PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,282 sequences; 206,678,396 total letters
Results from round 1
Query= sp|P40189|IL6RB_HUMAN Interleukin-6 receptor subunit beta OS=Homo
sapiens OX=9606 GN=IL6ST PE=1 SV=2
Length=918
Score E
Sequences producing significant alignments: (Bits) Value
sp|P40189|IL6RB_HUMAN Interleukin-6 receptor subunit beta OS=Homo... 1917 0.0
sp|P40190|IL6RB_RAT Interleukin-6 receptor subunit beta OS=Rattus... 1441 0.0
sp|Q00560|IL6RB_MOUSE Interleukin-6 receptor subunit beta OS=Mus ... 1434 0.0
sp|Q8NI17|IL31R_HUMAN Interleukin-31 receptor subunit alpha OS=Ho... 237 2e-65
sp|Q99062|CSF3R_HUMAN Granulocyte colony-stimulating factor recep... 238 5e-65
sp|Q8K5B1|IL31R_MOUSE Interleukin-31 receptor subunit alpha OS=Mu... 212 8e-57
sp|P40223|CSF3R_MOUSE Granulocyte colony-stimulating factor recep... 197 4e-51
sp|P42702|LIFR_HUMAN Leukemia inhibitory factor receptor OS=Homo ... 171 2e-42
sp|Q5XNR9|LIFR_CANLF Leukemia inhibitory factor receptor OS=Canis... 166 1e-40
sp|Q99665|I12R2_HUMAN Interleukin-12 receptor subunit beta-2 OS=H... 157 4e-38
sp|Q8MJS1|I12R2_PIG Interleukin-12 receptor subunit beta-2 OS=Sus... 155 2e-37
sp|P97378|I12R2_MOUSE Interleukin-12 receptor subunit beta-2 OS=M... 153 7e-37
sp|Q9BEG2|I12R2_BOVIN Interleukin-12 receptor subunit beta-2 OS=B... 152 2e-36
sp|P42703|LIFR_MOUSE Leukemia inhibitory factor receptor OS=Mus m... 151 5e-36
sp|O70535|LIFR_RAT Leukemia inhibitory factor receptor OS=Rattus ... 145 3e-34
sp|Q65Z14|OSMR_RAT Oncostatin-M-specific receptor subunit beta OS... 138 6e-32
sp|O70458|OSMR_MOUSE Oncostatin-M-specific receptor subunit beta ... 132 3e-30
sp|Q9JM58|CRLF1_MOUSE Cytokine receptor-like factor 1 OS=Mus musc... 125 2e-29
sp|O75462|CRLF1_HUMAN Cytokine receptor-like factor 1 OS=Homo sap... 123 9e-29
sp|Q99650|OSMR_HUMAN Oncostatin-M-specific receptor subunit beta ... 125 5e-28
sp|P48356|LEPR_MOUSE Leptin receptor OS=Mus musculus OX=10090 GN=... 107 2e-22
sp|O02671|LEPR_PIG Leptin receptor OS=Sus scrofa OX=9823 GN=LEPR ... 103 5e-21
sp|Q62959|LEPR_RAT Leptin receptor OS=Rattus norvegicus OX=10116 ... 102 1e-20
sp|Q9MYL0|LEPR_MACMU Leptin receptor OS=Macaca mulatta OX=9544 GN... 94.7 2e-18
sp|P48357|LEPR_HUMAN Leptin receptor OS=Homo sapiens OX=9606 GN=L... 94.0 4e-18
sp|O46561|PRLR_SHEEP Prolactin receptor OS=Ovis aries OX=9940 GN=... 85.9 6e-16
sp|Q28172|PRLR_BOVIN Prolactin receptor OS=Bos taurus OX=9913 GN=... 84.7 1e-15
sp|P05710|PRLR_RAT Prolactin receptor OS=Rattus norvegicus OX=101... 84.7 1e-15
sp|Q08501|PRLR_MOUSE Prolactin receptor OS=Mus musculus OX=10090 ... 84.3 2e-15
sp|Q6JTA8|PRLR_PIG Prolactin receptor OS=Sus scrofa OX=9823 GN=PR... 82.8 6e-15
sp|P14787|PRLR_RABIT Prolactin receptor OS=Oryctolagus cuniculus ... 81.6 1e-14
sp|Q28235|PRLR_CEREL Prolactin receptor OS=Cervus elaphus OX=9860... 80.9 2e-14
sp|Q04594|PRLR_CHICK Prolactin receptor OS=Gallus gallus OX=9031 ... 80.9 3e-14
sp|O70394|I27RA_MOUSE Interleukin-27 receptor subunit alpha OS=Mu... 79.7 5e-14
sp|Q91094|PRLR_MELGA Prolactin receptor OS=Meleagris gallopavo OX... 79.7 8e-14
sp|Q90374|PRLR_COLLI Prolactin receptor OS=Columba livia OX=8932 ... 78.6 1e-13
sp|Q8AV58|SDK1_CHICK Protein sidekick-1 OS=Gallus gallus OX=9031 ... 79.0 2e-13
sp|Q8K4B4|IL23R_MOUSE Interleukin-23 receptor OS=Mus musculus OX=... 77.8 2e-13
sp|P16471|PRLR_HUMAN Prolactin receptor OS=Homo sapiens OX=9606 G... 72.8 7e-12
sp|A7MBJ4|PTPRF_BOVIN Receptor-type tyrosine-protein phosphatase ... 73.6 7e-12
sp|A2A8L5|PTPRF_MOUSE Receptor-type tyrosine-protein phosphatase ... 70.9 5e-11
sp|Q64604|PTPRF_RAT Receptor-type tyrosine-protein phosphatase F ... 70.5 7e-11
sp|Q08406|CNTFR_RAT Ciliary neurotrophic factor receptor subunit ... 67.4 2e-10
sp|P23468|PTPRD_HUMAN Receptor-type tyrosine-protein phosphatase ... 68.9 2e-10
sp|Q7Z5N4|SDK1_HUMAN Protein sidekick-1 OS=Homo sapiens OX=9606 G... 68.9 2e-10
sp|Q64487|PTPRD_MOUSE Receptor-type tyrosine-protein phosphatase ... 68.6 2e-10
sp|Q91513|PRLR_ORENI Prolactin receptor OS=Oreochromis niloticus ... 67.8 3e-10
sp|P10586|PTPRF_HUMAN Receptor-type tyrosine-protein phosphatase ... 68.2 3e-10
sp|O88507|CNTFR_MOUSE Ciliary neurotrophic factor receptor subuni... 66.2 4e-10
sp|P26992|CNTFR_HUMAN Ciliary neurotrophic factor receptor subuni... 65.5 8e-10
sp|Q6V4S5|SDK2_MOUSE Protein sidekick-2 OS=Mus musculus OX=10090 ... 66.6 9e-10
sp|Q5VWK5|IL23R_HUMAN Interleukin-23 receptor OS=Homo sapiens OX=... 65.5 1e-09
sp|Q6UWB1|I27RA_HUMAN Interleukin-27 receptor subunit alpha OS=Ho... 65.5 2e-09
sp|Q71DR4|CNTFR_CANLF Ciliary neurotrophic factor receptor subuni... 63.9 3e-09
sp|P51641|CNTFR_CHICK Ciliary neurotrophic factor receptor subuni... 63.2 4e-09
sp|Q3UH53|SDK1_MOUSE Protein sidekick-1 OS=Mus musculus OX=10090 ... 64.3 5e-09
sp|Q810U4|NRCAM_MOUSE Neuronal cell adhesion molecule OS=Mus musc... 64.3 5e-09
sp|A2ABU4|MYOM3_MOUSE Myomesin-3 OS=Mus musculus OX=10090 GN=Myom... 63.9 6e-09
sp|A4IFW2|PTPRF_DANRE Receptor-type tyrosine-protein phosphatase ... 63.5 9e-09
sp|Q58EX2|SDK2_HUMAN Protein sidekick-2 OS=Homo sapiens OX=9606 G... 63.2 1e-08
sp|P97686|NRCAM_RAT Neuronal cell adhesion molecule OS=Rattus nor... 62.4 2e-08
sp|Q92823|NRCAM_HUMAN Neuronal cell adhesion molecule OS=Homo sap... 61.6 3e-08
sp|Q8IWV2|CNTN4_HUMAN Contactin-4 OS=Homo sapiens OX=9606 GN=CNTN... 58.9 2e-07
sp|P29322|EPHA8_HUMAN Ephrin type-A receptor 8 OS=Homo sapiens OX... 58.5 3e-07
sp|O09127|EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus musculus OX... 58.2 4e-07
sp|Q5VTT5|MYOM3_HUMAN Myomesin-3 OS=Homo sapiens OX=9606 GN=MYOM3... 57.4 7e-07
sp|Q99MF4|I11RA_RAT Interleukin-11 receptor subunit alpha OS=Ratt... 56.2 9e-07
sp|O94779|CNTN5_HUMAN Contactin-5 OS=Homo sapiens OX=9606 GN=CNTN... 56.6 1e-06
sp|P08887|IL6RA_HUMAN Interleukin-6 receptor subunit alpha OS=Hom... 55.5 1e-06
sp|Q9N3X8|SDK_CAEEL Protein sidekick homolog OS=Caenorhabditis el... 56.2 2e-06
sp|P22273|IL6RA_RAT Interleukin-6 receptor subunit alpha OS=Rattu... 55.5 2e-06
sp|Q62845|CNTN4_RAT Contactin-4 OS=Rattus norvegicus OX=10116 GN=... 55.8 2e-06
sp|Q8WZ42|TITIN_HUMAN Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=4 56.2 2e-06
sp|Q0E9H9|DSCA1_DROME Cell adhesion molecule Dscam1 OS=Drosophila... 55.8 2e-06
sp|Q62682|CNTN3_RAT Contactin-3 OS=Rattus norvegicus OX=10116 GN=... 55.5 2e-06
sp|Q69Z26|CNTN4_MOUSE Contactin-4 OS=Mus musculus OX=10090 GN=Cnt... 55.5 3e-06
sp|P70225|I11RB_MOUSE Interleukin-11 receptor subunit alpha-2 OS=... 54.7 3e-06
sp|Q64385|I11RA_MOUSE Interleukin-11 receptor subunit alpha-1 OS=... 54.7 3e-06
sp|Q64605|PTPRS_RAT Receptor-type tyrosine-protein phosphatase S ... 55.1 3e-06
sp|B0V2N1|PTPRS_MOUSE Receptor-type tyrosine-protein phosphatase ... 55.1 3e-06
sp|Q8K3K1|USH2A_RAT Usherin OS=Rattus norvegicus OX=10116 GN=Ush2... 55.1 4e-06
sp|Q07409|CNTN3_MOUSE Contactin-3 OS=Mus musculus OX=10090 GN=Cnt... 54.3 5e-06
sp|Q2QI47|USH2A_MOUSE Usherin OS=Mus musculus OX=10090 GN=Ush2A P... 54.7 5e-06
sp|Q13332|PTPRS_HUMAN Receptor-type tyrosine-protein phosphatase ... 53.5 9e-06
sp|A2ASS6|TITIN_MOUSE Titin OS=Mus musculus OX=10090 GN=Ttn PE=1 ... 53.1 1e-05
sp|Q14626|I11RA_HUMAN Interleukin-11 receptor subunit alpha OS=Ho... 52.4 1e-05
sp|Q5RF19|I11RA_PONAB Interleukin-11 receptor subunit alpha OS=Po... 51.6 2e-05
sp|Q61772|EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus musculus OX... 51.6 3e-05
sp|O75445|USH2A_HUMAN Usherin OS=Homo sapiens OX=9606 GN=USH2A PE... 52.0 3e-05
sp|P22272|IL6RA_MOUSE Interleukin-6 receptor subunit alpha OS=Mus... 51.2 4e-05
sp|Q8AV57|SDK2_CHICK Protein sidekick-2 OS=Gallus gallus OX=9031 ... 51.6 4e-05
sp|P54759|EPHA7_RAT Ephrin type-A receptor 7 OS=Rattus norvegicus... 51.2 5e-05
sp|F1NWE3|PTPRS_CHICK Receptor-type tyrosine-protein phosphatase ... 51.2 5e-05
sp|P97527|CNTN5_RAT Contactin-5 OS=Rattus norvegicus OX=10116 GN=... 50.8 6e-05
sp|G5EF96|UNC40_CAEEL Netrin receptor unc-40 OS=Caenorhabditis el... 50.8 6e-05
sp|Q8VHZ8|DSCAM_RAT Cell adhesion molecule DSCAM OS=Rattus norveg... 50.8 6e-05
sp|Q9ERC8|DSCAM_MOUSE Cell adhesion molecule DSCAM OS=Mus musculu... 50.8 6e-05
sp|O18796|IL6RA_PIG Interleukin-6 receptor subunit alpha OS=Sus s... 50.1 7e-05
sp|Q60ZN5|SDK_CAEBR Protein sidekick homolog OS=Caenorhabditis br... 50.8 8e-05
sp|Q15375|EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo sapiens OX... 50.4 8e-05
sp|P14781|CNTN1_CHICK Contactin-1 OS=Gallus gallus OX=9031 GN=CNT... 50.4 8e-05
sp|Q63155|DCC_RAT Netrin receptor DCC OS=Rattus norvegicus OX=101... 49.7 1e-04
sp|P70211|DCC_MOUSE Netrin receptor DCC OS=Mus musculus OX=10090 ... 49.7 1e-04
sp|O42422|EPHA7_CHICK Ephrin type-A receptor 7 OS=Gallus gallus O... 49.7 1e-04
sp|P43146|DCC_HUMAN Netrin receptor DCC OS=Homo sapiens OX=9606 G... 49.7 1e-04
sp|P78552|I13R1_HUMAN Interleukin-13 receptor subunit alpha-1 OS=... 48.9 2e-04
sp|O60469|DSCAM_HUMAN Cell adhesion molecule DSCAM OS=Homo sapien... 49.3 2e-04
sp|Q8TDY8|IGDC4_HUMAN Immunoglobulin superfamily DCC subclass mem... 48.5 3e-04
sp|Q9UF33|EPHA6_HUMAN Ephrin type-A receptor 6 OS=Homo sapiens OX... 48.5 3e-04
sp|Q9UQ52|CNTN6_HUMAN Contactin-6 OS=Homo sapiens OX=9606 GN=CNTN... 48.5 4e-04
sp|Q62413|EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus musculus OX... 48.1 4e-04
sp|Q9EQS9|IGDC4_MOUSE Immunoglobulin superfamily DCC subclass mem... 48.1 4e-04
sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 OS=Homo sapiens OX... 48.1 4e-04
sp|P54758|EPHA6_RAT Ephrin type-A receptor 6 OS=Rattus norvegicus... 47.8 5e-04
sp|P0C5E4|PTPRQ_MOUSE Phosphatidylinositol phosphatase PTPRQ OS=M... 48.1 5e-04
sp|P97798|NEO1_MOUSE Neogenin OS=Mus musculus OX=10090 GN=Neo1 PE... 47.8 5e-04
sp|A5HJM1|IL7RA_CALJA Interleukin-7 receptor subunit alpha OS=Cal... 47.0 6e-04
sp|H2A0L7|FND1_PINMG Fibronectin type III domain-containing prote... 47.4 7e-04
sp|P13944|COCA1_CHICK Collagen alpha-1(XII) chain OS=Gallus gallu... 47.4 8e-04
sp|P68500|CNTN5_MOUSE Contactin-5 OS=Mus musculus OX=10090 GN=Cnt... 47.0 9e-04
sp|Q90610|NEO1_CHICK Neogenin (Fragment) OS=Gallus gallus OX=9031... 46.6 0.001
sp|P52179|MYOM1_HUMAN Myomesin-1 OS=Homo sapiens OX=9606 GN=MYOM1... 46.6 0.001
sp|Q92859|NEO1_HUMAN Neogenin OS=Homo sapiens OX=9606 GN=NEO1 PE=... 46.2 0.001
sp|F1NY98|DSCAM_CHICK Cell adhesion molecule DSCAM OS=Gallus gall... 46.2 0.002
sp|Q9VN14|CONT_DROME Contactin OS=Drosophila melanogaster OX=7227... 46.2 0.002
sp|P32004|L1CAM_HUMAN Neural cell adhesion molecule L1 OS=Homo sa... 46.2 0.002
sp|P34902|IL2RG_MOUSE Cytokine receptor common subunit gamma OS=M... 45.4 0.002
sp|Q38IC7|IL7RA_MACFA Interleukin-7 receptor subunit alpha OS=Mac... 45.8 0.002
sp|Q2EY13|PRTGB_DANRE Protogenin B (Fragment) OS=Danio rerio OX=7... 46.2 0.002
sp|P16871|IL7RA_HUMAN Interleukin-7 receptor subunit alpha OS=Hom... 45.4 0.002
sp|P97603|NEO1_RAT Neogenin (Fragment) OS=Rattus norvegicus OX=10... 46.2 0.002
sp|P97528|CNTN6_RAT Contactin-6 OS=Rattus norvegicus OX=10116 GN=... 45.8 0.002
sp|Q7TPD3|ROBO2_MOUSE Roundabout homolog 2 OS=Mus musculus OX=100... 46.2 0.002
sp|O88488|PTPRQ_RAT Phosphatidylinositol phosphatase PTPRQ OS=Rat... 45.8 0.002
sp|P16621|LAR_DROME Tyrosine-protein phosphatase Lar OS=Drosophil... 45.8 0.002
sp|Q60629|EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus musculus OX... 45.4 0.003
sp|O97394|SDK_DROME Protein sidekick OS=Drosophila melanogaster O... 45.4 0.003
sp|Q4VA61|DSCL1_MOUSE Cell adhesion molecule DSCAML1 OS=Mus muscu... 45.4 0.003
sp|E1C8P7|DSCL1_CHICK Cell adhesion molecule DSCAML1 OS=Gallus ga... 45.4 0.003
sp|Q80X19|COEA1_MOUSE Collagen alpha-1(XIV) chain OS=Mus musculus... 45.1 0.004
sp|Q8TD84|DSCL1_HUMAN Cell adhesion molecule DSCAML1 OS=Homo sapi... 45.1 0.004
sp|Q00993|UFO_MOUSE Tyrosine-protein kinase receptor UFO OS=Mus m... 44.7 0.005
sp|P54755|EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallus gallus O... 44.7 0.005
sp|Q99715|COCA1_HUMAN Collagen alpha-1(XII) chain OS=Homo sapiens... 44.7 0.005
sp|Q9P232|CNTN3_HUMAN Contactin-3 OS=Homo sapiens OX=9606 GN=CNTN... 44.7 0.005
sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 OS=Rattus norvegicus... 44.3 0.005
sp|Q00546|TENR_CHICK Tenascin-R OS=Gallus gallus OX=9031 GN=TNR P... 43.5 0.010
sp|Q7ZW34|CNTN5_DANRE Contactin-5 OS=Danio rerio OX=7955 GN=cntn5... 43.5 0.010
sp|Q9BMN8|LAR_CAEEL Tyrosine-protein phosphatase Lar-like OS=Caen... 43.5 0.011
sp|Q03145|EPHA2_MOUSE Ephrin type-A receptor 2 OS=Mus musculus OX... 43.5 0.011
sp|Q14213|IL27B_HUMAN Interleukin-27 subunit beta OS=Homo sapiens... 42.0 0.012
sp|Q05707|COEA1_HUMAN Collagen alpha-1(XIV) chain OS=Homo sapiens... 43.5 0.012
sp|Q9HCK4|ROBO2_HUMAN Roundabout homolog 2 OS=Homo sapiens OX=960... 43.5 0.012
sp|P54296|MYOM2_HUMAN Myomesin-2 OS=Homo sapiens OX=9606 GN=MYOM2... 43.1 0.013
sp|P35331|NRCAM_CHICK Neuronal cell adhesion molecule OS=Gallus g... 43.1 0.014
sp|Q9Y6N7|ROBO1_HUMAN Roundabout homolog 1 OS=Homo sapiens OX=960... 43.1 0.016
sp|Q95118|IL2RG_BOVIN Cytokine receptor common subunit gamma OS=B... 42.4 0.016
sp|Q810U3|NFASC_MOUSE Neurofascin OS=Mus musculus OX=10090 GN=Nfa... 42.7 0.016
sp|Q9UMZ3|PTPRQ_HUMAN Phosphatidylinositol phosphatase PTPRQ OS=H... 42.7 0.018
sp|Q86VF2|IGFN1_HUMAN Immunoglobulin-like and fibronectin type II... 42.4 0.022
sp|Q95LF0|I13R2_CANLF Interleukin-13 receptor subunit alpha-2 OS=... 42.0 0.024
sp|O89026|ROBO1_MOUSE Roundabout homolog 1 OS=Mus musculus OX=100... 42.4 0.024
sp|P97685|NFASC_RAT Neurofascin OS=Rattus norvegicus OX=10116 GN=... 42.4 0.025
sp|Q9TU69|GHR_CANLF Growth hormone receptor OS=Canis lupus famili... 42.0 0.028
sp|Q9JMB8|CNTN6_MOUSE Contactin-6 OS=Mus musculus OX=10090 GN=Cnt... 42.0 0.030
sp|Q28106|CNTN1_BOVIN Contactin-1 OS=Bos taurus OX=9913 GN=CNTN1 ... 42.0 0.030
sp|A2A863|ITB4_MOUSE Integrin beta-4 OS=Mus musculus OX=10090 GN=... 42.0 0.031
sp|P28693|EPHB2_CHICK Ephrin type-B receptor 2 OS=Gallus gallus O... 42.0 0.032
sp|Q90344|EPHB2_COTJA Ephrin type-B receptor 2 OS=Coturnix japoni... 42.0 0.033
sp|P54764|EPHA4_HUMAN Ephrin type-A receptor 4 OS=Homo sapiens OX... 42.0 0.035
sp|Q63198|CNTN1_RAT Contactin-1 OS=Rattus norvegicus OX=10116 GN=... 41.6 0.038
sp|Q9MYZ9|EPOR_PIG Erythropoietin receptor OS=Sus scrofa OX=9823 ... 41.2 0.039
sp|Q12860|CNTN1_HUMAN Contactin-1 OS=Homo sapiens OX=9606 GN=CNTN... 41.6 0.040
sp|Q967D7|TUTL_DROME Protein turtle OS=Drosophila melanogaster OX... 41.6 0.041
sp|P26954|IL3B2_MOUSE Interleukin-3 receptor class 2 subunit beta... 41.6 0.042
sp|Q64632|ITB4_RAT Integrin beta-4 OS=Rattus norvegicus OX=10116 ... 41.2 0.051
sp|P40321|IL2RG_CANLF Cytokine receptor common subunit gamma OS=C... 40.8 0.056
sp|P29320|EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo sapiens OX... 41.2 0.058
sp|P12960|CNTN1_MOUSE Contactin-1 OS=Mus musculus OX=10090 GN=Cnt... 40.8 0.062
sp|O13146|EPHA3_DANRE Ephrin type-A receptor 3 OS=Danio rerio OX=... 40.8 0.065
sp|A0MSX9|IL7RA_HORSE Interleukin-7 receptor subunit alpha OS=Equ... 40.4 0.065
sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mu... 40.8 0.069
sp|Q91145|COCA1_NOTVI Collagen alpha-1(XII) chain (Fragment) OS=N... 40.8 0.069
sp|Q4KMG0|CDON_HUMAN Cell adhesion molecule-related/down-regulate... 40.8 0.072
sp|Q6PDN3|MYLK_MOUSE Myosin light chain kinase, smooth muscle OS=... 40.8 0.076
sp|O09030|I13R1_MOUSE Interleukin-13 receptor subunit alpha-1 OS=... 40.0 0.082
sp|P54763|EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus musculus OX... 40.4 0.082
sp|Q90478|L1CA1_DANRE Neural cell adhesion molecule L1.1 (Fragmen... 40.4 0.085
sp|Q90W79|CNTN5_CHICK Contactin-5 OS=Gallus gallus OX=9031 GN=CNT... 40.4 0.089
sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens OX... 40.4 0.091
sp|Q91694|EPA4B_XENLA Ephrin type-A receptor 4-B OS=Xenopus laevi... 40.4 0.096
sp|Q15746|MYLK_HUMAN Myosin light chain kinase, smooth muscle OS=... 40.4 0.098
sp|P29319|EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus musculus OX... 40.4 0.098
sp|Q2KL21|EPOR_CANLF Erythropoietin receptor OS=Canis lupus famil... 40.0 0.11
sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens OX... 40.0 0.11
sp|Q60847|COCA1_MOUSE Collagen alpha-1(XII) chain OS=Mus musculus... 40.4 0.12
sp|P0DSP1|SORL_RAT Sortilin-related receptor OS=Rattus norvegicus... 40.0 0.13
sp|P08941|ROS1_CHICK Proto-oncogene tyrosine-protein kinase ROS O... 40.0 0.13
sp|Q8VHK6|I13R2_RAT Interleukin-13 receptor subunit alpha-2 OS=Ra... 39.7 0.13
sp|Q4W815|EPOR_XENLA Erythropoietin receptor OS=Xenopus laevis OX... 39.7 0.13
sp|Q03137|EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus musculus OX... 40.0 0.14
sp|Q78DX7|ROS1_MOUSE Proto-oncogene tyrosine-protein kinase ROS O... 40.0 0.14
sp|Q7ZX59|CRLF3_XENLA Cytokine receptor-like factor 3 OS=Xenopus ... 39.3 0.14
sp|Q4ZHG4|FNDC1_HUMAN Fibronectin type III domain-containing prot... 40.0 0.15
sp|Q91736|EPB1B_XENLA Ephrin type-B receptor 1-B (Fragment) OS=Xe... 39.7 0.16
sp|O35158|CDON_RAT Cell adhesion molecule-related/down-regulated ... 39.7 0.16
sp|Q05695|L1CAM_RAT Neural cell adhesion molecule L1 OS=Rattus no... 39.7 0.16
sp|O14522|PTPRT_HUMAN Receptor-type tyrosine-protein phosphatase ... 39.7 0.18
sp|Q63257|IL4RA_RAT Interleukin-4 receptor subunit alpha OS=Rattu... 39.3 0.19
sp|Q99M80|PTPRT_MOUSE Receptor-type tyrosine-protein phosphatase ... 39.7 0.19
sp|Q8CBF3|EPHB1_MOUSE Ephrin type-B receptor 1 OS=Mus musculus OX... 39.3 0.19
sp|Q91845|EPA4A_XENLA Ephrin type-A receptor 4-A OS=Xenopus laevi... 39.3 0.19
sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens OX... 39.3 0.19
sp|O08680|EPHA3_RAT Ephrin type-A receptor 3 OS=Rattus norvegicus... 39.3 0.20
sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 OS=Rattus norvegicus... 39.3 0.21
sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens OX... 39.3 0.22
sp|H2A0L8|FND2_PINMG Fibronectin type III domain-containing prote... 38.9 0.23
sp|P14753|EPOR_MOUSE Erythropoietin receptor OS=Mus musculus OX=1... 38.9 0.23
sp|Q32MD9|CDON_MOUSE Cell adhesion molecule-related/down-regulate... 39.3 0.23
sp|Q14627|I13R2_HUMAN Interleukin-13 receptor subunit alpha-2 OS=... 38.5 0.24
sp|Q589G5|PRTG_CHICK Protogenin OS=Gallus gallus OX=9031 GN=PRTG ... 39.3 0.24
sp|Q53EP0|FND3B_HUMAN Fibronectin type III domain-containing prot... 39.3 0.24
sp|Q62234|MYOM1_MOUSE Myomesin-1 OS=Mus musculus OX=10090 GN=Myom... 39.3 0.25
sp|Q91735|EPHB3_XENLA Ephrin type-B receptor 3 OS=Xenopus laevis ... 38.9 0.25
sp|P19756|GHR_PIG Growth hormone receptor OS=Sus scrofa OX=9823 G... 38.9 0.26
sp|B1AUH1|PTPRU_MOUSE Receptor-type tyrosine-protein phosphatase ... 38.9 0.27
sp|O88307|SORL_MOUSE Sortilin-related receptor OS=Mus musculus OX... 38.9 0.28
sp|Q63132|ROS1_RAT Proto-oncogene tyrosine-protein kinase ROS OS=... 38.9 0.28
sp|P22105|TENX_HUMAN Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB P... 38.9 0.29
sp|P31785|IL2RG_HUMAN Cytokine receptor common subunit gamma OS=H... 38.5 0.29
sp|Q07496|EPHA4_CHICK Ephrin type-A receptor 4 OS=Gallus gallus O... 38.9 0.29
sp|Q60805|MERTK_MOUSE Tyrosine-protein kinase Mer OS=Mus musculus... 38.9 0.31
sp|P32018|COEA1_CHICK Collagen alpha-1(XIV) chain OS=Gallus gallu... 38.9 0.31
sp|Q1KL86|EPHA2_MACFA Ephrin type-A receptor 2 OS=Macaca fascicul... 38.5 0.31
sp|Q6WG24|IL4RA_HORSE Interleukin-4 receptor subunit alpha OS=Equ... 38.5 0.32
sp|Q28902|COCA1_RABIT Collagen alpha-1(XII) chain (Fragment) OS=O... 38.5 0.32
sp|Q9R044|NPHN_RAT Nephrin OS=Rattus norvegicus OX=10116 GN=Nphs1... 38.5 0.33
sp|P28192|PTP4_CAEEL Tyrosine-protein phosphatase 4 OS=Caenorhabd... 38.5 0.33
sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo ... 38.5 0.38
sp|P57097|MERTK_RAT Tyrosine-protein kinase Mer OS=Rattus norvegi... 38.5 0.38
sp|Q02173|MPSF_CHICK M-protein, striated muscle OS=Gallus gallus ... 38.5 0.39
sp|Q28824|MYLK_BOVIN Myosin light chain kinase, smooth muscle OS=... 38.5 0.40
sp|Q3KNY0|IGFN1_MOUSE Immunoglobulin-like and fibronectin type II... 38.5 0.41
sp|Q973G3|Y939_SULTO Kelch domain-containing protein STK_09390 OS... 38.1 0.42
sp|P19941|GHR_RABIT Growth hormone receptor OS=Oryctolagus cunicu... 37.7 0.50
sp|P16170|NCA11_XENLA Neural cell adhesion molecule 1-A OS=Xenopu... 38.1 0.51
sp|B3EX02|MFP1_ACRMI MAM and fibronectin type III domain-containi... 37.4 0.56
sp|P33896|INAR1_MOUSE Interferon alpha/beta receptor 1 OS=Mus mus... 37.7 0.59
sp|P79108|GHR_BOSIN Growth hormone receptor OS=Bos indicus OX=991... 37.7 0.60
sp|P31836|NCAM1_BOVIN Neural cell adhesion molecule 1 OS=Bos taur... 37.7 0.62
sp|Q98902|L1CAM_TAKRU Neural cell adhesion molecule L1 OS=Takifug... 37.7 0.66
sp|P16872|IL7RA_MOUSE Interleukin-7 receptor subunit alpha OS=Mus... 37.4 0.66
sp|Q2VWP9|PRTG_RAT Protogenin OS=Rattus norvegicus OX=10116 GN=Pr... 37.7 0.67
sp|Q12866|MERTK_HUMAN Tyrosine-protein kinase Mer OS=Homo sapiens... 37.7 0.67
sp|O55005|ROBO1_RAT Roundabout homolog 1 OS=Rattus norvegicus OX=... 37.7 0.68
sp|O46600|GHR_BOVIN Growth hormone receptor OS=Bos taurus OX=9913... 37.4 0.68
sp|Q07303|EPOR_RAT Erythropoietin receptor OS=Rattus norvegicus O... 37.4 0.77
sp|Q2EY14|PRTGA_DANRE Protogenin A OS=Danio rerio OX=7955 GN=prtg... 37.4 0.79
sp|Q92673|SORL_HUMAN Sortilin-related receptor OS=Homo sapiens OX... 37.4 0.79
sp|Q2EY15|PRTG_MOUSE Protogenin OS=Mus musculus OX=10090 GN=Prtg ... 37.4 0.80
sp|Q9U308|JAC1_CAEEL Juxtamembrane domain-associated catenin OS=C... 37.4 0.81
sp|P29318|EPHA3_CHICK Ephrin type-A receptor 3 OS=Gallus gallus O... 37.4 0.89
sp|P16144|ITB4_HUMAN Integrin beta-4 OS=Homo sapiens OX=9606 GN=I... 37.4 0.90
sp|Q9QZS7|NPHN_MOUSE Nephrin OS=Mus musculus OX=10090 GN=Nphs1 PE... 37.0 0.96
sp|G5EBF1|SAX3_CAEEL Protein sax-3 OS=Caenorhabditis elegans OX=6... 37.0 0.98
sp|Q07498|EPHB3_CHICK Ephrin type-B receptor 3 (Fragment) OS=Gall... 37.0 1.0
sp|P13590|NCAM1_CHICK Neural cell adhesion molecule 1 OS=Gallus g... 37.0 1.0
sp|A0JM20|TYRO3_XENTR Tyrosine-protein kinase receptor TYRO3 OS=X... 37.0 1.1
sp|P26221|GUN4_THEFU Endoglucanase E-4 OS=Thermobifida fusca OX=2... 36.6 1.5
sp|Q8WZ75|ROBO4_HUMAN Roundabout homolog 4 OS=Homo sapiens OX=960... 36.2 1.6
sp|Q2VWP7|PRTG_HUMAN Protogenin OS=Homo sapiens OX=9606 GN=PRTG P... 36.2 1.7
sp|Q7Z7G0|TARSH_HUMAN Target of Nesh-SH3 OS=Homo sapiens OX=9606 ... 36.2 1.7
sp|O88786|I13R2_MOUSE Interleukin-13 receptor subunit alpha-2 OS=... 35.8 1.7
sp|P54761|EPHB4_MOUSE Ephrin type-B receptor 4 OS=Mus musculus OX... 36.2 1.7
sp|P13591|NCAM1_HUMAN Neural cell adhesion molecule 1 OS=Homo sap... 36.2 1.7
sp|E4URG0|M28P2_ARTGP Probable zinc metalloprotease MGYG_02393 OS... 35.8 1.8
sp|Q568M3|CRLF3_DANRE Cytokine receptor-like factor 3 OS=Danio re... 35.8 1.9
sp|Q96MS0|ROBO3_HUMAN Roundabout homolog 3 OS=Homo sapiens OX=960... 36.2 1.9
sp|Q9VS29|DSCL_DROME Cell adhesion molecule Dscam2 OS=Drosophila ... 36.2 2.0
sp|Q95209|SORL_RABIT Sortilin-related receptor OS=Oryctolagus cun... 36.2 2.1
sp|P08922|ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS O... 36.2 2.2
sp|Q8IWZ5|TRI42_HUMAN Tripartite motif-containing protein 42 OS=H... 35.8 2.2
sp|P32927|IL3RB_HUMAN Cytokine receptor common subunit beta OS=Ho... 35.8 2.4
sp|P24394|IL4RA_HUMAN Interleukin-4 receptor subunit alpha OS=Hom... 35.8 2.4
sp|Q02388|CO7A1_HUMAN Collagen alpha-1(VII) chain OS=Homo sapiens... 35.8 2.4
sp|P11627|L1CAM_MOUSE Neural cell adhesion molecule L1 OS=Mus mus... 35.8 2.5
sp|P34082|FAS2_DROME Fasciclin-2 OS=Drosophila melanogaster OX=72... 35.8 2.5
sp|H2KZ60|RIG6_CAEEL Contactin rig-6 OS=Caenorhabditis elegans OX... 35.8 2.5
sp|P29294|MYLK_RABIT Myosin light chain kinase, smooth muscle OS=... 35.8 2.5
sp|P20241|NRG_DROME Neuroglian OS=Drosophila melanogaster OX=7227... 35.4 2.8
sp|Q95JF2|GHR_AILME Growth hormone receptor OS=Ailuropoda melanol... 35.4 2.9
sp|O94856|NFASC_HUMAN Neurofascin OS=Homo sapiens OX=9606 GN=NFAS... 35.4 3.1
sp|P13596|NCAM1_RAT Neural cell adhesion molecule 1 OS=Rattus nor... 35.4 3.4
sp|P36335|NCA12_XENLA Neural cell adhesion molecule 1-B OS=Xenopu... 35.4 3.6
sp|Q9Z2L7|CRLF3_MOUSE Cytokine receptor-like factor 3 OS=Mus musc... 35.0 3.6
sp|Q863Z5|IL4RA_PIG Interleukin-4 receptor subunit alpha OS=Sus s... 35.0 3.7
sp|Q9Y2H6|FND3A_HUMAN Fibronectin type-III domain-containing prot... 35.0 3.9
sp|O00533|NCHL1_HUMAN Neural cell adhesion molecule L1-like prote... 35.0 4.0
sp|Q28575|GHR_SHEEP Growth hormone receptor OS=Ovis aries OX=9940... 35.0 4.0
sp|Q6DFV6|FN3C1_MOUSE Fibronectin type III domain containing prot... 35.0 4.1
sp|Q8K9T7|DLDH_BUCAP Dihydrolipoyl dehydrogenase OS=Buchnera aphi... 34.7 4.2
sp|Q9U4G1|BDL_DROME Protein borderless OS=Drosophila melanogaster... 35.0 4.2
sp|Q6NWW9|FND3B_MOUSE Fibronectin type III domain-containing prot... 35.0 4.5
sp|Q9I7U4|TITIN_DROME Titin OS=Drosophila melanogaster OX=7227 GN... 35.0 4.6
sp|Q80W87|ROBO4_RAT Roundabout homolog 4 OS=Rattus norvegicus OX=... 35.0 4.6
sp|Q5RBN1|FND3A_PONAB Fibronectin type-III domain-containing prot... 34.7 4.8
sp|Q98930|SORL_CHICK Sortilin-related receptor (Fragment) OS=Gall... 34.7 5.0
sp|Q90Z04|CDON_XENLA Cell adhesion molecule-related/down-regulate... 34.7 5.2
sp|G5EC23|HCF1_CAEEL Host cell factor homolog hcf-1 OS=Caenorhabd... 34.7 5.3
sp|Q6YI48|PTPRU_CHICK Receptor-type tyrosine-protein phosphatase ... 34.7 5.4
sp|Q9D2H5|TRI42_MOUSE Tripartite motif-containing protein 42 OS=M... 34.7 5.4
sp|O42414|NFASC_CHICK Neurofascin OS=Gallus gallus OX=9031 GN=NFA... 34.7 5.4
sp|G4SLH0|TTN1_CAEEL Titin homolog OS=Caenorhabditis elegans OX=6... 34.7 5.8
sp|Q2Q0I9|FNDC1_RAT Fibronectin type III domain-containing protei... 34.7 6.0
sp|P11799|MYLK_CHICK Myosin light chain kinase, smooth muscle OS=... 34.7 6.5
sp|O02466|ILPR_BRALA Insulin-like peptide receptor OS=Branchiosto... 34.3 7.0
sp|B8VIW9|FP_ACRMI Fibronectin type III domain-containing protein... 34.3 7.3
sp|Q02246|CNTN2_HUMAN Contactin-2 OS=Homo sapiens OX=9606 GN=CNTN... 34.3 7.8
sp|Q5ZJP5|FND3A_CHICK Fibronectin type-III domain-containing prot... 34.3 8.1
sp|Q97Z97|Y1033_SACS2 Kelch domain-containing protein SSO1033 OS=... 33.9 8.6
sp|P26955|IL3RB_MOUSE Cytokine receptor common subunit beta OS=Mu... 33.9 8.6
sp|P10039|TENA_CHICK Tenascin OS=Gallus gallus OX=9031 GN=TNC PE=... 33.9 9.2
sp|Q9HBE5|IL21R_HUMAN Interleukin-21 receptor OS=Homo sapiens OX=... 33.5 9.6
>sp|P40189|IL6RB_HUMAN Interleukin-6 receptor subunit beta OS=Homo
sapiens OX=9606 GN=IL6ST PE=1 SV=2
Length=918
Score = 1917 bits (4966), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 918/918 (100%), Positives = 918/918 (100%), Gaps = 0/918 (0%)
Query 1 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV 60
MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV
Sbjct 1 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV 60
Query 61 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI 120
NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI
Sbjct 61 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI 120
Query 121 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT
Sbjct 121 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL
Sbjct 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR
Sbjct 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN
Sbjct 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
Query 361 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD
Sbjct 361 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT
Sbjct 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD
Sbjct 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG
Sbjct 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK
Sbjct 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
Query 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN
Sbjct 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
Query 721 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS 780
TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS
Sbjct 721 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS 780
Query 781 ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV 840
ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV
Sbjct 781 ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV 840
Query 841 NEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEG 900
NEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEG
Sbjct 841 NEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEG 900
Query 901 MPKSYLPQTVRQGGYMPQ 918
MPKSYLPQTVRQGGYMPQ
Sbjct 901 MPKSYLPQTVRQGGYMPQ 918
>sp|P40190|IL6RB_RAT Interleukin-6 receptor subunit beta OS=Rattus
norvegicus OX=10116 GN=Il6st PE=1 SV=1
Length=918
Score = 1441 bits (3729), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 722/919 (79%), Positives = 803/919 (87%), Gaps = 2/919 (0%)
Query 1 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV 60
M L+ WL+QAL IFLTTES G+L++PCGYI PE PVVQ SNFTA CVLKEKC+ + V
Sbjct 1 MSALRIWLMQALLIFLTTESIGQLVEPCGYIYPEFPVVQRGSNFTATCVLKEKCLQVYSV 60
Query 61 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI 120
NA YIVWKTNH +PKEQ T+INRTASSVTFTD+ N+QLTCNIL+FGQ+EQNVYGITI
Sbjct 61 NATYIVWKTNHVAVPKEQVTVINRTASSVTFTDVVFQNVQLTCNILSFGQIEQNVYGITI 120
Query 121 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
+SG PP+ P NLSCIVNEGK M C+ D GRET+LETN+TLKSEWAT KF DC+ K T +
Sbjct 121 LSGYPPDIPTNLSCIVNEGKNMLCQLDPGRETYLETNYTLKSEWATEKFPDCRTKHGT-S 179
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
SC + Y+ +YFVNIEVWVEAENALG V+S+ INFDPV KVKP+PPHNLSV NSEELSSIL
Sbjct 180 SCMMGYTPIYFVNIEVWVEAENALGNVSSEPINFDPVDKVKPSPPHNLSVTNSEELSSIL 239
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
KL W N + S++ LK +IQYRTKDASTW Q+P EDT S R+SFTVQDLKPFTEYVFRIR
Sbjct 240 KLAWVNSGLDSILRLKSDIQYRTKDASTWIQVPLEDTVSPRTSFTVQDLKPFTEYVFRIR 299
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
+KE+GKGYWSDWSEEASG TYEDRPSKAPSFWYK++ +H Q YR+ +L+WKTLP EAN
Sbjct 300 SIKENGKGYWSDWSEEASGTTYEDRPSKAPSFWYKVNANHPQEYRSARLIWKTLPLSEAN 359
Query 361 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
GKILDYEV LT+ KS Q YTVN T+L VNLTN+RY+A+L RN+VGKS A VLTIP
Sbjct 360 GKILDYEVVLTQSKSVSQTYTVNGTELIVNLTNNRYVASLAARNVVGKSPATVLTIPGSH 419
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
F+A+HPV+DLKAFPKDN+LWVEWT P + V KYILEWCVLS+ +PCI DWQQEDGTV+RT
Sbjct 420 FKASHPVVDLKAFPKDNLLWVEWTPPSKPVNKYILEWCVLSENSPCIPDWQQEDGTVNRT 479
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
+LRG+L ESKCYLITVTPV+ GPGSPES+KAYLKQA PSKGPTVRTKKVGKNEAVLEWD
Sbjct 480 HLRGSLLESKCYLITVTPVFPGGPGSPESMKAYLKQAAPSKGPTVRTKKVGKNEAVLEWD 539
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
LPVDVQNGFIRNY+I YRT +G E V VDSSHTEYTLSSL+SDTLYMV MAAYT+EGG
Sbjct 540 HLPVDVQNGFIRNYSISYRTSVGKEMVVRVDSSHTEYTLSSLSSDTLYMVHMAAYTEEGG 599
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
KDGPEFTFTT KFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK
Sbjct 600 KDGPEFTFTTLKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 659
Query 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
SHIAQWSPHTPPRHNFNSKDQMYSD NFTDVSVVEIEAN+KKP P+DLKSLDLFKKEKI+
Sbjct 660 SHIAQWSPHTPPRHNFNSKDQMYSDANFTDVSVVEIEANNKKPCPDDLKSLDLFKKEKIS 719
Query 721 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS 780
TEGHSSGIGGSSCMSSSRPSISSS+ENES+Q+T+STVQYSTVVHSGYRHQVPSVQVFSRS
Sbjct 720 TEGHSSGIGGSSCMSSSRPSISSSEENESAQSTASTVQYSTVVHSGYRHQVPSVQVFSRS 779
Query 781 ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV 840
ESTQPLLDSEERPEDLQLVD VD GD ILPRQQYFKQ+CSQ +SPD+SHF RS QV S
Sbjct 780 ESTQPLLDSEERPEDLQLVDSVDSGDEILPRQQYFKQSCSQPGASPDVSHFGRSSQVPSG 839
Query 841 NEEDFVRLK-QQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDE 899
+EEDFVRLK QQ+SDHIS+ GS Q ++FQE S ADA G GT+GQ+ERFE+VGME A DE
Sbjct 840 SEEDFVRLKQQQVSDHISEPYGSEQRRLFQEGSVADALGTGTDGQIERFESVGMETAMDE 899
Query 900 GMPKSYLPQTVRQGGYMPQ 918
+ KSYLPQTVRQGGYMPQ
Sbjct 900 DISKSYLPQTVRQGGYMPQ 918
>sp|Q00560|IL6RB_MOUSE Interleukin-6 receptor subunit beta OS=Mus
musculus OX=10090 GN=Il6st PE=1 SV=2
Length=917
Score = 1434 bits (3713), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 708/919 (77%), Positives = 796/919 (87%), Gaps = 3/919 (0%)
Query 1 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV 60
M + WL QAL FLTTES G+LL+PCGYI PE PVVQ SNFTA+CVLKE C+ +++V
Sbjct 1 MSAPRIWLAQALLFFLTTESIGQLLEPCGYIYPEFPVVQRGSNFTAICVLKEACLQHYYV 60
Query 61 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI 120
NA+YIVWKTNH +P+EQ T+INRT SSVTFTD+ ++QLTCNIL+FGQ+EQNVYG+T+
Sbjct 61 NASYIVWKTNHAAVPREQVTVINRTTSSVTFTDVVLPSVQLTCNILSFGQIEQNVYGVTM 120
Query 121 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
+SG PP+KP NL+CIVNEGK M C+WD GRET+LETN+TLKSEWAT KF DC++K T
Sbjct 121 LSGFPPDKPTNLTCIVNEGKNMLCQWDPGRETYLETNYTLKSEWATEKFPDCQSKHGT-- 178
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
SC V Y Y+VNIEVWVEAENALGKV+S+ INFDPV KVKP PP+NLSV NSEELSSIL
Sbjct 179 SCMVSYMPTYYVNIEVWVEAENALGKVSSESINFDPVDKVKPTPPYNLSVTNSEELSSIL 238
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
KL+W + + ++ LK +IQYRTKDASTW Q+P EDT S R+SFTVQDLKPFTEYVFRIR
Sbjct 239 KLSWVSSGLGGLLDLKSDIQYRTKDASTWIQVPLEDTMSPRTSFTVQDLKPFTEYVFRIR 298
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
+K+ GKGYWSDWSEEASG TYEDRPS+ PSFWYK +PSH Q YR+V+L+WK LP EAN
Sbjct 299 SIKDSGKGYWSDWSEEASGTTYEDRPSRPPSFWYKTNPSHGQEYRSVRLIWKALPLSEAN 358
Query 361 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
GKILDYEV LT+ KS Q YTV T+LTVNLTNDRY+A+L RN VGKS AAVLTIP+
Sbjct 359 GKILDYEVILTQSKSVSQTYTVTGTELTVNLTNDRYVASLAARNKVGKSAAAVLTIPSPH 418
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
A + V++LKAFPKDN+LWVEWT P + V KYILEWCVLS+ APC+ DWQQED TV+RT
Sbjct 419 VTAAYSVVNLKAFPKDNLLWVEWTPPPKPVSKYILEWCVLSENAPCVEDWQQEDATVNRT 478
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
+LRG L ESKCY ITVTPV+A GPG ES+KAYLKQA P++GPTVRTKKVGKNEAVL WD
Sbjct 479 HLRGRLLESKCYQITVTPVFATGPGGSESLKAYLKQAAPARGPTVRTKKVGKNEAVLAWD 538
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
Q+PVD QNGFIRNY+I YRT +G E V+VDSSHTEYTLSSL+SDTLYMVRMAAYTDEGG
Sbjct 539 QIPVDDQNGFIRNYSISYRTSVGKEMVVHVDSSHTEYTLSSLSSDTLYMVRMAAYTDEGG 598
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK
Sbjct 599 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 658
Query 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEAN+KKP P+DLKS+DLFKKEK++
Sbjct 659 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANNKKPCPDDLKSVDLFKKEKVS 718
Query 721 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS 780
TEGHSSGIGGSSCMSSSRPSISS++ENES+Q+T+STVQYSTVVHSGYRHQVPSVQVFSRS
Sbjct 719 TEGHSSGIGGSSCMSSSRPSISSNEENESAQSTASTVQYSTVVHSGYRHQVPSVQVFSRS 778
Query 781 ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV 840
ESTQPLLDSEERPEDLQLVD VDGGD ILPRQ YFKQNCSQ E+ P+ISHFERS QV S
Sbjct 779 ESTQPLLDSEERPEDLQLVDSVDGGDEILPRQPYFKQNCSQPEACPEISHFERSNQVLSG 838
Query 841 NEEDFVRLK-QQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDE 899
NEEDFVRLK QQ+SDHISQ GS Q ++FQE S ADA G G +GQ+ERFE+VGME DE
Sbjct 839 NEEDFVRLKQQQVSDHISQPYGSEQRRLFQEGSTADALGTGADGQMERFESVGMETTIDE 898
Query 900 GMPKSYLPQTVRQGGYMPQ 918
+PKSYLPQTVRQGGYMPQ
Sbjct 899 EIPKSYLPQTVRQGGYMPQ 917
>sp|Q8NI17|IL31R_HUMAN Interleukin-31 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL31RA PE=1 SV=1
Length=732
Score = 237 bits (604), Expect = 2e-65, Method: Compositional matrix adjust.
Identities = 162/550 (29%), Positives = 264/550 (48%), Gaps = 12/550 (2%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA-THKFADCKAKRDTP---TS 181
P KP+N+SC+ K + C W G+ET T +T+K +A K +C T S
Sbjct 22 PAKPENISCVYYYRKNLTCTWSPGKETSY-TQYTVKRTYAFGEKHDNCTTNSSTSENRAS 80
Query 182 CTVDYSTVYFV-NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
C+ + N + VEAEN G + S + K PP V + ++
Sbjct 81 CSFFLPRITIPDNYTIEVEAENGDGVIKSHMTYWRLENIAKTEPPKIFRVKPVLGIKRMI 140
Query 241 KLTWTNPSIKSVII-LKYNIQYRTKDASTWSQIP-PEDTASTRSSFTVQDLKPFTEYVFR 298
++ W P + V LKY +++RT ++++W ++ ++ ++ + L+PFTEYV
Sbjct 141 QIEWIKPELAPVSSDLKYTLRFRTVNSTSWMEVNFAKNRKDKNQTYNLTGLQPFTEYVIA 200
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+RC ++ K +WSDWS+E G+T E+ P W + P+ G R V+L+WK
Sbjct 201 LRCAVKESK-FWSDWSQEKMGMTEEEAPCGL-ELWRVLKPAEADGRRPVRLLWKKARGAP 258
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNAT--KLTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
K L Y + + T+N T +L ++L + + ++ N +GKS A L I
Sbjct 259 VLEKTLGYNIWYYPESNTNLTETMNTTNQQLELHLGGESFWVSMISYNSLGKSPVATLRI 318
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
PA ++ + ++A ++ L V+W + V +++EW D P W+
Sbjct 319 PAIQEKSFQCIEVMQACVAEDQLVVKWQSSALDVNTWMIEWFPDVDSEPTTLSWESVSQA 378
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAV 536
+ T + L CY I+V P+ D G P SI+AY K+ PS+GP + + +G
Sbjct 379 TNWTIQQDKLKPFWCYNISVYPMLHDKVGEPYSIQAYAKEGVPSEGPETKVENIGVKTVT 438
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
+ W ++P + G I NYTIFY+ G + V+SS +Y L SL T Y+V++ A T
Sbjct 439 ITWKEIPKSERKGIICNYTIFYQAEGGKGFSKTVNSSILQYGLESLKRKTSYIVQVMAST 498
Query 597 DEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVP 656
GG +G F T F+ EI I + L+ +L V + K + + WP VP
Sbjct 499 SAGGTNGTSINFKTLSFSVFEIILITSLIGGGLLILIILTVAYGLKKPNKLTHLCWPTVP 558
Query 657 DPSKSHIAQW 666
+P++S IA W
Sbjct 559 NPAESSIATW 568
>sp|Q99062|CSF3R_HUMAN Granulocyte colony-stimulating factor receptor
OS=Homo sapiens OX=9606 GN=CSF3R PE=1 SV=1
Length=836
Score = 238 bits (606), Expect = 5e-65, Method: Compositional matrix adjust.
Identities = 222/813 (27%), Positives = 355/813 (44%), Gaps = 76/813 (9%)
Query 6 TWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNAN-Y 64
TW AL I L S L+ CG+IS +P+V L TA C++K+ C H++
Sbjct 10 TW--AALIILLLPGS----LEECGHISVSAPIVHLGDPITASCIIKQNCS---HLDPEPQ 60
Query 65 IVWKTNHFTIP--KEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIIS 122
I+W+ P ++Q S +T + L+C L +G Q + + + +
Sbjct 61 ILWRLGAELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSC-CLNWGNSLQILDQVELRA 119
Query 123 GLPPEKPKNLSCIVN-EGKKMRCEWDGGRETHLETNFTLKS-------EWATHKFADCKA 174
G PP P NLSC++N + C+W+ G ETHL T+FTLKS + DC
Sbjct 120 GYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVP 179
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
K C + + N+ +WV+AENALG S + DP+ VK PP ++ S
Sbjct 180 KDGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSP 239
Query 235 ELS----SILKLTWTNPSIKSVIILKYNIQYRT-KDASTWSQIPPEDTASTRSSFTVQDL 289
E + L+L W I K ++++ + ++W+ + P + + + + L
Sbjct 240 EAAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQ--YELCGL 297
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK---IDPSHTQGYRT 346
P T Y +IRC++ G+WSDWS T E P+ W++ +DP RT
Sbjct 298 LPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDP------RT 351
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV----NATKL--TVNLTNDRYLATL 400
VQL WK +P E +G+I Y V+ W+ Q + N T+L T +L ++ L
Sbjct 352 VQLFWKPVPLEEDSGRIQGYVVS---WRPSGQAGAILPLCNTTELSCTFHLPSEAQEVAL 408
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMD-LKAFPKD-NMLWVEWTTPRESVKKYILEWC 458
N G S P ++ P + L A +D + LWV W P + Y++EW
Sbjct 409 VAYNSAGTSRPT----PVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEWG 464
Query 459 VLSDKAPCITD-WQQE-DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ A W+ E +G L+ N+ + Y I VTP+Y D G + + AY ++
Sbjct 465 LGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQE 524
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
PS P + K +GK A LEW P ++ + +YTIF+ + +++S
Sbjct 525 MAPSHAPELHLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSFSAILNASSRG 584
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT--TPKFAQGEIEAIVVPVCLAFLLTTL 634
+ L L +LY + + A + G + T TP+ ++ I + + L
Sbjct 585 FVLHGLEPASLYHIHLMAASQAGATNSTVLTLMTLTPEGSELHIILGLFGLLLLLTCLCG 644
Query 635 LGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVV 694
L C R K +WP+VPDP+ S + W P F Q+ G +
Sbjct 645 TAWLCCSPNR---KNPLWPSVPDPAHSSLGSWVPTIMEEDAF----QLPGLGTPPITKLT 697
Query 695 EIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTS 754
+E ++KKP P + S + + + T + + G S++P +S TS
Sbjct 698 VLEEDEKKPVPWE--SHNSSETCGLPTLVQTYVLQGDPRAVSTQP--------QSQSGTS 747
Query 755 STVQYSTVVHSGYRHQVPSVQVFSRSESTQPLL 787
V Y ++ S P + R +STQPLL
Sbjct 748 DQVLYGQLLGSPTS---PGPGHYLRCDSTQPLL 777
>sp|Q8K5B1|IL31R_MOUSE Interleukin-31 receptor subunit alpha OS=Mus
musculus OX=10090 GN=Il31ra PE=1 SV=3
Length=716
Score = 212 bits (540), Expect = 8e-57, Method: Compositional matrix adjust.
Identities = 186/642 (29%), Positives = 293/642 (46%), Gaps = 60/642 (9%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNF--TLKSEWATHKFAD--CKAKRDTPTS 181
P KP+N+SC+ + + C W +ET+ +T++ TL + ++D +A P S
Sbjct 21 PTKPENISCVFYFDRNLTCTWRPEKETN-DTSYIVTLTYSYGKSNYSDNATEASYSFPRS 79
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
C + V V+A+N GKV SD + + K PP LSV + + + +
Sbjct 80 CAMPPDIC-----SVEVQAQNGDGKVKSDITYWHLISIAKTEPPIILSV--NPICNRMFQ 132
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+ W L +++RT ++S W+++ E+ + + L+ FTEYV +R
Sbjct 133 IQWKPREKTRGFPLVCMLRFRTVNSSHWTEVNFENC---KQVCNLTGLQAFTEYVLALRF 189
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
D + YWS WS+E + +T E+ P W ++P+ G R V+L+WK
Sbjct 190 RFNDSR-YWSKWSKEETRVTMEEVP-HVLDLWRILEPADMNGDRKVRLLWKKARGAPVLE 247
Query 362 KILDYEVTLTRWKSHLQNYTVNATKLTV--NLTNDRY---------LATLTVRNLVGKSD 410
K Y H+Q + N+T LT N+T +Y ++T N +GKS
Sbjct 248 KTFGY---------HIQYFAENSTNLTEINNITTQQYELLLMSQAHSVSVTSFNSLGKSQ 298
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWC--VLSDKAPCIT 468
A+L IP + + +KA+ + +L V W + +V +I+EW K P ++
Sbjct 299 EAILRIPDVHEKTFQYIKSMKAYIAEPLLVVNWQSSIPAVDTWIVEWLPEAAMSKFPALS 358
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTK 528
W+ + T + L CY I+V PV G P SI+AY K+ P KGP R +
Sbjct 359 -WESVSQVTNWTIEQDKLKPFTCYNISVYPVLGHRVGEPYSIQAYAKEGTPLKGPETRVE 417
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLY 588
+G A + W ++P +NGFI NYT+FY+ G E + V+S + L SLT T Y
Sbjct 418 NIGLRTATITWKEIPKSARNGFINNYTVFYQAEGGKELSKTVNSHALQCDLESLTRRTSY 477
Query 589 MVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIK 648
V + A T GG +G F T + EI + V LL ++ V F K + +
Sbjct 478 TVWVMASTRAGGTNGVRINFKTLSISVFEIVLLTSLVGGGLLLLSIKTVTFGLRKPNRLT 537
Query 649 KHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDL 708
P+VP+P++S +A W + K M GN D V ++ P P DL
Sbjct 538 PLCCPDVPNPAESSLATW------LGDGFKKSNMKETGNSGDTEDVVLKPC---PVPADL 588
Query 709 --KSLDLFKK--EKINTE----GHSSGIGGSS---CMSSSRP 739
K + F+ E + TE G +S +GG + S SRP
Sbjct 589 IDKLVVNFENFLEVVLTEEAGKGQASILGGEANEYVTSPSRP 630
>sp|P40223|CSF3R_MOUSE Granulocyte colony-stimulating factor receptor
OS=Mus musculus OX=10090 GN=Csf3r PE=1 SV=2
Length=837
Score = 197 bits (500), Expect = 4e-51, Method: Compositional matrix adjust.
Identities = 209/815 (26%), Positives = 343/815 (42%), Gaps = 80/815 (10%)
Query 8 LVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVW 67
L IFL + L+ CG+I PVV+L A C + C I+W
Sbjct 9 LTGVTLIFLLLPRS---LESCGHIEISPPVVRLGDPVLASCTISPNCSKL--DQQAKILW 63
Query 68 KTNHFTIPK--EQYTIINRTASS-VTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGL 124
+ I Q+ + + T S +T + L C ++ + Q + + +G
Sbjct 64 RLQDEPIQPGDRQHHLPDGTQESLITLPHLNYTQAFLFC-LVPWEDSVQLLDQAELHAGY 122
Query 125 PPEKPKNLSCIVN-EGKKMRCEWDGGRETHLETNFTLKS-------EWATHKFADCKAKR 176
PP P NLSC+++ + C+W+ G ETHL T+F LKS ++ DC AK+
Sbjct 123 PPASPSNLSCLMHLTTNSLVCQWEPGPETHLPTSFILKSFRSRADCQYQGDTIPDCVAKK 182
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
+ + + + +WV+AEN LG S + DP+ VK PP ++ ++
Sbjct 183 RQNNCSIPRKNLLLYQYMAIWVQAENMLGSSESPKLCLDPMDVVKLEPPMLQALDIGPDV 242
Query 237 SS----ILKLTWT--NPS--IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
S L L+W PS ++ L+Y Q + + + +P S++ F +
Sbjct 243 VSHQPGCLWLSWKPWKPSEYMEQECELRYQPQLKGANWTLVFHLP-----SSKDQFELCG 297
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSF----WYK---IDPSH 340
L Y ++RC++ G+WS WS + RP+ KAP+ W + +DP
Sbjct 298 LHQAPVYTLQMRCIRSSLPGFWSPWSP-----GLQLRPTMKAPTIRLDTWCQKKQLDP-- 350
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN-YTVNATKLTV--NLTNDRYL 397
G +VQL WK P E +G+I Y ++ + Q+ + N T+L+ L ++
Sbjct 351 --GTVSVQLFWKPTPLQEDSGQIQGYLLSWSSPDHQGQDIHLCNTTQLSCIFLLPSEAQN 408
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRESVKKYILE 456
TL N G S + + A V L A +D N +WV+W P + Y++E
Sbjct 409 VTLVAYNKAGTSSPTTVVFLENEGPA---VTGLHAMAQDLNTIWVDWEAPSLLPQGYLIE 465
Query 457 WCVLSDK-APCITDWQQE-DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
W + S W E +G + L+ N+ + Y ITV P+Y G P ++ +
Sbjct 466 WEMSSPSYNNSYKSWMIEPNGNITGILLKDNINPFQLYRITVAPLYPGIVGPPVNVYTFA 525
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI--RNYTIFYRTIIGNETAVNVDS 572
+ P P + K VG A LEW +P + G I +YTIF+ + +V ++
Sbjct 526 GERAPPHAPALHLKHVGTTWAQLEW--VPEAPRLGMIPLTHYTIFWADAGDHSFSVTLNI 583
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLT 632
S ++ L L +LY V + A + G + T T ++ + +CL L T
Sbjct 584 SLHDFVLKHLEPASLYHVYLMATSRAGSTNSTGLTLRT--LDPSDLNIFLGILCLVLLST 641
Query 633 TLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVS 692
T + C +R K W +VPDP+ S ++ W P F + D + ++
Sbjct 642 TCVVTWLCCKRRG--KTSFWSDVPDPAHSSLSSWLPTIMTEETFQLPS--FWDSSVPSIT 697
Query 693 VVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQN 752
+ DKKP D +S + G + + + I S++++
Sbjct 698 KITELEEDKKPTHWDSES---------SGNGSLPALVQAYVLQGDPREI--SNQSQPPSR 746
Query 753 TSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLL 787
T V Y V+ S P V + RS+STQPLL
Sbjct 747 TGDQVLYGQVLESPTS---PGVMQYIRSDSTQPLL 778
>sp|P42702|LIFR_HUMAN Leukemia inhibitory factor receptor OS=Homo
sapiens OX=9606 GN=LIFR PE=1 SV=1
Length=1097
Score = 171 bits (434), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 170/669 (25%), Positives = 286/669 (43%), Gaps = 71/669 (11%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYF--HVNANYIVWKTNHFTIPKEQYTIINRTASS 88
+ P+ V+ + S+ T CV +EK + H N I + I ++ + ++
Sbjct 254 VFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIKIRNISVSASSGTN 313
Query 89 VTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG 148
V FT E N++G I +G PP+ P+ L+C ++ K++ C W+
Sbjct 314 VVFT------------------TEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNP 355
Query 149 GRETHL----ETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW---VEAE 201
GR T L T++TL E + K+ K + + PT+ + N E++ + A
Sbjct 356 GRVTALVGPRATSYTL-VESFSGKYVRLK-RAEAPTNESYQLLFQMLPNQEIYNFTLNAH 413
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
N LG+ S I + KV P+ P + V + S+ +KL+W P + I I+
Sbjct 414 NPLGRSQST-ILVNITEKVYPHTPTSFKVKDIN--STAVKLSWHLPGNFAKINFLCEIEI 470
Query 262 RTKDASTWSQIPPEDTASTRSSFTV--QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ K S Q SS+ V L P+T Y FRIRC E WS WS +
Sbjct 471 K-KSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETF-WKWSKWSNKKQH 528
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--RWKSHL 377
+T E PSK P W + + + + + WK LP EANGKIL Y V+ + L
Sbjct 529 LTTEASPSKGPDTWRE----WSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSL 584
Query 378 QNYTVNATKLTVNLTNDRYLATLTVRNLVGK---SDAAVLTIPACDFQATHPVMDLKAFP 434
K + L + Y+ ++ +N VG S A + IP D + V K
Sbjct 585 SEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIEQVVGMGKG-- 642
Query 435 KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN-LAESKCYL 493
+ + W Y+++WC S PC+ DW++ T + + Y
Sbjct 643 ----ILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYN 698
Query 494 ITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
+ G S+ Y+++ P P + + +++W+ +PV+ GF+R
Sbjct 699 FFLYGCRNQGYQLLRSMIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRG 758
Query 554 YTIFY----------RTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
Y ++ R + + + V D S ++ L T Y + + AYTD
Sbjct 759 YLFYFGKGERDTSKMRVLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTD-- 816
Query 600 GKDGPEFTF--TTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPD 657
G GPE + T + + G I AI++PV +A ++ + +L C+ KR+ IK+ +P++P+
Sbjct 817 GGVGPEKSMYVVTKENSVGLIIAILIPVAVAVIVGVVTSIL-CYRKREWIKETFYPDIPN 875
Query 658 PSKSHIAQW 666
P Q+
Sbjct 876 PENCKALQF 884
>sp|Q5XNR9|LIFR_CANLF Leukemia inhibitory factor receptor OS=Canis
lupus familiaris OX=9615 GN=LIFR PE=2 SV=1
Length=1097
Score = 166 bits (420), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 166/668 (25%), Positives = 283/668 (42%), Gaps = 69/668 (10%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCM--DYFHVNANYIVWKTNHFTIPKEQYTIINRTASS 88
+ P+ V+ + S+ T CV +EK + N I + I ++ + ++
Sbjct 254 VFPQDKVILVGSDITFCCVTQEKVLSAQIGQTNCPLIHLDGENVAIKIHNISVSANSGTN 313
Query 89 VTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG 148
V FT E N++G I G PP+ P+ ++C + K++ C W+
Sbjct 314 VVFT------------------TEDNIFGTVIFVGYPPDIPQKVNCETYDLKEIVCTWNP 355
Query 149 GRETHL----ETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW---VEAE 201
GR T L T++TL E + K+ K + + PT+ + N E++ + A
Sbjct 356 GRPTALVGPRNTSYTL-FESFSGKYVRFK-RVEAPTNESYQLFFQMRPNQEIYNFTLNAR 413
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
N LG+ S I + KV P P ++ V + S+ + L+W P + I L I+
Sbjct 414 NPLGRSEST-ILINITEKVYPRIPTSIKVKDIN--STAVMLSWHLPGNFAKIKLLCQIEI 470
Query 262 -RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
+T + + ++ V L P+T Y FRIRC E WS WS E +
Sbjct 471 NKTNSVQELRNVTIKGVENSSYLVAVDKLNPYTIYTFRIRCSTETF-WKWSKWSNEKKYL 529
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV--TLTRWKSHLQ 378
T E PSK P W + + + + + WK LP EANGKIL Y V +L L
Sbjct 530 TTEAIPSKGPDTWRE----WSSDGKNLIIYWKPLPINEANGKILSYNVSCSLDEETQSLS 585
Query 379 NYTVNATKLTVNLTNDRYLATLTVRNLVGK---SDAAVLTIPACDFQATHPVMDLKAFPK 435
K + L + Y+ ++ +N VG S A + IP D + +A
Sbjct 586 EIPDPQHKAELQLDKNDYIISVVAKNSVGSSPPSKIASMEIPNDDLKVE------QAVGM 639
Query 436 DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC-YLI 494
N + + W Y+++WC S PC+ DW++ + + Y
Sbjct 640 GNGILLTWNYDPNMTCDYVIKWCNSSRSEPCLMDWKKVPSNSTEAVIESDQFRPGVRYSF 699
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
+ +G SI Y+++ P P + + +++W+ +PV+ GF+R Y
Sbjct 700 FLYGCRNEGYQLLRSIIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGY 759
Query 555 TIFY----------RTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
++ R + + + V D S ++ L T Y + + AYTD G
Sbjct 760 LFYFEKGERDTSKIRGLESGRSDIKVKNITDLSQKTLRIADLQGKTSYHLVLRAYTDGGM 819
Query 601 KDGPEFTF--TTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDP 658
GPE + T + + G I AI++PV +A ++ + +L C+ KR+ IK+ +P++P+P
Sbjct 820 --GPEKSMFVVTKENSVGLIIAILIPVAVAVIVGVVTSIL-CYRKREWIKETFYPDIPNP 876
Query 659 SKSHIAQW 666
Q+
Sbjct 877 ENCKALQF 884
>sp|Q99665|I12R2_HUMAN Interleukin-12 receptor subunit beta-2
OS=Homo sapiens OX=9606 GN=IL12RB2 PE=1 SV=1
Length=862
Score = 157 bits (397), Expect = 4e-38, Method: Compositional matrix adjust.
Identities = 177/682 (26%), Positives = 272/682 (40%), Gaps = 88/682 (13%)
Query 35 SPVVQLHSNFTAVCVLKEK--CMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
S V+ L S C LK + C Y N I+ + + F
Sbjct 38 SHVILLGSTVNITCSLKPRQGCFHYSRRNK-----------------LILYKFDRRINFH 80
Query 93 DIASLNIQLT----------CNILTFGQLEQNVYGITIISGLPPEKPKNLSCI-VNEGKK 141
SLN Q+T C + E + G I G+ PE+P+NLSCI E
Sbjct 81 HGHSLNSQVTGLPLGTTLFVCKLACINSDEIQICGAEIFVGVAPEQPQNLSCIQKGEQGT 140
Query 142 MRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAE 201
+ C W+ GR+THL T +TL+ K +D DY + +N+
Sbjct 141 VACTWERGRDTHLYTEYTLQLS-GPKNLTWQKQCKDI----YCDYLD-FGINLTPESPES 194
Query 202 NALGKVTS---------DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV 252
N KVT+ F + V+P PP ++ + + S L W + +
Sbjct 195 NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASVSRCTLYWRDEGL--- 251
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+L ++YR ++ W+ + + + + DLKPFTEY F+I KG WSD
Sbjct 252 -VLLNRLRYRPSNSRLWNMV---NVTKAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSD 307
Query 313 WSEEASGITYEDRPSKAPSFWY---KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
WSE T E+ P+ WY ID S Q + L WK L EA GKIL Y+VT
Sbjct 308 WSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQ----ISLFWKNLSVSEARGKILHYQVT 363
Query 370 ---LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI-PACDFQATH 425
LT K+ QN T + + TV + ++ N G S + I C+
Sbjct 364 LQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLPTRINIMNLCEAGLLA 423
Query 426 PV-MDLKAFPKDNMLWVEWTTPRE---SVKKYILEWCVL--SDKAPCITDWQQEDGTVHR 479
P + + DN+L V W PR+ +V++Y++EW L +W +
Sbjct 424 PRQVSANSEGMDNIL-VTWQPPRKDPSAVQEYVVEWRELHPGGDTQVPLNWLRSRPYNVS 482
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
+ N+ CY I V + D G SI K P GP + K ++ W
Sbjct 483 ALISENIKSYICYEIRVYALSGDQGGC-SSILGNSKHKAPLSGPHINAITEEKGSILISW 541
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
+ +PV Q G + +Y I+++ N + S + ++SL Y++ M A
Sbjct 542 NSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTAL 601
Query 596 TDEG-GKDGPEFTFTTPKFAQGEIE--AIVVP-VCLAFLLTTLLGVLFCFNKRDLIKKHI 651
T G G E F QG+ A V P +C+A ++ + + K ++ +
Sbjct 602 TAAGESSHGNEREFCL----QGKANWMAFVAPSICIAIIMVGIFSTHYFQQKVFVLLAAL 657
Query 652 WPN-----VPDPSKSHIAQWSP 668
P +PDP+ S A+ P
Sbjct 658 RPQWCSREIPDPANSTCAKKYP 679
>sp|Q8MJS1|I12R2_PIG Interleukin-12 receptor subunit beta-2 OS=Sus
scrofa OX=9823 GN=IL12RB2 PE=2 SV=1
Length=861
Score = 155 bits (391), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 171/654 (26%), Positives = 274/654 (42%), Gaps = 76/654 (12%)
Query 81 IINRTASSVTFTDIASLNIQLT----------CNILTFGQLEQNVYGITIISGLPPEKPK 130
I+ R + F SL+ Q+T C + + E + G I G+ PE+P+
Sbjct 69 ILYRFHRRIHFQRGHSLSSQVTGLPLGTTLFVCKLACSSKEEIRICGAEISVGVVPEQPQ 128
Query 131 NLSCI-VNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
N+SC+ E + C WD GR+THL T +TL+ + C+ Y
Sbjct 129 NVSCMQKGERGTVACSWDRGRDTHLYTAYTLQ--------LNGPKNLTWQKQCSDYYCDS 180
Query 190 YFVNIEV-----------WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
+ I + V A N+LG +S F + V+P PP ++ + S
Sbjct 181 LDLGINLPPESPESSYTAQVTAINSLGTASSLPSTFTFLDVVRPLPPWDIRIKCVNASVS 240
Query 239 ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
L W + + +L ++YR + +W+ + + + + + DLKPFTEY F+
Sbjct 241 TCTLQWRDEGL----VLLNRLRYRPVYSRSWNMV---NATNAKGRHDLVDLKPFTEYEFQ 293
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY---KIDPSHTQGYRTVQLVWKTLP 355
I KG WSDWSE T E P+ WY ID Q + L WK L
Sbjct 294 ISSKPHLQKGRWSDWSESLRTQTPEKEPTGMLDVWYMKQHIDYKRQQ----ISLFWKNLS 349
Query 356 PFEANGKILDYEVTL---TRWKSHLQNYT-VNATKLTVNLTNDRYLATLTVRNLVGKSDA 411
EA GKIL Y+VTL + LQN T N+ T+ T + A ++ N G S
Sbjct 350 LSEARGKILHYQVTLQEVAEGNATLQNITERNSWTWTIPRTGI-WAAAVSAANSKGSSLP 408
Query 412 AVLTIPACDFQATHPVMDLKAFPK--DNMLWVEWTTPRE---SVKKYILEWCVLSDKA-- 464
+ I + A P+ DN+L V+WT+P E +V++Y++EW L +
Sbjct 409 TRINIADLCGAGLLAPQQVSANPEGSDNLL-VKWTSPGEGATAVQEYVVEWRELHLRGGM 467
Query 465 -PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
P ++ W + T + N+ CY I V + D G SI+ LK P GP
Sbjct 468 QPPLS-WLRSPPYNTSTLISDNIKPYICYEIRVHALSGDQGGC-SSIRGDLKHKAPLSGP 525
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTL 579
+ K ++ WD++P Q G I +Y I+++ + + S + +
Sbjct 526 HINAISEEKGSILISWDEIPAQEQMGCILHYRIYWKERDSDSQPQLCEIPYRVSPKSHPI 585
Query 580 SSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVP-VCLAFLLTTLLGV 637
+SL Y++ M A T G G E F + V P +C+A + +
Sbjct 586 NSLQPRVTYVLWMTALTAAGESPQGNEREFCLQ--GKANWSTFVAPSICIAVITVGVFS- 642
Query 638 LFCFNKRDLI----KKHIWPN--VPDPSKSHIAQWSPHTPPRHNFNSKDQMYSD 685
+ CF ++ + + W + +PDP+ S A+ P + S D++ +D
Sbjct 643 MRCFRQKVFVLLLALRPQWCSREIPDPANSTWAKKYPIVEEKKQL-SLDRLLAD 695
>sp|P97378|I12R2_MOUSE Interleukin-12 receptor subunit beta-2
OS=Mus musculus OX=10090 GN=Il12rb2 PE=1 SV=1
Length=874
Score = 153 bits (387), Expect = 7e-37, Method: Compositional matrix adjust.
Identities = 172/694 (25%), Positives = 293/694 (42%), Gaps = 65/694 (9%)
Query 12 LFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVL--KEKCMDYFHVNANYIVWKT 69
LF++L ++ ++ +PV+ L S C L K+ C Y N ++
Sbjct 15 LFMWLLIKANIDVCKLGTVTVQPAPVIPLGSAANISCSLNPKQGCSHYPSSNELILLKFV 74
Query 70 NHFTIPK-EQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQN------VYGITIIS 122
N + + + T S TF + +L++ +T + V G+ I
Sbjct 75 NDVLVENLHGKKVHDHTGHSSTF-QVTNLSLGMTLFVCKLNCSNSQKKPPVPVCGVEISV 133
Query 123 GLPPEKPKNLSCIV-NEGKKMRCEWDGGRETHLETNFTLKSEWATHK------FADCKA- 174
G+ PE P+N+SC+ E + C W+ G+ T+L+TN+TL+ + F+D +
Sbjct 134 GVAPEPPQNISCVQEGENGTVACSWNSGKVTYLKTNYTLQLSGPNNLTCQKQCFSDNRQN 193
Query 175 --KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
+ D + + D + F+ V V A N LG +S F + V P PP ++ +
Sbjct 194 CNRLDLGINLSPDLAESRFI---VRVTAINDLGNSSSLPHTFTFLDIVIPLPPWDIRINF 250
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
S L W + + ++L ++Y+ ++++W+ + + + + + ++DL+PF
Sbjct 251 LNASGSRGTLQWED---EGQVVLN-QLRYQPLNSTSWNMV---NATNAKGKYDLRDLRPF 303
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY---KIDPSHTQGYRTVQL 349
TEY F+I G WS+WSE T E+ P WY ID Q + L
Sbjct 304 TEYEFQISSKLHLSGGSWSNWSESLRTRTPEEEPVGILDIWYMKQDIDYDRQQ----ISL 359
Query 350 VWKTLPPFEANGKILDYEVTLTRW--KSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG 407
WK+L P EA GKIL Y+VTL K+ LQN T + + V + A+++ N G
Sbjct 360 FWKSLNPSEARGKILHYQVTLQEVTKKTTLQNTTRHTSWTRVIPRTGAWTASVSAANSKG 419
Query 408 KSDAA---VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE---SVKKYILEWCVLS 461
S ++ + A H V K+ DN+L V W P++ +V++YI+EW L
Sbjct 420 ASAPTHINIVDLCGTGLLAPHQV-SAKSENMDNIL-VTWQPPKKADSAVREYIVEWRALQ 477
Query 462 DKAPCITD----WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
+ IT W + + N+ CY I V + ++ G SI+ K
Sbjct 478 PGS--ITKFPPHWLRIPPDNMSALISENIKPYICYEIRVHAL-SESQGGCSSIRGDSKHK 534
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR----TIIGNETAVNVDSS 573
P GP + K + W +P Q G I +Y I+++ T + S
Sbjct 535 APVSGPHITAITEKKERLFISWTHIPFPEQRGCILHYRIYWKERDSTAQPELCEIQYRRS 594
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLT 632
+ +SSL Y++ M A T G G E F P+ ++ +C+A +
Sbjct 595 QNSHPISSLQPRVTYVLWMTAVTAAGESPQGNEREF-CPQGKANWKAFVISSICIAIITV 653
Query 633 TLLGVLFCFNKRDLIKKHIWPN-----VPDPSKS 661
+ + K + + P +PDP+ S
Sbjct 654 GTFSIRYFRQKAFTLLSTLKPQWYSRTIPDPANS 687
>sp|Q9BEG2|I12R2_BOVIN Interleukin-12 receptor subunit beta-2
OS=Bos taurus OX=9913 GN=IL12RB2 PE=2 SV=1
Length=861
Score = 152 bits (383), Expect = 2e-36, Method: Compositional matrix adjust.
Identities = 172/673 (26%), Positives = 273/673 (41%), Gaps = 70/673 (10%)
Query 35 SPVVQLHSNFTAVCVLKEK--CMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
S V+ L S C LK K C+ N I++K + + +++ ++ T
Sbjct 38 SHVISLGSAVNISCSLKPKQGCLPSSSFN-KLILYKFDRRIYVQHGHSLSSQVKGLPLGT 96
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCI-VNEGKKMRCEWDGGRE 151
+ C + E + G I G+ PE+P+NLSCI E + C W GR+
Sbjct 97 TL------FVCKLACSSSDEIRICGAEISVGVVPEQPRNLSCIQKGERGTVTCTWHRGRD 150
Query 152 THLETNFTLK---------SEWATHKFADCK--AKRDTPTSCTVDYSTVYFVNIEVWVEA 200
THL T +TL+ + + D TP S Y+ V V A
Sbjct 151 THLYTAYTLQLNGPKNLTWQKQCNDHYCDHLDLGINLTPESLESSYT--------VKVTA 202
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQ 260
N+LG +S +F + V+P PP ++ + L W + + +L ++
Sbjct 203 INSLGSASSFPFSFTLLDIVRPLPPWDIRIKFVNASVDRCTLLWRDEGL----VLLNRLR 258
Query 261 YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
YR ++ +W+ + + + + + DLKPFTEY F+I KG WSDWSE
Sbjct 259 YRPINSRSWNMV---NVTNAKGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSESLRTQ 315
Query 321 TYEDRPSKAPSFWY---KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH- 376
T E+ P + WY ID + Q + L WK L EA GKIL Y+VTL +
Sbjct 316 TPEEEPIGMLNVWYMRQHIDYNRQQ----ISLFWKNLSLSEARGKILHYQVTLQKVAGGE 371
Query 377 --LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP-ACDFQATHPVMDLKAF 433
LQN T + + V + A ++ N G S + I C + P L
Sbjct 372 ITLQNITEHTSWTWVIPRTGNWAAAVSAANSKGSSLPTRINITDLCGAELLAPQQVLAKS 431
Query 434 PKDNMLWVEWTTPRE---SVKKYILEWCVLSDKA---PCITDWQQEDGTVHRTYLRGNLA 487
+ L V WT P + +V++Y++EW L A P + W + N+
Sbjct 432 EGMDKLMVTWTPPEKATAAVQEYVVEWRELHPGAGMQPPL-GWLWSPPYRLSALISENIK 490
Query 488 ESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
CY I V + D G S + + P GP + K ++ WD++P Q
Sbjct 491 PYICYEIRVHALAGDQGGC-NSTRGNSQHKAPLSGPHINAISEEKGSVLISWDEIPAREQ 549
Query 548 NGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKD 602
G I +Y I+++ N + S + + SL Y++ M A T G
Sbjct 550 MGCILHYRIYWKERDSNSQPQLCEIPYRISPNSHPIDSLQPRVTYVLWMTALTAAGESPQ 609
Query 603 GPEFTFTTPKFAQGEIEAIVVP-VCLAFLLTTLLGVLFCFNKRDLI----KKHIW--PNV 655
G E F + V P +C+A ++ +L + CF ++ + + W +
Sbjct 610 GNEREFCLQ--GKANWSTFVAPSICMAVIMVGVLS-MRCFRQKVFVLLLALRPQWCSKEI 666
Query 656 PDPSKSHIAQWSP 668
PDP+ S A+ P
Sbjct 667 PDPANSTWAKKYP 679
>sp|P42703|LIFR_MOUSE Leukemia inhibitory factor receptor OS=Mus
musculus OX=10090 GN=Lifr PE=1 SV=1
Length=1092
Score = 151 bits (381), Expect = 5e-36, Method: Compositional matrix adjust.
Identities = 144/600 (24%), Positives = 258/600 (43%), Gaps = 79/600 (13%)
Query 112 EQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHL----ETNFTLKSEWATH 167
+ +VYG + +G PP+ P+ LSC ++ K++ C W+ GR T L T +TL
Sbjct 314 DDDVYGTVVFAGYPPDVPQKLSCETHDLKEIICSWNPGRITGLVGPRNTEYTL------- 366
Query 168 KFADCKAKRDTPTSCTVDYSTVYFVNIEVW---------VEAENALGKVTSDHINFDPVY 218
F K + Y + +++ + N LG+ S + +
Sbjct 367 -FESISGKSAVFHRIEGLTNETYRLGVQMHPGQEIHNFTLTGRNPLGQAQS-AVVINVTE 424
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPS-------IKSVIILKYNIQYRTKDASTWSQ 271
+V P+ P +L V + S+++ +W P + + I K N + ++A+
Sbjct 425 RVAPHDPTSLKVKDIN--STVVTFSWYLPGNFTKINLLCQIEICKANSKKEVRNATI--- 479
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW--SDWSEEASGITYEDRPSKA 329
+ V L P+T Y FR+RC K +W S WS+E +T E PSK
Sbjct 480 ---RGAEDSTYHVAVDKLNPYTAYTFRVRC---SSKTFWKWSRWSDEKRHLTTEATPSKG 533
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT---RWKSHLQNYTVNATK 386
P W + + + + + WK LP EANGKIL Y V+ + +S L+ + +
Sbjct 534 PDTWRE----WSSDGKNLIVYWKPLPINEANGKILSYNVSCSLNEETQSVLEIFDPQH-R 588
Query 387 LTVNLTNDRYLATLTVRNLVGKS---DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEW 443
+ L+ + Y+ ++ RN G S A + IP D +A N +++ W
Sbjct 589 AEIQLSKNDYIISVVARNSAGSSPPSKIASMEIPNDDITVE------QAVGLGNRIFLTW 642
Query 444 TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC-YLITVTPVYAD 502
Y+++WC S PC+ DW++ T + + + Y +
Sbjct 643 RHDPNMTCDYVIKWCNSSRSEPCLLDWRKVPSNSTETVIESDQFQPGVRYNFYLYGCTNQ 702
Query 503 GPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY---- 558
G SI Y+++ P P + + +++WD +PV+ GF+R Y ++
Sbjct 703 GYQLLRSIIGYVEELAPIVAPNFTVEDTSADSILVKWDDIPVEELRGFLRGYLFYFQKGE 762
Query 559 ------RTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
R++ + + + + D S ++ L T Y + + AYT G GPE +
Sbjct 763 RDTPKTRSLEPHHSDIKLKNITDISQKTLRIADLQGKTSYHLVLRAYTH--GGLGPEKSM 820
Query 609 --TTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQW 666
T + + G I AI++PV +A ++ + +L C+ KR+ IK+ +P++P+P Q+
Sbjct 821 FVVTKENSVGLIIAILIPVAVAVIVGVVTSIL-CYRKREWIKETFYPDIPNPENCKALQF 879
>sp|O70535|LIFR_RAT Leukemia inhibitory factor receptor OS=Rattus
norvegicus OX=10116 GN=Lifr PE=2 SV=1
Length=1093
Score = 145 bits (367), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 149/588 (25%), Positives = 248/588 (42%), Gaps = 61/588 (10%)
Query 114 NVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHL----ETNFTL------KSE 163
+VYG + +G PP+ P+ LSC ++ K++ C W+ GR T L T +TL KS
Sbjct 317 DVYGTVVFAGYPPDVPQKLSCETHDLKEIICSWNPGRITGLVGPRNTEYTLFESISGKSA 376
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN 223
H+F + + T ++ + A N LG+ T I + +V +
Sbjct 377 -VFHRFEELANETYWLTLKMAPDQEIHNFTL----TARNPLGQ-TESAIVINATERVALH 430
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY-RTKDASTWSQIPPEDTASTRS 282
P +L V + S+++ L+W P + I L I+ + + +
Sbjct 431 VPISLKVKDVN--STVVTLSWYLPGNFTKINLVCQIEICKANSKKEVRNVTMRGAEDSTY 488
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
V L P+T Y FR+RC E WS WS E +T E PSK P W + +
Sbjct 489 HVAVDKLNPYTIYTFRVRCSSETF-WKWSKWSNEKRYLTTEATPSKGPDTWRE----WSS 543
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWK--SHLQNYTVNATKLTVNLTNDRYLATL 400
+ + + WK LP EANGKIL Y V+ + + L K + + + Y+ ++
Sbjct 544 DGKNLIIYWKPLPINEANGKILSYNVSCSSSEETQSLSEILDPQHKAEIKVNKNDYIISV 603
Query 401 TVRNLVGK---SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
RN G S A + IP D +A N +++ W Y+++W
Sbjct 604 VARNSAGSSPPSKIASMEIPNDDITVE------QAVGIGNRIFLSWQHNPNMTCDYVIKW 657
Query 458 CVLSDKAPCITDW----QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
C S PC+ DW GTV + YL T G S Y
Sbjct 658 CNSSWSEPCLLDWIKVPSNSTGTVIESDQFQPGVRYNFYLYGCT---NQGYQLLRSTIGY 714
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY----------RTIIG 563
+++ P P + + +++WD +PV+ GF+R Y ++ R++
Sbjct 715 IEELAPIVAPNFTVEDTSADSILVKWDDIPVEELRGFLRGYLFYFQKGERDTPKTRSLET 774
Query 564 NETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF--TTPKFAQGE 617
+ + + + D S ++ L T Y + + AYT G GPE + T + + G
Sbjct 775 SHSDIKLKNITDISQKTLRIADLQGKTSYHLVLRAYTH--GGLGPEKSMFVVTKENSVGL 832
Query 618 IEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQ 665
I AI++PV +A ++ + +L C+ KR+ IK+ +P++P+P Q
Sbjct 833 IIAILIPVAVAVIVGVVTSIL-CYRKREWIKETFYPDIPNPENCKALQ 879
>sp|Q65Z14|OSMR_RAT Oncostatin-M-specific receptor subunit beta
OS=Rattus norvegicus OX=10116 GN=Osmr PE=2 SV=1
Length=962
Score = 138 bits (347), Expect = 6e-32, Method: Compositional matrix adjust.
Identities = 150/614 (24%), Positives = 259/614 (42%), Gaps = 71/614 (12%)
Query 87 SSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEW 146
++V F + A NI C + + N +G + E+PKN SC + K + C W
Sbjct 201 NNVVFLNNAGTNIN--CKAMNGTK---NTFGTVLFVSKVLEEPKNFSCETRDFKTLNCLW 255
Query 147 DGGRETHLE------TNFTLKSEWATHKFADCKAKRDTPT-SCTVDYSTVYFVNIEVWVE 199
+ G +T L ++TL ++ + + R++ T T D Y +
Sbjct 256 EPGIDTTLSWHKQRSQHYTLYESFSGRR--EVSNHRNSHTWQITEDSQETYNFTLT---- 309
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL-KYN 258
AEN L K S I+F+ ++V P PH++++ + +TW PS +L +
Sbjct 310 AENNLRK-RSVSISFNLTHRVHPKAPHDVTLKTVGATKA--HMTWKVPSRGDYTLLCQVE 366
Query 259 IQYRTKDASTWSQIPPEDTAS--TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
+Q ++ E S T +++ DL+P TEY +RC + WSDW ++
Sbjct 367 LQCE-------GEVIHEHNVSVHTSANYLFSDLEPDTEYKACVRCASANHFWKWSDWMQK 419
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK-- 374
T E PS+A W D G V L WK L +ANGKI+ Y + +
Sbjct 420 KFR-TPEAAPSEALDVWR--DVRTENGRHVVTLFWKPLLKSQANGKIISYNIVVENEANP 476
Query 375 SHLQNYTVNATKLTVNLTNDR--YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA 432
+ + Y+V A L NL+ D Y ++ N G S +++ + + + H + K
Sbjct 477 TESEQYSVRAPALGTNLSLDLHPYKIHISANNSAGASPESLVVLSS---HSGHEEVHEKT 533
Query 433 FPK-DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
N + W Y+++WC S C W+ + T + + E
Sbjct 534 IKGIKNGFNISWEPVSGDAIGYVVDWCAHSQTQRCDLQWKNVGPNITSTIITSDAFEPGV 593
Query 492 ---YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
+ I V + E + Y ++ PS P V + N L+W D Q+
Sbjct 594 RYNFRIFERSV-EENVRLVEKQRGYTQELAPSVNPGVTIHNLTPNSFSLKWQDYASDFQS 652
Query 549 GFIRNYTIFY------------RTIIGNETAV---NVDSSHTE-YTLSSLTSDTLYMVRM 592
GFI+ Y ++ RT++ +++ + +VD T+ T+ +L ++LY +
Sbjct 653 GFIKGYLVYLKSKELQCNPNWERTVLSDKSVLCKYDVDDPETKTLTVENLRPESLYEFLV 712
Query 593 AAYTDEGGKDGPEFTF---TTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKK 649
YT G GP T+ TTP + I++P+ L L+ ++ C+ K +K+
Sbjct 713 TPYTSAG--QGPNETYTKVTTPDVRSHMLLQIILPMTLGVFLS----IIVCYWKSQWVKE 766
Query 650 HIWPNVPDPSKSHI 663
+P++P+P KS I
Sbjct 767 KCYPDIPNPYKSSI 780
>sp|O70458|OSMR_MOUSE Oncostatin-M-specific receptor subunit beta
OS=Mus musculus OX=10090 GN=Osmr PE=1 SV=1
Length=971
Score = 132 bits (332), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 144/604 (24%), Positives = 247/604 (41%), Gaps = 98/604 (16%)
Query 113 QNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADC 172
+ ++G + E+PKN+SC + K + C W+ G +T L W +F +
Sbjct 221 KRIFGTVLFVSKVLEEPKNVSCETRDFKTLDCSWEPGVDTTLT--------WRKQRFQNY 272
Query 173 KAKRDTPTSCTV-DYSTVYFVNI-----EVW---VEAENALGKVTSDHINFDPVYKVKPN 223
C V +Y Y I E++ + AEN L K S +INF+ ++V P
Sbjct 273 TLCESFSKRCEVSNYRNSYTWQITEGSQEMYNFTLTAENQLRK-RSVNINFNLTHRVHPK 331
Query 224 PPHN--LSVINSEELSSILKLTWTNPSIKS--VIILKYNIQYRTKDASTWSQIPPEDTAS 279
P + L +I + + + +TW S + ++ + +QY ++ E S
Sbjct 332 APQDVTLKIIGATKAN----MTWKVHSHGNNYTLLCQVKLQY--------GEVIHEHNVS 379
Query 280 TRSS--FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
S + DL P T+Y +RC + WSDW+++ T E PS+A W ++
Sbjct 380 VHMSANYLFSDLDPDTKYKAFVRCASANHFWKWSDWTQKEFS-TPETAPSQALDVWRQV- 437
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK--SHLQNYTVNATKLTVNLTNDR 395
G R V L WK L +ANGKI+ Y + + + ++Y V A L+ NL+ D
Sbjct 438 -WSENGRRIVTLFWKPLLKSQANGKIISYNIVVENEAKPTESEHYCVWAPALSTNLSLDL 496
Query 396 --YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKY 453
Y +T N +G S +++ + +K + + W Y
Sbjct 497 QPYKIRITTNNSMGASPESLMVLSNDSGHEEVKEKTIKGI--KDAFNISWEPVSGDTMGY 554
Query 454 ILEWCVLSDKAPCITDWQQ---------------EDGTVHRTYLRGNLAESKCYLITVTP 498
+++WC S C W+ + G + + E K L+
Sbjct 555 VVDWCAHSQDQRCDLQWKNLGPNTTSTTITSDDFKPGVRYNFRIFERSVEHKARLV---- 610
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
E + Y ++ P P V N VL W D Q GFI+ Y ++
Sbjct 611 ---------EKQRGYTQELAPLVNPKVEIPYSTPNSFVLRWPDYDSDFQAGFIKGYLVYV 661
Query 559 ------------RTIIGNETAV---NVDSSHTE-YTLSSLTSDTLYMVRMAAYTDEGGKD 602
RT++ + + + +++ S T+ T+ +L ++LY + YT G
Sbjct 662 KSKEMQCNQPWERTLLPDNSVLCKYDINGSETKTLTVENLQPESLYEFFVTPYTSAG--P 719
Query 603 GPEFTFT---TPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPS 659
GP TFT TP + I++P+ L LL+ ++ C+ K +K+ +P++P+P
Sbjct 720 GPNETFTKVTTPDARSHMLLQIILPMTLCVLLS----IIVCYWKSQWVKEKCYPDIPNPY 775
Query 660 KSHI 663
KS I
Sbjct 776 KSSI 779
>sp|Q9JM58|CRLF1_MOUSE Cytokine receptor-like factor 1 OS=Mus
musculus OX=10090 GN=Crlf1 PE=1 SV=1
Length=425
Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 88/309 (28%), Positives = 137/309 (44%), Gaps = 18/309 (6%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
ISP+ P + + S+ A C + D A + W N +P E ++N + ++
Sbjct 46 ISPQDPTLLIGSSLQATCSIHG---DTPGATAEGLYWTLNGRRLPSELSRLLNTSTLALA 102
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
++ Q N++ + + G + GLPPEKP N+SC K + C W G
Sbjct 103 LANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTPGA 162
Query 151 --ETHLETNFTLKSE--WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK 206
ET L TN++LK + W + P SC + F E+WVEA N LG
Sbjct 163 HGETFLHTNYSLKYKLRWYGQDNTCEEYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGS 222
Query 207 VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN-PSIKSVII-LKYNIQYRTK 264
SD + D + V +PP ++ V L L + W + P++K + KY I+YR +
Sbjct 223 ARSDVLTLDVLDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVE 282
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC-----MKEDGKGYWSDWSEEASG 319
D+ W + D S ++S + LKP T Y ++RC G WS+WS +
Sbjct 283 DSVDWKVV---DDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAA 339
Query 320 IT-YEDRPS 327
T +RP
Sbjct 340 STPRSERPG 348
>sp|O75462|CRLF1_HUMAN Cytokine receptor-like factor 1 OS=Homo
sapiens OX=9606 GN=CRLF1 PE=1 SV=1
Length=422
Score = 123 bits (309), Expect = 9e-29, Method: Compositional matrix adjust.
Identities = 87/309 (28%), Positives = 137/309 (44%), Gaps = 18/309 (6%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
ISP+ P + + S+ A C + D A + W N +P E ++N + ++
Sbjct 43 ISPQDPTLLIGSSLLATCSVHG---DPPGATAEGLYWTLNGRRLPPELSRVLNASTLALA 99
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
++ + N++ + + G + GLPPEKP N+SC K + C W G
Sbjct 100 LANLNGSRQRSGDNLVCHARDGSILAGSCLYVGLPPEKPVNISCWSKNMKDLTCRWTPGA 159
Query 151 --ETHLETNFTLKSE--WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK 206
ET L TN++LK + W + P SC + F E+WVEA N LG
Sbjct 160 HGETFLHTNYSLKYKLRWYGQDNTCEEYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGS 219
Query 207 VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN-PSIKSVII-LKYNIQYRTK 264
SD + D + V +PP ++ V L L + W + P++K + KY I+YR +
Sbjct 220 ARSDVLTLDILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVE 279
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC-----MKEDGKGYWSDWSEEASG 319
D+ W + D S ++S + LKP T Y ++RC G WS+WS +
Sbjct 280 DSVDWKVV---DDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAA 336
Query 320 IT-YEDRPS 327
T +RP
Sbjct 337 STPRSERPG 345
>sp|Q99650|OSMR_HUMAN Oncostatin-M-specific receptor subunit beta
OS=Homo sapiens OX=9606 GN=OSMR PE=1 SV=1
Length=979
Score = 125 bits (314), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 143/590 (24%), Positives = 238/590 (40%), Gaps = 62/590 (11%)
Query 109 GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHL------ETNFTLKS 162
G + + + GI + E+PK+ SC + K + C WD G +T L ++TL
Sbjct 220 GNVSEGMKGIVLFVSKVLEEPKDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFE 279
Query 163 EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 222
++ K C K T D Y + AEN L K S +I F+ ++V
Sbjct 280 SFSGEK-KLCTHKNWCNWQITQDSQETYNFTL----IAENYLRK-RSVNILFNLTHRVYL 333
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P +++ N ++I +TW SI++ I+ + + +
Sbjct 334 MNPFSVNFENVNATNAI--MTWKVHSIRNNFTYLCQIELHGEGKMMQYNV----SIKVNG 387
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
+ + +L+P TEY+ R+RC WS+WS + + T E PS+AP W + S
Sbjct 388 EYFLSELEPATEYMARVRCADASHFWKWSEWSGQ-NFTTLEAAPSEAPDVWRIV--SLEP 444
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWK--SHLQNYTVNATKLTVNLTNDR--YLA 398
G TV L WK L ANGKIL Y V + S + +++ A + L DR Y
Sbjct 445 GNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQI 504
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWC 458
+ N VG S A+V+ I A V + + + + W V Y+++WC
Sbjct 505 CVIANNSVGASPASVIVISA--DPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWC 562
Query 459 VLSDKAPCITDWQQEDGTVHRTYLR------GNLAESKCYLITVTPVYADGPGSPESIKA 512
+ W+ T + G + + Y ++ + E
Sbjct 563 DHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIAC----LLEKKTG 618
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-----ETA 567
Y ++ PS P V + + L W + Q GFI+ Y ++ ++ E A
Sbjct 619 YSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKA 678
Query 568 VNVDSSHT-----------EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF---TTPKF 613
V D S + +L ++ Y + +T G +GP TF TTP
Sbjct 679 VLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAG--EGPSATFTKVTTPD- 735
Query 614 AQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHI 663
E ++++ + L + LL ++ C+ K IK+ +P++PDP KS I
Sbjct 736 ---EHSSMLIHILLPMVFCVLLIMVMCYLKSQWIKETCYPDIPDPYKSSI 782
>sp|P48356|LEPR_MOUSE Leptin receptor OS=Mus musculus OX=10090
GN=Lepr PE=1 SV=1
Length=1162
Score = 107 bits (267), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 117/494 (24%), Positives = 204/494 (41%), Gaps = 58/494 (12%)
Query 60 VNANYIVWKTNHF-TIPKEQYTIINRTASSVTFTDIAS--------LNIQLTCNILTFGQ 110
+++ IVW N IP+ QY+I++ S VTF+++ + + CN
Sbjct 359 ISSKQIVWWRNLAEKIPEIQYSIVSDRVSKVTFSNLKATRPRGKFTYDAVYCCNEQACHH 418
Query 111 LEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHL-----ETNFTLKSEWA 165
+Y I + + E L+ KM C W L + + +S +
Sbjct 419 RYAELYVIDVNINISCETDGYLT-------KMTCRWSPSTIQSLVGSTVQLRYHRRSLYC 471
Query 166 --------THKFADCKAKRDTPTSCTVDYSTVYFVN-IEVWVEAENALGKVTSDHINFDP 216
T + +C +RD C + ++ ++ +W+ ++LG + S P
Sbjct 472 PDSPSIHPTSEPKNCVLQRDGFYECV--FQPIFLLSGYTMWIRINHSLGSLDSPPTCVLP 529
Query 217 VYKVKPNPPHNLSV---INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST----- 268
VKP PP N+ +N+ +LK++W P + + N+Q++ + +
Sbjct 530 DSVVKPLPPSNVKAEITVNT----GLLKVSWEKP-----VFPENNLQFQIRYGLSGKEIQ 580
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR-PS 327
W D S +S V DL YV ++RC + DG GYWS+WS A + + + P
Sbjct 581 WKTHEVFDAKSKSASLLVSDL--CAVYVVQVRCRRLDGLGYWSNWSSPAYTLVMDVKVPM 638
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT-LTRWKSHLQNYTVNATK 386
+ P FW K+D T+ R V L+WK L ++ + Y V T N T
Sbjct 639 RGPEFWRKMDGDVTKKERNVTLLWKPLTKNDSLCSVRRYVVKHRTAHNGTWSEDVGNRTN 698
Query 387 LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWT- 444
LT T + T+ N +G S + V L A+P + + + WT
Sbjct 699 LTFLWTEPAHTVTVLAVNSLGASLVNFNLTFSWPMSKVSAVESLSAYPLSSSCVILSWTL 758
Query 445 TPRE-SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADG 503
+P + S+ ++EW +L++ W + V + Y+ N + Y ++ PV+ +G
Sbjct 759 SPDDYSLLYLVIEWKILNEDDG--MKWLRIPSNVKKFYIHDNFIPIEKYQFSLYPVFMEG 816
Query 504 PGSPESIKAYLKQA 517
G P+ I + K A
Sbjct 817 VGKPKIINGFTKDA 830
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 30/119 (25%), Positives = 58/119 (49%), Gaps = 7/119 (6%)
Query 196 VWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
+++E +A S ++ P+ VKP+PP L + +++ + LK++W S +
Sbjct 210 MYLEITSAGVSFQSPLMSLQPMLVVKPDPPLGLHMEVTDDGN--LKISW-----DSQTMA 262
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
+ +QY+ K + + + +S V + P + Y ++R + DG G WSDWS
Sbjct 263 PFPLQYQVKYLENSTIVREAAEIVSATSLLVDSVLPGSSYEVQVRSKRLDGSGVWSDWS 321
>sp|O02671|LEPR_PIG Leptin receptor OS=Sus scrofa OX=9823 GN=LEPR
PE=2 SV=3
Length=1165
Score = 103 bits (256), Expect = 5e-21, Method: Compositional matrix adjust.
Identities = 117/519 (23%), Positives = 215/519 (41%), Gaps = 65/519 (13%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHF-TIPKEQYTIINRTASSVTF 91
P + + SN + C+ K + V++ IVW N IP+ QY ++ S VTF
Sbjct 337 PPKILTSVGSNISFHCIYKNENKI---VSSKKIVWWMNLAEKIPQSQYDVVGDHVSKVTF 393
Query 92 TDIAS--------LNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
++ + + CN +Y I + + E L+ KM
Sbjct 394 PNMNATKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLT-------KMT 446
Query 144 CEWDGGR-----ETHLETNFTLKSEWAT-----HKFA---DCKAKRDTPTSCTVDYSTVY 190
C W + L+ + S + + H + DC+ +RD C + ++
Sbjct 447 CRWSTNAIQSLVGSTLQLRYHRSSLYCSDVPSVHPISEPKDCQLQRDGFYECI--FQPIF 504
Query 191 FVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
++ +W+ + LG + S P VKP PP ++ + ++ +LK++W P
Sbjct 505 LLSGYTMWIRINHPLGSLDSPPTCVIPDSVVKPLPPSSVKAEITAKIG-LLKISWEKP-- 561
Query 250 KSVIILKYNIQYRTKDAST-----WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ + N+Q++ + + W DT +S V DL Y ++RC +
Sbjct 562 ---VFPENNLQFQIRYGLSGKEVQWKIYEVYDTKLKSTSLPVPDL--CAVYAVQVRCKRL 616
Query 305 DGKGYWSDWSEEASGITYEDR-PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
DG GYWS+WS A + + + P + P FW I+ T+ R + L+WK L ++ +
Sbjct 617 DGLGYWSNWSTPAYTVVTDVKVPIRGPEFWRIINEDATKKERNITLLWKPLMKNDSLCSV 676
Query 364 LDYEVTLTRWKSHLQNYTV------NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
Y V K H + N TKLT T + T+ N +G S A
Sbjct 677 RSYVV-----KHHTSRHGTWSEDVGNHTKLTFLWTEQAHSVTVLAVNSIGASSANFNLTF 731
Query 418 ACDFQATHPVMDLKAFP-KDNMLWVEW-TTPRE-SVKKYILEWCVLSDKAPCITDWQQED 474
+ + V L A+P + + + W +P + ++ +ILEW +L++ W +
Sbjct 732 SWPMSKVNIVQSLSAYPLNSSCVGLSWLLSPSDYNLMYFILEWKILNEDHE--IKWLRIP 789
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
+V + Y+ + + Y ++ P++ +G G P+ I ++
Sbjct 790 SSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSF 828
Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 28/104 (27%), Positives = 57/104 (55%), Gaps = 8/104 (8%)
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK-DASTWS 270
++ P+ VKP+PP L + ++ + LK++W++P++ + + +QY+ K ++ +
Sbjct 227 MSVQPINVVKPDPPLGLHMEITD--TGNLKISWSSPTL-----VPFQLQYQVKYSENSTT 279
Query 271 QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
+ D + +S V + P + Y ++R + DG G WSDWS
Sbjct 280 NMREADEIVSDTSLLVDSVLPGSSYEVQVRGKRLDGPGIWSDWS 323
>sp|Q62959|LEPR_RAT Leptin receptor OS=Rattus norvegicus OX=10116
GN=Lepr PE=1 SV=1
Length=1162
Score = 102 bits (253), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 120/515 (23%), Positives = 208/515 (40%), Gaps = 53/515 (10%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHF-TIPKEQYTIINRTASSVTF 91
P + + SN + C+ K + +++ IVW N IP+ QY ++ S VTF
Sbjct 335 PPKILTSVGSNASFCCIYKNENQT---ISSKQIVWWMNLAEKIPETQYNTVSDHISKVTF 391
Query 92 TDIAS--------LNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
+++ + + CN +Y I + + E L+ KM
Sbjct 392 SNLKATRPRGKFTYDAVYCCNEQACHHRYAELYVIDVNINISCETDGYLT-------KMT 444
Query 144 CEWDGGRETHL-----ETNFTLKSEWA--------THKFADCKAKRDTPTSCTVDYSTVY 190
C W L + + +S + T + +C + D C + ++
Sbjct 445 CRWSPSTIQSLVGSTVQLRYHRRSLYCPDNPSIRPTSELKNCVLQTDGFYECV--FQPIF 502
Query 191 FVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV---INSEELSSILKLTWTN 246
++ +W+ ++LG + S P VKP PP N+ IN+ +LK++W
Sbjct 503 LLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVKAEITINT----GLLKVSWEK 558
Query 247 PSIKSVIILKYNIQYRTKDAST-WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P L++ I+Y W D S +S V DL YV ++RC + D
Sbjct 559 PVFPENN-LQFQIRYGLNGKEIQWKTHEVFDAKSKSASLPVSDL--CAVYVVQVRCRRLD 615
Query 306 GKGYWSDWSEEASGITYEDR-PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
G GYWS+WS A + + + P + P FW +D T+ R V L+WK L ++ +
Sbjct 616 GLGYWSNWSSPAYTLVMDVKVPMRGPEFWRIMDGDITKKERNVTLLWKPLMKNDSLCSVR 675
Query 365 DYEVTLTRWKSHLQNYTV-NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA 423
Y V + + V N T LT + T+ N +G S +
Sbjct 676 RYVVKHRTAHNGTWSQDVGNQTNLTFLWAESAHTVTVLAINSIGASLVNFNLTFSWPMSK 735
Query 424 THPVMDLKAFP-KDNMLWVEWT-TPRE-SVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ V L A+P + + + WT +P + S+ ++EW L+D W + V++
Sbjct 736 VNAVQSLSAYPLSSSCVILSWTLSPNDYSLLYLVIEWKNLNDDDG--MKWLRIPSNVNKY 793
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
Y+ N + Y ++ PV+ +G G P+ I + K
Sbjct 794 YIHDNFIPIEKYQFSLYPVFMEGVGKPKIINGFTK 828
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 34/119 (29%), Positives = 62/119 (52%), Gaps = 7/119 (6%)
Query 196 VWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
+++E +A S ++ P+ VKP+PP L + +++ + LK++W + K+ L
Sbjct 210 MYLEITSAGVSFQSPLMSLQPMLVVKPDPPLGLRMEVTDDGN--LKISW-DSQTKAPFPL 266
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
+Y ++Y + ST + E + T S V + P + Y ++R + DG G WSDWS
Sbjct 267 QYQVKYL--ENSTIVREAAEIVSDT--SLLVDSVLPGSSYEVQVRSKRLDGSGVWSDWS 321
>sp|Q9MYL0|LEPR_MACMU Leptin receptor OS=Macaca mulatta OX=9544
GN=LEPR PE=2 SV=2
Length=1163
Score = 94.7 bits (234), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 115/516 (22%), Positives = 202/516 (39%), Gaps = 59/516 (11%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHF-TIPKEQYTIINRTASSVTF 91
P + + SN + C+ K + V++ IVW N IP+ QY +++ S VTF
Sbjct 335 PPKILTSVGSNVSFHCIYKNENKI---VSSKKIVWWMNLAEKIPQSQYDVVSDHVSKVTF 391
Query 92 TDIA--------SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
++ + + CN +Y I + + E +L+ KM
Sbjct 392 FNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGHLT-------KMT 444
Query 144 CEWD-------GGRETHLETN------FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY 190
C W G L F + S K DC + D C + ++
Sbjct 445 CRWSTNTIQSLAGSTLQLRYRRSSLYCFDIPSIHPISKPKDCYLQSDGFYECV--FQPIF 502
Query 191 FVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI--LKLTWTNP 247
++ +W+ + LG + S P VKP PP S + +E + +I LK++W P
Sbjct 503 LLSGYTMWIRINHPLGSLDSPPTCVLPDSVVKPLPP---SSVKAEIIKNIGLLKISWEKP 559
Query 248 SIKSVIILKYNIQYRTKDAST-----WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
+ + N+Q++ + + W D S S V D Y ++RC
Sbjct 560 -----VFPENNLQFQIRYGLSGKEIQWKMYDVYDAKSKSVSLPVPDF--CAVYAVQVRCK 612
Query 303 KEDGKGYWSDWSEEASGITYEDR-PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ DG G WS+WS A + + + P + P FW I+ + + V L+WK L E+
Sbjct 613 RSDGLGLWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNESLC 672
Query 362 KILDYEVT-LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
+ Y + T N TK T T + T+ N +G S A +
Sbjct 673 SVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSIGASVANFNLTFSWP 732
Query 421 FQATHPVMDLKAFPKD-NMLWVEWTTPRESVK--KYILEWCVLSDKAPCITDWQQEDGTV 477
+ V L A+P + + + + W K +I+EW L++ W + +V
Sbjct 733 MSKVNIVQSLSAYPLNSSCVILSWILSPSDYKLMYFIIEWKNLNEDGE--IKWLRISSSV 790
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
+ Y+ + + Y ++ P++ +G G P+ I ++
Sbjct 791 KKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSF 826
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 33/116 (28%), Positives = 58/116 (50%), Gaps = 13/116 (11%)
Query 206 KVTSDHINFD-------PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
K+TS + F P+ VKP+PP L + +++ + LK++W++P + L+Y
Sbjct 212 KITSGGVIFQSPLMSVQPINMVKPDPPLGLRMEITDDGN--LKISWSSPPLVP-FPLQYE 268
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
++Y + I D + +S V + P + Y ++R + DG G WSDWS
Sbjct 269 VKYSENSTTV---IREADKIVSATSLLVDGILPGSSYEVQVRGKRLDGPGIWSDWS 321
>sp|P48357|LEPR_HUMAN Leptin receptor OS=Homo sapiens OX=9606
GN=LEPR PE=1 SV=2
Length=1165
Score = 94.0 bits (232), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 113/514 (22%), Positives = 206/514 (40%), Gaps = 55/514 (11%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHF-TIPKEQYTIINRTASSVTF 91
P + + SN + C+ K++ V + IVW N IP+ QY +++ S VTF
Sbjct 337 PPKILTSVGSNVSFHCIYKKENKI---VPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTF 393
Query 92 TDIA--------SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
++ + + CN +Y I + + E L+ KM
Sbjct 394 FNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLT-------KMT 446
Query 144 CEWDGG-----RETHLETNFTLKSEWAT-----HKFA---DCKAKRDTPTSCTVDYSTVY 190
C W E+ L+ + S + + H + DC + D C + ++
Sbjct 447 CRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECI--FQPIF 504
Query 191 FVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
++ +W+ ++LG + S P VKP PP ++ + + +LK++W P
Sbjct 505 LLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIG-LLKISWEKP-- 561
Query 250 KSVIILKYNIQYRTKDAST-----WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ + N+Q++ + + W D S S V DL Y ++RC +
Sbjct 562 ---VFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDL--CAVYAVQVRCKRL 616
Query 305 DGKGYWSDWSEEASGITYEDR-PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
DG GYWS+WS A + + + P + P FW I+ + + V L+WK L ++ +
Sbjct 617 DGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDSLCSV 676
Query 364 LDYEVT-LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
Y + T N TK T T + T+ N +G S A +
Sbjct 677 QRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSIGASVANFNLTFSWPMS 736
Query 423 ATHPVMDLKAFPKD-NMLWVEWTTPRESVK--KYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ V L A+P + + + V W K +I+EW L++ W + +V +
Sbjct 737 KVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNEDGE--IKWLRISSSVKK 794
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
Y+ + + Y ++ P++ +G G P+ I ++
Sbjct 795 YYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSF 828
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 33/117 (28%), Positives = 61/117 (52%), Gaps = 15/117 (13%)
Query 206 KVTSDHINFD-------PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
K+TS + F P+ VKP+PP L + +++ + LK++W++P + + +
Sbjct 214 KITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGN--LKISWSSPPL-----VPFP 266
Query 259 IQYRTKDASTWSQIPPE-DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
+QY+ K + + + E D + +S V + P + Y ++R + DG G WSDWS
Sbjct 267 LQYQVKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWS 323
>sp|O46561|PRLR_SHEEP Prolactin receptor OS=Ovis aries OX=9940
GN=PRLR PE=2 SV=1
Length=581
Score = 85.9 bits (211), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 65/221 (29%), Positives = 107/221 (48%), Gaps = 21/221 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL----KSEWATHKFADCKAKRDTPT 180
PPEKPK + C + C W+ G + L TN+TL + E H+ D K P
Sbjct 27 PPEKPKLIKCRSPGKETFTCWWEPGADGGLPTNYTLTYRKEGETLIHECPDYKT--GGPN 84
Query 181 SC--TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEEL 236
SC + Y++++ + + + V A N +G +SD + D Y V+P PP NL+ + + E+
Sbjct 85 SCYFSKKYTSIWKMYV-ITVSAINQMGISSSDPLYVDVTYIVEPEPPVNLTLELKHPEDR 143
Query 237 SSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
L + W+ P++ V ++Y I+ + + A+ W A + + +L P
Sbjct 144 KPYLWIKWSPPTLTDVKSGWFSIQYEIRLKPEKATDWET----HFAPKLTQLKIFNLYPG 199
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
+Y+ +IRC + GYWS+WS E+ D P K S W
Sbjct 200 QKYLVQIRCKPD--HGYWSEWSPESFIQIPNDFPVKDTSMW 238
>sp|Q28172|PRLR_BOVIN Prolactin receptor OS=Bos taurus OX=9913
GN=PRLR PE=1 SV=1
Length=581
Score = 84.7 bits (208), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 64/221 (29%), Positives = 108/221 (49%), Gaps = 21/221 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL----KSEWATHKFADCKAKRDTPT 180
PPEKPK + C + C W+ G + L TN+TL + E H+ D K P
Sbjct 27 PPEKPKLVKCRSPGKETFTCWWEPGADGGLPTNYTLTYHKEGETLIHECPDYKT--GGPN 84
Query 181 SC--TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEEL 236
SC + +++++ + + + V A N +G +SD + Y V+P PP NL+ + + E+
Sbjct 85 SCYFSKKHTSIWKMYV-ITVNAINQMGISSSDPLYVHVTYIVEPEPPANLTLELKHPEDR 143
Query 237 SSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
L + W+ P++ V I++Y I+ + + A+ W ++ + +L P
Sbjct 144 KPYLWIKWSPPTMTDVKSGWFIIQYEIRLKPEKATDWET----HFTLKQTQLKIFNLYPG 199
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
+Y+ +IRC + GYWS+WS E+S D P K S W
Sbjct 200 QKYLVQIRCKPD--HGYWSEWSPESSIQIPNDFPVKDTSMW 238
>sp|P05710|PRLR_RAT Prolactin receptor OS=Rattus norvegicus OX=10116
GN=Prlr PE=1 SV=2
Length=610
Score = 84.7 bits (208), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 64/217 (29%), Positives = 109/217 (50%), Gaps = 22/217 (10%)
Query 115 VYGITIISGL-PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL----KSEWATHKF 169
V I+++ G PP KP+ C + + C W+ G + L TN++L + E T++
Sbjct 11 VLNISLLKGQSPPGKPEIHKCRSPDKETFTCWWNPGTDGGLPTNYSLTYSKEGEKTTYEC 70
Query 170 ADCKAKRDTPTSC--TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHN 227
D K P SC + Y++++ + I + V A N +G +SD + D Y V+P PP N
Sbjct 71 PDYKTS--GPNSCFFSKQYTSIWKIYI-ITVNATNQMGSSSSDPLYVDVTYIVEPEPPRN 127
Query 228 LS--VINSEELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTR 281
L+ V ++ + L + W+ P+I V ++Y I+ + ++A W +
Sbjct 128 LTLEVKQLKDKKTYLWVKWSPPTITDVKTGWFTMEYEIRLKPEEAEEWEI----HFTGHQ 183
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+ F V DL P +Y+ + RC + GYWS WS+E+S
Sbjct 184 TQFKVFDLYPGQKYLVQTRCKPD--HGYWSRWSQESS 218
>sp|Q08501|PRLR_MOUSE Prolactin receptor OS=Mus musculus OX=10090
GN=Prlr PE=1 SV=1
Length=608
Score = 84.3 bits (207), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 64/217 (29%), Positives = 108/217 (50%), Gaps = 22/217 (10%)
Query 115 VYGITIISGL-PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL----KSEWATHKF 169
V I++++G PP KP+ C + + C W+ G + L TN++L + E T++
Sbjct 11 VLSISLLNGQSPPGKPEIHKCRSPDKETFTCWWNPGSDGGLPTNYSLTYSKEGEKNTYEC 70
Query 170 ADCKAKRDTPTSC--TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHN 227
D K P SC + Y++++ + I + V A N +G TSD + D Y V+P PP N
Sbjct 71 PDYKTS--GPNSCFFSKQYTSIWKIYI-ITVNATNEMGSSTSDPLYVDVTYIVEPEPPRN 127
Query 228 LS--VINSEELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTR 281
L+ V ++ + L + W P+I V ++Y I+ ++++A W +
Sbjct 128 LTLEVKQLKDKKTYLWVKWLPPTITDVKTGWFTMEYEIRLKSEEADEWEI----HFTGHQ 183
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+ F V DL P +Y+ + RC + GYWS W +E S
Sbjct 184 TQFKVFDLYPGQKYLVQTRCKPD--HGYWSRWGQEKS 218
>sp|Q6JTA8|PRLR_PIG Prolactin receptor OS=Sus scrofa OX=9823 GN=PRLR
PE=2 SV=2
Length=625
Score = 82.8 bits (203), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 60/206 (29%), Positives = 101/206 (49%), Gaps = 21/206 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL----KSEWATHKFADCKAKRDTPT 180
PP KP+ C E + C W G + L TN+TL + E TH+ D K P
Sbjct 27 PPGKPEIFKCRSPEKETFTCWWKPGADGGLPTNYTLTYHKEGETFTHECPDYKT--GGPN 84
Query 181 SCTVD--YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEEL 236
SC + +++++ + I + V A N +G +SD D Y V+P+PP NL+ + E+
Sbjct 85 SCYFNKKHTSIWTIYI-ITVNATNQMGSSSSDPRYVDVTYIVEPDPPVNLTLELKKPEDQ 143
Query 237 SSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
L + W P++ V + L+Y I+ + + + W A ++ F + L P
Sbjct 144 KPYLWIKWLPPTLVDVRSGWLTLQYEIRLQPEKTAEWET----HFAGQQTQFKILSLYPG 199
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEAS 318
+Y+ ++RC + G+WS+WS E+S
Sbjct 200 QKYLVQVRCKPD--HGFWSEWSPESS 223
>sp|P14787|PRLR_RABIT Prolactin receptor OS=Oryctolagus cuniculus
OX=9986 GN=PRLR PE=1 SV=1
Length=616
Score = 81.6 bits (200), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 62/206 (30%), Positives = 100/206 (49%), Gaps = 21/206 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL----KSEWATHKFADCKAKRDTPT 180
PP KP C E + C W G + L TN+TL + E TH+ D K P
Sbjct 27 PPGKPFIFKCRSPEKETFTCWWRPGADGGLPTNYTLTYHKEGETITHECPDYKT--GGPN 84
Query 181 SC--TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEEL 236
SC + +++++ + I + V A N +G SD D Y V+P+PP NL+ V + E+
Sbjct 85 SCYFSKKHTSIWTIYI-ITVNATNQMGSSVSDPRYVDVTYIVEPDPPVNLTLEVKHPEDR 143
Query 237 SSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
L + W P++ V + L+Y I+ + + A+ W A ++ F + L P
Sbjct 144 KPYLWVKWLPPTLVDVRSGWLTLQYEIRLKPEKAAEWET----HFAGQQTQFKILSLYPG 199
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEAS 318
+Y+ ++RC + G+WS WS E+S
Sbjct 200 QKYLVQVRCKPD--HGFWSVWSPESS 223
>sp|Q28235|PRLR_CEREL Prolactin receptor OS=Cervus elaphus OX=9860
GN=PRLR PE=2 SV=1
Length=581
Score = 80.9 bits (198), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 60/221 (27%), Positives = 107/221 (48%), Gaps = 21/221 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL----KSEWATHKFADCKAKRDTPT 180
PP KPK + C + C W+ G + L TN+TL + E H+ D K P
Sbjct 27 PPGKPKIIKCRSPGKETFTCWWEPGSDGGLPTNYTLTYHKEGETLIHECPDYKT--GGPN 84
Query 181 SC--TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEEL 236
+C + +++++ + + + V A N +G +SD + D Y V+P PP NL+ + + E+
Sbjct 85 TCYFSKKHTSIWKIYV-ITVNAINQMGVSSSDPLYVDVTYIVEPEPPANLTLELKHPEDR 143
Query 237 SSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
L + W P++ V +++Y I+ + + A+ W A+ ++ + L P
Sbjct 144 KPYLWIKWFPPTLTDVKSGWFMIQYEIRLKPETAADWEI----HFAAKQTQLKIFSLYPG 199
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
+Y+ ++RC + GYWS+WS E+S D P + W
Sbjct 200 QKYLVQVRCKPD--HGYWSEWSPESSIQIPNDFPVNDTTVW 238
>sp|Q04594|PRLR_CHICK Prolactin receptor OS=Gallus gallus OX=9031
GN=PRLR PE=2 SV=1
Length=831
Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 63/209 (30%), Positives = 98/209 (47%), Gaps = 15/209 (7%)
Query 118 ITIISGL-PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFT-LKSEWATHKFADCKAK 175
I I SG PPEKP + C E + C W G + TN+T L S+ + +C
Sbjct 222 ILIPSGQSPPEKPTIIKCRSPEKETFTCWWKPGLDGGHPTNYTLLYSKEGEEQVYECPDY 281
Query 176 RDT-PTSCTVDYSTVYFVNI-EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS 233
R P SC D F I + V A N +G +SD D Y V+P+PP N+++
Sbjct 282 RTAGPNSCYFDKKHTSFWTIYNITVRATNEMGSNSSDPHYVDVTYIVQPDPPVNVTLELK 341
Query 234 EELSS--ILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
+ ++ L LTW+ P + V + L+Y ++ + ++ W I ++ + +
Sbjct 342 KPINRKPYLVLTWSPPPLADVRSGWLTLEYELRLKPEEGEEWETI----FVGQQTQYKMF 397
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
L P +Y+ +I C K D G WS+WS E
Sbjct 398 SLNPGKKYIIQIHC-KPDHHGSWSEWSSE 425
Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 59/231 (26%), Positives = 103/231 (45%), Gaps = 25/231 (11%)
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH 153
I+S+ I L + T G Q+ P KPK + C E + C W G +
Sbjct 6 ISSVQIILFLPLTTVGLAGQSF----------PGKPKIIRCRSLEKETFSCWWKPGSDGG 55
Query 154 LETNFTL-KSEWATHKFADCKAKRDT-PTSCTVDYS-TVYFVNIEVWVEAENALGKVTSD 210
L TN+TL S+ + + +C R + P SC + + T + + V A N +G +SD
Sbjct 56 LPTNYTLFYSKDSEEEIYECPDYRTSGPNSCYFNKNHTSPWTTFNITVTATNEIGSNSSD 115
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKL--TWTNPSI---KSVIILKYNIQYRTKD 265
D V+P P NL+ + ++ ++I+ L W+ P + S + Y ++ + ++
Sbjct 116 PQYVDVTSIVQPGSPVNLT-LETKRSANIMYLWAKWSPPLLADASSNHLYHYELRIKPEE 174
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
W I + ++ + L YV ++RC + G+ WS+WS E
Sbjct 175 KEEWETI----SVGVQTQCKINRLNAGMRYVVQVRCTLDPGE--WSEWSSE 219
>sp|O70394|I27RA_MOUSE Interleukin-27 receptor subunit alpha OS=Mus
musculus OX=10090 GN=Il27ra PE=1 SV=2
Length=623
Score = 79.7 bits (195), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 116/507 (23%), Positives = 188/507 (37%), Gaps = 50/507 (10%)
Query 219 KVKPNPPHNLSVIN-SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
++KP+ P S ++ SEE + + W P +L +Y+ A TW+++ P+
Sbjct 120 QMKPDTPQIFSQVDISEEATLEATVQWAPPVWPPQKVLICQFRYKECQAETWTRLEPQLK 179
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
+ +Q+L+P T Y RC E+G W E +S ++++ W
Sbjct 180 TDGLTPVEMQNLEPGTCYQVSGRCQVENGY----PWGEWSSPLSFQTPFLDPEDVWVSGT 235
Query 338 PSHTQGYRTVQLVWKTLPP--------FEANGKILDYEVTLTRWKSHLQNYTVNATKLTV 389
T G R LVWK P + G I + + KS + + A
Sbjct 236 VCETSGKRAALLVWKDPRPCVQVTYTVWFGAGDITTTQEEVPCCKSPVPAWMEWAVVSPG 295
Query 390 NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES 449
N T+ L++ L +S CD V P + W + T R+
Sbjct 296 NSTSWVPPTNLSLVCLAPESAP-------CDVG----VSSADGSPGIKVTWKQGT--RKP 342
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES 509
++ Y+++W D + +W + T L G Y ITVT VY+ G + S
Sbjct 343 LE-YVVDWAQDGDSLDKL-NWTRLPPGNLSTLLPGEFKGGVPYRITVTAVYSGGLAAAPS 400
Query 510 IKAYLKQAPPSKGPTV-RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV 568
+ + ++ P GP V R V+ W ++P G +YT ++ +
Sbjct 401 VWGFREELVPLAGPAVWRLPDDPPGTPVVAWGEVPRHQLRGQATHYTFCIQSRGLSTVCR 460
Query 569 NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLA 628
NV S TL +L + + + G GP + P I +P L+
Sbjct 461 NVSSQTQTATLPNLHLGSFKLWVTVSTVAGQGPPGPNLSLHLP---DNRIRWKALPWFLS 517
Query 629 FLLTTLLGVLF------CFNKRDLIKKH------IWPNVPDPSKSHIAQWSPHTPPRHNF 676
L+G C R L +H IW VPDP+ S+ Q P
Sbjct 518 LWGLLLMGCGLSLASTRCLQARCLHWRHKLLPQWIWERVPDPANSNSGQ------PYIKE 571
Query 677 NSKDQMYSDGNFTDVSVVEIEANDKKP 703
S Q DG +V VE++ + P
Sbjct 572 VSLPQPPKDGPILEVEEVELQPVVESP 598
>sp|Q91094|PRLR_MELGA Prolactin receptor OS=Meleagris gallopavo
OX=9103 GN=PRLR PE=2 SV=1
Length=831
Score = 79.7 bits (195), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 61/209 (29%), Positives = 98/209 (47%), Gaps = 15/209 (7%)
Query 118 ITIISGL-PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL-KSEWATHKFADCKAK 175
I I GL PPEKP C E + C W G + TN+TL S+ + +C
Sbjct 222 ILISGGLSPPEKPTITKCRSPEKETFTCWWKPGLDGGHPTNYTLLYSKEGEEQVYECPDY 281
Query 176 RDT-PTSCTVDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS 233
R P SC D T ++ + V+A N +G +SD D Y V+P+PP N+++
Sbjct 282 RTAGPNSCYFDKKHTSFWTVYNITVKATNEMGSNSSDPHYVDVTYIVQPDPPANVTLELK 341
Query 234 EELSS--ILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
+ ++ L LTW+ P + V + L Y ++ + ++ W + ++ + +
Sbjct 342 KPINRKPYLMLTWSPPPLADVRSGWLTLDYELRLKPEEGEEWETV----FVGQQTQYKMF 397
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
L P +Y+ +I C K D G WS+WS E
Sbjct 398 SLNPGKKYIVQIHC-KPDHHGSWSEWSSE 425
Score = 67.4 bits (163), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 63/247 (26%), Positives = 112/247 (45%), Gaps = 30/247 (12%)
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH 153
I+S+ I L + T G Q+ P KPK + C E + C W G +
Sbjct 6 ISSVQIILLLPLTTVGLTSQSF----------PGKPKIIRCRSLEKETFSCWWKPGSDGG 55
Query 154 LETNFTL-KSEWATHKFADCKAKRDT-PTSCTVDYS-TVYFVNIEVWVEAENALGKVTSD 210
L TN+TL S+ + K +C R + P SC + + T + + V A N +G +SD
Sbjct 56 LPTNYTLFYSKDSEEKIYECPDYRTSGPNSCYFNRNYTNSWTTYNITVTATNEIGSNSSD 115
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKL--TWTNPSI---KSVIILKYNIQYRTKD 265
D V+P P NL+ + ++ ++I+ L W+ P + S + Y ++ + ++
Sbjct 116 PQYVDVTSIVQPGSPVNLT-LETQRYANIMYLWAKWSPPLLADASSNHLYHYELRLKPEE 174
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE-----ASGI 320
W +P ++ + L YV ++RCM + G+ WS+WS E + G+
Sbjct 175 KEEWETVP----VGVQTQCKINRLNAGMRYVVQVRCMLDPGE--WSEWSSERRILISGGL 228
Query 321 TYEDRPS 327
+ ++P+
Sbjct 229 SPPEKPT 235
>sp|Q90374|PRLR_COLLI Prolactin receptor OS=Columba livia OX=8932
GN=PRLR PE=2 SV=1
Length=830
Score = 78.6 bits (192), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 70/247 (28%), Positives = 111/247 (45%), Gaps = 24/247 (10%)
Query 82 INRTASSVTFTDIASLNIQLTCNILTFGQLEQ--NVYGITIISG-LPPEKPKNLSCIVNE 138
+NR + V + +Q+ C +L G+ + + I I +G PPEKP + C E
Sbjct 192 VNRLQAGVKYV------VQVRC-VLDIGEWSEWSSERHIHIPNGESPPEKPTIIKCRSPE 244
Query 139 GKKMRCEWDGGRETHLETNFT-LKSEWATHKFADC-KAKRDTPTSCTVDYSTVYFVNI-E 195
+ C W G + TN+T L S+ + +C K P SC D F I
Sbjct 245 KETFTCWWKPGSDGGHPTNYTLLYSKEGEERVYECPDYKTAGPNSCYFDKKHTSFWTIYN 304
Query 196 VWVEAENALGKVTSDHINFDPVYKVKPNPPHN--LSVINSEELSSILKLTWTNPSIKSV- 252
+ V+A N +G SD + D Y V+ +PP N L + + L LTW+ P + V
Sbjct 305 ITVKATNEIGSNVSDPLYVDVTYIVQTDPPVNVTLELKKTVNRKPYLVLTWSPPPLADVR 364
Query 253 ---IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ L Y ++ + ++A W I ++ + + L P +Y+ +I C K D G
Sbjct 365 SGWLTLDYELRLKPEEAEEWETI----FVGQQTHYKMFSLNPGKKYIVQIHC-KPDHHGS 419
Query 310 WSDWSEE 316
WS+WS E
Sbjct 420 WSEWSLE 426
Score = 66.6 bits (161), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 92/199 (46%), Gaps = 14/199 (7%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL-KSEWATHKFADC-KAKRDTPTSCT 183
P KPK + C E + C W G + L TN+TL S+ + K +C P SC
Sbjct 28 PGKPKIIRCRSLEKETFSCWWKPGSDGGLPTNYTLFYSKDSEEKIYECPDYGMSGPNSCY 87
Query 184 VDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
D + T + + V A N +G +SD D V+P+ P NLS+ S+ L
Sbjct 88 FDKNHTNPWTTYNITVMAMNEIGSNSSDPQYVDVTSIVQPDAPVNLSLETKTSASTTYLL 147
Query 243 T-WTNPSIKSVI----ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
W+ P + V + +Y ++ + ++ W + + ++ + V L+ +YV
Sbjct 148 AKWSPPPLADVTSNSHVYRYELRLKPEEKEEWETV----SVGVQTQYKVNRLQAGVKYVV 203
Query 298 RIRCMKEDGKGYWSDWSEE 316
++RC+ + G+ WS+WS E
Sbjct 204 QVRCVLDIGE--WSEWSSE 220
>sp|Q8AV58|SDK1_CHICK Protein sidekick-1 OS=Gallus gallus OX=9031
GN=SDK1 PE=1 SV=1
Length=2169
Score = 79.0 bits (193), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 137/575 (24%), Positives = 224/575 (39%), Gaps = 90/575 (16%)
Query 115 VYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA 174
V G+ +P P+N+S ++ W E+ E N + +K D +
Sbjct 1218 VVGVRTRESVPSAPPENVSAEAVSSTQILLTWSAVPES--EQNGLILGYKILYKAKDLDS 1275
Query 175 K------RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK-----PN 223
+ R T + +V E+ V A +G D + PV + P
Sbjct 1276 EPRSQTVRGNHTQSCLLSGLRKYVLYEIRVLAFTRIG----DGVPSSPVLTERTKDDAPG 1331
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP L V L+S+ ++ W P + IIL Y I YR +S ++ + ST
Sbjct 1332 PPIRL-VFPEVRLTSV-RIVWQPPEEPNGIILGYQIAYRLASSSP-NKFTTVEVGSTVRQ 1388
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE--EASGITYEDRPSKAPSFWYKIDPSHT 341
FT DL P + Y+FR G W E EA+ IT E R AP P
Sbjct 1389 FTATDLTPESAYIFRTSAKTRQG------WGEPLEATVITTEKRERPAPPQQLTT-PQSD 1441
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTR-----WKSHLQNYTVNATKLTVNLTN--D 394
R++QL W +P + + I + V + W+++ + + AT + N
Sbjct 1442 VSSRSLQLHW--VPGSDGSSPIRYFTVQVRELPNGDWQTYSSSISHEATSCIIESLNPFT 1499
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNML---------WVEWTT 445
Y + N +G SD + T +A + D+ P ++L V+W
Sbjct 1500 SYKLRVKATNDIGDSDYSAET------EAVTTLQDVPDEPPSSVLVTPHTTSSVLVQWQP 1553
Query 446 PR-ESVKKYILEW------------------------CVLSDKAPCITDWQQEDGTVHRT 480
P+ ES+ +L + + ++ P + + T
Sbjct 1554 PKAESLNGLLLGYRIYYRELDYDAGSATESKAVKNPSALRAELTPQSSFKTVNSSSALTT 1613
Query 481 YLRGNLAESKCY--LITVTPVYADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVL 537
Y L + K Y L+T V + P S ++ ++ +A P+ P ++ + ++ L
Sbjct 1614 YELTQLKKYKRYEVLMTAYNVIGESPTS-TPVEVFVGEAAPAMAPQNIQVNSLSASQLEL 1672
Query 538 EWDQLPVDVQNGFIRNYTIFY-RTIIGNET-AVNVDSSHTEYTLS-SLTSDTLYMVRMAA 594
WD P D QNG I+ Y I+Y + N+T V V SS + + S +LTS T Y+V ++A
Sbjct 1673 TWDPPPADSQNGNIQGYKIYYWEGDVQNDTEKVKVFSSLRQLSASKNLTSHTRYLVCISA 1732
Query 595 YTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAF 629
+ G DGP + P + A P L F
Sbjct 1733 FNAAG--DGPR---SRPSAGRTHQAAPSAPSFLVF 1762
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 93/404 (23%), Positives = 165/404 (41%), Gaps = 45/404 (11%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW----SQIPPEDT 277
P+ P NL + S + L+W P + +L Y ++ +++ S W S + P+ T
Sbjct 620 PHSPQNLLATLNSSYSRSVVLSWVRPFDGNSPVLYYMVEL-SENNSPWKVHLSNLDPKMT 678
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
S TV L P Y FR+ + + GKG +S E S + + P AP K
Sbjct 679 -----SVTVSGLTPARTYQFRVCAVNQVGKG---QYSSETSRLMLPEEPPSAPP---KNI 727
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDY--EVTLTRWKSHLQNYTVNATKLTVNLTNDR 395
+ + +++ + W+ P E NG + Y L Q + + ++ L D
Sbjct 728 VASGRTNQSIMVQWQPPPESEHNGVLHGYILRYRLAGLPGEYQYKNITSAEINYCLVTDL 787
Query 396 YLAT---LTVRNLVGKSDAAVLTIPACDFQ----ATHPVMDLKAFPKDN-MLWVEWTTPR 447
+ T + V + G A + P ++ T P +++ ++ + W+ P
Sbjct 788 IIWTQYEIQVASYNGAGLGA-FSRPVTEYTLQGVPTAPPQNVQVEAVNSTTIQFLWSPPP 846
Query 448 ESVKKYI------LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV----T 497
+ I L W V + + + + VH + NL + Y +V T
Sbjct 847 QQFINGINQGYKLLAWPVDAPGSVTVVTIAPDFHGVHSGCIT-NLKKYTTYYTSVLCFTT 905
Query 498 PVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
P DGP S + L+ P + G T+ + + V W Q PV+ +NG I Y +
Sbjct 906 P--GDGPRSAPQLLRTLEDKPGAVGHLSFTEILDTSLKV-SW-QEPVE-KNGIITGYQLS 960
Query 558 YRTIIGNET--AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ NE+ + ++ EY ++ L+S T Y + +AA T +G
Sbjct 961 WEVYGRNESRLTRTLTNTTLEYKITGLSSLTTYTIEVAAVTAKG 1004
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 85/344 (25%), Positives = 135/344 (39%), Gaps = 44/344 (13%)
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI-TYEDRPSKAPSFWYKIDPSHTQG 343
T+QDL+ +TEY +I+ G G W+ E G+ T E PS P S TQ
Sbjct 1190 TIQDLEEWTEYELQIQAFNAIGAGPWN----EVVGVRTRESVPSAPPENVSAEAVSSTQ- 1244
Query 344 YRTVQLVWKTLPPFEANGKILDYEV------------TLTRWKSHLQNYTVNATKLTVNL 391
+ L W +P E NG IL Y++ + T +H Q+ ++ + V L
Sbjct 1245 ---ILLTWSAVPESEQNGLILGYKILYKAKDLDSEPRSQTVRGNHTQSCLLSGLRKYV-L 1300
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE--WTTPRES 449
R LA + + G + VLT D A P + L FP+ + V W P E
Sbjct 1301 YEIRVLAFTRIGD--GVPSSPVLTERTKD-DAPGPPIRL-VFPEVRLTSVRIVWQPPEEP 1356
Query 450 ---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ Y + + + S T E G+ R + +L Y+ + G G
Sbjct 1357 NGIILGYQIAYRLASSSPNKFTT--VEVGSTVRQFTATDLTPESAYIFRTSAKTRQGWGE 1414
Query 507 PE-----SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI 561
P + + + APP + T ++ V L W +P + IR +T+ R +
Sbjct 1415 PLEATVITTEKRERPAPPQQLTTPQS-DVSSRSLQLHW--VPGSDGSSPIRYFTVQVREL 1471
Query 562 IGNE---TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ + ++ T + SL T Y +R+ A D G D
Sbjct 1472 PNGDWQTYSSSISHEATSCIIESLNPFTSYKLRVKATNDIGDSD 1515
Score = 41.6 bits (96), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 6/123 (5%)
Query 508 ESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT--IIGN 564
E + +++ PS P V + V + +L W +P QNG I Y I Y+ +
Sbjct 1217 EVVGVRTRESVPSAPPENVSAEAVSSTQILLTWSAVPESEQNGLILGYKILYKAKDLDSE 1276
Query 565 ETAVNVDSSHTEYT-LSSLTSDTLYMVRMAAYT--DEGGKDGPEFTFTTPKFAQGEIEAI 621
+ V +HT+ LS L LY +R+ A+T +G P T T A G +
Sbjct 1277 PRSQTVRGNHTQSCLLSGLRKYVLYEIRVLAFTRIGDGVPSSPVLTERTKDDAPGPPIRL 1336
Query 622 VVP 624
V P
Sbjct 1337 VFP 1339
Score = 40.0 bits (92), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 73/282 (26%), Positives = 116/282 (41%), Gaps = 27/282 (10%)
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTR----WKSHLQNYTVNATKLTVN-LTNDR-YLA 398
R+V L W + PF+ N +L Y V L+ WK HL N T +TV+ LT R Y
Sbjct 636 RSVVLSW--VRPFDGNSPVLYYMVELSENNSPWKVHLSNLDPKMTSVTVSGLTPARTYQF 693
Query 399 TLTVRNLVGK----SDAAVLTIPACDFQATHPVMDLKAFPKDNM-LWVEWTTPRESVKKY 453
+ N VGK S+ + L +P + + P ++ A + N + V+W P ES
Sbjct 694 RVCAVNQVGKGQYSSETSRLMLP--EEPPSAPPKNIVASGRTNQSIMVQWQPPPESEHNG 751
Query 454 ILEWCVLSDK-APCITDWQQEDGTVHRTY--LRGNLAESKCYLITVTPVYADGPGS-PES 509
+L +L + A ++Q ++ T L +L Y I V G G+
Sbjct 752 VLHGYILRYRLAGLPGEYQYKNITSAEINYCLVTDLIIWTQYEIQVASYNGAGLGAFSRP 811
Query 510 IKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI--IGNET 566
+ Y Q P+ P V+ + V W P NG + Y + + G+ T
Sbjct 812 VTEYTLQGVPTAPPQNVQVEAVNSTTIQFLWSPPPQQFINGINQGYKLLAWPVDAPGSVT 871
Query 567 AVNVDSS-HTEYT--LSSLTSDTLYMVRMAAYTDEGGKDGPE 605
V + H ++ +++L T Y + +T G DGP
Sbjct 872 VVTIAPDFHGVHSGCITNLKKYTTYYTSVLCFTTPG--DGPR 911
Score = 40.0 bits (92), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 97/446 (22%), Positives = 161/446 (36%), Gaps = 47/446 (11%)
Query 194 IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS-V 252
IEV G VTS I+ V P P NL + N S+ L+ P
Sbjct 995 IEVAAVTAKGSGWVTSSTISSG-VPPELPGAPSNLVISNISPRSATLQF---RPGYDGKT 1050
Query 253 IILKYNIQYRTK---DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
I K+ ++ + + W + D V +L P+T Y FR+R + G
Sbjct 1051 SICKWIVEGQVGVLGEEEEWVSLHEVDNEPDAQMLEVPNLTPYTHYRFRMRQVNVVGASP 1110
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
S S T + P AP T ++++ W LP + NG
Sbjct 1111 LSQPSRVIQ--TLQAPPDVAPGS----VSVRTASESSLRMRWVPLPDTQYNGNPESVGYR 1164
Query 370 LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG--------KSDAAVLTIPACDF 421
+ W+ LQ + + + +DR T+++L ++ A+ P +
Sbjct 1165 IKFWRVDLQPSAL------LKVISDRLERECTIQDLEEWTEYELQIQAFNAIGAGPWNEV 1218
Query 422 QATHPVMDLKAFPKDNM---------LWVEWTT-PRESVKKYILEWCVLSDKAPCITD-- 469
+ + P +N+ + + W+ P IL + +L ++
Sbjct 1219 VGVRTRESVPSAPPENVSAEAVSSTQILLTWSAVPESEQNGLILGYKILYKAKDLDSEPR 1278
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT-- 527
Q G ++ L L + Y I V G G P S + + GP +R
Sbjct 1279 SQTVRGNHTQSCLLSGLRKYVLYEIRVLAFTRIGDGVPSSPVLTERTKDDAPGPPIRLVF 1338
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYTLSSLTS 584
+V + W P + NG I Y I YR + T V V S+ ++T + LT
Sbjct 1339 PEVRLTSVRIVWQ--PPEEPNGIILGYQIAYRLASSSPNKFTTVEVGSTVRQFTATDLTP 1396
Query 585 DTLYMVRMAAYTDEGGKDGPEFTFTT 610
++ Y+ R +A T +G + E T T
Sbjct 1397 ESAYIFRTSAKTRQGWGEPLEATVIT 1422
Score = 38.5 bits (88), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 101/451 (22%), Positives = 174/451 (39%), Gaps = 69/451 (15%)
Query 195 EVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSI-LKLTWTN--PSIK 250
E+ ++A NA+G ++ + V PP N+S +E +SS + LTW+ S +
Sbjct 1201 ELQIQAFNAIGAGPWNEVVGVRTRESVPSAPPENVS---AEAVSSTQILLTWSAVPESEQ 1257
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
+ +IL Y I Y+ KD + + T+S + L+ + Y R+ G G
Sbjct 1258 NGLILGYKILYKAKDLDSEPRSQTVRGNHTQSCL-LSGLRKYVLYEIRVLAFTRIGDGV- 1315
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
+S + E AP ++ + +V++VW+ PP E NG IL Y++
Sbjct 1316 -----PSSPVLTERTKDDAPGPPIRLVFPEVR-LTSVRIVWQ--PPEEPNGIILGYQIAY 1367
Query 371 TRWKSHLQNYTVNATKLTV------NLTNDR-YLATLTVRNLVGKSD---AAVLTI---- 416
S +T TV +LT + Y+ + + G + A V+T
Sbjct 1368 RLASSSPNKFTTVEVGSTVRQFTATDLTPESAYIFRTSAKTRQGWGEPLEATVITTEKRE 1427
Query 417 -PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
PA Q T P D+ + + WV + ++ + ++ L + DWQ
Sbjct 1428 RPAPPQQLTTPQSDVSSR-SLQLHWVPGSDGSSPIRYFTVQVRELPNG-----DWQTYSS 1481
Query 476 TVHR---TYLRGNLAESKCYLITV--TPVYADGPGSPESIKAYLKQAPPSKGPT-VRTKK 529
++ + + +L Y + V T D S E+ Q P + P+ V
Sbjct 1482 SISHEATSCIIESLNPFTSYKLRVKATNDIGDSDYSAETEAVTTLQDVPDEPPSSVLVTP 1541
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI------------IGNETA---------- 567
+ +++W + NG + Y I+YR + + N +A
Sbjct 1542 HTTSSVLVQWQPPKAESLNGLLLGYRIYYRELDYDAGSATESKAVKNPSALRAELTPQSS 1601
Query 568 ---VNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
VN S+ T Y L+ L Y V M AY
Sbjct 1602 FKTVNSSSALTTYELTQLKKYKRYEVLMTAY 1632
>sp|Q8K4B4|IL23R_MOUSE Interleukin-23 receptor OS=Mus musculus
OX=10090 GN=Il23r PE=2 SV=1
Length=644
Score = 77.8 bits (190), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 88/333 (26%), Positives = 152/333 (46%), Gaps = 48/333 (14%)
Query 2 LTLQTWLVQALFIFLTTESTGELLDPCG---YISPESPVVQLHSNFTAVCVLKEKCMDYF 58
LTLQ +V AL++ G C ++ P + Q+ N + C K
Sbjct 4 LTLQLHVVIALYVLFRWCHGGITSINCSGDMWVEP-GEIFQMGMNVSIYCQEALK----- 57
Query 59 HVNANYIVWKTNHFTIPKEQYTI--INRTASSVTFTDIASLNIQLTCNILTFGQLEQN-V 115
H + + N F KE++ I INRT + + + + + + C G ++ +
Sbjct 58 HCRPRNLYFYKNGF---KEEFDITRINRTTARIWYKGFSEPHAYMHCTAECPGHFQETLI 114
Query 116 YGITIISGLPPEKPKNLSCIVNE-GKKMRCEWDGGRETHLETNF-----TLKSEWATHKF 169
G I SG PP+ P NL+C++ E M C W+ G+ T+++T + +L++E
Sbjct 115 CGKDISSGHPPDAPSNLTCVIYEYSGNMTCTWNTGKPTYIDTKYIVHVKSLETEEEQQYL 174
Query 170 ADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD--HINFDPVYKVKPNPPHN 227
A K T ++ S Y VWV+A N+LG S H++ D + V P+
Sbjct 175 ASSYVKISTD---SLQGSRKYL----VWVQAVNSLGMENSQQLHVHLDDI--VIPSA--- 222
Query 228 LSVINSEELS--SILK--LTWTNPSIKSVIILKYNIQYRTKDASTWS--QIPPEDTASTR 281
S+I+ E + ++ K + W + ++ + + ++Y+T TWS + T +
Sbjct 223 -SIISRAETTNDTVPKTIVYWKSKTMIEKVFCE--MRYKTTTNQTWSVKEFDANFTYVQQ 279
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
S F L+P ++YVF++RC +E GK W WS
Sbjct 280 SEFY---LEPDSKYVFQVRC-QETGKRNWQPWS 308
>sp|P16471|PRLR_HUMAN Prolactin receptor OS=Homo sapiens OX=9606
GN=PRLR PE=1 SV=1
Length=622
Score = 72.8 bits (177), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 57/203 (28%), Positives = 92/203 (45%), Gaps = 21/203 (10%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL----KSEWATHKFADCKAKRDTP 179
LPP KP+ C + C W G + L TN++L + E H+ D P
Sbjct 26 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPD--YITGGP 83
Query 180 TSCTV--DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEE 235
SC Y++++ I + V A N +G SD + D Y V+P+PP L+ V E+
Sbjct 84 NSCHFGKQYTSMWRTYI-MMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPED 142
Query 236 LSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
L + W+ P++ + L Y I+ + + A+ W A ++ F + L P
Sbjct 143 RKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEI----HFAGQQTEFKILSLHP 198
Query 292 FTEYVFRIRCMKEDGKGYWSDWS 314
+Y+ ++RC + GYWS WS
Sbjct 199 GQKYLVQVRCKPD--HGYWSAWS 219
>sp|A7MBJ4|PTPRF_BOVIN Receptor-type tyrosine-protein phosphatase
F OS=Bos taurus OX=9913 GN=PTPRF PE=2 SV=1
Length=1898
Score = 73.6 bits (179), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 115/414 (28%), Positives = 166/414 (40%), Gaps = 61/414 (15%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
K P PP +L V +E ++ + LTW S S + Y IQYR A Q + A
Sbjct 316 KALPKPPIDLVV--TETTATSVTLTWD--SGNSEPVSYYGIQYRPAGAEGPFQ-EVDGVA 370
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+TR +++ L PF+EY FR+ + G+G SE T E PS P +
Sbjct 371 TTR--YSIGGLSPFSEYAFRVLAVNSIGRG---PPSEAVRARTGEQAPSSPP----RRVQ 421
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEV--------TLTRWKSHLQNYTVNAT--KLT 388
+ T+ + W+ PP E NG + Y V L+ W H + + T L
Sbjct 422 ARMLSASTMLVQWE--PPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLL 479
Query 389 VNLTND-RYLATLTVRN------LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
+T R LA V + + K+ V PA DFQA D + +
Sbjct 480 PGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPA-DFQA--------EVDSDTRIQL 530
Query 442 EWTTP-RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT--YLRGNLAESKCYLITVTP 498
W P +E + KY L + D+ QQ T T Y +L Y +
Sbjct 531 SWLLPPQERIVKYELVYWAAEDEG------QQHKVTFDPTSSYTVEDLKPDTLYRFQLAA 584
Query 499 VYADGPG--SPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYT 555
G G +P +I+A Q+ PS P V VG + W P D +NG I Y+
Sbjct 585 RSELGVGVFTP-TIEARTAQSTPSAPPQKVTCVSVGSTTVRVSWVPPPADSRNGVITQYS 643
Query 556 IFYRTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ Y + G + +V H+ + L L T Y V + A+TD G GPE
Sbjct 644 VAYEAVDGEDRGRHVVDGIGREHSSWDLVGLEKWTEYRVWVRAHTDVG--PGPE 695
Score = 68.9 bits (167), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 96/404 (24%), Positives = 171/404 (42%), Gaps = 46/404 (11%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSV--IILKYNIQYRTKDASTWSQIPPEDTASTR 281
PP ++ ++ S+ ++++W P S +I +Y++ Y D + +
Sbjct 609 PPQKVTCVSVG--STTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGIGREH 666
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI---TYEDRPSKAPSFWYKIDP 338
SS+ + L+ +TEY +R + G G E+S + T ED PS P +++P
Sbjct 667 SSWDLVGLEKWTEYRVWVRAHTDVGPG------PESSPVLVRTDEDVPS-GPPRKVEVEP 719
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH-------LQNYTV-NATKLTVN 390
++ V++ WK P + +G+I Y+VT R ++ +Q+ + A + T++
Sbjct 720 LNSTA---VRVSWKLPVPSKQHGQIRGYQVTYVRLENGEPRGAPIIQDVMLAEAQETTIS 776
Query 391 LTNDRYLATLTVRNLVGKSDAA------VLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
++TV K D A V T A + T V N ++W
Sbjct 777 GLTPETTYSITVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMVSTTAM----NTALLQWH 832
Query 445 TPRE---SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
P+E + Y L++ + P D+ ++D + + L + Y+ +T
Sbjct 833 PPKELPGELLGYRLQYRRADEARPSTIDFGKDD----QHFTVTGLHKGATYIFRLTAKNR 888
Query 502 DGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G G + + PS P +R + + L WD + +NG I NYT+ YR
Sbjct 889 AGLGEEFEKEITTPEDVPSGFPQNLRVIGLTTSTTELIWDPPVLAERNGRITNYTVVYRD 948
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
I + NV ++ T TLS L DT Y +++ A T +G GP
Sbjct 949 INSQQELQNV-TADTHLTLSGLKPDTTYDIKVRARTSKGA--GP 989
Score = 35.0 bits (79), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 97/406 (24%), Positives = 153/406 (38%), Gaps = 56/406 (14%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQY---RTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
+S + + W P + ++ Y + Y + S W + + T TV L P
Sbjct 427 ASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLT----TVGSLLPGI 482
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
Y R+ G G S + T + P++ F ++D S T+ +QL W
Sbjct 483 TYSLRVLAFTAVGDGPPSPTIQVK---TQQGVPAQPADFQAEVD-SDTR----IQLSW-L 533
Query 354 LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAV 413
LPP E +I+ YE+ + Q + V + D TL L +S+ V
Sbjct 534 LPPQE---RIVKYELVYWAAEDEGQQHKVTFDPTSSYTVEDLKPDTLYRFQLAARSELGV 590
Query 414 ----LTIPACDFQATHPVMDLKAF---PKDNMLWVEWTTP-RESVKKYILEWCVL----- 460
TI A Q+T K + V W P +S I ++ V
Sbjct 591 GVFTPTIEARTAQSTPSAPPQKVTCVSVGSTTVRVSWVPPPADSRNGVITQYSVAYEAVD 650
Query 461 -SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK---- 515
D+ + D G H ++ L + Y + V GPG PES ++
Sbjct 651 GEDRGRHVVDG---IGREHSSWDLVGLEKWTEYRVWVRAHTDVGPG-PESSPVLVRTDED 706
Query 516 --QAPPSKGPTVRTKKVGKNEAVLEWDQLPV-DVQNGFIRNYTIFYRTIIGNE---TAVN 569
PP K V + + + W +LPV Q+G IR Y + Y + E +
Sbjct 707 VPSGPPRK---VEVEPLNSTAVRVSW-KLPVPSKQHGQIRGYQVTYVRLENGEPRGAPII 762
Query 570 VD---SSHTEYTLSSLTSDTLYMVRMAAYT--DEGGKDGPEFTFTT 610
D + E T+S LT +T Y + +AAYT +G + P+ TT
Sbjct 763 QDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARSKPKIVTTT 808
>sp|A2A8L5|PTPRF_MOUSE Receptor-type tyrosine-protein phosphatase
F OS=Mus musculus OX=10090 GN=Ptprf PE=1 SV=1
Length=1898
Score = 70.9 bits (172), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 112/414 (27%), Positives = 165/414 (40%), Gaps = 61/414 (15%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
K P PP +L V +E ++ + LTW + + + V Y IQYR Q + A
Sbjct 316 KALPKPPIDLVV--TETTATSVTLTWDSGNTEPVSF--YGIQYRAAGTDGPFQ-EVDGVA 370
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
STR +++ L PF+EY FR+ + G+G SE T E PS P +
Sbjct 371 STR--YSIGGLSPFSEYAFRVLAVNSIGRG---PPSEAVRARTGEQAPSSPP----RRVQ 421
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEV--------TLTRWKSHLQNYTVNAT--KLT 388
+ T+ + W+ PP E NG + Y V L+ W H + + T L
Sbjct 422 ARMLSASTMLVQWE--PPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLL 479
Query 389 VNLTND-RYLATLTVRN------LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
+T R LA V + + K+ V PA DFQA D + +
Sbjct 480 PGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPA-DFQANA--------ESDTRIQL 530
Query 442 EWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT--YLRGNLAESKCYLITVTP 498
W P+E + KY L + D+ QQ T T Y +L Y +
Sbjct 531 SWLLPPQERIVKYELVYWAAEDEG------QQHKVTFDPTSSYTLEDLKPDTLYHFQLAA 584
Query 499 VYADGPG--SPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYT 555
G G +P +++A Q+ PS P V G + W P D +NG I Y+
Sbjct 585 RSDLGVGVFTP-TVEARTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYS 643
Query 556 IFYRTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ Y + G + +V H+ + L L T Y V + A+TD G GPE
Sbjct 644 VAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVG--PGPE 695
Score = 69.7 bits (169), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 95/405 (23%), Positives = 168/405 (41%), Gaps = 48/405 (12%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSV--IILKYNIQYRTKDASTWSQIPPEDTASTR 281
PP ++ +++ S+ ++++W P S II +Y++ Y D + + +
Sbjct 609 PPQKVTCVSTG--STTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREH 666
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI---TYEDRPSKAPSFWYKIDP 338
SS+ + L+ +TEY +R + G G E+S + T ED PS P +++P
Sbjct 667 SSWDLLGLEKWTEYRVWVRAHTDVGPG------PESSPVLVRTDEDVPS-GPPRKVEVEP 719
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK---------------SHLQNYTVN 383
++ V + WK P + +G+I Y+VT R + + Q T++
Sbjct 720 LNSTA---VHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTIS 776
Query 384 ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEW 443
LT T +A T + +S V+T P M + L ++W
Sbjct 777 G--LTPETTYSITVAAYTTKGDGARSKPKVVTTTGA--VPGRPTMMVSTTAMHTAL-LQW 831
Query 444 TTPRE---SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY 500
P+E + Y L++ + P D+ ++D + + L + Y+ +
Sbjct 832 HPPKELPGELLGYRLQYRRADEARPNTIDFGKDD----QHFTVTGLHKGATYVFRLAAKN 887
Query 501 ADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
GPG + + PS P +R + + L WD + +NG I NYT+ YR
Sbjct 888 RAGPGEEFEKEITTPEDVPSGFPQNLRVTGLTTSTTELTWDPPVLAERNGHITNYTVVYR 947
Query 560 TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
I NV ++ T TL L DT Y +++ A+T +G GP
Sbjct 948 DINSQLELQNV-TNDTHLTLLGLKPDTTYDIKVRAHTSKGA--GP 989
Score = 34.3 bits (77), Expect = 7.4, Method: Compositional matrix adjust.
Identities = 36/123 (29%), Positives = 55/123 (45%), Gaps = 20/123 (16%)
Query 503 GPGSPESIKAYLK------QAPPSKGPTVRTKKVGKNEAVLEWDQLPV-DVQNGFIRNYT 555
GPG PES ++ PP K V + + + W +LPV + Q+G IR Y
Sbjct 691 GPG-PESSPVLVRTDEDVPSGPPRK---VEVEPLNSTAVHVSW-KLPVPNKQHGQIRGYQ 745
Query 556 IFYRTIIGNETAVN------VDSSHTEYTLSSLTSDTLYMVRMAAYT--DEGGKDGPEFT 607
+ Y + E + + E T+S LT +T Y + +AAYT +G + P+
Sbjct 746 VTYVRLENGEPRGQPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARSKPKVV 805
Query 608 FTT 610
TT
Sbjct 806 TTT 808
>sp|Q64604|PTPRF_RAT Receptor-type tyrosine-protein phosphatase
F OS=Rattus norvegicus OX=10116 GN=Ptprf PE=2 SV=1
Length=1898
Score = 70.5 bits (171), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 114/414 (28%), Positives = 167/414 (40%), Gaps = 61/414 (15%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
K P PP +L V +E ++ + LTW + + + V Y IQYR Q + A
Sbjct 316 KALPKPPIDLVV--TETTATSVTLTWDSGNTEPVSF--YGIQYRAAGTDGPFQ-EVDGVA 370
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
STR +++ L PF+EY FR+ + G+G SE T E PS P +
Sbjct 371 STR--YSIGGLSPFSEYAFRVLAVNSIGRG---PPSEAVRARTGEQAPSSPP----RRVQ 421
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEV--------TLTRWKSHLQNYTVNAT--KLT 388
+ T+ + W+ PP E NG + Y V L+ W H + + T L
Sbjct 422 ARMLSASTMLVQWE--PPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLL 479
Query 389 VNLTND-RYLATLTVRN------LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
+T R LA V + + K+ V PA DFQA KA D + +
Sbjct 480 PGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPA-DFQA-------KA-ESDTRIQL 530
Query 442 EWTTP-RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT--YLRGNLAESKCYLITVTP 498
W P +E + KY L + D+ QQ T T Y +L Y +
Sbjct 531 SWLLPPQERIIKYELVYWAAEDEG------QQHKVTFDPTSSYTLEDLKPDTLYHFQLAA 584
Query 499 VYADGPG--SPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYT 555
G G +P +++A Q+ PS P V G + W P D +NG I Y+
Sbjct 585 RSDLGVGVFTP-TVEACTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYS 643
Query 556 IFYRTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ Y + G + +V H+ + L L T Y V + A+TD G GPE
Sbjct 644 VAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVG--PGPE 695
Score = 69.3 bits (168), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 94/405 (23%), Positives = 166/405 (41%), Gaps = 48/405 (12%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSV--IILKYNIQYRTKDASTWSQIPPEDTASTR 281
PP ++ +++ S+ ++++W P S II +Y++ Y D + + +
Sbjct 609 PPQKVTCVSTG--STTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREH 666
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI---TYEDRPSKAPSFWYKIDP 338
SS+ + L+ +TEY +R + G G E+S + T ED PS P +++P
Sbjct 667 SSWDLLGLEKWTEYRVWVRAHTDVGPG------PESSPVLVRTDEDVPS-GPPRKVEVEP 719
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK---------------SHLQNYTVN 383
++ V + WK P + +G+I Y+VT R + + Q T++
Sbjct 720 LNSTA---VHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTIS 776
Query 384 ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEW 443
LT T +A T + +S V+T P M + L ++W
Sbjct 777 G--LTPETTYSITVAAYTTKGDGARSKPKVVTTTGA--VPGRPTMMVSTTAMHTAL-LQW 831
Query 444 TTPRE---SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY 500
P+E + Y L++ + P D+ ++D + + L + Y+ +
Sbjct 832 HPPKELPGELLGYRLQYRRADEARPNTIDFGKDD----QHFTVTGLHKGATYIFRLAAKN 887
Query 501 ADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
GPG + + PS P +R + + L WD + +NG I NYT+ YR
Sbjct 888 RAGPGEEFEKEITTPEDAPSGFPQNLRVTGLTTSTTELAWDPPVLAERNGRITNYTVVYR 947
Query 560 TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
I NV + TL L DT Y +++ A+T +G GP
Sbjct 948 DINSQHELQNV-TGDVHLTLLGLKPDTTYDIKVRAHTSKGA--GP 989
>sp|Q08406|CNTFR_RAT Ciliary neurotrophic factor receptor subunit
alpha OS=Rattus norvegicus OX=10116 GN=Cntfr PE=2 SV=2
Length=372
Score = 67.4 bits (163), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 57/209 (27%), Positives = 88/209 (42%), Gaps = 13/209 (6%)
Query 123 GLPPEKPKNLSCIVNE-GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
GLPP +P LSC N K C W T++ F + + K C+
Sbjct 106 GLPPREPV-LSCRSNTYPKGFYCSWHLSAPTYIPNTFNVTVLHGS-KMMVCEKDPALKNR 163
Query 182 CTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
C + Y ++ + +V + NALG T+ I FD VKP+PP N+ L
Sbjct 164 CHIRYMHLFSTIKYKVSISVSNALGHNTTA-ITFDEFTIVKPDPPENVVARPVPSNPRRL 222
Query 241 KLTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
++TW PS LK+ ++YR W + S ++ T+ D EY+
Sbjct 223 EVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHV----ELSNGTAHTITDAYAGKEYII 278
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRP 326
++ K++ G WSDWS A + + P
Sbjct 279 QV-AAKDNEIGTWSDWSVAAHATPWTEEP 306
>sp|P23468|PTPRD_HUMAN Receptor-type tyrosine-protein phosphatase
delta OS=Homo sapiens OX=9606 GN=PTPRD PE=1 SV=2
Length=1912
Score = 68.9 bits (167), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 113/410 (28%), Positives = 180/410 (44%), Gaps = 54/410 (13%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS-TWSQIPPEDT 277
K P PP V +E ++ + LTW + + + V Y IQ++ K++ + +I +
Sbjct 320 KALPKPPGTPVV--TESTATSITLTWDSGNPEPVSY--YIIQHKPKNSEELYKEI--DGV 373
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
A+TR ++V L P+++Y FR+ + G+G SE T E PS AP
Sbjct 374 ATTR--YSVAGLSPYSDYEFRVVAVNNIGRG---PPSEPVLTQTSEQAPSSAPRDVQARM 428
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQN---YTVNATKLTV--NL 391
S T T+ + WK P E NG+I Y V T + H+ N + V +++T NL
Sbjct 429 LSST----TILVQWKE--PEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNL 482
Query 392 TNDR-----YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK-DNMLWVEWTT 445
+ LA ++ + SD V+T Q ++ KA P+ + + + WT
Sbjct 483 VPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP----LNFKAEPESETSILLSWTP 538
Query 446 PR-ESVKKYILEWCVLSDKAPCITDWQQ---EDGTVHRTYLRGNLAESKCYLITVTPVYA 501
PR +++ Y L + K + Q+ E GT +R L+G L + Y +
Sbjct 539 PRSDTIANYELVY-----KDGEHGEEQRITIEPGTSYR--LQG-LKPNSLYYFRLAARSP 590
Query 502 DGPG-SPESIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
G G S I A Q+ PS P + ++ W PV+ QNG I Y+I Y
Sbjct 591 QGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYT 650
Query 560 TIIGNETA----VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ G + + + S T+Y L L T Y + + A+TD G GPE
Sbjct 651 AVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVG--PGPE 698
Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 92/406 (23%), Positives = 152/406 (37%), Gaps = 47/406 (12%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P P N E +SIL L+WT P +S I Y + Y+ + +I T
Sbjct 516 PGQPLNFKA-EPESETSIL-LSWTPP--RSDTIANYELVYKDGEHGEEQRI----TIEPG 567
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+S+ +Q LKP + Y FR+ G G + E S T + +PS P PS T
Sbjct 568 TSYRLQGLKPNSLYYFRLAARSPQGLG---ASTAEISARTMQSKPSAPPQDISCTSPSST 624
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRW-----KSH-LQNYTVNATKLTVNLTND- 394
++ + W+ P + NG I +Y + T K H + + TK +
Sbjct 625 ----SILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKW 680
Query 395 -RYLATLTVRNLVGKS--DAAVLTIPACDFQATHPV-MDLKAFPKDNMLWVEWTTP---- 446
Y T+T VG +VL D + P ++++A + V W +P
Sbjct 681 TEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAV-NSTSVKVSWRSPVPNK 739
Query 447 -RESVKKYILEWCVLSDKAP-----------CITDWQQEDGTVHRTYLRGNLAESKCYLI 494
++ Y + + + + P W+ +D T H + G L Y +
Sbjct 740 QHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISG-LQPETSYSL 798
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
TVT G G+ K P + N A+++W PVD G ++ Y
Sbjct 799 TVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQW-HPPVDT-FGPLQGY 856
Query 555 TI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ F R + T + +T + + Y+ R++A G
Sbjct 857 RLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVG 902
Score = 35.0 bits (79), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 39/153 (25%), Positives = 59/153 (39%), Gaps = 27/153 (18%)
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK------QAPPSKGPTVRTKKVGKNE 534
YL L + Y ITVT GPG PES+ ++ PP K V + V
Sbjct 672 YLLEQLEKWTEYRITVTAHTDVGPG-PESLSVLIRTNEDVPSGPPRK---VEVEAVNSTS 727
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV---------------DSSHTEYTL 579
+ W + Q+G IR Y + Y + E D++ + +
Sbjct 728 VKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMII 787
Query 580 SSLTSDTLYMVRMAAYT--DEGGKDGPEFTFTT 610
S L +T Y + + AYT +G + P+ TT
Sbjct 788 SGLQPETSYSLTVTAYTTKGDGARSKPKLVSTT 820
Score = 34.7 bits (78), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 26/79 (33%), Positives = 38/79 (48%), Gaps = 7/79 (9%)
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS----SHTEYTLSSLTSDTLYMVRM 592
L W + +NG I YT+ YR I N + ++ + T TL+ L DT Y V++
Sbjct 937 LSWQPPVLAERNGIITKYTLLYRDI--NIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKV 994
Query 593 AAYTDEG-GKDGPEFTFTT 610
A+T +G G P F T
Sbjct 995 RAHTSKGPGPYSPSVQFRT 1013
>sp|Q7Z5N4|SDK1_HUMAN Protein sidekick-1 OS=Homo sapiens OX=9606
GN=SDK1 PE=2 SV=3
Length=2213
Score = 68.9 bits (167), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 117/486 (24%), Positives = 191/486 (39%), Gaps = 68/486 (14%)
Query 191 FVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
FV E+ V A +G V S + + P PP L V L+S+ ++ W P
Sbjct 1346 FVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRL-VFPEVRLTSV-RIVWQPPEE 1403
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ IIL Y I YR +S + E A+ R FT DL P + Y+FR+ G
Sbjct 1404 PNGIILGYQIAYRLASSSPHTFTTVEVGATVRQ-FTATDLAPESAYIFRLSAKTRQG--- 1459
Query 310 WSDWSE--EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY- 366
W E EA+ IT E R AP + P R+++L W +P + I +
Sbjct 1460 ---WGEPLEATVITTEKRERPAPPRELLV-PQAEVTARSLRLQW--VPGSDGASPIRYFT 1513
Query 367 ----EVTLTRWKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPACD 420
E+ W+++ + + AT V+ Y L N +G SD + T
Sbjct 1514 MQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTT 1573
Query 421 FQ--ATHPVMDLKAFPKD-NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
Q P + A P + + ++W PR+ +L+ + + +++ GT
Sbjct 1574 LQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRE---LEYEAGSGTE 1630
Query 478 HRTY-----LRGNLAESKCY-------------------------LITVTPVYADGPGSP 507
+T L L + ++T + + P S
Sbjct 1631 AKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPAS- 1689
Query 508 ESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNE 565
++ ++ +A P+ P V+ + ++ + WD P + QNG I+ Y I+Y NE
Sbjct 1690 APVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNE 1749
Query 566 TAVNVDSSHTE--YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
T E L +LTS T Y+V ++A+ G DGP+ + P+ + A
Sbjct 1750 TEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAG--DGPK---SDPQQGRTHQAAPGA 1804
Query 624 PVCLAF 629
P LAF
Sbjct 1805 PSFLAF 1810
Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 86/402 (21%), Positives = 156/402 (39%), Gaps = 41/402 (10%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW----SQIPPEDT 277
P+ P NL V + S + L+W P + IL Y ++ +++ S W S + PE T
Sbjct 668 PHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVEL-SENNSPWKVHLSNVGPEMT 726
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
TV L P Y FR+ + E G+G +S E S + + P AP K
Sbjct 727 G-----VTVSGLTPARTYQFRVCAVNEVGRG---QYSAETSRLMLPEEPPSAPP---KNI 775
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDY--EVTLTRWKSHLQNYTVNATKLTVNLTNDR 395
+ + +++ + W+ P E NG + Y L Q + + ++ L D
Sbjct 776 VASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDL 835
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM---------LWVEWTTP 446
+ T + + A + + T + + P N+ + W P
Sbjct 836 IIWTQYEIQVAAYNGAGLGVFSRAVTEYT--LQGVPTAPPQNVQTEAVNSTTIQFLWNPP 893
Query 447 RESVKKYI------LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY 500
+ I L W + +A + + VH ++ NL + Y +V
Sbjct 894 PQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHIT-NLKKFTAYFTSVLCFT 952
Query 501 ADGPGSPESIK-AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
G G P + + + ++ P + ++ + W Q P++ +NG I Y I +
Sbjct 953 TPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSW-QEPLE-KNGIITGYQISWE 1010
Query 560 TIIGNETAV--NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
N++ + ++S+ EY + L+S T Y + +AA T G
Sbjct 1011 VYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVG 1052
Score = 44.3 bits (103), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 122/530 (23%), Positives = 198/530 (37%), Gaps = 91/530 (17%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA--KRDTPTSC 182
P PKN+ + + +W ET E N L+ ++ A ++ TS
Sbjct 768 PSAPPKNIVASGRTNQSIMVQWQPPPET--EHNGVLRGYILRYRLAGLPGEYQQRNITSP 825
Query 183 TVDYSTV----YFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEEL- 236
V+Y V + E+ V A N G V S + + V PP N + +E +
Sbjct 826 EVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQN---VQTEAVN 882
Query 237 SSILKLTWTNPSIKSVIILKYNIQYR-------TKDASTWSQIPPEDTASTRSSFTVQDL 289
S+ ++ W P + I N Y+ +A T I P+ T +L
Sbjct 883 STTIQFLWNPPPQQ--FINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHIT--NL 938
Query 290 KPFTEYVFRIRCMKEDGKGYWSD----WSEEASGITYEDRPSKAP--SFWYKIDPSHTQG 343
K FT Y + C G G S W T ED+P SF +D S
Sbjct 939 KKFTAYFTSVLCFTTPGDGPPSTPQLVW-------TQEDKPGAVGHLSFTEILDTS---- 987
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN-----YTVNATKLTVNLTNDRYLA 398
+++ W+ P E NG I Y+++ W+ + +N +T+N+T + L
Sbjct 988 ---LKVSWQE--PLEKNGIITGYQIS---WEVYGRNDSRLTHTLNSTTHEYKIQGLSSLT 1039
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVM-----DLKAFPKDNMLWVEWTTPRE----- 448
T T+ D A +T + + DL P + L + +PR
Sbjct 1040 TYTI-------DVAAVTAVGTGLVTSSTISSGVPPDLPGAPSN--LVISNISPRSATLQF 1090
Query 449 --------SVKKYILEWCV--LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
S+ ++I+E V + D+ +T +++E+ + NL Y +
Sbjct 1091 RPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQ 1150
Query 499 VYADGPG--SPESIKAYLKQAPPSKGPTVRTKKVGKNEAV-LEWDQLPVDVQNGFIRN-- 553
V GP SP S QAPP PT T + ++ L W LP NG +
Sbjct 1151 VNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVG 1210
Query 554 YTI-FYRTIIGNETAVNV--DSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
Y I ++R+ + + V D E+T+ L Y ++M A+ G
Sbjct 1211 YRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGA 1260
Score = 37.4 bits (85), Expect = 0.80, Method: Compositional matrix adjust.
Identities = 29/101 (29%), Positives = 48/101 (48%), Gaps = 5/101 (5%)
Query 503 GPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT- 560
GP S E ++ +++ PS P V + V + +L W +P QNG I Y I +R
Sbjct 1261 GPWS-EVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAK 1319
Query 561 -IIGNETAVNVDSSHTEYT-LSSLTSDTLYMVRMAAYTDEG 599
+ + V +HT+ L+ L LY +++ A+T G
Sbjct 1320 DLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIG 1360
Score = 35.4 bits (80), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 82/340 (24%), Positives = 130/340 (38%), Gaps = 34/340 (10%)
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
FT+++L+ + EY +++ G G WSE G T E PS AP S TQ
Sbjct 1237 FTIEELEEWMEYELQMQAFNAVGAG---PWSEVVRGRTRESVPSAAPENVSAEAVSSTQ- 1292
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWK-------SHL--QNYTVNATKLTVNLTND 394
+ L W ++P + NG IL Y++ L R K SH+ N+T +A +
Sbjct 1293 ---ILLTWTSVPEQDQNGLILGYKI-LFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVL 1348
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE--WTTPRES--- 449
L L + + L + A P + L FP+ + V W P E
Sbjct 1349 YELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRL-VFPEVRLTSVRIVWQPPEEPNGI 1407
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-- 507
+ Y + + + S T E G R + +LA Y+ ++ G G P
Sbjct 1408 ILGYQIAYRLASSSPHTFTT--VEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLE 1465
Query 508 -ESIKAYLKQAP-PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE 565
I ++ P P + V +V L+W +P IR +T+ R + E
Sbjct 1466 ATVITTEKRERPAPPRELLVPQAEVTARSLRLQW--VPGSDGASPIRYFTMQVRELPRGE 1523
Query 566 ---TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ ++ T + L T Y +R+ A D G D
Sbjct 1524 WQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSD 1563
>sp|Q64487|PTPRD_MOUSE Receptor-type tyrosine-protein phosphatase
delta OS=Mus musculus OX=10090 GN=Ptprd PE=1 SV=3
Length=1912
Score = 68.6 bits (166), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 112/415 (27%), Positives = 179/415 (43%), Gaps = 64/415 (15%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST-WSQIPPEDT 277
K P PP V +E ++ + LTW + + + V Y IQ++ K++ + +I +
Sbjct 320 KALPKPPGTPVV--TESTATSITLTWDSGNPEPVSY--YIIQHKPKNSEEPYKEI--DGI 373
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
A+TR ++V L P+++Y FR+ + G+G SE T E PS AP
Sbjct 374 ATTR--YSVAGLSPYSDYEFRVVAVNNIGRG---PASEPVLTQTSEQAPSSAPRDVQARM 428
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQN---YTVNATKLTV--NL 391
S T T+ + WK P E NG+I Y V T + H+ N + V +++T NL
Sbjct 429 LSST----TILVQWKE--PEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNL 482
Query 392 TNDR-----YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK-DNMLWVEWTT 445
+ LA ++ + SD V+T Q ++ KA P+ + + + WT
Sbjct 483 VPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP----LNFKAEPESETSILLSWTP 538
Query 446 PR-ESVKKYILEWCVLSDKAPCITDWQQ--------EDGTVHRTYLRGNLAESKCYLITV 496
PR +++ Y L + D Q E GT +R L+G L + Y +
Sbjct 539 PRSDTIASYELVY----------RDGDQGEEQRITIEPGTSYR--LQG-LKPNSLYYFRL 585
Query 497 TPVYADGPG-SPESIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
+ G G S I A Q+ PS P + ++ W PV+ QNG I Y
Sbjct 586 SARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEY 645
Query 555 TIFYRTIIGNE----TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
++ Y + G + + + S T+Y L L T Y + + A+TD G GPE
Sbjct 646 SLKYAAVDGEDFKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVG--PGPE 698
Score = 50.4 bits (119), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 93/406 (23%), Positives = 152/406 (37%), Gaps = 47/406 (12%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P P N E +SIL L+WT P +S I Y + YR D +I T
Sbjct 516 PGQPLNFKA-EPESETSIL-LSWTPP--RSDTIASYELVYRDGDQGEEQRI----TIEPG 567
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+S+ +Q LKP + Y FR+ G G + E S T + +PS P PS T
Sbjct 568 TSYRLQGLKPNSLYYFRLSARSPQGLG---ASTAEISARTMQSKPSAPPQDISCTSPSST 624
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTR-----WKSH-LQNYTVNATKLTVNLTND- 394
++ + W+ P + NG I +Y + +K H + + TK +
Sbjct 625 ----SILVSWQPPPVEKQNGIITEYSLKYAAVDGEDFKPHEILGIPSDTTKYLLEQLEKW 680
Query 395 -RYLATLTVRNLVGKS--DAAVLTIPACDFQATHPV-MDLKAFPKDNMLWVEWTTP---- 446
Y T+T VG +VL D + P ++++A + V W +P
Sbjct 681 TEYRITVTAHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAV-NATAVKVSWRSPVPNK 739
Query 447 -RESVKKYILEWCVLSDKAP-----------CITDWQQEDGTVHRTYLRGNLAESKCYLI 494
++ Y + + + + P W+ +D T H + G L Y +
Sbjct 740 QHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISG-LQPETSYSL 798
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
TVT G G+ K P + N A+++W PVD G ++ Y
Sbjct 799 TVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQW-HPPVDT-FGPLQGY 856
Query 555 TI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ F R + T + +T + + Y+ R++A G
Sbjct 857 RLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVG 902
Score = 36.6 bits (83), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 7/79 (9%)
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS----SHTEYTLSSLTSDTLYMVRM 592
L W + +NG I YT+ YR I N + ++ + T TL+ L SDT Y V++
Sbjct 937 LSWQPPVLAERNGVITKYTLLYRDI--NVPLLPMEHLIVPADTSMTLTGLKSDTTYDVKV 994
Query 593 AAYTDEG-GKDGPEFTFTT 610
A+T +G G P F T
Sbjct 995 RAHTSKGPGPYSPSVQFRT 1013
Score = 35.0 bits (79), Expect = 5.0, Method: Compositional matrix adjust.
Identities = 39/153 (25%), Positives = 59/153 (39%), Gaps = 27/153 (18%)
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK------QAPPSKGPTVRTKKVGKNE 534
YL L + Y ITVT GPG PES+ ++ PP K V + V
Sbjct 672 YLLEQLEKWTEYRITVTAHTDVGPG-PESLSVLIRTDEDVPSGPPRK---VEVEAVNATA 727
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV---------------DSSHTEYTL 579
+ W + Q+G IR Y + Y + E D++ + +
Sbjct 728 VKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMII 787
Query 580 SSLTSDTLYMVRMAAYT--DEGGKDGPEFTFTT 610
S L +T Y + + AYT +G + P+ TT
Sbjct 788 SGLQPETSYSLTVTAYTTKGDGARSKPKLVSTT 820
>sp|Q91513|PRLR_ORENI Prolactin receptor OS=Oreochromis niloticus
OX=8128 GN=prlr PE=2 SV=1
Length=630
Score = 67.8 bits (164), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 55/200 (28%), Positives = 89/200 (45%), Gaps = 19/200 (10%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL----KSEWATHKFADCKAKRDTPTS 181
P KP + C E + C W G + L T + L + H+ D S
Sbjct 29 PGKPTEIKCRSPEKETFTCWWKPGSDGGLPTTYALYYRKEGSDVVHECPDYHTAGKN--S 86
Query 182 CTVDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV-INSEELSSI 239
C + + T+ +V+ + V A NALGK SD + D VY V+P+PP L V + ++
Sbjct 87 CFFNKNNTLIWVSYNITVVATNALGKTYSDPQDIDVVYIVQPHPPEKLEVTVMKDQGWPF 146
Query 240 LKLTWTNPSIKSV----IILKYNIQYRTKD-ASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
L+++W P I L Y ++ + +D S W A + F + L+
Sbjct 147 LRVSWEPPRKADTRSGWITLIYELRVKLEDEESEWEN----HAAGQQKMFNIFSLRSGGT 202
Query 295 YVFRIRCMKEDGKGYWSDWS 314
Y+ ++RC + G+WS+WS
Sbjct 203 YLIQVRCKPD--HGFWSEWS 220
>sp|P10586|PTPRF_HUMAN Receptor-type tyrosine-protein phosphatase
F OS=Homo sapiens OX=9606 GN=PTPRF PE=1 SV=2
Length=1907
Score = 68.2 bits (165), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 112/414 (27%), Positives = 163/414 (39%), Gaps = 61/414 (15%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
K P PP +L V +E ++ + LTW S S + Y IQYR A T D
Sbjct 316 KALPKPPIDLVV--TETTATSVTLTWD--SGNSEPVTYYGIQYRA--AGTEGPFQEVDGV 369
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+T + +++ L PF+EY FR+ + G+G SE T E PS P +
Sbjct 370 AT-TRYSIGGLSPFSEYAFRVLAVNSIGRG---PPSEAVRARTGEQAPSSPP----RRVQ 421
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--------RWKSHLQNYTVNAT--KLT 388
+ T+ + W+ PP E NG + Y V T W H + + T L
Sbjct 422 ARMLSASTMLVQWE--PPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLL 479
Query 389 VNLTND-RYLATLTVRN------LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
+T R LA V + + K+ V PA DFQA D + +
Sbjct 480 PGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPA-DFQA--------EVESDTRIQL 530
Query 442 EWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT--YLRGNLAESKCYLITVTP 498
W P+E + Y L + D+ QQ T T Y +L Y +
Sbjct 531 SWLLPPQERIIMYELVYWAAEDED------QQHKVTFDPTSSYTLEDLKPDTLYRFQLAA 584
Query 499 VYADGPG--SPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYT 555
G G +P +I+A Q+ PS P V +G + W P D +NG I Y+
Sbjct 585 RSDMGVGVFTP-TIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYS 643
Query 556 IFYRTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ Y + G + +V H+ + L L T Y V + A+TD G GPE
Sbjct 644 VAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVG--PGPE 695
Score = 67.8 bits (164), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 90/414 (22%), Positives = 169/414 (41%), Gaps = 65/414 (16%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSV--IILKYNIQYRTKDASTWSQIPPEDTASTR 281
PP + ++ S+ ++++W P S +I +Y++ Y D + + +
Sbjct 609 PPQKVMCVSMG--STTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREH 666
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI---TYEDRPSKAPSFWYKIDP 338
SS+ + L+ +TEY +R + G G E+S + T ED PS P +++P
Sbjct 667 SSWDLVGLEKWTEYRVWVRAHTDVGPG------PESSPVLVRTDEDVPSGPPRK-VEVEP 719
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR---------------------WK-SH 376
++ V + WK P + +G+I Y+VT R W+
Sbjct 720 LNSTA---VHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEE 776
Query 377 LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
++Y + LT T +A T + +S ++T P M + +
Sbjct 777 SEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGA--VPGRPTMMISTTAMN 834
Query 437 NMLWVEWTTPRE---SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
L ++W P+E + Y L++C + P D+ ++D + + L + Y+
Sbjct 835 TAL-LQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDD----QHFTVTGLHKGTTYI 889
Query 494 ITVTPVYADGPG--------SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
+ G G +PE + + Q G T T + L WD +
Sbjct 890 FRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTE-------LAWDPPVLA 942
Query 546 VQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+NG I +YT+ +R I + N+ ++ T +TL+ L DT Y +++ A+T +G
Sbjct 943 ERNGRIISYTVVFRDINSQQELQNI-TTDTRFTLTGLKPDTTYDIKVRAWTSKG 995
Score = 39.7 bits (91), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 84/400 (21%), Positives = 147/400 (37%), Gaps = 42/400 (11%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
++L+W P + +I+ + + + +D ++ T SS+T++DLKP T Y F++
Sbjct 528 IQLSWLLPPQERIIMYEL-VYWAAEDEDQQHKV----TFDPTSSYTLEDLKPDTLYRFQL 582
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
+ G G ++ E T + PS P + + G TV++ W P
Sbjct 583 AARSDMGVGVFTPTIEAR---TAQSTPSAPPQKVMCV----SMGSTTVRVSWVPPPADSR 635
Query 360 NGKILDYEVTLTRWKSHLQNYTV-------NATKLTVNLTN-DRYLATLTVRNLVGKSDA 411
NG I Y V + V +++ V L Y + VG
Sbjct 636 NGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPE 695
Query 412 AVLTIPACDFQA-THPVMDLKAFPKDN-MLWVEWTTPRES-----VKKYILEWCVLSDKA 464
+ + D + P ++ P ++ + V W P S ++ Y + + L +
Sbjct 696 SSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGE 755
Query 465 P----CITD-------WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
P I D W+ E+ + T + G L Y +TV G G+ K
Sbjct 756 PRGLPIIQDVMLAEAQWRPEESEDYETTISG-LTPETTYSVTVAAYTTKGDGARSKPKIV 814
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDS 572
PT+ N A+L+W P G + Y + Y R ++
Sbjct 815 TTTGAVPGRPTMMISTTAMNTALLQWH--PPKELPGELLGYRLQYCRADEARPNTIDFGK 872
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
+T++ L T Y+ R+AA G + E TP+
Sbjct 873 DDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPE 912
>sp|O88507|CNTFR_MOUSE Ciliary neurotrophic factor receptor subunit
alpha OS=Mus musculus OX=10090 GN=Cntfr PE=1 SV=2
Length=372
Score = 66.2 bits (160), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 57/209 (27%), Positives = 88/209 (42%), Gaps = 13/209 (6%)
Query 123 GLPPEKPKNLSCIVNE-GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
GLPP +P LSC N K C W T++ F + + K C+
Sbjct 106 GLPPREPV-LSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGS-KIMVCEKDPALKNR 163
Query 182 CTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
C + Y ++ + +V + NALG T+ I FD VKP+PP N+ L
Sbjct 164 CHIRYMHLFSTIKYKVSISVSNALGHNTTA-ITFDEFTIVKPDPPENVVARPVPSNPRRL 222
Query 241 KLTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
++TW PS LK+ ++YR W + S ++ T+ D EY+
Sbjct 223 EVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHV----ELSDGTAHTITDAYAGKEYII 278
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRP 326
++ K++ G WSDWS A + + P
Sbjct 279 QV-AAKDNEIGTWSDWSVAAHATPWTEEP 306
>sp|P26992|CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit
alpha OS=Homo sapiens OX=9606 GN=CNTFR PE=1 SV=2
Length=372
Score = 65.5 bits (158), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 56/209 (27%), Positives = 87/209 (42%), Gaps = 13/209 (6%)
Query 123 GLPPEKPKNLSCIVNE-GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
GLPP +P LSC N K C W T++ F + + K C+
Sbjct 106 GLPPREPV-LSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGS-KIMVCEKDPALKNR 163
Query 182 CTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
C + Y ++ + +V + NALG + I FD VKP+PP N+ L
Sbjct 164 CHIRYMHLFSTIKYKVSISVSNALGH-NATAITFDEFTIVKPDPPENVVARPVPSNPRRL 222
Query 241 KLTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
++TW PS LK+ ++YR W + S ++ T+ D EY+
Sbjct 223 EVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHV----ELSDGTAHTITDAYAGKEYII 278
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRP 326
++ K++ G WSDWS A + + P
Sbjct 279 QV-AAKDNEIGTWSDWSVAAHATPWTEEP 306
>sp|Q6V4S5|SDK2_MOUSE Protein sidekick-2 OS=Mus musculus OX=10090
GN=Sdk2 PE=1 SV=1
Length=2176
Score = 66.6 bits (161), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 140/626 (22%), Positives = 232/626 (37%), Gaps = 100/626 (16%)
Query 79 YTIINRTASSVTFTDI---ASLNIQLTC-NILTFGQLEQNVYGITIISGLPPEKPKNLSC 134
+T+ +R T D+ +Q+ N + G Q V G T S +P P N+S
Sbjct 1154 HTVQDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSQAVVGRTRES-VPSSGPTNVSA 1212
Query 135 IVNEGKKMRCEWD-------GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
+ M W G + + K + +F + T
Sbjct 1213 LATTSSSMLVRWSEIPEADRNGLVLGYKVRYKEKDSDSQPRFWLVEGNSSRSAQLT---G 1269
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK----PNPPHNLSVINSEELSSILKLT 243
+V EV V A +G + H P+ + P PP + ++ E ++ ++L
Sbjct 1270 LGKYVLYEVQVLAFTRIGDGSPSH---PPILERTLDDVPGPP--MGILFPEVRTTSVRLI 1324
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
W P+ + IIL Y I +R +A+T + E A + + LKP + Y+FRI
Sbjct 1325 WQPPAAPNGIILAYQITHRL-NATTANTATVEVLAPSARQYMATGLKPESVYLFRITAQT 1383
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK----TLPPFEA 359
G W + + EA +T E R P + + R+V L W+ L P
Sbjct 1384 RKG---WGE-AAEALVVTTEKRDRPQPPSKPVVQQEDVKA-RSVLLSWEPGSDGLSPVRY 1438
Query 360 NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIP 417
I E+ RW H + + NA+ TV+ Y + N +G S+ + +
Sbjct 1439 Y-TIQTRELPSGRWALHSASVSHNASAFTVDRLKPFTSYKFRVKATNDIGDSEFSEESES 1497
Query 418 ACDFQAT---HPVMDLKAFPKDNM-LWVEWTTPRESVKKYIL------------------ 455
QA P + L P + + W P E IL
Sbjct 1498 LTTLQAAPDEAPTI-LSVTPHTTTSVLIRWQPPSEDKINGILLGFRIRYRELLYDGLRGF 1556
Query 456 ----------EWCVLSD-------KAPCITDWQQEDGTVHRTY-LRGNLAESKCYLITVT 497
+W L+ P +T ++ ++ + HR Y +R +++
Sbjct 1557 TLRGINNPGAKWAELTSLYSMRNLTRPSLTQYELDNLSKHRRYEIR----------MSIY 1606
Query 498 PVYADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
+GP SP + ++ +A P+ P V + + W+ P+D QNG I+ Y I
Sbjct 1607 NAVGEGPLSPPQ-EVFVGEAVPTAAPQNVAIHSATATQLDVTWEPPPLDNQNGDIQGYKI 1665
Query 557 FYRTIIGNETAVNVDS---SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKF 613
++ + V + + L +LT T YMV +AA+ G DGP +TP
Sbjct 1666 YFWEVQRRNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAG--DGPR---STPTR 1720
Query 614 AQGEIEAIVVPVCLAF--LLTTLLGV 637
Q + A P + F L TT + V
Sbjct 1721 GQTQQAAPSAPGSVKFSELTTTSVNV 1746
Score = 37.7 bits (86), Expect = 0.75, Method: Compositional matrix adjust.
Identities = 50/214 (23%), Positives = 83/214 (39%), Gaps = 14/214 (7%)
Query 397 LATLTVRNL-VGKSDA--AVLTIPACDFQATHPVMDLKAFPKD--NMLWVEWTTPRESVK 451
+ T T R L G +D+ A L + HPV L + N+ W + +
Sbjct 568 IGTYTCRVLSAGGNDSRNAHLRVRQLPHAPEHPVATLSTVERRAINLTWAKPFDGNSPLM 627
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG--SPES 509
+Y+LE + AP D ++G L ++ Y + V G G S ++
Sbjct 628 RYVLEMS--ENNAPWTILLASVDPEATSVMVKG-LVPARSYQFRLCAVNDVGKGQFSKDT 684
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVL-EWDQLPVDVQNGFIRNYTIFY---RTIIGNE 565
+ L + PP+ P N++++ +W P QNG ++ Y I Y +G +
Sbjct 685 ERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQ 744
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
D+ L L T Y + +AAY G
Sbjct 745 FKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAG 778
Score = 34.7 bits (78), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 37/147 (25%), Positives = 66/147 (45%), Gaps = 17/147 (12%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW----SQIPPEDTAS 279
P H ++ +++ E +I LTW P + +++Y ++ +A W + + PE T
Sbjct 597 PEHPVATLSTVERRAI-NLTWAKPFDGNSPLMRYVLEMSENNAP-WTILLASVDPEAT-- 652
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
S V+ L P Y FR+ + + GKG +S +E S E+ P+ P I
Sbjct 653 ---SVMVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVS--LPEEPPTAPPQ--NVIASG 705
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDY 366
T +++ + W+ P NG + Y
Sbjct 706 RTN--QSIMIQWQPPPESHQNGILKGY 730
>sp|Q5VWK5|IL23R_HUMAN Interleukin-23 receptor OS=Homo sapiens
OX=9606 GN=IL23R PE=1 SV=3
Length=629
Score = 65.5 bits (158), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 62/244 (25%), Positives = 111/244 (45%), Gaps = 18/244 (7%)
Query 78 QYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQN-VYGITIISGLPPEKPKNLSCIV 136
Q T IN+T + + + + + + C ++ + G I SG PP+ P ++C++
Sbjct 76 QITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVI 135
Query 137 NE-GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIE 195
E M C W+ G+ T+++T + + K + + ++ TS ++ ST +
Sbjct 136 YEYSGNMTCTWNAGKLTYIDTKYVVHV-----KSLETEEEQQYLTSSYINISTDSLQGGK 190
Query 196 ---VWVEAENALGKVTSD--HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
VWV+A NALG S I+ D + IN+ +I+ W S
Sbjct 191 KYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTIIY--WD--SQT 246
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
++ + ++Y+ TW+ + DT T + L+P +YVF++RC +E GK YW
Sbjct 247 TIEKVSCEMRYKATTNQTWN-VKEFDTNFTYVQQSEFYLEPNIKYVFQVRC-QETGKRYW 304
Query 311 SDWS 314
WS
Sbjct 305 QPWS 308
>sp|Q6UWB1|I27RA_HUMAN Interleukin-27 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL27RA PE=1 SV=2
Length=636
Score = 65.5 bits (158), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 103/497 (21%), Positives = 179/497 (36%), Gaps = 32/497 (6%)
Query 219 KVKPNPPH-NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
++KPN P V SE+ + W P+ S +L YR + W+ + PE
Sbjct 125 QMKPNAPRLGPDVDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLEPELK 184
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
+ +QDL+ T Y RC E + W +WS ++++ PS W +
Sbjct 185 TIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGEWSPI---LSFQTPPSAPKDVWVSGN 241
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL 397
T G L+WK A G + + W + T + +
Sbjct 242 LCGTPGGEEPLLLWK------APGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSGAEW 295
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
A ++ N L++ D + + + + L V W +++++W
Sbjct 296 ARVSAVNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDW 355
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
D + +W + L GN Y ITVT V A G S S+ + ++
Sbjct 356 ARDGDPLEKL-NWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREEL 414
Query 518 PPSKGPTV-RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
P GPT+ R + + W ++P G + +YT+ ++ +NV +
Sbjct 415 APLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQS 474
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP------KFAQGEIEAIVVPVCLAFL 630
TL L + A+ G GP P K G + + + L
Sbjct 475 VTLPDLPWGPCELWVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCGL 534
Query 631 LTTLLGVLFCFNKR-DLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFT 689
G C++ R ++ + +W VPDP+ S Q PH +Q+
Sbjct 535 SLATSG--RCYHLRHKVLPRWVWEKVPDPANSSSGQ--PHM---------EQVPEAQPLG 581
Query 690 DVSVVEIEANDKKPFPE 706
D+ ++E+E + P E
Sbjct 582 DLPILEVEEMEPPPVME 598
>sp|Q71DR4|CNTFR_CANLF Ciliary neurotrophic factor receptor subunit
alpha OS=Canis lupus familiaris OX=9615 GN=CNTFR PE=2
SV=1
Length=372
Score = 63.9 bits (154), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 56/209 (27%), Positives = 86/209 (41%), Gaps = 13/209 (6%)
Query 123 GLPPEKPKNLSCIVNE-GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
GLPP +P LSC N K C W T++ F + + K C+
Sbjct 106 GLPPREPV-LSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGS-KIMVCEKDPALKNR 163
Query 182 CTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
C + Y ++ + +V + NALG + I FD VKP+PP N+ L
Sbjct 164 CHIRYMHLFSTIKYKVSISVSNALGH-NATAITFDEFTIVKPDPPENVVARPVPSNPRRL 222
Query 241 KLTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
++TW PS LK+ ++YR W + S ++ T+ D EY+
Sbjct 223 EVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHV----ELSDGTTHTITDAYAGKEYII 278
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRP 326
++ K+ G WSDWS A + + P
Sbjct 279 QV-AAKDYEIGTWSDWSVAAHATPWTEEP 306
>sp|P51641|CNTFR_CHICK Ciliary neurotrophic factor receptor subunit
alpha OS=Gallus gallus OX=9031 GN=CNTFR PE=2 SV=1
Length=362
Score = 63.2 bits (152), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 53/208 (25%), Positives = 88/208 (42%), Gaps = 11/208 (5%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSC 182
G+PP++P + N K C W T++ +F + T + C+ C
Sbjct 104 GVPPKEPVLMCRSNNYPKGFYCSWHLPSPTYIPNSFNISVIHGTREMV-CEKDIFPKNRC 162
Query 183 TVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
+ Y ++ V +V + NALGK S + FD VKP+PP ++ L+
Sbjct 163 HIRYLQLFSTVKYKVTLTVTNALGK-NSTTLTFDEFAIVKPDPPESVVAKPVPNNPRRLE 221
Query 242 LTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
++W NPS LK+ ++YR W + D +S T+ D EY+ +
Sbjct 222 VSWQNPSSWPDPESFPLKFFLRYRPLILDQWQHVELSDG----TSHTITDAYAGKEYIIQ 277
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRP 326
+ K++ G WSDWS + + P
Sbjct 278 V-AAKDNDIGTWSDWSVAVHATPWTEEP 304
>sp|Q3UH53|SDK1_MOUSE Protein sidekick-1 OS=Mus musculus OX=10090
GN=Sdk1 PE=1 SV=1
Length=2193
Score = 64.3 bits (155), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 106/459 (23%), Positives = 178/459 (39%), Gaps = 59/459 (13%)
Query 191 FVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
FV E+ V A +G V S + + P PP L + E + +++ W P
Sbjct 1328 FVVYELQVLAFTRIGNGVPSSPLILERTKDDTPGPPVRL--VFPEVRLTAVRIVWQPPEE 1385
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ +IL Y I YR S + E A+ R FT +L P + Y+FR+ G
Sbjct 1386 PNGVILGYQIAYRLASGSPHTFTTVEVGATVRQ-FTATELAPESAYIFRLSAKTRQG--- 1441
Query 310 WSDWSE--EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
W E EA+ IT E R AP + P R+++L W +P + I +
Sbjct 1442 ---WGEPLEATVITTEKRERPAPPRELLV-PQAEVTARSLRLQW--VPGSDGASPIRYFT 1495
Query 368 VTLT-----RWKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPACD 420
V + W+++ + + AT V Y L N +G SD + T
Sbjct 1496 VQVRELPGGEWQTYSSSISHEATACAVERLRPFTSYKLRLKATNDIGDSDFSAETEAVTT 1555
Query 421 FQ--ATHPVMDLKAFPK-DNMLWVEWTTPR-ESVKKYILEWCVLSDKAPCITDWQQEDGT 476
Q P + A P + + ++W PR ES+ + + + + T E T
Sbjct 1556 LQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELESETGMSPEPKT 1615
Query 477 VHR-TYLRGNLAESKCY-------------------------LITVTPVYADGPGSPESI 510
+ + LR L + ++T + + P S +
Sbjct 1616 LKSPSALRAELTAQSSFKTVNSSSSLTTYELTHLKKYRRYEVIMTAYNIIGESPAS-VPV 1674
Query 511 KAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAV 568
+ ++ +A P+ P V+ + ++ + WD P + QNG I+ Y ++Y NET
Sbjct 1675 EVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKVYYWEADSRNETEK 1734
Query 569 NVDSSHTE--YTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
E + LTS T Y++ ++A+ G DGP+
Sbjct 1735 MKVLFLPEPVVKIKDLTSHTKYLISISAFNAAG--DGPK 1771
Score = 53.1 bits (126), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 88/400 (22%), Positives = 159/400 (40%), Gaps = 37/400 (9%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW----SQIPPEDT 277
P+PP NL S S + L+W P + +L Y +Q +++ S W S + PE T
Sbjct 650 PHPPQNLLASLSPARSHSVTLSWVRPFDGNSPVLYYIVQV-SENNSPWKVHLSNVGPEMT 708
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
TV L P Y FR+ + + GKG +S E S + + P AP K
Sbjct 709 G-----VTVSGLTPARTYQFRVCAVNQVGKG---QYSTETSRLMLPEEPPSAPP---KNI 757
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDY--EVTLTRWKSHLQNYTVNATKLTVNLTNDR 395
+ + +++ + W+ P E NG + Y L Q +++ ++ L D
Sbjct 758 VASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEHQQRNISSPEVNYCLVTDL 817
Query 396 YLATLTVRNLVGKSDA--AVLTIPACDFQ----ATHPVMDLKAFPKDN-MLWVEWTTPRE 448
+ T + + A V + ++ T P +++A ++ + W P +
Sbjct 818 IIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQAEAVNSTTVHFLWNPPPQ 877
Query 449 SVKKYI------LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD 502
I L W + + + + +H Y+ NL + Y +V
Sbjct 878 QFINGINQGYKLLAWPADAPETVTVVTIAPDFHGIHHGYIT-NLKKFTAYFTSVLCFTTP 936
Query 503 GPGSPESIK-AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI 561
G G P S + + + P + ++ + W Q P++ +NG I Y I +
Sbjct 937 GDGPPSSPQLVWTHEDKPGAVGHLSFTEILDTSLKVSW-QEPLE-RNGIIMGYQISWEVY 994
Query 562 IGNETAV--NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
N++ + ++S+ EY + L+S T Y + +AA T G
Sbjct 995 GRNDSRLTHTLNSTMHEYKIQGLSSLTTYTIDVAALTAAG 1034
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 101/457 (22%), Positives = 167/457 (37%), Gaps = 59/457 (13%)
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP 247
T Y +++ A +G TS I+ V P P NL + N S+ L+ P
Sbjct 1021 TTYTIDVAALTAA--GVGVTTSSTISSG-VPPDLPGAPSNLVISNISPRSATLQF---RP 1074
Query 248 SIKS-VIILKYNIQYRTK---DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
I ++ ++ + D W + E+ + +L P+T Y FR+R +
Sbjct 1075 GYDGKTAICRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMRQVN 1134
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
G +S S T + P AP+ S T +++L W LP + NG
Sbjct 1135 IVGPSPFSQSSRVIQ--TLQAPPDVAPTSLTVRTASET----SLRLRWVPLPDSQYNGNP 1188
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA 423
+ W+S + + +DR LT+ L + L + A +
Sbjct 1189 ESVGYRVKYWRSD------QPSSALAQVVSDRLERELTIEELE-EWTEYELRMQAFNAIG 1241
Query 424 THPVMDL----------KAFPKD--------NMLWVEWTT-PRESVKKYILEWCVLSDKA 464
P +L A P++ + + W + P + IL + VL
Sbjct 1242 AGPWSELVRGRTRESVPSAAPENVSAEAVSSTQILLTWASVPEQDQNGLILGYKVLY--- 1298
Query 465 PCITDWQQE------DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
C D E G ++ L L + Y + V G G P S +
Sbjct 1299 -CAKDLDPEPRSHVVRGNHTQSALLAGLRKFVVYELQVLAFTRIGNGVPSSPLILERTKD 1357
Query 519 PSKGPTVRT--KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSS 573
+ GP VR +V + W P + NG I Y I YR G+ T V V ++
Sbjct 1358 DTPGPPVRLVFPEVRLTAVRIVWQ--PPEEPNGVILGYQIAYRLASGSPHTFTTVEVGAT 1415
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
++T + L ++ Y+ R++A T +G + E T T
Sbjct 1416 VRQFTATELAPESAYIFRLSAKTRQGWGEPLEATVIT 1452
Score = 40.8 bits (94), Expect = 0.082, Method: Compositional matrix adjust.
Identities = 110/473 (23%), Positives = 175/473 (37%), Gaps = 84/473 (18%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA--KRDTPTSC 182
P PKN+ + + +W ET E N L+ ++ A ++ +S
Sbjct 750 PSAPPKNIVASGRTNQSIMVQWQPPPET--EHNGVLRGYILRYRLAGLPGEHQQRNISSP 807
Query 183 TVDYSTV----YFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEEL- 236
V+Y V + E+ V A N G V S + + V PP N + +E +
Sbjct 808 EVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQN---VQAEAVN 864
Query 237 SSILKLTWTNPSIKSV--IILKYNIQYRTKDAS---TWSQIPPEDTASTRSSFTVQDLKP 291
S+ + W P + + I Y + DA T I P+ T +LK
Sbjct 865 STTVHFLWNPPPQQFINGINQGYKLLAWPADAPETVTVVTIAPDFHGIHHGYIT--NLKK 922
Query 292 FTEYVFRIRCMKEDGKGYWSD----WSEEASGITYEDRPSKAP--SFWYKIDPSHTQGYR 345
FT Y + C G G S W T+ED+P SF +D S
Sbjct 923 FTAYFTSVLCFTTPGDGPPSSPQLVW-------THEDKPGAVGHLSFTEILDTS------ 969
Query 346 TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN-----YTVNATKLTVNLTNDRYLATL 400
+++ W+ P E NG I+ Y+++ W+ + +N +T+N+T + L T
Sbjct 970 -LKVSWQE--PLERNGIIMGYQIS---WEVYGRNDSRLTHTLNSTMHEYKIQGLSSLTTY 1023
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVM-----DLKAFPKDNMLWVEWTTPRESV----- 450
T+ D A LT + + DL P + L + +PR +
Sbjct 1024 TI-------DVAALTAAGVGVTTSSTISSGVPPDLPGAPSN--LVISNISPRSATLQFRP 1074
Query 451 ----KKYILEWCV------LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY 500
K I W V + D+ +T +++E+ + NL Y + V
Sbjct 1075 GYDGKTAICRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMRQVN 1134
Query 501 ADGPGSPESIKAYL---KQAPPSKGPTVRTKKVGKNEAV-LEWDQLPVDVQNG 549
GP SP S + + QAPP PT T + ++ L W LP NG
Sbjct 1135 IVGP-SPFSQSSRVIQTLQAPPDVAPTSLTVRTASETSLRLRWVPLPDSQYNG 1186
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 97/407 (24%), Positives = 156/407 (38%), Gaps = 49/407 (12%)
Query 225 PHNLSVINSEELSSILKLTWT-------NPSIKSVIILKYNIQYRTKD--ASTWSQIPPE 275
P +L+V + E S L+L W N + +SV Y ++Y D +S +Q+
Sbjct 1159 PTSLTVRTASETS--LRLRWVPLPDSQYNGNPESV---GYRVKYWRSDQPSSALAQV--- 1210
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
+ T+++L+ +TEY R++ G G WSE G T E PS AP
Sbjct 1211 VSDRLERELTIEELEEWTEYELRMQAFNAIGAG---PWSELVRGRTRESVPSAAPENVSA 1267
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT------RWKSHL--QNYTVNATKL 387
S TQ + L W ++P + NG IL Y+V +SH+ N+T +A
Sbjct 1268 EAVSSTQ----ILLTWASVPEQDQNGLILGYKVLYCAKDLDPEPRSHVVRGNHTQSALLA 1323
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE--WTT 445
+ L L + ++ L + P + L FP+ + V W
Sbjct 1324 GLRKFVVYELQVLAFTRIGNGVPSSPLILERTKDDTPGPPVRL-VFPEVRLTAVRIVWQP 1382
Query 446 PRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD 502
P E + Y + + + S T E G R + LA Y+ ++
Sbjct 1383 PEEPNGVILGYQIAYRLASGSPHTFTT--VEVGATVRQFTATELAPESAYIFRLSAKTRQ 1440
Query 503 GPGSP---ESIKAYLKQAP-PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
G G P I ++ P P + V +V L+W +P IR +T+
Sbjct 1441 GWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQW--VPGSDGASPIRYFTVQV 1498
Query 559 RTIIGNE---TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
R + G E + ++ T + L T Y +R+ A D G D
Sbjct 1499 RELPGGEWQTYSSSISHEATACAVERLRPFTSYKLRLKATNDIGDSD 1545
>sp|Q810U4|NRCAM_MOUSE Neuronal cell adhesion molecule OS=Mus
musculus OX=10090 GN=Nrcam PE=1 SV=2
Length=1256
Score = 64.3 bits (155), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 100/417 (24%), Positives = 164/417 (39%), Gaps = 56/417 (13%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYR--TKDASTWSQIP 273
P+Y V PNPP +L + N +L ++LTWT + I K+ I+Y DA W
Sbjct 636 PIYDV-PNPPFDLELTN--QLDKSVQLTWTPGDDNNSPITKFIIEYEDAMHDAGLWRH-- 690
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
+ + T+++ ++ L P+ Y FR+ G+ S+ SE+ +T P +
Sbjct 691 QAEVSGTQTTAQLK-LSPYVNYSFRVMAENSIGRSMPSEASEQY--LTKAAEPDQ----- 742
Query 334 YKIDPSHTQGYRT----VQLVWKTLPPFEANGKILDYEVTLTR------WKS----HLQN 379
+P +G T + + WK L F++NG L Y+V+ + W S ++
Sbjct 743 ---NPMAVEGLGTEPDNLVITWKPLNGFQSNGPGLQYKVSWRQKDGDDEWTSVVVANVSK 799
Query 380 YTVNATKLTVNLTNDRYLATLTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDN 437
Y V+ T V YL + N VG AAV+ D P +
Sbjct 800 YIVSGTPTFV-----PYLIKVQALNDVGFAPEPAAVMGHSGEDLPMVAPGNVRVSVVNST 854
Query 438 MLWVEWT-TPRESVKKY-----ILEWCVLSDKAPCITDWQQEDGTVHRTYLRG---NLAE 488
+ V W P +SV+ + I W S +++ T T G L
Sbjct 855 LAEVHWDPVPPKSVRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGTKTHGMLPGLQP 914
Query 489 SKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
Y + V V G G + + + + PS +++ + LEWD P
Sbjct 915 YSHYALNVRVVNGKGEGPASTDRGFHTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHP 972
Query 548 NGFIRNYTIFYRTI-----IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
NG + Y + Y+ I +G + + ++ T +TL +L T Y A T G
Sbjct 973 NGILTEYILQYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSVG 1029
>sp|A2ABU4|MYOM3_MOUSE Myomesin-3 OS=Mus musculus OX=10090 GN=Myom3
PE=1 SV=1
Length=1439
Score = 63.9 bits (154), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 114/494 (23%), Positives = 184/494 (37%), Gaps = 55/494 (11%)
Query 132 LSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF 191
+ C+ G RC G E F ++ A K + + T DY V+
Sbjct 421 MPCLKAPGGTCRCPIQGLVEGQ-SYQFRVR---AISKAGTSLPSKASEAVVTGDYDAVHK 476
Query 192 VNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
E LG K+T +F+ + P+ P N+ E ++L +W P +
Sbjct 477 ST-----EIPYDLGSKITISKNDFEDAVTI-PSAPTNVHASEIREAYAVL--SWEEPRPR 528
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
L Y ++ + TW I E T F + DL+ YVFR+R + + G
Sbjct 529 GRAPLTYTLEKSVIGSGTWEAISTE-TPIKSPRFALLDLEKGKSYVFRVRALNQYGM--- 584
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR----TVQLVWKTLPPFEANGKILDY 366
SD SE + + + +P+ P P+ Q +R +V L W+ P + ++L Y
Sbjct 585 SDPSEPSEPVALKGKPATLPP------PAQVQAFRNTQTSVSLAWE---PVDGGSELLGY 635
Query 367 -----EVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNL----VGKSDAAVLTIP 417
E + W++ + N + TK TV +R++ VG+S AA +
Sbjct 636 YIYSREAGASEWQT-VNNKPIQDTKFTVPGLRTGKEYDFCIRSVSEAGVGESSAATQPVR 694
Query 418 ACDFQATHPV---MDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ--Q 472
AT L K+ M+ + W P+ IL + + +DW
Sbjct 695 VKQALATPSAPYDFALLNCGKNEMV-IGWKPPKRRGGGKILGY-FMDQHDSVESDWHPVN 752
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPG---SPESIKAYLKQAPPSKGP--TVRT 527
R NL E Y V G G +P S+ + P GP VR
Sbjct 753 RQPIPSRVCKVTNLHEGHFYEFRARAVNWAGIGELSAPSSLFECKEWTMPEPGPPYDVRV 812
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDS-SHTEYTLSSLTSD 585
+V +L+W+ P+ + G + Y + ++ E V D+ S T +S L
Sbjct 813 SEVQATSVMLQWEP-PLYIGAGPVTGYHVSFQEKGSEEWKPVTPDATSDTHLRVSDLQPG 871
Query 586 TLYMVRMAAYTDEG 599
YM R+ A G
Sbjct 872 KQYMFRVQAMNSAG 885
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 26/89 (29%), Positives = 48/89 (54%), Gaps = 5/89 (6%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
+P PP+++ V SE ++ + L W P I + + Y++ ++ K + W + P+ T+
Sbjct 803 EPGPPYDVRV--SEVQATSVMLQWEPPLYIGAGPVTGYHVSFQEKGSEEWKPVTPDATSD 860
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
T V DL+P +Y+FR++ M G G
Sbjct 861 TH--LRVSDLQPGKQYMFRVQAMNSAGLG 887
>sp|A4IFW2|PTPRF_DANRE Receptor-type tyrosine-protein phosphatase
F OS=Danio rerio OX=7955 GN=ptprf PE=2 SV=1
Length=1909
Score = 63.5 bits (153), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 103/417 (25%), Positives = 168/417 (40%), Gaps = 64/417 (15%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
K P PP +L+V +E ++ + LTW + + + V Y IQYR K + T Q + A
Sbjct 317 KALPKPPTSLTV--TETTATSVTLTWDSGNPEPVSY--YIIQYRAKTSDTNFQ-EVDGVA 371
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+TR +++ L P++EY FR+ + G+G S+ E +G E PS P
Sbjct 372 TTR--YSIGGLSPYSEYEFRVMAVNNIGRGPPSEPVETRTG---EQAPSSP--------P 418
Query 339 SHTQGY----RTVQLVWKTLPPFEANGKILDYEV--------TLTRWKSHLQNYT--VNA 384
H Q T+ + W+ PP E NG+I Y + L+ W+ H + +
Sbjct 419 LHVQARMLSASTMLVQWE--PPEEPNGQIRGYRIYYTSDLDAPLSAWQKHNTDDSRLTTI 476
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
+ LT +T L L ++ + VL + P D + + W
Sbjct 477 SSLTTGITYS--LRVLGFTSVGDGPPSDVLQVKTQQGVPAQPSSFEAEAELDTRILLTWL 534
Query 445 TP-RESVKKYILEWCVLSDKAPCITDWQQE-DGTVHRT------YLRGNLAESKCYLITV 496
P ++ + KY L++ W+ + D +H T Y L Y ++
Sbjct 535 WPVQDPIIKYELQY------------WEADSDNKIHVTFDPAGSYAVEGLKPDTLYKFSL 582
Query 497 TPVYADGPGS-PESIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
G G I+A Q+ PS P V + + W P ++G I Y
Sbjct 583 AARSEMGQGVFTHPIEARTAQSAPSAPPQDVHLLSLSSTSIKVSWVAPPAASRHGAIVRY 642
Query 555 TIFYRTIIGNET----AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
T+ Y+ + G +T ++ + + L L T Y V + A+TD G GPE T
Sbjct 643 TVSYQAVNGEDTERHEVPDIGADASSCVLEGLEKWTEYQVWVRAHTDVG--PGPEST 697
Score = 57.4 bits (137), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 94/427 (22%), Positives = 167/427 (39%), Gaps = 83/427 (19%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSV--IILKYNIQYRTKDASTWSQIPPEDTASTR 281
PP ++ +++ S+ +K++W P S I++Y + Y+ + + D +
Sbjct 609 PPQDVHLLSLS--STSIKVSWVAPPAASRHGAIVRYTVSYQAVNGEDTERHEVPDIGADA 666
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI---TYEDRPSKAPSFWYKIDP 338
SS ++ L+ +TEY +R + G G E++ + T ED P AP +++
Sbjct 667 SSCVLEGLEKWTEYQVWVRAHTDVGPG------PESTAVRIRTNEDVPG-APPRKLEVEA 719
Query 339 SHTQGYRTVQLVWKTLPPFEA--NGKILDYEVTLTR---------------------WK- 374
++ R + WK PP +G+I Y+V +R WK
Sbjct 720 LNSTAIR---VTWK--PPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVALPEAQWKI 774
Query 375 SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP 434
Y L + +A T + +S A V+T P M +
Sbjct 775 EESTEYEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTTGA--VPGKPTMIISTTV 832
Query 435 KDNMLWVEWTTPRESVKK---YILEWCVLSDKAPCITDWQQED----------GTVHRTY 481
+ L ++W P++ V + Y L + L ++ I ++ + D G + +
Sbjct 833 GNTAL-IQWQPPKDMVGELMGYRLRYKRLEEENYEIREFSRTDDHHTVTDLHKGATYSFH 891
Query 482 L----RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVL 537
L R L E Y G+PE + + G T T + L
Sbjct 892 LSARNRAGLGEE----------YVKDIGTPEDVPSGFPLNLQVVGLTTSTTR-------L 934
Query 538 EWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
W+ + +NG I +Y + YR I + + N +S T+ T+ L DT Y +R+ A+T
Sbjct 935 TWEPPALSERNGRIIHYIVVYRDINSKQNSTN-RTSDTQMTIQGLRPDTTYDIRVQAFTS 993
Query 598 EGGKDGP 604
+GG GP
Sbjct 994 KGG--GP 998
>sp|Q58EX2|SDK2_HUMAN Protein sidekick-2 OS=Homo sapiens OX=9606
GN=SDK2 PE=1 SV=3
Length=2172
Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 112/468 (24%), Positives = 178/468 (38%), Gaps = 78/468 (17%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P PP + ++ E ++ ++L W P+ + IIL Y I +R + + E A +
Sbjct 1301 PGPP--MGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTA-NTATVEVLAPSA 1357
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+T LKP + Y+FRI G W + + EA +T E R P +
Sbjct 1358 RQYTATGLKPESVYLFRITAQTRKG---WGE-AAEALVVTTEKRDRPQPPSRPMVQQEDV 1413
Query 342 QGYRTVQLVWK----TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN--DR 395
+ R+V L W+ L P I E+ RW H + + NA+ V+
Sbjct 1414 RA-RSVLLSWEPGSDGLSPVRYY-TIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTS 1471
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQAT---HPVMDLKAFPKDNM-LWVEWTTPRESVK 451
Y + N +G S+ + + QA P + L P + + W P E
Sbjct 1472 YKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI-LSVTPHTTTSVLIRWQPPAEDKI 1530
Query 452 KYIL----------------------------EWCVLSD-------KAPCITDWQQEDGT 476
IL W L+ P +T ++ ++
Sbjct 1531 NGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLN 1590
Query 477 VHRTY-LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNE 534
HR Y +R ++V +GP SP + ++ +A P+ P V +
Sbjct 1591 KHRRYEIR----------MSVYNAVGEGPSSPPQ-EVFVGEAVPTAAPRNVVVHGATATQ 1639
Query 535 AVLEWDQLPVDVQNGFIRNYTI-FYRTIIGN--ETAVNVDSSHTEYTLSSLTSDTLYMVR 591
+ W+ P+D QNG I+ Y I F+ GN E + + L +LT T YMV
Sbjct 1640 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVS 1699
Query 592 MAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAF--LLTTLLGV 637
+AA+ G DGP +TP Q + A P + F L TT + V
Sbjct 1700 VAAFNAAG--DGPR---STPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742
Score = 41.6 bits (96), Expect = 0.039, Method: Compositional matrix adjust.
Identities = 53/196 (27%), Positives = 85/196 (43%), Gaps = 24/196 (12%)
Query 180 TSCTVDYSTVYFVNIEV-----WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
T+ + +VY I W EA AL VT++ + +P PP V +
Sbjct 1361 TATGLKPESVYLFRITAQTRKGWGEAAEAL-VVTTEK-------RDRPQPPSRPMVQQED 1412
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ + L+W S + Y IQ R + W+ + + SSF V LKPFT
Sbjct 1413 VRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWA-LHSASVSHNASSFIVDRLKPFTS 1471
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y FR++ + G +S+ SE + T + P +AP+ + P T +V + W+
Sbjct 1472 YKFRVKATNDIGDSEFSEESESLT--TLQAAPDEAPTI-LSVTPHTTT---SVLIRWQ-- 1523
Query 355 PPFE--ANGKILDYEV 368
PP E NG +L + +
Sbjct 1524 PPAEDKINGILLGFRI 1539
Score = 41.6 bits (96), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 112/464 (24%), Positives = 162/464 (35%), Gaps = 78/464 (17%)
Query 194 IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI 253
IEV G+V++ I+ V P PP NL + N S L+ S+
Sbjct 966 IEVAAMTSKGQGQVSASTISSG-VPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSIS 1024
Query 254 ILKYNIQYRT-KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
Q + W I S V DL PFT Y FR+R + G S
Sbjct 1025 RWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQ 1084
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG--KILDYEVTL 370
S + T + P AP+ S T ++ L W LP E NG + + Y++
Sbjct 1085 PSRKIQ--TLQAPPDMAPANVSLRTASET----SLWLRWMPLPEMEYNGNPESVGYKIKY 1138
Query 371 TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNL------------------------- 405
+R H K ++ DR T+ +L
Sbjct 1139 SRSDGH--------GKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTV 1190
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT-TPRESVKKYILEWCVL---- 460
VG++ +V + + A A +ML V W+ P +L + V+
Sbjct 1191 VGRTRESVPSSGPTNVSAL-------ATTSSSML-VRWSEVPEADRNGLVLGYKVMYKEK 1242
Query 461 -SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES---IKAYLKQ 516
SD P W E + L G L + Y + V G GSP ++ L
Sbjct 1243 DSDTQPRF--WLVEGNSSRSAQLTG-LGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDD 1299
Query 517 AP-PSKG---PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD- 571
P P G P VRT V L W P NG I Y I +R V+
Sbjct 1300 VPGPPMGILFPEVRTTSVR-----LIWQ--PPAAPNGIILAYQITHRLNTTTANTATVEV 1352
Query 572 --SSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPK 612
S +YT + L +++Y+ R+ A T +G G+ TT K
Sbjct 1353 LAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEK 1396
Score = 39.3 bits (90), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 93/428 (22%), Positives = 160/428 (37%), Gaps = 89/428 (21%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI---QYRTKDASTWSQIPPEDTA 278
P P +LS SE L + LK++W P K+ I+ Y I +Y + +P
Sbjct 895 PGPVGHLSF--SEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLP----- 947
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+ + V L T Y + M G+G S S +SG+ P + P +
Sbjct 948 NVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSA-STISSGV-----PPELPGPPTNLGI 1001
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK---LTVNLTNDR 395
S+ G R+V L ++ P + D + +++RW Q V + L L+N+
Sbjct 1002 SNI-GPRSVTLQFR--PGY-------DGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEP 1051
Query 396 YLATLTVR---------------NLVGKSDAAVLTIPACDFQATHPVMDLKAFP------ 434
++ V N+VG S + Q + + L+A P
Sbjct 1052 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPS---------QPSRKIQTLQAPPDMAPAN 1102
Query 435 ------KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG-----------TV 477
+ LW+ W E +E+ + + + DG V
Sbjct 1103 VSLRTASETSLWLRWMPLPE------MEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV 1156
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPT-VRTKKVGKNEA 535
R Y +L E Y + V A G G +++ +++ PS GPT V +
Sbjct 1157 ERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSM 1216
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA----VNVDSSHTEYTLSSLTSDTLYMVR 591
++ W ++P +NG + Y + Y+ + V +SS + L+ L LY V+
Sbjct 1217 LVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSA-QLTGLGKYVLYEVQ 1275
Query 592 MAAYTDEG 599
+ A+T G
Sbjct 1276 VLAFTRIG 1283
Score = 37.4 bits (85), Expect = 0.99, Method: Compositional matrix adjust.
Identities = 37/143 (26%), Positives = 66/143 (46%), Gaps = 9/143 (6%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P H ++ +++ E +I LTWT P + +++Y ++ +A + D +T S
Sbjct 593 PEHPVATLSTVERRAI-NLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKAT--S 649
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
TV+ L P Y FR+ + + GKG +S +E S E+ P+ P I T
Sbjct 650 VTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVS--LPEEPPTAPPQ--NVIASGRTN- 704
Query 344 YRTVQLVWKTLPPFEANGKILDY 366
+++ + W+ P NG + Y
Sbjct 705 -QSIMIQWQPPPESHQNGILKGY 726
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 46/199 (23%), Positives = 76/199 (38%), Gaps = 11/199 (6%)
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKD--NMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
S +A L + HPV L + N+ W + + +YILE + AP
Sbjct 579 SRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMS--ENNAPW 636
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG--SPESIKAYLKQAPPSKGPT 524
D ++G L ++ Y + V G G S ++ + L + PP+ P
Sbjct 637 TVLLASVDPKATSVTVKG-LVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQ 695
Query 525 VRTKKVGKNEAVL-EWDQLPVDVQNGFIRNYTIFYRTI---IGNETAVNVDSSHTEYTLS 580
N++++ +W P QNG ++ Y I Y +G + D+ L
Sbjct 696 NVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLE 755
Query 581 SLTSDTLYMVRMAAYTDEG 599
L T Y + +AAY G
Sbjct 756 DLIIWTNYEIEVAAYNSAG 774
>sp|P97686|NRCAM_RAT Neuronal cell adhesion molecule OS=Rattus
norvegicus OX=10116 GN=Nrcam PE=1 SV=2
Length=1214
Score = 62.4 bits (150), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 97/418 (23%), Positives = 167/418 (40%), Gaps = 58/418 (14%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYR--TKDASTWSQIP 273
P+Y V PNPP +L + N +L ++LTWT + I K+ I+Y +A W
Sbjct 642 PIYDV-PNPPFDLELTN--QLDKSVQLTWTPGDDNNSPITKFIIEYEDAMHEAGLWRH-- 696
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
+ + T+++ ++ L P+ Y FR+ G+ S+ SE+ +T P +
Sbjct 697 QAEVSGTQTTAQLK-LSPYVNYSFRVMAENSIGRSVPSEASEQY--LTKAAEPDQ----- 748
Query 334 YKIDPSHTQGYRT----VQLVWKTLPPFEANGKILDYEVTLTR------WKS----HLQN 379
+P+ +G T + + WK L F++NG L Y+V+ + W S ++
Sbjct 749 ---NPTAVEGLGTEPDNLVITWKPLNGFQSNGPGLQYKVSWRQKDGDDEWTSVVVANVSK 805
Query 380 YTVNATKLTVNLTNDRYLATLTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDN 437
Y V+ T V YL + N VG AAV+ D P +
Sbjct 806 YIVSGTPTFV-----PYLIKVQALNDVGFAPEPAAVMGHSGEDLPMVAPGNVRVSVVNST 860
Query 438 MLWVEW-TTPRESVKKYILEWCVLSDKAPCITDWQQE---------DGTVHRTYLRGNLA 487
+ W P +SV+ ++ + + KA + + G+ L G L
Sbjct 861 LAEAHWDPVPPKSVRGHLQGYRIYYWKAQSSSKRNRRHIEKKILTFQGSKTHGMLPG-LQ 919
Query 488 ESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDV 546
Y++ V V G G + + + + PS +++ + LEWD P
Sbjct 920 PYSHYVLNVRVVNGKGEGPASADRGFHTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSH 977
Query 547 QNGFIRNYTIFYRTI-----IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
NG + Y + Y+ I +G + + ++ T +TL +L T Y A T G
Sbjct 978 PNGILTEYILKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSVG 1035
>sp|Q92823|NRCAM_HUMAN Neuronal cell adhesion molecule OS=Homo
sapiens OX=9606 GN=NRCAM PE=1 SV=3
Length=1304
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 108/448 (24%), Positives = 177/448 (40%), Gaps = 65/448 (15%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPE 275
PVY V PNPP +L + +++L ++L+WT + I K+ I+Y +DA +
Sbjct 642 PVYDV-PNPPFDLEL--TDQLDKSVQLSWTPGDDNNSPITKFIIEY--EDAMHKPGLWHH 696
Query 276 DTASTRSSFTVQ-DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
T + + T Q L P+ Y FR+ + GK S+ SE+ +T P K
Sbjct 697 QTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQY--LTKASEPDK------ 748
Query 335 KIDPSHTQGYRT----VQLVWKTLPPFEANGKILDYEVTLTR------WKS----HLQNY 380
+P+ +G + + + WK L FE+NG L Y+V+ + W S ++ Y
Sbjct 749 --NPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANVSKY 806
Query 381 TVNATKLTVNLTNDRYLATLTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
V+ T V YL + N +G A V+ D P +
Sbjct 807 IVSGTPTFV-----PYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTL 861
Query 439 LWVEWT-TPRESVKKY-----ILEWCVLSDKAPCITDWQQEDGTVHRTYLRG---NLAES 489
V W P +S++ + I W S +++ T + G L
Sbjct 862 AEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPF 921
Query 490 KCYLITVTPV--YADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
Y + V V +GP SP+ + + PS +++ + LEWD P
Sbjct 922 SHYTLNVRVVNGKGEGPASPDRV-FNTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHP 978
Query 548 NGFIRNYTIFYRTI-----IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GK 601
NG + YT+ Y+ I +G + + ++ T +TL +L T Y A T G G
Sbjct 979 NGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGS 1038
Query 602 DGPEFTFTT--------PKFAQGEIEAI 621
E TT P G+++A+
Sbjct 1039 QITEEAVTTVDEAGILPPDVGAGKVQAV 1066
>sp|Q8IWV2|CNTN4_HUMAN Contactin-4 OS=Homo sapiens OX=9606 GN=CNTN4
PE=1 SV=1
Length=1026
Score = 58.9 bits (141), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 97/463 (21%), Positives = 170/463 (37%), Gaps = 62/463 (13%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP- 273
D + + P PP +++ E + +L+W I Y IQ RT + W +
Sbjct 590 DLIVRGPPGPPEAVTI--DEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVST 647
Query 274 -PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF 332
PE + TV L P+ EY FR G G S SE+ T E P P+
Sbjct 648 VPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRR--TEEALPEVTPA- 704
Query 333 WYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT------ 385
+ S G ++ + + W+T+P NG+ Y V + + TV A+
Sbjct 705 ----NVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRY 760
Query 386 -------------KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA 432
++ V + N++ + +V ++ PA F + D++
Sbjct 761 VFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEV 820
Query 433 FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG-------- 484
F W +P E + I + V W+ ED + +R
Sbjct 821 F---------WASPLEKNRGRIQGYEV--------KYWRHEDKEENARKIRTVGNQTSTK 863
Query 485 --NLAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
NL S Y + V + G G S ++ ++ PPS+ P ++ +L WDQ
Sbjct 864 ITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQ 923
Query 542 LPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
+ ++ Y + YR + T+V ++++ T L SL D Y++ + ++D GG
Sbjct 924 VKALDNESEVKGYKVLYRWNRQSSTSV-IETNKTSVEL-SLPFDEDYIIEIKPFSD-GGD 980
Query 602 DGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
PK + A L+ + ++ R
Sbjct 981 GSSSEQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTAR 1023
>sp|P29322|EPHA8_HUMAN Ephrin type-A receptor 8 OS=Homo sapiens
OX=9606 GN=EPHA8 PE=1 SV=2
Length=1005
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 58/210 (28%), Positives = 84/210 (40%), Gaps = 20/210 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADC-KAKRDT 178
PP P NL VN G + EW GGR + WA + C R
Sbjct 328 PPSAPVNLISSVN-GTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGTRFV 386
Query 179 PTSCTVDYSTVYFVNI------EVWVEAENALGKVTSDHINFDPVYKVKPN--PPHNLSV 230
P ++ +++ N+ W+EA N + ++ + V + N P + V
Sbjct 387 PQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEP-RRAAVVNITTNQAAPSQVVV 445
Query 231 INSEELSSI-LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
I E + L W P + IIL+Y I+Y KD S +TR+ TV L
Sbjct 446 IRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQS-YSTLKAVTTRA--TVSGL 502
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
KP T YVF++R G G +S E +G
Sbjct 503 KPGTRYVFQVRARTSAGCGRFSQAMEVETG 532
Score = 34.7 bits (78), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 8/134 (6%)
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL-----KQAPPSKGPTVR 526
Q+ V + L NL Y + V SPE +A + QA PS+ +R
Sbjct 388 QQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIR 447
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
++ G+ L W + + NG I Y I +Y ++ + + T T+S L
Sbjct 448 QERAGQTSVSLLWQE--PEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPG 505
Query 586 TLYMVRMAAYTDEG 599
T Y+ ++ A T G
Sbjct 506 TRYVFQVRARTSAG 519
>sp|O09127|EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus musculus
OX=10090 GN=Epha8 PE=1 SV=2
Length=1004
Score = 58.2 bits (139), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 59/210 (28%), Positives = 86/210 (41%), Gaps = 20/210 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWA-THKFADCKAKRDT 178
PP P NL VN G + EW GGR + WA +H A R
Sbjct 327 PPSAPVNLISSVN-GTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSHCEACGSGTRFV 385
Query 179 PTSCTVDYSTVYFVNI------EVWVEAENALGKVTSDHINFDPVYKVKPN--PPHNLSV 230
P ++ +++ N+ W+EA N + ++ + + V + N P + V
Sbjct 386 PQQTSLAQASLLVANLLAHMNYSFWIEAVNGVSNLSPEPRS-AAVVNITTNQAAPSQVVV 444
Query 231 INSEELSSI-LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
I E + L W P + IIL+Y I+Y KD S +TR+ TV L
Sbjct 445 IRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQS-YSTLKAVTTRA--TVSGL 501
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
KP T YVF++R G G +S E +G
Sbjct 502 KPGTRYVFQVRARTSAGCGRFSQAMEVETG 531
>sp|Q5VTT5|MYOM3_HUMAN Myomesin-3 OS=Homo sapiens OX=9606 GN=MYOM3
PE=1 SV=1
Length=1437
Score = 57.4 bits (137), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 88/357 (25%), Positives = 139/357 (39%), Gaps = 35/357 (10%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P+PP N+ SE + + L W PS + L Y+++ + TW I E +
Sbjct 501 PSPPTNVHA--SEIREAYVVLAWEEPSPRDRAPLTYSLEKSVIGSGTWEAISSESPVRS- 557
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
F V DL+ YVFR+R M + G SD SE + I P+ P P+
Sbjct 558 PRFAVLDLEKKKSYVFRVRAMNQYG---LSDPSEPSEPIALRGPPATLPP------PAQV 608
Query 342 QGYR----TVQLVWKTLPPFEANG-KILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRY 396
Q +R +V L W + E G I +V + W++ + N + T+ TV
Sbjct 609 QAFRDTQTSVSLTWDPVKDPELLGYYIYSRKVGTSEWQT-VNNKPIQGTRFTVPGLRTGK 667
Query 397 LATLTVRNL----VGKSDAAVLTIPACDFQATHPV---MDLKAFPKDNMLWVEWTTPRES 449
VR++ VG+S AA I AT L K+ M+ + W P+
Sbjct 668 EYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMV-IGWKPPKRR 726
Query 450 VKKYILEWCVLSDKAPCITDWQ--QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-- 505
IL + + + + DW + R +L E Y G G
Sbjct 727 GGGKILGYFLDQHDSEEL-DWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGEL 785
Query 506 -SPESIKAYLKQAPPSKGP--TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
+P S+ + P GP VR +V VL+W+ P+ + G + Y + ++
Sbjct 786 SAPSSLFECKEWTMPQPGPPYDVRASEVRATSLVLQWEP-PLYMGAGPVTGYHVSFQ 841
Score = 38.9 bits (89), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 23/89 (26%), Positives = 44/89 (49%), Gaps = 5/89 (6%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
+P PP+++ SE ++ L L W P + + + Y++ ++ + + W + P +
Sbjct 801 QPGPPYDVRA--SEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISG 858
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
T V DL+P YVF+++ M G G
Sbjct 859 TH--LRVSDLQPGKSYVFQVQAMNSAGLG 885
>sp|Q99MF4|I11RA_RAT Interleukin-11 receptor subunit alpha OS=Rattus
norvegicus OX=10116 GN=Il11ra1 PE=2 SV=1
Length=431
Score = 56.2 bits (134), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 54/224 (24%), Positives = 89/224 (40%), Gaps = 27/224 (12%)
Query 114 NVYG--ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFAD 171
V+G +T+ G PP +P+ +SC + + C W GR + L T + + +
Sbjct 99 GVFGGMVTLKLGSPPARPE-VSCQAVDYENFSCTWSPGRVSGLPTRYL--TSYRKKTLPG 155
Query 172 CKAKRDTPTS----CTVD---YSTVYFVNIEVWVEAE------NALGKVTSDHINFDPVY 218
+++R++P++ C D S E W E N LG T ++
Sbjct 156 AESQRESPSTGPWPCPQDPLEASRCVVHGAEFWSEYRINVTEVNPLGASTC-LLDVRLQR 214
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPE 275
++P+PP L V + L +WT P+ + +LK+ +QYR WS + P
Sbjct 215 ILRPDPPQGLRVESVPGYPRRLHASWTYPASWRRQPHFLLKFRLQYRPAQHPAWSTVEPI 274
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ D + R+ G WS WS EA G
Sbjct 275 GLEE-----LITDAVAGLPHAVRVSARDFLDAGTWSAWSPEAWG 313
>sp|O94779|CNTN5_HUMAN Contactin-5 OS=Homo sapiens OX=9606 GN=CNTN5
PE=1 SV=2
Length=1100
Score = 56.6 bits (135), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 105/446 (24%), Positives = 184/446 (41%), Gaps = 61/446 (14%)
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELS-SILKLTWTNPSIKSVIILKYNIQYRTK 264
+ T+D ++ + V+ PP ++ EE++ S L+W+ + I YN+Q R+
Sbjct 653 QTTADSVSDEAELLVR-GPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSP 711
Query 265 DASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI-T 321
+ W + PE S DL P+ EY FR+ G G D S + I T
Sbjct 712 FSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTG---DPSTPSRMIRT 768
Query 322 YEDRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTL----TR-WKS 375
E P AP+ + S G R + + W+ + NG+ Y V TR WK
Sbjct 769 NEAVPKTAPT-----NVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKE 823
Query 376 HLQNYTVNATKLTVNLTNDRYLATLT-------VRNLVGKSD-AAVLTIPACDFQATHPV 427
+ V +++ + + D + LT V N G + ++ I + + + +
Sbjct 824 KM----VTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAP 879
Query 428 MDLKAFPKD-NMLWVEWTTPRESVKK----YILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
D+KA + + V W +ES+ + + W D +QED T
Sbjct 880 TDVKATSVSVSEILVAWKHIKESLGRPQGFEVGYW----------KDMEQED-TAETVKT 928
Query 483 RGN--------LAESKCYLITVTPVYADGPGSPES-IKAYLKQAPPSKGPT-VRTKKVGK 532
RGN L + Y TV G G P S + A K++PPS+ P+ +R ++ G
Sbjct 929 RGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWEQQG- 987
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
++ L W+ + + Y +FYR G+ + +++ + + L +Y++ +
Sbjct 988 SQVSLGWEPVIPLANESEVVGYKVFYRQ-EGHSNSQVIETQKLQAVV-PLPDAGVYIIEV 1045
Query 593 AAYTDEGGKDGPEFTFTTPKFAQGEI 618
AY+ EGG P ++ G+I
Sbjct 1046 RAYS-EGGDGTASSQIRVPSYSGGKI 1070
>sp|P08887|IL6RA_HUMAN Interleukin-6 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL6R PE=1 SV=1
Length=468
Score = 55.5 bits (132), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 57/230 (25%), Positives = 103/230 (45%), Gaps = 31/230 (13%)
Query 118 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 174
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
Query 175 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 222
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
Query 223 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
+ + D +V ++R +E G+G WS+WS EA G + + S++P
Sbjct 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTE--SRSP 321
>sp|Q9N3X8|SDK_CAEEL Protein sidekick homolog OS=Caenorhabditis
elegans OX=6239 GN=rig-4 PE=1 SV=2
Length=2325
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 114/466 (24%), Positives = 185/466 (40%), Gaps = 66/466 (14%)
Query 191 FVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
F + EV V +EN G+ + +D + V P N+ V ++I+K W NP
Sbjct 1225 FTSYEVNVFSENGFGRSLPTDSVKARTYESVPSGSPRNIVVTAEGSKAAIIK--W-NPVA 1281
Query 250 K-----SVIILKYNI----QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
+ VI K + + D + IP + T + V DL+PFT Y +
Sbjct 1282 ELSTNGDVIGYKLRVVPERESLMADETKVIDIPGQSTLMAK----VSDLRPFTSYHVYMS 1337
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
G G + S S T ED P+ SF + V++ W LPP N
Sbjct 1338 AYTIVGNG--PENSTPISFETMEDVPAPPESF-----QCSYISEQEVRMKW--LPPGSPN 1388
Query 361 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLT---------NDRYLATLTVRNLVGKSDA 411
GKI +Y ++ WKSH L NL N +Y + RN G+S+
Sbjct 1389 GKITNY--IISYWKSHEPRSMAIDAPLLGNLLMFAAMSLNPNTQYTFAIKARNSKGESEE 1446
Query 412 AVLTIPACDFQ-----ATHPVMDLKAFPKDNMLWVEW--TTPR------ESVKKYILEWC 458
AV + + A PV D + + + + W + PR ES + +
Sbjct 1447 AVAEVMTSSVRLPVRNAPAPVRDTLSQHQATEIIIRWDESLPRKLTEDAESPVRAVQVSY 1506
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPV--YADGPGSPES-IKAYLK 515
+++ IT ++ + + R+ ++ +L+ + + + + + + SPES L
Sbjct 1507 QKTNEDEWITLEKKFEYSKRRSVIK-HLSPNSMFRFRIRFIGDFLESSWSPESEWMRTLP 1565
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET----AVNVD 571
AP ++ +++ +N LEW N Y I YR NET + +
Sbjct 1566 SAPFAQPISLKATPYERNSVQLEWVVPHKSTWNSDAIGYRIHYREYPSNETWQMEEIAIR 1625
Query 572 SSH---TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFA 614
H E L+ L S Y++RM + EG +GP F+ P FA
Sbjct 1626 DEHEDKEEKILAKLDSFKHYILRMRIFNSEG--EGP---FSAPVFA 1666
Score = 40.0 bits (92), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 33/115 (29%), Positives = 51/115 (44%), Gaps = 11/115 (10%)
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSS-FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y I YR D W ++ T + RSS TV DL+PFT Y + E+G G S ++
Sbjct 1192 YLIVYREIDDENWKEV---RTPALRSSEHTVTDLRPFTSY--EVNVFSENGFGR-SLPTD 1245
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
TYE PS +P +G + + W + NG ++ Y++ +
Sbjct 1246 SVKARTYESVPSGSPRNIVVT----AEGSKAAIIKWNPVAELSTNGDVIGYKLRV 1296
Score = 35.4 bits (80), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 39/169 (23%), Positives = 68/169 (40%), Gaps = 29/169 (17%)
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
LW +WTT +++ K + C C TD + +L S V
Sbjct 691 LWSDWTTAIDNIPKEEGKPC-------CWTDIE-------------DLRPSSTAEFRVVA 730
Query 499 VYADGPGSPESIKAY---LKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
GPG P S+ +Y + Q PPS P V + +++W Q ++ +G + Y
Sbjct 731 SNKHGPGKP-SLPSYSVTMPQQPPSAAPRNVAASARSPHSVMVQWQQPKEELDSGDVLGY 789
Query 555 TIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTL----YMVRMAAYTDEG 599
+ YR + N + T+ ++L + + Y +++AAY G
Sbjct 790 VVRYRLAGYSSLTWNEKNLTTKDARNTLVDELITWREYEIQVAAYNKRG 838
>sp|P22273|IL6RA_RAT Interleukin-6 receptor subunit alpha OS=Rattus
norvegicus OX=10116 GN=Il6r PE=2 SV=2
Length=462
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 61/259 (24%), Positives = 109/259 (42%), Gaps = 37/259 (14%)
Query 94 IASLNIQLTCNILTFGQLEQNVYG-ITIISGLPPEKPKNLSCIV-NEGKKMRCEWDGGRE 151
+ ++ + T + L F L+ ++ G + ++ +PPE+PK LSC N CEW
Sbjct 79 LRAVQVNDTGHYLCF--LDDHLVGTVPLLVDVPPEEPK-LSCFRKNPLVNAFCEWHPSST 135
Query 152 THLETNFTLKSEWATHKFADCKAKRDTPTSC--------------TVDYSTVYFVNIEVW 197
T + ++ K K D C ++ VY + V
Sbjct 136 PSPTTKAVMFAK----KINTTNGKSDFQVPCQYSQQLKSFSCEVEILEGDKVYHI---VS 188
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI--KSVIIL 255
+ N++G +S ++ F + V+P+PP NL V LK++W +P S +L
Sbjct 189 LCVANSVGSRSSHNVVFQSLKMVQPDPPANLVVSAIPGXPRWLKVSWQDPESWDPSYYLL 248
Query 256 KYNIQYR---TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
++ ++YR +K + W P A + + D ++V ++R +E G WS
Sbjct 249 QFELRYRPVWSKXFTVW----PLQVAQHQC--VIHDALRGVKHVVQVRGKEEFDIGQWSK 302
Query 313 WSEEASGITYEDRPSKAPS 331
WS E +G + P P+
Sbjct 303 WSPEVTGTPWLAEPRTTPA 321
>sp|Q62845|CNTN4_RAT Contactin-4 OS=Rattus norvegicus OX=10116
GN=Cntn4 PE=1 SV=1
Length=1026
Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 95/467 (20%), Positives = 172/467 (37%), Gaps = 70/467 (15%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP- 273
D + + P PP +++ E + +L+W I Y IQ RT + W +
Sbjct 590 DLIVRGPPGPPEAVTI--DEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVST 647
Query 274 -PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF 332
PE + TV L P+ EY FR G G S SE+ T E P P+
Sbjct 648 VPELVDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRR--TEEALPEVTPA- 704
Query 333 WYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT------ 385
+ S G ++ + + W+T+P NG+ Y V + TV A+
Sbjct 705 ----NVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPHGKMIWMLTVLASADASRY 760
Query 386 -------------KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA 432
++ V + N++ + LV ++ PA F + D++
Sbjct 761 VFRNESVRPFSPFEVKVGVFNNKGEGPFSPTTLVYSAEEEPTKPPASIFARSLSATDIEV 820
Query 433 FPKDNMLWVEWTTP----RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG---- 484
F W +P R ++ Y +++ W+ +D + +R
Sbjct 821 F---------WASPIGKNRGRIQGYEVKY------------WRHDDKEENARKIRTVGNQ 859
Query 485 ------NLAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVL 537
NL + Y ++V + G G S ++ ++ PPS+ P ++ +L
Sbjct 860 TSTKITNLKGNALYHLSVKAYNSAGTGPSSAAVNVTTRKPPPSQPPGNIIWNSSDSKIIL 919
Query 538 EWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
WDQ+ ++ Y + YR + T+V ++++ T L SL D Y++ + ++D
Sbjct 920 NWDQVKALDNESEVKGYKVLYRWNRQSSTSV-IETNKTSVEL-SLPFDEDYIIEIKPFSD 977
Query 598 EGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
GG PK + A L+ + ++ R
Sbjct 978 -GGDGSSSEQIRIPKISNSYARGSGASTSNACTLSAISTIMISLTAR 1023
>sp|Q8WZ42|TITIN_HUMAN Titin OS=Homo sapiens OX=9606 GN=TTN PE=1
SV=4
Length=34350
Score = 56.2 bits (134), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 116/441 (26%), Positives = 169/441 (38%), Gaps = 36/441 (8%)
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS-SILKLTWTNPSIKSVI 253
E V AENA G + I+ + NPP +V+ + S + + L W+ P +
Sbjct 29151 EFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGM 29210
Query 254 -ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
I+ Y I+ D W ++ E TR +TV DL+ EY FR+ + GKG D
Sbjct 29211 EIIGYIIEMCKADLGDWHKVNAEACVKTR--YTVTDLQAGEEYKFRVSAINGAGKG---D 29265
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT-----VQLVWKTLPPFEANGKILDYE 367
E I DR + AP + T R + + ++ P A D
Sbjct 29266 SCEVTGTIKAVDRLT-APELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSN 29324
Query 368 VTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
++L R H + T N ND TLTV N G S + T+ D
Sbjct 29325 LSL-RADIHTTDSFSTLTVENCN-RNDAGKYTLTVENNSG-SKSITFTVKVLDTPGPPGP 29381
Query 428 MDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN-L 486
+ K + + + W P I + V +A WQ R + N L
Sbjct 29382 ITFKDVTRGSATLM-WDAPLLDGGARIHHYVVEKREA-SRRSWQVISEKCTRQIFKVNDL 29439
Query 487 AESKCYLITVTPVYADGPGS----PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
AE Y V+ V G G PE I A + APP + V T K+ AVL W L
Sbjct 29440 AEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDT---SKSSAVLAW--L 29494
Query 543 PVDVQNG-FIRNYTIFYRTIIGNETAVNVDSSHTE---YTLSSLTSDTLYMVRMAAYTDE 598
D G I Y + R + V++ HT+ +T+ L T Y R+ A D
Sbjct 29495 KPDHDGGSRITGYLLEMRQ---KGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 29551
Query 599 GGKDGPEFTFTTPKFAQGEIE 619
G + P F++ + +IE
Sbjct 29552 GYSE-PREAFSSVIIKEPQIE 29571
Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 69/243 (28%), Positives = 92/243 (38%), Gaps = 55/243 (23%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNIQYRTKDASTWSQIPPEDTAST 280
P PP N+++ + + LTW P I Y I+ R K + W DTA T
Sbjct 14118 PGPPLNVTITDVNRFG--VSLTWEPPEYDGGAEITNYVIELRDKTSIRW------DTAMT 14169
Query 281 RS----SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
S TV D+ EY FR+R G G +PS A F
Sbjct 14170 VRAEDLSATVTDVVEGQEYSFRVRAQNRIGVG----------------KPSAATPFVKVA 14213
Query 337 DP-----------SHTQGYRTVQLVWKTLPPFEANGK-ILDYEVTLTRWKSHLQNYTVNA 384
DP S Q +VQL W+ PP + G IL Y + R + N+
Sbjct 14214 DPIERPSPPVNLTSSDQTQSSVQLKWE--PPLKDGGSPILGY--IIERCEEGKDNWIRCN 14269
Query 385 TKLTVNLT--------NDRYLATLTVRNLVGKSDAAVLTIP-ACDFQATHPVMDLKAFPK 435
KL LT ++YL ++ N G SD + + P D P MDL AF K
Sbjct 14270 MKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF-K 14328
Query 436 DNM 438
D +
Sbjct 14329 DGL 14331
Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 134/572 (23%), Positives = 216/572 (38%), Gaps = 67/572 (12%)
Query 70 NHFTIPKEQYTIINRTASSVTFTDIASLNIQLT----CNILTFGQLEQNVYGIT--IISG 123
+H+ I K + + ++ T S T++ +LN ++T N F + N YGI + SG
Sbjct 25762 SHYIIEKRETSRLSWTQVS---TEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESG 25818
Query 124 --------LPPEKPKNLSCIVNEGKKMRCEW-----DGGRETHLETNFTLKSEWATHKFA 170
PP P M W DGG T +E K + ++
Sbjct 25819 PVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGG--TEIEGYILEKRDKEGVRWT 25876
Query 171 DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENA--LGKVTSDHINF---DPVYKVKPNPP 225
C K T V T + E V AENA +G+ + + + D +Y P PP
Sbjct 25877 KCNKKTLTDLRLRVTGLTEGH-SYEFRVAAENAAGVGEPSEPSVFYRACDALYP--PGPP 25933
Query 226 HNLSVINSEELSSILKLTWTNPSIKSVIILK-YNIQYRTKDASTWSQIPPEDTASTRSSF 284
N V ++ S + L W+ P +K Y ++ + A W+ P T F
Sbjct 25934 SNPKVTDTSRSS--VSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTP-PTGLQGKQF 25990
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGY 344
TV LK TEY FRI + +G G + + + ++R + P D
Sbjct 25991 TVTKLKENTEYNFRICAINSEGVG---EPATLPGSVVAQER-IEPPEIELDADLRKVVVL 26046
Query 345 R---TVQL--VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT 399
R T++L K P E + + +T ++T+ + RY
Sbjct 26047 RASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRY--N 26104
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP----RESVKKYIL 455
LT+ N G S A + + D + + ++ KD++ + W P + YI+
Sbjct 26105 LTLENNSG-SKTAFVNVRVLDSPSAPVNLTIREVKKDSVT-LSWEPPLIDGGAKITNYIV 26162
Query 456 EWCVLSDKA-PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP----ESI 510
E + KA IT + T+ NL E Y V G G P E +
Sbjct 26163 EKRETTRKAYATIT-----NNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPV 26217
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
K PP + V V +N A ++W++ P I Y + +T + +
Sbjct 26218 KVSEPPLPPGR---VTLVDVTRNTATIKWEK-PESDGGSKITGYVVEMQTKGSEKWSTCT 26273
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
E T+S LT+ Y+ R+AA ++G D
Sbjct 26274 QVKTLEATISGLTAGEEYVFRVAAVNEKGRSD 26305
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 92/397 (23%), Positives = 154/397 (39%), Gaps = 37/397 (9%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNIQYRTKDASTWSQIPPEDTAST 280
P PP N++V + S+ + TW P I I+ Y +Q R + +WS + T +
Sbjct 20714 PGPPVNVTVKEISKDSAYV--TWEPPIIDGGSPIINYVVQKRDAERKSWSTV---TTECS 20768
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
++SF V +L+ Y FR+ E G G D E + P P K+
Sbjct 20769 KTSFRVANLEEGKSYFFRVFAENEYGIG---DPGETRDAVKASQTP--GPVVDLKV---R 20820
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTL----TRWKSHLQNYTV--NATKLTVNLTND 394
+ + + WK P + +I+ Y V +W+ +++ ++ +A LT
Sbjct 20821 SVSKSSCSIGWKK-PHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLT---EGK 20876
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE-----WTTPRES 449
Y ++ N G+ + +T+ A D P +DLK P L E P +
Sbjct 20877 EYTFRVSAENENGEGTPSEITVVARD-DVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 20935
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC--YLITVTPVYADGPGSP 507
+ W D T E V+ T + + +S Y IT+ V G+
Sbjct 20936 KPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTI 20995
Query 508 ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA 567
SIK K P+ GP ++ +V L+W P D I NY + R + N+
Sbjct 20996 -SIKVVGKPGIPT-GP-IKFDEVTAEAMTLKWAP-PKDDGGSEITNYILEKRDSVNNKWV 21051
Query 568 VNVDS-SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ T + ++ L Y R++A G +G
Sbjct 21052 TCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEG 21088
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 144/611 (24%), Positives = 224/611 (37%), Gaps = 94/611 (15%)
Query 77 EQYTIINRTASSVTFTDIASLNIQLT---------CNILTFGQLEQNVYGI--------- 118
+ Y + R S + +T++AS +Q+T N F + N YG+
Sbjct 22515 DHYIVQKRETSRLAWTNVAS-EVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPV 22573
Query 119 -TIISGLPPEKPKNLSCIVNEGKKMRCEW-----DGGRETHLETNFTL-KSEWATHKFAD 171
+ PP+ PKN M W DGG E N+ + + + A ++
Sbjct 22574 LAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEI---INYIVERRDKAGQRWIK 22630
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKV-----KPNPPH 226
C K T V T E + AENA G S P YK KP PP
Sbjct 22631 CNKKTLTDLRYKVSGLTEGH-EYEFRIMAENAAG--ISAPSPTSPFYKACDTVFKPGPPG 22687
Query 227 NLSVINSEELSSILKLTWTNPSIKS-VIILKYNIQYRTKDASTWSQI-PPEDTASTRSSF 284
N V+++ S + + W P I Y ++ + W + PP +T S+
Sbjct 22688 NPRVLDTSRSS--ISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKAT--SY 22743
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGY 344
T+ L EY RI M +G G + + EDR P D
Sbjct 22744 TITGLTENQEYKIRIYAMNSEGLG---EPALVPGTPKAEDR-MLPPEIELDADLRKVVTI 22799
Query 345 R---TVQLV--WKTLPPFEA-----NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN- 393
R T++L K P E +G+ LD K+ +++ T + T L V N
Sbjct 22800 RACCTLRLFVPIKGRPAPEVKWARDHGESLD--------KASIES-TSSYTLLIVGNVNR 22850
Query 394 -DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP----RE 448
D LTV N G S +A + + D + +K K ++ + W P
Sbjct 22851 FDSGKYILTVENSSG-SKSAFVNVRVLDTPGPPQDLKVKEVTKTSVT-LTWDPPLLDGGS 22908
Query 449 SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC-YLITVTPVYADGPGSP 507
+K YI+E + KA + H+T + + + C Y V G G P
Sbjct 22909 KIKNYIVEKRESTRKA-----YSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLP 22963
Query 508 ----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
ES+KA + PP K + V +N L W++ P I Y + +T
Sbjct 22964 AETAESVKASERPLPPGK---ITLMDVTRNSVSLSWEK-PEHDGGSRILGYIVEMQTKGS 23019
Query 564 NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
++ A TE T++ L Y R++A ++G D + + P A+ +V+
Sbjct 23020 DKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSV--PVIAKD----LVI 23073
Query 624 PVCLAFLLTTL 634
P L T
Sbjct 23074 PPAFKLLFNTF 23084
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 103/428 (24%), Positives = 168/428 (39%), Gaps = 52/428 (12%)
Query 198 VEAENALGKVT-SDHINF----DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS- 251
V A NA G S+ NF +P Y P PP V+++ + S + L WT P
Sbjct 30242 VTAVNAAGNSEPSEASNFISCREPSYT--PGPPSAPRVVDTTKHS--ISLAWTKPMYDGG 30297
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSS-FTVQDLKPFTEYVFRIRCMKEDGKGYW 310
I+ Y ++ + KD W ++ A+ R++ FTV DLK +Y FR+ + G
Sbjct 30298 TDIVGYVLEMQEKDTDQWYRV--HTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKG---M 30352
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT-------VQLVWKTLPPFEANGKI 363
S++SE + I +R + P D T R V + + P + +
Sbjct 30353 SEYSESIAEIEPVER-IEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQG 30411
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLA---TLTVRNLVGKSDAAVLTIPACD 420
+D + + T + + L V+ N RY A T+ N GK A VL + D
Sbjct 30412 IDLA------SRAIIDTTESYSLLIVDKVN-RYDAGKYTIEAENQSGKKSATVL-VKVYD 30463
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPR----ESVKKYILEWCVLSDKAPCITDWQQEDGT 476
P + +K +D++ + W P V YI+E + + ++
Sbjct 30464 TPGPCPSVKVKEVSRDSVT-ITWEIPTIDGGAPVNNYIVE-----KREAAMRAFKTVTTK 30517
Query 477 VHRTYLR-GNLAESKCYLITVTPVYADGPGSP-ESIKAYLKQAPPSKGPTVRTKKVGKNE 534
+T R L E Y V P G G P E+ A L P + V K+
Sbjct 30518 CSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKST 30577
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYTLSSLTSDTLYMVR 591
L W++ P+ + Y + G E V + + E+T++SL Y+ R
Sbjct 30578 VTLAWEK-PLYDGGSRLTGY-VLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFR 30635
Query 592 MAAYTDEG 599
+ A ++G
Sbjct 30636 IRAQNEKG 30643
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 92/404 (23%), Positives = 151/404 (37%), Gaps = 50/404 (12%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK-YNIQYRTKDASTWSQIPPEDTAST 280
P PP NL+V + S+ L W P I +K Y I R ++ + + +
Sbjct 25043 PGPPQNLAVKEVRKDSAFL--VWEPPIIDGGAKVKNYVIDKRESTRKAYANV---SSKCS 25097
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
++SF V++L Y FR+ E G G E P P D S
Sbjct 25098 KTSFKVENLTEGAIYYFRVMAENEFGVGV----PVETVDAVKAAEPPSPPGKVTLTDVSQ 25153
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLT-----RWKSHLQNYTVNATKLTVNLTNDR 395
T + L+W+ P + ++L Y V + +W ++ NA +T +
Sbjct 25154 T----SASLMWEK-PEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAV-VTGLSSGQE 25207
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL 455
Y + N GKSD VL +P DL P + + ++ ++ + +
Sbjct 25208 YQFRVKAYNEKGKSDPRVLGVPVI-------AKDLTIQPSLKLPFNTYSI--QAGEDLKI 25258
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI--------------TVTPVYA 501
E V+ P I+ W + DG + R N+ E+ + TVT +
Sbjct 25259 EIPVIGRPRPNIS-WVK-DGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNS 25316
Query 502 DGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR-T 560
G + L++ P GP VR +V + V+ W+ P I NY + R T
Sbjct 25317 AGTATENLSVIVLEKPGPPVGP-VRFDEVSADFVVISWEP-PAYTGGCQISNYIVEKRDT 25374
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
V+ + T ++ L + T Y R+ A + GK P
Sbjct 25375 TTTTWHMVSATVARTTIKITKLKTGTEYQFRIFA-ENRYGKSAP 25417
Score = 44.7 bits (104), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 100/412 (24%), Positives = 145/412 (35%), Gaps = 59/412 (14%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK-YNIQYRTKDASTWSQIPPEDTAST 280
P PP +L V S+ +L+W P +K Y I+ RT D W+++ P D ST
Sbjct 16839 PGPPKDLKV--SDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNP-DCGST 16895
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
+F V DL +Y FR+R G G + + + P + +
Sbjct 16896 --TFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKN 16953
Query 341 TQGYRTVQLVWKTLPPFEANGK-ILDYEVTLTRWK---------SHLQNYTVNATKLTVN 390
TV L WK PP G + Y V W V + TV
Sbjct 16954 -----TVHLSWK--PPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVE 17006
Query 391 --LTNDRYLATLTVRNLVGKSDAAVLTIPA-CDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
+ Y + N G S + P Q P +DLK F + VE T
Sbjct 17007 DLVEGGEYEFRVKAVNAAGVSKPSATVGPVTVKDQTCPPSIDLKEF-----MEVEEGTNV 17061
Query 448 ESVKKY------ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI------- 494
V K L W K P ++ ++ T++ + + C L+
Sbjct 17062 NIVAKIKGVPFPTLTWFKAPPKKP-----DNKEPVLYDTHVNKLVVDDTCTLVIPQSRRS 17116
Query 495 -----TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
T+T V G S E L + P GP ++ + V ++ L W P D
Sbjct 17117 DTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGP-IKFESVSADQMTLSWFP-PKDDGGS 17174
Query 550 FIRNYTIFYRTIIGNETAVNVDSSHTE--YTLSSLTSDTLYMVRMAAYTDEG 599
I NY I R +T V+V S E YT+ L Y+ R+ A G
Sbjct 17175 KITNYVIEKRE-ANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYG 17225
Score = 43.1 bits (100), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 101/440 (23%), Positives = 159/440 (36%), Gaps = 56/440 (13%)
Query 195 EVWVEAENALG----KVTSDHINF-DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
E V AENA G TS I DPV+ P+PP +++S + + + + W P
Sbjct 26981 EYRVYAENAAGLSLPSETSPLIRAEDPVFL--PSPPSKPKIVDSGK--TTITIAWVKPLF 27036
Query 250 KS-VIILKYNIQYRTKDASTWSQIPPEDTASTRSS-FTVQDLKPFTEYVFRIRCMKEDGK 307
I Y ++Y+ D + W S R + +T+ L EYVFR++ + + G
Sbjct 27037 DGGAPITGYTVEYKKSDDTDWKT----SIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGA 27092
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
SD S+ E+ P + ID + L+ K F
Sbjct 27093 SDPSDSSDPQIAKEREEEP------LFDIDSEMRK-----TLIVKAGASFTMTVPFRGRP 27141
Query 368 VTLTRWKSHLQNYTVNA--------TKLTVNLT--NDRYLATLTVRNLVGKSDAAVLTIP 417
V W + A T LT+ ND TLT++N++ + + L +
Sbjct 27142 VPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAA-SLTLVVK 27200
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRES----VKKYILEWCVLSDKAPCITDWQQE 473
D + ++ K++ + + W P VK Y +E S KA W
Sbjct 27201 VLDTPGPPTNITVQDVTKESAV-LSWDVPENDGGAPVKNYHIEKREASKKA-----WVSV 27254
Query 474 DGTVHR-TYLRGNLAESKCYLITVTPVYADGPGSP----ESIKAYLKQAPPSKGPTVRTK 528
+R +Y NL E Y V+ G G P E +K K +PP K +
Sbjct 27255 TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEK---LGVT 27311
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLY 588
+ K+ L W + D + + N V S T + +S L ++ Y
Sbjct 27312 SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKS-THHVVSGLRENSEY 27370
Query 589 MVRMAAYTDEGGKDGPEFTF 608
R+ A G D E
Sbjct 27371 FFRVFAENQAGLSDPRELLL 27390
Score = 42.4 bits (98), Expect = 0.025, Method: Compositional matrix adjust.
Identities = 73/325 (22%), Positives = 125/325 (38%), Gaps = 47/325 (14%)
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ Y ++ R D TWS + PE ++SF V +L P EY FR+ + E G G +D
Sbjct 19657 VTHYIVEKREADRKTWSTVTPE---VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDV 19713
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT---- 369
+ P P K++ + + L W LPP G +D +T
Sbjct 19714 PKPV----LASDPLSEPDPPRKLEVTEMT-KNSATLAW--LPPLRDGGAKIDGYITSYRE 19766
Query 370 ----LTRWKSH--LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA 423
RW + +++ ++ T L +Y + RN VG +++P + +
Sbjct 19767 EEQPADRWTEYSVVKDLSLVVTGLK---EGKKYKFRVAARNAVG------VSLPR-EAEG 19816
Query 424 THPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
+ + PK +L E T + KK +E V P + ED V ++L
Sbjct 19817 VYEAKEQLLPPK--ILMPEQITIKAG-KKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 19873
Query 484 GNLAESKCYLI------------TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
+ A+S LI ++T + G + + IK + AP P +
Sbjct 19874 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDT-QKIKVVVMDAPGPPQPPFDISDID 19932
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTI 556
+ L W +P++ I NY +
Sbjct 19933 ADACSLSW-HIPLEDGGSNITNYIV 19956
Score = 42.0 bits (97), Expect = 0.039, Method: Compositional matrix adjust.
Identities = 48/185 (26%), Positives = 76/185 (41%), Gaps = 24/185 (13%)
Query 164 WATHKFAD-CKAKRDTP---TSCTVDYSTVYFVNIE------VWVEAENALGKVTSDHIN 213
W T+ + C+AK S + +T VN+ V A+N G SD +
Sbjct 31681 WITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFG--ISDPLE 31738
Query 214 FDPVYKVK-----PNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDAS 267
V +K P P ++ + S ++ W P S I Y ++ R K +
Sbjct 31739 VSSVVIIKSPFEKPGAPGKPTITAVTKDSCVV--AWKPPASDGGAKIRNYYLEKREKKQN 31796
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
W + E+ T F+V++L EY FR++C G+ WS+ SE + D P
Sbjct 31797 KWISVTTEEIRET--VFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPIT--PKSDVPI 31852
Query 328 KAPSF 332
+AP F
Sbjct 31853 QAPHF 31857
Score = 40.0 bits (92), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 43/163 (26%), Positives = 70/163 (43%), Gaps = 23/163 (14%)
Query 149 GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
G+E T+K++ + A + P S D + +Y + +E N LG T
Sbjct 15351 GKEVKASDRLTMKNDHIS-------AHLEVPKSVRAD-AGIYTITLE------NKLGSAT 15396
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNIQYRTKDAS 267
+ IN + P P ++ S+ S KLTW P IL Y ++ R
Sbjct 15397 AS-INVKVIGL--PGPCKDIKA--SDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRR 15451
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
T+ P + + S+TV+DL P EY FR++ + + G G +
Sbjct 15452 TYI---PVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY 15491
Score = 38.1 bits (87), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 53/220 (24%), Positives = 83/220 (38%), Gaps = 31/220 (14%)
Query 149 GRETHLETNFTLKSEWATH-----KFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA--- 200
RE H++ TL+ K K RD PT +D + V +E+ A
Sbjct 18152 AREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPV-GSKLEIRNAAHED 18210
Query 201 --------ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKS 251
EN G S ++ + KP PP +L V SE LTW P
Sbjct 18211 GGIYSLTVENPAG---SKTVSVKVLVLDKPGPPRDLEV--SEIRKDSCYLTWKEPLDDGG 18265
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+I Y ++ R ++ WS P S + S + L +Y+FR+ + G+G +
Sbjct 18266 SVITNYVVERRDVASAQWS---PLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFV 18322
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
+ + + P P + +D T+ V LVW
Sbjct 18323 ETPKPIKALD-PLHPPGPPKDLHHVDVDKTE----VSLVW 18357
Score = 38.1 bits (87), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 90/375 (24%), Positives = 140/375 (37%), Gaps = 41/375 (11%)
Query 241 KLTWTNPSIKS-VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
KLTW +P I Y I+ R D W+ P TR + TVQ L Y FRI
Sbjct 17561 KLTWFSPEDDGGSPITNYVIEKRESDRRAWT---PVTYTVTRQNATVQGLIQGKAYFFRI 17617
Query 300 RCMKEDGKGYWSDWSEE---ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
G G + + SE IT +RP TV L W P
Sbjct 17618 AAENSIGMGPFVETSEALVIREPITVPERPEDL--------EVKEVTKNTVTLTWNP-PK 17668
Query 357 FEANGKILDY----EVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSD 410
++ +I++Y + T + N + + K TV D Y ++ N+VG+
Sbjct 17669 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 17728
Query 411 AAVLTIP-ACDFQATHPVMDLKAFPKDNMLWVEW--------TTPRESVKKYILEWCVLS 461
+ T P C + P + L K + E P+ V + E VL
Sbjct 17729 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 17788
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
D T + T+ ++ ++S Y + V G + + + PP
Sbjct 17789 DDR---THIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQ-VNVVDRPGPPV- 17843
Query 522 GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT--L 579
GP V +V K+ V+ W + P+D I NY I + +G + + V S+ + T +
Sbjct 17844 GP-VSFDEVTKDYMVISW-KPPLDDGGSKITNY-IIEKKEVGKDVWMPVTSASAKTTCKV 17900
Query 580 SSLTSDTLYMVRMAA 594
S L Y+ R+ A
Sbjct 17901 SKLLEGKDYIFRIHA 17915
Score = 36.6 bits (83), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 27/117 (23%), Positives = 51/117 (44%), Gaps = 5/117 (4%)
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK-YNIQYRTKDASTW 269
+ DP++ P PP V ++ S + L W P+ +K Y ++ + + + W
Sbjct 16623 EVAGDPIFP--PGPPSCPEV--KDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDW 16678
Query 270 SQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
++ D T V +LK +Y FR++ + E G+ SD + E ++ P
Sbjct 16679 KRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEP 16735
Score = 36.2 bits (82), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 58/232 (25%), Positives = 92/232 (40%), Gaps = 34/232 (15%)
Query 147 DGGRETHLETNFTL-KSEWATHKFADC-KAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
DGG E TN+ L K + +K+ C A + T T + + + V AEN
Sbjct 21030 DGGSEI---TNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYT---FRVSAENKY 21083
Query 205 GKVTSDHINFDPVYKVKP------NPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKY 257
G + + +P+ P PP N+ + + +S LTWT+P I Y
Sbjct 21084 G--VGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVS----LTWTDPKKTGGSPITGY 21137
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
+++++ +++ W + T F V L EY FR+ + G G S SE
Sbjct 21138 HLEFKERNSLLWKRA--NKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPV 21195
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEV 368
+ D P K P R +V L+W T P ++ K+ Y V
Sbjct 21196 VALDPIDPPGK---------PEVINITRNSVTLIW-TEPKYDGGHKLTGYIV 21237
Score = 35.8 bits (81), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 84/414 (20%), Positives = 152/414 (37%), Gaps = 68/414 (16%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNIQYRTKDASTWSQIPPEDTAST 280
P PP + + +S + S + L W+ P + Y ++ R + W+ + + T
Sbjct 28094 PGPPAKIRIADSTKSS--ITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRT 28151
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
+ + V +LKP Y FR+ + G+G + +E + P +
Sbjct 28152 -TEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIA 28210
Query 341 TQGYRTVQLV-WKTLPPFEANGKILDYEVTLTRWKSHLQN------YTVNATKLTVNLT- 392
G L+ +K PP T+T W+ +N Y++ T + LT
Sbjct 28211 KAGEDVQVLIPFKGRPP-----------PTVT-WRKDEKNLGSDARYSIENTDSSSLLTI 28258
Query 393 -----NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD--NMLW----V 441
ND LT+ N VG+ ++ +++ D A + +K + +LW +
Sbjct 28259 PQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLI 28318
Query 442 EWTTPRESVKKYILE--------WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
+ +P + Y++E W V+S K ++ +L+E +
Sbjct 28319 DGGSP---IINYVIEKRDATKRTWSVVSHKCSST------------SFKLIDLSEKTPFF 28363
Query 494 ITVTPVYADGPGSP----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
V G G P E +KA AP + K K +L W + D G
Sbjct 28364 FRVLAENEIGIGEPCETTEPVKAAEVPAPIRD---LSMKDSTKTSVILSWTK--PDFDGG 28418
Query 550 FIRNYTIFYRTIIGNETAVNVDSSHT-EYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ + R G +T + S T E +S L ++ R+ A ++G D
Sbjct 28419 SVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD 28472
Score = 34.7 bits (78), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 109/496 (22%), Positives = 187/496 (38%), Gaps = 80/496 (16%)
Query 147 DGGRETHLETNFTL-KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
DGG E TN+ + K E + +A A TSC+V+ + + + AEN G
Sbjct 20342 DGGSEI---TNYIVDKRETSRPNWAQVSATVPI-TSCSVE-KLIEGHEYQFRICAENKYG 20396
Query 206 KVTSDHINFDPVYKVKP-NPPHNLSVINSEELSSILK----LTWTNPSIKS-VIILKYNI 259
D + +P P +PP + +S+I K ++W P+ I Y +
Sbjct 20397 --VGDPVFTEPAIAKNPYDPPGRC---DPPVISNITKDHMTVSWKPPADDGGSPITGYLL 20451
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ R A W+++ + L+ TEY FR+ + + G G SD S+ A
Sbjct 20452 EKRETQAVNWTKV--NRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYA 20509
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH--- 376
+ P P+F D + + +V L W P ++ I+ Y V + R S
Sbjct 20510 RDPQ-YPPGPPAFPKVYDTTRS----SVSLSWGK-PAYDGGSPIIGYLVEVKRADSDNWV 20563
Query 377 ----LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA 432
QN ++T + + +Y + N +G SD + D H
Sbjct 20564 RCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPS-------DVPDKH------- 20609
Query 433 FPKDNMLWVEWTTPRESVKKYILEWCV-------LSDKAPCITDWQQED----------- 474
+PKD ++ E + K IL V + + P W + +
Sbjct 20610 YPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDI 20669
Query 475 -GTVHRTYLRG---NLAESKCYLITVTPVYADGPGSPE---SIKAYLKQAPPSKGPTVRT 527
T T+LR N ++ Y++T+ + G E +K PP V
Sbjct 20670 KSTDFDTFLRCENVNKYDAGKYILTL----ENSCGKKEYTIVVKVLDTPGPPV---NVTV 20722
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSDT 586
K++ K+ A + W+ +D + I NY + R + V + S T + +++L
Sbjct 20723 KEISKDSAYVTWEPPIIDGGSPII-NYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGK 20781
Query 587 LYMVRMAAYTDEGGKD 602
Y R+ A + G D
Sbjct 20782 SYFFRVFAENEYGIGD 20797
Score = 34.3 bits (77), Expect = 8.9, Method: Compositional matrix adjust.
Identities = 69/274 (25%), Positives = 107/274 (39%), Gaps = 40/274 (15%)
Query 356 PFEANGKILDYEVTLTRWKSHLQ------NYTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
P E G +DY + R SHL + + K+T L + Y+ +T N G
Sbjct 26834 PQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVG 26893
Query 410 DA-AVLTIPACD-FQATHP--VMDLKAFPKDNMLWVEWTTPRE----SVKKYILE----- 456
+ + I A D F P +++ + K++M W+ P + YI+E
Sbjct 26894 EPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLC-WSRPESDGGSEISGYIIERREKN 26952
Query 457 ---WCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPGSPESIKA 512
W V +K P D V T LR G E + Y + SP I+A
Sbjct 26953 SLRW-VRVNKKPVY------DLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSP-LIRA 27004
Query 513 ---YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
+PPSK V + GK + W + P+ I YT+ Y+ + +
Sbjct 27005 EDPVFLPSPPSKPKIVDS---GKTTITIAWVK-PLFDGGAPITGYTVEYKKSDDTDWKTS 27060
Query 570 VDS-SHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ S TEYT+S LT+ Y+ R+ + G D
Sbjct 27061 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD 27094
>sp|Q0E9H9|DSCA1_DROME Cell adhesion molecule Dscam1 OS=Drosophila
melanogaster OX=7227 GN=Dscam1 PE=1 SV=1
Length=2016
Score = 55.8 bits (133), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 53/169 (31%), Positives = 82/169 (49%), Gaps = 13/169 (8%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A NA G SD + + + + P P+ L V++ S ++L+W P + + +Y I
Sbjct 892 ATNAFG---SDDASINMIVQEVPEMPYALKVLDKSGRS--VQLSWAQPYDGNSPLDRYII 946
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+++ AS WS+I + VQ L P T Y IR + E+ G S SE +
Sbjct 947 EFKRSRAS-WSEIDRVIVPGHTTEAQVQKLSPATTY--NIRIVAENAIGT-SQSSEAVTI 1002
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
IT E+ PS P K++P + T+++ WK P E NG+IL Y V
Sbjct 1003 ITAEEAPSGKPQN-IKVEPVNQT---TMRVTWKPPPRTEWNGEILGYYV 1047
Score = 38.9 bits (89), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 74/326 (23%), Positives = 131/326 (40%), Gaps = 38/326 (12%)
Query 65 IVWKTNHFTI-PKE--QYTIINRTASSVTFTDIASLNIQLT--CNILTFGQLEQNVYG-- 117
I+W N+ + PK +YTI S+ ++SL+I+ T + F + N +G
Sbjct 843 ILWNMNNMRLDPKNDNRYTIREEILSTGV---MSSLSIKRTERSDSALFTCVATNAFGSD 899
Query 118 ---ITIISGLPPEKPKNLSCIVNEGKKMRCEW----DGGR--ETHLETNFTLKSEWATHK 168
I +I PE P L + G+ ++ W DG + ++ ++ W+
Sbjct 900 DASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEID 959
Query 169 FADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHN 227
+ +T Y + I AENA+G +S+ + + P N
Sbjct 960 RVIVPGHTTEAQVQKLSPATTYNIRIV----AENAIGTSQSSEAVTIITAEEAPSGKPQN 1015
Query 228 LSVINSEELSSILKLTWTNPSIK--SVIILKYNIQYR---TKDASTWSQIPPEDTASTRS 282
+ V + + +++TW P + IL Y + Y+ T + + I
Sbjct 1016 IKVEPVNQ--TTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEH 1073
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
+ +Q+L+ +T+Y I+ + G G SEE T E PS+ PS T
Sbjct 1074 NLELQNLRVYTQYSVVIQAFNKIGAG---PLSEEEKQFTAEGTPSQPPS----DTACTTL 1126
Query 343 GYRTVQLVWKTLPPFEANGKILDYEV 368
+T+++ W + P ANG I Y+V
Sbjct 1127 TSQTIRVGWVSPPLESANGVIKTYKV 1152
>sp|Q62682|CNTN3_RAT Contactin-3 OS=Rattus norvegicus OX=10116
GN=Cntn3 PE=1 SV=1
Length=1028
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 99/406 (24%), Positives = 159/406 (39%), Gaps = 34/406 (8%)
Query 217 VYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP--P 274
+ + P PP N+ V E + +L+WT + ++ Y +Q RT + W + P
Sbjct 593 IVRGSPGPPENVKV--DEITDTTAQLSWTEGTDSHSPVISYAVQARTPFSVGWQNVRTVP 650
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
E + TV +L P+ EY FR+ + G G S SE+ T E P APS
Sbjct 651 EAIDGKTRTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVR--TEEAAPEVAPS--- 705
Query 335 KIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVT-----LTRWKSHLQNYTVNATKLT 388
+ S G R+ + + W +P NG Y V +T W + N +
Sbjct 706 --EVSGGGGSRSELVITWDPVPEELQNGGGFGYVVAFRPLGVTTWIQTVVTSPDNPRYVF 763
Query 389 VN---LTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEW 443
N + Y + V N G+ + V T+ + + + T + A + + V W
Sbjct 764 RNESIVPFSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSHISAHSLSSSEIEVSW 823
Query 444 TT-PRESVKKYILEWCVL---SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPV 499
T P +S +L + V + + + G LRG L + Y V
Sbjct 824 NTIPWKSSNGRLLGYEVRYWNNGGEEESSSKVKVAGNQTSAVLRG-LKSNLAYYTAVRAY 882
Query 500 YADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
G G ++ A K+ PPS+ P + +L W+Q+ + Y +FY
Sbjct 883 NTAGAGPFSATVNATTKKTPPSQPPGNVVWNATDTKVLLNWEQVKALENESEVTGYKVFY 942
Query 559 RTIIGNETAV-NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
RT N V N + + E L + D Y++ + A TD G DG
Sbjct 943 RTSSQNNVQVLNTNKTSAELLL-PIKED--YIIEVKATTD--GGDG 983
Score = 34.3 bits (77), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 36/130 (28%), Positives = 61/130 (47%), Gaps = 13/130 (10%)
Query 503 GPGSPE--SIKAYLKQAPPSKGPTVRTKKVG-KNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
G G P S K ++A P P+ + G ++E V+ WD +P ++QNG Y + +R
Sbjct 682 GGGEPSLPSEKVRTEEAAPEVAPSEVSGGGGSRSELVITWDPVPEELQNGGGFGYVVAFR 741
Query 560 TIIGNETAVNV-----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFA 614
+G T + D+ + S+ + Y V++ Y ++G +GP F+ T F+
Sbjct 742 P-LGVTTWIQTVVTSPDNPRYVFRNESIVPFSPYEVKVGVYNNKG--EGP-FSPVTTVFS 797
Query 615 QGEIEAIVVP 624
E E V P
Sbjct 798 AEE-EPTVAP 806
>sp|Q69Z26|CNTN4_MOUSE Contactin-4 OS=Mus musculus OX=10090 GN=Cntn4
PE=1 SV=2
Length=1026
Score = 55.5 bits (132), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 95/467 (20%), Positives = 172/467 (37%), Gaps = 70/467 (15%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP- 273
D + + P PP +++ E + +L+W I Y IQ RT + W +
Sbjct 590 DLIVRGPPGPPEAVTI--DEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVNT 647
Query 274 -PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF 332
P+ + TV L P+ EY FR G G S SE+ T E P P+
Sbjct 648 VPDLVDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRR--TEEALPEVTPA- 704
Query 333 WYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT------ 385
+ S G ++ + + W+T+P NG+ Y V + TV A+
Sbjct 705 ----NVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPHGKMIWMLTVLASADASRY 760
Query 386 -------------KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA 432
++ V + N++ + LV ++ PA F + D++
Sbjct 761 VFRNESVRPFSPFEVKVGVFNNKGEGPFSPTTLVYSAEEEPTKPPASIFARSLSATDIEV 820
Query 433 FPKDNMLWVEWTTP----RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG---- 484
F W +P R ++ Y +++ W+ +D + +R
Sbjct 821 F---------WASPIGKNRGRIQGYEVKY------------WRHDDKEENAKKIRTVGNQ 859
Query 485 ------NLAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVL 537
NL S Y ++V + G G S ++ ++ PPS+ P ++ +L
Sbjct 860 TSTKITNLKGSALYHLSVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIIL 919
Query 538 EWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
WDQ+ ++ Y + YR + T+V ++++ T L SL D Y++ + ++D
Sbjct 920 NWDQVKALDNESEVKGYKVLYRWNRQSSTSV-IETNKTSVEL-SLPFDEDYIIEIKPFSD 977
Query 598 EGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
GG PK + A L+ + ++ R
Sbjct 978 -GGDGSSSEQIRIPKISNSYARGSGASTSNACTLSAISTIMISLTAR 1023
>sp|P70225|I11RB_MOUSE Interleukin-11 receptor subunit alpha-2
OS=Mus musculus OX=10090 GN=Il11ra2 PE=2 SV=4
Length=432
Score = 54.7 bits (130), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 51/218 (23%), Positives = 86/218 (39%), Gaps = 25/218 (11%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD 177
+T+ G PP +P+ +SC + + C W G+ + L T + + + +++R+
Sbjct 105 VTLKLGFPPARPE-VSCQAVDYENFSCTWSPGQVSGLPTRYL--TSYRKKTLPGAESQRE 161
Query 178 TPTS----CTVD---YSTVYFVNIEVWVEAE------NALGKVTSDHINFDPVYKVKPNP 224
+P++ C D S E W E N LG T ++ ++P+P
Sbjct 162 SPSTGPWPCPQDPLEASRCVVHGAEFWSEYRINVTEVNPLGASTC-LLDVRLQSILRPDP 220
Query 225 PHNLSVINSEELSSILKLTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P L V + L +WT P+ + +LK+ +QYR WS + P
Sbjct 221 PQGLRVESVPGYPRRLHASWTYPASWRRQPHFLLKFRLQYRPAQHPAWSTVEPIGLEE-- 278
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ D + R+ G WS WS EA G
Sbjct 279 ---VITDTVAGLPHAVRVSARDFLDAGTWSAWSPEAWG 313
>sp|Q64385|I11RA_MOUSE Interleukin-11 receptor subunit alpha-1
OS=Mus musculus OX=10090 GN=Il11ra1 PE=1 SV=1
Length=432
Score = 54.7 bits (130), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 51/218 (23%), Positives = 86/218 (39%), Gaps = 25/218 (11%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD 177
+T+ G PP +P+ +SC + + C W G+ + L T + + + +++R+
Sbjct 105 VTLKLGFPPARPE-VSCQAVDYENFSCTWSPGQVSGLPTRYL--TSYRKKTLPGAESQRE 161
Query 178 TPTS----CTVD---YSTVYFVNIEVWVEAE------NALGKVTSDHINFDPVYKVKPNP 224
+P++ C D S E W E N LG T ++ ++P+P
Sbjct 162 SPSTGPWPCPQDPLEASRCVVHGAEFWSEYRINVTEVNPLGASTC-LLDVRLQSILRPDP 220
Query 225 PHNLSVINSEELSSILKLTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P L V + L +WT P+ + +LK+ +QYR WS + P
Sbjct 221 PQGLRVESVPGYPRRLHASWTYPASWRRQPHFLLKFRLQYRPAQHPAWSTVEPIGLEE-- 278
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ D + R+ G WS WS EA G
Sbjct 279 ---VITDAVAGLPHAVRVSARDFLDAGTWSAWSPEAWG 313
>sp|Q64605|PTPRS_RAT Receptor-type tyrosine-protein phosphatase
S OS=Rattus norvegicus OX=10116 GN=Ptprs PE=1 SV=2
Length=1907
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 55/164 (34%), Positives = 82/164 (50%), Gaps = 17/164 (10%)
Query 448 ESVKKYILEWCVLSDKAPCITDWQ-QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ V Y++E+ S P +Q +ED T R Y G L+ + Y I V+ V + G G
Sbjct 345 DPVSYYVIEYKSKSQDGP----YQIKEDITTTR-YSIGGLSPNSEYEIWVSAVNSIGQGP 399
Query 507 P-ESIKAYL-KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT---- 560
P ES+ +QAP S V+ + + +++W++ PV+ NG IR Y ++Y
Sbjct 400 PSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEE-PVE-PNGLIRGYRVYYTMEPEH 457
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
+GN NVD S T+ SL D Y VR+ A+T G DGP
Sbjct 458 PVGNWQKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVG--DGP 498
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 46/148 (31%), Positives = 64/148 (43%), Gaps = 17/148 (11%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P P NL E S + L+W+ P +SVI KY + +R D T
Sbjct 512 PGQPMNLRAEAKSETS--IGLSWSAPRQESVI--KYELLFREGDRGREVG----RTFDPT 563
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
++F V+DLKP TEY FR+ G G ++ + T + +PS P D T
Sbjct 564 TAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQR---TLQAKPSAPPQ-----DVKCT 615
Query 342 QGYRTVQLV-WKTLPPFEANGKILDYEV 368
T LV W+ PP NG ++ Y V
Sbjct 616 SLRSTAILVSWRPPPPETHNGALVGYSV 643
Score = 50.4 bits (119), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 109/410 (27%), Positives = 168/410 (41%), Gaps = 54/410 (13%)
Query 220 VKPNPPHNLSVINSEELSSILKLTW--TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
VK P + + +E ++ + +TW NP S Y I+Y++K QI ED
Sbjct 315 VKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSY----YVIEYKSKSQDGPYQIK-EDI 369
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
+TR +++ L P +EY + + G+G SE T E P+ AP
Sbjct 370 TTTR--YSIGGLSPNSEYEIWVSAVNSIGQG---PPSESVVTRTGEQAPASAPRNVQARM 424
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH----LQNYTVNATKLTV--NL 391
S T T+ + W+ P E NG I Y V T H Q + V+ + LT +L
Sbjct 425 LSAT----TMIVQWEE--PVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSL 478
Query 392 TNDRYLATLTVRNLVGKS--DAAVLTIPACDFQATHP--VMDLKAFPK-DNMLWVEWTTP 446
D T TVR L S D + Q P M+L+A K + + + W+ P
Sbjct 479 LEDE---TYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAP 535
Query 447 R-ESVKKYILEWCVLSDKAPCITDWQQEDGTVH---RTYLRGNLAESKCYLITVTPVYAD 502
R ESV KY L + D +E G ++ +L + Y +
Sbjct 536 RQESVIKYELLFRE--------GDRGREVGRTFDPTTAFVVEDLKPNTEYAFRLAARSPQ 587
Query 503 GPGSPESI-KAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G G+ ++ + QA PS P V+ + ++ W P + NG + Y++ YR
Sbjct 588 GLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRP 647
Query 561 IIGNE-----TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+G+E N+ + T+ L +L T Y V AYT+ G GPE
Sbjct 648 -LGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVG--PGPE 694
Score = 39.3 bits (90), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 82/420 (20%), Positives = 159/420 (38%), Gaps = 67/420 (16%)
Query 219 KVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT-----KDASTWSQI 272
+ KP+ PP ++ + + ++ P + ++ Y+++YR D + I
Sbjct 602 QAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNI 661
Query 273 PPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI---TYEDRPSKA 329
PP T + ++ L+ +TEY E G G E+S + T ED PS
Sbjct 662 PP-----TTTQILLEALEKWTEYRVTAVAYTEVGPG------PESSPVVVRTDEDVPSAP 710
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS-------HLQNYTV 382
P K++ + ++++W++ P +G+I Y+V R + +++ +
Sbjct 711 PR---KVE-AEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIML 766
Query 383 -NATKLTVNLTNDRYLATLTVRNLVGKSDAA------VLTIPACDFQATHPVMDLKAFPK 435
+A ++ + ++TV K D A V+T A P + ++ P+
Sbjct 767 ADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAV---LGRPTLSVQQTPE 823
Query 436 DNMLWVEWTTPRESVKKYILEWCV---LSDKAPC---ITDWQQEDGTVHRTYLRGNLAES 489
++L W P ++ + +L + + D AP + W++ +
Sbjct 824 GSLL-ARWEPPADAAEDPVLGYRLQFGREDAAPATLELAAWERR--------FAAPAHKG 874
Query 490 KCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV--RTKKVGKNEAVLEW-DQLPVDV 546
Y+ + G G S + + P P + V +L W +P +
Sbjct 875 ATYVFRLAARGRAGLGEEASAALSIPEDAPRGFPQILGAAGNVSAGSVILRWLPPVPAE- 933
Query 547 QNGFIRNYTIFYR-------TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+NG I YT+ R A + T TL L +T Y +R+ A+T G
Sbjct 934 RNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLQGLRPETAYELRVRAHTRRG 993
>sp|B0V2N1|PTPRS_MOUSE Receptor-type tyrosine-protein phosphatase
S OS=Mus musculus OX=10090 GN=Ptprs PE=1 SV=1
Length=1907
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 55/164 (34%), Positives = 82/164 (50%), Gaps = 17/164 (10%)
Query 448 ESVKKYILEWCVLSDKAPCITDWQ-QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ V Y++E+ S P +Q +ED T R Y G L+ + Y I V+ V + G G
Sbjct 345 DPVSYYVIEYKSKSQDGP----YQIKEDITTTR-YSIGGLSPNSEYEIWVSAVNSIGQGP 399
Query 507 P-ESIKAYL-KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT---- 560
P ES+ +QAP S V+ + + +++W++ PV+ NG IR Y ++Y
Sbjct 400 PSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEE-PVE-PNGLIRGYRVYYTMEPEH 457
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
+GN NVD S T+ SL D Y VR+ A+T G DGP
Sbjct 458 PVGNWQKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVG--DGP 498
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 46/148 (31%), Positives = 64/148 (43%), Gaps = 17/148 (11%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P P NL E S + L+W+ P +SVI KY + +R D T
Sbjct 512 PGQPMNLRAEAKSETS--IGLSWSAPRQESVI--KYELLFREGDRGREVG----RTFDPT 563
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
++F V+DLKP TEY FR+ G G ++ + T + +PS P D T
Sbjct 564 TAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQR---TLQAKPSAPPQ-----DVKCT 615
Query 342 QGYRTVQLV-WKTLPPFEANGKILDYEV 368
T LV W+ PP NG ++ Y V
Sbjct 616 SLRSTAILVSWRPPPPETHNGALVGYSV 643
Score = 50.8 bits (120), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 109/410 (27%), Positives = 168/410 (41%), Gaps = 54/410 (13%)
Query 220 VKPNPPHNLSVINSEELSSILKLTW--TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
VK P + + +E ++ + +TW NP S Y I+Y++K QI ED
Sbjct 315 VKSLPKAPGTPVVTENTATSITVTWDSGNPDPVSY----YVIEYKSKSQDGPYQIK-EDI 369
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
+TR +++ L P +EY + + G+G SE T E P+ AP
Sbjct 370 TTTR--YSIGGLSPNSEYEIWVSAVNSIGQG---PPSESVVTRTGEQAPASAPRNVQARM 424
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH----LQNYTVNATKLTV--NL 391
S T T+ + W+ P E NG I Y V T H Q + V+ + LT +L
Sbjct 425 LSAT----TMIVQWEE--PVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSL 478
Query 392 TNDRYLATLTVRNLVGKS--DAAVLTIPACDFQATHP--VMDLKAFPK-DNMLWVEWTTP 446
D T TVR L S D + Q P M+L+A K + + + W+ P
Sbjct 479 LEDE---TYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSETSIGLSWSAP 535
Query 447 R-ESVKKYILEWCVLSDKAPCITDWQQEDGTVH---RTYLRGNLAESKCYLITVTPVYAD 502
R ESV KY L + D +E G ++ +L + Y +
Sbjct 536 RQESVIKYELLFRE--------GDRGREVGRTFDPTTAFVVEDLKPNTEYAFRLAARSPQ 587
Query 503 GPGSPESI-KAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G G+ ++ + QA PS P V+ + ++ W P + NG + Y++ YR
Sbjct 588 GLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRP 647
Query 561 IIGNE-----TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+G+E N+ + T+ L +L T Y V AYT+ G GPE
Sbjct 648 -LGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVG--PGPE 694
Score = 35.4 bits (80), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 85/427 (20%), Positives = 158/427 (37%), Gaps = 81/427 (19%)
Query 219 KVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT-----KDASTWSQI 272
+ KP+ PP ++ + + ++ P + ++ Y+++YR D + I
Sbjct 602 QAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNI 661
Query 273 PPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI---TYEDRPSKA 329
PP T + ++ L+ +TEY E G G E+S + T ED PS
Sbjct 662 PP-----TTTQILLEALEKWTEYRVTAVAYTEVGPG------PESSPVVVRTDEDVPSAP 710
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN--------YT 381
P K++ + ++++W++ P +G+I Y+V R +
Sbjct 711 PR---KVE-AEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIML 766
Query 382 VNATKLTVNLTNDRYLATLTVRNLVGKSDAA------VLTIPACDFQATHPVMDLKAFPK 435
+A ++ + ++TV K D A V+T A P + ++ P+
Sbjct 767 ADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAV---LGRPTLSVQQTPE 823
Query 436 DNMLWVEWTTPRESVKKYILEWCV---LSDKAPC---ITDWQQEDGT--------VHRTY 481
++L W P ++ + +L + + D AP + W++ V R
Sbjct 824 GSLL-ARWEPPADAAEDPVLGYRLQFGREDAAPATLELAAWERRFAAPAHKGATYVFRLA 882
Query 482 LRGNLAESKCYLITVTPVYADGP-GSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW- 539
RG + ++ + D P G P+ + A V +L W
Sbjct 883 ARGRAGLGEEAAAALS-IPEDAPRGFPQILGA--------------AGNVSAGSVLLRWL 927
Query 540 DQLPVDVQNGFIRNYTIFYR-------TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+P + +NG I YT+ R A + T TL L +T Y +R+
Sbjct 928 PPVPAE-RNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLRGLRPETAYELRV 986
Query 593 AAYTDEG 599
A+T G
Sbjct 987 RAHTRRG 993
>sp|Q8K3K1|USH2A_RAT Usherin OS=Rattus norvegicus OX=10116 GN=Ush2a
PE=1 SV=2
Length=5125
Score = 55.1 bits (131), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 94/395 (24%), Positives = 144/395 (36%), Gaps = 53/395 (13%)
Query 191 FVNIEVWVEA-ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
F E+ ++A + G H+ V PP L + S +++ WT P+
Sbjct 3825 FTQYEIRIQACQEGCGVSPGTHVRTLEAAPVGLMPPL-LKALGSH----CIEVKWTPPTR 3879
Query 250 KSVIILKYNIQYRTKDAS------TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
+ II Y I R D WS+ E T T + L+PFT Y +R+R
Sbjct 3880 PNGIITSYVIHRRPADTEEESLLFVWSEGALEFTDDTDT------LRPFTLYEYRVRAWN 3933
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
G S WS S T E P P+ W ++ +H+ V L W P NG I
Sbjct 3934 SKGV-VDSPWS---SVQTLEAPPQDLPAPWVQVTSAHS-----VLLNWTE--PEAPNGLI 3982
Query 364 LDYEVTLTR-------WKSHLQNYTVNATKLTVNLTN----DRYLATLTVRNLVGKSDAA 412
Y V S + +TV + +L Y + N GK +
Sbjct 3983 SQYHVIYQERPDEAAPGSSTVHAFTVKGSSRQAHLFGLEPFTTYHIGVAAVNRAGKVSSP 4042
Query 413 VLTIPACDFQATHPVMDLKAFPKDN--MLWVEWTTPRESVKKYILEWCVLSDKAPCITDW 470
I + A +M+ A ++ L ++W+ P + I + V SD P
Sbjct 4043 WTLIKTLE-SAPSGLMNFTAEQREGGRALLLQWSEPVRT-NGVIKAYNVFSDGLP----- 4095
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKV 530
E + R +L LA Y++T+ A G + ++APP + V
Sbjct 4096 --EYSGLGRQFLFRRLAPFTLYILTLEACTAAGCAHSVPQTLWTEEAPPDSQMAPTIQSV 4153
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE 565
L W Q P + NG I Y + R + G +
Sbjct 4154 EPTSVRLHWSQ-PAN-PNGKIIRYEVIRRRLQGED 4186
Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 51/180 (28%), Positives = 76/180 (42%), Gaps = 23/180 (13%)
Query 193 NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL-SVINSEELSSILKLTWTNPSIKS 251
N V V A N+ G V SD ++ + + P P L S + + L++ W+ P+ +
Sbjct 2395 NYTVQVNASNSQGSVLSDRVSVE----MPPGAPDGLLSPRLAAATPTSLQVVWSTPARNN 2450
Query 252 VI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
+Y +Q R D ST + S S+ V L+PFT Y FR+ G Y
Sbjct 2451 APGSPRYQLQMR-PDPSTRGLLELFPIPSALLSYEVTGLQPFTVYEFRLVATNGFGSAY- 2508
Query 311 SDWSEEASGITYEDRPS--KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
SDW+ +T ED+P AP K + + W+ P E NG I Y +
Sbjct 2509 SDWTPL---MTTEDKPGPMDAPVLNVKAG--------MMSVAWRK--PTECNGAITHYNI 2555
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 76/337 (23%), Positives = 123/337 (36%), Gaps = 40/337 (12%)
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
+R S L+PFTEY++R+ G SDWS G T P P+ PS
Sbjct 1900 SRQSVYESGLQPFTEYLYRVT-ASHKGGSVSSDWSR---GRTLGSAPHSVPT------PS 1949
Query 340 HTQ---GYRTVQLVWKTLPPFEANGKILDY----------EVTLTRWKSHLQNYTVNATK 386
Q GY +V++ W P G + Y + + + N +
Sbjct 1950 RAQSINGY-SVEVAWNE--PAMVKGVLEKYILKAYSEDSAQPHMPSASTEFNNTDIRTGI 2006
Query 387 LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
LT Y TLT + G ++++ + +A V A N L W+ P
Sbjct 2007 LTGLHPFHSYAVTLTACSRAGCTESSRALSISTPQEAPQEVQAPVAEALPNSLSFFWSPP 2066
Query 447 RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
R++ I ++ + D T Q Y +L Y ITV G +
Sbjct 2067 RQA-NGIITQYSLYMDGRLVYTGKGQN-------YTVTDLRVFTAYEITVGACTRAGCTN 2118
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET 566
+ + Q PP + + ++W Q P + NG + Y ++ N T
Sbjct 2119 SSRVILHTAQLPPERVDPPVLAILDSRTVHIQWKQ-PRQL-NGILERYILYTLNPTHNST 2176
Query 567 AVNVDSSHTE----YTLSSLTSDTLYMVRMAAYTDEG 599
+V + TE + L L+ LY++++ A T G
Sbjct 2177 VWDVVYNSTENLQTHLLYHLSPGCLYLIKLGACTGGG 2213
Score = 41.2 bits (95), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 54/203 (27%), Positives = 84/203 (41%), Gaps = 35/203 (17%)
Query 186 YSTVYFVNIEV--------WVEAENALGKVTSDHINFDPVYKVKPNPPH---NLSVINSE 234
Y T YF++ + ++E N V S + +YK KP NL+ I
Sbjct 1101 YYTQYFLDTSLSPHTAYSYYIETSN----VHSSTRSIPVIYKTKPEGSEGHLNLTHIIPV 1156
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
SI L WT S S I KY + D + P +S T+++L PFT+
Sbjct 1157 ASDSI-TLVWTGLSNHSGPIEKYVLSCTPVDHTE----PCVSYEGPETSATIRNLVPFTQ 1211
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK--APSFWYKIDPSHTQGYRTVQLVWK 352
Y F ++ Y S + T + P + P+ W KI P+ +++ W
Sbjct 1212 YCFSVQGCTNGSCLY----SSPITVTTAQAPPQRQEPPTVW-KISPTE------LKVEWS 1260
Query 353 TLPPFEANGKILDYEVTLTRWKS 375
P ++NG I+ YE+ + RW S
Sbjct 1261 R--PVDSNGVIIRYELYMKRWPS 1281
Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 39/153 (25%), Positives = 65/153 (42%), Gaps = 29/153 (19%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + +INS + +++ WT+PS + +I + ++ + + P SF
Sbjct 3012 PPEVVIINS----TAVRVIWTSPSNPNAVITESSVYANNELHKAGAGAP--------GSF 3059
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI---TYEDRPSKAPSFWYKIDPSHT 341
T++DL PFT Y ++ +D ++SG T ED PS I
Sbjct 3060 TLEDLSPFTIYDIQVEVCTKDA-------CVKSSGTQVSTAEDTPSG-----ISIPIIRD 3107
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK 374
R++Q+ W P NG IL Y+V W+
Sbjct 3108 ITSRSLQIDWTA--PGNPNGIILGYDVLRKTWR 3138
Score = 39.3 bits (90), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 87/401 (22%), Positives = 141/401 (35%), Gaps = 57/401 (14%)
Query 217 VYKVKPNPPHNLSVINSEELSSI---LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
V + PP LS +S+ L ++W P + +I Y +Q A+
Sbjct 4242 VVRTSQAPPDGLSPPEVSYVSTSPLQLLISWFAPRHTNGVIQSYRLQRNGVFAAA----- 4296
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA--PS 331
S+ S+T L PFT Y + + + G G + SE + T E P+ P
Sbjct 4297 --SFNSSTFSYTDGQLLPFTTYSYAV--LACTGGGCCT--SEPTNITTPEASPAGVSPPV 4350
Query 332 FWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL--QNYTVNATKLTV 389
W G + + W PP NGKI Y + + HL Q+ ++ + L
Sbjct 4351 LW-------AIGAHQINVSWS--PPSVPNGKIAKYLLHCDG-EEHLAGQDLSLLLSNLRP 4400
Query 390 NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES 449
+ L T A+ T+ A P + + + W P
Sbjct 4401 FTQYNVSLVACTKGGCTASRVASAWTMEAPPEDMDPPTLHVMGPESIEITWAPPRNPHGQ 4460
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN-----LAESKCYLITVTPVYADGP 504
++ Y L + DG + L L Y TVT + G
Sbjct 4461 IRSYEL----------------RRDGAIVYIGLETRYHDFILTPGVQYGYTVTATNSRGS 4504
Query 505 GSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN 564
+K + PS + + E ++ W+ P NG I NYT+F R ++
Sbjct 4505 VLSPLVKGQTSPSAPSGLQPPKLRAGEALELLVNWN--PPVRTNGKITNYTLFIRELLEG 4562
Query 565 ET-AVNVDSSHTEYTLSSLTSDTL-----YMVRMAAYTDEG 599
E + ++++H+ + SL L Y VR+ A T G
Sbjct 4563 EIRTMCINTTHSSFGTRSLAVKHLKPFHRYEVRVQACTALG 4603
Score = 38.5 bits (88), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 78/343 (23%), Positives = 126/343 (37%), Gaps = 44/343 (13%)
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
SF DL+P T Y +R+ G+G+ S+ T ED P + + +H
Sbjct 3448 SFIDTDLEPSTVYEYRVSVWNSYGRGF----SQSVRASTREDVPQGVTAPRWARTGNHED 3503
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTV 402
+ L WK P ++NG I Y + L + Q ++ T Y L
Sbjct 3504 ---VIFLTWKE--PTQSNGPITHY-ILLRDGRERFQGAALSFTDTQGIQPLQEYSYQLKA 3557
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM-------LWVEWTTPR---ESVKK 452
G +D +C AT L++ P N+ L + W+ P +++K+
Sbjct 3558 CTAAGCAD-------SCKVVATATRGVLESVPPPNITAQSPETLHLSWSVPEKRNDAIKE 3610
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-SIK 511
Y L W L K TD R + L Y T++ + G S E S+
Sbjct 3611 YQL-W--LDGKGLIYTDTNDR-----RQHTVTGLQPHTNYSFTLSACTSVGCTSSEPSVG 3662
Query 512 AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD 571
L+ AP T R + L W+ P + NG I Y + N + + V
Sbjct 3663 QTLQAAPQGVWVTPRHIIINSTTVELYWN--PPERPNGVISQYRLRR-----NGSLLLVG 3715
Query 572 SSHTE-YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKF 613
+ +T +L ++ Y+ + A T G E+ P +
Sbjct 3716 GRDDQSFTDKNLEPNSRYIYTLEARTGGGSSLSEEYLVQMPMW 3758
Score = 38.1 bits (87), Expect = 0.54, Method: Compositional matrix adjust.
Identities = 88/401 (22%), Positives = 151/401 (38%), Gaps = 62/401 (15%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
+PP N++V+ S+ + + W P I ++ K ++Y S + + + R
Sbjct 3764 HPPCNVTVLGSDSIF----VAWPAPGI---LLPKIPVEYSIL-LSGGNMMLLTFSVGLRQ 3815
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
S +++L PFT+Y RI+ +E G G S T E P K SH
Sbjct 3816 SAYLKNLAPFTQYEIRIQACQE-GCGV----SPGTHVRTLEAAPVGLMPPLLKALGSH-- 3868
Query 343 GYRTVQLVWKTLPPFEANGKILDY-----------EVTLTRWKSHLQNYTVNATKLTVNL 391
+++ W PP NG I Y E L W +T + L
Sbjct 3869 ---CIEVKWT--PPTRPNGIITSYVIHRRPADTEEESLLFVWSEGALEFTDDTDTLRPFT 3923
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA----FPKDNMLWVEWTTPR 447
+ + + +V ++V T+ A P DL A + + + WT P
Sbjct 3924 LYEYRVRAWNSKGVVDSPWSSVQTLEA-------PPQDLPAPWVQVTSAHSVLLNWTEP- 3975
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC--------YLITVTPV 499
E+ I ++ V+ + P + TVH ++G+ ++ Y I V V
Sbjct 3976 EAPNGLISQYHVIYQERP--DEAAPGSSTVHAFTVKGSSRQAHLFGLEPFTTYHIGVAAV 4033
Query 500 YADGP-GSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
G SP ++ L+ AP ++ G +L+W + PV NG I+ Y +F
Sbjct 4034 NRAGKVSSPWTLIKTLESAPSGLMNFTAEQREGGRALLLQWSE-PVRT-NGVIKAYNVF- 4090
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
++ ++ L TLY++ + A T G
Sbjct 4091 -----SDGLPEYSGLGRQFLFRRLAPFTLYILTLEACTAAG 4126
Score = 38.1 bits (87), Expect = 0.58, Method: Compositional matrix adjust.
