHVMSKHTDFSS--EIIGYKAIDGGVTRDIAS 2822
K K L+F LF A +Y+ + D +S + G+K ID GV R+I
Sbjct 2275 FKSYFKWLLIFYILFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVP 2334
Query 2823 TDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNG-DF 2881
DTCF+NK +FD ++ G Y N + CP++ AVI + G V G+PG + +G F
Sbjct 2335 EDTCFSNKFVNFDAFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMF 2390
Query 2882 LH---------FLPRVFSA--VGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPV 2930
+H ++P F+ VG YT +I F TS + +A C ++ AS P
Sbjct 2391 IHMTQTERKPWYIPTWFNREIVG---YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQ 2446
Query 2931 PYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTC 2989
YC++ N G++ + S+ P Y +G + P L V DS YCR C
Sbjct 2447 LYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQILHTPYVVKFVSDS-YCRGSVC 2505
Query 2990 ERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVA 3049
E + G CVS + +WVL ND Y S PGVFCG L+ +M + + +I +
Sbjct 2506 EYTRPGYCVSLNPQWVLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLAT 2564
Query 3050 GGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIY 3109
++ +VV + ++F+ F Y+ V L+++++ +LC+ S L + V+Y
Sbjct 2565 MFLILVVVVLIFAMVIKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLY 2624
Query 3110 LYLTFYLTNDVSFLAHIQWMVMFTPLVPFWIT---IAYIICISTKHFYWFFSNYLKRRVV 3166
Y + + + + H + F +VP W+ + +II + T F W + R +
Sbjct 2625 CYASLVTSRNTVIIMHCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKL 2684
Query 3167 FNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTS 3225
++G F ++ AA TF++ ++KL +++ ++ YL+ Y + KY+SG
Sbjct 2685 YDGNEFVGNYDLAAKSTFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQD 2741
Query 3226 YREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTC 3285
Y +A LA AL+ + NSG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+
Sbjct 2742 YLQACRAWLAYALDQYRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSY 2801
Query 3286 GTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLIRKSNHNFLVQAGN-VQLRVIGH 3343
LNGLWL D +YCPRHV+ S D N D+L +NH F V + V L V+
Sbjct 2802 RGNNLNGLWLGDTIYCPRHVLGKFSGDQWN----DVLNLANNHEFEVTTQHGVTLNVVSR 2857
Query 3344 SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSF 3403
++ VL L+ AN +TPKYKF++ G +F++ Y G+ G+Y MR N TI+ SF
Sbjct 2858 RLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASF 2917
Query 3404 LNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTI 3463
L G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G FYG +VD + AQ D +
Sbjct 2918 LAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLV 2977
Query 3464 TVNVLAWLYAAVINGD-------RWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPL 3516
T N++AWLYAA+I+ +W L T +++D+N A + P + + L
Sbjct 2978 TNNIVAWLYAAIISVKESSFSLPKW-LESTTVSVDDYNKWAGDNGFTPFSTSTA--ITKL 3034
Query 3517 SAQTGIAVLDMCASLKELL--QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKR 3574
SA TG+ D+C L+ ++ + G ILG EDE TP V Q GV QS+ R
Sbjct 3035 SAITGV---DVCKLLRTIMVKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSFVR 3091
Query 3575 TIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKH 3631
+ W +L L L +V T L F++Y L A+ I+ + VKH
Sbjct 3092 KAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFT------VKH 3144
Query 3632 KHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRIMTWLDMV--DTSL-------- 3674
A++ FLLP+L TV A +Y + + V+ + W D V DT +
Sbjct 3145 VMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPLV 3204
Query 3675 --SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAI 3731
+ FK ++ C M + LL+L + ++T N LT + GN
Sbjct 3205 LYTAFKCVQGCYMNSFNTSLLMLYQFVKL----GFVIYTSSNTLTAYTE---GN------ 3251
Query 3732 SMWALII-----SVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFL 3786
W L +V +N S +F+ + +M + YC ++ L +M V C +
Sbjct 3252 --WELFFELVHTTVLANVSSNSLIGLFVFKCAKWM-LYYCNATYLNNYVLMAVM-VNC-I 3306
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G
Sbjct 3307 GWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQG 3366
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG + +ATVQ+K+SDVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E
Sbjct 3367 IGGDRVLPIATVQAKLSDVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGE 3426
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
+ ++ +L L + +D+++ C+++L LQ++ EFS +PSYA + A+ YE+
Sbjct 3427 CMDNLLGMLITLFCIDSTIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEK 3486
Query 3967 AVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKR 4022
+ + G ++ L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+R
Sbjct 3487 VLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRR 3546
Query 4023 AKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKN 4082
AK+ S++ +LF+ML+K+D++ LN + + A G VPL +P+ + KL +VIPD T+
Sbjct 3547 AKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVK 3606
Query 4083 TCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-----NSPNLAWPLIVTALRANSA- 4136
+G TY++ +W I V+DAD + + + N+AWPL V R
Sbjct 3607 CVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNK 3666
Query 4137 --VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
V LQNNEL P ++ +C AG Q C+ ++ YY G V A+ S +LK A
Sbjct 3667 VDVVLQNNELMPHGVKTKACVAGVDQAHCSVESK-CYYTNISGNSVVAAITSSNPNLKVA 3725
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
F G IY +L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+
Sbjct 3726 SFLNEAGN-QIYVDLDPPCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQS 3784
Query 4255 -GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
G+ TE +LS C+FAVD A Y Y+A+G QP+ NCVKML H G+G AIT P
Sbjct 3785 KGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPS 3844
Query 4314 ANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
DQ+S+GGAS CLYCR HI HP N G C KG +VQIPTT DPVGF L+N V
Sbjct 3845 PTPDQDSYGGASVCLYCRAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKV 3903
Query 4370 CTVCGMWKGYGCSCDQLREPM--LQSADAQS-----FLNRVCGVSAARLTPCGTGTSTDV 4422
CTVC W GYGC CD LR+P +QS S +LNRV G S ARL P +G DV
Sbjct 3904 CTVCQCWIGYGCQCDSLRQPKSSVQSVAGASDFDKNYLNRVRGSSEARLIPLASGCDPDV 3963
Query 4423 VYRAFDIYNDKVAGFAKFLKTNCCRFQE--KDEDDNL--IDSYFVVKRHTFSNYQHEETI 4478
V RAFD+ N + AG + LK NC RFQE ED NL +DSYFVVK+ T SNY+HE++
Sbjct 3964 VKRAFDVCNKESAGMFQNLKRNCARFQELRDTEDGNLEYLDSYFVVKQTTPSNYEHEKSC 4023
Query 4479 YNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEIL 4538
Y LK A HDFF F + + +ISRQRLTKYTM D YALRHFD +C+ LKEIL
Sbjct 4024 YEDLKS-EVTADHDFFVFNKN---IYNISRQRLTKYTMMDFCYALRHFDPKDCEVLKEIL 4079
Query 4539 VTYNCCDD---DYFNK-KDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIV 4594
VTY C +D +F + KDWYD +EN + A +G VR+ALL ++F + M G V
Sbjct 4080 VTYGCIEDYHPKWFEENKDWYDPIENSKYYVMLAKMGPIVRRALLNAIEFGNLMVEKGYV 4139
Query 4595 GVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLT 4654
GV+TLDNQDLNG +YDFGDF +T PG+GVPV D+YYS +MPI+ +T AL E + + D+
Sbjct 4140 GVITLDNQDLNGKFYDFGDFQKTAPGAGVPVFDTYYSYMMPIIAMTDALAPERYFEYDVH 4199
Query 4655 KPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFP 4714
K Y +DLLKYD+TEE+ +LF +YFKYWDQ YHPNC +C DDRC++HCANFN+LFST+ P
Sbjct 4200 KGYKSYDLLKYDYTEEKQELFQKYFKYWDQEYHPNCRDCSDDRCLIHCANFNILFSTLIP 4259
Query 4715 PTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHA 4774
TSFG L RK+FVDGVPF+ + GYH +ELGV+ NQD + S++ +L+ + DPA+
Sbjct 4260 QTSFGNLCRKVFVDGVPFIATCGYHSKELGVIMNQDNTMSFSKMGLSQLMQFVGDPALLV 4319
Query 4775 ASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFF 4834
+ N L+D RT+CFSV ALT+ + QTVKPG+FNKDFYDFA G FKEGSS+ LKHFF+
Sbjct 4320 GTSNNLVDLRTSCFSVCALTSGITHQTVKPGHFNKDFYDFAEKAGMFKEGSSIPLKHFFY 4379
Query 4835 AQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSA 4894
Q GNAAI+DYDYYRYN PTM DI QLLF +EV KYF+CY+GGCI A+QV+VNNLDKSA
Sbjct 4380 PQTGNAAINDYDYYRYNRPTMFDICQLLFCLEVTSKYFECYEGGCIPASQVVVNNLDKSA 4439
Query 4895 GFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSI 4954
G+PFNK+GKARLYY+ MS E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI
Sbjct 4440 GYPFNKFGKARLYYE-MSLEEQDQLFEITKKNVLPTITQMNLKYAISAKNRARTVAGVSI 4498
Query 4955 CSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKC 5014
STMTNRQFHQK+LKSI TR A+VVIGT+KFYGGW NML+ + VE+P LMGWDYPKC
Sbjct 4499 LSTMTNRQFHQKILKSIVNTRNASVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKC 4558
Query 5015 DRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSS 5074
DRAMPN+LRI ASLVLARKHT CCS S R YRL NECAQVLSE V+ G +YVKPGGTSS
Sbjct 4559 DRAMPNLLRIAASLVLARKHTNCCSWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSS 4618
Query 5075 GDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFV 5134
GDATTAYANSVFNI QA +ANV LLS I +++LQ+ LY+ +YR + D FV
Sbjct 4619 GDATTAYANSVFNIIQATSANVARLLSVITRDIVYDNIKSLQYELYQQVYRRVNFDPAFV 4678
Query 5135 NEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTE 5194
+FY+YL K+FS+MILSDD VVC+N+T A QGLVA I F+ VLYYQNNVFM+++KCW E
Sbjct 4679 EKFYSYLCKNFSLMILSDDGVVCYNNTLAKQGLVADISGFREVLYYQNNVFMADSKCWVE 4738
Query 5195 TDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSL 5254
DL KGPHEFCSQHTMLV+ + YLPYPDPSRILGA FVDD+ KT+ ++ER+++L
Sbjct 4739 PDLEKGPHEFCSQHTMLVEVDGEPKYLPYPDPSRILGACVFVDDVDKTEPVAVMERYIAL 4798
Query 5255 AIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYE 5314
AIDAYPL H N+EY VF + L YIRKL+ EL+ +ML YS ++ D S++WE EFYE
Sbjct 4799 AIDAYPLVHHENEEYKKVFFVLLAYIRKLYQELSQNMLMDYSFVMDIDKGSKFWEQEFYE 4858
Query 5315 AMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVC 5374
MY T LQ+ G CV+CNSQT LRCG CIR+PFLCCKCCYDHV+ T HK VLS+NPY+C
Sbjct 4859 NMYRAPTTLQSCGVCVVCNSQTILRCGNCIRKPFLCCKCCYDHVMHTDHKNVLSINPYIC 4918
Query 5375 NAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIA 5434
+ GC DVT+LYLGGMSY+C +HKP +S PL +NG VFG+Y+ C GS+NV DFN +A
Sbjct 4919 SQLGCGEADVTKLYLGGMSYFCGNHKPKLSIPLVSNGTVFGIYRANCAGSENVDDFNQLA 4978
Query 5435 TCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVG 5494
T +W+ YILAN C++ L+ FAAET+KATEE K + A VREV SDREL LSWE G
Sbjct 4979 TTNWSIVEPYILANRCSDSLRRFAAETVKATEELHKQQFASAEVREVFSDRELILSWEPG 5038
Query 5495 KPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSH 5554
K RPPLNRNYVFTGY T+ SKVQ+G++TFEKG+ D V Y+ T+T KL+VGD FVLTSH
Sbjct 5039 KTRPPLNRNYVFTGYHFTRTSKVQLGDFTFEKGEGKDVVYYKATSTAKLSVGDIFVLTSH 5098
Query 5555 TVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSH 5614
V+ L APTL PQ+ + R L P + + + F +N+ Y VG QK +T+QGPPG+GKSH
Sbjct 5099 NVVSLVAPTLCPQQTFSRFVNLRPNVMVPECFVNNIPLYHLVGKQKRTTVQGPPGSGKSH 5158
Query 5615 FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNS 5674
FAIGLA+Y+ SAR+V+TACSHAAVDALCEKA K+L +D C+RI+P R V+CF KFK N
Sbjct 5159 FAIGLAVYFSSARVVFTACSHAAVDALCEKAFKFLKVDDCTRIVPQRTTVDCFSKFKAND 5218
Query 5675 TLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRT 5734
T ++Y+F T+NALPE + DI++ DE+SM TNY+LS +N ++ ++ VY+GDPAQLPAPRT
Sbjct 5219 TGKKYIFSTINALPEVSCDILLVDEVSMLTNYELSFINGKINYQYVVYVGDPAQLPAPRT 5278
Query 5735 LLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ 5794
LL G+L P+ +N V LM + PD+FL C RCP EIVDTVS LVYD K A+ +S +
Sbjct 5279 LLN-GSLSPKDYNVVTNLMVCVKPDIFLAKCYRCPKEIVDTVSTLVYDGKFIANNPESRE 5337
Query 5795 CFKMFYKGV---ITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILG 5851
CFK+ + H+ SA N Q+ V++F+ RN WR+A+FISPYN+ N A ++LG
Sbjct 5338 CFKVIVNNGNSDVGHESGSAYNTTQLEFVKDFVCRNKQWREAIFISPYNAMNQRAYRMLG 5397
Query 5852 LPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRD-LYDKLQ 5910
L QTVDSSQGSEYDYVIF T ++ H+ N+NRFNVA+TRAK GIL +M RD LY L+
Sbjct 5398 LNVQTVDSSQGSEYDYVIFCVTADSQHALNINRFNVALTRAKRGILVVMRQRDELYSALK 5457
Query 5911 FTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGI 5970
FT L+ + +LQ TGLFK C+K +G+HP A T ++ +K + +
Sbjct 5458 FTELD----SETSLQG---TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNV 5510
Query 5971 P--KDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGT 6028
++TY+ LIS++GFKM+ V G NMFITR+EAIR+VR W+GFDVE HA +GT
Sbjct 5511 EAGSEITYKHLISLLGFKMSVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGT 5570
Query 6029 NLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVR 6088
NLP Q+GFSTG + V P G VDT +F V++K PPG+QF HL L PW+V+R
Sbjct 5571 NLPFQVGFSTGADFVVTPEGLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIR 5630
Query 6089 IKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDT 6148
+IVQML+D L N+SD VVFV W HG ELT+++YFVKIG E+ C C RAT F++ +
Sbjct 5631 PRIVQMLADNLCNVSDCVVFVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQA 5689
Query 6149 YACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVH 6208
YACW H +GFD+VYNP ++D+QQWG++GNLQ NHDL+C VHG+AHVAS DAIMTRCLA++
Sbjct 5690 YACWKHCLGFDFVYNPLLVDIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAIN 5749
Query 6209 ECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQ 6268
F + V+W + YP I +E ++N++CR +Q M + A + A K V++DIGNPK IKCV +
Sbjct 5750 NAFCQDVNWDLTYPHIANEDEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRR 5809
Query 6269 ADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDT 6328
DV ++FYD P + E Y Y H DKF DG+C+FWNCNVD YP NS+VCR+DT
Sbjct 5810 GDVNFRFYDKNPIVRNVKQFE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDT 5866
Query 6329 RVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDI 6388
R LS NLPGC+GGSLYVNKHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+
Sbjct 5867 RNLSVFNLPGCNGGSLYVNKHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ- 5925
Query 6389 DYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF 6448
D V L + CIT+CN+GGAVC+ HA Y ++ +YN ++AGF+ WV + + YNLW +F
Sbjct 5926 DLVSLATKDCITKCNIGGAVCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSF 5985
Query 6449 TRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFE 6508
+ LQS++N+A+N+ GH+D GE+P I + V+ GV+ +F N+TTLP +VAFE
Sbjct 5986 SALQSIDNIAYNMYKGGHYDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFE 6045
Query 6509 LWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETIC 6568
L+AKRNI+ +P +IL LGVD+ VIWDY P + +T+ VC+ TDI
Sbjct 6046 LYAKRNIRTLPNNRILKGLGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEPN------ 6099
Query 6569 APLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQ 6627
L V +D R G F A N VL++ K P + NG+ L A
Sbjct 6100 -GLVVLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---N 6154
Query 6628 FNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHI 6687
YK+V+G LP T TQ R+ + F+PRS +E DFL ++ + F+ERY + +HI
Sbjct 6155 LYVYKRVNGAFVTLPNTINTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHI 6213
Query 6688 VYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTV-KNYFITDAQTGSSKCVCSV 6746
+YG+ QLGGLH +IG+ + + + + DS V +NYF+ + GS K VC+V
Sbjct 6214 LYGEVDKPQLGGLHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVL-SDNGSYKQVCTV 6272
Query 6747 IDLLLDDFV----EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQA 6802
+DLLLDDF+ I+K + SKVV V+IDY I+FM W +DG ++T YP+LQS A
Sbjct 6273 VDLLLDDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQS--A 6329
Query 6803 WQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYN 6862
W G MP LYK+Q ++E C++ NYG TLP GI+MNVAKYTQLCQYL T+ VP+N
Sbjct 6330 WTCGYNMPELYKVQNCVMEPCNIPNYGVGITLPSGILMNVAKYTQLCQYLLKTTICVPHN 6389
Query 6863 MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW 6922
MRV+HFGAGSDKGVAPG+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC +T +K+
Sbjct 6390 MRVMHFGAGSDKGVAPGSTVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYNTEHKF 6449
Query 6923 DLIISDMY---DPKTKNV-TKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADL 6978
DL+ISDMY D K K+ N+ + F Y+ F++ LALGGS A+K+TE SW+ L
Sbjct 6450 DLVISDMYTDNDSKRKHEGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSWHEVL 6509
Query 6979 YKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPRE-QIDGYVMHANYIFWRNTNPIQL 7037
Y + AWWT F T VNASSSEAFLIG NYLG + ++ G +HANYIFWRN N +Q
Sbjct 6510 YDIAQDCAWWTMFCTAVNASSSEAFLIGVNYLGASEKVKVSGKTLHANYIFWRNCNYLQT 6569
Query 7038 SSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLV 7094
S+YS+FD++KF L+L+ T V++LK Q D++ +L+ G+L++R+ +SD V
Sbjct 6570 SAYSIFDVAKFDLRLKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 6626
Score = 68.2 bits (165), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 57/243 (23%), Positives = 107/243 (44%), Gaps = 15/243 (6%)
Query 1570 VFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRV 1629