Identities = 36/166 (22%), Positives = 68/166 (41%), Gaps = 27/166 (16%)
Query 240 LKLTWTNPSIKSVIILKYNIQYR---------TKDASTWSQIPPEDTASTRSSFTVQD-- 288
LK+ W+ P + +I++Y + + ++ W P ++ +S +QD
Sbjct 1255 LKVEWSRPVDSNGVIIRYELYMKRWPSTEESLVFESHGWFHSHPASPSANQSENVLQDPQ 1314
Query 289 -------LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
L P TEY FR+ + G S W+ E +G AP F S
Sbjct 1315 VSTVLSGLDPHTEYAFRVLAVNMAGS-VSSAWASERTG-------ESAPVFMAAPSVSPL 1366
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKL 387
Y ++ + W+ G+I+ Y++++ +S ++ V +KL
Sbjct 1367 SPY-SLSVSWEKPAENFTRGEIIGYKISMVSERSPQRDVPVMCSKL 1411
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 55/207 (27%), Positives = 89/207 (43%), Gaps = 23/207 (11%)
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNP-----PHNLSVINSEELSSILKLTWT 245
F EV V+A ALG +S+ + P + P PH + I+ + W
Sbjct 4589 FHRYEVRVQACTALGCTSSE---WTPTQTSEIPPLLQPAPHLEVQTAAGGFQPIVAVWWA 4645
Query 246 NPSIKSVIILKYNIQYRTKDASTW--SQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
P I+++ + YR + AS W + P + SSFT ++L PFTEY +++ +
Sbjct 4646 GPLQPHGKIVRFEL-YRRQTAS-WPGTSSPLLIYNGSLSSFTDRELLPFTEYEYQVWAVN 4703
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
GK S+W+ +G + KAP+F HT + Q V P + NG I
Sbjct 4704 SAGK-VASNWTWCRTGPAPPEG-LKAPTF-------HT--VSSTQAVVNISAPSKPNGNI 4752
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVN 390
+ V +H+ AT+ T++
Sbjct 4753 SLFRVFSNSSGTHVMLSEGMATQQTLH 4779
Score = 36.6 bits (83), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 75/378 (20%), Positives = 145/378 (38%), Gaps = 43/378 (11%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT------VQDLKPFT 293
+++ W P++ ++ KY ++ ++D++ P +AST + T + L PF
Sbjct 1959 VEVAWNEPAMVKGVLEKYILKAYSEDSAQ----PHMPSASTEFNNTDIRTGILTGLHPFH 2014
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
Y + G ++ S S T ++ P + + + P+ ++ W
Sbjct 2015 SYAVTLTACSRAG---CTESSRALSISTPQEAPQEVQAPVAEALPN------SLSFFWS- 2064
Query 354 LPPFEANGKILDYEVTLTR---WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD 410
PP +ANG I Y + + + QNYTV T L V + + T S
Sbjct 2065 -PPRQANGIITQYSLYMDGRLVYTGKGQNYTV--TDLRVFTAYEITVGACTRAGCTNSSR 2121
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES---VKKYILEWCVLSDKAPCI 467
+ T + PV+ A + ++W PR+ +++YIL + + +
Sbjct 2122 VILHTAQLPPERVDPPVL---AILDSRTVHIQWKQPRQLNGILERYIL-YTLNPTHNSTV 2177
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
D +T+L +L+ YLI + G + E +A + + P P R
Sbjct 2178 WDVVYNSTENLQTHLLYHLSPGCLYLIKLGACTGGGCTTSEPSQALMDETVPEGVPAPRA 2237
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDSSHTEYTLSSLTSDT 586
+ + W + NG I Y ++ T+I N + ++ + +
Sbjct 2238 HSHSPDSFNISWTE--PGHPNGVITTYELYLDGTLIHNSSELSCHA-------YGFDPGS 2288
Query 587 LYMVRMAAYTDEGGKDGP 604
L+ ++ A T +G GP
Sbjct 2289 LHTFQVQACTAKGCALGP 2306
Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 48/189 (25%), Positives = 71/189 (38%), Gaps = 21/189 (11%)
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
D + F E V A N+ GKV S+ + P PP L +SS +
Sbjct 4686 DRELLPFTEYEYQVWAVNSAGKVASNWT----WCRTGPAPPEGLKAPTFHTVSSTQAVV- 4740
Query 245 TNPSIKSVIILKYNIQ-YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
+I + NI +R S+ + + + +T+ T+ DL+PFT Y +
Sbjct 4741 ---NISAPSKPNGNISLFRVFSNSSGTHVMLSEGMATQQ--TLHDLRPFTTYAIGVEAC- 4794
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
+ ++ + G T E R AP T G R W PP NG I
Sbjct 4795 -------TCFNCCSRGPTAELRTHPAPPSGLSPPQVQTLGSRMASFQWA--PPQLPNGVI 4845
Query 364 LDYEVTLTR 372
YE+ L R
Sbjct 4846 HSYELQLHR 4854
>sp|Q07409|CNTN3_MOUSE Contactin-3 OS=Mus musculus OX=10090 GN=Cntn3
PE=1 SV=2
Length=1028
Score = 54.3 bits (129), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 99/413 (24%), Positives = 161/413 (39%), Gaps = 48/413 (12%)
Query 217 VYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP--P 274
+ + P PP N+ V E + +L+WT + ++ Y +Q RT + W + P
Sbjct 593 IVRGSPGPPENVKV--DEITDTTAQLSWTEGTDSHSPVISYAVQARTPFSVGWQSVRTVP 650
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
E + TV +L P+ EY FRI + G G S SE+ T E P APS
Sbjct 651 EVIDGKTHTATVVELNPWVEYEFRIVASNKIGGGEPSLPSEKVR--TEEAAPEIAPS--- 705
Query 335 KIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVT-----LTRWKSHLQNYTVNATKLT 388
+ S G R+ + + W +P NG Y V +T W + N +
Sbjct 706 --EVSGGGGSRSELVITWDPVPEELQNGGGFGYVVAFRPLGVTTWIQTVVTSPDNPRYVF 763
Query 389 VN---LTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEW 443
N + Y + V N G+ + V T+ + + + T + A + + V W
Sbjct 764 RNESIVPFSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSHISAHSLSSSEIEVSW 823
Query 444 TT-PRESVKKYILEWCVLSDKAPCITDWQQ--EDGTVHRTYLRGN--------LAESKCY 492
T P + ++L + V W E+ + + + GN L + Y
Sbjct 824 NTIPWKLSNGHLLGYEVRY--------WNNGGEEESSRKVKVAGNQTSAVLRGLKSNLAY 875
Query 493 LITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
V + G G ++ A K+ PPS+ P + +L W+Q+ +
Sbjct 876 YTAVRAYNSAGAGPFSATVNATTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEV 935
Query 552 RNYTIFYRTIIGNETAV-NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
Y +FYRT N V N + + E L + D Y++ + A TD G DG
Sbjct 936 TGYKVFYRTSSQNNVHVLNTNKTSAELLL-PIKED--YIIEVKATTD--GGDG 983
Score = 34.3 bits (77), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 36/130 (28%), Positives = 61/130 (47%), Gaps = 13/130 (10%)
Query 503 GPGSPE--SIKAYLKQAPPSKGPTVRTKKVG-KNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
G G P S K ++A P P+ + G ++E V+ WD +P ++QNG Y + +R
Sbjct 682 GGGEPSLPSEKVRTEEAAPEIAPSEVSGGGGSRSELVITWDPVPEELQNGGGFGYVVAFR 741
Query 560 TIIGNETAVNV-----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFA 614
+G T + D+ + S+ + Y V++ Y ++G +GP F+ T F+
Sbjct 742 P-LGVTTWIQTVVTSPDNPRYVFRNESIVPFSPYEVKVGVYNNKG--EGP-FSPVTTVFS 797
Query 615 QGEIEAIVVP 624
E E V P
Sbjct 798 AEE-EPTVAP 806
>sp|Q2QI47|USH2A_MOUSE Usherin OS=Mus musculus OX=10090 GN=Ush2A
PE=1 SV=2
Length=5193
Score = 54.7 bits (130), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 103/397 (26%), Positives = 155/397 (39%), Gaps = 40/397 (10%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP N++ +SE L L+W+ P I Y + K + DT S R
Sbjct 3586 PPPNITAQSSE----TLHLSWSVPEKMKDAIKAYQLWLDGKG------LIYTDT-SDRRQ 3634
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ- 342
TV L+P+T Y F + G SE G T + P W + P H
Sbjct 3635 HTVTGLQPYTNYSFTLAVCTSVG----CTSSEPCVGQTLQAAPQ---GVW--VTPRHIII 3685
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLT-VNLT-NDRYLATL 400
TV+L W PP NG I Y+ L R S L + T NL RY+ L
Sbjct 3686 NSTTVELYWN--PPERPNGLISQYQ--LRRNGSLLLVGGRDNQSFTDSNLEPGSRYIYKL 3741
Query 401 TVRNLVGKS--DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWC 458
R G S + ++ +P + HP ++ D+ ++V W TP + K +E+
Sbjct 3742 EARTGGGSSWSEDYLVQMPLWTPEDIHPPCNVTVLGSDS-IFVAWPTPGNLLPKIPVEYS 3800
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-SPESIKAYLKQA 517
+L +T +L+ NL+ Y I + G G SP + L+ A
Sbjct 3801 ILLSGGS-VTLLVFSVRHRQSAHLK-NLSPFTQYEIRIQACQNGGCGVSPGTYVRTLEAA 3858
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV--DSSHT 575
P P + K +G + ++W +P NG I +Y + R E ++
Sbjct 3859 PVGLMPPL-LKALGSSCIEVKW--MPPTRPNGIITSYVVHRRPADTEEESLLFVWSEGAL 3915
Query 576 EYT--LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
E+T +L TLY R+ A+ +G D P T T
Sbjct 3916 EFTDDTGTLRPFTLYEYRVRAWNSQGAVDSPWSTIQT 3952
Score = 42.7 bits (99), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 39/141 (28%), Positives = 64/141 (45%), Gaps = 19/141 (13%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
S + LTWT S S + KY + D++ P +S T+ +L PFT+Y
Sbjct 1159 SDSITLTWTGLSNSSDPVAKYVLSCTPVDSTE----PCVSYEGPETSATIWNLVPFTQYC 1214
Query 297 FRIR-CMKEDGKGYWSDWSEEASGITYEDRP-SKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
F ++ C E +S T + P ++ P +KI P+ +++ W
Sbjct 1215 FSVQGCTNES-----CFYSLPIIVTTAQAPPQTQGPPTVWKISPTE------LRIEWS-- 1261
Query 355 PPFEANGKILDYEVTLTRWKS 375
PP ++NG I+ YE+ + RW S
Sbjct 1262 PPVDSNGIIISYELYMRRWLS 1282
Score = 42.0 bits (97), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 48/179 (27%), Positives = 76/179 (42%), Gaps = 22/179 (12%)
Query 196 VWVEAENALGKVTSDHINFDPVYKVKPNPPHNL-SVINSEELSSILKLTWTNPSIKSVI- 253
V V A N+ G V SD ++ + + P P L S + + L++ W+ P+ +
Sbjct 2401 VQVNASNSRGSVLSDPVSVE----MPPGAPDGLLSPRLAAAAPTSLQVVWSTPARNNAPG 2456
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+Y +Q R ST ++ S S+ V L+PFT Y FR+ G Y S W
Sbjct 2457 SPRYQLQMR-PGPSTHGRLELFPIPSASLSYEVTGLQPFTVYEFRLVATNGFGTAY-SAW 2514
Query 314 SEEASGITYEDRPS--KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
+ +T ED+P AP R + ++W+ P + NG I Y + L
Sbjct 2515 TPL---MTTEDKPGPIDAPILI-------NVKARMLSVIWRQ--PAKCNGAITHYNIYL 2561
Score = 42.0 bits (97), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 41/156 (26%), Positives = 67/156 (43%), Gaps = 35/156 (22%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + +INS + +++ WT+PS + ++ + ++ K T + P SF
Sbjct 3016 PPEVVIINS----TAVRVIWTSPSNPNAVVTESSVYVNNKLYKTGTDAP--------GSF 3063
Query 285 TVQDLKPFTEYVFRIR------CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
++DL PFT Y ++ C+K +G + S T ED PS I
Sbjct 3064 VLEDLSPFTIYDIQVEVCTKDACVKSNGT--------QVS--TAEDTPSD-----ISIPV 3108
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK 374
R++Q+ W T P NG IL Y+V W+
Sbjct 3109 IRGITSRSLQIDWTT--PANPNGIILGYDVLRKTWR 3142
Score = 41.6 bits (96), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 74/327 (23%), Positives = 118/327 (36%), Gaps = 38/327 (12%)
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR--T 346
L+PFTEY++R+ E G SDWS G T P P+ PS Q +
Sbjct 1912 LQPFTEYLYRVTASHEGG-AVSSDWSR---GRTLGTAPQSVPT------PSRAQSINGSS 1961
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND----------RY 396
V++ W P G + Y + S +T+L T+ Y
Sbjct 1962 VEVAWNE--PAVVKGVLEKYVLKAYSEDSSQPRVPSASTELHDTSTHSGVLIGLHPFHSY 2019
Query 397 LATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
TLT + G ++++ + +A V A N L W+ PR++ I +
Sbjct 2020 TVTLTACSRAGCTESSQALSISTPQEAPQEVQAPVAVALPNSLSFFWSLPRQA-NGIITQ 2078
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ + D T Q Y +L Y I V G + + + Q
Sbjct 2079 YSLYVDGRLVYTGKGQN-------YTVTDLRVFAAYEIIVGACTQAGCTNSSQVILHTAQ 2131
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
PP + + + W Q P + NG + Y ++ I N T +V + TE
Sbjct 2132 LPPEQVDPPGLTVLDSRTIHVRWKQ-PRQL-NGILERYILYILNPIHNSTMWSVVYNSTE 2189
Query 577 ----YTLSSLTSDTLYMVRMAAYTDEG 599
+ L L+ LY++R+ T G
Sbjct 2190 KLQAHVLHHLSPGGLYLIRLRVCTGGG 2216
Score = 40.8 bits (94), Expect = 0.089, Method: Compositional matrix adjust.
Identities = 68/356 (19%), Positives = 130/356 (37%), Gaps = 41/356 (12%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP-PEDTASTRSSFTVQD---------L 289
++L W+ P+ + I+ Y + R + W D + + + Q L
Sbjct 4163 VRLHWSQPASPNGKIIHYEVIRRRSEEEDWGNTTWQADGNTVFTEYNTQGNAWVYNDTGL 4222
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
+P+ +Y +RI C S W+ + D S + + P +QL
Sbjct 4223 QPWRQYAYRI-CAWNSAGHTCSSWNVVRTLQAPPDGLSPPEISYVSMSP--------LQL 4273
Query 350 VWKTLPPFEANGKILDYEV----TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNL 405
+ LPP +NG I Y + L + ++ ++L T + T
Sbjct 4274 LISWLPPRHSNGVIQGYRLQRDGVLPALNFNASTFSYMDSQLLPFSTYSYAILACTGGGC 4333
Query 406 VGKSDAAVLTIPACDFQATHPVM-DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
+ T + + PV+ D+ A + N+ W + P + KY+L+
Sbjct 4334 CTSEPTNITTPEVPPSEVSPPVLWDISAH-QMNVSWSPPSIPNGKIVKYLLQ-------- 4384
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
D ++ ++L NL S Y I++ + G + + A+ K+APP
Sbjct 4385 ---CDGEEHLAGQGLSFLLSNLQPSTQYNISLVACTSGGCTASRTTSAWTKEAPPENMDP 4441
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLS 580
G + W P +G IR+Y + I V +++ + ++TL+
Sbjct 4442 PTLHITGPESIEITWT--PPRNPHGLIRSYELRRDGAI---VYVGLETRYHDFTLA 4492
Score = 40.4 bits (93), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 91/394 (23%), Positives = 146/394 (37%), Gaps = 57/394 (14%)
Query 224 PPHNLSV--INSEELSSI-LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
PP LS I+ +S + L ++W P + +I Y +Q +D +P + ++
Sbjct 4254 PPDGLSPPEISYVSMSPLQLLISWLPPRHSNGVIQGYRLQ---RDGV----LPALNFNAS 4306
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA--PSFWYKIDP 338
S+ L PF+ Y + I + G G + SE + T E PS+ P W D
Sbjct 4307 TFSYMDSQLLPFSTYSYAI--LACTGGGCCT--SEPTNITTPEVPPSEVSPPVLW---DI 4359
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL--QNYTVNATKLTVNLTNDRY 396
S Q + + W PP NGKI+ Y + + HL Q + + L + +
Sbjct 4360 SAHQ----MNVSWS--PPSIPNGKIVKYLLQCDG-EEHLAGQGLSFLLSNLQPSTQYNIS 4412
Query 397 LATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
L T + T A P + + + W P ++ Y L
Sbjct 4413 LVACTSGGCTASRTTSAWTKEAPPENMDPPTLHITGPESIEITWTPPRNPHGLIRSYEL- 4471
Query 457 WCVLSDKAPCITDWQQEDGTV-----HRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
+ DG + Y LA Y +VT + G +K
Sbjct 4472 ---------------RRDGAIVYVGLETRYHDFTLAPGVEYSYSVTATNSRGSVLSPLVK 4516
Query 512 AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAVNV 570
+ PS + E + +WD P NG I NYT+F R + G A+++
Sbjct 4517 GQTSPSAPSGLQPPKLHSGDALELLADWD--PPVRTNGKIINYTLFVREMFEGKTRAMSI 4574
Query 571 DSSHTEYTLSSLTSDTL-----YMVRMAAYTDEG 599
+++H+ + SLT L Y VR+ A T G
Sbjct 4575 NTTHSSFGTRSLTVKHLKPFHRYEVRVQACTALG 4608
Score = 38.5 bits (88), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 94/403 (23%), Positives = 151/403 (37%), Gaps = 65/403 (16%)
Query 223 NPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
+PP N++V+ S+ + + W P ++ I ++Y+I + + R
Sbjct 3768 HPPCNVTVLGSDSIF----VAWPTPGNLLPKIPVEYSILLSGGSVTLLV-----FSVRHR 3818
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
S +++L PFT+Y RI+ + G G S TY AP + P
Sbjct 3819 QSAHLKNLSPFTQYEIRIQACQNGGCG--------VSPGTYVRTLEAAP---VGLMPPLL 3867
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTL----TRWKSHLQNYTVNATKLTVNLTNDRYL 397
+ + + K +PP NG I Y V T +S L ++ A + T + R
Sbjct 3868 KALGSSCIEVKWMPPTRPNGIITSYVVHRRPADTEEESLLFVWSEGALEFTDDTGTLRPF 3927
Query 398 ATLTVRNLVGKSDAAVLT--------------IPACDFQAT--HPVMDLKAFPKDNMLWV 441
R S AV + +PA QAT H M + W
Sbjct 3928 TLYEYRVRAWNSQGAVDSPWSTIQTLEAPPRGLPAPRVQATSAHSAM---------LNWT 3978
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQE---DGTVHRTYLRGNLAESKCYLITVTP 498
E P + +Y + + D A + GT + +L G L Y I V
Sbjct 3979 EPEAPNGLISQYHVIYQERPDAAAPGSSTVHAFTVTGTSRQAHLFG-LEPFTTYHIGVVA 4037
Query 499 VYADGP-GSPESIKAYLKQAPPS-KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
V + G SP ++ L+ AP TV ++ G+ +L+W + PV NG I+ Y I
Sbjct 4038 VNSAGKVSSPWTLIKTLESAPSGLMNFTVEQREKGR-ALLLQWSE-PVKT-NGVIKAYNI 4094
Query 557 FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
F N+ + ++ L TLY + + A T G
Sbjct 4095 F------NDGVLEYSGLGRQFLFRRLAPFTLYTLILEACTTAG 4131
Score = 38.5 bits (88), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 78/345 (23%), Positives = 120/345 (35%), Gaps = 53/345 (15%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDAS------TWSQIPPEDTASTRSSFTVQDLK 290
SS +++ W P+ + II Y + R D WS+ E T T + L+
Sbjct 3872 SSCIEVKWMPPTRPNGIITSYVVHRRPADTEEESLLFVWSEGALEFTDDTGT------LR 3925
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
PFT Y +R+R G S WS T E P P+ + +H+ L
Sbjct 3926 PFTLYEYRVRAWNSQG-AVDSPWSTIQ---TLEAPPRGLPAPRVQATSAHS-----AMLN 3976
Query 351 WKTLPPFEANGKILDYEVTLTR-------WKSHLQNYTVNATKLTVNLTN----DRYLAT 399
W P NG I Y V S + +TV T +L Y
Sbjct 3977 WTE--PEAPNGLISQYHVIYQERPDAAAPGSSTVHAFTVTGTSRQAHLFGLEPFTTYHIG 4034
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMD--LKAFPKDNMLWVEWTTPRES---VKKYI 454
+ N GK + I + A +M+ ++ K L ++W+ P ++ +K Y
Sbjct 4035 VVAVNSAGKVSSPWTLIKTLE-SAPSGLMNFTVEQREKGRALLLQWSEPVKTNGVIKAYN 4093
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+ D E + R +L LA Y + + G +
Sbjct 4094 I-----------FNDGVLEYSGLGRQFLFRRLAPFTLYTLILEACTTAGCAHSVPQPLWT 4142
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
++APP + VG L W Q P NG I +Y + R
Sbjct 4143 EEAPPDTQMAPTIQSVGPTNVRLHWSQ-PAS-PNGKIIHYEVIRR 4185
Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 47/189 (25%), Positives = 72/189 (38%), Gaps = 19/189 (10%)
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
+D + F E V A N+ GK S+ + P PP L +SS +
Sbjct 4690 MDSELLPFTEYEYQVWAVNSAGKAASNWTRC----RTGPAPPEGLQAPTFHTVSSTRAVV 4745
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
N S+ S ++ +R S+ + + + +T+ T+ DL PFT Y +
Sbjct 4746 --NISVPSRPNGNISL-FRVFSNSSGTHVTLSEGTATQQ--TLHDLSPFTTYTIGVEAC- 4799
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
+ ++ + G T E R AP T G R + W PP NG I
Sbjct 4800 -------TCFNCCSRGPTAELRTHPAPPSGLSPPQVQTLGSRMASVHWT--PPLLPNGVI 4850
Query 364 LDYEVTLTR 372
YE+ L R
Sbjct 4851 HSYELQLQR 4859
Score = 36.2 bits (82), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 77/380 (20%), Positives = 142/380 (37%), Gaps = 41/380 (11%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT----ASTRSSFTVQDLKPF 292
S +++ W P++ ++ KY ++ ++D+S ++P T ST S + L PF
Sbjct 1959 GSSVEVAWNEPAVVKGVLEKYVLKAYSEDSSQ-PRVPSASTELHDTSTHSGVLI-GLHPF 2016
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
Y + G ++ S+ S T ++ P + + P ++ W
Sbjct 2017 HSYTVTLTACSRAG---CTESSQALSISTPQEAPQEVQA------PVAVALPNSLSFFWS 2067
Query 353 TLPPFEANGKILDYEVTLTR---WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
P +ANG I Y + + + QNYTV T L V + + T S
Sbjct 2068 L--PRQANGIITQYSLYVDGRLVYTGKGQNYTV--TDLRVFAAYEIIVGACTQAGCTNSS 2123
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC--I 467
+ T Q P + + + V W PR+ ILE +L P
Sbjct 2124 QVILHTAQLPPEQVDPPGLTVL---DSRTIHVRWKQPRQ--LNGILERYILYILNPIHNS 2178
Query 468 TDWQQEDGTVHR--TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
T W + + ++ +L+ YLI + G + E +A +++ P P
Sbjct 2179 TMWSVVYNSTEKLQAHVLHHLSPGGLYLIRLRVCTGGGCTTSEPSQALMEETIPEGVPAP 2238
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDSSHTEYTLSSLTS 584
R + + W + + NG I Y ++ T+I N + ++ +
Sbjct 2239 RAHSYSPDSFNISWTE--PEYPNGVITTYELYLDDTLIHNSSGLSCHA-------YGFDP 2289
Query 585 DTLYMVRMAAYTDEGGKDGP 604
+L+ ++ A T +G GP
Sbjct 2290 GSLHTFQVQACTAKGCALGP 2309
Score = 36.2 bits (82), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 76/330 (23%), Positives = 124/330 (38%), Gaps = 46/330 (14%)
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS--KAPSFWYKIDPSH 340
SF +DLKP T Y +RI G+G+ S+ T ED P KAP W +
Sbjct 3452 SFIDRDLKPSTVYEYRISAWNSYGRGF----SQSVRASTREDVPEGVKAPR-WARTG--- 3503
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL 400
+ + L W+ P ++NG I+ Y + + Q ++ T+ + + L
Sbjct 3504 -KHEDVIFLQWEE--PMQSNGPIIHY-ILFRDGRERFQG-------TALSFTDTQGIQPL 3552
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM-------LWVEWTTP---RESV 450
+ K+ A +C A + P N+ L + W+ P ++++
Sbjct 3553 QEYSYQLKACTAAGCAVSCKVVAATTQRSPENVPPPNITAQSSETLHLSWSVPEKMKDAI 3612
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
K Y L W L K TD R + L Y T+ + G S E
Sbjct 3613 KAYQL-W--LDGKGLIYTDTSDR-----RQHTVTGLQPYTNYSFTLAVCTSVGCTSSEPC 3664
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
QA P +G V + + N +E P + NG I Y + N + + V
Sbjct 3665 VGQTLQAAP-QGVWVTPRHIIINSTTVELYWNPPERPNGLISQYQLRR-----NGSLLLV 3718
Query 571 DSSHTE-YTLSSLTSDTLYMVRMAAYTDEG 599
+ +T S+L + Y+ ++ A T G
Sbjct 3719 GGRDNQSFTDSNLEPGSRYIYKLEARTGGG 3748
Score = 35.4 bits (80), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 28/105 (27%), Positives = 45/105 (43%), Gaps = 11/105 (10%)
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
APPS + + +G A + W P + NG I +Y + + ++A SHTE
Sbjct 4818 APPSGLSPPQVQTLGSRMASVHWT--PPLLPNGVIHSYELQLQRACPPDSAPRCPPSHTE 4875
Query 577 Y---------TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
+L+ L +T Y V++ AY + G F+T K
Sbjct 4876 RKYWGPGHRASLAGLQPNTAYGVQVVAYNEAGSTASGWTNFSTKK 4920
>sp|Q13332|PTPRS_HUMAN Receptor-type tyrosine-protein phosphatase
S OS=Homo sapiens OX=9606 GN=PTPRS PE=1 SV=3
Length=1948
Score = 53.5 bits (127), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 88/414 (21%), Positives = 150/414 (36%), Gaps = 62/414 (15%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P P NL E S + L+W+ P +S+I KY + +R D T
Sbjct 525 PGQPMNLRAEARSETS--ITLSWSPPRQESII--KYELLFREGDHGREVG----RTFDPT 576
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+S+ V+DLKP TEY FR+ G G ++ + T + +PS P + T
Sbjct 577 TSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQR---TLQSKPSAPPQDVKCVSVRST 633
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS------HLQNYTVNATKLTVNLTND- 394
+ + W+ PP NG ++ Y V S + T++ +
Sbjct 634 ----AILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKW 689
Query 395 -RYLATLTVRNLVG----------KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEW 443
+Y T VG ++D V + P +A ++ A +LW
Sbjct 690 TQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAE--ALNATAI---RVLWRSP 744
Query 444 TTPRE--SVKKYILEWCVL----SDKAPCITD-------WQQEDGTVHRTYLRGNLAESK 490
R+ ++ Y + + + + P I D W+ +D T + NL
Sbjct 745 APGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDD-TAEYEMVITNLQPET 803
Query 491 CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
Y ITV G G+ K + + PT+ ++ + + W+ G
Sbjct 804 AYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEP-----PAGT 858
Query 551 IRNYTIFYRTIIGNETAVNVDS-----SHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ + YR G E + + + S YT S + Y+ R+AA + G
Sbjct 859 AEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAARSRGG 912
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 106/399 (27%), Positives = 162/399 (41%), Gaps = 58/399 (15%)
Query 233 SEELSSILKLTW--TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+E ++ + +TW NP S Y I+Y++K QI ED +TR +++ L
Sbjct 341 TENTATSITITWDSGNPDPVSY----YVIEYKSKSQDGPYQIK-EDITTTR--YSIGGLS 393
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
P +EY + + G+G SE T E P+ AP S T T+ +
Sbjct 394 PNSEYEIWVSAVNSIGQG---PPSESVVTRTGEQAPASAPRNVQARMLSAT----TMIVQ 446
Query 351 WKTLPPFEANGKILDYEVTLTRWKSH----LQNYTVNATKLTV--NLTNDRYLATLTVRN 404
W+ P E NG I Y V T H Q + V+ + LT +L D T TVR
Sbjct 447 WEE--PVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDE---TYTVRV 501
Query 405 LVGKS--DAAVLTIPACDFQATHP--VMDLKAFPK-DNMLWVEWTTPR-ESVKKYILEWC 458
L S D + Q P M+L+A + + + + W+ PR ES+ KY L +
Sbjct 502 LAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFR 561
Query 459 V------LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
+ T + ED + Y A S L TPV ++
Sbjct 562 EGDHGREVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPV----------VRQ 611
Query 513 YLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE----TA 567
Q+ PS P V+ V ++ W P + NG + Y++ YR +G+E
Sbjct 612 RTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRP-LGSEDPEPKE 670
Query 568 VN-VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
VN + + T+ L +L T Y + A+T+ G GPE
Sbjct 671 VNGIPPTTTQILLEALEKWTQYRITTVAHTEVG--PGPE 707
Score = 35.0 bits (79), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 31/121 (26%), Positives = 50/121 (41%), Gaps = 18/121 (15%)
Query 254 ILKYNIQYRTKDASTWS--QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+L Y +Q+ +D++ + + PP + +T + YVFR+ G G
Sbjct 863 VLGYRLQFGREDSTPLATLEFPPSE-----DRYTASGVHKGATYVFRLAARSRGGLG--- 914
Query 312 DWSEEASGITY--EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
EEA+ + ED P P ++ + TV L W P E NG I+ Y V
Sbjct 915 ---EEAAEVLSIPEDTPRGHPQI---LEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVA 968
Query 370 L 370
+
Sbjct 969 V 969
>sp|A2ASS6|TITIN_MOUSE Titin OS=Mus musculus OX=10090 GN=Ttn PE=1
SV=1
Length=35213
Score = 53.1 bits (126), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 114/441 (26%), Positives = 168/441 (38%), Gaps = 36/441 (8%)
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS-SILKLTWTNPSIKSVI 253
E V AENA G + I+ + NPP SV+ + S + + L W P +
Sbjct 30013 EFHVMAENAAGIGPASGISRLIKCREPVNPPSAPSVVKVTDTSKTTVSLEWARPVFDGGM 30072
Query 254 -ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
I+ Y I+ D W ++ E TR +TV DL+ EY FR+ + GKG D
Sbjct 30073 EIIGYIIEMCKADLGDWHKVNTEPCVKTR--YTVTDLQAGEEYKFRVSAVNGAGKG---D 30127
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT-----VQLVWKTLPPFEANGKILDYE 367
E I DR S AP + T R + + ++ P A D
Sbjct 30128 SCEVTGTIKAVDRLS-APELDIDANFKQTHIVRAGVSIRLFIAYQGRPTPTAVWSKPDSN 30186
Query 368 VTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
+++ R H + T N ND TLTV N GK + T+ D
Sbjct 30187 LSI-RADIHTTDSFSTLTVENCN-RNDAGKYTLTVENNSGKK-SITFTVKVLDSPGPPGP 30243
Query 428 MDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNL 486
+ K + + + W P I + V+ + WQ R L+ L
Sbjct 30244 ITFKDVTRGSATLM-WDAPLLDGGARIHHY-VIEKREASRRSWQVVSEKCTRQILKVSEL 30301
Query 487 AESKCYLITVTPVYADGPGS----PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
E Y V+ G G PE I A + APP + V T K+ AVL W L
Sbjct 30302 TEGVPYYFRVSAENEYGVGEPYEMPEPIVATEQPAPPRRLDVVDT---SKSSAVLAW--L 30356
Query 543 PVDVQNG-FIRNYTIFYRTIIGNETAVNVDSSHTE---YTLSSLTSDTLYMVRMAAYTDE 598
D G I +Y + R + V++ HT+ +T+ L +T Y R+ A D
Sbjct 30357 KPDHDGGSRITSYLLEMRQ---KGSDFWVEAGHTKQLTFTVERLVENTEYEFRVKAKNDA 30413
Query 599 GGKDGPEFTFTTPKFAQGEIE 619
G + P F++ + +IE
Sbjct 30414 GYSE-PREAFSSVIIKEPQIE 30433
Score = 53.1 bits (126), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 67/232 (29%), Positives = 93/232 (40%), Gaps = 33/232 (14%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNIQYRTKDASTWSQIPPEDTAST 280
P PP N+++ + + LTW P I Y I+ R K + W DTA T
Sbjct 14980 PGPPLNVTITDVNRFG--VSLTWEPPEYDGGAEITNYVIELRDKTSIRW------DTAMT 15031
Query 281 RS----SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
S TV D+ EY FR+R G G S A+ P + PS +
Sbjct 15032 VRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPS----AATPFVKVADPIERPSPPVNL 15087
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGK-ILDYEVTLTRWKSHLQNYTVNATKLTVNLT--- 392
+ S Q +VQL W+ PP + G IL Y + R + N+ K LT
Sbjct 15088 NASE-QTQSSVQLTWE--PPLKDGGSPILGY--IIERREEGKDNWIRCNMKPVPELTYKV 15142
Query 393 -----NDRYLATLTVRNLVGKSDAAVLTIP-ACDFQATHPVMDLKAFPKDNM 438
++YL ++ N G SD + + P D P MDL AF KD +
Sbjct 15143 TGLQKGNKYLYRVSAENAAGVSDPSEILGPLTADDAFVEPTMDLSAF-KDGL 15193
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 91/394 (23%), Positives = 150/394 (38%), Gaps = 49/394 (12%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK-YNIQYRTKDASTWSQIPPEDTAST 280
P PP NL+V + S +L W P I +K Y I R ++ + +
Sbjct 25905 PGPPQNLAVKEVRKDSVLL--VWEPPIIDGGAKVKNYVIDKRESTRKAYANV---SSKCN 25959
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
++SF V++L Y FR+ E G G ++ S+ P P D S
Sbjct 25960 KTSFRVENLTEGAIYYFRVMAENEFGVGVPTETSDAVKA----SEPPSPPGKVTLTDVSQ 26015
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLT-----RWKSHLQNYTVNATKLTVNLTNDR 395
T + L+W+ P + +IL Y V + +W ++ NA ++ +
Sbjct 26016 T----SASLMWEK-PEHDGGSRILGYVVEMQPKGTEKWSVVAESKVCNAVVSGLS-SGQE 26069
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL 455
Y + N GKSD VL IP DL P + + ++ ++ + +
Sbjct 26070 YQFRVKAYNEKGKSDPRVLGIPVI-------AKDLTIQPSFKLPFNTYSV--QAGEDLKI 26120
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI--------------TVTPVYA 501
E V+ P I+ W + DG + R N+ E+ I +VT +
Sbjct 26121 EIPVIGRPRPKIS-WVK-DGEPLKQTTRVNVEETATSTILHIKESSKDDFGKYSVTATNS 26178
Query 502 DGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR-T 560
G + L++ P GP V+ +V + V+ W+ P I NY + R T
Sbjct 26179 AGTATENLSVIVLEKPGPPVGP-VKFDEVSADFVVISWEP-PAYTGGCQISNYIVEKRDT 26236
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
N V+ + T +S L + T Y R+ A
Sbjct 26237 TTTNWQMVSATVARTTIKISKLKTGTEYQFRIFA 26270
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 106/436 (24%), Positives = 168/436 (39%), Gaps = 68/436 (16%)
Query 198 VEAENALGKVT-SDHINF----DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS- 251
V A NA G S+ NF +P Y P PP V+++ + S + L WT P
Sbjct 31104 VTAVNAAGNSEPSEASNFISCREPSYT--PGPPSAPRVVDTTKRS--ISLAWTKPMYDGG 31159
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSS-FTVQDLKPFTEYVFRIRCMKEDGKGYW 310
I+ Y ++ + KD W ++ A+ R++ FTV DLK +Y FR+ + G
Sbjct 31160 TDIIGYVLEMQEKDTDQWCRV--HTNATIRNNEFTVPDLKMGQKYSFRVAAVNAKG---M 31214
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHT---------------QGYRTVQLVWKTLP 355
SD+SE + I +R + P D T G + + W
Sbjct 31215 SDYSETTAEIEPVER-LEIPDLELADDLKKTVIVRAGASLRLMVSVSGRPSPVITWSKKG 31273
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLA---TLTVRNLVGKSDAA 412
AN I+D + ++Y++ L V+ N RY A T+ N GK A
Sbjct 31274 IDLANRAIID----------NTESYSL----LIVDKVN-RYDAGKYTIEAENQSGKKSAT 31318
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR----ESVKKYILEWCVLSDKAPCIT 468
VL + D P + +K +D++ + W P V YI+E + +
Sbjct 31319 VL-VKVYDTPGPCPSVSVKEVSRDSVT-ITWEIPTIDGGAPVNNYIIE-----KREAAMR 31371
Query 469 DWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPGSP-ESIKAYLKQAPPSKGPTVR 526
++ +T R L E Y V P G G P E+ A L P +
Sbjct 31372 AFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVPTKLE 31431
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYTLSSLT 583
V K+ L W++ P+ + Y + G E V + + E+T+ SL
Sbjct 31432 VVDVTKSTVTLAWEK-PLYDGGSRLTGY-VLEACKAGTERWMKVVTLKPTVLEHTVISLN 31489
Query 584 SDTLYMVRMAAYTDEG 599
Y+ R+ A ++G
Sbjct 31490 EGEQYLFRVRAQNEKG 31505
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 134/568 (24%), Positives = 215/568 (38%), Gaps = 68/568 (12%)
Query 78 QYTIINRTASSVTFT----DIASLNIQLT----CNILTFGQLEQNVYGIT-------IIS 122
Y I R S +++T ++ +LN ++T N F + N YGI +I+
Sbjct 26625 HYIIEKRETSRLSWTQVSNEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEALESEPVIA 26684
Query 123 GLPPEKPK-----NLSCIVNEGKKMRCEW-----DGGRETHLETNFTLKSEWATHKFADC 172
P ++P S I + M W DGG E +E K + ++ C
Sbjct 26685 CNPYKRPGPPSTPEASAITKDS--MVLTWTRPVDDGGAE--IEGYILEKRDKEGIRWTKC 26740
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENA--LGKVTSDHINF---DPVYKVKPNPPHN 227
K T V T + E V AENA +G+ + + + D +Y P PP N
Sbjct 26741 NKKTLTDLRFRVTGLTEGH-SYEFRVAAENAAGVGEPSEPSVFYRACDALYP--PGPPSN 26797
Query 228 LSVINSEELSSILKLTWTNPSIKS-VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 286
V ++ S + L W P + Y I+ + A W+ P + FTV
Sbjct 26798 PKVTDTSRSS--VSLAWNKPIYDGGAPVRGYVIELKKAAADEWTTCTPPSGLQGKQ-FTV 26854
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR- 345
LK TEY FRI +G G + + + ++R +AP D R
Sbjct 26855 TKLKENTEYNFRICAFNTEGVG---EPATIPGSVVAQER-MEAPEIELDADLRKVVTLRA 26910
Query 346 --TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ---NYTVNATKLTVNLTNDRYLATL 400
T++L E K E LT ++ ++ +YT+ + RY L
Sbjct 26911 SATLRLFVTIKGRPEPEVKWEKAEGILTE-RAQIEVTSSYTMLVIDNVTRFDSGRY--NL 26967
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP----RESVKKYILE 456
T+ N G S A + + D + + ++ KD++ + W P + YI+E
Sbjct 26968 TLENNSG-SKTAFVNVRVLDSPSAPVNLTIREVKKDSVT-LSWEPPLIDGGAKITNYIVE 27025
Query 457 WCVLSDKA-PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
+ KA IT + T+ NL E Y V G G P +K
Sbjct 27026 KRETTRKAYATIT-----NNCTKNTFKIENLQEGCSYYFRVLASNEYGIGLPAETAEPVK 27080
Query 516 QAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH 574
+ P P V V +N A ++W++ P I Y + +T + +
Sbjct 27081 VSEPPLPPGRVTLVDVTRNTATIKWEK-PESDGGSKITGYVVEMQTKGSEKWSACTQVKT 27139
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
E T+S LT+ Y+ R+AA ++G D
Sbjct 27140 LETTISGLTAGEEYVFRVAAVNEKGRSD 27167
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 106/457 (23%), Positives = 171/457 (37%), Gaps = 78/457 (17%)
Query 198 VEAENALGKVTSDHINFDPVYKV----KPNPPHNLSVINSEELSSILKLTWTNPSIKS-V 252
+EA N G+ T+ V +V KP PP + + S +L TW P
Sbjct 15552 IEAVNVCGRATA-------VVEVNVLDKPGPPAAFDITDVTNESCLL--TWNPPRDDGGS 15602
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
I Y ++ + D+ W ++ + ++F L P EY+FR+ G G
Sbjct 15603 KITNYVVERKATDSDVWHKL---SSTVKDTNFKATKLTPNKEYIFRVAAENMYGVGE--- 15656
Query 313 WSEEASGIT--YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
+A+ I Y+ P P+ +++PS V L W P + I Y
Sbjct 15657 -PVQAAPIIAKYQFDPPGPPT---RLEPSDIT-KDAVTLTW-CEPDDDGGSPITGY---- 15706
Query 371 TRWKSHLQNYT---VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
W L T V K+ V T R + + A L P ++T P+
Sbjct 15707 --WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSRSTEPI 15764
Query 428 M--------------DLKAFPKDNMLWVEWTTPRE----SVKKYILEWCVLSDKAPCITD 469
+ +K K +++ + WT P ++ Y++E +
Sbjct 15765 LIKDPIDPPWPPGKPTVKDIGKTSLV-LNWTKPEHDGGAKIESYVIEMLKTG-----TDE 15818
Query 470 W-QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP----ESIKAYLKQAPPSKGPT 524
W + +G +L L E + Y V V G P + + K PPS
Sbjct 15819 WVRVAEGVPTTEHLLTGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRW 15878
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI--IGNETAVNVDSSHTEYTLSSL 582
+ + KN A L+W +P I NY + R + G +T V+ T+ T++ L
Sbjct 15879 LEVINITKNTADLKW-TVPEKDGGSPITNYIVEKRDVRRKGWQT-VDTTVKDTKCTVTPL 15936
Query 583 TSDTLYMVRMAA--------YTDEGGKDGPEFTFTTP 611
T +LY+ R+AA YT+ G + TFTTP
Sbjct 15937 TEGSLYVFRVAAENAIGQSDYTEIGDSVLAKDTFTTP 15973
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 140/611 (23%), Positives = 221/611 (36%), Gaps = 94/611 (15%)
Query 77 EQYTIINRTASSVTFTDIASLNIQLT---------CNILTFGQLEQNVYGI--------- 118
+ Y + R S + +T++A+ +Q+T N F + N YG+
Sbjct 23377 DHYIVQKRETSRLAWTNVAT-EVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPV 23435
Query 119 -TIISGLPPEKPKNLSCIVNEGKKMRCEW-----DGGRETHLETNFTL-KSEWATHKFAD 171
+ PP+ PKN M W DGG E N+ + + + A ++
Sbjct 23436 LAVDPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEI---INYIVERRDKAGQRWVK 23492
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKV-----KPNPPH 226
C K T V T E + AENA G S P YK KP PP
Sbjct 23493 CNKKALTDLRFKVSGLTEGH-EYEFRIMAENAAG--ISAPSATSPFYKACDTVFKPGPPG 23549
Query 227 NLSVINSEELSSILKLTWTNPSIKS-VIILKYNIQYRTKDASTWSQI-PPEDTASTRSSF 284
N V+++ S + + W P I Y ++ + W + PP +T S+
Sbjct 23550 NPRVLDTSRSS--ISIAWNKPIYDGGSEITGYMVEIALPEEDEWQVVTPPAGLKAT--SY 23605
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGY 344
T+ L EY RI M +G G + G + P D
Sbjct 23606 TITSLIENQEYKIRIYAMNSEGLGEPA----LVPGTPKAEERMLPPEIELDADLRKVVTI 23661
Query 345 R---TVQLV--WKTLPPFEA-----NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN- 393
R T++L K P E +G+ LD K+ +++ T + T L V N
Sbjct 23662 RACCTLRLFVPIKGRPAPEVKWAREHGESLD--------KASIES-TSSYTLLVVGNVNR 23712
Query 394 -DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP----RE 448
D LTV N G S +A + + D + +K K ++ + W P
Sbjct 23713 FDSGKYILTVENSSG-SKSAFVNVRVLDTPGPPQNLKIKEVTKTSVT-LTWEPPLLDGGS 23770
Query 449 SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC-YLITVTPVYADGPGSP 507
+K YI+E + KA + H+T + + + C Y V G G P
Sbjct 23771 KIKNYIVEKRESTRKA-----YSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLP 23825
Query 508 ----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
ES+KA + PP K + V +N L W++ P I Y + ++
Sbjct 23826 AETAESVKASERPLPPGK---ITLTDVTRNSVSLSWEK-PEHDGGSRILGYIVEMQSKGS 23881
Query 564 NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
+ A TE T++ L Y R++A ++G D + + P A+ +V+
Sbjct 23882 DRWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSV--PVIAKD----LVI 23935
Query 624 PVCLAFLLTTL 634
P L T
Sbjct 23936 PPAFKLLFNTF 23946
Score = 41.6 bits (96), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 95/412 (23%), Positives = 144/412 (35%), Gaps = 59/412 (14%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK-YNIQYRTKDASTWSQIPPEDTAST 280
P PP +L V S+ +L+W P +K Y I+ +T D W+++ P ++T
Sbjct 17701 PGPPKDLKV--SDITRGSCRLSWKMPDDDGGDRIKGYVIEKKTIDGKAWTKVNPNCGSTT 17758
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
F V DL +Y FR+R G G ++ + + P + +
Sbjct 17759 ---FVVPDLISEQQYFFRVRAENRFGIGPPAETIQRTTARDPIYPPDPPIKLKIGLITKN 17815
Query 341 TQGYRTVQLVWKTLPPFEANGK-ILDYEVTLTRWK---------SHLQNYTVNATKLTVN 390
TV L WK PP G + Y V W V + TV
Sbjct 17816 -----TVHLSWK--PPKNDGGSPVTHYIVECLAWDPTGKKKEAWRQCNRRDVEELEFTVE 17868
Query 391 --LTNDRYLATLTVRNLVGKSDAAVLTIPA-CDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
+ Y + N G S + P Q P ++LK F + VE T
Sbjct 17869 DLIEGGEYEFRVKAVNEAGVSKPSATVGPVIVKDQTCPPAIELKEF-----MEVEEGTDV 17923
Query 448 ESVKKY------ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI------- 494
V K L W K P ++ V+ T++ + + C L+
Sbjct 17924 NIVAKIKGVPFPTLTWFKAPPKKP-----DSKEPVVYDTHVNKQVVDDTCTLVIPQSRRS 17978
Query 495 -----TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
++T V G S E L + P GP ++ + + ++ L W P D
Sbjct 17979 DTGLYSITAVNNLGTASKEMRLNVLGRPGPPVGP-IKFESISADQMTLSW-LPPKDDGGS 18036
Query 550 FIRNYTIFYRTIIGNETAVNVDSSHTE--YTLSSLTSDTLYMVRMAAYTDEG 599
I NY I R +T V V S E YT+ L Y+ R+ A G
Sbjct 18037 KITNYVIEKRE-ANRKTWVRVSSEPKECMYTIPKLLEGHEYVFRIMAQNKYG 18087
Score = 41.6 bits (96), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 29/92 (32%), Positives = 43/92 (47%), Gaps = 5/92 (5%)
Query 242 LTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
+ W P S I Y ++ R K + W + E+ T F+VQ+L EY FR++
Sbjct 32632 VAWKPPASDGGAKIRNYYLERREKKQNKWIAVTTEEIRET--VFSVQNLIEGLEYEFRVK 32689
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSF 332
C G+ WS+ SE + D P +AP F
Sbjct 32690 CENLGGESEWSEISEPVT--PKSDVPIQAPHF 32719
Score = 40.0 bits (92), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 88/369 (24%), Positives = 143/369 (39%), Gaps = 51/369 (14%)
Query 195 EVWVEAENALG----KVTSDHINF-DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
E V AENA G TS + DPV+ P+PP +++S + + + + W P
Sbjct 27843 EYRVFAENAAGLSLPSETSPLVRAEDPVFL--PSPPSKPKIVDSGK--TTITIGWVKPLF 27898
Query 250 KS-VIILKYNIQYRTKDASTWSQIPPEDTASTRSS-FTVQDLKPFTEYVFRIRCMKEDGK 307
I Y ++Y+ + + W S R + +T+ L EYVFR+R + + G
Sbjct 27899 DGGAPITGYTVEYKKSEETDWKVA----IQSFRGTEYTMSGLTTGDEYVFRVRSLNKMGA 27954
Query 308 GYWSDWSEEASGITYEDRP------SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
SD S+ E+ P + K S T TV + +P +
Sbjct 27955 SDPSDSSDPQVAKEREEEPVFDVDSEMRKTLIVKAGSSFTM---TVPFRGRPIPNVSWSK 28011
Query 362 KILDYEVTLTRWKSHLQNYTVNATKLTVNLT--NDRYLATLTVRNLVGKSDAAVLTIPAC 419
D R ++++ + T + T LT+ ND TLT++N++ + + +
Sbjct 28012 PDTDL-----RTRAYIDS-TDSRTLLTIENANRNDSGKYTLTIQNVLSAA-SMTFVVKVL 28064
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRES----VKKYILEWCVLSDKAPCITDWQQEDG 475
D + ++ K+ + + W P VK Y +E S KA W
Sbjct 28065 DSPGPPANITVREVTKETAM-LSWDVPENDGGAPVKNYHIEKREASKKA-----WVSVTN 28118
Query 476 TVHR-TYLRGNLAESKCYLITVTPVYADGPGSP----ESIKAYLKQAPPSKGPTVRTKKV 530
+R +Y NL E Y V+ G G P E +K K +PP K + V
Sbjct 28119 NCNRLSYKVTNLQEGAIYYFRVSGENEFGVGVPAETKEGVKITEKPSPPEK---LGVTSV 28175
Query 531 GKNEAVLEW 539
K+ L W
Sbjct 28176 SKDSVSLSW 28184
Score = 39.7 bits (91), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 83/367 (23%), Positives = 148/367 (40%), Gaps = 48/367 (13%)
Query 198 VEAENALGKVTSDHINFDPVYKV-KPNPPHNLSVINSEELSSILKLTWTNPSIKS-VIIL 255
V AEN G V + +P+ +P PP L V+++ + S++L W P I
Sbjct 30311 VSAENEYG-VGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVL--AWLKPDHDGGSRIT 30367
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y ++ R K + W E + + +FTV+ L TEY FR++ + G +S+ E
Sbjct 30368 SYLLEMRQKGSDFWV----EAGHTKQLTFTVERLVENTEYEFRVKAKNDAG---YSEPRE 30420
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV-WKTLPPFEANGKILDYEVTLTRWK 374
S + ++ +I+P+ T QL+ K F + I WK
Sbjct 30421 AFSSVIIKEP---------QIEPTADLTGITNQLITCKAGSTFTIDVPISGRPAPKVTWK 30471
Query 375 SHLQNYTVNAT-KLTVNLTNDRYLATLTVRN------------LVGKSDAAVLTIPACDF 421
L+ + T ++++ T DR TLTV++ L + TI
Sbjct 30472 --LEEMRLKETDRMSIATTKDR--TTLTVKDSMRGDSGRYFLTLENTAGVKTFTITVVVI 30527
Query 422 QATHPV---MDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
PV +++ + ++ + + WT P++ I + ++ + T WQ + +V
Sbjct 30528 GRPGPVTGPIEVSSVSAESCV-LSWTEPKDDGGTEITNY-IVEKRESGTTAWQLINSSVK 30585
Query 479 RTYLR-GNLAESKCYLITVTPVYADGPGSP-ESIKAYLKQ--APPSKGPTVRTKKVGKNE 534
RT ++ +L + K Y V+ G P ES+ + PPS V N
Sbjct 30586 RTQIKVTHLTKYKEYCFRVSSENRFGVSKPLESVPIVAEHPFVPPSAPTRPEVYYVSANA 30645
Query 535 AVLEWDQ 541
+ W++
Sbjct 30646 MSIRWEE 30652
Score = 39.7 bits (91), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 117/503 (23%), Positives = 182/503 (36%), Gaps = 94/503 (19%)
Query 147 DGGRETHLETNFTL-KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
DGG E TN+ + K E + +A A TSCTV+ + + + AEN G
Sbjct 21204 DGGSEI---TNYIIDKRETSRPNWAQVSATVPI-TSCTVE-KLIEGHEYQFRICAENKYG 21258
Query 206 KVTSDHINFDPVYKVKP-NPPHNLSVINSEELSSILK----LTWTNPSIKS-VIILKYNI 259
D I +P P +PP + +S+I K ++W P+ I Y +
Sbjct 21259 --VGDPILTEPAIAKNPYDPPGRC---DPPVISNITKDHMTVSWKAPADDGGSPITGYLV 21313
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ R A W+++ + L+ TEY FR+ + + G G SD AS
Sbjct 21314 EKRETQAVNWTKV--NRKPVIERTLKATGLQEGTEYEFRVTAINKAGPGKPSD----ASK 21367
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRT----VQLVWKTLPPFEANGKILDYEVTLTRWKS 375
Y P P P+ + Y T V L W P ++ I+ Y V + R S
Sbjct 21368 AVYAQDPLYPPG-----PPAFPKVYDTTRSSVSLSWGK-PAYDGGSPIIGYLVEVKRADS 21421
Query 376 ----------HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATH 425
LQ T L + N Y + N +G SD + + C
Sbjct 21422 DHWVRCNLPEKLQKTRFEVTGL---MENTEYQFRVYAVNKIGYSDPSDVPDKHC------ 21472
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV-------LSDKAPCITDWQQEDGTVH 478
PKD ++ E E K IL V + + P W + + +
Sbjct 21473 --------PKDILIPPEGELDAELRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLR 21524
Query 479 R------------TYLRG---NLAESKCYLITVTPVYADGPGSPE---SIKAYLKQAPPS 520
T+LR N ++ Y++T+ + G E +K PP
Sbjct 21525 ERIGLDIKSTDFDTFLRCENVNKYDAGKYILTL----ENSCGKKEYTIVVKVLDTPGPPV 21580
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTL 579
V K+V K+ A + WD +D + I NY + R + V + S T + +
Sbjct 21581 ---NVTVKEVSKDSAYVTWDPPIIDGGSPII-NYVVEKRDAERKSWSTVTTECSKTSFRV 21636
Query 580 SSLTSDTLYMVRMAAYTDEGGKD 602
S+L Y R+ A + G D
Sbjct 21637 SNLEEGKSYFFRVFAENEYGIGD 21659
Score = 39.3 bits (90), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 20/59 (34%), Positives = 31/59 (53%), Gaps = 3/59 (5%)
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ Y ++ R + TWS + PE ++SF V +L P EY FR+ + E G G +D
Sbjct 20519 VTHYIVEKREAERKTWSTVTPE---VKKTSFNVTNLVPGNEYFFRVTAVNEYGPGVPTD 20574
Score = 39.3 bits (90), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 44/163 (27%), Positives = 70/163 (43%), Gaps = 23/163 (14%)
Query 149 GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
G+E T+K++ + A + P S D + VY + +E N LG T
Sbjct 16213 GKEVKASDRLTMKNDHIS-------AHLEVPKSVHAD-AGVYTITLE------NKLGSAT 16258
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNIQYRTKDAS 267
+ IN + P P ++ S+ S KLTW P IL Y ++ R
Sbjct 16259 AS-INVKVIGL--PGPCKDIKA--SDITKSSCKLTWEPPEFDGGSPILHYVLERREAGRR 16313
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
T+ P + + S+TV+DL P EY FR++ + + G G +
Sbjct 16314 TYI---PVMSGENKLSWTVKDLIPNGEYFFRVKAVNKIGGGEY 16353
Score = 38.9 bits (89), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 52/198 (26%), Positives = 76/198 (38%), Gaps = 17/198 (9%)
Query 241 KLTWTNPSIKS-VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
KLTW +P I Y IQ R D W+ P TR + TVQ L Y FRI
Sbjct 18423 KLTWFSPEDDGGSPITNYVIQKREADRRAWT---PVTYTVTRQNATVQGLIQGKSYFFRI 18479
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
G G + E + + D P P ++ TV L W P ++
Sbjct 18480 AAENSIGMG---PFVETPNALVIRD-PITVPERPEDLEVKEVT-KNTVSLTWNP-PKYDG 18533
Query 360 NGKILDY----EVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAAV 413
+I++Y + T + N + + K TV D Y ++ N+VG+ +
Sbjct 18534 GSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSF 18593
Query 414 LTIP-ACDFQATHPVMDL 430
T P C + P +DL
Sbjct 18594 CTKPITCKDELAPPTLDL 18611
Score = 38.9 bits (89), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 9/126 (7%)
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKP----NPPHNLSVINSEELSSILKLTWTNP-SI 249
E V AEN G +++ + DP+ +P PP N + + + S+ L WT P S
Sbjct 19563 EFRVFAENLAG-LSNPSPSSDPIKACRPIKPPGPPINPKLKDKSKESA--DLVWTKPLSD 19619
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
IL Y ++Y+ + W +I +D + +F V L EY FRIR G+G
Sbjct 19620 GGSPILGYVVEYQKPGTAQWDRIN-KDELIRQCAFRVPGLIEGNEYRFRIRAANIVGEGE 19678
Query 310 WSDWSE 315
+ +E
Sbjct 19679 PRELAE 19684
Score = 38.5 bits (88), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 84/372 (23%), Positives = 143/372 (38%), Gaps = 47/372 (13%)
Query 195 EVWVEAENALGKVTSDHINFDPVYK----VKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
E V AEN +G + PV+ KP+PP N I++ + ++LTW P
Sbjct 18872 EFRVSAENEIG-IGDPSPPSKPVFARDPIAKPSPPINPEAIDT--TCNSVELTWQPPRHD 18928
Query 251 S-VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
IL Y ++Y+ W + + + + V L+ Y FR+ + E G+
Sbjct 18929 GGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQSYKFRVLAVNEAGE-- 18986
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR---TVQL--VWKTLPPFEANGKIL 364
SD + + +DR + P + + Q R T++L + K +P + K
Sbjct 18987 -SDPAHVPEPVLVKDR-LEPPELILDANMAREQHIRVGDTLRLSAIIKGVPFPKVTWKKE 19044
Query 365 DYEVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
D E K+ + + T +KL + D + +LTV N G +V +
Sbjct 19045 DREAPT---KAQI-DVTPVGSKLEIRNAAHEDGGIYSLTVENPAGTKTVSVKVL------ 19094
Query 423 ATHPVMDLKAFPKD--------NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED 474
V+D P+D + ++ W P + + + V+ K W
Sbjct 19095 ----VLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVVTNY-VVERKDVATAQWSPLS 19149
Query 475 GTV-HRTYLRGNLAESKCYLITVTP--VYADGP--GSPESIKAYLKQAPPSKGPTVRTKK 529
T ++++ +L E YL V Y GP +P+ IKA PP +
Sbjct 19150 TTSKKKSHMAKHLTEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVD 19209
Query 530 VGKNEAVLEWDQ 541
V K E L W++
Sbjct 19210 VDKTEVSLVWNK 19221
Score = 38.1 bits (87), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 59/231 (26%), Positives = 93/231 (40%), Gaps = 32/231 (14%)
Query 147 DGGRETHLETNFTL-KSEWATHKFADC-KAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
DGG E TN+ L K + +K+ C A + T T + + + V AEN
Sbjct 21892 DGGSEI---TNYVLEKRDSVNNKWVTCASAVQKTTFRVTRLHEGIEYT---FRVSAENKY 21945
Query 205 GKVTSDHINFDPVYKVKP------NPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKY 257
G + + +P+ P PP N+ + + +S LTWT+P I Y
Sbjct 21946 G--VGEGLKSEPIVAKHPFDVPDAPPPPNIVDVRHDSVS----LTWTDPKKTGGSPITGY 21999
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
+I+++ +++ W + T F V L EY FR+ + G G S SE
Sbjct 22000 HIEFKERNSLLWKRA--NKTPIRMKDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPV 22057
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
+ D P K S T+ +V L+W T P ++ K+ Y V
Sbjct 22058 VALDPIDPPGKPEVI------SVTRN--SVTLIW-TEPKYDGGHKLTGYIV 22099
Score = 36.6 bits (83), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 28/113 (25%), Positives = 49/113 (43%), Gaps = 5/113 (4%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK-YNIQYRTKDASTWSQIP 273
DP+Y P PP V ++ S + L W P+ +K Y ++ + + + W +
Sbjct 17489 DPIYP--PGPPSCPEV--KDKTKSSISLAWKPPAKDGGSPIKGYIVEMQEEGTTDWKPVN 17544
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
D T V +LK +Y FR++ + E G+ SD + E ++ P
Sbjct 17545 EPDKLLTACECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEVP 17597
Score = 35.4 bits (80), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 62/238 (26%), Positives = 97/238 (41%), Gaps = 32/238 (13%)
Query 144 CEW-----DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW- 197
C+W DGG E N+TL+ + T +D T +C YS + + +
Sbjct 16609 CKWEPPLDDGGSEI---INYTLEKKDKTKPDSDWIVITSTLRNC--KYSVTKLIEGKEYL 16663
Query 198 --VEAENALGK----VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS 251
V AEN G V+ + DP P+ P V + S ++K W P
Sbjct 16664 FRVRAENRFGPGPPCVSKPLLAKDPFEP--PDAPDKPIVEDVTSNSMLVK--WNEPKDNG 16719
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
IL Y ++ R +++ WS++ +S ++ V L YVFR+ G G +S
Sbjct 16720 SPILGYWLEKREVNSTHWSRVNKTLLSSLKTK--VDGLLEGLTYVFRVCAENAAGPGKFS 16777
Query 312 DWSEEASGITYEDRPSKAPSFWYKI-DPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
S+ T D S ++ D S T T++L W+ P F G+I+ Y V
Sbjct 16778 PPSDPK---TARDPISPPGPPVPRVADTSST----TIELEWEP-PAFNGGGEIMGYFV 16827
Score = 35.0 bits (79), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 33/111 (30%), Positives = 53/111 (48%), Gaps = 10/111 (9%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS-ILKLTWTNP-SIKSVIILKY 257
A+N +G+V D I V+ + P PP I +E+SS + +W P + V I Y
Sbjct 22929 AKNTVGEV-GDVITIQ-VHDI-PGPP--TGPIKFDEVSSDFVTFSWEPPENDGGVPISNY 22983
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
++ R D++TW ++ T R+++ L EY FR+R G G
Sbjct 22984 VVEMRQTDSTTWVELA---TTVIRTTYKATRLTTGVEYQFRVRAQNRYGVG 23031
Score = 34.7 bits (78), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 87/408 (21%), Positives = 156/408 (38%), Gaps = 56/408 (14%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNIQYRTKDASTWSQIPPEDTAST 280
P PP + + +S + S + L W+ P + Y ++ + D W+ + T
Sbjct 28956 PGPPAKIRIADSTKSS--ITLGWSKPVYDGGSDVTGYVVEMKQGDEEEWTIVSTRGEVRT 29013
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
+ + V +LKP Y F++ + G+G +E A + P +
Sbjct 29014 -TEYVVSNLKPGVNYYFQVSAVNCAGQGEPITMTEPAQAKDVLEEPEIDLDVALRTSVIA 29072
Query 341 TQGYRTVQLV--WKTLPP----FEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT-N 393
G VQL+ +K PP + + K L + TR+ +QN ++ + +T N
Sbjct 29073 KAG-EDVQLLIPFKGRPPPTVTWRKDEKNLGSD---TRY--SIQNTDSSSLLVIPQVTRN 29126
Query 394 DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK--AFPKDNMLW----VEWTTPR 447
D LT+ N VG+ ++ +++ D A + +K + +LW ++ +P
Sbjct 29127 DTGKYILTIENGVGQPKSSTVSVKVLDTPAACQKLQVKHVSLGTVTLLWDPPLIDGGSP- 29185
Query 448 ESVKKYILE--------WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPV 499
+ Y++E W V+S K GT ++ +L+E + V
Sbjct 29186 --IINYVIEKRDATKRTWSVVSHKC---------SGT---SFKVTDLSEKTPFFFRVLAE 29231
Query 500 YADGPGSP----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYT 555
G G P E +KA AP + K K VL W + D G I
Sbjct 29232 NEIGIGEPCETTEPVKAAEVPAPIRD---LSMKDSTKTSVVLSWTK--PDFDGGSIITDY 29286
Query 556 IFYRTIIGNETAVNVDSSHT-EYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ R G + + S T E + L ++ R++A ++G D
Sbjct 29287 LVERKGKGEQAWSHAGISKTCEIEIGQLKEQSVLEFRVSARNEKGQSD 29334
>sp|Q14626|I11RA_HUMAN Interleukin-11 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL11RA PE=1 SV=2
Length=422
Score = 52.4 bits (124), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 49/216 (23%), Positives = 82/216 (38%), Gaps = 21/216 (10%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD 177
+T+ G PP +P +SC + + C W + + L T + T AD + +
Sbjct 105 VTLQLGYPPARPV-VSCQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSP 163
Query 178 T--PTSCTVD---------YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH 226
+ P C D + ++ + V N LG T ++ ++P+PP
Sbjct 164 STGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGASTR-LLDVSLQSILRPDPPQ 222
Query 227 NLSVINSEELSSILKLTWTNPS---IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
L V + L+ +WT P+ + +LK+ +QYR WS + P
Sbjct 223 GLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEE---- 278
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ D + R+ G WS WS EA G
Sbjct 279 -VITDAVAGLPHAVRVSARDFLDAGTWSTWSPEAWG 313
>sp|Q5RF19|I11RA_PONAB Interleukin-11 receptor subunit alpha OS=Pongo
abelii OX=9601 GN=IL11RA PE=2 SV=1
Length=422
Score = 51.6 bits (122), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 54/239 (23%), Positives = 89/239 (37%), Gaps = 24/239 (10%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD 177
+T+ G PP +P +SC + + C W + + L T + T AD + +
Sbjct 105 VTLQLGYPPARPV-VSCQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSP 163
Query 178 T--PTSCTVD---------YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH 226
+ P C D + ++ + V N LG T ++ ++P+PP
Sbjct 164 STGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGASTR-LLDVSLQSILRPDPPQ 222
Query 227 NLSVINSEELSSILKLTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
L V + L+ +WT P+ + +LK+ +QYR WS + P
Sbjct 223 GLRVESVPGYPRRLRASWTYPASWPRQPHFLLKFRLQYRPAQHPAWSTVEPAGLEE---- 278
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
+ D + R+ G WS WS EA G K W ++ HTQ
Sbjct 279 -VITDAVAGLPHAVRVSARDFLDAGTWSTWSPEAWGTPSTGTVPKEIPAWGQL---HTQ 333
>sp|Q61772|EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus musculus
OX=10090 GN=Epha7 PE=1 SV=2
Length=998
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 58/220 (26%), Positives = 92/220 (42%), Gaps = 27/220 (12%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW-----DGGRETHLETNFTLKSEWATHKFADCKAK---R 176
PP P+NL +N+ + EW +GGR + W + C +
Sbjct 331 PPSAPQNLIFNINQ-TTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYM 389
Query 177 DTPTSCTVDYSTVY----FVNIEVWVEAENALGKVTSDHINFDPVYKV--KPNPPHNLSV 230
T +Y TV N VEA N + ++ F V + P V
Sbjct 390 PQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGV 449
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS--TWSQIPPEDTASTRSSFTVQD 288
+ L ++L+W P + +I +Y I+Y KD T+S + + T+++ + +
Sbjct 450 MKERVLQRSVQLSWQEPEHPNGVITEYEIKYYEKDQRERTYSTLKTKSTSAS-----INN 504
Query 289 LKPFTEYVFRIRCMKEDGKGYWS---DWS--EEASGITYE 323
LKP T YVF+IR + G G +S D + EEASG +E
Sbjct 505 LKPGTVYVFQIRAVTAAGYGNYSPRLDVATLEEASGKMFE 544
>sp|O75445|USH2A_HUMAN Usherin OS=Homo sapiens OX=9606 GN=USH2A
PE=1 SV=3
Length=5202
Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 100/418 (24%), Positives = 152/418 (36%), Gaps = 75/418 (18%)
Query 224 PPHNLS--VINSEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
PP LS VI+ ++ L ++W P + II Y +Q + P
Sbjct 4262 PPEGLSPPVISYVSMNPQKLLISWIPPEQSNGIIQSYRLQRN-------EMLYPFSFDPV 4314
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA--PSFWYKIDP 338
++T ++L PF+ Y + ++ G S+ S T E PS+ P W
Sbjct 4315 TFNYTDEELLPFSTYSYALQACTSGG----CSTSKPTSITTLEAAPSEVSPPDLWAV--- 4367
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVT-----------LTRWKSHLQNYTVNATKL 387
S TQ + + W PP NGKI Y V L SHLQ Y+ L
Sbjct 4368 SATQ----MNVCWS--PPTVQNGKITKYLVRYDNKESLAGQGLCLLVSHLQPYSQYNFSL 4421
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
V TN A+ V KS + +P P + + + W P
Sbjct 4422 -VACTNGGCTAS------VSKSAWTMEALPE---NMDSPTLQVTGSESIEITWKPPRNPN 4471
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT-----YLRGNLAESKCYLITVTPVYAD 502
++ Y L + DGT+ T Y L Y TVT +
Sbjct 4472 GQIRSYEL----------------RRDGTIVYTGLETRYRDFTLTPGVEYSYTVTASNSQ 4515
Query 503 GPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII 562
G +K + PS + + G E ++ WD P NG I NYT+F R +
Sbjct 4516 GGILSPLVKDRTSPSAPSGMEPPKLQARGPQEILVNWD--PPVRTNGDIINYTLFIRELF 4573
Query 563 GNETA-VNVDSSHTEYTLSSLTSDTL-----YMVRMAAYTDEGGKDGPEFTFTTPKFA 614
ET ++++++H + + S + L Y +R+ A T G TP+ A
Sbjct 4574 ERETKIIHINTTHNSFGMQSYIVNQLKPFHRYEIRIQACTTLGCASSDWTFIQTPEIA 4631
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 41/155 (26%), Positives = 69/155 (45%), Gaps = 35/155 (23%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + +INS + +++ WT+PS + ++ +Y+I K T +P SF
Sbjct 3025 PPEVVIINS----TAVRVIWTSPSNPNGVVTEYSIYVNNKLYKTGMNVP--------GSF 3072
Query 285 TVQDLKPFTEYVFRIR------CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
++DL PFT Y ++ C+K +G T ED PS P+ +
Sbjct 3073 ILRDLSPFTIYDIQVEVCTIYACVKSNGTQI----------TTVEDTPSDIPTPTIRGIT 3122
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
S R++Q+ W + P + NG IL Y++ W
Sbjct 3123 S-----RSLQIDW--VSPRKPNGIILGYDLLWKTW 3150
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 20/185 (11%)
Query 189 VYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHN-LSVINSEELSSILKLTWTNP 247
V F N V V N+ G + +D I + P P L S + L++ W+ P
Sbjct 2403 VPFTNYTVQVNISNSQGSLITDPITI----AMPPGAPDGVLPPRLSSATPTSLQVVWSTP 2458
Query 248 SIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ + +Y +Q R+ D ST + S S+ V DL+P+TEY+FR+
Sbjct 2459 ARNNAPGSPRYQLQMRSGD-STHGFLELFSNPSASLSYEVSDLQPYTEYMFRL----VAS 2513
Query 307 KGYWSDWSEEASGITYEDRPSK-APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G+ S S +T ED+P P + R + + W+ P ++NG I
Sbjct 2514 NGFGSAHSSWIPFMTAEDKPGPVVPPILLDVKS------RMMLVTWQH--PRKSNGVITH 2565
Query 366 YEVTL 370
Y + L
Sbjct 2566 YNIYL 2570
Score = 43.9 bits (102), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 81/333 (24%), Positives = 130/333 (39%), Gaps = 37/333 (11%)
Query 236 LSSI-LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
LS++ L L+W+ P + +I +Y I+ K + DT + R TV L+P+T
Sbjct 3601 LSAVALHLSWSVPEKSNGVIKEYQIRQVGKG------LIHTDT-TDRRQHTVTGLQPYTN 3653
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH-TQGYRTVQLVWKT 353
Y F + G SE G T + P W + P H TV+L W
Sbjct 3654 YSFTLTACTSAG----CTSSEPFLGQTLQAAPE---GVW--VTPRHIIINSTTVELYWSL 3704
Query 354 LPPFEANGKILDYEVT-----LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK 408
P + NG + Y+++ L S QN+T + N RY L V+ G
Sbjct 3705 --PEKPNGLVSQYQLSRNGNLLFLGGSEEQNFTDKNLE-----PNSRYTYKLEVKTGGGS 3757
Query 409 --SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
SD ++ P + +P ++ ++V W P + + +E+ VL +
Sbjct 3758 SASDDYIVQTPMSTPEEIYPPYNITVI-GPYSIFVAWIPPGILIPEIPVEYNVLLNDGS- 3815
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVR 526
+T G H++ L NL Y I + G + +A P +
Sbjct 3816 VTPLAFSVGH-HQSTLLENLTPFTQYEIRIQACQNGSCGVSSRMFVKTPEAAPMDLNSPV 3874
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
K +G A +E +P + NG I NY I+ R
Sbjct 3875 LKALGS--ACIEIKWMPPEKPNGIIINYFIYRR 3905
Score = 39.7 bits (91), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 52/204 (25%), Positives = 84/204 (41%), Gaps = 37/204 (18%)
Query 186 YSTVYFVNIEV--------WVEAENALGKVTSDHINFDPVYKVKPNPPH-NLSV-----I 231
YS YF++ ++ ++E N G S + YK KP P NL++ I
Sbjct 1105 YSIQYFLDTDLLPYTKYSYYIETTNVHGSTRSVAV----TYKTKPGVPEGNLTLSYIIPI 1160
Query 232 NSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
S+ ++ LTWT S +S I KY + A P +S T+ +L P
Sbjct 1161 GSDSVT----LTWTTLSNQSGPIEKYILSC----APLAGGQPCVSYEGHETSATIWNLVP 1212
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
F +Y F ++ G + S + T + P + + P Q + +L
Sbjct 1213 FAKYDFSVQACTSGGCLH----SLPITVTTAQAPPQR-------LSPPKMQKISSTELHV 1261
Query 352 KTLPPFEANGKILDYEVTLTRWKS 375
+ PP E NG I+ YE+ + R +S
Sbjct 1262 EWSPPAELNGIIIRYELYMRRLRS 1285
Score = 37.4 bits (85), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 38/144 (26%), Positives = 60/144 (42%), Gaps = 17/144 (12%)
Query 242 LTWTNPSIKSVIILKYNIQYRTK---DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
++W P+ + ++ + I+ R K + +T +P + S R L P+T+Y +R
Sbjct 2642 ISWQPPTHPNGLVENFTIERRVKGKEEVTTLVTLP--RSHSMRFIDKTSALSPWTKYEYR 2699
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKA-PSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
+ G S W E T RP+ P ++P VQ+ WK PP
Sbjct 2700 VLMSTLHGGTNSSAWVEVT---TRPSRPAGVQPPVVTVLEPD------AVQVTWK--PPL 2748
Query 358 EANGKILDYEVTLTRWKSHLQNYT 381
NG IL YE+ + L N T
Sbjct 2749 IQNGDILSYEIHMPDPHITLTNVT 2772
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 43/190 (23%), Positives = 70/190 (37%), Gaps = 33/190 (17%)
Query 191 FVNIEVWVEAENALGKVTSD--HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
F E+ ++A LG +SD I + + PPH + + L WT P
Sbjct 4602 FHRYEIRIQACTTLGCASSDWTFIQTPEIAPLMQPPPHLEVQMAPGGFQPTVSLLWTGPL 4661
Query 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
+ +L Y + R P + +SF +L PFTEY +++
Sbjct 4662 QPNGKVLYYELYRRQIATQPRKSNPVLIYNGSSTSFIDSELLPFTEYEYQV--------- 4712
Query 309 YWSDWSEEASGITYEDRPSKAPS--FWYKIDPSHTQGYR--------TVQLVWKTLPPFE 358
W+ ++G KAPS W + P+ +G R + Q V P +
Sbjct 4713 ----WAVNSAG--------KAPSSWTWCRTGPAPPEGLRAPTFHVISSTQAVVNISAPGK 4760
Query 359 ANGKILDYEV 368
NG + Y +
Sbjct 4761 PNGIVSLYRL 4770
Score = 36.6 bits (83), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 28/85 (33%), Positives = 40/85 (47%), Gaps = 11/85 (13%)
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK-APSFWYKIDPSHT 341
S+T +LKP+ Y +RI G+G S+ T ED P +P W KID
Sbjct 3460 SYTDVNLKPYMTYEYRISAWNSYGRGL----SKAVRARTKEDVPQGVSPPTWTKIDNLED 3515
Query 342 QGYRTVQLVWKTLPPFEANGKILDY 366
T+ L W+ P ++NG I+ Y
Sbjct 3516 ----TIVLNWRK--PIQSNGPIIYY 3534
Score = 35.4 bits (80), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 29/125 (23%), Positives = 49/125 (39%), Gaps = 9/125 (7%)
Query 438 MLWVEWTTPRESVKKYILEWCVLSDKAPCIT-DWQQEDGTVHRTYLRGNLAESKCYLITV 496
+ W + ++KYIL L+ PC++ + + T+ NL Y +V
Sbjct 1167 LTWTTLSNQSGPIEKYILSCAPLAGGQPCVSYEGHETSATIW------NLVPFAKYDFSV 1220
Query 497 TPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
+ G I QAPP + + +K+ E +EW P NG I Y +
Sbjct 1221 QACTSGGCLHSLPITVTTAQAPPQRLSPPKMQKISSTELHVEWS--PPAELNGIIIRYEL 1278
Query 557 FYRTI 561
+ R +
Sbjct 1279 YMRRL 1283
Score = 35.4 bits (80), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 80/345 (23%), Positives = 122/345 (35%), Gaps = 45/345 (13%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
S+ +++ W P + II+ Y I R S + + L+PFT Y
Sbjct 3880 SACIEIKWMPPEKPNGIIINYFIYRRPAGIEEESVLFVWSEGALEFMDEGDTLRPFTLYE 3939
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
+R+R G S WS T E P P+ W + +H +V L W P
Sbjct 3940 YRVRACNSKGS-VESLWSLTQ---TLEAPPQDFPAPWAQATSAH-----SVLLNWTK--P 3988
Query 357 FEANGKILDYEVTL-------TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
NG I Y V T + +TV T +L T + +V +
Sbjct 3989 ESPNGIISHYRVVYQERPDDPTFNSPTVHAFTVKGTSHQAHLYGLEPFTTYRI-GVVAAN 4047
Query 410 DAAVLTIPACDFQATHPV-MDLKAF---PKDN--MLWVEWTTPRES---VKKYILEWCVL 460
A + P Q L+ F K+N L ++W+ P + +K Y +
Sbjct 4048 HAGEILSPWTLIQTLESSPSGLRNFIVEQKENGRALLLQWSEPMRTNGVIKTYNI----- 4102
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS 520
+D E ++R +L L Y +T+ G + +APP
Sbjct 4103 ------FSDGFLEYSGLNRQFLFRRLDPFTLYTLTLEACTRAGCAHSAPQPLWTDEAPPD 4156
Query 521 K--GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
PTV + K E L W + PV+ NG I Y + R G
Sbjct 4157 SQLAPTVHSVKSTSVE--LSWSE-PVN-PNGKIIRYEVIRRCFEG 4197
Score = 35.4 bits (80), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 31/93 (33%), Positives = 41/93 (44%), Gaps = 20/93 (22%)
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
S+ V LKPF Y RI+ G SDW T+ P AP P H +
Sbjct 4593 SYIVNQLKPFHRYEIRIQACTTLGCAS-SDW-------TFIQTPEIAPLMQ---PPPHLE 4641
Query 343 ------GYR-TVQLVWKTLPPFEANGKILDYEV 368
G++ TV L+W P + NGK+L YE+
Sbjct 4642 VQMAPGGFQPTVSLLWTG--PLQPNGKVLYYEL 4672
Score = 34.7 bits (78), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 82/394 (21%), Positives = 148/394 (38%), Gaps = 49/394 (12%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
PP+N++VI + + W P I I ++YN+ D S P +
Sbjct 3777 PPYNITVIGPYSIF----VAWIPPGILIPEIPVEYNVLL--NDGSV---TPLAFSVGHHQ 3827
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
S +++L PFT+Y RI+ + G S + P AP ++ +
Sbjct 3828 STLLENLTPFTQYEIRIQACQNGSCG--------VSSRMFVKTPEAAP---MDLNSPVLK 3876
Query 343 GYRTVQLVWKTLPPFEANGKILDYEV----TLTRWKSHLQNYTVNATKLTVNLTNDRYLA 398
+ + K +PP + NG I++Y + +S L ++ A + R
Sbjct 3877 ALGSACIEIKWMPPEKPNGIIINYFIYRRPAGIEEESVLFVWSEGALEFMDEGDTLRPFT 3936
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA----FPKDNMLWVEWTTPRESVKKYI 454
R S +V ++ + P D A + + + WT P ES I
Sbjct 3937 LYEYRVRACNSKGSVESLWSLTQTLEAPPQDFPAPWAQATSAHSVLLNWTKP-ESPNGII 3995
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI------TVTPVYADGPG--- 505
+ V+ + P D TVH ++G ++ Y + + V A+ G
Sbjct 3996 SHYRVVYQERP--DDPTFNSPTVHAFTVKGTSHQAHLYGLEPFTTYRIGVVAANHAGEIL 4053
Query 506 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE 565
SP ++ L+ +P + +K +L+W + P+ NG I+ Y IF ++
Sbjct 4054 SPWTLIQTLESSPSGLRNFIVEQKENGRALLLQWSE-PMRT-NGVIKTYNIF------SD 4105
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ + ++ L TLY + + A T G
Sbjct 4106 GFLEYSGLNRQFLFRRLDPFTLYTLTLEACTRAG 4139
>sp|P22272|IL6RA_MOUSE Interleukin-6 receptor subunit alpha OS=Mus
musculus OX=10090 GN=Il6ra PE=1 SV=2
Length=460
Score = 51.2 bits (121), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 57/235 (24%), Positives = 95/235 (40%), Gaps = 36/235 (15%)
Query 118 ITIISGLPPEKPKNLSCIV-NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKR 176
+ ++ +PPE+PK LSC N CEW T L ++ K K
Sbjct 102 VPLLVDVPPEEPK-LSCFRKNPLVNAICEWRPSSTPSPTTKAVLFAK----KINTTNGKS 156
Query 177 DTPTSC--------------TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 222
D C ++ VY + V + N++G +S + F + V+P
Sbjct 157 DFQVPCQYSQQLKSFSCQVEILEGDKVYHI---VSLCVANSVGSKSSHNEAFHSLKMVQP 213
Query 223 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTA-- 278
+PP NL V LK++W +P S +L++ ++YR WS+ E T
Sbjct 214 DPPANLVVSAIPGRPRWLKVSWQHPETWDPSYYLLQFQLRYR----PVWSK---EFTVLL 266
Query 279 --STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
+ + D ++V ++R +E G WS+WS E +G + P P+
Sbjct 267 LPVAQYQCVIHDALRGVKHVVQVRGKEELDLGQWSEWSPEVTGTPWIAEPRTTPA 321
>sp|Q8AV57|SDK2_CHICK Protein sidekick-2 OS=Gallus gallus OX=9031
GN=SDK2 PE=1 SV=2
Length=2177
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 110/460 (24%), Positives = 180/460 (39%), Gaps = 62/460 (13%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P PP + ++ E ++ ++L W P+ + IIL Y + +R + + + STR
Sbjct 1306 PGPP--VGMLFPEVRTTSVRLIWQPPTAPNGIILAYQLTHRLNTTTANAAVSEVLGPSTR 1363
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+T L+P Y+F I G W + + EA +T E R P +
Sbjct 1364 Q-YTATGLQPEATYLFSITAQTRKG---WGE-AAEALVVTTEKRDRPQPPSKPLVRQEDV 1418
Query 342 QGYRTVQLVWKTLPPFEANGKILDY-----EVTLTRWKSHLQNYTVNATKLTVNLTND-- 394
+ R+V L W+ P + + Y E+ W H + + NAT V+
Sbjct 1419 RA-RSVLLSWE--PGSDGLSPVRFYTVQTRELPSGEWALHPASISHNATAFVVDRLKPFT 1475
Query 395 ----RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV 450
R AT + + ++ LT + ++ + ++L + W P E
Sbjct 1476 SYKFRVKATNDIGDSEYSEESESLTTLQAAPEEAPTILSVTPHTTTSVL-IRWQPPSEDK 1534
Query 451 KKYILEWC------VLSDKAPCIT---------DWQQEDG--TVHRT-------YLRGNL 486
IL +L D T W + VH Y NL
Sbjct 1535 INGILLGFRLRYRELLYDSLRGFTLHGIGNPGATWAELTPVYAVHNLSEVSLTQYELDNL 1594
Query 487 AESKCYLITVTPVY---ADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQL 542
++ + Y I ++ VY +GP SP + ++ +A P+ P V K + + W+
Sbjct 1595 SKHRRYEIRMS-VYNAVGEGPPSPPQ-EVFVGEAMPTGAPQNVAVKAATATQLDVTWEPP 1652
Query 543 PVDVQNGFIRNYTI-FYRTIIGNETAV--NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
P + QNG I+ Y I F+ NE+A + T L +LT T Y V +AA+ G
Sbjct 1653 PTESQNGDIQGYKIHFWEAQRQNESARVKTLFLPETGVKLKNLTGYTSYWVSIAAFNAAG 1712
Query 600 GKDGPEFTFTTPKFAQGEIEAIVVPVCLAF--LLTTLLGV 637
DGP +TP A+ + A P + F L TT + V
Sbjct 1713 --DGPR---STPVTARTQQAAPSAPGSIRFSELTTTSVNV 1747
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 88/342 (26%), Positives = 132/342 (39%), Gaps = 44/342 (13%)
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+T++DL+ +TEY +++ G G WS G T E PS PS + T
Sbjct 1165 YTIEDLEEWTEYRVQVQAFNAIGSG---PWSHLVLGRTRESVPSSGPS---NVSAQATSS 1218
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH-------LQNYTVNATKLT----VNLT 392
+ + W +P + NG IL Y+V S + T + +LT L
Sbjct 1219 SNML-VRWSDIPEADCNGLILGYKVMFKEKDSEARAQFWLAEGNTSRSAQLTGLGKFMLY 1277
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK-----DNMLWVEWTTPR 447
R LA + + V S +L D PV L FP+ ++W T P
Sbjct 1278 EIRVLAFTRIGDGV-PSRPPILERTLDDVPGP-PVGML--FPEVRTTSVRLIWQPPTAPN 1333
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
+ Y L + + A + G R Y L YL ++T G G
Sbjct 1334 GIILAYQLTHRLNTTTANAAVS--EVLGPSTRQYTATGLQPEATYLFSITAQTRKGWG-- 1389
Query 508 ESIKAYL-------KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
E+ +A + + PPSK P VR + V +L W+ P +R YT+ R
Sbjct 1390 EAAEALVVTTEKRDRPQPPSK-PLVRQEDVRARSVLLSWE--PGSDGLSPVRFYTVQTRE 1446
Query 561 IIGNETAVNVDS-SH--TEYTLSSLTSDTLYMVRMAAYTDEG 599
+ E A++ S SH T + + L T Y R+ A D G
Sbjct 1447 LPSGEWALHPASISHNATAFVVDRLKPFTSYKFRVKATNDIG 1488
Score = 42.4 bits (98), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 108/459 (24%), Positives = 177/459 (39%), Gaps = 83/459 (18%)
Query 197 WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK 256
W EA AL VT++ + +P PP V + + + L+W S +
Sbjct 1388 WGEAAEAL-VVTTEK-------RDRPQPPSKPLVRQEDVRARSVLLSWEPGSDGLSPVRF 1439
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y +Q R + W+ + P + ++F V LKPFT Y FR++ + G +S+ SE
Sbjct 1440 YTVQTRELPSGEWA-LHPASISHNATAFVVDRLKPFTSYKFRVKATNDIGDSEYSEESES 1498
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE--ANGKILDYEVTLTRWK 374
+ T + P +AP+ + P T +V + W+ PP E NG +L + + R++
Sbjct 1499 LT--TLQAAPEEAPTI-LSVTPHTTT---SVLIRWQ--PPSEDKINGILLGFRL---RYR 1547
Query 375 S----HLQNYTVNA--------TKLT----------VNLT---------NDRYLATLTVR 403
L+ +T++ +LT V+LT + RY ++V
Sbjct 1548 ELLYDSLRGFTLHGIGNPGATWAELTPVYAVHNLSEVSLTQYELDNLSKHRRYEIRMSVY 1607
Query 404 NLVGKSDAA----VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR--------ESVK 451
N VG+ + V A A V A L V W P + K
Sbjct 1608 NAVGEGPPSPPQEVFVGEAMPTGAPQNVAVKAA--TATQLDVTWEPPPTESQNGDIQGYK 1665
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-- 509
+ E ++ A T + E G + NL Y +++ A G G P S
Sbjct 1666 IHFWEAQRQNESARVKTLFLPETGVKLK-----NLTGYTSYWVSIAAFNAAGDG-PRSTP 1719
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII---GNET 566
+ A +QA PS ++R ++ + W+ P + NG + Y + Y + G
Sbjct 1720 VTARTQQAAPSAPGSIRFSELTTTSVNVSWE--PPPLPNGILEGYRLVYEPCMPVDGVSK 1777
Query 567 AVNVD---SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
V VD +S + L Y R+ A T G D
Sbjct 1778 IVTVDVKGNSPLWMKVKDLAEGITYRFRIRAKTFAYGPD 1816
Score = 39.7 bits (91), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 94/419 (22%), Positives = 154/419 (37%), Gaps = 71/419 (17%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI---QYRTKDASTWSQIPPEDTA 278
P P +LS SE L + LK++W P K+ I+ Y I +Y + +P
Sbjct 900 PGPVGHLSF--SEILDTSLKVSWQEPLEKNGILTGYRISWEEYNRTNTRVTHYLP----- 952
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+ + V L T Y + M G+G S S +SG+ P + P +
Sbjct 953 NVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSS-STISSGV-----PPELPGAPTNLGI 1006
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL---QNYTVNATKLTVNLTNDR 395
S+ G R+V L ++ P + D + +++RW+ QN L L N+
Sbjct 1007 SNI-GPRSVTLQFR--PGY-------DGKTSISRWQVEAQVGQNGEAEEWGLVHQLANEP 1056
Query 396 YLATLTVRNL---------------VGKSDAAVLTIPACDFQATHPVMDLKAFPK---DN 437
+L V NL VG S ++ + QA V + +
Sbjct 1057 DARSLEVPNLNPYTYYSFRMRQVNIVGTSPPSLPSRRIQTLQAPPDVAPANVTLRTASET 1116
Query 438 MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG-----------TVHRTYLRGNL 486
LW+ W E E+ D + + DG V R Y +L
Sbjct 1117 SLWLRWMPLLEQ------EYNGNPDSVGYRIRYLRSDGQGRAVVHVIHDRVEREYTIEDL 1170
Query 487 AESKCYLITVTPVYADGPGSPES--IKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLP 543
E Y + V A G G P S + +++ PS GP+ V + + ++ W +P
Sbjct 1171 EEWTEYRVQVQAFNAIGSG-PWSHLVLGRTRESVPSSGPSNVSAQATSSSNMLVRWSDIP 1229
Query 544 VDVQNGFIRNYTIFYRTIIGNETA---VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
NG I Y + ++ A + ++ L+ L LY +R+ A+T G
Sbjct 1230 EADCNGLILGYKVMFKEKDSEARAQFWLAEGNTSRSAQLTGLGKFMLYEIRVLAFTRIG 1288
>sp|P54759|EPHA7_RAT Ephrin type-A receptor 7 OS=Rattus norvegicus
OX=10116 GN=Epha7 PE=1 SV=1
Length=998
Score = 51.2 bits (121), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 58/220 (26%), Positives = 91/220 (41%), Gaps = 27/220 (12%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW-----DGGRETHLETNFTLKSEWATHKFADCKAK---R 176
PP P+NL +N+ + EW +GGR + W + C +
Sbjct 331 PPSAPQNLIFNINQ-TTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYM 389
Query 177 DTPTSCTVDYSTVY----FVNIEVWVEAENALGKVTSDHINFDPVYKV--KPNPPHNLSV 230
T +Y TV N VEA N + ++ F V + P V
Sbjct 390 PQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGV 449
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS--TWSQIPPEDTASTRSSFTVQD 288
+ L ++L+W P + +I +Y I+Y KD T+S + + T+++ + +
Sbjct 450 MKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTLKTKSTSAS-----INN 504
Query 289 LKPFTEYVFRIRCMKEDGKGYWS---DWS--EEASGITYE 323
LKP T YVF+IR G G +S D + EEASG +E
Sbjct 505 LKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEASGKMFE 544
>sp|F1NWE3|PTPRS_CHICK Receptor-type tyrosine-protein phosphatase
S OS=Gallus gallus OX=9031 GN=PTPRS PE=1 SV=3
Length=1516
Score = 51.2 bits (121), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 54/164 (33%), Positives = 81/164 (49%), Gaps = 17/164 (10%)
Query 448 ESVKKYILEWCVLSDKAPCITDWQ-QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ V Y++E+ S P +Q +ED T R Y G L+ + Y I V+ V + G G
Sbjct 348 DPVSYYVIEYKSKSQDGP----YQIKEDITTTR-YSIGGLSPNSEYEIWVSAVNSIGQGP 402
Query 507 P-ESIKAYL-KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT---- 560
P ES+ +QAP S V+ + + +++W++ PV+ NG IR Y ++Y
Sbjct 403 PSESVVTRTGEQAPASAPRNVQGRMLSSTTMIIQWEE-PVE-PNGQIRGYRVYYTMEPDQ 460
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
+ N NVD S T+ SL D Y VR+ A+T G DGP
Sbjct 461 PVSNWQKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVG--DGP 501
Score = 41.6 bits (96), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 8/90 (9%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P P N E S +L +W+ P + II+KY + ++ D ++P +T
Sbjct 515 PGQPMNFRAEAKTETSIVL--SWSPP--RQEIIVKYELLFKEGDHG--REVPRNFEPTT- 567
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
SFTV+ LKP TEYVFR+ G G ++
Sbjct 568 -SFTVEGLKPNTEYVFRLAARSALGLGAFT 596
>sp|P97527|CNTN5_RAT Contactin-5 OS=Rattus norvegicus OX=10116
GN=Cntn5 PE=1 SV=1
Length=1099
Score = 50.8 bits (120), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 106/443 (24%), Positives = 175/443 (40%), Gaps = 55/443 (12%)
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELS-SILKLTWTNPSIKSVIILKYNIQYRTK 264
+ T+D ++ + V+ PP V+ EE++ S L+W+ + I YN+Q R+
Sbjct 653 QTTADSVSDEAELLVR-GPPGPPGVVIVEEITESTATLSWSPATDNHSPISSYNLQARSP 711
Query 265 DASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI-T 321
+ W + PE S DL P+ EY FR+ G G D S + I T
Sbjct 712 FSLGWQTVKTVPEVITGDMESAMAVDLNPWVEYEFRVVATNPIGTG---DPSIPSRMIRT 768
Query 322 YEDRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTL----TR-WKS 375
E P APS + S G R + + W+ + NG+ Y V TR WK
Sbjct 769 NEAVPKTAPS-----NVSGGSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKE 823
Query 376 HLQNYTVNATKLTVNLTNDRYLATLT-------VRNLVGKSD-AAVLTIPACDFQATHPV 427
+ V ++ + + D + LT V N G + ++ I + + + T
Sbjct 824 KM----VTSSDASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPTAAP 879
Query 428 MDLKAFPKD-NMLWVEWTTPRESVKK-YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
D+ A + ++V W +ES+ + E D P ++ RT RGN
Sbjct 880 TDVTATSVSVSEIFVVWKHVKESLGRPQGFEIGYWKDTEP------EDSAETVRT--RGN 931
Query 486 --------LAESKCYLITVTPVYADGPGSP-ESIKAYLKQAPPSKGP-TVRTKKVGKNEA 535
L Y +TV G G P + A K+ PPS+ P +R ++ G ++
Sbjct 932 ESFVMLTGLEGDTLYHLTVRAYNGAGYGPPSREVSATTKRHPPSEPPGNLRWEQQG-SQV 990
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
L W+ + + Y +FYR + V + + L +Y++ + AY
Sbjct 991 SLGWEPVRPLANESEVMGYKVFYRQ--EGHSKGQVIETQKPQAVVPLPEAGVYIIEVRAY 1048
Query 596 TDEGGKDGPEFTFTTPKFAQGEI 618
+ EGG P +A G+I
Sbjct 1049 S-EGGDGTASSQIRVPSYAGGKI 1070
>sp|G5EF96|UNC40_CAEEL Netrin receptor unc-40 OS=Caenorhabditis
elegans OX=6239 GN=unc-40 PE=1 SV=1
Length=1415
Score = 50.8 bits (120), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 46/182 (25%), Positives = 85/182 (47%), Gaps = 15/182 (8%)
Query 191 FVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+ ++ +EAE + G ++SD + PP N+ + S+ ++++W P
Sbjct 601 YTGYQIRIEAEGSNGSGLSSDTVKVRTQSDEPSAPPVNIQA--EADSSTSVRVSWDEPEE 658
Query 250 KSVI--ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
+SV I Y ++Y+TK D +T +T+ +L+P T+Y+ R+ + +G
Sbjct 659 ESVNGEITGYRLKYKTKARGAKGNTLVID--ATAREYTMGNLEPNTQYLIRMAVVNHNGT 716
Query 308 GYWSDW-SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
G +SDW S + G E+R AP +I P G + + W LPP + + Y
Sbjct 717 GPFSDWVSIDTPGQDKEERTLGAPR---EIRPH--AGIDYILVSW--LPPADEQNLVRGY 769
Query 367 EV 368
++
Sbjct 770 QI 771
Score = 42.7 bits (99), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 50/187 (27%), Positives = 87/187 (47%), Gaps = 21/187 (11%)
Query 231 INSEELSSI-LKLTWTNPSIKSVIILKYNIQYRTK-DASTWSQIPPEDTASTRSSFTVQD 288
+ +E +S+ +++ WT S ++ +Y ++Y T D + + ST + TV+
Sbjct 855 VRAEAISATSIRVMWTE-SDETAFNTQYTVRYSTAVDGNQHRYV-----NSTETWATVEG 908
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
L+P TEY F +R + +G+ S WS T PS AP + P+ + +
Sbjct 909 LRPATEYEFAVRAVASNGQ--LSTWSMATRNRTLAAPPSSAPRD-LTVLPAESGDPHSSS 965
Query 349 LVWKTLPPFEANGKILDYEVTLT-RWKSHLQNYTVN---ATKLTVNLTN----DRYLATL 400
L W+ PP +NG+I +Y V T R +++T+N KL+ ++N Y +
Sbjct 966 LHWQ--PPKYSNGEIEEYLVFYTDRASLADKDWTINYVAGDKLSHQVSNLLPKANYFFKI 1023
Query 401 TVRNLVG 407
RN G
Sbjct 1024 QARNEKG 1030
Score = 37.4 bits (85), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 88/401 (22%), Positives = 155/401 (39%), Gaps = 59/401 (15%)
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
L + ++ S + + W P ++ I++Y+I Y+ I S+ +S T+
Sbjct 444 LGLRSTSSGSRFINVEWDPPVQRNGNIMRYHIFYKDNLIDRERMI-----NSSSTSATLT 498
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV 347
L+P T Y+ R+ E G G +SD S + + + P K S + G T+
Sbjct 499 SLQPSTMYLIRVTAENEAGMGKFSD-SLKVTTNKEQAVPGKVASL-----TTTATGPETI 552
Query 348 QLVWK---------------TLPPFEANGKILDYEVTLTRWKSH-LQNYTVNATKLTVNL 391
+ W + P E N K + T + H + YT ++
Sbjct 553 DIRWSPPSGGQPALRYKIFYSHDPLEKNEKETLITTSTTHYTLHGMDKYTGYQIRIEAEG 612
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES-- 449
+N L++ TV+ + +SD + P + QA + V W P E
Sbjct 613 SNGSGLSSDTVK-VRTQSDEP--SAPPVNIQA--------EADSSTSVRVSWDEPEEESV 661
Query 450 ---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ Y L++ + A T D T R Y GNL + YLI + V +G G
Sbjct 662 NGEITGYRLKYKTKARGAKGNT--LVIDATA-REYTMGNLEPNTQYLIRMAVVNHNGTGP 718
Query 507 PESIKAYLKQAPPSKGPTVRT--------KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
++ P + RT G + ++ W P D QN +R Y I +
Sbjct 719 ---FSDWVSIDTPGQDKEERTLGAPREIRPHAGIDYILVSW-LPPADEQN-LVRGYQIGW 773
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ + + V +S T+Y ++ L S+ Y++ + A+ + G
Sbjct 774 GLSVPDTETIRVTASTTQYKIARLHSERDYVISLRAFNNLG 814
>sp|Q8VHZ8|DSCAM_RAT Cell adhesion molecule DSCAM OS=Rattus norvegicus
OX=10116 GN=Dscam PE=1 SV=1
Length=2013
Score = 50.8 bits (120), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 94/401 (23%), Positives = 159/401 (40%), Gaps = 50/401 (12%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L WT + I Y+I+ + K S S +D + +S T+ D+ P + Y R+
Sbjct 901 ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRM 960
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
GK S+ S E + IT ++ P ++P+ +Q ++++ WK
Sbjct 961 YAKNRIGK---SEPSNEIT-ITADEAAPDGPPQEVHLEPTSSQ---SIRVTWKAPKKHLQ 1013
Query 360 NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
NG I Y++ + + N+ N ++++ T D + TL N K L + AC
Sbjct 1014 NGIIRGYQIGYREYSTG-GNFQFNI--ISIDTTGDSEVYTLDNLN---KFTQYGLVVQAC 1067
Query 420 DFQATHP---------VMDLKAFPKDNM---------LWVEWTTPRESVKKYILE----- 456
+ T P + D+ ++P +N+ + + W+T + IL+
Sbjct 1068 NRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVI 1127
Query 457 -WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-SPESIKAYL 514
W L D + + + T L G L + Y I V G G E I
Sbjct 1128 YWANLIDGE--LGEIKNVTTTQPSLELDG-LEKYTNYSIQVLAFTRAGDGVRSEQIFTRT 1184
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF----YRTIIGNETAVNV 570
K+ P V+ + + W LP NG IR YT+F Y T+I +E +
Sbjct 1185 KEDVPGPPAGVKAAAASASMVFVSW--LPPLKLNGIIRKYTVFCSHPYPTVI-SEFEASP 1241
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP 611
DS Y + +L+ + Y V + A T G + E P
Sbjct 1242 DS--FSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEP 1280
Score = 36.2 bits (82), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 61/289 (21%), Positives = 112/289 (39%), Gaps = 23/289 (8%)
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTR----WKSHLQNYTVNATKLTVNLTNDRYLATL 400
RT+ L W F+ N I Y++ W S + V+ + + + +T
Sbjct 899 RTITLRWTM--GFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTY 956
Query 401 TVR----NLVGKSDAA-VLTIPACDFQATHPVMDLKAFPKDNM-LWVEWTTPRESVKKYI 454
++R N +GKS+ + +TI A + P ++ P + + V W P++ ++ I
Sbjct 957 SIRMYAKNRIGKSEPSNEITITADEAAPDGPPQEVHLEPTSSQSIRVTWKAPKKHLQNGI 1016
Query 455 LE-WCVLSDKAPCITDWQQEDGTVHRT-----YLRGNLAESKCYLITVTPV--YADGPGS 506
+ + + + ++Q ++ T Y NL + Y + V GP S
Sbjct 1017 IRGYQIGYREYSTGGNFQFNIISIDTTGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSS 1076
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY-TIFYRTIIGNE 565
E I L+ P V+ + W L + NG ++ + I++ +I E
Sbjct 1077 QEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLIDGE 1136
Query 566 TA--VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
NV ++ L L T Y +++ A+T G E FT K
Sbjct 1137 LGEIKNVTTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTK 1185
>sp|Q9ERC8|DSCAM_MOUSE Cell adhesion molecule DSCAM OS=Mus musculus
OX=10090 GN=Dscam PE=1 SV=1
Length=2013
Score = 50.8 bits (120), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 94/401 (23%), Positives = 159/401 (40%), Gaps = 50/401 (12%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L WT + I Y+I+ + K S S +D + +S T+ D+ P + Y R+
Sbjct 901 ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRM 960
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
GK S+ S E + IT ++ P ++P+ +Q ++++ WK
Sbjct 961 YAKNRIGK---SEPSNEIT-ITADEAAPDGPPQEVHLEPTSSQ---SIRVTWKAPKKHLQ 1013
Query 360 NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
NG I Y++ + + N+ N ++++ T D + TL N K L + AC
Sbjct 1014 NGIIRGYQIGYREYSTG-GNFQFNI--ISIDTTGDSEVYTLDNLN---KFTQYGLVVQAC 1067
Query 420 DFQATHP---------VMDLKAFPKDNM---------LWVEWTTPRESVKKYILE----- 456
+ T P + D+ ++P +N+ + + W+T + IL+
Sbjct 1068 NRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVI 1127
Query 457 -WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-SPESIKAYL 514
W L D + + + T L G L + Y I V G G E I
Sbjct 1128 YWANLIDGE--LGEIKNVTTTQPSLELDG-LEKYTNYSIQVLAFTRAGDGVRSEQIFTRT 1184
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF----YRTIIGNETAVNV 570
K+ P V+ + + W LP NG IR YT+F Y T+I +E +
Sbjct 1185 KEDVPGPPAGVKAAAASASMVFVSW--LPPLKLNGIIRKYTVFCSHPYPTVI-SEFEASP 1241
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP 611
DS Y + +L+ + Y V + A T G + E P
Sbjct 1242 DS--FSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEP 1280
Score = 36.2 bits (82), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 61/289 (21%), Positives = 112/289 (39%), Gaps = 23/289 (8%)
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTR----WKSHLQNYTVNATKLTVNLTNDRYLATL 400
RT+ L W F+ N I Y++ W S + V+ + + + +T
Sbjct 899 RTITLRWTM--GFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTY 956
Query 401 TVR----NLVGKSDAA-VLTIPACDFQATHPVMDLKAFPKDNM-LWVEWTTPRESVKKYI 454
++R N +GKS+ + +TI A + P ++ P + + V W P++ ++ I
Sbjct 957 SIRMYAKNRIGKSEPSNEITITADEAAPDGPPQEVHLEPTSSQSIRVTWKAPKKHLQNGI 1016
Query 455 LE-WCVLSDKAPCITDWQQEDGTVHRT-----YLRGNLAESKCYLITVTPV--YADGPGS 506
+ + + + ++Q ++ T Y NL + Y + V GP S
Sbjct 1017 IRGYQIGYREYSTGGNFQFNIISIDTTGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSS 1076
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY-TIFYRTIIGNE 565
E I L+ P V+ + W L + NG ++ + I++ +I E
Sbjct 1077 QEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLIDGE 1136
Query 566 TA--VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
NV ++ L L T Y +++ A+T G E FT K
Sbjct 1137 LGEIKNVTTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTK 1185
>sp|O18796|IL6RA_PIG Interleukin-6 receptor subunit alpha OS=Sus
scrofa OX=9823 GN=IL6R PE=2 SV=2
Length=467
Score = 50.1 bits (118), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 56/230 (24%), Positives = 94/230 (41%), Gaps = 30/230 (13%)
Query 118 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKR 176
+ ++ PPE+P+ LSC + CEW + T K+ KF + +
Sbjct 106 VRLLVDAPPEEPQ-LSCFRKSPLSNVGCEW----RPRSPPSPTTKAVLLVRKFQNSPVE- 159
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENAL-----------GKVTSDHINFDPVYKVKPNPP 225
D C F E +N+ G +S F+ ++P+PP
Sbjct 160 DFQEPCQYSLEAQRFFCQLAVPEGDNSFHIVTLCVANSAGSQSSTPQTFEGYGILQPDPP 219
Query 226 HNLSVINSEELSSILKLTWTNP-SIKSVII-LKYNIQYR---TKDASTWSQIPPEDTAST 280
N++V + L +TW +P S S L++ ++YR +K +TW
Sbjct 220 VNITVSAVDRNPRWLSVTWQDPPSWNSYFYRLQFELRYRAERSKTFTTWM------VKEL 273
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY-EDRPSKA 329
+ + D +V ++R +E G G WS+WS+E +GI + E R S A
Sbjct 274 QHHCIIHDAWSGMRHVVQLRAQEEFGHGLWSEWSQEVTGIPWTESRSSPA 323
>sp|Q60ZN5|SDK_CAEBR Protein sidekick homolog OS=Caenorhabditis
briggsae OX=6238 GN=rig-4 PE=3 SV=1
Length=2322
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 105/464 (23%), Positives = 178/464 (38%), Gaps = 64/464 (14%)
Query 191 FVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
F EV V +EN G+ + +D + V P N+ V S+I+K
Sbjct 1226 FTTYEVNVFSENVFGRSLPTDAVKARTYESVPSGSPRNIVVTAEGSKSAIVKWDPVAELS 1285
Query 250 KSVIILKYNIQYRTKDASTWSQ------IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
+ ++ Y ++ + S + +P + T T+ V +L+PFT Y +
Sbjct 1286 TNGDVIGYKLRVVPERESLMADETREIDVPGQSTLMTK----VSNLRPFTSYYVYMSAYT 1341
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
G G + S S T ED P+ SF + V++ W LPP NGKI
Sbjct 1342 IVGNG--PENSTPLSFETLEDVPAPPESF-----QCSQISEQDVRMKW--LPPGSPNGKI 1392
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLT---------NDRYLATLTVRNLVGKSDAAVL 414
+Y ++ WKSH ++ NL N +Y + +N G+S+ AV
Sbjct 1393 TNY--VISYWKSHEPRSMAIDAQVAGNLLMFSAMSLSPNTQYTFAIKAKNSKGESEEAVA 1450
Query 415 TIPACDFQ-----ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCIT- 468
+ + A PV D + + + W ES+ + + E +A ++
Sbjct 1451 EVMTSSVRLPVRNAPAPVRDTTSQHLATEITIRWD---ESLPRKLTEDAESPVRAVQVSY 1507
Query 469 ------DWQQEDGTVHRTYLRG---NLAESKCYLITVTPV--YADGPGSPES-IKAYLKQ 516
+W + + R +L+ + + + + + + SPES L
Sbjct 1508 QKTNEDEWLTLEKKFEYSKRRAVIKHLSPNSMFRFRIRFIGDFLESSWSPESEWMRTLPS 1567
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET----AVNVDS 572
AP ++ +++ +N LEW N Y I YR NET + V
Sbjct 1568 APFAQPISLKATPYERNSVQLEWVVPHKSTWNSDAIGYRIHYREYPSNETWQMEEIAVHD 1627
Query 573 SH---TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKF 613
H E L+ L++ Y++RM + EG +GP F+ P F
Sbjct 1628 PHEDREEKVLAKLSTFRHYIIRMRLFNSEG--EGP---FSAPVF 1666
Score = 37.7 bits (86), Expect = 0.69, Method: Compositional matrix adjust.
Identities = 31/115 (27%), Positives = 49/115 (43%), Gaps = 11/115 (10%)
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSS-FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y I YR D W ++ T + RSS TV DL+PFT Y + G+ +D
Sbjct 1193 YLIVYREVDEDNWKEV---RTPALRSSEHTVTDLRPFTTYEVNVFSENVFGRSLPTD--- 1246
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
TYE PS +P +G ++ + W + NG ++ Y++ +
Sbjct 1247 AVKARTYESVPSGSPRNIVVT----AEGSKSAIVKWDPVAELSTNGDVIGYKLRV 1297
>sp|Q15375|EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo sapiens
OX=9606 GN=EPHA7 PE=1 SV=3
Length=998
Score = 50.4 bits (119), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 57/220 (26%), Positives = 91/220 (41%), Gaps = 27/220 (12%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW-----DGGRETHLETNFTLKSEWATHKFADCKAK---R 176
PP P+NL +N+ + EW +GGR + W + C +
Sbjct 331 PPSAPQNLIFNINQ-TTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYM 389
Query 177 DTPTSCTVDYSTVY----FVNIEVWVEAENALGKVTSDHINFDPVYKV--KPNPPHNLSV 230
T +Y TV N VEA N + ++ F V + P V
Sbjct 390 PQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGV 449
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS--TWSQIPPEDTASTRSSFTVQD 288
+ L ++L+W P + +I +Y I+Y KD T+S + + T+++ + +
Sbjct 450 MKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSAS-----INN 504
Query 289 LKPFTEYVFRIRCMKEDGKGYWS---DWS--EEASGITYE 323
LKP T YVF+IR G G +S D + EEA+G +E
Sbjct 505 LKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFE 544
>sp|P14781|CNTN1_CHICK Contactin-1 OS=Gallus gallus OX=9031 GN=CNTN1
PE=1 SV=1
Length=1010
Score = 50.4 bits (119), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 93/396 (23%), Positives = 150/396 (38%), Gaps = 43/396 (11%)
Query 231 INSEEL-SSILKLTWTNPSIKSVIILKYNIQYRTKDASTW--SQIPPEDTASTRSSFTVQ 287
I EE+ + + LTW+ + I KY IQ +T + W ++ P D S V
Sbjct 601 IRIEEIRDTAVALTWSRGTDNHSPISKYTIQSKTFLSEEWKDAKTEPSDIEGNMESARVI 660
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG---- 343
DL P+ EY FRI G G E S + R AP + PS G
Sbjct 661 DLIPWMEYEFRIIATNTLGTG-------EPSMPSQRIRTEGAPP---NVAPSDVGGGGGS 710
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRW-KSHLQNYTVNATKLTVNLTNDRYLATLT- 401
R + + W L G Y V + + + TV ++ + D + T
Sbjct 711 NRELTITWMPLSREYHYGNNFGYIVAFKPFGEKEWRRVTVTNPEIGRYVHKDESMPPSTQ 770
Query 402 ----VRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD--------NMLWVEWTTPRE- 448
V+ K D ++ A + A ++ P D + + V W E
Sbjct 771 YQVKVKAFNSKGDGP-FSLTAVIYSAQDAPTEV---PTDVSVKVLSSSEISVSWHHVTEK 826
Query 449 SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP- 507
SV+ Y + + DK Q + + T L NL + Y I V+ + G G P
Sbjct 827 SVEGYQIRYWAAHDKEAAAQRVQVSNQE-YSTKLE-NLKPNTRYHIDVSAFNSAGYGPPS 884
Query 508 ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA 567
+I ++APPS+ P + + + ++ WD + + Y + YR +E
Sbjct 885 RTIDIITRKAPPSQRPRIISSVRSGSRYIITWDHVKAMSNESAVEGYKVLYRPDGQHEGK 944
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ HT + SD Y+V + A+++ G DG
Sbjct 945 LFSTGKHT--IEVPVPSDGEYVVEVRAHSE--GGDG 976
>sp|Q63155|DCC_RAT Netrin receptor DCC OS=Rattus norvegicus OX=10116
GN=Dcc PE=1 SV=2
Length=1445
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 42/131 (32%), Positives = 64/131 (49%), Gaps = 14/131 (11%)
Query 240 LKLTWTNPSI----KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
++++W + S+ K+ + Y +++RT +++ ++ EDT S S+T LKP T Y
Sbjct 860 VRVSWADNSVPKNQKTSDVRLYTVRWRTSFSAS-AKYKSEDTTSL--SYTATGLKPNTMY 916
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
F + K S WS A TYE P+ AP I + R V + W+ P
Sbjct 917 EFSVMVTKNRRS---STWSMTAHATTYEAAPTSAPKDLTVI--TREGKPRAVIVSWQ--P 969
Query 356 PFEANGKILDY 366
P EANGKI Y
Sbjct 970 PLEANGKITAY 980
Score = 38.9 bits (89), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 67/294 (23%), Positives = 109/294 (37%), Gaps = 24/294 (8%)
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY--TVNATKLTVNLTNDRYLATLTV 402
R V+L W+ PP EA G I + V +R + + T L + + N + A T
Sbjct 443 RFVRLSWR--PPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTF 500
Query 403 RNLV------GKSDAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRES---VKK 452
R + G+S + + Q PV +L A + + W P + V+
Sbjct 501 RVVAYNEWGPGESSQPIKVATQPELQVPGPVENLHAVSASPTSILITWEPPAYANGPVQG 560
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-SPESIK 511
Y L +S T +Q +Y L + Y + GPG S + I
Sbjct 561 YRLFCTEVS------TGKEQNIEVDGLSYKLEGLKKFTEYTLRFLAYNRYGPGVSTDDIT 614
Query 512 AYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
PS P V + V + W P QNGFI Y I +R +
Sbjct 615 VVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETL 674
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVP 624
+ ++ Y + L + Y +++A T G GP + T + + +++ VP
Sbjct 675 EPNNLWYLFTGLEKGSQYSFQVSAMTVNG--TGPPSNWYTAETPENDLDESQVP 726
Score = 36.2 bits (82), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 76/339 (22%), Positives = 125/339 (37%), Gaps = 45/339 (13%)
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPS---FWYKIDPS 339
TV +LKP Y FR+ E G G E + I +P + P + + S
Sbjct 487 LTVGNLKPEAMYTFRVVAYNEWGPG------ESSQPIKVATQPELQVPGPVENLHAVSAS 540
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQNYTVNATKLTVNLTNDRYLA 398
T ++ + W+ PP ANG + Y + T + QN V+ L+ L +
Sbjct 541 PT----SILITWE--PPAYANGPVQGYRLFCTEVSTGKEQNIEVDG--LSYKLEGLKKFT 592
Query 399 TLTVRNL--------VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV 450
T+R L V D V+T+ D + P + V W P
Sbjct 593 EYTLRFLAYNRYGPGVSTDDITVVTL--SDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGT 650
Query 451 KK-YILEWCVLSDKAPCITDWQQEDGTVHRT---YLRGNLAESKCYLITVTPVYADGPGS 506
+ +I + + K T + E T+ YL L + Y V+ + +G G
Sbjct 651 QNGFITGYKIRHRK----TTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGP 706
Query 507 P------ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
P E+ + L ++ P+ + N ++ W P N +R Y I Y
Sbjct 707 PSNWYTAETPENDLDESQVPDQPSSLHVRPQTNCIIMSWT--PPLNPNIVVRGYIIGYGV 764
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
V VDS Y++ L S + Y++ + A+ + G
Sbjct 765 GSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAG 803
>sp|P70211|DCC_MOUSE Netrin receptor DCC OS=Mus musculus OX=10090
GN=Dcc PE=1 SV=2
Length=1447
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 42/131 (32%), Positives = 64/131 (49%), Gaps = 14/131 (11%)
Query 240 LKLTWTNPSI----KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
++++W + S+ K+ + Y +++RT +++ ++ EDT S S+T LKP T Y
Sbjct 860 VRVSWADNSVPKNQKTSDVRLYTVRWRTSFSAS-AKYKSEDTTSL--SYTATGLKPNTMY 916
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
F + K S WS A TYE P+ AP I + R V + W+ P
Sbjct 917 EFSVMVTKNRRS---STWSMTAHATTYEAAPTSAPKDLTVI--TREGKPRAVIVSWQ--P 969
Query 356 PFEANGKILDY 366
P EANGKI Y
Sbjct 970 PLEANGKITAY 980
Score = 38.1 bits (87), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 66/294 (22%), Positives = 109/294 (37%), Gaps = 24/294 (8%)
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY--TVNATKLTVNLTNDRYLATLTV 402
R V+L W+ PP EA G I + V +R + + T L + + N + A T
Sbjct 443 RFVRLSWR--PPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTF 500
Query 403 RNLV------GKSDAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRES---VKK 452
R + G+S + + Q PV +L A + + W P + V+
Sbjct 501 RVVAYNEWGPGESSQPIKVATQPELQVPGPVENLHAVSTSPTSILITWEPPAYANGPVQG 560
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-SPESIK 511
Y L +S T +Q +Y L + Y + GPG S + I
Sbjct 561 YRLFCTEVS------TGKEQNIEVDGLSYKLEGLKKFTEYTLRFLAYNRYGPGVSTDDIT 614
Query 512 AYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
PS P + + V + W P QNGFI Y I +R +
Sbjct 615 VVTLSDVPSAPPQNISLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETL 674
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVP 624
+ ++ Y + L + Y +++A T G GP + T + + +++ VP
Sbjct 675 EPNNLWYLFTGLEKGSQYSFQVSAMTVNG--TGPPSNWYTAETPENDLDESQVP 726
Score = 36.2 bits (82), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 75/336 (22%), Positives = 123/336 (37%), Gaps = 39/336 (12%)
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSFWYKIDPSHTQ 342
TV +LKP Y FR+ E G G E + I +P + P + T
Sbjct 487 LTVGNLKPEAMYTFRVVAYNEWGPG------ESSQPIKVATQPELQVPGPVENLHAVSTS 540
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQNYTVNATKLTVNLTNDRYLATLT 401
++ + W+ PP ANG + Y + T + QN V+ L+ L + T
Sbjct 541 P-TSILITWE--PPAYANGPVQGYRLFCTEVSTGKEQNIEVDG--LSYKLEGLKKFTEYT 595
Query 402 VRNL--------VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK- 452
+R L V D V+T+ D + P + V W P +
Sbjct 596 LRFLAYNRYGPGVSTDDITVVTL--SDVPSAPPQNISLEVVNSRSIKVSWLPPPSGTQNG 653
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRT---YLRGNLAESKCYLITVTPVYADGPGSP-- 507
+I + + K T + E T+ YL L + Y V+ + +G G P
Sbjct 654 FITGYKIRHRK----TTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSN 709
Query 508 ----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
E+ + L ++ P+ + N ++ W P N +R Y I Y
Sbjct 710 WYTAETPENDLDESQVPDQPSSLHVRPQTNCIIMSWT--PPLNPNIVVRGYIIGYGVGSP 767
Query 564 NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
V VDS Y++ L S + Y++ + A+ + G
Sbjct 768 YAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAG 803
>sp|O42422|EPHA7_CHICK Ephrin type-A receptor 7 OS=Gallus gallus
OX=9031 GN=EPHA7 PE=2 SV=1
Length=993
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 51/203 (25%), Positives = 82/203 (40%), Gaps = 22/203 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW-----DGGRETHLETNFTLKSEWATHKFADCKAK---R 176
PP P+NL +N+ + EW +GGR + W + C +
Sbjct 331 PPSAPQNLIFNINQ-TTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYM 389
Query 177 DTPTSCTVDYSTVY----FVNIEVWVEAENALGKVTSDHINFDPVYKV--KPNPPHNLSV 230
T +Y TV N VEA N + ++ F V + P V
Sbjct 390 PQQTGLVDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGV 449
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS--TWSQIPPEDTASTRSSFTVQD 288
+ L ++L+W P + +I +Y I+Y KD T+S + + T+++ + +
Sbjct 450 MKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSAS-----INN 504
Query 289 LKPFTEYVFRIRCMKEDGKGYWS 311
LKP T YVF+IR G G +S
Sbjct 505 LKPGTVYVFQIRAFTAAGYGNYS 527
>sp|P43146|DCC_HUMAN Netrin receptor DCC OS=Homo sapiens OX=9606
GN=DCC PE=1 SV=2
Length=1447
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 42/131 (32%), Positives = 64/131 (49%), Gaps = 14/131 (11%)
Query 240 LKLTWTNPSI----KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
++++W + S+ K+ + Y +++RT +++ ++ EDT S S+T LKP T Y
Sbjct 860 VRVSWADNSVPKNQKTSEVRLYTVRWRTSFSAS-AKYKSEDTTSL--SYTATGLKPNTMY 916
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
F + K S WS A TYE P+ AP I + R V + W+ P
Sbjct 917 EFSVMVTKNRRS---STWSMTAHATTYEAAPTSAPKDLTVI--TREGKPRAVIVSWQ--P 969
Query 356 PFEANGKILDY 366
P EANGKI Y
Sbjct 970 PLEANGKITAY 980
Score = 38.9 bits (89), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 67/294 (23%), Positives = 110/294 (37%), Gaps = 24/294 (8%)
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY--TVNATKLTVNLTNDRYLATLTV 402
R V+L W+ PP EA G I + V +R + + T L + + N + A T
Sbjct 443 RFVRLSWR--PPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTF 500
Query 403 RNLV------GKSDAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRES---VKK 452
R + G+S + + Q PV +L+A + + W P + V+
Sbjct 501 RVVAYNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQG 560
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-SPESIK 511
Y L +S T +Q +Y L + Y + GPG S + I
Sbjct 561 YRLFCTEVS------TGKEQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDIT 614
Query 512 AYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
PS P V + V + W P QNGFI Y I +R +
Sbjct 615 VVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETL 674
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVP 624
+ ++ Y + L + Y +++A T G GP + T + + +++ VP
Sbjct 675 EPNNLWYLFTGLEKGSQYSFQVSAMTVNG--TGPPSNWYTAETPENDLDESQVP 726
Score = 35.4 bits (80), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 74/336 (22%), Positives = 123/336 (37%), Gaps = 39/336 (12%)
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSFWYKIDPSHTQ 342
TV +LKP Y FR+ E G G E + I +P + P + T
Sbjct 487 LTVGNLKPEAMYTFRVVAYNEWGPG------ESSQPIKVATQPELQVPGPVENLQAVSTS 540
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQNYTVNATKLTVNLTNDRYLATLT 401
++ + W+ PP ANG + Y + T + QN V+ L+ L + +
Sbjct 541 P-TSILITWE--PPAYANGPVQGYRLFCTEVSTGKEQNIEVDG--LSYKLEGLKKFTEYS 595
Query 402 VRNL--------VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK- 452
+R L V D V+T+ D + P + V W P +
Sbjct 596 LRFLAYNRYGPGVSTDDITVVTL--SDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNG 653
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRT---YLRGNLAESKCYLITVTPVYADGPGSP-- 507
+I + + K T + E T+ YL L + Y V+ + +G G P
Sbjct 654 FITGYKIRHRK----TTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSN 709
Query 508 ----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
E+ + L ++ P+ + N ++ W P N +R Y I Y
Sbjct 710 WYTAETPENDLDESQVPDQPSSLHVRPQTNCIIMSWT--PPLNPNIVVRGYIIGYGVGSP 767
Query 564 NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
V VDS Y++ L S + Y++ + A+ + G
Sbjct 768 YAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAG 803
>sp|P78552|I13R1_HUMAN Interleukin-13 receptor subunit alpha-1
OS=Homo sapiens OX=9606 GN=IL13RA1 PE=1 SV=1
Length=427
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 62/222 (28%), Positives = 89/222 (40%), Gaps = 35/222 (16%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEW--ATHKFADCKA--KRDT 178
G P L CI + M+C W GR T +TN+TL W + K C+ +
Sbjct 123 GDPESAVTELQCIWHNLSYMKCSWLPGRNTSPDTNYTLYY-WHRSLEKIHQCENIFREGQ 181
Query 179 PTSCTVDYSTVY---FVNIEVWVEAENALGKVTSDHINFDPV-YKVKPNPPH--NLSVIN 232
C+ D + V F V + ++ GK+ N P+ +VKP+PPH NLS N
Sbjct 182 YFGCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKPS-FNIVPLTSRVKPDPPHIKNLSFHN 240
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS---------QIPP-EDTASTRS 282
+ L + W NP L Y ++ T + + P E S
Sbjct 241 DD-----LYVQWENPQNFISRCLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNVENTS 295
Query 283 SFTVQDLKPFTEYVFRIR------CMKEDGKGYWSDWSEEAS 318
F V + P T RIR C ++D WS+WS+E S
Sbjct 296 CFMVPGVLPDTLNTVRIRVKTNKLCYEDD--KLWSNWSQEMS 335
>sp|O60469|DSCAM_HUMAN Cell adhesion molecule DSCAM OS=Homo sapiens
OX=9606 GN=DSCAM PE=1 SV=2
Length=2012
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 94/401 (23%), Positives = 158/401 (39%), Gaps = 50/401 (12%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L WT + I Y+I+ + K S S +D + +S T+ D+ P + Y R+
Sbjct 901 ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRM 960
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
GK S+ S E + IT ++ P ++P +Q ++++ WK
Sbjct 961 YAKNRIGK---SEPSNELT-ITADEAAPDGPPQEVHLEPISSQ---SIRVTWKAPKKHLQ 1013
Query 360 NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
NG I Y++ + + N+ N ++V+ + D + TL N K L + AC
Sbjct 1014 NGIIRGYQIGYREYSTG-GNFQFNI--ISVDTSGDSEVYTLDNLN---KFTQYGLVVQAC 1067
Query 420 DFQATHP---------VMDLKAFPKDNM---------LWVEWTTPRESVKKYILE----- 456
+ T P + D+ ++P +N+ + + W+T + IL+
Sbjct 1068 NRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVI 1127
Query 457 -WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-SPESIKAYL 514
W L D + + + T L G L + Y I V G G E I
Sbjct 1128 YWANLMDGE--LGEIKNITTTQPSLELDG-LEKYTNYSIQVLAFTRAGDGVRSEQIFTRT 1184
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF----YRTIIGNETAVNV 570
K+ P V+ + + W LP NG IR YT+F Y T+I +E +
Sbjct 1185 KEDVPGPPAGVKAAAASASMVFVSW--LPPLKLNGIIRKYTVFCSHPYPTVI-SEFEASP 1241
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP 611
DS Y + +L+ + Y V + A T G + E P
Sbjct 1242 DS--FSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEP 1280
Score = 34.7 bits (78), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 60/289 (21%), Positives = 110/289 (38%), Gaps = 23/289 (8%)
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTR----WKSHLQNYTVNATKLTVNLTNDRYLATL 400
RT+ L W F+ N I Y++ W S + V+ + + + +T
Sbjct 899 RTITLRWTM--GFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTY 956
Query 401 TVR----NLVGKSDAA-VLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYI 454
++R N +GKS+ + LTI A + P ++ P + V W P++ ++ I
Sbjct 957 SIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGI 1016
Query 455 LE-WCVLSDKAPCITDWQQEDGTV-----HRTYLRGNLAESKCYLITVTPV--YADGPGS 506
+ + + + ++Q +V Y NL + Y + V GP S
Sbjct 1017 IRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSS 1076
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY-TIFYRTIIGNE 565
E I L+ P V+ + W L + NG ++ + I++ ++ E
Sbjct 1077 QEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGE 1136
Query 566 TA--VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
N+ ++ L L T Y +++ A+T G E FT K
Sbjct 1137 LGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTK 1185
>sp|Q8TDY8|IGDC4_HUMAN Immunoglobulin superfamily DCC subclass
member 4 OS=Homo sapiens OX=9606 GN=IGDCC4 PE=1 SV=1
Length=1250
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 45/156 (29%), Positives = 71/156 (46%), Gaps = 19/156 (12%)
Query 216 PVYKVKPNPPHNLSVINSEELSSI-LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
P+ + P PP + +++E SS + L W P +V I+ Y +++ S +
Sbjct 744 PIQRGPPLPPAH---VHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFSPWGLRNASLV-- 798
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS--F 332
S+ + LKPFT+Y F ++ D G + E + T DRPS PS
Sbjct 799 TYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERS---TLPDRPSTPPSDLR 855
Query 333 WYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
+ PS TV+L W PP E NG+I++Y +
Sbjct 856 LSPLTPS------TVRLHW--CPPTEPNGEIVEYLI 883
Score = 42.4 bits (98), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 37/136 (27%), Positives = 62/136 (46%), Gaps = 17/136 (13%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQY---RTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
SS + + W P + S I+ +++ Y R D + DT + V+DL+P T
Sbjct 442 SSAVLVAWERPEMHSEQIIGFSLHYQKARGMDNVEYQFAVNNDT----TELQVRDLEPNT 497
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF-WYKIDPSHTQGYRTVQLVWK 352
+Y F + + G S S A T +D PS AP +PS +++ W
Sbjct 498 DYEFYVVAYSQLGA---SRTSTPALVHTLDDVPSAAPQLSLSSPNPSD------IRVAWL 548
Query 353 TLPPFEANGKILDYEV 368
LPP +NG+++ Y++
Sbjct 549 PLPPSLSNGQVVKYKI 564
Score = 37.0 bits (84), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 24/84 (29%), Positives = 39/84 (46%), Gaps = 5/84 (6%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV---NVDSSHT 575
PS P + ++ + W LP + NG + Y I Y +G E + V + T
Sbjct 527 PSAAPQLSLSSPNPSDIRVAWLPLPPSLSNGQVVKYKIEYG--LGKEDQIFSTEVRGNET 584
Query 576 EYTLSSLTSDTLYMVRMAAYTDEG 599
+ L+SL + +Y VR++A T G
Sbjct 585 QLMLNSLQPNKVYRVRISAGTAAG 608
>sp|Q9UF33|EPHA6_HUMAN Ephrin type-A receptor 6 OS=Homo sapiens
OX=9606 GN=EPHA6 PE=1 SV=3
Length=1036
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 53/209 (25%), Positives = 84/209 (40%), Gaps = 18/209 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAK-RDT 178
PP P+N+ +NE + EW GGR+ + K T + DC R
Sbjct 331 PPSAPRNVVFNINE-TALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFI 389
Query 179 P------TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPV-YKVKPNPPHNLSVI 231
P + + V VN +EA N + +++ F + + P + V+
Sbjct 390 PRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVV 449
Query 232 NSEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ S + + L+W P+ + IL Y I+Y K+ Q+ T S S + LK
Sbjct 450 RKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHE---QLTYSSTRSKAPSVIITGLK 506
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
P T+YVF IR G +S E +G
Sbjct 507 PATKYVFHIRVRTATGYSGYSQKFEFETG 535
>sp|Q9UQ52|CNTN6_HUMAN Contactin-6 OS=Homo sapiens OX=9606 GN=CNTN6
PE=1 SV=1
Length=1028
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 100/456 (22%), Positives = 172/456 (38%), Gaps = 41/456 (9%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSIL-KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
D + + P PP ++ V E++SS +L+W + I + IQ RT + W +
Sbjct 591 DIIVRGPPGPPEDVQV---EDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVA 647
Query 274 --PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
PE + TV L P+ EY FR+ G G S+ SE T P AP
Sbjct 648 TVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLR--TKASVPVVAP- 704
Query 332 FWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTL-----TRWKSHLQNYTVNAT 385
++ G R+ + + W+++P NG+ Y + T W S + +V ++
Sbjct 705 ----VNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTW-SKEKVSSVESS 759
Query 386 KLTVNLTNDRYLATLTVR----NLVGKSDAAVLTIPAC---DFQATHPVMDLKAFPKDNM 438
+ + L+ V+ N G+ + +TI + Q L++F M
Sbjct 760 RFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEM 819
Query 439 --LW--VEWTTPRESVKKY-ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
W + W V Y +L W D + + G V + G L + Y
Sbjct 820 EVSWNAIAWNRNTGRVLGYEVLYWT--DDSKESMIGKIRVSGNVTTKNITG-LKANTIYF 876
Query 494 ITVTP--VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
+V GP SP + K++PPS+ P K+ ++ L W+ + +
Sbjct 877 ASVRAYNTAGTGPSSP-PVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMENESEV 935
Query 552 RNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP 611
Y I YR ++T + ++ + L D L +R + +GG P
Sbjct 936 LGYKILYRQNRQSKTHILETNNTSAELLVPFEEDYLIEIRTVS---DGGDGSSSEEIRIP 992
Query 612 KFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLI 647
K + I L+ ++ + CF + LI
Sbjct 993 KMSSLSSRGIQFLEPSTHFLSIVIVIFHCFAIQPLI 1028
>sp|Q62413|EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus musculus
OX=10090 GN=Epha6 PE=1 SV=2
Length=1035
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 55/220 (25%), Positives = 83/220 (38%), Gaps = 40/220 (18%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAK-RDT 178
PP P+N++ +NE + EW GGR+ + K T + DC R
Sbjct 330 PPSAPRNVAFNINE-TALILEWSPPSDTGGRKDLTYSVICKKCGLDTTQCEDCGGGLRFI 388
Query 179 P------TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
P + V V VN +EA N + +++ + P P ++V
Sbjct 389 PRHTGLINNSVVVLDFVSHVNYTFEIEAMNGVSELS-----------ISPKPFTAITVTT 437
Query 233 SEELSSI-------------LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
+ S+ L L+W P+ + IL Y I+Y K+ Q+ T S
Sbjct 438 DHDAPSLIGMMRKDWASQNSLALSWQAPAFSNGAILDYEIKYYEKEHE---QLTYSSTRS 494
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
S V LKP T Y+F IR G +S E +G
Sbjct 495 KAPSVIVTGLKPATTYIFHIRVRTATGYSGYSQKFEFETG 534
>sp|Q9EQS9|IGDC4_MOUSE Immunoglobulin superfamily DCC subclass
member 4 OS=Mus musculus OX=10090 GN=Igdcc4 PE=2 SV=1
Length=1252
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 47/161 (29%), Positives = 72/161 (45%), Gaps = 29/161 (18%)
Query 216 PVYKVKPNPPHNLSVINSEELSSI-LKLTWTNPSIKSVIILKYNIQY-----RTKDASTW 269
P+ + P PP + +++E SS + L W P +V I+ Y +++ R T+
Sbjct 743 PIQRGPPLPPAH---VHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFGPWGLRNASLVTY 799
Query 270 SQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
ED + LKPFT+Y F ++ D G + E + T DRPS
Sbjct 800 YTSSGED-------ILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERS---TLPDRPSTP 849
Query 330 PS--FWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
PS + PS TV+L W PP E NG+I++Y +
Sbjct 850 PSDLRLSPLTPS------TVRLHW--CPPTEPNGEIVEYLI 882
Score = 40.0 bits (92), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 44/162 (27%), Positives = 72/162 (44%), Gaps = 22/162 (14%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQY---RTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
SS + + W P + S I+ +++ Y R D + DT + V+DL+P T
Sbjct 441 SSSVLVAWERPELHSEQIIGFSLHYQKARGVDNVEYQFAVNNDT----TELQVRDLEPNT 496
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF-WYKIDPSHTQGYRTVQLVWK 352
+Y F + + G S S A T +D PS AP +PS +++ W
Sbjct 497 DYEFYVVAYSQLGA---SRTSSPALVHTLDDVPSAAPQLTLSSPNPSD------IRVAWL 547
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNYTV----NATKLTVN 390
LP +NG++L Y++ K Q ++ N T+LT+N
Sbjct 548 PLPSSLSNGQVLKYKIEYGLGKED-QVFSTEVPGNETQLTLN 588
Score = 39.7 bits (91), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 26/84 (31%), Positives = 40/84 (48%), Gaps = 5/84 (6%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV---NVDSSHT 575
PS P + ++ + W LP + NG + Y I Y +G E V V + T
Sbjct 526 PSAAPQLTLSSPNPSDIRVAWLPLPSSLSNGQVLKYKIEYG--LGKEDQVFSTEVPGNET 583
Query 576 EYTLSSLTSDTLYMVRMAAYTDEG 599
+ TL+SL + +Y VR++A T G
Sbjct 584 QLTLNSLQPNKVYRVRISAGTGAG 607
>sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 OS=Homo sapiens
OX=9606 GN=EPHA5 PE=1 SV=3
Length=1037
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 46/145 (32%), Positives = 63/145 (43%), Gaps = 11/145 (8%)
Query 504 PGSPE--SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI 561
PG+ + S+ QA PS V+ K+ KN L W + D NG I Y I Y
Sbjct 452 PGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQE--PDRPNGIILEYEIKYFEK 509
Query 562 IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTF-TTPKFA----Q 615
+ + S T T L ++Y+ ++ A T G G F F TTP FA Q
Sbjct 510 DQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQ 569
Query 616 GEIEAIVVPVCLA-FLLTTLLGVLF 639
+I I V V + LL ++GVL
Sbjct 570 SQIPVIAVSVTVGVILLAVVIGVLL 594
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 4/72 (6%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L+W P + IIL+Y I+Y KD T I S ++ T + LKP + YVF+I
Sbjct 485 ISLSWQEPDRPNGIILEYEIKYFEKDQETSYTI----IKSKETTITAEGLKPASVYVFQI 540
Query 300 RCMKEDGKGYWS 311
R G G +S
Sbjct 541 RARTAAGYGVFS 552
>sp|P54758|EPHA6_RAT Ephrin type-A receptor 6 OS=Rattus norvegicus
OX=10116 GN=Epha6 PE=2 SV=2
Length=1035
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 54/220 (25%), Positives = 84/220 (38%), Gaps = 40/220 (18%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAK-RDT 178
PP P+N++ +NE + EW GGR+ + K + DC A R
Sbjct 330 PPSAPRNVAFNINE-TALILEWSPPSDTGGRKDLTYSVICKKCGVDASQCEDCGAGLRFI 388
Query 179 P------TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
P + V V VN +EA N + +++ + P P ++V
Sbjct 389 PRPTGLINNSVVVLDFVSHVNYTFEIEAMNGVSELS-----------ISPKPFTAITVTT 437
Query 233 SEELSSI-------------LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
++ S+ L L+W P+ + IL Y I+Y K+ Q+ T S
Sbjct 438 DQDAPSLIGMMRKDWASQNSLALSWQAPAFSNGAILDYEIKYYEKEHE---QLTYSSTRS 494
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
S + LKP T Y+F IR G +S E +G
Sbjct 495 KAPSVIITGLKPATTYIFHIRVRTATGYSGYSQKFEFETG 534
>sp|P0C5E4|PTPRQ_MOUSE Phosphatidylinositol phosphatase PTPRQ
OS=Mus musculus OX=10090 GN=Ptprq PE=1 SV=1
Length=2300
Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 96/427 (22%), Positives = 169/427 (40%), Gaps = 41/427 (10%)
Query 186 YSTVYFVNIEVWVEAENALGK--VTSDHINFDPVYKVKPNPPHNLSVINSEELSSI-LKL 242
Y F W+ A +G +SD I+ VY + P + + E LSS + +
Sbjct 1016 YKLAVFSYYTFWLTASTLVGNGNKSSDVIH---VYTDQDIPEGGVGNLTYESLSSTAINV 1072
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
+WT PS + ++ Y + + + + PP T +S +L+ +T+Y+F+I
Sbjct 1073 SWTPPSQPNGLVFYY-VSLNLQQSPPRHRRPPLTTY--ENSIYFDNLEKYTDYIFKITPS 1129
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
E KG+ ++ + T ED P P I+ ++ L W PP + NG
Sbjct 1130 TE--KGFSETYTAQLHIKTEEDVPDTPP----IINTFKNLSSTSILLSWD--PPLKPNGA 1181
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVN----LTNDRYLATLTVRNLVGKSDAAVLTIPA 418
IL Y +TL ++ + + + + + T +LA R + G +++L
Sbjct 1182 ILSYHLTLQGTHAN-RTFVTSGNHIVLEELSPFTLYSFLA--AARTMKGLGPSSILFFYT 1238
Query 419 CDFQATHPVMDLKAFP-KDNMLWVEWT---TPRESVKKYILEWCVLSDKAPCITDWQQED 474
+ P +L + +W+ W+ P VK Y + + + ++
Sbjct 1239 DESAPLAPPQNLTLINYTSDFVWLTWSPSPLPGGIVKVYSFK---IHEHETDTVFYKNIS 1295
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES--IKAYLKQAPPSKGPTVRTKKVGK 532
G L G L Y I+V+ G G+ S +K +++ P +
Sbjct 1296 GFQTDAKLAG-LEPVSTYSISVSAFTKVGNGNQFSNVVKFTTQESVPDAVQNIACVARDW 1354
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+ WD P NG I +Y I T+ GN T V+ YT + L ++T Y+ +
Sbjct 1355 QSVSVMWD--PPRKANGIIIHYMI---TVEGNSTKVS--PRDPMYTFTKLLANTSYIFEV 1407
Query 593 AAYTDEG 599
A T G
Sbjct 1408 RASTSAG 1414
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 100/431 (23%), Positives = 176/431 (41%), Gaps = 58/431 (13%)
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV--INSEELSSILKLTWT 245
T+Y ++I+ + + G +S ++ V + P N++ I+SEE+ ++ +
Sbjct 728 TLYNISIQSYTRLGH--GNQSSSLLSVRTSETVPDSAPENITYKNISSEEI----EIFFL 781
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P + II KY I + ++ I +T + T+ LK +T YV +
Sbjct 782 PPRSPNGIIQKYTIYLKRSNSHEARTI-----ETTSLTLTIGGLKKYTHYVIEVSASTLK 836
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G+G S S +T ED P P G TV L W+ PP E NG IL
Sbjct 837 GEGV---RSMPISILTEEDAPDSPPQ---NFSVKQLSGV-TVMLSWQ--PPLEPNGIILY 887
Query 366 YEVTLTRW-KSHLQNYTVNATKLTVNLTNDRYLA------TLTVRNLVGKSDAAVLTIPA 418
Y V + W K L+ T+NAT++++ L++ Y A T + R GK+ ++V+
Sbjct 888 YTVYV--WDKVSLK--TINATEVSLELSDLDYHADYSAYVTASTRFGDGKTRSSVINFRT 943
Query 419 CDFQATHPVMDLKAFPKDN----MLWVEWTTPRESVKKYILEWCVLSD---KAPCITDWQ 471
+ + + P D+ + + W P ++ Y + + S + + +
Sbjct 944 PEGEPSDPPKDVHYVNLSSSSIILFWTPPVKPNGIIQYYSVYYQNTSSTFVQNFTLLEVT 1003
Query 472 QEDGTVHRTYLRGNLAESKCYL--ITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKK 529
QE G V + LA Y +T + + +G S + I Y Q P G T +
Sbjct 1004 QEPGNVTVSARIYKLAVFSYYTFWLTASTLVGNGNKSSDVIHVYTDQDIPEGGVGNLTYE 1063
Query 530 VGKNEAV-LEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTS--DT 586
+ A+ + W P NG + Y ++N+ S + LT+ ++
Sbjct 1064 SLSSTAINVSWT--PPSQPNGLVFYY-----------VSLNLQQSPPRHRRPPLTTYENS 1110
Query 587 LYMVRMAAYTD 597
+Y + YTD
Sbjct 1111 IYFDNLEKYTD 1121
Score = 41.6 bits (96), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 35/141 (25%), Positives = 62/141 (44%), Gaps = 7/141 (5%)
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
V++ + +TD E H +Y+ L + I+V+ G G P + ++
Sbjct 513 VVATRNQYMTDIAAE----HLSYVIRRLVPFTEHTISVSAFTVMGEGPPTVLTVRTREQV 568
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
PS + K + + +L WD P + NG I +YTI+ + N A + + +
Sbjct 569 PSSIQIINYKNISSSSILLYWD--PPEYPNGKITHYTIYAMELDTNR-AFQMTTVDNSFL 625
Query 579 LSSLTSDTLYMVRMAAYTDEG 599
++ L T Y +R+AA T G
Sbjct 626 ITGLKKYTRYKMRVAASTHVG 646
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 78/337 (23%), Positives = 132/337 (39%), Gaps = 35/337 (10%)
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
D A+ S+ ++ L PFTE+ + G+G + + T E PS YK
Sbjct 523 DIAAEHLSYVIRRLVPFTEHTISVSAFTVMGEGPPTVLTVR----TREQVPSSIQIINYK 578
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH--LQNYTVNATKLTVNLTN 393
S ++ L W PP NGKI Y + ++ Q TV+ + L L
Sbjct 579 NISS-----SSILLYWD--PPEYPNGKITHYTIYAMELDTNRAFQMTTVDNSFLITGLKK 631
Query 394 -DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD--------NMLWVEWT 444
RY + VG+S + D P + ++ P+D + L + W+
Sbjct 632 YTRYKMRVAASTHVGESSLS----EENDLFVRTPEDEPESSPQDVKVTDVSPSELSLTWS 687
Query 445 TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
P E I+ + V A + + + T + T +L Y I++ G
Sbjct 688 PP-EKPNGIIIAYEVFYQNADAL--FVKNTSTTNITL--SDLKPYTLYNISIQSYTRLGH 742
Query 505 GSPES--IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII 562
G+ S + + P P T K +E + E LP NG I+ YTI+ +
Sbjct 743 GNQSSSLLSVRTSETVPDSAPENITYKNISSEEI-EIFFLPPRSPNGIIQKYTIYLKRSN 801
Query 563 GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+E A ++++ T+ L T Y++ ++A T +G
Sbjct 802 SHE-ARTIETTSLTLTIGGLKKYTHYVIEVSASTLKG 837
>sp|P97798|NEO1_MOUSE Neogenin OS=Mus musculus OX=10090 GN=Neo1
PE=1 SV=2
Length=1492
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 106/499 (21%), Positives = 193/499 (39%), Gaps = 53/499 (11%)
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS 209
+E +L+ +KS+ F C A+ D + + ++ + +L T+
Sbjct 402 KEHNLQVLGLVKSD---EGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSLTSATT 458
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDAST 268
DH+ P P V+ S + +KLTW P S L Y++ Y TK+
Sbjct 459 DHLA---PATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFY-TKEGVA 514
Query 269 WSQIPPEDTAST-RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP- 326
++ E+T+ T+Q+L P T Y+F++ + G G E ++ + E +P
Sbjct 515 RERV--ENTSQPGEMQVTIQNLMPATVYIFKVMAQNKHGSG------ESSAPLRVETQPE 566
Query 327 ----SKAPSF-WYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT-LTRWKSHLQNY 380
AP+ Y P+ ++ + W+T P NG+I +Y++ + + Q+
Sbjct 567 VQLPGPAPNIRAYATSPT------SITVTWET--PLSGNGEIQNYKLYYMEKGTDKEQDI 618
Query 381 TVNATKLTVNLTND------RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP 434
V++ T+N R +A V D AV T+ D + P
Sbjct 619 DVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTL--SDVPSAAPQNLSLEVR 676
Query 435 KDNMLWVEWTTPRESVKK-YILEWCVLSDKAPCITDWQQE--DGTVHRTYLRGNLAESKC 491
+ + W P + + I + + KA +D + GT + G L
Sbjct 677 NSKSIVIHWQPPSSTTQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEG-LDRGTE 735
Query 492 YLITVTPVYADGPG------SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
Y V + +G G S E+ ++ L + + P+ + V+ W P +
Sbjct 736 YNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSW--TPPE 793
Query 546 VQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGP 604
QN +R Y I Y + + VD YT+ +L + Y++ + A+ + G G
Sbjct 794 NQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLY 853
Query 605 EFTFTTPKFAQGEIEAIVV 623
E T P E++ V+
Sbjct 854 ESAVTRPHTDTSEVDLFVI 872
Score = 44.3 bits (103), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 102/437 (23%), Positives = 160/437 (37%), Gaps = 69/437 (16%)
Query 225 PHNLS--VINSEELSSILKLTWTNPS--IKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P NLS V NS+ + + W PS ++ I Y I+YR AS S + T
Sbjct 668 PQNLSLEVRNSKSIV----IHWQPPSSTTQNGQITGYKIRYR--KASRKSDVTETLVTGT 721
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW--SEEASGITYEDRPSKAPSFWYKIDP 338
+ S ++ L TEY FR+ + +G G +DW +E E R + PS + + P
Sbjct 722 QLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLH-VRP 780
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN----D 394
T ++ + W PP N + Y + H Q V+ + + N
Sbjct 781 LVT----SIVVSWT--PPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSS 834
Query 395 RYLATLTVRNLVGKS------------------DAAVLTIPACDFQATHPVM-------D 429
Y+ TL N VG+ D V+ P P+M
Sbjct 835 HYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQAS 894
Query 430 LKAFPKDNMLWVEWTTPRES----VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+ + + W + + P+ + Y + W P T ++ + T +YL
Sbjct 895 ILSHDTIRITWADNSLPKHQKITDSRYYTVRW---KTNIPANTKYKNANATT-LSYLVTG 950
Query 486 LAESKCYLITVTPVYADGPGSPESIKAY-----LKQAPPSKGPTVRTKKVGKNEAVLEWD 540
L + Y +V V S S+ A+ L P K TV +K+ ++ W
Sbjct 951 LKPNTLYEFSVM-VTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQ 1009
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
P NG I Y I+Y T + E V + + + LT DT Y ++ A
Sbjct 1010 --PPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARN 1067
Query 597 DEG-GKDGPEFTFTTPK 612
+G G F TPK
Sbjct 1068 SKGMGPMSEAVQFRTPK 1084
>sp|A5HJM1|IL7RA_CALJA Interleukin-7 receptor subunit alpha OS=Callithrix
jacchus OX=9483 GN=IL7R PE=2 SV=1
Length=459
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 54/99 (55%), Gaps = 8/99 (8%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYR-TKDASTWSQIPPED 276
VKP P +LSVI E + L +T+ + K V +L +++ YR KD + W + +
Sbjct 127 VKPEAPFDLSVIYREGANDFL-VTFNTSHLQKKYVKVLMHDVAYRHEKDENNWMHV---N 182
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKED-GKGYWSDWS 314
+ST+ + + L+P Y ++R + D KG+WS+WS
Sbjct 183 LSSTKLTLLQRKLQPKATYEIKVRSIPGDYFKGFWSEWS 221
>sp|H2A0L7|FND1_PINMG Fibronectin type III domain-containing protein
1 OS=Margaritifera margaritifera OX=102329 PE=1 SV=1
Length=754
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 65/254 (26%), Positives = 102/254 (40%), Gaps = 37/254 (15%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
L P P NL + WD TN+T+ +AT + P +
Sbjct 355 LIPSAPLNLKLEGTKPNAFAVSWDPPTVKGTLTNYTI---YATEESGKATMVTIDPKLTS 411
Query 184 VDYSTVY---FVNIEVWVEAENALG------KVTSDHINFDPVYKVKPNPPHNLSVINSE 234
+Y I + ++N + +VT+D K P P N+ I++
Sbjct 412 YALYNLYEGTMYTIRIAASSDNGMSPKSEPLEVTTD--------KFIPMAPRNVRAIDNN 463
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
L+S+ L W P +I Y I Y T D + + ++ D + T + T+ +L P TE
Sbjct 464 -LTSV-TLEWDAPLPGRGMIRGYRINY-TLDFTDYEEMLISDPSITTA--TITNLTPATE 518
Query 295 YVFRI--RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
Y F++ R MK G G S T D PS+ S ++I G + +Q+ W+
Sbjct 519 YYFQVFARTMKRLGYG-----SHLIMNKTKMDVPSEPMSVVHRI---MDNGLQRIQVSWQ 570
Query 353 TLPPFEANGKILDY 366
PP G I+DY
Sbjct 571 --PPENTYGPIIDY 582
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 49/194 (25%), Positives = 78/194 (40%), Gaps = 24/194 (12%)
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKK-----YILEWCVLSDKAPCITDWQQEDGTVHRT 480
P + K +NM + + +P + K +I C + +TD R+
Sbjct 274 PYFEGKPLTGENMHYKVYFSPSDQYGKATGGEFIFRICDANFTQASVTDLNP------RS 327
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
+ +A + C I + G+ S+K PS ++ + N + WD
Sbjct 328 FYSIQVAATLCEAI-------ESEGTSTSVKT--PDLIPSAPLNLKLEGTKPNAFAVSWD 378
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
P V+ G + NYTI+ G T V +D T Y L +L T+Y +R+AA +D G
Sbjct 379 --PPTVK-GTLTNYTIYATEESGKATMVTIDPKLTSYALYNLYEGTMYTIRIAASSDNGM 435
Query 601 KDGPE-FTFTTPKF 613
E TT KF
Sbjct 436 SPKSEPLEVTTDKF 449
>sp|P13944|COCA1_CHICK Collagen alpha-1(XII) chain OS=Gallus gallus
OX=9031 GN=COL12A1 PE=1 SV=3
Length=3124
Score = 47.4 bits (111), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 88/396 (22%), Positives = 144/396 (36%), Gaps = 56/396 (14%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT---ASTR 281
P NL V N+ S L + W S + + +Y I Y+ + PE + +
Sbjct 1760 PRNLQVYNATSHS--LTVKWDPASGR---VQRYKIIYQPINGDG-----PEQSTMVGGRQ 1809
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+S +Q L+P T Y + M DG+G G T +P DP+ +
Sbjct 1810 NSVVIQKLQPDTPYAITVSSMYADGEG----GRMTGRGRT---KPLTTVKNMLVYDPTTS 1862
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV---NATKLTVNLTNDRYLA 398
T+ + W A G Y+V + T N + +
Sbjct 1863 ----TLNVRWD-----HAEGNPRQYKVFYRPTAGGAEEMTTVPGNTNYVILRSLEPNTPY 1913
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF-PKDNMLWVEWTTPRESVKKYILEW 457
T+TV + + D T + P +++ + P N + V W V++Y + +
Sbjct 1914 TVTVVPVFPEGDGGRTTDTGRTLERGTP-RNIQVYNPTPNSMNVRWEPAPGPVQQYRVNY 1972
Query 458 CVLSDKAP---CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
LS P + D + R L Y I V +YADG G+P +
Sbjct 1973 SPLSGPRPSESIVVPANTRDVMLER------LTPDTAYSINVIALYADGEGNPSQAQG-- 2024
Query 515 KQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN--ETAVNVD 571
+ P GP +R N ++WD +G ++ Y I Y +G+ + V
Sbjct 2025 -RTLPRSGPRNLRVFDETTNSLSVQWDH-----ADGPVQQYRIIYSPTVGDPIDEYTTVP 2078
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
L L SDT Y + + A ++G DG + T
Sbjct 2079 GIRNNVILQPLQSDTPYKITVVAVYEDG--DGGQLT 2112
Score = 38.1 bits (87), Expect = 0.59, Method: Compositional matrix adjust.
Identities = 95/395 (24%), Positives = 151/395 (38%), Gaps = 69/395 (17%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP NL + SE +L W+ P + +Y ++Y PP+ +R
Sbjct 1387 PPSNLVI--SEVTPHSFRLRWSPPPES---VDRYRVEYYPTTGG-----PPKQFYVSRME 1436
Query 284 FT--VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG--ITYEDRPSKAPSFWYKIDPS 339
T ++DL P TEY+ + + ED + SE G ITY P +
Sbjct 1437 TTTVLKDLTPETEYIVNVFSVVED------ESSEPLIGREITY-------PLSSVRNLNV 1483
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYE----VTLTRWKSHLQNYTVNATKLTVNLTNDR 395
+ G ++++ W+ P A G +L YE T K +VN +L + N
Sbjct 1484 YDIGSTSMRVRWE--PVNGATGYLLTYEPVNATVPTTEKEMRVGPSVNEVQLVDLIPNTE 1541
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM----LWVEWTTPRESVK 451
Y TLT L G + + P + T P+ + ++ + V W V+
Sbjct 1542 Y--TLTAYVLYGD----ITSDPLTSQEVTLPLPGPRGVTIRDVTHSTMNVLWDPAPGKVR 1595
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
KYI+ + + +D+A + E + + +L+ + Y + V VY +G P
Sbjct 1596 KYIIRYKI-ADEADV---KEVEIDRLKTSTTLTDLSSQRLYNVKVVAVYDEGESLPVVAS 1651
Query 512 AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-------N 564
Y P +R ++ KN WD DV YR G
Sbjct 1652 CYSAVPSPVN---LRITEITKNSFRGTWDHGAPDVS---------LYRITWGPYGRSEKA 1699
Query 565 ETAVNVDSSHTEYTLSSLTSDTLYMVRMAA-YTDE 598
E+ VN D + + +L DTLY V + A Y DE
Sbjct 1700 ESIVNGDVNSLLF--ENLNPDTLYEVSVTAIYPDE 1732
Score = 37.4 bits (85), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 57/241 (24%), Positives = 82/241 (34%), Gaps = 40/241 (17%)
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
L V+W V++Y + + ++ P + G + + L Y ITV+
Sbjct 1773 LTVKWDPASGRVQRYKIIYQPINGDGP---EQSTMVGGRQNSVVIQKLQPDTPYAITVSS 1829
Query 499 VYADGPGSPESIKAYLKQAPPSKG-----PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
+YADG G + + K K PT T V WD G R
Sbjct 1830 MYADGEGGRMTGRGRTKPLTTVKNMLVYDPTTSTLNV-------RWDH-----AEGNPRQ 1877
Query 554 YTIFYRTIIGNETAVNVDSSHTEYT-LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
Y +FYR G + +T Y L SL +T Y V + EG DG T T
Sbjct 1878 YKVFYRPTAGGAEEMTTVPGNTNYVILRSLEPNTPYTVTVVPVFPEG--DGGRTTDTGRT 1935
Query 613 FAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPP 672
+G I V +N W P P + + +SP + P
Sbjct 1936 LERGTPRNIQV-----------------YNPTPNSMNVRWEPAPGPVQQYRVNYSPLSGP 1978
Query 673 R 673
R
Sbjct 1979 R 1979
Score = 35.8 bits (81), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 33/119 (28%), Positives = 48/119 (40%), Gaps = 13/119 (11%)
Query 485 NLAESKCYLITVTPVYADGPGSP---ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
NL Y ++V Y DG G P E +K AP + +R + ++ W
Sbjct 689 NLLPETTYAVSVIAEYEDGDGPPLDGEETTLEVKGAPRN----LRITDETTDSFIVGWTP 744
Query 542 LPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
P G + Y + YR + G E V V ++ TL +L DT Y V + A G
Sbjct 745 AP-----GNVLRYRLVYRPLTGGERRQVTVSANERSTTLRNLIPDTRYEVSVIAEYQSG 798
>sp|P68500|CNTN5_MOUSE Contactin-5 OS=Mus musculus OX=10090 GN=Cntn5
PE=1 SV=2
Length=1098
Score = 47.0 bits (110), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 102/444 (23%), Positives = 177/444 (40%), Gaps = 57/444 (13%)
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELS-SILKLTWTNPSIKSVIILKYNIQYRTK 264
+ T+D ++ + V+ PP V+ EE++ S L+W+ + I YN+Q R+
Sbjct 652 QTTADSVSDEAELLVR-GPPGPPGVVIVEEITESTATLSWSPATDNHSPISSYNLQARSP 710
Query 265 DASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI-T 321
+ W + PE S DL P+ EY FR+ G G D S + I T
Sbjct 711 FSLGWQTVKTVPEVITGDMESAMAVDLNPWVEYEFRVVATNPIGTG---DPSIPSRMIRT 767
Query 322 YEDRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTL----TR-WKS 375
E P APS + S G R + + W+ + NG+ Y V TR WK
Sbjct 768 NEAVPKTAPS-----NVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKE 822
Query 376 HLQNYTVNATKLTVNLTNDRYLATLT-------VRNLVGKSD-AAVLTIPACDFQATHPV 427
+ V +++ + + D + LT V N G + ++ I + + + T
Sbjct 823 KM----VTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPTAAP 878
Query 428 MDLKAFPKD-NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ--QEDGTVHRTYLRG 484
D+ A + ++V W +ES+ + + I+ W+ + + +V RG
Sbjct 879 TDVTATSVSVSEIFVVWKHVKESLGR---------PQGFEISYWKDTEPEDSVETVRTRG 929
Query 485 N--------LAESKCYLITVTPVYADGPGSP-ESIKAYLKQAPPSKGP-TVRTKKVGKNE 534
N L + Y +TV G G P K+ PP + P +R ++ G ++
Sbjct 930 NESFVMLTGLEGNTLYHLTVRAYNGAGYGPPSREASTTTKRHPPREPPGNLRWEQQG-SQ 988
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
L W+ + + Y +FYR +E V + + L +Y++ + A
Sbjct 989 VSLGWEPVRPLANESEVMGYKVFYRQEGHSEG--QVIETQKPQAVVPLPEAGVYIIEVRA 1046
Query 595 YTDEGGKDGPEFTFTTPKFAQGEI 618
Y+ EGG P ++ G+I
Sbjct 1047 YS-EGGDGTASSQIRVPSYSGGKI 1069
>sp|Q90610|NEO1_CHICK Neogenin (Fragment) OS=Gallus gallus OX=9031
PE=2 SV=1
Length=1443
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 105/498 (21%), Positives = 195/498 (39%), Gaps = 52/498 (10%)
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS 209
+E +L+ +KS+ F C A+ D + + +++ + +L T+
Sbjct 357 KEHNLQVLGLVKSD---EGFYQCIAENDVGNAQAGAQLIILDLDVAIPTLPPTSLTSATN 413
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDAST 268
DH+ P P V+ + + ++LTW P S L Y+I Y TK+
Sbjct 414 DHLA---PATTGPLPTAPRDVVATLVSTRFIRLTWRTPVSDPQGDNLTYSIFY-TKEGIN 469
Query 269 WSQIPPEDTAST-RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
++ E+T+ + +Q+L P T YVFR+ + G G S + A+ + P
Sbjct 470 RERV--ENTSRPGETQVMIQNLMPETVYVFRVVAQNKHGHGESSAPLKVATQPEVQ-LPG 526
Query 328 KAPSF-WYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK 386
AP+ Y P+ +V + W+T P NG+I +Y++ K V+
Sbjct 527 PAPNIRAYAGSPT------SVTVTWET--PLSGNGEIQNYKLYYME-KGQDSEQDVDVAG 577
Query 387 LTVNLTNDRYLATLTVRNL--------VGKSDAAVLTIPACDFQATHPV-MDLKAFPKDN 437
L+ +T + + R + V D V T+ D + P + L+A +
Sbjct 578 LSYTITGLKKYTEYSFRVVAYNKHGPGVSTQDVVVRTL--SDVPSAAPQNLTLEARNSKS 635
Query 438 MLWVEWTTPRES-----VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
++ + W P + Y + + +S K+ D + G L L Y
Sbjct 636 IM-LHWQPPPAGTHSGQITGYKIRYRKVSRKS----DVTESVGGTQLFQLIEGLERGTEY 690
Query 493 LITVTPVYADGPG------SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDV 546
+ + +G G S E+ ++ L ++ + P+ + V+ W P +
Sbjct 691 NFRIAAMTVNGTGPATDWVSAETFESDLDESRVPEVPSSLHVRPLVTSIVVSW--TPPEN 748
Query 547 QNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPE 605
QN +R Y I Y + + VD YT+ +L + Y++ + A+ + G G E
Sbjct 749 QNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYE 808
Query 606 FTFTTPKFAQGEIEAIVV 623
T P E++ V+
Sbjct 809 SAVTRPHSDTSEVDLFVI 826
Score = 43.9 bits (102), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 102/435 (23%), Positives = 158/435 (36%), Gaps = 66/435 (15%)
Query 225 PHNLSVINSEELSSILKLTWTNP--SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P NL+ + + SI+ L W P S I Y I+YR S S + E T+
Sbjct 623 PQNLT-LEARNSKSIM-LHWQPPPAGTHSGQITGYKIRYR--KVSRKSDVT-ESVGGTQL 677
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW--SEEASGITYEDRPSKAPSFWYKIDPSH 340
++ L+ TEY FRI M +G G +DW +E E R + PS + + P
Sbjct 678 FQLIEGLERGTEYNFRIAAMTVNGTGPATDWVSAETFESDLDESRVPEVPSSLH-VRPLV 736
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN----DRY 396
T ++ + W PP N + Y + H Q V+ + + N Y
Sbjct 737 T----SIVVSWT--PPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHY 790
Query 397 LATLTVRNLVGKS------------------DAAVLTIPACDFQATHPVM-------DLK 431
+ TL N VG+ D V+ P P+M +
Sbjct 791 VITLKAFNNVGEGIPLYESAVTRPHSDTSEVDLFVINAPYTPVPDPSPMMPPVGVQASIL 850
Query 432 AFPKDNMLWVEWTTPRES----VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
+ + W + + P+ + Y + W P T ++ + T +YL L
Sbjct 851 SHDTIRITWADNSLPKNQKITDARYYTVRW---KTNIPANTKYKTANATT-LSYLVTGLK 906
Query 488 ESKCYLITVTPVYADGPGSPESIKAY-----LKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
+ Y +V V S S+ A+ L P K TV +K+ ++ W
Sbjct 907 PNTLYEFSVM-VTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPRTIIVNWQ-- 963
Query 543 PVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
P NG I Y I+Y T + E V + + + LT DT Y ++ A +
Sbjct 964 PPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSK 1023
Query 599 G-GKDGPEFTFTTPK 612
G G F TPK
Sbjct 1024 GMGPMSEAVQFRTPK 1038
Score = 33.9 bits (76), Expect = 8.9, Method: Compositional matrix adjust.
Identities = 37/157 (24%), Positives = 66/157 (42%), Gaps = 12/157 (8%)
Query 163 EWATHKFADCKAKRDTPTSCTVDY-------STVYFVNIEVWVEAENALGKVTSDHINFD 215
W T+ A+ K K T + T+ Y +T+Y ++ V ++ +T+ F+
Sbjct 879 RWKTNIPANTKYK--TANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFE 936
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPE 275
V +PP +++V++ E + + W PS + I Y I Y T + E
Sbjct 937 ---LVPTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIE 993
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
R + +Q+L T Y F+I+ G G S+
Sbjct 994 PVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSE 1030
>sp|P52179|MYOM1_HUMAN Myomesin-1 OS=Homo sapiens OX=9606 GN=MYOM1
PE=1 SV=2
Length=1685
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 90/400 (23%), Positives = 148/400 (37%), Gaps = 27/400 (7%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
+P + P PP +LSV +E S + L+W P + + Y ++ W ++
Sbjct 631 EPSEGIVPGPPTDLSV--TEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNT 688
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
E + F + DL Y FR+RC G G S+ +E D P KAP
Sbjct 689 ELPVKS-PRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIP-KAPG--- 743
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN--LT 392
KI PS V ++ E G ++ V + N V ++ T + +T
Sbjct 744 KIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVT 803
Query 393 NDRYLATLTVRNLVGKS----DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE 448
Y+ + N G S D+ + + A P + + L E
Sbjct 804 GQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHE 863
Query 449 SVKKYILEWCVLSDK--APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ + +L K P + Q G + + + E +T P A G
Sbjct 864 ASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEE----LTPPPQKAAPQGK 919
Query 507 PES--IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-- 562
+S +K +APPS + + ++ VL W Q P + I Y + YR +I
Sbjct 920 SKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQ-PDKIGGAEITGYYVNYREVIDG 978
Query 563 --GNETAVNVDS-SHTEYTLSSLTSDTLYMVRMAAYTDEG 599
G NV + S Y +S+L + +Y ++AA G
Sbjct 979 VPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAG 1018
>sp|Q92859|NEO1_HUMAN Neogenin OS=Homo sapiens OX=9606 GN=NEO1
PE=1 SV=2
Length=1461
Score = 46.2 bits (108), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 95/427 (22%), Positives = 167/427 (39%), Gaps = 47/427 (11%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P P V+ S + +KLTW P S L Y++ Y TK+ ++ E+T+
Sbjct 437 PLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFY-TKEGIARERV--ENTSHP 493
Query 281 -RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP-----SKAPSF-W 333
T+Q+L P T Y+FR+ + G G E ++ + E +P AP+
Sbjct 494 GEMQVTIQNLMPATVYIFRVMAQNKHGSG------ESSAPLRVETQPEVQLPGPAPNLRA 547
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT-LTRWKSHLQNYTVNATKLTVNLT 392
Y P+ ++ + W+T P NG+I +Y++ + + Q+ V++ T+N
Sbjct 548 YAASPT------SITVTWET--PVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGL 599
Query 393 ND------RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
R +A V D AV T+ D + P + + W P
Sbjct 600 KKYTEYSFRVVAYNKHGPGVSTPDVAVRTL--SDVPSAAPQNLSLEVRNSKSIMIHWQPP 657
Query 447 RESVKK-YILEWCVLSDKAPCITDWQQE--DGTVHRTYLRGNLAESKCYLITVTPVYADG 503
+ + I + + KA +D + GT + G L Y V + +G
Sbjct 658 APATQNGQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEG-LDRGTEYNFRVAALTING 716
Query 504 PG------SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
G S E+ ++ L + + P+ + V+ W P + QN +R Y I
Sbjct 717 TGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSW--TPPENQNIVVRGYAIG 774
Query 558 YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQG 616
Y + + VD YT+ +L + Y++ + A+ + G G E T P
Sbjct 775 YGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTS 834
Query 617 EIEAIVV 623
E++ V+
Sbjct 835 EVDLFVI 841
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 98/433 (23%), Positives = 158/433 (36%), Gaps = 61/433 (14%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P NLS+ S ++ P+ ++ I Y I+YR AS S + + T+ S
Sbjct 637 PQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYR--KASRKSDVTETLVSGTQLSQ 694
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDW--SEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
++ L TEY FR+ + +G G +DW +E E R + PS + + P T
Sbjct 695 LIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLH-VRPLVT- 752
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN----DRYLA 398
++ + W PP N + Y + H Q V+ + + N Y+
Sbjct 753 ---SIVVSWT--PPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVI 807
Query 399 TLTVRNLVGKS------------------DAAVLTIPACDFQATHPVM-------DLKAF 433
TL N VG+ D V+ P P+M + +
Sbjct 808 TLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSH 867
Query 434 PKDNMLWVEWTTPRES----VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
+ W + + P+ + Y + W P T ++ + T +YL L +
Sbjct 868 DTIRITWADNSLPKHQKITDSRYYTVRW---KTNIPANTKYKNANATT-LSYLVTGLKPN 923
Query 490 KCYLITVTPVYADGPGSPESIKAY-----LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
Y +V V S S+ A+ L P K TV +K+ ++ W P
Sbjct 924 TLYEFSVM-VTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVNWQ--PP 980
Query 545 DVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG- 599
NG I Y I+Y T + E V + + + LT DT Y ++ A +G
Sbjct 981 SEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGM 1040
Query 600 GKDGPEFTFTTPK 612
G F TPK
Sbjct 1041 GPMSEAVQFRTPK 1053
Score = 33.9 bits (76), Expect = 9.4, Method: Compositional matrix adjust.
Identities = 35/155 (23%), Positives = 65/155 (42%), Gaps = 8/155 (5%)
Query 163 EWATHKFADCKAKRDTPTSCT-----VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPV 217
W T+ A+ K K T+ + + +T+Y ++ V ++ +T+ F+
Sbjct 894 RWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFE-- 951
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
V +PP +++V++ E + + W PS + I Y I Y T + E
Sbjct 952 -LVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPV 1010
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
R + +Q+L T Y F+I+ G G S+
Sbjct 1011 VGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSE 1045
>sp|F1NY98|DSCAM_CHICK Cell adhesion molecule DSCAM OS=Gallus
gallus OX=9031 GN=DSCAM PE=1 SV=3
Length=2034
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 100/419 (24%), Positives = 163/419 (39%), Gaps = 53/419 (13%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P+PP + E + + L WT + I Y+I+ + K S S +D +
Sbjct 912 PDPPE---IEIREVRARSIALRWTMGFDGNSPITGYDIECKNKSDSWDSVQRTKDVSPQL 968
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+ T+ DL P + Y R+ GK S+ S E + T E P P +++P +
Sbjct 969 NQATIIDLHPSSTYNIRMYAKNRIGK---SEASNELTITTDEAAPDGPPQD-VQLEPISS 1024
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLT 401
Q ++++ WK NG I Y++ R S N+ N ++++ T D + TL
Sbjct 1025 Q---SIRVTWKAPKKHLQNGIIRGYQIGY-REYSAGGNFQFNI--ISIDTTGDSEVYTL- 1077
Query 402 VRNLVGKSDAAVLTIPACDFQATHP---------VMDLKAFPKDNM---------LWVEW 443
N + K + + AC+ P + D+ + P N+ + + W
Sbjct 1078 --NNLKKFTQYGMVVQACNRAGIGPSSQEIITTTLEDVPSCPPGNVQATATSPETISISW 1135
Query 444 TTPRESVKKYILE------WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
+T + IL+ W L D + + + T L G L + Y I V
Sbjct 1136 STLAKETLNGILQGFRVIYWANLLDGE--LGEIRNVTTTQPSLELDG-LEKYTNYSIQVL 1192
Query 498 PVYADGPG-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
G G E I K+ P GP K + + + LP NG IR YT+
Sbjct 1193 AFTRAGDGVRSEQIFTRTKEDVP--GPPAGVKAAASSASTVFVSWLPPLKLNGIIRKYTV 1250
Query 557 F----YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP 611
F Y T+I +E + DS Y + +L+ + Y V + A T G + E P
Sbjct 1251 FCSHPYPTVI-SEFEASPDS--FSYRIPNLSRNRQYSVWVVAVTAAGRGNSSEIITVEP 1306
Score = 36.2 bits (82), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 62/290 (21%), Positives = 114/290 (39%), Gaps = 25/290 (9%)
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTR----WKSHLQNYTVN-----ATKLTVNLTNDR 395
R++ L W F+ N I Y++ W S + V+ AT + ++ ++
Sbjct 925 RSIALRWTM--GFDGNSPITGYDIECKNKSDSWDSVQRTKDVSPQLNQATIIDLHPSST- 981
Query 396 YLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKY 453
Y + +N +GKS+A+ LTI + P D++ P + V W P++ ++
Sbjct 982 YNIRMYAKNRIGKSEASNELTITTDEAAPDGPPQDVQLEPISSQSIRVTWKAPKKHLQNG 1041
Query 454 ILE-WCVLSDKAPCITDWQQEDGTVHRT-----YLRGNLAESKCYLITVTPV--YADGPG 505
I+ + + + ++Q ++ T Y NL + Y + V GP
Sbjct 1042 IIRGYQIGYREYSAGGNFQFNIISIDTTGDSEVYTLNNLKKFTQYGMVVQACNRAGIGPS 1101
Query 506 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY-TIFYRTIIGN 564
S E I L+ P V+ + W L + NG ++ + I++ ++
Sbjct 1102 SQEIITTTLEDVPSCPPGNVQATATSPETISISWSTLAKETLNGILQGFRVIYWANLLDG 1161
Query 565 ETA--VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
E NV ++ L L T Y +++ A+T G E FT K
Sbjct 1162 ELGEIRNVTTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTK 1211
>sp|Q9VN14|CONT_DROME Contactin OS=Drosophila melanogaster OX=7227
GN=Cont PE=1 SV=2
Length=1390
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 60/223 (27%), Positives = 96/223 (43%), Gaps = 29/223 (13%)
Query 190 YFVNIEVWVEAENALGKVTSDHI----NFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
Y+ EV V+A N++GK I + + + +V P P L+ S+ +TW
Sbjct 1121 YYTEYEVKVQAINSVGKGPESEIAVIHSAEDMPQVAPQKPIALAY-----NSTCFNVTWQ 1175
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA-----STRSSFTVQDLKPFTEYVFRIR 300
+ I I +R K T Q ED+ +TR+ + L+P T Y ++
Sbjct 1176 PIDMSRENIRGKLIGHRLKYWKTTHQ--EEDSVYYLSRTTRNWALIVGLQPDTYYFVKVM 1233
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPS--FWYKIDPSHTQGYRTVQLVWKTLPPFE 358
G+G S+ EE TY P K PS Y I+PS TV++VW+ + P +
Sbjct 1234 AYNAAGEGPESERFEER---TYRKAPQKPPSSVHVYGINPS------TVRVVWRYVSPSQ 1284
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLT 401
+ Y+V + W+S T N T + + + Y+ LT
Sbjct 1285 DEEPVEGYKVRI--WESDQNMITANNTIVPIGQKLESYINNLT 1325
>sp|P32004|L1CAM_HUMAN Neural cell adhesion molecule L1 OS=Homo
sapiens OX=9606 GN=L1CAM PE=1 SV=2
Length=1257
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 49/198 (25%), Positives = 84/198 (42%), Gaps = 25/198 (13%)
Query 438 MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITV 496
+ W++W P+ +Y ++W + P WQ++ V +L N + Y I V
Sbjct 738 LRWMDWNAPQ---VQYRVQWRPQGTRGP----WQEQ--IVSDPFLVVSNTSTFVPYEIKV 788
Query 497 TPVYADGPG-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVL-EWDQLPVDVQNGFIRNY 554
V + G G P+ Y + P P + ++ + AVL +W + + G +R Y
Sbjct 789 QAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGY 848
Query 555 TIFY-----------RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ Y R I ++ V V ++ T LS L + Y + + A+ G
Sbjct 849 NVTYWREGSQRKHSKRHI--HKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPA 906
Query 604 PEFTFTTPKFAQGEIEAI 621
EFTF+TP+ G EA+
Sbjct 907 SEFTFSTPEGVPGHPEAL 924
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 21/138 (15%)
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDAS-----TWSQIPPEDTASTRSSFTVQDLKPF 292
S ++++W+ + I KY+I++ K+ + + ++P T++T L P+
Sbjct 629 SQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK------LSPY 682
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV-- 350
Y FR+ + + G G S SE +T E P K P +D +G T +V
Sbjct 683 VHYTFRVTAINKYGPGEPSPVSETV--VTPEAAPEKNP-----VD-VKGEGNETTNMVIT 734
Query 351 WKTLPPFEANGKILDYEV 368
WK L + N + Y V
Sbjct 735 WKPLRWMDWNAPQVQYRV 752
>sp|P34902|IL2RG_MOUSE Cytokine receptor common subunit gamma
OS=Mus musculus OX=10090 GN=Il2rg PE=1 SV=1
Length=369
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 48/208 (23%), Positives = 83/208 (40%), Gaps = 22/208 (11%)
Query 132 LSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWAT---HKFADCKA---KRDTPTSCTVD 185
+ C V + M C W+ E TN TL + + F +C ++ + C +
Sbjct 60 VQCFVFNIEYMNCTWNSSSEPQ-ATNLTLHYRYKVSDNNTFQECSHYLFSKEITSGCQIQ 118
Query 186 YSTV-YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ + V ++ + +N + V P P NL++ N E S L+L W
Sbjct 119 KEDIQLYQTFVVQLQDPQKPQRRAVQKLNLQNL--VIPRAPENLTLSNLSE--SQLELRW 174
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ IK L+Y +QYR+ +W+++ + F++ + Y FR+R
Sbjct 175 KSRHIKERC-LQYLVQYRSNRDRSWTEL----IVNHEPRFSLPSVDELKRYTFRVRSRYN 229
Query 305 DGKG---YWSDWSEEA--SGITYEDRPS 327
G WS WS+ T E+ PS
Sbjct 230 PICGSSQQWSKWSQPVHWGSHTVEENPS 257
>sp|Q38IC7|IL7RA_MACFA Interleukin-7 receptor subunit alpha OS=Macaca
fascicularis OX=9541 GN=IL7R PE=2 SV=1
Length=459
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 29/98 (30%), Positives = 54/98 (55%), Gaps = 6/98 (6%)
Query 220 VKPNPPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYNIQYRT-KDASTWSQIPPEDT 277
VKP P +LSVI E + ++ ++ K V +L +++ YR KD + W + +
Sbjct 127 VKPEAPFDLSVIYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWMHV---NL 183
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKED-GKGYWSDWS 314
+ST+ + ++L+P Y ++R + + KG+WS+WS
Sbjct 184 SSTKLTLLQRNLQPEAMYEIKVRSIPDHYFKGFWSEWS 221
Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 93/200 (47%), Gaps = 29/200 (15%)
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTL--SSLTSDTLY 588
G N+ V+ ++ + + + + + YR ++V+ S T+ TL +L + +Y
Sbjct 142 GANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWMHVNLSSTKLTLLQRNLQPEAMY 201
Query 589 MVRMAAYTDEGGKD-----GPEFTFTTPKF--AQGEIEAIVVPV-CLAFLLTTLLGVLFC 640
+++ + D K P + F TP+ + GE++ I++ + L+F LL +L C
Sbjct 202 EIKVRSIPDHYFKGFWSEWSPSYYFRTPEINNSPGEMDPILLTISLLSFFSVALLVILAC 261
Query 641 FNKRDLIKKHIWPNVPDPSKS--HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVS---VVE 695
+ IK +WP++PD K+ H+ + PR N N ++ +F D V +
Sbjct 262 VLWKKRIKPIVWPSLPDHKKTLEHLCK-----KPRKNLNVS---FNPESFLDCQIHRVDD 313
Query 696 IEAND------KKPFPEDLK 709
I+A D + FP+ L+
Sbjct 314 IQARDEVEGFLQDTFPQQLE 333
>sp|Q2EY13|PRTGB_DANRE Protogenin B (Fragment) OS=Danio rerio
OX=7955 GN=prtgb PE=2 SV=1
Length=1069
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 49/175 (28%), Positives = 75/175 (43%), Gaps = 21/175 (12%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYN 258
AEN+ G V S + +P+ P N I++E +SS + L W P + ++ Y+
Sbjct 382 AENSQGSVVSTSRLIVVQSENRPSAPRN---IHAETISSSAILLAWERPQYNADKVIAYS 438
Query 259 IQYRTKDA---STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
I Y + + + DT +S V DL+P Y F I G S SE
Sbjct 439 IHYMKSEGLNNEEYQAVIGNDT----TSHIVDDLEPARNYTFYIVAYMAMGA---SRMSE 491
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV-WKTLPPFEANGKILDYEVT 369
+ + T ED P + P S T T LV W+ LPP + G++ Y ++
Sbjct 492 QVTRHTLEDVPLRTPEL------SLTSRSPTDILVSWQPLPPKLSRGRVSAYRLS 540
Score = 39.3 bits (90), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 30/136 (22%), Positives = 57/136 (42%), Gaps = 5/136 (4%)
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRT 527
++Q G +++ +L ++ Y + A G E + + + P + P +
Sbjct 451 EYQAVIGNDTTSHIVDDLEPARNYTFYIVAYMAMGASRMSEQVTRHTLEDVPLRTPELSL 510
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG---NETAVNVDSSH-TEYTLSSLT 583
+ ++ W LP + G + Y + YRT N + V + T+Y L L
Sbjct 511 TSRSPTDILVSWQPLPPKLSRGRVSAYRLSYRTATDEQVNSVELPVSGENGTQYLLQDLQ 570
Query 584 SDTLYMVRMAAYTDEG 599
DT+Y++RM+ T G
Sbjct 571 PDTIYLIRMSVSTRVG 586
>sp|P16871|IL7RA_HUMAN Interleukin-7 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL7R PE=1 SV=3
Length=459
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/98 (29%), Positives = 54/98 (55%), Gaps = 6/98 (6%)
Query 220 VKPNPPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYNIQYRT-KDASTWSQIPPEDT 277
VKP P +LSV+ E + ++ ++ K V +L +++ YR KD + W+ + +
Sbjct 127 VKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHV---NL 183
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKED-GKGYWSDWS 314
+ST+ + + L+P Y ++R + + KG+WS+WS
Sbjct 184 SSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWS 221
Score = 43.5 bits (101), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 42/163 (26%), Positives = 74/163 (45%), Gaps = 27/163 (17%)
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD-----GPEFTFTTPKF--AQGEI 618
T VN+ S+ L +Y +++ + D K P + F TP+ + GE+
Sbjct 179 THVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEINNSSGEM 238
Query 619 EAIVVPV-CLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKS--HIAQWSPHTPPRHN 675
+ I++ + L+F LL +L C + IK +WP++PD K+ H+ + PR N
Sbjct 239 DPILLTISILSFFSVALLVILACVLWKKRIKPIVWPSLPDHKKTLEHLCK-----KPRKN 293
Query 676 FNSKDQMYSDGNFTDVS---VVEIEAND------KKPFPEDLK 709
N ++ +F D V +I+A D + FP+ L+
Sbjct 294 LNVS---FNPESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLE 333
>sp|P97603|NEO1_RAT Neogenin (Fragment) OS=Rattus norvegicus OX=10116
GN=Neo1 PE=1 SV=1
Length=1377
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 94/427 (22%), Positives = 168/427 (39%), Gaps = 47/427 (11%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P P V+ S + +KLTW P S L Y++ Y TK+ ++ E+T+
Sbjct 406 PLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFY-TKEGVARERV--ENTSQP 462
Query 281 -RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP-----SKAPSF-W 333
T+Q+L P T Y+F++ + G G E ++ + E +P AP+
Sbjct 463 GEMQVTIQNLMPATVYIFKVMAQNKHGSG------ESSAPLRVETQPEVQLPGPAPNIRA 516
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT-LTRWKSHLQNYTVNATKLTVNLT 392
Y P+ ++ + W+T P NG+I +Y++ + + Q+ V++ T+N
Sbjct 517 YATSPT------SITVTWET--PLSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGL 568
Query 393 ND------RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
R +A V D AV T+ D + P + + W P
Sbjct 569 KKYTEYSFRVVAYNKHGPGVSTQDVAVRTL--SDVPSAAPQNLSLEVRNSKSIVIHWQPP 626
Query 447 RESVKK-YILEWCVLSDKAPCITDWQQE--DGTVHRTYLRGNLAESKCYLITVTPVYADG 503
+ + I + + KA +D + GT + G L Y V + +G
Sbjct 627 SSATQNGQITGYKIRYRKASRKSDVTETVVTGTQLSQLIEG-LDRGTEYNFRVAALTVNG 685
Query 504 PG------SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
G S E+ ++ L ++ + P+ + V+ W P + QN +R Y I
Sbjct 686 TGPATDWLSAETFESDLDESRVPEVPSSLHVRPLVTSIVVSW--TPPENQNIVVRGYAIG 743
Query 558 YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQG 616
Y + + VD YT+ +L + Y++ + A+ + G G E T P
Sbjct 744 YGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTS 803
Query 617 EIEAIVV 623
E++ V+
Sbjct 804 EVDLFVI 810
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 102/437 (23%), Positives = 160/437 (37%), Gaps = 69/437 (16%)
Query 225 PHNLS--VINSEELSSILKLTWTNPS--IKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P NLS V NS+ + + W PS ++ I Y I+YR AS S + T
Sbjct 606 PQNLSLEVRNSKSIV----IHWQPPSSATQNGQITGYKIRYR--KASRKSDVTETVVTGT 659
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW--SEEASGITYEDRPSKAPSFWYKIDP 338
+ S ++ L TEY FR+ + +G G +DW +E E R + PS + + P
Sbjct 660 QLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDESRVPEVPSSLH-VRP 718
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN----D 394
T ++ + W PP N + Y + H Q V+ + + N
Sbjct 719 LVT----SIVVSWT--PPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSS 772
Query 395 RYLATLTVRNLVGKS------------------DAAVLTIPACDFQATHPVM-------D 429
Y+ TL N VG+ D V+ P P+M
Sbjct 773 HYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQAS 832
Query 430 LKAFPKDNMLWVEWTTPRES----VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+ + + W + + P+ + Y + W P T ++ + T +YL
Sbjct 833 ILSHDTIRITWADNSLPKHQKITDSRYYTVRW---KTNIPANTKYKNANATT-LSYLVTG 888
Query 486 LAESKCYLITVTPVYADGPGSPESIKAY-----LKQAPPSKGPTVRTKKVGKNEAVLEWD 540
L + Y +V V S S+ A+ L P K TV +K+ ++ W
Sbjct 889 LKPNTLYEFSVM-VTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQ 947
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
P NG I Y I+Y T + E V + + + LT DT Y ++ A
Sbjct 948 --PPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARN 1005
Query 597 DEG-GKDGPEFTFTTPK 612
+G G F TPK
Sbjct 1006 SKGMGPMSEAVQFRTPK 1022
Score = 33.9 bits (76), Expect = 10.0, Method: Compositional matrix adjust.
Identities = 87/401 (22%), Positives = 147/401 (37%), Gaps = 67/401 (17%)
Query 117 GITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKR 176
+ +S +P P+NLS V K + W ++ T + +K KA R
Sbjct 594 AVRTLSDVPSAAPQNLSLEVRNSKSIVIHW------QPPSSATQNGQITGYKIRYRKASR 647
Query 177 DTPTSCTV-------------DYSTVYFVNIEVWVEAENALGKVT----SDHINFDPVYK 219
+ + TV D T Y N V N G T ++ D
Sbjct 648 KSDVTETVVTGTQLSQLIEGLDRGTEY--NFRVAALTVNGTGPATDWLSAETFESDLDES 705
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
P P +L V L + + ++WT P +++++ Y I Y S +Q D
Sbjct 706 RVPEVPSSLHV---RPLVTSIVVSWTPPENQNIVVRGYAIGYGI--GSPHAQTIKVDYK- 759
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGY----------WSDWSEE---ASGITYEDRP 326
+ +T+++L P + YV ++ G+G +D SE Y P
Sbjct 760 -QRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVP 818
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVW--KTLPPFEANGKILDYEVTLTRWKSHLQNYT--- 381
P + + T+++ W +LP + KI D RWK+++ T
Sbjct 819 DPTPMMPPVGVQASILSHDTIRITWADNSLPKHQ---KITDSRYYTVRWKTNIPANTKYK 875
Query 382 -VNATKLTVNLTNDR--YLATLTVRNLVGKSDAA-VLTIPACDFQ--ATHPVMDLKAFPK 435
NAT L+ +T + L +V G+ + +T F+ T P D+ K
Sbjct 876 NANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSK 935
Query 436 DN---MLWVEWTTPRES---VKKYILEWCVLSDKAPCITDW 470
+ + V W P E+ + YI+ + +D I DW
Sbjct 936 EGKPRTIIVNWQPPSEANGKITGYIIYYS--TDVNAEIHDW 974
>sp|P97528|CNTN6_RAT Contactin-6 OS=Rattus norvegicus OX=10116
GN=Cntn6 PE=1 SV=1
Length=1028
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 97/459 (21%), Positives = 172/459 (37%), Gaps = 60/459 (13%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSIL-KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
D + + P PP ++ V E +SS +L+W + I + IQ RT + W +
Sbjct 591 DIIVRGPPGPPEDVKV---EHISSTTSQLSWRPGPDNNSPIQIFTIQTRTPFSVGWQAVA 647
Query 274 --PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
PE + TV L P+ EY FR+ G G S SE T P+ AP
Sbjct 648 TVPEILNGQTYNATVIGLSPWVEYEFRVVAGNNIGIGEPSKPSELLR--TKASIPNVAP- 704
Query 332 FWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTL-----TRWKSHLQNYTVNAT 385
++ + G R+ + + W+ +P NG+ Y + T W + V ++
Sbjct 705 ----VNINGGGGSRSELVITWEPIPEELQNGEGFGYIIMFRPVGSTTWMKE-KVALVESS 759
Query 386 KLTVNLTNDRYLATLTVRNLV--GKSDAAVLTIPACDFQATHPVM-----DLKAFPKDNM 438
K + L+ V+ V + + ++ T+ P + +++F +M
Sbjct 760 KFIYRNESIMPLSPFEVKVGVYNNEGEGSLSTVSIVYSGEDEPRLAPRGTSVQSFSASDM 819
Query 439 --LW--VEWTTPRESVKKY-ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
W + W V Y +L W TD +E + + + GN+
Sbjct 820 EVSWNAIAWNRNTGRVLGYEVLYW----------TDNSKES-MIGKIRVSGNVTTKNITG 868
Query 494 ITVTPVY----------ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLP 543
+ +Y GP SP + K++PPS+ P K+ ++ L W+ +
Sbjct 869 LRANTIYFASVRAYNTAGTGPSSP-PVNVTTKKSPPSQPPANIAWKLSNSKLCLNWEHVK 927
Query 544 VDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ Y I YR ++T V ++ + L D L +R + +GG
Sbjct 928 TMENESEVLGYKILYRQNRQSKTHVLETNNTSAELLVPFEEDYLIEIRTVS---DGGDGS 984
Query 604 PEFTFTTPKFAQ-GEIEAIVVPVCLAFLLTTLLGVLFCF 641
PK + + ++ FL T++G +CF
Sbjct 985 SSEEIRIPKMSSLSSVGVQILKPSTQFL--TMVGFFYCF 1021
>sp|Q7TPD3|ROBO2_MOUSE Roundabout homolog 2 OS=Mus musculus OX=10090
GN=Robo2 PE=1 SV=2
Length=1470
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 48/173 (28%), Positives = 75/173 (43%), Gaps = 19/173 (11%)
Query 441 VEWTTPRESVKKYILEWCVLSDKAPCI---TDWQQEDGTV--HRTYLRGNLAESKCYLIT 495
V WT R+ ++I + V+ + + T WQ D V R+ + NL + Y I
Sbjct 658 VTWTVDRQ--PQFIQGYRVMYRQTSGLQASTVWQNLDAKVPTERSAVLVNLKKGVTYEIK 715
Query 496 VTPVYADGPGSPESIKAY--LKQAPPSKGPTVRTKKVGKNEAV---LEWDQLPVDVQNGF 550
V P + + G K ++AP + +V VG + + + WD P D QNG
Sbjct 716 VRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPADHQNGI 775
Query 551 IRNYTIFYRTIIGNETAVN----VDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
I+ Y I+ +GNET + VD++ + L Y V +AA T G
Sbjct 776 IQEYKIW---CLGNETRFHINKTVDAAIRSVVIGGLFPGIQYRVEVAASTSAG 825
>sp|O88488|PTPRQ_RAT Phosphatidylinositol phosphatase PTPRQ OS=Rattus
norvegicus OX=10116 GN=Ptprq PE=1 SV=1
Length=2302
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 91/425 (21%), Positives = 165/425 (39%), Gaps = 37/425 (9%)
Query 186 YSTVYFVNIEVWVEAENALGK--VTSDHINFDPVYKVKPNPPHNLSVINSEELSSI-LKL 242
Y F W+ A ++G +SD I+ + P NL+ E +SS + +
Sbjct 1018 YRLAIFSYYTFWLTASTSVGNGNKSSDIIHVYTDQDIPEGPVGNLTF---ESISSTAIHV 1074
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
+W PS + ++ Y + + + IPP + +S DL+ +T+Y+F+I
Sbjct 1075 SWEPPSQPNGLVFYY-LSLNLQQSPPRHMIPP--LVTYENSIDFDDLEKYTDYIFKITPS 1131
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
E KG+ ++ + T ED P P I+ ++ L W PP + NG
Sbjct 1132 TE--KGFSETYTTQLHIKTEEDVPDTPP----IINTFKNLSSTSILLSWD--PPLKPNGA 1183
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL--TVRNLVGKSDAAVLTIPACD 420
IL Y +TL ++ + + + + + L + R + G +++L +
Sbjct 1184 ILGYHLTLQGPHAN-HTFVTSGNHIVLEELSPFTLYSFFAAARTMKGLGPSSILFFYTDE 1242
Query 421 FQATHPVMDLKAFP-KDNMLWVEWT---TPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
P +L + +W+ W+ P VK Y + + + ++ G
Sbjct 1243 SAPLAPPQNLTLINYTSDFVWLTWSPSPLPGGIVKVYSFK---IHEHETDTVFYKNISGL 1299
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPES--IKAYLKQAPPSKGPTVRTKKVGKNE 534
L G L Y ++V+ G G+ S ++ +++ P +
Sbjct 1300 QTDAKLEG-LEPVSTYSVSVSAFTKVGNGNQYSNVVEFTTQESVPEAVRNIECVARDWQS 1358
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
+ WD P NG I +Y I T+ GN T V+ YT + L +T Y+ + A
Sbjct 1359 VSVRWD--PPRKTNGIIIHYMI---TVGGNSTKVS--PRDPTYTFTKLLPNTSYVFEVRA 1411
Query 595 YTDEG 599
T G
Sbjct 1412 STSAG 1416
Score = 41.6 bits (96), Expect = 0.040, Method: Compositional matrix adjust.
Identities = 55/192 (29%), Positives = 83/192 (43%), Gaps = 25/192 (13%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P N++ N S +++++ P + II KY I + ++ I +T +
Sbjct 765 PENITYKNIS--SGEIEISFLPPRSPNGIIQKYTIYLKRSNSHEARTI-----NTTSLTQ 817
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGY 344
T+ LK +T YV + G+G S S +T ED P P G
Sbjct 818 TIGGLKKYTHYVIEVSASTLKGEGI---RSRPISILTEEDAPDSPPQ---NFSVKQLSGV 871
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTRW-KSHLQNYTVNATKLTVNLT----NDRYLAT 399
TV L W+ PP E NG IL Y V + W KS L+ +NAT+ ++ L+ N Y A
Sbjct 872 -TVMLSWQ--PPLEPNGIILYYTVYV--WDKSSLR--AINATEASLVLSDLDYNVDYGAC 924
Query 400 LTVRNLVGKSDA 411
+T G +A
Sbjct 925 VTASTRFGDGNA 936
Score = 41.6 bits (96), Expect = 0.041, Method: Compositional matrix adjust.
Identities = 82/387 (21%), Positives = 144/387 (37%), Gaps = 51/387 (13%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
V PP N I ++W P+I + YR + +I T
Sbjct 306 VPEGPPQN--CIMGNVTGKAFSISWDPPTI-----VTGKFSYRVELYGPSGRILDNSTKD 358
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
R +FT L PFT Y + G G S+ S P P + + +
Sbjct 359 LRFAFT--HLTPFTMYDVYVAAETSAGVGPKSNLSVFT--------PPDVPGAVFDLQIA 408
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH--LQNYTVNATKLTVNLTNDRYL 397
+ +++ W+ P + NG I Y V ++ ++ L+N + +++ +
Sbjct 409 EVEATE-IRITWRK--PRQPNGIISQYRVKVSVLETGVVLENTLLTGQDESISNPMSPEI 465
Query 398 ATLTVRNLVGKSDAAV-----LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
L V ++G + + L PA +HP D A + E ++P
Sbjct 466 MNL-VDPMIGFYEGSGEMSSDLHSPASFIYNSHPHNDFPASTRAE----EQSSP------ 514
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
V++ + +TD E +Y+ L + I+V+ G G P +
Sbjct 515 ------VVTTRNQYMTDITAE----QLSYVVRRLVPFTEHTISVSAFTIMGEGPPTVLTV 564
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS 572
++ PS + K + + +L WD P + NG I +YTI Y T + A + +
Sbjct 565 RTREQVPSSIQIINYKNISSSSILLYWD--PPEYPNGKITHYTI-YATELDTNRAFQMTT 621
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ ++ L T Y +R+AA T G
Sbjct 622 VDNSFLITGLKKYTRYKMRVAASTHVG 648
Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 79/338 (23%), Positives = 132/338 (39%), Gaps = 37/338 (11%)
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
D + + S+ V+ L PFTE+ + G+G + + T E PS YK
Sbjct 525 DITAEQLSYVVRRLVPFTEHTISVSAFTIMGEGPPTVLTVR----TREQVPSSIQIINYK 580
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH--LQNYTVNATKLTVNLTN 393
S ++ L W PP NGKI Y + T ++ Q TV+ + L L
Sbjct 581 NISS-----SSILLYWD--PPEYPNGKITHYTIYATELDTNRAFQMTTVDNSFLITGLKK 633
Query 394 -DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD--------NMLWVEWT 444
RY + VG+S + D P + ++ P+D + L ++W+
Sbjct 634 YTRYKMRVAASTHVGESSLS----EENDIFVRTPEDEPESSPQDVQVTGVSPSELRLKWS 689
Query 445 TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
P E I+ + VL A D T + +L Y I++ G
Sbjct 690 PP-EKPNGIIIAYEVLYQNA----DTLFVKNTSTTDIIISDLKPYTLYNISIRSYTRLGH 744
Query 505 GSPES--IKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI 561
G+ S + + P P + K + E +E LP NG I+ YTI+ +
Sbjct 745 GNQSSSLLSVRTSETVPDSAPENITYKNISSGE--IEISFLPPRSPNGIIQKYTIYLKRS 802
Query 562 IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+E A ++++ T+ L T Y++ ++A T +G
Sbjct 803 NSHE-ARTINTTSLTQTIGGLKKYTHYVIEVSASTLKG 839
Score = 34.3 bits (77), Expect = 8.5, Method: Compositional matrix adjust.
Identities = 43/201 (21%), Positives = 77/201 (38%), Gaps = 25/201 (12%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETH-LETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
PE +N+ C+ + + + WD R+T+ + ++ + + K + RD + T
Sbjct 1343 PEAVRNIECVARDWQSVSVRWDPPRKTNGIIIHYMITVGGNSTKV----SPRDPTYTFTK 1398
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+V V A + G+ + + + P+ P N++ N + S+ LTW
Sbjct 1399 LLPNTSYV---FEVRASTSAGEGNESRCDISTLPETVPSAPTNVAFSNVQSTSA--TLTW 1453
Query 245 TNPSIKSVIILKYNI--QYRTKDASTWSQIPPEDTA----------STRSSFTVQDLKPF 292
T P Y I Q R + W PE+ + ++ TV LK F
Sbjct 1454 TKPDTIFGYFQNYKITTQLRAQKCREWE---PEECIEHQKDQYLYEANQTEETVHGLKKF 1510
Query 293 TEYVFRIRCMKEDGKGYWSDW 313
Y F++ G S+W
Sbjct 1511 RWYRFQVAASTNVGYSNASEW 1531
>sp|P16621|LAR_DROME Tyrosine-protein phosphatase Lar OS=Drosophila
melanogaster OX=7227 GN=Lar PE=1 SV=2
Length=2029
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 113/499 (23%), Positives = 182/499 (36%), Gaps = 79/499 (16%)
Query 131 NLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY 190
NLSCI +W G E D + + P + + +
Sbjct 253 NLSCIAVGSPMPHVKWMKGSE-------------------DLTPENEMP----IGRNVLQ 289
Query 191 FVNIEVWVEAEN--ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
+NI+ E+ N + T I+ V KV+ P V SE ++ ++L W+
Sbjct 290 LINIQ---ESANYTCIAASTLGQIDSVSVVKVQSLPTAPTDVQISEVTATSVRLEWSYKG 346
Query 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
+ + Y IQY+ K+A+ Q E + + V+ L P+TEY F + + G+G
Sbjct 347 PED--LQYYVIQYKPKNAN---QAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIGRG 401
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
S A+ T E + AP + T T+ + W+ PP NG++ Y+V
Sbjct 402 ---PPSAPATCTTGETKMESAP----RNVQVRTLSSSTMVITWE--PPETPNGQVTGYKV 452
Query 369 TLT--------RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
T W S + + N+ TV+ + T+ V+ + T
Sbjct 453 YYTTNSNQPEASWNSQMVD---NSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVK 509
Query 421 FQATHPVMDLKAFPKD---NMLWVEWTTP---RESVKKYILEWC-VLSDKAPCITDWQQE 473
Q P D + ++WT P E++ Y L W +++A +
Sbjct 510 AQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYELYWNDTYANQA------HHK 563
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-----PESIKAYLKQAPPSKGPTVRTK 528
+ Y L Y I + G G+ P K Y+ APP + T
Sbjct 564 RISNSEAYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATS 623
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDT 586
+ L W PV+ NG I Y +F+ +G E A + + T L L T
Sbjct 624 STTIS---LSWLPPPVERSNGRIIYYKVFF-VEVGREDDEATTMTLNMTSIVLDELKRWT 679
Query 587 LYMVRMAAYTDEGGKDGPE 605
Y + + A T G DGP
Sbjct 680 EYKIWVLAGTSVG--DGPR 696
Score = 42.0 bits (97), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 35/135 (26%), Positives = 57/135 (42%), Gaps = 8/135 (6%)
Query 486 LAESKCYLITVTPVYADGPG---SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
L Y + V + G G +P +KA +Q PS+ R +G+ L+W +
Sbjct 481 LTPHAIYTVRVQAYTSMGAGPMSTPVQVKA--QQGVPSQPSNFRATDIGETAVTLQWTKP 538
Query 543 PVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GK 601
+N I +Y +++ N+ S+ YTL L DTLY + +AA + G G
Sbjct 539 THSSEN--IVHYELYWNDTYANQAHHKRISNSEAYTLDGLYPDTLYYIWLAARSQRGEGA 596
Query 602 DGPEFTFTTPKFAQG 616
P T ++ G
Sbjct 597 TTPPIPVRTKQYVPG 611
Score = 40.0 bits (92), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 96/446 (22%), Positives = 171/446 (38%), Gaps = 61/446 (14%)
Query 188 TVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
T+Y++ W+ A + G+ T+ I V PP N++ I + S+ + L+W
Sbjct 580 TLYYI----WLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATS--STTISLSWLP 633
Query 247 PSIK--SVIILKYNIQY----RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
P ++ + I+ Y + + R D +T + +S + +LK +TEY +
Sbjct 634 PPVERSNGRIIYYKVFFVEVGREDDEATTMTL-------NMTSIVLDELKRWTEYKIWVL 686
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA- 359
G G S T ED P K P ++ ++ + WK PP E
Sbjct 687 AGTSVGDG---PRSHPIILRTQEDVPGDPQDV--KATPLNST---SIHVSWK--PPLEKD 736
Query 360 -NGKILDYEVTLTRWKSHLQNYT-------------VNATKLTVNLTNDRYLATLTVRNL 405
NG I Y + + + + N T L + +A LT +
Sbjct 737 RNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRKGD 796
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE--WTTPRES---VKKYILEWCVL 460
+S A V+ P P + LK ++ ++ +E W P ++ ++ Y L W V
Sbjct 797 GDRSAAIVVKTPGG--VPVRPTVSLKIMEREPIVSIELEWERPAQTYGELRGYRLRWGV- 853
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPP 519
D+A + G NL Y V G G E++K + + P
Sbjct 854 KDQA---LKEEMLSGPQMTKKRFDNLERGVEYEFRVAGSNHIGIGQ-ETVKIFQTPEGTP 909
Query 520 SKGPTVRTKKVGKNEAV-LEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
P+ T + + + + WD + +NG I Y + + I + + + +
Sbjct 910 GGPPSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRKAV 969
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGP 604
++L +T Y+ R+ AYT +G GP
Sbjct 970 FTNLEENTEYIFRVRAYTKQGA--GP 993
Score = 38.9 bits (89), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 38/152 (25%), Positives = 72/152 (47%), Gaps = 21/152 (14%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTK-DASTWSQIPPEDTAS 279
PP N+++ + +L +TW P+ ++ II +Y++Q+ K D S+ +
Sbjct 911 GPPSNITI--RFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSE---RNMTL 965
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
++ FT +L+ TEY+FR+R + G G +SD I +R + + +
Sbjct 966 RKAVFT--NLEENTEYIFRVRAYTKQGAGPFSD-----KLIVETERDMGRAPMSLQAEAT 1018
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
Q T ++ W+ P + GK+L Y++ T
Sbjct 1019 SEQ---TAEIWWE---PVTSRGKLLGYKIFYT 1044
>sp|Q60629|EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus musculus
OX=10090 GN=Epha5 PE=1 SV=2
Length=876
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 27/72 (38%), Positives = 37/72 (51%), Gaps = 4/72 (6%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L+W P + IIL+Y I+Y KD T I S +S T + LKP + YVF+I
Sbjct 323 ISLSWQEPDRPNGIILEYEIKYFEKDQETSYTI----IKSKETSITAEGLKPASVYVFQI 378
Query 300 RCMKEDGKGYWS 311
R G G +S
Sbjct 379 RARTAAGYGVFS 390
Score = 36.2 bits (82), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 38/129 (29%), Positives = 52/129 (40%), Gaps = 10/129 (8%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
PS V+ K+ KN L W Q P D NG I Y I Y + + S T T
Sbjct 307 PSPVTNVKKGKIAKNSISLSW-QEP-DRPNGIILEYEIKYFEKDQETSYTIIKSKETSIT 364
Query 579 LSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFA------QGEIEAIVVPVCLA-FL 630
L ++Y+ ++ A T G G F F T + Q +I I V V + L
Sbjct 365 AEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVSVAASNDQSQIPIIAVSVTVGVIL 424
Query 631 LTTLLGVLF 639
L ++G L
Sbjct 425 LAVMIGFLL 433
>sp|O97394|SDK_DROME Protein sidekick OS=Drosophila melanogaster
OX=7227 GN=sdk PE=1 SV=2
Length=2224
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 108/487 (22%), Positives = 181/487 (37%), Gaps = 81/487 (17%)
Query 189 VYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
VY V + + N G +++ I ++ P P N+S + ++ ++ W P
Sbjct 1344 VYHVQVLAYTRLGN--GALSTPPIRVQ-TFEDTPGVPSNVSFPDVS--LTMARIIWDVPV 1398
Query 249 IKSVIILKYNIQYRTKDASTWS---QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
+ IL Y + Y ++ + + PP D +F +L P Y F C +
Sbjct 1399 DPNGKILAYQVTYTLNGSAMLNYSREFPPSD-----RTFRATELLPGKYYSFS--CTAQT 1451
Query 306 GKGYWSDWSEEASGITY----EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
G W + A+ + Y +RP +APS +I S Q + Q+ + P +
Sbjct 1452 RLG----WGKIATALVYTTNNRERP-QAPSV-PQISRSQIQAH---QITFSWTPGRDGFA 1502
Query 362 KILDYEVTLT----RWKS-------HLQNYTVNATK------LTVNLTNDRYLATLTVRN 404
+ Y V + RW+ L ++T + + TND + + +
Sbjct 1503 PLRYYTVEMRENEGRWQPLPERVDPSLSSFTAVGLRPYMTYQFRIQATNDLGPSAFSRES 1562
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPR-------ESVKKYILE 456
++ V T+PA V LK P + V+W+ S Y +
Sbjct 1563 VI------VRTLPAAPAVG---VGGLKVVPITTTSVRVQWSALETALWNGDASTGGYRIL 1613
Query 457 WCVLSDKAPCITDWQQED--GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA-Y 513
+ LSD + + D G + + +L + + Y I V P + GPG A Y
Sbjct 1614 YQQLSDFPTALQSTPKTDVHGINENSVVLSDLQQDRNYEIVVLPFNSQGPGPATPPAAVY 1673
Query 514 LKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG--------- 563
+ +A P+ P V + E L W +QNG I Y I+Y
Sbjct 1674 VGEAVPTGEPRAVDAAPISSTEVRLLWKPPKQSMQNGDILGYKIYYLVTYSPQALEPGRK 1733
Query 564 -NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIV 622
E V ++ T ++L L T Y +++ A+ G DGP T K G A
Sbjct 1734 WEEEIEVVSATATSHSLVFLDKFTEYRIQLLAFNPAG--DGPRSAPITVKTLPGVPSA-- 1789
Query 623 VPVCLAF 629
P+ L F
Sbjct 1790 -PLHLRF 1795
Score = 41.6 bits (96), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 89/397 (22%), Positives = 146/397 (37%), Gaps = 62/397 (16%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+K+ W P + I+ Y ++Y+ KD + + + + TV L+ T Y F I
Sbjct 985 VKVLWAPPRASNGILTGYTVRYQVKDRP--DTLKSFNLTADDTELTVNQLQATTHYWFEI 1042
Query 300 RCMKEDGKGYWSDWSEEASGI--TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
W+ SGI T + P + +V + P F
Sbjct 1043 VA-----------WTRVGSGIPKTATIQSGVEPVLPHAPTALALSNIEAFSVVLQFTPGF 1091
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG------KSDA 411
+ N I T+WK Q N T T+ ND TLTV LV + A
Sbjct 1092 DGNSSI-------TKWKVEGQT-ARNMTWFTICEINDPDAETLTVTGLVPFTQYRLRLSA 1143
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD--------- 462
+ + + +AT ++A PK V T S ++ + W L
Sbjct 1144 SNVVGSSKPSEATKDFQTIQARPKHPPFNV--TVRAMSAQQLRVRWIPLQQTEWYGNPRG 1201
Query 463 ---------KAPCITDWQQ-----EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE 508
K P + ED T + +++ +L E Y + + G S E
Sbjct 1202 YNISYKQLVKTPGTIKYVPRSVVIEDHTAN-SHVLDSLEEWTLYEVKMNACNDVG-CSKE 1259
Query 509 SIKAY--LKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE 565
S A ++A PS GP V+ V++W ++P +NG I Y +FY +
Sbjct 1260 SDTAVERTREAVPSYGPLDVQANATSSTTVVVQWGEVPRQHRNGQIDGYKVFYAAADRGQ 1319
Query 566 TAVNV---DSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
++ +++ TL+ L +Y V++ AYT G
Sbjct 1320 QVLHKTIPNNATFTTTLTELKKYVVYHVQVLAYTRLG 1356
Score = 39.7 bits (91), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 45/188 (24%), Positives = 74/188 (39%), Gaps = 36/188 (19%)
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+T Y+ I W + + K + +PV P+ P L++ N E S +L+ T
Sbjct 1035 TTHYWFEIVAWTRVGSGIPKTATIQSGVEPVL---PHAPTALALSNIEAFSVVLQFT--- 1088
Query 247 PSIK-SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P + I K+ ++ +T TW I E + TV L PFT+Y R+
Sbjct 1089 PGFDGNSSITKWKVEGQTARNMTWFTIC-EINDPDAETLTVTGLVPFTQYRLRL------ 1141
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
AS + +PS+A T+ ++T+Q K PPF + +
Sbjct 1142 ----------SASNVVGSSKPSEA-----------TKDFQTIQARPKH-PPFNVTVRAMS 1179
Query 366 YEVTLTRW 373
+ RW
Sbjct 1180 AQQLRVRW 1187
>sp|Q4VA61|DSCL1_MOUSE Cell adhesion molecule DSCAML1 OS=Mus musculus
OX=10090 GN=Dscaml1 PE=1 SV=2
Length=2053
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 95/410 (23%), Positives = 162/410 (40%), Gaps = 45/410 (11%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P+PP L + E + + L WT + II ++I+Y+ K S + + + T
Sbjct 888 PDPPE-LEI--REVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTI 944
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+ + DL P + Y R+ + G+ S+ S+E + I+ E+ P + P +
Sbjct 945 NQANIVDLHPASVYSIRMYSFNKIGR---SEPSKELT-ISTEEAAPDGPPMDVTLQPVTS 1000
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN--YTVNATKLTVN-----LTND 394
Q ++Q+ WK NG I Y++ R S N Y++ K T + L N
Sbjct 1001 Q---SIQVTWKAPKKELQNGVIRGYQIGY-RENSPGSNGQYSIVEMKATGDSEVYTLDNL 1056
Query 395 RYLATLTV------RNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPR 447
+ A V R G S + + D + P +++A ++ + W+ P
Sbjct 1057 KKFAQYGVVVQAFNRAGTGPSSSEINATTLEDV-PSQPPENVRALSITSDVAVISWSEPP 1115
Query 448 ESVKKYILE------WCVLSDKAPCITDW---QQEDGTVHRTYLRGNLAESKCYLITVTP 498
S +L+ W + D +W Q T R LRG + + Y + V
Sbjct 1116 RSTLNGVLKGYRVIFWSLYVDG-----EWGEMQNVTTTRERVELRG-MEKFTNYSVQVLA 1169
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
G G S+ Y++ GP K V + + + LP NG IR YTIF
Sbjct 1170 YTQAGDGVRSSV-LYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFC 1228
Query 559 RTIIGNETAVNVDSSHTE---YTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ + A + + E Y ++ L Y++ +AA T G + E
Sbjct 1229 SSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSE 1278
>sp|E1C8P7|DSCL1_CHICK Cell adhesion molecule DSCAML1 OS=Gallus
gallus OX=9031 GN=DSCAML1 PE=1 SV=2
Length=2042
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 94/404 (23%), Positives = 157/404 (39%), Gaps = 45/404 (11%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P+PP L + E + + L WT + II ++I+Y+ K S + + + T
Sbjct 889 PDPPE-LEI--REVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTI 945
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+ + DL P + Y R+ + G+ S+ S+E + I+ E+ P + P +
Sbjct 946 NQANIVDLHPASVYSIRMYSFNKIGR---SEPSKELT-ISTEEAAPDGPPMDVTLQPMTS 1001
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN--YTVNATKLTVN-----LTND 394
Q ++Q+ WK NG I Y++ R S N Y++ K T + L N
Sbjct 1002 Q---SIQVTWKAPKKELQNGVIRGYQIGY-RENSPGSNGQYSIVEMKATGDSEVYTLDNL 1057
Query 395 RYLATLTV------RNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPR 447
+ A V R G S + + D + P +++A ++ + W+ P
Sbjct 1058 KKFAQYGVVVQAFNRAGTGPSSSEINATTLEDV-PSQPPENVRAISITSDVAVISWSEPP 1116
Query 448 ESVKKYILE------WCVLSDKAPCITDW---QQEDGTVHRTYLRGNLAESKCYLITVTP 498
S +L+ W + D +W Q T R LRG + + Y + V
Sbjct 1117 RSTLNGVLKGYRVIFWSLYMDG-----EWGEMQNITTTRERVELRG-MEKFTNYSVQVLA 1170
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
G G S+ Y++ GP K V + + + LP NG IR YTIF
Sbjct 1171 YTQAGDGVRSSV-LYIQTKEDIPGPPAGIKAVPSSASSVVVSWLPPAKPNGIIRKYTIFC 1229
Query 559 RTIIGNETA---VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ + A Y ++ L YM+ +AA T G
Sbjct 1230 SSPGSGQPAPSEYETSPDQLFYRIAHLNRGQQYMLWVAAVTSAG 1273
>sp|Q80X19|COEA1_MOUSE Collagen alpha-1(XIV) chain OS=Mus musculus
OX=10090 GN=Col14a1 PE=1 SV=2
Length=1797
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 113/493 (23%), Positives = 182/493 (37%), Gaps = 74/493 (15%)
Query 142 MRCEWDG--GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
MR WD G +L L A D K + T ++ S + F N E V
Sbjct 460 MRVRWDAVPGATGYLILYAPLTEGLA----GDEKEMKIGETHTDIELSGL-FPNTEYTVT 514
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
G+ SD + PP NL + N S+ +LTW S K I Y I
Sbjct 515 VYAMFGEEASDPATGQET-TLPLTPPRNLRISNVGSNSA--RLTWDPASGK---ISGYRI 568
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
Y + D + +++ + ++F ++ L P TEY I + E+G+
Sbjct 569 VYTSADGTEINEVEVDPI----TTFPLKGLTPLTEYSIAIFSIYEEGQSL-----PLVGE 619
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL--------DYEVTLT 371
T E+ P++ + +ID T +R + W L E K++ EV L
Sbjct 620 FTTEEVPAQQ---YLEIDEVKTDSFR---VTWHPLSAEEGQHKLMWIPVYGGKTQEVDL- 672
Query 372 RWKSHLQNYTVNA----TKLTVNLTNDRYLATL------TVRNLVGKSDAAVLTIPACDF 421
K +Y + T+ V+L LA L V VG + T
Sbjct 673 --KEEQDSYVIEGLDPGTEYEVSL-----LAVLDDGSESEVVTAVGTTLDDFWTEAPTAI 725
Query 422 QATHPVMDLKAFPKDNM---------LWVEWTTPRESVKKYILEWC-VLSDKAPCITDWQ 471
+ T PV + N+ L V W +V+++ + + D +
Sbjct 726 EPTSPVTSVLQTGIRNLVVDDETATSLRVSWDISDSNVEQFRVTYLKAQGDPMEEVVGTV 785
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
G + L+ L +++ Y +TVTPVY G G S+ A K P S +R +
Sbjct 786 MVPGVQNSLLLKALLPDTE-YKVTVTPVYTVGEGV--SVSAPGKTLPSSGPQNLRVSEEW 842
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYR--TIIGNETAVNVDSSHTEYTLSSLTSDTLYM 589
N + WD +G ++ Y I Y+ ++ G V + +++L S Y
Sbjct 843 YNRVRITWDP-----PSGPVKGYRIVYKPVSVPGQTLETFVGADINTIVMTNLLSGMDYN 897
Query 590 VRMAAYTDEGGKD 602
V++ A G D
Sbjct 898 VKIFASQASGFSD 910
Score = 38.1 bits (87), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 41/164 (25%), Positives = 64/164 (39%), Gaps = 8/164 (5%)
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
V WT V+KY + + P + DG+V T L+ NL S Y I V
Sbjct 370 FMVNWTQSPGKVEKYRVVYYPTRGGKP---EEVVVDGSVSSTVLK-NLMSSTEYQIAVFA 425
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
V A + E ++ + V +N + WD +P G++ Y
Sbjct 426 VSAHT--ASEGLRGAETTLALPMASDLELYDVTENSMRVRWDAVPG--ATGYLILYAPLT 481
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ G+E + + +HT+ LS L +T Y V + A E D
Sbjct 482 EGLAGDEKEMKIGETHTDIELSGLFPNTEYTVTVYAMFGEEASD 525
>sp|Q8TD84|DSCL1_HUMAN Cell adhesion molecule DSCAML1 OS=Homo
sapiens OX=9606 GN=DSCAML1 PE=1 SV=2
Length=2053
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 95/410 (23%), Positives = 162/410 (40%), Gaps = 45/410 (11%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P+PP L + E + + L WT + II ++I+Y+ K S + + + T
Sbjct 888 PDPPE-LEI--REVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISPTI 944
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+ + DL P + Y R+ + G+ S+ S+E + I+ E+ P + P +
Sbjct 945 NQANIVDLHPASVYSIRMYSFNKIGR---SEPSKELT-ISTEEAAPDGPPMDVTLQPVTS 1000
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN--YTVNATKLTVN-----LTND 394
Q ++Q+ WK NG I Y++ R S N Y++ K T + L N
Sbjct 1001 Q---SIQVTWKAPKKELQNGVIRGYQIGY-RENSPGSNGQYSIVEMKATGDSEVYTLDNL 1056
Query 395 RYLATLTV------RNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPR 447
+ A V R G S + + D + P +++A ++ + W+ P
Sbjct 1057 KKFAQYGVVVQAFNRAGTGPSSSEINATTLEDV-PSQPPENVRALSITSDVAVISWSEPP 1115
Query 448 ESVKKYILE------WCVLSDKAPCITDW---QQEDGTVHRTYLRGNLAESKCYLITVTP 498
S +L+ W + D +W Q T R LRG + + Y + V
Sbjct 1116 RSTLNGVLKGYRVIFWSLYVDG-----EWGEMQNITTTRERVELRG-MEKFTNYSVQVLA 1169
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
G G S+ Y++ GP K V + + + LP NG IR YTIF
Sbjct 1170 YTQAGDGVRSSV-LYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFC 1228
Query 559 RTIIGNETAVNVDSSHTE---YTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ + A + + E Y ++ L Y++ +AA T G + E
Sbjct 1229 SSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSE 1278
>sp|Q00993|UFO_MOUSE Tyrosine-protein kinase receptor UFO OS=Mus
musculus OX=10090 GN=Axl PE=1 SV=2
Length=888
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 57/215 (27%), Positives = 85/215 (40%), Gaps = 27/215 (13%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY- 257
EA NA G TS V P PH+L V++ + + L++ WT P + + L +
Sbjct 200 EAHNAKGVTTSRTATI----TVLPQRPHHLHVVSRQ--PTELEVAWT-PGLSGIYPLTHC 252
Query 258 NIQYRTKD--ASTW--SQIPPEDTASTRSS-----FTVQDLKPFTEYVFRIRCMKEDGKG 308
N+Q D W PPED + + S ++ L P T Y RI C G
Sbjct 253 NLQAVLSDDGVGIWLGKSDPPEDPLTLQVSVPPHQLRLEKLLPHTPYHIRISCSSSQGPS 312
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
W+ W T E P P + S + V + W+ P G +L Y +
Sbjct 313 PWTHWLPVE---TTEGVPLGPPE-----NVSAMRNGSQVLVRWQE-PRVPLQGTLLGYRL 363
Query 369 TLTRWKSHLQNYTVNATK-LTVNLTNDRYLATLTV 402
+ + T+ +T+ L DR +A LTV
Sbjct 364 AYRGQDTPEVLMDIGLTREVTLELRGDRPVANLTV 398
>sp|P54755|EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallus gallus
OX=9031 GN=EPHA5 PE=2 SV=1
Length=1013
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 48/154 (31%), Positives = 65/154 (42%), Gaps = 11/154 (7%)
Query 495 TVTPVYADGPGSPE--SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
V V PG+ + S+ QA PS +V+ K+ KN L W Q P D NG I
Sbjct 419 AVNGVSDQNPGARQFVSVNVTTNQAAPSPVSSVKKGKITKNSISLSW-QEP-DRPNGIIL 476
Query 553 NYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTF-TT 610
Y I Y + + S T T L + Y+ ++ A T G G F F T+
Sbjct 477 EYEIKYFEKDQETSYTIIKSKETAITADGLKPGSAYVFQIRARTAAGYGGFSRRFEFETS 536
Query 611 PKFA----QGEIEAIVVPVCLA-FLLTTLLGVLF 639
P A Q +I IVV V + LL ++G L
Sbjct 537 PVLAASSDQSQIPIIVVSVTVGVILLAVVIGFLL 570
Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 4/72 (6%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L+W P + IIL+Y I+Y KD T I S ++ T LKP + YVF+I
Sbjct 461 ISLSWQEPDRPNGIILEYEIKYFEKDQETSYTI----IKSKETAITADGLKPGSAYVFQI 516
Query 300 RCMKEDGKGYWS 311
R G G +S
Sbjct 517 RARTAAGYGGFS 528
>sp|Q99715|COCA1_HUMAN Collagen alpha-1(XII) chain OS=Homo sapiens
OX=9606 GN=COL12A1 PE=1 SV=2
Length=3063
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 43/161 (27%), Positives = 70/161 (43%), Gaps = 9/161 (6%)
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
+ V+W P YIL + + D P + TV+ L +L + Y +TV
Sbjct 1490 MHVQWQ-PVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLT-DLVPNTEYAVTVQA 1547
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
V D P +++ P + ++ + V + + W+ +P G +R Y + Y
Sbjct 1548 VLHDLTSEPVTVREVTLPLP--RPQDLKLRDVTHSTMNVFWEPVP-----GKVRKYIVRY 1600
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+T + V VD S T +L L S TLY V ++A DEG
Sbjct 1601 KTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEG 1641
Score = 39.3 bits (90), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 72/339 (21%), Positives = 127/339 (37%), Gaps = 47/339 (14%)
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
T + + DL P TEY ++ + D + E + P P D +
Sbjct 1526 TVNDMQLTDLVPNTEYAVTVQAV-------LHDLTSEPVTVREVTLPLPRPQDLKLRDVT 1578
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT 399
H+ T+ + W+ +P GK+ Y V + ++ V+ ++ + +L D + T
Sbjct 1579 HS----TMNVFWEPVP-----GKVRKYIVRYKTPEEDVKEVEVDRSETSTSL-KDLFSQT 1628
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPV-----MDLKAFPKDNMLWVEWTTPRESVKKYI 454
L ++ D + P + T PV + + + W V Y
Sbjct 1629 LYTVSVSAVHDEGE-SPPVTAQETTRPVPAPTNLKITEVTSEGFRGT-WDHGASDVSLYR 1686
Query 455 LEWCVL--SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP------GS 506
+ W SDK I + + T + NL + Y +++T +Y D GS
Sbjct 1687 ITWAPFGSSDKMETILNGDEN------TLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR--TIIGN 564
++ QAP S ++ N ++WD +G ++ Y I Y+ T GN
Sbjct 1741 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDP-----ASGRVQKYRITYQPSTGEGN 1795
Query 565 ETAVNVDSSHTEYTLSSLTSDTLYMVRMAA-YTD-EGGK 601
E + L L DT Y + +++ Y D EGG+
Sbjct 1796 EQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGR 1834
Score = 39.3 bits (90), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 92/388 (24%), Positives = 154/388 (40%), Gaps = 50/388 (13%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P NL + SE +++WT PS + +Y ++Y + + +S
Sbjct 1388 PSNLVI--SERTHRSFRVSWTPPSDS---VDRYKVEYYPVSGGKRQEF---YVSRMETST 1439
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF-WYKIDPSHTQG 343
++DLKP TEYV + + ED ++SE G T + P S Y + P+
Sbjct 1440 VLKDLKPETEYVVNVYSVVED------EYSEPLKG-TEKTLPVPVVSLNIYDVGPT---- 1488
Query 344 YRTVQLVWKTLPPFEANGKILDY----EVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT 399
T+ + W+ P A G IL Y + TR K TVN +LT + N Y
Sbjct 1489 --TMHVQWQ--PVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEY--A 1542
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD---NMLWVEWTTPRESVKKYILE 456
+TV+ ++ + +T+ P DLK +D + + V W V+KYI+
Sbjct 1543 VTVQAVLHDLTSEPVTVREVTLPLPRP-QDLKL--RDVTHSTMNVFWEPVPGKVRKYIVR 1599
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ + + + E T + +L Y ++V+ V+ +G P + + +
Sbjct 1600 YKTPEEDVKEVEVDRSETSTSLK-----DLFSQTLYTVSVSAVHDEGESPPVTAQETTRP 1654
Query 517 APPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT 575
P PT ++ +V WD DV R + + ET +N D
Sbjct 1655 VP---APTNLKITEVTSEGFRGTWDHGASDVS--LYRITWAPFGSSDKMETILNGD--EN 1707
Query 576 EYTLSSLTSDTLYMVRMAA-YTDEGGKD 602
+L +T+Y V + A Y DE D
Sbjct 1708 TLVFENLNPNTIYEVSITAIYPDESESD 1735
Score = 36.6 bits (83), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 61/265 (23%), Positives = 104/265 (39%), Gaps = 26/265 (10%)
Query 359 ANGKILDYEVTL--TRWKSHLQNYTVNATKLTVNLTNDR--YLATLTVRNLVGKSDAAVL 414
A+G++ Y +T + + + Q T+ + +V L + T+TV +L + +
Sbjct 1776 ASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRM 1835
Query 415 TIPACDFQATHPVMDLKAF-PKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQE 473
T + + V +L+ + P + L V W + ++Y L + AP ++
Sbjct 1836 T-GRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY------APAAGGPEEL 1888
Query 474 ---DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKV 530
G + LR NL Y +TV PVY +G G S ++ V+
Sbjct 1889 VPIPGNTNYAILR-NLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNP 1945
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLY 588
N + WD P G + Y + Y + G ++ V + L L DTLY
Sbjct 1946 TPNSLDVRWDPAP-----GPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLY 2000
Query 589 MVRMAA-YTDEGGKDGPEFTFTTPK 612
V + A Y+D G P T P+
Sbjct 2001 SVNLVALYSDGEGNPSPAQGRTLPR 2025
Score = 36.2 bits (82), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 34/125 (27%), Positives = 47/125 (38%), Gaps = 19/125 (15%)
Query 485 NLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS------KGPTVRTKKVGKNEAVLE 538
NL Y ++V P Y GPG+P + A ++ + PT T K L
Sbjct 781 NLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMK-------LS 833
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNETA-VNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
W P G ++ Y + Y + G ET V V T L L T Y + + A
Sbjct 834 WSGAP-----GKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYA 888
Query 598 EGGKD 602
G D
Sbjct 889 SGAGD 893
>sp|Q9P232|CNTN3_HUMAN Contactin-3 OS=Homo sapiens OX=9606 GN=CNTN3
PE=1 SV=3
Length=1028
Score = 44.7 bits (104), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 43/159 (27%), Positives = 67/159 (42%), Gaps = 12/159 (8%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP- 273
D + + P PP N+ V E + +L+W ++ Y+IQ RT + W +
Sbjct 591 DLIVRGSPGPPENVKV--DEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTT 648
Query 274 -PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF 332
PE + TV +L P+ EY FR+ + G G S SE+ T E P PS
Sbjct 649 VPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVR--TEEAVPEVPPS- 705
Query 333 WYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTL 370
+ + G R+ + + W +P NG+ Y V
Sbjct 706 ----EVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAF 740
Score = 38.5 bits (88), Expect = 0.32, Method: Compositional matrix adjust.
Identities = 32/139 (23%), Positives = 61/139 (44%), Gaps = 9/139 (6%)
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y + +R +TW Q + R F + + P++ Y ++ G+G +S
Sbjct 736 YVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEG---PFSPV 792
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
+ + E+ P+ APS S ++ +++ W T+P +NG +L YEV W
Sbjct 793 TTVFSAEEEPTVAPSQVSANSLSSSE----IEVSWNTIPWKLSNGHLLGYEVRY--WNGG 846
Query 377 LQNYTVNATKLTVNLTNDR 395
+ + + K+ N T+ R
Sbjct 847 GKEESSSKMKVAGNETSAR 865
Score = 35.0 bits (79), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 34/124 (27%), Positives = 52/124 (42%), Gaps = 8/124 (6%)
Query 482 LRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
LRG L + Y V + G G ++ K+ PPS+ P + +L W+
Sbjct 866 LRG-LKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWE 924
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAV-NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
Q+ + Y +FYRT N V N + + E L + D Y++ + A TD
Sbjct 925 QVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVL-PIKED--YIIEVKATTD-- 979
Query 600 GKDG 603
G DG
Sbjct 980 GGDG 983
Score = 35.0 bits (79), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 26/107 (24%), Positives = 43/107 (40%), Gaps = 5/107 (5%)
Query 501 ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
+GP SP + ++ P V + +E + W+ +P + NG + Y + Y
Sbjct 785 GEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWN 844
Query 561 IIGNE---TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
G E + + V + T L L S+ Y + AY G GP
Sbjct 845 GGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGA--GP 889
>sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 OS=Rattus norvegicus
OX=10116 GN=Epha5 PE=1 SV=1
Length=1005
Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 26/72 (36%), Positives = 37/72 (51%), Gaps = 4/72 (6%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L+W P + IIL+Y I+Y KD T I S ++ T + LKP + YVF+I
Sbjct 487 ISLSWQEPDRPNGIILEYEIKYFEKDQETSYTI----IKSKETTITAEGLKPASVYVFQI 542
Query 300 RCMKEDGKGYWS 311
R G G +S
Sbjct 543 RARTAAGYGVFS 554
Score = 43.9 bits (102), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 44/145 (30%), Positives = 61/145 (42%), Gaps = 11/145 (8%)
Query 504 PGSPE--SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI 561
PG+ + S+ QA PS V+ K+ KN L W + D NG I Y I Y
Sbjct 454 PGTRQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQE--PDRPNGIILEYEIKYFEK 511
Query 562 IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTF-TTPKFA----Q 615
+ + S T T L ++Y+ ++ A T G G F F TTP F Q
Sbjct 512 DQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFGASNDQ 571
Query 616 GEIEAIVVPVCLA-FLLTTLLGVLF 639
+I I V V + LL ++G L
Sbjct 572 SQIPIIGVSVTVGVILLAVMIGFLL 596
>sp|Q00546|TENR_CHICK Tenascin-R OS=Gallus gallus OX=9031 GN=TNR
PE=1 SV=1
Length=1353
Score = 43.5 bits (101), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 86/382 (23%), Positives = 146/382 (38%), Gaps = 51/382 (13%)
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQI-PPED 276
+ + + P NL V + S L+LTW N ++ Y + Y T + ++ P D
Sbjct 589 FTTEIDAPKNLRVGSRTPAS--LELTWDNSEAEA---HSYRVVYSTLAGEHYHEVLVPRD 643
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSFWYK 335
T T + T+ DL P TEY I + + S+++ T R +P
Sbjct 644 TGPTTRA-TLADLVPGTEYGIGISAVMD---------SQQSVPATMNARTELDSPRDLLV 693
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV--NATKLTVNLTN 393
+ T ++ L W +A G I Y VT T TV N ++LT++
Sbjct 694 TASTET----SISLSWT-----KAMGPIDHYRVTFTPASGMASEVTVSRNESQLTLSELE 744
Query 394 DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK-AFPKDNMLWVEWTTPRESVKK 452
T+++ G+ + T+ A F P+ L + + + + W+ P +
Sbjct 745 PGTEYTISIIAERGRQQSLEATVDA--FTGVRPITQLHFSQLTSSSVNITWSDPSPPADR 802
Query 453 YILEWCVLSDKAPCITDWQQE--DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
+L + ++AP QQ DGT L G L S YL+++ V+ P +
Sbjct 803 LVLTYSPRDEEAP-----QQLALDGTRRHASLTG-LRPSTEYLVSLVAVHGAVSSEPVTG 856
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ--LPVDVQNGFIRNYTIFYRTIIGNETAV 568
P +R + ++ V+ W P D +Y I YR G +
Sbjct 857 SITTGMDAPKD---LRVGNITQDSMVIYWSPPVAPFD-------HYRISYRAAEGRTDST 906
Query 569 NVDSSHTEYTLSSLTSDTLYMV 590
+ + TEY + L T Y +
Sbjct 907 AIGNDATEYIMRLLQPATKYEI 928
Score = 40.8 bits (94), Expect = 0.070, Method: Compositional matrix adjust.
Identities = 57/231 (25%), Positives = 93/231 (40%), Gaps = 22/231 (10%)
Query 383 NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA-CDFQATHPVMDLKAFPKDNMLWV 441
+AT+ + L + V+++ G+ ++ V +I A V P + +L
Sbjct 911 DATEYIMRLLQPATKYEIGVKSVRGREESEVASITTYTAMDAPLGVTATNITPTEALL-- 968
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
+W P V+ Y+L + + + QE Y NL S Y TV
Sbjct 969 QWNPPLMDVESYVLVLTRHTGETILVDGINQE-------YQLTNLQPSTTY--TVAMYAT 1019
Query 502 DGPGSPESIKAYLKQA--PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
+GP + ++I PP+ + +V + A+L W PV G I NY + YR
Sbjct 1020 NGPLTSQTISTNFTTLLDPPTN---LTASEVTRRSALLSWVP-PV----GDIENYILTYR 1071
Query 560 TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ G+ + VD+ T L L+ T Y VR+ A + TFTT
Sbjct 1072 STDGSRKELIVDAEDTWIRLEGLSETTQYTVRLQAAQNAMRSGFISTTFTT 1122
>sp|Q7ZW34|CNTN5_DANRE Contactin-5 OS=Danio rerio OX=7955 GN=cntn5
PE=2 SV=1
Length=1056
Score = 43.5 bits (101), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 88/366 (24%), Positives = 144/366 (39%), Gaps = 50/366 (14%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQI---PPEDTA 278
P PP VI E +S L+W++ I YN+Q R+ + W + P T
Sbjct 627 PGPPG--VVIVEEITASTATLSWSHGVDNHSPITTYNVQARSPVSLGWQTVKTDPDPVTG 684
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI-TYEDRPSKAPSFWYKID 337
S S+ V DL P+ EY FR+ G G D S + + T E PS AP+ +
Sbjct 685 SMESAMAV-DLNPWVEYEFRVVATNSIGTG---DPSPPSRAVRTKEAVPSVAPA---NVR 737
Query 338 PSHTQGYRTVQLVWKTLPPFEANGK----ILDYEVTLTR-WKSHLQNYTVNATKLTVNLT 392
+ + + V + W+ + NG+ I+ + V TR WK + +A T
Sbjct 738 GGNGRRHELV-ISWEPVSEEYQNGEGFGYIVAFRVNGTRGWKEKM---VTSADSTTYKYR 793
Query 393 NDRY--LATLTVRNLV--GKSD---AAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWT 444
++ + L VR V K D + V+T+ + + + P +++AF + + V W
Sbjct 794 DETFPPLTPFEVRVGVYNNKGDGPFSEVVTVFSAEGEPREPPSEVQAFAVSSSEIKVLWK 853
Query 445 TPRESVKKYILEWCVLSDKAPCITDW----QQEDGTVHRT------YLRGNLAESKCYLI 494
P + + + ++ W Q+E G RT L L + YL+
Sbjct 854 PPSPGLGR---------PQGYEVSFWKDVEQEELGKKKRTLGNETNMLLSGLDGNTQYLV 904
Query 495 TVTPVYADGPG-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
+V + G G S ++K K+ PS P N L WD + +
Sbjct 905 SVKGFNSAGQGPSSTAVKISTKKNAPSLPPGNLMWIQEGNNVSLSWDPVKARDNESEVIG 964
Query 554 YTIFYR 559
Y + R
Sbjct 965 YKVLLR 970
>sp|Q9BMN8|LAR_CAEEL Tyrosine-protein phosphatase Lar-like OS=Caenorhabditis
elegans OX=6239 GN=ptp-3 PE=1 SV=1
Length=2200
Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 15/153 (10%)
Query 467 ITDWQQEDGTVHR--TYLRGNLAESKCYLITVTPVYADGPGSPES--IKAYLKQAPPSKG 522
I +W+Q D T + G +S+ Y + V ++G SP S + +Q P +
Sbjct 483 IREWKQHDAKSDEFMTTINGLEPDSR-YFVRVIAQNSEG-DSPLSTLVTVATRQGIPGQP 540
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
P + K + L WD+ + + + YT+ Y T G E + + S H ++ ++ L
Sbjct 541 PMLTVKALDSRRMQLTWDK---PLYSSPVVGYTVRYNTSDG-EKELTLTSPHEKHVVTGL 596
Query 583 TSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ 615
D Y R+AAY+D G + FT P ++
Sbjct 597 HPDKYYYFRVAAYSDRGQGE-----FTEPMISK 624
Score = 38.1 bits (87), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 74/339 (22%), Positives = 125/339 (37%), Gaps = 31/339 (9%)
Query 222 PNPPHNLSVINSEELSSI-LKLTWTNPSIKSVIILKY--------NIQYRTKDASTWSQI 272
P+ P N N+E S+ +KLTW P+ + +L Y N + + S +
Sbjct 750 PSAPRNF---NAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIV 806
Query 273 PPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF 332
D S++ F + L P TEY FR+ +G G ++SE S IT + P +AP
Sbjct 807 MIRD--SSKRYFELDSLDPNTEYSFRLNAFNRNGDG---EFSERKSIIT-QGIPPEAPEI 860
Query 333 WYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY----TVNATKLT 388
+ + ++ WK +P + N ++ R + + +Y TV+ T L+
Sbjct 861 -VSVSLDRDEPPVVARIEWK-MPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLS 918
Query 389 VNLT----NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
++ Y L N G+S A TI +D++ + V W
Sbjct 919 TTISGLWMGVVYDVLLAAENREGRSQNATETIATPVGSPDGEPIDVQYEVMKGKIVVSWR 978
Query 445 TPRESVKK-YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADG 503
P E + I + + D ++ T + + YL V G
Sbjct 979 PPSEEKRNGNITSYKAILSAMDATADRYEQPVPAPSTSSTFEVNVRRAYLFKVAAATMKG 1038
Query 504 PGSPESIKAYLKQAPPSKGP--TVRTKKVGKNEAVLEWD 540
G + GP VR + + AV++WD
Sbjct 1039 IGPYSPVLTINPDPAALVGPPTNVRVEATSNSTAVVQWD 1077
Score = 36.2 bits (82), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 96/495 (19%), Positives = 177/495 (36%), Gaps = 72/495 (15%)
Query 163 EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 222
EW H D K+ T ++ + YFV V A+N+ G + + P
Sbjct 485 EWKQH---DAKSDEFMTTINGLEPDSRYFVR----VIAQNSEGDSPLSTLVTVATRQGIP 537
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P L+V + S ++LTW P + S ++ Y ++Y T D + S
Sbjct 538 GQPPMLTVKALD--SRRMQLTWDKP-LYSSPVVGYTVRYNTSDGEKELTL-----TSPHE 589
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
V L P Y FR+ + G+G +++E T P +P+ I +
Sbjct 590 KHVVTGLHPDKYYYFRVAAYSDRGQG---EFTEPMISKTIASIPLSSPT----IVSAAAT 642
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTV 402
++V++ WK + NG + Y + R + + T N + + D + L
Sbjct 643 SSKSVEIRWKGPEQKKLNGVLTAYRINYFRLE---DSKTANLESVEYDEDMDDSSSFLDR 699
Query 403 RNLVGKSDAAVLTI----------------------PACDFQATHPVMDLKAFPKD---- 436
++V SDA + P + + D+ + P++
Sbjct 700 MSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPESSIRVVKTLEDVPSAPRNFNAE 759
Query 437 ----NMLWVEWTTPRESVKKYILEWCVLSDKA----PCITDWQQED-----GTVHRTYLR 483
+ + W P + +L + V D+ P + ++ + R +
Sbjct 760 LTSATSVKLTWDAP-AAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRYFEL 818
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE----AVLEW 539
+L + Y + +G G K+ + Q P + P + + + ++E A +EW
Sbjct 819 DSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLDRDEPPVVARIEW 878
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVN---VDSSHTEYTLSSLTSDTLYMVRMAAYT 596
+ I Y ++ R ++ V VD + T+S L +Y V +AA
Sbjct 879 KMPKMKPNETPIEKYNLWLRAQGYPDSYVKAKTVDGTDLSTTISGLWMGVVYDVLLAAEN 938
Query 597 DEGGKDGPEFTFTTP 611
EG T TP
Sbjct 939 REGRSQNATETIATP 953
Score = 35.0 bits (79), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 98/421 (23%), Positives = 149/421 (35%), Gaps = 61/421 (14%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP ++++ S S + +TW P I KY + YR K + S + + +S
Sbjct 339 PPPPVNIVVSSVTSESVVITWKPPKYNEAIN-KYVVNYRLKYSEGRSS-RGKTMETLENS 396
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+ L F Y F +R G G S E T +P+ AP + P
Sbjct 397 LVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQ---TKPSKPATAP-----VSPQARSL 448
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLT---------RWKSHLQNYTVNATKLTVNLTND 394
R LV K P + NG I Y+V T WK H T + +
Sbjct 449 NRDSILV-KWGPCEQPNGLITGYKVYYTNDLVTTPIREWKQHDAKSDEFMTTINGLEPDS 507
Query 395 RYLATLTVRNLVGKSDAAVLTIPAC--DFQATHPVMDLKAFPKDNMLWVEWTTPRES--V 450
RY + +N G S + L A P++ +KA M + W P S V
Sbjct 508 RYFVRVIAQNSEGDSPLSTLVTVATRQGIPGQPPMLTVKALDSRRM-QLTWDKPLYSSPV 566
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTV--HRTYLRGNLAESKCYLITVTPVYADGPGS-P 507
Y + + +D ++E H ++ L K Y V G G
Sbjct 567 VGYTVRYNT--------SDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFT 618
Query 508 ESIKAYLKQAPPSKGPTVRTKKVGKNEAV-LEWDQLPVDVQNGFIRNYTIFYRTIIGNET 566
E + + + P PT+ + +++V + W NG + Y I Y + ++T
Sbjct 619 EPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRLEDSKT 678
Query 567 A----------------------VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
A V V S T Y LS L + Y + +AA T +G GP
Sbjct 679 ANLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGY--GP 736
Query 605 E 605
E
Sbjct 737 E 737
>sp|Q03145|EPHA2_MOUSE Ephrin type-A receptor 2 OS=Mus musculus
OX=10090 GN=Epha2 PE=1 SV=3
Length=977
Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 54/205 (26%), Positives = 88/205 (43%), Gaps = 23/205 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW----DGGRETHLETNFTLKSEW-ATHKFADCKAK---R 176
PP P L+ I G K+ W D G + + T + W + + C+A
Sbjct 329 PPSAPNYLTAI-GMGAKVELRWTAPKDTGGRQDIVYSVTCEQCWPESGECGPCEASVRYS 387
Query 177 DTPTSCTVDYSTVY----FVNIEVWVEAENAL-GKVTSDHINFDPVYKVKPNPPHNLSVI 231
+ P + T TV +N VEA N + G VTS V + PP V
Sbjct 388 EPPHALTRTSVTVSDLEPHMNYTFAVEARNGVSGLVTSRSFRTASVSINQTEPPK---VR 444
Query 232 NSEELSSILKLTWTNPSIKSVIILKYNIQYRTK-DASTWSQIPPEDTASTRSSFTVQDLK 290
+ ++ L +TW+ P + + KY + YR K DA++++ E S T+ DL
Sbjct 445 LEDRSTTSLSVTWSIPVSQQSRVWKYEVTYRKKGDANSYNVRRTEGF-----SVTLDDLA 499
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSE 315
P T Y+ +++ + ++G+G S E
Sbjct 500 PDTTYLVQVQALTQEGQGAGSKVHE 524
>sp|Q14213|IL27B_HUMAN Interleukin-27 subunit beta OS=Homo sapiens
OX=9606 GN=EBI3 PE=1 SV=2
Length=229
Score = 42.0 bits (97), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 37/152 (24%), Positives = 67/152 (44%), Gaps = 11/152 (7%)
Query 172 CKAKRDTPTSCTV-DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
C + T TSCT+ D + V A + G +S + F + +KP+PP + +
Sbjct 79 CLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGS-SSSFVPFITEHIIKPDPPEGVRL 137
Query 231 INSEELSSILKLTWTNPS---IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
E L++ W P + LKY I+Y+ + A+ + ++ P + +SF ++
Sbjct 138 SPLAERQ--LQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEA----TSFILR 191
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
++P Y ++ G SDWS A+
Sbjct 192 AVRPRARYYVQVAAQDLTDYGELSDWSLPATA 223
>sp|Q05707|COEA1_HUMAN Collagen alpha-1(XIV) chain OS=Homo sapiens
OX=9606 GN=COL14A1 PE=1 SV=3
Length=1796
Score = 43.5 bits (101), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 114/490 (23%), Positives = 189/490 (39%), Gaps = 68/490 (14%)
Query 142 MRCEWDG--GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
MR +WD G +L L A D K + T ++ S + N E V
Sbjct 459 MRVKWDAVPGASGYLILYAPLTEGLA----GDEKEMKIGETHTDIELSGL-LPNTEYTVT 513
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
G+ SD + + +PP NL + N S+ +LTW +P+ + I Y I
Sbjct 514 VYAMFGEEASDPVTGQET-TLALSPPRNLRISNVGSNSA--RLTW-DPTSRQ--INGYRI 567
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
Y D + +++ + ++F ++ L P TEY I + ++G+ SE +G
Sbjct 568 VYNNADGTEINEVEVDPI----TTFPLKGLTPLTEYTIAIFSIYDEGQ------SEPLTG 617
Query 320 I-TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL--------DYEVTL 370
+ T E+ P++ + +ID T +R + W L E K++ EV L
Sbjct 618 VFTTEEVPAQQ---YLEIDEVTTDSFR---VTWHPLSADEGLHKLMWIPVYGGKTEEVVL 671
Query 371 TRWK-SHLQNYTVNATKLTVNLTNDRYLATL------TVRNLVGKSDAAVLTIPACDFQA 423
+ SH+ T+ V+L LA L V VG + + T PA
Sbjct 672 KEEQDSHVIEGLEPGTEYEVSL-----LAVLDDGSESEVVTAVGTTLDSFWTEPATTIVP 726
Query 424 THPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCIT-DWQQEDGTVHRTYL 482
T V + N++ + TT VK I + V + +T E+ + +
Sbjct 727 TTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMV 786
Query 483 RGNLAESKC--------YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE 534
G+ Y +TVTP+Y DG G S+ A K P S +R + N
Sbjct 787 PGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGV--SVSAPGKTLPSSGPQNLRVSEEWYNR 844
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYR--TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+ WD + ++ Y I Y+ ++ G V + +++L S Y V++
Sbjct 845 LRITWDP-----PSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKI 899
Query 593 AAYTDEGGKD 602
A G D
Sbjct 900 FASQASGFSD 909
Score = 42.4 bits (98), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 42/164 (26%), Positives = 67/164 (41%), Gaps = 8/164 (5%)
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
V WT +V+KY + + P D DGTV T L+ NL Y I V
Sbjct 369 FMVNWTHAPGNVEKYRVVYYPTRGGKP---DEVVVDGTVSSTVLK-NLMSLTEYQIAVFA 424
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
+YA + E ++ + V +N ++WD +P +G++ Y
Sbjct 425 IYAHT--ASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPG--ASGYLILYAPLT 480
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ G+E + + +HT+ LS L +T Y V + A E D
Sbjct 481 EGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASD 524
Score = 36.2 bits (82), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 48/178 (27%), Positives = 72/178 (40%), Gaps = 15/178 (8%)
Query 436 DNMLWVEW-TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
+N + V+W P S Y++ + L++ + + + G H L + Y +
Sbjct 456 ENSMRVKWDAVPGAS--GYLILYAPLTEGLAG-DEKEMKIGETHTDIELSGLLPNTEYTV 512
Query 495 TVTPVYADGPGSP-ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
TV ++ + P + L +PP +R VG N A L WD P Q I
Sbjct 513 TVYAMFGEEASDPVTGQETTLALSPPRN---LRISNVGSNSARLTWD--PTSRQ---ING 564
Query 554 YTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
Y I Y G E V VD T + L LT T Y + + + DEG + FTT
Sbjct 565 YRIVYNNADGTEINEVEVDPI-TTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTT 621
>sp|Q9HCK4|ROBO2_HUMAN Roundabout homolog 2 OS=Homo sapiens OX=9606
GN=ROBO2 PE=1 SV=2
Length=1378
Score = 43.5 bits (101), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 47/173 (27%), Positives = 74/173 (43%), Gaps = 19/173 (11%)
Query 441 VEWTTPRESVKKYILEWCVLSDKAPCI---TDWQQEDGTV--HRTYLRGNLAESKCYLIT 495
V WT R+ ++I + V+ + + + WQ D V R+ + NL + Y I
Sbjct 654 VTWTVDRQ--PQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIK 711
Query 496 VTPVYADGPGSPESIKAY--LKQAPPSKGPTVRTKKVGKNEAV---LEWDQLPVDVQNGF 550
V P + + G K ++AP + +V VG + + WD P D QNG
Sbjct 712 VRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGI 771
Query 551 IRNYTIFYRTIIGNETAVN----VDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
I+ Y I+ +GNET + VD++ + L Y V +AA T G
Sbjct 772 IQEYKIW---CLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAG 821
>sp|P54296|MYOM2_HUMAN Myomesin-2 OS=Homo sapiens OX=9606 GN=MYOM2
PE=1 SV=3
Length=1465
Score = 43.1 bits (100), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 35/120 (29%), Positives = 53/120 (44%), Gaps = 8/120 (7%)
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTKDAS 267
S+H + +P P ++L+ + S L + W P S + Y + +R +DA
Sbjct 800 SEHFKCEAWTMPEPGPAYDLTFCEVRDTS--LVMLWKAPVYSGSSPVSGYFVDFREEDAG 857
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
W + TAS V DL+ YVFR+R + +G G SD SE + E RP
Sbjct 858 EWITVNQTTTAS--RYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEP---VLVEARPG 912
Score = 36.2 bits (82), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 66/252 (26%), Positives = 103/252 (41%), Gaps = 50/252 (20%)
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
F V L +Y+FR++ + G S+ S+E+ I + + PS Y I + G
Sbjct 669 FVVHGLTTGEQYIFRVKAVNAVG---MSENSQESDVIKVQAALT-VPSHPYGITLLNCDG 724
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN-YTVNATKLTVNLTNDRYLATLTV 402
+ ++ L WK +P F IL Y L + + H +N + VN++ + LTV
Sbjct 725 H-SMTLGWK-VPKFSGGSPILGY--YLDKREVHHKNWHEVNSSPSKPTI--------LTV 772
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD 462
L S I A + D P ++ WT P E Y L +C + D
Sbjct 773 DGLTEGS-LYEFKIAAVNLAGIGEPSD----PSEHFKCEAWTMP-EPGPAYDLTFCEVRD 826
Query 463 -------KAPC----------ITDWQQEDG----TVHRT-----YLR-GNLAESKCYLIT 495
KAP D+++ED TV++T YL+ +L + K Y+
Sbjct 827 TSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTASRYLKVSDLQQGKTYVFR 886
Query 496 VTPVYADGPGSP 507
V V A+G G P
Sbjct 887 VRAVNANGVGKP 898
>sp|P35331|NRCAM_CHICK Neuronal cell adhesion molecule OS=Gallus
gallus OX=9031 PE=1 SV=1
Length=1284
Score = 43.1 bits (100), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 42/157 (27%), Positives = 71/157 (45%), Gaps = 23/157 (15%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYR--TKDASTWSQIPPEDT 277
+PNPP +L + E S ++L+W + I + I+Y + W T
Sbjct 621 ARPNPPLDLELTGQLERS--IELSWVPGEENNSPITNFVIEYEDGLHEPGVWHY----QT 674
Query 278 ASTRSSFTVQ-DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
S TVQ L P+ Y FR+ + E G+ S+ SE+ +T P +
Sbjct 675 EVPGSHTTVQLKLSPYVNYSFRVIAVNEIGRSQPSEPSEQY--LTKSANPDE-------- 724
Query 337 DPSHTQGYRT----VQLVWKTLPPFEANGKILDYEVT 369
+PS+ QG + + + W++L F++NG L Y+V+
Sbjct 725 NPSNVQGIGSEPDNLVITWESLKGFQSNGPGLQYKVS 761
Score = 40.4 bits (93), Expect = 0.095, Method: Compositional matrix adjust.
Identities = 153/748 (20%), Positives = 270/748 (36%), Gaps = 116/748 (16%)
Query 23 ELLDPCGYIS-PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTI 81
E+ DP I P+ V+Q + + CV+K D + ++W ++ +P ++ +
Sbjct 517 EVKDPTMIIKQPQYKVIQRSAQASFECVIKH---DPTLIPT--VIWLKDNNELPDDERFL 571
Query 82 I---NRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLP--------PEKPK 130
+ N T +VT D + TC + T +T+++ P P P
Sbjct 572 VGKDNLTIMNVTDKDDGTY----TCIVNTTLDSVSASAVLTVVAAPPTPAIIYARPNPPL 627
Query 131 NLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTS-CTVDYST 188
+L + + W G E + TNF ++ E H+ + + P S TV
Sbjct 628 DLELTGQLERSIELSWVPGEENNSPITNFVIEYEDGLHEPGVWHYQTEVPGSHTTVQLKL 687
Query 189 VYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNP---PHNLSVINSEELSSILKLTWT 245
+VN V A N +G+ + + K NP P N+ I SE + L +TW
Sbjct 688 SPYVNYSFRVIAVNEIGRSQPSEPSEQYLTK-SANPDENPSNVQGIGSEPDN--LVITWE 744
Query 246 NPSIKSVII----LKYNIQYRTKDAS-TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
S+K L+Y + +R KD W+ + + S + V F Y +++
Sbjct 745 --SLKGFQSNGPGLQYKVSWRQKDVDDEWTSV----VVANVSKYIVSGTPTFVPYEIKVQ 798
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
+ + G ++ E G + ED P AP H ++ W +P
Sbjct 799 ALNDLG---YAPEPSEVIGHSGEDLPMVAPGNVQ----VHVINSTLAKVHWDPVPLKSVR 851
Query 361 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL-----------TVRNLVGKS 409
G + Y+V + +S + + K + ++ L VR + GK
Sbjct 852 GHLQGYKVYYWKVQSLSRRSKRHVEKKILTFRGNKTFGMLPGLEPYSSYKLNVRVVNGKG 911
Query 410 DAAV-----------LTIPACDFQATHPVMDLKAFPKDNMLWVEW---TTPRESVKKYIL 455
+ + P + T+P +D L +EW T P + YIL
Sbjct 912 EGPASPDKVFKTPEGVPSPPSFLKITNPTLD--------SLTLEWGSPTHPNGVLTSYIL 963
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP--ESIKAY 513
++ +++ + + + NL S Y + G GS E
Sbjct 964 KFQPINNTHELGPLVEIRIPANESSLILKNLNYSTRYKFYFNAQTSVGSGSQITEEAVTI 1023
Query 514 LKQAP---PSKG--------PTVR--TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
+ +A P+ G P +R T + A + W+ D N ++ +
Sbjct 1024 MDEAGILRPAVGAGKVQPLYPRIRNVTTAAAETYANISWEYEGPDHANFYVEYGVAGSKE 1083
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
E V+ S + + L LT T Y VR+ A G + + T P A +++
Sbjct 1084 DWKKEI---VNGSRSFFVLKGLTPGTAYKVRVGAEGLSGFRSSEDLFETGPAMASRQVDI 1140
Query 621 IV----VPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF 676
+ + A L L+ ++ CF +R+ K+ P K + H P
Sbjct 1141 ATQGWFIGLMCAVALLILILLIVCFIRRNKGGKY-------PVKE---KEDAHADPEIQP 1190
Query 677 NSKDQMYSDGNFTDVSVVEIEANDKKPF 704
+D DG F + +E +A D KP
Sbjct 1191 MKED----DGTFGEYRSLESDAEDHKPL 1214
>sp|Q9Y6N7|ROBO1_HUMAN Roundabout homolog 1 OS=Homo sapiens OX=9606
GN=ROBO1 PE=1 SV=1
Length=1651
Score = 43.1 bits (100), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 42/133 (32%), Positives = 61/133 (46%), Gaps = 15/133 (11%)
Query 485 NLAESKCYLITVTPVYADGPGSPESIK--AYLKQAP--PSKGPTVRTKKVGKNEAVL-EW 539
+L + Y I P + + G+ IK L++AP P +G TV +K G A+L W
Sbjct 740 DLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTV-SKNDGNGTAILVSW 798
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVN----VDSSHTEYTLSSLTSDTLYMVRMAAY 595
P D QNG ++ Y ++ +GNET + VD S + L Y V +AA
Sbjct 799 QPPPEDTQNGMVQEYKVW---CLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAAS 855
Query 596 TDEGG--KDGPEF 606
T G K P+F
Sbjct 856 TGAGSGVKSEPQF 868
>sp|Q95118|IL2RG_BOVIN Cytokine receptor common subunit gamma
OS=Bos taurus OX=9913 GN=IL2RG PE=2 SV=1
Length=379
Score = 42.4 bits (98), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 30/98 (31%), Positives = 48/98 (49%), Gaps = 11/98 (11%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
V P P NL++ N E L+L+W+N + L++ +QYR+ +W+ E +
Sbjct 159 VIPWAPENLTLRNLSEFQ--LELSWSNRYLDHC--LEHLVQYRSDRDRSWT----EQSVD 210
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKG---YWSDWS 314
R SF++ + Y FR+R G +WSDWS
Sbjct 211 HRHSFSLPSVDAQKLYTFRVRSRYNPLCGSAQHWSDWS 248
>sp|Q810U3|NFASC_MOUSE Neurofascin OS=Mus musculus OX=10090 GN=Nfasc
PE=1 SV=1
Length=1240
Score = 42.7 bits (99), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 62/242 (26%), Positives = 103/242 (43%), Gaps = 32/242 (13%)
Query 191 FVNIEVWVEAENALGKVTSDHINF-DPVYKVKPNPPH-NLSVINSE-ELSSILKLTWTNP 247
+VN + V A N +G S H + Y+ PP N S + E + +++TWT
Sbjct 695 YVNYQFRVIAVNEVG---SSHPSLPSERYRTSGAPPESNPSDVKGEGTRKNNMEITWTPM 751
Query 248 SIKSVII--LKYNIQYRTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ S L+Y +++R ++ TW+ + S + V + Y R++ +
Sbjct 752 NATSAFGPNLRYIVKWRRRETRETWNNV-----TVWGSRYVVGQTPVYVPYEIRVQAEND 806
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
GKG D G + ED PS AP + P+ T+ L W P NG ++
Sbjct 807 FGKGPEPD---TIIGYSGEDLPS-APRRFRVRQPN----LETINLEWDH--PEHPNGILI 856
Query 365 DYEVTLTRW------KSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTI 416
Y + + K ++N++ N TK +V + RY +L+ R VG +AA
Sbjct 857 GYILRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRFSLSARTQVGSGEAATEES 916
Query 417 PA 418
PA
Sbjct 917 PA 918
Score = 36.6 bits (83), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 45/191 (24%), Positives = 73/191 (38%), Gaps = 8/191 (4%)
Query 122 SGLPPEKPKNLSCIVNEGKK---MRCEWDGGRETH-LETNFTLKSEWATHKFADCKAKRD 177
SG PPE N S + EG + M W T N +W + +
Sbjct 723 SGAPPES--NPSDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRETWNNVT 780
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
S V T +V E+ V+AEN GK + P+ P V L
Sbjct 781 VWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPDTIIGYSGEDLPSAPRRFRV-RQPNLE 839
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+I L W +P + I++ Y ++Y + + + E+ + ++ F+VQ P + Y F
Sbjct 840 TI-NLEWDHPEHPNGILIGYILRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRF 898
Query 298 RIRCMKEDGKG 308
+ + G G
Sbjct 899 SLSARTQVGSG 909
>sp|Q9UMZ3|PTPRQ_HUMAN Phosphatidylinositol phosphatase PTPRQ
OS=Homo sapiens OX=9606 GN=PTPRQ PE=1 SV=2
Length=2332
Score = 42.7 bits (99), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 78/333 (23%), Positives = 128/333 (38%), Gaps = 46/333 (14%)
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
D ++ F +L PFT Y I G G S+ S P P +
Sbjct 393 DNSTKDLKFAFTNLTPFTMYDVYIAAETSAGTGPKSNISVFT--------PPDVPGAVFD 444
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN--LTN 393
+ + + + V++ WK P + NG I Y V + ++ + + T LT N N
Sbjct 445 LQLAEVESTQ-VRITWKK--PRQPNGIINQYRVKVLVPETGI---ILENTLLTGNNEYIN 498
Query 394 DRYLATLT--VRNLVGKSDAAV-----LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
D + V +VG + + L A +HP K FP N + T+P
Sbjct 499 DPMAPEIVNIVEPMVGLYEGSAEMSSDLHSLATFIYNSHPD---KNFPARNRAE-DQTSP 554
Query 447 RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
V++ + ITD E +Y+ L ++I+V+ G G
Sbjct 555 ------------VVTTRNQYITDIAAE----QLSYVIRRLVPFTEHMISVSAFTIMGEGP 598
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET 566
P + +Q PS + K + + +L WD P + NG I +YTI+ + N
Sbjct 599 PTVLSVRTRQQVPSSIKIINYKNISSSSILLYWD--PPEYPNGKITHYTIYAMELDTNR- 655
Query 567 AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
A + + + ++ L T Y +R+AA T G
Sbjct 656 AFQITTIDNSFLITGLKKYTKYKMRVAASTHVG 688
Score = 42.0 bits (97), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 51/174 (29%), Positives = 82/174 (47%), Gaps = 23/174 (13%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS-S 283
P N++ N S ++L++ PS + II KY I + + + E T +T S +
Sbjct 805 PENITYKNIS--SGEIELSFLPPSSPNGIIKKYTIYLKRSNGNE------ERTINTTSLT 856
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
++ LK +T+Y+ + G+G S S +T ED P P G
Sbjct 857 QNIKVLKKYTQYIIEVSASTLKGEGVRS---APISILTEEDAPDSPPQ---DFSVKQLSG 910
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRW-KSHLQNYTVNATKLTVNLTNDRY 396
TV+L W+ PP E NG IL Y V + W +S L+ T+N T+ ++ L++ Y
Sbjct 911 V-TVKLSWQ--PPLEPNGIILYYTVYV--WNRSSLK--TINVTETSLELSDLDY 957
Score = 40.0 bits (92), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 80/345 (23%), Positives = 138/345 (40%), Gaps = 39/345 (11%)
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
D A+ + S+ ++ L PFTE++ + G+G + S T + PS YK
Sbjct 565 DIAAEQLSYVIRRLVPFTEHMISVSAFTIMGEGPPTVLSVR----TRQQVPSSIKIINYK 620
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH--LQNYTVNATKLTVNLTN 393
S + + L W PP NGKI Y + ++ Q T++ + L L
Sbjct 621 NISSSS-----ILLYWD--PPEYPNGKITHYTIYAMELDTNRAFQITTIDNSFLITGLKK 673
Query 394 -DRYLATLTVRNLVGKSDAA----VLTIPACDFQATHP----VMDLKAFPKDNMLWVEWT 444
+Y + VG+S + + + D + P V+D+ A + + ++W+
Sbjct 674 YTKYKMRVAASTHVGESSLSEENDIFVRTSEDEPESSPQDVEVIDVTA----DEIRLKWS 729
Query 445 TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
P E I+ + VL I ++ + LR NL Y I+V G
Sbjct 730 PP-EKPNGIIIAYEVLYKN---IDTLYMKNTSTTDIILR-NLRPHTLYNISVRSYTRFGH 784
Query 505 GSPES--IKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI 561
G+ S + + P P + K + E +E LP NG I+ YTI+ +
Sbjct 785 GNQVSSLLSVRTSETVPDSAPENITYKNISSGE--IELSFLPPSSPNGIIKKYTIYLKRS 842
Query 562 IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT--DEGGKDGP 604
GNE ++++ + L T Y++ ++A T EG + P
Sbjct 843 NGNEER-TINTTSLTQNIKVLKKYTQYIIEVSASTLKGEGVRSAP 886
Score = 37.0 bits (84), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 76/346 (22%), Positives = 135/346 (39%), Gaps = 64/346 (18%)
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
S +L+ +T+Y+ +I E KG+ ++ + T ED P +P I+
Sbjct 1151 SIYFDNLEKYTDYILKITPSTE--KGFSDTYTAQLYIKTEEDVPETSPI----INTFKNL 1204
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRY-----L 397
+V L W PP + NG I+ Y++TL + +NY+ +T+D Y L
Sbjct 1205 SSTSVLLSWD--PPVKPNGAIISYDLTL---QGPNENYSF--------ITSDNYIILEEL 1251
Query 398 ATLTV-------RNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWT---TP 446
+ T+ R G +++L + P +L + +W++W+ P
Sbjct 1252 SPFTLYSFFAAARTRKGLGPSSILFFYTDESVPLAPPQNLTLINCTSDFVWLKWSPSPLP 1311
Query 447 RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC--------YLITVTP 498
VK Y + + E T++ + G E+K Y I V+
Sbjct 1312 GGIVKVYSFKI------------HEHETDTIYYKNISGFKTEAKLVGLEPVSTYSIRVSA 1359
Query 499 VYADGPGSPES--IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
G G+ S +K +++ P ++ +++WD P NG I Y +
Sbjct 1360 FTKVGNGNQFSNVVKFTTQESVPDVVQNMQCMATSWQSVLVKWD--PPKKANGIITQYMV 1417
Query 557 FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
T+ N T V+ YT L ++T Y+ ++ A T G D
Sbjct 1418 ---TVERNSTKVSPQDHM--YTFIKLLANTSYVFKVRASTSAGEGD 1458
>sp|Q86VF2|IGFN1_HUMAN Immunoglobulin-like and fibronectin type
III domain-containing protein 1 OS=Homo sapiens OX=9606 GN=IGFN1
PE=1 SV=2
Length=1251
Score = 42.4 bits (98), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 48/184 (26%), Positives = 77/184 (42%), Gaps = 20/184 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW-----DGGRETH---LETNFTLKSEWATHKFADCKAKR 176
PP+ P + G +R W +GGR +E +S W K + A
Sbjct 646 PPQGPMEVQDCHRAGVCLR--WRPPRDNGGRTVECYVVERRQAGRSTWL--KVGEAPADS 701
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
T T V+ Y + V +E A + S+ I P + P P +++++
Sbjct 702 TTFTDAHVEPGRKYTFRVRA-VTSEGAGEALESEEILVAP--EALPKAPSAPAILSAS-- 756
Query 237 SSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
S + LTWT P S IL Y I+ R K ++TW+ + D +TV D++ +Y
Sbjct 757 SQGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAV--NDQPVPERRWTVADVRQGCQY 814
Query 296 VFRI 299
FR+
Sbjct 815 EFRV 818
Score = 35.8 bits (81), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 42/149 (28%), Positives = 66/149 (44%), Gaps = 12/149 (8%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK-YNIQYRTKDASTWSQIPPEDTAS 279
KP+PP + + + L W P ++ Y ++ R STW ++ S
Sbjct 643 KPDPPQGPMEVQDCHRAGVC-LRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPADS 701
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
T +FT ++P +Y FR+R + +G G + SEE + E P KAPS + S
Sbjct 702 T--TFTDAHVEPGRKYTFRVRAVTSEGAGEALE-SEEIL-VAPEALP-KAPSAPAILSAS 756
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEV 368
+QG + L W T P + IL Y +
Sbjct 757 -SQG---ITLTW-TAPRGPGSAHILGYLI 780
>sp|Q95LF0|I13R2_CANLF Interleukin-13 receptor subunit alpha-2
OS=Canis lupus familiaris OX=9615 GN=IL13RA2 PE=2 SV=1
Length=386
Score = 42.0 bits (97), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 55/201 (27%), Positives = 82/201 (41%), Gaps = 23/201 (11%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL--KSEWATHKFADCK---AKRDTPTSC 182
K +++ C+ + + C W G H +TN+ L E H A+C C
Sbjct 138 KIQDMDCVYYNWQYLVCSWKPGMGVHFDTNYQLFYWYEGLDHS-AECTDYIKVNGKNMGC 196
Query 183 TVDY-STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEELSSI 239
Y + + + + V + + + F VKP PP LS V NSEE++
Sbjct 197 RFPYLESSDYKDFYICVNGSSESQPIRPSYFIFQLQNIVKPMPPDYLSLTVKNSEEIN-- 254
Query 240 LKLTWTNPSIKSVIILK---YNIQYRTKDASTWSQIPPEDTAS-TRSSFTVQDLKPFTEY 295
L W P K I K Y I++ T+D +TW E+ TR+S Q L
Sbjct 255 --LKWNMP--KGPIPAKCFIYEIEF-TEDGTTWVTTTVENEIQITRTSNESQKLCFLVRS 309
Query 296 VFRIRCMKEDGKGYWSDWSEE 316
I C + G WS+WS+E
Sbjct 310 KVNIYCSDD---GIWSEWSDE 327
>sp|O89026|ROBO1_MOUSE Roundabout homolog 1 OS=Mus musculus OX=10090
GN=Robo1 PE=1 SV=1
Length=1612
Score = 42.4 bits (98), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 42/133 (32%), Positives = 61/133 (46%), Gaps = 15/133 (11%)
Query 485 NLAESKCYLITVTPVYADGPGSPESIK--AYLKQAP--PSKGPTVRTKKVGKNEAVL-EW 539
+L + Y I P + + G+ IK L++AP P + TV +K G A+L W
Sbjct 701 DLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPRSVTV-SKNDGNGTAILVTW 759
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVN----VDSSHTEYTLSSLTSDTLYMVRMAAY 595
P D QNG ++ Y ++ +GNET + VD S + SL Y V +AA
Sbjct 760 QPPPEDTQNGMVQEYKVW---CLGNETKYHINKTVDGSTFSVVIPSLVPGIRYSVEVAAS 816
Query 596 TDEGG--KDGPEF 606
T G K P+F
Sbjct 817 TGAGPGVKSEPQF 829
>sp|P97685|NFASC_RAT Neurofascin OS=Rattus norvegicus OX=10116
GN=Nfasc PE=1 SV=2
Length=1240
Score = 42.4 bits (98), Expect = 0.025, Method: Compositional matrix adjust.
Identities = 61/241 (25%), Positives = 102/241 (42%), Gaps = 32/241 (13%)
Query 191 FVNIEVWVEAENALGKVTSDHINF-DPVYKVKPNPPH-NLSVINSE-ELSSILKLTWTNP 247
+VN + V A N +G S H + Y+ PP N S + E + +++TWT
Sbjct 695 YVNYQFRVIAVNEVG---SSHPSLPSERYRTSGAPPESNPSDVKGEGTRKNNMEITWTPM 751
Query 248 SIKSVII--LKYNIQYRTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ S L+Y +++R ++ TW+ + S + V + Y R++ +
Sbjct 752 NATSAFGPNLRYIVKWRRRETRETWNNV-----TVWGSRYVVGQTPVYVPYEIRVQAEND 806
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
GKG E G + ED PS AP + P+ T+ L W P NG ++
Sbjct 807 FGKG---PEPETVIGYSGEDLPS-APRRFRVRQPN----LETINLEWDH--PEHPNGILI 856
Query 365 DYEVTLTRW------KSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTI 416
Y + + K ++N++ N TK +V + RY +L+ R VG +AA
Sbjct 857 GYTLRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRFSLSARTQVGSGEAATEES 916
Query 417 P 417
P
Sbjct 917 P 917
Score = 38.1 bits (87), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 45/191 (24%), Positives = 73/191 (38%), Gaps = 8/191 (4%)
Query 122 SGLPPEKPKNLSCIVNEGKK---MRCEWDGGRETH-LETNFTLKSEWATHKFADCKAKRD 177
SG PPE N S + EG + M W T N +W + +
Sbjct 723 SGAPPES--NPSDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRETWNNVT 780
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
S V T +V E+ V+AEN GK + P+ P V L
Sbjct 781 VWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPETVIGYSGEDLPSAPRRFRV-RQPNLE 839
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+I L W +P + I++ Y ++Y + + + E+ + ++ F+VQ P + Y F
Sbjct 840 TI-NLEWDHPEHPNGILIGYTLRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRF 898
Query 298 RIRCMKEDGKG 308
+ + G G
Sbjct 899 SLSARTQVGSG 909
Score = 35.0 bits (79), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 29/123 (24%), Positives = 49/123 (40%), Gaps = 16/123 (13%)
Query 492 YLITVTPVY-------------ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
Y++ TPVY GP PE++ Y + PS R ++ LE
Sbjct 786 YVVGQTPVYVPYEIRVQAENDFGKGP-EPETVIGYSGEDLPSAPRRFRVRQPNLETINLE 844
Query 539 WD--QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
WD + P + G+ Y F T +G + N + T++++ + Y ++A T
Sbjct 845 WDHPEHPNGILIGYTLRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRFSLSART 904
Query 597 DEG 599
G
Sbjct 905 QVG 907
>sp|Q9TU69|GHR_CANLF Growth hormone receptor OS=Canis lupus familiaris
OX=9615 GN=GHR PE=2 SV=1
Length=638
Score = 42.0 bits (97), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 48/203 (24%), Positives = 83/203 (41%), Gaps = 31/203 (15%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLK--------SEWATHKFADCKAKRDT 178
EKPK C E + C W G L+ +++ EW T ++ +C
Sbjct 49 EKPKFTKCRSPELETFSCHWTDGVRHGLKNAGSVQLFYIRRSTQEW-TQEWKEC------ 101
Query 179 PTSCTVDYSTVYFVN--IEVWVEAENAL--GKVTSDHINFDPVYKVKPNPPHNLS----V 230
P + ++ YF + +W+ L T D F V+P+PP L+
Sbjct 102 PDYVSAGENSCYFNSSYTSIWIPYCIKLTSNGGTVDQKCFSVEEIVQPDPPIGLNWTLLN 161
Query 231 INSEELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 286
I+ + + +++ W P V I+LKY +QY+ + S W + P + +S V
Sbjct 162 ISLTGIHADIQVRWEPPPNADVQKGWIVLKYELQYKEVNESQWKMMDP----VSATSVPV 217
Query 287 QDLKPFTEYVFRIRCMKEDGKGY 309
L+ EY R+R + + + Y
Sbjct 218 YSLRLDKEYEVRVRSRQRNSEKY 240
>sp|Q9JMB8|CNTN6_MOUSE Contactin-6 OS=Mus musculus OX=10090 GN=Cntn6
PE=1 SV=2
Length=1028
Score = 42.0 bits (97), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 98/451 (22%), Positives = 170/451 (38%), Gaps = 44/451 (10%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSIL-KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
D + + P PP ++ V E +SS +L+W + I + IQ RT + W +
Sbjct 591 DIIVRGPPGPPEDVKV---EHISSTTSQLSWRPGPDNNSPIQIFTIQTRTPFSVGWQAVA 647
Query 274 --PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
PE + TV L P+ EY FR+ G G S SE T P+ AP
Sbjct 648 TVPEILNGQTYNATVVGLSPWVEYEFRVVAGNNIGIGEPSKPSELLR--TKASVPNVAPG 705
Query 332 FWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTL-----TRWKSHLQNYTVNAT 385
+ + G R+ + + W+ +P NG+ Y V T W + V ++
Sbjct 706 -----NINGGGGSRSELVITWEAIPEELQNGEGFGYIVMFRPVGTTAWMKE-RVALVESS 759
Query 386 KLTVNLTNDRYLATLTVR----NLVGKSDAAVLTIPAC---DFQATHPVMDLKAFPKDNM 438
K + L+ V+ N G+ + +TI + Q +++F M
Sbjct 760 KFIYRNESIMPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSVQSFSASEM 819
Query 439 --LW--VEWTTPRESVKKY-ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
W + W V Y +L W S ++ + + G V + G L + Y
Sbjct 820 EVSWNAIAWNRNTGRVLGYEVLYWTDNSKES--MIGKIRVSGNVTTKNITG-LRANTIYF 876
Query 494 ITVTPVYADGPG-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
+V G G S + K++PPS+ P K+ ++ L W+ + +
Sbjct 877 ASVRAYNTAGTGPSSLPVNVTTKKSPPSQPPANIAWKLSNSKLCLNWEHVKTMENESEVL 936
Query 553 NYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
Y I YR ++T + ++ + L D L +R + +GG PK
Sbjct 937 GYKILYRQNRQSKTHILETNNTSAELLVPFEEDYLIEIRTVS---DGGDGSSSEEIRIPK 993
Query 613 FAQGEIEAIVV--PVCLAFLLTTLLGVLFCF 641
+ + + P + +++GV +CF
Sbjct 994 MSSLSSTGVQISKPSTQSL---SMVGVFYCF 1021
>sp|Q28106|CNTN1_BOVIN Contactin-1 OS=Bos taurus OX=9913 GN=CNTN1
PE=2 SV=1
Length=1018
Score = 42.0 bits (97), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 38/155 (25%), Positives = 66/155 (43%), Gaps = 12/155 (8%)
Query 485 NLAESKCYLITVTPVYADGPGSPESI-KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLP 543
NL Y + V + G G P + + + K+APPS+ P + + + ++ WD +
Sbjct 870 NLLPDTQYFVEVRACNSAGCGPPSDMTETFTKKAPPSQPPRIISSVRSGSRYIITWDHVV 929
Query 544 VDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ Y + YR + + S+H + D Y+V + A++D G DG
Sbjct 930 ALSNESTVTGYKVLYRP--DGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSD--GGDG 985
Query 604 PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
+ K + +I+ P L FLL LG+L
Sbjct 986 ---VVSQVKISGA---SILSPCLLGFLLPA-LGIL 1013
>sp|A2A863|ITB4_MOUSE Integrin beta-4 OS=Mus musculus OX=10090
GN=Itgb4 PE=1 SV=1
Length=1818
Score = 42.0 bits (97), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 62/151 (41%), Gaps = 38/151 (25%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
LK++W P ++L Y+++Y+ + ++ + T S V+DL P YVFR+
Sbjct 1540 LKVSWQEPQCDR-MLLGYSVEYQLLNGGEMHRLNIPNPGQT--SVVVEDLLPNHSYVFRV 1596
Query 300 RCMKEDGKGYWSDWSEEASG-ITYEDR----------PSKA----------PSFWYKIDP 338
R ++G W E G IT E + P A P + + P
Sbjct 1597 RAQSQEG------WGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSP 1650
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
++QL W+ P NG IL Y VT
Sbjct 1651 D------SLQLSWER--PRRPNGDILGYLVT 1673
>sp|P28693|EPHB2_CHICK Ephrin type-B receptor 2 OS=Gallus gallus
OX=9031 GN=EPHB2 PE=1 SV=3
Length=1004
Score = 42.0 bits (97), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L+W+ P + +IL Y +QY K+ S ++ S ++ TVQ+LK T YVF++
Sbjct 453 ITLSWSQPDQPNGVILDYELQYYEKNLS---ELNSTAVKSPTNTVTVQNLKAGTIYVFQV 509
Query 300 RCMKEDGKGYWS 311
R G G +S
Sbjct 510 RARTVAGYGRYS 521
Score = 33.9 bits (76), Expect = 9.0, Method: Compositional matrix adjust.
Identities = 54/226 (24%), Positives = 92/226 (41%), Gaps = 22/226 (10%)
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL-- 460
RN ++DA + +P C + P + + + L +EWT PR+S + L + ++
Sbjct 307 RNGYYRADADPVDMP-CTTIPSAPQAVISSV-NETSLMLEWTPPRDSGGREDLVYNIICK 364
Query 461 ---SDKAPCITDW-------QQEDGTVHRTYLRGNLAESK--CYLITVTPVYADGPGSPE 508
S + C +Q T R Y+ LA ++ + V V P SP+
Sbjct 365 SCGSGRGACTRCGDNVQFAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQ 424
Query 509 --SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNE 565
S+ QA PS + + L W Q D NG I +Y + +Y +
Sbjct 425 FASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQ--PDQPNGVILDYELQYYEKNLSEL 482
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTT 610
+ V S T+ +L + T+Y+ ++ A T G G+ + F T
Sbjct 483 NSTAVKSPTNTVTVQNLKAGTIYVFQVRARTVAGYGRYSGKMYFQT 528
>sp|Q90344|EPHB2_COTJA Ephrin type-B receptor 2 OS=Coturnix japonica
OX=93934 GN=EPHB2 PE=2 SV=1
Length=987
Score = 42.0 bits (97), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L+W+ P + +IL Y +QY K+ S ++ S ++ TVQ+LK T YVF++
Sbjct 453 ITLSWSQPDQPNGVILDYELQYYEKNLS---ELNSTAVKSPTNTVTVQNLKAGTIYVFQV 509
Query 300 RCMKEDGKGYWS 311
R G G +S
Sbjct 510 RARTVAGYGRYS 521
>sp|P54764|EPHA4_HUMAN Ephrin type-A receptor 4 OS=Homo sapiens
OX=9606 GN=EPHA4 PE=1 SV=1
Length=986
Score = 42.0 bits (97), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 50/215 (23%), Positives = 82/215 (38%), Gaps = 43/215 (20%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAKRDTP 179
PP P NL VNE + EW GGR+ + N K K P
Sbjct 328 PPSAPLNLISNVNE-TSVNLEWSSPQNTGGRQ-DISYNVVCK-----------KCGAGDP 374
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINF-------DPVYKVKPNP-------- 224
+ C S V++ + ++ H N+ + V K PNP
Sbjct 375 SKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTV 434
Query 225 ------PHNLSVINSEELSSI-LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
P +++++ ++E++ + L W P + +IL+Y ++Y KD + S
Sbjct 435 TTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTA 494
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
A ++ L P T YVF +R G G +S+
Sbjct 495 ARNTD---IKGLNPLTSYVFHVRARTAAGYGDFSE 526
>sp|Q63198|CNTN1_RAT Contactin-1 OS=Rattus norvegicus OX=10116
GN=Cntn1 PE=1 SV=2
Length=1021
Score = 41.6 bits (96), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 96/396 (24%), Positives = 140/396 (35%), Gaps = 68/396 (17%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQI---PPEDTASTRSSFTVQDLKPFTEYV 296
+ LTW+ S I KY IQ +T + W PP + S+ V DL P+ EY
Sbjct 622 VALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMESAKAV-DLIPWMEYE 680
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGY-RTVQLVWKTLP 355
FR+ G G S S T P+ APS D G R + + W L
Sbjct 681 FRVVATNTLGTGEPSIPSNRIK--TDGAAPNVAPS-----DVGGGGGTNRELTITWAPLS 733
Query 356 PFEANGKILDYEVTLT-----RWKSHLQNYTVNATKLTV-NLTNDRYL---ATLT----- 401
G Y V WK K+TV N RY+ T+T
Sbjct 734 REYHYGNNFGYIVAFKPFDGEEWK-----------KVTVTNPDTGRYVHKDETMTPSTAF 782
Query 402 ---VRNLVGKSDAAVLTIP----ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI 454
V+ K D I A D + P + + V W K++
Sbjct 783 QVKVKAFNNKGDGPYSLIAVINSAQDAPSEAPTEVGVKVLSSSEISVHW--------KHV 834
Query 455 LEWCVLSDKAPCITDWQQED--GTVHRTYLRG--------NLAESKCYLITVTPVYADGP 504
LE V S + I W D HR + NL Y I V + G
Sbjct 835 LEKIVESYQ---IRYWAGHDKEAAAHRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGC 891
Query 505 G-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
G S + I+ + ++APPS+ P + + + ++ WD + + Y I YR
Sbjct 892 GPSSDVIETFTRKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKILYRP--D 949
Query 564 NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ + S+H + D Y+V + A++D G
Sbjct 950 GQHDGKLFSTHKHSIEVPIPRDGEYVVEVRAHSDGG 985
>sp|Q9MYZ9|EPOR_PIG Erythropoietin receptor OS=Sus scrofa OX=9823
GN=EPOR PE=2 SV=1
Length=509
Score = 41.2 bits (95), Expect = 0.039, Method: Compositional matrix adjust.
Identities = 43/206 (21%), Positives = 81/206 (39%), Gaps = 14/206 (7%)
Query 129 PKNLSCIVNEGKKMRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY- 186
P+ L C + + C W+ G +++ + + C + +V +
Sbjct 47 PEELLCFTERLEDLVCFWEEAGSAGVGPEDYSFSYQLEGEPWKPCHLHQGPTARGSVRFW 106
Query 187 ------STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
T FV +E+ V ++ I+ + V + +PP L +EE ++
Sbjct 107 CSLPTADTSSFVPLELRVTEVSSGAPRYHRIIHINEVVLL--DPPAGLLARRAEESGHVV 164
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
P +++Y + T++A+ Q + R+ + +L+ T Y F +R
Sbjct 165 LRWLPPPGAPMASLIRYEVNISTENAAGGVQR--VEILDGRTECVLSNLRGGTRYTFMVR 222
Query 301 C-MKEDG-KGYWSDWSEEASGITYED 324
M E G+WS WSE AS +T D
Sbjct 223 ARMAEPSFGGFWSAWSEPASLLTASD 248
>sp|Q12860|CNTN1_HUMAN Contactin-1 OS=Homo sapiens OX=9606 GN=CNTN1
PE=1 SV=1
Length=1018
Score = 41.6 bits (96), Expect = 0.040, Method: Compositional matrix adjust.
Identities = 31/120 (26%), Positives = 53/120 (44%), Gaps = 5/120 (4%)
Query 485 NLAESKCYLITVTPVYADGPGSP-ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLP 543
NL Y I V + G G P + I+A+ K+APPS+ P + + + ++ WD +
Sbjct 870 NLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVV 929
Query 544 VDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ Y + YR + + S+H + D Y+V + A++D G DG
Sbjct 930 ALSNESTVTGYKVLYRP--DGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSD--GGDG 985
>sp|Q967D7|TUTL_DROME Protein turtle OS=Drosophila melanogaster
OX=7227 GN=tutl PE=1 SV=2
Length=1531
Score = 41.6 bits (96), Expect = 0.041, Method: Compositional matrix adjust.
Identities = 30/89 (34%), Positives = 45/89 (51%), Gaps = 15/89 (17%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW-----SQIPPE 275
KP PP N+SV E+S+ +TW +P ++ I+ Y I+YRT + W QI PE
Sbjct 757 KPGPPRNVSVT---EVSNGFLITWQSPLERAHIVKFYTIKYRTD--AQWKTLNRGQIRPE 811
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+T + V++L Y FR+ E
Sbjct 812 ET-----QYLVKNLVGGRTYYFRVLANSE 835
>sp|P26954|IL3B2_MOUSE Interleukin-3 receptor class 2 subunit
beta OS=Mus musculus OX=10090 GN=Csf2rb2 PE=1 SV=1
Length=878
Score = 41.6 bits (96), Expect = 0.042, Method: Compositional matrix adjust.
Identities = 46/197 (23%), Positives = 77/197 (39%), Gaps = 19/197 (10%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL---KSEWATHKFADCKAKRDTPTSCTV 184
+P+NL C + + + C W+ +T +F L S A + C P +
Sbjct 248 QPQNLQCFFDGIQSLHCSWEVWTQTTGSVSFGLFYRPSPAAPEE--KCSPVVKEPQASVY 305
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHIN----FDPVYKVKPNPPHNLSVINSEELSSIL 240
T Y ++ V + ++ V+ H+ Y ++ PP ++N +
Sbjct 306 ---TRYRCSLPVPEPSAHSQYTVSVKHLEQGKFIMSYYHIQMEPP----ILNQTKNRDSY 358
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
L W I I + +QY+ K S W E+ +S + L+P T Y R+R
Sbjct 359 SLHWETQKIPKYIDHTFQVQYKKKSES-WKDSKTENLGRV-NSMDLPQLEPDTSYCARVR 416
Query 301 CMK-EDGKGYWSDWSEE 316
D G WS+WS E
Sbjct 417 VKPISDYDGIWSEWSNE 433
>sp|Q64632|ITB4_RAT Integrin beta-4 OS=Rattus norvegicus OX=10116
GN=Itgb4 PE=1 SV=1
Length=1807
Score = 41.2 bits (95), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 40/151 (26%), Positives = 61/151 (40%), Gaps = 38/151 (25%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
LK++W P + L Y+++Y+ + ++ + T S V+DL P YVFR+
Sbjct 1528 LKVSWQEPQCDRAL-LGYSVEYQLLNGGEMHRLNIPNPGQT--SVVVEDLLPNHSYVFRV 1584
Query 300 RCMKEDGKGYWSDWSEEASG-ITYEDR----------PSKA----------PSFWYKIDP 338
R ++G W E G IT E + P A P + + P
Sbjct 1585 RAQSQEG------WGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSP 1638
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
++QL W+ P NG IL Y VT
Sbjct 1639 D------SLQLSWER--PRRPNGDILGYLVT 1661
>sp|P40321|IL2RG_CANLF Cytokine receptor common subunit gamma
OS=Canis lupus familiaris OX=9615 GN=IL2RG PE=2 SV=1
Length=373
Score = 40.8 bits (94), Expect = 0.056, Method: Compositional matrix adjust.
Identities = 53/215 (25%), Positives = 85/215 (40%), Gaps = 21/215 (10%)
Query 121 ISGLP-PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATH---KFADCKA-- 174
+S LP PE + C V + M C W+ E TN TL + K +C
Sbjct 52 VSSLPLPE----VQCFVFNVEYMNCTWNSSSEPR-PTNLTLHYWYKNSNDDKVQECGHYL 106
Query 175 -KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS 233
R+ C + ++ V V+ + V P P NL++ N
Sbjct 107 FSREVTAGCWLQKEEIHLYETFV-VQLRDPREPRRQSTQKLKLQNLVIPWAPENLTLHNL 165
Query 234 EELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
E S L+L+W+N + L++ +QYR+ +W+ E + R+SF++ +
Sbjct 166 SE--SQLELSWSNRHLDHC--LEHVVQYRSDWDRSWT----EQSVDHRNSFSLPSVDGQK 217
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
Y FR+R G WSE + I + SK
Sbjct 218 FYTFRVRSRYNPLCGSAQRWSEWSHPIHWGSNTSK 252
>sp|P29320|EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo sapiens
OX=9606 GN=EPHA3 PE=1 SV=2
Length=983
Score = 41.2 bits (95), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 32/97 (33%), Positives = 49/97 (51%), Gaps = 4/97 (4%)
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV-DSSH 574
QA PS T++ + +N L W Q P + NG I +Y + Y ET+ + +
Sbjct 434 QAAPSPVLTIKKDRTSRNSISLSW-QEP-EHPNGIILDYEVKYYEKQEQETSYTILRARG 491
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTT 610
T T+SSL DT+Y+ ++ A T G G + +F F T
Sbjct 492 TNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFET 528
Score = 38.5 bits (88), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 78/200 (39%), Gaps = 22/200 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAK-RDT 178
PP P+N+ +NE + +W GGR+ K W + C R
Sbjct 325 PPSSPRNVISNINETSVI-LDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
Query 179 PTSCTVDYSTVYFV------NIEVWVEAENALGKVTSDHINFDPVY----KVKPNPPHNL 228
P + +TV N ++A N + +++S F V + P+P L
Sbjct 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPV--L 441
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
++ + + L+W P + IIL Y ++Y K S + ++ T+
Sbjct 442 TIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTI---LRARGTNVTISS 498
Query 289 LKPFTEYVFRIRCMKEDGKG 308
LKP T YVF+IR G G
Sbjct 499 LKPDTIYVFQIRARTAAGYG 518
>sp|P12960|CNTN1_MOUSE Contactin-1 OS=Mus musculus OX=10090 GN=Cntn1
PE=1 SV=1
Length=1020
Score = 40.8 bits (94), Expect = 0.062, Method: Compositional matrix adjust.
Identities = 97/397 (24%), Positives = 142/397 (36%), Gaps = 70/397 (18%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQI---PPEDTASTRSSFTVQDLKPFTEYV 296
+ LTW+ S I KY IQ +T + W PP + S+ V DL P+ EY
Sbjct 622 VALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMESAKAV-DLIPWMEYE 680
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGY-RTVQLVWKTLP 355
FR+ G G S S T P+ APS D G R + + W L
Sbjct 681 FRVVATNTLGTGEPSIPSNRIK--TDGAAPNVAPS-----DVGGGGGTNRELTITWAPLS 733
Query 356 PFEANGKILDYEVTLT-----RWKSHLQNYTVNATKLTV-NLTNDRYL---ATLT----- 401
G Y V WK K+TV N RY+ T+T
Sbjct 734 REYHYGNNFGYIVAFKPFDGEEWK-----------KVTVTNPDTGRYVHKDETMTPSTAF 782
Query 402 ---VRNLVGKSDA-----AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKY 453
V+ K D AV+ A D + P + + V W K+
Sbjct 783 QVKVKAFNNKGDGPYSLVAVIN-SAQDAPSEAPTEVGVKVLSSSEISVHW--------KH 833
Query 454 ILEWCVLSDKAPCITDWQQED--GTVHRTYLRG--------NLAESKCYLITVTPVYADG 503
+LE V S + I W D HR + NL Y I V + G
Sbjct 834 VLEKIVESYQ---IRYWAGHDKEAAAHRVQVTSQEYSARLENLLPDTQYFIEVGACNSAG 890
Query 504 PG-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII 562
G S + I+ + ++APPS+ P + + + ++ WD + + Y I YR
Sbjct 891 CGPSSDVIETFTRKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKILYRP-- 948
Query 563 GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ + S+H + D Y+V + A++D G
Sbjct 949 DGQHDGKLFSTHKHSIEVPIPRDGEYVVEVRAHSDGG 985
>sp|O13146|EPHA3_DANRE Ephrin type-A receptor 3 OS=Danio rerio
OX=7955 GN=epha3 PE=1 SV=1
Length=981
Score = 40.8 bits (94), Expect = 0.065, Method: Compositional matrix adjust.
Identities = 49/205 (24%), Positives = 80/205 (39%), Gaps = 29/205 (14%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
PP P N +VNE + EW R++ + + ++ H C + C
Sbjct 328 PPSAPGNPISMVNE-TAVTLEWSPPRDSGGRGDVS----YSVH-CRKCSGETGASERCVP 381
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINF-------DPVYKVKPNPPH--NLSVINSEE 235
S +F + + L H N+ + V + P+P +++V S+
Sbjct 382 CGSGAHFNPRQFGLTHPRVLVTELQPHTNYTFSVEALNGVSDLSPSPRQLVSVNVTTSQT 441
Query 236 LSSILK---------LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS-SFT 285
+S ILK L W P +++Y + Y K+ Q T+S S T
Sbjct 442 VSVILKERKGTDSVTLAWQGPEPVDGTVVEYEVTYYEKN----QQDQNYTVLKTKSNSMT 497
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYW 310
V LKP T Y+FR+R + G G +
Sbjct 498 VDGLKPGTTYIFRVRARTDGGYGNY 522
>sp|A0MSX9|IL7RA_HORSE Interleukin-7 receptor subunit alpha OS=Equus
caballus OX=9796 GN=IL7R PE=2 SV=1
Length=458
Score = 40.4 bits (93), Expect = 0.065, Method: Compositional matrix adjust.
Identities = 33/130 (25%), Positives = 62/130 (48%), Gaps = 10/130 (8%)
Query 206 KVTSDHI---NFDPVYKVKPNPPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYNIQY 261
K+ HI + V +VKP P ++ VI EE + ++ ++ K V L + + Y
Sbjct 110 KLGGKHITCQKLNIVKRVKPEAPFDVKVIYREEANEFVVTFNTSHLQKKYVKDLLHEVVY 169
Query 262 RT-KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG--KGYWSDWSEEAS 318
R K+ + W + + +ST+ + + L+P Y ++R + +G+WS+WS +
Sbjct 170 RLEKNENDWMHV---NISSTKLTLLQRKLQPNAMYEIKVRSIPNTNYFEGFWSEWSPSSH 226
Query 319 GITYEDRPSK 328
T E+ K
Sbjct 227 FRTPENNSGK 236
Score = 37.4 bits (85), Expect = 0.66, Method: Compositional matrix adjust.
Identities = 40/198 (20%), Positives = 90/198 (45%), Gaps = 21/198 (11%)
Query 546 VQNGFIRN--YTIFYRTIIGNETAVNVDSSHTEYTL--SSLTSDTLYMVRMAAYTDEGGK 601
+Q ++++ + + YR ++V+ S T+ TL L + +Y +++ + +
Sbjct 155 LQKKYVKDLLHEVVYRLEKNENDWMHVNISSTKLTLLQRKLQPNAMYEIKVRSIPNTNYF 214
Query 602 DG------PEFTFTTPKFAQGEIEAIVVPVCL-AFLLTTLLGVLFCFNKRDLIKKHIWPN 654
+G P F TP+ G+++ +++ + + +F L+ +L C + IK +WP+
Sbjct 215 EGFWSEWSPSSHFRTPENNSGKMDPVLLIISIVSFFSVALMVILACVLWKKRIKPIVWPS 274
Query 655 VPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEA----NDKKPFPEDLKS 710
+PD K+ + Q P+ N N ++ +F D + +++ ++ + F +D
Sbjct 275 LPDHKKT-LEQLCKK--PKKNLNVS---FNPESFLDCQIHKVDGIQARDEAEAFLQDTFP 328
Query 711 LDLFKKEKINTEGHSSGI 728
L EK G G+
Sbjct 329 PQLDDSEKQRLGGGVQGL 346
>sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mus
musculus OX=10090 GN=Tie1 PE=1 SV=3
Length=1134
Score = 40.8 bits (94), Expect = 0.069, Method: Compositional matrix adjust.
Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 15/112 (13%)
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST-- 268
H++ P P H ++ +SE ++L W +P S I KY ++ + S
Sbjct 632 HVHLPPSGPPAPRHLHAQALSDSE-----IQLMWQHPEAPSGPISKYIVEIQVAGGSGDP 686
Query 269 -WSQIP-PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
W + PE+T S V+ L T Y+FR+R + G G WS+ EEA+
Sbjct 687 QWMDVDRPEET-----SIIVRGLNASTRYLFRVRASVQ-GLGDWSNTVEEAT 732
>sp|Q91145|COCA1_NOTVI Collagen alpha-1(XII) chain (Fragment)
OS=Notophthalmus viridescens OX=8316 PE=2 SV=1
Length=929
Score = 40.8 bits (94), Expect = 0.069, Method: Compositional matrix adjust.
Identities = 121/515 (23%), Positives = 181/515 (35%), Gaps = 49/515 (10%)
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
F ++ +LT +I + ++EQ + I + S PP ++LS R W
Sbjct 35 FDAFQRISFELTQSI--WLRIEQELKSIKVKSLTPP---RDLSFAEVTSSSFRVSWSPAA 89
Query 151 ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD 210
E + +F PT+ TV + EV V AE G+ S
Sbjct 90 EDAIAYLVNYTVALGGEEFV---VSVPAPTTSTVLTNLFPKTTYEVRVVAEYPEGE--SP 144
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS 270
+ + P NL V ++E + K+ WT P+ +V L+Y I YR
Sbjct 145 PLKGEETTLEVRGAPRNLRV--TDETTDSFKVGWT-PAPGNV--LRYRIAYRPVAGGERK 199
Query 271 QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
++ + T+ +L P T+Y + + E Y S +G + P
Sbjct 200 EV---TVQGNERATTLYNLFPDTKY--HVSGVPE----YQSGPGTALNGNGATEEVVGEP 250
Query 331 SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS--HLQNYTVNA-TKL 387
+P+ + R L W P GK+ Y L + ++ TV T
Sbjct 251 KNLRVSEPTTSTAMR---LTWDKAP-----GKVQRYLRNLHSRSAGGDIKEVTVKGDTST 302
Query 388 TVNLTNDRYLA-TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTT 445
TV D A TL+V L +T Q DL D + WT
Sbjct 303 TVLKELDPGTAYTLSVNPLYASGAGTAVTGEGATLQERGSPRDLIIKDITDTTIGTSWTA 362
Query 446 PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
V+ Y + W L D T G T LR NL Y ++V YA G G
Sbjct 363 APGMVRGYRIAWQSLFDDK---TGENHVPGDTTNTVLR-NLDPETKYRLSVYANYASGEG 418
Query 506 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE 565
P S +A + +P G V+ + + W P G + NY + YR G
Sbjct 419 DPLSGEATTEASP--DGKIVKISEETETTMKATWQPAP-----GNVLNYRVVYRPRAGGR 471
Query 566 TAV-NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
V V + T L LT T Y + + EG
Sbjct 472 QIVAKVPPAVTSTVLRRLTPLTTYDISVIPVYKEG 506
>sp|Q4KMG0|CDON_HUMAN Cell adhesion molecule-related/down-regulated
by oncogenes OS=Homo sapiens OX=9606 GN=CDON PE=1 SV=2
Length=1287
Score = 40.8 bits (94), Expect = 0.072, Method: Compositional matrix adjust.
Identities = 40/173 (23%), Positives = 68/173 (39%), Gaps = 15/173 (9%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A N G V +D V P P ++ + E S + +TW + I + +
Sbjct 703 ANNNFGVVLTDSSRHSGV----PEAPDRPTISTASETS--VYVTWIPRANGGSPITAFKV 756
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+Y+ S W + ED ++ S V+ L+P + Y FR+ + G+ + S S
Sbjct 757 EYKRMRTSNW-LVAAEDIPPSKLSVEVRSLEPGSTYKFRVIAINHYGESFRSSASRPYQV 815
Query 320 ITYED----RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
+ + + RP P Y S TQ + L W +P N I + +
Sbjct 816 VGFPNRFSSRPITGPHIAYTEAVSDTQ----IMLKWTYIPSSNNNTPIQGFYI 864
>sp|Q6PDN3|MYLK_MOUSE Myosin light chain kinase, smooth muscle
OS=Mus musculus OX=10090 GN=Mylk PE=1 SV=3
Length=1941
Score = 40.8 bits (94), Expect = 0.076, Method: Compositional matrix adjust.
Identities = 39/117 (33%), Positives = 54/117 (46%), Gaps = 11/117 (9%)
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNI 259
EN LG + +N V K P+PP + S+ SS L L+W S + YN+
Sbjct 1335 ENKLGSRQA-QVNLTVVDK--PDPPAG-TPCASDIRSSSLTLSWYGSSYDGGSAVQSYNV 1390
Query 260 QYRTKDASTWSQIPPEDTASTRS-SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+ + W ++ A+ RS SF VQDL P EY FR+R + G S SE
Sbjct 1391 EIWDTEDKVWKEL-----ATCRSTSFNVQDLLPDREYKFRVRAVNVYGTSEPSQESE 1442
>sp|O09030|I13R1_MOUSE Interleukin-13 receptor subunit alpha-1
OS=Mus musculus OX=10090 GN=Il13ra1 PE=2 SV=1
Length=424
Score = 40.0 bits (92), Expect = 0.082, Method: Compositional matrix adjust.
Identities = 50/215 (23%), Positives = 82/215 (38%), Gaps = 22/215 (10%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWAT-HKFADCKA--KRDTP 179
G P L CI + M+C W GR T +T++TL +++ K C+ +
Sbjct 121 GDPESAVTELKCIWHNLSYMKCSWLPGRNTSPDTHYTLYYWYSSLEKSRQCENIYREGQH 180
Query 180 TSCTVDYSTV--YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
+C+ + V F + V + ++ GK+ VKP+PPH ++ +
Sbjct 181 IACSFKLTKVEPSFEHQNVQIMVKDNAGKIRPSCKIVSLTSYVKPDPPHIKHLLLK---N 237
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPED-----TASTR-----SSFTVQ 287
L + W NP L Y ++ + + E+ + S R S F +
Sbjct 238 GALLVQWKNPQNFRSRCLTYEVEVNNTQTDRHNILEVEEDKCQNSESDRNMEGTSCFQLP 297
Query 288 DLKPFTEYVFRIRCMKE----DGKGYWSDWSEEAS 318
+ Y R+R D WSDWSE S
Sbjct 298 GVLADAVYTVRVRVKTNKLCFDDNKLWSDWSEAQS 332
>sp|P54763|EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus musculus
OX=10090 GN=Ephb2 PE=1 SV=3
Length=986
Score = 40.4 bits (93), Expect = 0.082, Method: Compositional matrix adjust.
Identities = 55/211 (26%), Positives = 84/211 (40%), Gaps = 40/211 (19%)
Query 126 PEKPKNLSCIVNEGKKMRCEW-----DGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
P P+ + VNE M EW GGRE L N KS C + R T
Sbjct 325 PSAPQAVISSVNETSLM-LEWTPPRDSGGRE-DLVYNIICKS---------CGSGRGACT 373
Query 181 SC--TVDYS---------TVYFVNIEVWVEAENALGKV--TSDHINFDPVYK-----VKP 222
C V Y+ +Y ++ + + V +D F P +
Sbjct 374 RCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQ 433
Query 223 NPPHNLSVIN--SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P +S+++ S + SI L+W+ P + +IL Y +QY K+ S ++ S
Sbjct 434 AAPSAVSIMHQVSRTVDSI-TLSWSQPDQPNGVILDYELQYYEKELSEYNATA---IKSP 489
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
++ TVQ LK YVF++R G G +S
Sbjct 490 TNTVTVQGLKAGAIYVFQVRARTVAGYGRYS 520
>sp|Q90478|L1CA1_DANRE Neural cell adhesion molecule L1.1 (Fragment)
OS=Danio rerio OX=7955 GN=nadl1.1 PE=2 SV=1
Length=1197
Score = 40.4 bits (93), Expect = 0.085, Method: Compositional matrix adjust.
Identities = 100/471 (21%), Positives = 192/471 (41%), Gaps = 71/471 (15%)
Query 189 VYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
+Y + ++++ A G +T + KP+PP +L + SE++ + ++W
Sbjct 522 IYSCEVSTTLDSDTASGYIT---------VQDKPDPPQSLKL--SEKMERSVTISWMPSV 570
Query 249 IKSVIILKYNIQY---RTKDASTWSQIPP--EDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
+ + +Y I+ T D W + +D S RS + +++Y F+IR +
Sbjct 571 ENNSPVTEYVIEMNEGETPDEGQWQKYRSVSQDIDSWRS------ICSYSKYHFQIRAVN 624
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPS--FWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
G ++ S S T +P P DP +++ + W+ + + NG
Sbjct 625 SIGTSAPTESSLSYS--TPAAKPDTNPENVMTLSTDP------KSMIISWQEMDRRQFNG 676
Query 362 KILDYEVTLTRWK---SHLQNYTVNATKLTVNLTNDRYLATLTVR--NLVGKSDAAVLTI 416
Y+V R +H +V+ L VN T + V+ N +G + + I
Sbjct 677 PGFQYKVFWRRAADSGAHWTESSVSNPPLMVNNTGTFVSFEIKVQAVNDLGAAPEPLTVI 736
Query 417 --PACDFQATHP-VMDLKAFPKDNMLWVEWTTPR-ESVKKYILEWCV-LSDKAPCITDWQ 471
DF P + + K +++ V W+ R ESV+ ++L + + L K + W+
Sbjct 737 GYSGEDFPLEAPSALSVTELQKTSVM-VRWSPVRPESVRGHLLGYKIYLRMKG---SQWE 792
Query 472 QEDGTVHRT--------------YLRGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQ 516
V + + +L Y +T+T + G G P S +++ +
Sbjct 793 TPGRAVSSSGNPTVIEVPADAAEKIVSDLQFYSDYTLTITAFNSKGEG-PHSEESFSTPE 851
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR-TIIGNETAVNVDS--- 572
P + ++E L W+ NG IR Y + Y+ +IG+E+ +V+S
Sbjct 852 GAPGPVLFLPFDSPSESEITLRWEA--PHKPNGEIRGYLLQYQEVVIGSESPQHVESIDL 909
Query 573 -SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIV 622
+ TE+TL +L ++ Y ++A D G DG + GE +++
Sbjct 910 PAVTEFTLKNLNPESRYTFHLSARNDAG--DGAPAIQSGATLLDGEPPSVI 958
>sp|Q90W79|CNTN5_CHICK Contactin-5 OS=Gallus gallus OX=9031 GN=CNTN5
PE=1 SV=1
Length=1027
Score = 40.4 bits (93), Expect = 0.089, Method: Compositional matrix adjust.
Identities = 92/421 (22%), Positives = 168/421 (40%), Gaps = 44/421 (10%)
Query 223 NPPHNLSVINSEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP--PEDTAS 279
PP V+ EE++ + L+W+ + I YN+Q R+ + W + P+ +
Sbjct 596 GPPGPPGVVIVEEITDTTATLSWSPGADNHSPISLYNLQARSPFSLGWQTVKTVPDVISG 655
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI-TYEDRPSKAPSFWYKIDP 338
S +L P+ EY FR+ + G G D S + I T E P P+ +
Sbjct 656 DMESAMAVELNPWVEYEFRVVATNKIGTG---DPSAPSRMIRTNEAVPKTPPA-----NV 707
Query 339 SHTQGYR-TVQLVWKTLPPFEANGKILDYEVTL----TR-WKSHLQNYTVNATKLTVNLT 392
S G R + + W+ + NG+ Y V TR WK + V ++ + +
Sbjct 708 SGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKM----VTSSDASKFIY 763
Query 393 NDRYLATLT-------VRNLVGKSD-AAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEW 443
D + LT V N G + ++ I + + + T +D+KA + + V W
Sbjct 764 RDESVPPLTPFEVKVGVYNNKGDGPFSPIVVICSAEGEPTAAPIDVKATSLSVSEILVAW 823
Query 444 TTPRESVKK----YILEWCVL-SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
+ES+ + I W + ++A + ++ T L GN Y +TV
Sbjct 824 KHIKESLGRPQGFEIGYWKDMEQEEAAEKVKTAGNESSLLLTGLEGN----TLYHLTVRA 879
Query 499 VYADGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
A G G P +++ K++PPS+ P+ + L W+ + + Y +
Sbjct 880 YNAAGYGPPSTAVRVATKKSPPSQAPSNVMWIQDGSHVSLGWEPVRPLANESEVMGYKVL 939
Query 558 YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
R G + +++ T + L +Y++ + A + EGG P +A G+
Sbjct 940 LRQ-EGQSNSQVIETQKTSAVV-ILPDVGVYIIEVCAVS-EGGDGTASPQIRVPSYAGGK 996
Query 618 I 618
+
Sbjct 997 V 997
>sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens
OX=9606 GN=EPHB2 PE=1 SV=5
Length=1055
Score = 40.4 bits (93), Expect = 0.091, Method: Compositional matrix adjust.
Identities = 55/211 (26%), Positives = 84/211 (40%), Gaps = 40/211 (19%)
Query 126 PEKPKNLSCIVNEGKKMRCEW-----DGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
P P+ + VNE M EW GGRE L N KS C + R T
Sbjct 325 PSAPQAVISSVNETSLM-LEWTPPRDSGGRE-DLVYNIICKS---------CGSGRGACT 373
Query 181 SC--TVDYS---------TVYFVNIEVWVEAENALGKV--TSDHINFDPVYK-----VKP 222
C V Y+ +Y ++ + + V +D F P +
Sbjct 374 RCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQ 433
Query 223 NPPHNLSVIN--SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P +S+++ S + SI L+W+ P + +IL Y +QY K+ S ++ S
Sbjct 434 AAPSAVSIMHQVSRTVDSI-TLSWSQPDQPNGVILDYELQYYEKELSEYNATA---IKSP 489
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
++ TVQ LK YVF++R G G +S
Sbjct 490 TNTVTVQGLKAGAIYVFQVRARTVAGYGRYS 520
Score = 34.3 bits (77), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 55/234 (24%), Positives = 92/234 (39%), Gaps = 29/234 (12%)
Query 439 LWVEWTTPRESVKKYILEWCVL-----SDKAPCITDW-------QQEDGTVHRTYLRGNL 486
L +EWT PR+S + L + ++ S + C +Q T R Y+ L
Sbjct 340 LMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLL 399
Query 487 AESK--CYLITVTPVYADGPGSPE--SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
A ++ + V V P SP+ S+ QA PS + + L W Q
Sbjct 400 AHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQ- 458
Query 543 PVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-G 600
D NG I +Y + +Y + A + S T+ L + +Y+ ++ A T G G
Sbjct 459 -PDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYG 517
Query 601 KDGPEFTFTTPKFA------QGEIEAIV--VPVCLAFLLTTLLGVLFCFNKRDL 646
+ + F T A Q ++ I+ L FL+ ++ + C N+R
Sbjct 518 RYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSAAGLVFLIAVVVIAIVC-NRRGF 570
>sp|Q91694|EPA4B_XENLA Ephrin type-A receptor 4-B OS=Xenopus laevis
OX=8355 GN=epha4-b PE=2 SV=1
Length=985
Score = 40.4 bits (93), Expect = 0.096, Method: Compositional matrix adjust.
Identities = 53/214 (25%), Positives = 81/214 (38%), Gaps = 44/214 (21%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAKRDTP 179
PP P+NL VNE + EW GGR + ++ L + C +P
Sbjct 328 PPSAPQNLISNVNE-TSVNLEWSPPQNSGGRP---DVSYNLVCKRCGSDLTRC-----SP 378
Query 180 TSCTVDYS--------TVYFVN---------IEVWVEAENALGKVTSDHINFDPVYKV-- 220
V YS T +N EVW A+ V+ + D V
Sbjct 379 CGSGVHYSPQQNGLKTTKVSINDLQAHTNYTFEVW-----AINGVSKQNPEQDQAVSVTV 433
Query 221 --KPNPPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
P ++ I +E++ + LTW P + +IL+Y ++Y KD + S
Sbjct 434 TTNQAAPSTVTQIQPKEITRHSVSLTWPEPERANGVILEYEVKYYEKDQNERSY---RIV 490
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+ S ++ L P T YVF +R G G +S
Sbjct 491 KTASRSADIKGLNPLTGYVFHVRARTAAGYGEFS 524
>sp|Q15746|MYLK_HUMAN Myosin light chain kinase, smooth muscle
OS=Homo sapiens OX=9606 GN=MYLK PE=1 SV=4
Length=1914
Score = 40.4 bits (93), Expect = 0.098, Method: Compositional matrix adjust.
Identities = 42/128 (33%), Positives = 61/128 (48%), Gaps = 14/128 (11%)
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNI 259
EN LG + +N V K P+PP + S+ SS L L+W S + Y+I
Sbjct 1313 ENKLGSRQA-QVNLTVVDK--PDPPAG-TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
Query 260 QYRTKDASTWSQIPPEDTASTRS-SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+ TW ++ A+ RS SF VQDL P EY FR+R + G S+ S+E+
Sbjct 1369 EIWDSANKTWKEL-----ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT---SEPSQESE 1420
Query 319 GITYEDRP 326
T ++P
Sbjct 1421 LTTVGEKP 1428
>sp|P29319|EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus musculus
OX=10090 GN=Epha3 PE=1 SV=1
Length=983
Score = 40.4 bits (93), Expect = 0.098, Method: Compositional matrix adjust.
Identities = 32/97 (33%), Positives = 48/97 (49%), Gaps = 4/97 (4%)
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV-DSSH 574
QA PS T++ + +N L W Q P + NG I +Y + Y ET+ + +
Sbjct 433 QAAPSPVMTIKKDRTSRNSISLSW-QEP-EHPNGIILDYEVKYYQKQEQETSYTILRARG 490
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTT 610
T T+SSL DT Y+ ++ A T G G + +F F T
Sbjct 491 TNVTISSLKPDTTYVFQIRARTAAGYGTNSRKFEFET 527
Score = 38.5 bits (88), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 46/200 (23%), Positives = 78/200 (39%), Gaps = 22/200 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAK-RDT 178
PP P+N+ +NE + +W GGR+ K W + C R
Sbjct 324 PPSAPRNVISNINETSVI-LDWSWPLDTGGRKDITFNIICKKCGWNVRQCEPCSPNVRFL 382
Query 179 PTSCTVDYSTVYFV------NIEVWVEAENALGKVTSDHINFDPVY----KVKPNPPHNL 228
P + +TV N ++A N + +++S + V + P+P +
Sbjct 383 PRQLGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQYAAVSITTNQAAPSPV--M 440
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
++ + + L+W P + IIL Y ++Y K S + ++ T+
Sbjct 441 TIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYQKQEQETSYTI---LRARGTNVTISS 497
Query 289 LKPFTEYVFRIRCMKEDGKG 308
LKP T YVF+IR G G
Sbjct 498 LKPDTTYVFQIRARTAAGYG 517
>sp|Q2KL21|EPOR_CANLF Erythropoietin receptor OS=Canis lupus familiaris
OX=9615 GN=EPOR PE=2 SV=1
Length=508
Score = 40.0 bits (92), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 48/214 (22%), Positives = 83/214 (39%), Gaps = 21/214 (10%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHL-ETNFTLKSEWATHKFADCKAKRDTPTSC 182
L P+ L C + + C W+ + N++ + + C + T
Sbjct 42 LAARAPEELLCFTERLEDLVCFWEEAASAGVGPDNYSFFYQLEGEPWKTCSLHQAPTTRG 101
Query 183 TVDY-------STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
V + T FV +E+ A ++ + I+ + V + +PP L ++E
Sbjct 102 AVRFWCSLPTADTSSFVPLELRATAVSSGALLYRRIIHINEVVLL--DPPAGLLARRADE 159
Query 236 LSSILKLTWTNPS---IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
++ L W P + S+I + NI S +I R+ + +L+
Sbjct 160 GGHVV-LRWLPPPGAPVASLIRYEVNISGSVAGGSQKVEI-----LDGRTECVLSNLRGG 213
Query 293 TEYVFRIRC-MKEDG-KGYWSDWSEEASGITYED 324
T Y F +R M E G+WS WSE AS +T D
Sbjct 214 TRYTFMVRARMAEPSFGGFWSAWSEPASLLTASD 247
>sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens
OX=9606 GN=EPHA2 PE=1 SV=2
Length=976
Score = 40.0 bits (92), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 53/205 (26%), Positives = 84/205 (41%), Gaps = 23/205 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW-----DGGRETHLETNFTLKSEW-ATHKFADCKAK--- 175
PP P L+ V G K+ W GGRE + + T + W + + C+A
Sbjct 328 PPSAPHYLTA-VGMGAKVELRWTPPQDSGGRE-DIVYSVTCEQCWPESGECGPCEASVRY 385
Query 176 RDTPTSCTVDYSTVY----FVNIEVWVEAENAL-GKVTSDHINFDPVYKVKPNPPHNLSV 230
+ P T TV +N VEA N + G VTS V + PP V
Sbjct 386 SEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSFRTASVSINQTEPP---KV 442
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
++ L ++W+ P + + KY + YR K S + + S T+ DL
Sbjct 443 RLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNSYNV----RRTEGFSVTLDDLA 498
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSE 315
P T Y+ +++ + ++G+G S E
Sbjct 499 PDTTYLVQVQALTQEGQGAGSKVHE 523
>sp|Q60847|COCA1_MOUSE Collagen alpha-1(XII) chain OS=Mus musculus
OX=10090 GN=Col12a1 PE=2 SV=3
Length=3120
Score = 40.4 bits (93), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 38/119 (32%), Positives = 51/119 (43%), Gaps = 13/119 (11%)
Query 485 NLAESKCYLITVTPVYADG---PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
NL YL+ VT Y DG P + E A +K P + T T K L W Q
Sbjct 690 NLRPETLYLVNVTAEYEDGFSVPITGEETTAEVKGVPRNLKVTDETTDSFK----LTWSQ 745
Query 542 LPVDVQNGFIRNYTIFYRTIIGNETA-VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
P G + Y I YR + G E+ V+ ++ TL +LT DT Y + + A G
Sbjct 746 AP-----GRVLRYRIRYRPVSGGESKEVSTPANQRRKTLENLTPDTKYEISVIAEYSSG 799
Score = 38.5 bits (88), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 87/396 (22%), Positives = 149/396 (38%), Gaps = 67/396 (17%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP +L ++ ++ K W+ P + Y++ Y KDA+ ++ + AS+ +S
Sbjct 634 PPKDLRF--TQVTANSFKAEWSPPGDN---VFSYHVTY--KDANGDDEVTVVEPASS-TS 685
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+ +L+P T Y+ + EDG E + + K K+ T
Sbjct 686 VVLNNLRPETLYLVNVTAEYEDGFSVPITGEETTAEV-------KGVPRNLKVTDETTDS 738
Query 344 YRTVQLVWKTLPPFEANGKILDYEVT---LTRWKSHLQNYTVNATKLTV-NLTND-RYLA 398
++ L W P G++L Y + ++ +S + N + T+ NLT D +Y
Sbjct 739 FK---LTWSQAP-----GRVLRYRIRYRPVSGGESKEVSTPANQRRKTLENLTPDTKYEI 790
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD--------NMLWVEWTTPRESV 450
++ G P +++ P+D + L + W+ V
Sbjct 791 SVIAEYSSG---------PGSPLTGNAATEEVRGNPRDLRVSDATTSTLKLSWSRAPGKV 841
Query 451 KKYILEWCVLSDKAPCITDWQQE---DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
K+Y++ + P QE G T LR L E Y ++VT +YA G G
Sbjct 842 KQYLVTYT------PAAGGETQEVTVRGDTTTTMLR-KLKEGTQYDLSVTALYASGAGEA 894
Query 508 ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI----FYRTIIG 563
S K + S V TK + W P G +R Y + Y I
Sbjct 895 LSGKGSTLEERGSPQNLV-TKDITDTSIGAYWTSAP-----GMVRGYRVSWKSLYDDIEA 948
Query 564 NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
ET + D+ HT + +L +T Y + + A G
Sbjct 949 GETTLPGDAIHT--MIENLQPETKYKISVFATYSSG 982
Score = 36.2 bits (82), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 72/308 (23%), Positives = 126/308 (41%), Gaps = 53/308 (17%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P NL + SE +++WT PS + +Y ++Y + + +S
Sbjct 1388 PTNLVI--SERTHRSFRVSWTPPSDS---VDRYKVEYYPVSGGKRQEF---YVSRLDTST 1439
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF-WYKIDPSHTQG 343
++DLKP T+YV + + ED ++SE G T + P S Y + P+
Sbjct 1440 VLKDLKPETDYVVNVYSVVED------EYSEPLKG-TEKTLPVPVVSLNIYDVGPT---- 1488
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTL----TRWKSHLQNYTVNATKLTVNLTNDRYLAT 399
T+ + W+ P A G + Y+ T T+ K TVN +LT L N Y T
Sbjct 1489 --TMHVQWQ--PVGGATGYTVSYQPTRSPEGTKPKEMRVGPTVNDVQLTGLLPNTEYEVT 1544
Query 400 L--TVRNLVGK-SDAAVLTIPACDFQ------ATHPVMDLKAFPKDNMLWVEWTTPRESV 450
+ + +L + + A +T+P Q TH M+ V W V
Sbjct 1545 VQAVLYDLTSEPAKAREVTLPLPRPQDVKLRDVTHSTMN-----------VVWEPVLGKV 1593
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
+KYI+ + ++ + + D + T L+ +L+ Y ++V+ VY +G P +
Sbjct 1594 RKYIVRYKTPDEEFKEV----EVDRSRASTILK-DLSSQTQYTVSVSAVYDEGTSPPATA 1648
Query 511 KAYLKQAP 518
++ P
Sbjct 1649 YDTTRRVP 1656
Score = 35.0 bits (79), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 49/191 (26%), Positives = 76/191 (40%), Gaps = 17/191 (9%)
Query 427 VMDLKAF-PKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
V +L+ + P + L V W + ++Y L + S + G + LR N
Sbjct 1849 VRNLRVYDPSTSSLSVRWDHAEGNPRQYKLFYAPTSGGPEELVPIP---GNTNYAILR-N 1904
Query 486 LAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
L Y ITV PVY +G G S ++ ++ N + WD P
Sbjct 1905 LQPDTPYTITVVPVYTEGDGGRTSDTGRTLVRGLAR--NIQVYNPTPNSLDVRWDPAP-- 1960
Query 546 VQNGFIRNYTIFYRTIIG---NETAVNVDSSHTEYTLSSLTSDTLYMVRMAA-YTDEGGK 601
G ++ Y I Y + G +E+ V ++ T + L L DT Y V + A Y+D G
Sbjct 1961 ---GPVQQYRIVYSPVAGTRPSESIVVPGNTRTVH-LERLIPDTPYSVNIVALYSDGEGN 2016
Query 602 DGPEFTFTTPK 612
P T P+
Sbjct 2017 PSPSQGRTLPR 2027
>sp|P0DSP1|SORL_RAT Sortilin-related receptor OS=Rattus norvegicus
OX=10116 GN=Sorl1 PE=1 SV=1
Length=2215
Score = 40.0 bits (92), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 56/218 (26%), Positives = 94/218 (43%), Gaps = 31/218 (14%)
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD 265
K SD + VYKV+ NL I + S + LTWT P YN+ YR
Sbjct 1547 KACSDELT---VYKVQ-----NLQWI--ADFSGDVTLTWTRPKKMPSASCVYNVYYRVVG 1596
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR--CMKEDGKGYWSDWSEEASGITYE 323
S W + +T S ++S ++ LKP T Y +++ C+ + + ++ + T E
Sbjct 1597 ESIWKTL---ETHSNKTSTVLKVLKPDTTYQVKVQVHCLSK-----VHNTNDFVTLRTPE 1648
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL---QNY 380
P + ++ S +G ++ PP +G I +Y V +R S + Q
Sbjct 1649 GLPDAPRNLQLSLN-SEEEGV----ILGHWAPPVHTHGLIREYIVEYSRSGSKMWASQRA 1703
Query 381 TVNATKLTVNLTNDRY---LATLTVRNLVGKSDAAVLT 415
N+T++ L N Y +A +T R + SD+ +T
Sbjct 1704 ASNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSIT 1741
Score = 39.3 bits (90), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 90/390 (23%), Positives = 142/390 (36%), Gaps = 56/390 (14%)
Query 222 PNPPHNLSV-INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P+ P NL + +NSEE IL W P +I +Y ++Y + W+ +
Sbjct 1651 PDAPRNLQLSLNSEEEGVILG-HWAPPVHTHGLIREYIVEYSRSGSKMWAS-----QRAA 1704
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE---------EASGITYEDRPSKAPS 331
+S +++L Y R+ + G G WSD +A I + + S
Sbjct 1705 SNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSITTTKGKVIQAPNIHIDSYDENSLS 1764
Query 332 FWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL 391
F +D V L W + + K L++ R S L + N T T
Sbjct 1765 FTLTMDGDIKVNGYVVNLFW-SFDAHKQEKKTLNF-----RGGSSLSHKVSNLTAHT--- 1815
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE--WTTPRES 449
Y + + +G S A I P + KA N VE WT P+
Sbjct 1816 ---SYEVSAWAKTDLGDSPLAFEHILTRGISPPAPSLKAKAI---NQTAVECIWTGPKNV 1869
Query 450 VKK--YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
V Y + L +T ++H + + E +L+ V Y P
Sbjct 1870 VYGIFYATSFLDLYRNPKSLTT------SLHNKTVIVSKDEQYLFLVRVLIPYQ----GP 1919
Query 508 ESIKAYLKQAPPSKGP--TVRTKKVGKNEAVLEWDQLPVDV--QNGFIRNYTIFYRTII- 562
S +K P S+ P + ++GK AV++W+ P D Q+ F Y I + +I
Sbjct 1920 SSDYVVVKMIPDSRLPPRHLHAVQIGKTSAVIKWES-PYDSPDQDLF---YAIAVKDLIR 1975
Query 563 --GNETAVNVDSSHTEYTLSSLTSDTLYMV 590
V +S EY+LS L Y +
Sbjct 1976 KTDRSYKVRSRNSTVEYSLSKLEPGGKYHI 2005
>sp|P08941|ROS1_CHICK Proto-oncogene tyrosine-protein kinase ROS
OS=Gallus gallus OX=9031 GN=ROS1 PE=1 SV=3
Length=2311
Score = 40.0 bits (92), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 51/180 (28%), Positives = 77/180 (43%), Gaps = 39/180 (22%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
AE+A G + +N KP P S I S ++ L W +I V KY
Sbjct 95 RAEDAYGVEAQNCLN-------KPGAPF-ASSIGSHNIT----LGWKPANISEV---KYI 139
Query 259 IQYRTKDASTWSQIPPE---DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS---- 311
IQ++ + Q+P + + +S+TV+DL+ FTEY FR+ + S
Sbjct 140 IQWK------FHQLPGDWRYTEVVSETSYTVKDLQAFTEYEFRVVWIITSQLQLHSPPSP 193
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
+ ASG+ P+ AP I + TV++ W PP NG I+ Y + LT
Sbjct 194 SYRTHASGV-----PTTAP----IIKDIQSSSPNTVEVSW--FPPLFPNGLIVGYNLVLT 242
Score = 34.3 bits (77), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 17/45 (38%), Positives = 26/45 (58%), Gaps = 3/45 (7%)
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
T + F V++L FTEY +R + G+G WSE G+T+E+
Sbjct 630 TDTRFAVKNLVSFTEYEMSVRAVSPAGEG---PWSEPFRGMTFEE 671
>sp|Q8VHK6|I13R2_RAT Interleukin-13 receptor subunit alpha-2 OS=Rattus
norvegicus OX=10116 GN=Il13ra2 PE=2 SV=1
Length=385
Score = 39.7 bits (91), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 45/185 (24%), Positives = 73/185 (39%), Gaps = 9/185 (5%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLK--SEWATHKF--ADCKAKRDTPTSCT 183
K +++ CI + + C W G+ H +TN+T+ E H AD + C
Sbjct 135 KIQDMKCIYYNWQYLVCSWKPGKTVHSDTNYTMFFWYEGLDHALQCADYLQDNEKNVGCK 194
Query 184 V-DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
+ + + + + + V + L + S ++ F VKP PP L + S E S +++
Sbjct 195 LSNLDSSDYKDFFIRVNGSSKLEPIRSSYMVFQLQNIVKPLPPEFLHI--SVENSIDIRM 252
Query 243 TWTNPSIK-SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
W+ P Y I R D S S D R + +DL F I C
Sbjct 253 KWSTPGGPIPPSCYTYEIVVREDDISWESATDKNDMKLKRRANESEDLCFFVRCKINIYC 312
Query 302 MKEDG 306
+DG
Sbjct 313 -ADDG 316
>sp|Q4W815|EPOR_XENLA Erythropoietin receptor OS=Xenopus laevis
OX=8355 GN=epor PE=2 SV=1
Length=525
Score = 39.7 bits (91), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 43/204 (21%), Positives = 82/204 (40%), Gaps = 22/204 (11%)
Query 121 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
IS PE+ +N C + C W+G R + +++ + C+ + + +
Sbjct 45 ISEKIPEEYQNPHCFTRDLNDFICFWEGERRKNASFSYS-----EDDQIKWCQLRTEVAS 99
Query 181 SCTVDY-------STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS 233
+ T Y V F I + + +IN V NPP N++V
Sbjct 100 NNTWWYICEFPVTDVVLFAGITISAYPCHKCQTAREIYIN----ELVLLNPPLNVTVKEK 155
Query 234 EELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
++ +L ++W P + + I+Y+ ++ + + + + + + D+ P
Sbjct 156 QDPRGLL-ISWKPPHFQKNHDINNEIKYQVNYSTPGADMQTVEVEAGNTEIFLTDIVP-A 213
Query 294 EYVFRIRCMKEDG---KGYWSDWS 314
Y +RC K DG GYWSDW+
Sbjct 214 AYTVTVRC-KADGVSYNGYWSDWT 236
>sp|Q03137|EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus musculus
OX=10090 GN=Epha4 PE=1 SV=2
Length=986
Score = 40.0 bits (92), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 49/215 (23%), Positives = 82/215 (38%), Gaps = 43/215 (20%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAKRDTP 179
PP P NL VNE + EW GGR+ + N K K P
Sbjct 328 PPSAPLNLISNVNE-TSVNLEWSSPQNTGGRQ-DISYNVVCK-----------KCGAGDP 374
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINF-------DPVYKVKPNP-------- 224
+ C S V++ + ++ H N+ + V K P+P
Sbjct 375 SKCRPCGSGVHYTPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVSKYNPSPDQSVSVTV 434
Query 225 ------PHNLSVINSEELSSI-LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
P +++++ ++E++ + L W P + +IL+Y ++Y KD + S
Sbjct 435 TTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTA 494
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
A ++ L P T YVF +R G G +S+
Sbjct 495 ARNTD---IKGLNPLTSYVFHVRARTAAGYGDFSE 526
>sp|Q78DX7|ROS1_MOUSE Proto-oncogene tyrosine-protein kinase ROS
OS=Mus musculus OX=10090 GN=Ros1 PE=1 SV=1
Length=2340
Score = 40.0 bits (92), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 48/181 (27%), Positives = 76/181 (42%), Gaps = 20/181 (11%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS---TRSSFTVQDLKPFTEYV 296
+ L W +I V KY IQ++ ++Q+P T + ++ S+TV+ L PFTEY+
Sbjct 125 VTLRWNPANISGV---KYIIQWK------YAQLPGSWTFTETVSKLSYTVEPLHPFTEYI 175
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
FR+ + +S S +Y P P I + TV++ W PP
Sbjct 176 FRVVWIFTAQLHLYSPPSP-----SYRTHPYGVPETAPLILNMESWSPDTVEVSWA--PP 228
Query 357 FEANGKILDYEVTLTRWKSHLQNYTVNAT-KLTVNLTNDRYLATLTVRNLVGKSDAAVLT 415
G IL Y + L L + T + + L N Y ++ N VG+ A T
Sbjct 229 HFPGGPILGYNLRLISKNQKLDSGTQRTSFQFYSTLPNTTYRFSIAAVNEVGEGPEAEST 288
Query 416 I 416
+
Sbjct 289 V 289
>sp|Q7ZX59|CRLF3_XENLA Cytokine receptor-like factor 3 OS=Xenopus
laevis OX=8355 GN=crlf3 PE=2 SV=1
Length=436
Score = 39.3 bits (90), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 5/58 (9%)
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
Y +QYR AS + + + S F V + P +Y FR+ C + DG+ WS WS
Sbjct 207 YRLQYRKNTASHFEDV----YVGSESEFIVLQIDPNVDYQFRV-CARGDGRQEWSPWS 259
>sp|Q4ZHG4|FNDC1_HUMAN Fibronectin type III domain-containing
protein 1 OS=Homo sapiens OX=9606 GN=FNDC1 PE=2 SV=4
Length=1894
Score = 40.0 bits (92), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 42/167 (25%), Positives = 67/167 (40%), Gaps = 33/167 (20%)
Query 210 DHINFDPVYKVKPN-----------PPHNLSVINSEELSSILKLTWTNPSIKSVII--LK 256
DH D + ++ PN P N++V+ E S + + W + V+ L
Sbjct 1633 DHFQVDSLDEIIPNDLKKSDLPPQHAPRNITVVAVEGCHSFVIVDWDKATPGDVVTGYLV 1692
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y+ Y + WS AS+ + +++LKP T Y F+++ G G S
Sbjct 1693 YSASYEDFIRNKWST-----QASSVTHLPIENLKPNTRYYFKVQAQNPHGYG---PISPS 1744
Query 317 ASGITYED------RPSKAPSFW----YKIDPSHT--QGYRTVQLVW 351
S +T D RP W +K DPS+T G + V+ W
Sbjct 1745 VSFVTESDNPLLVVRPPGGEPIWIPFAFKHDPSYTDCHGRQYVKRTW 1791
>sp|Q91736|EPB1B_XENLA Ephrin type-B receptor 1-B (Fragment) OS=Xenopus
laevis OX=8355 GN=ephb1-b PE=1 SV=1
Length=902
Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 51/207 (25%), Positives = 80/207 (39%), Gaps = 32/207 (15%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRET--HLETNFTLKSEWATHKFADCKAKRD----TP 179
P P+N+ IVNE + EW RET + N+ + + C D P
Sbjct 241 PSGPRNVISIVNE-TAITLEWHPPRETGGRDDVNYNIICKKCQSDRRGCSHCDDNVDFVP 299
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV---INSEEL 236
+ + V+ N+ WV T + + V P PP ++SV N
Sbjct 300 RQLGLTDTRVFISNL--WVHT-----PYTFEIQAVNGVTNKSPFPPQHVSVNITTNQAAP 352
Query 237 SSI------------LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
SS+ + L+W P + IIL Y I+Y KD ++ +T S
Sbjct 353 SSVPIMHQVKATMKSITLSWPQPEQPNGIILDYEIRYYEKDHHEFNSSLARSQTNTAS-- 410
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWS 311
++ L+P YV ++R G G +S
Sbjct 411 -IEGLRPGVVYVVQVRARTVAGYGKFS 436
>sp|O35158|CDON_RAT Cell adhesion molecule-related/down-regulated
by oncogenes OS=Rattus norvegicus OX=10116 GN=Cdon PE=1
SV=2
Length=1256
Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 47/205 (23%), Positives = 81/205 (40%), Gaps = 16/205 (8%)
Query 169 FADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENA-LGKVTSDHINFDPVYKVKPNPPHN 227
F K K + + + V V EA N+ G V +D V P P
Sbjct 668 FRTSKEKMASSKNTQASFPPVGIPKRPVTSEASNSNFGVVLTDSSRHSGV----PEAPDR 723
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
++ + E S + +TW + I + ++Y+ +S W + ED ++ S V+
Sbjct 724 PTISMASETS--VYVTWIPRANGGSPITAFKVEYKRMKSSDW-LVAAEDIPPSKLSVEVR 780
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSE--EASGI--TYEDRPSKAPSFWYKIDPSHTQG 343
L+P + Y FR+ + G+ + S S + +G + +RP P Y S TQ
Sbjct 781 SLEPGSIYKFRVIVINHYGESFRSSASRPYQVAGFPNRFSNRPITGPHIAYTEAVSDTQ- 839
Query 344 YRTVQLVWKTLPPFEANGKILDYEV 368
+ L W +P N I + +
Sbjct 840 ---IMLKWTYIPSSNNNTPIQGFYI 861
>sp|Q05695|L1CAM_RAT Neural cell adhesion molecule L1 OS=Rattus
norvegicus OX=10116 GN=L1cam PE=1 SV=3
Length=1259
Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 47/196 (24%), Positives = 79/196 (40%), Gaps = 21/196 (11%)
Query 438 MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITV 496
+ W++W P+ +Y ++W L + W+++ TV +L N + Y I V
Sbjct 737 LRWMDWNAPQ---IQYRVQWRPLGKQE----TWKEQ--TVSDPFLVVSNTSTFVPYEIKV 787
Query 497 TPVYADGPG-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVL-EWDQLPVDVQNGFIRNY 554
V G G P+ Y + P P + + + VL W + + G +R Y
Sbjct 788 QAVNNQGKGPEPQVTIGYSGEDYPQVSPELEDITIFNSSTVLVRWRPVDLAQVKGHLRGY 847
Query 555 TIFY--RTIIGNETAVNVDSSH-------TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ Y + + +V SH T LS L + Y V + A+ G E
Sbjct 848 NVTYWWKGSQRKHSKRHVHKSHMVVPANTTSAILSGLRPYSSYHVEVQAFNGRGLGPASE 907
Query 606 FTFTTPKFAQGEIEAI 621
+TF+TP+ G EA+
Sbjct 908 WTFSTPEGVPGHPEAL 923
Score = 33.9 bits (76), Expect = 8.5, Method: Compositional matrix adjust.
Identities = 40/155 (26%), Positives = 67/155 (43%), Gaps = 22/155 (14%)
Query 222 PNPPHNLSVINSEEL-SSILKLTWTNPSIKSVIILKYNIQYRTKDAS-----TWSQIPPE 275
P P +L + + L S + L+W+ + I KY+I++ K+ + + ++P
Sbjct 611 PGPVPHLELSDRHLLKQSQVHLSWSPAEDHNSPIEKYDIEFEDKEMAPEKWFSLGKVPGN 670
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
T++T L P+ Y FR+ + + G G S SE +T E P K P
Sbjct 671 QTSTTLK------LSPYVHYTFRVTAINKYGPGEPSPVSETV--VTPEAAPEKNP----- 717
Query 336 IDPSHTQGYRTVQLV--WKTLPPFEANGKILDYEV 368
+D +G T +V WK L + N + Y V
Sbjct 718 VD-VRGEGNETNNMVITWKPLRWMDWNAPQIQYRV 751
>sp|O14522|PTPRT_HUMAN Receptor-type tyrosine-protein phosphatase
T OS=Homo sapiens OX=9606 GN=PTPRT PE=1 SV=6
Length=1441
Score = 39.7 bits (91), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 41/154 (27%), Positives = 63/154 (41%), Gaps = 17/154 (11%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
DPV+ P N+ +++ + L L W YN+ + + Q
Sbjct 385 DPVHG-----PQNVEIVDIR--ARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQYEA 437
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
E+ T S +T++ L+PF R+R + + +G SEE T ED P P
Sbjct 438 EEVIQTSSHYTLRGLRPFM--TIRLRLLLSNPEGRME--SEELVVQTEEDVPGAVPLESI 493
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
+ P + Y + WK PP E NG I YE+
Sbjct 494 QGGPFEEKIY----IQWK--PPNETNGVITLYEI 521
>sp|Q63257|IL4RA_RAT Interleukin-4 receptor subunit alpha OS=Rattus
norvegicus OX=10116 GN=Il4r PE=2 SV=2
Length=801
Score = 39.3 bits (90), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 37/149 (25%), Positives = 60/149 (40%), Gaps = 12/149 (8%)
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEV-WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
C K T C + + + W+E + G++ +F P VKP P NL++
Sbjct 74 CTPKNSADTVCVCQMAIEEPIQADTYWLELWSERGQLWQG--SFKPSDNVKPPAPDNLTL 131
Query 231 INSEELSSILKLTWTNPS-----IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
+ +S+ L L W+NP + +I NI A ++ + SF
Sbjct 132 HTN--VSNALLLMWSNPYPSNNFLHKGLICMVNISREDNPAEF--KVYNVTYTEPKLSFP 187
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
V L Y R+R + + G WS+WS
Sbjct 188 VNTLTSGVRYRARVRVLSQSFPGIWSEWS 216
>sp|Q99M80|PTPRT_MOUSE Receptor-type tyrosine-protein phosphatase
T OS=Mus musculus OX=10090 GN=Ptprt PE=1 SV=2
Length=1454
Score = 39.7 bits (91), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 41/154 (27%), Positives = 63/154 (41%), Gaps = 17/154 (11%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
DPV+ P N+ +++ + L L W YN+ + + Q
Sbjct 389 DPVHG-----PQNVEIVDIR--ARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQYEA 441
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
E+ T S +T++ L+PF R+R + + +G SEE T ED P P
Sbjct 442 EEVIQTSSHYTLRGLRPFM--TIRLRLLLSNPEGRME--SEELVVQTEEDVPGAVPLESI 497
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
+ P + Y + WK PP E NG I YE+
Sbjct 498 QGGPFEEKIY----IQWK--PPNETNGVITLYEI 525
>sp|Q8CBF3|EPHB1_MOUSE Ephrin type-B receptor 1 OS=Mus musculus
OX=10090 GN=Ephb1 PE=1 SV=1
Length=984
Score = 39.3 bits (90), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 54/209 (26%), Positives = 80/209 (38%), Gaps = 36/209 (17%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P P+N+ IVNE + EW RET + T CK R SC+
Sbjct 323 PSGPRNVISIVNE-TSIILEWHPPRETGGRDDVTYN--------IICKKCRADRRSCSRC 373
Query 186 YSTVYFV-------NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV---INSEE 235
V FV V + + A T D + V P PP ++SV N
Sbjct 374 DDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAA 433
Query 236 LSSI------------LKLTWTNPSIKSVIILKYNIQYRTKDASTW-SQIPPEDTASTRS 282
S++ + L+W P + IIL Y I+Y K+ + + S + T + R
Sbjct 434 PSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTAR- 492
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+ L+P YV ++R G G +S
Sbjct 493 ---IDGLRPGMVYVVQVRARTVAGYGKFS 518
>sp|Q91845|EPA4A_XENLA Ephrin type-A receptor 4-A OS=Xenopus laevis
OX=8355 GN=epha4-a PE=2 SV=1
Length=986
Score = 39.3 bits (90), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 22/72 (31%), Positives = 35/72 (49%), Gaps = 3/72 (4%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ LTW P + +IL+Y ++Y KD + + +T S ++ L P T YVF +
Sbjct 456 VSLTWPEPERPNGVILEYEVKYYEKDQNERTY---RIVKTTSRSADIKGLNPLTAYVFHV 512
Query 300 RCMKEDGKGYWS 311
R G G +S
Sbjct 513 RARTAAGYGEFS 524
>sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens
OX=9606 GN=EPHB4 PE=1 SV=2
Length=987
Score = 39.3 bits (90), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 29/113 (26%), Positives = 48/113 (42%), Gaps = 4/113 (4%)
Query 198 VEAENALGKVTSDHINFDPVYKV--KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
V A N + + + + F+PV + PP + + S L L W P S +L
Sbjct 406 VTALNGVSSLATGPVPFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVL 465
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
Y ++Y K A S + T+ R+ ++ LK Y+ ++R E G G
Sbjct 466 DYEVKYHEKGAEGPSSVRFLKTSENRAE--LRGLKRGASYLVQVRARSEAGYG 516
>sp|O08680|EPHA3_RAT Ephrin type-A receptor 3 OS=Rattus norvegicus
OX=10116 GN=Epha3 PE=2 SV=1
Length=984
Score = 39.3 bits (90), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 47/200 (24%), Positives = 78/200 (39%), Gaps = 22/200 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAK-RDT 178
PP P+N+ +NE + +W GGR+ K W + C R
Sbjct 325 PPSAPRNVISNINETSVI-LDWSWPLDTGGRKDITFNIICKKCGWNVRQCEPCSPNVRFL 383
Query 179 PTSCTVDYSTVYFV------NIEVWVEAENALGKVTSDHINFDPVY----KVKPNPPHNL 228
P + +TV N ++A N + +++S F V + P+P +
Sbjct 384 PRQLGLTNTTVTVTDLLAHTNYTFEIDAINGVSELSSPPRQFAAVSITTNQAAPSPV--M 441
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
++ + + L+W P + IIL Y ++Y K S + ++ T+
Sbjct 442 TIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTI---LRARGTNVTISS 498
Query 289 LKPFTEYVFRIRCMKEDGKG 308
LKP T YVF+IR G G
Sbjct 499 LKPDTTYVFQIRARTAAGYG 518
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 31/95 (33%), Positives = 47/95 (49%), Gaps = 4/95 (4%)
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV-DSSH 574
QA PS T++ + +N L W Q P + NG I +Y + Y ET+ + +
Sbjct 434 QAAPSPVMTIKKDRTSRNSISLSW-QEP-EHPNGIILDYEVKYYEKQEQETSYTILRARG 491
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTF 608
T T+SSL DT Y+ ++ A T G G + +F F
Sbjct 492 TNVTISSLKPDTTYVFQIRARTAAGYGTNSRKFEF 526
>sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 OS=Rattus norvegicus
OX=10116 GN=Ephb1 PE=1 SV=2
Length=984
Score = 39.3 bits (90), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 54/209 (26%), Positives = 80/209 (38%), Gaps = 36/209 (17%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P P+N+ IVNE + EW RET + T CK R SC+
Sbjct 323 PSGPRNVISIVNE-TSIILEWHPPRETGGRDDVTYN--------IICKKCRADRRSCSRC 373
Query 186 YSTVYFV-------NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV---INSEE 235
V FV V + + A T D + V P PP ++SV N
Sbjct 374 DDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAA 433
Query 236 LSSI------------LKLTWTNPSIKSVIILKYNIQYRTKDASTW-SQIPPEDTASTRS 282
S++ + L+W P + IIL Y I+Y K+ + + S + T + R
Sbjct 434 PSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTAR- 492
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+ L+P YV ++R G G +S
Sbjct 493 ---IDGLRPGMVYVVQVRARTVAGYGKFS 518
>sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens
OX=9606 GN=EPHB1 PE=1 SV=1
Length=984
Score = 39.3 bits (90), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 54/209 (26%), Positives = 80/209 (38%), Gaps = 36/209 (17%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P P+N+ IVNE + EW RET + T CK R SC+
Sbjct 323 PSGPRNVISIVNE-TSIILEWHPPRETGGRDDVTYN--------IICKKCRADRRSCSRC 373
Query 186 YSTVYFV-------NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV---INSEE 235
V FV V + + A T D + V P PP ++SV N
Sbjct 374 DDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAA 433
Query 236 LSSI------------LKLTWTNPSIKSVIILKYNIQYRTKDASTW-SQIPPEDTASTRS 282
S++ + L+W P + IIL Y I+Y K+ + + S + T + R
Sbjct 434 PSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTAR- 492
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+ L+P YV ++R G G +S
Sbjct 493 ---IDGLRPGMVYVVQVRARTVAGYGKFS 518
>sp|H2A0L8|FND2_PINMG Fibronectin type III domain-containing protein
2 OS=Margaritifera margaritifera OX=102329 PE=1 SV=1
Length=624
Score = 38.9 bits (89), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 25/81 (31%), Positives = 39/81 (48%), Gaps = 3/81 (4%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
PS+ +R N L WD LP+ + G + NYTI+ + G V VD +
Sbjct 238 PSEPTNLRVDGTKPNAIALRWD-LPLLM--GTLANYTIYVTSENGTGFEVAVDPTQVNAI 294
Query 579 LSSLTSDTLYMVRMAAYTDEG 599
L L T Y++ ++A++D G
Sbjct 295 LYDLIEGTRYVISVSAFSDNG 315
>sp|P14753|EPOR_MOUSE Erythropoietin receptor OS=Mus musculus
OX=10090 GN=Epor PE=1 SV=1
Length=507
Score = 38.9 bits (89), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 43/205 (21%), Positives = 77/205 (38%), Gaps = 16/205 (8%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY--- 186
+ L C + + C W+ + ++ N++ + C + +V +
Sbjct 48 EELLCFTQRLEDLVCFWEEAASSGMDFNYSFSYQLEGESRKSCSLHQAPTVRGSVRFWCS 107
Query 187 ----STVYFVNIEVWV-EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
T FV +E+ V EA + HIN V + P L +EE S ++
Sbjct 108 LPTADTSSFVPLELQVTEASGSPRYHRIIHIN----EVVLLDAPAGLLARRAEEGSHVVL 163
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF--RI 299
P ++Y + + + +Q + R+ + +L+ T Y F R
Sbjct 164 RWLPPPGAPMTTHIRYEVDVSAGNRAGGTQR--VEVLEGRTECVLSNLRGGTRYTFAVRA 221
Query 300 RCMKEDGKGYWSDWSEEASGITYED 324
R + G+WS WSE AS +T D
Sbjct 222 RMAEPSFSGFWSAWSEPASLLTASD 246
>sp|Q32MD9|CDON_MOUSE Cell adhesion molecule-related/down-regulated
by oncogenes OS=Mus musculus OX=10090 GN=Cdon PE=1 SV=2
Length=1250
Score = 39.3 bits (90), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 47/205 (23%), Positives = 80/205 (39%), Gaps = 16/205 (8%)
Query 169 FADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENA-LGKVTSDHINFDPVYKVKPNPPHN 227
F K K + + + V V EA N+ G V +D V P P
Sbjct 667 FRTSKEKMASSKNTQASFPPVGVPKRPVTAEASNSNFGVVLTDSSRHSGV----PEAPDR 722
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
++ + E S + +TW + I + ++Y+ S W + ED ++ S V+
Sbjct 723 PTISMASETS--VYVTWIPRANGGSPITAFKVEYKRMRTSDW-LVAAEDIPPSKLSVEVR 779
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSE--EASGI--TYEDRPSKAPSFWYKIDPSHTQG 343
L+P + Y FR+ + G+ + S S + +G + +RP P Y S TQ
Sbjct 780 SLEPGSIYKFRVIAINHYGESFRSSASRPYQVAGFPNRFSNRPITGPHIAYTEAVSDTQ- 838
Query 344 YRTVQLVWKTLPPFEANGKILDYEV 368
+ L W +P N I + +
Sbjct 839 ---IMLKWTYVPSSNNNTPIQGFYI 860
>sp|Q14627|I13R2_HUMAN Interleukin-13 receptor subunit alpha-2
OS=Homo sapiens OX=9606 GN=IL13RA2 PE=1 SV=1
Length=380
Score = 38.5 bits (88), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 44/200 (22%), Positives = 76/200 (38%), Gaps = 11/200 (6%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL--KSEWATHKF--ADCKAKRDT 178
G+P K +++ C+ + + C W G L+TN+ L E H D
Sbjct 134 GIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQ 193
Query 179 PTSCTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
C Y + + + V + + S + F VKP PP L+ + E S
Sbjct 194 NIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTF--TRESS 251
Query 238 SILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
+KL W+ P Y I+ R D + + +T + +++ + L
Sbjct 252 CEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSK 311
Query 297 FRIRCMKEDGKGYWSDWSEE 316
I C + G WS+WS++
Sbjct 312 VNIYCSDD---GIWSEWSDK 328
>sp|Q589G5|PRTG_CHICK Protogenin OS=Gallus gallus OX=9031 GN=PRTG
PE=2 SV=1
Length=1187
Score = 39.3 bits (90), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 38/138 (28%), Positives = 59/138 (43%), Gaps = 11/138 (8%)
Query 481 YLRGNLAESKCYLITVTPVYADGPG------SPESIKAYLKQAPPSKGPTVRTKKVGKNE 534
YL L YL+ +T G G S + KA +AP K P +R + +
Sbjct 568 YLLEGLRPDSVYLVRITAATRIGWGEASLWTSHRTPKATSVKAP--KSPELRLEPINCTT 625
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA-VNVDSSHTEYTLSSLTSDTLYMVRMA 593
++W Q D I+ Y ++Y+ E + +D+S EYT+S L Y VR+
Sbjct 626 ITVQWQQDSDD--TAAIQGYKLYYKEEGQQENGPILLDASDLEYTVSGLDPRRKYHVRLL 683
Query 594 AYTDEGGKDGPEFTFTTP 611
AY + + T +TP
Sbjct 684 AYNNMEEGYQADQTVSTP 701
Score = 38.5 bits (88), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 39/175 (22%), Positives = 75/175 (43%), Gaps = 19/175 (11%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYN 258
AEN+ G V S + + +P+ P+N +++E +SS + L W P S ++ Y+
Sbjct 389 AENSQGSVLSRARLTVVMSEDRPSAPYN---VHAETMSSSAILLAWERPLYNSDKVIAYS 445
Query 259 IQYRTKDA---STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+ Y + + + DT + + + DL+P + Y F I G S S+
Sbjct 446 VHYMKAEGLNNEEYQVVIGNDT----THYIIDDLEPASNYTFYIVAYMPLGA---SQMSD 498
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
+ T ED P +AP ++ + + W +P G+++ Y ++
Sbjct 499 HVTQHTLEDVPLRAPEISLT-----SRSPTDILISWLPIPAKYRRGQVVLYRLSF 548
Score = 34.3 bits (77), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 23/96 (24%), Positives = 43/96 (45%), Gaps = 2/96 (2%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV-NVDSSHTEY 577
P + P + + ++ W +P + G + Y + +R ++ V + + EY
Sbjct 509 PLRAPEISLTSRSPTDILISWLPIPAKYRRGQVVLYRLSFRLSTDSKIQVLELPGTSDEY 568
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPEFT-FTTPK 612
L L D++Y+VR+ A T G + +T TPK
Sbjct 569 LLEGLRPDSVYLVRITAATRIGWGEASLWTSHRTPK 604
>sp|Q53EP0|FND3B_HUMAN Fibronectin type III domain-containing
protein 3B OS=Homo sapiens OX=9606 GN=FNDC3B PE=1 SV=2
Length=1204
Score = 39.3 bits (90), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 84/343 (24%), Positives = 117/343 (34%), Gaps = 59/343 (17%)
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
++DL+P T+Y R+ M KG SE S T+ S AP + +H +
Sbjct 342 LKDLRPATDYHVRVYAMYNSVKG---SCSEPVSFTTH----SCAPECPFPPKLAH-RSKS 393
Query 346 TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT--------KLTVNLTNDRYL 397
++ L WK P + KI +Y L W +N KLT Y
Sbjct 394 SLTLQWKA--PIDNGSKITNY---LLEWDEGKRNSGFRQCFFGSQKHCKLTKLCPAMGYT 448
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVM-DLKAFPKDNMLWV--EWTTPR----ESV 450
L RN +G S + + C P M + + WV +W+ P E V
Sbjct 449 FRLAARNDIGTSGYSQEVV--CYTLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCSPEEV 506
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR-------GNLAESKCYLITVTPVYADG 503
Y LE + D H Y NL S Y +T +G
Sbjct 507 ITYTLE-----------IQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEG 555
Query 504 PGSPESIKAYLKQAPPSKGPTVR---TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
P + +P GP R V + ++WD P D I Y +
Sbjct 556 KSCPSEVLV-CTTSPDRPGPPTRPLVKGPVTSHGFSVKWDP-PKDNGGSEILKYLL--EI 611
Query 561 IIGNETA----VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
GN A V S TEYT + L TLY +R + G
Sbjct 612 TDGNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRACCISTGG 654
>sp|Q62234|MYOM1_MOUSE Myomesin-1 OS=Mus musculus OX=10090 GN=Myom1
PE=1 SV=2
Length=1667
Score = 39.3 bits (90), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 29/101 (29%), Positives = 45/101 (45%), Gaps = 3/101 (3%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
+P V P PP +LSV +E S + L+W P + + Y ++ A W ++
Sbjct 611 EPTEGVIPGPPTDLSV--TEATRSYVVLSWKPPGQRGHEGIMYFVEKCDVGAENWQRVNT 668
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
E + F + DL Y FR+RC G G S+ +E
Sbjct 669 ELPVKS-PRFALFDLVEGKSYRFRVRCSNSAGVGEPSETTE 708
Score = 36.6 bits (83), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 32/108 (30%), Positives = 45/108 (42%), Gaps = 10/108 (9%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDAS--TWSQIPPEDTA 278
P PPH++ + SE + L L W P + Y + + A W + + A
Sbjct 1021 PGPPHSVKL--SEVRKNSLVLQWKPPVYSGRTPVTGYFVDLKEASAKDDQWRGL--NEAA 1076
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
VQ LK T YVFR+R + + G G SD A + E RP
Sbjct 1077 IVNKYLRVQGLKEGTSYVFRVRAVNQAGVGKPSDL---AGPVVAETRP 1121
Score = 35.0 bits (79), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 28/107 (26%), Positives = 46/107 (43%), Gaps = 3/107 (3%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNIQYRTKDASTWSQIP 273
D +++ P L V++ + + ++W P++ IL Y I TWSQ
Sbjct 481 DADAEIEGAPAAPLDVVSLDANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDTWSQC- 539
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
DT + F V L Y+FR+R + + G G S SE + +
Sbjct 540 -NDTPVKFARFPVTGLIEGRSYIFRVRAVNKTGIGLPSRVSEPVAAL 585
>sp|Q91735|EPHB3_XENLA Ephrin type-B receptor 3 OS=Xenopus laevis
OX=8355 GN=ephb3 PE=2 SV=1
Length=974
Score = 38.9 bits (89), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 35/135 (26%), Positives = 51/135 (38%), Gaps = 7/135 (5%)
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-----SIKAYLKQAPPSKGPT 524
W ++ G R +L Y + V SP ++ QA PS P
Sbjct 374 WPRQLGVTQRLVSVSHLQAHTKYSFEIQAVNGVSGKSPHIPNYFTVNITTNQAAPSSVPM 433
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTS 584
V++ N L W P + NG I +Y I Y V S T + +T
Sbjct 434 VQSHGSLANSLTLSW--APPESPNGIILDYEIKYYAKGHIGAGNTVTSQRTTVRMEGMTP 491
Query 585 DTLYMVRMAAYTDEG 599
DT+Y+V++ A T G
Sbjct 492 DTVYVVQVRARTVAG 506
Score = 36.6 bits (83), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 26/90 (29%), Positives = 45/90 (50%), Gaps = 7/90 (8%)
Query 225 PHNLSVINSE-ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA-STRS 282
P ++ ++ S L++ L L+W P + IIL Y I+Y K I +T S R+
Sbjct 428 PSSVPMVQSHGSLANSLTLSWAPPESPNGIILDYEIKYYAK-----GHIGAGNTVTSQRT 482
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ ++ + P T YV ++R G G +S+
Sbjct 483 TVRMEGMTPDTVYVVQVRARTVAGYGAYSE 512
>sp|P19756|GHR_PIG Growth hormone receptor OS=Sus scrofa OX=9823
GN=GHR PE=1 SV=1
Length=638
Score = 38.9 bits (89), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 50/223 (22%), Positives = 89/223 (40%), Gaps = 36/223 (16%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLK--------SEWATHKFADCKAKRDTP 179
KPK C E + C W G L++ +++ EW T ++ +C P
Sbjct 50 KPKFTKCRSPELETFSCHWTDGVRHGLQSPGSIQLFYIRRSTQEW-TQEWKEC------P 102
Query 180 TSCTVDYSTVYFVN--IEVWVEAENAL--GKVTSDHINFDPVYKVKPNPPHNLS----VI 231
+ ++ YF + +W+ L T D F V+P+PP L+ I
Sbjct 103 DYVSAGENSCYFNSSYTSIWIPYCIKLTSNGGTVDQKCFSVEEIVQPDPPIGLNWTLLNI 162
Query 232 NSEELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
+ + + +++ W P V I+L+Y +QY+ + + W + P +S V
Sbjct 163 SLTGIHADIQVRWEPPPNADVQKGWIVLEYELQYKEVNETQWKMMDP----VLSTSVPVY 218
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
L+ EY R+R + + + Y E S + Y P +P
Sbjct 219 SLRLDKEYEVRVRSRQRNSEKY-----GEFSEVLYVTLPQMSP 256
>sp|B1AUH1|PTPRU_MOUSE Receptor-type tyrosine-protein phosphatase
U OS=Mus musculus OX=10090 GN=Ptpru PE=1 SV=1
Length=1446
Score = 38.9 bits (89), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 33/124 (27%), Positives = 56/124 (45%), Gaps = 9/124 (7%)
Query 504 PGSPESIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII 562
PG P + + K A P++ P + ++ + L+W+ L +V ++ YR +
Sbjct 370 PGPP--LISRTKCAEPTRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYAVSLCYRYTL 427
Query 563 G---NET---AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
G N+T V ++ + YT+ +L VR+ EG K+G E TF T + G
Sbjct 428 GGSHNQTIRECVKMERGASRYTIKNLLPFRNIHVRLILTNPEGRKEGKEVTFQTDEDVPG 487
Query 617 EIEA 620
I A
Sbjct 488 GIAA 491
>sp|O88307|SORL_MOUSE Sortilin-related receptor OS=Mus musculus
OX=10090 GN=Sorl1 PE=1 SV=3
Length=2215
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 89/399 (22%), Positives = 160/399 (40%), Gaps = 45/399 (11%)
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD 265
K SD + VYKV+ NL + + S + LTW P YN+ YR
Sbjct 1547 KACSDELT---VYKVQ-----NLQW--TADFSGDVTLTWMRPKKMPSASCVYNVYYRVVG 1596
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR--CMKEDGKGYWSDWSEEASGITYE 323
S W + +T S ++S ++ LKP T Y +++ C+ + + ++ + T E
Sbjct 1597 ESIWKTL---ETHSNKTSTVLKVLKPDTTYQVKVQVHCLNK-----VHNTNDFVTLRTPE 1648
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL---QNY 380
P + ++ S +G ++ PP +G I +Y V +R S + Q
Sbjct 1649 GLPDAPRNLQLSLN-SEEEGV----ILGHWAPPVHTHGLIREYIVEYSRSGSKMWASQRA 1703
Query 381 TVNATKLTVNLTNDRY---LATLTVRNLVGKSDA-AVLTIPACDFQATHPVMDLKAFPKD 436
N+T++ L N Y +A +T R + SD+ ++ TI QA P + + ++ ++
Sbjct 1704 ASNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSITTIKGKVIQA--PNIHIDSYDEN 1761
Query 437 NMLWVEWTTPRESVKKYI--LEWCVLSDKAPCIT-DWQQEDGTVHRTYLRGNLAESKCYL 493
++ + V Y+ L W + K T ++ HR NL Y
Sbjct 1762 SLSFTLTMDGDIKVNGYVVNLFWSFDAHKQEKKTLSFRGGSALSHRV---SNLTAHTSYE 1818
Query 494 ITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
I+ D SP + + L + P+++ K + + W P +V G
Sbjct 1819 ISAW-AKTDLGDSPLAFEHILTRGSSPPAPSLKAKAINQTAVECIWTG-PKNVVYGIF-- 1874
Query 554 YTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
Y + + N +V S H + + S L++VR+
Sbjct 1875 YATSFLDLYRNPKSVTT-SLHNKTVIVSKDEQYLFLVRV 1912
Score = 35.8 bits (81), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 89/390 (23%), Positives = 140/390 (36%), Gaps = 56/390 (14%)
Query 222 PNPPHNLSV-INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P+ P NL + +NSEE IL W P +I +Y ++Y + W+ +
Sbjct 1651 PDAPRNLQLSLNSEEEGVILG-HWAPPVHTHGLIREYIVEYSRSGSKMWAS-----QRAA 1704
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE---------EASGITYEDRPSKAPS 331
+S +++L Y R+ + G G WSD +A I + + S
Sbjct 1705 SNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSITTIKGKVIQAPNIHIDSYDENSLS 1764
Query 332 FWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL 391
F +D V L W + + K L + R S L + N T T
Sbjct 1765 FTLTMDGDIKVNGYVVNLFW-SFDAHKQEKKTLSF-----RGGSALSHRVSNLTAHT--- 1815
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE--WTTPRES 449
Y + + +G S A I P + KA N VE WT P+
Sbjct 1816 ---SYEISAWAKTDLGDSPLAFEHILTRGSSPPAPSLKAKAI---NQTAVECIWTGPKNV 1869
Query 450 VKK--YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
V Y + L +T ++H + + E +L+ V Y P
Sbjct 1870 VYGIFYATSFLDLYRNPKSVTT------SLHNKTVIVSKDEQYLFLVRVLIPYQ----GP 1919
Query 508 ESIKAYLKQAPPSKGP--TVRTKKVGKNEAVLEWDQLPVDV--QNGFIRNYTIFYRTII- 562
S +K P S+ P + +GK A+++W+ P D Q+ F Y I + +I
Sbjct 1920 SSDYVVVKMIPDSRLPPRHLHAVHIGKTSALIKWES-PYDSPDQDLF---YAIAVKDLIR 1975
Query 563 --GNETAVNVDSSHTEYTLSSLTSDTLYMV 590
V +S EY+LS L Y +
Sbjct 1976 KTDRSYKVRSRNSTVEYSLSKLEPGGKYHI 2005
>sp|Q63132|ROS1_RAT Proto-oncogene tyrosine-protein kinase ROS
OS=Rattus norvegicus OX=10116 GN=Ros1 PE=2 SV=1
Length=2338
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 51/193 (26%), Positives = 82/193 (42%), Gaps = 24/193 (12%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPE----DTASTRSSFTVQDLKPF 292
S+ + L W +I V KY IQ++ ++Q+P +T S + S+ V+ L PF
Sbjct 121 SNGVTLRWNPANISGV---KYIIQWK------YAQLPGSWAYTETVS-KLSYMVEPLHPF 170
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
TEY+FR+ + +S S +Y P P I + TV++ W
Sbjct 171 TEYIFRVVWIFTAQLHLYSPPSP-----SYRTHPYGVPETAPFITNIESSSPDTVEVSWA 225
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT-KLTVNLTNDRYLATLTVRNLVGKSDA 411
PP+ G IL Y + L L + T + + L N Y ++ N VG+
Sbjct 226 --PPYFPGGPILGYNLRLISKTQKLDSGTQRTSFQFYSTLPNTTYRFSIAAVNEVGEGPE 283
Query 412 A--VLTIPACDFQ 422
A ++T P+ Q
Sbjct 284 AESMITTPSPAVQ 296
>sp|P22105|TENX_HUMAN Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB
PE=1 SV=5
Length=4244
Score = 38.9 bits (89), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 24/76 (32%), Positives = 40/76 (53%), Gaps = 7/76 (9%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PPH + +EE SS L+L+WT + + +QYR D + +P A+ + +
Sbjct 3449 PPHLGELTVAEETSSSLRLSWT---VAQGPFDSFVVQYRDTDGQPRA-VP---VAADQRT 3501
Query 284 FTVQDLKPFTEYVFRI 299
TV+DL+P +Y F +
Sbjct 3502 VTVEDLEPGKKYKFLL 3517
>sp|P31785|IL2RG_HUMAN Cytokine receptor common subunit gamma
OS=Homo sapiens OX=9606 GN=IL2RG PE=1 SV=1
Length=369
Score = 38.5 bits (88), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 32/118 (27%), Positives = 51/118 (43%), Gaps = 8/118 (7%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
V P P NL++ E S L+L W N + L++ +QYRT +W+ E +
Sbjct 152 VIPWAPENLTLHKLSE--SQLELNWNNRFLNHC--LEHLVQYRTDWDHSWT----EQSVD 203
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
R F++ + Y FR+R G WSE + I + SK F + ++
Sbjct 204 YRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALE 261
>sp|Q07496|EPHA4_CHICK Ephrin type-A receptor 4 OS=Gallus gallus
OX=9031 GN=EPHA4 PE=1 SV=2
Length=986
Score = 38.9 bits (89), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 26/88 (30%), Positives = 46/88 (52%), Gaps = 4/88 (5%)
Query 225 PHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P +++I ++E++ + L W P + +IL+Y ++Y KD + S + TAS +
Sbjct 441 PSPIALIQAKEITRHSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVK-TASRNTD 499
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
++ L P T YVF +R G G +S
Sbjct 500 --IKGLNPLTSYVFHVRARTAAGYGDFS 525
>sp|Q60805|MERTK_MOUSE Tyrosine-protein kinase Mer OS=Mus musculus
OX=10090 GN=Mertk PE=1 SV=1
Length=994
Score = 38.9 bits (89), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 45/180 (25%), Positives = 75/180 (42%), Gaps = 17/180 (9%)
Query 199 EAENALGKVTSD--HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK 256
EA N G S HIN KV P+PP + ++NS S + ++W P L+
Sbjct 258 EAHNDKGLTVSKGVHINI----KVIPSPPTEVHILNSTAHS--ILVSWV-PGFDGYSPLQ 310
Query 257 -YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+IQ + D + + +T+++ + +Q L+ Y + C E G WS S
Sbjct 311 NCSIQVKEADRLSNGSVMVFNTSASPHLYEIQQLQALANYSIAVSCRNEIG---WSAVSP 367
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
T E PS AP I + + + W P +G+++ Y ++ W+S
Sbjct 368 WILASTTEGAPSVAP---LNITVFLNESNNILDIRWTKPPIKRQDGELVGYRISHV-WES 423
>sp|P32018|COEA1_CHICK Collagen alpha-1(XIV) chain OS=Gallus gallus
OX=9031 GN=COL14A1 PE=1 SV=2
Length=1888
Score = 38.9 bits (89), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 40/123 (33%), Positives = 56/123 (46%), Gaps = 11/123 (9%)
Query 492 YLITVTPVYADGPGSP-ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
Y +TV ++ + P + L +PPS ++ VG N A L WD +V
Sbjct 510 YTVTVYAMFGEEASDPLTGQETTLPLSPPSN---LKFSDVGHNSAKLTWDPASKNV---- 562
Query 551 IRNYTIFYRTIIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT 609
+ Y I Y G ET V V T +TL SLT+ T Y V + + DEG + +FT
Sbjct 563 -KGYRIMYVKTDGTETNEVEVGPVST-HTLKSLTALTEYTVAIFSLYDEGQSEPLTGSFT 620
Query 610 TPK 612
T K
Sbjct 621 TRK 623
>sp|Q1KL86|EPHA2_MACFA Ephrin type-A receptor 2 OS=Macaca fascicularis
OX=9541 GN=EPHA2 PE=2 SV=1
Length=976
Score = 38.5 bits (88), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 52/205 (25%), Positives = 84/205 (41%), Gaps = 23/205 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW-----DGGRETHLETNFTLKSEW-ATHKFADCKAK--- 175
PP P L+ V G K+ W GGRE + + T + W + + C++
Sbjct 328 PPSAPHYLTA-VGMGAKVELRWTPPQDSGGRE-DIVYSVTCEQCWPESGECGPCESSVRY 385
Query 176 RDTPTSCTVDYSTVY----FVNIEVWVEAENAL-GKVTSDHINFDPVYKVKPNPPHNLSV 230
+ P T TV +N VEA N + G VTS V + PP V
Sbjct 386 SEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSFRTASVSINQTEPP---KV 442
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
++ L ++W+ P + + KY + YR K S + + S T+ DL
Sbjct 443 RLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNSYNV----RRTEGFSVTLDDLA 498
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSE 315
P T Y+ +++ + ++G+G S E
Sbjct 499 PDTTYLVQVQALTQEGQGAGSKVHE 523
>sp|Q6WG24|IL4RA_HORSE Interleukin-4 receptor subunit alpha OS=Equus
caballus OX=9796 GN=IL4R PE=2 SV=2
Length=809
Score = 38.5 bits (88), Expect = 0.32, Method: Compositional matrix adjust.
Identities = 45/187 (24%), Positives = 71/187 (38%), Gaps = 35/187 (19%)
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVW---------VEAENALGKVTSDHI---------- 212
C+ K D PT+C+ Y +N E E E + ++ D+I
Sbjct 44 CEWKMDRPTNCSAQLRLSYQLNDEFSDNLTCIPENREDEVCVCRMLMDNIVSEDVYELDL 103
Query 213 ----------NFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVII--LKYNI 259
+F P VKP P NL+V +S LTW+NP +K+ + L Y +
Sbjct 104 WAGNQLLWNSSFKPSRHVKPRAPQNLTV---HAISHTWLLTWSNPYPLKNHLWSELTYLV 160
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+D T +I T LK Y R++ ++ WS+WS +
Sbjct 161 NISKEDDPTDFKIYNVTYMDPTLRVTASTLKSRATYSARVKARAQNYNSTWSEWSPSTTW 220
Query 320 ITYEDRP 326
Y ++P
Sbjct 221 HNYYEQP 227
>sp|Q28902|COCA1_RABIT Collagen alpha-1(XII) chain (Fragment)
OS=Oryctolagus cuniculus OX=9986 GN=COL12A1 PE=2 SV=1
Length=639
Score = 38.5 bits (88), Expect = 0.32, Method: Compositional matrix adjust.
Identities = 21/51 (41%), Positives = 28/51 (55%), Gaps = 0/51 (0%)
Query 549 GFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
G +R Y + Y+T + V VD S T +L L S TLY V ++A DEG
Sbjct 334 GKVRKYVVRYQTPEEDVKEVEVDRSRTSTSLKDLLSQTLYTVSVSAVYDEG 384
Score = 37.4 bits (85), Expect = 0.81, Method: Compositional matrix adjust.
Identities = 97/397 (24%), Positives = 154/397 (39%), Gaps = 68/397 (17%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P NL + SE +++WT PS + +Y ++Y + + +S
Sbjct 131 PSNLVI--SERTHRSFRVSWTPPSDS---VDRYKVEYYPVSGGKRQEF---YVSRLETST 182
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF-WYKIDPSHTQG 343
++DLKP TEYV + + ED ++SE G T + P S Y I P+
Sbjct 183 VLKDLKPETEYVVNVYSVVED------EYSEPLKG-TEKTLPVPIVSLNIYDIGPT---- 231
Query 344 YRTVQLVWKTLPPFEANGKILDYE----VTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT 399
T+++ W+ P A G + YE T+ K TVN +LT L + Y T
Sbjct 232 --TMRVQWQ--PVGGATGYTVSYEPVKTTESTKPKEMRVGPTVNDVQLTDLLPSTEYEVT 287
Query 400 L--TVRNLVGK-SDAAVLTIPACDFQ------ATHPVMDL---KAFPKDNMLWVEWTTPR 447
+ + +L + + A +T+P Q TH M + K V + TP
Sbjct 288 VQAVLHDLTSEPATAREMTLPLPRPQDVKLRDVTHSTMSVFWEPVLGKVRKYVVRYQTPE 347
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
E VK+ V D++ T + +L Y ++V+ VY +G P
Sbjct 348 EDVKE------VEVDRSRTSTSLK-------------DLLSQTLYTVSVSAVYDEGESPP 388
Query 508 ESIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET 566
+ + + P PT +R +V WD DV R + + ET
Sbjct 389 VTAQETTRPVP---APTNLRITEVTPESFRGTWDHGASDVS--LYRITWAPFGSSDKMET 443
Query 567 AVNVDSSHTEYTLSSLTSDTLYMVRMAA-YTDEGGKD 602
+N D + +L +TLY V + A Y DE D
Sbjct 444 ILNGDENT--LVFENLNPNTLYEVSVTAIYPDESESD 478
>sp|Q9R044|NPHN_RAT Nephrin OS=Rattus norvegicus OX=10116 GN=Nphs1
PE=1 SV=2
Length=1252
Score = 38.5 bits (88), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 33/109 (30%), Positives = 50/109 (46%), Gaps = 10/109 (9%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A NALG SDH N V +P+PP L V++ S + L W P + ++ I
Sbjct 936 ATNALG---SDHTNIQLVSISRPDPPLGLKVVSISPHS--VGLEW-KPGFDGGLPQRFQI 989
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
+Y + + + T +T +FT+ LKP T Y RI + + G
Sbjct 990 RYEALETPGFLHVDVLPTQAT--TFTLTGLKPSTRY--RIWLLASNALG 1034
>sp|P28192|PTP4_CAEEL Tyrosine-protein phosphatase 4 OS=Caenorhabditis
elegans OX=6239 GN=ptp-4 PE=2 SV=3
Length=1159
Score = 38.5 bits (88), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 38/149 (26%), Positives = 61/149 (41%), Gaps = 21/149 (14%)
Query 173 KAKRDTPTS-----CTVDYSTVYFVNIEVWVEAENALGKVTSDHINF---DPVYKVKPNP 224
K D PTS C + ST Y + IE A+N G + F D V P+
Sbjct 285 KMTFDKPTSTPLTICALSPSTDYALAIE----ADNGFGTSPQATLVFHTEDSVPNWSPST 340
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWS----QIPPEDTAS 279
L V+ E++ + W P + + ++KY++ Y+ K+ W + P S
Sbjct 341 ITTLPVVGKPEITVL----WPAPPLNATEKVIKYHLYYKAKNEDQWKIEHLNVSPNGVKS 396
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
+ + DL P T+Y R+ G+G
Sbjct 397 KLFKYRLVDLNPNTQYRIRVSASTIKGEG 425
Score = 35.0 bits (79), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 35/135 (26%), Positives = 61/135 (45%), Gaps = 19/135 (14%)
Query 240 LKLTWTNPSIKS-VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ L WT+ + ++ IL++++ RT +T + A+T V +L P+T Y F
Sbjct 156 ITLVWTHNAARAHRPILRFSVSVRTVSDNTRFVMAAPSNATT---VIVDNLSPYTLYAFS 212
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV--QLVWKTL-P 355
+R G SD+ E + T + P++ P Q R + + V T+ P
Sbjct 213 VRAENSAGS---SDFGPETTFRTLGESPNRPPQI---------QKIRNITSECVEVTITP 260
Query 356 PFEANGKILDYEVTL 370
P E NG++ Y V +
Sbjct 261 PDEMNGELDKYLVLI 275
>sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo
sapiens OX=9606 GN=AXL PE=1 SV=4
Length=894
Score = 38.5 bits (88), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 33/125 (26%), Positives = 52/125 (42%), Gaps = 17/125 (14%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY- 257
EA NA G TS V P P NL +++ + + L++ WT P + + L +
Sbjct 206 EAHNAKGVTTSRTATI----TVLPQQPRNLHLVSRQ--PTELEVAWT-PGLSGIYPLTHC 258
Query 258 NIQYRTKDASTWSQI----PPEDTASTRSS-----FTVQDLKPFTEYVFRIRCMKEDGKG 308
+Q D Q PPE+ ++++S + L P T Y R+ C G
Sbjct 259 TLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPS 318
Query 309 YWSDW 313
W+ W
Sbjct 319 SWTHW 323
>sp|P57097|MERTK_RAT Tyrosine-protein kinase Mer OS=Rattus norvegicus
OX=10116 GN=Mertk PE=2 SV=1
Length=994
Score = 38.5 bits (88), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 42/178 (24%), Positives = 75/178 (42%), Gaps = 13/178 (7%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK-Y 257
EA N G S + + KV P+PP + ++NS S + ++W P L+
Sbjct 258 EAHNDKGLTVSKGVQIN--IKVIPSPPTEVHILNSTAHS--ILVSWV-PGFDGYSPLQNC 312
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
+IQ + D + + +T+++ + VQ L+ Y + C E G WS S
Sbjct 313 SIQVKEADQLSNGSVMVFNTSASPHLYEVQQLQALANYSVTVSCRNEIG---WSAVSPWI 369
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
T E P+ AP I + +++ W P +G+++ Y ++ W+S
Sbjct 370 LASTTEGAPAVAP---LNITVFLNESSNNLEIRWTKPPIKRQDGELVGYRISHV-WES 423
>sp|Q02173|MPSF_CHICK M-protein, striated muscle OS=Gallus gallus
OX=9031 PE=2 SV=1
Length=1450
Score = 38.5 bits (88), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 40/148 (27%), Positives = 63/148 (43%), Gaps = 10/148 (7%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNIQYRTKDASTWSQIPPEDTAST 280
P+ PH ++++N + S + L W P IL Y I R + W ++ + +
Sbjct 699 PSYPHGITLLNCDGHS--MTLGWKAPKYSGGSPILGYYIDKREANHKNWHEV--NSSVIS 754
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
R+ +TV+DL Y F+I G G+ SD SE + P P+ Y +
Sbjct 755 RTIYTVEDLTEDAFYEFKIAAANVVGIGHPSDPSEHFKCKAW-TMPEPGPA--YDLTVCE 811
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEV 368
+ V L+WK P +E I Y V
Sbjct 812 VRNTSLV-LLWKA-PVYEGKSPITGYLV 837
Score = 37.7 bits (86), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 72/318 (23%), Positives = 127/318 (40%), Gaps = 29/318 (9%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
V P+ P + + + S +++ W P + + Y I Y ++ W P
Sbjct 598 VVPSAPGRVVATRNTKTSVVVQ--WDKPKHEENL-YGYYIDYSVVGSNQWE--PANHKPI 652
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
+ F V L+ +Y+FR++ + G +S+ S+E+ I + + PS+ + I
Sbjct 653 NYNRFVVHGLETGEQYIFRVKAVNAVG---FSENSQESEAIKVQAALT-CPSYPHGITLL 708
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV------NLTN 393
+ G+ ++ L WK P + IL Y + R +H + VN++ ++ +LT
Sbjct 709 NCDGH-SMTLGWKA-PKYSGGSPILGYYID-KREANHKNWHEVNSSVISRTIYTVEDLTE 765
Query 394 DR-YLATLTVRNLVG---KSDAAV-LTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPR 447
D Y + N+VG SD + A P DL ++ L + W P
Sbjct 766 DAFYEFKIAAANVVGIGHPSDPSEHFKCKAWTMPEPGPAYDLTVCEVRNTSLVLLWKAPV 825
Query 448 ESVKKYILEWCVLSDKAPCITDW--QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
K I + V K DW E T HR + +L + Y+ V V G G
Sbjct 826 YEGKSPITGYLV-DYKEVDTEDWITANEKPTSHRYFKVTDLHQGHTYVFKVRAVNDAGVG 884
Query 506 SPESIK--AYLKQAPPSK 521
I +++ +P +K
Sbjct 885 KSSEISEPVFVEASPGTK 902
>sp|Q28824|MYLK_BOVIN Myosin light chain kinase, smooth muscle
OS=Bos taurus OX=9913 GN=MYLK PE=1 SV=1
Length=1176
Score = 38.5 bits (88), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 39/117 (33%), Positives = 53/117 (45%), Gaps = 11/117 (9%)
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNI 259
EN LG + +N V K P+PP S+ SS L L+W S + Y++
Sbjct 573 ENKLGSRQA-QVNLTVVDK--PDPPAGTPCA-SDIRSSSLTLSWYGSSYDGGSAVQSYSV 628
Query 260 QYRTKDASTWSQIPPEDTASTRS-SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+ TW ++ A+ RS SF VQDL P EY FR+R + G S SE
Sbjct 629 EIWDSVDKTWKEL-----ATCRSTSFNVQDLLPDREYKFRVRAINVYGTSEPSQESE 680
>sp|Q3KNY0|IGFN1_MOUSE Immunoglobulin-like and fibronectin type
III domain-containing protein 1 OS=Mus musculus OX=10090 GN=Igfn1
PE=1 SV=3
Length=2849
Score = 38.5 bits (88), Expect = 0.41, Method: Composition-based stats.
Identities = 77/329 (23%), Positives = 119/329 (36%), Gaps = 51/329 (16%)
Query 221 KPNPPHN-LSVINSEELSSILKLTWTNPSIKS-VIILKYNIQYRTKDASTWSQI--PPED 276
KP PP L V + L+ W P +I Y ++ R STW ++ PP D
Sbjct 2241 KPQPPQGPLEVQDCHRAGVCLR--WLPPRDNGGQVIQHYVVERRQAGRSTWLKVGEPPSD 2298
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ +SFT ++ +Y FR+R + G G + E P AP+
Sbjct 2299 S----TSFTDTSVEQGKKYAFRVRAVTSVGAGDALESEEVLVAPEALPGPPSAPAIL--- 2351
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH----LQNYTVNATKLTVNLT 392
+ +++ L W P + IL Y + + S+ + V+ + TV
Sbjct 2352 ----SASSQSITLTWGA-PQGPGSNHILGYLIEKHKKGSNTWMAVNEQPVSERRYTVVGL 2406
Query 393 ND--RYLATLTVRNLVGKSDAAVLTIPACD-------FQATHPVMDLKAFPKDNM-LWVE 442
+Y +T L G D P D + PV DL+ N + V
Sbjct 2407 RQGCQYEFRVTAVTLSGPGDPG----PPSDAVFARDPMRPPGPVRDLQVTDTSNTSITVS 2462
Query 443 WTTP----RESVKKYILEWCVLSDK---APCITDWQQEDGTV-HRTYLRGNLAESKCYLI 494
W P + + YI+E C SD +PC GTV T+ L + Y +
Sbjct 2463 WMVPDARDADEAQGYIVELCG-SDSHQWSPC------HVGTVPGTTFTAKGLRPQEGYFV 2515
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGP 523
VT V G S+ + P + P
Sbjct 2516 RVTAVNDGGRSQATSLDTLVHAMPATVCP 2544
>sp|Q973G3|Y939_SULTO Kelch domain-containing protein STK_09390
OS=Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 /
NBRC 100140 / 7) OX=273063 GN=STK_09390 PE=3 SV=1
Length=709
Score = 38.1 bits (87), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 45/170 (26%), Positives = 67/170 (39%), Gaps = 22/170 (13%)
Query 441 VEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY 500
V+W S YI W S K G V +Y +L + Y I + P
Sbjct 333 VKWYDTNAS-GYYITYWSNFSQKVTI------NVGNV-TSYTIKHLKDGVTYYIQIVPYN 384
Query 501 ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF--IRNYTIFY 558
+ G G+P I + + P+ P + K+G A L W D NG I Y ++
Sbjct 385 SLGNGTPSDIISATPSSVPN--PPIIKVKIGNLNATLTW----YDTFNGGYPIEGYYLYV 438
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
N +NV + T Y L++LT+ LY + + AY G +F
Sbjct 439 -----NGKGINVGN-ITSYVLTNLTAGELYTIELIAYNKIGNSSISSVSF 482
>sp|P19941|GHR_RABIT Growth hormone receptor OS=Oryctolagus cuniculus
OX=9986 GN=GHR PE=1 SV=1
Length=638
Score = 37.7 bits (86), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 52/225 (23%), Positives = 90/225 (40%), Gaps = 40/225 (18%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLK--------SEWATHKFADCKAKRDTP 179
KPK C E + C W G L++ +++ EW T ++ +C P
Sbjct 50 KPKFTKCRSPELETFSCHWTDGVHHGLKSPGSVQLFYIRRNTQEW-TQEWKEC------P 102
Query 180 TSCTVDYSTVYF------VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS-VIN 232
+ ++ YF + I ++ N G V D F V+P+PP L+ +
Sbjct 103 DYVSAGENSCYFNSSYTSIWIPYCIKLTNNGGMV--DQKCFSVEEIVQPDPPIGLNWTLL 160
Query 233 SEELSSI---LKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
+ L+ I +++ W P V I+L+Y +QY+ + + W + P +S
Sbjct 161 NVSLTGIHADIQVRWEPPPNADVQKGWIVLEYELQYKEVNETQWKMMDP----VLSTSVP 216
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
V L+ EY R+R + + Y E S + Y P +P
Sbjct 217 VYSLRLDKEYEVRVRSRQRSSEKYG-----EFSEVLYVTLPQMSP 256
>sp|P16170|NCA11_XENLA Neural cell adhesion molecule 1-A OS=Xenopus
laevis OX=8355 GN=ncam1-a PE=2 SV=1
Length=1088
Score = 38.1 bits (87), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 35/130 (27%), Positives = 55/130 (42%), Gaps = 7/130 (5%)
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHIN-----FDPVYKVKPNPPHNLSVINSEELSSIL 240
YS ++EV ++EN G IN F V+ + P + ++ E SS +
Sbjct 450 YSGPTSSSLEVNPDSENDFGNYNCTAINTIGHEFSEFILVQADTPSSPAIRKVEPYSSTV 509
Query 241 KLTWTNP-SIKSVIILKYNIQYRTKDASTW-SQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ + P S V ILKY ++R W ++ + S TV LKP T Y+ +
Sbjct 510 MIVFDEPDSTGGVPILKYKAEWRVIGHEKWHTKYYDAKEVNAESIITVMGLKPETSYMVK 569
Query 299 IRCMKEDGKG 308
+ M G G
Sbjct 570 LSAMNGKGLG 579
>sp|B3EX02|MFP1_ACRMI MAM and fibronectin type III domain-containing
protein 1 (Fragment) OS=Acropora millepora OX=45264 PE=1
SV=1
Length=422
Score = 37.4 bits (85), Expect = 0.56, Method: Compositional matrix adjust.
Identities = 35/119 (29%), Positives = 56/119 (47%), Gaps = 9/119 (8%)
Query 496 VTPVYADGPGS---PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
V+ V DG GS ++A + PS+ P+V V ++W+ LP NG +
Sbjct 265 VSVVAVDGDGSQFKSTVLQARTDEWVPSRAPSVFVTSVTSTSVTVQWNPLPQQYHNGRLL 324
Query 553 NYTIFYRTIIGNETAV---NVDSSHTEY-TLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
Y +F R + + NV +T + TL++L Y V ++A+T +G DGP T
Sbjct 325 GYRVFIRKTANSPFPLDESNVAVYNTSWVTLNNLKPGQPYEVNVSAFTSKG--DGPRST 381
>sp|P33896|INAR1_MOUSE Interferon alpha/beta receptor 1 OS=Mus
musculus OX=10090 GN=Ifnar1 PE=1 SV=2
Length=590
Score = 37.7 bits (86), Expect = 0.59, Method: Compositional matrix adjust.
Identities = 24/90 (27%), Positives = 48/90 (53%), Gaps = 5/90 (6%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP-EDTASTRS 282
PP N+ V ++ + LK + S+ SV ++ +YRTKD + W ++P + T +T+
Sbjct 31 PPENIDVYIIDD-NYTLKWSSHGESMGSVT---FSAEYRTKDEAKWLKVPECQHTTTTKC 86
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
F++ D + + FR+R + + W++
Sbjct 87 EFSLLDTNVYIKTQFRVRAEEGNSTSSWNE 116
>sp|P79108|GHR_BOSIN Growth hormone receptor OS=Bos indicus OX=9915
GN=GHR PE=2 SV=1
Length=634
Score = 37.7 bits (86), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 46/198 (23%), Positives = 81/198 (41%), Gaps = 29/198 (15%)
Query 129 PKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKF---ADCKAKRDTPTSCTVD 185
PK C E + C W G N +L+S + F D + ++ P +
Sbjct 51 PKFTKCRSPELETFSCHWTDG------ANHSLQSPGSVQMFYIRRDIQEWKECPDYVSAG 104
Query 186 YSTVYFVN--IEVW----VEAENALGKVTSDHINFDPVYKVKPNPPHNLS----VINSEE 235
++ YF + VW ++ + G V DH F V+P+PP L+ I+ E
Sbjct 105 ENSCYFNSSYTSVWTPYCIKLTSNGGIV--DHKCFSVEDIVQPDPPVGLNWTLLNISLTE 162
Query 236 LSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ + + + W P V IIL+Y + Y+ + + W + P +S + L+
Sbjct 163 IHADILVKWEPPPNTDVKMGWIILEYELHYKELNETQWKMMDP----LMVTSVPMYSLRL 218
Query 292 FTEYVFRIRCMKEDGKGY 309
EY R+R + + + Y
Sbjct 219 DKEYEVRVRTRQRNTEKY 236
>sp|P31836|NCAM1_BOVIN Neural cell adhesion molecule 1 OS=Bos
taurus OX=9913 GN=NCAM1 PE=1 SV=1
Length=853
Score = 37.7 bits (86), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 43/172 (25%), Positives = 71/172 (41%), Gaps = 25/172 (15%)
Query 176 RDTPTSCTVDYSTVYFVN------IEVWVEAENALG--------KVTSDHINFDPVYKVK 221
RD + +YS + N +EV ++EN G ++ + + F V+
Sbjct 449 RDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEF---VLVQ 505
Query 222 PNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTW-SQIPPEDTAS 279
+ P + S+ E SS ++ + P + V ILKY ++R W S+ AS
Sbjct 506 ADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAMGEEVWHSKWYDAKEAS 565
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
T+ LKP T Y R+ + G G S SE ++ +P + PS
Sbjct 566 MEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASE------FKTQPVREPS 611
>sp|Q98902|L1CAM_TAKRU Neural cell adhesion molecule L1 OS=Takifugu
rubripes OX=31033 GN=l1cam PE=3 SV=1
Length=1277
Score = 37.7 bits (86), Expect = 0.66, Method: Compositional matrix adjust.
Identities = 48/198 (24%), Positives = 87/198 (44%), Gaps = 18/198 (9%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDG-GRET---HLETNFTLKSEWATHKFADCKAKRD-- 177
+P E P NL ++ +R W +ET HL + + W H+ + + +
Sbjct 825 VPLEAPLNLGVLLENSTTIRVTWSAVDKETVRGHL-LGYKIYLTWGHHRNSRAQEPENIV 883
Query 178 -TPTSCTVDYSTVY----FVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVI 231
T + ++ + + ++ + A N+ G+ S+ +F V P PP ++ +
Sbjct 884 MVQTGANEEKKSITNLRPYCHYDLAISAFNSKGEGPLSEKTSFMTPEGV-PGPPMSMQMT 942
Query 232 NSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR-SSFTVQDLK 290
+ E S + L WT PS + I+L Y++QYR K S + + D AS + T++ L
Sbjct 943 SPSE--SEITLHWTPPSKPNGILLGYSLQYR-KMQSDDNPLQVVDIASPEITHLTLKGLD 999
Query 291 PFTEYVFRIRCMKEDGKG 308
+ Y F + GKG
Sbjct 1000 RHSHYQFLLMARTAAGKG 1017
Score = 35.0 bits (79), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 40/158 (25%), Positives = 67/158 (42%), Gaps = 19/158 (12%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVI--ILKYNI-----QYRTKDASTWSQIPPEDT 277
P NL V+ E S+ +++TW+ ++V +L Y I +R A I T
Sbjct 830 PLNLGVL--LENSTTIRVTWSAVDKETVRGHLLGYKIYLTWGHHRNSRAQEPENIVMVQT 887
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
+ ++ +L+P+ Y I G+G SE+ S +T E P P
Sbjct 888 GANEEKKSITNLRPYCHYDLAISAFNSKGEG---PLSEKTSFMTPEGVPG-PPMSMQMTS 943
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
PS ++ + L W PP + NG +L Y + + +S
Sbjct 944 PSESE----ITLHWT--PPSKPNGILLGYSLQYRKMQS 975
>sp|P16872|IL7RA_MOUSE Interleukin-7 receptor subunit alpha OS=Mus
musculus OX=10090 GN=Il7r PE=1 SV=2
Length=459
Score = 37.4 bits (85), Expect = 0.66, Method: Compositional matrix adjust.
Identities = 43/191 (23%), Positives = 79/191 (41%), Gaps = 19/191 (10%)
Query 554 YTIFYRTIIGNETAVNVDSSHTEYTL--SSLTSDTLYMVRMAAYTDEGGKDG------PE 605
+ + YR G +V HT T+ L +Y +++ + G P
Sbjct 165 HDVAYRPARGESNWTHVSLFHTRTTIPQRKLRPKAMYEIKVRSIPHNDYFKGFWSEWSPS 224
Query 606 FTFTTPKFA-QGEIEAIVVPVCLAFLLTTLLGVLFC---FNKRDLIKKHIWPNVPDPSKS 661
TF TP+ QG + ++ V + L + L V+ + KR IK +WP++PD K+
Sbjct 225 STFETPEPKNQGGWDPVLPSVTILSLFSVFLLVILAHVLWKKR--IKPVVWPSLPDHKKT 282
Query 662 HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINT 721
+ Q N + + + D +V VE + P DL + + E++ T
Sbjct 283 -LEQLCKKPKTSLNVSFNPESFLDCQIHEVKGVEARDEVESFLPNDLPA----QPEELET 337
Query 722 EGHSSGIGGSS 732
+GH + + ++
Sbjct 338 QGHRAAVHSAN 348
Score = 37.0 bits (84), Expect = 0.81, Method: Compositional matrix adjust.
Identities = 34/127 (27%), Positives = 61/127 (48%), Gaps = 12/127 (9%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNP--SIKSVIILKYNIQYR-TKDASTWSQIPPED 276
VK P +L V+ +E + L +T+ P K + +K+++ YR + S W+ +
Sbjct 127 VKAEAPSDLKVVYRKEANDFL-VTFNAPHLKKKYLKKVKHDVAYRPARGESNWTHV---S 182
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDG--KGYWSDWSEEASGITYEDRPSKAPSFWY 334
TR++ + L+P Y ++R + + KG+WS+WS + T+E K W
Sbjct 183 LFHTRTTIPQRKLRPKAMYEIKVRSIPHNDYFKGFWSEWSPSS---TFETPEPKNQGGWD 239
Query 335 KIDPSHT 341
+ PS T
Sbjct 240 PVLPSVT 246
>sp|Q2VWP9|PRTG_RAT Protogenin OS=Rattus norvegicus OX=10116 GN=Prtg
PE=2 SV=1
Length=1193
Score = 37.7 bits (86), Expect = 0.67, Method: Compositional matrix adjust.
Identities = 39/131 (30%), Positives = 56/131 (43%), Gaps = 14/131 (11%)
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPG------SPESIKAYLKQAPPSKGPTVRTK 528
GTVH L G L YL+ +T G G S + KA +AP K P + +
Sbjct 566 GTVHEYLLEG-LEPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAP--KSPELHLE 622
Query 529 KVGKNEAVLEWDQLPVDVQN-GFIRNYTIFYRTIIGNETA-VNVDSSHTEYTLSSLTSDT 586
+ + W Q D ++ IR Y +FY+ E + +D+ YTLS L
Sbjct 623 PLNCTTISVRWLQ---DTEDPAAIRGYKLFYKEEGQQEHGPIFLDTGDLLYTLSGLDPRR 679
Query 587 LYMVRMAAYTD 597
Y VR+ AY +
Sbjct 680 KYHVRLLAYNN 690
Score = 35.8 bits (81), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 38/175 (22%), Positives = 74/175 (42%), Gaps = 19/175 (11%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYN 258
AEN+ G V S + + +P+ P+N +++E +SS + L W P S ++ Y+
Sbjct 392 AENSQGSVLSRARLTVVMSEDRPSAPYN---VHAETMSSSAILLAWERPLYNSDKVIAYS 448
Query 259 IQYRTKDA---STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+ Y + + + DT + + + DL+P + Y F I G S S+
Sbjct 449 VHYMKAEGLNNEEYQVVLGNDT----THYIIDDLEPDSNYTFYIVAYMPMGA---SQMSD 501
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
+ T ED P + P ++ + + W +P G+++ Y ++
Sbjct 502 HVTQNTLEDVPLRPPEISLT-----SRSPTDILISWLPIPAKYRRGQVVLYRLSF 551
Score = 34.3 bits (77), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 20/82 (24%), Positives = 36/82 (44%), Gaps = 1/82 (1%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET-AVNVDSSHTEY 577
P + P + + ++ W +P + G + Y + +R N V + + EY
Sbjct 512 PLRPPEISLTSRSPTDILISWLPIPAKYRRGQVVLYRLSFRLSTENSIQVVELPGTVHEY 571
Query 578 TLSSLTSDTLYMVRMAAYTDEG 599
L L D++Y+VR+ A T G
Sbjct 572 LLEGLEPDSVYLVRITAATRVG 593
>sp|Q12866|MERTK_HUMAN Tyrosine-protein kinase Mer OS=Homo sapiens
OX=9606 GN=MERTK PE=1 SV=2
Length=999
Score = 37.7 bits (86), Expect = 0.67, Method: Compositional matrix adjust.
Identities = 51/231 (22%), Positives = 90/231 (39%), Gaps = 22/231 (10%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
EA N G S + + K P+PP +S+ NS S + ++W +
Sbjct 263 EAHNDKGLTVSKGVQIN--IKAIPSPPTEVSIRNSTAHS--ILISWVPGFDGYSPFRNCS 318
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
IQ + D + + +T++ + ++ L+ Y + CM E G WS S
Sbjct 319 IQVKEADPLSNGSVMIFNTSALPHLYQIKQLQALANYSIGVSCMNEIG---WSAVSPWIL 375
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH-- 376
T E PS AP + + V + W P + +G+++ Y ++ W+S
Sbjct 376 ASTTEGAPSVAP---LNVTVFLNESSDNVDIRWMKPPTKQQDGELVGYRISHV-WQSAGI 431
Query 377 ----LQNYTVNATKLTV-----NLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
L+ N ++ + N T +A +T + SD + IPA
Sbjct 432 SKELLEEVGQNGSRARISVQVHNATCTVRIAAVTRGGVGPFSDPVKIFIPA 482
>sp|O55005|ROBO1_RAT Roundabout homolog 1 OS=Rattus norvegicus
OX=10116 GN=Robo1 PE=1 SV=1
Length=1651
Score = 37.7 bits (86), Expect = 0.68, Method: Compositional matrix adjust.
Identities = 39/134 (29%), Positives = 58/134 (43%), Gaps = 17/134 (13%)
Query 485 NLAESKCYLITVTPVYADGPGSPESIK-AYLKQAPPSKGPTVRTKKVGKNEA-----VLE 538
+L + Y I P + + G+ IK A + PS P R+ V KN+ ++
Sbjct 740 DLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEERPSAPP--RSVTVSKNDGNGTAILVT 797
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNETAVN----VDSSHTEYTLSSLTSDTLYMVRMAA 594
W P D QNG ++ Y ++ +GNET + VD S + L Y V +AA
Sbjct 798 WQPPPEDTQNGMVQEYKVW---CLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAA 854
Query 595 YTDEGG--KDGPEF 606
T G K P+F
Sbjct 855 STGAGPGVKSEPQF 868
>sp|O46600|GHR_BOVIN Growth hormone receptor OS=Bos taurus OX=9913
GN=GHR PE=2 SV=2
Length=634
Score = 37.4 bits (85), Expect = 0.68, Method: Compositional matrix adjust.
Identities = 46/198 (23%), Positives = 81/198 (41%), Gaps = 29/198 (15%)
Query 129 PKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKF---ADCKAKRDTPTSCTVD 185
PK C E + C W G N +L+S + F D + ++ P +
Sbjct 51 PKFTKCRSPELETFSCHWTDG------ANHSLQSPGSVQMFYIRRDIQEWKECPDYVSAG 104
Query 186 YSTVYFVN--IEVW----VEAENALGKVTSDHINFDPVYKVKPNPPHNLS----VINSEE 235
++ YF + VW ++ + G V DH F V+P+PP L+ I+ E
Sbjct 105 ENSCYFNSSYTSVWTPYCIKLTSNGGIV--DHKCFSVEDIVQPDPPVGLNWTLLNISLTE 162
Query 236 LSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ + + + W P V IIL+Y + Y+ + + W + P +S + L+
Sbjct 163 IHADILVKWEPPPNTDVKMGWIILEYELHYKELNETQWKMMDP----LMVTSVPMYSLRL 218
Query 292 FTEYVFRIRCMKEDGKGY 309
EY R+R + + + Y
Sbjct 219 DKEYEVRVRTRQRNTEKY 236
>sp|Q07303|EPOR_RAT Erythropoietin receptor OS=Rattus norvegicus
OX=10116 GN=Epor PE=2 SV=1
Length=507
Score = 37.4 bits (85), Expect = 0.77, Method: Compositional matrix adjust.
Identities = 44/206 (21%), Positives = 80/206 (39%), Gaps = 18/206 (9%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY--- 186
+ L C + + C W+ + + N++ + C+ + ++ +
Sbjct 48 EELLCFTQRLEDLVCFWEEAANSGMGFNYSFSYQLEGESRKSCRLHQAPTVRGSMRFWCS 107
Query 187 ----STVYFVNIEVWV-EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
T FV +E+ V EA + HIN V + P L +EE S ++
Sbjct 108 LPTADTSSFVPLELQVTEASGSPRYHRIIHIN----EVVLLDAPAGLLARRAEEGSHVV- 162
Query 242 LTWTNPSIKSVII-LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF--R 298
L W P + ++Y + + + +Q + R+ + +L+ T Y F R
Sbjct 163 LRWLPPPGAPMTTHIRYEVDVSAGNRAGGTQR--VEVLEGRTECVLSNLRGGTRYTFAVR 220
Query 299 IRCMKEDGKGYWSDWSEEASGITYED 324
R + G+WS WSE AS +T D
Sbjct 221 ARMAEPSFSGFWSAWSEPASLLTASD 246
>sp|Q2EY14|PRTGA_DANRE Protogenin A OS=Danio rerio OX=7955 GN=prtga
PE=2 SV=1
Length=1149
Score = 37.4 bits (85), Expect = 0.79, Method: Compositional matrix adjust.
Identities = 62/287 (22%), Positives = 111/287 (39%), Gaps = 29/287 (10%)
Query 342 QGYRTVQLVW-KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLA 398
+G+ T Q+ W K P +NG+I Y +KL +N + D +
Sbjct 338 EGFPTPQITWLKNGEPVRSNGRIKMYN-----------------SKLVINQIIPEDDGIY 380
Query 399 TLTVRNLVGKSDA-AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
N+ G A A L + D + + P + + + W P + +K ++ +
Sbjct 381 QCEAENIQGSVLAMARLIVVMSDNRPSAPRNIRADTVSSSAIVLAWDRPAYNSEK-VIAY 439
Query 458 CVLSDKAPCIT--DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG--SPESIKAY 513
V KA + ++Q G Y+ +L + Y + G S I+
Sbjct 440 SVHYMKAEGLNNEEYQIVIGNDTTRYIIDDLEAGRNYTFYIVAYMPMGASRMSDHVIQHT 499
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAVNVDS 572
L+ P + P + ++ + W L + G + Y + YRT G T + + +
Sbjct 500 LEDVP-LRAPELSLTSRSPSDIQVSWQPLSHKLSRGRVSAYRLSYRTSSDGTLTQLELSA 558
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEI 618
T L L DT Y++R+AA T G G+ + TPK + ++
Sbjct 559 HKTHQLLEGLQPDTTYLLRIAAATAVGWGEPSAWSSHRTPKASSTKV 605
Score = 35.4 bits (80), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 38/174 (22%), Positives = 68/174 (39%), Gaps = 17/174 (10%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
EAEN G V + + +P+ P N+ SS + L W P+ S ++ Y+
Sbjct 383 EAENIQGSVLAMARLIVVMSDNRPSAPRNIRADTVS--SSAIVLAWDRPAYNSEKVIAYS 440
Query 259 IQYRTKDA---STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+ Y + + + DT + + + DL+ Y F I G SD
Sbjct 441 VHYMKAEGLNNEEYQIVIGNDT----TRYIIDDLEAGRNYTFYIVAYMPMGASRMSDHVI 496
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
+ T ED P +AP ++ +Q+ W+ L + G++ Y ++
Sbjct 497 QH---TLEDVPLRAPELSLT-----SRSPSDIQVSWQPLSHKLSRGRVSAYRLS 542
>sp|Q92673|SORL_HUMAN Sortilin-related receptor OS=Homo sapiens
OX=9606 GN=SORL1 PE=1 SV=2
Length=2214
Score = 37.4 bits (85), Expect = 0.79, Method: Compositional matrix adjust.
Identities = 54/218 (25%), Positives = 91/218 (42%), Gaps = 31/218 (14%)
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD 265
K SD + VYKV+ NL + + S + LTW P YN+ YR
Sbjct 1547 KACSDELT---VYKVQ-----NLQW--TADFSGDVTLTWMRPKKMPSASCVYNVYYRVVG 1596
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR--IRCMKEDGKGYWSDWSEEASGITYE 323
S W + +T S +++ ++ LKP T Y + ++C+ + + ++ + T E
Sbjct 1597 ESIWKTL---ETHSNKTNTVLKVLKPDTTYQVKVQVQCLSKA-----HNTNDFVTLRTPE 1648
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL---QNY 380
P + + P +G +V PP +G I +Y V +R S + Q
Sbjct 1649 GLPDAPRNLQLSL-PREAEGV----IVGHWAPPIHTHGLIREYIVEYSRSGSKMWASQRA 1703
Query 381 TVNATKLTVNLTNDRY---LATLTVRNLVGKSDAAVLT 415
N T++ L N Y +A +T R + SD+ +T
Sbjct 1704 ASNFTEIKNLLVNTLYTVRVAAVTSRGIGNWSDSKSIT 1741
>sp|Q2EY15|PRTG_MOUSE Protogenin OS=Mus musculus OX=10090 GN=Prtg
PE=2 SV=1
Length=1191
Score = 37.4 bits (85), Expect = 0.80, Method: Compositional matrix adjust.
Identities = 39/131 (30%), Positives = 56/131 (43%), Gaps = 14/131 (11%)
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPG------SPESIKAYLKQAPPSKGPTVRTK 528
GTVH L G L YL+ +T G G S + KA +AP K P + +
Sbjct 565 GTVHEYLLEG-LKPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAP--KSPELHLE 621
Query 529 KVGKNEAVLEWDQLPVDVQN-GFIRNYTIFYRTIIGNETA-VNVDSSHTEYTLSSLTSDT 586
+ + W Q D ++ IR Y +FY+ E + +D+ YTLS L
Sbjct 622 PLNCTTISVRWLQ---DTEDPAAIRGYKLFYKEEGQQEHGPIFLDTGDLLYTLSGLDPRR 678
Query 587 LYMVRMAAYTD 597
Y VR+ AY +
Sbjct 679 KYHVRLLAYNN 689
Score = 35.4 bits (80), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 43/176 (24%), Positives = 75/176 (43%), Gaps = 21/176 (12%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYN 258
AEN+ G V S + + +P+ P+N +++E +SS + L W P S ++ Y+
Sbjct 391 AENSQGSVLSRARLTVVMSEDRPSAPYN---VHAETMSSSAILLAWERPLYNSDKVIAYS 447
Query 259 IQYRTKDA---STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+ Y + + + DT + + + DL+P + Y F I G S S+
Sbjct 448 VHYMKAEGLNNEEYQVVLGNDT----THYIIDDLEPDSNYTFYIVAYMPLGA---SQMSD 500
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV-WKTLPPFEANGKILDYEVTL 370
+ T ED P + P S T T LV W +P G+++ Y ++
Sbjct 501 HVTQNTLEDVPLRPPEI------SLTSRSPTDILVSWLPIPAKYRRGQVVLYRLSF 550
Score = 33.9 bits (76), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 25/98 (26%), Positives = 44/98 (45%), Gaps = 6/98 (6%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV---DSSHT 575
P + P + + ++ W +P + G + Y + +R + E A+ V +
Sbjct 511 PLRPPEISLTSRSPTDILVSWLPIPAKYRRGQVVLYRLSFR--LSTENAIQVVELPGTVH 568
Query 576 EYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPK 612
EY L L D++Y+VR+ A T G G+ + TPK
Sbjct 569 EYLLEGLKPDSVYLVRITAATRVGLGESSVWTSHRTPK 606
>sp|Q9U308|JAC1_CAEEL Juxtamembrane domain-associated catenin
OS=Caenorhabditis elegans OX=6239 GN=jac-1 PE=1 SV=2
Length=1254
Score = 37.4 bits (85), Expect = 0.81, Method: Compositional matrix adjust.
Identities = 23/72 (32%), Positives = 34/72 (47%), Gaps = 4/72 (6%)
Query 242 LTWTNP--SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
L WT P + S Y ++YR + W I + + FTV+ L+P Y FR+
Sbjct 331 LEWTPPVADVHSSPPQGYQVEYRVYGSRDW--IVANEQLVQENVFTVESLRPNGVYEFRV 388
Query 300 RCMKEDGKGYWS 311
R +DG G+ S
Sbjct 389 RGKNQDGLGHPS 400
>sp|P29318|EPHA3_CHICK Ephrin type-A receptor 3 OS=Gallus gallus
OX=9031 GN=EPHA3 PE=1 SV=1
Length=983
Score = 37.4 bits (85), Expect = 0.89, Method: Compositional matrix adjust.
Identities = 46/192 (24%), Positives = 82/192 (43%), Gaps = 22/192 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW----DGGRETHLETNFTLKSEWATHKFAD-CKAK-RDT 178
PP P+N+ +NE + +W D G + N K + K + C R
Sbjct 324 PPSAPRNVISNINETSVI-LDWSWPLDTGGRKDVTFNIICKKCGGSSKICEPCSDNVRFL 382
Query 179 PTSCTVDYSTVYFV------NIEVWVEAENALGKVTSDHINFDPV-YKVKPNPPHNLSVI 231
P + +TV V N ++A N + +++ F V P ++VI
Sbjct 383 PRQTGLTNTTVTVVDLLAHTNYTFEIDAVNGVSDLSTLSRQFAAVSITTNQAAPSPITVI 442
Query 232 NSEELS-SILKLTWTNPSIKSVIILKYNIQY--RTKDASTWSQIPPEDTASTRSSFTVQD 288
+ S + + L+W P + IIL Y ++Y + + ++++ + + T + T+
Sbjct 443 RKDRTSRNSVSLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRAKST-----NVTISG 497
Query 289 LKPFTEYVFRIR 300
LKP T YVF+IR
Sbjct 498 LKPDTTYVFQIR 509
Score = 35.0 bits (79), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 30/97 (31%), Positives = 44/97 (45%), Gaps = 4/97 (4%)
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV-DSSH 574
QA PS +R + +N L W Q P + NG I +Y + Y ET+ + +
Sbjct 433 QAAPSPITVIRKDRTSRNSVSLSW-QEP-EHPNGIILDYEVKYYEKQEQETSYTILRAKS 490
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTT 610
T T+S L DT Y+ ++ A T G +F F T
Sbjct 491 TNVTISGLKPDTTYVFQIRARTAARYGTSSRKFEFET 527
Score = 34.3 bits (77), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 35/115 (30%), Positives = 49/115 (43%), Gaps = 6/115 (5%)
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
P T T ++ TV DL T Y F I + +G S S + + ++ + APS
Sbjct 383 PRQTGLTNTTVTVVDLLAHTNYTFEIDAV--NGVSDLSTLSRQFAAVSITTNQA-APSPI 439
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLT 388
I T +V L W+ P NG ILDYEV + +YT+ K T
Sbjct 440 TVIRKDRTS-RNSVSLSWQE--PEHPNGIILDYEVKYYEKQEQETSYTILRAKST 491
>sp|P16144|ITB4_HUMAN Integrin beta-4 OS=Homo sapiens OX=9606
GN=ITGB4 PE=1 SV=5
Length=1822
Score = 37.4 bits (85), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 38/151 (25%), Positives = 62/151 (41%), Gaps = 38/151 (25%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
L+++W P + + Y+++Y+ + ++ + A T S V+DL P YVFR+
Sbjct 1544 LRVSWQEPRCERPL-QGYSVEYQLLNGGELHRLNIPNPAQT--SVVVEDLLPNHSYVFRV 1600
Query 300 RCMKEDGKGYWSDWSEEASG-ITYEDR----------PSKA----------PSFWYKIDP 338
R ++G W E G IT E + P A P + + P
Sbjct 1601 RAQSQEG------WGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSP 1654
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
++QL W+ P NG I+ Y VT
Sbjct 1655 D------SLQLSWER--PRRPNGDIVGYLVT 1677
>sp|Q9QZS7|NPHN_MOUSE Nephrin OS=Mus musculus OX=10090 GN=Nphs1
PE=1 SV=2
Length=1256
Score = 37.0 bits (84), Expect = 0.96, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 51/109 (47%), Gaps = 10/109 (9%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A NALG SDH N V +P+PP L V++ S + L W P + ++ I
Sbjct 936 ATNALG---SDHTNIQLVSISRPDPPLGLKVVSVSPHS--VGLEW-KPGFDGGLPQRFQI 989
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
+Y ++ + + + + ++FT+ LKP T Y RI + + G
Sbjct 990 RYEALESPGFLYM--DVLPAQATTFTLTGLKPSTRY--RIWLLASNALG 1034
>sp|G5EBF1|SAX3_CAEEL Protein sax-3 OS=Caenorhabditis elegans
OX=6239 GN=sax-3 PE=2 SV=1
Length=1273
Score = 37.0 bits (84), Expect = 0.98, Method: Compositional matrix adjust.
Identities = 27/71 (38%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Query 240 LKLTWTNPSIKSV-IILKYNIQYRTKD-ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
++L W PS I Y IQY + D TW IP + AST + ++ LKP Y+F
Sbjct 547 VELHWNAPSTSGAGPITGYIIQYYSPDLGQTWFNIP-DYVASTE--YRIKGLKPSHSYMF 603
Query 298 RIRCMKEDGKG 308
IR E G G
Sbjct 604 VIRAENEKGIG 614
>sp|Q07498|EPHB3_CHICK Ephrin type-B receptor 3 (Fragment) OS=Gallus
gallus OX=9031 GN=EPHB3 PE=2 SV=1
Length=988
Score = 37.0 bits (84), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 29/93 (31%), Positives = 39/93 (42%), Gaps = 4/93 (4%)
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY--RTIIGNET 566
S+ QA PS PT+ N L W P + NG I +Y I Y + G+
Sbjct 416 SVNITTNQAAPSAVPTMHLHSSTGNSMTLSWT--PPERPNGIILDYEIKYSEKQGQGDGI 473
Query 567 AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
A V S L L ++ YMV++ A T G
Sbjct 474 ANTVTSQKNSVRLDGLKANARYMVQVRARTVAG 506
>sp|P13590|NCAM1_CHICK Neural cell adhesion molecule 1 OS=Gallus
gallus OX=9031 GN=NCAM1 PE=1 SV=3
Length=1091
Score = 37.0 bits (84), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 41/169 (24%), Positives = 70/169 (41%), Gaps = 19/169 (11%)
Query 176 RDTPTSCTVDYSTVYFVN------IEVWVEAENALGKVTSDHIN-----FDPVYKVKPNP 224
RD + +YS + N +EV ++EN G +N V+ +
Sbjct 440 RDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESSEFILVQADT 499
Query 225 PHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTW-SQIPPEDTASTRS 282
P + S+ E SS ++ + P + V ILKY ++R W S++ A+
Sbjct 500 PSSPSIDRVEPYSSTARVEFDEPEATGGVPILKYKAEWRALGEGEWHSRLYDAKEANVEG 559
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
+ T+ LKP T Y R+ + G G S S+ ++ +P + PS
Sbjct 560 TITISGLKPETTYSVRLSAVNGKGVGEISLPSD------FKTQPVREPS 602
>sp|A0JM20|TYRO3_XENTR Tyrosine-protein kinase receptor TYRO3
OS=Xenopus tropicalis OX=8364 GN=tyro3 PE=2 SV=1
Length=881
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 47/179 (26%), Positives = 79/179 (44%), Gaps = 32/179 (18%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS------IKSV 252
EA NA G V+S V K P PP N+++ S+ S +TW+ P IKS
Sbjct 190 EAHNAKG-VSSSRTAIVEV-KGLPYPPFNVTI--SKVTGSTATVTWS-PGFNSFSLIKSC 244
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
I ++ + S + +PP + + DL+P T + R++C E G +S+
Sbjct 245 TIQVQSLHGNREMYSRLTSVPP-------FAVVLDDLQPLTNHSVRVQCTNEMGASPFSE 297
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT---VQLVWKTLPPFEANGKILDYEV 368
W IT+ + K P ++ P + +T + L W+ + P + IL ++V
Sbjct 298 W------ITFNTK-EKVP----QLIPQNVHMTKTDSCLLLDWEDVDPDKEGYNILGFKV 345
>sp|P26221|GUN4_THEFU Endoglucanase E-4 OS=Thermobifida fusca
OX=2021 GN=celD PE=1 SV=2
Length=880
Score = 36.6 bits (83), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 24/82 (29%), Positives = 35/82 (43%), Gaps = 2/82 (2%)
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY 577
PPS + + V AVL W D + Y +F R G E V ++ T +
Sbjct 675 PPSAPGSPAVRDVTSTSAVLTW-SASSDTGGSGVAGYDVFLRAGTGQEQKVG-STTRTSF 732
Query 578 TLSSLTSDTLYMVRMAAYTDEG 599
TL+ L DT Y+ + A + G
Sbjct 733 TLTGLEPDTTYIAAVVARDNAG 754
>sp|Q8WZ75|ROBO4_HUMAN Roundabout homolog 4 OS=Homo sapiens OX=9606
GN=ROBO4 PE=1 SV=1
Length=1007
Score = 36.2 bits (82), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 34/160 (21%), Positives = 55/160 (34%), Gaps = 26/160 (16%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR----------TIIGNETAV 568
PS P T K G + W P + NG IR Y ++ T++G +T +
Sbjct 347 PSAPPQEVTLKPGNGTVFVSWVPPPAENHNGIIRGYQVWSLGNTSLPPANWTVVGEQTQL 406
Query 569 NVDSSHTEYTLSSLTSDT-------------LYMVRMAAYTDEGGKDGPEFTFTTPKFAQ 615
+ + + + T L M T E + GP +T +
Sbjct 407 EIATHMPGSYCVQVAAVTGAGAGEPSRPVCLLLEQAMERATQEPSEHGP---WTLEQLRA 463
Query 616 GEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNV 655
V+ C L LLG C ++R + H+ P +
Sbjct 464 TLKRPEVIATCGVALWLLLLGTAVCIHRRRRARVHLGPGL 503
>sp|Q2VWP7|PRTG_HUMAN Protogenin OS=Homo sapiens OX=9606 GN=PRTG
PE=2 SV=1
Length=1150
Score = 36.2 bits (82), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 40/145 (28%), Positives = 61/145 (42%), Gaps = 14/145 (10%)
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPG------SPESIKAYLKQAPPSKGPTVRTK 528
GT H L G L YL+ +T G G S + KA +AP K P + +
Sbjct 571 GTTHEYLLEG-LKPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAP--KSPELHLE 627
Query 529 KVGKNEAVLEWDQLPVDVQN-GFIRNYTIFYRTIIGNETA-VNVDSSHTEYTLSSLTSDT 586
+ + W Q DV++ I+ Y ++Y+ E + +D+ YTLS L
Sbjct 628 PLNCTTISVRWQQ---DVEDTAAIQGYKLYYKEEGQQENGPIFLDTKDLLYTLSGLDPRR 684
Query 587 LYMVRMAAYTDEGGKDGPEFTFTTP 611
Y VR+ AY + + T +TP
Sbjct 685 KYHVRLLAYNNIDDGYQADQTVSTP 709
Score = 36.2 bits (82), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 37/175 (21%), Positives = 74/175 (42%), Gaps = 19/175 (11%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYN 258
AEN+ G + S + + +P+ P+N +++E +SS + L W P S ++ Y+
Sbjct 397 AENSQGSILSRARLTVVMSEDRPSAPYN---VHAETMSSSAILLAWERPLYNSDKVIAYS 453
Query 259 IQYRTKDA---STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+ Y + + + DT + + + DL+P + Y F I G S S+
Sbjct 454 VHYMKAEGLNNEEYQVVIGNDT----THYIIDDLEPASNYTFYIVAYMPMGA---SQMSD 506
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
+ T ED P + P ++ + + W +P G+++ Y ++
Sbjct 507 HVTQNTLEDVPLRPPEISLT-----SRSPTDILISWLPIPAKYRRGQVVLYRLSF 556
Score = 34.7 bits (78), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 24/96 (25%), Positives = 42/96 (44%), Gaps = 2/96 (2%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV-NVDSSHTEY 577
P + P + + ++ W +P + G + Y + +R N V + + EY
Sbjct 517 PLRPPEISLTSRSPTDILISWLPIPAKYRRGQVVLYRLSFRLSTENSIQVLELPGTTHEY 576
Query 578 TLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPK 612
L L D++Y+VR+ A T G G+ + TPK
Sbjct 577 LLEGLKPDSVYLVRITAATRVGLGESSVWTSHRTPK 612
>sp|Q7Z7G0|TARSH_HUMAN Target of Nesh-SH3 OS=Homo sapiens OX=9606
GN=ABI3BP PE=1 SV=2
Length=1068
Score = 36.2 bits (82), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 29/95 (31%), Positives = 45/95 (47%), Gaps = 14/95 (15%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTA 278
NPP NL+V+ E S + L W P +V +I + N + K+ S
Sbjct 832 NPPTNLTVVTVEGCPSFVILDWEKPLNDTVTEYEVISRENGSFSGKNKS---------IQ 882
Query 279 STRSSF-TVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
T +F TV++LKP T Y F+++ G+G S+
Sbjct 883 MTNQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSN 917
>sp|O88786|I13R2_MOUSE Interleukin-13 receptor subunit alpha-2
OS=Mus musculus OX=10090 GN=Il13ra2 PE=1 SV=1
Length=383
Score = 35.8 bits (81), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 48/197 (24%), Positives = 77/197 (39%), Gaps = 10/197 (5%)
Query 116 YGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLK--SEWATHKF--AD 171
YGI+ G K +++ CI + + C W G+ + +TN+T+ E H AD
Sbjct 122 YGISD-EGSLETKIQDMKCIYYNWQYLVCSWKPGKTVYSDTNYTMFFWYEGLDHALQCAD 180
Query 172 CKAKRDTPTSCTV-DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
+ C + + + + + + V + L + S + F VKP PP L +
Sbjct 181 YLQHDEKNVGCKLSNLDSSDYKDFFICVNGSSKLEPIRSSYTVFQLQNIVKPLPPEFLHI 240
Query 231 INSEELSSILKLTWTNPSIK-SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
S E S +++ W+ P Y I R D S S D R + +DL
Sbjct 241 --SVENSIDIRMKWSTPGGPIPPRCYTYEIVIREDDISWESATDKNDMKLKRRANESEDL 298
Query 290 KPFTEYVFRIRCMKEDG 306
F I C +DG
Sbjct 299 CFFVRCKVNIYC-ADDG 314
>sp|P54761|EPHB4_MOUSE Ephrin type-B receptor 4 OS=Mus musculus
OX=10090 GN=Ephb4 PE=1 SV=2
Length=987
Score = 36.2 bits (82), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 29/113 (26%), Positives = 48/113 (42%), Gaps = 4/113 (4%)
Query 198 VEAENALGKVTSDHINFDPVYKV--KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
V A N + + + F+PV + PP + + S L L+W P S +L
Sbjct 406 VAALNGVSTLATGPPPFEPVNVTTDREVPPAVSDIRVTRSSPSSLILSWAIPRAPSGAVL 465
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
Y ++Y K A S + T+ R+ ++ LK Y+ ++R E G G
Sbjct 466 DYEVKYHEKGAEGPSSVRFLKTSENRAE--LRGLKRGASYLVQVRARSEAGYG 516
>sp|P13591|NCAM1_HUMAN Neural cell adhesion molecule 1 OS=Homo
sapiens OX=9606 GN=NCAM1 PE=1 SV=3
Length=858
Score = 36.2 bits (82), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 41/156 (26%), Positives = 63/156 (40%), Gaps = 19/156 (12%)
Query 176 RDTPTSCTVDYSTVYFVN------IEVWVEAENALG--------KVTSDHINFDPVYKVK 221
RD + +YS + N +EV ++EN G ++ + + F V
Sbjct 450 RDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADT 509
Query 222 PNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTW-SQIPPEDTAS 279
P+ P S+ E SS ++ + P + V ILKY ++R W S+ AS
Sbjct 510 PSSP---SIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEAS 566
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
T+ LKP T Y R+ + G G S SE
Sbjct 567 MEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASE 602
>sp|E4URG0|M28P2_ARTGP Probable zinc metalloprotease MGYG_02393
OS=Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893)
OX=535722 GN=MGYG_02393 PE=3 SV=1
Length=500
Score = 35.8 bits (81), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 28/116 (24%), Positives = 54/116 (47%), Gaps = 11/116 (9%)
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTV-YFVNIEVWVEAENALGKVTSDHI-NFD 215
FT +E H+ D + +D T + Y + F + + + +GKV + + N
Sbjct 354 FTEPNENFAHQHQDIRIDKDPKTGMDIQYGDLPEFCDFDYI----SRVGKVNAAALWNL- 408
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQ 271
+ P P N+ V N+ +L++ K TW P+ + ++ Y I +R+ +A W+
Sbjct 409 ---AMSPGMPRNVRV-NTSDLTNDSKFTWDPPAGGNALVGGYEIVWRSTNAPFWTH 460
>sp|Q568M3|CRLF3_DANRE Cytokine receptor-like factor 3 OS=Danio
rerio OX=7955 GN=crlf3 PE=2 SV=1
Length=444
Score = 35.8 bits (81), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 12/78 (15%)
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSS-FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y +Q+R ++S + ED + + F V L P +++FR+ C + +G+ WS WS
Sbjct 207 YRLQFRRSNSSQY-----EDAYIGKDTEFLVLHLDPHVDHLFRV-CARGEGRTEWSPWSI 260
Query 316 EASGITYEDRPSKAPSFW 333
+G T + AP W
Sbjct 261 PQTGYT-----TLAPHEW 273
>sp|Q96MS0|ROBO3_HUMAN Roundabout homolog 3 OS=Homo sapiens OX=9606
GN=ROBO3 PE=1 SV=2
Length=1386
Score = 36.2 bits (82), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 45/172 (26%), Positives = 71/172 (41%), Gaps = 16/172 (9%)
Query 439 LWVEWTT--PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV 496
L V WT P + V+ + + W V + T + + T LRG L I V
Sbjct 686 LQVSWTVDGPVQLVQGFRVSWRVAGPEGGSWTMLDLQSPSQQSTVLRG-LPPGTQIQIKV 744
Query 497 TPVYADGPGSPESI---KAYLKQAP--PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
+G G+ ES+ ++ ++AP P +G V G + + W+ QNG I
Sbjct 745 QAQGQEGLGA-ESLSVTRSIPEEAPSGPPQGVAVALGGDGNSSITVSWEPPLPSQQNGVI 803
Query 552 RNYTIFYRTIIGNETAVNVDSSHTEYT----LSSLTSDTLYMVRMAAYTDEG 599
Y I+ +GNE+ +++ S + L L LY +AA T G
Sbjct 804 TEYQIW---CLGNESRFHLNRSAAGWARSAMLRGLVPGLLYRTLVAAATSAG 852
>sp|Q9VS29|DSCL_DROME Cell adhesion molecule Dscam2 OS=Drosophila
melanogaster OX=7227 GN=Dscam2 PE=2 SV=3
Length=2074
Score = 36.2 bits (82), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 30/111 (27%), Positives = 51/111 (46%), Gaps = 9/111 (8%)
Query 224 PPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKD---ASTWSQIPPEDTAS 279
PP SV+ + +SS + + W ++ + + KY +++R D W QI +D
Sbjct 904 PPLPPSVLEAAMISSRSVNIKWQPKTLGTGDVTKYIVEFREADPLFVDQWQQIEVKDPPH 963
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
+ +++LKP T Y FR+ G+ S S+E T RP+ P
Sbjct 964 FNA--MIENLKPATRYAFRVIAEGSAGR---SAPSQELIVRTEPQRPAGPP 1009
Score = 35.8 bits (81), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 42/175 (24%), Positives = 67/175 (38%), Gaps = 15/175 (9%)
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKAPCITD-WQQED--GTVHRTYLRGNLAESKCYL 493
N+ W T V KYI+E+ + P D WQQ + H + NL + Y
Sbjct 922 NIKWQPKTLGTGDVTKYIVEF---READPLFVDQWQQIEVKDPPHFNAMIENLKPATRYA 978
Query 494 ITVTPVYADGPGSP--ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
V + G +P E I Q P ++ + + E ++ W ++++G I
Sbjct 979 FRVIAEGSAGRSAPSQELIVRTEPQRPAGPPLSLSARPLSSTELLISWVAPLPELRHGDI 1038
Query 552 RNYTIFYRTIIGNETAVNV-------DSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ Y + Y+ TA N D + E LS L Y V + A+ G
Sbjct 1039 QGYNVGYKLSSSGNTAYNFTSVSGDGDGGNGELLLSGLAKFARYTVVVQAFNQVG 1093
>sp|Q95209|SORL_RABIT Sortilin-related receptor OS=Oryctolagus
cuniculus OX=9986 GN=SORL1 PE=1 SV=1
Length=2213
Score = 36.2 bits (82), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 23/92 (25%), Positives = 42/92 (46%), Gaps = 7/92 (8%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P+ P NL + E ++ W+ P+ +I +Y ++Y + W+ +
Sbjct 1650 PDAPQNLQLSLHGEEEGVIVGHWSPPTHTHGLIREYIVEYSRSGSKVWT------SERAA 1703
Query 282 SSFT-VQDLKPFTEYVFRIRCMKEDGKGYWSD 312
S+FT +++L T Y R+ + G G WSD
Sbjct 1704 SNFTEIKNLLVNTLYTVRVAAVTSRGIGNWSD 1735
>sp|P08922|ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS
OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3
Length=2347
Score = 36.2 bits (82), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 44/175 (25%), Positives = 69/175 (39%), Gaps = 16/175 (9%)
Query 240 LKLTWTNPSIKSVIILKYNIQYR-TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ L W + + V KY IQ++ + +W+ +R S+ V+ L PFTEY+FR
Sbjct 115 MTLRWKSANFSGV---KYIIQWKYAQLLGSWTY----TKTVSRPSYVVKPLHPFTEYIFR 167
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+ + +S S +Y P P I + TV++ W PP
Sbjct 168 VVWIFTAQLQLYSPPSP-----SYRTHPHGVPETAPLIRNIESSSPDTVEVSWD--PPQF 220
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNAT-KLTVNLTNDRYLATLTVRNLVGKSDAA 412
G IL Y + L L T + + L N Y ++ N VG+ A
Sbjct 221 PGGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTIYRFSIAAVNEVGEGPEA 275
>sp|Q8IWZ5|TRI42_HUMAN Tripartite motif-containing protein 42
OS=Homo sapiens OX=9606 GN=TRIM42 PE=1 SV=2
Length=723
Score = 35.8 bits (81), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 13/32 (41%), Positives = 22/32 (69%), Gaps = 0/32 (0%)
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ + + +L P TEYVF++R + ++G G WSD
Sbjct 661 QQNLELHNLTPNTEYVFKVRAINDNGPGQWSD 692
>sp|P32927|IL3RB_HUMAN Cytokine receptor common subunit beta OS=Homo
sapiens OX=9606 GN=CSF2RB PE=1 SV=2
Length=897
Score = 35.8 bits (81), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 24/64 (38%), Positives = 31/64 (48%), Gaps = 4/64 (6%)
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY--VFRIRCMKEDGKGYWSDWS 314
+ IQYR KD +TW E T S + L+P T Y R+R + G WS+WS
Sbjct 372 FEIQYR-KDTATWKDSKTE-TLQNAHSMALPALEPSTRYWARVRVRTSRTGYNGIWSEWS 429
Query 315 EEAS 318
E S
Sbjct 430 EARS 433
>sp|P24394|IL4RA_HUMAN Interleukin-4 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL4R PE=1 SV=1
Length=825
Score = 35.8 bits (81), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 42/182 (23%), Positives = 65/182 (36%), Gaps = 42/182 (23%)
Query 169 FADCKAKRDTPTSCTVD----YSTVYFVNIEVWVEAENALGKVTSDHI------------ 212
+ C+ K + PT+C+ + Y V+ ++ EN G H+
Sbjct 41 ISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYT 100
Query 213 -------------NFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
+F P VKP P NL+V + +S L LTW+NP Y
Sbjct 101 LDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTN--VSDTLLLTWSNPYPPD----NYLY 154
Query 260 QYRTKDASTWSQIPPEDTASTRSSF-------TVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ T + WS+ P D ++ LK Y R+R + WS+
Sbjct 155 NHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSE 214
Query 313 WS 314
WS
Sbjct 215 WS 216
>sp|Q02388|CO7A1_HUMAN Collagen alpha-1(VII) chain OS=Homo sapiens
OX=9606 GN=COL7A1 PE=1 SV=2
Length=2944
Score = 35.8 bits (81), Expect = 2.4, Method: Composition-based stats.
Identities = 41/150 (27%), Positives = 61/150 (41%), Gaps = 9/150 (6%)
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL-KQAPPSKGPTVRTKKVGKN 533
G +RG L Y + VT + D G+P SI +APP+ G T+ + G++
Sbjct 824 GNTDSAEIRG-LEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALG-TLHVVQRGEH 881
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
L W+ PV GF+ + ++ G E + + + Y L L T Y VR++
Sbjct 882 SLRLRWE--PVPRAQGFL----LHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRVRLS 935
Query 594 AYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
G E T T IE VV
Sbjct 936 VLGPAGEGPSAEVTARTESPRVPSIELRVV 965
>sp|P11627|L1CAM_MOUSE Neural cell adhesion molecule L1 OS=Mus
musculus OX=10090 GN=L1cam PE=1 SV=1
Length=1260
Score = 35.8 bits (81), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 45/198 (23%), Positives = 81/198 (41%), Gaps = 25/198 (13%)
Query 438 MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITV 496
+ W++W P+ +Y ++W + W+++ TV +L N + Y I V
Sbjct 737 LRWMDWNAPQ---IQYRVQWRPQGKQE----TWRKQ--TVSDPFLVVSNTSTFVPYEIKV 787
Query 497 TPVYADGPG-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVL-EWDQLPVDVQNGFIRNY 554
V G G P+ Y + P P + + + VL W + + G ++ Y
Sbjct 788 QAVNNQGKGPEPQVTIGYSGEDYPQVSPELEDITIFNSSTVLVRWRPVDLAQVKGHLKGY 847
Query 555 TIFY-----------RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ Y R I +++ + V ++ T LS L + Y V + A+ G
Sbjct 848 NVTYWWKGSQRKHSKRHI--HKSHIVVPANTTSAILSGLRPYSSYHVEVQAFNGRGLGPA 905
Query 604 PEFTFTTPKFAQGEIEAI 621
E+TF+TP+ G EA+
Sbjct 906 SEWTFSTPEGVPGHPEAL 923
Score = 34.7 bits (78), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 41/155 (26%), Positives = 68/155 (44%), Gaps = 22/155 (14%)
Query 222 PNPPHNLSVINSEEL-SSILKLTWTNPSIKSVIILKYNIQYRTKDAS-----TWSQIPPE 275
P P +L + + L S + L+W+ + I KY+I++ K+ + + ++P
Sbjct 611 PGPVPHLELSDRHLLKQSQVHLSWSPAEDHNSPIEKYDIEFEDKEMAPEKWFSLGKVPGN 670
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
T++T L P+ Y FR+ + + G G S SE S +T E P K P
Sbjct 671 QTSTTLK------LSPYVHYTFRVTAINKYGPGEPSPVSE--SVVTPEAAPEKNP----- 717
Query 336 IDPSHTQGYRTVQLV--WKTLPPFEANGKILDYEV 368
+D +G T +V WK L + N + Y V
Sbjct 718 VD-VRGEGNETNNMVITWKPLRWMDWNAPQIQYRV 751
>sp|P34082|FAS2_DROME Fasciclin-2 OS=Drosophila melanogaster OX=7227
GN=Fas2 PE=1 SV=1
Length=873
Score = 35.8 bits (81), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 22/63 (35%), Positives = 29/63 (46%), Gaps = 11/63 (17%)
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRS-----SFTVQDLKPFTEYVFRIRCMKEDGKG 308
IL Y++QY+ WS TA RS + V+ L+P TEY FR + G G
Sbjct 556 ILAYSVQYKEALNPDWS------TAYNRSWSPDSPYIVEGLRPQTEYSFRFAARNQVGLG 609
Query 309 YWS 311
W
Sbjct 610 NWG 612
>sp|H2KZ60|RIG6_CAEEL Contactin rig-6 OS=Caenorhabditis elegans
OX=6239 GN=rig-6 PE=1 SV=1
Length=1196
Score = 35.8 bits (81), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 86/396 (22%), Positives = 145/396 (37%), Gaps = 73/396 (18%)
Query 257 YNIQYRTKDASTWSQIPPEDTAST-RSSFTVQDLKPFTEYVFRIRCMKEDGKG---YWSD 312
Y ++ RT+ W + + + S TV++L P TEY FR+R ++ G SD
Sbjct 778 YLVELRTRKNRKWRAAERQLVGNMEKDSITVENLLPNTEYQFRVRSVESAAIGEPSIPSD 837
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP-PFEANGKILDYEVTLT 371
W + A G E + W +D +T+ + W+ + E++G L Y V+ +
Sbjct 838 WVKTAPGAPSETIDNLK---WRSLDS------QTLLVEWQPIEIGQESSGDNLRYRVSWS 888
Query 372 R-------------------WKSHLQNYTVNATKLTVNLTNDRYLATLTVR--NLVGKSD 410
+++HL + A L +N T + L VR N G
Sbjct 889 EATVGKNATDDMKLSNQDDDFENHLDSDQPQAI-LKLNTTEGCRMVVLAVRPVNDQGNGS 947
Query 411 AAVLTIPACDFQ------ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
TI + + H V + A N+ W W + K+ ++ ++
Sbjct 948 VGTDTIAFLNSHGELKKVSLHNVKPINA-SHVNISWT-WDNTSDCDTKHAVQITCINLSG 1005
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES--IKAYLKQAPPSKG 522
I+ D ++ G L Y + + G P S + + KQ PPS+
Sbjct 1006 SEISATVASDRIF---WMLGGLEAETAYDCDLKAIDNHGSFGPASKKFRIHTKQHPPSET 1062
Query 523 PTVRTKKVGKNE----AVLEWD----QLPVDVQNGFIRNYTIFYRTIIGNETAVNV---- 570
P + + + + +LEW Q P +NG Y IF I +ETA
Sbjct 1063 PLIGKLMMKQMKDTYTTILEWSSIELQKPNRTENGC--GYKIF---IYISETATEAIELD 1117
Query 571 -------DSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
D + L L +Y +++A Y G
Sbjct 1118 MPLQRLSDRRNPSARLDGLKLMYMYTIKVAGYNPGG 1153
>sp|P29294|MYLK_RABIT Myosin light chain kinase, smooth muscle
OS=Oryctolagus cuniculus OX=9986 GN=MYLK PE=1 SV=2
Length=1147
Score = 35.8 bits (81), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 39/128 (30%), Positives = 60/128 (47%), Gaps = 14/128 (11%)
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNI 259
EN LG + +N V K P+PP S+ SS L L+W S + Y++
Sbjct 544 ENKLGSRQA-QVNLTVVDK--PDPPAGTPCA-SDIRSSSLTLSWYGSSYDGGSAVQSYSV 599
Query 260 QYRTKDASTWSQIPPEDTASTRS-SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+ W+++ A+ RS SF V+DL P EY FR+R + G S+ S+E+
Sbjct 600 EIWDSVDKMWTEL-----ATCRSTSFNVRDLLPDREYKFRVRAINVYGT---SEPSQESE 651
Query 319 GITYEDRP 326
T ++P
Sbjct 652 LTTVGEKP 659
>sp|P20241|NRG_DROME Neuroglian OS=Drosophila melanogaster OX=7227
GN=Nrg PE=1 SV=2
Length=1302
Score = 35.4 bits (80), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 52/199 (26%), Positives = 77/199 (39%), Gaps = 24/199 (12%)
Query 230 VINSEELSSI------LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
V N+ +L+ I ++ W IL Y IQ+ T E +T SS
Sbjct 614 VPNAPKLTGITCQADKAEIHWEQQGDNRSPILHYTIQFNTSFTPASWDAAYEKVPNTDSS 673
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
F VQ + P+ Y FR+ + G S S+ S T D P K P D QG
Sbjct 674 FVVQ-MSPWANYTFRVIAFNKIGASPPSAHSD--SCTTQPDVPFKNP------DNVVGQG 724
Query 344 YRTVQLV--WKTLPPFEANGKILDYEVTLTR------WK-SHLQNYTVNATKLTVNLTND 394
LV W +P E N Y V+ R W+ +++ ++ N + T
Sbjct 725 TEPNNLVISWTPMPEIEHNAPNFHYYVSWKRDIPAAAWENNNIFDWRQNNIVIADQPTFV 784
Query 395 RYLATLTVRNLVGKSDAAV 413
+YL + N G+S+ A
Sbjct 785 KYLIKVVAINDRGESNVAA 803
>sp|Q95JF2|GHR_AILME Growth hormone receptor OS=Ailuropoda melanoleuca
OX=9646 GN=GHR PE=2 SV=1
Length=638
Score = 35.4 bits (80), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 50/226 (22%), Positives = 89/226 (39%), Gaps = 36/226 (16%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLK--------SEWATHKFADCKAKR 176
P KP+ C E + C W G ++ +++ EW T ++ +C
Sbjct 47 PSGKPQFTKCRSPELETFSCHWTEGVHHGVKNPGSIQLFYIRRSTQEW-TPEWKEC---- 101
Query 177 DTPTSCTVDYSTVYFVN--IEVWVEAENAL--GKVTSDHINFDPVYKVKPNPPHNLS--- 229
P + ++ YF + +W+ L T D F V+P+PP L+
Sbjct 102 --PDYVSAGENSCYFNSSYTSIWIPYCIKLTSNGDTVDQKCFSVEEIVQPDPPIGLNWTL 159
Query 230 -VINSEELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
I+ + + +++ W P V I+L+Y +QY+ + S W + P +S
Sbjct 160 LNISLTGIHADIQVRWEPPPNADVQKGWIVLEYELQYKEVNESQWKMMDP----VLSTSV 215
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
V L+ EY R+R + + + Y E S + Y P +P
Sbjct 216 PVYSLRLDKEYEVRVRSRQRNSEKY-----GEFSEVLYVALPQMSP 256
>sp|O94856|NFASC_HUMAN Neurofascin OS=Homo sapiens OX=9606 GN=NFASC
PE=1 SV=4
Length=1347
Score = 35.4 bits (80), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 41/146 (28%), Positives = 59/146 (40%), Gaps = 18/146 (12%)
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
R V L P++ Y + + G G SE T E PS AP + P+
Sbjct 890 RLRGVVSRLFPYSNYKLEMVVVNGRGDG---PRSETKEFTTPEGVPS-APRRFRVRQPN- 944
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW------KSHLQNYTVNATKLTVNLTN- 393
T+ L W P NG ++ Y + + K ++N++ N TK TV T+
Sbjct 945 ---LETINLEWDH--PEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDP 999
Query 394 -DRYLATLTVRNLVGKSDAAVLTIPA 418
RY TL+ R VG +A PA
Sbjct 1000 VSRYRFTLSARTQVGSGEAVTEESPA 1025
>sp|P13596|NCAM1_RAT Neural cell adhesion molecule 1 OS=Rattus
norvegicus OX=10116 GN=Ncam1 PE=1 SV=1
Length=858
Score = 35.4 bits (80), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 41/172 (24%), Positives = 73/172 (42%), Gaps = 25/172 (15%)
Query 176 RDTPTSCTVDYSTVYFVN------IEVWVEAENALG--------KVTSDHINFDPVYKVK 221
RD + +YS + N +EV ++EN G ++ + + F V
Sbjct 451 RDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADT 510
Query 222 PNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTW-SQIPPEDTAS 279
P+ P S+ E SS ++ + P + V ILKY ++++ W S+ A+
Sbjct 511 PSSP---SIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLGEEAWHSKWYDAKEAN 567
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
T+ LKP T Y R+ + +GKG E ++ ++ +P + PS
Sbjct 568 MEGIVTIMGLKPETRYAVRLAAL--NGKGL----GEISAATEFKTQPVREPS 613
>sp|P36335|NCA12_XENLA Neural cell adhesion molecule 1-B OS=Xenopus
laevis OX=8355 GN=ncam1-b PE=2 SV=1
Length=1092
Score = 35.4 bits (80), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 32/130 (25%), Positives = 55/130 (42%), Gaps = 7/130 (5%)
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINF-----DPVYKVKPNPPHNLSVINSEELSSIL 240
Y+ F ++EV ++EN G +N V+ + P + ++ E SS +
Sbjct 450 YNGPTFSSLEVNPDSENDFGNYNCSAVNSIGHESSEFILVQADTPSSPAIRKVEPYSSTV 509
Query 241 KLTWTNP-SIKSVIILKYNIQYRTKDASTW-SQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ + P + V ILKY ++R W ++ S S TV LKP T Y+ +
Sbjct 510 MIVFDEPDATGGVPILKYKAEWRVVGQEKWHARYYDAKEVSAESIITVTGLKPETSYMVK 569
Query 299 IRCMKEDGKG 308
+ + G G
Sbjct 570 LSAVNGKGLG 579
>sp|Q9Z2L7|CRLF3_MOUSE Cytokine receptor-like factor 3 OS=Mus
musculus OX=10090 GN=Crlf3 PE=1 SV=1
Length=442
Score = 35.0 bits (79), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 18/63 (29%), Positives = 31/63 (49%), Gaps = 5/63 (8%)
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y +Q+R A+ + + + + F V + P +Y FR+ C + DG+ WS WS
Sbjct 211 YRLQFRKCTANHFEDV----YVGSETEFIVLHIDPNVDYQFRV-CARGDGRQEWSPWSVP 265
Query 317 ASG 319
+G
Sbjct 266 QTG 268
>sp|Q863Z5|IL4RA_PIG Interleukin-4 receptor subunit alpha OS=Sus
scrofa OX=9823 GN=IL4R PE=2 SV=1
Length=830
Score = 35.0 bits (79), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 52/232 (22%), Positives = 80/232 (34%), Gaps = 42/232 (18%)
Query 131 NLSCIV---NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
++SC++ G + C GG LE L +T + C+ + P +C+ ++
Sbjct 11 SVSCLILVWAAGSGVTCVSPGGVRV-LEWPICLSDYVST---STCEWRMAGPVNCSAEFR 66
Query 188 TVY---FVNIE--VWVEAENALGKVTSDHI-------------------------NFDPV 217
Y F N E EN G V H+ +F P
Sbjct 67 LSYQLKFFNTENHTTCVPENRAGSVCVCHMLMESIVIVDTYQLDLWAGEQLLWNSSFKPS 126
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII---LKYNIQYRTKDASTWSQIPP 274
VKP P NL V +S LTW+NP + L Y + ++ T +I
Sbjct 127 QNVKPLAPRNLMV--HANISHTWLLTWSNPYPSESYLYSELTYLVNISNENDPTDFRIYN 184
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
F LK Y R++ + WS+WS + Y + P
Sbjct 185 VTYLGPTLRFPANTLKSGAAYSARVKAWAQRYNSTWSEWSPSVKWLNYYEEP 236
>sp|Q9Y2H6|FND3A_HUMAN Fibronectin type-III domain-containing
protein 3A OS=Homo sapiens OX=9606 GN=FNDC3A PE=1 SV=4
Length=1198
Score = 35.0 bits (79), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 20/75 (27%), Positives = 36/75 (48%), Gaps = 9/75 (12%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
S+ L ++W P IL Y+I + K + T ++ +S+ + +L+P T Y
Sbjct 875 STCLAISWEKPCDHGSEILAYSIDFGDKQSLTVGKV---------TSYIINNLQPDTTYR 925
Query 297 FRIRCMKEDGKGYWS 311
RI+ + G G +S
Sbjct 926 IRIQALNSLGAGPFS 940
Score = 35.0 bits (79), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 52/211 (25%), Positives = 80/211 (38%), Gaps = 29/211 (14%)
Query 181 SCTVDYSTVYFVN-------IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS 233
S TV T Y +N + ++A N+LG H+ + P+PP V S
Sbjct 904 SLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPRLECVAFS 963
Query 234 EELSSILKLTWTN--PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ LKL W P S ++Y++Q K+ S ++ VQ L
Sbjct 964 HQ---NLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLY-----RGPCHTYKVQRLNE 1015
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS--KAPSFWYKIDPSHTQGYRTVQL 349
T Y F I+ E G+G S+E T + P+ KAP D ++
Sbjct 1016 STSYKFCIQACNEAGEG---PLSQEYIFTTPKSVPAALKAPKIEKVND-------HICEI 1065
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNY 380
W+ L P + + I +V L + Q Y
Sbjct 1066 TWECLQPMKGDPVIYSLQVMLGKDSEFKQIY 1096
>sp|O00533|NCHL1_HUMAN Neural cell adhesion molecule L1-like protein
OS=Homo sapiens OX=9606 GN=CHL1 PE=1 SV=4
Length=1208
Score = 35.0 bits (79), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 67/314 (21%), Positives = 122/314 (39%), Gaps = 43/314 (14%)
Query 83 NRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKM 142
N T S+VT D C+ T ++ +T++ P+ P+NL + + +
Sbjct 575 NLTISNVTLEDQGIY----CCSAHTALDSAADITQVTVLD--VPDPPENLHLSERQNRSV 628
Query 143 RCEWDGGRE---------THLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN 193
R W+ G + E N W + + K+ TV FV
Sbjct 629 RLTWEAGADHNSNISEYIVEFEGNKEEPGRW--EELTRVQGKK-----TTVILPLAPFVR 681
Query 194 IEVWVEAENALGKVT----SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+ V A N +G+ SDH P + P N+ V S+ I+K
Sbjct 682 YQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRN--PQNIRVQASQPKEMIIKWEPLKSME 739
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP--FTEYVFRIRCMKEDGK 307
++ L+Y + ++ + A P E T ++ T++ + P + Y +++ + + G
Sbjct 740 QNGPGLEYRVTWKPQGA------PVEWEEETVTNHTLRVMTPAVYAPYDVKVQAINQLGS 793
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
G SG ED P AP + +D ++ V++ W T+P +G++ Y+
Sbjct 794 GPDPQSVTLYSG---EDYPDTAPVI-HGVDVINST---LVKVTWSTVPKDRVHGRLKGYQ 846
Query 368 VTLTRWKSHLQNYT 381
+ + KS L T
Sbjct 847 INWWKTKSLLDGRT 860
>sp|Q28575|GHR_SHEEP Growth hormone receptor OS=Ovis aries OX=9940
GN=GHR PE=2 SV=1
Length=634
Score = 35.0 bits (79), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 44/193 (23%), Positives = 79/193 (41%), Gaps = 29/193 (15%)
Query 134 CIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKF---ADCKAKRDTPTSCTVDYSTVY 190
C E + C W G N +L+S + F D + ++ P + ++ Y
Sbjct 56 CRSPELETFSCHWTDG------ANHSLQSPGSVQMFYIRRDIQEWKECPDYVSAGENSCY 109
Query 191 FVN--IEVW----VEAENALGKVTSDHINFDPVYKVKPNPPHNLS----VINSEELSSIL 240
F + VW ++ + G V DH F V+P+PP L+ I+ E+ + +
Sbjct 110 FNSSYTSVWTPYCIKLTSNGGIV--DHKCFSVEDIVQPDPPVGLNWTLLNISLTEIHADI 167
Query 241 KLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
+ W P V IIL+Y + Y+ + + W + P +S + L+ EY
Sbjct 168 LVKWEPPPNTDVKMGWIILEYELHYKELNETQWKMMDP----LLVTSVPMYSLRLDKEYE 223
Query 297 FRIRCMKEDGKGY 309
R+R + + + Y
Sbjct 224 VRVRTRQRNTEKY 236
>sp|Q6DFV6|FN3C1_MOUSE Fibronectin type III domain containing
protein 3C1 OS=Mus musculus OX=10090 GN=Fndc3c1 PE=2 SV=1
Length=1356
Score = 35.0 bits (79), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 8/84 (10%)
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
VQ L +TEY F+I+ E G+G SD Y +K+P K H
Sbjct 1163 VQKLSEYTEYKFKIQACNEAGEGPESD--------IYTFTTTKSPPTALKAPKVHPLNNN 1214
Query 346 TVQLVWKTLPPFEANGKILDYEVT 369
+ ++ W++L P + + + +VT
Sbjct 1215 SCEIKWESLEPIKGDPIVYCLQVT 1238
Score = 34.3 bits (77), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 30/134 (22%), Positives = 56/134 (42%), Gaps = 18/134 (13%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
S+ + + W P I YNI+Y K T +I + + ++DL+P T Y
Sbjct 1028 STCIAIRWEEPDCHGSPITGYNIEYGDKKVVTVKRI---------TEYVLKDLQPNTTYR 1078
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
RI+ + G S +S T + P + P + G+++++L W T+
Sbjct 1079 IRIQAINHYG---LSPFSPSIRCKT-KPLPPEPPQLNCVV-----YGHQSLRLKWGTVSS 1129
Query 357 FEANGKILDYEVTL 370
+ ++Y V +
Sbjct 1130 KKTLANFINYNVLM 1143
>sp|Q8K9T7|DLDH_BUCAP Dihydrolipoyl dehydrogenase OS=Buchnera
aphidicola subsp. Schizaphis graminum (strain Sg) OX=198804
GN=lpdA PE=3 SV=1
Length=476
Score = 34.7 bits (78), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 26/89 (29%), Positives = 38/89 (43%), Gaps = 14/89 (16%)
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
+E SG + P PS Y DP ++ W L EA +DYEV+L W
Sbjct 333 AEVISGKKHYFEPKVIPSVAYT-DP---------EIAWVGLSEKEAENNDIDYEVSLFPW 382
Query 374 ----KSHLQNYTVNATKLTVNLTNDRYLA 398
++H N T+ TKL N ++ +
Sbjct 383 SASGRAHASNCTLGMTKLIFNKNTNKIIG 411
>sp|Q9U4G1|BDL_DROME Protein borderless OS=Drosophila melanogaster
OX=7227 GN=bdl PE=1 SV=1
Length=719
Score = 35.0 bits (79), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 7/95 (7%)
Query 217 VYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPED 276
+ + P P+NL+ ++E + + + W ++ L+Y + YR +A W + D
Sbjct 430 IENIAPRAPYNLTANSTE---TCITIRWQPGYLRPN--LEYTVWYRLMEAPEWRTLRVLD 484
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+ TVQ L+P EY F + + G G +S
Sbjct 485 KKVMEA--TVQHLQPGKEYEFMVLSQDKYGDGMFS 517
>sp|Q6NWW9|FND3B_MOUSE Fibronectin type III domain-containing
protein 3B OS=Mus musculus OX=10090 GN=Fndc3b PE=1 SV=1
Length=1207
Score = 35.0 bits (79), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 12/100 (12%)
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS--KAPSFWYKIDPSH 340
++ VQ L FT Y FRI+ M E G+G +SE + T + P KAP +
Sbjct 1017 TYKVQRLTEFTCYSFRIQAMSEAGEG---PYSETYTFSTTKSVPPTLKAPRV------TQ 1067
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY 380
+G + ++ W+T+PP + +V + R + Q Y
Sbjct 1068 LEG-NSCEIFWETVPPMRGDPVSYVLQVLVGRDSEYKQVY 1106
Score = 34.7 bits (78), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 77/339 (23%), Positives = 118/339 (35%), Gaps = 51/339 (15%)
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
++DL+P T+Y R+ + KG SE S T+ S AP + +H +
Sbjct 345 LKDLRPATDYHVRVYAVYNSVKG---SCSEPVSFTTH----SCAPECPFPPKLAH-RSKS 396
Query 346 TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA--------TKLTVNLTNDRYL 397
++ L WK P + KI Y L W +N KLT Y
Sbjct 397 SLTLQWKA--PIDNGSKITSY---LLEWDEGKRNSGFRQCFFGSQKHCKLTKLCPAMGYT 451
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA-FPKDNMLWV--EWTTPRESVKKYI 454
L RN +G S + + C P M L + + W+ +W+ P + +
Sbjct 452 FRLAARNDIGTSGYSQEVV--CYTLGNIPQMPLAPRLVRAGVTWITLQWSRPEGCSPEEV 509
Query 455 LEWCVLSDKAPCITDWQQEDGTVH---------RTYLRGNLAESKCYLITVTPVYADGPG 505
+ + + D Q+++ H T NL S Y +T +G
Sbjct 510 ITYTL---------DIQEDENDSHFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNMEGKS 560
Query 506 SPESIKAYLKQAPPSKGPTVR---TKKVGKNEAVLEWDQLPVDVQNGFIRNYT--IFYRT 560
P + +P GP R V + ++WD P D I Y I T
Sbjct 561 CPSEVLV-CTTSPDRPGPPTRPLIKGPVTSHGFSVKWDA-PKDNGGSEIPKYLLEITDGT 618
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ V S TEY + L TLY +R + G
Sbjct 619 PEAGQWEVAYSGSATEYVFTHLKPGTLYKLRACCISTGG 657
>sp|Q9I7U4|TITIN_DROME Titin OS=Drosophila melanogaster OX=7227
GN=sls PE=1 SV=3
Length=18141
Score = 35.0 bits (79), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 101/475 (21%), Positives = 180/475 (38%), Gaps = 96/475 (20%)
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK-- 221
W T K K+KR PT +D + +V + E G+ T +N PV + +
Sbjct 17312 WTTRKVVIPKSKRTIPT---IDEQSAKLTIKKVVDDDE---GEYTVKLVN--PVGEAEAS 17363
Query 222 -----------PNPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDAST 268
P P L +++ + L W P KS II +Y ++Y+
Sbjct 17364 LHLVIMRKPTAPGTPQPLEIMHDS-----ITLYWKAPEDDGKSEII-EYILEYQDVKEEK 17417
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
W++I +++T+ LK TEYVFR + E G S S + + +K
Sbjct 17418 WTEI----RKIKDTTYTISKLKIDTEYVFRSIAVNEVGPSPPSPLSPPIRLVPKVE--TK 17471
Query 329 APSFWYKIDPSHTQGYRTVQL--VWKTLPP----FEANGKILDYEVTLTRWKSHLQNYTV 382
APS + ++ + V L V+ +P ++ NG++ +E R+++ + YT+
Sbjct 17472 APSVQEPLQDVVSELDKEVTLSCVFGGIPEPKVTWKKNGQV--FESRSIRYENRVAKYTI 17529
Query 383 NATKL------TVNLTNDRYLATLTVRNLVGKS---------------DAAVLTIPACDF 421
T + T TN++ A + R + + ++LTIPA
Sbjct 17530 EKTTIETEATYTCVATNEKGSAETSCRLKLQQKPVLEVEDKYLTQKLRTGSILTIPAT-- 17587
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
++ +P+ + W + T +++ K +E + +++ G Y
Sbjct 17588 --------VRGYPQPTVTWHKETIEQKTTKSVTIETTETTSTYTVKKVTREQSG----KY 17635
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
ES + T D P P+S++ K + K+ VLEW
Sbjct 17636 KVTATNESGTTYVECTVQVIDKPSRPQSLE---------------IKDIKKDSIVLEWTP 17680
Query 542 LPVDVQNGFIRNYTIFYRTIIGN--ETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
PVD I YT+ + N + + Y + L+ + YM R+ A
Sbjct 17681 -PVDDGGLDIEKYTLEKCDVQNNVWMKVSDFNKDIKSYAVQKLSMNAQYMFRVVA 17734
>sp|Q80W87|ROBO4_RAT Roundabout homolog 4 OS=Rattus norvegicus
OX=10116 GN=Robo4 PE=2 SV=1
Length=961
Score = 35.0 bits (79), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 8/88 (9%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET--AVN--VDSSH 574
PS P T + G + W P + NGFIR Y ++ +GN + A N V
Sbjct 358 PSAPPQEVTLRPGNGSVFVSWAPPPAENHNGFIRGYQVWS---LGNASLPAANWTVVGEQ 414
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
T+ +++ + Y V++AA T G +
Sbjct 415 TQLEIAARMPGS-YCVQVAAVTGAGAGE 441
>sp|Q5RBN1|FND3A_PONAB Fibronectin type-III domain-containing
protein 3A OS=Pongo abelii OX=9601 GN=FNDC3A PE=2 SV=1
Length=1142
Score = 34.7 bits (78), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 52/211 (25%), Positives = 80/211 (38%), Gaps = 29/211 (14%)
Query 181 SCTVDYSTVYFVN-------IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS 233
S TV T Y +N + ++A N+LG H+ + P+PP V S
Sbjct 848 SLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHVIKLKTKPLPPDPPRLECVAFS 907
Query 234 EELSSILKLTWT--NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ LKL W P S ++Y++Q K+ S ++ VQ L
Sbjct 908 HQ---NLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLY-----RGPCHTYKVQRLNE 959
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS--KAPSFWYKIDPSHTQGYRTVQL 349
T Y F I+ E G+G S+E T + P+ KAP D ++
Sbjct 960 STSYKFCIQACNEAGEG---PVSQEYIFTTPKSVPAALKAPKIEKVND-------HICEI 1009
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNY 380
W+ L P + + I +V L + Q Y
Sbjct 1010 TWECLQPMKGDPVIYSLQVMLGKDSEFKQIY 1040
>sp|Q98930|SORL_CHICK Sortilin-related receptor (Fragment) OS=Gallus
gallus OX=9031 GN=SORL1 PE=2 SV=1
Length=1592
Score = 34.7 bits (78), Expect = 5.0, Method: Compositional matrix adjust.
Identities = 19/66 (29%), Positives = 31/66 (47%), Gaps = 3/66 (5%)
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ S + LTW P S YN+ YR S W + +T S ++S ++ LKP
Sbjct 1472 DFSGAITLTWARPKRMSSTSCVYNVYYRMVGESIWKVL---ETHSNKTSSVLKVLKPDCT 1528
Query 295 YVFRIR 300
Y +++
Sbjct 1529 YQVKVQ 1534
>sp|Q90Z04|CDON_XENLA Cell adhesion molecule-related/down-regulated
by oncogenes OS=Xenopus laevis OX=8355 GN=cdon PE=2 SV=1
Length=1249
Score = 34.7 bits (78), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 22/86 (26%), Positives = 44/86 (51%), Gaps = 5/86 (6%)
Query 522 GPTV-RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR-TIIGNETAVN---VDSSHTE 576
GP + +T+ V + +L+W +P + N I+ + I+YR T N++ V+ +
Sbjct 826 GPRIDQTEAVTDTQILLKWTYIPENNNNTPIQGFYIYYRPTDSDNDSDYKRDMVEGTKLR 885
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ +S L +T Y ++M + + G D
Sbjct 886 HLISHLQPETSYDIKMQCFNERGASD 911
>sp|G5EC23|HCF1_CAEEL Host cell factor homolog hcf-1 OS=Caenorhabditis
elegans OX=6239 GN=hcf-1 PE=1 SV=1
Length=782
Score = 34.7 bits (78), Expect = 5.3, Method: Compositional matrix adjust.
Identities = 35/95 (37%), Positives = 42/95 (44%), Gaps = 15/95 (16%)
Query 282 SSFTVQDLKPFTE---YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
S FT +D P Y FR+ + GKG WS E AS T APS +I
Sbjct 596 SVFTTEDKIPLINGQSYRFRVSAINGLGKGAWS---ETASCKTCVPGYPSAPSS-IRITK 651
Query 339 SHTQGYRTVQLVWKTLPPFEAN--GKILDYEVTLT 371
SH QL W+ PP N GKI++Y V L
Sbjct 652 SH----EGAQLTWE--PPSNTNISGKIIEYSVYLA 680
>sp|Q6YI48|PTPRU_CHICK Receptor-type tyrosine-protein phosphatase
U OS=Gallus gallus OX=9031 GN=PTPRU PE=2 SV=1
Length=1434
Score = 34.7 bits (78), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 29/124 (23%), Positives = 56/124 (45%), Gaps = 9/124 (7%)
Query 504 PGSPESIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII 562
PG P + + K A P + P + ++ + L+W+ L ++ + ++ YR ++
Sbjct 369 PGPP--LISRTKCAEPMRAPKGLAFSEIQSRQLTLQWEPLGYNLTRCHTYSVSLCYRYLV 426
Query 563 G---NET---AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
G N+T ++ + YT+ +L V++ EG K+G E TF T + G
Sbjct 427 GSGLNQTFRECAKMERNANRYTIKNLLPYRNIHVKLILSNPEGRKEGKEVTFQTDEDVPG 486
Query 617 EIEA 620
I +
Sbjct 487 GIAS 490
>sp|Q9D2H5|TRI42_MOUSE Tripartite motif-containing protein 42
OS=Mus musculus OX=10090 GN=Trim42 PE=2 SV=2
Length=723
Score = 34.7 bits (78), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 12/27 (44%), Positives = 20/27 (74%), Gaps = 0/27 (0%)
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ +L P TEY+F++R + ++G G WSD
Sbjct 666 LHNLTPNTEYLFKVRAINDNGPGQWSD 692
>sp|O42414|NFASC_CHICK Neurofascin OS=Gallus gallus OX=9031 GN=NFASC
PE=1 SV=1
Length=1369
Score = 34.7 bits (78), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 29/124 (23%), Positives = 52/124 (42%), Gaps = 8/124 (6%)
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+ N ++ + N G + P + P+ P L I L SI L W +P
Sbjct 916 YSNYKLEMVVTNGRGDGPRSEVKEFPTPEGVPSSPRYLR-IRQPNLESI-NLEWDHPEHP 973
Query 251 SVIILKYNIQYRTK------DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ ++ YN++Y+ + S + E+ + ++ FTVQ P + Y F +R +
Sbjct 974 NGVLTGYNLRYQASCLSSPVNGSKTGRTLVENFSPNQTRFTVQRTDPISRYRFFLRARTQ 1033
Query 305 DGKG 308
G G
Sbjct 1034 VGDG 1037
>sp|G4SLH0|TTN1_CAEEL Titin homolog OS=Caenorhabditis elegans
OX=6239 GN=ttn-1 PE=1 SV=2
Length=18562
Score = 34.7 bits (78), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 18/59 (31%), Positives = 28/59 (47%), Gaps = 6/59 (10%)
Query 257 YNIQYRTKDASTWSQIPPEDTASTRS-SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
Y ++ R D W ST+S ++ L P TEY+FR+ + G G WS+ +
Sbjct 17184 YEVERRCPDQREWVSC-----GSTKSLELEIKGLTPNTEYIFRVAGKNKQGLGEWSEMT 17237
Score = 34.7 bits (78), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 30/141 (21%), Positives = 63/141 (45%), Gaps = 21/141 (15%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQI----PPEDTASTRSSFTVQDLKPFTEY 295
+++TW + K ++ QY++ +S W+ + P ++A+T S + L+ Y
Sbjct 14368 VEVTWKSDGEKEFVV-----QYKSDGSSIWASVDIGGPRSESAAT-SKCIIDGLREGIPY 14421
Query 296 VFRIRCMKEDGKGYWSD-------WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
VFR+ + G G +S+ +++A + +P K P H G+ +
Sbjct 14422 VFRVAARNQHGTGEFSEPTIPVVVLADDAPRVLKAIKPVKIPKKGELRLECHAAGHPAPE 14481
Query 349 LVW----KTLPPFEANGKILD 365
+W K + P + N +I++
Sbjct 14482 YIWYKDGKEIIPTDENTEIVN 14502
Score = 34.3 bits (77), Expect = 9.1, Method: Compositional matrix adjust.
Identities = 29/117 (25%), Positives = 54/117 (46%), Gaps = 8/117 (7%)
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS-VI 253
E V+ +N G+V FD P+ P ++SV+ +E S L + WT P+ +
Sbjct 14127 EYEVKLKNEFGEVAQ---KFDVKVNDTPSAPGDVSVVKAE--SDCLHIEWTAPTEDNGAE 14181
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
+ Y I+ + + ++ ++S+ V DL+ T Y+ RI + + G G +
Sbjct 14182 VTSYVIEKKESGRRKFHKVAT--VNGKKTSYVVDDLEIETPYIVRIAAVNKFGTGEF 14236
>sp|Q2Q0I9|FNDC1_RAT Fibronectin type III domain-containing protein
1 OS=Rattus norvegicus OX=10116 GN=Fndc1 PE=1 SV=2
Length=1779
Score = 34.7 bits (78), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 54/195 (28%), Positives = 81/195 (42%), Gaps = 36/195 (18%)
Query 242 LTWTNPSI----KSVIILKYNIQYRTKDAST---WSQIPPEDTASTRSSFTVQDLKPFTE 294
+ W +P + + V +Y ++YR K S + Q+ S R + V L P T
Sbjct 223 VAWVDPLVEKQKRVVASRQYTVRYREKGESARWDYKQV------SNRRAL-VDSLIPDTV 275
Query 295 YVFRIRCMK--EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV-W 351
Y F +R + DGK WS T E P+ AP ++ P G TV V W
Sbjct 276 YEFAVRISQGERDGK-----WSASVFQRTPESAPTTAPEN-LRVWP--VNGKPTVVTVSW 327
Query 352 KTLPPFEANGK----ILDYEVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNL 405
LP E+ GK IL Y L + + ++ + T V+ +RYL + N
Sbjct 328 DALP--ESEGKVKEYILSYAPALKPFGAKSLTFSGHTTSALVDGLQPGERYLFKIRATNR 385
Query 406 VGK---SDAAVLTIP 417
G+ S A ++ IP
Sbjct 386 RGQGPHSKAFIVAIP 400
Score = 34.3 bits (77), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 36/142 (25%), Positives = 59/142 (42%), Gaps = 24/142 (17%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVII---LKYNIQYRTKDASTWSQIPPEDTASTR 281
P N++V+ E S + + W N +I ++ L Y+ Y + WS S+
Sbjct 1544 PRNITVVAMEGCHSFVIVDW-NKAIPGDVVTGYLVYSASYEDFIRNKWST-----QTSSV 1597
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED------RPSKAPSFW-- 333
+ +++LKP T Y F+++ G G S S +T D RP W
Sbjct 1598 THLPIENLKPNTRYYFKVQAKNPHGYG---PVSPSVSFVTESDNPLLVVRPPGGEPIWIP 1654
Query 334 --YKIDPSHT--QGYRTVQLVW 351
+K DP +T G + V+ W
Sbjct 1655 FAFKHDPGYTDCHGRQYVKRTW 1676
>sp|P11799|MYLK_CHICK Myosin light chain kinase, smooth muscle
OS=Gallus gallus OX=9031 GN=Mylk PE=1 SV=2
Length=1906
Score = 34.7 bits (78), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 31/101 (31%), Positives = 45/101 (45%), Gaps = 9/101 (9%)
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS-VIILKYNI 259
EN LG + +N V K P+PP S+ SS L L+W S + Y +
Sbjct 1300 ENKLGSRQA-QVNLTVVDK--PDPPAGTPCA-SDIRSSSLTLSWYGSSYDGGSAVQSYTV 1355
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
+ + W+ + T +SF VQDL+ EY FR+R
Sbjct 1356 EIWNSVDNKWTDL----TTCRSTSFNVQDLQADREYKFRVR 1392
>sp|O02466|ILPR_BRALA Insulin-like peptide receptor OS=Branchiostoma
lanceolatum OX=7740 PE=2 SV=1
Length=1363
Score = 34.3 bits (77), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 24/96 (25%), Positives = 45/96 (47%), Gaps = 8/96 (8%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS-TWSQIPPEDTASTR 281
N P N++V+ +E + KL W P + +++ YNI+Y+ + + Q P+ + +
Sbjct 812 NIPGNITVVEIKE--DMAKLYWPKPDSPNSMVVHYNIEYKKLGSDFNYEQQEPKCVENFK 869
Query 282 ----SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+T+ +L Y R R G G WS++
Sbjct 870 FLQSQGYTISNLVA-GNYSVRFRATSFAGNGSWSNY 904
>sp|B8VIW9|FP_ACRMI Fibronectin type III domain-containing protein
OS=Acropora millepora OX=45264 PE=1 SV=1
Length=1280
Score = 34.3 bits (77), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 35/110 (32%), Positives = 47/110 (43%), Gaps = 18/110 (16%)
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+TV LKP+T Y F I G G SD + + T E P PS Q
Sbjct 900 YTVTGLKPYTNYKFVITAYNSGGNGPESD---QVAADTDEAEPGP---------PSDVQV 947
Query 344 Y---RTVQLVWKTLPPFEANGKILDYEV-TLTRWKSHLQNYTVNATKLTV 389
+ + + + W+ PP E NG I +Y V T T S + TVN + V
Sbjct 948 FVFAKYILVTWQ--PPSEPNGVITNYRVGTETYTGSQPTDVTVNMEETGV 995
>sp|Q02246|CNTN2_HUMAN Contactin-2 OS=Homo sapiens OX=9606 GN=CNTN2
PE=1 SV=1
Length=1040
Score = 34.3 bits (77), Expect = 7.8, Method: Compositional matrix adjust.
Identities = 20/73 (27%), Positives = 32/73 (44%), Gaps = 2/73 (3%)
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP--PEDTASTRSSFTVQDLKPFTEY 295
+ ++L+W+ I KY +Q RT A W Q+ P + + V L P+ +Y
Sbjct 622 TTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNAETAQVLGLTPWMDY 681
Query 296 VFRIRCMKEDGKG 308
FR+ G G
Sbjct 682 EFRVIASNILGTG 694
>sp|Q5ZJP5|FND3A_CHICK Fibronectin type-III domain-containing
protein 3a OS=Gallus gallus OX=9031 GN=FNDC3A PE=2 SV=2
Length=1198
Score = 34.3 bits (77), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 50/208 (24%), Positives = 81/208 (39%), Gaps = 28/208 (13%)
Query 183 TVDYSTVYFVN-------IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
TV YF++ + ++A N+LG H + P+PP V S
Sbjct 907 TVGKVLSYFIDGLQPDTTYRIRIQALNSLGAGPFSHTIKLKTKPLPPDPPRLECVAYS-- 964
Query 236 LSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
S LKL W + K++ ++Y++Q K+ S ++ VQ L T
Sbjct 965 -SQTLKLKWGEGTAKALTDSIQYHLQMEDKNGRFVSLY-----RGPCHTYKVQRLSESTS 1018
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS--KAPSFWYKIDPSHTQGYRTVQLVWK 352
Y F I+ E G+G S+E T + P+ KAP D T ++ W+
Sbjct 1019 YKFCIQACNEAGEG---PLSQEYVFTTPKSVPAALKAPRIERIND-------HTCEITWE 1068
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNY 380
L P + + I +V + + Q Y
Sbjct 1069 VLQPMKGDPVIYCLQVMVGKDSEFKQIY 1096
>sp|Q97Z97|Y1033_SACS2 Kelch domain-containing protein SSO1033
OS=Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617
/ JCM 11322 / P2) OX=273057 GN=SSO1033 PE=3 SV=1
Length=725
Score = 33.9 bits (76), Expect = 8.6, Method: Compositional matrix adjust.
Identities = 50/175 (29%), Positives = 69/175 (39%), Gaps = 35/175 (20%)
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP--- 338
+S+TV LK Y F + G +S +S I P+ P +P
Sbjct 372 TSYTVTGLKDGITYYFEVLAYNSIG------YSSPSSIIALT--PASVP------NPPQL 417
Query 339 -SHTQGYRTVQLVWKTLPP-FEANGKILDYEVTLTRWKSHLQNYTVNATKLTV-NLT-ND 394
S G V L W LPP F +L Y V + S + ++ VN+T LT+ NLT N
Sbjct 418 VSVKYGNDNVTLNW--LPPTFSGGYLLLGYYVIVKNENSMVSSHFVNSTSLTISNLTPNV 475
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP----KDNMLWVEWTT 445
Y + N +G S VLT+ P+ F N + V WTT
Sbjct 476 TYNVFIYAVNKLGNSSPLVLTV--------VPITKASVFAFITKLGNGILVNWTT 522
>sp|P26955|IL3RB_MOUSE Cytokine receptor common subunit beta OS=Mus
musculus OX=10090 GN=Csf2rb PE=1 SV=2
Length=896
Score = 33.9 bits (76), Expect = 8.6, Method: Compositional matrix adjust.
Identities = 48/197 (24%), Positives = 79/197 (40%), Gaps = 17/197 (9%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL---KSEWATHKFADCKAKRDTPTSCTV 184
+P+NL C + + + C W+ +T +F L S A + C P +V
Sbjct 247 QPQNLQCFFDGIQSLHCSWEVWTQTTGSVSFGLFYRPSPVAPEE--KCSPVVKEPPGASV 304
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHI---NFDPVYKVKPNPPHNLSVINSEELSSILK 241
T Y ++ V + ++ V+ H+ F Y P L++ + + S
Sbjct 305 --YTRYHCSLPVPEPSAHSQYTVSVKHLEQGKFIMSYNHIQMEPPTLNLTKNRDSYS--- 359
Query 242 LTW-TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
L W T S I + +QY+ K + +W E+ S + L+P T Y R+R
Sbjct 360 LHWETQKMAYSFIEHTFQVQYK-KKSDSWEDSKTENLDRAH-SMDLSQLEPDTSYCARVR 417
Query 301 CMK-EDGKGYWSDWSEE 316
+ G WS WSEE
Sbjct 418 VKPISNYDGIWSKWSEE 434
>sp|P10039|TENA_CHICK Tenascin OS=Gallus gallus OX=9031 GN=TNC
PE=1 SV=2
Length=1808
Score = 33.9 bits (76), Expect = 9.2, Method: Compositional matrix adjust.
Identities = 49/188 (26%), Positives = 70/188 (37%), Gaps = 12/188 (6%)
Query 436 DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLIT 495
+N V WT PR V Y + + ++ P + DG+ RT L L Y +
Sbjct 1330 ENSATVSWTPPRSRVDSYRVSYVPITGGTPNVV---TVDGSKTRTKLV-KLVPGVDYNVN 1385
Query 496 VTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYT 555
+ V G E I LK A S V + +EA+ W V N Y
Sbjct 1386 IISV--KGFEESEPISGILKTALDSPSGLV-VMNITDSEALATWQPAIAAVDN-----YI 1437
Query 556 IFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ 615
+ Y + E V + EY L+ L T Y +R+ A D + FTT A
Sbjct 1438 VSYSSEDEPEVTQMVSGNTVEYDLNGLRPATEYTLRVHAVKDAQKSETLSTQFTTGLDAP 1497
Query 616 GEIEAIVV 623
++ A V
Sbjct 1498 KDLSATEV 1505
>sp|Q9HBE5|IL21R_HUMAN Interleukin-21 receptor OS=Homo sapiens
OX=9606 GN=IL21R PE=1 SV=1
Length=538
Score = 33.5 bits (75), Expect = 9.6, Method: Compositional matrix adjust.
Identities = 25/108 (23%), Positives = 48/108 (44%), Gaps = 5/108 (5%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTA 278
+KP PP N++V S + + + + +P+ + L+Y +QYR + W+ P
Sbjct 118 IKPAPPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQYELQYRNR-GDPWAVSPRRKLI 176
Query 279 STRS---SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
S S S + + + Y ++R G Y WSE + + ++
Sbjct 177 SVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQ 224
Lambda K H a alpha
0.315 0.131 0.398 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 106093335362
Results from round 2
Query= sp|P40189|IL6RB_HUMAN Interleukin-6 receptor subunit beta OS=Homo
sapiens OX=9606 GN=IL6ST PE=1 SV=2
Length=918
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|P40189|IL6RB_HUMAN Interleukin-6 receptor subunit beta OS=Homo... 1301 0.0
sp|Q00560|IL6RB_MOUSE Interleukin-6 receptor subunit beta OS=Mus ... 1199 0.0
sp|P40190|IL6RB_RAT Interleukin-6 receptor subunit beta OS=Rattus... 1184 0.0
sp|Q99062|CSF3R_HUMAN Granulocyte colony-stimulating factor recep... 593 0.0
sp|P40223|CSF3R_MOUSE Granulocyte colony-stimulating factor recep... 575 0.0
sp|Q5XNR9|LIFR_CANLF Leukemia inhibitory factor receptor OS=Canis... 504 2e-161
sp|Q9BEG2|I12R2_BOVIN Interleukin-12 receptor subunit beta-2 OS=B... 495 2e-160
sp|Q8MJS1|I12R2_PIG Interleukin-12 receptor subunit beta-2 OS=Sus... 494 3e-160
sp|P42702|LIFR_HUMAN Leukemia inhibitory factor receptor OS=Homo ... 497 1e-158
sp|P97378|I12R2_MOUSE Interleukin-12 receptor subunit beta-2 OS=M... 480 1e-154
sp|Q99665|I12R2_HUMAN Interleukin-12 receptor subunit beta-2 OS=H... 471 2e-151
sp|O70535|LIFR_RAT Leukemia inhibitory factor receptor OS=Rattus ... 475 3e-150
sp|P42703|LIFR_MOUSE Leukemia inhibitory factor receptor OS=Mus m... 472 4e-149
sp|Q8NI17|IL31R_HUMAN Interleukin-31 receptor subunit alpha OS=Ho... 445 7e-143
sp|Q8K5B1|IL31R_MOUSE Interleukin-31 receptor subunit alpha OS=Mu... 441 2e-141
sp|Q65Z14|OSMR_RAT Oncostatin-M-specific receptor subunit beta OS... 415 6e-129
sp|Q99650|OSMR_HUMAN Oncostatin-M-specific receptor subunit beta ... 410 8e-127
sp|O70458|OSMR_MOUSE Oncostatin-M-specific receptor subunit beta ... 409 1e-126
sp|Q62959|LEPR_RAT Leptin receptor OS=Rattus norvegicus OX=10116 ... 368 7e-110
sp|P48357|LEPR_HUMAN Leptin receptor OS=Homo sapiens OX=9606 GN=L... 366 4e-109
sp|P48356|LEPR_MOUSE Leptin receptor OS=Mus musculus OX=10090 GN=... 366 6e-109
sp|Q9MYL0|LEPR_MACMU Leptin receptor OS=Macaca mulatta OX=9544 GN... 361 3e-107
sp|O02671|LEPR_PIG Leptin receptor OS=Sus scrofa OX=9823 GN=LEPR ... 361 5e-107
sp|Q6UWB1|I27RA_HUMAN Interleukin-27 receptor subunit alpha OS=Ho... 309 2e-92
sp|O70394|I27RA_MOUSE Interleukin-27 receptor subunit alpha OS=Mu... 308 3e-92
sp|Q6V4S5|SDK2_MOUSE Protein sidekick-2 OS=Mus musculus OX=10090 ... 312 3e-88
sp|Q58EX2|SDK2_HUMAN Protein sidekick-2 OS=Homo sapiens OX=9606 G... 302 1e-84
sp|Q8AV58|SDK1_CHICK Protein sidekick-1 OS=Gallus gallus OX=9031 ... 299 1e-83
sp|Q07409|CNTN3_MOUSE Contactin-3 OS=Mus musculus OX=10090 GN=Cnt... 289 8e-82
sp|Q3UH53|SDK1_MOUSE Protein sidekick-1 OS=Mus musculus OX=10090 ... 293 1e-81
sp|Q8AV57|SDK2_CHICK Protein sidekick-2 OS=Gallus gallus OX=9031 ... 291 6e-81
sp|Q7Z5N4|SDK1_HUMAN Protein sidekick-1 OS=Homo sapiens OX=9606 G... 290 8e-81
sp|Q8IWV2|CNTN4_HUMAN Contactin-4 OS=Homo sapiens OX=9606 GN=CNTN... 285 1e-80
sp|Q62845|CNTN4_RAT Contactin-4 OS=Rattus norvegicus OX=10116 GN=... 285 1e-80
sp|Q62682|CNTN3_RAT Contactin-3 OS=Rattus norvegicus OX=10116 GN=... 285 2e-80
sp|Q69Z26|CNTN4_MOUSE Contactin-4 OS=Mus musculus OX=10090 GN=Cnt... 284 2e-80
sp|Q9UQ52|CNTN6_HUMAN Contactin-6 OS=Homo sapiens OX=9606 GN=CNTN... 277 1e-77
sp|A7MBJ4|PTPRF_BOVIN Receptor-type tyrosine-protein phosphatase ... 274 2e-75
sp|Q64604|PTPRF_RAT Receptor-type tyrosine-protein phosphatase F ... 272 6e-75
sp|A2A8L5|PTPRF_MOUSE Receptor-type tyrosine-protein phosphatase ... 272 7e-75
sp|P10586|PTPRF_HUMAN Receptor-type tyrosine-protein phosphatase ... 272 7e-75
sp|P97527|CNTN5_RAT Contactin-5 OS=Rattus norvegicus OX=10116 GN=... 268 2e-74
sp|O94779|CNTN5_HUMAN Contactin-5 OS=Homo sapiens OX=9606 GN=CNTN... 268 3e-74
sp|Q9JM58|CRLF1_MOUSE Cytokine receptor-like factor 1 OS=Mus musc... 252 6e-74
sp|P97528|CNTN6_RAT Contactin-6 OS=Rattus norvegicus OX=10116 GN=... 265 9e-74
sp|P68500|CNTN5_MOUSE Contactin-5 OS=Mus musculus OX=10090 GN=Cnt... 266 1e-73
sp|O75462|CRLF1_HUMAN Cytokine receptor-like factor 1 OS=Homo sap... 250 3e-73
sp|Q5VTT5|MYOM3_HUMAN Myomesin-3 OS=Homo sapiens OX=9606 GN=MYOM3... 264 4e-72
sp|Q810U4|NRCAM_MOUSE Neuronal cell adhesion molecule OS=Mus musc... 261 1e-71
sp|Q92823|NRCAM_HUMAN Neuronal cell adhesion molecule OS=Homo sap... 260 4e-71
sp|P97686|NRCAM_RAT Neuronal cell adhesion molecule OS=Rattus nor... 260 4e-71
sp|P23468|PTPRD_HUMAN Receptor-type tyrosine-protein phosphatase ... 260 6e-71
sp|A4IFW2|PTPRF_DANRE Receptor-type tyrosine-protein phosphatase ... 259 1e-70
sp|Q90610|NEO1_CHICK Neogenin (Fragment) OS=Gallus gallus OX=9031... 257 7e-70
sp|Q64487|PTPRD_MOUSE Receptor-type tyrosine-protein phosphatase ... 257 7e-70
sp|P97798|NEO1_MOUSE Neogenin OS=Mus musculus OX=10090 GN=Neo1 PE... 252 2e-68
sp|A2ABU4|MYOM3_MOUSE Myomesin-3 OS=Mus musculus OX=10090 GN=Myom... 252 4e-68
sp|Q8K4B4|IL23R_MOUSE Interleukin-23 receptor OS=Mus musculus OX=... 241 1e-67
sp|Q8WZ42|TITIN_HUMAN Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=4 250 4e-67
sp|Q13332|PTPRS_HUMAN Receptor-type tyrosine-protein phosphatase ... 249 6e-67
sp|P14781|CNTN1_CHICK Contactin-1 OS=Gallus gallus OX=9031 GN=CNT... 245 1e-66
sp|F1NY98|DSCAM_CHICK Cell adhesion molecule DSCAM OS=Gallus gall... 248 1e-66
sp|P97603|NEO1_RAT Neogenin (Fragment) OS=Rattus norvegicus OX=10... 247 1e-66
sp|Q92859|NEO1_HUMAN Neogenin OS=Homo sapiens OX=9606 GN=NEO1 PE=... 244 1e-65
sp|Q9N3X8|SDK_CAEEL Protein sidekick homolog OS=Caenorhabditis el... 243 3e-65
sp|Q60ZN5|SDK_CAEBR Protein sidekick homolog OS=Caenorhabditis br... 242 1e-64
sp|A2ASS6|TITIN_MOUSE Titin OS=Mus musculus OX=10090 GN=Ttn PE=1 ... 241 2e-64
sp|P0C5E4|PTPRQ_MOUSE Phosphatidylinositol phosphatase PTPRQ OS=M... 240 2e-64
sp|Q9ERC8|DSCAM_MOUSE Cell adhesion molecule DSCAM OS=Mus musculu... 239 7e-64
sp|Q8VHZ8|DSCAM_RAT Cell adhesion molecule DSCAM OS=Rattus norveg... 239 7e-64
sp|O60469|DSCAM_HUMAN Cell adhesion molecule DSCAM OS=Homo sapien... 239 7e-64
sp|Q5VWK5|IL23R_HUMAN Interleukin-23 receptor OS=Homo sapiens OX=... 226 3e-62
sp|Q64605|PTPRS_RAT Receptor-type tyrosine-protein phosphatase S ... 232 9e-62
sp|P52179|MYOM1_HUMAN Myomesin-1 OS=Homo sapiens OX=9606 GN=MYOM1... 231 2e-61
sp|B0V2N1|PTPRS_MOUSE Receptor-type tyrosine-protein phosphatase ... 227 5e-60
sp|Q8K3K1|USH2A_RAT Usherin OS=Rattus norvegicus OX=10116 GN=Ush2... 216 2e-56
sp|G5EF96|UNC40_CAEEL Netrin receptor unc-40 OS=Caenorhabditis el... 210 2e-54
sp|Q2QI47|USH2A_MOUSE Usherin OS=Mus musculus OX=10090 GN=Ush2A P... 209 6e-54
sp|P32004|L1CAM_HUMAN Neural cell adhesion molecule L1 OS=Homo sa... 205 6e-53
sp|Q90374|PRLR_COLLI Prolactin receptor OS=Columba livia OX=8932 ... 201 1e-52
sp|P43146|DCC_HUMAN Netrin receptor DCC OS=Homo sapiens OX=9606 G... 204 1e-52
sp|Q63155|DCC_RAT Netrin receptor DCC OS=Rattus norvegicus OX=101... 202 6e-52
sp|Q28172|PRLR_BOVIN Prolactin receptor OS=Bos taurus OX=9913 GN=... 194 2e-51
sp|P13944|COCA1_CHICK Collagen alpha-1(XII) chain OS=Gallus gallu... 201 2e-51
sp|P70211|DCC_MOUSE Netrin receptor DCC OS=Mus musculus OX=10090 ... 200 2e-51
sp|P14787|PRLR_RABIT Prolactin receptor OS=Oryctolagus cuniculus ... 193 7e-51
sp|O46561|PRLR_SHEEP Prolactin receptor OS=Ovis aries OX=9940 GN=... 191 1e-50
sp|Q9VN14|CONT_DROME Contactin OS=Drosophila melanogaster OX=7227... 197 2e-50
sp|O75445|USH2A_HUMAN Usherin OS=Homo sapiens OX=9606 GN=USH2A PE... 196 6e-50
sp|Q28235|PRLR_CEREL Prolactin receptor OS=Cervus elaphus OX=9860... 188 1e-49
sp|Q6JTA8|PRLR_PIG Prolactin receptor OS=Sus scrofa OX=9823 GN=PR... 189 2e-49
sp|P05710|PRLR_RAT Prolactin receptor OS=Rattus norvegicus OX=101... 188 3e-49
sp|Q91094|PRLR_MELGA Prolactin receptor OS=Meleagris gallopavo OX... 190 5e-49
sp|Q04594|PRLR_CHICK Prolactin receptor OS=Gallus gallus OX=9031 ... 190 9e-49
sp|F1NWE3|PTPRS_CHICK Receptor-type tyrosine-protein phosphatase ... 187 3e-47
sp|Q08501|PRLR_MOUSE Prolactin receptor OS=Mus musculus OX=10090 ... 181 6e-47
sp|P16471|PRLR_HUMAN Prolactin receptor OS=Homo sapiens OX=9606 G... 180 2e-46
sp|Q2EY13|PRTGB_DANRE Protogenin B (Fragment) OS=Danio rerio OX=7... 184 2e-46
sp|P51641|CNTFR_CHICK Ciliary neurotrophic factor receptor subuni... 164 3e-43
sp|Q9EQS9|IGDC4_MOUSE Immunoglobulin superfamily DCC subclass mem... 168 2e-41
sp|Q8TDY8|IGDC4_HUMAN Immunoglobulin superfamily DCC subclass mem... 167 6e-41
sp|P26992|CNTFR_HUMAN Ciliary neurotrophic factor receptor subuni... 158 7e-41
sp|Q91513|PRLR_ORENI Prolactin receptor OS=Oreochromis niloticus ... 163 1e-40
sp|Q71DR4|CNTFR_CANLF Ciliary neurotrophic factor receptor subuni... 157 1e-40
sp|P22273|IL6RA_RAT Interleukin-6 receptor subunit alpha OS=Rattu... 159 2e-40
sp|P22272|IL6RA_MOUSE Interleukin-6 receptor subunit alpha OS=Mus... 158 5e-40
sp|O88507|CNTFR_MOUSE Ciliary neurotrophic factor receptor subuni... 154 1e-39
sp|Q08406|CNTFR_RAT Ciliary neurotrophic factor receptor subunit ... 153 3e-39
sp|Q5RF19|I11RA_PONAB Interleukin-11 receptor subunit alpha OS=Po... 153 1e-38
sp|Q99MF4|I11RA_RAT Interleukin-11 receptor subunit alpha OS=Ratt... 152 2e-38
sp|Q14626|I11RA_HUMAN Interleukin-11 receptor subunit alpha OS=Ho... 152 2e-38
sp|Q64385|I11RA_MOUSE Interleukin-11 receptor subunit alpha-1 OS=... 150 1e-37
sp|P70225|I11RB_MOUSE Interleukin-11 receptor subunit alpha-2 OS=... 148 4e-37
sp|H2A0L7|FND1_PINMG Fibronectin type III domain-containing prote... 146 6e-35
sp|Q0E9H9|DSCA1_DROME Cell adhesion molecule Dscam1 OS=Drosophila... 147 2e-34
sp|O18796|IL6RA_PIG Interleukin-6 receptor subunit alpha OS=Sus s... 139 1e-33
sp|O09127|EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus musculus OX... 143 1e-33
sp|P29322|EPHA8_HUMAN Ephrin type-A receptor 8 OS=Homo sapiens OX... 142 3e-33
sp|Q61772|EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus musculus OX... 141 4e-33
sp|O42422|EPHA7_CHICK Ephrin type-A receptor 7 OS=Gallus gallus O... 141 5e-33
sp|P08887|IL6RA_HUMAN Interleukin-6 receptor subunit alpha OS=Hom... 136 6e-33
sp|Q15375|EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo sapiens OX... 140 1e-32
sp|P54759|EPHA7_RAT Ephrin type-A receptor 7 OS=Rattus norvegicus... 139 2e-32
sp|Q7TPD3|ROBO2_MOUSE Roundabout homolog 2 OS=Mus musculus OX=100... 140 2e-32
sp|Q9UF33|EPHA6_HUMAN Ephrin type-A receptor 6 OS=Homo sapiens OX... 136 2e-31
sp|P78552|I13R1_HUMAN Interleukin-13 receptor subunit alpha-1 OS=... 132 2e-31
sp|Q62413|EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus musculus OX... 133 3e-30
sp|P54758|EPHA6_RAT Ephrin type-A receptor 6 OS=Rattus norvegicus... 130 2e-29
sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 OS=Homo sapiens OX... 129 4e-29
sp|P34902|IL2RG_MOUSE Cytokine receptor common subunit gamma OS=M... 96.5 5e-20
Sequences not found previously or not previously below threshold:
sp|Q9P232|CNTN3_HUMAN Contactin-3 OS=Homo sapiens OX=9606 GN=CNTN... 284 2e-80
sp|Q9JMB8|CNTN6_MOUSE Contactin-6 OS=Mus musculus OX=10090 GN=Cnt... 265 1e-73
sp|Q90W79|CNTN5_CHICK Contactin-5 OS=Gallus gallus OX=9031 GN=CNT... 253 2e-69
sp|O88488|PTPRQ_RAT Phosphatidylinositol phosphatase PTPRQ OS=Rat... 254 8e-69
sp|Q7ZW34|CNTN5_DANRE Contactin-5 OS=Danio rerio OX=7955 GN=cntn5... 242 2e-65
sp|Q02173|MPSF_CHICK M-protein, striated muscle OS=Gallus gallus ... 235 7e-63
sp|Q12860|CNTN1_HUMAN Contactin-1 OS=Homo sapiens OX=9606 GN=CNTN... 231 6e-62
sp|P12960|CNTN1_MOUSE Contactin-1 OS=Mus musculus OX=10090 GN=Cnt... 228 6e-61
sp|Q63198|CNTN1_RAT Contactin-1 OS=Rattus norvegicus OX=10116 GN=... 228 8e-61
sp|Q28106|CNTN1_BOVIN Contactin-1 OS=Bos taurus OX=9913 GN=CNTN1 ... 225 4e-60
sp|P16621|LAR_DROME Tyrosine-protein phosphatase Lar OS=Drosophil... 227 9e-60
sp|Q4VA61|DSCL1_MOUSE Cell adhesion molecule DSCAML1 OS=Mus muscu... 225 2e-59
sp|Q8TD84|DSCL1_HUMAN Cell adhesion molecule DSCAML1 OS=Homo sapi... 222 2e-58
sp|P35331|NRCAM_CHICK Neuronal cell adhesion molecule OS=Gallus g... 221 4e-58
sp|E1C8P7|DSCL1_CHICK Cell adhesion molecule DSCAML1 OS=Gallus ga... 219 2e-57
sp|Q9UMZ3|PTPRQ_HUMAN Phosphatidylinositol phosphatase PTPRQ OS=H... 218 6e-57
sp|P11627|L1CAM_MOUSE Neural cell adhesion molecule L1 OS=Mus mus... 212 2e-55
sp|Q05695|L1CAM_RAT Neural cell adhesion molecule L1 OS=Rattus no... 212 3e-55
sp|P70232|NCHL1_MOUSE Neural cell adhesion molecule L1-like prote... 208 3e-54
sp|P54296|MYOM2_HUMAN Myomesin-2 OS=Homo sapiens OX=9606 GN=MYOM2... 206 2e-53
sp|Q90478|L1CA1_DANRE Neural cell adhesion molecule L1.1 (Fragmen... 204 1e-52
sp|O00533|NCHL1_HUMAN Neural cell adhesion molecule L1-like prote... 203 2e-52
sp|Q9VS29|DSCL_DROME Cell adhesion molecule Dscam2 OS=Drosophila ... 203 3e-52
sp|Q98902|L1CAM_TAKRU Neural cell adhesion molecule L1 OS=Takifug... 195 8e-50
sp|Q9BMN8|LAR_CAEEL Tyrosine-protein phosphatase Lar-like OS=Caen... 194 2e-49
sp|Q8AXZ4|CNT1A_DANRE Contactin-1a OS=Danio rerio OX=7955 GN=cntn... 193 3e-49
sp|O97394|SDK_DROME Protein sidekick OS=Drosophila melanogaster O... 192 9e-49
sp|Q62234|MYOM1_MOUSE Myomesin-1 OS=Mus musculus OX=10090 GN=Myom... 190 3e-48
sp|O94856|NFASC_HUMAN Neurofascin OS=Homo sapiens OX=9606 GN=NFAS... 188 9e-48
sp|Q61330|CNTN2_MOUSE Contactin-2 OS=Mus musculus OX=10090 GN=Cnt... 186 4e-47
sp|Q02246|CNTN2_HUMAN Contactin-2 OS=Homo sapiens OX=9606 GN=CNTN... 186 5e-47
sp|B8VIW9|FP_ACRMI Fibronectin type III domain-containing protein... 186 7e-47
sp|P28685|CNTN2_CHICK Contactin-2 OS=Gallus gallus OX=9031 GN=CNT... 184 1e-46
sp|P22063|CNTN2_RAT Contactin-2 OS=Rattus norvegicus OX=10116 GN=... 183 2e-46
sp|O42414|NFASC_CHICK Neurofascin OS=Gallus gallus OX=9031 GN=NFA... 180 3e-45
sp|Q60847|COCA1_MOUSE Collagen alpha-1(XII) chain OS=Mus musculus... 178 4e-44
sp|Q2EY14|PRTGA_DANRE Protogenin A OS=Danio rerio OX=7955 GN=prtg... 173 5e-43
sp|Q23551|UNC22_CAEEL Twitchin OS=Caenorhabditis elegans OX=6239 ... 173 1e-42
sp|Q99715|COCA1_HUMAN Collagen alpha-1(XII) chain OS=Homo sapiens... 173 1e-42
sp|Q2VWP7|PRTG_HUMAN Protogenin OS=Homo sapiens OX=9606 GN=PRTG P... 170 5e-42
sp|Q91145|COCA1_NOTVI Collagen alpha-1(XII) chain (Fragment) OS=N... 167 4e-41
sp|Q2EY15|PRTG_MOUSE Protogenin OS=Mus musculus OX=10090 GN=Prtg ... 167 5e-41
sp|Q2VWP9|PRTG_RAT Protogenin OS=Rattus norvegicus OX=10116 GN=Pr... 165 2e-40
sp|Q589G5|PRTG_CHICK Protogenin OS=Gallus gallus OX=9031 GN=PRTG ... 164 4e-40
sp|Q3KNY0|IGFN1_MOUSE Immunoglobulin-like and fibronectin type II... 164 7e-40
sp|Q28902|COCA1_RABIT Collagen alpha-1(XII) chain (Fragment) OS=O... 160 8e-40
sp|Q8BX90|FND3A_MOUSE Fibronectin type-III domain-containing prot... 159 2e-38
sp|Q53EP0|FND3B_HUMAN Fibronectin type III domain-containing prot... 157 6e-38
sp|Q02388|CO7A1_HUMAN Collagen alpha-1(VII) chain OS=Homo sapiens... 156 2e-37
sp|Q9Y2H6|FND3A_HUMAN Fibronectin type-III domain-containing prot... 154 6e-37
sp|Q5RBN1|FND3A_PONAB Fibronectin type-III domain-containing prot... 154 6e-37
sp|Q00546|TENR_CHICK Tenascin-R OS=Gallus gallus OX=9031 GN=TNR P... 152 3e-36
sp|Q9I7U4|TITIN_DROME Titin OS=Drosophila melanogaster OX=7227 GN... 151 1e-35
sp|Q9HCK4|ROBO2_HUMAN Roundabout homolog 2 OS=Homo sapiens OX=960... 148 6e-35
sp|Q5ZJP5|FND3A_CHICK Fibronectin type-III domain-containing prot... 147 9e-35
sp|P11276|FINC_MOUSE Fibronectin OS=Mus musculus OX=10090 GN=Fn1 ... 147 1e-34
sp|P04937|FINC_RAT Fibronectin OS=Rattus norvegicus OX=10116 GN=F... 146 4e-34
sp|Q6NWW9|FND3B_MOUSE Fibronectin type III domain-containing prot... 145 4e-34
sp|Q63870|CO7A1_MOUSE Collagen alpha-1(VII) chain OS=Mus musculus... 144 1e-33
sp|Q9UQP3|TENN_HUMAN Tenascin-N OS=Homo sapiens OX=9606 GN=TNN PE... 143 2e-33
sp|Q86VF2|IGFN1_HUMAN Immunoglobulin-like and fibronectin type II... 143 2e-33
sp|Q9P218|COKA1_HUMAN Collagen alpha-1(XX) chain OS=Homo sapiens ... 142 3e-33
sp|Q28749|FINC_RABIT Fibronectin (Fragment) OS=Oryctolagus cunicu... 143 4e-33
sp|Q80Z71|TENN_MOUSE Tenascin-N OS=Mus musculus OX=10090 GN=Tnn P... 142 4e-33
sp|Q91740|FINC_XENLA Fibronectin OS=Xenopus laevis OX=8355 GN=fn1... 142 6e-33
sp|Q28377|FINC_HORSE Fibronectin OS=Equus caballus OX=9796 GN=FN1... 141 8e-33
sp|P11722|FINC_CHICK Fibronectin OS=Gallus gallus OX=9031 GN=FN1 ... 141 1e-32
sp|Q95209|SORL_RABIT Sortilin-related receptor OS=Oryctolagus cun... 140 2e-32
sp|P02751|FINC_HUMAN Fibronectin OS=Homo sapiens OX=9606 GN=FN1 P... 140 2e-32
sp|P07589|FINC_BOVIN Fibronectin OS=Bos taurus OX=9913 GN=FN1 PE=... 140 2e-32
sp|P97685|NFASC_RAT Neurofascin OS=Rattus norvegicus OX=10116 GN=... 137 1e-31
sp|P20241|NRG_DROME Neuroglian OS=Drosophila melanogaster OX=7227... 137 1e-31
sp|Q28275|FINC_CANLF Fibronectin (Fragment) OS=Canis lupus famili... 137 2e-31
sp|Q810U3|NFASC_MOUSE Neurofascin OS=Mus musculus OX=10090 GN=Nfa... 136 3e-31
sp|P35992|PTP10_DROME Tyrosine-protein phosphatase 10D OS=Drosoph... 136 4e-31
sp|Q09165|DIG1_CAEEL Mesocentin OS=Caenorhabditis elegans OX=6239... 135 7e-31
sp|Q92673|SORL_HUMAN Sortilin-related receptor OS=Homo sapiens OX... 135 8e-31
sp|Q91289|FINC_PLEWA Fibronectin (Fragment) OS=Pleurodeles waltl ... 134 8e-31
sp|P28192|PTP4_CAEEL Tyrosine-protein phosphatase 4 OS=Caenorhabd... 134 1e-30
sp|Q92752|TENR_HUMAN Tenascin-R OS=Homo sapiens OX=9606 GN=TNR PE... 133 3e-30
sp|Q6DFV6|FN3C1_MOUSE Fibronectin type III domain containing prot... 131 1e-29
sp|Q9W6V5|PTPRJ_CHICK Receptor-type tyrosine-protein phosphatase ... 130 2e-29
sp|O89026|ROBO1_MOUSE Roundabout homolog 1 OS=Mus musculus OX=100... 129 3e-29
sp|Q9VWE0|DOME_DROME Cytokine receptor OS=Drosophila melanogaster... 128 6e-29
sp|Q80X19|COEA1_MOUSE Collagen alpha-1(XIV) chain OS=Mus musculus... 128 1e-28
sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 OS=Rattus norvegicus... 127 1e-28
sp|P54755|EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallus gallus O... 126 2e-28
sp|Q9Y6N7|ROBO1_HUMAN Roundabout homolog 1 OS=Homo sapiens OX=960... 127 2e-28
sp|P0DSP1|SORL_RAT Sortilin-related receptor OS=Rattus norvegicus... 127 2e-28
sp|O09030|I13R1_MOUSE Interleukin-13 receptor subunit alpha-1 OS=... 122 3e-28
sp|Q03696|NGCA_CHICK Neuronal-glial cell adhesion molecule OS=Gal... 126 4e-28
sp|O08680|EPHA3_RAT Ephrin type-A receptor 3 OS=Rattus norvegicus... 125 5e-28
sp|Q05707|COEA1_HUMAN Collagen alpha-1(XIV) chain OS=Homo sapiens... 126 5e-28
sp|P10039|TENA_CHICK Tenascin OS=Gallus gallus OX=9031 GN=TNC PE=... 125 6e-28
sp|O88307|SORL_MOUSE Sortilin-related receptor OS=Mus musculus OX... 126 7e-28
sp|Q8BYI9|TENR_MOUSE Tenascin-R OS=Mus musculus OX=10090 GN=Tnr P... 124 1e-27
sp|P29320|EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo sapiens OX... 124 1e-27
sp|Q4ZHG4|FNDC1_HUMAN Fibronectin type III domain-containing prot... 124 2e-27
sp|P42701|I12R1_HUMAN Interleukin-12 receptor subunit beta-1 OS=H... 123 2e-27
sp|O55005|ROBO1_RAT Roundabout homolog 1 OS=Rattus norvegicus OX=... 124 2e-27
sp|Q05546|TENR_RAT Tenascin-R OS=Rattus norvegicus OX=10116 GN=Tn... 123 2e-27
sp|Q923P0|COKA1_MOUSE Collagen alpha-1(XX) chain OS=Mus musculus ... 123 3e-27
sp|G5EBF1|SAX3_CAEEL Protein sax-3 OS=Caenorhabditis elegans OX=6... 123 3e-27
sp|P29318|EPHA3_CHICK Ephrin type-A receptor 3 OS=Gallus gallus O... 122 4e-27
sp|P29319|EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus musculus OX... 122 4e-27
sp|Q60805|MERTK_MOUSE Tyrosine-protein kinase Mer OS=Mus musculus... 122 6e-27
sp|H2A0L8|FND2_PINMG Fibronectin type III domain-containing prote... 119 2e-26
sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 OS=Rattus norvegicus... 120 2e-26
sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens OX... 120 2e-26
sp|Q8CBF3|EPHB1_MOUSE Ephrin type-B receptor 1 OS=Mus musculus OX... 120 2e-26
sp|E9Q0N2|PTPRH_MOUSE Receptor-type tyrosine-protein phosphatase ... 119 4e-26
sp|Q5XKE0|MYPC2_MOUSE Myosin-binding protein C, fast-type OS=Mus ... 119 5e-26
sp|Q90688|MYPC3_CHICK Myosin-binding protein C, cardiac-type OS=G... 119 6e-26
sp|P28828|PTPRM_MOUSE Receptor-type tyrosine-protein phosphatase ... 119 7e-26
sp|Q14896|MYPC3_HUMAN Myosin-binding protein C, cardiac-type OS=H... 118 8e-26
sp|Q14324|MYPC2_HUMAN Myosin-binding protein C, fast-type OS=Homo... 118 8e-26
sp|Q96MS0|ROBO3_HUMAN Roundabout homolog 3 OS=Homo sapiens OX=960... 118 1e-25
sp|P57097|MERTK_RAT Tyrosine-protein kinase Mer OS=Rattus norvegi... 117 2e-25
sp|P32018|COEA1_CHICK Collagen alpha-1(XIV) chain OS=Gallus gallu... 118 2e-25
sp|Q91736|EPB1B_XENLA Ephrin type-B receptor 1-B (Fragment) OS=Xe... 117 2e-25
sp|Q91845|EPA4A_XENLA Ephrin type-A receptor 4-A OS=Xenopus laevi... 117 2e-25
sp|P28827|PTPRM_HUMAN Receptor-type tyrosine-protein phosphatase ... 117 2e-25
sp|Q6YI48|PTPRU_CHICK Receptor-type tyrosine-protein phosphatase ... 117 3e-25
sp|Q91694|EPA4B_XENLA Ephrin type-A receptor 4-B OS=Xenopus laevi... 115 6e-25
sp|P56741|MYPC_RAT Myosin-binding protein C, cardiac-type OS=Ratt... 115 1e-24
sp|Q9WTL4|INSRR_MOUSE Insulin receptor-related protein OS=Mus mus... 114 1e-24
sp|Q9U308|JAC1_CAEEL Juxtamembrane domain-associated catenin OS=C... 114 1e-24
sp|P14616|INSRR_HUMAN Insulin receptor-related protein OS=Homo sa... 114 1e-24
sp|Q64716|INSRR_RAT Insulin receptor-related protein OS=Rattus no... 114 2e-24
sp|A0JM20|TYRO3_XENTR Tyrosine-protein kinase receptor TYRO3 OS=X... 113 2e-24
sp|Q92729|PTPRU_HUMAN Receptor-type tyrosine-protein phosphatase ... 114 2e-24
sp|G4SLH0|TTN1_CAEEL Titin homolog OS=Caenorhabditis elegans OX=6... 114 2e-24
sp|Q8BQC3|IGDC3_MOUSE Immunoglobulin superfamily DCC subclass mem... 113 3e-24
sp|Q29116|TENA_PIG Tenascin OS=Sus scrofa OX=9823 GN=TNC PE=1 SV=1 113 3e-24
sp|Q8IVU1|IGDC3_HUMAN Immunoglobulin superfamily DCC subclass mem... 113 4e-24
sp|Q18245|YC27B_CAEEL Ig-like and fibronectin type-III domain-con... 113 4e-24
sp|Q07496|EPHA4_CHICK Ephrin type-A receptor 4 OS=Gallus gallus O... 112 5e-24
sp|H2KZ60|RIG6_CAEEL Contactin rig-6 OS=Caenorhabditis elegans OX... 112 7e-24
sp|B1AUH1|PTPRU_MOUSE Receptor-type tyrosine-protein phosphatase ... 112 8e-24
sp|Q90344|EPHB2_COTJA Ephrin type-B receptor 2 OS=Coturnix japoni... 111 1e-23
sp|O70468|MYPC3_MOUSE Myosin-binding protein C, cardiac-type OS=M... 111 1e-23
sp|P28693|EPHB2_CHICK Ephrin type-B receptor 2 OS=Gallus gallus O... 111 1e-23
sp|Q03137|EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus musculus OX... 111 1e-23
sp|Q8QFP9|TYRO3_XENLA Tyrosine-protein kinase receptor TYRO3 OS=X... 110 2e-23
sp|Q07498|EPHB3_CHICK Ephrin type-B receptor 3 (Fragment) OS=Gall... 110 3e-23
sp|Q80YX1|TENA_MOUSE Tenascin OS=Mus musculus OX=10090 GN=Tnc PE=... 110 3e-23
sp|P55146|TYRO3_RAT Tyrosine-protein kinase receptor TYRO3 OS=Rat... 109 4e-23
sp|Q07494|EPHB1_CHICK Ephrin type-B receptor 1 (Fragment) OS=Gall... 109 4e-23
sp|P54764|EPHA4_HUMAN Ephrin type-A receptor 4 OS=Homo sapiens OX... 109 5e-23
sp|P54763|EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus musculus OX... 109 5e-23
sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens OX... 109 5e-23
sp|O13146|EPHA3_DANRE Ephrin type-A receptor 3 OS=Danio rerio OX=... 108 9e-23
sp|Q91735|EPHB3_XENLA Ephrin type-B receptor 3 OS=Xenopus laevis ... 108 1e-22
sp|P24821|TENA_HUMAN Tenascin OS=Homo sapiens OX=9606 GN=TNC PE=1... 108 1e-22
sp|Q98949|TYRO3_CHICK Tyrosine-protein kinase receptor TYRO3 OS=G... 107 2e-22
sp|P15127|INSR_RAT Insulin receptor OS=Rattus norvegicus OX=10116... 108 2e-22
sp|Q06418|TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3 OS=H... 107 2e-22
sp|P15208|INSR_MOUSE Insulin receptor OS=Mus musculus OX=10090 GN... 107 3e-22
sp|P14617|INSRR_CAVPO Insulin receptor-related protein OS=Cavia p... 107 3e-22
sp|Q00872|MYPC1_HUMAN Myosin-binding protein C, slow-type OS=Homo... 106 4e-22
sp|P35822|PTPRK_MOUSE Receptor-type tyrosine-protein phosphatase ... 106 7e-22
sp|P55144|TYRO3_MOUSE Tyrosine-protein kinase receptor TYRO3 OS=M... 105 7e-22
sp|Q9Z2I4|ROBO3_MOUSE Roundabout homolog 3 OS=Mus musculus OX=100... 105 9e-22
sp|Q9PVZ4|INSR_XENLA Insulin receptor OS=Xenopus laevis OX=8355 G... 105 1e-21
sp|Q60751|IGF1R_MOUSE Insulin-like growth factor 1 receptor OS=Mu... 105 1e-21
sp|Q15262|PTPRK_HUMAN Receptor-type tyrosine-protein phosphatase ... 105 1e-21
sp|P22105|TENX_HUMAN Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB P... 105 1e-21
sp|Q00993|UFO_MOUSE Tyrosine-protein kinase receptor UFO OS=Mus m... 104 1e-21
sp|Q12866|MERTK_HUMAN Tyrosine-protein kinase Mer OS=Homo sapiens... 104 1e-21
sp|P24062|IGF1R_RAT Insulin-like growth factor 1 receptor OS=Ratt... 104 2e-21
sp|P16419|MYPC2_CHICK Myosin-binding protein C, fast-type OS=Gall... 104 2e-21
sp|Q9TU69|GHR_CANLF Growth hormone receptor OS=Canis lupus famili... 103 2e-21
sp|O14522|PTPRT_HUMAN Receptor-type tyrosine-protein phosphatase ... 104 2e-21
sp|Q4KMG0|CDON_HUMAN Cell adhesion molecule-related/down-regulate... 104 3e-21
sp|Q90Z04|CDON_XENLA Cell adhesion molecule-related/down-regulate... 103 4e-21
sp|Q99M80|PTPRT_MOUSE Receptor-type tyrosine-protein phosphatase ... 103 4e-21
sp|Q9BWV1|BOC_HUMAN Brother of CDO OS=Homo sapiens OX=9606 GN=BOC... 103 4e-21
sp|P23467|PTPRB_HUMAN Receptor-type tyrosine-protein phosphatase ... 103 8e-21
sp|P06213|INSR_HUMAN Insulin receptor OS=Homo sapiens OX=9606 GN=... 102 8e-21
sp|O73798|IGF1R_XENLA Insulin-like growth factor 1 receptor OS=Xe... 102 9e-21
sp|Q9HD43|PTPRH_HUMAN Receptor-type tyrosine-protein phosphatase ... 101 1e-20
sp|P16620|PTP69_DROME Tyrosine-protein phosphatase 69D OS=Drosoph... 101 2e-20
sp|P35590|TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 OS=Ho... 100 3e-20
sp|Q8N9C0|IGS22_HUMAN Immunoglobulin superfamily member 22 OS=Hom... 100 3e-20
sp|Q1KL86|EPHA2_MACFA Ephrin type-A receptor 2 OS=Macaca fascicul... 100 4e-20
sp|Q32MD9|CDON_MOUSE Cell adhesion molecule-related/down-regulate... 100 4e-20
sp|B2RU80|PTPRB_MOUSE Receptor-type tyrosine-protein phosphatase ... 100 5e-20
sp|P19756|GHR_PIG Growth hormone receptor OS=Sus scrofa OX=9823 G... 99.2 5e-20
sp|Q60837|I12R1_MOUSE Interleukin-12 receptor subunit beta-1 OS=M... 99.5 5e-20
sp|Q06805|TIE1_BOVIN Tyrosine-protein kinase receptor Tie-1 OS=Bo... 99 5e-20
sp|P16144|ITB4_HUMAN Integrin beta-4 OS=Homo sapiens OX=9606 GN=I... 99.5 9e-20
sp|Q2Q0I9|FNDC1_RAT Fibronectin type III domain-containing protei... 99.2 1e-19
sp|Q95JF2|GHR_AILME Growth hormone receptor OS=Ailuropoda melanol... 97.2 2e-19
sp|O35158|CDON_RAT Cell adhesion molecule-related/down-regulated ... 98.0 2e-19
sp|P16310|GHR_RAT Growth hormone receptor OS=Rattus norvegicus OX... 97.2 2e-19
sp|P19941|GHR_RABIT Growth hormone receptor OS=Oryctolagus cunicu... 96.8 3e-19
sp|P54753|EPHB3_HUMAN Ephrin type-B receptor 3 OS=Homo sapiens OX... 97.6 3e-19
sp|Q78DX7|ROS1_MOUSE Proto-oncogene tyrosine-protein kinase ROS O... 98.0 3e-19
sp|P13590|NCAM1_CHICK Neural cell adhesion molecule 1 OS=Gallus g... 97.6 3e-19
sp|Q97Z97|Y1033_SACS2 Kelch domain-containing protein SSO1033 OS=... 96.8 3e-19
sp|Q91571|EPB1A_XENLA Ephrin type-B receptor 1-A OS=Xenopus laevi... 97.2 3e-19
sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo ... 97.2 3e-19
sp|Q6AZB0|BOC_MOUSE Brother of CDO OS=Mus musculus OX=10090 GN=Bo... 97.2 3e-19
sp|A2A863|ITB4_MOUSE Integrin beta-4 OS=Mus musculus OX=10090 GN=... 97.6 3e-19
sp|Q63132|ROS1_RAT Proto-oncogene tyrosine-protein kinase ROS OS=... 97.6 3e-19
sp|P54754|EPHB3_MOUSE Ephrin type-B receptor 3 OS=Mus musculus OX... 96.8 4e-19
sp|Q64632|ITB4_RAT Integrin beta-4 OS=Rattus norvegicus OX=10116 ... 97.2 4e-19
sp|Q07497|EPHB5_CHICK Ephrin type-B receptor 5 OS=Gallus gallus O... 96.8 5e-19
sp|P08922|ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS O... 97.2 5e-19
sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens OX... 96.5 6e-19
sp|P13591|NCAM1_HUMAN Neural cell adhesion molecule 1 OS=Homo sap... 96.1 6e-19
sp|P79108|GHR_BOSIN Growth hormone receptor OS=Bos indicus OX=991... 95.7 7e-19
sp|Q63HQ2|EGFLA_HUMAN Pikachurin OS=Homo sapiens OX=9606 GN=EGFLA... 95.7 1e-18
sp|O46600|GHR_BOVIN Growth hormone receptor OS=Bos taurus OX=9913... 94.9 1e-18
sp|P31836|NCAM1_BOVIN Neural cell adhesion molecule 1 OS=Bos taur... 95.3 1e-18
sp|P36335|NCA12_XENLA Neural cell adhesion molecule 1-B OS=Xenopu... 95.3 1e-18
sp|P08941|ROS1_CHICK Proto-oncogene tyrosine-protein kinase ROS O... 95.3 2e-18
sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mu... 94.5 3e-18
sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens OX... 94.2 3e-18
sp|Q60629|EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus musculus OX... 93.8 3e-18
sp|Q967D7|TUTL_DROME Protein turtle OS=Drosophila melanogaster OX... 94.2 3e-18
sp|P16882|GHR_MOUSE Growth hormone receptor OS=Mus musculus OX=10... 93.4 3e-18
sp|Q95ML5|GHR_SAIBB Growth hormone receptor OS=Saimiri boliviensi... 93.0 4e-18
sp|Q4VBE4|EGFLA_MOUSE Pikachurin OS=Mus musculus OX=10090 GN=Egfl... 93.8 4e-18
sp|Q28575|GHR_SHEEP Growth hormone receptor OS=Ovis aries OX=9940... 93.0 4e-18
sp|Q9YI66|TYRO3_DANRE Tyrosine-protein kinase receptor TYRO3 OS=D... 93.4 4e-18
sp|P13596|NCAM1_RAT Neural cell adhesion molecule 1 OS=Rattus nor... 93.0 6e-18
sp|Q02092|GHR_CHICK Growth hormone receptor OS=Gallus gallus OX=9... 91.8 8e-18
>sp|P40189|IL6RB_HUMAN Interleukin-6 receptor subunit beta OS=Homo
sapiens OX=9606 GN=IL6ST PE=1 SV=2
Length=918
Score = 1301 bits (3366), Expect = 0.0, Method: Composition-based stats.
Identities = 918/918 (100%), Positives = 918/918 (100%), Gaps = 0/918 (0%)
Query 1 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV 60
MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV
Sbjct 1 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV 60
Query 61 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI 120
NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI
Sbjct 61 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI 120
Query 121 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT
Sbjct 121 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL
Sbjct 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR
Sbjct 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN
Sbjct 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
Query 361 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD
Sbjct 361 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT
Sbjct 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD
Sbjct 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG
Sbjct 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK
Sbjct 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
Query 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN
Sbjct 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
Query 721 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS 780
TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS
Sbjct 721 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS 780
Query 781 ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV 840
ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV
Sbjct 781 ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV 840
Query 841 NEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEG 900
NEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEG
Sbjct 841 NEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEG 900
Query 901 MPKSYLPQTVRQGGYMPQ 918
MPKSYLPQTVRQGGYMPQ
Sbjct 901 MPKSYLPQTVRQGGYMPQ 918
>sp|Q00560|IL6RB_MOUSE Interleukin-6 receptor subunit beta OS=Mus
musculus OX=10090 GN=Il6st PE=1 SV=2
Length=917
Score = 1199 bits (3101), Expect = 0.0, Method: Composition-based stats.
Identities = 708/919 (77%), Positives = 796/919 (87%), Gaps = 3/919 (0%)
Query 1 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV 60
M + WL QAL FLTTES G+LL+PCGYI PE PVVQ SNFTA+CVLKE C+ +++V
Sbjct 1 MSAPRIWLAQALLFFLTTESIGQLLEPCGYIYPEFPVVQRGSNFTAICVLKEACLQHYYV 60
Query 61 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI 120
NA+YIVWKTNH +P+EQ T+INRT SSVTFTD+ ++QLTCNIL+FGQ+EQNVYG+T+
Sbjct 61 NASYIVWKTNHAAVPREQVTVINRTTSSVTFTDVVLPSVQLTCNILSFGQIEQNVYGVTM 120
Query 121 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
+SG PP+KP NL+CIVNEGK M C+WD GRET+LETN+TLKSEWAT KF DC++K T
Sbjct 121 LSGFPPDKPTNLTCIVNEGKNMLCQWDPGRETYLETNYTLKSEWATEKFPDCQSKHG--T 178
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
SC V Y Y+VNIEVWVEAENALGKV+S+ INFDPV KVKP PP+NLSV NSEELSSIL
Sbjct 179 SCMVSYMPTYYVNIEVWVEAENALGKVSSESINFDPVDKVKPTPPYNLSVTNSEELSSIL 238
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
KL+W + + ++ LK +IQYRTKDASTW Q+P EDT S R+SFTVQDLKPFTEYVFRIR
Sbjct 239 KLSWVSSGLGGLLDLKSDIQYRTKDASTWIQVPLEDTMSPRTSFTVQDLKPFTEYVFRIR 298
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
+K+ GKGYWSDWSEEASG TYEDRPS+ PSFWYK +PSH Q YR+V+L+WK LP EAN
Sbjct 299 SIKDSGKGYWSDWSEEASGTTYEDRPSRPPSFWYKTNPSHGQEYRSVRLIWKALPLSEAN 358
Query 361 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
GKILDYEV LT+ KS Q YTV T+LTVNLTNDRY+A+L RN VGKS AAVLTIP+
Sbjct 359 GKILDYEVILTQSKSVSQTYTVTGTELTVNLTNDRYVASLAARNKVGKSAAAVLTIPSPH 418
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
A + V++LKAFPKDN+LWVEWT P + V KYILEWCVLS+ APC+ DWQQED TV+RT
Sbjct 419 VTAAYSVVNLKAFPKDNLLWVEWTPPPKPVSKYILEWCVLSENAPCVEDWQQEDATVNRT 478
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
+LRG L ESKCY ITVTPV+A GPG ES+KAYLKQA P++GPTVRTKKVGKNEAVL WD
Sbjct 479 HLRGRLLESKCYQITVTPVFATGPGGSESLKAYLKQAAPARGPTVRTKKVGKNEAVLAWD 538
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
Q+PVD QNGFIRNY+I YRT +G E V+VDSSHTEYTLSSL+SDTLYMVRMAAYTDEGG
Sbjct 539 QIPVDDQNGFIRNYSISYRTSVGKEMVVHVDSSHTEYTLSSLSSDTLYMVRMAAYTDEGG 598
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK
Sbjct 599 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 658
Query 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEAN+KKP P+DLKS+DLFKKEK++
Sbjct 659 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANNKKPCPDDLKSVDLFKKEKVS 718
Query 721 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS 780
TEGHSSGIGGSSCMSSSRPSISS++ENES+Q+T+STVQYSTVVHSGYRHQVPSVQVFSRS
Sbjct 719 TEGHSSGIGGSSCMSSSRPSISSNEENESAQSTASTVQYSTVVHSGYRHQVPSVQVFSRS 778
Query 781 ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV 840
ESTQPLLDSEERPEDLQLVD VDGGD ILPRQ YFKQNCSQ E+ P+ISHFERS QV S
Sbjct 779 ESTQPLLDSEERPEDLQLVDSVDGGDEILPRQPYFKQNCSQPEACPEISHFERSNQVLSG 838
Query 841 NEEDFVRLK-QQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDE 899
NEEDFVRLK QQ+SDHISQ GS Q ++FQE S ADA G G +GQ+ERFE+VGME DE
Sbjct 839 NEEDFVRLKQQQVSDHISQPYGSEQRRLFQEGSTADALGTGADGQMERFESVGMETTIDE 898
Query 900 GMPKSYLPQTVRQGGYMPQ 918
+PKSYLPQTVRQGGYMPQ
Sbjct 899 EIPKSYLPQTVRQGGYMPQ 917
>sp|P40190|IL6RB_RAT Interleukin-6 receptor subunit beta OS=Rattus
norvegicus OX=10116 GN=Il6st PE=1 SV=1
Length=918
Score = 1184 bits (3063), Expect = 0.0, Method: Composition-based stats.
Identities = 722/919 (79%), Positives = 802/919 (87%), Gaps = 2/919 (0%)
Query 1 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV 60
M L+ WL+QAL IFLTTES G+L++PCGYI PE PVVQ SNFTA CVLKEKC+ + V
Sbjct 1 MSALRIWLMQALLIFLTTESIGQLVEPCGYIYPEFPVVQRGSNFTATCVLKEKCLQVYSV 60
Query 61 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI 120
NA YIVWKTNH +PKEQ T+INRTASSVTFTD+ N+QLTCNIL+FGQ+EQNVYGITI
Sbjct 61 NATYIVWKTNHVAVPKEQVTVINRTASSVTFTDVVFQNVQLTCNILSFGQIEQNVYGITI 120
Query 121 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
+SG PP+ P NLSCIVNEGK M C+ D GRET+LETN+TLKSEWAT KF DC+ K T
Sbjct 121 LSGYPPDIPTNLSCIVNEGKNMLCQLDPGRETYLETNYTLKSEWATEKFPDCRTKHGTS- 179
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
SC + Y+ +YFVNIEVWVEAENALG V+S+ INFDPV KVKP+PPHNLSV NSEELSSIL
Sbjct 180 SCMMGYTPIYFVNIEVWVEAENALGNVSSEPINFDPVDKVKPSPPHNLSVTNSEELSSIL 239
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
KL W N + S++ LK +IQYRTKDASTW Q+P EDT S R+SFTVQDLKPFTEYVFRIR
Sbjct 240 KLAWVNSGLDSILRLKSDIQYRTKDASTWIQVPLEDTVSPRTSFTVQDLKPFTEYVFRIR 299
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
+KE+GKGYWSDWSEEASG TYEDRPSKAPSFWYK++ +H Q YR+ +L+WKTLP EAN
Sbjct 300 SIKENGKGYWSDWSEEASGTTYEDRPSKAPSFWYKVNANHPQEYRSARLIWKTLPLSEAN 359
Query 361 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
GKILDYEV LT+ KS Q YTVN T+L VNLTN+RY+A+L RN+VGKS A VLTIP
Sbjct 360 GKILDYEVVLTQSKSVSQTYTVNGTELIVNLTNNRYVASLAARNVVGKSPATVLTIPGSH 419
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
F+A+HPV+DLKAFPKDN+LWVEWT P + V KYILEWCVLS+ +PCI DWQQEDGTV+RT
Sbjct 420 FKASHPVVDLKAFPKDNLLWVEWTPPSKPVNKYILEWCVLSENSPCIPDWQQEDGTVNRT 479
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
+LRG+L ESKCYLITVTPV+ GPGSPES+KAYLKQA PSKGPTVRTKKVGKNEAVLEWD
Sbjct 480 HLRGSLLESKCYLITVTPVFPGGPGSPESMKAYLKQAAPSKGPTVRTKKVGKNEAVLEWD 539
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
LPVDVQNGFIRNY+I YRT +G E V VDSSHTEYTLSSL+SDTLYMV MAAYT+EGG
Sbjct 540 HLPVDVQNGFIRNYSISYRTSVGKEMVVRVDSSHTEYTLSSLSSDTLYMVHMAAYTEEGG 599
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
KDGPEFTFTT KFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK
Sbjct 600 KDGPEFTFTTLKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 659
Query 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
SHIAQWSPHTPPRHNFNSKDQMYSD NFTDVSVVEIEAN+KKP P+DLKSLDLFKKEKI+
Sbjct 660 SHIAQWSPHTPPRHNFNSKDQMYSDANFTDVSVVEIEANNKKPCPDDLKSLDLFKKEKIS 719
Query 721 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS 780
TEGHSSGIGGSSCMSSSRPSISSS+ENES+Q+T+STVQYSTVVHSGYRHQVPSVQVFSRS
Sbjct 720 TEGHSSGIGGSSCMSSSRPSISSSEENESAQSTASTVQYSTVVHSGYRHQVPSVQVFSRS 779
Query 781 ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV 840
ESTQPLLDSEERPEDLQLVD VD GD ILPRQQYFKQ+CSQ +SPD+SHF RS QV S
Sbjct 780 ESTQPLLDSEERPEDLQLVDSVDSGDEILPRQQYFKQSCSQPGASPDVSHFGRSSQVPSG 839
Query 841 NEEDFVRLK-QQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDE 899
+EEDFVRLK QQ+SDHIS+ GS Q ++FQE S ADA G GT+GQ+ERFE+VGME A DE
Sbjct 840 SEEDFVRLKQQQVSDHISEPYGSEQRRLFQEGSVADALGTGTDGQIERFESVGMETAMDE 899
Query 900 GMPKSYLPQTVRQGGYMPQ 918
+ KSYLPQTVRQGGYMPQ
Sbjct 900 DISKSYLPQTVRQGGYMPQ 918
>sp|Q99062|CSF3R_HUMAN Granulocyte colony-stimulating factor receptor
OS=Homo sapiens OX=9606 GN=CSF3R PE=1 SV=1
Length=836
Score = 593 bits (1528), Expect = 0.0, Method: Composition-based stats.
Identities = 211/804 (26%), Positives = 336/804 (42%), Gaps = 58/804 (7%)
Query 6 TWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYI 65
TW AL I L S L+ CG+IS +P+V L TA C++K+ C I
Sbjct 10 TW--AALIILLLPGS----LEECGHISVSAPIVHLGDPITASCIIKQNCSHL--DPEPQI 61
Query 66 VWKTNHFTIP--KEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISG 123
+W+ P ++Q S +T + L+C L +G Q + + + +G
Sbjct 62 LWRLGAELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSC-CLNWGNSLQILDQVELRAG 120
Query 124 LPPEKPKNLSCIVN-EGKKMRCEWDGGRETHLETNFTLK-------SEWATHKFADCKAK 175
PP P NLSC++N + C+W+ G ETHL T+FTLK + DC K
Sbjct 121 YPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPK 180
Query 176 RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
C + + N+ +WV+AENALG S + DP+ VK PP ++ S E
Sbjct 181 DGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPE 240
Query 236 LSS----ILKLTWTNPSIKSVIILKYNIQYRT-KDASTWSQIPPEDTASTRSSFTVQDLK 290
+ L+L W I K ++++ + ++W+ + P + + + L
Sbjct 241 AAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEA--LQYELCGLL 298
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
P T Y +IRC++ G+WSDWS T E P+ W++ RTVQL
Sbjct 299 PATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWR---QRQLDPRTVQLF 355
Query 351 WKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT---KLTVNLTNDRYLATLTVRNLVG 407
WK +P E +G+I Y V+ + T T +L ++ L N G
Sbjct 356 WKPVPLEEDSGRIQGYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAG 415
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
S + A + + P LWV W P + Y++EW + A
Sbjct 416 TSRPTPVVFSESRGPALTRLHAMARDPHS--LWVGWEPPNPWPQGYVIEWGLGPPSASNS 473
Query 468 TD-WQQE-DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
W+ E +G L+ N+ + Y I VTP+Y D G + + AY ++ PS P +
Sbjct 474 NKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPEL 533
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
K +GK A LEW P ++ + +YTIF+ + +++S + L L
Sbjct 534 HLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSFSAILNASSRGFVLHGLEPA 593
Query 586 TLYMVRMAAYTDEGGKDGPEFTFT--TPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNK 643
+LY + + A + G + T TP+ ++ I + + L L C
Sbjct 594 SLYHIHLMAASQAGATNSTVLTLMTLTPEGSELHIILGLFGLLLLLTCLCGTAWLCCSPN 653
Query 644 RDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKP 703
R K +WP+VPDP+ S + W P F Q+ G + +E ++KKP
Sbjct 654 R---KNPLWPSVPDPAHSSLGSWVPTIMEEDAF----QLPGLGTPPITKLTVLEEDEKKP 706
Query 704 FPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVV 763
P + S + + + T + + G S++P +S TS V Y ++
Sbjct 707 VPWE--SHNSSETCGLPTLVQTYVLQGDPRAVSTQP--------QSQSGTSDQVLYGQLL 756
Query 764 HSGYRHQVPSVQVFSRSESTQPLL 787
S P + R +STQPLL
Sbjct 757 GSPTS---PGPGHYLRCDSTQPLL 777
>sp|P40223|CSF3R_MOUSE Granulocyte colony-stimulating factor receptor
OS=Mus musculus OX=10090 GN=Csf3r PE=1 SV=2
Length=837
Score = 575 bits (1481), Expect = 0.0, Method: Composition-based stats.
Identities = 194/802 (24%), Positives = 324/802 (40%), Gaps = 54/802 (7%)
Query 8 LVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVW 67
L IFL + L+ CG+I PVV+L A C + C I+W
Sbjct 9 LTGVTLIFLLLPRS---LESCGHIEISPPVVRLGDPVLASCTISPNCSKL--DQQAKILW 63
Query 68 KTNHFTIPK--EQYTIINRTASS-VTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGL 124
+ I Q+ + + T S +T + L C ++ + Q + + +G
Sbjct 64 RLQDEPIQPGDRQHHLPDGTQESLITLPHLNYTQAFLFC-LVPWEDSVQLLDQAELHAGY 122
Query 125 PPEKPKNLSCIVN-EGKKMRCEWDGGRETHLETNFTLK-------SEWATHKFADCKAKR 176
PP P NLSC+++ + C+W+ G ETHL T+F LK ++ DC AK+
Sbjct 123 PPASPSNLSCLMHLTTNSLVCQWEPGPETHLPTSFILKSFRSRADCQYQGDTIPDCVAKK 182
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH----NLSVIN 232
+ + + + +WV+AEN LG S + DP+ VK PP ++
Sbjct 183 RQNNCSIPRKNLLLYQYMAIWVQAENMLGSSESPKLCLDPMDVVKLEPPMLQALDIGPDV 242
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTK-DASTWSQIPPEDTASTRSSFTVQDLKP 291
L L+W + + ++Y+ + + W+ + S++ F + L
Sbjct 243 VSHQPGCLWLSWKPWKPSEYMEQECELRYQPQLKGANWTLV--FHLPSSKDQFELCGLHQ 300
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
Y ++RC++ G+WS WS P+ W + G +VQL W
Sbjct 301 APVYTLQMRCIRSSLPGFWSPWSPGLQLRPTMKAPTIRLDTWCQKKQLD-PGTVSVQLFW 359
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQN-YTVNATKLTV--NLTNDRYLATLTVRNLVGK 408
K P E +G+I Y ++ + Q+ + N T+L+ L ++ TL N G
Sbjct 360 KPTPLQEDSGQIQGYLLSWSSPDHQGQDIHLCNTTQLSCIFLLPSEAQNVTLVAYNKAGT 419
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRESVKKYILEWCVLSDK-APC 466
S + + A V L A +D N +WV+W P + Y++EW + S
Sbjct 420 SSPTTVVFLENEGPA---VTGLHAMAQDLNTIWVDWEAPSLLPQGYLIEWEMSSPSYNNS 476
Query 467 ITDWQQED-GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
W E G + L+ N+ + Y ITV P+Y G P ++ + + P P +
Sbjct 477 YKSWMIEPNGNITGILLKDNINPFQLYRITVAPLYPGIVGPPVNVYTFAGERAPPHAPAL 536
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
K VG A LEW + + +YTIF+ + +V ++ S ++ L L
Sbjct 537 HLKHVGTTWAQLEWVPEAPRLGMIPLTHYTIFWADAGDHSFSVTLNISLHDFVLKHLEPA 596
Query 586 TLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRD 645
+LY V + A + G + T T ++ + +CL L TT + C +R
Sbjct 597 SLYHVYLMATSRAGSTNSTGLTLRT--LDPSDLNIFLGILCLVLLSTTCVVTWLCCKRRG 654
Query 646 LIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFP 705
K W +VPDP+ S ++ W P F + D + ++ + DKKP
Sbjct 655 --KTSFWSDVPDPAHSSLSSWLPTIMTEETFQLPS--FWDSSVPSITKITELEEDKKPTH 710
Query 706 EDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHS 765
D +S + G + + + I S++++ T V Y V+ S
Sbjct 711 WDSES---------SGNGSLPALVQAYVLQGDPREI--SNQSQPPSRTGDQVLYGQVLES 759
Query 766 GYRHQVPSVQVFSRSESTQPLL 787
P V + RS+STQPLL
Sbjct 760 PTS---PGVMQYIRSDSTQPLL 778
>sp|Q5XNR9|LIFR_CANLF Leukemia inhibitory factor receptor OS=Canis
lupus familiaris OX=9615 GN=LIFR PE=2 SV=1
Length=1097
Score = 504 bits (1297), Expect = 2e-161, Method: Composition-based stats.
Identities = 184/813 (23%), Positives = 315/813 (39%), Gaps = 94/813 (12%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCM--DYFHVNANYIVWKTNHFTIPKEQYTIINRTASS 88
+ P+ V+ + S+ T CV +EK + N I + I ++ + ++
Sbjct 254 VFPQDKVILVGSDITFCCVTQEKVLSAQIGQTNCPLIHLDGENVAIKIHNISVSANSGTN 313
Query 89 VTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG 148
V FT E N++G I G PP+ P+ ++C + K++ C W+
Sbjct 314 VVFT------------------TEDNIFGTVIFVGYPPDIPQKVNCETYDLKEIVCTWNP 355
Query 149 GRETHL----ETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN---IEVWVEAE 201
GR T L T++TL ++ + + PT+ + N + A
Sbjct 356 GRPTALVGPRNTSYTLFESFSGKYVR--FKRVEAPTNESYQLFFQMRPNQEIYNFTLNAR 413
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
N LG+ S I + KV P P ++ V + S+ + L+W P + I L I+
Sbjct 414 NPLGRSEST-ILINITEKVYPRIPTSIKVKDIN--STAVMLSWHLPGNFAKIKLLCQIEI 470
Query 262 -RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
+T + + ++ V L P+T Y FRIRC E WS WS E +
Sbjct 471 NKTNSVQELRNVTIKGVENSSYLVAVDKLNPYTIYTFRIRCSTETF-WKWSKWSNEKKYL 529
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--RWKSHLQ 378
T E PSK P W + + + + + WK LP EANGKIL Y V+ + L
Sbjct 530 TTEAIPSKGPDTWRE----WSSDGKNLIIYWKPLPINEANGKILSYNVSCSLDEETQSLS 585
Query 379 NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA---AVLTIPACDFQATHPVMDLKAFPK 435
K + L + Y+ ++ +N VG S A + IP D + +A
Sbjct 586 EIPDPQHKAELQLDKNDYIISVVAKNSVGSSPPSKIASMEIPNDDLKVE------QAVGM 639
Query 436 DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN-LAESKCYLI 494
N + + W Y+++WC S PC+ DW++ + + Y
Sbjct 640 GNGILLTWNYDPNMTCDYVIKWCNSSRSEPCLMDWKKVPSNSTEAVIESDQFRPGVRYSF 699
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
+ +G SI Y+++ P P + + +++W+ +PV+ GF+R Y
Sbjct 700 FLYGCRNEGYQLLRSIIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGY 759
Query 555 TIFY----------RTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
++ R + + + V D S ++ L T Y + + AYTD G
Sbjct 760 LFYFEKGERDTSKIRGLESGRSDIKVKNITDLSQKTLRIADLQGKTSYHLVLRAYTDGGM 819
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
T + + G I AI++PV +A ++ + +L C+ KR+ IK+ +P++P+P
Sbjct 820 GPEKSMFVVTKENSVGLIIAILIPVAVAVIVGVVTSIL-CYRKREWIKETFYPDIPNPEN 878
Query 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
Q+ NS + T +V +E P ED + + +
Sbjct 879 CKALQFQKSVCE---GNSALKTLEMNPCTPNNVEVLETRSAVPKIEDTEIISPIAER--P 933
Query 721 TEGHSSGIGGSSCMSSSRPSISSSDENESS--QNTSSTVQYSTVVHSGYRHQVPSVQVFS 778
E + +S P I N + +S V Y +
Sbjct 934 EESSDAEAENHVVVSYCPPVIEEETPNPGADEAGGASQVVYIDI---------------- 977
Query 779 RSESTQPLLDSEERPEDLQLVDHVDGGDGILPR 811
Q + + +PE+ Q D V GG G P+
Sbjct 978 -----QSMYQPQAKPEEEQENDPV-GGAGYKPQ 1004
Score = 86.8 bits (213), Expect = 5e-16, Method: Composition-based stats.
Identities = 69/505 (14%), Positives = 146/505 (29%), Gaps = 72/505 (14%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCK-AKRDTPTSCTVD 185
P++L CI N + C W T + + E +H + P D
Sbjct 48 GAPRDLKCITNNLRVWDCSWKAPSAAGHGTVYEICIENRSHSCYQSEKTNTKIPALLPGD 107
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ + N + K T + N + P+ P L++ +++ +S + L W
Sbjct 108 HEITINRLYDF----GNPISKFTLNEKNVSLI----PDTPEILNL-SADFSTSTIHLKWN 158
Query 246 NPS--IKSVIILKYNIQYRTKDA-------STWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
+ + + + I+ K+ + + + +DT S + L+ +
Sbjct 159 DRGSVFPHQLTVIWEIKILRKENMEIVKLITHNTTVNGKDTVHHWSWTSDMPLE-CAIHS 217
Query 297 FRIRCMKED----GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
IRC +D G+ WSDWS + W + V L
Sbjct 218 VGIRCYVDDPHFSGRKEWSDWSPLKNI------------SWSPDSQTKVFPQDKVIL--- 262
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
+ ++T + D + + N+ +++
Sbjct 263 -----------VGSDITFCCVTQEKVLSAQIGQTNCPLIHLDGENVAIKIHNISVSANSG 311
Query 413 VLTIPACDFQATHPVMDLKAFPKD------------NMLWVEWTT--PRESVKKYILEWC 458
+ + V+ + +P D + W P V +
Sbjct 312 TNVVFTTEDNIFGTVIFV-GYPPDIPQKVNCETYDLKEIVCTWNPGRPTALVGPRNTSYT 370
Query 459 VLSD-KAPCITDWQQEDGTVHRTYLRGNLAESK-CYLITVTPVYADGPGSPESIKAYLKQ 516
+ + + E T L + ++ Y T+ G + ++
Sbjct 371 LFESFSGKYVRFKRVEAPTNESYQLFFQMRPNQEIYNFTLNARNPLGRSESTILINITEK 430
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR-NYTIFYRTIIGNETAVNVDSSHT 575
P +++ K + +L W LP + + I + V +
Sbjct 431 VYPRIPTSIKVKDINSTAVMLSW-HLPGNFAKIKLLCQIEINKTNSVQELRNVTIKGVEN 489
Query 576 E---YTLSSLTSDTLYMVRMAAYTD 597
+ L T+Y R+ T+
Sbjct 490 SSYLVAVDKLNPYTIYTFRIRCSTE 514
>sp|Q9BEG2|I12R2_BOVIN Interleukin-12 receptor subunit beta-2
OS=Bos taurus OX=9913 GN=IL12RB2 PE=2 SV=1
Length=861
Score = 495 bits (1273), Expect = 2e-160, Method: Composition-based stats.
Identities = 166/721 (23%), Positives = 280/721 (39%), Gaps = 46/721 (6%)
Query 12 LFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEK--CMDYFHVNANYIVWKT 69
+ + L ++ ++ S V+ L S C LK K C+ N I++K
Sbjct 15 IIMLLLVKAKIDVCKRGDVTVQPSHVISLGSAVNISCSLKPKQGCLPSSSFN-KLILYKF 73
Query 70 NHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKP 129
+ + +++ ++ T + C + E + G I G+ PE+P
Sbjct 74 DRRIYVQHGHSLSSQVKGLPLGTTL------FVCKLACSSSDEIRICGAEISVGVVPEQP 127
Query 130 KNLSCI-VNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFAD--CKAKRDTPTSCTVDY 186
+NLSCI E + C W GR+THL T +TL+ + C ++
Sbjct 128 RNLSCIQKGERGTVTCTWHRGRDTHLYTAYTLQLNGPKNLTWQKQCNDHYCDHLDLGINL 187
Query 187 STVYF-VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ + V V A N+LG +S +F + V+P PP ++ + L W
Sbjct 188 TPESLESSYTVKVTAINSLGSASSFPFSFTLLDIVRPLPPWDIRIKFVNASVDRCTLLWR 247
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
+ ++L ++YR ++ +W+ + + + + + DLKPFTEY F+I
Sbjct 248 D----EGLVLLNRLRYRPINSRSWNMV---NVTNAKGRHDLLDLKPFTEYEFQISSKLHL 300
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
KG WSDWSE T E+ P + WY + + + L WK L EA GKIL
Sbjct 301 YKGSWSDWSESLRTQTPEEEPIGMLNVWY-MRQHIDYNRQQISLFWKNLSLSEARGKILH 359
Query 366 YEVTLTRWKS---HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA-CDF 421
Y+VTL + LQN T + + V + A ++ N G S + I C
Sbjct 360 YQVTLQKVAGGEITLQNITEHTSWTWVIPRTGNWAAAVSAANSKGSSLPTRINITDLCGA 419
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRE---SVKKYILEWCVLSDKA--PCITDWQQEDGT 476
+ P L + L V WT P + +V++Y++EW L A W
Sbjct 420 ELLAPQQVLAKSEGMDKLMVTWTPPEKATAAVQEYVVEWRELHPGAGMQPPLGWLWSPPY 479
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAV 536
+ N+ CY I V + D G S + + P GP + K +
Sbjct 480 RLSALISENIKPYICYEIRVHALAGDQGGC-NSTRGNSQHKAPLSGPHINAISEEKGSVL 538
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+ WD++P Q G I +Y I+++ N + S + + SL Y++ M
Sbjct 539 ISWDEIPAREQMGCILHYRIYWKERDSNSQPQLCEIPYRISPNSHPIDSLQPRVTYVLWM 598
Query 593 AAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVP-VCLAFLLTTLLGVLFCFNKRDLI--- 647
A T G G E F + V P +C+A ++ +L + CF ++ +
Sbjct 599 TALTAAGESPQGNEREFCLQ--GKANWSTFVAPSICMAVIMVGVLS-MRCFRQKVFVLLL 655
Query 648 ---KKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPF 704
+ +PDP+ S A+ P + + + + I +
Sbjct 656 ALRPQWCSKEIPDPANSTWAKKYPIVEEKTQLALDRLLTEWPTPEEPEPLVINEVLCRVT 715
Query 705 P 705
P
Sbjct 716 P 716
>sp|Q8MJS1|I12R2_PIG Interleukin-12 receptor subunit beta-2 OS=Sus
scrofa OX=9823 GN=IL12RB2 PE=2 SV=1
Length=861
Score = 494 bits (1271), Expect = 3e-160, Method: Composition-based stats.
Identities = 191/851 (22%), Positives = 325/851 (38%), Gaps = 91/851 (11%)
Query 7 WLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEK--CMDYFHVNANY 64
W + + + L ++ ++ S V+ L S C LK + C+ +N
Sbjct 10 WALIFIIMSLLVKAKIDVCKRGDVTVQPSHVISLGSAVNISCSLKPRQGCLQVSSLN-KL 68
Query 65 IVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGL 124
I+++ + + +++ ++ T + C + + E + G I G+
Sbjct 69 ILYRFHRRIHFQRGHSLSSQVTGLPLGTTL------FVCKLACSSKEEIRICGAEISVGV 122
Query 125 PPEKPKNLSC-IVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
PE+P+N+SC E + C WD GR+THL T +TL+ + C+
Sbjct 123 VPEQPQNVSCMQKGERGTVACSWDRGRDTHLYTAYTLQ--------LNGPKNLTWQKQCS 174
Query 184 VDYSTVYFV-----------NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
Y + + V A N+LG +S F + V+P PP ++ +
Sbjct 175 DYYCDSLDLGINLPPESPESSYTAQVTAINSLGTASSLPSTFTFLDVVRPLPPWDIRIKC 234
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
S L W + ++L ++YR + +W+ + + + + + DLKPF
Sbjct 235 VNASVSTCTLQWRD----EGLVLLNRLRYRPVYSRSWNMV---NATNAKGRHDLVDLKPF 287
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
TEY F+I KG WSDWSE T E P+ WY + + + L WK
Sbjct 288 TEYEFQISSKPHLQKGRWSDWSESLRTQTPEKEPTGMLDVWY-MKQHIDYKRQQISLFWK 346
Query 353 TLPPFEANGKILDYEVTLT---RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
L EA GKIL Y+VTL + LQN T + + A ++ N G S
Sbjct 347 NLSLSEARGKILHYQVTLQEVAEGNATLQNITERNSWTWTIPRTGIWAAAVSAANSKGSS 406
Query 410 DAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRE---SVKKYILEWCVLSDKA- 464
+ I + A P + L V+WT+P E +V++Y++EW L +
Sbjct 407 LPTRINIADLCGAGLLAPQQVSANPEGSDNLLVKWTSPGEGATAVQEYVVEWRELHLRGG 466
Query 465 -PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
W + T + N+ CY I V + D G SI+ LK P GP
Sbjct 467 MQPPLSWLRSPPYNTSTLISDNIKPYICYEIRVHALSGDQGGC-SSIRGDLKHKAPLSGP 525
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTL 579
+ K ++ WD++P Q G I +Y I+++ + + S + +
Sbjct 526 HINAISEEKGSILISWDEIPAQEQMGCILHYRIYWKERDSDSQPQLCEIPYRVSPKSHPI 585
Query 580 SSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVP-VCLAFLLTTLLGV 637
+SL Y++ M A T G G E F + V P +C+A + +
Sbjct 586 NSLQPRVTYVLWMTALTAAGESPQGNEREFCL--QGKANWSTFVAPSICIAVITVGVFS- 642
Query 638 LFCFNKRDLI----KKHIWP--NVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDV 691
+ CF ++ + + W +PDP+ S A+ P + S D++ +D +
Sbjct 643 MRCFRQKVFVLLLALRPQWCSREIPDPANSTWAKKYPIVEEKKQL-SLDRLLADWPTPEE 701
Query 692 SV-VEIEANDKKPFP---------EDLKSLDL---FKKEKINTEGHSSGIGGSSCMSSSR 738
+ I + P K L E+ SS + + +
Sbjct 702 PEPLVINEVLPQVTPVFRRPHHPNWPGKGQRLQGRHASEEDTGSSASSPPPPRALTAETG 761
Query 739 PSISSSD---ENESSQNTSSTVQYSTVV-------HSGYRHQVPSVQVFSRSESTQPLLD 788
P++ + V + TV+ H GY +PS + S P+ D
Sbjct 762 PAVDLYKVLGSRRPDSKPGNPVSHLTVLPVDYLPTHEGY---LPSNMDYLPSHEA-PITD 817
Query 789 S-EERPEDLQL 798
S EE P+ + L
Sbjct 818 SLEELPQHISL 828
>sp|P42702|LIFR_HUMAN Leukemia inhibitory factor receptor OS=Homo
sapiens OX=9606 GN=LIFR PE=1 SV=1
Length=1097
Score = 497 bits (1278), Expect = 1e-158, Method: Composition-based stats.
Identities = 179/814 (22%), Positives = 317/814 (39%), Gaps = 96/814 (12%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMD--YFHVNANYIVWKTNHFTIPKEQYTIINRTASS 88
+ P+ V+ + S+ T CV +EK + H N I + I ++ + ++
Sbjct 254 VFPQDKVILVGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIKIRNISVSASSGTN 313
Query 89 VTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG 148
V FT E N++G I +G PP+ P+ L+C ++ K++ C W+
Sbjct 314 VVFT------------------TEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNP 355
Query 149 GRETHL----ETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN---IEVWVEAE 201
GR T L T++TL ++ + + PT+ + N + A
Sbjct 356 GRVTALVGPRATSYTLVESFSGKYVR--LKRAEAPTNESYQLLFQMLPNQEIYNFTLNAH 413
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
N LG+ S I + KV P+ P + V + S+ +KL+W P + I I+
Sbjct 414 NPLGRSQST-ILVNITEKVYPHTPTSFKVKDIN--STAVKLSWHLPGNFAKINFLCEIEI 470
Query 262 RTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
+ ++ + + ++ + L P+T Y FRIRC E WS WS + +
Sbjct 471 KKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTFRIRCSTETF-WKWSKWSNKKQHL 529
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--RWKSHLQ 378
T E PSK P W + + + + + WK LP EANGKIL Y V+ + L
Sbjct 530 TTEASPSKGPDTWRE----WSSDGKNLIIYWKPLPINEANGKILSYNVSCSSDEETQSLS 585
Query 379 NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA---AVLTIPACDFQATHPVMDLKAFPK 435
K + L + Y+ ++ +N VG S A + IP D + +
Sbjct 586 EIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSKIASMEIPNDDLKIE------QVVGM 639
Query 436 DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN-LAESKCYLI 494
+ + W Y+++WC S PC+ DW++ T + + Y
Sbjct 640 GKGILLTWHYDPNMTCDYVIKWCNSSRSEPCLMDWRKVPSNSTETVIESDEFRPGIRYNF 699
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
+ G S+ Y+++ P P + + +++W+ +PV+ GF+R Y
Sbjct 700 FLYGCRNQGYQLLRSMIGYIEELAPIVAPNFTVEDTSADSILVKWEDIPVEELRGFLRGY 759
Query 555 TIFYRTIIGNETAVNV--------------DSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
++ + + + V D S ++ L T Y + + AYTD G
Sbjct 760 LFYFGKGERDTSKMRVLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGV 819
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
T + + G I AI++PV +A ++ + +L C+ KR+ IK+ +P++P+P
Sbjct 820 GPEKSMYVVTKENSVGLIIAILIPVAVAVIVGVVTSIL-CYRKREWIKETFYPDIPNPEN 878
Query 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
Q+ +S + T +V +E P ED + + +
Sbjct 879 CKALQFQKSVCE---GSSALKTLEMNPCTPNNVEVLETRSAFPKIEDTEIISPVAERP-- 933
Query 721 TEGHSSGIGGSSCMSSSRPSISSSDENESS---QNTSSTVQYSTVVHSGYRHQVPSVQVF 777
E S + + S P I + + ++ V Y V
Sbjct 934 -EDRSDAEPENHVVVSYCPPIIEEEIPNPAADEAGGTAQVIYIDV--------------- 977
Query 778 SRSESTQPLLDSEERPEDLQLVDHVDGGDGILPR 811
Q + + +PE+ Q D V GG G P+
Sbjct 978 ------QSMYQPQAKPEEEQENDPV-GGAGYKPQ 1004
Score = 98.8 bits (244), Expect = 1e-19, Method: Composition-based stats.
Identities = 70/503 (14%), Positives = 144/503 (29%), Gaps = 68/503 (14%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
P +L C+ N + C W T T++ + E + + ++
Sbjct 48 GAPHDLKCVTNNLQVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEK-------TSIKI 100
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ + E+ + + + G TS + + P+ P L++ +++ +S L L W +
Sbjct 101 PALSHGDYEITINSLHDFGSSTSKFTLNEQNVSLIPDTPEILNL-SADFSTSTLYLKWND 159
Query 247 PS--IKSVIILKYNIQYRTKDA-------STWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ + I+ K++ + + + +DT S + L+ +
Sbjct 160 RGSVFPHRSNVIWEIKVLRKESMELVKLVTHNTTLNGKDTLHHWSWASDMPLE-CAIHFV 218
Query 298 RIRCMKED----GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
IRC ++ G WSDWS + W + V L
Sbjct 219 EIRCYIDNLHFSGLEEWSDWSPVKNI------------SWIPDSQTKVFPQDKVIL---- 262
Query 354 LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRN-LVGKSDAA 412
+ ++T + + D + +RN V S
Sbjct 263 ----------VGSDITFCCVSQEKVLSALIGHTNCPLIHLDGENVAIKIRNISVSASSGT 312
Query 413 VLTIPACD----------FQATHPVMDLKAFPKDNMLWVEWTT--PRESVKKYILEWCVL 460
+ D + P + W V + ++
Sbjct 313 NVVFTTEDNIFGTVIFAGYPPDTPQQLNCETHDLKEIICSWNPGRVTALVGPRATSYTLV 372
Query 461 SD-KAPCITDWQQEDGTVHRTYLRGNLAESK-CYLITVTPVYADGPGSPESIKAYLKQAP 518
+ + E T L + ++ Y T+ G + ++
Sbjct 373 ESFSGKYVRLKRAEAPTNESYQLLFQMLPNQEIYNFTLNAHNPLGRSQSTILVNITEKVY 432
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG-FIRNYTIFYRTIIGNETAVNVDSSHTE- 576
P + + K + L W LP + F+ I + + V +
Sbjct 433 PHTPTSFKVKDINSTAVKLSW-HLPGNFAKINFLCEIEIKKSNSVQEQRNVTIKGVENSS 491
Query 577 --YTLSSLTSDTLYMVRMAAYTD 597
L L TLY R+ T+
Sbjct 492 YLVALDKLNPYTLYTFRIRCSTE 514
>sp|P97378|I12R2_MOUSE Interleukin-12 receptor subunit beta-2
OS=Mus musculus OX=10090 GN=Il12rb2 PE=1 SV=1
Length=874
Score = 480 bits (1235), Expect = 1e-154, Method: Composition-based stats.
Identities = 161/719 (22%), Positives = 284/719 (39%), Gaps = 52/719 (7%)
Query 12 LFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVL--KEKCMDYFHVNANYIVWKT 69
LF++L ++ ++ +PV+ L S C L K+ C Y N ++
Sbjct 15 LFMWLLIKANIDVCKLGTVTVQPAPVIPLGSAANISCSLNPKQGCSHYPSSNELILLKFV 74
Query 70 NHFTIPK-EQYTIINRTASSVTF--TDIASLNIQLTCNILTFGQLEQN---VYGITIISG 123
N + + + T S TF T+++ C + ++ V G+ I G
Sbjct 75 NDVLVENLHGKKVHDHTGHSSTFQVTNLSLGMTLFVCKLNCSNSQKKPPVPVCGVEISVG 134
Query 124 LPPEKPKNLSCIV-NEGKKMRCEWDGGRETHLETNFTLKSE-----WATHKF-----ADC 172
+ PE P+N+SC+ E + C W+ G+ T+L+TN+TL+ + +C
Sbjct 135 VAPEPPQNISCVQEGENGTVACSWNSGKVTYLKTNYTLQLSGPNNLTCQKQCFSDNRQNC 194
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
+ D + + D + F+ V V A N LG +S F + V P PP ++ +
Sbjct 195 N-RLDLGINLSPDLAESRFI---VRVTAINDLGNSSSLPHTFTFLDIVIPLPPWDIRINF 250
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
S L W + ++ ++Y+ ++++W+ + + + ++DL+PF
Sbjct 251 LNASGSRGTLQWEDEGQ----VVLNQLRYQPLNSTSWNMVNATNAKGK---YDLRDLRPF 303
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
TEY F+I G WS+WSE T E+ P WY + + + L WK
Sbjct 304 TEYEFQISSKLHLSGGSWSNWSESLRTRTPEEEPVGILDIWY-MKQDIDYDRQQISLFWK 362
Query 353 TLPPFEANGKILDYEVTLTR--WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD 410
+L P EA GKIL Y+VTL K+ LQN T + + V + A+++ N G S
Sbjct 363 SLNPSEARGKILHYQVTLQEVTKKTTLQNTTRHTSWTRVIPRTGAWTASVSAANSKGASA 422
Query 411 AAVLTIPACDFQATHPVMDLKA-FPKDNMLWVEWTTPRE---SVKKYILEWCVLSDKAPC 466
+ I + A + + V W P++ +V++YI+EW L +
Sbjct 423 PTHINIVDLCGTGLLAPHQVSAKSENMDNILVTWQPPKKADSAVREYIVEWRALQPGSIT 482
Query 467 I--TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
W + + N+ CY I V + ++ G SI+ K P GP
Sbjct 483 KFPPHWLRIPPDNMSALISENIKPYICYEIRVHAL-SESQGGCSSIRGDSKHKAPVSGPH 541
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII----GNETAVNVDSSHTEYTLS 580
+ K + W +P Q G I +Y I+++ + S + +S
Sbjct 542 ITAITEKKERLFISWTHIPFPEQRGCILHYRIYWKERDSTAQPELCEIQYRRSQNSHPIS 601
Query 581 SLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLF 639
SL Y++ M A T G G E F P+ ++ +C+A + + +
Sbjct 602 SLQPRVTYVLWMTAVTAAGESPQGNEREFC-PQGKANWKAFVISSICIAIITVGTFSIRY 660
Query 640 CFNKRDLIKKHIWPN-----VPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSV 693
K + + P +PDP+ S + P + + D + +
Sbjct 661 FRQKAFTLLSTLKPQWYSRTIPDPANSTWVKKYPILEEKIQLPT-DNLLMAWPTPEEPE 718
>sp|Q99665|I12R2_HUMAN Interleukin-12 receptor subunit beta-2
OS=Homo sapiens OX=9606 GN=IL12RB2 PE=1 SV=1
Length=862
Score = 471 bits (1211), Expect = 2e-151, Method: Composition-based stats.
Identities = 170/732 (23%), Positives = 277/732 (38%), Gaps = 68/732 (9%)
Query 12 LFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEK--CMDYFHVNANYIVWKT 69
+ +L ++ + S V+ L S C LK + C Y N I++K
Sbjct 15 IITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITCSLKPRQGCFHYSRRN-KLILYKF 73
Query 70 NHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKP 129
+ +++ ++ T + C + E + G I G+ PE+P
Sbjct 74 DRRINFHHGHSLNSQVTGLPLGTTL------FVCKLACINSDEIQICGAEIFVGVAPEQP 127
Query 130 KNLSCI-VNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYST 188
+NLSCI E + C W+ GR+THL T +TL+ C Y
Sbjct 128 QNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSG--------PKNLTWQKQCKDIYCD 179
Query 189 VYFV-----------NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
N V A N+LG +S F + V+P PP ++ + +
Sbjct 180 YLDFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIKFQKASV 239
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
S L W + ++L ++YR ++ W+ + + + + DLKPFTEY F
Sbjct 240 SRCTLYWRD----EGLVLLNRLRYRPSNSRLWNMV---NVTKAKGRHDLLDLKPFTEYEF 292
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW---YKIDPSHTQGYRTVQLVWKTL 354
+I KG WSDWSE T E+ P+ W ID S Q + L WK L
Sbjct 293 QISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQ----ISLFWKNL 348
Query 355 PPFEANGKILDYEVTLTR---WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA 411
EA GKIL Y+VTL K+ QN T + + TV + ++ N G S
Sbjct 349 SVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSKGSSLP 408
Query 412 AVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRES---VKKYILEWCVLSDKA--P 465
+ I + A + + + V W PR+ V++Y++EW L
Sbjct 409 TRINIMNLCEAGLLAPRQVSANSEGMDNILVTWQPPRKDPSAVQEYVVEWRELHPGGDTQ 468
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
+W + + N+ CY I V + D G SI K P GP +
Sbjct 469 VPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQGGC-SSILGNSKHKAPLSGPHI 527
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTLSS 581
K ++ W+ +PV Q G + +Y I+++ N + S + ++S
Sbjct 528 NAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINS 587
Query 582 LTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVP-VCLAFLLTTLLGVLF 639
L Y++ M A T G G E F + A V P +C+A ++ + +
Sbjct 588 LQPRVTYVLWMTALTAAGESSHGNEREFCL--QGKANWMAFVAPSICIAIIMVGIFSTHY 645
Query 640 CFNKRDLIKKHIWPN-----VPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSV- 693
K ++ + P +PDP+ S A+ P + D++ D +
Sbjct 646 FQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQL-PLDRLLIDWPTPEDPEP 704
Query 694 VEIEANDKKPFP 705
+ I + P
Sbjct 705 LVISEVLHQVTP 716
>sp|O70535|LIFR_RAT Leukemia inhibitory factor receptor OS=Rattus
norvegicus OX=10116 GN=Lifr PE=2 SV=1
Length=1093
Score = 475 bits (1221), Expect = 3e-150, Method: Composition-based stats.
Identities = 184/840 (22%), Positives = 317/840 (38%), Gaps = 91/840 (11%)
Query 29 GYISPESPVVQLHSNFTAVCVLKEKCM--DYFHVNANYIVWKTNHFTIPKEQYTIINRTA 86
+ P+ VV SN T C+ K + + I I + +
Sbjct 248 TNVFPQDKVVLAGSNMTICCISTTKVLSGQIGNTFRPLIHLYGETVAINILNIPVSENSG 307
Query 87 SSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEW 146
S+V F+ + +VYG + +G PP+ P+ LSC ++ K++ C W
Sbjct 308 SNVIFSTV------------------DDVYGTVVFAGYPPDVPQKLSCETHDLKEIICSW 349
Query 147 DGGRETHL----ETNFTLKSEWAT-----HKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
+ GR T L T +TL + H+F + + T ++
Sbjct 350 NPGRITGLVGPRNTEYTLFESISGKSAVFHRFEELANETYWLTLKMAPDQEIH----NFT 405
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY 257
+ A N LG+ S I + +V + P +L V + S+++ L+W P + I L
Sbjct 406 LTARNPLGQTES-AIVINATERVALHVPISLKVKDVN--STVVTLSWYLPGNFTKINLVC 462
Query 258 NIQ-YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
I+ + + + V L P+T Y FR+RC E WS WS E
Sbjct 463 QIEICKANSKKEVRNVTMRGAEDSTYHVAVDKLNPYTIYTFRVRCSSETF-WKWSKWSNE 521
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--RWK 374
+T E PSK P W + + + + + WK LP EANGKIL Y V+ +
Sbjct 522 KRYLTTEATPSKGPDTWRE----WSSDGKNLIIYWKPLPINEANGKILSYNVSCSSSEET 577
Query 375 SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA---AVLTIPACDFQATHPVMDLK 431
L K + + + Y+ ++ RN G S A + IP D + +
Sbjct 578 QSLSEILDPQHKAEIKVNKNDYIISVVARNSAGSSPPSKIASMEIPNDD------ITVEQ 631
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN-LAESK 490
A N +++ W Y+++WC S PC+ DW + T + +
Sbjct 632 AVGIGNRIFLSWQHNPNMTCDYVIKWCNSSWSEPCLLDWIKVPSNSTGTVIESDQFQPGV 691
Query 491 CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
Y + G S Y+++ P P + + +++WD +PV+ GF
Sbjct 692 RYNFYLYGCTNQGYQLLRSTIGYIEELAPIVAPNFTVEDTSADSILVKWDDIPVEELRGF 751
Query 551 IRNYTIFY----------RTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYT 596
+R Y ++ R++ + + + + D S ++ L T Y + + AYT
Sbjct 752 LRGYLFYFQKGERDTPKTRSLETSHSDIKLKNITDISQKTLRIADLQGKTSYHLVLRAYT 811
Query 597 DEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVP 656
G T + + G I AI++PV +A ++ + +L C+ KR+ IK+ +P++P
Sbjct 812 HGGLGPEKSMFVVTKENSVGLIIAILIPVAVAVIVGVVTSIL-CYRKREWIKETFYPDIP 870
Query 657 DPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKK 716
+P Q+ N +M T V +E+ P ED +
Sbjct 871 NPENCKALQFQKSVCEGSNALKTLEM---NPCTPNHVEVLESRSIPPKIEDTE--ITSPV 925
Query 717 EKINTEGHSSGIGGSSCMSSSRPSISSSDENESS--QNTSSTVQYSTVVHSGYRHQVPSV 774
+ E + + +S P I N ++ +S V Y V S Y+ Q +
Sbjct 926 SERPGESSETDPENQAAVSYCPPIIEEEITNPAADEAGGASQVVYIDV-QSMYQPQAKAE 984
Query 775 QVFSRSESTQPLLDSEERP----------EDLQLVDHVDGGDGILPRQQYFKQNCSQHES 824
+ T P++ + +P ED D D G P+ N +S
Sbjct 985 DE----QDTDPVMVAGYKPQMRLPINPTAEDTTAEDEADKTAGYRPQANVNTWNLVSPDS 1040
>sp|P42703|LIFR_MOUSE Leukemia inhibitory factor receptor OS=Mus
musculus OX=10090 GN=Lifr PE=1 SV=1
Length=1092
Score = 472 bits (1214), Expect = 4e-149, Method: Composition-based stats.
Identities = 164/763 (21%), Positives = 293/763 (38%), Gaps = 72/763 (9%)
Query 29 GYISPESPVVQLHSNFTAVCVLKEKCM--DYFHVNANYIVWKTNHFTIPKEQYTIINRTA 86
+ P+ VV SN T C+ K + + I I + +
Sbjct 247 TNVFPQDKVVLAGSNMTICCMSPTKVLSGQIGNTLRPLIHLYGQTVAIHILNIPVSENSG 306
Query 87 SSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEW 146
+++ F + +VYG + +G PP+ P+ LSC ++ K++ C W
Sbjct 307 TNIIFI------------------TDDDVYGTVVFAGYPPDVPQKLSCETHDLKEIICSW 348
Query 147 DGGRETHL----ETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW---VE 199
+ GR T L T +TL + + + T+ T E+ +
Sbjct 349 NPGRITGLVGPRNTEYTLFESISGKSAV--FHRIEGLTNETYRLGVQMHPGQEIHNFTLT 406
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
N LG+ S + + +V P+ P +L V + S+++ +W P + I L I
Sbjct 407 GRNPLGQAQS-AVVINVTERVAPHDPTSLKVKDIN--STVVTFSWYLPGNFTKINLLCQI 463
Query 260 Q-YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+ + + V L P+T Y FR+RC + WS WS+E
Sbjct 464 EICKANSKKEVRNATIRGAEDSTYHVAVDKLNPYTAYTFRVRCSSKTF-WKWSRWSDEKR 522
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--RWKSH 376
+T E PSK P W + + + + + WK LP EANGKIL Y V+ +
Sbjct 523 HLTTEATPSKGPDTWRE----WSSDGKNLIVYWKPLPINEANGKILSYNVSCSLNEETQS 578
Query 377 LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA---AVLTIPACDFQATHPVMDLKAF 433
+ + + L+ + Y+ ++ RN G S A + IP D + +A
Sbjct 579 VLEIFDPQHRAEIQLSKNDYIISVVARNSAGSSPPSKIASMEIPNDD------ITVEQAV 632
Query 434 PKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN-LAESKCY 492
N +++ W Y+++WC S PC+ DW++ T + + Y
Sbjct 633 GLGNRIFLTWRHDPNMTCDYVIKWCNSSRSEPCLLDWRKVPSNSTETVIESDQFQPGVRY 692
Query 493 LITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
+ G SI Y+++ P P + + +++WD +PV+ GF+R
Sbjct 693 NFYLYGCTNQGYQLLRSIIGYVEELAPIVAPNFTVEDTSADSILVKWDDIPVEELRGFLR 752
Query 553 NYTIFY----------RTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
Y ++ R++ + + + + D S ++ L T Y + + AYT
Sbjct 753 GYLFYFQKGERDTPKTRSLEPHHSDIKLKNITDISQKTLRIADLQGKTSYHLVLRAYTHG 812
Query 599 GGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDP 658
G T + + G I AI++PV +A ++ + +L C+ KR+ IK+ +P++P+P
Sbjct 813 GLGPEKSMFVVTKENSVGLIIAILIPVAVAVIVGVVTSIL-CYRKREWIKETFYPDIPNP 871
Query 659 SKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEK 718
Q+ N +M T +V +E+ P ED + + +
Sbjct 872 ENCKALQFQKSVCEGSNALKTLEM---NPCTPNNVEVLESRSIVPKIEDTEIISPVAER- 927
Query 719 INTEGHSSGIGGSSCMSSSRPSISSSDENESSQ--NTSSTVQY 759
E +S P I N ++ +S V Y
Sbjct 928 -PGERSEVDPENHVVVSYCPPIIEEEITNPAADEVGGASQVVY 969
>sp|Q8NI17|IL31R_HUMAN Interleukin-31 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL31RA PE=1 SV=1
Length=732
Score = 445 bits (1143), Expect = 7e-143, Method: Composition-based stats.
Identities = 175/637 (27%), Positives = 289/637 (45%), Gaps = 33/637 (5%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA-THKFADCKAKRDTP---TS 181
P KP+N+SC+ K + C W G+ET T +T+K +A K +C T S
Sbjct 22 PAKPENISCVYYYRKNLTCTWSPGKETS-YTQYTVKRTYAFGEKHDNCTTNSSTSENRAS 80
Query 182 CTVDYSTVYFV-NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
C+ + N + VEAEN G + S + K PP V + ++
Sbjct 81 CSFFLPRITIPDNYTIEVEAENGDGVIKSHMTYWRLENIAKTEPPKIFRVKPVLGIKRMI 140
Query 241 KLTWTNPSIKSVII-LKYNIQYRTKDASTWSQIP-PEDTASTRSSFTVQDLKPFTEYVFR 298
++ W P + V LKY +++RT ++++W ++ ++ ++ + L+PFTEYV
Sbjct 141 QIEWIKPELAPVSSDLKYTLRFRTVNSTSWMEVNFAKNRKDKNQTYNLTGLQPFTEYVIA 200
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+RC ++ K +WSDWS+E G+T E+ P W + P+ G R V+L+WK
Sbjct 201 LRCAVKESK-FWSDWSQEKMGMTEEEAPC-GLELWRVLKPAEADGRRPVRLLWKKARGAP 258
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNAT--KLTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
K L Y + + T+N T +L ++L + + ++ N +GKS A L I
Sbjct 259 VLEKTLGYNIWYYPESNTNLTETMNTTNQQLELHLGGESFWVSMISYNSLGKSPVATLRI 318
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
PA ++ + ++A ++ L V+W + V +++EW D P W+
Sbjct 319 PAIQEKSFQCIEVMQACVAEDQLVVKWQSSALDVNTWMIEWFPDVDSEPTTLSWESVSQA 378
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAV 536
+ T + L CY I+V P+ D G P SI+AY K+ PS+GP + + +G
Sbjct 379 TNWTIQQDKLKPFWCYNISVYPMLHDKVGEPYSIQAYAKEGVPSEGPETKVENIGVKTVT 438
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
+ W ++P + G I NYTIFY+ G + V+SS +Y L SL T Y+V++ A T
Sbjct 439 ITWKEIPKSERKGIICNYTIFYQAEGGKGFSKTVNSSILQYGLESLKRKTSYIVQVMAST 498
Query 597 DEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVP 656
GG +G F T F+ EI I + L+ +L V + K + + WP VP
Sbjct 499 SAGGTNGTSINFKTLSFSVFEIILITSLIGGGLLILIILTVAYGLKKPNKLTHLCWPTVP 558
Query 657 DPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDL----KSLD 712
+P++S IA W +F K + + + ++ P D K +
Sbjct 559 NPAESSIATWHG-----DDFKDKLNLKESDDSVNTEDRILKPCS---TPSDKLVIDKLVV 610
Query 713 LFKK--EKINTE----GHSSGIGGS---SCMSSSRPS 740
F ++I T+ G + +GG RP
Sbjct 611 NFGNVLQEIFTDEARTGQENNLGGEKNGYVTCPFRPD 647
>sp|Q8K5B1|IL31R_MOUSE Interleukin-31 receptor subunit alpha OS=Mus
musculus OX=10090 GN=Il31ra PE=1 SV=3
Length=716
Score = 441 bits (1133), Expect = 2e-141, Method: Composition-based stats.
Identities = 187/696 (27%), Positives = 301/696 (43%), Gaps = 57/696 (8%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNF--TLKSEWATHKFAD--CKAKRDTPTS 181
P KP+N+SC+ + + C W +ET+ +T++ TL + ++D +A P S
Sbjct 21 PTKPENISCVFYFDRNLTCTWRPEKETN-DTSYIVTLTYSYGKSNYSDNATEASYSFPRS 79
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
C + V V+A+N GKV SD + + K PP LSV + + + +
Sbjct 80 CAMPPDIC-----SVEVQAQNGDGKVKSDITYWHLISIAKTEPPIILSV--NPICNRMFQ 132
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+ W L +++RT ++S W+++ E+ + + L+ FTEYV +R
Sbjct 133 IQWKPREKTRGFPLVCMLRFRTVNSSHWTEVNFENC---KQVCNLTGLQAFTEYVLALRF 189
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
D + YWS WS+E + +T E+ P W ++P+ G R V+L+WK
Sbjct 190 RFNDSR-YWSKWSKEETRVTMEEVP-HVLDLWRILEPADMNGDRKVRLLWKKARGAPVLE 247
Query 362 KILDYEVTLTRWKSHLQNYTVNAT--KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
K Y + S N T + + L + + ++T N +GKS A+L IP
Sbjct 248 KTFGYHIQYFAENSTNLTEINNITTQQYELLLMSQAHSVSVTSFNSLGKSQEAILRIPDV 307
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD-KAPCITDWQQEDGTVH 478
+ + +KA+ + +L V W + +V +I+EW + W+ +
Sbjct 308 HEKTFQYIKSMKAYIAEPLLVVNWQSSIPAVDTWIVEWLPEAAMSKFPALSWESVSQVTN 367
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
T + L CY I+V PV G P SI+AY K+ P KGP R + +G A +
Sbjct 368 WTIEQDKLKPFTCYNISVYPVLGHRVGEPYSIQAYAKEGTPLKGPETRVENIGLRTATIT 427
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
W ++P +NGFI NYT+FY+ G E + V+S + L SLT T Y V + A T
Sbjct 428 WKEIPKSARNGFINNYTVFYQAEGGKELSKTVNSHALQCDLESLTRRTSYTVWVMASTRA 487
Query 599 GGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDP 658
GG +G F T + EI + V LL ++ V F K + + P+VP+P
Sbjct 488 GGTNGVRINFKTLSISVFEIVLLTSLVGGGLLLLSIKTVTFGLRKPNRLTPLCCPDVPNP 547
Query 659 SKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDL--KSLDLFKK 716
++S +A W + K M GN D V ++ P P DL K + F+
Sbjct 548 AESSLATWL------GDGFKKSNMKETGNSGDTEDVVLKPC---PVPADLIDKLVVNFEN 598
Query 717 --EKINTE----GHSSGIGG---SSCMSSSRP---------------SISSSDENESSQN 752
E + TE G +S +GG S SRP ++S D + +
Sbjct 599 FLEVVLTEEAGKGQASILGGEANEYVTSPSRPDGPPGKSFKEPSVLTEVASEDSHSTCSR 658
Query 753 TSSTVQYSTVVHSGYRH-QVPSVQVFSRSESTQPLL 787
+ YS + Q P + ++ P L
Sbjct 659 MADEA-YSELARQPSSSCQSPGLSPPREDQAQNPYL 693
>sp|Q65Z14|OSMR_RAT Oncostatin-M-specific receptor subunit beta
OS=Rattus norvegicus OX=10116 GN=Osmr PE=2 SV=1
Length=962
Score = 415 bits (1066), Expect = 6e-129, Method: Composition-based stats.
Identities = 149/666 (22%), Positives = 261/666 (39%), Gaps = 65/666 (10%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
I PE +++ SN T ++ + ++V+ + I ++V
Sbjct 151 IFPEDRLLEEGSNVTICLMIGQN---LYNVSCKLQEEPIRGEQLDSHLSLI---KLNNVV 204
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
F + A NI C + + N +G + E+PKN SC + K + C W+ G
Sbjct 205 FLNNAGTNIN--CKAMNGTK---NTFGTVLFVSKVLEEPKNFSCETRDFKTLNCLWEPGI 259
Query 151 ETHLE------TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
+T L ++TL ++ + + T D + AEN L
Sbjct 260 DTTLSWHKQRSQHYTLYESFSGRR-EVSNHRNSHTWQITEDSQE----TYNFTLTAENNL 314
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK 264
K S I+F+ ++V P PH++++ + +TW PS L ++ + +
Sbjct 315 RK-RSVSISFNLTHRVHPKAPHDVTLKTVGATKA--HMTWKVPSRGDY-TLLCQVELQCE 370
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
T++ + DL+P TEY +RC + WSDW ++ T E
Sbjct 371 GEVIHEHNVSVHTSAN---YLFSDLEPDTEYKACVRCASANHFWKWSDWMQKK-FRTPEA 426
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK--SHLQNYTV 382
PS+A W D G V L WK L +ANGKI+ Y + + + + Y+V
Sbjct 427 APSEALDVWR--DVRTENGRHVVTLFWKPLLKSQANGKIISYNIVVENEANPTESEQYSV 484
Query 383 NATKLTVNLTND--RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW 440
A L NL+ D Y ++ N G S +++ + + +K N
Sbjct 485 RAPALGTNLSLDLHPYKIHISANNSAGASPESLVVLSSHSGHEEVHEKTIKGI--KNGFN 542
Query 441 VEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN-LAESKCYLITVTPV 499
+ W Y+++WC S C W+ + T + + Y +
Sbjct 543 ISWEPVSGDAIGYVVDWCAHSQTQRCDLQWKNVGPNITSTIITSDAFEPGVRYNFRIFER 602
Query 500 Y-ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
+ E + Y ++ PS P V + N L+W D Q+GFI+ Y ++
Sbjct 603 SVEENVRLVEKQRGYTQELAPSVNPGVTIHNLTPNSFSLKWQDYASDFQSGFIKGYLVYL 662
Query 559 ------------RTIIGNETAV---NVDSSHT-EYTLSSLTSDTLYMVRMAAYTDEGGKD 602
RT++ +++ + +VD T T+ +L ++LY + YT G
Sbjct 663 KSKELQCNPNWERTVLSDKSVLCKYDVDDPETKTLTVENLRPESLYEFLVTPYTSAG--Q 720
Query 603 GPEFT---FTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPS 659
GP T TTP + I++P+ L L ++ C+ K +K+ +P++P+P
Sbjct 721 GPNETYTKVTTPDVRSHMLLQIILPMTLGVFL----SIIVCYWKSQWVKEKCYPDIPNPY 776
Query 660 KSHIAQ 665
KS I
Sbjct 777 KSSILS 782
>sp|Q99650|OSMR_HUMAN Oncostatin-M-specific receptor subunit beta
OS=Homo sapiens OX=9606 GN=OSMR PE=1 SV=1
Length=979
Score = 410 bits (1052), Expect = 8e-127, Method: Composition-based stats.
Identities = 166/774 (21%), Positives = 284/774 (37%), Gaps = 69/774 (9%)
Query 30 YISPESPVVQLHSNFTAVCVLKE-KCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASS 88
++ P+ +V+ +N T V + + ++ I + + +S
Sbjct 150 FVFPKDKLVEEGTNVTICYVSRNIQNNVSCYLEGKQIH----GEQLDPH---VTAFNLNS 202
Query 89 VTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG 148
V F NI C + G + + + GI + E+PK+ SC + K + C WD
Sbjct 203 VPFIRNKGTNI--YC-EASQGNVSEGMKGIVLFVSKVLEEPKDFSCETEDFKTLHCTWDP 259
Query 149 GRETHL------ETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN 202
G +T L ++TL ++ K C K T D + AEN
Sbjct 260 GTDTALGWSKQPSQSYTLFESFSGEK-KLCTHKNWCNWQITQDSQE----TYNFTLIAEN 314
Query 203 ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYR 262
L K S +I F+ ++V P +++ N ++I +TW SI++ I+
Sbjct 315 YLRK-RSVNILFNLTHRVYLMNPFSVNFENVNATNAI--MTWKVHSIRNNFTYLCQIELH 371
Query 263 TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ + + + + +L+P TEY+ R+RC WS+WS + + T
Sbjct 372 GEGKMMQYNVSIK----VNGEYFLSELEPATEYMARVRCADASHFWKWSEWSGQ-NFTTL 426
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT----RWKSHLQ 378
E PS+AP W + S G TV L WK L ANGKIL Y V + S L
Sbjct 427 EAAPSEAPDVWRIV--SLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELH 484
Query 379 NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
+ A + L Y + N VG S A+V+ I A V + + +
Sbjct 485 SIPAPANSTKLILDRCSYQICVIANNSVGASPASVIVISAD--PENKEVEEERIAGTEGG 542
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN-LAESKCYLITVT 497
+ W V Y+++WC + W+ T + + Y +
Sbjct 543 FSLSWKPQPGDVIGYVVDWCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIY 602
Query 498 PVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
+ E Y ++ PS P V + + L W + Q GFI+ Y +
Sbjct 603 GLSTKRIACLLEKKTGYSQELAPSDNPHVLVDTLTSHSFTLSWKDYSTESQPGFIQGYHV 662
Query 557 FYRTI--------------IGNETAVNV--DSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
+ ++ G+E + + +L ++ Y + +T G
Sbjct 663 YLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAG- 721
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
+GP TF T E ++++ + L + LL ++ C+ K IK+ +P++PDP K
Sbjct 722 -EGPSATF-TKVTTPDEHSSMLIHILLPMVFCVLLIMVMCYLKSQWIKETCYPDIPDPYK 779
Query 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
S I + N + SD + VV K F KSL + K N
Sbjct 780 SSILS---LIKFKENPHLIIMNVSDCIPDAIEVVSKPEGTKIQFLGTRKSLTETELTKPN 836
Query 721 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSV 774
+ + S P I + + + S + H + PS+
Sbjct 837 ---YLYLLPTEKNHSGPGPCICFENLTYNQAASDS----GSCGHVPVSPKAPSM 883
>sp|O70458|OSMR_MOUSE Oncostatin-M-specific receptor subunit beta
OS=Mus musculus OX=10090 GN=Osmr PE=1 SV=1
Length=971
Score = 409 bits (1051), Expect = 1e-126, Method: Composition-based stats.
Identities = 149/670 (22%), Positives = 264/670 (39%), Gaps = 69/670 (10%)
Query 29 GYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASS 88
I P+ V++ SN T + + ++V+ I EQ ++ S
Sbjct 148 SLIFPKDKVLEEGSNVTICLMYGQNV---YNVSCK-----LQDEPIHGEQ---LDSHVSL 196
Query 89 VTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG 148
+ ++ L+ T + + ++G + E+PKN+SC + K + C W+
Sbjct 197 LKLNNVVFLSDTGTNINCQATKGPKRIFGTVLFVSKVLEEPKNVSCETRDFKTLDCSWEP 256
Query 149 GRETHLE------TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN 202
G +T L N+TL E + + + T + + AEN
Sbjct 257 GVDTTLTWRKQRFQNYTL-CESFSKRCEVSNYRNSYTWQITEGSQEM----YNFTLTAEN 311
Query 203 ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYR 262
L K S +INF+ ++V P P ++++ + +TW S + L ++ +
Sbjct 312 QLRK-RSVNINFNLTHRVHPKAPQDVTLKIIGATKA--NMTWKVHSHGNNYTLLCQVKLQ 368
Query 263 TKDASTWSQIPPEDTASTRSS--FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
+ ++ E S S + DL P T+Y +RC + WSDW+++
Sbjct 369 ------YGEVIHEHNVSVHMSANYLFSDLDPDTKYKAFVRCASANHFWKWSDWTQKE-FS 421
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK--SHLQ 378
T E PS+A W ++ G R V L WK L +ANGKI+ Y + + + +
Sbjct 422 TPETAPSQALDVWRQV--WSENGRRIVTLFWKPLLKSQANGKIISYNIVVENEAKPTESE 479
Query 379 NYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
+Y V A L+ NL+ D Y +T N +G S +++ + +K
Sbjct 480 HYCVWAPALSTNLSLDLQPYKIRITTNNSMGASPESLMVLSNDSGHEEVKEKTIKGI--K 537
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT-VHRTYLRGNLAESKCYLIT 495
+ + W Y+++WC S C W+ T + Y
Sbjct 538 DAFNISWEPVSGDTMGYVVDWCAHSQDQRCDLQWKNLGPNTTSTTITSDDFKPGVRYNFR 597
Query 496 VTPVYADGPG-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
+ + E + Y ++ P P V N VL W D Q GFI+ Y
Sbjct 598 IFERSVEHKARLVEKQRGYTQELAPLVNPKVEIPYSTPNSFVLRWPDYDSDFQAGFIKGY 657
Query 555 TIFY------------RTIIGNETAV---NVDSSHT-EYTLSSLTSDTLYMVRMAAYTDE 598
++ RT++ + + + +++ S T T+ +L ++LY + YT
Sbjct 658 LVYVKSKEMQCNQPWERTLLPDNSVLCKYDINGSETKTLTVENLQPESLYEFFVTPYTSA 717
Query 599 GGKDGPEFTF---TTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNV 655
G GP TF TTP + I++P+ L LL ++ C+ K +K+ +P++
Sbjct 718 G--PGPNETFTKVTTPDARSHMLLQIILPMTLCVLL----SIIVCYWKSQWVKEKCYPDI 771
Query 656 PDPSKSHIAQ 665
P+P KS I
Sbjct 772 PNPYKSSILS 781
>sp|Q62959|LEPR_RAT Leptin receptor OS=Rattus norvegicus OX=10116
GN=Lepr PE=1 SV=1
Length=1162
Score = 368 bits (945), Expect = 7e-110, Method: Composition-based stats.
Identities = 115/512 (22%), Positives = 194/512 (38%), Gaps = 45/512 (9%)
Query 32 SPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHF-TIPKEQYTIINRTASSVT 90
P + + SN + C+ K + +++ IVW N IP+ QY ++ S VT
Sbjct 334 FPPKILTSVGSNASFCCIYKNENQT---ISSKQIVWWMNLAEKIPETQYNTVSDHISKVT 390
Query 91 FTDIAS--------LNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKM 142
F+++ + + CN +Y I + + E L+ KM
Sbjct 391 FSNLKATRPRGKFTYDAVYCCNEQACHHRYAELYVIDVNINISCETDGYLT-------KM 443
Query 143 RCEWDGGRETHL-----ETNFTLKSEWA--------THKFADCKAKRDTPTSCTVDYSTV 189
C W L + + +S + T + +C + D C
Sbjct 444 TCRWSPSTIQSLVGSTVQLRYHRRSLYCPDNPSIRPTSELKNCVLQTDGFYECVFQ-PIF 502
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+W+ ++LG + S P VKP PP N+ + + +LK++W P
Sbjct 503 LLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVKAEIT-INTGLLKVSWEKPVF 561
Query 250 KSVIILKYNIQYRTKDAS-TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
L++ I+Y W D S +S V DL YV ++RC + DG G
Sbjct 562 PEN-NLQFQIRYGLNGKEIQWKTHEVFDAKSKSASLPVSDL--CAVYVVQVRCRRLDGLG 618
Query 309 YWSDWSEEASGITYE-DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
YWS+WS A + + P + P FW +D T+ R V L+WK L ++ + Y
Sbjct 619 YWSNWSSPAYTLVMDVKVPMRGPEFWRIMDGDITKKERNVTLLWKPLMKNDSLCSVRRYV 678
Query 368 VTLTRWK-SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
V N T LT + T+ N +G S + +
Sbjct 679 VKHRTAHNGTWSQDVGNQTNLTFLWAESAHTVTVLAINSIGASLVNFNLTFSWPMSKVNA 738
Query 427 VMDLKAFP-KDNMLWVEWTTPRES--VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
V L A+P + + + WT + ++EW L+D W + V++ Y+
Sbjct 739 VQSLSAYPLSSSCVILSWTLSPNDYSLLYLVIEWKNLNDDDG--MKWLRIPSNVNKYYIH 796
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
N + Y ++ PV+ +G G P+ I + K
Sbjct 797 DNFIPIEKYQFSLYPVFMEGVGKPKIINGFTK 828
Score = 79.5 bits (194), Expect = 1e-13, Method: Composition-based stats.
Identities = 68/488 (14%), Positives = 148/488 (30%), Gaps = 70/488 (14%)
Query 160 LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-TSDHINFDPVY 218
LK + T + + + C V + + G S ++ P+
Sbjct 177 LKDSFQTVQCNCSVRECE----CHVPVPRAKVNYALLMYLEITSAGVSFQSPLMSLQPML 232
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
VKP+PP L + +++ + LK++W + + +QY+ K + +
Sbjct 233 VVKPDPPLGLRMEVTDDGN--LKISWDSQTKAPFP-----LQYQVKYLENSTIVREAAEI 285
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+ +S V + P + Y ++R + DG G WSDWS T +D P +
Sbjct 286 VSDTSLLVDSVLPGSSYEVQVRSKRLDGSGVWSDWSLPQLFTT-QDVMYFPPKILTSVGS 344
Query 339 SHT------QGYRTV----QLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLT 388
+ + +T+ + W L Y + ++ T
Sbjct 345 NASFCCIYKNENQTISSKQIVWWMNLAEKIPE---TQYN--------TVSDHISKVTFSN 393
Query 389 VNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK---AFPKD---NMLWVE 442
+ T R T A V+D+ + D +
Sbjct 394 LKATRPRGKFTYDAV-------YCCNEQACHHRYAELYVIDVNINISCETDGYLTKMTCR 446
Query 443 WTTPR-ESVKKYILE--------WCVLSDKAPCITDWQQEDGTVHRTY--LRGNLAESKC 491
W+ +S+ ++ +C + ++ + Y + +
Sbjct 447 WSPSTIQSLVGSTVQLRYHRRSLYCPDNPSIRPTSELKNCVLQTDGFYECVFQPIFLLSG 506
Query 492 YLITVTPVYADGPGSPESIKAYLKQAP--PSKGPTVRTKKVGKNEAV-LEWDQLPVDVQN 548
Y + + + L + P V+ + + + W++ N
Sbjct 507 YTMWIR-INHSLGSLDSPPTCVLPDSVVKPLPPSNVKAEITINTGLLKVSWEKPVFPENN 565
Query 549 GFIRNYTIFYRTIIGN---ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ I Y +T D+ +L +Y+V++ +G G
Sbjct 566 ---LQFQIRYGLNGKEIQWKTHEVFDAKSKSASLPVSDLCAVYVVQVRCRRLDGL--GYW 620
Query 606 FTFTTPKF 613
+++P +
Sbjct 621 SNWSSPAY 628
Score = 66.8 bits (161), Expect = 8e-10, Method: Composition-based stats.
Identities = 124/835 (15%), Positives = 258/835 (31%), Gaps = 139/835 (17%)
Query 4 LQTWLVQALFIFLTTESTGEL-------LDPCGYISPESPVVQLHSNFTAVCVLKEKCMD 56
+ + AL ++L S G L P + P+ P+ V + +
Sbjct 200 PRAKVNYALLMYLEITSAGVSFQSPLMSLQPMLVVKPDPPLGLRME------VTDDGNLK 253
Query 57 YFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVY 116
+ + + E TI+ R A+ + ++ L + + +
Sbjct 254 ISWDSQTKAPFPLQYQVKYLENSTIV-REAAEIVSDTSLLVDSVLPGSSYEVQVRSKRLD 312
Query 117 GITIISGLP-PE----------KPKNLS--------CIVNEGKKMR------CEWDGGRE 151
G + S P+ PK L+ C + + + W E
Sbjct 313 GSGVWSDWSLPQLFTTQDVMYFPPKILTSVGSNASFCCIYKNENQTISSKQIVWWMNLAE 372
Query 152 THLETNFTLKSEWATH-KFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD 210
ET + S+ + F++ KA R Y +A
Sbjct 373 KIPETQYNTVSDHISKVTFSNLKATR-------PRGKFTYDAVYCCNEQA--------CH 417
Query 211 HINFDPVYKVKPNPPHNLSVI-NSEELSSILKLTWTNPSIKSVIILKYNIQY------RT 263
H + N+++ ++ + + W+ +I+S++ ++Y
Sbjct 418 HRYAELYVID-----VNINISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCP 472
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKP---FTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
+ S ++ F +P + Y IR G S S +
Sbjct 473 DNPSIRPTSELKNCVLQTDGFYECVFQPIFLLSGYTMWIRINHSLG----SLDSPPTCVL 528
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT------RWK 374
+ P K + + G +++ W+ E N L +++ +WK
Sbjct 529 -PDSVVKPLPPSNVKAEITINTGL--LKVSWEKPVFPENN---LQFQIRYGLNGKEIQWK 582
Query 375 SHLQ-NYTVNATKLTVNLTNDRYLATLTVRNLVG------KSDAAVLTIPACDFQATHP- 426
+H + + L V+ Y+ + R L G S A + P
Sbjct 583 THEVFDAKSKSASLPVSDLCAVYVVQVRCRRLDGLGYWSNWSSPAYTLVMDVKVPMRGPE 642
Query 427 ---VMDLKAFPKDNMLWVEWTTPRE-----SVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
+MD K+ + + W + SV++Y+++ + W Q+ G
Sbjct 643 FWRIMDGDITKKERNVTLLWKPLMKNDSLCSVRRYVVKHRTAHNGT-----WSQDVGNQT 697
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL-KQAPPSKGPTVRTKKVGKNEAVL 537
L + +TV + + G + + + ++ + + +L
Sbjct 698 N---LTFLWAESAHTVTVLAINSIGASLVNFNLTFSWPMSKVNAVQSLSAYPLSSSCVIL 754
Query 538 EWDQLPVDVQNGFIRNYTIFY---RTIIGNETA----VNVDSSHTEYTL-SSLTSDTLYM 589
W P D Y++ Y N+ + + S+ +Y + + Y
Sbjct 755 SWTLSPND--------YSLLYLVIEWKNLNDDDGMKWLRIPSNVNKYYIHDNFIPIEKYQ 806
Query 590 VRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIK 648
+ EG GK FT A+ + +A + + + + +L + +K
Sbjct 807 FSLYPVFMEGVGKPKIINGFTKDDIAKQQNDAGLYVIVPIIISSCVLLLGTLLISHQRMK 866
Query 649 KHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDL 708
K W +VP+P AQ P + + F + + + +P E++
Sbjct 867 KLFWDDVPNPKNCSWAQGLNFQKPETFEHLFTKHAESVIFGPLLL------EPEPVSEEI 920
Query 709 KSLDLFKK--EKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYST 761
+K E + S + + S+R SI SD+ S+ + + T
Sbjct 921 SVDTAWKNKDEMVPAAMVSLLL---TTPDSTRGSICISDQCNSANFSGAQSTQGT 972
>sp|P48357|LEPR_HUMAN Leptin receptor OS=Homo sapiens OX=9606
GN=LEPR PE=1 SV=2
Length=1165
Score = 366 bits (940), Expect = 4e-109, Method: Composition-based stats.
Identities = 116/568 (20%), Positives = 207/568 (36%), Gaps = 63/568 (11%)
Query 32 SPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHF-TIPKEQYTIINRTASSVT 90
P + + SN + C+ K++ + IVW N IP+ QY +++ S VT
Sbjct 336 FPPKILTSVGSNVSFHCIYKKENKIVP---SKEIVWWMNLAEKIPQSQYDVVSDHVSKVT 392
Query 91 FTDIAS--------LNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKM 142
F ++ + CN +Y I + + E L+ KM
Sbjct 393 FFNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLT-------KM 445
Query 143 RCEWDGGR-----ETHLETNFTLKSEWAT--------HKFADCKAKRDTPTSCTVDYSTV 189
C W E+ L+ + S + + + DC + D C
Sbjct 446 TCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQ-PIF 504
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+W+ ++LG + S P VKP PP ++ + + +LK++W P
Sbjct 505 LLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIG-LLKISWEKPVF 563
Query 250 KSVIILKYNIQYRTKDAS-TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
L++ I+Y W D S S V DL Y ++RC + DG G
Sbjct 564 PEN-NLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDL--CAVYAVQVRCKRLDGLG 620
Query 309 YWSDWSEEASGITYE-DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
YWS+WS A + + P + P FW I+ + + V L+WK L ++ + Y
Sbjct 621 YWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYV 680
Query 368 VT-LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
+ T N TK T T + T+ N +G S A + +
Sbjct 681 INHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSIGASVANFNLTFSWPMSKVNI 740
Query 427 VMDLKAFP-KDNMLWVEWTTPRES--VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
V L A+P + + V W + +I+EW L++ W + +V + Y+
Sbjct 741 VQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNEDGE--IKWLRISSSVKKYYIH 798
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLK----QAPPSKGPTVRTKKVGKNEAV--- 536
+ + Y ++ P++ +G G P+ I ++ + + G V + + +
Sbjct 799 DHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDAGLYVIVPVIISSSILLLG 858
Query 537 -----------LEWDQLPVDVQNGFIRN 553
L W+ +P + +
Sbjct 859 TLLISHQRMKKLFWEDVPNPKNCSWAQG 886
Score = 84.5 bits (207), Expect = 3e-15, Method: Composition-based stats.
Identities = 42/205 (20%), Positives = 75/205 (37%), Gaps = 26/205 (13%)
Query 208 TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS 267
S ++ P+ VKP+PP L + +++ + LK++W++P + L+Y ++Y +
Sbjct 223 QSPLMSVQPINMVKPDPPLGLHMEITDDGN--LKISWSSPPLVP-FPLQYQVKYSENSTT 279
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED--- 324
I D + +S V + P + Y ++R + DG G WSDWS T +
Sbjct 280 V---IREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYF 336
Query 325 RPSKAPSFWYKIDPSHTQGYRTV------QLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
P S + + W L Y+V +
Sbjct 337 PPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEKIPQS---QYDV--------VS 385
Query 379 NYTVNATKLTVNLTNDRYLATLTVR 403
++ T +N T R T
Sbjct 386 DHVSKVTFFNLNETKPRGKFTYDAV 410
Score = 63.0 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 74/535 (14%), Positives = 166/535 (31%), Gaps = 62/535 (12%)
Query 329 APSFWYKIDPSHTQGYRTVQL-----VWKTLPPFEANGKILDYEVTLTRWKSHLQ----- 378
S + PS + T+ + W+ E N L +++ +Q
Sbjct 531 PDSVVKPLPPSSVKAEITINIGLLKISWEKPVFPENN---LQFQIRYGLSGKEVQWKMYE 587
Query 379 NYTVNATKLTVNLTNDRYLATLTVRNL--------VGKSDAAVLTIPACDFQATHP---- 426
Y + +++ + + + + VR S+ A + P
Sbjct 588 VYDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWR 647
Query 427 VMDLKAFPKDNMLWVEWTTPRE-----SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
+++ K+ + + W + SV++Y++ + C W ++ G +
Sbjct 648 IINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVI-----NHHTSCNGTWSEDVGNHTKF- 701
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYL-KQAPPSKGPTVRTKKVGKNEAVLEWD 540
L + + +TV + + G + + + ++ + + ++ W
Sbjct 702 --TFLWTEQAHTVTVLAINSIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWI 759
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSS---HTEYTLSSLTSDTLYMVRMAAYTD 597
P D + + I ++ + + + S Y Y +
Sbjct 760 LSPSDY---KLMYFIIEWKNLNEDGEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFM 816
Query 598 EG-GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVP 656
EG GK +FT + + +A + + + +++L + +KK W +VP
Sbjct 817 EGVGKPKIINSFTQDDIEKHQSDAGLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVP 876
Query 657 DPSKSHIAQWSPHTPP---RHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDL 713
+P AQ P H F + G I + K ++
Sbjct 877 NPKNCSWAQGLNFQKPETFEHLFIKHTASVTCGPLLLEPET-ISEDISVDTSWKNKD-EM 934
Query 714 FKKEKINTEGHSSGIGGSSCMSSSRPSISSSDEN------ESSQNTSSTVQYSTVVHSGY 767
++ + GS C+S S++ S+ E V+Y+T++ S
Sbjct 935 MPTTVVSLLSTTDLEKGSVCISDQFNSVNFSEAEGTEVTYEDESQRQPFVKYATLI-SNS 993
Query 768 RHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQH 822
+ + + S S+ P L D + Q +F +
Sbjct 994 KPSETGEEQGLINSSVTKCFSSKNSP----LKDSFSNSSWEIEAQAFFILSDQHP 1044
Score = 39.8 bits (91), Expect = 0.13, Method: Composition-based stats.
Identities = 21/138 (15%), Positives = 49/138 (36%), Gaps = 6/138 (4%)
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM-LWVEWTTPRESV 450
ND L L + + + ++++ + P + L D+ L + W++P +
Sbjct 205 LNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGNLKISWSSPP--L 262
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG---SP 507
+ L++ V + + + + L ++ Y + V DGPG
Sbjct 263 VPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDW 322
Query 508 ESIKAYLKQAPPSKGPTV 525
+ + + Q P +
Sbjct 323 STPRVFTTQDVIYFPPKI 340
>sp|P48356|LEPR_MOUSE Leptin receptor OS=Mus musculus OX=10090
GN=Lepr PE=1 SV=1
Length=1162
Score = 366 bits (938), Expect = 6e-109, Method: Composition-based stats.
Identities = 120/532 (23%), Positives = 203/532 (38%), Gaps = 45/532 (8%)
Query 14 IFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHF- 72
++ S P + + SN + C+ K + +++ IVW N
Sbjct 316 VWSDWSSPQVFTTQDVVYFPPKILTSVGSNASFHCIYKNENQI---ISSKQIVWWRNLAE 372
Query 73 TIPKEQYTIINRTASSVTFTDIAS--------LNIQLTCNILTFGQLEQNVYGITIISGL 124
IP+ QY+I++ S VTF+++ + + CN +Y I + +
Sbjct 373 KIPEIQYSIVSDRVSKVTFSNLKATRPRGKFTYDAVYCCNEQACHHRYAELYVIDVNINI 432
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHL-----ETNFTLKSEWA--------THKFAD 171
E L+ KM C W L + + +S + T + +
Sbjct 433 SCETDGYLT-------KMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKN 485
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVI 231
C +RD C +W+ ++LG + S P VKP PP N+
Sbjct 486 CVLQRDGFYECVFQ-PIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVKAE 544
Query 232 NSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS-TWSQIPPEDTASTRSSFTVQDLK 290
+ + +LK++W P L++ I+Y W D S +S V DL
Sbjct 545 IT-VNTGLLKVSWEKPVFPEN-NLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDL- 601
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE-DRPSKAPSFWYKIDPSHTQGYRTVQL 349
YV ++RC + DG GYWS+WS A + + P + P FW K+D T+ R V L
Sbjct 602 -CAVYVVQVRCRRLDGLGYWSNWSSPAYTLVMDVKVPMRGPEFWRKMDGDVTKKERNVTL 660
Query 350 VWKTLPPFEANGKILDYEVTLTRWK-SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK 408
+WK L ++ + Y V N T LT T + T+ N +G
Sbjct 661 LWKPLTKNDSLCSVRRYVVKHRTAHNGTWSEDVGNRTNLTFLWTEPAHTVTVLAVNSLGA 720
Query 409 SDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRES--VKKYILEWCVLSDKAP 465
S + V L A+P + + + WT + + ++EW +L++
Sbjct 721 SLVNFNLTFSWPMSKVSAVESLSAYPLSSSCVILSWTLSPDDYSLLYLVIEWKILNEDDG 780
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
W + V + Y+ N + Y ++ PV+ +G G P+ I + K A
Sbjct 781 --MKWLRIPSNVKKFYIHDNFIPIEKYQFSLYPVFMEGVGKPKIINGFTKDA 830
Score = 78.7 bits (192), Expect = 2e-13, Method: Composition-based stats.
Identities = 35/163 (21%), Positives = 66/163 (40%), Gaps = 12/163 (7%)
Query 160 LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-TSDHINFDPVY 218
LK + T + +C + C V + + G S ++ P+
Sbjct 177 LKDSFQTVQC-NCSLR---GCECHVPVPRAKLNYALLMYLEITSAGVSFQSPLMSLQPML 232
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
VKP+PP L + +++ + LK++W + ++ +QY+ K + +
Sbjct 233 VVKPDPPLGLHMEVTDDGN--LKISWDSQTMAPFP-----LQYQVKYLENSTIVREAAEI 285
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+ +S V + P + Y ++R + DG G WSDWS T
Sbjct 286 VSATSLLVDSVLPGSSYEVQVRSKRLDGSGVWSDWSSPQVFTT 328
Score = 70.3 bits (170), Expect = 7e-11, Method: Composition-based stats.
Identities = 143/939 (15%), Positives = 278/939 (30%), Gaps = 172/939 (18%)
Query 4 LQTWLVQALFIFLTTESTGEL-------LDPCGYISPESPVVQLHSNFTAVCVLKEKCMD 56
+ L AL ++L S G L P + P+ P+ LH T + +
Sbjct 200 PRAKLNYALLMYLEITSAGVSFQSPLMSLQPMLVVKPDPPL-GLHMEVT-----DDGNLK 253
Query 57 YFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVY 116
+ + + E TI+ R A+ + ++ L + + +
Sbjct 254 ISWDSQTMAPFPLQYQVKYLENSTIV-REAAEIVSATSLLVDSVLPGSSYEVQVRSKRLD 312
Query 117 GITIISG-----------LPPEKPKNLS---------CIVNEGKKMR-----CEWDGGRE 151
G + S + PK L+ CI ++ W E
Sbjct 313 GSGVWSDWSSPQVFTTQDVVYFPPKILTSVGSNASFHCIYKNENQIISSKQIVWWRNLAE 372
Query 152 THLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDH 211
E +++ K K P Y +A H
Sbjct 373 KIPEIQYSI-VSDRVSKVTFSNLKATRP-----RGKFTYDAVYCCNEQA--------CHH 418
Query 212 INFDPVYKVKPNPPHNLSVI-NSEELSSILKLTWTNPSIKSVIILKYNIQY------RTK 264
+ N+++ ++ + + W+ +I+S++ ++Y
Sbjct 419 RYAELYVID-----VNINISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPD 473
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKP---FTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
S P++ R F +P + Y IR G S S +
Sbjct 474 SPSIHPTSEPKNCVLQRDGFYECVFQPIFLLSGYTMWIRINHSLG----SLDSPPTCVL- 528
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT------RWKS 375
+ P K + + G +++ W+ E N L +++ +WK+
Sbjct 529 PDSVVKPLPPSNVKAEITVNTGL--LKVSWEKPVFPENN---LQFQIRYGLSGKEIQWKT 583
Query 376 HLQ-NYTVNATKLTVNLTNDRYLATLTVRNLVG------KSDAAVLTIPACDFQATHPV- 427
H + + L V+ Y+ + R L G S A + P
Sbjct 584 HEVFDAKSKSASLLVSDLCAVYVVQVRCRRLDGLGYWSNWSSPAYTLVMDVKVPMRGPEF 643
Query 428 ---MDLKAFPKDNMLWVEWTTPRE-----SVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
MD K+ + + W + SV++Y+++ + W ++ G
Sbjct 644 WRKMDGDVTKKERNVTLLWKPLTKNDSLCSVRRYVVKHRTAHNGT-----WSEDVGNRTN 698
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL-KQAPPSKGPTVRTKKVGKNEAVLE 538
L + +TV V + G + + S ++ + + +L
Sbjct 699 ---LTFLWTEPAHTVTVLAVNSLGASLVNFNLTFSWPMSKVSAVESLSAYPLSSSCVILS 755
Query 539 WDQLPVD-VQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
W P D + + I + + Y + Y +
Sbjct 756 WTLSPDDYSLLYLVIEWKILNEDDGMKWLRIPSNVKKF-YIHDNFIPIEKYQFSLYPVFM 814
Query 598 EGGK-----DG-PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHI 651
EG +G + + G + + + LL L + +KK
Sbjct 815 EGVGKPKIINGFTKDAIDKQQNDAGLYVIVPIIISSCVLLLGTLLISH-----QRMKKLF 869
Query 652 WPNVPDPSKSHIAQ--------WSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIE---AND 700
W +VP+P AQ H +H + + ++ N
Sbjct 870 WDDVPNPKNCSWAQGLNFQKPETFEHLFTKHAESVIFGPLLLEPEPISEEISVDTAWKNK 929
Query 701 KKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPS-ISSSDENESSQNTSSTVQY 759
+ P + SL L + ++ S S+ S S+ + ++ DE + + V+Y
Sbjct 930 DEMVPAAMVSLLLTTPDPESSSICISDQCNSANFSGSQSTQVTCEDECQRQPS----VKY 985
Query 760 STVV---------------HSG-----YRHQVPSVQVFSRS----ESTQPLLDSEERPED 795
+T+V HS + P Q FS S E+ L S+++P
Sbjct 986 ATLVSNDKLVETDEEQGFIHSPVSNCISSNHSPLRQSFSSSSWETEAQTFFLLSDQQPTM 1045
Query 796 LQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERS 834
+ G D +L + S P+ +H E+S
Sbjct 1046 ISPQLSFSGLDELLELE----------GSFPEENHREKS 1074
>sp|Q9MYL0|LEPR_MACMU Leptin receptor OS=Macaca mulatta OX=9544
GN=LEPR PE=2 SV=2
Length=1163
Score = 361 bits (927), Expect = 3e-107, Method: Composition-based stats.
Identities = 110/512 (21%), Positives = 191/512 (37%), Gaps = 45/512 (9%)
Query 32 SPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHF-TIPKEQYTIINRTASSVT 90
P + + SN + C+ K + V++ IVW N IP+ QY +++ S VT
Sbjct 334 FPPKILTSVGSNVSFHCIYKNENKI---VSSKKIVWWMNLAEKIPQSQYDVVSDHVSKVT 390
Query 91 FTDIAS--------LNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKM 142
F ++ + CN +Y I + + E +L+ KM
Sbjct 391 FFNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGHLT-------KM 443
Query 143 RCEWDGGRE-----THLETNFTLKSEWA--------THKFADCKAKRDTPTSCTVDYSTV 189
C W + L+ + S + K DC + D C
Sbjct 444 TCRWSTNTIQSLAGSTLQLRYRRSSLYCFDIPSIHPISKPKDCYLQSDGFYECVFQ-PIF 502
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+W+ + LG + S P VKP PP ++ + + +LK++W P
Sbjct 503 LLSGYTMWIRINHPLGSLDSPPTCVLPDSVVKPLPPSSVKAEIIKNIG-LLKISWEKPVF 561
Query 250 KSVIILKYNIQYRTKDAS-TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
L++ I+Y W D S S V D Y ++RC + DG G
Sbjct 562 PEN-NLQFQIRYGLSGKEIQWKMYDVYDAKSKSVSLPVPDF--CAVYAVQVRCKRSDGLG 618
Query 309 YWSDWSEEASGITYE-DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
WS+WS A + + P + P FW I+ + + V L+WK L E+ + Y
Sbjct 619 LWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNESLCSVQRYV 678
Query 368 VT-LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
+ T N TK T T + T+ N +G S A + +
Sbjct 679 INHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSIGASVANFNLTFSWPMSKVNI 738
Query 427 VMDLKAFP-KDNMLWVEWTTPRES--VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
V L A+P + + + W + +I+EW L++ W + +V + Y+
Sbjct 739 VQSLSAYPLNSSCVILSWILSPSDYKLMYFIIEWKNLNEDGE--IKWLRISSSVKKYYIH 796
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
+ + Y ++ P++ +G G P+ I ++ +
Sbjct 797 DHFIPIEKYQFSLYPIFMEGVGKPKIINSFAQ 828
Score = 86.1 bits (211), Expect = 9e-16, Method: Composition-based stats.
Identities = 42/207 (20%), Positives = 79/207 (38%), Gaps = 30/207 (14%)
Query 208 TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS 267
S ++ P+ VKP+PP L + +++ + LK++W++P + L+Y ++Y +
Sbjct 221 QSPLMSVQPINMVKPDPPLGLRMEITDDGN--LKISWSSPPLVP-FPLQYEVKYSENSTT 277
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
I D + +S V + P + Y ++R + DG G WSDWS T +D
Sbjct 278 V---IREADKIVSATSLLVDGILPGSSYEVQVRGKRLDGPGIWSDWSTP-HVFTTQDVIY 333
Query 328 KAPSFWYKI-----------DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
P + + + + + + W L Y+V
Sbjct 334 FPPKILTSVGSNVSFHCIYKNENKIVSSKKI-VWWMNLAEKIPQS---QYDV-------- 381
Query 377 LQNYTVNATKLTVNLTNDRYLATLTVR 403
+ ++ T +N T R T
Sbjct 382 VSDHVSKVTFFNLNETKPRGKFTYDAV 408
Score = 56.4 bits (134), Expect = 1e-06, Method: Composition-based stats.
Identities = 69/486 (14%), Positives = 155/486 (32%), Gaps = 59/486 (12%)
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ-----NYTVNATKLTVNLTNDRYLATLT 401
+++ W+ E N L +++ +Q Y + +++ + + + +
Sbjct 552 LKISWEKPVFPENN---LQFQIRYGLSGKEIQWKMYDVYDAKSKSVSLPVPDFCAVYAVQ 608
Query 402 VRNLVGK--------SDAAVLTIPACDFQATHP----VMDLKAFPKDNMLWVEWTTPRE- 448
VR S+ A + P +++ K+ + + W +
Sbjct 609 VRCKRSDGLGLWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKN 668
Query 449 ----SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
SV++Y++ + C W ++ G + L + + +TV + + G
Sbjct 669 ESLCSVQRYVI-----NHHTSCNGTWSEDVGNHTKF---TFLWTEQAHTVTVLAINSIGA 720
Query 505 GSPESIKAYL-KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
+ + + ++ + + +L W P D + + I ++ +
Sbjct 721 SVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVILSWILSPSDY---KLMYFIIEWKNLNE 777
Query 564 NETAVNVDSS---HTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIE 619
+ + S Y Y + EG GK +F + + +
Sbjct 778 DGEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFAQDNTEKHQND 837
Query 620 AIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPP---RHNF 676
A + + + +++L + +KK W +VP+P AQ P H F
Sbjct 838 AGLYVIVPVIISSSILLLGTLLILHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLF 897
Query 677 NSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSS 736
+ G I + K ++ ++ + GS C+S
Sbjct 898 IKHTASVTCGPLLLEPE-TISEDISVDTSWKNKD-EMVPTTVVSLLSTTDLEKGSVCISD 955
Query 737 SRPSISSSDEN------ESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQ------ 784
S++ S+ E V+Y+T++ + + Q S T+
Sbjct 956 QFNSVNFSEAEGTEVTCEDESQRQPFVKYATLISNSKPSETDEEQGLINSSVTKCFSSKN 1015
Query 785 -PLLDS 789
PL DS
Sbjct 1016 SPLKDS 1021
Score = 39.8 bits (91), Expect = 0.13, Method: Composition-based stats.
Identities = 19/115 (17%), Positives = 43/115 (37%), Gaps = 3/115 (3%)
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM-LWVEWTTPRESV 450
ND L L + + + ++++ + P + L+ D+ L + W++P +
Sbjct 203 LNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPLGLRMEITDDGNLKISWSSPP--L 260
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
+ L++ V + + + + L + Y + V DGPG
Sbjct 261 VPFPLQYEVKYSENSTTVIREADKIVSATSLLVDGILPGSSYEVQVRGKRLDGPG 315
>sp|O02671|LEPR_PIG Leptin receptor OS=Sus scrofa OX=9823 GN=LEPR
PE=2 SV=3
Length=1165
Score = 361 bits (925), Expect = 5e-107, Method: Composition-based stats.
Identities = 116/514 (23%), Positives = 201/514 (39%), Gaps = 45/514 (9%)
Query 32 SPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHF-TIPKEQYTIINRTASSVT 90
P + + SN + C+ K + V++ IVW N IP+ QY ++ S VT
Sbjct 336 FPPKILTSVGSNISFHCIYKNENKI---VSSKKIVWWMNLAEKIPQSQYDVVGDHVSKVT 392
Query 91 FTDIAS--------LNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKM 142
F ++ + + CN +Y I + + E L+ KM
Sbjct 393 FPNMNATKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLT-------KM 445
Query 143 RCEWDGGRE-----THLETNFTLKSEWAT--------HKFADCKAKRDTPTSCTVDYSTV 189
C W + L+ + S + + + DC+ +RD C
Sbjct 446 TCRWSTNAIQSLVGSTLQLRYHRSSLYCSDVPSVHPISEPKDCQLQRDGFYECIFQ-PIF 504
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+W+ + LG + S P VKP PP ++ + ++ +LK++W P
Sbjct 505 LLSGYTMWIRINHPLGSLDSPPTCVIPDSVVKPLPPSSVKAEITAKIG-LLKISWEKPVF 563
Query 250 KSVIILKYNIQYRTKDAS-TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
L++ I+Y W DT +S V DL Y ++RC + DG G
Sbjct 564 PEN-NLQFQIRYGLSGKEVQWKIYEVYDTKLKSTSLPVPDL--CAVYAVQVRCKRLDGLG 620
Query 309 YWSDWSEEA-SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
YWS+WS A + +T P + P FW I+ T+ R + L+WK L ++ + Y
Sbjct 621 YWSNWSTPAYTVVTDVKVPIRGPEFWRIINEDATKKERNITLLWKPLMKNDSLCSVRSYV 680
Query 368 VT-LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
V T N TKLT T + T+ N +G S A + +
Sbjct 681 VKHHTSRHGTWSEDVGNHTKLTFLWTEQAHSVTVLAVNSIGASSANFNLTFSWPMSKVNI 740
Query 427 VMDLKAFP-KDNMLWVEWTTPRES--VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
V L A+P + + + W + +ILEW +L++ W + +V + Y+
Sbjct 741 VQSLSAYPLNSSCVGLSWLLSPSDYNLMYFILEWKILNEDHE--IKWLRIPSSVKKYYIH 798
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
+ + Y ++ P++ +G G P+ I ++ +
Sbjct 799 DHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDG 832
Score = 82.6 bits (202), Expect = 1e-14, Method: Composition-based stats.
Identities = 30/113 (27%), Positives = 57/113 (50%), Gaps = 6/113 (5%)
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST 268
S ++ P+ VKP+PP L + ++ + LK++W++P++ L+Y ++Y +
Sbjct 224 SPLMSVQPINVVKPDPPLGLHMEITDTGN--LKISWSSPTLVP-FQLQYQVKYSENSTTN 280
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+ D + +S V + P + Y ++R + DG G WSDWS + T
Sbjct 281 MRE---ADEIVSDTSLLVDSVLPGSSYEVQVRGKRLDGPGIWSDWSTPFTFTT 330
Score = 65.6 bits (158), Expect = 2e-09, Method: Composition-based stats.
Identities = 77/516 (15%), Positives = 157/516 (30%), Gaps = 54/516 (10%)
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
+ + + P K + + G +++ W+ E N L +++
Sbjct 525 PPTCVIPDSVVKPLPPSSVKAEITAKIGL--LKISWEKPVFPENN---LQFQIRYGLSGK 579
Query 376 HLQ-------NYTVNATKLTVNLTNDRYLATLTVRNLVG------KSDAAVLTIPACDFQ 422
+Q + + +T L V Y + + L G S A +
Sbjct 580 EVQWKIYEVYDTKLKSTSLPVPDLCAVYAVQVRCKRLDGLGYWSNWSTPAYTVVTDVKVP 639
Query 423 ATHP----VMDLKAFPKDNMLWVEWTTPRE-----SVKKYILEWCVLSDKAPCITDWQQE 473
P +++ A K+ + + W + SV+ Y+++ W ++
Sbjct 640 IRGPEFWRIINEDATKKERNITLLWKPLMKNDSLCSVRSYVVK-----HHTSRHGTWSED 694
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL-KQAPPSKGPTVRTKKVGK 532
G + L + + +TV V + G S + + + ++ +
Sbjct 695 VGNHTK---LTFLWTEQAHSVTVLAVNSIGASSANFNLTFSWPMSKVNIVQSLSAYPLNS 751
Query 533 NEAVLEWDQLPVD-VQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
+ L W P D FI + I + S Y Y
Sbjct 752 SCVGLSWLLSPSDYNLMYFILEWKILNEDHEIKWLRIP-SSVKKYYIHDHFIPIEKYQFS 810
Query 592 MAA--YTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKK 649
+ G + + + V+ + LLG L ++R +KK
Sbjct 811 LYPIFMEGVGKPKIINSFTQDGEKHRNDAGLYVIVPIIISSSILLLGTLLMSHQR--MKK 868
Query 650 HIWPNVPDPSKSHIAQWSPHTPP---RHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPE 706
W +VP+P AQ P H F + + G I +
Sbjct 869 LFWEDVPNPKNCSWAQGLNFQKPETFEHLFIKHTESVTFGPLLLEPET-ISEDISVDTSW 927
Query 707 DLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSS-------TVQY 759
K ++ ++ + + SS S + S + E ES + T +++Y
Sbjct 928 KNKD-EMVPPTTVSLLLTTPDLEKSSICISDQRSSAHFSEAESMEITREDENRRQPSIKY 986
Query 760 STVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPED 795
+T++ S + Q S ++ S P++
Sbjct 987 ATLLSSPKSGETEQEQELVSSLVSRCFSSSNSLPKE 1022
Score = 38.7 bits (88), Expect = 0.35, Method: Composition-based stats.