++ T D + + V+ + GQ FG Y V + + + YV D ++
Sbjct 1180 IYLTEDGVKYRSIVLKPGDSLGQ-FGQVYAKNKIV--FTADDVEDKEILYVPTTDKSI-- 1234
Query 1630 EAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELK 1689
EYY ++ Y+ L +KW + ++W D NC++++A++ LQ +++
Sbjct 1235 --LEYYGLDAQKYV-IYLQTL--AQKWNVQYRDNFLILEWRDGNCWISSAIVLLQAAKIR 1289
Query 1690 FNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLN 1749
F L +A+ + G+ +F A A C VG+ D ++ L +H + D L
Sbjct 1290 FK-GFLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFSDANWLLANLAEHFDADYTNAFLK 1348
Query 1750 --VVCKTCGQQQTTLKGVEA-VMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVM 1806
V C CG + L+G+EA + + + FK TCG T +++ P+++
Sbjct 1349 KRVSC-NCGIKSYELRGLEACIQPVRATNLLHFKTQYSNCPTCGANNTDEVIEASLPYLL 1407
Query 1807 MSA 1809
+ A
Sbjct 1408 LFA 1410
Score = 53.9 bits (128), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 53/192 (28%), Positives = 87/192 (45%), Gaps = 20/192 (10%)
Query 985 QQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV---QTIEVNSFSGYLKLTDNVYIK 1041
++ V Q+DG++ Q + I V+PQ E + T E F Y ++ +
Sbjct 971 EEVVSQKDGAQIKQ----EPIQVVKPQREKKAKKFKVKPATCEKPKFLEYKTCVGDLTVV 1026
Query 1042 NADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGG 1101
A ++E K+ +VNAAN ++ HG GVA A+ +DY+ +GP +
Sbjct 1027 IAKALDEFKEF---CIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ--- 1080
Query 1102 SCVLSGHNLAKHCL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGADP 1158
V C+ +VVGP + L +AY+N V+ + P+LS GIFG D
Sbjct 1081 RLVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGVD- 1139
Query 1159 IHSLRVCVDTVR 1170
++ +D +R
Sbjct 1140 ---FKMSIDAMR 1148
>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631
Score = 4152 bits (10769), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2260/4997 (45%), Positives = 3074/4997 (62%), Gaps = 258/4997 (5%)
Query 2229 IIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPC 2288
+I+WF+ S ++++ + + L S C Y + +S +V YC G C
Sbjct 1759 LIVWFIYTS---NPVVFTGIRV---LDFLFEGSLCGPYNDYGKDSFDVL--RYCAGDFTC 1810
Query 2289 SVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAI 2346
VCL DSL Y +++ A G+ W Y++F F V G I
Sbjct 1811 RVCLHDRDSLHLYKHAYSVEQIYKD-----AASGINFNWNWLYLVFLILFVKPVAGFVII 1865
Query 2347 MQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVV 2401
Y + + +S ++ + + + + + F + +Y W Y VH +
Sbjct 1866 -----CYCVKYLVLSSTVLQTGVGFLDWF-VKTVFTHFNFMGAGFYFWLFYKIYVQVHHI 1919
Query 2402 DGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAG 2461
C TC +C + R+ R E + +V G ++ +VY N G FCK HNW C NCD +
Sbjct 1920 LYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQ 1979
Query 2462 STFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKA-GQKTYERHSLSH 2520
+TF+S EVA +LS + KR + PT + ++V V + ++L + A K ++
Sbjct 1980 NTFMSPEVAGELSEKLKRHVKPTAYAYHVVYEACVVDDFVNLKYKAAIPGKDNASSAVKC 2039
Query 2521 FVNLDNLR-ANNTKGSLPINVIVFDGKSKCEESSA------KSASVYYSQLMCQPILLLD 2573
F D L+ A K +L I DG C SA K+A+VYY+Q +C+PIL+LD
Sbjct 2040 FSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSAHALEEAKNAAVYYAQYLCKPILILD 2099
Query 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
QAL + P+ K +++ + L+ +S+D +
Sbjct 2100 QAL---------------------YEQLIVEPVSK--SVIDKVCSILSNIISVDTAALNY 2136
Query 2634 ISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYN-KVENMTPRDLGACI 2692
+ + + S + ++ V+ H ++E TGD N + +Y + +TPRD G I
Sbjct 2137 KAGTLRDALLSITKDEEAVDMAIFCHNHEVEYTGDGFTNVIPSYGMDTDKLTPRDRGFLI 2196
Query 2693 DCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVN 2752
+ A N +V + + +W D + LS+ K + SA K+ F +T + +QV++
Sbjct 2197 NADASIANLRVKNAPPV--VWKFSDLIKLSDSCLKYLISATVKSGGRFFITKSGAKQVIS 2254
Query 2753 VVTTKIAL--KGGKIVNN---WLKQLIKVTLVF--LFVA---AIFYLITPVHVMSKHTDF 2802
T K+ + K G ++NN W K VF LF A +Y+ + D
Sbjct 2255 CHTQKLLVEKKAGGVINNTFKWFMSCFKWLFVFYILFTACCLGYYYMEMNKSFVHPMYDV 2314
Query 2803 SS--EIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITR 2860
+S + G+K ID GV R+I S D CF+NK +FD ++ G SY N+K CP++ VI
Sbjct 2315 NSTLHVEGFKVIDKGVIREIVSEDNCFSNKFVNFDAFW---GKSYENNKNCPIVTVVIDG 2371
Query 2861 EVGFVVPGLPGTILRTTNG-DFLH---------FLPRVFSA--VGNICYTPSKLIEYTDF 2908
+ G V G+PG + +G F+H ++P F+ VG YT +I F
Sbjct 2372 D-GTVAVGVPGFVSWVMDGVMFVHMTQTDRRPWYIPTWFNREIVG---YTQDSIITEGSF 2427
Query 2909 ATSACVLAAECTIFKDASGKPVPYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNT 2967
TS + +A C ++ AS P YC++ N G++ + S+ P Y +G + P
Sbjct 2428 YTSIALFSARC-LYLTASNTPQLYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQ 2486
Query 2968 YLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLL 3027
L V DS YCR CE ++ G CVS +WVL ND Y S PGVFCG L+
Sbjct 2487 ILHTPYIVKFVSDS-YCRGSVCEYTKPGYCVSLDSQWVLFNDEYISKPGVFCGSTVRELM 2545
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
NM + + +I + ++ +V+ + ++F+ F Y+ +V L++++
Sbjct 2546 FNMVSTFFTGVNP-NIYIQLATMFLILVVIVLIFAMVIKFQGVFKAYATIVFTIMLVWVI 2604
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWIT---IAY 3144
+ VLC+ S L + V+Y Y + + + + + H + F +VP W+ + +
Sbjct 2605 NAFVLCVHSYNSVLAVILLVLYCYASMVTSRNTAIIMHCWLVFTFGLIVPTWLACCYLGF 2664
Query 3145 IICISTKHFYWFFSNYLKRRVVFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQ 3203
I+ + T +W + R +++G F ++ AA TF++ ++KL +++ +
Sbjct 2665 ILYMYTPLVFWCYGTTKNTRKLYDGNEFVGNYDLAAKSTFVIRGTEFVKLTNEIG---DK 2721
Query 3204 YNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQ 3263
+ YL+ Y + KY+SG Y +A LA AL+ + NSG +V+Y PP+ SI + LQ
Sbjct 2722 FEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYALDQYRNSGVEVVYTPPRYSIGVSRLQ 2781
Query 3264 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 3323
+GF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ + D+L
Sbjct 2782 AGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVL---GKFSGDQWGDVLNL 2838
Query 3324 KSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 3382
+NH F V N V L V+ ++ VL L+ AN +TPKYKFV+ G +F++ Y
Sbjct 2839 ANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYG 2898
Query 3383 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3442
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G
Sbjct 2899 GTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMG 2958
Query 3443 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVIN-------GDRWFLNRFTTTLNDFNL 3495
FYG +VD + AQ D +T N++AWLYAA+I+ +W L T ++ D+N
Sbjct 2959 EFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKW-LESTTVSIEDYNR 3017
Query 3496 VAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRT--ILGSALLEDE 3553
A + P + + LSA TG+ D+C L+ ++ + ILG EDE
Sbjct 3018 WASDNGFTPFSTSTA--ITKLSAITGV---DVCKLLRTIMVKSAQWGSDPILGQYNFEDE 3072
Query 3554 FTPFDVVRQCSGVTFQSAVKRTIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENA 3610
TP V Q GV QS+ R + W +L L L +V T L F+++
Sbjct 3073 LTPESVFNQVGGVRLQSSFVRKAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVHAAV 3131
Query 3611 FLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRI 3663
L A+ I+ + VKH A++ FLLP+L TV A +Y + + V+ +
Sbjct 3132 ILLMAVLFISFT------VKHVMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFL 3185
Query 3664 MTWLDMV--DTSL----------SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWT 3710
W D V DT + + FK ++ C M + LL+L + ++T
Sbjct 3186 SQWYDPVVFDTMVPWMLLPLVLYTAFKCVQGCYMNSFNTSLLMLYQFMKL----GFVIYT 3241
Query 3711 LMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVE----YC 3766
N LT + GN W L + + L IVF C + YC
Sbjct 3242 SSNTLTAYTE---GN--------WELFFELVHTIVLANVSSNSLIGLIVFKCAKWMLYYC 3290
Query 3767 PIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQ 3826
+ L +M+ +G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM
Sbjct 3291 NATYFNNYVLMAVMVN--GIGWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLH 3348
Query 3827 GLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSK 3886
+ PPK + F NI + G+GG + +ATVQSK+SDVKCT+VVL+ +L +L VE++SK
Sbjct 3349 KVNPPKTVWEVFTTNILIQGIGGDRVLPIATVQSKLSDVKCTTVVLMQLLTKLNVEANSK 3408
Query 3887 LWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIAS 3946
+ A V+LHN IL + D E + ++ +L L + +D+ + C+++L LQ++
Sbjct 3409 MHAYLVELHNKILASDDVGECMDNLLGMLITLFCIDSTIDLGEYCDDILKRSTVLQSVTQ 3468
Query 3947 EFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE 4002
EFS +PSYA + A+ YE+ +A+ G ++ L +K+ N+AKS FDRD A+Q+KL+
Sbjct 3469 EFSHIPSYAEYERAKSIYEKVLADSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLD 3528
Query 4003 KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII 4062
MA++AMT MYK+AR D+RAK+ S++ +LF+ML+K+D++ LN + + A G VPL +
Sbjct 3529 SMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQANSGVVPLATV 3588
Query 4063 PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD----- 4117
P+ + KL +VIPD T+ +G TY++ +W I V DAD + +
Sbjct 3589 PIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDCVTDADGTELHPTSTGSGLTYCI 3648
Query 4118 NSPNLAWPLIVTALRANSA---VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNT 4174
+ N+AWPL V R V LQNNEL P ++ +C AG Q C+ ++ YY +
Sbjct 3649 SGDNIAWPLKVNLTRNGHNKVDVALQNNELMPHGVKTKACVAGVDQAHCSVESK-CYYTS 3707
Query 4175 TKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGL 4234
G V A+ S +LK A F G IY +L+PPC+F +V YLYFIK
Sbjct 3708 ISGSSVVAAITSSNPNLKVASFLNEAGN-QIYVDLDPPCKFGMKVGDKVEVVYLYFIKNT 3766
Query 4235 NNLNRGMVLGSLAATVRLQA-GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITN 4293
++ RGMVLG+++ V LQ+ G+ TE +LS C+FAVD A Y Y+A+G QP+ N
Sbjct 3767 RSIVRGMVLGAISNVVVLQSKGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGN 3826
Query 4294 CVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKY 4349
CVKML H G+G AIT P DQ+S+GGAS CLYCR HI HP N G C KG +
Sbjct 3827 CVKMLTVHNGSGFAITSKPSPTPDQDSYGGASVCLYCRAHIAHPGGAGNLDGRCQFKGSF 3886
Query 4350 VQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREP-------MLQSADAQSFLNR 4402
VQIPTT DPVGF L+N VCTVC W GYGC CD LR+P + S +++LNR
Sbjct 3887 VQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGCQCDSLRQPKPSVQSVAVASGFDKNYLNR 3945
Query 4403 VCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQE--KDEDDNL--I 4458
V G S ARL P G DVV RAFD+ N + AG + LK NC RFQE ED NL
Sbjct 3946 VRGSSEARLIPLANGCDPDVVKRAFDVCNKESAGMFQNLKRNCARFQEVRDTEDGNLEYC 4005
Query 4459 DSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMAD 4518
DSYFVVK+ T SNY+HE+ Y LK A HDFF F + + +ISRQRLTKYTM D
Sbjct 4006 DSYFVVKQTTPSNYEHEKACYEDLKS-EVTADHDFFVFNKN---IYNISRQRLTKYTMMD 4061
Query 4519 LVYALRHFDEGNCDTLKEILVTYNCCDD---DYFNK-KDWYDFVENPDILRVYANLGERV 4574
YALRHFD +C+ LKEILVTY C +D +F + KDWYD +ENP + A +G V
Sbjct 4062 FCYALRHFDPKDCEVLKEILVTYGCIEDYHPKWFEENKDWYDPIENPKYYAMLAKMGPIV 4121
Query 4575 RQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLM 4634
R+ALL ++F + M G VGV+TLDNQDLNG +YDFGDF +T PG+GVPV D+YYS +M
Sbjct 4122 RRALLNAIEFGNLMVEKGYVGVITLDNQDLNGKFYDFGDFQKTAPGAGVPVFDTYYSYMM 4181
Query 4635 PILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCL 4694
PI+ +T AL E + + D+ K Y +DLLKYD+TEE+ LF +YFKYWDQ YHPNC +C
Sbjct 4182 PIIAMTDALAPERYFEYDVHKGYKSYDLLKYDYTEEKQDLFQKYFKYWDQEYHPNCRDCS 4241
Query 4695 DDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLH 4754
DDRC++HCANFN+LFST+ P TSFG L RK+FVDGVPF+ + GYH +ELGV+ NQD +
Sbjct 4242 DDRCLIHCANFNILFSTLVPQTSFGNLCRKVFVDGVPFIATCGYHSKELGVIMNQDNTMS 4301
Query 4755 SSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDF 4814
S++ +L+ + DPA+ + N L+D RT+CFSV AL + + QTVKPG+FNKDFYDF
Sbjct 4302 FSKMGLSQLMQFVGDPALLVGTSNKLVDLRTSCFSVCALASGITHQTVKPGHFNKDFYDF 4361
Query 4815 AVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDC 4874
A G FKEGSS+ LKHFF+ Q GNAAI+DYDYYRYN PTM DIRQLLF +EV KYF+C
Sbjct 4362 AEKAGMFKEGSSIPLKHFFYPQTGNAAINDYDYYRYNRPTMFDIRQLLFCLEVTSKYFEC 4421
Query 4875 YDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQM 4934
Y+GGCI A+QV+VNNLDKSAG+PFNK+GKARLYY+ MS E+QD LF TK+NV+PTITQM
Sbjct 4422 YEGGCIPASQVVVNNLDKSAGYPFNKFGKARLYYE-MSLEEQDQLFESTKKNVLPTITQM 4480
Query 4935 NLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNML 4994
NLKYAISAKNRARTVAGVSI STMTNRQFHQK+LKSI TR A VVIGT+KFYGGW NML
Sbjct 4481 NLKYAISAKNRARTVAGVSILSTMTNRQFHQKILKSIVNTRNAPVVIGTTKFYGGWDNML 4540
Query 4995 KTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQV 5054
+ + VE+P LMGWDYPKCDRAMPN+LRI ASLVLARKHT CC+ S R YRL NECAQV
Sbjct 4541 RNLIQGVEDPILMGWDYPKCDRAMPNLLRIAASLVLARKHTNCCTWSERVYRLYNECAQV 4600
Query 5055 LSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRN 5114
LSE V+ G +YVKPGGTSSGDATTAYANSVFNI QA +ANV LLS I +++
Sbjct 4601 LSETVLATGGIYVKPGGTSSGDATTAYANSVFNIIQATSANVARLLSVITRDIVYDDIKS 4660
Query 5115 LQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNF 5174
LQ+ LY+ +YR + D FV +FY+YL K+FS+MILSDD VVC+N+T A QGLVA I F
Sbjct 4661 LQYELYQQVYRRVNFDPAFVEKFYSYLCKNFSLMILSDDGVVCYNNTLAKQGLVADISGF 4720
Query 5175 KSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGC 5234
+ VLYYQNNVFM+++KCW E DL KGPHEFCSQHTMLV+ + YLPYPDPSRIL A
Sbjct 4721 REVLYYQNNVFMADSKCWVEPDLEKGPHEFCSQHTMLVEVDGEPRYLPYPDPSRILCACV 4780
Query 5235 FVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDM 5294
FVDD+ KT+ ++ER+++LAIDAYPL H N+EY VF + L YIRKL+ EL+ +ML
Sbjct 4781 FVDDLDKTESVAVMERYIALAIDAYPLVHHENEEYKKVFFVLLSYIRKLYQELSQNMLMD 4840
Query 5295 YSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCC 5354
YS ++ D S++WE EFYE MY T LQ+ G CV+CNSQT LRCG CIR+PFLCCKCC
Sbjct 4841 YSFVMDIDKGSKFWEQEFYENMYRAPTTLQSCGVCVVCNSQTILRCGNCIRKPFLCCKCC 4900
Query 5355 YDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVF 5414
YDHV+ T HK VLS+NPY+C+ PGC DVT+LYLGGMSY+C +HKP +S PL +NG VF
Sbjct 4901 YDHVMHTDHKNVLSINPYICSQPGCGEADVTKLYLGGMSYFCGNHKPKLSIPLVSNGTVF 4960
Query 5415 GLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYG 5474
G+Y+ C GS+NV DFN +AT +W+ YILAN C + L+ FAAET+KATEE K +
Sbjct 4961 GIYRANCAGSENVDDFNQLATTNWSTVEPYILANRCVDSLRRFAAETVKATEELHKQQFA 5020
Query 5475 IATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVV 5534
A VREVLSDREL LSWE GK RPPLNRNYVFTG+ T+ SKVQ+G++TFEKG+ D V
Sbjct 5021 SAEVREVLSDRELILSWEPGKTRPPLNRNYVFTGFHFTRTSKVQLGDFTFEKGEGKDVVY 5080
Query 5535 YRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQ 5594
YR T+T KL+VGD FVLTSH V+ L APTL PQ+ + R L P + + F +N+ Y
Sbjct 5081 YRATSTAKLSVGDIFVLTSHNVVSLIAPTLCPQQTFSRFVNLRPNVMVPACFVNNIPLYH 5140
Query 5595 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5654
VG QK +T+QGPPG+GKSHFAIGLA Y+ +AR+V+TACSHAAVDALCEKA K+L +D C
Sbjct 5141 LVGKQKRTTVQGPPGSGKSHFAIGLAAYFSNARVVFTACSHAAVDALCEKAFKFLKVDDC 5200
Query 5655 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNAR 5714
+RI+P R ++CF KFK N T ++Y+F T+NALPE + DI++ DE+SM TNY+LS +N +
Sbjct 5201 TRIVPQRTTIDCFSKFKANDTGKKYIFSTINALPEVSCDILLVDEVSMLTNYELSFINGK 5260
Query 5715 LRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVD 5774
+ ++ VY+GDPAQLPAPRTLL G+L P+ +N V LM + PD+FL C RCP EIVD
Sbjct 5261 INYQYVVYVGDPAQLPAPRTLLN-GSLSPKDYNVVTNLMVCVKPDIFLAKCYRCPKEIVD 5319
Query 5775 TVSALVYDNKLKAHKDKSAQCFKMFYKGV---ITHDVSSAINRPQIGVVREFLTRNPAWR 5831
TVS LVYD K A+ +S QCFK+ + H+ SA N Q+ V++F+ RN WR
Sbjct 5320 TVSTLVYDGKFIANNPESRQCFKVIVNNGNSDVGHESGSAYNITQLEFVKDFVCRNKEWR 5379
Query 5832 KAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITR 5891
+A FISPYN+ N A ++LGL QTVDSSQGSEYDYVIF T ++ H+ N+NRFNVA+TR
Sbjct 5380 EATFISPYNAMNQRAYRMLGLNVQTVDSSQGSEYDYVIFCVTADSQHALNINRFNVALTR 5439
Query 5892 AKVGILCIMSDRD-LYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPT 5950
AK GIL +M RD LY L+F L+ +VA+LQ TGLFK C+K +G+HP A T
Sbjct 5440 AKRGILVVMRQRDELYSALKFIELD----SVASLQG---TGLFKICNKEFSGVHPAYAVT 5492
Query 5951 HLSVDTKFKTEGLCVDIPGIP--KDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHV 6008
++ +K + + ++TY+ LIS++GFKM+ V G NMFITR+EAIR+V
Sbjct 5493 TKALAATYKVNDELAALVNVEAGSEITYKHLISLLGFKMSVNVEGCHNMFITRDEAIRNV 5552
Query 6009 RAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPG 6068
R W+GFDVE HA +GTNLP Q+GFSTG + V P G VDT +F V++K PPG
Sbjct 5553 RGWVGFDVEATHACGTNIGTNLPFQVGFSTGADFVVTPEGLVDTSIGNNFEPVNSKAPPG 5612
Query 6069 DQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGP 6128
+QF HL L PW+VVR +IVQML+D L N+SD VVFV W HG ELT+++YFVKIG
Sbjct 5613 EQFNHLRALFKSAKPWHVVRPRIVQMLADNLCNVSDCVVFVTWCHGLELTTLRYFVKIGK 5672
Query 6129 ERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQV 6188
++ C C RAT F++ + YACW H +GFD+VYNP ++D+QQWG++GNLQ NHDL+C V
Sbjct 5673 DQVCS-CGSRATTFNSHTQAYACWKHCLGFDFVYNPLLVDIQQWGYSGNLQFNHDLHCNV 5731
Query 6189 HGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLA 6248
HG+AHVAS DAIMTRCLA++ F + V+W + YP I +E ++N++CR +Q M + A + A
Sbjct 5732 HGHAHVASADAIMTRCLAINNAFCQDVNWDLTYPHIANEDEVNSSCRYLQRMYLNACVDA 5791
Query 6249 DKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCL 6308
K V++DIGNPK IKCV + D+ ++FYD P + E Y Y H DKF DG+C+
Sbjct 5792 LKVNVVYDIGNPKGIKCVRRGDLNFRFYDKNPIVPNVKQFE---YDYNQHKDKFADGLCM 5848
Query 6309 FWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLP 6368
FWNCNVD YP NS+VCR+DTR LS NLPGC+GGSLYVNKHAFHTP FD+++F NLK +P
Sbjct 5849 FWNCNVDCYPDNSLVCRYDTRNLSVFNLPGCNGGSLYVNKHAFHTPKFDRTSFRNLKAMP 5908
Query 6369 FFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMIS 6428
FF+Y SPCE+ V+ D V L + CIT+CN+GGAVC+ HA Y ++ +YN ++
Sbjct 5909 FFFYDSSPCETIQLDGVAQ-DLVSLATKDCITKCNIGGAVCKKHAQMYADFVTSYNAAVT 5967
Query 6429 AGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVD 6488
AGF+ WV F+ YNLW +F+ LQS++N+A+N+ GH+D GE+P + + V+
Sbjct 5968 AGFTFWVTNNFNPYNLWKSFSALQSIDNIAYNMYKGGHYDAIAGEMPTIVTGDKVFVIDQ 6027
Query 6489 GVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHI 6548
GV+ +F N+T LP +VAFEL+AKRNI+ +P +IL LGVD+ VIWDY P +
Sbjct 6028 GVEKAVFFNQTILPTSVAFELYAKRNIRTLPNNRILKGLGVDVTNGFVIWDYTNQTPLYR 6087
Query 6549 STIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVG 6608
+T+ VC+ TDI L V +D R G F A N VL++ K
Sbjct 6088 NTVKVCAYTDIEPN-------GLIVLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEI 6139
Query 6609 PKQASL-NGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLE 6667
P + NG+ L A YK+V+G LP T TQ R+ + F+PRS +E DFL+
Sbjct 6140 PSNLLVQNGIPLKDGA---NLYVYKRVNGAFVTLPNTLNTQGRSYETFEPRSDVERDFLD 6196
Query 6668 LAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTV 6727
++ + F+E+Y E +HI+YG+ QLGGLH +IG+ + + + + DS V
Sbjct 6197 MSEESFVEKYGKE-LGLQHILYGEVDKPQLGGLHTVIGMCRLLRANKLNAKSVTNSDSDV 6255
Query 6728 -KNYFITDAQTGSSKCVCSVIDLLLDDFV----EIIKSQDLSVVSKVVKVTIDYTEISFM 6782
+NYF+ A GS K VC+V+DLLLDDF+ I+K + SKVV V+IDY I+FM
Sbjct 6256 MQNYFVL-ADNGSYKQVCTVVDLLLDDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFM 6313
Query 6783 LWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNV 6842
W +DG ++T YP+LQS AW G MP LYK+Q ++E C++ NYG LP GIMMNV
Sbjct 6314 AWFEDGIIKTCYPQLQS--AWTCGYNMPELYKVQNCVMEPCNIPNYGVGIALPSGIMMNV 6371
Query 6843 AKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFV 6902
AKYTQLCQYL+ T+ VP+NMRV+HFGAGSDKGVAPG+ VL+QWLP GTLLVD+D+ D+V
Sbjct 6372 AKYTQLCQYLSKTTMCVPHNMRVMHFGAGSDKGVAPGSTVLKQWLPEGTLLVDNDIVDYV 6431
Query 6903 SDADSTLIGDCATVHTANKWDLIISDMY---DPKTKNV-TKENDSKEGFFTYICGFIQQK 6958
SDA +++ DC T +K+DL+ISDMY D K K+ N+ + F Y+ F++
Sbjct 6432 SDAHVSVLSDCNKYKTEHKFDLVISDMYTDNDSKRKHEGVIANNGNDDVFIYLSSFLRNN 6491
Query 6959 LALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPRE-QI 7017
LALGGS A+K+TE SW+ LY + AWWT F T VNASSSEAFL+G NYLG + ++
Sbjct 6492 LALGGSFAVKVTETSWHEVLYDIAQDCAWWTMFCTAVNASSSEAFLVGVNYLGASEKVKV 6551
Query 7018 DGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGR 7077
G +HANYIFWRN N +Q S+YS+FD++KF L+L+ T V++LK Q D++ +L+ G+
Sbjct 6552 SGKTLHANYIFWRNCNYLQTSAYSIFDVAKFDLRLKATPVVNLKTEQKTDLVFNLIKCGK 6611
Query 7078 LIIRENNRVVISSDVLV 7094
L++R+ +SD V
Sbjct 6612 LLVRDVGNTSFTSDSFV 6628
Score = 72.4 bits (176), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 57/242 (24%), Positives = 108/242 (45%), Gaps = 13/242 (5%)
Query 1570 VFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRV 1629
++ T D + + V+ + GQ FG + A + + E K +P D +
Sbjct 1182 IYLTEDGVKYRSVVLKPGDSLGQ-FGQVF---ARNKVVFSADDVEDKEILFIPTTDKTIL 1237
Query 1630 EAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELK 1689
E Y+ D Y+ L +KW + ++W D NC++++A++ LQ +++
Sbjct 1238 E----YYGLDAQKYVTYLQTL--AQKWDVQYRDNFVILEWRDGNCWISSAIVLLQAAKIR 1291
Query 1690 FNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVL- 1748
F L +A+ + G+ +F A A CN VG+ D ++ L +H + D +L
Sbjct 1292 FK-GFLAEAWAKLLGGDPTDFVAWCYASCNAKVGDFSDANWLLANLAEHFDADYTNALLK 1350
Query 1749 NVVCKTCGQQQTTLKGVEA-VMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
V CG + L+G+EA + + + FK TCG +T +++ P++++
Sbjct 1351 KCVSCNCGVKSYELRGLEACIQPVRAPNLLHFKTQYSNCPTCGASSTDEVIEASLPYLLL 1410
Query 1808 SA 1809
A
Sbjct 1411 FA 1412
Score = 51.6 bits (122), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 50/180 (28%), Positives = 80/180 (44%), Gaps = 28/180 (16%)
Query 1009 QPQLEMELTPVVQ---------------TIEVNSFSGYLKLTDNVYIKNADIVEEAKKVK 1053
+PQ+E E T VV+ T E F Y ++ + A ++E K+
Sbjct 981 EPQVEQEPTLVVKAQREKKAKKFKVKPATCEKPKFLEYKTCVGDLAVVIAKALDEFKEF- 1039
Query 1054 PTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKH 1113
+VNAAN ++ HGGGVA A+ DY+ +GP + V
Sbjct 1040 --CIVNAANEHMSHGGGVAKAIADFCGPDFVEYCADYVKKHGPQQ---KLVTPSFVKGIQ 1094
Query 1114 CL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGADPIHSLRVCVDTVR 1170
C+ +VVGP + L +AY++ V+ + P+LS+GIFG D ++ +D +R
Sbjct 1095 CVNNVVGPRHGDSNLREKLVAAYKSVLVGGVVNYVVPVLSSGIFGVD----FKISIDAMR 1150
>sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus
HKU9 OX=694006 GN=1a PE=3 SV=1
Length=4248
Score = 2550 bits (6610), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1605/4497 (36%), Positives = 2393/4497 (53%), Gaps = 405/4497 (9%)
Query 28 VRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV--LPQLEQPYVFIKRSDARTAPHG-HV 84
V G+ +EE L A+Q L+ LV V + P + V I S G
Sbjct 29 VTGWDIPIEEALEYAKQQLRTPEPQLVFVPYYLSHAPGISGDRVVITDSIWYATNFGWQP 88
Query 85 MVELVAELEGIQYGRSGETLGVLVPH------VGEIPVAYRKVLLRKNGNKGAGGHSYGA 138
+ EL + +G++YGR G T GVL+P +G+I + RK G G +S
Sbjct 89 IRELAMDKDGVRYGRGG-THGVLLPMQDPSFIMGDIDIQIRKY--------GIGANSPPD 139
Query 139 DLKSFDLGDELGTD--PYEDFQENW-NTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
L +D + G D PY DF +N TK + ++ G DNN G
Sbjct 140 VLPLWDGFSDPGPDVGPYLDFPDNCCPTKPKAKRGGDVYLSDQYG-----FDNN-----G 189
Query 196 YPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPF 255
+E + LL K+ TL + L + G Y R+E Y+L +
Sbjct 190 ILVEPVMKLLGVI-KSDFTLEQLLAAL----GKY--------------RTEDGYDLPDGY 230
Query 256 ---EIKLAKK------------FDTFNGECPNFVFPLN--SIIKTIQPRVEKKKLDGFMG 298
IK+ +K P + +P + S+++ +P
Sbjct 231 VKVAIKVGRKAVPVLKQSIFTVVGVTEQLVPGYYYPFSTSSVVEHTKPTRGGPVGKTVEA 290
Query 299 RIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTE-NLTKEGATTC 357
+ S+Y N N +KC +C W + CG E LT ++C
Sbjct 291 VMLSLY---GTNNYNPATPVARLKCSYCDYYGWTPLKDIGTVNCLCGAEFQLT----SSC 343
Query 358 GYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRT-IAFGGCVFSYVGC 416
V+K P C + G++ I G RT ++FGG ++S +G
Sbjct 344 VDAESAGVIK---PGC----------VMLLDKSPGMRLI--PGNRTYVSFGGAIWSPIGK 388
Query 417 HNKCAYWVPRASANIGCNHTGVVGEG-SEGLNDNLLEILQKEKVNINIVGDFKLNEEIAI 475
N WVPRA + + H+G VG G + +N L+E L + I + D N A
Sbjct 389 VNGVTVWVPRAYSIVAGEHSGAVGSGDTVAINKELVEYLIE---GIRVDADTLDNPTCAT 445
Query 476 ILASFSASTSA----FVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILS 531
+A+ T A VE+++GL C K+ G E +
Sbjct 446 FIANLDCDTKAPVVHTVESLQGL-----------CLANKIMLGDKP---LPTDEFHPFIV 491
Query 532 PLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLA 591
L A+ + A ++ SRT E ++ VR ++ +Q+ ++ +
Sbjct 492 GL-AYHVQRACWYGALASRTFEAFRDFVRTEEER-------FAQFFGKVCAPI------- 536
Query 592 TNNLVVMAYITGGVVQLTSQWLTN------------IFGTVYEKLKPVLDWLEEKFKEGV 639
N V +AY TG V ++ + N + V + LKP+L+W+ +K +
Sbjct 537 -NGCVYLAYTTGRVTLFSAYQVLNTAIAKSKDAFGGVAAIVVDMLKPILEWVLKK----M 591
Query 640 EFLRDGW----EIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIII 695
+ W E + + +V G+ + + L+ ++ S+
Sbjct 592 SIAKGAWLPYAEGLLALFKAQFTVVKGKFQFLRASLNSKCHSLCDLLTTIMSKLLTSVKW 651
Query 696 GGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLM-PLKAPKEIIFLEGETLPTEVLTE 754
G K+ AL G + KG+ + + GLL+ P + E+ L+G+ LT+
Sbjct 652 AGCKVDALYTGTYYYFSRKGVLTEVQLCAKRLGLLLTPKQQKMEVEVLDGDFDAPVTLTD 711
Query 755 EVVLKTGDLQPLEQPTSEAVEAPLV-GTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTF 813
L+ + + + A + LV GT V + + + +D Y + V F
Sbjct 712 ---LELEECTGVLEEVFGASDVKLVKGTLVSLASKLFVRTEDGFLY-RYVKSGGVLGKAF 767
Query 814 TLKGGAPTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFAC 873
L+GG +KVTFGD+ V + +VN ++++ E +D +L++ + + VE GT++ + AC
Sbjct 768 RLRGGGVSKVTFGDEEVHTIPNTVTVNFSYDVCEGLDAILDKVMAPFQVEEGTKLEDLAC 827
Query 874 VVADAVIKTLQPV----SELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYP--P 927
VV AV + L + L P I+L+++ + +++ + E L MY S P
Sbjct 828 VVQKAVYERLSDLFSDCPAELRP--INLEDFLTSECFVYSKDYEKILMPEMYFSLEDAVP 885
Query 928 DEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQT 987
+DE D E+ ++ + ++ WL D
Sbjct 886 VDDEMVDDIED-----------------------------TVEQASDSDDQWLGD----- 911
Query 988 VGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVE 1047
+G+ED TI +V M TP GY K+ ++VYIK ADIV+
Sbjct 912 ----EGAEDCD----NTIQDVDVATSMT-TP----------CGYTKIAEHVYIKCADIVQ 952
Query 1048 EAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSG 1107
EA+ V+VNAANV L HGGGVAGALN+ATNNAMQ ES +YI NG L+ GG +LS
Sbjct 953 EARNYSYAVLVNAANVNLHHGGGVAGALNRATNNAMQKESSEYIKANGSLQPGGHVLLSS 1012
Query 1108 HNLAKH-CLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCV 1166
H LA H LHVVGP+ G+D+ LL + Y + + +L PL+SAGIFG SL V
Sbjct 1013 HGLASHGILHVVGPDKRLGQDLALLDAVYAAYTGFDSVLTPLVSAGIFGFTVEESLCSLV 1072
Query 1167 DTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRK 1226
V Y+ V+D+ LY++ +++ ++ + Q + I E E + S+ +
Sbjct 1073 KNVACTTYVVVYDRQLYERALATSFDVPGPQSSVQHVPAIDWAEA----VEVQESIVDQV 1128
Query 1227 QDDK--KIKACVEEVTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDITFLKKDAP 1284
+ + + L ET EN++ + PD +V+D++
Sbjct 1129 ETPSLGAVDTVDSNADSGLNETARSPENVVGSV-------PDD--VVADVE--------- 1170
Query 1285 YIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKVPTDNYITTYPGQGLNGYTVEEAKT 1344
V D+V++ V +KV D P + TVE+
Sbjct 1171 SCVRDLVRQVV----------------------KKVKRDK----RPPPIVPQQTVEQQPQ 1204
Query 1345 VLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQR 1404
+ +L ++S + M+ +E L+PV ++ A + ++R
Sbjct 1205 EISSPGDCNTVLVDVVS-----------MSFSAMVNFGKEKGLLIPVVIDYPAFLKVLKR 1253
Query 1405 KYKGIKIQEGVVDY-GARFYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAA 1463
+EG+ G FY Y+ + + LN L L+ +P G++ +G L +A
Sbjct 1254 ----FSPKEGLFSSNGYEFYGYSRDKPLHEVSKDLNSLGRPLIMIPFGFIVNGQTLAVSA 1309
Query 1464 RYMRSLKVPATVSVSSPDAVTAYNGYLT---SSSKTPEEHFIETISLAGSYKDWSYSGQS 1520
MR L VP TV V S +V Y Y S T + F+ I L G+ +DW +
Sbjct 1310 VSMRGLTVPHTVVVPSESSVPLYRAYFNGVFSGDTTAVQDFVVDILLNGA-RDWDVLQTT 1368
Query 1521 TQLGIE----FLKRGDKSVYYTSNPTTFHLDGEVI-TFDNLKTLLSLREVR------TIK 1569
+ + KRG+ + + + + + G+V+ F + + E + IK
Sbjct 1369 CTVDRKVYKTICKRGNTYLCF-DDTNLYAITGDVVLKFATVSKARAYLETKLCAPEPLIK 1427
Query 1570 VFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRV 1629
V TTVD IN T +V + +Y Q G + DG D + P + EG Y N + V
Sbjct 1428 VLTTVDGINYSTVLVSTAQSYRAQIGTVFCDGHDWSNKNPMPTDEGTHLYKQDNFSSAEV 1487
Query 1630 EAF-EYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIEL 1688
A EYY D + + R MS + W Y V+G + D+NCYL A+ LQ I++
Sbjct 1488 TAIREYYGVDDSNIIARAMSIRKTVQTWPYTVVDGRVLLAQRDSNCYLNVAISLLQDIDV 1547
Query 1689 KFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVL 1748
F+ P + AY + G +++A T G D +S + H + + +RV+
Sbjct 1548 SFSTPWVCRAYDALKGGNPLPMAEVLIALGKATPGVSDDAHMVLSAVLNHGTV-TARRVM 1606
Query 1749 NVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMS 1808
VC+ CG Q G +A + G++ + V + C CG+ A +Y+ +Q+SP+++MS
Sbjct 1607 QTVCEHCGVSQMVFTGTDACTFYGSVVLDDLYAPVSVVCQCGRPAIRYVSEQKSPWLLMS 1666
Query 1809 APPAQYELK-HGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
P Q L G + A + G GHY + + + D ++S+ K P TD+
Sbjct 1667 CTPTQVPLDTSGIWKTAIVFRGPVTAGHYMYAVNGTLISVYDANTRRRTSDLKLPATDIL 1726
Query 1868 YKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPNASFDN 1927
Y S+T+ K TY LDGV T IDP Y K+ + YFT PI++V P S+D
Sbjct 1727 YGPTSFTSDSKVETYYLDGVKRTTIDPDFSKYVKRGDYYFTTAPIEVVA-APKLVTSYDG 1785
Query 1928 FKF-VCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLL 1986
F C N + A+ N+ K +L +T +P++ GDVVAI + + G+ +
Sbjct 1786 FYLSSCQNPQLAESFNKAINATKTGPMKL-LTMYPNVAGDVVAISDDNVV-AHPYGSLHM 1843
Query 1987 HKPIVWHVNNATNKATYKPNTW-CIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLK 2045
KP+++ +PNTW + L ST V T N++DVL D
Sbjct 1844 GKPVLF---------VTRPNTWKKLVPLLSTVVVNTPNTYDVLAV------------DPL 1882
Query 2046 PVSEEVVENP-TIQKDVLECNVKTTEVVGDIILKPANNS-LKITEEVGHTDLMAAYVDN- 2102
PV+ E E P +++ + +K T V+ P N L +E TDL YV+
Sbjct 1883 PVNNETSEEPISVKAPIPLYGLKATMVLNGTTYVPGNKGHLLCLKEFTLTDLQTFYVEGV 1942
Query 2103 SSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT--NIVTRC 2160
+ K + LS+VLGL+ + VN + + YA L V+T+ +VTR
Sbjct 1943 QPFVLLKASHLSKVLGLRV--SDSSLHVNHLSKGVVYAYAATRLTTRVTTSLLGGLVTRS 2000
Query 2161 LNRV------------CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGK 2208
+ + C + F+ L ++ + +K S IA NT V
Sbjct 2001 VRKTADFVRSTNPGSKCVGLLCLFYQLFMRFWLLVKKP-PIVKVS--GIIAYNTGCGVTT 2057
Query 2209 FCLEASFNYLKSP----NFSKLINII-----IWFLL--LSVCLGSLIYSTAALGVLMSNL 2257
L NYL+S ++S+L+ ++ IWF+ L++C GV +S
Sbjct 2058 CVL----NYLRSRCGNISWSRLLKLLRYMLYIWFVWTCLTIC-----------GVWLSEP 2102
Query 2258 GMPSYCTGYRE--GYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFK 2315
PS T ++ G + + + +C++G+DSLD YP+L Q S
Sbjct 2103 YAPSLVTRFKYFLGIVMPCDYVLVNETGTGWLHHLCMAGMDSLD-YPALRMQQHRYGS-P 2160
Query 2316 WDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMA 2375
++ T ++ E F AY+L+T ++G+ A++ L Y + + NSWL+ + ++++
Sbjct 2161 YNYTYILMLLEAFFAYLLYTPALPIVGILAVLHLIVLYLPIP-LGNSWLVVFLYYIIRLV 2219
Query 2376 PISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFY 2435
P ++M+RMYI A + +K ++HV GCN+ C+MCYK+N A R+EC+T+VNGV+R FY
Sbjct 2220 PFTSMLRMYIVIAFLWLCYKGFLHVRYGCNNVACLMCYKKNVAKRIECSTVVNGVKRMFY 2279
Query 2436 VYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVT 2495
V ANGG FC HNWNCV+CDT+ STFI +VA DLS QFKRPI TD++ Y V SV
Sbjct 2280 VNANGGTHFCTKHNWNCVSCDTYTVDSTFICRQVALDLSAQFKRPIIHTDEAYYEVTSVE 2339
Query 2496 VKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLP-INVIVFDGKSKCEESSA 2554
V+NG ++ YF+ GQ++YER + F N+ L + KG+ P NV+VFD ++ EE++
Sbjct 2340 VRNGYVYCYFESDGQRSYERFPMDAFTNVSKLHYSELKGAAPAFNVLVFDATNRIEENAV 2399
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
K+A++YY+QL C+PILL+D+ +V VGD A +A MF+AY + +++ M+K+K L +
Sbjct 2400 KTAAIYYAQLACKPILLVDKRMVGVVGDDATIARAMFEAYAQNYLLKYSIAMDKVKHLYS 2459
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGFVD--SDVETKDVVECLKLSHQSDIEVTGDSCNN 2672
TA +++ +++++VL F+ + R D SDV+T D+V C++L HQ E T DS NN
Sbjct 2460 TALQQISSGMTVESVLKVFVGSTRAEAKDLESDVDTNDLVSCIRLCHQEGWEWTTDSWNN 2519
Query 2673 YMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSA 2732
+ TY K + ++ ++G + +A+++NA +AK + LIW DF+ LSE +R+Q++ A
Sbjct 2520 LVPTYIKQDTLSTLEVGQFMTANAKYVNANIAKGAAVNLIWRYADFIKLSESMRRQLKVA 2579
Query 2733 AKKNNLPFKLTCATTRQVVNVVTTKIALKGG-KIVNNWLKQLIKVTLVFLFVAAIFYLIT 2791
A+K L +T ++ + V + T + GG + + +W + LI V ++ + + ++ T
Sbjct 2580 ARKTGLNLLVTTSSLKADVPCMVTPFKIIGGHRRIVSWRRVLIHVFMLLVVLNPQWF--T 2637
Query 2792 PVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKAC 2851
P ++M ++ +K ID V RDI S D CFANK + F+ W+S R GSY N + C
Sbjct 2638 PWYIMRP---IEYNVVDFKVIDNAVIRDITSADQCFANKFSAFENWYSNRYGSYVNSRGC 2694
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRV---FSAVGNICYTPSKLIEYTDF 2908
P++ V++ VG +VPGLP LR LP V AVG++CYTP I Y F
Sbjct 2695 PMVVGVVSDIVGSLVPGLPARFLRVGT----TLLPLVNYGLGAVGSVCYTPHYAINYDVF 2750
Query 2909 ATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNT 2967
TSACVLAA CT+F ASG+ +PYC D +++ + Y+ L+P Y + S I+FP
Sbjct 2751 DTSACVLAATCTLFSSASGERMPYCADAALIQNASRYDMLKPHVMYPFYEHSGYIRFPEV 2810
Query 2968 YLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLL 3027
+ V +V T EYC+ G C+ SEAG+C+S RWV+NN Y+R GV+CG A +L
Sbjct 2811 -ISAGVHIVRTMAMEYCKVGRCDVSEAGLCMSLQPRWVVNNAYFRQQSGVYCGTSAFDLF 2869
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
NM P+ P+GA+DI+ SI+ G ++A+VV+ YY +RFRRAFG+YS V+ N L F++
Sbjct 2870 MNMLLPIFTPVGAVDITTSILMGALLAVVVSMSLYYLLRFRRAFGDYSGVIFTNILAFVL 2929
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIIC 3147
+ VLCL Y LP +Y++++LY T Y +D++ + H+ +++MF +VP W+T+ YI+
Sbjct 2930 NVIVLCLEGPYPMLPSIYAMVFLYATCYFGSDIACMMHVSFLIMFAGVVPLWVTVLYIVV 2989