Identities = 17/119 (14%), Positives = 42/119 (35%), Gaps = 6/119 (5%)
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNM-LWVEWTTPRESVKKYILEWCVLSDKAPCITD 469
+ ++++ + P + L D L + W++P + + L++ V +
Sbjct 224 SPLMSVQPINVVKPDPPLGLHMEITDTGNLKISWSSPT--LVPFQLQYQVKYSENSTTNM 281
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG---SPESIKAYLKQAPPSKGPTV 525
+ ++ + L ++ Y + V DGPG + + Q P +
Sbjct 282 READEIVSDTSLLVDSVLPGSSYEVQVRGKRLDGPGIWSDWSTPFTFTTQDVIYFPPKI 340
>sp|Q6UWB1|I27RA_HUMAN Interleukin-27 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL27RA PE=1 SV=2
Length=636
Score = 309 bits (790), Expect = 2e-92, Method: Composition-based stats.
Identities = 115/588 (20%), Positives = 200/588 (34%), Gaps = 35/588 (6%)
Query 132 LSCI-VNEGKKMRCEWDGGRETHLETNFTLKS-EWATHKFADCKAKRDTPTSCTVDYSTV 189
L C V + C W+ + + L+S ++ ++K
Sbjct 39 LQCYGVGPLGDLNCSWEPLGDLGAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQLT 98
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH-NLSVINSEELSSILKLTWTNPS 248
+ VW G+ + + ++KPN P V SE+ + W P+
Sbjct 99 MSDKLLVW---GTKAGQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDDPLEATVHWAPPT 155
Query 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
S +L YR + W+ + PE + +QDL+ T Y RC E +
Sbjct 156 WPSHKVLICQFHYRRCQEAAWTLLEPELKTIPLTPVEIQDLELATGYKVYGRCRMEKEED 215
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
W +WS S T PS W + T G L+WK G +
Sbjct 216 LWGEWSPILSFQTP---PSAPKDVWVSGNLCGTPGGEEPLLLWKAP------GPCVQVSY 266
Query 369 TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+ W + T + + A ++ N L++ D + +
Sbjct 267 KVWFWVGGRELSPEGITCCCSLIPSGAEWARVSAVNATSWEPLTNLSLVCLDSASAPRSV 326
Query 429 DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
+ + L V W +++++W D + +W + L GN
Sbjct 327 AVSSIAGSTELLVTWQPGPGEPLEHVVDWARDGDPLEKL-NWVRLPPGNLSALLPGNFTV 385
Query 489 SKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV-RTKKVGKNEAVLEWDQLPVDVQ 547
Y ITVT V A G S S+ + ++ P GPT+ R + + W ++P
Sbjct 386 GVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQL 445
Query 548 NGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEF 606
G + +YT+ ++ +NV + TL L + + A T G G GP
Sbjct 446 RGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGPC-ELWVTASTIAGQGPPGPIL 504
Query 607 TFTTPKFAQGEIEAIVVPVCLAFLL----TTLLGVLFCFNKR-DLIKKHIWPNVPDPSKS 661
P + L +L C++ R ++ + +W VPDP+ S
Sbjct 505 RLHLPDNTLRWKVLPGILFLWGLFLLGCGLSLATSGRCYHLRHKVLPRWVWEKVPDPANS 564
Query 662 HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLK 709
Q PH +Q+ D+ ++E+E + P E +
Sbjct 565 SSGQ--PHM---------EQVPEAQPLGDLPILEVEEMEPPPVMESSQ 601
>sp|O70394|I27RA_MOUSE Interleukin-27 receptor subunit alpha OS=Mus
musculus OX=10090 GN=Il27ra PE=1 SV=2
Length=623
Score = 308 bits (788), Expect = 3e-92, Method: Composition-based stats.
Identities = 121/595 (20%), Positives = 200/595 (34%), Gaps = 39/595 (7%)
Query 125 PPEKPKNLSC-IVNEGKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSC 182
P P L C V + C W+ G + ++ ++ + K
Sbjct 27 PHGSPGPLQCYSVGPLGILNCSWEPLGDLETPPVLYHQSQKYHPNRVWEVKVPSKQSWVT 86
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS-VINSEELSSILK 241
+ +W G+ ++ + ++KP+ P S V SEE +
Sbjct 87 IPREQFTMADKLLIW---GTQKGRPLWSSVSVNLETQMKPDTPQIFSQVDISEEATLEAT 143
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+ W P +L +Y+ A TW+++ P+ + +Q+L+P T Y RC
Sbjct 144 VQWAPPVWPPQKVLICQFRYKECQAETWTRLEPQLKTDGLTPVEMQNLEPGTCYQVSGRC 203
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
E+G W +WS S T W T G R LVWK P
Sbjct 204 QVENGY-PWGEWSSPLSFQTP---FLDPEDVWVSGTVCETSGKRAALLVWKDPRPCVQ-- 257
Query 362 KILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+ Y V V + A ++ N L++
Sbjct 258 --VTYTVWFGAGDITTTQEEV--PCCKSPVPAWMEWAVVSPGNSTSWVPPTNLSLVCLAP 313
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
++ + + + + V W +Y+++W D + +W + T
Sbjct 314 ESAPCDVGVSSADGSPGIKVTWKQGTRKPLEYVVDWAQDGDSLDKL-NWTRLPPGNLSTL 372
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV-RTKKVGKNEAVLEWD 540
L G Y ITVT VY+ G + S+ + ++ P GP V R V+ W
Sbjct 373 LPGEFKGGVPYRITVTAVYSGGLAAAPSVWGFREELVPLAGPAVWRLPDDPPGTPVVAWG 432
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
++P G +YT ++ + NV S TL +L + + + G
Sbjct 433 EVPRHQLRGQATHYTFCIQSRGLSTVCRNVSSQTQTATLPNLHLGSFKLWVTVSTVAGQG 492
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGV------LFCFNKRDLIKKH---- 650
GP + P I +P L+ L+G C R L +H
Sbjct 493 PPGPNLSLHLPD---NRIRWKALPWFLSLWGLLLMGCGLSLASTRCLQARCLHWRHKLLP 549
Query 651 --IWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKP 703
IW VPDP+ S+ Q P S Q DG +V VE++ + P
Sbjct 550 QWIWERVPDPANSNSGQ------PYIKEVSLPQPPKDGPILEVEEVELQPVVESP 598
>sp|Q6V4S5|SDK2_MOUSE Protein sidekick-2 OS=Mus musculus OX=10090
GN=Sdk2 PE=1 SV=1
Length=2176
Score = 312 bits (800), Expect = 3e-88, Method: Composition-based stats.
Identities = 129/619 (21%), Positives = 216/619 (35%), Gaps = 70/619 (11%)
Query 79 YTIINRTASSVTFTDI---ASLNIQLTC-NILTFGQLEQNVYGITIISGLPPEKPKNLSC 134
+T+ +R T D+ +Q+ N + G Q V G T S +P P N+S
Sbjct 1154 HTVQDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSQAVVGRTRES-VPSSGPTNVSA 1212
Query 135 IVNEGKKMRCEWD-------GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
+ M W G + + K + +F + T
Sbjct 1213 LATTSSSMLVRWSEIPEADRNGLVLGYKVRYKEKDSDSQPRFWLVEGNSSRSAQLTGLGK 1272
Query 188 TVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+V EV V A +G S + P PP + + E ++ ++L W
Sbjct 1273 ---YVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGI--LFPEVRTTSVRLIWQP 1327
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P+ + IIL Y I +R +A+T + E A + + LKP + Y+FRI G
Sbjct 1328 PAAPNGIILAYQITHRL-NATTANTATVEVLAPSARQYMATGLKPESVYLFRITAQTRKG 1386
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
W + +E A +T E R P + + R+V L W+ P + + Y
Sbjct 1387 ---WGEAAE-ALVVTTEKRDRPQPPSKPVVQQEDVKA-RSVLLSWE--PGSDGLSPVRYY 1439
Query 367 EVTLTR-----WKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPAC 419
+ W H + + NA+ TV+ Y + N +G S+ + +
Sbjct 1440 TIQTRELPSGRWALHSASVSHNASAFTVDRLKPFTSYKFRVKATNDIGDSEFSEESESLT 1499
Query 420 DFQATH--PVMDLKAFPKDN-MLWVEWTTPRESVKKYI-----LEWCVLSDKA------- 464
QA L P + + W P E I + + L
Sbjct 1500 TLQAAPDEAPTILSVTPHTTTSVLIRWQPPSEDKINGILLGFRIRYRELLYDGLRGFTLR 1559
Query 465 ------------PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIK 511
+ + Y NL++ + Y I ++ A G G +
Sbjct 1560 GINNPGAKWAELTSLYSMRNLTRPSLTQYELDNLSKHRRYEIRMSIYNAVGEGPLSPPQE 1619
Query 512 AYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN---ETA 567
++ +A P+ P V + + W+ P+D QNG I+ Y I++ + E
Sbjct 1620 VFVGEAVPTAAPQNVAIHSATATQLDVTWEPPPLDNQNGDIQGYKIYFWEVQRRNLTERV 1679
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
+ + L +LT T YMV +AA+ G DGP +TP Q + A P +
Sbjct 1680 KTLFLAENSVKLKNLTGYTAYMVSVAAFNAAG--DGPR---STPTRGQTQQAAPSAPGSV 1734
Query 628 AFLLTTLLGVLFCFNKRDL 646
F T V ++
Sbjct 1735 KFSELTTTSVNVSWDAPQF 1753
Score = 197 bits (499), Expect = 4e-50, Method: Composition-based stats.
Identities = 95/511 (19%), Positives = 159/511 (31%), Gaps = 36/511 (7%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P +LS ++ W + G + + T + + E T
Sbjct 898 VPGPVGHLSFNDILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEY 957
Query 184 VDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
+ V A + G+ S V P P NL + N + L
Sbjct 958 RVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGAPTNLGISNIG--PRSVTL 1015
Query 243 TWTNPSIKSVIILKYNIQYRTK---DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ I ++ ++ + + W I S V DL PFT Y FR+
Sbjct 1016 QFRPGYDGKTSISRWVVEAQVGVIGEGEEWLLIYQLGNEPDARSMEVPDLNPFTYYSFRM 1075
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
R + G S S + T + P AP+ T ++ L W LP E
Sbjct 1076 RQVNIVGTSPPSQPSRK--IQTLQAPPDIAPANVTL----RTASETSLWLRWMPLPEMEY 1129
Query 360 NGKI--LDYEVTLTRWKSHLQNYTVNAT-----KLTVNLTN--DRYLATLTVRNLVGKSD 410
NG + Y++ R H + + + T+ Y + N +G
Sbjct 1130 NGNPESVGYKIKYGRSDGHGKTLSHTVQDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGP 1189
Query 411 AAVLTI-PACDFQATHPVMDLKAFP-KDNMLWVEWTT-PRESVKKYILEWCVLS---DKA 464
+ + + + ++ A + + V W+ P +L + V D
Sbjct 1190 WSQAVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEIPEADRNGLVLGYKVRYKEKDSD 1249
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE--SIKAYLKQAPPSKG 522
W +G R+ L + Y + V G GSP I P
Sbjct 1250 SQPRFWL-VEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPP 1308
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD---SSHTEYTL 579
+ +V L W P NG I Y I +R V+ S +Y
Sbjct 1309 MGILFPEVRTTSVRLIWQ--PPAAPNGIILAYQITHRLNATTANTATVEVLAPSARQYMA 1366
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ L +++Y+ R+ A T +G + E T
Sbjct 1367 TGLKPESVYLFRITAQTRKGWGEAAEALVVT 1397
Score = 191 bits (484), Expect = 3e-48, Method: Composition-based stats.
Identities = 95/532 (18%), Positives = 166/532 (31%), Gaps = 63/532 (12%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDT---- 178
P P + +R W N + + TH+ A T
Sbjct 1302 DDVPGPPMGILFPEVRTTSVRLIWQPPAAP----NGIILAYQITHRLNATTANTATVEVL 1357
Query 179 --PTSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
+ + A+ G ++ + + +P PP V +
Sbjct 1358 APSARQYMATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPVVQQEDV 1417
Query 236 LSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+ + L+W S + Y IQ R + W + + S+FTV LKPFT Y
Sbjct 1418 KARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRW-ALHSASVSHNASAFTVDRLKPFTSY 1476
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
FR++ + G +S+ E S T + P +AP+ + P T +V + W+
Sbjct 1477 KFRVKATNDIGDSEFSE--ESESLTTLQAAPDEAPTI-LSVTPHTTT---SVLIRWQPPS 1530
Query 356 PFEANGKILDYEVTLTR--------------------WKSHLQNYTVNA------TKLTV 389
+ NG +L + + W Y++ T+ +
Sbjct 1531 EDKINGILLGFRIRYRELLYDGLRGFTLRGINNPGAKWAELTSLYSMRNLTRPSLTQYEL 1590
Query 390 NLTND--RYLATLTVRNLVGKSD--AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT 445
+ + RY +++ N VG+ P L V W
Sbjct 1591 DNLSKHRRYEIRMSIYNAVGEGPLSPPQEVFVGEAVPTAAPQNVAIHSATATQLDVTWEP 1650
Query 446 PRESVKKY-ILEWCVLSDK--APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD 502
P + I + + + +T+ + + NL Y+++V A
Sbjct 1651 PPLDNQNGDIQGYKIYFWEVQRRNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAA 1710
Query 503 GPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR-- 559
G G + +QA PS +V+ ++ + WD NG + Y + Y
Sbjct 1711 GDGPRSTPTRGQTQQAAPSAPGSVKFSELTTTSVNVSWDA--PQFPNGPLEGYRLVYEPC 1768
Query 560 -TIIGNETAVNVDSSHTE---YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
+ G V VD + L Y R+ A T GPE
Sbjct 1769 TPVDGVSKIVTVDVKGNSPLWLKVKDLAEGMTYRFRIKAKT---FTYGPEIE 1817
Score = 188 bits (476), Expect = 3e-47, Method: Composition-based stats.
Identities = 124/813 (15%), Positives = 238/813 (29%), Gaps = 102/813 (13%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P V + C + I W+ + + T
Sbjct 412 PLDSTVIDGMSVVLAC-------ETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSL 464
Query 93 DIASLNIQLTCNILTFGQ--------LEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRC 144
I+ +I V P P++ S I M C
Sbjct 465 LISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKP---PQDQSVIKGTQASMVC 521
Query 145 EWDGGRETHLETNFTLKSEWATHKFA---DCKAKRDTPTSCTVDYSTVY---FVNIEVWV 198
+ T++ W + + + ++ S + V
Sbjct 522 ------GVTHDPRVTVRYVWEKDGATLAVETNPRIRLDRNGSLHISQTWSGDIGTYTCRV 575
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
L +D N + P+ P + S + LTW P + +++Y
Sbjct 576 -----LSAGGNDSRNAHLRVRQLPHAPEHPVATLSTVERRAINLTWAKPFDGNSPLMRYV 630
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
++ +A I +S V+ L P Y FR+ + + GKG +S +E S
Sbjct 631 LEMSENNAPW--TILLASVDPEATSVMVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVS 688
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
E+ P+ P + + +++ + W+ P NG + Y + +
Sbjct 689 L--PEEPPTAPPQNVI----ASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVG 742
Query 379 NYTVNATKLTVNLTN-------DRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDL 430
N T VN Y + N G ++ +T T P ++
Sbjct 743 YQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNV 802
Query 431 KAFPK-DNMLWVEWTTPRESVKKYI-LEWCVLSDK---APCITDWQQEDGTVHRTYL--R 483
A + W P I + +++ + +T ++
Sbjct 803 HAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPAQEEEVTMVTARPNFQDSIHVGFV 862
Query 484 GNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
L + Y +V G G + P + + + W +
Sbjct 863 SGLKKFTEYFTSVLCFTTPGDGPRSSPQLVRTHEDVPGPVGHLSFNDILDTSLKVSWQE- 921
Query 543 PVDVQNGFIRNYTIFYRTIIGNETAVN--VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
+NG + Y I + T V + + EY ++ LT+ T Y + +AA T +G
Sbjct 922 -PGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQ 980
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
T + + E P L V F + K
Sbjct 981 GQVSASTIS----SGVPPELPGAPTNLGISNIGPRSVTLQFR-------PGYD-----GK 1024
Query 661 SHIAQWS--PHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEK 718
+ I++W +Y GN D +E+ + + F+ +
Sbjct 1025 TSISRWVVEAQVGVIGEGEEWLLIYQLGNEPDARSMEVPDLNP-------FTYYSFRMRQ 1077
Query 719 INTEGHSSGIGGSSCMSS--SRPSISSSDEN-ESSQNTSSTVQYSTVVHSGYRHQVPSVQ 775
+N G S S + + + P I+ ++ ++ TS +++ + Y SV
Sbjct 1078 VNIVGTSPPSQPSRKIQTLQAPPDIAPANVTLRTASETSLWLRWMPLPEMEYNGNPESVG 1137
Query 776 V---FSRSE--------STQPLLDSEERPEDLQ 797
+ RS+ + Q ++ E EDL+
Sbjct 1138 YKIKYGRSDGHGKTLSHTVQDRVEREYTIEDLE 1170
Score = 176 bits (446), Expect = 1e-43, Method: Composition-based stats.
Identities = 91/575 (16%), Positives = 170/575 (30%), Gaps = 61/575 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNF-TLKSEWATHKFADCKAKRDTPTSCT 183
PP KP + + + + W+ G + + T+++ + + +
Sbjct 1406 PPSKPV-VQQEDVKARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASA 1464
Query 184 VDYSTVY-FVNIEVWVEAENALGKVTSDHIN--FDPVYKVKPNPPHNLSVINSEELSSIL 240
+ F + + V+A N +G + + P LSV + ++ +
Sbjct 1465 FTVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSV--TPHTTTSV 1522
Query 241 KLTWTNPSIK--SVIILKYNIQYRT---------------KDASTWSQIPP-----EDTA 278
+ W PS + I+L + I+YR + W+++ T
Sbjct 1523 LIRWQPPSEDKINGILLGFRIRYRELLYDGLRGFTLRGINNPGAKWAELTSLYSMRNLTR 1582
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+ + + + +L Y R+ G+G S E G E P+ AP
Sbjct 1583 PSLTQYELDNLSKHRRYEIRMSIYNAVGEGPLSPPQEVFVG---EAVPTAAPQNVAIHSA 1639
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL------QNYTVNATKLTVNLT 392
+ TQ + + W+ P NG I Y++ + + + NLT
Sbjct 1640 TATQ----LDVTWEPPPLDNQNGDIQGYKIYFWEVQRRNLTERVKTLFLAENSVKLKNLT 1695
Query 393 N-DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK-AFPKDNMLWVEWTTPR--- 447
Y+ ++ N G + T A +K + + V W P+
Sbjct 1696 GYTAYMVSVAAFNAAGDGPRSTPTRGQTQQAAPSAPGSVKFSELTTTSVNVSWDAPQFPN 1755
Query 448 ESVKKYILEWCVLSD-KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
++ Y L + + G +LAE Y +
Sbjct 1756 GPLEGYRLVYEPCTPVDGVSKIVTVDVKGNSPLWLKVKDLAEGMTYRFRIKAKTFTYGPE 1815
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET 566
E+ P V + + W G I Y I R
Sbjct 1816 IEANITTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDP--GKGPITRYVIEARPSDEGLW 1873
Query 567 AVNVDSSHTEYT-----LSSLTSDTLYMVRMAAYTDE--GGKDGPEFTFTTPKFAQGEIE 619
+ + E T + L Y R+ A D G P + K + E
Sbjct 1874 DILIKDIPKEVTSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKASPFYEE 1933
Query 620 AI----VVPVCLAFLLTTLLGVLFCFNKRDLIKKH 650
+ V L F+L + ++ + KK
Sbjct 1934 WWFLVVIALVGLIFILLLVFVLIIRGQSKKYSKKT 1968
Score = 168 bits (426), Expect = 3e-41, Method: Composition-based stats.
Identities = 132/797 (17%), Positives = 248/797 (31%), Gaps = 94/797 (12%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHF--TIPKEQYTIINRTASSVT 90
P+ V + + VC V Y VW+ + + ++R S
Sbjct 506 PQDQSVIKGTQASMVC----GVTHDPRVTVRY-VWEKDGATLAVETNPRIRLDRNGSLHI 560
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNL--SCIVNEGKKMRCEWDG 148
+ TC +L+ G + + P P++ + E + + W
Sbjct 561 SQTWSGDIGTYTCRVLSAGGNDSR--NAHLRVRQLPHAPEHPVATLSTVERRAINLTWAK 618
Query 149 GRETHLET-NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV 207
+ + + L+ + A D + + V + + + A N +GK
Sbjct 619 PFDGNSPLMRYVLEMSENNAPWTILLASVDPEATSVMVKGLVPARSYQFRLCAVNDVGKG 678
Query 208 --TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP--SIKSVIILKYNIQYRT 263
+ D + PP N VI S + + + W P S ++ I+ Y I+Y
Sbjct 679 QFSKDTERVSLPEEPPTAPPQN--VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCL 736
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
Q T + ++ ++DL +T Y + G G +S + + T +
Sbjct 737 AGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSS---KVTEWTLQ 792
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN 383
P+ P + + T++ W P NG Y++ + V
Sbjct 793 GVPTVPPGNVH----AEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPAQEEEVTMVT 848
Query 384 ATK----------LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK-A 432
A ++ Y ++ G + + PV L
Sbjct 849 ARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSSPQLVRTHEDVPGPVGHLSFN 908
Query 433 FPKDNMLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
D L V W P E + Y + W + +T + V Y L
Sbjct 909 DILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYL---PNVTLEYRVTGLTAL 965
Query 490 KCYLITVTPVYADGPG--SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
Y I V + + G G S +I + + P + +G L++ P
Sbjct 966 TTYTIEVAAMTSKGQGQVSASTISSGVPPELPGAPTNLGISNIGPRSVTLQFR--PGYDG 1023
Query 548 NGFIRNYTIFYRTIIGNETAVNV-------DSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
I + + + + E + + + L T Y RM G
Sbjct 1024 KTSISRWVVEAQVGVIGEGEEWLLIYQLGNEPDARSMEVPDLNPFTYYSFRMRQVNIVGT 1083
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
P +I+ + P +A TL
Sbjct 1084 SP--------PSQPSRKIQTLQAPPDIAPANVTLRTAS--------------------ET 1115
Query 661 SHIAQWSPHTPPRHNFNSKDQMY------SDGNFTDVSVVEIEANDKKPFPEDLKSLDLF 714
S +W P +N N + Y SDG+ +S + +++ EDL+ +
Sbjct 1116 SLWLRWMPLPEMEYNGNPESVGYKIKYGRSDGHGKTLSHTVQDRVEREYTIEDLEEWTEY 1175
Query 715 KKEKINTEGHSSGIGGSSCMSSSRPSISSS-DENESSQNTSST---VQYSTVVHSGYRHQ 770
+ + SG + + +R S+ SS N S+ T+S+ V++S + +
Sbjct 1176 RVQVQAFNAIGSGPWSQAVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEIPEADRNGL 1235
Query 771 VPSVQV-FSRSES-TQP 785
V +V + +S +QP
Sbjct 1236 VLGYKVRYKEKDSDSQP 1252
Score = 72.6 bits (176), Expect = 2e-11, Method: Composition-based stats.
Identities = 44/268 (16%), Positives = 80/268 (30%), Gaps = 17/268 (6%)
Query 64 YIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTC----NILTFGQLEQNVYGIT 119
I + E+ + +SV ++ + N G G T
Sbjct 1664 KIYFWEVQRRNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTRGQT 1723
Query 120 IISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN-FTLKSEWAT-----HKFADCK 173
+ P P ++ + WD + + + L E T K
Sbjct 1724 QQA--APSAPGSVKFSELTTTSVNVSWDAPQFPNGPLEGYRLVYEPCTPVDGVSKIVTVD 1781
Query 174 AKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS 233
K ++P V + ++A+ I + P V
Sbjct 1782 VKGNSPLWLKV-KDLAEGMTYRFRIKAKTF---TYGPEIEANITTGPGEGAPGPPGVPII 1837
Query 234 EELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS-TRSSFTVQDLKPF 292
SS + + W++ I +Y I+ R D W + + T +F++ LKP
Sbjct 1838 VRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKPG 1897
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGI 320
Y FR+ + + G G S S+
Sbjct 1898 VSYDFRVIAVNDYGFGTPSSPSQSVPAQ 1925
>sp|Q58EX2|SDK2_HUMAN Protein sidekick-2 OS=Homo sapiens OX=9606
GN=SDK2 PE=1 SV=3
Length=2172
Score = 302 bits (772), Expect = 1e-84, Method: Composition-based stats.
Identities = 128/619 (21%), Positives = 211/619 (34%), Gaps = 70/619 (11%)
Query 79 YTIINRTASSVTFTDI---ASLNIQLTC-NILTFGQLEQNVYGITIISGLPPEKPKNLSC 134
+ + +R T D+ +Q+ N + G Q V G T S +P P N+S
Sbjct 1150 HVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRES-VPSSGPTNVSA 1208
Query 135 IVNEGKKMRCEWD-------GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
+ M W G + + K +F + T
Sbjct 1209 LATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGK 1268
Query 188 TVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+V EV V A +G S + P PP + + E ++ ++L W
Sbjct 1269 ---YVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGI--LFPEVRTTSVRLIWQP 1323
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P+ + IIL Y I +R + + E A + +T LKP + Y+FRI G
Sbjct 1324 PAAPNGIILAYQITHRLNTTTA-NTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKG 1382
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
W + +E A +T E R P + + R+V L W+ P + + Y
Sbjct 1383 ---WGEAAE-ALVVTTEKRDRPQPPSRPMVQQEDVRA-RSVLLSWE--PGSDGLSPVRYY 1435
Query 367 EVTLTR-----WKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPAC 419
+ W H + + NA+ V+ Y + N +G S+ + +
Sbjct 1436 TIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLT 1495
Query 420 DFQATH--PVMDLKAFPKDN-MLWVEWTTPRESVKKYI-----LEWCVLSDKA------- 464
QA L P + + W P E I + + L +
Sbjct 1496 TLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLR 1555
Query 465 ------------PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-IK 511
+ + Y NL + + Y I ++ A G G +
Sbjct 1556 GINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQE 1615
Query 512 AYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF-YRTIIGN--ETA 567
++ +A P+ P V + + W+ P+D QNG I+ Y I+ + GN E
Sbjct 1616 VFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERV 1675
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
+ + L +LT T YMV +AA+ G DGP +TP Q + A P +
Sbjct 1676 KTLFLAENSVKLKNLTGYTAYMVSVAAFNAAG--DGPR---STPTQGQTQQAAPSAPSSV 1730
Query 628 AFLLTTLLGVLFCFNKRDL 646
F T V +
Sbjct 1731 KFSELTTTSVNVSWEAPQF 1749
Score = 201 bits (510), Expect = 2e-51, Method: Composition-based stats.
Identities = 97/511 (19%), Positives = 163/511 (32%), Gaps = 36/511 (7%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P +LS ++ W + G + + T + + E T
Sbjct 894 VPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEY 953
Query 184 VDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
+ V A + G+ S V P PP NL + N + L
Sbjct 954 RVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIG--PRSVTL 1011
Query 243 TWTNPSIKSVIILKYNIQYRTK---DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ I ++ ++ + + W I S V DL PFT Y FR+
Sbjct 1012 QFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRM 1071
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
R + G S S + T + P AP+ T ++ L W LP E
Sbjct 1072 RQVNIVGTSPPSQPSRK--IQTLQAPPDMAPANVSL----RTASETSLWLRWMPLPEMEY 1125
Query 360 NGKI--LDYEVTLTRWKSH-------LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD 410
NG + Y++ +R H +Q+ + Y + N +G
Sbjct 1126 NGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGP 1185
Query 411 AAVLTI-PACDFQATHPVMDLKAFP-KDNMLWVEWTTPRE-SVKKYILEWCVLSDKAPCI 467
+ + + + ++ A + + V W+ E +L + V+ +
Sbjct 1186 WSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSD 1245
Query 468 TD---WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE--SIKAYLKQAPPSKG 522
T W +G R+ L + Y + V G GSP I P
Sbjct 1246 TQPRFWL-VEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPP 1304
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD---SSHTEYTL 579
+ +V L W P NG I Y I +R V+ S +YT
Sbjct 1305 MGILFPEVRTTSVRLIWQ--PPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTA 1362
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ L +++Y+ R+ A T +G + E T
Sbjct 1363 TGLKPESVYLFRITAQTRKGWGEAAEALVVT 1393
Score = 192 bits (487), Expect = 1e-48, Method: Composition-based stats.
Identities = 93/528 (18%), Positives = 168/528 (32%), Gaps = 55/528 (10%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGR-ETHLETNFTLKSEWATHKFADCKAKRDTPT- 180
P P + +R W + + + T + P+
Sbjct 1298 DDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSA 1357
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTS-DHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ A+ G + + + + +P PP V + +
Sbjct 1358 RQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARS 1417
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L+W S + Y IQ R + W + + SSF V LKPFT Y FR+
Sbjct 1418 VLLSWEPGSDGLSPVRYYTIQTRELPSGRW-ALHSASVSHNASSFIVDRLKPFTSYKFRV 1476
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
+ + G +S+ E S T + P +AP+ + P T +V + W+ +
Sbjct 1477 KATNDIGDSEFSE--ESESLTTLQAAPDEAPTI-LSVTPHTTT---SVLIRWQPPAEDKI 1530
Query 360 NGKILDYEVTLTR--------------------WKSHLQNYTVNA------TKLTVNLTN 393
NG +L + + W Y++ T+ ++ N
Sbjct 1531 NGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLN 1590
Query 394 D--RYLATLTVRNLVGKSDAAVL-TIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRES 449
RY ++V N VG+ ++ + + T ++ L V W P
Sbjct 1591 KHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLD 1650
Query 450 VKKY-ILEWCVLSDKAPCITDWQQEDGTV--HRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ I + + +A ++ + NL Y+++V A G G
Sbjct 1651 SQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGP 1710
Query 507 PE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR---TII 562
+ +QA PS +V+ ++ + W+ NG + Y + Y +
Sbjct 1711 RSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEA--PQFPNGILEGYRLVYEPCSPVD 1768
Query 563 GNETAVNVDSSHTE---YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
G V VD + L Y R+ A T GPE
Sbjct 1769 GVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT---FTYGPEIE 1813
Score = 188 bits (477), Expect = 2e-47, Method: Composition-based stats.
Identities = 92/607 (15%), Positives = 180/607 (30%), Gaps = 57/607 (9%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P V + C + I W+ + + T
Sbjct 408 PLDSTVIDGMSVVLAC-------ETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSL 460
Query 93 DIASLNIQLTCNILTFGQ--------LEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRC 144
I+ +I V P P++ S I M C
Sbjct 461 LISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKP---PQDQSVIKGTQASMVC 517
Query 145 EWDGGRETHLETNFTLKSEWATHKFA---DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAE 201
+ T++ W + + + ++ S + +I +
Sbjct 518 ------GVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRV 571
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
+ G S + + P+ P + S + LTWT P + +++Y ++
Sbjct 572 ISAGGNDSRSAHLRV--RQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEM 629
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+A + +S TV+ L P Y FR+ + + GKG +S +E S
Sbjct 630 SENNAPW--TVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL-- 685
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
E+ P+ P + + +++ + W+ P NG + Y + +
Sbjct 686 PEEPPTAPPQNVI----ASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQF 741
Query 382 VNATKLTVNLTN-------DRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLKAF 433
N T VN Y + N G ++ +T T P ++ A
Sbjct 742 KNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAE 801
Query 434 PK-DNMLWVEWTTPRESVKKYI-LEWCVLSDKAPCITDWQQED--GTVHRTYLRG---NL 486
+ W P I + +++ + + + G L
Sbjct 802 ATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGL 861
Query 487 AESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
+ Y +V G G + P + ++ + W +
Sbjct 862 KKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQE--PG 919
Query 546 VQNGFIRNYTIFYRTIIGNETAVN--VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+NG + Y I + T V + + EY ++ LT+ T Y + +AA T +G
Sbjct 920 EKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQV 979
Query 604 PEFTFTT 610
T ++
Sbjct 980 SASTISS 986
Score = 176 bits (447), Expect = 9e-44, Method: Composition-based stats.
Identities = 89/575 (15%), Positives = 171/575 (30%), Gaps = 61/575 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNF-TLKSEWATHKFADCKAKRDTPTSCT 183
PP +P + + + W+ G + + T+++ + + + +
Sbjct 1402 PPSRPM-VQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASS 1460
Query 184 VDYSTVY-FVNIEVWVEAENALGKVTSDHIN--FDPVYKVKPNPPHNLSVINSEELSSIL 240
+ F + + V+A N +G + + P LSV + ++ +
Sbjct 1461 FIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSV--TPHTTTSV 1518
Query 241 KLTWTNPSIK--SVIILKYNIQYRT---------------KDASTWSQIPP-----EDTA 278
+ W P+ + I+L + I+YR +TW+++ +
Sbjct 1519 LIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSR 1578
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+ + + + +L Y R+ G+G S E G E P+ AP
Sbjct 1579 PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVG---EAVPTAAPRNVVVHGA 1635
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL------QNYTVNATKLTVNLT 392
+ TQ + + W+ P NG I Y++ + + + NLT
Sbjct 1636 TATQ----LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLT 1691
Query 393 N-DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK-AFPKDNMLWVEWTTPR--- 447
Y+ ++ N G + T A +K + + V W P+
Sbjct 1692 GYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPN 1751
Query 448 ESVKKYILEWCVLSD-KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
++ Y L + S G +LAE Y +
Sbjct 1752 GILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPE 1811
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET 566
E+ P V + + W G I Y I R
Sbjct 1812 IEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDP--GKGPITRYVIEARPSDEGLW 1869
Query 567 AVNVDS-----SHTEYTLSSLTSDTLYMVRMAAYTDE--GGKDGPEFTFTTPKFAQGEIE 619
+ + S +++ L Y R+ A D G P + K E
Sbjct 1870 DILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPFYEE 1929
Query 620 AI----VVPVCLAFLLTTLLGVLFCFNKRDLIKKH 650
+ V L F+L + ++ + KK
Sbjct 1930 WWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKT 1964
Score = 172 bits (435), Expect = 3e-42, Method: Composition-based stats.
Identities = 134/797 (17%), Positives = 250/797 (31%), Gaps = 94/797 (12%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTI--PKEQYTIINRTASSVT 90
P+ V + + VC V YI W+ + T+ ++R S
Sbjct 502 PQDQSVIKGTQASMVC----GVTHDPRVTIRYI-WEKDGATLGTESHPRIRLDRNGSLHI 556
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNL--SCIVNEGKKMRCEWDG 148
+ TC +++ G + + P P++ + E + + W
Sbjct 557 SQTWSGDIGTYTCRVISAGGNDSR--SAHLRVRQLPHAPEHPVATLSTVERRAINLTWTK 614
Query 149 GRETHLET-NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV 207
+ + + L+ + A D + V + + + A N +GK
Sbjct 615 PFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKG 674
Query 208 --TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP--SIKSVIILKYNIQYRT 263
+ D + PP N VI S + + + W P S ++ I+ Y I+Y
Sbjct 675 QFSKDTERVSLPEEPPTAPPQN--VIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCL 732
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
Q T + ++ ++DL +T Y + G G +S + + T +
Sbjct 733 AGLPVGYQFK-NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSS---KVTEWTLQ 788
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN 383
P+ P + + T++ W P NG Y++ + + V
Sbjct 789 GVPTVPPGNVH----AEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVT 844
Query 384 ATK----------LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK-A 432
A ++ Y ++ G + + PV L +
Sbjct 845 ARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFS 904
Query 433 FPKDNMLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
D L V W P E + Y + W + +T + V Y L
Sbjct 905 EILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYL---PNVTLEYRVTGLTAL 961
Query 490 KCYLITVTPVYADGPG--SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
Y I V + + G G S +I + + P + +G L++ P
Sbjct 962 TTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR--PGYDG 1019
Query 548 NGFIRNYTIFYRTIIGNETAVNV-------DSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
I + + + + E + + + L T Y RM G
Sbjct 1020 KTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGT 1079
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
P +I+ + P +A +L
Sbjct 1080 SP--------PSQPSRKIQTLQAPPDMAPANVSLRTAS--------------------ET 1111
Query 661 SHIAQWSPHTPPRHNFNSKDQMY------SDGNFTDVSVVEIEANDKKPFPEDLKSLDLF 714
S +W P +N N + Y SDG+ +S V + ++ EDL+ +
Sbjct 1112 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEY 1171
Query 715 KKEKINTEGHSSGIGGSSCMSSSRPSISSS-DENESSQNTSST---VQYSTVVHSGYRHQ 770
+ + SG + + +R S+ SS N S+ T+S+ V++S V +
Sbjct 1172 RVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGL 1231
Query 771 VPSVQV-FSRSES-TQP 785
V +V + +S TQP
Sbjct 1232 VLGYKVMYKEKDSDTQP 1248
Score = 90.7 bits (223), Expect = 5e-17, Method: Composition-based stats.
Identities = 51/324 (16%), Positives = 94/324 (29%), Gaps = 30/324 (9%)
Query 119 TIISG--LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE---TNFTLKSEWATHKFADCK 173
+ G +P P+N+ ++ W+ + + A +
Sbjct 1615 EVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTER 1674
Query 174 AKRDTPT-SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
K + + + V V A NA G + P+ P SV
Sbjct 1675 VKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPS--SVKF 1732
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKD-ASTWSQIPPEDTASTRS-SFTVQDLK 290
SE ++ + ++W P + I+ Y + Y S+I D V+DL
Sbjct 1733 SELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLA 1792
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
Y FRIR EA+ T + P I + + +
Sbjct 1793 EGVTYRFRIRAKTFTYG-----PEIEANVTTGPGEGAPGPPGVPII----VRYSSAIAIH 1843
Query 351 WKTLPPFEANGKILDYEVTLTR-----WKSHLQNYTVNATKLTVNL----TNDRYLATLT 401
W + P + G I Y + W +++ + T ++ Y +
Sbjct 1844 WSSGDPGK--GPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVI 1901
Query 402 VRNLVGKSDAAVLTIPACDFQATH 425
N G + + +A
Sbjct 1902 AVNDYGFGTPSSPSQSVPAQKANP 1925
>sp|Q8AV58|SDK1_CHICK Protein sidekick-1 OS=Gallus gallus OX=9031
GN=SDK1 PE=1 SV=1
Length=2169
Score = 299 bits (764), Expect = 1e-83, Method: Composition-based stats.
Identities = 136/610 (22%), Positives = 232/610 (38%), Gaps = 71/610 (12%)
Query 81 IINRTASSVTFTDI---ASLNIQLTC-NILTFGQLEQNVYGITIISGLPPEKPKNLSCIV 136
I +R T D+ +Q+ N + G + V G+ +P P+N+S
Sbjct 1181 ISDRLERECTIQDLEEWTEYELQIQAFNAIGAGPWNE-VVGVRTRESVPSAPPENVSAEA 1239
Query 137 NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAK------RDTPTSCTVDYSTVY 190
++ W E+ E N + +K D ++ R T +
Sbjct 1240 VSSTQILLTWSAVPES--EQNGLILGYKILYKAKDLDSEPRSQTVRGNHTQSCLLSGLRK 1297
Query 191 FVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+V E+ V A +G V S + + P PP + ++ E + +++ W P
Sbjct 1298 YVLYEIRVLAFTRIGDGVPSSPVLTERTKDDAPGPP--IRLVFPEVRLTSVRIVWQPPEE 1355
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ IIL Y I YR +S ++ + ST FT DL P + Y+FR G
Sbjct 1356 PNGIILGYQIAYRLASSSP-NKFTTVEVGSTVRQFTATDLTPESAYIFRTSAKTRQG--- 1411
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
W + E A+ IT E R AP P R++QL W +P + + I + V
Sbjct 1412 WGEPLE-ATVITTEKRERPAPPQ-QLTTPQSDVSSRSLQLHW--VPGSDGSSPIRYFTVQ 1467
Query 370 LTR-----WKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
+ W+++ + + AT + N Y + N +G SD + T Q
Sbjct 1468 VRELPNGDWQTYSSSISHEATSCIIESLNPFTSYKLRVKATNDIGDSDYSAETEAVTTLQ 1527
Query 423 ATH--PVMDLKAFPKD-NMLWVEWTTPR-ESVKKYILEWCVLSDK--------------- 463
P + P + + V+W P+ ES+ +L + + +
Sbjct 1528 DVPDEPPSSVLVTPHTTSSVLVQWQPPKAESLNGLLLGYRIYYRELDYDAGSATESKAVK 1587
Query 464 ---------APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-SIKAY 513
P + + TY L + K Y + +T G ++ +
Sbjct 1588 NPSALRAELTPQSSFKTVNSSSALTTYELTQLKKYKRYEVLMTAYNVIGESPTSTPVEVF 1647
Query 514 LKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT--IIGNETAVNV 570
+ +A P+ P ++ + ++ L WD P D QNG I+ Y I+Y + + V V
Sbjct 1648 VGEAAPAMAPQNIQVNSLSASQLELTWDPPPADSQNGNIQGYKIYYWEGDVQNDTEKVKV 1707
Query 571 DSSHTEYTLS-SLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAF 629
SS + + S +LTS T Y+V ++A+ G DGP + P + A P L F
Sbjct 1708 FSSLRQLSASKNLTSHTRYLVCISAFNAAG--DGPR---SRPSAGRTHQAAPSAPSFLVF 1762
Query 630 --LLTTLLGV 637
+ +T L V
Sbjct 1763 SEITSTTLNV 1772
Score = 206 bits (524), Expect = 3e-53, Method: Composition-based stats.
Identities = 103/623 (17%), Positives = 187/623 (30%), Gaps = 79/623 (13%)
Query 64 YIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNV----YGIT 119
I++K T+ S + + + +L F ++ V
Sbjct 1265 KILYKAKDLDSEPRSQTVRGNHTQSCLLSGLRKY-VLYEIRVLAFTRIGDGVPSSPVLTE 1323
Query 120 IISGLPPEKPKNLSCIVNEGKKMRCEWDGGRET-----HLETNFTLKSEWATHKFADCKA 174
P P L +R W E + + L S + +KF +
Sbjct 1324 RTKDDAPGPPIRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASS-SPNKFTTVEV 1382
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVY-KVKPNPPHNLSVINS 233
D + A+ G + +P PP L+ S
Sbjct 1383 GSTVRQFTATDLTPE--SAYIFRTSAKTRQGWGEPLEATVITTEKRERPAPPQQLTTPQS 1440
Query 234 EELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
+ S L+L W S S I + +Q R W + +S ++ L PFT
Sbjct 1441 DVSSRSLQLHWVPGSDGSSPIRYFTVQVRELPNGDWQTYS-SSISHEATSCIIESLNPFT 1499
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
Y R++ + G +S +E + T +D P + PS + P T +V + W+
Sbjct 1500 SYKLRVKATNDIGDSDYS--AETEAVTTLQDVPDEPPSS-VLVTPHTTS---SVLVQWQP 1553
Query 354 LPPFEANGKILDYEVTLTR-----------------------------WKSHLQNYTVNA 384
NG +L Y + +K+ + +
Sbjct 1554 PKAESLNGLLLGYRIYYRELDYDAGSATESKAVKNPSALRAELTPQSSFKTVNSSSALTT 1613
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLKAFPKD-NMLWVE 442
+LT RY +T N++G+S + + + + +++ + L +
Sbjct 1614 YELTQLKKYKRYEVLMTAYNVIGESPTSTPVEVFVGEAAPAMAPQNIQVNSLSASQLELT 1673
Query 443 WTTPRESVKKY-ILEWCVLSDKAPCITDWQQEDGTVHRTYLRG--NLAESKCYLITVTPV 499
W P + I + + + D ++ L NL YL+ ++
Sbjct 1674 WDPPPADSQNGNIQGYKIYYWEGDVQNDTEKVKVFSSLRQLSASKNLTSHTRYLVCISAF 1733
Query 500 YADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
A G G QA PS + ++ + W + NG ++ Y + Y
Sbjct 1734 NAAGDGPRSRPSAGRTHQAAPSAPSFLVFSEITSTTLNVSWGE--PTAANGVLQGYRVVY 1791
Query 559 R---TIIGNETAVNVDSS---HTEYTLSSLTSDTLYMVRMAAYT---------------D 597
+ G V VD + LT Y+ R+ A T
Sbjct 1792 EPLAPVQGVSKVVTVDIKGNWQRWLKVRDLTKGMTYLFRVQARTIAYGPELQANVTAGPA 1851
Query 598 EGGKDGPEFTFTTPKFAQGEIEA 620
EG P T + ++
Sbjct 1852 EGSPGSPHEILVTKSASGLTVQW 1874
Score = 203 bits (516), Expect = 3e-52, Method: Composition-based stats.
Identities = 100/602 (17%), Positives = 194/602 (32%), Gaps = 48/602 (8%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
PE V C + + + IP+ + F
Sbjct 438 PEDTTVTEGMTAMLTCEVSGAPKPAISWKKGNQILASGSVQIPRFVLLESGGLQITPVFL 497
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITI----ISGLPPEKPKNLSCIVNEGKKMRCEWDG 148
A TC+ + +T+ PPE N + I +RC
Sbjct 498 QDAG---NYTCHAVNSEGALNAFVMLTVWNRTFIVHPPE---NSTVIKGTTATLRC---- 547
Query 149 GRETHLETNFTLKSEWATHKF---ADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
E + +++ W ++ T+ S + +I + + G
Sbjct 548 --EATHDPRISIRYVWKKDSVVINPSSSSRITVEKDGTLLISQTWSGDIGDYTCEVISFG 605
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD 265
S + + P+ P NL + S + L+W P + +L Y ++ +
Sbjct 606 GNDSRMARLEVIEL--PHSPQNLLATLNSSYSRSVVLSWVRPFDGNSPVLYYMVELSENN 663
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
+ ++ + +S TV L P Y FR+ + + GKG +S SE + + E+
Sbjct 664 SPW--KVHLSNLDPKMTSVTVSGLTPARTYQFRVCAVNQVGKGQYS--SETSRLMLPEEP 719
Query 326 PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT 385
PS P + + +++ + W+ P E NG + Y + + N T
Sbjct 720 PSAPPKN----IVASGRTNQSIMVQWQPPPESEHNGVLHGYILRYRLAGLPGEYQYKNIT 775
Query 386 KLTVN-------LTNDRYLATLTVRNLVGKSDAAV-LTIPACDFQATHPVMDLKAFP-KD 436
+N + +Y + N G + +T T P +++
Sbjct 776 SAEINYCLVTDLIIWTQYEIQVASYNGAGLGAFSRPVTEYTLQGVPTAPPQNVQVEAVNS 835
Query 437 NMLWVEWTTPRESVKKYI-LEWCVLSD--KAPCITDWQQEDGTVHRTYL--RGNLAESKC 491
+ W+ P + I + +L+ AP H + NL +
Sbjct 836 TTIQFLWSPPPQQFINGINQGYKLLAWPVDAPGSVTVVTIAPDFHGVHSGCITNLKKYTT 895
Query 492 YLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
Y +V G G + P + ++ + W + +NG
Sbjct 896 YYTSVLCFTTPGDGPRSAPQLLRTLEDKPGAVGHLSFTEILDTSLKVSWQE--PVEKNGI 953
Query 551 IRNYTIFYRTIIGNET--AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
I Y + + NE+ + ++ EY ++ L+S T Y + +AA T +G T
Sbjct 954 ITGYQLSWEVYGRNESRLTRTLTNTTLEYKITGLSSLTTYTIEVAAVTAKGSGWVTSSTI 1013
Query 609 TT 610
++
Sbjct 1014 SS 1015
Score = 198 bits (504), Expect = 1e-50, Method: Composition-based stats.
Identities = 101/510 (20%), Positives = 165/510 (32%), Gaps = 36/510 (7%)
Query 126 PEKPKNLSCIVNEGKKMRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P +LS ++ W + + + T + L E + T
Sbjct 924 PGAVGHLSFTEILDTSLKVSWQEPVEKNGIITGYQLSWEVYGRNESRLTRTLTNTTLEYK 983
Query 185 DYSTVYFVNIEVWVEAENALGK--VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
+ V A A G VTS I+ V P P NL + N L
Sbjct 984 ITGLSSLTTYTIEVAAVTAKGSGWVTSSTIS-SGVPPELPGAPSNLVISNI--SPRSATL 1040
Query 243 TWTNPSIKSVIILKYNIQYR---TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ I K+ ++ + + W + D V +L P+T Y FR+
Sbjct 1041 QFRPGYDGKTSICKWIVEGQVGVLGEEEEWVSLHEVDNEPDAQMLEVPNLTPYTHYRFRM 1100
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
R + G S S T + P AP T ++++ W LP +
Sbjct 1101 RQVNVVGASPLSQPS--RVIQTLQAPPDVAPGSVSV----RTASESSLRMRWVPLPDTQY 1154
Query 360 NGKI--LDYEVTLTRWKSHLQN-----YTVNATKLTVNLTN--DRYLATLTVRNLVGKSD 410
NG + Y + R + T+ Y + N +G
Sbjct 1155 NGNPESVGYRIKFWRVDLQPSALLKVISDRLERECTIQDLEEWTEYELQIQAFNAIGAGP 1214
Query 411 AA-VLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRES-VKKYILEWCVLS--DKAP 465
V+ + + + P ++ A + + W+ ES IL + +L
Sbjct 1215 WNEVVGVRTRESVPSAPPENVSAEAVSSTQILLTWSAVPESEQNGLILGYKILYKAKDLD 1274
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES--IKAYLKQAPPSKGP 523
Q G ++ L L + Y I V G G P S + K P
Sbjct 1275 SEPRSQTVRGNHTQSCLLSGLRKYVLYEIRVLAFTRIGDGVPSSPVLTERTKDDAPGPPI 1334
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYTLS 580
+ +V + W P + NG I Y I YR + T V V S+ ++T +
Sbjct 1335 RLVFPEVRLTSVRIVWQ--PPEEPNGIILGYQIAYRLASSSPNKFTTVEVGSTVRQFTAT 1392
Query 581 SLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
LT ++ Y+ R +A T +G + E T T
Sbjct 1393 DLTPESAYIFRTSAKTRQGWGEPLEATVIT 1422
Score = 175 bits (444), Expect = 2e-43, Method: Composition-based stats.
Identities = 95/553 (17%), Positives = 181/553 (33%), Gaps = 69/553 (12%)
Query 126 PEKPKNLSCIVNE--GKKMRCEWDGGRETHLETNF-TLKSEWATHKFADCKAKRDTP--T 180
P P+ L+ ++ + ++ W G + + T++ + + + T
Sbjct 1429 PAPPQQLTTPQSDVSSRSLQLHWVPGSDGSSPIRYFTVQVRELPNGDWQTYSSSISHEAT 1488
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKV--TSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
SC ++ F + ++ V+A N +G +++ + V PP ++ V + +S
Sbjct 1489 SCIIESLNP-FTSYKLRVKATNDIGDSDYSAETEAVTTLQDVPDEPPSSVLV--TPHTTS 1545
Query 239 ILKLTWTNPSIK--SVIILKYNIQYRT---------------------KDASTWSQIPPE 275
+ + W P + + ++L Y I YR + + S
Sbjct 1546 SVLVQWQPPKAESLNGLLLGYRIYYRELDYDAGSATESKAVKNPSALRAELTPQSSFKTV 1605
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
+++S +++ + LK + Y + G+ S S E P+ AP
Sbjct 1606 NSSSALTTYELTQLKKYKRYEVLMTAYNVIGE---SPTSTPVEVFVGEAAPAMAPQNIQV 1662
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV------ 389
S +Q ++L W P NG I Y++ W+ +QN T +
Sbjct 1663 NSLSASQ----LELTWDPPPADSQNGNIQGYKIYY--WEGDVQNDTEKVKVFSSLRQLSA 1716
Query 390 --NLTN-DRYLATLTVRNLVGKSDAAVLTI-PACDFQATHPVMDLKAFPKDNMLWVEWTT 445
NLT+ RYL ++ N G + + + P + + L V W
Sbjct 1717 SKNLTSHTRYLVCISAFNAAGDGPRSRPSAGRTHQAAPSAPSFLVFSEITSTTLNVSWGE 1776
Query 446 PRESVKKYILEWCVLSDKAPCITDWQQE-----DGTVHRTYLRGNLAESKCYLITVTPVY 500
P + + + V+ + + + G R +L + YL V
Sbjct 1777 PT-AANGVLQGYRVVYEPLAPVQGVSKVVTVDIKGNWQRWLKVRDLTKGMTYLFRVQART 1835
Query 501 ADGPGSPESIKAYLKQAPPSKG-PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
G A S G P + ++W + D Y I R
Sbjct 1836 IA-YGPELQANVTAGPAEGSPGSPHEILVTKSASGLTVQWTEG--DSGEKPTTGYIIEAR 1892
Query 560 TIIG---NETAVNVDSSHTEYTLS--SLTSDTLYMVRMAAYTDEGGKDG--PEFTFTTPK 612
+ ++ S T YT+S L Y R+ A + G + P +
Sbjct 1893 PSDEGLWDMFVKDIPRSATSYTVSLDKLKQGVTYEFRVVAVNEFGYGEPSVPSVAVSAQT 1952
Query 613 FAQGEIEAIVVPV 625
A E + V
Sbjct 1953 EAPFYEEWWFLLV 1965
Score = 119 bits (299), Expect = 4e-26, Method: Composition-based stats.
Identities = 75/434 (17%), Positives = 131/434 (30%), Gaps = 57/434 (13%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN---FTLKSEWATHKFADCKA 174
+T + +P E P ++ + + +W + L + + +
Sbjct 1523 VTTLQDVPDEPPSSVLVTPHTTSSVLVQWQPPKAESLNGLLLGYRIYYRELDYDAGSATE 1582
Query 175 KRDTPTSCTVDYSTV-----------------------YFVNIEVWVEAENALGKVT-SD 210
+ + + EV + A N +G+ S
Sbjct 1583 SKAVKNPSALRAELTPQSSFKTVNSSSALTTYELTQLKKYKRYEVLMTAYNVIGESPTST 1642
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP--SIKSVIILKYNIQYRTKDAST 268
+ P N+ V + +S L+LTW P ++ I Y I Y D
Sbjct 1643 PVEVFVGEAAPAMAPQNIQVNSL--SASQLELTWDPPPADSQNGNIQGYKIYYWEGDVQN 1700
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
++ + +S R ++L T Y+ I G G S S +G T++ PS
Sbjct 1701 DTE-KVKVFSSLRQLSASKNLTSHTRYLVCISAFNAAGDGPRSRPS---AGRTHQAAPS- 1755
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLT 388
APSF + + T T+ + W P ANG + Y V V +
Sbjct 1756 APSFLVFSEITST----TLNVSWGE--PTAANGVLQGYRVVYEPLAPVQGVSKVVTVDIK 1809
Query 389 VNLTND----------RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
N YL + R + + + ++ +
Sbjct 1810 GNWQRWLKVRDLTKGMTYLFRVQARTIAYGPELQANVTAGPAEGSPGSPHEILVTKSASG 1869
Query 439 LWVEWT---TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR-TYLRGNLAESKCYLI 494
L V+WT + + YI+E SD+ + + T L + Y
Sbjct 1870 LTVQWTEGDSGEKPTTGYIIE-ARPSDEGLWDMFVKDIPRSATSYTVSLDKLKQGVTYEF 1928
Query 495 TVTPVYADGPGSPE 508
V V G G P
Sbjct 1929 RVVAVNEFGYGEPS 1942
Score = 82.2 bits (201), Expect = 2e-14, Method: Composition-based stats.
Identities = 46/282 (16%), Positives = 77/282 (27%), Gaps = 19/282 (7%)
Query 52 EKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTC----NILT 107
++ I + E+ + + ++ S L C N
Sbjct 1678 PADSQNGNIQGYKIYYWEGDVQNDTEKVKVFSSLRQLSASKNLTSHTRYLVCISAFNAAG 1737
Query 108 FGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEW-DGGRETHLETNFTLKSE--- 163
G + G T + P P L + W + + + + E
Sbjct 1738 DGPRSRPSAGRTHQA--APSAPSFLVFSEITSTTLNVSWGEPTAANGVLQGYRVVYEPLA 1795
Query 164 --WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK 221
K K + V + V+A + +
Sbjct 1796 PVQGVSKVVTVDIKGNWQRWLKVR-DLTKGMTYLFRVQART---IAYGPELQANVTAGPA 1851
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P + I + +S L + WT Y I+ R D W +D +
Sbjct 1852 EGSPGSPHEILVTKSASGLTVQWTEGDSGEKPTTGYIIEARPSDEGLWDMF-VKDIPRSA 1910
Query 282 SSFTVQ--DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+S+TV LK Y FR+ + E G G S S S T
Sbjct 1911 TSYTVSLDKLKQGVTYEFRVVAVNEFGYGEPSVPSVAVSAQT 1952
>sp|Q07409|CNTN3_MOUSE Contactin-3 OS=Mus musculus OX=10090 GN=Cntn3
PE=1 SV=2
Length=1028
Score = 289 bits (738), Expect = 8e-82, Method: Composition-based stats.
Identities = 124/628 (20%), Positives = 215/628 (34%), Gaps = 50/628 (8%)
Query 38 VQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASL 97
VQ+ S C + + + + +EQ + + ++
Sbjct 421 VQVGSLVILDC--------KPRASPRALSFWKKGDMMVREQARVSFLNDGGLKIMNVTKA 472
Query 98 NIQ-LTCNILT-FGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE 155
+ TC FG+ + + P N+ V E + C+ + L+
Sbjct 473 DAGTYTCTAENQFGKANGTTHLVVTEPTRIILAPSNMDVAVGESVILPCQVQ--HDPLLD 530
Query 156 TNFTLKSEWATHKFA-DCKAKRDTPTSCTVDY---STVYFVNIEVWVEAENALGKVTSDH 211
F A F D S + D + + + + + V+S
Sbjct 531 IMFAWYFNGALTDFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSS-- 588
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQ 271
+ + + P PP N+ V E + +L+WT + ++ Y +Q RT + W
Sbjct 589 -AAELIVRGSPGPPENVKVD--EITDTTAQLSWTEGTDSHSPVISYAVQARTPFSVGWQS 645
Query 272 IP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
+ PE + TV +L P+ EY FRI + G G S SE+ T E P A
Sbjct 646 VRTVPEVIDGKTHTATVVELNPWVEYEFRIVASNKIGGGEPSLPSEKVR--TEEAAPEIA 703
Query 330 PSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTR-----WKSHLQNYTVN 383
PS + S G R+ + + W +P NG Y V W + N
Sbjct 704 PS-----EVSGGGGSRSELVITWDPVPEELQNGGGFGYVVAFRPLGVTTWIQTVVTSPDN 758
Query 384 ATKLTVN---LTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLKAFP-KDNM 438
+ N + Y + V N G+ + V T+ + + + T + A +
Sbjct 759 PRYVFRNESIVPFSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSHISAHSLSSSE 818
Query 439 LWVEWTT-PRESVKKYILEWCVLSD---KAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
+ V W T P + ++L + V + + G LRG L + Y
Sbjct 819 IEVSWNTIPWKLSNGHLLGYEVRYWNNGGEEESSRKVKVAGNQTSAVLRG-LKSNLAYYT 877
Query 495 TVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
V + G G ++ A K+ PPS+ P + +L W+Q+ +
Sbjct 878 AVRAYNSAGAGPFSATVNATTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTG 937
Query 554 YTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKF 613
Y +FYRT N V + + L + D Y++ + A TD GG P+
Sbjct 938 YKVFYRTSSQNNVHVLNTNKTSAELLLPIKED--YIIEVKATTD-GGDGTSSEQIRIPRI 994
Query 614 AQGEIEAIVVPVCLAFLLTTLLGVLFCF 641
+ + L+ + VL F
Sbjct 995 TSMDARGSTSAISNIHPLSGYMSVLLFF 1022
Score = 139 bits (351), Expect = 2e-32, Method: Composition-based stats.
Identities = 81/508 (16%), Positives = 163/508 (32%), Gaps = 51/508 (10%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFT--IPKEQYTIINRTASS 88
++P + V + + C ++ + W N K+ SS
Sbjct 504 LAPSNMDVAVGESVILPCQVQHDPLLDIMFA-----WYFNGALTDFKKDGSHFEKVGGSS 558
Query 89 VTFTDIASLNIQLTCNILTFGQLEQNVY--GITIISGLPPEKPKNLSCIVNEGKKMRCEW 146
I ++ ++ + + Q + +I P P+N+ + W
Sbjct 559 SGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAAELIVRGSPGPPENVKVDEITDTTAQLSW 618
Query 147 DGGRETHLET-NFTLKSE------WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
G ++H ++ +++ W + + T T+ V+ + +V E +
Sbjct 619 TEGTDSHSPVISYAVQARTPFSVGWQSVRTVPEVIDGKTHTATVVELNP--WVEYEFRIV 676
Query 200 AENALGKV-TSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTN--PSIKSVIIL 255
A N +G S + P P V S L +TW +++
Sbjct 677 ASNKIGGGEPSLPSEKVRTEEAAPEIAPS--EVSGGGGSRSELVITWDPVPEELQNGGGF 734
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y + +R +TW Q + R F + + PF+ Y ++ G+G + S
Sbjct 735 GYVVAFRPLGVTTWIQTVVTSPDNPRYVFRNESIVPFSPYEVKVGVYNNKGEGPF---SP 791
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
+ + E+ P+ APS +H+ +++ W T+P +NG +L YEV
Sbjct 792 VTTVFSAEEEPTVAPSH----ISAHSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNNGG 847
Query 376 HLQNY-----TVNATKLTVNLTND--RYLATLTVRNLVGKSD-AAVLTIPACDFQATHPV 427
++ N T + Y + N G +A + + P
Sbjct 848 EEESSRKVKVAGNQTSAVLRGLKSNLAYYTAVRAYNSAGAGPFSATVNATTKKTPPSQPP 907
Query 428 MDLKAFPKDNMLWVEWTTPRES-----VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
++ D + + W + V Y + + S + + L
Sbjct 908 GNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQN-----NVHVLNTNKTSAEL 962
Query 483 RGNLAESKCYLITVTPVYADGPGSPESI 510
+ E Y+I V G G+
Sbjct 963 LLPIKED--YIIEVKATTDGGDGTSSEQ 988
>sp|Q3UH53|SDK1_MOUSE Protein sidekick-1 OS=Mus musculus OX=10090
GN=Sdk1 PE=1 SV=1
Length=2193
Score = 293 bits (749), Expect = 1e-81, Method: Composition-based stats.
Identities = 124/581 (21%), Positives = 212/581 (36%), Gaps = 63/581 (11%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRET---HLETNF-T 159
N + G + V G T S +P P+N+S ++ W E L +
Sbjct 1238 NAIGAGPWSELVRGRTRES-VPSAAPENVSAEAVSSTQILLTWASVPEQDQNGLILGYKV 1296
Query 160 LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK-VTSDHINFDPVY 218
L R T + FV E+ V A +G V S + +
Sbjct 1297 LYCAKDLDPEPRSHVVRGNHTQSALLAGLRKFVVYELQVLAFTRIGNGVPSSPLILERTK 1356
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
P PP + ++ E + +++ W P + +IL Y I YR S + E
Sbjct 1357 DDTPGPP--VRLVFPEVRLTAVRIVWQPPEEPNGVILGYQIAYRLASGSPHTFTTVE-VG 1413
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+T FT +L P + Y+FR+ G W + E A+ IT E R AP + P
Sbjct 1414 ATVRQFTATELAPESAYIFRLSAKTRQG---WGEPLE-ATVITTEKRERPAPPRELLV-P 1468
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR-----WKSHLQNYTVNATKLTVNLTN 393
R+++L W +P + I + V + W+++ + + AT V
Sbjct 1469 QAEVTARSLRLQW--VPGSDGASPIRYFTVQVRELPGGEWQTYSSSISHEATACAVERLR 1526
Query 394 --DRYLATLTVRNLVGKSDAAVLTIPACDFQ--ATHPVMDLKAFPKD-NMLWVEWTTPR- 447
Y L N +G SD + T Q P + A P + + ++W PR
Sbjct 1527 PFTSYKLRLKATNDIGDSDFSAETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRD 1586
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHR------------------------TYLR 483
ES+ + + + + T E T+ TY
Sbjct 1587 ESLNGLLQGYRIYYRELESETGMSPEPKTLKSPSALRAELTAQSSFKTVNSSSSLTTYEL 1646
Query 484 GNLAESKCYLITVTPVYADGPGSPE-SIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQ 541
+L + + Y + +T G ++ ++ +A P+ P V+ + ++ + WD
Sbjct 1647 THLKKYRRYEVIMTAYNIIGESPASVPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDP 1706
Query 542 LPVDVQNGFIRNYTIFYRTIIGNETAVN---VDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
P + QNG I+ Y ++Y + + LTS T Y++ ++A+
Sbjct 1707 PPPESQNGNIQGYKVYYWEADSRNETEKMKVLFLPEPVVKIKDLTSHTKYLISISAFNAA 1766
Query 599 GGKDGPEFTFTTPKFAQGEIEAIVVPVCLAF--LLTTLLGV 637
G DGP+ + P + A P LAF + +T L V
Sbjct 1767 G--DGPK---SDPCQGRTHQAAPGPPSFLAFSEITSTTLNV 1802
Score = 210 bits (534), Expect = 2e-54, Method: Composition-based stats.
Identities = 82/419 (20%), Positives = 151/419 (36%), Gaps = 27/419 (6%)
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST 268
SD P+PP NL S S + L+W P + +L Y +Q ++
Sbjct 637 SDSRTARLEVIELPHPPQNLLASLSPARSHSVTLSWVRPFDGNSPVLYYIVQVSENNSPW 696
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
++ + + TV L P Y FR+ + + GKG +S E + + E+ PS
Sbjct 697 --KVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNQVGKGQYST--ETSRLMLPEEPPSA 752
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLT 388
P + + +++ + W+ P E NG + Y + ++ N +
Sbjct 753 PPKN----IVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEHQQRNISSPE 808
Query 389 VN-------LTNDRYLATLTVRNLVGKSDAAV-LTIPACDFQATHPVMDLKAFP-KDNML 439
VN + +Y + N G + +T T P +++A +
Sbjct 809 VNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQAEAVNSTTV 868
Query 440 WVEWTTPRESVKKYI-LEWCVLSD--KAPCITDWQQEDGTVHRTY--LRGNLAESKCYLI 494
W P + I + +L+ AP H + NL + Y
Sbjct 869 HFLWNPPPQQFINGINQGYKLLAWPADAPETVTVVTIAPDFHGIHHGYITNLKKFTAYFT 928
Query 495 TVTPVYADGPGSPESIK-AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
+V G G P S + + + P + ++ + W + +NG I
Sbjct 929 SVLCFTTPGDGPPSSPQLVWTHEDKPGAVGHLSFTEILDTSLKVSWQE--PLERNGIIMG 986
Query 554 YTIFYRTIIGNETAV--NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
Y I + N++ + ++S+ EY + L+S T Y + +AA T G T ++
Sbjct 987 YQISWEVYGRNDSRLTHTLNSTMHEYKIQGLSSLTTYTIDVAALTAAGVGVTTSSTISS 1045
Score = 181 bits (460), Expect = 2e-45, Method: Composition-based stats.
Identities = 96/551 (17%), Positives = 175/551 (32%), Gaps = 65/551 (12%)
Query 126 PEKPKNLSCIVNEGK--KMRCEWDGGRETHLETNF-TLKSEWATHKFADCKAKRDTPTSC 182
P P+ L E +R +W G + + T++ + + +
Sbjct 1459 PAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTVQVRELPGGEWQTYSSSISHEAT 1518
Query 183 TVDYSTVY-FVNIEVWVEAENALGKV--TSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ F + ++ ++A N +G +++ + V PP SV + +S
Sbjct 1519 ACAVERLRPFTSYKLRLKATNDIGDSDFSAETEAVTTLQDVPGEPPG--SVSATPHTTSS 1576
Query 240 LKLTWTNPSIK--SVIILKYNIQYRTKDAST---------------------WSQIPPED 276
+ + W P + + ++ Y I YR ++ T S +
Sbjct 1577 VLIQWQPPRDESLNGLLQGYRIYYRELESETGMSPEPKTLKSPSALRAELTAQSSFKTVN 1636
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
++S+ +++ + LK + Y + G+ S S E P+ AP
Sbjct 1637 SSSSLTTYELTHLKKYRRYEVIMTAYNIIGE---SPASVPVEVFVGEAAPAMAPQNVQVT 1693
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN-------YTVNATKLTV 389
+ +Q +++ W PP NG I Y+V S + K+
Sbjct 1694 PLTASQ----LEVTWDPPPPESQNGNIQGYKVYYWEADSRNETEKMKVLFLPEPVVKIKD 1749
Query 390 NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK-AFPKDNMLWVEWTTPR- 447
++ +YL +++ N G + A P L + L V W P
Sbjct 1750 LTSHTKYLISISAFNAAGDGPKSDPCQGRTHQAAPGPPSFLAFSEITSTTLNVSWGEPSA 1809
Query 448 --ESVKKYILEWCVLSDKAPCITDWQQ-EDGTVHRTYLRGNLAESKCYLITVTPVY-ADG 503
++ Y + + L+ G R +L + Y V A G
Sbjct 1810 ANGILQGYRVVYEPLAPVQGVSKVVTVDVKGNWQRWLKVRDLTKGVTYFFRVQARTIAYG 1869
Query 504 PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG--FIRNYTIFYRTI 561
P ++ A + P V K +E L+W + G Y I R
Sbjct 1870 PELQANVTAGPAEGSPGSPRNVLVTK-SASELTLQW----TEGNAGTTPTTGYVIEARPS 1924
Query 562 IG---NETAVNVDSSHTEYT--LSSLTSDTLYMVRMAAYTDEG-GKDG-PEFTFTTPKFA 614
+ A ++ S T YT L L Y R+ A G G+ P + A
Sbjct 1925 DEGLWDMFAKDIPRSATSYTVDLDKLRQGVTYEFRVVAVNKAGFGEPSRPSIAVSAQAEA 1984
Query 615 QGEIEAIVVPV 625
E + V
Sbjct 1985 PFYEEWWFLLV 1995
Score = 181 bits (459), Expect = 3e-45, Method: Composition-based stats.
Identities = 111/608 (18%), Positives = 193/608 (32%), Gaps = 59/608 (10%)
Query 52 EKCMDYFHVNANYIVWKTNHFTIP-----KEQYTIINR------TASSVTF-TDIASLNI 99
+ + VN+ + + N + Y ++ T + VT D ++
Sbjct 855 PQNVQAEAVNSTTVHFLWNPPPQQFINGINQGYKLLAWPADAPETVTVVTIAPDFHGIHH 914
Query 100 QLTCNILTFGQLEQNVYGITIISGLPPEKPK-------------NLSCIVNEGKKMRCEW 146
N+ F +V T PP P+ +LS ++ W
Sbjct 915 GYITNLKKFTAYFTSVLCFTTPGDGPPSSPQLVWTHEDKPGAVGHLSFTEILDTSLKVSW 974
Query 147 -DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
+ + + + E + ++ + V A A G
Sbjct 975 QEPLERNGIIMGYQISWEVYGRNDSRLTHTLNSTMHEYKIQGLSSLTTYTIDVAALTAAG 1034
Query 206 K-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK 264
VT+ V P P NL + N L + I ++ ++ +
Sbjct 1035 VGVTTSSTISSGVPPDLPGAPSNLVISNI--SPRSATLQFRPGYDGKTAICRWIVEGQVG 1092
Query 265 ---DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
D W + E+ + +L P+T Y FR+R + G +S S T
Sbjct 1093 AIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMRQVNIVGPSPFSQSS--RVIQT 1150
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI--LDYEVTLTRWKSHLQN 379
+ P AP+ T +++L W LP + NG + Y V R
Sbjct 1151 LQAPPDVAPTSLTV----RTASETSLRLRWVPLPDSQYNGNPESVGYRVKYWRSDQPSSA 1206
Query 380 -YTVNATKLTVNLT------NDRYLATLTVRNLVGKSDAAVLTI-PACDFQATHPVMDLK 431
V + +L LT Y + N +G + L + + ++
Sbjct 1207 LAQVVSDRLERELTIEELEEWTEYELRMQAFNAIGAGPWSELVRGRTRESVPSAAPENVS 1266
Query 432 AFP-KDNMLWVEWTTPRE-SVKKYILEWCVLS--DKAPCITDWQQEDGTVHRTYLRGNLA 487
A + + W + E IL + VL G ++ L L
Sbjct 1267 AEAVSSTQILLTWASVPEQDQNGLILGYKVLYCAKDLDPEPRSHVVRGNHTQSALLAGLR 1326
Query 488 ESKCYLITVTPVYADGPGSPES--IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
+ Y + V G G P S I K P + +V + W P +
Sbjct 1327 KFVVYELQVLAFTRIGNGVPSSPLILERTKDDTPGPPVRLVFPEVRLTAVRIVWQ--PPE 1384
Query 546 VQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
NG I Y I YR G+ T V V ++ ++T + L ++ Y+ R++A T +G +
Sbjct 1385 EPNGVILGYQIAYRLASGSPHTFTTVEVGATVRQFTATELAPESAYIFRLSAKTRQGWGE 1444
Query 603 GPEFTFTT 610
E T T
Sbjct 1445 PLEATVIT 1452
Score = 176 bits (447), Expect = 9e-44, Method: Composition-based stats.
Identities = 109/655 (17%), Positives = 192/655 (29%), Gaps = 65/655 (10%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
PE VV + T C + Y+ K N I+ S+ +
Sbjct 562 PEDRVVIKGTTATLCC----GATHDPRTSLRYVWKKDNVVITASSSSRIVVEKDGSLVIS 617
Query 93 DIASLNIQ-LTCNILTFGQLEQNVYGITIISGLPPEKPKNL--SCIVNEGKKMRCEWDGG 149
S +I TC I++ G + + P P+NL S + W
Sbjct 618 QTWSGDIGDYTCEIISEGGSDSRT--ARLEVIELPHPPQNLLASLSPARSHSVTLSWVRP 675
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSC-TVDYSTVYFVNIEVWVEAENALGKVT 208
+ + + + + P + V A N +GK
Sbjct 676 FDGNSPVLYYIVQVSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNQVGKGQ 735
Query 209 -SDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIK--SVIILKYNIQYRTK 264
S + + + P+ PP N+ + S + + + W P + ++ Y ++YR
Sbjct 736 YSTETSRLMLPEEPPSAPPKNI--VASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLA 793
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
Q + V DL +T+Y ++ G G +S E T +
Sbjct 794 GLPGEHQQRNISSPEVNY-CLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEY---TLQG 849
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN- 383
P+ P + TV +W P NG Y++ + V
Sbjct 850 VPTAPPQNV----QAEAVNSTTVHFLWNPPPQQFINGINQGYKLLAWPADAPETVTVVTI 905
Query 384 -------ATKLTVNLTN-DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK-AFP 434
NL Y ++ G + + V L
Sbjct 906 APDFHGIHHGYITNLKKFTAYFTSVLCFTTPGDGPPSSPQLVWTHEDKPGAVGHLSFTEI 965
Query 435 KDNMLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
D L V W P E + Y + W V +T + T+H ++G L+
Sbjct 966 LDTSLKVSWQEPLERNGIIMGYQISWEVYGRNDSRLT--HTLNSTMHEYKIQG-LSSLTT 1022
Query 492 YLITVTPVYADGPG--SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y I V + A G G + +I + + P + + A L++ P
Sbjct 1023 YTIDVAALTAAGVGVTTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFR--PGYDGKT 1080
Query 550 FIRNYTIFYRTIIGNETAVNVDSSHTE-------YTLSSLTSDTLYMVRMAAYTDEGGKD 602
I + + + + V E + +LT T Y RM G
Sbjct 1081 AICRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMRQVNIVGPSP 1140
Query 603 GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPD 657
+ + I+ + P +A T+ + + W +PD
Sbjct 1141 FSQSSRV--------IQTLQAPPDVAPTSLTVRT------ASETSLRLRWVPLPD 1181
Score = 126 bits (316), Expect = 4e-28, Method: Composition-based stats.
Identities = 75/460 (16%), Positives = 136/460 (30%), Gaps = 57/460 (12%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE---TNFTL 160
N + +T + +P E P ++S + + +W R+ L + +
Sbjct 1539 NDIGDSDFSAETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRI 1598
Query 161 KSEWATHKF----------------ADCKAKRDTPTSCTVDYSTVYFVN-------IEVW 197
+ A+ A+ T + T Y + EV
Sbjct 1599 YYRELESETGMSPEPKTLKSPSALRAELTAQSSFKTVNSSSSLTTYELTHLKKYRRYEVI 1658
Query 198 VEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK--SVII 254
+ A N +G+ S + P N+ V + +S L++TW P + + I
Sbjct 1659 MTAYNIIGESPASVPVEVFVGEAAPAMAPQNVQV--TPLTASQLEVTWDPPPPESQNGNI 1716
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
Y + Y D+ ++ + ++DL T+Y+ I G G SD
Sbjct 1717 QGYKVYYWEADSRNETE-KMKVLFLPEPVVKIKDLTSHTKYLISISAFNAAGDGPKSDPC 1775
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK 374
+ G T++ P PSF + + T T+ + W P ANG + Y V
Sbjct 1776 Q---GRTHQAAP-GPPSFLAFSEITST----TLNVSWGE--PSAANGILQGYRVVYEPLA 1825
Query 375 SHLQNYTVNATKLTVNLTND----------RYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
V + N Y + R + + +
Sbjct 1826 PVQGVSKVVTVDVKGNWQRWLKVRDLTKGVTYFFRVQARTIAYGPELQANVTAGPAEGSP 1885
Query 425 HPVMDLKAFPKDNMLWVEW---TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
++ + L ++W Y++E + + T
Sbjct 1886 GSPRNVLVTKSASELTLQWTEGNAGTTPTTGYVIEARPSDEGLWDMFAKDIPRSATSYTV 1945
Query 482 LRGNLAESKCYLITVTPVYADGPGSPE--SIKAYLKQAPP 519
L + Y V V G G P SI + P
Sbjct 1946 DLDKLRQGVTYEFRVVAVNKAGFGEPSRPSIAVSAQAEAP 1985
>sp|Q8AV57|SDK2_CHICK Protein sidekick-2 OS=Gallus gallus OX=9031
GN=SDK2 PE=1 SV=2
Length=2177
Score = 291 bits (744), Expect = 6e-81, Method: Composition-based stats.
Identities = 132/619 (21%), Positives = 210/619 (34%), Gaps = 70/619 (11%)
Query 79 YTIINRTASSVTFTDI---ASLNIQLTC-NILTFGQLEQNVYGITIISGLPPEKPKNLSC 134
+ I +R T D+ +Q+ N + G V G T S +P P N+S
Sbjct 1155 HVIHDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSHLVLGRTRES-VPSSGPSNVSA 1213
Query 135 IVNEGKKMRCEWD-------GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
M W G + F K A +F + T
Sbjct 1214 QATSSSNMLVRWSDIPEADCNGLILGYKVMFKEKDSEARAQFWLAEGNTSRSAQLTGLGK 1273
Query 188 TVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
F+ E+ V A +G V S + P PP + ++ E ++ ++L W
Sbjct 1274 ---FMLYEIRVLAFTRIGDGVPSRPPILERTLDDVPGPP--VGMLFPEVRTTSVRLIWQP 1328
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P+ + IIL Y + +R + + + E + +T L+P Y+F I G
Sbjct 1329 PTAPNGIILAYQLTHRLNTTTANAAVS-EVLGPSTRQYTATGLQPEATYLFSITAQTRKG 1387
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
G + EA +T E R P + + R+V L W+ P + + Y
Sbjct 1388 WGE----AAEALVVTTEKRDRPQPPSKPLVRQEDVRA-RSVLLSWE--PGSDGLSPVRFY 1440
Query 367 EVTLTR-----WKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPAC 419
V W H + + NAT V+ Y + N +G S+ + +
Sbjct 1441 TVQTRELPSGEWALHPASISHNATAFVVDRLKPFTSYKFRVKATNDIGDSEYSEESESLT 1500
Query 420 DFQATH--PVMDLKAFPKDN-MLWVEWTTPRESVKKYIL-----EWCVL-SDKAPCIT-- 468
QA L P + + W P E IL + L D T
Sbjct 1501 TLQAAPEEAPTILSVTPHTTTSVLIRWQPPSEDKINGILLGFRLRYRELLYDSLRGFTLH 1560
Query 469 -------DW---------QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-IK 511
W Y NL++ + Y I ++ A G G P +
Sbjct 1561 GIGNPGATWAELTPVYAVHNLSEVSLTQYELDNLSKHRRYEIRMSVYNAVGEGPPSPPQE 1620
Query 512 AYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
++ +A P+ P V K + + W+ P + QNG I+ Y I + + V
Sbjct 1621 VFVGEAMPTGAPQNVAVKAATATQLDVTWEPPPTESQNGDIQGYKIHFWEAQRQNESARV 1680
Query 571 DS---SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
+ T L +LT T Y V +AA+ G DGP +TP A+ + A P +
Sbjct 1681 KTLFLPETGVKLKNLTGYTSYWVSIAAFNAAG--DGPR---STPVTARTQQAAPSAPGSI 1735
Query 628 AFLLTTLLGVLFCFNKRDL 646
F T V + L
Sbjct 1736 RFSELTTTSVNVSWEPPPL 1754
Score = 199 bits (506), Expect = 5e-51, Method: Composition-based stats.
Identities = 99/527 (19%), Positives = 169/527 (32%), Gaps = 60/527 (11%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGR-ETHLETNFTLKSEWATHKFADCKAKRDTP-T 180
P P + +R W + + L T ++ P T
Sbjct 1303 DDVPGPPVGMLFPEVRTTSVRLIWQPPTAPNGIILAYQLTHRLNTTTANAAVSEVLGPST 1362
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTS-DHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ A+ G + + + + +P PP V + +
Sbjct 1363 RQYTATGLQPEATYLFSITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPLVRQEDVRARS 1422
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L+W S + Y +Q R + W + P + ++F V LKPFT Y FR+
Sbjct 1423 VLLSWEPGSDGLSPVRFYTVQTRELPSGEW-ALHPASISHNATAFVVDRLKPFTSYKFRV 1481
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
+ + G +S+ E S T + P +AP+ + P T +V + W+ +
Sbjct 1482 KATNDIGDSEYSE--ESESLTTLQAAPEEAPTI-LSVTPHTTT---SVLIRWQPPSEDKI 1535
Query 360 NGKILDYEVTLTR--------------------WKSHLQNYTVNA------TKLTVNLTN 393
NG +L + + W Y V+ T+ ++ +
Sbjct 1536 NGILLGFRLRYRELLYDSLRGFTLHGIGNPGATWAELTPVYAVHNLSEVSLTQYELDNLS 1595
Query 394 D--RYLATLTVRNLVGKSDAAV--LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR-E 448
RY ++V N VG+ + P L V W P E
Sbjct 1596 KHRRYEIRMSVYNAVGEGPPSPPQEVFVGEAMPTGAPQNVAVKAATATQLDVTWEPPPTE 1655
Query 449 SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG------NLAESKCYLITVTPVYAD 502
S I + + +A Q E V +L NL Y +++ A
Sbjct 1656 SQNGDIQGYKIHFWEAQR----QNESARVKTLFLPETGVKLKNLTGYTSYWVSIAAFNAA 1711
Query 503 GPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR-- 559
G G + A +QA PS ++R ++ + W+ P+ NG + Y + Y
Sbjct 1712 GDGPRSTPVTARTQQAAPSAPGSIRFSELTTTSVNVSWEPPPL--PNGILEGYRLVYEPC 1769
Query 560 -TIIGNETAVNVDSSHTE---YTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ G V VD + L Y R+ A T G D
Sbjct 1770 MPVDGVSKIVTVDVKGNSPLWMKVKDLAEGITYRFRIRAKTFAYGPD 1816
Score = 188 bits (476), Expect = 2e-47, Method: Composition-based stats.
Identities = 112/781 (14%), Positives = 238/781 (30%), Gaps = 78/781 (10%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P+ V + C + + +P+ +T++ + V+
Sbjct 413 PQDSTVIDGMSVILNCETSGAPRPAITWQKGERILASGSVQLPR--FTLLESGSLLVSPA 470
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRET 152
+ + G E + + + P++ S I M C
Sbjct 471 HLTDAGTYTCLATNSRGVDEASADLVVWARTRITDPPQDQSVIKGTKASMSC------GV 524
Query 153 HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENA----LGKVT 208
+ + ++ W ++ +D + ++ + L
Sbjct 525 THDPSVDVRYIWEKDGAP---LGTESGPRLRLDETGTLHISQTWSGDIGTYTCKVLSAGG 581
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST 268
+D + + P+ P + + S + LTW P + +L+Y ++ +A
Sbjct 582 NDSRSAHLRVRQLPHAPESPVAVLSPLEKRAINLTWAKPFDGNSPLLRYLVEISENNAPW 641
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
+ + V+ L P Y FR+ + + G+ +S +E S E+ P
Sbjct 642 --TVLLASVDPELTWVVVRGLVPARSYQFRLCAVNDVGRSQFSKDTERVSL--PEEPPFA 697
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLT 388
P + + +++ + W+ P NG + Y + + N T
Sbjct 698 PPQNVI----ASGRTNQSIMIQWQPPPESHQNGVLKGYIIRYCLAGLPVGYQFKNITNAD 753
Query 389 VNLTN-------DRYLATLTVRNLVGKSDAAVLTIPACDFQA---THPVMDLKAFPKDNM 438
VN Y + N G + + Q P
Sbjct 754 VNNLLLEDLIIWTNYEIEVAAYNSAGLG-VYSMKVTEWTLQGVPTVPPGNVQTEATNSTT 812
Query 439 LWVEWTTPRESVKKYI------LEWCVLSDKAPCITDWQ-QEDGTVHRTYLRGNLAESKC 491
+ W P I + W ++ + + +VH Y+ G L +
Sbjct 813 IRFTWNPPSPQFINGINQGYKLIAWEPEHEEEATVVTVRPNFQDSVHVGYVVG-LKKFTE 871
Query 492 YLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
YL +V G G + P + ++ + W + +NG
Sbjct 872 YLTSVLCFTTPGDGPRSPPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQE--PLEKNGI 929
Query 551 IRNYTIFYRTIIGNETAVN--VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
+ Y I + T V + + EY ++ LT+ T Y + +AA T +G T
Sbjct 930 LTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSSSTI 989
Query 609 TTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSP 668
+ + E P L V F + K+ I++W
Sbjct 990 S----SGVPPELPGAPTNLGISNIGPRSVTLQFR-------PGYD-----GKTSISRWQV 1033
Query 669 HTPPRHNFNSKDQ--MYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSS 726
N +++ ++ N D +E+ + + F+ ++N G S
Sbjct 1034 EAQVGQNGEAEEWGLVHQLANEPDARSLEVPNLNP-------YTYYSFRMRQVNIVGTSP 1086
Query 727 GIGGSSCMSS--SRPSISSSDEN-ESSQNTSSTVQYSTVVHSGYRHQVPSVQV---FSRS 780
S + + + P ++ ++ ++ TS +++ ++ Y SV + RS
Sbjct 1087 PSLPSRRIQTLQAPPDVAPANVTLRTASETSLWLRWMPLLEQEYNGNPDSVGYRIRYLRS 1146
Query 781 E 781
+
Sbjct 1147 D 1147
Score = 183 bits (465), Expect = 6e-46, Method: Composition-based stats.
Identities = 92/511 (18%), Positives = 153/511 (30%), Gaps = 36/511 (7%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P +LS ++ W + + + T + + E T
Sbjct 899 VPGPVGHLSFSEILDTSLKVSWQEPLEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEY 958
Query 184 VDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
+ V A + G+ S V P P NL + N + L
Sbjct 959 RVTGLTALTTYTIEVAAMTSKGQGQVSSSTISSGVPPELPGAPTNLGISNIG--PRSVTL 1016
Query 243 TWTNPSIKSVIILKYNIQYR---TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ I ++ ++ + +A W + S V +L P+T Y FR+
Sbjct 1017 QFRPGYDGKTSISRWQVEAQVGQNGEAEEWGLVHQLANEPDARSLEVPNLNPYTYYSFRM 1076
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
R + G S S T + P AP+ T ++ L W L E
Sbjct 1077 RQVNIVGTSPPSLPS--RRIQTLQAPPDVAPANVTL----RTASETSLWLRWMPLLEQEY 1130
Query 360 NGKI--LDYEVTLTRWKSHLQNYTVNAT-----KLTVNLTN--DRYLATLTVRNLVGKSD 410
NG + Y + R + + T+ Y + N +G
Sbjct 1131 NGNPDSVGYRIRYLRSDGQGRAVVHVIHDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGP 1190
Query 411 AAVLTI-PACDFQATHPVMDLKAFPKDNM-LWVEW-TTPRESVKKYILEWCVL---SDKA 464
+ L + + + ++ A + + V W P IL + V+ D
Sbjct 1191 WSHLVLGRTRESVPSSGPSNVSAQATSSSNMLVRWSDIPEADCNGLILGYKVMFKEKDSE 1250
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE--SIKAYLKQAPPSKG 522
W E G R+ L + Y I V G G P I P
Sbjct 1251 ARAQFWLAE-GNTSRSAQLTGLGKFMLYEIRVLAFTRIGDGVPSRPPILERTLDDVPGPP 1309
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR---TIIGNETAVNVDSSHTEYTL 579
+ +V L W P NG I Y + +R T + + S +YT
Sbjct 1310 VGMLFPEVRTTSVRLIWQ--PPTAPNGIILAYQLTHRLNTTTANAAVSEVLGPSTRQYTA 1367
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ L + Y+ + A T +G + E T
Sbjct 1368 TGLQPEATYLFSITAQTRKGWGEAAEALVVT 1398
Score = 176 bits (447), Expect = 1e-43, Method: Composition-based stats.
Identities = 103/552 (19%), Positives = 177/552 (32%), Gaps = 63/552 (11%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRET---HLETNFTLKSEWATHKFADC--KAKRD 177
G+P P N+ +R W+ + + L + H+ + +
Sbjct 794 GVPTVPPGNVQTEATNSTTIRFTWNPPSPQFINGINQGYKLIAWEPEHEEEATVVTVRPN 853
Query 178 TPTSCTVDY--STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
S V Y F V G ++ P P +LS SE
Sbjct 854 FQDSVHVGYVVGLKKFTEYLTSVLCFTTPGDGPRSPPQLVRTHEDVPGPVGHLS--FSEI 911
Query 236 LSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
L + LK++W P K+ I+ Y I + + + + + + V L T Y
Sbjct 912 LDTSLKVSWQEPLEKNGILTGYRISWEEYNRT--NTRVTHYLPNVTLEYRVTGLTALTTY 969
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
+ M G+G S S +SG+ E AP+ + G R+V L + P
Sbjct 970 TIEVAAMTSKGQGQVSS-STISSGVPPELP--GAPTNLGISN----IGPRSVTL--QFRP 1020
Query 356 PFEANGKILDYEVTLTRWKS---------HLQNYTVNATKLTVNLTN--DRYLATLTVRN 404
++ I ++V ++ H +A L V N Y + N
Sbjct 1021 GYDGKTSISRWQVEAQVGQNGEAEEWGLVHQLANEPDARSLEVPNLNPYTYYSFRMRQVN 1080
Query 405 LVGKSDAAVLTIPACDFQATH---PVMDLKAFPKDNMLWVEWTTPRE-------SVKKYI 454
+VG S ++ + QA P + LW+ W E Y
Sbjct 1081 IVGTSPPSLPSRRIQTLQAPPDVAPANVTLRTASETSLWLRWMPLLEQEYNGNPDSVGYR 1140
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAY 513
+ + + + + V R Y +L E Y + V A G G +
Sbjct 1141 IRYLRSDGQGRAVVHVIHD--RVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSHLVLGR 1198
Query 514 LKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA---VN 569
+++ PS GP V + + ++ W +P NG I Y + ++ A +
Sbjct 1199 TRESVPSSGPSNVSAQATSSSNMLVRWSDIPEADCNGLILGYKVMFKEKDSEARAQFWLA 1258
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK---------------DGPEFTFTTPKFA 614
++ L+ L LY +R+ A+T G GP P+
Sbjct 1259 EGNTSRSAQLTGLGKFMLYEIRVLAFTRIGDGVPSRPPILERTLDDVPGPPVGMLFPEVR 1318
Query 615 QGEIEAIVVPVC 626
+ I P
Sbjct 1319 TTSVRLIWQPPT 1330
Score = 176 bits (445), Expect = 1e-43, Method: Composition-based stats.
Identities = 90/577 (16%), Positives = 172/577 (30%), Gaps = 65/577 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN-FTLKSEWATHKFADCKAKRDTPTSCT 183
PP KP + + + W+ G + +T+++ + +
Sbjct 1407 PPSKP-LVRQEDVRARSVLLSWEPGSDGLSPVRFYTVQTRELPSGEWALHPASISHNATA 1465
Query 184 VDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVY-KVKPN-PPHNLSVINSEELSSIL 240
+ F + + V+A N +G + + P P LSV + ++ +
Sbjct 1466 FVVDRLKPFTSYKFRVKATNDIGDSEYSEESESLTTLQAAPEEAPTILSV--TPHTTTSV 1523
Query 241 KLTWTNPSIK--SVIILKYNIQYRT---------------KDASTWSQIPPEDTA----- 278
+ W PS + I+L + ++YR +TW+++ P
Sbjct 1524 LIRWQPPSEDKINGILLGFRLRYRELLYDSLRGFTLHGIGNPGATWAELTPVYAVHNLSE 1583
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+ + + + +L Y R+ G+G S E G E P+ AP
Sbjct 1584 VSLTQYELDNLSKHRRYEIRMSVYNAVGEGPPSPPQEVFVG---EAMPTGAPQNVAVKAA 1640
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY-------TVNATKLTVNL 391
+ TQ + + W+ P NG I Y++ + ++ KL
Sbjct 1641 TATQ----LDVTWEPPPTESQNGDIQGYKIHFWEAQRQNESARVKTLFLPETGVKLKNLT 1696
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK-AFPKDNMLWVEWTTPR--- 447
Y ++ N G + A ++ + + V W P
Sbjct 1697 GYTSYWVSIAAFNAAGDGPRSTPVTARTQQAAPSAPGSIRFSELTTTSVNVSWEPPPLPN 1756
Query 448 ESVKKYILEW--CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
++ Y L + C+ D I + + ++ LAE Y + G
Sbjct 1757 GILEGYRLVYEPCMPVDGVSKIVTVDVKGNSPLWMKVKD-LAEGITYRFRIRAKTFA-YG 1814
Query 506 SPESIKAYLKQAPPSKGPTVRT-KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN 564
+ GP + + W G I Y I R
Sbjct 1815 PDVEANITTGPGEGAPGPPGEPFISRYGSAITIHWTSGDPGQ--GPITRYVIEARPSDEG 1872
Query 565 ETAVNVDSSHTEYT-----LSSLTSDTLYMVRMAAYTDEGGK----DGPEFTFTT--PKF 613
+ + E T + L Y R+ A D G P + P +
Sbjct 1873 LWDILIKDIPKEVTSYTFSMDILKQGVSYDFRVIAVNDYGYGTPSTPSPSVSAQKANPFY 1932
Query 614 AQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKH 650
+ ++ V L F+L + ++ + KK
Sbjct 1933 EEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKS 1969
Score = 171 bits (434), Expect = 3e-42, Method: Composition-based stats.
Identities = 101/545 (19%), Positives = 166/545 (30%), Gaps = 54/545 (10%)
Query 125 PP-EKPKNLSCIVNEGKKMRCEWDGGRETHLET-------NFTLKSEWATHKFADCKAKR 176
PP P+N+ + + +W E+H + L ++F +
Sbjct 694 PPFAPPQNVIASGRTNQSIMIQWQPPPESHQNGVLKGYIIRYCLAGLPVGYQFKNITNAD 753
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
+ + N E+ V A N+ G V S + + V PP N+ +
Sbjct 754 VNNLLLE---DLIIWTNYEIEVAAYNSAGLGVYSMKVTEWTLQGVPTVPPGNVQTEATN- 809
Query 236 LSSILKLTWTNPSIK--SVIILKYN-IQYRTKDASTWSQIPPEDTASTRSSF-TVQDLKP 291
S+ ++ TW PS + + I Y I + + + + V LK
Sbjct 810 -STTIRFTWNPPSPQFINGINQGYKLIAWEPEHEEEATVVTVRPNFQDSVHVGYVVGLKK 868
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
FTEY+ + C G G S T+ED P + S ++++ W
Sbjct 869 FTEYLTSVLCFTTPGDG---PRSPPQLVRTHEDVPGP----VGHLSFSEILDT-SLKVSW 920
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT------NDRYLATLTVRNL 405
+ P E NG + Y ++ + T +T+ Y +
Sbjct 921 QE--PLEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTS 978
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT-TPRESVKKYILEWCVLSD-- 462
G+ + TI + V P K I W V +
Sbjct 979 KGQGQVSSSTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWQVEAQVG 1038
Query 463 KAPCITDW----QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK--Q 516
+ +W Q + R+ NL Y + V G P ++ Q
Sbjct 1039 QNGEAEEWGLVHQLANEPDARSLEVPNLNPYTYYSFRMRQVNIVGTSPPSLPSRRIQTLQ 1098
Query 517 APPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNG--FIRNYTIFY-RTIIGNETAVNV-- 570
APP P V + + L W L NG Y I Y R+ V+V
Sbjct 1099 APPDVAPANVTLRTASETSLWLRWMPLLEQEYNGNPDSVGYRIRYLRSDGQGRAVVHVIH 1158
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF-----TTPKFAQGEIEAIVVPV 625
D EYT+ L T Y V++ A+ G + P + A
Sbjct 1159 DRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSHLVLGRTRESVPSSGPSNVSAQATSS 1218
Query 626 CLAFL 630
+
Sbjct 1219 SNMLV 1223
Score = 69.1 bits (167), Expect = 2e-10, Method: Composition-based stats.
Identities = 35/282 (12%), Positives = 67/282 (24%), Gaps = 21/282 (7%)
Query 52 EKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTC----NILT 107
+ I + + + + V ++ N
Sbjct 1653 PTESQNGDIQGYKIHFWEAQRQNESARVKTLFLPETGVKLKNLTGYTSYWVSIAAFNAAG 1712
Query 108 FGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATH 167
G V T + P P ++ + W+ L
Sbjct 1713 DGPRSTPVTARTQQA--APSAPGSIRFSELTTTSVNVSWEPPP---LPNGILEGYRLVYE 1767
Query 168 KFADCKAKRDTPTSCTVDYSTVYF--------VNIEVWVEAENALGKVTSDHINFDPVYK 219
T S ++ + + A+ + +
Sbjct 1768 PCMPVDGVSKIVTVDVKGNSPLWMKVKDLAEGITYRFRIRAKTF---AYGPDVEANITTG 1824
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
P S + + WT+ I +Y I+ R D W + +
Sbjct 1825 PGEGAPGPPGEPFISRYGSAITIHWTSGDPGQGPITRYVIEARPSDEGLWDILIKDIPKE 1884
Query 280 -TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
T +F++ LK Y FR+ + + G G S S S
Sbjct 1885 VTSYTFSMDILKQGVSYDFRVIAVNDYGYGTPSTPSPSVSAQ 1926
>sp|Q7Z5N4|SDK1_HUMAN Protein sidekick-1 OS=Homo sapiens OX=9606
GN=SDK1 PE=2 SV=3
Length=2213
Score = 290 bits (743), Expect = 8e-81, Method: Composition-based stats.
Identities = 129/581 (22%), Positives = 219/581 (38%), Gaps = 63/581 (11%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRET---HLETNF-T 159
N + G + V G T S +P P+N+S ++ W E L +
Sbjct 1256 NAVGAGPWSEVVRGRTRES-VPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKI 1314
Query 160 LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK-VTSDHINFDPVY 218
L R T + FV E+ V A +G V S + +
Sbjct 1315 LFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTK 1374
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
P PP + ++ E + +++ W P + IIL Y I YR +S + E
Sbjct 1375 DDAPGPP--VRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVE-VG 1431
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+T FT DL P + Y+FR+ G W + E A+ IT E R AP + P
Sbjct 1432 ATVRQFTATDLAPESAYIFRLSAKTRQG---WGEPLE-ATVITTEKRERPAPPRELLV-P 1486
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDY-----EVTLTRWKSHLQNYTVNATKLTVNLTN 393
R+++L W +P + I + E+ W+++ + + AT V+
Sbjct 1487 QAEVTARSLRLQW--VPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLR 1544
Query 394 --DRYLATLTVRNLVGKSDAAVLTIPACDFQ--ATHPVMDLKAFPKD-NMLWVEWTTPRE 448
Y L N +G SD + T Q P + A P + + ++W PR+
Sbjct 1545 PFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRD 1604
Query 449 S-----VKKYILEWCVLSDKAPCITDWQQ--------------------EDGTVHRTYLR 483
++ Y + + L +A T+ + +
Sbjct 1605 ESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCEL 1664
Query 484 GNLAESKCYLITVTPVYADGPGSPE-SIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQ 541
+L + + Y + +T G ++ ++ +A P+ P V+ + ++ + WD
Sbjct 1665 THLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDP 1724
Query 542 LPVDVQNGFIRNYTIFYRTII-GNETAVN--VDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
P + QNG I+ Y I+Y NET + L +LTS T Y+V ++A+
Sbjct 1725 PPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAA 1784
Query 599 GGKDGPEFTFTTPKFAQGEIEAIVVPVCLAF--LLTTLLGV 637
G DGP+ + P+ + A P LAF + +T L V
Sbjct 1785 G--DGPK---SDPQQGRTHQAAPGAPSFLAFSEITSTTLNV 1820
Score = 203 bits (517), Expect = 2e-52, Method: Composition-based stats.
Identities = 107/597 (18%), Positives = 207/597 (35%), Gaps = 58/597 (10%)
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW 269
D P+ P NL V + S + L+W P + IL Y ++ ++
Sbjct 656 DSRMARLEVIELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSPW- 714
Query 270 SQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
++ + + TV L P Y FR+ + E G+G +S +E + + E+ PS
Sbjct 715 -KVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYS--AETSRLMLPEEPPSAP 771
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV 389
P + + +++ + W+ P E NG + Y + + N T V
Sbjct 772 PKN----IVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEV 827
Query 390 N-------LTNDRYLATLTVRNLVGKSDAAV-LTIPACDFQATHPVMDLKAFP-KDNMLW 440
N + +Y + N G + +T T P +++ +
Sbjct 828 NYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQ 887
Query 441 VEWTTPRESVKKYI-LEWCVLSD--KAPCITDWQQEDGTVHRTY--LRGNLAESKCYLIT 495
W P + I + +L+ AP H + NL + Y +
Sbjct 888 FLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTS 947
Query 496 VTPVYADGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
V G G P + ++ P + ++ + W + +NG I Y
Sbjct 948 VLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQE--PLEKNGIITGY 1005
Query 555 TIFYRTIIGNETAV--NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
I + N++ + ++S+ EY + L+S T Y + +AA T G T ++
Sbjct 1006 QISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISS-- 1063
Query 613 FAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWS--PHT 670
VP L + L+ L + + K+ I++W
Sbjct 1064 ---------GVPPDLPGAPSNLVISNISPRSATLQFRPGYD-----GKTSISRWIVEGQV 1109
Query 671 PPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGG 730
+ +Y + N D ++EI + F+ +++N G S
Sbjct 1110 GAIGDEEEWVTLYEEENEPDAQMLEIPNLTP-------YTHYRFRMKQVNIVGPSPYSPS 1162
Query 731 SSCMSS--SRPSIS-SSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQV---FSRSE 781
S + + + P ++ +S ++ TS +++ + S Y SV + RS+
Sbjct 1163 SRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSD 1219
Score = 186 bits (473), Expect = 6e-47, Method: Composition-based stats.
Identities = 98/573 (17%), Positives = 178/573 (31%), Gaps = 66/573 (12%)
Query 126 PEKPKNLSCIVNEGK--KMRCEWDGGRETHLETNF-TLKSEWATHKFADCKAKRDTPTSC 182
P P+ L E +R +W G + + T++ + + +
Sbjct 1477 PAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEAT 1536
Query 183 TVDYSTVY-FVNIEVWVEAENALGKV--TSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ F + ++ ++A N +G +S+ + V PP SV + +S
Sbjct 1537 ACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPG--SVSATPHTTSS 1594
Query 240 LKLTWTNPSIK--SVIILKYNIQYRT---------------------KDASTWSQIPPED 276
+ + W P + + ++ Y I YR + + S +
Sbjct 1595 VLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVN 1654
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
++ST + + LK + Y + G+ S S E P+ AP
Sbjct 1655 SSSTSTMCELTHLKKYRRYEVIMTAYNIIGE---SPASAPVEVFVGEAAPAMAPQNVQVT 1711
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN-------YTVNATKLTV 389
+ +Q +++ W PP NG I Y++ S + +L
Sbjct 1712 PLTASQ----LEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKN 1767
Query 390 NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK-AFPKDNMLWVEWTTP-- 446
++ +YL +++ N G + A L + L V W P
Sbjct 1768 LTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAA 1827
Query 447 -RESVKKYILEWCVLSDKAPCITDWQ-QEDGTVHRTYLRGNLAESKCYLITVTPVY-ADG 503
++ Y + + L+ + G R +L + Y V G
Sbjct 1828 ANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYG 1887
Query 504 PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
P +I A + P V K +E L+W + + Y I R
Sbjct 1888 PELQANITAGPAEGSPGSPRDVLVTK-SASELTLQWTEGH--SGDTPTTGYVIEARPSDE 1944
Query 564 ---NETAVNVDSSHTEYTLS--SLTSDTLYMVRMAAYTDEGGKD--GPEFTFTTPKFAQG 616
+ ++ S T YTLS L Y R+ A + G + P + A
Sbjct 1945 GLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAPF 2004
Query 617 EIEAI-----VVPVCLAFLLTTLLGVLFCFNKR 644
E + + LL VL NK+
Sbjct 2005 YEEWWFLLVMALSSLIVILLVVFALVLHGQNKK 2037
Score = 185 bits (469), Expect = 2e-46, Method: Composition-based stats.
Identities = 102/559 (18%), Positives = 185/559 (33%), Gaps = 53/559 (9%)
Query 92 TDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPK-------------NLSCIVNE 138
D ++ N+ F +V T PP P+ +LS
Sbjct 925 PDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEIL 984
Query 139 GKKMRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
++ W + + + T + + E + ++ T +
Sbjct 985 DTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTID 1044
Query 198 VEAENALGK--VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
V A A+G VTS I+ + P P NL + N L + I
Sbjct 1045 VAAVTAVGTGLVTSSTISSGVPPDL-PGAPSNLVISNI--SPRSATLQFRPGYDGKTSIS 1101
Query 256 KYNIQYRTK---DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
++ ++ + D W + E+ + +L P+T Y FR++ + G +S
Sbjct 1102 RWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSP 1161
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR 372
S T + P AP+ T +++L W LP + NG +
Sbjct 1162 SS--RVIQTLQAPPDVAPTSVTV----RTASETSLRLRWVPLPDSQYNGNPESVGYRIKY 1215
Query 373 WKSHLQNYTVNATKLTVNLTNDRYLAT-----------LTVRNLVGKSDAA-VLTIPACD 420
W+S LQ+ V ++ + + + N VG + V+ +
Sbjct 1216 WRSDLQSSAV--AQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRE 1273
Query 421 FQATHPVMDLKAFP-KDNMLWVEWTTPRE-SVKKYILEWCVLSD--KAPCITDWQQEDGT 476
+ ++ A + + WT+ E IL + +L G
Sbjct 1274 SVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGN 1333
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPES--IKAYLKQAPPSKGPTVRTKKVGKNE 534
++ L L + Y + V G G P + I K P + +V
Sbjct 1334 HTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTS 1393
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYTLSSLTSDTLYMVR 591
+ W P + NG I Y I YR + T V V ++ ++T + L ++ Y+ R
Sbjct 1394 VRIVWQ--PPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFR 1451
Query 592 MAAYTDEGGKDGPEFTFTT 610
++A T +G + E T T
Sbjct 1452 LSAKTRQGWGEPLEATVIT 1470
Score = 172 bits (435), Expect = 3e-42, Method: Composition-based stats.
Identities = 109/658 (17%), Positives = 195/658 (30%), Gaps = 71/658 (11%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
PE VV + T C V+ Y+ K N P I+ S+ +
Sbjct 580 PEDHVVIKGTTATLHC----GATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLIS 635
Query 93 DIASLNIQ-LTCNILTFGQLEQNVYGITIISGLPPEKPKNL--SCIVNEGKKMRCEWDGG 149
S +I +C I++ G + + + P P+NL S + + W
Sbjct 636 QTWSGDIGDYSCEIVSEGGNDSRM--ARLEVIELPHSPQNLLVSPNSSHSHAVVLSWVRP 693
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSC-TVDYSTVYFVNIEVWVEAENALGKVT 208
+ + + + + P + V A N +G+
Sbjct 694 FDGNSPILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQ 753
Query 209 SDHINFDPVYKVKP--NPPHNLSVINSEELSSILKLTWTNPSIK--SVIILKYNIQYRTK 264
+ +P PP N+ + S + + + W P + ++ Y ++YR
Sbjct 754 YSAETSRLMLPEEPPSAPPKNI--VASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLA 811
Query 265 DASTWSQIPPEDTASTRSSF-TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+ + S ++ V DL +T+Y ++ G G +S E T +
Sbjct 812 GLPG--EYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEY---TLQ 866
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN---- 379
P+ P + T+Q +W P NG Y++ +
Sbjct 867 GVPTAPPQNV----QTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVT 922
Query 380 -----YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK-AF 433
+ V+ +T Y ++ G + + V L
Sbjct 923 IAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTE 982
Query 434 PKDNMLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
D L V W P E + Y + W V +T + T H ++G L+
Sbjct 983 ILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLT--HTLNSTTHEYKIQG-LSSLT 1039
Query 491 CYLITVTPVYADGPGS--PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ---LPVD 545
Y I V V A G G +I + + P + + A L++
Sbjct 1040 TYTIDVAAVTAVGTGLVTSSTISSGVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTS 1099
Query 546 VQNGFIRNYTIFYRTIIGNETAVNVDSSHTE-----YTLSSLTSDTLYMVRMAAYTDEGG 600
+ + I E V + E + +LT T Y RM G
Sbjct 1100 ISRWIVEGQV---GAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGP 1156
Query 601 KD-GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPD 657
P I+ + P +A T+ + + W +PD
Sbjct 1157 SPYSPSSRV---------IQTLQAPPDVAPTSVTVRT------ASETSLRLRWVPLPD 1199
Score = 126 bits (317), Expect = 4e-28, Method: Composition-based stats.
Identities = 78/449 (17%), Positives = 134/449 (30%), Gaps = 59/449 (13%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-------- 155
N + +T + +P E P ++S + + +W R+ L
Sbjct 1557 NDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRI 1616
Query 156 -------------------TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV 196
L +E T T C + + Y EV
Sbjct 1617 YYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYR-RYEV 1675
Query 197 WVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK--SVI 253
+ A N +G+ S + P N+ V + +S L++TW P + +
Sbjct 1676 IMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQV--TPLTASQLEVTWDPPPPESQNGN 1733
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
I Y I Y D+ ++ + +++L T+Y+ I G G SD
Sbjct 1734 IQGYKIYYWEADSQNETE-KMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSD- 1791
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
G T++ P APSF + + T T+ + W P ANG + Y V
Sbjct 1792 --PQQGRTHQAAP-GAPSFLAFSEITST----TLNVSWGE--PAAANGILQGYRVVYEPL 1842
Query 374 KSHLQNYTVNATKLTVNLTND----------RYLATLTVRNLVGKSDAAVLTIPACDFQA 423
V ++ N Y + R + + +
Sbjct 1843 APVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEGS 1902
Query 424 THPVMDLKAFPKDNMLWVEWTTPRE---SVKKYILEWCVLSDKAPCITDWQQEDGTVHR- 479
D+ + L ++WT Y++E SD+ + +
Sbjct 1903 PGSPRDVLVTKSASELTLQWTEGHSGDTPTTGYVIE-ARPSDEGLWDMFVKDIPRSATSY 1961
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPE 508
T L + Y V V G G P
Sbjct 1962 TLSLDKLRQGVTYEFRVVAVNEAGYGEPS 1990
>sp|Q8IWV2|CNTN4_HUMAN Contactin-4 OS=Homo sapiens OX=9606 GN=CNTN4
PE=1 SV=1
Length=1026
Score = 285 bits (729), Expect = 1e-80, Method: Composition-based stats.
Identities = 114/638 (18%), Positives = 208/638 (33%), Gaps = 62/638 (10%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
+V++ C + + I KE I ++ ++
Sbjct 418 LVKVGGEVVIEC--------KPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTK 469
Query 97 LNI-QLTCNILTF----GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRE 151
+ TC V +PP S V G+ + +
Sbjct 470 SDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPS-----SMDVTVGESIVLPCQVTHD 524
Query 152 THLETNFT-------LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
L+ FT + + F + + + V+
Sbjct 525 HSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQ----- 579
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK 264
V D + + P PP +++ E + +L+W I Y IQ RT
Sbjct 580 TSVDRLSAAADLIVRGPPGPPEAVTID--EITDTTAQLSWRPGPDNHSPITMYVIQARTP 637
Query 265 DASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ W + PE + TV L P+ EY FR G G S SE+ T
Sbjct 638 FSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRR--TE 695
Query 323 EDRPSKAPSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
E P P+ + S G ++ + + W+T+P NG+ Y V + + T
Sbjct 696 EALPEVTPA-----NVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLT 750
Query 382 VNATKLTVNL--------TNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLKA 432
V A+ + + V N G+ + + + + + T P + A
Sbjct 751 VLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFA 810
Query 433 FPKD-NMLWVEWTTP----RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
+ V W +P R ++ Y +++ DK + G T + NL
Sbjct 811 RSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTV-GNQTSTKI-TNLK 868
Query 488 ESKCYLITVTPVYADGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDV 546
S Y + V + G G ++ ++ PPS+ P ++ +L WDQ+
Sbjct 869 GSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALD 928
Query 547 QNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
++ Y + YR + T+V ++++ T L SL D Y++ + ++D GG
Sbjct 929 NESEVKGYKVLYRWNRQSSTSV-IETNKTSVEL-SLPFDEDYIIEIKPFSD-GGDGSSSE 985
Query 607 TFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
PK + A L+ + ++ R
Sbjct 986 QIRIPKISNAYARGSGASTSNACTLSAISTIMISLTAR 1023
Score = 133 bits (333), Expect = 2e-30, Method: Composition-based stats.
Identities = 82/512 (16%), Positives = 161/512 (31%), Gaps = 59/512 (12%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIV--WKTNHFTIPKEQYTIINRTASS 88
+ P S V + + C H ++ IV W N I +
Sbjct 502 VPPSSMDVTVGESIVLPC-------QVTHDHSLDIVFTWSFNGHLI---DFDRDGDHFER 551
Query 89 VTFTD------IASLNIQLTCNILTFGQLEQNVY--GITIISGLPPEKPKNLSCIVNEGK 140
V D I ++ ++ + Q + +I PP P+ ++
Sbjct 552 VGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDT 611
Query 141 KMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAK----RDTPTSCTVDYSTVYFVNIE 195
+ W G + H T + +++ + D T +V E
Sbjct 612 TAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYE 671
Query 196 VWVEAENALGKV-TSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWT--NPSIKS 251
A N +G S + P P N V S L +TW +++
Sbjct 672 FRTVAANVIGIGEPSRPSEKRRTEEALPEVTPAN--VSGGGGSKSELVITWETVPEELQN 729
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
Y + +R W ++R F + + PF+ + ++ G+G +
Sbjct 730 GRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPF- 788
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
S + E+ P+K P+ + + +++ W P + G+I YEV
Sbjct 789 --SPTTVVYSAEEEPTKPPAS----IFARSLSATDIEVFW-ASPLEKNRGRIQGYEVKYW 841
Query 372 RWKSHLQNY-----TVNATKLTVNLTNDR--YLATLTVRNLVGKSD-AAVLTIPACDFQA 423
R + +N N T + Y + N G +A + +
Sbjct 842 RHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPP 901
Query 424 THPVMDLKAFPKDNMLWVEWTTPR-ESVKKYILEWCVLSDKAPCITDWQQEDGT----VH 478
+ P ++ D+ + + W + + + + VL W ++ T +
Sbjct 902 SQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYR-------WNRQSSTSVIETN 954
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
+T + +L + Y+I + P G GS
Sbjct 955 KTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQ 986
>sp|Q62845|CNTN4_RAT Contactin-4 OS=Rattus norvegicus OX=10116
GN=Cntn4 PE=1 SV=1
Length=1026
Score = 285 bits (728), Expect = 1e-80, Method: Composition-based stats.
Identities = 111/638 (17%), Positives = 216/638 (34%), Gaps = 62/638 (10%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
+V++ C + + I +E I ++ ++
Sbjct 418 LVKVGGEVVIEC--------KPKASPRPVYTWRKGREILRENERITISEDGNLRIINVTK 469
Query 97 LNI-QLTCNILTFGQLEQNVYGITII----SGLPPEKPKNLSCIVNEGKKMRCEWDGGRE 151
+ TC + + + +PP S V G+ + +
Sbjct 470 SDAGSYTCIATNHFGTASSTGNVVVKDPTKVMVPPS-----SMDVTVGESIVLPCQVTHD 524
Query 152 THLETNFT-------LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
L+ FT + + F + + + V+ ++
Sbjct 525 HSLDIVFTWTFNGHLIDFDKDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQ--TSV 582
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK 264
K+++ D + + P PP +++ E + +L+W I Y IQ RT
Sbjct 583 DKLSA---AADLIVRGPPGPPEAVTID--EITDTTAQLSWRPGPDNHSPITMYVIQARTP 637
Query 265 DASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ W + PE + TV L P+ EY FR G G S SE+ T
Sbjct 638 FSVGWQAVSTVPELVDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRR--TE 695
Query 323 EDRPSKAPSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
E P P+ + S G ++ + + W+T+P NG+ Y V + T
Sbjct 696 EALPEVTPA-----NVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPHGKMIWMLT 750
Query 382 VNAT--------KLTVNLTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLKA 432
V A+ + + + V N G+ + + + + + T P + A
Sbjct 751 VLASADASRYVFRNESVRPFSPFEVKVGVFNNKGEGPFSPTTLVYSAEEEPTKPPASIFA 810
Query 433 FPKD-NMLWVEWTTP----RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
+ V W +P R ++ Y +++ DK + G T + NL
Sbjct 811 RSLSATDIEVFWASPIGKNRGRIQGYEVKYWRHDDKEENARKIRTV-GNQTSTKI-TNLK 868
Query 488 ESKCYLITVTPVYADGPGSPES-IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDV 546
+ Y ++V + G G + + ++ PPS+ P ++ +L WDQ+
Sbjct 869 GNALYHLSVKAYNSAGTGPSSAAVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALD 928
Query 547 QNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
++ Y + YR + T+V ++++ T L SL D Y++ + ++D GG
Sbjct 929 NESEVKGYKVLYRWNRQSSTSV-IETNKTSVEL-SLPFDEDYIIEIKPFSD-GGDGSSSE 985
Query 607 TFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
PK + A L+ + ++ R
Sbjct 986 QIRIPKISNSYARGSGASTSNACTLSAISTIMISLTAR 1023
Score = 132 bits (332), Expect = 4e-30, Method: Composition-based stats.
Identities = 86/523 (16%), Positives = 169/523 (32%), Gaps = 60/523 (11%)
Query 21 TGELLDPCGYISPESPV-VQLHSNFTAVCVLKEKCMDYFHVNANYIV--WKTNHFTIPKE 77
+ DP + P S + V + + C H ++ IV W N I
Sbjct 491 NVVVKDPTKVMVPPSSMDVTVGESIVLPC-------QVTHDHSLDIVFTWTFNGHLI--- 540
Query 78 QYTIINRTASSVTFTD------IASLNIQLTCNILTFGQLEQNVY--GITIISGLPPEKP 129
+ V D I ++ ++ + Q + +I PP P
Sbjct 541 DFDKDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDKLSAAADLIVRGPPGPP 600
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKR----DTPTSCTV 184
+ ++ + W G + H T + +++ + D T
Sbjct 601 EAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELVDGKTFTAT 660
Query 185 DYSTVYFVNIEVWVEAENALGKV-TSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKL 242
+V E A N +G S + P P N V S L +
Sbjct 661 VVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPAN--VSGGGGSKSELVI 718
Query 243 TWT--NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
TW +++ Y + +R W ++R F + ++PF+ + ++
Sbjct 719 TWETVPEELQNGRGFGYVVAFRPHGKMIWMLTVLASADASRYVFRNESVRPFSPFEVKVG 778
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
G+G + S + E+ P+K P+ + + +++ W P +
Sbjct 779 VFNNKGEGPF---SPTTLVYSAEEEPTKPPAS----IFARSLSATDIEVFW-ASPIGKNR 830
Query 361 GKILDYEVTLTRWKSHLQNY-------TVNATKLTVNLTNDRYLATLTVRNLVGKSD-AA 412
G+I YEV R +N +TK+T N Y ++ N G +A
Sbjct 831 GRIQGYEVKYWRHDDKEENARKIRTVGNQTSTKITNLKGNALYHLSVKAYNSAGTGPSSA 890
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR-ESVKKYILEWCVLSDKAPCITDWQ 471
+ + + P ++ D+ + + W + + + + VL W
Sbjct 891 AVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYR-------WN 943
Query 472 QEDGT----VHRTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
++ T ++T + +L + Y+I + P G GS
Sbjct 944 RQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQ 986
>sp|Q62682|CNTN3_RAT Contactin-3 OS=Rattus norvegicus OX=10116
GN=Cntn3 PE=1 SV=1
Length=1028
Score = 285 bits (728), Expect = 2e-80, Method: Composition-based stats.
Identities = 126/641 (20%), Positives = 213/641 (33%), Gaps = 76/641 (12%)
Query 38 VQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASL 97
VQ+ S C + + + T+ +EQ I + ++
Sbjct 421 VQVGSLVILDC--------KPSASPRALSFWKKGDTVVREQARISLLNDGGLKIMNVTKA 472
Query 98 NI-QLTCNILT-FGQLEQNVYGITIISGLPPE----KPKNLSCIVNEGKKMRCE------ 145
+ TC FG+ G T + P P N+ V E + C+
Sbjct 473 DAGIYTCIAENQFGKAN----GTTQLVVTEPTRIILAPSNMDVAVGESIILPCQVQHDPL 528
Query 146 ------WDGGRETHLETNFTLK-SEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
W N TL + F + + +
Sbjct 529 LDIMFAW--------YFNGTLTDFKKDGSHFEKVGGSSSGDLMIR---NIQLKHSGKYVC 577
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
+ + V+S + + + P PP N+ V E + +L+WT + ++ Y
Sbjct 578 MVQTGVDSVSS---AAELIVRGSPGPPENVKVD--EITDTTAQLSWTEGTDSHSPVISYA 632
Query 259 IQYRTKDASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
+Q RT + W + PE + TV +L P+ EY FR+ + G G S SE+
Sbjct 633 VQARTPFSVGWQNVRTVPEAIDGKTRTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEK 692
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTR--- 372
T E P APS + S G R+ + + W +P NG Y V
Sbjct 693 VR--TEEAAPEVAPS-----EVSGGGGSRSELVITWDPVPEELQNGGGFGYVVAFRPLGV 745
Query 373 --WKSHLQNYTVNATKLTVN---LTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHP 426
W + N + N + Y + V N G+ + V T+ + + + T
Sbjct 746 TTWIQTVVTSPDNPRYVFRNESIVPFSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVA 805
Query 427 VMDLKAFP-KDNMLWVEWTT-PRESVKKYILEWCVLSD---KAPCITDWQQEDGTVHRTY 481
+ A + + V W T P +S +L + V + + G
Sbjct 806 PSHISAHSLSSSEIEVSWNTIPWKSSNGRLLGYEVRYWNNGGEEESSSKVKVAGNQTSAV 865
Query 482 LRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
LRG L + Y V G G ++ A K+ PPS+ P + +L W+
Sbjct 866 LRG-LKSNLAYYTAVRAYNTAGAGPFSATVNATTKKTPPSQPPGNVVWNATDTKVLLNWE 924
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
Q+ + Y +FYRT N V + + L + D Y++ + A TD GG
Sbjct 925 QVKALENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELLLPIKED--YIIEVKATTD-GG 981
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCF 641
P+ + + ++ + VL F
Sbjct 982 DGTSSEQIRIPRITSMDARGSTSAISDIHPVSGYISVLLFF 1022
Score = 140 bits (353), Expect = 1e-32, Method: Composition-based stats.
Identities = 81/506 (16%), Positives = 159/506 (31%), Gaps = 47/506 (9%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFT--IPKEQYTIINRTASS 88
++P + V + + C ++ + W N K+ SS
Sbjct 504 LAPSNMDVAVGESIILPCQVQHDPLLDIMFA-----WYFNGTLTDFKKDGSHFEKVGGSS 558
Query 89 VTFTDIASLNIQLTCNILTFGQLEQNVY--GITIISGLPPEKPKNLSCIVNEGKKMRCEW 146
I ++ ++ + + Q + +I P P+N+ + W
Sbjct 559 SGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAAELIVRGSPGPPENVKVDEITDTTAQLSW 618
Query 147 DGGRETHLET-NFTLKSEWAT----HKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAE 201
G ++H ++ +++ D T +V E V A
Sbjct 619 TEGTDSHSPVISYAVQARTPFSVGWQNVRTVPEAIDGKTRTATVVELNPWVEYEFRVVAS 678
Query 202 NALGKV-TSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWT--NPSIKSVIILKY 257
N +G S + P P V S L +TW +++ Y
Sbjct 679 NKIGGGEPSLPSEKVRTEEAAPEVAPS--EVSGGGGSRSELVITWDPVPEELQNGGGFGY 736
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
+ +R +TW Q + R F + + PF+ Y ++ G+G + S
Sbjct 737 VVAFRPLGVTTWIQTVVTSPDNPRYVFRNESIVPFSPYEVKVGVYNNKGEGPF---SPVT 793
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL 377
+ + E+ P+ APS +H+ +++ W T+P +NG++L YEV
Sbjct 794 TVFSAEEEPTVAPSH----ISAHSLSSSEIEVSWNTIPWKSSNGRLLGYEVRYWNNGGEE 849
Query 378 QNYT-----VNATKLTVNLTND--RYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMD 429
++ + N T + Y + N G +A + + P +
Sbjct 850 ESSSKVKVAGNQTSAVLRGLKSNLAYYTAVRAYNTAGAGPFSATVNATTKKTPPSQPPGN 909
Query 430 LKAFPKDNMLWVEWTTPR-----ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
+ D + + W + V Y + + S + Q + L
Sbjct 910 VVWNATDTKVLLNWEQVKALENESEVTGYKVFYRTSSQN-----NVQVLNTNKTSAELLL 964
Query 485 NLAESKCYLITVTPVYADGPGSPESI 510
+ E Y+I V G G+
Sbjct 965 PIKED--YIIEVKATTDGGDGTSSEQ 988
>sp|Q69Z26|CNTN4_MOUSE Contactin-4 OS=Mus musculus OX=10090 GN=Cntn4
PE=1 SV=2
Length=1026
Score = 284 bits (727), Expect = 2e-80, Method: Composition-based stats.
Identities = 111/638 (17%), Positives = 212/638 (33%), Gaps = 62/638 (10%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
+V++ C + + I +E I ++ ++
Sbjct 418 LVKVGGEVVIEC--------KPKASPRPVYTWRKGREILRENERITISEDGNLRIINVTK 469
Query 97 LNI-QLTCNILTFGQLEQNVYGITII----SGLPPEKPKNLSCIVNEGKKMRCEWDGGRE 151
+ TC + + + +PP S V G+ + +
Sbjct 470 SDAGSYTCIATNHFGTASSTGNVIVKDPTKVMVPPS-----SMDVTVGESIVLPCQVTHD 524
Query 152 THLETNFT-------LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
L+ FT + + F + + + V+
Sbjct 525 HSLDIVFTWTFNGHLIDFDKDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQ----- 579
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK 264
V + D + + P PP +++ E + +L+W I Y IQ RT
Sbjct 580 TSVDKLSVAADLIVRGPPGPPEAVTID--EITDTTAQLSWRPGPDNHSPITMYVIQARTP 637
Query 265 DASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ W + P+ + TV L P+ EY FR G G S SE+ T
Sbjct 638 FSVGWQAVNTVPDLVDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRR--TE 695
Query 323 EDRPSKAPSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
E P P+ + S G ++ + + W+T+P NG+ Y V + T
Sbjct 696 EALPEVTPA-----NVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPHGKMIWMLT 750
Query 382 VNAT--------KLTVNLTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLKA 432
V A+ + + + V N G+ + + + + + T P + A
Sbjct 751 VLASADASRYVFRNESVRPFSPFEVKVGVFNNKGEGPFSPTTLVYSAEEEPTKPPASIFA 810
Query 433 FPKD-NMLWVEWTTP----RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
+ V W +P R ++ Y +++ DK + G T + NL
Sbjct 811 RSLSATDIEVFWASPIGKNRGRIQGYEVKYWRHDDKEENAKKIRTV-GNQTSTKI-TNLK 868
Query 488 ESKCYLITVTPVYADGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDV 546
S Y ++V + G G ++ ++ PPS+ P ++ +L WDQ+
Sbjct 869 GSALYHLSVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALD 928
Query 547 QNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
++ Y + YR + T+V ++++ T L SL D Y++ + ++D GG
Sbjct 929 NESEVKGYKVLYRWNRQSSTSV-IETNKTSVEL-SLPFDEDYIIEIKPFSD-GGDGSSSE 985
Query 607 TFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
PK + A L+ + ++ R
Sbjct 986 QIRIPKISNSYARGSGASTSNACTLSAISTIMISLTAR 1023
>sp|Q9P232|CNTN3_HUMAN Contactin-3 OS=Homo sapiens OX=9606 GN=CNTN3
PE=1 SV=3
Length=1028
Score = 284 bits (727), Expect = 2e-80, Method: Composition-based stats.
Identities = 120/629 (19%), Positives = 221/629 (35%), Gaps = 52/629 (8%)
Query 38 VQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQ-YTIINRTASSVTFTDIAS 96
VQ+ S + C K + + WK ++ + + +++N + ++
Sbjct 421 VQVGSLVSLDC--KPRASPRALSS-----WKKGDVSVQEHERISLLNDGGLKI--ANVTK 471
Query 97 LNIQ-LTCNILT-FGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHL 154
+ TC FG+ + + P N+ V E + C+ + L
Sbjct 472 ADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQ--HDPLL 529
Query 155 ETNFTLKSEWATHKFA-DCKAKRDTPTSCTVDY---STVYFVNIEVWVEAENALGKVTSD 210
+ FT A F D S + D + + + + + V+S
Sbjct 530 DIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSS- 588
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS 270
D + + P PP N+ V E + +L+W ++ Y+IQ RT + W
Sbjct 589 --AADLIVRGSPGPPENVKVD--EITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQ 644
Query 271 QIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
+ PE + TV +L P+ EY FR+ + G G S SE+ T E P
Sbjct 645 TVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVR--TEEAVPEV 702
Query 329 APSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTR-----WKSHLQNYTV 382
PS + + G R+ + + W +P NG+ Y V W +
Sbjct 703 PPS-----EVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPD 757
Query 383 NATKLTVN---LTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLKAFP-KDN 437
+ N + Y + V N G+ + V T+ + + + T + A +
Sbjct 758 TPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSS 817
Query 438 MLWVEWTT-PRESVKKYILEWCVLSD---KAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
+ V W T P + ++L + V + + G LRG L + Y
Sbjct 818 EIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLRG-LKSNLAYY 876
Query 494 ITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
V + G G ++ K+ PPS+ P + +L W+Q+ +
Sbjct 877 TAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVT 936
Query 553 NYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
Y +FYRT N V ++++ T L L Y++ + A TD GG P+
Sbjct 937 GYKVFYRTSSQNNVQV-LNTNKTSAELV-LPIKEDYIIEVKATTD-GGDGTSSEQIRIPR 993
Query 613 FAQGEIEAIVVPVCLAFLLTTLLGVLFCF 641
+ + +++ + ++
Sbjct 994 ITSMDARGSTSAISNVHPMSSYMPIVLFL 1022
Score = 146 bits (367), Expect = 2e-34, Method: Composition-based stats.
Identities = 76/500 (15%), Positives = 162/500 (32%), Gaps = 35/500 (7%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFT--IPKEQYTIINRTASS 88
++P + V + + C ++ + W N K+ SS
Sbjct 504 LAPSNMDVSVGESVILPCQVQHDPLLDIIFT-----WYFNGALADFKKDGSHFEKVGGSS 558
Query 89 VTFTDIASLNIQLTCNILTFGQLEQNVY--GITIISGLPPEKPKNLSCIVNEGKKMRCEW 146
I ++ ++ + + Q + +I P P+N+ + W
Sbjct 559 SGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSW 618
Query 147 DGGRETHLET-NFTLKSEWAT----HKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAE 201
G++ H ++++++ D T +V E V A
Sbjct 619 KEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVAS 678
Query 202 NALGKV-TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN--PSIKSVIILKYN 258
N +G S + P P + V S L +TW +++ Y
Sbjct 679 NKIGGGEPSLPSEKVRTEEAVPEVPPS-EVNGGGGSRSELVITWDPVPEELQNGEGFGYV 737
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+ +R +TW Q + R F + + P++ Y ++ G+G + S +
Sbjct 738 VAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPF---SPVTT 794
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
+ E+ P+ APS +++ +++ W T+P +NG +L YEV +
Sbjct 795 VFSAEEEPTVAPSQVS----ANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEE 850
Query 379 NYT-------VNATKLTVNLTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDL 430
+ + + +L +N Y + N G +A + + + P ++
Sbjct 851 SSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNV 910
Query 431 KAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
D + + W + + + + + + Q + L + E
Sbjct 911 VWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKED- 969
Query 491 CYLITVTPVYADGPGSPESI 510
Y+I V G G+
Sbjct 970 -YIIEVKATTDGGDGTSSEQ 988
>sp|Q9UQ52|CNTN6_HUMAN Contactin-6 OS=Homo sapiens OX=9606 GN=CNTN6
PE=1 SV=1
Length=1028
Score = 277 bits (707), Expect = 1e-77, Method: Composition-based stats.
Identities = 90/460 (20%), Positives = 165/460 (36%), Gaps = 33/460 (7%)
Query 207 VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA 266
+ S D + + P PP ++ V + +S +L+W + I + IQ RT +
Sbjct 583 LESLSAVADIIVRGPPGPPEDVQVEDISSTTS--QLSWRAGPDNNSPIQIFTIQTRTPFS 640
Query 267 STWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
W + PE + TV L P+ EY FR+ G G S+ SE T
Sbjct 641 VGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLR--TKAS 698
Query 325 RPSKAPSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN---- 379
P AP ++ G R+ + + W+++P NG+ Y + S +
Sbjct 699 VPVVAP-----VNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKV 753
Query 380 YTVNATKLTVN----LTNDRYLATLTVRNLVGKSDAAVLTIP---ACDFQATHPVMDLKA 432
+V +++ + + + V N G+ + +TI + Q L++
Sbjct 754 SSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQS 813
Query 433 FPKDNMLW----VEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
F M + W V Y + + D + + G V + G L
Sbjct 814 FSASEMEVSWNAIAWNRNTGRVLGYEVLYWTD-DSKESMIGKIRVSGNVTTKNITG-LKA 871
Query 489 SKCYLITVTPVYADGPGSPES-IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
+ Y +V G G + K++PPS+ P K+ ++ L W+ +
Sbjct 872 NTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVKTMEN 931
Query 548 NGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
+ Y I YR ++T + ++ + L D Y++ + +GG
Sbjct 932 ESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFEED--YLIEIR-TVSDGGDGSSSEE 988
Query 608 FTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLI 647
PK + I L+ ++ + CF + LI
Sbjct 989 IRIPKMSSLSSRGIQFLEPSTHFLSIVIVIFHCFAIQPLI 1028
Score = 128 bits (321), Expect = 8e-29, Method: Composition-based stats.
Identities = 85/503 (17%), Positives = 162/503 (32%), Gaps = 43/503 (9%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTI-----PKEQYTIINRT 85
+ P V + + C + VW N I I +
Sbjct 504 VPPSKMDVTVGESIVLPCQVSHDPSI-----EVVFVWFFNGDVIDLKKGVAHFERIGGES 558
Query 86 ASSVTFTDIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRC 144
+ +I + + C + T + V II PP P+++ +
Sbjct 559 VGDLMIRNIQLHHSGKYLCTVQTTLESLSAV--ADIIVRGPPGPPEDVQVEDISSTTSQL 616
Query 145 EWDGGRETHLE-TNFTLKSEWATH-KFADCKAKRDTPTSCTVDYSTVY---FVNIEVWVE 199
W G + + FT+++ + + T + + V +V E V
Sbjct 617 SWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVV 676
Query 200 AENALGKV--TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT--NPSIKSVIIL 255
A N++G + V P N+ S L +TW +++
Sbjct 677 AGNSIGIGEPSEPSELLRTKASVPVVAPVNIH--GGGGSRSELVITWESIPEELQNGEGF 734
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y I +R ++TWS+ S+R + + + P + + ++ +G+G S +
Sbjct 735 GYIIMFRPVGSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTI 794
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
SG ED P AP + + +++ W + G++L YEV S
Sbjct 795 VYSG---EDEPQLAP----RGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDS 847
Query 376 HLQNYT---VNATKLTVNLT----NDRYLATLTVRNLVGKSDAAVLT-IPACDFQATHPV 427
V+ T N+T N Y A++ N G ++ + + P
Sbjct 848 KESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPP 907
Query 428 MDLKAFPKDNMLWVEWTTPRESVKK-YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
++ ++ L + W + + +L + +L + + L
Sbjct 908 ANIAWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKT-HILETNNTSAELLVPF 966
Query 487 AESKCYLITVTPVYADGPGSPES 509
E YLI + V G GS
Sbjct 967 EED--YLIEIRTVSDGGDGSSSE 987
>sp|A7MBJ4|PTPRF_BOVIN Receptor-type tyrosine-protein phosphatase
F OS=Bos taurus OX=9913 GN=PTPRF PE=2 SV=1
Length=1898
Score = 274 bits (699), Expect = 2e-75, Method: Composition-based stats.
Identities = 103/442 (23%), Positives = 163/442 (37%), Gaps = 45/442 (10%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A ++LG + + K P PP +L V +E ++ + LTW + S + Y I
Sbjct 300 AISSLGMIEATA---QVTVKALPKPPIDLVV--TETTATSVTLTWDSG--NSEPVSYYGI 352
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
QYR A Q E + +++ L PF+EY FR+ + G+G SE
Sbjct 353 QYRPAGAEGPFQ---EVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRG---PPSEAVRA 406
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR------- 372
T E PS P + + T+ + W+ PP E NG + Y V T
Sbjct 407 RTGEQAPSSPP----RRVQARMLSASTMLVQWE--PPEEPNGLVRGYRVYYTPDSRRPLS 460
Query 373 -WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDL 430
W H + + T + L Y + VG + + + P
Sbjct 461 AWHKHNTDAGLLTT-VGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQ 519
Query 431 KAFPKDNMLWVEWT-TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
D + + W P+E + KY L + D+ + +Y +L
Sbjct 520 AEVDSDTRIQLSWLLPPQERIVKYELVYWAAEDEGQQ----HKVTFDPTSSYTVEDLKPD 575
Query 490 KCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQ 547
Y + G G +I+A Q+ PS P V VG + W P D +
Sbjct 576 TLYRFQLAARSELGVGVFTPTIEARTAQSTPSAPPQKVTCVSVGSTTVRVSWVPPPADSR 635
Query 548 NGFIRNYTIFYRTIIGNETAVNVDS----SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
NG I Y++ Y + G + +V H+ + L L T Y V + A+TD G G
Sbjct 636 NGVITQYSVAYEAVDGEDRGRHVVDGIGREHSSWDLVGLEKWTEYRVWVRAHTDVG--PG 693
Query 604 PEFTFTTPKFAQGEIEAIVVPV 625
PE + P + + + P
Sbjct 694 PESS---PVLVRTDEDVPSGPP 712
Score = 236 bits (602), Expect = 6e-63, Method: Composition-based stats.
Identities = 109/556 (20%), Positives = 188/556 (34%), Gaps = 50/556 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P +P + V+ +++ W + + + L WA PTS
Sbjct 511 VPAQPADFQAEVDSDTRIQLSWLLPPQERI-VKYELVY-WAAEDEGQQHKVTFDPTSSYT 568
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ A + LG + P+ P V S+ ++++W
Sbjct 569 VEDLKPDTLYRFQLAARSELGVGVFTPTIEARTAQSTPSAP-PQKVTCVSVGSTTVRVSW 627
Query 245 TNP--SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
P ++ +I +Y++ Y D + + SS+ + L+ +TEY +R
Sbjct 628 VPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGIGREHSSWDLVGLEKWTEYRVWVRAH 687
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
+ G G S T ED PS P +++P V++ WK P + +G+
Sbjct 688 TDVGPGPESS---PVLVRTDEDVPSGPP-RKVEVEP---LNSTAVRVSWKLPVPSKQHGQ 740
Query 363 ILDYEVTLTRWKSHLQNYT----------VNATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
I Y+VT R ++ T ++ Y T+ G +
Sbjct 741 IRGYQVTYVRLENGEPRGAPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARS 800
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITD 469
I + + N ++W P + Y L++ + P D
Sbjct 801 KPKIVTTTGAVPGRPTMMVSTTAMNTALLQWHPPKELPGELLGYRLQYRRADEARPSTID 860
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK-GPTVRTK 528
+ ++D T L + Y+ +T G G + + PS +R
Sbjct 861 FGKDDQHFTVT----GLHKGATYIFRLTAKNRAGLGEEFEKEITTPEDVPSGFPQNLRVI 916
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLY 588
+ + L WD + +NG I NYT+ YR I + NV + T TLS L DT Y
Sbjct 917 GLTTSTTELIWDPPVLAERNGRITNYTVVYRDINSQQELQNVTA-DTHLTLSGLKPDTTY 975
Query 589 MVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLI 647
+++ A T +G P T ++ A V A + LL
Sbjct 976 DIKVRARTSKGAGPLSPSIQSRT--MPVEQVFAKNFRVEAAMKTSVLLSW---------- 1023
Query 648 KKHIWPNVPDPSKSHI 663
VPD KS +
Sbjct 1024 ------EVPDSYKSAV 1033
Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats.
Identities = 99/533 (19%), Positives = 171/533 (32%), Gaps = 42/533 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRET-HLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P P+ + + M +W+ E L + + + + K +T
Sbjct 413 PSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLL 472
Query 184 VDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
++ + + V A A+G + P P + + + ++L
Sbjct 473 TTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAE--VDSDTRIQL 530
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
+W P I+KY + Y + + T SS+TV+DLKP T Y F++
Sbjct 531 SWLLP--PQERIVKYELVYWAAEDEGQQH---KVTFDPTSSYTVEDLKPDTLYRFQLAAR 585
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
E G G + + T + PS P + G TV++ W P NG
Sbjct 586 SELGVGVF---TPTIEARTAQSTPSAPPQKVTCVSV----GSTTVRVSWVPPPADSRNGV 638
Query 363 ILDYEVTLTRWKSHLQNYTV-------NATKLTVNLTN-DRYLATLTVRNLVGKSDAAVL 414
I Y V + V +++ V L Y + VG +
Sbjct 639 ITQYSVAYEAVDGEDRGRHVVDGIGREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSP 698
Query 415 T-IPACDFQATHPVMDLKAFP-KDNMLWVEWTTP-----RESVKKYILEWCVLSDKAPCI 467
+ + + P ++ P + V W P ++ Y + + L + P
Sbjct 699 VLVRTDEDVPSGPPRKVEVEPLNSTAVRVSWKLPVPSKQHGQIRGYQVTYVRLENGEPRG 758
Query 468 TDWQQED--GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
Q+ T + G L Y ITV G G+ K PT+
Sbjct 759 APIIQDVMLAEAQETTISG-LTPETTYSITVAAYTTKGDGARSKPKIVTTTGAVPGRPTM 817
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDSSHTEYTLSSLTS 584
N A+L+W P G + Y + YR + ++ +T++ L
Sbjct 818 MVSTTAMNTALLQWH--PPKELPGELLGYRLQYRRADEARPSTIDFGKDDQHFTVTGLHK 875
Query 585 DTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGV 637
Y+ R+ A G + E TTP+ P L + T
Sbjct 876 GATYIFRLTAKNRAGLGEEFEKEITTPEDVPS-----GFPQNLRVIGLTTSTT 923
Score = 195 bits (494), Expect = 2e-49, Method: Composition-based stats.
Identities = 100/581 (17%), Positives = 169/581 (29%), Gaps = 56/581 (10%)
Query 63 NYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIIS 122
+ W +Q+ + SS T D+ + + +L V+ TI +
Sbjct 544 ELVYWAAED---EGQQHKVTFDPTSSYTVEDLK-PDTLYRFQLAARSELGVGVFTPTIEA 599
Query 123 ----GLPPEKPKNLSCIVNEGKKMRCEWDG-------GRETHLETNF-TLKSEWATHKFA 170
P P+ ++C+ +R W G T + + E
Sbjct 600 RTAQSTPSAPPQKVTCVSVGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVV 659
Query 171 DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLS 229
D + + + VWV A +G S + V PP +
Sbjct 660 DGIGREHSSWDLVG---LEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVE 716
Query 230 VINSEELSSILKLTWT--NPSIKSVIILKYNIQY-RTKDASTWSQIPPEDTASTRSS-FT 285
V S+ ++++W PS + I Y + Y R ++ +D + T
Sbjct 717 VEPLN--STAVRVSWKLPVPSKQHGQIRGYQVTYVRLENGEPRGAPIIQDVMLAEAQETT 774
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
+ L P T Y + G G S T P + T
Sbjct 775 ISGLTPETTYSITVAAYTTKGDGARSK---PKIVTTTGAVPGRPTMMV------STTAMN 825
Query 346 TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ---NYTVNATKLTVNLT--NDRYLATL 400
T L W PP E G++L Y + R ++ + TV Y+ L
Sbjct 826 TALLQWH--PPKELPGELLGYRLQYRRADEARPSTIDFGKDDQHFTVTGLHKGATYIFRL 883
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTP-RESVKKYILEWC 458
T +N G + I + + +L+ + + W P I +
Sbjct 884 TAKNRAGLGEEFEKEITTPEDVPSGFPQNLRVIGLTTSTTELIWDPPVLAERNGRITNYT 943
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQA 517
V+ + Q H T L Y I V + G G SI++
Sbjct 944 VVYRDINSQQELQNVTADTHLTL--SGLKPDTTYDIKVRARTSKGAGPLSPSIQSRTMPV 1001
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY 577
R + K +L W+ + I Y N +V VD
Sbjct 1002 EQVFAKNFRVEAAMKTSVLLSWEVPDSYKSAVP---FRILY-----NGQSVEVDGHSMRK 1053
Query 578 TLSSLTSDTLYMVRMAAY-TDEGGKDGPEFTFTTPKFAQGE 617
++ L +T Y + + GG T P +
Sbjct 1054 LIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPDLLPHK 1094
>sp|Q64604|PTPRF_RAT Receptor-type tyrosine-protein phosphatase
F OS=Rattus norvegicus OX=10116 GN=Ptprf PE=2 SV=1
Length=1898
Score = 272 bits (696), Expect = 6e-75, Method: Composition-based stats.
Identities = 114/607 (19%), Positives = 202/607 (33%), Gaps = 71/607 (12%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A ++LG + + K P PP +L V +E ++ + LTW + + + Y I
Sbjct 300 AISSLGMIEATA---QVTVKALPKPPIDLVV--TETTATSVTLTWDSG--NTEPVSFYGI 352
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
QYR Q E + +++ L PF+EY FR+ + G+G SE
Sbjct 353 QYRAAGTDGPFQ---EVDGVASTRYSIGGLSPFSEYAFRVLAVNSIGRG---PPSEAVRA 406
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR------- 372
T E PS P + + T+ + W+ PP E NG + Y V T
Sbjct 407 RTGEQAPSSPP----RRVQARMLSASTMLVQWE--PPEEPNGLVRGYRVYYTPDSRRPLS 460
Query 373 -WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDL 430
W H + + T + L Y + VG + + + P
Sbjct 461 AWHKHNTDAGLLTT-VGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQ 519
Query 431 KAFPKDNMLWVEWT-TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
D + + W P+E + KY L + D+ + +Y +L
Sbjct 520 AKAESDTRIQLSWLLPPQERIIKYELVYWAAEDEGQQ----HKVTFDPTSSYTLEDLKPD 575
Query 490 KCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQ 547
Y + G G +++A Q+ PS P V G + W P D +
Sbjct 576 TLYHFQLAARSDLGVGVFTPTVEACTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSR 635
Query 548 NGFIRNYTIFYRTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
NG I Y++ Y + G + +V H+ + L L T Y V + A+TD G G
Sbjct 636 NGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVG--PG 693
Query 604 PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHI 663
PE + P + + + P + + K VP+ I
Sbjct 694 PESS---PVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLP---------VPNKQHGQI 741
Query 664 AQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEG 723
+ N + Q + V + + S + T
Sbjct 742 RGYQVTYVRLENGEPRGQ-------PIIQDVMLAEAQETTI-----SGLTPETTYSITVA 789
Query 724 HSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSV-----QVFS 778
+ G + + + + + S+T ++ ++ ++P +
Sbjct 790 AYTTKGDGARSKPKVVTTTGAVPGRPTMMVSTTAMHTALLQWHPPKELPGELLGYRLQYR 849
Query 779 RSESTQP 785
R++ +P
Sbjct 850 RADEARP 856
Score = 235 bits (598), Expect = 2e-62, Method: Composition-based stats.
Identities = 105/557 (19%), Positives = 183/557 (33%), Gaps = 52/557 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P +P + +++ W +E ++ WA PTS
Sbjct 511 VPAQPADFQAKAESDTRIQLSWLLPPQERIIKYEL---VYWAAEDEGQQHKVTFDPTSSY 567
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
+ A + LG + P+ P V S+ ++++
Sbjct 568 TLEDLKPDTLYHFQLAARSDLGVGVFTPTVEACTAQSTPSAP-PQKVTCVSTGSTTVRVS 626
Query 244 WTNP--SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
W P ++ II +Y++ Y D + + + SS+ + L+ +TEY +R
Sbjct 627 WVPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRA 686
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ G G S T ED PS P +++P V + WK P + +G
Sbjct 687 HTDVGPGPESS---PVLVRTDEDVPSGPP-RKVEVEP---LNSTAVHVSWKLPVPNKQHG 739
Query 362 KILDYEVTLTRWKSHLQNYT----------VNATKLTVNLTNDRYLATLTVRNLVGKSDA 411
+I Y+VT R ++ T ++ Y T+ G
Sbjct 740 QIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGAR 799
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCIT 468
+ + + + + ++W P + Y L++ + P
Sbjct 800 SKPKVVTTTGAVPGRPTMMVSTTAMHTALLQWHPPKELPGELLGYRLQYRRADEARPNTI 859
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK-GPTVRT 527
D+ ++D T L + Y+ + GPG + + PS +R
Sbjct 860 DFGKDDQHFTVT----GLHKGATYIFRLAAKNRAGPGEEFEKEITTPEDAPSGFPQNLRV 915
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTL 587
+ + L WD + +NG I NYT+ YR I NV TL L DT
Sbjct 916 TGLTTSTTELAWDPPVLAERNGRITNYTVVYRDINSQHELQNVTG-DVHLTLLGLKPDTT 974
Query 588 YMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDL 646
Y +++ A+T +G P T ++ A V A + LL
Sbjct 975 YDIKVRAHTSKGAGPLSPSIQSRT--MPMEQVFAKNFRVAAAMKTSVLLSW--------- 1023
Query 647 IKKHIWPNVPDPSKSHI 663
VPD KS +
Sbjct 1024 -------EVPDSYKSAV 1033
Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats.
Identities = 97/533 (18%), Positives = 170/533 (32%), Gaps = 42/533 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRET-HLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P P+ + + M +W+ E L + + + + K +T
Sbjct 413 PSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLL 472
Query 184 VDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
++ + + V A A+G + P P + E + ++L
Sbjct 473 TTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAKA--ESDTRIQL 530
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
+W P I+KY + Y + + T SS+T++DLKP T Y F++
Sbjct 531 SWLLP--PQERIIKYELVYWAAEDEGQQH---KVTFDPTSSYTLEDLKPDTLYHFQLAAR 585
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
+ G G ++ E T + PS P + + G TV++ W P NG
Sbjct 586 SDLGVGVFTPTVEAC---TAQSTPSAPPQKVTCV----STGSTTVRVSWVPPPADSRNGI 638
Query 363 ILDYEVTLTRWKSHLQN------YTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVL 414
I Y V + + + + Y + VG +
Sbjct 639 ITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSP 698
Query 415 T-IPACDFQATHPVMDLKAFP-KDNMLWVEWTTP-----RESVKKYILEWCVLSDKAPCI 467
+ + + P ++ P + V W P ++ Y + + L + P
Sbjct 699 VLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRG 758
Query 468 TDWQQED--GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
Q+ T + G L Y ITV G G+ K PT+
Sbjct 759 QPIIQDVMLAEAQETTISG-LTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPGRPTM 817
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDSSHTEYTLSSLTS 584
+ A+L+W P G + Y + YR ++ +T++ L
Sbjct 818 MVSTTAMHTALLQWH--PPKELPGELLGYRLQYRRADEARPNTIDFGKDDQHFTVTGLHK 875
Query 585 DTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGV 637
Y+ R+AA G + E TTP+ A P L T
Sbjct 876 GATYIFRLAAKNRAGPGEEFEKEITTPEDAPS-----GFPQNLRVTGLTTSTT 923
Score = 203 bits (516), Expect = 3e-52, Method: Composition-based stats.
Identities = 101/576 (18%), Positives = 164/576 (28%), Gaps = 50/576 (9%)
Query 63 NYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIIS 122
+ W +Q+ + SS T D+ + + L V+ T+ +
Sbjct 544 ELVYWAAED---EGQQHKVTFDPTSSYTLEDLK-PDTLYHFQLAARSDLGVGVFTPTVEA 599
Query 123 ----GLPPEKPKNLSCIVNEGKKMRCEWDGGRET---HLETNFTLKSE--WATHKFADCK 173
P P+ ++C+ +R W + T +++ E +
Sbjct 600 CTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVV 659
Query 174 AKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVIN 232
S + VWV A +G S + V PP + V
Sbjct 660 DGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEP 719
Query 233 SEELSSILKLTWTNPSIK--SVIILKYNIQY-RTKDASTWSQIPPEDTASTRSS-FTVQD 288
S+ + ++W P I Y + Y R ++ Q +D + T+
Sbjct 720 LN--STAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTISG 777
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
L P T Y + G G S T P + T T
Sbjct 778 LTPETTYSITVAAYTTKGDGARSK---PKVVTTTGAVPGRPTMMV------STTAMHTAL 828
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQN-----YTVNATKLTVNLTNDRYLATLTVR 403
L W PP E G++L Y + R N +T Y+ L +
Sbjct 829 LQWH--PPKELPGELLGYRLQYRRADEARPNTIDFGKDDQHFTVTGLHKGATYIFRLAAK 886
Query 404 NLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTP-RESVKKYILEWCVLS 461
N G + I + + +L+ + + W P I + V+
Sbjct 887 NRAGPGEEFEKEITTPEDAPSGFPQNLRVTGLTTSTTELAWDPPVLAERNGRITNYTVVY 946
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPS 520
+ Q G VH T L L Y I V + G G SI++
Sbjct 947 RDINSQHELQNVTGDVHLTLL--GLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPMEQV 1004
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLS 580
R K +L W+ + I Y N +V VD ++
Sbjct 1005 FAKNFRVAAAMKTSVLLSWEVPDSYKSAVP---FKILY-----NGQSVEVDGHSMRKLIA 1056
Query 581 SLTSDTLYMVRMAAY-TDEGGKDGPEFTFTTPKFAQ 615
L +T Y + T GG T P
Sbjct 1057 DLQPNTEYSFVLMNRGTSAGGLQHLVSIRTAPDLLP 1092
Score = 129 bits (325), Expect = 4e-29, Method: Composition-based stats.
Identities = 75/487 (15%), Positives = 128/487 (26%), Gaps = 49/487 (10%)
Query 69 TNHFTIPKEQYTIINRTASSVTFTDI---ASLNIQLTCNILTFGQLEQNVYGITIISGLP 125
+ + I+R SS + + + + E + + +P
Sbjct 649 VDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVP 708
Query 126 PEKPKNLSCIVNEGKKMRCEWDG-------GRETHLETNFTLKSEWATHKFADCKAKRDT 178
P+ + + W G+ + + +
Sbjct 709 SGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLA 768
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
T + V A G S V P +++ S
Sbjct 769 EAQETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAV----PGRPTMMVSTTAM 824
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
L W P +L Y +QYR D + + I D FTV L Y+F
Sbjct 825 HTALLQWHPPKELPGELLGYRLQYRRADEARPNTI---DFGKDDQHFTVTGLHKGATYIF 881
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
R+ G G E T ED PS P + + L W
Sbjct 882 RLAAKNRAGPGEEF----EKEITTPEDAPSGFPQNLRVTGLTTSTTE----LAWDPPVLA 933
Query 358 EANGKILDYEVTLT--RWKSHLQNYTVNATKLTVNL-TNDRYLATLTVRNLVGKSD-AAV 413
E NG+I +Y V + LQN T + + L + Y + G +
Sbjct 934 ERNGRITNYTVVYRDINSQHELQNVTGDVHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPS 993
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR--ESVKKYILEWCVLSDKAPCITDWQ 471
+ + A + + W P +S + + + S
Sbjct 994 IQSRTMPMEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQS---------V 1044
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
+ DG R L +L + Y + G + P + +K
Sbjct 1045 EVDGHSMR-KLIADLQPNTEYSFVLMNRGTSAGGLQHLVSIRT-------APDLLPQKPL 1096
Query 532 KNEAVLE 538
A +E
Sbjct 1097 PASAFIE 1103
>sp|A2A8L5|PTPRF_MOUSE Receptor-type tyrosine-protein phosphatase
F OS=Mus musculus OX=10090 GN=Ptprf PE=1 SV=1
Length=1898
Score = 272 bits (696), Expect = 7e-75, Method: Composition-based stats.
Identities = 114/607 (19%), Positives = 202/607 (33%), Gaps = 71/607 (12%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A ++LG + + K P PP +L V +E ++ + LTW + + + Y I
Sbjct 300 AISSLGMIEATA---QVTVKALPKPPIDLVV--TETTATSVTLTWDSG--NTEPVSFYGI 352
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
QYR Q E + +++ L PF+EY FR+ + G+G SE
Sbjct 353 QYRAAGTDGPFQ---EVDGVASTRYSIGGLSPFSEYAFRVLAVNSIGRG---PPSEAVRA 406
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR------- 372
T E PS P + + T+ + W+ PP E NG + Y V T
Sbjct 407 RTGEQAPSSPP----RRVQARMLSASTMLVQWE--PPEEPNGLVRGYRVYYTPDSRRPLS 460
Query 373 -WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDL 430
W H + + T + L Y + VG + + + P
Sbjct 461 AWHKHNTDAGLLTT-VGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQ 519
Query 431 KAFPKDNMLWVEWT-TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
D + + W P+E + KY L + D+ + +Y +L
Sbjct 520 ANAESDTRIQLSWLLPPQERIVKYELVYWAAEDEGQQ----HKVTFDPTSSYTLEDLKPD 575
Query 490 KCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQ 547
Y + G G +++A Q+ PS P V G + W P D +
Sbjct 576 TLYHFQLAARSDLGVGVFTPTVEARTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSR 635
Query 548 NGFIRNYTIFYRTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
NG I Y++ Y + G + +V H+ + L L T Y V + A+TD G G
Sbjct 636 NGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVG--PG 693
Query 604 PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHI 663
PE + P + + + P + + K VP+ I
Sbjct 694 PESS---PVLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLP---------VPNKQHGQI 741
Query 664 AQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEG 723
+ N + Q + V + + S + T
Sbjct 742 RGYQVTYVRLENGEPRGQ-------PIIQDVMLAEAQETTI-----SGLTPETTYSITVA 789
Query 724 HSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSV-----QVFS 778
+ G + + + + + S+T ++ ++ ++P +
Sbjct 790 AYTTKGDGARSKPKVVTTTGAVPGRPTMMVSTTAMHTALLQWHPPKELPGELLGYRLQYR 849
Query 779 RSESTQP 785
R++ +P
Sbjct 850 RADEARP 856
Score = 238 bits (606), Expect = 2e-63, Method: Composition-based stats.
Identities = 106/556 (19%), Positives = 186/556 (33%), Gaps = 50/556 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P +P + +++ W + + + L WA PTS
Sbjct 511 VPAQPADFQANAESDTRIQLSWLLPPQERI-VKYELVY-WAAEDEGQQHKVTFDPTSSYT 568
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ A + LG + P+ P V S+ ++++W
Sbjct 569 LEDLKPDTLYHFQLAARSDLGVGVFTPTVEARTAQSTPSAP-PQKVTCVSTGSTTVRVSW 627
Query 245 TNP--SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
P ++ II +Y++ Y D + + + SS+ + L+ +TEY +R
Sbjct 628 VPPPADSRNGIITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAH 687
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
+ G G S T ED PS P +++P V + WK P + +G+
Sbjct 688 TDVGPGPESS---PVLVRTDEDVPSGPP-RKVEVEP---LNSTAVHVSWKLPVPNKQHGQ 740
Query 363 ILDYEVTLTRWKSHLQNYT----------VNATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
I Y+VT R ++ T ++ Y T+ G +
Sbjct 741 IRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARS 800
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITD 469
+ + + + ++W P + Y L++ + P D
Sbjct 801 KPKVVTTTGAVPGRPTMMVSTTAMHTALLQWHPPKELPGELLGYRLQYRRADEARPNTID 860
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK-GPTVRTK 528
+ ++D T L + Y+ + GPG + + PS +R
Sbjct 861 FGKDDQHFTVT----GLHKGATYVFRLAAKNRAGPGEEFEKEITTPEDVPSGFPQNLRVT 916
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLY 588
+ + L WD + +NG I NYT+ YR I NV ++ T TL L DT Y
Sbjct 917 GLTTSTTELTWDPPVLAERNGHITNYTVVYRDINSQLELQNV-TNDTHLTLLGLKPDTTY 975
Query 589 MVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLI 647
+++ A+T +G P T ++ A V A + LL
Sbjct 976 DIKVRAHTSKGAGPLSPSIQSRT--MPVEQVFAKNFRVAAAMKTSVLLSW---------- 1023
Query 648 KKHIWPNVPDPSKSHI 663
VPD KS +
Sbjct 1024 ------EVPDSYKSAV 1033
Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats.
Identities = 96/533 (18%), Positives = 169/533 (32%), Gaps = 42/533 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRET-HLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P P+ + + M +W+ E L + + + + K +T
Sbjct 413 PSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLL 472
Query 184 VDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
++ + + V A A+G + P P + E + ++L
Sbjct 473 TTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQANA--ESDTRIQL 530
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
+W P I+KY + Y + + T SS+T++DLKP T Y F++
Sbjct 531 SWLLP--PQERIVKYELVYWAAEDEGQQH---KVTFDPTSSYTLEDLKPDTLYHFQLAAR 585
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
+ G G ++ E T + PS P + + G TV++ W P NG
Sbjct 586 SDLGVGVFTPTVE---ARTAQSTPSAPPQKVTCV----STGSTTVRVSWVPPPADSRNGI 638
Query 363 ILDYEVTLTRWKSHLQN------YTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVL 414
I Y V + + + + Y + VG +
Sbjct 639 ITQYSVAYEAVDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSP 698
Query 415 T-IPACDFQATHPVMDLKAFP-KDNMLWVEWTTP-----RESVKKYILEWCVLSDKAPCI 467
+ + + P ++ P + V W P ++ Y + + L + P
Sbjct 699 VLVRTDEDVPSGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRG 758
Query 468 TDWQQED--GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
Q+ T + G L Y ITV G G+ K PT+
Sbjct 759 QPIIQDVMLAEAQETTISG-LTPETTYSITVAAYTTKGDGARSKPKVVTTTGAVPGRPTM 817
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDSSHTEYTLSSLTS 584
+ A+L+W P G + Y + YR ++ +T++ L
Sbjct 818 MVSTTAMHTALLQWH--PPKELPGELLGYRLQYRRADEARPNTIDFGKDDQHFTVTGLHK 875
Query 585 DTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGV 637
Y+ R+AA G + E TTP+ P L T
Sbjct 876 GATYVFRLAAKNRAGPGEEFEKEITTPEDVPS-----GFPQNLRVTGLTTSTT 923
Score = 200 bits (508), Expect = 2e-51, Method: Composition-based stats.
Identities = 98/576 (17%), Positives = 163/576 (28%), Gaps = 50/576 (9%)
Query 63 NYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIIS 122
+ W +Q+ + SS T D+ + + L V+ T+ +
Sbjct 544 ELVYWAAED---EGQQHKVTFDPTSSYTLEDLK-PDTLYHFQLAARSDLGVGVFTPTVEA 599
Query 123 ----GLPPEKPKNLSCIVNEGKKMRCEWDGGRET---HLETNFTLKSE--WATHKFADCK 173
P P+ ++C+ +R W + T +++ E +
Sbjct 600 RTAQSTPSAPPQKVTCVSTGSTTVRVSWVPPPADSRNGIITQYSVAYEAVDGEDRKRHVV 659
Query 174 AKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVIN 232
S + VWV A +G S + V PP + V
Sbjct 660 DGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEP 719
Query 233 SEELSSILKLTWTNPSIK--SVIILKYNIQY-RTKDASTWSQIPPEDTASTRSS-FTVQD 288
S+ + ++W P I Y + Y R ++ Q +D + T+
Sbjct 720 LN--STAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAEAQETTISG 777
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
L P T Y + G G S T P + T T
Sbjct 778 LTPETTYSITVAAYTTKGDGARSK---PKVVTTTGAVPGRPTMMV------STTAMHTAL 828
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQN-----YTVNATKLTVNLTNDRYLATLTVR 403
L W PP E G++L Y + R N +T Y+ L +
Sbjct 829 LQWH--PPKELPGELLGYRLQYRRADEARPNTIDFGKDDQHFTVTGLHKGATYVFRLAAK 886
Query 404 NLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTP-RESVKKYILEWCVLS 461
N G + I + + +L+ + + W P +I + V+
Sbjct 887 NRAGPGEEFEKEITTPEDVPSGFPQNLRVTGLTTSTTELTWDPPVLAERNGHITNYTVVY 946
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPS 520
+ Q H T L L Y I V + G G SI++
Sbjct 947 RDINSQLELQNVTNDTHLTLL--GLKPDTTYDIKVRAHTSKGAGPLSPSIQSRTMPVEQV 1004
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLS 580
R K +L W+ + I Y N +V VD ++
Sbjct 1005 FAKNFRVAAAMKTSVLLSWEVPDSYKSAVP---FKILY-----NGQSVEVDGHSMRKLIA 1056
Query 581 SLTSDTLYMVRMAAY-TDEGGKDGPEFTFTTPKFAQ 615
L +T Y + + GG T P
Sbjct 1057 DLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPDLLP 1092
Score = 133 bits (334), Expect = 3e-30, Method: Composition-based stats.
Identities = 78/487 (16%), Positives = 128/487 (26%), Gaps = 49/487 (10%)
Query 69 TNHFTIPKEQYTIINRTASSVTFTDI---ASLNIQLTCNILTFGQLEQNVYGITIISGLP 125
+ + I+R SS + + + + E + + +P
Sbjct 649 VDGEDRKRHVVDGISREHSSWDLLGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVP 708
Query 126 PEKPKNLSCIVNEGKKMRCEWDG-------GRETHLETNFTLKSEWATHKFADCKAKRDT 178
P+ + + W G+ + + +
Sbjct 709 SGPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLA 768
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
T + V A G S V P +++ S
Sbjct 769 EAQETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTGAV----PGRPTMMVSTTAM 824
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
L W P +L Y +QYR D + + I D FTV L YVF
Sbjct 825 HTALLQWHPPKELPGELLGYRLQYRRADEARPNTI---DFGKDDQHFTVTGLHKGATYVF 881
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
R+ G G E T ED PS P + + L W
Sbjct 882 RLAAKNRAGPGEEF----EKEITTPEDVPSGFPQNLRVTGLTTSTTE----LTWDPPVLA 933
Query 358 EANGKILDYEVTLTRWKSHLQNYTV-NATKLTVNLTN--DRYLATLTVRNLVGKSD-AAV 413
E NG I +Y V S L+ V N T LT+ Y + G +
Sbjct 934 ERNGHITNYTVVYRDINSQLELQNVTNDTHLTLLGLKPDTTYDIKVRAHTSKGAGPLSPS 993
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR--ESVKKYILEWCVLSDKAPCITDWQ 471
+ + A + + W P +S + + + S
Sbjct 994 IQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQS---------V 1044
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
+ DG R L +L + Y + + G + P + +K
Sbjct 1045 EVDGHSMR-KLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRT-------APDLLPQKPL 1096
Query 532 KNEAVLE 538
A +E
Sbjct 1097 PASAFIE 1103
>sp|P10586|PTPRF_HUMAN Receptor-type tyrosine-protein phosphatase
F OS=Homo sapiens OX=9606 GN=PTPRF PE=1 SV=2
Length=1907
Score = 272 bits (696), Expect = 7e-75, Method: Composition-based stats.
Identities = 120/615 (20%), Positives = 207/615 (34%), Gaps = 78/615 (13%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A ++LG + + K P PP +L V +E ++ + LTW + S + Y I
Sbjct 300 AISSLGMIEATA---QVTVKALPKPPIDLVV--TETTATSVTLTWDSG--NSEPVTYYGI 352
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
QYR Q E + +++ L PF+EY FR+ + G+G SE
Sbjct 353 QYRAAGTEGPFQ---EVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRG---PPSEAVRA 406
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR------- 372
T E PS P + + T+ + W+ PP E NG + Y V T
Sbjct 407 RTGEQAPSSPP----RRVQARMLSASTMLVQWE--PPEEPNGLVRGYRVYYTPDSRRPPN 460
Query 373 -WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDL 430
W H + + T + L Y + VG + + + P
Sbjct 461 AWHKHNTDAGLLTT-VGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQ 519
Query 431 KAFPKDNMLWVEWT-TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
D + + W P+E + Y L + D+ + +Y +L
Sbjct 520 AEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQ----HKVTFDPTSSYTLEDLKPD 575
Query 490 KCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQ 547
Y + G G +I+A Q+ PS P V +G + W P D +
Sbjct 576 TLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSR 635
Query 548 NGFIRNYTIFYRTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
NG I Y++ Y + G + +V H+ + L L T Y V + A+TD G G
Sbjct 636 NGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVG--PG 693
Query 604 PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHI 663
PE + P + + + P + + + K VP I
Sbjct 694 PESS---PVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLP---------VPSKQHGQI 741
Query 664 AQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKP-FPEDLKSLDLFKKEKINTE 722
+ N + + V + +P ED ++ + E
Sbjct 742 RGYQVTYVRLENGEPRG-------LPIIQDVMLAEAQWRPEESEDYETTIS----GLTPE 790
Query 723 GHSSGIGGSSCMSS----SRPSISSSDENESSQNT---SSTVQYSTVVHSGYRHQVPSV- 774
S + S+P I ++ + T S+T + ++ ++P
Sbjct 791 TTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGEL 850
Query 775 ----QVFSRSESTQP 785
+ R++ +P
Sbjct 851 LGYRLQYCRADEARP 865
Score = 229 bits (583), Expect = 1e-60, Method: Composition-based stats.
Identities = 103/566 (18%), Positives = 190/566 (34%), Gaps = 61/566 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P +P + V +++ W +E + WA PTS
Sbjct 511 VPAQPADFQAEVESDTRIQLSWLLPPQERIIMYEL---VYWAAEDEDQQHKVTFDPTSSY 567
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
+ A + +G + P+ P V+ S+ ++++
Sbjct 568 TLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAP-PQKVMCVSMGSTTVRVS 626
Query 244 WTNP--SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
W P ++ +I +Y++ Y D + + + SS+ + L+ +TEY +R
Sbjct 627 WVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRA 686
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ G G S T ED PS P +++P V + WK P + +G
Sbjct 687 HTDVGPGPESS---PVLVRTDEDVPSGPP-RKVEVEP---LNSTAVHVYWKLPVPSKQHG 739
Query 362 KILDYEVTLTRWKSHL-------------------QNYTVNATKLTVNLTNDRYLATLTV 402
+I Y+VT R ++ + T ++ Y T+
Sbjct 740 QIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAA 799
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCV 459
G + I + + N ++W P + Y L++C
Sbjct 800 YTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCR 859
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
+ P D+ ++D T L + Y+ + G G + + P
Sbjct 860 ADEARPNTIDFGKDDQHFTVT----GLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLP 915
Query 520 SK-GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
S + + + L WD + +NG I +YT+ +R I + N+ ++ T +T
Sbjct 916 SGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNI-TTDTRFT 974
Query 579 LSSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGV 637
L+ L DT Y +++ A+T +G P T ++ A V A + LL
Sbjct 975 LTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRT--MPVEQVFAKNFRVAAAMKTSVLLSW 1032
Query 638 LFCFNKRDLIKKHIWPNVPDPSKSHI 663
VPD KS +
Sbjct 1033 ----------------EVPDSYKSAV 1042
Score = 223 bits (569), Expect = 8e-59, Method: Composition-based stats.
Identities = 93/521 (18%), Positives = 170/521 (33%), Gaps = 46/521 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRET-HLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P P+ + + M +W+ E L + + + + + K +T
Sbjct 413 PSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLL 472
Query 184 VDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
++ + + V A A+G + P P + E + ++L
Sbjct 473 TTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAE--VESDTRIQL 530
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
+W P I+ Y + Y + + T SS+T++DLKP T Y F++
Sbjct 531 SWLLP--PQERIIMYELVYWAAEDEDQQH---KVTFDPTSSYTLEDLKPDTLYRFQLAAR 585
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
+ G G + + T + PS P + + G TV++ W P NG
Sbjct 586 SDMGVGVF---TPTIEARTAQSTPSAPPQKVMCV----SMGSTTVRVSWVPPPADSRNGV 638
Query 363 ILDYEVTLT------RWKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVL 414
I Y V R + + + + + Y + VG +
Sbjct 639 ITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSP 698
Query 415 T-IPACDFQATHPVMDLKAFP-KDNMLWVEWTTP-----RESVKKYILEWCVLSDKAPC- 466
+ + + P ++ P + V W P ++ Y + + L + P
Sbjct 699 VLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRG 758
Query 467 ----------ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
W+ E+ + T + G L Y +TV G G+ K
Sbjct 759 LPIIQDVMLAEAQWRPEESEDYETTISG-LTPETTYSVTVAAYTTKGDGARSKPKIVTTT 817
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDSSHT 575
PT+ N A+L+W P G + Y + Y R ++
Sbjct 818 GAVPGRPTMMISTTAMNTALLQWH--PPKELPGELLGYRLQYCRADEARPNTIDFGKDDQ 875
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
+T++ L T Y+ R+AA G + E TP+
Sbjct 876 HFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPS 916
Score = 188 bits (477), Expect = 2e-47, Method: Composition-based stats.
Identities = 98/590 (17%), Positives = 162/590 (27%), Gaps = 65/590 (11%)
Query 63 NYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIIS 122
+ W +Q+ + SS T D+ + + + V+ TI +
Sbjct 544 ELVYWAAED---EDQQHKVTFDPTSSYTLEDLK-PDTLYRFQLAARSDMGVGVFTPTIEA 599
Query 123 ----GLPPEKPKNLSCIVNEGKKMRCEWDG-------GRETHLETNF-TLKSEWATHKFA 170
P P+ + C+ +R W G T + + E
Sbjct 600 RTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVV 659
Query 171 DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLS 229
D ++ + + VWV A +G S + V PP +
Sbjct 660 DGISREHSSWDLVG---LEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVE 716
Query 230 VINSEELSSILKLTWT--NPSIKSVIILKYNIQY-RTKDASTWSQIPPEDT--------- 277
V S+ + + W PS + I Y + Y R ++ +D
Sbjct 717 VEPLN--STAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRP 774
Query 278 -ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
S T+ L P T Y + G G S T P +
Sbjct 775 EESEDYETTISGLTPETTYSVTVAAYTTKGDGARSK---PKIVTTTGAVPGRP------T 825
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN-----YTVNATKLTVNL 391
T T L W PP E G++L Y + R N +T
Sbjct 826 MMISTTAMNTALLQWH--PPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLH 883
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTP-RES 449
Y+ L +N G + I + + +L + + W P
Sbjct 884 KGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAE 943
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PE 508
I+ + V+ + Q T + L Y I V + G G
Sbjct 944 RNGRIISYTVVFRDINSQQELQNI--TTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSP 1001
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV 568
SI++ R K +L W+ + I Y N +V
Sbjct 1002 SIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVP---FKILY-----NGQSV 1053
Query 569 NVDSSHTEYTLSSLTSDTLYMVRMAAY-TDEGGKDGPEFTFTTPKFAQGE 617
VD ++ L +T Y + + GG T P +
Sbjct 1054 EVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPDLLPHK 1103
>sp|P97527|CNTN5_RAT Contactin-5 OS=Rattus norvegicus OX=10116
GN=Cntn5 PE=1 SV=1
Length=1099
Score = 268 bits (685), Expect = 2e-74, Method: Composition-based stats.
Identities = 93/458 (20%), Positives = 160/458 (35%), Gaps = 32/458 (7%)
Query 207 VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA 266
S + + + P PP VI E S L+W+ + I YN+Q R+ +
Sbjct 656 ADSVSDEAELLVRGPPGPPG--VVIVEEITESTATLSWSPATDNHSPISSYNLQARSPFS 713
Query 267 STWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
W + PE S DL P+ EY FR+ G G S S T E
Sbjct 714 LGWQTVKTVPEVITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSIPS--RMIRTNEA 771
Query 325 RPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQNYTV 382
P APS + S G R + + W+ + NG+ Y V + + V
Sbjct 772 VPKTAPS-----NVSGGSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMV 826
Query 383 NATKLTVNLTND-------RYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDLKAFP 434
++ + + D + + V N G + ++ I + + + T D+ A
Sbjct 827 TSSDASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPTAAPTDVTATS 886
Query 435 KD-NMLWVEWTTPRESV---KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
+ ++V W +ES+ + + + + D P + + L
Sbjct 887 VSVSEIFVVWKHVKESLGRPQGFEIGYW--KDTEPEDSAETVRTRGNESFVMLTGLEGDT 944
Query 491 CYLITVTPVYADGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y +TV G G P + A K+ PPS+ P + ++ L W+ +
Sbjct 945 LYHLTVRAYNGAGYGPPSREVSATTKRHPPSEPPGNLRWEQQGSQVSLGWEPVRPLANES 1004
Query 550 FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT 609
+ Y +FYR + V + + L +Y++ + AY EGG
Sbjct 1005 EVMGYKVFYRQEG--HSKGQVIETQKPQAVVPLPEAGVYIIEVRAY-SEGGDGTASSQIR 1061
Query 610 TPKFAQGEI-EAIVVPVCLAFLLTTLLGVLFCFNKRDL 646
P +A G+I A L+ + L +
Sbjct 1062 VPSYAGGKITSAQSTLHSLSKWSSVTLLLALMLPSSSW 1099
Score = 124 bits (310), Expect = 1e-27, Method: Composition-based stats.
Identities = 65/450 (14%), Positives = 130/450 (29%), Gaps = 51/450 (11%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKS----EWATHKFADC 172
++ PP P + W + H +++ L++
Sbjct 663 AELLVRGPPGPPGVVIVEEITESTATLSWSPATDNHSPISSYNLQARSPFSLGWQTVKTV 722
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD--HINFDPVYKVKPNPPHNLSV 230
+ +V E V A N +G V P N V
Sbjct 723 PEVITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSIPSRMIRTNEAVPKTAPSN--V 780
Query 231 INSEELSSILKLTWTN--PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
L + W ++ Y + +R W + + +++ + +
Sbjct 781 SGGSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSDASKFIYRDES 840
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
+ P T + ++ G G + S+ + E P+ AP+ S +
Sbjct 841 VPPLTPFEVKVGVYNNKGDGPF---SQIVVICSAEGEPTAAPTDVTATSVS----VSEIF 893
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK---------LTVNLTNDRYLAT 399
+VWK + E+ G+ +E+ WK + + LT + Y T
Sbjct 894 VVWKHV--KESLGRPQGFEIGY--WKDTEPEDSAETVRTRGNESFVMLTGLEGDTLYHLT 949
Query 400 LTVRNLVGKSDAAVLTIPACDFQATH-PVMDLKAFPKDNMLWVEWTTPRE-----SVKKY 453
+ N G + P +L+ + + + + W R V Y
Sbjct 950 VRAYNGAGYGPPSREVSATTKRHPPSEPPGNLRWEQQGSQVSLGWEPVRPLANESEVMGY 1009
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
+ + + + Q+ V L E+ Y+I V G G+ S
Sbjct 1010 KVFYRQEGHSKGQVIETQKPQAVV-------PLPEAGVYIIEVRAYSEGGDGTASSQIR- 1061
Query 514 LKQAPPS-KGPTVRTKKVGKNEAVLEWDQL 542
PS G + + + + +W +
Sbjct 1062 ----VPSYAGGKITSAQSTLHSLS-KWSSV 1086
Score = 92.6 bits (228), Expect = 9e-18, Method: Composition-based stats.
Identities = 54/334 (16%), Positives = 96/334 (29%), Gaps = 21/334 (6%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN---FTLKSEWATHKFADCKA 174
I +P P N+S ++ W+ E + + + K
Sbjct 766 IRTNEAVPKTAPSNVSGGSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKM 825
Query 175 KRDTPTSCTVDYSTVY--FVNIEVWVEAENALGKVTSDHINFDPVYKVKP-NPPHNLSVI 231
+ S + EV V N G I + +P P +++
Sbjct 826 VTSSDASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPTAAPTDVTAT 885
Query 232 NSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ S + + W + + I Y KD T S + L+
Sbjct 886 SVSV--SEIFVVWKHVKESLGRPQGFEIGY-WKDTEPEDSAETVRTRGNESFVMLTGLEG 942
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
T Y +R G G S E S T PS+ P + Q V L W
Sbjct 943 DTLYHLTVRAYNGAGYG---PPSREVSATTKRHPPSEPP-----GNLRWEQQGSQVSLGW 994
Query 352 KTLPPFEANGKILDYEVTLT-RWKSHLQNYTVNATKLTVNLTN-DRYLATLTVRNLVGKS 409
+ + P +++ Y+V S Q + V L Y+ + + G
Sbjct 995 EPVRPLANESEVMGYKVFYRQEGHSKGQVIETQKPQAVVPLPEAGVYIIEVRAYSEGGDG 1054
Query 410 --DAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
+ + + T L + K + + +
Sbjct 1055 TASSQIRVPSYAGGKITSAQSTLHSLSKWSSVTL 1088
>sp|O94779|CNTN5_HUMAN Contactin-5 OS=Homo sapiens OX=9606 GN=CNTN5
PE=1 SV=2
Length=1100
Score = 268 bits (684), Expect = 3e-74, Method: Composition-based stats.
Identities = 87/429 (20%), Positives = 160/429 (37%), Gaps = 31/429 (7%)
Query 207 VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA 266
S + + + P PP + V E S L+W+ + I YN+Q R+ +
Sbjct 656 ADSVSDEAELLVRGPPGPPGIVIVE--EITESTATLSWSPAADNHSPISSYNLQARSPFS 713
Query 267 STWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
W + PE S DL P+ EY FR+ G G S S T E
Sbjct 714 LGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPS--RMIRTNEA 771
Query 325 RPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQNYTV 382
P AP+ + S G R + + W+ + NG+ Y V + + V
Sbjct 772 VPKTAPT-----NVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMV 826
Query 383 NATKLTVNLTND-------RYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDLKAFP 434
+++ + + D + + V N G + ++ I + + + + D+KA
Sbjct 827 TSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATS 886
Query 435 KD-NMLWVEWTTPRESV---KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
+ + V W +ES+ + + + + ++ T + + L +
Sbjct 887 VSVSEILVAWKHIKESLGRPQGFEVGYWKDMEQE--DTAETVKTRGNESFVILTGLEGNT 944
Query 491 CYLITVTPVYADGPGSPES-IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y TV G G P S + A K++PPS+ P+ + ++ L W+ +
Sbjct 945 LYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWEQQGSQVSLGWEPVIPLANES 1004
Query 550 FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT 609
+ Y +FYR + + V + + L +Y++ + AY EGG
Sbjct 1005 EVVGYKVFYRQEGHSNS--QVIETQKLQAVVPLPDAGVYIIEVRAY-SEGGDGTASSQIR 1061
Query 610 TPKFAQGEI 618
P ++ G+I
Sbjct 1062 VPSYSGGKI 1070
Score = 130 bits (326), Expect = 2e-29, Method: Composition-based stats.
Identities = 63/417 (15%), Positives = 123/417 (29%), Gaps = 44/417 (11%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKS----EWATHKFADC 172
++ PP P + W + H +++ L++
Sbjct 663 AELLVRGPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTV 722
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV--TSDHINFDPVYKVKPNPPHNLSV 230
+ +V E V A N +G ++ V P N V
Sbjct 723 PEIITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTN--V 780
Query 231 INSEELSSILKLTWTN--PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
L + W ++ Y + +R W + + +++ + +
Sbjct 781 SGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDES 840
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
+ P T + ++ G G + S+ + E PS AP+ S +
Sbjct 841 VPPLTPFEVKVGVYNNKGDGPF---SQIVVICSAEGEPSAAPTDVKATSVS----VSEIL 893
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK---------LTVNLTNDRYLAT 399
+ WK + E+ G+ +EV WK Q T K LT N Y T
Sbjct 894 VAWKHI--KESLGRPQGFEVGY--WKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFT 949
Query 400 LTVRNLVGKSDAAV-LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE-----SVKKY 453
+ N G + ++ + +L+ + + + + W V Y
Sbjct 950 VRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWEQQGSQVSLGWEPVIPLANESEVVGY 1009
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
+ + + + Q+ V L ++ Y+I V G G+ S
Sbjct 1010 KVFYRQEGHSNSQVIETQKLQAVV-------PLPDAGVYIIEVRAYSEGGDGTASSQ 1059
Score = 60.3 bits (144), Expect = 8e-08, Method: Composition-based stats.
Identities = 36/207 (17%), Positives = 57/207 (28%), Gaps = 20/207 (10%)
Query 113 QNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEW-----DGGRETHLETNFTLKSEWATH 167
+ I G P P ++ ++ W GR E + +
Sbjct 863 SQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRPQGFEVGY---WKDMEQ 919
Query 168 KFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN-PPH 226
+ K S + V A N G K P+ P
Sbjct 920 EDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPS 979
Query 227 NLSVINSEELSSILKLTWTN--PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
NL E+ S + L W P ++ Y + YR + S + + +
Sbjct 980 NLR---WEQQGSQVSLGWEPVIPLANESEVVGYKVFYRQEGHS-----NSQVIETQKLQA 1031
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWS 311
V L Y+ +R E G G S
Sbjct 1032 VVP-LPDAGVYIIEVRAYSEGGDGTAS 1057
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 43/232 (19%), Positives = 68/232 (29%), Gaps = 34/232 (15%)
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG------NETAVN 569
+ PP V +++ ++ A L W P + I +Y + R+
Sbjct 668 RGPPGPPGIVIVEEITESTATLSWS--PAADNHSPISSYNLQARSPFSLGWQTVKTVPEI 725
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD--GPEFTFTT----PKFAQGEIEAIVV 623
+ L Y R+ A G D P T PK A +
Sbjct 726 ITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSG 785
Query 624 ----------PVCLAFLLTTLLGVLFCFN---KRDLIKKHIWPNVPDPSKSHIAQWSPHT 670
PV F G + F R K+ + V S
Sbjct 786 RRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGW-KEKM---VTSSEASKFIYRDESV 841
Query 671 PPRHNFNSKDQMY---SDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKI 719
PP F K +Y DG F+ + V+ + P D+K+ + E +
Sbjct 842 PPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEIL 893
>sp|Q9JM58|CRLF1_MOUSE Cytokine receptor-like factor 1 OS=Mus
musculus OX=10090 GN=Crlf1 PE=1 SV=1
Length=425
Score = 252 bits (643), Expect = 6e-74, Method: Composition-based stats.
Identities = 95/369 (26%), Positives = 147/369 (40%), Gaps = 27/369 (7%)
Query 29 GYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASS 88
ISP+ P + + S+ A C + D A + W N +P E ++N + +
Sbjct 44 AVISPQDPTLLIGSSLQATCSIHG---DTPGATAEGLYWTLNGRRLPSELSRLLNTSTLA 100
Query 89 VTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG 148
+ ++ Q N++ + + G + GLPPEKP N+SC K + C W
Sbjct 101 LALANLNGSRQQSGDNLVCHARDGSILAGSCLYVGLPPEKPFNISCWSRNMKDLTCRWTP 160
Query 149 GR--ETHLETNFTLKSE--WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
G ET L TN++LK + W + P SC + F E+WVEA N L
Sbjct 161 GAHGETFLHTNYSLKYKLRWYGQDNTCEEYHTVGPHSCHIPKDLALFTPYEIWVEATNRL 220
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW-TNPSIKSVIIL-KYNIQYR 262
G SD + D + V +PP ++ V L L + W + P++K + KY I+YR
Sbjct 221 GSARSDVLTLDVLDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYR 280
Query 263 TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC-----MKEDGKGYWSDWSEEA 317
+D+ W + D S ++S + LKP T Y ++RC G WS+WS
Sbjct 281 VEDSVDWKVV---DDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPT 337
Query 318 SGITYEDR---PSKAPSFWYKIDPSHTQGYRTV--QLVWKTLPPFEANGKILDYEVT--L 370
+ T P +PS R + L W A L + +
Sbjct 338 AASTPRSERPGPGGGVCEPRGGEPSSGPVRRELKQFLGW---LKKHAYCSNLSFRLYDQW 394
Query 371 TRWKSHLQN 379
W
Sbjct 395 RAWMQKSHK 403
Score = 59.5 bits (142), Expect = 7e-08, Method: Composition-based stats.
Identities = 28/146 (19%), Positives = 52/146 (36%), Gaps = 5/146 (3%)
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
Y L++ + + + H ++ +LA Y I V G + +
Sbjct 171 NYSLKYKLRWYGQDNTCE-EYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLT 229
Query 512 AYLKQAPPS-KGPTVRTKKVG--KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETA 567
+ + P V +VG +++ + W P F Y I YR +
Sbjct 230 LDVLDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKV 289
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMA 593
V+ S+ T L+ L T+Y V++
Sbjct 290 VDDVSNQTSCRLAGLKPGTVYFVQVR 315
Score = 38.7 bits (88), Expect = 0.25, Method: Composition-based stats.
Identities = 18/97 (19%), Positives = 29/97 (30%), Gaps = 7/97 (7%)
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI-RNYTIFY--RTIIGNET--AVNVD 571
PP K + + W P F+ NY++ Y R + T +
Sbjct 136 LPPEKPFNISCWSRNMKDLTCRW--TPGAHGETFLHTNYSLKYKLRWYGQDNTCEEYHTV 193
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
H+ + L T Y + + A G T
Sbjct 194 GPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTL 230
>sp|P97528|CNTN6_RAT Contactin-6 OS=Rattus norvegicus OX=10116
GN=Cntn6 PE=1 SV=1
Length=1028
Score = 265 bits (678), Expect = 9e-74, Method: Composition-based stats.
Identities = 116/643 (18%), Positives = 213/643 (33%), Gaps = 69/643 (11%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
VVQ+ + + C K I WK + + + + S+ ++
Sbjct 420 VVQVGGDISIEC--KPNAFPKAS-----ISWKRGTENLKQSK-RVFFLEDGSLKICNVTR 471
Query 97 LNI-QLTC---NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRET 152
+ TC N G+ ++ P P + V E + C+ +
Sbjct 472 SDAGSYTCVATNQFGNGKSSGSLIVKERTVITVP--PSKMDVTVGESIVLPCQ-----VS 524
Query 153 HLETNFTLKSEWATHKFADCKAKRDTPTSC---------TVDYSTVYFVNIEVWVEAENA 203
H T L + D K + + V+
Sbjct 525 HDPTMEVLFVWYFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLGHSGKYLCTVQTT-- 582
Query 204 LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT 263
+ D + + P PP ++ V + +S +L+W + I + IQ RT
Sbjct 583 ---LERLSAVADIIVRGPPGPPEDVKVEHISSTTS--QLSWRPGPDNNSPIQIFTIQTRT 637
Query 264 KDASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+ W + PE + TV L P+ EY FR+ G G S SE T
Sbjct 638 PFSVGWQAVATVPEILNGQTYNATVIGLSPWVEYEFRVVAGNNIGIGEPSKPSELLR--T 695
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN- 379
P+ AP ++ + G R+ + + W+ +P NG+ Y + S
Sbjct 696 KASIPNVAP-----VNINGGGGSRSELVITWEPIPEELQNGEGFGYIIMFRPVGSTTWMK 750
Query 380 ---YTVNATKLTVN----LTNDRYLATLTVRNLVGKSDAAVLTI--PACDFQATHP-VMD 429
V ++K + + + V N G+ + ++I D P
Sbjct 751 EKVALVESSKFIYRNESIMPLSPFEVKVGVYNNEGEGSLSTVSIVYSGEDEPRLAPRGTS 810
Query 430 LKAFPKDNMLW----VEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+++F +M + W V Y + + + K I + G V + G
Sbjct 811 VQSFSASDMEVSWNAIAWNRNTGRVLGYEVLYWTDNSKESMIGKI-RVSGNVTTKNITG- 868
Query 486 LAESKCYLITVTPVYADGPGSPES-IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
L + Y +V G G + K++PPS+ P K+ ++ L W+ +
Sbjct 869 LRANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLSNSKLCLNWEHVKT 928
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
+ Y I YR ++T V ++ + L D Y++ + +GG
Sbjct 929 MENESEVLGYKILYRQNRQSKTHVLETNNTSAELLVPFEED--YLIEIR-TVSDGGDGSS 985
Query 605 EFTFTTPKFAQ-GEIEAIVVPVCLAFLLTTLLGVLFCFNKRDL 646
PK + + ++ FL T++G +CF + L
Sbjct 986 SEEIRIPKMSSLSSVGVQILKPSTQFL--TMVGFFYCFVIQPL 1026
>sp|Q9JMB8|CNTN6_MOUSE Contactin-6 OS=Mus musculus OX=10090 GN=Cntn6
PE=1 SV=2
Length=1028
Score = 265 bits (678), Expect = 1e-73, Method: Composition-based stats.
Identities = 113/642 (18%), Positives = 208/642 (32%), Gaps = 67/642 (10%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
VVQ+ + + C K I WK + + + ++ S+ ++
Sbjct 420 VVQVGGDISIEC--KPNAFPKAS-----ISWKRGTENLKQSK-RVLFLEDGSLKICNVTR 471
Query 97 LNI-QLTC---NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRET 152
+ TC N G+ + P P + V E + C+ +
Sbjct 472 ADAGSYTCVATNQFGNGKSSGGLVVKERTIITVP--PSKMDVTVGESIVLPCQ-----VS 524
Query 153 HLETNFTLKSEWATHKFADCKAKRDTPTSC---------TVDYSTVYFVNIEVWVEAENA 203
H T L + D K + + V+
Sbjct 525 HDPTMEVLFVWYFNGDIIDLKKGVAHFERIGGESVGDLMIRNIQLGHSGKYLCTVQTT-- 582
Query 204 LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT 263
+ D + + P PP ++ V + +S +L+W + I + IQ RT
Sbjct 583 ---LERLSAVADIIVRGPPGPPEDVKVEHISSTTS--QLSWRPGPDNNSPIQIFTIQTRT 637
Query 264 KDASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+ W + PE + TV L P+ EY FR+ G G S SE T
Sbjct 638 PFSVGWQAVATVPEILNGQTYNATVVGLSPWVEYEFRVVAGNNIGIGEPSKPSELLR--T 695
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN- 379
P+ AP + + G R+ + + W+ +P NG+ Y V +
Sbjct 696 KASVPNVAP-----GNINGGGGSRSELVITWEAIPEELQNGEGFGYIVMFRPVGTTAWMK 750
Query 380 ---YTVNATKLTVN----LTNDRYLATLTVRNLVGKSDAAVLTIP---ACDFQATHPVMD 429
V ++K + + + V N G+ + +TI + Q
Sbjct 751 ERVALVESSKFIYRNESIMPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTS 810
Query 430 LKAFPKDNMLW----VEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+++F M + W V Y + + + K I + G V + G
Sbjct 811 VQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDNSKESMIGKI-RVSGNVTTKNITG- 868
Query 486 LAESKCYLITVTPVYADGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
L + Y +V G G + K++PPS+ P K+ ++ L W+ +
Sbjct 869 LRANTIYFASVRAYNTAGTGPSSLPVNVTTKKSPPSQPPANIAWKLSNSKLCLNWEHVKT 928
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
+ Y I YR ++T + ++ + L D Y++ + +GG
Sbjct 929 MENESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFEED--YLIEIR-TVSDGGDGSS 985
Query 605 EFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDL 646
PK + + + +++GV +CF L
Sbjct 986 SEEIRIPKMSSLSSTGVQISKPSTQ-SLSMVGVFYCFAIHPL 1026
>sp|P68500|CNTN5_MOUSE Contactin-5 OS=Mus musculus OX=10090 GN=Cntn5
PE=1 SV=2
Length=1098
Score = 266 bits (679), Expect = 1e-73, Method: Composition-based stats.
Identities = 91/458 (20%), Positives = 160/458 (35%), Gaps = 32/458 (7%)
Query 207 VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA 266
S + + + P PP VI E S L+W+ + I YN+Q R+ +
Sbjct 655 ADSVSDEAELLVRGPPGPPG--VVIVEEITESTATLSWSPATDNHSPISSYNLQARSPFS 712
Query 267 STWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
W + PE S DL P+ EY FR+ G G S S T E
Sbjct 713 LGWQTVKTVPEVITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSIPS--RMIRTNEA 770
Query 325 RPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQNYTV 382
P APS + S G R + + W+ + NG+ Y V + + V
Sbjct 771 VPKTAPS-----NVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMV 825
Query 383 NATKLTVNLTND-------RYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDLKAFP 434
+++ + + D + + V N G + ++ I + + + T D+ A
Sbjct 826 TSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPTAAPTDVTATS 885
Query 435 KD-NMLWVEWTTPRESV---KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
+ ++V W +ES+ + + + + D P + + L +
Sbjct 886 VSVSEIFVVWKHVKESLGRPQGFEISYW--KDTEPEDSVETVRTRGNESFVMLTGLEGNT 943
Query 491 CYLITVTPVYADGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y +TV G G P K+ PP + P + ++ L W+ +
Sbjct 944 LYHLTVRAYNGAGYGPPSREASTTTKRHPPREPPGNLRWEQQGSQVSLGWEPVRPLANES 1003
Query 550 FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT 609
+ Y +FYR +E V + + L +Y++ + AY EGG
Sbjct 1004 EVMGYKVFYRQEGHSEG--QVIETQKPQAVVPLPEAGVYIIEVRAY-SEGGDGTASSQIR 1060
Query 610 TPKFAQGEI-EAIVVPVCLAFLLTTLLGVLFCFNKRDL 646
P ++ G+I A L+ + L +
Sbjct 1061 VPSYSGGKITSAQSTLHSLSKWSSVTLLLALMLPSSSW 1098
Score = 128 bits (322), Expect = 6e-29, Method: Composition-based stats.
Identities = 67/450 (15%), Positives = 132/450 (29%), Gaps = 51/450 (11%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKS----EWATHKFADC 172
++ PP P + W + H +++ L++
Sbjct 662 AELLVRGPPGPPGVVIVEEITESTATLSWSPATDNHSPISSYNLQARSPFSLGWQTVKTV 721
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD--HINFDPVYKVKPNPPHNLSV 230
+ +V E V A N +G V P N V
Sbjct 722 PEVITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSIPSRMIRTNEAVPKTAPSN--V 779
Query 231 INSEELSSILKLTWTN--PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
L + W ++ Y + +R W + + +++ + +
Sbjct 780 SGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDES 839
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
+ P T + ++ G G + S+ + E P+ AP+ S +
Sbjct 840 VPPLTPFEVKVGVYNNKGDGPF---SQIVVICSAEGEPTAAPTDVTATSVS----VSEIF 892
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK---------LTVNLTNDRYLAT 399
+VWK + E+ G+ +E++ WK +V + LT N Y T
Sbjct 893 VVWKHV--KESLGRPQGFEISY--WKDTEPEDSVETVRTRGNESFVMLTGLEGNTLYHLT 948
Query 400 LTVRNLVGKSDAAVLTIPACDFQAT-HPVMDLKAFPKDNMLWVEWTTPRE-----SVKKY 453
+ N G + P +L+ + + + + W R V Y
Sbjct 949 VRAYNGAGYGPPSREASTTTKRHPPREPPGNLRWEQQGSQVSLGWEPVRPLANESEVMGY 1008
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
+ + + + Q+ V L E+ Y+I V G G+ S
Sbjct 1009 KVFYRQEGHSEGQVIETQKPQAVV-------PLPEAGVYIIEVRAYSEGGDGTASSQIR- 1060
Query 514 LKQAPPS-KGPTVRTKKVGKNEAVLEWDQL 542
PS G + + + + +W +
Sbjct 1061 ----VPSYSGGKITSAQSTLHSLS-KWSSV 1085
Score = 96.1 bits (237), Expect = 7e-19, Method: Composition-based stats.
Identities = 54/334 (16%), Positives = 97/334 (29%), Gaps = 21/334 (6%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN---FTLKSEWATHKFADCKA 174
I +P P N+S ++ W+ E + + + K
Sbjct 765 IRTNEAVPKTAPSNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKM 824
Query 175 KRDTPTSCTVDYSTVY--FVNIEVWVEAENALGKVTSDHINFDPVYKVKP-NPPHNLSVI 231
+ S + EV V N G I + +P P +++
Sbjct 825 VTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPTAAPTDVTAT 884
Query 232 NSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ S + + W + + I Y KD + T S + L+
Sbjct 885 SVSV--SEIFVVWKHVKESLGRPQGFEISY-WKDTEPEDSVETVRTRGNESFVMLTGLEG 941
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
T Y +R G G S EAS T P + P + Q V L W
Sbjct 942 NTLYHLTVRAYNGAGYG---PPSREASTTTKRHPPREPP-----GNLRWEQQGSQVSLGW 993
Query 352 KTLPPFEANGKILDYEVTLT-RWKSHLQNYTVNATKLTVNLTN-DRYLATLTVRNLVGKS 409
+ + P +++ Y+V S Q + V L Y+ + + G
Sbjct 994 EPVRPLANESEVMGYKVFYRQEGHSEGQVIETQKPQAVVPLPEAGVYIIEVRAYSEGGDG 1053
Query 410 --DAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
+ + + T L + K + + +
Sbjct 1054 TASSQIRVPSYSGGKITSAQSTLHSLSKWSSVTL 1087
Score = 52.2 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 42/230 (18%), Positives = 66/230 (29%), Gaps = 34/230 (15%)
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG------NETAVN 569
+ PP V +++ ++ A L W P + I +Y + R+
Sbjct 667 RGPPGPPGVVIVEEITESTATLSWS--PATDNHSPISSYNLQARSPFSLGWQTVKTVPEV 724
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD--GPEFTFTT----PKFAQGEIEAIVV 623
+ L Y R+ A G D P T PK A +
Sbjct 725 ITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSIPSRMIRTNEAVPKTAPSNVSGRSG 784
Query 624 ----------PVCLAFLLTTLLGVLFCFN---KRDLIKKHIWPNVPDPSKSHIAQWSPHT 670
PV F G + F R K+ + V S
Sbjct 785 RRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGW-KEKM---VTSSEASKFIYRDESV 840
Query 671 PPRHNFNSKDQMY---SDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKE 717
PP F K +Y DG F+ + V+ + P D+ + + E
Sbjct 841 PPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPTAAPTDVTATSVSVSE 890
>sp|O75462|CRLF1_HUMAN Cytokine receptor-like factor 1 OS=Homo
sapiens OX=9606 GN=CRLF1 PE=1 SV=1
Length=422
Score = 250 bits (638), Expect = 3e-73, Method: Composition-based stats.
Identities = 94/369 (25%), Positives = 147/369 (40%), Gaps = 27/369 (7%)
Query 29 GYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASS 88
ISP+ P + + S+ A C + D A + W N +P E ++N + +
Sbjct 41 AVISPQDPTLLIGSSLLATCSVHG---DPPGATAEGLYWTLNGRRLPPELSRVLNASTLA 97
Query 89 VTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG 148
+ ++ + N++ + + G + GLPPEKP N+SC K + C W
Sbjct 98 LALANLNGSRQRSGDNLVCHARDGSILAGSCLYVGLPPEKPVNISCWSKNMKDLTCRWTP 157
Query 149 GR--ETHLETNFTLKSE--WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
G ET L TN++LK + W + P SC + F E+WVEA N L
Sbjct 158 GAHGETFLHTNYSLKYKLRWYGQDNTCEEYHTVGPHSCHIPKDLALFTPYEIWVEATNRL 217
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW-TNPSIKSVIIL-KYNIQYR 262
G SD + D + V +PP ++ V L L + W + P++K + KY I+YR
Sbjct 218 GSARSDVLTLDILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYR 277
Query 263 TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC-----MKEDGKGYWSDWSEEA 317
+D+ W + D S ++S + LKP T Y ++RC G WS+WS
Sbjct 278 VEDSVDWKVV---DDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPT 334
Query 318 SGITYEDR---PSKAPSFWYKIDPSHTQGYRTV--QLVWKTLPPFEANGKILDYEVT--L 370
+ T P +PS R + L W A L + +
Sbjct 335 AASTPRSERPGPGGGACEPRGGEPSSGPVRRELKQFLGW---LKKHAYCSNLSFRLYDQW 391
Query 371 TRWKSHLQN 379
W
Sbjct 392 RAWMQKSHK 400
Score = 59.5 bits (142), Expect = 7e-08, Method: Composition-based stats.
Identities = 28/146 (19%), Positives = 52/146 (36%), Gaps = 5/146 (3%)
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
Y L++ + + + H ++ +LA Y I V G + +
Sbjct 168 NYSLKYKLRWYGQDNTCE-EYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLT 226
Query 512 AYLKQAPPS-KGPTVRTKKVG--KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETA 567
+ + P V +VG +++ + W P F Y I YR +
Sbjct 227 LDILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKV 286
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMA 593
V+ S+ T L+ L T+Y V++
Sbjct 287 VDDVSNQTSCRLAGLKPGTVYFVQVR 312
Score = 39.1 bits (89), Expect = 0.20, Method: Composition-based stats.
Identities = 18/106 (17%), Positives = 30/106 (28%), Gaps = 7/106 (7%)
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI-RNYTIFY--RTIIGNET--AVNVD 571
PP K + + W P F+ NY++ Y R + T +
Sbjct 133 LPPEKPVNISCWSKNMKDLTCRW--TPGAHGETFLHTNYSLKYKLRWYGQDNTCEEYHTV 190
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
H+ + L T Y + + A G T +
Sbjct 191 GPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDILDVVTTD 236
>sp|Q5VTT5|MYOM3_HUMAN Myomesin-3 OS=Homo sapiens OX=9606 GN=MYOM3
PE=1 SV=1
Length=1437
Score = 264 bits (673), Expect = 4e-72, Method: Composition-based stats.
Identities = 126/626 (20%), Positives = 209/626 (33%), Gaps = 92/626 (15%)
Query 43 NFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLT 102
F+ C+ E +D A I W + + + + +TD + +++++
Sbjct 287 PFSLSCLFSEDVLD-----AESIQWFRDGSLLRSSRR-------RKILYTDRQA-SLKVS 333
Query 103 CNI------------LTFGQLEQNVYGITI--ISGLP--PEKPKNLSCIVNEGKKMRCEW 146
C FG EQ+ Y + + P P P N+ C+ + W
Sbjct 334 CTYKEDEGLYMVRVPSPFGPREQSTYVLVRDAEAENPGAPGSPLNVRCLDVNRDCLILTW 393
Query 147 DGGRET--HLETNFTL-KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENA 203
+T + T +T+ + + + ++ C C + + V A +
Sbjct 394 APPSDTRGNPITAYTIERCQGESGEWIACHEAPGGTCRCPIQGLVEG-QSYRFRVRAISR 452
Query 204 LGKVTSDH------------------INFDP------------VYKVKPNPPHNLSVINS 233
+G I FD P+PP N V S
Sbjct 453 VGSSVPSKASELVVMGDHDAARRKTEIPFDLGNKITISTDAFEDTVTIPSPPTN--VHAS 510
Query 234 EELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
E + + L W PS + L Y+++ + TW I E + F V DL+
Sbjct 511 EIREAYVVLAWEEPSPRDRAPLTYSLEKSVIGSGTWEAISSESPVRS-PRFAVLDLEKKK 569
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
YVFR+R M + G SD SE + I P+ P TQ +V L W
Sbjct 570 SYVFRVRAMNQYGL---SDPSEPSEPIALRGPPATLPPPAQVQAFRDTQ--TSVSLTWDP 624
Query 354 LPPFEANG-KILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNL----VGK 408
+ E G I +V + W++ + N + T+ TV VR++ VG+
Sbjct 625 VKDPELLGYYIYSRKVGTSEWQT-VNNKPIQGTRFTVPGLRTGKEYEFCVRSVSEAGVGE 683
Query 409 SDAAVLTIPACDF---QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAP 465
S AA I + L K N + + W P+ IL + L
Sbjct 684 SSAATEPIRVKQALATPSAPYGFALLNCGK-NEMVIGWKPPKRRGGGKILGYF-LDQHDS 741
Query 466 CITDWQ--QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG---SPESIKAYLKQAPPS 520
DW + R +L E Y G G +P S+ + P
Sbjct 742 EELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQ 801
Query 521 KGPT--VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS--SHTE 576
GP VR +V VL+W+ P+ + G + Y + ++ + S T
Sbjct 802 PGPPYDVRASEVRATSLVLQWEP-PLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTH 860
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKD 602
+S L Y+ ++ A G
Sbjct 861 LRVSDLQPGKSYVFQVQAMNSAGLGQ 886
Score = 149 bits (376), Expect = 2e-35, Method: Composition-based stats.
Identities = 83/462 (18%), Positives = 141/462 (31%), Gaps = 49/462 (11%)
Query 126 PEKPKNLSCIVNEGKKMRCEWD-GGRETHLETNFTL-KSEWATHKFADCKAKRDTPTSCT 183
P P N+ + W+ ++L KS + + ++ +
Sbjct 501 PSPPTNVHASEIREAYVVLAWEEPSPRDRAPLTYSLEKSVIGSGTWEAISSESPVRSPRF 560
Query 184 VDYSTVYFVNIEVWVEAENALG----KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ V A N G S+ I P PP + + +
Sbjct 561 AVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLP-PPAQVQAFR--DTQTS 617
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ LTW +L Y I R S W + + + FTV L+ EY F +
Sbjct 618 VSLTWDPVKDPE--LLGYYIYSRKVGTSEWQTVN--NKPIQGTRFTVPGLRTGKEYEFCV 673
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
R + E G G S +E PS F G + + WK P
Sbjct 674 RSVSEAGVGESSAATEPIRVKQALATPSAPYGFALL-----NCGKNEMVIGWKP-PKRRG 727
Query 360 NGKILDYEV----TLTRWKSHLQNYTVNATKLTVNLTNDR--YLATLTVRNLVG----KS 409
GKIL Y + + + + V+ ++ Y N G +
Sbjct 728 GGKILGYFLDQHDSEELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGELSA 787
Query 410 DAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCIT 468
+++ P D++A + L ++W P + + V +
Sbjct 788 PSSLFECKEWTMPQPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQ 847
Query 469 DWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
G + T+LR +L K Y+ V + + G G P P+ P +
Sbjct 848 WKPVTPGPISGTHLRVSDLQPGKSYVFQVQAMNSAGLGQPS---------MPTD-PVLLE 897
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
K G +E + D+ GFI Y F + +
Sbjct 898 DKPGAHEIEVGVDE------EGFI--YLAFEAPEAPDSSEFQ 931
Score = 98.4 bits (243), Expect = 2e-19, Method: Composition-based stats.
Identities = 56/385 (15%), Positives = 97/385 (25%), Gaps = 61/385 (16%)
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y+ R+ G S + E AP + + L W
Sbjct 343 YMVRV--PSPFGPREQSTY---VLVRDAEAENPGAPGSPLNVR-CLDVNRDCLILTWAPP 396
Query 355 PPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT------NDRYLATLTVRNLVGK 408
N I Y + + +S A T Y + + VG
Sbjct 397 SDTRGN-PITAYTIERCQGESGEWIACHEAPGGTCRCPIQGLVEGQSYRFRVRAISRVGS 455
Query 409 SDAA------------------------------VLTIPACDFQATHPVMDLKAFP-KDN 437
S + P ++ A ++
Sbjct 456 SVPSKASELVVMGDHDAARRKTEIPFDLGNKITISTDAFEDTVTIPSPPTNVHASEIREA 515
Query 438 MLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
+ + W P Y LE V+ E + +L + K Y+
Sbjct 516 YVVLAWEEPSPRDRAPLTYSLEKSVIGSGTWEAIS--SESPVRSPRFAVLDLEKKKSYVF 573
Query 495 TVTPVYADGPG----SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
V + G E I A V+ + + L WD +
Sbjct 574 RVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRDTQTSVSLTWDPVKDPE---- 629
Query 551 IRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
+ Y I+ R + +E T N T +T+ L + Y + + ++ G +
Sbjct 630 LLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFCVRSVSEAGVGES--SAA 687
Query 609 TTPKFAQGEIEAIVVPVCLAFLLTT 633
T P + + P A L
Sbjct 688 TEPIRVKQALATPSAPYGFALLNCG 712
>sp|Q810U4|NRCAM_MOUSE Neuronal cell adhesion molecule OS=Mus
musculus OX=10090 GN=Nrcam PE=1 SV=2
Length=1256
Score = 261 bits (667), Expect = 1e-71, Method: Composition-based stats.
Identities = 103/430 (24%), Positives = 159/430 (37%), Gaps = 49/430 (11%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYR--TKDASTWSQIP 273
P+Y V PNPP +L + N +L ++LTWT + I K+ I+Y DA W
Sbjct 636 PIYDV-PNPPFDLELTN--QLDKSVQLTWTPGDDNNSPITKFIIEYEDAMHDAGLWRHQA 692
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
T + L P+ Y FR+ G+ S+ SE+ +T P + P
Sbjct 693 EVSGTQTTAQL---KLSPYVNYSFRVMAENSIGRSMPSEASEQ--YLTKAAEPDQNPMAV 747
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT------RWKS----HLQNYTVN 383
+ + + WK L F++NG L Y+V+ W S ++ Y V+
Sbjct 748 EGL----GTEPDNLVITWKPLNGFQSNGPGLQYKVSWRQKDGDDEWTSVVVANVSKYIVS 803
Query 384 ATKLTVNLTNDRYLATLTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
T V YL + N VG AAV+ D P + + V
Sbjct 804 GTPTFV-----PYLIKVQALNDVGFAPEPAAVMGHSGEDLPMVAPGNVRVSVVNSTLAEV 858
Query 442 EWTT-PRESVKKY-----ILEWCVLSDKAPCITDWQQEDGTVHRTYLRG---NLAESKCY 492
W P +SV+ + I W S +++ T T G L Y
Sbjct 859 HWDPVPPKSVRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGTKTHGMLPGLQPYSHY 918
Query 493 LITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
+ V V G G + + + + PS +++ + LEWD P NG +
Sbjct 919 ALNVRVVNGKGEGPASTDRGFHTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHPNGIL 976
Query 552 RNYTIFYRTI-----IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPE 605
Y + Y+ I +G + + ++ T +TL +L T Y A T G G E
Sbjct 977 TEYILQYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSVGPGSQITE 1036
Query 606 FTFTTPKFAQ 615
TT A
Sbjct 1037 EAITTVDEAG 1046
Score = 133 bits (335), Expect = 2e-30, Method: Composition-based stats.
Identities = 114/750 (15%), Positives = 208/750 (28%), Gaps = 119/750 (16%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRT-ASSV 89
++P++ V+ N T +C I W TN I + ++
Sbjct 359 VAPQNLVLSPGENGTLIC-------RANGNPKPRISWLTNGVPIEIALDDPSRKIDGDTI 411
Query 90 TFTDIASLN-IQLTCNILTFGQLEQNVYGITI---ISGLPPEKPKNLSC-------IVNE 138
F+++ + CN N YG + + E P+ L+ I N
Sbjct 412 IFSNVQESSSAVYQCNA-------SNKYGYLLANAFVNVLAEPPRILTSANTLYQVIANR 464
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
+ C + G + T K + D D T
Sbjct 465 PALLDCAFFGSP---MPTIEWFKGTKGSALHEDIYVLHDNGTLEIPVAQKDSTGTYT--C 519
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A N LG + V+ +P + + K+++ ++
Sbjct 520 VARNKLGMAK------NEVHLEIKDPTRIIKQPEYAVVQRGSKVSFECRVKHDHTLIPTI 573
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW----- 313
+ + E ++ + V D +DG Y
Sbjct 574 MWLKDNGELP----NDERFSTDKDHLVVSD------------VKDDDGGTYTCTANTTLD 617
Query 314 SEEASGITYEDRPSKAPSFWYKI-DPS-----HTQGYRTVQLVWKTLPPFEANGKILDYE 367
S AS + P+ P+ Y + +P Q ++VQL W P + N I +
Sbjct 618 SASASAVLRVVAPTPTPAPIYDVPNPPFDLELTNQLDKSVQLTW--TPGDDNNSPITKFI 675
Query 368 VTLTR-------WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
+ W+ + T Y + N +G+S + +
Sbjct 676 IEYEDAMHDAGLWRHQAEVSGTQTTAQLKLSPYVNYSFRVMAENSIGRSMPSEASEQYLT 735
Query 421 FQATHPVMDLKAFPKDNM---LWVEWTTPRE-SVKKYILEWCVLSDKAPCITDWQQEDGT 476
A + L + W L++ V + +W
Sbjct 736 KAAEPDQNPMAVEGLGTEPDNLVITWKPLNGFQSNGPGLQYKVSWRQKDGDDEWTSVVVA 795
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKVGKNE 534
Y+ YLI V + G P ++ + + P P VR V
Sbjct 796 NVSKYIVSGTPTFVPYLIKVQALNDVGFAPEPAAVMGHSGEDLPMVAPGNVRVSVVNSTL 855
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA---------VNVDSSHTEYTLSSLTSD 585
A + WD +P G ++ Y I+Y + + + T L L
Sbjct 856 AEVHWDPVPPKSVRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGTKTHGMLPGLQPY 915
Query 586 TLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
+ Y + + +G + F TP+ P L + TL
Sbjct 916 SHYALNVRVVNGKGEGPASTDRGFHTPEG------VPSAPSSLKIVNPTLDS-------- 961
Query 645 DLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPF 704
L + P+ P+ T + + + G D+ + +K
Sbjct 962 -LTLEWDPPSHPN---------GILTEYILQYQPINSTHELGPLVDLKI----PANK--T 1005
Query 705 PEDLKSLDLFKKEKINTEGHSSGIGGSSCM 734
LK+L+ + K +S GS
Sbjct 1006 RWTLKNLNFSTRYKFYFYAQTSVGPGSQIT 1035
>sp|Q92823|NRCAM_HUMAN Neuronal cell adhesion molecule OS=Homo
sapiens OX=9606 GN=NRCAM PE=1 SV=3
Length=1304
Score = 260 bits (664), Expect = 4e-71, Method: Composition-based stats.
Identities = 106/462 (23%), Positives = 168/462 (36%), Gaps = 58/462 (13%)
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY 257
V A L V PVY V PNPP +L + +++L ++L+WT + I K+
Sbjct 625 VSASAVLSVVAPTPTPA-PVYDV-PNPPFDLEL--TDQLDKSVQLSWTPGDDNNSPITKF 680
Query 258 NIQYRTKDAST--WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
I+Y W T + L P+ Y FR+ + GK S+ SE
Sbjct 681 IIEYEDAMHKPGLWHHQTEVSGTQTTAQL---KLSPYVNYSFRVMAVNSIGKSLPSEASE 737
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT---- 371
+ +T P K P+ + + + WK L FE+NG L Y+V+
Sbjct 738 Q--YLTKASEPDKNPTAVEGL----GSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDG 791
Query 372 --RWKS----HLQNYTVNATKLTVNLTNDRYLATLTVRNLVG--KSDAAVLTIPACDFQA 423
W S ++ Y V+ T V YL + N +G A V+ D
Sbjct 792 DDEWTSVVVANVSKYIVSGTPTFV-----PYLIKVQALNDMGFAPEPAVVMGHSGEDLPM 846
Query 424 THPVMDLKAFPKDNMLWVEWTT-PRESVKKY-----ILEWCVLSDKAPCITDWQQEDGTV 477
P + V W P +S++ + I W S +++ T
Sbjct 847 VAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTF 906
Query 478 HRTYLRG---NLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVGKN 533
+ G L Y + V V G G + + + PS +++ +
Sbjct 907 QGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLD 966
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTI-----IGNETAVNVDSSHTEYTLSSLTSDTLY 588
LEWD P NG + YT+ Y+ I +G + + ++ T +TL +L T Y
Sbjct 967 SLTLEWD--PPSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRY 1024
Query 589 MVRMAAYTDEG-GKDGPEFTFTT--------PKFAQGEIEAI 621
A T G G E TT P G+++A+
Sbjct 1025 KFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAGKVQAV 1066
Score = 177 bits (448), Expect = 5e-44, Method: Composition-based stats.
Identities = 133/796 (17%), Positives = 246/796 (31%), Gaps = 119/796 (15%)
Query 29 GYIS--PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINR-- 84
+I PE VVQ S + C +K + H + ++W ++ +P ++ +++
Sbjct 546 TWIVKQPEYAVVQRGSMVSFECKVK-----HDHTLSLTVLWLKDNRELPSDERFTVDKDH 600
Query 85 ------------TASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNL 132
T + V T + S++ +++ VY + P P +L
Sbjct 601 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDV-------PNPPFDL 653
Query 133 SCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTP-TSCTVDYSTVY 190
K ++ W G + + T F ++ E A HK + + T T
Sbjct 654 ELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSP 713
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS-VINSEELSSILKLTWTN--P 247
+VN V A N++GK + + K P N + V L +TW
Sbjct 714 YVNYSFRVMAVNSIGKSLPSEASEQYLTKAS-EPDKNPTAVEGLGSEPDNLVITWKPLNG 772
Query 248 SIKSVIILKYNIQYRTKDAS-TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ L+Y + +R KD W+ + + + + V F Y+ +++ + + G
Sbjct 773 FESNGPGLQYKVSWRQKDGDDEWTSVVVANVSK----YIVSGTPTFVPYLIKVQALNDMG 828
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
G + ED P AP + T + W +P G + Y
Sbjct 829 FAPEP---AVVMGHSGEDLPMVAPGNVRVNVVNSTLAE----VHWDPVPLKSIRGHLQGY 881
Query 367 EVTLTRWKSHLQNY---------TVNATKLTVNLTN----DRYLATLTVRNLVGKSDAAV 413
+ + +S + T +K L Y + V N G+ A+
Sbjct 882 RIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASP 941
Query 414 LTIPACDFQATHPVMDLKAF-PKDNMLWVEWTTPR---ESVKKYILEWCVLSDKAPCITD 469
+ LK P + L +EW P + +Y L++ ++
Sbjct 942 DRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPL 1001
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP--ESIKAYLKQA---PPSKGP- 523
+ + NL S Y + G GS E + +A PP G
Sbjct 1002 VDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAGILPPDVGAG 1061
Query 524 -----TVRTKKVGK----NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG--NETAVNVDS 572
R + A + W+ + N + + Y V+
Sbjct 1062 KVQAVNPRISNLTAAAAETYANISWEYEGPEHVN-----FYVEYGVAGSKEEWRKEIVNG 1116
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLT 632
S + + L L T Y VR+ A D G + T P A +++ + +
Sbjct 1117 SRSFFGLKGLMPGTAYKVRVGAVGDSGFVSSEDVFETGPAMASRQVDIATQGWFIGLMCA 1176
Query 633 T----LLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMY---SD 685
L+ ++ CF +R+ P + D
Sbjct 1177 VALLILILLIVCFIRRNK-----------------GGKYPVKEKEDAHADPEIQPMKEDD 1219
Query 686 GNFTDVSVVE----IEANDKKPFPEDLKSLDLFKKEKINTEG------HSSGIGGSSCMS 735
G F + S E ++ + P +K D EG G
Sbjct 1220 GTFGEYSDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGK 1279
Query 736 SSRPSISSSDENESSQ 751
+ ++ +E+
Sbjct 1280 KEKEPAEGNESSEAPS 1295
>sp|P97686|NRCAM_RAT Neuronal cell adhesion molecule OS=Rattus
norvegicus OX=10116 GN=Nrcam PE=1 SV=2
Length=1214
Score = 260 bits (663), Expect = 4e-71, Method: Composition-based stats.
Identities = 106/457 (23%), Positives = 169/457 (37%), Gaps = 52/457 (11%)
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY 257
V A L V P+Y V PNPP +L + N +L ++LTWT + I K+
Sbjct 625 VSASAVLRVVAPTPTPA-PIYDV-PNPPFDLELTN--QLDKSVQLTWTPGDDNNSPITKF 680
Query 258 NIQYR--TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
I+Y +A W T + L P+ Y FR+ G+ S+ SE
Sbjct 681 IIEYEDAMHEAGLWRHQAEVSGTQTTAQL---KLSPYVNYSFRVMAENSIGRSVPSEASE 737
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT---- 371
+ +T P + P+ + + + WK L F++NG L Y+V+
Sbjct 738 Q--YLTKAAEPDQNPTAVEGL----GTEPDNLVITWKPLNGFQSNGPGLQYKVSWRQKDG 791
Query 372 --RWKS----HLQNYTVNATKLTVNLTNDRYLATLTVRNLVG--KSDAAVLTIPACDFQA 423
W S ++ Y V+ T V YL + N VG AAV+ D
Sbjct 792 DDEWTSVVVANVSKYIVSGTPTFV-----PYLIKVQALNDVGFAPEPAAVMGHSGEDLPM 846
Query 424 THPVMDLKAFPKDNMLWVEWTT-PRESVKKY-----ILEWCVLSDKAPCITDWQQEDGTV 477
P + + W P +SV+ + I W S +++ T
Sbjct 847 VAPGNVRVSVVNSTLAEAHWDPVPPKSVRGHLQGYRIYYWKAQSSSKRNRRHIEKKILTF 906
Query 478 HRTYLRG---NLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVGKN 533
+ G L Y++ V V G G + + + + PS +++ +
Sbjct 907 QGSKTHGMLPGLQPYSHYVLNVRVVNGKGEGPASADRGFHTPEGVPSAPSSLKIVNPTLD 966
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTI-----IGNETAVNVDSSHTEYTLSSLTSDTLY 588
LEWD P NG + Y + Y+ I +G + + ++ T +TL +L T Y
Sbjct 967 SLTLEWD--PPSHPNGILTEYILKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRY 1024
Query 589 MVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVP 624
A T G G E TT +G+ I+ P
Sbjct 1025 KFYFYAQTSVGSGSQITEEAITT--VDEGKKAGILPP 1059
Score = 147 bits (370), Expect = 1e-34, Method: Composition-based stats.
Identities = 93/542 (17%), Positives = 175/542 (32%), Gaps = 65/542 (12%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSV--- 89
P VVQ S + C +K + H I+W ++ +P ++ +++ V
Sbjct 552 PGYAVVQRGSKVSFECKVK-----HDHTLIPTILWLKDNGELPNDERFSVDKDHLVVSDV 606
Query 90 ------TFT-----DIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNE 138
T+T + S++ ++ +Y + P P +L
Sbjct 607 KDEDGGTYTCAANTTLDSVSASAVLRVVAPTPTPAPIYDV-------PNPPFDLELTNQL 659
Query 139 GKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTP-TSCTVDYSTVYFVNIEV 196
K ++ W G + + T F ++ E A H+ + + + T T +VN
Sbjct 660 DKSVQLTWTPGDDNNSPITKFIIEYEDAMHEAGLWRHQAEVSGTQTTAQLKLSPYVNYSF 719
Query 197 WVEAENALGKVTSDHINFDPVYKVKPNPPHNLS-VINSEELSSILKLTWTN--PSIKSVI 253
V AEN++G+ + + K P N + V L +TW +
Sbjct 720 RVMAENSIGRSVPSEASEQYLTKAA-EPDQNPTAVEGLGTEPDNLVITWKPLNGFQSNGP 778
Query 254 ILKYNIQYRTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
L+Y + +R KD W+ + + + + V F Y+ +++ + + G
Sbjct 779 GLQYKVSWRQKDGDDEWTSVVVANVSK----YIVSGTPTFVPYLIKVQALNDVGFAPEP- 833
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR 372
G + ED P AP + T W +PP G + Y + +
Sbjct 834 --AAVMGHSGEDLPMVAPGNVRVSVVNSTLAEA----HWDPVPPKSVRGHLQGYRIYYWK 887
Query 373 WKSHLQNY-------------TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
+S + + L Y+ + V N G+ A+
Sbjct 888 AQSSSKRNRRHIEKKILTFQGSKTHGMLPGLQPYSHYVLNVRVVNGKGEGPASADRGFHT 947
Query 420 DFQATHPVMDLKAF-PKDNMLWVEWTTPR---ESVKKYILEWCVLSDKAPCITDWQQEDG 475
LK P + L +EW P + +YIL++ ++ +
Sbjct 948 PEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYILKYQPINSTHELGPLVDLKIP 1007
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL----KQAPPSKGPTVRTKKVG 531
+ NL S Y + G GS + +A + P V K
Sbjct 1008 ANKTRWTLKNLNFSTRYKFYFYAQTSVGSGSQITEEAITTVDEGKKAGILPPDVGAGKAM 1067
Query 532 KN 533
+
Sbjct 1068 AS 1069
>sp|P23468|PTPRD_HUMAN Receptor-type tyrosine-protein phosphatase
delta OS=Homo sapiens OX=9606 GN=PTPRD PE=1 SV=2
Length=1912
Score = 260 bits (665), Expect = 6e-71, Method: Composition-based stats.
Identities = 92/407 (23%), Positives = 150/407 (37%), Gaps = 38/407 (9%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
K P PP V +E ++ + LTW + + Y IQ++ K++ ++
Sbjct 316 QITVKALPKPPGTPVV--TESTATSITLTWDSG--NPEPVSYYIIQHKPKNSE---ELYK 368
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
E + ++V L P+++Y FR+ + G+G SE T E PS AP
Sbjct 369 EIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRG---PPSEPVLTQTSEQAPSSAPRDV- 424
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR-WKSHLQNYTVNA------TKL 387
+ T+ + WK P E NG+I Y V T H+ N+ + T +
Sbjct 425 ---QARMLSSTTILVQWKE--PEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTI 479
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTP 446
+ Y + +G + ++ KA P + + + WT P
Sbjct 480 GNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPP 539
Query 447 RESVK-KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
R Y L + Q+ +Y L + Y + G G
Sbjct 540 RSDTIANYELVYKDGEHGEE-----QRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLG 594
Query 506 SP-ESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
+ I A Q+ PS P + ++ W PV+ QNG I Y+I Y + G
Sbjct 595 ASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDG 654
Query 564 NETAVN----VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
+ + + S T+Y L L T Y + + A+TD G GPE
Sbjct 655 EDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVG--PGPES 699
Score = 219 bits (557), Expect = 3e-57, Method: Composition-based stats.
Identities = 119/814 (15%), Positives = 256/814 (31%), Gaps = 96/814 (12%)
Query 23 ELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTII 82
+ + +P ++ S+ T + KE + + + T +
Sbjct 411 QTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTM-DPTQHVNNWMKH 469
Query 83 NRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIIS----GLPPEKPKNLSCIVNE 138
N S +T + +L F + I G+ P +P N
Sbjct 470 NVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGV-PGQPLNFKAEPES 528
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
+ W R + + + + + T + +
Sbjct 529 ETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLY-YFRLAA 587
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP--SIKSVIILK 256
+ LG T++ I+ + PP ++S + S+ + ++W P ++ II +
Sbjct 588 RSPQGLGASTAE-ISARTMQSKPSAPPQDISCTSP--SSTSILVSWQPPPVEKQNGIITE 644
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y+I+Y D S + + ++ L+ +TEY + + G G S
Sbjct 645 YSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESL---S 701
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
T ED PS P K++ +V++ W++ P + +G+I Y+V R ++
Sbjct 702 VLIRTNEDVPSGPP---RKVEVEAVNST-SVKVSWRSPVPNKQHGQIRGYQVHYVRMENG 757
Query 377 LQ-------------------NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
+ T + ++ Y T+T G + +
Sbjct 758 EPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLV 817
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPR---ESVKKYILEWCVLSDKAPCITDWQQED 474
+ + + N ++W P ++ Y L++ + ++ +++
Sbjct 818 STTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKE 877
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK-GPTVRTKKVGKN 533
T + + Y+ ++ G G + + + P+ + ++
Sbjct 878 DHFTATDIH----KGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTST 933
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVR 591
L W + +NG I YT+ YR I + + T TL+ L DT Y V+
Sbjct 934 SVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVK 993
Query 592 MAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKH 650
+ A+T +G P F T ++ A V + LL
Sbjct 994 VRAHTSKGPGPYSPSVQFRTLPVD--QVFAKNFHVKAVMKTSVLLSW------------- 1038
Query 651 IWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKS 710
+P+ S + P + +++ DG T +V ++ F
Sbjct 1039 ---EIPENYNSAM----PFKILYDDGKMVEEV--DGRATQKLIVNLKPEKSYSF------ 1083
Query 711 LDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQ 770
+ G+S+G + + P + + + + +
Sbjct 1084 -------VLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANEN 1136
Query 771 VPS------VQVFSRSESTQPLLDSEERPEDLQL 798
+ SR + +P E P++++L
Sbjct 1137 IKGYYIIIVPLKKSRGKFIKPW----ESPDEMEL 1166
Score = 213 bits (543), Expect = 1e-55, Method: Composition-based stats.
Identities = 104/600 (17%), Positives = 190/600 (32%), Gaps = 59/600 (10%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
I P + + + CV Y+ W + E I R +V
Sbjct 240 IPPTNHEIMPGGSVNITCV-------AVGSPMPYVKWMLGAEDLTPEDDMPIGR---NVL 289
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIIS-GLPPEKPKNLSCIVNEGKKMRCEWDGG 149
+ + TC ++ + + + IT+ + PP P + + WD G
Sbjct 290 ELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPV---VTESTATSITLTWDSG 346
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-T 208
++ + + K T+ + + E V A N +G+
Sbjct 347 NPE--PVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPP 404
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST 268
S+ + + + P ++ S+ + + W P + I Y + Y T D +
Sbjct 405 SEPVLTQTSEQAPSSAPRDVQARML--SSTTILVQWKEPEEPNGQIQGYRV-YYTMDPTQ 461
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
+ + T+ +L P Y ++ G G S + IT P +
Sbjct 462 HVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSS---DIQVITQTGVPGQ 518
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT-RWKSHLQNYTV---NA 384
+F + + ++ L W I +YE+ Q T+ +
Sbjct 519 PLNFK-----AEPESETSILLSWTPPRSDT----IANYELVYKDGEHGEEQRITIEPGTS 569
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAAV-LTIPACDFQATHPVMDLK-AFPKDNMLWVE 442
+L N Y L R+ G + ++ + + P D+ P + V
Sbjct 570 YRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVS 629
Query 443 WTTPRESVKKYIL-EWCVLS---DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
W P + I+ E+ + D + YL L + Y ITVT
Sbjct 630 WQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTA 689
Query 499 VYADGPGSPE-SIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
GPG S+ + PS P V + V + W + Q+G IR Y +
Sbjct 690 HTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQV 749
Query 557 FYRTIIGNETAVNV---------------DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
Y + E D++ + +S L +T Y + + AYT +G
Sbjct 750 HYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDG 809
Score = 58.7 bits (140), Expect = 3e-07, Method: Composition-based stats.
Identities = 54/358 (15%), Positives = 106/358 (30%), Gaps = 47/358 (13%)
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ------------ 348
C+ + G S S + + + P P+ + RT
Sbjct 98 CVASNNVGEIS-VSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPE 156
Query 349 LVW----KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRN 404
+ W + NG+I L A ++ + +D+ N
Sbjct 157 ITWFKDFLPVDTSNNNGRIKQ----LRSESIGGTPI-RGALQIEQSEESDQGKYECVATN 211
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR------ESVKKYILEWC 458
G +A + + + V + P N + + S Y+ +W
Sbjct 212 SAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYV-KWM 270
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ ++ D ++ +S Y T V G E+I +A
Sbjct 271 LGAEDLTPEDDM----PIGRNVLELNDVRQSANY----TCVAMSTLGVIEAIAQITVKAL 322
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS-SHTEY 577
P T + L WD + + Y I ++ E +D + T Y
Sbjct 323 PKPPGTPVVTESTATSITLTWDSGNPE----PVSYYIIQHKPKNSEELYKEIDGVATTRY 378
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT-----TPKFAQGEIEAIVVPVCLAFL 630
+++ L+ + Y R+ A + G E T P A +++A ++ +
Sbjct 379 SVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILV 436
>sp|A4IFW2|PTPRF_DANRE Receptor-type tyrosine-protein phosphatase
F OS=Danio rerio OX=7955 GN=ptprf PE=2 SV=1
Length=1909
Score = 259 bits (662), Expect = 1e-70, Method: Composition-based stats.
Identities = 97/424 (23%), Positives = 160/424 (38%), Gaps = 43/424 (10%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A ++LG + + K P PP +L+V +E ++ + LTW + + Y I
Sbjct 301 AISSLGMIEATA---QVSVKALPKPPTSLTV--TETTATSVTLTWDSG--NPEPVSYYII 353
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
QYR K + T Q E + +++ L P++EY FR+ + G+G SE
Sbjct 354 QYRAKTSDTNFQ---EVDGVATTRYSIGGLSPYSEYEFRVMAVNNIGRG---PPSEPVET 407
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR------- 372
T E PS P + T+ + W+ PP E NG+I Y + T
Sbjct 408 RTGEQAPSSPPLHV----QARMLSASTMLVQWE--PPEEPNGQIRGYRIYYTSDLDAPLS 461
Query 373 -WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDL 430
W+ H + + T ++ T Y + VG + VL + P
Sbjct 462 AWQKHNTDDSRLTT-ISSLTTGITYSLRVLGFTSVGDGPPSDVLQVKTQQGVPAQPSSFE 520
Query 431 KAFPKDNMLWVEWTTP-RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
D + + W P ++ + KY L++ + +Y L
Sbjct 521 AEAELDTRILLTWLWPVQDPIIKYELQYWEADSD-----NKIHVTFDPAGSYAVEGLKPD 575
Query 490 KCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQ 547
Y ++ G G I+A Q+ PS P V + + W P +
Sbjct 576 TLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQDVHLLSLSSTSIKVSWVAPPAASR 635
Query 548 NGFIRNYTIFYRTIIGNETAVN----VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+G I YT+ Y+ + G +T + + + + L L T Y V + A+TD G G
Sbjct 636 HGAIVRYTVSYQAVNGEDTERHEVPDIGADASSCVLEGLEKWTEYQVWVRAHTDVG--PG 693
Query 604 PEFT 607
PE T
Sbjct 694 PEST 697
Score = 228 bits (580), Expect = 3e-60, Method: Composition-based stats.
Identities = 99/622 (16%), Positives = 211/622 (34%), Gaps = 47/622 (8%)
Query 32 SPESPV-VQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
SP V ++ S T + + + I + ++ P + N S +T
Sbjct 416 SPPLHVQARMLSASTMLVQWEPPEEPNGQIRGYRIYYTSDLDA-PLSAWQKHNTDDSRLT 474
Query 91 FTDIASLNIQLTCNILTFGQLEQ----NVYGITIISGLPPEKPKNLSCIVNEGKKMRCEW 146
+ I + +L F + +V + G+ P +P + ++ W
Sbjct 475 TISSLTTGITYSLRVLGFTSVGDGPPSDVLQVKTQQGV-PAQPSSFEAEAELDTRILLTW 533
Query 147 D-GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
++ + + L+ A P + + A + +G
Sbjct 534 LWPVQDPII--KYELQYWEADSDNK--IHVTFDPAGSYAVEGLKPDTLYKFSLAARSEMG 589
Query 206 K-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP--SIKSVIILKYNIQYR 262
+ V + I PP ++ +++ S+ +K++W P + + I++Y + Y+
Sbjct 590 QGVFTHPIEARTAQSAPSAPPQDVHLLSL--SSTSIKVSWVAPPAASRHGAIVRYTVSYQ 647
Query 263 TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ + D + SS ++ L+ +TEY +R + G G S T
Sbjct 648 AVNGEDTERHEVPDIGADASSCVLEGLEKWTEYQVWVRAHTDVGPGPEST---AVRIRTN 704
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL----- 377
ED P P K++ +++ WK + +G+I Y+V +R ++
Sbjct 705 EDVPGAPP---RKLEVEALNST-AIRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHP 760
Query 378 --------------QNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA 423
+ T + + Y T+ G + +
Sbjct 761 NIMDVALPEAQWKIEESTEYEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTTGAV 820
Query 424 THPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
+ + N ++W P++ V ++ + + + +E +
Sbjct 821 PGKPTMIISTTVGNTALIQWQPPKDMV-GELMGYRLRYKRLEEENYEIREFSRTDDHHTV 879
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQL 542
+L + Y ++ G G + PS P ++ + + L W+
Sbjct 880 TDLHKGATYSFHLSARNRAGLGEEYVKDIGTPEDVPSGFPLNLQVVGLTTSTTRLTWEPP 939
Query 543 PVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ +NG I +Y + YR I + + N +S T+ T+ L DT Y +R+ A+T +GG
Sbjct 940 ALSERNGRIIHYIVVYRDINSKQNSTN-RTSDTQMTIQGLRPDTTYDIRVQAFTSKGGGP 998
Query 603 -GPEFTFTTPKFAQGEIEAIVV 623
P T + + V
Sbjct 999 ISPSIQSRTMSTSPAFATSFGV 1020
Score = 196 bits (498), Expect = 4e-50, Method: Composition-based stats.
Identities = 108/650 (17%), Positives = 205/650 (32%), Gaps = 66/650 (10%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
I P + V + CV Y+ W T + K++ + R +T
Sbjct 237 IPPTNHEVMPGGSVNLTCV-------AVGAPMPYVKWMTGEVELTKDEEMPVGRNVLELT 289
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGG- 149
+ TC ++ + + +++ + P+ P +L+ + WD G
Sbjct 290 ---NIRQSTNYTCVAISSLGMIEATAQVSVKA--LPKPPTSLTVTETTATSVTLTWDSGN 344
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT- 208
E +++ + F + T S + E V A N +G+
Sbjct 345 PEPVSYYIIQYRAKTSDTNFQEVDGVATTRYSI---GGLSPYSEYEFRVMAVNNIGRGPP 401
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST 268
S+ + + +PP L V +S + + W P + I Y I Y T D
Sbjct 402 SEPVETRTGEQAPSSPP--LHVQARMLSASTMLVQWEPPEEPNGQIRGYRI-YYTSDLDA 458
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
+ T+ L Y R+ G G SD T + P++
Sbjct 459 PLSAWQKHNTDDSRLTTISSLTTGITYSLRVLGFTSVGDGPPSDV---LQVKTQQGVPAQ 515
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS----HLQNYTVNA 384
SF + + + L W L P + I+ YE+ S H+ +
Sbjct 516 PSSFEAEAELDTR-----ILLTW--LWPVQD--PIIKYELQYWEADSDNKIHVTFDPAGS 566
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDLKAFP-KDNMLWVE 442
+ + Y +L R+ +G+ + + P D+ + V
Sbjct 567 YAVEGLKPDTLYKFSLAARSEMGQGVFTHPIEARTAQSAPSAPPQDVHLLSLSSTSIKVS 626
Query 443 WTTPRESVK-KYILEWCVLSD---KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
W P + + I+ + V + G + + L + Y + V
Sbjct 627 WVAPPAASRHGAIVRYTVSYQAVNGEDTERHEVPDIGADASSCVLEGLEKWTEYQVWVRA 686
Query 499 VYADGPGSPES-IKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
GPG + ++ + P P + + + + W Q+G IR Y +
Sbjct 687 HTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALNSTAIRVTWKPPLSGKQHGQIRGYQV 746
Query 557 FYRTIIGNETAVNVD---------------SSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
Y + E + + S+ E ++ L S+T Y V +AAYT +G
Sbjct 747 IYSRLENGEPRGHPNIMDVALPEAQWKIEESTEYEAVIAGLASETSYSVTVAAYTTKGDG 806
Query 602 DGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTT-------LLGVLFCFNKR 644
+ T A +++ + ++G L + R
Sbjct 807 ARSKAKVVTTTGAVPGKPTMIISTTVGNTALIQWQPPKDMVGELMGYRLR 856
Score = 178 bits (452), Expect = 2e-44, Method: Composition-based stats.
Identities = 88/527 (17%), Positives = 154/527 (29%), Gaps = 51/527 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGG---RETHLETNFTLKSEWATHKFAD--CKAKRDTP 179
P P+++ + ++ W +T+ + + +
Sbjct 606 PSAPPQDVHLLSLSSTSIKVSWVAPPAASRHGAIVRYTVSYQAVNGEDTERHEVPDIGAD 665
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSS 238
S V + +VWV A +G S + V PP L V S+
Sbjct 666 ASSCVLEGLEKWTEYQVWVRAHTDVGPGPESTAVRIRTNEDVPGAPPRKLEVEALN--ST 723
Query 239 ILKLTWTNP--SIKSVIILKYNIQY-RTKDASTWSQIPPEDT----------ASTRSSFT 285
+++TW P + I Y + Y R ++ D ST
Sbjct 724 AIRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVALPEAQWKIEESTEYEAV 783
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
+ L T Y + G G S T P K T
Sbjct 784 IAGLASETSYSVTVAAYTTKGDGARSK---AKVVTTTGAVPGKP------TMIISTTVGN 834
Query 346 TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY-----TVNATKLTVNLTNDRYLATL 400
T + W+ PP + G+++ Y + R + T + +T Y L
Sbjct 835 TALIQWQ--PPKDMVGELMGYRLRYKRLEEENYEIREFSRTDDHHTVTDLHKGATYSFHL 892
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW-VEWTTPRES-VKKYILEWC 458
+ RN G + V I + + ++L+ + W P S I+ +
Sbjct 893 SARNRAGLGEEYVKDIGTPEDVPSGFPLNLQVVGLTTSTTRLTWEPPALSERNGRIIHYI 952
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQA 517
V+ + T L Y I V + G G SI++
Sbjct 953 VVYRDINSKQNSTNR--TSDTQMTIQGLRPDTTYDIRVQAFTSKGGGPISPSIQSRTMST 1010
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY 577
P+ + K V K +L W+ + + + I Y N+ +V V +
Sbjct 1011 SPAFATSFGVKAVMKTSVLLTWEV--PENYKSQVP-FKILY-----NQQSVEVQGNLKRK 1062
Query 578 TLSSLTSDTLYMVRMAAY-TDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
++ L DT Y + + GG T P + +
Sbjct 1063 LITRLQPDTDYSFVLMSRGNSAGGLQQQVSIRTAPDLFKTKPVLYTA 1109
Score = 138 bits (348), Expect = 6e-32, Method: Composition-based stats.
Identities = 76/570 (13%), Positives = 145/570 (25%), Gaps = 58/570 (10%)
Query 69 TNHFTIPKEQYTIINRTASSVTFTDI---ASLNIQLTCNILTFGQLEQNVYGITIISGLP 125
N + + I ASS + + + + E I +P
Sbjct 649 VNGEDTERHEVPDIGADASSCVLEGLEKWTEYQVWVRAHTDVGPGPESTAVRIRTNEDVP 708
Query 126 PEKPKNLSCIVNEGKKMRCEWDG-------GRETHLETNFTLKSEWATHKFAD----CKA 174
P+ L +R W G+ + ++ +
Sbjct 709 GAPPRKLEVEALNSTAIRVTWKPPLSGKQHGQIRGYQVIYSRLENGEPRGHPNIMDVALP 768
Query 175 KRDTPTSCTVDYSTV-----YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS 229
+ + +Y V + V V A G P P +
Sbjct 769 EAQWKIEESTEYEAVIAGLASETSYSVTVAAYTTKGDGARSKAKVVTTTGAVPGKP---T 825
Query 230 VINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
+I S + + + W P ++ Y ++Y+ + + T TV DL
Sbjct 826 MIISTTVGNTALIQWQPPKDMVGELMGYRLRYKRLEEENYEIREFSRTDD---HHTVTDL 882
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
Y F + G G T ED PS P + + + T +L
Sbjct 883 HKGATYSFHLSARNRAGLGEEY----VKDIGTPEDVPSGFPLNLQVVGLTTS----TTRL 934
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA-TKLTVNLTN--DRYLATLTVRNLV 406
W+ E NG+I+ Y V S + + T++T+ Y +
Sbjct 935 TWEPPALSERNGRIIHYIVVYRDINSKQNSTNRTSDTQMTIQGLRPDTTYDIRVQAFTSK 994
Query 407 GKSD--AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
G ++ + A +KA + + W P +
Sbjct 995 GGGPISPSIQSRTMSTSPAFATSFGVKAV-MKTSVLLTWEVPEN--------YKSQVPFK 1045
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
E + L L Y + G + + P
Sbjct 1046 ILYNQQSVEVQGNLKRKLITRLQPDTDYSFVLMSRGNSAGGLQQQVSIRTAPDLFKTKPV 1105
Query 525 V-RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTL---- 579
+ + + + ++P +R Y I + + ++ E
Sbjct 1106 LYTADQTNNGKLTINLPKVPTSAP---VRCYYIVVVPVSQTSSRQWINPDEMELDELLES 1162
Query 580 ---SSLTSDTLYMVRMAAYTDEGGKDGPEF 606
+ L + + Y PE
Sbjct 1163 SEGAHLRRRRRHTDTVRPYIAAKLSTLPET 1192
>sp|Q90610|NEO1_CHICK Neogenin (Fragment) OS=Gallus gallus OX=9031
PE=2 SV=1
Length=1443
Score = 257 bits (656), Expect = 7e-70, Method: Composition-based stats.
Identities = 115/630 (18%), Positives = 211/630 (33%), Gaps = 63/630 (10%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIIN-RTASSVTF 91
P S N CV Y+ W N + E R S+
Sbjct 221 PSSLTKVTGQNAVFPCV-------AGGFPTPYVRWTKNGEELITEDSERFALRAGGSLLI 273
Query 92 TDIASLNIQ-LTCNILTFGQLEQNVYGITIISGLPPE---KPKNL----------SCIVN 137
+D+ ++ TC + + + +PPE +P N+ C V
Sbjct 274 SDVTEEDVGTYTCIADNENETIEA--QAELAVQVPPEFLKRPANIYAHESMDIVFECEVT 331
Query 138 EGKKMRCEWDGGRETHLETNF----------TLKSEWATHKFADCKAKRDTPTSCTVDYS 187
+W + + +++ L + F C A+ D +
Sbjct 332 GKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQL 391
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP 247
+ +++ + +L T+DH+ P P V+ + + ++LTW P
Sbjct 392 IILDLDVAIPTLPPTSLTSATNDHL---APATTGPLPTAPRDVVATLVSTRFIRLTWRTP 448
Query 248 -SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
S L Y+I Y TK+ ++ + +Q+L P T YVFR+ + G
Sbjct 449 VSDPQGDNLTYSIFY-TKEGINRERVENTSRPG-ETQVMIQNLMPETVYVFRVVAQNKHG 506
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
G S + A+ P AP+ ++ +V + W+T P NG+I +Y
Sbjct 507 HGESSAPLKVAT-QPEVQLPGPAPNIR-----AYAGSPTSVTVTWET--PLSGNGEIQNY 558
Query 367 EVTLTR-WKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGK--SDAAVLTIPACDF 421
++ + Q+ V T+ Y + N G S V+ D
Sbjct 559 KLYYMEKGQDSEQDVDVAGLSYTITGLKKYTEYSFRVVAYNKHGPGVSTQDVVVRTLSDV 618
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPR-ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ P + + W P + I + + K +D + G
Sbjct 619 PSAAPQNLTLEARNSKSIMLHWQPPPAGTHSGQITGYKIRYRKVSRKSDVTESVGGTQLF 678
Query 481 YLRGNLAESKCYLITVTPVYADGPGSP------ESIKAYLKQAPPSKGPTVRTKKVGKNE 534
L L Y + + +G G E+ ++ L ++ + P+ +
Sbjct 679 QLIEGLERGTEYNFRIAAMTVNGTGPATDWVSAETFESDLDESRVPEVPSSLHVRPLVTS 738
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
V+ W P + QN +R Y I Y + + VD YT+ +L + Y++ + A
Sbjct 739 IVVSW--TPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKA 796
Query 595 YTDEG-GKDGPEFTFTTPKFAQGEIEAIVV 623
+ + G G E T P E++ V+
Sbjct 797 FNNVGEGIPLYESAVTRPHSDTSEVDLFVI 826
Score = 180 bits (457), Expect = 4e-45, Method: Composition-based stats.
Identities = 106/538 (20%), Positives = 174/538 (32%), Gaps = 65/538 (12%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P N+ + W+ + E N+ L K D + D
Sbjct 525 PGPAPNIRAYAGSPTSVTVTWETPLSGNGEIQNYKLYY---MEKGQDSEQDVDVAGLSYT 581
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDH-INFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
+ V A N G S + + V P NL++ S + L
Sbjct 582 ITGLKKYTEYSFRVVAYNKHGPGVSTQDVVVRTLSDVPSAAPQNLTLEARNSKS--IMLH 639
Query 244 WTNPSIK--SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
W P S I Y I+YR + E T+ ++ L+ TEY FRI
Sbjct 640 WQPPPAGTHSGQITGYKIRYRKVSRKSDVT---ESVGGTQLFQLIEGLERGTEYNFRIAA 696
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
M +G G +DW + + D S+ P + ++ + W PP N
Sbjct 697 MTVNGTGPATDWVSAETFESDLDE-SRVPEVPSSLHVR--PLVTSIVVSW--TPPENQNI 751
Query 362 KILDYEVTLTRWKSHLQNYTVN--ATKLTVNLTNDR--YLATLTVRNLVGK--------- 408
+ Y + H Q V+ T+ + Y+ TL N VG+
Sbjct 752 VVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAV 811
Query 409 -------SDAAVLTI-----PACDFQATHPVMDLKAFPKD-NMLWVEW---TTPRE---- 448
S+ + I P D P + ++A + + + W + P+
Sbjct 812 TRPHSDTSEVDLFVINAPYTPVPDPSPMMPPVGVQASILSHDTIRITWADNSLPKNQKIT 871
Query 449 SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-P 507
+ Y + W P T ++ + T YL L + Y +V +
Sbjct 872 DARYYTVRWKT---NIPANTKYKTANATTLS-YLVTGLKPNTLYEFSVMVTKGRRSSTWS 927
Query 508 ESIKAYLKQAPPSKGP---TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI--- 561
+ + P+ P TV +K+ ++ W P NG I Y I+Y T
Sbjct 928 MTAHGTTFELVPTSPPKDVTVVSKEGKPRTIIVNWQ--PPSEANGKITGYIIYYSTDVNA 985
Query 562 -IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF-TFTTPKFAQGE 617
I + V + + + LT DT Y ++ A +G E F TPK +
Sbjct 986 EIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKAESSD 1043
Score = 84.5 bits (207), Expect = 3e-15, Method: Composition-based stats.
Identities = 49/242 (20%), Positives = 82/242 (34%), Gaps = 19/242 (8%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETN--------FTLKSEWATHKFADCKAKRDTP 179
P + + +R W + L N +T++ W T+ A+ K K
Sbjct 841 PPVGVQASILSHDTIRITW---ADNSLPKNQKITDARYYTVR--WKTNIPANTKYKTANA 895
Query 180 TSCTVDYSTVY-FVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELS 237
T+ + + + E V T S + V +PP +++V++ E
Sbjct 896 TTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKP 955
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ + W PS + I Y I Y T + E R + +Q+L T Y F
Sbjct 956 RTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYF 1015
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
+I+ G G SE T + S + S +G R V + PP
Sbjct 1016 KIQARNSKGMG---PMSEAVQFRTPKAESSDKMPND-QASGSAGKGSRPVDVGPDYKPPL 1071
Query 358 EA 359
Sbjct 1072 SG 1073
>sp|Q64487|PTPRD_MOUSE Receptor-type tyrosine-protein phosphatase
delta OS=Mus musculus OX=10090 GN=Ptprd PE=1 SV=3
Length=1912
Score = 257 bits (657), Expect = 7e-70, Method: Composition-based stats.
Identities = 91/407 (22%), Positives = 150/407 (37%), Gaps = 38/407 (9%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
K P PP V +E ++ + LTW + + Y IQ++ K++ +
Sbjct 316 QITVKALPKPPGTPVV--TESTATSITLTWDSG--NPEPVSYYIIQHKPKNSEEPYK--- 368
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
E + ++V L P+++Y FR+ + G+G SE T E PS AP
Sbjct 369 EIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRG---PASEPVLTQTSEQAPSSAPRDV- 424
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR-WKSHLQNYTVNA------TKL 387
+ T+ + WK P E NG+I Y V T H+ N+ + T +
Sbjct 425 ---QARMLSSTTILVQWKE--PEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTI 479
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTP 446
+ Y + +G + ++ KA P + + + WT P
Sbjct 480 GNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPP 539
Query 447 RESVK-KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
R Y L + Q+ +Y L + Y ++ G G
Sbjct 540 RSDTIASYELVYRDGDQGEE-----QRITIEPGTSYRLQGLKPNSLYYFRLSARSPQGLG 594
Query 506 SP-ESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
+ I A Q+ PS P + ++ W PV+ QNG I Y++ Y + G
Sbjct 595 ASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDG 654
Query 564 NETAVN----VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
+ + + S T+Y L L T Y + + A+TD G GPE
Sbjct 655 EDFKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVG--PGPES 699
Score = 216 bits (549), Expect = 2e-56, Method: Composition-based stats.
Identities = 107/709 (15%), Positives = 230/709 (32%), Gaps = 73/709 (10%)
Query 23 ELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTII 82
+ + +P ++ S+ T + KE + + + T +
Sbjct 411 QTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTM-DPTQHVNNWMKH 469
Query 83 NRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIIS----GLPPEKPKNLSCIVNE 138
N S +T + +L F + I G+ P +P N
Sbjct 470 NVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGV-PGQPLNFKAEPES 528
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
+ W R + + + + + + T + +
Sbjct 529 ETSILLSWTPPRSDTIASYELVYRDGDQGEEQRITIEPGTSYRLQGLKPNSLY-YFRLSA 587
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP--SIKSVIILK 256
+ LG T++ I+ + PP ++S + S+ + ++W P ++ II +
Sbjct 588 RSPQGLGASTAE-ISARTMQSKPSAPPQDISCTSP--SSTSILVSWQPPPVEKQNGIITE 644
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y+++Y D + S + + ++ L+ +TEY + + G G S
Sbjct 645 YSLKYAAVDGEDFKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESL---S 701
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
T ED PS P K++ V++ W++ P + +G+I Y+V + ++
Sbjct 702 VLIRTDEDVPSGPP---RKVEVEAVNAT-AVKVSWRSPVPNKQHGQIRGYQVHYVKMENG 757
Query 377 LQ-------------------NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
+ T + ++ Y T+T G + +
Sbjct 758 EPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLV 817
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPR---ESVKKYILEWCVLSDKAPCITDWQQED 474
+ + + N ++W P ++ Y L++ + ++ +++
Sbjct 818 STTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKE 877
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK-GPTVRTKKVGKN 533
T + + Y+ ++ G G + + + P+ + ++
Sbjct 878 DHFTATDIH----KGASYVFRLSARNKVGFGEEMVKEISVPEEIPTGFPQNLHSEGTTST 933
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVR 591
L W + +NG I YT+ YR I + + T TL+ L SDT Y V+
Sbjct 934 SVQLSWQPPVLAERNGVITKYTLLYRDINVPLLPMEHLIVPADTSMTLTGLKSDTTYDVK 993
Query 592 MAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKH 650
+ A+T +G P F T ++ A V + LL
Sbjct 994 VRAHTSKGPGPYSPSVQFRTLPVD--QVFAKNFHVKAVMKTSVLLSW------------- 1038
Query 651 IWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEAN 699
+P+ S + P + +++ DG T +V ++
Sbjct 1039 ---EIPENYNSAM----PFKILYDDGKMVEEV--DGRATQKLIVNLKPE 1078
Score = 214 bits (544), Expect = 9e-56, Method: Composition-based stats.
Identities = 101/601 (17%), Positives = 190/601 (32%), Gaps = 61/601 (10%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
I P + + + CV Y+ W + E I R +V
Sbjct 240 IPPTNHEIMPGGSVNITCV-------AVGSPMPYVKWMLGAEDLTPEDDMPIGR---NVL 289
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIIS-GLPPEKPKNLSCIVNEGKKMRCEWDGG 149
+ + TC ++ + + + IT+ + PP P + + WD G
Sbjct 290 ELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPV---VTESTATSITLTWDSG 346
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT- 208
++ + + K T+ + + E V A N +G+
Sbjct 347 NPE--PVSYYIIQHKPKNSEEPYKEIDGIATTRYSVAGLSPYSDYEFRVVAVNNIGRGPA 404
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST 268
S+ + + + P ++ S+ + + W P + I Y + Y T D +
Sbjct 405 SEPVLTQTSEQAPSSAPRDVQARML--SSTTILVQWKEPEEPNGQIQGYRV-YYTMDPTQ 461
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
+ + T+ +L P Y ++ G G S + IT P +
Sbjct 462 HVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSS---DIQVITQTGVPGQ 518
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN----YTVNA 384
+F + + ++ L W I YE+ + +
Sbjct 519 PLNFK-----AEPESETSILLSWTPPRSDT----IASYELVYRDGDQGEEQRITIEPGTS 569
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAAV-LTIPACDFQATHPVMDLK-AFPKDNMLWVE 442
+L N Y L+ R+ G + ++ + + P D+ P + V
Sbjct 570 YRLQGLKPNSLYYFRLSARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVS 629
Query 443 WTTPR-----ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
W P + +Y L++ + + + + YL L + Y ITVT
Sbjct 630 WQPPPVEKQNGIITEYSLKYAAVDGEDFKPHEILGIPSDTTK-YLLEQLEKWTEYRITVT 688
Query 498 PVYADGPGSPE-SIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYT 555
GPG S+ + PS P V + V + W + Q+G IR Y
Sbjct 689 AHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQ 748
Query 556 IFYRTIIGNETAVNV---------------DSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
+ Y + E D++ + +S L +T Y + + AYT +G
Sbjct 749 VHYVKMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGD 808
Query 601 K 601
Sbjct 809 G 809
Score = 188 bits (476), Expect = 3e-47, Method: Composition-based stats.
Identities = 92/596 (15%), Positives = 174/596 (29%), Gaps = 72/596 (12%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRE---THLETNFTLKSEW-ATHKFADCK-AKRD 177
P P+++SC + W + T ++LK F +
Sbjct 607 SKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSLKYAAVDGEDFKPHEILGIP 666
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEEL 236
+ T+ + + + V A +G S + V PP + V
Sbjct 667 SDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTDEDVPSGPPRKVEVEAVN-- 724
Query 237 SSILKLTWTNPSIK--SVIILKYNIQY-RTKDASTWSQIPPEDT----------ASTRSS 283
++ +K++W +P I Y + Y + ++ Q +D +T
Sbjct 725 ATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLADAQWEFDDTTEHD 784
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+ L+P T Y + G G S T P K I+ +
Sbjct 785 MIISGLQPETSYSLTVTAYTTKGDGARSK---PKLVSTTGAVPGKP---RLVINHTQMN- 837
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWK----SHLQNYTVNATKLTVNLTND-RYLA 398
T + W PP + G + Y + R + L+ ++ Y+
Sbjct 838 --TALIQWH--PPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVF 893
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK-DNMLWVEWTTPRESVKKYIL-E 456
L+ RN VG + V I + T +L + + + W P + + ++ +
Sbjct 894 RLSARNKVGFGEEMVKEISVPEEIPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGVITK 953
Query 457 WCVLSDK-APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYL 514
+ +L + + + L Y + V + GPG S++
Sbjct 954 YTLLYRDINVPLLPMEHLIVPADTSMTLTGLKSDTTYDVKVRAHTSKGPGPYSPSVQFRT 1013
Query 515 KQAPPSK--GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS 572
P + K V K +L W+ + N + I Y + VD
Sbjct 1014 --LPVDQVFAKNFHVKAVMKTSVLLSWEI--PENYNS-AMPFKILY---DDGKMVEEVDG 1065
Query 573 SHTEYTLSSLTSDTLYMVRMAAY-TDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLL 631
T+ + +L + Y + GG T P + + I +
Sbjct 1066 RATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMIT 1125
Query 632 TTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGN 687
L P+V P+ +I + P K +
Sbjct 1126 VQL------------------PDV--PANENIKGYYIIIVPLKKSRGKFIKPWESP 1161
Score = 121 bits (304), Expect = 1e-26, Method: Composition-based stats.
Identities = 75/517 (15%), Positives = 136/517 (26%), Gaps = 55/517 (11%)
Query 69 TNHFTIPKEQYTIINRTASSVTFTDI---ASLNIQLTCNILTFGQLEQNVYGITIISGLP 125
+ + I + + I +T + E I +P
Sbjct 652 VDGEDFKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTDEDVP 711
Query 126 PEKPKNLSCIVNEGKKMRCEWDG-------GRETHLETNFTLKSEWATHKFADCKAKRDT 178
P+ + ++ W G+ + ++ K
Sbjct 712 SGPPRKVEVEAVNATAVKVSWRSPVPNKQHGQIRGYQVHYVKMENGEPKGQPMLKDVMLA 771
Query 179 PTSCTVDYSTVYF---------VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS 229
D +T + + + V A G P P
Sbjct 772 DAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRL-- 829
Query 230 VINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
VIN ++++ L + W P + Y +++ KD + + + FT D+
Sbjct 830 VINHTQMNTAL-IQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLE---FSEKEDHFTATDI 885
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
YVFR+ + G G + +E S E+ P+ P + S +VQL
Sbjct 886 HKGASYVFRLSARNKVGFGE--EMVKEISV--PEEIPTGFPQNLH----SEGTTSTSVQL 937
Query 350 VWKTLPPFEANGKILDYEVTLT----RWKSHLQNYTVNATKLTVNLTN--DRYLATLTVR 403
W+ E NG I Y + T +T+ Y +
Sbjct 938 SWQPPVLAERNGVITKYTLLYRDINVPLLPMEHLIVPADTSMTLTGLKSDTTYDVKVRAH 997
Query 404 NLVGKSD-AAVLTIPACDF-QATHPVMDLKAFPKDNMLWVEWTTPRE--SVKKYILEWCV 459
G + + Q +KA + + W P S + + +
Sbjct 998 TSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAV-MKTSVLLSWEIPENYNSAMPFKILY-- 1054
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
+E L NL K Y +T G + A
Sbjct 1055 ------DDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVL 1108
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
P K ++ +P + I+ Y I
Sbjct 1109 RTKPAFIGKTNLDGMITVQLPDVPANEN---IKGYYI 1142
Score = 59.5 bits (142), Expect = 2e-07, Method: Composition-based stats.
Identities = 54/358 (15%), Positives = 106/358 (30%), Gaps = 47/358 (13%)
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ------------ 348
C+ + G S S + + + P P+ + RT
Sbjct 98 CVASNNVGEIS-VSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPE 156
Query 349 LVW----KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRN 404
+ W + NG+I L A ++ + +D+ N
Sbjct 157 ITWFKDFLPVDTSNNNGRIKQ----LRSESIGGTPI-RGALQIEQSEESDQGKYECVATN 211
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR------ESVKKYILEWC 458
G +A + + + V + P N + + S Y+ +W
Sbjct 212 SAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYV-KWM 270
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ ++ D ++ +S Y T V G E+I +A
Sbjct 271 LGAEDLTPEDDM----PIGRNVLELNDVRQSANY----TCVAMSTLGVIEAIAQITVKAL 322
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS-SHTEY 577
P T + L WD + + Y I ++ E +D + T Y
Sbjct 323 PKPPGTPVVTESTATSITLTWDSGNPE----PVSYYIIQHKPKNSEEPYKEIDGIATTRY 378
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT-----TPKFAQGEIEAIVVPVCLAFL 630
+++ L+ + Y R+ A + G E T P A +++A ++ +
Sbjct 379 SVAGLSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTILV 436
>sp|Q90W79|CNTN5_CHICK Contactin-5 OS=Gallus gallus OX=9031 GN=CNTN5
PE=1 SV=1
Length=1027
Score = 253 bits (645), Expect = 2e-69, Method: Composition-based stats.
Identities = 80/421 (19%), Positives = 157/421 (37%), Gaps = 31/421 (7%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP- 273
+ + + P PP VI E + L+W+ + I YN+Q R+ + W +
Sbjct 591 ELLVRGPPGPPG--VVIVEEITDTTATLSWSPGADNHSPISLYNLQARSPFSLGWQTVKT 648
Query 274 -PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF 332
P+ + S +L P+ EY FR+ + G G S S T E P P+
Sbjct 649 VPDVISGDMESAMAVELNPWVEYEFRVVATNKIGTGDPSAPS--RMIRTNEAVPKTPPA- 705
Query 333 WYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQNYTVNATKLTVN 390
+ S G R + + W+ + NG+ Y V + + V ++ +
Sbjct 706 ----NVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSDASKF 761
Query 391 LTND-------RYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLKAFPKD-NMLWV 441
+ D + + V N G + ++ I + + + T +D+KA + + V
Sbjct 762 IYRDESVPPLTPFEVKVGVYNNKGDGPFSPIVVICSAEGEPTAAPIDVKATSLSVSEILV 821
Query 442 EWTTPRESV---KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
W +ES+ + + + + ++ + + L L + Y +TV
Sbjct 822 AWKHIKESLGRPQGFEIGYWKDMEQEEAAEKVK--TAGNESSLLLTGLEGNTLYHLTVRA 879
Query 499 VYADGPGSPES-IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
A G G P + ++ K++PPS+ P+ + L W+ + + Y +
Sbjct 880 YNAAGYGPPSTAVRVATKKSPPSQAPSNVMWIQDGSHVSLGWEPVRPLANESEVMGYKVL 939
Query 558 YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
R + + V + + L +Y++ + A EGG P +A G+
Sbjct 940 LRQEGQSNSQVIETQKTSAVVI--LPDVGVYIIEVCAV-SEGGDGTASPQIRVPSYAGGK 996
Query 618 I 618
+
Sbjct 997 V 997
Score = 128 bits (321), Expect = 8e-29, Method: Composition-based stats.
Identities = 72/506 (14%), Positives = 152/506 (30%), Gaps = 48/506 (9%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTI----PKEQYTIINRTA 86
++P+ + + + C K + ++ + W N I + I A
Sbjct 503 LTPKKIELTVGESIVLSC----KALHDSTLDVTF-YWTLNGQPIDFDKEDGHFESIKAQA 557
Query 87 SS--VTFTDIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
SS + +I ++ + C + T + ++ PP P +
Sbjct 558 SSADLMIRNILLMHAGRYGCRVQTAADAVSDE--TELLVRGPPGPPGVVIVEEITDTTAT 615
Query 144 CEWDGGRETHLETN-FTLKS----EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
W G + H + + L++ + +V E V
Sbjct 616 LSWSPGADNHSPISLYNLQARSPFSLGWQTVKTVPDVISGDMESAMAVELNPWVEYEFRV 675
Query 199 EAENALGKV--TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN--PSIKSVII 254
A N +G ++ V PP N V L + W ++
Sbjct 676 VATNKIGTGDPSAPSRMIRTNEAVPKTPPAN--VSGRSGRRHELVIAWEPVSEEFQNGEG 733
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
Y + +R W + + +++ + + + P T + ++ G G + S
Sbjct 734 FGYIVAFRPNGTRGWKEKMVTSSDASKFIYRDESVPPLTPFEVKVGVYNNKGDGPF---S 790
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQ-GYRTVQLVWKTLPPFEANGKILDYEVTLT-- 371
+ E P+ AP ID T + + WK + E+ G+ +E+
Sbjct 791 PIVVICSAEGEPTAAP-----IDVKATSLSVSEILVAWKHI--KESLGRPQGFEIGYWKD 843
Query 372 ----RWKSHLQNYTVNATKLTVNLT-NDRYLATLTVRNLVGKSDAAV-LTIPACDFQATH 425
++ ++ L L N Y T+ N G + + + +
Sbjct 844 MEQEEAAEKVKTAGNESSLLLTGLEGNTLYHLTVRAYNAAGYGPPSTAVRVATKKSPPSQ 903
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKK-YILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
++ + + + W R + ++ + VL + E +
Sbjct 904 APSNVMWIQDGSHVSLGWEPVRPLANESEVMGYKVLLRQEGQSNSQVIETQKTSAVVI-- 961
Query 485 NLAESKCYLITVTPVYADGPGSPESI 510
L + Y+I V V G G+
Sbjct 962 -LPDVGVYIIEVCAVSEGGDGTASPQ 986
>sp|O88488|PTPRQ_RAT Phosphatidylinositol phosphatase PTPRQ OS=Rattus
norvegicus OX=10116 GN=Ptprq PE=1 SV=1
Length=2302
Score = 254 bits (649), Expect = 8e-69, Method: Composition-based stats.
Identities = 113/609 (19%), Positives = 211/609 (35%), Gaps = 47/609 (8%)
Query 58 FHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQ---- 113
+ N I+ + K IN T +S+ +D+ N+ + +
Sbjct 879 PPLEPNGIILYYTVYVWDKSSLRAINATEASLVLSDLD-YNVDYGACVTASTRFGDGNAR 937
Query 114 -NVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGG-RETHLETNFTLKSEWATHKFAD 171
++ G P + P ++ + + W + + +++ + + F
Sbjct 938 SSIINFRTPEGEPSDPPNDVHYVNLSSSSIILFWTPPVKPNGIIQYYSVYYQNTSGTFVQ 997
Query 172 ------CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV--TSDHINFDPVYKVKPN 223
+ D T Y F W+ A ++G +SD I+ +
Sbjct 998 NFTLLQVTKESDNVTVSARIYRLAIFSYYTFWLTASTSVGNGNKSSDIIHVYTDQDIPEG 1057
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P NL+ + S+ + ++W PS + ++ Y + + + IPP T +S
Sbjct 1058 PVGNLTFESI--SSTAIHVSWEPPSQPNGLVFYY-LSLNLQQSPPRHMIPPLVTY--ENS 1112
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
DL+ +T+Y+F+I E KG+ ++ + T ED P P I+
Sbjct 1113 IDFDDLEKYTDYIFKITPSTE--KGFSETYTTQLHIKTEEDVPDTPP----IINTFKNLS 1166
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLT-RWKSHLQNYTVNATKLTVNLTNDRYLATLTV 402
++ L W PP + NG IL Y +TL +H + N L Y
Sbjct 1167 STSILLSWD--PPLKPNGAILGYHLTLQGPHANHTFVTSGNHIVLEELSPFTLYSFFAAA 1224
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLS 461
R + G +++L + P +L + +W+ W+ + +
Sbjct 1225 RTMKGLGPSSILFFYTDESAPLAPPQNLTLINYTSDFVWLTWSPSPLPGGIVKVYSFKIH 1284
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES--IKAYLKQAPP 519
+ ++ G L G L Y ++V+ G G+ S ++ +++ P
Sbjct 1285 EHETDTVFYKNISGLQTDAKLEG-LEPVSTYSVSVSAFTKVGNGNQYSNVVEFTTQESVP 1343
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTL 579
+ + WD P NG I +Y I T+ GN T V+ YT
Sbjct 1344 EAVRNIECVARDWQSVSVRWD--PPRKTNGIIIHYMI---TVGGNSTKVSPRDP--TYTF 1396
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT-PKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
+ L +T Y+ + A T G + +T P+ P +AF
Sbjct 1397 TKLLPNTSYVFEVRASTSAGEGNESRCDISTLPET------VPSAPTNVAFSNVQSTSAT 1450
Query 639 FCFNKRDLI 647
+ K D I
Sbjct 1451 LTWTKPDTI 1459
Score = 186 bits (472), Expect = 8e-47, Method: Composition-based stats.
Identities = 119/719 (17%), Positives = 227/719 (32%), Gaps = 83/719 (12%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD 177
+ P P+++ ++R +W + N + + ++ AD ++
Sbjct 660 VRTPEDEPESSPQDVQVTGVSPSELRLKWSPPEKP----NGIIIAYEVLYQNADTLFVKN 715
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENAL--GKVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
T T+ + + + + + L G +S ++ V + P N++ N
Sbjct 716 TSTTDIIISDLKPYTLYNISIRSYTRLGHGNQSSSLLSVRTSETVPDSAPENITYKNI-- 773
Query 236 LSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
S +++++ P + II KY I + ++ I T + T+ LK +T Y
Sbjct 774 SSGEIEISFLPPRSPNGIIQKYTIYLKRSNSHEARTINT-----TSLTQTIGGLKKYTHY 828
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
V + G+G S S +T ED P P + S TV L W+ P
Sbjct 829 VIEVSASTLKGEGIRSR---PISILTEEDAPDSPPQNFSVKQLSGV----TVMLSWQ--P 879
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND-RYLATLTVRNLVGKS--DAA 412
P E NG IL Y V + S A+ + +L + Y A +T G ++
Sbjct 880 PLEPNGIILYYTVYVWDKSSLRAINATEASLVLSDLDYNVDYGACVTASTRFGDGNARSS 939
Query 413 VLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPC----- 466
++ + + + P D+ + + + WT P + I + V
Sbjct 940 IINFRTPEGEPSDPPNDVHYVNLSSSSIILFWTPPVKP-NGIIQYYSVYYQNTSGTFVQN 998
Query 467 --ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES--IKAYLKQAPPSKG 522
+ +E V + LA Y +T + G G+ S I Y Q P
Sbjct 999 FTLLQVTKESDNVTVSARIYRLAIFSYYTFWLTASTSVGNGNKSSDIIHVYTDQDIPEGP 1058
Query 523 P-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYT-IFYRTIIGNETAVNVDSSHTEYTLS 580
+ + + + W+ P NG + Y + + + +
Sbjct 1059 VGNLTFESISSTAIHVSWE--PPSQPNGLVFYYLSLNLQQSPPRHMIPPLVTYENSIDFD 1116
Query 581 SLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFC 640
L T Y+ ++ T++G T+TT + E + P + +
Sbjct 1117 DLEKYTDYIFKITPSTEKGF----SETYTTQLHIKTEEDVPDTPPIINTFKNLSSTSILL 1172
Query 641 FNKRDLIKK------HIWPNVPDPSKSHIAQWSPHTPPRHN-------FNSKDQMYSDGN 687
L H+ P + + + + + F + M G
Sbjct 1173 SWDPPLKPNGAILGYHLTLQGPHANHTFVTSGNHIVLEELSPFTLYSFFAAARTMKGLGP 1232
Query 688 FTD----------------------VSVVEIEANDKKPFPEDLKSLDLFKKEKINTEG-- 723
+ S P P + + FK + T+
Sbjct 1233 SSILFFYTDESAPLAPPQNLTLINYTSDFVWLTWSPSPLPGGIVKVYSFKIHEHETDTVF 1292
Query 724 --HSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS 780
+ SG+ + + P + S + + QYS VV + VP
Sbjct 1293 YKNISGLQTDAKLEGLEPVSTYSVSVSAFTKVGNGNQYSNVVEFTTQESVPEAVRNIEC 1351
Score = 182 bits (462), Expect = 1e-45, Method: Composition-based stats.
Identities = 116/669 (17%), Positives = 212/669 (32%), Gaps = 61/669 (9%)
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN-SEELSSILKLTWTNPSI 249
F + V A +G+ + +V P ++ +IN SS + L W P
Sbjct 541 FTEHTISVSAFTIMGEGPPTVLTVRTREQV----PSSIQIINYKNISSSSILLYWDPPEY 596
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ I Y I A+ + +SF + LK +T Y R+ G+
Sbjct 597 PNGKITHYTI-----YATELDTNRAFQMTTVDNSFLITGLKKYTRYKMRVAASTHVGESS 651
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
S+ + T ED P +P S ++L W PP + NG I+ YEV
Sbjct 652 LSE-ENDIFVRTPEDEPESSPQDVQVTGVS----PSELRLKWS--PPEKPNGIIIAYEVL 704
Query 370 LTRWKSHLQNYTVNATKLTVNL-TNDRYLATLTVRNLVGKS--DAAVLTIPACDFQATHP 426
+ T + +L Y ++ +G +++L++ +
Sbjct 705 YQNADTLFVKNTSTTDIIISDLKPYTLYNISIRSYTRLGHGNQSSSLLSVRTSETVPDSA 764
Query 427 VMDLKAFPKDN-MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
++ + + + + PR S I ++ + + + T T G
Sbjct 765 PENITYKNISSGEIEISFLPPR-SPNGIIQKYTIYL--KRSNSHEARTINTTSLTQTIGG 821
Query 486 LAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLP 543
L + Y+I V+ G G I ++ P P K++ +L W P
Sbjct 822 LKKYTHYVIEVSASTLKGEGIRSRPISILTEEDAPDSPPQNFSVKQLSGVTVMLSWQ--P 879
Query 544 VDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD- 602
NG I YT++ + + ++++ LS L + Y + A T G +
Sbjct 880 PLEPNGIILYYTVY---VWDKSSLRAINATEASLVLSDLDYNVDYGACVTASTRFGDGNA 936
Query 603 -GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKS 661
F TP+ + P + + F + I ++
Sbjct 937 RSSIINFRTPEGEPSD------PPNDVHYVNLSSSSIILFWTPPVKPNGIIQYYSVYYQN 990
Query 662 HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINT 721
+ NF N T + + A S + K +
Sbjct 991 TSGTFV------QNFTLLQVTKESDNVTVSARIYRLAIFSYYTFWLTASTSVGNGNKSSD 1044
Query 722 EGHSSG---IGGSSCMSSSRPSISSSDEN---ESSQNTSSTVQYS---TVVHSGYRHQVP 772
H I + + SISS+ + E + V Y + S RH +P
Sbjct 1045 IIHVYTDQDIPEGPVGNLTFESISSTAIHVSWEPPSQPNGLVFYYLSLNLQQSPPRHMIP 1104
Query 773 SVQVFSRSESTQPLLDSEERPED--LQLVDHVDGG-DGILPRQQYFKQNCSQHESSPDIS 829
+ + S D E+ D ++ + G Q + K ++ P I+
Sbjct 1105 PLVTYENSID----FDDLEKYTDYIFKITPSTEKGFSETYTTQLHIKTEEDVPDTPPIIN 1160
Query 830 HFERSKQVS 838
F+ S
Sbjct 1161 TFKNLSSTS 1169
Score = 170 bits (429), Expect = 1e-41, Method: Composition-based stats.
Identities = 80/518 (15%), Positives = 154/518 (30%), Gaps = 47/518 (9%)
Query 109 GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHK 168
G ++ + +P NL+ + W+ + + + L
Sbjct 1039 GNKSSDIIHVYTDQDIPEGPVGNLTFESISSTAIHVSWEPPSQPNGLVFYYLSLNLQQSP 1098
Query 169 FADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN--ALGKVTSDHINFDPVYKVKPNPPH 226
T + + + + + + ++ V PP
Sbjct 1099 PRHMIPPLVTYENSIDFDDLEKYTDYIFKITPSTEKGFSETYTTQLHIKTEEDVPDTPPI 1158
Query 227 NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 286
+ N S+ + L+W P + IL Y++ + A+ ++ + +
Sbjct 1159 INTFKNL--SSTSILLSWDPPLKPNGAILGYHLTLQGPHANH-------TFVTSGNHIVL 1209
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
++L PFT Y F G G S T E P P I+ +
Sbjct 1210 EELSPFTLYSFFAAARTMKGLG----PSSILFFYTDESAPLAPPQNLTLINYTSDF---- 1261
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKS---HLQNYTVNATKLTVNLTNDRYLATLTVR 403
V L W P K+ +++ + + KL Y +++
Sbjct 1262 VWLTWSPSPLPGGIVKVYSFKIHEHETDTVFYKNISGLQTDAKLEGLEPVSTYSVSVSAF 1321
Query 404 NLVGKSDAAVLTI-PACDFQATHPVMDLKAFPKD-NMLWVEWTTPRESVKKYILEWCVLS 461
VG + + V +++ +D + V W PR+ I+ + +
Sbjct 1322 TKVGNGNQYSNVVEFTTQESVPEAVRNIECVARDWQSVSVRWDPPRK-TNGIIIHYMITV 1380
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPS 520
+ TY L + Y+ V + G G+ + L + PS
Sbjct 1381 GGNS-----TKVSP-RDPTYTFTKLLPNTSYVFEVRASTSAGEGNESRCDISTLPETVPS 1434
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-------------ETA 567
V V A L W D G+ +NY I + +
Sbjct 1435 APTNVAFSNVQSTSATLTW--TKPDTIFGYFQNYKITTQLRAQKCREWEPEECIEHQKDQ 1492
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+++ TE T+ L Y ++AA T+ G + E
Sbjct 1493 YLYEANQTEETVHGLKKFRWYRFQVAASTNVGYSNASE 1530
Score = 151 bits (380), Expect = 1e-35, Method: Composition-based stats.
Identities = 96/567 (17%), Positives = 174/567 (31%), Gaps = 81/567 (14%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P P+NL+ I + W L + K + + + +
Sbjct 1245 PLAPPQNLTLINYTSDFVWLTWSPSP---LPGGIVKVYSF---KIHEHETDTVFYKNISG 1298
Query 185 DYSTVYF------VNIEVWVEAENALGKVT--SDHINFDPVYKVKPNPPHNLSVINSEEL 236
+ V V A +G S+ + F V P N+ + +
Sbjct 1299 LQTDAKLEGLEPVSTYSVSVSAFTKVGNGNQYSNVVEFTTQESV-PEAVRNIECVARDWQ 1357
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
S + + W P + II+ Y I +++ P D ++T L P T YV
Sbjct 1358 S--VSVRWDPPRKTNGIIIHYMITV----GGNSTKVSPRD-----PTYTFTKLLPNTSYV 1406
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
F +R G+G S T + AP+ + T + L W P
Sbjct 1407 FEVRASTSAGEGNESR----CDISTLPETVPSAPTNVAFSNVQST----SATLTW--TKP 1456
Query 357 FEANGKILDYEVT-------LTRWK-----SHLQN---YTVNATKLTVNLTNDR--YLAT 399
G +Y++T W+ H ++ Y N T+ TV+ Y
Sbjct 1457 DTIFGYFQNYKITTQLRAQKCREWEPEECIEHQKDQYLYEANQTEETVHGLKKFRWYRFQ 1516
Query 400 LTVRNLVGKS-DAAVLTIPACDFQATHPVMDLKAFPKDN-MLWVEWTTPRESVKK--YIL 455
+ VG S + ++ P ++ + + W+ P Y++
Sbjct 1517 VAASTNVGYSNASEWISTQTLPGPPDGPPENVHVVATSPFGINISWSEPAVITGPTFYLI 1576
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA-------DGPGSPE 508
+ + D I+ + + NL Y + +T DG S
Sbjct 1577 DVKSVDDDDFNISFLKSNEENKTTEI--NNLEVFTRYSVVITAFVGNVSRAYTDGK-SSA 1633
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAV-LEWDQLPVDVQNGFIRNY-TIFYRTIIGNET 566
+ ++ P P T + +E + LP NG IR Y + YR
Sbjct 1634 EVIITTLESVPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIRVYQALVYREDDPTAV 1693
Query 567 AVN----VDSSHTEYT--LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
++ + + T L L Y + + A G + T A ++
Sbjct 1694 QIHNFSIIQKTDTSIIAMLEGLKGGHTYNISVYAINSAGAGPKVQMRITMDIKAPARPKS 1753
Query 621 IVVPV---CLAFLLTTLLGVLF---CF 641
+P+ L+T+ + C+
Sbjct 1754 KPIPIRDATGKLLVTSTTITIRMPICY 1780
Score = 149 bits (376), Expect = 3e-35, Method: Composition-based stats.
Identities = 88/508 (17%), Positives = 161/508 (32%), Gaps = 55/508 (11%)
Query 112 EQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG--GRETHLETNFTLKSEWATHKF 169
+ ++ I+SG PE C N + W T T+++ ++
Sbjct 205 DVSLRVEDILSGKLPE------CNENSESFL---WSTTSPSPTLGRVTPTVRTTQSSSTA 255
Query 170 ADCKAKRDTPTSCTVDYSTVY-FVNIEVWVEA-ENALGKVTSDHINFDPVYKVKPNPPHN 227
A K + + + + V A G + S V PP N
Sbjct 256 ARSKISSVWKEPISFVVTHLRPYTTYLFEVSAVTTEAGYIDST--IVRTPESVPEGPPQN 313
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
I ++W P+I + Y ++ D ++ F
Sbjct 314 C--IMGNVTGKAFSISWDPPTIVTGKF-SYRVELYGPSGR------ILDNSTKDLRFAFT 364
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV 347
L PFT Y + G G S+ S T D P +
Sbjct 365 HLTPFTMYDVYVAAETSAGVGPKSN----LSVFTPPDVPGAVFDL-----QIAEVEATEI 415
Query 348 QLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG 407
++ W+ P + NG I Y V ++ ++ + + T LT + + + NLV
Sbjct 416 RITWRK--PRQPNGIISQYRVKVSVLETGV---VLENTLLTGQDESISNPMSPEIMNLV- 469
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
++ + + + +F ++ P S
Sbjct 470 ---DPMIGFYEGSGEMSSDLHSPASFIYNS-------HPHNDFPASTRAEEQSSPVVTTR 519
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
+ + +Y+ L + I+V+ G G P + ++ PS +
Sbjct 520 NQYMTDITAEQLSYVVRRLVPFTEHTISVSAFTIMGEGPPTVLTVRTREQVPSSIQIINY 579
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTL 587
K + + +L WD P + NG I +YTI+ + N A + + + ++ L T
Sbjct 580 KNISSSSILLYWD--PPEYPNGKITHYTIYATELDTN-RAFQMTTVDNSFLITGLKKYTR 636
Query 588 YMVRMAAYTDEGGKDGPEFT---FTTPK 612
Y +R+AA T G E TP+
Sbjct 637 YKMRVAASTHVGESSLSEENDIFVRTPE 664
Score = 129 bits (325), Expect = 4e-29, Method: Composition-based stats.
Identities = 63/426 (15%), Positives = 116/426 (27%), Gaps = 81/426 (19%)
Query 192 VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS 251
++ + + + +S KP PP L+ + L+W P +
Sbjct 29 TGYDITLSSV-SATTYSSPVSRTLATNVTKPGPPVFLAGERVGSAG--ILLSWNTPPNPN 85
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
I+ Y ++Y+ + + +L P T Y ++ G G +S
Sbjct 86 GRIISYVVKYKEVCPWMQTAYTRARAKPDSLEVLLTNLNPGTTYEIKVAAENNAGIGVFS 145
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
D T E P K + + Y V L+W P + NGKI +++++
Sbjct 146 DPF---LFQTAESAPGKVVNLTVEA-----LNYSAVNLIW--YLPRQPNGKITSFKISVK 195
Query 372 RWKSHLQNYTV---------------NATKLTVNLTNDRYLATL-----TVRNLVGKSDA 411
+S + V N + + TL TVR S A
Sbjct 196 HARSGIVVKDVSLRVEDILSGKLPECNENSESFLWSTTSPSPTLGRVTPTVRTTQSSSTA 255
Query 412 AVLTIPAC-----------------------------------------DFQATHPVMDL 430
A I + P +
Sbjct 256 ARSKISSVWKEPISFVVTHLRPYTTYLFEVSAVTTEAGYIDSTIVRTPESVPEGPPQNCI 315
Query 431 KAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
+ W P K+ + + ++ T + +L
Sbjct 316 MGNVTGKAFSISWDPPTIVTGKFSYRVELYGPSGRIL-----DNSTKDLRFAFTHLTPFT 370
Query 491 CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
Y + V + G G ++ + P ++ +V E + W NG
Sbjct 371 MYDVYVAAETSAGVGPKSNLSVFTPPDVPGAVFDLQIAEVEATEIRITWR--KPRQPNGI 428
Query 551 IRNYTI 556
I Y +
Sbjct 429 ISQYRV 434
Score = 74.9 bits (182), Expect = 3e-12, Method: Composition-based stats.
Identities = 37/238 (16%), Positives = 66/238 (28%), Gaps = 28/238 (12%)
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR---ES 449
Y TL+ + S T+ + PV + + W TP
Sbjct 28 GTGYDITLSSVSATTYSSPVSRTLATNVTKPGPPVFLAGERVGSAGILLSWNTPPNPNGR 87
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTY------LRGNLAESKCYLITVTPVYADG 503
+ Y++++ + W Q T R L NL Y I V G
Sbjct 88 IISYVVKYKE-------VCPWMQTAYTRARAKPDSLEVLLTNLNPGTTYEIKVAAENNAG 140
Query 504 PGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII 562
G + ++ P K + + + + L W NG I ++ I +
Sbjct 141 IGVFSDPFLFQTAESAPGKVVNLTVEALNYSAVNLIW--YLPRQPNGKITSFKISVKHAR 198
Query 563 GNETAVNVDSSHTEYTLSSLT---SDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
+V + L ++ + + T P TP +
Sbjct 199 SGIVVKDVSLRVEDILSGKLPECNENSESFLW--STTS----PSPTLGRVTPTVRTTQ 250
Score = 69.1 bits (167), Expect = 2e-10, Method: Composition-based stats.
Identities = 44/266 (17%), Positives = 84/266 (32%), Gaps = 24/266 (9%)
Query 125 PPE-KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEW-ATHKFADCKAKRDTPTSC 182
PP+ P+N+ + + W T + + + F K +
Sbjct 1540 PPDGPPENVHVVATSPFGINISWSEPAVITGPTFYLIDVKSVDDDDFNISFLKSNEENKT 1599
Query 183 TVDYSTVYFVNIEVWVEAENALGKV--------TSDHINFDPVYKVKPNPPHNLSVINSE 234
T + F V + A +G V +S + + V +PP+N++
Sbjct 1600 TEINNLEVFTRYSVVITAF--VGNVSRAYTDGKSSAEVIITTLESVPKDPPNNMTFQKIP 1657
Query 235 ELSSILKLTWTNPSIKSVIILKYN-IQYRTKDASTWSQIPPEDTASTRSS--FTVQDLKP 291
+ + +LT+ PS + I Y + YR D + T +S ++ LK
Sbjct 1658 DEVTKFQLTFLPPSQPNGNIRVYQALVYREDDPTAVQIHNFSIIQKTDTSIIAMLEGLKG 1717
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYE----DRPSKAPSFWYKIDPSHTQGYRTV 347
Y + + G G + IT + RP P T+
Sbjct 1718 GHTYNISVYAINSAGAGP-----KVQMRITMDIKAPARPKSKPIPIRDATGKLLVTSTTI 1772
Query 348 QLVWKTLPPFEANGKILDYEVTLTRW 373
+ + +G I + +V +
Sbjct 1773 TIRMPICYYNDDHGPIRNVQVLVAET 1798
>sp|P97798|NEO1_MOUSE Neogenin OS=Mus musculus OX=10090 GN=Neo1
PE=1 SV=2
Length=1492
Score = 252 bits (644), Expect = 2e-68, Method: Composition-based stats.
Identities = 113/634 (18%), Positives = 215/634 (34%), Gaps = 70/634 (11%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQY-TIINRTASSVTF 91
P S + + CV+ + A + W N + E ++ +
Sbjct 266 PSSMMKVTGQSAVLPCVV-------SGLPAPVVRWMKNEEVLDTESSGRLVLLAGGCLEI 318
Query 92 TDIASLNIQ-LTCNILTFGQLEQNVYGITIISGLPPE---KPKNL----------SCIVN 137
+D+ + C + + + +PP +P N+ C V
Sbjct 319 SDVTEDDAGTYFCIADNGNKTVEA--QAELTVQVPPGFLKQPANIYAHESMDIVFECEVT 376
Query 138 EGKKMRCEWDGGRETHLETNF----------TLKSEWATHKFADCKAKRDTPTSCTVDYS 187
+W + + +++ L + F C A+ D +
Sbjct 377 GKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQL 436
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP 247
+ ++ + +L T+DH+ P P V+ S + +KLTW P
Sbjct 437 IILEHDVAIPTLPPTSLTSATTDHL---APATTGPLPSAPRDVVASLVSTRFIKLTWRTP 493
Query 248 -SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
S L Y++ Y TK+ ++ T+Q+L P T Y+F++ + G
Sbjct 494 ASDPHGDNLTYSVFY-TKEGVARERVENTSQPG-EMQVTIQNLMPATVYIFKVMAQNKHG 551
Query 307 KGYWSDWSEEASGITYEDR--PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
G + S T + P AP+ ++ ++ + W+T P NG+I
Sbjct 552 SG---ESSAPLRVETQPEVQLPGPAPNIR-----AYATSPTSITVTWET--PLSGNGEIQ 601
Query 365 DYEVTLTRWKS-HLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGK--SDAAVLTIPAC 419
+Y++ + Q+ V++ T+N Y + N G S V
Sbjct 602 NYKLYYMEKGTDKEQDIDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLS 661
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVK-KYILEWCVLSDKAPCITDWQQ--EDGT 476
D + P + + W P + + I + + KA +D + GT
Sbjct 662 DVPSAAPQNLSLEVRNSKSIVIHWQPPSSTTQNGQITGYKIRYRKASRKSDVTETLVTGT 721
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSP------ESIKAYLKQAPPSKGPTVRTKKV 530
+ G L Y V + +G G E+ ++ L + + P+ +
Sbjct 722 QLSQLIEG-LDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRP 780
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMV 590
V+ W P + QN +R Y I Y + + VD YT+ +L + Y++
Sbjct 781 LVTSIVVSW--TPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVI 838
Query 591 RMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVV 623
+ A+ + G G E T P E++ V+
Sbjct 839 TLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVI 872
Score = 183 bits (465), Expect = 4e-46, Method: Composition-based stats.
Identities = 122/643 (19%), Positives = 199/643 (31%), Gaps = 84/643 (13%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P V L S + D N Y V+ T + VT
Sbjct 473 PRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGVARERVENTSQPGEMQVTIQ 532
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLP-----------PEKPKNLSCIVNEGKK 141
++ + + F + QN +G S P P N+
Sbjct 533 NL------MPATVYIFKVMAQNKHGSG-ESSAPLRVETQPEVQLPGPAPNIRAYATSPTS 585
Query 142 MRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
+ W+ + E N+ L K D + D + + V A
Sbjct 586 ITVTWETPLSGNGEIQNYKLYY---MEKGTDKEQDIDVSSHSYTINGLKKYTEYSFRVVA 642
Query 201 ENALGKVTSDH-INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK--SVIILKY 257
N G S + + V P NLS+ S + + W PS + I Y
Sbjct 643 YNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKS--IVIHWQPPSSTTQNGQITGY 700
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW-SEE 316
I+YR S + T+ S ++ L TEY FR+ + +G G +DW S E
Sbjct 701 KIRYRKASRK--SDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAE 758
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
++ + P T ++ + W PP N + Y + H
Sbjct 759 TFESDLDETRVPEVPSSLHVRPLVT----SIVVSW--TPPENQNIVVRGYAIGYGIGSPH 812
Query 377 LQNYTVN--ATKLTVNLTNDR--YLATLTVRNLVGK----------------SDAAVLTI 416
Q V+ T+ + Y+ TL N VG+ S+ + I
Sbjct 813 AQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVI 872
Query 417 -----PACDFQATHPVMDLKAFPKD-NMLWVEWTTPRE-------SVKKYILEWCVLSDK 463
P D P + ++A + + + W + Y + W
Sbjct 873 NAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKT---N 929
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKG 522
P T ++ + T YL L + Y +V + + + P+
Sbjct 930 IPANTKYKNANATTLS-YLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSP 988
Query 523 P---TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI----IGNETAVNVDSSHT 575
P TV +K+ ++ W P NG I Y I+Y T I + V +
Sbjct 989 PKDVTVVSKEGKPRTIIVNWQ--PPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRL 1046
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF-TFTTPKFAQGE 617
+ + LT DT Y ++ A +G E F TPK +
Sbjct 1047 THQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSD 1089
>sp|A2ABU4|MYOM3_MOUSE Myomesin-3 OS=Mus musculus OX=10090 GN=Myom3
PE=1 SV=1
Length=1439
Score = 252 bits (642), Expect = 4e-68, Method: Composition-based stats.
Identities = 141/750 (19%), Positives = 241/750 (32%), Gaps = 92/750 (12%)
Query 43 NFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIP---KEQYTIINRTASSVTFTDIASLNI 99
F+ C+ + ++ I W + + + Q +R AS
Sbjct 287 PFSLTCLFSDDVLEA----EQRIQWYRDGRLLRSSTRRQILYADRQASVKVSCAYKEDEG 342
Query 100 QLTCNIL-TFGQLEQNVYG--ITIISGLP--PEKPKNLSCIVNEGKKMRCEWDGGRET-- 152
T + FG EQ+ Y + P P P N+ C+ + W +T
Sbjct 343 FYTIRVSSPFGPQEQSAYVFIRDAAAEKPGAPGSPLNVRCLNVHRDCLTLTWVPPSDTRG 402
Query 153 HLETNFTLK-SEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV---- 207
T ++++ + + ++ C C + + + V A + G
Sbjct 403 STITGYSIEMCQGDSEEWMPCLKAPGGTCRCPIQGLVEG-QSYQFRVRAISKAGTSLPSK 461
Query 208 --------------TSDHINFDP------------VYKVKPNPPHNLSVINSEELSSILK 241
S I +D P+ P N V SE +
Sbjct 462 ASEAVVTGDYDAVHKSTEIPYDLGSKITISKNDFEDAVTIPSAPTN--VHASEIREAYAV 519
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
L+W P + L Y ++ + TW I E T F + DL+ YVFR+R
Sbjct 520 LSWEEPRPRGRAPLTYTLEKSVIGSGTWEAISTE-TPIKSPRFALLDLEKGKSYVFRVRA 578
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ + G S+ SE + + +P+ P +TQ +V L W+ + +
Sbjct 579 LNQYGMSDPSEPSEPVA---LKGKPATLPPPAQVQAFRNTQ--TSVSLAWEPV---DGGS 630
Query 362 KILDYEVTLTR----WKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAAVLT 415
++L Y + + N + TK TV T Y + + G +++ T
Sbjct 631 ELLGYYIYSREAGASEWQTVNNKPIQDTKFTVPGLRTGKEYDFCIRSVSEAGVGESSAAT 690
Query 416 IPACDFQATHPVMDLKAFP----KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
P QA F N + + W P+ IL + + +DW
Sbjct 691 QPVRVKQALATPSAPYDFALLNCGKNEMVIGWKPPKRRGGGKILGYF-MDQHDSVESDWH 749
Query 472 --QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG---SPESIKAYLKQAPPSKGPT-- 524
R NL E Y V G G +P S+ + P GP
Sbjct 750 PVNRQPIPSRVCKVTNLHEGHFYEFRARAVNWAGIGELSAPSSLFECKEWTMPEPGPPYD 809
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD--SSHTEYTLSSL 582
VR +V +L+W+ P+ + G + Y + ++ E +S T +S L
Sbjct 810 VRVSEVQATSVMLQWEP-PLYIGAGPVTGYHVSFQEKGSEEWKPVTPDATSDTHLRVSDL 868
Query 583 TSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL----AFLLTTLLGVL 638
YM R+ A G P T P + + +A + V + L
Sbjct 869 QPGKQYMFRVQAMNSAGLGQ-PSVP-TDPVLLEDKPDAQEIEVGVDDEGQIYLAFEAPEA 926
Query 639 FCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEA 698
F + K + P PDP Q + + SVV +A
Sbjct 927 PDFPEFQWSKDYQGP--PDP------QRVEVEDEISKSKVILKEPDLQDLGIYSVVVPDA 978
Query 699 NDKKPFPEDLKSLDLFKKEKINTEGHSSGI 728
++ L +L K +K++ E + I
Sbjct 979 DEDTSASHTLTEEELNKLKKLSHEIRNPVI 1008
>sp|Q8K4B4|IL23R_MOUSE Interleukin-23 receptor OS=Mus musculus
OX=10090 GN=Il23r PE=2 SV=1
Length=644
Score = 241 bits (615), Expect = 1e-67, Method: Composition-based stats.
Identities = 78/331 (24%), Positives = 137/331 (41%), Gaps = 24/331 (7%)
Query 2 LTLQTWLVQALFIFLTTESTGELLDPCG---YISPESPVVQLHSNFTAVCVLKEKCMDYF 58
LTLQ +V AL++ G C ++ P + Q+ N + C K
Sbjct 4 LTLQLHVVIALYVLFRWCHGGITSINCSGDMWVEP-GEIFQMGMNVSIYCQEALK----- 57
Query 59 HVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQN-VYG 117
H + + N F + T INRT + + + + + + C G ++ + G
Sbjct 58 HCRPRNLYFYKNGFK-EEFDITRINRTTARIWYKGFSEPHAYMHCTAECPGHFQETLICG 116
Query 118 ITIISGLPPEKPKNLSCIVNE-GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKR 176
I SG PP+ P NL+C++ E M C W+ G+ T+++T + + K + + ++
Sbjct 117 KDISSGHPPDAPSNLTCVIYEYSGNMTCTWNTGKPTYIDTKYIVHV-----KSLETEEEQ 171
Query 177 DTPTSCTVDYSTVYFVN---IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS 233
S V ST VWV+A N+LG S ++ V P+ +
Sbjct 172 QYLASSYVKISTDSLQGSRKYLVWVQAVNSLGMENSQQLHVHLDDIVIPSASIISRAETT 231
Query 234 EELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
+ + W + ++ + ++Y+T TWS + D T + L+P +
Sbjct 232 NDTVPKTIVYWKSKTMIEKVF--CEMRYKTTTNQTWS-VKEFDANFTYVQQSEFYLEPDS 288
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
+YVF++RC E GK W WS T ++
Sbjct 289 KYVFQVRCQ-ETGKRNWQPWSSPFVHQTSQE 318
Score = 48.3 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 72/485 (15%), Positives = 153/485 (32%), Gaps = 107/485 (22%)
Query 326 PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT 385
P APS + ++ + W T P + Y V + ++ + + ++
Sbjct 124 PPDAPSNLTCVIYEYSG---NMTCTWNTGKPTYID---TKYIVHVKSLETEEEQQYLASS 177
Query 386 KLTVNLTNDR----YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNML-- 439
+ ++ + + YL + N +G ++ L + D + +A ++ +
Sbjct 178 YVKISTDSLQGSRKYLVWVQAVNSLGMENSQQLHVHLDDIVIPSASIISRAETTNDTVPK 237
Query 440 -WVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN---LAESKCYLIT 495
V W +++ + + C + K W ++ + TY++ + L Y+
Sbjct 238 TIVYWK--SKTMIEKVF--CEMRYKTTTNQTWSVKEFDANFTYVQQSEFYLEPDSKYVFQ 293
Query 496 VTPVYADG-----PGSPESIKAYLKQA-----PPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
V G P S + ++ P P V ++ + P
Sbjct 294 VR-CQETGKRNWQPWSSPFVHQTSQETGKRNWQPWSSPFVHQTSQTVSQVTAKSSHEP-- 350
Query 546 VQNGFIRNYTIFYR-TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
Q + + TIF GN + L S ++
Sbjct 351 -QKMEMLSATIFRGHPASGNHQDI------------GLLSGMVF---------------- 381
Query 605 EFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIA 664
P F+ L + L + +I K ++ ++P+ S++A
Sbjct 382 -LAIMLPIFS------------LIGIFNRSLRIGIKRKVLLMIPKWLYEDIPNMENSNVA 428
Query 665 QWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGH 724
+ N N+ +Q + EI + KP +K+E++
Sbjct 429 KLLQEKSVFENDNASEQALYVDPVL-TEISEISPLEHKPT--------DYKEERLTGL-- 477
Query 725 SSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQV----PSVQVFSRS 780
+ + D +TSS+V Y +++GY+ QV P +F
Sbjct 478 ----------------LETRDCPLGMLSTSSSVVYIPDLNTGYKPQVSNVPPGGNLFINR 521
Query 781 ESTQP 785
+ P
Sbjct 522 DERDP 526
>sp|Q8WZ42|TITIN_HUMAN Titin OS=Homo sapiens OX=9606 GN=TTN PE=1
SV=4
Length=34350
Score = 250 bits (637), Expect = 4e-67, Method: Composition-based stats.
Identities = 124/595 (21%), Positives = 197/595 (33%), Gaps = 54/595 (9%)
Query 62 ANYIVWK---TNHFTIPKEQYTIINRTASSVTFT------DIASLNIQ--LTCNILTFGQ 110
+W N P Y I R S + + + S + N F
Sbjct 28994 EKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRV 29053
Query 111 LEQNVYGITIISGL----------PPEKPKNLSCIVNEGKKMRCEW-DGGRETH--LETN 157
N +G+ P+ P G + W + ++
Sbjct 29054 SAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQY 29113
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPV 217
+ E + ++ +KR + E V AENA G + I+
Sbjct 29114 ILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIK 29173
Query 218 YKVKPNPPHNLSVINSEELS-SILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPE 275
+ NPP +V+ + S + + L W+ P + I+ Y I+ D W ++ E
Sbjct 29174 CREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAE 29233
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
++ +TV DL+ EY FR+ + GKG S E +G AP
Sbjct 29234 ACV--KTRYTVTDLQAGEEYKFRVSAINGAGKGD----SCEVTGTIKAVDRLTAPELDID 29287
Query 336 IDPSHTQGYRT-----VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN 390
+ T R + + ++ P A D ++L H + T N
Sbjct 29288 ANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRA-DIHTTDSFSTLTVENCN 29346
Query 391 LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV 450
ND TLTV N G S + T+ D + K + + + W P
Sbjct 29347 -RNDAGKYTLTVENNSG-SKSITFTVKVLDTPGPPGPITFKDVTRGSATLM-WDAPLLDG 29403
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN-LAESKCYLITVTPVYADGPG---- 505
I + V+ + WQ R + N LAE Y V+ V G G
Sbjct 29404 GARIHHY-VVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYE 29462
Query 506 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG-FIRNYTIFYRTIIGN 564
PE I A + APP + + K+ AVL W L D G I Y + R +
Sbjct 29463 MPEPIVATEQPAPPRR---LDVVDTSKSSAVLAW--LKPDHDGGSRITGYLLEMRQKGSD 29517
Query 565 ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE 619
+ +T+ L T Y R+ A D G + P F++ + +IE
Sbjct 29518 FWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIE 29571
Score = 211 bits (537), Expect = 1e-54, Method: Composition-based stats.
Identities = 130/617 (21%), Positives = 205/617 (33%), Gaps = 44/617 (7%)
Query 13 FIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHF 72
+I + G P + P V EKC ++ +H+
Sbjct 25706 YILKLSNVGGTKSIPITVKVLDRPGPPEG-PLKVTGVTAEKCYLAWNPPLQDGGANISHY 25764
Query 73 TIPKEQYTIINRTASSVTFTDIASLNIQLT----CNILTFGQLEQNVYGI--TIISG--- 123
I K + + ++ T S T++ +LN ++T N F + N YGI + SG
Sbjct 25765 IIEKRETSRLSWTQVS---TEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT 25821
Query 124 -----LPPEKPKNLSCIVNEGKKMRCEWDGGRE---THLETNFTLKSEWATHKFADCKAK 175
PP P M W + T +E K + ++ C K
Sbjct 25822 ACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKK 25881
Query 176 RDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-TSDHINFDPVYKV--KPNPPHNLSVIN 232
T V T + E V AENA G S+ F P PP N V +
Sbjct 25882 TLTDLRLRVTGLTEGH-SYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTD 25940
Query 233 SEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ S + L W+ P + Y ++ + A W+ P T FTV LK
Sbjct 25941 TSR--SSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTP-PTGLQGKQFTVTKLKE 25997
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS-FWYKIDPSHTQGYRTVQLV 350
TEY FRI + +G G + + P K+ + +
Sbjct 25998 NTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVT 26057
Query 351 WKTLPPFEANGK----ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLV 406
K P E + IL + S N T+ D LT+ N
Sbjct 26058 IKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRF------DSGRYNLTLENNS 26111
Query 407 GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
G S A + + D + + ++ KD+ + + W P I + V +
Sbjct 26112 G-SKTAFVNVRVLDSPSAPVNLTIREVKKDS-VTLSWEPPLIDGGAKITNYIVEKRETTR 26169
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT-V 525
+ T+ NL E Y V G G P +K + P P V
Sbjct 26170 KAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRV 26229
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
V +N A ++W++ P I Y + +T + + E T+S LT+
Sbjct 26230 TLVDVTRNTATIKWEK-PESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAG 26288
Query 586 TLYMVRMAAYTDEGGKD 602
Y+ R+AA ++G D
Sbjct 26289 EEYVFRVAAVNEKGRSD 26305
Score = 199 bits (506), Expect = 8e-51, Method: Composition-based stats.
Identities = 118/587 (20%), Positives = 200/587 (34%), Gaps = 43/587 (7%)
Query 43 NFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTA-SSVTFTDIASLNIQL 101
V EKC + +H+ + K + + + T +S T+ + L
Sbjct 24652 PVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLL 24711
Query 102 TCNILTFGQLEQNVYGI-------TIISGLP---PEKPKNLSCIVNEGKKMRCEWD-GGR 150
N F + N YG+ ++ P P PK+L M W+
Sbjct 24712 EGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDS 24771
Query 151 ETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
+ E K + + ++ C +R T V T E V AENA G
Sbjct 24772 DGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDH-EYEFRVSAENAAGVGE 24830
Query 209 SDH--INFDPVYKV-KPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTK 264
+ + V KP PP N ++++ + S + L W P IL Y ++
Sbjct 24831 PSPATVYYKACDPVFKPGPPTNAHIVDTTKNS--ITLAWGKPIYDGGSEILGYVVEICKA 24888
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY-WSDWSEEASGITYE 323
D W + P+ T + F + L EY R+ + + G G S E
Sbjct 24889 DEEEWQIVTPQ-TGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLE 24947
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT-- 381
S K G + + +K P E +T +R + +
Sbjct 24948 APELDLDSELRKGIVVRAGGSARIHIPFKGRPTPE---------ITWSREEGEFTDKVQI 24998
Query 382 ---VNATKLTVNL--TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
VN T+L+++ ND L + N G S +A +T+ D + +K KD
Sbjct 24999 EKGVNYTQLSIDNCDRNDAGKYILKLENSSG-SKSAFVTVKVLDTPGPPQNLAVKEVRKD 25057
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV 496
+ V W P + + + ++ ++ NL E Y V
Sbjct 25058 SAFLV-WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRV 25116
Query 497 TPVYADGPGSP-ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYT 555
G G P E++ A PPS V V + A L W++ P + Y
Sbjct 25117 MAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEK-PEHDGGSRVLGYV 25175
Query 556 IFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ + + ++ +S ++ L+S Y R+ AY ++G D
Sbjct 25176 VEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSD 25222
Score = 195 bits (494), Expect = 2e-49, Method: Composition-based stats.
Identities = 116/602 (19%), Positives = 195/602 (32%), Gaps = 59/602 (10%)
Query 68 KTNHFTIPKEQYTIINRT--ASSVTFTDIASLNIQLTCNILTFGQLEQNVYGI------- 118
K +H+ + K + + + T AS V T + + L N F + N YG+
Sbjct 22513 KIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKL-LKGNEYIFRVMAVNKYGVGEPLESE 22571
Query 119 -TIISGL--PPEKPKNLSCIVNEGKKMR-CEWDGGRETHLE--TNFTLKSEWATHKFADC 172
+ PP+ PKN M C + E + + A ++ C
Sbjct 22572 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKC 22631
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV---TSDHINFDPVYKVKPNPPHNLS 229
K T V T E + AENA G + KP PP N
Sbjct 22632 NKKTLTDLRYKVSGLTEGH-EYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPR 22690
Query 230 VINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
V+++ S + + W P I Y ++ + W + P +S+T+
Sbjct 22691 VLDTSR--SSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTP-PAGLKATSYTITG 22747
Query 289 LKPFTEYVFRIRCMKEDGKGYW----SDWSEEASGITYEDRPSKAPSFWYKIDPSHT--- 341
L EY RI M +G G E + E I T
Sbjct 22748 LTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRL 22807
Query 342 ----QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL 397
+G ++ W +G+ LD + ++ S+ N + D
Sbjct 22808 FVPIKGRPAPEVKW-----ARDHGESLD-KASIESTSSYTLLIVGNVNRF------DSGK 22855
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
LTV N G S +A + + D + +K + + W P I +
Sbjct 22856 YILTVENSSG-SKSAFVNVRVLDTPGPPQDLKVKEV-TKTSVTLTWDPPLLDGGSKIKNY 22913
Query 458 CVLSDKAPCITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVYADGPGSP-ESIKAYLK 515
++ + + H+T + L E Y V G G P E+ ++
Sbjct 22914 -IVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKA 22972
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT 575
P + V +N L W++ P I Y + +T ++ A T
Sbjct 22973 SERPLPPGKITLMDVTRNSVSLSWEK-PEHDGGSRILGYIVEMQTKGSDKWATCATVKVT 23031
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLL 635
E T++ L Y R++A ++G D + P A+ +V+P L T
Sbjct 23032 EATITGLIQGEEYSFRVSAQNEKGISD--PRQLSVPVIAKD----LVIPPAFKLLFNTFT 23085
Query 636 GV 637
+
Sbjct 23086 VL 23087
Score = 193 bits (489), Expect = 1e-48, Method: Composition-based stats.
Identities = 105/577 (18%), Positives = 180/577 (31%), Gaps = 52/577 (9%)
Query 68 KTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCN-ILTFGQLEQNVYGI-------T 119
K ++ + + S T D +L N F +N+YG+
Sbjct 14741 KITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASP 14800
Query 120 IISGL---PPEKPKNLSCIVNEGKKMRCEW-DGGRETHLE-TNF-TLKSEWATHKFADCK 173
I + PP P L + W + + T + + + T K+ C
Sbjct 14801 ITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCN 14860
Query 174 AKRDTPTSCTVDYSTVYFVNIEVWVEAENALG----KVTSDHINFDPVYKVKPNPPHNLS 229
K + V AEN G +++ I P PP +
Sbjct 14861 -KMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKD-PIDPPWPPGKPT 14918
Query 230 VINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
V + + ++L WT P I Y I+ W ++ + +
Sbjct 14919 VKDVG--KTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAE---GVPTTQHLLPG 14973
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
L EY FR+R + + G+ S+ S+ PS P W ++ T
Sbjct 14974 LMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPS--PPRWLEVI---NITKNTAD 15028
Query 349 LVWKTLPPFEANGKILDYEVT---LTRWKSHLQNYTVNATKLTVNLTNDR--YLATLTVR 403
L W T+P + I +Y V + R + TV TK TV + Y+ +
Sbjct 15029 LKW-TVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAE 15087
Query 404 NLVGKSDAAVLTIPA---CDFQATHPVMDLKAFPKDNM-LWVEWTTPRESVKKYILEWCV 459
N +G+SD + F P L + ++W P+ + I + V
Sbjct 15088 NAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRY-V 15146
Query 460 LSDKAPCITDWQQEDGTVHR--TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL--- 514
+ K T W + T + ++ E V G G P L
Sbjct 15147 IEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIE 15206
Query 515 -KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNV-D 571
+PPS + G+ + W P I Y + + VN
Sbjct 15207 DPTSPPSPPLDLHVTDAGRKHIAIAWKP-PEKNGGSPIIGYHVEMCPVGTEKWMRVNSRP 15265
Query 572 SSHTEYTL-SSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
++ + + D Y++R+ A G + E +
Sbjct 15266 IKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEIS 15302
Score = 186 bits (473), Expect = 8e-47, Method: Composition-based stats.