Query 3148 ISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRY 3207
+ ++H WF S KR V ++F +F++AAL TF+L+KE++L+L+ ++ Y +Y
Sbjct 2990 VLSRHILWFASLCTKRTVQVGDLAFHSFQDAALQTFMLDKEVFLRLKREI--SSDAYFKY 3047
Query 3208 LALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFR 3267
LA+YNKYKY+SG MDT +YREAAC HL AL +SN G D +YQPP+ S+ SA LQ+G
Sbjct 3048 LAMYNKYKYYSGPMDTAAYREAACSHLVMALEKYSNGGGDTIYQPPRCSVASAALQAGLT 3107
Query 3268 KMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNH 3327
+MA PSG VE C+V+V G+ TLNG+WLD+ V CPRHV+C+ +++ NP+Y L +R +N+
Sbjct 3108 RMAHPSGLVEPCLVKVNYGSMTLNGIWLDNFVICPRHVMCSRDELANPDYPRLSMRAANY 3167
Query 3328 NFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSG 3387
+F V +RVIGH+M+ +LKL VD NPKTP Y F+R+ GQ S+LACY+G P+G
Sbjct 3168 DFHVSQNGHNIRVIGHTMEGSLLKLTVDVNNPKTPAYSFIRVSTGQAMSLLACYDGLPTG 3227
Query 3388 VYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGP 3447
VY C +R N T++ SFL GSCGS GF ++ V FCY+H +ELP G H GTD G FYGP
Sbjct 3228 VYTCTLRSNGTMRASFLCGSCGSPGFVMNGKEVQFCYLHQLELPNGTHTGTDFSGVFYGP 3287
Query 3448 FVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQ 3507
F D+Q Q A D TITVNVLAWLYAAV++G+ WFL + + + +FN A+KY + +T
Sbjct 3288 FEDKQVPQLAAPDCTITVNVLAWLYAAVLSGENWFLTKSSISPAEFNNCAVKYMCQSVTS 3347
Query 3508 DHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVT 3567
+ + +L PL+A+TGI+V M ++LK LL G GRTI+GS LEDE TP+D+ RQ GV
Sbjct 3348 ESLQVLQPLAAKTGISVERMLSALKVLLSAGFCGRTIMGSCSLEDEHTPYDIGRQMLGVK 3407
Query 3568 FQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMM 3627
Q + + T W + + ++L+L+Q QW+ L LP + F +
Sbjct 3408 LQGKFQSMFRWTLQWFAIIFVLTILILLQLAQWTFVGALPFTLLLPLIGFVAVCVGFVSL 3467
Query 3628 FVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYAS 3687
+KHKH +L ++LLP AY+N Y P +++ + V+ D +
Sbjct 3468 LIKHKHTYLTVYLLPVAMVTAYYNFQYTPEGVQGYLLSLYNYVNPGRIDVIGTDLLTMLI 3527
Query 3688 AVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 3747
V L++ R V D R+W + + +Y + G+A AIS ++SV +NY+GV
Sbjct 3528 ISVACTLLSVRMVRTDAYSRIWYVCTAVGWLYNCWTGSADTVAISYLTFMVSVFTNYTGV 3587
Query 3748 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
++ A+ +V++ P + +C+++ Y +GY CTCYFG+F L+NR FR T
Sbjct 3588 ACASLYAAQFMVWVLKFLDPTILLLYGRFRCVLVCYLLVGYLCTCYFGVFNLINRLFRCT 3647
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
LG Y+Y+VS+QE RYMNS GLLPP NS A LNIKL G+GG P +V+T+QS M+D+KC
Sbjct 3648 LGNYEYVVSSQELRYMNSHGLLPPTNSWQALMLNIKLAGIGGIPIYRVSTIQSNMTDLKC 3707
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDI 3927
TSVVLLSVLQQLRVESSSKLWA CV+LHN+IL + TEAFE VSLLSVLLS+ GA+++
Sbjct 3708 TSVVLLSVLQQLRVESSSKLWALCVKLHNEILASNSPTEAFEAFVSLLSVLLSLPGAINL 3767
Query 3928 NKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVA 3987
++LC +L+N + LQA+ASEFS+L SY + AQ+AY+ AVA G + LKK++NVA
Sbjct 3768 DELCSSILENNSVLQAVASEFSNLSSYVDYENAQKAYDTAVATGAPASTVNALKKAMNVA 3827
Query 3988 KSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNN 4047
KS D+D A RKLE+M++ AMT MYKQAR+ED+R+KVT+AMQTMLF M+R+LD+DAL+N
Sbjct 3828 KSVLDKDVATTRKLERMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSN 3887
Query 4048 IINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSK 4107
I+NNAR+G VPL +IP T A KL++V+PD++ Y T T TYA + W++ QV DAD K
Sbjct 3888 ILNNARNGVVPLGVIPRTAANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGK 3947
Query 4108 IVQLSEISMDNSPNLAWPLIVTALR--ANSAVKLQNNELSPVALRQMSCAAGTTQTACTD 4165
V ++I+ +NS NLAWPL+VTA R A S VKLQNNEL P +++M+ AG +QTAC
Sbjct 3948 TVNATDITRENSVNLAWPLVVTAQRQQATSPVKLQNNELMPQTVKRMNVVAGVSQTACVT 4007
Query 4166 DNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKV 4225
D A+AYYN TK GR V+A+L+D L +A+ KS G G + ELEPPC+F+ DTPKGP +
Sbjct 4008 D-AVAYYNATKEGRHVMAILADTDGLAFAKVEKSTGDGFVILELEPPCKFMVDTPKGPAL 4066
Query 4226 KYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLA 4285
KYLYF KGL NL RG VLG+LA TVRL AG+ATEV +NS++LS C+F+VD YKDYL
Sbjct 4067 KYLYFTKGLKNLCRGTVLGTLACTVRLHAGSATEVASNSSILSLCSFSVDPEATYKDYLD 4126
Query 4286 SGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDL 4345
+GG PI NCVKML HTGTG AIT P+AN+DQESFGGASCCLYCRCHI+HP G C
Sbjct 4127 NGGSPIGNCVKMLTPHTGTGLAITAKPDANIDQESFGGASCCLYCRCHIEHPGASGVCKY 4186
Query 4346 KGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNR 4402
KGK+VQIP NDP+GF ++N VC VC MW+GYGC C LRE LQ+ D + FLN
Sbjct 4187 KGKFVQIPLVGVNDPIGFCIRNVVCAVCNMWQGYGCPCSSLREINLQARD-ECFLNE 4242
>sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respiratory
syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=1a PE=1 SV=1
Length=4391
Score = 2192 bits (5680), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1249/3281 (38%), Positives = 1852/3281 (56%), Gaps = 187/3281 (6%)
Query 1259 INGNLHPDSATLVSDIDITFLKKDAPYIVGD-VVQEGVLTA-----VVIPTKKAGGTTEM 1312
I G ++ S V ++ P VGD V+ +G A VV P +A +
Sbjct 1156 IAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSL 1215
Query 1313 LAK---ALRKVPTDNYITTYPGQGLNG--------YTVEEAKTVLKKCKSAFYILPSIIS 1361
L+K A+ P +T G+ G Y + EAKT + ++ + S+
Sbjct 1216 LSKCYKAMNAYPL--VVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTI 1273
Query 1362 NEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGAR 1421
+ + L LR + A++ + VC + A ++ K + VD G +
Sbjct 1274 VDIPQSLTFSYDGLRGAIRKAKDYGFTVFVCTDNSANTKVLRNKGVDYTKKFLTVD-GVQ 1332
Query 1422 FYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPD 1481
+Y YTSK T+ ++ N + +++MPLGYV+HGL+L +A +R + VP +++ +
Sbjct 1333 YYCYTSKDTLDDILQQANK-SVGIISMPLGYVSHGLDLIQAGSVVRRVNVPYVCLLANKE 1391
Query 1482 AVTAYNGYLTSSSK--TPEEHFIETISLAGSYKDWSYSG-----QSTQLGIEFLKRGDKS 1534
L S P E FI+ + G Y W Q +L + L D++
Sbjct 1392 Q----EAILMSEDVKLNPSEDFIKHVRTNGGYNSWHLVEGELLVQDLRLN-KLLHWSDQT 1446
Query 1535 V-------YYTSNPTTFHLDGEVITFDNLKTLLSLREVR--TIKVFTTVDNINLHTQVVD 1585
+ Y N T F + T + L R + TI+V TVD +N T V++
Sbjct 1447 ICYKDSVFYVVKNSTAFPFE----TLSACRAYLDSRTTQQLTIEVLVTVDGVNFRTVVLN 1502
Query 1586 MSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAF-EYYHTTDPSFLG 1644
TY Q G + +GAD++ P G + Y+ N +A E Y DP+FL
Sbjct 1503 NKNTYRSQLGCVFFNGADISDTIPDEKQNGHSLYLADNLTADETKALKELYGPVDPTFLH 1562
Query 1645 RYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQI-ELKFNPPALQDAYYRAR 1703
R+ S KWK + + S+K +DNNCYL ++TL + ++KF PALQ A+ + +
Sbjct 1563 RFYSLKAAVHKWKMVVCDKVRSLKLSDNNCYLNAVIMTLDLLKDIKFVIPALQHAFMKHK 1622
Query 1704 AGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLD-SCKRVLNVVCKTCGQQQTTL 1762
G++ +F ALI+AY N T G D + + A L S + V C CG + L
Sbjct 1623 GGDSTDFIALIMAYGNCTFGAPDDASRLLHTVLAKAELCCSARMVWREWCNVCGIKDVVL 1682
Query 1763 KGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGT-- 1820
+G++A Y+G + E + + C CG + + +V+ +P++++S P + + T
Sbjct 1683 QGLKACCYVGVQTVEDLRARMTYVCQCGGERHRQIVEHTTPWLLLSGTPNEKLVTTSTAP 1742
Query 1821 -FTCASEYTG-NYQCGHYKHITSKETLYC-IDGALLTKSSEYKGPITDVFYKENSYTTTI 1877
F + + G GHY H K L D ++K+S++K +TDV + Y++
Sbjct 1743 DFVAFNVFQGIETAVGHYVHARLKGGLILKFDSGTVSKTSDWKCKVTDVLFPGQKYSSDC 1802
Query 1878 KPVTYKLDGVVCTEIDPKLDNYYKKDNSYFT-EQPIDLVPNQPYPNASFDNFKFVCDNIK 1936
V Y LDG TE+DP L +Y KD YFT E P+ P + + N V + +
Sbjct 1803 NVVRYSLDGNFRTEVDPDLSAFYVKDGKYFTSEPPVTYSPATILAGSVYTNSCLVSSDGQ 1862
Query 1937 FADD-----LNQLTGY--KKPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKP 1989
D N L G+ KP +++ +F P +GDV+ ++ Y P +K GA KP
Sbjct 1863 PGGDAISLSFNNLLGFDSSKPVTKKYTYSFLPKEDGDVLLAEFDTYDPIYKNGAMYKGKP 1922
Query 1990 IVWHVNNATNKATY-----KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDL 2044
I+W NKA+Y K N +R ++ P+E N F L E
Sbjct 1923 ILW-----VNKASYDTNLNKFNRASLRQIFDVAPIELENKFTPLSVEST----------- 1966
Query 2045 KPVSEEVVENPTIQKD--VLECNVKTTEVVGDIILKPANNS-LKITEEVGHTDLMAAYVD 2101
PV V+ +Q++ +++C V D + A++S + E + DL YVD
Sbjct 1967 -PVEPPTVDVVALQQEMTIVKCKGLNKPFVKDNVSFVADDSGTPVVEYLSKEDLHTLYVD 2025
Query 2102 -NSSLTIKKPNELSRVLGLKTLATHGL---AAVNSVPWDTIANYAKPFLNK----VVSTT 2153
+ + K N LS +L L T+ + + AA S+ + F K T
Sbjct 2026 PKYQVIVLKDNVLSSMLRLHTVESGDINVVAASGSLTRKVKLLFRASFYFKEFATRTFTA 2085
Query 2154 TNIVTRCLNRV-------------CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTT--- 2197
T V C+ V C +++ F L L + ++ + +K S T
Sbjct 2086 TTAVGSCIKSVVRHLGVTKGILTGCFSFVKMLFMLPLAYFSDSKLGTTEVKVSALKTAGV 2145
Query 2198 IAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSN- 2256
+ N VK ++ S + L+ ++ + +++ V L S+ + VL S+
Sbjct 2146 VTGNVVKQCCTAAVDLSMDKLRRVDWKSTLRLLLMLCTTMVLLSSVYHLYVFNQVLSSDV 2205
Query 2257 ------------------LGMPSYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDS 2297
LG+ S C G Y + + + T+C S C+ CL DS
Sbjct 2206 MFEDAQGLKKFYKEVRAYLGISSACDGLASAY-RANSFDVPTFCANRSAMCNWCLISQDS 2264
Query 2298 LDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVH 2357
+ YP+L+ +Q +S + ++ E LAY+L+T F L LA + FF+ ++
Sbjct 2265 ITHYPALKMVQTHLSHYVLNIDWLWFAFETGLAYMLYTSAFNWLLLAGTLHYFFAQTSIF 2324
Query 2358 FISNSW------LMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMM 2411
S+ WL ++ P++ +VRMY A + + K Y HV++GC + C++
Sbjct 2325 VDWRSYNYAVSSAFWLFTHI----PMAGLVRMYNLLACLWLLRKFYQHVINGCKDTACLL 2380
Query 2412 CYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVAR 2471
CYKRNR TRVE +T+V G +R+FY+ ANGG FC+ HNWNCV+CDT G+TFI +EVA
Sbjct 2381 CYKRNRLTRVEASTVVCGGKRTFYITANGGISFCRRHNWNCVDCDTAGVGNTFICEEVAN 2440
Query 2472 DLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLR--- 2528
DL+ +RPIN TD+S Y VDSVTVK + + + GQ YER L F NLD L+
Sbjct 2441 DLTTALRRPINATDRSHYYVDSVTVKETVVQFNYRRDGQPFYERFPLCAFTNLDKLKFKE 2500
Query 2529 -ANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVA 2587
T G N I++D + +ES A+SA VYYSQ++C+ ILL+D +LV+ VGDS+E+A
Sbjct 2501 VCKTTTGIPEYNFIIYDSSDRGQESLARSACVYYSQVLCKSILLVDSSLVTSVGDSSEIA 2560
Query 2588 VKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDV 2646
KMFD++VN+F S +NV +KL+ L++TA + + + +VL+TFI AAR V+SDV
Sbjct 2561 TKMFDSFVNSFVSLYNVTRDKLEKLISTARDGVRRGDNFHSVLTTFIDAARGPAGVESDV 2620
Query 2647 ETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKS 2706
ET ++V+ ++ +H+ DI++T +S NNY+ +Y K ++++ DLG+ IDC+A +N V ++
Sbjct 2621 ETNEIVDSVQYAHKHDIQITNESYNNYVPSYVKPDSVSTSDLGSLIDCNAASVNQIVLRN 2680
Query 2707 HNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIV 2766
N A IWN +M LS+ L++QIR A +K NL F+LT + R N+++ + KIV
Sbjct 2681 SNGACIWNAAAYMKLSDALKRQIRIACRKCNLAFRLTTSKLRANDNILSVR--FTANKIV 2738
Query 2767 NN---W--------LKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGG 2815
W LK + T++ A + YL P M + I+ +K +D G
Sbjct 2739 GGAPTWFNALRDFTLKGYVLATIIVFLCAVLMYLCLPTFSMVPVEFYEDRILDFKVLDNG 2798
Query 2816 VTRDIASTDTCFANKHADFDTWFSQR-GGSYTNDKACPLIAAVITREVGFVVPGLPGTIL 2874
+ RD+ D CFANKH F W+ + GG Y N CPL AVI G +P +P T L
Sbjct 2799 IIRDVNPDDKCFANKHRSFTQWYHEHVGGVYDNSITCPLTVAVIAGVAGARIPDVP-TTL 2857
Query 2875 RTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCY 2934
N + F+ RVF+ G++CYTP I Y F+ S C+L +ECT+F+DA G+ PYC+
Sbjct 2858 AWVNNQIIFFVSRVFANTGSVCYTPIDEIPYKSFSDSGCILPSECTMFRDAEGRMTPYCH 2917
Query 2935 DTNVLEGSVAYESLRPDTRYVLMDGSI-IQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
D VL G+ AY +RP RY L DG++ I+FP E ++R+ T ++YCR G+CE ++
Sbjct 2918 DPTVLPGAFAYSQMRPHVRYDLYDGNMFIKFPEVVFESTLRITRTLSTQYCRFGSCEYAQ 2977
Query 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
GVC++T+G W + ND++ + PGV+CG D ++++ + L QPI ++ S+V G +
Sbjct 2978 EGVCITTNGSWAIFNDHHLNRPGVYCGSDFIDIVRRLAVSLFQPITYFQLTTSLVLGIGL 3037
Query 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
+T L YY + +RAF +Y+ + +++ +C Y+ +Y Y T
Sbjct 3038 CAFLTLLFYYINKVKRAFADYTQCAVIAVVAAVLNSLCICFVASIPLCIVPYTALYYYAT 3097
Query 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV-VF-NGVS 3171
FY TN+ +F+ H+ W +MF P+VP W+T Y + + +HF+W + + K+ V VF +G
Sbjct 3098 FYFTNEPAFIMHVSWYIMFGPIVPIWMTCVYTVAMCFRHFFWVLAYFSKKHVEVFTDGKL 3157
Query 3172 FSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAAC 3231
+F++AA F++NK+ Y LR+ L Y+R+L L+NKYKYFSGAM+T +YREAA
Sbjct 3158 NCSFQDAASNIFVINKDTYAALRNS--LTNDAYSRFLGLFNKYKYFSGAMETAAYREAAA 3215
Query 3232 CHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLN 3291
CHLAKAL +S +GSD+LYQPP SITS VLQSG KM+ PSG VE CMVQVTCG+ TLN
Sbjct 3216 CHLAKALQTYSETGSDLLYQPPNCSITSGVLQSGLVKMSHPSGDVEACMVQVTCGSMTLN 3275
Query 3292 GLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQ---AGNVQLRVIGHSMQNC 3348
GLWLD+ V+CPRHV+C ++ + +PNY+ LLI +NH+F VQ LRV+GH+MQ
Sbjct 3276 GLWLDNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVVGHAMQGT 3335
Query 3349 VLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSC 3408
+LKL VD ANP TP Y F ++PG FSVLACYNG P+G + MRPN+TIKGSFL GSC
Sbjct 3336 LLKLTVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCGSC 3395
Query 3409 GSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVL 3468
GSVG+ + ++FCYMH MEL G H G+ +G YG F+D+Q Q TD +VNV+
Sbjct 3396 GSVGYTKEGSVINFCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVNVV 3455
Query 3469 AWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY-EPLTQDHVDILGPLSAQTGIAVLDM 3527
AWLYAA++NG WF+ T++ FN A+ + E + VD+L + +TG+A+ +
Sbjct 3456 AWLYAAILNGCAWFVKPNRTSVVSFNEWALANQFTEFVGTQSVDML---AVKTGVAIEQL 3512
Query 3528 CASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTI 3587
++++L G G+ ILGS +LEDEFTP DV Q GV QS V++ GT HWL T+
Sbjct 3513 LYAIQQLY-TGFQGKQILGSTMLEDEFTPEDVNMQIMGVVMQSGVRKVTYGTAHWLFATL 3571
Query 3588 LTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATV 3647
+++ ++++Q+T+++L+ +L+E + AF M+ VKHKH FL LFLLP +
Sbjct 3572 VSTYVIILQATKFTLWNYLFETIPTQLFPLLFVTMAFVMLLVKHKHTFLTLFLLPVAICL 3631
Query 3648 AYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDD 3703
Y N+VY P +S ++ + WL + + D +Y S ++L+++ R
Sbjct 3632 TYANIVYEPTTPISSALIAVANWLAPTNAYMRTTH-TDIGVYISMSLVLVIVVKRLYNPS 3690
Query 3704 GARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCV 3763
+ L + + +Y G A I+ + ++TS+Y+ V + LA+ +
Sbjct 3691 LSNFALALCSGVMWLYTYSIGEA-SSPIAYLVFVTTLTSDYTITVFVTVNLAKVCTYAIF 3749
Query 3764 EYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYM 3823
Y P + ++ I+L+Y LG+ CTCYFG+F LLN R +GVYD+ VSTQEFR+M
Sbjct 3750 AYSPQLTLVFPEVKMILLLYTCLGFMCTCYFGVFSLLNLKLRAPMGVYDFKVSTQEFRFM 3809
Query 3824 NSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVES 3883
+ L P+NS +A LN KL+G+GG PCIKVA +QSK++D+KCTSVVLLSVLQQL +E+
Sbjct 3810 TANNLTAPRNSWEAMALNFKLIGIGGTPCIKVAAMQSKLTDLKCTSVVLLSVLQQLHLEA 3869
Query 3884 SSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQA 3943
+S+ WA CV+ HNDIL A D +EAFEK VSL + L++ G VD++ L ++ D + LQA
Sbjct 3870 NSRAWAFCVKCHNDILAATDPSEAFEKFVSLFATLMTFSGNVDLDALASDIFDTPSVLQA 3929
Query 3944 IASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKLE 4002
SEFS L ++A AQ+AY++A+ +GD S VLK L+K++N+AK+ +++D A+ RKLE
Sbjct 3930 TLSEFSHLATFAELEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKNAYEKDKAVARKLE 3989
Query 4003 KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII 4062
+MADQAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN II+NAR+GC+PL++I
Sbjct 3990 RMADQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIPLSVI 4049
Query 4063 PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL 4122
PL + KL VVIPD+ + + YA ALW+I + + D++IV+ S++ +D++ NL
Sbjct 4050 PLCASNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDV-VDSNENL 4108
Query 4123 AWPLIVTALRAN-SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFV 4181
WPL++ RA+ SAVKLQNNE+ P L+ M +AG QT C + ++LAYY +G + +
Sbjct 4109 TWPLVLECTRASTSAVKLQNNEIKPSGLKTMVVSAGQEQTNC-NTSSLAYYEPVQGRKML 4167
Query 4182 LALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGM 4241
+ALLSD LKWAR DG ++ EL+PPC+F+ PKGP+++YLYF+K LNNL+RG
Sbjct 4168 MALLSDNAYLKWARVEGKDGFVSV--ELQPPCKFLIAGPKGPEIRYLYFVKNLNNLHRGQ 4225
Query 4242 VLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTH 4301
VLG +AATVRLQAG+ TE +NS+VLS F VD KAY D++ +GG P+TNCVKML
Sbjct 4226 VLGHIAATVRLQAGSNTEFASNSSVLSLVNFTVDPQKAYLDFVNAGGAPLTNCVKMLTPK 4285
Query 4302 TGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPV 4361
TGTG AI+V PE+ DQE++GGAS CLYCR HI+HP+ G C KGK+VQIP C DPV
Sbjct 4286 TGTGIAISVKPESTADQETYGGASVCLYCRAHIEHPDVSGVCKYKGKFVQIPAQCVRDPV 4345
Query 4362 GFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNR 4402
GF L NT C VC W GYGC+CD LR+ L + +FLN
Sbjct 4346 GFCLSNTPCNVCQYWIGYGCNCDSLRQAALPQSKDSNFLNE 4386
Score = 275 bits (703), Expect = 1e-71, Method: Compositional matrix adjust.
Identities = 298/1189 (25%), Positives = 516/1189 (43%), Gaps = 143/1189 (12%)
Query 101 GETLGVLVPHVGEIPVAYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQEN 160
G+ +G+ P+ E+ + +LLRK G GG+ Y ++ + + +DF+ +
Sbjct 123 GKPIGMFFPYDIELVTGKQNILLRKYGR---GGYHYTP--FHYERDNTSCPEWMDDFEAD 177
Query 161 WNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCT-LSEQL 219
K++ + L+++L GG T VD CG DG P+ L+A+ G + +
Sbjct 178 PKGKYA----QNLLKKLIGGDVTP-VDQYMCGVDGKPISAYAFLMAKDGITKLADVEADV 232
Query 220 DFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNS 279
G + + + + W+ ER + Y Q+ F I + D P++ F L
Sbjct 233 AARADDEGFITLKNNLYRLVWHVERKDVPYPKQSIFTINSVVQKDGVENTPPHY-FTLGC 291
Query 280 IIKTIQPR----------VEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGET 329
I T+ PR +++K L F G+ S + S ++C CG
Sbjct 292 KILTLTPRNKWSGVSDLSLKQKLLYTFYGK-------ESLENPTYIYHSAFIECGSCGND 344
Query 330 SWQTGDFVKATCEFCGTENLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGP--EHSLAE 386
SW TG+ ++ CG + + G + NA++ CP +HS+A+
Sbjct 345 SWLTGNAIQGFACGCGASYTANDVEVQSSGMIKPNALLCATCPFAKGDSCSSNCKHSVAQ 404
Query 387 ---YHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGS 443
Y +E I T+ FGG ++Y GC Y+VPRA + + + G
Sbjct 405 LVSYLSER-CNVIADSKSFTLIFGGVAYAYFGCEEGTMYFVPRAKSVVSRIGDSIF-TGC 462
Query 444 EGLNDNLLEI----LQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAF 499
G + + +I L++ + ++N VG+F +N+ + IL+ + + + +KG+
Sbjct 463 TGSWNKVTQIANMFLEQTQHSLNFVGEFVVNDVVLAILSGTTTNVDKIRQLLKGVTLDKL 522
Query 500 KQIVESCGNFKVTKGKAKKGAWNIG----EQKSILSPLYAFAS--EAARVVRSIFSRTLE 553
+ + + VT G A N+G + +I +P E+ + V +I +
Sbjct 523 RDYLADY-DVAVTAGPFMDNAINVGGTGLQYAAITAPYVVLTGLGESFKKVATIPYKVCN 581
Query 554 TAQNSV-----RVLQKAAITILD-GISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQ 607
+ ++++ VL + +D G+S +S L D + DL+ V Y ++Q
Sbjct 582 SVKDTLTYYAHSVLYRVFPYDMDSGVSSFSELLFDCV----DLS----VASTYFLVRLLQ 633
Query 608 -LTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
T +++ I + + +LD E + FL D + + A V
Sbjct 634 DKTGDFMSTIITSCQTAVSKLLDTCFEATEATFNFLLDLAGLFRIFLRNAYVYTSQGFVV 693
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKA-LNLGETFVTHSKGLYRKCVKSR- 724
++ V+ L+NK + L + G+ + A + G + G Y CV ++
Sbjct 694 VNGKVSTLVKQVLDLLNKGMQLLHTKVSWAGSNISAVIYSGRESLIFPSGTYY-CVTTKA 752
Query 725 ----EETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDL-----QPLEQPTSEAVE 775
++ +++P + K+ + G PT+ T V + ++ LEQ + +
Sbjct 753 KSVQQDLDVILPGEFSKKQL---GLLQPTDNSTTVSVTVSSNMVETVVGQLEQTNMHSPD 809
Query 776 APLVGTPVCINGLMLLEIKDTEKYCALAP---NMMVTNNTFTLKGGAPTK-VTFGDDTVI 831
+VG V I+ + + K+ + + A P N F LKGGAP K V FG D V
Sbjct 810 V-IVGDYVIISEKLFVRSKEEDGF-AFYPACTNGHAVPTLFRLKGGAPVKKVAFGGDQVH 867
Query 832 EVQGYKSVNITFELDERIDKVL-NEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL 890
EV +SV + + + +D +L + + V+ + EFA VV + V L + +
Sbjct 868 EVAAVRSVTVEYNIHAVLDTLLASSSLRTFVVDKSLSIEEFADVVKEQVSDLLVKLLRGM 927
Query 891 TPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEE---EEFEPSTQY 947
DLD++ A Y F+ G+ +S M S +P + DEE + E EE E
Sbjct 928 PIPDFDLDDFIDAPCYCFNAEGDASWSSTMIFSLHPVECDEECSEVEASDLEEGESECIS 987
Query 948 EYGTE----------DDY-----QGKPL-EFGATSAALQPEEEQEEDWLDDDSQQTVGQQ 991
E TE D++ + PL E + ++Q E + E ++D +Q +
Sbjct 988 ETSTEQVDVSHEISDDEWAAAVDEAFPLDEAEDVTESVQEEAQPVEVPVEDIAQVVIADT 1047
Query 992 DGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIE--------------------------- 1024
+T + VEV PQ+ ++L QTI+
Sbjct 1048 L----QETPVVSDTVEVPPQV-VKLPSEPQTIQPEVKEVAPVYEADTEQTQSVTVKPKRL 1102
Query 1025 -----VNSFSGYLK--LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
V+ S + +T+ V I D ++ AK +V+VNAAN +LKHGGG+AGA+N
Sbjct 1103 RKKRNVDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHGGGIAGAINA 1162
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
A+ A+Q ESD+YI GPL+VG S +L GH+LAK+ LHVVGP+ +D+ LL Y+
Sbjct 1163 ASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSLLSKCYKA 1222
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKL 1186
N + +++ PL+SAGIFG P S + +T V + V +++Y L
Sbjct 1223 MNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSL 1271
>sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus
HKU5 OX=694008 GN=1a PE=3 SV=1
Length=4481
Score = 2172 bits (5629), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1223/3125 (39%), Positives = 1809/3125 (58%), Gaps = 140/3125 (4%)
Query 1391 VCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPL 1450
+C + A ++ + + + VD G ++Y Y+SK + +I N + + MP+
Sbjct 1379 ICTDQSANAKLLKGRGVDLTKKTQTVD-GVKYYLYSSKDPLTDIITAANAC-KGICAMPI 1436
Query 1451 GYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGS 1510
GYVTHGL+L +A + ++ + VP ++S D V N + + +TPE+ FI T+ G
Sbjct 1437 GYVTHGLDLAQAGQQVKKITVPYVCLLASKDQVPILNSDV--AVQTPEQSFINTVIANGG 1494
Query 1511 YKDWSY-SGQSTQLGIEF---LKRGDKSVYYTSNPTTFHLDGEV-ITFDNL---KTLLSL 1562
Y W +G+ G+ + L D+++ Y N + + G++ + FD+L +T L+
Sbjct 1495 YHCWHLVTGELIVKGVSYRKLLNWSDQTICYADN-KFYVVKGQIALPFDSLEKCRTYLTS 1553
Query 1563 R--EVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
R + + + V T+D +N T V++ + TY Q G + G+D++ P G+ Y+
Sbjct 1554 RAAQQKNVDVLVTIDGVNFRTVVLNNTTTYRVQLGSVFYKGSDISDTIPTEKMSGEAVYL 1613
Query 1621 LPN-DDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATA 1679
N + + E Y T D +FL RY S L KKWKY +G+ S+K NNCY+
Sbjct 1614 ADNLSEAEKAVLSEVYGTADTAFLHRYYSLLALVKKWKYTVHDGVKSLKLNSNNCYVNVT 1673
Query 1680 LLTLQQI-ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQH 1738
+L L + E+KF PALQ AY + + G++ F ALI+AY + T GE D + +
Sbjct 1674 MLMLDMLKEIKFIVPALQAAYLKHKGGDSTEFIALIMAYGDCTYGEPDDASRLLHTILSK 1733
Query 1739 ANLDS-CKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYL 1797
A L + K V C CG Q TT G++A +Y+G S ++ + C CG + L
Sbjct 1734 AELTTQAKMVWRQWCNVCGVQDTTTTGLKACIYVGMNSLDELHATHEECCQCGDVRKRQL 1793
Query 1798 VQQESPFVMMSAPPAQYELKHGTFTCASEYTG-------NYQCGHYKHITSKETL-YCID 1849
V+ +P++++S + + + +YT GHY H+ K+ L Y D
Sbjct 1794 VEHNAPWLLLSGLNEAKVMTPTSQSAGPDYTAFNVFQGVETSVGHYLHVRVKDNLLYKYD 1853
Query 1850 GALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTE 1909
L+K+S+ K +TDV+Y + Y+ V Y LDG ++DP L +Y KD YFT+
Sbjct 1854 SGSLSKTSDMKCKMTDVYYPKQRYSADCNVVVYSLDGNTWADVDPDLSAFYMKDGKYFTK 1913
Query 1910 QPI------DLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGY--KKPASRELKVTFFP 1961
+P+ ++ Y N+ + + N L G+ KP S++L +FFP
Sbjct 1914 KPVIEYSPATILSGSVYTNSCLVGHDGTIGSDAISSSFNNLLGFDNSKPVSKKLTYSFFP 1973
Query 1962 DLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVET 2021
D GDV+ +Y Y P +K GA L KPI+W N+ + A K N +R ++ PV
Sbjct 1974 DFEGDVILTEYSTYDPIYKNGAMLHGKPILWVNNSKFDSALNKFNRATLRQVYDIAPVTL 2033
Query 2022 SNSFDVLKSEDAQGMDNLAC-EDLKPVSE-EVVENPTIQKDVLECNVKTTEVVGD---II 2076
N + VL+ Q ++ A ED KP S +V E+ + +++C V D +
Sbjct 2034 ENKYTVLQDNQIQQVEVEAPKEDAKPQSPVQVAEDIDNKLPIIKCKGLKKPFVKDGYSFV 2093
Query 2077 LKPANNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPW 2135
P + + + +G DL A YVD N L + K N S + + T+ L+ + +
Sbjct 2094 NDP--QGVNVIDTLGIDDLRALYVDRNLRLIVLKENNWSALFNIHTVEKGDLSVIAASGS 2151
Query 2136 DT----IANYAKPFLNKVVSTTTNIVT---RCLNRVCTNYMP------YFFTLLLQLC-- 2180
T I A + S T N+ T + L R+ N + F LL L
Sbjct 2152 ITRRVKILLGASSLFAQFASVTVNVTTAMGKALGRMTRNVITNTGIIGQGFALLKMLLIL 2211
Query 2181 --TFTRSTN-SRIKASMPTTIAKNTVKS-VGKFCLEASFNYLKSPNFSKLINIIIWFLLL 2236
TF +S N S +K + V + V K C A+++ L F ++ LL
Sbjct 2212 PFTFWKSKNQSTVKVEVGALRTAGIVTTNVVKQCASAAYDVLVV-KFKRIDWKSTLRLLF 2270
Query 2237 SVC------------------LGSLIYSTAALGVLM------SNLGMPSYCTGYREGYLN 2272
+C L S + A G+L S LG+ S C G E Y N
Sbjct 2271 LICTTGLLLSSLYYLFLFHQVLTSDVMLDGAEGMLATYRELRSYLGIHSLCDGMVEAYRN 2330
Query 2273 STNVTIATYCTG-SIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAY 2331
+ + +C+ S C+ CL G DSL Y + + IQ ++S+ ++ V E+ LAY
Sbjct 2331 -VSYDVNDFCSNRSALCNWCLIGQDSLTRYSAFQMIQTHVTSYVINIDWVWFVMEFALAY 2389
Query 2332 ILFTRFFYVLGLAAIMQLFFSYFA--VHFISNSWLMWLIINLVQMAPISAMVRMYIFFAS 2389
+L+T F VL L Q FFSY V++ S ++L+ V P+ +VR+Y F A
Sbjct 2390 VLYTSTFNVLLLVVSSQYFFSYTGAFVNWRSYNYLVSGYFFCVTHIPLLGLVRIYNFLAC 2449
Query 2390 FYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHN 2449
+++ + Y HV++GC + C++CYKRNR TRVE +T+V G +R+FY+ ANGG FC HN
Sbjct 2450 LWFLRRFYNHVINGCKDTACLLCYKRNRLTRVEASTVVCGSKRTFYIVANGGTSFCCRHN 2509
Query 2450 WNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAG 2509
WNCV+CDT G+TFI +EVA DL+ +R + PTD+S Y V+SVTVK+ + L++ + G
Sbjct 2510 WNCVDCDTAGIGNTFICEEVANDLTTSLRRLVKPTDKSHYYVESVTVKDSVVQLHYSREG 2569
Query 2510 QKTYERHSLSHFVNLDNLRAN---NTKGSLP-INVIVFDGKSKCEESSAKSASVYYSQLM 2565
YER+ L +F NLD L+ T +P N +++D + +E+ A+SA VYYSQ++
Sbjct 2570 ASCYERYPLCYFTNLDKLKFKEVCKTPTGIPEHNFLIYDSSDRGQENLARSACVYYSQVL 2629
Query 2566 CQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVS 2625
+P+LL+D +V+ VGDS E+A KM D+YVN+F S F V +KL LVATA + +
Sbjct 2630 SKPMLLVDSNMVTTVGDSREIASKMLDSYVNSFISLFGVNRDKLDKLVATARDCVKRGDD 2689
Query 2626 LDNVLSTFISAAR-QGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMT 2684
V+ TF AAR V+SDVET +V+ L+ +++ D+++T + NNY+ +Y K +++
Sbjct 2690 FQTVIKTFTDAARGPAGVESDVETSSIVDALQYAYKHDLQLTTEGFNNYVPSYIKPDSVA 2749
Query 2685 PRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTC 2744
DLG ID +A +N ++ N A IWN D+M LS+ L++QIR A +K N+PF+LT
Sbjct 2750 TADLGCLIDLNAASVNQTSIRNANGACIWNSSDYMKLSDSLKRQIRIACRKCNIPFRLTT 2809
Query 2745 ATTRQVVNVVTTKIA---LKGGKIVNNWL--------KQLIKVTLVFLFVAAIFYLITPV 2793
+ R N+++ K + L GG WL K VTLV +A + YL P
Sbjct 2810 SRLRSADNILSVKFSATKLSGG--APKWLLKLRDFTWKSYCVVTLVVFAMAVLSYLCLPA 2867
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQR-GGSYTNDKACP 2852
MS+ + I+ YK ++ G+ RDI +DTCFANK+ F WF++ GG + ND +CP
Sbjct 2868 FNMSQVSFHEDRILTYKVVENGIIRDITPSDTCFANKYQSFSKWFNEHYGGLFNNDISCP 2927
Query 2853 LIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSA 2912
+ AVI G VP LP + L F+ RVF++ N+CYTP+ I Y F+ S
Sbjct 2928 VTVAVIAGVAGARVPNLPANVAWVGRQIVL-FVSRVFASSNNVCYTPTAEIPYERFSDSG 2986
Query 2913 CVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSI-IQFPNTYLEG 2971
CVLA+ECT+F+DA GK PYCYD VL G+ AY+ ++P RY + D + I+FP E
Sbjct 2987 CVLASECTLFRDAEGKINPYCYDPTVLPGASAYDQMKPHVRYDMYDSDMYIKFPEVVFES 3046
Query 2972 SVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMF 3031
++R+ T + YCR G+CE + GVC++T+G W + ND+Y + PGV+CG + +++ +
Sbjct 3047 TLRITKTLATRYCRFGSCEDANEGVCITTNGSWAIYNDHYANKPGVYCGDNYFDIVRRLG 3106
Query 3032 TPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTV 3091
L QP+ +S S+ G ++ I +T YY + +RA +Y+ L++
Sbjct 3107 LSLFQPVTYFQLSTSLALGVMLCIFLTIAFYYVNKVKRALADYTQCAVVAVAAALLNSLC 3166
Query 3092 LCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTK 3151
LC L Y+ +Y Y TFYLT + +F+ H+ W VMF +VP W+ AYI+ + +
Sbjct 3167 LCFVVSNPLLVLPYTALYYYATFYLTGEPAFVMHVSWFVMFGTVVPIWMVFAYIVGVCLR 3226
Query 3152 HFYWFFSNYLKRRV-VF-NGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQ--YNRY 3207
H W + + K+ V VF +G +F++AA F++NK+ Y+ LR+ + TQ YNRY
Sbjct 3227 HLLWVMAYFSKKHVEVFTDGKLNCSFQDAAANIFVINKDTYVALRNSI----TQDSYNRY 3282
Query 3208 LALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFR 3267
L+++NKYKY+SGAMDT SYREA+ HL KAL +S +GSDVL+QPP S+TS+VLQSG
Sbjct 3283 LSMFNKYKYYSGAMDTASYREASAAHLCKALQVYSETGSDVLFQPPNCSVTSSVLQSGLV 3342
Query 3268 KMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNH 3327
KMA PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+ LL+ K+N
Sbjct 3343 KMAAPSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDALLVSKTNL 3402
Query 3328 NFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGS 3384
+F+VQ LRV+GH+M +LKL V++ANP+TP Y F ++PG +FSVLACYNG
Sbjct 3403 SFIVQKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFSVLACYNGR 3462
Query 3385 PSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNF 3444
P+GV+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H G +G
Sbjct 3463 PTGVFMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHTGCAFDGVM 3522
Query 3445 YGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY-E 3503
YG F DRQ Q +D T+N++AWLYAA++NG WF+ T + FN AM + E
Sbjct 3523 YGAFEDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEWAMSNQFTE 3582
Query 3504 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 3563
+ VD+L + +TG++V + ++ + L G G+TILG+++LEDEFTP DV Q
Sbjct 3583 FIGTQSVDML---AHKTGVSVEQLLYAI-QTLHKGFQGKTILGNSMLEDEFTPDDVNMQV 3638
Query 3564 SGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSA 3623
GV QS VKR G HWL T+L + + +Q T+++++ +L+E L ++ + A
Sbjct 3639 MGVVMQSGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLTPLVLCVMA 3698
Query 3624 FAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKL 3679
M+ VKHKH FL LFLLP+ + Y N+VY P +S ++ + WL+ +
Sbjct 3699 CVMLTVKHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPASVYMRTTH- 3757
Query 3680 KDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIIS 3739
D +Y S L ++ R + + L + + Y G+ ++ + +
Sbjct 3758 TDLGVYLSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPLTYLMFLTT 3816
Query 3740 VTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCL 3799
+TS+Y+ V + +A+ + Y P ++ ++L+Y +GYFCT YFG+F L
Sbjct 3817 LTSDYTVTVFLAVNVAKFFARVVFLYAPHAGFIFPEVKLVLLMYLAVGYFCTVYFGVFSL 3876
Query 3800 LNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 3859
LN R+ LGVYDY VSTQEFRY+ GL P+NS +A +LN+KL+G+GG PCIK+A+VQ
Sbjct 3877 LNLKLRVPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTPCIKIASVQ 3936
Query 3860 SKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLL 3919
SK++D+KCTSVVLLSVLQQL +E++SK WA CV+LHNDIL A D TEAF+ V L + L+
Sbjct 3937 SKLTDLKCTSVVLLSVLQQLHLEANSKAWAHCVKLHNDILAATDPTEAFDNFVCLFATLM 3996
Query 3920 SMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLK 3978
S VD+ L ++LD+ + LQA SEFS L SYA AQ +Y++A+ +GD S VLK
Sbjct 3997 SFSANVDLEALASDLLDHPSVLQATLSEFSHLASYAELEAAQSSYQKALNSGDASPQVLK 4056
Query 3979 KLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLR 4038
L+K++N+AK+ +++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++
Sbjct 4057 ALQKAVNIAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIK 4116
Query 4039 KLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEI 4098
KLDND LN +I+NAR+GCVPL+++PL + KL VVIPD + + +YA ALW+I
Sbjct 4117 KLDNDVLNGVISNARNGCVPLSVVPLCASNKLRVVIPDITIWNKVVTWPSLSYAGALWDI 4176
Query 4099 QQVVDADSKIVQLSEISMDNSPNLAWPLIVTALR-ANSAVKLQNNELSPVALRQMSCAAG 4157
+ + D ++V+ S+++ N +L WPL++ R A+SAV LQNNE+ P L+ M +AG
Sbjct 4177 SLINNVDGEVVKSSDVTETNE-SLTWPLVLECTRAASSAVTLQNNEIRPSGLKTMVVSAG 4235
Query 4158 TTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVT 4217
C + ++LAYY +G + ++ +LS+ LKWA+ DG I EL+PPC+F+
Sbjct 4236 IDHANC-NTSSLAYYEPVEGRKMLMGILSENAHLKWAKVEGRDGFVNI--ELQPPCKFLI 4292
Query 4218 DTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAA 4277
PKGP+V+YLYF+K LNNL+RG +LG +AATVRLQAG+ TE NS+VLS F+VD
Sbjct 4293 AGPKGPEVRYLYFVKNLNNLHRGQLLGHIAATVRLQAGSNTEFAINSSVLSAVTFSVDPG 4352
Query 4278 KAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHP 4337
KAY D++ +GG P+TNCVKML TGTG A++V PEAN DQ+++GGAS CLYCR HI+HP
Sbjct 4353 KAYLDFVNAGGAPLTNCVKMLTPKTGTGIAVSVKPEANADQDTYGGASVCLYCRAHIEHP 4412
Query 4338 NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQ 4397
+ G C KGK+VQ+P DPVGF L+NT C VC W G+GC+CD LR + +
Sbjct 4413 DVTGVCKFKGKFVQVPLHI-RDPVGFCLQNTPCNVCQFWIGHGCNCDALRGTTIPQSKDS 4471
Query 4398 SFLNR 4402
+FLN
Sbjct 4472 NFLNE 4476
Score = 178 bits (451), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 250/1066 (23%), Positives = 445/1066 (42%), Gaps = 91/1066 (9%)
Query 13 HVQLSLPVLQVRDVLVR---GFGDSVEEVLSEARQHLKDGTCGLV--EVEKGVLPQLEQP 67
HV L + D++++ F D E + L G+ L + KG + L P
Sbjct 28 HVSLKASLCDAGDLVLKISPWFMDG-ESAYKHVSEQLSKGSKLLFVPQTLKGFIRHLPGP 86
Query 68 YVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETL-----GVLVPHVGEIPVAYRKVL 122
V++ MV +A G G TL G+ P ++ + L
Sbjct 87 RVYLVERLTGGTYSDPFMVNQLAYQNAAGEGVIGTTLQGKRVGMFFPFDADLVTGEFQFL 146
Query 123 LRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAY 182
LRK KG GG+ + D + PY D + ++ L+++L GG +
Sbjct 147 LRK---KGFGGNRFR------DAPWDYNWTPYSDLMDALEADPCGKYSQSLLKKLVGGDF 197
Query 183 TRYVDNNFCGPDGYPLECIKDLLARAG--KASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
T +D CG +G P+ L+A G K + +E D+ R + + + I W
Sbjct 198 TP-IDQYMCGKNGKPIAEFAALMASEGITKLADVEAEVKSRTDSDRYI-VFKNKLYRIVW 255
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+R + +Y Q+ F + + DT + P F + S I+ I P + +
Sbjct 256 NVQRKDVAYSKQSAFTMNSIVQLDTME-DVPRHSFTIGSEIQVIAPSTAVQANGHLNLKQ 314
Query 301 RSVYPV---ASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKE-GATT 356
R +Y + +E N + S + C CG+ SW TG+ V+ CG + +
Sbjct 315 RLLYAFYGKQAVSEPNYIYHSAYVDCTSCGKGSWLTGNAVQGFACDCGAHYCANDVDLQS 374
Query 357 CGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRT--IAFGGCVFSYV 414
G + +NAV+ CP + E +H+L + + K + G+T + +GG +++Y+
Sbjct 375 SGLVRKNAVLLTTCPCNKDGEC--KHTLPQLVSMMTDKCDVEVVGKTFILTYGGVIYAYM 432
Query 415 GCHNKCAYWVPRASA---NIG-CNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLN 470
GC +++PRA + IG TG G S+ L L++ + IN V +F L
Sbjct 433 GCSGGTMHFIPRAKSCVSKIGDAIFTGCTGTWSKVCETANL-FLERAQHAINFVNEFVLT 491
Query 471 EEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSIL 530
E + +L+ ++S + + ++ + + G + VT G +G N+G
Sbjct 492 ETVVALLSGTTSSIEELRDLCRNATFEKVRDYLTPRG-WIVTMGSYIEGVINVGAAGVCN 550
Query 531 SPLYA-----------FASEAARVVR--SIFSRTLETAQNSV--RVLQKAAITILDGISQ 575
+ L A F AA + S TL+ +S+ RV I ++
Sbjct 551 AALNAPFIVLSGLGESFKKVAATPWKLCSSLRETLDHYADSITYRVF---PYDIPCDVTD 607
Query 576 YSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKF 635
Y+ L+D + T A V Y+ V QLT+ +F + + + +
Sbjct 608 YTALLLDCAVLTGASA---YFVARYVDEKVEQLTNL----VFSSCQSAVAAFVQACMSTY 660
Query 636 KEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIII 695
K +F+ D + ++K +S V + ++ F +++K + L ++
Sbjct 661 KATAKFISDMFTLIKVVSERLYVYTSVGFVVVGDYSSQLLKQFMHILSKAMQLLHTTVSW 720
Query 696 GGAKLKAL--NLGETFVTHSKGLYRKCVKSR---EETGLLMPLK-APKEIIFLE----GE 745
G+KL ++ N ++ V S Y + R ++ L++P + K+I LE
Sbjct 721 AGSKLPSVVYNGRDSLVFPSGTYYCVSTQGRSLQDQFDLVIPGDLSKKQIGILEPTPNST 780
Query 746 TLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCI-NGLMLLEIKDTEK-YCALA 803
T+ ++ T V + G L+P ++ + E V VG V I N + + ++D+E + L
Sbjct 781 TVDKKINTNVVEVVVGQLEPTKEHSPELV----VGDYVIISNKIFVRSVEDSETVFYPLC 836
Query 804 PNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSVNITFELDERIDKVL-NEKCSAYT 861
+ + F LKGGAP K V FG + E+ +SV++ +++ +D +L + + +T
Sbjct 837 TDGKIVPTLFRLKGGAPPKGVKFGGEQTKEITAVRSVSVDYDVHPVLDALLAGSELATFT 896
Query 862 VELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMY 921
VE V +F VV D VI+ L + G DL++++ Y+++ G+ +S M
Sbjct 897 VEKDLPVKDFVDVVKDEVIELLSKLLRGYNVDGFDLEDFADTPCYVYNAEGDLAWSSTMT 956
Query 922 CSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLD 981
S P +E EEE D + E E ++ ED+ + A A+ P E+ + D L
Sbjct 957 FSVNPVEEVEEECDDDYVEDEYLSEEMLVEEDEN-----SWAAAVEAVIPMEDVQLDTLV 1011
Query 982 DDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNS 1027
+ + D +E T VEV +E + V EV S
Sbjct 1012 AEIDVSEPADDVAEQASTEE----VEVPSACVLEASQVANAAEVES 1053
Score = 138 bits (348), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 66/158 (42%), Positives = 102/158 (65%), Gaps = 0/158 (0%)
Query 1031 YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDY 1090
++ L ++V + D + A+ + ++VNAAN +LKHGGG+A A+++A+ +Q ESDDY
Sbjct 1192 HIVLNNDVTLVFGDAIAVARATEDCILVNAANTHLKHGGGIAAAIDRASGGLVQAESDDY 1251
Query 1091 IATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ GPL VG S +L GH LA LHVVGP+ +DIQLLK Y+ FN++ ++++PL+S
Sbjct 1252 VNFYGPLNVGDSTLLKGHGLATGILHVVGPDARANQDIQLLKRCYKAFNKYPLVVSPLIS 1311
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS 1188
AGIF +P SL + V T Y+ V + +Y+ L +
Sbjct 1312 AGIFCVEPRVSLEYLLSVVHTKTYVVVNSEKVYNDLAA 1349
>sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=1a PE=3 SV=1
Length=4383
Score = 1872 bits (4849), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1073/2886 (37%), Positives = 1630/2886 (56%), Gaps = 125/2886 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + +G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGENFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + I D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTI--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVD 2101
D K E+ I L K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAK-------ESKEINIIKLSGVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLT 2080
Query 2102 NSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNIV 2157
++ N+LS + + T+ G+ V S+P D + KP N VV N +
Sbjct 2081 GCRYVVRTANDLSMAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNKI 2138
Query 2158 TRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNY 2217
+ C N ++ + F LL + K T +A + + +F
Sbjct 2139 SACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFLT 2189
Query 2218 LKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTN 2275
K ++ II I+ L + ++I+S L +G G ++ ST
Sbjct 2190 FKWSVVARGACIIATIFLLWFNFIYANVIFSDFYL----PKIGFLPTFVGKIAQWIKSTF 2245
Query 2276 --VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAF 2321
VTI YC GSI C CL+G D LD Y +++ +Q ++ D AF
Sbjct 2246 SLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRAF 2300
Query 2322 -------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLV 2372
+V E ++Y L+T +FY L +Q+ ++ F+ ++ W + L+++L
Sbjct 2301 VDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLA 2360
Query 2373 QMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRR 2432
M P +R YI ASF ++ + HV GC+ C+ CYKRNR+ RV+C+TIV G+ R
Sbjct 2361 NMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIR 2420
Query 2433 SFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVD 2492
+ V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2421 YYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVT 2480
Query 2493 SVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES 2552
V + L++++ GQ+TY+ + S FV+ NL + KG ++V+V + + +++
Sbjct 2481 DVKQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVENDA--DKA 2538
Query 2553 SAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTL 2612
+ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L L
Sbjct 2539 NFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNAL 2598
Query 2613 VATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCN 2671
+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SCN
Sbjct 2599 IATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCN 2658
Query 2672 NYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRS 2731
N + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2659 NLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKK 2718
Query 2732 AAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLIT 2791
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2719 ACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFLLSLV-CFIG--LWCLM 2775
Query 2792 PVHVMSKHTDFSSEI-IGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTND 2848
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2776 PTYTVHK-SDFQLPVYTSYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSNS 2834
Query 2849 KACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDF 2908
ACP++ AV+ +++G V +P +LR LHF+ SA G CYTP I Y++F
Sbjct 2835 MACPIVVAVVDQDLGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSNF 2893
Query 2909 ATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPNT 2967
S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2894 YASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGFIRFPEV 2953
Query 2968 YLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLL 3027
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L+
Sbjct 2954 LREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDLI 3013
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
+F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ +V N +++ +
Sbjct 3014 YQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWCV 3073
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIIC 3147
+F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3074 NFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYISV 3133
Query 3148 ISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRY 3207
+ + H +W F+ RR+ + S TFEE AL TF++ K+ Y KL++ L +NRY
Sbjct 3134 VVSNHAFWVFA--YCRRLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNRY 3189
Query 3208 LALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSGF 3266
L+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3190 LSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSGI 3249
Query 3267 RKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSN 3326
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R ++
Sbjct 3250 VKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVTS 3309
Query 3327 HNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPS 3386
+F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3310 SDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKPQ 3369
Query 3387 GVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYG 3446
G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+FYG
Sbjct 3370 GAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGDFYG 3429
Query 3447 PFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLT 3506