Identities = 112/669 (17%), Positives = 207/669 (31%), Gaps = 50/669 (7%)
Query 41 HSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTD-IASLNI 99
V EK + A+ K H+ + K + + + + S + I +
Sbjct 27897 GGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTK 27956
Query 100 QLTCNILTFGQLEQNVYGI--TIISGLP--------PEKPKNLSCIVNEGKKMRCEWDGG 149
+ N F N YGI + S P P M W
Sbjct 27957 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 28016
Query 150 RETH---LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK 206
+ F K + + + + T V T + + V A NA G+
Sbjct 28017 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTE-NSDYQYRVCAVNAAGQ 28075
Query 207 VT---SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYR 262
P PP + + ++ S + L W+ P + Y ++ R
Sbjct 28076 GPFSEPSEFYKAADPIDPPGPPAKIRI--ADSTKSSITLGWSKPVYDGGSAVTGYVVEIR 28133
Query 263 TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ W+ + + T + + V +LKP Y FR+ + G+G + +E
Sbjct 28134 QGEEEEWTTVSTKGEVRT-TEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDI 28192
Query 323 EDRPSKAPSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
+ P + G V + +K PP + + + S +
Sbjct 28193 LEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDS 28252
Query 382 VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
+ + ND LT+ N VG+ ++ +++ D A + +K + + +
Sbjct 28253 SSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLL 28312
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVY 500
W P I+ + + A T W T + +L+E + V
Sbjct 28313 -WDPPLIDGGSPIINYVIEKRDATKRT-WSVVSHKCSSTSFKLIDLSEKTPFFFRVLAEN 28370
Query 501 ADGPGSP-ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
G G P E+ + P+ + K K +L W + D I Y + +
Sbjct 28371 EIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFD-GGSVITEYVVERK 28429
Query 560 TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD----GP---EFTFTTPK 612
+ S E +S L ++ R+ A ++G D GP + TP+
Sbjct 28430 GKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPE 28489
Query 613 FAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPP 672
+I V V + ++ + + P PS S + P
Sbjct 28490 VDLSDIPGAQVTVRIGH---------------NVHLELPYKGKPKPSISWLKDGLPLKES 28534
Query 673 RHNFNSKDQ 681
SK +
Sbjct 28535 EFVRFSKTE 28543
Score = 183 bits (465), Expect = 8e-46, Method: Composition-based stats.
Identities = 107/576 (19%), Positives = 184/576 (32%), Gaps = 58/576 (10%)
Query 65 IVWK--TNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNI--------LTFGQLEQN 114
I WK + Y I + + + S + + TC + F +N
Sbjct 17858 ISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAEN 17917
Query 115 VYGI--TIISGL--------PPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTL-KS 162
+YGI ++S P+ P W+ + TN+ L K
Sbjct 17918 LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKR 17977
Query 163 EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN---FDPVYK 219
E + ++A P + + E V AEN +G + F
Sbjct 17978 ETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPI 18037
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
KP+PP N I++ S + LTW P IL Y ++Y+ W + +
Sbjct 18038 AKPSPPVNPEAIDTTCNS--VDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 18095
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+ + V L+ Y FR+ + G+ + E + P +
Sbjct 18096 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQ 18155
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN--------ATKLTVN 390
H + T++L I WK ++ +KL +
Sbjct 18156 -HIKVGDTLRLS----------AIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIR 18204
Query 391 L--TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE 448
D + +LTV N G S + + D +++ KD+ ++ W P +
Sbjct 18205 NAAHEDGGIYSLTVENPAG-SKTVSVKVLVLDKPGPPRDLEVSEIRKDSC-YLTWKEPLD 18262
Query 449 SVKKYILEWCVLSDKAPCITDWQQEDGT-VHRTYLRGNLAESKCYLITVTPVYADGPGS- 506
I + V+ + W T +++ +L E YL V G G
Sbjct 18263 DGGSVITNY-VVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPF 18321
Query 507 ---PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
P+ IKA PP + V K E L W++ P I Y + Y+
Sbjct 18322 VETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNK-PDRDGGSPITGYLVEYQEEGT 18380
Query 564 NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ ++ E ++ L Y R+ A G
Sbjct 18381 QDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVG 18416
Score = 183 bits (463), Expect = 1e-45, Method: Composition-based stats.
Identities = 95/551 (17%), Positives = 172/551 (31%), Gaps = 25/551 (5%)
Query 59 HVNANYIVW-KTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYG 117
+ W K + Q + + + ++ + N+
Sbjct 26060 GRPEPEVKWEKAEGILTDRAQIEVTSSFTM-LVIDNVTRFDSGRY-NLTLENNSGSKTAF 26117
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAK 175
+ + P P NL+ + + W+ TN+ ++ T K
Sbjct 26118 VNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITN 26177
Query 176 RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
T T+ ++ V A N G P PP +++++
Sbjct 26178 NCTKTTFRIENLQEGCSYY-FRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR 26236
Query 236 LSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
++ +K W P S I Y ++ +TK + WS T T+ L E
Sbjct 26237 NTATIK--WEKPESDGGSKITGYVVEMQTKGSEKWSTC----TQVKTLEATISGLTAGEE 26290
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
YVFR+ + E G+ E +PS F + Q + + +K
Sbjct 26291 YVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK--IDVPFKGR 26348
Query 355 PPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVL 414
P N + + T + + TV + + D L V N G +
Sbjct 26349 PQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPI- 26407
Query 415 TIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED 474
TI D + + D+ + + W P I + ++ K T W
Sbjct 26408 TIIVLDRPGPPGPIRIDEVSCDS-ITISWNPPEYDGGCQISNY-IVEKKETTSTTWHIVS 26465
Query 475 GTVHRTYLR-GNLAESKCYLITVTPVYADGPGSPESIKAYLKQ---APPSKGPTVRTKKV 530
V RT ++ L Y V G S A + + +PP T +
Sbjct 26466 QAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHA 26525
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG--NETAVNVDSSHTEYTLSSLTSDTLY 588
K+ ++ W Q+PV+ + Y + Y+ A + + T+ +S L +Y
Sbjct 26526 TKSTMLVTW-QVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMY 26584
Query 589 MVRMAAYTDEG 599
R+ A G
Sbjct 26585 EYRVYAENIAG 26595
Score = 183 bits (463), Expect = 1e-45, Method: Composition-based stats.
Identities = 99/586 (17%), Positives = 178/586 (30%), Gaps = 40/586 (7%)
Query 38 VQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASL 97
+++ ++K V + WK P + + S + + A
Sbjct 18157 IKVGDTLRLSAIIK-------GVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHE 18209
Query 98 NIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-- 155
+ + ++ + ++ P P++L W +
Sbjct 18210 DGGIY-SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVI 18268
Query 156 TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT----SDH 211
TN+ ++ + V AEN G+
Sbjct 18269 TNYVVERRDVAS-AQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKP 18327
Query 212 IN-FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDASTW 269
I DP++ P PP +L + + + + L W P I Y ++Y+ + W
Sbjct 18328 IKALDPLH--PPGPPKDLH--HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDW 18383
Query 270 SQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
+ T V L+ Y FR++ G G D + PS
Sbjct 18384 IKFK----TVTNLECVVTGLQQGKTYRFRVKAENIVGLGLP-DTTIPIECQEKLVPPSVE 18438
Query 330 PSFWYKIDPSHTQGYRTVQL--VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKL 387
I+ + TV+ + + +P A E+ + + + +
Sbjct 18439 LDV-KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTI 18497
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAV-LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
L D +TV N G AV LT+ T P+ L P + + W P
Sbjct 18498 KNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTP--EHMTISWQPP 18555
Query 447 RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPG 505
++ ++ + V T W +T L+ +L + Y+ V G G
Sbjct 18556 KDDGGSPVINYIVEKQDTRKDT-WGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVG 18614
Query 506 SP---ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII 562
P A K +PPS + +N A + W LP I Y + R +
Sbjct 18615 PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWT-LPKSDGGSPITGYYMERREVT 18673
Query 563 GNETAVN-VDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEF 606
G VN + ++ ++ L Y R+ A G K P
Sbjct 18674 GKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSS 18719
Score = 182 bits (462), Expect = 2e-45, Method: Composition-based stats.
Identities = 107/576 (19%), Positives = 166/576 (29%), Gaps = 51/576 (9%)
Query 70 NHFTIPKEQYTIINRTASSVTFTDIASLNIQLT--------CNILTFGQLEQNVYGI--- 118
N +P Y + R S T+ ++A+ I+ T F QN YG+
Sbjct 22112 NDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPG 22171
Query 119 ----TIISGLP---PEKPKNLSCIVNEGKKMRCEWD-GGRETHLE-TNFTLKSEWATHKF 169
I++ P P P M W + + ++ +
Sbjct 22172 ITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGIL 22231
Query 170 ADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS 229
+K P + + E V AEN GK + + +PP
Sbjct 22232 WQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKP- 22290
Query 230 VINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
+ + L W P I Y ++ R W + + + FTV
Sbjct 22291 -VPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNIL--ENEFTVSG 22347
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR--- 345
L Y FR+ G S SE + IT D +AP + T +
Sbjct 22348 LTEDAAYEFRVIAKNAA--GAISPPSEPSDAITCRD-DVEAPKIKVDVKFKDTVILKAGE 22404
Query 346 ----TVQLVWKTLPPFEAN--GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT 399
+ + P E + GK L+ L + VN D T
Sbjct 22405 AFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDST----RRDSGAYT 22460
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
LT N G + + + + + + W P + I + V
Sbjct 22461 LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCV-LSWFPPLDDGGAKIDHYIV 22519
Query 460 LSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPGSP---ESIKAYLK 515
+ + W V T L+ L + Y+ V V G G P E + A
Sbjct 22520 QKRETSRLA-WTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNP 22578
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSS 573
PP + K+ V+ W P I NY + R G +
Sbjct 22579 YGPPDPPKNPEVTTITKDSMVVCWGH-PDSDGGSEIINYIVERRDKAGQRWIKCNKKTLT 22637
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTF 608
Y +S LT Y R+ A G P F
Sbjct 22638 DLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPF 22673
Score = 178 bits (452), Expect = 3e-44, Method: Composition-based stats.
Identities = 104/614 (17%), Positives = 195/614 (32%), Gaps = 56/614 (9%)
Query 24 LLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIIN 83
+ C + P + EKC + +++ + K + + +
Sbjct 26800 VAVNCKVLDKPGP--PAG-PLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLA 26856
Query 84 RTASSVTFTDIASLNIQLT----CNILTFGQLEQNVYGIT-------IISGLP---PEKP 129
T ++ + ++T N F N YG+ I + P P P
Sbjct 26857 WTICE---GELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPP 26913
Query 130 KNLSCIVNEGKKMRCEWD-GGRETH--LETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+L + M W + + + E + ++ K
Sbjct 26914 TSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTG 26973
Query 187 STVYFVNIEVWVEAENALG-KVTS--DHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
E V AENA G + S + P+PP +++S + + +
Sbjct 26974 LREG-CEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSG--KTTITIA 27030
Query 244 WTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
W P I Y ++Y+ D + W + +T+ L EYVFR++ +
Sbjct 27031 WVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL---RGTEYTISGLTTGAEYVFRVKSV 27087
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSF-WYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ G SD S+ E+ P K T+ + ++ P
Sbjct 27088 NKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLW 27147
Query 362 KILDYEVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
D ++ + + T + T LT+ ND TLT++N++ + L +
Sbjct 27148 SKPDTDLRTRAYV----DTTDSRTSLTIENANRNDSGKYTLTIQNVLSA-ASLTLVVKVL 27202
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
D + ++ K++ + + W P + + + +A W +R
Sbjct 27203 DTPGPPTNITVQDVTKESAV-LSWDVPENDGGAPVKNYHIEKREA-SKKAWVSVTNNCNR 27260
Query 480 -TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP-----PSKGPTVRTKKVGKN 533
+Y NL E Y V+ G G P K+ PS + + K+
Sbjct 27261 LSYKVTNLQEGAIYYFRVSGENEFGVGIPAE----TKEGVKITEKPSPPEKLGVTSISKD 27316
Query 534 EAVLEWDQLPVDVQNG-FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
L W L + G I +Y + + T + +S L ++ Y R+
Sbjct 27317 SVSLTW--LKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRV 27374
Query 593 AAYTDEGGKDGPEF 606
A G D E
Sbjct 27375 FAENQAGLSDPREL 27388
Score = 175 bits (444), Expect = 3e-43, Method: Composition-based stats.
Identities = 118/608 (19%), Positives = 201/608 (33%), Gaps = 72/608 (12%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWK--TNHFTIPKEQYTIINRTASSVT 90
PE PVV V EKC + WK Y + R S +
Sbjct 23567 PEGPVVISG-------VTAEKCT---------LAWKPPLQDGGSDIINYIVERRETSRLV 23610
Query 91 FT----DIASLNIQLT----CNILTFGQLEQNVYGI-------TIISGLP---PEKPKNL 132
+T ++ +L+ ++T N TF + N YG+ +++ P P+ PK
Sbjct 23611 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 23670
Query 133 SCIVNEGKKMRCEWDGGRETH---LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
M W+ + K + ++ C + V +
Sbjct 23671 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTG-LI 23729
Query 190 YFVNIEVWVEAENALGKVTSDHINF-----DPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ E V AENA G + DP+Y KP PP+N VI+ S + L+W
Sbjct 23730 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIY--KPGPPNNPKVIDITR--SSVFLSW 23785
Query 245 TNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
+ P I Y ++ W+ P T +++ V+ L EY FRI +
Sbjct 23786 SKPIYDGGCEIQGYIVEKCDVSVGEWTMCTP-PTGINKTNIEVEKLLEKHEYNFRICAIN 23844
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFW-YKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
+ G G +D + P KI G + + K P E
Sbjct 23845 KAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPE---- 23900
Query 363 ILDYEVTLTRWKSHLQNYTVN--ATKLTVNLT-----NDRYLATLTVRNLVGKSDAAVLT 415
V + +++ + + T + D TLT+ N G +A +T
Sbjct 23901 -----VKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGT-KSAFVT 23954
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
+ D + + + KD+ + + W P I + V +A +
Sbjct 23955 VRVLDTPSPPVNLKVTEITKDS-VSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTN 24013
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT-VRTKKVGKNE 534
++ L E Y VT G G P +K A + P + V +N
Sbjct 24014 CHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNS 24073
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
L W + P I Y + + + + + +++LT Y+ R+ A
Sbjct 24074 VSLSWTK-PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVA 24132
Query 595 YTDEGGKD 602
++G D
Sbjct 24133 VNEKGRSD 24140
Score = 175 bits (444), Expect = 3e-43, Method: Composition-based stats.
Identities = 97/519 (19%), Positives = 167/519 (32%), Gaps = 55/519 (11%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHKFADCKAK 175
I + P PK L + W+ + T + ++ + K
Sbjct 14407 IDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMD 14466
Query 176 RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS----DHINFDPVYKVKPNPPHNLSVI 231
T TV V V A N G + +N V P+PP N V
Sbjct 14467 FVTDLEFTVP-DLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATV-PDPPEN--VK 14522
Query 232 NSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ ++ + LTW P + I Y ++ + + W E A T+ V L+
Sbjct 14523 WRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVA-CGEPVAETKME--VTGLE 14579
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID-----------PS 339
Y +R++ + G S +EE + ++ P P+
Sbjct 14580 EGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPA 14639
Query 340 HTQGYRTVQLVW-KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL-TNDRYL 397
G ++ W K + + +I ++N +T V+ +D
Sbjct 14640 TVTGKPEPKITWTKADMILKQDKRI------------TIENVPKKSTVTIVDSKRSDTGT 14687
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
+ N+ G+ AV+ + D D+ ++ L + W PR+ I +
Sbjct 14688 YIIEAVNVCGR-ATAVVEVNVLDKPGPPAAFDITDVTNESCL-LTWNPPRDDGGSKITNY 14745
Query 458 CVLSDKAPCITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVYADGPGSP---ESIKAY 513
V+ +A W + TV T + L +K Y+ V G G P I A
Sbjct 14746 -VVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAK 14804
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV--- 570
+ PP + + K+ L W + P D I Y + + +T V
Sbjct 14805 YQFDPPGPPTRLEPSDITKDAVTLTWCE-PDDDGGSPITGY---WVERLDPDTDKWVRCN 14860
Query 571 --DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
T Y + LT+ Y R+ A G + T
Sbjct 14861 KMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKST 14899
Score = 173 bits (439), Expect = 1e-42, Method: Composition-based stats.
Identities = 97/565 (17%), Positives = 168/565 (30%), Gaps = 41/565 (7%)
Query 75 PKEQYTIINRTASSVTFTDIASLNIQLTC--------NILTFGQLEQNVYGI-------T 119
Y + R S + +++ +C + F +N YG+
Sbjct 20346 EITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEP 20405
Query 120 IISGLPPEKPKNLSCIVNEGKK-----MRCEWDGGRETH--LETNFTLKSEWATHKFADC 172
I+ P + P C M W + T + L+
Sbjct 20406 AIAKNPYDPPGR--CDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK 20463
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK---PNPPHNLS 229
++ E V A N G + + P PP
Sbjct 20464 VNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPK 20523
Query 230 VINSEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
V ++ S + L+W P+ I+ Y ++ + D+ W + ++ F V
Sbjct 20524 VYDTTR--SSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL-QKTRFEVTG 20580
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
L T+Y FR+ + + G SD ++ P + G T++
Sbjct 20581 LMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGV-TMR 20639
Query 349 LVW--KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLV 406
L K PP + + + + D LT+ N
Sbjct 20640 LYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSC 20699
Query 407 GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
GK + + D + +K KD+ +V W P I+ + V A
Sbjct 20700 GK-KEYTIVVKVLDTPGPPVNVTVKEISKDSA-YVTWEPPIIDGGSPIINYVVQKRDAE- 20756
Query 467 ITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA-PPSKGPT 524
W +T + NL E K Y V G G P + +K + P
Sbjct 20757 RKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVD 20816
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTS 584
++ + V K+ + W + D I Y + + T V S +Y+ LT
Sbjct 20817 LKVRSVSKSSCSIGWKKPHSD-GGSRIIGYVVDFLTEENKWQRVMKSLS-LQYSAKDLTE 20874
Query 585 DTLYMVRMAAYTDEGGKDGPEFTFT 609
Y R++A + G E T
Sbjct 20875 GKEYTFRVSAENENGEGTPSEITVV 20899
Score = 171 bits (433), Expect = 6e-42, Method: Composition-based stats.
Identities = 114/624 (18%), Positives = 200/624 (32%), Gaps = 57/624 (9%)
Query 69 TNHFTIPKEQYTIINRTA-SSVTFTDIASLNIQLTCNILTFGQLEQNVYGITII-SGLP- 125
++ + K + + + S+ T ++ + N F +N G P
Sbjct 19255 IQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPV 19314
Query 126 --------PEKPKNLSCIVNEGKKMRCEWDGGRETH---LETNFTLKSEWATHKFADCKA 174
P +P ++M W+ + F K E + ++
Sbjct 19315 IAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVP-VN 19373
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALG----KVTSDHINFDPVYKVKPNPPHNLSV 230
K P + + + V+AEN +G + S + P PP N V
Sbjct 19374 KSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPV-VAKDPIEPPGPPTNFRV 19432
Query 231 INSEELSSILKLTWTNPS-IKSVIILKYNIQYRTK--DASTWSQIPPEDTAST--RSSFT 285
+++ + S + L W P I+ Y ++ R K DAS + A+ R FT
Sbjct 19433 VDTTKHS--ITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFT 19490
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
V L EY FR+ + G G ++ E + P +
Sbjct 19491 VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDA-SMRKLVIVRAGC 19549
Query 346 TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN---DRYLATLTV 402
++L + K+ +V + Q V+ V + D +LT+
Sbjct 19550 PIRLF--AIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTL 19607
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD 462
N G+ A + + D + + K + V W P + + ++
Sbjct 19608 VNPAGE-KAVFVNVRVLDTPGPVSDLKVSDVTKTSC-HVSWAPPENDGGSQVTHY-IVEK 19664
Query 463 KAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPG----SPESIKAYLKQA 517
+ W V +T NL Y VT V GPG P+ + A +
Sbjct 19665 READRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLS 19724
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG---NETAVNVDSSH 574
P + ++ KN A L W P+ I Y YR T +V
Sbjct 19725 EPDPPRKLEVTEMTKNSATLAWLP-PLRDGGAKIDGYITSYREEEQPADRWTEYSV-VKD 19782
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTL 634
++ L Y R+AA G + P+ A+G EA + L+
Sbjct 19783 LSLVVTGLKEGKKYKFRVAARNAVG--------VSLPREAEGVYEAKEQLLPPKILMPEQ 19834
Query 635 LGVLFCFNKRDLIKKHIWPNVPDP 658
+ + K+ I+ H++ P P
Sbjct 19835 ITIKAG--KKLRIEAHVYGK-PHP 19855
Score = 170 bits (429), Expect = 2e-41, Method: Composition-based stats.
Identities = 91/592 (15%), Positives = 164/592 (28%), Gaps = 37/592 (6%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P P F + + C +H+ ++ + K + + + + T
Sbjct 19921 PPQP------PFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVT 19974
Query 93 DIA-SLNIQLTCNILTFGQLEQNVYGITIISGLP----------PEKPKNLSCIVNEGKK 141
+ + + F +N +GI+ P P +PKN
Sbjct 19975 KTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDC 20034
Query 142 MRCEWD-GGRETHLETN-FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
+ WD + + ++ + ++ V + +
Sbjct 20035 IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIY 20094
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYN 258
A N G ++ +PP VI+ S + L W P I+ Y
Sbjct 20095 ALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDV--TKSTVSLIWARPKHDGGSKIIGYF 20152
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
++ W + + +T L+ +Y FR S+ S+ +
Sbjct 20153 VEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVT 20212
Query 319 GITYEDRPSKAPSFWYK---IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
+ P S K + T + K +P K +
Sbjct 20213 ILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVS--WKKDGTLLKPAEGIK 20270
Query 376 HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK 435
+ +L D T+T N G S +A + + D + +
Sbjct 20271 MAMQRNLCTLELFSVNRKDSGDYTITAENSSG-SKSATIKLKVLDKPGPPASVKINKM-Y 20328
Query 436 DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH-RTYLRGNLAESKCYLI 494
+ + W P E I + ++ + +W Q TV + L E Y
Sbjct 20329 SDRAMLSWEPPLEDGGSEITNY-IVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQF 20387
Query 495 TVTPVYADGPGSP---ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
+ G G P E A PP + + K+ + W P D I
Sbjct 20388 RICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKP-PADDGGSPI 20446
Query 552 RNYTIFYRTIIG-NETAVN-VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
Y + R N T VN + L T Y R+ A G
Sbjct 20447 TGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPG 20498
Score = 169 bits (427), Expect = 3e-41, Method: Composition-based stats.
Identities = 104/591 (18%), Positives = 199/591 (34%), Gaps = 37/591 (6%)
Query 44 FTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQL-T 102
T V +EKC + + + H+ + + + + +N ++ + +L
Sbjct 30074 LTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIK 30133
Query 103 CNILTFGQLEQNVYGITIISGL-------------PPEKPKNLSCIVNEGKKMRCEW-DG 148
N F N YG + PP P+ + + + +W
Sbjct 30134 NNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEV---GTGKEHIIIQWTKP 30190
Query 149 GRETHLE-TNFTL-KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK 206
+ E +N+ + K E + ++ + S + + + V A NA G
Sbjct 30191 ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN 30250
Query 207 VTSDHINFDPVYKVK---PNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYR 262
+ + P PP V+++ + S + L WT P I+ Y ++ +
Sbjct 30251 SEPSEASNFISCREPSYTPGPPSAPRVVDTTKHS--ISLAWTKPMYDGGTDIVGYVLEMQ 30308
Query 263 TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
KD W ++ + + FTV DLK +Y FR+ + G +S+ E +
Sbjct 30309 EKDTDQWYRV-HTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVER 30367
Query 323 EDRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
+ P + K + G + + PP ++ ++Y+
Sbjct 30368 IEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYS 30427
Query 382 VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
+ + D T+ N GK +A + + D P + +K +D+ + +
Sbjct 30428 LLI--VDKVNRYDAGKYTIEAENQSGK-KSATVLVKVYDTPGPCPSVKVKEVSRDS-VTI 30483
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
W P + + V +A Y L E Y V P
Sbjct 30484 TWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENI 30543
Query 502 DGPGSP-ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G G P E+ A L P + V K+ L W++ P+ + Y +
Sbjct 30544 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEK-PLYDGGSRLTGYVLEACK 30602
Query 561 IIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT 609
V + + E+T++SL Y+ R+ A ++G + P T T
Sbjct 30603 AGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVT 30652
Score = 168 bits (426), Expect = 5e-41, Method: Composition-based stats.
Identities = 107/618 (17%), Positives = 188/618 (30%), Gaps = 39/618 (6%)
Query 18 TESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKE 77
T S G + I E P + V + + + A + +++ + K
Sbjct 25314 TNSAGTATENLSVIVLEKPGPPVG-PVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKR 25372
Query 78 QYTIINRTASSVTFTDIASLNIQL-TCNILTFGQLEQNVYGIT-------IISGLP---P 126
T S T +L T F +N YG + +I P P
Sbjct 25373 DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEP 25432
Query 127 EKPKNLSCIVNEGKKMRCEWD-GGRETHLETN-FTLKSEWATHKFADCKAKRDTPTSCTV 184
P +M +W + + + L+ + K +
Sbjct 25433 GPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFK 25492
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ E V AEN +G ++ V + +PP I + + L W
Sbjct 25493 TTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNN--VTLKW 25550
Query 245 TNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
P+ I Y ++ + W + + + FTV L Y FR+
Sbjct 25551 KKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVL--ETEFTVSGLVEDQRYEFRVIARN 25608
Query 304 EDGKGYWSDWSEEASGITYED---RPSKAPSFWYKIDPSHTQGYRTVQ---LVWKTLPPF 357
G +S+ S+ + IT D P+ + YK G V + K +P
Sbjct 25609 AA--GNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIP-- 25664
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATKLTVN-LTNDRYLATLTVRNLVGKSDAAVLTI 416
+ E+ T + +++ T + + + D L + N+ G +
Sbjct 25665 DVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVK 25724
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
+ + + ++ W P + I + ++ + W Q
Sbjct 25725 VLDRPGPPEGPLKVTGVTAEKC-YLAWNPPLQDGGANISHY-IIEKRETSRLSWTQVSTE 25782
Query 477 VHRT-YLRGNLAESKCYLITVTPVYADGPGSP---ESIKAYLKQAPPSKGPTVRTKKVGK 532
V Y L Y+ V V G G P + A PP T + K
Sbjct 25783 VQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITK 25842
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDS-SHTEYTLSSLTSDTLYMV 590
+ V+ W PVD I Y + R G T N + + ++ LT Y
Sbjct 25843 DSMVVTW-ARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEF 25901
Query 591 RMAAYTDEGGKDGPEFTF 608
R+AA G + E +
Sbjct 25902 RVAAENAAGVGEPSEPSV 25919
Score = 168 bits (425), Expect = 6e-41, Method: Composition-based stats.
Identities = 106/606 (17%), Positives = 188/606 (31%), Gaps = 75/606 (12%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTI------INRTASSVTFTDIASLNI-QLTCNILTF 108
D + I W N I K + ++R+ + + ++ + T +
Sbjct 16348 DVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTAS 16407
Query 109 GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWAT 166
+L + + P P+NL+ + + WD + T++ + A+
Sbjct 16408 NRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDAS 16467
Query 167 HKFADCKAKRDTPTSCTVDYSTVYFV---NIEVWVEAENALGKV---TSDHINFDPVYKV 220
K + + T T+ Y + E V A N G SD + Y++
Sbjct 16468 RK--KAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRL 16525
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTAS 279
P PP V+ + ++WT P I Y ++ R + + WS++
Sbjct 16526 -PGPPGKPKVLAR--TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITK 16582
Query 280 ---TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
F V L +Y FR + G G S+ S+ P PS
Sbjct 16583 VGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDP-IFPPGPPSCPEVK 16641
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH------LQNYTVNATKLTVN 390
D + ++ L WK P + I Y V + + + + + V
Sbjct 16642 D----KTKSSISLGWKP-PAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVP 16696
Query 391 LTND--RYLATLTVRNLVGKSDAAVLT--IPACDFQATHPV------MDLKAFPKDNMLW 440
+ +Y + N G+S+ + T IPA D Q V D + +
Sbjct 16697 NLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIR 16756
Query 441 V------------EWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+ W ++++K + + + R++
Sbjct 16757 IPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHT--- 16813
Query 486 LAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
Y IT + P ++ + + L W +P D
Sbjct 16814 ----GKYSITAKNKAGQKTANCRVKVMD----VPGPPKDLKVSDITRGSCRLSWK-MPDD 16864
Query 546 VQNGFIRNYTIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
I+ Y I RTI G T VN D T + + L S+ Y R+ A G P
Sbjct 16865 DGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGP-P 16923
Query 605 EFTFTT 610
T
Sbjct 16924 VETIQR 16929
Score = 167 bits (423), Expect = 9e-41, Method: Composition-based stats.
Identities = 121/681 (18%), Positives = 226/681 (33%), Gaps = 77/681 (11%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCT 183
P P ++ + W+ E TN+ + + + TSC+
Sbjct 20316 PGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCS 20375
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDP-VYKVKPNPPH--NLSVINSEELSSIL 240
V+ + + AEN G D + +P + K +PP + VI S +
Sbjct 20376 VEKLIEGH-EYQFRICAENKYGVG--DPVFTEPAIAKNPYDPPGRCDPPVI-SNITKDHM 20431
Query 241 KLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
++W P I Y ++ R A W+++ + + L+ TEY FR+
Sbjct 20432 TVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPII--ERTLKATGLQEGTEYEFRV 20489
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
+ + G G SD S+ A + P P+F D + + +V L W P ++
Sbjct 20490 TAINKAGPGKPSDASKAAYARDPQYPP-GPPAFPKVYDTTRS----SVSLSW-GKPAYDG 20543
Query 360 NGKILDYEVTLTRWKSHLQ---NYTVNATKLTVNLTN----DRYLATLTVRNLVGKSDAA 412
I+ Y V + R S N N K +T +Y + N +G SD +
Sbjct 20544 GSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPS 20603
Query 413 VLTIPACDFQA---THPVMDLKAFPKDNMLW-----------VEWTTPRESVKKYILEWC 458
+P + P +L A + ++ V+ P + + W
Sbjct 20604 --DVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPK------ITWS 20655
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAES--KCYLITVTPVYADGPGSPESIKAYLKQ 516
+ + N+ + Y++T+ + G E
Sbjct 20656 KPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTL----ENSCGKKEYTIVVKVL 20711
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNVDSSHT 575
P V K++ K+ A + W+ P+ I NY + R + V + S T
Sbjct 20712 DTPGPPVNVTVKEISKDSAYVTWEP-PIIDGGSPIINYVVQKRDAERKSWSTVTTECSKT 20770
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLL 635
+ +++L Y R+ A + G D P T K +Q + + V + +
Sbjct 20771 SFRVANLEEGKSYFFRVFAENEYGIGD-PGETRDAVKASQTPGPVVDLKVRSVSKSSCSI 20829
Query 636 GV----------LFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF----NSKDQ 681
G + + L +++ W V KS Q+S S +
Sbjct 20830 GWKKPHSDGGSRIIGYVVDFLTEENKWQRV---MKSLSLQYSAKDLTEGKEYTFRVSAEN 20886
Query 682 MYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSI 741
+G ++++VV + DL L + E + + +
Sbjct 20887 ENGEGTPSEITVVARDDVVAP----DLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 20942
Query 742 SSSDENESSQNTSSTVQYSTV 762
E+ + +T +V+ S V
Sbjct 20943 WKKGEDPLATDTRVSVESSAV 20963
Score = 166 bits (421), Expect = 2e-40, Method: Composition-based stats.
Identities = 94/556 (17%), Positives = 169/556 (30%), Gaps = 28/556 (5%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNI-QLTCNILTFGQLEQN 114
+ W I + + +S+ ++ + + T + +
Sbjct 23892 PIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSA 23951
Query 115 VYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLET--NFTLKSEWATHKFADC 172
+T+ P P NL + W+ N+ ++ AT K
Sbjct 23952 F--VTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 24009
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
S +D V AEN G P PP ++V +
Sbjct 24010 VVTNCHKNSWKIDQLQEGCSYY-FRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDD 24068
Query 233 SEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
S + L+WT P I++Y ++ + K + WS E + +L
Sbjct 24069 VTRNS--VSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWS----ECARVKSLQAVITNLTQ 24122
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
EY+FR+ + E G+ + P P+F V +
Sbjct 24123 GEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISG 24182
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT--NDRYLATLTVRNLVGKS 409
+ P L L + +++ T L++ T +D +TV N+VG+
Sbjct 24183 RPKPTITWTKDGL----PLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQK 24238
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITD 469
A++ + + ++ + + W P + I + V T
Sbjct 24239 TASIEIVTLDKPDPPKGPVKFDDVSAES-ITLSWNPPLYTGGCQITNYIVQKRDT-TTTV 24296
Query 470 WQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPG---SPESIKAYLKQAPPSKGPTV 525
W TV RT L+ L Y + G + I A P T
Sbjct 24297 WDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTP 24356
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDSSH-TEYTLSSLT 583
+ K+ V++W PV+ + Y + + T VN H T++ +L
Sbjct 24357 FATAISKDSMVIQW-HEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLE 24415
Query 584 SDTLYMVRMAAYTDEG 599
Y R+ A G
Sbjct 24416 EGIEYEFRVYAENIVG 24431
Score = 166 bits (419), Expect = 3e-40, Method: Composition-based stats.
Identities = 102/592 (17%), Positives = 169/592 (29%), Gaps = 50/592 (8%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTD 93
+ VV + T + Y W + + + S
Sbjct 13934 QDLVVDVGKPLTM-------VVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEA 13986
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD-GGRET 152
+ + + I + P +NL ++ W+ +
Sbjct 13987 KKGDKGRYKIVLQNKHGKAEGF--INLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDG 14044
Query 153 HLETN-FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD- 210
+ + ++ K R TV V V A N +G
Sbjct 14045 GSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVE 14104
Query 211 ---HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDA 266
+ Y V P PP N+++ + + LTW P I Y I+ R K +
Sbjct 14105 TDNPVEARSKYDV-PGPPLNVTITDVNRFG--VSLTWEPPEYDGGAEITNYVIELRDKTS 14161
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
W S TV D+ EY FR+R G G S + +RP
Sbjct 14162 IRWDTAMTVRAED--LSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERP 14219
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ------NY 380
S + S Q +VQL W+ P + IL Y +
Sbjct 14220 SPPVNL-----TSSDQTQSSVQLKWEP-PLKDGGSPILGYIIERCEEGKDNWIRCNMKLV 14273
Query 381 TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP-ACDFQATHPVMDLKA------- 432
K+T ++YL ++ N G SD + + P D P MDL A
Sbjct 14274 PELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEV 14333
Query 433 -FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
P + V T + VL + ++
Sbjct 14334 IVPNPITILVPSTGYPRPTATWCFGDKVLETGDR--VKMKTLSAYAELVISPSERSDKGI 14391
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
Y + + G I + A PS ++ + K+ L W+ P D +
Sbjct 14392 YTLKLENRVKTISG---EIDVNVI-ARPSAPKELKFGDITKDSVHLTWEP-PDDDGGSPL 14446
Query 552 RNYTIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
Y + R + T V + E+T+ L Y+ ++ A G +
Sbjct 14447 TGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGE 14498
Score = 165 bits (418), Expect = 4e-40, Method: Composition-based stats.
Identities = 85/516 (16%), Positives = 148/516 (29%), Gaps = 43/516 (8%)
Query 119 TIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN--FTLKSEWATHKFADCKAKR 176
+ P PK+L R W + + + ++ K K
Sbjct 16832 RVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAW-TKVNP 16890
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL-SVINSEE 235
D ++ V + V AEN G + PP +
Sbjct 16891 DCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLI 16950
Query 236 LSSILKLTWTNP-SIKSVIILKYNIQYRTKD-----ASTWSQIPPEDTASTRSSFTVQDL 289
+ + L+W P + + Y ++ D W Q D FTV+DL
Sbjct 16951 TKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVE--ELQFTVEDL 17008
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID-------PSHTQ 342
EY FR++ + G S + PS + +++ + +
Sbjct 17009 VEGGEYEFRVKAVNAAGVSKPSATVGPVTVKDQTCPPSIDLKEFMEVEEGTNVNIVAKIK 17068
Query 343 GYRTVQLVW-KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV---NLTNDRYLA 398
G L W K P N + + Y +H+ V+ T V + +D L
Sbjct 17069 GVPFPTLTWFKAPPKKPDNKEPVLY-------DTHVNKLVVDDTCTLVIPQSRRSDTGLY 17121
Query 399 TLTVRNLVGK-SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
T+T N +G S L + P+ + + + W P++ I +
Sbjct 17122 TITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESV--SADQMTLSWFPPKDDGGSKITNY 17179
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP---ESIKAYL 514
+ +A T TY L E Y+ + G G P E A
Sbjct 17180 VIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARN 17239
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH 574
+ P V +N + W++ P + Y + +
Sbjct 17240 LFSVPGAPDKPTVSSVTRNSMTVNWEE-PEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPI 17298
Query 575 T------EYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
Y ++ L + Y R+ A G
Sbjct 17299 KAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPAS 17334
Score = 165 bits (417), Expect = 5e-40, Method: Composition-based stats.
Identities = 93/602 (15%), Positives = 184/602 (31%), Gaps = 35/602 (6%)
Query 41 HSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQ 100
S T V K W+T T+ + T+ T S+ +A+ N
Sbjct 15039 GSPITNYIVEKRDVRRKG--------WQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAI 15090
Query 101 LTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNF 158
+ E +V + P P L+ + + + +W+ + +
Sbjct 15091 GQSDYTEI---EDSVLAKDTFTT--PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRY 15145
Query 159 TLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-TSDHINFDPV 217
++ + K P + ++ V AEN G S+ +
Sbjct 15146 VIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSI 15205
Query 218 YKV--KPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPP 274
P+PP +L V ++ + + W P I+ Y+++ W ++
Sbjct 15206 EDPTSPPSPPLDLHVTDAGRK--HIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNS 15263
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
+ + + P EYV R+R + G S+ SE + +P+
Sbjct 15264 RPIKDLKFKVE-EGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHD 15322
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND 394
I + ++ + ++ +P + EV + + ++ ++ ++ D
Sbjct 15323 IIVIEGEKL--SIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRAD 15380
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI 454
+ T+T+ N +G S A + + + K + + W P I
Sbjct 15381 AGIYTITLENKLG-SATASINVKVIGLPGPCKDIKASDITKSSC-KLTWEPPEFDGGTPI 15438
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG----SPESI 510
L + + +A T G ++ +L + Y V V G G +
Sbjct 15439 LHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPV 15498
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
A + PP V + W P+ I Y I + G E
Sbjct 15499 IAQDPKQPPDPPVDVEVHNPTAEAMTITWKP-PLYDGGSKIMGYIIE-KIAKGEERWKRC 15556
Query 571 DS---SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
+ YT L Y R+ A G + T T + +++ L
Sbjct 15557 NEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSL 15616
Query 628 AF 629
Sbjct 15617 EV 15618
Score = 163 bits (413), Expect = 1e-39, Method: Composition-based stats.
Identities = 108/607 (18%), Positives = 184/607 (30%), Gaps = 51/607 (8%)
Query 72 FTIPKEQYTIINR--TASSVTFTDIASLNIQLTCNILTFGQLEQNVYGI--TIISGL--- 124
++I K + + N SSV T N+ + F +N YG+ ++S +
Sbjct 28619 YSIEKRETSQTNWKMVCSSVARTTFKVPNL-VKDAEYQFRVRAENRYGVSQPLVSSIIVA 28677
Query 125 --------PPEKPKNLSCIVNEGKKMRCEWD-GGRETHLE-TNFTLKSEWATHKFADCKA 174
PP KP + M WD + E T F ++ +
Sbjct 28678 KHQFRIPGPPGKPVIYN---VTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVN 28734
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKP-NPPHNLSVIN 232
V ++ + V AEN+ G SD F V P +PP I+
Sbjct 28735 TSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLA--VSPVDPPGTPDYID 28792
Query 233 SEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ L W P I+ Y+I+ R + + T + +TV L P
Sbjct 28793 VTRE--TITLKWNPPLRDGGSKIVGYSIEKRQGNERW---VRCNFTDVSECQYTVTGLSP 28847
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA-----PSFWYKIDPSHTQGYRT 346
Y FRI G S S+ + I D P ++ + + R
Sbjct 28848 GDRYEFRIIARNAV--GTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRI 28905
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND-RYLATLTVRNL 405
LV + P E+ + + + + + T D R + T+ +N
Sbjct 28906 KALV-QGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTVEAKNA 28963
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAP 465
G + A + + + M + W P I + + +
Sbjct 28964 SGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT-LWWDAPLNDGCAPITHYIIEKRETS 29022
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP---ESIKAYLKQAPPSKG 522
+ ED ++Y L Y V+ V G G P + + A ++ P
Sbjct 29023 RLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAP 29082
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNV--DSSHTEYTL 579
+ N L W P I+ Y + R V S T + +
Sbjct 29083 GIPEPSNITGNSITLTW-ARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKV 29141
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLF 639
+ LT Y + A G GP + + + P + T+ V
Sbjct 29142 TGLTEGNEYEFHVMAENAAGV--GPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSL 29199
Query 640 CFNKRDL 646
++K
Sbjct 29200 EWSKPVF 29206
Score = 163 bits (411), Expect = 3e-39, Method: Composition-based stats.
Identities = 95/621 (15%), Positives = 197/621 (32%), Gaps = 38/621 (6%)
Query 32 SPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTF 91
++ VV+ ++ + + VW + + S++T
Sbjct 29290 FKQTHVVRAGASIRLFIAYQGR-------PTPTAVWSKPDSNLSLRADIHTTDSFSTLTV 29342
Query 92 TDIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
+ + + T + + + + ++ P P ++ WD
Sbjct 29343 ENCNRNDAGKYTLTVENNSGSKSITFTVKVL--DTPGPPGPITFKDVTRGSATLMWDAPL 29400
Query 151 ETHLET--NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
++ ++ A+ + +++ V V A N G
Sbjct 29401 LDGGARIHHYVVEKREASRRSWQVISEK-CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGE 29459
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDAS 267
+ V +P PP L V+++ + S++ L W P I Y ++ R K +
Sbjct 29460 PYEMPEPIVATEQPAPPRRLDVVDTSKSSAV--LAWLKPDHDGGSRITGYLLEMRQKGSD 29517
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
W E + + +FTV+ L TEY FR++ + G + + P+
Sbjct 29518 FW----VEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPT 29573
Query 328 KAPS-FWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK 386
+ ++ T+ + P + K+ + + T S
Sbjct 29574 ADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLT 29633
Query 387 LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
+ ++ D LT+ N G +V + +++ + ++ + + W P
Sbjct 29634 VKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCV-LSWGEP 29692
Query 447 RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPG 505
++ I + ++ + T WQ + +V RT ++ +L + Y V+ G
Sbjct 29693 KDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVS 29751
Query 506 SP---ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII 562
P I A PPS V N + W++ P I Y +
Sbjct 29752 KPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEE-PYHDGGSKIIGY---WVEKK 29807
Query 563 GNETAVNVDSS-----HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
T + V + Y ++ L Y R A G E + P AQ
Sbjct 29808 ERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEA--SRPIMAQNP 29865
Query 618 IEAIVVPVCLAFLLTTLLGVL 638
++A P +T+ +
Sbjct 29866 VDAPGRPEVTDVTRSTVSLIW 29886
Score = 162 bits (409), Expect = 5e-39, Method: Composition-based stats.
Identities = 100/597 (17%), Positives = 190/597 (32%), Gaps = 31/597 (5%)
Query 57 YFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVY 116
+ W N T+P+E +SS+ + + + ++L + +
Sbjct 17475 VSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVY-SLLAKNEAGERKK 17533
Query 117 GITIISGLPPEKPKNLSCIVNEGKKMRC--EW-DGGRETHLE-TNFTLKSEWATHKFADC 172
I + P P + + C W + TN+ ++ + +
Sbjct 17534 TIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTP 17592
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT---SDHINFDPVYKVKPNPPHNLS 229
T + TV + AEN++G + P P +L
Sbjct 17593 VTYTVTRQNATVQGLIQGKA-YFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE 17651
Query 230 VINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
V E + + LTW P I+ Y ++ R + ++ ++ S + +TV+
Sbjct 17652 VK--EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRK--YTVKG 17707
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
LK Y +R+ + G+G S ++ + P+ F K+ +
Sbjct 17708 LKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTI-RVGEAFALT 17766
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL-TNDRYLATLTVRNLVG 407
+ P + + + +V L ++H++ + +D + V N G
Sbjct 17767 GRYSGKPKPKVSWFKDEADV-LEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTG 17825
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
+ KD M+ + W P + I + + +
Sbjct 17826 SRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMV-ISWKPPLDDGGSKITNYIIEKKEVGKD 17884
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP---ESIKAYLKQAPPSKGPT 524
+ T L E K Y+ + G P +S+KA + P
Sbjct 17885 VWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQ 17944
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNVDSSH--TEYTLSS 581
+V K+ A++ W+ I NY + R + V D H T++ +
Sbjct 17945 PIVTEVTKDSALVTWN--KPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPD 18002
Query 582 LTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGV 637
L Y R++A + G G P P FA+ I PV + TT V
Sbjct 18003 LLEGCQYEFRVSAENEIGIGDPSPPSK---PVFAKDPIAKPSPPVNPEAIDTTCNSV 18056
Score = 161 bits (408), Expect = 7e-39, Method: Composition-based stats.
Identities = 98/563 (17%), Positives = 170/563 (30%), Gaps = 55/563 (10%)
Query 75 PKEQYTIINRTASSVTFTDIASLNIQLT---------CNILTFGQLEQNVYGITIISGLP 125
P + Y + R S + +T ++ +IQ N F N YG
Sbjct 21430 PIKSYILEKRETSRLLWTVVSE-DIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQ-- 21486
Query 126 PEKPKNL-------------SCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATH-KF 169
+P + W + T + ++ ++
Sbjct 21487 -SEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRW 21545
Query 170 ADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKV---KPNPPH 226
+ C V E V AEN G + + K P PP
Sbjct 21546 VRAIKTPVSDLRCKVTGLQEG-STYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPS 21604
Query 227 NLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
N V ++ + S+ L W P + I Y ++++ W + TA + F
Sbjct 21605 NPHVTDTTKKSAS--LAWGKPHYDGGLEITGYVVEHQKVGDEAWIK-DTTGTALRITQFV 21661
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK-APSFWYKIDPSHTQGY 344
V DL+ +Y FRI + + G G E A E + AP F + T
Sbjct 21662 VPDLQTKEKYNFRISAINDAGVG------EPAVIPDVEIVEREMAPDFELDAELRRTLVV 21715
Query 345 R---TVQLV--WKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT 399
R ++++ K P E + + + +++T+ D
Sbjct 21716 RAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPEC--NRYDTGKFV 21773
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
+T+ N GK + + + D + KD+ + + W P I + V
Sbjct 21774 MTIENPAGK-KSGFVNVRVLDTPGPVLNLRPTDITKDS-VTLHWDLPLIDGGSRITNYIV 21831
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-ESIKAYLKQAP 518
+A + TY L+E Y V G G P E+ +
Sbjct 21832 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 21891
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
PS ++ + K+ L W P I Y I + ++ E
Sbjct 21892 PSPPDSLNIMDITKSTVSLAW-PKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLECV 21950
Query 579 LSSLTSDTLYMVRMAAYTDEGGK 601
+ +LT Y ++ A G
Sbjct 21951 VRNLTEGEEYTFQVMAVNSAGRS 21973
Score = 161 bits (407), Expect = 9e-39, Method: Composition-based stats.
Identities = 91/567 (16%), Positives = 167/567 (29%), Gaps = 41/567 (7%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNV 115
I W + T S + + +N + +
Sbjct 30396 SVSGRPPPVITWSKQGIDLASRAII---DTTESYSLLIVDKVNRYDAGKYTIEAENQSGK 30452
Query 116 YGITIISGLPPEKPK---NLSCIVNEGKKMRCEWD-GGRETHLE-TNFTLKSEWATHKFA 170
T++ + P ++ + W+ + N+ ++ A +
Sbjct 30453 KSATVLV-KVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAF 30511
Query 171 DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
+ + T + + V EN G + + P P L V
Sbjct 30512 KTVTTKCSKTLYRISGLVEGTMYY-FRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEV 30570
Query 231 INSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
++ S + L W P + Y ++ W ++ T TV L
Sbjct 30571 VDV--TKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVT--LKPTVLEHTVTSL 30626
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS---HTQGYRT 346
+Y+FRIR E G S+ E + +T +D P+ P H R
Sbjct 30627 NEGEQYLFRIRAQNEKGV---SEPRETVTAVTVQDL-RVLPTIDLSTMPQKTIHVPAGRP 30682
Query 347 VQLVW--KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRN 404
V+LV PP A+ ++ + + + V + D TL ++N
Sbjct 30683 VELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKN 30742
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES----VKKYILEWCVL 460
+ G + + I + + + + W P + Y++E
Sbjct 30743 VTGTTSETIKVIILDKPGPPTGPIKIDEIDA-TSITISWEPPELDGGAPLSGYVVE---- 30797
Query 461 SDKAPCITDWQQEDGTVHR-TYLRGNLAESKCYLITVTPVYADGPGS---PESIKAYLKQ 516
+ W +V R T+ L E Y+ V G GS E I+
Sbjct 30798 -QRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSI 30856
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSH 574
P T++ V ++ L W P D + Y + + + + V +
Sbjct 30857 RIPGPPETLQIFDVSRDGMTLTWYP-PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTM 30915
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGK 601
T Y + LT Y R+ A G
Sbjct 30916 TRYRSTGLTEGLEYEHRVTAINARGSG 30942
Score = 159 bits (402), Expect = 3e-38, Method: Composition-based stats.
Identities = 110/625 (18%), Positives = 194/625 (31%), Gaps = 68/625 (11%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTAS-SVTFTDIASLNIQLTCNILTFGQLEQN 114
I W + +P +Q T IN T S +T I + G N
Sbjct 24179 PISGRPKPTITWTKDG--LPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY---GITVAN 24233
Query 115 VYG--------ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEW 164
V G +T+ PP+ P + + + W+ T TN+ ++
Sbjct 24234 VVGQKTASIEIVTLDKPDPPKGP--VKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRD 24291
Query 165 ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV---TSDHINFDPVYKVK 221
T D + T+ V + + AEN G+ SD I YK +
Sbjct 24292 TTTTVWDVVSATVARTTLKVTKLKTG-TEYQFRIFAENRYGQSFALESDPIVAQYPYK-E 24349
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTAST 280
P PP + S +++ W P ++ Y+++ + +++ W+++ T
Sbjct 24350 PGPPGTPFATAISKDSMVIQ--WHEPVNNGGSPVIGYHLERKERNSILWTKVN--KTIIH 24405
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
+ F Q+L+ EY FR+ G G S SE D P K +
Sbjct 24406 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRN--- 24462
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLT-----RWKSHLQNYTVNATKLTVNLTND- 394
+ L W T P ++ I Y V RW + LT D
Sbjct 24463 -----EITLQW-TKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQ 24516
Query 395 RYLATLTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW-----------V 441
RY + +N G + + P + + +D ++ V
Sbjct 24517 RYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADV 24576
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
+++ + + A C + + D + Y++ + V
Sbjct 24577 HGKPLP--TIEWLRGDKEIEESARC--EIKNTDFKALLIVKDAIRIDGGQYILRASNVAG 24632
Query 502 DGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI 561
P ++K + PP V+ V + L W P+ I +Y + R
Sbjct 24633 -SKSFPVNVKVLDRPGPPEGP--VQVTGVTSEKCSLTWSP-PLQDGGSDISHYVVEKRET 24688
Query 562 IG-NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
T V + ++ L Y+ R+ A G + E P +
Sbjct 24689 SRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESA---PVLMKNPFVL 24745
Query 621 IVVPVCLAFLLTTLLGVLFCFNKRD 645
P L + C+N+ D
Sbjct 24746 PGPPKSLEVTNIAKDSMTVCWNRPD 24770
Score = 159 bits (402), Expect = 3e-38, Method: Composition-based stats.
Identities = 107/606 (18%), Positives = 190/606 (31%), Gaps = 58/606 (10%)
Query 78 QYTIINRTASSVTFTDIASLNIQL--------TCNILTFGQLEQNVYGI-------TIIS 122
Y ++ R S+ +T++++ + T F +N +GI +
Sbjct 27531 NYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTV 27590
Query 123 GLP---PEKPKNLSCIVNEGKKMRCEWD-GGRETHLETN-FTLKSEWATHKFADCKAKRD 177
LP P P + + W + L+ + K
Sbjct 27591 KLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLV 27650
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
T+ + + E V AENA G H + + PP N+ + + + S
Sbjct 27651 IRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNS 27710
Query 238 SILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
+ L+W P+ I Y ++ R W+ T T + F + L ++Y
Sbjct 27711 --VSLSWQQPAFDGGSKITGYIVERRDLPDGRWT--KASFTNVTETQFIISGLTQNSQYE 27766
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ-------L 349
FR+ G S+ SE IT D P ++ + YR +
Sbjct 27767 FRVFARNAV--GSISNPSEVVGPITCIDS-YGGPVIDLPLEYTEVVKYRAGTSVKLRAGI 27823
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND-----RYLATLTVRN 404
K P E Y+ +++ N T L L D L +RN
Sbjct 27824 SGKPAPTIEW------YK-DDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRN 27876
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
+G + A + ++ K + + + W P + I + ++ +
Sbjct 27877 AMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLL-WRPPADDGGAKITHY-IVEKRE 27934
Query 465 PCITDWQQEDGTVHRTYLRGN-LAESKCYLITVTPVYADGPGSP-ESIKAYLKQAPPSKG 522
W + + + + Y+ V V G G P ES K A + G
Sbjct 27935 TSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPG 27994
Query 523 PT--VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAV-NVDSSHTEYT 578
P K+ KN + W + P+ I Y + R V T
Sbjct 27995 PPGIPEVTKITKNSMTVVWSR-PIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQK 28053
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
++ LT ++ Y R+ A G GP + A I+ P + +T +
Sbjct 28054 VTGLTENSDYQYRVCAVNAAG--QGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSIT 28111
Query 639 FCFNKR 644
++K
Sbjct 28112 LGWSKP 28117
Score = 159 bits (401), Expect = 4e-38, Method: Composition-based stats.
Identities = 83/543 (15%), Positives = 160/543 (29%), Gaps = 62/543 (11%)
Query 106 LTFGQLEQNVYGIT-------IISGLP---PEKPKNLSCIVNEGKKMRCEWDGGRE--TH 153
F N YGI+ ++ P P P + M W +
Sbjct 16496 YEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGS 16555
Query 154 LETNFTLKSEWATHKFAD----CKAKRDTPTSCTVDYSTVYF-VNIEVWVEAENALG--- 205
T + L+ + + + + V + A NA G
Sbjct 16556 PITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGP 16615
Query 206 -KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYRT 263
SD P PP V + S + L W P+ I Y ++ +
Sbjct 16616 PSEPSDP-EVAGDPIFPPGPPSCPEVKDK--TKSSISLGWKPPAKDGGSPIKGYIVEMQE 16672
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+ + W ++ D T V +LK +Y FR++ + E G+ SD + E +
Sbjct 16673 EGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQ 16732
Query 324 DRPSKAPSF---WYKIDPSHTQGYRTVQLVWKTLPPFEAN--GKILDYEVTLTRWKSHLQ 378
+ P + + +Q + + P GK K +
Sbjct 16733 EEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGK------AKKAMKDGVH 16786
Query 379 NYT--------VNATKLTVNLTNDRY--LATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+ N++ + + + ++T +N G A + D +
Sbjct 16787 DIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAG-QKTANCRVKVMDVPGPPKDL 16845
Query 429 DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR-TYLRGNLA 487
+ + + + W P + I + + W + + T++ +L
Sbjct 16846 KVSDITRGSCR-LSWKMPDDDGGDRIKGYVIEKRTIDG-KAWTKVNPDCGSTTFVVPDLL 16903
Query 488 ESKCYLITVTPVYADGPGSP-ESIKAYLKQ---APPSKGPTVRTKKVGKNEAVLEWDQLP 543
+ Y V G G P E+I+ + PP ++ + KN L W P
Sbjct 16904 SEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKP-P 16962
Query 544 VDVQNGFIRNYTIF---YRTIIGNE----TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
+ + +Y + + + D ++T+ L Y R+ A
Sbjct 16963 KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVN 17022
Query 597 DEG 599
G
Sbjct 17023 AAG 17025
Score = 158 bits (398), Expect = 1e-37, Method: Composition-based stats.
Identities = 98/602 (16%), Positives = 170/602 (28%), Gaps = 48/602 (8%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNI-QLTCNILTFGQLEQN 114
A + W ++ + + + + + + + I +
Sbjct 21726 PIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSG 21785
Query 115 VYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADC 172
+ ++ P NL + WD TN+ ++ AT K
Sbjct 21786 FVNVRVL--DTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSY-S 21842
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
A V AEN G P+PP +L++++
Sbjct 21843 TATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMD 21902
Query 233 SEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
S + L W P I Y I+ + K + W+ I T V++L
Sbjct 21903 I--TKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI----TTVKGLECVVRNLTE 21956
Query 292 FTEYVFRIRCMKEDGKGYW--SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
EY F++ + G+ S + + I + + +
Sbjct 21957 GEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPV 22016
Query 350 VWKTLPPFEANGKILDYEVTLTRW-----KSHLQNYTVNATKLTVNL----TNDRYLATL 400
+ + P VT + ++ N+ AT +N+ +D L
Sbjct 22017 LGRPKP-----------TVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL 22065
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
T RN+VG+ V+TI D + + W P I + V
Sbjct 22066 TARNIVGE-VGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 22124
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS---PESIKAYLKQA 517
+ T + + TY L Y V G G I A
Sbjct 22125 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFK 22184
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG----NETAVNVDSS 573
P T + V K+ + W P+ I Y + + G + V +
Sbjct 22185 VPGPPGTPQVTAVTKDSMTISW-HEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGN 22243
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTT 633
+ S LT Y R+ A G + + P A I+ PV L T
Sbjct 22244 I--FKSSGLTDGIAYEFRVIAENMAGKSKPSKP--SEPMLALDPIDPPGKPVPLNITRHT 22299
Query 634 LL 635
+
Sbjct 22300 VT 22301
Score = 156 bits (395), Expect = 3e-37, Method: Composition-based stats.
Identities = 82/497 (16%), Positives = 153/497 (31%), Gaps = 39/497 (8%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCT 183
P P N + C+W+ + N+TL+ + T ++ T C
Sbjct 15729 PGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCK 15788
Query 184 VDYSTVYF-VNIEVWVEAENALGKVT---SDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ + V AEN G S + + P+ P V + S +
Sbjct 15789 YSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPF-GPPDAPDKPIVEDVTSNSML 15847
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+K W P IL Y ++ R +++ WS++ + + V L YVFR+
Sbjct 15848 VK--WNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALK--ANVDGLLEGLTYVFRV 15903
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
G G +S S+ + I T++L W+ P F
Sbjct 15904 CAENAAGPGKFSPPSDPKTAH------DPISPPGPPIPRVTDTSSTTIELEWEP-PAFNG 15956
Query 360 NGKILDY----EVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAAV 413
G+I+ Y ++ T S + + TV Y ++ N G+
Sbjct 15957 GGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGE 16016
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR-------ESVKKYILEWCVLSDKAPC 466
P ++L K + + T R V + W +
Sbjct 16017 TQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV--WTKEEGELDK 16074
Query 467 ITDWQQEDGTVHRTYLRGNL-AESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
GT ++ L + Y+IT T + ++ + P +
Sbjct 16075 DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAAR-VEVF---DVPGPVLDL 16130
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
+ + +L W P D I + I + + +++ ++ ++ L
Sbjct 16131 KPVVTNRKMCLLNWSD-PEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEG 16189
Query 586 TLYMVRMAAYTDEGGKD 602
Y R+ A G
Sbjct 16190 QEYKFRVIAKNKFGCGP 16206
Score = 155 bits (392), Expect = 5e-37, Method: Composition-based stats.
Identities = 104/601 (17%), Positives = 186/601 (31%), Gaps = 67/601 (11%)
Query 66 VWKTNHFTIPKEQYTIIN-RTASSVTFTDI---ASLNIQLTCNILTFGQLEQNVYGITII 121
VW + K++ I N T S + D +T + +
Sbjct 16064 VWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAA----ARVE 16119
Query 122 SGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTP 179
P +L +V K W + T F ++ + A + +
Sbjct 16120 VFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERS 16179
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP-NPPHNL-SVINSEELS 237
C + + V A+N G + P+ V P PP + + +E
Sbjct 16180 K-CDITGLLEG-QEYKFRVIAKNKFGCGP--PVEIGPILAVDPLGPPTSPERLTYTERTK 16235
Query 238 SILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
S + L W P S I Y I+ R D + ++ +SF V++L Y
Sbjct 16236 STITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLC--PTTSFLVENLDEHQMYE 16293
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID--------------PSHTQ 342
FR++ + E G+ S+ S + + +D + P+
Sbjct 16294 FRVKAVNEIGE---SEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVT 16350
Query 343 GYRTVQLVWKT-----LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL 397
G ++ W P +A +I EV+ + K+ L + + D+
Sbjct 16351 GLPMPKIEWSKNETVIEKPTDAL-QITKEEVSRSEAKTELS--------IPKAVREDKGT 16401
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
T+T N +G S + + D + + + ++ ++ W P ++ I +
Sbjct 16402 YTVTASNRLG-SVFRNVHVEVYDRPSPPRNLAVTDIKAESC-YLTWDAPLDNGGSEITHY 16459
Query 458 CVLSDKAPCIT-DWQQEDGT-VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
+ A +W++ T V + Y L + Y V V G +
Sbjct 16460 VIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVI 16519
Query 516 QAP---PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS 572
Q P P + K ++ W P+D I Y + R + +
Sbjct 16520 QDPYRLPGPPGKPKVLARTKGSMLVSWTP-PLDNGGSPITGYWLEKREEGSPYWSRVSRA 16578
Query 573 SHTEYTLSS-------LTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPV 625
T+ L L Y R A G GP + P+ A I P
Sbjct 16579 PITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGI--GPPSEPSDPEVAGDPIFPPGPPS 16636
Query 626 C 626
C
Sbjct 16637 C 16637
Score = 155 bits (392), Expect = 5e-37, Method: Composition-based stats.
Identities = 108/636 (17%), Positives = 188/636 (30%), Gaps = 60/636 (9%)
Query 36 PVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIA 95
V++ + +K + I W + +E+ + + V
Sbjct 18845 ITVRVGQTIRILARVKGR-------PEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKE 18897
Query 96 SLNIQLTCNILTFGQLEQNVYG-ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHL 154
++ I++ + G + P +NL + W+ +
Sbjct 18898 AVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGG 18957
Query 155 E--TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS--- 209
TNF ++ K A T + V AEN +G +
Sbjct 18958 SEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLA--NNEYYFRVCAENKVGVGPTIET 19015
Query 210 --DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDA 266
+ +P+ + P P NL + + + + L W P L Y+++ R K +
Sbjct 19016 KTPILAINPIDR--PGEPENLHIADKG--KTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 19071
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
W ++ + + + V Y FR++ E G+ SDW + + ED
Sbjct 19072 DDWERV--HKGSIKETHYMVDRCVENQIYEFRVQTKNEGGE---SDWVKTEEVVVKEDLQ 19126
Query 327 SKAPSFWYKIDPSHTQGYRTVQL----VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
+ T++L K P ++T +
Sbjct 19127 KPVLDLKLSG-VLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADS 19185
Query 383 NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWV 441
+ LT +D +T N G A PV +LK + V
Sbjct 19186 SKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLD---KPGPVRNLKIVDVSSDRCTV 19242
Query 442 EWTTPRES----VKKYILEWCVLSDKAPCITDWQQEDGTV-HRTYLRGNLAESKCYLITV 496
W P + ++ YILE C W TV L E Y+ V
Sbjct 19243 CWDPPEDDGGCEIQNYILEKC-----ETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRV 19297
Query 497 TPVYADGPGSP---ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
G G P + + A K P + KV K E + W+ D I
Sbjct 19298 RAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKS-ITG 19356
Query 554 YTIFYRTIIGNETAVNVDSS-----HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
Y + + V + + +L D Y R+ A + G + P
Sbjct 19357 YFL---EKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGE-PSLP- 19411
Query 609 TTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
+ P A+ IE P + TT + + K
Sbjct 19412 SRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKP 19447
Score = 154 bits (389), Expect = 1e-36, Method: Composition-based stats.
Identities = 98/514 (19%), Positives = 167/514 (32%), Gaps = 63/514 (12%)
Query 122 SGLP--PEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTL-KSEWATHKFADCKAKR 176
G P P P + + M +W ++ TN+ L K + +K+ C +
Sbjct 21000 VGKPGIPTGP--IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV 21057
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGK---VTSDHINFDPVYKVKPNPPHNLSVINS 233
T V AEN G + S+ I + V PP
Sbjct 21058 QKTTFRVTRLHEGM--EYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPP---NIV 21112
Query 234 EELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
+ + LTWT+P I Y+++++ +++ W + T F V L
Sbjct 21113 DVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKR--ANKTPIRMRDFKVTGLTEG 21170
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
EY FR+ + G G S SE + D P K + +V L+W
Sbjct 21171 LEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRN--------SVTLIW- 21221
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQ------NYTVNATKLTVNLTNDRYLATLTVRNLV 406
T P ++ K+ Y V S N A +T + +Y + +N
Sbjct 21222 TEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTA 21281
Query 407 GK----SDAAVLTIPACDFQATHPVMDLK----------AFPKDNMLWVEWTTPRESVKK 452
G S++ I +++A V+D N + + +S
Sbjct 21282 GAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSS-- 21339
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLR---GNLAESKCYLITVTPVYADGPGSPES 509
+ K +D Q T + L ++ Y IT T + E
Sbjct 21340 -----WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKV---EH 21391
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAV 568
+K + P V V +A L W P++ I++Y + R T V
Sbjct 21392 VKVTVL-DVPGPPGPVEISNVSAEKATLTWTP-PLEDGGSPIKSYILEKRETSRLLWTVV 21449
Query 569 NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ D + + L Y+ R++A G +
Sbjct 21450 SEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGE 21483
Score = 154 bits (388), Expect = 1e-36, Method: Composition-based stats.
Identities = 110/637 (17%), Positives = 190/637 (30%), Gaps = 94/637 (15%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTII--NRTASSVT 90
E VV+ + +++ V W T+ I +++ + + +S +T
Sbjct 18444 IEGLVVKAGTTVRFPAIIR-------GVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLT 18496
Query 91 FTD-----IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCE 145
+ I ++ N + ++ + PP P N+ + + M
Sbjct 18497 IKNCLRRDTGEYQITVS-NAAGSKTVAVHL--TVLDVPGPPTGPINI--LDVTPEHMTIS 18551
Query 146 WDGGRETHLET--NF------TLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
W ++ N+ T K W K K P
Sbjct 18552 WQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPH-------LQKGCEYVFR 18604
Query 198 VEAENALGKVTSDHINFDPVYKV------KPNPPHNLSVINSEELSSILKLTWTNP-SIK 250
V AEN +G D V P+PP V + E ++ ++WT P S
Sbjct 18605 VRAENKIGVGPP----LDSTPTVAKHKFSPPSPPGKPVVTDITENAA--TVSWTLPKSDG 18658
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
I Y ++ R W ++ A + F V L Y FR+ G
Sbjct 18659 GSPITGYYMERREVTGK-WVRVNKTPIADLK--FRVTGLYEGNTYEFRVFAENLAGLSKP 18715
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVT 369
S S+ P I+P R T LVW T P + IL Y V
Sbjct 18716 SPSSDPIKACRPIKPPGPP------INPKLKDKSRETADLVW-TKPLSDGGSPILGYVVE 18768
Query 370 LT-RWKSHLQNYTVN------ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
+ + A ++ + + Y + N+VG+ + L
Sbjct 18769 CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKD 18828
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
HP +++ V V + I + + W +E + R
Sbjct 18829 ILHPPEVELDVTCRDVITVR-------VGQTIRILARVKGRPEPDITWTKEGKVLVREKR 18881
Query 483 RGNLAE---------------SKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
+ + Y+I+ GS I L + P ++
Sbjct 18882 VDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSA--IVNVLDR--PGPCQNLKV 18937
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTL 587
V K + W+ P+D I N+ + YR ++ ++L ++
Sbjct 18938 TNVTKENCTISWEN-PLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNE 18996
Query 588 YMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVP 624
Y R+ A G GP TP A I+ P
Sbjct 18997 YYFRVCAENKVGV--GPTIETKTPILAINPIDRPGEP 19031
Score = 153 bits (385), Expect = 4e-36, Method: Composition-based stats.
Identities = 94/599 (16%), Positives = 181/599 (30%), Gaps = 62/599 (10%)
Query 34 ESPVVQLHSNFTAVCVLKEKCM-----DYFHVNANYIVWKTNHFTIPKEQYTIINRTASS 88
E P+ + S ++K + ++W + Y + +S
Sbjct 27109 EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTS 27168
Query 89 VTFTDIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD 147
+T + + + T I + ++ P P N++ + WD
Sbjct 27169 LTIENANRNDSGKYTLTIQNVLSAASLTLVVKVL--DTPGPPTNITVQDVTKESAVLSWD 27226
Query 148 -GGRETHLET-NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
+ N+ ++ A+ K + V EN G
Sbjct 27227 VPENDGGAPVKNYHIEKREASKKAWVSVTNN-CNRLSYKVTNLQEGAIYYFRVSGENEFG 27285
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYRTK 264
KP+PP L V + + LTW P I+ Y ++ K
Sbjct 27286 VGIPAETKEGVKITEKPSPPEKLGVTSI--SKDSVSLTWLKPEHDGGSRIVHYVVEALEK 27343
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
W + + + V L+ +EY FR+ + G SD E +
Sbjct 27344 GQKNW----VKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGL---SDPRELLLPV-LIK 27395
Query 325 RPSKAPSFWYKIDPSHTQGYRT-------VQLVWKTLPPFEANGKILDYEVTLTRWKSHL 377
+ P K PSHT R + + K LP VTL+R L
Sbjct 27396 EQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPK-----------VTLSRDGVPL 27444
Query 378 QNYTVNATKLTVN---------LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+ T++T +T D +T N G + A + + +
Sbjct 27445 KATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPV 27504
Query 429 DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG-NLA 487
+ +++ + ++W P+ + + +L + W + TV RT ++ L
Sbjct 27505 VISDITEES-VTLKWEPPKYDGGSQVTNY-ILLKRETSTAVWTEVSATVARTMMKVMKLT 27562
Query 488 ESKCYLITVTPVYADGPG---SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
+ Y + G + L P T V + + W PV
Sbjct 27563 TGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGW-HEPV 27621
Query 545 DVQNGFIRNYTIFYRTII----GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ Y + + + + ++H + T ++++ +Y R+ A G
Sbjct 27622 SNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVT--TISAGLIYEFRVYAENAAG 27678
Score = 153 bits (385), Expect = 4e-36, Method: Composition-based stats.
Identities = 96/614 (16%), Positives = 175/614 (29%), Gaps = 59/614 (10%)
Query 69 TNHFTIPKEQYTIINR--TASSVTFTDIASLNIQLTCNILTFGQLEQNVYGI-------- 118
+ + + + + SVT + + N F N +GI
Sbjct 30791 LSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLT-EGNEYVFRVAATNRFGIGSYLQSEV 30849
Query 119 --TIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKA 174
S P P+ L M W + T + ++ +
Sbjct 30850 IECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVN 30909
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV----TSDHINFDPVYKVKPNPPHNLSV 230
K + + E V A NA G S I P P N V
Sbjct 30910 KVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPI-VAMDPIAPPGKPQNPRV 30968
Query 231 INSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
++ S + L W+ P + + Y I+ + D W++ T + +T+ L
Sbjct 30969 TDTTRTS--VSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNT--TPTKIREYTLTHL 31024
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK-IDPSHTQGYRTVQ 348
EY FR+ G G ++ + P Y+ G +
Sbjct 31025 PQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLT 31084
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT--------VNATKLTVNL--TNDRYLA 398
+ I + +W Q+ + T+L + D
Sbjct 31085 I------------PIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTY 31132
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWC 458
L + N GK + + ++ + + V W P + IL +
Sbjct 31133 DLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRS-VRVSWRPPADDGGADILGYI 31191
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-ESIKAYLKQA 517
+ + P + + + + L E+ Y V+ G P +S + +
Sbjct 31192 LERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKT 31251
Query 518 ----PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVD 571
P V K+ L W + P D + Y I + ++
Sbjct 31252 PLNPPEPPSNPPEVLDVTKSSVSLSWSR-PKDDGGSRVTGYYIERKETSTDKWVRHNKTQ 31310
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLL 631
+ T YT++ L D Y R+ A D G + + P + + P L L
Sbjct 31311 ITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPA--SEPVVCKDPFDKPSQPGELEILS 31368
Query 632 TTLLGVLFCFNKRD 645
+ V + K +
Sbjct 31369 ISKDSVTLQWEKPE 31382
Score = 152 bits (383), Expect = 7e-36, Method: Composition-based stats.
Identities = 102/578 (18%), Positives = 170/578 (29%), Gaps = 67/578 (12%)
Query 59 HVNANYIVWKTNHF--TIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVY 116
A + W+ + K Q +++ A V + + + ++ +
Sbjct 19559 GRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV 19618
Query 117 GITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKA 174
+ ++ P +L W T++ ++ A K
Sbjct 19619 NVRVL--DTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVT 19676
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK---PNPPHNLSVI 231
TS V V A N G + + P+PP L V
Sbjct 19677 PEVKKTSFHVTNLVPGNEYY-FRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEV- 19734
Query 232 NSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+E + L W P I Y YR ++ E + S V LK
Sbjct 19735 -TEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPA--DRWTEYSVVKDLSLVVTGLK 19791
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
+Y FR+ G EA G+ YE + P + + + +++
Sbjct 19792 EGKKYKFRVAARNAVGVSLP----REAEGV-YEAKEQLLPPKILMPEQITIKAGKKLRI- 19845
Query 351 WKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN-------------LTNDRYL 397
GK +WK ++ V ++ L V+ D
Sbjct 19846 -----EAHVYGKPH----PTCKWKKG-EDEVVTSSHLAVHKADSSSILIIKDVTRKDSGY 19895
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES----VKKY 453
+LT N G + + P D+ D + W P E + Y
Sbjct 19896 YSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADAC-SLSWHIPLEDGGSNITNY 19954
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVYADGPGSP---ES 509
I+E C +S DW +V +T G L + Y+ V G P
Sbjct 19955 IVEKCDVSRG-----DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPK 20009
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
+ A PS+ R KV K+ + WD+ P I Y I + + +
Sbjct 20010 MVAQFPFGVPSEPKNARVTKVNKDCIFVAWDR-PDSDGGSPIIGYLIERKE---RNSLLW 20065
Query 570 VDSSH-----TEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
V ++ TEY + L Y R+ A G
Sbjct 20066 VKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSP 20103
Score = 151 bits (382), Expect = 8e-36, Method: Composition-based stats.
Identities = 83/500 (17%), Positives = 159/500 (32%), Gaps = 44/500 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCT 183
PP+ P M +W+ ++ + L+ K
Sbjct 15829 PPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKA 15888
Query 184 VDYSTVYFVNIEVWVEAENALG----KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ + V AENA G SD P ++ + S+
Sbjct 15889 NVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVT----DTSSTT 15944
Query 240 LKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
++L W P+ I+ Y + + + WS+ + +TV++++ +Y R
Sbjct 15945 IELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKV--RQYTVKEIREGADYKLR 16002
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ---GYRTVQLVWKTLP 355
+ + G+G + + P + P+ + +T+++
Sbjct 16003 VSAVNAAGEGPPGE-----TQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRI------ 16051
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNA-----TKLTVN--LTNDRYLATLTVRNLVGK 408
P G+ + +V ++ V ++L + L D +T N G
Sbjct 16052 PAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCG- 16110
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNML-WVEWTTPRESVKKYILEWCVLSDKAPCI 467
S A + D PV+DLK + + + W+ P + I ++ K +
Sbjct 16111 SKFAAARVEVFDVPG--PVLDLKPVVTNRKMCLLNWSDPEDDGGSEITG-FIIERKDAKM 16167
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE---SIKAYLKQAPPSKGPT 524
W+Q T L E + Y V G G P I A PP+
Sbjct 16168 HTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPER 16227
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS--SHTEYTLSSL 582
+ + K+ L+W + P I+ Y I R + T + + +L
Sbjct 16228 LTYTERTKSTITLDWKE-PRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENL 16286
Query 583 TSDTLYMVRMAAYTDEGGKD 602
+Y R+ A + G +
Sbjct 16287 DEHQMYEFRVKAVNEIGESE 16306
Score = 151 bits (381), Expect = 1e-35, Method: Composition-based stats.
Identities = 108/635 (17%), Positives = 186/635 (29%), Gaps = 50/635 (8%)
Query 35 SPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDI 94
P ++ A + + W I T I T +S T
Sbjct 21308 DPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIK 21367
Query 95 ASLNI---QLTCNILT-FGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
+ + T FG ++V + PP P +S + E + W
Sbjct 21368 YATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPG-PVEISNVSAEKATL--TWTPPL 21424
Query 151 ETHLET--NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
E ++ L+ + T + D + V + V A N GK
Sbjct 21425 EDGGSPIKSYILE-KRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGE 21483
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDAS 267
+ P S + ++W P I Y+++ R K +
Sbjct 21484 PVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSL 21543
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
W + T + V L+ + Y FR+ G G S+ S+ P
Sbjct 21544 RW--VRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDA-AYPP 21600
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKL 387
PS + D + ++ L W P ++ +I Y V + T L
Sbjct 21601 GPPSNPHVTDTT----KKSASLAW-GKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTAL 21655
Query 388 TV-------NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW 440
+ T ++Y ++ N G + AV+ + P +L A
Sbjct 21656 RITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAE------- 21708
Query 441 VEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY 500
+ T + + + AP +T W +++ + N +I Y
Sbjct 21709 LRRTLVVRAGLSIRIFVPIKGRPAPEVT-WTKDNINLKNRANIENTESFTLLIIPECNRY 21767
Query 501 ADG------PGSPESIKAYLKQAP---PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
G ++ P +R + K+ L WD LP+ I
Sbjct 21768 DTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWD-LPLIDGGSRI 21826
Query 552 RNYTIFYRTIIGNETAVNVDSSHT-EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
NY + R + H Y ++ L+ Y R+ A + G + E T
Sbjct 21827 TNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETT--E 21884
Query 611 PKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRD 645
P A EA P L + T V + K
Sbjct 21885 PVKAS---EAPSPPDSLNIMDITKSTVSLAWPKPK 21916
Score = 150 bits (378), Expect = 3e-35, Method: Composition-based stats.
Identities = 102/617 (17%), Positives = 192/617 (31%), Gaps = 54/617 (9%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT-------DIASLNIQLTCNILTF 108
+ + W ++ + + T ++ T D+ ++LT +
Sbjct 23097 PFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSA--- 23153
Query 109 GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH---LETNFTLKSEWA 165
G+ + + I + PP P + + + + W + + K + +
Sbjct 23154 GEAIETLNVIVLDKPGPPTGPVKMDEVTAD--SITLSWGPPKYDGGSSINNYIVEKRDTS 23211
Query 166 THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT---SDHINFDPVYKVKP 222
T + A T T + + AEN GK T S+ +KV P
Sbjct 23212 TTTWQIVSATVARTTIKACRLKTG--CEYQFRIAAENRYGKSTYLNSEPTVAQYPFKV-P 23268
Query 223 NPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
PP V S S +++ W P S ++ Y+++ + +++ W + T +
Sbjct 23269 GPPGTPVVTLSSRDS--MEVQWNEPISDGGSRVIGYHLERKERNSILW--VKLNKTPIPQ 23324
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+ F L+ EY FR+ G G S SE D P + + +
Sbjct 23325 TKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRN---- 23380
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEV-----TLTRW-KSHLQNYTVNATKLTVNLTNDR 395
+V L WK P ++ KI Y V RW K+ N ++T + + R
Sbjct 23381 ----SVTLQWKK-PTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHR 23435
Query 396 YLATLTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKY 453
Y + RN G + + P + + KD ++ + + Y
Sbjct 23436 YEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIY 23495
Query 454 -----ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE 508
++W + + + + + + G S
Sbjct 23496 GKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVT 23555
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETA 567
L + P +GP V V + L W P+ I NY + R T
Sbjct 23556 VNVKVLDRPGPPEGP-VVISGVTAEKCTLAWKP-PLQDGGSDIINYIVERRETSRLVWTV 23613
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
V+ + ++ L Y R+ A G + E P A+ P
Sbjct 23614 VDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESE---PVVAKNPFVVPDAPKAP 23670
Query 628 AFLLTTLLGVLFCFNKR 644
T ++ + +
Sbjct 23671 EVTTVTKDSMIVVWERP 23687
Score = 148 bits (373), Expect = 1e-34, Method: Composition-based stats.
Identities = 101/610 (17%), Positives = 172/610 (28%), Gaps = 74/610 (12%)
Query 39 QLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASL- 97
+ + F A + E C + + ++ I K + T + T T +
Sbjct 17545 PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATV 17604
Query 98 NIQLTCNILTFGQLEQNVYGITIISGL-----------PPEKPKNLSCIVNEGKKMRCEW 146
+ F +N G+ PE+P++L + W
Sbjct 17605 QGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTW 17664
Query 147 DGGRETHLE--TNFTLKSEW-ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENA 203
+ + N+ L+S T KF TV E V A N
Sbjct 17665 NPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGD-TYEYRVSAVNI 17723
Query 204 LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY-- 261
+G+ K + PP L + ++L+ + +Y
Sbjct 17724 VGQGKPSFCTKPITCKDELAPPT-LHLDFRDKLTIRV-----------GEAFALTGRYSG 17771
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+ K +W + + R+ P T + +I+ + D G + E ++G
Sbjct 17772 KPKPKVSWFKDEADVLEDDRTHIKTT---PATLALEKIKAKRSDS-GKYCVVVENSTGSR 17827
Query 322 Y-------EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR-- 372
DRP + + + + WK P + KI +Y +
Sbjct 17828 KGFCQVNVVDRPGPPVGPVSFDEVTKD----YMVISWKP-PLDDGGSKITNYIIEKKEVG 17882
Query 373 ---WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA---AVLTIPACDFQATHP 426
W K++ L Y+ + NL G SD + P
Sbjct 17883 KDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAP 17942
Query 427 VMDLKAFPKDNMLWVEWTTPR---ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
+ + V W P + + YILE + W + Y +
Sbjct 17943 DQPIVTEVTKDSALVTWNKPHDGGKPITNYILE-----KRETMSKRWARVTKDPIHPYTK 17997
Query 484 G---NLAESKCYLITVTPVYADGPGSPES----IKAYLKQAPPSKGPTVRTKKVGKNEAV 536
+L E Y V+ G G P + A A PS N
Sbjct 17998 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 18057
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTLSSLTSDTLYMVRM 592
L W P I Y + Y+ + E T+Y ++ L Y R+
Sbjct 18058 LTWQP-PRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRV 18116
Query 593 AAYTDEGGKD 602
A G D
Sbjct 18117 LAVNAAGESD 18126
Score = 147 bits (370), Expect = 2e-34, Method: Composition-based stats.
Identities = 107/635 (17%), Positives = 193/635 (30%), Gaps = 66/635 (10%)
Query 30 YISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINR--TAS 87
I PV V E C+ + + + ++ + K + S
Sbjct 29664 VIGRPGPVT---GPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNS 29720
Query 88 SVTFTDIASLNIQLTCNILTFGQLEQNVYGI--TIISG--------LPPEKPKNLSCIVN 137
SV T I ++ +F +N +G+ + S +PP P
Sbjct 29721 SVKRTQIKVTHLTKY-MEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHV 29779
Query 138 EGKKMRCEWDGGRETHLETNFTLKSEWATHKFADC-----KAKRDTPTSCTVDYSTVYFV 192
M W+ E + + + W K + + K V +
Sbjct 29780 SANAMSIRWE---EPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGL 29836
Query 193 NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKS 251
+ A NA G + + + + + P V + S + L W+ P+
Sbjct 29837 EYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTR--STVSLIWSAPAYDGG 29894
Query 252 VIILKYNIQYRTKDASTWSQ-IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG-KGY 309
++ Y I+ + + + T + + FTV L Y FR+ G
Sbjct 29895 SKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISK 29954
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL------------VWKTLPPF 357
S+ + + P D + + L +W
Sbjct 29955 GSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKE 30014
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
+ +V+L + +D TLTV+N G +V+ +
Sbjct 30015 LDLCE----KVSLQYTGK------RATAVIKFCDRSDSGKYTLTVKNASGTKAVSVM-VK 30063
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
D + + ++ + W+ P+E I + ++ + +W +G
Sbjct 30064 VLDSPGPCGKLTVSRVTQEKCT-LAWSLPQEDGGAEITHY-IVERRETSRLNWVIVEGEC 30121
Query 478 -HRTYLRGNLAESKCYLITVTPVYADGPGSP---ESIKAYLKQAPPSKGPTVRTKKVGKN 533
+Y+ L ++ Y+ V V GPG P E I A PS GK
Sbjct 30122 PTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKE 30181
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDS--SHTEYTLSSLTSDTLYMV 590
+++W + D N I NY + R T VN D T ++SL Y
Sbjct 30182 HIIIQWTKPESDGGN-EISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQF 30240
Query 591 RMAAYTDEGGKDGPE----FTFTTPKFAQGEIEAI 621
R+ A G + E + P + G A
Sbjct 30241 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAP 30275
Score = 144 bits (363), Expect = 2e-33, Method: Composition-based stats.
Identities = 82/523 (16%), Positives = 160/523 (31%), Gaps = 47/523 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGG-RETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
PPE P ++ + E + W+ ++ + + + T + + + +
Sbjct 25731 PPEGPLKVTGVTAEKCYLA--WNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNY 25788
Query 184 VDYSTVYFVNIEVWVEAENALGK---VTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
+ V A N G + S + YK P PP V +
Sbjct 25789 KVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYK-PPGPPSTPEVSAI--TKDSM 25845
Query 241 KLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+TW P I Y ++ R K+ W++ + R V L Y FR+
Sbjct 25846 VVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLR--VTGLTEGHSYEFRV 25903
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
G G S+ S P PS D S + +V L W + P ++
Sbjct 25904 AAENAAGVGEPSEPSVFYRACDALYPP-GPPSNPKVTDTSRS----SVSLAW-SKPIYDG 25957
Query 360 NGKILDYEVTLTR-----WKSHLQNYTVNATKLTVNLT--NDRYLATLTVRNLVGKSDAA 412
+ Y V + W + + + TV N Y + N G + A
Sbjct 25958 GAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPA 26017
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQ 472
L + P ++ + + + + + + W++
Sbjct 26018 TLPGSVVAQERIEPPEIELDADLRKVVVLR----ASATLRLFV---TIKGRPEPEVKWEK 26070
Query 473 EDGTVHRTYLRGNLAESKCYLI-TV-------TPVYADGPGSPESIKAYLKQA-PPSKGP 523
+G + + +I V + + ++ ++ PS
Sbjct 26071 AEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPV 26130
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSL 582
+ ++V K+ L W+ P+ I NY + R + + + T + + +L
Sbjct 26131 NLTIREVKKDSVTLSWEP-PLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENL 26189
Query 583 TSDTLYMVRMAAYTDEGGKDGPEFT----FTTPKFAQGEIEAI 621
Y R+ A + G E T + P G + +
Sbjct 26190 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLV 26232
Score = 143 bits (361), Expect = 3e-33, Method: Composition-based stats.
Identities = 102/608 (17%), Positives = 179/608 (29%), Gaps = 84/608 (14%)
Query 41 HSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQ 100
+N V +K V + W P + ++ T + L +
Sbjct 17058 GTNVNIVAKIK-------GVPFPTLTWFKAPPKKPDNKEPVLYDT-------HVNKLVVD 17103
Query 101 LTCNILTF--GQLEQNVYGITIISGL----------------PPEKPKNLSCIVNEGKKM 142
TC ++ + + +Y IT ++ L PP P + +M
Sbjct 17104 DTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGP--IKFESVSADQM 17161
Query 143 RCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF-VNIEVWVE 199
W ++ TN+ ++ A K P CT + +
Sbjct 17162 TLSWFPPKDDGGSKITNYVIEKREANRKTW--VHVSSEPKECTYTIPKLLEGHEYVFRIM 17219
Query 200 AENALGK---VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIIL 255
A+N G + S+ ++ V P P +V + S + + W P +
Sbjct 17220 AQNKYGIGEPLDSEPETARNLFSV-PGAPDKPTVSSVTRNS--MTVNWEEPEYDGGSPVT 17276
Query 256 KYNIQYRTKDASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
Y ++ + + W ++ P + S+ V L ++Y FR+ + G G S
Sbjct 17277 GYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLP 17336
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
S+ A T D + + K+ L W P + K+ Y V
Sbjct 17337 SDPA---TARDPIAPPGPPFPKVTDWTKSSAD---LEWSP-PLKDGGSKVTGYIVEYKEE 17389
Query 374 KSHLQNYT----VNATKLTVNLTNDR--YLATLTVRNLVGKSDAAVLT--------IPAC 419
V TKL V + Y + N+ G + +T + +
Sbjct 17390 GKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP 17449
Query 420 DFQATHPVMDLKAFPKDNML----WVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
D Q V D ++ +V P + W + P E
Sbjct 17450 DLQLDASVRDRIVVHAGGVIRIIAYVSGKPPP------TVTWNMNERTLPQEATI--ETT 17501
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
+ + + N S + ++ G ++I + P G +
Sbjct 17502 AISSSMVIKNCQRSHQGVYSLLAKNEAGERK-KTIIVDVLDVPGPVGTPFLAHNLTNESC 17560
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
L W P D I NY I R T V + T+ L Y R+AA
Sbjct 17561 KLTWFS-PEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAA 17619
Query 595 YTDEGGKD 602
G
Sbjct 17620 ENSIGMGP 17627
Score = 139 bits (349), Expect = 7e-32, Method: Composition-based stats.
Identities = 96/563 (17%), Positives = 169/563 (30%), Gaps = 33/563 (6%)
Query 57 YFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVY 116
Y + W + + I T +T + N+Q + + NV+
Sbjct 31579 YIGRPVPAMTWFHGQKLLQNSENITIENTEH---YTHLVMKNVQRKTHAGKYKVQLSNVF 31635
Query 117 GI-----TIISGLPPEKPKNLSCIVNEGKKMRC-EWDGGRETHLE--TNFTLKSEWATHK 168
G + P+KP I K W + TN+ ++ A
Sbjct 31636 GTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEG 31695
Query 169 FADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK-----PN 223
+ + V A+N G SD + V +K P
Sbjct 31696 AEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGI--SDPLEVSSVVIIKSPFEKPG 31753
Query 224 PPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P ++ + W P S I Y ++ R K + W + E+ +
Sbjct 31754 APGKPTITAV--TKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIR--ET 31809
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
F+V++L EY FR++C G+ WS+ SE + + D P +AP F ++ + +
Sbjct 31810 VFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKS--DVPIQAPHFKEELRNLNVR 31867
Query 343 GYRTVQLVWK--TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN--DRYLA 398
LV K P E+ K +Q + +L + D +
Sbjct 31868 YQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVY 31927
Query 399 TLTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
+ N G A++ + + A V P ++
Sbjct 31928 QVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVIT 31987
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
W D +Q + + N E K V ++++ +
Sbjct 31988 WQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVA- 32046
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
P V+ V ++ L W + P I NY + + T
Sbjct 32047 DVPDPPRGVKVSDVSRDSVNLTWTE-PASDGGSKITNYIVEKCATTAERWLRVGQARETR 32105
Query 577 YTLSSLTSDTLYMVRMAAYTDEG 599
YT+ +L T Y R+ A G
Sbjct 32106 YTVINLFGKTSYQFRVIAENKFG 32128
Score = 137 bits (345), Expect = 2e-31, Method: Composition-based stats.
Identities = 113/658 (17%), Positives = 192/658 (29%), Gaps = 75/658 (11%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTAS--SVTF 91
PV S+ V K C + N + H+ + K + + V
Sbjct 19626 PGPV----SDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKK 19681
Query 92 TDIASLNIQLTCNILTFGQLEQNVYGITIISGLP-----------PEKPKNLSCIVNEGK 140
T N+ + N F N YG + + +P P+ P+ L
Sbjct 19682 TSFHVTNL-VPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKN 19740
Query 141 KMRCEWDGG------RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNI 194
W + T++ + E ++ + +D T
Sbjct 19741 SATLAWLPPLRDGGAKIDGYITSY-REEEQPADRWTEYSVVKDLSLVVTGLKEGKK---Y 19796
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
+ V A NA+G K + PP ++ E+++ IK+
Sbjct 19797 KFRVAARNAVGVSLPREAEGVYEAKEQLLPP---KILMPEQIT-----------IKAGKK 19842
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
L+ K T ED T S V + + + + GY+S +
Sbjct 19843 LRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIK--DVTRKDSGYYSLTA 19900
Query 315 EEASGITYE-------DRPSKA-PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
E +SG + D P P F L W +P + I +Y
Sbjct 19901 ENSSGTDTQKIKVVVMDAPGPPQPPFDI-----SDIDADACSLSW-HIPLEDGGSNITNY 19954
Query 367 EV-----TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
V + W + L + T + ++ + Y+ + N G S+ F
Sbjct 19955 IVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQF 20014
Query 422 Q---ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
+ P + ++V W P I+ + ++ K W + + T+
Sbjct 20015 PFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGY-LIERKERNSLLWVKANDTLV 20073
Query 479 RT--YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT-VRTKKVGKNEA 535
R+ Y L E Y + + G P Y+ P P V K+
Sbjct 20074 RSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTV 20133
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTLSSLTSDTLYMVR 591
L W P I Y + + G++ EYT + L Y R
Sbjct 20134 SLIW-ARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFR 20192
Query 592 MAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKK 649
A T E + A+ I + V + LLT G C + K
Sbjct 20193 AIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKP 20250
Score = 136 bits (343), Expect = 3e-31, Method: Composition-based stats.
Identities = 108/804 (13%), Positives = 221/804 (27%), Gaps = 124/804 (15%)
Query 33 PESPVVQLHS-----NFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTAS 87
P PV+ + + N + K + A K + + + + + +
Sbjct 27685 PSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERR--DLPDGRWT 27742
Query 88 SVTFTDIASLNIQLTC----NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
+FT++ ++ + F +N G P E ++CI +
Sbjct 27743 KASFTNVTETQFIISGLTQNSQYEFRVFARNAVG---SISNPSEVVGPITCIDSY----- 27794
Query 144 CEWDGGRETHLETNFTLKSEWATHKFADCKA---------------------------KR 176
GG L +T ++ +A +
Sbjct 27795 ----GGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVEN 27850
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
T + + + ++ NA+G ++ KP PP +
Sbjct 27851 TTDLASILIKDADRLNSGCYELKLRNAMGSASAT---IRVQILDKPGPPGGP-IEFKTVT 27906
Query 237 SSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+ + L W P+ I Y ++ R WS + ++ + EY
Sbjct 27907 AEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIK---GNEY 27963
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
+FR+R + + G G + E S + + P ++ ++ +VW + P
Sbjct 27964 IFRVRAVNKYGIG---EPLESDSVVAKNAFVTPGPPGIPEVT---KITKNSMTVVW-SRP 28016
Query 356 PFEANGKILDYEVTLTRWKSHL------QNYTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
+ I Y + KS + K+T N Y + N G+
Sbjct 28017 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 28076
Query 410 DAAVLTIP----ACDFQATHPVMDLKAFPKDNMLWVEWTTP----RESVKKYILEWCVLS 461
+ + P A + + + W+ P +V Y++E +
Sbjct 28077 PFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVE--IRQ 28134
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
+ T + Y+ NL Y V+ V G G P + ++ +
Sbjct 28135 GEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILE 28194
Query 522 GPTVRTKKVGKNEAVLEWDQ-----------LPVDVQNGFIRNYTIFYRTII---GNETA 567
P + + + + + P T+ +R G++
Sbjct 28195 APEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPP----------TVTWRKDEKNLGSDAR 28244
Query 568 VNVDSSHTE--YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPV 625
+++++ + T+ +T + + G + + V V
Sbjct 28245 YSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHV 28304
Query 626 CLA---------FLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF 676
+ + + KRD K+ W V K +
Sbjct 28305 SRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRT-WSVV--SHKCSSTSFKLIDLSEKTP 28361
Query 677 N----SKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSS 732
+ G + + A P DL D K I + GGS
Sbjct 28362 FFFRVLAENEIGIGEPCETTEPVKAAEVPAPI-RDLSMKDSTKTSVILSWTKPDFDGGSV 28420
Query 733 CMSSSRPSISSSDENESSQNTSST 756
++ S S T
Sbjct 28421 ITEYVVERKGKGEQTWSHAGISKT 28444
Score = 132 bits (331), Expect = 1e-29, Method: Composition-based stats.
Identities = 86/413 (21%), Positives = 136/413 (33%), Gaps = 38/413 (9%)
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNI 259
EN+ G ++ P PP NL+V E L W P + Y I
Sbjct 25025 ENSSGSKSA---FVTVKVLDTPGPPQNLAVK--EVRKDSAFLVWEPPIIDGGAKVKNYVI 25079
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
R ++ + + +++SF V++L Y FR+ E G G E
Sbjct 25080 DKRESTRKAYANVSSK---CSKTSFKVENLTEGAIYYFRVMAENEFGVGVP----VETVD 25132
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN 379
P P D S T L+W+ P + ++L Y V + + +
Sbjct 25133 AVKAAEPPSPPGKVTLTDVSQTSAS----LMWEK-PEHDGGSRVLGYVVEMQPKGTEKWS 25187
Query 380 YTVN----ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA-----CDFQATHPVMDL 430
+T + Y + N GKSD VL +P + +
Sbjct 25188 IVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNT 25247
Query 431 KAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR---GNLA 487
+ L +E + I W + T + T T L GN
Sbjct 25248 YSIQAGEDLKIE-IPVIGRPRPNI-SWVKDGEPLKQTTRV-NVEETATSTVLHIKEGNKD 25304
Query 488 ESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
+ Y TVT + G + L++ P GP VR +V + V+ W+ P
Sbjct 25305 DFGKY--TVTATNSAGTATENLSVIVLEKPGPPVGP-VRFDEVSADFVVISWEP-PAYTG 25360
Query 548 NGFIRNYTIFYR-TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
I NY + R T V+ + T ++ L + T Y R+ A G
Sbjct 25361 GCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYG 25413
Score = 131 bits (330), Expect = 1e-29, Method: Composition-based stats.
Identities = 79/531 (15%), Positives = 144/531 (27%), Gaps = 62/531 (12%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH---LETNFTLKSEWATHKFADCKAKRDTPTS 181
PP P+ L+ + +W R ++ K F KR PT+
Sbjct 16221 PPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFER-VNKRLCPTT 16279
Query 182 CTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
+ + E V+A N +G S +N P P L + +
Sbjct 16280 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVP-PTIKLRLS---VRGDTI 16335
Query 241 KLTWTNPSIKSVIILKY---NIQYRTKDA-------STWSQIPPEDTASTRSSFTVQDLK 290
K+ P + I++ + + + ++ ++
Sbjct 16336 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 16395
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
+ + + G + + DRPS + + L
Sbjct 16396 REDKGTYTVTASNRLGSVF------RNVHVEVYDRPSPPRNLAV-----TDIKAESCYLT 16444
Query 351 WKTLPPFEANGKILDYEVTLT-------RWKSHLQNYTVNATKLTVNLTNDRYLATLTVR 403
W P +I Y + W+ + + N +Y +
Sbjct 16445 WDA-PLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAV 16503
Query 404 NLVGKSD---AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
N G SD + + I P + V WT P ++ I + L
Sbjct 16504 NKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYW-L 16562
Query 461 SDKAPCITDWQQEDGT-VHRTYLRG------NLAESKCYLITVTPVYADGPGSPESIKAY 513
+ W + + + L+G L E Y + A G G P
Sbjct 16563 EKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSD- 16621
Query 514 LKQAP-----PSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NET 566
+ P P+ K K+ L W P I+ Y + + +
Sbjct 16622 -PEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKP-PAKDGGSPIKGYIVEMQEEGTTDWK 16679
Query 567 AVNVDS---SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFA 614
VN + E + +L Y R+ A + G + + T P
Sbjct 16680 RVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATD 16730
Score = 131 bits (328), Expect = 2e-29, Method: Composition-based stats.
Identities = 97/610 (16%), Positives = 177/610 (29%), Gaps = 86/610 (14%)
Query 40 LHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNI 99
+ + V EK M + +K +P ++Y + R +++ ++ + ++
Sbjct 15244 IGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISE 15303
Query 100 QLTCNILTFGQLEQ-NVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG-GRETHLETN 157
+ + I +I G P + W G+E
Sbjct 15304 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVP----TVSWHKDGKEVKASDR 15359
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPV 217
T+K++ + A + P S D + + EN LG T+ +
Sbjct 15360 LTMKNDHIS-------AHLEVPKSVRADAGI-----YTITL--ENKLGSATAS---INVK 15402
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPED 276
P P ++ + S KLTW P IL Y ++ R T+ +
Sbjct 15403 VIGLPGPCKDIKASDI--TKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM--- 15457
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ + S+TV+DL P EY FR++ + + G G + + + P
Sbjct 15458 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV-- 15515
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEV--------TLTRWKSHLQNYTVNATKLT 388
H + + WK P ++ KI+ Y + R HL K
Sbjct 15516 ---HNPTAEAMTITWKP-PLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAK-- 15569
Query 389 VNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM-------------------D 429
Y + N G S+ + T P
Sbjct 15570 GLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDAS 15629
Query 430 LKAFPKDNMLWV-------------EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
+ P + W+ K + E
Sbjct 15630 ISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKG 15689
Query 477 VHRTYLRGNLAESK-CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
+ +R +L Y+I V G + L P + + K
Sbjct 15690 ESQLRVRDSLRPDHGLYMIKVE--NDHGIAKAPCTVSVLD--TPGPPINFVFEDIRKTSV 15745
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTI---IGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+ +W+ P+D I NYT+ + V H +Y+++ L Y+ R+
Sbjct 15746 LCKWEP-PLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRV 15804
Query 593 AAYTDEGGKD 602
A G
Sbjct 15805 RAENRFGPGP 15814
Score = 129 bits (325), Expect = 4e-29, Method: Composition-based stats.
Identities = 92/618 (15%), Positives = 190/618 (31%), Gaps = 55/618 (9%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNV 115
+ + W+ + T+ + ++ + + + + + + L ++
Sbjct 26344 PFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSI 26403
Query 116 YG-ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR-ETHLE-TNFTLKSEWATHKFADC 172
ITII P P + + W+ + + +N+ ++ + T
Sbjct 26404 TVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHI 26463
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT--SDHINFDPVYKVKPNPPHNLSV 230
++ TS + T + V AEN GK + P PP V
Sbjct 26464 VSQAVARTSIKIVRLTTG-SEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKV 26522
Query 231 INSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
+++ S + +TW P + ++ Y+++Y+ + + WS+ A T+ V L
Sbjct 26523 VHA--TKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQM--KVSGL 26578
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
Y +R+ G G S E D P + ++V L
Sbjct 26579 DEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPE--------VTNITRKSVSL 26630
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQ------NYTVNATKLTVNLTNDRYLATLTVR 403
W + P ++ KI Y V N ++T + RY + R
Sbjct 26631 KW-SKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFAR 26689
Query 404 NLVGK-SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD 462
N S+ + T P P + +++ V+ +L+
Sbjct 26690 NAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVK--------AGEVLKINADIA 26741
Query 463 KAP-CITDWQQEDGTVHRTYLRGNLAESKCYLITV----------TPVYADGPGSPESIK 511
P + W ++ + ++ L+TV + S+
Sbjct 26742 GRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVA 26801
Query 512 AY---LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETA 567
L + P GP + + + L W + P + I Y + R T
Sbjct 26802 VNCKVLDKPGPPAGP-LEINGLTAEKCSLSWGR-PQEDGGADIDYYIVEKRETSHLAWTI 26859
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
+ T ++ L Y+ R+ G + P + + + P L
Sbjct 26860 CEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE-PLESVAIKALDPFTVPSP--PTSL 26916
Query 628 AFLLTTLLGVLFCFNKRD 645
T + C+++ +
Sbjct 26917 EITSVTKESMTLCWSRPE 26934
Score = 129 bits (323), Expect = 8e-29, Method: Composition-based stats.
Identities = 94/596 (16%), Positives = 169/596 (28%), Gaps = 74/596 (12%)
Query 61 NANYIVWK--TNHFTIPKEQYTIINRTASSVTFTDIASLNIQLT--------CNILTFGQ 110
++ Y+ WK + Y + R +S ++ +++ + + + N F
Sbjct 18251 DSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRV 18310
Query 111 LEQNVYGITIISG-----------LPPEKPKNLSCIVNEGKKMRCEWD-GGRETHLE-TN 157
+N YG PP PK+L + + ++ W+ R+ T
Sbjct 18311 AAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITG 18370
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPV 217
+ ++ + + K K T C V V+AEN +G D
Sbjct 18371 YLVEYQEEGTQ-DWIKFKTVTNLECVVTGLQQGK-TYRFRVKAENIVGLGLPD-TTIPIE 18427
Query 218 YKVKPNPPH-NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPED 276
+ K PP L V E L T P+ I+ + W+ E
Sbjct 18428 CQEKLVPPSVELDVKLIEGLVVKAGTTVRFPA---------IIRGVPVPTAKWTTDGSEI 18478
Query 277 TASTRSSFTVQD----------LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
+ + L+ T ++I G A +T D P
Sbjct 18479 KTDEHYTVETDNFSSVLTIKNCLRRDTG-EYQITVSNAAGSKT------VAVHLTVLDVP 18531
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK 386
+D + + + W+ P + +++Y V + + +
Sbjct 18532 GPPTGPINILDVTPEH----MTISWQP-PKDDGGSPVINYIVEKQDTRKDTWGVVSSGSS 18586
Query 387 LTVN-----LTNDRYLATLTVRNLVGKSDA--AVLTIPACDFQATHPVMDLKAFP-KDNM 438
T Y+ + N +G + T+ F P +N
Sbjct 18587 KTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENA 18646
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
V WT P+ I + + + + + L E Y V
Sbjct 18647 ATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFA 18706
Query 499 VYADGPGSPE----SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
G P IKA PP + K + A L W + P+ I Y
Sbjct 18707 ENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTK-PLSDGGSPILGY 18765
Query 555 TI-FYRTIIGNETAVNVDS--SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
+ + +N D + + L Y R+ A G + E
Sbjct 18766 VVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELA 18821
Score = 129 bits (323), Expect = 9e-29, Method: Composition-based stats.
Identities = 89/620 (14%), Positives = 169/620 (27%), Gaps = 82/620 (13%)
Query 23 ELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTII 82
E+ Y++ E P++ S V K +A W T K + +
Sbjct 20724 EISKDSAYVTWEPPIIDGGSPIINYVVQK--------RDAERKSWSTVTTECSKTSFRVA 20775
Query 83 NRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKM 142
N F + + N G + + + P +L
Sbjct 20776 NLEEGKSYFFRVFAE------NEYGIGDPGETRDAV--KASQTPGPVVDLKVRSVSKSSC 20827
Query 143 RCEWD-GGRETHLETN-FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
W + + + +K+ S V A
Sbjct 20828 SIGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYS---AKDLTEGKEYTFRVSA 20884
Query 201 ENALGKVTSDHINFDP-VYKVKPNP-----P---------HNLSVINSEELSSILKLTWT 245
EN G+ T I V P+ P N + + ++W
Sbjct 20885 ENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWK 20944
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
L + + + ++ + + D + +Y ++ +
Sbjct 20945 KGEDP----LATDTRVSVESSAVNTTLIVYDCQKSD----------AGKYTITLKNVAGT 20990
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
+G S + P+ F + L W P + +I +
Sbjct 20991 KEGTIS-----IKVVGKPGIPTGPIKF-------DEVTAEAMTLKWAP-PKDDGGSEITN 21037
Query 366 YEVTLT-----RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG-----KSDAAVLT 415
Y + +W + ++T Y ++ N G KS+ V
Sbjct 21038 YILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVAR 21097
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ--QE 473
P D P ++ D+ + + WT P+++ I + L K W+ +
Sbjct 21098 HP-FDVPDAPPPPNIVDVRHDS-VSLTWTDPKKTGGSPITGY-HLEFKERNSLLWKRANK 21154
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT-VRTKKVGK 532
R + L E Y V + G G P + P P + +
Sbjct 21155 TPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITR 21214
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMV 590
N L W + D + + Y + R + A +V+ +T++ L Y
Sbjct 21215 NSVTLIWTEPKYDGGH-KLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEF 21273
Query 591 RMAAYTDEGGKDGPEFTFTT 610
R+ A G P + T
Sbjct 21274 RIRAKNTAGAISAPSESTET 21293
Score = 125 bits (314), Expect = 1e-27, Method: Composition-based stats.
Identities = 76/442 (17%), Positives = 145/442 (33%), Gaps = 46/442 (10%)
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNI 259
EN GK + PN P + + ++++W P+ IL Y +
Sbjct 31137 ENKCGKK---AVYIKVRVIGSPNSPEGP-LEYDDIQVRSVRVSWRPPADDGGADILGYIL 31192
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ R + W I D+ +S V+ LK EY FR+ + G E +
Sbjct 31193 ERREVPKAAWYTI---DSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTP 31249
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR-----WK 374
T + P + +D + + +V L W + P + ++ Y + W
Sbjct 31250 KTPLNPPEPPSNPPEVLDVTKS----SVSLSW-SRPKDDGGSRVTGYYIERKETSTDKWV 31304
Query 375 SHLQNYTVNATKLTVNLTNDR-YLATLTVRNLVGKSDAAVLTIPAC-----DFQATHPVM 428
H + L D Y + +N VG S+ + + P D + +
Sbjct 31305 RHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGEL 31364
Query 429 DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV--HRTYLRGNL 486
++ + KD+ + ++W P K IL + V + W++ + + + G L
Sbjct 31365 EILSISKDS-VTLQWEKPECDGGKEILGYWVEYR-QSGDSAWKKSNKERIKDKQFTIGGL 31422
Query 487 AESKCYLITVTPVYADGPGSP-ESIKAYLKQAPPSKGPTVRTKKVGKN---------EAV 536
E+ Y V G P + + + + P +R +
Sbjct 31423 LEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 31482
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
+ LP I+ Y I + ++ D T+ + + + A
Sbjct 31483 IVGRPLP------DIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATN 31536
Query 597 DEGGKDGPEFTF--TTPKFAQG 616
+ G + TP+F G
Sbjct 31537 EVGEVETSSKLLLQATPQFHPG 31558
Score = 124 bits (311), Expect = 2e-27, Method: Composition-based stats.
Identities = 89/518 (17%), Positives = 152/518 (29%), Gaps = 58/518 (11%)
Query 137 NEGKKMRCEWDGGRETH---LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN 193
+ M W + K ++ C + P
Sbjct 15518 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCN-EHLVPILTYTAKGLEEGKE 15576
Query 194 IEVWVEAENALGKVTSDHINFDPVYKVKP-NPP-----HNLSVINSEEL--------SSI 239
+ V AENA G ++ P V P + P +L V +E+ S
Sbjct 15577 YQFRVRAENAAG-ISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 15635
Query 240 LKLTWTNPSIKSVIILKYNIQYRTK-----DASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+TW ++VI+ + I+ R + P T+ ++ + K
Sbjct 15636 PTITWIK--DENVIVPE-EIKKRAAPLVRRRKGEVQEEEPFVLPLTQ-RLSIDNSKKGES 15691
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGI-----TYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
R+R G + E GI T + P + + +V
Sbjct 15692 -QLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFE---DIRKTSVLC 15747
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT-------KLTVNLTNDRYLATLTV 402
W+ P + +I++Y + + V + +T + YL +
Sbjct 15748 KWEP-PLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRA 15806
Query 403 RNLVGKSDAAV---LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
N G V L P + N + V+W P+++ IL +
Sbjct 15807 ENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP-ILGYW- 15864
Query 460 LSDKAPCITDWQQEDGTVHRTYL--RGNLAESKCYLITVTPVYADGPG---SPESIKAYL 514
L + T W + + ++ L E Y+ V A GPG P K
Sbjct 15865 LEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAH 15924
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDS 572
P P R LEW+ P G I Y + + + NE
Sbjct 15925 DPISPPGPPIPRVTDTSSTTIELEWEP-PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMI 15983
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+YT+ + Y +R++A G E T
Sbjct 15984 KVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVT 16021
Score = 124 bits (310), Expect = 3e-27, Method: Composition-based stats.
Identities = 87/522 (17%), Positives = 157/522 (30%), Gaps = 64/522 (12%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P ++LS + + W + + T K + +C
Sbjct 28389 VPAPIRDLSMKDSTKTSVILSWTKPDFDGG--SVITEYVVERKGKGEQTWSHAGISKTCE 28446
Query 184 VDYSTVYFVNI-EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
++ S + ++ E V A+N G SD + P+ + + + + +++
Sbjct 28447 IEVSQLKEQSVLEFRVFAKNEKGL--SDPVTIGPITVKELIITPEVDLSDIPGAQVTVRI 28504
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTW---------SQIPPEDTASTRSSFTVQDLKP-- 291
+ L Y + + K + +W S+ + + ++++ K
Sbjct 28505 -----GHNVHLELPY--KGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEH 28557
Query 292 FTEYVFRI---RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
+Y + C + IT PSK +V
Sbjct 28558 GGKYTVILDNAVCRIAV----------PITVITL-GPPSKPKGPIR----FDEIKADSVI 28602
Query 349 LVWKTLPPFEANGKILDYEV-----TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVR 403
L W +P G+I Y + + T WK + K+ + + Y +
Sbjct 28603 LSWD-VPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAE 28661
Query 404 NLVGKSDAAVLTIPACDFQ---ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
N G S V +I Q P + + + + W P + +
Sbjct 28662 NRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTG-FHV 28720
Query 461 SDKAPCITDWQQE--DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
K WQ+ R Y L E Y V + G SP +
Sbjct 28721 EKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVS 28780
Query 519 PSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV-DSSHTE 576
P P T V + L+W+ P+ I Y+I R N D S +
Sbjct 28781 PVDPPGTPDYIDVTRETITLKWNP-PLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQ 28839
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEI 618
YT++ L+ Y R+ A G T + P + G I
Sbjct 28840 YTVTGLSPGDRYEFRIIARNAVG-------TISPPSQSSGII 28874
Score = 120 bits (301), Expect = 4e-26, Method: Composition-based stats.
Identities = 81/517 (16%), Positives = 139/517 (27%), Gaps = 77/517 (15%)
Query 138 EGKKMRCEWDGGRETH--LETNFTLKS------EWATHKFADCKAKRDTPTSCTVDYSTV 189
+ W + T++ ++ + C KRD V
Sbjct 16951 TKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN-KRDVEELQFTVEDLV 17009
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPP-------------HNLSVINSEEL 236
E V+A NA G K + PP N++++ +
Sbjct 17010 EGGEYEFRVKAVNAAGVSKPSATVGPVTVKDQTCPPSIDLKEFMEVEEGTNVNIVAKIKG 17069
Query 237 SSILKLTW--TNPSIK-SVIILKYNIQY-RTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
LTW P + + Y+ + T + + P+ S +T+
Sbjct 17070 VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTIT----- 17124
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
+ G S+E RP S Q + L W
Sbjct 17125 --------AVNNLG-----TASKEMRLNVL-GRPGPPVGPIKFESVSADQ----MTLSWF 17166
Query 353 TLPPFEANGKILDYEVTLTR----WKSHLQNYTVNATKLTVNLTND-RYLATLTVRNLVG 407
P + KI +Y + H+ + T L Y+ + +N G
Sbjct 17167 P-PKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYG 17225
Query 408 ------KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
+ + P + N + V W P + + +
Sbjct 17226 IGEPLDSEPETARNLFSVPGAPDKPTVS---SVTRNSMTVNWEEPEYDGGSPVTGYWLEM 17282
Query 462 DKAPCITDWQQEDG------TVHRTYLRGNLAESKCYLITVTPVYADGPGS---PESIKA 512
W++ + T+ +Y L E Y V + A G G P
Sbjct 17283 KDTTSKR-WKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPAT 17341
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS 572
P P + K+ A LEW P+ + Y + Y+ E D
Sbjct 17342 ARDPIAPPGPPFPKVTDWTKSSADLEWSP-PLKDGGSKVTGYIVEYKEEGKEEWEKGKDK 17400
Query 573 SH--TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
T+ ++ L Y R+ A G + E T
Sbjct 17401 EVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVT 17437
Score = 119 bits (298), Expect = 8e-26, Method: Composition-based stats.
Identities = 87/486 (18%), Positives = 159/486 (33%), Gaps = 40/486 (8%)
Query 138 EGKKMRCEWDGGRETH---LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNI 194
+ W ++ + + + E +T K+ K T+ V
Sbjct 31269 TKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR-HNKTQITTTMYTVTGLVPDAEY 31327
Query 195 EVWVEAENALGKVTSDHINFDPVYKV---KPNPPHNLSVINSEELSSILKLTWTNPS-IK 250
+ + A+N +G + + V K KP+ P L +++ + L W P
Sbjct 31328 QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSI--SKDSVTLQWEKPECDG 31385
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
IL Y ++YR S W + E FT+ L TEY FR+ E G
Sbjct 31386 GKEILGYWVEYRQSGDSAWKKSNKERIKDK--QFTIGGLLEATEYEFRVFAENETGL--- 31440
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK--TLPPFEANGKILDYEV 368
S A I + +AP ++ T+ QL + P + E+
Sbjct 31441 SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKEL 31500
Query 369 TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK--SDAAVLTIPACDFQATHP 426
+R + + + D + T N VG+ + + +L F +P
Sbjct 31501 IQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYP 31560
Query 427 VMDLKAFPKDNMLWVE----WTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
+ + + L + K ++ + T H T+L
Sbjct 31561 LKEKYYGAVGSTLRLHVMYIGRPVPAMT-------WFHGQKLLQNSENITIENTEHYTHL 31613
Query 483 R-GNLAESKC---YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
N+ Y + ++ V+ + ++ K P+ + + + KN AV+
Sbjct 31614 VMKNVQRKTHAGKYKVQLSNVFGTVDAILD-VEIQDKPDKPTGP--IVIEALLKNSAVIS 31670
Query 539 WDQLPVDVQNGFIRNYTI--FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
W P D +I NY + V+ S T + +LT + Y R++A
Sbjct 31671 WKP-PADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQN 31729
Query 597 DEGGKD 602
G D
Sbjct 31730 TFGISD 31735
Score = 116 bits (291), Expect = 5e-25, Method: Composition-based stats.
Identities = 90/591 (15%), Positives = 164/591 (28%), Gaps = 58/591 (10%)
Query 32 SPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTF 91
E V+ +K K W I K + T + +
Sbjct 31069 YQEGIFVRQGGVIRLTIPIKGKPFPICK-------WTKEGQDISKRAMIATSETHTELVI 31121
Query 92 TDIASLNIQLTCNILTFGQLEQNVYGITIISGLP--PEKPKNLSCIVNEGKKMRCEWDGG 149
+ + +L ++ VY + G P PE P L + + +R W
Sbjct 31122 KEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGP--LEYDDIQVRSVRVSWRPP 31179
Query 150 RETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV 207
+ + L+ R TS V V V AEN G
Sbjct 31180 ADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKE-NVEYHFRVSAENQFGIS 31238
Query 208 TS--DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTK 264
P + P P + + S + L+W+ P + Y I+ +
Sbjct 31239 KPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKET 31298
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
W + T T + +TV L P EY FRI + G S SE D
Sbjct 31299 STDKW--VRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFD 31356
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW------KSHLQ 378
+PS+ + +V L W+ P + +IL Y V + KS+ +
Sbjct 31357 KPSQPGELEIL-----SISKDSVTLQWEK-PECDGGKEILGYWVEYRQSGDSAWKKSNKE 31410
Query 379 NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA--AVLTIPACDFQATHPVM--DLKAFP 434
+ L Y + N G S ++I P + ++K
Sbjct 31411 RIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVT 31470
Query 435 K--DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR--GNLAESK 490
+ + ++W + ++ T +
Sbjct 31471 TKLGEAAQLSCQIVGRPLPD--IKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEG 31528
Query 491 CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW----DQLPVDV 546
Y T + S + + Q P + + L +P
Sbjct 31529 VYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMT 31588
Query 547 QNGFIRNYTIFYRTIIGNETAVNVDSSH--TEYTLSSLTSDTL---YMVRM 592
+ ++ N + ++++ T + ++ T Y V++
Sbjct 31589 W--------FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQL 31631
Score = 115 bits (288), Expect = 1e-24, Method: Composition-based stats.
Identities = 47/319 (15%), Positives = 91/319 (29%), Gaps = 24/319 (8%)
Query 216 PVYKVKPNPPHNLS--VINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQI 272
P+ + PP + E + + L+W P I Y+I+ R + W +
Sbjct 28575 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMV 28634
Query 273 PPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF 332
++ R++F V +L EY FR+R G S + + P
Sbjct 28635 C---SSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIP--GPPGK 28689
Query 333 WYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR----WKSHLQNYTVNATKL- 387
+ + + L W P ++ ++ + V + ++ +
Sbjct 28690 PVIYNVTSDG----MSLTWDA-PVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYR 28744
Query 388 -TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTT 445
T + Y + N G S + + P + ++W
Sbjct 28745 ATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNP 28804
Query 446 PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
P I+ + + + Y L+ Y + A G
Sbjct 28805 PLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTI 28864
Query 506 SPES----IKAYLKQAPPS 520
SP S I + P
Sbjct 28865 SPPSQSSGIIMTRDENVPP 28883
Score = 103 bits (255), Expect = 9e-21, Method: Composition-based stats.
Identities = 76/526 (14%), Positives = 141/526 (27%), Gaps = 62/526 (12%)
Query 126 PEKPKNLSCIVNEGKKMRCEWD-GGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCT 183
P +P L + + +W+ + E + ++ + K
Sbjct 31358 PSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQF 31417
Query 184 VDYSTVYFVNIEVWVEAENALG----KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ E V AEN G + T+ I P I E
Sbjct 31418 TIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPG-------IRKEMKDVT 31470
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
KL L I R W + E S + + + +
Sbjct 31471 TKL-------GEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDG----RTHTLTV 31519
Query 300 R-----------CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
C+ + G S+ T + P Y T +
Sbjct 31520 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMY 31579
Query 349 L-------VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLT 401
+ W N + +T+ + + N V +
Sbjct 31580 IGRPVPAMTWFHGQKLLQNSE----NITIENTEHYTHLVMKN-----VQRKTHAGKYKVQ 31630
Query 402 VRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
+ N+ G DA + + ++A K++ + + W P + +I + V
Sbjct 31631 LSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAV-ISWKPPADDGGSWITNYVVEK 31689
Query 462 DKAPCITDWQQEDGTVH-RTYLRGNLAESKCYLITVTPVYADGPGSP----ESIKAYLKQ 516
+A +WQ + T NL E+ Y V+ G P +
Sbjct 31690 CEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPF 31749
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSH 574
P V K+ V+ W P IRNY + R N+ + +
Sbjct 31750 EKPGAPGKPTITAVTKDSCVVAWKP-PASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 31808
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
T +++ +L Y R+ G + + P + ++
Sbjct 31809 TVFSVKNLIEGLEYEFRVKCENLGG--ESEWSEISEPITPKSDVPI 31852
Score = 77.6 bits (189), Expect = 6e-13, Method: Composition-based stats.
Identities = 87/518 (17%), Positives = 143/518 (28%), Gaps = 77/518 (15%)
Query 24 LLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIIN 83
LL IS + P S T V K + + W+ I I+N
Sbjct 31662 LLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAE-------WQLVSSAISVTTCRIVN 31714
Query 84 RTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLP---PEKPKNLSCIVNEGK 140
T ++ + +++ N TFG + +I P P P +
Sbjct 31715 LTENAGYYFRVSAQN--------TFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKD 31766
Query 141 KMRCEWDGGRETH---LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
W + + K E +K+ + T +V + + + E
Sbjct 31767 SCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSV-KNLIEGLEYEFR 31825
Query 198 VEAENALGKVTSDHIN--FDPVYKVKPNPPH------NLSVINSEELSSILKLT------ 243
V+ EN G+ I+ P V PH NL+V + + K+T
Sbjct 31826 VKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPI 31885
Query 244 --WTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
W + + LKY IQ + + Q+ T Y ++R
Sbjct 31886 VKWYRQGKEIIADGLKYRIQ---EFKGGYHQLIIASVTDDD----------ATVY--QVR 31930
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT--------QGYRTVQLVW- 351
G S E P G + W
Sbjct 31931 ATN-QGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQ 31989
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA 411
K + NG Y+V +TR S N + D + +N G D
Sbjct 31990 KGQDLIDNNG---HYQVIVTR--SFTSLVFPNGVE-----RKDAGFYVVCAKNRFGI-DQ 32038
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
+ + D + + +D+ + + WT P I + ++ A W
Sbjct 32039 KTVELDVADVPDPPRGVKVSDVSRDS-VNLTWTEPASDGGSKITNY-IVEKCATTAERWL 32096
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES 509
+ Y NL Y V G P
Sbjct 32097 RVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSE 32134
Score = 76.8 bits (187), Expect = 1e-12, Method: Composition-based stats.
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 12/129 (9%)
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILK 256
V A+N G D + P+PP + V + S + LTWT P S I
Sbjct 32028 VCAKNRFGI---DQKTVELDVADVPDPPRGVKVSDVSRDS--VNLTWTEPASDGGSKITN 32082
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y ++ A W ++ + +TV +L T Y FR+ + G S+ SE
Sbjct 32083 YIVEKCATTAERWLRVGQAR----ETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEP 32138
Query 317 ASGITYEDR 325
IT ED+
Sbjct 32139 --TITKEDK 32145
>sp|Q13332|PTPRS_HUMAN Receptor-type tyrosine-protein phosphatase
S OS=Homo sapiens OX=9606 GN=PTPRS PE=1 SV=3
Length=1948
Score = 249 bits (634), Expect = 6e-67, Method: Composition-based stats.
Identities = 111/620 (18%), Positives = 196/620 (32%), Gaps = 71/620 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRET-----HLETNFTLKSEWATHKFADCKAKRDTP 179
P P+N+ + M +W+ E +T++ E +
Sbjct 426 PASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQ---KHNVDD 482
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSS 238
+ T S + V V A ++G SD I V P P NL E S
Sbjct 483 SLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGV-PGQPMNLRAEARSETS- 540
Query 239 ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ L+W+ P +S I+KY + +R D T +S+ V+DLKP TEY FR
Sbjct 541 -ITLSWSPPRQES--IIKYELLFREGDHGR----EVGRTFDPTTSYVVEDLKPNTEYAFR 593
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+ G G + + T + +PS P + T + + W+ PP
Sbjct 594 LAARSPQGLGAF---TPVVRQRTLQSKPSAPPQDVKCVSVRST----AILVSWRPPPPET 646
Query 359 ANGKILDYEVTLT------RWKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSD 410
NG ++ Y V + T++ + +Y T VG
Sbjct 647 HNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGP 706
Query 411 AAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTP-----RESVKKYILEWCVLSDK 463
+ + D + P + V W +P ++ Y + + +
Sbjct 707 ESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGA 766
Query 464 APC-----------ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
W+ +D T + NL Y ITV G G+ K
Sbjct 767 EARGPPRIKDVMLADAQWETDD-TAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKV 825
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVD 571
+ + PT+ ++ + + W+ P + Y + + R +
Sbjct 826 VVTKGAVLGRPTLSVQQTPEGSLLARWEP-PAGTAEDQVLGYRLQFGREDSTPLATLEFP 884
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLL 631
S YT S + Y+ R+AA + G + + P+ I+ A
Sbjct 885 PSEDRYTASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAG 944
Query 632 TTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF--NSKDQMYSDGNFT 689
T LL L P VP I +++ + ++ +
Sbjct 945 TVLLRWL--------------PPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPG 990
Query 690 DVSVVEIEANDKKPFPEDLK 709
+ + ++ K DL+
Sbjct 991 AENALTLQGL-KPDTAYDLQ 1009
Score = 229 bits (583), Expect = 1e-60, Method: Composition-based stats.
Identities = 86/440 (20%), Positives = 165/440 (38%), Gaps = 42/440 (10%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A ++LG + + K P P V +E ++ + +TW + + Y I
Sbjct 313 AMSSLGVIEA---VAQITVKSLPKAPGTPMV--TENTATSITITWDSG--NPDPVSYYVI 365
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+Y++K QI + T + +++ L P +EY + + G+G SE
Sbjct 366 EYKSKSQDGPYQIKEDIT---TTRYSIGGLSPNSEYEIWVSAVNSIGQG---PPSESVVT 419
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH--- 376
T E P+ AP + T+ + W+ P E NG I Y V T H
Sbjct 420 RTGEQAPASAPRNV----QARMLSATTMIVQWEE--PVEPNGLIRGYRVYYTMEPEHPVG 473
Query 377 -LQNYTVNATKLTV---NLTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLK 431
Q + V+ + LT L ++ Y + VG + + + P+
Sbjct 474 NWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRA 533
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
+ + + W+ PR+ I+++ +L + + + +Y+ +L +
Sbjct 534 EARSETSITLSWSPPRQES---IIKYELLFREGDHGREVGR-TFDPTTSYVVEDLKPNTE 589
Query 492 YLITVTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y + G G+ ++ Q+ PS P V+ V ++ W P + NG
Sbjct 590 YAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNG 649
Query 550 FIRNYTIFYRTIIGNETAVN----VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ Y++ YR + + + + T+ L +L T Y + A+T+ G GPE
Sbjct 650 ALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVG--PGPE 707
Query 606 FTFTTPKFAQGEIEAIVVPV 625
+ P + + + P
Sbjct 708 SS---PVVVRTDEDVPSAPP 724
Score = 222 bits (565), Expect = 3e-58, Method: Composition-based stats.
Identities = 108/603 (18%), Positives = 193/603 (32%), Gaps = 65/603 (11%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
I P S + N CV Y+ W + E + R +T
Sbjct 249 ILPMSHEIMPGGNVNITCV-------AVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELT 301
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
+ TC ++ + + V IT+ S P+ P N + WD G
Sbjct 302 ---DVKDSANYTCVAMSSLGVIEAVAQITVKS--LPKAPGTPMVTENTATSITITWDSGN 356
Query 151 ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-TS 209
++ + + + + K D T+ E+WV A N++G+ S
Sbjct 357 PD--PVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPS 414
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA--- 266
+ + + + P N+ + I++ W P + +I Y + Y +
Sbjct 415 ESVVTRTGEQAPASAPRNVQARMLSATTMIVQ--WEEPVEPNGLIRGYRVYYTMEPEHPV 472
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
W + +D+ T TV L Y R+ G G SD T + P
Sbjct 473 GNWQKHNVDDSLLT----TVGSLLEDETYTVRVLAFTSVGDGPLSD---PIQVKTQQGVP 525
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ---NYTVN 383
+ + + + ++ L W I+ YE+ + +
Sbjct 526 GQPMNLR-----AEARSETSITLSWSPPRQE----SIIKYELLFREGDHGREVGRTFDPT 576
Query 384 ATKLTVNL-TNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDLK-AFPKDNMLW 440
+ + +L N Y L R+ G V+ + + P D+K + +
Sbjct 577 TSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAIL 636
Query 441 VEWTTPR-----ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLIT 495
V W P ++ Y + + L + P + T L L + Y IT
Sbjct 637 VSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTT-QILLEALEKWTQYRIT 695
Query 496 VTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
GPG + + PS P V + + + W Q+G IR
Sbjct 696 TVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRG 755
Query 554 YTIFYRTIIGNETAVNV---------------DSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
Y + Y + G E D++ E +++L +T Y + +AAYT +
Sbjct 756 YQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMK 815
Query 599 GGK 601
G
Sbjct 816 GDG 818
Score = 215 bits (547), Expect = 4e-56, Method: Composition-based stats.
Identities = 115/775 (15%), Positives = 218/775 (28%), Gaps = 125/775 (16%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGR-ETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P +P NL + W R E+ ++ + + + PT+
Sbjct 524 VPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREV----GRTFDPTTSY 579
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
V + A + G + + KP+ P V S+ + ++
Sbjct 580 VVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAP-PQDVKCVSVRSTAILVS 638
Query 244 WTNPSIK--SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
W P + + ++ Y+++YR + T + ++ L+ +T+Y
Sbjct 639 WRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVA 698
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
E G G S T ED PS P + ++++W++ P +G
Sbjct 699 HTEVGPGPESS---PVVVRTDEDVPSAPPRKVE----AEALNATAIRVLWRSPAPGRQHG 751
Query 362 KILDYEVTLTRWKSHLQNYT--------------VNATK-----LTVNLTNDRYLATLTV 402
+I Y+V R + + T +T Y T+
Sbjct 752 QIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAA 811
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD 462
+ G + + + L W P + + +L + +
Sbjct 812 YTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPAGTAEDQVLGYRLQFG 871
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+ E Y + + Y+ + G G + + + P
Sbjct 872 REDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAARSRGGLGEEAAEVLSIPEDTPRGH 931
Query 523 PTV--RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII----GNETAVN---VDSS 573
P + +L W +NG I YT+ R ET + +
Sbjct 932 PQILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPAAAEPGA 991
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTT 633
TL L DT Y +++ A+T G GP F+ P + + V P +
Sbjct 992 ENALTLQGLKPDTAYDLQVRAHTRRG--PGP---FSPPVRYRTFLRDQVSPKNFKVKMIM 1046
Query 634 LLGVLFCFNKRD------------------------------LIKKHIWPNVPDPSKSHI 663
VL + D L + V S +
Sbjct 1047 KTSVLLSWEFPDNYNSPTPYKIQYNGLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSL 1106
Query 664 AQWSPHTPPRHNFNSKDQMYSDGNFTDVS--VVEIEANDKKPFPEDL------------- 708
FN + S D ++ + + P P
Sbjct 1107 GGLQQTVTAWTAFNLLNGKPSVAPKPDADGFIMVYLPDGQSPVPVQSYFIVMVPLRKSRG 1166
Query 709 ----------KSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQ-NTSSTV 757
+ +DL + + + + S + RP I++ +
Sbjct 1167 GQFLTPLGSPEDMDLEELIQDISRLQRRSLRHSRQLEVPRPYIAARFSVLPPTFHPGDQK 1226
Query 758 QYSTV----VHSGYRHQVPSVQVFSRSEST-----------------QPLLDSEE 791
QY + G+R+ + + V +SE T QP++D EE
Sbjct 1227 QYGGFDNRGLEPGHRYVLFVLAVLQKSEPTFAASPFSDPFQLDNPDPQPIVDGEE 1281
Score = 165 bits (416), Expect = 5e-40, Method: Composition-based stats.
Identities = 82/524 (16%), Positives = 160/524 (31%), Gaps = 61/524 (12%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN---FTLKSEWATHKFADCKAKRDTP 179
P P+++ C+ + W ++++ + + K P
Sbjct 616 SKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIP 675
Query 180 --TSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEEL 236
T+ + + + + A +G S + V PP V
Sbjct 676 PTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPR--KVEAEALN 733
Query 237 SSILKLTWTNPSIK--SVIILKYNIQY-RTKDASTWSQIPPEDT----------ASTRSS 283
++ +++ W +P+ I Y + Y R + A +D +
Sbjct 734 ATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYE 793
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+ +L+P T Y + G G S + + P+ + P +
Sbjct 794 MVITNLQPETAYSITVAAYTMKGDGARSKP----KVVVTKGAVLGRPTLSVQQTPEGSLL 849
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKS----HLQNYTVNATKLTVNLTNDR-YLA 398
R W+ P A ++L Y + R S L+ + Y+
Sbjct 850 AR-----WEP-PAGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYVF 903
Query 399 TLTVRN--LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP-RESVKKYIL 455
L R+ +G+ A VL+IP + +++ + + W P I+
Sbjct 904 RLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAIV 963
Query 456 EWCVLSDKAPCITDWQQE------DGTVHRTYLRGNLAESKCYLITVTPVYADGPG---S 506
++ V +A + ++ + L Y + V GPG
Sbjct 964 KYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFSP 1023
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET 566
P + +L+ + K + K +L W+ D N Y I Y N
Sbjct 1024 PVRYRTFLRDQV--SPKNFKVKMIMKTSVLLSWEF--PDNYNSP-TPYKIQY-----NGL 1073
Query 567 AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
++VD T+ ++ L T Y + T+ G G T
Sbjct 1074 TLDVDGRTTKKLITHLKPHTFYNFVL---TNRGSSLGGLQQTVT 1114
Score = 138 bits (346), Expect = 1e-31, Method: Composition-based stats.
Identities = 57/260 (22%), Positives = 99/260 (38%), Gaps = 21/260 (8%)
Query 375 SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP 434
+ + V L + D T + +G + P +
Sbjct 286 TPEDDMPVGRNVLELTDVKDSANYTCVAMSSLG--VIEAVAQITVKSLPKAPGTPMVTEN 343
Query 435 KDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
+ + W + + V Y++E+ S P +Q ++ Y G L+ + Y
Sbjct 344 TATSITITWDSGNPDPVSYYVIEYKSKSQDGP----YQIKEDITTTRYSIGGLSPNSEYE 399
Query 494 ITVTPVYADGPGSP-ESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
I V+ V + G G P ES+ + P+ P V+ + + +++W++ NG I
Sbjct 400 IWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEE--PVEPNGLI 457
Query 552 RNYTIFY----RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
R Y ++Y +GN NVD S T+ SL D Y VR+ A+T G DGP
Sbjct 458 RGYRVYYTMEPEHPVGNWQKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVG--DGP--- 511
Query 608 FTTPKFAQGEIEAIVVPVCL 627
+ P + + P+ L
Sbjct 512 LSDPIQVKTQQGVPGQPMNL 531
Score = 107 bits (267), Expect = 3e-22, Method: Composition-based stats.
Identities = 73/459 (16%), Positives = 128/459 (28%), Gaps = 59/459 (13%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD---GGRETH----LET 156
+ G V + +P P+ + +R W GR+ +
Sbjct 700 TEVGPGPESSPVV-VRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQV 758
Query 157 NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF---------VNIEVWVEAENALGKV 207
++ K D + Y + V A G
Sbjct 759 HYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSITVAAYTMKGDG 818
Query 208 TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDA 266
P LSV + E S L W P+ + +L Y +Q+ +D+
Sbjct 819 ARSKPKVVVTKGAVLGRPT-LSVQQTPEGS--LLARWEPPAGTAEDQVLGYRLQFGREDS 875
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
+ + + + +T + YVFR+ G G + +E S ED P
Sbjct 876 TPLATLE---FPPSEDRYTASGVHKGATYVFRLAARSRGGLGE--EAAEVLSI--PEDTP 928
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW-----------KS 375
P ++ + TV L W P E NG I+ Y V + +
Sbjct 929 RGHPQI---LEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELPA 985
Query 376 HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA-FP 434
+ NA L + Y + G + + + K
Sbjct 986 AAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMI 1045
Query 435 KDNMLWVEWTTPRE--SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
+ + W P S Y +++ L+ DG + L +L Y
Sbjct 1046 MKTSVLLSWEFPDNYNSPTPYKIQYNGLTLD---------VDGRTTK-KLITHLKPHTFY 1095
Query 493 LITVTPVYADGPGSPESIKAYLK----QAPPSKGPTVRT 527
+T + G +++ A+ PS P
Sbjct 1096 NFVLTNRGSSLGGLQQTVTAWTAFNLLNGKPSVAPKPDA 1134
>sp|P14781|CNTN1_CHICK Contactin-1 OS=Gallus gallus OX=9031 GN=CNTN1
PE=1 SV=1
Length=1010
Score = 245 bits (625), Expect = 1e-66, Method: Composition-based stats.
Identities = 84/394 (21%), Positives = 139/394 (35%), Gaps = 24/394 (6%)
Query 230 VINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS--QIPPEDTASTRSSFTVQ 287
+ E + + LTW+ + I KY IQ +T + W + P D S V
Sbjct 601 IRIEEIRDTAVALTWSRGTDNHSPISKYTIQSKTFLSEEWKDAKTEPSDIEGNMESARVI 660
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV 347
DL P+ EY FRI G G S S+ T P+ APS R +
Sbjct 661 DLIPWMEYEFRIIATNTLGTGEPSMPSQ--RIRTEGAPPNVAPSDVGG----GGGSNREL 714
Query 348 QLVWKTLPPFEANGKILDYEVTLTR-WKSHLQNYTVNATKLTVNLTND-------RYLAT 399
+ W L G Y V + + TV ++ + D +Y
Sbjct 715 TITWMPLSREYHYGNNFGYIVAFKPFGEKEWRRVTVTNPEIGRYVHKDESMPPSTQYQVK 774
Query 400 LTVRNLVGKSDAAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTPRE-SVKKYILE 456
+ N G ++ + A D P + + V W E SV+ Y +
Sbjct 775 VKAFNSKGDGPFSLTAVIYSAQDAPTEVPTDVSVKVLSSSEISVSWHHVTEKSVEGYQIR 834
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-SIKAYLK 515
+ DK Q + NL + Y I V+ + G G P +I +
Sbjct 835 YWAAHDKEAAAQRVQV--SNQEYSTKLENLKPNTRYHIDVSAFNSAGYGPPSRTIDIITR 892
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT 575
+APPS+ P + + + ++ WD + + Y + YR +E + HT
Sbjct 893 KAPPSQRPRIISSVRSGSRYIITWDHVKAMSNESAVEGYKVLYRPDGQHEGKLFSTGKHT 952
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT 609
+ SD Y+V + A+++ G + + +
Sbjct 953 --IEVPVPSDGEYVVEVRAHSEGGDGEVAQIKIS 984
Score = 130 bits (326), Expect = 2e-29, Method: Composition-based stats.
Identities = 72/495 (15%), Positives = 156/495 (32%), Gaps = 40/495 (8%)
Query 38 VQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTI---PKEQY---TIINRTASSVTF 91
V + N T C+ ++ +I W N F I + ++ ++ ++ +
Sbjct 507 VTVGENATMQCI----ASHDPTLDLTFI-WSLNGFVIDFEKEHEHYERNVMIKSNGELLI 561
Query 92 TDIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
++ + + TC T ++ PP P + + W G
Sbjct 562 KNVQLRHAGRYTCTAQTIVDNSSA--SADLVVRGPPGPPGGIRIEEIRDTAVALTWSRGT 619
Query 151 ETHLE-TNFTLKSE-WATHKFADCKAKRD---TPTSCTVDYSTVYFVNIEVWVEAENALG 205
+ H + +T++S+ + + ++ D K + + ++ E + A N LG
Sbjct 620 DNHSPISKYTIQSKTFLSEEWKDAKTEPSDIEGNMESARVIDLIPWMEYEFRIIATNTLG 679
Query 206 KV-TSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSVI--ILKYNIQY 261
S PN P ++ + L +TW S + Y + +
Sbjct 680 TGEPSMPSQRIRTEGAPPNVAPSDVG--GGGGSNRELTITWMPLSREYHYGNNFGYIVAF 737
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+ W ++ + R + + P T+Y +++ G G +S A +
Sbjct 738 KPFGEKEWRRVTVTNPEIGRYVHKDESMPPSTQYQVKVKAFNSKGDGPFSL---TAVIYS 794
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
+D P++ P+ + + W + G + Y + + +
Sbjct 795 AQDAPTEVPTDVSV----KVLSSSEISVSWHHVTEKSVEGYQIRYWAAHDKEAAAQRVQV 850
Query 382 VN---ATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDLKAFPKDN 437
N +TKL N RY ++ N G + + I + + + +
Sbjct 851 SNQEYSTKLENLKPNTRYHIDVSAFNSAGYGPPSRTIDIITRKAPPSQRPRIISSVRSGS 910
Query 438 MLWVEWTTPRESVKKYILE-WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV 496
+ W + + +E + VL G + + Y++ V
Sbjct 911 RYIITWDHVKAMSNESAVEGYKVLYRPDGQHEGKLFSTGKHT---IEVPVPSDGEYVVEV 967
Query 497 TPVYADGPGSPESIK 511
G G IK
Sbjct 968 RAHSEGGDGEVAQIK 982
Score = 52.2 bits (123), Expect = 3e-05, Method: Composition-based stats.
Identities = 50/370 (14%), Positives = 109/370 (29%), Gaps = 44/370 (12%)
Query 382 VNATKLTVNLTN-DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW 440
+ + +N+T D T N GK+++ + + T +++ +N
Sbjct 456 DDGSLEIINVTKLDEGRYTCFAENNRGKANSTGVLEMTEATRITLAPLNVDVTVGENATM 515
Query 441 --VEWTTPRESV------KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
+ P + +++++ + + + + + C
Sbjct 516 QCIASHDPTLDLTFIWSLNGFVIDFEKEHEHYERNVMIKSNGELLIKNVQLRHAGRYTC- 574
Query 493 LITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
T + + S + + +R +++ L W + I
Sbjct 575 --TAQTIVDNSSASADLVVRGPP----GPPGGIRIEEIRDTAVALTWS--RGTDNHSPIS 626
Query 553 NYTIFYRTIIGNE------TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDG-P 604
YTI +T + E +++ + + L Y R+ A G G+ P
Sbjct 627 KYTIQSKTFLSEEWKDAKTEPSDIEGNMESARVIDLIPWMEYEFRIIATNTLGTGEPSMP 686
Query 605 EFTFTT----PKFAQGEIEAIV----------VPVCLAFLLTTLLGVLFCFNKRDLIKKH 650
T P A ++ +P+ + G + F K K+
Sbjct 687 SQRIRTEGAPPNVAPSDVGGGGGSNRELTITWMPLSREYHYGNNFGYIVAF-KPFGEKEW 745
Query 651 IWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMY---SDGNFTDVSVVEIEANDKKPFPED 707
V +P PP + K + + DG F+ +V+ + P D
Sbjct 746 RRVTVTNPEIGRYVHKDESMPPSTQYQVKVKAFNSKGDGPFSLTAVIYSAQDAPTEVPTD 805
Query 708 LKSLDLFKKE 717
+ L E
Sbjct 806 VSVKVLSSSE 815
>sp|F1NY98|DSCAM_CHICK Cell adhesion molecule DSCAM OS=Gallus
gallus OX=9031 GN=DSCAM PE=1 SV=3
Length=2034
Score = 248 bits (632), Expect = 1e-66, Method: Composition-based stats.
Identities = 115/595 (19%), Positives = 202/595 (34%), Gaps = 91/595 (15%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLET----NFTLKSEWATHK------FADCKAKRDTP 179
K +SC + K + W+ +E + + + ++ + +
Sbjct 831 KEMSCTAHGEKPIIVRWE--KEDRIINPEMSRYLVSTKEVGDEVISTLQILPTVREDSGF 888
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
SC A N+ G+ D + P+PP + E +
Sbjct 889 FSCH----------------AINSYGE---DRGIIQLTVQEPPDPPE---IEIREVRARS 926
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L WT + I Y+I+ + K S S +D + + T+ DL P + Y R+
Sbjct 927 IALRWTMGFDGNSPITGYDIECKNKSDSWDSVQRTKDVSPQLNQATIIDLHPSSTYNIRM 986
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
GK S+ S E + T E P P +++P +Q ++++ WK
Sbjct 987 YAKNRIGK---SEASNELTITTDEAAPDGPPQD-VQLEPISSQ---SIRVTWKAPKKHLQ 1039
Query 360 NGKILDYEVTLTRWKSHLQ--------NYTVNATKLTVNLTN--DRYLATLTVRN--LVG 407
NG I Y++ + + + T ++ T+N +Y + N +G
Sbjct 1040 NGIIRGYQIGYREYSAGGNFQFNIISIDTTGDSEVYTLNNLKKFTQYGMVVQACNRAGIG 1099
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI------LEWCVLS 461
S ++T D + P + + W+T + I + W L
Sbjct 1100 PSSQEIITTTLEDVPSCPPGNVQATATSPETISISWSTLAKETLNGILQGFRVIYWANLL 1159
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPS 520
D + T + L + Y I V G G E I K+ P
Sbjct 1160 DGELGEI---RNVTTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPG 1216
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF----YRTIIGNETAVNVDSSHTE 576
V+ + + W LP NG IR YT+F Y T+I E + DS
Sbjct 1217 PPAGVKAAASSASTVFVSW--LPPLKLNGIIRKYTVFCSHPYPTVIS-EFEASPDS--FS 1271
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLG 636
Y + +L+ + Y V + A T G + E P P + T+
Sbjct 1272 YRIPNLSRNRQYSVWVVAVTAAGRGNSSEIITVEPLAK--------APARILTFSGTVTT 1323
Query 637 VLFCFNKRDLIKKHIWP--NVPDPSKS-HIAQWSPHTPPRHNFNSKDQMYSDGNF 688
+K + P V DP+ + + S TP + + ++S+G+F
Sbjct 1324 --------PWMKDIVLPCKAVGDPAPTVKWMKDSNGTPSLVMIDGRRSIFSNGSF 1370
Score = 168 bits (426), Expect = 3e-41, Method: Composition-based stats.
Identities = 84/533 (16%), Positives = 167/533 (31%), Gaps = 42/533 (8%)
Query 95 ASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRET-- 152
++ NI++ N IT P P+++ + +R W ++
Sbjct 980 STYNIRMYAKNRIGKSEASNELTITTDEAAPDGPPQDVQLEPISSQSIRVTWKAPKKHLQ 1039
Query 153 -----HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV 207
+ + S +F + + F + V+A N G
Sbjct 1040 NGIIRGYQIGYREYSAGGNFQFNIISIDTTGDSEVYTLNNLKKFTQYGMVVQACNRAGIG 1099
Query 208 TSDH-INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK--SVIILKYNIQYRTK 264
S I + V PP N+ + + ++W+ + + + I+ + + Y
Sbjct 1100 PSSQEIITTTLEDVPSCPPGNVQATAT--SPETISISWSTLAKETLNGILQGFRVIY-WA 1156
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
+ + +T+ S + L+ +T Y ++ G G SE+ T ED
Sbjct 1157 NLLDGELGEIRNVTTTQPSLELDGLEKYTNYSIQVLAFTRAGDGV---RSEQIFTRTKED 1213
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT-RWKSHLQNYTVN 383
P + TV + W LPP + NG I Y V + + + + + +
Sbjct 1214 VPGPP-----AGVKAAASSASTVFVSW--LPPLKLNGIIRKYTVFCSHPYPTVISEFEAS 1266
Query 384 ATKLTVNLTN----DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD--- 436
+ + N +Y + G+ +++ + +A ++
Sbjct 1267 PDSFSYRIPNLSRNRQYSVWVVAVTAAGRGNSSEIITVEPLAKAPARILTFSGTVTTPWM 1326
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKAPCI--TDWQQEDGTVHRTYLRGNLAESKCYLI 494
+ + + ++W S+ P + D ++ + +R AE Y
Sbjct 1327 KDIVLPCKAVGDPAPT--VKWMKDSNGTPSLVMIDGRRSIFSNGSFVIRTVKAEDSGY-- 1382
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
A + I L+ P P + K + L W +P D IR Y
Sbjct 1383 --YSCVASNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSITLSW--IPGDNGGSSIRGY 1438
Query 555 TIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
+ Y + + S Y L +L T Y + A G E
Sbjct 1439 ILQYSEDNSEQWGSFPISPSERSYRLETLKCGTWYKFTLTAQNGVGPGRISEI 1491
Score = 146 bits (367), Expect = 4e-34, Method: Composition-based stats.
Identities = 93/552 (17%), Positives = 169/552 (31%), Gaps = 59/552 (11%)
Query 99 IQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLET-- 156
+ CN G Q + T+ +P P N+ + + W + L
Sbjct 1089 VVQACNRAGIGPSSQEIITTTLE-DVPSCPPGNVQATATSPETISISWSTLAKETLNGIL 1147
Query 157 ---NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN 213
+ + + + T S +D + N + V A G
Sbjct 1148 QGFRVIYWANLLDGELGEIRNVTTTQPSLELDGLE-KYTNYSIQVLAFTRAGDGVRSEQI 1206
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
F + P PP V + +S + ++W P + II KY + + I
Sbjct 1207 FTRTKEDVPGPPA--GVKAAASSASTVFVSWLPPLKLNGIIRKYTVFC---SHPYPTVIS 1261
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS------ 327
+ + S+ + +L +Y + + G+G + SE + P+
Sbjct 1262 EFEASPDSFSYRIPNLSRNRQYSVWVVAVTAAGRG---NSSEIITVEPLAKAPARILTFS 1318
Query 328 ---KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA 384
P + P G + W ++NG + R ++ +
Sbjct 1319 GTVTTPWMKDIVLPCKAVGDPAPTVKWM----KDSNGTPSLVMIDGRRSIFSNGSFVIRT 1374
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
K D + N G SD +L + P + + + + + W
Sbjct 1375 VKA-----EDSGYYSCVASNNWG-SDEIILNLQV-QVPPDQPRLTVSKT-TSSSITLSWI 1426
Query 445 TPRE---SVKKYILEWCVLSDKAPCITDWQQEDGT-VHRTYLRGNLAESKCYLITVTPVY 500
S++ YIL++ + + W + R+Y L Y T+T
Sbjct 1427 PGDNGGSSIRGYILQYSEDNSE-----QWGSFPISPSERSYRLETLKCGTWYKFTLTAQN 1481
Query 501 ADGPGS-PESIKAYL--KQAPPSKGPTVRTKKVGKNEAVLE---WDQLPVDVQNGFIRNY 554
GPG E I+A K+ SK + + L W+ I ++
Sbjct 1482 GVGPGRISEIIEAKTLGKEPQFSKEQELFA-SINTTRVRLNLIGWND-----GGCPITSF 1535
Query 555 TIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKF 613
T+ YR T S Y L L T Y ++M G + + F T +
Sbjct 1536 TLEYRPFGTTVWTTAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCAE-KQAKFATLNY 1594
Query 614 AQGEIEAIVVPV 625
I ++ V
Sbjct 1595 DGSTIPPLIKSV 1606
>sp|P97603|NEO1_RAT Neogenin (Fragment) OS=Rattus norvegicus OX=10116
GN=Neo1 PE=1 SV=1
Length=1377
Score = 247 bits (630), Expect = 1e-66, Method: Composition-based stats.
Identities = 115/642 (18%), Positives = 215/642 (33%), Gaps = 76/642 (12%)
Query 18 TESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKE 77
+ + E+LD + P S + + + CV + A I W N + E
Sbjct 209 LQESEEMLDLVFLMRPSSMIKVIGQSAVLPCV-------ASGLPAPVIRWMKNEDVLDTE 261
Query 78 QYTIINRT-ASSVTFTDIASLNIQ-LTCNILTFGQLEQNVYGITIISGLPPE---KPKNL 132
+ S+ +D+ + C + + + +PPE +P N+
Sbjct 262 SSGRLALLAGGSLEISDVTEDDAGTYFCVADNGNKTIEA--QAELTVQVPPEFLKQPANI 319
Query 133 ----------SCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSC 182
C V +W + + +++ + + + C
Sbjct 320 YARESMDIVFECEVTGKPAPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQC 379
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINF---DPVYKVKPNPPHNLSVINSEELSSI 239
AEN +G + P P V+ S +
Sbjct 380 I----------------AENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRF 423
Query 240 LKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+KLTW P S L Y++ Y TK+ ++ T+Q+L P T Y+F+
Sbjct 424 IKLTWRTPASDPHGDNLTYSVFY-TKEGVARERVENTSQPG-EMQVTIQNLMPATVYIFK 481
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDR--PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
+ + G G + S T + P AP+ ++ ++ + W+T P
Sbjct 482 VMAQNKHGSG---ESSAPLRVETQPEVQLPGPAPNIR-----AYATSPTSITVTWET--P 531
Query 357 FEANGKILDYEVTLTRWKS-HLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGK--SDA 411
NG+I +Y++ + Q+ V++ T+N Y + N G S
Sbjct 532 LSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQ 591
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK-KYILEWCVLSDKAPCITDW 470
V D + P + + W P + + I + + KA +D
Sbjct 592 DVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSATQNGQITGYKIRYRKASRKSDV 651
Query 471 QQ--EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP------ESIKAYLKQAPPSKG 522
+ GT + G L Y V + +G G E+ ++ L ++ +
Sbjct 652 TETVVTGTQLSQLIEG-LDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDESRVPEV 710
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
P+ + V+ W P + QN +R Y I Y + + VD YT+ +L
Sbjct 711 PSSLHVRPLVTSIVVSW--TPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENL 768
Query 583 TSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVV 623
+ Y++ + A+ + G G E T P E++ V+
Sbjct 769 DPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVI 810
Score = 185 bits (468), Expect = 2e-46, Method: Composition-based stats.
Identities = 122/643 (19%), Positives = 200/643 (31%), Gaps = 84/643 (13%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P V L S + D N Y V+ T + VT
Sbjct 411 PRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGVARERVENTSQPGEMQVTIQ 470
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLP-----------PEKPKNLSCIVNEGKK 141
++ + + F + QN +G S P P N+
Sbjct 471 NL------MPATVYIFKVMAQNKHGSG-ESSAPLRVETQPEVQLPGPAPNIRAYATSPTS 523
Query 142 MRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
+ W+ + E N+ L K D + D + + V A
Sbjct 524 ITVTWETPLSGNGEIQNYKLYY---MEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVA 580
Query 201 ENALGKVTSDH-INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKY 257
N G S + + V P NLS+ S + + W PS ++ I Y
Sbjct 581 YNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKS--IVIHWQPPSSATQNGQITGY 638
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW-SEE 316
I+YR S + T+ S ++ L TEY FR+ + +G G +DW S E
Sbjct 639 KIRYRKASRK--SDVTETVVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAE 696
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
++ + P T ++ + W PP N + Y + H
Sbjct 697 TFESDLDESRVPEVPSSLHVRPLVT----SIVVSW--TPPENQNIVVRGYAIGYGIGSPH 750
Query 377 LQNYTVN--ATKLTVNLTNDR--YLATLTVRNLVGK----------------SDAAVLTI 416
Q V+ T+ + Y+ TL N VG+ S+ + I
Sbjct 751 AQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVI 810
Query 417 -----PACDFQATHPVMDLKAFPKD-NMLWVEWTTPRE-------SVKKYILEWCVLSDK 463
P D P + ++A + + + W + Y + W
Sbjct 811 NAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKT---N 867
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKG 522
P T ++ + T YL L + Y +V + + + P+
Sbjct 868 IPANTKYKNANATTLS-YLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSP 926
Query 523 P---TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI----IGNETAVNVDSSHT 575
P TV +K+ ++ W P NG I Y I+Y T I + V +
Sbjct 927 PKDVTVVSKEGKPRTIIVNWQ--PPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRL 984
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF-TFTTPKFAQGE 617
+ + LT DT Y ++ A +G E F TPK +
Sbjct 985 THQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSD 1027
>sp|Q92859|NEO1_HUMAN Neogenin OS=Homo sapiens OX=9606 GN=NEO1
PE=1 SV=2
Length=1461
Score = 244 bits (622), Expect = 1e-65, Method: Composition-based stats.
Identities = 112/631 (18%), Positives = 209/631 (33%), Gaps = 77/631 (12%)
Query 30 YISPESPVVQL-HSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQY-TIINRTAS 87
++ SP+V++ + CV + I W N + E ++
Sbjct 251 FLKQPSPLVRVIGQDVVLPCV-------ASGLPTPTIKWMKNEEALDTESSERLVLLAGG 303
Query 88 SVTFTDIASLNIQ-LTCNILTFGQLEQNVYGITIISGLPPE---KPKNL----------S 133
S+ +D+ + C + + + PE +P N+
Sbjct 304 SLEISDVTEDDAGTYFCIADNGNETIEA--QAELTVQAQPEFLKQPTNIYAHESMDIVFE 361
Query 134 CIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN 193
C V +W + + +++ + + + C
Sbjct 362 CEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCI---------- 411
Query 194 IEVWVEAENALGKVTSDHINF---DPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SI 249
AEN +G + P P V+ S + +KLTW P S
Sbjct 412 ------AENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASD 465
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
L Y++ Y TK+ ++ T+Q+L P T Y+FR+ + G G
Sbjct 466 PHGDNLTYSVFY-TKEGIARERVENTSHPG-EMQVTIQNLMPATVYIFRVMAQNKHGSG- 522
Query 310 WSDWSEEASGITYEDR--PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
+ S T + P AP+ ++ ++ + W+T P NG+I +Y+
Sbjct 523 --ESSAPLRVETQPEVQLPGPAPNLR-----AYAASPTSITVTWET--PVSGNGEIQNYK 573
Query 368 VTLTRWKS-HLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGK--SDAAVLTIPACDFQ 422
+ + Q+ V++ T+N Y + N G S V D
Sbjct 574 LYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVP 633
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVK-KYILEWCVLSDKAPCITDWQQ--EDGTVHR 479
+ P + + W P + + I + + KA +D + GT
Sbjct 634 SAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTETLVSGTQLS 693
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSP------ESIKAYLKQAPPSKGPTVRTKKVGKN 533
+ G L Y V + +G G E+ ++ L + + P+ +
Sbjct 694 QLIEG-LDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVT 752
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
V+ W P + QN +R Y I Y + + VD YT+ +L + Y++ +
Sbjct 753 SIVVSW--TPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLK 810
Query 594 AYTDEG-GKDGPEFTFTTPKFAQGEIEAIVV 623
A+ + G G E T P E++ V+
Sbjct 811 AFNNVGEGIPLYESAVTRPHTDTSEVDLFVI 841
Score = 187 bits (474), Expect = 3e-47, Method: Composition-based stats.
Identities = 122/643 (19%), Positives = 202/643 (31%), Gaps = 84/643 (13%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P V L S + D N Y V+ T + + VT
Sbjct 442 PRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQ 501
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLP-----------PEKPKNLSCIVNEGKK 141
++ + + F + QN +G S P P NL
Sbjct 502 NL------MPATVYIFRVMAQNKHGSG-ESSAPLRVETQPEVQLPGPAPNLRAYAASPTS 554
Query 142 MRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
+ W+ + E N+ L K D + D + + V A
Sbjct 555 ITVTWETPVSGNGEIQNYKLYY---MEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVA 611
Query 201 ENALGKVTSDH-INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKY 257
N G S + + V P NLS+ S + + W P+ ++ I Y
Sbjct 612 YNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKS--IMIHWQPPAPATQNGQITGY 669
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW-SEE 316
I+YR S + + T+ S ++ L TEY FR+ + +G G +DW S E
Sbjct 670 KIRYRKASRK--SDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAE 727
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
++ + P T ++ + W PP N + Y + H
Sbjct 728 TFESDLDETRVPEVPSSLHVRPLVT----SIVVSW--TPPENQNIVVRGYAIGYGIGSPH 781
Query 377 LQNYTVN--ATKLTVNLTNDR--YLATLTVRNLVGK----------------SDAAVLTI 416
Q V+ T+ + Y+ TL N VG+ S+ + I
Sbjct 782 AQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVI 841
Query 417 -----PACDFQATHPVMDLKAFPKD-NMLWVEWTTPRE-------SVKKYILEWCVLSDK 463
P D P + ++A + + + W + Y + W
Sbjct 842 NAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKT---N 898
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKG 522
P T ++ + T YL L + Y +V + + + P+
Sbjct 899 IPANTKYKNANATTLS-YLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSP 957
Query 523 P---TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI----IGNETAVNVDSSHT 575
P TV +K+ ++ W P NG I Y I+Y T I + V +
Sbjct 958 PKDVTVVSKEGKPKTIIVNWQ--PPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRL 1015
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF-TFTTPKFAQGE 617
+ + LT DT Y ++ A +G E F TPK +
Sbjct 1016 THQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKADSSD 1058
>sp|Q7ZW34|CNTN5_DANRE Contactin-5 OS=Danio rerio OX=7955 GN=cntn5
PE=2 SV=1
Length=1056
Score = 242 bits (616), Expect = 2e-65, Method: Composition-based stats.
Identities = 105/640 (16%), Positives = 200/640 (31%), Gaps = 58/640 (9%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P + + + + C + + I W+ N + + ++ R +
Sbjct 444 PVRLIATVGKDVSLEC--RPRASPKPR-----ISWRKNDRRLQPSRRIMLLRNNTLRIIN 496
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLPPE---KPKNLSCIVNEGKKMRCEWDGG 149
S C Q ++ P P + V E + C
Sbjct 497 SSRSDEGSYVCRAEN--QFGSAELTTVLLVKEPMRVELSPLRVEVTVGESVVLSC----- 549
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPT---SCTVDYSTVYFVNIEVWVEAENALGK 206
+ TH + + + W + + + + +I + +
Sbjct 550 KVTH-DPSLDVSFLWLLNNQPLNTQQDGGHFEYIQTQSSTADLMIRSILLKHAGKYGCRA 608
Query 207 VTSDHINF---DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT 263
TS + + + P PP VI E +S L+W++ I YN+Q R+
Sbjct 609 QTSTDSVLAEAELLVRGPPGPPG--VVIVEEITASTATLSWSHGVDNHSPITTYNVQARS 666
Query 264 KDASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+ W + P+ + S DL P+ EY FR+ G G S S T
Sbjct 667 PVSLGWQTVKTDPDPVTGSMESAMAVDLNPWVEYEFRVVATNSIGTGDPSPPSRAVR--T 724
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL-----TRWKSH 376
E PS AP+ + + + W+ + NG+ Y V WK
Sbjct 725 KEAVPSVAPANVRGGN----GRRHELVISWEPVSEEYQNGEGFGYIVAFRVNGTRGWKEK 780
Query 377 LQNYTVNATKL---TVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDLKA 432
+ + T + + V N G + V+T+ + + + P +++A
Sbjct 781 MVTSADSTTYKYRDETFPPLTPFEVRVGVYNNKGDGPFSEVVTVFSAEGEPREPPSEVQA 840
Query 433 FP-KDNMLWVEWTTPR---ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
F + + V W P + Y + + ++ ++ L L
Sbjct 841 FAVSSSEIKVLWKPPSPGLGRPQGYEVSFWKDVEQEE--LGKKKRTLGNETNMLLSGLDG 898
Query 489 SKCYLITVTPVYADGPGSPES-IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
+ YL++V + G G + +K K+ PS P N L WD +
Sbjct 899 NTQYLVSVKGFNSAGQGPSSTAVKISTKKNAPSLPPGNLMWIQEGNNVSLSWDPVKARDN 958
Query 548 NGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
+ Y + R + V + + +L Y++ + A EGG+
Sbjct 959 ESEVIGYKVLLRQEGRGHS--QVMRTPNSAVVLTLPEGGTYIIEVRAV-SEGGEGAASAQ 1015
Query 608 FTTPKFAQ-----GEIEAIVVPVCLAFLLTTLLGVLFCFN 642
+ G++ P LA+ L ++ F
Sbjct 1016 VRVLTSSGVRAKNGQLSVQNSPPGLAWTALFLSLMVPSFP 1055
Score = 155 bits (392), Expect = 2e-37, Method: Composition-based stats.
Identities = 80/535 (15%), Positives = 159/535 (30%), Gaps = 50/535 (9%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQ------YTIINR 84
+SP V + + C K ++ +++ W N+ + +Q Y
Sbjct 532 LSPLRVEVTVGESVVLSC----KVTHDPSLDVSFL-WLLNNQPLNTQQDGGHFEYIQTQS 586
Query 85 TASSVTFTDIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
+ + + I + + C T + + ++ PP P +
Sbjct 587 STADLMIRSILLKHAGKYGCRAQTS--TDSVLAEAELLVRGPPGPPGVVIVEEITASTAT 644
Query 144 CEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPT----SCTVDYSTVYFVNIEVWV 198
W G + H T + +++ P + +V E V
Sbjct 645 LSWSHGVDNHSPITTYNVQARSPVSLGWQTVKTDPDPVTGSMESAMAVDLNPWVEYEFRV 704
Query 199 EAENALGKVTSDH--INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN--PSIKSVII 254
A N++G V P N+ L ++W ++
Sbjct 705 VATNSIGTGDPSPPSRAVRTKEAVPSVAPANVR--GGNGRRHELVISWEPVSEEYQNGEG 762
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
Y + +R W + ST + + P T + R+ G G + S
Sbjct 763 FGYIVAFRVNGTRGWKEKMVTSADSTTYKYRDETFPPLTPFEVRVGVYNNKGDGPF---S 819
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR-- 372
E + + E P + PS S + ++++WK P G+ YEV+ +
Sbjct 820 EVVTVFSAEGEPREPPSEVQAFAVSSS----EIKVLWKPPSP--GLGRPQGYEVSFWKDV 873
Query 373 -----WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT-IPACDFQATHP 426
K L+ N +YL ++ N G+ ++ I + P
Sbjct 874 EQEELGKKKRTLGNETNMLLSGLDGNTQYLVSVKGFNSAGQGPSSTAVKISTKKNAPSLP 933
Query 427 VMDLKAFPKDNMLWVEWTTPR-ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+L + N + + W + + ++ + VL +
Sbjct 934 PGNLMWIQEGNNVSLSWDPVKARDNESEVIGYKVLLRQEGRGHSQVMRTPNSAVVLT--- 990
Query 486 LAESKCYLITVTPVYADGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
L E Y+I V V G G+ ++ +K + + L W
Sbjct 991 LPEGGTYIIEVRAVSEGGEGAASAQVRVLTSSGVRAKNGQLSVQNSPPG---LAW 1042
>sp|Q9N3X8|SDK_CAEEL Protein sidekick homolog OS=Caenorhabditis
elegans OX=6239 GN=rig-4 PE=1 SV=2
Length=2325
Score = 243 bits (620), Expect = 3e-65, Method: Composition-based stats.
Identities = 111/528 (21%), Positives = 189/528 (36%), Gaps = 56/528 (11%)
Query 126 PEKP-KNLSCIVNEGKKMRCEWDGGRETHLETN---FTLKSEWATHKFADCKAKRDTPTS 181
P+ P + L + W TH + + + +S
Sbjct 1156 PDTPSQRLFAEPVSATSISVSWTPLLATHWNGQPKGYLIVYREIDDENWKEVRTPALRSS 1215
Query 182 CTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
F + EV V +EN G + +D + V P N+ V ++I+
Sbjct 1216 EHTVTDLRPFTSYEVNVFSENGFGRSLPTDSVKARTYESVPSGSPRNIVVTAEGSKAAII 1275
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWS-QIPPEDTASTRS-SFTVQDLKPFTEYVFR 298
K + ++ Y ++ + S + + D + V DL+PFT Y
Sbjct 1276 KWNPVAELSTNGDVIGYKLRVVPERESLMADETKVIDIPGQSTLMAKVSDLRPFTSYHVY 1335
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+ G G + S S T ED P+ SF + V++ W LPP
Sbjct 1336 MSAYTIVGNGP--ENSTPISFETMEDVPAPPESF-----QCSYISEQEVRMKW--LPPGS 1386
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT---------NDRYLATLTVRNLVGKS 409
NGKI +Y ++ WKSH L NL N +Y + RN G+S
Sbjct 1387 PNGKITNYIISY--WKSHEPRSMAIDAPLLGNLLMFAAMSLNPNTQYTFAIKARNSKGES 1444
Query 410 DAAVLTIPACDFQ-----ATHPVMDLKAFPKDNMLWVEW--------TTPRESVKKYILE 456
+ AV + + A PV D + + + + W T ES + +
Sbjct 1445 EEAVAEVMTSSVRLPVRNAPAPVRDTLSQHQATEIIIRWDESLPRKLTEDAESPVRAVQV 1504
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPV--YADGPGSPES-IKAY 513
+++ IT ++ + + R+ ++ +L+ + + + + + + SPES
Sbjct 1505 SYQKTNEDEWITLEKKFEYSKRRSVIK-HLSPNSMFRFRIRFIGDFLESSWSPESEWMRT 1563
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET----AVN 569
L AP ++ +++ +N LEW N Y I YR NET +
Sbjct 1564 LPSAPFAQPISLKATPYERNSVQLEWVVPHKSTWNSDAIGYRIHYREYPSNETWQMEEIA 1623
Query 570 VDSSH---TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFA 614
+ H E L+ L S Y++RM + EG F+ P FA
Sbjct 1624 IRDEHEDKEEKILAKLDSFKHYILRMRIFNSEGEGP-----FSAPVFA 1666
Score = 155 bits (392), Expect = 4e-37, Method: Composition-based stats.
Identities = 93/538 (17%), Positives = 176/538 (33%), Gaps = 50/538 (9%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN-----FTLKS-EWATHKFAD 171
+P P+N+ K +W+ E L TN + L+ AD
Sbjct 1249 ARTYESVPSGSPRNIVVTAEGSKAAIIKWNPVAE--LSTNGDVIGYKLRVVPERESLMAD 1306
Query 172 CKAKRDTPTSCTV---DYSTVYFVNIEVWVEAENALGKVT--SDHINFDPVYKVKPNPPH 226
D P T+ F + V++ A +G S I+F+ + V P PP
Sbjct 1307 ETKVIDIPGQSTLMAKVSDLRPFTSYHVYMSAYTIVGNGPENSTPISFETMEDV-PAPPE 1365
Query 227 NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 286
+ E +++ W P + I Y I Y K S F
Sbjct 1366 SFQCSYISE--QEVRMKWLPPGSPNGKITNYIISY-WKSHEPRSMAIDAPLLGNLLMFAA 1422
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
L P T+Y F I+ KG + E + AP+ D
Sbjct 1423 MSLNPNTQYTFAIKARNS--KGESEEAVAEVMTSSVRLPVRNAPAPVR--DTLSQHQATE 1478
Query 347 VQLVWKTLPP----FEANGKILDYEVTLTRWKSHLQ-------NYTVNATKLTVNLTNDR 395
+ + W P +A + +V+ + Y+ + + N
Sbjct 1479 IIIRWDESLPRKLTEDAESPVRAVQVSYQKTNEDEWITLEKKFEYSKRRSVIKHLSPNSM 1538
Query 396 YLATLTVRNLVGKSDAAVLT--IPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRESV-K 451
+ + +S + + + + LKA P + N + +EW P +S
Sbjct 1539 FRFRIRFIGDFLESSWSPESEWMRTLPSAPFAQPISLKATPYERNSVQLEWVVPHKSTWN 1598
Query 452 KYILEWCVLSDKAPCITDWQQEDGTV------HRTYLRGNLAESKCYLITVTPVYADGPG 505
+ + + + P WQ E+ + + L K Y++ + ++G G
Sbjct 1599 SDAIGYRIHYREYPSNETWQMEEIAIRDEHEDKEEKILAKLDSFKHYILRMRIFNSEGEG 1658
Query 506 S-PESIKAYLKQAPPSKG-PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
+ AY+ + P + + T+ + + ++WD P + I ++ + Y +
Sbjct 1659 PFSAPVFAYVGYSIPKRNLNNIITEPLSSSSIRVKWDAWPKEDSE-TITSFKVRYVPVAS 1717
Query 564 NETAVNVDS-----SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
++V+ + E TL+ L T Y + ++ Y G + T + G
Sbjct 1718 VLSSVSSEEEIMIVDTNECTLNDLRKFTEYQISVSPYNRAGEGKMSQVRDKTLEDKPG 1775
Score = 155 bits (391), Expect = 5e-37, Method: Composition-based stats.
Identities = 76/517 (15%), Positives = 159/517 (31%), Gaps = 41/517 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P P++ C +++R +W G TN+ + + +
Sbjct 1360 VPAPPESFQCSYISEQEVRMKWLPPGSPNGKITNYIISYWKSHEPRSMAIDAPLLGNLLM 1419
Query 184 VDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKP--NPPHNLSVINSEELSSIL 240
++ ++A N+ G+ P N P + S+ ++ +
Sbjct 1420 FAAMSLNPNTQYTFAIKARNSKGESEEAVAEVMTSSVRLPVRNAPAPVRDTLSQHQATEI 1479
Query 241 KLTWTNP------SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ W + + Y+ + W + + S R S ++ L P +
Sbjct 1480 IIRWDESLPRKLTEDAESPVRAVQVSYQKTNEDEWITLEKKFEYSKRRSV-IKHLSPNSM 1538
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR-TVQLVWKT 353
+ FRIR + + + WS SE T P P I T R +VQL W
Sbjct 1539 FRFRIRFIGDFLESSWSPESE--WMRTLPSAPFAQP-----ISLKATPYERNSVQLEWVV 1591
Query 354 LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR-----------YLATLTV 402
N + Y + + S+ + + Y+ + +
Sbjct 1592 PHKSTWNSDAIGYRIHYREYPSNETWQMEEIAIRDEHEDKEEKILAKLDSFKHYILRMRI 1651
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMD--LKAFPKDNMLWVEWTT----PRESVKKYILE 456
N G+ + + ++ + + + V+W E++ + +
Sbjct 1652 FNSEGEGPFSAPVFAYVGYSIPKRNLNNIITEPLSSSSIRVKWDAWPKEDSETITSFKVR 1711
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ ++ ++ ++ +L + Y I+V+P G G ++ +
Sbjct 1712 YVPVASVLSSVSSEEEIMIVDTNECTLNDLRKFTEYQISVSPYNRAGEGKMSQVRDKTLE 1771
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD---SS 573
P +R V + + WD+ NG + Y + Y+ E N D +S
Sbjct 1772 DKPGPVGILRFSDVLMDSVKVSWDE--PSQPNGNVIGYIVNYKGYRMQEEFKNEDQQRTS 1829
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ L Y + A T G + T
Sbjct 1830 RNYFDTHGLAEGVTYFFSVWAETSAGKGEQRSANVTI 1866
Score = 143 bits (360), Expect = 2e-33, Method: Composition-based stats.
Identities = 122/773 (16%), Positives = 232/773 (30%), Gaps = 69/773 (9%)
Query 67 WKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPP 126
W T IPKE+ T + + N G+ Y +T+ P
Sbjct 695 WTTAIDNIPKEEGKPCCWTDIEDLRPSSTAEFRVVASNKHGPGKPSLPSYSVTMPQQPPS 754
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRE---THLETNFTLKSEWATHKFADCKAKRDT--PTS 181
P+N++ + +W +E + + ++ A + K T
Sbjct 755 AAPRNVAASARSPHSVMVQWQQPKEELDSGDVLGYVVRYRLAGYSSLTWNEKNLTTKDAR 814
Query 182 CTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
T+ + + E+ V A N G V S+ I P N+ V S+ +
Sbjct 815 NTLVDELITWREYEIQVAAYNKRGLGVFSESIEVTTSEGRPTQAPKNVRVKVLN--STAV 872
Query 241 KLTWTNPSIK--SVIILKYNIQY---RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+ +T P + + L Y +Q+ + + Q+ D + + V +L+ F Y
Sbjct 873 AIEFTAPEQQRIPGVNLGYKVQFWKGEPEKGELYKQVI-LDPDRRQLTTVVNELEKFGHY 931
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
C G G S +T ED P ++ + V + W
Sbjct 932 NLTTLCFTTPGDG---PRSNVVKVVTEEDTP----ESVDELSIAEVMYNGAV-ITWN--S 981
Query 356 PFEANGKILDYEVTLTRWKS----HLQNYTVNATKLTVNLT--NDRYLATLTVRNLVGKS 409
P + NG + Y + S + T T++ + RY + G
Sbjct 982 PLKQNGIVTKYTIRHWAASSPDVKTKHEVDGSTTNFTIDGLQPSTRYGVDVMASTRKGDG 1041
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE-----SVKKYILEWCVLSDKA 464
+ + + + V+ +++++++E +
Sbjct 1042 PVEETKFESGVPPELPGRPSMLSIGDISATTVQLHFTPGFDGHTAIRQWVVEGKMADSSV 1101
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES---IKAYLKQAPPSK 521
R+ L Y + + G G+P L+ P +
Sbjct 1102 FAHVF--NVSAPKARSITVTGLRPFTQYQLRLIAENVKGRGAPSEPSRSFETLQTNPDTP 1159
Query 522 GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI-IGNETAVNVDS-SHTEYTL 579
+ + V + W L NG + Y I YR I N V + +E+T+
Sbjct 1160 SQRLFAEPVSATSISVSWTPLLATHWNGQPKGYLIVYREIDDENWKEVRTPALRSSEHTV 1219
Query 580 SSLTSDTLYMV---------------RMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVP 624
+ L T Y V + A T E G A+G AI+
Sbjct 1220 TDLRPFTSYEVNVFSENGFGRSLPTDSVKARTYESVPSGSPRNIV--VTAEGSKAAIIKW 1277
Query 625 VCLAFLLTTLLGVLFCFN---KRDLIKKHIWPNVPDPSKSHIAQWSPHTPP---RHNFNS 678
+A L T + + +R+ + + P +S + P H + S
Sbjct 1278 NPVAELSTNGDVIGYKLRVVPERESLMADETKVIDIPGQSTLMAKVSDLRPFTSYHVYMS 1337
Query 679 KDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSR 738
+ +G + E + P P + ++++ + GS +
Sbjct 1338 AYTIVGNGPENSTP-ISFETMEDVPAPPESFQCSYISEQEVRMKWLPP---GSPNGKITN 1393
Query 739 PSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEE 791
IS +E ++ P+ Q ++ +SEE
Sbjct 1394 YIISYWKSHEPRSMAIDAPLLGNLLMFAAMSLNPNTQYTFAIKARNSKGESEE 1446
Score = 137 bits (345), Expect = 2e-31, Method: Composition-based stats.
Identities = 109/651 (17%), Positives = 197/651 (30%), Gaps = 70/651 (11%)
Query 21 TGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYT 80
G+ L G P + +N C + ++ +V + W N +P +
Sbjct 544 NGDSLIEYG---PADQKSLIGTNVEFSCEVAKE-----YVRKASVEWYLNDVLLPVNGNS 595
Query 81 II----NRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIV 136
+ NR S + + C + G+ E + II P P+ + +
Sbjct 596 GLRISRNRKGSLIIRQVGPDNTGEYRCRVTVDGREENASAMLQIIEK--PAMPERVRAEL 653
Query 137 NE---GKKMRCEWDGGRETHLETNFT-----------LKSEWATHKFADCKAKRDTPTSC 182
+ K+R W+ G + + L S+W T D K + C
Sbjct 654 HNETMPAKVRVRWNEGFDGNEPIIKHAIEMRTMGPTGLWSDWTT--AIDNIPKEEGKPCC 711
Query 183 TVDYSTVY-FVNIEVWVEAEN--ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
D + E V A N GK + + + P N++
Sbjct 712 WTDIEDLRPSSTAEFRVVASNKHGPGKPSLPSYSVTMPQQPPSAAPRNVAASAR--SPHS 769
Query 240 LKLTWTNP--SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ + W P + S +L Y ++YR S+ + T + V +L + EY
Sbjct 770 VMVQWQQPKEELDSGDVLGYVVRYRLAGYSSLTWNEKNLTTKDARNTLVDELITWREYEI 829
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
++ + G G + SE T E RP++AP V + +
Sbjct 830 QVAAYNKRGLGVF---SESIEVTTSEGRPTQAPKNVRV----KVLNSTAVAIEFTAPEQQ 882
Query 358 EANGKILDYEVTLTRWKSH----------LQNYTVNATKLTVNLTNDRYLATLTVRNLVG 407
G L Y+V + + + T + Y T G
Sbjct 883 RIPGVNLGYKVQFWKGEPEKGELYKQVILDPDRRQLTTVVNELEKFGHYNLTTLCFTTPG 942
Query 408 KSD-AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD--KA 464
+ V+ + + A N + W +P + + ++ + +
Sbjct 943 DGPRSNVVKVVTEEDTPESVDELSIAEVMYNGAVITWNSPLKQ-NGIVTKYTIRHWAASS 1001
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP--PSKG 522
P + + DG+ + G L S Y + V G G E K P P +
Sbjct 1002 PDVKTKHEVDGSTTNFTIDG-LQPSTRYGVDVMASTRKGDGPVEETKFESGVPPELPGRP 1060
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSS---HTEYTL 579
+ + L P + IR + + + + A + S T+
Sbjct 1061 SMLSIGDISATTVQLH--FTPGFDGHTAIRQWVVEGKMADSSVFAHVFNVSAPKARSITV 1118
Query 580 SSLTSDTLYMVRMAAYT--DEGGKDGPEFTFTTPKF--AQGEIEAIVVPVC 626
+ L T Y +R+ A G P +F T + PV
Sbjct 1119 TGLRPFTQYQLRLIAENVKGRGAPSEPSRSFETLQTNPDTPSQRLFAEPVS 1169
Score = 108 bits (270), Expect = 1e-22, Method: Composition-based stats.
Identities = 55/344 (16%), Positives = 114/344 (33%), Gaps = 30/344 (9%)
Query 219 KVKPNPP--HNLSVINSEELSSILKLTWTNPSIK--SVIILKYNIQYRT-KDASTW--SQ 271
+ P+ P +S+ + + ++L W P + + Y I YR TW +
Sbjct 1562 RTLPSAPFAQPISLKATPYERNSVQLEWVVPHKSTWNSDAIGYRIHYREYPSNETWQMEE 1621
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
I D + + L F Y+ R+R +G+G +S G + P
Sbjct 1622 IAIRDEHEDKEEKILAKLDSFKHYILRMRIFNSEGEGPFSAPVFAYVGYSI-------PK 1674
Query 332 FWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN-------YTVNA 384
+ ++++ W P ++ I ++V S L + V+
Sbjct 1675 RNLNNIITEPLSSSSIRVKWDAWPKEDS-ETITSFKVRYVPVASVLSSVSSEEEIMIVDT 1733
Query 385 TKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE 442
+ T+N Y +++ N G+ + + + + + + + + V
Sbjct 1734 NECTLNDLRKFTEYQISVSPYNRAGEGKMSQVRDKTLEDKPGPVGILRFSDVLMDSVKVS 1793
Query 443 WTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPV 499
W P + V YI+ + + Q+ + + G LAE Y +V
Sbjct 1794 WDEPSQPNGNVIGYIVNYK-GYRMQEEFKNEDQQRTSRNYFDTHG-LAEGVTYFFSVWAE 1851
Query 500 YADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE-AVLEWDQL 542
+ G G S + + P + + L W+ +
Sbjct 1852 TSAGKGEQRSANVTIGPSKDGPPPPSKPQITSGQSYVTLNWNDV 1895
Score = 40.6 bits (93), Expect = 0.094, Method: Composition-based stats.
Identities = 36/248 (15%), Positives = 71/248 (29%), Gaps = 51/248 (21%)
Query 126 PEKPKNLSCIVNEGKKMRCEWD-GGRETHLETNFTLKSE-WATHKFADCKAKRDTPTSCT 183
P L ++ WD + + + + + + + ++ T +
Sbjct 1774 PGPVGILRFSDVLMDSVKVSWDEPSQPNGNVIGYIVNYKGYRMQEEFKNEDQQRTSRNYF 1833
Query 184 VDYSTVYFVNIEVWVEAENALGKV--TSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
+ V V AE + GK S ++ P P PP + S +
Sbjct 1834 DTHGLAEGVTYFFSVWAETSAGKGEQRSANVTIGPSKDGPP-PPSKPQIT---SGQSYVT 1889
Query 242 LTWTNPSIKSVIILKYNIQY-----------------RTKDAS----------------- 267
L W + + I+ + +Q R +
Sbjct 1890 LNWNDVADSDEIV-GHLLQAKRVSVAEEAPANGYVSQRPRRNEIKGAKSAAQTAAATSTR 1948
Query 268 ------TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
W + P + S + + ++L+P + Y FR+ G G S +E+
Sbjct 1949 PTHPIGEWITLRPTEGRSEKEQVSYRELQPSSYYAFRVFTRNVRGIGMASVETEQLFV-- 2006
Query 322 YEDRPSKA 329
E P
Sbjct 2007 PESIPDDP 2014
>sp|Q60ZN5|SDK_CAEBR Protein sidekick homolog OS=Caenorhabditis
briggsae OX=6238 GN=rig-4 PE=3 SV=1
Length=2322
Score = 242 bits (616), Expect = 1e-64, Method: Composition-based stats.
Identities = 109/527 (21%), Positives = 187/527 (35%), Gaps = 56/527 (11%)
Query 126 PEKP-KNLSCIVNEGKKMRCEWDGGRETHLETN---FTLKSEWATHKFADCKAKRDTPTS 181
PE P + L + W TH + + +S
Sbjct 1157 PETPSQRLFTEPVSATSISVSWTPLLATHWNGQPKGYLIVYREVDEDNWKEVRTPALRSS 1216
Query 182 CTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
F EV V +EN G + +D + V P N+ V S+I+
Sbjct 1217 EHTVTDLRPFTTYEVNVFSENVFGRSLPTDAVKARTYESVPSGSPRNIVVTAEGSKSAIV 1276
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT--VQDLKPFTEYVFR 298
K + ++ Y ++ + S + E +S+ V +L+PFT Y
Sbjct 1277 KWDPVAELSTNGDVIGYKLRVVPERESLMADETREIDVPGQSTLMTKVSNLRPFTSYYVY 1336
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+ G G + S S T ED P+ SF + V++ W LPP
Sbjct 1337 MSAYTIVGNGP--ENSTPLSFETLEDVPAPPESF-----QCSQISEQDVRMKW--LPPGS 1387
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT---------NDRYLATLTVRNLVGKS 409
NGKI +Y ++ WKSH ++ NL N +Y + +N G+S
Sbjct 1388 PNGKITNYVISY--WKSHEPRSMAIDAQVAGNLLMFSAMSLSPNTQYTFAIKAKNSKGES 1445
Query 410 DAAVLTIPACDFQ-----ATHPVMDLKAFPKDNMLWVEW--------TTPRESVKKYILE 456
+ AV + + A PV D + + + W T ES + +
Sbjct 1446 EEAVAEVMTSSVRLPVRNAPAPVRDTTSQHLATEITIRWDESLPRKLTEDAESPVRAVQV 1505
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPV--YADGPGSPES-IKAY 513
+++ +T ++ + + R ++ +L+ + + + + + + SPES
Sbjct 1506 SYQKTNEDEWLTLEKKFEYSKRRAVIK-HLSPNSMFRFRIRFIGDFLESSWSPESEWMRT 1564
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET----AVN 569
L AP ++ +++ +N LEW N Y I YR NET +
Sbjct 1565 LPSAPFAQPISLKATPYERNSVQLEWVVPHKSTWNSDAIGYRIHYREYPSNETWQMEEIA 1624
Query 570 VDSSH---TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKF 613
V H E L+ L++ Y++RM + EG F+ P F
Sbjct 1625 VHDPHEDREEKVLAKLSTFRHYIIRMRLFNSEGEGP-----FSAPVF 1666
Score = 161 bits (408), Expect = 5e-39, Method: Composition-based stats.
Identities = 82/517 (16%), Positives = 164/517 (32%), Gaps = 41/517 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P P++ C + +R +W G TN+ + + + +
Sbjct 1361 VPAPPESFQCSQISEQDVRMKWLPPGSPNGKITNYVISYWKSHEPRSMAIDAQVAGNLLM 1420
Query 184 VDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKP--NPPHNLSVINSEELSSIL 240
++ ++A+N+ G+ P N P + S+ L++ +
Sbjct 1421 FSAMSLSPNTQYTFAIKAKNSKGESEEAVAEVMTSSVRLPVRNAPAPVRDTTSQHLATEI 1480
Query 241 KLTWTNP------SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ W + + Y+ + W + + S R ++ L P +
Sbjct 1481 TIRWDESLPRKLTEDAESPVRAVQVSYQKTNEDEWLTLEKKFEYSKR-RAVIKHLSPNSM 1539
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR-TVQLVWKT 353
+ FRIR + + + WS SE T P P I T R +VQL W
Sbjct 1540 FRFRIRFIGDFLESSWSPESE--WMRTLPSAPFAQP-----ISLKATPYERNSVQLEWVV 1592
Query 354 LPPFEANGKILDYEVTLTRWKSH----LQNYTVNATK-------LTVNLTNDRYLATLTV 402
N + Y + + S+ ++ V+ L T Y+ + +
Sbjct 1593 PHKSTWNSDAIGYRIHYREYPSNETWQMEEIAVHDPHEDREEKVLAKLSTFRHYIIRMRL 1652
Query 403 RNLVGKSD--AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT----PRESVKKYILE 456
N G+ A V + + + + V+W E+V + +
Sbjct 1653 FNSEGEGPFSAPVFVYVGYSIPKRNLTNIITEPLSSSSIRVKWDAWPKEDSETVTSFKVR 1712
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ ++ ++ ++ + +L + Y I+V+P G G ++ +
Sbjct 1713 YVPVASVLSSVSSEEEVMIVDTNECILSDLRKFAEYQISVSPYNRAGEGKMSQVREKTLE 1772
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD---SS 573
P +R V + + WD+ NG + Y + Y+ E N D +S
Sbjct 1773 DKPGPVGVLRFSDVLMDSVKVSWDE--PAQPNGMVIGYIVNYKGYRMQEEFKNEDQQRTS 1830
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ L Y + A T G + T
Sbjct 1831 RNYFDSHGLAEGVTYFFSVWAETSAGKGELRSANVTI 1867
Score = 160 bits (403), Expect = 2e-38, Method: Composition-based stats.
Identities = 99/604 (16%), Positives = 201/604 (33%), Gaps = 68/604 (11%)
Query 75 PKEQYTIINRTASSVTFTDIASLNIQLTCNI---------LTFGQLEQNVYGITI----- 120
+ Y I+ R + ++ + ++ + + +NV+G ++
Sbjct 1189 QPKGYLIVYREVDEDNWKEVRTPALRSSEHTVTDLRPFTTYEVNVFSENVFGRSLPTDAV 1248
Query 121 ----ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN-----FTLKS-EWATHKFA 170
+P P+N+ K +WD E L TN + L+ A
Sbjct 1249 KARTYESVPSGSPRNIVVTAEGSKSAIVKWDPVAE--LSTNGDVIGYKLRVVPERESLMA 1306
Query 171 DCKAKRDTPTSCTV---DYSTVYFVNIEVWVEAENALGKVT--SDHINFDPVYKVKPNPP 225
D + D P T+ + F + V++ A +G S ++F+ + V P PP
Sbjct 1307 DETREIDVPGQSTLMTKVSNLRPFTSYYVYMSAYTIVGNGPENSTPLSFETLEDV-PAPP 1365
Query 226 HNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
+ E +++ W P + I Y I Y K S A F+
Sbjct 1366 ESFQCSQISEQD--VRMKWLPPGSPNGKITNYVISY-WKSHEPRSMAIDAQVAGNLLMFS 1422
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
L P T+Y F I+ KG + E + AP+ D +
Sbjct 1423 AMSLSPNTQYTFAIKAKNS--KGESEEAVAEVMTSSVRLPVRNAPAPVR--DTTSQHLAT 1478
Query 346 TVQLVWKTLPP----FEANGKILDYEVTLTRWKSHLQ-------NYTVNATKLTVNLTND 394
+ + W P +A + +V+ + Y+ + N
Sbjct 1479 EITIRWDESLPRKLTEDAESPVRAVQVSYQKTNEDEWLTLEKKFEYSKRRAVIKHLSPNS 1538
Query 395 RYLATLTVRNLVGKSDAAVLT--IPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRESV- 450
+ + +S + + + + LKA P + N + +EW P +S
Sbjct 1539 MFRFRIRFIGDFLESSWSPESEWMRTLPSAPFAQPISLKATPYERNSVQLEWVVPHKSTW 1598
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVH------RTYLRGNLAESKCYLITVTPVYADGP 504
+ + + + P WQ E+ VH + L+ + Y+I + ++G
Sbjct 1599 NSDAIGYRIHYREYPSNETWQMEEIAVHDPHEDREEKVLAKLSTFRHYIIRMRLFNSEGE 1658
Query 505 GS-PESIKAYLKQAPPSKG-PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII 562
G + Y+ + P + + T+ + + ++WD P + + ++ + Y +
Sbjct 1659 GPFSAPVFVYVGYSIPKRNLTNIITEPLSSSSIRVKWDAWPKEDSE-TVTSFKVRYVPVA 1717
Query 563 GNETAVNVDS-----SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
++V+ + E LS L Y + ++ Y G + T + G
Sbjct 1718 SVLSSVSSEEEVMIVDTNECILSDLRKFAEYQISVSPYNRAGEGKMSQVREKTLEDKPGP 1777
Query 618 IEAI 621
+ +
Sbjct 1778 VGVL 1781
Score = 149 bits (375), Expect = 5e-35, Method: Composition-based stats.
Identities = 84/506 (17%), Positives = 157/506 (31%), Gaps = 46/506 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRE---THLETNFTLKSEWATHKFADCKAKRDT--P 179
P P+N++ + +W +E + + ++ A + K T
Sbjct 754 PSAAPRNVAASARSPHSVMVQWQQPKEEQDSGDFLGYVVRYRLAGYSSLTWNEKNLTTKD 813
Query 180 TSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
T+ + + E+ V A N G V S+ I P N+ V S+
Sbjct 814 ARNTLVDELITWREYEIQVAAYNKRGLGVFSESIEVTTAEGRPTQAPKNVRVKVLN--ST 871
Query 239 ILKLTWTNPSIK--SVIILKYNIQY---RTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
+ L +T P + + L Y +Q+ + + Q+ D + S V +L+ F
Sbjct 872 AVSLEFTAPEQQRIPGVNLGYKVQFWKGEPEKGELYKQVI-LDPDRRQLSTVVNELEKFG 930
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
Y + C G G S +T ED P +A + + L W
Sbjct 931 HYNLTVLCFTTPGDG---PKSNILRVVTEEDTP-EAVDELSIAEVMYNGA----VLTWNP 982
Query 354 LPPFEANGKILDYEVTLTRWKS----HLQNYTVNATKLTVNLT--NDRYLATLTVRNLVG 407
NG + Y + S + T +T++ + RY + G
Sbjct 983 PMKE--NGIVTKYTIRHWASSSPDVKTKHEVDGSTTNITIDGLQPSTRYGVDVMASTKKG 1040
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE-----SVKKYILEWCVLSD 462
+ + + + V+ +++++I+E +
Sbjct 1041 DGPVEETKFESGVPPELPGRPSMLSIGDISATTVQLHFTPGFDGHTAIRQWIVEGKMADS 1100
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY-----LKQA 517
R+ + L Y + + G G+P
Sbjct 1101 SVFAHIF--NVSSPKARSIIVTGLRPFTQYQLRLIAENVKGRGAPSEPSRTFETLQTNPE 1158
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDS-SHT 575
PS+ + T+ V + W L NG + Y I YR + N V + +
Sbjct 1159 TPSQR--LFTEPVSATSISVSWTPLLATHWNGQPKGYLIVYREVDEDNWKEVRTPALRSS 1216
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGK 601
E+T++ L T Y V + + G
Sbjct 1217 EHTVTDLRPFTTYEVNVFSENVFGRS 1242
Score = 141 bits (356), Expect = 8e-33, Method: Composition-based stats.
Identities = 132/803 (16%), Positives = 236/803 (29%), Gaps = 98/803 (12%)
Query 21 TGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYT 80
G+ L G P + +N C + ++ + + W N +P +
Sbjct 545 NGDSLIEYG---PADQKSLIGTNVEFSCEVAKE-----YARKATVEWYLNDALLPVNGNS 596
Query 81 II----NRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIV 136
+ NR S + + C + G+ E + II P P+ + +
Sbjct 597 GLRISRNRKGSLIIRQVGPDNTGEYRCRVTVDGREENASAMLQIIEK--PAMPERVRAEL 654
Query 137 NE---GKKMRCEWDGGRETHLETNFT-----------LKSEWATHKFADCKAKRDTPTSC 182
+ K+R W+ G + + L S+W T D K D C
Sbjct 655 HNETMPAKVRVRWNEGFDGNEPIIKHAIEIRTMGPTGLWSDWTT--AIDNIPKDDGKPCC 712
Query 183 TVDYSTVY-FVNIEVWVEAEN--ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
D + E V A N GK + + + P N++
Sbjct 713 WADIEDLRPSSTAEFRVVASNKHGPGKPSLPSSSVTMPQQPPSAAPRNVAASAR--SPHS 770
Query 240 LKLTWTNP--SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ + W P S L Y ++YR S+ + T + V +L + EY
Sbjct 771 VMVQWQQPKEEQDSGDFLGYVVRYRLAGYSSLTWNEKNLTTKDARNTLVDELITWREYEI 830
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
++ + G G + SE T E RP++AP V L +
Sbjct 831 QVAAYNKRGLGVF---SESIEVTTAEGRPTQAPKNVRV----KVLNSTAVSLEFTAPEQQ 883
Query 358 EANGKILDYEVTLTRWKSH----------LQNYTVNATKLTVNLTNDRYLATLTVRNLVG 407
G L Y+V + + + +T + Y T+ G
Sbjct 884 RIPGVNLGYKVQFWKGEPEKGELYKQVILDPDRRQLSTVVNELEKFGHYNLTVLCFTTPG 943
Query 408 KSD-AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD--KA 464
+ +L + + A N + W P + + ++ + +
Sbjct 944 DGPKSNILRVVTEEDTPEAVDELSIAEVMYNGAVLTWNPPMKE-NGIVTKYTIRHWASSS 1002
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP--PSKG 522
P + + DG+ + G L S Y + V G G E K P P +
Sbjct 1003 PDVKTKHEVDGSTTNITIDG-LQPSTRYGVDVMASTKKGDGPVEETKFESGVPPELPGRP 1061
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH---TEYTL 579
+ + L P + IR + + + + A + S +
Sbjct 1062 SMLSIGDISATTVQLH--FTPGFDGHTAIRQWIVEGKMADSSVFAHIFNVSSPKARSIIV 1119
Query 580 SSLTSDTLYMVRMAAYT--DEGGKDGPEFTFTTPKFAQ--GEIEAIVVPVCLAFLLTTLL 635
+ L T Y +R+ A G P TF T + PV + +
Sbjct 1120 TGLRPFTQYQLRLIAENVKGRGAPSEPSRTFETLQTNPETPSQRLFTEPVSATSISVSWT 1179
Query 636 GVLFCFNKRD---------LIKKHIWPNVPDPS----KSHIAQWSPHTPPRHNFNSKDQM 682
+L + + W V P+ + + P T N S + +
Sbjct 1180 PLLATHWNGQPKGYLIVYREVDEDNWKEVRTPALRSSEHTVTDLRPFTTYEVNVFS-ENV 1238
Query 683 YSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKI---------NTEGHSSGIGGSSC 733
+ TD + P ++ K I +T G IG
Sbjct 1239 FGRSLPTDAVKARTYESVPSGSPRNIVVTAEGSKSAIVKWDPVAELSTNGD--VIGYKLR 1296
Query 734 MSSSRPSISSSDENE---SSQNT 753
+ R S+ + + E Q+T
Sbjct 1297 VVPERESLMADETREIDVPGQST 1319
Score = 101 bits (251), Expect = 2e-20, Method: Composition-based stats.
Identities = 51/343 (15%), Positives = 110/343 (32%), Gaps = 28/343 (8%)
Query 219 KVKPNPP--HNLSVINSEELSSILKLTWTNPSIK--SVIILKYNIQYRT-KDASTW--SQ 271
+ P+ P +S+ + + ++L W P + + Y I YR TW +
Sbjct 1563 RTLPSAPFAQPISLKATPYERNSVQLEWVVPHKSTWNSDAIGYRIHYREYPSNETWQMEE 1622
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
I D R + L F Y+ R+R +G+G +S G + P
Sbjct 1623 IAVHDPHEDREEKVLAKLSTFRHYIIRMRLFNSEGEGPFSAPVFVYVGYSI-------PK 1675
Query 332 FWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL 391
+ ++++ W P ++ + ++V S L + + + V+
Sbjct 1676 RNLTNIITEPLSSSSIRVKWDAWPKEDS-ETVTSFKVRYVPVASVLSSVSSEEEVMIVDT 1734
Query 392 TN---------DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE 442
Y +++ N G+ + + + + + + + + V
Sbjct 1735 NECILSDLRKFAEYQISVSPYNRAGEGKMSQVREKTLEDKPGPVGVLRFSDVLMDSVKVS 1794
Query 443 WTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG--NLAESKCYLITVTPVY 500
W P + ++ + V +++ ED LAE Y +V
Sbjct 1795 WDEPAQP-NGMVIGYIVNYKGYRMQEEFKNEDQQRTSRNYFDSHGLAEGVTYFFSVWAET 1853
Query 501 ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE-AVLEWDQL 542
+ G G S + + P + + L W+ +
Sbjct 1854 SAGKGELRSANVTIGPSKDGPLPPSKPQITSGQSYVTLSWNDV 1896
Score = 46.0 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 40/248 (16%), Positives = 76/248 (31%), Gaps = 51/248 (21%)
Query 126 PEKPKNLSCIVNEGKKMRCEWD-GGRETHLETNFTLKSE-WATHKFADCKAKRDTPTSCT 183
P L ++ WD + + + + + + + + ++ T +
Sbjct 1775 PGPVGVLRFSDVLMDSVKVSWDEPAQPNGMVIGYIVNYKGYRMQEEFKNEDQQRTSRNYF 1834
Query 184 VDYSTVYFVNIEVWVEAENALGK--VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
+ V V AE + GK + S ++ P K P PP + S +
Sbjct 1835 DSHGLAEGVTYFFSVWAETSAGKGELRSANVTIGP-SKDGPLPPSKPQIT---SGQSYVT 1890
Query 242 LTWTNPSIKSVIILKYNIQY----------------RTKDAS------------------ 267
L+W + S I+ + +Q R +
Sbjct 1891 LSWND-VANSDEIVGHLLQAKRVSVAEETENGYVSQRPRRNEIRGAKSAAQTSASSNSNR 1949
Query 268 ------TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
W + P D S + + ++L+P + YVFR+ G G S +E+
Sbjct 1950 PTHPIGEWITLRPTDGKSEKEQVSYRELQPSSFYVFRVFTRNVRGIGRASPETEQLFV-- 2007
Query 322 YEDRPSKA 329
E P
Sbjct 2008 PESIPDDP 2015
>sp|A2ASS6|TITIN_MOUSE Titin OS=Mus musculus OX=10090 GN=Ttn PE=1
SV=1
Length=35213
Score = 241 bits (615), Expect = 2e-64, Method: Composition-based stats.
Identities = 126/595 (21%), Positives = 202/595 (34%), Gaps = 54/595 (9%)
Query 62 ANYIVWK---TNHFTIPKEQYTIINRTASSVTF-------TDIASLNIQL-TCNILTFGQ 110
+W N P Y I R S + + ++ I+L T N F
Sbjct 29856 EKMTLWWEAPLNDGCAPVTHYIIEKRETSRLAWALIEDNCEALSYTAIKLITGNEYQFRI 29915
Query 111 LEQNVYGITI-ISGLP---------PEKPKNLSCIVNEGKKMRCEW-DGGRETH--LETN 157
N +G+ + P P+ P G + W + ++
Sbjct 29916 SAVNKFGVGRPLESDPVVAQIQYTIPDAPGVPEPSNVTGNSITLTWTRPESDGGSEIQHY 29975
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPV 217
+ E + ++ +KR + V E V AENA G + I+
Sbjct 29976 ILERREKKSTRWVKVISKRPISETRFKVTGLVEGNEYEFHVMAENAAGIGPASGISRLIK 30035
Query 218 YKVKPNPPHNLSVINSEELS-SILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPE 275
+ NPP SV+ + S + + L W P + I+ Y I+ D W ++ E
Sbjct 30036 CREPVNPPSAPSVVKVTDTSKTTVSLEWARPVFDGGMEIIGYIIEMCKADLGDWHKVNTE 30095
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
++ +TV DL+ EY FR+ + GKG S E +G AP
Sbjct 30096 PCV--KTRYTVTDLQAGEEYKFRVSAVNGAGKGD----SCEVTGTIKAVDRLSAPELDID 30149
Query 336 IDPSHTQGYRT-----VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN 390
+ T R + + ++ P A D +++ H + T N
Sbjct 30150 ANFKQTHIVRAGVSIRLFIAYQGRPTPTAVWSKPDSNLSIRA-DIHTTDSFSTLTVENCN 30208
Query 391 LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV 450
ND TLTV N GK + T+ D + K + + + W P
Sbjct 30209 -RNDAGKYTLTVENNSGK-KSITFTVKVLDSPGPPGPITFKDVTRGSATLM-WDAPLLDG 30265
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPG---- 505
I + V+ + WQ R L+ L E Y V+ G G
Sbjct 30266 GARIHHY-VIEKREASRRSWQVVSEKCTRQILKVSELTEGVPYYFRVSAENEYGVGEPYE 30324
Query 506 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG-FIRNYTIFYRTIIGN 564
PE I A + APP + + K+ AVL W L D G I +Y + R +
Sbjct 30325 MPEPIVATEQPAPPRR---LDVVDTSKSSAVLAW--LKPDHDGGSRITSYLLEMRQKGSD 30379
Query 565 ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE 619
+ +T+ L +T Y R+ A D G + P F++ + +IE
Sbjct 30380 FWVEAGHTKQLTFTVERLVENTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIE 30433
Score = 204 bits (519), Expect = 2e-52, Method: Composition-based stats.
Identities = 119/561 (21%), Positives = 190/561 (34%), Gaps = 43/561 (8%)
Query 69 TNHFTIPKEQYTIINRTASSVTFTDIASLNIQLT----CNILTFGQLEQNVYGI------ 118
+H+ I K + + ++ T S ++ +LN ++T N F + N YGI
Sbjct 26623 ISHYIIEKRETSRLSWTQVS---NEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEALES 26679
Query 119 -TIISGLP---PEKPKNLSCIVNEGKKMRCEWDGGRETH---LETNFTLKSEWATHKFAD 171
+I+ P P P M W + +E K + ++
Sbjct 26680 EPVIACNPYKRPGPPSTPEASAITKDSMVLTWTRPVDDGGAEIEGYILEKRDKEGIRWTK 26739
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-TSDHINFDPVYKV--KPNPPHNL 228
C K T V T + E V AENA G S+ F P PP N
Sbjct 26740 CNKKTLTDLRFRVTGLTEGH-SYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP 26798
Query 229 SVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
V ++ S + L W P + Y I+ + A W+ P FTV
Sbjct 26799 KVTDTSR--SSVSLAWNKPIYDGGAPVRGYVIELKKAAADEWTTCTPPSGL-QGKQFTVT 26855
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSD-WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
LK TEY FRI +G G + + E + + K+
Sbjct 26856 KLKENTEYNFRICAFNTEGVGEPATIPGSVVAQERMEAPEIELDADLRKVVTLRASATLR 26915
Query 347 VQLVWKTLPPFEANGK----ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTV 402
+ + K P E + IL + S+ N T+ D LT+
Sbjct 26916 LFVTIKGRPEPEVKWEKAEGILTERAQIEVTSSYTMLVIDNVTRF------DSGRYNLTL 26969
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD 462
N G S A + + D + + ++ KD+ + + W P I + V
Sbjct 26970 ENNSG-SKTAFVNVRVLDSPSAPVNLTIREVKKDS-VTLSWEPPLIDGGAKITNYIVEKR 27027
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+ + T+ NL E Y V G G P +K + P
Sbjct 27028 ETTRKAYATITNNCTKNTFKIENLQEGCSYYFRVLASNEYGIGLPAETAEPVKVSEPPLP 27087
Query 523 PT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS 581
P V V +N A ++W++ P I Y + +T + + E T+S
Sbjct 27088 PGRVTLVDVTRNTATIKWEK-PESDGGSKITGYVVEMQTKGSEKWSACTQVKTLETTISG 27146
Query 582 LTSDTLYMVRMAAYTDEGGKD 602
LT+ Y+ R+AA ++G D
Sbjct 27147 LTAGEEYVFRVAAVNEKGRSD 27167
Score = 198 bits (504), Expect = 1e-50, Method: Composition-based stats.
Identities = 121/582 (21%), Positives = 198/582 (34%), Gaps = 33/582 (6%)
Query 43 NFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTA-SSVTFTDIASLNIQL 101
V EKC + +H+ + K + + + T +S T+ + L
Sbjct 25514 PVQVTGVTAEKCTLAWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLL 25573
Query 102 TCNILTFGQLEQNVYGI-------TIISGLP---PEKPKNLSCIVNEGKKMRCEWD-GGR 150
N F + N YG+ ++ P P PK+L M W+
Sbjct 25574 EGNKYIFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDS 25633
Query 151 ETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
+ E K + + ++ C +R T V T E V AENA G
Sbjct 25634 DGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDH-EYEFRVSAENAAGVGE 25692
Query 209 SDH--INFDPVYKV-KPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTK 264
+ + V KP PP N V+++ + S + L W+ P IL Y ++
Sbjct 25693 PSPATVYYKACDPVFKPGPPTNAHVVDTTKNS--ITLAWSKPIYDGGSEILGYVVEICKA 25750
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW-SDWSEEASGITYE 323
D W + P+ T + F + L EY R+ + + G G S E
Sbjct 25751 DEEEWQIVTPQ-TGLRVTRFEIAKLIEHQEYKIRVCALNKVGLGEAASVPGTVKPEDKLE 25809
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN 383
S K G + + +K P E I + +N
Sbjct 25810 APELDLDSELRKGIVVRAGGSARIHIPFKGRPTPE----ITWSKEEGEFTDKVQIEKGIN 25865
Query 384 ATKLTVNL--TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
T+L+++ ND L + N G S +A +T+ D + +K KD++L V
Sbjct 25866 FTQLSIDNCDRNDAGKYILKLENSSG-SKSAFVTVKVLDTPGPPQNLAVKEVRKDSVLLV 25924
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
W P + + + ++ ++ NL E Y V
Sbjct 25925 -WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCNKTSFRVENLTEGAIYYFRVMAENE 25983
Query 502 DGPGSP-ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G G P E+ A PPS V V + A L W++ P I Y + +
Sbjct 25984 FGVGVPTETSDAVKASEPPSPPGKVTLTDVSQTSASLMWEK-PEHDGGSRILGYVVEMQP 26042
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ +V +S +S L+S Y R+ AY ++G D
Sbjct 26043 KGTEKWSVVAESKVCNAVVSGLSSGQEYQFRVKAYNEKGKSD 26084
Score = 193 bits (489), Expect = 1e-48, Method: Composition-based stats.
Identities = 114/603 (19%), Positives = 190/603 (32%), Gaps = 68/603 (11%)
Query 75 PKEQYTIINRTASSVTFTDIASLNIQLT---------CNILTFGQLEQNVYGI------- 118
+ Y + R S + +T++ + +Q+T N F + N YG+
Sbjct 23375 KIDHYIVQKRETSRLAWTNV-ATEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 23433
Query 119 -TIISGL--PPEKPKNLSCIVNEGKKMR-CEWDGGRETHLE--TNFTLKSEWATHKFADC 172
+ PP+ PKN M C + E + + A ++ C
Sbjct 23434 PVLAVDPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWVKC 23493
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG-KVTS--DHINFDPVYKVKPNPPHNLS 229
K T V T E + AENA G S KP PP N
Sbjct 23494 NKKALTDLRFKVSGLTEGH-EYEFRIMAENAAGISAPSATSPFYKACDTVFKPGPPGNPR 23552
Query 230 VINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
V+++ S + + W P I Y ++ + W + P +S+T+
Sbjct 23553 VLDTSR--SSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQVVTP-PAGLKATSYTITS 23609
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR--- 345
L EY RI M +G G G + P D R
Sbjct 23610 LIENQEYKIRIYAMNSEGLGEP----ALVPGTPKAEERMLPPEIELDADLRKVVTIRACC 23665
Query 346 TVQLV--WKTLPPFEANGKILDYEVTLTRWKSHLQN--YTVNATKLTVNLTN-----DRY 396
T++L K P E V R + + + T+ + D
Sbjct 23666 TLRLFVPIKGRPAPE---------VKWAREHGESLDKASIESTSSYTLLVVGNVNRFDSG 23716
Query 397 LATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
LTV N G S +A + + D + +K + + W P I
Sbjct 23717 KYILTVENSSG-SKSAFVNVRVLDTPGPPQNLKIKEV-TKTSVTLTWEPPLLDGGSKIKN 23774
Query 457 WCVLSDKAPCITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVYADGPGSP-ESIKAYL 514
+ ++ + + H+T + L E Y V G G P E+ ++
Sbjct 23775 Y-IVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVK 23833
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH 574
P + V +N L W++ P I Y + ++ + A
Sbjct 23834 ASERPLPPGKITLTDVTRNSVSLSWEK-PEHDGGSRILGYIVEMQSKGSDRWATCATVKV 23892
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTL 634
TE T++ L Y R++A ++G D + P A+ +V+P L T
Sbjct 23893 TEATITGLIQGEEYSFRVSAQNEKGISD--PRQLSVPVIAKD----LVIPPAFKLLFNTF 23946
Query 635 LGV 637
+
Sbjct 23947 TVL 23949
Score = 191 bits (485), Expect = 3e-48, Method: Composition-based stats.
Identities = 107/577 (19%), Positives = 183/577 (32%), Gaps = 52/577 (9%)
Query 68 KTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCN-ILTFGQLEQNVYGI-------T 119
K ++ + ++ S T D +LT N F +N+YG+
Sbjct 15603 KITNYVVERKATDSDVWHKLSSTVKDTNFKATKLTPNKEYIFRVAAENMYGVGEPVQAAP 15662
Query 120 IISGL---PPEKPKNLSCIVNEGKKMRCEW-DGGRETHLE-TNF-TLKSEWATHKFADCK 173
II+ PP P L + W + + T + + + T K+ C
Sbjct 15663 IIAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCN 15722
Query 174 AKRDTPTSCTVDYSTVYFVNIEVWVEAENALG----KVTSDHINFDPVYKVKPNPPHNLS 229
K + V AEN G +++ I P PP +
Sbjct 15723 -KMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSRSTEPILIKD-PIDPPWPPGKPT 15780
Query 230 VINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
V + + L L WT P I Y I+ W ++ + +
Sbjct 15781 VKDIG--KTSLVLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAE---GVPTTEHLLTG 15835
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
L EY FR+R + + G+ S+ S+ PS P W ++ T
Sbjct 15836 LMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPS--PPRWLEVI---NITKNTAD 15890
Query 349 LVWKTLPPFEANGKILDYEVT---LTRWKSHLQNYTVNATKLTVNLTNDR--YLATLTVR 403
L W T+P + I +Y V + R + TV TK TV + Y+ +
Sbjct 15891 LKW-TVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAE 15949
Query 404 NLVGKSDAAVL---TIPACDFQATHPVMDLKAFPKDNM-LWVEWTTPRESVKKYILEWCV 459
N +G+SD + + F P L + ++W P+ + I + +
Sbjct 15950 NAIGQSDYTEIGDSVLAKDTFTTPGPPYALTVVDVTKRHVDLKWEPPKNDGGRPIQRY-I 16008
Query 460 LSDKAPCITDWQQEDGTVHR--TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL--- 514
+ K T W + T + ++ E V G G P L
Sbjct 16009 IEKKEKLGTRWVKAGKTSGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIE 16068
Query 515 -KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNV-D 571
+PPS + G+ + W P I Y + + VN
Sbjct 16069 DPTSPPSPPLDLHVTDAGRKHIAIAWKP-PEKNGGSPIIGYHVEMCPVGTEKWMRVNSRP 16127
Query 572 SSHTEYTL-SSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
++ + + D Y++R+ A G + E +
Sbjct 16128 IKDLKFKVEEGIVPDKEYVLRVRAVNAVGVSEPSEIS 16164
Score = 186 bits (473), Expect = 1e-46, Method: Composition-based stats.
Identities = 111/669 (17%), Positives = 211/669 (32%), Gaps = 50/669 (7%)
Query 41 HSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTD-IASLNI 99
V EK + A+ K H+ + K + + + + + + I +
Sbjct 28759 GGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVAENLEECIVTTTK 28818
Query 100 QLTCNILTFGQLEQNVYGIT----------IISGLPPEKPKNLSCIVNEGKKMRCEWDGG 149
+ N F N YGI + + P P M WD
Sbjct 28819 IIKGNEYVFRVRAVNKYGIGEPLESEPVVAKNAFVTPGPPSIPEVTKITKNSMTVVWDRP 28878
Query 150 RETH---LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK 206
+ F + + + + + T V T + + V A NA G
Sbjct 28879 TVDGGSEINGYFLERRDKKSLAWLKVLKETIRDTRQKVTGLTE-NSDYQYRVCAVNAAGV 28937
Query 207 VT-SDHINF--DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYR 262
S+ +F P PP + + ++ S + L W+ P + Y ++ +
Sbjct 28938 GPFSEPSDFYKAADPIDPPGPPAKIRI--ADSTKSSITLGWSKPVYDGGSDVTGYVVEMK 28995
Query 263 TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
D W+ + T + + V +LKP Y F++ + G+G +E A
Sbjct 28996 QGDEEEWTIVSTRGEVRT-TEYVVSNLKPGVNYYFQVSAVNCAGQGEPITMTEPAQAKDV 29054
Query 323 EDRPSKAPSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
+ P + G + + +K PP + + + S +
Sbjct 29055 LEEPEIDLDVALRTSVIAKAGEDVQLLIPFKGRPPPTVTWRKDEKNLGSDTRYSIQNTDS 29114
Query 382 VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
+ + ND LT+ N VG+ ++ +++ D A + +K + +
Sbjct 29115 SSLLVIPQVTRNDTGKYILTIENGVGQPKSSTVSVKVLDTPAACQKLQVKHVSLGTVTLL 29174
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVY 500
W P I+ + + A T W T + +L+E + V
Sbjct 29175 -WDPPLIDGGSPIINYVIEKRDATKRT-WSVVSHKCSGTSFKVTDLSEKTPFFFRVLAEN 29232
Query 501 ADGPGSP-ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
G G P E+ + P+ + K K VL W + D I +Y + +
Sbjct 29233 EIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVVLSWTKPDFD-GGSIITDYLVERK 29291
Query 560 TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD----GP---EFTFTTPK 612
+ S E + L ++ R++A ++G D GP + TP+
Sbjct 29292 GKGEQAWSHAGISKTCEIEIGQLKEQSVLEFRVSARNEKGQSDPVTIGPLTVKELVITPE 29351
Query 613 FAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPP 672
EI + V + ++ + + P PS S + P
Sbjct 29352 VDLSEIPGAQISVRIGH---------------NVHLELPYKGKPKPSISWLKDGLPLKES 29396
Query 673 RHNFNSKDQ 681
+ SK +
Sbjct 29397 EYVRFSKTE 29405
Score = 185 bits (468), Expect = 3e-46, Method: Composition-based stats.
Identities = 106/577 (18%), Positives = 185/577 (32%), Gaps = 60/577 (10%)
Query 65 IVWK--TNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNI--------LTFGQLEQN 114
I WK + Y I + + + S + + TC + F +N
Sbjct 18720 ISWKPPLDDGGSEITNYIIEKKELGKDIWMPVTSASAKTTCKVPKLLEGKDYIFRIHAEN 18779
Query 115 VYGI--TIISGL--------PPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTL-KS 162
+YGI ++S P+ P+ W+ + TN+ L K
Sbjct 18780 LYGISDPLVSDSMKAKDRFRVPDAPEQPVVTEVTKDSALVTWNKPNDGGKPITNYILEKR 18839
Query 163 EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN---FDPVYK 219
E + ++ + P + + E V AEN +G + F
Sbjct 18840 ETMSKRWVRVTKEPIHPYTKYRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFARDPI 18899
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
KP+PP N I++ S ++LTW P IL Y ++Y+ W + +
Sbjct 18900 AKPSPPINPEAIDTTCNS--VELTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 18957
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS----FWY 334
+ + V L+ Y FR+ + E G+ + E + P
Sbjct 18958 CPETKYKVTGLRDGQSYKFRVLAVNEAGESDPAHVPEPVLVKDRLEPPELILDANMAREQ 19017
Query 335 KIDPSHTQGYRTVQ-------LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKL 387
I T + + WK E ++ +T S L+
Sbjct 19018 HIRVGDTLRLSAIIKGVPFPKVTWK----KEDREAPTKAQIDVTPVGSKLEIRNAAH--- 19070
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
D + +LTV N G +V + D +++ KD+ ++ W P
Sbjct 19071 -----EDGGIYSLTVENPAGTKTVSVKVL-VLDKPGPPRDLEVSEIRKDSC-YLTWKEPL 19123
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGT-VHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ + + V+ K W T ++++ +L E YL V G G
Sbjct 19124 DDGGSVVTNY-VVERKDVATAQWSPLSTTSKKKSHMAKHLTEGNQYLFRVAAENQYGRGP 19182
Query 507 ----PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII 562
P+ IKA PP + V K E L W++ P I Y + Y+
Sbjct 19183 FVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNK-PDRDGGSPITGYLVEYQEEG 19241
Query 563 GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ + + ++ L Y R+ A G
Sbjct 19242 DKDWIKFKTVKNLDCVVTGLQQGKTYRFRVKAENIIG 19278
Score = 183 bits (464), Expect = 1e-45, Method: Composition-based stats.
Identities = 93/569 (16%), Positives = 175/569 (31%), Gaps = 40/569 (7%)
Query 57 YFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNI---QLTCNILTFGQLEQ 113
Y I W + + ++ T I T +++ + + + +
Sbjct 18631 YSGKPKPKIDWFKDEADVLEDDRTHIKTTPTTLALEKTKAKRSDSGKYCVVVENSTGSRK 18690
Query 114 NVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFAD 171
+ + P + + M W + TN+ ++ +
Sbjct 18691 GFCQVNV-VDRPGPPVGPVIFDEVTKEYMVISWKPPLDDGGSEITNYIIEKKELGKDIWM 18749
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT---SDHINFDPVYKVKPNPPHNL 228
T+C V + + AEN G SD + ++V P+ P
Sbjct 18750 PVTSASAKTTCKVPKLLEGK-DYIFRIHAENLYGISDPLVSDSMKAKDRFRV-PDAPEQP 18807
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
V +E +TW P+ I Y ++ R + W ++ E + + V D
Sbjct 18808 VV--TEVTKDSALVTWNKPNDGGKPITNYILEKRETMSKRWVRVTKEPI-HPYTKYRVPD 18864
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
L +Y FR+ E G G S S+ +PS + + +V+
Sbjct 18865 LLEGCQYEFRVSAENEIGIGDPSPPSKPVFARDPIAKPSPPINPEAIDTTCN-----SVE 18919
Query 349 LVWKTLPPFEANGKILDYEVTL--------TRWKSHLQNYTVNATKLTVNLTNDRYLATL 400
L W+ P + KIL Y V R ++ K+T Y +
Sbjct 18920 LTWQP-PRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQSYKFRV 18978
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDL--KAFPKDNMLWVEWTTPRESVKKYI---- 454
N G+SD A + P P + ++ + V T ++ K +
Sbjct 18979 LAVNEAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIRVGDTLRLSAIIKGVPFPK 19038
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+ W +AP + Y +TV G + L
Sbjct 19039 VTWKKEDREAPTKAQIDVTPVGSKLEIRNAAHEDGGIYSLTVE--NPAGTKTVSVKVLVL 19096
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDSS 573
+ P + ++ K+ L W + P+D + NY + + + + ++ S
Sbjct 19097 DK--PGPPRDLEVSEIRKDSCYLTWKE-PLDDGGSVVTNYVVERKDVATAQWSPLSTTSK 19153
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ LT Y+ R+AA G
Sbjct 19154 KKSHMAKHLTEGNQYLFRVAAENQYGRGP 19182
Score = 180 bits (456), Expect = 1e-44, Method: Composition-based stats.
Identities = 97/518 (19%), Positives = 165/518 (32%), Gaps = 53/518 (10%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHKFADCKAK 175
I + PP PK L + W+ + T + ++ + K
Sbjct 15269 INVNVIAPPSAPKELKFSDITKDSVHLTWEPPDDDGGSPLTGYVVEKRDMSRKTWTKVMD 15328
Query 176 RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS----DHINFDPVYKVKPNPPHNLSVI 231
T TV V V A N G + +N V P+PP N V
Sbjct 15329 FVTDLEFTVP-DLVQGKEYLFKVCARNKCGPGEPAYTDEPVNMSAPATV-PDPPEN--VK 15384
Query 232 NSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ ++ + LTW P + I Y ++ + + W E T+ V L+
Sbjct 15385 WRDRTANSIFLTWDPPKNDGGSRIKGYIVEKCPRGSDKWVA-CGEPVPDTKME--VTGLE 15441
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR---TV 347
Y +R++ + G S +EE + ++ P + G +
Sbjct 15442 EGKWYAYRVKALNRQGASKPSKPTEEIQAVDTQEAPEIFLDVKLLAGITVKAGTKIELPA 15501
Query 348 QLVWKTLPPFEANGKILDYEVTLTRWKS--------HLQNYTVNATKLTVNL-TNDRYLA 398
+ K P +T T+ + ++N +T + +D
Sbjct 15502 TVTGKPEPK-----------ITWTKADTLLKPDQRITIENVPKKSTVTITDSKRSDTGTY 15550
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWC 458
+ N+ G+ AV+ + D D+ ++ L + W PR+ I +
Sbjct 15551 IIEAVNVCGR-ATAVVEVNVLDKPGPPAAFDITDVTNESCL-LTWNPPRDDGGSKITNY- 15607
Query 459 VLSDKAPCITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVYADGPGSP---ESIKAYL 514
V+ KA W + TV T + L +K Y+ V G G P I A
Sbjct 15608 VVERKATDSDVWHKLSSTVKDTNFKATKLTPNKEYIFRVAAENMYGVGEPVQAAPIIAKY 15667
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV---- 570
+ PP + + K+ L W + P D I Y + + +T V
Sbjct 15668 QFDPPGPPTRLEPSDITKDAVTLTWCE-PDDDGGSPITGY---WVERLDPDTDKWVRCNK 15723
Query 571 -DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
T Y + LT+ Y R+ A G T
Sbjct 15724 MPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSRST 15761
Score = 179 bits (454), Expect = 2e-44, Method: Composition-based stats.
Identities = 95/550 (17%), Positives = 172/550 (31%), Gaps = 23/550 (4%)
Query 59 HVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGI 118
+ W+ + + + + + + ++ + N+ +
Sbjct 26922 GRPEPEVKWEKAEGILTERAQIEVTSSYTMLVIDNVTRFDSGRY-NLTLENNSGSKTAFV 26980
Query 119 TIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKR 176
+ P P NL+ + + W+ TN+ ++ T K
Sbjct 26981 NVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNN 27040
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
T + ++ V A N G P PP +++++
Sbjct 27041 CTKNTFKIENLQEGCSYY-FRVLASNEYGIGLPAETAEPVKVSEPPLPPGRVTLVDVTRN 27099
Query 237 SSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
++ +K W P S I Y ++ +TK + WS T T T+ L EY
Sbjct 27100 TATIK--WEKPESDGGSKITGYVVEMQTKGSEKWSACTQVKTLET----TISGLTAGEEY 27153
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
VFR+ + E G+ E +PS F ++ Q + + +K P
Sbjct 27154 VFRVAAVNEKGRSDPRQLGVPVIAKDIEIKPSVELPFNTFNVKANDQLK--IDIPFKGRP 27211
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT 415
K + T + + TV + D L V N G +
Sbjct 27212 QATVAWKKDGQVLRETTRVNVASSKTVTTLSIKEASREDVGTYELCVSNTAGSITVPITV 27271
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
I D + + DN + + W P I + ++ + T WQ
Sbjct 27272 I-VLDRPGPPGPIRIDEVSCDN-VSISWNPPEYDGGCQISNY-IVEKRETTSTTWQVVSQ 27328
Query 476 TVHRTYLR-GNLAESKCYLITVTPVYADGPGSPESIKAYLKQ---APPSKGPTVRTKKVG 531
V RT ++ L Y V G S A + + +PP T +
Sbjct 27329 AVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHAT 27388
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG--NETAVNVDSSHTEYTLSSLTSDTLYM 589
K+ V+ W Q+PV+ + Y + Y+ A V + T+ +S L +Y
Sbjct 27389 KSTMVVSW-QVPVNDGGSQVIGYHLEYKERSSILWSKANKVLIADTQMKVSGLDEGLMYE 27447
Query 590 VRMAAYTDEG 599
R+ A G
Sbjct 27448 YRVYAENIAG 27457
Score = 178 bits (451), Expect = 4e-44, Method: Composition-based stats.
Identities = 107/576 (19%), Positives = 168/576 (29%), Gaps = 70/576 (12%)
Query 70 NHFTIPKEQYTIINRTASSVTFTDIASLNIQLT--------CNILTFGQLEQNVYGIT-- 119
N +P Y + R S T+ ++A+ I+ T F QN YG+
Sbjct 22974 NDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGVEYQFRVRAQNRYGVGPG 23033
Query 120 -----IISGLP---PEKPKNLSCIVNEGKKMRCEWD-GGRETHLE-TNFTLKSEWATHKF 169
+++ P P P M W + + ++ +
Sbjct 23034 ITSASVVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHIERKERNGIL 23093
Query 170 ADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN---FDPVYKVKPNPPH 226
+K P + + E V AEN GK + F P P
Sbjct 23094 WQTVSKALVPGNIFKSTGLTDGIAYEFRVIAENMAGKSKPSKPSEPMFALDPIDPPGKPV 23153
Query 227 NLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
L++ + L W P I Y ++ R W + + + FT
Sbjct 23154 PLNITRH-----TVALKWAKPEYTGGFKITSYVVEKRDLPNGRWLKANFSNIL--ENEFT 23206
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT---- 341
V L Y FR+ G S SE + IT D +AP + T
Sbjct 23207 VSGLTEDAAYEFRVIAKNAA--GAISPPSEPSDAITCRD-DLEAPRIMVDVRFKDTITLK 23263
Query 342 -----------QGYRTVQLVW-KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV 389
G + W K E GK+ E+ + + +HL N + T
Sbjct 23264 AGEAFKLEADVSGRPPPTMEWTKDGKELEGTGKL---EIKIADFSTHLINKDSSRT---- 23316
Query 390 NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES 449
D LT N G + + + + + + W P +
Sbjct 23317 ----DSGAYILTATNPGGFAKHIFNVKVLDRPGPPEGPLAVSDVTSEKCV-LSWLPPLDD 23371
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPGSP- 507
I + V + + W V T L+ L + Y+ V V G G P
Sbjct 23372 GGAKIDHYIVQKRETSRLA-WTNVATEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPL 23430
Query 508 --ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE 565
E + A PP + K+ V+ W P I NY + R G
Sbjct 23431 ESEPVLAVDPYGPPDPPKNPEVTTITKDSMVVCWGH-PDSDGGSEIINYIVERRDKAGQR 23489
Query 566 --TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ + +S LT Y R+ A G
Sbjct 23490 WVKCNKKALTDLRFKVSGLTEGHEYEFRIMAENAAG 23525
Score = 176 bits (446), Expect = 2e-43, Method: Composition-based stats.
Identities = 105/611 (17%), Positives = 193/611 (32%), Gaps = 56/611 (9%)
Query 27 PCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTA 86
C + P + EKC + +++ + K + + + T
Sbjct 27665 NCKVLDKPGP--PAG-PLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSRLAWTI 27721
Query 87 SSVTFTDIASLNIQLT----CNILTFGQLEQNVYGIT-------IISGLP---PEKPKNL 132
++ + + ++T N F N YG+ + + P P P +L
Sbjct 27722 CE---AELRTTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESMAVKALDPFTTPSPPTSL 27778
Query 133 SCIVNEGKKMRCEWDGGRETH---LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
M W + + E + ++ K
Sbjct 27779 EITSVTKDSMTLCWSRPETDGGSDISGYIIERREKNSLRWMRVNKKPVYDLRVKSTGLRE 27838
Query 190 YFVNIEVWVEAENALG-KVTS--DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
E V AENA G + S + P+PP +++S + + + W
Sbjct 27839 G-CEYEYRVFAENAAGLSLPSETSPLVRAEDPVFLPSPPSKPKIVDSG--KTTITIGWVK 27895
Query 247 PSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P I Y ++Y+ + + W ++ + T +T+ L EYVFR+R + +
Sbjct 27896 PLFDGGAPITGYTVEYKKSEETDW-KVAIQSFRGT--EYTMSGLTTGDEYVFRVRSLNKM 27952
Query 306 GKGYWSDWSEEASGITYEDRPS-KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
G SD S+ E+ P S K T+ + ++ P +
Sbjct 27953 GASDPSDSSDPQVAKEREEEPVFDVDSEMRKTLIVKAGSSFTMTVPFRGRPIPNVSWSKP 28012
Query 365 DYEVTLTRWKSHLQNYTVNATKLTVNL--TNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
D ++ + + T + T LT+ ND TLT++N++ + + D
Sbjct 28013 DTDLRTRAYI----DSTDSRTLLTIENANRNDSGKYTLTIQNVLSA-ASMTFVVKVLDSP 28067
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR-TY 481
+ ++ K+ + + W P + + + +A W +R +Y
Sbjct 28068 GPPANITVREVTKETAM-LSWDVPENDGGAPVKNYHIEKREA-SKKAWVSVTNNCNRLSY 28125
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP-----PSKGPTVRTKKVGKNEAV 536
NL E Y V+ G G P K+ PS + V K+
Sbjct 28126 KVTNLQEGAIYYFRVSGENEFGVGVPAE----TKEGVKITEKPSPPEKLGVTSVSKDSVS 28181
Query 537 LEWDQLPVDVQNG-FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
L W L + G I +Y + T + +S L Y R+ A
Sbjct 28182 LSW--LKPEHDGGSRIIHYVVEALEKGQKTWVKCAVVKTTHHVVSGLRESHEYFFRVFAE 28239
Query 596 TDEGGKDGPEF 606
G D E
Sbjct 28240 NQAGLSDPREL 28250
Score = 174 bits (441), Expect = 7e-43, Method: Composition-based stats.
Identities = 120/657 (18%), Positives = 211/657 (32%), Gaps = 67/657 (10%)
Query 69 TNHFTIPKEQYTIINRTASSVTFTDIASLNIQLT----CNILTFGQLEQNVYGITII-SG 123
++ + K + + + S ++ + + +T N F +N G
Sbjct 20117 IQNYILEKCESKRMVWSTYS---ANVLTPSATVTRLIEGNEYIFRVRAENKIGTGPPTES 20173
Query 124 LP---------PEKPKNLSCIVNEGKKMRCEWDGGRETH---LETNFTLKSEWATHKFAD 171
P P +P ++M W+ + + K E ++
Sbjct 20174 KPVIAKTKYDRPGRPDPPEVTKVSKEEMTVVWNAPEYDGGKSITGYYLEKKEKHAVRWVP 20233
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG----KVTSDHINFDPVYKVKPNPPHN 227
K P + + + V+AEN +G + S + P PP N
Sbjct 20234 -VNKSAIPERRLKVQNLLPGHEYQFRVKAENEVGIGEPSLPSRPV-VAKDPIEPPGPPTN 20291
Query 228 LSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYRTK--DASTWSQIPPEDTAST--RS 282
V+++ S + L W P I+ Y ++ R K DAS + A+ R
Sbjct 20292 FKVVDT--TKSSITLAWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLIRM 20349
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
FTV L EY FR+ + G G ++ E + P +
Sbjct 20350 EFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDA-SMRKLVVVR 20408
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN---DRYLAT 399
++L + K+ +V + Q V+ V + D +
Sbjct 20409 AGCPIRLF--AIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYS 20466
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
LT+ N G+ A + + D + + K + V W P + + V
Sbjct 20467 LTLVNPAGE-KAVFVNVKVLDTPGPVADLKVSDVTKTSC-HVSWAPPENDGGSQVTHYIV 20524
Query 460 LSDKAPCITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVYADGPGS----PESIKAYL 514
+A T W V +T + NL Y VT V GPG P+ + A
Sbjct 20525 EKREAERKT-WSTVTPEVKKTSFNVTNLVPGNEYFFRVTAVNEYGPGVPTDIPKPVLASD 20583
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG---NETAVNVD 571
+ P + ++ KN A L W P+ I Y I YR T +V
Sbjct 20584 PLSEPDPPRKLEVTEMTKNSATLAWLP-PLRDGGAKIDGYIISYREEDQPADRWTEYSV- 20641
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLL 631
++ L Y R+AA G + P+ A+G EA + L+
Sbjct 20642 VKDLSLIVTGLKEGKKYKFRVAARNAVG--------VSMPREAEGVYEAKEQLLPPKILM 20693
Query 632 TTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNF 688
+ + K+ ++ H++ P+P I +W + +DG+
Sbjct 20694 PEQITIKAG--KKLRVEAHVYGK-PNP----ICKWKKGDDEVVTSSHLAIHKADGSS 20743
Score = 173 bits (438), Expect = 1e-42, Method: Composition-based stats.
Identities = 113/598 (19%), Positives = 192/598 (32%), Gaps = 65/598 (11%)
Query 43 NFTAVCVLKEKCMDYFHVNANYIVWK--TNHFTIPKEQYTIINRTASSVTFTDIASLNIQ 100
V EKC + WK Y + R S + +T + +
Sbjct 24432 PVAISGVTAEKCT---------LAWKPPLQDGGSDITNYIVERRETSRLVWTLVDANVQT 24482
Query 101 LTC--------NILTFGQLEQNVYGIT-------IISGLP---PEKPKNLSCIVNEGKKM 142
L+C N F + N YG+ +I+ P P+ PK M
Sbjct 24483 LSCKVLKLLEGNEYIFRIMAVNKYGVGEPLESESLIAKNPFVVPDAPKAPEVTAVTKDSM 24542
Query 143 RCEWDGGRETH---LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
W+ + K + ++ C + V N E V
Sbjct 24543 IVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLLENH-NYEFRVS 24601
Query 200 AENALGKVTSDHINF-----DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI- 253
AENA G + DP+Y KP PP+N V++ S + L+WT P
Sbjct 24602 AENAAGLSEPSPPSAYQKACDPIY--KPGPPNNPKVMDVTR--SSVFLSWTKPIYDGGCE 24657
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
I Y ++ W+ P T +++ V+ L EY FRI + + G G +D
Sbjct 24658 IQGYIVEKCDVSVGEWTMCTP-PTGINKTNLEVEKLLEKHEYNFRICAINKAGVGEHADV 24716
Query 314 SEEASGITYEDRPSKAPSFW-YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR 372
+ P K+ G + + K P E V +
Sbjct 24717 PGPVMVEEKLEAPDIDLDLELRKVINIRAGGSLRLFVPIKGRPTPE---------VKWGK 24767
Query 373 WKSHLQNYTVN--ATKLTVNLT-----NDRYLATLTVRNLVGKSDAAVLTIPACDFQATH 425
+++ + + T + D TLT+ N G +A +T+ D +
Sbjct 24768 VDGDIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGT-KSAFVTVRVLDTPSPP 24826
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+ + KD+ + + W P I + V +A + ++
Sbjct 24827 VNLKVTEITKDS-VSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQ 24885
Query 486 LAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPV 544
L E Y VT G G P +K A + P + V +N L W + P
Sbjct 24886 LQEGCSYYFRVTAENEYGIGLPARTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK-PE 24944
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
I Y + + ++ + + +++LT Y+ R+ A ++G D
Sbjct 24945 HDGGSKIIQYIVEMQAKNTDKWSECARVKSLDAVITNLTQGEEYLFRVIAVNEKGRSD 25002
Score = 170 bits (431), Expect = 1e-41, Method: Composition-based stats.
Identities = 107/614 (17%), Positives = 199/614 (32%), Gaps = 56/614 (9%)
Query 44 FTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTC 103
T V +EKC + + + H+ + + + + +N V + + +
Sbjct 30936 LTVSRVTEEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVI--VEGECLTASYVVTRL 30993
Query 104 ---NILTFGQLEQNVYGITIIS-GLP---------PEKPKNLSCIVNEGKKMRCEW-DGG 149
N TF N YG+ + P P +P + + + +W
Sbjct 30994 IKNNEYTFRVRAVNKYGLGVPVESEPIVARNSFTIPSQPGIPEEVGAGKEHIIIQWTKPE 31053
Query 150 RETHLE-TNFTL-KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV 207
+ E +N+ + K E + ++ + S + + + V A NA G
Sbjct 31054 SDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNS 31113
Query 208 TSDHINFDPVYKVK---PNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRT 263
+ + P PP V+++ + L WT P I+ Y ++ +
Sbjct 31114 EPSEASNFISCREPSYTPGPPSAPRVVDT--TKRSISLAWTKPMYDGGTDIIGYVLEMQE 31171
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
KD W ++ + + FTV DLK +Y FR+ + G +S+ + E +
Sbjct 31172 KDTDQWCRV-HTNATIRNNEFTVPDLKMGQKYSFRVAAVNAKGMSDYSETTAEIEPVERL 31230
Query 324 DRPSKAPSFWYKIDP-----------SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR 372
+ P + K G + + W AN I+D
Sbjct 31231 EIPDLELADDLKKTVIVRAGASLRLMVSVSGRPSPVITWSKKGIDLANRAIID------N 31284
Query 373 WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA 432
+S+ + D T+ N GK +A + + D P + +K
Sbjct 31285 TESYSLLIVDKVNR------YDAGKYTIEAENQSGK-KSATVLVKVYDTPGPCPSVSVKE 31337
Query 433 FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
+D+ + + W P + + + +A Y L E Y
Sbjct 31338 VSRDS-VTITWEIPTIDGGAPVNNYIIEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMY 31396
Query 493 LITVTPVYADGPGSP-ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
V P G G P E+ A L P + V K+ L W++ P+ +
Sbjct 31397 YFRVLPENIYGIGEPCETSDAVLVSEVPLVPTKLEVVDVTKSTVTLAWEK-PLYDGGSRL 31455
Query 552 RNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT 609
Y + V + + E+T+ SL Y+ R+ A ++G + P
Sbjct 31456 TGYVLEACKAGTERWMKVVTLKPTVLEHTVISLNEGEQYLFRVRAQNEKGVSE-PRE-IV 31513
Query 610 TPKFAQGEIEAIVV 623
TP Q +
Sbjct 31514 TPVTVQDLRVLPTI 31527
Score = 170 bits (430), Expect = 1e-41, Method: Composition-based stats.
Identities = 106/645 (16%), Positives = 188/645 (29%), Gaps = 59/645 (9%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P P F + + C +H+ ++ + K + + + + T
Sbjct 20783 PPQP------PFDISEIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVT 20836
Query 93 DIA-SLNIQLTCNILTFGQLEQNVYGITIISGLP----------PEKPKNLSCIVNEGKK 141
+ + + F +N +GI+ P P +PKN
Sbjct 20837 KTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMLAKFPFDVPSEPKNARVTKVNKDC 20896
Query 142 MRCEWD-GGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
+ WD + T + ++ + ++ V + +
Sbjct 20897 IFVAWDRPDSDGGSPITGYLIERKERNSLLWVKANDTIVRSTEYPCAGLVEGLEYSFRIY 20956
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYN 258
A N G ++ +PP V++ + S+ L W P I+ Y
Sbjct 20957 ALNKAGSSPPSKPTEYVTARMPVDPPGKPEVVDVTKNSAS--LIWARPKHDGGSRIIGYF 21014
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
++ W + + +T L+ +Y FR S+ S+ +
Sbjct 21015 VEACKLPGDKWVRCNTTPHQIPQEEYTATGLEENAQYQFRAIAKTAVNISQPSEPSDPVT 21074
Query 319 GITYEDRPSKAPSFWYK--------IDPS---HTQGYRTVQLVWK--TLPPFEANGKILD 365
+ P S K + G + WK T P +A G
Sbjct 21075 ILAENVPPRIELSVEMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDTTPIKQAEGI--- 21131
Query 366 YEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATH 425
++ + R L+ ++VN D T+T N G S +A + + D
Sbjct 21132 -KMAMKRNLCTLELFSVN--------RKDSGDYTITAENSSG-SKSATIKLKVLDKPGPP 21181
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH-RTYLRG 484
+ + D + + W P E I + ++ + +W Q TV +
Sbjct 21182 ASVKINKMYADRAM-LSWEPPLEDGGSEITNY-IIDKRETSRPNWAQVSATVPITSCTVE 21239
Query 485 NLAESKCYLITVTPVYADGPGSP---ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
L E Y + G G P E A PP + + K+ + W
Sbjct 21240 KLIEGHEYQFRICAENKYGVGDPILTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKA 21299
Query 542 LPVDVQNGFIRNYTIFYRTIIG-NETAVN-VDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
P D I Y + R N T VN + L T Y R+ A G
Sbjct 21300 -PADDGGSPITGYLVEKRETQAVNWTKVNRKPVIERTLKATGLQEGTEYEFRVTAINKAG 21358
Query 600 GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
G + +AQ + P TT V + K
Sbjct 21359 --PGKPSDASKAVYAQDPLYPPGPPAFPKVYDTTRSSVSLSWGKP 21401
Score = 170 bits (429), Expect = 2e-41, Method: Composition-based stats.
Identities = 113/619 (18%), Positives = 187/619 (30%), Gaps = 41/619 (7%)
Query 18 TESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKE 77
T S G + I E P + V + + + A + +++ + K
Sbjct 26176 TNSAGTATENLSVIVLEKPGPPVG-PVKFDEVSADFVVISWEPPAYTGGCQISNYIVEKR 26234
Query 78 QYTIINRTASSVTFTDIASLNIQL-TCNILTFGQLEQNVYGI-------TIISGLP---P 126
T N S T +L T F +N YG ++ P P
Sbjct 26235 DTTTTNWQMVSATVARTTIKISKLKTGTEYQFRIFAENRYGKSTPLDSKPVVVQYPFKEP 26294
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P +M +W T + L+ + K +
Sbjct 26295 GPPGTPFVTSISKDQMLVQWHEPVNDGGSKVTGYHLEQKEKNSILWVKLNKIPIQDTKFK 26354
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ E V AEN +G ++ V + +PP I S + L W
Sbjct 26355 TTGLDEGLEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIVITRNS--VTLKW 26412
Query 245 TNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
P I Y ++ + W + + + FTV L Y FR+
Sbjct 26413 KKPVYDGGSKITGYIVEKKDLPDGRWMKASFTNVV--ETEFTVTGLVEDQRYEFRVIARN 26470
Query 304 EDGKGYWSDWSEEASGITYED---RPSKAPSFWYKIDPSHTQGYRTVQ---LVWKTLP-- 355
+S+ SE + IT D P+ + Y+ G V + K +P
Sbjct 26471 AADN--FSEPSESSGAITARDEIDAPNASLDPKYRDVIIVHAGETFVLEADIRGKPIPDI 26528
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT 415
+ +G L+ KS LQ T+ + D TL + N+ G +
Sbjct 26529 IWSKDGNELEETAARMEIKSTLQKTTLIVKDC---IRTDGGQYTLKLSNVGGTKTIPITV 26585
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
+ + + ++ W P + I + ++ + W Q
Sbjct 26586 KVLDRPGPPEGPLKVTGVTAEKC-YLAWNPPLQDGGASISHY-IIEKRETSRLSWTQVSN 26643
Query 476 TVHRT-YLRGNLAESKCYLITVTPVYADGPGS---PESIKAYLKQAPPSKGPTVRTKKVG 531
V Y L Y+ V V G G E + A P T +
Sbjct 26644 EVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEALESEPVIACNPYKRPGPPSTPEASAIT 26703
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDS-SHTEYTLSSLTSDTLYM 589
K+ VL W + PVD I Y + R G T N + + + ++ LT Y
Sbjct 26704 KDSMVLTWTR-PVDDGGAEIEGYILEKRDKEGIRWTKCNKKTLTDLRFRVTGLTEGHSYE 26762
Query 590 VRMAAYTDEGGKDGPEFTF 608
R+AA G + E +
Sbjct 26763 FRVAAENAAGVGEPSEPSV 26781
Score = 170 bits (429), Expect = 2e-41, Method: Composition-based stats.
Identities = 96/514 (19%), Positives = 157/514 (31%), Gaps = 53/514 (10%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWD-GGRETHLETN-FTLKSEWATHKFADCKAK 175
I + P +NL ++ W+ + + + ++ K
Sbjct 14871 INLQVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLVTD 14930
Query 176 RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS----DHINFDPVYKVKPNPPHNLSVI 231
R TV V V A N +G + Y V P PP N+++
Sbjct 14931 RADSCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDSPVEARSKYDV-PGPPLNVTIT 14989
Query 232 NSEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + LTW P I Y I+ R K + W S TV D+
Sbjct 14990 DVNRFG--VSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAED--LSATVTDVV 15045
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
EY FR+R G G S + +RPS + + Q +VQL
Sbjct 15046 EGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLN-----ASEQTQSSVQLT 15100
Query 351 WKTLPPFEANGKILDYEVTLTRWKSHLQ------NYTVNATKLTVNLTNDRYLATLTVRN 404
W+ P + IL Y + K+T ++YL ++ N
Sbjct 15101 WEP-PLKDGGSPILGYIIERREEGKDNWIRCNMKPVPELTYKVTGLQKGNKYLYRVSAEN 15159
Query 405 LVGKSDAAVLTIP-ACDFQATHPVMDLKA--------FPKDNMLWVEWTTPRESVKKYIL 455
G SD + + P D P MDL A P + V T +
Sbjct 15160 AAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPIKILVPSTGYPRPKATWTF 15219
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
VL + + + Y +T+ +K+
Sbjct 15220 GDQVLEEGDR--VKMKTISAYAELVISPSERTDKGIYTLTLEN----------PVKSISG 15267
Query 516 Q------APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAV 568
+ APPS ++ + K+ L W+ P D + Y + R + T V
Sbjct 15268 EINVNVIAPPSAPKELKFSDITKDSVHLTWEP-PDDDGGSPLTGYVVEKRDMSRKTWTKV 15326
Query 569 NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ E+T+ L Y+ ++ A G +
Sbjct 15327 MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGE 15360
Score = 167 bits (422), Expect = 1e-40, Method: Composition-based stats.
Identities = 105/606 (17%), Positives = 186/606 (31%), Gaps = 74/606 (12%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTI------INRTASSVTFTDIASLNI-QLTCNILTF 108
D + I W N I K T+ ++R+ + + + + T I
Sbjct 17210 DVTGLPMPKIEWSKNEKVIDKPTDTLNITKEEVSRSEAKTELSIPKAAREDKGTYTITAS 17269
Query 109 GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTL-KSEWA 165
+L + + P P+NL+ + + WD + T++ + K + +
Sbjct 17270 NRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYIIDKRDAS 17329
Query 166 THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV---TSDHINFDPVYKVKP 222
K + + + E V A N G SD + Y++ P
Sbjct 17330 RKKSEWEEVTNTAVERRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRL-P 17388
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTAS-- 279
PP V+ E + ++WT P I Y ++ R + + WS++
Sbjct 17389 GPPGKPKVL--ERTKGSMLVSWTPPLDNGGSPITGYWLEKREEGGTYWSRVSRAPITKVG 17446
Query 280 -TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA--PSFWYKI 336
F V L +Y FR + G G S+ S+ A P P
Sbjct 17447 LKGVEFNVPRLIEGVKYQFRAMAINAAGIGPPSEPSDPAVAGDPIYPPGPPSCPEV---- 17502
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH------LQNYTVNATKLTVN 390
+ ++ L WK P + I Y V + + + + A + V
Sbjct 17503 ---KDKTKSSISLAWKP-PAKDGGSPIKGYIVEMQEEGTTDWKPVNEPDKLLTACECVVP 17558
Query 391 LTND--RYLATLTVRNLVGKSDAAVLT--IPACDFQATHPV------MDLKAFPKDNMLW 440
+ +Y + N G+S+ + T IPA D Q V D + +
Sbjct 17559 NLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEVPEVFIDIGAQDCLVCKAGSQVK 17618
Query 441 V------------EWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+ W ++++K + + + R +
Sbjct 17619 IPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECTRAH---- 17674
Query 486 LAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
S Y IT + P ++ + + L W +P D
Sbjct 17675 ---SGKYSITAKNKAGQKTANCRVKVMD----APGPPKDLKVSDITRGSCRLSWK-MPDD 17726
Query 546 VQNGFIRNYTIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
I+ Y I +TI G T VN + T + + L S+ Y R+ A G
Sbjct 17727 DGGDRIKGYVIEKKTIDGKAWTKVNPNCGSTTFVVPDLISEQQYFFRVRAENRFGIGPPA 17786
Query 605 EFTFTT 610
E T
Sbjct 17787 ETIQRT 17792
Score = 164 bits (415), Expect = 9e-40, Method: Composition-based stats.
Identities = 96/606 (16%), Positives = 175/606 (29%), Gaps = 50/606 (8%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNIL-----TFGQ 110
I W + + +E+ + ++ TF ++N + + G+
Sbjct 21505 PVKGRPPPKITWSKPNVNL-RERIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGK 21563
Query 111 LEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLET--NFTLKSEWATHK 168
E + + + P P N++ WD N+ ++ A K
Sbjct 21564 KEYTIVVKVLDT---PGPPVNVTVKEVSKDSAYVTWDPPIIDGGSPIINYVVEKRDAERK 21620
Query 169 FADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL 228
+ TS V + V AEN G P P +L
Sbjct 21621 SWSTVTTECSKTSFRVSNLEEGK-SYFFRVFAENEYGIGDPGETRDAVKASETPGPVVDL 21679
Query 229 SVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
+ S + W P S I Y + + T++ W ++ S ++ +
Sbjct 21680 KALAI--TKSSCTIGWKKPRSDGGSRITGYVVDFLTEENK-WQRVM----KSLSLQYSTK 21732
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR-- 345
DLK EY FR+ E+G+G S+ A +R
Sbjct 21733 DLKEGKEYTFRVSAENENGEGTPSEIVVVAKDDVVAPDLDLKDLPDLCYLAKENSNFRLK 21792
Query 346 -------TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL-TNDRYL 397
+ WK + T + +++ VN T + + +D
Sbjct 21793 IPIKGKPAPSVSWKK--GEDPL---------ATDTRVSVESTAVNTTLVVYDCQKSDAGK 21841
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
T+T++N+ G L+I + ++W P++ I +
Sbjct 21842 YTITLKNVAGT-KEGTLSIKVVGKPGIPTGPIKFDEVTAEAMTLKWGPPKDDGGSEITNY 21900
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG---SPESIKAYL 514
+ + T+ L E Y V+ G G E I A
Sbjct 21901 VLEKRDSVNNKWVTCASAVQKTTFRVTRLHEGIEYTFRVSAENKYGVGEGLKSEPIVAKH 21960
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN--ETAVNVDS 572
P P V + L W P I Y I ++ + A
Sbjct 21961 PFDVPDAPPPPNIVDVRHDSVSLTWTD-PKKTGGSPITGYHIEFKERNSLLWKRANKTPI 22019
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLT 632
++ ++ LT Y R+ A G P + P A I+ P ++
Sbjct 22020 RMKDFKVTGLTEGLEYEFRVMAINLAGVGK-PSLP-SEPVVALDPIDPPGKPEVISVTRN 22077
Query 633 TLLGVL 638
++ +
Sbjct 22078 SVTLIW 22083
Score = 164 bits (415), Expect = 9e-40, Method: Composition-based stats.
Identities = 91/604 (15%), Positives = 181/604 (30%), Gaps = 39/604 (6%)
Query 41 HSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQ 100
S T V K W+T T+ + T+ T S+ +A+ N
Sbjct 15901 GSPITNYIVEKRDVRRKG--------WQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAI 15952
Query 101 LTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNF 158
+ G +V + P P L+ + + + +W+ + +
Sbjct 15953 GQSDYTEIG---DSVLAKDTFTT--PGPPYALTVVDVTKRHVDLKWEPPKNDGGRPIQRY 16007
Query 159 TLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-TSDHINFDPV 217
++ + K P + ++ V AEN G S+ +
Sbjct 16008 IIEKKEKLGTRWVKAGKTSGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSI 16067
Query 218 YKV--KPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPP 274
P+PP +L V ++ + + W P I+ Y+++ W ++
Sbjct 16068 EDPTSPPSPPLDLHVTDAGRK--HIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNS 16125
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
+ + + P EYV R+R + G S+ SE + +P+
Sbjct 16126 RPIKDLKFKVE-EGIVPDKEYVLRVRAVNAVGVSEPSEISENVVAKDPDCKPTIDLETHD 16184
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND 394
+ + + + ++ +P + EV + + ++ ++ ++ D
Sbjct 16185 IVVIEGEKL--NIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVHAD 16242
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI 454
+ T+T+ N +G S A + + + K + + W P I
Sbjct 16243 AGVYTITLENKLG-SATASINVKVIGLPGPCKDIKASDITKSSC-KLTWEPPEFDGGSPI 16300
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG----SPESI 510
L + + +A T G ++ +L + Y V V G G +
Sbjct 16301 LHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKIGGGEYIELKNPV 16360
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
A + PP V + W P+ I Y I I
Sbjct 16361 IAQDPKQPPDPPVDVEVHNPTAKAMTITWKP-PLYDGGSKIMGYII---EKITKGEDRWK 16416
Query 571 DSSHT-----EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPV 625
+ YT L Y R+ A G + T T + +++
Sbjct 16417 RCNEHLVPVLTYTAKGLEEGKEYQFRVRAENAAGIGEPSRATPPTKAVDPIDAPKVILRT 16476
Query 626 CLAF 629
L
Sbjct 16477 SLEV 16480
Score = 164 bits (415), Expect = 9e-40, Method: Composition-based stats.
Identities = 97/502 (19%), Positives = 166/502 (33%), Gaps = 42/502 (8%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCT 183
P P ++ + W+ E TN+ + + + TSCT
Sbjct 21178 PGPPASVKINKMYADRAMLSWEPPLEDGGSEITNYIIDKRETSRPNWAQVSATVPITSCT 21237
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDP-VYKVKPNPPH--NLSVINSEELSSIL 240
V+ + + AEN G D I +P + K +PP + VI S +
Sbjct 21238 VEKLIEGH-EYQFRICAENKYGVG--DPILTEPAIAKNPYDPPGRCDPPVI-SNITKDHM 21293
Query 241 KLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
++W P I Y ++ R A W+++ + + L+ TEY FR+
Sbjct 21294 TVSWKAPADDGGSPITGYLVEKRETQAVNWTKVNRKPVI--ERTLKATGLQEGTEYEFRV 21351
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
+ + G G SD S+ P P+F D + + +V L W P ++
Sbjct 21352 TAINKAGPGKPSDASKAVYAQDPLYPP-GPPAFPKVYDTTRS----SVSLSW-GKPAYDG 21405
Query 360 NGKILDYEVTLTRWKS-HL------QNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
I+ Y V + R S H + ++T + N Y + N +G SD +
Sbjct 21406 GSPIIGYLVEVKRADSDHWVRCNLPEKLQKTRFEVTGLMENTEYQFRVYAVNKIGYSDPS 21465
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVE-------WTTPRESVKKYILEWCVLSDKAP 465
+ C P L + + + I W +
Sbjct 21466 DVPDKHCPKDILIPPEGELDAELRKTLILRAGVTMRLYVPVKGRPPPKIT-WSKPNVNLR 21524
Query 466 CITDWQQEDGTVHRTYLRGNLAES--KCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
+ N+ + Y++T+ + G E P
Sbjct 21525 ERIGLDIKSTDFDTFLRCENVNKYDAGKYILTL----ENSCGKKEYTIVVKVLDTPGPPV 21580
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNVDSSHTEYTLSSL 582
V K+V K+ A + WD P+ I NY + R + V + S T + +S+L
Sbjct 21581 NVTVKEVSKDSAYVTWDP-PIIDGGSPIINYVVEKRDAERKSWSTVTTECSKTSFRVSNL 21639
Query 583 TSDTLYMVRMAAYTDEG-GKDG 603
Y R+ A + G G G
Sbjct 21640 EEGKSYFFRVFAENEYGIGDPG 21661
Score = 164 bits (414), Expect = 1e-39, Method: Composition-based stats.
Identities = 102/598 (17%), Positives = 180/598 (30%), Gaps = 51/598 (9%)
Query 72 FTIPKEQYTIINR--TASSVTFTDIASLNIQLTCNILTFGQLEQNVYGI--TIISGL--- 124
++I K + + N SSV T N+ + + F +N YG+ + S +
Sbjct 29481 YSIEKREASQTNWKMVCSSVARTTFKVSNL-VKDSEYQFRVRAENRYGVSEPLASNIIVA 29539
Query 125 --------PPEKPKNLSCIVNEGKKMRCEWD-GGRETHLE-TNFTLKSEWATHKFADCKA 174
PP KP + M WD + E T F ++ +
Sbjct 29540 KHQFRIPGPPGKPVIYN---VTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQRVN 29596
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKP-NPPHNLSVIN 232
+ ++ + V AEN+ G SD F V P +PP I+
Sbjct 29597 TSPISGREYRATGLIEGLDYQFRVYAENSAGLSSPSDPSKFTLA--VSPVDPPGTPDYID 29654
Query 233 SEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ L W P I+ Y+I+ R + + W + T + +TV L P
Sbjct 29655 VTRE--TITLKWNPPLRDGGSKIVAYSIEKR-QGSDRW--VRCNFTDVSECQYTVTGLSP 29709
Query 292 FTEYVFRIRCMKEDG-KGYWSDWSEEASGITYEDRPS---KAPSFWYKIDPSHTQGYRTV 347
Y FRI G S S P+ F + S
Sbjct 29710 GDRYEFRIIARNAVGTISPPSQSSGLIMTRDENVPPTVEFGPEYFDGLVIKSGDSLRIKA 29769
Query 348 QLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND-RYLATLTVRNLV 406
+ + +P ++ R + + + + + T D R + T+ +N+
Sbjct 29770 LVQGRPVPRVTWFKDGVE---IERRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNVS 29826
Query 407 GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
G + A V + + M + W P + + ++ +
Sbjct 29827 GSTKAEVTVKVQDTPGKVVGPIRFTNITGEKMT-LWWEAPLNDGCAPVTHY-IIEKRETS 29884
Query 467 ITDWQQEDGTVHR-TYLRGNLAESKCYLITVTPVYADGPGSP---ESIKAYLKQAPPSKG 522
W + +Y L Y ++ V G G P + + A ++ P
Sbjct 29885 RLAWALIEDNCEALSYTAIKLITGNEYQFRISAVNKFGVGRPLESDPVVAQIQYTIPDAP 29944
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNV--DSSHTEYTL 579
V N L W + P I++Y + R V S T + +
Sbjct 29945 GVPEPSNVTGNSITLTWTR-PESDGGSEIQHYILERREKKSTRWVKVISKRPISETRFKV 30003
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGV 637
+ L Y + A G GP + + + P + T+ V
Sbjct 30004 TGLVEGNEYEFHVMAENAAGI--GPASGISRLIKCREPVNPPSAPSVVKVTDTSKTTV 30059
Score = 164 bits (414), Expect = 1e-39, Method: Composition-based stats.
Identities = 94/572 (16%), Positives = 186/572 (33%), Gaps = 41/572 (7%)
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISG-------------LPPEKPKNLSCIVNEG 139
DI + + T + + + Y +T+ + P P ++
Sbjct 30192 DIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGKKSITFTVKVLDSPGPPGPITFKDVTR 30251
Query 140 KKMRCEWDGGRETHLET--NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
WD ++ ++ A+ + +++ V
Sbjct 30252 GSATLMWDAPLLDGGARIHHYVIEKREASRRSWQVVSEK-CTRQILKVSELTEGVPYYFR 30310
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILK 256
V AEN G + V +P PP L V+++ + S++ L W P I
Sbjct 30311 VSAENEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAV--LAWLKPDHDGGSRITS 30368
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y ++ R K + W E + + +FTV+ L TEY FR++ + G +
Sbjct 30369 YLLEMRQKGSDFW----VEAGHTKQLTFTVERLVENTEYEFRVKAKNDAGYSEPREAFSS 30424
Query 317 ASGITYEDRPSKAPS-FWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
+ P+ + ++ T+ + P + K+ + + T S
Sbjct 30425 VIIKEPQIEPTADLTGITNQLITCKAGSTFTIDVPISGRPAPKVTWKLEEMRLKETDRMS 30484
Query 376 HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK 435
+ ++ D LT+ N G + + +++ +
Sbjct 30485 IATTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFTITVVVIGRPGPVTGPIEVSSVSA 30544
Query 436 DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLI 494
++ + + WT P++ I + ++ + T WQ + +V RT ++ +L + K Y
Sbjct 30545 ESCV-LSWTEPKDDGGTEITNY-IVEKRESGTTAWQLINSSVKRTQIKVTHLTKYKEYCF 30602
Query 495 TVTPVYADGPGSP-ESIKAYLKQA--PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
V+ G P ES+ + PPS V N + W++ P I
Sbjct 30603 RVSSENRFGVSKPLESVPIVAEHPFVPPSAPTRPEVYYVSANAMSIRWEE-PYHDGGSKI 30661
Query 552 RNYTIFYRTIIGNETAVNVDSS-----HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
Y + T + V + Y ++ L Y R A G E
Sbjct 30662 VGY---WVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEA 30718
Query 607 TFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
+ P AQ ++ P +T+ +
Sbjct 30719 --SRPIMAQNPVDPPGRPEVTDVTRSTVSLIW 30748
Score = 163 bits (411), Expect = 2e-39, Method: Composition-based stats.
Identities = 88/495 (18%), Positives = 162/495 (33%), Gaps = 35/495 (7%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCT 183
P P N + C+W+ + N+TL+ + T +D T +C
Sbjct 16591 PGPPINFVFEDIRKDSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSDWIVITSTLRNCK 16650
Query 184 VDYSTVYF-VNIEVWVEAENALGKVT---SDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ + V AEN G S + + P+ P V + S +
Sbjct 16651 YSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLLAKDPF-EPPDAPDKPIVEDVTSNSML 16709
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+K W P IL Y ++ R +++ WS++ +S ++ V L YVFR+
Sbjct 16710 VK--WNEPKDNGSPILGYWLEKREVNSTHWSRVNKTLLSSLKT--KVDGLLEGLTYVFRV 16765
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
G G +S S+ + R +P + T T++L W+ P F
Sbjct 16766 CAENAAGPGKFSPPSDPKT-----ARDPISPPGPPVPRVADTSST-TIELEWEP-PAFNG 16818
Query 360 NGKILDY----EVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAAV 413
G+I+ Y ++ T S + + TV Y ++ N G+
Sbjct 16819 GGEIMGYFVDKQLVGTNEWSRCTEKMIKVRQFTVKEIREGADYKLRVSAVNAAGEGPPGE 16878
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTT---PRESVKKYI--LEWCVLSDKAPCIT 468
P ++L K + + T P E + + W + +
Sbjct 16879 TEPVTVAEPQEPPTVELDVSVKGGIQIMAGKTLRIPAEVTGRPVPTKVWTIEEGELDKER 16938
Query 469 DWQQEDGTVHRTYLRGNL-AESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
+ GT ++ L + Y+IT T GS + P ++
Sbjct 16939 VIIENVGTKSELIIKNALRKDHGRYVITATN----SCGSKFAAVRVEVFDVPGPVLDLKP 16994
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTL 587
+ +L W P D I + I + + +++ ++ ++ L
Sbjct 16995 VVTNRKMCLLNWSD-PADDGGSDITGFIIERKDAKMHTWRQPIETERSKCDITGLIEGQE 17053
Query 588 YMVRMAAYTDEGGKD 602
Y R+ A G
Sbjct 17054 YKFRVIAKNKFGCGP 17068
Score = 161 bits (407), Expect = 9e-39, Method: Composition-based stats.
Identities = 98/593 (17%), Positives = 168/593 (28%), Gaps = 32/593 (5%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNI-QLTCNILTFGQLEQN 114
A + W ++ + + + + + + + I +
Sbjct 22588 PIKGRPAPEVTWTKDNINLKHRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSG 22647
Query 115 VYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADC 172
+ ++ P NL + WD TN+ ++ AT K
Sbjct 22648 FVNVRVL--DTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYST 22705
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
+ V AEN G P PP +L++++
Sbjct 22706 VTTK-CHKCTYKVTGLTEGCEYFFRVMAENEYGVGEPTETTEPVRASEAPLPPDSLNIMD 22764
Query 233 SEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ + L W P I Y I+ + K + W+ I V++L
Sbjct 22765 I--TKNTVSLAWPKPRHDGGSKITGYVIEAQRKGSDQWTHIS----TVKGLECVVRNLTE 22818
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS---FWYKIDPSHTQGYRTVQ 348
EY F++ + G+ S E I E + K+ + V+
Sbjct 22819 GEEYTFQVMAVNSAGR---SAPRESRPVIVKEQTMLPELDLRGIYQKLVIARAGDNIKVE 22875
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK 408
+ P K D + T+ + T + + +D LT +N VG+
Sbjct 22876 IPVLGRPKPTVTWKKGDQILKQTQRVNVENTATSTILNINECVRSDSGPYPLTAKNTVGE 22935
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCIT 468
V+TI D + + W P I + V + T
Sbjct 22936 -VGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWEPPENDGGVPISNYVVEMRQTDSTT 22994
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS---PESIKAYLKQAPPSKGPTV 525
+ + TY L Y V G G S+ A P T
Sbjct 22995 WVELATTVIRTTYKATRLTTGVEYQFRVRAQNRYGVGPGITSASVVANYPFKVPGPPGTP 23054
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG----NETAVNVDSSHTEYTLSS 581
+ V K+ + W P+ I Y I + G + V + + T
Sbjct 23055 QVTAVTKDSMTISW-HEPLSDGGSPILGYHIERKERNGILWQTVSKALVPGNIFKST--G 23111
Query 582 LTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTL 634
LT Y R+ A G + + P FA I+ PV L T+
Sbjct 23112 LTDGIAYEFRVIAENMAGKSKPSKP--SEPMFALDPIDPPGKPVPLNITRHTV 23162
Score = 160 bits (405), Expect = 1e-38, Method: Composition-based stats.
Identities = 106/612 (17%), Positives = 194/612 (32%), Gaps = 70/612 (11%)
Query 78 QYTIINRTASSVTFTDIASLNIQL--------TCNILTFGQLEQNVYGI-------TIIS 122
Y ++ R S+ ++++++ + T F +N +GI ++
Sbjct 28393 NYIVLKRETSTAVWSEVSATVARTMIKVMKLTTGEEYQFRIKAENRFGISDHIDSVCVVV 28452
Query 123 GLP---PEKPKNLSCIVNEGKKMRCEWD-GGRETHLE-TNFTLKSEWATHKFADCKAKRD 177
LP P P + + W T + L+ + K
Sbjct 28453 KLPYTTPGPPSTPWVSNVTRESITVGWHEPVSNGGSAVTGYHLEMKDRNSILWQKANKMI 28512
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
T+ + + E V AENA G H + + PP N+ + + + S
Sbjct 28513 IRTTHFKVTTISAGLIYEFRVYAENAAGIGKPSHPSEPVLAIDACEPPRNVRITDISKNS 28572
Query 238 SILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
+ L+W P+ I Y ++ R W++ + + FTV L ++Y
Sbjct 28573 --VNLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVI--ETQFTVSGLTQNSQYE 28628
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ-------L 349
FR+ G S+ SE IT D P ++ + YR +
Sbjct 28629 FRVFARNAV--GSVSNPSEVVGPITCIDS-YGGPVIDLPLEYTEVVKYRAGTSVKLRAGI 28685
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND-----RYLATLTVRN 404
K P E Y+ +++ N+T L L D L +RN
Sbjct 28686 SGKPEPTIEW------YK-DDKELQTNALVCVENSTDLASILIKDANRLNSGSYELKLRN 28738
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
+G + A + ++ K + + + W P + I + ++ +
Sbjct 28739 AMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLL-WRPPADDGGAKITHY-IVEKRE 28796
Query 465 PCITDWQQEDGTVHR-TYLRGNLAESKCYLITVTPVYADGPGSP---ESI---KAYLKQA 517
W + + + Y+ V V G G P E + A++
Sbjct 28797 TSRVVWSMVAENLEECIVTTTKIIKGNEYVFRVRAVNKYGIGEPLESEPVVAKNAFVTPG 28856
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHT 575
PPS K+ KN + WD+ P I Y + R + T
Sbjct 28857 PPSIP---EVTKITKNSMTVVWDR-PTVDGGSEINGYFLERRDKKSLAWLKVLKETIRDT 28912
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK---FAQGEIEAIVVPVCLAFLLT 632
++ LT ++ Y R+ A G F+ P A I+ P + +
Sbjct 28913 RQKVTGLTENSDYQYRVCAVNAAGVGP-----FSEPSDFYKAADPIDPPGPPAKIRIADS 28967
Query 633 TLLGVLFCFNKR 644
T + ++K
Sbjct 28968 TKSSITLGWSKP 28979
Score = 160 bits (403), Expect = 2e-38, Method: Composition-based stats.
Identities = 85/563 (15%), Positives = 164/563 (29%), Gaps = 33/563 (6%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNV 115
+ I W I II+ T S + + +N + +
Sbjct 31258 SVSGRPSPVITWSKKG--IDLANRAIIDNTES-YSLLIVDKVNRYDAGKYTIEAENQSGK 31314
Query 116 YGITIISGLPPEKPK---NLSCIVNEGKKMRCEWD-GGRETHLE-TNFTLKSEWATHKFA 170
T++ + P ++S + W+ + N+ ++ A +
Sbjct 31315 KSATVLV-KVYDTPGPCPSVSVKEVSRDSVTITWEIPTIDGGAPVNNYIIEKREAAMRAF 31373
Query 171 DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
+ + T + + V EN G + + P P L V
Sbjct 31374 KTVTTKCSKTLYRISGLVEGTMYY-FRVLPENIYGIGEPCETSDAVLVSEVPLVPTKLEV 31432
Query 231 INSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
++ S + L W P + Y ++ W ++ T TV L
Sbjct 31433 VDV--TKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVT--LKPTVLEHTVISL 31488
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR-TVQ 348
+Y+FR+R E G + + P+ S + G +
Sbjct 31489 NEGEQYLFRVRAQNEKGVSEPREIVTPVTVQDLRVLPTIDLSTMPQKTIHVPAGRPIELV 31548
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK 408
+ PP A+ ++ + + + V + D TL ++N+ G
Sbjct 31549 IPITGRPPPTASWFFAGSKLRESERVTVETHTKVTKLTIRETTIRDTGEYTLELKNVTGT 31608
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES----VKKYILEWCVLSDKA 464
+ + I + + + + W P + Y++E +
Sbjct 31609 TSETIKVIILDKPGPPTGPIKIDEIDA-TSVTISWEPPELDGGAPLSGYVVE-----QRD 31662
Query 465 PCITDWQQEDGTVHR-TYLRGNLAESKCYLITVTPVYADGPGS---PESIKAYLKQAPPS 520
W +V R T+ L E Y+ V G GS E I+ + P
Sbjct 31663 AHRPGWLPVSESVTRPTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSISIPG 31722
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYT 578
T++ V ++ L W P D + Y + + + + V + T Y
Sbjct 31723 PPETLQIFDVSRDGMTLTWYP-PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYR 31781
Query 579 LSSLTSDTLYMVRMAAYTDEGGK 601
+ L Y R+ A G
Sbjct 31782 STGLIEGLEYEHRVTAINARGTG 31804
Score = 160 bits (403), Expect = 3e-38, Method: Composition-based stats.
Identities = 95/563 (17%), Positives = 168/563 (30%), Gaps = 42/563 (7%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNI-QLTCNILTFGQLEQN 114
+ W I + + +S+ ++ + + T + +
Sbjct 24754 PIKGRPTPEVKWGKVDGDIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSA 24813
Query 115 VYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLET--NFTLKSEWATHKFADC 172
+T+ P P NL + W+ N+ ++ AT K
Sbjct 24814 F--VTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 24871
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
S +D V AEN G P PP ++V +
Sbjct 24872 VVTNCHKNSWKIDQLQEGCSYY-FRVTAENEYGIGLPARTADPIKVAEVPQPPGKITVDD 24930
Query 233 SEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
S + L+WT P I++Y ++ + K+ WS E + +L
Sbjct 24931 VTRNS--VSLSWTKPEHDGGSKIIQYIVEMQAKNTDKWS----ECARVKSLDAVITNLTQ 24984
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
EY+FR+ + E G+ + P P+F V +
Sbjct 24985 GEEYLFRVIAVNEKGRSDPRSLAVPIIAKDLVIEPDVRPAFSSYSVQVGQDLKIEVPISG 25044
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN---------DRYLATLTV 402
+ P ++ T+ L+ T +++LT D +TV
Sbjct 25045 RPKP-----------SISWTKDGMPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITV 25093
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD 462
N+VG+ AA+ I + ++ + + W P + I + V
Sbjct 25094 SNVVGQKTAAIEIITLDKPDPPKGPVKFDEISAES-ITLSWNPPLYTGGCQITNYIVQKR 25152
Query 463 KAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPG---SPESIKAYLKQAP 518
T W TV RT L+ L Y + G E + A
Sbjct 25153 DT-TTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESEPVVAQYPYKE 25211
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDSSH-TE 576
P T + K V++W P++ + Y + + T VN H T+
Sbjct 25212 PGPPGTPFVTAISKESMVVQW-HEPINNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQ 25270
Query 577 YTLSSLTSDTLYMVRMAAYTDEG 599
+ +L Y R+ A G
Sbjct 25271 FKALNLEEGIEYEFRVYAENIVG 25293
Score = 160 bits (403), Expect = 3e-38, Method: Composition-based stats.
Identities = 100/600 (17%), Positives = 190/600 (32%), Gaps = 37/600 (6%)
Query 57 YFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVY 116
+ W N +P+E +SS+ + + + ++L + +
Sbjct 18337 VSGKPPPTVTWSMNERALPQEAAIETTAISSSMVIKNCQRSHQGVY-SLLAKNEGGERKK 18395
Query 117 GITIISGLPPEKPKNLSCIVNEGKKMRC--EW-DGGRETHLE-TNFTLKSEWATHKFADC 172
I + P P + + + C W + TN+ ++ A +
Sbjct 18396 TIIVDVLDVPG-PVGIPFLSDNLTNDSCKLTWFSPEDDGGSPITNYVIQKREADRRAWTP 18454
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT---SDHINFDPVYKVKPNPPHNLS 229
T + TV + + AEN++G + + P P +L
Sbjct 18455 VTYTVTRQNATVQGLIQGK-SYFFRIAAENSIGMGPFVETPNALVIRDPITVPERPEDLE 18513
Query 230 VINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
V E + + LTW P I+ Y ++ R + ++ ++ S + +TV+
Sbjct 18514 VK--EVTKNTVSLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRK--YTVKG 18569
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
LK Y +R+ + G+G S ++ + P+ F K+ +
Sbjct 18570 LKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLDLDFRDKLTV-RVGESFALT 18628
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN----DRYLATLTVRN 404
+ P KI ++ + + T L + T D + V N
Sbjct 18629 GRYSGKPKP----KIDWFKDEADVLEDDRTHIKTTPTTLALEKTKAKRSDSGKYCVVVEN 18684
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
G S + D + + + W P + I + + +
Sbjct 18685 STG-SRKGFCQVNVVDRPGPPVGPVIFDEVTKEYMVISWKPPLDDGGSEITNYIIEKKEL 18743
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP---ESIKAYLKQAPPSK 521
+ T L E K Y+ + G P +S+KA + P
Sbjct 18744 GKDIWMPVTSASAKTTCKVPKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDA 18803
Query 522 GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNVDSSH--TEYT 578
+V K+ A++ W+ + I NY + R + V + H T+Y
Sbjct 18804 PEQPVVTEVTKDSALVTWN--KPNDGGKPITNYILEKRETMSKRWVRVTKEPIHPYTKYR 18861
Query 579 LSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGV 637
+ L Y R++A + G G P P FA+ I P+ + TT V
Sbjct 18862 VPDLLEGCQYEFRVSAENEIGIGDPSPPSK---PVFARDPIAKPSPPINPEAIDTTCNSV 18918
Score = 158 bits (400), Expect = 5e-38, Method: Composition-based stats.
Identities = 99/544 (18%), Positives = 166/544 (31%), Gaps = 50/544 (9%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCT 183
P +NL + W+ + TNF ++ K A T
Sbjct 19791 PGPCQNLKVSNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRL-- 19848
Query 184 VDYSTVYFVNIEVWVEAENALGKVTS-----DHINFDPVYKVKPNPPHNLSVINSEELSS 238
V + + V AEN +G + + +P+ + P P NL + + +
Sbjct 19849 VKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDR--PGEPENLHIADKG--KT 19904
Query 239 ILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ L W P L Y+++ R K ++ W ++ + + + V Y F
Sbjct 19905 FVYLKWRRPDYDGGSPNLSYHVERRLKGSADWERV--HKGSIKETHYMVDKCVENQIYEF 19962
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL----VWKT 353
R++ E G+ SDW + ED + T++L K
Sbjct 19963 RVQTKNEGGE---SDWVRTEEVVVKEDLQKPVLDLKLSG-VLTVKAGDTIRLEAGVRGKP 20018
Query 354 LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAV 413
P ++T + + + LT +D +T N G S A
Sbjct 20019 FPEVAWTKDKDATDLTRSPRVKIDTSAESSKFSLTKAKRSDGGKYVITATNPAG-SFVAY 20077
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES----VKKYILEWCVLSDKAPCITD 469
T+ D + + D + W P + ++ YILE C
Sbjct 20078 ATVNVLDKPGPVRNLKITDVSSDRCT-IRWDPPEDDGGCEIQNYILEKC-----ESKRMV 20131
Query 470 WQQEDGTV-HRTYLRGNLAESKCYLITVTPVYADGPGSP---ESIKAYLKQAPPSKGPTV 525
W V + L E Y+ V G G P + + A K P +
Sbjct 20132 WSTYSANVLTPSATVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDRPGRPDPP 20191
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSS-----HTEYTLS 580
KV K E + W+ D I Y Y V + +
Sbjct 20192 EVTKVSKEEMTVVWNAPEYDGGKS-ITGY---YLEKKEKHAVRWVPVNKSAIPERRLKVQ 20247
Query 581 SLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFC 640
+L Y R+ A + G + P + P A+ IE P + TT +
Sbjct 20248 NLLPGHEYQFRVKAENEVGIGE-PSLP-SRPVVAKDPIEPPGPPTNFKVVDTTKSSITLA 20305
Query 641 FNKR 644
+ K
Sbjct 20306 WGKP 20309
Score = 158 bits (399), Expect = 8e-38, Method: Composition-based stats.
Identities = 144/794 (18%), Positives = 248/794 (31%), Gaps = 100/794 (13%)
Query 66 VWKTNHFTIPKEQYTIIN-RTASSVTFTDI---ASLNIQLTCNILTFGQLEQNVYGITII 121
VW + KE+ I N T S + + +T + + +
Sbjct 16926 VWTIEEGELDKERVIIENVGTKSELIIKNALRKDHGRYVITATNSCGSKFAA----VRVE 16981
Query 122 SGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTP 179
P +L +V K W + T F ++ + A + +
Sbjct 16982 VFDVPGPVLDLKPVVTNRKMCLLNWSDPADDGGSDITGFIIERKDAKMHTWRQPIETERS 17041
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP-NPPHNL-SVINSEELS 237
C + + V A+N G + P+ V P PP + + +E
Sbjct 17042 K-CDITGLIEG-QEYKFRVIAKNKFGCGP--PVEIGPILAVDPLGPPTSPERLTYTERTK 17097
Query 238 SILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
S + L W P S I Y I+ R D + ++ +SF V++L Y
Sbjct 17098 STITLDWKEPRSDGGSPIQGYIIEKRRHDKPDFERVNKRLC--PTTSFLVENLDEHQMYE 17155
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ----LVWK 352
FR++ + + G+ S E P+ + D + V +
Sbjct 17156 FRVKAVNDVGESEPSLPLNVV-IQDDEVPPTIKLRLAVRGDTIKVKAGEPVNIPADVTGL 17214
Query 353 TLPPFEA--NGKILDYEVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGK 408
+P E N K++D + + T+L++ D+ T+T N +G
Sbjct 17215 PMPKIEWSKNEKVIDKPTDTLNITKEEVSRSEAKTELSIPKAAREDKGTYTITASNRLG- 17273
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA-PCI 467
S + + D + + + ++ ++ W P ++ I + + A
Sbjct 17274 SVFRNVHVEVYDRPSPPRNLAVTDIKAESC-YLTWDAPLDNGGSEITHYIIDKRDASRKK 17332
Query 468 TDWQQEDGT-VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP---PSKGP 523
++W++ T V R Y L + Y V V G + Q P P
Sbjct 17333 SEWEEVTNTAVERRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPG 17392
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS-- 581
+ + K ++ W P+D I Y + R G + + T+ L
Sbjct 17393 KPKVLERTKGSMLVSWTP-PLDNGGSPITGYWLEKREEGGTYWSRVSRAPITKVGLKGVE 17451
Query 582 -----LTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLG 636
L Y R A G GP + P A I P C
Sbjct 17452 FNVPRLIEGVKYQFRAMAINAAGI--GPPSEPSDPAVAGDPIYPPGPPSC---------- 17499
Query 637 VLFCFNKRDLIKKHIWPNVPDPSKSHIA-QWSPHTPPRHNFNSKDQMYSDGNFTDVSVVE 695
P V D +KS I+ W P P + S + Y V + E
Sbjct 17500 ----------------PEVKDKTKSSISLAWKP---PAKDGGSPIKGY------IVEMQE 17534
Query 696 IEANDKKPFPEDLKSL--------DLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDEN 747
D KP E K L +L + K + G S S + I ++D
Sbjct 17535 EGTTDWKPVNEPDKLLTACECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQ 17594
Query 748 ESSQNTSST-VQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEER----------PEDL 796
E + Q V +G + ++P+V + + D + + PED
Sbjct 17595 EVPEVFIDIGAQDCLVCKAGSQVKIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDA 17654
Query 797 QLVDHVDGGDGILP 810
QL + I+P
Sbjct 17655 QLETAENSSVIIIP 17668
Score = 158 bits (398), Expect = 1e-37, Method: Composition-based stats.
Identities = 95/591 (16%), Positives = 182/591 (31%), Gaps = 64/591 (11%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
+V+ S+FT + + + W + Y + + +T +
Sbjct 27986 IVKAGSSFTMT-------VPFRGRPIPNVSWSKPDTDLRTRAYIDSTDSRTLLTIENANR 28038
Query 97 LNI-QLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD-GGRETHL 154
+ + T I + + ++ P P N++ + WD +
Sbjct 28039 NDSGKYTLTIQNVLSAASMTFVVKVL--DSPGPPANITVREVTKETAMLSWDVPENDGGA 28096
Query 155 ET-NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN 213
N+ ++ A+ K + V EN G
Sbjct 28097 PVKNYHIEKREASKKAWVSVTNN-CNRLSYKVTNLQEGAIYYFRVSGENEFGVGVPAETK 28155
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQI 272
KP+PP L V + + L+W P I+ Y ++ K TW
Sbjct 28156 EGVKITEKPSPPEKLGVTSV--SKDSVSLSWLKPEHDGGSRIIHYVVEALEKGQKTW--- 28210
Query 273 PPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF 332
+ + V L+ EY FR+ + G SD E + +D+ + P
Sbjct 28211 -VKCAVVKTTHHVVSGLRESHEYFFRVFAENQAGL---SDPRELLLPVLIKDQ-LEPPEI 28265
Query 333 WYKIDPSHTQGYRT-------VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT 385
K PSHT R + + K LP VTL+R L+ T
Sbjct 28266 DMKNFPSHTVYVRAGSNLKVDIPISGKPLPK-----------VTLSRDGVPLKATMRFNT 28314
Query 386 KLTVN---------LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
++T +T D +T N G + + I + + ++
Sbjct 28315 EITAENLTINLKESVTTDAGRYEITAANSSGTTKTFINIIVLDRPGPPTGPVAISDITEE 28374
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG-NLAESKCYLIT 495
+ + ++W P+ ++ + VL + W + TV RT ++ L + Y
Sbjct 28375 S-VTLKWEPPKYDGGSHVTNYIVLKRETSTAV-WSEVSATVARTMIKVMKLTTGEEYQFR 28432
Query 496 VTPVYADGPG---SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
+ G + L P T V + + W PV +
Sbjct 28433 IKAENRFGISDHIDSVCVVVKLPYTTPGPPSTPWVSNVTRESITVGW-HEPVSNGGSAVT 28491
Query 553 NYTIFYRTII----GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
Y + + + + ++H + T ++++ +Y R+ A G
Sbjct 28492 GYHLEMKDRNSILWQKANKMIIRTTHFKVT--TISAGLIYEFRVYAENAAG 28540
Score = 157 bits (397), Expect = 1e-37, Method: Composition-based stats.
Identities = 87/493 (18%), Positives = 165/493 (33%), Gaps = 30/493 (6%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCT 183
PP+ P M +W+ ++ + L+ K + T
Sbjct 16691 PPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKTLLSSLKT 16750
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
+ + V AENA G + + +PP ++ S+ ++L
Sbjct 16751 KVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTARDPISPPGPPVPRVADTSSTTIELE 16810
Query 244 WTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
W P+ I+ Y + + + WS+ + FTV++++ +Y R+ +
Sbjct 16811 WEPPAFNGGGEIMGYFVDKQLVGTNEWSRCTEKMIKV--RQFTVKEIREGADYKLRVSAV 16868
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ----LVWKTLPPFE 358
G+G + +E + ++ P+ K G +T++ + + +P
Sbjct 16869 NAAGEGPPGE-TEPVTVAEPQEPPTVELDVSVKGGIQIMAG-KTLRIPAEVTGRPVPTKV 16926
Query 359 A---NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT 415
G++ V + + + NA L D +T N G S A +
Sbjct 16927 WTIEEGELDKERVIIENVGTKSELIIKNA------LRKDHGRYVITATNSCG-SKFAAVR 16979
Query 416 IPACDFQATHPVMDLKAFPKDNML-WVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED 474
+ D PV+DLK + + + W+ P + I ++ K + W+Q
Sbjct 16980 VEVFDVPG--PVLDLKPVVTNRKMCLLNWSDPADDGGSDITG-FIIERKDAKMHTWRQPI 17036
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE---SIKAYLKQAPPSKGPTVRTKKVG 531
T L E + Y V G G P I A PP+ + +
Sbjct 17037 ETERSKCDITGLIEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERT 17096
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS--SHTEYTLSSLTSDTLYM 589
K+ L+W + P I+ Y I R + T + + +L +Y
Sbjct 17097 KSTITLDWKE-PRSDGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYE 17155
Query 590 VRMAAYTDEGGKD 602
R+ A D G +
Sbjct 17156 FRVKAVNDVGESE 17168
Score = 156 bits (394), Expect = 3e-37, Method: Composition-based stats.
Identities = 81/508 (16%), Positives = 148/508 (29%), Gaps = 41/508 (8%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETN--FTLKSEWATHKFADCKAKRDTPTSCT 183
P PK+L R W + + + ++ + K K + ++
Sbjct 17701 PGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKKTIDGKAW-TKVNPNCGSTTF 17759
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYK-VKPNPPHNLSVINSEELSSILKL 242
V + V AEN G + P + + + + L
Sbjct 17760 VVPDLISEQQYFFRVRAENRFGIGPPAETIQRTTARDPIYPPDPPIKLKIGLITKNTVHL 17819
Query 243 TWTNP-SIKSVIILKYNIQYRTKD-----ASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
+W P + + Y ++ D W Q D FTV+DL EY
Sbjct 17820 SWKPPKNDGGSPVTHYIVECLAWDPTGKKKEAWRQCNRRDVE--ELEFTVEDLIEGGEYE 17877
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID-------PSHTQGYRTVQL 349
FR++ + E G S P+ + +++ + +G L
Sbjct 17878 FRVKAVNEAGVSKPSATVGPVIVKDQTCPPAIELKEFMEVEEGTDVNIVAKIKGVPFPTL 17937
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV---NLTNDRYLATLTVRNLV 406
W PP + + K V +H+ V+ T V + +D L ++T N +
Sbjct 17938 TWFKAPPKKPDSKEP---VVY---DTHVNKQVVDDTCTLVIPQSRRSDTGLYSITAVNNL 17991
Query 407 GK-SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAP 465
G S L + P+ + + + W P++ I + + +A
Sbjct 17992 GTASKEMRLNVLGRPGPPVGPIKFESI--SADQMTLSWLPPKDDGGSKITNYVIEKREAN 18049
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP---ESIKAYLKQAPPSKG 522
T + Y L E Y+ + G G P E A + P
Sbjct 18050 RKTWVRVSSEPKECMYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAP 18109
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT------E 576
V +N + W++ P + Y + +
Sbjct 18110 DKPTVSSVTRNSMTVNWEE-PEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVS 18168
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
Y ++ L + Y R+ A G
Sbjct 18169 YKVTGLIEGSDYQFRVYAINAAGVGPAS 18196
Score = 154 bits (389), Expect = 1e-36, Method: Composition-based stats.
Identities = 97/612 (16%), Positives = 172/612 (28%), Gaps = 55/612 (9%)
Query 69 TNHFTIPKEQYTIINR--TASSVTFTDIASLNIQLTCNILTFGQLEQNVYGI-------- 118
+ + + + + SVT + N F N +GI
Sbjct 31653 LSGYVVEQRDAHRPGWLPVSESVTRPTFKFTRLT-EGNEYVFRVAATNRFGIGSYLQSEV 31711
Query 119 --TIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKA 174
S P P+ L M W + T + ++ +
Sbjct 31712 IECRSSISIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVN 31771
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGK---VTSDHINFDPVYKVKPNPPHNLSVI 231
K + + + E V A NA G P P N V
Sbjct 31772 KVPVTMTRYRSTGLIEGLEYEHRVTAINARGTGKPSRPSKPTVAMDPIAPPGKPQNPRVT 31831
Query 232 NSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
++ S + L W+ P + + Y I+ + D W++ T + +T+ L
Sbjct 31832 DTTRTS--VSLAWSVPEDEGGSKVTGYLIEMQKVDQREWTKCNT--TPTKIREYTLTHLP 31887
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
EY FR+ G G ++ + P Y+ QG ++L
Sbjct 31888 QGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGVFVRQGG-VIRLT 31946
Query 351 WKTLPPFEANGKILDYEVTLTRWKSHLQNYT--------VNATKLTVNL--TNDRYLATL 400
I + +W Q+ + T+L + ND L
Sbjct 31947 ----------IPIKGKPFPVCKWTKEGQDISKRAMIATSETHTELVIKEADRNDSGTYDL 31996
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
+ N GK + ++ + + V W P + IL + +
Sbjct 31997 VLENKCGKKTVYIKVKVIGSPNTPEGPLEYDDIQARS-VRVSWRPPADDGGADILGYILE 32055
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-----ESIKAYLK 515
+ P + + + + L E+ Y V+ G P I
Sbjct 32056 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVIPKTPL 32115
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSS 573
P V K+ L W + P D + Y I + ++ +
Sbjct 32116 NPPEPPSNPPEVLDVTKSSVSLSWSR-PKDDGGSRVTGYYIERKETSTDKWVRHNKTQIT 32174
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTT 633
T YT++ L D Y R+ A D G + + P + + P L L +
Sbjct 32175 TTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPA--SEPVVCKDPFDKPSQPGELEILSIS 32232
Query 634 LLGVLFCFNKRD 645
V + K +
Sbjct 32233 KDSVTLQWEKPE 32244
Score = 153 bits (386), Expect = 2e-36, Method: Composition-based stats.
Identities = 105/580 (18%), Positives = 175/580 (30%), Gaps = 71/580 (12%)
Query 59 HVNANYIVWKTNHF--TIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVY 116
A + W+ + K Q +++ A V + + + ++ +
Sbjct 20421 GRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV 20480
Query 117 GITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADC-- 172
+ ++ P +L W T++ ++ A K
Sbjct 20481 NVKVL--DTPGPVADLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREAERKTWSTVT 20538
Query 173 -KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK---PNPPHNL 228
+ K+ + + YF V A N G I + P+PP L
Sbjct 20539 PEVKKTSFNVTNLVPGNEYF----FRVTAVNEYGPGVPTDIPKPVLASDPLSEPDPPRKL 20594
Query 229 SVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
V +E + L W P I Y I YR +D E + S V
Sbjct 20595 EV--TEMTKNSATLAWLPPLRDGGAKIDGYIISYREEDQPA--DRWTEYSVVKDLSLIVT 20650
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV 347
LK +Y FR+ G EA G+ YE + P + + + +
Sbjct 20651 GLKEGKKYKFRVAARNAVGVSMP----REAEGV-YEAKEQLLPPKILMPEQITIKAGKKL 20705
Query 348 QLVWKTLPPFEANGKILDYEVTLTRWK---------SHLQNYTVNATKLTVN---LTNDR 395
++ GK + +WK SHL + + + + + D
Sbjct 20706 RV------EAHVYGKPN----PICKWKKGDDEVVTSSHLAIHKADGSSVLIIKDVTRKDS 20755
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES----VK 451
+LT N G + P D+ D + W P E +
Sbjct 20756 GYYSLTAENSSGSDTQKIKVTVMDAPGPPQPPFDISEIDADAC-SLSWHIPLEDGGSNIT 20814
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVYADGPGSP--- 507
YI+E C +S DW +V +T G L + Y+ V G P
Sbjct 20815 NYIVEKCDVSRG-----DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTS 20869
Query 508 ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA 567
+ A PS+ R KV K+ + WD+ P I Y I + +
Sbjct 20870 PKMLAKFPFDVPSEPKNARVTKVNKDCIFVAWDR-PDSDGGSPITGYLIERKE---RNSL 20925
Query 568 VNVDSSH-----TEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ V ++ TEY + L Y R+ A G
Sbjct 20926 LWVKANDTIVRSTEYPCAGLVEGLEYSFRIYALNKAGSSP 20965
Score = 153 bits (386), Expect = 3e-36, Method: Composition-based stats.
Identities = 109/625 (17%), Positives = 196/625 (31%), Gaps = 68/625 (11%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTAS-SVTFTDIASLNIQLTCNILTFGQLEQN 114
I W + +P +Q T IN T S +T I + G N
Sbjct 25041 PISGRPKPSISWTKDG--MPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY---GITVSN 25095
Query 115 VYG--------ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEW 164
V G IT+ PP+ P + + + W+ T TN+ ++
Sbjct 25096 VVGQKTAAIEIITLDKPDPPKGP--VKFDEISAESITLSWNPPLYTGGCQITNYIVQKRD 25153
Query 165 ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV---TSDHINFDPVYKVK 221
T D + T+ V + + AEN G+ S+ + YK +
Sbjct 25154 TTTTVWDVVSATVARTTLKVTKLKTG-TEYQFRIFAENRYGQSFALESEPVVAQYPYK-E 25211
Query 222 PNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P PP V + S +++ W P + ++ Y+++ + +++ W+++ T
Sbjct 25212 PGPPGTPFVTAISKESMVVQ--WHEPINNGGSPVIGYHLERKERNSILWTKVN--KTIIH 25267
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
+ F +L+ EY FR+ G G S SE D P + K +
Sbjct 25268 DTQFKALNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEAIIVKRN--- 25324
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLT-----RWKSHLQNYTVNATKLTVNLTND- 394
+ L W T P ++ I Y V RW + LT D
Sbjct 25325 -----EITLQW-TKPVYDGGSMITGYIVEKRDLPEGRWMKASFTNVIETQFTVSGLTEDQ 25378
Query 395 RYLATLTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW-----------V 441
RY + +N G + + P + + +D ++ V
Sbjct 25379 RYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADV 25438
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
+++ + + A C + + D + Y++ + V
Sbjct 25439 HGKPLP--TIEWLRGDKEIEESARC--EIKNTDFKALLIVKDAIRIDGGQYILRASNVAG 25494
Query 502 DGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI 561
P ++K + PP V+ V + L W P+ I +Y + R
Sbjct 25495 -SKSFPVNVKVLDRPGPPEGP--VQVTGVTAEKCTLAWSP-PLQDGGSDISHYVVEKRET 25550
Query 562 IG-NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
T V + ++ L Y+ R+ A G + E P +
Sbjct 25551 SRLAWTVVASEVVTNSLKVTKLLEGNKYIFRIMAVNKYGVGEPLESA---PVLMKNPFVL 25607
Query 621 IVVPVCLAFLLTTLLGVLFCFNKRD 645
P L + C+N+ D
Sbjct 25608 PGPPKSLEVTNIAKDSMTVCWNRPD 25632
Score = 152 bits (384), Expect = 5e-36, Method: Composition-based stats.
Identities = 101/613 (16%), Positives = 194/613 (32%), Gaps = 55/613 (9%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT-------DIASLNIQLTCNILTF 108
+ + W + + + T ++ T D+ ++LT +
Sbjct 23959 PFIGRPPPAVTWHKDDIPLKQTTRVNAESTENNSLLTIKEACREDVGHYTVKLTNSA--- 24015
Query 109 GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH---LETNFTLKSEWA 165
G+ + + I + PP P + + + + W+ + + K + +
Sbjct 24016 GEATETLNVIVLDKPGPPTGPVKMDEVTAD--SVTLSWEPPKYDGGSSINNYIVEKRDTS 24073
Query 166 TH--KFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT---SDHINFDPVYKV 220
T + R T +C + + + AEN GK T S+ + +KV
Sbjct 24074 TTAWQIVSATVARTTIKACRLKTG----CEYQFRIAAENRYGKSTYLNSEPVVAQYPFKV 24129
Query 221 KPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
P PP V + +++ W P S ++ Y+++ + +++ W + T
Sbjct 24130 -PGPPGTPFVTLA--SKDSMEVQWHEPVSDGGSKVIGYHLERKERNSILW--VKLNKTPI 24184
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
++ F L+ EY FR+ G G S SE + D P + + +
Sbjct 24185 PQTKFKTTGLEEGIEYEFRVSAENIVGIGKPSKPSECYAAHDPCDPPGRPEAIIVTRN-- 24242
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEV-----TLTRW-KSHLQNYTVNATKLTVNLTN 393
+V L WK P ++ KI Y V RW K+ N ++T L +
Sbjct 24243 ------SVTLQWKK-PTYDGGSKITGYIVEKKELPDGRWMKASFTNIIDTQFEVTGLLED 24295
Query 394 DRYLATLTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK 451
RY + RN G + + P + + +D ++ + +
Sbjct 24296 HRYEFRVIARNAAGVFSEPSESTGAITARDEVEPPRISMDPKYRDTVVVQAGESFKIDAD 24355
Query 452 KY-----ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
Y +W + + + + + + G S
Sbjct 24356 IYGKPIPTTQWVKGDQELSSTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGEKS 24415
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NE 565
L + P +GP V V + L W P+ I NY + R
Sbjct 24416 VTINVKVLDRPGPPEGP-VAISGVTAEKCTLAWKP-PLQDGGSDITNYIVERRETSRLVW 24473
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPV 625
T V+ + + L Y+ R+ A G + E K +A P
Sbjct 24474 TLVDANVQTLSCKVLKLLEGNEYIFRIMAVNKYGVGEPLESESLIAKNPFVVPDAPKAPE 24533
Query 626 CLAFLLTTLLGVL 638
A +++ V
Sbjct 24534 VTAVTKDSMIVVW 24546
Score = 151 bits (382), Expect = 9e-36, Method: Composition-based stats.
Identities = 133/766 (17%), Positives = 231/766 (30%), Gaps = 82/766 (11%)
Query 30 YISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRT--AS 87
I PV V E C+ + + + ++ + K + S
Sbjct 30526 VIGRPGPVT---GPIEVSSVSAESCVLSWTEPKDDGGTEITNYIVEKRESGTTAWQLINS 30582
Query 88 SVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISG----------LPPEKPKNLSCIVN 137
SV T I ++ F +N +G++ +PP P
Sbjct 30583 SVKRTQIKVTHLTKY-KEYCFRVSSENRFGVSKPLESVPIVAEHPFVPPSAPTRPEVYYV 30641
Query 138 EGKKMRCEWDGGRETHLETNFTLKSEWATHKFADC-----KAKRDTPTSCTVDYSTVYFV 192
M W+ E + + + W K + + K V +
Sbjct 30642 SANAMSIRWE---EPYHDGGSKIVGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGL 30698
Query 193 NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKS 251
+ A NA G + + + + +PP V + S + L W+ P
Sbjct 30699 EYQFRTYALNAAGVSKASEASRPIMAQNPVDPPGRPEVTDVTR--STVSLIWSAPVYDGG 30756
Query 252 VIILKYNIQYRTKDASTWSQ-IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG-KGY 309
++ Y I+ + + + T + + FTV L Y FR+ G
Sbjct 30757 SKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISK 30816
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
S+ + + P + D + + L A G + ++
Sbjct 30817 GSESTGPVTCRDEYAPPKAELDARLQGDLVTIRAGSDLVL-------DAAVGGKPEPKII 30869
Query 370 LTRWKSHL--------QNYTVNATKLTVNL-TNDRYLATLTVRNLVGKSDAAVLTIPACD 420
T+ L Q AT + +D TLTV+N G +V+ + D
Sbjct 30870 WTKGDKELDLCEKISLQYTGKRATAVIKYCDRSDSGKYTLTVKNASGTKSVSVM-VKVLD 30928
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV-HR 479
+ + ++ + W+ P+E I + ++ + +W +G
Sbjct 30929 SPGPCGKLTVSRVTEEKCT-LAWSLPQEDGGAEITHY-IVERRETSRLNWVIVEGECLTA 30986
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSP---ESIKAYLKQAPPSKGPTVRTKKVGKNEAV 536
+Y+ L ++ Y V V G G P E I A PS+ GK +
Sbjct 30987 SYVVTRLIKNNEYTFRVRAVNKYGLGVPVESEPIVARNSFTIPSQPGIPEEVGAGKEHII 31046
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDS--SHTEYTLSSLTSDTLYMVRMA 593
++W + D N I NY + R T VN D T ++SL Y R+
Sbjct 31047 IQWTKPESDGGN-EISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVT 31105
Query 594 AYTDEGGKDGPE----FTFTTPKFAQGEIEA----------IVVPVCLAFLLTTLLGVLF 639
A G + E + P + G A I + + +
Sbjct 31106 AVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKRSISLAWTKPMYDGGTDIIGY 31165
Query 640 CFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSV-----V 694
++ W V + + I P + N +S
Sbjct 31166 VLEMQEKDTD-QWCRV--HTNATIRNNEFTVPDLKMGQKYSFRVAAVNAKGMSDYSETTA 31222
Query 695 EIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPS 740
EIE ++ P DL+ D KK I G S + S RPS
Sbjct 31223 EIEPVERLEIP-DLELADDLKKTVIVRAGASLRLM---VSVSGRPS 31264
Score = 150 bits (378), Expect = 2e-35, Method: Composition-based stats.
Identities = 103/559 (18%), Positives = 183/559 (33%), Gaps = 68/559 (12%)
Query 84 RTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGI------TIISGLP--PEKPKN-LSC 134
T SV T + + + C G+ + + T+ + P P +
Sbjct 21815 DTRVSVESTAVNTTLVVYDCQKSDAGKYTITLKNVAGTKEGTLSIKVVGKPGIPTGPIKF 21874
Query 135 IVNEGKKMRCEWDGGRETHLE--TNFTL-KSEWATHKFADCKAKRDTPTSCTVDYSTVYF 191
+ M +W ++ TN+ L K + +K+ C +
Sbjct 21875 DEVTAEAMTLKWGPPKDDGGSEITNYVLEKRDSVNNKWVTCA--SAVQKTTFRVTRLHEG 21932
Query 192 VNIEVWVEAENALGK---VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
+ V AEN G + S+ I + V PP + + LTWT+P
Sbjct 21933 IEYTFRVSAENKYGVGEGLKSEPIVAKHPFDVPDAPPPP---NIVDVRHDSVSLTWTDPK 21989
Query 249 IKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
I Y+I+++ +++ W + T F V L EY FR+ + G
Sbjct 21990 KTGGSPITGYHIEFKERNSLLWKR--ANKTPIRMKDFKVTGLTEGLEYEFRVMAINLAGV 22047
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
G S SE + D P K + +V L+W T P ++ K+ Y
Sbjct 22048 GKPSLPSEPVVALDPIDPPGKPEVISVTRN--------SVTLIW-TEPKYDGGHKLTGYI 22098
Query 368 VTLTRWKSHLQ------NYTVNATKLTVNLTNDRYLATLTVRNLVGK----SDAAVLTIP 417
V S N A +T + +Y + +N G S++ I
Sbjct 22099 VEKRDLPSKSWMKANHVNVPDCAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTGTIIC 22158
Query 418 ACDFQATHPVMD------LKAFPKDNM----LWVEWTTPRESVKKYILEWCVLSDKAPCI 467
+++A V+D L D++ + + +S + K
Sbjct 22159 KDEYEAPTIVLDPTIKDGLTVKAGDSIVLSAISILGKPLPKSS-------WSRAGKDIRP 22211
Query 468 TDWQQEDGTVHRTYLR---GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
+D Q T + L ++ Y IT T + E +K + P
Sbjct 22212 SDIAQITSTPTSSMLTVKYATRKDAGEYTITATNPFGTKE---EHVKVSVL-DVPGPPGP 22267
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDSSHTEYTLSSLT 583
+ V +A L W P++ I+ Y + R T V+ D + ++ L
Sbjct 22268 IEISNVSAEKATLTWTP-PLEDGGSPIKAYVLEKRETSRLLWTVVSEDIQACRHVVTKLI 22326
Query 584 SDTLYMVRMAAYTDEGGKD 602
Y+ R++A G +
Sbjct 22327 QGNEYLFRVSAVNHYGKGE 22345
Score = 150 bits (377), Expect = 3e-35, Method: Composition-based stats.
Identities = 112/633 (18%), Positives = 189/633 (30%), Gaps = 86/633 (14%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKE-QYTIINRTASSVTF 91
E VV+ + +++ V W T+ I + YT+ + SSV
Sbjct 19306 IEGLVVKAGTTVRFPAIIR-------GVPVPTAKWTTDGTEIKTDDHYTVETDSFSSVLT 19358
Query 92 ------TDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCE 145
D + ++ N + ++ + PP P N+ + + M
Sbjct 19359 IKNCLRKDTGEYQLTVS-NAAGTKTVAVHL--TVLDVPGPPTGPINI--LDVTPEYMTIS 19413
Query 146 WDGGRETHLET--NF------TLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
W ++ N+ T K W K K P
Sbjct 19414 WQPPKDDGGSPVINYIVEKQDTRKGTWGVVSAGSSKLKLKVPH-------LQKGCEYVFR 19466
Query 198 VEAENALGKVTS-DHINFDPVYKV-KPNPPHNLSVINSEELSSILKLTWTNP-SIKSVII 254
V+AEN +G D I +K P+PP V + E ++ ++WT P S I
Sbjct 19467 VKAENKMGVGPPLDSIPTVAKHKFSPPSPPGKPVVTDITENAA--TVSWTLPKSDGGSPI 19524
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
Y ++ R + T F V L Y FR+ G S S
Sbjct 19525 TGYYVERREITGKW---VRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSNPSPSS 19581
Query 315 EEASGITYEDRPSKAPSFWYKIDPS-HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
+ P I+P + + LVW T P + IL Y V +
Sbjct 19582 DPIKACRPIKPPGPP------INPKLKDKSKESADLVW-TKPLSDGGSPILGYVVEYQKP 19634
Query 374 KSHLQN-------YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
+ + A ++ + + Y + N+VG+ + L HP
Sbjct 19635 GTAQWDRINKDELIRQCAFRVPGLIEGNEYRFRIRAANIVGEGEPRELAESVIAKDILHP 19694
Query 427 VMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED------------ 474
+++ V V + I + + W +E
Sbjct 19695 PEVELDVTCRDVITVR-------VGQTIRILARVKGRPEPDITWSKEGKVLVKDKRVDLI 19747
Query 475 ---GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
V A+ Y+I+ GS I L + P ++ V
Sbjct 19748 HDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSA--IVNVLDR--PGPCQNLKVSNVT 19803
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
K + W+ P+D I N+ + YR ++ ++L ++ Y R
Sbjct 19804 KENCTISWEN-PLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLVKANLLANNEYYFR 19862
Query 592 MAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVP 624
+ A G GP TP A I+ P
Sbjct 19863 VCAENKVGV--GPTIETKTPILAINPIDRPGEP 19893
Score = 149 bits (376), Expect = 5e-35, Method: Composition-based stats.
Identities = 106/570 (19%), Positives = 181/570 (32%), Gaps = 49/570 (9%)
Query 63 NYIVWKTNHFTIPKE-QYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITII 121
+ W + I + I + S+ F A+ + + + +T+
Sbjct 29777 PRVTWFKDGVEIERRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNVSGSTKAEVTVK 29836
Query 122 SGLPPEKPKNLSCIVN-EGKKMRCEWDGGRETH--LETNFTLKSEWATHKFADCKAKRDT 178
P K N G+KM W+ T++ ++ + T + A + +
Sbjct 29837 VQDTPGKVVGPIRFTNITGEKMTLWWEAPLNDGCAPVTHYIIE-KRETSRLAWALIEDNC 29895
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALGK---VTSDHINFDPVYKVKPNPPHNLSVINSEE 235
+ + + A N G + SD + Y + P+ P S
Sbjct 29896 EALSYTAIKLITGNEYQFRISAVNKFGVGRPLESDPVVAQIQYTI-PDAPGVP--EPSNV 29952
Query 236 LSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ + LTWT P S I Y ++ R K ++ W ++ + S + F V L E
Sbjct 29953 TGNSITLTWTRPESDGGSEIQHYILERREKKSTRWVKVISKRPIS-ETRFKVTGLVEGNE 30011
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y F + G G S S P PS + + T TV L W
Sbjct 30012 YEFHVMAENAAGIGPASGISRLIKCR----EPVNPPSAPSVVKVTDTSKT-TVSLEW-AR 30065
Query 355 PPFEANGKILDYEVTLTR-----WKSHLQNYTVNATKLTVNL-TNDRYLATLTVRNLVGK 408
P F+ +I+ Y + + + W V +L + Y ++ N GK
Sbjct 30066 PVFDGGMEIIGYIIEMCKADLGDWHKVNTEPCVKTRYTVTDLQAGEEYKFRVSAVNGAGK 30125
Query 409 SDA----------AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT-TPRESVKKYILEW 457
D+ L+ P D A + L++ + P + W
Sbjct 30126 GDSCEVTGTIKAVDRLSAPELDIDANFKQTHIVRAGVSIRLFIAYQGRPTPTAV-----W 30180
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
D D T N ++ Y +TV +SI +K
Sbjct 30181 SKPDSNLSIRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGK-----KSITFTVKVL 30235
Query 518 -PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAVNVDSSHT 575
P + K V + A L WD P+ I +Y I R + V+ +
Sbjct 30236 DSPGPPGPITFKDVTRGSATLMWDA-PLLDGGARIHHYVIEKREASRRSWQVVSEKCTRQ 30294
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+S LT Y R++A + G + E
Sbjct 30295 ILKVSELTEGVPYYFRVSAENEYGVGEPYE 30324
Score = 149 bits (375), Expect = 5e-35, Method: Composition-based stats.