P+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3430 PYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQVK 3489
Query 3507 QDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGV 3566
D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q +G+
Sbjct 3490 SDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAGI 3546
Query 3567 TFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAM 3626
QS R +KG W++ + ++ +W++F ++ N L + + + AM
Sbjct 3547 KLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAM 3605
Query 3627 MFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMY 3685
+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3606 LLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIY 3664
Query 3686 ASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNY 3744
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y
Sbjct 3665 GMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTY 3722
Query 3745 SGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYF 3804
+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N F
Sbjct 3723 TWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLF 3781
Query 3805 RLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSD 3864
R+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++D
Sbjct 3782 RMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLTD 3841
Query 3865 VKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGA 3924
VKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL + A
Sbjct 3842 VKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPAA 3901
Query 3925 VD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVL 3977
VD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + + L
Sbjct 3902 VDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQL 3961
Query 3978 KKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTML 4037
K+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+
Sbjct 3962 KQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMV 4021
Query 4038 RKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWE 4097
RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W+
Sbjct 4022 RKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQ 4081
Query 4098 IQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCA 4155
IQ + D+D QL+EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4082 IQTIQDSDGTNKQLNEISDDCN----WPLVIIANRHNEVSATVLQNNELMPAKLKTQVVN 4137
Query 4156 AGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRF 4215
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4138 SGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCKF 4194
Query 4216 VTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVD 4275
KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+VD
Sbjct 4195 TVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSVD 4254
Query 4276 AAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHID 4335
K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+YCR ++
Sbjct 4255 PKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIYCRARVE 4314
Query 4336 HPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSAD 4395
HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS D
Sbjct 4315 HPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSKD 4372
Query 4396 AQSFLN 4401
+FLN
Sbjct 4373 T-NFLN 4377
Score = 83.2 bits (204), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 79/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFD 1425
Score = 76.3 bits (186), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 207/933 (22%), Positives = 355/933 (38%), Gaps = 164/933 (18%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E S+ L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSLDSLS-AAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F+++ I ++ S V +
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKN---IPRYASA-----VAQAFRS 709
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK + +S++ F + I + G+K+ + G + HS L +
Sbjct 710 VAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP KA ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A +VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRRVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVVDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDE 931
+ + +LFDE+GE LAS +YC+F P++D+
Sbjct 936 KLEDNSLFLFDEAGEEVLASKLYCAFTAPEDDD 968
>sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=1a PE=3 SV=1
Length=4383
Score = 1871 bits (4847), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1073/2886 (37%), Positives = 1631/2886 (57%), Gaps = 125/2886 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E +P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYNPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + I D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTI--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVD 2101
D K E+ I L K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAK-------ESKEINIIKLSGVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLT 2080
Query 2102 NSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNIV 2157
++ N LS + + T+ G+ V S+P D + KP N VV N +
Sbjct 2081 GCRYVVRTANALSMAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNKI 2138
Query 2158 TRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNY 2217
+ C N ++ + F LL + K T +A + + +F
Sbjct 2139 SACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFLT 2189
Query 2218 LKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTN 2275
K ++ II I+ L + ++I+S L +G G ++ ST
Sbjct 2190 FKWSVVARGACIIATIFLLWFNFIYANVIFSDFYL----PKIGFLPTFVGKIAQWIKSTF 2245
Query 2276 --VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAF 2321
VTI YC GSI C CL+G D LD Y +++ +Q ++ D AF
Sbjct 2246 SLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRAF 2300
Query 2322 -------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLV 2372
+V E ++Y L+T +FY L +Q+ ++ F+ ++ W + L+++L
Sbjct 2301 VDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLA 2360
Query 2373 QMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRR 2432
M P +R YI ASF ++ + HV GC+ C+ CYKRNR+ RV+C+TIV G+ R
Sbjct 2361 NMLPAHVFMRFYIIIASFIKLFILFRHVAYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIR 2420
Query 2433 SFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVD 2492
+ V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2421 YYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVT 2480
Query 2493 SVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES 2552
V + L++++ GQ+TY+ + S FV+ NL + KG ++V+V + + +++
Sbjct 2481 DVKQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVENDA--DKA 2538
Query 2553 SAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTL 2612
+ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L L
Sbjct 2539 NFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNAL 2598
Query 2613 VATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCN 2671
+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SCN
Sbjct 2599 IATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCN 2658
Query 2672 NYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRS 2731
N + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2659 NLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKK 2718
Query 2732 AAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLIT 2791
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2719 ACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFLLSLV-CFIG--LWCLM 2775
Query 2792 PVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTND 2848
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2776 PTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSNS 2834
Query 2849 KACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDF 2908
ACP++ AV+ +++G V +P +LR LHF+ SA G CYTP I Y++F
Sbjct 2835 MACPIVVAVVDQDLGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSNF 2893
Query 2909 ATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPNT 2967
S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2894 YASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGFIRFPEV 2953
Query 2968 YLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLL 3027
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L+
Sbjct 2954 LREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDLI 3013
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
+F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ +V N +++ +
Sbjct 3014 YQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWCV 3073
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIIC 3147
+F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3074 NFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYISV 3133
Query 3148 ISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRY 3207
+ + H +W F+ RR+ + S TFEE AL TF++ K+ Y KL++ L +NRY
Sbjct 3134 VVSNHAFWVFA--YCRRLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNRY 3189
Query 3208 LALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSGF 3266
L+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3190 LSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSGI 3249
Query 3267 RKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSN 3326
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R ++
Sbjct 3250 VKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVTS 3309
Query 3327 HNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPS 3386
+F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3310 SDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKPQ 3369
Query 3387 GVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYG 3446
G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+FYG
Sbjct 3370 GAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGDFYG 3429
Query 3447 PFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLT 3506
P+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3430 PYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQVK 3489
Query 3507 QDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGV 3566
D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q +G+
Sbjct 3490 SDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAGI 3546
Query 3567 TFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAM 3626
QS R +KG W++ + ++ +W++F ++ N L + + + AM
Sbjct 3547 KLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAM 3605
Query 3627 MFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMY 3685
+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3606 LLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIY 3664
Query 3686 ASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNY 3744
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y
Sbjct 3665 GMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTY 3722
Query 3745 SGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYF 3804
+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N F
Sbjct 3723 TWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLF 3781
Query 3805 RLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSD 3864
R+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++D
Sbjct 3782 RMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLTD 3841
Query 3865 VKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGA 3924
VKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL + A
Sbjct 3842 VKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPAA 3901
Query 3925 VD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVL 3977
VD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + + L
Sbjct 3902 VDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQL 3961
Query 3978 KKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTML 4037
K+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+
Sbjct 3962 KQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMV 4021
Query 4038 RKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWE 4097
RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W+
Sbjct 4022 RKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQ 4081
Query 4098 IQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCA 4155
IQ + D+D QL+EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4082 IQTIQDSDGTNKQLNEISDDCN----WPLVIIANRHNEVSATVLQNNELMPAKLKTQVVN 4137
Query 4156 AGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRF 4215
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4138 SGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCKF 4194
Query 4216 VTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVD 4275
KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+VD
Sbjct 4195 TVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSVD 4254
Query 4276 AAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHID 4335
K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+YCR ++
Sbjct 4255 PKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIYCRARVE 4314
Query 4336 HPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSAD 4395
HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS D
Sbjct 4315 HPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSKD 4372
Query 4396 AQSFLN 4401
+FLN
Sbjct 4373 T-NFLN 4377
Score = 83.2 bits (204), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 79/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFD 1425
Score = 75.9 bits (185), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 207/933 (22%), Positives = 355/933 (38%), Gaps = 164/933 (18%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E S+ L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSLDSLS-AAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F+++ I ++ S V +
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKN---IPRYASA-----VAQAFRS 709
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK + +S++ F + I + G+K+ + G + HS L +
Sbjct 710 VAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP KA ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A +VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRRVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDE 931
+ + +LFDE+GE LAS +YC+F P++D+
Sbjct 936 KLEDNSLFLFDEAGEEVLASKLYCAFTAPEDDD 968
>sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus
OC43 OX=31631 GN=1a PE=1 SV=1
Length=4383
Score = 1860 bits (4819), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1076/2890 (37%), Positives = 1628/2890 (56%), Gaps = 133/2890 (5%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCFKWQVVVNGKYFTFKQANNNCFVNVSCLMLQSLH 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
L F Q+A+ R+G A F AL+LA G+ D R+ + +F +L
Sbjct 1685 LTFKIVQWQEAWLEFRSGRPARFVALVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q G++AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGLDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFIGD-NVGHYVHVKCEQSYQLYDASNVKKVTDVTGKLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + + D LN G+ E K+T +P GDVV + Y +++G
Sbjct 1920 YTNFKLIGHTV--CDSLNSKLGFDSSKEFVEYKITEWPTATGDVVLANDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D + +
Sbjct 1978 ITFGKPVIWLSHEKASLNSLTY----------FNRPLLVDDNKFDVLKVDDVDDSGDSSE 2027
Query 2042 EDLKPVSE-EVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
K E +++ ++K +V +I+ + K + + D+ ++
Sbjct 2028 SGAKETKEINIIKLSGVKKPF--------KVEDSVIVNDDTSETKYVKSLSIVDVYDMWL 2079
Query 2101 DNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNI 2156
++ N LSR + + T+ G+ V S+P D + KP +N VV N
Sbjct 2080 TGCKYVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPAVN-VVKAVRNK 2137
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
+ C N ++ + F LL + K T IA + + +F
Sbjct 2138 TSACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEIASKLTCKLVALAFKNAFL 2188
Query 2217 YLKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLG-MPSYCTGYREGYLNS 2273
K ++ II I+ L + ++I+S L +G +P++ + N+
Sbjct 2189 TFKWSMVARGACIIATIFLLWFNFIYANVIFSDFYL----PKIGFLPTFVGKIAQWIKNT 2244
Query 2274 TN-VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTA 2320
+ VTI YC GSI C CL+G D LD Y +++ +Q ++ D A
Sbjct 2245 FSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRA 2299
Query 2321 F-------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINL 2371
F +V E ++Y L+T +FY L +Q+ ++ F+ ++ W L++ L
Sbjct 2300 FVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSFRLLVAL 2359
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
M P +R YI ASF ++ + HV GC+ S C+ CYKRNR+ RV+C+TIV G+
Sbjct 2360 ANMLPAHVFMRFYIIIASFIKLFSLFKHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMI 2419
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2420 RYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTV 2479
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEE 2551
V S+ L++D+ GQ+ Y+ + S FV+ NL + K ++V+V + + ++
Sbjct 2480 TDVKQVGCSMRLFYDRDGQRIYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DK 2537
Query 2552 SSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKT 2611
++ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L
Sbjct 2538 ANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNA 2597
Query 2612 LVATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSC 2670
L+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SC
Sbjct 2598 LIATAHSSIKQGTQIYKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESC 2657
Query 2671 NNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIR 2730
NN + TY K +N+ DLG I SA+H+ VAK ++ IW+V F S + +++
Sbjct 2658 NNLVPTYLKSDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQFSSDFQHKLK 2717
Query 2731 SAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLI 2790
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2718 KACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLV-CFIG--LWCL 2774
Query 2791 TPVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTN 2847
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2775 MPTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2848 DKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTD 2907
ACP++ AVI ++ G V +P +LR LHF+ SA G CYTP I Y++
Sbjct 2834 SMACPIVVAVIDQDFGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2908 FATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPN 2966
F S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2893 FYASGCVLSSACTMFTMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRFPE 2952
Query 2967 TYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNL 3026
EG VRVV T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L
Sbjct 2953 VLREGLVRVVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3027 LTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL 3086
+ +F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ VV N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSVVFVNVIVWC 3072
Query 3087 MSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYII 3146
++F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIA 3132
Query 3147 CISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ + H +W FS R++ + S TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVFS--YCRKLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSG 3265
YL+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3266 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKS 3325
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3326 NHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSP 3385
+ +F V + L V+ + M+ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMRGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3386 SGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFY 3445
G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3446 GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3505
GP+ D Q Q D +VN LAWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPIQDYIQSVNFLAWLYAAILNNCNWFIQSDKCSVEDFNVWALSNGFSQV 3488
Query 3506 TQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSG 3565
D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3566 VTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFA 3625
+ QS R KGT W++ + ++ +W++F ++ N F + + + A
Sbjct 3546 IKLQSKRTRLFKGTVCWIMASTFLFSCIITAFVKWTMFMYVTTNMF-SITFCALCVISLA 3604
Query 3626 MMFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
M+ VKHKH +L +++ P L T+ Y N +V ++ + WL S+ + D V+
Sbjct 3605 MLLVKHKHLYLTMYITPVLFTLLYNNYLVVYKHTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3685 YASAVVL-LILMTARTVYDD---GARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISV 3740
Y +++ ++ +T R++ D V L++V +L YK G+ L++ I + ++ S+
Sbjct 3664 YGMLLLVGMVFVTLRSINHDLFSFIMFVGRLISVFSLWYK---GSNLEEEILL--MLASL 3718
Query 3741 TSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLL 3800
Y+ M +A+ ++ V ++F ++ ++L Y F+GY +CY+GLF L+
Sbjct 3719 FGTYTWTTVLSMAVAK-VIAKWVAVNVLYFTDIPQIKIVLLCYLFIGYIISCYWGLFSLM 3777
Query 3801 NRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQS 3860
N FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QS
Sbjct 3778 NSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQS 3837
Query 3861 KMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLS 3920
K++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D + AFEK+ LL VL +
Sbjct 3838 KLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFEKLAQLLIVLFA 3897
Query 3921 MQGAVD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS- 3973
AVD I ++C++ + LQA+ SEF ++ S+ + A++ ++A +G +
Sbjct 3898 NPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARFSGSAN 3957
Query 3974 EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTML 4033
+ LK+L+K+ N+AKS ++RD A+ +KLE+MAD A+T MYK+AR DK++KV SA+QTML
Sbjct 3958 QQQLKQLEKACNIAKSAYERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTML 4017
Query 4034 FTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYAS 4093
F+M+RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA
Sbjct 4018 FSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTYAG 4077
Query 4094 ALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQ 4151
+W+IQ + D+D QL+EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4078 NVWQIQTIQDSDGTNKQLNEISDDCN----WPLVIIANRYNEVSATVLQNNELMPAKLKI 4133
Query 4152 MSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEP 4211
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+P
Sbjct 4134 QVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDP 4190
Query 4212 PCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCA 4271
PC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CA
Sbjct 4191 PCKFTVQDAKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCA 4250
Query 4272 FAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCR 4331
F+VD K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR
Sbjct 4251 FSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCR 4310
Query 4332 CHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPML 4391
++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +
Sbjct 4311 ARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCRVCGFWRDGSCSCVS-TDTTV 4368
Query 4392 QSADAQSFLN 4401
QS D +FLN
Sbjct 4369 QSKDT-NFLN 4377
Score = 80.9 bits (198), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 79/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K VK VVVN AN ++ HGGGVA A+ A E+ + + +
Sbjct 1273 ITPNVCFVKGDIIKVSKLVKAEVVVNPANGHMVHGGGVAKAIAVAAGQQFVKETTNMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++FN ++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYVLLERVYKHFNNYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T + V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFD 1425
Score = 63.5 bits (153), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 63/242 (26%), Positives = 103/242 (43%), Gaps = 30/242 (12%)
Query 715 GLYRKCVKSRE----ETGLL----MPL------------KAPKEIIFLEGETLPTEVLTE 754
G R C+ R+ E GLL +PL KA ++ I+L+G +
Sbjct 732 GRRRICLSGRKIYEVERGLLHSSQLPLDVYDLTMPSQVQKAKQKPIYLKGSGSDFSLADS 791
Query 755 EVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFT 814
V + T L P E P V +CI + + + Y + + + +
Sbjct 792 VVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDDHVGLLDQAW 846
Query 815 LKGGAPTKVTFGDD-TVIEVQGY-KSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFA 872
A +VTF + TV E+ K + + +ELD + +LN C + V+ ++ EF
Sbjct 847 RVPCAGRRVTFKEQPTVKEIISMPKIIKVFYELDNDFNTILNTACGVFEVDDTVDMEEFY 906
Query 873 CVVADAVIKTLQPVSELL---TPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDE 929
VV DA+ + L P EL + L + +LFDE+GE A +YC+F P++
Sbjct 907 AVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNPLFLFDEAGEEVFAPKLYCAFTAPED 966
Query 930 DE 931
D+
Sbjct 967 DD 968
>sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=1a PE=3 SV=1
Length=4383
Score = 1859 bits (4815), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1067/2887 (37%), Positives = 1628/2887 (56%), Gaps = 127/2887 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + + D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTV--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLK-PVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
D K P +++ ++K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAKEPKEINIIKLSGVKKPF--------KVEDSVIVNDDTSEIKYVKSLSIVDVYDMWL 2079
Query 2101 DNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNI 2156