Identities = 110/634 (17%), Positives = 183/634 (29%), Gaps = 50/634 (8%)
Query 35 SPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDI 94
P ++ A + + W I I T +S T
Sbjct 22170 DPTIKDGLTVKAGDSIVLSAISILGKPLPKSSWSRAGKDIRPSDIAQITSTPTSSMLTVK 22229
Query 95 ASLNI---QLTCNILT-FGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
+ + T FG E++V + PP P +S + E + W
Sbjct 22230 YATRKDAGEYTITATNPFGTKEEHVKVSVLDVPGPPG-PIEISNVSAEKATL--TWTPPL 22286
Query 151 ETHLET--NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
E + L+ + T + D V + V A N GK
Sbjct 22287 EDGGSPIKAYVLE-KRETSRLLWTVVSEDIQACRHVVTKLIQGNEYLFRVSAVNHYGKGE 22345
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI-KSVIILKYNIQYRTKDAS 267
+ P S + ++W P+ I Y+++ R K
Sbjct 22346 PVQSEPVKMVDRFGPPGPPGKPEISNVTKNTATVSWKRPTDDGGSEITGYHVERREKKGL 22405
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
W + T + V L+ Y FR+ G G SD S P
Sbjct 22406 RW--VRATKTPVSDLRCKVTGLQEGNTYEFRVSAENRAGIGPPSDASNPVLMKDV-AYPP 22462
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKL 387
PS + D + ++ L W P ++ +I Y V + T L
Sbjct 22463 GPPSNAHVTDTT----KKSASLAW-GKPHYDGGLEITGYVVEHQKVGDDAWIKDTTGTAL 22517
Query 388 TV-------NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW 440
+ T ++Y ++ N G + AV+ + P +L A
Sbjct 22518 RITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPNVEIVEKEVAPDFELDAE------- 22570
Query 441 VEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY 500
+ T + + + AP +T W +++ + N +I Y
Sbjct 22571 LRRTLVVRAGLSIRIFVPIKGRPAPEVT-WTKDNINLKHRANIENTESFTLLIIPECNRY 22629
Query 501 ADG------PGSPESIKAYLKQAP---PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
G ++ P +R + K+ L WD LP+ I
Sbjct 22630 DTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWD-LPLIDGGSRI 22688
Query 552 RNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
NY + R + V Y ++ LT Y R+ A + G + E T
Sbjct 22689 TNYIVEKREATRKSYSTVTTKCHKCTYKVTGLTEGCEYFFRVMAENEYGVGEPTETT--E 22746
Query 611 PKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
P A EA + P L + T V + K
Sbjct 22747 PVRAS---EAPLPPDSLNIMDITKNTVSLAWPKP 22777
Score = 147 bits (371), Expect = 2e-34, Method: Composition-based stats.
Identities = 88/458 (19%), Positives = 145/458 (32%), Gaps = 59/458 (13%)
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILK 256
+ A+N G+ T+ N P PP +L V + S +L+W P I
Sbjct 17680 ITAKNKAGQKTA---NCRVKVMDAPGPPKDLKVSDITRGS--CRLSWKMPDDDGGDRIKG 17734
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y I+ +T D W+++ P + ++F V DL +Y FR+R G G ++
Sbjct 17735 YVIEKKTIDGKAWTKVNPNCGS---TTFVVPDLISEQQYFFRVRAENRFGIGPPAE---- 17787
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
+ R P TV L WK P + + Y V W
Sbjct 17788 -TIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKP-PKNDGGSPVTHYIVECLAWDPT 17845
Query 377 ---------LQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAAVLT----IPACDF 421
V + TV + Y + N G S + +
Sbjct 17846 GKKKEAWRQCNRRDVEELEFTVEDLIEGGEYEFRVKAVNEAGVSKPSATVGPVIVKDQTC 17905
Query 422 QATHPVMDLKAFPKDNMLWV------------EW--TTPRESVKKYILEWCVLSDKAPCI 467
+ + + + + W P++ K + + +K
Sbjct 17906 PPAIELKEFMEVEEGTDVNIVAKIKGVPFPTLTWFKAPPKKPDSKEPVVYDTHVNK---- 17961
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
Q D T + +++ Y IT V G S E L + P GP ++
Sbjct 17962 ---QVVDDTCTLVIPQSRRSDTGLYSIT--AVNNLGTASKEMRLNVLGRPGPPVGP-IKF 18015
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDT 586
+ + ++ L W P D I NY I R V+ + YT+ L
Sbjct 18016 ESISADQMTLSWLP-PKDDGGSKITNYVIEKREANRKTWVRVSSEPKECMYTIPKLLEGH 18074
Query 587 LYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVP 624
Y+ R+ A G E + P+ A+ P
Sbjct 18075 EYVFRIMAQNKYGIG---EPLDSEPETARNLFSVPGAP 18109
Score = 144 bits (364), Expect = 1e-33, Method: Composition-based stats.
Identities = 101/608 (17%), Positives = 180/608 (30%), Gaps = 84/608 (14%)
Query 41 HSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQ 100
++ V +K V + W P + ++ T + +
Sbjct 17920 GTDVNIVAKIK-------GVPFPTLTWFKAPPKKPDSKEPVVYDT-------HVNKQVVD 17965
Query 101 LTCNILTF--GQLEQNVYGITIISGL----------------PPEKPKNLSCIVNEGKKM 142
TC ++ + + +Y IT ++ L PP P + +M
Sbjct 17966 DTCTLVIPQSRRSDTGLYSITAVNNLGTASKEMRLNVLGRPGPPVGP--IKFESISADQM 18023
Query 143 RCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF-VNIEVWVE 199
W ++ TN+ ++ A K P C + +
Sbjct 18024 TLSWLPPKDDGGSKITNYVIEKREANRKTW--VRVSSEPKECMYTIPKLLEGHEYVFRIM 18081
Query 200 AENALGK---VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIIL 255
A+N G + S+ ++ V P P +V + S + + W P +
Sbjct 18082 AQNKYGIGEPLDSEPETARNLFSV-PGAPDKPTVSSVTRNS--MTVNWEEPEYDGGSPVT 18138
Query 256 KYNIQYRTKDASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
Y ++ + + W ++ P + S+ V L ++Y FR+ + G G S
Sbjct 18139 GYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLP 18198
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
S+ T D + + K+ +V L W P + KI Y V
Sbjct 18199 SDPV---TARDPVAPPGPPFPKVTDWT---KSSVDLEWSP-PLKDGGSKITGYIVEYKEE 18251
Query 374 KSHLQNYT----VNATKLTVNLTNDR--YLATLTVRNLVGKSDAAVLT--------IPAC 419
V TKL V + Y + N+ G + +T I +
Sbjct 18252 GKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNVAGVGEPGEVTDVIEMKDRIVSP 18311
Query 420 DFQATHPVMDLKAFPKDNML----WVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
D Q V D ++ +V P + W + P E
Sbjct 18312 DLQLDASVRDRIVVHAGGVIRIIAYVSGKPPP------TVTWSMNERALPQEAAI--ETT 18363
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
+ + + N S + ++ G ++I + P G + + +
Sbjct 18364 AISSSMVIKNCQRSHQGVYSLLAKNEGGERK-KTIIVDVLDVPGPVGIPFLSDNLTNDSC 18422
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
L W P D I NY I R T V + T+ L Y R+AA
Sbjct 18423 KLTWFS-PEDDGGSPITNYVIQKREADRRAWTPVTYTVTRQNATVQGLIQGKSYFFRIAA 18481
Query 595 YTDEGGKD 602
G
Sbjct 18482 ENSIGMGP 18489
Score = 142 bits (357), Expect = 8e-33, Method: Composition-based stats.
Identities = 101/581 (17%), Positives = 182/581 (31%), Gaps = 52/581 (9%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNIL-----TFGQ 110
I W + + + + TA+S T I + + G
Sbjct 26123 PVIGRPRPKISWVKDGEPLKQTTRVNVEETATS-TILHIKESSKDDFGKYSVTATNSAGT 26181
Query 111 LEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHK 168
+N+ I + PP P + + + W+ T +N+ ++ T
Sbjct 26182 ATENLSVIVLEKPGPPVGPVKFDEVSADF--VVISWEPPAYTGGCQISNYIVEKRDTTTT 26239
Query 169 FADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS-DHINFDPVYKVK-PNPPH 226
+ T+ + + + AEN GK T D Y K P PP
Sbjct 26240 NWQMVSATVARTTIKISKLKTG-TEYQFRIFAENRYGKSTPLDSKPVVVQYPFKEPGPPG 26298
Query 227 NLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
V + + + W P + + Y+++ + K++ W + + F
Sbjct 26299 TPFVTSI--SKDQMLVQWHEPVNDGGSKVTGYHLEQKEKNSILW--VKLNKIPIQDTKFK 26354
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
L EY FR+ G G S SE D P + + +
Sbjct 26355 TTGLDEGLEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIVITRN-------- 26406
Query 346 TVQLVWKTLPPFEANGKILDYEV-----TLTRW-KSHLQNYTVNATKLTVNLTNDRYLAT 399
+V L WK P ++ KI Y V RW K+ N +T + + RY
Sbjct 26407 SVTLKWKK-PVYDGGSKITGYIVEKKDLPDGRWMKASFTNVVETEFTVTGLVEDQRYEFR 26465
Query 400 LTVRNLV------GKSDAAVL---TIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV 450
+ RN +S A+ I A + D+ +E + +
Sbjct 26466 VIARNAADNFSEPSESSGAITARDEIDAPNASLDPKYRDVIIVHAGETFVLEADIRGKPI 26525
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN---LAESKCYLITVTPVYADGPGSP 507
I W ++ + T+ +T L + Y + ++ V P
Sbjct 26526 PDII--WSKDGNELEETAARMEIKSTLQKTTLIVKDCIRTDGGQYTLKLSNVGGTKTI-P 26582
Query 508 ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NET 566
++K + PP ++ V + L W+ P+ I +Y I R + T
Sbjct 26583 ITVKVLDRPGPPEGP--LKVTGVTAEKCYLAWNP-PLQDGGASISHYIIEKRETSRLSWT 26639
Query 567 AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
V+ + Y ++ L Y+ R+ A G + E
Sbjct 26640 QVSNEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEALESE 26680
Score = 141 bits (355), Expect = 1e-32, Method: Composition-based stats.
Identities = 102/590 (17%), Positives = 177/590 (30%), Gaps = 89/590 (15%)
Query 70 NHFTIPKEQYTIINRTASSVTFT----DIASLNIQLT----CNILTFGQLEQNVYGITII 121
N P + Y I R AS + + L+ ++T I F +N +G
Sbjct 28092 NDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFG---- 28147
Query 122 SGLP------------PEKPKNLSCIVNEGKKMRCEW-DGGRETHLET-NFTLKSEWATH 167
G+P P P+ L + W + ++ +++
Sbjct 28148 VGVPAETKEGVKITEKPSPPEKLGVTSVSKDSVSLSWLKPEHDGGSRIIHYVVEALEKGQ 28207
Query 168 K-FADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH 226
K + C + T + + V AEN G + + K + PP
Sbjct 28208 KTWVKCAVVKTTHHVVSGLRES---HEYFFRVFAENQAGLSDPRELLLPVLIKDQLEPPE 28264
Query 227 -----------------NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW 269
NL V + K+T + + LK +++ T+ +
Sbjct 28265 IDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVT----LSRDGVPLKATMRFNTEITAEN 28320
Query 270 SQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
I +++ +T Y I G ++ I DRP
Sbjct 28321 LTINLKESVTTD----------AGRYE--ITAANSSGT------TKTFINIIVLDRPGPP 28362
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR-----WKSHLQNYTVNA 384
D + +V L W+ P ++ + +Y V W
Sbjct 28363 TGPVAISDIT----EESVTLKWEP-PKYDGGSHVTNYIVLKRETSTAVWSEVSATVARTM 28417
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSD---AAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
K+ T + Y + N G SD + + + P + + V
Sbjct 28418 IKVMKLTTGEEYQFRIKAENRFGISDHIDSVCVVVKLPYTTPGPPSTPWVSNVTRESITV 28477
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT--YLRGNLAESKCYLITVTPV 499
W P + + + L K WQ+ + + RT + ++ Y V
Sbjct 28478 GWHEPVSNGGSAVTGY-HLEMKDRNSILWQKANKMIIRTTHFKVTTISAGLIYEFRVYAE 28536
Query 500 YADGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
A G G P + L VR + KN L W Q P I Y +
Sbjct 28537 NAAGIGKPSHPSEPVLAIDACEPPRNVRITDISKNSVNLSWQQ-PAFDGGSKITGYIVER 28595
Query 559 RTI-IGNETAVNV-DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
R + G T + + T++T+S LT ++ Y R+ A G P
Sbjct 28596 RDLPDGRWTKASFTNVIETQFTVSGLTQNSQYEFRVFARNAVGSVSNPSE 28645
Score = 139 bits (349), Expect = 7e-32, Method: Composition-based stats.
Identities = 103/537 (19%), Positives = 171/537 (32%), Gaps = 45/537 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHKFADCKAKRDTPTSC 182
PP P +S I E + +W+ + TN+ + + T + +
Sbjct 28361 PPTGPVAISDITEE--SVTLKWEPPKYDGGSHVTNYIV-LKRETSTAVWSEVSATVARTM 28417
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYK----VKPNPPHNLSVINSEELSS 238
+ ++AEN G SDHI+ V P PP V N S
Sbjct 28418 IKVMKLTTGEEYQFRIKAENRFGI--SDHIDSVCVVVKLPYTTPGPPSTPWVSNVTRES- 28474
Query 239 ILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ + W P S + Y+++ + +++ W + + F V + Y F
Sbjct 28475 -ITVGWHEPVSNGGSAVTGYHLEMKDRNSILWQKANKMIIR--TTHFKVTTISAGLIYEF 28531
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
R+ G G S SE I + P D S +V L W+ P F
Sbjct 28532 RVYAENAAGIGKPSHPSEPVLAIDA----CEPPRNVRITDISKN----SVNLSWQQ-PAF 28582
Query 358 EANGKILDYEVTLT-----RWKSHL-QNYTVNATKLTVNLTNDRYLATLTVRNLVGK--S 409
+ KI Y V RW N ++ N +Y + RN VG +
Sbjct 28583 DGGSKITGYIVERRDLPDGRWTKASFTNVIETQFTVSGLTQNSQYEFRVFARNAVGSVSN 28642
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES-----VKKYILEWCVLSDKA 464
+ V+ C PV+DL + + + T+ + + +EW +
Sbjct 28643 PSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPEPTIEWYKDDKEL 28702
Query 465 PCITDWQQEDGTVHRTYLRGNLAE--SKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
E+ T + L + S Y + + A G S L + P G
Sbjct 28703 QTNALVCVENSTDLASILIKDANRLNSGSYELKLR--NAMGSASATIRVQILDKPGPPGG 28760
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNVDSSHTEYTLSS 581
P + K V + L W P D I +Y + R + V + T +
Sbjct 28761 P-IEFKTVTAEKITLLWRP-PADDGGAKITHYIVEKRETSRVVWSMVAENLEECIVTTTK 28818
Query 582 LTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
+ Y+ R+ A G + E K A +P ++ V
Sbjct 28819 IIKGNEYVFRVRAVNKYGIGEPLESEPVVAKNAFVTPGPPSIPEVTKITKNSMTVVW 28875
Score = 139 bits (349), Expect = 8e-32, Method: Composition-based stats.
Identities = 87/411 (21%), Positives = 140/411 (34%), Gaps = 34/411 (8%)
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNI 259
EN+ G ++ P PP NL+V E + L W P + Y I
Sbjct 25887 ENSSGSKSA---FVTVKVLDTPGPPQNLAVK--EVRKDSVLLVWEPPIIDGGAKVKNYVI 25941
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
R ++ + + ++SF V++L Y FR+ E G G ++ S+
Sbjct 25942 DKRESTRKAYANVSSK---CNKTSFRVENLTEGAIYYFRVMAENEFGVGVPTETSDAVKA 25998
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL----TRWKS 375
P P D S T L+W+ P + +IL Y V + T S
Sbjct 25999 ----SEPPSPPGKVTLTDVSQTSAS----LMWEK-PEHDGGSRILGYVVEMQPKGTEKWS 26049
Query 376 HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA-----CDFQATHPVMDL 430
+ V ++ + Y + N GKSD VL IP + +
Sbjct 26050 VVAESKVCNAVVSGLSSGQEYQFRVKAYNEKGKSDPRVLGIPVIAKDLTIQPSFKLPFNT 26109
Query 431 KAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAES 489
+ L +E + I W + T + T T L ++
Sbjct 26110 YSVQAGEDLKIE-IPVIGRPRPKI-SWVKDGEPLKQTTRV-NVEETATSTILHIKESSKD 26166
Query 490 KCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
+VT + G + L++ P GP V+ +V + V+ W+ P
Sbjct 26167 DFGKYSVTATNSAGTATENLSVIVLEKPGPPVGP-VKFDEVSADFVVISWEP-PAYTGGC 26224
Query 550 FIRNYTIFYR-TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
I NY + R T N V+ + T +S L + T Y R+ A G
Sbjct 26225 QISNYIVEKRDTTTTNWQMVSATVARTTIKISKLKTGTEYQFRIFAENRYG 26275
Score = 137 bits (344), Expect = 3e-31, Method: Composition-based stats.
Identities = 95/578 (16%), Positives = 172/578 (30%), Gaps = 35/578 (6%)
Query 57 YFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVY 116
Y + W + + I T +T + N+Q + + N +
Sbjct 32441 YIGRPVPAMTWFHGQKLLQNSEKITIENTEH---YTHLVMKNVQRKTHAGKYKVQLSNAF 32497
Query 117 GI-----TIISGLPPEKPKNLSCIVNEGKK-MRCEWDGGRETHLE--TNFTLKSEWATHK 168
G + P+KP I K + W + TN+ ++ A
Sbjct 32498 GTVDATLDVEIQDKPDKPTGPIVIEALLKNSVVISWKPPADDGGSWITNYVVEKCEAKEG 32557
Query 169 FADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK-----PN 223
+ + V A+N G S+ + + +K P
Sbjct 32558 AEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGI--SEPLEVASIVIIKSPFEKPG 32615
Query 224 PPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P ++ + W P S I Y ++ R K + W + E+ +
Sbjct 32616 VPGKPTITAV--TKDSCVVAWKPPASDGGAKIRNYYLERREKKQNKWIAVTTEEIR--ET 32671
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
F+VQ+L EY FR++C G+ WS+ SE + + D P +AP F ++ + +
Sbjct 32672 VFSVQNLIEGLEYEFRVKCENLGGESEWSEISEPVTPKS--DVPIQAPHFKEELRNLNVR 32729
Query 343 GYRTVQLVWK--TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN--DRYLA 398
LV K P E+ K +Q + +L + D +
Sbjct 32730 YQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVY 32789
Query 399 TLTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
+ N G A++ + + A V P ++
Sbjct 32790 QVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVIT 32849
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
W D +Q + + N E K V ++++ +
Sbjct 32850 WQKGQDLIDNNGHYQVIVTRSFTSLVFSNGVERKDAGFYVVCAKNRFGIDQKTVELDVA- 32908
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
P V+ V ++ L W + P + NY + + T
Sbjct 32909 DVPDPPRGVKVSDVSRDSVNLTWTE-PASDGGSKVTNYIVEKCATTAERWLRVGQARETR 32967
Query 577 YTLSSLTSDTLYMVRMAAYTDEG--GKDGPEFTFTTPK 612
YT+ +L T Y R+ A G P T +
Sbjct 32968 YTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTVTKE 33005
Score = 134 bits (338), Expect = 1e-30, Method: Composition-based stats.
Identities = 97/611 (16%), Positives = 183/611 (30%), Gaps = 50/611 (8%)
Query 55 MDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLN------IQLTCNILTF 108
+ Y I W + + + +Y ++T + +T + S + N +
Sbjct 29374 LPYKGKPKPSISWLKDGLPLKESEYVRFSKTENKITLSIKNSKKEHGGKYTVILDNAVCR 29433
Query 109 GQLEQNVYGITIISGLPPEKPKN-LSCIVNEGKKMRCEWD-GGRETHLE-TNFTLKSEWA 165
+ I G PP KPK + + WD + E T ++++ A
Sbjct 29434 NSFPITI----ITLG-PPSKPKGPIRFDEIKADSAIMSWDIPEDDGGGEITCYSIEKREA 29488
Query 166 THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS--DHINFDPVYKVKPN 223
+ + + V + V AEN G +I P
Sbjct 29489 SQTNWK-MVCSSVARTTFKVSNLVKDSEYQFRVRAENRYGVSEPLASNIIVAKHQFRIPG 29547
Query 224 PPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
PP + N S + LTW P + ++++ + +++ W ++ +
Sbjct 29548 PPGKPVIYNV--TSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQRVNTSPISG--R 29603
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
+ L +Y FR+ G SD S+ T P P ID +
Sbjct 29604 EYRATGLIEGLDYQFRVYAENSAGLSSPSDPSKF----TLAVSPVDPPGTPDYIDVTRE- 29658
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL-----QNYTVNATKLTVNLTNDRYL 397
T+ L W P + KI+ Y + + + + +T DRY
Sbjct 29659 ---TITLKWNP-PLRDGGSKIVAYSIEKRQGSDRWVRCNFTDVSECQYTVTGLSPGDRYE 29714
Query 398 ATLTVRNLVGK-SDAAVLT--IPACDFQATHPVM------DLKAFPKDNMLWVEWTTPRE 448
+ RN VG S + + I D V D + L ++
Sbjct 29715 FRIIARNAVGTISPPSQSSGLIMTRDENVPPTVEFGPEYFDGLVIKSGDSLRIKALVQGR 29774
Query 449 SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE 508
V + + W + + + D + + + TV G E
Sbjct 29775 PVPR--VTWFKDGVEIERRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNVSGSTKAE 29832
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETA 567
+ ++ P +R + + L W+ P++ + +Y I R
Sbjct 29833 -VTVKVQDTPGKVVGPIRFTNITGEKMTLWWEA-PLNDGCAPVTHYIIEKRETSRLAWAL 29890
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
+ + YT L + Y R++A G E + +A VP
Sbjct 29891 IEDNCEALSYTAIKLITGNEYQFRISAVNKFGVGRPLESDPVVAQIQYTIPDAPGVPEPS 29950
Query 628 AFLLTTLLGVL 638
++
Sbjct 29951 NVTGNSITLTW 29961
Score = 134 bits (338), Expect = 2e-30, Method: Composition-based stats.
Identities = 93/544 (17%), Positives = 158/544 (29%), Gaps = 64/544 (12%)
Query 103 CNILTFGQLEQNVYGITIISG-----------LPPEKPKNLSCIVNEGKKMRCEWD-GGR 150
N F +N YG PP PK+L + + ++ W+ R
Sbjct 19165 GNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDR 19224
Query 151 ETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS 209
+ T + ++ + K K K C V V+AEN +G
Sbjct 19225 DGGSPITGYLVEYQEEGDK-DWIKFKTVKNLDCVVTGLQQGK-TYRFRVKAENIIGLGLP 19282
Query 210 DHINFDPVYKVKPNPPH-NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST 268
D + K PP L V E L T P+ I+ +
Sbjct 19283 D-TTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPA---------IIRGVPVPTAK 19332
Query 269 WSQIPPEDTASTRSSF---------TVQD-LKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
W+ E + T+++ L+ T +++ G A
Sbjct 19333 WTTDGTEIKTDDHYTVETDSFSSVLTIKNCLRKDTG-EYQLTVSNAAGTKT------VAV 19385
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW-KSHL 377
+T D P +D + + + W+ P + +++Y V K
Sbjct 19386 HLTVLDVPGPPTGPINILDVT----PEYMTISWQP-PKDDGGSPVINYIVEKQDTRKGTW 19440
Query 378 QNYTVNATKLTVNLT----NDRYLATLTVRNLVGKSDA--AVLTIPACDFQATHPVMDLK 431
+ ++KL + + Y+ + N +G ++ T+ F P
Sbjct 19441 GVVSAGSSKLKLKVPHLQKGCEYVFRVKAENKMGVGPPLDSIPTVAKHKFSPPSPPGKPV 19500
Query 432 AFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
+N V WT P+ I + V + + + L E
Sbjct 19501 VTDITENAATVSWTLPKSDGGSPITGYYVERREITGKWVRVNKTPIADLKFRVTGLYEGN 19560
Query 491 CYLITVTPVYADGPGSPE----SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDV 546
Y V G +P IKA PP + K K A L W + P+
Sbjct 19561 TYEFRVFAENLAGLSNPSPSSDPIKACRPIKPPGPPINPKLKDKSKESADLVWTK-PLSD 19619
Query 547 QNGFIRNYTIFYR-TIIGNETAVNVDS--SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
I Y + Y+ +N D + + L Y R+ A G +
Sbjct 19620 GGSPILGYVVEYQKPGTAQWDRINKDELIRQCAFRVPGLIEGNEYRFRIRAANIVGEGEP 19679
Query 604 PEFT 607
E
Sbjct 19680 RELA 19683
Score = 134 bits (338), Expect = 2e-30, Method: Composition-based stats.
Identities = 110/804 (14%), Positives = 217/804 (27%), Gaps = 124/804 (15%)
Query 33 PESPVVQLHS-----NFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTAS 87
P PV+ + + N + K + A K + + + + + +
Sbjct 28547 PSEPVLAIDACEPPRNVRITDISKNSVNLSWQQPAFDGGSKITGYIVERR--DLPDGRWT 28604
Query 88 SVTFTDIASLNIQLTC----NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
+FT++ ++ + F +N G P E ++CI +
Sbjct 28605 KASFTNVIETQFTVSGLTQNSQYEFRVFARNAVG---SVSNPSEVVGPITCIDSY----- 28656
Query 144 CEWDGGRETHLETNFTLKSEWATHKFADCKA---------------------------KR 176
GG L +T ++ +A +
Sbjct 28657 ----GGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPEPTIEWYKDDKELQTNALVCVEN 28712
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
T + + + ++ NA+G ++ KP PP +
Sbjct 28713 STDLASILIKDANRLNSGSYELKLRNAMGSASAT---IRVQILDKPGPPGGP-IEFKTVT 28768
Query 237 SSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+ + L W P+ I Y ++ R WS + ++ + EY
Sbjct 28769 AEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVAENLEECIVTTTKIIK---GNEY 28825
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
VFR+R + + G G + SE + P ++ ++ +VW P
Sbjct 28826 VFRVRAVNKYGIGEPLE-SEPVVA--KNAFVTPGPPSIPEVT---KITKNSMTVVWD-RP 28878
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNAT------KLTVNLTNDRYLATLTVRNLVGKS 409
+ +I Y + KS + T K+T N Y + N G
Sbjct 28879 TVDGGSEINGYFLERRDKKSLAWLKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGVG 28938
Query 410 DAAVLTIP----ACDFQATHPVMDLKAFPKDNMLWVEWTTP----RESVKKYILEWCVLS 461
+ + P A + + + W+ P V Y++E +
Sbjct 28939 PFSEPSDFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSDVTGYVVE--MKQ 28996
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
T Y+ NL Y V+ V G G P ++ + +
Sbjct 28997 GDEEEWTIVSTRGEVRTTEYVVSNLKPGVNYYFQVSAVNCAGQGEPITMTEPAQAKDVLE 29056
Query 522 GPTVRTKKVGKNEAVLEWDQ-----------LPVDVQNGFIRNYTIFYRTII---GNETA 567
P + + + + + P T+ +R G++T
Sbjct 29057 EPEIDLDVALRTSVIAKAGEDVQLLIPFKGRPPP----------TVTWRKDEKNLGSDTR 29106
Query 568 VNVDSSHTE--YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPV 625
++ ++ + + +T + + G + + V V
Sbjct 29107 YSIQNTDSSSLLVIPQVTRNDTGKYILTIENGVGQPKSSTVSVKVLDTPAACQKLQVKHV 29166
Query 626 CLA---------FLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF 676
L + + + KRD K+ W V K +
Sbjct 29167 SLGTVTLLWDPPLIDGGSPIINYVIEKRDATKRT-WSVV--SHKCSGTSFKVTDLSEKTP 29223
Query 677 N----SKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSS 732
+ G + + A P DL D K + + GGS
Sbjct 29224 FFFRVLAENEIGIGEPCETTEPVKAAEVPAPI-RDLSMKDSTKTSVVLSWTKPDFDGGSI 29282
Query 733 CMSSSRPSISSSDENESSQNTSST 756
++ S S T
Sbjct 29283 ITDYLVERKGKGEQAWSHAGISKT 29306
Score = 133 bits (334), Expect = 4e-30, Method: Composition-based stats.
Identities = 97/610 (16%), Positives = 180/610 (30%), Gaps = 86/610 (14%)
Query 40 LHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNI 99
+ + V EK M + +K +P ++Y + R ++V ++ + ++
Sbjct 16106 IGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGIVPDKEYVLRVRAVNAVGVSEPSEISE 16165
Query 100 QLTCNILTFGQLEQ-NVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG-GRETHLETN 157
+ + I +I G P + W G+E
Sbjct 16166 NVVAKDPDCKPTIDLETHDIVVIEGEKLNIPVPFRAVPVP----TVSWHKDGKEVKASDR 16221
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPV 217
T+K++ + A + P S D + + EN LG T+ +
Sbjct 16222 LTMKNDHIS-------AHLEVPKSVHADAGV-----YTITL--ENKLGSATAS---INVK 16264
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPED 276
P P ++ + S KLTW P IL Y ++ R T+ +
Sbjct 16265 VIGLPGPCKDIKASDI--TKSSCKLTWEPPEFDGGSPILHYVLERREAGRRTYIPVM--- 16319
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ + S+TV+DL P EY FR++ + + G G + + + P
Sbjct 16320 SGENKLSWTVKDLIPNGEYFFRVKAVNKIGGGEYIELKNPVIAQDPKQPPDPPVDVEV-- 16377
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEV--------TLTRWKSHLQNYTVNATKLT 388
H + + + WK P ++ KI+ Y + R HL V
Sbjct 16378 ---HNPTAKAMTITWKP-PLYDGGSKIMGYIIEKITKGEDRWKRCNEHL--VPVLTYTAK 16431
Query 389 VNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM-------------------D 429
Y + N G + + T P
Sbjct 16432 GLEEGKEYQFRVRAENAAGIGEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDAT 16491
Query 430 LKAFPKDNMLWV-------------EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
+ P + W+ P K E S
Sbjct 16492 ISGSPYPTITWIKDENVIVPEEIKKRAAPPVRRKKGEAEEEEPFSLPLTERLSINNSKQG 16551
Query 477 VHRTYLRGNLAESK-CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
+ +R +L Y+I V + P + + K+
Sbjct 16552 ESQLRIRDSLRPDHGQYMIKVENDHGVAKAPCSVSVLDT----PGPPINFVFEDIRKDSV 16607
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH---TEYTLSSLTSDTLYMVRM 592
+ +W+ P+D I NYT+ + ++ V +S +Y+++ L Y+ R+
Sbjct 16608 LCKWEP-PLDDGGSEIINYTLEKKDKTKPDSDWIVITSTLRNCKYSVTKLIEGKEYLFRV 16666
Query 593 AAYTDEGGKD 602
A G
Sbjct 16667 RAENRFGPGP 16676
Score = 132 bits (332), Expect = 7e-30, Method: Composition-based stats.
Identities = 94/614 (15%), Positives = 189/614 (31%), Gaps = 47/614 (8%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNV 115
+ + WK + + + + + + T + + + L ++
Sbjct 27206 PFKGRPQATVAWKKDGQVLRETTRVNVASSKTVTTLSIKEASREDVGTYELCVSNTAGSI 27265
Query 116 YG-ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR-ETHLE-TNFTLKSEWATHKFADC 172
IT+I P P + + W+ + + +N+ ++ T
Sbjct 27266 TVPITVIVLDRPGPPGPIRIDEVSCDNVSISWNPPEYDGGCQISNYIVEKRETTSTTWQV 27325
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT--SDHINFDPVYKVKPNPPHNLSV 230
++ TS + T + V AEN GK + P PP V
Sbjct 27326 VSQAVARTSIKIVRLTTG-SEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKV 27384
Query 231 INSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
+++ S + ++W P + ++ Y+++Y+ + + WS+ A T+ V L
Sbjct 27385 VHA--TKSTMVVSWQVPVNDGGSQVIGYHLEYKERSSILWSKANKVLIADTQM--KVSGL 27440
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
Y +R+ G G S E D P + ++V L
Sbjct 27441 DEGLMYEYRVYAENIAGIGKCSKACEPVPARDPCDPPGQPE--------VTNITRKSVSL 27492
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQ------NYTVNATKLTVNLTNDRYLATLTVR 403
W + P ++ KI Y V N ++T + RY + R
Sbjct 27493 KW-SKPRYDGGAKITGYIVERRELPDGRWLKCNFTNVQETYFEVTELTEDQRYEFRVFAR 27551
Query 404 NLVGK----SDAAVLTIPACDFQATHPVMDLK-----AFPKDNMLWVEWTTPRESVKKYI 454
N S++ D +A +MD+K +L + + +
Sbjct 27552 NAADSVSEPSESTGPITVKDDVEAPRIMMDVKFRDVIIVKAGEVLKINADIAGRPLP--V 27609
Query 455 LEWCVLSD--KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
+ W + T+ D T T ++ Y++T+ V + K
Sbjct 27610 ISWAKDGVEIEERAKTEIVSTDYTTTLTVKDCVRRDTGQYVLTLKNVAGTRT-MAVNCKV 27668
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVD 571
K PP+ + + + L W + P + I Y + R T +
Sbjct 27669 LDKPGPPAGP--LEINGLTAEKCSLSWGR-PQEDGGADIDYYIVEKRETSRLAWTICEAE 27725
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLL 631
T ++ L Y+ R+ G + P + + P L
Sbjct 27726 LRTTSCKVTKLLKGNEYIFRVTGVNKYGVGE-PLESMAVKALDPFTTPSP--PTSLEITS 27782
Query 632 TTLLGVLFCFNKRD 645
T + C+++ +
Sbjct 27783 VTKDSMTLCWSRPE 27796
Score = 130 bits (327), Expect = 3e-29, Method: Composition-based stats.
Identities = 104/628 (17%), Positives = 185/628 (29%), Gaps = 67/628 (11%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
I+ + + S FT + A + WK + + I T T
Sbjct 30441 ITNQLITCKAGSTFTI-------DVPISGRPAPKVTWKLEEMRLKETDRMSIATTKDRTT 30493
Query 91 FT-----DIASLNIQLTC-NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRC 144
T S LT N V I P P +S + E
Sbjct 30494 LTVKDSMRGDSGRYFLTLENTAGVKTFTITVVVIGRPG--PVTGPIEVSSVSAE--SCVL 30549
Query 145 EWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN 202
W ++ TN+ ++ + T V + T Y V +EN
Sbjct 30550 SWTEPKDDGGTEITNYIVEKRESGTTAWQLINSSVKRTQIKVTHLTKYK-EYCFRVSSEN 30608
Query 203 ALGKVTSDHINFDPVYK----VKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKY 257
G S + P+ V P+ P V + ++ W P I+ Y
Sbjct 30609 RFGV--SKPLESVPIVAEHPFVPPSAPTRPEVYYVSANAMSIR--WEEPYHDGGSKIVGY 30664
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
++ + ++ W + ++ V L EY FR + G S+ S
Sbjct 30665 WVEKKERNTILW--VKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPI 30722
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY--------EVT 369
D P + TV L+W + P ++ K++ Y EV
Sbjct 30723 MAQNPVDPPGRPE--------VTDVTRSTVSLIW-SAPVYDGGSKVVGYIIERKPVSEVG 30773
Query 370 LTRW-KSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG----KSDAAVLTIPACDFQAT 424
RW K + + N +T D Y + +N G S++ ++
Sbjct 30774 DGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPP 30833
Query 425 HPVMD------LKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
+D L + L ++ + I+ + C Q G
Sbjct 30834 KAELDARLQGDLVTIRAGSDLVLD-AAVGGKPEPKIIWTKGDKELDLCEKISLQYTGKRA 30892
Query 479 RTYLRG-NLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVL 537
++ + ++S Y +TV S+ + + P + +V + + L
Sbjct 30893 TAVIKYCDRSDSGKYTLTVKNASGT---KSVSVMVKVLDS-PGPCGKLTVSRVTEEKCTL 30948
Query 538 EWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
W LP + I +Y + R N V + Y ++ L + Y R+ A
Sbjct 30949 AWS-LPQEDGGAEITHYIVERRETSRLNWVIVEGECLTASYVVTRLIKNNEYTFRVRAVN 31007
Query 597 DEGGKDGPEFTFTTPKFAQGEIEAIVVP 624
G E + + +P
Sbjct 31008 KYGLGVPVESEPIVARNSFTIPSQPGIP 31035
Score = 127 bits (319), Expect = 3e-28, Method: Composition-based stats.
Identities = 78/442 (18%), Positives = 145/442 (33%), Gaps = 46/442 (10%)
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNI 259
EN GK T + PN P + + + ++++W P+ IL Y +
Sbjct 31999 ENKCGKKT---VYIKVKVIGSPNTPEGP-LEYDDIQARSVRVSWRPPADDGGADILGYIL 32054
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ R + W I D+ +S V+ LK EY FR+ + G E
Sbjct 32055 ERREVPKAAWYTI---DSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVIP 32111
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR-----WK 374
T + P + +D + + +V L W + P + ++ Y + W
Sbjct 32112 KTPLNPPEPPSNPPEVLDVTKS----SVSLSW-SRPKDDGGSRVTGYYIERKETSTDKWV 32166
Query 375 SHLQNYTVNATKLTVNLTNDR-YLATLTVRNLVGKSDAAVLTIPAC-----DFQATHPVM 428
H + L D Y + +N VG S+ + + P D + +
Sbjct 32167 RHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGEL 32226
Query 429 DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV--HRTYLRGNL 486
++ + KD+ + ++W P K IL + V + W++ + R + G L
Sbjct 32227 EILSISKDS-VTLQWEKPECDGGKEILGYWVEYR-QSGDSAWKKSNKERIKDRQFTIGGL 32284
Query 487 AESKCYLITVTPVYADGPGSP-ESIKAYLKQAPPSKGPTVRTKKVGKN---------EAV 536
E+ Y V G P + + + + P VR +
Sbjct 32285 LEATEYEFRVFAENETGLSRPRRTAMSVKTKLTSGEAPGVRKEMADVTTKLGEAAQLSCQ 32344
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
+ LP I+ Y I + ++ D T+ + + + A
Sbjct 32345 IVGRPLP------DIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTDEQEDEGVYTCVATN 32398
Query 597 DEGGKDGPEFTF--TTPKFAQG 616
+ G + P+F G
Sbjct 32399 EVGEVESSSKLLLQAAPQFHPG 32420
Score = 126 bits (316), Expect = 6e-28, Method: Composition-based stats.
Identities = 93/622 (15%), Positives = 171/622 (27%), Gaps = 86/622 (14%)
Query 23 ELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTII 82
E+ Y++ + P++ S V K +A W T K + +
Sbjct 21586 EVSKDSAYVTWDPPIIDGGSPIINYVVEK--------RDAERKSWSTVTTECSKTSFRVS 21637
Query 83 NRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKM 142
N F + + N G + + + P +L +
Sbjct 21638 NLEEGKSYFFRVFAE------NEYGIGDPGETRDAV--KASETPGPVVDLKALAITKSSC 21689
Query 143 RCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
W R T + + +K+ S V A
Sbjct 21690 TIGWKKPRSDGGSRITGYVVDFLTEENKWQRVMKSLSLQYST---KDLKEGKEYTFRVSA 21746
Query 201 ENALGKVTSDHINFDPVYKVKPNPP---------------HNLSVINSEELSSILKLTWT 245
EN G+ T I V N + + ++W
Sbjct 21747 ENENGEGTPSEIVVVAKDDVVAPDLDLKDLPDLCYLAKENSNFRLKIPIKGKPAPSVSWK 21806
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP--FTEYVFRIRCMK 303
+T +++ E TA + V D + +Y ++ +
Sbjct 21807 KGEDP---------------LATDTRVSVESTAVNTT-LVVYDCQKSDAGKYTITLKNVA 21850
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
+G S + P+ F + L W P + +I
Sbjct 21851 GTKEGTLS-----IKVVGKPGIPTGPIKF-------DEVTAEAMTLKWGP-PKDDGGSEI 21897
Query 364 LDYEVTLT-----RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG-----KSDAAV 413
+Y + +W + ++T Y ++ N G KS+ V
Sbjct 21898 TNYVLEKRDSVNNKWVTCASAVQKTTFRVTRLHEGIEYTFRVSAENKYGVGEGLKSEPIV 21957
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQE 473
P D P ++ D+ + + WT P+++ I + + K W++
Sbjct 21958 AKHP-FDVPDAPPPPNIVDVRHDS-VSLTWTDPKKTGGSPITGYHIEF-KERNSLLWKRA 22014
Query 474 DGTVHRTY--LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT-VRTKKV 530
+ T R L E Y V + G G P + P P V
Sbjct 22015 NKTPIRMKDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVISV 22074
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLY 588
+N L W + D + + Y + R + A +V+ +T++ L Y
Sbjct 22075 TRNSVTLIWTEPKYDGGH-KLTGYIVEKRDLPSKSWMKANHVNVPDCAFTVTDLVEGGKY 22133
Query 589 MVRMAAYTDEGGKDGPEFTFTT 610
R+ A G P + T
Sbjct 22134 EFRIRAKNTAGAISAPSESTGT 22155
Score = 124 bits (310), Expect = 3e-27, Method: Composition-based stats.
Identities = 86/525 (16%), Positives = 154/525 (29%), Gaps = 72/525 (14%)
Query 137 NEGKKMRCEWDGGRETH---LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN 193
K M W + K ++ C + P
Sbjct 16380 PTAKAMTITWKPPLYDGGSKIMGYIIEKITKGEDRWKRCN-EHLVPVLTYTAKGLEEGKE 16438
Query 194 IEVWVEAENALGKVTSDHINFDPVYKVKPNPP-----HNLSVINSEEL--------SSIL 240
+ V AENA G + P +L V +E+ S
Sbjct 16439 YQFRVRAENAAGIGEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDATISGSPYP 16498
Query 241 KLTWTNPSIKSVIILKYNIQYR----------------TKDASTWSQIPPEDTASTRSSF 284
+TW ++VI+ + I+ R ++ ++ S
Sbjct 16499 TITWIK--DENVIVPE-EIKKRAAPPVRRKKGEAEEEEPFSLPLTERLSINNSKQGESQL 16555
Query 285 TVQD-LKPF-TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
++D L+P +Y+ ++ E+ G + T P +F ++
Sbjct 16556 RIRDSLRPDHGQYMIKV----ENDHGVAKAPCSVSVLDT----PGPPINFVFE-----DI 16602
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT-------KLTVNLTNDR 395
+V W+ P + +I++Y + ++ V + +T +
Sbjct 16603 RKDSVLCKWEP-PLDDGGSEIINYTLEKKDKTKPDSDWIVITSTLRNCKYSVTKLIEGKE 16661
Query 396 YLATLTVRNLVGKSDAAV---LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
YL + N G V L P + N + V+W P+++
Sbjct 16662 YLFRVRAENRFGPGPPCVSKPLLAKDPFEPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP 16721
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYL--RGNLAESKCYLITVTPVYADGPG---SP 507
IL + L + T W + + T+ + L E Y+ V A GPG P
Sbjct 16722 -ILGYW-LEKREVNSTHWSRVNKTLLSSLKTKVDGLLEGLTYVFRVCAENAAGPGKFSPP 16779
Query 508 ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-- 565
K P P R LEW+ P G I Y + + + NE
Sbjct 16780 SDPKTARDPISPPGPPVPRVADTSSTTIELEWEP-PAFNGGGEIMGYFVDKQLVGTNEWS 16838
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
++T+ + Y +R++A G E T
Sbjct 16839 RCTEKMIKVRQFTVKEIREGADYKLRVSAVNAAGEGPPGETEPVT 16883
Score = 118 bits (294), Expect = 2e-25, Method: Composition-based stats.
Identities = 85/581 (15%), Positives = 160/581 (28%), Gaps = 75/581 (13%)
Query 68 KTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLT-CNILTFGQLEQNVYGI-------- 118
+ ++ + K + T + + + LT F + +N YG+
Sbjct 22687 RITNYIVEKREATRKSYSTVTTKCHKCTYKVTGLTEGCEYFFRVMAENEYGVGEPTETTE 22746
Query 119 TIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKR 176
+ + P P +L+ + + W R T + ++++ +
Sbjct 22747 PVRASEAPLPPDSLNIMDITKNTVSLAWPKPRHDGGSKITGYVIEAQRKGSDQWTHISTV 22806
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH---------- 226
+ + V A N+ G+ ++ + + K + P
Sbjct 22807 KGLECVVRNLTEG--EEYTFQVMAVNSAGR-SAPRESRPVIVKEQTMLPELDLRGIYQKL 22863
Query 227 -------NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
N+ V +TW ILK + ++ +T + + +
Sbjct 22864 VIARAGDNIKVEIPVLGRPKPTVTWKKGDQ----ILKQTQRVNVENTATSTILNINECVR 22919
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
+ P T G E IT + P
Sbjct 22920 SD-----SGPYPLT-------AKNTVG--------EVGDVITIQVHDIPGPPTGPIK--F 22957
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ-----NYTVNATKLTVNLTND 394
V W+ P + I +Y V + + S K T T
Sbjct 22958 DEVSSDFVTFSWEP-PENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGV 23016
Query 395 RYLATLTVRN--LVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVK 451
Y + +N VG + + F+ P + + + + W P
Sbjct 23017 EYQFRVRAQNRYGVGPGITSASVVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGG 23076
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYL--RGNLAESKCYLITVTPVYADGPGSPES 509
IL + + K WQ + + L + Y V G P
Sbjct 23077 SPILGYHI-ERKERNGILWQTVSKALVPGNIFKSTGLTDGIAYEFRVIAENMAGKSKPSK 23135
Query 510 IKAYLKQAPPSKGPTVRTK-KVGKNEAVLEWDQLPVDVQNGF-IRNYTIFYRTII-GNET 566
+ P P + ++ L+W + GF I +Y + R + G
Sbjct 23136 PSEPMFALDPIDPPGKPVPLNITRHTVALKW--AKPEYTGGFKITSYVVEKRDLPNGRWL 23193
Query 567 AVNV-DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
N + E+T+S LT D Y R+ A G P
Sbjct 23194 KANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSE 23234
Score = 115 bits (288), Expect = 1e-24, Method: Composition-based stats.
Identities = 94/574 (16%), Positives = 164/574 (29%), Gaps = 65/574 (11%)
Query 67 WKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLP- 125
W I K + T + + + + +L ++ VY + G P
Sbjct 31959 WTKEGQDISKRAMIATSETHTELVIKEADRNDSGTYDLVLENKCGKKTVYIKVKVIGSPN 32018
Query 126 -PEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSC 182
PE P L + + +R W + + L+ R TS
Sbjct 32019 TPEGP--LEYDDIQARSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSL 32076
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS----EELSS 238
V V V AEN G S + + K N + S
Sbjct 32077 VVKGLKE-NVEYHFRVSAENQFGI--SKPLKSEEPVIPKTPLNPPEPPSNPPEVLDVTKS 32133
Query 239 ILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ L+W+ P + Y I+ + W + T T + +TV L P EY F
Sbjct 32134 SVSLSWSRPKDDGGSRVTGYYIERKETSTDKW--VRHNKTQITTTMYTVTGLVPDAEYQF 32191
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
RI + G S SE D+PS+ + +V L W+ P
Sbjct 32192 RIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEIL-----SISKDSVTLQWEK-PEC 32245
Query 358 EANGKILDYEVTLTRW------KSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA 411
+ +IL Y V + KS+ + + L Y + N G S
Sbjct 32246 DGGKEILGYWVEYRQSGDSAWKKSNKERIKDRQFTIGGLLEATEYEFRVFAENETGLSRP 32305
Query 412 --AVLTIPACDFQATHPVMDLKAFPKDNML----WVEWTTPRESVKKYILEWCVLSDKAP 465
+++ P + + L + + ++W +
Sbjct 32306 RRTAMSVKTKLTSGEAPGVRKEMADVTTKLGEAAQLSCQIVGRPLPD--IKWYRFGKELI 32363
Query 466 CITDWQQEDGTVHRTYLR--GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
++ T + Y T G ES L QA P P
Sbjct 32364 QSRKYKMSSDGRTHTLTVMTDEQEDEGVY--TCVATNE--VGEVESSSKLLLQAAPQFHP 32419
Query 524 --TVRTKKVGK--NEAVLEW----DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH- 574
++ K G + L +P + ++ N + ++++
Sbjct 32420 GYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTW--------FHGQKLLQNSEKITIENTEH 32471
Query 575 -TEYTLSSLTSDTL---YMVRMAAYTDEGGKDGP 604
T + ++ T Y V++ G D
Sbjct 32472 YTHLVMKNVQRKTHAGKYKVQL--SNAFGTVDAT 32503
Score = 115 bits (287), Expect = 2e-24, Method: Composition-based stats.
Identities = 76/525 (14%), Positives = 138/525 (26%), Gaps = 77/525 (15%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKS------EWATHKFADCKAKRDTPTS 181
L + + W + T++ ++ + C +RD
Sbjct 17805 IKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGKKKEAWRQCN-RRDVEEL 17863
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPP-------------HNL 228
+ E V+A N G + K + PP ++
Sbjct 17864 EFTVEDLIEGGEYEFRVKAVNEAGVSKPSATVGPVIVKDQTCPPAIELKEFMEVEEGTDV 17923
Query 229 SVINSEELSSILKLTW--TNPSIKSVI-ILKYNIQY-RTKDASTWSQIPPEDTASTRSSF 284
+++ + LTW P + Y+ + T + + P+ S +
Sbjct 17924 NIVAKIKGVPFPTLTWFKAPPKKPDSKEPVVYDTHVNKQVVDDTCTLVIPQSRRSDTGLY 17983
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGY 344
++ + G S+E RP S Q
Sbjct 17984 SIT-------------AVNNLG-----TASKEMRLNVL-GRPGPPVGPIKFESISADQ-- 18022
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK-----LTVNLTNDRYLAT 399
+ L W P + KI +Y + + K + L Y+
Sbjct 18023 --MTLSWLP-PKDDGGSKITNYVIEKREANRKTWVRVSSEPKECMYTIPKLLEGHEYVFR 18079
Query 400 LTVRNLVG------KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKY 453
+ +N G + + P + N + V W P
Sbjct 18080 IMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVS---SVTRNSMTVNWEEPEYDGGSP 18136
Query 454 ILEWCVLSDKAPCITDWQQEDG------TVHRTYLRGNLAESKCYLITVTPVYADGPGS- 506
+ + + W++ + T+ +Y L E Y V + A G G
Sbjct 18137 VTGYWLEMKDTTS-KRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPA 18195
Query 507 --PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN 564
P P P + K+ LEW P+ I Y + Y+
Sbjct 18196 SLPSDPVTARDPVAPPGPPFPKVTDWTKSSVDLEWSP-PLKDGGSKITGYIVEYKEEGKE 18254
Query 565 ETAVNVDSSH--TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
E D T+ ++ L Y R+ A G + E T
Sbjct 18255 EWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNVAGVGEPGEVT 18299
Score = 114 bits (285), Expect = 2e-24, Method: Composition-based stats.
Identities = 62/368 (17%), Positives = 112/368 (30%), Gaps = 36/368 (10%)
Query 262 RTKDASTWSQ------IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
K + W + DT + ++SF + + K + ++I + GK
Sbjct 14815 YPKAEAEWFKENEPLSTKTVDTTAEQTSFRISEAKKDDKGRYKIVLQNKHGK-------- 14866
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK- 374
I + P ++ + T V L W+ P + KI+ Y V K
Sbjct 14867 AEGFINLQVIDVPGP--VRNLEVTETFDG-EVSLAWEE-PLTDGGSKIIGYVVERRDIKR 14922
Query 375 SHLQNYTVNATKLTVNLTNDR-----YLATLTVRNLVGKSDAAVLTIPACDFQA---THP 426
T A +T + YL ++ RN VG + P P
Sbjct 14923 KTWVLVTDRADSCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDSPVEARSKYDVPGP 14982
Query 427 VMDLKAFPKDN-MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR-TYLRG 484
+++ + + + W P I + + I +
Sbjct 14983 PLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVT 15042
Query 485 NLAESKCYLITVTPVYADGPGSPESIKAYLKQA----PPSKGPTVRTKKVGKNEAVLEWD 540
++ E + Y V G G P + ++K A PS + + ++ L W+
Sbjct 15043 DVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLNASEQTQSSVQLTWE 15102
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
P+ I Y I R + Y ++ L Y+ R++A
Sbjct 15103 P-PLKDGGSPILGYIIERREEGKDNWIRCNMKPVPELTYKVTGLQKGNKYLYRVSAENAA 15161
Query 599 GGKDGPEF 606
G D E
Sbjct 15162 GVSDPSEI 15169
Score = 111 bits (276), Expect = 3e-23, Method: Composition-based stats.
Identities = 99/613 (16%), Positives = 186/613 (30%), Gaps = 89/613 (15%)
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILK 256
+ A+N+ G I + + + P P NL V N + + ++W NP I
Sbjct 19770 ISAKNSSGHAQGSAI-VNVLDR--PGPCQNLKVSNVTKEN--CTISWENPLDNGGSEITN 19824
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
+ ++YR + WS + + +L EY FR+ + G G +
Sbjct 19825 FIVEYRKPNQKGWSIV----ASDVTKRLVKANLLANNEYYFRVCAENKVGVGPTIETKTP 19880
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
I DRP + + +G V L W+ P ++ L Y V S
Sbjct 19881 ILAINPIDRPGEPENLHI-----ADKGKTFVYLKWR-RPDYDGGSPNLSYHVERRLKGSA 19934
Query 377 LQNYTVNATKLTVN------LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
+ + + N Y + +N G+SD PV+DL
Sbjct 19935 DWERVHKGSIKETHYMVDKCVENQIYEFRVQTKNEGGESDWVRTEEVVVKEDLQKPVLDL 19994
Query 431 KAFP-----KDNML------------WVEWTTPRESVKKYILEWCVLSDKAPCITDWQQE 473
K + + V WT +++ L+ D E
Sbjct 19995 KLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDAT--------DLTRSPRVKIDTSAE 20046
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN 533
+ + ++ Y+IT G + L + P ++ V +
Sbjct 20047 SSKF--SLTKAKRSDGGKYVIT--ATNPAGSFVAYATVNVLDK--PGPVRNLKITDVSSD 20100
Query 534 EAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+ WD P D I+NY + + + + + T++ L Y+ R+
Sbjct 20101 RCTIRWDP-PEDDGGCEIQNYILEKCESKRMVWSTYSANVLTPSATVTRLIEGNEYIFRV 20159
Query 593 AAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDL-----I 647
A G E P A+ + + P + + +N + I
Sbjct 20160 RAENKIGTGPPTESK---PVIAKTKYDRPGRPDPPEVTKVSKEEMTVVWNAPEYDGGKSI 20216
Query 648 KKHIWPNVPDPSKSHIAQWSP---HTPPRHNFNSKDQMY----------------SDGNF 688
+ + H +W P P ++ + + +
Sbjct 20217 TGYYLEK----KEKHAVRWVPVNKSAIPERRLKVQNLLPGHEYQFRVKAENEVGIGEPSL 20272
Query 689 TDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCM---SSSRPSISSSD 745
VV + + P + K +D K G GG+ + RP I+ +
Sbjct 20273 PSRPVVAKDPIEPPGPPTNFKVVDTTKSSITLAWGKPVYDGGAPIIGYVVEMRPKIADAS 20332
Query 746 ENESSQNTSSTVQ 758
+E + ++ Q
Sbjct 20333 PDEGWKRCNAAAQ 20345
Score = 102 bits (254), Expect = 1e-20, Method: Composition-based stats.
Identities = 73/523 (14%), Positives = 142/523 (27%), Gaps = 56/523 (11%)
Query 126 PEKPKNLSCIVNEGKKMRCEWD-GGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCT 183
P +P L + + +W+ + E + ++ + K
Sbjct 32220 PSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDRQF 32279
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
+ E V AEN G K+ + +T
Sbjct 32280 TIGGLLEATEYEFRVFAENETGLSRPRRTAMSVKTKLTSG-------EAPGVRKEMADVT 32332
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
L I R W + E S + + + + +
Sbjct 32333 TKLGEAAQ---LSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDG----RTHTLTVMTDE 32385
Query 304 EDGKGYWSDW-------SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL------- 349
++ +G ++ E +S + + P P + K G T++L
Sbjct 32386 QEDEGVYTCVATNEVGEVESSSKLLLQAAPQFHPGYPLKEKYYGAVGS-TLRLHVMYIGR 32444
Query 350 -----VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRN 404
W N + ++T+ + + N V + + N
Sbjct 32445 PVPAMTWFHGQKLLQNSE----KITIENTEHYTHLVMKN-----VQRKTHAGKYKVQLSN 32495
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
G DA + + ++A N + + W P + +I + V +A
Sbjct 32496 AFGTVDATLDVEIQDKPDKPTGPIVIEAL-LKNSVVISWKPPADDGGSWITNYVVEKCEA 32554
Query 465 PCITDWQQEDGTVH-RTYLRGNLAESKCYLITVTPVYADGPGSP----ESIKAYLKQAPP 519
+WQ + T NL E+ Y V+ G P + P
Sbjct 32555 KEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISEPLEVASIVIIKSPFEKP 32614
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEY 577
V K+ V+ W P IRNY + R N+ + T +
Sbjct 32615 GVPGKPTITAVTKDSCVVAWKP-PASDGGAKIRNYYLERREKKQNKWIAVTTEEIRETVF 32673
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
++ +L Y R+ G + + P + ++
Sbjct 32674 SVQNLIEGLEYEFRVKCENLGG--ESEWSEISEPVTPKSDVPI 32714
Score = 75.7 bits (184), Expect = 2e-12, Method: Composition-based stats.
Identities = 33/129 (26%), Positives = 52/129 (40%), Gaps = 12/129 (9%)
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILK 256
V A+N G D + P+PP + V + S + LTWT P S +
Sbjct 32890 VCAKNRFGI---DQKTVELDVADVPDPPRGVKVSDVSRDS--VNLTWTEPASDGGSKVTN 32944
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y ++ A W ++ + +TV +L T Y FR+ + G S+ SE
Sbjct 32945 YIVEKCATTAERWLRVGQAR----ETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEP 33000
Query 317 ASGITYEDR 325
+T ED+
Sbjct 33001 --TVTKEDK 33007
Score = 36.8 bits (83), Expect = 1.5, Method: Composition-based stats.
Identities = 84/539 (16%), Positives = 152/539 (28%), Gaps = 93/539 (17%)
Query 19 ESTGELLDPCGYISPESPV-VQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTI--- 74
E+ +L+P +I P V + T C I W H +
Sbjct 7899 EALVSVLEPPYFIEPLEHVEAAIGEPITLQC-------KVDGTPEIRISWYKEHTKLRSA 7951
Query 75 PKEQYTIINRTASSVTFTDIASLNIQLTCNILTF-GQLEQNVYGITIISGLPPEK----- 128
P + N AS V S + TC G + + + LPP
Sbjct 7952 PAYKMQFKNNVASLVINKVDHSDVGEYTCKAENSVGAVASSAVLVIKERKLPPSFARKLK 8011
Query 129 --------PKNLSCIVNEGKKMRCEW----DGGRET-HLETNFTLKSEWATHKFADCKAK 175
P C +N + ++ W + ++ +L+ +F AT +
Sbjct 8012 DVHETLGFPVAFECRINGSEPLQVSWYKDGELLKDDANLQMSFVHHV--ATLQILQTDQS 8069
Query 176 RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP---NPPHNLSVIN 232
+C+ A N LG +S ++V P P ++ +
Sbjct 8070 HVGQYNCS----------------ASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLAL 8113
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS-TRSSFTVQDLKP 291
E S +T T P + I+ + E+TA+ T D
Sbjct 8114 GESGSFKCHVTGTAPIKITWAKDNREIR----PGGNYKMTLVENTATLTVLKVAKGDAGQ 8169
Query 292 FTEYVFRIRCMKEDGKGYWSD---WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
+T Y GK S E I D+ Y G ++
Sbjct 8170 YTCY-----ASNVAGKDSCSAQLGVQEPPRFIKKLDQSRIVKQDEYTRYECKIGGSPEIK 8224
Query 349 LVWKTLPPFEANGKILDYE--VTLTRWKSHLQNYTVNATKLTVNLT--NDRYLATLTVRN 404
++W Y+ V + ++ + L ++ D T RN
Sbjct 8225 VLW--------------YKDEVEIQESSKFRMSFEDSVAILEMHSLSVEDSGDYTCEARN 8270
Query 405 LVGKSDAAV---LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
G + ++ + P + PV LK ++ T P + + W
Sbjct 8271 AAGSASSSTSLKVKEPPVFRKKPFPVETLKGADVHLECELQGTPP------FQVSWHKDK 8324
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS 520
+ ++ + + N+ + GS + + +APP
Sbjct 8325 RELRSGKKYKIMSENLLTSIHILNVDTADIGEYQCKATND--VGSDTCVGSVTMKAPPQ 8381
>sp|P0C5E4|PTPRQ_MOUSE Phosphatidylinositol phosphatase PTPRQ
OS=Mus musculus OX=10090 GN=Ptprq PE=1 SV=1
Length=2300
Score = 240 bits (613), Expect = 2e-64, Method: Composition-based stats.
Identities = 120/613 (20%), Positives = 217/613 (35%), Gaps = 47/613 (8%)
Query 58 FHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS---LNIQLTC-NILTFGQLEQ 113
+ N I+ + K IN T S+ +D+ + +T G+
Sbjct 877 PPLEPNGIILYYTVYVWDKVSLKTINATEVSLELSDLDYHADYSAYVTASTRFGDGKTRS 936
Query 114 NVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGG-RETHLETNFTLKSEWATHKFA-- 170
+V G P + PK++ + + W + + +++ + + F
Sbjct 937 SVINFRTPEGEPSDPPKDVHYVNLSSSSIILFWTPPVKPNGIIQYYSVYYQNTSSTFVQN 996
Query 171 ----DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV--TSDHINFDPVYKVKPNP 224
+ + T Y F W+ A +G +SD I+ Y + P
Sbjct 997 FTLLEVTQEPGNVTVSARIYKLAVFSYYTFWLTASTLVGNGNKSSDVIHV---YTDQDIP 1053
Query 225 PHNLSVINSEELSSI-LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
+ + E LSS + ++WT PS + ++ Y + + + + PP T +S
Sbjct 1054 EGGVGNLTYESLSSTAINVSWTPPSQPNGLVFYY-VSLNLQQSPPRHRRPPLTTY--ENS 1110
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+L+ +T+Y+F+I E KG+ ++ + T ED P P I+
Sbjct 1111 IYFDNLEKYTDYIFKITPSTE--KGFSETYTAQLHIKTEEDVPDTPP----IINTFKNLS 1164
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV-NATKLTVNLTNDRYLATLTV 402
++ L W PP + NG IL Y +TL ++ T N L Y
Sbjct 1165 STSILLSWD--PPLKPNGAILSYHLTLQGTHANRTFVTSGNHIVLEELSPFTLYSFLAAA 1222
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLS 461
R + G +++L + P +L + +W+ W+ + +
Sbjct 1223 RTMKGLGPSSILFFYTDESAPLAPPQNLTLINYTSDFVWLTWSPSPLPGGIVKVYSFKIH 1282
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES--IKAYLKQAPP 519
+ ++ G L G L Y I+V+ G G+ S +K +++ P
Sbjct 1283 EHETDTVFYKNISGFQTDAKLAG-LEPVSTYSISVSAFTKVGNGNQFSNVVKFTTQESVP 1341
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTL 579
+ + WD P NG I +Y I T+ GN T V+ YT
Sbjct 1342 DAVQNIACVARDWQSVSVMWD--PPRKANGIIIHYMI---TVEGNSTKVSPRDP--MYTF 1394
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT-PKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
+ L ++T Y+ + A T G + + +T P+ VP AF V
Sbjct 1395 TKLLANTSYIFEVRASTSAGEGNESQCNVSTLPET------VPSVPTNTAFSNVQSTSVT 1448
Query 639 FCFNKRDLIKKHI 651
+ K D I +
Sbjct 1449 LRWIKPDTILGYF 1461
Score = 193 bits (489), Expect = 7e-49, Method: Composition-based stats.
Identities = 96/530 (18%), Positives = 184/530 (35%), Gaps = 48/530 (9%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGG-RETHLETNFTLKS 162
++ E+N + P P+++ ++ W + + + +
Sbjct 644 HVGESSLSEENDLFVRTPEDEPESSPQDVKVTDVSPSELSLTWSPPEKPNGIIIAYEVFY 703
Query 163 EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL--GKVTSDHINFDPVYKV 220
+ A F + + S + + +++ L G +S ++ V
Sbjct 704 QNADALFVKNTSTTNITLS-----DLKPYTLYNISIQSYTRLGHGNQSSSLLSVRTSETV 758
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
+ P N++ N S +++ + P + II KY I + ++ I T
Sbjct 759 PDSAPENITYKNI--SSEEIEIFFLPPRSPNGIIQKYTIYLKRSNSHEARTIET-----T 811
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
+ T+ LK +T YV + G+G S S +T ED P P + S
Sbjct 812 SLTLTIGGLKKYTHYVIEVSASTLKGEGV---RSMPISILTEEDAPDSPPQNFSVKQLSG 868
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL 400
TV L W+ PP E NG IL Y V + + T+NAT++++ L++ Y A
Sbjct 869 V----TVMLSWQ--PPLEPNGIILYYTVYVW---DKVSLKTINATEVSLELSDLDYHADY 919
Query 401 TVRNLV------GKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKY 453
+ GK+ ++V+ + + + P D+ + + + WT P +
Sbjct 920 SAYVTASTRFGDGKTRSSVINFRTPEGEPSDPPKDVHYVNLSSSSIILFWTPPVKP-NGI 978
Query 454 ILEWCVLSDKAPC-------ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
I + V + + QE G V + LA Y +T G G+
Sbjct 979 IQYYSVYYQNTSSTFVQNFTLLEVTQEPGNVTVSARIYKLAVFSYYTFWLTASTLVGNGN 1038
Query 507 PES--IKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY-TIFYRTII 562
S I Y Q P G + + + + W P NG + Y ++ +
Sbjct 1039 KSSDVIHVYTDQDIPEGGVGNLTYESLSSTAINVSW--TPPSQPNGLVFYYVSLNLQQSP 1096
Query 563 GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
+ + +L T Y+ ++ T++G +
Sbjct 1097 PRHRRPPLTTYENSIYFDNLEKYTDYIFKITPSTEKGFSETYTAQLHIKT 1146
Score = 190 bits (482), Expect = 5e-48, Method: Composition-based stats.
Identities = 91/518 (18%), Positives = 163/518 (31%), Gaps = 43/518 (8%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRET-HLETNFTLKSEWATHKFADCKAKR 176
I P P+N S G + W E + +T+ + K
Sbjct 847 ILTEEDAPDSPPQNFSVKQLSGVTVMLSWQPPLEPNGIILYYTVYV------WDKVSLKT 900
Query 177 DTPTSCTVDYSTV-YFVNIEVWVEAENALG--KVTSDHINFDPVYKVKPNPPHNLSVINS 233
T +++ S + Y + +V A G K S INF +PP + V
Sbjct 901 INATEVSLELSDLDYHADYSAYVTASTRFGDGKTRSSVINFRTPEGEPSDPPKD--VHYV 958
Query 234 EELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA----STRSSFTVQDL 289
SS + L WT P + II Y++ Y+ ++ + + S + L
Sbjct 959 NLSSSSIILFWTPPVKPNGIIQYYSVYYQNTSSTFVQNFTLLEVTQEPGNVTVSARIYKL 1018
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
F+ Y F + G G S S+ T +D P S T + +
Sbjct 1019 AVFSYYTFWLTASTLVGNGNKS--SDVIHVYTDQDIPEGGVGNLTYESLSST----AINV 1072
Query 350 VWKTLPPFEANGKILDY---EVTLTRWKSHLQNYTVNATKLTVNLTN--DRYLATLTVRN 404
W PP + NG + Y + + + T + + Y+ +T
Sbjct 1073 SW--TPPSQPNGLVFYYVSLNLQQSPPRHRRPPLTTYENSIYFDNLEKYTDYIFKITPST 1130
Query 405 LVGKSDAAVLTI---PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
G S+ + D T P+++ + + W P + IL + +
Sbjct 1131 EKGFSETYTAQLHIKTEEDVPDTPPIINTFKNLSSTSILLSWDPPLKP-NGAILSYHLTL 1189
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
T + T + L+ Y G G + Y ++ P
Sbjct 1190 QG----THANRTFVTSGNHIVLEELSPFTLYSFLAAARTMKGLGPSSILFFYTDESAPLA 1245
Query 522 GP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTL 579
P + + L W P+ G ++ Y+ + N+ T+ L
Sbjct 1246 PPQNLTLINYTSDFVWLTWSPSPL--PGGIVKVYSFKIHEHETDTVFYKNISGFQTDAKL 1303
Query 580 SSLTSDTLYMVRMAAYTDEGGKD--GPEFTFTTPKFAQ 615
+ L + Y + ++A+T G + FTT +
Sbjct 1304 AGLEPVSTYSISVSAFTKVGNGNQFSNVVKFTTQESVP 1341
Score = 181 bits (459), Expect = 3e-45, Method: Composition-based stats.
Identities = 85/435 (20%), Positives = 148/435 (34%), Gaps = 31/435 (7%)
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN-SEELSSILKLTWTNPSI 249
F + V A +G+ + +V P ++ +IN SS + L W P
Sbjct 539 FTEHTISVSAFTVMGEGPPTVLTVRTREQV----PSSIQIINYKNISSSSILLYWDPPEY 594
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ I Y I D + Q+ D +SF + LK +T Y R+ G+
Sbjct 595 PNGKITHYTIYAMELDTNRAFQMTTVD-----NSFLITGLKKYTRYKMRVAASTHVGESS 649
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
S+ + T ED P +P D S + L W PP + NG I+ YEV
Sbjct 650 LSE-ENDLFVRTPEDEPESSPQDVKVTDVS----PSELSLTWS--PPEKPNGIIIAYEVF 702
Query 370 LTRWKSHLQNYTVNATKLTVNL-TNDRYLATLTVRNLVGKS--DAAVLTIPACDFQATHP 426
+ T +L Y ++ +G +++L++ +
Sbjct 703 YQNADALFVKNTSTTNITLSDLKPYTLYNISIQSYTRLGHGNQSSSLLSVRTSETVPDSA 762
Query 427 VMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
++ + + P S I ++ + + + T T G L
Sbjct 763 PENITYKNISSEEIEIFFLPPRSPNGIIQKYTIYL--KRSNSHEARTIETTSLTLTIGGL 820
Query 487 AESKCYLITVTPVYADGPGSPE-SIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPV 544
+ Y+I V+ G G I ++ P P K++ +L W P
Sbjct 821 KKYTHYVIEVSASTLKGEGVRSMPISILTEEDAPDSPPQNFSVKQLSGVTVMLSWQ--PP 878
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD--EGGKD 602
NG I YT++ + +T ++++ LS L Y + A T +G
Sbjct 879 LEPNGIILYYTVYVWDKVSLKT---INATEVSLELSDLDYHADYSAYVTASTRFGDGKTR 935
Query 603 GPEFTFTTPKFAQGE 617
F TP+ +
Sbjct 936 SSVINFRTPEGEPSD 950
Score = 177 bits (449), Expect = 4e-44, Method: Composition-based stats.
Identities = 113/711 (16%), Positives = 218/711 (31%), Gaps = 99/711 (14%)
Query 53 KCMDYFHVNANYIVWK---TNHFTIPKEQYTIINRT-ASSVTFTDIASLNIQLT----CN 104
N +V+ N P T +S+ F ++ +
Sbjct 1071 NVSWTPPSQPNGLVFYYVSLNLQQSPPRHRRPPLTTYENSIYFDNLEKYTDYIFKITPST 1130
Query 105 ILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH---LETNFTLK 161
F + I +P P + + WD + + L + TL+
Sbjct 1131 EKGFSETYTAQLHIKTEEDVPDTPPIINTFKNLSSTSILLSWDPPLKPNGAILSYHLTLQ 1190
Query 162 SEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK 221
A F V F A G S + F
Sbjct 1191 GTHANRTFVTSGNH-------IVLEELSPFTLYSFLAAARTMKGLGPSSILFFYTDESAP 1243
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
PP NL++IN S + LTW+ + I+ Y+ + + T + ++ + +
Sbjct 1244 LAPPQNLTLINY--TSDFVWLTWSPSPLPGGIVKVYSFKIHEHETDT---VFYKNISGFQ 1298
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+ + L+P + Y + + G G +S T E P +
Sbjct 1299 TDAKLAGLEPVSTYSISVSAFTKVGNGN--QFSNVVKFTTQESVPDA-----VQNIACVA 1351
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLT 401
+ +++V ++W PP +ANG I+ Y +T+ + + T T L N Y+ +
Sbjct 1352 RDWQSVSVMWD--PPRKANGIIIHYMITVEGNSTKVSPRDPMYT-FTKLLANTSYIFEVR 1408
Query 402 VRNLVGKSDAAVLTIPACDFQATHPVMDLK-AFPKDNMLWVEWTTPRESVKKYILEWCVL 460
G+ + + + + + + + + W P +++ Y + +
Sbjct 1409 ASTSAGEGNESQCNVSTLPETVPSVPTNTAFSNVQSTSVTLRWIKP-DTILGYFQNYKIT 1467
Query 461 SD-KAPCITDWQQED--GTVHRTYLRG---------NLAESKCYLITVTPVYADGPGSPE 508
+ +A +W+ E+ YL L + + Y V G G+
Sbjct 1468 TQLRAQKCREWEPEECVEHQEVQYLYEANQTEDTVRGLKKFQWYRFQVAASTNAGYGNAS 1527
Query 509 SIKAY-LKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRN---YTIFYRTIIG 563
S + PP P VR + W++ I Y I +++
Sbjct 1528 SWISTQTLPGPPDGPPENVRVVATSPFGINISWNEP------AIITGPTFYLIDVKSVDN 1581
Query 564 NETAVN-VDSSHTEYT--LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
+ ++ V S+ T ++ L T Y V + A+ G G + G+ A
Sbjct 1582 DNFNISFVKSNEENKTTEINDLEVFTRYSVVITAF--VGNVSGA--------YTDGKSSA 1631
Query 621 IVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVP-DPSKSHIAQWSPHTPPRHNFNSK 679
V+ L +VP DP + Q P + +
Sbjct 1632 EVIITTL-------------------------ESVPKDPPNNMTFQKIPDEVTKFQLSFL 1666
Query 680 DQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGG 730
+GN + +D P + +L + +K + G+ G
Sbjct 1667 PPSQPNGNIQVYQALVYREDD--PTAVQIHNLSIIQKTDTSVIAMLEGLKG 1715
Score = 161 bits (406), Expect = 9e-39, Method: Composition-based stats.
Identities = 80/550 (15%), Positives = 158/550 (29%), Gaps = 52/550 (9%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSE 163
++ G +V + +P NL+ + W + + + +
Sbjct 1032 TLVGNGNKSSDVIHVYTDQDIPEGGVGNLTYESLSSTAINVSWTPPSQPNGLVFYYVSLN 1091
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN--ALGKVTSDHINFDPVYKVK 221
+ T + + + + + + + ++ V
Sbjct 1092 LQQSPPRHRRPPLTTYENSIYFDNLEKYTDYIFKITPSTEKGFSETYTAQLHIKTEEDVP 1151
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
PP + N S+ + L+W P + IL Y++ + ++
Sbjct 1152 DTPPIINTFKNL--SSTSILLSWDPPLKPNGAILSYHL-------TLQGTHANRTFVTSG 1202
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+ +++L PFT Y F G G S T E P P I+ +
Sbjct 1203 NHIVLEELSPFTLYSFLAAARTMKGLG----PSSILFFYTDESAPLAPPQNLTLINYTSD 1258
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS---HLQNYTVNATKLTVNLTNDRYLA 398
V L W P K+ +++ + + KL Y
Sbjct 1259 F----VWLTWSPSPLPGGIVKVYSFKIHEHETDTVFYKNISGFQTDAKLAGLEPVSTYSI 1314
Query 399 TLTVRNLVGKS-DAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRESVKKYILE 456
+++ VG + + V ++ +D + V W PR++ I+
Sbjct 1315 SVSAFTKVGNGNQFSNVVKFTTQESVPDAVQNIACVARDWQSVSVMWDPPRKA-NGIIIH 1373
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA-YLK 515
+ + + T D Y L + Y+ V + G G+ L
Sbjct 1374 YMITVEG--NSTKVSPRDPM----YTFTKLLANTSYIFEVRASTSAGEGNESQCNVSTLP 1427
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN----------- 564
+ PS V L W + D G+ +NY I +
Sbjct 1428 ETVPSVPTNTAFSNVQSTSVTLRW--IKPDTILGYFQNYKITTQLRAQKCREWEPEECVE 1485
Query 565 --ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTT----PKFAQGE 617
E +++ TE T+ L Y ++AA T+ G + + T P
Sbjct 1486 HQEVQYLYEANQTEDTVRGLKKFQWYRFQVAASTNAGYGNASSWISTQTLPGPPDGPPEN 1545
Query 618 IEAIVVPVCL 627
+ +
Sbjct 1546 VRVVATSPFG 1555
Score = 151 bits (381), Expect = 8e-36, Method: Composition-based stats.
Identities = 93/508 (18%), Positives = 164/508 (32%), Gaps = 56/508 (11%)
Query 112 EQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFT--LKSEWATHKF 169
+ ++ ++SG PE C N + W + + T L++ ++
Sbjct 204 DVSIKVEDLLSGKLPE------CNENSDSFL---WSTTSPSPTLSRATPPLRTTHLSNTL 254
Query 170 ADCKAKRDTPTSCTVDYSTVY-FVNIEVWVEA-ENALGKVTSDHINFDPVYKVKPNPPHN 227
A K + + + + V A G + S V PP N
Sbjct 255 ARNKISSVWKEPISFVVTHLRPYTTYLFEVSAVTTEAGYIDST--IVRTPESVPEGPPQN 312
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
I ++W P+I + Y ++ D ++ F
Sbjct 313 C--ITGNVTGKAFSISWDPPAIVTGKF-SYRVELYGPTGR------ILDNSTKDLRFVFT 363
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV 347
L PFT Y + G G S+ S T D P +
Sbjct 364 HLTPFTMYDVYVAAETSAGVGPKSN----LSVFTPPDVPGAVFDLQIV-----EVEATEI 414
Query 348 QLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG 407
++ W+ P + NG I Y V ++ +S + + T LT D Y+ N
Sbjct 415 RVSWRK--PRQPNGIISQYRVKVSVLESGV---ILENTLLTGQ---DEYI------NNPM 460
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
+ L P F M + ++ P + + +E S
Sbjct 461 TPEIMNLVDPMIGFYEGSGEMSSDLHSLASFIYNS--HPHDFPARTRVED-QRSPVVATR 517
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
+ + H +Y+ L + I+V+ G G P + ++ PS +
Sbjct 518 NQYMTDIAAEHLSYVIRRLVPFTEHTISVSAFTVMGEGPPTVLTVRTREQVPSSIQIINY 577
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTL 587
K + + +L WD P + NG I +YTI+ + N A + + + ++ L T
Sbjct 578 KNISSSSILLYWD--PPEYPNGKITHYTIYAMELDTN-RAFQMTTVDNSFLITGLKKYTR 634
Query 588 YMVRMAAYTDEGGKDGPEFT---FTTPK 612
Y +R+AA T G E TP+
Sbjct 635 YKMRVAASTHVGESSLSEENDLFVRTPE 662
Score = 149 bits (375), Expect = 4e-35, Method: Composition-based stats.
Identities = 90/568 (16%), Positives = 173/568 (30%), Gaps = 79/568 (14%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSC 182
P P+NL+ I + W L + K + + +
Sbjct 1241 SAPLAPPQNLTLINYTSDFVWLTWSPSP---LPGGIVKVYSF---KIHEHETDTVFYKNI 1294
Query 183 TVDYSTVYF------VNIEVWVEAENALGKVT--SDHINFDPVYKVKPNPPHNLSVINSE 234
+ + + V A +G S+ + F V P+ N++ + +
Sbjct 1295 SGFQTDAKLAGLEPVSTYSISVSAFTKVGNGNQFSNVVKFTTQESV-PDAVQNIACVARD 1353
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
S + + W P + II+ Y I +++ P D +T L T
Sbjct 1354 WQS--VSVMWDPPRKANGIIIHYMITVEGNS----TKVSPRD-----PMYTFTKLLANTS 1402
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y+F +R G+G S + + T P PS S+ Q +V L W +
Sbjct 1403 YIFEVRASTSAGEGNES----QCNVSTL---PETVPSVPTNTAFSNVQST-SVTLRW--I 1452
Query 355 PPFEANGKILDYEVT-------LTRW-------KSHLQN-YTVNATKLTVNLTNDRYLAT 399
P G +Y++T W +Q Y N T+ TV
Sbjct 1453 KPDTILGYFQNYKITTQLRAQKCREWEPEECVEHQEVQYLYEANQTEDTVRGLKKFQWYR 1512
Query 400 LTV---RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN-MLWVEWTTPRESVKK--Y 453
V N + ++ ++ P +++ + + W P Y
Sbjct 1513 FQVAASTNAGYGNASSWISTQTLPGPPDGPPENVRVVATSPFGINISWNEPAIITGPTFY 1572
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG------SP 507
+++ + + I+ + + +L Y + +T + G S
Sbjct 1573 LIDVKSVDNDNFNISFVKSNEENKTTEI--NDLEVFTRYSVVITAFVGNVSGAYTDGKSS 1630
Query 508 ESIKAYLKQAPPSKGPTVRTKKVGKNEAV-LEWDQLPVDVQNGFIRNY-TIFYRTIIGNE 565
+ ++ P P T + +E + LP NG I+ Y + YR
Sbjct 1631 AEVIITTLESVPKDPPNNMTFQKIPDEVTKFQLSFLPPSQPNGNIQVYQALVYREDDPTA 1690
Query 566 TAVN----VDSSHTEYT--LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE 619
++ + + T L L Y + + A G + T A +
Sbjct 1691 VQIHNLSIIQKTDTSVIAMLEGLKGGHTYNISVYAINSAGAGPKVQMRITMDIKAPARPK 1750
Query 620 AIVVPV---CLAFLLTTLLGVLF---CF 641
+P+ L+T+ + C+
Sbjct 1751 TKPIPIHDATGKLLVTSTTITIRMPICY 1778
Score = 132 bits (331), Expect = 7e-30, Method: Composition-based stats.
Identities = 57/410 (14%), Positives = 108/410 (26%), Gaps = 81/410 (20%)
Query 209 SDHINFDPVYKV-KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS 267
S ++ V KP PP L+ + L+W P + I+ Y ++Y+
Sbjct 43 SSPVSRTLATNVSKPGPPVFLAGERVGSAG--ILLSWNTPPNPNGRIISYVVKYKEVCPW 100
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
+ + +L P T Y ++ G G +SD T E P
Sbjct 101 MQTAYTRVRAKPDSLEVLLTNLNPGTTYEIKVAAENSAGIGVFSDPF---LFQTAESAPG 157
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH----------- 376
K + + Y V L+W P + NGKI +++++ +S
Sbjct 158 KVVNLTVEA-----LNYSAVNLIW--YLPRQPNGKITSFKISVKHARSGIVVKDVSIKVE 210
Query 377 -------------------LQNYTVNATKLTVNLTNDRYLATLTVRNLVG---KSDAAVL 414
+L+ RN + K + +
Sbjct 211 DLLSGKLPECNENSDSFLWSTTSPSPTLSRATPPLRTTHLSNTLARNKISSVWKEPISFV 270
Query 415 TI----------------------------PACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
P + + W P
Sbjct 271 VTHLRPYTTYLFEVSAVTTEAGYIDSTIVRTPESVPEGPPQNCITGNVTGKAFSISWDPP 330
Query 447 RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
K+ + + ++ T ++ +L Y + V + G G
Sbjct 331 AIVTGKFSYRVELYGPTGRIL-----DNSTKDLRFVFTHLTPFTMYDVYVAAETSAGVGP 385
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
++ + P ++ +V E + W NG I Y +
Sbjct 386 KSNLSVFTPPDVPGAVFDLQIVEVEATEIRVSWR--KPRQPNGIISQYRV 433
Score = 101 bits (251), Expect = 2e-20, Method: Composition-based stats.
Identities = 87/557 (16%), Positives = 149/557 (27%), Gaps = 99/557 (18%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
P P L+ + W+ GR + W + +AK D+
Sbjct 57 PGPPVFLAGERVGSAGILLSWNTPPNPNGRIISYVVKYKEVCPWMQTAYTRVRAKPDSLE 116
Query 181 SCTVDYSTVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ + E+ V AEN+ G V SD F P NL+V S
Sbjct 117 VLLTNLNPG--TTYEIKVAAENSAGIGVFSDPFLFQTAESA-PGKVVNLTVEALN--YSA 171
Query 240 LKLTWTNPSIKSVIILKYNIQYR----------------------------TKDASTWSQ 271
+ L W P + I + I + D+ WS
Sbjct 172 VNLIWYLPRQPNGKITSFKISVKHARSGIVVKDVSIKVEDLLSGKLPECNENSDSFLWST 231
Query 272 IPPEDTASTRS-------------------------SFTVQDLKPFTEYVFRIRCMKEDG 306
P T S + SF V L+P+T Y+F + + +
Sbjct 232 TSPSPTLSRATPPLRTTHLSNTLARNKISSVWKEPISFVVTHLRPYTTYLFEVSAVTTEA 291
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
S T E P P + + + + W PP GK Y
Sbjct 292 GYIDS-----TIVRTPESVPEGPPQNCITGNVTG----KAFSISWD--PPAIVTGK-FSY 339
Query 367 EVTLTRWKSHLQNYTVNATKLTV--NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
V L + + + + Y + G + L++
Sbjct 340 RVELYGPTGRILDNSTKDLRFVFTHLTPFTMYDVYVAAETSAGVGPKSNLSVFTPPDVPG 399
Query 425 HPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
+ + V W PR+ I ++ V + T Y+
Sbjct 400 AVFDLQIVEVEATEIRVSWRKPRQP-NGIISQYRVKVSVLESGVILENTLLTGQDEYINN 458
Query 485 NLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
+ L+ + +G G S + S V
Sbjct 459 PMTPEIMNLVDPMIGFYEGSGEMSSDL----HSLASFIYNSHPHDFPART--------RV 506
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
+ Q + N+ ++ + H Y + L T + + ++A+T G
Sbjct 507 EDQRSPVV--------ATRNQYMTDIAAEHLSYVIRRLVPFTEHTISVSAFTVMGEGPPT 558
Query 605 EFTFTTPKFAQGEIEAI 621
T T + I+ I
Sbjct 559 VLTVRTREQVPSSIQII 575
Score = 75.3 bits (183), Expect = 2e-12, Method: Composition-based stats.
Identities = 33/201 (16%), Positives = 58/201 (29%), Gaps = 19/201 (9%)
Query 394 DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR---ESV 450
Y TL+ + S T+ + PV + + W TP +
Sbjct 28 TVYDITLSSISATTYSSPVSRTLATNVSKPGPPVFLAGERVGSAGILLSWNTPPNPNGRI 87
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTY------LRGNLAESKCYLITVTPVYADGP 504
Y++++ + W Q T R L NL Y I V + G
Sbjct 88 ISYVVKYKE-------VCPWMQTAYTRVRAKPDSLEVLLTNLNPGTTYEIKVAAENSAGI 140
Query 505 GS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
G + ++ P K + + + + L W NG I ++ I +
Sbjct 141 GVFSDPFLFQTAESAPGKVVNLTVEALNYSAVNLIW--YLPRQPNGKITSFKISVKHARS 198
Query 564 NETAVNVDSSHTEYTLSSLTS 584
+V + L
Sbjct 199 GIVVKDVSIKVEDLLSGKLPE 219
Score = 72.2 bits (175), Expect = 2e-11, Method: Composition-based stats.
Identities = 43/263 (16%), Positives = 84/263 (32%), Gaps = 20/263 (8%)
Query 125 PPE-KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEW-ATHKFADCKAKRDTPTSC 182
PP+ P+N+ + + W+ T + + + F K +
Sbjct 1538 PPDGPPENVRVVATSPFGINISWNEPAIITGPTFYLIDVKSVDNDNFNISFVKSNEENKT 1597
Query 183 TVDYSTVYFVNIEVWVEAE--NALGK----VTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
T F V + A N G +S + + V +PP+N++ +
Sbjct 1598 TEINDLEVFTRYSVVITAFVGNVSGAYTDGKSSAEVIITTLESVPKDPPNNMTFQKIPDE 1657
Query 237 SSILKLTWTNPSIKSVIILKYN-IQYRTKDASTWSQIPPEDTASTRSSF--TVQDLKPFT 293
+ +L++ PS + I Y + YR D + T +S ++ LK
Sbjct 1658 VTKFQLSFLPPSQPNGNIQVYQALVYREDDPTAVQIHNLSIIQKTDTSVIAMLEGLKGGH 1717
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYE----DRPSKAPSFWYKIDPSHTQGYRTVQL 349
Y + + G G + IT + RP P + T+ +
Sbjct 1718 TYNISVYAINSAGAGP-----KVQMRITMDIKAPARPKTKPIPIHDATGKLLVTSTTITI 1772
Query 350 VWKTLPPFEANGKILDYEVTLTR 372
+ +G I + +V +
Sbjct 1773 RMPICYYNDDHGPIRNVQVLVAE 1795
>sp|Q9ERC8|DSCAM_MOUSE Cell adhesion molecule DSCAM OS=Mus musculus
OX=10090 GN=Dscam PE=1 SV=1
Length=2013
Score = 239 bits (609), Expect = 7e-64, Method: Composition-based stats.
Identities = 99/515 (19%), Positives = 179/515 (35%), Gaps = 72/515 (14%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLET----NFTLKSEWATHK------FADCKAKRDTP 179
K +SC + K + W+ +E + + + ++ + +
Sbjct 805 KEMSCTAHGEKPIIVRWE--KEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGF 862
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
SC A N+ G+ D + P+PP + + +
Sbjct 863 FSCH----------------AINSYGE---DRGIIQLTVQEPPDPPE---IEIKDVKART 900
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L WT + I Y+I+ + K S S +D + +S T+ D+ P + Y R+
Sbjct 901 ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRM 960
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
GK S+ S E + E P P ++P+ +Q ++++ WK
Sbjct 961 YAKNRIGK---SEPSNEITITADEAAPDGPPQ-EVHLEPTSSQ---SIRVTWKAPKKHLQ 1013
Query 360 NGKILDYEVTLTRWKSHLQ--------NYTVNATKLTVNLTN--DRYLATLTVRNLVGKS 409
NG I Y++ + + + T ++ T++ N +Y + N G
Sbjct 1014 NGIIRGYQIGYREYSTGGNFQFNIISIDTTGDSEVYTLDNLNKFTQYGLVVQACNRAGTG 1073
Query 410 DAA--VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI------LEWCVLS 461
++ ++T D + P + + W+T + I + W L
Sbjct 1074 PSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLI 1133
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPS 520
D + + + T + L + Y I V G G E I K+ P
Sbjct 1134 DGE--LGEIKNVT-TTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPG 1190
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF----YRTIIGNETAVNVDSSHTE 576
V+ + + W LP NG IR YT+F Y T+I E + DS
Sbjct 1191 PPAGVKAAAASASMVFVSW--LPPLKLNGIIRKYTVFCSHPYPTVIS-EFEASPDS--FS 1245
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP 611
Y + +L+ + Y V + A T G + E P
Sbjct 1246 YRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEP 1280
Score = 166 bits (419), Expect = 2e-40, Method: Composition-based stats.
Identities = 85/544 (16%), Positives = 171/544 (31%), Gaps = 42/544 (8%)
Query 84 RTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
+A+ + ++ +I++ N IT P P+ + + +R
Sbjct 943 NSATIIDIHPSSTYSIRMYAKNRIGKSEPSNEITITADEAAPDGPPQEVHLEPTSSQSIR 1002
Query 144 CEWDGGRET-------HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV 196
W ++ + + S +F + + F +
Sbjct 1003 VTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISIDTTGDSEVYTLDNLNKFTQYGL 1062
Query 197 WVEAENALGKVTSDH-INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK--SVI 253
V+A N G S I + V PP N+ I + + ++W+ S + + I
Sbjct 1063 VVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIAT--SPESISISWSTLSKEALNGI 1120
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ + + Y + ++ +T+ S + L+ +T Y ++ G G
Sbjct 1121 LQGFRVIY-WANLIDGELGEIKNVTTTQPSLELDGLEKYTNYSIQVLAFTRAGDGV---R 1176
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT-R 372
SE+ T ED P + V + W LPP + NG I Y V +
Sbjct 1177 SEQIFTRTKEDVPGPPAGVKAAAASASM-----VFVSW--LPPLKLNGIIRKYTVFCSHP 1229
Query 373 WKSHLQNYTVNATKLTVNLTN----DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+ + + + + + + N +Y + G+ +++ + +A ++
Sbjct 1230 YPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPARIL 1289
Query 429 DLKAFPKD---NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW--QQEDGTVHRTYLR 483
+ + + ++W S+ P + ++ + +R
Sbjct 1290 TFSGTVTTPWMKDIVLPCKAVGDPSPA--VKWMKDSNGTPSLVTIDGRRSIFSNGSFIIR 1347
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLP 543
AE Y A+ + I L+ P P + K + L W LP
Sbjct 1348 TVKAEDSGY----YSCVANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSITLSW--LP 1401
Query 544 VDVQNGFIRNYTIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
D IR Y + Y + + S Y L +L T Y + A G
Sbjct 1402 GDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGR 1461
Query 603 GPEF 606
E
Sbjct 1462 ISEI 1465
Score = 145 bits (366), Expect = 5e-34, Method: Composition-based stats.
Identities = 96/552 (17%), Positives = 174/552 (32%), Gaps = 59/552 (11%)
Query 99 IQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLET-- 156
+ CN G Q + T+ +P P+N+ I + + W + L
Sbjct 1063 VVQACNRAGTGPSSQEIITTTLE-DVPSYPPENVQAIATSPESISISWSTLSKEALNGIL 1121
Query 157 ---NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN 213
+ + + K T S +D + N + V A G
Sbjct 1122 QGFRVIYWANLIDGELGEIKNVTTTQPSLELDGLE-KYTNYSIQVLAFTRAGDGVRSEQI 1180
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
F + P PP V + +S++ ++W P + II KY + + I
Sbjct 1181 FTRTKEDVPGPPA--GVKAAAASASMVFVSWLPPLKLNGIIRKYTVFC---SHPYPTVIS 1235
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS------ 327
+ + S+ + +L +Y + + G+G + SE + P+
Sbjct 1236 EFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRG---NSSEIITVEPLAKAPARILTFS 1292
Query 328 ---KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA 384
P + P G + + W ++NG + R ++ +
Sbjct 1293 GTVTTPWMKDIVLPCKAVGDPSPAVKWM----KDSNGTPSLVTIDGRRSIFSNGSFIIRT 1348
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
K D + N G SD +L + P + + + + + W
Sbjct 1349 VKA-----EDSGYYSCVANNNWG-SDEIILNLQV-QVPPDQPRLTVSKT-TSSSITLSWL 1400
Query 445 TPRE---SVKKYILEWCVLSDKAPCITDWQQEDGT-VHRTYLRGNLAESKCYLITVTPVY 500
S++ YIL++ + + W + R+Y NL Y T+T
Sbjct 1401 PGDNGGSSIRGYILQYSEDNSE-----QWGSFPISPSERSYRLENLKCGTWYKFTLTAQN 1455
Query 501 ADGPGS-PESIKAYL--KQAPPSKGPTVRTKKVGKNEAVLE---WDQLPVDVQNGFIRNY 554
GPG E I+A K+ SK + + L W+ I ++
Sbjct 1456 GVGPGRISEIIEAKTLGKEPQFSKEQELFA-SINTTRVRLNLIGWND-----GGCPITSF 1509
Query 555 TIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKF 613
T+ YR T S Y L L T Y ++M G + + F T +
Sbjct 1510 TLEYRPFGTTVWTTAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCAE-KQANFATLNY 1568
Query 614 AQGEIEAIVVPV 625
I ++ V
Sbjct 1569 DGSTIPPLIKSV 1580
Score = 79.1 bits (193), Expect = 1e-13, Method: Composition-based stats.
Identities = 45/245 (18%), Positives = 81/245 (33%), Gaps = 23/245 (9%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A N G SD I + +V P+ P L+V + SS + L+W I Y +
Sbjct 1361 ANNNWG---SDEIILNLQVQVPPDQPR-LTVSKT--TSSSITLSWLPGDNGGSSIRGYIL 1414
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
QY ++ W P + + S+ +++LK T Y F + G G SE
Sbjct 1415 QYSEDNSEQWGSFP---ISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRI---SEIIEA 1468
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN 379
T P + + T+ + + W + I + + + + +
Sbjct 1469 KTLGKEPQFSKEQELFASINTTRVRLNL-IGW-----NDGGCPITSFTLEYRPFGTTVWT 1522
Query 380 YTVNATKLTVNLTNDRYLAT-----LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP 434
+ + D AT + V N G ++ +T P +
Sbjct 1523 TAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLIKSVVQ 1582
Query 435 KDNML 439
+ L
Sbjct 1583 SEEGL 1587
Score = 64.5 bits (155), Expect = 4e-09, Method: Composition-based stats.
Identities = 98/627 (16%), Positives = 184/627 (29%), Gaps = 101/627 (16%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASS----V 89
VV + VC +K + W + I K I++ +S V
Sbjct 414 SEKVVSPAEPVSLVCNVK-------GTPLPTVTWTLDDDPILKGSGHRISQMITSEGNVV 466
Query 90 TFTDIASLNIQLTCNILTFGQLEQNV--YGITIISGLPPE-KP-KNLSCIVNEGKKMRCE 145
++ +I+S ++ V Y I P +P KN++ I + C
Sbjct 467 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHC- 525
Query 146 WDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV----NIEVWVEAE 201
R +++K + + + T+ S V V +
Sbjct 526 ----RVIGYPY-YSIKWYKNANLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQ 580
Query 202 NALGKVTSDHINFDPVYKVKPN--PPHNLS-------VINSEELSSILKLTWTNPSIKSV 252
L S H+ ++P P ++ V+ S +L + +TW
Sbjct 581 PQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLP--ITITWQKDGRPIP 638
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP--FTEYVFRIRCMKEDGKGYW 310
L I D SS + +L Y C+ +
Sbjct 639 ASLGVTI----------------DNIDFTSSLRISNLSLMHNGNYT----CIARNEAAAV 678
Query 311 SDWSEEASGITY----EDRPSKAPSFWYKIDPSHTQGYRTVQLVWK-----TLPPFEA-- 359
S+ + + R I +GY +VWK +P F+
Sbjct 679 EHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIA 738
Query 360 -NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL-TVRNLVGK--SDAAVLT 415
NG+I N + L ++ + L V N VG S + LT
Sbjct 739 LNGRIQ---------------VLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 783
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
+ ++P L + + + + ++ E +++ + +E G
Sbjct 784 VKIPAMITSYPNTTLATQGQRKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVG 843
Query 476 T--VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN 533
+ + + E + + + + G I+ +++ P P + K V
Sbjct 844 EEVISTLQILPTVREDSGF-FSCHAINSYGE-DRGIIQLTVQE--PPDPPEIEIKDVKAR 899
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN----VDSSHTEYTLSSLTSDTLYM 589
L W N I Y I + + + V T+ + + Y
Sbjct 900 TITLRWTMG--FDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYS 957
Query 590 VRMAAYTDEG-GKDGPEFTFTTPKFAQ 615
+RM A G + E T T + A
Sbjct 958 IRMYAKNRIGKSEPSNEITITADEAAP 984
Score = 39.1 bits (89), Expect = 0.30, Method: Composition-based stats.
Identities = 22/152 (14%), Positives = 44/152 (29%), Gaps = 21/152 (14%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTI-PKEQYTIINRTASSV 89
ISP + S + C + + W N + P + I +++
Sbjct 318 ISPRKVKSSVGSQVSLSCSVTGN-------EDQELSWYRNGEILNPGKNVRITGLNHANL 370
Query 90 TFTDIASLNIQ-LTCNILTFGQLEQNVYGITIISGLP------------PEKPKNLSCIV 136
+ + C + Q+ + + G P P +P +L C V
Sbjct 371 IMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLVCNV 430
Query 137 NEGKKMRCEWDGGRETHLETNFTLKSEWATHK 168
W + L+ + S+ T +
Sbjct 431 KGTPLPTVTWTLDDDPILKGSGHRISQMITSE 462
>sp|Q8VHZ8|DSCAM_RAT Cell adhesion molecule DSCAM OS=Rattus norvegicus
OX=10116 GN=Dscam PE=1 SV=1
Length=2013
Score = 239 bits (609), Expect = 7e-64, Method: Composition-based stats.
Identities = 99/515 (19%), Positives = 179/515 (35%), Gaps = 72/515 (14%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLET----NFTLKSEWATHK------FADCKAKRDTP 179
K +SC + K + W+ +E + + + ++ + +
Sbjct 805 KEMSCTAHGEKPIIVRWE--KEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGF 862
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
SC A N+ G+ D + P+PP + + +
Sbjct 863 FSCH----------------AINSYGE---DRGIIQLTVQEPPDPPE---IEIKDVKART 900
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L WT + I Y+I+ + K S S +D + +S T+ D+ P + Y R+
Sbjct 901 ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRM 960
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
GK S+ S E + E P P ++P+ +Q ++++ WK
Sbjct 961 YAKNRIGK---SEPSNEITITADEAAPDGPPQ-EVHLEPTSSQ---SIRVTWKAPKKHLQ 1013
Query 360 NGKILDYEVTLTRWKSHLQ--------NYTVNATKLTVNLTN--DRYLATLTVRNLVGKS 409
NG I Y++ + + + T ++ T++ N +Y + N G
Sbjct 1014 NGIIRGYQIGYREYSTGGNFQFNIISIDTTGDSEVYTLDNLNKFTQYGLVVQACNRAGTG 1073
Query 410 DAA--VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI------LEWCVLS 461
++ ++T D + P + + W+T + I + W L
Sbjct 1074 PSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLI 1133
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPS 520
D + + + T + L + Y I V G G E I K+ P
Sbjct 1134 DGE--LGEIKNVT-TTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPG 1190
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF----YRTIIGNETAVNVDSSHTE 576
V+ + + W LP NG IR YT+F Y T+I E + DS
Sbjct 1191 PPAGVKAAAASASMVFVSW--LPPLKLNGIIRKYTVFCSHPYPTVIS-EFEASPDS--FS 1245
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP 611
Y + +L+ + Y V + A T G + E P
Sbjct 1246 YRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEP 1280
Score = 166 bits (419), Expect = 2e-40, Method: Composition-based stats.
Identities = 85/544 (16%), Positives = 171/544 (31%), Gaps = 42/544 (8%)
Query 84 RTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
+A+ + ++ +I++ N IT P P+ + + +R
Sbjct 943 NSATIIDIHPSSTYSIRMYAKNRIGKSEPSNEITITADEAAPDGPPQEVHLEPTSSQSIR 1002
Query 144 CEWDGGRET-------HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV 196
W ++ + + S +F + + F +
Sbjct 1003 VTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISIDTTGDSEVYTLDNLNKFTQYGL 1062
Query 197 WVEAENALGKVTSDH-INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK--SVI 253
V+A N G S I + V PP N+ I + + ++W+ S + + I
Sbjct 1063 VVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIAT--SPESISISWSTLSKEALNGI 1120
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ + + Y + ++ +T+ S + L+ +T Y ++ G G
Sbjct 1121 LQGFRVIY-WANLIDGELGEIKNVTTTQPSLELDGLEKYTNYSIQVLAFTRAGDGV---R 1176
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT-R 372
SE+ T ED P + V + W LPP + NG I Y V +
Sbjct 1177 SEQIFTRTKEDVPGPPAGVKAAAASASM-----VFVSW--LPPLKLNGIIRKYTVFCSHP 1229
Query 373 WKSHLQNYTVNATKLTVNLTN----DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+ + + + + + + N +Y + G+ +++ + +A ++
Sbjct 1230 YPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPARIL 1289
Query 429 DLKAFPKD---NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW--QQEDGTVHRTYLR 483
+ + + ++W S+ P + ++ + +R
Sbjct 1290 TFSGTVTTPWMKDIVLPCKAVGDPSPA--VKWMKDSNGTPSLVTIDGRRSIFSNGSFVIR 1347
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLP 543
AE Y A+ + I L+ P P + K + L W LP
Sbjct 1348 TVKAEDSGY----YSCVANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSITLSW--LP 1401
Query 544 VDVQNGFIRNYTIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
D IR Y + Y + + S Y L +L T Y + A G
Sbjct 1402 GDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGR 1461
Query 603 GPEF 606
E
Sbjct 1462 ISEI 1465
Score = 145 bits (366), Expect = 5e-34, Method: Composition-based stats.
Identities = 96/552 (17%), Positives = 174/552 (32%), Gaps = 59/552 (11%)
Query 99 IQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLET-- 156
+ CN G Q + T+ +P P+N+ I + + W + L
Sbjct 1063 VVQACNRAGTGPSSQEIITTTLE-DVPSYPPENVQAIATSPESISISWSTLSKEALNGIL 1121
Query 157 ---NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN 213
+ + + K T S +D + N + V A G
Sbjct 1122 QGFRVIYWANLIDGELGEIKNVTTTQPSLELDGLE-KYTNYSIQVLAFTRAGDGVRSEQI 1180
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
F + P PP V + +S++ ++W P + II KY + + I
Sbjct 1181 FTRTKEDVPGPPA--GVKAAAASASMVFVSWLPPLKLNGIIRKYTVFC---SHPYPTVIS 1235
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS------ 327
+ + S+ + +L +Y + + G+G + SE + P+
Sbjct 1236 EFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRG---NSSEIITVEPLAKAPARILTFS 1292
Query 328 ---KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA 384
P + P G + + W ++NG + R ++ +
Sbjct 1293 GTVTTPWMKDIVLPCKAVGDPSPAVKWM----KDSNGTPSLVTIDGRRSIFSNGSFVIRT 1348
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
K D + N G SD +L + P + + + + + W
Sbjct 1349 VKA-----EDSGYYSCVANNNWG-SDEIILNLQV-QVPPDQPRLTVSKT-TSSSITLSWL 1400
Query 445 TPRE---SVKKYILEWCVLSDKAPCITDWQQEDGT-VHRTYLRGNLAESKCYLITVTPVY 500
S++ YIL++ + + W + R+Y NL Y T+T
Sbjct 1401 PGDNGGSSIRGYILQYSEDNSE-----QWGSFPISPSERSYRLENLKCGTWYKFTLTAQN 1455
Query 501 ADGPGS-PESIKAYL--KQAPPSKGPTVRTKKVGKNEAVLE---WDQLPVDVQNGFIRNY 554
GPG E I+A K+ SK + + L W+ I ++
Sbjct 1456 GVGPGRISEIIEAKTLGKEPQFSKEQELFA-SINTTRVRLNLIGWND-----GGCPITSF 1509
Query 555 TIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKF 613
T+ YR T S Y L L T Y ++M G + + F T +
Sbjct 1510 TLEYRPFGTTVWTTAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCAE-KQANFATLNY 1568
Query 614 AQGEIEAIVVPV 625
I ++ V
Sbjct 1569 DGSTIPPLIKSV 1580
Score = 79.1 bits (193), Expect = 1e-13, Method: Composition-based stats.
Identities = 45/245 (18%), Positives = 81/245 (33%), Gaps = 23/245 (9%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A N G SD I + +V P+ P L+V + SS + L+W I Y +
Sbjct 1361 ANNNWG---SDEIILNLQVQVPPDQPR-LTVSKT--TSSSITLSWLPGDNGGSSIRGYIL 1414
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
QY ++ W P + + S+ +++LK T Y F + G G SE
Sbjct 1415 QYSEDNSEQWGSFP---ISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRI---SEIIEA 1468
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN 379
T P + + T+ + + W + I + + + + +
Sbjct 1469 KTLGKEPQFSKEQELFASINTTRVRLNL-IGW-----NDGGCPITSFTLEYRPFGTTVWT 1522
Query 380 YTVNATKLTVNLTNDRYLAT-----LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP 434
+ + D AT + V N G ++ +T P +
Sbjct 1523 TAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLIKSVVQ 1582
Query 435 KDNML 439
+ L
Sbjct 1583 SEEGL 1587
Score = 64.5 bits (155), Expect = 4e-09, Method: Composition-based stats.
Identities = 98/627 (16%), Positives = 184/627 (29%), Gaps = 101/627 (16%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASS----V 89
VV + VC +K + W + I K I++ +S V
Sbjct 414 SEKVVSPAEPVSLVCNVK-------GTPLPTVTWTLDDDPILKGSGHRISQMITSEGNVV 466
Query 90 TFTDIASLNIQLTCNILTFGQLEQNV--YGITIISGLPPE-KP-KNLSCIVNEGKKMRCE 145
++ +I+S ++ V Y I P +P KN++ I + C
Sbjct 467 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHC- 525
Query 146 WDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV----NIEVWVEAE 201
R +++K + + + T+ S V V +
Sbjct 526 ----RVIGYPY-YSIKWYKNANLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQ 580
Query 202 NALGKVTSDHINFDPVYKVKPN--PPHNLS-------VINSEELSSILKLTWTNPSIKSV 252
L S H+ ++P P ++ V+ S +L + +TW
Sbjct 581 PQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLP--ITITWQKDGRPIP 638
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP--FTEYVFRIRCMKEDGKGYW 310
L I D SS + +L Y C+ +
Sbjct 639 ASLGVTI----------------DNIDFTSSLRISNLSLMHNGNYT----CIARNEAAAV 678
Query 311 SDWSEEASGITY----EDRPSKAPSFWYKIDPSHTQGYRTVQLVWK-----TLPPFEA-- 359
S+ + + R I +GY +VWK +P F+
Sbjct 679 EHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIA 738
Query 360 -NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL-TVRNLVGK--SDAAVLT 415
NG+I N + L ++ + L V N VG S + LT
Sbjct 739 LNGRIQ---------------VLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 783
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
+ ++P L + + + + ++ E +++ + +E G
Sbjct 784 VKIPAMITSYPNTTLATQGQRKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVG 843
Query 476 T--VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN 533
+ + + E + + + + G I+ +++ P P + K V
Sbjct 844 EEVISTLQILPTVREDSGF-FSCHAINSYGE-DRGIIQLTVQE--PPDPPEIEIKDVKAR 899
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN----VDSSHTEYTLSSLTSDTLYM 589
L W N I Y I + + + V T+ + + Y
Sbjct 900 TITLRWTMG--FDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYS 957
Query 590 VRMAAYTDEG-GKDGPEFTFTTPKFAQ 615
+RM A G + E T T + A
Sbjct 958 IRMYAKNRIGKSEPSNEITITADEAAP 984
Score = 38.7 bits (88), Expect = 0.30, Method: Composition-based stats.
Identities = 22/152 (14%), Positives = 44/152 (29%), Gaps = 21/152 (14%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTI-PKEQYTIINRTASSV 89
ISP + S + C + + W N + P + I +++
Sbjct 318 ISPRKVKSSVGSQVSLSCSVTGN-------EDQELSWYRNGEILNPGKNVRITGLNHANL 370
Query 90 TFTDIASLNIQ-LTCNILTFGQLEQNVYGITIISGLP------------PEKPKNLSCIV 136
+ + C + Q+ + + G P P +P +L C V
Sbjct 371 IMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLVCNV 430
Query 137 NEGKKMRCEWDGGRETHLETNFTLKSEWATHK 168
W + L+ + S+ T +
Sbjct 431 KGTPLPTVTWTLDDDPILKGSGHRISQMITSE 462
>sp|O60469|DSCAM_HUMAN Cell adhesion molecule DSCAM OS=Homo sapiens
OX=9606 GN=DSCAM PE=1 SV=2
Length=2012
Score = 239 bits (609), Expect = 7e-64, Method: Composition-based stats.
Identities = 112/595 (19%), Positives = 204/595 (34%), Gaps = 91/595 (15%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLET----NFTLKSEWATHK------FADCKAKRDTP 179
K +SC + K + W+ +E + + + ++ + +
Sbjct 805 KEMSCTAHGEKPIIVRWE--KEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGF 862
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
SC A N+ G+ D + P+PP + + +
Sbjct 863 FSCH----------------AINSYGE---DRGIIQLTVQEPPDPPE---IEIKDVKART 900
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ L WT + I Y+I+ + K S S +D + +S T+ D+ P + Y R+
Sbjct 901 ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRM 960
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
GK S+ S E + E P P ++P +Q ++++ WK
Sbjct 961 YAKNRIGK---SEPSNELTITADEAAPDGPPQ-EVHLEPISSQ---SIRVTWKAPKKHLQ 1013
Query 360 NGKILDYEVTLTRWKSHLQ--------NYTVNATKLTVNLTN--DRYLATLTVRNLVGKS 409
NG I Y++ + + + + ++ T++ N +Y + N G
Sbjct 1014 NGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTG 1073
Query 410 DAA--VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI------LEWCVLS 461
++ ++T D + P + + W+T + I + W L
Sbjct 1074 PSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLM 1133
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPS 520
D + + + T + L + Y I V G G E I K+ P
Sbjct 1134 DGE--LGEIKNIT-TTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPG 1190
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF----YRTIIGNETAVNVDSSHTE 576
V+ + + W LP NG IR YT+F Y T+I E + DS
Sbjct 1191 PPAGVKAAAASASMVFVSW--LPPLKLNGIIRKYTVFCSHPYPTVIS-EFEASPDS--FS 1245
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLG 636
Y + +L+ + Y V + A T G + E P P + T+
Sbjct 1246 YRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAK--------APARILTFSGTVTT 1297
Query 637 VLFCFNKRDLIKKHIWP--NVPDPSKS-HIAQWSPHTPPRHNFNSKDQMYSDGNF 688
+K + P V DPS + + S TP + + ++S+G+F
Sbjct 1298 --------PWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSF 1344
Score = 168 bits (424), Expect = 5e-41, Method: Composition-based stats.
Identities = 85/544 (16%), Positives = 171/544 (31%), Gaps = 42/544 (8%)
Query 84 RTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
+A+ + ++ +I++ N IT P P+ + + +R
Sbjct 943 NSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIR 1002
Query 144 CEWDGGRET-------HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV 196
W ++ + + S +F + + F +
Sbjct 1003 VTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGL 1062
Query 197 WVEAENALGKVTSDH-INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK--SVI 253
V+A N G S I + V PP N+ I + + ++W+ S + + I
Sbjct 1063 VVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIAT--SPESISISWSTLSKEALNGI 1120
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ + + Y + ++ +T+ S + L+ +T Y ++ G G
Sbjct 1121 LQGFRVIY-WANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGV---R 1176
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT-R 372
SE+ T ED P + V + W LPP + NG I Y V +
Sbjct 1177 SEQIFTRTKEDVPGPPAGVKAAAASASM-----VFVSW--LPPLKLNGIIRKYTVFCSHP 1229
Query 373 WKSHLQNYTVNATKLTVNLTN----DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+ + + + + + + N +Y + G+ +++ + +A ++
Sbjct 1230 YPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPARIL 1289
Query 429 DLKAFPKD---NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW--QQEDGTVHRTYLR 483
+ + + ++W S+ P + ++ + +R
Sbjct 1290 TFSGTVTTPWMKDIVLPCKAVGDPSPA--VKWMKDSNGTPSLVTIDGRRSIFSNGSFIIR 1347
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLP 543
AE Y A+ + I L+ P P + K + L W LP
Sbjct 1348 TVKAEDSGY----YSCIANNNWGSDEIILNLQVQVPPDQPRLTVSKTTSSSITLSW--LP 1401
Query 544 VDVQNGFIRNYTIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
D IR Y + Y + + S Y L +L T Y + A G
Sbjct 1402 GDNGGSSIRGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGR 1461
Query 603 GPEF 606
E
Sbjct 1462 ISEI 1465
Score = 145 bits (366), Expect = 4e-34, Method: Composition-based stats.
Identities = 96/552 (17%), Positives = 174/552 (32%), Gaps = 59/552 (11%)
Query 99 IQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLET-- 156
+ CN G Q + T+ +P P+N+ I + + W + L
Sbjct 1063 VVQACNRAGTGPSSQEIITTTLE-DVPSYPPENVQAIATSPESISISWSTLSKEALNGIL 1121
Query 157 ---NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN 213
+ + + K T S +D + N + V A G
Sbjct 1122 QGFRVIYWANLMDGELGEIKNITTTQPSLELDGLE-KYTNYSIQVLAFTRAGDGVRSEQI 1180
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
F + P PP V + +S++ ++W P + II KY + + I
Sbjct 1181 FTRTKEDVPGPPA--GVKAAAASASMVFVSWLPPLKLNGIIRKYTVFC---SHPYPTVIS 1235
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS------ 327
+ + S+ + +L +Y + + G+G + SE + P+
Sbjct 1236 EFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRG---NSSEIITVEPLAKAPARILTFS 1292
Query 328 ---KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA 384
P + P G + + W ++NG + R ++ +
Sbjct 1293 GTVTTPWMKDIVLPCKAVGDPSPAVKWM----KDSNGTPSLVTIDGRRSIFSNGSFIIRT 1348
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
K D + N G SD +L + P + + + + + W
Sbjct 1349 VKA-----EDSGYYSCIANNNWG-SDEIILNLQV-QVPPDQPRLTVSKT-TSSSITLSWL 1400
Query 445 TPRE---SVKKYILEWCVLSDKAPCITDWQQEDGT-VHRTYLRGNLAESKCYLITVTPVY 500
S++ YIL++ + + W + R+Y NL Y T+T
Sbjct 1401 PGDNGGSSIRGYILQYSEDNSE-----QWGSFPISPSERSYRLENLKCGTWYKFTLTAQN 1455
Query 501 ADGPGS-PESIKAYL--KQAPPSKGPTVRTKKVGKNEAVLE---WDQLPVDVQNGFIRNY 554
GPG E I+A K+ SK + + L W+ I ++
Sbjct 1456 GVGPGRISEIIEAKTLGKEPQFSKEQELFA-SINTTRVRLNLIGWND-----GGCPITSF 1509
Query 555 TIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKF 613
T+ YR T S Y L L T Y ++M G + + F T +
Sbjct 1510 TLEYRPFGTTVWTTAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCAE-KQANFATLNY 1568
Query 614 AQGEIEAIVVPV 625
I ++ V
Sbjct 1569 DGSTIPPLIKSV 1580
Score = 79.5 bits (194), Expect = 1e-13, Method: Composition-based stats.
Identities = 44/245 (18%), Positives = 80/245 (33%), Gaps = 23/245 (9%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A N G SD I + +V P+ P L+V + SS + L+W I Y +
Sbjct 1361 ANNNWG---SDEIILNLQVQVPPDQPR-LTVSKT--TSSSITLSWLPGDNGGSSIRGYIL 1414
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
QY ++ W P + + S+ +++LK T Y F + G G SE
Sbjct 1415 QYSEDNSEQWGSFP---ISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRI---SEIIEA 1468
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN 379
T P + + T+ + + W + I + + + + +
Sbjct 1469 KTLGKEPQFSKEQELFASINTTRVRLNL-IGW-----NDGGCPITSFTLEYRPFGTTVWT 1522
Query 380 YTVNATKLTVNLTNDR-----YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP 434
+ + D Y + V N G ++ +T P +
Sbjct 1523 TAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLIKSVVQ 1582
Query 435 KDNML 439
+ L
Sbjct 1583 NEEGL 1587
Score = 68.7 bits (166), Expect = 2e-10, Method: Composition-based stats.
Identities = 98/626 (16%), Positives = 183/626 (29%), Gaps = 99/626 (16%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASS----V 89
VV + +C +K I W + I K I++ +S V
Sbjct 414 SEKVVSPAEPVSLMCNVK-------GTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 466
Query 90 TFTDIASLNIQLTCNILTFGQLEQNV--YGITIISGLPPE-KP-KNLSCIVNEGKKMRCE 145
++ +I+S ++ V Y I P +P KN++ I + C
Sbjct 467 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHC- 525
Query 146 WDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV----NIEVWVEAE 201
R +++K ++ + + T+ S V V +
Sbjct 526 ----RVIGYPY-YSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQ 580
Query 202 NALGKVTSDHINFDPVYKVKPN--PPHNLS-------VINSEELSSILKLTWTNPSIKSV 252
L S H+ ++P P ++ V+ S +L + +TW
Sbjct 581 PQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLP--ITITWQKDGRPIP 638
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP--FTEYVFRIRCMKEDGKGYW 310
L I D SS + +L Y C+ +
Sbjct 639 GSLGVTI----------------DNIDFTSSLRISNLSLMHNGNYT----CIARNEAAAV 678
Query 311 SDWSEEASGITY----EDRPSKAPSFWYKIDPSHTQGYRTVQLVWK-----TLPPFEA-- 359
S+ + + R I +GY +VWK +P F+
Sbjct 679 EHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIA 738
Query 360 -NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL-TVRNLVGK--SDAAVLT 415
NG+I N + L ++ + L V N VG S + LT
Sbjct 739 LNGRIQ---------------VLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 783
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDK-APCITDWQQED 474
+ ++P L + + + + ++ E +++ + A + ++
Sbjct 784 VKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVG 843
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE 534
V T + + + G I+ +++ P P + K V
Sbjct 844 EEVISTLQILPTVREDSGFFSCHAINSYGE-DRGIIQLTVQE--PPDPPEIEIKDVKART 900
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN----VDSSHTEYTLSSLTSDTLYMV 590
L W N I Y I + + + V T+ + + Y +
Sbjct 901 ITLRWTMG--FDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSI 958
Query 591 RMAAYTDEG-GKDGPEFTFTTPKFAQ 615
RM A G + E T T + A
Sbjct 959 RMYAKNRIGKSEPSNELTITADEAAP 984
>sp|Q02173|MPSF_CHICK M-protein, striated muscle OS=Gallus gallus
OX=9031 PE=2 SV=1
Length=1450
Score = 235 bits (600), Expect = 7e-63, Method: Composition-based stats.
Identities = 119/705 (17%), Positives = 210/705 (30%), Gaps = 82/705 (12%)
Query 41 HSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIIN--RTASSVTFTDIASLN 98
T C + W + I ++T + ++++FT + +
Sbjct 280 GETLTLKCSV--LVTPELKRLRPRAEWYRDDVLIKDSKWTKLYFGEGQAALSFTHLNKDD 337
Query 99 IQLTCNILTFGQLEQNVYGITIISGLP-------PEKPKNLSCIVNEGKKMRCEWDGGRE 151
L + + N + P P ++ C + W
Sbjct 338 EGLY-TLRMVTKGGVNECSAFLFVRDADALIAGAPGAPMDVKCHDANRDYVIVTWKPPNT 396
Query 152 THLET---NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV--NIEVWVEAENALGK 206
T F K E + C D P T + + V A N+ G
Sbjct 397 TSQNPVIGYFVDKCEVGLENWVQC---NDAPVKICKYPVTGLYEGRSYIFRVRAVNSAGI 453
Query 207 VTS----------DHINFDPVYKVK--------------------PNPPHNLSVINSEEL 236
D ++ + V P PP N V SE
Sbjct 454 SRPSRVSEPVAALDPVDLERTQTVHVDEGRKIVISKDDLEGDIQIPGPPTN--VHASEIS 511
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
+ + L+W P + L Y I+ + +W ++ + A + V DL YV
Sbjct 512 KTYVVLSWDPPVPRGREPLTYFIEKSMVGSGSWQRVNAQ-VAVKSPRYAVFDLAEGKPYV 570
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW-KTLP 355
FR+ + G S+ +E PS + +V + W K
Sbjct 571 FRVLSANKHGISDPSEITEPIQPQDIVVVPSAP-----GRVVATRNTKTSVVVQWDKPKH 625
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL--TNDRYLATLTVRNLVGKSD--- 410
G +DY V + + +N + V+ T ++Y+ + N VG S+
Sbjct 626 EENLYGYYIDYSVVGSNQWEPANHKPINYNRFVVHGLETGEQYIFRVKAVNAVGFSENSQ 685
Query 411 --AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCIT 468
A+ A + + L +M + W P+ S IL + + +A
Sbjct 686 ESEAIKVQAALTCPSYPHGITLLNCDGHSMT-LGWKAPKYSGGSPILGYYIDKREA-NHK 743
Query 469 DWQQEDGTVHRT--YLRGNLAESKCYLITVTPVYADGPGS---PESIKAYLKQAPPSKGP 523
+W + + +V Y +L E Y + G G P P GP
Sbjct 744 NWHEVNSSVISRTIYTVEDLTEDAFYEFKIAAANVVGIGHPSDPSEHFKCKAWTMPEPGP 803
Query 524 --TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTL 579
+ +V VL W PV I Y + Y+ + + TA +SH + +
Sbjct 804 AYDLTVCEVRNTSLVLLWKA-PVYEGKSPITGYLVDYKEVDTEDWITANEKPTSHRYFKV 862
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLF 639
+ L Y+ ++ A D G E + P F + + + LG
Sbjct 863 TDLHQGHTYVFKVRAVNDAGVGKSSE--ISEPVFVEASPGTKEIFSGVDEEGNIYLGFEC 920
Query 640 --CFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQM 682
+ + + + D K I H+ K +
Sbjct 921 KEATDASHFLWGKSYEEIEDSDKFKIETKGDHSKLYFKHPDKSDL 965
>sp|Q5VWK5|IL23R_HUMAN Interleukin-23 receptor OS=Homo sapiens
OX=9606 GN=IL23R PE=1 SV=3
Length=629
Score = 226 bits (575), Expect = 3e-62, Method: Composition-based stats.
Identities = 75/333 (23%), Positives = 133/333 (40%), Gaps = 24/333 (7%)
Query 3 TLQTWLVQALFIFLTTESTGELLDPCG---YISPESPVVQLHSNFTAVCVLKEKCMDYFH 59
T+Q V AL+I + G C ++ P + + ++ N + C K
Sbjct 5 TIQWDAVIALYILFSWCHGGITNINCSGHIWVEP-ATIFKMGMNISIYCQAAIKN----- 58
Query 60 VNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQN-VYGI 118
+ + N + Q T IN+T + + + + + + C ++ + G
Sbjct 59 CQPRKLHFYKNGIK-ERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGK 117
Query 119 TIISGLPPEKPKNLSCIVNE-GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD 177
I SG PP+ P ++C++ E M C W+ G+ T+++T + + K + + ++
Sbjct 118 DISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHV-----KSLETEEEQQ 172
Query 178 TPTSCTVDYSTVYFVN---IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
TS ++ ST VWV+A NALG S + V P+
Sbjct 173 YLTSSYINISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETIN 232
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ W S ++ + ++Y+ TW+ + DT T + L+P +
Sbjct 233 ATVPKTIIYWD--SQTTIEKVSCEMRYKATTNQTWN-VKEFDTNFTYVQQSEFYLEPNIK 289
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
YVF++RC E GK YW WS T E P
Sbjct 290 YVFQVRCQ-ETGKRYWQPWSSLFFHKTPETVPQ 321
Score = 41.8 bits (96), Expect = 0.036, Method: Composition-based stats.
Identities = 15/106 (14%), Positives = 29/106 (27%), Gaps = 4/106 (4%)
Query 518 PPSKGPTVRTKKVG-KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
PP V W+ + Y + +++ E + SS+
Sbjct 124 PPDIPDEVTCVIYEYSGNMTCTWNAGKLTY---IDTKYVVHVKSLETEEEQQYLTSSYIN 180
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIV 622
+ SL Y+V + A G ++ + I
Sbjct 181 ISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVIS 226
>sp|Q12860|CNTN1_HUMAN Contactin-1 OS=Homo sapiens OX=9606 GN=CNTN1
PE=1 SV=1
Length=1018
Score = 231 bits (588), Expect = 6e-62, Method: Composition-based stats.
Identities = 77/383 (20%), Positives = 130/383 (34%), Gaps = 24/383 (6%)
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS--QIPPEDTASTRSSFTVQDLK 290
+ ++ + LTW+ S I KY IQ +T + W + P + DL
Sbjct 613 EDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLI 672
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
P+ EY FR+ G+G S S T P+ APS R + +
Sbjct 673 PWMEYEFRVVATNTLGRGEPSIPSN--RIKTDGAAPNVAPSDVGG----GGGRNRELTIT 726
Query 351 WKTLPPFEANGKILDYEVTL-----TRWKSHLQNYTVNATKL---TVNLTNDRYLATLTV 402
W L G Y V WK + + + +
Sbjct 727 WAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKA 786
Query 403 RNLVGKSDAAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK-YILEWCV 459
N G +++ + A D + P + + V W E + + Y + +
Sbjct 787 FNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESYQIRYWA 846
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-IKAYLKQAP 518
DK Q + NL Y I V + G G P I+A+ K+AP
Sbjct 847 AHDKEEAANRVQVTS--QEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAP 904
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
PS+ P + + + ++ WD + + Y + YR ++ + S+H
Sbjct 905 PSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKLY--STHKHSI 962
Query 579 LSSLTSDTLYMVRMAAYTDEGGK 601
+ D Y+V + A++D G
Sbjct 963 EVPIPRDGEYVVEVRAHSDGGDG 985
Score = 122 bits (305), Expect = 5e-27, Method: Composition-based stats.
Identities = 53/394 (13%), Positives = 123/394 (31%), Gaps = 42/394 (11%)
Query 140 KKMRCEWDGGRETHLE-TNFTLKSEW-ATHKFADCKAK---RDTPTSCTVDYSTVYFVNI 194
+ W G + H + +T++++ + + D K + + ++
Sbjct 618 TSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEY 677
Query 195 EVWVEAENALGKV-TSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSV 252
E V A N LG+ S N PN P ++ + L +TW S +
Sbjct 678 EFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVG--GGGGRNRELTITWAPLSREYH 735
Query 253 I--ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
Y + ++ D W ++ + + R + + P T + +++ G G +
Sbjct 736 YGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPY 795
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S A + +D PS+AP+ + + W+ + + Y++
Sbjct 796 SLV---AVINSAQDAPSEAPTEVGV----KVLSSSEISVHWEHVLEK----IVESYQIRY 844
Query 371 TRWKSHLQ-------NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQ 422
+ + +L L + +Y + N G + ++
Sbjct 845 WAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAP 904
Query 423 ATHPVMDLKAFPKDNMLWVEWTTP-----RESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
+ P + + + + W +V Y + + + +
Sbjct 905 PSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKL-------YST 957
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
H+ + + Y++ V G G +K
Sbjct 958 HKHSIEVPIPRDGEYVVEVRAHSDGGDGVVSQVK 991
Score = 51.4 bits (121), Expect = 4e-05, Method: Composition-based stats.
Identities = 40/250 (16%), Positives = 77/250 (31%), Gaps = 18/250 (7%)
Query 67 WKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPP 126
WK T P + S + + +++ V I P
Sbjct 754 WKKVTVTNPDTGRYVHKDETMSPS----TAFQVKVKAFNNKGDGPYSLVAVINSAQDAPS 809
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
E P + V ++ W+ E +E ++ ++ WA H + + +
Sbjct 810 EAPTEVGVKVLSSSEISVHWEHVLEKIVE-SYQIRY-WAAHDKEEAANRVQVTSQEYSAR 867
Query 187 STVYF--VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ V A N+ G + K P+ P + + + S + +TW
Sbjct 868 LENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRI-ISSVRSGSRYI-ITW 925
Query 245 TN--PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
+ + Y + YR Q + ++ + S V + EYV +R
Sbjct 926 DHVVALSNESTVTGYKVLYRPDG-----QHDGKLYSTHKHSIEVP-IPRDGEYVVEVRAH 979
Query 303 KEDGKGYWSD 312
+ G G S
Sbjct 980 SDGGDGVVSQ 989
>sp|Q64605|PTPRS_RAT Receptor-type tyrosine-protein phosphatase
S OS=Rattus norvegicus OX=10116 GN=Ptprs PE=1 SV=2
Length=1907
Score = 232 bits (592), Expect = 9e-62, Method: Composition-based stats.
Identities = 93/513 (18%), Positives = 168/513 (33%), Gaps = 43/513 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRET-----HLETNFTLKSEWATHKFADCKAKRDTP 179
P P+N+ + M +W+ E +T++ E +
Sbjct 413 PASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQ---KHNVDD 469
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSS 238
+ T S + V V A ++G SD I V P P NL E S
Sbjct 470 SLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGV-PGQPMNLRAEAKSETS- 527
Query 239 ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ L+W+ P +S ++KY + +R D T ++F V+DLKP TEY FR
Sbjct 528 -IGLSWSAPRQES--VIKYELLFREGDRGR----EVGRTFDPTTAFVVEDLKPNTEYAFR 580
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+ G G + + T + +PS P + + + W+ PP
Sbjct 581 LAARSPQGLGAF---TAVVRQRTLQAKPSAPPQDVK----CTSLRSTAILVSWRPPPPET 633
Query 359 ANGKILDYEVTLTRWKS------HLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSD 410
NG ++ Y V S + N T++ + Y T VG
Sbjct 634 HNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGP 693
Query 411 AAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTP-----RESVKKYILEW-CVLSD 462
+ + D + P + V W +P ++ Y + + +
Sbjct 694 ESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGA 753
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+A + + + NL Y ITV G G+ K + +
Sbjct 754 EARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGR 813
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
PT+ ++ + + W+ P D + Y + + + + + + +
Sbjct 814 PTLSVQQTPEGSLLARWEP-PADAAEDPVLGYRLQFGREDAAPATLELAAWERRF-AAPA 871
Query 583 TSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ 615
Y+ R+AA G + + P+ A
Sbjct 872 HKGATYVFRLAARGRAGLGEEASAALSIPEDAP 904
Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats.
Identities = 87/440 (20%), Positives = 165/440 (38%), Gaps = 42/440 (10%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A ++LG + + K P P V +E ++ + +TW + + Y I
Sbjct 300 AMSSLGVIEA---VAQITVKSLPKAPGTPVV--TENTATSITVTWDSG--NPDPVSYYVI 352
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+Y++K QI + T + +++ L P +EY + + G+G SE
Sbjct 353 EYKSKSQDGPYQIKEDIT---TTRYSIGGLSPNSEYEIWVSAVNSIGQG---PPSESVVT 406
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH--- 376
T E P+ AP + T+ + W+ P E NG I Y V T H
Sbjct 407 RTGEQAPASAPRNV----QARMLSATTMIVQWEE--PVEPNGLIRGYRVYYTMEPEHPVG 460
Query 377 -LQNYTVNATKLTV---NLTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLK 431
Q + V+ + LT L ++ Y + VG + + + P+
Sbjct 461 NWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRA 520
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
+ + + W+ PR+ ++++ +L + + + ++ +L +
Sbjct 521 EAKSETSIGLSWSAPRQES---VIKYELLFREGDRGREVGR-TFDPTTAFVVEDLKPNTE 576
Query 492 YLITVTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y + G G+ ++ QA PS P V+ + ++ W P + NG
Sbjct 577 YAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNG 636
Query 550 FIRNYTIFYRTIIGNETAV----NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ Y++ YR + + N+ + T+ L +L T Y V AYT+ G GPE
Sbjct 637 ALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVG--PGPE 694
Query 606 FTFTTPKFAQGEIEAIVVPV 625
+ P + + + P
Sbjct 695 SS---PVVVRTDEDVPSAPP 711
Score = 224 bits (570), Expect = 5e-59, Method: Composition-based stats.
Identities = 107/594 (18%), Positives = 189/594 (32%), Gaps = 56/594 (9%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
I P S + N CV Y+ W + E + R +T
Sbjct 236 ILPMSHEIMPGGNVNITCV-------AVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELT 288
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
+ TC ++ + + V IT+ S P+ P N + WD G
Sbjct 289 ---DVKDSANYTCVAMSSLGVIEAVAQITVKS--LPKAPGTPVVTENTATSITVTWDSGN 343
Query 151 ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-TS 209
++ + + + + K D T+ E+WV A N++G+ S
Sbjct 344 PD--PVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPS 401
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA--- 266
+ + + + P N+ + I++ W P + +I Y + Y +
Sbjct 402 ESVVTRTGEQAPASAPRNVQARMLSATTMIVQ--WEEPVEPNGLIRGYRVYYTMEPEHPV 459
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
W + +D+ T TV L Y R+ G G SD T + P
Sbjct 460 GNWQKHNVDDSLLT----TVGSLLEDETYTVRVLAFTSVGDGPLSD---PIQVKTQQGVP 512
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ--NYTVNA 384
+ + + + ++ L W ++ YE+ +
Sbjct 513 GQPMNLR-----AEAKSETSIGLSWSAPRQE----SVIKYELLFREGDRGREVGRTFDPT 563
Query 385 TKLTVN--LTNDRYLATLTVRNLVGKSDA-AVLTIPACDFQATHPVMDLKAFP-KDNMLW 440
T V N Y L R+ G AV+ + + P D+K + +
Sbjct 564 TAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAIL 623
Query 441 VEWTTPR-----ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLIT 495
V W P ++ Y + + L + P + T L L + Y +T
Sbjct 624 VSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTT-QILLEALEKWTEYRVT 682
Query 496 VTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
GPG + + PS P V + + + W Q+G IR
Sbjct 683 AVAYTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRG 742
Query 554 YTIFYRTIIGNETAVNVD------SSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
Y + Y + G E + E +++L +T Y + +AAYT +G
Sbjct 743 YQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKGDG 796
Score = 207 bits (526), Expect = 1e-53, Method: Composition-based stats.
Identities = 100/656 (15%), Positives = 187/656 (29%), Gaps = 63/656 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGR-ETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P +P NL + W R E+ ++ + + + PT+
Sbjct 511 VPGQPMNLRAEAKSETSIGLSWSAPRQESVIKYELLFREGDRGREV----GRTFDPTTAF 566
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
V + A + G + + KP+ P V + S+ + ++
Sbjct 567 VVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAP-PQDVKCTSLRSTAILVS 625
Query 244 WTNPSIK--SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
W P + + ++ Y+++YR + + T + ++ L+ +TEY
Sbjct 626 WRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVA 685
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
E G G S T ED PS P + ++++W++ P +G
Sbjct 686 YTEVGPGPESS---PVVVRTDEDVPSAPPRKVE----AEALNATAIRVLWRSPTPGRQHG 738
Query 362 KILDYEVTLTRWKSHLQNYT----------VNATKLTVNLTNDRYLATLTVRNLVGKSDA 411
+I Y+V R + +T Y T+ + G
Sbjct 739 QIRGYQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKGDGAR 798
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
+ + + L W P ++ + +L + + +
Sbjct 799 SKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPADAAEDPVLGYRLQFGREDAAPATL 858
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV--RTKK 529
+ R + + Y+ + G G S + + P P +
Sbjct 859 ELAAWERRFAAPAH--KGATYVFRLAARGRAGLGEEASAALSIPEDAPRGFPQILGAAGN 916
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-------TAVNVDSSHTEYTLSSL 582
V +L W +NG I YT+ R A + T TL L
Sbjct 917 VSAGSVILRWLPPVPAERNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLQGL 976
Query 583 TSDTLYMVRMAAYTDEGGKD-GPEFTFTT------PKFAQGEIEAIV------------- 622
+T Y +R+ A+T G P + PK + ++
Sbjct 977 RPETAYELRVRAHTRRGPGPFSPPLRYRLARDPVSPKNFKVKMIMKTSVLLSWEFPDNYN 1036
Query 623 VPVCLAFLLTTLLGVLFCFNKRDLI----KKHIWPNVPDPSKSHIAQWSPHTPPRHNFNS 678
P L + + LI + V S + R FN
Sbjct 1037 SPTPYKIQYNGLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTARTAFNM 1096
Query 679 KDQMYSDGNFTDV--SVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSS 732
S D S+V + + P + + K G + GS
Sbjct 1097 LSGKPSVAPKPDNDGSIVVYLPDGQSPVTVQNYFIVMVPLRKSRG-GQFPILLGSP 1151
Score = 166 bits (421), Expect = 1e-40, Method: Composition-based stats.
Identities = 81/509 (16%), Positives = 148/509 (29%), Gaps = 45/509 (9%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN---FTLKSEWATHKFADCKAKRDTP- 179
P P+++ C + W ++++ + D K + P
Sbjct 604 KPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPP 663
Query 180 -TSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELS 237
T+ + + + V A +G S + V PP V +
Sbjct 664 TTTQILLEALEKWTEYRVTAVAYTEVGPGPESSPVVVRTDEDVPSAPPR--KVEAEALNA 721
Query 238 SILKLTWTNPSIK--SVIILKYNIQY-RTKDASTWSQIPPEDT-ASTRSSFTVQDLKPFT 293
+ +++ W +P+ I Y + Y R + A +D + + +L+P T
Sbjct 722 TAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPET 781
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
Y + G G S + + P+ + P + R W+
Sbjct 782 AYSITVAAYTMKGDGARSKP----KVVVTKGAVLGRPTLSVQQTPEGSLLAR-----WEP 832
Query 354 LPPFEANGKILDYEVTLTRWKSH--LQNYTVNATKLTVNLTNDR-YLATLTVR--NLVGK 408
P A +L Y + R + + Y+ L R +G+
Sbjct 833 -PADAAEDPVLGYRLQFGREDAAPATLELAAWERRFAAPAHKGATYVFRLAARGRAGLGE 891
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP-RESVKKYILEWCVLSDKA--- 464
+A L+IP + ++ + + W P I+++ V +A
Sbjct 892 EASAALSIPEDAPRGFPQILGAAGNVSAGSVILRWLPPVPAERNGAIIKYTVSVREAGAP 951
Query 465 ---PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
L Y + V GPG Y P
Sbjct 952 GPATETELAAAAQPGAETALTLQGLRPETAYELRVRAHTRRGPGPFSPPLRYRLARDPVS 1011
Query 522 GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS 581
+ K + K +L W+ D N Y I Y N ++VD T+ ++
Sbjct 1012 PKNFKVKMIMKTSVLLSWEF--PDNYNSP-TPYKIQY-----NGLTLDVDGRTTKKLITH 1063
Query 582 LTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
L T Y + T+ G G T
Sbjct 1064 LKPHTFYNFVL---TNRGSSLGGLQQTVT 1089
Score = 141 bits (355), Expect = 1e-32, Method: Composition-based stats.
Identities = 89/462 (19%), Positives = 161/462 (35%), Gaps = 86/462 (19%)
Query 200 AENALGKVTSD-HINFDPVYKVKPNPP-----HNLSVINSEELSSIL---------KLTW 244
A+N++G++T + ++ P P L V+ +++L ++TW
Sbjct 109 AQNSVGEITVHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITW 168
Query 245 ------TNPSIKSVIILKYN---IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+PS + I + +Q + + + + T S ++ P Y
Sbjct 169 FKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS----SPANLY 224
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
R+R AP F V +
Sbjct 225 -VRVR--------------------------RVAPRFSILPMSHEIMPGGNVNIT----- 252
Query 356 PFEANGKILDYEVTLTRWK--SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK-SDAA 412
A G + Y + + + + V L + D T + +G A
Sbjct 253 -CVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVA 311
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQ 471
+T+ + PV+ + V W + + V Y++E+ S P +Q
Sbjct 312 QITVKSLPKAPGTPVVT---ENTATSITVTWDSGNPDPVSYYVIEYKSKSQDGP----YQ 364
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-ESIKAYLKQAPPSKGP-TVRTKK 529
++ Y G L+ + Y I V+ V + G G P ES+ + P+ P V+ +
Sbjct 365 IKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARM 424
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFY----RTIIGNETAVNVDSSHTEYTLSSLTSD 585
+ +++W++ NG IR Y ++Y +GN NVD S T+ SL D
Sbjct 425 LSATTMIVQWEE--PVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLT-TVGSLLED 481
Query 586 TLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
Y VR+ A+T G DGP + P + + P+ L
Sbjct 482 ETYTVRVLAFTSVG--DGP---LSDPIQVKTQQGVPGQPMNL 518
Score = 116 bits (289), Expect = 8e-25, Method: Composition-based stats.
Identities = 86/545 (16%), Positives = 145/545 (27%), Gaps = 62/545 (11%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P P + + + + + N+ Q + + +T
Sbjct 628 PPPPETHNGALVGYSVRYRPLGSEDP--DPKEV----NNIPPTTTQILL----EALEKWT 677
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD---GG 149
+ + T + G V + +P P+ + +R W G
Sbjct 678 EYRVTAVAYT--EVGPGPESSPVV-VRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPG 734
Query 150 RETH----LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
R+ + ++ K V + + V A G
Sbjct 735 RQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKG 794
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTK 264
P LSV + E S L W P+ +L Y +Q+ +
Sbjct 795 DGARSKPKVVVTKGAVLGRPT-LSVQQTPEGS--LLARWEPPADAAEDPVLGYRLQFGRE 851
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
DA+ + A+ F YVFR+ G G + S S ED
Sbjct 852 DAAP----ATLELAAWERRFAAP-AHKGATYVFRLAARGRAGLGE--EASAALSI--PED 902
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH-------- 376
P P + +V L W P E NG I+ Y V++ +
Sbjct 903 APRGFPQILGA---AGNVSAGSVILRWLPPVPAERNGAIIKYTVSVREAGAPGPATETEL 959
Query 377 ---LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF 433
Q A L Y + G + P
Sbjct 960 AAAAQPGAETALTLQGLRPETAYELRVRAHTRRGPGPFSPPLRYRLARDPVSPKNFKVKM 1019
Query 434 PKDNMLWVEWTTPRE--SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
+ + W P S Y +++ L+ DG + L +L
Sbjct 1020 IMKTSVLLSWEFPDNYNSPTPYKIQYNGLTLD---------VDGRTTK-KLITHLKPHTF 1069
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
Y +T + G +++ A S P+V K V+ LP +
Sbjct 1070 YNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSVAPKPDNDGSIVV---YLPDGQSPVTV 1126
Query 552 RNYTI 556
+NY I
Sbjct 1127 QNYFI 1131
>sp|P52179|MYOM1_HUMAN Myomesin-1 OS=Homo sapiens OX=9606 GN=MYOM1
PE=1 SV=2
Length=1685
Score = 231 bits (589), Expect = 2e-61, Method: Composition-based stats.
Identities = 117/627 (19%), Positives = 204/627 (33%), Gaps = 78/627 (12%)
Query 41 HSNFTAVC--VLKEKCMDYFHVNANYIVWKTNHFTIPKEQY--TIINRTASSVTFTDIAS 96
+ C V+ + + I W N + ++ T+ + +++TF+ +
Sbjct 419 GETMSLGCRVVITPEIKHF----QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNK 474
Query 97 LNIQLTCNILTFGQLEQN------VYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD-GG 149
+ L + G+ + V P P ++ C+ + W
Sbjct 475 EDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPA 534
Query 150 RETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG-- 205
+ F K E T ++ C V + V A N +G
Sbjct 535 VDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGR-SYIFRVRAVNKMGIG 593
Query 206 ---KVTSDHINFDPVYKVK-------------------------PNPPHNLSVINSEELS 237
+V+ DP K + P PP +LSV +E
Sbjct 594 FPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSV--TEATR 651
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
S + L+W P + + Y ++ W ++ E F + DL Y F
Sbjct 652 SYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPV-KSPRFALFDLAEGKSYCF 710
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW-KTLPP 356
R+RC G G S+ +E D P KI PS +V + W ++
Sbjct 711 RVRCSNSAGVGEPSEATEVTVVGDKLDIPKAP----GKIIPSRNTDT-SVVVSWEESKDA 765
Query 357 FEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKS----D 410
E G ++ V + N V ++ T + +T Y+ + N G S D
Sbjct 766 KELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQD 825
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDK--APCIT 468
+ + + A P + + L E+ + +L K P +
Sbjct 826 SEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLP 885
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES--IKAYLKQAPPSKGPTVR 526
Q G + + + E +T P A G +S +K +APPS +
Sbjct 886 SSSQNLGQTEVSKVSETVQE----ELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDIT 941
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII----GNETAVNVDS-SHTEYTLSS 581
+ ++ VL W Q P + I Y + YR +I G NV + S Y +S+
Sbjct 942 CLESFRDSMVLGWKQ-PDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISN 1000
Query 582 LTSDTLYMVRMAAYTDEG-GKDGPEFT 607
L + +Y ++AA G G
Sbjct 1001 LKENMVYQFQVAAMNMAGLGAPSAVSE 1027
Score = 165 bits (416), Expect = 4e-40, Method: Composition-based stats.
Identities = 88/515 (17%), Positives = 156/515 (30%), Gaps = 32/515 (6%)
Query 121 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLET--NFTLKSEWATHKFADCKAKRDT 178
G+ P P +LS + W + E F K E T + +
Sbjct 633 SEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPV 692
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL-SVINSEELS 237
+ + + V N+ G V K + P +I S
Sbjct 693 KSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTD 752
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ + ++W S + ++ Y I+ + W P + S FT L Y+F
Sbjct 753 TSVVVSWEE-SKDAKELVGYYIEASVAGSGKWE--PCNNNPVKGSRFTCHGLVTGQSYIF 809
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV---QLVWKTL 354
R+R + G S++S+++ I + S S G T ++ +
Sbjct 810 RVRAVNAAGL---SEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVH-EAS 865
Query 355 PPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVL 414
PP +L + S QN + GKS + L
Sbjct 866 PPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPL 925
Query 415 TIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE----SVKKYILEWCVLSDKAPCITDW 470
+ P + + + W P + + Y + + + D P
Sbjct 926 KKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWRE 985
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY--LKQ---APPSKGPTV 525
Y NL E+ Y V + G G+P ++ ++ A P ++
Sbjct 986 ANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSL 1045
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA---VNVDSSHTEY-TLSS 581
+ +V K+ VL+W PV + Y + + E +N + Y +
Sbjct 1046 KCSEVRKDSLVLQWKP-PVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRG 1104
Query 582 LTSDTLYMVRMAAYTDEGGKD-----GPEFTFTTP 611
L Y+ R+ A G GP T P
Sbjct 1105 LKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRP 1139
Score = 93.0 bits (229), Expect = 9e-18, Method: Composition-based stats.
Identities = 49/215 (23%), Positives = 74/215 (34%), Gaps = 17/215 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRE-THLETNFTLKSEWATHKFADCKAKRDT 178
PP P +++C+ + M W GG E T N+ + K+ + K
Sbjct 933 PPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVK-AV 991
Query 179 PTSCTVDYSTVYFVNIEVWVEAEN--ALGKVTSDHINF--DPVYKVKPNPPHNLSVINSE 234
+ + + V A N LG ++ F + P PPH+L SE
Sbjct 992 SEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLK--CSE 1049
Query 235 ELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
L L W P + Y + + A + A V+ LK
Sbjct 1050 VRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGV 1109
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
YVFR+R + + G G SD A + E RP
Sbjct 1110 SYVFRVRAINQAGVGKPSD---LAGPVVAETRPGT 1141
Score = 72.6 bits (176), Expect = 1e-11, Method: Composition-based stats.
Identities = 47/302 (16%), Positives = 82/302 (27%), Gaps = 48/302 (16%)
Query 362 KILDYE----VTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
+I Y ++ ++W L + + D L T+ VR +
Sbjct 440 EIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFV 499
Query 418 ----ACDFQATHPVMDLK-AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQ 472
A A +D+K + + + W P IL + + W Q
Sbjct 500 RDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFID-KCEVGTDSWSQ 558
Query 473 EDGTVHRTYLR--GNLAESKCYLITVTPVYADGPGSPESI-------------------- 510
+ T + L E + Y+ V V G G P +
Sbjct 559 CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPS 618
Query 511 ------KAYLKQAP-----PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FY 558
++ P P + + ++ VL W G + Y +
Sbjct 619 APWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM--YFVEKC 676
Query 559 RTIIGNETAVN--VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
N VN + + L L Y R+ G + E T T +
Sbjct 677 EAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKL 736
Query 617 EI 618
+I
Sbjct 737 DI 738
>sp|P12960|CNTN1_MOUSE Contactin-1 OS=Mus musculus OX=10090 GN=Cntn1
PE=1 SV=1
Length=1020
Score = 228 bits (581), Expect = 6e-61, Method: Composition-based stats.
Identities = 76/383 (20%), Positives = 127/383 (33%), Gaps = 24/383 (6%)
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS--QIPPEDTASTRSSFTVQDLK 290
+ ++ + LTW+ S I KY IQ +T + W + P S DL
Sbjct 615 EDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMESAKAVDLI 674
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
P+ EY FR+ G G S S T P+ APS R + +
Sbjct 675 PWMEYEFRVVATNTLGTGEPSIPSN--RIKTDGAAPNVAPSDVGG----GGGTNRELTIT 728
Query 351 WKTLPPFEANGKILDYEVTL-----TRWKSHLQNYTVNATKL---TVNLTNDRYLATLTV 402
W L G Y V WK + + + +
Sbjct 729 WAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMTPSTAFQVKVKA 788
Query 403 RNLVGKSDAAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK-YILEWCV 459
N G +++ + A D + P + + V W E + + Y + +
Sbjct 789 FNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWKHVLEKIVESYQIRYWA 848
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-SIKAYLKQAP 518
DK Q + NL Y I V + G G I+ + ++AP
Sbjct 849 GHDKEAAAHRVQVTS--QEYSARLENLLPDTQYFIEVGACNSAGCGPSSDVIETFTRKAP 906
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
PS+ P + + + ++ WD + + Y I YR ++ + S+H
Sbjct 907 PSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKILYRPDGQHDGKL--FSTHKHSI 964
Query 579 LSSLTSDTLYMVRMAAYTDEGGK 601
+ D Y+V + A++D G
Sbjct 965 EVPIPRDGEYVVEVRAHSDGGDG 987
Score = 124 bits (312), Expect = 8e-28, Method: Composition-based stats.
Identities = 54/394 (14%), Positives = 120/394 (30%), Gaps = 42/394 (11%)
Query 140 KKMRCEWDGGRETHLE-TNFTLKSEW-ATHKFADCKAK---RDTPTSCTVDYSTVYFVNI 194
+ W G + H + +T++++ + + D K + + ++
Sbjct 620 TSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMESAKAVDLIPWMEY 679
Query 195 EVWVEAENALGKV-TSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSV 252
E V A N LG S N PN P ++ + L +TW S +
Sbjct 680 EFRVVATNTLGTGEPSIPSNRIKTDGAAPNVAPSDVG--GGGGTNRELTITWAPLSREYH 737
Query 253 I--ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
Y + ++ D W ++ + + R + + P T + +++ G G +
Sbjct 738 YGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMTPSTAFQVKVKAFNNKGDGPY 797
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S A + +D PS+AP+ + + WK + + Y++
Sbjct 798 SLV---AVINSAQDAPSEAPTEVGV----KVLSSSEISVHWKHVLEK----IVESYQIRY 846
Query 371 TRWKSHLQ-------NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQ 422
+ +L L + +Y + N G ++ V+
Sbjct 847 WAGHDKEAAAHRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPSSDVIETFTRKAP 906
Query 423 ATHPVMDLKAFPKDNMLWVEWTTP-----RESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
+ P + + + + W +V Y + + + +
Sbjct 907 PSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKILYRPDGQHDGKLFSTHKHS--- 963
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
+ + Y++ V G G +K
Sbjct 964 ----IEVPIPRDGEYVVEVRAHSDGGDGVVSQVK 993
Score = 55.2 bits (131), Expect = 3e-06, Method: Composition-based stats.
Identities = 43/250 (17%), Positives = 76/250 (30%), Gaps = 18/250 (7%)
Query 67 WKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPP 126
WK T P + T T + +++ V I P
Sbjct 756 WKKVTVTNPDTGRYVHKDE----TMTPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPS 811
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
E P + V ++ W E +E ++ ++ WA H + +
Sbjct 812 EAPTEVGVKVLSSSEISVHWKHVLEKIVE-SYQIRY-WAGHDKEAAAHRVQVTSQEYSAR 869
Query 187 STVYF--VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ V A N+ G S + K P+ P + + + S + +TW
Sbjct 870 LENLLPDTQYFIEVGACNSAGCGPSSDVIETFTRKAPPSQPPRI-ISSVRSGSRYI-ITW 927
Query 245 TN--PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
+ + Y I YR Q + ++ + S V + EYV +R
Sbjct 928 DHVVALSNESTVTGYKILYRPDG-----QHDGKLFSTHKHSIEVP-IPRDGEYVVEVRAH 981
Query 303 KEDGKGYWSD 312
+ G G S
Sbjct 982 SDGGDGVVSQ 991
>sp|Q63198|CNTN1_RAT Contactin-1 OS=Rattus norvegicus OX=10116
GN=Cntn1 PE=1 SV=2
Length=1021
Score = 228 bits (580), Expect = 8e-61, Method: Composition-based stats.
Identities = 76/383 (20%), Positives = 127/383 (33%), Gaps = 24/383 (6%)
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS--QIPPEDTASTRSSFTVQDLK 290
+ ++ + LTW+ S I KY IQ +T + W + P S DL
Sbjct 615 EDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMESAKAVDLI 674
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
P+ EY FR+ G G S S T P+ APS R + +
Sbjct 675 PWMEYEFRVVATNTLGTGEPSIPSN--RIKTDGAAPNVAPSDVGG----GGGTNRELTIT 728
Query 351 WKTLPPFEANGKILDYEVTL-----TRWKSHLQNYTVNATKL---TVNLTNDRYLATLTV 402
W L G Y V WK + + + +
Sbjct 729 WAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMTPSTAFQVKVKA 788
Query 403 RNLVGKSDAAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK-YILEWCV 459
N G +++ + A D + P + + V W E + + Y + +
Sbjct 789 FNNKGDGPYSLIAVINSAQDAPSEAPTEVGVKVLSSSEISVHWKHVLEKIVESYQIRYWA 848
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-SIKAYLKQAP 518
DK Q + NL Y I V + G G I+ + ++AP
Sbjct 849 GHDKEAAAHRVQVTS--QEYSARLENLLPDTQYFIEVGACNSAGCGPSSDVIETFTRKAP 906
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
PS+ P + + + ++ WD + + Y I YR ++ + S+H
Sbjct 907 PSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKILYRPDGQHDGKL--FSTHKHSI 964
Query 579 LSSLTSDTLYMVRMAAYTDEGGK 601
+ D Y+V + A++D G
Sbjct 965 EVPIPRDGEYVVEVRAHSDGGDG 987
Score = 124 bits (310), Expect = 1e-27, Method: Composition-based stats.
Identities = 54/394 (14%), Positives = 120/394 (30%), Gaps = 42/394 (11%)
Query 140 KKMRCEWDGGRETHLE-TNFTLKSEW-ATHKFADCKAK---RDTPTSCTVDYSTVYFVNI 194
+ W G + H + +T++++ + + D K + + ++
Sbjct 620 TSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMESAKAVDLIPWMEY 679
Query 195 EVWVEAENALGKV-TSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSV 252
E V A N LG S N PN P ++ + L +TW S +
Sbjct 680 EFRVVATNTLGTGEPSIPSNRIKTDGAAPNVAPSDVG--GGGGTNRELTITWAPLSREYH 737
Query 253 I--ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
Y + ++ D W ++ + + R + + P T + +++ G G +
Sbjct 738 YGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMTPSTAFQVKVKAFNNKGDGPY 797
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S A + +D PS+AP+ + + WK + + Y++
Sbjct 798 SL---IAVINSAQDAPSEAPTEVGV----KVLSSSEISVHWKHVLEK----IVESYQIRY 846
Query 371 TRWKSHLQ-------NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQ 422
+ +L L + +Y + N G ++ V+
Sbjct 847 WAGHDKEAAAHRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPSSDVIETFTRKAP 906
Query 423 ATHPVMDLKAFPKDNMLWVEWTTP-----RESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
+ P + + + + W +V Y + + + +
Sbjct 907 PSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKILYRPDGQHDGKLFSTHKHS--- 963
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
+ + Y++ V G G +K
Sbjct 964 ----IEVPIPRDGEYVVEVRAHSDGGDGVVSQVK 993
Score = 55.2 bits (131), Expect = 3e-06, Method: Composition-based stats.
Identities = 42/250 (17%), Positives = 76/250 (30%), Gaps = 18/250 (7%)
Query 67 WKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPP 126
WK T P + T T + +++ + I P
Sbjct 756 WKKVTVTNPDTGRYVHKDE----TMTPSTAFQVKVKAFNNKGDGPYSLIAVINSAQDAPS 811
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
E P + V ++ W E +E ++ ++ WA H + +
Sbjct 812 EAPTEVGVKVLSSSEISVHWKHVLEKIVE-SYQIRY-WAGHDKEAAAHRVQVTSQEYSAR 869
Query 187 STVYF--VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ V A N+ G S + K P+ P + + + S + +TW
Sbjct 870 LENLLPDTQYFIEVGACNSAGCGPSSDVIETFTRKAPPSQPPRI-ISSVRSGSRYI-ITW 927
Query 245 TN--PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
+ + Y I YR Q + ++ + S V + EYV +R
Sbjct 928 DHVVALSNESTVTGYKILYRPDG-----QHDGKLFSTHKHSIEVP-IPRDGEYVVEVRAH 981
Query 303 KEDGKGYWSD 312
+ G G S
Sbjct 982 SDGGDGVVSQ 991
>sp|Q28106|CNTN1_BOVIN Contactin-1 OS=Bos taurus OX=9913 GN=CNTN1
PE=2 SV=1
Length=1018
Score = 225 bits (574), Expect = 4e-60, Method: Composition-based stats.
Identities = 74/414 (18%), Positives = 135/414 (33%), Gaps = 24/414 (6%)
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS--QIPPEDTASTRSSFTVQDLK 290
+ ++ + LTW+ S I KY IQ +T + W + P + DL
Sbjct 613 EDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLI 672
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
P+ EY FR+ G G S S + T P+ APS R + +
Sbjct 673 PWMEYEFRVVATNTLGIGEPSIPSNK--IKTDGAAPNVAPSDVGG----GGGSNRELTIT 726
Query 351 WKTLPPFEANGKILDYEVTL-----TRWKSHLQNYTVNATKL---TVNLTNDRYLATLTV 402
W L Y V WK + + + +
Sbjct 727 WAPLSREYHYFNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMRPSTAFQVKVKA 786
Query 403 RNLVGKSDAAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK-YILEWCV 459
N G ++ + A D + P + + V W E + + Y + +
Sbjct 787 FNNKGDGPYSLTAVIHSAQDAPSEAPTAVGVKVLSSSEISVHWEHVVEKIVESYQIRYWA 846
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI-KAYLKQAP 518
DK Q + + NL Y + V + G G P + + + K+AP
Sbjct 847 SHDKEAAAHRVQV--ASQEYSARLENLLPDTQYFVEVRACNSAGCGPPSDMTETFTKKAP 904
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
PS+ P + + + ++ WD + + Y + YR ++ + S+H
Sbjct 905 PSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKLY--STHKHSI 962
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLT 632
+ D Y+V + A++D G + + + ++P +
Sbjct 963 EVPIPRDGEYVVEVRAHSDGGDGVVSQVKISGASILSPCLLGFLLPALGILVYL 1016
Score = 121 bits (304), Expect = 7e-27, Method: Composition-based stats.
Identities = 59/397 (15%), Positives = 127/397 (32%), Gaps = 48/397 (12%)
Query 140 KKMRCEWDGGRETHLE-TNFTLKSEW-ATHKFADCKAKR---DTPTSCTVDYSTVYFVNI 194
+ W G + H + +T++++ + + D K + + ++
Sbjct 618 TSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEY 677
Query 195 EVWVEAENALGKV-TSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSV 252
E V A N LG S N PN P ++ + L +TW S +
Sbjct 678 EFRVVATNTLGIGEPSIPSNKIKTDGAAPNVAPSDVG--GGGGSNRELTITWAPLSREYH 735
Query 253 II--LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
Y + ++ D W ++ + + R + ++P T + +++ G G +
Sbjct 736 YFNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMRPSTAFQVKVKAFNNKGDGPY 795
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL-DYEVT 369
S A + +D PS+AP+ + + W+ KI+ Y++
Sbjct 796 SL---TAVIHSAQDAPSEAPTAVGV----KVLSSSEISVHWE-----HVVEKIVESYQIR 843
Query 370 LTRWKSHLQN---------YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT-IPAC 419
W SH + + +L L + +Y + N G + +T
Sbjct 844 Y--WASHDKEAAAHRVQVASQEYSARLENLLPDTQYFVEVRACNSAGCGPPSDMTETFTK 901
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTP-----RESVKKYILEWCVLSDKAPCITDWQQED 474
+ P + + + + W +V Y + + +
Sbjct 902 KAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKL------- 954
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
+ H+ + + Y++ V G G +K
Sbjct 955 YSTHKHSIEVPIPRDGEYVVEVRAHSDGGDGVVSQVK 991
>sp|B0V2N1|PTPRS_MOUSE Receptor-type tyrosine-protein phosphatase
S OS=Mus musculus OX=10090 GN=Ptprs PE=1 SV=1
Length=1907
Score = 227 bits (579), Expect = 5e-60, Method: Composition-based stats.
Identities = 87/440 (20%), Positives = 165/440 (38%), Gaps = 42/440 (10%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A ++LG + + K P P V +E ++ + +TW + + Y I
Sbjct 300 AMSSLGVIEA---VAQITVKSLPKAPGTPVV--TENTATSITVTWDSG--NPDPVSYYVI 352
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+Y++K QI + T + +++ L P +EY + + G+G SE
Sbjct 353 EYKSKSQDGPYQIKEDIT---TTRYSIGGLSPNSEYEIWVSAVNSIGQG---PPSESVVT 406
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH--- 376
T E P+ AP + T+ + W+ P E NG I Y V T H
Sbjct 407 RTGEQAPASAPRNV----QARMLSATTMIVQWEE--PVEPNGLIRGYRVYYTMEPEHPVG 460
Query 377 -LQNYTVNATKLTV---NLTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLK 431
Q + V+ + LT L ++ Y + VG + + + P+
Sbjct 461 NWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRA 520
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
+ + + W+ PR+ ++++ +L + + + ++ +L +
Sbjct 521 EAKSETSIGLSWSAPRQES---VIKYELLFREGDRGREVGR-TFDPTTAFVVEDLKPNTE 576
Query 492 YLITVTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y + G G+ ++ QA PS P V+ + ++ W P + NG
Sbjct 577 YAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAILVSWRPPPPETHNG 636
Query 550 FIRNYTIFYRTIIGNETAV----NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ Y++ YR + + N+ + T+ L +L T Y V AYT+ G GPE
Sbjct 637 ALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVG--PGPE 694
Query 606 FTFTTPKFAQGEIEAIVVPV 625
+ P + + + P
Sbjct 695 SS---PVVVRTDEDVPSAPP 711
Score = 224 bits (570), Expect = 5e-59, Method: Composition-based stats.
Identities = 107/594 (18%), Positives = 189/594 (32%), Gaps = 56/594 (9%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
I P S + N CV Y+ W + E + R +T
Sbjct 236 ILPMSHEIMPGGNVNITCV-------AVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELT 288
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
+ TC ++ + + V IT+ S P+ P N + WD G
Sbjct 289 ---DVKDSANYTCVAMSSLGVIEAVAQITVKS--LPKAPGTPVVTENTATSITVTWDSGN 343
Query 151 ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-TS 209
++ + + + + K D T+ E+WV A N++G+ S
Sbjct 344 PD--PVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPS 401
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA--- 266
+ + + + P N+ + I++ W P + +I Y + Y +
Sbjct 402 ESVVTRTGEQAPASAPRNVQARMLSATTMIVQ--WEEPVEPNGLIRGYRVYYTMEPEHPV 459
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
W + +D+ T TV L Y R+ G G SD T + P
Sbjct 460 GNWQKHNVDDSLLT----TVGSLLEDETYTVRVLAFTSVGDGPLSD---PIQVKTQQGVP 512
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ--NYTVNA 384
+ + + + ++ L W ++ YE+ +
Sbjct 513 GQPMNLR-----AEAKSETSIGLSWSAPRQE----SVIKYELLFREGDRGREVGRTFDPT 563
Query 385 TKLTVN--LTNDRYLATLTVRNLVGKSDA-AVLTIPACDFQATHPVMDLKAFP-KDNMLW 440
T V N Y L R+ G AV+ + + P D+K + +
Sbjct 564 TAFVVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAPPQDVKCTSLRSTAIL 623
Query 441 VEWTTPR-----ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLIT 495
V W P ++ Y + + L + P + T L L + Y +T
Sbjct 624 VSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTT-QILLEALEKWTEYRVT 682
Query 496 VTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
GPG + + PS P V + + + W Q+G IR
Sbjct 683 AVAYTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRG 742
Query 554 YTIFYRTIIGNETAVNVD------SSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
Y + Y + G E + E +++L +T Y + +AAYT +G
Sbjct 743 YQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKGDG 796
Score = 223 bits (569), Expect = 6e-59, Method: Composition-based stats.
Identities = 93/513 (18%), Positives = 168/513 (33%), Gaps = 43/513 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRET-----HLETNFTLKSEWATHKFADCKAKRDTP 179
P P+N+ + M +W+ E +T++ E +
Sbjct 413 PASAPRNVQARMLSATTMIVQWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLL 472
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSS 238
T+ S + V V A ++G SD I V P P NL E S
Sbjct 473 TT---VGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGV-PGQPMNLRAEAKSETS- 527
Query 239 ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ L+W+ P +S ++KY + +R D T ++F V+DLKP TEY FR
Sbjct 528 -IGLSWSAPRQES--VIKYELLFREGDRGR----EVGRTFDPTTAFVVEDLKPNTEYAFR 580
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+ G G + + T + +PS P + + + W+ PP
Sbjct 581 LAARSPQGLGAF---TAVVRQRTLQAKPSAPPQDVK----CTSLRSTAILVSWRPPPPET 633
Query 359 ANGKILDYEVTLTRWKS------HLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSD 410
NG ++ Y V S + N T++ + Y T VG
Sbjct 634 HNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVAYTEVGPGP 693
Query 411 AAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTP-----RESVKKYILEW-CVLSD 462
+ + D + P + V W +P ++ Y + + +
Sbjct 694 ESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGA 753
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+A + + + NL Y ITV G G+ K + +
Sbjct 754 EARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGR 813
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
PT+ ++ + + W+ P D + Y + + + + + + +
Sbjct 814 PTLSVQQTPEGSLLARWEP-PADAAEDPVLGYRLQFGREDAAPATLELAAWERRF-AAPA 871
Query 583 TSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ 615
Y+ R+AA G + + P+ A
Sbjct 872 HKGATYVFRLAARGRAGLGEEAAAALSIPEDAP 904
Score = 199 bits (506), Expect = 5e-51, Method: Composition-based stats.
Identities = 98/656 (15%), Positives = 186/656 (28%), Gaps = 63/656 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGR-ETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P +P NL + W R E+ ++ + + + PT+
Sbjct 511 VPGQPMNLRAEAKSETSIGLSWSAPRQESVIKYELLFREGDRGREV----GRTFDPTTAF 566
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
V + A + G + + KP+ P V + S+ + ++
Sbjct 567 VVEDLKPNTEYAFRLAARSPQGLGAFTAVVRQRTLQAKPSAP-PQDVKCTSLRSTAILVS 625
Query 244 WTNPSIK--SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
W P + + ++ Y+++YR + + T + ++ L+ +TEY
Sbjct 626 WRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPPTTTQILLEALEKWTEYRVTAVA 685
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
E G G S T ED PS P + ++++W++ P +G
Sbjct 686 YTEVGPGPESS---PVVVRTDEDVPSAPPRKVE----AEALNATAIRVLWRSPTPGRQHG 738
Query 362 KILDYEVTLTRWKSHLQNYT----------VNATKLTVNLTNDRYLATLTVRNLVGKSDA 411
+I Y+V R + +T Y T+ + G
Sbjct 739 QIRGYQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKGDGAR 798
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
+ + + L W P ++ + +L + + +
Sbjct 799 SKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPADAAEDPVLGYRLQFGREDAAPATL 858
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV--RTKK 529
+ R + + Y+ + G G + + + P P +
Sbjct 859 ELAAWERRFAAPAH--KGATYVFRLAARGRAGLGEEAAAALSIPEDAPRGFPQILGAAGN 916
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-------TAVNVDSSHTEYTLSSL 582
V +L W +NG I YT+ R A + T TL L
Sbjct 917 VSAGSVLLRWLPPVPAERNGAIIKYTVSVREAGAPGPATETELAAAAQPGAETALTLRGL 976
Query 583 TSDTLYMVRMAAYTDEGGKD-GPEFTFTT------PKFAQGEIEAIV------------- 622
+T Y +R+ A+T G P + PK + ++
Sbjct 977 RPETAYELRVRAHTRRGPGPFSPPLRYRLARDPVSPKNFKVKMIMKTSVLLSWEFPDNYN 1036
Query 623 VPVCLAFLLTTLLGVLFCFNKRDLI----KKHIWPNVPDPSKSHIAQWSPHTPPRHNFNS 678
P L + + LI + V S + R FN
Sbjct 1037 SPTPYKIQYNGLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGLQQTVTARTAFNM 1096
Query 679 KDQMYSDGNFTDVS--VVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSS 732
S D +V + + P + + K G + GS
Sbjct 1097 LSGKPSVAPKPDNDGFIVVYLPDGQSPVTVQNYFIVMVPLRKSRG-GQFPVLLGSP 1151
Score = 158 bits (400), Expect = 4e-38, Method: Composition-based stats.
Identities = 82/509 (16%), Positives = 148/509 (29%), Gaps = 45/509 (9%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN---FTLKSEWATHKFADCKAKRDTP- 179
P P+++ C + W ++++ + D K + P
Sbjct 604 KPSAPPQDVKCTSLRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPDPKEVNNIPP 663
Query 180 -TSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELS 237
T+ + + + V A +G S + V PP V +
Sbjct 664 TTTQILLEALEKWTEYRVTAVAYTEVGPGPESSPVVVRTDEDVPSAPPR--KVEAEALNA 721
Query 238 SILKLTWTNPSIK--SVIILKYNIQY-RTKDASTWSQIPPEDT-ASTRSSFTVQDLKPFT 293
+ +++ W +P+ I Y + Y R + A +D + + +L+P T
Sbjct 722 TAIRVLWRSPTPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPET 781
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
Y + G G S + + P+ + P + R W+
Sbjct 782 AYSITVAAYTMKGDGARSKP----KVVVTKGAVLGRPTLSVQQTPEGSLLAR-----WEP 832
Query 354 LPPFEANGKILDYEVTLTRWKSH--LQNYTVNATKLTVNLTNDR-YLATLTVR--NLVGK 408
P A +L Y + R + + Y+ L R +G+
Sbjct 833 -PADAAEDPVLGYRLQFGREDAAPATLELAAWERRFAAPAHKGATYVFRLAARGRAGLGE 891
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP-RESVKKYILEWCVLSDKA--- 464
AA L+IP + ++ + + W P I+++ V +A
Sbjct 892 EAAAALSIPEDAPRGFPQILGAAGNVSAGSVLLRWLPPVPAERNGAIIKYTVSVREAGAP 951
Query 465 ---PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
L Y + V GPG Y P
Sbjct 952 GPATETELAAAAQPGAETALTLRGLRPETAYELRVRAHTRRGPGPFSPPLRYRLARDPVS 1011
Query 522 GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS 581
+ K + K +L W+ D N Y I Y N ++VD T+ ++
Sbjct 1012 PKNFKVKMIMKTSVLLSWEF--PDNYNSP-TPYKIQY-----NGLTLDVDGRTTKKLITH 1063
Query 582 LTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
L T Y + T+ G G T
Sbjct 1064 LKPHTFYNFVL---TNRGSSLGGLQQTVT 1089
Score = 141 bits (355), Expect = 1e-32, Method: Composition-based stats.
Identities = 89/462 (19%), Positives = 161/462 (35%), Gaps = 86/462 (19%)
Query 200 AENALGKVTSD-HINFDPVYKVKPNPP-----HNLSVINSEELSSIL---------KLTW 244
A+N++G++T + ++ P P L V+ +++L ++TW
Sbjct 109 AQNSVGEITIHAKLTVLREDQLPPGFPNIDMGPQLKVVERTRTATMLCAASGNPDPEITW 168
Query 245 ------TNPSIKSVIILKYN---IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+PS + I + +Q + + + + T S ++ P Y
Sbjct 169 FKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS----SPANLY 224
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
R+R AP F V +
Sbjct 225 -VRVR--------------------------RVAPRFSILPMSHEIMPGGNVNIT----- 252
Query 356 PFEANGKILDYEVTLTRWK--SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK-SDAA 412
A G + Y + + + + V L + D T + +G A
Sbjct 253 -CVAVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVA 311
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQ 471
+T+ + PV+ + V W + + V Y++E+ S P +Q
Sbjct 312 QITVKSLPKAPGTPVVT---ENTATSITVTWDSGNPDPVSYYVIEYKSKSQDGP----YQ 364
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-ESIKAYLKQAPPSKGP-TVRTKK 529
++ Y G L+ + Y I V+ V + G G P ES+ + P+ P V+ +
Sbjct 365 IKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARM 424
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFY----RTIIGNETAVNVDSSHTEYTLSSLTSD 585
+ +++W++ NG IR Y ++Y +GN NVD S T+ SL D
Sbjct 425 LSATTMIVQWEE--PVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLT-TVGSLLED 481
Query 586 TLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
Y VR+ A+T G DGP + P + + P+ L
Sbjct 482 ETYTVRVLAFTSVG--DGP---LSDPIQVKTQQGVPGQPMNL 518
Score = 103 bits (256), Expect = 5e-21, Method: Composition-based stats.
Identities = 85/545 (16%), Positives = 144/545 (26%), Gaps = 62/545 (11%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P P + + + + + N+ Q + + +T
Sbjct 628 PPPPETHNGALVGYSVRYRPLGSEDP--DPKEV----NNIPPTTTQILL----EALEKWT 677
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD---GG 149
+ + T + G V + +P P+ + +R W G
Sbjct 678 EYRVTAVAYT--EVGPGPESSPVV-VRTDEDVPSAPPRKVEAEALNATAIRVLWRSPTPG 734
Query 150 RETH----LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
R+ + ++ K V + + V A G
Sbjct 735 RQHGQIRGYQVHYVRMEGAEARGPPRIKDIMLADAQEMVITNLQPETAYSITVAAYTMKG 794
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTK 264
P LSV + E S L W P+ +L Y +Q+ +
Sbjct 795 DGARSKPKVVVTKGAVLGRPT-LSVQQTPEGS--LLARWEPPADAAEDPVLGYRLQFGRE 851
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
DA+ + A+ F YVFR+ G G A+ ED
Sbjct 852 DAAP----ATLELAAWERRFAAP-AHKGATYVFRLAARGRAGLGEE----AAAALSIPED 902
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH-------- 376
P P + +V L W P E NG I+ Y V++ +
Sbjct 903 APRGFPQILGA---AGNVSAGSVLLRWLPPVPAERNGAIIKYTVSVREAGAPGPATETEL 959
Query 377 ---LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF 433
Q A L Y + G + P
Sbjct 960 AAAAQPGAETALTLRGLRPETAYELRVRAHTRRGPGPFSPPLRYRLARDPVSPKNFKVKM 1019
Query 434 PKDNMLWVEWTTPRE--SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
+ + W P S Y +++ L+ DG + L +L
Sbjct 1020 IMKTSVLLSWEFPDNYNSPTPYKIQYNGLTLD---------VDGRTTK-KLITHLKPHTF 1069
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
Y +T + G +++ A S P+V K V+ LP +
Sbjct 1070 YNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSVAPKPDNDGFIVV---YLPDGQSPVTV 1126
Query 552 RNYTI 556
+NY I
Sbjct 1127 QNYFI 1131
>sp|P16621|LAR_DROME Tyrosine-protein phosphatase Lar OS=Drosophila
melanogaster OX=7227 GN=Lar PE=1 SV=2
Length=2029
Score = 227 bits (577), Expect = 9e-60, Method: Composition-based stats.
Identities = 118/650 (18%), Positives = 198/650 (30%), Gaps = 94/650 (14%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P + V+++ C I W N + R + F
Sbjct 146 PGTRVIEVGHTVLMTC-------KAIGNPTPNIYWIKNQTKVDMSN----PRYSLKDGFL 194
Query 93 DIASLNIQLTCNILTF--------GQLEQNVYGITIIS----GLPPEKPK--------NL 132
I + + N+Y PPE NL
Sbjct 195 QIENSREEDQGKYECVAENSMGTEHSKATNLYVKVRRVPPTFSRPPETISEVMLGSNLNL 254
Query 133 SCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV 192
SCI +W G E N + + + +C
Sbjct 255 SCIAVGSPMPHVKWMKGSEDLTPEN---EMPIGRNVLQLINIQESANYTCI--------- 302
Query 193 NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV 252
A + LG++ S + KV+ P V SE ++ ++L W+ +
Sbjct 303 -------AASTLGQIDSVSV-----VKVQSLPTAPTDVQISEVTATSVRLEWSYKGPED- 349
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ Y IQY+ K+A +Q E + + V+ L P+TEY F + + G+G
Sbjct 350 -LQYYVIQYKPKNA---NQAFSEISGIITMYYVVRALSPYTEYEFYVIAVNNIGRG---P 402
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT- 371
S A+ T E + AP T T+ + W+ PP NG++ Y+V T
Sbjct 403 PSAPATCTTGETKMESAPRNV----QVRTLSSSTMVITWE--PPETPNGQVTGYKVYYTT 456
Query 372 ---RWKSHLQNYTVNATKLTVNLTNDR---YLATLTVRNLVGKSDAAVLTIPACDFQATH 425
+ ++ + V+ ++LT Y + +G +
Sbjct 457 NSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPS 516
Query 426 PVMDLKAFP-KDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
+ +A + + ++WT P E++ Y L W + Y
Sbjct 517 QPSNFRATDIGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHKRISNSE-----AY 571
Query 482 LRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEW 539
L Y I + G G+ I KQ P P + L W
Sbjct 572 TLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATSSTTISLSW 631
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETA-VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
PV+ NG I Y +F+ + + + + T L L T Y + + A T
Sbjct 632 LPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTSV 691
Query 599 GGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIK 648
G DGP P + + + P + + K L K
Sbjct 692 G--DGPRSH---PIILRTQEDVPGDPQDVKATPLNSTSIHVS-WKPPLEK 735
Score = 207 bits (526), Expect = 2e-53, Method: Composition-based stats.
Identities = 95/586 (16%), Positives = 181/586 (31%), Gaps = 48/586 (8%)
Query 66 VWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGL- 124
V+ T + P+ + S +T + + T + + + +
Sbjct 452 VYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQ 511
Query 125 --PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSC 182
P +P N + +W + TH N + +A+ + S
Sbjct 512 QGVPSQPSNFRATDIGETAVTLQWT--KPTHSSENIVHYELYWNDTYANQAHHKRISNSE 569
Query 183 TVDYSTVY-FVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
+Y +W+ A + G+ T+ I V PP N++ I + S+ +
Sbjct 570 AYTLDGLYPDTLYYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIAT--SSTTI 627
Query 241 KLTWTNP--SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
L+W P + I+ Y + + +S + +LK +TEY
Sbjct 628 SLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTM---TLNMTSIVLDELKRWTEYKIW 684
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+ G G S T ED P + ++ + WK +
Sbjct 685 VLAGTSVGDG---PRSHPIILRTQEDVPGDPQDVK-----ATPLNSTSIHVSWKPPLEKD 736
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNATKL----------TVNLTNDRYLATLTVRNLVGK 408
NG I Y + + + + K T + +Y + G
Sbjct 737 RNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRKGD 796
Query 409 SD-AAVLTIPACDFQATHPVMDLKAFPKDN--MLWVEWTTPR---ESVKKYILEWCVLSD 462
D +A + + P + LK ++ + +EW P ++ Y L W V
Sbjct 797 GDRSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGELRGYRLRWGVKDQ 856
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+ G NL Y V G G + P
Sbjct 857 ----ALKEEMLSGPQMTKKRFDNLERGVEYEFRVAGSNHIGIGQETVKIFQTPEGTPGGP 912
Query 523 P-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS 581
P + + + + WD + +NG I Y + + I + + + + ++
Sbjct 913 PSNITIRFQTPDVLCVTWDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRKAVFTN 972
Query 582 LTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
L +T Y+ R+ AYT +G F+ + E + P+ L
Sbjct 973 LEENTEYIFRVRAYTKQGAGP-----FSDKLIVETERDMGRAPMSL 1013
Score = 158 bits (399), Expect = 5e-38, Method: Composition-based stats.
Identities = 105/694 (15%), Positives = 198/694 (29%), Gaps = 58/694 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRET---HLETNFTLKSEW---ATHKFADCKAKRDT 178
P P+++ + W E + + + ++ F + K D
Sbjct 708 VPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEGKGFLNEPFKFDV 767
Query 179 PTSCTVDYS-TVYFVNIEVWVEAENALGKV-TSDHINFDPVYKVKPNPPHNLSVINSEEL 236
+ + + + V A G S I V P +L ++ E +
Sbjct 768 VDTLEFNVTGLQPDTKYSIQVAALTRKGDGDRSAAIVVKTPGGVPVRPTVSLKIMEREPI 827
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
S ++L W P+ + Y +++ KD + ++ + + +L+ EY
Sbjct 828 VS-IELEWERPAQTYGELRGYRLRWGVKDQALKEEML---SGPQMTKKRFDNLERGVEYE 883
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
FR+ G G T E P PS Q + + W
Sbjct 884 FRVAGSNHIGIGQE----TVKIFQTPEGTPGGPPSNITI----RFQTPDVLCVTWDPPTR 935
Query 357 FEANGKILDYEVTLTRWKSHLQNYTVNAT----KLTVNLTNDRYLATLTVRNLVGKSDAA 412
NG I Y+V + H N T T N Y+ + G +
Sbjct 936 EHRNGIITRYDVQFHKKIDHGLGSERNMTLRKAVFTNLEENTEYIFRVRAYTKQGAGPFS 995
Query 413 VLTIPACDFQATHPVMDLKAFPKDNML-WVEWTTPRESVKKYILEWCVLSDKA--PCITD 469
I + M L+A + W + +L + + + D
Sbjct 996 DKLIVETERDMGRAPMSLQAEATSEQTAEIWWEPVT--SRGKLLGYKIFYTMTAVEDLDD 1053
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-SPESIKAYLK-QAPPSKGPTVRT 527
WQ + + + NL + Y + + + +G G E + +K + P +R
Sbjct 1054 WQTKTVGLTESADLVNLEKFAQYAVAIAARFKNGLGRLSEKVTVRIKPEDVPL---NLRA 1110
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-------------RTIIGNETAVNVDSSH 574
V + L W NY I + +T I + + +
Sbjct 1111 HDVSTHSMTLSWSPPIRLTP----VNYKISFDAMKVFVDSQGFSQTQIVPKREIILKHYV 1166
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTL 634
+T++ L+ T Y V ++A + P T + A + +V P +
Sbjct 1167 KTHTINELSPFTTYNVNVSAIPSDYSYRPPTKITVTTQMAAPQP--MVKPDFYGVVNGEE 1224
Query 635 LGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVV 694
+ V+ + + V P P + N ++
Sbjct 1225 ILVILPQASEEYGPISHYYLVVVPEDKSNLHKIPDQFLTDDLLPGRNKPERPNAPYIA-- 1282
Query 695 EIEANDKKPFPEDLKSLD---LFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQ 751
PF L S D F K+ E + + + +SS +E
Sbjct 1283 AKFPQRSIPFTFHLGSGDDYHNFTNRKLEREKRYRIFVRAVVDTPQKHLYTSSPFSEFLS 1342
Query 752 NTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQP 785
H + +V +P
Sbjct 1343 LDMREAPPGERPHRPDPNWPAEPEVSVNRNKDEP 1376
Score = 127 bits (319), Expect = 2e-28, Method: Composition-based stats.
Identities = 95/570 (17%), Positives = 188/570 (33%), Gaps = 70/570 (12%)
Query 51 KEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT-FTDIASLNIQLTCNILTFG 109
+ + +H++A + + F ++ +++ +VT +IQ+
Sbjct 737 RNGIIRGYHIHAQELRDEGKGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRKGD 796
Query 110 QLEQNVYGITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETN-FTLKSEWATH 167
+ G+P +L + E + EW+ +T+ E + L+
Sbjct 797 GDRSAAIVVKTPGGVPVRPTVSLKIMEREPIVSIELEWERPAQTYGELRGYRLRWGVKDQ 856
Query 168 KFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHN 227
+ T D + V E V N +G F PP N
Sbjct 857 ALKEEMLSGPQMTKKRFD-NLERGVEYEFRVAGSNHIGIGQETVKIFQTPEGTPGGPPSN 915
Query 228 LSVINSEELSSILKLTWTNP--SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
+++ + +L +TW P ++ II +Y++Q+ K + T
Sbjct 916 ITIRF--QTPDVLCVTWDPPTREHRNGIITRYDVQFHKKID----HGLGSERNMTLRKAV 969
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
+L+ TEY+FR+R + G G +SD + P + +
Sbjct 970 FTNLEENTEYIFRVRAYTKQGAGPFSDKLIVETERDMGRAPMSL--------QAEATSEQ 1021
Query 346 TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR---------- 395
T ++ W+ + + GK+L Y++ T +++ TK TV LT
Sbjct 1022 TAEIWWEPV---TSRGKLLGYKIFYTMTA--VEDLDDWQTK-TVGLTESADLVNLEKFAQ 1075
Query 396 YLATLTVR--NLVGK-SDAAVLTIPACDFQATHPVMDLKAFPKDN-MLWVEWTTPRESVK 451
Y + R N +G+ S+ + I D ++L+A + + W+ P
Sbjct 1076 YAVAIAARFKNGLGRLSEKVTVRIKPEDV-----PLNLRAHDVSTHSMTLSWSPPIRLTP 1130
Query 452 KYILEWCVLSDKAPCITDWQQEDGTV------------HRTYLRGNLAESKCYLITVTPV 499
+ + + D D Q T +T+ L+ Y + V+ +
Sbjct 1131 ---VNYKISFDAMKVFVDSQGFSQTQIVPKREIILKHYVKTHTINELSPFTTYNVNVSAI 1187
Query 500 YAD-GPGSPESIKAYLKQAPPSKG--PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
+D P I + A P P G+ V+ + G I +Y +
Sbjct 1188 PSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGEEILVI---LPQASEEYGPISHYYL 1244
Query 557 FYRTIIGNETAVNVDSSHTEYTLSSLTSDT 586
++ E N+ ++ L
Sbjct 1245 ----VVVPEDKSNLHKIPDQFLTDDLLPGR 1270
>sp|Q4VA61|DSCL1_MOUSE Cell adhesion molecule DSCAML1 OS=Mus musculus
OX=10090 GN=Dscaml1 PE=1 SV=2
Length=2053
Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats.
Identities = 102/519 (20%), Positives = 183/519 (35%), Gaps = 44/519 (8%)
Query 129 PKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYST 188
PK L+C + + W+ G +T ++ + ++ AT D +
Sbjct 805 PKELNCTARGERPIIIRWEKG-DTVIDPDRVMRYAIATKDNGDEVVSTLKLKP-ADRGDS 862
Query 189 VYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
V+F A N+ G+ D + P+PP + E + + L WT
Sbjct 863 VFFSCH-----AINSYGE---DRGLIQLTVQEPPDPPE---LEIREVKARSMNLRWTQRF 911
Query 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
+ II ++I+Y+ K S + + + T + + DL P + Y R+ + G+
Sbjct 912 DGNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGR- 970
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
S+ S+E + T E P P + P +Q ++Q+ WK NG I Y++
Sbjct 971 --SEPSKELTISTEEAAPDGPP-MDVTLQPVTSQ---SIQVTWKAPKKELQNGVIRGYQI 1024
Query 369 TLTRWKSHLQ--------NYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAA--VLTI 416
T ++ T++ +Y + N G ++ +
Sbjct 1025 GYRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINAT 1084
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL-EWCVLSDKAPCITDW---QQ 472
D + P ++ + W+ P S +L + V+ +W Q
Sbjct 1085 TLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQN 1144
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI-KAYLKQAPPSKGPTVRTKKVG 531
T R LRG + + Y + V G G S+ K+ P ++
Sbjct 1145 VTTTRERVELRG-MEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSS 1203
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYTLSSLTSDTLY 588
+ V+ W LP NG IR YTIF + + + Y ++ L Y
Sbjct 1204 ASSVVVSW--LPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQY 1261
Query 589 MVRMAAYTDEGGKDGPEFTFTTPKF-AQGEIEAIVVPVC 626
++ +AA T G + E P A +I + V
Sbjct 1262 LLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVT 1300
Score = 119 bits (299), Expect = 5e-26, Method: Composition-based stats.
Identities = 89/543 (16%), Positives = 171/543 (31%), Gaps = 58/543 (11%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-----TNF 158
N G + T+ +P + P+N+ + W + L
Sbjct 1070 NRAGTGPSSSEINATTLE-DVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRV 1128
Query 159 TLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVY 218
S + ++ + + T + F N V V A G + +
Sbjct 1129 IFWSLYVDGEWGEMQNVTTTRERVELRGME-KFTNYSVQVLAYTQAGDGVRSSVLYIQTK 1187
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
+ P PP + + S S ++ W P+ + +I KY I + + + E T+
Sbjct 1188 EDVPGPPAGIKAVPSSASSVVVS--WLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYE-TS 1244
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID- 337
+ + + L +Y+ + + G+G + SE+ + P+K SF +
Sbjct 1245 PEQLFYRIAHLNRGQQYLLWVAAVTSAGRG---NSSEKVTIEPAGKAPAKIISFGGTVTT 1301
Query 338 --------PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV 389
P ++ G + W A + ++ H +T L
Sbjct 1302 PWMKDVRLPCNSVGDPAPAVKWTKDSEDSA--------IPVS-LDGHRLIHTNGTLLLRA 1352
Query 390 NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE- 448
D T T N G ++ P + + + + + W
Sbjct 1353 VKAEDSGYYTCTATNTGGF--DTIIVNLLVQVPPDQPRLTVSKTSASS-ITLTWIPGDNG 1409
Query 449 --SVKKYILEWCVLSDKAPCITDWQQE-DGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
S++ ++L++ V + + W+ + R++ +L Y + + + G G
Sbjct 1410 GSSIRGFVLQYSVDNSEE-----WKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSG 1464
Query 506 S-PESIKAYL--KQAPPSKGPTV-RTKKVGKNEAVLE-WDQLPVDVQNG--FIRNYTIFY 558
E I+A ++ SK + L+ W NG I + Y
Sbjct 1465 RISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGW-------NNGGCPITAIVLEY 1517
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEI 618
R +S TE L+ L T Y +RM A G + F T + I
Sbjct 1518 RPKGTWAWQGVRANSSTEVFLTELREATWYELRMRACNSAGCGNET-AQFATLDYDGSTI 1576
Query 619 EAI 621
I
Sbjct 1577 PPI 1579
Score = 74.5 bits (181), Expect = 4e-12, Method: Composition-based stats.
Identities = 46/243 (19%), Positives = 75/243 (31%), Gaps = 23/243 (9%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A N G D I + + +V P+ P L+V + +S + LTW I +
Sbjct 1364 TATNTGG---FDTIIVNLLVQVPPDQPR-LTVSKT--SASSITLTWIPGDNGGSSIRGFV 1417
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+QY ++ W + +S+ SF + LK T Y ++ G G SE
Sbjct 1418 LQYSVDNSEEWKDV---FISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRI---SEIIE 1471
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
T+ PS + + T +Q W I + +
Sbjct 1472 AKTHGREPSFSKDQHLFTHINSTHARLNLQ-GW-----NNGGCPITAIVLEYRPKGTWAW 1525
Query 379 NYTVNATKLTVNLTNDR----YLATLTVRNLVGKSDAAVLTIPAC-DFQATHPVMDLKAF 433
+ V LT R Y + N G + D P+ +
Sbjct 1526 QGVRANSSTEVFLTELREATWYELRMRACNSAGCGNETAQFATLDYDGSTIPPIKSAQGE 1585
Query 434 PKD 436
D
Sbjct 1586 GDD 1588
>sp|Q8TD84|DSCL1_HUMAN Cell adhesion molecule DSCAML1 OS=Homo
sapiens OX=9606 GN=DSCAML1 PE=1 SV=2
Length=2053
Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats.
Identities = 101/518 (19%), Positives = 182/518 (35%), Gaps = 44/518 (8%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
K L+C + + W+ G +T ++ + ++ AT D +V
Sbjct 806 KELNCTARGERPIIIRWEKG-DTVIDPDRVMRYAIATKDNGDEVVSTLKLKP-ADRGDSV 863
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+F A N+ G+ D + P+PP + E + + L WT
Sbjct 864 FFSCH-----AINSYGE---DRGLIQLTVQEPPDPPE---LEIREVKARSMNLRWTQRFD 912
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ II ++I+Y+ K S + + + T + + DL P + Y R+ + G+
Sbjct 913 GNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGR-- 970
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
S+ S+E + T E P P + P +Q ++Q+ WK NG I Y++
Sbjct 971 -SEPSKELTISTEEAAPDGPP-MDVTLQPVTSQ---SIQVTWKAPKKELQNGVIRGYQIG 1025
Query 370 LTRWKSHLQ--------NYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAA--VLTIP 417
T ++ T++ +Y + N G ++ +
Sbjct 1026 YRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATT 1085
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL-EWCVLSDKAPCITDW---QQE 473
D + P ++ + W+ P S +L + V+ +W Q
Sbjct 1086 LEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNI 1145
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI-KAYLKQAPPSKGPTVRTKKVGK 532
T R LRG + + Y + V G G S+ K+ P ++
Sbjct 1146 TTTRERVELRG-MEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSA 1204
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYTLSSLTSDTLYM 589
+ V+ W LP NG IR YTIF + + + Y ++ L Y+
Sbjct 1205 SSVVVSW--LPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYL 1262
Query 590 VRMAAYTDEGGKDGPEFTFTTPKF-AQGEIEAIVVPVC 626
+ +AA T G + E P A +I + V
Sbjct 1263 LWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVT 1300
Score = 155 bits (392), Expect = 4e-37, Method: Composition-based stats.
Identities = 94/563 (17%), Positives = 177/563 (31%), Gaps = 52/563 (9%)
Query 71 HFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPK 130
F + A+ V + +I++ I+ P P
Sbjct 932 DFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPM 991
Query 131 NLSCIVNEGKKMRCEWDG-------GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
+++ + ++ W G + + S + +++ + K +
Sbjct 992 DVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVY 1051
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDH-INFDPVYKVKPNPPHNLSVINSEELSSILKL 242
+ F V V+A N G S IN + V PP N+ ++ S + +
Sbjct 1052 TLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSI--TSDVAVI 1109
Query 243 TWTNPSIK--SVIILKYNIQYRTKD-ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+W+ P + ++ Y + + + W ++ ++ +TR ++ ++ FT Y ++
Sbjct 1110 SWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEM--QNITTTRERVELRGMEKFTNYSVQV 1167
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
+ G G S T ED P + + W LPP +
Sbjct 1168 LAYTQAGDGV---RSSVLYIQTKEDVPGPPAGIKAVPSSASSVVV-----SW--LPPTKP 1217
Query 360 NGKILDYEVTLTRWKSHLQNYTVNATK-------LTVNLTNDRYLATLTVRNLVGKSDAA 412
NG I Y + + S + T + +YL + G+ +++
Sbjct 1218 NGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSS 1277
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI------LEWCVLSDKA-- 464
+A ++ + W + ++W S+ +
Sbjct 1278 EKVTIEPAGKAPAKIISF-----GGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAI 1332
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
P D + T LR AE Y A G ++I L P P
Sbjct 1333 PVSMDGHRLIHTNGTLLLRAVKAEDSGY----YTCTATNTGGFDTIIVNLLVQVPPDQPR 1388
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLT 583
+ K + L W +P D IR + + Y E V + SS + L SL
Sbjct 1389 LTVSKTSASSITLTW--IPGDNGGSSIRGFVLQYSVDNSEEWKDVFISSSERSFKLDSLK 1446
Query 584 SDTLYMVRMAAYTDEGGKDGPEF 606
T Y V++AA G E
Sbjct 1447 CGTWYKVKLAAKNSVGSGRISEI 1469
Score = 118 bits (296), Expect = 1e-25, Method: Composition-based stats.
Identities = 88/543 (16%), Positives = 170/543 (31%), Gaps = 58/543 (11%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-----TNF 158
N G + T+ +P + P+N+ + W + L
Sbjct 1070 NRAGTGPSSSEINATTLE-DVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRV 1128
Query 159 TLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVY 218
S + ++ + + T + F N V V A G + +
Sbjct 1129 IFWSLYVDGEWGEMQNITTTRERVELRGME-KFTNYSVQVLAYTQAGDGVRSSVLYIQTK 1187
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
+ P PP + + S S ++ W P+ + +I KY I + + + E T+
Sbjct 1188 EDVPGPPAGIKAVPSSASSVVVS--WLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYE-TS 1244
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID- 337
+ + + L +Y+ + + G+G + SE+ + P+K SF +
Sbjct 1245 PEQLFYRIAHLNRGQQYLLWVAAVTSAGRG---NSSEKVTIEPAGKAPAKIISFGGTVTT 1301
Query 338 --------PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV 389
P ++ G + W A + ++ H +T L
Sbjct 1302 PWMKDVRLPCNSVGDPAPAVKWTKDSEDSA--------IPVSM-DGHRLIHTNGTLLLRA 1352
Query 390 NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE- 448
D T T N G ++ P + + + + + W
Sbjct 1353 VKAEDSGYYTCTATNTGGF--DTIIVNLLVQVPPDQPRLTVSKTSASS-ITLTWIPGDNG 1409
Query 449 --SVKKYILEWCVLSDKAPCITDWQQE-DGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
S++ ++L++ V + + W+ + R++ +L Y + + + G G
Sbjct 1410 GSSIRGFVLQYSVDNSEE-----WKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSG 1464
Query 506 S-PESIKAYL--KQAPPSKGPTV-RTKKVGKNEAVLE-WDQLPVDVQNG--FIRNYTIFY 558
E I+A ++ SK + L+ W NG I + Y
Sbjct 1465 RISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGW-------NNGGCPITAIVLEY 1517
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEI 618
R +S E L+ L T Y +RM A G + F T + I
Sbjct 1518 RPKGTWAWQGLRANSSGEVFLTELREATWYELRMRACNSAGCGNET-AQFATLDYDGSTI 1576
Query 619 EAI 621
I
Sbjct 1577 PPI 1579
Score = 73.0 bits (177), Expect = 1e-11, Method: Composition-based stats.
Identities = 46/243 (19%), Positives = 75/243 (31%), Gaps = 23/243 (9%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A N G D I + + +V P+ P L+V + +S + LTW I +
Sbjct 1364 TATNTGG---FDTIIVNLLVQVPPDQPR-LTVSKT--SASSITLTWIPGDNGGSSIRGFV 1417
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+QY ++ W + +S+ SF + LK T Y ++ G G SE
Sbjct 1418 LQYSVDNSEEWKDV---FISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRI---SEIIE 1471
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
T+ PS + + T +Q W I + +
Sbjct 1472 AKTHGREPSFSKDQHLFTHINSTHARLNLQ-GW-----NNGGCPITAIVLEYRPKGTWAW 1525
Query 379 NYTVNATKLTVNLTNDR----YLATLTVRNLVGKSDAAVLTIPAC-DFQATHPVMDLKAF 433
+ V LT R Y + N G + D P+ +
Sbjct 1526 QGLRANSSGEVFLTELREATWYELRMRACNSAGCGNETAQFATLDYDGSTIPPIKSAQGE 1585
Query 434 PKD 436
D
Sbjct 1586 GDD 1588
>sp|P35331|NRCAM_CHICK Neuronal cell adhesion molecule OS=Gallus
gallus OX=9031 PE=1 SV=1
Length=1284
Score = 221 bits (562), Expect = 4e-58, Method: Composition-based stats.
Identities = 97/472 (21%), Positives = 165/472 (35%), Gaps = 55/472 (12%)
Query 168 KFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHN 227
+ K D +C V+ + V A L V + + PNPP +
Sbjct 578 TIMNVTDKDDGTYTCIVNTTLDS-------VSASAVLTVVAAPPTPAIIYAR--PNPPLD 628
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
L + + +L ++L+W + I + I+Y +D + T S TVQ
Sbjct 629 LEL--TGQLERSIELSWVPGEENNSPITNFVIEY--EDGLHEPGVWHYQTEVPGSHTTVQ 684
Query 288 -DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
L P+ Y FR+ + E G+ S+ SE+ +T P + PS I
Sbjct 685 LKLSPYVNYSFRVIAVNEIGRSQPSEPSEQ--YLTKSANPDENPSNVQGI----GSEPDN 738
Query 347 VQLVWKTLPPFEANGKILDYEVTLT------RWKS----HLQNYTVNATKLTVNLTNDRY 396
+ + W++L F++NG L Y+V+ W S ++ Y V+ T V Y
Sbjct 739 LVITWESLKGFQSNGPGLQYKVSWRQKDVDDEWTSVVVANVSKYIVSGTPTFV-----PY 793
Query 397 LATLTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT-PRESVKKY 453
+ N +G + V+ D P + V W P +SV+ +
Sbjct 794 EIKVQALNDLGYAPEPSEVIGHSGEDLPMVAPGNVQVHVINSTLAKVHWDPVPLKSVRGH 853
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN--------LAESKCYLITVTPVYADGPG 505
+ + V K ++ + RGN L Y + V V G G
Sbjct 854 LQGYKVYYWKVQSLSRRSKRHVEKKILTFRGNKTFGMLPGLEPYSSYKLNVRVVNGKGEG 913
Query 506 SPESIKAY-LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI--- 561
K + + PS ++ + LEW NG + +Y + ++ I
Sbjct 914 PASPDKVFKTPEGVPSPPSFLKITNPTLDSLTLEWGS--PTHPNGVLTSYILKFQPINNT 971
Query 562 --IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTT 610
+G + + ++ + L +L T Y A T G G E T
Sbjct 972 HELGPLVEIRIPANESSLILKNLNYSTRYKFYFNAQTSVGSGSQITEEAVTI 1023
Score = 173 bits (439), Expect = 5e-43, Method: Composition-based stats.
Identities = 134/729 (18%), Positives = 244/729 (33%), Gaps = 101/729 (14%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P+ V+Q + + CV+K V +W ++ +P ++ ++ + ++T
Sbjct 528 PQYKVIQRSAQASFECVIKHDPTLIPTV-----IWLKDNNELPDDERFLVGK--DNLTIM 580
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEG----------KKM 142
++ + I+ + + + PP P + N + +
Sbjct 581 NVTDKDDGTYTCIVNTTLDSVSASAVLTVVAAPP-TPAIIYARPNPPLDLELTGQLERSI 639
Query 143 RCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTS-CTVDYSTVYFVNIEVWVEA 200
W G E + TNF ++ E H+ + + P S TV +VN V A
Sbjct 640 ELSWVPGEENNSPITNFVIEYEDGLHEPGVWHYQTEVPGSHTTVQLKLSPYVNYSFRVIA 699
Query 201 ENALGKV-TSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWT--NPSIKSVIILK 256
N +G+ S+ P+ P N+ I SE L +TW + L+
Sbjct 700 VNEIGRSQPSEPSEQYLTKSANPDENPSNVQGIGSE--PDNLVITWESLKGFQSNGPGLQ 757
Query 257 YNIQYRTKD-ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y + +R KD W+ + + + + V F Y +++ + + G + SE
Sbjct 758 YKVSWRQKDVDDEWTSVVVANVSK----YIVSGTPTFVPYEIKVQALNDLGYAP--EPSE 811
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
G + ED P AP H ++ W +P G + Y+V + +S
Sbjct 812 VI-GHSGEDLPMVAPGNV----QVHVINSTLAKVHWDPVPLKSVRGHLQGYKVYYWKVQS 866
Query 376 HLQNYTVNATK-------------LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
+ + K L Y + V N G+ A+ +
Sbjct 867 LSRRSKRHVEKKILTFRGNKTFGMLPGLEPYSSYKLNVRVVNGKGEGPASPDKVFKTPEG 926
Query 423 ATHPVMDLKAF-PKDNMLWVEW---TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
P LK P + L +EW T P + YIL++ +++ +
Sbjct 927 VPSPPSFLKITNPTLDSLTLEWGSPTHPNGVLTSYILKFQPINNTHELGPLVEIRIPANE 986
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL--KQA---PPSKG--------PTV 525
+ + NL S Y + G GS + +A +A P+ G P +
Sbjct 987 SSLILKNLNYSTRYKFYFNAQTSVGSGSQITEEAVTIMDEAGILRPAVGAGKVQPLYPRI 1046
Query 526 R--TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET--AVNVDSSHTEYTLSS 581
R T + A + W+ D N + + Y E V+ S + + L
Sbjct 1047 RNVTTAAAETYANISWEYEGPDHAN-----FYVEYGVAGSKEDWKKEIVNGSRSFFVLKG 1101
Query 582 LTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTT----LLGV 637
LT T Y VR+ A G + + T P A +++ + + L+ +
Sbjct 1102 LTPGTAYKVRVGAEGLSGFRSSEDLFETGPAMASRQVDIATQGWFIGLMCAVALLILILL 1161
Query 638 LFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMY---SDGNFTDVSVV 694
+ CF +R+ P + DG F + +
Sbjct 1162 IVCFIRRNK-----------------GGKYPVKEKEDAHADPEIQPMKEDDGTFGEYRSL 1204
Query 695 EIEANDKKP 703
E +A D KP
Sbjct 1205 ESDAEDHKP 1213
>sp|E1C8P7|DSCL1_CHICK Cell adhesion molecule DSCAML1 OS=Gallus
gallus OX=9031 GN=DSCAML1 PE=1 SV=2
Length=2042
Score = 219 bits (557), Expect = 2e-57, Method: Composition-based stats.
Identities = 102/518 (20%), Positives = 182/518 (35%), Gaps = 44/518 (8%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
K L+C + + W+ G +T ++ + ++ AT D +V
Sbjct 807 KELNCTARGERPIIIRWEKG-DTVIDPDRNMRYAIATKDNGDEVISTLKLKP-ADRGDSV 864
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+F A N+ G+ D + P+PP + E + + L WT
Sbjct 865 FFSCH-----AINSYGE---DRGLIQLTVQEPPDPPE---LEIREVKARSMNLRWTQRFD 913
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ II ++I+Y+ K S + + + T + + DL P + Y R+ + G+
Sbjct 914 GNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGR-- 971
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
S+ S+E + T E P P + P +Q ++Q+ WK NG I Y++
Sbjct 972 -SEPSKELTISTEEAAPDGPP-MDVTLQPMTSQ---SIQVTWKAPKKELQNGVIRGYQIG 1026
Query 370 LTRWKSHLQ--------NYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAA--VLTIP 417
T ++ T++ +Y + N G ++ +
Sbjct 1027 YRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATT 1086
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL-EWCVLSDKAPCITDW---QQE 473
D + P ++ + W+ P S +L + V+ +W Q
Sbjct 1087 LEDVPSQPPENVRAISITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYMDGEWGEMQNI 1146
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI-KAYLKQAPPSKGPTVRTKKVGK 532
T R LRG + + Y + V G G S+ K+ P ++
Sbjct 1147 TTTRERVELRG-MEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDIPGPPAGIKAVPSSA 1205
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYTLSSLTSDTLYM 589
+ V+ W LP NG IR YTIF + + + Y ++ L YM
Sbjct 1206 SSVVVSW--LPPAKPNGIIRKYTIFCSSPGSGQPAPSEYETSPDQLFYRIAHLNRGQQYM 1263
Query 590 VRMAAYTDEGGKDGPEFTFTTPKF-AQGEIEAIVVPVC 626
+ +AA T G + E P A +I + V
Sbjct 1264 LWVAAVTSAGRGNISEKVTIEPAGKAPAKIISFGGTVT 1301
Score = 152 bits (383), Expect = 5e-36, Method: Composition-based stats.
Identities = 91/509 (18%), Positives = 165/509 (32%), Gaps = 52/509 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDG-------GRETHLETNFTLKSEWATHKFADCKAKRD 177
P P +++ + ++ W G + + S + +++ + K
Sbjct 987 PDGPPMDVTLQPMTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKAT 1046
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDH-INFDPVYKVKPNPPHNLSVINSEEL 236
+ + F V V+A N G S IN + V PP N+ I+
Sbjct 1047 GDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRAISI--T 1104
Query 237 SSILKLTWTNPSIK--SVIILKYN-IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
S + ++W+ P + ++ Y I + W ++ ++ +TR ++ ++ FT
Sbjct 1105 SDVAVISWSEPPRSTLNGVLKGYRVIFWSLYMDGEWGEM--QNITTTRERVELRGMEKFT 1162
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
Y ++ + G G S T ED P + + W
Sbjct 1163 NYSVQVLAYTQAGDGV---RSSVLYIQTKEDIPGPPAGIKAVPSSASSVVV-----SW-- 1212
Query 354 LPPFEANGKILDYEVTLTRWKSHLQNYTVNATK-------LTVNLTNDRYLATLTVRNLV 406
LPP + NG I Y + + S + T + +Y+ +
Sbjct 1213 LPPAKPNGIIRKYTIFCSSPGSGQPAPSEYETSPDQLFYRIAHLNRGQQYMLWVAAVTSA 1272
Query 407 GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEW----TTPRESVKKYI--LEWCVL 460
G+ + + +A ++ + W P SV + + ++W
Sbjct 1273 GRGNISEKVTIEPAGKAPAKIISF-----GGTVTTPWMKDVRLPCNSVGEPVPAIKWTKD 1327
Query 461 SDKA--PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
S+ + P D + LR AE Y A ++I L
Sbjct 1328 SEDSAIPVTVDGHRLIQANGTLVLRSVKAEDSGY----YTCTATNTWGFDTIIINLLVQV 1383
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEY 577
P P + K + L W +P D IR + + Y E V + SS +
Sbjct 1384 PPDQPRLTVSKTSASSITLAW--IPGDNGGSSIRGFVLQYSVDNSEEWKDVFISSSERSF 1441
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
L SL T Y V++AA G E
Sbjct 1442 KLESLKCGTWYKVKLAAKNSVGAGRISEI 1470
Score = 114 bits (285), Expect = 2e-24, Method: Composition-based stats.
Identities = 90/546 (16%), Positives = 174/546 (32%), Gaps = 64/546 (12%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-----TNF 158
N G + T+ +P + P+N+ I W + L
Sbjct 1071 NRAGTGPSSSEINATTLE-DVPSQPPENVRAISITSDVAVISWSEPPRSTLNGVLKGYRV 1129
Query 159 TLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVY 218
S + ++ + + T + F N V V A G + +
Sbjct 1130 IFWSLYMDGEWGEMQNITTTRERVELRGME-KFTNYSVQVLAYTQAGDGVRSSVLYIQTK 1188
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
+ P PP + + S S ++ W P+ + II KY I + + + E T+
Sbjct 1189 EDIPGPPAGIKAVPSSASSVVVS--WLPPAKPNGIIRKYTIFCSSPGSGQPAPSEYE-TS 1245
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+ + + L +Y+ + + G+G SE+ + P+K SF +
Sbjct 1246 PDQLFYRIAHLNRGQQYMLWVAAVTSAGRGNI---SEKVTIEPAGKAPAKIISFGGTVTT 1302
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK-----LTVNLT- 392
+ R P + G+ V +W ++ + T + N T
Sbjct 1303 PWMKDVR---------LPCNSVGEP----VPAIKWTKDSEDSAIPVTVDGHRLIQANGTL 1349
Query 393 -------NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT 445
D T T N G + + P + + + + + W
Sbjct 1350 VLRSVKAEDSGYYTCTATNTWGFDTIIINLL--VQVPPDQPRLTVSKTSASS-ITLAWIP 1406
Query 446 PRE---SVKKYILEWCVLSDKAPCITDWQQE-DGTVHRTYLRGNLAESKCYLITVTPVYA 501
S++ ++L++ V + + W+ + R++ +L Y + + +
Sbjct 1407 GDNGGSSIRGFVLQYSVDNSEE-----WKDVFISSSERSFKLESLKCGTWYKVKLAAKNS 1461
Query 502 DGPGS-PESIKAYL--KQAPPSKGPTV-RTKKVGKNEAVLE-WDQLPVDVQNGFIRNYTI 556
G G E I+A ++ SK + L+ W I +
Sbjct 1462 VGAGRISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGW-----SSGGCPITAIVL 1516
Query 557 FYRTIIGNETAVNVDSSHT-EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ 615
YR GN ++ ++ + E L+ L T Y +RM A G + F T +
Sbjct 1517 EYRPK-GNWGWQSLRTNSSGEVFLTELREATWYELRMKACNSAGCGN-ESTQFATLDYDG 1574
Query 616 GEIEAI 621
I I
Sbjct 1575 STIPPI 1580
Score = 74.1 bits (180), Expect = 5e-12, Method: Composition-based stats.
Identities = 45/243 (19%), Positives = 76/243 (31%), Gaps = 23/243 (9%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A N G D I + + +V P+ P L+V + +S + L W I +
Sbjct 1365 TATNTWG---FDTIIINLLVQVPPDQPR-LTVSKT--SASSITLAWIPGDNGGSSIRGFV 1418
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+QY ++ W + +S+ SF ++ LK T Y ++ G G SE
Sbjct 1419 LQYSVDNSEEWKDV---FISSSERSFKLESLKCGTWYKVKLAAKNSVGAGRI---SEIIE 1472
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
T+ PS + + T +Q W I + +
Sbjct 1473 AKTHGREPSFSKDQHLFTHINSTHARLNLQ-GW-----SSGGCPITAIVLEYRPKGNWGW 1526
Query 379 NYTVNATKLTVNLTNDR----YLATLTVRNLVGKS-DAAVLTIPACDFQATHPVMDLKAF 433
+ V LT R Y + N G ++ D P+ +
Sbjct 1527 QSLRTNSSGEVFLTELREATWYELRMKACNSAGCGNESTQFATLDYDGSTIPPIKSAQGE 1586
Query 434 PKD 436
D
Sbjct 1587 GDD 1589
Score = 65.6 bits (158), Expect = 2e-09, Method: Composition-based stats.
Identities = 60/480 (13%), Positives = 132/480 (28%), Gaps = 47/480 (10%)
Query 63 NYIVW--KTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI 120
I W + + T + ++Q+ + +V I
Sbjct 1128 RVIFWSLYMDGEWGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQT 1187
Query 121 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRET-HLETNFTLKSEWATHKFADCKAKRDTP 179
+ P P + + + + W + + +T+ +P
Sbjct 1188 KEDI-PGPPAGIKAVPSSASSVVVSWLPPAKPNGIIRKYTIFCSSPGSGQPAPSEYETSP 1246
Query 180 TSCTVDYSTV-YFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELS 237
+ + +WV A + G+ S+ + +P K +I+
Sbjct 1247 DQLFYRIAHLNRGQQYMLWVAAVTSAGRGNISEKVTIEPAGKAPA------KIISFGGTV 1300
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD--LKPFTEY 295
+ + + + + +D+ + TV L
Sbjct 1301 TTPWMK------------DVRLPCNSVGEPVPAIKWTKDSEDSAIPVTVDGHRLIQANGT 1348
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDR--PSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
+ +R +K + GY++ + G + P ++ S T ++ L W
Sbjct 1349 LV-LRSVKAEDSGYYTCTATNTWGFDTIIINLLVQVPPDQPRLTVSKTSAS-SITLAW-- 1404
Query 354 LPPFEANGKILDYEVTLT-----RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK 408
+P I + + + WK + + + KL Y L +N VG
Sbjct 1405 IPGDNGGSSIRGFVLQYSVDNSEEWKDVFISSSERSFKLESLKCGTWYKVKLAAKNSVGA 1464
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE-----WTTPRESVKKYILEWCVLSDK 463
+ + + D F N W++ + +LE+ +
Sbjct 1465 GRISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWSSGGCPITAIVLEYRPKGNW 1524
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
WQ L E+ Y + + + G G+ + A L + P
Sbjct 1525 G-----WQSLRTNSSGEVFLTELREATWYELRMKACNSAGCGNESTQFATLDYDGSTIPP 1579
>sp|Q9UMZ3|PTPRQ_HUMAN Phosphatidylinositol phosphatase PTPRQ
OS=Homo sapiens OX=9606 GN=PTPRQ PE=1 SV=2
Length=2332
Score = 218 bits (554), Expect = 6e-57, Method: Composition-based stats.
Identities = 108/602 (18%), Positives = 204/602 (34%), Gaps = 39/602 (6%)
Query 53 KCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDI---ASLNIQLTC-NILTF 108
K + N I+ + + IN T +S+ +D+ + +T
Sbjct 914 KLSWQPPLEPNGIILYYTVYVWNRSSLKTINVTETSLELSDLDYNVEYSAYVTASTRFGD 973
Query 109 GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSE 163
G+ N+ G P + PK++ + W G + + S
Sbjct 974 GKTRSNIISFQTPEGAPSDPPKDVYYANLSSSSIILFWTPPSKPNGIIQYYSVYYRNTSG 1033
Query 164 WATHKFADCKAKRDTPT---SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKV 220
F + D S +D T+ F W+ A ++G + VY
Sbjct 1034 TFMQNFTLHEVTNDFDNMTVSTIIDKLTI-FSYYTFWLTASTSVGNGNKSS-DIIEVYTD 1091
Query 221 KPNPPHNLSVINSEELSSI-LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
+ P + + E +SS + ++W P+ + ++ Y T + P +
Sbjct 1092 QDIPEGFVGNLTYESISSTAINVSWVPPAQPNGLVFYY---VSLILQQTPRHVRP-PLVT 1147
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
S +L+ +T+Y+ +I E KG+ ++ + T ED P +P I+
Sbjct 1148 YERSIYFDNLEKYTDYILKITPSTE--KGFSDTYTAQLYIKTEEDVPETSP----IINTF 1201
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL-TNDRYLA 398
+V L W PP + NG I+ Y++TL + T + + L Y
Sbjct 1202 KNLSSTSVLLSWD--PPVKPNGAIISYDLTLQGPNENYSFITSDNYIILEELSPFTLYSF 1259
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEW 457
R G +++L + P +L + +W++W+ +
Sbjct 1260 FAAARTRKGLGPSSILFFYTDESVPLAPPQNLTLINCTSDFVWLKWSPSPLPGGIVKVYS 1319
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES--IKAYLK 515
+ + ++ G L G L Y I V+ G G+ S +K +
Sbjct 1320 FKIHEHETDTIYYKNISGFKTEAKLVG-LEPVSTYSIRVSAFTKVGNGNQFSNVVKFTTQ 1378
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT 575
++ P ++ +++WD P NG I Y + T+ N T V
Sbjct 1379 ESVPDVVQNMQCMATSWQSVLVKWD--PPKKANGIITQYMV---TVERNSTK--VSPQDH 1431
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLL 635
YT L ++T Y+ ++ A T G D +T + + + TL
Sbjct 1432 MYTFIKLLANTSYVFKVRASTSAGEGDESTCHVSTLPETVPSVPTNIAFSDVQSTSATLT 1491
Query 636 GV 637
+
Sbjct 1492 WI 1493
Score = 198 bits (504), Expect = 9e-51, Method: Composition-based stats.
Identities = 96/504 (19%), Positives = 174/504 (35%), Gaps = 47/504 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P K ++ + WD + T + +A + + T + +
Sbjct 610 VPSSIKIINYKNISSSSILLYWDPPE--YPNGKITHYTIYAMELDTNRAFQITTIDNSFL 667
Query 185 DYSTVYFVNIEVWVEAENALG--KVTSDHINFDPVYKVKPNP-PHNLSVINSEELSSILK 241
+ ++ V A +G ++ ++ F + +P P ++ VI+ + ++
Sbjct 668 ITGLKKYTKYKMRVAASTHVGESSLSEENDIFVRTSEDEPESSPQDVEVIDV--TADEIR 725
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
L W+ P + II+ Y + Y+ D ++ + +++L+P T Y +R
Sbjct 726 LKWSPPEKPNGIIIAYEVLYKNIDTLYMKN-------TSTTDIILRNLRPHTLYNISVRS 778
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
G G S S T E P AP + S + + LPP NG
Sbjct 779 YTRFGHGN--QVSSLLSVRTSETVPDSAPENITYKNISSGEIELS------FLPPSSPNG 830
Query 362 KILDYEVTLTRWKSHLQNYTVNATKLTVNL----TNDRYLATLTVRNLVGKS-DAAVLTI 416
I Y + L R + + T+N T LT N+ +Y+ ++ L G+ +A ++I
Sbjct 831 IIKKYTIYLKRSNGNEER-TINTTSLTQNIKVLKKYTQYIIEVSASTLKGEGVRSAPISI 889
Query 417 PACDFQATHPVMDLKAFPKDNMLW-VEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
+ P D + + W P E IL + V +
Sbjct 890 LTEEDAPDSPPQDFSVKQLSGVTVKLSWQPPLEP-NGIILYYTVYVWNRSSLKTINV--- 945
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPES--IKAYLKQAPPSKGP-TVRTKKVGK 532
+ +L + Y VT G G S I + PS P V +
Sbjct 946 -TETSLELSDLDYNVEYSAYVTASTRFGDGKTRSNIISFQTPEGAPSDPPKDVYYANLSS 1004
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG--------NETAVNVDSSHTEYTLSSLTS 584
+ +L W P NG I+ Y+++YR G +E + D+ + LT
Sbjct 1005 SSIILFW--TPPSKPNGIIQYYSVYYRNTSGTFMQNFTLHEVTNDFDNMTVSTIIDKLTI 1062
Query 585 DTLYMVRMAAYTDEGGKDGPEFTF 608
+ Y + A T G +
Sbjct 1063 FSYYTFWLTASTSVGNGNKSSDII 1086
Score = 188 bits (477), Expect = 2e-47, Method: Composition-based stats.
Identities = 101/560 (18%), Positives = 180/560 (32%), Gaps = 42/560 (8%)
Query 75 PKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSC 134
+ + T + I+++ + L + I P P++ S
Sbjct 846 EERTINTTSLTQNIKVLKKYTQYIIEVSASTLKGEGVRSAPISILTEEDAPDSPPQDFSV 905
Query 135 IVNEGKKMRCEWDGGRET-HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV-YFV 192
G ++ W E + +T+ + K T +++ S + Y V
Sbjct 906 KQLSGVTVKLSWQPPLEPNGIILYYTVYV------WNRSSLKTINVTETSLELSDLDYNV 959
Query 193 NIEVWVEAENALG--KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+V A G K S+ I+F +PP + V + SS + L WT PS
Sbjct 960 EYSAYVTASTRFGDGKTRSNIISFQTPEGAPSDPPKD--VYYANLSSSSIILFWTPPSKP 1017
Query 251 SVIILKYNIQYRTKDASTWSQIP----PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ II Y++ YR + D + S + L F+ Y F + G
Sbjct 1018 NGIIQYYSVYYRNTSGTFMQNFTLHEVTNDFDNMTVSTIIDKLTIFSYYTFWLTASTSVG 1077
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
G S S+ T +D P F + + + + W +PP + NG + Y
Sbjct 1078 NGNKS--SDIIEVYTDQDIPEG---FVGNLTY-ESISSTAINVSW--VPPAQPNGLVFYY 1129
Query 367 E-VTLTRWKSHL--QNYTVNATKLTVNLTN-DRYLATLTVRNLVGKSDAAVLTI---PAC 419
+ L + H+ T + NL Y+ +T G SD +
Sbjct 1130 VSLILQQTPRHVRPPLVTYERSIYFDNLEKYTDYILKITPSTEKGFSDTYTAQLYIKTEE 1189
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
D T P+++ + + W P + I L + T
Sbjct 1190 DVPETSPIINTFKNLSSTSVLLSWDPPVKPNGAIISYDLTLQGPNENYSFI-----TSDN 1244
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLE 538
+ L+ Y G G + Y ++ P P + + L+
Sbjct 1245 YIILEELSPFTLYSFFAAARTRKGLGPSSILFFYTDESVPLAPPQNLTLINCTSDFVWLK 1304
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
W P+ G ++ Y+ + N+ TE L L + Y +R++A+T
Sbjct 1305 WSPSPL--PGGIVKVYSFKIHEHETDTIYYKNISGFKTEAKLVGLEPVSTYSIRVSAFTK 1362
Query 598 EGGKD--GPEFTFTTPKFAQ 615
G + FTT +
Sbjct 1363 VGNGNQFSNVVKFTTQESVP 1382
Score = 187 bits (475), Expect = 3e-47, Method: Composition-based stats.
Identities = 96/597 (16%), Positives = 188/597 (31%), Gaps = 60/597 (10%)
Query 53 KCMDYFHVNANYIVWKTNHFTIPKEQYTI---INRTASSVTFTDIASLNIQLT----CNI 105
N +V+ + + + + S+ F ++ +
Sbjct 1113 NVSWVPPAQPNGLVFYYVSLILQQTPRHVRPPLVTYERSIYFDNLEKYTDYILKITPSTE 1172
Query 106 LTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA 165
F I +P P + + WD + N + S
Sbjct 1173 KGFSDTYTAQLYIKTEEDVPETSPIINTFKNLSSTSVLLSWDPPVKP----NGAIISYDL 1228
Query 166 THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPP 225
T + + T + + F + A G S + F V PP
Sbjct 1229 TLQGPNENYSFITSDNYIILEELSPFTLYSFFAAARTRKGLGPSSILFFYTDESVPLAPP 1288
Query 226 HNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
NL++IN S + L W+ + I+ Y+ + + T I ++ + ++
Sbjct 1289 QNLTLINC--TSDFVWLKWSPSPLPGGIVKVYSFKIHEHETDT---IYYKNISGFKTEAK 1343
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
+ L+P + Y R+ + G G +S T E P + ++
Sbjct 1344 LVGLEPVSTYSIRVSAFTKVGNGN--QFSNVVKFTTQESVPD-----VVQNMQCMATSWQ 1396
Query 346 TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNL 405
+V + W PP +ANG I Y VT+ R + + T L N Y+ +
Sbjct 1397 SVLVKWD--PPKKANGIITQYMVTVERNSTKVSPQDHMYT-FIKLLANTSYVFKVRASTS 1453
Query 406 VGKSDAAVLTIPACDFQATHPVMDLK-AFPKDNMLWVEWTTPRESVKKYILEWCVLSD-K 463
G+ D + + ++ + + + W P +++ Y + + + +
Sbjct 1454 AGEGDESTCHVSTLPETVPSVPTNIAFSDVQSTSATLTWIRP-DTILGYFQNYKITTQLR 1512
Query 464 APCITDWQQED-------GTVHRTYLRG----NLAESKCYLITVTPVYADGPGSPESIKA 512
A +W+ E+ ++ +L L + + Y V G G+ + +
Sbjct 1513 AQKCKEWESEECVEYQKIQYLYEAHLTEETVYGLKKFRWYRFQVAASTNAGYGNASNWIS 1572
Query 513 Y-LKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRN---YTIFYRTIIGNETA 567
PP P V + W + I Y I +++ +E
Sbjct 1573 TKTLPGPPDGPPENVHVVATSPFSISISWSEP------AVITGPTCYLIDVKSVDNDEFN 1626
Query 568 VN-VDSSHTEYTLS--SLTSDTLYMVRMAAYTD------EGGKDGPEFTFTTPKFAQ 615
++ + S+ T+ L T Y V + A+T GK E TT + A
Sbjct 1627 ISFIKSNEENKTIEIKDLEIFTRYSVVITAFTGNISAAYVEGKSSAEMIVTTLESAP 1683
Score = 179 bits (454), Expect = 1e-44, Method: Composition-based stats.
Identities = 93/509 (18%), Positives = 185/509 (36%), Gaps = 43/509 (8%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD 177
+ P P+++ I ++R +W + N + + +K D ++
Sbjct 700 VRTSEDEPESSPQDVEVIDVTADEIRLKWSPPEKP----NGIIIAYEVLYKNIDTLYMKN 755
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVT--SDHINFDPVYKVKPNPPHNLSVINSEE 235
T T+ + + + V + G S ++ V + P N++ N
Sbjct 756 TSTTDIILRNLRPHTLYNISVRSYTRFGHGNQVSSLLSVRTSETVPDSAPENITYKNI-- 813
Query 236 LSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
S ++L++ PS + II KY I + + + I +T S + V LK +T+Y
Sbjct 814 SSGEIELSFLPPSSPNGIIKKYTIYLKRSNGNEERTI---NTTSLTQNIKV--LKKYTQY 868
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
+ + G+G S S +T ED P P + S TV+L W+ P
Sbjct 869 IIEVSASTLKGEGV---RSAPISILTEEDAPDSPPQDFSVKQLSGV----TVKLSWQ--P 919
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLV------GKS 409
P E NG IL Y V + T+N T+ ++ L++ Y + GK+
Sbjct 920 PLEPNGIILYYTVYVWN---RSSLKTINVTETSLELSDLDYNVEYSAYVTASTRFGDGKT 976
Query 410 DAAVLTIPACDFQATHPVMDL-KAFPKDNMLWVEWTTPRES---VKKYILEWCVLSD--- 462
+ +++ + + P D+ A + + + WT P + ++ Y + + S
Sbjct 977 RSNIISFQTPEGAPSDPPKDVYYANLSSSSIILFWTPPSKPNGIIQYYSVYYRNTSGTFM 1036
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES--IKAYLKQAPPS 520
+ + + + + + + L Y +T + G G+ S I+ Y Q P
Sbjct 1037 QNFTLHEVTNDFDNMTVSTIIDKLTIFSYYTFWLTASTSVGNGNKSSDIIEVYTDQDIPE 1096
Query 521 K-GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTL 579
+ + + + W +P NG + Y + +
Sbjct 1097 GFVGNLTYESISSTAINVSW--VPPAQPNGLVFYYVSLILQQTPRHVRPPLVTYERSIYF 1154
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
+L T Y++++ T++G D
Sbjct 1155 DNLEKYTDYILKITPSTEKGFSDTYTAQL 1183
Score = 168 bits (425), Expect = 5e-41, Method: Composition-based stats.
Identities = 125/672 (19%), Positives = 219/672 (33%), Gaps = 86/672 (13%)
Query 208 TSDHINFDPVYKVKPNPPHNLSVINSEELSSILK-------------LTWTNPSIKSVII 254
T I+ + PP LSV +++ S +K L W P + I
Sbjct 582 TEHMISVSAFTIMGEGPPTVLSVRTRQQVPSSIKIINYKNISSSSILLYWDPPEYPNGKI 641
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
Y I D + QI D +SF + LK +T+Y R+ G+ S+
Sbjct 642 THYTIYAMELDTNRAFQITTID-----NSFLITGLKKYTKYKMRVAASTHVGESSLSE-E 695
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK 374
+ T ED P +P ID + ++L W PP + NG I+ YEV
Sbjct 696 NDIFVRTSEDEPESSPQDVEVIDVTAD----EIRLKWS--PPEKPNGIIIAYEVLYKNID 749
Query 375 SHLQNYTVNATKLTVNL-TNDRYLATLTVRNLVGKSD--AAVLTIPACDFQATHPVMDLK 431
+ T + NL + Y ++ G + +++L++ + ++
Sbjct 750 TLYMKNTSTTDIILRNLRPHTLYNISVRSYTRFGHGNQVSSLLSVRTSETVPDSAPENIT 809
Query 432 AFPKDN-MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN---LA 487
+ + + + P S I ++ + ++ E+ T++ T L N L
Sbjct 810 YKNISSGEIELSFLPPS-SPNGIIKKYTIYLKRSNG-----NEERTINTTSLTQNIKVLK 863
Query 488 ESKCYLITVTPVYADGPG-SPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVD 545
+ Y+I V+ G G I ++ P P K++ L W P
Sbjct 864 KYTQYIIEVSASTLKGEGVRSAPISILTEEDAPDSPPQDFSVKQLSGVTVKLSWQ--PPL 921
Query 546 VQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD--EGGKDG 603
NG I YT++ + + ++ + T LS L + Y + A T +G
Sbjct 922 EPNGIILYYTVY---VWNRSSLKTINVTETSLELSDLDYNVEYSAYVTASTRFGDGKTRS 978
Query 604 PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHI 663
+F TP+ A + P + + F P+ P+ I
Sbjct 979 NIISFQTPEGAPSD------PPKDVYYANLSSSSIILFWTP--------PSKPN----GI 1020
Query 664 AQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEG 723
Q+ + D + + K + L +
Sbjct 1021 IQYYSVYYRNTSGTFMQNFTLHEVTNDFDNMTVSTIIDKLTIFSYYTFWLTASTSVGNGN 1080
Query 724 HSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQY--------------STVVHSGYRH 769
SS I + ES +T+ V + S ++ RH
Sbjct 1081 KSSDIIEVYTDQDIPEGFVGNLTYESISSTAINVSWVPPAQPNGLVFYYVSLILQQTPRH 1140
Query 770 QVPSVQVFSRSESTQPLLDSEERPED--LQLVDHVDGG-DGILPRQQYFKQNCSQHESSP 826
P + + RS D+ E+ D L++ + G Q Y K E+SP
Sbjct 1141 VRPPLVTYERS----IYFDNLEKYTDYILKITPSTEKGFSDTYTAQLYIKTEEDVPETSP 1196
Query 827 DISHFERSKQVS 838
I+ F+ S
Sbjct 1197 IINTFKNLSSTS 1208
Score = 153 bits (385), Expect = 2e-36, Method: Composition-based stats.
Identities = 70/336 (21%), Positives = 127/336 (38%), Gaps = 29/336 (9%)
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
D A+ + S+ ++ L PFTE++ + G+G S T + PS K
Sbjct 565 DIAAEQLSYVIRRLVPFTEHMISVSAFTIMGEGPP----TVLSVRTRQQVPSS-----IK 615
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL--QNYTVNATKLTVNLTN 393
I ++ L W PP NGKI Y + ++ Q T++ + L L
Sbjct 616 IINYKNISSSSILLYWD--PPEYPNGKITHYTIYAMELDTNRAFQITTIDNSFLITGLKK 673
Query 394 -DRYLATLTVRNLVGK---SDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRE 448
+Y + VG+ S+ + + + + D++ + + ++W+ P E
Sbjct 674 YTKYKMRVAASTHVGESSLSEENDIFVRTSEDEPESSPQDVEVIDVTADEIRLKWSPP-E 732
Query 449 SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPV--YADGPGS 506
I+ + VL T + + T + NL Y I+V + G
Sbjct 733 KPNGIIIAYEVLY--KNIDTLYMKNTSTTD--IILRNLRPHTLYNISVRSYTRFGHGNQV 788
Query 507 PESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE 565
+ + P P + K + E L LP NG I+ YTI+ + GNE
Sbjct 789 SSLLSVRTSETVPDSAPENITYKNISSGEIELS--FLPPSSPNGIIKKYTIYLKRSNGNE 846
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
++++ + L T Y++ ++A T +G
Sbjct 847 -ERTINTTSLTQNIKVLKKYTQYIIEVSASTLKGEG 881
Score = 144 bits (364), Expect = 9e-34, Method: Composition-based stats.
Identities = 85/565 (15%), Positives = 161/565 (28%), Gaps = 73/565 (13%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFAD---CKAKRDTP 179
+P P+NL+ I + +W L + H+
Sbjct 1282 SVPLAPPQNLTLINCTSDFVWLKWSPSP---LPGGIVKVYSFKIHEHETDTIYYKNISGF 1338
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVT--SDHINFDPVYKVKPNPPHNLSVINSEELS 237
+ + V A +G S+ + F V P+ N+ + +
Sbjct 1339 KTEAKLVGLEPVSTYSIRVSAFTKVGNGNQFSNVVKFTTQESV-PDVVQNMQCMAT--SW 1395
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ + W P + II +Y + + +T L T YVF
Sbjct 1396 QSVLVKWDPPKKANGIITQYMVTVERNSTK---------VSPQDHMYTFIKLLANTSYVF 1446
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
++R G+G S T P PS I S Q + L W + P
Sbjct 1447 KVRASTSAGEGDEST----CHVSTL---PETVPSVPTNIAFSDVQST-SATLTW--IRPD 1496
Query 358 EANGKILDYEVT-------LTRWKSHL--------QNYTVNATKLTVNLTNDR--YLATL 400
G +Y++T W+S Y + T+ TV Y +
Sbjct 1497 TILGYFQNYKITTQLRAQKCKEWESEECVEYQKIQYLYEAHLTEETVYGLKKFRWYRFQV 1556
Query 401 TVRNLVGKS-DAAVLTIPACDFQATHPVMDLKAFPKDN-MLWVEWTTPRESVKK--YILE 456
G + ++ P ++ + + W+ P Y+++
Sbjct 1557 AASTNAGYGNASNWISTKTLPGPPDGPPENVHVVATSPFSISISWSEPAVITGPTCYLID 1616
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG------SPESI 510
+ + I+ + + +T +L Y + +T + S +
Sbjct 1617 VKSVDNDEFNISFIKSNEEN--KTIEIKDLEIFTRYSVVITAFTGNISAAYVEGKSSAEM 1674
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAV-LEWDQLPVDVQNGFIRNY-TIFYRTIIGNETAV 568
++ P P T + +E + LP NG I+ Y + YR +
Sbjct 1675 IVTTLESAPKDPPNNMTFQKIPDEVTKFQLTFLPPSQPNGNIQVYQALVYREDDPTAVQI 1734
Query 569 N---VDSSHTEYT---LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIV 622
+ + + L L Y + + A G T A +
Sbjct 1735 HNLSIIQKTNTFVIAMLEGLKGGHTYNISVYAVNSAGAGPKVPMRITMDIKAPARPKTKP 1794
Query 623 VPV---CLAFLLTTLLGVLF---CF 641
P+ L+T+ + C+
Sbjct 1795 TPIYDATGKLLVTSTTITIRMPICY 1819
Score = 138 bits (348), Expect = 8e-32, Method: Composition-based stats.
Identities = 75/522 (14%), Positives = 156/522 (30%), Gaps = 56/522 (11%)
Query 109 GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH----LETNFTLKSEW 164
G ++ + +P NL+ + W + + + L+
Sbjct 1079 GNKSSDIIEVYTDQDIPEGFVGNLTYESISSTAINVSWVPPAQPNGLVFYYVSLILQQTP 1138
Query 165 ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN--ALGKVTSDHINFDPVYKVKP 222
+ +R + + + + + + + V
Sbjct 1139 RHVRPPLVTYERS-----IYFDNLEKYTDYILKITPSTEKGFSDTYTAQLYIKTEEDVPE 1193
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P + N S+ + L+W P + I+ Y++ + + + ++ +
Sbjct 1194 TSPIINTFKNL--SSTSVLLSWDPPVKPNGAIISYDLTLQGPNEN-------YSFITSDN 1244
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
+++L PFT Y F G G S T E P P I+ +
Sbjct 1245 YIILEELSPFTLYSFFAAARTRKGLG----PSSILFFYTDESVPLAPPQNLTLINCTSDF 1300
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS---HLQNYTVNATKLTVNLTNDRYLAT 399
V L W P K+ +++ + + KL Y
Sbjct 1301 ----VWLKWSPSPLPGGIVKVYSFKIHEHETDTIYYKNISGFKTEAKLVGLEPVSTYSIR 1356
Query 400 LTVRNLVGKS-DAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRESVKKYILEW 457
++ VG + + V +++ + V+W P+++ I ++
Sbjct 1357 VSAFTKVGNGNQFSNVVKFTTQESVPDVVQNMQCMATSWQSVLVKWDPPKKA-NGIITQY 1415
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA-YLKQ 516
V ++ + T+++ L + Y+ V + G G + L +
Sbjct 1416 MVTVERNST----KVSPQDHMYTFIK--LLANTSYVFKVRASTSAGEGDESTCHVSTLPE 1469
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN------ETAV-- 568
PS + V A L W + D G+ +NY I + E V
Sbjct 1470 TVPSVPTNIAFSDVQSTSATLTW--IRPDTILGYFQNYKITTQLRAQKCKEWESEECVEY 1527
Query 569 -----NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
++ TE T+ L Y ++AA T+ G +
Sbjct 1528 QKIQYLYEAHLTEETVYGLKKFRWYRFQVAASTNAGYGNASN 1569
Score = 138 bits (346), Expect = 1e-31, Method: Composition-based stats.
Identities = 93/535 (17%), Positives = 178/535 (33%), Gaps = 74/535 (14%)
Query 118 ITIISGLPPEKPKNLSCIVNE--GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAK 175
+ +P P+N C+ GK WD + ++ ++ + + D K
Sbjct 340 VRTPESVPEGPPQN--CVTGNITGKSFSILWDPPTIVTGKFSYRVELYGPSGRILDNSTK 397
Query 176 --RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL-SVIN 232
+ T+ T F +V++ AE + G +I+ P+ P + +
Sbjct 398 DLKFAFTNLTP------FTMYDVYIAAETSAGTGPKSNISV----FTPPDVPGAVFDLQL 447
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD-LKP 291
+E S+ +++TW P + II +Y ++ + I E+T T ++ + D + P
Sbjct 448 AEVESTQVRITWKKPRQPNGIINQYRVKVLVPETG----IILENTLLTGNNEYINDPMAP 503
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
+ +G S + Y P K T T + +
Sbjct 504 EIVNIVEPMVGLYEGSAEMSSDLHSLATFIYNSHPDKNFPA-RNRAEDQTSPVVTTRNQY 562
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA 411
T E ++ V T ++ +++ ++G+
Sbjct 563 ITDIAAEQLSYVIRRLVPFTE-----------------------HMISVSAFTIMGEGPP 599
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
VL++ + + + + + W P E I + + + T+
Sbjct 600 TVLSVRTRQQVPSSIKIINYKNISSSSILLYWDPP-EYPNGKITHYTIYA--MELDTNRA 656
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES---IKAYLKQAPP-SKGPTVRT 527
+ T+ ++L L + Y + V G S I + P S V
Sbjct 657 FQITTIDNSFLITGLKKYTKYKMRVAASTHVGESSLSEENDIFVRTSEDEPESSPQDVEV 716
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTL 587
V +E L+W P + NG I Y + Y+ I +T ++S T+ L +L TL
Sbjct 717 IDVTADEIRLKWS--PPEKPNGIIIAYEVLYKNI---DTLYMKNTSTTDIILRNLRPHTL 771
Query 588 YMVRMAAYTDEGG----------------KDGPEFTFTTPKFAQGEIEAIVVPVC 626
Y + + +YT G D T + GEIE +P
Sbjct 772 YNISVRSYTRFGHGNQVSSLLSVRTSETVPDSAPENITYKNISSGEIELSFLPPS 826
Score = 134 bits (337), Expect = 2e-30, Method: Composition-based stats.
Identities = 76/529 (14%), Positives = 143/529 (27%), Gaps = 104/529 (20%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
PE+P+ L W L + D V
Sbjct 8 PEQPEKLRAFNISTHSFSLHWSLPSGHVERYQVDLVPDSGFVTIRDLGGGEYQVDVSNVV 67
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKV-KPNPPHNLSVINSEELSSILKLTW 244
T Y + I ++ + + V KP PP L+ + L+W
Sbjct 68 PGTRYDITIS-------SISTTYTSPVTRIVTTNVTKPGPPVFLAGERVGSAG--ILLSW 118
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
P + I+ Y ++Y+ + + + +L P T Y ++
Sbjct 119 NTPPNPNGRIISYIVKYKEVCPWMQTVYTQVRSKPDSLEVLLTNLNPGTTYEIKVAAENS 178
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
G G +SD T E P K + + V+L+W P + NGKI
Sbjct 179 AGIGVFSDPF---LFQTAESAPGKVVNLTVEA-----YNASAVKLIW--YLPRQPNGKIT 228
Query 365 DYEVTLTRWKSHL--------------------------------------------QNY 380
+++++ +S +
Sbjct 229 SFKISVKHARSGIVVKDVSIRVEDILTGKLPECNENSESFLWSTASPSPTLGRVTPPSRT 288
Query 381 TVNATKLTVNLTNDRYLATLT------------------VRNLVGKSDAAVLTIPACDFQ 422
T +++ LT N + + ++ V G D+ ++ P
Sbjct 289 THSSSTLTQNEISSVWKEPISFVVTHLRPYTTYLFEVSAVTTEAGYIDSTIVRTPES-VP 347
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
P + + W P K+ + + ++ T +
Sbjct 348 EGPPQNCVTGNITGKSFSILWDPPTIVTGKFSYRVELYGPSGRIL-----DNSTKDLKFA 402
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
NL Y + + + G G +I + P ++ +V + + W
Sbjct 403 FTNLTPFTMYDVYIAAETSAGTGPKSNISVFTPPDVPGAVFDLQLAEVESTQVRITWK-- 460
Query 543 PVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS--LTSDTLYM 589
NG I Y + V T L + LT + Y+
Sbjct 461 KPRQPNGIINQYRV------------KVLVPETGIILENTLLTGNNEYI 497
>sp|Q8K3K1|USH2A_RAT Usherin OS=Rattus norvegicus OX=10116 GN=Ush2a
PE=1 SV=2
Length=5125
Score = 216 bits (550), Expect = 2e-56, Method: Composition-based stats.
Identities = 105/490 (21%), Positives = 160/490 (33%), Gaps = 71/490 (14%)
Query 181 SCTVDYSTVYFVNIEVWVEA-ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ F E+ ++A + G H+ V PP L + S
Sbjct 3815 QSAYLKNLAPFTQYEIRIQACQEGCGVSPGTHVRTLEAAPVGLMPPL-LKALGSH----C 3869
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDAST------WSQIPPEDTASTRSSFTVQDLKPFT 293
+++ WT P+ + II Y I R D WS+ E T T + L+PFT
Sbjct 3870 IEVKWTPPTRPNGIITSYVIHRRPADTEEESLLFVWSEGALEFTDDTDT------LRPFT 3923
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
Y +R+R G S WS S T E P P+ W ++ +H +V L W
Sbjct 3924 LYEYRVRAWNSKGV-VDSPWS---SVQTLEAPPQDLPAPWVQVTSAH-----SVLLNWTE 3974
Query 354 LPPFEANGKILDYEVTLTR-------WKSHLQNYTVNATKLTVNLTN----DRYLATLTV 402
P NG I Y V S + +TV + +L Y +
Sbjct 3975 --PEAPNGLISQYHVIYQERPDEAAPGSSTVHAFTVKGSSRQAHLFGLEPFTTYHIGVAA 4032
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM--LWVEWTTPRESVKKYILEWCVL 460
N GK + I + A +M+ A ++ L ++W+ P I + V
Sbjct 4033 VNRAGKVSSPWTLIKTLE-SAPSGLMNFTAEQREGGRALLLQWSEPV-RTNGVIKAYNVF 4090
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS 520
SD P E + R +L LA Y++T+ A G + ++APP
Sbjct 4091 SDGLP-------EYSGLGRQFLFRRLAPFTLYILTLEACTAAGCAHSVPQTLWTEEAPPD 4143
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNVDSSHTEY-- 577
+ V L W Q NG I Y + R + G V +
Sbjct 4144 SQMAPTIQSVEPTSVRLHWSQ--PANPNGKIIRYEVIRRRLQGEDWGNRTVQADENTVFT 4201
Query 578 -----------TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT----PKFAQGEIEAIV 622
T + L LY R+ + G T P + V
Sbjct 4202 EYNTEGNGWVCTDTGLQPWGLYSYRICTWNSAGHTCSSWSVVRTSQAPPDGLSPPEVSYV 4261
Query 623 VPVCLAFLLT 632
L L++
Sbjct 4262 STSPLQLLIS 4271
Score = 207 bits (527), Expect = 2e-53, Method: Composition-based stats.
Identities = 111/499 (22%), Positives = 175/499 (35%), Gaps = 48/499 (10%)
Query 142 MRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
+ W + + T++ L + +F S T ++A
Sbjct 3505 IFLTWKEPTQSNGPITHYILLRD-GRERFQ------GAALSFTDTQGIQPLQEYSYQLKA 3557
Query 201 ENALGKVTSDHINFDPVYKV-KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A G S + V + PP N++ + E L L+W+ P ++ I +Y +
Sbjct 3558 CTAAGCADSCKVVATATRGVLESVPPPNITAQSPE----TLHLSWSVPEKRNDAIKEYQL 3613
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
K + DT R TV L+P T Y F + G SE + G
Sbjct 3614 WLDGKG------LIYTDTND-RRQHTVTGLQPHTNYSFTLSACTSVG----CTSSEPSVG 3662
Query 320 ITYEDRPSKAPSFWYKIDPSHTQ-GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
T + P W + P H TV+L W PP NG I Y + R S L
Sbjct 3663 QTLQAAPQG---VW--VTPRHIIINSTTVELYWN--PPERPNGVISQYRL--RRNGSLLL 3713
Query 379 NYTVNATKLTVNLT--NDRYLATLTVRNLVGKS--DAAVLTIPACDFQATHPVMDLKAFP 434
+ T N RY+ TL R G S + ++ +P + HP ++
Sbjct 3714 VGGRDDQSFTDKNLEPNSRYIYTLEARTGGGSSLSEEYLVQMPMWTPEDVHPPCNVTVLG 3773
Query 435 KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
D+ ++V W P + K +E+ +L + G YL+ NLA Y I
Sbjct 3774 SDS-IFVAWPAPGILLPKIPVEYSILLSGG-NMMLLTFSVGLRQSAYLK-NLAPFTQYEI 3830
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
+ +G G +A P K +G + ++W P NG I +Y
Sbjct 3831 RIQAC-QEGCGVSPGTHVRTLEAAPVGLMPPLLKALGSHCIEVKW--TPPTRPNGIITSY 3887
Query 555 TIFYRTIIGNETAVNVDSSHTEYTLSS----LTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
I R E ++ S + L TLY R+ A+ +G D P + T
Sbjct 3888 VIHRRPADTEEESLLFVWSEGALEFTDDTDTLRPFTLYEYRVRAWNSKGVVDSPWSSVQT 3947
Query 611 PKFAQGEIEAIVVPVCLAF 629
+ ++ A V V A
Sbjct 3948 LEAPPQDLPAPWVQVTSAH 3966
Score = 165 bits (417), Expect = 5e-40, Method: Composition-based stats.
Identities = 85/549 (15%), Positives = 164/549 (30%), Gaps = 54/549 (10%)
Query 94 IASLNIQL-TCNILTFGQLEQNVYGIT--IISGLPPEKPKNLSCIVNEGKKMRCEWD-GG 149
+ + QL C + V T ++ +P P N++ E + W
Sbjct 3548 LQEYSYQLKACTAAGCADSCKVVATATRGVLESVP---PPNITAQSPE--TLHLSWSVPE 3602
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS 209
+ + L + + D +R N + A ++G +S
Sbjct 3603 KRNDAIKEYQLWLDGKGLIYTDTNDRRQ-----HTVTGLQPHTNYSFTLSACTSVGCTSS 3657
Query 210 DHINFDPVYKVKPNPPHNLSVINSEE--LSSILKLTWTNPSIKSVIILKYNIQYRTKDAS 267
+ + P + V S+ ++L W P + +I +Y ++
Sbjct 3658 EPSVGQTLQ----AAPQGVWVTPRHIIINSTTVELYWNPPERPNGVISQYRLR----RNG 3709
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
+ + D SFT ++L+P + Y++ + G S SEE P
Sbjct 3710 SLLLVGGRD----DQSFTDKNLEPNSRYIYTLEARTGGG----SSLSEEYLVQM----PM 3757
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV---NA 384
P + G ++ + W P ++Y + L+ L ++V +
Sbjct 3758 WTPEDVHPPCNVTVLGSDSIFVAW-PAPGILLPKIPVEYSILLSGGNMMLLTFSVGLRQS 3816
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
L +Y + G + + + + L + + V+WT
Sbjct 3817 AYLKNLAPFTQYEIRIQA-CQEGCGVSPGTHVRTLEAAPVGLMPPLLKALGSHCIEVKWT 3875
Query 445 TPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
P + Y++ + + +G + T L Y V +
Sbjct 3876 PPTRPNGIITSYVIHRRPADTEEESLLFV-WSEGALEFTDDTDTLRPFTLYEYRVRAWNS 3934
Query 502 DGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI 561
G +APP P + + +L W + + NG I Y + Y+
Sbjct 3935 KGVVDSPWSSVQTLEAPPQDLPAPWVQVTSAHSVLLNWTE--PEAPNGLISQYHVIYQER 3992
Query 562 IGNET-------AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFA 614
A V S + L L T Y + +AA G P T + A
Sbjct 3993 PDEAAPGSSTVHAFTVKGSSRQAHLFGLEPFTTYHIGVAAVNRAGKVSSPWTLIKTLESA 4052
Query 615 QGEIEAIVV 623
+
Sbjct 4053 PSGLMNFTA 4061
Score = 161 bits (407), Expect = 7e-39, Method: Composition-based stats.
Identities = 103/560 (18%), Positives = 175/560 (31%), Gaps = 68/560 (12%)
Query 146 WDGG-RETHLETNFTLKSEWA-THKFADCKAKRDTPTSCTVDYSTVY-FVNIEVWVEAEN 202
W R + T++ + A T + + + T D T+ F E V A N
Sbjct 3874 WTPPTRPNGIITSYVIHRRPADTEEESLLFVWSEGALEFTDDTDTLRPFTLYEYRVRAWN 3933
Query 203 ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYNIQY 261
+ G V S + + PP +L + S+ + L WT P + +I +Y++ Y
Sbjct 3934 SKGVVDSPWSSVQTLE----APPQDLPAPWVQVTSAHSVLLNWTEPEAPNGLISQYHVIY 3989
Query 262 RT---KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+ + A S + + + L+PFT Y + + GK S W
Sbjct 3990 QERPDEAAPGSSTVHAFTVKGSSRQAHLFGLEPFTTYHIGVAAVNRAGK-VSSPW---TL 4045
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
T E PS +F +G R + L W P NG I Y V + L
Sbjct 4046 IKTLESAPSGLMNF----TAEQREGGRALLLQWSE--PVRTNGVIKAYNV----FSDGLP 4095
Query 379 NYTVNATKLTVNLT--NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
Y+ + Y+ TL G + + T+ + + +
Sbjct 4096 EYSGLGRQFLFRRLAPFTLYILTLEACTAAGCAHSVPQTLWTEEAPPDSQMAPTIQSVEP 4155
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED--------------GTVHRTYL 482
+ + W+ P I+ + V+ + DW
Sbjct 4156 TSVRLHWSQPANP-NGKIIRYEVIRRRLQGE-DWGNRTVQADENTVFTEYNTEGNGWVCT 4213
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP--SKGPTVRTKKVGKNEAVLEWD 540
L Y + + G QAPP P V + ++ W
Sbjct 4214 DTGLQPWGLYSYRICTWNSAGHTCSSWSVVRTSQAPPDGLSPPEVSYVSTSPLQLLISW- 4272
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
NG I++Y + G A + +SS YT L T Y + A T G
Sbjct 4273 -FAPRHTNGVIQSYRL---QRNGVFAAASFNSSTFSYTDGQLLPFTTYSYAVLACTGGGC 4328
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
TTP+ + + V+ ++ ++ P+VP
Sbjct 4329 CTSEPTNITTPEASPAGVSPPVL-------------WAIGAHQINVSWSP--PSVP---N 4370
Query 661 SHIAQWSPHTPPRHNFNSKD 680
IA++ H + +D
Sbjct 4371 GKIAKYLLHCDGEEHLAGQD 4390
Score = 159 bits (401), Expect = 4e-38, Method: Composition-based stats.
Identities = 85/439 (19%), Positives = 138/439 (31%), Gaps = 47/439 (11%)
Query 194 IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI 253
+ N+ G S + + P+ V L ++W P + +
Sbjct 4223 YSYRICTWNSAGHTCSS-WSVVRTSQAPPDGLSPPEVSYVSTSPLQLLISWFAPRHTNGV 4281
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
I Y +Q A+ S+ S+T L PFT Y + + G
Sbjct 4282 IQSYRLQRNGVFAAA-------SFNSSTFSYTDGQLLPFTTYSYAVLACTGGGCCT---- 4330
Query 314 SEEASGITYEDRPSK--APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL- 370
SE + T E P+ P W G + + W PP NGKI Y +
Sbjct 4331 SEPTNITTPEASPAGVSPPVLWAI-------GAHQINVSWS--PPSVPNGKIAKYLLHCD 4381
Query 371 TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
Q+ ++ + L +Y +L G + A A +A MD
Sbjct 4382 GEEHLAGQDLSLLLSNL---RPFTQYNVSLVACTKGGCT--ASRVASAWTMEAPPEDMDP 4436
Query 431 KAFP--KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
+ + W PR I + + D A + Y L
Sbjct 4437 PTLHVMGPESIEITWAPPRNP-HGQIRSYELRRDGA-------IVYIGLETRYHDFILTP 4488
Query 489 SKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
Y TVT + G +K + PS + + E ++ W+ P N
Sbjct 4489 GVQYGYTVTATNSRGSVLSPLVKGQTSPSAPSGLQPPKLRAGEALELLVNWN--PPVRTN 4546
Query 549 GFIRNYTIFYRT-IIGNETAVNVDSSHTEY-----TLSSLTSDTLYMVRMAAYTDEGGKD 602
G I NYT+F R + G + ++++H+ + + L Y VR+ A T G
Sbjct 4547 GKITNYTLFIRELLEGEIRTMCINTTHSSFGTRSLAVKHLKPFHRYEVRVQACTALGCTS 4606
Query 603 GPEFTFTTPKFAQGEIEAI 621
T + A
Sbjct 4607 SEWTPTQTSEIPPLLQPAP 4625
Score = 156 bits (395), Expect = 2e-37, Method: Composition-based stats.
Identities = 82/499 (16%), Positives = 147/499 (29%), Gaps = 63/499 (13%)
Query 126 PEKPKNLSCIVNEGK-KMRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P N + EG + +W R + + + F+D +
Sbjct 4053 PSGLMNFTAEQREGGRALLLQWSEPVRTNGVIKAYNV--------FSDGLPEYSGLGRQF 4104
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
+ F + +EA A G S + P+ ++ + E + ++L
Sbjct 4105 LFRRLAPFTLYILTLEACTAAGCAHSVPQTL-WTEEAPPDSQMAPTIQSVE--PTSVRLH 4161
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPE----------DTASTRSSFTVQDLKPFT 293
W+ P+ + I++Y + R W + +T T L+P+
Sbjct 4162 WSQPANPNGKIIRYEVIRRRLQGEDWGNRTVQADENTVFTEYNTEGNGWVCTDTGLQPWG 4221
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK--APSFWYKIDPSHTQGYRTVQLVW 351
Y +RI G S WS T + P P Y + + + W
Sbjct 4222 LYSYRICTWNSAGH-TCSSWS---VVRTSQAPPDGLSPPEVSYV-----STSPLQLLISW 4272
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV----NLTNDRYLATLTVRNLVG 407
P NG I Y + + N++ + L Y + G
Sbjct 4273 --FAPRHTNGVIQSYRLQR---NGVFAAASFNSSTFSYTDGQLLPFTTYSYAVLACTGGG 4327
Query 408 --KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAP 465
S+ +T P P + + + V W+ P I ++ + D
Sbjct 4328 CCTSEPTNITTPEASPAGVSPP--VLWAIGAHQINVSWSPPS-VPNGKIAKYLLHCDGEE 4384
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
+ + L NL Y +++ G + A+ +APP
Sbjct 4385 HL-------AGQDLSLLLSNLRPFTQYNVSLVACTKGGCTASRVASAWTMEAPPEDMDPP 4437
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
+G + W P +G IR+Y + + A+ T Y LT
Sbjct 4438 TLHVMGPESIEITW--APPRNPHGQIRSYEL------RRDGAIVYIGLETRYHDFILTPG 4489
Query 586 TLYMVRMAAYTDEGGKDGP 604
Y + A G P
Sbjct 4490 VQYGYTVTATNSRGSVLSP 4508
Score = 156 bits (394), Expect = 3e-37, Method: Composition-based stats.
Identities = 93/507 (18%), Positives = 150/507 (30%), Gaps = 67/507 (13%)
Query 127 EKPKNLSC---IVNEGKKMRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKR-----D 177
P++L V + W + L + + + + + A +
Sbjct 3950 APPQDLPAPWVQVTSAHSVLLNWTEPEAPNGLISQYHVIYQERPDEAAPGSSTVHAFTVK 4009
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
+ + F + V A N GKV+S + N + E
Sbjct 4010 GSSRQAHLFGLEPFTTYHIGVAAVNRAGKVSSPWTLIKTLESAPSGL-MNFTAEQREG-G 4067
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
L L W+ P + +I YN+ +S PE + F + L PFT Y+
Sbjct 4068 RALLLQWSEPVRTNGVIKAYNV---------FSDGLPEY-SGLGRQFLFRRLAPFTLYIL 4117
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRP-SKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
+ G + S + T E P S+ ++P+ +V+L W P
Sbjct 4118 TLEACTAAGCAH----SVPQTLWTEEAPPDSQMAPTIQSVEPT------SVRLHWSQ--P 4165
Query 357 FEANGKILDYEVTLTRWKSHLQ----NYTVNATKLTVNLTNDR--------------YLA 398
NGKI+ YEV R + T T T Y
Sbjct 4166 ANPNGKIIRYEVIRRRLQGEDWGNRTVQADENTVFTEYNTEGNGWVCTDTGLQPWGLYSY 4225
Query 399 TLTVRNLVGK--SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
+ N G S +V+ P L + W PR I
Sbjct 4226 RICTWNSAGHTCSSWSVVRTSQAPPDGLSPPEVSYVSTSPLQLLISWFAPRH-TNGVIQS 4284
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ + + + + +Y G L Y V G + E +
Sbjct 4285 YRLQRNGVFAAASFN----SSTFSYTDGQLLPFTTYSYAVLACTGGGCCTSEPTNITTPE 4340
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
A P+ +G ++ + W P V NG I Y + G E ++
Sbjct 4341 ASPAGVSPPVLWAIGAHQINVSWS--PPSVPNGKIAKYLLH---CDGEE---HLAGQDLS 4392
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDG 603
LS+L T Y V + A T G
Sbjct 4393 LLLSNLRPFTQYNVSLVACTKGGCTAS 4419
Score = 156 bits (393), Expect = 3e-37, Method: Composition-based stats.
Identities = 98/525 (19%), Positives = 162/525 (31%), Gaps = 54/525 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCT 183
PPE + V + + W R H + ++ L+ + A
Sbjct 4430 PPEDMDPPTLHVMGPESIEITWAPPRNPHGQIRSYELRRDGAIVYIGLETR--------Y 4481
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV-INSEELSSILKL 242
D+ V V A N+ G V S + + P+ P L + L +
Sbjct 4482 HDFILTPGVQYGYTVTATNSRGSVLSPLVK----GQTSPSAPSGLQPPKLRAGEALELLV 4537
Query 243 TWTNPSIKSVIILKYNIQYRT--KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
W P + I Y + R + I ++ S V+ LKPF Y R++
Sbjct 4538 NWNPPVRTNGKITNYTLFIRELLEGEIRTMCINTTHSSFGTRSLAVKHLKPFHRYEVRVQ 4597
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
G S+W+ T E P P+ ++ + V + W P + +
Sbjct 4598 ACTALGC-TSSEWTP---TQTSEIPPLLQPAPHLEVQTAAGGFQPIVAVWWAG--PLQPH 4651
Query 361 GKILDYEVTLTR---WKSHLQNYTVNATKLTV-----NLTNDRYLATLTVRNLVGKSDAA 412
GKI+ +E+ + W + L+ L Y + N GK +
Sbjct 4652 GKIVRFELYRRQTASWPGTSSPLLIYNGSLSSFTDRELLPFTEYEYQVWAVNSAGKVASN 4711
Query 413 VLTIPACDFQATHPVMDLKA----FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCIT 468
P LKA V + P + L T
Sbjct 4712 W----TWCRTGPAPPEGLKAPTFHTVSSTQAVVNISAPSKPNGNISL---FRVFSNSSGT 4764
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-ESIKAYLKQAPPSKGPTVRT 527
+G + L L Y I V S + + APPS +
Sbjct 4765 HVMLSEGMATQQTLHD-LRPFTTYAIGVEACTCFNCCSRGPTAELRTHPAPPSGLSPPQV 4823
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE---------YT 578
+ +G A +W P + NG I +Y + ++A + S TE +
Sbjct 4824 QTLGSRMASFQW--APPQLPNGVIHSYELQLHRACPPDSAPHCPPSPTERKYWGPGHRAS 4881
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
L+ L +T Y V++ A+ + G +F T K V
Sbjct 4882 LAGLQPNTAYGVQVVAHNEAGSTASGWTSFRTKKEMPQYQALFSV 4926
Score = 153 bits (385), Expect = 3e-36, Method: Composition-based stats.
Identities = 79/463 (17%), Positives = 156/463 (34%), Gaps = 36/463 (8%)
Query 171 DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
D + F V A + G V+SD + + P
Sbjct 1892 DSILVYRGSRQSVYESGLQPFTEYLYRVTASHKGGSVSSDWSRGRTLGSAPHSVPTPSRA 1951
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQ--IPPEDTASTRSSFTVQD 288
+ S +++ W P++ ++ KY ++ ++D++ E + + +
Sbjct 1952 QSINGYS--VEVAWNEPAMVKGVLEKYILKAYSEDSAQPHMPSASTEFNNTDIRTGILTG 2009
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
L PF Y + G ++ S S T ++ P + P ++
Sbjct 2010 LHPFHSYAVTLTACSRAGC---TESSRALSISTPQEAPQE------VQAPVAEALPNSLS 2060
Query 349 LVWKTLPPFEANGKILDYEVTLTR---WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNL 405
W PP +ANG I Y + + + QNYTV ++ Y T+
Sbjct 2061 FFWS--PPRQANGIITQYSLYMDGRLVYTGKGQNYTVTDLRVF-----TAYEITVGACTR 2113
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR---ESVKKYILEWCVLSD 462
G ++++ + + + A + ++W PR +++YIL + +
Sbjct 2114 AGCTNSSRVILHTAQLPPERVDPPVLAILDSRTVHIQWKQPRQLNGILERYIL-YTLNPT 2172
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+ D +T+L +L+ YLI + G + E +A + + P
Sbjct 2173 HNSTVWDVVYNSTENLQTHLLYHLSPGCLYLIKLGACTGGGCTTSEPSQALMDETVPEGV 2232
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
P R + + W + NG I Y ++ + + +SS
Sbjct 2233 PAPRAHSHSPDSFNISWTE--PGHPNGVITTYELYL------DGTLIHNSSELSCHAYGF 2284
Query 583 TSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ-GEIEAIVVP 624
+L+ ++ A T +G GP T + G + V P
Sbjct 2285 DPGSLHTFQVQACTAKGCALGPLVENRTLEAPPEGTVNLFVKP 2327
Score = 141 bits (354), Expect = 2e-32, Method: Composition-based stats.
Identities = 75/382 (20%), Positives = 129/382 (34%), Gaps = 35/382 (9%)
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
SF DL+P T Y +R+ G+G+ S+ T ED P + +
Sbjct 3443 DENTRSFIDTDLEPSTVYEYRVSVWNSYGRGF----SQSVRASTREDVPQGVTAPRWART 3498
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL 397
+H + L WK P ++NG I Y + L + Q ++ T Y
Sbjct 3499 GNHED---VIFLTWKE--PTQSNGPITHYIL-LRDGRERFQGAALSFTDTQGIQPLQEYS 3552
Query 398 ATLTVRNLVGKSDA-AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
L G +D+ V+ + P ++ A + L + W+ P + I E
Sbjct 3553 YQLKACTAAGCADSCKVVATATRGVLESVPPPNITAQSPET-LHLSWSVPEKR-NDAIKE 3610
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ + D I D R + L Y T++ + G S E Q
Sbjct 3611 YQLWLDGKGLIYT----DTNDRRQHTVTGLQPHTNYSFTLSACTSVGCTSSEPSVGQTLQ 3666
Query 517 APPSKG-PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS-SH 574
A P T R + L W+ P + NG I Y + N + + V
Sbjct 3667 AAPQGVWVTPRHIIINSTTVELYWN--PPERPNGVISQYRL-----RRNGSLLLVGGRDD 3719
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTL 634
+T +L ++ Y+ + A T G E+ P + ++ P C +
Sbjct 3720 QSFTDKNLEPNSRYIYTLEARTGGGSSLSEEYLVQMPMWTPEDVH----PPCN-VTVLGS 3774
Query 635 LGVLFCFNKRDLIKKHIWPNVP 656
+ + ++ P +P
Sbjct 3775 DSIFVAWPAPGILL----PKIP 3792
Score = 140 bits (353), Expect = 2e-32, Method: Composition-based stats.
Identities = 82/522 (16%), Positives = 155/522 (30%), Gaps = 46/522 (9%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGR-ETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
G P P + K+ W L N T++ + +
Sbjct 2609 GTPEGIPG-PELLPYTPTKIIVSWQPPTHLDGLVENITIERRVKEQEEVRSLVILPRSQA 2667
Query 182 CTV---DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL-S 237
D + + + E V G S +P+ P + L
Sbjct 2668 VRFIDNDPALRPWTHYEYRVLGSTLNGGTNSSAW---VEVTTRPSRPSGVQPPTVHVLGP 2724
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+++TW P I++ I+ Y I+ I + S S V+ L PFT Y
Sbjct 2725 DAVEVTWKAPLIRNGDIVSYEIR------MPDPLIEITNVTSFVLSHLVKHLIPFTNYSV 2778
Query 298 RIRCMKEDGKGYW--SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
I G GY S T+ P + + G V + W+ P
Sbjct 2779 SIVAC-SGGHGYLGGCTESLPTFATTHPALPQELTPLSISL-----LGQSYVGISWQ--P 2830
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN--------------DRYLATLT 401
P + NG L YE+ + + L + L N+ + Y L
Sbjct 2831 PSKPNGPNLRYELLRRKIQQPLASNPPEDLNLWHNIYSGTRRFYEDKGLSRFTTYEYKLF 2890
Query 402 VRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
V N +G + + +T+ + + V W P + +E+ L
Sbjct 2891 VHNSLGFTPSQEVTVTTLAGSPERGATVTASILNHTAIDVRWKRPTFQDLQGDVEYYTLF 2950
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
+ + + V ++ G+LA + Y + + + ++ + P
Sbjct 2951 WSSGTSVESLKIFPDV-DFHVIGHLAPNVEYQVFLLVFNGVHAINSTVVRVTTWEEEPRG 3009
Query 522 GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS 581
+ + W N I +++ NE + +TL
Sbjct 3010 MRPPEVVIINSTAVRVIW--TSPSNPNAVITESSVY----ANNELHKAGAGAPGSFTLED 3063
Query 582 LTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
L+ T+Y +++ T + +T + I ++
Sbjct 3064 LSPFTIYDIQVEVCTKDACVKSSGTQVSTAEDTPSGISIPII 3105
Score = 140 bits (352), Expect = 3e-32, Method: Composition-based stats.
Identities = 87/540 (16%), Positives = 162/540 (30%), Gaps = 61/540 (11%)
Query 120 IISGLPPEKPKNLSCIVNE--GKKMRCEWDGGRE-THLETNFTLKSEWATHKFADCKAKR 176
+ P E P+ + V E + W R+ + T ++L + D +
Sbjct 2035 LSISTPQEAPQEVQAPVAEALPNSLSFFWSPPRQANGIITQYSL--------YMDGRLVY 2086
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP---NPPHNLSVINS 233
F E+ V A G S + ++ P +PP L++++
Sbjct 2087 TGKGQNYTVTDLRVFTAYEITVGACTRAGCTNSSRVILH-TAQLPPERVDPPV-LAILD- 2143
Query 234 EELSSILKLTWTNPSIKSVIILKYNI-QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
S + + W P + I+ +Y + ST + T + ++ L P
Sbjct 2144 ---SRTVHIQWKQPRQLNGILERYILYTLNPTHNSTVWDVVYNSTENLQTHLLYH-LSPG 2199
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
Y+ ++ G SE + + E P P+ +H+ + + W
Sbjct 2200 CLYLIKLGACTGGGCTT----SEPSQALMDETVPEGVPAPR-----AHSHSPDSFNISWT 2250
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL----TNDRYLATLTVRNLVGK 408
P NG I YE+ L H N+++L+ + + + G
Sbjct 2251 E--PGHPNGVITTYELYLDGTLIH------NSSELSCHAYGFDPGSLHTFQVQACTAKGC 2302
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL------SD 462
+ ++ + V V W P L + VL +D
Sbjct 2303 ALGPLVENRTLEAPPEGTVNLFVKPEGSREAAVRWDAPPHP--NGRLTYSVLITGNFYAD 2360
Query 463 KAPCITDWQQEDGTVHRTY------LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+A TVH + L L Y + V + G + + +
Sbjct 2361 QAGDNYTLLSSTKTVHSSKGDRLWVLVDRLVPCSNYTVQVNASNSQGSVLSDRVSVEMPP 2420
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSS 573
P + R + W + G R Y + R + S+
Sbjct 2421 GAPDGLLSPRLAAATPTSLQVVWSTPARNNAPGSPR-YQLQMRPDPSTRGLLELFPIPSA 2479
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTT 633
Y ++ L T+Y R+ A G T + G ++A V+ V +
Sbjct 2480 LLSYEVTGLQPFTVYEFRLVATNGFGSAYSDWTPLMTTEDKPGPMDAPVLNVKAGMMSVA 2539
Score = 136 bits (343), Expect = 4e-31, Method: Composition-based stats.
Identities = 81/489 (17%), Positives = 155/489 (32%), Gaps = 42/489 (9%)
Query 142 MRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAE 201
M W + T T + + + T+CTV + + +EA
Sbjct 2536 MSVAWR--KPTECNGAITHYNIYQHGRLYLTV--SGGVTNCTVVHLRP-HTAYQFQIEAC 2590
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNL-SVINSEELSSILKLTWTNPSIKSVIILKYNIQ 260
++ G S P P + + + ++W P+ ++ I+
Sbjct 2591 SSKGCSMSPA---SETVWTLPGTPEGIPGPELLPYTPTKIIVSWQPPTHLDGLVENITIE 2647
Query 261 YRTKDASTWSQIPPEDTASTRSSFTVQD--LKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
R K+ + S F D L+P+T Y +R+ +G S W E
Sbjct 2648 RRVKEQEEVRSL-VILPRSQAVRFIDNDPALRPWTHYEYRVLGSTLNGGTNSSAWVE--- 2703
Query 319 GITYEDRPSK-APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL 377
T RPS P + + P V++ WK P NG I+ YE+ + +
Sbjct 2704 VTTRPSRPSGVQPPTVHVLGPD------AVEVTWKA--PLIRNGDIVSYEIRMPDPLIEI 2755
Query 378 QNYT--VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK 435
N T V + + + Y ++ G T F THP + + P
Sbjct 2756 TNVTSFVLSHLVKHLIPFTNYSVSIVA-CSGGHGYLGGCTESLPTFATTHPALPQELTPL 2814
Query 436 D------NMLWVEWTTPRES--------VKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
+ + + W P + + + ++ + S+ + W R Y
Sbjct 2815 SISLLGQSYVGISWQPPSKPNGPNLRYELLRRKIQQPLASNPPEDLNLWHNIYSGTRRFY 2874
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
L+ Y + + G + + P +G TV + + W +
Sbjct 2875 EDKGLSRFTTYEYKLFVHNSLGFTPSQEVTVTTLAGSPERGATVTASILNHTAIDVRWKR 2934
Query 542 LPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
G + YT+F+ + E ++ + + + L + Y V + +
Sbjct 2935 PTFQDLQGDVEYYTLFWSSGTSVE-SLKIFPDVDFHVIGHLAPNVEYQVFLLVFNGVHAI 2993
Query 602 DGPEFTFTT 610
+ TT
Sbjct 2994 NSTVVRVTT 3002
Score = 136 bits (341), Expect = 6e-31, Method: Composition-based stats.
Identities = 81/465 (17%), Positives = 149/465 (32%), Gaps = 63/465 (14%)
Query 135 IVNEGKKMRCEWDGGR-ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN 193
V + W +TL + + + T +D S
Sbjct 1059 RVQSSSAINLSWSPPDFPNAHWLTYTLFRDD--SEIYTTDDQHPYYTQYFLDTSLSPHTA 1116
Query 194 IEVWVEAENALGKVTSDHINFDPVYKVKP-NPPHNLSVINS-EELSSILKLTWTNPSIKS 251
++E N V S + +YK KP +L++ + S + L WT S S
Sbjct 1117 YSYYIETSN----VHSSTRSIPVIYKTKPEGSEGHLNLTHIIPVASDSITLVWTGLSNHS 1172
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
I KY + D + P +S T+++L PFT+Y F ++ Y
Sbjct 1173 GPIEKYVLSCTPVDHTE----PCVSYEGPETSATIRNLVPFTQYCFSVQGCTNGSCLY-- 1226
Query 312 DWSEEASGITYEDRPSKA-PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S + T + P + P +KI P+ +++ W P ++NG I+ YE+ +
Sbjct 1227 --SSPITVTTAQAPPQRQEPPTVWKISPT------ELKVEWS--RPVDSNGVIIRYELYM 1276
Query 371 TRWKSHLQN--------------------------YTVNATKLTVNLTNDRYLATLTVRN 404
RW S ++ +T L+ + Y + N
Sbjct 1277 KRWPSTEESLVFESHGWFHSHPASPSANQSENVLQDPQVSTVLSGLDPHTEYAFRVLAVN 1336
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES-VKKYILEWCVLSDK 463
+ G +A + + + L V W P E+ + I+ + +
Sbjct 1337 MAGSVSSAWASERTGESAPVFMAAPSVSPLSPYSLSVSWEKPAENFTRGEIIGYKISMVS 1396
Query 464 APCI--------TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
+ + ++Y+ L + Y TV+ + G + +
Sbjct 1397 ERSPQRDVPVMCSKLVHFAESQDQSYIVQRLKPYRTYSFTVSLCASVGCVTSALGEGQTL 1456
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
A P++ + V + W LP NG Y + R
Sbjct 1457 AAAPAQLRSPMVTGVTSTTVHIRW--LPPAEVNGPPPLYRLERRE 1499
Score = 136 bits (341), Expect = 6e-31, Method: Composition-based stats.
Identities = 73/446 (16%), Positives = 125/446 (28%), Gaps = 58/446 (13%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP V + SS + L+W+ P + L Y + +D S + T+
Sbjct 1054 PPPRGRV----QSSSAINLSWSPPDFPNAHWLTYTLF---RDDSEIYTTDDQHPYYTQY- 1105
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
F L P T Y + I S S T + + + I +
Sbjct 1106 FLDTSLSPHTAYSYYIETSNVHS----STRSIPVIYKTKPEGSEGHLNLTHIIPVASD-- 1159
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN----DRYLAT 399
++ LVW L +G I Y ++ T + + + + N +Y +
Sbjct 1160 --SITLVWTGL--SNHSGPIEKYVLSCTPVDHTEPCVSYEGPETSATIRNLVPFTQYCFS 1215
Query 400 LTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES---VKKYI 454
+ S +T Q P K P L VEW+ P +S + +Y
Sbjct 1216 VQGCTNGSCLYSSPITVTTAQAPPQRQEPPTVWKISP--TELKVEWSRPVDSNGVIIRYE 1273
Query 455 L-----------------EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
L W +P + + + L Y V
Sbjct 1274 LYMKRWPSTEESLVFESHGWFHSHPASPSANQSENVLQDPQVSTVLSGLDPHTEYAFRVL 1333
Query 498 PVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
V G S ++ P + + W++ + G I Y I
Sbjct 1334 AVNMAGSVSSAWASERTGESAPVFMAAPSVSPLSPYSLSVSWEKPAENFTRGEIIGYKIS 1393
Query 558 YRTIIGNETAVNV---------DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
+ + V V +S Y + L Y ++ G
Sbjct 1394 MVSERSPQRDVPVMCSKLVHFAESQDQSYIVQRLKPYRTYSFTVSLCASVGCVTSALGEG 1453
Query 609 TTPKFAQGEIEAIVVPVCLAFLLTTL 634
T A ++ P+ TT+
Sbjct 1454 QTLAAAPAQLR---SPMVTGVTSTTV 1476
Score = 131 bits (329), Expect = 2e-29, Method: Composition-based stats.
Identities = 99/607 (16%), Positives = 171/607 (28%), Gaps = 73/607 (12%)
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD-GGRET 152
++T + G T+ P P G + W+
Sbjct 1912 FTEYLYRVTASHKGGSVSSDWSRGRTL-GSAPHSVPTPSRAQSINGYSVEVAWNEPAMVK 1970
Query 153 HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY----FVNIEVWVEAENALGKVT 208
+ + LK+ + + + + F + V + A + G
Sbjct 1971 GVLEKYILKAYSEDSAQPHMPSASTEFNNTDIRTGILTGLHPFHSYAVTLTACSRAGCTE 2030
Query 209 SDHINFDPVYKVKP-NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS 267
S + P P + +E L + L W+ P + II +Y++
Sbjct 2031 SS----RALSISTPQEAPQEVQAPVAEALPNSLSFFWSPPRQANGIITQYSL-------- 2078
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
++TV DL+ FT Y + G S T + P
Sbjct 2079 --YMDGRLVYTGKGQNYTVTDLRVFTAYEITVGACTRAG----CTNSSRVILHTAQLPPE 2132
Query 328 KA-PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV---- 382
+ P +D RTV + WK P + NG + Y + + + V
Sbjct 2133 RVDPPVLAILD------SRTVHIQWKQ--PRQLNGILERYILYTLNPTHNSTVWDVVYNS 2184
Query 383 ---NATKLTVNL-TNDRYLATLTVRNLVG-KSDAAVLTIPACDFQATHPVMDLKAFPKDN 437
T L +L YL L G + + P + D+
Sbjct 2185 TENLQTHLLYHLSPGCLYLIKLGACTGGGCTTSEPSQALMDETVPEGVPAPRAHSHSPDS 2244
Query 438 MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
+ WT P I + + D T Y + V
Sbjct 2245 -FNISWTEP-GHPNGVITTYELYLDG----TLIHNSSELSCHAY---GFDPGSLHTFQVQ 2295
Query 498 PVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
A G ++ +APP + K G EA + WD P NG + Y++
Sbjct 2296 ACTAKGCALGPLVENRTLEAPPEGTVNLFVKPEGSREAAVRWDAPP--HPNGRLT-YSVL 2352
Query 558 -------------YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
Y + +T + + L + Y V++ A +G
Sbjct 2353 ITGNFYADQAGDNYTLLSSTKTVHSSKGDRLWVLVDRLVPCSNYTVQVNASNSQGSVLSD 2412
Query 605 EFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLF--CFNKRDLIKKHIWPNVPDPSKSH 662
+ P G + ++ P A T+L V N ++ PDPS
Sbjct 2413 RVSVEMP---PGAPDGLLSPRLAAATPTSLQVVWSTPARNNAPGSPRYQLQMRPDPSTRG 2469
Query 663 IAQWSPH 669
+ + P
Sbjct 2470 LLELFPI 2476
Score = 129 bits (324), Expect = 6e-29, Method: Composition-based stats.
Identities = 82/506 (16%), Positives = 149/506 (29%), Gaps = 46/506 (9%)
Query 138 EGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
C G L +E + D T +D E
Sbjct 3407 NATTHICTVSRGP---LNPIGKETAEGLCSTAEEIVHSGDENTRSFIDTDLEPSTVYEYR 3463
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSV---INSEELSSILKLTWTNPSIKSVII 254
V N+ G+ S + V P ++ + ++ LTW P+ + I
Sbjct 3464 VSVWNSYGRGFSQSVRASTREDV----PQGVTAPRWARTGNHEDVIFLTWKEPTQSNGPI 3519
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
Y + +D Q T+ ++P EY ++++ G
Sbjct 3520 THYIL---LRDGRERFQGAALSFTDTQ------GIQPLQEYSYQLKACTAAGCADSCKVV 3570
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL-TRW 373
A+ E P P+ Q T+ L W P + N I +Y++ L +
Sbjct 3571 ATATRGVLESVP--PPNI-------TAQSPETLHLSWSV--PEKRNDAIKEYQLWLDGKG 3619
Query 374 KSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG-KSDAAVLTIPACDFQATHPVMDLKA 432
+ +T + Y TL+ VG S + V
Sbjct 3620 LIYTDTNDRRQHTVTGLQPHTNYSFTLSACTSVGCTSSEPSVGQTLQAAPQGVWVTPRHI 3679
Query 433 FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
+ + W P E I ++ + + + + G +++ NL + Y
Sbjct 3680 IINSTTVELYWNPP-ERPNGVISQYRLRRNGSLLL-----VGGRDDQSFTDKNLEPNSRY 3733
Query 493 LITVTPVYADGPGSPESIKAYLK-QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
+ T+ G E + P P +G + + W + + +
Sbjct 3734 IYTLEARTGGGSSLSEEYLVQMPMWTPEDVHPPCNVTVLGSDSIFVAWPAPGILLPKIPV 3793
Query 552 RNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP 611
Y+I +V + Y L +L T Y +R+ A EG P T
Sbjct 3794 -EYSILLSGGNMMLLTFSVGLRQSAY-LKNLAPFTQYEIRIQAC-QEGCGVSPGTHVRTL 3850
Query 612 KFAQGEIEAIVVPVCLAFLLTTLLGV 637
+ A ++P L L + + V
Sbjct 3851 EAAP----VGLMPPLLKALGSHCIEV 3872
Score = 126 bits (315), Expect = 7e-28, Method: Composition-based stats.
Identities = 78/588 (13%), Positives = 160/588 (27%), Gaps = 57/588 (10%)
Query 69 TNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEK 128
+++T+ T+ + + + + + +V + +PP
Sbjct 2363 GDNYTLLSSTKTVHSSKGDRLWVLVDRLVPCSNYTVQVNASNSQGSVLSDRVSVEMPPGA 2422
Query 129 PKNL---SCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCT 183
P L ++ W + + L+ + +
Sbjct 2423 PDGLLSPRLAAATPTSLQVVWSTPARNNAPGSPRYQLQMRPDPSTRGLLELFPIPSALLS 2482
Query 184 VDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
+ + F E + A N G SD KP P + + ++ +
Sbjct 2483 YEVTGLQPFTVYEFRLVATNGFGSAYSDWTPLMTTED-KPGP---MDAPVLNVKAGMMSV 2538
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
W P+ + I YNI + ++ TV L+P T Y F+I
Sbjct 2539 AWRKPTECNGAITHYNI--------YQHGRLYLTVSGGVTNCTVVHLRPHTAYQFQIEAC 2590
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAP-SFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
G S SE T P P P+ + + W+ +
Sbjct 2591 SSKGCSM-SPASETVW--TLPGTPEGIPGPELLPYTPTK------IIVSWQPPTHLDGLV 2641
Query 362 KILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR-------YLATLTVRN-LVGKSDAAV 413
+ + E + + + ++ + ND Y + G + +A
Sbjct 2642 ENITIERRVKEQEEVRSLVILPRSQAVRFIDNDPALRPWTHYEYRVLGSTLNGGTNSSAW 2701
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQE 473
+ + + + + + V W P I+ + + + +
Sbjct 2702 VEVTTRPSRPSGVQPPTVHVLGPDAVEVTWKAPLIR-NGDIVSYEIRMPD--PLIEITNV 2758
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYA-----DGPGSPESIKAYLKQAPPSKGPTVRTK 528
V +L +L Y +++ G A A P + +
Sbjct 2759 TSFVLS-HLVKHLIPFTNYSVSIVACSGGHGYLGGCTESLPTFATTHPALPQELTPLSIS 2817
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG----------NETAVNVDSSHTEYT 578
+G++ + W P NG Y + R I N + Y
Sbjct 2818 LLGQSYVGISWQ--PPSKPNGPNLRYELLRRKIQQPLASNPPEDLNLWHNIYSGTRRFYE 2875
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVC 626
L+ T Y ++ + G E T TT + + +
Sbjct 2876 DKGLSRFTTYEYKLFVHNSLGFTPSQEVTVTTLAGSPERGATVTASIL 2923
Score = 119 bits (298), Expect = 8e-26, Method: Composition-based stats.
Identities = 77/508 (15%), Positives = 151/508 (30%), Gaps = 63/508 (12%)
Query 87 SSVTFTDIASLNIQLTCNIL-TFGQLEQNVYGITIISGLP----------PEKPKNL--- 132
S V ++ L + E V G T+ G P +P +
Sbjct 2658 SLVILPRSQAVRFIDNDPALRPWTHYEYRVLGSTLNGGTNSSAWVEVTTRPSRPSGVQPP 2717
Query 133 SCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF 191
+ V + W + + ++ ++ + + + + + F
Sbjct 2718 TVHVLGPDAVEVTWKAPLIRNGDIVSYEIRMPDPLIEITNVTS----FVLSHLVKHLIPF 2773
Query 192 VNIEVWVEAENA----LGKVTSDHINFDPVYKVKP--NPPHNLSVINSEELSSILKLTWT 245
N V + A + LG T F + P P ++S++ S + ++W
Sbjct 2774 TNYSVSIVACSGGHGYLGGCTESLPTFATTHPALPQELTPLSISLLGQ----SYVGISWQ 2829
Query 246 NPSIKSVIILKYNIQYR----------TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
PS + L+Y + R +D + W I + TR + + L FT Y
Sbjct 2830 PPSKPNGPNLRYELLRRKIQQPLASNPPEDLNLWHNIY----SGTRRFYEDKGLSRFTTY 2885
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
+++ G S+E + T P + + + + + WK
Sbjct 2886 EYKLFVHNSLGF----TPSQEVTVTTLAGSPERG-----ATVTASILNHTAIDVRWKRPT 2936
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV---NLTNDRYLATLTVRNLVGKSDAA 412
+ G + Y + + S V N Y L V N V ++
Sbjct 2937 FQDLQGDVEYYTLFWSSGTSVESLKIFPDVDFHVIGHLAPNVEYQVFLLVFNGVHAINST 2996
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQ 472
V+ + + + + V WT+P I E V ++ +
Sbjct 2997 VVRVTTWEEEPRGMRPPEVVIINSTAVRVIWTSPSNP-NAVITESSVYANNEL-----HK 3050
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGK 532
++ +L+ Y I V D + + PS + +
Sbjct 3051 AGAGAPGSFTLEDLSPFTIYDIQVEVCTKDACVKSSGTQVSTAEDTPSGISIPIIRDITS 3110
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
++W NG I Y + +T
Sbjct 3111 RSLQIDW--TAPGNPNGIILGYDVLRKT 3136
Score = 115 bits (288), Expect = 1e-24, Method: Composition-based stats.
Identities = 94/510 (18%), Positives = 158/510 (31%), Gaps = 63/510 (12%)
Query 126 PEKPKNL---SCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHK-----FADCKAKR 176
P P L E ++ W+ T+ + TN+TL +
Sbjct 4516 PSAPSGLQPPKLRAGEALELLVNWNPPVRTNGKITNYTLFIRELLEGEIRTMCINTTHSS 4575
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHN-LSV-INSE 234
S V + + EV V+A ALG +S+ P L V +
Sbjct 4576 FGTRSLAVKHLKPFH-RYEVRVQACTALGCTSSEWTPTQTSEIPPLLQPAPHLEVQTAAG 4634
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA-STRSSFTVQDLKPFT 293
I+ + W P I+++ + YR + AS P + SSFT ++L PFT
Sbjct 4635 GFQPIVAVWWAGPLQPHGKIVRFEL-YRRQTASWPGTSSPLLIYNGSLSSFTDRELLPFT 4693
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS--KAPSFWYKIDPSHTQGYRTVQLVW 351
EY +++ + GK S T P KAP+F S TQ +
Sbjct 4694 EYEYQVWAVNSAGK----VASNWTWCRTGPAPPEGLKAPTF---HTVSSTQAVVNIS--- 4743
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTV---RNLV 406
P + NG I + V +H+ AT+ T++ Y + N
Sbjct 4744 ---APSKPNGNISLFRVFSNSSGTHVMLSEGMATQQTLHDLRPFTTYAIGVEACTCFNCC 4800
Query 407 GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
+ A L P M +W P+ + ++ L C
Sbjct 4801 SRGPTAELRTHPAPPSGLSPPQVQTL--GSRMASFQWAPPQ--LPNGVIHSYELQLHRAC 4856
Query 467 ITDWQQE-DGTVHRTYLRG--------NLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
D + G L + Y + V G + K+
Sbjct 4857 PPDSAPHCPPSPTERKYWGPGHRASLAGLQPNTAYGVQVVAHNEAGSTASGWTSFRTKKE 4916
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI---FYRTIIGNETAVNVDSSH 574
P + + + + ++W V NG ++ Y + R G +T + + +
Sbjct 4917 MP-QYQALFSVDSNASTVWVDWSGT--FVLNGQLKEYVVTDGGRRVYSGLDTTLYIPRT- 4972
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
D + ++ TD G P
Sbjct 4973 ---------VDKTFFFQVTCTTDIGSVKTP 4993
Score = 69.1 bits (167), Expect = 2e-10, Method: Composition-based stats.
Identities = 36/232 (16%), Positives = 66/232 (28%), Gaps = 9/232 (4%)
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD 462
+ G S V + AC + + + + W+ P + + L + + D
Sbjct 1030 TCVPGASHLDVNNLLACSKTPSQQPPPRGRVQSSSAINLSWSPP-DFPNAHWLTYTLFRD 1088
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+ T Q L +L+ Y + + K
Sbjct 1089 DSEIYTTDDQHPYYTQYF-LDTSLSPHTAYSYYIETSNVHSSTRSIPVIYKTKPEGSEGH 1147
Query 523 PTVR-TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS 581
+ V + L W L +G I Y + + E V+ + T T+ +
Sbjct 1148 LNLTHIIPVASDSITLVWTGL--SNHSGPIEKYVLSCTPVDHTEPCVSYEGPETSATIRN 1205
Query 582 LTSDTLYMVRMAAYTDEGGKDGPEFTFTT----PKFAQGEIEAIVVPVCLAF 629
L T Y + T+ T TT P+ + + P L
Sbjct 1206 LVPFTQYCFSVQGCTNGSCLYSSPITVTTAQAPPQRQEPPTVWKISPTELKV 1257
Score = 67.6 bits (163), Expect = 5e-10, Method: Composition-based stats.
Identities = 55/288 (19%), Positives = 99/288 (34%), Gaps = 34/288 (12%)
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
+ + +L + Q V T+ PE+ ++ + + W
Sbjct 2879 LSRFTTYEYKLFVHNSLGFTPSQEVTVTTLAGS--PERGATVTASILNHTAIDVRWKRPT 2936
Query 151 ETHLET---NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV 207
L+ +TL W++ + K V V +V++ N + +
Sbjct 2937 FQDLQGDVEYYTLF--WSSGTSVES-LKIFPDVDFHVIGHLAPNVEYQVFLLVFNGVHAI 2993
Query 208 TSDHINFDPVYKVKPN--PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD 265
S + + PP + + S+ +++ WT+PS + +I T+
Sbjct 2994 NSTVVRVTTWEEEPRGMRPPEVVII-----NSTAVRVIWTSPSNPNAVI--------TES 3040
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
+ + + A SFT++DL PFT Y ++ +D S T ED
Sbjct 3041 SVYANNELHKAGAGAPGSFTLEDLSPFTIYDIQVEVCTKDACVK----SSGTQVSTAEDT 3096
Query 326 PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
PS I R++Q+ W P NG IL Y+V W
Sbjct 3097 PSG-----ISIPIIRDITSRSLQIDWTA--PGNPNGIILGYDVLRKTW 3137
Score = 42.5 bits (98), Expect = 0.022, Method: Composition-based stats.
Identities = 24/121 (20%), Positives = 40/121 (33%), Gaps = 4/121 (3%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
PS+ P R + + L W P D N YT+F T +
Sbjct 1050 PSQQPPPRGRVQSSSAINLSWS--PPDFPNAHWLTYTLFRDDSEIYTTDDQHPYYTQYFL 1107
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDG-PEFTFTTPKFAQGEIEAI-VVPVCLAFLLTTLLG 636
+SL+ T Y + P T P+ ++G + ++PV + G
Sbjct 1108 DTSLSPHTAYSYYIETSNVHSSTRSIPVIYKTKPEGSEGHLNLTHIIPVASDSITLVWTG 1167
Query 637 V 637
+
Sbjct 1168 L 1168
Score = 38.7 bits (88), Expect = 0.41, Method: Composition-based stats.
Identities = 40/256 (16%), Positives = 77/256 (30%), Gaps = 32/256 (13%)
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR-NYTIFYRTIIGNETAVN 569
+ +K+ ++G V V + Q+G + + T+ GN++ +
Sbjct 1848 RGCVKEVAFTRGAVVNLASVSSRAVRVN--------QDGCLSSDSTV---NCGGNDSILV 1896
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAF 629
S S L T Y+ R+ A G T A + P
Sbjct 1897 YRGSRQSVYESGLQPFTEYLYRVTASHKGGSVSSDWSRGRTLGSAPHSV-----PTPSRA 1951
Query 630 LLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQ-----MYS 684
V +N+ ++K + + AQ PH P + +
Sbjct 1952 QSINGYSVEVAWNEPAMVKGVLEKYILKAYSEDSAQ--PHMPSASTEFNNTDIRTGILTG 2009
Query 685 DGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSS 744
F + V + A + E ++L + ++ E + + + P+ S
Sbjct 2010 LHPFHSYA-VTLTACSRAGCTESSRALSISTPQEAPQEVQAPV-------AEALPNSLSF 2061
Query 745 DENESSQNTSSTVQYS 760
+ Q QYS
Sbjct 2062 FWSPPRQANGIITQYS 2077
>sp|P11627|L1CAM_MOUSE Neural cell adhesion molecule L1 OS=Mus
musculus OX=10090 GN=L1cam PE=1 SV=1
Length=1260
Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats.
Identities = 78/408 (19%), Positives = 136/408 (33%), Gaps = 29/408 (7%)
Query 215 DPVYKVKPNPPHNLSVINSEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
+ P P +L + + L S + L+W+ + I KY+I++ K+ +
Sbjct 604 QLLVVGSPGPVPHLELSDRHLLKQSQVHLSWSPAEDHNSPIEKYDIEFEDKEMAPEKWFS 663
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
++S T+ L P+ Y FR+ + + G G S SE S +T E P K P
Sbjct 664 LGKVPGNQTSTTL-KLSPYVHYTFRVTAINKYGPGEPSPVSE--SVVTPEAAPEKNPVDV 720
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR--WKSHLQNYTVNATKLTVNL 391
+ + WK L + N + Y V + + TV+ L V+
Sbjct 721 RG----EGNETNNMVITWKPLRWMDWNAPQIQYRVQWRPQGKQETWRKQTVSDPFLVVSN 776
Query 392 TND--RYLATLTVRNLVGKSDAAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTP- 446
T+ Y + N GK +TI D+ P ++ + + V W
Sbjct 777 TSTFVPYEIKVQAVNNQGKGPEPQVTIGYSGEDYPQVSPELEDITIFNSSTVLVRWRPVD 836
Query 447 ----RESVKKY-ILEWCVLSDKAPCITDWQQ---EDGTVHRTYLRGNLAESKCYLITVTP 498
+ +K Y + W S + + + + L Y + V
Sbjct 837 LAQVKGHLKGYNVTYWWKGSQRKHSKRHIHKSHIVVPANTTSAILSGLRPYSSYHVEVQA 896
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
G G + P + + +L W P NG + Y + Y
Sbjct 897 FNGRGLGPASEWTFSTPEGVPGHPEALHLECQSDTSLLLHWQ--PPLSHNGVLTGYLLSY 954
Query 559 RTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ G D + L++L D Y ++ A T +GG
Sbjct 955 HPVEGESKEQLFFNLSDPELRTHNLTNLNPDLQYRFQLQATTQQGGPG 1002
Score = 149 bits (375), Expect = 3e-35, Method: Composition-based stats.
Identities = 59/324 (18%), Positives = 114/324 (35%), Gaps = 39/324 (12%)
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT------RWKSHLQNY 380
S P ++ H V L W P + N I Y++ L
Sbjct 610 SPGPVPHLELSDRHLLKQSQVHLSWS--PAEDHNSPIEKYDIEFEDKEMAPEKWFSLGKV 667
Query 381 TVNATKLTVNL-TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP--VMDLKAFPKDN 437
N T T+ L Y +T N G + + ++ +A +D++ +
Sbjct 668 PGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSESVVTPEAAPEKNPVDVRGEGNET 727
Query 438 ---------MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
+ W++W P+ +Y ++W + W+++ + + N +
Sbjct 728 NNMVITWKPLRWMDWNAPQ---IQYRVQWRPQGKQET----WRKQTVS-DPFLVVSNTST 779
Query 489 SKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNE-AVLEWDQLPVDV 546
Y I V V G G P+ Y + P P + + + ++ W + +
Sbjct 780 FVPYEIKVQAVNNQGKGPEPQVTIGYSGEDYPQVSPELEDITIFNSSTVLVRWRPVDLAQ 839
Query 547 QNGFIRNYTIFYRTIIG---------NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
G ++ Y + Y +++ + V ++ T LS L + Y V + A+
Sbjct 840 VKGHLKGYNVTYWWKGSQRKHSKRHIHKSHIVVPANTTSAILSGLRPYSSYHVEVQAFNG 899
Query 598 EGGKDGPEFTFTTPKFAQGEIEAI 621
G E+TF+TP+ G EA+
Sbjct 900 RGLGPASEWTFSTPEGVPGHPEAL 923
Score = 144 bits (362), Expect = 1e-33, Method: Composition-based stats.
Identities = 100/603 (17%), Positives = 187/603 (31%), Gaps = 76/603 (13%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P S + + + T C + I W+ + + + +
Sbjct 523 PRSAIEKKGARVTFTCQ-----ASFDPSLQASITWRGDGRDLQERGDSDKYFIEDGKLV- 576
Query 93 DIASLNIQLTCNILTFGQLEQNVYGIT---IISGLPPEKPK-NLSCI-VNEGKKMRCEWD 147
I SL+ N E + ++ G P P LS + + ++ W
Sbjct 577 -IQSLDYSDQGNYSCVASTELDEVESRAQLLVVGSPGPVPHLELSDRHLLKQSQVHLSWS 635
Query 148 GGRETHLET-NFTLKSEW---ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENA 203
+ + + ++ E A K+ TS T+ S +V+ V A N
Sbjct 636 PAEDHNSPIEKYDIEFEDKEMAPEKWFSLGKVPGNQTSTTLKLSP--YVHYTFRVTAINK 693
Query 204 LGKVTSDHINFDPVYKVKPNP-----PHNLSVINSEELSSILKLTWTNPSIK--SVIILK 256
G ++ V P P ++ +E + ++ TW + ++
Sbjct 694 YGPGEPSPVS---ESVVTPEAAPEKNPVDVRGEGNETNNMVI--TWKPLRWMDWNAPQIQ 748
Query 257 YNIQYRTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y +Q+R + TW + D V + F Y +++ + GKG +
Sbjct 749 YRVQWRPQGKQETWRKQTVSDPF-----LVVSNTSTFVPYEIKVQAVNNQGKGPEPQVTI 803
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
SG ED P +P + + TV + W+ + + G + Y VT WK
Sbjct 804 GYSG---EDYPQVSPELEDITIFNSS----TVLVRWRPVDLAQVKGHLKGYNVTYW-WKG 855
Query 376 HLQNY------------TVNATK--LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+ + N T L+ Y + N G A+ T +
Sbjct 856 SQRKHSKRHIHKSHIVVPANTTSAILSGLRPYSSYHVEVQAFNGRGLGPASEWTFSTPEG 915
Query 422 QATHPVMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
HP D L + W P + Y+L + + ++ + D +
Sbjct 916 VPGHPEALHLECQSDTSLLLHWQPPLSHNGVLTGYLLSYHPVEGESKEQLFFNLSDPEL- 974
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE--AV 536
RT+ NL Y + G G E+I P E +V
Sbjct 975 RTHNLTNLNPDLQYRFQLQATTQQG-GPGEAIVREGGTMALFGKPDFGNISATAGENYSV 1033
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN-------VDSSHTEYTLSSLTSDTLYM 589
+ W + I ++ + + + + V + + YT +L DT Y
Sbjct 1034 VSWVPRKGQCN----FRFHILFKALPEGKVSPDHQPQPQYVSYNQSSYTQWNLQPDTKYE 1089
Query 590 VRM 592
+ +
Sbjct 1090 IHL 1092
>sp|Q05695|L1CAM_RAT Neural cell adhesion molecule L1 OS=Rattus
norvegicus OX=10116 GN=L1cam PE=1 SV=3
Length=1259
Score = 212 bits (538), Expect = 3e-55, Method: Composition-based stats.
Identities = 75/408 (18%), Positives = 136/408 (33%), Gaps = 29/408 (7%)
Query 215 DPVYKVKPNPPHNLSVINSEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
+ P P +L + + L S + L+W+ + I KY+I++ K+ +
Sbjct 604 QLLVVGSPGPVPHLELSDRHLLKQSQVHLSWSPAEDHNSPIEKYDIEFEDKEMAPEKWFS 663
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
++S T+ L P+ Y FR+ + + G G S SE + +T E P K P
Sbjct 664 LGKVPGNQTSTTL-KLSPYVHYTFRVTAINKYGPGEPSPVSE--TVVTPEAAPEKNPVDV 720
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW--KSHLQNYTVNATKLTVNL 391
+ + WK L + N + Y V + + TV+ L V+
Sbjct 721 RG----EGNETNNMVITWKPLRWMDWNAPQIQYRVQWRPLGKQETWKEQTVSDPFLVVSN 776
Query 392 TND--RYLATLTVRNLVGKSDAAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTP- 446
T+ Y + N GK +TI D+ P ++ + + V W
Sbjct 777 TSTFVPYEIKVQAVNNQGKGPEPQVTIGYSGEDYPQVSPELEDITIFNSSTVLVRWRPVD 836
Query 447 ----RESVKKY-ILEWCVLSDKAPCITDWQQ---EDGTVHRTYLRGNLAESKCYLITVTP 498
+ ++ Y + W S + + + + L Y + V
Sbjct 837 LAQVKGHLRGYNVTYWWKGSQRKHSKRHVHKSHMVVPANTTSAILSGLRPYSSYHVEVQA 896
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
G G + P + + +L W P NG + Y + Y
Sbjct 897 FNGRGLGPASEWTFSTPEGVPGHPEALHLECQSDTSLLLHWQ--PPLSHNGVLTGYLLSY 954
Query 559 RTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ G D + L++L D Y ++ A T +G +
Sbjct 955 HPLDGESKEQLFFNLSDPELRTHNLTNLNPDLQYRFQLQATTHQGPGE 1002
Score = 150 bits (379), Expect = 9e-36, Method: Composition-based stats.
Identities = 123/718 (17%), Positives = 229/718 (32%), Gaps = 101/718 (14%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTA-SSVTF 91
P S + + + T C + I W+ + + + + +
Sbjct 523 PRSTIEKKGARVTFTCQ-----ASFDPSLQASITWRGDGRDLQERGDSDKYFIEDGQLVI 577
Query 92 TDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPK-NLSCI-VNEGKKMRCEWDGG 149
+ + + + E ++ G P P LS + + ++ W
Sbjct 578 KSLDYSDQGDYSCVASTELDEVESRAQLLVVGSPGPVPHLELSDRHLLKQSQVHLSWSPA 637
Query 150 RETHLET-NFTLKSEW---ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
+ + + ++ E A K+ TS T+ S +V+ V A N G
Sbjct 638 EDHNSPIEKYDIEFEDKEMAPEKWFSLGKVPGNQTSTTLKLSP--YVHYTFRVTAINKYG 695
Query 206 KVTSDHINFDPVYKVKPNP-----PHNLSVINSEELSSILKLTWTNPSIK--SVIILKYN 258
++ V P P ++ +E + ++ TW + ++Y
Sbjct 696 PGEPSPVS---ETVVTPEAAPEKNPVDVRGEGNETNNMVI--TWKPLRWMDWNAPQIQYR 750
Query 259 IQYRTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
+Q+R TW + D V + F Y +++ + GKG +
Sbjct 751 VQWRPLGKQETWKEQTVSDPF-----LVVSNTSTFVPYEIKVQAVNNQGKGPEPQVTIGY 805
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL 377
SG ED P +P + + TV + W+ + + G + Y VT WK
Sbjct 806 SG---EDYPQVSPELEDITIFNSS----TVLVRWRPVDLAQVKGHLRGYNVTYW-WKGSQ 857
Query 378 QNY------------TVNATK--LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA 423
+ + N T L+ Y + N G A+ T +
Sbjct 858 RKHSKRHVHKSHMVVPANTTSAILSGLRPYSSYHVEVQAFNGRGLGPASEWTFSTPEGVP 917
Query 424 THPVMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
HP D L + W P + Y+L + L ++ + D + RT
Sbjct 918 GHPEALHLECQSDTSLLLHWQPPLSHNGVLTGYLLSYHPLDGESKEQLFFNLSDPEL-RT 976
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
+ NL Y + GPG + + G+N +V+ W
Sbjct 977 HNLTNLNPDLQYRFQLQATTHQGPGEAIVREGGTMALFGKPDFGNISVTAGENYSVVSW- 1035
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVN-------VDSSHTEYTLSSLTSDTLYMVRMA 593
+P + Q F + I ++ + + + + V + + YT L DT Y + +
Sbjct 1036 -VPREGQCNF--RFHILFKALPEGKVSPDHQPQPQYVSYNQSSYTQWDLQPDTKYEIHLM 1092
Query 594 ---------AYTDEGGKDGPEFTFTTPKF-AQGEIEAIVVPVCLAFLLTTLLGVLFCFNK 643
A G GP TT F ++G A V A +L L+ ++ CF K
Sbjct 1093 REKVLLHHLAVKTNGT--GPVRVSTTGSFASEGWFIAFVS----AIILLLLILLILCFIK 1146
Query 644 RDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDK 701
R S ++S +S+ + D F + +E + +K
Sbjct 1147 R----------------SKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEK 1188
>sp|G5EF96|UNC40_CAEEL Netrin receptor unc-40 OS=Caenorhabditis
elegans OX=6239 GN=unc-40 PE=1 SV=1
Length=1415
Score = 210 bits (533), Expect = 2e-54, Method: Composition-based stats.
Identities = 100/549 (18%), Positives = 187/549 (34%), Gaps = 53/549 (10%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSE 163
N G+ ++ T P K +L+ + + W + +
Sbjct 514 NEAGMGKFSDSLKVTTNKEQAVPGKVASLTTTATGPETIDIRWSPPSGGQPALRYKIFYS 573
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKP 222
+ + + T T+ + + ++ +EAE + G ++SD +
Sbjct 574 HDPLEKNEKETLITTSTTHYTLHGMDKYTGYQIRIEAEGSNGSGLSSDTVKVRTQSDEPS 633
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIK--SVIILKYNIQYRTKDASTWSQIPPEDTAST 280
PP N+ + S+ ++++W P + + I Y ++Y+TK D T
Sbjct 634 APPVNIQAEA--DSSTSVRVSWDEPEEESVNGEITGYRLKYKTKARGAKGNTLVIDA--T 689
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW-SEEASGITYEDRPSKAPSFWYKIDPS 339
+T+ +L+P T+Y+ R+ + +G G +SDW S + G E+R AP +I P
Sbjct 690 AREYTMGNLEPNTQYLIRMAVVNHNGTGPFSDWVSIDTPGQDKEERTLGAP---REIRPH 746
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL----TNDR 395
G + + W LPP + + Y++ + V A+ + +
Sbjct 747 A--GIDYILVSW--LPPADEQNLVRGYQIGWGLSVPDTETIRVTASTTQYKIARLHSERD 802
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATH-------------------PVMDLKAFPKD 436
Y+ +L N +G T+ + PV
Sbjct 803 YVISLRAFNNLGSGFPIYETVRTLSRETPSHFNEDSDSDDSDVGSSESTPVGVRAEAISA 862
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV 496
+ V WT E+ ++ V A + + T + G L + Y V
Sbjct 863 TSIRVMWTESDETAFN--TQYTVRYSTAVDGNQHRYVNSTETWATVEG-LRPATEYEFAV 919
Query 497 TPVYADGPGSPESI--KAYLKQAPPSKGPT----VRTKKVGKNEAVLEWDQLPVDVQNGF 550
V ++G S S+ + APPS P + + + + L W P NG
Sbjct 920 RAVASNGQLSTWSMATRNRTLAAPPSSAPRDLTVLPAESGDPHSSSLHWQ--PPKYSNGE 977
Query 551 IRNYTIFYRTIIG----NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
I Y +FY + T V + +S+L Y ++ A ++G
Sbjct 978 IEEYLVFYTDRASLADKDWTINYVAGDKLSHQVSNLLPKANYFFKIQARNEKGHGPFSSV 1037
Query 607 TFTTPKFAQ 615
TP
Sbjct 1038 VGYTPSGGA 1046
Score = 165 bits (416), Expect = 3e-40, Method: Composition-based stats.
Identities = 90/437 (21%), Positives = 151/437 (35%), Gaps = 44/437 (10%)
Query 200 AENALGKVT-SDHINFDPVYK----------VKPNPPHNLSVINSEELSSILKLTWTNPS 248
AEN +G S + D + + P L ++ S + + W P
Sbjct 407 AENDVGSEQASAQLLVDAPDSSSVAASSGVPMTSSAPLGLR--STSSGSRFINVEWDPPV 464
Query 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
++ I++Y+I Y+ I T++T +S +P T Y+ R+ E G G
Sbjct 465 QRNGNIMRYHIFYKDNLIDRERMINSSSTSATLTSL-----QPSTMYLIRVTAENEAGMG 519
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
+SD S + + + P K S + G T+ + W + L Y++
Sbjct 520 KFSD-SLKVTTNKEQAVPGKVASL-----TTTATGPETIDIRWSPPSGGQPA---LRYKI 570
Query 369 TLT----RWKSHLQNYTVNATKLTVNL--TNDRYLATLTVR--NLVGKSDAAVLTIPACD 420
+ T + T T++ Y + N G S V D
Sbjct 571 FYSHDPLEKNEKETLITTSTTHYTLHGMDKYTGYQIRIEAEGSNGSGLSSDTVKVRTQSD 630
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRE-SVKKYILEWCVLSD-KAPCITDWQQEDGTVH 478
+ PV + V W P E SV I + + KA
Sbjct 631 EPSAPPVNIQAEADSSTSVRVSWDEPEEESVNGEITGYRLKYKTKARGAKGNTLVIDATA 690
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIK-----AYLKQAPPSKGPTVRTKKVGKN 533
R Y GNL + YLI + V +G G K+ P G +
Sbjct 691 REYTMGNLEPNTQYLIRMAVVNHNGTGPFSDWVSIDTPGQDKEERTLGAPREIRPHAGID 750
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
++ W P D QN +R Y I + + + + V +S T+Y ++ L S+ Y++ +
Sbjct 751 YILVSWLP-PADEQN-LVRGYQIGWGLSVPDTETIRVTASTTQYKIARLHSERDYVISLR 808
Query 594 AYTDEGGKDGPEFTFTT 610
A+ + G T T
Sbjct 809 AFNNLGSGFPIYETVRT 825
>sp|P70232|NCHL1_MOUSE Neural cell adhesion molecule L1-like protein
OS=Mus musculus OX=10090 GN=Chl1 PE=1 SV=2
Length=1209
Score = 208 bits (530), Expect = 3e-54, Method: Composition-based stats.