++ N LSR + + T+ G+ V S+P D + KP N VV N
Sbjct 2080 TGCRCVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNK 2137
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
++ C N ++ + F LL + K T +A + + +F
Sbjct 2138 ISACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFL 2188
Query 2217 YLKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLG-MPSYCTGYREGYLNS 2273
K ++ II I+ L + ++I+S L +G +P++ + N+
Sbjct 2189 TFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYL----PKIGFLPTFVGKIAQWIKNT 2244
Query 2274 TN-VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTA 2320
+ VTI YC GSI C CL+G D LD Y +++ +Q ++ D A
Sbjct 2245 FSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRA 2299
Query 2321 F-------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINL 2371
F +V E ++Y L+T +FY L +Q+ ++ F+ ++ W + L+++L
Sbjct 2300 FVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSL 2359
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
M P +R YI ASF ++ + HV GC+ S C+ CYKRNR+ RV+C+TIV G+
Sbjct 2360 ANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMI 2419
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R + ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2420 RYYDAMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTV 2479
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEE 2551
V + L++D+ GQ+TY+ + S FV+ NL + K ++V+V + + ++
Sbjct 2480 TDVKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DK 2537
Query 2552 SSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKT 2611
++ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L
Sbjct 2538 ANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNA 2597
Query 2612 LVATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSC 2670
L+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SC
Sbjct 2598 LIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESC 2657
Query 2671 NNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIR 2730
NN + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2658 NNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLK 2717
Query 2731 SAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLI 2790
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2718 KACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLV-CFIG--LWCL 2774
Query 2791 TPVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTN 2847
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2775 MPTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2848 DKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTD 2907
ACP++ AV+ ++ G V +P +LR LHF+ SA G CYTP I Y++
Sbjct 2834 SMACPIVVAVVDQDFGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2908 FATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPN 2966
F S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2893 FYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRFPE 2952
Query 2967 TYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNL 3026
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L
Sbjct 2953 VLREGLVRIVRTRSMPYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3027 LTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL 3086
+ +F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ +V N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWC 3072
Query 3087 MSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYII 3146
++F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIS 3132
Query 3147 CISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ + H +W FS R++ + S TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVFS--YCRQLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSG 3265
YL+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3266 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKS 3325
KM P+ KVE C+V VT G TLNGLWL D VYCPRHVIC++ DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCIVSVTYGNMTLNGLWLGDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3326 NHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSP 3385
+ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3386 SGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFY 3445
G + MR ++TIKGSFL GSCGSV + I DCV F YMH +EL TG H GTD G+FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVVYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3446 GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3505
GP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQV 3488
Query 3506 TQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSG 3565
D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKH-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3566 VTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFA 3625
+ QS R +KG W++ + ++ +W++F ++ N L + + +
Sbjct 3546 IKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLT 3604
Query 3626 MMFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
M+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+
Sbjct 3605 MLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3685 YASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSN 3743
Y +++ ++ +T R++ + + V+++V Y G+ L++ I + ++ S+
Sbjct 3664 YGMLLLIGMVFVTLRSINQYLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGT 3721
Query 3744 YSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
Y+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N
Sbjct 3722 YTWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSL 3780
Query 3804 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMS 3863
FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++
Sbjct 3781 FRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLT 3840
Query 3864 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3923
DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL +
Sbjct 3841 DVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPA 3900
Query 3924 AVD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVV 3976
AVD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + +
Sbjct 3901 AVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQ 3960
Query 3977 LKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTM 4036
LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M
Sbjct 3961 LKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSM 4020
Query 4037 LRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALW 4096
+RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W
Sbjct 4021 VRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVW 4080
Query 4097 EIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSC 4154
+IQ + D+D QL EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4081 QIQTIQDSDGTNKQLHEISDDCN----WPLVIIANRHNEVSATALQNNELMPAKLKTQVV 4136
Query 4155 AAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCR 4214
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+
Sbjct 4137 NSGPDQTCNTPTQ--CYYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCK 4193
Query 4215 FVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAV 4274
F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+V
Sbjct 4194 FTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSV 4253
Query 4275 DAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHI 4334
D K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR +
Sbjct 4254 DPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCRARV 4313
Query 4335 DHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA 4394
+HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS
Sbjct 4314 EHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSK 4371
Query 4395 DAQSFLN 4401
D +FLN
Sbjct 4372 DT-NFLN 4377
Score = 84.3 bits (207), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T + V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFD 1425
Score = 71.2 bits (173), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 224/1007 (22%), Positives = 373/1007 (37%), Gaps = 179/1007 (18%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYAGKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E S+ L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSLDSL-GAAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F+++ I ++ S V +
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKN---IPRYASA-----VAQAFRS 709
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK + +S++ F + I + G+K+ + G + HS L +
Sbjct 710 VAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP K ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKTKQKPIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRCVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTED---DY 955
+ + +LFDE+GE LA +YC+F P++D D EE E D
Sbjct 936 KLEDNSLFLFDEAGEEVLAPKLYCAFTAPEDD----DFLEESGVEEDDVEGEETDLTVTS 991
Query 956 QGKPLEFGATSAALQPEEEQE--EDWLDDDSQQTVGQQDGSEDNQTT 1000
G+P A + EE E ED LDD ED Q +
Sbjct 992 AGEP------CVASEQEESSEILEDTLDDGPCVETSDSQVEEDVQMS 1032
>sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=1a PE=3 SV=1
Length=4383
Score = 1858 bits (4812), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1066/2887 (37%), Positives = 1626/2887 (56%), Gaps = 127/2887 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + + D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTV--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLK-PVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
D K P +++ ++K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAKEPKEINIIKLSGVKKPF--------KVEDSVIVNDDTSEIKYVKSLSIVDVYDMWL 2079
Query 2101 DNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNI 2156
++ N LSR + + T+ G+ V S+P D + KP N VV N
Sbjct 2080 TGCRCVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNK 2137
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
++ C N ++ + F LL + K T +A + + +F
Sbjct 2138 ISACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFL 2188
Query 2217 YLKSPNFSKLINII--IWFLLLSVCLGSLIYS---TAALGVLMSNLG-----------MP 2260
K ++ II I+ L + ++I+S +G L + +G +
Sbjct 2189 TFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIVQWIKNTFSLV 2248
Query 2261 SYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTA 2320
+ C Y + N YC GSI C CL+G D LD Y +++ +Q ++ D A
Sbjct 2249 TICDLYSIQDVGFKN----QYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRA 2299
Query 2321 F-------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINL 2371
F +V E ++Y L+T +FY L +Q+ ++ + ++ W + L+++L
Sbjct 2300 FVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELLMLSTLHWSVRLLVSL 2359
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
M P +R YI ASF ++ + HV GC+ S C+ CYKRNR+ RV+C+TIV G+
Sbjct 2360 ANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMI 2419
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2420 RYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTV 2479
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEE 2551
V + L++D+ GQ+TY+ + S FV+ NL + K ++V+V + + ++
Sbjct 2480 TDVKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DK 2537
Query 2552 SSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKT 2611
++ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L
Sbjct 2538 ANFLNAAVFYAQSLFRPILMVDKILITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNA 2597
Query 2612 LVATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSC 2670
L+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SC
Sbjct 2598 LIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESC 2657
Query 2671 NNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIR 2730
NN + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2658 NNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLK 2717
Query 2731 SAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLI 2790
A K L +LT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2718 KACCKTGLKLELTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLV-CFIG--LWCL 2774
Query 2791 TPVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTN 2847
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2775 MPTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2848 DKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTD 2907
ACP++ AV+ ++ G V +P +LR LHF+ SA G CYTP I Y++
Sbjct 2834 SMACPIVVAVVDQDFGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2908 FATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPN 2966
F S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+ P
Sbjct 2893 FYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRLPE 2952
Query 2967 TYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNL 3026
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L
Sbjct 2953 VLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3027 LTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL 3086
+ +F L QP+ L ++AS +AG I+A++V YY ++ +RAFG+Y+ +V N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLGFYYLIKLKRAFGDYTSIVFVNVIVWC 3072
Query 3087 MSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYII 3146
++F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIS 3132
Query 3147 CISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ + H +W FS R++ + S TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVFS--YCRQLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSG 3265
YL+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3266 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKS 3325
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3326 NHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSP 3385
+ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3386 SGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFY 3445
G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3446 GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3505
GP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQV 3488
Query 3506 TQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSG 3565
D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3566 VTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFA 3625
+ QS R +KG W++ + ++ +W++F ++ N L + + + A
Sbjct 3546 IKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLA 3604
Query 3626 MMFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
M+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+
Sbjct 3605 MLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3685 YASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSN 3743
Y +++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+
Sbjct 3664 YGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGT 3721
Query 3744 YSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
Y+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N
Sbjct 3722 YTWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSL 3780
Query 3804 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMS 3863
FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++
Sbjct 3781 FRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLT 3840
Query 3864 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3923
DVKC + LL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL +
Sbjct 3841 DVKCANGGLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPA 3900
Query 3924 AVD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVV 3976
AVD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + +
Sbjct 3901 AVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQ 3960
Query 3977 LKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTM 4036
LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M
Sbjct 3961 LKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSM 4020
Query 4037 LRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALW 4096
+RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W
Sbjct 4021 VRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVW 4080
Query 4097 EIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSC 4154
+IQ + D+D QL EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4081 QIQTIQDSDGTNKQLHEISDDCN----WPLVIIANRHNEVSATVLQNNELMPAKLKTQVV 4136
Query 4155 AAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCR 4214
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+
Sbjct 4137 NSGPDQTCNTPTQ--CYYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCK 4193
Query 4215 FVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAV 4274
F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+V
Sbjct 4194 FTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSV 4253
Query 4275 DAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHI 4334
D K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR +
Sbjct 4254 DPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCRARV 4313
Query 4335 DHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA 4394
+HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS
Sbjct 4314 EHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSK 4371
Query 4395 DAQSFLN 4401
D +FLN
Sbjct 4372 DT-NFLN 4377
Score = 84.3 bits (207), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T + V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFD 1425
Score = 63.2 bits (152), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 51/172 (30%), Positives = 76/172 (44%), Gaps = 18/172 (10%)
Query 837 KSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPL 893
K++ + +ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL +
Sbjct 871 KTIKVFYELDKDFNTILNTACGEFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKV 930
Query 894 GIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTED 953
L + + +LFDE+GE LA +YC+F P++D D EE E D
Sbjct 931 SAFLQKLEDNSLFLFDEAGEEVLAPKLYCAFTAPEDD----DFLEESGVEEDDVEGEETD 986
Query 954 ---DYQGKPLEFGATSAALQPEEEQE--EDWLDDDSQQTVGQQDGSEDNQTT 1000
G+P A + EE E ED LDD ED Q +
Sbjct 987 LTVTSAGEP------CVASEQEESSEILEDTLDDGPCVETSDSQVEEDVQMS 1032
>sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus
(strain 2) OX=76344 GN=1a PE=3 SV=1
Length=4416
Score = 1834 bits (4751), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1084/2925 (37%), Positives = 1610/2925 (55%), Gaps = 163/2925 (6%)
Query 1549 EVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIK 1608
+V + ++ LL+ + V TVD +N + V +G+ G + DG +VTK++
Sbjct 1543 KVASVSQIRALLA----NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVR 1598
Query 1609 PHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIK 1668
H+GK F+ + A D L +Y + L K W + K
Sbjct 1599 CSAIHKGKVFFQYSGLSAADLVAVTDAFGFDEPQLLKYYNMLGMCK-WPVVVCGNYFAFK 1657
Query 1669 WADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDV 1728
++NNCY+ A L LQ + LKF+ Q+A+ R+G+ F +L+LA + E D
Sbjct 1658 QSNNNCYINVACLMLQHLSLKFHKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDS 1717
Query 1729 RETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCT 1788
+ M + + A+L VCK CG +Q KGV+AVM+ GTL KG I CT
Sbjct 1718 TDFMRVVLREADLSGATCDFEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLAKGYTIACT 1776
Query 1789 CGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCI 1848
CG + + Q PF++ S P +L A+ +TG GHY H+ K
Sbjct 1777 CGNKLV-HCTQLNVPFLICSNKPEGKKLPDDVVA-ANIFTGG-SLGHYTHVKCKPKYQLY 1833
Query 1849 DGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYF 1907
D ++K SE KG TD Y +N T + K T+ LD V C E +P L YY + Y+
Sbjct 1834 DACNVSKVSEAKGNFTDCLYLKNLKQTFSSKLTTFYLDDVKCVEYNPDLSQYYCESGKYY 1893
Query 1908 TEQPIDLVPNQPYPNAS--FDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLN 1964
T +PI + + + NFK V +I A+ N G+ E K+T +P
Sbjct 1894 T-KPIIKAQFRTFEKVEGVYTNFKLVGHSI--AEKFNAKLGFDCNSPFTEYKITEWPTAT 1950
Query 1965 GDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVE 2020
GDVV Y + G KP++W H + TY +P+ C ++ PV+
Sbjct 1951 GDVVLASDDLYVSRYSGGCVTFGKPVIWLGHEEASLKSLTYFNRPSVVC-ENKFNVLPVD 2009
Query 2021 TSNSFD-------VLKSEDAQG---MDNLACEDLKPVSEEVVEN---------PTIQKDV 2061
S D VL + G A E S+ VV+ DV
Sbjct 2010 VSEPTDKGPVPAAVLVTGALSGAATAPGTAKEQKVCASDSVVDQVVSGFLSDLSGATVDV 2069
Query 2062 LECNV----KTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVL 2117
E + K +V +++ + K+ + + D+ ++ + NELSR+
Sbjct 2070 KEVKLNGVKKPIKVEDSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWMANELSRL- 2128
Query 2118 GLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNR-------------V 2164
VNS T+ Y K + K+V ++ R +
Sbjct 2129 ------------VNS---PTVREYVKWGMTKIVIPAKLVLLRDEKQEFVAPKVVKAKVIA 2173
Query 2165 CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFS 2224
C + + +FF F N+ K T +A K C A N L++ N++
Sbjct 2174 CYSAVKWFFLYCFSWIKF----NTDNKVIYTTEVAS---KLTFNLCCLAFKNALQTFNWN 2226
Query 2225 KLIN--------IIIWF-------LLLSVCLGSLIYSTAALGVLMS----NLGMPSYCTG 2265
+ ++WF +L L ++ + +G +++ G+ + C
Sbjct 2227 VVSRGFFLVATVFLLWFNFLYANVILSDFYLPNIGFFPTFVGQIVAWVKTTFGIFTLCDL 2286
Query 2266 YR---EGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLT 2319
Y+ GY +S +C GS+ C +C SG D LD Y ++ +Q + SF + ++
Sbjct 2287 YQVSDVGYRSS-------FCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRVSFDY-IS 2338
Query 2320 AFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPI 2377
F LV E + Y L+T FY L MQL ++ F+ + W + + M P
Sbjct 2339 LFKLVVELVIGYSLYTVCFYPLFGLIGMQLLTTWLPEFFMLETMHWSARFFVFVANMLPA 2398
Query 2378 SAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVY 2437
++R YI + Y ++ HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V
Sbjct 2399 FTLLRFYIVVTAMYKIFCLCRHVMYGCSRPGCLFCYKRNRSVRVKCSTVVGGTLRYYDVM 2458
Query 2438 ANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVK 2497
ANGG GFC H WNC+NC F G+TFI+ E A DLS + KRP+NPTD + Y+V V
Sbjct 2459 ANGGTGFCAKHQWNCLNCSAFGPGNTFITHEAAADLSKELKRPVNPTDSAYYLVTEVKQV 2518
Query 2498 NGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSA 2557
S+ L++++ GQ+ Y+ S S FV+++ L + KG +V+V + ++ +++ +A
Sbjct 2519 GCSMRLFYERDGQRVYDDVSASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNA 2576
Query 2558 SVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAE 2617
+V+Y+Q + +P+LL+++ L++ V+ MFD YV++ +V + L + V A
Sbjct 2577 AVFYAQSLYRPMLLVEKKLITTANTGLSVSQTMFDLYVDSLLGVLDVDRKSLTSFVNAAH 2636
Query 2618 AELAKNVSLDNVLSTFISAARQG-FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLT 2676
L + V L+ V+ TFI AR+ +DSDVETK + + + + + ++ T +SCNN + T
Sbjct 2637 NSLKEGVQLEQVMDTFIGCARRKCAIDSDVETKSITKSIMSAVNAGVDFTDESCNNLVPT 2696
Query 2677 YNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKN 2736
Y K + + DLG I +A+H+ A VAK+ N+A IW+V F LS L+ ++R A K
Sbjct 2697 YVKSDTIVAADLGVLIQNNAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKT 2756
Query 2737 NLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVM 2796
L KLT V ++TT +LKGG + + L+ L V L+ V + + P + +
Sbjct 2757 GLKIKLTYNKQEANVPILTTPFSLKGGAVFSKVLQWLFVVNLICFIV---LWALMPTYAV 2813
Query 2797 SKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLI 2854
K +K ID GV RD+ TD CFANK FD W+ G Y N +ACP++
Sbjct 2814 HKSDMQLPLYASFKVIDNGVLRDVTVTDACFANKFIQFDQWYESTFGLVYYRNSRACPVV 2873
Query 2855 AAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACV 2914
AVI +++G+ + +P +LR LHF+ F+ CYTP I Y +F S CV
Sbjct 2874 VAVIDQDIGYTLFNVPTKVLR-YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCV 2932
Query 2915 LAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSV 2973
L++ CT+ A G P PYCY ++ + Y+SL P RY L + + I+FP EG V
Sbjct 2933 LSSLCTMLAHADGTPHPYCYTEGIMHNASLYDSLAPHVRYNLANSNGYIRFPEVVSEGIV 2992
Query 2974 RVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTP 3033
R+V T YCR G CE +E GVC + + WVLNN YYR++PG FCG +A +L+ +
Sbjct 2993 RIVRTRSMTYCRVGLCEDAEEGVCFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGG 3052
Query 3034 LIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLC 3093
L++PI ++AS VAG I+AI+V YY ++ +RAFG+Y+ VV N +++ ++F +L
Sbjct 3053 LVRPIDFFALTASSVAGAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLF 3112
Query 3094 LTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHF 3153
+ VY L +Y+ Y Y T Y +++S + H+QW+VM+ ++P W I Y+ + + H
Sbjct 3113 VFQVYPTLSCLYACFYFYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHA 3172
Query 3154 YWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNK 3213
W FS R++ S TFEE +L TF++ KE Y KL++ V +NRYL+LYNK
Sbjct 3173 LWLFS--YCRKLGTEVRSDGTFEEMSLTTFMITKESYCKLKNSV--SDVAFNRYLSLYNK 3228
Query 3214 YKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFP 3272
Y+YFSG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S+T++ LQSG KM FP
Sbjct 3229 YRYFSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVFP 3288
Query 3273 SGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQ 3332
+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R + +F V
Sbjct 3289 TSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYSNLLCRVISSDFCVM 3348
Query 3333 AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCA 3392
+G + L V+ + MQ +L L V NP TPKY F ++PG+TF+VLA YNG G +
Sbjct 3349 SGRMSLTVMSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGKSQGAFHVT 3408
Query 3393 MRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQ 3452
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+ D Q
Sbjct 3409 MRSSYTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQ 3468
Query 3453 TAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDI 3512
Q D T TVNV+AWLYAA++N WF+ + +L +FN+ AM + + D V
Sbjct 3469 VVQLPVQDYTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV-- 3526