Identities = 113/616 (18%), Positives = 203/616 (33%), Gaps = 69/616 (11%)
Query 38 VQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASL 97
+ + C +YF +VW+ T P E ++
Sbjct 435 TVVGYSAFLHC-------EYFASPKATVVWEVADETHPLEGDRYHTHENGTLEIYRTTEE 487
Query 98 NIQLTCNILTFGQLEQNVYGITIISG--------LPPEKPKNLSCIVNEGKKMRCEWDGG 149
+ + + IT + P+ P+ V E + CE
Sbjct 488 DA---GSYSCWVDNAMGKAVITANLDIRNATKLRVSPKNPRIPKSHVLE---LYCE--SQ 539
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG---K 206
++HL+ + L F + +D + + NI + +
Sbjct 540 CDSHLKHSLKLSWSKDGEAFEMNGTEDG---RIVIDGAYLTISNITAEDQGVYSCSAQTS 596
Query 207 VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA 266
+ S P+PP NL + SE + ++L+W + I +Y +++
Sbjct 597 LDSTSEKTQVTVLGVPDPPGNLHL--SERQNRSVRLSWEAGDDHNSKISEYIVEFEGNRE 654
Query 267 ST--WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
W ++ T V L P+ Y FR+ + E G+ + S S+ T
Sbjct 655 EPGKWEELTRVQGEETD---VVLSLAPYVRYQFRVTAVNEVGRSHASLPSD--HHETPPA 709
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR--WKSHLQNYTV 382
P K P + + + W+ L E NG L+Y+V+ + V
Sbjct 710 APDKNPQNIRV----QASQPKEMIIKWEPLKSMEQNGPGLEYKVSWKPQGAPEEWEEEIV 765
Query 383 NATKLTVNLT--NDRYLATLTVRNLVGKS--DAAVLTIPACDFQATHPVMDLKAFPKDNM 438
L V Y + N +G S V D+ +T PV+ +
Sbjct 766 TNHTLRVMTPTVYAPYDVKVQAINQLGSSPDPQPVTLYSGEDYPSTAPVIQRVDVMNSTL 825
Query 439 LWVEWTTPRESV-----KKYILEWC-----VLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
+ V W++ + + Y + W + P + + G + + L
Sbjct 826 VKVTWSSIPKETVHGLLRGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPS-LDP 884
Query 489 SKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
+ +TV + G G E + P + ++ KV K+ A L W
Sbjct 885 FSEFHLTVLAYNSKGAGPESEPYIFQTPEGVPEQPSFLKVIKVDKDTATLSWGLPK--KL 942
Query 548 NGFIRNYTIFYRTI-----IGNETAVNVDS-SHTEYTLSSLTSDTLYMVRMAAYTDEG-G 600
NG + Y + Y+ I +G +NV + S + + LS+L S T Y + A T G G
Sbjct 943 NGNLTGYLLQYQIINDTYELGELNEINVTTPSKSSWHLSNLNSTTKYKFYLRACTSRGCG 1002
Query 601 KDGPEFTFTTPKFAQG 616
K E T + ++G
Sbjct 1003 KPISEEGATLGEGSKG 1018
Score = 133 bits (335), Expect = 2e-30, Method: Composition-based stats.
Identities = 111/642 (17%), Positives = 196/642 (31%), Gaps = 109/642 (17%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P+S V S+ +C + + I W+ N I K + ++FT
Sbjct 337 PQSAVYSTGSSGILLCEAEGE-------PQPTIKWRLNGLPIEKHPFPGDFMFPREISFT 389
Query 93 DIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPEKPKN-------------LSCIVNE 138
++ + C I +I +P K KN L C
Sbjct 390 NLLPNHTGVYQCEASNIHGTILANANIDVIDVIPLIKTKNEENYATVVGYSAFLHCEYFA 449
Query 139 GKKMRCEWDGGRETHLET--NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV 196
K W+ ETH + E T + + SC
Sbjct 450 SPKATVVWEVADETHPLEGDRYHTH-ENGTLEIYRTTEEDAGSYSC-------------- 494
Query 197 WVEAENALGKVTSDH---INFDPVYKVKPNPPHNLSVINSE---------ELSSILKLTW 244
WV +NA+GK I +V P P E L LKL+W
Sbjct 495 WV--DNAMGKAVITANLDIRNATKLRVSPKNPRIPKSHVLELYCESQCDSHLKHSLKLSW 552
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPED--TASTRSSFTVQDLKPFTEYVFRIRCM 302
+ KD + ED + T+ ++ + V+
Sbjct 553 S------------------KDGEAFEMNGTEDGRIVIDGAYLTISNITAEDQGVYSCSAQ 594
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
D + E + +T P + + R+V+L W+ + N K
Sbjct 595 TSL------DSTSEKTQVTVLGVPDPPGNLHL-----SERQNRSVRLSWEA--GDDHNSK 641
Query 363 ILDYEVTLT-------RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT 415
I +Y V +W+ + + RY +T N VG+S A++ +
Sbjct 642 ISEYIVEFEGNREEPGKWEELTRVQGEETDVVLSLAPYVRYQFRVTAVNEVGRSHASLPS 701
Query 416 IPACDFQATH---PVMDLKAFPKDNMLWVEWTTPRESVKKYI-LEWCVLSDKAPCITDWQ 471
A P + + ++W + + LE+ V +W+
Sbjct 702 DHHETPPAAPDKNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYKVSWKPQGAPEEWE 761
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKV 530
+E T H + Y + V + G P+ + Y + PS P ++ V
Sbjct 762 EEIVTNHTLRVMTP-TVYAPYDVKVQAINQLGSSPDPQPVTLYSGEDYPSTAPVIQRVDV 820
Query 531 GKNEAV-LEWDQLPVDVQNGFIRNYTIFY---------RTIIGNETAVNVDSSHTEYTLS 580
+ V + W +P + +G +R Y I + RT + +
Sbjct 821 MNSTLVKVTWSSIPKETVHGLLRGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVP 880
Query 581 SLTSDTLYMVRMAAYTDEGGKDGPE-FTFTTPKFAQGEIEAI 621
SL + + + + AY +G E + F TP+ + +
Sbjct 881 SLDPFSEFHLTVLAYNSKGAGPESEPYIFQTPEGVPEQPSFL 922
Score = 132 bits (331), Expect = 6e-30, Method: Composition-based stats.
Identities = 78/511 (15%), Positives = 176/511 (34%), Gaps = 45/511 (9%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIP----KEQYTIINRTA 86
+SP++P + C + H + + W + ++ +I+
Sbjct 519 VSPKNPRIPKSHVLELYC-ESQCDSHLKH--SLKLSWSKDGEAFEMNGTEDGRIVID--G 573
Query 87 SSVTFTDIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCE 145
+ +T ++I + + +C+ T +T++ P+ P NL + + +R
Sbjct 574 AYLTISNITAEDQGVYSCSAQTSLDSTSEKTQVTVLG--VPDPPGNLHLSERQNRSVRLS 631
Query 146 WDGGRETHLE-TNFTLKSEWATHKF-ADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENA 203
W+ G + + + + + ++ E + + R V S +V + V A N
Sbjct 632 WEAGDDHNSKISEYIVEFEGNREEPGKWEELTRVQGEETDVVLSLAPYVRYQFRVTAVNE 691
Query 204 LGKV-TSDHINFDPVYKVKPNP-PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
+G+ S + P+ P N+ V S+ I+K ++ L+Y + +
Sbjct 692 VGRSHASLPSDHHETPPAAPDKNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYKVSW 751
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+ + A + E + + + Y +++ + + G S + + +
Sbjct 752 KPQGAP--EEWEEEIVTNHTLRVMTPTV--YAPYDVKVQAINQLGS---SPDPQPVTLYS 804
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
ED PS AP V++ W ++P +G + Y++ + KS L T
Sbjct 805 GEDYPSTAPVIQRV----DVMNSTLVKVTWSSIPKETVHGLLRGYQINWWKTKSLLDGRT 860
Query 382 VNATKLTVNLTNDR-------------YLATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+ + R + T+ N G + I
Sbjct 861 HPKEVNILRFSGQRNSGMVPSLDPFSEFHLTVLAYNSKGAGPESEPYIFQTPEGVPEQPS 920
Query 429 DLKAFPKD-NMLWVEWTTPRE---SVKKYILEWCVLSDK-APCITDWQQEDGTVHRTYLR 483
LK D + + W P++ ++ Y+L++ +++D + ++
Sbjct 921 FLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYELGELNEINVTTPSKSSWHL 980
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYL 514
NL + Y + + G G P S +
Sbjct 981 SNLNSTTKYKFYLRACTSRGCGKPISEEGAT 1011
>sp|Q2QI47|USH2A_MOUSE Usherin OS=Mus musculus OX=10090 GN=Ush2A
PE=1 SV=2
Length=5193
Score = 209 bits (531), Expect = 6e-54, Method: Composition-based stats.
Identities = 98/443 (22%), Positives = 156/443 (35%), Gaps = 43/443 (10%)
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPN--PPHNLSVINSEELSSILKLTWTNPS 248
++A A G S + + P PP N++ +SE L L+W+ P
Sbjct 3552 LQEYSYQLKACTAAGCAVSCKVVAATTQR-SPENVPPPNITAQSSE----TLHLSWSVPE 3606
Query 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
I Y + K + DT+ R TV L+P+T Y F + G
Sbjct 3607 KMKDAIKAYQLWLDGKG------LIYTDTSD-RRQHTVTGLQPYTNYSFTLAVCTSVG-- 3657
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ-GYRTVQLVWKTLPPFEANGKILDYE 367
SE G T + P W + P H TV+L W PP NG I Y+
Sbjct 3658 --CTSSEPCVGQTLQAAPQG---VW--VTPRHIIINSTTVELYWN--PPERPNGLISQYQ 3708
Query 368 VTLTR---WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS--DAAVLTIPACDFQ 422
+ N + + L RY+ L R G S + ++ +P +
Sbjct 3709 LRRNGSLLLVGGRDNQSFTDSNLE---PGSRYIYKLEARTGGGSSWSEDYLVQMPLWTPE 3765
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
HP ++ D+ ++V W TP + K +E+ +L +T +L
Sbjct 3766 DIHPPCNVTVLGSDS-IFVAWPTPGNLLPKIPVEYSILLSGG-SVTLLVFSVRHRQSAHL 3823
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
+ NL+ Y I + G G +A P K +G + ++W +
Sbjct 3824 K-NLSPFTQYEIRIQACQNGGCGVSPGTYVRTLEAAPVGLMPPLLKALGSSCIEVKW--M 3880
Query 543 PVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS----LTSDTLYMVRMAAYTDE 598
P NG I +Y + R E ++ S + L TLY R+ A+ +
Sbjct 3881 PPTRPNGIITSYVVHRRPADTEEESLLFVWSEGALEFTDDTGTLRPFTLYEYRVRAWNSQ 3940
Query 599 GGKDGPEFTFTTPKFAQGEIEAI 621
G D P T T + + A
Sbjct 3941 GAVDSPWSTIQTLEAPPRGLPAP 3963
Score = 199 bits (505), Expect = 9e-51, Method: Composition-based stats.
Identities = 107/605 (18%), Positives = 180/605 (30%), Gaps = 96/605 (16%)
Query 68 KTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGIT-IISGLPP 126
+N + Y + RT ++++ + + L V G I P
Sbjct 3728 DSNLEPGSRYIYKLEARTGGGSSWSEDYLVQMPLWTPEDIHPPCNVTVLGSDSIFVAWP- 3786
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
P NL + +++ + +
Sbjct 3787 -TPGNL------------------LPKIPVEYSILLSGGSVTLLVFSVR---HRQSAHLK 3824
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVY--KVKPNPPHNLSVINSEELSSILKLTW 244
+ F E+ ++A G S + V PP + SS +++ W
Sbjct 3825 NLSPFTQYEIRIQACQNGGCGVSPGTYVRTLEAAPVGLMPP-----LLKALGSSCIEVKW 3879
Query 245 TNPSIKSVIILKYNIQYRTKDAST------WSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
P+ + II Y + R D WS+ E T T + L+PFT Y +R
Sbjct 3880 MPPTRPNGIITSYVVHRRPADTEEESLLFVWSEGALEFTDDTGT------LRPFTLYEYR 3933
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+R G S WS + T E P P+ + +H + L W P
Sbjct 3934 VRAWNSQGA-VDSPWS---TIQTLEAPPRGLPAPRVQATSAH-----SAMLNWTE--PEA 3982
Query 359 ANGKILDYEVTLTR-------WKSHLQNYTVNATKLTVNLTN----DRYLATLTVRNLVG 407
NG I Y V S + +TV T +L Y + N G
Sbjct 3983 PNGLISQYHVIYQERPDAAAPGSSTVHAFTVTGTSRQAHLFGLEPFTTYHIGVVAVNSAG 4042
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNM--LWVEWTTPRESVKKYILEWCVLSDKAP 465
K + I + A +M+ ++ L ++W+ P + I + + +D
Sbjct 4043 KVSSPWTLIKTLE-SAPSGLMNFTVEQREKGRALLLQWSEPVK-TNGVIKAYNIFNDG-- 4098
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
E + R +L LA Y + + G + ++APP
Sbjct 4099 -----VLEYSGLGRQFLFRRLAPFTLYTLILEACTTAGCAHSVPQPLWTEEAPPDTQMAP 4153
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR------------TIIGNETAVNVDSS 573
+ VG L W Q NG I +Y + R GN ++
Sbjct 4154 TIQSVGPTNVRLHWSQ--PASPNGKIIHYEVIRRRSEEEDWGNTTWQADGNTVFTEYNTQ 4211
Query 574 HTEYTLS--SLTSDTLYMVRMAAYTDEGGKDGPEFTFTT----PKFAQGEIEAIVVPVCL 627
+ + L Y R+ A+ G T P + V L
Sbjct 4212 GNAWVYNDTGLQPWRQYAYRICAWNSAGHTCSSWNVVRTLQAPPDGLSPPEISYVSMSPL 4271
Query 628 AFLLT 632
L++
Sbjct 4272 QLLIS 4276
Score = 169 bits (427), Expect = 3e-41, Method: Composition-based stats.
Identities = 99/523 (19%), Positives = 169/523 (32%), Gaps = 50/523 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH-LETNFTLKSEWATHKFADCKAKRDTPTSCT 183
PPE + + + + W R H L ++ L+ + A
Sbjct 4435 PPENMDPPTLHITGPESIEITWTPPRNPHGLIRSYELRRDGAIVYVGLETR--------Y 4486
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI-LKL 242
D++ V V A N+ G V S + + P+ P L ++ L
Sbjct 4487 HDFTLAPGVEYSYSVTATNSRGSVLSPLVK----GQTSPSAPSGLQPPKLHSGDALELLA 4542
Query 243 TWTNPSIKSVIILKYNIQYRT--KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
W P + I+ Y + R + + I ++ S TV+ LKPF Y R++
Sbjct 4543 DWDPPVRTNGKIINYTLFVREMFEGKTRAMSINTTHSSFGTRSLTVKHLKPFHRYEVRVQ 4602
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
G SE S T E P + P+ ++ + V + W P + N
Sbjct 4603 ACTALG----CTSSEWTSTQTSEVPPLRQPAPHLEVQTATGGFQPIVAVWWAG--PLQPN 4656
Query 361 GKILDYEVTLTR---WKSHLQNYTVNATKL-----TVNLTNDRYLATLTVRNLVGKSDAA 412
GKI+ +E+ + W + + + L Y + N GK+ +
Sbjct 4657 GKIICFELYRRQVAAWPGTSSSLLIYNGSFRSFMDSELLPFTEYEYQVWAVNSAGKAASN 4716
Query 413 VLTIPACDFQAT--HPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW 470
++ + I + V S+ T
Sbjct 4717 WTRCRTGPAPPEGLQAPTFHTVSSTRAVVNIS---VPSRPNGNISLFRVFSNS--SGTHV 4771
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-ESIKAYLKQAPPSKGPTVRTKK 529
+GT + L L+ Y I V S + + APPS + +
Sbjct 4772 TLSEGTATQQTLHD-LSPFTTYTIGVEACTCFNCCSRGPTAELRTHPAPPSGLSPPQVQT 4830
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE---------YTLS 580
+G A + W P + NG I +Y + + ++A SHTE +L+
Sbjct 4831 LGSRMASVHW--TPPLLPNGVIHSYELQLQRACPPDSAPRCPPSHTERKYWGPGHRASLA 4888
Query 581 SLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
L +T Y V++ AY + G F+T K V
Sbjct 4889 GLQPNTAYGVQVVAYNEAGSTASGWTNFSTKKEMPQYQALFSV 4931
Score = 166 bits (419), Expect = 3e-40, Method: Composition-based stats.
Identities = 82/458 (18%), Positives = 136/458 (30%), Gaps = 56/458 (12%)
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
F + V A N+ GKV+S + N +V E L L W+ P
Sbjct 4028 FTTYHIGVVAVNSAGKVSSPWTLIKTLESAPSGL-MNFTVEQRE-KGRALLLQWSEPVKT 4085
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
+ +I YNI + + F + L PFT Y + G +
Sbjct 4086 NGVIKAYNI----------FNDGVLEYSGLGRQFLFRRLAPFTLYTLILEACTTAGCAH- 4134
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S T E P + + + G V+L W P NGKI+ YEV
Sbjct 4135 ---SVPQPLWTEEAPPDTQMAPTIQ-----SVGPTNVRLHWSQ--PASPNGKIIHYEVIR 4184
Query 371 TR-----WKSHLQNYTVNATKLTVNLTNDR-------------YLATLTVRNLVGKSDAA 412
R W + N N + Y + N G + ++
Sbjct 4185 RRSEEEDWGNTTWQADGNTVFTEYNTQGNAWVYNDTGLQPWRQYAYRICAWNSAGHTCSS 4244
Query 413 VLTIPACDFQAT--HPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW 470
+ P L + W PR S I + + D ++
Sbjct 4245 WNVVRTLQAPPDGLSPPEISYVSMSPLQLLISWLPPRHS-NGVIQGYRLQRDGVLPALNF 4303
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKV 530
+Y+ L Y + G + E + PPS+ +
Sbjct 4304 NAS----TFSYMDSQLLPFSTYSYAILACTGGGCCTSEPTNITTPEVPPSEVSPPVLWDI 4359
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMV 590
++ + W P + NG I Y + G E ++ + LS+L T Y +
Sbjct 4360 SAHQMNVSWS--PPSIPNGKIVKYLL---QCDGEE---HLAGQGLSFLLSNLQPSTQYNI 4411
Query 591 RMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLA 628
+ A T G + T + ++ + +
Sbjct 4412 SLVACTSGGCTASRTTSAWTKEAPPENMDPPTLHITGP 4449
Score = 163 bits (411), Expect = 2e-39, Method: Composition-based stats.
Identities = 85/498 (17%), Positives = 151/498 (30%), Gaps = 61/498 (12%)
Query 126 PEKPKNLSCIVNEGK-KMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P N + E + +W +TN +K+ F D + +
Sbjct 4058 PSGLMNFTVEQREKGRALLLQWSEPV----KTNGVIKAYNI---FNDGVLEYSGLGRQFL 4110
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
F + +EA G S + P+ ++ + + ++L W
Sbjct 4111 FRRLAPFTLYTLILEACTTAGCAHSVPQPL-WTEEAPPDTQMAPTIQSVG--PTNVRLHW 4167
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQ----------IPPEDTASTRSSFTVQDLKPFTE 294
+ P+ + I+ Y + R + W +T + L+P+ +
Sbjct 4168 SQPASPNGKIIHYEVIRRRSEEEDWGNTTWQADGNTVFTEYNTQGNAWVYNDTGLQPWRQ 4227
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK--APSFWYKIDPSHTQGYRTVQLVWK 352
Y +RI G S W T + P P Y + + + W
Sbjct 4228 YAYRICAWNSAGH-TCSSW---NVVRTLQAPPDGLSPPEISYV-----SMSPLQLLISW- 4277
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV----NLTNDRYLATLTVRNLVG- 407
LPP +NG I Y + L NA+ + L Y + G
Sbjct 4278 -LPPRHSNGVIQGYRLQR---DGVLPALNFNASTFSYMDSQLLPFSTYSYAILACTGGGC 4333
Query 408 -KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
S+ +T P P + + V W+ P I+++ + D
Sbjct 4334 CTSEPTNITTPEVPPSEVSPPVLWDISAH--QMNVSWSPPS-IPNGKIVKYLLQCDGEEH 4390
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVR 526
+ ++L NL S Y I++ + G + + A+ K+APP
Sbjct 4391 L-------AGQGLSFLLSNLQPSTQYNISLVACTSGGCTASRTTSAWTKEAPPENMDPPT 4443
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDT 586
G + W P +G IR+Y + + A+ T Y +L
Sbjct 4444 LHITGPESIEITW--TPPRNPHGLIRSYEL------RRDGAIVYVGLETRYHDFTLAPGV 4495
Query 587 LYMVRMAAYTDEGGKDGP 604
Y + A G P
Sbjct 4496 EYSYSVTATNSRGSVLSP 4513
Score = 161 bits (407), Expect = 8e-39, Method: Composition-based stats.
Identities = 85/509 (17%), Positives = 158/509 (31%), Gaps = 63/509 (12%)
Query 125 PPE--KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSC 182
PP+ P +S + ++ W R +N ++ + T
Sbjct 4254 PPDGLSPPEISYVSMSPLQLLISWLPPR----HSNGVIQGYRLQRDGVLPALNFNASTFS 4309
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN---PP--HNLSVINSEELS 237
+D + F + A G TS+ N +V P+ PP ++S
Sbjct 4310 YMDSQLLPFSTYSYAILACTGGGCCTSEPTNI-TTPEVPPSEVSPPVLWDISAHQMN--- 4365
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
++W+ PSI + I+KY +Q + E A SF + +L+P T+Y
Sbjct 4366 ----VSWSPPSIPNGKIVKYLLQCDGE----------EHLAGQGLSFLLSNLQPSTQYNI 4411
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRP--SKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
+ G S S T E P P+ H G ++++ W P
Sbjct 4412 SLVACTSGG----CTASRTTSAWTKEAPPENMDPPTL-------HITGPESIEITW--TP 4458
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT 415
P +G I YE+ ++ T Y ++T N G + +
Sbjct 4459 PRNPHGLIRSYELRRDGAIVYVGLETRYHD--FTLAPGVEYSYSVTATNSRGSVLSPL-- 4514
Query 416 IPACDFQATHPVMDLKAFPKDNMLWV--EWTTPRESVKKYILEWCVLSD-----KAPCIT 468
+ + + + L + +W P I+ + + K ++
Sbjct 4515 VKGQTSPSAPSGLQPPKLHSGDALELLADWDPPV-RTNGKIINYTLFVREMFEGKTRAMS 4573
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTK 528
R+ +L Y + V A G S E + PP + P +
Sbjct 4574 INTTHSSFGTRSLTVKHLKPFHRYEVRVQACTALGCTSSEWTSTQTSEVPPLRQPAPHLE 4633
Query 529 KVGKN---EAVLEWDQLPVDVQNGFIRNYTIFYRTI----IGNETAVNVDSSHTEYTLSS 581
+ ++ NG I + ++ R + + + + + S + S
Sbjct 4634 VQTATGGFQPIVAVWWAGPLQPNGKIICFELYRRQVAAWPGTSSSLLIYNGSFRSFMDSE 4693
Query 582 LTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
L T Y ++ A G T
Sbjct 4694 LLPFTEYEYQVWAVNSAGKAASNWTRCRT 4722
Score = 146 bits (367), Expect = 5e-34, Method: Composition-based stats.
Identities = 83/560 (15%), Positives = 148/560 (26%), Gaps = 62/560 (11%)
Query 103 CNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKS 162
C Q + + LPPE+ V + + + W R L
Sbjct 2114 CTQAGCTNSSQVILHT---AQLPPEQVDPPGLTVLDSRTIHVRWKQPR--QLNGILERYI 2168
Query 163 EWATHKFADCKAKRDTPTSCTVDYSTVYFVN-----IEVWVEAENALGKVTSDHINFDPV 217
+ + + S + V + + G TS+
Sbjct 2169 LYILNPIHNSTMWSVVYNSTEKLQAHVLHHLSPGGLYLIRLRVCTGGGCTTSEPSQALME 2228
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
+ P + S + ++WT P + +I Y +
Sbjct 2229 ETIPEGVPAPRAHSYSPD---SFNISWTEPEYPNGVITTYEL----------YLDDTLIH 2275
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
S+ S P + + F+++ G T E P + K +
Sbjct 2276 NSSGLSCHAYGFDPGSLHTFQVQACTAKGCAL----GPLVGNRTLEAPPEGVVNVLVKPE 2331
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW----KSHLQNYTVNATKLTVNLTN 393
G R + W P NG+ L Y V T ++ ++ TK +
Sbjct 2332 -----GSREAHVRWDA--PAHPNGR-LTYSVHFTGSFYADQAGDNYTLLSGTKTIRGIEG 2383
Query 394 DR-------------YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW 440
R Y+ + N G + +++ + A L
Sbjct 2384 SRLWVLVDGLVPCSHYMVQVNASNSRGSVLSDPVSVEMPPGAPDGLLSPRLAAAAPTSLQ 2443
Query 441 VEWTTPRESVKKYILEWCVLSDKAPCITDWQQE--DGTVHRTYLRGNLAESKCYLITVTP 498
V W+TP + + + P + + +Y L Y +
Sbjct 2444 VVWSTPARNNAPGSPRYQLQMRPGPSTHGRLELFPIPSASLSYEVTGLQPFTVYEFRLVA 2503
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
G + P V + W Q NG I +Y I+
Sbjct 2504 TNGFGTAYSAWTPLMTTEDKPGPIDAPILINVKARMLSVIWRQ--PAKCNGAITHYNIY- 2560
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEI 618
+ + V T YT+ L Y ++ A T +G P T G
Sbjct 2561 ---LHGRLYLTVSGRVTNYTVVPLHPYKAYHFQVEACTSQGCSKSPSSE--TVWTLPGNP 2615
Query 619 EAIVVPVCLAFLLTTLLGVL 638
E I P + T+++
Sbjct 2616 EGIPSPQLFPYTPTSIIVTW 2635
Score = 145 bits (365), Expect = 8e-34, Method: Composition-based stats.
Identities = 93/583 (16%), Positives = 177/583 (30%), Gaps = 63/583 (11%)
Query 77 EQYTIINRTASSVTFTDIASLNIQLT-CNILTFGQLEQNVYGITIISGLPPEKPKNLSC- 134
E + + + S + LT C+ + Q + P E P+ +
Sbjct 1999 ELHDTSTHSGVLIGLHPFHSYTVTLTACSRAGCTESSQA-----LSISTPQEAPQEVQAP 2053
Query 135 -IVNEGKKMRCEWDGGRE-THLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV 192
V + W R+ + T ++L + K + T T F
Sbjct 2054 VAVALPNSLSFFWSLPRQANGIITQYSLYVD--GRLVYTGKGQNYTVT------DLRVFA 2105
Query 193 NIEVWVEAENALGKVTSDHINFDPVYKVKPNP--PHNLSVINSEELSSILKLTWTNPSIK 250
E+ V A G S + ++ P P L+V++ S + + W P
Sbjct 2106 AYEIIVGACTQAGCTNSSQVILH-TAQLPPEQVDPPGLTVLD----SRTIHVRWKQPRQL 2160
Query 251 SVIILKYNIQYRTK--DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
+ I+ +Y + +++ WS + ++ + + L P Y+ R+R G
Sbjct 2161 NGILERYILYILNPIHNSTMWSVV--YNSTEKLQAHVLHHLSPGGLYLIRLRVCTGGGCT 2218
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
SE + + E P P+ +H+ + + W P NG I YE+
Sbjct 2219 T----SEPSQALMEETIPEGVPAPR-----AHSYSPDSFNISWTE--PEYPNGVITTYEL 2267
Query 369 TLTRWKSHLQNYTVNATKLTVNL----TNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
L H N++ L+ + + + G + ++ +
Sbjct 2268 YLDDTLIH------NSSGLSCHAYGFDPGSLHTFQVQACTAKGCALGPLVGNRTLEAPPE 2321
Query 425 HPVMDLKAFPKDNMLWVEWTTP--RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT-- 480
V L V W P Y + + ++ GT
Sbjct 2322 GVVNVLVKPEGSREAHVRWDAPAHPNGRLTYSVHFTGSFYADQAGDNYTLLSGTKTIRGI 2381
Query 481 ------YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE 534
L L Y++ V + G + + + P + R
Sbjct 2382 EGSRLWVLVDGLVPCSHYMVQVNASNSRGSVLSDPVSVEMPPGAPDGLLSPRLAAAAPTS 2441
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTII---GNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
+ W + G R Y + R G + S+ Y ++ L T+Y R
Sbjct 2442 LQVVWSTPARNNAPGSPR-YQLQMRPGPSTHGRLELFPIPSASLSYEVTGLQPFTVYEFR 2500
Query 592 MAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTL 634
+ A G T + G I+A ++ A +L+ +
Sbjct 2501 LVATNGFGTAYSAWTPLMTTEDKPGPIDAPILINVKARMLSVI 2543
Score = 142 bits (358), Expect = 5e-33, Method: Composition-based stats.
Identities = 77/444 (17%), Positives = 151/444 (34%), Gaps = 39/444 (9%)
Query 171 DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
D + F V A + G V+SD + + P
Sbjct 1895 DSILVYRGSQQSVYESGLQPFTEYLYRVTASHEGGAVSSDWSRGRTLGTAPQSVPTPSRA 1954
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA---STRSSFTVQ 287
+ S +++ W P++ ++ KY ++ ++D+S ++P T ++ S +
Sbjct 1955 QSING--SSVEVAWNEPAVVKGVLEKYVLKAYSEDSS-QPRVPSASTELHDTSTHSGVLI 2011
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV 347
L PF Y + G ++ S+ S T ++ P + P ++
Sbjct 2012 GLHPFHSYTVTLTACSRAGC---TESSQALSISTPQEAPQE------VQAPVAVALPNSL 2062
Query 348 QLVWKTLPPFEANGKILDYEVTLTR---WKSHLQNYTVNATKLTVNLTNDRYLATLTVRN 404
W P +ANG I Y + + + QNYTV ++ Y +
Sbjct 2063 SFFWS--LPRQANGIITQYSLYVDGRLVYTGKGQNYTVTDLRVFA-----AYEIIVGACT 2115
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
G ++++ + + + V W PR+ ILE +L
Sbjct 2116 QAGCTNSSQVILHTAQLPPEQVDPPGLTVLDSRTIHVRWKQPRQ--LNGILERYILYILN 2173
Query 465 P--CITDWQQEDGTVHR--TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS 520
P T W + + ++ +L+ YLI + G + E +A +++ P
Sbjct 2174 PIHNSTMWSVVYNSTEKLQAHVLHHLSPGGLYLIRLRVCTGGGCTTSEPSQALMEETIPE 2233
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLS 580
P R + + W + + NG I Y ++ + + +SS
Sbjct 2234 GVPAPRAHSYSPDSFNISWTE--PEYPNGVITTYELYL------DDTLIHNSSGLSCHAY 2285
Query 581 SLTSDTLYMVRMAAYTDEGGKDGP 604
+L+ ++ A T +G GP
Sbjct 2286 GFDPGSLHTFQVQACTAKGCALGP 2309
Score = 138 bits (348), Expect = 1e-31, Method: Composition-based stats.
Identities = 77/572 (13%), Positives = 165/572 (29%), Gaps = 51/572 (9%)
Query 77 EQYTIINRTASSVTFTDIASLNIQLT----CNILTFGQLEQNVYGITIISGLPPEKPKNL 132
Y ++ ++ T + C + + T+ G P P
Sbjct 2564 RLYLTVSGRVTNYTVVPLHPYKAYHFQVEACTSQGCSKSPSSETVWTLP-GNPEGIPS-P 2621
Query 133 SCIVNEGKKMRCEWDGGR--ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY 190
+ W + +E + + + + +D
Sbjct 2622 QLFPYTPTSIIVTWQPSAHLDLLVENVTIERRVKGKKEVRNLVTLARSQAMKFIDNDPAL 2681
Query 191 --FVNIEVWVEAENALGKVTSDHINFDPVYKVKPN--PPHNLSVINSEELSSILKLTWTN 246
+ E V G S +P+ P + V+ ++++W
Sbjct 2682 RPWTRYEYRVLGSTLDGGTNSSAWVEVTTRPCRPSGVQPPTVRVL----APDTVEVSWKA 2737
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR-IRCMKED 305
P +++ IL Y I+ I + +S S V+ L PFT Y + C +
Sbjct 2738 PLMQNGDILSYEIRMPEP------LIKMTNMSSIMLSHLVKHLIPFTNYSVTIVACSGGN 2791
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G S T+ P + + V + W+ PP + NG L
Sbjct 2792 GYLAGCTESPPTLATTHPAPPQELAPLSVIL-----LSESDVGISWQ--PPSKPNGPNLR 2844
Query 366 YEVTLTRWKSHLQNYTVNATKLTVNLTN--------------DRYLATLTVRNLVGKSDA 411
YE+ + + L + L N+ + Y L V N VG + +
Sbjct 2845 YELLRCKIQQPLASNPPEDLNLWHNIYSGTRWFYKDKGLSRFTTYEYKLFVHNSVGFTPS 2904
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
+T+ + + V W P + +E+ L + +
Sbjct 2905 REVTVTTLAGSPERGATVTASILNHTAIDVRWKKPTFQDLQGDVEYYTLFWSSGTSEESL 2964
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
+ V ++ G L+ + Y + + + + + + P +
Sbjct 2965 KIFPDV-DFHVIGQLSPNVEYQVFLLVFNGVHAINSTVVHVTMWEEEPQGMLPPEVVIIN 3023
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
+ W N + +++ + N+ + + L L+ T+Y ++
Sbjct 3024 STAVRVIW--TSPSNPNAVVTESSVY----VNNKLYKTGTDAPGSFVLEDLSPFTIYDIQ 3077
Query 592 MAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
+ T + +T + +I V+
Sbjct 3078 VEVCTKDACVKSNGTQVSTAEDTPSDISIPVI 3109
Score = 138 bits (347), Expect = 1e-31, Method: Composition-based stats.
Identities = 92/582 (16%), Positives = 174/582 (30%), Gaps = 83/582 (14%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSC 182
+PP + +M W + + + L+ D +
Sbjct 4346 VPPSEVSPPVLWDISAHQMNVSWSPPSIPNGKIVKYLLQC--------DGEEHLAGQGLS 4397
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP---NPPHNLSVINSEELSSI 239
+ + + + A + G T+ + P +PP L + E
Sbjct 4398 FLLSNLQPSTQYNISLVACTS-GGCTASRTTSAWTKEAPPENMDPPT-LHITGPE----S 4451
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+++TWT P +I Y ++ + + L P EY + +
Sbjct 4452 IEITWTPPRNPHGLIRSYELRRDGA----------IVYVGLETRYHDFTLAPGVEYSYSV 4501
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSK--APSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
G S S G T PS P H+ + W PP
Sbjct 4502 TATNSRG----SVLSPLVKGQTSPSAPSGLQPPKL-------HSGDALELLADWD--PPV 4548
Query 358 EANGKILDYEVTLTR-WKSHLQNYTVNATKLTVNLTN---------DRYLATLTVRNLVG 407
NGKI++Y + + ++ + ++N T + + RY + +G
Sbjct 4549 RTNGKIINYTLFVREMFEGKTRAMSINTTHSSFGTRSLTVKHLKPFHRYEVRVQACTALG 4608
Query 408 KSDAAVLTIPACDFQA---THPVMDL-KAFPKDNMLWVEWTTPRESVKKYIL---EWCVL 460
+ + + + P +++ A + W I+ +
Sbjct 4609 CTSSEWTSTQTSEVPPLRQPAPHLEVQTATGGFQPIVAVWWAGPLQPNGKIICFELYRRQ 4668
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS 520
P + R+++ L Y V V + G + + APP
Sbjct 4669 VAAWPGTSSSLLIYNGSFRSFMDSELLPFTEYEYQVWAVNSAGKAASNWTRCRTGPAPPE 4728
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH---TEY 577
V AV+ NG I + +F N + +V S T+
Sbjct 4729 GLQAPTFHTVSSTRAVVNISV--PSRPNGNISLFRVF-----SNSSGTHVTLSEGTATQQ 4781
Query 578 TLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTT----PKF-AQGEIEAIVVPVCLAFLL 631
TL L+ T Y + + A T GP T P + +++ + +
Sbjct 4782 TLHDLSPFTTYTIGVEACTCFNCCSRGPTAELRTHPAPPSGLSPPQVQTLGSRMASVHWT 4841
Query 632 TTLL--GVLFCFNKRDLIKKHIWPN-VPD--PSKSHIAQWSP 668
LL GV+ + + +++ P+ P PS + W P
Sbjct 4842 PPLLPNGVIHSYELQ--LQRACPPDSAPRCPPSHTERKYWGP 4881
Score = 133 bits (335), Expect = 3e-30, Method: Composition-based stats.
Identities = 88/483 (18%), Positives = 153/483 (32%), Gaps = 69/483 (14%)
Query 135 IVNEGKKMRCEWDGGR-ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN 193
V + W +TL + + + T +D S
Sbjct 1060 WVQSSSTINVSWSPPECPNAHWLTYTLFRN--GSEIYTTEDEHPYYTQYFLDTSLSPHTA 1117
Query 194 IEVWVEAENALGKVTSDHINFDPVYKVKPNPPH---NLSVINSEELSSILKLTWTNPSIK 250
++E N V S + +Y+ KP NL+ S + LTWT S
Sbjct 1118 YSYYIETSN----VHSSTRSIPVIYETKPEVSEGHLNLT-HIIPVGSDSITLTWTGLSNS 1172
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
S + KY + D++ P +S T+ +L PFT+Y F ++ + Y
Sbjct 1173 SDPVAKYVLSCTPVDSTE----PCVSYEGPETSATIWNLVPFTQYCFSVQGCTNESCFY- 1227
Query 311 SDWSEEASGITYEDRPSK-APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
S T + P P +KI P+ +++ W PP ++NG I+ YE+
Sbjct 1228 ---SLPIIVTTAQAPPQTQGPPTVWKISPT------ELRIEWS--PPVDSNGIIISYELY 1276
Query 370 LTRW---------------KSHLQNYTVN-----------ATKLTVNLTNDRYLATLTVR 403
+ RW SH +VN +T ++ + Y +
Sbjct 1277 MRRWLSTEESLVFESHGLVSSHSALQSVNPSKNLLQQPQASTFISGLEPHTEYAFRVLAV 1336
Query 404 NLVGKSDAAVLTIPACDFQAT--HPVMDLKAFPKDNMLWVEWTTPRES-VKKYILEWCV- 459
N+ G+ +A + + P P L V W P E+ + I+ + +
Sbjct 1337 NMAGRVSSAWASERTGESVPVFMAPPSVSPLSPHS--LSVSWEKPAENFTRGEIIGYKIS 1394
Query 460 -------LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
L D + + ++Y+ L + Y TV+ + G +
Sbjct 1395 MVSEHFPLHDVPVMCSKMVHFAKSQDQSYIVRGLEPYRTYSFTVSLCDSVGCVTSALGSG 1454
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS 572
A P++ V + W LP NG Y + + V
Sbjct 1455 QTLAAAPAQLRPPMVTGVNSTTVHIRW--LPPAGVNGPPPLYHLERKKSSLPAATAAVTK 1512
Query 573 SHT 575
Sbjct 1513 GTR 1515
Score = 131 bits (330), Expect = 1e-29, Method: Composition-based stats.
Identities = 87/536 (16%), Positives = 148/536 (28%), Gaps = 52/536 (10%)
Query 119 TIISGLPPEKPKNL---SCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCK 173
+ +PP P L ++ W + + L+ +
Sbjct 2416 PVSVEMPPGAPDGLLSPRLAAAAPTSLQVVWSTPARNNAPGSPRYQLQMRPGPSTHGRLE 2475
Query 174 AKRDTPTSCTVDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
S + + + F E + A N G S KP P +IN
Sbjct 2476 LFPIPSASLSYEVTGLQPFTVYEFRLVATNGFGTAYSAWTPLMTTED-KPGPIDAPILIN 2534
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
+ +L + W P+ + I YNI + + +++TV L P+
Sbjct 2535 V--KARMLSVIWRQPAKCNGAITHYNIYLHGR--------LYLTVSGRVTNYTVVPLHPY 2584
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGIT--YEDRPSKA--PSFWYKIDPSHTQGYRTVQ 348
Y F++ G S SE + E PS P I +
Sbjct 2585 KAYHFQVEACTSQGCSK-SPSSETVWTLPGNPEGIPSPQLFPYTPTSIIVTWQPSAHLDL 2643
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG- 407
LV GK + +T +S + N L RY + L G
Sbjct 2644 LVENVTIERRVKGKKEVRNL-VTLARSQAMKFIDNDPAL---RPWTRYEYRVLGSTLDGG 2699
Query 408 --KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAP 465
S +T C P P + + V W P IL + + P
Sbjct 2700 TNSSAWVEVTTRPCRPSGVQPPTVRVLAP--DTVEVSWKAPL-MQNGDILSYEIRM---P 2753
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA-----DGPGSPESIKAYLKQAPPS 520
++ ++L +L Y +T+ G A APP
Sbjct 2754 EPLIKMTNMSSIMLSHLVKHLIPFTNYSVTIVACSGGNGYLAGCTESPPTLATTHPAPPQ 2813
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY----------RTIIGNETAVNV 570
+ + + +++ + W P NG Y + N
Sbjct 2814 ELAPLSVILLSESDVGISWQ--PPSKPNGPNLRYELLRCKIQQPLASNPPEDLNLWHNIY 2871
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVC 626
+ Y L+ T Y ++ + G E T TT + + +
Sbjct 2872 SGTRWFYKDKGLSRFTTYEYKLFVHNSVGFTPSREVTVTTLAGSPERGATVTASIL 2927
Score = 127 bits (319), Expect = 3e-28, Method: Composition-based stats.
Identities = 75/380 (20%), Positives = 125/380 (33%), Gaps = 35/380 (9%)
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
SF +DLKP T Y +RI G+G+ S+ T ED P + +
Sbjct 3449 NTHSFIDRDLKPSTVYEYRISAWNSYGRGF----SQSVRASTREDVPEGVKAPRWARTGK 3504
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT 399
H + L W+ P ++NG I+ Y + + Q ++ T Y
Sbjct 3505 HED---VIFLQWEE--PMQSNGPIIHYIL-FRDGRERFQGTALSFTDTQGIQPLQEYSYQ 3558
Query 400 LTVRNLVG-KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWC 458
L G V+ P ++ A + L + W+ P + K I +
Sbjct 3559 LKACTAAGCAVSCKVVAATTQRSPENVPPPNITAQSSET-LHLSWSVPEKM-KDAIKAYQ 3616
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ D I D + R + L Y T+ + G S E QA
Sbjct 3617 LWLDGKGLIYT----DTSDRRQHTVTGLQPYTNYSFTLAVCTSVGCTSSEPCVGQTLQAA 3672
Query 519 PSKG-PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT-E 576
P T R + L W+ P + NG I Y + N + + V
Sbjct 3673 PQGVWVTPRHIIINSTTVELYWN--PPERPNGLISQY-----QLRRNGSLLLVGGRDNQS 3725
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLG 636
+T S+L + Y+ ++ A T G ++ P + +I P C +
Sbjct 3726 FTDSNLEPGSRYIYKLEARTGGGSSWSEDYLVQMPLWTPEDIH----PPCN-VTVLGSDS 3780
Query 637 VLFCFNKRDLIKKHIWPNVP 656
+ + + P +P
Sbjct 3781 IFVAWPTPGNLL----PKIP 3796
Score = 126 bits (316), Expect = 6e-28, Method: Composition-based stats.
Identities = 64/424 (15%), Positives = 113/424 (27%), Gaps = 51/424 (12%)
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ SS + ++W+ P + L Y + ++ S E T+ F L P T
Sbjct 1062 QSSSTINVSWSPPECPNAHWLTYTLF---RNGSEIYTTEDEHPYYTQY-FLDTSLSPHTA 1117
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y + I S S T + + + I G ++ L W L
Sbjct 1118 YSYYIETSNVHS----STRSIPVIYETKPEVSEGHLNLTHIIPV----GSDSITLTWTGL 1169
Query 355 PPFEANGKILDYEVTLTRWKSHLQ----NYTVNATKLTVNLTNDRYLATLTVRNLVG--K 408
+ Y ++ T S + + + +Y ++
Sbjct 1170 SNSSD--PVAKYVLSCTPVDSTEPCVSYEGPETSATIWNLVPFTQYCFSVQGCTNESCFY 1227
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES---VKKYILEWCVLSDKAP 465
S ++T Q P K P L +EW+ P +S + Y L
Sbjct 1228 SLPIIVTTAQAPPQTQGPPTVWKISP--TELRIEWSPPVDSNGIIISYELYMRRWLSTEE 1285
Query 466 CITDWQQEDGTVHRTYLRGN-----------------LAESKCYLITVTPVYADGPGSPE 508
+ + H N L Y V V G S
Sbjct 1286 SLVFESHGLVSSHSALQSVNPSKNLLQQPQASTFISGLEPHTEYAFRVLAVNMAGRVSSA 1345
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV 568
++ P + + + W++ + G I Y I + V
Sbjct 1346 WASERTGESVPVFMAPPSVSPLSPHSLSVSWEKPAENFTRGEIIGYKISMVSEHFPLHDV 1405
Query 569 NV---------DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE 619
V S Y + L Y ++ G + T A ++
Sbjct 1406 PVMCSKMVHFAKSQDQSYIVRGLEPYRTYSFTVSLCDSVGCVTSALGSGQTLAAAPAQLR 1465
Query 620 AIVV 623
+V
Sbjct 1466 PPMV 1469
Score = 121 bits (304), Expect = 2e-26, Method: Composition-based stats.
Identities = 73/474 (15%), Positives = 142/474 (30%), Gaps = 42/474 (9%)
Query 170 ADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS 229
+ D T +D E + A N+ G+ S + V P +
Sbjct 3440 EEIVHSGDVNTHSFIDRDLKPSTVYEYRISAWNSYGRGFSQSVRASTREDV----PEGVK 3495
Query 230 V---INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 286
+ + ++ L W P + I+ Y + +D Q T+
Sbjct 3496 APRWARTGKHEDVIFLQWEEPMQSNGPIIHYILF---RDGRERFQGTALSFTDTQ----- 3547
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
++P EY ++++ G + + E+ P P+ Q T
Sbjct 3548 -GIQPLQEYSYQLKACTAAGCAVSCKVVAATTQRSPENVP--PPNI-------TAQSSET 3597
Query 347 VQLVWKTLPPFEANGKILDYEVTL-TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNL 405
+ L W P + I Y++ L + + +T Y TL V
Sbjct 3598 LHLSWSV--PEKMKDAIKAYQLWLDGKGLIYTDTSDRRQHTVTGLQPYTNYSFTLAVCTS 3655
Query 406 VG-KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
VG S + V + + W P E I ++ + + +
Sbjct 3656 VGCTSSEPCVGQTLQAAPQGVWVTPRHIIINSTTVELYWNPP-ERPNGLISQYQLRRNGS 3714
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK-QAPPSKGP 523
+ G ++++ NL Y+ + G E + P P
Sbjct 3715 LLL-----VGGRDNQSFTDSNLEPGSRYIYKLEARTGGGSSWSEDYLVQMPLWTPEDIHP 3769
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLT 583
+G + + W + + Y+I +V + + L +L+
Sbjct 3770 PCNVTVLGSDSIFVAWPTPGNLLPKIPV-EYSILLSGGSVTLLVFSVRHRQSAH-LKNLS 3827
Query 584 SDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGV 637
T Y +R+ A + G P T + A ++P L L ++ + V
Sbjct 3828 PFTQYEIRIQACQNGGCGVSPGTYVRTLEAAP----VGLMPPLLKALGSSCIEV 3877
Score = 117 bits (293), Expect = 3e-25, Method: Composition-based stats.
Identities = 66/401 (16%), Positives = 126/401 (31%), Gaps = 50/401 (12%)
Query 182 CTVDYSTVYFVNIEVWVEAENA-----LGKVTSDHINFDPVYKVKPNPPH---NLSVINS 233
+ + F N V + A + G S + P PP LSVI
Sbjct 2768 SHLVKHLIPFTNYSVTIVACSGGNGYLAGCTESPPT----LATTHPAPPQELAPLSVILL 2823
Query 234 EELSSILKLTWTNPSIKSVIILKYNI-QYR---------TKDASTWSQIPPEDTASTRSS 283
E + ++W PS + L+Y + + + +D + W I + TR
Sbjct 2824 SESD--VGISWQPPSKPNGPNLRYELLRCKIQQPLASNPPEDLNLWHNIY----SGTRWF 2877
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+ + L FT Y +++ G S E + T P + +
Sbjct 2878 YKDKGLSRFTTYEYKLFVHNSVGF----TPSREVTVTTLAGSPERG-----ATVTASILN 2928
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV---NLTNDRYLATL 400
+ + + WK + G + Y + + S V N Y L
Sbjct 2929 HTAIDVRWKKPTFQDLQGDVEYYTLFWSSGTSEESLKIFPDVDFHVIGQLSPNVEYQVFL 2988
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
V N V ++ V+ + + + + + V WT+P V+
Sbjct 2989 LVFNGVHAINSTVVHVTMWEEEPQGMLPPEVVIINSTAVRVIWTSPSNPN-------AVV 3041
Query 461 SDKAPCITDWQQEDGT-VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
++ + + + + GT +++ +L+ Y I V D + + P
Sbjct 3042 TESSVYVNNKLYKTGTDAPGSFVLEDLSPFTIYDIQVEVCTKDACVKSNGTQVSTAEDTP 3101
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
S + + ++W NG I Y + +T
Sbjct 3102 SDISIPVIRGITSRSLQIDWTT--PANPNGIILGYDVLRKT 3140
Score = 73.7 bits (179), Expect = 7e-12, Method: Composition-based stats.
Identities = 32/157 (20%), Positives = 58/157 (37%), Gaps = 11/157 (7%)
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV-RTKKVGKN 533
G+ Y G L YL VT + G S + + P PT R + + +
Sbjct 1902 GSQQSVYESG-LQPFTEYLYRVTASHEGGAVSSDWSRGRTLGTAPQSVPTPSRAQSINGS 1960
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFY------RTIIGNETAVNVDSSHTEYTLSSLTSDTL 587
+ W++ V G + Y + + + + + D+S L L
Sbjct 1961 SVEVAWNEPAVVK--GVLEKYVLKAYSEDSSQPRVPSASTELHDTSTHSGVLIGLHPFHS 2018
Query 588 YMVRMAAYTDEGGKDGPE-FTFTTPKFAQGEIEAIVV 623
Y V + A + G + + + +TP+ A E++A V
Sbjct 2019 YTVTLTACSRAGCTESSQALSISTPQEAPQEVQAPVA 2055
Score = 71.4 bits (173), Expect = 4e-11, Method: Composition-based stats.
Identities = 55/291 (19%), Positives = 100/291 (34%), Gaps = 35/291 (12%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLET---NFTLKSEWATHKFADCKA 174
+T ++G PE+ ++ + + W L+ +TL T +
Sbjct 2909 VTTLAG-SPERGATVTASILNHTAIDVRWKKPTFQDLQGDVEYYTLFWSSGTSEE---SL 2964
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN--PPHNLSVIN 232
K V V +V++ N + + S ++ + PP + +
Sbjct 2965 KIFPDVDFHVIGQLSPNVEYQVFLLVFNGVHAINSTVVHVTMWEEEPQGMLPPEVVII-- 3022
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
S+ +++ WT+PS + ++ T+ + + + SF ++DL PF
Sbjct 3023 ---NSTAVRVIWTSPSNPNAVV--------TESSVYVNNKLYKTGTDAPGSFVLEDLSPF 3071
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
T Y ++ +D S T ED PS I R++Q+ W
Sbjct 3072 TIYDIQVEVCTKDACVK----SNGTQVSTAEDTPSD-----ISIPVIRGITSRSLQIDWT 3122
Query 353 TLPPFEANGKILDYEVTLTRWK--SHLQNYTVNATKLTVNLTNDRYLATLT 401
T P NG IL Y+V W+ S Q T +Y +
Sbjct 3123 T--PANPNGIILGYDVLRKTWRPCSETQKLTDKPRDELCKAVKCQYPGKVC 3171
Score = 64.5 bits (155), Expect = 5e-09, Method: Composition-based stats.
Identities = 29/197 (15%), Positives = 56/197 (28%), Gaps = 5/197 (3%)
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD 462
+ G S V + C + + + V W+ P E + L + + +
Sbjct 1031 TCVPGASHLDVNNLLGCSKTPSQQPPPRGWVQSSSTINVSWSPP-ECPNAHWLTYTLFRN 1089
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+ T + L +L+ Y + + K
Sbjct 1090 GSEIYTTEDEHPYYTQYF-LDTSLSPHTAYSYYIETSNVHSSTRSIPVIYETKPEVSEGH 1148
Query 523 PTVR-TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS 581
+ VG + L W L + Y + + E V+ + T T+ +
Sbjct 1149 LNLTHIIPVGSDSITLTWTGLSNSSD--PVAKYVLSCTPVDSTEPCVSYEGPETSATIWN 1206
Query 582 LTSDTLYMVRMAAYTDE 598
L T Y + T+E
Sbjct 1207 LVPFTQYCFSVQGCTNE 1223
Score = 43.7 bits (101), Expect = 0.011, Method: Composition-based stats.
Identities = 53/298 (18%), Positives = 94/298 (32%), Gaps = 38/298 (13%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
PS+ P R + + W P + N YT+F T +
Sbjct 1051 PSQQPPPRGWVQSSSTINVSWS--PPECPNAHWLTYTLFRNGSEIYTTEDEHPYYTQYFL 1108
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDG-PEFTFTTPKFAQGEIEAI-VVPVCLAFLLTTLLG 636
+SL+ T Y + P T P+ ++G + ++PV + T G
Sbjct 1109 DTSLSPHTAYSYYIETSNVHSSTRSIPVIYETKPEVSEGHLNLTHIIPVGSDSITLTWTG 1168
Query 637 -----------VLFCFN----------KRDLIKKHIWPNVPDPSKSHIAQ-------WSP 668
VL C + IW VP Q +
Sbjct 1169 LSNSSDPVAKYVLSCTPVDSTEPCVSYEGPETSATIWNLVPFTQYCFSVQGCTNESCFYS 1228
Query 669 HTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPED--LKSLDLFKKEKINTEGHSS 726
+ Q +S E+ P + + S +L+ + ++TE S
Sbjct 1229 LPIIVTTAQAPPQTQGPPTVWKISPTELRIEWSPPVDSNGIIISYELYMRRWLSTE--ES 1286
Query 727 GIGGSSCMSSSRPSISSSDENES--SQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSES 782
+ S + SS ++ S + +++ Q +ST H+ Y +V +V + R S
Sbjct 1287 LVFESHGLVSSHSALQSVNPSKNLLQQPQASTFISGLEPHTEYAFRVLAVNMAGRVSS 1344
Score = 38.3 bits (87), Expect = 0.51, Method: Composition-based stats.
Identities = 27/175 (15%), Positives = 50/175 (29%), Gaps = 19/175 (11%)
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
GN++ + S S L T Y+ R+ A + G T A +
Sbjct 1891 CGGNDSILVYRGSQQSVYESGLQPFTEYLYRVTASHEGGAVSSDWSRGRTLGTAPQSVPT 1950
Query 621 IVVPVCLAFLLT--------TLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPP 672
+ + GVL + + + P VP A H
Sbjct 1951 PSRAQSINGSSVEVAWNEPAVVKGVLEKYVLKAYSEDSSQPRVP------SASTELHDTS 2004
Query 673 RHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSG 727
H+ + F + V + A + E ++L + ++ E +
Sbjct 2005 THSGV----LIGLHPFHSYT-VTLTACSRAGCTESSQALSISTPQEAPQEVQAPV 2054
>sp|P54296|MYOM2_HUMAN Myomesin-2 OS=Homo sapiens OX=9606 GN=MYOM2
PE=1 SV=3
Length=1465
Score = 206 bits (524), Expect = 2e-53, Method: Composition-based stats.
Identities = 109/637 (17%), Positives = 192/637 (30%), Gaps = 77/637 (12%)
Query 41 HSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTII--NRTASSVTFTDIASLN 98
T C + W + + + ++T + +S++F+ + +
Sbjct 292 GETVTLKCTM--LVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDD 349
Query 99 IQ-LTCNILTFGQLEQN-----VYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRET 152
T I++ G + + V + P P +L C + W T
Sbjct 350 EGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTT 409
Query 153 HLET---NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV--NIEVWVEAENALGKV 207
F + E T+ + C D P T F + V A N+ G
Sbjct 410 TESPVMGYFVDRCEVGTNNWVQC---NDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGIS 466
Query 208 TS----------DHINFDPVYKVK--------------------PNPPHNLSVINSEELS 237
D ++ + V P PP V SE
Sbjct 467 RPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPT--GVHASEISR 524
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ + L+W P+ + L Y I+ + +W ++ + TA + V DL YVF
Sbjct 525 NYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQ-TAVRSPRYAVFDLMEGKSYVF 583
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK-TLPP 356
R+ G S+ + PS + +V + W
Sbjct 584 RVLSANRHGLSEPSEITSPIQAQDVTVVPSAP-----GRVLASRNTKTSVVVQWDRPKHE 638
Query 357 FEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAA-- 412
+ G +D V T + + + V+ T ++Y+ + N VG S+ +
Sbjct 639 EDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQE 698
Query 413 ---VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITD 469
+ A + + L +M + W P+ S IL + L + +
Sbjct 699 SDVIKVQAALTVPSHPYGITLLNCDGHSMT-LGWKVPKFSGGSPILGYY-LDKREVHHKN 756
Query 470 WQ--QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS---PESIKAYLKQAPPSKGP- 523
W + L E Y + V G G P P GP
Sbjct 757 WHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPA 816
Query 524 -TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAVNVDSSHTEY-TLS 580
+ +V V+ W PV + + Y + +R G VN ++ + Y +S
Sbjct 817 YDLTFCEVRDTSLVMLWKA-PVYSGSSPVSGYFVDFREEDAGEWITVNQTTTASRYLKVS 875
Query 581 SLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQG 616
L Y+ R+ A G GK + G
Sbjct 876 DLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPG 912
Score = 99.5 bits (246), Expect = 7e-20, Method: Composition-based stats.
Identities = 55/267 (21%), Positives = 94/267 (35%), Gaps = 21/267 (8%)
Query 70 NHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKP 129
NH I ++ + T + ++N + + + P P
Sbjct 660 NHKPIGYNRFVVHGLTTGEQYIFRVKAVNAV--GMSENSQESDVIKVQAALTV---PSHP 714
Query 130 KNLSCIVNEGKKMRCEWDGGRETH---LETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
++ + +G M W + + + + K E + + + PT TVD
Sbjct 715 YGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDG 774
Query 187 STVYFVNIEVWVEAENALG----KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
T E + A N G S+H + +P P ++L+ E + L +
Sbjct 775 LTEG-SLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLT--FCEVRDTSLVM 831
Query 243 TWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
W P S + Y + +R +DA W + T + V DL+ YVFR+R
Sbjct 832 LWKAPVYSGSSPVSGYFVDFREEDAGEWITVN--QTTTASRYLKVSDLQQGKTYVFRVRA 889
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSK 328
+ +G G SD SE E RP
Sbjct 890 VNANGVGKPSDTSEPVLV---EARPGT 913
>sp|P32004|L1CAM_HUMAN Neural cell adhesion molecule L1 OS=Homo
sapiens OX=9606 GN=L1CAM PE=1 SV=2
Length=1257
Score = 205 bits (520), Expect = 6e-53, Method: Composition-based stats.
Identities = 76/409 (19%), Positives = 140/409 (34%), Gaps = 31/409 (8%)
Query 215 DPVYKVKPNPPHNLSVINSEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
+ P P L + + L+ S ++++W+ + I KY+I++ K+ +
Sbjct 605 QLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYS 664
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
++S T+ L P+ Y FR+ + + G G S SE + +T E P K P
Sbjct 665 LGKVPGNQTSTTL-KLSPYVHYTFRVTAINKYGPGEPSPVSE--TVVTPEAAPEKNP--- 718
Query 334 YKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVTLTR--WKSHLQNYTVNATKLTVN 390
+D T + + WK L + N + Y V + Q V+ L V+
Sbjct 719 --VDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVS 776
Query 391 LTND--RYLATLTVRNLVGKSDAAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
T+ Y + N GK +TI D+ P ++ + + V+W
Sbjct 777 NTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPV 836
Query 447 -----RESVKKY-ILEWCVLSDKAPCITDWQQ---EDGTVHRTYLRGNLAESKCYLITVT 497
+ ++ Y + W S + + + + L Y + V
Sbjct 837 DLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQ 896
Query 498 PVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
G G + P + + +L W P NG + Y +
Sbjct 897 AFNGRGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLS 954
Query 558 YRTII----GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
Y + G + D + L+ L+ Y ++ A T EG +
Sbjct 955 YHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGE 1003
Score = 164 bits (415), Expect = 5e-40, Method: Composition-based stats.
Identities = 119/710 (17%), Positives = 224/710 (32%), Gaps = 88/710 (12%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P S + + S T C + I W+ + + + +
Sbjct 524 PRSTIEKKGSRVTFTCQ-----ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLV- 577
Query 93 DIASLNIQLTCNILTFGQLEQNVYGIT---IISGLPPEKPKNLSCIVN--EGKKMRCEWD 147
I SL+ N E +V ++ G P P+ + ++ ++R W
Sbjct 578 -IHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 636
Query 148 GGRETHLET-NFTLKSEW---ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENA 203
+ + + ++ E A K+ TS T+ S +V+ V A N
Sbjct 637 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSP--YVHYTFRVTAINK 694
Query 204 LGKVTSDHINFDPVYKVKPNP-PH--NLSVINSEELSSILKLTWTNPSIK--SVIILKYN 258
G ++ V P P + V ++ + +TW + ++Y
Sbjct 695 YGPGEPSPVS---ETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYR 751
Query 259 IQYRTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
+Q+R + W + D V + F Y +++ + GKG +
Sbjct 752 VQWRPQGTRGPWQEQIVSDPF-----LVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGY 806
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL 377
SG ED P P ++ V + W+ + + G + Y VT R S
Sbjct 807 SG---EDYPQAIPE----LEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQR 859
Query 378 QNY-----------TVNATK--LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
++ N T L+ Y + N G A+ T +
Sbjct 860 KHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPG 919
Query 425 HPVMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
HP + L + W P + Y+L + L + + D + RT+
Sbjct 920 HPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPEL-RTH 978
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
+L+ Y + +GPG + + G+N +V+ W
Sbjct 979 NLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGENYSVVSW-- 1036
Query 542 LPVDVQNGFIRNYTIFYRTIIGNETAVN-----VDSSHTEYTLSSLTSDTLYMV-----R 591
+P + Q F + I ++ + + + V + + YT L DT Y + R
Sbjct 1037 VPKEGQCNF--RFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHLFKER 1094
Query 592 MAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHI 651
M + +G P + V A +L L+ ++ CF KR
Sbjct 1095 MFRHQMAVKTNGTGR-VRLPPAGFATEGWFIGFVS-AIILLLLVLLILCFIKR------- 1145
Query 652 WPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDK 701
S ++S +S+ + D F + +E + +K
Sbjct 1146 ---------SKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEK 1186
>sp|Q90478|L1CA1_DANRE Neural cell adhesion molecule L1.1 (Fragment)
OS=Danio rerio OX=7955 GN=nadl1.1 PE=2 SV=1
Length=1197
Score = 204 bits (518), Expect = 1e-52, Method: Composition-based stats.
Identities = 100/571 (18%), Positives = 200/571 (35%), Gaps = 54/571 (9%)
Query 63 NYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIIS 122
I W+ I T S+ ++++ + ++ + +
Sbjct 391 PKIHWEILDSIPALSNAKISQTTNGSLKISNVSEEDSNRYTCSVSETNKSISADVEVLNR 450
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSC 182
P+NL I + C++ H + T++ HK D
Sbjct 451 TKIVGPPQNLHVIRGSDAILHCKY---TVDHNLKSPTVQWNKDGHKIT-ASTSNDKYHEI 506
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
+ ++ + + + SD + + KP+PP +L + SE++ + +
Sbjct 507 EGSLKVLDVQMEDMGIYSCEVSTTLDSDTASGYITVQDKPDPPQSLKL--SEKMERSVTI 564
Query 243 TWTNPSIKSVIILKYNIQYR---TKDASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVF 297
+W + + +Y I+ T D W + +D S RS + +++Y F
Sbjct 565 SWMPSVENNSPVTEYVIEMNEGETPDEGQWQKYRSVSQDIDSWRSICS------YSKYHF 618
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
+IR + G ++ S S T +P P + + +++ + W+ +
Sbjct 619 QIRAVNSIGTSAPTESS--LSYSTPAAKPDTNPENVMTL----STDPKSMIISWQEMDRR 672
Query 358 EANGKILDYEVTLTRWK---SHLQNYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAA 412
+ NG Y+V R +H +V+ L VN T + + N +G +
Sbjct 673 QFNGPGFQYKVFWRRAADSGAHWTESSVSNPPLMVNNTGTFVSFEIKVQAVNDLGAAPEP 732
Query 413 VLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTP-RESVKKYILEWCVLSDKAPCITD 469
+ I DF P + + V W+ ESV+ ++L + +
Sbjct 733 LTVIGYSGEDFPLEAPSALSVTELQKTSVMVRWSPVRPESVRGHLLGYKIYLRMKGS--Q 790
Query 470 WQQEDGTVHRT--------------YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
W+ V + + +L Y +T+T + G G
Sbjct 791 WETPGRAVSSSGNPTVIEVPADAAEKIVSDLQFYSDYTLTITAFNSKGEGPHSEESFSTP 850
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT-IIGNETAVNVDSSH 574
+ P + ++E L W+ NG IR Y + Y+ +IG+E+ +V+S
Sbjct 851 EGAPGPVLFLPFDSPSESEITLRWEA--PHKPNGEIRGYLLQYQEVVIGSESPQHVESID 908
Query 575 ----TEYTLSSLTSDTLYMVRMAAYTDEGGK 601
TE+TL +L ++ Y ++A D G
Sbjct 909 LPAVTEFTLKNLNPESRYTFHLSARNDAGDG 939
Score = 163 bits (411), Expect = 1e-39, Method: Composition-based stats.
Identities = 99/699 (14%), Positives = 226/699 (32%), Gaps = 79/699 (11%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRT-ASSVTF 91
P++ V S+ C ++ + + W + I S+
Sbjct 457 PQNLHVIRGSDAILHCKY----TVDHNLKSPTVQWNKDGHKITASTSNDKYHEIEGSLKV 512
Query 92 TDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRE 151
D+ ++ + ++ G I P+ P++L + + W E
Sbjct 513 LDVQMEDMGIYSCEVSTTLDSDTASG-YITVQDKPDPPQSLKLSEKMERSVTISWMPSVE 571
Query 152 THLE-TNFTLKSEWATHKFADCKAKRDTPTSCTVDY--STVYFVNIEVWVEAENALGKVT 208
+ T + ++ + + ++ S +D S + + A N++G
Sbjct 572 NNSPVTEYVIEMN-EGETPDEGQWQKYRSVSQDIDSWRSICSYSKYHFQIRAVNSIGTSA 630
Query 209 SDHINFD-PVYKVKPNP-PHNLSVINSEELSSILKLTWT--NPSIKSVIILKYNIQYRTK 264
+ KP+ P N+ ++++ S I+ +W + + +Y + +R
Sbjct 631 PTESSLSYSTPAAKPDTNPENVMTLSTDPKSMII--SWQEMDRRQFNGPGFQYKVFWRRA 688
Query 265 --DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI-- 320
+ W++ + V + F + +++ + + G E + I
Sbjct 689 ADSGAHWTESSVSN-----PPLMVNNTGTFVSFEIKVQAVNDLGAAP-----EPLTVIGY 738
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT----RWKSH 376
+ ED P +APS + T +V + W + P G +L Y++ L +W++
Sbjct 739 SGEDFPLEAPSALSVTELQKT----SVMVRWSPVRPESVRGHLLGYKIYLRMKGSQWETP 794
Query 377 LQNYTVNATKLTVNLTNDR-------------YLATLTVRNLVGKSDAAVLTIPACDFQA 423
+ + + + + D Y T+T N G+ + + +
Sbjct 795 GRAVSSSGNPTVIEVPADAAEKIVSDLQFYSDYTLTITAFNSKGEGPHSEESFSTPEGAP 854
Query 424 THPVMDLKAFPKDNMLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ P ++ + + W P + ++ Y+L++ + + + D
Sbjct 855 GPVLFLPFDSPSESEITLRWEAPHKPNGEIRGYLLQYQEVVIGSESPQHVESIDLPAVTE 914
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
+ NL Y ++ G G+P + P+V G+ L W
Sbjct 915 FTLKNLNPESRYTFHLSARNDAGDGAPAIQSGAT--LLDGEPPSVINMTAGETSVNLSWV 972
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
GF Y E+ ++S+ Y L L S +Y +++ +
Sbjct 973 PGDRHRNLGFSFRYLKKIEGAEWEESE-KINSTQAFYQLQGLDSGVIYHLQVLSGNT--S 1029
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLT----TLLGVLFCFNKRDLIKKHIWPNVP 656
D T +P++ + + + L+ +L C+ K
Sbjct 1030 YDWDFKTIYSPEWHKSPRNFATEGWFIGLISALVLLLLVLLLLCYIK------------- 1076
Query 657 DPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVE 695
KS ++S ++ +Q D F + +E
Sbjct 1077 ---KSKGGKYSVKDKEEGQGDAANQKLKDDAFGEYRSLE 1112
>sp|Q90374|PRLR_COLLI Prolactin receptor OS=Columba livia OX=8932
GN=PRLR PE=2 SV=1
Length=830
Score = 201 bits (511), Expect = 1e-52, Method: Composition-based stats.
Identities = 78/396 (20%), Positives = 141/396 (36%), Gaps = 36/396 (9%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWAT-HKFADCK-AKRDTPTSCT 183
P KPK + C E + C W G + L TN+TL + K +C P SC
Sbjct 28 PGKPKIIRCRSLEKETFSCWWKPGSDGGLPTNYTLFYSKDSEEKIYECPDYGMSGPNSCY 87
Query 184 VDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
D + + + V A N +G +SD D V+P+ P NLS+ S+ L
Sbjct 88 FDKNHTNPWTTYNITVMAMNEIGSNSSDPQYVDVTSIVQPDAPVNLSLETKTSASTTYLL 147
Query 243 -TWTNPSI----KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
W+ P + + + +Y ++ + ++ W + ++ + V L+ +YV
Sbjct 148 AKWSPPPLADVTSNSHVYRYELRLKPEEKEEWETVS----VGVQTQYKVNRLQAGVKYVV 203
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
++RC+ + G WS+WS E +P I + T WK P
Sbjct 204 QVRCVLDI--GEWSEWSSERHIHIPNGE---SPPEKPTIIKCRSPEKETFTCWWK---PG 255
Query 358 EANGKILDYEVTLTRWKS----HLQNYTVNATKLTVNLTN-----DRYLATLTVRNLVGK 408
G +Y + ++ +Y Y T+ N +G
Sbjct 256 SDGGHPTNYTLLYSKEGEERVYECPDYKTAGPNSCYFDKKHTSFWTIYNITVKATNEIGS 315
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNM-----LWVEWTTPRESVK--KYILEWCVLS 461
+ + L + T P +++ K + L + W+ P + ++ L
Sbjct 316 NVSDPLYVDVTYIVQTDPPVNVTLELKKTVNRKPYLVLTWSPPPLADVRSGWLTLDYELR 375
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
K +W+ Y +L K Y++ +
Sbjct 376 LKPEEAEEWETIFVGQQTHYKMFSLNPGKKYIVQIH 411
Score = 186 bits (473), Expect = 1e-47, Method: Composition-based stats.
Identities = 81/354 (23%), Positives = 141/354 (40%), Gaps = 30/354 (8%)
Query 20 STGELLDPCGYISPESPV-VQLHSNFTAVCVL---KEKCMDYFHVNANYIVWKTNHFTIP 75
S + +D + P++PV + L + +A K V +N V++ P
Sbjct 114 SDPQYVDVTSIVQPDAPVNLSLETKTSASTTYLLAKWSPPPLADVTSNSHVYRYELRLKP 173
Query 76 KEQY---TIINRTASSVTFTDIAS---LNIQLTCNILTFGQLEQ--NVYGITIISG-LPP 126
+E+ T+ + + + +Q+ C +L G+ + + I I +G PP
Sbjct 174 EEKEEWETVSVGVQTQYKVNRLQAGVKYVVQVRC-VLDIGEWSEWSSERHIHIPNGESPP 232
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWAT-HKFADCK-AKRDTPTSCTV 184
EKP + C E + C W G + TN+TL + +C K P SC
Sbjct 233 EKPTIIKCRSPEKETFTCWWKPGSDGGHPTNYTLLYSKEGEERVYECPDYKTAGPNSCYF 292
Query 185 DYSTVYFVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEELSSILK 241
D F + V+A N +G SD + D Y V+ +PP N++ + + L
Sbjct 293 DKKHTSFWTIYNITVKATNEIGSNVSDPLYVDVTYIVQTDPPVNVTLELKKTVNRKPYLV 352
Query 242 LTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
LTW+ P + V + L Y ++ + ++A W I ++ + + L P +Y+
Sbjct 353 LTWSPPPLADVRSGWLTLDYELRLKPEEAEEWETI----FVGQQTHYKMFSLNPGKKYIV 408
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
+I C D G WS+WS E D K W + + + + W
Sbjct 409 QIHCKP-DHHGSWSEWSLEKYLQIPTDFRIKDMVVWIIVGVLSSLIC--LVMSW 459
Score = 96.1 bits (237), Expect = 6e-19, Method: Composition-based stats.
Identities = 96/554 (17%), Positives = 172/554 (31%), Gaps = 54/554 (10%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P P + + E+ + W S + Y + Y + P +
Sbjct 27 YPGKPKIIRCRSLEKETFSCW--WKPGSDG-GLPTNYTLFYSKDSEEKIYECPDYGMSGP 83
Query 281 RSSFTVQD-LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
S + ++ P+T Y + M E G S+ S+ AP ++
Sbjct 84 NSCYFDKNHTNPWTTYNITVMAMNEIG----SNSSDPQYVDVTSIVQPDAP-VNLSLETK 138
Query 340 HTQGYRTVQLVWKTLPPFE--ANGKILDYEVTLT-RWKSHLQNYTVN-ATKLTVNLTNDR 395
+ + W P + +N + YE+ L K + +V T+ VN
Sbjct 139 TSASTTYLLAKWSPPPLADVTSNSHVYRYELRLKPEEKEEWETVSVGVQTQYKVNRLQAG 198
Query 396 YLATLTVRN--LVGK----SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES 449
+ VR +G+ S + IP + P + P+ W S
Sbjct 199 VKYVVQVRCVLDIGEWSEWSSERHIHIPNGESPPEKPTIIKCRSPEKETFTCWWKP--GS 256
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHR----TYLRGNLAESKCYLITVTPVYADGPG 505
+ + +L K ++ D + + + + Y ITV G
Sbjct 257 DGGHPTNYTLLYSKEGEERVYECPDYKTAGPNSCYFDKKHTSFWTIYNITVKATNEIGSN 316
Query 506 SPESIKAYLKQAPPSKGPTVRTKKVGKN-----EAVLEWDQLP-VDVQNGFIR-NYTIFY 558
+ + + + P T ++ K VL W P DV++G++ +Y +
Sbjct 317 VSDPLYVDVTYIVQTDPPVNVTLELKKTVNRKPYLVLTWSPPPLADVRSGWLTLDYELRL 376
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ--- 615
+ E T Y + SL Y+V++ D G ++ K+ Q
Sbjct 377 KPEEAEEWETIFVGQQTHYKMFSLNPGKKYIVQIHCKPD---HHGSWSEWSLEKYLQIPT 433
Query 616 -----GEIEAIVVPVCLAFLLTTL--LGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSP 668
+ I+V V + + + VL + I P VP P I
Sbjct 434 DFRIKDMVVWIIVGVLSSLICLVMSWTMVLKGYRMIAFIL----PPVPGPKIKGIDTHLL 489
Query 669 HTPPRHNFNSKDQMYSDGNFTDVSVVEIE--ANDKKPFPEDLKSLDL---FKKEKINTEG 723
T S + +D + IE + + + S D K K+ +
Sbjct 490 ETGKSEELLSALGCHGFPPTSDCEELLIEYLEVEDSEDQQLMPSHDNGHPSKNAKMIAKE 549
Query 724 HSSGIGGSSCMSSS 737
S G SC S S
Sbjct 550 TDSDSGRGSCDSPS 563
>sp|P43146|DCC_HUMAN Netrin receptor DCC OS=Homo sapiens OX=9606
GN=DCC PE=1 SV=2
Length=1447
Score = 204 bits (518), Expect = 1e-52, Method: Composition-based stats.
Identities = 96/610 (16%), Positives = 184/610 (30%), Gaps = 77/610 (13%)
Query 42 SNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQL 101
CV W I S++ +++ + +
Sbjct 256 DAVLECCV--------SGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGM 307
Query 102 TCNILTFGQLEQNVYGITIISGLPP---EKPKNLSCIVNEGKKMRCE----------WDG 148
++T+ + + +PP P NL + + C W
Sbjct 308 YTCVVTYKNENIS-ASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMK 366
Query 149 GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
+ + +++ + + + C AEN G
Sbjct 367 NGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCV----------------AENEAGNAQ 410
Query 209 SDHINFDP-----VYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT 263
+ P V P+ P + V+ S ++L+W P+ I + + +
Sbjct 411 TSAQLIVPKPAIPSSSVLPSAPRD--VVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSR 468
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+ + + T TV +LKP Y FR+ E G G + S+ T
Sbjct 469 EGDNRERALNT--TQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPG---ESSQPIKVATQP 523
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH-LQNYTV 382
+ P + + + ++ + W+ PP ANG + Y + T + QN V
Sbjct 524 ELQVPGP---VENLQAVSTSPTSILITWE--PPAYANGPVQGYRLFCTEVSTGKEQNIEV 578
Query 383 NATKLTVNLTN--DRYLATLTVRNLVGKSDAA--VLTIPACDFQATHPVMDLKAFPKDNM 438
+ + Y N G + + + D + P
Sbjct 579 DGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRS 638
Query 439 LWVEWTTPR-ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
+ V W P + +I + + K + + + YL L + Y V+
Sbjct 639 IKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLW-YLFTGLEKGSQYSFQVS 697
Query 498 PVYADGPGSPESIKAYLKQAP---------PSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
+ +G G P + Y + P P + ++ + N ++ W P N
Sbjct 698 AMTVNGTGPPSNW--YTAETPENDLDESQVPDQPSSLHVRPQT-NCIIMSW--TPPLNPN 752
Query 549 GFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFT 607
+R Y I Y V VDS Y++ L S + Y++ + A+ + G G E
Sbjct 753 IVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESA 812
Query 608 FTTPKFAQGE 617
T +
Sbjct 813 TTRSITDPTD 822
Score = 181 bits (458), Expect = 3e-45, Method: Composition-based stats.
Identities = 101/604 (17%), Positives = 194/604 (32%), Gaps = 80/604 (13%)
Query 42 SNFTAVCVLKEKCMDYFHVNANYIVWKTN-HFTIPKEQYTIINRTASSVTFTDIASLNIQ 100
+ C + K VN W N IP + + I+ + + + S
Sbjct 346 MDIEFECTVSGK--PVPTVN-----WMKNGDVVIPSDYFQIVGGSNLRILGV-VKSDEGF 397
Query 101 LTCNILTFGQLEQNVYGITI------ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRE--T 152
C Q + + S + P P+++ ++ + +R W E
Sbjct 398 YQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKG 457
Query 153 HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-TSDH 211
+++T FT+ + + V A N G +S
Sbjct 458 NIQT-FTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQP 516
Query 212 INFDPVYKVK-PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS 270
I +++ P P NL +++ + + +TW P+ + + Y +
Sbjct 517 IKVATQPELQVPGPVENLQAVST--SPTSILITWEPPAYANGPVQGYRLFCTEVSTGKEQ 574
Query 271 QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
I + S+ ++ LK FTEY R G G +D + + +T D PS P
Sbjct 575 NIEVDGL-----SYKLEGLKKFTEYSLRFLAYNRYGPGVSTD---DITVVTLSDVPSAPP 626
Query 331 SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN 390
R++++ W P NG I Y++ + + T+ L
Sbjct 627 QNVSL----EVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYL 682
Query 391 LT----NDRYLATLTVRNLVGKSDAA------VLTIPACDFQATHPVMDLKAFPKDNMLW 440
T +Y ++ + G + + Q L P+ N +
Sbjct 683 FTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTNCII 742
Query 441 VEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
+ WT P V+ YI+ + V S A + + R Y L S Y+I++
Sbjct 743 MSWTPPLNPNIVVRGYIIGYGVGSPYAETV-----RVDSKQRYYSIERLESSSHYVISLK 797
Query 498 PVYADGPGSP----ESIKAYLKQAPP---------------------SKGPTVRTKKVGK 532
G G P + ++ P V+ +
Sbjct 798 AFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLSTPMLPPVGVQAVALTH 857
Query 533 NEAVLEWDQ--LPVDVQNGFIRNYTIFYRTIIG-NETAVNVDSSHTEYTLSSLTSDTLYM 589
+ + W +P + + +R YT+ +RT + + D++ YT + L +T+Y
Sbjct 858 DAVRVSWADNSVPKNQKTSEVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYE 917
Query 590 VRMA 593
+
Sbjct 918 FSVM 921
Score = 170 bits (431), Expect = 5e-42, Method: Composition-based stats.
Identities = 90/544 (17%), Positives = 166/544 (31%), Gaps = 62/544 (11%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSE 163
N G+ Q + T P +NL + + W+ +
Sbjct 506 NEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQG--YRL 563
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKP 222
+ T + + F + A N G V++D I + V
Sbjct 564 FCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPS 623
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIK--SVIILKYNIQYRTKDASTWSQIPPEDTAST 280
PP N+S+ S +K++W P + I Y I++R E
Sbjct 624 APPQNVSLEVVN--SRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRG----EMETLEPN 677
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR--PSKAPSFWYKIDP 338
+ L+ ++Y F++ M +G G S+W + T E+ S+ P +
Sbjct 678 NLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNW---YTAETPENDLDESQVPDQPSSLHV 734
Query 339 SHTQGYRTVQLVWKTLPPFEAN----GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND 394
+ + W PP N G I+ Y V ++ + + ++
Sbjct 735 RPQTNC--IIMSW--TPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSS 790
Query 395 RYLATLTVRNLVGKS-------------------------DAAVLTIPACDFQATHPVMD 429
Y+ +L N G+ D ++P PV
Sbjct 791 HYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLSTPMLPPVGV 850
Query 430 LKAFPKDNMLWVEW---TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
+ + V W + P+ + + V + + + + T +Y L
Sbjct 851 QAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGL 910
Query 487 AESKCYLITVTPV-YADGPGSPESIKAYLKQAPPSKGP---TVRTKKVGKNEAVLEWDQL 542
+ Y +V + A +A P+ P TV T++ ++ W
Sbjct 911 KPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPRAVIVSWQ-- 968
Query 543 PVDVQNGFIRNYTIFYR----TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
P NG I Y +FY I + + + + L DT+Y R+ A +
Sbjct 969 PPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLNLDTMYYFRIQARNSK 1028
Query 599 GGKD 602
G
Sbjct 1029 GVGP 1032
Score = 138 bits (347), Expect = 7e-32, Method: Composition-based stats.
Identities = 72/326 (22%), Positives = 112/326 (34%), Gaps = 26/326 (8%)
Query 319 GITYEDRPSKA--PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
+ PS + PS + P R V+L W+ PP EA G I + V +R +
Sbjct 416 IVPKPAIPSSSVLPSAPRDVVPVLVSS-RFVRLSWR--PPAEAKGNIQTFTVFFSREGDN 472
Query 377 LQNYTVNATKLTVNLT------NDRYLATLTVRN--LVGKSDAAVLTIPACDFQATHPVM 428
+ ++ LT Y + N G+S + + Q PV
Sbjct 473 RERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVE 532
Query 429 DLKAFPKD-NMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
+L+A + + W P V+ Y L +S Q + L G
Sbjct 533 NLQAVSTSPTSILITWEPPAYANGPVQGYRLFCTEVSTGKE-----QNIEVDGLSYKLEG 587
Query 485 NLAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQL 542
L + Y + GPG S + I PS P V + V + W
Sbjct 588 -LKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPP 646
Query 543 PVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GK 601
P QNGFI Y I +R ++ ++ Y + L + Y +++A T G G
Sbjct 647 PSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGP 706
Query 602 DGPEFTFTTPKFAQGEIEAIVVPVCL 627
+T TP+ E + P L
Sbjct 707 PSNWYTAETPENDLDESQVPDQPSSL 732
Score = 121 bits (302), Expect = 2e-26, Method: Composition-based stats.
Identities = 77/446 (17%), Positives = 152/446 (34%), Gaps = 54/446 (12%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG---GRETHLETNFTL 160
N G ++ +T+ S +P P+N+S V + ++ W G + T + +
Sbjct 602 NRYGPGVSTDDITVVTL-SDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKI 660
Query 161 KSEWATHKFADCKAKRDTPTSC-TVDYSTVYFVNIEVWVEAENALGKVTSDHINF----- 214
+ T + + + P + + V A G +
Sbjct 661 RHRKTTRRG---EMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPE 717
Query 215 -DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
D P+ P +L V ++ + ++WT P ++++ Y I Y + +
Sbjct 718 NDLDESQVPDQPSSLHVRPQ---TNCIIMSWTPPLNPNIVVRGYIIGY-GVGSPYAETVR 773
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT-----------Y 322
S + ++++ L+ + YV ++ G+G S IT
Sbjct 774 ---VDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLL 830
Query 323 EDRPSKAPSFWYKIDP-----SHTQGYRTVQLVW--KTLPPFEANGKILDYEVTLTRWKS 375
+D P+ P + P + + V++ W ++P + ++ Y V S
Sbjct 831 DDFPTSVPDLSTPMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRTSFS 890
Query 376 HLQNY-TVNATKLTVNLT----NDRYLATLTVRNLVGKSDAAVLTIPAC-DFQATHPVMD 429
Y + + T L+ T N Y ++ V S ++ + T D
Sbjct 891 ASAKYKSEDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKD 950
Query 430 LKAFPKDN---MLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHR-TYL 482
L ++ + V W P E+ + YIL + + DK I DW E + R T+
Sbjct 951 LTVITREGKPRAVIVSWQPPLEANGKITAYILFYTL--DKNIPIDDWIMETISGDRLTHQ 1008
Query 483 RGNLAESKCYLITVTPVYADGPGSPE 508
+L Y + + G G
Sbjct 1009 IMDLNLDTMYYFRIQARNSKGVGPLS 1034
Score = 81.1 bits (198), Expect = 3e-14, Method: Composition-based stats.
Identities = 40/193 (21%), Positives = 66/193 (34%), Gaps = 9/193 (5%)
Query 128 KPKNLSCIVNEGKKMRCEW-DGGRETHLETN----FTLKSEWATHKFADCKAKRDTPTSC 182
P + + +R W D + +T+ +T++ W T A K K + TS
Sbjct 846 PPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVR--WRTSFSASAKYKSEDTTSL 903
Query 183 TVDYSTVY-FVNIEVWVEAE-NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
+ + + E V N S + + P +L+VI E +
Sbjct 904 SYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPRAV 963
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
++W P + I Y + Y E + R + + DL T Y FRI+
Sbjct 964 IVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLNLDTMYYFRIQ 1023
Query 301 CMKEDGKGYWSDW 313
G G SD
Sbjct 1024 ARNSKGVGPLSDP 1036
>sp|O00533|NCHL1_HUMAN Neural cell adhesion molecule L1-like protein
OS=Homo sapiens OX=9606 GN=CHL1 PE=1 SV=4
Length=1208
Score = 203 bits (516), Expect = 2e-52, Method: Composition-based stats.
Identities = 91/428 (21%), Positives = 156/428 (36%), Gaps = 40/428 (9%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST--WSQI 272
P+PP NL + SE + ++LTW + + I +Y +++ W ++
Sbjct 605 QVTVLDVPDPPENLHL--SERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRWEEL 662
Query 273 PPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF 332
T + L PF Y FR+ + E G+ S S+ T P + P
Sbjct 663 TRVQGKKTT---VILPLAPFVRYQFRVIAVNEVGRSQPSQPSD--HHETPPAAPDRNPQN 717
Query 333 WYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS--HLQNYTVNATKLTVN 390
+ + + W+ L E NG L+Y VT + + TV L V
Sbjct 718 IRV----QASQPKEMIIKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTNHTLRVM 773
Query 391 LT--NDRYLATLTVRNLVGKS--DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
Y + N +G +V D+ T PV+ ++ V W+T
Sbjct 774 TPAVYAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTV 833
Query 447 RES-----VKKYILEWC-----VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV 496
+ +K Y + W + P + + G + + L + +TV
Sbjct 834 PKDRVHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPS-LDAFSEFHLTV 892
Query 497 TPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYT 555
+ G G E + P + ++ KV K+ A L W NG + Y
Sbjct 893 LAYNSKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWGLPK--KLNGNLTGYL 950
Query 556 IFYRTI-----IGNETAVNVDS-SHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTF 608
+ Y+ I IG +N+ + S + LS+L + T Y + A T +G GK E +
Sbjct 951 LQYQIINDTYEIGELNDINITTPSKPSWHLSNLNATTKYKFYLRACTSQGCGKPITEESS 1010
Query 609 TTPKFAQG 616
T + ++G
Sbjct 1011 TLGEGSKG 1018
Score = 140 bits (352), Expect = 1e-32, Method: Composition-based stats.
Identities = 85/515 (17%), Positives = 189/515 (37%), Gaps = 53/515 (10%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIP----KEQYTIINRTA 86
+SP++P + C + KC + ++ + W + ++ II+
Sbjct 519 VSPKNPRIPKLHMLELHC--ESKCDSHLK-HSLKLSWSKDGEAFEINGTEDGRIIID--G 573
Query 87 SSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCE 145
+++T +++ C+ T ++ +T++ P+ P+NL + + +R
Sbjct 574 ANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVL--DVPDPPENLHLSERQNRSVRLT 631
Query 146 WDGGRETHLE-TNFTLKSEWATHKFA-DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENA 203
W+ G + + + + ++ E + + R TV FV + V A N
Sbjct 632 WEAGADHNSNISEYIVEFEGNKEEPGRWEELTRVQGKKTTVILPLAPFVRYQFRVIAVNE 691
Query 204 LGKV-TSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
+G+ S + P+ P N+ V S+ I+K ++ L+Y + +
Sbjct 692 VGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYRVTW 751
Query 262 RTKDAS-TWSQIPPEDTASTRSSFTVQDLKP--FTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+ + A W + T ++ T++ + P + Y +++ + + G G + +
Sbjct 752 KPQGAPVEWEE-------ETVTNHTLRVMTPAVYAPYDVKVQAINQLGSGPDP---QSVT 801
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
+ ED P AP I V++ W T+P +G++ Y++ + KS L
Sbjct 802 LYSGEDYPDTAP----VIHGVDVINSTLVKVTWSTVPKDRVHGRLKGYQINWWKTKSLLD 857
Query 379 NYTVNATKLTVNLTNDR-------------YLATLTVRNLVGKSDAAVLTIPACDFQATH 425
T + + R + T+ N G + I
Sbjct 858 GRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEPYIFQTPEGVPE 917
Query 426 PVMDLKAFPKD-NMLWVEWTTPRE---SVKKYILEWCVLSDKAP--CITDWQQEDGTVHR 479
LK D + + W P++ ++ Y+L++ +++D + D +
Sbjct 918 QPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPSKPS 977
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+L NL + Y + + G G P + ++
Sbjct 978 WHL-SNLNATTKYKFYLRACTSQGCGKPITEESST 1011
>sp|Q9VS29|DSCL_DROME Cell adhesion molecule Dscam2 OS=Drosophila
melanogaster OX=7227 GN=Dscam2 PE=2 SV=3
Length=2074
Score = 203 bits (516), Expect = 3e-52, Method: Composition-based stats.
Identities = 96/480 (20%), Positives = 149/480 (31%), Gaps = 46/480 (10%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A N G D + P PP L S + + W ++ + + KY
Sbjct 885 RASNLYGN---DQQLVQLQVQEPPLPPSVLEAAMI--SSRSVNIKWQPKTLGTGDVTKYI 939
Query 259 IQYRTKD---ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+++R D W QI +D + +++LKP T Y FR+ G+ S S+
Sbjct 940 VEFREADPLFVDQWQQIEVKD--PPHFNAMIENLKPATRYAFRVIAEGSAGR---SAPSQ 994
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
E T RP+ P S T + + W P +G I Y V S
Sbjct 995 ELIVRTEPQRPAGPPLSLSARPLSST----ELLISWVAPLPELRHGDIQGYNVGYKLSSS 1050
Query 376 HLQNYTVNATK-----------LTVNLTNDRYLATLTVRNLVGKSD--AAVLTIPACDFQ 422
Y + L+ RY + N VG D
Sbjct 1051 GNTAYNFTSVSGDGDGGNGELLLSGLAKFARYTVVVQAFNQVGPGPLSEPTAAQTMEDVP 1110
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPR-----ESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
+ P A L V W P ++ Y L + + D D + T
Sbjct 1111 SRPPEDVRCAALSSQSLQVSWQPPPIYHTNGLLQGYKLIFEPIIDDIQPSKDEVESRKTT 1170
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAV 536
T + L + Y I V G G + + + ++ P ++
Sbjct 1171 ALTMVLTGLRKYTNYSIQVLAHTRMGDGVVSKPLFCHSEEDVPEAPADIKVVSSSSQSLY 1230
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+ W LP + NG I Y+++ R + G E ++ S Y L Y +
Sbjct 1231 ISW--LPPNEPNGVITKYSLYTRVVNGREELNNEKRSLPSQQAYYEAKGLHPHMEYQFWV 1288
Query 593 AAYTDEGGKDGPE--FTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVL-FCFNKRDLIKK 649
A T G TT + I + PV + T L KR+ K
Sbjct 1289 TASTRVGEGKSSRVSSQITTNRI-PARIISFGGPVVRPWRSTVTLPCTAVGKPKREWFKS 1347
Score = 155 bits (391), Expect = 4e-37, Method: Composition-based stats.
Identities = 115/659 (17%), Positives = 208/659 (32%), Gaps = 92/659 (14%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEW--------ATHKFADCKA 174
+P P+++ C + ++ W TN L+ D
Sbjct 1108 DVPSRPPEDVRCAALSSQSLQVSWQPPPI--YHTNGLLQGYKLIFEPIIDDIQPSKDEVE 1165
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
R T V + N + V A +G F + P P ++ V++S
Sbjct 1166 SRKTTALTMVLTGLRKYTNYSIQVLAHTRMGDGVVSKPLFCHSEEDVPEAPADIKVVSSS 1225
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
S L ++W P+ + +I KY++ R + S ++ + + L P E
Sbjct 1226 SQS--LYISWLPPNEPNGVITKYSLYTRVVNGREELNNEKRSLPSQQAYYEAKGLHPHME 1283
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y F + G+G S S + IT P++ SF P TV L
Sbjct 1284 YQFWVTASTRVGEGKSSRVSSQ---ITTNRIPARIISF---GGPVVRPWRSTVTL----- 1332
Query 355 PPFEANGKI----LDYEVTLTRWKSHLQNYTVNATKLTVNL-TNDRYLATLTVRNLVGKS 409
P A GK +V L + H + + +L D + V N +G
Sbjct 1333 -PCTAVGKPKREWFKSDVALRQGGLHNSQLLDSGDLIISSLQLADGGNYSCQVDNGIGTD 1391
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKY-----ILEWCVLSDKA 464
I T PV+ + + + + + W + I + + +A
Sbjct 1392 RLTHTLI--VQVPPTAPVLYVTS-ATSSSILMHWK------CGFTGNAPITGYTLFYRRA 1442
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI-KAYLKQAPPSKGP 523
TD Q L+G L Y I ++ G +I + P
Sbjct 1443 NGNTDEMQLSRHASSHELKG-LMCGSTYQIHLSAQNKVGTSPTSTILHVRTQGQSPGHPA 1501
Query 524 TVRTKKVGKNEAVL---EWDQLPVDVQNGFIRNYTIF-YRTIIGNETAVNVDSS-----H 574
+ ++ W NG Y + YR + + A V S
Sbjct 1502 STALLAPNSTSLLVRLHSWPD------NGCPLLYFVLQYRAVTDDPDAEWVLVSNALKPQ 1555
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEG--------------GKDGPEFTFTTPKFAQGEIEA 620
+++L TLY +RM A+ G G P + Q +
Sbjct 1556 RRIVINNLQPSTLYQLRMEAHNVAGISQAEFNFVTLTKDGDPPPPEIMHRGRSGQTTVIF 1615
Query 621 ----IVVPV--CLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRH 674
+++P ++ + T++ ++ C+ H+ N P ++ Q
Sbjct 1616 ANINLLIPTIAAVSGMFCTIIMIIVCYR-------HMLKNAPPLAEQSQIQK----ESLE 1664
Query 675 NFNSKDQMYSDGNFTDVSVVEIEANDKKP-FPEDLKSLDLFKKEKINTEGHSSGIGGSS 732
N + + + + + V ++ NDK P ED+ F+ + GG +
Sbjct 1665 NRANSEAAQRERYYATIHKVSMQNNDKIPETSEDISPYATFQLSEAGGNMSQPHHGGPA 1723
Score = 155 bits (390), Expect = 6e-37, Method: Composition-based stats.
Identities = 85/533 (16%), Positives = 168/533 (32%), Gaps = 48/533 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEW-------DGGRETHLETNFTLKSEWAT-HKFADCKAKR 176
P P +LS ++ W G + L S T + F
Sbjct 1005 PAGPPLSLSARPLSSTELLISWVAPLPELRHGDIQGYNVGYKLSSSGNTAYNFTSVSGDG 1064
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEE 235
D + F V V+A N +G S+ + V PP ++ +
Sbjct 1065 DGGNGELLLSGLAKFARYTVVVQAFNQVGPGPLSEPTAAQTMEDVPSRPPEDVR--CAAL 1122
Query 236 LSSILKLTWTNPS--IKSVIILKYNIQYRT-KDASTWSQIPPEDTASTRSSFTVQDLKPF 292
S L+++W P + ++ Y + + D S+ E +T + + L+ +
Sbjct 1123 SSQSLQVSWQPPPIYHTNGLLQGYKLIFEPIIDDIQPSKDEVESRKTTALTMVLTGLRKY 1182
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
T Y ++ G G S+ + ED P + +++ + W
Sbjct 1183 TNYSIQVLAHTRMGDGV---VSKPLFCHSEEDVPEAPADIKVV-----SSSSQSLYISW- 1233
Query 353 TLPPFEANGKILDYEVTLT------RWKSHLQNYTVNATKLTVNLTND--RYLATLTVRN 404
LPP E NG I Y + + ++ + Y +T
Sbjct 1234 -LPPNEPNGVITKYSLYTRVVNGREELNNEKRSLPSQQAYYEAKGLHPHMEYQFWVTAST 1292
Query 405 LVGKSDAAVLTIPACDFQATHPVMDL---KAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
VG+ ++ ++ + ++ P + + + T + +++ L
Sbjct 1293 RVGEGKSSRVSSQITTNRIPARIISFGGPVVRPWRSTVTLPCTAVGKPKREWFKSDVALR 1352
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
+ + + LA+ Y V +G G+ + Q PP+
Sbjct 1353 QGGLHNSQLLDSGDLIISSLQ---LADGGNYSCQV----DNGIGTDRLTHTLIVQVPPTA 1405
Query 522 GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS 581
P + + ++ W N I YT+FYR GN + + + + L
Sbjct 1406 -PVLYVTSATSSSILMHWKCG--FTGNAPITGYTLFYRRANGNTDEMQLSRHASSHELKG 1462
Query 582 LTSDTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIE--AIVVPVCLAFLL 631
L + Y + ++A G T + G A++ P + L+
Sbjct 1463 LMCGSTYQIHLSAQNKVGTSPTSTILHVRTQGQSPGHPASTALLAPNSTSLLV 1515
Score = 139 bits (349), Expect = 5e-32, Method: Composition-based stats.
Identities = 97/625 (16%), Positives = 202/625 (32%), Gaps = 83/625 (13%)
Query 54 CMDYFHVNANYIVWKTNHFTIPK---EQYTIINRTASSVTFTDIASLNI-QLTCNILTFG 109
C ++W + +P T++++ +S ++ +++ + + TC
Sbjct 633 CGVSRGDPPLKLIWLKDGDPLPDLLGANVTMLDQYSSLLSIPSLSATHSGEYTCVAKNPA 692
Query 110 QLEQNVYGITIISGLPPE---KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWAT 166
+ Y + +PP +P + + N + C+ + T + +
Sbjct 693 --AEIKYTALLQVKVPPRWIVEPVDANVERNRHIMLHCQ-----AQGVPTPSIVWKKATG 745
Query 167 HKFADCKAKRDTPTSCTVDYSTVYFVNIE-----VWV-EAENALGKVTSDHINFDPVYKV 220
K + + R+ P + + ++ +++ ++ +A N +G I KV
Sbjct 746 SKSGEYEEVRERPFTKLLGNGSLLLQHVKEDREGFYLCQANNGIG----TGIGKVIQLKV 801
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
+P S + + +L+ + W + ++T +
Sbjct 802 NSSP-------YFSSTSRSVMVK-----KGDTALLQCAVSGDKPINIVWMR-SGKNTLNP 848
Query 281 RSSFTV---QDLKP-FTEYVFRIRCMKEDGKG-YWSDWSE-----EASGITYEDRPSKAP 330
+++ + Q+ P +IR + G Y+ S + P P
Sbjct 849 STNYKISVKQEATPDGVSAELQIRTVDATDSGPYFCRASNLYGNDQQLVQLQVQEPPLPP 908
Query 331 SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR--------WKSHLQNYTV 382
S + R+V + W+ P G + Y V W+
Sbjct 909 SVLE----AAMISSRSVNIKWQ--PKTLGTGDVTKYIVEFREADPLFVDQWQQIEVKDPP 962
Query 383 NATKLTVNL-TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATH-PVMDLKAFP-KDNML 439
+ + NL RY + G+S + I + Q P + L A P L
Sbjct 963 HFNAMIENLKPATRYAFRVIAEGSAGRSAPSQELIVRTEPQRPAGPPLSLSARPLSSTEL 1022
Query 440 WVEWTTP-----RESVKKYILEWCVLSDKAP--CITDWQQEDGTVHRTYLRGNLAESKCY 492
+ W P ++ Y + + + S T + + L LA+ Y
Sbjct 1023 LISWVAPLPELRHGDIQGYNVGYKLSSSGNTAYNFTSVSGDGDGGNGELLLSGLAKFARY 1082
Query 493 LITVTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGF 550
+ V GPG E A + PS+ P VR + + W P+ NG
Sbjct 1083 TVVVQAFNQVGPGPLSEPTAAQTMEDVPSRPPEDVRCAALSSQSLQVSWQPPPIYHTNGL 1142
Query 551 IRNYTIFYRTII-----GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
++ Y + + II + + ++ L+ L T Y +++ A+T G
Sbjct 1143 LQGYKLIFEPIIDDIQPSKDEVESRKTTALTMVLTGLRKYTNYSIQVLAHTRMGDG---- 1198
Query 606 FTFTTPKFAQGEIEAIVVPVCLAFL 630
+ P F E + P + +
Sbjct 1199 -VVSKPLFCHSEEDVPEAPADIKVV 1222
>sp|Q63155|DCC_RAT Netrin receptor DCC OS=Rattus norvegicus OX=10116
GN=Dcc PE=1 SV=2
Length=1445
Score = 202 bits (513), Expect = 6e-52, Method: Composition-based stats.
Identities = 82/439 (19%), Positives = 147/439 (33%), Gaps = 39/439 (9%)
Query 200 AENALGKVTSDHINFDP-----VYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
AEN G S P + P+ P + V+ S ++L+W P+ I
Sbjct 402 AENEAGNAQSSAQLIVPKPAIPSSSILPSAPRD--VVPVLVSSRFVRLSWRPPAEAKGNI 459
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
+ + + + + + T TV +LKP Y FR+ E G G + S
Sbjct 460 QTFTVFFSREGDNRERALNT--TQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPG---ESS 514
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK 374
+ T + P + + + ++ + W+ PP ANG + Y + T
Sbjct 515 QPIKVATQPELQVPGP---VENLHAVSASPTSILITWE--PPAYANGPVQGYRLFCTEVS 569
Query 375 SH-LQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAA--VLTIPACDFQATHPVMD 429
+ QN V+ + Y N G + + + D + P
Sbjct 570 TGKEQNIEVDGLSYKLEGLKKFTEYTLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNV 629
Query 430 LKAFPKDNMLWVEWTTPR-ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
+ V W P + +I + + K + + + YL L +
Sbjct 630 SLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLW-YLFTGLEK 688
Query 489 SKCYLITVTPVYADGPGSPESIKAYLKQAP---------PSKGPTVRTKKVGKNEAVLEW 539
Y V+ + +G G P + Y + P P + ++ + N ++ W
Sbjct 689 GSQYSFQVSAMTVNGTGPPSNW--YTAETPENDLDESQVPDQPSSLHVRPQT-NCIIMSW 745
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
P N +R Y I Y V VDS Y++ L S + Y++ + A+ + G
Sbjct 746 --TPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAG 803
Query 600 -GKDGPEFTFTTPKFAQGE 617
G E T +
Sbjct 804 EGVPLYESATTRSITDPTD 822
Score = 179 bits (454), Expect = 8e-45, Method: Composition-based stats.
Identities = 101/604 (17%), Positives = 194/604 (32%), Gaps = 80/604 (13%)
Query 42 SNFTAVCVLKEKCMDYFHVNANYIVWKTN-HFTIPKEQYTIINRTASSVTFTDIASLNIQ 100
+ C + K VN W N IP + + I+ + + + S
Sbjct 346 MDIEFECAVSGK--PVPTVN-----WMKNGDVVIPSDYFQIVGGSNLRILGV-VKSDEGF 397
Query 101 LTCNILTFGQLEQNVYGITI------ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRE--T 152
C Q+ + + S + P P+++ ++ + +R W E
Sbjct 398 YQCVAENEAGNAQSSAQLIVPKPAIPSSSILPSAPRDVVPVLVSSRFVRLSWRPPAEAKG 457
Query 153 HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-TSDH 211
+++T FT+ + + V A N G +S
Sbjct 458 NIQT-FTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQP 516
Query 212 INFDPVYKVK-PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS 270
I +++ P P NL +++ + + +TW P+ + + Y +
Sbjct 517 IKVATQPELQVPGPVENLHAVSA--SPTSILITWEPPAYANGPVQGYRLFCTEVSTGKEQ 574
Query 271 QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
I + S+ ++ LK FTEY R G G +D + + +T D PS P
Sbjct 575 NIEVDGL-----SYKLEGLKKFTEYTLRFLAYNRYGPGVSTD---DITVVTLSDVPSAPP 626
Query 331 SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN 390
R++++ W P NG I Y++ + + T+ L
Sbjct 627 QNVSL----EVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYL 682
Query 391 LT----NDRYLATLTVRNLVGKSDAA------VLTIPACDFQATHPVMDLKAFPKDNMLW 440
T +Y ++ + G + + Q L P+ N +
Sbjct 683 FTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTNCII 742
Query 441 VEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
+ WT P V+ YI+ + V S A + + R Y L S Y+I++
Sbjct 743 MSWTPPLNPNIVVRGYIIGYGVGSPYAETV-----RVDSKQRYYSIERLESSSHYVISLK 797
Query 498 PVYADGPGSP----ESIKAYLKQAPP---------------------SKGPTVRTKKVGK 532
G G P + ++ P V+ +
Sbjct 798 AFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSGPDVSTPMLPPVGVQAVALTH 857
Query 533 NEAVLEWDQ--LPVDVQNGFIRNYTIFYRTIIG-NETAVNVDSSHTEYTLSSLTSDTLYM 589
+ W +P + + +R YT+ +RT + + D++ YT + L +T+Y
Sbjct 858 EAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYE 917
Query 590 VRMA 593
+
Sbjct 918 FSVM 921
Score = 167 bits (423), Expect = 5e-41, Method: Composition-based stats.
Identities = 91/544 (17%), Positives = 166/544 (31%), Gaps = 62/544 (11%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSE 163
N G+ Q + T P +NL + + W+ +
Sbjct 506 NEWGPGESSQPIKVATQPELQVPGPVENLHAVSASPTSILITWEPPAYANGPVQG--YRL 563
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKP 222
+ T + + F + A N G V++D I + V
Sbjct 564 FCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYTLRFLAYNRYGPGVSTDDITVVTLSDVPS 623
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIK--SVIILKYNIQYRTKDASTWSQIPPEDTAST 280
PP N+S+ S +K++W P + I Y I++R E
Sbjct 624 APPQNVSLEVVN--SRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRG----EMETLEPN 677
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR--PSKAPSFWYKIDP 338
+ L+ ++Y F++ M +G G S+W + T E+ S+ P +
Sbjct 678 NLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNW---YTAETPENDLDESQVPDQPSSLHV 734
Query 339 SHTQGYRTVQLVWKTLPPFEAN----GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND 394
+ + W PP N G I+ Y V ++ + + ++
Sbjct 735 RPQTNC--IIMSW--TPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSS 790
Query 395 RYLATLTVRNLVGKS-----DAAVLTI--------------------PACDFQATHPVMD 429
Y+ +L N G+ A +I P PV
Sbjct 791 HYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSGPDVSTPMLPPVGV 850
Query 430 LKAFPKDNMLWVEW---TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
+ V W + P+ + + V + + + + T +Y L
Sbjct 851 QAVALTHEAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGL 910
Query 487 AESKCYLITVTPV-YADGPGSPESIKAYLKQAPPSKGP---TVRTKKVGKNEAVLEWDQL 542
+ Y +V + A +A P+ P TV T++ ++ W
Sbjct 911 KPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPRAVIVSWQ-- 968
Query 543 PVDVQNGFIRNYTIFYR----TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
P NG I Y +FY I + + + + L+ DT+Y R+ A +
Sbjct 969 PPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLSLDTMYYFRIQARNAK 1028
Query 599 GGKD 602
G
Sbjct 1029 GVGP 1032
Score = 138 bits (346), Expect = 1e-31, Method: Composition-based stats.
Identities = 73/331 (22%), Positives = 112/331 (34%), Gaps = 26/331 (8%)
Query 314 SEEASGITYEDRPSKA--PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
S + PS + PS + P R V+L W+ PP EA G I + V +
Sbjct 411 SSAQLIVPKPAIPSSSILPSAPRDVVPVLVSS-RFVRLSWR--PPAEAKGNIQTFTVFFS 467
Query 372 RWKSHLQNYTVNATKLTVNLT------NDRYLATLTVRN--LVGKSDAAVLTIPACDFQA 423
R + + ++ LT Y + N G+S + + Q
Sbjct 468 REGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQV 527
Query 424 THPVMDLKAFPKD-NMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
PV +L A + + W P V+ Y L +S Q +
Sbjct 528 PGPVENLHAVSASPTSILITWEPPAYANGPVQGYRLFCTEVSTGKE-----QNIEVDGLS 582
Query 480 TYLRGNLAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVL 537
L G L + Y + GPG S + I PS P V + V +
Sbjct 583 YKLEG-LKKFTEYTLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKV 641
Query 538 EWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
W P QNGFI Y I +R ++ ++ Y + L + Y +++A T
Sbjct 642 SWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTV 701
Query 598 EG-GKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
G G +T TP+ E + P L
Sbjct 702 NGTGPPSNWYTAETPENDLDESQVPDQPSSL 732
Score = 122 bits (305), Expect = 7e-27, Method: Composition-based stats.
Identities = 78/446 (17%), Positives = 152/446 (34%), Gaps = 54/446 (12%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG---GRETHLETNFTL 160
N G ++ +T+ S +P P+N+S V + ++ W G + T + +
Sbjct 602 NRYGPGVSTDDITVVTL-SDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKI 660
Query 161 KSEWATHKFADCKAKRDTPTSC-TVDYSTVYFVNIEVWVEAENALGKVTSDHINF----- 214
+ T + + + P + + V A G +
Sbjct 661 RHRKTTRRG---EMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPE 717
Query 215 -DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
D P+ P +L V ++ + ++WT P ++++ Y I Y + +
Sbjct 718 NDLDESQVPDQPSSLHVRPQ---TNCIIMSWTPPLNPNIVVRGYIIGY-GVGSPYAETVR 773
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT-----------Y 322
S + ++++ L+ + YV ++ G+G S IT
Sbjct 774 ---VDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLL 830
Query 323 EDRPSKAPSFWYKIDP-----SHTQGYRTVQLVW--KTLPPFEANGKILDYEVTLTRWKS 375
+D P+ P + P + + V++ W ++P + + Y V S
Sbjct 831 DDFPTSGPDVSTPMLPPVGVQAVALTHEAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFS 890
Query 376 HLQNY-TVNATKLTVNLT----NDRYLATLTVRNLVGKSDAAVLTIPAC-DFQATHPVMD 429
Y + + T L+ T N Y ++ V S ++ + T D
Sbjct 891 ASAKYKSEDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKD 950
Query 430 LKAFPKDN---MLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHR-TYL 482
L ++ + V W P E+ + YIL + + DK I DW E + R T+
Sbjct 951 LTVITREGKPRAVIVSWQPPLEANGKITAYILFYTL--DKNIPIDDWIMETISGDRLTHQ 1008
Query 483 RGNLAESKCYLITVTPVYADGPGSPE 508
+L+ Y + A G G
Sbjct 1009 IMDLSLDTMYYFRIQARNAKGVGPLS 1034
Score = 82.2 bits (201), Expect = 2e-14, Method: Composition-based stats.
Identities = 41/199 (21%), Positives = 68/199 (34%), Gaps = 9/199 (5%)
Query 122 SGLPPEKPKNLSCIVNEGKKMRCEW-DGGRETHLETN----FTLKSEWATHKFADCKAKR 176
P P + + + +R W D + +T+ +T++ W T A K K
Sbjct 840 VSTPMLPPVGVQAVALTHEAVRVSWADNSVPKNQKTSDVRLYTVR--WRTSFSASAKYKS 897
Query 177 DTPTSCTVDYSTVY-FVNIEVWVEAE-NALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
+ TS + + + E V N S + + P +L+VI E
Sbjct 898 EDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITRE 957
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ ++W P + I Y + Y E + R + + DL T
Sbjct 958 GKPRAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLSLDTM 1017
Query 295 YVFRIRCMKEDGKGYWSDW 313
Y FRI+ G G SD
Sbjct 1018 YYFRIQARNAKGVGPLSDP 1036
>sp|Q28172|PRLR_BOVIN Prolactin receptor OS=Bos taurus OX=9913
GN=PRLR PE=1 SV=1
Length=581
Score = 194 bits (492), Expect = 2e-51, Method: Composition-based stats.
Identities = 62/221 (28%), Positives = 98/221 (44%), Gaps = 15/221 (7%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHK-FADCK-AKRDTPTSC 182
PPEKPK + C + C W+ G + L TN+TL +C K P SC
Sbjct 27 PPEKPKLVKCRSPGKETFTCWWEPGADGGLPTNYTLTYHKEGETLIHECPDYKTGGPNSC 86
Query 183 TVDYSTVYFVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV--INSEELSSI 239
+ V A N +G +SD + Y V+P PP NL++ + E+
Sbjct 87 YFSKKHTSIWKMYVITVNAINQMGISSSDPLYVHVTYIVEPEPPANLTLELKHPEDRKPY 146
Query 240 LKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
L + W+ P++ V I++Y I+ + + A+ W ++ + +L P +Y
Sbjct 147 LWIKWSPPTMTDVKSGWFIIQYEIRLKPEKATDWET----HFTLKQTQLKIFNLYPGQKY 202
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ +IRC + GYWS+WS E+S D P K S W +
Sbjct 203 LVQIRCKPD--HGYWSEWSPESSIQIPNDFPVKDTSMWIFV 241
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 48/283 (17%), Positives = 87/283 (31%), Gaps = 25/283 (9%)
Query 490 KCYLITVTPVYADGPGSPESIKA---YLKQAPPSKGPTVRTKKVGKNE--AVLEWDQLPV 544
K Y+ITV + G S + + Y+ + P T+ K + ++W +
Sbjct 97 KMYVITVNAINQMGISSSDPLYVHVTYIVEPEPPANLTLELKHPEDRKPYLWIKWSPPTM 156
Query 545 DVQNG--FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
FI Y I + + + T+ + +L Y+V++ D G
Sbjct 157 TDVKSGWFIIQYEIRLKPEKATDWETHFTLKQTQLKIFNLYPGQKYLVQIRCKPDHGYWS 216
Query 603 --GPEFTFTT----PKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVP 656
PE + P + + + L+ L ++ I P VP
Sbjct 217 EWSPESSIQIPNDFPVKDTSMWIFVAILSAVICLIMVWAVALKGYSMVTCIL----PPVP 272
Query 657 DPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKK 716
P I + H + + +F S E + + + +
Sbjct 273 GP---KIKGFDVHLLEKGKSEELLRALESQDFPPTSDCEDLLMEFIEVDDCEDQQLMPRP 329
Query 717 EKINTE-----GHSSGIGGSSCMSSSRPSISSSDENESSQNTS 754
K +TE H S S PS+ S +E + S
Sbjct 330 SKEHTEQGVKPMHLDLDSDSGRGSCDSPSLLSEKCDEPQAHPS 372
Score = 49.5 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 32/191 (17%), Positives = 56/191 (29%), Gaps = 15/191 (8%)
Query 330 PSFWYKIDPSHTQGYRTVQLVWKT-LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLT 388
P K+ + G T W+ L Y +Y
Sbjct 27 PPEKPKLVKCRSPGKETFTCWWEPGADGGLPTNYTLTYHKEGETLIHECPDYKTGGPNSC 86
Query 389 VNLTN-----DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF-----PKDNM 438
Y+ T+ N +G S + L + P +L +
Sbjct 87 YFSKKHTSIWKMYVITVNAINQMGISSSDPLYVHVTYIVEPEPPANLTLELKHPEDRKPY 146
Query 439 LWVEWTTPRESVKK---YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLIT 495
LW++W+ P + K +I+++ + K TDW+ NL + YL+
Sbjct 147 LWIKWSPPTMTDVKSGWFIIQYEIRL-KPEKATDWETHFTLKQTQLKIFNLYPGQKYLVQ 205
Query 496 VTPVYADGPGS 506
+ G S
Sbjct 206 IRCKPDHGYWS 216
>sp|P13944|COCA1_CHICK Collagen alpha-1(XII) chain OS=Gallus gallus
OX=9031 GN=COL12A1 PE=1 SV=3
Length=3124
Score = 201 bits (510), Expect = 2e-51, Method: Composition-based stats.
Identities = 108/534 (20%), Positives = 172/534 (32%), Gaps = 51/534 (10%)
Query 82 INRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKK 141
I+R +S T TD++S + + + + E + S +P P NL
Sbjct 1614 IDRLKTSTTLTDLSSQRLYNVKVVAVYDEGESLPVVASCYSAVP--SPVNLRITEITKNS 1671
Query 142 MRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAE 201
R WD G T + + A+ D + + + EV V A
Sbjct 1672 FRGTWDHGAPDVSLYRIT-WGPYGRSEKAESIVNGDVNSLLFENLNPD--TLYEVSVTAI 1728
Query 202 NALGKVTSDHI-----NFDPVYKVKPNP---PHNLSVINSEELSSILKLTWTNPSIKSVI 253
T D + V P P P NL V S L + W S
Sbjct 1729 YPDESETVDDLIGSERTLPLVPITTPAPKSGPRNLQV--YNATSHSLTVKWDP---ASGR 1783
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ +Y I Y+ + Q ++S +Q L+P T Y + M DG+G
Sbjct 1784 VQRYKIIYQPINGDGPEQSTM--VGGRQNSVVIQKLQPDTPYAITVSSMYADGEGG---- 1837
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
+P DP+ + T+ + W A G Y+V
Sbjct 1838 ---RMTGRGRTKPLTTVKNMLVYDPTTS----TLNVRWD-----HAEGNPRQYKVFYRPT 1885
Query 374 KSHLQNYTV---NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
+ T N + + T+TV + + D T + P
Sbjct 1886 AGGAEEMTTVPGNTNYVILRSLEPNTPYTVTVVPVFPEGDGGRTTDTGRTLERGTPRNIQ 1945
Query 431 KAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
P N + V W V++Y + + LS P + R + L
Sbjct 1946 VYNPTPNSMNVRWEPAPGPVQQYRVNYSPLSGPRPSES---IVVPANTRDVMLERLTPDT 2002
Query 491 CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
Y I V +YADG G+P + P S +R N ++WD +G
Sbjct 2003 AYSINVIALYADGEGNPSQAQGRT--LPRSGPRNLRVFDETTNSLSVQWDH-----ADGP 2055
Query 551 IRNYTIFYRTIIGN--ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
++ Y I Y +G+ + V L L SDT Y + + A ++G
Sbjct 2056 VQQYRIIYSPTVGDPIDEYTTVPGIRNNVILQPLQSDTPYKITVVAVYEDGDGG 2109
Score = 161 bits (407), Expect = 6e-39, Method: Composition-based stats.
Identities = 103/606 (17%), Positives = 191/606 (32%), Gaps = 47/606 (8%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTD 93
P + S T + + Y V P +Q+ + +R ++ D
Sbjct 1386 PPPSNLVISEVTPH-SFRLRWSPPPESVDRYRVEYYPTTGGPPKQFYV-SRMETTTVLKD 1443
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH 153
+ + N+ + + E + I P +NL+ MR W+ +
Sbjct 1444 LT-PETEYIVNVFSVVEDESSEPLIGREITYPLSSVRNLNVYDIGSTSMRVRWEPV---N 1499
Query 154 LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN 213
T + L E + + S N E + A G +TSD +
Sbjct 1500 GATGYLLTYEPVNATVPTTEKEMRVGPSVNEVQLVDLIPNTEYTLTAYVLYGDITSDPLT 1559
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
V P P V + S + + W + KY I+Y+ D + ++
Sbjct 1560 SQEVTLPLPGP---RGVTIRDVTHSTMNVLWDP---APGKVRKYIIRYKIADEADVKEVE 1613
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
+ ++S T+ DL Y ++ + ++G+ S Y PS P
Sbjct 1614 IDRL---KTSTTLTDLSSQRLYNVKVVAVYDEGE------SLPVVASCYSAVPS--PVNL 1662
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN 393
+ + T W P + +I + + N VN+ +
Sbjct 1663 RITEITKNSFRGT----WDHGAPDVSLYRITWGPYGRSEKAESIVNGDVNSLLFENLNPD 1718
Query 394 DRYLATLTV--------RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN-MLWVEWT 444
Y ++T + + S+ + +P +L+ + + L V+W
Sbjct 1719 TLYEVSVTAIYPDESETVDDLIGSERTLPLVPITTPAPKSGPRNLQVYNATSHSLTVKWD 1778
Query 445 TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
V++Y + + ++ P + G + + L Y ITV+ +YADG
Sbjct 1779 PASGRVQRYKIIYQPINGDGPEQSTMV---GGRQNSVVIQKLQPDTPYAITVSSMYADGE 1835
Query 505 GSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT-IIG 563
G + + K + + + + WD G R Y +FYR G
Sbjct 1836 GGRMTGRGRTKPL--TTVKNMLVYDPTTSTLNVRWDH-----AEGNPRQYKVFYRPTAGG 1888
Query 564 NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
E V + L SL +T Y V + EG T T + +
Sbjct 1889 AEEMTTVPGNTNYVILRSLEPNTPYTVTVVPVFPEGDGGRTTDTGRTLERGTPRNIQVYN 1948
Query 624 PVCLAF 629
P +
Sbjct 1949 PTPNSM 1954
Score = 158 bits (400), Expect = 4e-38, Method: Composition-based stats.
Identities = 93/606 (15%), Positives = 179/606 (30%), Gaps = 76/606 (13%)
Query 80 TIINRTASSVTFTDIAS---LNIQLTCNILTFGQLEQNVYGITIISGLPP-------EKP 129
+I+N +S+ F ++ + +T + ++ G L P P
Sbjct 1701 SIVNGDVNSLLFENLNPDTLYEVSVTAIYPDESETVDDLIGSERTLPLVPITTPAPKSGP 1760
Query 130 KNLSCIVNEGKKMRCEWDG--GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
+NL + +WD GR + + + + + V
Sbjct 1761 RNLQVYNATSHSLTVKWDPASGRV----QRYKIIYQPINGDGPEQSTMVGGRQNSVVIQK 1816
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS-VINSEELSSILKLTWTN 246
+ V + A G+ + + P + ++ + +S L + W +
Sbjct 1817 LQPDTPYAITVSSMYADGEGG------RMTGRGRTKPLTTVKNMLVYDPTTSTLNVRWDH 1870
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+Y + YR + ++ L+P T Y + + +G
Sbjct 1871 AE---GNPRQYKVFYRPTAGGAEEMTT---VPGNTNYVILRSLEPNTPYTVTVVPVFPEG 1924
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
G + T P +P+ ++ + W+ P G + Y
Sbjct 1925 DGG-------RTTDTGRTLERGTPRNIQVYNPT----PNSMNVRWEPAP-----GPVQQY 1968
Query 367 EVTLTRWKSHLQNYTVNATKLTVNL------TNDRYLATLTVRNLVGKSDAAVLTIPACD 420
V + + ++ T ++ + Y + G+ + +
Sbjct 1969 RVNYSPLSGPRPSESIVVPANTRDVMLERLTPDTAYSINVIALYADGEGNPS--QAQGRT 2026
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ P N L V+W V++Y + + I ++ G +
Sbjct 2027 LPRSGPRNLRVFDETTNSLSVQWDHADGPVQQYRIIYSPTVGD--PIDEYTTVPGIRNNV 2084
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
L+ L Y ITV VY DG G + P + + WD
Sbjct 2085 ILQ-PLQSDTPYKITVVAVYEDGDGGQLTGNGRTVGLLP--PQNIYITDEWYTRFRVSWD 2141
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
P + Y I Y+ + NE T YTL +L+ T Y V + A D G
Sbjct 2142 PSP-----SPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLSPSTTYDVNVYAQYDSG- 2195
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGV-LFCFNKRDLIKKHIWPNVPDPS 659
+ P QG + + + L T +G FC + +P+
Sbjct 2196 -------MSIPLTDQGT----TLYLNVTDLTTYKIGWDTFCIRWSPHRSATSYRLKLNPA 2244
Query 660 KSHIAQ 665
Q
Sbjct 2245 DGSRGQ 2250
Score = 153 bits (386), Expect = 2e-36, Method: Composition-based stats.
Identities = 83/567 (15%), Positives = 170/567 (30%), Gaps = 55/567 (10%)
Query 74 IPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYG-------ITIISGLPP 126
T+ + + + + +YG + LP
Sbjct 1508 YEPVNATVPTTEKEMRVGPSVNEVQLVDLIPNTEYTLTAYVLYGDITSDPLTSQEVTLPL 1567
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
P+ ++ M WD + ++ + A + + D + T
Sbjct 1568 PGPRGVTIRDVTHSTMNVLWDPA--PGKVRKYIIRYKIADEADVK-EVEIDRLKTSTTLT 1624
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V V A G S + V P NL + +E + + TW +
Sbjct 1625 DLSSQRLYNVKVVAVYDEG--ESLPVVASCYSAVPS--PVNLRI--TEITKNSFRGTWDH 1678
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ + Y I + S ++ +S ++L P T Y + + D
Sbjct 1679 GAP---DVSLYRITWGPYGRSEKAE---SIVNGDVNSLLFENLNPDTLYEVSVTAIYPDE 1732
Query 307 KGY-----WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
S+ + IT P P + + ++ + W A+G
Sbjct 1733 SETVDDLIGSERTLPLVPITTPA-PKSGPRNLQVYNATS----HSLTVKWDP-----ASG 1782
Query 362 KILDYEVTLTR----WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
++ Y++ + + +TV ++ + +T
Sbjct 1783 RVQRYKIIYQPINGDGPEQSTMVGGRQNSVVIQKLQPDTPYAITVSSMYADGEGGRMTGR 1842
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
T L P + L V W + ++Y + + + A +T G
Sbjct 1843 GRTKPLTTVKNMLVYDPTTSTLNVRWDHAEGNPRQYKVFYRPTAGGAEEMT---TVPGNT 1899
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVL 537
+ LR L + Y +TV PV+ +G G + + ++ N +
Sbjct 1900 NYVILRS-LEPNTPYTVTVVPVFPEGDGGRTTDTGRTLER--GTPRNIQVYNPTPNSMNV 1956
Query 538 EWDQLPVDVQNGFIRNYTIFYRTIIGN--ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
W+ P G ++ Y + Y + G ++ V ++ + L LT DT Y + + A
Sbjct 1957 RWEPAP-----GPVQQYRVNYSPLSGPRPSESIVVPANTRDVMLERLTPDTAYSINVIAL 2011
Query 596 TDEGGKDGPEFTFTT-PKFAQGEIEAI 621
+G + + T P+ +
Sbjct 2012 YADGEGNPSQAQGRTLPRSGPRNLRVF 2038
Score = 148 bits (374), Expect = 6e-35, Method: Composition-based stats.
Identities = 89/532 (17%), Positives = 166/532 (31%), Gaps = 68/532 (13%)
Query 93 DIASLNIQLTCNILTFGQL-EQNVYGITIISG-LPPEKPKNLSCIVNEGKKMRCEWDGGR 150
DI + N+ + + G+ N+ G LPP P NL R W
Sbjct 1352 DIHAYNVADFSFLASIGEDVTTNLCNSVKGPGDLPP--PSNLVISEVTPHSFRLRWSPPP 1409
Query 151 ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF-----VNIEVWVEAENALG 205
E+ + + ++ +TV V V + +
Sbjct 1410 ESV--------DRYRVEYYPTTGGPPKQFYVSRMETTTVLKDLTPETEYIVNVFSV--VE 1459
Query 206 KVTSDHINFDPVYKVKPNPP-HNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK 264
+S+ + P NL+V + S+ +++ W + + +L Y
Sbjct 1460 DESSEPLIGR--EITYPLSSVRNLNVYDIG--STSMRVRWEPVNGATGYLLTYE----PV 1511
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW--SEEASGITY 322
+A+ + + + + DL P TEY + G SD S+E +
Sbjct 1512 NATVPTTEKEMRVGPSVNEVQLVDLIPNTEYT--LTAYVLYGDIT-SDPLTSQEVTL--- 1565
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
P P D +H+ T+ ++W P I+ Y++ ++ +
Sbjct 1566 ---PLPGPRGVTIRDVTHS----TMNVLWDPAPGK-VRKYIIRYKIADEADVKEVEIDRL 1617
Query 383 NATKLTVNLTNDR-YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
+ +L++ R Y + G+S + +C PV N
Sbjct 1618 KTSTTLTDLSSQRLYNVKVVAVYDEGESLP---VVASCYSAVPSPVNLRITEITKNSFRG 1674
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
W V Y + W + + L NL Y ++VT +Y
Sbjct 1675 TWDHGAPDVSLYRITWGPYGRSEKA----ESIVNGDVNSLLFENLNPDTLYEVSVTAIYP 1730
Query 502 D---------GPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
D G + AP S ++ + ++WD +G ++
Sbjct 1731 DESETVDDLIGSERTLPLVPITTPAPKSGPRNLQVYNATSHSLTVKWDP-----ASGRVQ 1785
Query 553 NYTIFYRTI--IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
Y I Y+ I G E + V + L DT Y + +++ +G
Sbjct 1786 RYKIIYQPINGDGPEQSTMVGGRQNSVVIQKLQPDTPYAITVSSMYADGEGG 1837
Score = 145 bits (365), Expect = 7e-34, Method: Composition-based stats.
Identities = 96/550 (17%), Positives = 168/550 (31%), Gaps = 50/550 (9%)
Query 69 TNHFTIPKEQYTIINRTASSVTFTDIASLN-IQLTCNILTFGQLEQNVYGITIISGLPPE 127
+ E T D + I ++EQ + I P
Sbjct 576 KDAVRTELEAIASPPAETHVYTVEDFDAFQRISFELTQSVCLRIEQELAAIR-KKSYVPA 634
Query 128 KPKNLSCIVNEGKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
K N+ + W G E E ++ +K + A + ++ +V
Sbjct 635 K--NMVFSDVTSDSFKVSWSAAGSE---EKSYLIKYKVAIGG-DEFIVSVPASSTSSVLT 688
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ + V V AE G ++ + P NL + ++E + + WT
Sbjct 689 NLLPETTYAVSVIAEYEDGDGP--PLDGEETTLEVKGAPRNLRI--TDETTDSFIVGWTP 744
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+L+Y + YR Q+ ++ S T+++L P T Y + + G
Sbjct 745 ---APGNVLRYRLVYRPLTGGERRQVT---VSANERSTTLRNLIPDTRYEVSVIAEYQSG 798
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD- 365
G +G D P + S T++L W P GK+
Sbjct 799 PG------NALNGYAKTDEVRGNP---RNLRVSDATTSTTMKLSWSAAP-----GKVQHV 844
Query 366 -YEVTLTRWKSHLQNYTVNATKLTVNLTN----DRYLATLTVRNLVGKSDAAVLTIPACD 420
Y + + TV + L RY T++ G + A+
Sbjct 845 LYNLHTRYAGVETKELTVKGDTTSKELKGLDEATRYALTVSALYASGAGE-ALSGEGETL 903
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ P + D + + WT +V Y + W L D ++ G
Sbjct 904 EERGSPRNLITTDITDTTVGLSWTPAPGTVNNYRIVWKSLYDD---TMGEKRVPGNTVDA 960
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
L G L Y I++ Y+ G G P +A+ TV +N +
Sbjct 961 VLDG-LEPETKYRISIYAAYSSGEGDPVEGEAFTD--VSQSARTVTVDNETENTMRVS-- 1015
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
+ G + + G + V++S T L L T Y + + D G
Sbjct 1016 -VAALTWEGLVLA-RVLPNRSGGRQMFGKVNASATSIVLKRLKPRTTYDLSVVPIYDFGQ 1073
Query 601 KDGPEFTFTT 610
+ TT
Sbjct 1074 GKSRKAEGTT 1083
Score = 125 bits (313), Expect = 1e-27, Method: Composition-based stats.
Identities = 77/538 (14%), Positives = 141/538 (26%), Gaps = 51/538 (9%)
Query 76 KEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCI 135
EQ T++ +SV + + + + + P KN+
Sbjct 1799 PEQSTMVGGRQNSVVIQKLQ-PDTPYAITVSSMYADGEGGRMTGRGRTKPLTTVKNMLVY 1857
Query 136 VNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIE 195
+ WD + + + +
Sbjct 1858 DPTTSTLNVRWD--HAEGNPRQYKVFYRPTAGGAEEMTTVPGNTNYVILRSLEP-NTPYT 1914
Query 196 VWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
V V G + + P N+ V N + + + W +
Sbjct 1915 VTVVPVFPEGDGGRTTDTGRTLER---GTPRNIQVYNP--TPNSMNVRWEP---APGPVQ 1966
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+Y + Y S+ + ++ L P T Y + + DG+G S
Sbjct 1967 QYRVNYSPLSGPRPSESIV--VPANTRDVMLERLTPDTAYSINVIALYADGEGNPS---- 2020
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
+A G T P P D + ++ + W A+G + Y + +
Sbjct 2021 QAQGRTL---PRSGPRNLRVFDETTN----SLSVQWD-----HADGPVQQYRIIYSPTVG 2068
Query 376 ----HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
+ + +TV + D LT P
Sbjct 2069 DPIDEYTTVPGIRNNVILQPLQSDTPYKITVVAVYEDGDGGQLTGNGRTVGLLPPQNIYI 2128
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
V W V Y + + + P + G V L NL+ S
Sbjct 2129 TDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEP----MEVFVGEVTSYTLH-NLSPSTT 2183
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
Y + V Y G P + + + + T K+G + + W
Sbjct 2184 YDVNVYAQYDSGMSIPLTDQGTTLYLNVT---DLTTYKIGWDTFCIRWSPHRS------A 2234
Query 552 RNYTIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLY--MVRMAAYTDEGGKDGPEF 606
+Y + G+ + V S T + + L+ DT Y V + EG
Sbjct 2235 TSYRLKLNPADGSRGQEITVRGSETSHCFTGLSPDTEYNATVFVQTPNLEGPPVSVRE 2292
Score = 116 bits (291), Expect = 4e-25, Method: Composition-based stats.
Identities = 79/486 (16%), Positives = 148/486 (30%), Gaps = 51/486 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
P+NL W L + + + + T+
Sbjct 723 GAPRNLRITDETTDSFIVGWTPAPGNVLRYRLVYRPLTGGERRQVTVSANERSTTLR--- 779
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ + EV V AE G + + +V+ P NL V ++ S+ +KL+W+
Sbjct 780 NLIPDTRYEVSVIAEYQSGPGNALNGYAK-TDEVR-GNPRNLRVSDAT-TSTTMKLSWSA 836
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
K +L YN+ R T +S ++ L T Y + + G
Sbjct 837 APGKVQHVL-YNLHTRYAGVET----KELTVKGDTTSKELKGLDEATRYALTVSALYASG 891
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
G + G T E+R S + + TV L W P G + +Y
Sbjct 892 AGE----ALSGEGETLEERGSP------RNLITTDITDTTVGLSWTPAP-----GTVNNY 936
Query 367 EVTLTRWKS---HLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPACDF 421
+ + N ++ +Y ++ G+ D
Sbjct 937 RIVWKSLYDDTMGEKRVPGNTVDAVLDGLEPETKYRISIYAAYSSGEGDPVEGEAFTDVS 996
Query 422 QATHPVMDLKAFPKDNMLWV---EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
Q+ V + V W ++ VL +++ + + + +
Sbjct 997 QSARTVTVDNETENTMRVSVAALTWE--------GLVLARVLPNRSGGRQMFGKVNASAT 1048
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
L+ L Y ++V P+Y G G + +P +RT + +
Sbjct 1049 SIVLK-RLKPRTTYDLSVVPIYDFGQGKSRKAEGTTA-SPFKPPRNLRTSDSTMSSFRVT 1106
Query 539 WDQLPVDVQNGFIRNYTIFY--RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
W+ P G ++ Y + + N + V + L L + T Y V +
Sbjct 1107 WEPAP-----GRVKGYKVTFHPTEDDRNLGELVVGPYDSTVVLEELRAGTTYKVNVFGMF 1161
Query 597 DEGGKD 602
D G +
Sbjct 1162 DGGESN 1167
Score = 83.4 bits (204), Expect = 9e-15, Method: Composition-based stats.
Identities = 64/415 (15%), Positives = 121/415 (29%), Gaps = 48/415 (12%)
Query 129 PKNLSCI-VNEGKKMRCEWD--GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P+NL M+ W G+ H + L + +A + + K DT +
Sbjct 816 PRNLRVSDATTSTTMKLSWSAAPGKVQH--VLYNLHTRYAGVETKELTVKGDTTSKELKG 873
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ V A A G + ++ + + P NL I ++ + + L+WT
Sbjct 874 LDEA--TRYALTVSALYASGAGEA--LSGEGETLEERGSPRNL--ITTDITDTTVGLSWT 927
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
+ Y I +++ T + + + L+P T+Y I
Sbjct 928 P---APGTVNNYRIVWKSLYDDTMGE---KRVPGNTVDAVLDGLEPETKYRISIYAAYSS 981
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G+G + G + D A + + +T L W+ G +L
Sbjct 982 GEG------DPVEGEAFTDVSQSARTVTVDNETENTMRVSVAALTWE--------GLVLA 1027
Query 366 YEVT-LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
+ + + +AT + + R L+V +
Sbjct 1028 RVLPNRSGGRQMFGKVNASATSIVLKRLKPRTTYDLSVVPIYDFGQGKSRKAEGTTASPF 1087
Query 425 HPVMDL-KAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
P +L + + V W VK Y + + G T +
Sbjct 1088 KPPRNLRTSDSTMSSFRVTWEPAPGRVKGYKV---TFHPTEDDRNLGELVVGPYDSTVVL 1144
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
L Y + V ++ G ++ P G + T E L
Sbjct 1145 EELRAGTTYKVNVFGMFDGG------------ESNPLVGQEMTTLSDTTTEPFLS 1187
Score = 48.3 bits (113), Expect = 4e-04, Method: Composition-based stats.
Identities = 12/87 (14%), Positives = 27/87 (31%), Gaps = 7/87 (8%)
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT--IIGNETAV 568
+ + + ++ + WD I Y + + G + +
Sbjct 325 ELVSGEEVVEPASNLVATQISSKSVRITWDPS-----TSQITGYRVQFIPMIAGGKQHVL 379
Query 569 NVDSSHTEYTLSSLTSDTLYMVRMAAY 595
+V T + L+ DT Y + + A
Sbjct 380 SVGPQTTALNVKDLSPDTEYQINVYAM 406
Score = 44.8 bits (104), Expect = 0.005, Method: Composition-based stats.
Identities = 21/97 (22%), Positives = 33/97 (34%), Gaps = 13/97 (13%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P NL S +++TW + I Y +Q+ A + +
Sbjct 334 EPASNLVATQI--SSKSVRITWDP---STSQITGYRVQFIPMIAGGKQHV--LSVGPQTT 386
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ V+DL P TEY + MK SE +
Sbjct 387 ALNVKDLSPDTEYQINVYAMKGL------TPSEPITI 417
Score = 44.5 bits (103), Expect = 0.006, Method: Composition-based stats.
Identities = 34/242 (14%), Positives = 69/242 (29%), Gaps = 30/242 (12%)
Query 75 PKEQYTIINRTASSVTFTDIAS-LNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLS 133
P ++YT + ++V + S ++T + + G GL P P+N+
Sbjct 2070 PIDEYTTVPGIRNNVILQPLQSDTPYKITVVAVYEDGDGGQLTGNGRTVGLLP--PQNIY 2127
Query 134 CIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN 193
+ R WD L K + + + T ++
Sbjct 2128 ITDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYT----LHNLSPSTT 2183
Query 194 IEVWVEAENALGKV-----TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
+V V A+ G + + + + + W+
Sbjct 2184 YDVNVYAQYDSGMSIPLTDQGTTLYLNVTD-----------LTTYKIGWDTFCIRWSPHR 2232
Query 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
+ Y ++ D S +I + +S L P TEY + + +G
Sbjct 2233 SATS----YRLKLNPADGSRGQEITVR---GSETSHCFTGLSPDTEYNATVFVQTPNLEG 2285
Query 309 YW 310
Sbjct 2286 PP 2287
Score = 43.3 bits (100), Expect = 0.013, Method: Composition-based stats.
Identities = 18/82 (22%), Positives = 33/82 (40%), Gaps = 8/82 (10%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
NPP +L+ +E + ++++W P I+ Y I + + + + +
Sbjct 26 NPPSDLNFTIIDEHN--VQMSWKRPPD---AIVGYRITVVPTNDGPTKEFT---LSPSTT 77
Query 283 SFTVQDLKPFTEYVFRIRCMKE 304
+ DL P EYV I E
Sbjct 78 QTVLSDLIPEIEYVVSIASYDE 99
Score = 42.5 bits (98), Expect = 0.022, Method: Composition-based stats.
Identities = 14/100 (14%), Positives = 29/100 (29%), Gaps = 4/100 (4%)
Query 418 ACDFQATHPVMDLKAFPKDN-MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
+ P +L A + + + W + Y +++ + G
Sbjct 327 VSGEEVVEPASNLVATQISSKSVRITWDPSTSQITGYRVQFIPMIAGGKQHVL---SVGP 383
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+L+ Y I V + P P +I +Q
Sbjct 384 QTTALNVKDLSPDTEYQINVYAMKGLTPSEPITIMEKTQQ 423
>sp|P70211|DCC_MOUSE Netrin receptor DCC OS=Mus musculus OX=10090
GN=Dcc PE=1 SV=2
Length=1447
Score = 200 bits (509), Expect = 2e-51, Method: Composition-based stats.
Identities = 82/439 (19%), Positives = 147/439 (33%), Gaps = 39/439 (9%)
Query 200 AENALGKVTSDHINFDP-----VYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
AEN G S P + P+ P + V+ S ++L+W P+ I
Sbjct 402 AENEAGNAQSSAQLIVPKPAIPSSSILPSAPRD--VLPVLVSSRFVRLSWRPPAEAKGNI 459
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
+ + + + + + T TV +LKP Y FR+ E G G + S
Sbjct 460 QTFTVFFSREGDNRERALNT--TQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPG---ESS 514
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK 374
+ T + P + + + ++ + W+ PP ANG + Y + T
Sbjct 515 QPIKVATQPELQVPGP---VENLHAVSTSPTSILITWE--PPAYANGPVQGYRLFCTEVS 569
Query 375 SH-LQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAA--VLTIPACDFQATHPVMD 429
+ QN V+ + Y N G + + + D + P
Sbjct 570 TGKEQNIEVDGLSYKLEGLKKFTEYTLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNI 629
Query 430 LKAFPKDNMLWVEWTTPR-ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
+ V W P + +I + + K + + + YL L +
Sbjct 630 SLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLW-YLFTGLEK 688
Query 489 SKCYLITVTPVYADGPGSPESIKAYLKQAP---------PSKGPTVRTKKVGKNEAVLEW 539
Y V+ + +G G P + Y + P P + ++ + N ++ W
Sbjct 689 GSQYSFQVSAMTVNGTGPPSNW--YTAETPENDLDESQVPDQPSSLHVRPQT-NCIIMSW 745
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
P N +R Y I Y V VDS Y++ L S + Y++ + A+ + G
Sbjct 746 --TPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAG 803
Query 600 -GKDGPEFTFTTPKFAQGE 617
G E T +
Sbjct 804 EGVPLYESATTRSITDPTD 822
Score = 178 bits (450), Expect = 3e-44, Method: Composition-based stats.
Identities = 101/604 (17%), Positives = 194/604 (32%), Gaps = 80/604 (13%)
Query 42 SNFTAVCVLKEKCMDYFHVNANYIVWKTN-HFTIPKEQYTIINRTASSVTFTDIASLNIQ 100
+ C + K VN W N IP + + I+ + + + S
Sbjct 346 MDIEFECAVSGK--PVPTVN-----WMKNGDVVIPSDYFQIVGGSNLRILGV-VKSDEGF 397
Query 101 LTCNILTFGQLEQNVYGITI------ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRE--T 152
C Q+ + + S + P P+++ ++ + +R W E
Sbjct 398 YQCVAENEAGNAQSSAQLIVPKPAIPSSSILPSAPRDVLPVLVSSRFVRLSWRPPAEAKG 457
Query 153 HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-TSDH 211
+++T FT+ + + V A N G +S
Sbjct 458 NIQT-FTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQP 516
Query 212 INFDPVYKVK-PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS 270
I +++ P P NL +++ + + +TW P+ + + Y +
Sbjct 517 IKVATQPELQVPGPVENLHAVST--SPTSILITWEPPAYANGPVQGYRLFCTEVSTGKEQ 574
Query 271 QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
I + S+ ++ LK FTEY R G G +D + + +T D PS P
Sbjct 575 NIEVDGL-----SYKLEGLKKFTEYTLRFLAYNRYGPGVSTD---DITVVTLSDVPSAPP 626
Query 331 SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN 390
R++++ W P NG I Y++ + + T+ L
Sbjct 627 QNISL----EVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYL 682
Query 391 LT----NDRYLATLTVRNLVGKSDAA------VLTIPACDFQATHPVMDLKAFPKDNMLW 440
T +Y ++ + G + + Q L P+ N +
Sbjct 683 FTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTNCII 742
Query 441 VEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
+ WT P V+ YI+ + V S A + + R Y L S Y+I++
Sbjct 743 MSWTPPLNPNIVVRGYIIGYGVGSPYAETV-----RVDSKQRYYSIERLESSSHYVISLK 797
Query 498 PVYADGPGSP----ESIKAYLKQAPP---------------------SKGPTVRTKKVGK 532
G G P + ++ P V+ +
Sbjct 798 AFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSGPDVSTPMLPPVGVQAVALTH 857
Query 533 NEAVLEWDQ--LPVDVQNGFIRNYTIFYRTIIG-NETAVNVDSSHTEYTLSSLTSDTLYM 589
+ W +P + + +R YT+ +RT + + D++ YT + L +T+Y
Sbjct 858 EAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYE 917
Query 590 VRMA 593
+
Sbjct 918 FSVM 921
Score = 165 bits (418), Expect = 2e-40, Method: Composition-based stats.
Identities = 91/544 (17%), Positives = 166/544 (31%), Gaps = 62/544 (11%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSE 163
N G+ Q + T P +NL + + W+ +
Sbjct 506 NEWGPGESSQPIKVATQPELQVPGPVENLHAVSTSPTSILITWEPPAYANGPVQG--YRL 563
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKP 222
+ T + + F + A N G V++D I + V
Sbjct 564 FCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYTLRFLAYNRYGPGVSTDDITVVTLSDVPS 623
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIK--SVIILKYNIQYRTKDASTWSQIPPEDTAST 280
PP N+S+ S +K++W P + I Y I++R E
Sbjct 624 APPQNISLEVVN--SRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRG----EMETLEPN 677
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR--PSKAPSFWYKIDP 338
+ L+ ++Y F++ M +G G S+W + T E+ S+ P +
Sbjct 678 NLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNW---YTAETPENDLDESQVPDQPSSLHV 734
Query 339 SHTQGYRTVQLVWKTLPPFEAN----GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND 394
+ + W PP N G I+ Y V ++ + + ++
Sbjct 735 RPQTNC--IIMSW--TPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSS 790
Query 395 RYLATLTVRNLVGKS-----DAAVLTI--------------------PACDFQATHPVMD 429
Y+ +L N G+ A +I P PV
Sbjct 791 HYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSGPDVSTPMLPPVGV 850
Query 430 LKAFPKDNMLWVEW---TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
+ V W + P+ + + V + + + + T +Y L
Sbjct 851 QAVALTHEAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGL 910
Query 487 AESKCYLITVTPV-YADGPGSPESIKAYLKQAPPSKGP---TVRTKKVGKNEAVLEWDQL 542
+ Y +V + A +A P+ P TV T++ ++ W
Sbjct 911 KPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPRAVIVSWQ-- 968
Query 543 PVDVQNGFIRNYTIFYR----TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
P NG I Y +FY I + + + + L+ DT+Y R+ A +
Sbjct 969 PPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLSLDTMYYFRIQARNVK 1028
Query 599 GGKD 602
G
Sbjct 1029 GVGP 1032
Score = 137 bits (344), Expect = 2e-31, Method: Composition-based stats.
Identities = 72/331 (22%), Positives = 112/331 (34%), Gaps = 26/331 (8%)
Query 314 SEEASGITYEDRPSKA--PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
S + PS + PS + P R V+L W+ PP EA G I + V +
Sbjct 411 SSAQLIVPKPAIPSSSILPSAPRDVLPVLVSS-RFVRLSWR--PPAEAKGNIQTFTVFFS 467
Query 372 RWKSHLQNYTVNATKLTVNLT------NDRYLATLTVRN--LVGKSDAAVLTIPACDFQA 423
R + + ++ LT Y + N G+S + + Q
Sbjct 468 REGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQV 527
Query 424 THPVMDLKAFPKD-NMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
PV +L A + + W P V+ Y L +S Q +
Sbjct 528 PGPVENLHAVSTSPTSILITWEPPAYANGPVQGYRLFCTEVSTGKE-----QNIEVDGLS 582
Query 480 TYLRGNLAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVL 537
L G L + Y + GPG S + I PS P + + V +
Sbjct 583 YKLEG-LKKFTEYTLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNISLEVVNSRSIKV 641
Query 538 EWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
W P QNGFI Y I +R ++ ++ Y + L + Y +++A T
Sbjct 642 SWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTV 701
Query 598 EG-GKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
G G +T TP+ E + P L
Sbjct 702 NGTGPPSNWYTAETPENDLDESQVPDQPSSL 732
Score = 121 bits (302), Expect = 2e-26, Method: Composition-based stats.
Identities = 77/446 (17%), Positives = 151/446 (34%), Gaps = 54/446 (12%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG---GRETHLETNFTL 160
N G ++ +T+ S +P P+N+S V + ++ W G + T + +
Sbjct 602 NRYGPGVSTDDITVVTL-SDVPSAPPQNISLEVVNSRSIKVSWLPPPSGTQNGFITGYKI 660
Query 161 KSEWATHKFADCKAKRDTPTSC-TVDYSTVYFVNIEVWVEAENALGKVTSDHINF----- 214
+ T + + + P + + V A G +
Sbjct 661 RHRKTTRRG---EMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPE 717
Query 215 -DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
D P+ P +L V ++ + ++WT P ++++ Y I Y + +
Sbjct 718 NDLDESQVPDQPSSLHVRPQ---TNCIIMSWTPPLNPNIVVRGYIIGY-GVGSPYAETVR 773
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT-----------Y 322
S + ++++ L+ + YV ++ G+G S IT
Sbjct 774 ---VDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLL 830
Query 323 EDRPSKAPSFWYKIDP-----SHTQGYRTVQLVW--KTLPPFEANGKILDYEVTLTRWKS 375
+D P+ P + P + + V++ W ++P + + Y V S
Sbjct 831 DDFPTSGPDVSTPMLPPVGVQAVALTHEAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFS 890
Query 376 HLQNY-TVNATKLTVNLT----NDRYLATLTVRNLVGKSDAAVLTIPAC-DFQATHPVMD 429
Y + + T L+ T N Y ++ V S ++ + T D
Sbjct 891 ASAKYKSEDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKD 950
Query 430 LKAFPKDN---MLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHR-TYL 482
L ++ + V W P E+ + YIL + + DK I DW E + R T+
Sbjct 951 LTVITREGKPRAVIVSWQPPLEANGKITAYILFYTL--DKNIPIDDWIMETISGDRLTHQ 1008
Query 483 RGNLAESKCYLITVTPVYADGPGSPE 508
+L+ Y + G G
Sbjct 1009 IMDLSLDTMYYFRIQARNVKGVGPLS 1034
Score = 81.1 bits (198), Expect = 4e-14, Method: Composition-based stats.
Identities = 41/199 (21%), Positives = 68/199 (34%), Gaps = 9/199 (5%)
Query 122 SGLPPEKPKNLSCIVNEGKKMRCEW-DGGRETHLETN----FTLKSEWATHKFADCKAKR 176
P P + + + +R W D + +T+ +T++ W T A K K
Sbjct 840 VSTPMLPPVGVQAVALTHEAVRVSWADNSVPKNQKTSDVRLYTVR--WRTSFSASAKYKS 897
Query 177 DTPTSCTVDYSTVY-FVNIEVWVEAE-NALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
+ TS + + + E V N S + + P +L+VI E
Sbjct 898 EDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITRE 957
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ ++W P + I Y + Y E + R + + DL T
Sbjct 958 GKPRAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLSLDTM 1017
Query 295 YVFRIRCMKEDGKGYWSDW 313
Y FRI+ G G SD
Sbjct 1018 YYFRIQARNVKGVGPLSDP 1036
>sp|P14787|PRLR_RABIT Prolactin receptor OS=Oryctolagus cuniculus
OX=9986 GN=PRLR PE=1 SV=1
Length=616
Score = 193 bits (489), Expect = 7e-51, Method: Composition-based stats.
Identities = 67/238 (28%), Positives = 101/238 (42%), Gaps = 21/238 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKS----EWATHKFADCKAKRDTPT 180
PP KP C E + C W G + L TN+TL E TH+ D K P
Sbjct 27 PPGKPFIFKCRSPEKETFTCWWRPGADGGLPTNYTLTYHKEGETITHECPDY--KTGGPN 84
Query 181 SCTVDYSTVYFVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEELS 237
SC + V A N +G SD D Y V+P+PP NL+ V + E+
Sbjct 85 SCYFSKKHTSIWTIYIITVNATNQMGSSVSDPRYVDVTYIVEPDPPVNLTLEVKHPEDRK 144
Query 238 SILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
L + W P++ V + L+Y I+ + + A+ W A ++ F + L P
Sbjct 145 PYLWVKWLPPTLVDVRSGWLTLQYEIRLKPEKAAEWET----HFAGQQTQFKILSLYPGQ 200
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
+Y+ ++RC + G+WS WS E+S D K + W + T + +VW
Sbjct 201 KYLVQVRCKPD--HGFWSVWSPESSIQIPNDFTMKDITVWIFVAVLSTIIC--LIMVW 254
Score = 57.9 bits (138), Expect = 4e-07, Method: Composition-based stats.
Identities = 58/297 (20%), Positives = 96/297 (32%), Gaps = 30/297 (10%)
Query 490 KCYLITVTPVYADGPGSPES---IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV-- 544
Y+ITV G + Y+ + P T+ K + L LP
Sbjct 97 TIYIITVNATNQMGSSVSDPRYVDVTYIVEPDPPVNLTLEVKHPEDRKPYLWVKWLPPTL 156
Query 545 -DVQNGFIR-NYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG--G 600
DV++G++ Y I + E + T++ + SL Y+V++ D G
Sbjct 157 VDVRSGWLTLQYEIRLKPEKAAEWETHFAGQQTQFKILSLYPGQKYLVQVRCKPDHGFWS 216
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
PE + P + + + V + + L+ V K + I+P VP P
Sbjct 217 VWSPESSIQIPNDFTMKDITVWIFVAVLSTIICLIMVWAVALKGYSMVTCIFPPVPGP-- 274
Query 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSV-----VEIEANDKK------PFPEDLK 709
I + H + + +F + VE D P
Sbjct 275 -KIKGFDTHLLEKGKSEELLSAFGCQDFPPTADCEDLLVEFLEVDDSEDQQLMPAHSKEH 333
Query 710 SLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSG 766
S K ++ + S G SC S S S++ E Q ST V+
Sbjct 334 SGPGMKPTDLDPDNDS---GRGSCDSPS----LLSEKCEEPQANPSTFHTPEVIEQP 383
Score = 42.2 bits (97), Expect = 0.025, Method: Composition-based stats.
Identities = 31/196 (16%), Positives = 52/196 (27%), Gaps = 16/196 (8%)
Query 330 PSFWYKIDPSHTQGYRTVQLVWKT-LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLT 388
P I + T W+ L Y +Y
Sbjct 27 PPGKPFIFKCRSPEKETFTCWWRPGADGGLPTNYTLTYHKEGETITHECPDYKTGGPNSC 86
Query 389 VNLTN-----DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM----- 438
Y+ T+ N +G S + + P ++L K
Sbjct 87 YFSKKHTSIWTIYIITVNATNQMGSSVSDPRYVDVTYIVEPDPPVNLTLEVKHPEDRKPY 146
Query 439 LWVEWTTPR--ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV 496
LWV+W P + ++ + K +W+ + +L + YL+ V
Sbjct 147 LWVKWLPPTLVDVRSGWLTLQYEIRLKPEKAAEWETHFAGQQTQFKILSLYPGQKYLVQV 206
Query 497 TPVYADG---PGSPES 509
G SPES
Sbjct 207 RCKPDHGFWSVWSPES 222
>sp|O46561|PRLR_SHEEP Prolactin receptor OS=Ovis aries OX=9940
GN=PRLR PE=2 SV=1
Length=581
Score = 191 bits (485), Expect = 1e-50, Method: Composition-based stats.
Identities = 62/221 (28%), Positives = 97/221 (44%), Gaps = 15/221 (7%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHK-FADCK-AKRDTPTSC 182
PPEKPK + C + C W+ G + L TN+TL +C K P SC
Sbjct 27 PPEKPKLIKCRSPGKETFTCWWEPGADGGLPTNYTLTYRKEGETLIHECPDYKTGGPNSC 86
Query 183 TVDYSTVYFVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV--INSEELSSI 239
+ V A N +G +SD + D Y V+P PP NL++ + E+
Sbjct 87 YFSKKYTSIWKMYVITVSAINQMGISSSDPLYVDVTYIVEPEPPVNLTLELKHPEDRKPY 146
Query 240 LKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
L + W+ P++ V ++Y I+ + + A+ W A + + +L P +Y
Sbjct 147 LWIKWSPPTLTDVKSGWFSIQYEIRLKPEKATDWET----HFAPKLTQLKIFNLYPGQKY 202
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ +IRC + GYWS+WS E+ D P K S W +
Sbjct 203 LVQIRCKPD--HGYWSEWSPESFIQIPNDFPVKDTSMWIFV 241
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 55/350 (16%), Positives = 97/350 (28%), Gaps = 40/350 (11%)
Query 490 KCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-----TVRTKKVGKNEAVLEWDQLPV 544
K Y+ITV+ + G S + + + + P ++ + K ++W +
Sbjct 97 KMYVITVSAINQMGISSSDPLYVDVTYIVEPEPPVNLTLELKHPEDRKPYLWIKWSPPTL 156
Query 545 DVQNG--FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
F Y I + + + T+ + +L Y+V++ D G
Sbjct 157 TDVKSGWFSIQYEIRLKPEKATDWETHFAPKLTQLKIFNLYPGQKYLVQIRCKPDHGYWS 216
Query 603 --GPEFTFTT----PKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVP 656
PE P + V + L+ L ++ I P VP
Sbjct 217 EWSPESFIQIPNDFPVKDTSMWIFVGVLSAVICLIMVWAVALKGYSMVTCIL----PPVP 272
Query 657 DPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKK 716
P I + H + + +F S E E ++ D +
Sbjct 273 GP---KIKGFDIHLLEKGKSEELLRALESQDFLPTSDCEDL------LMEFIEVDDSEDQ 323
Query 717 EKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQV 776
+ G M + S +S S + +P
Sbjct 324 HLMPHPSKEHMEQGVKPMHLDPDTDSGRGSCDSPSLLSEKCDEPQAY--PSKFHIP---- 377
Query 777 FSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSP 826
E + L D E LQ G I YF N + + P
Sbjct 378 ----EGPEKLEDPETNHTCLQAPQSTSGEGKI----PYFLANGPKSSTWP 419
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 36/203 (18%), Positives = 73/203 (36%), Gaps = 21/203 (10%)
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL-------QNYTV 382
P K+ + G T W+ P G +Y +T + L +
Sbjct 27 PPEKPKLIKCRSPGKETFTCWWE---PGADGGLPTNYTLTYRKEGETLIHECPDYKTGGP 83
Query 383 NATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA-----FPK 435
N+ + T+ Y+ T++ N +G S + L + P ++L +
Sbjct 84 NSCYFSKKYTSIWKMYVITVSAINQMGISSSDPLYVDVTYIVEPEPPVNLTLELKHPEDR 143
Query 436 DNMLWVEWTTPRESVKK---YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
LW++W+ P + K + +++ + K TDW+ NL + Y
Sbjct 144 KPYLWIKWSPPTLTDVKSGWFSIQYEIRL-KPEKATDWETHFAPKLTQLKIFNLYPGQKY 202
Query 493 LITVTPVYADGPGSPESIKAYLK 515
L+ + G S S +++++
Sbjct 203 LVQIRCKPDHGYWSEWSPESFIQ 225
>sp|Q9VN14|CONT_DROME Contactin OS=Drosophila melanogaster OX=7227
GN=Cont PE=1 SV=2
Length=1390
Score = 197 bits (501), Expect = 2e-50, Method: Composition-based stats.
Identities = 116/609 (19%), Positives = 192/609 (32%), Gaps = 73/609 (12%)
Query 43 NFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLT 102
N T VC D WK + I + I + + T
Sbjct 774 NTTIVC-------DPEAAPRPKFQWKKDGQVIGSGGHRRILPSGTLTISPTSRDDEGIYT 826
Query 103 CNILT-FGQLEQNVYGITI-ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL 160
C G E + I + P+ + ++ + CE + L+ +
Sbjct 827 CIASNQAGTDESHARVIVLQEIRFIETPPQRIVSKEHDLIFLHCE--AAFDELLDIAYVW 884
Query 161 KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN--------IEVWV-EAENALGKVTSDH 211
K H K D VD++ + N E V A N + TS
Sbjct 885 K-----HNGEVLKNNHDGTGRIIVDWNRLTVHNTSMRDAGDYECVVKSAVNEISSKTSVS 939
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQ 271
I + P P + VI + +I++ W + S I YNI RT TW
Sbjct 940 I------EGAPGAPGGVQVIQISKTKAIIE--WVDGSHNGRAIRYYNILGRTNWNRTWVN 991
Query 272 IPPE------DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
+ D ++R V +L P++ Y F + + + G G S S S TYED+
Sbjct 992 VSTHVQAREVDRYTSRQQAEVVNLTPWSAYEFSVTAVNDLGIGTPSAPSPIYS--TYEDK 1049
Query 326 PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT-----RWKSHL--- 377
P AP + + W L P E + + Y+V W S
Sbjct 1050 PYIAPRNVGG----GGGKIGDLTITWDPLLPQEQHSHGIHYKVFWKLKGAIEWASDEIKK 1105
Query 378 QNYT-VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI--PACDFQATHPVMDLKAFP 434
Q++ V + +N Y + N VGK + + + A D P +
Sbjct 1106 QDHMGVAVVNIPLNNYYTEYEVKVQAINSVGKGPESEIAVIHSAEDMPQVAPQKPIALAY 1165
Query 435 KDNMLWVEWTT-------PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
V W R + + L++ + + + T + + G L
Sbjct 1166 NSTCFNVTWQPIDMSRENIRGKLIGHRLKYWKTTHQEEDSVYYLSRT-TRNWALIVG-LQ 1223
Query 488 ESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVD 545
Y + V A G G E + + P K P +V + + + W +
Sbjct 1224 PDTYYFVKVMAYNAAGEGPESERFEERTYRKAPQKPPSSVHVYGINPSTVRVVWRYVSPS 1283
Query 546 VQNGFIRNYTIFYRTIIG-----NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
+ Y + N T V + Y +++LT Y +R+ AY++ G
Sbjct 1284 QDEEPVEGYKVRIWESDQNMITANNTIVPIGQKLESY-INNLTPGKSYNMRVLAYSNGGD 1342
Query 601 KDGPEFTFT 609
T
Sbjct 1343 GRMSSPTLH 1351
>sp|O75445|USH2A_HUMAN Usherin OS=Homo sapiens OX=9606 GN=USH2A
PE=1 SV=3
Length=5202
Score = 196 bits (498), Expect = 6e-50, Method: Composition-based stats.
Identities = 110/553 (20%), Positives = 179/553 (32%), Gaps = 68/553 (12%)
Query 141 KMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
+ W +++ + + +F R T S + F ++A
Sbjct 3516 TIVLNWRKPIQSNGPIIYYILLRNGIERF------RGTSLSFSDKEGIQPFQEYSYQLKA 3569
Query 201 ENALGKVTSDHINFDPVYKVKP--NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
G TS + V PP ++ L L+W+ P + +I +Y
Sbjct 3570 CTVAGCATSSKVVAATTQGVPESILPPSITALSAV-----ALHLSWSVPEKSNGVIKEYQ 3624
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
I+ K + DT R TV L+P+T Y F + G SE
Sbjct 3625 IRQVGKG------LIHTDTTD-RRQHTVTGLQPYTNYSFTLTACTSAG----CTSSEPFL 3673
Query 319 GITYEDRPSKAPSFWYKIDPSH-TQGYRTVQLVWKTLPPFEANGKILDYEVT-----LTR 372
G T + P W + P H TV+L W P + NG + Y+++ L
Sbjct 3674 GQTLQAAPEG---VW--VTPRHIIINSTTVELYWS--LPEKPNGLVSQYQLSRNGNLLFL 3726
Query 373 WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK--SDAAVLTIPACDFQATHPVMDL 430
S QN+T + N RY L V+ G SD ++ P + +P ++
Sbjct 3727 GGSEEQNFTDKNLE-----PNSRYTYKLEVKTGGGSSASDDYIVQTPMSTPEEIYPPYNI 3781
Query 431 KAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
+ ++V W P + + +E+ VL + H++ L NL
Sbjct 3782 TVIGPYS-IFVAWIPPGILIPEIPVEYNVLLNDGSVTP--LAFSVGHHQSTLLENLTPFT 3838
Query 491 CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
Y I + G + +A P + K +G ++W +P + NG
Sbjct 3839 QYEIRIQACQNGSCGVSSRMFVKTPEAAPMDLNSPVLKALGSACIEIKW--MPPEKPNGI 3896
Query 551 IRNYTIFYRTIIGNETAVNVDSSHTEYTLSS----LTSDTLYMVRMAAYTDEGGKDGPEF 606
I NY I+ R E +V S L TLY R+ A +G +
Sbjct 3897 IINYFIYRRPAGIEEESVLFVWSEGALEFMDEGDTLRPFTLYEYRVRACNSKGSVESLWS 3956
Query 607 TFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQW 666
T + + A A ++ P P+ SH
Sbjct 3957 LTQTLEAPPQDFPAPWAQATSAH---------------SVLLNWTKPESPNGIISHYRVV 4001
Query 667 SPHTPPRHNFNSK 679
P FNS
Sbjct 4002 YQERPDDPTFNSP 4014
Score = 193 bits (490), Expect = 7e-49, Method: Composition-based stats.
Identities = 92/465 (20%), Positives = 150/465 (32%), Gaps = 51/465 (11%)
Query 167 HKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH 226
K + + T D + E + N+ G S + PP
Sbjct 4209 EKIVFTEYNTERNTFMYNDTGLQPWTQCEYKIYTWNSAGHTCSSWNVVRTLQ----APPE 4264
Query 227 NLS---VINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
LS + L ++W P + II Y +Q + P +
Sbjct 4265 GLSPPVISYVSMNPQKLLISWIPPEQSNGIIQSYRLQRN-------EMLYPFSFDPVTFN 4317
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK--APSFWYKIDPSHT 341
+T ++L PF+ Y + ++ G S+ S T E PS+ P W
Sbjct 4318 YTDEELLPFSTYSYALQACTSGGCST----SKPTSITTLEAAPSEVSPPDLWAV------ 4367
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLT 401
+ + W PP NGKI Y V +S ++ +Y +L
Sbjct 4368 -SATQMNVCWS--PPTVQNGKITKYLVRYDNKESLAGQGLCLL--VSHLQPYSQYNFSLV 4422
Query 402 VRNLVGKSDAAVLTIPACDFQATHPVMDLKA--FPKDNMLWVEWTTPRESVKKYILEWCV 459
G + A ++ A +A MD + + W PR I + +
Sbjct 4423 ACTNGGCT--ASVSKSAWTMEALPENMDSPTLQVTGSESIEITWKPPRNP-NGQIRSYEL 4479
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
D + Y L Y TVT + G +K + P
Sbjct 4480 RRDG-------TIVYTGLETRYRDFTLTPGVEYSYTVTASNSQGGILSPLVKDRTSPSAP 4532
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA-VNVDSSHT--- 575
S + + G E ++ WD P NG I NYT+F R + ET ++++++H
Sbjct 4533 SGMEPPKLQARGPQEILVNWD--PPVRTNGDIINYTLFIRELFERETKIIHINTTHNSFG 4590
Query 576 --EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEI 618
Y ++ L Y +R+ A T G TP+ A
Sbjct 4591 MQSYIVNQLKPFHRYEIRIQACTTLGCASSDWTFIQTPEIAPLMQ 4635
Score = 180 bits (456), Expect = 9e-45, Method: Composition-based stats.
Identities = 95/548 (17%), Positives = 163/548 (30%), Gaps = 63/548 (11%)
Query 109 GQLEQNVYGITIISGLPPE--KPKNLSCIVNEGKKMRCEWDGG-RETHLETNFTLKSEWA 165
G + Y + P E P N++ ++ G + + +
Sbjct 3756 GSSASDDYIVQTPMSTPEEIYPPYNIT-VIGPYSIFVAWIPPGILIPEIPVEYNVLLNDG 3814
Query 166 THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA-ENALGKVTSDHINFDPVYKVKPNP 224
+ A T+ + F E+ ++A +N S ++ K
Sbjct 3815 SVTPL---AFSVGHHQSTLLENLTPFTQYEIRIQACQNG-----SCGVSSRMFVKTPEAA 3866
Query 225 PHNL-SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P +L S + S+ +++ W P + II+ Y I R S + +
Sbjct 3867 PMDLNSPVLKALGSACIEIKWMPPEKPNGIIINYFIYRRPAGIEEESVLFVWSEGALEFM 3926
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
L+PFT Y +R+R G S WS T E P P+ W + +H
Sbjct 3927 DEGDTLRPFTLYEYRVRACNSKG-SVESLWS---LTQTLEAPPQDFPAPWAQATSAH--- 3979
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN---------- 393
+V L W P NG I Y V + TV T+
Sbjct 3980 --SVLLNW--TKPESPNGIISHYRVVYQERPDDPTFNSPTVHAFTVKGTSHQAHLYGLEP 4035
Query 394 -DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM--LWVEWTTPRESV 450
Y + N G+ + I + + + + K+N L ++W+ P
Sbjct 4036 FTTYRIGVVAANHAGEILSPWTLIQTLE-SSPSGLRNFIVEQKENGRALLLQWSEPM-RT 4093
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
I + + SD E ++R +L L Y +T+ G
Sbjct 4094 NGVIKTYNIFSDGFL-------EYSGLNRQFLFRRLDPFTLYTLTLEACTRAGCAHSAPQ 4146
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE----- 565
+ +APP V L W + NG I Y + R G
Sbjct 4147 PLWTDEAPPDSQLAPTVHSVKSTSVELSWSE--PVNPNGKIIRYEVIRRCFEGKAWGNQT 4204
Query 566 ---------TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
T N + + Y + L T ++ + G T +
Sbjct 4205 IQADEKIVFTEYNTERNTFMYNDTGLQPWTQCEYKIYTWNSAGHTCSSWNVVRTLQAPPE 4264
Query 617 EIEAIVVP 624
+ V+
Sbjct 4265 GLSPPVIS 4272
Score = 172 bits (435), Expect = 3e-42, Method: Composition-based stats.
Identities = 89/519 (17%), Positives = 174/519 (34%), Gaps = 49/519 (9%)
Query 142 MRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
M W + + T++ + + T+CTV + Y + VEA
Sbjct 2549 MLVTWQHPRKSNGVITHYNIY--LHGRLYLRTPGNV---TNCTVMHLHPY-TAYKFQVEA 2602
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNL-SVINSEELSSILKLTWTNPSIKSVIILKYNI 259
+ G S P P + S + + + ++W P+ + ++ + I
Sbjct 2603 CTSKGCSLSPE---SQTVWTLPGAPEGIPSPELFSDTPTSVIISWQPPTHPNGLVENFTI 2659
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQD----LKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+ R K ++ T S D L P+T+Y +R+ G S W E
Sbjct 2660 ERRVKGKE---EVTTLVTLPRSHSMRFIDKTSALSPWTKYEYRVLMSTLHGGTNSSAWVE 2716
Query 316 EASGITYEDRPSK-APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK 374
T RP+ P ++P VQ+ WK PP NG IL YE+ +
Sbjct 2717 ---VTTRPSRPAGVQPPVVTVLEPD------AVQVTWK--PPLIQNGDILSYEIHMPDPH 2765
Query 375 SHLQNYT--VNATKLTVNLTNDRYLATLTVRNL----VGKSDAAVLTIPACDFQATHPVM 428
L N T V + K+T + Y T+ + +G ++ T V
Sbjct 2766 ITLTNVTSAVLSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTESLPTYVTTHPTVPQNVG 2825
Query 429 DLKAFP-KDNMLWVEWTTPRES--------VKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
L P ++ + + W P + + + ++ + S+ + W
Sbjct 2826 PLSVIPLSESYVVISWQPPSKPNGPNLRYELLRRKIQQPLASNPPEDLNRWHNIYSGTQW 2885
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
Y L+ Y + + G + P +G + + + W
Sbjct 2886 LYEDKGLSRFTTYEYMLFVHNSVGFTPSREVTVTTLAGLPERGANLTASVLNHTAIDVRW 2945
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ V G + YT+F+ + N+ ++ + + + L +T Y + ++ +
Sbjct 2946 AKPTVQDLQGEVEYYTLFWSSATSND-SLKILPDVNSHVIGHLKPNTEYWIFISVFNGVH 3004
Query 600 GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
+ TT GE + ++ P + T + +
Sbjct 3005 SINSAGLHATT---CDGEPQGMLPPEVVIINSTAVRVIW 3040
Score = 169 bits (428), Expect = 2e-41, Method: Composition-based stats.
Identities = 100/532 (19%), Positives = 168/532 (32%), Gaps = 54/532 (10%)
Query 129 PKNL---SCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P+N+ + V + + W R + + T + + + D
Sbjct 4444 PENMDSPTLQVTGSESIEITWKPPRNPNGQIRSYELRRDGTIVYTGLETR-------YRD 4496
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV-INSEELSSILKLTW 244
++ V V A N+ G + S + + P+ P + + + W
Sbjct 4497 FTLTPGVEYSYTVTASNSQGGILSPLVK----DRTSPSAPSGMEPPKLQARGPQEILVNW 4552
Query 245 TNPSIKSVIILKYNIQYRTKDASTWS--QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
P + I+ Y + R I + S+ V LKPF Y RI+
Sbjct 4553 DPPVRTNGDIINYTLFIRELFERETKIIHINTTHNSFGMQSYIVNQLKPFHRYEIRIQAC 4612
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
G SDW T E P P ++ + TV L+W P + NGK
Sbjct 4613 TTLGC-ASSDW---TFIQTPEIAPLMQPPPHLEVQMAPGGFQPTVSLLWTG--PLQPNGK 4666
Query 363 ILDYEVTLTRWKSHLQNYTV----NATKLTV----NLTNDRYLATLTVRNLVGKSDAAVL 414
+L YE+ + + + N + + L Y + N GK+ ++
Sbjct 4667 VLYYELYRRQIATQPRKSNPVLIYNGSSTSFIDSELLPFTEYEYQVWAVNSAGKAPSSW- 4725
Query 415 TIPACDFQATHPVMDLKA----FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW 470
P L+A V + P + + + + S A
Sbjct 4726 ---TWCRTGPAPPEGLRAPTFHVISSTQAVVNISAPGKP-NGIVSLYRLFSSSAHGAETV 4781
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-ESIKAYLKQAPPSKGPTVRTKK 529
E G + L G L Y I V S + + APPS + +
Sbjct 4782 LSE-GMATQQTLHG-LQAFTNYSIGVEACTCFNCCSKGPTAELRTHPAPPSGLSSPQIGT 4839
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH--TEYT-------LS 580
+ A W P NG I +Y + + ++A+ S T+YT L
Sbjct 4840 LASRTASFRWS--PPMFPNGVIHSYELQFHVACPPDSALPCTPSQIETKYTGLGQKASLG 4897
Query 581 SLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLT 632
L T Y +R+ A+ + G +FTT K V L+ +
Sbjct 4898 GLQPYTTYKLRVVAHNEVGSTASEWISFTTQKELPQYRAPFSVDSNLSVVCV 4949
Score = 148 bits (374), Expect = 7e-35, Method: Composition-based stats.
Identities = 71/440 (16%), Positives = 125/440 (28%), Gaps = 62/440 (14%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP V + SS + L+W+ P + L Y++ + ED
Sbjct 1058 PPPRGQV----QSSSAINLSWSPPDSPNAHWLTYSL-----LRDGFEIYTTEDQYPYSIQ 1108
Query 284 FTV-QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
+ + DL P+T+Y + I G S S + T P + Y I
Sbjct 1109 YFLDTDLLPYTKYSYYIETTNVHG----STRSVAVTYKTKPGVPEGNLTLSYII----PI 1160
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV----NLTNDRYLA 398
G +V L W TL +G I Y ++ + + + + +Y
Sbjct 1161 GSDSVTLTWTTL--SNQSGPIEKYILSCAPLAGGQPCVSYEGHETSATIWNLVPFAKYDF 1218
Query 399 TLTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
++ G S +T Q P K L VEW+ P E + I+
Sbjct 1219 SVQACTSGGCLHSLPITVTTAQAPPQRLSPPKMQKI--SSTELHVEWSPPAE-LNGIIIR 1275
Query 457 WCVLSDKAPCITD-------------WQQEDGTVHRTY-----------LRGNLAESKCY 492
+ + + + W V L Y
Sbjct 1276 YELYMRRLRSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKY 1335
Query 493 LITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
V V G S + ++ P + + W++ +V G +
Sbjct 1336 EFRVLAVNMAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYSLNISWEKPADNVTRGKVV 1395
Query 553 NYTIFYRTIIGNETAVNV---------DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
Y I + + ++ + S YT+ L +Y + G
Sbjct 1396 GYDINMLSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIYEFTITLCNSVGCVTS 1455
Query 604 PEFTFTTPKFAQGEIEAIVV 623
T A ++ +V
Sbjct 1456 ASGAGQTLAAAPAQLRPPLV 1475
Score = 148 bits (373), Expect = 9e-35, Method: Composition-based stats.
Identities = 100/643 (16%), Positives = 178/643 (28%), Gaps = 62/643 (10%)
Query 13 FIFLTTESTGELLDPCGYI------SPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIV 66
++F S G +I PVV + + + H + V
Sbjct 2506 YMFRLVASNGFGSAHSSWIPFMTAEDKPGPVVP---PILLDVKSRMMLVTWQHPRKSNGV 2562
Query 67 WKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLT----CNILTFGQLEQNVYGITIIS 122
+ + Y ++ T + C ++ T+
Sbjct 2563 ITHYNIYLHGRLYLRTPGNVTNCTVMHLHPYTAYKFQVEACTSKGCSLSPESQTVWTLP- 2621
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGR-ETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
G P P + + W L NFT++ + S
Sbjct 2622 GAPEGIPS-PELFSDTPTSVIISWQPPTHPNGLVENFTIERRVKGKEEVTTLVTLPRSHS 2680
Query 182 CTV-DYSTVY--FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL-- 236
D ++ + E V G S +V P V
Sbjct 2681 MRFIDKTSALSPWTKYEYRVLMSTLHGGTNSS-----AWVEVTTRPSRPAGVQPPVVTVL 2735
Query 237 -SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+++TW P I++ IL Y I I + S S V L PFT Y
Sbjct 2736 EPDAVQVTWKPPLIQNGDILSYEI------HMPDPHITLTNVTSAVLSQKVTHLIPFTNY 2789
Query 296 VFR-IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
+ C +G S T+ P V + W+
Sbjct 2790 SVTIVACSGGNGYLGGCTESLPTYVTTHPTVPQNVGPLSVI-----PLSESYVVISWQ-- 2842
Query 355 PPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN--------------DRYLATL 400
PP + NG L YE+ + + L + N+ + Y L
Sbjct 2843 PPSKPNGPNLRYELLRRKIQQPLASNPPEDLNRWHNIYSGTQWLYEDKGLSRFTTYEYML 2902
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
V N VG + + +T+ + + V W P + +E+ L
Sbjct 2903 FVHNSVGFTPSREVTVTTLAGLPERGANLTASVLNHTAIDVRWAKPTVQDLQGEVEYYTL 2962
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS 520
+ D + V+ ++ G+L + Y I ++ + + A P
Sbjct 2963 FWSSATSNDSLKILPDVNS-HVIGHLKPNTEYWIFISVFNGVHSINSAGLHATTCDGEPQ 3021
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLS 580
+ + W NG + Y+I+ + T +NV S + L
Sbjct 3022 GMLPPEVVIINSTAVRVIW--TSPSNPNGVVTEYSIYVNNKLYK-TGMNVPGS---FILR 3075
Query 581 SLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
L+ T+Y +++ T TT + +I +
Sbjct 3076 DLSPFTIYDIQVEVCTIYACVKSNGTQITTVEDTPSDIPTPTI 3118
Score = 146 bits (367), Expect = 5e-34, Method: Composition-based stats.
Identities = 92/593 (16%), Positives = 170/593 (29%), Gaps = 87/593 (15%)
Query 44 FTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTC 103
T C+ + + Y NYIV T+ Q+ +
Sbjct 2085 ITQYCLYMDGRLIYSGSEENYIV--TDLAVFTPHQFLLSA------------------CT 2124
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD-GGRETHLETNFTLKS 162
++ +Y + PPE + V + + + +W + + + + L
Sbjct 2125 HVGCTNSSWVLLYTAQL----PPEHVDSPVLTVLDSRTIHIQWKQPRKISGILERYVLYM 2180
Query 163 EWATHKFADCKAKRDTPTSCTVDYSTVYFV---NIEVWVEAENALG---KVTSDHINFDP 216
TH F + T D+ Y + + + A G S+ + +
Sbjct 2181 SNHTHDFT-IWSVIYNSTELFQDHMLQYVLPGNKYLIKLGACTGGGCTVSEASEALTDED 2239
Query 217 VYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPED 276
+ + P P ++WT P + +I Y +
Sbjct 2240 IPEGVPAP------KAHSYSPDSFNVSWTEPEYPNGVITSYGL----------YLDGILI 2283
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
S+ S+ P++ + FR++ G T E P + + K
Sbjct 2284 HNSSELSYRAYGFAPWSLHSFRVQACTAKGCAL----GPLVENRTLEAPPEGTVNVFVK- 2338
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEV------------TLTRWKSHLQNYTVNA 384
TQG R + W+ PF NG + + T Y+
Sbjct 2339 ----TQGSRKAHVRWEA--PFRPNGLLTHSVLFTGIFYVDPVGNNYTLLNVTKVMYSGEE 2392
Query 385 TKLTVNLTN----DRYLATLTVRNLVGK--SDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
T L V + Y + + N G +D + +P P A P
Sbjct 2393 TNLWVLIDGLVPFTNYTVQVNISNSQGSLITDPITIAMPPGAPDGVLPPRLSSATPTS-- 2450
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQ--EDGTVHRTYLRGNLAESKCYLITV 496
L V W+TP + + + + + + + +Y +L Y+ +
Sbjct 2451 LQVVWSTPARNNAPGSPRYQLQMRSGDSTHGFLELFSNPSASLSYEVSDLQPYTEYMFRL 2510
Query 497 TPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
G I + P V ++ W NG I +Y I
Sbjct 2511 VASNGFGSAHSSWIPFMTAEDKPGPVVPPILLDVKSRMMLVTWQH--PRKSNGVITHYNI 2568
Query 557 FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT 609
+ + + + T T+ L T Y ++ A T +G PE
Sbjct 2569 Y----LHGRLYLRTPGNVTNCTVMHLHPYTAYKFQVEACTSKGCSLSPESQTV 2617
Score = 145 bits (366), Expect = 6e-34, Method: Composition-based stats.
Identities = 83/467 (18%), Positives = 145/467 (31%), Gaps = 70/467 (15%)
Query 138 EGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY--FVNIE 195
+ W L F + P S T +
Sbjct 1066 SSSAINLSWSPPDS---PNAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLPYTKYS 1122
Query 196 VWVEAENALGKVTSDHINFDPVYKVKPNPPH-NLSVINS-EELSSILKLTWTNPSIKSVI 253
++E N G S YK KP P NL++ S + LTWT S +S
Sbjct 1123 YYIETTNVHGSTRS----VAVTYKTKPGVPEGNLTLSYIIPIGSDSVTLTWTTLSNQSGP 1178
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
I KY + P +S T+ +L PF +Y F ++ G +
Sbjct 1179 IEKYILSCAPLAGGQ----PCVSYEGHETSATIWNLVPFAKYDFSVQACTSGGCLH---- 1230
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
S + T + P + + P Q + +L + PP E NG I+ YE+ + R
Sbjct 1231 SLPITVTTAQAPPQR-------LSPPKMQKISSTELHVEWSPPAELNGIIIRYELYMRRL 1283
Query 374 KSHLQNYTVNA-----------------------------TKLTVNLTNDRYLATLTVRN 404
+S + + + T +T +Y + N
Sbjct 1284 RSTKETTSEESRVFQSSGWLSPHSFVESANENALKPPQTMTTITGLEPYTKYEFRVLAVN 1343
Query 405 LVGKSDAAVLTIPACDFQAT--HPVMDLKAFPKDNMLWVEWTTPRESV-KKYILEW--CV 459
+ G +A ++ + P L + W P ++V + ++ + +
Sbjct 1344 MAGSVSSAWVSERTGESAPVFMIPPSVFPLSSYS--LNISWEKPADNVTRGKVVGYDINM 1401
Query 460 LSDKAPC------ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
LS+++P + + +Y L + Y T+T + G + S
Sbjct 1402 LSEQSPQQSIPMAFSQLLHTAKSQELSYTVEGLKPYRIYEFTITLCNSVGCVTSASGAGQ 1461
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
A P++ K + L W P + NG Y + R
Sbjct 1462 TLAAAPAQLRPPLVKGINSTTIHLRW--FPPEELNGPSPIYQLERRE 1506
Score = 143 bits (360), Expect = 3e-33, Method: Composition-based stats.
Identities = 103/641 (16%), Positives = 204/641 (32%), Gaps = 67/641 (10%)
Query 168 KFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHN 227
+ D + F V A + G V SD + P
Sbjct 1901 RGNDSILVYQGKEQSVYEGGLQPFTEYLYRVIASHEGGSVYSDWSRGRTTGAAPQSVPTP 1960
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP---PEDTASTRSSF 284
V + S +++TW P ++ +I KY ++ ++D++ ++P E ++ +
Sbjct 1961 SRVRSLNGYS--IEVTWDEPVVR-GVIEKYILKAYSEDSTRPPRMPSASAEFVNTSNLTG 2017
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGY 344
+ L PF Y + G ++ S + T ++ P + K PS
Sbjct 2018 ILTGLLPFKNYAVTLTACTLAGC---TESSHALNISTPQEAPQEVQPPVAKSLPSSLLLS 2074
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTR---WKSHLQNYTVNATKLTVNLTNDRYLATLT 401
W PP +ANG I Y + + + +NY V + + L+
Sbjct 2075 ------WN--PPKKANGIITQYCLYMDGRLIYSGSEENYIVTDLAVF-----TPHQFLLS 2121
Query 402 VRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES---VKKYILEWC 458
VG ++++ + + H + + ++W PR+ +++Y+L
Sbjct 2122 ACTHVGCTNSSWVLLYTAQLPPEHVDSPVLTVLDSRTIHIQWKQPRKISGILERYVLYMS 2181
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ + L+ L YLI + G E+ +A +
Sbjct 2182 NHTHDFTIWSVIYNSTELFQDHMLQYVL-PGNKYLIKLGACTGGGCTVSEASEALTDEDI 2240
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
P P + + + W + + NG I +Y ++ I+ + +SS Y
Sbjct 2241 PEGVPAPKAHSYSPDSFNVSWTE--PEYPNGVITSYGLYLDGILIH------NSSELSYR 2292
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
+L+ R+ A T +G GP T + T+ +
Sbjct 2293 AYGFAPWSLHSFRVQACTAKGCALGPLVENRTLEAPPE---------------GTVNVFV 2337
Query 639 FCFNKRDLIKKHIWPNVPDP--SKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEI 696
R + P P+ + S + + P N + + + + + +
Sbjct 2338 KTQGSRKAHVRWEAPFRPNGLLTHSVLFTGIFYVDPVGNNYTLLNVTKVMYSGEETNLWV 2397
Query 697 EANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSST 756
+ PF +++ + + M P S+ TS
Sbjct 2398 LIDGLVPFTNYTVQVNISNSQGSLITDPITI-----AMPPGAPDGVLPPRLSSATPTSLQ 2452
Query 757 VQYSTVVHSGYRHQVPSVQVF---SRS-ESTQPLLDSEERP 793
V +ST R+ P + RS +ST L+ P
Sbjct 2453 VVWST----PARNNAPGSPRYQLQMRSGDSTHGFLELFSNP 2489
Score = 137 bits (345), Expect = 2e-31, Method: Composition-based stats.
Identities = 66/439 (15%), Positives = 139/439 (32%), Gaps = 41/439 (9%)
Query 138 EGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV 196
E ++ W + + ++ + + + + + + F N V
Sbjct 2736 EPDAVQVTWKPPLIQNGDILSYEIHMPDPHITLTNVTSAVLSQKVTHL----IPFTNYSV 2791
Query 197 WVEA-ENALGKVTSDHINFDPVYKVKPNPPHNLS-VINSEELSSILKLTWTNPSIKSVII 254
+ A G + + P P N+ + S + ++W PS +
Sbjct 2792 TIVACSGGNGYLGGCTESLPTYVTTHPTVPQNVGPLSVIPLSESYVVISWQPPSKPNGPN 2851
Query 255 LKYNIQYR----------TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
L+Y + R +D + W I + T+ + + L FT Y + +
Sbjct 2852 LRYELLRRKIQQPLASNPPEDLNRWHNIY----SGTQWLYEDKGLSRFTTYEYMLFVHNS 2907
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
G S E + T P + + + + + + W + G++
Sbjct 2908 VGF----TPSREVTVTTLAGLPERGANL-----TASVLNHTAIDVRWAKPTVQDLQGEVE 2958
Query 365 DYEVTLTRWKSHLQNY---TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
Y + + S+ VN+ + N Y ++V N V ++A L CD
Sbjct 2959 YYTLFWSSATSNDSLKILPDVNSHVIGHLKPNTEYWIFISVFNGVHSINSAGLHATTCDG 3018
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
+ + + V WT+P + E+ + + T V ++
Sbjct 3019 EPQGMLPPEVVIINSTAVRVIWTSPSNP-NGVVTEYSIYVNNKLYKTGM-----NVPGSF 3072
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
+ +L+ Y I V + + PS PT + + ++W
Sbjct 3073 ILRDLSPFTIYDIQVEVCTIYACVKSNGTQITTVEDTPSDIPTPTIRGITSRSLQIDW-- 3130
Query 542 LPVDVQNGFIRNYTIFYRT 560
+ NG I Y + ++T
Sbjct 3131 VSPRKPNGIILGYDLLWKT 3149
Score = 133 bits (335), Expect = 3e-30, Method: Composition-based stats.
Identities = 71/461 (15%), Positives = 139/461 (30%), Gaps = 40/461 (9%)
Query 170 ADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN--PPHN 227
+ T D + ++ E + A N+ G+ S + V PP
Sbjct 3448 EETIHTGSVNTYSYTDVNLKPYMTYEYRISAWNSYGRGLSKAVRARTKEDVPQGVSPPTW 3507
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
+ N E+ + L W P + I+ Y + ++ + +
Sbjct 3508 TKIDNLED---TIVLNWRKPIQSNGPIIYYIL---LRNGIERFRGTSLSFSDKE------ 3555
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK--APSFWYKIDPSHTQGYR 345
++PF EY ++++ G S + T + P PS
Sbjct 3556 GIQPFQEYSYQLKACTVAGCAT----SSKVVAATTQGVPESILPPSI-------TALSAV 3604
Query 346 TVQLVWKTLPPFEANGKILDYEVT-LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRN 404
+ L W P ++NG I +Y++ + + H +T Y TLT
Sbjct 3605 ALHLSWSV--PEKSNGVIKEYQIRQVGKGLIHTDTTDRRQHTVTGLQPYTNYSFTLTACT 3662
Query 405 LVG-KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDK 463
G S L V + + W+ P E + ++ +
Sbjct 3663 SAGCTSSEPFLGQTLQAAPEGVWVTPRHIIINSTTVELYWSLP-EKPNGLVSQY-----Q 3716
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG- 522
+ G+ + + NL + Y + G + + + P +
Sbjct 3717 LSRNGNLLFLGGSEEQNFTDKNLEPNSRYTYKLEVKTGGGSSASDDYIVQTPMSTPEEIY 3776
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
P +G + W + + + Y + A +V H L +L
Sbjct 3777 PPYNITVIGPYSIFVAWIPPGILIPEIPV-EYNVLLNDGSVTPLAFSV-GHHQSTLLENL 3834
Query 583 TSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
T T Y +R+ A + TP+ A ++ + V+
Sbjct 3835 TPFTQYEIRIQACQNGSCGVSSRMFVKTPEAAPMDLNSPVL 3875
Score = 131 bits (328), Expect = 2e-29, Method: Composition-based stats.
Identities = 106/614 (17%), Positives = 182/614 (30%), Gaps = 75/614 (12%)
Query 126 PEKPKNL---SCIVNEGKKMRCEWDGGRETHLET-NFTLKSEWATHKFADCKAKRDTPTS 181
P P + +++ WD T+ + N+TL + T S
Sbjct 4529 PSAPSGMEPPKLQARGPQEILVNWDPPVRTNGDIINYTLFIRELFERETKIIHINTTHNS 4588
Query 182 ----CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN-PPHNLSVINSEEL 236
+ F E+ ++A LG +SD PP +L V +
Sbjct 4589 FGMQSYIVNQLKPFHRYEIRIQACTTLGCASSDWTFIQTPEIAPLMQPPPHLEVQMAPGG 4648
Query 237 -SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+ L WT P + +L Y + R P + +SF +L PFTEY
Sbjct 4649 FQPTVSLLWTGPLQPNGKVLYYELYRRQIATQPRKSNPVLIYNGSSTSFIDSELLPFTEY 4708
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPS--KAPSFWYKIDPSHTQGYRTVQLVWKT 353
+++ + GK S T P +AP+F S TQ +
Sbjct 4709 EYQVWAVNSAGK----APSSWTWCRTGPAPPEGLRAPTFHVI---SSTQAVVNIS----- 4756
Query 354 LPPFEANGKILDYEVTLTRWK---SHLQNYTVNATKLTVNLTNDRYLATLTV---RNLVG 407
P + NG + Y + + + L L Y + N
Sbjct 4757 -APGKPNGIVSLYRLFSSSAHGAETVLSEGMATQQTLHGLQAFTNYSIGVEACTCFNCCS 4815
Query 408 KSD-AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
K A + T PA + P + A + W P + Y L++ V
Sbjct 4816 KGPTAELRTHPAPPSGLSSPQIGTLASRTASFRWSPPMFPNGVIHSYELQFHVACPPDSA 4875
Query 467 I----TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+ + + + + + G L Y + V G + E I ++ P
Sbjct 4876 LPCTPSQIETKYTGLGQKASLGGLQPYTTYKLRVVAHNEVGSTASEWISFTTQKELPQYR 4935
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI---FYRTIIGNETAVNVDSSHTEYTL 579
+ + W + NG ++ Y + R G +T + + +
Sbjct 4936 APFSV-DSNLSVVCVNWSDT--FLLNGQLKEYVLTDGGRRVYSGLDTTLYIPRTA----- 4987
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFT----------FTTPKFAQGEIEAIV------- 622
D + ++ TDEG P TTP +G
Sbjct 4988 -----DKTFFFQVICTTDEGSVKTPLIQYDTSTGLGLVLTTPGKKKGSRSKSTEFYSELW 5042
Query 623 VPVCLAFLLTTLLGVLFCF-NKRDLIKKHIW----PNVPDPSKSHIAQWSPHTPPRHNFN 677
V +A L LL + +R + K+ P VP + P H
Sbjct 5043 FIVLMAMLGLILLAIFLSLILQRKIHKEPYIRERPPLVPLQKRMSPLNVYPP-GENHMGL 5101
Query 678 SKDQMYSDGNFTDV 691
+ ++ G +
Sbjct 5102 ADTKIPRSGTPVSI 5115
Score = 128 bits (322), Expect = 1e-28, Method: Composition-based stats.
Identities = 80/540 (15%), Positives = 161/540 (30%), Gaps = 52/540 (10%)
Query 103 CNILTFGQLEQNVYGITIISGLPPEKPKNLS--CIVNEGKKMRCEWDGGRE-THLETNFT 159
C + + + P E P+ + + + W+ ++ + T +
Sbjct 2035 CTLAGCTESSHA-----LNISTPQEAPQEVQPPVAKSLPSSLLLSWNPPKKANGIITQYC 2089
Query 160 LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYK 219
L + D + + F + + A +G S + +Y
Sbjct 2090 L--------YMDGRLIYSGSEENYIVTDLAVFTPHQFLLSACTHVGCTNSS---WVLLYT 2138
Query 220 VKPNPPHNL-SVINSEELSSILKLTWTNPSIKSVIILKYNIQY--RTKDASTWSQIPPED 276
+ PP ++ S + + S + + W P S I+ +Y + T D + WS I +
Sbjct 2139 AQ-LPPEHVDSPVLTVLDSRTIHIQWKQPRKISGILERYVLYMSNHTHDFTIWSVI--YN 2195
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ +Q + P +Y+ ++ G SE + +T ED P P+
Sbjct 2196 STELFQDHMLQYVLPGNKYLIKLGACTGGG----CTVSEASEALTDEDIPEGVPAPK--- 2248
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRY 396
+H+ + + W P NG I Y + L H + + +
Sbjct 2249 --AHSYSPDSFNVSWTE--PEYPNGVITSYGLYLDGILIHNSSELSYRAYGFAPWSL--H 2302
Query 397 LATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP--RESVKKYI 454
+ G + ++ + V V W P + +
Sbjct 2303 SFRVQACTAKGCALGPLVENRTLEAPPEGTVNVFVKTQGSRKAHVRWEAPFRPNGLLTHS 2362
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRT--------YLRGNLAESKCYLITVTPVYADGPGS 506
+ + + P ++ + T L L Y + V + G
Sbjct 2363 VLFTGIFYVDPVGNNYTLLNVTKVMYSGEETNLWVLIDGLVPFTNYTVQVNISNSQGSLI 2422
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET 566
+ I + P R + W + G R Y + R+
Sbjct 2423 TDPITIAMPPGAPDGVLPPRLSSATPTSLQVVWSTPARNNAPGSPR-YQLQMRSGDSTHG 2481
Query 567 AVNVDSSHT---EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
+ + S+ + Y +S L T YM R+ A G F T + G + ++
Sbjct 2482 FLELFSNPSASLSYEVSDLQPYTEYMFRLVASNGFGSAHSSWIPFMTAEDKPGPVVPPIL 2541
Score = 86.8 bits (213), Expect = 8e-16, Method: Composition-based stats.
Identities = 66/446 (15%), Positives = 125/446 (28%), Gaps = 38/446 (9%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIIN-RTASSVTFT 92
+ PVV + K + + + I H T+ +++ + + FT
Sbjct 2728 QPPVVTVLEPDAVQVTWKPPLIQNGDILSYEIHMPDPHITLTNVTSAVLSQKVTHLIPFT 2787
Query 93 DIASLNIQ-LTCNILTFGQLEQNVYGITIISGLPPEKPKN---LSCIVNEGKKMRCEWDG 148
+ + + N G E + P P+N LS I + W
Sbjct 2788 NYSVTIVACSGGNGYLGGCTES----LPTYVTTHPTVPQNVGPLSVIPLSESYVVISWQP 2843
Query 149 -GRETHLETNFTLKSEWATHKFADCKAKRDTPTS--------CTVDYSTVYFVNIEVWVE 199
+ + L A + D F E +
Sbjct 2844 PSKPNGPNLRYELLRRKIQQPLASNPPEDLNRWHNIYSGTQWLYEDKGLSRFTTYEYMLF 2903
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
N++G S + + P ++ S + + + W P+++ L+ +
Sbjct 2904 VHNSVGFTPSREVTVTTLAG---LPERGANLTASVLNHTAIDVRWAKPTVQD---LQGEV 2957
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+Y T S+ + +S + LKP TEY I G S S
Sbjct 2958 EYYTLFWSSATSNDSLKILPDVNSHVIGHLKPNTEYWIFISVFN----GVHSINSAGLHA 3013
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN 379
T + P I V+++W P NG + +Y + +
Sbjct 3014 TTCDGEPQGMLPPEVVI-----INSTAVRVIW--TSPSNPNGVVTEYSIYVNNKLYKTGM 3066
Query 380 YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNML 439
+ L Y + V + + I + + L
Sbjct 3067 NVPGSFILRDLSPFTIYDIQVEVCTIYACVKSNGTQITTVEDTPSDIPTPTIRGITSRSL 3126
Query 440 WVEWTTPRES---VKKYILEWCVLSD 462
++W +PR+ + Y L W
Sbjct 3127 QIDWVSPRKPNGIILGYDLLWKTWYP 3152
Score = 85.3 bits (209), Expect = 2e-15, Method: Composition-based stats.
Identities = 44/212 (21%), Positives = 74/212 (35%), Gaps = 16/212 (8%)
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
L V NL+G S FQ P +++ + + + W+ P +S + L + +
Sbjct 1042 LDVNNLLGCSK--------TPFQQPPPRGQVQS---SSAINLSWSPP-DSPNAHWLTYSL 1089
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
L D T Q ++ L +L Y + G ++ K P
Sbjct 1090 LRDGFEIYTTEDQYPYSIQYF-LDTDLLPYTKYSYYIETTNVHGSTRSVAVTYKTKPGVP 1148
Query 520 SKGPTVR-TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
T+ +G + L W L Q+G I Y + + G + V+ + T T
Sbjct 1149 EGNLTLSYIIPIGSDSVTLTWTTL--SNQSGPIEKYILSCAPLAGGQPCVSYEGHETSAT 1206
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ +L Y + A T G T TT
Sbjct 1207 IWNLVPFAKYDFSVQACTSGGCLHSLPITVTT 1238
Score = 73.4 bits (178), Expect = 9e-12, Method: Composition-based stats.
Identities = 37/192 (19%), Positives = 63/192 (33%), Gaps = 16/192 (8%)
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS--KGPTVRTKKVGK 532
+Y NL Y ++ + G G ++++A K+ P PT +
Sbjct 3455 SVNTYSYTDVNLKPYMTYEYRISAWNSYGRGLSKAVRARTKEDVPQGVSPPTWTKIDNLE 3514
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+ VL W NG I Y I R I ++ S + Y ++
Sbjct 3515 DTIVLNWR--KPIQSNGPII-YYILLRNGIERFRGTSLSFSDK----EGIQPFQEYSYQL 3567
Query 593 AAYTDEGGKDGPEFTFTTPKFAQGEI--EAIVVPVCLAFLLTTLL-----GVLFCFNKRD 645
A T G + T + I +I +A L+ + GV+ + R
Sbjct 3568 KACTVAGCATSSKVVAATTQGVPESILPPSITALSAVALHLSWSVPEKSNGVIKEYQIRQ 3627
Query 646 LIKKHIWPNVPD 657
+ K I + D
Sbjct 3628 VGKGLIHTDTTD 3639
Score = 39.8 bits (91), Expect = 0.14, Method: Composition-based stats.
Identities = 21/121 (17%), Positives = 37/121 (31%), Gaps = 4/121 (3%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
P + P R + + L W P D N Y++ T S +
Sbjct 1054 PFQQPPPRGQVQSSSAINLSWS--PPDSPNAHWLTYSLLRDGFEIYTTEDQYPYSIQYFL 1111
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT-PKFAQGEIEA-IVVPVCLAFLLTTLLG 636
+ L T Y + G T+ T P +G + ++P+ + T
Sbjct 1112 DTDLLPYTKYSYYIETTNVHGSTRSVAVTYKTKPGVPEGNLTLSYIIPIGSDSVTLTWTT 1171
Query 637 V 637
+
Sbjct 1172 L 1172
Score = 36.8 bits (83), Expect = 1.4, Method: Composition-based stats.
Identities = 14/74 (19%), Positives = 25/74 (34%), Gaps = 7/74 (9%)
Query 194 IEVWVEAENALGKVTSDHINFDPVY--KVKPNPPHNLSVINSEELSSILKLTWTNPSIKS 251
E + N++G VTS + + PP + S+ + L W P +
Sbjct 1440 YEFTITLCNSVGCVTSASGAGQTLAAAPAQLRPP-----LVKGINSTTIHLRWFPPEELN 1494
Query 252 VIILKYNIQYRTKD 265
Y ++ R
Sbjct 1495 GPSPIYQLERRESS 1508
>sp|Q98902|L1CAM_TAKRU Neural cell adhesion molecule L1 OS=Takifugu
rubripes OX=31033 GN=l1cam PE=3 SV=1
Length=1277
Score = 195 bits (495), Expect = 8e-50, Method: Composition-based stats.
Identities = 90/601 (15%), Positives = 195/601 (32%), Gaps = 47/601 (8%)
Query 33 PESPVVQLHSNFTAVCVLKEKCM---DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSV 89
P + + + +T V +K + + F + W+++ ++ + T +
Sbjct 442 PPQILTENGNTYTF--VEGQKALLECETFGSPKPKVTWESSSISLLLADPRVNLLTNGGL 499
Query 90 TFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG- 148
+++ + + ++ + N + + P+ L + C +
Sbjct 500 EIANVSHDDEGIYTCLVQGSNISVNAEVEVLNRTVILSPPQALRLQPGKTAIFTCLYVTD 559
Query 149 GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
+ + + + +D K D P + + + + + +
Sbjct 560 PKLSSPLLQWRKNDQKIFESHSDKKYTFDGPGLIISNVEPGDEGVYTCQIITKLDMVEAS 619
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD--A 266
S D +P+PP +L V N++ ++ L WT + IL+Y +++ +D
Sbjct 620 STLTLCD-----RPDPPVHLQVTNAKH--RVVTLNWTPGDDNNSPILEYVVEFEDQDMKE 672
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
+ W ++ + L P+ Y FR+ + + GK S S+ T D P
Sbjct 673 NGWEELKRVAADKKHVNLP---LWPYMSYRFRVIAINDQGKSDPSKLSD--LYKTPADAP 727
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK 386
P S + T+ + W+ + NG Y V R ++ T
Sbjct 728 DSNPEDVR----SESTDPDTLVITWEEMDKRNFNGPDFKYLVMWRRVVGSGPDWHEEYTI 783
Query 387 LTVNLTND-----RYLATLTVRNLVGKSDAA--VLTIPACDFQATHPVMDLKAFPKDNML 439
+ D + + N G ++ D P+ +
Sbjct 784 APPFIVTDVQNFSAFEIKVQAVNKKGLGPEPDPIIGYSGEDVPLEAPLNLGVLLENSTTI 843
Query 440 WVEWTTP-RESVKKYILEWCVL--------SDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
V W+ +E+V+ ++L + + S + G NL
Sbjct 844 RVTWSAVDKETVRGHLLGYKIYLTWGHHRNSRAQEPENIVMVQTGANEEKKSITNLRPYC 903
Query 491 CYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y + ++ + G G ++ + P +++ ++E L W P NG
Sbjct 904 HYDLAISAFNSKGEGPLSEKTSFMTPEGVPGPPMSMQMTSPSESEITLHW--TPPSKPNG 961
Query 550 FIRNYTIFYRTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ Y++ YR + ++ + V T TL L + Y + A T G E
Sbjct 962 ILLGYSLQYRKMQSDDNPLQVVDIASPEITHLTLKGLDRHSHYQFLLMARTAAGKGLSIE 1021
Query 606 F 606
Sbjct 1022 I 1022
Score = 168 bits (426), Expect = 2e-41, Method: Composition-based stats.
Identities = 117/704 (17%), Positives = 227/704 (32%), Gaps = 76/704 (11%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P++ +Q C+ + +++ + W+ N I +
Sbjct 539 PQALRLQPGKTAIFTCLY----VTDPKLSSPLLQWRKNDQKIFESHSDKKYTFDGPGLII 594
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRET 152
+ +L+ T+ P+ P +L + + + W G +
Sbjct 595 SNVEPGDEGVYTCQIITKLDMVEASSTLTLCDRPDPPVHLQVTNAKHRVVTLNWTPGDDN 654
Query 153 HLE-TNFTLKSEWA-THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD 210
+ + ++ E + + KR V+ +++ V A N GK SD
Sbjct 655 NSPILEYVVEFEDQDMKENGWEELKRVAADKKHVNLPLWPYMSYRFRVIAINDQGK--SD 712
Query 211 HINFDPVYKVKPNPP-HNLSVINSEEL-SSILKLTWT--NPSIKSVIILKYNIQYRTK-- 264
+YK + P N + SE L +TW + + KY + +R
Sbjct 713 PSKLSDLYKTPADAPDSNPEDVRSESTDPDTLVITWEEMDKRNFNGPDFKYLVMWRRVVG 772
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
W + F V D++ F+ + +++ + + G G D G + ED
Sbjct 773 SGPDWHEEYTI-----APPFIVTDVQNFSAFEIKVQAVNKKGLGPEPD---PIIGYSGED 824
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN----- 379
P +AP + + T T+++ W + G +L Y++ LT W H +
Sbjct 825 VPLEAPLNLGVLLENST----TIRVTWSAVDKETVRGHLLGYKIYLT-WGHHRNSRAQEP 879
Query 380 ---------YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
+T Y ++ N G+ + T P M +
Sbjct 880 ENIVMVQTGANEEKKSITNLRPYCHYDLAISAFNSKGEGPLSEKTSFMTPEGVPGPPMSM 939
Query 431 K-AFPKDNMLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
+ P ++ + + WT P + + Y L++ + + + L+G L
Sbjct 940 QMTSPSESEITLHWTPPSKPNGILLGYSLQYRKMQSDDNPLQVVDIASPEITHLTLKG-L 998
Query 487 AESKCYLITVTPVYADGPGSPESIKA-YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
Y + A G G I + P ++ ++ L W+
Sbjct 999 DRHSHYQFLLMARTAAGKGLSIEILGATTLEGLPPANISLSAEER---SVNLSWEARKRH 1055
Query 546 VQNGFIRNYTIFYRTIIGNETAVN--VDSSHTEYTLSSLTSDTLYMVRMAAYTD-----E 598
GF +Y T G + V+SS + L LT + Y + + E
Sbjct 1056 RTVGFQIHYFSKNGTKNGGKWKKTEMVNSSLQFFQLQGLTPGSHYRLLFTYKNNTFWETE 1115
Query 599 GGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDP 658
G T P FA + + V A +L L+ ++ CF KR
Sbjct 1116 IQTKGTSVTEVQPSFAT---QGWFIGVVSAVVLLLLVLLILCFIKR-------------- 1158
Query 659 SKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKK 702
S ++S +S+ + D F + +E + +K+
Sbjct 1159 --SKGGKYSVKDKEDGPMDSEARPMKDETFGEYRSLESDLEEKR 1200
Score = 140 bits (353), Expect = 1e-32, Method: Composition-based stats.
Identities = 105/636 (17%), Positives = 191/636 (30%), Gaps = 108/636 (17%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPK---EQYTIINRTASSV 89
P S + C + + I W N + E + + S +
Sbjct 355 PVSQLYAPGETVKLDC-------QADGIPSPTITWTVNGVPLSATSLEPRRSLTESGSLI 407
Query 90 TFTDIASLNIQLTCNILTFGQL---EQNVYGITIISGLPPEKPKN--------------L 132
I C NVY I + PP+ L
Sbjct 408 LKDVIFGDTAIYQCQASNKHGTILANTNVYVIEL----PPQILTENGNTYTFVEGQKALL 463
Query 133 SCIVNEGKKMRCEWDGGRETHL--ETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY 190
C K + W+ + L + L + + A+ + +C V S +
Sbjct 464 ECETFGSPKPKVTWESSSISLLLADPRVNLLTN-GGLEIANVSHDDEGIYTCLVQGSNI- 521
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN-SEELSSILKLTWTNPSI 249
++ VE N V +PP L + + + L +T +P +
Sbjct 522 --SVNAEVEVLNR---------------TVILSPPQALRLQPGKTAIFTCLYVT--DPKL 562
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE--YVFRIRCMKEDGK 307
S + +Q+R D + + + +++P E Y +I
Sbjct 563 SSPL-----LQWRKNDQKIFESHSDKKYTFDGPGLIISNVEPGDEGVYTCQIITKL---- 613
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
D E +S +T DRP +R V L W P + N IL+Y
Sbjct 614 ----DMVEASSTLTLCDRPDPPVHL-----QVTNAKHRVVTLNW--TPGDDNNSPILEYV 662
Query 368 VTLT-------RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI---P 417
V W+ + Y + N GKSD + L+
Sbjct 663 VEFEDQDMKENGWEELKRVAADKKHVNLPLWPYMSYRFRVIAINDQGKSDPSKLSDLYKT 722
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK-----YILEWCVLSDKAPCITDWQQ 472
D ++P + L + W + Y++ W + P DW +
Sbjct 723 PADAPDSNPEDVRSESTDPDTLVITWEEMDKRNFNGPDFKYLVMWRRVVGSGP---DWHE 779
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKV 530
E T+ ++ ++ + I V V G G P+ I Y + P + P +
Sbjct 780 EY-TIAPPFIVTDVQNFSAFEIKVQAVNKKGLGPEPDPIIGYSGEDVPLEAPLNLGVLLE 838
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA---------VNVDSSHTEYTLSS 581
+ W + + G + Y I+ + V ++ + ++++
Sbjct 839 NSTTIRVTWSAVDKETVRGHLLGYKIYLTWGHHRNSRAQEPENIVMVQTGANEEKKSITN 898
Query 582 LTSDTLYMVRMAAYTDEGGKDGPEFT-FTTPKFAQG 616
L Y + ++A+ +G E T F TP+ G
Sbjct 899 LRPYCHYDLAISAFNSKGEGPLSEKTSFMTPEGVPG 934
>sp|Q28235|PRLR_CEREL Prolactin receptor OS=Cervus elaphus OX=9860
GN=PRLR PE=2 SV=1
Length=581
Score = 188 bits (478), Expect = 1e-49, Method: Composition-based stats.
Identities = 58/223 (26%), Positives = 97/223 (43%), Gaps = 15/223 (7%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHK-FADCK-AKRDTPTSC 182
PP KPK + C + C W+ G + L TN+TL +C K P +C
Sbjct 27 PPGKPKIIKCRSPGKETFTCWWEPGSDGGLPTNYTLTYHKEGETLIHECPDYKTGGPNTC 86
Query 183 TVDYSTVYFVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV--INSEELSSI 239
+ V A N +G +SD + D Y V+P PP NL++ + E+
Sbjct 87 YFSKKHTSIWKIYVITVNAINQMGVSSSDPLYVDVTYIVEPEPPANLTLELKHPEDRKPY 146
Query 240 LKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
L + W P++ V +++Y I+ + + A+ W A+ ++ + L P +Y
Sbjct 147 LWIKWFPPTLTDVKSGWFMIQYEIRLKPETAADWEI----HFAAKQTQLKIFSLYPGQKY 202
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+ ++RC + GYWS+WS E+S D P + W +
Sbjct 203 LVQVRCKPD--HGYWSEWSPESSIQIPNDFPVNDTTVWIFVAV 243
Score = 61.4 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 64/418 (15%), Positives = 117/418 (28%), Gaps = 34/418 (8%)
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPR--ESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
P + P W Y L + + + G
Sbjct 25 QSPPGKPKIIKCRSPGKETFTCWWEPGSDGGLPTNYTLTYHKEGETLIHECPDYKTGGPN 84
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-----TVRTKKVGK 532
+ + + + K Y+ITV + G S + + + + P ++ + K
Sbjct 85 TCYFSKKHTSIWKIYVITVNAINQMGVSSSDPLYVDVTYIVEPEPPANLTLELKHPEDRK 144
Query 533 NEAVLEWDQLPVDVQNG--FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMV 590
++W + F+ Y I + + ++ + T+ + SL Y+V
Sbjct 145 PYLWIKWFPPTLTDVKSGWFMIQYEIRLKPETAADWEIHFAAKQTQLKIFSLYPGQKYLV 204
Query 591 RMAAYTDEGGKD--GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIK 648
++ D G PE + P + + V + + L+ V K +
Sbjct 205 QVRCKPDHGYWSEWSPESSIQIPNDFPVNDTTVWIFVAVLSAVICLIMVWAVALKGYSMM 264
Query 649 KHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDL 708
I P VP P I + H + + +F S E E +
Sbjct 265 TCILPPVPGP---KIKGFDIHLLEKGKSEELLRALESQDFPPTSDCEDL------LMEFI 315
Query 709 KSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYR 768
+ D ++ + G M S S +S +S
Sbjct 316 EVDDSEDQQLMPRPSKEHMEQGVKPMHMDPDSDSGRGSCDSPS------LFSEKCDEPQA 369
Query 769 HQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSP 826
H F E + L + E LQ D I YF N + + P
Sbjct 370 H----PFKFYTPEDPEKLENPETNLTCLQAPQSTSREDKI----PYFHANGPKSSTWP 419
Score = 46.0 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 31/191 (16%), Positives = 54/191 (28%), Gaps = 15/191 (8%)
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLP-PFEANGKILDYEVTLTRWKSHLQNYTVNATKLT 388
P KI + G T W+ L Y +Y
Sbjct 27 PPGKPKIIKCRSPGKETFTCWWEPGSDGGLPTNYTLTYHKEGETLIHECPDYKTGGPNTC 86
Query 389 VNLTN-----DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF-----PKDNM 438
Y+ T+ N +G S + L + P +L +
Sbjct 87 YFSKKHTSIWKIYVITVNAINQMGVSSSDPLYVDVTYIVEPEPPANLTLELKHPEDRKPY 146
Query 439 LWVEWTTPRESVKK---YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLIT 495
LW++W P + K +++++ + K DW+ +L + YL+
Sbjct 147 LWIKWFPPTLTDVKSGWFMIQYEIRL-KPETAADWEIHFAAKQTQLKIFSLYPGQKYLVQ 205
Query 496 VTPVYADGPGS 506
V G S
Sbjct 206 VRCKPDHGYWS 216
>sp|Q6JTA8|PRLR_PIG Prolactin receptor OS=Sus scrofa OX=9823 GN=PRLR
PE=2 SV=2
Length=625
Score = 189 bits (480), Expect = 2e-49, Method: Composition-based stats.
Identities = 60/221 (27%), Positives = 96/221 (43%), Gaps = 15/221 (7%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFA-DCK-AKRDTPTSC 182
PP KP+ C E + C W G + L TN+TL F +C K P SC
Sbjct 27 PPGKPEIFKCRSPEKETFTCWWKPGADGGLPTNYTLTYHKEGETFTHECPDYKTGGPNSC 86
Query 183 TVDYSTVYFVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEELSSI 239
+ + V A N +G +SD D Y V+P+PP NL+ + E+
Sbjct 87 YFNKKHTSIWTIYIITVNATNQMGSSSSDPRYVDVTYIVEPDPPVNLTLELKKPEDQKPY 146
Query 240 LKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
L + W P++ V + L+Y I+ + + + W A ++ F + L P +Y
Sbjct 147 LWIKWLPPTLVDVRSGWLTLQYEIRLQPEKTAEWET----HFAGQQTQFKILSLYPGQKY 202
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ ++RC + G+WS+WS E+S D K + W +
Sbjct 203 LVQVRCKPD--HGFWSEWSPESSIQIPNDFSMKDTTMWIFV 241
Score = 53.3 bits (126), Expect = 8e-06, Method: Composition-based stats.
Identities = 54/298 (18%), Positives = 95/298 (32%), Gaps = 24/298 (8%)
Query 490 KCYLITVTPVYADGPGSPES---IKAYLKQAPPSKGPTVRTKKVGKNE--AVLEWDQLP- 543
Y+ITV G S + Y+ + P T+ KK + ++W
Sbjct 97 TIYIITVNATNQMGSSSSDPRYVDVTYIVEPDPPVNLTLELKKPEDQKPYLWIKWLPPTL 156
Query 544 VDVQNGFIR-NYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG--G 600
VDV++G++ Y I + E + T++ + SL Y+V++ D G
Sbjct 157 VDVRSGWLTLQYEIRLQPEKTAEWETHFAGQQTQFKILSLYPGQKYLVQVRCKPDHGFWS 216
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
+ PE + P + + + V + + L+ + K + I P VP P
Sbjct 217 EWSPESSIQIPNDFSMKDTTMWIFVAILSAVVCLIMIWAVALKGYSMVACILPPVPGP-- 274
Query 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSV-----VEIEANDKKPFPEDLKSLDLFK 715
I + H + +F S VE D + + +
Sbjct 275 -KIKGFDTHLLEKGKSEELLSALGCQDFPPTSDCEDLLVEFLEVDDSEDQQLMPAHSKEH 333
Query 716 KEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPS 773
+ H S S PS+ S +E N H+ + P
Sbjct 334 PSQGRKPTHLDPDSDSGRGSCDSPSLLSEKCDEPRANPPK-------FHTPEGIEKPG 384
Score = 46.0 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 26/182 (14%), Positives = 48/182 (26%), Gaps = 15/182 (8%)
Query 330 PSFWYKIDPSHTQGYRTVQLVWKT-LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLT 388
P +I + T WK L Y + +Y
Sbjct 27 PPGKPEIFKCRSPEKETFTCWWKPGADGGLPTNYTLTYHKEGETFTHECPDYKTGGPNSC 86
Query 389 VNLTN-----DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM----- 438
Y+ T+ N +G S + + P ++L K
Sbjct 87 YFNKKHTSIWTIYIITVNATNQMGSSSSDPRYVDVTYIVEPDPPVNLTLELKKPEDQKPY 146
Query 439 LWVEWTTPRE---SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLIT 495
LW++W P L++ + +W+ + +L + YL+
Sbjct 147 LWIKWLPPTLVDVRSGWLTLQYEIRLQPE-KTAEWETHFAGQQTQFKILSLYPGQKYLVQ 205
Query 496 VT 497
V
Sbjct 206 VR 207
>sp|Q9BMN8|LAR_CAEEL Tyrosine-protein phosphatase Lar-like OS=Caenorhabditis
elegans OX=6239 GN=ptp-3 PE=1 SV=1
Length=2200
Score = 194 bits (493), Expect = 2e-49, Method: Composition-based stats.
Identities = 103/629 (16%), Positives = 182/629 (29%), Gaps = 69/629 (11%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
VV + N CV + WK + + T + +T T + S
Sbjct 261 VVGVGGNINLTCV-------AVGYPMPRVFWKKTDLMVLDDPSTAPIG-KNVLTLTHVES 312
Query 97 LNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLET 156
+ G +E I LPP P N+ + + W +
Sbjct 313 TENFTCVAVSALGNIEATT--TVIAKELPP-PPVNIVVSSVTSESVVITWKPPKYNEAIN 369
Query 157 NFTLKSEWATHKFADCKAKR-DTPTSCTVDYSTVYFVNIEVWVEAENALGK-VTSDHINF 214
+ + + + K +T + V V F E V + +G + S +
Sbjct 370 KYVVNYRLKYSEGRSSRGKTMETLENSLVIDGLVAFQTYEFTVRSAGPVGVGLESLPVEA 429
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW--SQI 272
P + + S + + W + +I Y + Y T D T +
Sbjct 430 QTKPSKPATAPVSPQARSLNRDS--ILVKWGPCEQPNGLITGYKV-YYTNDLVTTPIREW 486
Query 273 PPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF 332
D S T+ L+P + Y R+ +G S S + T + P + P
Sbjct 487 KQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGD---SPLSTLVTVATRQGIPGQPPML 543
Query 333 WYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ---NYTVNATKLTV 389
K R +QL W + ++ Y V + +T
Sbjct 544 TVKA-----LDSRRMQLTWD---KPLYSSPVVGYTVRYNTSDGEKELTLTSPHEKHVVTG 595
Query 390 NLTNDRYLATLTVRNLVGKSDAAVLTIP--ACDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
+ Y + + G+ + I + P + A + + W P
Sbjct 596 LHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPE 655
Query 448 ESVKKYI---------------------LEWCVLSDKAPCITD-WQQEDGTVHRTYLRGN 485
+ + +E+ D + D + +Y+ +
Sbjct 656 QKKLNGVLTAYRINYFRLEDSKTANLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSD 715
Query 486 LAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
L Y ITV DG G SI+ + PS + L WD
Sbjct 716 LLPYSSYEITVAASTMDGYGPESSIRVVKTLEDVPSAPRNFNAELTSATSVKLTWDA--P 773
Query 545 DVQNGFIRNYTIFY------RTIIGNETAVNV----DSSHTEYTLSSLTSDTLYMVRMAA 594
NG + Y ++ ++ + + DSS + L SL +T Y R+ A
Sbjct 774 AAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNA 833
Query 595 YTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
+ G + E + E IV
Sbjct 834 FNRNGDGEFSERKSIITQGIPPEAPEIVS 862
Score = 159 bits (402), Expect = 3e-38, Method: Composition-based stats.
Identities = 107/596 (18%), Positives = 184/596 (31%), Gaps = 75/596 (13%)
Query 64 YIVWKTNHFTIPKEQYTIINRT---ASSVTFTDIASLNIQLTCN--------ILTFGQLE 112
+ W ++ P YT+ T +T T ++ + + +
Sbjct 554 QLTWDKPLYSSPVVGYTVRYNTSDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRG 613
Query 113 QNVYGITIIS----GLPPEKPKNLSCIVNEGKKMRCEWDG-------GRETHLETNFTLK 161
Q + +IS +P P +S K + W G G T N+
Sbjct 614 QGEFTEPMISKTIASIPLSSPTIVSAAATSSKSVEIRWKGPEQKKLNGVLTAYRINYFRL 673
Query 162 SEWATHKFADCKAKRDTPTSCTVD----------------YSTVYFVNIEVWVEAENALG 205
+ T + D S + + + + E+ V A G
Sbjct 674 EDSKTANLESVEYDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDG 733
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY-RTK 264
I + P+ P N + + ++ +KLTW P+ + +L Y + R
Sbjct 734 YGPESSIRVVKTLEDVPSAPRNFNAELT--SATSVKLTWDAPAAANGALLGYYVYLDRMV 791
Query 265 DASTW-----SQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ + S++ F + L P TEY FR+ +G G + SE S
Sbjct 792 NGEPVVEKGSKKRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEF---SERKSI 848
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG-KILDYEVTLT------- 371
IT + P +AP + + ++ WK +P + N I Y + L
Sbjct 849 IT-QGIPPEAPEI-VSVSLDRDEPPVVARIEWK-MPKMKPNETPIEKYNLWLRAQGYPDS 905
Query 372 RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
K+ + T +T ++ Y L N G+S A TI +D++
Sbjct 906 YVKAKTVDGTDLSTTISGLWMGVVYDVLLAAENREGRSQNATETIATPVGSPDGEPIDVQ 965
Query 432 AFPKDNMLWVEWTTPRESVKKY-ILEWCVLSD--KAPCITDWQQEDGTVHRTYLRGNLAE 488
+ V W P E + I + + A Q + N+
Sbjct 966 YEVMKGKIVVSWRPPSEEKRNGNITSYKAILSAMDATADRYEQPVPAPSTSSTFEVNVRR 1025
Query 489 SKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP--TVRTKKVGKNEAVLEWDQLPVDV 546
YL V G G + GP VR + + AV++WD
Sbjct 1026 --AYLFKVAAATMKGIGPYSPVLTINPDPAALVGPPTNVRVEATSNSTAVVQWD-FESQK 1082
Query 547 QNGFIRNYT--IFYRTIIGNETAVNVDSSHTE-----YTLSSLTSDTLYMVRMAAY 595
+ F+ Y R + V S E +S L + Y + A
Sbjct 1083 ADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPKRFAVVSDLNAHKPYAFCVLAV 1138
Score = 141 bits (354), Expect = 1e-32, Method: Composition-based stats.
Identities = 103/717 (14%), Positives = 203/717 (28%), Gaps = 96/717 (13%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P P+N + + ++ WD + + + + +
Sbjct 749 VPSAPRNFNAELTSATSVKLTWDAPAAANGALLGYYVYLDRMVNGEPVVEKGSKKRIVMI 808
Query 184 VDYSTVYF--------VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
D S YF + A N G + P P +SV +
Sbjct 809 RDSSKRYFELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLDRD 868
Query 236 LSSIL-KLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
++ ++ W P + I KYN+ R + S + + T S T+ L
Sbjct 869 EPPVVARIEWKMPKMKPNETPIEKYNLWLRAQGYPD-SYVKAKTVDGTDLSTTISGLWMG 927
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
Y + +G+ S + E + T P P ID + + + W+
Sbjct 928 VVYDVLLAAENREGR---SQNATE-TIATPVGSPDGEP-----IDVQYEVMKGKIVVSWR 978
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNY------TVNATKLTVNLTNDRYLATLTVRNLV 406
+ NG I Y+ L+ + Y ++ VN+ YL + +
Sbjct 979 PPSEEKRNGNITSYKAILSAMDATADRYEQPVPAPSTSSTFEVNVRR-AYLFKVAAATMK 1037
Query 407 GKSD-AAVLTIPACDFQATHPVMDLKAFPKDNML-WVEWTTPRESVKKYILEWCVLSDKA 464
G + VLTI P +++ N V+W + +++++
Sbjct 1038 GIGPYSPVLTINPDPAALVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNR 1097
Query 465 PCITDWQQED------GTVHRTYLRGNLAESKCYLITVTPVYA----------------- 501
W+Q R + +L K Y V V
Sbjct 1098 MDTEKWKQLPVVSIDKENPKRFAVVSDLNAHKPYAFCVLAVKNNLTLNEQFNKVRVTNYM 1157
Query 502 ---DGPGSPESIKAYLKQAPPS-KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN---- 553
G L+ P+ +R N L W+ ++ +
Sbjct 1158 TNFQRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRNVGFYVNHTGRK 1217
Query 554 -YT---IFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF--- 606
Y + +T+ +VD H EY ++L +Y + + T G
Sbjct 1218 DYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHMMYTIHVGVRT---LPPGARKYWP 1274
Query 607 ----TFTTPKFAQG-----EIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPD 657
T T P +++ + T + I +
Sbjct 1275 QEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATEEYGPISHYWI-------ILV 1327
Query 658 PSKSH---IAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLF 714
P+ + P + + Q+ + + ++ +A++ +D +S
Sbjct 1328 PANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASE---VGDDSQSASYH 1384
Query 715 KKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQV 771
KEK G ++ +S+ R + N + Y + H +
Sbjct 1385 PKEKRARRATVPGAYVTARLSADR--VKQQYRNNQPFIVGDSQLYDGFTNYPLEHNL 1439
>sp|P05710|PRLR_RAT Prolactin receptor OS=Rattus norvegicus OX=10116
GN=Prlr PE=1 SV=2
Length=610
Score = 188 bits (477), Expect = 3e-49, Method: Composition-based stats.
Identities = 64/232 (28%), Positives = 103/232 (44%), Gaps = 16/232 (7%)
Query 115 VYGITIISGL-PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKF-ADC 172
V I+++ G PP KP+ C + + C W+ G + L TN++L K +C
Sbjct 11 VLNISLLKGQSPPGKPEIHKCRSPDKETFTCWWNPGTDGGLPTNYSLTYSKEGEKTTYEC 70
Query 173 K-AKRDTPTSCTVDYSTVYFVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS- 229
K P SC + V A N +G +SD + D Y V+P PP NL+
Sbjct 71 PDYKTSGPNSCFFSKQYTSIWKIYIITVNATNQMGSSSSDPLYVDVTYIVEPEPPRNLTL 130
Query 230 -VINSEELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
V ++ + L + W+ P+I V ++Y I+ + ++A W ++ F
Sbjct 131 EVKQLKDKKTYLWVKWSPPTITDVKTGWFTMEYEIRLKPEEAEEWEI----HFTGHQTQF 186
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
V DL P +Y+ + RC + GYWS WS+E+S D K + W +
Sbjct 187 KVFDLYPGQKYLVQTRCKPD--HGYWSRWSQESSVEMPNDFTLKDTTVWIIV 236
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 48/287 (17%), Positives = 84/287 (29%), Gaps = 14/287 (5%)
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTT--PRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
P + P W Y L + +K + G
Sbjct 20 QSPPGKPEIHKCRSPDKETFTCWWNPGTDGGLPTNYSLTYSKEGEKTTYECPDYKTSGPN 79
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-----TVRTKKVGK 532
+ + + K Y+ITV G S + + + + P V+ K K
Sbjct 80 SCFFSKQYTSIWKIYIITVNATNQMGSSSSDPLYVDVTYIVEPEPPRNLTLEVKQLKDKK 139
Query 533 NEAVLEWDQLP-VDVQNG-FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMV 590
++W DV+ G F Y I + E ++ T++ + L Y+V
Sbjct 140 TYLWVKWSPPTITDVKTGWFTMEYEIRLKPEEAEEWEIHFTGHQTQFKVFDLYPGQKYLV 199
Query 591 RMAAYTDEGGKD--GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIK 648
+ D G E + P + + + V + + L+ V K +
Sbjct 200 QTRCKPDHGYWSRWSQESSVEMPNDFTLKDTTVWIIVAILSAVICLIMVWAVALKGYSMM 259
Query 649 KHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVE 695
I+P VP P I + H + +F S E
Sbjct 260 TCIFPPVPGP---KIKGFDTHLLEKGKSEELLSALGCQDFPPTSDCE 303
Score = 50.6 bits (119), Expect = 6e-05, Method: Composition-based stats.
Identities = 31/220 (14%), Positives = 59/220 (27%), Gaps = 28/220 (13%)
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ------NYTVN 383
P +I + T W P G +Y +T ++ +
Sbjct 22 PPGKPEIHKCRSPDKETFTCWW---NPGTDGGLPTNYSLTYSKEGEKTTYECPDYKTSGP 78
Query 384 ATKLTVNLTNDR---YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF-----PK 435
+ Y+ T+ N +G S + L + P +L K
Sbjct 79 NSCFFSKQYTSIWKIYIITVNATNQMGSSSSDPLYVDVTYIVEPEPPRNLTLEVKQLKDK 138
Query 436 DNMLWVEWTTPRESVKKYILEWCVLSD----KAPCITDWQQEDGTVHRTYLRGNLAESKC 491
LWV+W+ P + W + K +W+ + +L +
Sbjct 139 KTYLWVKWSPPT--ITDVKTGWFTMEYEIRLKPEEAEEWEIHFTGHQTQFKVFDLYPGQK 196
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
YL+ G S + +++ K
Sbjct 197 YLVQTRCKPDHGYWS-----RWSQESSVEMPNDFTLKDTT 231
>sp|Q8AXZ4|CNT1A_DANRE Contactin-1a OS=Danio rerio OX=7955 GN=cntn1a
PE=2 SV=1
Length=1032
Score = 193 bits (489), Expect = 3e-49, Method: Composition-based stats.
Identities = 72/385 (19%), Positives = 126/385 (33%), Gaps = 27/385 (7%)
Query 234 EELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS-TWS--QIPPEDTASTRSSFTVQDLK 290
E S +++ W++ + I +Y +Q R A W P + TV +L
Sbjct 627 EVTSDSVRVLWSHGTDNLSPISRYTVQLRESAAQQDWRDAATSPVNVEGNAEMATVVNLL 686
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
P+TEY FR+ G G S+ S + + T E RP APS R + +
Sbjct 687 PWTEYEFRVIATNTLGTGPPSEPSPKTT--TREARPIVAPSD----IGGGGGTSRELTIT 740
Query 351 WKTLPPFEANGKILDYEVTLTRWKS-HLQNYTVNATKLTVNLTND-------RYLATLTV 402
W + G Y + TV + + D R+ +
Sbjct 741 WTPVQSQYYYGSNFGYIIAFKPHNDPEWLRVTVTDPEAQKYVHKDPKIPPSTRFEVKMKA 800
Query 403 RNLVGKSDAAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTPR-ESVKKYILEWCV 459
N G+ + A D A P++ V W + +V++Y + +
Sbjct 801 FNSQGEGPFSNSAFIYSAQDVPAEAPIITEARALSATEAIVIWVPVQLPTVERYQVRYWR 860
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA-YLKQAP 518
S + + T L N+ YL+ V G G Y K++P
Sbjct 861 ESVENEASAQRVLVSSRENHTRL-DNMKPDSHYLVEVRACNGAGYGPASQRNRIYTKKSP 919
Query 519 PSKGPTV--RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
PS+ P + + W+++ + Y + YR + +
Sbjct 920 PSRPPKIISTKMHYSGTSINIAWEKVESLNNESTVAGYKVLYRQHGQPSGTL-YTTEKQS 978
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGK 601
L Y+V + A+++ G
Sbjct 979 IDLP--MRRGEYLVEVRAHSEGGDG 1001
Score = 108 bits (270), Expect = 1e-22, Method: Composition-based stats.
Identities = 64/402 (16%), Positives = 123/402 (31%), Gaps = 47/402 (12%)
Query 138 EGKKMRCEWDGGRETHLE-TNFT--LKSEWATHKFAD---CKAKRDTPTSCTVDYSTVYF 191
+R W G + + +T L+ A + D + + + +
Sbjct 629 TSDSVRVLWSHGTDNLSPISRYTVQLRESAAQQDWRDAATSPVNVEGNAEMATVVNLLPW 688
Query 192 VNIEVWVEAENALGKV-TSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTN--P 247
E V A N LG S+ + +P P ++ S L +TWT
Sbjct 689 TEYEFRVIATNTLGTGPPSEPSPKTTTREARPIVAPSDIG--GGGGTSRELTITWTPVQS 746
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
Y I ++ + W ++ D + + + P T + +++ G+
Sbjct 747 QYYYGSNFGYIIAFKPHNDPEWLRVTVTDPEAQKYVHKDPKIPPSTRFEVKMKAFNSQGE 806
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
G + S A + +D P++AP I + ++W + + Y+
Sbjct 807 GPF---SNSAFIYSAQDVPAEAP----IITEARALSATEAIVIWVPVQLPT----VERYQ 855
Query 368 VTLTRWKSHLQNYT--------VNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPA 418
V R + N T+L + YL + N G A+ I
Sbjct 856 VRYWRESVENEASAQRVLVSSRENHTRLDNMKPDSHYLVEVRACNGAGYGPASQRNRIYT 915
Query 419 CDFQATHPV--MDLKAFPKDNMLWVEWT-----TPRESVKKYILEWCVLSDKAPCITDWQ 471
+ P + K + + W +V Y + + P T +
Sbjct 916 KKSPPSRPPKIISTKMHYSGTSINIAWEKVESLNNESTVAGYKVLYRQHGQ--PSGTLYT 973
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
E ++ RG YL+ V G G+ ++
Sbjct 974 TEKQSIDLPMRRGE------YLVEVRAHSEGGDGAVAQVRIT 1009
Score = 59.1 bits (141), Expect = 2e-07, Method: Composition-based stats.
Identities = 40/217 (18%), Positives = 67/217 (31%), Gaps = 29/217 (13%)
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT--IIGNETA-----VNVDSSHTEYTLSS 581
+V + + W I YT+ R + VNV+ + T+ +
Sbjct 627 EVTSDSVRVLWSHG--TDNLSPISRYTVQLRESAAQQDWRDAATSPVNVEGNAEMATVVN 684
Query 582 LTSDTLYMVRMAAYTDEGGKD----GPEFTFT--TPKFAQGEIEAIVV----------PV 625
L T Y R+ A G P+ T P A +I PV
Sbjct 685 LLPWTEYEFRVIATNTLGTGPPSEPSPKTTTREARPIVAPSDIGGGGGTSRELTITWTPV 744
Query 626 CLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMY-- 683
+ + G + F K + + V DP P PP F K + +
Sbjct 745 QSQYYYGSNFGYIIAF-KPHNDPEWLRVTVTDPEAQKYVHKDPKIPPSTRFEVKMKAFNS 803
Query 684 -SDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKI 719
+G F++ + + + P ++ L E I
Sbjct 804 QGEGPFSNSAFIYSAQDVPAEAPIITEARALSATEAI 840
>sp|Q91094|PRLR_MELGA Prolactin receptor OS=Meleagris gallopavo
OX=9103 GN=PRLR PE=2 SV=1
Length=831
Score = 190 bits (483), Expect = 5e-49, Method: Composition-based stats.
Identities = 86/427 (20%), Positives = 148/427 (35%), Gaps = 45/427 (11%)
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH 153
I+S+ I L + T G Q+ P KPK + C E + C W G +
Sbjct 6 ISSVQIILLLPLTTVGLTSQSF----------PGKPKIIRCRSLEKETFSCWWKPGSDGG 55
Query 154 LETNFTLKSEWAT-HKFADCK-AKRDTPTSCTVDYSTV-YFVNIEVWVEAENALGKVTSD 210
L TN+TL + K +C + P SC + + + + V A N +G +SD
Sbjct 56 LPTNYTLFYSKDSEEKIYECPDYRTSGPNSCYFNRNYTNSWTTYNITVTATNEIGSNSSD 115
Query 211 HINFDPVYKVKPNPPHNLSVINSEELS-SILKLTWTNP---SIKSVIILKYNIQYRTKDA 266
D V+P P NL++ + L W+ P S + Y ++ + ++
Sbjct 116 PQYVDVTSIVQPGSPVNLTLETQRYANIMYLWAKWSPPLLADASSNHLYHYELRLKPEEK 175
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
W +P ++ + L YV ++RCM G WS+WS E +
Sbjct 176 EEWETVP----VGVQTQCKINRLNAGMRYVVQVRCM--LDPGEWSEWSSERRILISGGL- 228
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL-------QN 379
+P I + T WK P G +Y + ++ +
Sbjct 229 --SPPEKPTITKCRSPEKETFTCWWK---PGLDGGHPTNYTLLYSKEGEEQVYECPDYRT 283
Query 380 YTVNATKLTVNLTN--DRYLATLTVRNLVGKSDA-----AVLTIPACDFQATHPVMDLKA 432
N+ T+ Y T+ N +G + + V I D A + K
Sbjct 284 AGPNSCYFDKKHTSFWTVYNITVKATNEMGSNSSDPHYVDVTYIVQPDPPANVTLELKKP 343
Query 433 FPKDNMLWVEWTTPRESVK--KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
+ L + W+ P + ++ L K +W+ Y +L K
Sbjct 344 INRKPYLMLTWSPPPLADVRSGWLTLDYELRLKPEEGEEWETVFVGQQTQYKMFSLNPGK 403
Query 491 CYLITVT 497
Y++ +
Sbjct 404 KYIVQIH 410
Score = 185 bits (469), Expect = 3e-47, Method: Composition-based stats.
Identities = 63/267 (24%), Positives = 108/267 (40%), Gaps = 20/267 (7%)
Query 97 LNIQLTCNILTFGQLEQNVYGITIISG---LPPEKPKNLSCIVNEGKKMRCEWDGGRETH 153
+Q+ C +L G+ + I+ PPEKP C E + C W G +
Sbjct 200 YVVQVRC-MLDPGEWSEWSSERRILISGGLSPPEKPTITKCRSPEKETFTCWWKPGLDGG 258
Query 154 LETNFTLKSEWATHK-FADCK-AKRDTPTSCTVDYSTVYFVN-IEVWVEAENALGKVTSD 210
TN+TL + +C + P SC D F + V+A N +G +SD
Sbjct 259 HPTNYTLLYSKEGEEQVYECPDYRTAGPNSCYFDKKHTSFWTVYNITVKATNEMGSNSSD 318
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSS--ILKLTWTNPSIKSV----IILKYNIQYRTK 264
D Y V+P+PP N+++ + ++ L LTW+ P + V + L Y ++ + +
Sbjct 319 PHYVDVTYIVQPDPPANVTLELKKPINRKPYLMLTWSPPPLADVRSGWLTLDYELRLKPE 378
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
+ W + ++ + + L P +Y+ +I C D G WS+WS E D
Sbjct 379 EGEEWETV----FVGQQTQYKMFSLNPGKKYIVQIHCKP-DHHGSWSEWSSENYIEIPND 433
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVW 351
K W + + + + W
Sbjct 434 FRVKDMIVWIVLGVLSSLIC--LIMSW 458
Score = 84.1 bits (206), Expect = 3e-15, Method: Composition-based stats.
Identities = 87/558 (16%), Positives = 164/558 (29%), Gaps = 41/558 (7%)
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW 269
+ P P + + E+ + W S + Y + Y
Sbjct 16 PLTTVGLTSQSFPGKPKIIRCRSLEKETFSCW--WKPGSDG-GLPTNYTLFYSKDSEEKI 72
Query 270 SQIPPEDTASTRSSFTVQDL-KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
+ P T+ S + ++ +T Y + E G S+ S+
Sbjct 73 YECPDYRTSGPNSCYFNRNYTNSWTTYNITVTATNEIG----SNSSDPQYVDVTSIV-QP 127
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK-ILDYEVTLT-RWKSHLQNYTVN-AT 385
++ + W +A+ + YE+ L K + V T
Sbjct 128 GSPVNLTLETQRYANIMYLWAKWSPPLLADASSNHLYHYELRLKPEEKEEWETVPVGVQT 187
Query 386 KLTVNLTNDRYLATLTVRNLVGKSDAA------VLTIPACDFQATHPVMDLKAFPKDNML 439
+ +N N + VR ++ + + + I P + P+
Sbjct 188 QCKINRLNAGMRYVVQVRCMLDPGEWSEWSSERRILISGGLSPPEKPTITKCRSPEKETF 247
Query 440 WVEWTTPRESVKKYILEWCVLSDKAPCITDWQ----QEDGTVHRTYLRGNLAESKCYLIT 495
W + + + +L K ++ + G + + + + Y IT
Sbjct 248 TCWWKPGLD--GGHPTNYTLLYSKEGEEQVYECPDYRTAGPNSCYFDKKHTSFWTVYNIT 305
Query 496 VTPVYADGPGSPESIKAYLKQAP-PSKGPTVRTKKVGKNE----AVLEWDQLP-VDVQNG 549
V G S + + P V + +L W P DV++G
Sbjct 306 VKATNEMGSNSSDPHYVDVTYIVQPDPPANVTLELKKPINRKPYLMLTWSPPPLADVRSG 365
Query 550 FIR-NYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT- 607
++ +Y + + G E T+Y + SL Y+V++ D G +
Sbjct 366 WLTLDYELRLKPEEGEEWETVFVGQQTQYKMFSLNPGKKYIVQIHCKPDHHGSWSEWSSE 425
Query 608 --FTTP-KFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIA 664
P F ++ +V L+ L+ ++ +I I P VP P I
Sbjct 426 NYIEIPNDFRVKDMIVWIVLGVLSSLICLIMSWTMVLKGYRMIT-FILPPVPGPKIKGID 484
Query 665 QWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIE--ANDKKPFPEDLKSLDL---FKKEKI 719
T S + +D + IE + + + S D K KI
Sbjct 485 THLLETGKSEELLSALGCHGFPPTSDCEELLIEYLEVEDSEDHQLMPSHDSGRPSKNAKI 544
Query 720 NTEGHSSGIGGSSCMSSS 737
+ G SC S S
Sbjct 545 TLKETDRDSGRGSCDSPS 562
>sp|Q04594|PRLR_CHICK Prolactin receptor OS=Gallus gallus OX=9031
GN=PRLR PE=2 SV=1
Length=831
Score = 190 bits (481), Expect = 9e-49, Method: Composition-based stats.
Identities = 83/429 (19%), Positives = 147/429 (34%), Gaps = 49/429 (11%)
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH 153
I+S+ I L + T G Q+ P KPK + C E + C W G +
Sbjct 6 ISSVQIILFLPLTTVGLAGQSF----------PGKPKIIRCRSLEKETFSCWWKPGSDGG 55
Query 154 LETNFTLKSEWAT-HKFADCK-AKRDTPTSCTVDYSTVY-FVNIEVWVEAENALGKVTSD 210
L TN+TL + + +C + P SC + + + + V A N +G +SD
Sbjct 56 LPTNYTLFYSKDSEEEIYECPDYRTSGPNSCYFNKNHTSPWTTFNITVTATNEIGSNSSD 115
Query 211 HINFDPVYKVKPNPPHNLSVINSEELS-SILKLTWTNP---SIKSVIILKYNIQYRTKDA 266
D V+P P NL++ + L W+ P S + Y ++ + ++
Sbjct 116 PQYVDVTSIVQPGSPVNLTLETKRSANIMYLWAKWSPPLLADASSNHLYHYELRIKPEEK 175
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
W I ++ + L YV ++RC G WS+WS E + P
Sbjct 176 EEWETIS----VGVQTQCKINRLNAGMRYVVQVRCT--LDPGEWSEWSSERHIL----IP 225
Query 327 SKA-PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL-------Q 378
S P I + T WK P G +Y + ++ +
Sbjct 226 SGQSPPEKPTIIKCRSPEKETFTCWWK---PGLDGGHPTNYTLLYSKEGEEQVYECPDYR 282
Query 379 NYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA---- 432
N+ T+ Y T+ N +G + + + P +++
Sbjct 283 TAGPNSCYFDKKHTSFWTIYNITVRATNEMGSNSSDPHYVDVTYIVQPDPPVNVTLELKK 342
Query 433 -FPKDNMLWVEWTTPRESVKK---YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
+ L + W+ P + + LE+ + +W+ Y +L
Sbjct 343 PINRKPYLVLTWSPPPLADVRSGWLTLEYELRLKPEEGE-EWETIFVGQQTQYKMFSLNP 401
Query 489 SKCYLITVT 497
K Y+I +
Sbjct 402 GKKYIIQIH 410
Score = 188 bits (477), Expect = 3e-48, Method: Composition-based stats.
Identities = 76/343 (22%), Positives = 128/343 (37%), Gaps = 36/343 (10%)
Query 37 VVQLHSNFTAVCVLKE---------KCMDYFHVNANYIVWKTNHFTIPKEQY----TIIN 83
+VQ S K K +A+ I E+ TI
Sbjct 124 IVQPGSPVNLTLETKRSANIMYLWAKWSPPLLADASSNHLYHYELRIKPEEKEEWETISV 183
Query 84 RTASSVTFTDIAS---LNIQLTCNILTFGQLEQ--NVYGITIISGL-PPEKPKNLSCIVN 137
+ + + +Q+ C + G+ + + I I SG PPEKP + C
Sbjct 184 GVQTQCKINRLNAGMRYVVQVRCTL-DPGEWSEWSSERHILIPSGQSPPEKPTIIKCRSP 242
Query 138 EGKKMRCEWDGGRETHLETNFTLKSEWATHK-FADCK-AKRDTPTSCTVDYSTVYFVN-I 194
E + C W G + TN+TL + +C + P SC D F
Sbjct 243 EKETFTCWWKPGLDGGHPTNYTLLYSKEGEEQVYECPDYRTAGPNSCYFDKKHTSFWTIY 302
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS--ILKLTWTNPSIKSV 252
+ V A N +G +SD D Y V+P+PP N+++ + ++ L LTW+ P + V
Sbjct 303 NITVRATNEMGSNSSDPHYVDVTYIVQPDPPVNVTLELKKPINRKPYLVLTWSPPPLADV 362
Query 253 ----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
+ L+Y ++ + ++ W I ++ + + L P +Y+ +I C D G
Sbjct 363 RSGWLTLEYELRLKPEEGEEWETI----FVGQQTQYKMFSLNPGKKYIIQIHCKP-DHHG 417
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
WS+WS E D K W + + + + W
Sbjct 418 SWSEWSSENYIQIPNDFRVKDMIVWIVLGVLSSLIC--LIMSW 458
Score = 88.4 bits (217), Expect = 1e-16, Method: Composition-based stats.
Identities = 87/546 (16%), Positives = 167/546 (31%), Gaps = 41/546 (8%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P P + + E+ + W S + Y + Y + P T+
Sbjct 28 PGKPKIIRCRSLEKETFSCW--WKPGSDG-GLPTNYTLFYSKDSEEEIYECPDYRTSGPN 84
Query 282 SSFTVQD-LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
S + ++ P+T + + E G S+ S+ ++
Sbjct 85 SCYFNKNHTSPWTTFNITVTATNEIG----SNSSDPQYVDVTSIV-QPGSPVNLTLETKR 139
Query 341 TQGYRTVQLVWKTLPPFEANGK-ILDYEVTLT-RWKSHLQNYTVN-ATKLTVNLTNDRYL 397
+ + W +A+ + YE+ + K + +V T+ +N N
Sbjct 140 SANIMYLWAKWSPPLLADASSNHLYHYELRIKPEEKEEWETISVGVQTQCKINRLNAGMR 199
Query 398 ATLTVRNLVGKSDAAV------LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK 451
+ VR + + + + IP+ P + P+ W +
Sbjct 200 YVVQVRCTLDPGEWSEWSSERHILIPSGQSPPEKPTIIKCRSPEKETFTCWWKPGLD--G 257
Query 452 KYILEWCVLSDKAPCITDWQ----QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
+ + +L K ++ + G + + + + Y ITV G S
Sbjct 258 GHPTNYTLLYSKEGEEQVYECPDYRTAGPNSCYFDKKHTSFWTIYNITVRATNEMGSNSS 317
Query 508 ESIKAYLKQAP-PSKGPTVRTKKVGKNE----AVLEWDQLP-VDVQNGFIR-NYTIFYRT 560
+ + P V + VL W P DV++G++ Y + +
Sbjct 318 DPHYVDVTYIVQPDPPVNVTLELKKPINRKPYLVLTWSPPPLADVRSGWLTLEYELRLKP 377
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT---FTTP-KFAQG 616
G E T+Y + SL Y++++ D G + P F
Sbjct 378 EEGEEWETIFVGQQTQYKMFSLNPGKKYIIQIHCKPDHHGSWSEWSSENYIQIPNDFRVK 437
Query 617 EIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF 676
++ +V L+ L+ ++ +I + P VP P I T
Sbjct 438 DMIVWIVLGVLSSLICLIMSWTMVLKGYRMITFML-PPVPGPKIKGIDTHLLETGKSEEL 496
Query 677 NSKDQMYSDGNFTDVSVVEIE--ANDKKPFPEDLKSLDL---FKKEKINTEGHSSGIGGS 731
S + +D + IE + + + S D K KI + S G
Sbjct 497 LSALGCHGLPPTSDCEELLIEYLEVEDSEDQQLMPSHDNGHPSKNAKITRKETDSDSGRG 556
Query 732 SCMSSS 737
SC S S
Sbjct 557 SCDSPS 562
>sp|O97394|SDK_DROME Protein sidekick OS=Drosophila melanogaster
OX=7227 GN=sdk PE=1 SV=2
Length=2224
Score = 192 bits (488), Expect = 9e-49, Method: Composition-based stats.
Identities = 94/520 (18%), Positives = 162/520 (31%), Gaps = 49/520 (9%)
Query 126 PEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
P P N+S R WD G+ + +TL + + T
Sbjct 1374 PGVPSNVSFPDVSLTMARIIWDVPVDPNGKILAYQVTYTLNGSAMLNYSREFPPSDRTFR 1433
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ + A+ LG + + + + +P P + S+ +
Sbjct 1434 ATELLPGK----YYSFSCTAQTRLGWGKIATALVYTTNNRERPQAPSVPQISRSQIQAHQ 1489
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ +WT + Y ++ R ++ W + PE + SSFT L+P+ Y FRI
Sbjct 1490 ITFSWTPGRDGFAPLRYYTVEMR-ENEGRWQPL-PERVDPSLSSFTAVGLRPYMTYQFRI 1547
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
+ + G +S E T P+ + + T +V++ W L
Sbjct 1548 QATNDLGPSAFSR--ESVIVRTLPAAPAVGVGGLKVVPITTT----SVRVQWSALETALW 1601
Query 360 NG--KILDYEVTLTRW-----------KSHLQNYTVNATKLTVNLTNDRYLATLTVRNLV 406
NG Y + + K+ + N+ L+ + Y + N
Sbjct 1602 NGDASTGGYRILYQQLSDFPTALQSTPKTDVHGINENSVVLSDLQQDRNYEIVVLPFNSQ 1661
Query 407 GKSDAAVLT-IPACDFQATHPVMDLKAFP-KDNMLWVEWTTPR-----ESVKKYILEWCV 459
G A + + T + A P + + W P+ + Y + + V
Sbjct 1662 GPGPATPPAAVYVGEAVPTGEPRAVDAAPISSTEVRLLWKPPKQSMQNGDILGYKIYYLV 1721
Query 460 LSDKA--PCITDWQQEDGTVHRTYLRGNLA---ESKCYLITVTPVYADGPGS-PESIKAY 513
W++E V T +L + Y I + G G I
Sbjct 1722 TYSPQALEPGRKWEEEIEVVSATATSHSLVFLDKFTEYRIQLLAFNPAGDGPRSAPITVK 1781
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET---AVNV 570
PS +R + + WD P NG I Y + Y T NE V
Sbjct 1782 TLPGVPSAPLHLRFSDITMQSLEVTWD--PPKFLNGEILGYLVTYETTEENEKFSKQVKQ 1839
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
S+T + +L + Y + A T G TT
Sbjct 1840 KVSNTTLRVQNLEEEVTYTFTVRAQTSVDYGPGISENVTT 1879
Score = 182 bits (461), Expect = 2e-45, Method: Composition-based stats.
Identities = 111/608 (18%), Positives = 190/608 (31%), Gaps = 61/608 (10%)
Query 58 FHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS---LNIQL-TCNILTFGQLEQ 113
++++ +V I + TA+S + +++ CN + +
Sbjct 1202 YNISYKQLVKTPGTIKYVPRSVVIEDHTANSHVLDSLEEWTLYEVKMNACNDVGCSKESD 1261
Query 114 NVYGITIISGLPPEKPKNLSCIVNEGKKMRCEW-------DGGRETHLETNFTLKSEWAT 166
T + +P P ++ + +W G+ + +
Sbjct 1262 TAVERTREA-VPSYGPLDVQANATSSTTVVVQWGEVPRQHRNGQIDGYKVFYAAADRGQQ 1320
Query 167 HKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK--VTSDHINFDPVYKVKPNP 224
T+ T +V V V A LG +++ I P
Sbjct 1321 VLHKTIPNNATFTTTLT---ELKKYVVYHVQVLAYTRLGNGALSTPPIRVQTFEDT-PGV 1376
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P N V + ++ ++ W P + IL Y + Y T + S E S R+ F
Sbjct 1377 PSN--VSFPDVSLTMARIIWDVPVDPNGKILAYQVTY-TLNGSAMLNYSREFPPSDRT-F 1432
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGY 344
+L P Y F G W + T +APS
Sbjct 1433 RATELLPGKYYSFSCTAQTRLG---WGKIATALVYTTNNRERPQAPSVPQI--SRSQIQA 1487
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTR----WKSHLQNYTVNATKLTVNLTND--RYLA 398
+ W A + Y V + W+ + + + T Y
Sbjct 1488 HQITFSWTPGRDGFA--PLRYYTVEMRENEGRWQPLPERVDPSLSSFTAVGLRPYMTYQF 1545
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMD--LKAFP-KDNMLWVEWTT-------PRE 448
+ N +G S + ++ A V LK P + V+W+
Sbjct 1546 RIQATNDLGPSAFSRESVIVRTLPAAPAVGVGGLKVVPITTTSVRVQWSALETALWNGDA 1605
Query 449 SVKKYILEWCVLSD--KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
S Y + + LSD A T G + + +L + + Y I V P + GPG
Sbjct 1606 STGGYRILYQQLSDFPTALQSTPKTDVHGINENSVVLSDLQQDRNYEIVVLPFNSQGPGP 1665
Query 507 P-ESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY------ 558
Y+ +A P+ P V + E L W +QNG I Y I+Y
Sbjct 1666 ATPPAAVYVGEAVPTGEPRAVDAAPISSTEVRLLWKPPKQSMQNGDILGYKIYYLVTYSP 1725
Query 559 RTIIG----NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFA 614
+ + E V ++ T ++L L T Y +++ A+ G DGP T K
Sbjct 1726 QALEPGRKWEEEIEVVSATATSHSLVFLDKFTEYRIQLLAFNPAG--DGPRSAPITVKTL 1783
Query 615 QGEIEAIV 622
G A +
Sbjct 1784 PGVPSAPL 1791
Score = 172 bits (436), Expect = 2e-42, Method: Composition-based stats.
Identities = 101/664 (15%), Positives = 202/664 (30%), Gaps = 76/664 (11%)
Query 22 GELLDPCGYISPE------SPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFT-- 73
G +P + PV + S + ++ + I+ +
Sbjct 739 GSPSEPSNVVELPQEAPSGPPVGFVGSARSMSEIITQWQPPLEEHRNGQILGYILRYRLF 798
Query 74 ----IPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYG----ITIISGLP 125
+P I N + ++ + + I + + VY I G+P
Sbjct 799 GYNNVPWSYQNITNEAQRNFLIQELITWKDYIV-QIAAYNNMGVGVYTEGSKIKTKEGVP 857
Query 126 PEKPKNLSCIVNEGKKMRCEWDGG---RETHLETNFTLKS----------EWATHKFADC 172
P N+ RC W + + + +++ +
Sbjct 858 EAPPTNVKVEAINSTAARCRWTPPNPQQINGINQGYKIQAWQRRLIDGEWRDIERRMKTV 917
Query 173 KAKRDTP--TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
P + F + V G + P+ +
Sbjct 918 PPSLIDPLAEQTAILGGLEKFTEYNISVLCFTDPGDGVASSQVAVMTMDDVPD--EVTGL 975
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ +K+ W P + I+ Y ++Y+ KD + + + + TV L+
Sbjct 976 HFDDVSDRSVKVLWAPPRASNGILTGYTVRYQVKDRPD--TLKSFNLTADDTELTVNQLQ 1033
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
T Y F I G G T + +V L
Sbjct 1034 ATTHYWFEIVAWTRVGSGIP-------KTATIQSGVEPVLPHAPTALALSNIEAFSVVL- 1085
Query 351 WKTLPPFEANGKILDYEVTLTRWKS-------HLQNYTVNATKLTVNLTNDRYLATLTVR 403
+ P F+ N I ++V ++ + + +T + +Y L+
Sbjct 1086 -QFTPGFDGNSSITKWKVEGQTARNMTWFTICEINDPDAETLTVTGLVPFTQYRLRLSAS 1144
Query 404 NLVGKSDAAVLT--IPACDFQATHPVMDLKAFPKD-NMLWVEWTTPR-----ESVKKYIL 455
N+VG S + T + HP ++ L V W + + + Y +
Sbjct 1145 NVVGSSKPSEATKDFQTIQARPKHPPFNVTVRAMSAQQLRVRWIPLQQTEWYGNPRGYNI 1204
Query 456 EWCVLSDKAPCITDWQQEDGTVH----RTYLRGNLAESKCYLITVTPVYADGPGS-PESI 510
+ L K P + + +++ +L E Y + + G ++
Sbjct 1205 SYKQLV-KTPGTIKYVPRSVVIEDHTANSHVLDSLEEWTLYEVKMNACNDVGCSKESDTA 1263
Query 511 KAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
++A PS GP V+ V++W ++P +NG I Y +FY + ++
Sbjct 1264 VERTREAVPSYGPLDVQANATSSTTVVVQWGEVPRQHRNGQIDGYKVFYAAADRGQQVLH 1323
Query 570 ---VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFA-QGEIEAIVVPV 625
+++ TL+ L +Y V++ AYT G +TP Q + VP
Sbjct 1324 KTIPNNATFTTTLTELKKYVVYHVQVLAYTRLGNG-----ALSTPPIRVQTFEDTPGVPS 1378
Query 626 CLAF 629
++F
Sbjct 1379 NVSF 1382
Score = 167 bits (423), Expect = 8e-41, Method: Composition-based stats.
Identities = 88/511 (17%), Positives = 157/511 (31%), Gaps = 54/511 (11%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNF-TLKSEWATHKFADCKAKRDTPTSCTV 184
P P+ +S + ++ W GR+ + T++ ++ + D S
Sbjct 1475 PSVPQ-ISRSQIQAHQITFSWTPGRDGFAPLRYYTVEMRENEGRWQPLPERVDPSLSSFT 1533
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH----NLSVINSEELSSIL 240
++ + ++A N LG S + + P P L V ++ +
Sbjct 1534 AVGLRPYMTYQFRIQATNDLG--PSAFSRESVIVRTLPAAPAVGVGGLKV--VPITTTSV 1589
Query 241 KLTWTNPS----IKSVIILKYNIQYRTKD---ASTWSQIPPEDTASTRSSFTVQDLKPFT 293
++ W+ Y I Y+ + S + +S + DL+
Sbjct 1590 RVQWSALETALWNGDASTGGYRILYQQLSDFPTALQSTPKTDVHGINENSVVLSDLQQDR 1649
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
Y + G G + A+ E P+ P S T V+L+WK
Sbjct 1650 NYEIVVLPFNSQGPG---PATPPAAVYVGEAVPTGEPRAVDAAPISST----EVRLLWKP 1702
Query 354 LPPFEANGKILDYEVTL------------TRWKSHLQNYTVNATK--LTVNLTNDRYLAT 399
NG IL Y++ +W+ ++ + AT L Y
Sbjct 1703 PKQSMQNGDILGYKIYYLVTYSPQALEPGRKWEEEIEVVSATATSHSLVFLDKFTEYRIQ 1762
Query 400 LTVRNLVGKSD-AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR---ESVKKYIL 455
L N G +A +T+ + P+ + L V W P+ + Y++
Sbjct 1763 LLAFNPAGDGPRSAPITVKTLPGVPSAPLHLRFSDITMQSLEVTWDPPKFLNGEILGYLV 1822
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA--DGPGSPESIKAY 513
+ + +Q+ T NL E Y TV + GPG E++
Sbjct 1823 TYETTEENEKFSKQVKQKVSNT--TLRVQNLEEEVTYTFTVRAQTSVDYGPGISENVTTG 1880
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDS 572
+ P + K + + W P G I Y I + T +
Sbjct 1881 PQDGSPVAPRDLILTK-TLSSVEMHWINGP--SGRGPILGYLIEAKKRDDSRWTKIEQTR 1937
Query 573 S----HTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ L T Y R+ AY G
Sbjct 1938 KGMMQDFTVSYHILMPSTAYTFRVIAYNRYG 1968
Score = 139 bits (351), Expect = 3e-32, Method: Composition-based stats.
Identities = 100/625 (16%), Positives = 186/625 (30%), Gaps = 70/625 (11%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P V L T C K V N ++ + P I A
Sbjct 552 PVDTTVLLGLTATLQC----KVSSDPSVPYNIDWYREGQSSTPISNSQRIGVQADGQ--L 605
Query 93 DIASLNIQLTCNILTF--GQLEQNVYGITIISGLPPEKPKNLSCIV---NEGKKMRCEWD 147
+I ++ + + P P N+ + + + W
Sbjct 606 EIQAVRASDVGSYACVVTSPGGNETRAARLSVIELPFPPSNVKVERLPEPQQRSINVSWT 665
Query 148 GGRETHLETNFTLKSEWATHKFADCKAKRDTP--------TSCTVDYSTVYFVN------ 193
G + + + + + P ++ + D + N
Sbjct 666 PGFDGNSPISKFIIQRREVSELEKFVGPVPDPLLNWITELSNVSADQRWILLENLKAATV 725
Query 194 IEVWVEAENALGK-VTSDHINFDPVYKVKP-NPPHNLSVINSEELSSILKLTWTNP--SI 249
+ V A N +G+ S+ N + + P PP V ++ +S I+ W P
Sbjct 726 YQFRVSAVNRVGEGSPSEPSNVVELPQEAPSGPPVGF-VGSARSMSEIIT-QWQPPLEEH 783
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
++ IL Y ++YR + T + +F +Q+L + +Y+ +I G G
Sbjct 784 RNGQILGYILRYRLFGYNNVPWSYQNITNEAQRNFLIQELITWKDYIVQIAAYNNMGVGV 843
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
+++ S+ T E P P+ + T + W P + NG Y++
Sbjct 844 YTEGSK---IKTKEGVPEAPPTNVKVEAINSTAA----RCRWTPPNPQQINGINQGYKIQ 896
Query 370 LT-------RWKSHLQNYTVNATKLTVNLTN-----------DRYLATLTVRNLVGKS-- 409
W+ + L L Y ++ G
Sbjct 897 AWQRRLIDGEWRDIERRMKTVPPSLIDPLAEQTAILGGLEKFTEYNISVLCFTDPGDGVA 956
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITD 469
+ V + D + D + V W PR S + + V
Sbjct 957 SSQVAVMTMDDVPDEVTGLHFDDV-SDRSVKVLWAPPRAS-NGILTGYTVRYQVKDRPDT 1014
Query 470 WQQEDGTVHRTYLRGN-LAESKCYLITVTPVYADGPGSPE--SIKAYLKQAPPSKGPTVR 526
+ + T T L N L + Y + G G P+ +I++ ++ P +
Sbjct 1015 LKSFNLTADDTELTVNQLQATTHYWFEIVAWTRVGSGIPKTATIQSGVEPVLPHAPTALA 1074
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTLSSL 582
+ VL+ P N I + + +T +N D T++ L
Sbjct 1075 LSNIEAFSVVLQ--FTPGFDGNSSITKWKVEGQTARNMTWFTICEIN-DPDAETLTVTGL 1131
Query 583 TSDTLYMVRMAAYTDEGGKDGPEFT 607
T Y +R++A G E T
Sbjct 1132 VPFTQYRLRLSASNVVGSSKPSEAT 1156
Score = 118 bits (294), Expect = 2e-25, Method: Composition-based stats.
Identities = 70/386 (18%), Positives = 120/386 (31%), Gaps = 38/386 (10%)
Query 146 WDGGRETHLETNFTLKSEWATHKFADCKAKRDTP---TSCTVDYSTVYFVNIEVWVEAEN 202
W+G T + K D + V N E+ V N
Sbjct 1601 WNGDASTGGY-RILYQQLSDFPTALQSTPKTDVHGINENSVVLSDLQQDRNYEIVVLPFN 1659
Query 203 ALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP--SIKSVIILKYNI 259
+ G + V P +V + S+ ++L W P S+++ IL Y I
Sbjct 1660 SQGPGPATPPAAVYVGEAVPTGEPR--AVDAAPISSTEVRLLWKPPKQSMQNGDILGYKI 1717
Query 260 QYRTKDAS-------TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
Y + W + E ++T +S ++ L FTEY ++ G G
Sbjct 1718 YYLVTYSPQALEPGRKWEE-EIEVVSATATSHSLVFLDKFTEYRIQLLAFNPAGDG---P 1773
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR 372
S + T PS + +++++ W PP NG+IL Y VT
Sbjct 1774 RSAPITVKTLPGVPSAPLHLRF-----SDITMQSLEVTWD--PPKFLNGEILGYLVTYET 1826
Query 373 WKSHLQ-----NYTVNATKLTVNLTNDR--YLATLTVRNLVGKSDAAVLTIPA-CDFQAT 424
+ + + V+ T L V + Y T+ + V + +
Sbjct 1827 TEENEKFSKQVKQKVSNTTLRVQNLEEEVTYTFTVRAQTSVDYGPGISENVTTGPQDGSP 1886
Query 425 HPVMDLKAFPKDNMLWVEW---TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
DL + + + W + R + Y++E D + ++ T
Sbjct 1887 VAPRDLILTKTLSSVEMHWINGPSGRGPILGYLIEAKKRDDSRWTKIEQTRKGMMQDFTV 1946
Query 482 LRGNLAESKCYLITVTPVYADGPGSP 507
L S Y V G P
Sbjct 1947 SYHILMPSTAYTFRVIAYNRYGISFP 1972
Score = 98.4 bits (243), Expect = 2e-19, Method: Composition-based stats.
Identities = 53/310 (17%), Positives = 103/310 (33%), Gaps = 41/310 (13%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRET-----------HLETNFTLKSEWATHKFADC 172
+P +P+ + ++R W +++ + ++ ++ K+ +
Sbjct 1678 VPTGEPRAVDAAPISSTEVRLLWKPPKQSMQNGDILGYKIYYLVTYSPQALEPGRKWEEE 1737
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVI 231
+ F + + A N G S I + V P L +
Sbjct 1738 IEVVSATATSHSLVFLDKFTEYRIQLLAFNPAGDGPRSAPITVKTLPGVPSAP---LHLR 1794
Query 232 NSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
S+ L++TW P + IL Y + Y T + + + S + VQ+L+
Sbjct 1795 FSDITMQSLEVTWDPPKFLNGEILGYLVTYETTEENEKFSKQVKQKVSNTT-LRVQNLEE 1853
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
Y F +R G SE + + P D T+ +V++ W
Sbjct 1854 EVTYTFTVRAQTSVDYGPGI--SENVTTGPQDGSPVAP------RDLILTKTLSSVEMHW 1905
Query 352 KTLPPFEANGKILDYEVTL-----TRW-------KSHLQNYTVNATKLTVNLTNDRYLAT 399
+ G IL Y + +RW K +Q++TV+ + + + Y
Sbjct 1906 --INGPSGRGPILGYLIEAKKRDDSRWTKIEQTRKGMMQDFTVSYH---ILMPSTAYTFR 1960
Query 400 LTVRNLVGKS 409
+ N G S
Sbjct 1961 VIAYNRYGIS 1970
>sp|Q62234|MYOM1_MOUSE Myomesin-1 OS=Mus musculus OX=10090 GN=Myom1
PE=1 SV=2
Length=1667
Score = 190 bits (483), Expect = 3e-48, Method: Composition-based stats.
Identities = 105/630 (17%), Positives = 188/630 (30%), Gaps = 82/630 (13%)
Query 41 HSNFTAVC--VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASS--VTFTDIAS 96
+ C V+ + + + W N + ++ + + +TF+ +
Sbjct 399 GETMSLGCRVVITPEIKHF----QPEVQWYRNGAPVSPSKWVQPHWSGDRATLTFSHLNK 454
Query 97 LNIQLTCNILTFGQLEQN------VYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD-GG 149
+ L + G+ + V P P ++ + + W
Sbjct 455 EDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVVSLDANKDYIIISWKQPA 514
Query 150 RETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG-- 205
+ F K E T ++ C V + V A N G
Sbjct 515 VDGGSPILGYFIDKCEVGTDTWSQCNDTPVKFARFPVTGLIEGR-SYIFRVRAVNKTGIG 573
Query 206 --KVTSDHINF--------------------------DPVYKVKPNPPHNLSVINSEELS 237
S+ + +P V P PP +LSV +E
Sbjct 574 LPSRVSEPVAALDPAEKARLKSHPSAPWTGQIIVTEEEPTEGVIPGPPTDLSV--TEATR 631
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
S + L+W P + + Y ++ A W ++ E F + DL Y F
Sbjct 632 SYVVLSWKPPGQRGHEGIMYFVEKCDVGAENWQRVNTELPV-KSPRFALFDLVEGKSYRF 690
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW-KTLPP 356
R+RC G G S+ +E D P KI PS +V + W ++
Sbjct 691 RVRCSNSAGVGEPSETTEVTVVGDKLDIPKAP----GKIIPSRNTDT-SVVVSWEESRDA 745
Query 357 FEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND--RYLATLTVRNLVGKS----D 410
E G ++ V + N V ++ T + Y+ + N G S D
Sbjct 746 KELVGYYIEASVVGSGKWEPCNNNPVKGSRFTCHGLTTAQSYIFRVRAVNAAGLSEYSQD 805
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW 470
+ + + A P + + L + + +L +
Sbjct 806 SEAIEVKAAIGGGVSPDVWPQLSDTPGGLTDSRGGMNGASPPTSQKDALLGSNPNKPSPP 865
Query 471 -------QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
Q+E TV + + + + S K A PS
Sbjct 866 SSPSSRGQKEVSTVSESVQEPLSSPPQE-----AAPEEEQSQSEPPKKKKDPVAVPSAPY 920
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN----ETAVNVDS-SHTEYT 578
+ + ++ VL W Q P I Y + YR ++G N+ + S Y
Sbjct 921 DITCLESFRDSMVLGWKQ-PDTTGGAEITGYYVNYREVVGEVPGKWREANIKAVSDAAYK 979
Query 579 LSSLTSDTLYMVRMAAYTDEG-GKDGPEFT 607
+S+L +TLY +++A G G
Sbjct 980 ISNLKENTLYQFQVSAMNIAGLGAPSTVSE 1009
Score = 157 bits (397), Expect = 7e-38, Method: Composition-based stats.
Identities = 85/525 (16%), Positives = 161/525 (31%), Gaps = 54/525 (10%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLET--NFTLKSEWATHKFADCKAKRDTPT 180
G+ P P +LS + W + E F K + + + +
Sbjct 615 GVIPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCDVGAENWQRVNTELPVKS 674
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL-SVINSEELSSI 239
+ V + V N+ G V K + P +I S +
Sbjct 675 PRFALFDLVEGKSYRFRVRCSNSAGVGEPSETTEVTVVGDKLDIPKAPGKIIPSRNTDTS 734
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ ++W ++ Y I+ + W P + S FT L Y+FR+
Sbjct 735 VVVSWEESRDAKELV-GYYIEASVVGSGKWE--PCNNNPVKGSRFTCHGLTTAQSYIFRV 791
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
R + G +S SE +P W ++ S T G T ++
Sbjct 792 RAVNAAGLSEYSQDSEAIEVKAAIGG-GVSPDVWPQL--SDTPGGLT-----------DS 837
Query 360 NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLV--GKSDAAVLTIP 417
G + ++ + L + + + + + + ++ S
Sbjct 838 RGGMNGASPPTSQKDALLGSNPNKPSPPSSPSSRGQKEVSTVSESVQEPLSSPPQEAAPE 897
Query 418 ACDFQATHP-----VMDLKAFPKD--------NMLWVEWTTP----RESVKKYILEWCVL 460
Q+ P + + + P D + + + W P + Y + + +
Sbjct 898 EEQSQSEPPKKKKDPVAVPSAPYDITCLESFRDSMVLGWKQPDTTGGAEITGYYVNYREV 957
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY--LKQ-- 516
+ P Y NL E+ Y V+ + G G+P ++ ++
Sbjct 958 VGEVPGKWREANIKAVSDAAYKISNLKENTLYQFQVSAMNIAGLGAPSTVSECFKCEEWT 1017
Query 517 -APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI---IGNETAVNVDS 572
A P +V+ +V KN VL+W PV + Y + + +N +
Sbjct 1018 IAVPGPPHSVKLSEVRKNSLVLQWKP-PVYSGRTPVTGYFVDLKEASAKDDQWRGLNEAA 1076
Query 573 SHTEY-TLSSLTSDTLYMVRMAAYTDEGGKD-----GPEFTFTTP 611
+Y + L T Y+ R+ A G GP T P
Sbjct 1077 IVNKYLRVQGLKEGTSYVFRVRAVNQAGVGKPSDLAGPVVAETRP 1121
Score = 93.0 bits (229), Expect = 8e-18, Method: Composition-based stats.
Identities = 51/215 (24%), Positives = 75/215 (35%), Gaps = 17/215 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRE-THLETNFTLKSEWATHKFADCKAKRDT 178
P P +++C+ + M W GG E T N+ K+ + K +
Sbjct 915 VPSAPYDITCLESFRDSMVLGWKQPDTTGGAEITGYYVNYREVVGEVPGKWREANIKAVS 974
Query 179 PTSCTVDYSTVYFVNIEVWVEAEN--ALGKVTSDHINF--DPVYKVKPNPPHNLSVINSE 234
+ + + V A N LG ++ F + P PPH SV SE
Sbjct 975 DAA-YKISNLKENTLYQFQVSAMNIAGLGAPSTVSECFKCEEWTIAVPGPPH--SVKLSE 1031
Query 235 ELSSILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
+ L L W P + Y + + A + A VQ LK T
Sbjct 1032 VRKNSLVLQWKPPVYSGRTPVTGYFVDLKEASAKDDQWRGLNEAAIVNKYLRVQGLKEGT 1091
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
YVFR+R + + G G SD A + E RP
Sbjct 1092 SYVFRVRAVNQAGVGKPSD---LAGPVVAETRPGT 1123
Score = 75.7 bits (184), Expect = 2e-12, Method: Composition-based stats.
Identities = 43/292 (15%), Positives = 79/292 (27%), Gaps = 44/292 (15%)
Query 368 VTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI-----PACDFQ 422
V+ ++W + + D L T+ VR + +
Sbjct 430 VSPSKWVQPHWSGDRATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGA 489
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
P+ + + + + W P IL + + + T W Q + T +
Sbjct 490 PAAPLDVVSLDANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDT-WSQCNDTPVKFAR 548
Query 483 R--GNLAESKCYLITVTPVYADGPGSPESI--------------------------KAYL 514
L E + Y+ V V G G P +
Sbjct 549 FPVTGLIEGRSYIFRVRAVNKTGIGLPSRVSEPVAALDPAEKARLKSHPSAPWTGQIIVT 608
Query 515 KQAP-----PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAV 568
++ P P + + ++ VL W G + Y + + N V
Sbjct 609 EEEPTEGVIPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM--YFVEKCDVGAENWQRV 666
Query 569 N--VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEI 618
N + + L L Y R+ G + E T T + +I
Sbjct 667 NTELPVKSPRFALFDLVEGKSYRFRVRCSNSAGVGEPSETTEVTVVGDKLDI 718
>sp|O94856|NFASC_HUMAN Neurofascin OS=Homo sapiens OX=9606 GN=NFASC
PE=1 SV=4
Length=1347
Score = 188 bits (478), Expect = 9e-48, Method: Composition-based stats.
Identities = 78/429 (18%), Positives = 140/429 (33%), Gaps = 33/429 (8%)
Query 204 LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT 263
L + + K +P+ P +L + + E S ++LTW + I Y +Q+
Sbjct 610 LADQATPTNRLAALPKGRPDRPRDLELTDLAERS--VRLTWIPGDANNSPITDYVVQFEE 667
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+ +S ++ L P+ Y FR+ + E G + S SE
Sbjct 668 DQFQPGVWHDHSKYPGSVNSAVLR-LSPYVNYQFRVIAINEVGSSHPSLPSERYRT---- 722
Query 324 DRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTL--TRWKSHLQNY 380
S AP D + +++ W + A G L Y V + N
Sbjct 723 ---SGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNV 779
Query 381 TVNATKLTVNLT--NDRYLATLTVRNLVGKSDAAVLTI--PACDFQATHPVMDLKAFPKD 436
TV ++ V T Y + N GK I D+ P
Sbjct 780 TVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNS 839
Query 437 NMLWVEWTTP-RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN--------LA 487
+ ++W ++V+ + E+ + + + G+ L
Sbjct 840 TAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLF 899
Query 488 ESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDV 546
Y + + V G G E+ + + PS R ++ LEWD +
Sbjct 900 PYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDH--PEH 957
Query 547 QNGFIRNYTIFY----RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
NG + YT+ Y T +G + N + T++T+ + Y ++A T G +
Sbjct 958 PNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGE 1017
Query 603 GPEFTFTTP 611
P
Sbjct 1018 AVTEESPAP 1026
Score = 121 bits (304), Expect = 8e-27, Method: Composition-based stats.
Identities = 89/530 (17%), Positives = 165/530 (31%), Gaps = 61/530 (12%)
Query 30 YISPESPVVQLHSNFTAVC------VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIIN 83
Y PE V + + C LK YI + + +
Sbjct 525 YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAE 584
Query 84 RTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLP---PEKPKNLSCIVNEGK 140
R S T L+ L LT L ++ LP P++P++L +
Sbjct 585 RDQGSYTCVASTELDQDLAKAYLT--VLADQATPTNRLAALPKGRPDRPRDLELTDLAER 642
Query 141 KMRCEWDGG-RETHLETNFTLKSEWATHK---FADCKAKRDTPTSCTVDYSTVYFVNIEV 196
+R W G T++ ++ E + + D + S + S +VN +
Sbjct 643 SVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSP--YVNYQF 700
Query 197 WVEAENALGKVTSDHINFDPVYKVKPNPPHNL--SVINSEELSSILKLTWTNPSIKS--V 252
V A N +G +S Y+ PP + V + +++TWT + S
Sbjct 701 RVIAINEVG--SSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFG 758
Query 253 IILKYNIQYRTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
L+Y +++R ++ W+ + + V + Y R++ + GKG
Sbjct 759 PNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPV-----YVPYEIRVQAENDFGKGPEP 813
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
E G + ED P AP+ + L W + G++ +Y
Sbjct 814 ---ESVIGYSGEDYPRAAPTEVKV----RVMNSTAISLQWNRVYSDTVQGQLREYRAYYW 866
Query 372 RWKSHLQNYTVNATK-------------LTVNLTNDRYLATLTVRNLVGKSD-AAVLTIP 417
R S L+N V+ + ++ Y + V N G +
Sbjct 867 RESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFT 926
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEW---TTPRESVKKYILEWCVLSDKAPCITDWQQED 474
+ + P P + +EW P + Y L++ + +
Sbjct 927 TPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFS 986
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
+ Y T++ G G +A +++P P
Sbjct 987 PNQTKF-TVQRTDPVSRYRFTLSARTQVGSG-----EAVTEESP--APPN 1028
Score = 98.4 bits (243), Expect = 2e-19, Method: Composition-based stats.
Identities = 70/324 (22%), Positives = 110/324 (34%), Gaps = 40/324 (12%)
Query 122 SGLPPEK-PKNLSCIVNEGKKMRCEWDGGRET---HLETNFTLKSEWATHKFADCKAKRD 177
SG PPE P ++ M W T + +K W + +
Sbjct 723 SGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVK--WRRRETREAWNNVT 780
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP-NPPHNLSVINSEEL 236
S V T +V E+ V+AEN GK + P P + V
Sbjct 781 VWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKV--RVMN 838
Query 237 SSILKLTWTNPSIKSVIILKYNIQ-YRTKDASTWSQIPPEDTASTRSSFTVQD------- 288
S+ + L W + ++ ++ YR S + + R +
Sbjct 839 STAISLQW---NRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVV 895
Query 289 --LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
L P++ Y + + G G SE T E PS AP + P+ T
Sbjct 896 SRLFPYSNYKLEMVVVNGRGDG---PRSETKEFTTPEGVPS-APRRFRVRQPNLE----T 947
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKSH------LQNYTVNATKLTVNLTN--DRYLA 398
+ L W P NG ++ Y + + ++N++ N TK TV T+ RY
Sbjct 948 INLEWDH--PEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRF 1005
Query 399 TLTVRNLVGKSDAAVLTIPACDFQ 422
TL+ R VG +A PA +
Sbjct 1006 TLSARTQVGSGEAVTEESPAPPNE 1029
>sp|F1NWE3|PTPRS_CHICK Receptor-type tyrosine-protein phosphatase
S OS=Gallus gallus OX=9031 GN=PTPRS PE=1 SV=3
Length=1516
Score = 187 bits (474), Expect = 3e-47, Method: Composition-based stats.
Identities = 80/411 (19%), Positives = 152/411 (37%), Gaps = 43/411 (10%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A ++LG + + K P P V +E ++ + +TW + + Y I
Sbjct 303 AMSSLGVIEA---VAQITVKSLPKAPGTPVV--TETTATSITITWDSG--NPDPVSYYVI 355
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+Y++K QI + T + +++ L P +EY + + G+G SE
Sbjct 356 EYKSKSQDGPYQIKEDIT---TTRYSIGGLSPNSEYEIWVSAVNSIGQG---PPSESVVT 409
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK----S 375
T E P+ AP T+ + W+ P E NG+I Y V T S
Sbjct 410 RTGEQAPASAPRNV----QGRMLSSTTMIIQWEE--PVEPNGQIRGYRVYYTMEPDQPVS 463
Query 376 HLQNYTVNATKLTV---NLTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLK 431
+ Q + V+ + LT L ++ Y + VG + + + P+
Sbjct 464 NWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNFRA 523
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
+ + + W+ PR+ + I+++ +L + + + + ++ L +
Sbjct 524 EAKTETSIVLSWSPPRQEI---IVKYELLFKEGDHGREVPR-NFEPTTSFTVEGLKPNTE 579
Query 492 YLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
Y+ + A G G+ ++ Q+ + K V K +L W+ + N
Sbjct 580 YVFRLAARSALGLGAFTPEVRERTLQS--ILPKNFKVKMVTKTSVLLSWEF--PENYNSP 635
Query 551 IRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY-TDEGG 600
Y I Y N V+VD T+ +++L T Y + GG
Sbjct 636 -TPYKIQY-----NGLNVDVDGRTTKKLITNLKPHTFYNFVLMNRGNSMGG 680
Score = 151 bits (380), Expect = 8e-36, Method: Composition-based stats.
Identities = 87/514 (17%), Positives = 154/514 (30%), Gaps = 47/514 (9%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
I P S + N CV Y+ W + E + R +T
Sbjct 239 ILPVSHEIMPGGNVNITCV-------AVGSPMPYVKWMQGAEDLTPEDDMPVGRNVLELT 291
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
+ TC ++ + + V IT+ S P+ P + WD G
Sbjct 292 ---DVKDSANYTCVAMSSLGVIEAVAQITVKS--LPKAPGTPVVTETTATSITITWDSGN 346
Query 151 ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT-S 209
++ + + + + K D T+ E+WV A N++G+ S
Sbjct 347 PD--PVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPS 404
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW 269
+ + + + P N V S+ + + W P + I Y + Y +
Sbjct 405 ESVVTRTGEQAPASAPRN--VQGRMLSSTTMIIQWEEPVEPNGQIRGYRVYYTMEPDQPV 462
Query 270 SQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
S + + + TV L Y R+ G G SD T + P +
Sbjct 463 SNWQKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVGDGPLSD---PIQVKTQQGVPGQP 518
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS--HLQNYTVNATKL 387
+F + + ++ L W I+ YE+ + T
Sbjct 519 MNFR-----AEAKTETSIVLSWSPPRQE----IIVKYELLFKEGDHGREVPRNFEPTTSF 569
Query 388 TVNLT--NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT 445
TV N Y+ L R+ +G + Q+ P + + W
Sbjct 570 TVEGLKPNTEYVFRLAARSALGLGAFT-PEVRERTLQSILPKNFKVKMVTKTSVLLSWEF 628
Query 446 PRE--SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADG 503
P S Y +++ L+ DG + L NL Y +
Sbjct 629 PENYNSPTPYKIQYNGLNVD---------VDGRTTK-KLITNLKPHTFYNFVLMNRGNSM 678
Query 504 PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVL 537
G +++ A+ S+ P V K V+
Sbjct 679 GGLQQNVAAWTAANMLSRKPEVTHKPDADGNVVV 712
Score = 139 bits (350), Expect = 3e-32, Method: Composition-based stats.
Identities = 58/259 (22%), Positives = 102/259 (39%), Gaps = 23/259 (9%)
Query 375 SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK-SDAAVLTIPACDFQATHPVMDLKAF 433
+ + V L + D T + +G A +T+ + PV+
Sbjct 276 TPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPVVTET-- 333
Query 434 PKDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
+ + W + + V Y++E+ S P +Q ++ Y G L+ + Y
Sbjct 334 -TATSITITWDSGNPDPVSYYVIEYKSKSQDGP----YQIKEDITTTRYSIGGLSPNSEY 388
Query 493 LITVTPVYADGPGSP-ESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGF 550
I V+ V + G G P ES+ + P+ P V+ + + +++W++ NG
Sbjct 389 EIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQGRMLSSTTMIIQWEE--PVEPNGQ 446
Query 551 IRNYTIFYR----TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
IR Y ++Y + N NVD S T+ SL D Y VR+ A+T G DGP
Sbjct 447 IRGYRVYYTMEPDQPVSNWQKHNVDDSLLT-TVGSLLEDETYTVRVLAFTSVG--DGP-- 501
Query 607 TFTTPKFAQGEIEAIVVPV 625
+ P + + P+
Sbjct 502 -LSDPIQVKTQQGVPGQPM 519
Score = 135 bits (339), Expect = 6e-31, Method: Composition-based stats.
Identities = 73/468 (16%), Positives = 144/468 (31%), Gaps = 79/468 (17%)
Query 200 AENALGKVTSDHINF-----DPVYKVKP-----------NPPHNLSVINSEELSSILKLT 243
A N+ G S N V +V P P N+++ S + +
Sbjct 208 ASNSAGVRYSSPANLYVRELREVRRVAPRFSILPVSHEIMPGGNVNITCVAVGSPMPYVK 267
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
W + P +D R+ + D+K Y C+
Sbjct 268 WMQGAED--------------------LTPEDDMPVGRNVLELTDVKDSANYT----CVA 303
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
G + + + + P ++ + W + P +
Sbjct 304 MSSLGVI-EAVAQITVKSLPKAPGTP--------VVTETTATSITITWDSGNPD----PV 350
Query 364 LDYEVTLTRWKSHL-----QNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA--VLTI 416
Y + ++ T + N Y ++ N +G+ + V+T
Sbjct 351 SYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTR 410
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQE 473
A+ P + ++W P E ++ Y + + + D+ +++WQ+
Sbjct 411 TGEQAPASAPRNVQGRMLSSTTMIIQWEEPVEPNGQIRGYRVYYTMEPDQ--PVSNWQKH 468
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGK 532
+ G+L E + Y + V + G G + I+ +Q P + R + +
Sbjct 469 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNFRAEAKTE 528
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
VL W + I Y + ++ T +T+ L +T Y+ R+
Sbjct 529 TSIVLSWSPPRQE----IIVKYELLFKEGDHGREVPRNFEPTTSFTVEGLKPNTEYVFRL 584
Query 593 AAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLF 639
AA + G G PE T + ++P + T VL
Sbjct 585 AARSALGLGAFTPEVRERTLQS--------ILPKNFKVKMVTKTSVLL 624
Score = 106 bits (263), Expect = 8e-22, Method: Composition-based stats.
Identities = 67/325 (21%), Positives = 110/325 (34%), Gaps = 35/325 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAKRDTP 179
P P+N+ + M +W+ G+ +T++ + +
Sbjct 416 PASAPRNVQGRMLSSTTMIIQWEEPVEPNGQIRGYRVYYTMEPDQPVSNWQ---KHNVDD 472
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSS 238
+ T S + V V A ++G SD I V P P N E S
Sbjct 473 SLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGV-PGQPMNFRAEAKTETS- 530
Query 239 ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ L+W+ P + II+KY + ++ D +SFTV+ LKP TEYVFR
Sbjct 531 -IVLSWSPPRQE--IIVKYELLFKEGDHGR----EVPRNFEPTTSFTVEGLKPNTEYVFR 583
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+ G G + T E R S K +V L W+ P
Sbjct 584 LAARSALGLGAF----------TPEVRERTLQSILPKNFKVKMVTKTSVLLSWEF--PEN 631
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVR--NLVGKSDAAVLTI 416
N Y++ ++ KL NL + + + N +G V
Sbjct 632 YNSPTP-YKIQYNGL--NVDVDGRTTKKLITNLKPHTFYNFVLMNRGNSMGGLQQNVAAW 688
Query 417 PACDFQATHPVMDLKAFPKDNMLWV 441
A + + P + K N++ +
Sbjct 689 TAANMLSRKPEVTHKPDADGNVVVI 713
>sp|Q61330|CNTN2_MOUSE Contactin-2 OS=Mus musculus OX=10090 GN=Cntn2
PE=1 SV=2
Length=1040
Score = 186 bits (471), Expect = 4e-47, Method: Composition-based stats.
Identities = 66/384 (17%), Positives = 121/384 (32%), Gaps = 25/384 (7%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQI--PPEDTASTRSSFTVQDLKPFTE 294
+ ++L+W+ I KY +Q RT + W Q+ P + + V L P+ +
Sbjct 623 DTTVQLSWSRGFDNHSPIAKYTLQARTPPSGKWKQVRTNPVNIEGNAETAQVLGLMPWMD 682
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y FR+ G G S S + T E PS + + W +
Sbjct 683 YEFRVSASNILGTGEPSGPS--SRIRTKEAVPS----VAPSGLSGGGGAPGELTINWTPM 736
Query 355 PPFEANGKILDYEVTLTRWKSHLQ---NYTVNATKLTVNL-----TNDRYLATLTVRNLV 406
NG Y ++ R S T+ V + + N
Sbjct 737 SREYQNGDGFGYLLSFRRQGSSSWQTARVPGADTQYFVYSNDSIHPYTPFEVKIRSYNRR 796
Query 407 GKSDAAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
G ++ I A + P + + V W + + +L + + KA
Sbjct 797 GDGPESLTAIVYSAEEEPKVAPAKVWAKGSSSSEMNVSWEPVLQDMNGILLGYEIRYWKA 856
Query 465 PCITDW--QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSK 521
+ + + L + Y +TV G G S A + PP +
Sbjct 857 GDKEAAADRVRTAGLDSSARVTGLYPNTKYHVTVRAYNRAGTGPASPSADAMTMKPPPRR 916
Query 522 GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS 581
P + + L+WD + + Y + Y+ + +++ S +
Sbjct 917 PPGNISWTFSSSSLSLKWDPVVPLRNESTVTGYKMLYQNDLQPTPMLHLTS--KNWIEIP 974
Query 582 LTSD-TLYMVRMAAYTDEGGKDGP 604
+ D +V++ T GG P
Sbjct 975 VPEDIGHALVQIR-TTGPGGDGIP 997
Score = 105 bits (262), Expect = 8e-22, Method: Composition-based stats.
Identities = 57/425 (13%), Positives = 123/425 (29%), Gaps = 43/425 (10%)
Query 140 KKMRCEWDGGRETHLE-TNFTLKSEWATH----KFADCKAKRDTPTSCTVDYSTVYFVNI 194
++ W G + H +TL++ + + + +++
Sbjct 624 TTVQLSWSRGFDNHSPIAKYTLQARTPPSGKWKQVRTNPVNIEGNAETAQVLGLMPWMDY 683
Query 195 EVWVEAENALGKV-TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN--PSIKS 251
E V A N LG S + + P+ + L + WT ++
Sbjct 684 EFRVSASNILGTGEPSGPSSRIRTKEAVPSV-APSGLSGGGGAPGELTINWTPMSREYQN 742
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
Y + +R + +S+W + ++ + P+T + +IR G G S
Sbjct 743 GDGFGYLLSFRRQGSSSWQTARVPGADTQYFVYSNDSIHPYTPFEVKIRSYNRRGDGPES 802
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
A + E+ P AP+ + + + + W+ + + NG +L YE+
Sbjct 803 L---TAIVYSAEEEPKVAPAKVW----AKGSSSSEMNVSWEPV-LQDMNGILLGYEIRYW 854
Query 372 RWKSHLQNYT-------VNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQA 423
+ ++ ++T N +Y T+ N G A+
Sbjct 855 KAGDKEAAADRVRTAGLDSSARVTGLYPNTKYHVTVRAYNRAGTGPASPSADAMTMKPPP 914
Query 424 THPVMDLKAFPKDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
P ++ + L ++W + + + +L T
Sbjct 915 RRPPGNISWTFSSSSLSLKWDPVVPLRNESTVTGYKMLYQNDLQPTPML----------- 963
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
+L I V + G V + G ++E +
Sbjct 964 --HLTSKNWIEIPV----PEDIGHALVQIRTTGPGGDGIPAEVHIVRNGGTSMMVESSAV 1017
Query 543 PVDVQ 547
Sbjct 1018 RPAHP 1022
Score = 100 bits (248), Expect = 4e-20, Method: Composition-based stats.
Identities = 52/305 (17%), Positives = 90/305 (30%), Gaps = 30/305 (10%)
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR------- 395
G TVQL W F+ + I Y + S
Sbjct 622 GDTTVQLSWS--RGFDNHSPIAKYTLQARTPPSGKWKQVRTNPVNIEGNAETAQVLGLMP 679
Query 396 ---YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN---MLWVEWTTPRES 449
Y ++ N++G + + + +A V L + WT
Sbjct 680 WMDYEFRVSASNILGTGEPSGPSSRIRTKEAVPSVAPSGLSGGGGAPGELTINWTPMSRE 739
Query 450 VKKYILEWCVLSDKAPCITDWQ--QEDGTVHRTYLRGN--LAESKCYLITVTPVYADGPG 505
+ +LS + + WQ + G + ++ N + + + + G G
Sbjct 740 YQNGDGFGYLLSFRRQGSSSWQTARVPGADTQYFVYSNDSIHPYTPFEVKIRSYNRRGDG 799
Query 506 SPE-SIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
+ Y + P P V K +E + W+ + + NG + Y I Y
Sbjct 800 PESLTAIVYSAEEEPKVAPAKVWAKGSSSSEMNVSWEPV-LQDMNGILLGYEIRYWKAGD 858
Query 564 NE---TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTT----PKFAQ 615
E V + ++ L +T Y V + AY G P T P+
Sbjct 859 KEAAADRVRTAGLDSSARVTGLYPNTKYHVTVRAYNRAGTGPASPSADAMTMKPPPRRPP 918
Query 616 GEIEA 620
G I
Sbjct 919 GNISW 923
>sp|Q02246|CNTN2_HUMAN Contactin-2 OS=Homo sapiens OX=9606 GN=CNTN2
PE=1 SV=1
Length=1040
Score = 186 bits (471), Expect = 5e-47, Method: Composition-based stats.
Identities = 65/385 (17%), Positives = 122/385 (32%), Gaps = 27/385 (7%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQI--PPEDTASTRSSFTVQDLKPFTE 294
+ ++L+W+ I KY +Q RT A W Q+ P + + V L P+ +
Sbjct 621 DTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNAETAQVLGLTPWMD 680
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y FR+ G G S S + T E PS + + W +
Sbjct 681 YEFRVIASNILGTGEPSGPSSKIR--TREAAPS----VAPSGLSGGGGAPGELIVNWTPM 734
Query 355 PPFEANGKILDYEVTLTR-WKSHLQNYTVNATKLTVNL-------TNDRYLATLTVRNLV 406
NG Y ++ R +H Q V + + + N
Sbjct 735 SREYQNGDGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNRR 794
Query 407 GKSDAAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD-- 462
G ++ + A + P + + V W ++ + +L + +
Sbjct 795 GDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQDMNGILLGYEIRYWKA 854
Query 463 -KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPS 520
D + G + G L + Y +TV G G S A + PP
Sbjct 855 GDKEAAADRVRTAGLDTSARVSG-LHPNTKYHVTVRAYNRAGTGPASPSANATTMKPPPR 913
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLS 580
+ P + + ++WD + + Y + Y+ + +++ +
Sbjct 914 RPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKMLYQNDLHLTPTLHLTG--KNWIEI 971
Query 581 SLTSD-TLYMVRMAAYTDEGGKDGP 604
+ D +V++ T GG P
Sbjct 972 PVPEDIGHALVQIR-TTGPGGDGIP 995
Score = 103 bits (257), Expect = 3e-21, Method: Composition-based stats.
Identities = 74/467 (16%), Positives = 148/467 (32%), Gaps = 50/467 (11%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIV--WKTNHFTI----PKEQYTIINR 84
++P S + L N T C H + W + F I P Y R
Sbjct 513 LAPSSADINLGDNLTLQC-------HASHDPTMDLTFTWTLDDFPIDFDKPGGHYR---R 562
Query 85 TASSVTFTDIASLNIQ------LTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNE 138
T T D+ LN Q TC T + ++ G P + + +
Sbjct 563 TNVKETIGDLTILNAQLRHGGKYTCMAQTV-VDSASKEATVLVRGPPGPPGGVVVRDIGD 621
Query 139 GKKMRCEWDGGRETHLE-TNFTLKSEWAT----HKFADCKAKRDTPTSCTVDYSTVYFVN 193
++ W G + H +TL++ + A + +++
Sbjct 622 -TTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNAETAQVLGLTPWMD 680
Query 194 IEVWVEAENALGKV-TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN--PSIK 250
E V A N LG S + + P+ + L + WT +
Sbjct 681 YEFRVIASNILGTGEPSGPSSKIRTREAAPSV-APSGLSGGGGAPGELIVNWTPMSREYQ 739
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
+ Y + +R + ++ W + ++ + ++P+T + +IR G G
Sbjct 740 NGDGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNRRGDGPE 799
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S A + E+ P AP+ + S + + + W+ + + NG +L YE+
Sbjct 800 SL---TALVYSAEEEPRVAPTKVWAKGVSSS----EMNVTWEPV-QQDMNGILLGYEIRY 851
Query 371 TRWKSHLQNYT-------VNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQ 422
+ + +++ N +Y T+ N G A+
Sbjct 852 WKAGDKEAAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPASPSANATTMKPP 911
Query 423 ATHPVMDLKAFPKDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCIT 468
P ++ + L ++W + + + +L +T
Sbjct 912 PRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKMLYQNDLHLT 958
Score = 103 bits (255), Expect = 5e-21, Method: Composition-based stats.
Identities = 58/305 (19%), Positives = 93/305 (30%), Gaps = 30/305 (10%)
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR------- 395
G T+QL W F+ + I Y + +
Sbjct 620 GDTTIQLSWS--RGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIEGNAETAQVLGLTP 677
Query 396 ---YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN---MLWVEWTTPRES 449
Y + N++G + + + +A V L V WT
Sbjct 678 WMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPMSRE 737
Query 450 VKKYILEWCVLSDKAPCITDWQ--QEDGTVHRTYLRGN--LAESKCYLITVTPVYADGPG 505
+ +LS + T WQ + G + ++ N + + + + G G
Sbjct 738 YQNGDGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNRRGDG 797
Query 506 SPE-SIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
+ Y + P PT V K V +E + W+ + D+ NG + Y I Y
Sbjct 798 PESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQDM-NGILLGYEIRYWKAGD 856
Query 564 NE---TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTT----PKFAQ 615
E V T +S L +T Y V + AY G P TT P+
Sbjct 857 KEAAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPP 916
Query 616 GEIEA 620
G I
Sbjct 917 GNISW 921
>sp|Q08501|PRLR_MOUSE Prolactin receptor OS=Mus musculus OX=10090
GN=Prlr PE=1 SV=1
Length=608
Score = 181 bits (459), Expect = 6e-47, Method: Composition-based stats.
Identities = 61/223 (27%), Positives = 95/223 (43%), Gaps = 15/223 (7%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKF-ADCK-AKRDTPTSC 182
PP KP+ C + + C W+ G + L TN++L K +C K P SC
Sbjct 22 PPGKPEIHKCRSPDKETFTCWWNPGSDGGLPTNYSLTYSKEGEKNTYECPDYKTSGPNSC 81
Query 183 TVDYSTVYFVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEELSSI 239
+ V A N +G TSD + D Y V+P PP NL+ V ++ +
Sbjct 82 FFSKQYTSIWKIYIITVNATNEMGSSTSDPLYVDVTYIVEPEPPRNLTLEVKQLKDKKTY 141
Query 240 LKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
L + W P+I V ++Y I+ ++++A W ++ F V DL P +Y
Sbjct 142 LWVKWLPPTITDVKTGWFTMEYEIRLKSEEADEWEI----HFTGHQTQFKVFDLYPGQKY 197
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+ + RC + GYWS W +E S D K + W +
Sbjct 198 LVQTRCKPD--HGYWSRWGQEKSIEIPNDFTLKDTTVWIIVAV 238
Score = 52.6 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 48/294 (16%), Positives = 90/294 (31%), Gaps = 14/294 (5%)
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR--ESVKKYILEWCVLSDKAPCITDW 470
+++ P + P W Y L + +K
Sbjct 13 SISLLNGQSPPGKPEIHKCRSPDKETFTCWWNPGSDGGLPTNYSLTYSKEGEKNTYECPD 72
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-----TV 525
+ G + + + K Y+ITV G + + + + + P V
Sbjct 73 YKTSGPNSCFFSKQYTSIWKIYIITVNATNEMGSSTSDPLYVDVTYIVEPEPPRNLTLEV 132
Query 526 RTKKVGKNEAVLEWDQLP-VDVQNG-FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLT 583
+ K K ++W DV+ G F Y I ++ +E ++ T++ + L
Sbjct 133 KQLKDKKTYLWVKWLPPTITDVKTGWFTMEYEIRLKSEEADEWEIHFTGHQTQFKVFDLY 192
Query 584 SDTLYMVRMAAYTDEGGKD--GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCF 641
Y+V+ D G G E + P + + + V + + L+ V
Sbjct 193 PGQKYLVQTRCKPDHGYWSRWGQEKSIEIPNDFTLKDTTVWIIVAVLSAVICLIMVWAVA 252
Query 642 NKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVE 695
K + I+P VP P I + H + +F S E
Sbjct 253 LKGYSMMTCIFPPVPGP---KIKGFDTHLLEKGKSEELLSALGCQDFPPTSDCE 303
Score = 47.5 bits (111), Expect = 5e-04, Method: Composition-based stats.
Identities = 30/195 (15%), Positives = 54/195 (28%), Gaps = 23/195 (12%)
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ------NYTVN 383
P +I + T W P G +Y +T ++ +
Sbjct 22 PPGKPEIHKCRSPDKETFTCWW---NPGSDGGLPTNYSLTYSKEGEKNTYECPDYKTSGP 78
Query 384 ATKLTVNLTNDR---YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF-----PK 435
+ Y+ T+ N +G S + L + P +L K
Sbjct 79 NSCFFSKQYTSIWKIYIITVNATNEMGSSTSDPLYVDVTYIVEPEPPRNLTLEVKQLKDK 138
Query 436 DNMLWVEWTTPRESVKKYILEWCVLSD----KAPCITDWQQEDGTVHRTYLRGNLAESKC 491
LWV+W P + W + K+ +W+ + +L +
Sbjct 139 KTYLWVKWLPPT--ITDVKTGWFTMEYEIRLKSEEADEWEIHFTGHQTQFKVFDLYPGQK 196
Query 492 YLITVTPVYADGPGS 506
YL+ G S
Sbjct 197 YLVQTRCKPDHGYWS 211
>sp|B8VIW9|FP_ACRMI Fibronectin type III domain-containing protein
OS=Acropora millepora OX=45264 PE=1 SV=1
Length=1280
Score = 186 bits (471), Expect = 7e-47, Method: Composition-based stats.
Identities = 116/570 (20%), Positives = 188/570 (33%), Gaps = 48/570 (8%)
Query 69 TNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEK 128
N +TI ++ +I + S + N G VY T I
Sbjct 484 GNGYTIEEDGTLVITKVERSQHAGKFSCYAKNFLGNATAEG--TATVYDRTRIV----RG 537
Query 129 PKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYST 188
P +LS +RCE ++ LE ++T K + AT ++ T+ T
Sbjct 538 PSDLSVNEGTRVDLRCE--AVADSSLELHYTWKRDDATIEYNRRVQWLKDQNVLTIADLT 595
Query 189 VYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
V I V A K + + P PP NL +++SE + L+W
Sbjct 596 VEDAGIYTCV-AYTPQPKYSEAKASAIVNIAGAPFPPTNL-MLSSECQNRNTTLSWVTGE 653
Query 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
+ IL + I+ +++ A + Q+ T +S + L + FRIR + G
Sbjct 654 SNNASILYFLIERKSQYADDFWQVIANVTNPNATSHPLVKLAGNADLAFRIRAVNRFG-- 711
Query 309 YWSDWSEEASG--ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
S SE T P K P + + + + W + E NG L Y
Sbjct 712 -PSRPSEPTGSFCRTIRAVPEKWPDNFRGV----PGKAEELTIAWTAMRRVEWNGPGLYY 766
Query 367 EVTLTRWKSH------LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT--IPA 418
++ R S + + ++ + ++ + N VG+ + L
Sbjct 767 KLWYRRVNSGDALVEVRREASSDSFVVPDAGYYRQWEFQIQAINEVGEGPKSPLVKQFSG 826
Query 419 CDFQATHPVMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKA--------PCI 467
D P + + W R SV Y + + S + P
Sbjct 827 QDPPTGKPEDVTVGTITARSVELSWKKVTFTRGSVDGYRIYFWGESRVSAKRRRRAIPGY 886
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVR 526
G Y L Y +T + G G + + A +A P V+
Sbjct 887 ASVTNVTGVNTERYTVTGLKPYTNYKFVITAYNSGGNGPESDQVAADTDEAEPGPPSDVQ 946
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEY-----TLS 580
V ++ W P NG I NY + T G++ T V V+ T L
Sbjct 947 VF-VFAKYILVTWQ--PPSEPNGVITNYRVGTETYTGSQPTDVTVNMEETGVEARRKLLR 1003
Query 581 SLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
L +T Y+V M A T +G T T
Sbjct 1004 DLVPETNYVVEMQAATSKGWGTSFRKTEKT 1033
Score = 93.8 bits (231), Expect = 4e-18, Method: Composition-based stats.
Identities = 54/332 (16%), Positives = 98/332 (30%), Gaps = 36/332 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNF-------TLKSEWATHKFADC 172
P KP++++ + + W G F + A +A
Sbjct 830 PTGKPEDVTVGTITARSVELSWKKVTFTRGSVDGYRIYFWGESRVSAKRRRRAIPGYASV 889
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
T + N + + A N+ G + +P PP ++ V
Sbjct 890 TNVTGVNTERYTVTGLKPYTNYKFVITAYNSGGNGPESDQVAADTDEAEPGPPSDVQVF- 948
Query 233 SEELSSILKLTWTNPSIKSVIILKYNI--QYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + +TW PS + +I Y + + T T + E+T ++DL
Sbjct 949 --VFAKYILVTWQPPSEPNGVITNYRVGTETYTGSQPTDVTVNMEETGVEARRKLLRDLV 1006
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
P T YV ++ G G +E+ +P K V++
Sbjct 1007 PETNYVVEMQAATSKGWGTSFRKTEKTVAWAAPAKPEKP--------IVEGTAVDEVRVD 1058
Query 351 WKTLPPFEANGKILDYEVTLTRW-------KSHLQNYTVNATKLTVNLTNDRYLATLTVR 403
+K G D+ V + + ++ + + NL + Y R
Sbjct 1059 YKF---GLGGGYTHDFLVMFRKKIEGQEFQNTSWVDHFQQQSIIIGNLDPELYQFKTVAR 1115
Query 404 NLVGKSDAAVLTIPACDFQATHPVMDLKAFPK 435
N S PA D P + K
Sbjct 1116 ND-YPSQENPQESPASDITEARPRPGISNVGK 1146
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 47/320 (15%), Positives = 89/320 (28%), Gaps = 28/320 (9%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
PE V + + K+ V+ I + K + I AS T
Sbjct 834 PEDVTVGTITARSVELSWKKVTFTRGSVDGYRIYFWGESRVSAKRRRRAIPGYASVTNVT 893
Query 93 DIASLNIQLTC-----------NILTFGQLEQNVYGITIISGLP-PEKPKNLSCIVNEGK 140
+ + +T G + + P P ++ V K
Sbjct 894 GVNTERYTVTGLKPYTNYKFVITAYNSGGNGPESDQVAADTDEAEPGPPSDVQVFVF-AK 952
Query 141 KMRCEWDGGRET-HLETNFTLKSE-WATHKFADCK---AKRDTPTSCTVDYSTVYFVNIE 195
+ W E + TN+ + +E + + D + + V N
Sbjct 953 YILVTWQPPSEPNGVITNYRVGTETYTGSQPTDVTVNMEETGVEARRKLLRDLVPETNYV 1012
Query 196 VWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
V ++A + G TS V P P V + + + + L
Sbjct 1013 VEMQAATSKGWGTSFRKTEKTVAWAAPAKPEKPIVEGTAVDEVRVDYKFGLGGGYTHDFL 1072
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+ + + + + + S + +L P Y F+ + Y S +
Sbjct 1073 V-MFRKKIEGQEFQNTSWVDHF--QQQSIIIGNLDPE-LYQFKTVARND----YPSQENP 1124
Query 316 EASGIT--YEDRPSKAPSFW 333
+ S + E RP S
Sbjct 1125 QESPASDITEARPRPGISNV 1144
>sp|P28685|CNTN2_CHICK Contactin-2 OS=Gallus gallus OX=9031 GN=CNTN2
PE=1 SV=1
Length=1036
Score = 184 bits (467), Expect = 1e-46, Method: Composition-based stats.
Identities = 66/386 (17%), Positives = 127/386 (33%), Gaps = 28/386 (7%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQI--PPEDTASTRSSFTVQDLKPFTE 294
+ ++L+W+ I +Y+I+ RT ++ W Q+ P + + V +L P+ +
Sbjct 616 DTTVQLSWSRGFDNHSPIARYSIEARTLLSNKWKQMRTNPVNIEGNAETAQVVNLIPWMD 675
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y FR+ G G S S + T E P+ APS + + W
Sbjct 676 YEFRVLASNILGVGEPSLPSSKIR--TKEAAPTVAPSG----LGGGGGAPNELIINWTPT 729
Query 355 PPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN--------LTNDRYLATLTVRNLV 406
NG Y ++ + + +++ + + N
Sbjct 730 LRDYQNGDGFGYILSFRKKGTQGWLTARVPHAESLHYVYRNESIGPYTPFEVKIKAYNRK 789
Query 407 GKSDAAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTP-----RESVKKYILEWCV 459
G+ ++ I A + P + + V W + Y + +
Sbjct 790 GEGPESLTAIVYSAEEEPKVAPFRVTAKAVLSSEMDVSWEPVEQGDMTGVLLGYEIRYWK 849
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-SIKAYLKQAP 518
DK D + G V ++ G L + Y ++V G G P S + P
Sbjct 850 DGDKEEAA-DRVRTAGLVTSAHVTG-LNPNTKYHVSVRAYNRAGAGPPSPSTNITTTKPP 907
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
P + P + + + ++WD + + Y + YR + +S +
Sbjct 908 PRRPPGNISWTLTGSTVTIKWDPVVAQADESAVTGYKMLYRQ-DSHSAPTLYLASKSRID 966
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGP 604
+ T V++ T GG P
Sbjct 967 IPVPEDFTHAFVQIR-VTGPGGDGTP 991
Score = 109 bits (271), Expect = 6e-23, Method: Composition-based stats.