Query 3513 LGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAV 3572
L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q +GV QS
Sbjct 3527 LDALASMTGVTVEQILAAIKRLY-SGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKR 3585
Query 3573 KRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHK 3632
R +KGT W+L + L ++ +W++F ++ + L + + +FAM+ VKHK
Sbjct 3586 TRVVKGTCCWILASTLLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLVKHK 3644
Query 3633 HAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL 3691
H +L +F++P L T+ Y N +V S+ WL ++ + D V+Y VVL
Sbjct 3645 HLYLTMFIMPVLCTLFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLY--GVVL 3701
Query 3692 LILM---TARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
L+ M T R++ D ++ + +++LV Y+G L++ + ++ + S+ Y+
Sbjct 3702 LVAMVFVTMRSINHDVFSVMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW-- 3757
Query 3749 TTVMFLARG-IVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
TT++ LA ++ + ++F ++ ++L Y +GY C CY+G+ LLN FR+
Sbjct 3758 TTMLSLATAKVIAKWLAVNVLYFTDVPQVKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMP 3817
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
LGVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC
Sbjct 3818 LGVYNYKISVQELRYMNANGLRPPRNSFEALVLNFKLLGIGGVPVIEVSQIQSRLTDVKC 3877
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD- 3926
+VVLL+ LQ L + SSSKLW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3878 VNVVLLNCLQHLHIASSSKLWQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDS 3937
Query 3927 -----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKL 3980
I ++ ++ + + LQA+ SEF ++ S+ + A++ ++A A+G + + +K+L
Sbjct 3938 KCLASIEEVSDDYVRDSTVLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQL 3997
Query 3981 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4040
+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKL
Sbjct 3998 EKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKL 4057
Query 4041 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQ 4100
DN ALN+I++NA GCVPLN IP T+ L +++PD + D TYA +W IQ
Sbjct 4058 DNQALNSILDNAVKGCVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQS 4117
Query 4101 VVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGT 4158
+ DAD + QL+EI + N+ WPL++ A R N S+V LQNNEL P LR +G+
Sbjct 4118 IQDADGAVKQLNEIDV----NITWPLVIAANRHNEVSSVVLQNNELMPQKLRTQVVNSGS 4173
Query 4159 TQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTD 4218
T YYNTT G+ V A+LSD LK+ + K DG + EL+PPC+F
Sbjct 4174 DMNCNTPTQ--CYYNTTGMGKIVYAILSDCDGLKYTKIVKEDGN-CVVLELDPPCKFSVQ 4230
Query 4219 TPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK 4278
KG K+KYLYF+KG N L RG V+G+L++TVRLQAG ATE +NS + S CAF+VD K
Sbjct 4231 DVKGLKIKYLYFVKGCNTLARGWVVGTLSSTVRLQAGTATEYASNSAIRSLCAFSVDPKK 4290
Query 4279 AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPN 4338
Y DY+ GG P+TNCVKMLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+
Sbjct 4291 TYLDYIQQGGAPVTNCVKMLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPD 4350
Query 4339 PKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSC 4383
G C L+GK+VQ+P DPV + L + VC VCG W+ CSC
Sbjct 4351 VDGLCKLRGKFVQVPLG-IKDPVSYVLTHDVCQVCGFWRDGSCSC 4394
Score = 72.0 bits (175), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 60/183 (33%), Positives = 83/183 (45%), Gaps = 21/183 (11%)
Query 819 APTKVTFGDD-TVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVAD 877
A KV F D V E+ + + I F LD D VL++ CS + V+ ++E VV D
Sbjct 832 AGKKVEFNDKPKVKEIPSTRKIKINFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLD 891
Query 878 AVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEG 934
AV TL P E + T + L+ + YLFDE GE +A MYCSF PD++
Sbjct 892 AVESTLSPCKEHDVIGTKVCALLNRLAEDYVYLFDEGGEEVIAPKMYCSFSAPDDE---- 947
Query 935 DCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGS 994
DC + + + + DD SAAL + QEED + Q V + D
Sbjct 948 DCVAADVVDADENQGDDADD-----------SAALV-TDTQEEDGV-AKGQVGVAESDAR 994
Query 995 EDN 997
D
Sbjct 995 LDQ 997
Score = 59.3 bits (142), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 52/154 (34%), Positives = 82/154 (53%), Gaps = 4/154 (3%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV D+++ ++V V+VN AN + HG GVAGA+ KA + E+ D +
Sbjct 1267 ITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKSFIKETADMVKN 1326
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENFNQHEVLLAPLLS 1150
G +VG +G NL K L++VGP+ +G Q L+ AY++ N+ + ++ L+S
Sbjct 1327 QGVCQVGECYESTGGNLCKTVLNIVGPDA-RGHGKQCYSFLERAYQHINKCDDVVTTLIS 1385
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
AGIF SL + V NV L +K+ +D
Sbjct 1386 AGIFSVPTDVSLTYLIGVVTKNVILVSNNKDDFD 1419
Score = 41.2 bits (95), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 84/343 (24%), Positives = 131/343 (38%), Gaps = 70/343 (20%)
Query 59 GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEI 114
GVLP+ +F + T HV +L + +G+ G +G +G VP V I
Sbjct 120 GVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCLG-NGRFIGWFVP-VTAI 177
Query 115 PVAYRK-------VLLRKNGNKG---AGGHSYGADLKSFDLGDELGTDPYEDFQENWNTK 164
P AY K +LLRK GNKG +G + +D E D E+ N K
Sbjct 178 P-AYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE---DACEEVHLNPKGK 233
Query 165 HSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDT 224
+S L++ G ++D C G + ++D CTL E +
Sbjct 234 YSRK-AYALLKGYRGVKSILFLDQYGCDYTGRLAKGLEDY------GDCTLEEMKELFP- 285
Query 225 KRGVYC-CREHEHEIAWYTERSEKS-YELQTPFEIKLAKKF-----DTFNGEC----PNF 273
V+C ++E +AW+ +R ++ LQT I+ D +G+ P
Sbjct 286 ---VWCDSLDNEVVVAWHVDRDPRAVMRLQTLATIRSIGYVGQPTEDLVDGDVVVREPAH 342
Query 274 VFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQT 333
+ N+I+K + PR+ + L Y +S E C T + CD T +
Sbjct 343 LLAANAIVKRL-PRLVETML----------YTDSSVTE---FCYKTKL-CDCGFITQFGY 387
Query 334 GDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNS 376
D C+F G++P N + CP C S
Sbjct 388 VDCCGDACDF-------------RGWVPGNMMDGFLCPGCSKS 417
>sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronavirus
(strain JHM) OX=11144 GN=1a PE=1 SV=1
Length=4474
Score = 1834 bits (4750), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1071/2905 (37%), Positives = 1597/2905 (55%), Gaps = 151/2905 (5%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ V TVD +N + V +G+ G + DG +VTK++ H+GK F+
Sbjct 1610 VDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIHKGKVFFQYSGLSAA 1669
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
+ A + D L +Y S L K W + K ++NNCY+ A L LQ +
Sbjct 1670 DLAAVKDAFGFDEPQLLQYYSMLGMCK-WPVVVCGNYFAFKQSNNNCYINVACLMLQHLS 1728
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF + R+G+ F +L+LA + E D + + + A+L
Sbjct 1729 LKFPKWQWRRPGNEFRSGKPLRFVSLVLAKGSFKFNEPSDSTDFIRVELREADLSGATCD 1788
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
L +CK CG +Q KGV+AVM+ GTL KG I CTCG + + Q PF++
Sbjct 1789 LEFICK-CGVKQEQRKGVDAVMHFGTLDKSGLVKGYNIACTCGDKLV-HCTQFNVPFLIC 1846
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S P +L A+ +TG GHY H+ K D ++K SE KG TD
Sbjct 1847 SNTPEGKKLPDDVVA-ANIFTGG-SVGHYTHVKCKPKYQLYDACNVSKVSEAKGNFTDCL 1904
Query 1868 YKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPNAS-- 1924
Y +N T + TY LD V C P L YY + Y+T +PI + +
Sbjct 1905 YLKNLKQTFSSVLTTYYLDDVKCVAYKPDLSQYYCESGKYYT-KPIIKAQFRTFEKVEGV 1963
Query 1925 FDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK V +I A+ LN G+ E K+T +P GDVV Y + G
Sbjct 1964 YTNFKLVGHDI--AEKLNAKLGFDCNSPFMEYKITEWPTATGDVVLASDDLYVSRYSGGC 2021
Query 1984 KLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVETSNSFD------------- 2026
KP++W H + TY +P+ C ++ PV+ S D
Sbjct 2022 VTFGKPVIWRGHEEASLKSLTYFNRPSVVC-ENKFNVLPVDVSEPTDRRPVPSAVLVTGA 2080
Query 2027 -------VLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVG------ 2073
+ +E + AC V +++V + V VK ++ G
Sbjct 2081 ASGADASAISTEPGTAKEQKACAS-DSVEDQIVMEAQKKSSVTTVAVKEVKLNGVKKPVK 2139
Query 2074 ---DIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATH---GL 2127
+++ + K+ + + D+ ++ + NELSR++ T+ + G+
Sbjct 2140 WNCSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWTANELSRLINSPTVREYVKWGM 2199
Query 2128 AAVNSVPWDTI--ANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRS 2185
+ + +P + + + + F+ V I C + +F F
Sbjct 2200 SKL-IIPANLLLLRDEKQEFVAPKVVKAKAIA-------CYGAVKWFLLYCFSWIKF--- 2248
Query 2186 TNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLIN--------IIIWF--LL 2235
N+ K T +A K K C A N L++ N+S + ++WF L
Sbjct 2249 -NTDNKVIYTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVFLLWFNFLY 2304
Query 2236 LSVCLGSL---------IYSTAALGVLMSNLGMPSYCTGYRE---GYLNSTNVTIATYCT 2283
+V L ++ + + + G+ + C Y+ GY +S +C
Sbjct 2305 ANVILSDFYLPNIGPLPMFVGQIVAWVKTTFGVLTICDFYQVTDLGYRSS-------FCN 2357
Query 2284 GSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
GS+ C +C SG D LD Y S+ +Q + SF + ++ F LV E + Y L+T FY
Sbjct 2358 GSMVCELCFSGFDMLDNYESINVVQHVVDRRVSFDY-ISLFKLVVELVIGYSLYTVCFYP 2416
Query 2341 LGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYV 2398
L + MQL ++ F+ + W L + + M P ++R YI + Y V+
Sbjct 2417 LFVLVGMQLLTTWLPEFFMLGTMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVYCLCR 2476
Query 2399 HVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTF 2458
HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC+NC+++
Sbjct 2477 HVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLNCNSW 2536
Query 2459 CAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSL 2518
G+TFI+ E A DLS + KRP+NPTD + Y V V S+ L++++ GQ+ Y+ S
Sbjct 2537 KPGNTFITHEAAADLSKELKRPVNPTDSAYYSVIEVKQVGCSMRLFYERDGQRVYDDVSA 2596
Query 2519 SHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVS 2578
S FV+++ L + KG +V+V + ++ +++ +A+V+Y+Q + +P+L++++ L++
Sbjct 2597 SLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRPMLMVEKKLIT 2654
Query 2579 DVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAAR 2638
V+ MFD YV + +V + L + V A L + V L+ V+ TF+ AR
Sbjct 2655 TANTGLSVSRTMFDLYVYSLLRHLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFVGCAR 2714
Query 2639 QG-FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSAR 2697
+ +DSDVETK + + + + + +EVT +SCNN + TY K + + DLG I +A+
Sbjct 2715 RKCAIDSDVETKSITKSVMAAVNAGVEVTDESCNNLVPTYVKSDTIVAADLGVLIQNNAK 2774
Query 2698 HINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTK 2757
H+ + VAK+ N+A IW+V F LS L+ ++R A K L KLT V ++TT
Sbjct 2775 HVQSNVAKAANVACIWSVDAFNQLSADLQHRLRKACVKTGLKIKLTYNKQEANVPILTTP 2834
Query 2758 IALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVT 2817
+LKGG + + L+ L L+ V + + P + + K +K ID GV
Sbjct 2835 FSLKGGAVFSRVLQWLFVANLICFIV---LWALMPTYAVHKSDMQLPLYASFKVIDNGVL 2891
Query 2818 RDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILR 2875
RD++ TD CFANK FD W+ G Y N KACP++ AVI +++G + +P +LR
Sbjct 2892 RDVSVTDACFANKFNQFDQWYESTFGLVYYRNSKACPVVVAVIDQDIGHTLFNVPTKVLR 2951
Query 2876 TTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYD 2935
LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P PYCY
Sbjct 2952 Y-GFHVLHFITHAFATDRVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHPYCYT 3010
Query 2936 TNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEA 2994
V+ + Y SL P RY L + I+FP EG VRVV T YCR G CE +E
Sbjct 3011 EGVMHNASLYSSLVPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLCEEAEE 3070
Query 2995 GVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVA 3054
G+C + + WVLNN YYR++PG FCG +A +L+ + L+QPI ++AS VAG I+A
Sbjct 3071 GICFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVQPIDFFALTASSVAGAILA 3130
Query 3055 IVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTF 3114
I+V YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L +Y+ Y Y T
Sbjct 3131 IIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFYTTL 3190
Query 3115 YLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFST 3174
Y +++S + H+QW+VM+ ++P W I Y+ + + H W FS R++ + S T
Sbjct 3191 YFPSEISVVMHLQWLVMYGAIMPLWFCITYVAVVVSNHALWLFS--YCRKIGTDVRSDGT 3248
Query 3175 FEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL 3234
FEE AL TF++ KE Y KL++ V +NRYL+LYNKY+YFSG MDT +YREAAC L
Sbjct 3249 FEEMALTTFMITKESYCKLKNSV--SDVAFNRYLSLYNKYRYFSGKMDTATYREAACSQL 3306
Query 3235 AKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
AKA+ F+ N+G+DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G TLNGL
Sbjct 3307 AKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCVVSVTYGNMTLNGL 3366
Query 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
WLDD VYCPRHVIC+S DM +P+Y +LL R ++ +F V + + L V+ + MQ +L L
Sbjct 3367 WLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSDRMSLTVMSYQMQGSLLVLT 3426
Query 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
V NP TPKY F ++PG+TF+VLA YNG P G + MR + TIKGSFL GSCGSVG+
Sbjct 3427 VTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVVMRSSHTIKGSFLCGSCGSVGY 3486
Query 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
+ D V F YMH +EL TG H GTD GNFYGP+ D Q Q D T TVNV+AWLYA
Sbjct 3487 VLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAWLYA 3546
Query 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
A++N WF+ + +L +FN+ AM + + D V L L++ TG+ V + A++K
Sbjct 3547 AILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVLAAIKR 3604
Query 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
L +G G+ ILGS +LEDE TP DV +Q +GV QS R IKGT W+L + +
Sbjct 3605 -LHSGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTFLFCSI 3663
Query 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
+ +W++F ++ + L + + FAM+ +KHKH +L ++++P L T+ Y N +
Sbjct 3664 ISAFVKWTMFMYVTTH-MLGVTLCALCFVIFAMLLIKHKHLYLTMYIMPVLCTLFYTNYL 3722
Query 3654 YMPASWVMRIM--TWLDMVDTSLSGFKLKDCVMYASAVVLLILM---TARTVYDDGARRV 3708
+ R + WL ++ + D V+Y VVLL+ M T R++ D +
Sbjct 3723 VVGYKQSFRGLAYAWLSYFVPAVD-YTYMDEVLY--GVVLLVAMVFVTMRSINHDVFSTM 3779
Query 3709 WTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARG-IVFMCVEYCP 3767
+ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA ++ +
Sbjct 3780 FLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKWLAVNV 3835
Query 3768 IFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQG 3827
++F ++ ++L Y +GY C CY+G+ LLN FR+ LGVY+Y +S QE RYMN+ G
Sbjct 3836 LYFTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISVQELRYMNANG 3895
Query 3828 LLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKL 3887
L PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+SKL
Sbjct 3896 LRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNSKL 3955
Query 3888 WAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATL 3941
W C LHN+IL D + AF+K+ LL VL + AVD I ++ ++ + + L
Sbjct 3956 WQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNTVL 4015
Query 3942 QAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRK 4000
QA+ SEF ++ S+ + A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ RK
Sbjct 4016 QALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARK 4075
Query 4001 LEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLN 4060
LE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN
Sbjct 4076 LERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLN 4135
Query 4061 IIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSP 4120
IP T+ L +++PD + D TYA +W IQ + DAD + QL+EI ++++
Sbjct 4136 AIPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDVNST- 4194
Query 4121 NLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGG 4178
WPL+++A R N S V LQNNEL P LR +G+ + YYNTT G
Sbjct 4195 ---WPLVISANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNC--NIPTQCYYNTTGTG 4249
Query 4179 RFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLN 4238
+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L
Sbjct 4250 KIVYAILSDCDGLKYTKIVKEDGN-CVVLELDPPCKFSVQDVKGLKIKYLYFVKGCNTLA 4308
Query 4239 RGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKML 4298
RG V+G+L++TVRLQAG ATE +NS +LS CAF+VD K Y DY+ GG P+TNCVKML
Sbjct 4309 RGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIQQGGVPVTNCVKML 4368
Query 4299 CTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCAN 4358
C H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P
Sbjct 4369 CDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-IK 4427
Query 4359 DPVGFTLKNTVCTVCGMWKGYGCSC 4383
DPV + L + VC VCG W+ CSC
Sbjct 4428 DPVSYVLTHDVCQVCGFWRDGSCSC 4452
Score = 88.2 bits (217), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 239/1025 (23%), Positives = 394/1025 (38%), Gaps = 219/1025 (21%)
Query 2 ESLVPGFNEKTHVQLS---LPVLQ-------VRDVLVRGFGDSVEEVLSEARQHLKDGTC 51
E V G HV++ LP L+ +RD+ V + ++V + L+ G+
Sbjct 46 EPKVKGKTLVNHVRVDCSRLPALECCVQSAIIRDIFV---DEDPQKVEASTMMALQFGSA 102
Query 52 GLVEVEK----------GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQY 97
LV+ K GVLP+ +F + T HV +L + +G+
Sbjct 103 VLVKPSKRLSVQAWAKLGVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCL 162
Query 98 GRSGETLGVLVPHVGEIPVAYRK------VLLRKNGNKGA---GGHSYGADLKSFDLGDE 148
G +G +G VP V IP ++ +LLRK GNKG+ G + +D E
Sbjct 163 G-NGRFIGWFVP-VTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE 220
Query 149 LGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARA 208
D E+ N K+S L+R G +VD C G C+ L
Sbjct 221 ---DACEEVHLNPRGKYSCK-AYALLRGYRGVKPILFVDQYGCDYTG----CLAKGLEDY 272
Query 209 GKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKS-YELQTPFEIKLAKKF---- 263
G TLSE + R ++E +AW+ +R ++ LQT ++ +
Sbjct 273 GDL--TLSEMKELSPVWRDSL---DNEVVVAWHVDRDPRAVMRLQTLATVRSIEYVGQPI 327
Query 264 -DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLS 318
D +G+ P + N+I+K + PR+ + L Y +S E C
Sbjct 328 EDMVDGDVVMREPAHLLAPNAIVKRL-PRLVETML----------YTDSSVTE---FCYK 373
Query 319 TLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPAC----- 373
T + CD CG + Q G +V + CG G++P N + CP C
Sbjct 374 TKL-CD-CGFIT-QFG-YVDCCGDTCGFR----------GWVPGNMMDGFPCPGCCKSYM 419
Query 374 ------HNSEVGPEHSL--AEYHNESGLKTILRKGGRTIAFGGCVF--SYVGCHNKCAYW 423
+S V PE + + + ++ G + FGG + Y G W
Sbjct 420 PWELEAQSSGVIPEGGVLFTQSTDTVNRESFKLYGHAVVPFGGAAYWSPYPG------MW 473
Query 424 VPRASANIGC----NHTGVVG-EGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILA 478
+P +++ +TGVVG + D + L + V + G+ E+ AI+
Sbjct 474 LPVIWSSVKSYSYLTYTGVVGCKAIVQETDAICRFLYMDYVQ-HKCGNL---EQRAIL-- 527
Query 479 SFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFAS 538
GLD +Q++ + G++ + +L + F
Sbjct 528 --------------GLDDVYHRQLLVNRGDYSL-----------------LLENVDLFVK 556
Query 539 EAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA-MMFTSDLATNNLVV 597
R+ F+ T + + L +LDG+ S LI + FTS + + V
Sbjct 557 R-----RAEFACKFATCGDGLVPL------LLDGLVPRSYYLIKSGQAFTSLMVNFSREV 605
Query 598 ------MAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRD------G 645
MA + V++ ++++ + G V + K + + K E + D G
Sbjct 606 VDMCMDMALLFMHDVKVATKYVKKVTGKVAVRFKALGIAVVRKITEWFDLAVDTAASAAG 665
Query 646 WEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNL 705
W + ++ V ++T +E+ E V+ F F + DS+ + ++
Sbjct 666 WLCYQLVN--GLFAVANGVITFIQEVPELVKNFVDKFKTFFKVLIDSMSV------SILS 717
Query 706 GETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVL---TEEVVLKTGD 762
G T V + R C+ A ++ + ++LP ++ E G+
Sbjct 718 GLTVVKTASN--RVCL-------------AGSKVYEVVQKSLPAYIMPVGCSEATCLVGE 762
Query 763 LQP--LEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEK-YCALAPN----MMVTNNTFTL 815
++P E + V+APL C +I +K Y A + ++V N+T +
Sbjct 763 IEPAVFEDDVVDVVKAPLTYQGCCKPPSSFEKICIVDKLYMAKCGDQFYPVVVDNDTVGV 822
Query 816 KGG------APTKVTFGDD-TVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEV 868
A KV F D V EV + + I F LD D VL++ CS + V+ +
Sbjct 823 LDQCWRFPCAGKKVVFNDKPKVKEVPSTRKIKIIFALDATFDSVLSKACSEFEVDKDVTL 882
Query 869 NEFACVVADAVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFY 925
+E VV DAV TL P E + T + L+ YLFDE GE +AS MYCSF
Sbjct 883 DELLDVVLDAVESTLSPCKEHGVIGTKVCALLERLVDDYVYLFDEGGEEVIASRMYCSFS 942
Query 926 PPDED 930
PDED
Sbjct 943 APDED 947
Score = 59.7 bits (143), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 52/153 (34%), Positives = 82/153 (54%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV D+++ ++V V+VN AN + HG GVAGA+ KA A E+ D +
Sbjct 1319 ITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKAFINETADMVKA 1378
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNV--NKGEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G +VGG +G L K L++VGP+ + E LL+ AY++ N+ + ++ L+SA
Sbjct 1379 QGVCQVGGCYESTGGKLCKKVLNIVGPDARGHGNECYSLLERAYQHINKCDNVVTTLISA 1438
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + V NV L +++ +D
Sbjct 1439 GIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFD 1471
Score = 40.0 bits (92), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 52/213 (24%), Positives = 84/213 (39%), Gaps = 25/213 (12%)
Query 1596 PTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLR-VEAFEYYHTTDPSFLGRYMSALNHTK 1654
P ++ D+ K++ E +T P D T V AF+ ++ S S H K
Sbjct 1047 PDQVEAFDIEKVEDSILSELQTELNAPADKTYEDVLAFDAIYSETLSAFYAVPSDETHFK 1106
Query 1655 KWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALI 1714
V G S NC+L + L+ +Q + L+F +Q + +AG F +
Sbjct 1107 ------VCGFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKL 1160
Query 1715 LAYCNKT-VGELGDVRETMSYLFQHANLDSC--KRVLNVVCKTCGQQQTTLKGVEAVMYM 1771
+ K+ + G +Y F L C K N C CG + L+G++AV +
Sbjct 1161 VKSAPKSIILPQGGYVADFAYFF----LSQCSFKVHANWRCLKCG-MELKLQGLDAVFFY 1215
Query 1772 GTLSYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
G + V C CG T L+ + P+
Sbjct 1216 GDV--------VSHMCKCGNSMT--LLSADIPY 1238
>sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus
133/2005 OX=389230 GN=1a PE=3 SV=1
Length=4441
Score = 1831 bits (4744), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 955/2183 (44%), Positives = 1372/2183 (63%), Gaps = 55/2183 (3%)
Query 2255 SNLGMPSYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDSLDTYPSLETIQITISS 2313
S LG+ + C G Y N T+ + +C+ S+ C CL G DSL Y +L+ +Q I+S
Sbjct 2274 SYLGIRTLCDGLAVEYRN-TSFDVVDFCSNRSVLCQWCLIGQDSLTRYSALQMLQTHITS 2332
Query 2314 FKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFA--VHFISNSWLMWLIINL 2371
+ ++ E+FLAY+L+T F VL L Q FF+Y + V++ + ++++ + L
Sbjct 2333 YVLNIDWIWFALEFFLAYVLYTSSFNVLLLVVTAQYFFAYTSAFVNWRAYNYIVSGLFFL 2392
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
V P+ +VR+Y F A +++ K Y HV++GC + C++CYKRNR TRVE +TIV G +
Sbjct 2393 VTHIPLHGLVRVYNFLACLWFLRKFYSHVINGCKDTACLLCYKRNRLTRVEASTIVCGTK 2452
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R+FY+ ANGG +C HNWNCV CDT G+TFI EVA DL+ +R I PTDQS Y V
Sbjct 2453 RTFYIAANGGTSYCCKHNWNCVECDTAGVGNTFICTEVANDLTTTLRRLIKPTDQSHYYV 2512
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRAN---NTKGSLP-INVIVFDGKS 2547
DSV VK+ + L++++ G YER+ L +F NL+ L+ T +P N +++D
Sbjct 2513 DSVVVKDAVVELHYNRDGSSCYERYPLCYFTNLEKLKFKEVCKTPTGIPEHNFLIYDTND 2572
Query 2548 KCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPME 2607
+ +E+ A+SA VYYSQ++C+P+LL+D LV+ VGDS E+A+KM D+++N+F S F+V +
Sbjct 2573 RGQENLARSACVYYSQVLCKPMLLVDVNLVTTVGDSREIAIKMLDSFINSFISLFSVSRD 2632
Query 2608 KLKTLVATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDVETKDVVECLKLSHQSDIEVT 2666
KL+ L+ TA + + VL TF AAR V+SDVET VV+ L+ +H++DI++T
Sbjct 2633 KLEKLINTARDCVRRGDDFQTVLKTFTDAARGHAGVESDVETTMVVDALQYAHKNDIQLT 2692
Query 2667 GDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLR 2726
+ NNY+ Y K +++ DLG ID A +N ++ N A +WN D+M LS+ +
Sbjct 2693 TECYNNYVPGYIKPDSINTLDLGCLIDLKAASVNQTSMRNANGACVWNSGDYMKLSDSFK 2752
Query 2727 KQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVN---NWLKQLIKVTL----- 2778
+QIR A +K N+PF+LT + R N+++ K + KIV +WL ++ +T+
Sbjct 2753 RQIRIACRKCNIPFRLTTSKLRAADNILSVKFS--ATKIVGGAPSWLLRVRDLTVKGYCI 2810
Query 2779 --VFLF-VAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFD 2835
+F+F VA + + P + ++ I+ YK I+ G+ RDIA D CFANK+ F
Sbjct 2811 LTLFVFTVAVLSWFCLPSYSIATVNFNDDRILTYKVIENGIVRDIAPNDACFANKYGHFS 2870
Query 2836 TWFSQ-RGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGN 2894
WF++ GG Y N CP+ AVI G V +P T L + F+ RVF A N
Sbjct 2871 KWFNENHGGVYRNSVDCPITIAVIAGVAGARVANVPAT-LAWVGRQIVLFVSRVF-ANTN 2928
Query 2895 ICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRY 2954
+C+TP+ I Y F+ S CVL++ECT+F+DA G P+CYD VL G+ +Y ++P RY
Sbjct 2929 VCFTPTNEIPYDTFSDSGCVLSSECTLFRDAEGNLNPFCYDPTVLPGASSYADMKPHVRY 2988
Query 2955 VLMDGSI-IQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRS 3013
+ D + I+FP E ++R+ T ++YCR G+CE S AGVC+ST+G W L N Y +
Sbjct 2989 DMYDSDMYIKFPEVIFESTLRITKTLATQYCRFGSCEESAAGVCISTNGSWALYNQNYST 3048
Query 3014 LPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGE 3073
PG++CG D +++ + L QP+ +S S+ G ++ + +T YY + +RA +
Sbjct 3049 RPGIYCGDDYFDIVRRLAVSLFQPVTYFQLSTSLAMGLVLCVFLTAAFYYINKVKRALAD 3108
Query 3074 YSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFT 3133
Y+ + L++ LC L Y+ +Y Y TFYLT + +F+ HI W VMF
Sbjct 3109 YTQCAVVAVVAALLNSLCLCFIVANPLLVAPYTAMYYYATFYLTGEPAFIMHISWYVMFG 3168
Query 3134 PLVPFWITIAYIICISTKHFYWFFSNYLKRRV-VF-NGVSFSTFEEAALCTFLLNKEMYL 3191
+VP W+ +Y + + +H +W + + K+ V VF +G +F++AA F++ K+ Y+
Sbjct 3169 TVVPIWMLASYTVGVMLRHLFWVLAYFSKKHVDVFTDGKLNCSFQDAASNIFVIGKDTYV 3228
Query 3192 KLRSDVLLPLTQ--YNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVL 3249
LR+ +TQ + RYL+L+NKYKY