Identities = 59/292 (20%), Positives = 100/292 (34%), Gaps = 27/292 (9%)
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVT----LTRWKSHLQNYTVNA-----TKLTVNLTN 393
G TVQL W F+ + I Y + L+ ++ VN T VNL
Sbjct 615 GDTTVQLSWS--RGFDNHSPIARYSIEARTLLSNKWKQMRTNPVNIEGNAETAQVVNLIP 672
Query 394 D-RYLATLTVRNLVGKSDAAVLTIPACDFQATH---PVMDLKAFPKDNMLWVEWTT---- 445
Y + N++G + ++ + +A P N L + WT
Sbjct 673 WMDYEFRVLASNILGVGEPSLPSSKIRTKEAAPTVAPSGLGGGGGAPNELIINWTPTLRD 732
Query 446 -PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
YIL + + +T ++H Y ++ + + + G
Sbjct 733 YQNGDGFGYILSFRKKGTQG-WLTARVPHAESLHYVYRNESIGPYTPFEVKIKAYNRKGE 791
Query 505 GSPE-SIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTI 561
G + Y + P P V K V +E + W+ + G + Y I +++
Sbjct 792 GPESLTAIVYSAEEEPKVAPFRVTAKAVLSSEMDVSWEPVEQGDMTGVLLGYEIRYWKDG 851
Query 562 IGNETAVNVDSS--HTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTT 610
E A V ++ T ++ L +T Y V + AY G G P TT
Sbjct 852 DKEEAADRVRTAGLVTSAHVTGLNPNTKYHVSVRAYNRAGAGPPSPSTNITT 903
Score = 104 bits (258), Expect = 2e-21, Method: Composition-based stats.
Identities = 49/348 (14%), Positives = 105/348 (30%), Gaps = 27/348 (8%)
Query 140 KKMRCEWDGGRETHLE-TNFTLKSEWATH----KFADCKAKRDTPTSCTVDYSTVYFVNI 194
++ W G + H +++++ + + + + +++
Sbjct 617 TTVQLSWSRGFDNHSPIARYSIEARTLLSNKWKQMRTNPVNIEGNAETAQVVNLIPWMDY 676
Query 195 EVWVEAENALGKVTSD--HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV 252
E V A N LG P L I+ T T ++
Sbjct 677 EFRVLASNILGVGEPSLPSSKIRTKEAAPTVAPSGLGGGGGAPNELIINWTPTLRDYQNG 736
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
Y + +R K W S + + + P+T + +I+ G+G S
Sbjct 737 DGFGYILSFRKKGTQGWLTARVPHAESLHYVYRNESIGPYTPFEVKIKAYNRKGEGPESL 796
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR 372
A + E+ P AP + + + W+ + + G +L YE+ +
Sbjct 797 ---TAIVYSAEEEPKVAP----FRVTAKAVLSSEMDVSWEPVEQGDMTGVLLGYEIRYWK 849
Query 373 WKSHLQNYT-------VNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQAT 424
+ V + +T N +Y ++ N G + I
Sbjct 850 DGDKEEAADRVRTAGLVTSAHVTGLNPNTKYHVSVRAYNRAGAGPPSPSTNITTTKPPPR 909
Query 425 HPVMDLKAFPKDNMLWVEWTTP-----RESVKKYILEWCVLSDKAPCI 467
P ++ + + ++W +V Y + + S AP +
Sbjct 910 RPPGNISWTLTGSTVTIKWDPVVAQADESAVTGYKMLYRQDSHSAPTL 957
Score = 93.0 bits (229), Expect = 7e-18, Method: Composition-based stats.
Identities = 66/376 (18%), Positives = 118/376 (31%), Gaps = 47/376 (13%)
Query 75 PKEQYTIINRTASSVTFTDIASLNIQLTCNI-------------LTFGQLEQNVYGITII 121
P +Y+I RT S + + + + + N F L N+ G+
Sbjct 632 PIARYSIEARTLLSNKWKQMRTNPVNIEGNAETAQVVNLIPWMDYEFRVLASNILGVG-E 690
Query 122 SGLPPEK-----------PKNLSCIVNEGKKMRCEWDGGRETHLETN---FTLKSEWATH 167
LP K P L ++ W + + + L
Sbjct 691 PSLPSSKIRTKEAAPTVAPSGLGGGGGAPNELIINWTPTLRDYQNGDGFGYILSFRKKGT 750
Query 168 KFADCKAKRDTPTSCTVDYSTVY---FVNIEVWVEAENALGKVTSDHINFDPVYKVKPN- 223
+ A+ S Y + EV ++A N G+ + +P
Sbjct 751 Q-GWLTARVPHAESLHYVYRNESIGPYTPFEVKIKAYNRKGEGPESLTAIVYSAEEEPKV 809
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKS--VIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P ++ LSS + ++W ++L Y I+Y KD TA
Sbjct 810 APFRVTAKAV--LSSEMDVSWEPVEQGDMTGVLLGYEIRY-WKDGDKEEAADRVRTAGLV 866
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+S V L P T+Y +R G G S ++ IT +K P + S T
Sbjct 867 TSAHVTGLNPNTKYHVSVRAYNRAGAGPPS----PSTNITT----TKPPPRRPPGNISWT 918
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTR-WKSHLQNYTVNATKLTVNLTNDRYLATL 400
TV + W + + Y++ + S Y + +++ + + D A +
Sbjct 919 LTGSTVTIKWDPVVAQADESAVTGYKMLYRQDSHSAPTLYLASKSRIDIPVPEDFTHAFV 978
Query 401 TVRNLVGKSDAAVLTI 416
+R D +
Sbjct 979 QIRVTGPGGDGTPAEV 994
>sp|P16471|PRLR_HUMAN Prolactin receptor OS=Homo sapiens OX=9606
GN=PRLR PE=1 SV=1
Length=622
Score = 180 bits (455), Expect = 2e-46, Method: Composition-based stats.
Identities = 60/239 (25%), Positives = 95/239 (40%), Gaps = 21/239 (9%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKS----EWATHKFADCKAKRDTP 179
LPP KP+ C + C W G + L TN++L E H+ D P
Sbjct 26 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI--TGGP 83
Query 180 TSCTVDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPP--HNLSVINSEEL 236
SC T + + V A N +G SD + D Y V+P+PP + V E+
Sbjct 84 NSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDR 143
Query 237 SSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
L + W+ P++ + L Y I+ + + A+ W A ++ F + L P
Sbjct 144 KPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEI----HFAGQQTEFKILSLHPG 199
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
+Y+ ++RC + GYWS WS D + W I + + +VW
Sbjct 200 QKYLVQVRCKPD--HGYWSAWSPATFIQIPSDFTMNDTTVW--ISVAVLSAVICLIIVW 254
Score = 47.9 bits (112), Expect = 4e-04, Method: Composition-based stats.
Identities = 47/289 (16%), Positives = 87/289 (30%), Gaps = 18/289 (6%)
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGP---TVRTKKVGKNE--AVLEWDQLPVDV 546
Y++ V G + + + P V K+ + ++W +
Sbjct 99 YIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLID 158
Query 547 QNG--FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD-- 602
F Y I + E ++ TE+ + SL Y+V++ D G
Sbjct 159 LKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAW 218
Query 603 GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSH 662
P P + + V + + L+ V K + I+P VP P
Sbjct 219 SPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGP---K 275
Query 663 IAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPE-DLKSLDLFKKEKINT 721
I + H + +F S E + + + + L ++ +
Sbjct 276 IKGFDAHLLEKGKSEELLSALGCQDFPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPS 335
Query 722 EGHSSGI----GGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSG 766
+G S S PS+ S++ E Q ST V+
Sbjct 336 QGMKPTYLDPDTDSGRGSCDSPSL-LSEKCEEPQANPSTFYDPEVIEKP 383
Score = 43.7 bits (101), Expect = 0.007, Method: Composition-based stats.
Identities = 35/206 (17%), Positives = 61/206 (30%), Gaps = 27/206 (13%)
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL-----------Q 378
P +I + T W+ P G +Y +T R L
Sbjct 27 PPGKPEIFKCRSPNKETFTCWWR---PGTDGGLPTNYSLTYHREGETLMHECPDYITGGP 83
Query 379 NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
N + T Y+ + N +G S + L + P ++L K
Sbjct 84 NSCHFGKQYTSMWRT--YIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPE 141
Query 439 -----LWVEWTTPRESVKKYILEWCVLSD----KAPCITDWQQEDGTVHRTYLRGNLAES 489
LW++W+ P + W L K +W+ + +L
Sbjct 142 DRKPYLWIKWSPPT--LIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHPG 199
Query 490 KCYLITVTPVYADGPGSPESIKAYLK 515
+ YL+ V G S S +++
Sbjct 200 QKYLVQVRCKPDHGYWSAWSPATFIQ 225
>sp|P22063|CNTN2_RAT Contactin-2 OS=Rattus norvegicus OX=10116
GN=Cntn2 PE=1 SV=1
Length=1040
Score = 183 bits (465), Expect = 2e-46, Method: Composition-based stats.
Identities = 68/385 (18%), Positives = 123/385 (32%), Gaps = 27/385 (7%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQI--PPEDTASTRSSFTVQDLKPFTE 294
+ ++L+W+ I KY +Q RT + W Q+ P + + V L P+ +
Sbjct 623 DTTVQLSWSRGFDNHSPIAKYTLQARTPPSGKWKQVRTNPVNIEGNAETAQVLGLMPWMD 682
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y FR+ G G S S + T E PS + + W +
Sbjct 683 YEFRVSASNILGTGEPSGPSSKIR--TKEAVPS----VAPSGLSGGGGAPGELIINWTPV 736
Query 355 PPFEANGKILDYEVTLTR-WKSHLQNYTVNATKLTVNL-------TNDRYLATLTVRNLV 406
NG Y ++ R S Q V + + + N
Sbjct 737 SREYQNGDGFGYLLSFRRQGSSSWQTARVPGADAQYFVYGNDSIQPYTPFEVKIRSYNRR 796
Query 407 GKSDAAVLTI--PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
G ++ + A + P + + V W + + +L + + KA
Sbjct 797 GDGPESLTALVYSAEEEPRVAPAKVWAKGSSSSEMNVSWEPVLQDMNGILLGYEIRYWKA 856
Query 465 ---PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPS 520
D + G + G L + Y +TV G G S A + PP
Sbjct 857 GDNEAAADRVRTAGLDTSARVTG-LNPNTKYHVTVRAYNRAGTGPASPSADAMTVKPPPR 915
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLS 580
+ P + + L+WD + + Y + Y+ + +++ S +
Sbjct 916 RPPGNISWTFSSSSLSLKWDPVVPLRNESTVTGYKMLYQNDLHPTPTLHLTS--KNWIEI 973
Query 581 SLTSD-TLYMVRMAAYTDEGGKDGP 604
+ D +V++ T GG P
Sbjct 974 PVPEDIGHALVQIR-TTGPGGDGIP 997
Score = 106 bits (263), Expect = 7e-22, Method: Composition-based stats.
Identities = 55/305 (18%), Positives = 92/305 (30%), Gaps = 30/305 (10%)
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR------- 395
G TVQL W F+ + I Y + S
Sbjct 622 GDTTVQLSWS--RGFDNHSPIAKYTLQARTPPSGKWKQVRTNPVNIEGNAETAQVLGLMP 679
Query 396 ---YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN---MLWVEWTTPRES 449
Y ++ N++G + + + +A V L + WT
Sbjct 680 WMDYEFRVSASNILGTGEPSGPSSKIRTKEAVPSVAPSGLSGGGGAPGELIINWTPVSRE 739
Query 450 VKKYILEWCVLSDKAPCITDWQ--QEDGTVHRTYLRGN--LAESKCYLITVTPVYADGPG 505
+ +LS + + WQ + G + ++ GN + + + + G G
Sbjct 740 YQNGDGFGYLLSFRRQGSSSWQTARVPGADAQYFVYGNDSIQPYTPFEVKIRSYNRRGDG 799
Query 506 SPE-SIKAYLKQAPPSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
+ Y + P P V K +E + W+ + + NG + Y I Y
Sbjct 800 PESLTALVYSAEEEPRVAPAKVWAKGSSSSEMNVSWEPV-LQDMNGILLGYEIRYWKAGD 858
Query 564 NE---TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTT----PKFAQ 615
NE V T ++ L +T Y V + AY G P T P+
Sbjct 859 NEAAADRVRTAGLDTSARVTGLNPNTKYHVTVRAYNRAGTGPASPSADAMTVKPPPRRPP 918
Query 616 GEIEA 620
G I
Sbjct 919 GNISW 923
Score = 103 bits (257), Expect = 3e-21, Method: Composition-based stats.
Identities = 49/342 (14%), Positives = 109/342 (32%), Gaps = 26/342 (8%)
Query 140 KKMRCEWDGGRETHLE-TNFTLKSEWATH----KFADCKAKRDTPTSCTVDYSTVYFVNI 194
++ W G + H +TL++ + + + +++
Sbjct 624 TTVQLSWSRGFDNHSPIAKYTLQARTPPSGKWKQVRTNPVNIEGNAETAQVLGLMPWMDY 683
Query 195 EVWVEAENALGKV-TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN--PSIKS 251
E V A N LG S + + P+ + L + WT ++
Sbjct 684 EFRVSASNILGTGEPSGPSSKIRTKEAVPSV-APSGLSGGGGAPGELIINWTPVSREYQN 742
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
Y + +R + +S+W + + ++P+T + +IR G G S
Sbjct 743 GDGFGYLLSFRRQGSSSWQTARVPGADAQYFVYGNDSIQPYTPFEVKIRSYNRRGDGPES 802
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
A + E+ P AP+ + + + + W+ + + NG +L YE+
Sbjct 803 L---TALVYSAEEEPRVAPAKVW----AKGSSSSEMNVSWEPV-LQDMNGILLGYEIRYW 854
Query 372 RWKSHLQNYT-------VNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQA 423
+ + + ++T N +Y T+ N G A+
Sbjct 855 KAGDNEAAADRVRTAGLDTSARVTGLNPNTKYHVTVRAYNRAGTGPASPSADAMTVKPPP 914
Query 424 THPVMDLKAFPKDNMLWVEWTT-PRESVKKYILEWCVLSDKA 464
P ++ + L ++W + + + +L
Sbjct 915 RRPPGNISWTFSSSSLSLKWDPVVPLRNESTVTGYKMLYQND 956
>sp|Q2EY13|PRTGB_DANRE Protogenin B (Fragment) OS=Danio rerio
OX=7955 GN=prtgb PE=2 SV=1
Length=1069
Score = 184 bits (466), Expect = 2e-46, Method: Composition-based stats.
Identities = 97/617 (16%), Positives = 193/617 (31%), Gaps = 54/617 (9%)
Query 16 LTTESTGELLDPCGYIS-PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTI 74
TT + + P + PES C I W N I
Sbjct 300 YTTAAGNVTVLPPSLVEKPESQTRPRAGTARFSC-------QAEGTPTPQITWFKNGEVI 352
Query 75 PKEQYTIINRTASSVTFTDIASLNIQLTCNILTF-GQLEQNVYGITIISGLPPEKPKNLS 133
T + +T I + C G + I + S P P+N+
Sbjct 353 RTNGRTKMYNNKLVIT-QIIPEDDAFYQCLAENSQGSVVSTSRLIVVQSENRPSAPRNIH 411
Query 134 CIVNEGKKMRCEWDGGRETHLET-NFTLKS-EWATHKFADCKAKRDTPTSCTVDYSTVYF 191
+ W+ + + +++ + + +A T+ +
Sbjct 412 AETISSSAILLAWERPQYNADKVIAYSIHYMKSEGLNNEEYQAVIGNDTTSHIVDDLEPA 471
Query 192 VNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN--PS 248
N ++ A A+G S+ + + V P + + + + ++W P
Sbjct 472 RNYTFYIVAYMAMGASRMSEQVTRHTLEDVPLRTPE---LSLTSRSPTDILVSWQPLPPK 528
Query 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
+ + Y + YRT + + + + + +QDL+P T Y+ R+ G
Sbjct 529 LSRGRVSAYRLSYRTATDEQVNSVELPVSGENGTQYLLQDLQPDTIYLIRMSVSTRVGWS 588
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
S WS + T AP+ + +V + W P ++ I +++
Sbjct 589 QPSAWSSHRTPKTSSATVPPAPNLELEPLNCT-----SVSVRW---FPAASDVLIQGFKL 640
Query 369 TLTRWKSHLQNYT-----VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI------- 416
+ + T + +T +Y + + G A T+
Sbjct 641 SFHPDGQSEDSITQLPPQDHQHTITALNPRVKYHVKVLAFSANGDGYQAHQTVNTPGCPS 700
Query 417 -PACDFQATHPVMDLKA-FPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQ 471
P A P A + + + W P + + + S +
Sbjct 701 TPNRRLAALPPPDHTHAKANSSSAVHLSWGRPAFSSGKPVTFSVRYGPASPSEASSVRYI 760
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPV--YADGPGSPESIKAYLKQAPPSKGPTVRTKK 529
Q T +T + L + Y V P S + L +AP S +V+
Sbjct 761 Q---TSEQTVMVTGLQPNTRYEFAVRLHMDQMSSPWSATVYQRTLLEAPMSPPESVKVTL 817
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII----GNETAVNVDSSHTEYTLSSLTSD 585
+ + A++ W Q + N + +YT+ Y + G + + ++T L L S
Sbjct 818 IEADTALVCWKQ--PNQPNLSVTHYTVLYASQSSWLAGEWQVLQREGTNTMALLEKLESG 875
Query 586 TLYMVRMAAYTDEGGKD 602
+Y+V+++A G
Sbjct 876 NVYLVKISASNLAGDGP 892
Score = 104 bits (259), Expect = 2e-21, Method: Composition-based stats.
Identities = 48/307 (16%), Positives = 100/307 (33%), Gaps = 29/307 (9%)
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL--TRWKSHLQNY 380
E+RPS + + T + L W+ P K++ Y + + ++ +
Sbjct 401 ENRPSAP-----RNIHAETISSSAILLAWE--RPQYNADKVIAYSIHYMKSEGLNNEEYQ 453
Query 381 TVNATKLTVNLTND-----RYLATLTVRNLVGKS--DAAVLTIPACDFQATHPVMDLKAF 433
V T ++ +D Y + +G S V D P + L +
Sbjct 454 AVIGNDTTSHIVDDLEPARNYTFYIVAYMAMGASRMSEQVTRHTLEDVPLRTPELSLTS- 512
Query 434 PKDNMLWVEWTT-PRESVKKYILEWCVLSD---KAPCITDWQQEDGTVHRTYLRGNLAES 489
+ V W P + + + + + + G YL +L
Sbjct 513 RSPTDILVSWQPLPPKLSRGRVSAYRLSYRTATDEQVNSVELPVSGENGTQYLLQDLQPD 572
Query 490 KCYLITVTPVYADGPGSPESIKA----YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
YLI ++ G P + + A P + + + + W D
Sbjct 573 TIYLIRMSVSTRVGWSQPSAWSSHRTPKTSSATVPPAPNLELEPLNCTSVSVRWFPAASD 632
Query 546 VQNGFIRNYTIFYRTIIGNETAVN-VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
V I+ + + + +E ++ + ++T+++L Y V++ A++ G
Sbjct 633 VL---IQGFKLSFHPDGQSEDSITQLPPQDHQHTITALNPRVKYHVKVLAFSANGDGYQA 689
Query 605 EFTFTTP 611
T TP
Sbjct 690 HQTVNTP 696
Score = 104 bits (258), Expect = 3e-21, Method: Composition-based stats.
Identities = 61/327 (19%), Positives = 97/327 (30%), Gaps = 30/327 (9%)
Query 121 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
+ +PP NL + W L F L S + D +
Sbjct 603 SATVPPAP--NLELEPLNCTSVSVRWFPAASDVLIQGFKL-SFHPDGQSEDSITQLPPQD 659
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFD-------PVYKVKPNPPHNLSVINS 233
+ V V V A +A G H + P ++ PP +
Sbjct 660 HQHTITALNPRVKYHVKVLAFSANGDGYQAHQTVNTPGCPSTPNRRLAALPPPD-HTHAK 718
Query 234 EELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
SS + L+W P+ S + ++++Y S S + T+ V L+P T
Sbjct 719 ANSSSAVHLSWGRPAFSSGKPVTFSVRYGPASPSEASSVRYIQTSEQT--VMVTGLQPNT 776
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
Y F +R + S WS T + P P T + WK
Sbjct 777 RYEFAVRLHMDQMS---SPWSATVYQRTLLEAPMSPPESVKV----TLIEADTALVCWKQ 829
Query 354 LPPFEANGKILDYEVTL--------TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNL 405
P + N + Y V W+ + T L + + YL ++ NL
Sbjct 830 --PNQPNLSVTHYTVLYASQSSWLAGEWQVLQREGTNTMALLEKLESGNVYLVKISASNL 887
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKA 432
G + A + H A
Sbjct 888 AGDGPFSNTVELAVKGKPHHGKNPRHA 914
>sp|O42414|NFASC_CHICK Neurofascin OS=Gallus gallus OX=9031 GN=NFASC
PE=1 SV=1
Length=1369
Score = 180 bits (457), Expect = 3e-45, Method: Composition-based stats.
Identities = 76/424 (18%), Positives = 136/424 (32%), Gaps = 55/424 (13%)
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
+ K +P+ P +L + + E S +KLTW + I Y +Q+ +
Sbjct 635 LRDLPKERPDRPRDLELSDLAERS--VKLTWIPGDDNNSPITDYIVQFEEDRFQPGTWHN 692
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
+S + L P+ Y FR+ + + G S SE T RP
Sbjct 693 HSRYPGNVNSALLS-LSPYVNYQFRVIAVNDVGSSLPSMPSE--RYQTSGARP------- 742
Query 334 YKIDPSHTQGYRT----VQLVWKTLPPFEANGKILDYEVTLTR------WKSHL---QNY 380
+I+P+ QG T +++ W L +A G L Y V R W + +
Sbjct 743 -EINPTGVQGAGTQKNNMEITWTPLNATQAYGPNLRYIVRWRRRDPRGSWYNETVKAPRH 801
Query 381 TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI--PACDFQATHPVMDLKAFPKDNM 438
V T + V Y + N G++ I D+ P
Sbjct 802 VVWNTPIYV-----PYEIKVQAENDFGRAPEPETYIGYSGEDYPKAAPTDVRIRVLNSTA 856
Query 439 LWVEWTTPR-ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY--------LRGNLAES 489
+ + WT ++++ + E+ + + + L
Sbjct 857 IALTWTRVHLDTIQGQLKEYRAYFWRDSSLLKNLWVSKKRQYVSFPGDRNRGIVSRLFPY 916
Query 490 KCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
Y + + G G +K + + PS +R ++ LEWD + N
Sbjct 917 SNYKLEMVVTNGRGDGPRSEVKEFPTPEGVPSSPRYLRIRQPNLESINLEWDH--PEHPN 974
Query 549 GFIRNYTIFYRT----------IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
G + Y + Y+ G N + T +T+ + Y + A T
Sbjct 975 GVLTGYNLRYQASCLSSPVNGSKTGRTLVENFSPNQTRFTVQRTDPISRYRFFLRARTQV 1034
Query 599 GGKD 602
G +
Sbjct 1035 GDGE 1038
Score = 106 bits (263), Expect = 8e-22, Method: Composition-based stats.
Identities = 82/556 (15%), Positives = 163/556 (29%), Gaps = 75/556 (13%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
PE VV+ S C +K V W + + + + +T
Sbjct 546 PEDQVVKRGSMPRLHCRVKHDPTLKLTVT-----WLKDDAPLYIGN--RMKKEDDGLTIY 598
Query 93 DIASLNIQ-LTCNI-LTFGQLEQNVYGITIIS------GLP---PEKPKNLSCIVNEGKK 141
+A + TC + Y + LP P++P++L +
Sbjct 599 GVAEKDQGDYTCVASTELDKDSAKAYLTVLAIPANRLRDLPKERPDRPRDLELSDLAERS 658
Query 142 MRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY-FVNIEVWVE 199
++ W G + + T++ ++ E + P + ++ +VN + V
Sbjct 659 VKLTWIPGDDNNSPITDYIVQFEEDRFQPGTWHNHSRYPGNVNSALLSLSPYVNYQFRVI 718
Query 200 AENALGKV-TSDHINFDPVYKVKPNPPHNLS-VINSEELSSILKLTWTN--PSIKSVIIL 255
A N +G S +P N + V + + +++TWT + L
Sbjct 719 AVNDVGSSLPSMPSERYQTSGARPE--INPTGVQGAGTQKNNMEITWTPLNATQAYGPNL 776
Query 256 KYNIQYRTKD-ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
+Y +++R +D +W + V + + Y +++ + G+
Sbjct 777 RYIVRWRRRDPRGSW-----YNETVKAPRHVVWNTPIYVPYEIKVQAENDFGRAPEP--- 828
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR-- 372
E G + ED P AP+ + L W + G++ +Y R
Sbjct 829 ETYIGYSGEDYPKAAPTDVRI----RVLNSTAIALTWTRVHLDTIQGQLKEYRAYFWRDS 884
Query 373 ------WKSHLQNY-----TVNATKLTVNLTNDRYLATLTVRNLVGKSD-AAVLTIPACD 420
W S + Y N ++ Y + V N G + V P +
Sbjct 885 SLLKNLWVSKKRQYVSFPGDRNRGIVSRLFPYSNYKLEMVVTNGRGDGPRSEVKEFPTPE 944
Query 421 FQATHPVMDLKAFPKDNMLWVEW---TTPRESVKKYILEW------CVLSDKAPCITDWQ 471
+ P P + +EW P + Y L + ++ T +
Sbjct 945 GVPSSPRYLRIRQPNLESINLEWDHPEHPNGVLTGYNLRYQASCLSSPVNGSKTGRTLVE 1004
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
R Y + G G + ++++P +
Sbjct 1005 NFSPNQTRF-TVQRTDPISRYRFFLRARTQVGDG-----EVIVEESPAL----LNEATPT 1054
Query 532 KNEAVLEWDQLPVDVQ 547
W P
Sbjct 1055 PAS---TWLPPPTTEL 1067
Score = 73.7 bits (179), Expect = 6e-12, Method: Composition-based stats.
Identities = 93/615 (15%), Positives = 173/615 (28%), Gaps = 94/615 (15%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTD 93
S +V + C+ V A I+W +P + + N ++ ++
Sbjct 272 SSQMVLRGVDLLLECI-------ASGVPAPDIMWYKKGGELPAGKTKLEN-FNKALRISN 323
Query 94 IASLNI-QLTCNILTFGQLEQNVYGITIISGLPP---EKPKNLSCIVNEGKKMRCE---- 145
++ + + C L ++ + I++ P ++P+NL E ++ C
Sbjct 324 VSEEDSGEYFC--LASNKMGSIRHTISVRVKAAPYWLDEPQNLILAPGEDGRLVCRANGN 381
Query 146 ------W--DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
W +G N + + T F D + C
Sbjct 382 PKPSIQWLVNGEPIEGSPPNPSREVAGDTIVFRDTQIGSSAVYQC--------------- 426
Query 198 VEAENALGKVTSDHINFDPVYKVKP--NPPHN--LSVINSEEL--------SSILKLTWT 245
A N G + ++ F V V P P N + VI S I L W
Sbjct 427 -NASNEHGYLLANA--FVSVLDVPPRILAPRNQLIKVIQYNRTRLDCPFFGSPIPTLRWF 483
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM--K 303
+++ Y+ + + + ++ E R+
Sbjct 484 KNGQGNMLDGGN---YKAHENGSLEMSMARKEDQGIYTCVATNILGKVEAQVRLEVKDPT 540
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
+G + S R P+ K+ + + + + E +G
Sbjct 541 RIVRGPEDQVVKRGSMPRLHCRVKHDPTL--KLTVTWLKDDAPLYI--GNRMKKEDDGLT 596
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA 423
+ Y V ++ + L D A LTV + +
Sbjct 597 I-YGVA-------EKDQGDYTCVASTELDKDSAKAYLTVL------AIPANRLRDLPKER 642
Query 424 THPVMDLKAFP-KDNMLWVEWTT---PRESVKKYILEWCVLSDKAPCITDWQQE---DGT 476
DL+ + + + W + YI++ + W G
Sbjct 643 PDRPRDLELSDLAERSVKLTWIPGDDNNSPITDYIVQ---FEEDRFQPGTWHNHSRYPGN 699
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPE--SIKAYLKQAPPSKGPT-VRTKKVGKN 533
V+ L L+ Y V V G P S + A P PT V+ KN
Sbjct 700 VNSALLS--LSPYVNYQFRVIAVNDVGSSLPSMPSERYQTSGARPEINPTGVQGAGTQKN 757
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
+ W L G Y + +R + N + + + Y +++
Sbjct 758 NMEITWTPLNATQAYGPNLRYIVRWRRRDPRGSWYNETVKAPRHVVWNTPIYVPYEIKVQ 817
Query 594 AYTDEGGKDGPEFTF 608
A D G PE
Sbjct 818 AENDFGRAPEPETYI 832
>sp|Q60847|COCA1_MOUSE Collagen alpha-1(XII) chain OS=Mus musculus
OX=10090 GN=Col12a1 PE=2 SV=3
Length=3120
Score = 178 bits (450), Expect = 4e-44, Method: Composition-based stats.
Identities = 87/490 (18%), Positives = 145/490 (30%), Gaps = 54/490 (11%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFT---LKSEWATHKFADCKAKRDTPTSCTV 184
P NL + R WD G T + + + +
Sbjct 1657 APTNLQFTEVTPESFRGTWDHGASDVSLYRITWAPVGNPDKMETILNGDENTLVFENLNP 1716
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNP-------PHNLSVINSEELS 237
+ EV + A + D + ++ P P NL V S
Sbjct 1717 N------TPYEVSITAIYPDESESEDLSGTERTLRLIPLTTQAPKSGPRNLQV--YNATS 1768
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ L + W S + KY I Y+ Q ++S +Q LKP T Y
Sbjct 1769 NSLTVKWDP---ASGRVQKYRITYQPSTGEGNEQTIT--VGGRQNSVLLQKLKPDTPYTI 1823
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
+ DG+G G T +P DPS + ++ + W
Sbjct 1824 TVYSQYPDGEGG----RMTGRGKT---KPLNTVRNLRVYDPSTS----SLSVRWD----- 1867
Query 358 EANGKILDYEVTLTRWKSHLQN---YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVL 414
A G Y++ + N + T+TV + + D
Sbjct 1868 HAEGNPRQYKLFYAPTSGGPEELVPIPGNTNYAILRNLQPDTPYTITVVPVYTEGDGGRT 1927
Query 415 TIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED 474
+ P N L V W V++Y + + ++ P +
Sbjct 1928 SDTGRTLVRGLARNIQVYNPTPNSLDVRWDPAPGPVQQYRIVYSPVAGTRPSES---IVV 1984
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE 534
RT L Y + + +Y+DG G+P + P S +R N
Sbjct 1985 PGNTRTVHLERLIPDTPYSVNIVALYSDGEGNPSPSQGRT--LPRSGPRNIRVFGETTNS 2042
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGN--ETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+ WD +G ++ Y I Y +G+ + V L L DT Y + +
Sbjct 2043 LSVAWDH-----ADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITV 2097
Query 593 AAYTDEGGKD 602
A ++G
Sbjct 2098 IAIYEDGDGG 2107
Score = 167 bits (422), Expect = 1e-40, Method: Composition-based stats.
Identities = 104/526 (20%), Positives = 172/526 (33%), Gaps = 54/526 (10%)
Query 98 NIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN 157
I ++EQ + I + +P PK+L + EW + +
Sbjct 607 RISFELTQSICLRIEQELAAIKKKAYVP---PKDLRFTQVTANSFKAEWSPPGDNVF--S 661
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPV 217
+ + + A + + TS ++ + V V AE G S I +
Sbjct 662 YHVTYKDANGDDEVTVVEPASSTSVVLN-NLRPETLYLVNVTAEYEDG--FSVPITGEET 718
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
P NL V + E + KLTW S +L+Y I+YR ++ T
Sbjct 719 TAEVKGVPRNLKVTD--ETTDSFKLTW---SQAPGRVLRYRIRYRPVSGGESKEV---ST 770
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
+ + T+++L P T+Y + G G +G + P D
Sbjct 771 PANQRRKTLENLTPDTKYEISVIAEYSSGPGS------PLTGNAATEEVRGNPRDLRVSD 824
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ-----NYTVNATKLTVNLT 392
+ + T++L W P GK+ Y VT T T L
Sbjct 825 ATTS----TLKLSWSRAP-----GKVKQYLVTYTPAAGGETQEVTVRGDTTTTMLRKLKE 875
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
+Y ++T G +A + + P + D + WT+ V+
Sbjct 876 GTQYDLSVTALYASGAGEALSGKGSTLE-ERGSPQNLVTKDITDTSIGAYWTSAPGMVRG 934
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
Y + W L D G T + NL Y I+V Y+ G G P + A
Sbjct 935 YRVSWKSLYDDIEA--GETTLPGDAIHTMI-ENLQPETKYKISVFATYSSGEGEPVTGDA 991
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVD 571
+ + SK +R + ++ + W P G + NY + YR G + V
Sbjct 992 TTELSQDSKI--LRVDEETEHTMRVTWKAAP-----GKVVNYRVVYRPQGGGRQMVAKVP 1044
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEG------GKDGPEFTFTTP 611
+ T L L T Y + + G G F +P
Sbjct 1045 PTVTSTVLKRLQPQTTYDITVLPMYKTGEGKLRQGSGTTASRFKSP 1090
Score = 161 bits (406), Expect = 1e-38, Method: Composition-based stats.
Identities = 84/496 (17%), Positives = 153/496 (31%), Gaps = 66/496 (13%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
E P NL + R W ++ + + KR +D
Sbjct 1386 EAPTNLVISERTHRSFRVSWTPPSDSV--------DRYKVEYYPVSGGKRQEFYVSRLDT 1437
Query 187 STVYF-----VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
STV + V V V D + K P +S+ + + +
Sbjct 1438 STVLKDLKPETDYVVNVY------SVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMH 1491
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+ W + Y + Y+ + ++ T + + L P TEY ++
Sbjct 1492 VQWQPVGGATG----YTVSYQPTRSPEGTKPKEMRVGPTVNDVQLTGLLPNTEYEVTVQA 1547
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ D SE A P P D +H+ T+ +VW+ + G
Sbjct 1548 VLYDLT------SEPAKAR-EVTLPLPRPQDVKLRDVTHS----TMNVVWEPV-----LG 1591
Query 362 KILDYEVTLTRWKSHLQNYTVNATKLTVNL----TNDRYLATLTVRNLVGKSDAAVLTIP 417
K+ Y V + V+ ++ + L + +Y +++ G S A
Sbjct 1592 KVRKYIVRYKTPDEEFKEVEVDRSRASTILKDLSSQTQYTVSVSAVYDEGTSPPATAYDT 1651
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
A + + P+ W V Y + W + + +
Sbjct 1652 TRRVPAPTNLQFTEVTPES--FRGTWDHGASDVSLYRITWAPVGNPD----KMETILNGD 1705
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY---------LKQAPPSKGPTVRTK 528
T + NL + Y +++T +Y D E + QAP S ++
Sbjct 1706 ENTLVFENLNPNTPYEVSITAIYPD-ESESEDLSGTERTLRLIPLTTQAPKSGPRNLQVY 1764
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT--IIGNETAVNVDSSHTEYTLSSLTSDT 586
N ++WD +G ++ Y I Y+ GNE + V L L DT
Sbjct 1765 NATSNSLTVKWDP-----ASGRVQKYRITYQPSTGEGNEQTITVGGRQNSVLLQKLKPDT 1819
Query 587 LYMVRMAAYTDEGGKD 602
Y + + + +G
Sbjct 1820 PYTITVYSQYPDGEGG 1835
Score = 155 bits (392), Expect = 4e-37, Method: Composition-based stats.
Identities = 98/573 (17%), Positives = 178/573 (31%), Gaps = 65/573 (11%)
Query 76 KEQYTIINRTASSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSC 134
K Q ++R +S D+ + + + + + + G +P +S
Sbjct 1426 KRQEFYVSRLDTSTVLKDLKPETDYVVNVYSVVEDEYSEPLKGTEKTLPVP-----VVSL 1480
Query 135 IVNE--GKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF 191
+ + M +W G T ++ K + + + +
Sbjct 1481 NIYDVGPTTMHVQWQPVGGATGYTVSYQPTRSPEGTKPK--EMRVGPTVNDVQLTGLLPN 1538
Query 192 VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS 251
EV V+A L +TS+ V P P V + S + + W
Sbjct 1539 TEYEVTVQAV--LYDLTSEPAKAREVTLPLPRP---QDVKLRDVTHSTMNVVWEP---VL 1590
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+ KY ++Y+T D + + +R+S ++DL T+Y + + ++G
Sbjct 1591 GKVRKYIVRYKTPD----EEFKEVEVDRSRASTILKDLSSQTQYTVSVSAVYDEGT---- 1642
Query 312 DWSEEASGI-TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S A+ T P+ + ++ P +G W + Y +T
Sbjct 1643 --SPPATAYDTTRRVPAPTNLQFTEVTPESFRG------TWD-----HGASDVSLYRITW 1689
Query 371 TRWK-----SHLQNYTVNATKLTVNLTNDRYLATLTV-RNLVGKSDA------AVLTIPA 418
+ N N N Y ++T +S+ + IP
Sbjct 1690 APVGNPDKMETILNGDENTLVFENLNPNTPYEVSITAIYPDESESEDLSGTERTLRLIPL 1749
Query 419 CDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
+L+ + N L V+W V+KY + + + + T G
Sbjct 1750 TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT---ITVGGR 1806
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVL 537
+ L L Y ITV Y DG G + + K + +R + +
Sbjct 1807 QNSVLLQKLKPDTPYTITVYSQYPDGEGGRMTGRGKTKPL--NTVRNLRVYDPSTSSLSV 1864
Query 538 EWDQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
WD G R Y +FY T G E V + + L +L DT Y + +
Sbjct 1865 RWDH-----AEGNPRQYKLFYAPTSGGPEELVPIPGNTNYAILRNLQPDTPYTITVVPVY 1919
Query 597 DEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAF 629
EG T T + P +
Sbjct 1920 TEGDGGRTSDTGRTLVRGLARNIQVYNPTPNSL 1952
Score = 155 bits (390), Expect = 7e-37, Method: Composition-based stats.
Identities = 88/546 (16%), Positives = 165/546 (30%), Gaps = 68/546 (12%)
Query 75 PKEQYTIINRTASSVTFTDIAS---LNIQLTCNILTFGQLEQNVYGITIISGLPP----- 126
P + TI+N +++ F ++ + +T I +++ G L P
Sbjct 1695 PDKMETILNGDENTLVFENLNPNTPYEVSITA-IYPDESESEDLSGTERTLRLIPLTTQA 1753
Query 127 --EKPKNLSCIVNEGKKMRCEWDG--GRETHLETNFTLKSEWATHKFADCKAKRDTPTSC 182
P+NL + +WD GR + + + +T + + +
Sbjct 1754 PKSGPRNLQVYNATSNSLTVKWDPASGRV----QKYRITYQPSTGEGNEQTITVGGRQNS 1809
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNP---PHNLSVINSEELSSI 239
+ + V ++ G+ + K P NL V + +S
Sbjct 1810 VLLQKLKPDTPYTITVYSQYPDGEGG------RMTGRGKTKPLNTVRNLRVYDP--STSS 1861
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
L + W + +Y + Y +P + +++L+P T Y +
Sbjct 1862 LSVRWDHAE---GNPRQYKLFYAPTSGGPEELVP---IPGNTNYAILRNLQPDTPYTITV 1915
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
+ +G G + T +P+ ++ + W P
Sbjct 1916 VPVYTEGDGG-------RTSDTGRTLVRGLARNIQVYNPT----PNSLDVRWDPAP---- 1960
Query 360 NGKILDYEVTLTRWKSH--LQNYTVNATKLTVNLTN----DRYLATLTVRNLVGKSDAAV 413
G + Y + + ++ V TV+L Y + G+ + +
Sbjct 1961 -GPVQQYRIVYSPVAGTRPSESIVVPGNTRTVHLERLIPDTPYSVNIVALYSDGEGNPSP 2019
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQE 473
+ P N L V W V++Y + + I ++
Sbjct 2020 SQ--GRTLPRSGPRNIRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD--PIDEYTTV 2075
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN 533
G + L+ L Y ITV +Y DG G + P +
Sbjct 2076 PGRRNNVILQ-PLQPDTPYKITVIAIYEDGDGGHLTGNGRTVGLLP--PQNIHIFDEWYT 2132
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
+ WD P + Y I Y+ + NE T YTL +L T Y V +
Sbjct 2133 RFRVSWDPSP-----SPVLGYKIVYKPVGSNEPMEAFVGEVTSYTLHNLNPSTTYDVSVY 2187
Query 594 AYTDEG 599
A D G
Sbjct 2188 AQYDSG 2193
Score = 147 bits (370), Expect = 2e-34, Method: Composition-based stats.
Identities = 78/482 (16%), Positives = 149/482 (31%), Gaps = 54/482 (11%)
Query 129 PKNLSCIVNEGKKMRCEWD--GGRETHLETNFT-LKSEWATHKFADCKAKRDTPTSCTVD 185
P+NL + W GR + + + +R T + T D
Sbjct 726 PRNLKVTDETTDSFKLTWSQAPGRVLRYRIRYRPVSGGESKEVSTPANQRRKTLENLTPD 785
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
E+ V AE + G + + + P +L V S+ +S LKL+W
Sbjct 786 ------TKYEISVIAEYSSG--PGSPLTGNAATEEVRGNPRDLRV--SDATTSTLKLSW- 834
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
S + +Y + Y ++ ++ ++ LK T+Y + +
Sbjct 835 --SRAPGKVKQYLVTYTPAAGGETQEVTVR---GDTTTTMLRKLKEGTQYDLSVTALYAS 889
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G G + G T E+R +P D + T ++ W + P G +
Sbjct 890 GAGE----ALSGKGSTLEER--GSPQNLVTKDITDT----SIGAYWTSAP-----GMVRG 934
Query 366 YEVTLT------RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
Y V+ T + +Y ++ G+ + V
Sbjct 935 YRVSWKSLYDDIEAGETTLPGDAIHTMIENLQPETKYKISVFATYSSGEGEP-VTGDATT 993
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ ++ + ++ + V W V Y + + + + TV
Sbjct 994 ELSQDSKILRV-DEETEHTMRVTWKAAPGKVVNYRVVYRPQGGGRQMVA---KVPPTVTS 1049
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
T L+ L Y ITV P+Y G G + ++T + + W
Sbjct 1050 TVLK-RLQPQTTYDITVLPMYKTGEGKLRQGSGTTA-SRFKSPRNLKTSDPTMSSFRVTW 1107
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNET--AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
+ P G ++ Y + + + + + L L + T Y V + D
Sbjct 1108 EPAP-----GEVKGYKVTFHPTGDDRRLGELVLGPYDNTVVLEELRAGTTYRVNVFGMFD 1162
Query 598 EG 599
G
Sbjct 1163 GG 1164
Score = 117 bits (292), Expect = 3e-25, Method: Composition-based stats.
Identities = 81/543 (15%), Positives = 146/543 (27%), Gaps = 50/543 (9%)
Query 76 KEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCI 135
EQ + +SV + + T + + + P +NL
Sbjct 1797 NEQTITVGGRQNSVLLQKLK-PDTPYTITVYSQYPDGEGGRMTGRGKTKPLNTVRNLRVY 1855
Query 136 VNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIE 195
+ WD + L T + T+ + +
Sbjct 1856 DPSTSSLSVRWD--HAEGNPRQYKLFYA-PTSGGPEELVPIPGNTNYAILRNLQPDTPYT 1912
Query 196 VWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
+ V G + + N+ V N + L + W +
Sbjct 1913 ITVVPVYTEGDGGRTSDTGRTLVRGLA---RNIQVYNP--TPNSLDVRWDP---APGPVQ 1964
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+Y I Y + S+ + ++ L P T Y I + DG+G S
Sbjct 1965 QYRIVYSPVAGTRPSESIV--VPGNTRTVHLERLIPDTPYSVNIVALYSDGEGNPS---- 2018
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
+ G T P P + ++ + W A+G + Y + +
Sbjct 2019 PSQGRTL---PRSGPRNIRVFGETTN----SLSVAWD-----HADGPVQQYRIIYSPTVG 2066
Query 376 ----HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
+ + +TV + D LT P
Sbjct 2067 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAIYEDGDGGHLTGNGRTVGLLPPQNIHI 2126
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
V W V Y + + + P + G V L NL S
Sbjct 2127 FDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEP----MEAFVGEVTSYTLH-NLNPSTT 2181
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
Y ++V Y G P + + + ++T +VG + ++W
Sbjct 2182 YDVSVYAQYDSGLSVPLTDQGTTLYLNVT---DLKTYQVGWDTFCVKWSPHRA------A 2232
Query 552 RNYTIFYRTIIG-NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG-PEFTFT 609
+Y + G + V S T + + L+ + Y V + T G P T
Sbjct 2233 TSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPEAEYGVTVFVQTPNLEGPGVPIKEQT 2292
Query 610 TPK 612
T K
Sbjct 2293 TVK 2295
Score = 113 bits (281), Expect = 7e-24, Method: Composition-based stats.
Identities = 53/314 (17%), Positives = 99/314 (32%), Gaps = 28/314 (9%)
Query 351 WKTLPPFEANGKILDYEVTLTRWKSHLQNYTV---NATKLTVN--LTNDRYLATLTVRNL 405
W + Y VT + V ++T + +N YL +T
Sbjct 652 WSPPGDN-----VFSYHVTYKDANGDDEVTVVEPASSTSVVLNNLRPETLYLVNVTAEYE 706
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAP 465
G S + + + + D+ + W+ V +Y + + +S
Sbjct 707 DGFSVPITGEETTAEVKGVPRNLKVTDETTDS-FKLTWSQAPGRVLRYRIRYRPVSGGES 765
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
+ R NL Y I+V Y+ GPGSP + A ++ +
Sbjct 766 K----EVSTPANQRRKTLENLTPDTKYEISVIAEYSSGPGSPLTGNAATEEVR-GNPRDL 820
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET-AVNVDSSHTEYTLSSLTS 584
R + L W + P G ++ Y + Y G ET V V T L L
Sbjct 821 RVSDATTSTLKLSWSRAP-----GKVKQYLVTYTPAAGGETQEVTVRGDTTTTMLRKLKE 875
Query 585 DTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAI---VVPVCLAFLLTTLLGVLFCF 641
T Y + + A G + +T + + + + T+ G++ +
Sbjct 876 GTQYDLSVTALYASGAGEALSGKGSTLEERGSPQNLVTKDITDTSIGAYWTSAPGMVRGY 935
Query 642 NKRDLIKKHIWPNV 655
K ++ ++
Sbjct 936 RVS---WKSLYDDI 946
Score = 66.8 bits (161), Expect = 9e-10, Method: Composition-based stats.
Identities = 87/564 (15%), Positives = 171/564 (30%), Gaps = 56/564 (10%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
PP NL V +E S ++L+W + Y I A + +
Sbjct 335 EPPSNLVV--TELSSKYIRLSWDP---SPSAVTGYKILLTPMAAGSRHH--ALSVGPQTT 387
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
+ V+DL TEY + MK + E+ + + S+ I
Sbjct 388 TLNVRDLTADTEYQISVFAMKGLTSSEPTSVMEKTQPMKVQVECSRGVDIKADI-VFLVD 446
Query 343 GYRTVQLVWKTLPPFEANGKIL--DYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL 400
G ++ + A ++L +E++ R + L Y+ + +R +
Sbjct 447 GSYSIGIA--NFVKVRAFLEVLAKSFEISPNRVQISLVQYSRDPHTEFTLKEFNRVEDII 504
Query 401 TVRNLV---GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE-------WTTPRESV 450
N G S + + P ++ M+ + + P +
Sbjct 505 KAINTFPYRGGSTNTGKAMTYVREKIFVPNKGSRSNVPKVMILITDGKSSDAFRDPAIKL 564
Query 451 KKYILEWCVLSDKAPCITDWQQE--DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE 508
+ +E + K ++ + + + + + E
Sbjct 565 RNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFEL---TQSICLRIE 621
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV 568
A +K+ +R +V N EW + +Y + Y+ G++
Sbjct 622 QELAAIKKKAYVPPKDLRFTQVTANSFKAEWSPP-----GDNVFSYHVTYKDANGDDEVT 676
Query 569 NV-DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFA-QGEIEAIVVPVC 626
V +S T L++L +TLY+V + A ++G F+ P + E VP
Sbjct 677 VVEPASSTSVVLNNLRPETLYLVNVTAEYEDG--------FSVPITGEETTAEVKGVPRN 728
Query 627 LAFLLTTLLGVLFCFNK---RDLIKKHIW--------PNVPDPSKSHIAQWSPHTPPRHN 675
L T +++ R L + + V P+ TP
Sbjct 729 LKVTDETTDSFKLTWSQAPGRVLRYRIRYRPVSGGESKEVSTPANQRRKTLENLTPDTKY 788
Query 676 FNSKDQMYSDGN-FTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCM 734
S YS G E P DL+ D + + G +
Sbjct 789 EISVIAEYSSGPGSPLTGNAATEEVRGNP--RDLRVSDATTSTLKLSWSRAPGKVKQYLV 846
Query 735 SSSRPSISSSDENESSQNTSSTVQ 758
+ + + + E +T++T+
Sbjct 847 TYTPAAGGETQEVTVRGDTTTTML 870
Score = 46.8 bits (109), Expect = 0.001, Method: Composition-based stats.
Identities = 21/82 (26%), Positives = 35/82 (43%), Gaps = 8/82 (10%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
+PP +L+ +E + ++W P I+ Y I T D +T A++ +
Sbjct 26 DPPSDLNFKIIDEN--TVHMSWERPVDP---IVGYRI---TVDPTTDGPTKEFTLAASTT 77
Query 283 SFTVQDLKPFTEYVFRIRCMKE 304
+ DL P T+YV I E
Sbjct 78 ETLLSDLIPETQYVVTITSYNE 99
Score = 44.5 bits (103), Expect = 0.005, Method: Composition-based stats.
Identities = 36/254 (14%), Positives = 79/254 (31%), Gaps = 26/254 (10%)
Query 75 PKEQYTIINRTASSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLS 133
P ++YT + ++V + ++T + ++ G GL P P+N+
Sbjct 2068 PIDEYTTVPGRRNNVILQPLQPDTPYKITVIAIYEDGDGGHLTGNGRTVGLLP--PQNIH 2125
Query 134 CIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN 193
+ R WD L K + + + T ++ ST Y V+
Sbjct 2126 IFDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEVTSYTLHNLNPSTTYDVS 2185
Query 194 IEVWVEAENALGKVTSDH---INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
V+ + ++ L +D + + + + + W+
Sbjct 2186 --VYAQYDSGLSVPLTDQGTTLYLNVTD-----------LKTYQVGWDTFCVKWSPHRAA 2232
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
+ Y ++ D + +I + +S L P EY + + +G
Sbjct 2233 TS----YRLKLSPADGTRGQEITVR---GSETSHCFTGLSPEAEYGVTVFVQTPNLEGPG 2285
Query 311 SDWSEEASGITYED 324
E+ + E
Sbjct 2286 VPIKEQTTVKPTEA 2299
Score = 40.2 bits (92), Expect = 0.11, Method: Composition-based stats.
Identities = 15/100 (15%), Positives = 29/100 (29%), Gaps = 4/100 (4%)
Query 418 ACDFQATHPVMDLKAFPKDNM-LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
+ P +L + + + W +V Y + +L+ A G
Sbjct 328 VSGEEVIEPPSNLVVTELSSKYIRLSWDPSPSAVTGYKI---LLTPMAAGSRHHALSVGP 384
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
T +L Y I+V + P S+ +
Sbjct 385 QTTTLNVRDLTADTEYQISVFAMKGLTSSEPTSVMEKTQP 424
>sp|P51641|CNTFR_CHICK Ciliary neurotrophic factor receptor subunit
alpha OS=Gallus gallus OX=9031 GN=CNTFR PE=2 SV=1
Length=362
Score = 164 bits (415), Expect = 3e-43, Method: Composition-based stats.
Identities = 59/294 (20%), Positives = 110/294 (37%), Gaps = 31/294 (11%)
Query 82 INRTASSVTFTDIASLNIQLTCNILTFGQLEQNV-YGITIISGLPPEKPKNLSCIVNEGK 140
I+ + + ++ + ++++ + + ++ Y + G+PP++P + N K
Sbjct 62 IDDSHLNGSYLILKNVDLTQSGQYSCYEGSSWHLKYQTYLRVGVPPKEPVLMCRSNNYPK 121
Query 141 KMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY-FVNIEVWVE 199
C W T++ +F + T + C+ C + Y ++ V +V +
Sbjct 122 GFYCSWHLPSPTYIPNSFNISVIHGTREMV-CEKDIFPKNRCHIRYLQLFSTVKYKVTLT 180
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS---IKSVIILK 256
NALGK S + FD VKP+PP ++ L+++W NPS LK
Sbjct 181 VTNALGK-NSTTLTFDEFAIVKPDPPESVVAKPVPNNPRRLEVSWQNPSSWPDPESFPLK 239
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
+ ++YR W + D +S T+ D EY+ ++ ++ G WSDWS
Sbjct 240 FFLRYRPLILDQWQHVELSD----GTSHTITDAYAGKEYIIQVAAK-DNDIGTWSDWSVA 294
Query 317 ASGITYEDRPSK-------------------APSFWYKIDPSHTQGYRTVQLVW 351
+ + P P D G V + W
Sbjct 295 VHATPWTEEPKHLTTEVQITETTSTSTSSFMPPPTTKICDKGAGVGSGAVAVCW 348
Score = 42.2 bits (97), Expect = 0.017, Method: Composition-based stats.
Identities = 25/109 (23%), Positives = 42/109 (39%), Gaps = 7/109 (6%)
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN---MLWVEWTTPR--ES 449
+Y TLTV N +GK ++ LT P + A P N L V W P
Sbjct 174 KYKVTLTVTNALGK-NSTTLTFDEFAIVKPDPPESVVAKPVPNNPRRLEVSWQNPSSWPD 232
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
+ + L++ + + WQ + + ++ + K Y+I V
Sbjct 233 PESFPLKFFLRYRPL-ILDQWQHVELSDGTSHTITDAYAGKEYIIQVAA 280
>sp|Q2EY14|PRTGA_DANRE Protogenin A OS=Danio rerio OX=7955 GN=prtga
PE=2 SV=1
Length=1149
Score = 173 bits (439), Expect = 5e-43, Method: Composition-based stats.
Identities = 102/622 (16%), Positives = 193/622 (31%), Gaps = 54/622 (9%)
Query 20 STGELLDPCGYIS-PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQ 78
+ +L P + PES VC I W N +
Sbjct 306 ANITVLAPPSLVEWPESVTRPRAGTARFVCT-------AEGFPTPQITWLKNGEPVRSNG 358
Query 79 YTIINRTASSVTFTDIASLNIQLTCNILTF-GQLEQNVYGITIISGLPPEKPKNLSCIVN 137
+ + + I + C G + I ++S P P+N+
Sbjct 359 RIKMYNSKLVIN-QIIPEDDGIYQCEAENIQGSVLAMARLIVVMSDNRPSAPRNIRADTV 417
Query 138 EGKKMRCEWD-GGRETHLETNFTLKSEWATH-KFADCKAKRDTPTSCTVDYSTVYFVNIE 195
+ WD + +++ A + + T+ + N
Sbjct 418 SSSAIVLAWDRPAYNSEKVIAYSVHYMKAEGLNNEEYQIVIGNDTTRYIIDDLEAGRNYT 477
Query 196 VWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN--PSIKSV 252
++ A +G SDH+ + V P + + S ++++W +
Sbjct 478 FYIVAYMPMGASRMSDHVIQHTLEDVPLRAPE---LSLTSRSPSDIQVSWQPLSHKLSRG 534
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ Y + YRT T +Q+ ++ ++ ++ L+P T Y+ RI G G S
Sbjct 535 RVSAYRLSYRTSSDGTLTQLE---LSAHKTHQLLEGLQPDTTYLLRIAAATAVGWGEPSA 591
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA--NGKILDYEVTL 370
WS + + AP + TV L W + G L Y
Sbjct 592 WSSHRTPKASSTKVPLAPEL-----QLESLNCTTVTLRWHLPAGSSSGLQGFKLSYHEEG 646
Query 371 TRWKSHLQNYTVNATKLTVNL-TNDRYLATLTVRNLVGK--------SDAAVLTIPACDF 421
+ Q + L +Y L + +G S +++
Sbjct 647 QSEAAQAQIPPHHRQHTIGGLDPRKKYHIKLLAFSFMGDGYQADQTISTPGCVSVRDRLV 706
Query 422 QATHPVMDLKAFP-KDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
P + A + +++ W P Y + + + + + Q T
Sbjct 707 PPPPPPHHVYAHSNSSSSVFLHWARPAFTSAQTLNYTVRCNPVGLQNASLVLYLQ---TA 763
Query 478 HRTYLRGNLAESKCYLITVT--PVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
++ L +L + Y V P SP + L +AP V+ + + A
Sbjct 764 AQSLLVTDLEPNTNYEFAVRLHVDLLSSPWSPVVYQTTLPEAPSRAPVGVKVTLIEGDSA 823
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTII----GNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
++ W P D + +YT+ Y T G+ + + S T L +L +Y+V+
Sbjct 824 LVSWKA-PDDRSAAAVTHYTVLYATRRAWAAGDWQMLQREGSITMALLENLQPGQVYLVQ 882
Query 592 MAAYTDEGGKDGP---EFTFTT 610
++A G E T T
Sbjct 883 VSASNQMGDGPFSAAVELTIHT 904
Score = 134 bits (338), Expect = 7e-31, Method: Composition-based stats.
Identities = 105/661 (16%), Positives = 201/661 (30%), Gaps = 95/661 (14%)
Query 1 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV 60
M + + L L +FL+ + P C +
Sbjct 1 MASFKRDLYLFLAVFLSISGVWSFSELFFIKEPHDVTAMRRDAVVLDCQAHGEA------ 54
Query 61 NANYIVWKTNHFTIPKEQ--YTIINRT--ASSVTFTDIASLNIQLTCNILT--FGQLEQN 114
I W N TI + + Y++ N + S V S C L Q
Sbjct 55 -PIGIRWLKNGVTITESERVYSLSNGSLLISEVESRKDKSDEGFYQCLAQNKYGSILSQR 113
Query 115 VYGITIISGLPPEKPKNLSCIVNEGKKMRC----------EWDGGRETH-LETNFTLKSE 163
++P ++ + + C W+ R T L T
Sbjct 114 ARLTIASLSTFTQQPASIIVMEGSVARFTCKITATPPPIITWEFNRVTLPLATERITVLP 173
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN 223
+ + + C A N + + S + P
Sbjct 174 SGVLQIQGVEQRDAGSYRCV----------------AANIVSRRRSTEATLTVTPAMSPR 217
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P +I + ++ P+ + +L+ + +WS+ + ++
Sbjct 218 APQRPRIIAGPQNLTV-------PAHST-ALLECMASGNPRPLISWSRADHKSIDVHKTK 269
Query 284 FT------VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS--------KA 329
+ D+ P ++ R + +++ A+ IT PS
Sbjct 270 VLGNGNLIISDVNPQHAGIYFCRATTPGTR----NYTIAAANITVLAPPSLVEWPESVTR 325
Query 330 PSFWYKIDPSHTQGYRTVQLVW-KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLT 388
P +G+ T Q+ W K P +NG+I Y +KL
Sbjct 326 PRAGTARFVCTAEGFPTPQITWLKNGEPVRSNGRIKMYN-----------------SKLV 368
Query 389 VN--LTNDRYLATLTVRNLVGKSDA-AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT 445
+N + D + N+ G A A L + D + + P + + + W
Sbjct 369 INQIIPEDDGIYQCEAENIQGSVLAMARLIVVMSDNRPSAPRNIRADTVSSSAIVLAWDR 428
Query 446 P---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD 502
P E V Y + + + + ++Q G Y+ +L + Y +
Sbjct 429 PAYNSEKVIAYSVHY--MKAEGLNNEEYQIVIGNDTTRYIIDDLEAGRNYTFYIVAYMPM 486
Query 503 G-PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT- 560
G + + + + P + P + ++ + W L + G + Y + YRT
Sbjct 487 GASRMSDHVIQHTLEDVPLRAPELSLTSRSPSDIQVSWQPLSHKLSRGRVSAYRLSYRTS 546
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIE 619
G T + + + T L L DT Y++R+AA T G G+ + TPK + ++
Sbjct 547 SDGTLTQLELSAHKTHQLLEGLQPDTTYLLRIAAATAVGWGEPSAWSSHRTPKASSTKVP 606
Query 620 A 620
Sbjct 607 L 607
Score = 109 bits (273), Expect = 4e-23, Method: Composition-based stats.
Identities = 93/619 (15%), Positives = 184/619 (30%), Gaps = 90/619 (15%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIP--KEQYTIINRTASSVT 90
P S +V S C I W+ N T+P E+ T++ +
Sbjct 128 PASIIVMEGSVARFTC-------KITATPPPIITWEFNRVTLPLATERITVLPSGVLQIQ 180
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPK---------NLSCIVNEGKK 141
+ + +T+ + P P+ NL+ +
Sbjct 181 GVEQRDAGSYRCVAANIVSRRRSTEATLTVTPAMSPRAPQRPRIIAGPQNLTVPAHSTAL 240
Query 142 MRC----------EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF 191
+ C W ++ + T +D + C +T
Sbjct 241 LECMASGNPRPLISWSRADHKSIDVHKTKVLGNGNLIISDVNPQHAGIYFC--RATTPGT 298
Query 192 VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN---PS 248
N + A + + + P +P V +E + ++TW P
Sbjct 299 RNYTI---AAANITVLAPPSLVEWPESVTRPRAGTARFVCTAEGFPT-PQITWLKNGEPV 354
Query 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
+ I YN + +QI PED +++ G
Sbjct 355 RSNGRIKMYNSKLVI------NQIIPEDDG-----------------IYQCEAENIQGSV 391
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
+ ++RPS AP + T + L W P + K++ Y V
Sbjct 392 L---AMARLIVVMSDNRPS-APRNIR----ADTVSSSAIVLAWD--RPAYNSEKVIAYSV 441
Query 369 TLTRWKSHLQN-----YTVNATKLTVNLT--NDRYLATLTVRNLVGKSDAA--VLTIPAC 419
+ + + T+ ++ Y + +G S + V+
Sbjct 442 HYMKAEGLNNEEYQIVIGNDTTRYIIDDLEAGRNYTFYIVAYMPMGASRMSDHVIQHTLE 501
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
D P + L + + + V W + + + + + + T Q E
Sbjct 502 DVPLRAPELSLTSRSPSD-IQVSWQPLSHKLSRGRVSAYRLSYRTSSDGTLTQLELSAHK 560
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKA-YLKQA----PPSKGPTVRTKKVGKN 533
L L YL+ + A G G P + + +A P P ++ + +
Sbjct 561 THQLLEGLQPDTTYLLRIAAATAVGWGEPSAWSSHRTPKASSTKVPLA-PELQLESLNCT 619
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRM 592
L W LP +G ++ + + Y +E + H ++T+ L Y +++
Sbjct 620 TVTLRW-HLPAGSSSG-LQGFKLSYHEEGQSEAAQAQIPPHHRQHTIGGLDPRKKYHIKL 677
Query 593 AAYTDEGGKDGPEFTFTTP 611
A++ G + T +TP
Sbjct 678 LAFSFMGDGYQADQTISTP 696
>sp|Q23551|UNC22_CAEEL Twitchin OS=Caenorhabditis elegans OX=6239
GN=unc-22 PE=1 SV=3
Length=7158
Score = 173 bits (439), Expect = 1e-42, Method: Composition-based stats.
Identities = 95/499 (19%), Positives = 160/499 (32%), Gaps = 37/499 (7%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH----LETNFTLKSEWATHKFADCKAKRDTPT 180
PP P + ++ W+ R+ L + +A K T
Sbjct 4634 PPGAPSTPEITGYDTNQVSLAWNPPRDDGGSPILGYVVERFEKRGGGDWAPVKMPMVKGT 4693
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVT----SDHINFDPVYKVKPNPPHNLSVINSEEL 236
C V + V A NA G S+ + P Y KP P V +
Sbjct 4694 ECIVPGLHE-NETYQFRVRAVNAAGHGEPSNGSEPVTCRP-YVEKPGAPDAPRVGKITKN 4751
Query 237 SSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
S+ +LTW P I Y ++ + + W++ + T F V++L EY
Sbjct 4752 SA--ELTWNRPLRDGGAPIDGYIVEKKKLGDNDWTRCNDKPVRDTA--FEVKNLGEKEEY 4807
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
FR+ + G+G S S+ RP + I + + +++ +
Sbjct 4808 EFRVIAVNSAGEGEPSKPSDLVLIEEQPGRPIFDINNLKDITVRAGETIQ-IRIPYAGGN 4866
Query 356 PFE------ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
P N I + E T+ T +K +D ++ N GK
Sbjct 4867 PKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSK-----RSDAGPYKISATNKYGKD 4921
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITD 469
+ + D + + W P+++ I + V +K D
Sbjct 4922 TCKLNVFVLDAPGKPTGPIRATDIQAD-AMTLSWRPPKDNGGDAITNYVV--EKRTPGGD 4978
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-ESIKAYLKQAP---PSKGPTV 525
W V T NL + Y V G G P E+ A + + P P
Sbjct 4979 WVTVGHPVGTTLRVRNLDANTPYEFRVRAENQYGVGEPLETDDAIVAKNPFDTPGAPGQP 5038
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSS--HTEYTLSSLT 583
+ + L+W + P I+ Y I R + E + T++ ++ LT
Sbjct 5039 EAVETSEEAITLQWTR-PTSDGGAPIQGYVIEKREVGSTEWTKAAFGNILDTKHRVTGLT 5097
Query 584 SDTLYMVRMAAYTDEGGKD 602
Y R+AAY G +
Sbjct 5098 PKKTYEFRVAAYNAAGQGE 5116
Score = 172 bits (435), Expect = 3e-42, Method: Composition-based stats.
Identities = 84/509 (17%), Positives = 167/509 (33%), Gaps = 56/509 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHKFADCKAKRDTPTSC 182
PP+ P +++ + +G + W+ + T + ++++ +K + + P +
Sbjct 1891 PPKGPLDIADVCADGATL--SWNPPDDDGGDPLTGYIVEAQDMDNKGKYIEVGKVDPNTT 1948
Query 183 TVDYSTVYFV-NIEVWVEAENALGKVTSDHINFDPVYKVK-----PNPPHNLSVINSEEL 236
T+ + + N + V+A N G S+ ++ D ++K P P + + +
Sbjct 1949 TLKVNGLRNKGNYKFRVKAVNNEG--ESEPLSADQYTQIKDPWDEPGKPGRPEITDFD-- 2004
Query 237 SSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+ + + W P I +Y ++ R D W ++ ++ ++ LK EY
Sbjct 2005 ADRIDIAWEPPHKDGGAPIEEYIVEVRDPDTKEWKEVKRV----PDTNASISGLKEGKEY 2060
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
FR+R + + G G S+ SE+ +P P++ + + W+
Sbjct 2061 QFRVRAVNKAGPGQPSEPSEKQL-----AKPKFIPAWLKHDNLKSITVKAGATVRWEVKI 2115
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL--------------ATLT 401
E + +W Q N +LT++ + + LT
Sbjct 2116 GGEP--------IPEVKWFKGNQQ-LENGIQLTIDTRKNEHTILCIPSAMRSDVGEYRLT 2166
Query 402 VRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
V+N G + + +++ +DN L + W P + +E+ +
Sbjct 2167 VKNSHGADEEKANLTVLDRPSKPNGPLEVSDVFEDN-LNLSWKPPDDD-GGEPIEYYEVE 2224
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
W L + + Y V V +G S K P
Sbjct 2225 KLDTATGRWVPCAKVKDTKAHIDGLKKGQTYQFRVKAVNKEGASDALSTDKDTKAKNPYD 2284
Query 522 GP----TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHT 575
P T + LEW+ P I Y I + G + V T
Sbjct 2285 EPGKTGTPDVVDWDADRVSLEWEP-PKSDGGAPITQYVIEKKGKHGRDWQECGKVSGDQT 2343
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
+ L Y R+ A G +
Sbjct 2344 NAEILGLKEGEEYQFRVKAVNKAGPGEAS 2372
Score = 168 bits (425), Expect = 5e-41, Method: Composition-based stats.
Identities = 91/554 (16%), Positives = 171/554 (31%), Gaps = 25/554 (5%)
Query 62 ANYIVWKTNHFTIPKE-QYTIINRTASSVTFTDIASLNIQLTC-NILTFGQLEQNVYGIT 119
A I W N + I N T ++ T ++ I+ + ++ + +
Sbjct 3592 APKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNESGKDEHEVD 3651
Query 120 IISGLPPEKPKN-LSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHKFADCKAKR 176
+ P P+ L + + +WD + TN+ ++ + ++ C
Sbjct 3652 VNILDIPGAPEGPLRHKDITKESVVLKWDEPLDDGGSPITNYVVEKQEDGGRWVPCGETS 3711
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKV---TSDHINFDPVYKVKPNPPHNLSVINS 233
D TS V+ + + V+A N G TSDH +P+ P + V
Sbjct 3712 D--TSLKVNKLSEGH-EYKFRVKAVNRQGTSAPLTSDHAIVAKNPFDEPDAPTD--VTPV 3766
Query 234 EELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
+ + L W P+ I Y ++ + K + + T +L P
Sbjct 3767 DWDKDHVDLEWKPPANDGGAPIDAYIVEKKDKFGDW---VECARVDGKTTKATADNLTPG 3823
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
Y FR++ + + G G SD + P + + + + + ++
Sbjct 3824 ETYQFRVKAVNKAGPGKPSDPTGNVVAKPRRMAPKLNLAGLLDLRIKAGTPIK-LDIAFE 3882
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
P A K D + T +A + + D + + V N GK A
Sbjct 3883 GEPAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYKIIVENEHGKDTAQ 3942
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQ 472
+ + K+ + W P ++ +L + V T WQ+
Sbjct 3943 CNVTVLDVPGTPEGPLKIDEIHKEGCT-LNWKPPTDNGGTDVLHYIVEKMDTSRGT-WQE 4000
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP----ESIKAYLKQAPPSKGPTVRTK 528
T L K Y V V G P E I A + P
Sbjct 4001 VGTFPDCTAKVNKLVPGKEYAFRVKAVNLQGESKPLEAEEPIIAKNQFDVPDPVDKPEVT 4060
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLY 588
K+ ++W+ + + Y + + + T ++ +L Y
Sbjct 4061 DWDKDRIDIKWNPT-ANNGGAPVTGYIVEKKEKGSAIWTEAGKTPGTTFSADNLKPGVEY 4119
Query 589 MVRMAAYTDEGGKD 602
R+ A G D
Sbjct 4120 EFRVIAVNAAGPSD 4133
Score = 167 bits (423), Expect = 8e-41, Method: Composition-based stats.
Identities = 105/602 (17%), Positives = 181/602 (30%), Gaps = 57/602 (9%)
Query 35 SPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDI 94
V+ I + I + + T+++ + T
Sbjct 4847 DITVRAGETIQIRIPYAGGN------PKPIIDLFNGNSPIFENERTVVDVNPGEIVITTT 4900
Query 95 ASLNIQLTC-NILTFGQLEQNVYGITIISGLPPEKPKN-LSCIVNEGKKMRCEWDGGRET 152
S I + ++ + + P KP + + M W ++
Sbjct 4901 GSKRSDAGPYKISATNKYGKDTCKLNVFVLDAPGKPTGPIRATDIQADAMTLSWRPPKDN 4960
Query 153 HLE--TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD 210
+ TN+ ++ + T + E V AEN G
Sbjct 4961 GGDAITNYVVEKRTPGGDWVTVGHPVGTTLRVR---NLDANTPYEFRVRAENQYGVGEPL 5017
Query 211 HINFDPVYKVK---PNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDA 266
+ V K P P E + L WT P+ I Y I+ R +
Sbjct 5018 ETDDAIVAKNPFDTPGAPGQPEA--VETSEEAITLQWTRPTSDGGAPIQGYVIEKREVGS 5075
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
+ W++ + T+ V L P Y FR+ G+G +S S IT ++ P
Sbjct 5076 TEWTKAAFGNILDTKHR--VTGLTPKKTYEFRVAAYNAAGQGEYSVNSVP---ITADNAP 5130
Query 327 SKAPSFWYKI--DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ------ 378
++ + D G R LV P +VT ++ ++ +
Sbjct 5131 TRPKINMGMLTRDILAYAGERAKILVPFAASPAP--------KVTFSKGENKISPTDPRV 5182
Query 379 --NYTVNATKLTVNL--TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP 434
Y+ LT+ D L + + N G SD+A + + D A+ + ++
Sbjct 5183 KVEYSDFLATLTIEKSELTDGGLYFVELENSQG-SDSASIRLKVVDKPASPQHIRVEDIA 5241
Query 435 KDNMLWVEWTTPRESVKKYILEWCVLSDKAP-CITDWQQEDGTVHRT-YLRGNLAESKCY 492
D + W P I + V W++ V Y G L + Y
Sbjct 5242 PD-CCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKVSSFVRNLNYTVGGLIKDNRY 5300
Query 493 LITVTPVYADGPGSP----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
V G P + + A + P++ + A LEWD P
Sbjct 5301 RFRVRAETQYGVSEPCELADVVVAKYQFEVPNQPEAPTVRDKDSTWAELEWD--PPRDGG 5358
Query 549 GFIRNYTIFYR-TIIGNETAVNVDSSHT-EYTLSSLTSDTLYMVRMAAYTDEG-GKDGPE 605
I Y + YR T G +D S ++ L + + R+ A G K P
Sbjct 5359 SKIIGYQVQYRDTSSGRWINAKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPP 5418
Query 606 FT 607
Sbjct 5419 SE 5420
Score = 167 bits (423), Expect = 1e-40, Method: Composition-based stats.
Identities = 92/520 (18%), Positives = 164/520 (32%), Gaps = 46/520 (9%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETH---LETNFTLKSEWATHKFADCKAKRDTPTSC 182
PE P +S + + W ++ + K + T+ + A T TS
Sbjct 4246 PEGPLEVSDVTKD--SCVLNWKPPKDDGGAEISNYVVEKRDTKTNTWVPVSA-FVTGTSI 4302
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK---PNPPHNLSVINSEELSSI 239
TV T E V AEN G+ S + + + K P P +++++ +
Sbjct 4303 TVPKLTEGH-EYEFRVMAENTFGRSDSLNTDEPVLAKDPFGTPGKPGRPEIVDTD--NDH 4359
Query 240 LKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ + W P + Y+I+ + W ++ T F+ ++ Y +R
Sbjct 4360 IDIKWDPPRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQGTA--FSDTRVQKGHTYEYR 4417
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+ + + G G SD S A+ + P K + + + P +
Sbjct 4418 VVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRVKAGEPLVITIPFTASPQPD 4477
Query 359 ANGKILDYEVTLTRWKSH---LQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAV 413
++ T+ T + TKL + T D + N G+++A +
Sbjct 4478 ---------ISWTKEGGKPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANI 4528
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQE 473
I D + A + + W P++ I + + + W +
Sbjct 4529 -KITVIDKPGAPENITYPAVSRHTCT-LNWDAPKDDGGAEIAGYKIEYQEVGSQI-WDKV 4585
Query 474 DGTVHRT-YLRGNLAESKCYLITVTPVYADG-----PGSPESIKAYLKQAPPSKGPTVRT 527
G + T Y L + Y + A G G P IK PP T
Sbjct 4586 PGLISGTAYTVRGLEHGQQYRFRIRAENAVGLSDYCQGVPVVIKD--PFDPPGAPSTPEI 4643
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD---SSHTEYTLSSLTS 584
N+ L W+ P D I Y + G V TE + L
Sbjct 4644 TGYDTNQVSLAWNP-PRDDGGSPILGYVVERFEKRGGGDWAPVKMPMVKGTECIVPGLHE 4702
Query 585 DTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVP 624
+ Y R+ A G + + P + +E P
Sbjct 4703 NETYQFRVRAVNAAGHGEPSNG--SEPVTCRPYVEKPGAP 4740
Score = 164 bits (415), Expect = 7e-40, Method: Composition-based stats.
Identities = 123/579 (21%), Positives = 192/579 (33%), Gaps = 60/579 (10%)
Query 54 CMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNI----QLTCNILTFG 109
+ I W + + +N F +L + G
Sbjct 3290 NIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENG 3349
Query 110 QLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEW-----DGGRETHLETNFTLKSEW 164
V + P P +++ IV +G + W DGG E K +
Sbjct 3350 TDTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLA--WKEPEDDGGAEISHYV--IEKQDA 3405
Query 165 ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDH-----INFDPVYK 219
AT ++ C +D T+ VD T + V+A N G I DP +
Sbjct 3406 ATGRWTACGESKD--TNFHVDDLTQGH-EYKFRVKAVNRHGDSDPLEAREAIIAKDPFDR 3462
Query 220 V-KPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDT 277
KP P + + L WT P+ I Y ++ RT + W +P
Sbjct 3463 ADKPGTPEIV-----DWDKDHADLKWTPPADDGGAPIEGYLVEMRTP-SGDW--VPAVTV 3514
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK-APSFWYKI 336
+ + TV LKP Y FR++ + + G+ SD S T +P AP +
Sbjct 3515 GAGELTATVDGLKPGQTYQFRVKALNKAGESTPSDPS-----RTMVAKPRHLAPKINRDM 3569
Query 337 DPS-HTQGYRT----VQLVWKTLPPFEA--NGKILDYEVTLTRWKSHLQNYTVNATKLTV 389
+ + +T V + + P E NG L + +H+ N T N TKLT
Sbjct 3570 FVAQRVKAGQTLNFDVNVEGEPAPKIEWFLNGSPLS-----SGGNTHIDNNTDNNTKLTT 3624
Query 390 NLT--NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
T D + N GK + V A + K K++++ ++W P
Sbjct 3625 KSTARADSGKYKIVATNESGKDEHEVDVNILDIPGAPEGPLRHKDITKESVV-LKWDEPL 3683
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
+ I + V +K W T + L+E Y V V G +P
Sbjct 3684 DDGGSPITNYVV--EKQEDGGRWVPCGETSDTSLKVNKLSEGHEYKFRVKAVNRQGTSAP 3741
Query 508 -ESIKAYLKQAP---PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
S A + + P P V K+ LEW P + I Y + + G
Sbjct 3742 LTSDHAIVAKNPFDEPDAPTDVTPVDWDKDHVDLEWKP-PANDGGAPIDAYIVEKKDKFG 3800
Query 564 NETA-VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
+ VD T+ T +LT Y R+ A G
Sbjct 3801 DWVECARVDGKTTKATADNLTPGETYQFRVKAVNKAGPG 3839
Score = 162 bits (410), Expect = 3e-39, Method: Composition-based stats.
Identities = 102/599 (17%), Positives = 180/599 (30%), Gaps = 62/599 (10%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINR-TASSVTFT 92
V++ + + + A + W N I + + I N S
Sbjct 2687 SDTTVKVGATLKFI-------VHIDGEPAPDVTWSFNGKGIGESKAQIENEPYISRFALP 2739
Query 93 D-IASLNIQLTCNILTFGQLEQNVYGITIISGLP--PEKPKNLSCIVNEGKKMRCEWDGG 149
+ + + T + I + S P P+ P ++ + + + W
Sbjct 2740 KALRKQSGKYTITATNINGTDSVTINIKVKS-KPTKPKGPIEVTDVFEDRATLD--WKPP 2796
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN-------IEVWVEAEN 202
+ E ++ K C T + V+ + V+A N
Sbjct 2797 EDDGGEPI-------EFYEIEKMNTKDGIWVPCGRSGDTHFTVDSLNKGDHYKFRVKAVN 2849
Query 203 ALGKVTSDHINFDPVYKVK-----PNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILK 256
+ G SD + + K P+ P ++ S + L W P S I +
Sbjct 2850 SEG--PSDPLETETDILAKNPFDRPDRPGRP--EPTDWDSDHVDLKWDPPLSDGGAPIEE 2905
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y I+ RTK W P +++ TV DL P EY FR+ + + G SD S+
Sbjct 2906 YQIEKRTKYGR-WE--PAITVPGGQTTATVPDLTPNEEYEFRVVAVNKGGPSDPSDASKA 2962
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
+P + Q V + + P + +
Sbjct 2963 VIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSGEPAPTVTWHWPD---NREIRNGGR 3019
Query 376 HLQNYTVNATKLTVNL--TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF 433
+ +KL V D T+ N G+ +A V + + +D+
Sbjct 3020 VKLDNPEYQSKLVVKQMERGDSGTFTIKAVNANGEDEATVKINVIDKPTSPNGPLDVSDV 3079
Query 434 PKDNMLWVEWTTPRES----VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
D+ + + W P + ++ Y++E D A + T + L
Sbjct 3080 HGDH-VTLNWRAPDDDGGIPIENYVIE---KYDTASGRWVPAAKVAGDKTTAVVDGLIPG 3135
Query 490 KCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP----TVRTKKVGKNEAVLEWDQLPVD 545
Y V V A+G P P P K+ LEW P +
Sbjct 3136 HEYKFRVAAVNAEGESDPLETFGTTLAKDPFDKPGKTNAPEITDWDKDHVDLEWKP-PAN 3194
Query 546 VQNGFIRNYTIFYRTIIGN--ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
I Y + + +V + T T+ +L + Y R+ A G D
Sbjct 3195 DGGAPIEEYVVEMKDEFSPFWNDVAHVPAGQTNATVGNLKEGSKYEFRIRAKNKAGLGD 3253
Score = 159 bits (401), Expect = 5e-38, Method: Composition-based stats.
Identities = 90/497 (18%), Positives = 160/497 (32%), Gaps = 37/497 (7%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETN--FTLKSEWATHKFADCKAKRDTPTSCT 183
P P+N++ WD ++ + ++ + + D + T+ T
Sbjct 4536 PGAPENITYPAVSRHTCTLNWDAPKDDGGAEIAGYKIEYQEVGSQIWDKVPGLISGTAYT 4595
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP-NPPHNLSVINSEELSS-ILK 241
V + + AENA+G SD+ PV P +PP S + +
Sbjct 4596 VRGLE-HGQQYRFRIRAENAVGL--SDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQVS 4652
Query 242 LTWTNP-SIKSVIILKYNI-QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
L W P IL Y + ++ + W+ + T V L Y FR+
Sbjct 4653 LAWNPPRDDGGSPILGYVVERFEKRGGGDWAPVKMPMVKGT--ECIVPGLHENETYQFRV 4710
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
R + G G S+ SE + Y ++P AP + L W P +
Sbjct 4711 RAVNAAGHGEPSNGSEPVTCRPYVEKP-GAPDAPRVGKITKNSAE----LTW-NRPLRDG 4764
Query 360 NGKILDYEVTLTRW----KSHLQNYTVNATKLTVNLT--NDRYLATLTVRNLVGKSDAAV 413
I Y V + + + V T V + Y + N G+ + +
Sbjct 4765 GAPIDGYIVEKKKLGDNDWTRCNDKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSK 4824
Query 414 LT-IPACDFQATHPVMDLKA-----FPKDNMLWVEWTTPRESVKKYILEWCVLSDK--AP 465
+ + + Q P+ D+ + + K I++ +
Sbjct 4825 PSDLVLIEEQPGRPIFDINNLKDITVRAGETIQIR-IPYAGGNPKPIIDLFNGNSPIFEN 4883
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
T G + T +++ Y I+ T Y + ++ AP +
Sbjct 4884 ERTVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGK---DTCKLNVFVLDAPGKPTGPI 4940
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
R + + L W P D I NY + RT G+ V T + +L ++
Sbjct 4941 RATDIQADAMTLSWRP-PKDNGGDAITNYVVEKRTPGGDWVTVGHPVG-TTLRVRNLDAN 4998
Query 586 TLYMVRMAAYTDEGGKD 602
T Y R+ A G +
Sbjct 4999 TPYEFRVRAENQYGVGE 5015
Score = 155 bits (392), Expect = 6e-37, Method: Composition-based stats.
Identities = 92/583 (16%), Positives = 178/583 (31%), Gaps = 40/583 (7%)
Query 36 PVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIIN-RTASSVTFTDI 94
+++ ++ ++ + W N + ++ I + +
Sbjct 2397 ITIKVGNDVEFDVPVRGE-------PPPKKEWIFNEKPVDDQKIRIESEDYKTRFVLRGA 2449
Query 95 ASLNIQLTCNILTFGQLEQNVYGITIISGLPPEK--PKNLSCIVNEGKKMRCEWDGGRET 152
+ L T I+ G P P +S + + + EW +
Sbjct 2450 TRKHAGLYTLTATNASGSDKHSVEVIVLGKPSSPLGPLEVSNVYEDRADL--EWKVPEDD 2507
Query 153 H---LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS 209
++ K + AT ++ C + +T + + + + V A N G+
Sbjct 2508 GGAPIDHYEIEKMDLATGRWVPC-GRSETTKTTVPNLQPGH--EYKFRVRAVNKEGESDP 2564
Query 210 DHINFDPVYKVKPNPPHNL-SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST 268
N + K P + + + L W P I + I+ + K+
Sbjct 2565 LTTNTAILAKNPYEVPGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGR- 2623
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
W + + + TV +LK EY FRI + G G SD S+ P
Sbjct 2624 WEEALV--VPGDQKTATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRI 2681
Query 329 APSFWYKIDPSHTQGYRTVQ-LVWKTLPPFEA--NGKILDYEVTLTRWKSHLQNYT-VNA 384
+ + + + P NGK + K+ ++N ++
Sbjct 2682 HREDLSDTTVKVGATLKFIVHIDGEPAPDVTWSFNGKGIG------ESKAQIENEPYISR 2735
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
L L T+T N+ G + +++ ++ ++W
Sbjct 2736 FALPKALRKQSGKYTITATNINGTDSVTINIKVKSKPTKPKGPIEVTDV-FEDRATLDWK 2794
Query 445 TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
P + +E+ + W + + +L + Y V V ++GP
Sbjct 2795 PPEDD-GGEPIEFYEIEKMNTKDGIWVPCGRSGDTHFTVDSLNKGDHYKFRVKAVNSEGP 2853
Query 505 GSPESIKAYLKQAPPSKGPTVRTKKVGKNE----AVLEWDQLPVDVQNGFIRNYTIFYRT 560
P + + P P + + L+WD P+ I Y I RT
Sbjct 2854 SDPLETETDILAKNPFDRPDRPGRPEPTDWDSDHVDLKWDP-PLSDGGAPIEEYQIEKRT 2912
Query 561 IIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
G A+ V T T+ LT + Y R+ A G D
Sbjct 2913 KYGRWEPAITVPGGQTTATVPDLTPNEEYEFRVVAVNKGGPSD 2955
Score = 149 bits (376), Expect = 4e-35, Method: Composition-based stats.
Identities = 85/491 (17%), Positives = 152/491 (31%), Gaps = 31/491 (6%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETH---LETNFTLKSEWATHKFADCKAKRDTPTSC 182
P P +S + + + W + +E K + AT ++ C +DT
Sbjct 2189 PNGPLEVSDVFED--NLNLSWKPPDDDGGEPIEYYEVEKLDTATGRWVPCAKVKDTKAHI 2246
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE-LSSILK 241
+ V+A N G + + D K + P + + + +
Sbjct 2247 DGLKKG---QTYQFRVKAVNKEGASDALSTDKDTKAKNPYDEPGKTGTPDVVDWDADRVS 2303
Query 242 LTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
L W P S I +Y I+ + K W + + +++ + LK EY FR++
Sbjct 2304 LEWEPPKSDGGAPITQYVIEKKGKHGRDWQECG--KVSGDQTNAEILGLKEGEEYQFRVK 2361
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEA 359
+ + G G SD S + +P I V + + P E
Sbjct 2362 AVNKAGPGEASDPSRKVVAKPRNLKPWIDREAMKTITIKVGNDVEFDVPVRGEPPPKKEW 2421
Query 360 --NGK-ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
N K + D ++ + + AT+ L TLT N G +V I
Sbjct 2422 IFNEKPVDDQKIRIESEDYKTRFVLRGATR------KHAGLYTLTATNASGSDKHSVEVI 2475
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
+ +++ ++ +EW P + I + + W +
Sbjct 2476 VLGKPSSPLGPLEVSNV-YEDRADLEWKVPEDDGGAPIDHYEIEKMDL-ATGRWVPCGRS 2533
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT----VRTKKVGK 532
NL Y V V +G P + + P + P K
Sbjct 2534 ETTKTTVPNLQPGHEYKFRVRAVNKEGESDPLTTNTAILAKNPYEVPGKVDKPELVDWDK 2593
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA-VNVDSSHTEYTLSSLTSDTLYMVR 591
+ L W+ D I + I + G + V T+ +L Y R
Sbjct 2594 DHVDLAWNA--PDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQKTATVPNLKEGEEYQFR 2651
Query 592 MAAYTDEGGKD 602
++A G D
Sbjct 2652 ISARNKAGTGD 2662
Score = 149 bits (375), Expect = 6e-35, Method: Composition-based stats.
Identities = 92/502 (18%), Positives = 158/502 (31%), Gaps = 22/502 (4%)
Query 109 GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH---LETNFTLKSEWA 165
G+ E V I P P ++S + + + W + +E K + A
Sbjct 3053 GEDEATVKINVIDKPTSPNGPLDVSDVHGDH--VTLNWRAPDDDGGIPIENYVIEKYDTA 3110
Query 166 THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPP 225
+ ++ T+ VD + V A NA G+ + K + P
Sbjct 3111 SGRWVPAAKVAGDKTTAVVDGLIPGH-EYKFRVAAVNAEGESDPLETFGTTLAKDPFDKP 3169
Query 226 HNLSV-INSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
+ ++ + L W P+ I +Y ++ + + + W+ + + +++
Sbjct 3170 GKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDEFSPFWNDVA--HVPAGQTN 3227
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
TV +LK ++Y FRIR + G G SD S A P + +I Q
Sbjct 3228 ATVGNLKEGSKYEFRIRAKNKAGLGDPSD-SASAVAKARNVPPVIDRNSIQEIKVKAGQD 3286
Query 344 YR-TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTV 402
+ + + + P V + L +D +
Sbjct 3287 FSLNIPVSGEPTPTIT--WTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKA 3344
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD 462
N G A V + +D+ KD + W P + I + +
Sbjct 3345 ENENGTDTAEVKVTVLDHPSSPRGPLDVTNIVKDGC-DLAWKEPEDDGGAEISHYVIEKQ 3403
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP----ESIKAYLKQAP 518
A W + + +L + Y V V G P E+I A
Sbjct 3404 DA-ATGRWTACGESKDTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEAREAIIAKDPFDR 3462
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET-AVNVDSSHTEY 577
K T K+ A L+W P D I Y + RT G+ AV V +
Sbjct 3463 ADKPGTPEIVDWDKDHADLKWTP-PADDGGAPIEGYLVEMRTPSGDWVPAVTVGAGELTA 3521
Query 578 TLSSLTSDTLYMVRMAAYTDEG 599
T+ L Y R+ A G
Sbjct 3522 TVDGLKPGQTYQFRVKALNKAG 3543
Score = 144 bits (363), Expect = 1e-33, Method: Composition-based stats.
Identities = 82/447 (18%), Positives = 133/447 (30%), Gaps = 33/447 (7%)
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYK----VKPNPPHNLSVINSEELSSILKLTWTN 246
+ V+A N G SD + + V P P N+ I+ + L W
Sbjct 1661 HGEYKFRVKALNECGL--SDPLTGESVLAKNPYGVPGKPKNMDAIDVD--KDHCTLAWEP 1716
Query 247 PSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P I Y I+ R K W Q+ T T + + EY++R++ + +
Sbjct 1717 PEEDGGAPITGYIIERREKSEKDWHQVG--QTKPDCCELTDKKVVEDKEYLYRVKAVNKA 1774
Query 306 GKGYWSDWSEEASGITYEDRPS-KAPSFWYKIDPSHTQGYRTVQLVWKTLPP--FEANGK 362
G G D + + P V + + LP + NGK
Sbjct 1775 GPGDPCDHGKPIKMKAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLWVVNGK 1834
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
L + ++ K+ + D T+T++N G D+
Sbjct 1835 PLKAVGRVKMSSERGKHIM----KIENAVRADSGKFTITLKNSSGSCDSTATVTVVGRPT 1890
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRES----VKKYILEWCVLSDKAPCITDWQQEDGTVH 478
+D+ D + W P + + YI+E D + + D
Sbjct 1891 PPKGPLDIADVCADGAT-LSWNPPDDDGGDPLTGYIVE-AQDMDNKGKYIEVGKVDPNTT 1948
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK----QAPPSKGPTVRTKKVGKNE 534
+ G L Y V V +G P S Y + P K +
Sbjct 1949 TLKVNG-LRNKGNYKFRVKAVNNEGESEPLSADQYTQIKDPWDEPGKPGRPEITDFDADR 2007
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
+ W+ D I Y + R E T ++S L Y R+ A
Sbjct 2008 IDIAWEPPHKD-GGAPIEEYIVEVRDPDTKEWKEVKRVPDTNASISGLKEGKEYQFRVRA 2066
Query 595 YTDEG-GKDG--PEFTFTTPKFAQGEI 618
G G+ E PKF +
Sbjct 2067 VNKAGPGQPSEPSEKQLAKPKFIPAWL 2093
Score = 136 bits (341), Expect = 6e-31, Method: Composition-based stats.
Identities = 92/564 (16%), Positives = 164/564 (29%), Gaps = 37/564 (7%)
Query 67 WKTNHFTIPKEQYTIINRTASSVTFTDIASLN----IQLTCNILTFGQLEQNVYGITIIS 122
WK N TI + T +S +++ + G+ +
Sbjct 3891 WKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYKIIVENEHGKDTAQCNVTVLDV 3950
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRE-THLETNFTLKSEWATHKFADCKAKRDTPTS 181
PE P L + W + + + + T + + P
Sbjct 3951 PGTPEGP--LKIDEIHKEGCTLNWKPPTDNGGTDVLHYIVEKMDTSRGTWQEVGT-FPDC 4007
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK-----PNPPHNLSVINSEEL 236
V V+A N G S + + K P+P V +
Sbjct 4008 TAKVNKLVPGKEYAFRVKAVNLQG--ESKPLEAEEPIIAKNQFDVPDPVDKPEVTD--WD 4063
Query 237 SSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+ + W + + Y ++ + K ++ W E + ++F+ +LKP EY
Sbjct 4064 KDRIDIKWNPTANNGGAPVTGYIVEKKEKGSAIW----TEAGKTPGTTFSADNLKPGVEY 4119
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG-YRTVQLVWKTL 354
FR+ + G SD S+ + R K G +++ +
Sbjct 4120 EFRVIAVNAAG---PSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGA 4176
Query 355 PPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVL 414
P A + D L + + D L V+N +G+ +A
Sbjct 4177 PDPTATWTVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGEDEAIFE 4236
Query 415 TIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED 474
I A +++ KD+ + + W P++ I + V T W
Sbjct 4237 VIVQDRPSAPEGPLEVSDVTKDSCV-LNWKPPKDDGGAEISNYVVEKRDTKTNT-WVPVS 4294
Query 475 GTVHRTYLRG-NLAESKCYLITVTPVYADGPGSP----ESIKAYLKQAPPSKGPTVRTKK 529
V T + L E Y V G E + A P K
Sbjct 4295 AFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKDPFGTPGKPGRPEIVD 4354
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYR-TIIGNETAVNVDSSH-TEYTLSSLTSDTL 587
+ ++WD P D + +Y I + G VN T ++ + +
Sbjct 4355 TDNDHIDIKWDP-PRDNGGSPVDHYDIERKDAKTGRWIKVNTSPVQGTAFSDTRVQKGHT 4413
Query 588 YMVRMAAYTDEG-GKDGPEFTFTT 610
Y R+ A G G+ T
Sbjct 4414 YEYRVVAVNKAGPGQPSDSSAAAT 4437
Score = 127 bits (319), Expect = 2e-28, Method: Composition-based stats.
Identities = 84/429 (20%), Positives = 133/429 (31%), Gaps = 34/429 (8%)
Query 197 WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IIL 255
+ A N G +D + + K KP P + ++ L W P I
Sbjct 2750 TITATNING---TDSVTINIKVKSKPTKPKGP-IEVTDVFEDRATLDWKPPEDDGGEPIE 2805
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y I+ W S + FTV L Y FR++ + +G S+
Sbjct 2806 FYEIEKMNTKDGIW----VPCGRSGDTHFTVDSLNKGDHYKFRVKAVNSEG------PSD 2855
Query 316 EASGIT--YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV----T 369
T P P + +P+ V L W P + I +Y++
Sbjct 2856 PLETETDILAKNPFDRPDRPGRPEPTDWDSDH-VDLKWDP-PLSDGGAPIEEYQIEKRTK 2913
Query 370 LTRWKSHLQNYTVNATKLTVNLT-NDRYLATLTVRNLVGKSDAA----VLTIPACDFQAT 424
RW+ + T +LT N+ Y + N G SD + + + +
Sbjct 2914 YGRWEPAITVPGGQTTATVPDLTPNEEYEFRVVAVNKGGPSDPSDASKAVIAKPRNLKPH 2973
Query 425 HPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW-CVLSDKAPCITDWQQEDGTVHRTYLR 483
LK + + P + W + + + ++ +
Sbjct 2974 IDRDALKNLTIKAGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVV 3033
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLP 543
+ T+ V A+G ++K + P S + V + L W P
Sbjct 3034 KQMERGDSGTFTIKAVNANGEDEA-TVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRA-P 3091
Query 544 VDVQNGFIRNYTI-FYRTIIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
D I NY I Y T G A V T + L Y R+AA EG
Sbjct 3092 DDDGGIPIENYVIEKYDTASGRWVPAAKVAGDKTTAVVDGLIPGHEYKFRVAAVNAEGES 3151
Query 602 DGPEFTFTT 610
D P TF T
Sbjct 3152 D-PLETFGT 3159
Score = 124 bits (312), Expect = 2e-27, Method: Composition-based stats.
Identities = 87/524 (17%), Positives = 154/524 (29%), Gaps = 45/524 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSC 182
PP P ++ W E T + ++ + +
Sbjct 5430 PPGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPE 5489
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
F + E V A NA GK + P + + S + +
Sbjct 5490 FTVDKLREFNDYEFRVVAINAAGKG------------IPSLPSGPIKIQESGGSRPQIVV 5537
Query 243 TWTNPSIK--SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
+ + + R + + W + E S+R F D Y F I+
Sbjct 5538 KPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASD----GVYKFTIK 5593
Query 301 CMKEDGKGYWS-DWSEEASGITYEDR-PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+ + G ++ + S T +AP K P+ + L +
Sbjct 5594 EVWDIDAGEYTVEVSNPYGSDTATANLVVQAPPVIEKDVPNTILPSGDLV----RLKIYF 5649
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT--------NDRYLATLTVRNLVGKSD 410
+ + + L R + + + T+ + ++ + TV N G++
Sbjct 5650 SGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEAT 5709
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW 470
+A + + + W P I + V +W
Sbjct 5710 TGFWLNVTGLPEAPQGPLHISNIGPSTAT-LSWRPPVTDGGSKITSYVVEKRDLSKD-EW 5767
Query 471 QQEDGTVHRT-YLRGNLAESKCYLITVTPVYADGPGSP----ESIKAYLKQAPPSKGPTV 525
V Y+ L E+ Y V+ +G G+P I A L PP+ +
Sbjct 5768 VTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPLNL 5827
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLT 583
+VG + L W Q P+ G +R Y + + +E S Y + +L
Sbjct 5828 EIVQVGGDYVTLSW-QRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPSPPNNYNVPNLI 5886
Query 584 SDTLYMVRMAAYTDEGGKDGPEFTFTT-PKFAQGEIEAIVVPVC 626
Y R+ A D G D E T GE IV P+
Sbjct 5887 DGRKYRYRVFAVNDAGLSDLAELDQTLFQASGSGEGPKIVSPLS 5930
Score = 123 bits (307), Expect = 6e-27, Method: Composition-based stats.
Identities = 92/542 (17%), Positives = 161/542 (30%), Gaps = 49/542 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P +P+ + + EWD R+ + T AK D C
Sbjct 5330 VPNQPEAPTVRDKDSTWAELEWDPPRDGGSKIIGYQVQYRDTSSGRWINAKMDLSEQCHA 5389
Query 185 DYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYK---VKPNPPHNLSVINSEELSSIL 240
+ + E + A+NA G + K P PP ++ +
Sbjct 5390 RVTGLRQNGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPPIHVGAKSIGRN--HC 5447
Query 241 KLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+TW P I YN++ R ++ W+ D FTV L+ F +Y FR+
Sbjct 5448 TITWMAPLEDGGSKITGYNVEIREYGSTLWT--VASDYNVREPEFTVDKLREFNDYEFRV 5505
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL--PPF 357
+ GKG S S ++ P K + + R + + P
Sbjct 5506 VAINAAGKGIPSLPSGPIKI---QESGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEP 5562
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
A E+ + + V + D T+ V N G A +
Sbjct 5563 TARWLRNGRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSNPYGSDTATANLVV 5622
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
P + K P P + + + + + + ++E
Sbjct 5623 Q------APPVIEKDVPNT-------ILPSGDLVRLKIYFSGTAPFRHSLVLNREEIDMD 5669
Query 478 HRTYLRGNLAESKC-------------YLITVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
H T + Y TV+ + L +AP +GP
Sbjct 5670 HPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEATTGFWLNVTGLPEAP--QGP- 5726
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAVNVDSSHTEYTLSSLT 583
+ +G + A L W PV I +Y + R + V + Y ++ L
Sbjct 5727 LHISNIGPSTATLSWRP-PVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKDMNYIVTGLF 5785
Query 584 SDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFN 642
+ Y R++A + G G P A+ + P+ L + V +
Sbjct 5786 ENHEYEFRVSAQNENGIGAPLVSEH---PIIARLPFDPPTSPLNLEIVQVGGDYVTLSWQ 5842
Query 643 KR 644
+
Sbjct 5843 RP 5844
Score = 122 bits (306), Expect = 8e-27, Method: Composition-based stats.
Identities = 99/564 (18%), Positives = 173/564 (31%), Gaps = 55/564 (10%)
Query 75 PKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQ-NVYGITIISGLPPE------ 127
P E+Y I RT I Q T + E+ + + G P +
Sbjct 2902 PIEEYQIEKRTKYGRWEPAITVPGGQTTATVPDLTPNEEYEFRVVAVNKGGPSDPSDASK 2961
Query 128 ----KPKNLSCIVNEGKKMRCEWDGGRETHLET------NFTLKSEWATHKFADCKAKRD 177
KP+NL ++ G+ + T+ W ++ +
Sbjct 2962 AVIAKPRNLKPHIDRDALKNLTIKAGQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVK 3021
Query 178 TPTSCTVDYSTVYFV----NIEVWVEAENALGKVTSDHINFDPVYKVKPNPP-HNLSVIN 232
V + + ++A NA G+ D KP P L V +
Sbjct 3022 LDNPEYQSKLVVKQMERGDSGTFTIKAVNANGE---DEATVKINVIDKPTSPNGPLDVSD 3078
Query 233 SEELSSILKLTWTNPSIKSVIILK-YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ L W P I ++ Y I+ + W +P A +++ V L P
Sbjct 3079 VHG--DHVTLNWRAPDDDGGIPIENYVIEKYDTASGRW--VPAAKVAGDKTTAVVDGLIP 3134
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
EY FR+ + +G+ SD E G T P P + + V L W
Sbjct 3135 GHEYKFRVAAVNAEGE---SDPLE-TFGTTLAKDPFDKPGKTNAPEITDWDKDH-VDLEW 3189
Query 352 KTLPPFEANGKILDYEVT----LTRWKSHLQNYTVNATKLTVNLTND--RYLATLTVRNL 405
K P + I +Y V + + + + + T TV + +Y + +N
Sbjct 3190 KP-PANDGGAPIEEYVVEMKDEFSPFWNDVAHVPAGQTNATVGNLKEGSKYEFRIRAKNK 3248
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAF-------PKDNMLWVEWTTPRESVKKYILEWC 458
G D + + PV+D + +D L + I
Sbjct 3249 AGLGDPSDSASAVAKARNVPPVIDRNSIQEIKVKAGQDFSLNI---PVSGEPTPTITWTF 3305
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ + + +++ L I + +G + E +K + P
Sbjct 3306 EGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYI-IKAENENGTDTAE-VKVTVLDHP 3363
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
S + + K+ L W + P D I +Y I + +S T +
Sbjct 3364 SSPRGPLDVTNIVKDGCDLAWKE-PEDDGGAEISHYVIEKQDAATGRWTACGESKDTNFH 3422
Query 579 LSSLTSDTLYMVRMAAYTDEGGKD 602
+ LT Y R+ A G D
Sbjct 3423 VDDLTQGHEYKFRVKAVNRHGDSD 3446
Score = 121 bits (303), Expect = 2e-26, Method: Composition-based stats.
Identities = 61/333 (18%), Positives = 102/333 (31%), Gaps = 22/333 (7%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTL-KSEWATHKFADCKA 174
I + P P+++ W TN+ + K + K
Sbjct 5221 IRLKVVDKPASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGKWEKV 5280
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK---PNPPHNLSVI 231
+ V AE G + V K + PN P +V
Sbjct 5281 SSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVVVAKYQFEVPNQPEAPTVR 5340
Query 232 NSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ + S+ +L W P I+ Y +QYR + W I + S + V L+
Sbjct 5341 DKD--STWAELEWDPPRDGGSKIIGYQVQYRDTSSGRW--INAKMDLSEQCHARVTGLRQ 5396
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
E+ FRI G S SE + P + + G + W
Sbjct 5397 NGEFEFRIIAKNAAGFSKPSPPSERCQLKSRFGPPGPP-----IHVGAKSIGRNHCTITW 5451
Query 352 KTLPPFEANGKILDYEVTLTRWKSHL----QNYTVNATKLTVNLTN--DRYLATLTVRNL 405
P + KI Y V + + S L +Y V + TV+ + Y + N
Sbjct 5452 MA-PLEDGGSKITGYNVEIREYGSTLWTVASDYNVREPEFTVDKLREFNDYEFRVVAINA 5510
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
GK ++ + P ++ + P+D
Sbjct 5511 AGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTA 5543
Score = 106 bits (265), Expect = 6e-22, Method: Composition-based stats.
Identities = 71/492 (14%), Positives = 141/492 (29%), Gaps = 38/492 (8%)
Query 126 PEKPKNLSCIVN-EGKKMRCEWDGGRETHLE--TNFTL-KSEWATHKFADCKAKRDTPTS 181
PE P+ I N W T++ + K + + ++ +
Sbjct 5720 PEAPQGPLHISNIGPSTATLSWRPPVTDGGSKITSYVVEKRDLSKDEWVTVTSNVKDMN- 5778
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHN-LSVINSEELSSIL 240
+ E V A+N G + ++ +PP + L++ + +
Sbjct 5779 -YIVTGLFENHEYEFRVSAQNENGIGAPLVSEHPIIARLPFDPPTSPLNLEIVQVGGDYV 5837
Query 241 KLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
L+W P S + Y ++ + ++ W + S +++ V +L +Y +R+
Sbjct 5838 TLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCN--QNPSPPNNYNVPNLIDGRKYRYRV 5895
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
+ + G SD +E + + P + + + R V
Sbjct 5896 FAVNDAGL---SDLAELDQTLFQASGSGEGPKIVSPLSDLNEEVGRCVTF---------- 5942
Query 360 NGKILDYEVTLTRWKSHLQNYTVNATKLTVN------------LTNDRYLATLTVRNLVG 407
+I RW + + +N ++D T N G
Sbjct 5943 ECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQVLIINDLTSDDADEYTCRATNSSG 6002
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
+ P + +E P ++ + W +K
Sbjct 6003 TRSTRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARWTKDGEKIENN 6062
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
+ + T N + V V + GS P
Sbjct 6063 SKFSITTDDKFATLRISNASREDYGEYRV--VVENSVGSDSGTVNVTVADVPEPPRFPII 6120
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTL 587
+ + +L W P + NYTI R +G + S +T T+ L +
Sbjct 6121 ENILDEAVILSWKP-PALDGGSLVTNYTIEKREAMGGSWSPCAKSRYTYTTIEGLRAGKQ 6179
Query 588 YMVRMAAYTDEG 599
Y R+ A G
Sbjct 6180 YEFRIIAENKHG 6191
Score = 102 bits (254), Expect = 1e-20, Method: Composition-based stats.
Identities = 64/388 (16%), Positives = 119/388 (31%), Gaps = 29/388 (7%)
Query 230 VINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
+ + L L W P + Y I+ + + W+++ + + F V+D
Sbjct 1602 LETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEMQEGRSGNWAKVG----ETKGTDFKVKD 1657
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR-PSKAPSFWYKIDPSHTQGYRTV 347
LK EY FR++ + E G S+ +G + + P P +D
Sbjct 1658 LKEHGEYKFRVKALNECGL------SDPLTGESVLAKNPYGVPGKPKNMDAIDVDKDHC- 1710
Query 348 QLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT------NDRYLATLT 401
L W+ P + I Y + + LT + YL +
Sbjct 1711 TLAWEP-PEEDGGAPITGYIIERREKSEKDWHQVGQTKPDCCELTDKKVVEDKEYLYRVK 1769
Query 402 VRNLVGKSDA----AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
N G D + + A +K +++ P W
Sbjct 1770 AVNKAGPGDPCDHGKPIKMKAKKASPEFTGGGIKDLRLKVGETIKYDVPISGEPLPECLW 1829
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
V + + N + T+T + G + + +
Sbjct 1830 VVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTITLKNSSGSCDSTATVTVVGRP 1889
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV---NVDSSH 574
P KGP + V + A L W+ P D + Y + + + + VD +
Sbjct 1890 TPPKGP-LDIADVCADGATLSWNP-PDDDGGDPLTGYIVEAQDMDNKGKYIEVGKVDPNT 1947
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
T ++ L + Y R+ A +EG +
Sbjct 1948 TTLKVNGLRNKGNYKFRVKAVNNEGESE 1975
Score = 78.7 bits (192), Expect = 2e-13, Method: Composition-based stats.
Identities = 40/214 (19%), Positives = 65/214 (30%), Gaps = 8/214 (4%)
Query 394 DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKY 453
D L + N G + A + ++ K + + V W TP
Sbjct 1568 DTGKWALELGNSAGTALAPFELFVKDKPKPPKGPLETKNVTAEGLDLV-WGTPDPDEGAP 1626
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP---ESI 510
+ + + + +W + T + +L E Y V + G P ES+
Sbjct 1627 VKAYIIEMQEGRS-GNWAKVGETKGTDFKVKDLKEHGEYKFRVKALNECGLSDPLTGESV 1685
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAV 568
A P K + V K+ L W+ P + I Y I R +
Sbjct 1686 LAKNPYGVPGKPKNMDAIDVDKDHCTLAWEP-PEEDGGAPITGYIIERREKSEKDWHQVG 1744
Query 569 NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
E T + D Y+ R+ A G D
Sbjct 1745 QTKPDCCELTDKKVVEDKEYLYRVKAVNKAGPGD 1778
Score = 73.0 bits (177), Expect = 1e-11, Method: Composition-based stats.
Identities = 69/478 (14%), Positives = 125/478 (26%), Gaps = 43/478 (9%)
Query 68 KTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCN-ILTFGQLEQNVYGI-------- 118
K + + K + + D+ + L N F QN GI
Sbjct 5751 KITSYVVEKRDLSKDEWVTVTSNVKDMNYIVTGLFENHEYEFRVSAQNENGIGAPLVSEH 5810
Query 119 TIISGLP---PEKPKNLSCIVNEGKKMRCEWDGGRETH---LETNFTLKSEWATHKFADC 172
II+ LP P P NL + G + W L K E ++ C
Sbjct 5811 PIIARLPFDPPTSPLNLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRC 5870
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
P + + + V A N G SD D +++
Sbjct 5871 NQNPSPPNN-YNVPNLIDGRKYRYRVFAVNDAGL--SDLAELDQTLFQASGSGEGPKIVS 5927
Query 233 S-----EELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
EE+ + I +Y ++ + + +
Sbjct 5928 PLSDLNEEVGRCVTF---ECEISGSPRPEYR-WFKGCKELVDTSKYTLINKGDKQVLIIN 5983
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR-T 346
DL + R G + + + +P Y +G
Sbjct 5984 DLTSDDADEYTCRATNSSGTRS------TRANLRIKTKPRVFIPPKYHGGYEAQKGETIE 6037
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLV 406
+++ +K P EA ++ S + +++ D + V N V
Sbjct 6038 LKIPYKAYPQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRVVVENSV 6097
Query 407 GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
G SD+ + + D P + D + + W P + + + +A
Sbjct 6098 G-SDSGTVNVTVADVP-EPPRFPIIENILDEAVILSWKPPALDGGSLVTNYTIEKREAMG 6155
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
W + + L K Y + G P + P P
Sbjct 6156 -GSWSPCAKSRYTYTTIEGLRAGKQYEFRIIAENKHGQSKP------CEPTAPVLIPG 6206
Score = 72.6 bits (176), Expect = 2e-11, Method: Composition-based stats.
Identities = 38/258 (15%), Positives = 79/258 (31%), Gaps = 29/258 (11%)
Query 193 NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKS 251
E V EN++G SD + P PP I L + L+W P+
Sbjct 6086 YGEYRVVVENSVG---SDSGTVNVTVADVPEPPRFP--IIENILDEAVILSWKPPALDGG 6140
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT-VQDLKPFTEYVFRIRCMKEDGKGYW 310
++ Y I+ R +WS A +R ++T ++ L+ +Y FRI + G+
Sbjct 6141 SLVTNYTIEKREAMGGSWS-----PCAKSRYTYTTIEGLRAGKQYEFRIIAENKHGQSKP 6195
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT------VQLVWKTLPPFEANGKIL 364
+ + E + + + +G + V +WK
Sbjct 6196 CEPTAPVLIPGDERKRRRGYDVDEQGKIVRGKGTVSSNYDNYVFDIWK-----------Q 6244
Query 365 DYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
Y + H+ ++ +L + T + + +
Sbjct 6245 YYPQPVEIKHDHVLDHYDIHEELGTGAFGVVHRVTERATGNNFAAKFVMTPHESDKETVR 6304
Query 425 HPVMDLKAFPKDNMLWVE 442
+ + ++ +
Sbjct 6305 KEIQTMSVLRHPTLVNLH 6322
>sp|Q99715|COCA1_HUMAN Collagen alpha-1(XII) chain OS=Homo sapiens
OX=9606 GN=COL12A1 PE=1 SV=2
Length=3063
Score = 173 bits (438), Expect = 1e-42, Method: Composition-based stats.
Identities = 95/534 (18%), Positives = 158/534 (30%), Gaps = 53/534 (10%)
Query 82 INRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKK 141
++R+ +S + D+ S T ++ ++ + P P NL +
Sbjct 1612 VDRSETSTSLKDLFS-QTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEG 1670
Query 142 MRCEWDGGRETHLETNFT---LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
R WD G T S + + + EV +
Sbjct 1671 FRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPN------TIYEVSI 1724
Query 199 EAENALGKVTSDHI----NFDPVYKVKPNP-PHNLSVINSEELSSILKLTWTNPSIKSVI 253
A + D I + P P NL V S+ L + W S
Sbjct 1725 TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQV--YNATSNSLTVKWDP---ASGR 1779
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ KY I Y+ Q ++S +Q LKP T Y + + DG+G
Sbjct 1780 VQKYRITYQPSTGEGNEQTTT--IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGG---- 1833
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
G T +P DPS + T+ + W A G Y++
Sbjct 1834 RMTGRGKT---KPLNTVRNLRVYDPSTS----TLNVRWD-----HAEGNPRQYKLFYAPA 1881
Query 374 KSHLQN---YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
+ N + T+TV + + D +
Sbjct 1882 AGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQ 1941
Query 431 KAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
P N L V W V +Y + + + P + R L
Sbjct 1942 VYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSES---IVVPGNTRMVHLERLIPDT 1998
Query 491 CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
Y + + +Y+DG G+P + P S +R N + WD +G
Sbjct 1999 LYSVNLVALYSDGEGNPSPAQGRT--LPRSGPRNLRVFGETTNSLSVAWDH-----ADGP 2051
Query 551 IRNYTIFYRTIIGN--ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
++ Y I Y +G+ + V L L DT Y + + A ++G
Sbjct 2052 VQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105
Score = 168 bits (426), Expect = 3e-41, Method: Composition-based stats.
Identities = 82/493 (17%), Positives = 151/493 (31%), Gaps = 62/493 (13%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
E P NL + R W ++ + + KR ++
Sbjct 1386 EAPSNLVISERTHRSFRVSWTPPSDSV--------DRYKVEYYPVSGGKRQEFYVSRMET 1437
Query 187 STVYF-----VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
STV V V V D + K P +S+ + + +
Sbjct 1438 STVLKDLKPETEYVVNVY------SVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMH 1491
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+ W + Y + Y+ + ++ T + + DL P TEY ++
Sbjct 1492 VQWQPVGGATG----YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQA 1547
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ D SE + P P D +H+ T+ + W+ +P G
Sbjct 1548 VLHDLT------SEPVTVR-EVTLPLPRPQDLKLRDVTHS----TMNVFWEPVP-----G 1591
Query 362 KILDYEVTLTRWKSHLQNY----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
K+ Y V + ++ + +T L + Y +++ + G+S +T
Sbjct 1592 KVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPP--VTAQ 1649
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
P W V Y + W +
Sbjct 1650 ETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSD----KMETILNGD 1705
Query 478 HRTYLRGNLAESKCYLITVTPVYADGP------GSPESIKAYLKQAPPSKGPTVRTKKVG 531
T + NL + Y +++T +Y D GS ++ QAP S ++
Sbjct 1706 ENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNAT 1765
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRT--IIGNETAVNVDSSHTEYTLSSLTSDTLYM 589
N ++WD +G ++ Y I Y+ GNE + L L DT Y
Sbjct 1766 SNSLTVKWDP-----ASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYT 1820
Query 590 VRMAAYTDEGGKD 602
+ +++ +G
Sbjct 1821 ITVSSLYPDGEGG 1833
Score = 167 bits (422), Expect = 1e-40, Method: Composition-based stats.
Identities = 106/526 (20%), Positives = 169/526 (32%), Gaps = 54/526 (10%)
Query 98 NIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN 157
I ++EQ + I + +P PK+LS + W E +
Sbjct 607 RISFELTQSICLRIEQELAAIKKKAYVP---PKDLSFSEVTSYGFKTNWSPAGENVFSYH 663
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPV 217
T K + + T + V V AE G S + +
Sbjct 664 ITYKEAAGDDEVTVVEPASSTSVVLSSLKPETL---YLVNVTAEYEDG--FSIPLAGEET 718
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
+ P NL V + E + K+TWT +L+Y I YR ++ T
Sbjct 719 TEEVKGAPRNLKVTD--ETTDSFKITWT---QAPGRVLRYRIIYRPVAGGESREVT---T 770
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
+ T+++L P T+Y + G G +G + P D
Sbjct 771 PPNQRRRTLENLIPDTKYEVSVIPEYFSGPGT------PLTGNAATEEVRGNPRDLRVSD 824
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ-----NYTVNATKLTVNLT 392
P+ + T++L W P GK+ Y VT T T L
Sbjct 825 PTTS----TMKLSWSGAP-----GKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKE 875
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
+Y ++T G D A+ + P + D + WT+ V+
Sbjct 876 GTQYALSVTALYASGAGD-ALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRG 934
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
Y + W L D T + T + NL Y I+V Y+ G G P + A
Sbjct 935 YRVSWKSLYDD--VDTGEKNLPEDAIHTMI-ENLQPETKYRISVFATYSSGEGEPLTGDA 991
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT-IIGNETAVNVD 571
+ + SK T++ + +N + W P G + NY + YR G + V
Sbjct 992 TTELSQDSK--TLKVDEETENTMRVTWKPAP-----GKVVNYRVVYRPHGRGKQMVAKVP 1044
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEG------GKDGPEFTFTTP 611
+ T L L T Y + + G G F +P
Sbjct 1045 PTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSP 1090
Score = 156 bits (394), Expect = 2e-37, Method: Composition-based stats.
Identities = 99/552 (18%), Positives = 181/552 (33%), Gaps = 63/552 (11%)
Query 76 KEQYTIINRTASSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSC 134
K Q ++R +S D+ + + + + + G +P +S
Sbjct 1426 KRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVP-----VVSL 1480
Query 135 IVNE--GKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF 191
+ + M +W G T ++ K T + + + V
Sbjct 1481 NIYDVGPTTMHVQWQPVGGATGYILSY--KPVKDTEPTRPKEVRLGPTVNDMQLTDLVPN 1538
Query 192 VNIEVWVEAENALGKVTSDHINFDPVYKVKPNP-PHNLSVINSEELSSILKLTWTNPSIK 250
V V+A L +TS+ + P P P +L + + S + + W
Sbjct 1539 TEYAVTVQAV--LHDLTSEPVTVR--EVTLPLPRPQDLKL--RDVTHSTMNVFWEP---V 1589
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
+ KY ++Y+T + + + + +S +++DL T Y + + ++G+
Sbjct 1590 PGKVRKYIVRYKTPE----EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGE--- 1642
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S + RP AP+ + + T W + Y +T
Sbjct 1643 ---SPPVTAQ-ETTRPVPAPTNLKITEVTSEGFRGT----WD-----HGASDVSLYRITW 1689
Query 371 TRWKS-----HLQNYTVNATKLTVNLTNDRYLATLTV-RNLVGKSD---AAVLTIPACDF 421
+ S + N N N Y ++T +SD + T+P
Sbjct 1690 APFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTT 1749
Query 422 QAT-HPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
QA +L+ + N L V+W V+KY + + + + T G
Sbjct 1750 QAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT---TTIGGRQN 1806
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
+ + L Y ITV+ +Y DG G + + K + +R + + W
Sbjct 1807 SVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL--NTVRNLRVYDPSTSTLNVRW 1864
Query 540 DQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
D G R Y +FY G E V + + L +L DT Y V + E
Sbjct 1865 DH-----AEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTE 1919
Query 599 GGKDGPEFTFTT 610
G T T
Sbjct 1920 GDGGRTSDTGRT 1931
Score = 155 bits (390), Expect = 7e-37, Method: Composition-based stats.
Identities = 92/540 (17%), Positives = 163/540 (30%), Gaps = 68/540 (13%)
Query 80 TIINRTASSVTFTDIAS---LNIQLTCNILTFGQLEQNVYGIT-----IISGLPPEKPKN 131
TI+N +++ F ++ + +T I ++ G + + P P+N
Sbjct 1700 TILNGDENTLVFENLNPNTIYEVSITA-IYPDESESDDLIGSERTLPILTTQAPKSGPRN 1758
Query 132 LSCIVNEGKKMRCEWDG--GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
L + +WD GR + + + +T + + + V
Sbjct 1759 LQVYNATSNSLTVKWDPASGRV----QKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLK 1814
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNP---PHNLSVINSEELSSILKLTWTN 246
+ V + G+ + K P NL V + +S L + W +
Sbjct 1815 PDTPYTITVSSLYPDGEGG------RMTGRGKTKPLNTVRNLRVYDP--STSTLNVRWDH 1866
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR-CMKED 305
+Y + Y +P + +++L+P T Y + E
Sbjct 1867 AE---GNPRQYKLFYAPAAGGPEELVP---IPGNTNYAILRNLQPDTSYTVTVVPVYTEG 1920
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G SD +G T +P+ ++ + W P G +L
Sbjct 1921 DGGRTSD-----TGRTLM---RGLARNVQVYNPT----PNSLDVRWDPAP-----GPVLQ 1963
Query 366 YEVTLTRWKSH--LQNYTVNAT----KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
Y V + ++ V L + + Y L G+ + +
Sbjct 1964 YRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS--PAQGR 2021
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ P N L V W V++Y + + I ++ G +
Sbjct 2022 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD--PIDEYTTVPGRRNN 2079
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
L+ L Y ITV VY DG G + P + + W
Sbjct 2080 VILQ-PLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLP--PQNIHISDEWYTRFRVSW 2136
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
D P + Y I Y+ + NE T YTL +L T Y V + A D G
Sbjct 2137 DPSP-----SPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSG 2191
Score = 142 bits (357), Expect = 7e-33, Method: Composition-based stats.
Identities = 79/485 (16%), Positives = 149/485 (31%), Gaps = 56/485 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWD--GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P+NL + W GR + + + + +R
Sbjct 724 GAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLE--- 780
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ + EV V E G + + + P +L V + +S +KL+W
Sbjct 781 --NLIPDTKYEVSVIPEYFSG--PGTPLTGNAATEEVRGNPRDLRVSDP--TTSTMKLSW 834
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
S + +Y + Y ++ ++ +Q LK T+Y + +
Sbjct 835 ---SGAPGKVKQYLVTYTPVAGGETQEVTVR---GDTTNTVLQGLKEGTQYALSVTALYA 888
Query 305 DGKG--YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
G G + + G T E+R +P D + T ++ W + P G
Sbjct 889 SGAGDALFGE------GTTLEER--GSPQDLVTKDITDT----SIGAYWTSAP-----GM 931
Query 363 ILDYEVTLTRW----KSHLQNYTVN--ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
+ Y V+ + +N + T + +Y ++ G+ + LT
Sbjct 932 VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEP--LTG 989
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
A + +N + V W V Y + + + + T
Sbjct 990 DATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVA---KVPPT 1046
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAV 536
V T L+ L Y ITV P+Y G G + ++T +
Sbjct 1047 VTSTVLK-RLQPQTTYDITVLPIYKMGEGKLRQGSGTTA-SRFKSPRNLKTSDPTMSSFR 1104
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNET--AVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
+ W+ P G ++ Y + + + + V L L + T Y V +
Sbjct 1105 VTWEPAP-----GEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFG 1159
Query 595 YTDEG 599
D G
Sbjct 1160 MFDGG 1164
Score = 123 bits (309), Expect = 4e-27, Method: Composition-based stats.
Identities = 82/540 (15%), Positives = 147/540 (27%), Gaps = 49/540 (9%)
Query 76 KEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCI 135
EQ T I +SV + + T + + + P +NL
Sbjct 1795 NEQTTTIGGRQNSVVLQKLK-PDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVY 1853
Query 136 VNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIE 195
+ WD + L A + T+ + + +
Sbjct 1854 DPSTSTLNVRWD--HAEGNPRQYKLFYAPAAGGPEELVP-IPGNTNYAILRNLQPDTSYT 1910
Query 196 VWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
V V G + + N+ V N + L + W +L
Sbjct 1911 VTVVPVYTEGDGGRTSDTGRTLMRGLA---RNVQVYNP--TPNSLDVRWDP---APGPVL 1962
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+Y + Y D + S+ ++ L P T Y + + DG+G S
Sbjct 1963 QYRVVYSPVDGTRPSESIV--VPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS---- 2016
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
A G T P P + ++ + W A+G + Y + +
Sbjct 2017 PAQGRTL---PRSGPRNLRVFGETTN----SLSVAWD-----HADGPVQQYRIIYSPTVG 2064
Query 376 ----HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
+ + +TV + D LT P
Sbjct 2065 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHI 2124
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
+ V W V Y + + + P + G + L NL S
Sbjct 2125 SDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEP----MEAFVGEMTSYTLH-NLNPSTT 2179
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
Y + V Y G P + + + ++T ++G + ++W
Sbjct 2180 YDVNVYAQYDSGLSVPLTDQGTTLYLNVT---DLKTYQIGWDTFCVKWSPHRA------A 2230
Query 552 RNYTIFYRTIIG-NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+Y + G + V S T + + L+ DT Y V + T G T
Sbjct 2231 TSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHT 2290
Score = 117 bits (292), Expect = 4e-25, Method: Composition-based stats.
Identities = 57/281 (20%), Positives = 103/281 (37%), Gaps = 15/281 (5%)
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT 399
+ +R+ ++ W K+ Y V+ + + + +T L Y+
Sbjct 1394 SERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVN 1453
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWC 458
+ D + + PV+ L + + V+W + YIL +
Sbjct 1454 VYSVV----EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGAT-GYILSYK 1508
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ D P + TV+ L +L + Y +TV V D P +++ P
Sbjct 1509 PVKDTEPTRPKEVRLGPTVNDMQL-TDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLP 1567
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
+ ++ + V + + W+ +P G +R Y + Y+T + V VD S T +
Sbjct 1568 --RPQDLKLRDVTHSTMNVFWEPVP-----GKVRKYIVRYKTPEEDVKEVEVDRSETSTS 1620
Query 579 LSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEI 618
L L S TLY V ++A DEG T P A +
Sbjct 1621 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNL 1661
Score = 103 bits (255), Expect = 9e-21, Method: Composition-based stats.
Identities = 54/314 (17%), Positives = 97/314 (31%), Gaps = 28/314 (9%)
Query 351 WKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL-----TNDRYLATLTVRNL 405
W A + Y +T + V T + YL +T
Sbjct 652 WSP-----AGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYE 706
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAP 465
G S + + + + D+ + WT V +Y + + ++
Sbjct 707 DGFSIPLAGEETTEEVKGAPRNLKVTDETTDS-FKITWTQAPGRVLRYRIIYRPVAGGES 765
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
+ R NL Y ++V P Y GPG+P + A ++ +
Sbjct 766 R----EVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVR-GNPRDL 820
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET-AVNVDSSHTEYTLSSLTS 584
R + L W P G ++ Y + Y + G ET V V T L L
Sbjct 821 RVSDPTTSTMKLSWSGAP-----GKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKE 875
Query 585 DTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAI---VVPVCLAFLLTTLLGVLFCF 641
T Y + + A G D TT + + + + + T+ G++ +
Sbjct 876 GTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGY 935
Query 642 NKRDLIKKHIWPNV 655
K ++ +V
Sbjct 936 RVS---WKSLYDDV 946
Score = 45.6 bits (106), Expect = 0.003, Method: Composition-based stats.
Identities = 13/87 (15%), Positives = 30/87 (34%), Gaps = 7/87 (8%)
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT--IIGNETAV 568
+ + + +V L W+ P + Y + + A+
Sbjct 326 ELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSP-----SPVTGYKVILTPMTAGSRQHAL 380
Query 569 NVDSSHTEYTLSSLTSDTLYMVRMAAY 595
+V T ++ L++DT Y + ++A
Sbjct 381 SVGPQTTTLSVRDLSADTEYQISVSAM 407
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 20/81 (25%), Positives = 29/81 (36%), Gaps = 7/81 (9%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
PP NL I E S +KL W + Y + A + +
Sbjct 335 EPPSNL--IAMEVSSKYVKLNWNP---SPSPVTGYKVILTPMTAGSRQH--ALSVGPQTT 387
Query 283 SFTVQDLKPFTEYVFRIRCMK 303
+ +V+DL TEY + MK
Sbjct 388 TLSVRDLSADTEYQISVSAMK 408
Score = 45.2 bits (105), Expect = 0.004, Method: Composition-based stats.
Identities = 20/82 (24%), Positives = 35/82 (43%), Gaps = 8/82 (10%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
+PP +L+ +E + ++W P I+ Y I T D +T +++ +
Sbjct 26 DPPSDLNFKIIDEN--TVHMSWAKPVDP---IVGYRI---TVDPTTDGPTKEFTLSASTT 77
Query 283 SFTVQDLKPFTEYVFRIRCMKE 304
+ +L P TEYV I E
Sbjct 78 ETLLSELVPETEYVVTITSYDE 99
Score = 42.9 bits (99), Expect = 0.019, Method: Composition-based stats.
Identities = 35/239 (15%), Positives = 76/239 (32%), Gaps = 26/239 (11%)
Query 75 PKEQYTIINRTASSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLS 133
P ++YT + ++V + ++T + ++ G GL P P+N+
Sbjct 2066 PIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLP--PQNIH 2123
Query 134 CIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN 193
+ R WD L K + + + T ++ ST Y VN
Sbjct 2124 ISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVN 2183
Query 194 IEVWVEAENALGKVTSDH---INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
V+ + ++ L +D + + + + + W+
Sbjct 2184 --VYAQYDSGLSVPLTDQGTTLYLNVTD-----------LKTYQIGWDTFCVKWSPHRAA 2230
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ Y ++ D + +I + +S L P T+Y + + +G
Sbjct 2231 TS----YRLKLSPADGTRGQEITVR---GSETSHCFTGLSPDTDYGVTVFVQTPNLEGP 2282
Score = 41.8 bits (96), Expect = 0.038, Method: Composition-based stats.
Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 4/100 (4%)
Query 418 ACDFQATHPVMDLKAFPKDNM-LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
+ P +L A + + + W V Y + +L+ G
Sbjct 328 VSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKV---ILTPMTAGSRQHALSVGP 384
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
T +L+ Y I+V+ + P SI +
Sbjct 385 QTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQP 424
>sp|Q2VWP7|PRTG_HUMAN Protogenin OS=Homo sapiens OX=9606 GN=PRTG
PE=2 SV=1
Length=1150
Score = 170 bits (430), Expect = 5e-42, Method: Composition-based stats.
Identities = 103/617 (17%), Positives = 198/617 (32%), Gaps = 64/617 (10%)
Query 20 STGELLDPCGYIS-PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQ 78
+T +L P ++ PES VC + + + W N I
Sbjct 319 ATLTVLAPPSFVEWPESLTRPRAGTARFVC-------QAEGIPSPKMSWLKNGRKIHSNG 371
Query 79 YTIINRTASSVTFTDIASLNIQLTCNILTF-GQLEQNVYGITIISGLPPEKPKNLSCIVN 137
+ + + I + C G + ++S P P N+
Sbjct 372 RIKMYNSKLVIN-QIIPEDDAIYQCMAENSQGSILSRARLTVVMSEDRPSAPYNVHAETM 430
Query 138 EGKKMRCEWDGG-----RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV 192
+ W+ + ++ +K+E ++ DT D
Sbjct 431 SSSAILLAWERPLYNSDKVIAYSVHY-MKAEGLNNEEYQVVIGNDTTHYIIDDLEPA--S 487
Query 193 NIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW--TNPSI 249
N ++ A +G SDH+ + + V PP + + + + ++W
Sbjct 488 NYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPPE---ISLTSRSPTDILISWLPIPAKY 544
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ ++ Y + +R ++ I + T + ++ LKP + Y+ RI G G
Sbjct 545 RRGQVVLYRLSFRLSTENS---IQVLELPGTTHEYLLEGLKPDSVYLVRITAATRVGLGE 601
Query 310 WSDWSEEASGITYEDRPSKAP-SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
S W S T + KAP S ++P T+ + W+ E I Y++
Sbjct 602 SSVW---TSHRTPKATSVKAPKSPELHLEP---LNCTTISVRWQQ--DVEDTAAIQGYKL 653
Query 369 TLTRWKSHLQNYTVNATK-----LTVNLTNDRYLATLTVRNLVGK--------SDAAVLT 415
TK L+ +Y L N + S ++
Sbjct 654 YYKEEGQQENGPIFLDTKDLLYTLSGLDPRRKYHVRLLAYNNIDDGYQADQTVSTPGCVS 713
Query 416 IPACDFQATHPVMDLKA-FPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQ 471
+ P L A + +++ W P + Y + + + + +
Sbjct 714 VRDRMVPPPPPPHHLYAKANTSSSIFLHWRRPAFTAAQIINYTIRCNPVGLQNASLVLYL 773
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYAD--GPGSPESIKAYLKQAPPSKGPTVRTKK 529
Q T L L + Y V P SP + L +AP V+
Sbjct 774 Q---TSETHMLVQGLEPNTKYEFAVRLHVDQLSSPWSPVVYHSTLPEAPAGPPVGVKVTL 830
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT----IIGNETAVNVDSSHTEYTLSSLTSD 585
+ + A++ W P D + YTI Y + I G ++ + + T L +L +
Sbjct 831 IEDDTALVSWK--PPDGPETVVTRYTILYASRKAWIAGEWQVLHREGAITMALLENLVAG 888
Query 586 TLYMVRMAAYTDEGGKD 602
+Y+V+++A + G
Sbjct 889 NVYIVKISASNEVGEGP 905
Score = 120 bits (301), Expect = 2e-26, Method: Composition-based stats.
Identities = 53/312 (17%), Positives = 105/312 (34%), Gaps = 37/312 (12%)
Query 319 GITYEDRPS--------KAPSFWYKIDPSHTQGYRTVQLVW-KTLPPFEANGKILDYEVT 369
+T PS P +G + ++ W K +NG+I Y
Sbjct 320 TLTVLAPPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKMYN-- 377
Query 370 LTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDA-AVLTIPACDFQATHP 426
+KL +N + D + N G + A LT+ + + + P
Sbjct 378 ---------------SKLVINQIIPEDDAIYQCMAENSQGSILSRARLTVVMSEDRPSAP 422
Query 427 VMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
+ + + W P + V Y + + + + ++Q G Y+
Sbjct 423 YNVHAETMSSSAILLAWERPLYNSDKVIAYSVHY--MKAEGLNNEEYQVVIGNDTTHYII 480
Query 484 GNLAESKCYLITVTPVYADG-PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
+L + Y + G + + + P + P + + ++ W +
Sbjct 481 DDLEPASNYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPPEISLTSRSPTDILISWLPI 540
Query 543 PVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
P + G + Y + +R N + + + EY L L D++Y+VR+ A T G
Sbjct 541 PAKYRRGQVVLYRLSFRLSTENSIQVLELPGTTHEYLLEGLKPDSVYLVRITAATRVGLG 600
Query 602 DGP-EFTFTTPK 612
+ + TPK
Sbjct 601 ESSVWTSHRTPK 612
Score = 111 bits (278), Expect = 1e-23, Method: Composition-based stats.
Identities = 57/312 (18%), Positives = 104/312 (33%), Gaps = 29/312 (9%)
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
+ + EDRPS + + T + L W+ P + K++ Y V + +
Sbjct 410 LTVVMSEDRPSAPYNVH-----AETMSSSAILLAWE--RPLYNSDKVIAYSVHYMKAEGL 462
Query 377 LQN-----YTVNATKLTVNLTNDR--YLATLTVRNLVGKSDAA--VLTIPACDFQATHPV 427
+ T ++ Y + +G S + V D P
Sbjct 463 NNEEYQVVIGNDTTHYIIDDLEPASNYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPPE 522
Query 428 MDLKAFPKDNMLWVEWTT-PRESVKKYILEWCVLSD-KAPCITDWQQEDGTVHRTYLRGN 485
+ L + + + W P + + ++ + + + GT H YL
Sbjct 523 ISLTS-RSPTDILISWLPIPAKYRRGQVVLYRLSFRLSTENSIQVLELPGTTHE-YLLEG 580
Query 486 LAESKCYLITVTPVYADGPGSPESIKA-YLKQA----PPSKGPTVRTKKVGKNEAVLEWD 540
L YL+ +T G G + +A P P + + + + W
Sbjct 581 LKPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAPKS-PELHLEPLNCTTISVRWQ 639
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
Q D I+ Y ++Y+ E + +D+ YTLS L Y VR+ AY +
Sbjct 640 QDVEDTAA--IQGYKLYYKEEGQQENGPIFLDTKDLLYTLSGLDPRRKYHVRLLAYNNID 697
Query 600 GKDGPEFTFTTP 611
+ T +TP
Sbjct 698 DGYQADQTVSTP 709
Score = 89.1 bits (219), Expect = 1e-16, Method: Composition-based stats.
Identities = 53/326 (16%), Positives = 98/326 (30%), Gaps = 32/326 (10%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRE-THLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P+ P+ L + W E T + L + + + DT
Sbjct 619 PKSPE-LHLEPLNCTTISVRWQQDVEDTAAIQGYKLYYKEEGQQ-ENGPIFLDTKDLLYT 676
Query 185 DYSTVYFVNIEVWVEAENALG------KVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
V + A N + + S ++ P PP + SS
Sbjct 677 LSGLDPRRKYHVRLLAYNNIDDGYQADQTVSTPGCVSVRDRMVPPPPPPHHLYAKANTSS 736
Query 239 ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ L W P+ + I+ Y I+ S + T + + VQ L+P T+Y F
Sbjct 737 SIFLHWRRPAFTAAQIINYTIRCNPVGLQNASLVLYLQT--SETHMLVQGLEPNTKYEFA 794
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+R + S WS T + P+ P T + WK E
Sbjct 795 VRLHVDQ---LSSPWSPVVYHSTLPEAPAGPP----VGVKVTLIEDDTALVSWKPPDGPE 847
Query 359 ANGKILDYEVTL--------TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD 410
+ Y + W+ + + L + + Y+ ++ N VG+
Sbjct 848 TV--VTRYTILYASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVKISASNEVGEGP 905
Query 411 AA----VLTIPACDFQATHPVMDLKA 432
+ + +P ++ L +
Sbjct 906 FSNSVELAVLPKETSESNQRPKRLDS 931
>sp|Q9EQS9|IGDC4_MOUSE Immunoglobulin superfamily DCC subclass
member 4 OS=Mus musculus OX=10090 GN=Igdcc4 PE=2 SV=1
Length=1252
Score = 168 bits (426), Expect = 2e-41, Method: Composition-based stats.
Identities = 101/624 (16%), Positives = 176/624 (28%), Gaps = 75/624 (12%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
PE+ S VC + W + + + S+ T
Sbjct 340 PEALSRTRASTARFVC-------RASGEPRPALHWLHDGIPLRPNGRVKVQGGGGSLVIT 392
Query 93 DIASLNI-QLTCNILTFGQLE--QNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGG 149
I + C + + GL P P ++ + W+
Sbjct 393 QIGLQDAGYYQCVAENSAGTACAAAPLAVVVREGL-PSAPTRVTATPLSSSSVLVAWERP 451
Query 150 RETHLETN-FTLKSEWA-THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG-K 206
+ F+L + A + + + T+ + E +V A + LG
Sbjct 452 ELHSEQIIGFSLHYQKARGVDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGAS 511
Query 207 VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN--PSIKSVIILKYNIQYRTK 264
TS + V P + S S +++ W S+ + +LKY I+Y
Sbjct 512 RTSSPALVHTLDDVPSAAPQ---LTLSSPNPSDIRVAWLPLPSSLSNGQVLKYKIEY--- 565
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
Q+ + + T+ L+P Y RI G G S W + + +
Sbjct 566 GLGKEDQVFSTEVPGNETQLTLNSLQPNKVYRVRISAGTGAGYGVPSQWMQHRTPGVHNQ 625
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT--- 381
S P ++ ++ + W+ P I Y++ + +
Sbjct 626 --SHVPFAPAELKVRA--KMESLVVSWQPPPHPTQ---ISGYKLYWREVGTEEEADGDRP 678
Query 382 -------------------VNATKLTVNLTNDRYLATLTVRNL---------VGKSD-AA 412
V +LT + Y L N GK++ A
Sbjct 679 PGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAP 738
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITD 469
+P P +W+ W P + Y + + + +
Sbjct 739 TPDLPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFGPWGLRNASLVT 798
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITV--TPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
+ G L G L Y V V DGP ++ L P + +R
Sbjct 799 YYTSSG---EDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRL 855
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY----RTIIGNETAVNVDSSHTEYTLSSLT 583
+ + L W P NG I Y I Y T + + + + L
Sbjct 856 SPLTPSTVRLHW--CPPTEPNGEIVEYLILYSNNHTQPEHQWTLLTTEGNIFSAEVHGLE 913
Query 584 SDTLYMVRMAAYTDEGGKDGPEFT 607
SDT Y +M A T+ G
Sbjct 914 SDTRYFFKMGARTEVGPGPFSRLQ 937
>sp|Q91145|COCA1_NOTVI Collagen alpha-1(XII) chain (Fragment)
OS=Notophthalmus viridescens OX=8316 PE=2 SV=1
Length=929
Score = 167 bits (422), Expect = 4e-41, Method: Composition-based stats.
Identities = 112/540 (21%), Positives = 170/540 (31%), Gaps = 48/540 (9%)
Query 69 TNHFTIPKEQYTIINRTASSVTFTDIASLN-IQLTCNILTFGQLEQNVYGITIISGLPPE 127
+ E T D + I + ++EQ + I + S P
Sbjct 10 KDAVRSELEAIATPPTATHVYTVEDFDAFQRISFELTQSIWLRIEQELKSIKVKSLTP-- 67
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
P++LS R W E + +F PT+ TV +
Sbjct 68 -PRDLSFAEVTSSSFRVSWSPAAEDAIAYLVNYTVALGGEEFV---VSVPAPTTSTVLTN 123
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP 247
EV V AE G S + + P NL V + E + K+ WT
Sbjct 124 LFPKTTYEVRVVAEYPEG--ESPPLKGEETTLEVRGAPRNLRVTD--ETTDSFKVGWTP- 178
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
+L+Y I YR ++ + + + +L P T+Y + G
Sbjct 179 --APGNVLRYRIAYRPVAGGERKEVTVQGNERATTLY---NLFPDTKYHVSGVPEYQSGP 233
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY- 366
G +G + P +P+ + ++L W P GK+ Y
Sbjct 234 GT------ALNGNGATEEVVGEPKNLRVSEPTTST---AMRLTWDKAP-----GKVQRYL 279
Query 367 -EVTLTRWKSHLQNYTVNA-TKLTVNLTNDRYLATLTVRNLVGKS-DAAVLTIPACDFQA 423
+ ++ TV T TV D A N + S +T Q
Sbjct 280 RNLHSRSAGGDIKEVTVKGDTSTTVLKELDPGTAYTLSVNPLYASGAGTAVTGEGATLQE 339
Query 424 THPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
DL D + WT V+ Y + W L D T G T L
Sbjct 340 RGSPRDLIIKDITDTTIGTSWTAAPGMVRGYRIAWQSLFDDK---TGENHVPGDTTNTVL 396
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
R NL Y ++V YA G G P S +A + +P G V+ + + W
Sbjct 397 R-NLDPETKYRLSVYANYASGEGDPLSGEATTEASP--DGKIVKISEETETTMKATWQPA 453
Query 543 PVDVQNGFIRNYTIFYRT-IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
P G + NY + YR G + V + T L LT T Y + + EG
Sbjct 454 P-----GNVLNYRVVYRPRAGGRQIVAKVPPAVTSTVLRRLTPLTTYDISVIPVYKEGDG 508
Score = 132 bits (332), Expect = 3e-30, Method: Composition-based stats.
Identities = 73/439 (17%), Positives = 138/439 (31%), Gaps = 48/439 (11%)
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+ + +W+ E L + + PP +LS +E SS +++W+ +
Sbjct 43 FELTQSIWLRIEQELKSIKVKSLT----------PPRDLS--FAEVTSSSFRVSWSPAAE 90
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ + Y + Y + + +S + +L P T Y R+ +G+
Sbjct 91 DA---IAYLVNYTVALGGEEFVV---SVPAPTTSTVLTNLFPKTTYEVRVVAEYPEGE-- 142
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
S G AP D + + ++ W P G +L Y +
Sbjct 143 ----SPPLKGEETTLEVRGAPRNLRVTDETTD----SFKVGWTPAP-----GNVLRYRIA 189
Query 370 LTRWKSHLQ---NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
+ N T+ ++ L +
Sbjct 190 YRPVAGGERKEVTVQGNERATTLYNLFPDTKYHVSGVPEYQSGPGTALNGNGATEEVVGE 249
Query 427 VMDLKAFP--KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
+L+ + + W V++Y+ + S A G T L+
Sbjct 250 PKNLRVSEPTTSTAMRLTWDKAPGKVQRYLRN--LHSRSAGGDIKEVTVKGDTSTTVLKE 307
Query 485 NLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
L Y ++V P+YA G G+ + + Q + K + W P
Sbjct 308 -LDPGTAYTLSVNPLYASGAGTAVTGEGATLQER-GSPRDLIIKDITDTTIGTSWTAAP- 364
Query 545 DVQNGFIRNYTIFYRTIIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
G +R Y I ++++ ++T +V T L +L +T Y + + A G D
Sbjct 365 ----GMVRGYRIAWQSLFDDKTGENHVPGDTTNTVLRNLDPETKYRLSVYANYASGEGDP 420
Query 604 PEFTFTTPKFAQGEIEAIV 622
TT G+I I
Sbjct 421 LSGEATTEASPDGKIVKIS 439
Score = 128 bits (321), Expect = 6e-29, Method: Composition-based stats.
Identities = 75/483 (16%), Positives = 147/483 (30%), Gaps = 45/483 (9%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
P+NL + W L + + + T+ +
Sbjct 157 GAPRNLRVTDETTDSFKVGWTPAPGNVLRYRIAYRPVAGGERKEVTVQGNERATTLYNLF 216
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ V +N + + P NL V + S+ ++LTW
Sbjct 217 PDTKY-----HVSGVPEYQSGPGTALNGNGATEEVVGEPKNLRV-SEPTTSTAMRLTWDK 270
Query 247 PSIKSVIILKY--NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ +Y N+ R+ I S+ +++L P T Y + +
Sbjct 271 ---APGKVQRYLRNLHSRSAGGD----IKEVTVKGDTSTTVLKELDPGTAYTLSVNPLYA 323
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
G G + G T ++R +P D + T + W P G +
Sbjct 324 SGAGT----AVTGEGATLQER--GSPRDLIIKDITDTTIGTS----WTAAP-----GMVR 368
Query 365 DYEVTLTRW---KSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
Y + K+ + + T + + L+V + L+ A
Sbjct 369 GYRIAWQSLFDDKTGENHVPGDTTNTVLRNLDPETKYRLSVYANYASGEGDPLSGEATTE 428
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
+ + + + + W +V Y + + + + + V T
Sbjct 429 ASPDGKIVKISEETETTMKATWQPAPGNVLNYRVVYRPRAGGRQIVA---KVPPAVTSTV 485
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
LR L Y I+V PVY +G G +P + +++T + ++ + W+
Sbjct 486 LR-RLTPLTTYDISVIPVYKEGDGKTRQGSGTTL-SPFNAPRSIKTSEPTRSTFRVTWEP 543
Query 542 LPVDVQNGFIRNYTIFYRT--IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
P G ++ Y I + G + V + L L + T Y V + D+G
Sbjct 544 AP-----GEVKGYKITFHPEGDDGYLGEMMVGPYDSTVVLEELRARTSYKVNVFGVFDDG 598
Query 600 GKD 602
Sbjct 599 QSP 601
Score = 58.3 bits (139), Expect = 3e-07, Method: Composition-based stats.
Identities = 23/120 (19%), Positives = 41/120 (34%), Gaps = 6/120 (5%)
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
P + + P V W P +SV+++ +E+ ++ P + GT
Sbjct 816 PGGLNPPSNLVTSEPTPRSFRVTWVPPSQSVERFKVEYYPVAGGRPQEVYVR---GTQTT 872
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
T L G L Y + V V +G E + P + +G ++W
Sbjct 873 TVLVG-LKPETEYYVNVYSV--EGNEISEPLAGTETTLPIPSVRNMNLYDIGTTTMRVKW 929
Score = 57.2 bits (136), Expect = 6e-07, Method: Composition-based stats.
Identities = 70/517 (14%), Positives = 139/517 (27%), Gaps = 69/517 (13%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
K + M+ W L + + AK + TV
Sbjct 434 KIVKISEETETTMKATWQPAPGNVLNYRVVYRPRAGGRQIV---AKVPPAVTSTVLRRLT 490
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHN--LSVINSEELSSILKLTWTNP 247
++ V G + + + P N S+ SE S ++TW
Sbjct 491 PLTTYDISVIPVYKEGDGKTRQGSGTTLS------PFNAPRSIKTSEPTRSTFRVTWEP- 543
Query 248 SIKSVIILKYNIQYRTKDASTW---SQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ Y I + + + + P D S+ +++L+ T Y + + +
Sbjct 544 --APGEVKGYKITFHPEGDDGYLGEMMVGPYD-----STVVLEELRARTSYKVNVFGVFD 596
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL--VWKTLPPFEANGK 362
DG+ S T D P + Q + + W N K
Sbjct 597 DGQ---SPPLIGHETTTLRDAPRSPIPSSGLDCTTKAQADIVLLVDGSW---SIGRPNFK 650
Query 363 ILDYEVT------------LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD 410
I+ ++ + S +L + T + + G +
Sbjct 651 IVRNFISRVVEVFDIGSDRVQIAVSQYSGDPRTEWQLNTHKTKKSLMDAVANLPYKGGNT 710
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW 470
+ P + ++ + + + ++ + + + +
Sbjct 711 NTGSALKFILENNFRPGVGMREKARKIAILLTDGKSQDDIVAPSKRYADEGIELYAV-GI 769
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTP-------VYADGPGSPESIKAYLKQAPPSKGP 523
+ D + + Y+ V V S+K PPS
Sbjct 770 KNADENELKEIASD---PDELYMYNVADFSLLTNIVNDLTENVCNSVKGPGGLNPPS--- 823
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSL 582
+ T + + W + + + +Y G V V + T L L
Sbjct 824 NLVTSEPTPRSFRVTWVPPSQS-----VERFKVEYYPVAGGRPQEVYVRGTQTTTVLVGL 878
Query 583 TSDTLYMVRMAAYTDEGGK-----DGPEFTFTTPKFA 614
+T Y V + Y+ EG + G E T P
Sbjct 879 KPETEYYVNV--YSVEGNEISEPLAGTETTLPIPSVR 913
Score = 53.7 bits (127), Expect = 9e-06, Method: Composition-based stats.
Identities = 28/129 (22%), Positives = 52/129 (40%), Gaps = 19/129 (15%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
NPP NL + SE ++TW PS + ++ ++Y ++ T++
Sbjct 820 NPPSNL--VTSEPTPRSFRVTWVPPSQS---VERFKVEYYPVAGGRPQEVYVR---GTQT 871
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
+ + LKP TEY + ++ + + SE +G T P + D
Sbjct 872 TTVLVGLKPETEYYVNVYSVEGN------EISEPLAG-TETTLPIPSVRNMNLYD----I 920
Query 343 GYRTVQLVW 351
G T+++ W
Sbjct 921 GTTTMRVKW 929
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 23/131 (18%), Positives = 39/131 (30%), Gaps = 11/131 (8%)
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGK 532
T Y + + +T + + P + +V
Sbjct 23 PPTATHVYTVEDFDAFQRISFELT----QSIWLRIEQELKSIKVKSLTPPRDLSFAEVTS 78
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYR-TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
+ + W D Y + Y + G E V+V + T L++L T Y VR
Sbjct 79 SSFRVSWSPAAED-----AIAYLVNYTVALGGEEFVVSVPAPTTSTVLTNLFPKTTYEVR 133
Query 592 MAAYTDEGGKD 602
+ A EG
Sbjct 134 VVAEYPEGESP 144
>sp|Q2EY15|PRTG_MOUSE Protogenin OS=Mus musculus OX=10090 GN=Prtg
PE=2 SV=1
Length=1191
Score = 167 bits (422), Expect = 5e-41, Method: Composition-based stats.
Identities = 107/617 (17%), Positives = 197/617 (32%), Gaps = 64/617 (10%)
Query 20 STGELLDPCGYIS-PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQ 78
+T +L P ++ PES VC + + + W N I
Sbjct 313 ATLTVLAPPSFVEWPESLTRPRAGTARFVC-------QAEGIPSPKMSWLKNGRRIHSNG 365
Query 79 YTIINRTASSVTFTDIASLNIQLTCNILTF-GQLEQNVYGITIISGLPPEKPKNLSCIVN 137
+ + + I + C G + ++S P P N+
Sbjct 366 RIKMYNSKLVIN-QIIPEDDAIYQCMAENSQGSVLSRARLTVVMSEDRPSAPYNVHAETM 424
Query 138 EGKKMRCEWDGG-----RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV 192
+ W+ + ++ +K+E ++ DT D
Sbjct 425 SSSAILLAWERPLYNSDKVIAYSVHY-MKAEGLNNEEYQVVLGNDTTHYIIDDLEPD--S 481
Query 193 NIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW--TNPSI 249
N ++ A LG SDH+ + + V PP + + + + ++W
Sbjct 482 NYTFYIVAYMPLGASQMSDHVTQNTLEDVPLRPPE---ISLTSRSPTDILVSWLPIPAKY 538
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ ++ Y + +R ST + I + T + ++ LKP + Y+ RI G G
Sbjct 539 RRGQVVLYRLSFRL---STENAIQVVELPGTVHEYLLEGLKPDSVYLVRITAATRVGLGE 595
Query 310 WSDWSEEASGITYEDRPSKAP-SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
S W S T + KAP S ++P T+ + W L E I Y++
Sbjct 596 SSVW---TSHRTPKATSVKAPKSPELHLEP---LNCTTISVRW--LQDTEDPAAIRGYKL 647
Query 369 TLTRWKSHLQNYTVNAT-----KLTVNLTNDRYLATLTVRNLV--GKSDAAVLTIPACDF 421
T L+ +Y L N + G ++ P C
Sbjct 648 FYKEEGQQEHGPIFLDTGDLLYTLSGLDPRRKYHVRLLAYNNMEEGYQADQTVSTPGCVS 707
Query 422 QATHPVMDLKAFPK-------DNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQ 471
V + +++ W P V Y + + + + +
Sbjct 708 VRDRMVPPPPPPHHLYAKANTSSSIFLHWRRPAFTTAQVINYTIRCNPVGLQNASLVLYL 767
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYAD--GPGSPESIKAYLKQAPPSKGPTVRTKK 529
Q T L L + Y V P SP + L +AP V+
Sbjct 768 Q---TSETHMLVQGLEPNTKYEFAVRLHVDQLSSPWSPVVYHSTLPEAPTGPPVGVKVTL 824
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT----IIGNETAVNVDSSHTEYTLSSLTSD 585
+ + A++ W P D + YTI Y + I G ++ + + T L +L +
Sbjct 825 IEDDTALVSWK--PPDGPETVVTRYTILYASRKAWIAGEWQVLHREGAITMALLENLVAG 882
Query 586 TLYMVRMAAYTDEGGKD 602
+Y+V+++A + G
Sbjct 883 NVYIVKISASNEVGEGP 899
Score = 119 bits (298), Expect = 5e-26, Method: Composition-based stats.
Identities = 87/616 (14%), Positives = 180/616 (29%), Gaps = 82/616 (13%)
Query 32 SPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTI-PKEQYTIINRTASSVT 90
P+ V C + + W N + ++ +++ + ++
Sbjct 38 EPQDATVTRKDPVVLDCQAHGE-------GPIKVTWLKNGAKLSENKRIQVLSNGSLYIS 90
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITII-------SGLPPEKPKNLSCIVNEGK--K 141
+ L N YG + S + + +S V+EG +
Sbjct 91 EVEGRRGEQSDEGFYQC---LAVNKYGAILSQKAHLTLSTISAFEVHPVSTEVHEGGVAR 147
Query 142 MRC----------EWDGGRETHLETNFTLKSEWATH--KFADCKAKRDTPTSCTVDYSTV 189
C W+ R T L T + + + D + C
Sbjct 148 FSCKISSTPPAVITWEFNR-TALPTTMDRVTALPSGVLQIYDVGPEDAGNYRCVAATIAH 206
Query 190 YFVNIE--VWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP 247
++E + + A N I P + + ++W+
Sbjct 207 KRKSMEASLTIVAANETRSFYMPTIIASPQNVTASLH-QTVVLECMATGYPRPIISWS-- 263
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT-EYVFRIRCMKEDG 306
+ I +N + S + + T P T + + +
Sbjct 264 RLDHKSIDVFNTRVLGNGNLIISDVKLQHAGVYVCRAT----TPGTRNFTVAMATLTVLA 319
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW-KTLPPFEANGKILD 365
+ +W E + P +G + ++ W K +NG+I
Sbjct 320 PPSFVEWPESLTR----------PRAGTARFVCQAEGIPSPKMSWLKNGRRIHSNGRIKM 369
Query 366 YEVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDA-AVLTIPACDFQ 422
Y +KL +N + D + N G + A LT+ + +
Sbjct 370 YN-----------------SKLVINQIIPEDDAIYQCMAENSQGSVLSRARLTVVMSEDR 412
Query 423 ATHPVMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ P + + + W P + V Y + + + + ++Q G
Sbjct 413 PSAPYNVHAETMSSSAILLAWERPLYNSDKVIAYSVHY--MKAEGLNNEEYQVVLGNDTT 470
Query 480 TYLRGNLAESKCYLITVTPVYADG-PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
Y+ +L Y + G + + + P + P + + ++
Sbjct 471 HYIIDDLEPDSNYTFYIVAYMPLGASQMSDHVTQNTLEDVPLRPPEISLTSRSPTDILVS 530
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
W +P + G + Y + +R N V + + EY L L D++Y+VR+ A T
Sbjct 531 WLPIPAKYRRGQVVLYRLSFRLSTENAIQVVELPGTVHEYLLEGLKPDSVYLVRITAATR 590
Query 598 EGGKDGP-EFTFTTPK 612
G + + TPK
Sbjct 591 VGLGESSVWTSHRTPK 606
Score = 109 bits (272), Expect = 5e-23, Method: Composition-based stats.
Identities = 104/623 (17%), Positives = 184/623 (30%), Gaps = 94/623 (15%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
+ P S V C I W+ N +P + + +
Sbjct 133 VHPVSTEVHEGGVARFSC-------KISSTPPAVITWEFNRTALPTTMDRVTALPSGVLQ 185
Query 91 FTDIASLNI-QLTCNILTFGQLEQN-------VYGITIISGLPP---EKPKNLSCIVNEG 139
D+ + C T ++ V S P P+N++ +++
Sbjct 186 IYDVGPEDAGNYRCVAATIAHKRKSMEASLTIVAANETRSFYMPTIIASPQNVTASLHQT 245
Query 140 KKMRC----------EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
+ C W ++ T +D K + C
Sbjct 246 VVLECMATGYPRPIISWSRLDHKSIDVFNTRVLGNGNLIISDVKLQHAGVYVCRATTPGT 305
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS- 248
+ + L + P +P V +E + S K++W
Sbjct 306 RNFTVAMAT-----LTVLAPPSFVEWPESLTRPRAGTARFVCQAEGIPS-PKMSWLKNGR 359
Query 249 --IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ I YN + +QI PED A +++ G
Sbjct 360 RIHSNGRIKMYNSKLVI------NQIIPEDDA-----------------IYQCMAENSQG 396
Query 307 KGYWSDWSEEASGITY-EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
S S + EDRPS + + T + L W+ P + K++
Sbjct 397 ----SVLSRARLTVVMSEDRPSAPYNVH-----AETMSSSAILLAWE--RPLYNSDKVIA 445
Query 366 YEVTLTRWKS-HLQNYTV----NATKLTVNLTN--DRYLATLTVRNLVGKSDAA--VLTI 416
Y V + + + + Y V + T ++ Y + +G S + V
Sbjct 446 YSVHYMKAEGLNNEEYQVVLGNDTTHYIIDDLEPDSNYTFYIVAYMPLGASQMSDHVTQN 505
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTT-PRESVKKYILEWCVLSD-KAPCITDWQQED 474
D P + L + + V W P + + ++ + + +
Sbjct 506 TLEDVPLRPPEISLTS-RSPTDILVSWLPIPAKYRRGQVVLYRLSFRLSTENAIQVVELP 564
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA-YLKQA----PPSKGPTVRTKK 529
GTVH YL L YL+ +T G G + +A P P + +
Sbjct 565 GTVHE-YLLEGLKPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAPKS-PELHLEP 622
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSDTLY 588
+ + W Q IR Y +FY+ E + +D+ YTLS L Y
Sbjct 623 LNCTTISVRWLQ--DTEDPAAIRGYKLFYKEEGQQEHGPIFLDTGDLLYTLSGLDPRRKY 680
Query 589 MVRMAAYTDEGGKDGPEFTFTTP 611
VR+ AY + + T +TP
Sbjct 681 HVRLLAYNNMEEGYQADQTVSTP 703
Score = 88.8 bits (218), Expect = 1e-16, Method: Composition-based stats.
Identities = 43/261 (16%), Positives = 82/261 (31%), Gaps = 29/261 (11%)
Query 194 IEVWVEAENAL------GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP 247
V + A N + + S ++ P PP + SS + L W P
Sbjct 680 YHVRLLAYNNMEEGYQADQTVSTPGCVSVRDRMVPPPPPPHHLYAKANTSSSIFLHWRRP 739
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
+ + ++ Y I+ S + T + + VQ L+P T+Y F +R +
Sbjct 740 AFTTAQVINYTIRCNPVGLQNASLVLYLQT--SETHMLVQGLEPNTKYEFAVRLHVDQ-- 795
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
S WS T + P+ P T + WK E + Y
Sbjct 796 -LSSPWSPVVYHSTLPEAPTGPP----VGVKVTLIEDDTALVSWKPPDGPETV--VTRYT 848
Query 368 VTL--------TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA----VLT 415
+ W+ + + L + + Y+ ++ N VG+ + +
Sbjct 849 ILYASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVKISASNEVGEGPFSNSVELAV 908
Query 416 IPACDFQATHPVMDLKAFPKD 436
+P ++ L +
Sbjct 909 LPKDASESNQRPKRLDSSNAK 929
Score = 73.7 bits (179), Expect = 7e-12, Method: Composition-based stats.
Identities = 31/194 (16%), Positives = 68/194 (35%), Gaps = 5/194 (3%)
Query 136 VNEGKKMRCEWDGGRETHLET-NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNI 194
N + W T + N+T++ + A T + +
Sbjct 726 ANTSSSIFLHWRRPAFTTAQVINYTIRCNPVGLQNASLVLYLQTSETHMLVQGLEPNTKY 785
Query 195 EVWVEA-ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI 253
E V + L S + + + PP + V E+ ++++ +W P +
Sbjct 786 EFAVRLHVDQLSSPWSPVVYHSTLPEAPTGPPVGVKVTLIEDDTALV--SWKPPDGPETV 843
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ +Y I Y ++ A + + +++L Y+ +I E G+G +S+
Sbjct 844 VTRYTILYASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVKISASNEVGEGPFSN- 902
Query 314 SEEASGITYEDRPS 327
S E + + + S
Sbjct 903 SVELAVLPKDASES 916
>sp|Q8TDY8|IGDC4_HUMAN Immunoglobulin superfamily DCC subclass
member 4 OS=Homo sapiens OX=9606 GN=IGDCC4 PE=1 SV=1
Length=1250
Score = 167 bits (422), Expect = 6e-41, Method: Composition-based stats.
Identities = 102/624 (16%), Positives = 175/624 (28%), Gaps = 75/624 (12%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
PE+ S VC + W N + + S+ T
Sbjct 341 PEALSRTRASTARFVC-------RASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVIT 393
Query 93 DIASLNI-QLTCNILTFGQLE--QNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGG 149
I + C + + + GL P P ++ + W+
Sbjct 394 QIGLQDAGYYQCVAENSAGMACAAASLAVVVREGL-PSAPTRVTATPLSSSAVLVAWERP 452
Query 150 RETHLETN-FTLKSEWA-THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG-K 206
+ F+L + A + + + T+ + E +V A + LG
Sbjct 453 EMHSEQIIGFSLHYQKARGMDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGAS 512
Query 207 VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN--PSIKSVIILKYNIQYRTK 264
TS + V P + S S +++ W PS+ + ++KY I+Y
Sbjct 513 RTSTPALVHTLDDVPSAAPQ---LSLSSPNPSDIRVAWLPLPPSLSNGQVVKYKIEY--- 566
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
QI + + + L+P Y RI G G S W + +
Sbjct 567 GLGKEDQIFSTEVRGNETQLMLNSLQPNKVYRVRISAGTAAGFGAPSQWMHHRTPSMHNQ 626
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT--- 381
S P + + ++ + W+ P I Y++ + +
Sbjct 627 --SHVP--FAPAELKVQAKMESLVVSWQPPPHPTQ---ISGYKLYWREVGAEEEANGDRL 679
Query 382 -------------------VNATKLTVNLTNDRYLATLTVRNL---------VGKSDAAV 413
V +LT + Y L N GK++ A
Sbjct 680 PGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAP 739
Query 414 LTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITD 469
P + A +W+ W P + Y + + + +
Sbjct 740 APDMPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFSPWGLRNASLVT 799
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITV--TPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
+ G L G L Y V V DGP ++ L P + +R
Sbjct 800 YYTSSG---EDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRL 856
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY----RTIIGNETAVNVDSSHTEYTLSSLT 583
+ + L W P NG I Y I Y T + + + L
Sbjct 857 SPLTPSTVRLHW--CPPTEPNGEIVEYLILYSSNHTQPEHQWTLLTTQGNIFSAEVHGLE 914
Query 584 SDTLYMVRMAAYTDEGGKDGPEFT 607
SDT Y +M A T+ G
Sbjct 915 SDTRYFFKMGARTEVGPGPFSRLQ 938
>sp|P26992|CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit
alpha OS=Homo sapiens OX=9606 GN=CNTFR PE=1 SV=2
Length=372
Score = 158 bits (398), Expect = 7e-41, Method: Composition-based stats.
Identities = 63/294 (21%), Positives = 110/294 (37%), Gaps = 28/294 (10%)
Query 39 QLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLN 98
+L S+ T C + W+ N + ++N + + ++
Sbjct 37 RLGSDVTLPCGTANW--------DAAVTWRVNGTDLAP---DLLNGSQLVLHGLELGHSG 85
Query 99 IQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNE-GKKMRCEWDGGRETHLETN 157
+ + ++ Q + + GLPP +P LSC N K C W T++
Sbjct 86 LYACFHRDSWHLRHQ----VLLHVGLPPREPV-LSCRSNTYPKGFYCSWHLPTPTYIPNT 140
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDP 216
F + K C+ C + Y ++ + +V + NALG + I FD
Sbjct 141 FNVTVLH-GSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGH-NATAITFDE 198
Query 217 VYKVKPNPPHNLSVINSEELSSILKLTWTNPS---IKSVIILKYNIQYRTKDASTWSQIP 273
VKP+PP N+ L++TW PS LK+ ++YR W +
Sbjct 199 FTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVE 258
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
D ++ T+ D EY+ ++ ++ G WSDWS A + + P
Sbjct 259 LSD----GTAHTITDAYAGKEYIIQVAAK-DNEIGTWSDWSVAAHATPWTEEPR 307
Score = 38.3 bits (87), Expect = 0.29, Method: Composition-based stats.
Identities = 25/132 (19%), Positives = 51/132 (39%), Gaps = 12/132 (9%)
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN---MLWVEWTTPR--ES 449
+Y +++V N +G +A +T P ++ A P + L V W TP
Sbjct 176 KYKVSISVSNALGH-NATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPD 234
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD-GPGSPE 508
+ + L++ + + WQ + + + + K Y+I V + G S
Sbjct 235 PESFPLKFFLRYRPL-ILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDW 293
Query 509 SIKA----YLKQ 516
S+ A + ++
Sbjct 294 SVAAHATPWTEE 305
>sp|Q91513|PRLR_ORENI Prolactin receptor OS=Oreochromis niloticus
OX=8128 GN=prlr PE=2 SV=1
Length=630
Score = 163 bits (411), Expect = 1e-40, Method: Composition-based stats.
Identities = 54/209 (26%), Positives = 88/209 (42%), Gaps = 19/209 (9%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWAT----HKFADCKAKRDTPTS 181
P KP + C E + C W G + L T + L H+ D S
Sbjct 29 PGKPTEIKCRSPEKETFTCWWKPGSDGGLPTTYALYYRKEGSDVVHECPDY--HTAGKNS 86
Query 182 CTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV-INSEELSSI 239
C + + +V+ + V A NALGK SD + D VY V+P+PP L V + ++
Sbjct 87 CFFNKNNTLIWVSYNITVVATNALGKTYSDPQDIDVVYIVQPHPPEKLEVTVMKDQGWPF 146
Query 240 LKLTWTNPSIKSV----IILKYNIQYRTKDAST-WSQIPPEDTASTRSSFTVQDLKPFTE 294
L+++W P I L Y ++ + +D + W A + F + L+
Sbjct 147 LRVSWEPPRKADTRSGWITLIYELRVKLEDEESEWEN----HAAGQQKMFNIFSLRSGGT 202
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYE 323
Y+ ++RC + G+WS+WS + E
Sbjct 203 YLIQVRCKPD--HGFWSEWSSTSYVKVPE 229
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 37/193 (19%), Positives = 62/193 (32%), Gaps = 19/193 (10%)
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN-----YTVNATKLTVNLTN 393
+ T WK P G Y + + S + + +T N N
Sbjct 37 CRSPEKETFTCWWK---PGSDGGLPTTYALYYRKEGSDVVHECPDYHTAGKNSCFFNKNN 93
Query 394 D----RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW----VEWTT 445
Y T+ N +GK+ + I HP L+ + W V W
Sbjct 94 TLIWVSYNITVVATNALGKTYSDPQDIDVVYIVQPHPPEKLEVTVMKDQGWPFLRVSWEP 153
Query 446 PRES--VKKYI-LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD 502
PR++ +I L + + ++W+ + + +L YLI V
Sbjct 154 PRKADTRSGWITLIYELRVKLEDEESEWENHAAGQQKMFNIFSLRSGGTYLIQVRCKPDH 213
Query 503 GPGSPESIKAYLK 515
G S S +Y+K
Sbjct 214 GFWSEWSSTSYVK 226
>sp|Q71DR4|CNTFR_CANLF Ciliary neurotrophic factor receptor subunit
alpha OS=Canis lupus familiaris OX=9615 GN=CNTFR PE=2
SV=1
Length=372
Score = 157 bits (396), Expect = 1e-40, Method: Composition-based stats.
Identities = 63/294 (21%), Positives = 109/294 (37%), Gaps = 28/294 (10%)
Query 39 QLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLN 98
+L S+ T C + W+ N + ++N + + ++
Sbjct 37 RLGSDVTLPCGTANW--------DAAVTWRVNGTDLA---LDLLNGSQLVLHGLELGHSG 85
Query 99 IQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNE-GKKMRCEWDGGRETHLETN 157
+ + ++ Q + + GLPP +P LSC N K C W T++
Sbjct 86 LYACFHRDSWHLRHQ----VLLHVGLPPREPV-LSCRSNTYPKGFYCSWHLPTPTYIPNT 140
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDP 216
F + K C+ C + Y ++ + +V + NALG + I FD
Sbjct 141 FNVTVLH-GSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGH-NATAITFDE 198
Query 217 VYKVKPNPPHNLSVINSEELSSILKLTWTNPS---IKSVIILKYNIQYRTKDASTWSQIP 273
VKP+PP N+ L++TW PS LK+ ++YR W +
Sbjct 199 FTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVE 258
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
D ++ T+ D EY+ ++ + G WSDWS A + + P
Sbjct 259 LSD----GTTHTITDAYAGKEYIIQVAAK-DYEIGTWSDWSVAAHATPWTEEPR 307
Score = 39.1 bits (89), Expect = 0.18, Method: Composition-based stats.
Identities = 22/109 (20%), Positives = 43/109 (39%), Gaps = 7/109 (6%)
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN---MLWVEWTTPR--ES 449
+Y +++V N +G +A +T P ++ A P + L V W TP
Sbjct 176 KYKVSISVSNALGH-NATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPD 234
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
+ + L++ + + WQ + + T+ + K Y+I V
Sbjct 235 PESFPLKFFLRYRPL-ILDQWQHVELSDGTTHTITDAYAGKEYIIQVAA 282
>sp|P22273|IL6RA_RAT Interleukin-6 receptor subunit alpha OS=Rattus
norvegicus OX=10116 GN=Il6r PE=2 SV=2
Length=462
Score = 159 bits (402), Expect = 2e-40, Method: Composition-based stats.
Identities = 65/304 (21%), Positives = 114/304 (38%), Gaps = 37/304 (12%)
Query 41 HSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQ 100
+ T +C KE + I W + + T + T + ++ +
Sbjct 40 GATVTLICPGKEAAGNAT------IHWVYSGSQSRE-------WTTTGNTLV-LRAVQVN 85
Query 101 LTCNILTFGQLEQNVYG-ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFT 159
T + L F L+ ++ G + ++ +PPE+PK N CEW T
Sbjct 86 DTGHYLCF--LDDHLVGTVPLLVDVPPEEPKLSCFRKNPLVNAFCEWHPSSTPSPTTKAV 143
Query 160 LKSEWATHKFADCKAKRDTPTSCTVDYSTVYF-----------VNIEVWVEAENALGKVT 208
+ ++ K K D C F V V + N++G +
Sbjct 144 MFAK----KINTTNGKSDFQVPCQYSQQLKSFSCEVEILEGDKVYHIVSLCVANSVGSRS 199
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS--IKSVIILKYNIQYRTKDA 266
S ++ F + V+P+PP NL V LK++W +P S +L++ ++YR
Sbjct 200 SHNVVFQSLKMVQPDPPANLVVSAIPGXPRWLKVSWQDPESWDPSYYLLQFELRYRPV-W 258
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
S + P A + + D ++V ++R +E G WS WS E +G + P
Sbjct 259 SKXFTVWPLQVA--QHQCVIHDALRGVKHVVQVRGKEEFDIGQWSKWSPEVTGTPWLAEP 316
Query 327 SKAP 330
P
Sbjct 317 RTTP 320
>sp|Q2VWP9|PRTG_RAT Protogenin OS=Rattus norvegicus OX=10116 GN=Prtg
PE=2 SV=1
Length=1193
Score = 165 bits (418), Expect = 2e-40, Method: Composition-based stats.
Identities = 103/621 (17%), Positives = 195/621 (31%), Gaps = 64/621 (10%)
Query 20 STGELLDPCGYIS-PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQ 78
+T +L P ++ PES VC + + + W N I
Sbjct 314 ATLTVLAPPSFVEWPESLTRPRAGTARFVC-------QAEGIPSPKMSWLKNGRRIHSNG 366
Query 79 YTIINRTASSVTFTDIASLNIQLTCNILTF-GQLEQNVYGITIISGLPPEKPKNLSCIVN 137
+ + + I + C G + ++S P P N+
Sbjct 367 RIKMYNSKLVIN-QIIPEDDAIYQCMAENSQGSVLSRARLTVVMSEDRPSAPYNVHAETM 425
Query 138 EGKKMRCEWDGG-----RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV 192
+ W+ + ++ +K+E ++ DT D
Sbjct 426 SSSAILLAWERPLYNSDKVIAYSVHY-MKAEGLNNEEYQVVLGNDTTHYIIDDLEPD--S 482
Query 193 NIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW--TNPSI 249
N ++ A +G SDH+ + + V PP + + + + ++W
Sbjct 483 NYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPPE---ISLTSRSPTDILISWLPIPAKY 539
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ ++ Y + +R ++ + T + ++ L+P + Y+ RI G G
Sbjct 540 RRGQVVLYRLSFRLSTENSIQVVE---LPGTVHEYLLEGLEPDSVYLVRITAATRVGLGE 596
Query 310 WSDWSEEASGITYEDRPSKAP-SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
S W S T + KAP S ++P T+ + W L E I Y++
Sbjct 597 SSVW---TSHRTPKATSVKAPKSPELHLEP---LNCTTISVRW--LQDTEDPAAIRGYKL 648
Query 369 TLTRWKSHLQNYTVNAT-----KLTVNLTNDRYLATLTVRNLV--GKSDAAVLTIPACDF 421
T L+ +Y L N + G ++ P C
Sbjct 649 FYKEEGQQEHGPIFLDTGDLLYTLSGLDPRRKYHVRLLAYNNLEDGYQADQTVSTPGCVS 708
Query 422 QATHPVMDLKAFPK-------DNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQ 471
V + +++ W P V Y + + + + +
Sbjct 709 VRDRMVPPPPPPHHLYAKANTSSSIFLHWRRPAFTTAQVINYTIRCNPVGLQNASLVLYL 768
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYAD--GPGSPESIKAYLKQAPPSKGPTVRTKK 529
Q T L L + Y V P SP L +AP V+
Sbjct 769 Q---TSETHMLVQGLEPNTKYEFAVRLHVDQLSSPWSPVVYHTTLPEAPTGPPVGVKVTL 825
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT----IIGNETAVNVDSSHTEYTLSSLTSD 585
+ + A++ W P D + YTI Y + I G ++ + + T L +L +
Sbjct 826 IEDDTALVSWK--PPDGPETVVTRYTILYASRKAWIAGEWQVLHREGAITMALLENLVAG 883
Query 586 TLYMVRMAAYTDEGGKDGPEF 606
+Y+V+++A + G P
Sbjct 884 NVYIVKISASNEVGEGPFPNS 904
Score = 119 bits (297), Expect = 7e-26, Method: Composition-based stats.
Identities = 54/312 (17%), Positives = 104/312 (33%), Gaps = 37/312 (12%)
Query 319 GITYEDRPS--------KAPSFWYKIDPSHTQGYRTVQLVW-KTLPPFEANGKILDYEVT 369
+T PS P +G + ++ W K +NG+I Y
Sbjct 315 TLTVLAPPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRRIHSNGRIKMYN-- 372
Query 370 LTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDA-AVLTIPACDFQATHP 426
+KL +N + D + N G + A LT+ + + + P
Sbjct 373 ---------------SKLVINQIIPEDDAIYQCMAENSQGSVLSRARLTVVMSEDRPSAP 417
Query 427 VMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
+ + + W P + V Y + + + + ++Q G Y+
Sbjct 418 YNVHAETMSSSAILLAWERPLYNSDKVIAYSVHY--MKAEGLNNEEYQVVLGNDTTHYII 475
Query 484 GNLAESKCYLITVTPVYADG-PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
+L Y + G + + + P + P + + ++ W +
Sbjct 476 DDLEPDSNYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPPEISLTSRSPTDILISWLPI 535
Query 543 PVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
P + G + Y + +R N V + + EY L L D++Y+VR+ A T G
Sbjct 536 PAKYRRGQVVLYRLSFRLSTENSIQVVELPGTVHEYLLEGLEPDSVYLVRITAATRVGLG 595
Query 602 DGP-EFTFTTPK 612
+ + TPK
Sbjct 596 ESSVWTSHRTPK 607
Score = 106 bits (265), Expect = 4e-22, Method: Composition-based stats.
Identities = 61/312 (20%), Positives = 108/312 (35%), Gaps = 29/312 (9%)
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS- 375
+ + EDRPS + + T + L W+ P + K++ Y V + +
Sbjct 405 LTVVMSEDRPSAPYNVH-----AETMSSSAILLAWE--RPLYNSDKVIAYSVHYMKAEGL 457
Query 376 HLQNYTV----NATKLTVNLTN--DRYLATLTVRNLVGKSDAA--VLTIPACDFQATHPV 427
+ + Y V + T ++ Y + +G S + V D P
Sbjct 458 NNEEYQVVLGNDTTHYIIDDLEPDSNYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPPE 517
Query 428 MDLKAFPKDNMLWVEWTT-PRESVKKYILEWCVLSD-KAPCITDWQQEDGTVHRTYLRGN 485
+ L + + + W P + + ++ + + + GTVH YL
Sbjct 518 ISLTS-RSPTDILISWLPIPAKYRRGQVVLYRLSFRLSTENSIQVVELPGTVHE-YLLEG 575
Query 486 LAESKCYLITVTPVYADGPGSPESIKA-YLKQA----PPSKGPTVRTKKVGKNEAVLEWD 540
L YL+ +T G G + +A P P + + + + W
Sbjct 576 LEPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAPKS-PELHLEPLNCTTISVRWL 634
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
Q IR Y +FY+ E + +D+ YTLS L Y VR+ AY +
Sbjct 635 Q--DTEDPAAIRGYKLFYKEEGQQEHGPIFLDTGDLLYTLSGLDPRRKYHVRLLAYNNLE 692
Query 600 GKDGPEFTFTTP 611
+ T +TP
Sbjct 693 DGYQADQTVSTP 704
Score = 70.7 bits (171), Expect = 5e-11, Method: Composition-based stats.
Identities = 30/194 (15%), Positives = 66/194 (34%), Gaps = 5/194 (3%)
Query 136 VNEGKKMRCEWDGGRETHLET-NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNI 194
N + W T + N+T++ + A T + +
Sbjct 727 ANTSSSIFLHWRRPAFTTAQVINYTIRCNPVGLQNASLVLYLQTSETHMLVQGLEPNTKY 786
Query 195 EVWVEA-ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI 253
E V + L S + + + PP + V E+ ++++ +W P +
Sbjct 787 EFAVRLHVDQLSSPWSPVVYHTTLPEAPTGPPVGVKVTLIEDDTALV--SWKPPDGPETV 844
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ +Y I Y ++ A + + +++L Y+ +I E G+G +
Sbjct 845 VTRYTILYASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVKISASNEVGEGPF-PN 903
Query 314 SEEASGITYEDRPS 327
S E + + + S
Sbjct 904 SVELAVLPKDASES 917
>sp|Q589G5|PRTG_CHICK Protogenin OS=Gallus gallus OX=9031 GN=PRTG
PE=2 SV=1
Length=1187
Score = 164 bits (415), Expect = 4e-40, Method: Composition-based stats.
Identities = 106/617 (17%), Positives = 197/617 (32%), Gaps = 64/617 (10%)
Query 20 STGELLDPCGYIS-PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQ 78
+T +L P ++ PES C + A I W N I
Sbjct 311 ATLTVLAPPSFVEWPESLTRPRAGTARFAC-------QAEGIPAPKISWLKNGRRIHSNG 363
Query 79 YTIINRTASSVTFTDIASLNIQLTCNILTF-GQLEQNVYGITIISGLPPEKPKNLSCIVN 137
+ + + I + C G + ++S P P N+
Sbjct 364 RIKMYNSKLVIN-QIIPEDDAIYQCMAENSQGSVLSRARLTVVMSEDRPSAPYNVHAETM 422
Query 138 EGKKMRCEWDGG-----RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV 192
+ W+ + ++ +K+E ++ DT D
Sbjct 423 SSSAILLAWERPLYNSDKVIAYSVHY-MKAEGLNNEEYQVVIGNDTTHYIIDDLEPA--S 479
Query 193 NIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW--TNPSI 249
N ++ A LG SDH+ + V P + + + + ++W
Sbjct 480 NYTFYIVAYMPLGASQMSDHVTQHTLEDVPLRAPE---ISLTSRSPTDILISWLPIPAKY 536
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ ++ Y + +R ST S+I + T + ++ L+P + Y+ RI G
Sbjct 537 RRGQVVLYRLSFRL---STDSKIQVLELPGTSDEYLLEGLRPDSVYLVRITAATRIG--- 590
Query 310 WSDWSEEASGITYEDRPSKAP-SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
W + S S T + KAP S +++P T+ + W+ A I Y++
Sbjct 591 WGEASLWTSHRTPKATSVKAPKSPELRLEP---INCTTITVQWQQDSDDTA--AIQGYKL 645
Query 369 TLTRWKSHLQ-NYTVNATKLTVNL----TNDRYLATLTVRNLV--GKSDAAVLTIPACDF 421
++A+ L + +Y L N + G ++ P C
Sbjct 646 YYKEEGQQENGPILLDASDLEYTVSGLDPRRKYHVRLLAYNNMEEGYQADQTVSTPGCVS 705
Query 422 QATHPVMDLKAFPK-------DNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQ 471
V + +++ W P V Y + + + + +
Sbjct 706 VRDRMVPPPPPPHHLYAKANTSSSIYLHWGKPAFTSAQVINYTIRCNPVGLQNASLVLYL 765
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYAD--GPGSPESIKAYLKQAPPSKGPTVRTKK 529
Q T L L Y V P SP L +AP V+
Sbjct 766 Q---TSETHMLVQGLEPKTMYEFAVRLHVDQLSSPWSPVVYHTTLPEAPSGPPVGVKVTL 822
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT----IIGNETAVNVDSSHTEYTLSSLTSD 585
+ + A++ W P D + YTI Y + I G ++ + + T L +L +
Sbjct 823 IEDDTALVSWK--PPDGPETVVTRYTILYASRKSWIAGEWQVLHREGAMTMALLENLVAG 880
Query 586 TLYMVRMAAYTDEGGKD 602
+Y+V++AA + G
Sbjct 881 NVYLVKIAASNEVGEGP 897
Score = 112 bits (279), Expect = 9e-24, Method: Composition-based stats.
Identities = 57/311 (18%), Positives = 106/311 (34%), Gaps = 27/311 (9%)
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
+ + EDRPS + + T + L W+ P + K++ Y V + +
Sbjct 402 LTVVMSEDRPSAPYNVH-----AETMSSSAILLAWE--RPLYNSDKVIAYSVHYMKAEGL 454
Query 377 LQN-----YTVNATKLTVNLTNDR--YLATLTVRNLVGKSDAA--VLTIPACDFQATHPV 427
+ T ++ Y + +G S + V D P
Sbjct 455 NNEEYQVVIGNDTTHYIIDDLEPASNYTFYIVAYMPLGASQMSDHVTQHTLEDVPLRAPE 514
Query 428 MDLKAFPKDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
+ L + + + W P + + ++ + + + E YL L
Sbjct 515 ISLTS-RSPTDILISWLPIPAKYRRGQVVLYRLSFRLSTDSKIQVLELPGTSDEYLLEGL 573
Query 487 AESKCYLITVTPVYADGPGSPESIKA-YLKQA----PPSKGPTVRTKKVGKNEAVLEWDQ 541
YL+ +T G G + +A P P +R + + ++W Q
Sbjct 574 RPDSVYLVRITAATRIGWGEASLWTSHRTPKATSVKAPKS-PELRLEPINCTTITVQWQQ 632
Query 542 LPVDVQNGFIRNYTIFYRTIIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
D I+ Y ++Y+ E + +D+S EYT+S L Y VR+ AY +
Sbjct 633 DSDDTAA--IQGYKLYYKEEGQQENGPILLDASDLEYTVSGLDPRRKYHVRLLAYNNMEE 690
Query 601 KDGPEFTFTTP 611
+ T +TP
Sbjct 691 GYQADQTVSTP 701
Score = 112 bits (279), Expect = 9e-24, Method: Composition-based stats.
Identities = 52/312 (17%), Positives = 105/312 (34%), Gaps = 37/312 (12%)
Query 319 GITYEDRPS--------KAPSFWYKIDPSHTQGYRTVQLVW-KTLPPFEANGKILDYEVT 369
+T PS P +G ++ W K +NG+I Y
Sbjct 312 TLTVLAPPSFVEWPESLTRPRAGTARFACQAEGIPAPKISWLKNGRRIHSNGRIKMYN-- 369
Query 370 LTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDA-AVLTIPACDFQATHP 426
+KL +N + D + N G + A LT+ + + + P
Sbjct 370 ---------------SKLVINQIIPEDDAIYQCMAENSQGSVLSRARLTVVMSEDRPSAP 414
Query 427 VMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
+ + + W P + V Y + + + + ++Q G Y+
Sbjct 415 YNVHAETMSSSAILLAWERPLYNSDKVIAYSVHY--MKAEGLNNEEYQVVIGNDTTHYII 472
Query 484 GNLAESKCYLITVTPVYADG-PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
+L + Y + G + + + + P + P + + ++ W +
Sbjct 473 DDLEPASNYTFYIVAYMPLGASQMSDHVTQHTLEDVPLRAPEISLTSRSPTDILISWLPI 532
Query 543 PVDVQNGFIRNYTIFYR-TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
P + G + Y + +R + + + + EY L L D++Y+VR+ A T G
Sbjct 533 PAKYRRGQVVLYRLSFRLSTDSKIQVLELPGTSDEYLLEGLRPDSVYLVRITAATRIGWG 592
Query 602 DGP-EFTFTTPK 612
+ + TPK
Sbjct 593 EASLWTSHRTPK 604
Score = 92.6 bits (228), Expect = 9e-18, Method: Composition-based stats.
Identities = 53/315 (17%), Positives = 93/315 (30%), Gaps = 28/315 (9%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P+ P+ L + +W +T + L + + + D
Sbjct 611 PKSPE-LRLEPINCTTITVQWQQDSDDTAAIQGYKLYYKEEGQQ-ENGPILLDASDLEYT 668
Query 185 DYSTVYFVNIEVWVEAENAL------GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
V + A N + + S ++ P PP + SS
Sbjct 669 VSGLDPRRKYHVRLLAYNNMEEGYQADQTVSTPGCVSVRDRMVPPPPPPHHLYAKANTSS 728
Query 239 ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ L W P+ S ++ Y I+ S + T + + VQ L+P T Y F
Sbjct 729 SIYLHWGKPAFTSAQVINYTIRCNPVGLQNASLVLYLQT--SETHMLVQGLEPKTMYEFA 786
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+R + S WS T + PS P T + WK E
Sbjct 787 VRLHVDQ---LSSPWSPVVYHTTLPEAPSGPP----VGVKVTLIEDDTALVSWKPPDGPE 839
Query 359 ANGKILDYEVTL--------TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD 410
+ Y + W+ + + L + + YL + N VG+
Sbjct 840 TV--VTRYTILYASRKSWIAGEWQVLHREGAMTMALLENLVAGNVYLVKIAASNEVGEGP 897
Query 411 AAVLTIPACDFQATH 425
+ + A + T
Sbjct 898 FSNVVELAVLPKETS 912
>sp|P22272|IL6RA_MOUSE Interleukin-6 receptor subunit alpha OS=Mus
musculus OX=10090 GN=Il6ra PE=1 SV=2
Length=460
Score = 158 bits (398), Expect = 5e-40, Method: Composition-based stats.
Identities = 64/305 (21%), Positives = 110/305 (36%), Gaps = 39/305 (13%)
Query 41 HSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQ 100
+ T +C KE + I W + ++T T + + +
Sbjct 40 GATVTLICPGKEAAGNVT------IHWVYSGS--QNREWTTTGNTLV------LRDVQLS 85
Query 101 LTCNILTFGQLEQNVYG-ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFT 159
T + L L ++ G + ++ +PPE+PK N CEW T
Sbjct 86 DTGDYLCS--LNDHLVGTVPLLVDVPPEEPKLSCFRKNPLVNAICEWRPSSTPSPTTKAV 143
Query 160 LKSEWATHKFADCKAKRDTPTSCTVDYSTVYF-----------VNIEVWVEAENALGKVT 208
L ++ K K D C F V V + N++G +
Sbjct 144 LFAK----KINTTNGKSDFQVPCQYSQQLKSFSCQVEILEGDKVYHIVSLCVANSVGSKS 199
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS--IKSVIILKYNIQYRTKDA 266
S + F + V+P+PP NL V LK++W +P S +L++ ++YR
Sbjct 200 SHNEAFHSLKMVQPDPPANLVVSAIPGRPRWLKVSWQHPETWDPSYYLLQFQLRYRP--- 256
Query 267 STWS-QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
WS + + + D ++V ++R +E G WS+WS E +G +
Sbjct 257 -VWSKEFTVLLLPVAQYQCVIHDALRGVKHVVQVRGKEELDLGQWSEWSPEVTGTPWIAE 315
Query 326 PSKAP 330
P P
Sbjct 316 PRTTP 320
>sp|Q3KNY0|IGFN1_MOUSE Immunoglobulin-like and fibronectin type
III domain-containing protein 1 OS=Mus musculus OX=10090 GN=Igfn1
PE=1 SV=3
Length=2849
Score = 164 bits (415), Expect = 7e-40, Method: Composition-based stats.
Identities = 91/495 (18%), Positives = 165/495 (33%), Gaps = 39/495 (8%)
Query 125 PPEKPKNLS-CIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTS 181
PP+ P + C + W R+ + ++ ++ A + + ++
Sbjct 2244 PPQGPLEVQDCHRA---GVCLRWLPPRDNGGQVIQHYVVERRQAGRSTWLKVGEPPSDST 2300
Query 182 CTVDYSTVYFVNIEVWVEAENALGK---VTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
D S V A ++G + S+ + P P PP +++++ S
Sbjct 2301 SFTDTSVEQGKKYAFRVRAVTSVGAGDALESEEVLVAPEAL--PGPPSAPAILSA--SSQ 2356
Query 239 ILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ LTW P IL Y I+ K ++TW + + + +TV L+ +Y F
Sbjct 2357 SITLTWGAPQGPGSNHILGYLIEKHKKGSNTWMAVNEQPV--SERRYTVVGLRQGCQYEF 2414
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
R+ + G G S+ P + P + + T ++ + W +P
Sbjct 2415 RVTAVTLSGPGDPGPPSDAVFARD----PMRPPGPVRDLQVTDTS-NTSITVSWM-VPDA 2468
Query 358 EANGKILDYEVTLTRWKSHLQN----YTVNATKLTVNLTNDR--YLATLTVRNLVGKSDA 411
+ Y V L SH + TV T T + Y +T N G+S A
Sbjct 2469 RDADEAQGYIVELCGSDSHQWSPCHVGTVPGTTFTAKGLRPQEGYFVRVTAVNDGGRSQA 2528
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWV----EWTTPR--ESVKKYILEWCVLSDKAP 465
L AT L + L V P E+ + W P
Sbjct 2529 TSLDTLVHAMPATVCPRFLMDSGTKDTLMVRVGDSIRVPLSFEAAPMPEVTWLKDGLPLP 2588
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
+ + G +L++ Y TV G + S + A P ++
Sbjct 2589 KRSVTTVKAGLTQLLIPAASLSDCGRY--TVMLRNLQGKEATHSFFINVA-ACPQAPGSI 2645
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAVNVDSSHTEYTLSSLTS 584
++ ++W+ P + Q G +YT+ R+ + V +TL +
Sbjct 2646 YLQENVPGTVTVQWEPSPDEAQ-GIPLHYTVLMRSSSHRSWHEVADHVRTNRFTLLGVLP 2704
Query 585 DTLYMVRMAAYTDEG 599
Y R+ A + G
Sbjct 2705 GHEYHFRVLAKNELG 2719
Score = 116 bits (290), Expect = 5e-25, Method: Composition-based stats.
Identities = 59/300 (20%), Positives = 90/300 (30%), Gaps = 25/300 (8%)
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK-ILDYEV----TLTRWKSHLQ 378
D+P P ++ H G V L W LPP + G+ I Y V +
Sbjct 2240 DKPQ-PPQGPLEVQDCHRAG---VCLRW--LPPRDNGGQVIQHYVVERRQAGRSTWLKVG 2293
Query 379 NYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF--P 434
++T T +Y + VG DA +A A
Sbjct 2294 EPPSDSTSFTDTSVEQGKKYAFRVRAVTSVGAGDALESEEVLVAPEALPGPPSAPAILSA 2353
Query 435 KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ--QEDGTVHRTYLRGNLAESKCY 492
+ + W P+ +IL + + K T W E R Y L + Y
Sbjct 2354 SSQSITLTWGAPQGPGSNHILGYLIEKHKKGSNT-WMAVNEQPVSERRYTVVGLRQGCQY 2412
Query 493 LITVTPVYADGPGSPES----IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
VT V GPG P + A PP ++ + W +P
Sbjct 2413 EFRVTAVTLSGPGDPGPPSDAVFARDPMRPPGPVRDLQVTDTSNTSITVSW-MVPDARDA 2471
Query 549 GFIRNYTIFYRTIIGN-ETAVNVDS-SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
+ Y + + + +V + T +T L Y VR+ A D G
Sbjct 2472 DEAQGYIVELCGSDSHQWSPCHVGTVPGTTFTAKGLRPQEGYFVRVTAVNDGGRSQATSL 2531
Score = 105 bits (262), Expect = 1e-21, Method: Composition-based stats.
Identities = 57/307 (19%), Positives = 102/307 (33%), Gaps = 22/307 (7%)
Query 311 SDWSEEASGITYEDRPSKAPSF---WYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
S+ S +T +D P+ AP + TV++ +++ P +A + E
Sbjct 2132 SEAS-----LTVQDPPTIAPDVTETLREPLVFKAGKPVTVKIPFQSRLPVQAAWRKDGNE 2186
Query 368 VTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATH 425
V K T L + D ++T+R+ G A Q
Sbjct 2187 VVGGDHKGIQLALADGYTWLCLPSVCRKDSGRYSVTLRSEGGCVQAEFTLQVIDKPQPPQ 2246
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQ--EDGTVHRTYLR 483
++++ + + + W PR++ + I + V+ + + W + E + ++
Sbjct 2247 GPLEVQDCHRA-GVCLRWLPPRDNGGQVIQHY-VVERRQAGRSTWLKVGEPPSDSTSFTD 2304
Query 484 GNLAESKCYLITVTPVY--ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
++ + K Y V V G +A P L W
Sbjct 2305 TSVEQGKKYAFRVRAVTSVGAGDALESEEVLVAPEALPGPPSAPAILSASSQSITLTWGA 2364
Query 542 LPVDVQNGFIRNYTIFYRTIIGNETAVNVDS---SHTEYTLSSLTSDTLYMVRMAAYTDE 598
N I Y I + G+ T + V+ S YT+ L Y R+ A T
Sbjct 2365 PQGPGSN-HILGYLIE-KHKKGSNTWMAVNEQPVSERRYTVVGLRQGCQYEFRVTAVTLS 2422
Query 599 G-GKDGP 604
G G GP
Sbjct 2423 GPGDPGP 2429
Score = 103 bits (256), Expect = 6e-21, Method: Composition-based stats.
Identities = 68/429 (16%), Positives = 120/429 (28%), Gaps = 35/429 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD----GGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
PP P LS + + W G L + ++ ++
Sbjct 2344 PPSAPAILSA---SSQSITLTWGAPQGPGSNHIL--GYLIEKHKKGSNTWMAVNEQPVSE 2398
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS-VINSEELSSI 239
E V A G + + PP + + ++ ++
Sbjct 2399 RRYTVVGLRQGCQYEFRVTAVTLSGPGDPGPPSDAVFARDPMRPPGPVRDLQVTDTSNTS 2458
Query 240 LKLTWTNPSIKS-VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ ++W P + Y ++ D+ WS P ++FT + L+P Y R
Sbjct 2459 ITVSWMVPDARDADEAQGYIVELCGSDSHQWS--PCHVGTVPGTTFTAKGLRPQEGYFVR 2516
Query 299 IRCMKEDGKGYWSDWSEEASGITYE-DRPSKA-PSFWYKIDPSHTQGYRT-----VQLVW 351
+ + + G+ S+ S T P+ P F T R V L +
Sbjct 2517 VTAVNDGGR------SQATSLDTLVHAMPATVCPRFLMDSGTKDTLMVRVGDSIRVPLSF 2570
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA 411
+ P E + L + + + +D T+ +RNL GK
Sbjct 2571 EAAPMPEVTWLKDG--LPLPKRSVTTVKAGLTQLLIPAASLSDCGRYTVMLRNLQGKEAT 2628
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
I + L+ + V+W + + L + VL W
Sbjct 2629 HSFFINVAACPQAPGSIYLQENVPGT-VTVQWEPSPDEAQGIPLHYTVLMRS-SSHRSWH 2686
Query 472 QEDGTV--HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKK 529
+ V +R L G L Y V G P P + K
Sbjct 2687 EVADHVRTNRFTLLGVL-PGHEYHFRVLAKNELGVSKPS--DTSQPWCIPRQRDRFTVKS 2743
Query 530 VGKNEAVLE 538
+ L
Sbjct 2744 PTYQDPDLS 2752
Score = 57.2 bits (136), Expect = 8e-07, Method: Composition-based stats.
Identities = 31/139 (22%), Positives = 48/139 (35%), Gaps = 8/139 (6%)
Query 493 LITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
+VT G E + + P +GP + + + L W P D I+
Sbjct 2218 RYSVTLRSEGGCVQAEFTLQVIDKPQPPQGP-LEVQDCHRAGVCLRWLP-PRDNGGQVIQ 2275
Query 553 NYTIFYRTIIGNETAVNV---DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG--PEFT 607
+Y + R G T + V S T +T +S+ Y R+ A T G D E
Sbjct 2276 HYVVERRQA-GRSTWLKVGEPPSDSTSFTDTSVEQGKKYAFRVRAVTSVGAGDALESEEV 2334
Query 608 FTTPKFAQGEIEAIVVPVC 626
P+ G A +
Sbjct 2335 LVAPEALPGPPSAPAILSA 2353
>sp|Q28902|COCA1_RABIT Collagen alpha-1(XII) chain (Fragment)
OS=Oryctolagus cuniculus OX=9986 GN=COL12A1 PE=2 SV=1
Length=639
Score = 160 bits (405), Expect = 8e-40, Method: Composition-based stats.
Identities = 80/487 (16%), Positives = 151/487 (31%), Gaps = 57/487 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
E P NL + R W ++ + + KR ++
Sbjct 129 EAPSNLVISERTHRSFRVSWTPPSDSV--------DRYKVEYYPVSGGKRQEFYVSRLET 180
Query 187 STVYF-----VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
STV V V V D + K P +S+ + + ++
Sbjct 181 STVLKDLKPETEYVVNVY------SVVEDEYSEPLKGTEKTLPVPIVSLNIYDIGPTTMR 234
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+ W + Y + Y + ++ T + + DL P TEY ++
Sbjct 235 VQWQPVGGATG----YTVSYEPVKTTESTKPKEMRVGPTVNDVQLTDLLPSTEYEVTVQA 290
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ D SE A+ P P D +H+ T+ + W+ + G
Sbjct 291 VLHDLT------SEPATAREM-TLPLPRPQDVKLRDVTHS----TMSVFWEPV-----LG 334
Query 362 KILDYEVTLTRWKSHLQNY----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
K+ Y V + ++ + +T L L+ Y +++ G+S
Sbjct 335 KVRKYVVRYQTPEEDVKEVEVDRSRTSTSLKDLLSQTLYTVSVSAVYDEGESPPVTAQET 394
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
A + + P+ W V Y + W +
Sbjct 395 TRPVPAPTNLRITEVTPES--FRGTWDHGASDVSLYRITWAPFGSSD----KMETILNGD 448
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVL 537
T + NL + Y ++VT +Y D + + + +P S ++ N +
Sbjct 449 ENTLVFENLNPNTLYEVSVTAIYPD-ESESDDLTGSERTSPKSGPRNLQVYNATSNSLTV 507
Query 538 EWDQLPVDVQNGFIRNYTIFYRT--IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
+WD +G ++ Y I Y+ GNE + L L DT Y + +++
Sbjct 508 KWDP-----ASGRVQKYRITYQPSRGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSL 562
Query 596 TDEGGKD 602
+G
Sbjct 563 YPDGEGG 569
Score = 130 bits (327), Expect = 5e-30, Method: Composition-based stats.
Identities = 89/517 (17%), Positives = 168/517 (32%), Gaps = 56/517 (11%)
Query 76 KEQYTIINRTASSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSC 134
K Q ++R +S D+ + + + + + G +P +S
Sbjct 169 KRQEFYVSRLETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVP-----IVSL 223
Query 135 IVNE--GKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF 191
+ + MR +W G T ++ + T + + + +
Sbjct 224 NIYDIGPTTMRVQWQPVGGATGYTVSY--EPVKTTESTKPKEMRVGPTVNDVQLTDLLPS 281
Query 192 VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS 251
EV V+A L +TS+ + P P V + S + + W
Sbjct 282 TEYEVTVQAV--LHDLTSEPATAREMTLPLPRP---QDVKLRDVTHSTMSVFWEP---VL 333
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+ KY ++Y+T + + + +R+S +++DL T Y + + ++G+
Sbjct 334 GKVRKYVVRYQTPE----EDVKEVEVDRSRTSTSLKDLLSQTLYTVSVSAVYDEGE---- 385
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
S + RP AP+ + + T W + Y +T
Sbjct 386 --SPPVTAQ-ETTRPVPAPTNLRITEVTPESFRGT----WD-----HGASDVSLYRITWA 433
Query 372 RWKS-----HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
+ S + N N N Y ++T +S++ LT + P
Sbjct 434 PFGSSDKMETILNGDENTLVFENLNPNTLYEVSVTAI-YPDESESDDLTGSERTSPKSGP 492
Query 427 VMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
N L V+W V+KY + + + T G + + L
Sbjct 493 RNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSRGEGNEQT---TTIGGRQNSVVLQKL 549
Query 487 AESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDV 546
Y ITV+ +Y DG G + + K + +R + + WD
Sbjct 550 KPDTPYTITVSSLYPDGEGGRMTGRGKTKPL--NTVRNLRVYDPSTSTLNVRWDH----- 602
Query 547 QNGFIRNYTIFY-RTIIGNETAVNVDSSHTEYTLSSL 582
G R Y +FY T G+E V + + L +L
Sbjct 603 AEGNPRQYKLFYAPTAGGSEELVPIPGNTNYAILRNL 639
Score = 102 bits (254), Expect = 4e-21, Method: Composition-based stats.
Identities = 53/283 (19%), Positives = 98/283 (35%), Gaps = 15/283 (5%)
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT 399
+ +R+ ++ W K+ Y V+ + + + +T L Y+
Sbjct 137 SERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLETSTVLKDLKPETEYVVN 196
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWC 458
+ D + + P++ L + + V+W + Y + +
Sbjct 197 VYSVV----EDEYSEPLKGTEKTLPVPIVSLNIYDIGPTTMRVQWQPVGGAT-GYTVSYE 251
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ + TV+ L +L S Y +TV V D P + + P
Sbjct 252 PVKTTESTKPKEMRVGPTVNDVQL-TDLLPSTEYEVTVQAVLHDLTSEPATAREMTLPLP 310
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
+ V+ + V + + W+ + G +R Y + Y+T + V VD S T +
Sbjct 311 --RPQDVKLRDVTHSTMSVFWEPV-----LGKVRKYVVRYQTPEEDVKEVEVDRSRTSTS 363
Query 579 LSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEA 620
L L S TLY V ++A DEG T P A +
Sbjct 364 LKDLLSQTLYTVSVSAVYDEGESPPVTAQETTRPVPAPTNLRI 406
>sp|O88507|CNTFR_MOUSE Ciliary neurotrophic factor receptor subunit
alpha OS=Mus musculus OX=10090 GN=Cntfr PE=1 SV=2
Length=372
Score = 154 bits (389), Expect = 1e-39, Method: Composition-based stats.
Identities = 59/240 (25%), Positives = 98/240 (41%), Gaps = 14/240 (6%)
Query 94 IASLNIQLTCNILTFGQLEQNV-YGITIISGLPPEKPKNLSCIVNE-GKKMRCEWDGGRE 151
+ SL + + F + ++ + + + GLPP +P LSC N K C W
Sbjct 76 LRSLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPV-LSCRSNTYPKGFYCSWHLPTP 134
Query 152 THLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY-FVNIEVWVEAENALGKVTSD 210
T++ F + K C+ C + Y ++ + +V + NALG T+
Sbjct 135 TYIPNTFNVTVLH-GSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGHNTT- 192
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS---IKSVIILKYNIQYRTKDAS 267
I FD VKP+PP N+ L++TW PS LK+ ++YR
Sbjct 193 AITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILD 252
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
W + D ++ T+ D EY+ ++ ++ G WSDWS A + + P
Sbjct 253 QWQHVELSD----GTAHTITDAYAGKEYIIQVAAK-DNEIGTWSDWSVAAHATPWTEEPR 307
Score = 37.1 bits (84), Expect = 0.64, Method: Composition-based stats.
Identities = 24/132 (18%), Positives = 50/132 (38%), Gaps = 12/132 (9%)
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN---MLWVEWTTPR--ES 449
+Y +++V N +G + +T P ++ A P + L V W TP
Sbjct 176 KYKVSISVSNALGHNT-TAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPD 234
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD-GPGSPE 508
+ + L++ + + WQ + + + + K Y+I V + G S
Sbjct 235 PESFPLKFFLRYRPL-ILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDW 293
Query 509 SIKA----YLKQ 516
S+ A + ++
Sbjct 294 SVAAHATPWTEE 305
>sp|Q08406|CNTFR_RAT Ciliary neurotrophic factor receptor subunit
alpha OS=Rattus norvegicus OX=10116 GN=Cntfr PE=2 SV=2
Length=372
Score = 153 bits (386), Expect = 3e-39, Method: Composition-based stats.
Identities = 59/240 (25%), Positives = 98/240 (41%), Gaps = 14/240 (6%)
Query 94 IASLNIQLTCNILTFGQLEQNV-YGITIISGLPPEKPKNLSCIVNE-GKKMRCEWDGGRE 151
+ SL + + F + ++ + + + GLPP +P LSC N K C W
Sbjct 76 LRSLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPV-LSCRSNTYPKGFYCSWHLSAP 134
Query 152 THLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY-FVNIEVWVEAENALGKVTSD 210
T++ F + K C+ C + Y ++ + +V + NALG T+
Sbjct 135 TYIPNTFNVTVLH-GSKMMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGHNTT- 192
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS---IKSVIILKYNIQYRTKDAS 267
I FD VKP+PP N+ L++TW PS LK+ ++YR
Sbjct 193 AITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILD 252
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
W + S ++ T+ D EY+ ++ ++ G WSDWS A + + P
Sbjct 253 QWQHVEL----SNGTAHTITDAYAGKEYIIQVAAK-DNEIGTWSDWSVAAHATPWTEEPR 307
Score = 37.9 bits (86), Expect = 0.37, Method: Composition-based stats.
Identities = 24/132 (18%), Positives = 50/132 (38%), Gaps = 12/132 (9%)
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN---MLWVEWTTPR--ES 449
+Y +++V N +G + +T P ++ A P + L V W TP
Sbjct 176 KYKVSISVSNALGHNT-TAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPD 234
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD-GPGSPE 508
+ + L++ + + WQ + + + + K Y+I V + G S
Sbjct 235 PESFPLKFFLRYRPL-ILDQWQHVELSNGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDW 293
Query 509 SIKA----YLKQ 516
S+ A + ++
Sbjct 294 SVAAHATPWTEE 305
>sp|Q5RF19|I11RA_PONAB Interleukin-11 receptor subunit alpha OS=Pongo
abelii OX=9601 GN=IL11RA PE=2 SV=1
Length=422
Score = 153 bits (385), Expect = 1e-38, Method: Composition-based stats.
Identities = 51/233 (22%), Positives = 85/233 (36%), Gaps = 21/233 (9%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD 177
+T+ G PP +P +SC + + C W + + L T + T AD + +
Sbjct 105 VTLQLGYPPARPV-VSCQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSP 163
Query 178 --TPTSCTVD---------YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH 226
P C D + ++ + V N LG T ++ ++P+PP
Sbjct 164 STGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGASTR-LLDVSLQSILRPDPPQ 222
Query 227 NLSVINSEELSSILKLTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
L V + L+ +WT P+ + +LK+ +QYR WS + P
Sbjct 223 GLRVESVPGYPRRLRASWTYPASWPRQPHFLLKFRLQYRPAQHPAWSTVEPAGLEE---- 278
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ D + R+ G WS WS EA G K W ++
Sbjct 279 -VITDAVAGLPHAVRVSARDFLDAGTWSTWSPEAWGTPSTGTVPKEIPAWGQL 330
>sp|Q8BX90|FND3A_MOUSE Fibronectin type-III domain-containing
protein 3A OS=Mus musculus OX=10090 GN=Fndc3a PE=1 SV=3
Length=1198
Score = 159 bits (401), Expect = 2e-38, Method: Composition-based stats.
Identities = 89/487 (18%), Positives = 154/487 (32%), Gaps = 39/487 (8%)
Query 141 KMRCEWDGGRE-THLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV------- 192
+ W + E N T E ++ ++
Sbjct 281 TVLLTWSPPSSFINGEVNETAVPELFNYEVLVSSTGKEGKYRSVYIGEETSVTLNDLKPA 340
Query 193 -NIEVWVEAE-NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+ V+AE N++ + S+ +F + +P+PP+ + + + L L W PS
Sbjct 341 TDYHAKVQAESNSIKGIPSEAESFTTLSC-EPDPPNAPRI--ANRTKNSLTLQWKAPSDN 397
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
I + +++ D + + ++ F + L P FR+ + G
Sbjct 398 GSKIQSFILEW---DEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSAKNDYGV--- 451
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILDYEVT 369
SD+SEE T PS P T+ T + L W + + + Y +
Sbjct 452 SDFSEEVLYYTSGCAPSVP------ASPVLTKAGVTWLSLQWTKPSGT-PSDEGISYILE 504
Query 370 LTRWKSH---LQNYTVNATKLTV--NLTNDRYLATLTVRNLVGKS-DAAVLTIPACDFQA 423
+ S Y TV + +Y + N GKS + V+ C +
Sbjct 505 MEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFSTCPDKP 564
Query 424 THPVM-DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
PV +K + + W P+++ I ++ V + W R +L
Sbjct 565 GVPVKPSVKGKIHSHGFKITWDPPKDNGGAPINKYVVEMAEGSNGNKWDMIYSGTTREHL 624
Query 483 RGNLAESKCYLITVTPVYADGP-GSPESIKAYLKQAPPSK--GPTVRTKKVGKNEAVLEW 539
L Y + V + G ES+ PP P ++ + E L W
Sbjct 625 CDRLTPGCYYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQG-RPKAKEIQLRW 683
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
VD I Y + +E S E T+ SL Y R+ A G
Sbjct 684 GPPQVD-GGSPISCYAVEMTPADKDEPRDVYQGSEVECTVGSLLPGKTYSFRLRAANRIG 742
Query 600 GKDGPEF 606
E
Sbjct 743 FGPFSEK 749
Score = 152 bits (384), Expect = 2e-36, Method: Composition-based stats.
Identities = 79/500 (16%), Positives = 148/500 (30%), Gaps = 49/500 (10%)
Query 145 EWDGGRE--THLETNFTLKSEWA--THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
WD ++ + ++ +K+ + C Y + V
Sbjct 584 TWDPPKDNGGAPINKYVVEMAEGSNGNKWDMIYSGTTREHLCDRLTPGCY---YRLRVYC 640
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNI 259
+ G+ V P P + + ++L W P I Y +
Sbjct 641 ISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAK-EIQLRWGPPQVDGGSPISCYAV 699
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ D + + TV L P Y FR+R G G +S E
Sbjct 700 EMTPADKDEPRDVYQ----GSEVECTVGSLLPGKTYSFRLRAANRIGFGPFS----EKYD 751
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG-KILDYEVTLTRWKSHLQ 378
IT + P + + Q+ W+ +NG + +Y + + +Q
Sbjct 752 ITT----APGPPDQCRPPQVTCRSATCAQVNWE---IPLSNGTDVTEYRLEWGGVEGSMQ 804
Query 379 N---YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA--- 432
+ +L Y + ++VG + + V L+
Sbjct 805 MCYCGPGLSCELKGLSPATTYYCRVQAMSVVGAGPFSEVVACVTPPSVPAIVTCLQEISD 864
Query 433 -------FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+ L + W P + + IL + + + D Q +Y+ +
Sbjct 865 DDIEYPHYSPSTCLAISWKEPYDHGSE-ILAYSID------LGDKQPLTVGKMTSYIIDS 917
Query 486 LAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
L Y I + + + G G +IK K PP P + L+W +
Sbjct 918 LQPDTTYRIRIQALNSLGAGPFSHTIKLKTKPLPPD-PPRLECVAFNHQNLKLKWGEGTP 976
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD-G 603
+ Y + G ++ Y + L+ T Y + A + G
Sbjct 977 KTLSTDAVQYHLQMEDRNGRFVSL-YRGPCHTYKVQRLSESTSYKFCIQACNEAGEGPLS 1035
Query 604 PEFTFTTPKFAQGEIEAIVV 623
E+ FTTPK ++A +
Sbjct 1036 QEYVFTTPKSLPAALKAPKI 1055
Score = 121 bits (303), Expect = 1e-26, Method: Composition-based stats.
Identities = 73/409 (18%), Positives = 137/409 (33%), Gaps = 35/409 (9%)
Query 228 LSVINSEELSSILKLTWTNPSIK-SVII--------LKYNIQYRTKDASTWSQIPPEDTA 278
+ + S+ + + LTW+ PS + + Y + ++
Sbjct 270 VKPVASDIQARTVLLTWSPPSSFINGEVNETAVPELFNYEV---LVSSTGKEGKYRSVYI 326
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+S T+ DLKP T+Y +++ KG SE S T P P+ +
Sbjct 327 GEETSVTLNDLKPATDYHAKVQAESNSIKGI---PSEAESFTTLSCEPD-PPNAPRIANR 382
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ-----NYTVNATKLTVNLTN 393
+ ++ L WK P + KI + + K + + + K+T
Sbjct 383 TKN----SLTLQWKA--PSDNGSKIQSFILEWDEGKGNGEFCQCYMGSQKQFKITKLSPA 436
Query 394 DRYLATLTVRNLVGKSDAAVLTIPACDF-QATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
L+ +N G SD + + + P + L ++WT P +
Sbjct 437 MGCKFRLSAKNDYGVSDFSEEVLYYTSGCAPSVPASPVLTKAGVTWLSLQWTKPSGTPSD 496
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
+ + + ++ ++ + Y NL S Y V ++G +P +
Sbjct 497 EGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVE 556
Query 513 Y-LKQAPPSKG--PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAV 568
+ P P+V+ K + + + WD P D I Y + GN+ +
Sbjct 557 FSTCPDKPGVPVKPSVKGK-IHSHGFKITWDP-PKDNGGAPINKYVVEMAEGSNGNKWDM 614
Query 569 NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF-TTPKFAQG 616
+ E+ LT Y +R+ +D G E TP G
Sbjct 615 IYSGTTREHLCDRLTPGCYYRLRVYCISDGGQSAVSESLLVQTPAVPPG 663
Score = 121 bits (302), Expect = 2e-26, Method: Composition-based stats.
Identities = 81/530 (15%), Positives = 162/530 (31%), Gaps = 37/530 (7%)
Query 80 TIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCI---- 135
+I + D + + Q+ +++ P P C+
Sbjct 613 DMIYSGTTREHLCDRLTPGCYYRLRVYCISDGGQSAVSESLLVQTPAVPPG--PCLPPRL 670
Query 136 --VNEGKKMRCEWDGGRETHLETNFTLKSE-WATHKFADCKAKRDTPTSCTVDYSTVYFV 192
+ K+++ W + E K + + CTV S +
Sbjct 671 QGRPKAKEIQLRWGPPQVDGGSPISCYAVEMTPADKDEPRDVYQGSEVECTV-GSLLPGK 729
Query 193 NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV 252
+ A N +G P+ V ++ ++ W P
Sbjct 730 TYSFRLRAANRIGFGPFSEKYDITTAPGPPDQCRPPQVTCR--SATCAQVNWEIPLSNGT 787
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ +Y +++ + S S ++ L P T Y R++ M G G +
Sbjct 788 DVTEYRLEWGGVEGSMQMCYC-----GPGLSCELKGLSPATTYYCRVQAMSVVGAGPF-- 840
Query 313 WSEEASGITYEDRPSKAPSFWYK----IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
SE + +T P+ I+ H + + WK P++ +IL Y +
Sbjct 841 -SEVVACVTPPSVPAIVTCLQEISDDDIEYPHYSPSTCLAISWKE--PYDHGSEILAYSI 897
Query 369 TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPV 427
L K L + + + + Y + N +G + + + P
Sbjct 898 DLGD-KQPLTVGKMTSYIIDSLQPDTTYRIRIQALNSLGAGPFSHTIKLKTKPLPPDPPR 956
Query 428 MDLKAFPKDNMLWVEWT--TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
++ AF N L ++W TP+ + + D+ + TY
Sbjct 957 LECVAFNHQN-LKLKWGEGTPKTLSTDAVQYHLQMEDRNGRFVSLYRGPCH---TYKVQR 1012
Query 486 LAESKCYLITVTPVYADGPGSPESIKAYL-KQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
L+ES Y + G G + ++ P+ + +K+ + + W+ L
Sbjct 1013 LSESTSYKFCIQACNEAGEGPLSQEYVFTTPKSLPAALKAPKIEKINDHICEITWEYLQP 1072
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
+ I Y + +E T + SSL + Y R+ A
Sbjct 1073 MKGDPVI--YNLQVMVGKDSEFKQIYKGPDTSFRYSSLQLNCEYRFRVCA 1120
Score = 58.3 bits (139), Expect = 3e-07, Method: Composition-based stats.
Identities = 44/232 (19%), Positives = 75/232 (32%), Gaps = 21/232 (9%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLET---NFTLKSEWATHKFADCKAKRDTPT 180
LPP+ P+ L C+ + ++ +W G L T + L+ E +F P
Sbjct 950 LPPDPPR-LECVAFNHQNLKLKWGEGTPKTLSTDAVQYHLQMEDRNGRFVSLYR---GPC 1005
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
+ + ++A N G+ K P + + I
Sbjct 1006 HTYKVQRLSESTSYKFCIQACNEAGEGPLSQEYVFTTPKSLPAALKAPKIEKINDH--IC 1063
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI- 299
++TW + YN+Q S + QI +SF L+ EY FR+
Sbjct 1064 EITWEYLQPMKGDPVIYNLQVMVGKDSEFKQIY----KGPDTSFRYSSLQLNCEYRFRVC 1119
Query 300 ---RCMKEDGK-GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV 347
+C G +S I+ P P+ K + RT+
Sbjct 1120 AIRQCQDPTGHQDLVGPYSTTVFFISQRTEP---PASSNKDSVDSARTRRTL 1168
>sp|Q99MF4|I11RA_RAT Interleukin-11 receptor subunit alpha OS=Rattus
norvegicus OX=10116 GN=Il11ra1 PE=2 SV=1
Length=431
Score = 152 bits (383), Expect = 2e-38, Method: Composition-based stats.
Identities = 56/253 (22%), Positives = 95/253 (38%), Gaps = 30/253 (12%)
Query 94 IASLNIQLTCNILTFGQLEQNVYG--ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRE 151
+A ++ + + + V+G +T+ G PP +P+ +SC + + C W GR
Sbjct 81 LAQVDSRDEGTYVC--RTLDGVFGGMVTLKLGSPPARPE-VSCQAVDYENFSCTWSPGRV 137
Query 152 THLETNFTLKSEWATHKFADCKAKRD--TPTSCTVD---------YSTVYFVNIEVWVEA 200
+ L T + T A+ + + P C D + ++ + V
Sbjct 138 SGLPTRYLTSYRKKTLPGAESQRESPSTGPWPCPQDPLEASRCVVHGAEFWSEYRINVTE 197
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI---KSVIILKY 257
N LG T ++ ++P+PP L V + L +WT P+ + +LK+
Sbjct 198 VNPLGASTC-LLDVRLQRILRPDPPQGLRVESVPGYPRRLHASWTYPASWRRQPHFLLKF 256
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
+QYR WS + P + D + R+ G WS WS EA
Sbjct 257 RLQYRPAQHPAWSTVEPIGLEE-----LITDAVAGLPHAVRVSARDFLDAGTWSAWSPEA 311
Query 318 SGITYEDRPSKAP 330
G PS P
Sbjct 312 WGT-----PSTGP 319
>sp|Q14626|I11RA_HUMAN Interleukin-11 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL11RA PE=1 SV=2
Length=422
Score = 152 bits (383), Expect = 2e-38, Method: Composition-based stats.
Identities = 51/233 (22%), Positives = 85/233 (36%), Gaps = 21/233 (9%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD 177
+T+ G PP +P +SC + + C W + + L T + T AD + +
Sbjct 105 VTLQLGYPPARPV-VSCQAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLGADSQRRSP 163
Query 178 --TPTSCTVD---------YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH 226
P C D + ++ + V N LG T ++ ++P+PP
Sbjct 164 STGPWPCPQDPLGAARCVVHGAEFWSQYRINVTEVNPLGASTR-LLDVSLQSILRPDPPQ 222
Query 227 NLSVINSEELSSILKLTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
L V + L+ +WT P+ + +LK+ +QYR WS + P
Sbjct 223 GLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEE---- 278
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ D + R+ G WS WS EA G K W ++
Sbjct 279 -VITDAVAGLPHAVRVSARDFLDAGTWSTWSPEAWGTPSTGTIPKEIPAWGQL 330
>sp|Q53EP0|FND3B_HUMAN Fibronectin type III domain-containing
protein 3B OS=Homo sapiens OX=9606 GN=FNDC3B PE=1 SV=2
Length=1204
Score = 157 bits (397), Expect = 6e-38, Method: Composition-based stats.
Identities = 90/511 (18%), Positives = 147/511 (29%), Gaps = 49/511 (10%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCTV 184
PE P + +W + + TN+ L+ D + C
Sbjct 379 PECPFPPKLAHRSKSSLTLQWKAPIDNGSKITNYLLE--------WDEGKRNSGFRQCFF 430
Query 185 DYSTVYFVN-------IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
+ + A N +G P P ++ +
Sbjct 431 GSQKHCKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGI-- 488
Query 238 SILKLTWTNP---SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ + L W+ P S + VI IQ D + ED TV++LK T+
Sbjct 489 TWVTLQWSKPEGCSPEEVITYTLEIQEDENDNLFHPKYTGEDLT-----CTVKNLKRSTQ 543
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y FR+ +GK S SE T DRP P+ P + G+ + W
Sbjct 544 YKFRLTASNTEGK---SCPSEVLVCTTSPDRP-GPPTRPLVKGPVTSHGFS---VKWDP- 595
Query 355 PPFEANGKILDYEVTLTRWKSHLQN----YTVNATKLTVNLTNDRYLATLTVRN-LVGKS 409
P +IL Y + +T S Y+ +AT+ T L L G
Sbjct 596 PKDNGGSEILKYLLEITDGNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRACCISTGGH 655
Query 410 DAAVLTIPACDFQATHP---VMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
++P + PK + +EW P + E+ V +
Sbjct 656 SQCSESLPVRTLSIAPGQCRPPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTEPED 715
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVR 526
+ + GNL Y V + G G + A P
Sbjct 716 VASEVYHGPELE--CTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCKAP 773
Query 527 TKKVGKN-EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
+ ++ W+ D I Y + + + + T + + L
Sbjct 774 CISCTPDGCVLVGWES--PDSSGADISEYRLEWGE-DEESLELIYHGTDTRFEIRDLLPA 830
Query 586 TLYMVRMAAYTDEGGKDGPEFTFT-TPKFAQ 615
Y R+ A+ G E TP A
Sbjct 831 AQYCCRLQAFNQAGAGPYSELVLCQTPASAP 861
Score = 156 bits (393), Expect = 2e-37, Method: Composition-based stats.
Identities = 95/517 (18%), Positives = 159/517 (31%), Gaps = 51/517 (10%)
Query 107 TFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG--GRETHLETNFTLKSEW 164
T G ++ V P P+ + + +W G +TL+ +
Sbjct 459 TSGYSQEVVCYTLGNIPQMPSAPRLV---RAGITWVTLQWSKPEGCSPEEVITYTLEIQE 515
Query 165 ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNP 224
+ +CTV + + + A N GK + +P P
Sbjct 516 DENDNLFHPKYTGEDLTCTV-KNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGP 574
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P V S + W P ILKY ++ D ++ + + + +
Sbjct 575 PTRPLVKG-PVTSHGFSVKWDPPKDNGGSEILKYLLE--ITDGNSEANQWEVAYSGSATE 631
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+T LKP T Y R C+ G S SE T P + P H
Sbjct 632 YTFTHLKPGTLYKLRACCISTGGH---SQCSESLPVRTLSIAPGQCRPPRVLGRPKH--- 685
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV----NLTNDRYLAT 399
+ V L W +P E+ ++ +Y V +T + +L L Y
Sbjct 686 -KEVHLEWD-VPASESGCEVSEYSVEMTEPEDVASEVYH-GPELECTVGNLLPGTVYRFR 742
Query 400 LTVRNLVGKSD-AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP---RESVKKYIL 455
+ N G + V I + D + V W +P + +Y L
Sbjct 743 VRALNDGGYGPYSDVSEITTAAGPPGQCKAPCISCTPDGCVLVGWESPDSSGADISEYRL 802
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYL 514
EW + I GT R +R L + Y + G G E +
Sbjct 803 EWGEDEESLELIYH-----GTDTRFEIRD-LLPAAQYCCRLQAFNQAGAGPYSELVLCQT 856
Query 515 KQAPPSKGPTVRTKKVGK---------NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE 565
+ P T+ + VL W++ I YTI +
Sbjct 857 PASAPDPVSTLCVLEEEPLDAYPDSPSACLVLNWEE--PCNNGSEILAYTI-----DLGD 909
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
T++ V + T + + L +T Y +R+ A + G
Sbjct 910 TSITV-GNTTMHVMKDLLPETTYRIRIQAINEIGAGP 945
Score = 134 bits (336), Expect = 1e-30, Method: Composition-based stats.
Identities = 86/515 (17%), Positives = 156/515 (30%), Gaps = 46/515 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSC 182
PP +P L +WD ++ + L+ + + +
Sbjct 574 PPTRP--LVKGPVTSHGFSVKWDPPKDNGGSEILKYLLEITDGNSEANQWEVAYSGSATE 631
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
++ + G + P V+ + + L
Sbjct 632 YTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSIAPGQCRPPRVLGRPKHK-EVHL 690
Query 243 TWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
W P+ +S + +Y+++ + + E TV +L P T Y FR+R
Sbjct 691 EWDVPASESGCEVSEYSVEM-----TEPEDVASEVYHGPELECTVGNLLPGTVYRFRVRA 745
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ + G G +SD SE T P + + P V + W+ P +
Sbjct 746 LNDGGYGPYSDVSE---ITTAAGPPGQCKAPCISCTPDGC-----VLVGWE--SPDSSGA 795
Query 362 KILDYEVTLTRWKSHLQNYTV-NATKLTVN--LTNDRYLATLTVRNLVGKSDAAVLTIPA 418
I +Y + + L+ T+ + L +Y L N G + L +
Sbjct 796 DISEYRLEWGEDEESLELIYHGTDTRFEIRDLLPAAQYCCRLQAFNQAGAGPYSELVLCQ 855
Query 419 CDFQATHPVMD--------LKAFP--KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCIT 468
A PV L A+P L + W P + + IL + +
Sbjct 856 TPASAPDPVSTLCVLEEEPLDAYPDSPSACLVLNWEEPCNNGSE-ILAYTIDLGDTS--- 911
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTK 528
++ +L Y I + + G G + P P +
Sbjct 912 ----ITVGNTTMHVMKDLLPETTYRIRIQAINEIGAGPFSQFIKAKTRPLPPLPPRLECA 967
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV-DSSHTEYTLSSLTSDTL 587
G L+W YT+ + N+ +++ Y + LT T
Sbjct 968 AAGPQSLKLKWGDSNSKTHAAEDIVYTL--QLEDRNKRFISIYRGPSHTYKVQRLTEFTC 1025
Query 588 YMVRMAAYTDEGGKDGPEF-TFTTPKFAQGEIEAI 621
Y R+ A ++ G E TF+T K I+A
Sbjct 1026 YSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAP 1060
Score = 133 bits (335), Expect = 2e-30, Method: Composition-based stats.
Identities = 76/406 (19%), Positives = 124/406 (31%), Gaps = 38/406 (9%)
Query 233 SEELSSILKLTWTNP-------SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
S + + L+W P Y + K +I +
Sbjct 285 SNIQARAVVLSWAPPVGLSCGPHSGLSFPYSYEVALSDKGRDGKYKIIY---SGEELECN 341
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA-PSFWYKIDPSHTQGY 344
++DL+P T+Y R+ M KG SE S T+ P P +
Sbjct 342 LKDLRPATDYHVRVYAMYNSVKGSC---SEPVSFTTHSCAPECPFPPKLAH------RSK 392
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN-----YTVNATKLTVNLTNDRYLAT 399
++ L WK P + KI +Y + K + + KLT Y
Sbjct 393 SSLTLQWKA--PIDNGSKITNYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLCPAMGYTFR 450
Query 400 LTVRNLVGKSDAAVLTIP---ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
L RN +G S + + Q ++A + ++W+ P + ++
Sbjct 451 LAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRA--GITWVTLQWSKPEGCSPEEVIT 508
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA-YLK 515
+ + + + + T NL S Y +T +G P +
Sbjct 509 YTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTS 568
Query 516 QAPPSKGPTVRTK-KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET--AVNVDS 572
P K V + ++WD P D I Y + V
Sbjct 569 PDRPGPPTRPLVKGPVTSHGFSVKWDP-PKDNGGSEILKYLLEITDGNSEANQWEVAYSG 627
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF-TFTTPKFAQGE 617
S TEYT + L TLY +R + G E T A G+
Sbjct 628 SATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSIAPGQ 673
Score = 122 bits (305), Expect = 7e-27, Method: Composition-based stats.
Identities = 84/531 (16%), Positives = 160/531 (30%), Gaps = 46/531 (9%)
Query 83 NRTASSVTFTDI---ASLNIQLTCNILTFGQLEQNVYGITIISGLP--PEKPKNLSCIVN 137
+ +A+ TFT + ++ C + +S P P+ L
Sbjct 626 SGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSIAPGQCRPPRVLG--RP 683
Query 138 EGKKMRCEWD-GGRETHLETN-FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIE 195
+ K++ EWD E+ E + ++++ ++ P + +
Sbjct 684 KHKEVHLEWDVPASESGCEVSEYSVEMTEPEDVASEVYH---GPELECTVGNLLPGTVYR 740
Query 196 VWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
V A N G ++ P + + + + + W +P I
Sbjct 741 FRVRALNDGGYGPYSDVSEITTAAGPPGQCKAPCISCTPD--GCVLVGWESPDSSGADIS 798
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+Y ++ + T + F ++DL P +Y R++ + G G +SE
Sbjct 799 EYRLE-----WGEDEESLELIYHGTDTRFEIRDLLPAAQYCCRLQAFNQAGAG---PYSE 850
Query 316 EASGITYEDRPSKAPSF----WYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
T P + +D + L W+ P +IL Y + L
Sbjct 851 LVLCQTPASAPDPVSTLCVLEEEPLDAYPDSPSACLVLNWEE--PCNNGSEILAYTIDLG 908
Query 372 RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
+ N T+ + L Y + N +G + P
Sbjct 909 DTSITVGNTTM--HVMKDLLPETTYRIRIQAINEIGAGPFSQFIKAKTRPLPPLPPRLEC 966
Query 432 AFPKDNMLWVEW------TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
A L ++W T E + + L D+ + TY
Sbjct 967 AAAGPQSLKLKWGDSNSKTHAAEDIVYTLQ----LEDRNKRFISIYRGPSH---TYKVQR 1019
Query 486 LAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
L E CY + G G E+ ++ P R ++ N + W+ +P
Sbjct 1020 LTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAPRVTQLEGNSCEILWETVPS 1079
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
G NY + +E + +S L ++T Y R+ A
Sbjct 1080 MK--GDPVNYILQVLVGRESEYKQVYKGEEATFQISGLQTNTDYRFRVCAC 1128
Score = 48.7 bits (114), Expect = 3e-04, Method: Composition-based stats.
Identities = 32/177 (18%), Positives = 60/177 (34%), Gaps = 18/177 (10%)
Query 134 CIVNEGKKMRCEW-DGGRETHL--ETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY 190
C + ++ +W D +TH + +TL+ E +F P+
Sbjct 966 CAAAGPQSLKLKWGDSNSKTHAAEDIVYTLQLEDRNKRFISIYR---GPSHTYKVQRLTE 1022
Query 191 FVNIEVWVEAENALGKVT-SDHINFDPVYKVKP--NPPHNLSVINSEELSSILKLTWTNP 247
F ++A + G+ S+ F V P P V E S ++ W
Sbjct 1023 FTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAP---RVTQLEGNS--CEILWETV 1077
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ Y +Q S + Q+ ++F + L+ T+Y FR+ +
Sbjct 1078 PSMKGDPVNYILQVLVGRESEYKQVY----KGEEATFQISGLQTNTDYRFRVCACRR 1130
>sp|Q64385|I11RA_MOUSE Interleukin-11 receptor subunit alpha-1
OS=Mus musculus OX=10090 GN=Il11ra1 PE=1 SV=1
Length=432
Score = 150 bits (378), Expect = 1e-37, Method: Composition-based stats.
Identities = 55/280 (20%), Positives = 95/280 (34%), Gaps = 24/280 (9%)
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH 153
+A ++ + + +T+ G PP +P+ +SC + + C W G+ +
Sbjct 81 LAQVDSPDEGTYVCQTLDGVSGGMVTLKLGFPPARPE-VSCQAVDYENFSCTWSPGQVSG 139
Query 154 LETNFTLKSEWATHKFADCKAKRD--TPTSCTVD---------YSTVYFVNIEVWVEAEN 202
L T + T A+ + + P C D + ++ + V N
Sbjct 140 LPTRYLTSYRKKTLPGAESQRESPSTGPWPCPQDPLEASRCVVHGAEFWSEYRINVTEVN 199
Query 203 ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI---KSVIILKYNI 259
LG T ++ ++P+PP L V + L +WT P+ + +LK+ +
Sbjct 200 PLGASTC-LLDVRLQSILRPDPPQGLRVESVPGYPRRLHASWTYPASWRRQPHFLLKFRL 258
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
QYR WS + P + D + R+ G WS WS EA G
Sbjct 259 QYRPAQHPAWSTVEPIGLEE-----VITDAVAGLPHAVRVSARDFLDAGTWSAWSPEAWG 313
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
W + H Q V + P
Sbjct 314 TPSTGPLQDEIPDWSQG---HGQQLEAVVAQEDSPAPARP 350
>sp|Q02388|CO7A1_HUMAN Collagen alpha-1(VII) chain OS=Homo sapiens
OX=9606 GN=COL7A1 PE=1 SV=2
Length=2944
Score = 156 bits (395), Expect = 2e-37, Method: Composition-based stats.
Identities = 98/648 (15%), Positives = 184/648 (28%), Gaps = 75/648 (12%)
Query 57 YFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIA-SLNIQLTCNILTFGQLEQNV 115
+ W+ P ++ + + + +LT L G E
Sbjct 438 VPEARGYRLEWRRETGLEPPQKVVLPSDVT-RYQLDGLQPGTEYRLTLYTLLEGH-EVAT 495
Query 116 YGITIISG--LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCK 173
+ +G LP +L G+++R W + ++S +
Sbjct 496 PATVVPTGPELPVSPVTDLQATELPGQRVRVSWSP-VPGATQYRIIVRSTQGVERTLVLP 554
Query 174 AKRDTPTSCTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
D V ++ V V A + ++ + + P V++
Sbjct 555 GS-----QTAFDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVS 609
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
++ +++ W S + I + T SQ P D+ +T + L+P
Sbjct 610 D---ATRVRVAWGPVPGASG----FRISWSTGSGPESSQTLPPDSTAT----DITGLQPG 658
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
T Y + ++ +G A+ I P + +V + W
Sbjct 659 TTYQVAVSVLRGREEG-------PAAVIVARTDPLGPVRTVHV----TQASSSSVTITWT 707
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN----DRYLATLTVRNLVGK 408
+P Y V+ ++ V+ L Y +
Sbjct 708 RVPGA------TGYRVSWHSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVD 761
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCIT 468
A + + ++L + W + Y L W
Sbjct 762 GPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGAT-AYRLAW---GRSEGGPM 817
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTK 528
Q G +RG L Y + VT + D G+P SI P T+
Sbjct 818 RHQILPGNTDSAEIRG-LEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVV 876
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLY 588
+ G++ L W+ +P + + + ++ G E + + + Y L L T Y
Sbjct 877 QRGEHSLRLRWEPVPR------AQGFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQY 930
Query 589 MVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIK 648
VR++ G E T T IE VV + + V
Sbjct 931 RVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSR--------- 981
Query 649 KHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQ-MYSDGNFTDVSVVE 695
+ S+I W P P Q + + V+ +E
Sbjct 982 ----------ASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLE 1019
Score = 127 bits (318), Expect = 2e-28, Method: Composition-based stats.
Identities = 65/420 (15%), Positives = 131/420 (31%), Gaps = 50/420 (12%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPE 275
V + P P +V ++ SS + +TWT + YR S +
Sbjct 679 IVARTDPLGPVR-TVHVTQASSSSVTITWTRVPGATG--------YRVSWHSAHGPEKSQ 729
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
+ + + L+P TEY +R G + E P S
Sbjct 730 LVSGEATVAELDGLEPDTEYTVHVRAHVA---GVDGPPASVVVRTAPE--PVGRVSRLQI 784
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY---TVNATKLTVNLT 392
++ S +++ W + A Y + R + + N +
Sbjct 785 LNASSD----VLRITWVGVTGATA------YRLAWGRSEGGPMRHQILPGNTDSAEIRGL 834
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK--AFPKDNMLWVEWTTPRESV 450
++ V LVG + ++I P + ++ L + W +
Sbjct 835 EGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRA- 893
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
+ ++L W + + G +Y L + Y + ++ + G G +
Sbjct 894 QGFLLHWQPEGGQEQS-----RVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEV 948
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV-- 568
A ++P +R + L W + +Y + +R + G V
Sbjct 949 TART-ESPRVPSIELRVVDTSIDSVTLAWTPV------SRASSYILSWRPLRGPGQEVPG 1001
Query 569 ---NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT-TPKFAQGEIEAIVVP 624
+ + ++ L Y+ + D G GPE + T TP +G + + +P
Sbjct 1002 SPQTLPGISSSQRVTGLEPGVSYIFSLTPVLD--GVRGPEASVTQTPVCPRGLADVVFLP 1059
Score = 121 bits (304), Expect = 1e-26, Method: Composition-based stats.
Identities = 72/502 (14%), Positives = 146/502 (29%), Gaps = 65/502 (13%)
Query 120 IISGLPPE----KPKNLSCIVNEGKKMRCEWDG--GRETHLETNFT-LKSEWATHKFADC 172
+ PP+ P++L + +R +W G T + +T L
Sbjct 222 VPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQ 281
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEA--ENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
+ + +V V A N++G+ S + +
Sbjct 282 EVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALE--------GPEL 333
Query 231 INSEELSSILKLTWTN-PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
+ L + W + P Y + +R Q ++ + S ++DL
Sbjct 334 TIQNTTAHSLLVAWRSVPGA-----TGYRVTWRVLSGGPTQQ---QELGPGQGSVLLRDL 385
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
+P T+Y + + G + T G ++ L
Sbjct 386 EPGTDYEVTVSTLFGRSVG----PATSLMARTDASVEQTLRPV--------ILGPTSILL 433
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNY----TVNATKLTVNLTNDRYLATLTVRNL 405
W +P Y + R + T+ ++ LT+ L
Sbjct 434 SWNLVPEA------RGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTL 487
Query 406 VGKSDAAV--LTIPACDFQATHPVMDLKAFPKDN-MLWVEWTTPRESVKKYILEWCVLSD 462
+ + A +P PV DL+A + V W+ + + + ++
Sbjct 488 LEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGATQ-----YRIIVR 542
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+ G+ L ++ Y + V+ GS + + P
Sbjct 543 STQGVERTLVLPGSQTAFDL-DDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAV 601
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
P +R + W +P + I + T G E++ + T ++ L
Sbjct 602 PGLRVVVSDATRVRVAWGPVPGAS------GFRISWSTGSGPESSQTLPPDSTATDITGL 655
Query 583 TSDTLYMVRMAAYTDEGGKDGP 604
T Y V ++ G ++GP
Sbjct 656 QPGTTYQVAVSVL--RGREEGP 675
Score = 107 bits (267), Expect = 3e-22, Method: Composition-based stats.
Identities = 61/292 (21%), Positives = 98/292 (34%), Gaps = 43/292 (15%)
Query 320 ITYEDRPSKAPSFWYKIDPS----HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK- 374
T P P P +++++ W A+G + Y+V T
Sbjct 217 TTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQW-----TAASGPVTGYKVQYTPLTG 271
Query 375 ------SHLQNYTVNATKLTVNLTN----DRYLATLTV--RNLVGKSDAAVLTIPACDFQ 422
S Q V A + +V L Y T+ N +G++ + A +
Sbjct 272 LGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP 331
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
+ L V W + + Y + W VLS QQE G + L
Sbjct 332 ELTIQNT-----TAHSLLVAWRSVPGAT-GYRVTWRVLSGGPTQ----QQELGPGQGSVL 381
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
+L Y +TV+ ++ G S+ A S T+R +G +L W+ +
Sbjct 382 LRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDA---SVEQTLRPVILGPTSILLSWNLV 438
Query 543 PVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRM 592
P R Y + +R G E V + S T Y L L T Y + +
Sbjct 439 P------EARGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTL 484
Score = 92.2 bits (227), Expect = 1e-17, Method: Composition-based stats.
Identities = 45/230 (20%), Positives = 73/230 (32%), Gaps = 17/230 (7%)
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS---DKA 464
+ V D + P + + P L V+WT V Y +++ L+
Sbjct 217 TTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPL 276
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
P LRG L Y +TV +YA+ G S A +GP
Sbjct 277 PSERQEVNVPAGETSVRLRG-LRPLTEYQVTVIALYANSIGEAVSGTART---TALEGPE 332
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI-IGNETAVNVDSSHTEYTLSSLT 583
+ + + ++ W +P Y + +R + G + L L
Sbjct 333 LTIQNTTAHSLLVAWRSVPG------ATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLE 386
Query 584 SDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA-IVVPVCLAFLLT 632
T Y V + T G GP + A E V+ + LL+
Sbjct 387 PGTDYEVTV--STLFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLS 434
Score = 87.6 bits (215), Expect = 5e-16, Method: Composition-based stats.
Identities = 71/494 (14%), Positives = 146/494 (30%), Gaps = 54/494 (11%)
Query 32 SPESPVVQLHSNFTAVCVLKEKCM--DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSV 89
PE+P+ + + + I W T Q + TA+ +
Sbjct 594 EPETPLAVPGLRVVVSDATRVRVAWGPVPGASGFRISWSTGSGP-ESSQTLPPDSTATDI 652
Query 90 T-FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD- 147
T + + ++ E+ + + P + + + W
Sbjct 653 TGLQPGTTYQVAVS----VLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTR 708
Query 148 -GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK 206
G + + W + + + V V A + G
Sbjct 709 VPGATGY-------RVSWHSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRA-HVAGV 760
Query 207 VTSDHINFDPVYKVKPNPPHNLS-VINSEELSSILKLTWTNPSIKSVIILKYNIQY-RTK 264
D V + P P +S + S +L++TW + Y + + R++
Sbjct 761 ---DGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGA----TAYRLAWGRSE 813
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
QI P S ++ L+ Y R+ + D +G T +
Sbjct 814 GGPMRHQILP----GNTDSAEIRGLEGGVSYSVRVTALVGDREGTP----VSIVVTTPPE 865
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA 384
P A + + +G +++L W+ +P + + Q+ +
Sbjct 866 AP-PALGTLHVV----QRGEHSLRLRWEPVPRA------QGFLLHWQPEGGQEQSRVLGP 914
Query 385 TKLTVNLTN----DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD-NML 439
+ +L +Y L+V G+ +A + A P ++L+ + +
Sbjct 915 ELSSYHLDGLEPATQYRVRLSVLGPAGEGPSA--EVTARTESPRVPSIELRVVDTSIDSV 972
Query 440 WVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPV 499
+ WT + YIL W L + Q + + L Y+ ++TPV
Sbjct 973 TLAWTPVSRASS-YILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPV 1031
Query 500 YADGPGSPESIKAY 513
G S+
Sbjct 1032 LDGVRGPEASVTQT 1045
>sp|P70225|I11RB_MOUSE Interleukin-11 receptor subunit alpha-2
OS=Mus musculus OX=10090 GN=Il11ra2 PE=2 SV=4
Length=432
Score = 148 bits (374), Expect = 4e-37, Method: Composition-based stats.
Identities = 56/280 (20%), Positives = 96/280 (34%), Gaps = 24/280 (9%)
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH 153
+A ++ + + +T+ G PP +P+ +SC + + C W G+ +
Sbjct 81 LAQVDSPDEGTYVCQTLDGVSGGMVTLKLGFPPARPE-VSCQAVDYENFSCTWSPGQVSG 139
Query 154 LETNFTLKSEWATHKFADCKAKRD--TPTSCTVD---------YSTVYFVNIEVWVEAEN 202
L T + T A+ + + P C D + ++ + V N
Sbjct 140 LPTRYLTSYRKKTLPGAESQRESPSTGPWPCPQDPLEASRCVVHGAEFWSEYRINVTEVN 199
Query 203 ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI---KSVIILKYNI 259
LG T ++ ++P+PP L V + L +WT P+ + +LK+ +
Sbjct 200 PLGASTC-LLDVRLQSILRPDPPQGLRVESVPGYPRRLHASWTYPASWRRQPHFLLKFRL 258
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
QYR WS + P + D + R+ G WS WS EA G
Sbjct 259 QYRPAQHPAWSTVEPIGLEE-----VITDTVAGLPHAVRVSARDFLDAGTWSAWSPEAWG 313
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
W + H Q V +L P
Sbjct 314 TPSTGLLQDEIPDWSQG---HGQQLEAVVAQEDSLAPARP 350
>sp|Q9Y2H6|FND3A_HUMAN Fibronectin type-III domain-containing
protein 3A OS=Homo sapiens OX=9606 GN=FNDC3A PE=1 SV=4
Length=1198
Score = 154 bits (389), Expect = 6e-37, Method: Composition-based stats.
Identities = 89/491 (18%), Positives = 147/491 (30%), Gaps = 47/491 (10%)
Query 141 KMRCEWDG-----------GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
+ W L L S + D
Sbjct 281 TVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPA 340
Query 190 YFVNIEVWVEAE-NALGKVTSDHINFDPVYKVK--PNPPHNLSVINSEELSSILKLTWTN 246
+ V+AE N++ S+ F + PNPP + + L L W
Sbjct 341 M--DYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPR-----IANRTKNSLTLQWKA 393
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
PS I + +++ D + + ++ F + L P FR+ + G
Sbjct 394 PSDNGSKIQNFVLEW---DEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYG 450
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILD 365
+ SEE T PS P T+ T + L W + + +
Sbjct 451 TSGF---SEEVLYYTSGCAPSMP------ASPVLTKAGITWLSLQWSKPSGT-PSDEGIS 500
Query 366 YEVTLTRWKSH---LQNYTVNATKLTV--NLTNDRYLATLTVRNLVGKS-DAAVLTIPAC 419
Y + + S Y TV + +Y + N GKS + V+ C
Sbjct 501 YILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTC 560
Query 420 DFQATHPVM-DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
+ PV +K + + W P+++ I ++ V + W+
Sbjct 561 PDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGAT 620
Query 479 RTYLRGNLAESKCYLITVTPVYADGP-GSPESIKAYLKQAPPSK--GPTVRTKKVGKNEA 535
R +L L Y + V + G ES+ PP P ++ + E
Sbjct 621 REHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQG-RPKAKEI 679
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
L W P+ I Y++ I +E S E T+SSL Y R+ A
Sbjct 680 QLRWGP-PLVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGKTYSFRLRAA 738
Query 596 TDEGGKDGPEF 606
G E
Sbjct 739 NKMGFGPFSEK 749
Score = 151 bits (382), Expect = 4e-36, Method: Composition-based stats.
Identities = 80/522 (15%), Positives = 152/522 (29%), Gaps = 54/522 (10%)
Query 126 PEKPKNLSCIVN-EGKKMRCEWDGGRETHLET--NFTLKSEWA--THKFADCKAKRDTPT 180
P P S + WD ++ T + ++ +K+ +
Sbjct 564 PGIPVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGATREH 623
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
C + + V + G+ V P P + + +
Sbjct 624 LCDRLNPGCF---YRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAK-EI 679
Query 241 KLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+L W P I Y+++ + ++ + TV L P Y FR+
Sbjct 680 QLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQ----GSEVECTVSSLLPGKTYSFRL 735
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPS--KAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
R + G G + SE+ T P K P + + W+
Sbjct 736 RAANKMGFGPF---SEKCDITTAPGPPDQCKPPQVTCRSATCAQ-------VNWEVP--- 782
Query 358 EANG-KILDYEVTLTRWKSHLQN---YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAV 413
+NG + +Y + + +Q + ++ Y + ++VG +
Sbjct 783 LSNGTDVTEYRLEWGGVEGSMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPFSE 842
Query 414 LTIPACDFQATHPVMDLKA----------FPKDNMLWVEWTTPRESVKKYILEWCVLSDK 463
+ V L+ + L + W P + + IL + +
Sbjct 843 VVACVTPPSVPGIVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSE-ILAYSIDFGD 901
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKG 522
+T +Y+ NL Y I + + + G G IK K PP
Sbjct 902 KQSLT------VGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPD-P 954
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
P + L+W + + Y + G ++ Y + L
Sbjct 955 PRLECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSL-YRGPCHTYKVQRL 1013
Query 583 TSDTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVV 623
T Y + A + G E+ FTTPK ++A +
Sbjct 1014 NESTSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAALKAPKI 1055
Score = 121 bits (303), Expect = 1e-26, Method: Composition-based stats.
Identities = 82/530 (15%), Positives = 163/530 (31%), Gaps = 39/530 (7%)
Query 81 IINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCI----- 135
+I A+ D + + Q+ +++ P P C+
Sbjct 614 MIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPG--PCLPPRLQ 671
Query 136 -VNEGKKMRCEWDGGRETHLETNFTLKSE-WATHKFADCKAKRDTPTSCTVDYSTVYFVN 193
+ K+++ W E K + + + CTV
Sbjct 672 GRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGK-T 730
Query 194 IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI 253
+ A N +G P+ V ++ ++ W P
Sbjct 731 YSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCR--SATCAQVNWEVPLSNGTD 788
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ +Y +++ + S S+ ++ L P T Y R++ + G G +
Sbjct 789 VTEYRLEWGGVEGSMQICYC-----GPGLSYEIKGLSPATTYYCRVQALSVVGAGPF--- 840
Query 314 SEEASGITYEDRPS-----KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
SE + +T P + S +P H + + W+ P + +IL Y +
Sbjct 841 SEVVACVTPPSVPGIVTCLQEISDDEIENP-HYSPSTCLAISWEK--PCDHGSEILAYSI 897
Query 369 TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPV 427
+S L V + + + Y + N +G + ++ + P
Sbjct 898 DFGDKQS-LTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPR 956
Query 428 MDLKAFPKDNMLWVEWT--TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
++ AF N L ++W TP+ I + DK + TY
Sbjct 957 LECVAFSHQN-LKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCH---TYKVQR 1012
Query 486 LAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
L ES Y + G G + ++ P+ + +KV + + W+ L
Sbjct 1013 LNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQP 1072
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
+ I Y++ +E + + SSL + Y R+ A
Sbjct 1073 MKGDPVI--YSLQVMLGKDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCA 1120
Score = 118 bits (295), Expect = 1e-25, Method: Composition-based stats.
Identities = 70/407 (17%), Positives = 134/407 (33%), Gaps = 31/407 (8%)
Query 228 LSVINSEELSSILKLTWTNPS-------IKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
+ + S+ + + LTW+ PS +S + Y + +
Sbjct 270 VKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYK-SVYVGE 328
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
++ T+ DLKP +Y +++ KG SE T P P+ + +
Sbjct 329 ETNITLNDLKPAMDYHAKVQAEYNSIKGT---PSEAEIFTTLSCEPD-IPNPPRIANRTK 384
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ-----NYTVNATKLTVNLTNDR 395
++ L WK P + KI ++ + K + + + K+T
Sbjct 385 N----SLTLQWKA--PSDNGSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMG 438
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATH-PVMDLKAFPKDNMLWVEWTTPRESVKKYI 454
L+ RN G S + + A P + L ++W+ P +
Sbjct 439 CKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEG 498
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+ + + ++ ++ + Y NL S Y V ++G +P + +
Sbjct 499 ISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFT 558
Query 515 K-QAPPSKG--PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAVNV 570
P P+V+ K + + + WD P D I Y + GN+ +
Sbjct 559 TCPDKPGIPVKPSVKGK-IHSHSFKITWDP-PKDNGGATINKYVVEMAEGSNGNKWEMIY 616
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF-TTPKFAQG 616
+ E+ L Y +R+ +D G E TP G
Sbjct 617 SGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPG 663
>sp|Q5RBN1|FND3A_PONAB Fibronectin type-III domain-containing
protein 3A OS=Pongo abelii OX=9601 GN=FNDC3A PE=2 SV=1
Length=1142
Score = 154 bits (389), Expect = 6e-37, Method: Composition-based stats.
Identities = 89/491 (18%), Positives = 147/491 (30%), Gaps = 47/491 (10%)
Query 141 KMRCEWDG-----------GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
+ W L L S + D
Sbjct 225 TVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYIGEETNITLNDLKPA 284
Query 190 YFVNIEVWVEAE-NALGKVTSDHINFDPVYKVK--PNPPHNLSVINSEELSSILKLTWTN 246
+ V+AE N++ S+ F + PNPP + + L L W
Sbjct 285 --TDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPR-----IANRTKNSLTLQWKA 337
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
PS I + +++ D + + ++ F + L P FR+ + G
Sbjct 338 PSDNGSKIQNFVLEW---DEGKGNGEFYQCYMGSQKQFKITKLSPAMGCKFRLSARNDYG 394
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANGKILD 365
+ SEE T PS P T+ T + L W + + +
Sbjct 395 TSGF---SEEVLYYTSGCAPSMP------ASPVLTKAGITWLSLQWSKPSGT-PSDEGIS 444
Query 366 YEVTLTRWKSH---LQNYTVNATKLTV--NLTNDRYLATLTVRNLVGKS-DAAVLTIPAC 419
Y + + S Y TV + +Y + N GKS + V+ C
Sbjct 445 YILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTC 504
Query 420 DFQATHPVM-DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
+ PV +K + + W P+++ I ++ V + W+
Sbjct 505 PDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGAAINKYVVEMAEGSNGNKWEMIYSGAT 564
Query 479 RTYLRGNLAESKCYLITVTPVYADGP-GSPESIKAYLKQAPPSK--GPTVRTKKVGKNEA 535
R +L L Y + V + G ES+ PP P ++ + E
Sbjct 565 REHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQG-RPKAKEI 623
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
L W P+ I Y++ I +E S E T+SSL Y R+ A
Sbjct 624 QLRWGP-PLVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGKTYSFRLRAA 682
Query 596 TDEGGKDGPEF 606
G E
Sbjct 683 NKMGFGPFSEK 693
Score = 152 bits (383), Expect = 3e-36, Method: Composition-based stats.
Identities = 76/521 (15%), Positives = 149/521 (29%), Gaps = 52/521 (10%)
Query 126 PEKPKNLSCIVN-EGKKMRCEWDGGRETHLE--TNFTLKSEWA--THKFADCKAKRDTPT 180
P P S + WD ++ + ++ +K+ +
Sbjct 508 PGIPVKPSVKGKIHSHSFKITWDPPKDNGGAAINKYVVEMAEGSNGNKWEMIYSGATREH 567
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
C + + V + G+ V P P + + +
Sbjct 568 LCDRLNPGCF---YRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAK-EI 623
Query 241 KLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+L W P I Y+++ + ++ + TV L P Y FR+
Sbjct 624 QLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQ----GSEVECTVSSLLPGKTYSFRL 679
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPS--KAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
R + G G + SE+ T P K P + + W+
Sbjct 680 RAANKMGFGPF---SEKCDITTAPGPPDQCKPPQVTCRSATCAQ-------VNWEVP--- 726
Query 358 EANG-KILDYEVTLTRWKSHLQN---YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAV 413
+NG + +Y + + +Q ++ Y + ++VG +
Sbjct 727 LSNGTDVTEYRLEWGGVEGSMQICYCGPGLNYEIKGLSPATTYYCRVQALSVVGAGPFSE 786
Query 414 LTIPACDFQATHPVMDLKA----------FPKDNMLWVEWTTPRESVKKYILEWCVLSDK 463
+ V L+ + L + W P + + IL + + S
Sbjct 787 VVACVTPPSVPGIVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSE-ILAYSIDSGD 845
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
+T +Y+ NL Y I + + + G G + + P P
Sbjct 846 KQSLT------VGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHVIKLKTKPLPPDPP 899
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLT 583
+ L+W + + Y + G ++ Y + L
Sbjct 900 RLECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSL-YRGPCHTYKVQRLN 958
Query 584 SDTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVV 623
T Y + A + G E+ FTTPK ++A +
Sbjct 959 ESTSYKFCIQACNEAGEGPVSQEYIFTTPKSVPAALKAPKI 999
Score = 120 bits (301), Expect = 2e-26, Method: Composition-based stats.
Identities = 82/530 (15%), Positives = 163/530 (31%), Gaps = 39/530 (7%)
Query 81 IINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCI----- 135
+I A+ D + + Q+ +++ P P C+
Sbjct 558 MIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPG--PCLPPRLQ 615
Query 136 -VNEGKKMRCEWDGGRETHLETNFTLKSE-WATHKFADCKAKRDTPTSCTVDYSTVYFVN 193
+ K+++ W E K + + + CTV
Sbjct 616 GRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGK-T 674
Query 194 IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI 253
+ A N +G P+ V ++ ++ W P
Sbjct 675 YSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCR--SATCAQVNWEVPLSNGTD 732
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ +Y +++ + S ++ ++ L P T Y R++ + G G +
Sbjct 733 VTEYRLEWGGVEGSMQICYC-----GPGLNYEIKGLSPATTYYCRVQALSVVGAGPF--- 784
Query 314 SEEASGITYEDRPS-----KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
SE + +T P + S +P H + + W+ P + +IL Y +
Sbjct 785 SEVVACVTPPSVPGIVTCLQEISDDEIENP-HYSPSTCLAISWEK--PCDHGSEILAYSI 841
Query 369 TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPV 427
+ K L V + + + Y + N +G + V+ + P
Sbjct 842 D-SGDKQSLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHVIKLKTKPLPPDPPR 900
Query 428 MDLKAFPKDNMLWVEWT--TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
++ AF N L ++W TP+ I + DK + TY
Sbjct 901 LECVAFSHQN-LKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCH---TYKVQR 956
Query 486 LAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
L ES Y + G G + ++ P+ + +KV + + W+ L
Sbjct 957 LNESTSYKFCIQACNEAGEGPVSQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQP 1016
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
+ I Y++ +E + + SSL + Y R+ A
Sbjct 1017 MKGDPVI--YSLQVMLGKDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCA 1064
Score = 119 bits (299), Expect = 4e-26, Method: Composition-based stats.
Identities = 72/407 (18%), Positives = 136/407 (33%), Gaps = 31/407 (8%)
Query 228 LSVINSEELSSILKLTWTNPS-------IKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
+ + S+ + + LTW+ PS +S + Y + +
Sbjct 214 VKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYI-GE 272
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
++ T+ DLKP T+Y +++ KG SE T P P+ + +
Sbjct 273 ETNITLNDLKPATDYHAKVQAEYNSIKGT---PSEAEIFTTLSCEPD-IPNPPRIANRTK 328
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY-----TVNATKLTVNLTNDR 395
++ L WK P + KI ++ + K + + Y + K+T
Sbjct 329 N----SLTLQWKA--PSDNGSKIQNFVLEWDEGKGNGEFYQCYMGSQKQFKITKLSPAMG 382
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATH-PVMDLKAFPKDNMLWVEWTTPRESVKKYI 454
L+ RN G S + + A P + L ++W+ P +
Sbjct 383 CKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEG 442
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+ + + ++ ++ + Y NL S Y V ++G +P + +
Sbjct 443 ISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFT 502
Query 515 K-QAPPSKG--PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAVNV 570
P P+V+ K + + + WD P D I Y + GN+ +
Sbjct 503 TCPDKPGIPVKPSVKGK-IHSHSFKITWDP-PKDNGGAAINKYVVEMAEGSNGNKWEMIY 560
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF-TTPKFAQG 616
+ E+ L Y +R+ +D G E TP G
Sbjct 561 SGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPG 607
>sp|Q00546|TENR_CHICK Tenascin-R OS=Gallus gallus OX=9031 GN=TNR
PE=1 SV=1
Length=1353
Score = 152 bits (383), Expect = 3e-36, Method: Composition-based stats.
Identities = 100/581 (17%), Positives = 189/581 (33%), Gaps = 70/581 (12%)
Query 49 VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASL-NIQLTCNILT 107
+ K + + ++ Y ++ T + + ++ + T
Sbjct 593 IDAPKNLRVGSRTPASLELTWDNSEAEAHSYRVVYSTLAGEHYHEVLVPRDTGPTTRATL 652
Query 108 FGQLEQNVYGITIIS------GLP--------PEKPKNLSCIVNEGKKMRCEWDG--GRE 151
+ YGI I + +P + P++L + + W G
Sbjct 653 ADLVPGTEYGIGISAVMDSQQSVPATMNARTELDSPRDLLVTASTETSISLSWTKAMGPI 712
Query 152 THLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDH 211
H FT S A+ T ++ + + AE G+ S
Sbjct 713 DHYRVTFTPASGMASE--VTVSRNESQLTLSELEPG----TEYTISIIAER--GRQQSLE 764
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQ 271
D V+P + S+ SS + +TW++PS + ++ + Y +D Q
Sbjct 765 ATVDAFTGVRP----ITQLHFSQLTSSSVNITWSDPSPPADRLV---LTYSPRDEEAPQQ 817
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
+ TR ++ L+P TEY+ + + G S SE +G AP
Sbjct 818 LA---LDGTRRHASLTGLRPSTEYLVSLVAV----HGAVS--SEPVTGSITTG--MDAPK 866
Query 332 FWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--RWKSHLQNYTVNATKLTV 389
+ + ++ + W Y ++ ++ +AT+ +
Sbjct 867 DLRVGNITQD----SMVIYWSPPVAPFD-----HYRISYRAAEGRTDSTAIGNDATEYIM 917
Query 390 NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES 449
L + V+++ G+ ++ V +I P+ ++W P
Sbjct 918 RLLQPATKYEIGVKSVRGREESEVASITTYT-AMDAPLGVTATNITPTEALLQWNPPLMD 976
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES 509
V+ Y+L + + + QE Y NL S Y + + S
Sbjct 977 VESYVLVLTRHTGETILVDGINQE-------YQLTNLQPSTTYTVAMYATNGPLTSQTIS 1029
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
PP+ + +V + A+L W G I NY + YR+ G+ +
Sbjct 1030 TNFTTLLDPPT---NLTASEVTRRSALLSWVPP-----VGDIENYILTYRSTDGSRKELI 1081
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
VD+ T L L+ T Y VR+ A + TFTT
Sbjct 1082 VDAEDTWIRLEGLSETTQYTVRLQAAQNAMRSGFISTTFTT 1122
Score = 139 bits (349), Expect = 4e-32, Method: Composition-based stats.
Identities = 87/490 (18%), Positives = 161/490 (33%), Gaps = 53/490 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGR--ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
+ P + EW R + + L + + +
Sbjct 504 DGPTQILVRDVSDTVAFVEWTPPRARVDAILLKYGLADGEGGRTTFRLQPPLSQYSLQAL 563
Query 185 DYSTVYFVNIEVWVEAENAL-GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
Y + A +AL G S ++ + P NL V + + L+LT
Sbjct 564 RPGARYHL-------AVSALRGANESQPALAQFTTEI--DAPKNLRVGSR--TPASLELT 612
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
W N ++ Y + Y T + ++ + T+ DL P TEY I +
Sbjct 613 WDNSEAEAH---SYRVVYSTLAGEHYHEVLVPRDTGPTTRATLADLVPGTEYGIGISAVM 669
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
+ S+++ T R + + + ++ L W G I
Sbjct 670 D---------SQQSVPATMNAR--TELDSPRDLLVTAST-ETSISLSWTKAM-----GPI 712
Query 364 LDYEVTLTRWKSHLQNYTV--NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
Y VT T TV N ++LT++ T+++ G+ + L F
Sbjct 713 DHYRVTFTPASGMASEVTVSRNESQLTLSELEPGTEYTISIIAERGRQQS--LEATVDAF 770
Query 422 QATHPVMDLK-AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
P+ L + + + + W+ P + +L + ++AP DGT
Sbjct 771 TGVRPITQLHFSQLTSSSVNITWSDPSPPADRLVLTYSPRDEEAPQQL---ALDGTRRHA 827
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
L G L S YL+++ V+ P + P +R + ++ V+ W
Sbjct 828 SLTG-LRPSTEYLVSLVAVHGAVSSEPVTGSITTGMDAPK---DLRVGNITQDSMVIYWS 883
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
+Y I YR G + + + TEY + L T Y + + + G
Sbjct 884 PPVAPFD-----HYRISYRAAEGRTDSTAIGNDATEYIMRLLQPATKYEIGVKSV--RGR 936
Query 601 KDGPEFTFTT 610
++ + TT
Sbjct 937 EESEVASITT 946
Score = 127 bits (318), Expect = 2e-28, Method: Composition-based stats.
Identities = 76/484 (16%), Positives = 143/484 (30%), Gaps = 44/484 (9%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
P+NL + WD T + + + A + + + S
Sbjct 326 APPENLRVTGISDGSIELAWD---SLGAATEYVVSYQPAGPGGSQLQQRVPGDWSTITIT 382
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V V + A + V S + + P L E + +++ W
Sbjct 383 ELEPGVAYNVSIYAV--ISDVLSSPVTTKVTTNLAT--PQGLKFKTITE--TTVEVQWEP 436
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
S + I + K+ ST ++F LKP EY + +K+
Sbjct 437 ---FSFPFDGWEISFIPKNNEG---GVIAQLPSTVTTFNQTGLKPGEEYTVTVVALKDQA 490
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
+ S+ S + P+ D S T + W P + +L Y
Sbjct 491 RSP--PASDSISTL------IDGPTQILVRDVSDTVA----FVEWTP-PRARVDAILLKY 537
Query 367 EVTLTRWKSHLQNYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
+ ++ ++ RY ++ +S A+ +
Sbjct 538 GLADGEGGRTTFRLQPPLSQYSLQALRPGARYHLAVSALRGANESQPALAQFTT---EID 594
Query 425 HPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
P L + W Y + + L+ + ++ G R L
Sbjct 595 APKNLRVGSRTPASLELTWDNSEAEAHSYRVVYSTLAGEHYHEVLVPRDTGPTTRATL-A 653
Query 485 NLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
+L Y I ++ V P ++ A + P + + L W
Sbjct 654 DLVPGTEYGIGISAVMDSQQSVPATMNARTELDSPR---DLLVTASTETSISLSW----- 705
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
G I +Y + + G + V V + ++ TLS L T Y + + A + G +
Sbjct 706 TKAMGPIDHYRVTFTPASGMASEVTVSRNESQLTLSELEPGTEYTISIIA--ERGRQQSL 763
Query 605 EFTF 608
E T
Sbjct 764 EATV 767
Score = 78.4 bits (191), Expect = 3e-13, Method: Composition-based stats.
Identities = 34/215 (16%), Positives = 71/215 (33%), Gaps = 14/215 (7%)
Query 418 ACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
D A P +L+ D + + W + + +Y++ + + QQ
Sbjct 319 GQDCSAVAPPENLRVTGISDGSIELAWDS-LGAATEYVVSYQPAGPGGSQL---QQRVPG 374
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAV 536
T L Y +++ V +D SP + K A P ++ K + +
Sbjct 375 DWSTITITELEPGVAYNVSIYAVISDVLSSPVTTKVTTNLATPQG---LKFKTITETTVE 431
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV-NVDSSHTEYTLSSLTSDTLYMVRMAAY 595
++W+ + I + + + S+ T + + L Y V + A
Sbjct 432 VQWEPFSFPFD-----GWEISFIPKNNEGGVIAQLPSTVTTFNQTGLKPGEEYTVTVVAL 486
Query 596 TDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFL 630
D+ + +T +I V +AF+
Sbjct 487 KDQARSPPASDSISTLIDGPTQILVRDVSDTVAFV 521
>sp|Q9I7U4|TITIN_DROME Titin OS=Drosophila melanogaster OX=7227
GN=sls PE=1 SV=3
Length=18141
Score = 151 bits (381), Expect = 1e-35, Method: Composition-based stats.
Identities = 109/632 (17%), Positives = 191/632 (30%), Gaps = 65/632 (10%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTD 93
+ V +L T CV + + + WK N NR A
Sbjct 17480 QDVVSELDKEVTLSCV-------FGGIPEPKVTWKKNGQVFESRSIRYENRVAKYTIEKT 17532
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPE-KPKNLSCIVNEGKKMRCEWDGGRET 152
TC + + + E + K L+ + G
Sbjct 17533 TIETEATYTCVATNEKGSAETSCRLKLQQKPVLEVEDKYLTQKLRTGS--ILTIPATVRG 17590
Query 153 HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF-VNIEVWVEAENALGKVTSDH 211
+ + T E K T T+ T V + + V A N S
Sbjct 17591 YPQPTVTWHKETIEQKTTKSVTIETTETTSTYTVKKVTREQSGKYKVTATN-----ESGT 17645
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWS 270
+ +V P S+ + + L WT P + I KY ++ + W
Sbjct 17646 TYVECTVQVIDKPSRPQSLEIKDIKKDSIVLEWTPPVDDGGLDIEKYTLEKCDVQNNVWM 17705
Query 271 QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
++ + S+ VQ L +Y+FR+ G+ ++ S+ + ++PS
Sbjct 17706 KVSDFNKDIK--SYAVQKLSMNAQYMFRVVAANPIGESEPTE-SDPVTITKKFEKPSPP- 17761
Query 331 SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH------LQNYTVNA 384
+ L W+ + KI++Y V + + TV
Sbjct 17762 ---RGPTTVSGMNDTSFNLAWEP-SETDGGSKIIEYIVEIREETETTYRSVGVTLGTVTN 17817
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAAVLT---IPACDFQATHPVMDLKAFPKDN-MLW 440
+ + N Y + RN VG S+A T + P +L+A + +
Sbjct 17818 IHVEKVVRNKGYFFRIYARNEVGTSEAFETTEKIVLGRKITPPSPPQNLRAPDVTSRSVT 17877
Query 441 VEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT--YLRGNLAESKCYLITVTP 498
++W P + I +CV + T+W + Y NL E Y V+
Sbjct 17878 LDWEVPARNGGSEITGYCVEKRSSTS-TNWTKVITLDAHQLHYTIDNLKEKCEYWFRVSA 17936
Query 499 VYADGPGSPESIKA-------------------YLK----QAPPSKGP-TVRTKKVGKNE 534
G G+P ++ Y + +A PS + + + N
Sbjct 17937 ENEVGLGAPAVTESISLKTHASEFILVVRNCGSYTEFGFLKAVPSPPTGPLEARVLAANA 17996
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYR-TIIGNETAV-NVDSSHTEYTLSSLTSDTLYMVRM 592
+ EW LP + Y I R V V + ++ + L + YM+R+
Sbjct 17997 HIFEWG-LPESDGGAPLLGYHIAIRDMKKTMWIEVGRVPAGVLKFQIRDLQENHEYMIRI 18055
Query 593 AAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVP 624
A + G + E G P
Sbjct 18056 FAKNEIGLSEPLESEEPYKAMTAGHESLPDEP 18087
Score = 101 bits (251), Expect = 3e-20, Method: Composition-based stats.
Identities = 106/605 (18%), Positives = 199/605 (33%), Gaps = 74/605 (12%)
Query 64 YIVWKTNHFTIPKEQYT--IINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITII 121
+ W I Q + T + D + + + + +
Sbjct 17216 EVTWCKKGKPIKPNQKHEVFVEGTVRRLVIHDASDEDAGEISCVAENVTSSTKLCVEELK 17275
Query 122 SGLPP----EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD 177
LPP +K + + N+ + T + T ++ W T K K+KR
Sbjct 17276 --LPPVITSDKDQTIKVKENDDVTFTV-----KYTGVPTP---EACWTTRKVVIPKSKRT 17325
Query 178 TPT--SCTVDYSTVYFVN---IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
PT + + V+ E V+ N +G+ + P P L +++
Sbjct 17326 IPTIDEQSAKLTIKKVVDDDEGEYTVKLVNPVGEAEASLHLVIMRKPTAPGTPQPLEIMH 17385
Query 233 SEELSSILKLTWTNPSI-KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ L W P I++Y ++Y+ W++I +++T+ LK
Sbjct 17386 -----DSITLYWKAPEDDGKSEIIEYILEYQDVKEEKWTEIR----KIKDTTYTISKLKI 17436
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL-- 349
TEYVFR + E G S S + + +KAPS + ++ + V L
Sbjct 17437 DTEYVFRSIAVNEVGPSPPSPLSPPIRLVPKVE--TKAPSVQEPLQDVVSELDKEVTLSC 17494
Query 350 ----------VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT 399
WK NG++ + R+++ + YT+ T + T T
Sbjct 17495 VFGGIPEPKVTWKK------NGQVFESRSI--RYENRVAKYTIEKTTIETEAT-----YT 17541
Query 400 LTVRNLVGKSDAA-VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI---L 455
N G ++ + L + + ++L + +V+ Y +
Sbjct 17542 CVATNEKGSAETSCRLKLQQKPVLEVEDKYLTQKLRTGSILTI-----PATVRGYPQPTV 17596
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
W + + E TY + + VT G E +
Sbjct 17597 TWHKETIEQKTTKSVTIETTETTSTYTVKKVTREQSGKYKVTATNESGTTYVECTVQVID 17656
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV---DS 572
+ PS+ ++ K + K+ VLEW PVD I YT+ + + N + V +
Sbjct 17657 K--PSRPQSLEIKDIKKDSIVLEWTP-PVDDGGLDIEKYTLE-KCDVQNNVWMKVSDFNK 17712
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLT 632
Y + L+ + YM R+ A G + E T + P ++ +
Sbjct 17713 DIKSYAVQKLSMNAQYMFRVVAANPIGESEPTESDPVTITKKFEKPSPPRGPTTVSGMND 17772
Query 633 TLLGV 637
T +
Sbjct 17773 TSFNL 17777
Score = 94.2 bits (232), Expect = 5e-18, Method: Composition-based stats.
Identities = 56/351 (16%), Positives = 101/351 (29%), Gaps = 50/351 (14%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLET--NFTLKSEWATHKFADCKAKRDTPTSC 182
PP P +S W+ + ++ T +
Sbjct 17760 PPRGPTTVS--GMNDTSFNLAWEPSETDGGSKIIEYIVEIREETETTYRSVGVTLGTVTN 17817
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPV---YKVKPNPPHNLSVINSEELSSI 239
V + A N +G + V P+PP NL + S
Sbjct 17818 IHVEKVVRNKGYFFRIYARNEVGTSEAFETTEKIVLGRKITPPSPPQNLRA--PDVTSRS 17875
Query 240 LKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ L W P+ I Y ++ R+ ++ W+++ D + +T+ +LK EY FR
Sbjct 17876 VTLDWEVPARNGGSEITGYCVEKRSSTSTNWTKVITLDA--HQLHYTIDNLKEKCEYWFR 17933
Query 299 IRCMKEDGKGYWSDWSEEASGIT--------------------YEDRPSKAPSFWYKIDP 338
+ E G G +E S T + PS
Sbjct 17934 VSAENEVGLGAP-AVTESISLKTHASEFILVVRNCGSYTEFGFLKAVPSPPTGPLE---- 17988
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ------NYTVNATKLTVNLT 392
+ W LP + +L Y + + K + V ++
Sbjct 17989 ARVLAANAHIFEW-GLPESDGGAPLLGYHIAIRDMKKTMWIEVGRVPAGVLKFQIRDLQE 18047
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATH------PVMDLKAFPKDN 437
N Y+ + +N +G S+ P A H P ++ + +
Sbjct 18048 NHEYMIRIFAKNEIGLSEPLESEEPYKAMTAGHESLPDEPRTEMSSCNTSS 18098
>sp|H2A0L7|FND1_PINMG Fibronectin type III domain-containing protein
1 OS=Margaritifera margaritifera OX=102329 PE=1 SV=1
Length=754
Score = 146 bits (369), Expect = 6e-35, Method: Composition-based stats.
Identities = 81/421 (19%), Positives = 136/421 (32%), Gaps = 29/421 (7%)
Query 83 NRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKM 142
N T +SVT + S L + L P P NL +
Sbjct 314 NFTQASVTDLNPRSFYSIQVAATLCEAIESEGTSTSVKTPDLIPSAPLNLKLEGTKPNAF 373
Query 143 RCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF-VNIEVWVEAE 201
WD TN+T+ +AT + P + +Y + + A
Sbjct 374 AVSWDPPTVKGTLTNYTI---YATEESGKATMVTIDPKLTSYALYNLYEGTMYTIRIAAS 430
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
+ G K P P N+ I++ S + L W P +I Y I Y
Sbjct 431 SDNGMSPKSEPLEVTTDKFIPMAPRNVRAIDNNLTS--VTLEWDAPLPGRGMIRGYRINY 488
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
T D + + ++ D + T T+ +L P TEY F++ GY S T
Sbjct 489 -TLDFTDYEEMLISDPSITT--ATITNLTPATEYYFQVFARTMKRLGYG---SHLIMNKT 542
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
D PS+ S ++I G + +Q+ W+ PP G I+DY + +
Sbjct 543 KMDVPSEPMSVVHRI---MDNGLQRIQVSWQ--PPENTYGPIIDYIIHWGVRGGATRKEF 597
Query 382 VNATKLTVNLTND------RYLATLTVRNLVGKSDAAVLTIPACDFQ----ATHPVMDLK 431
+ T ++ T+D + L +N+VG ++ V
Sbjct 598 L--TPYVLSWTSDFLDDNANHDFKLFAQNVVGIGKPVAFSVKTLPKPQILVPNVRVKRET 655
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
+ L V W +P+ V + + + + + R E+
Sbjct 656 SKNNITSLTVTWGSPKVPVDGFFVLYRKYEGVYSDRWKFIEIPKPNARGTTITVTQENVP 715
Query 492 Y 492
Y
Sbjct 716 Y 716
Score = 125 bits (314), Expect = 3e-28, Method: Composition-based stats.
Identities = 85/520 (16%), Positives = 157/520 (30%), Gaps = 71/520 (14%)
Query 138 EGKKMRCEWDGG-----RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV 192
+ WD T ++ + + ++ C +++
Sbjct 263 NSSNIYVSWDPPYFEGKPLTGENMHYKVYFS-PSDQYGKATGGEFIFRICDANFTQASVT 321
Query 193 N------IEVWV-----EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
+ + V EA + G TS + P+ P NL + + +
Sbjct 322 DLNPRSFYSIQVAATLCEAIESEGTSTSVK-----TPDLIPSAPLNLKLEGT--KPNAFA 374
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
++W P++K + Y I Y T+++ + + +S+ + +L T Y RI
Sbjct 375 VSWDPPTVK-GTLTNYTI-YATEESGKATMVT---IDPKLTSYALYNLYEGTMYTIRIAA 429
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
++G S SE T + P AP ID +V L W P G
Sbjct 430 SSDNGM---SPKSEPLEVTTDKFIPM-APRNVRAID----NNLTSVTLEWDAPLP--GRG 479
Query 362 KILDYEVTLT----RWKSHLQNYTVNATKLTVNLTN-DRYLATLTVRNLVGKSDAAVLTI 416
I Y + T ++ L + T NLT Y + R + + L +
Sbjct 480 MIRGYRINYTLDFTDYEEMLISDPSITTATITNLTPATEYYFQVFARTMKRLGYGSHLIM 539
Query 417 PACDFQATHPVMDLKAFPKDN---MLWVEWTTPR---ESVKKYILEWCVLSDKAPCITDW 470
M + DN + V W P + YI+ W V T
Sbjct 540 NKTKMDVPSEPMSVVHRIMDNGLQRIQVSWQPPENTYGPIIDYIIHWGVRG----GATRK 595
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKV 530
+ V + L ++ + + G G P + P P VR K+
Sbjct 596 EFLTPYVLS-WTSDFLDDNANHDFKLFAQNVVGIGKPVAFSVKTLPKPQILVPNVRVKRE 654
Query 531 GK----NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN-----VDSSHTEYTLSS 581
+ W V + + + YR G + + T++
Sbjct 655 TSKNNITSLTVTWGSPKV-----PVDGFFVLYRKYEGVYSDRWKFIEIPKPNARGTTITV 709
Query 582 LTSDTLYMVRMAAYTDEGGK--DGPEFTFTTPKFAQGEIE 619
+ Y+V + + + F+ P G+ +
Sbjct 710 TQENVPYVVVCKGFKRQKKPTSNLSSQQFSFPGQQVGQQQ 749
Score = 119 bits (299), Expect = 2e-26, Method: Composition-based stats.
Identities = 69/461 (15%), Positives = 137/461 (30%), Gaps = 51/461 (11%)
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS-------QIPPEDTASTRSS 283
++ + SS + ++W P + + N+ Y+ + + + + +
Sbjct 258 SDTVDNSSNIYVSWDPPYFEGKPLTGENMHYKVYFSPSDQYGKATGGEFIFRICDANFTQ 317
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+V DL P + Y ++ + E T P PS + T+
Sbjct 318 ASVTDLNPRSFYSIQVAA-------TLCEAIESEGTSTSVKTPDLIPSAPLNLKLEGTKP 370
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN---ATKLTVNLT-NDRYLAT 399
+ W G + +Y + T T++ + NL Y
Sbjct 371 N-AFAVSWDPP---TVKGTLTNYTIYATEESGKATMVTIDPKLTSYALYNLYEGTMYTIR 426
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTP---RESVKKYIL 455
+ + G S + D +++A + + +EW P R ++ Y +
Sbjct 427 IAASSDNGMSPKSEPLEVTTDKFIPMAPRNVRAIDNNLTSVTLEWDAPLPGRGMIRGYRI 486
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD--GPGSPESIKAY 513
+ + + D ++ + NL + Y V G GS I
Sbjct 487 NYTLDFTDYEEML---ISDPSITTATI-TNLTPATEYYFQVFARTMKRLGYGS-HLIMNK 541
Query 514 LKQAPPSKGPTV--RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD 571
K PS+ +V R G + W P + G I +Y I + G +
Sbjct 542 TKMDVPSEPMSVVHRIMDNGLQRIQVSWQ--PPENTYGPIIDYIIHWGVRGGATRKEFLT 599
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT---PKFAQGEIEAIVVPVCLA 628
+T L + + ++ A G F+ T P+ +
Sbjct 600 PYVLSWTSDFLDDNANHDFKLFAQNVVGIGKPVAFSVKTLPKPQILVPNVRVKRETSKNN 659
Query 629 FLLTTLL---------GVLFCFNKRDLIKKHIWP--NVPDP 658
T+ G + K + + W +P P
Sbjct 660 ITSLTVTWGSPKVPVDGFFVLYRKYEGVYSDRWKFIEIPKP 700
Score = 89.9 bits (221), Expect = 5e-17, Method: Composition-based stats.
Identities = 50/265 (19%), Positives = 86/265 (32%), Gaps = 22/265 (8%)
Query 366 YEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATH 425
Y+ + ++QN+T + + T + L+ + +
Sbjct 190 YKERMKYPSPYIQNFTASPSNFTYTTFENDVDMRLSSMERISSELVKQMVNCPRGPVPPP 249
Query 426 PVMDLKA----FPKDNMLWVEWTTP---RESVKKYILEWCV------LSDKAPCITDWQQ 472
P + + ++V W P + + + + V KA +
Sbjct 250 PPQSVMVQSDTVDNSSNIYVSWDPPYFEGKPLTGENMHYKVYFSPSDQYGKATGGEFIFR 309
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYAD---GPGSPESIKAYLKQAPPSKGPTVRTKK 529
+L Y I V + G+ S+K PS ++ +
Sbjct 310 ICDANFTQASVTDLNPRSFYSIQVAATLCEAIESEGTSTSVK--TPDLIPSAPLNLKLEG 367
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYM 589
N + WD G + NYTI+ G T V +D T Y L +L T+Y
Sbjct 368 TKPNAFAVSWDPP---TVKGTLTNYTIYATEESGKATMVTIDPKLTSYALYNLYEGTMYT 424
Query 590 VRMAAYTDEGGKDGPE-FTFTTPKF 613
+R+AA +D G E TT KF
Sbjct 425 IRIAASSDNGMSPKSEPLEVTTDKF 449
Score = 71.0 bits (172), Expect = 3e-11, Method: Composition-based stats.
Identities = 49/284 (17%), Positives = 88/284 (31%), Gaps = 27/284 (10%)
Query 126 PEKPKNLSCIVNEGKKMRCEWD---GGR--ETHLETNFTL-KSEWATHKFADCKAKRDTP 179
P P+N+ I N + EWD GR N+TL +++ +D T
Sbjct 451 PMAPRNVRAIDNNLTSVTLEWDAPLPGRGMIRGYRINYTLDFTDYEEMLISDPSITTATI 510
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
T+ T V A H+ + P+ P ++ +
Sbjct 511 TNLTPA------TEYYFQVFARTMKRLGYGSHLIMNKTKMDVPSEPMSVVHRIMDNGLQR 564
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
++++W P I+ Y I + + +T + S S F + + F++
Sbjct 565 IQVSWQPPENTYGPIIDYIIHWGVRGGATRKEFLTPYVLSWTSDFLDDNAN----HDFKL 620
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
G G A + +P + ++ + W P
Sbjct 621 FAQNVVGIGK-----PVAFSVKTLPKPQILVPNVRVKRETSKNNITSLTVTW-GSPKVPV 674
Query 360 NGKILDYE----VTLTRWK-SHLQNYTVNATKLTVNLTNDRYLA 398
+G + Y V RWK + T +TV N Y+
Sbjct 675 DGFFVLYRKYEGVYSDRWKFIEIPKPNARGTTITVTQENVPYVV 718
>sp|Q9HCK4|ROBO2_HUMAN Roundabout homolog 2 OS=Homo sapiens OX=9606
GN=ROBO2 PE=1 SV=2
Length=1378
Score = 148 bits (372), Expect = 6e-35, Method: Composition-based stats.
Identities = 116/700 (17%), Positives = 216/700 (31%), Gaps = 126/700 (18%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P + VV C ++ + WK + +P+ +Y I + + T
Sbjct 231 PINQVVLEEEAVEFRCQVQ-------GDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKT 283
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLPPE---KPKNLSCIVNEGKKMRCEWDGG 149
+ G++E + T+ PP+ +P++ C
Sbjct 284 MSTDEGTYMCIAENRVGKMEAS---ATLTVRAPPQFVVRPRDQIVAQGRTVTFPC----- 335
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTS-CTVDYSTVYFVN--------IEVWVEA 200
ET + + + + P S C+V + + + +A
Sbjct 336 -ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYI-CQA 393
Query 201 ENALGKVTSD-HINFDPVYKVKPNP-----PHNLSV--------INSEELSSILKLTWTN 246
G + + + V +P P P N ++ + ++W
Sbjct 394 LTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISW-- 451
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
K+ T+ P T + + +++L+ + G
Sbjct 452 ----------------LKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSG 495
Query 307 KGYWS---DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT-LPPFEANGK 362
+ WS D +E + I+ S P K + +V L W+ P
Sbjct 496 ETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKN-SVTLSWQPGTPGTLPASA 554
Query 363 --ILDYEVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAAVLTIPA 418
I + +++ + N+ V T TV N YL + N G SD + ++ P
Sbjct 555 YIIEAFSQSVSNSWQTVANH-VKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPV 613
Query 419 CDFQATHPVMDL------------------KAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
+ P + + V WT R+ ++I + V+
Sbjct 614 RTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQP--QFIQGYRVM 671
Query 461 SDKAPCI---TDWQQEDGTV--HRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYL 514
+ + + WQ D V R+ + NL + Y I V P + + G ES
Sbjct 672 YRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRT 731
Query 515 KQAPPSKGPT----VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN- 569
+ PS P + + WD P D QNG I+ Y I+ +GNET +
Sbjct 732 TEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIW---CLGNETRFHI 788
Query 570 ---VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE------------------FTF 608
VD++ + L Y V +AA T G E +
Sbjct 789 NKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRRNEVVITENNNSI 848
Query 609 TTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIK 648
T + A + + A + + ++ + +R K
Sbjct 849 TEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRK 888
>sp|Q5ZJP5|FND3A_CHICK Fibronectin type-III domain-containing
protein 3a OS=Gallus gallus OX=9031 GN=FNDC3A PE=2 SV=2
Length=1198
Score = 147 bits (371), Expect = 9e-35, Method: Composition-based stats.
Identities = 86/527 (16%), Positives = 153/527 (29%), Gaps = 62/527 (12%)
Query 126 PEKPKNLSCIVNEGK----KMRCEWDGGRETH---LETNFTLKSEWATHKFADCKAKRDT 178
P+KP S +GK + WD ++ + T SE + D
Sbjct 562 PDKPGAPSKPSVKGKIHAQSFKIIWDPPKDNGGAAINTYVVEISEGSNGNKWDTIYSGAA 621
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
+ + + V G+ + V P P + +
Sbjct 622 REHLCDRLNPG--CSYRLRVYCIGEGGQSMASDSLLVQTPAVVPGPCQPPRLQGRP-RAR 678
Query 239 ILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
++L W P I Y ++ + ++ + TV L P Y F
Sbjct 679 EIQLRWGPPQVDGGSPITCYGLEMFQTETDEHREVYQ----GSDVECTVGSLLPGRMYNF 734
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPS--KAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
R+R + G G +S+ E T P K P + + W+
Sbjct 735 RLRAANKAGFGPYSEKCE---ITTAPGPPDQCKPPQVTCRSAACAQ-------VSWEVP- 783
Query 356 PFEANGK-ILDYEVTLTRWKSHLQNY---TVNATKLTVNLTNDRYLATLTVRNLVGKSDA 411
+NG + +Y + + +Q ++ L Y + N+ G
Sbjct 784 --VSNGADVTEYRLEWGGMEGCMQISYCGPGLNCEMKGLLPATIYYCRVQAVNVAGAGPF 841
Query 412 AVLTIPACDFQATHPVMDLKAFPKD----------NMLWVEWTTP---RESVKKYILEWC 458
+ + V L+ +D L + W P + Y ++
Sbjct 842 SEVVACMTPASVPAVVTCLRGLSEDEVESPHYYPSTCLALSWEKPCDHGSEITGYSID-- 899
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQA 517
D Q +Y L Y I + + + G G +IK K
Sbjct 900 --------FGDKQPITVGKVLSYFIDGLQPDTTYRIRIQALNSLGAGPFSHTIKLKTKPL 951
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY 577
PP P + L+W + I+ Y + G ++ Y
Sbjct 952 PPD-PPRLECVAYSSQTLKLKWGEGTAKALTDSIQ-YHLQMEDKNGRFVSL-YRGPCHTY 1008
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVV 623
+ L+ T Y + A + G E+ FTTPK ++A +
Sbjct 1009 KVQRLSESTSYKFCIQACNEAGEGPLSQEYVFTTPKSVPAALKAPRI 1055
Score = 144 bits (362), Expect = 1e-33, Method: Composition-based stats.
Identities = 81/491 (16%), Positives = 143/491 (29%), Gaps = 38/491 (8%)
Query 141 KMRCEWDGGRE--------THLETNFTLKS-EWATHKFADCKAKRDTPTSCTVDYSTVYF 191
W T++ +T + T K K +
Sbjct 282 TALLMWSPPSIDVGEDTDKTNIPGVYTYEVMISNTGKDGKYKTVYIGEENKVTVNDLRPA 341
Query 192 VNIEVWVEAE-NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+ V+ E N + S+ +F + +P+ P+ + N + S L L W
Sbjct 342 TDYHAKVQVECNCVKGSPSEVESFTTMSC-EPDAPNLPRITNRTKNS--LTLQWKASCDN 398
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
I Y +++ D + + + + + L P Y FR+ + G +
Sbjct 399 GSKIHSYLLEW---DEGKGNGEFCQCYYGQQKQYRITKLSPAMGYTFRLAAKNDMGMSGF 455
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S+ E + + A + + L W ++ I Y + +
Sbjct 456 SE--EVLYHTSGTAATTPASPLLINAGVTW------LSLQWTKPSGTPSDEGI-SYILEM 506
Query 371 TRWKSH----LQNYTVNATKLTVNLTN-DRYLATLTVRNLVGKS-DAAVLTIPACDFQAT 424
S + + T NL +Y + N GKS + + C +
Sbjct 507 EDENSGYGFKPKYDGDDLTYTVKNLRRSTKYKFRVIAYNSEGKSSPSETVDYTTCPDKPG 566
Query 425 HPVM-DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
P +K + W P+++ I + V + W R +L
Sbjct 567 APSKPSVKGKIHAQSFKIIWDPPKDNGGAAINTYVVEISEGSNGNKWDTIYSGAAREHLC 626
Query 484 GNLAESKCYLITVTPVYADGPGS--PESIKAYLKQAPPSKGPTVRTK-KVGKNEAVLEWD 540
L Y + V +G S +S+ P R + + E L W
Sbjct 627 DRLNPGCSYRLRVY-CIGEGGQSMASDSLLVQTPAVVPGPCQPPRLQGRPRAREIQLRWG 685
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
VD I Y + +E S E T+ SL +Y R+ A G
Sbjct 686 PPQVD-GGSPITCYGLEMFQTETDEHREVYQGSDVECTVGSLLPGRMYNFRLRAANKAGF 744
Query 601 KDGPEF-TFTT 610
E TT
Sbjct 745 GPYSEKCEITT 755
Score = 119 bits (299), Expect = 4e-26, Method: Composition-based stats.
Identities = 75/573 (13%), Positives = 168/573 (29%), Gaps = 51/573 (9%)
Query 51 KEKCMDYFHVNANYIVWK---------TNHFTIPKEQ------YTIINRTASSVTFTDIA 95
K H + I+W N + + + + I A+ D
Sbjct 570 KPSVKGKIHAQSFKIIWDPPKDNGGAAINTYVVEISEGSNGNKWDTIYSGAAREHLCDRL 629
Query 96 SLNIQLTCNILTFGQLEQNVYGITIISGLP-----PEKPKNLSCIVNEGKKMRCEWDGGR 150
+ + G+ Q++ +++ P P +P L ++++ W +
Sbjct 630 NPGCSYRLRVYCIGEGGQSMASDSLLVQTPAVVPGPCQPPRLQ-GRPRAREIQLRWGPPQ 688
Query 151 ETH--LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
T + L+ + T + + + CTV + + A N G
Sbjct 689 VDGGSPITCYGLE-MFQTETDEHREVYQGSDVECTVGSLLPGRM-YNFRLRAANKAGFGP 746
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST 268
P+ V ++ +++W P + +Y ++
Sbjct 747 YSEKCEITTAPGPPDQCKPPQVTCR--SAACAQVSWEVPVSNGADVTEYRLE-----WGG 799
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS- 327
+ ++ L P T Y R++ + G G + SE + +T P+
Sbjct 800 MEGCMQISYCGPGLNCEMKGLLPATIYYCRVQAVNVAGAGPF---SEVVACMTPASVPAV 856
Query 328 ----KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN 383
+ S P + + L W+ P + +I Y + K + V
Sbjct 857 VTCLRGLSEDEVESPHYYPSTC-LALSWEK--PCDHGSEITGYSIDFGD-KQPITVGKVL 912
Query 384 ATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDLKAFPKDNMLWVE 442
+ + + Y + N +G + + + P ++ A+ L ++
Sbjct 913 SYFIDGLQPDTTYRIRIQALNSLGAGPFSHTIKLKTKPLPPDPPRLECVAYSSQT-LKLK 971
Query 443 WTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD 502
W +++ + + TY L+ES Y +
Sbjct 972 WGEGTAKALTDSIQYHLQMEDKNGRFVSLYRGPC--HTYKVQRLSESTSYKFCIQACNEA 1029
Query 503 GPGSPESIKAYL-KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI 561
G G + ++ P+ R +++ + + W+ L + I Y +
Sbjct 1030 GEGPLSQEYVFTTPKSVPAALKAPRIERINDHTCEITWEVLQPMKGDPVI--YCLQVMVG 1087
Query 562 IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
+E + + L + Y R A
Sbjct 1088 KDSEFKQIYKGPDWSFRYTGLQLNCEYRFRACA 1120
>sp|P11276|FINC_MOUSE Fibronectin OS=Mus musculus OX=10090 GN=Fn1
PE=1 SV=4
Length=2477
Score = 147 bits (371), Expect = 1e-34, Method: Composition-based stats.
Identities = 119/748 (16%), Positives = 216/748 (29%), Gaps = 69/748 (9%)
Query 60 VNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGIT 119
A I +K + + S + ++ T I ++ I
Sbjct 1107 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYTYTIQVLRDGQERDAPIV 1166
Query 120 IISGLPPEKPKNLSCIVN-EGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDT 178
P P NL N + + W+ + T + + T + +
Sbjct 1167 NRVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI-TGYRI-----TTTPTNGQQGTSL 1220
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
D S+ F N+ +E ++ V D + V P P + + S
Sbjct 1221 EEVVHADQSSCTFENLNPGLEYNVSVYTVKDDKESAPISDTVVPEVPQLTDLSFVDITDS 1280
Query 239 ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ L WT + S I+ Y I I + S+ +TV L+P +Y
Sbjct 1281 SIGLRWTP--LNSSTIIGYRITVVAAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDYDIS 1336
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+ + G E++ T + + P + G T+++ W P E
Sbjct 1337 VITLINGG---------ESAPTTLTQQTAVPPPTDLRFT---NIGPDTMRVTWAPPPSIE 1384
Query 359 ANGKILDYE-VTLTRWKSHLQNYT-VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
++ Y V + L NA LT L YL +++ V + ++
Sbjct 1385 LTNLLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYLVSVS---SVYEQHESIPLR 1441
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
P + N V W PR + YI+ D + +
Sbjct 1442 GRQKTGLDSPTGFDSSDITANSFTVHWVAPRAPITGYIIRHHAEHSVGRPRQD--RVPPS 1499
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEA 535
+ NL Y++++ V P +QA S P +
Sbjct 1500 RNS-ITLTNLNPGTEYVVSIIAVNGREESPP----LIGQQATVSDIPRDLEVIASTPTSL 1554
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
++ W+ V +R Y I Y GN V S + T++++ Y + +
Sbjct 1555 LISWEPPAVS-----VRYYRITYGETGGNSPVQEFTVPGSKSTATINNIKPGADYTITLY 1609
Query 594 AYTDEGGKDGPE--------------FTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLF 639
A T G I +P +
Sbjct 1610 AVTGRGDSPASSKPVSINYKTEIDKPSQMQVTDVQDNSISVRWLPSTSPVTGYRVTTT-- 1667
Query 640 CFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEAN 699
K L PD ++ I P + ++++ +V I +
Sbjct 1668 --PKNGLGPSKTKTASPDQTEMTIEGLQPTVEYVVSVYAQNRNGESQPLVQTAVTNI--D 1723
Query 700 DKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQY 759
K +D K + +G S ++ S P + + T +
Sbjct 1724 RPKGLAFTDVDVDSIKIAWESPQGQVS----RYRVTYSSPEDGIRELFPAPDGEDDTAEL 1779
Query 760 STVVHSGYRHQVPSVQVFSRSESTQPLL 787
+ G + V V + ES QPL+
Sbjct 1780 -QGLRPGSEYTVSVVALHDDMES-QPLI 1805
Score = 126 bits (316), Expect = 4e-28, Method: Composition-based stats.
Identities = 68/477 (14%), Positives = 141/477 (30%), Gaps = 50/477 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P NL + + + W R T T + S
Sbjct 997 DAPTNLQFVNETDRTVLVTWTPPRARIAGYRLT---AGLTRGGQPKQYNVGPLASKYPLR 1053
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ V + A + F + ++ PP+N +E + + +TWT
Sbjct 1054 NLQPGSEYTVTLVAVKGNQQSPKATGVFTTLQPLRSIPPYN-----TEVTETTIVITWTP 1108
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ + + R P + S S V L P EY + I+ +++
Sbjct 1109 -----APRIGFKLGVRPSQGGE----APREVTSDSGSIVVSGLTPGVEYTYTIQVLRD-- 1157
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
G D +T P+ + + + W+ + I Y
Sbjct 1158 -GQERDAPIVNRVVTPLSPPT-------NLHLEANPDTGVLTVSWERSTTPD----ITGY 1205
Query 367 EVTLTRWKSHLQNYTV-----NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+T T + + T N ++V + ++A ++
Sbjct 1206 RITTTPTNGQQGTSLEEVVHADQSSCTFENLNPGLEYNVSVYTVKDDKESAPISDTVVPE 1265
Query 422 QATHPVMDLKAFPKDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ D+ + + WT ++ Y + + P D+
Sbjct 1266 VPQLTDLSFVDI-TDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSS---VGY 1321
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
Y L Y I+V + G +P ++ +Q +R +G + + W
Sbjct 1322 YTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAVPPPTDLRFTNIGPDTMRVTWA 1378
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNET--AVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
P + N + Y + E +++ S L++L T Y+V +++
Sbjct 1379 PPPSIE----LTNLLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYLVSVSSV 1431
Score = 124 bits (312), Expect = 1e-27, Method: Composition-based stats.
Identities = 73/576 (13%), Positives = 169/576 (29%), Gaps = 64/576 (11%)
Query 80 TIINRTASSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNE 138
+ + +S+T T++ ++ + + + G + P++L I +
Sbjct 1494 DRVPPSRNSITLTNLNPGTEYVVSIIAVNGREESPPLIGQQATVS---DIPRDLEVIAST 1550
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
+ W+ + T + S + + + +
Sbjct 1551 PTSLLISWEPPAVSVRYYRIT--YGETGGNSPVQEFTVPGSKSTATINNIKPGADYTITL 1608
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A G + YK + + P + V + ++ S + + W + + Y
Sbjct 1609 YAVTGRGDSPASSKPVSINYKTEIDKPSQMQVTDVQDNS--ISVRWLP---STSPVTGYR 1663
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA- 317
+ K+ S+ + ++ T++ L+P EYV + +G+ S+
Sbjct 1664 VTTTPKNGLGPSKTKT--ASPDQTEMTIEGLQPTVEYVVSVYAQNRNGE------SQPLV 1715
Query 318 -SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
+ +T DRP +D ++++ W+ G++ Y VT + +
Sbjct 1716 QTAVTNIDRPKGLAFTDVDVD--------SIKIAWE-----SPQGQVSRYRVTYSSPEDG 1762
Query 377 LQNYT------VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
++ + +L Y ++ + +S + A +L
Sbjct 1763 IRELFPAPDGEDDTAELQGLRPGSEYTVSVVALHDDMESQP----LIGIQSTAIPAPTNL 1818
Query 431 K-AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
K + +W P + Y + V + + + L +
Sbjct 1819 KFSQVTPTSFTAQWIAPSVQLTGYRV--RVNPKEKTGPMKEINLSPDS-SSVIVSGLMVA 1875
Query 490 KCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y ++V + P + S R + + W +
Sbjct 1876 TKYEVSVYALKDTLTSRPAQGVITTLENV-SPPRRARVTDATETTITISWR-TKTET--- 1930
Query 550 FIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
I + + ++ YT++ L T Y + + D
Sbjct 1931 -ITGFQVDAIPANGQTPVQRSISPDVRSYTITGLQPGTDYKIHLYTLND--------NAR 1981
Query 609 TTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
++P AI P L FL TT +L +
Sbjct 1982 SSPVIIDAS-TAIDAPSNLRFLTTTPNSLLVSWQAP 2016
Score = 121 bits (304), Expect = 1e-26, Method: Composition-based stats.
Identities = 70/476 (15%), Positives = 141/476 (30%), Gaps = 51/476 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+KP + + + W T + A D
Sbjct 1633 DKPSQMQVTDVQDNSISVRWLPSTSPVTGYRVTTTPKNGLGPSKTKTASPDQTEMTIEGL 1692
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V V V A+N G+ + +P + ++ +K+ W +
Sbjct 1693 QPT--VEYVVSVYAQNRNGESQ-PLVQTAVTNIDRPK-----GLAFTDVDVDSIKIAWES 1744
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P + +Y + Y + + P D +Q L+P +EY + + +D
Sbjct 1745 PQ---GQVSRYRVTYSSPEDGIRELFPAPDGEDDT--AELQGLRPGSEYTVSVVALHDDM 1799
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
+ S+ GI P+ + ++ P+ + W ++ Y
Sbjct 1800 E------SQPLIGIQSTAIPAPTNLKFSQVTPT------SFTAQWIAPSV-----QLTGY 1842
Query 367 EVTLTRWKSHLQNYTVNATK------LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
V + + +N + ++ + +Y ++ S A I +
Sbjct 1843 RVRVNPKEKTGPMKEINLSPDSSSVIVSGLMVATKYEVSVYALKDTLTSRPAQGVITTLE 1902
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ + + + + W T E++ + ++ + + P Q+ R+
Sbjct 1903 NVSPPRRARVTD-ATETTITISWRTKTETITGFQVDAIPANGQTP----VQRSISPDVRS 1957
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
Y L Y I + + + SP I A PS +R N ++ W
Sbjct 1958 YTITGLQPGTDYKIHLYTLNDNARSSPVIIDASTAIDAPS---NLRFLTTTPNSLLVSWQ 2014
Query 541 QLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
I Y I Y E TE T++ L T Y + + A
Sbjct 2015 -----APRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2065
Score = 118 bits (295), Expect = 1e-25, Method: Composition-based stats.
Identities = 74/480 (15%), Positives = 138/480 (29%), Gaps = 59/480 (12%)
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
K W ++T+K + Y +
Sbjct 647 PKTSTGRWKEATIPGHLNSYTIKGLTPGVIYE-------GQLISIQQYGHREVTRFDFTT 699
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS-EELSSILKLTWTNPSIKSVIILKY 257
A + T + P P + + E +S ++W + S + +
Sbjct 700 SASTPVTSNT-------VTGETAPYSPVVATSESVTEITASSFVVSWVSASDT---VSGF 749
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
++Y + Q D ST +S + DL P +Y+ + + E+GK
Sbjct 750 RVEYELSEEGDEPQY--LDLPSTATSVNIPDLLPGRKYIVNVYQISEEGKQSL------I 801
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL 377
+ P P ++ + W I Y + +
Sbjct 802 LSTSQTTAPDAPPDPTV-----DQVDDTSIVVRW-----SRPQAPITGYRIVYSPSVEGS 851
Query 378 QNY-----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA---THPVMD 429
T N+ L+ +Y T+ +S + P D
Sbjct 852 STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVFIQQETTGTPRSDNVPPPTD 911
Query 430 LKAFPKDNM-LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
L+ ++ + + WT P V Y +E VL P Q+ + L+
Sbjct 912 LQFVELTDVKVTIMWTPPDSVVSGYRVE--VLPVSLPGEHG-QRLPVNRNTFAEITGLSP 968
Query 489 SKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
YL V V+ +P + + K P+ ++ ++ W
Sbjct 969 GVTYLFKVFAVHQGRESNPLTAQQTTKLDAPT---NLQFVNETDRTVLVTWTPPRAR--- 1022
Query 549 GFIRNYTIFYR-TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
I Y + T G NV ++Y L +L + Y V + A +G + P+ T
Sbjct 1023 --IAGYRLTAGLTRGGQPKQYNVGPLASKYPLRNLQPGSEYTVTLVAV--KGNQQSPKAT 1078
Score = 114 bits (285), Expect = 2e-24, Method: Composition-based stats.
Identities = 46/384 (12%), Positives = 123/384 (32%), Gaps = 28/384 (7%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + + + + + W P I KY +++R K ++ + +S+
Sbjct 611 PVQVIITETPSQPNSHPIQWNAPEPSH--ITKYILRWRPKTSTG--RWKEATIPGHLNSY 666
Query 285 TVQDLKPFTEYVFRIRCMKEDGKG------YWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
T++ L P Y ++ +++ G + + S + T + +
Sbjct 667 TIKGLTPGVIYEGQLISIQQYGHREVTRFDFTTSASTPVTSNTVTGETAPYSPVVATSES 726
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLA 398
+ + W + + G ++YE++ + + AT + +
Sbjct 727 VTEITASSFVVSWVSASDTVS-GFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 785
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWC 458
+ V + + +++ + P D + V W+ P+ + Y + +
Sbjct 786 IVNVYQISEEGKQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY- 844
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
S + T + L +L Y IT+ V + +P I+ P
Sbjct 845 --SPSVEGSSTELNLPETANSVTL-SDLQPGVQYNITIYAVEENQESTPVFIQQETTGTP 901
Query 519 ----PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI---IGNETAVNVD 571
++ ++ + + W + + Y + + + + V+
Sbjct 902 RSDNVPPPTDLQFVELTDVKVTIMWTPP-----DSVVSGYRVEVLPVSLPGEHGQRLPVN 956
Query 572 SSHTEYTLSSLTSDTLYMVRMAAY 595
+ ++ L+ Y+ ++ A
Sbjct 957 RNTFAE-ITGLSPGVTYLFKVFAV 979
Score = 90.3 bits (222), Expect = 7e-17, Method: Composition-based stats.
Identities = 62/397 (16%), Positives = 112/397 (28%), Gaps = 39/397 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
++PK L+ + ++ W+ + + + + D
Sbjct 1723 DRPKGLAFTDVDVDSIKIAWE--SPQGQVSRYRVTYSSPEDGIRELFPAPDGEDDTAELQ 1780
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V V A + + S + P P NL S+ + W
Sbjct 1781 GLRPGSEYTVSVVALHD--DMESQPL-IGIQSTAIP-APTNLK--FSQVTPTSFTAQWIA 1834
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
PS V + Y ++ K+ + + + SS V L T+Y + +K+
Sbjct 1835 PS---VQLTGYRVRVNPKEKTGPM--KEINLSPDSSSVIVSGLMVATKYEVSVYALKDTL 1889
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
S A G+ P D + T T+ + W+T I +
Sbjct 1890 T------SRPAQGVITTLENVSPPRRARVTDATET----TITISWRTKTET-----ITGF 1934
Query 367 EVTLTRWKSHLQNY-----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+V V + +T Y L N +S ++
Sbjct 1935 QVDAIPANGQTPVQRSISPDVRSYTITGLQPGTDYKIHLYTLNDNARSSPVIIDASTAI- 1993
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
P N L V W PR + YI+++ +P + V
Sbjct 1994 --DAPSNLRFLTTTPNSLLVSWQAPRARITGYIIKYE--KPGSPPREVVPRPRPGVTEAT 2049
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ G L Y I V + + P + + P
Sbjct 2050 ITG-LEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2085
Score = 59.1 bits (141), Expect = 2e-07, Method: Composition-based stats.
Identities = 53/333 (16%), Positives = 108/333 (32%), Gaps = 36/333 (11%)
Query 501 ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G + ++ Y P + + N ++W+ I Y + +R
Sbjct 593 GIGEWHCQPLQTYPGTTGPVQVI-ITETPSQPNSHPIQWNAPEPSH----ITKYILRWRP 647
Query 561 II--GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT-------- 610
G + YT+ LT +Y ++ + G ++ F FTT
Sbjct 648 KTSTGRWKEATIPGHLNSYTIKGLTPGVIYEGQLISIQQYGHREVTRFDFTTSASTPVTS 707
Query 611 -----------PKFAQGE-IEAIVVPVCLAFLLT---TLLGVLFCFNKRDLIKKHIWPNV 655
P A E + I + ++ T+ G + + + + ++
Sbjct 708 NTVTGETAPYSPVVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 767
Query 656 PDPSKS-HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPF---PEDLKSL 711
P + S +I P N + S P +D +
Sbjct 768 PSTATSVNIPDLLPGRKYIVNVYQISEEGKQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 827
Query 712 DLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQV 771
+ + + G+ S SS+ ++ + + + + VQY+ +++ +Q
Sbjct 828 VRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 887
Query 772 PSVQVFSRSEST-QPLLDSEERPEDLQLVDHVD 803
+ VF + E+T P D+ P DLQ V+ D
Sbjct 888 STP-VFIQQETTGTPRSDNVPPPTDLQFVELTD 919
>sp|Q0E9H9|DSCA1_DROME Cell adhesion molecule Dscam1 OS=Drosophila
melanogaster OX=7227 GN=Dscam1 PE=1 SV=1
Length=2016
Score = 147 bits (370), Expect = 2e-34, Method: Composition-based stats.
Identities = 105/651 (16%), Positives = 204/651 (31%), Gaps = 94/651 (14%)
Query 40 LHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPK-EQYTIINRTASSVTFTDIASLN 98
+ +A CV+ + + I W N I E + R + +I SLN
Sbjct 632 VGDIASANCVVPKGDL------PLEIRWSLNSAPIVNGENGFTLVRLNKRTSLLNIDSLN 685
Query 99 IQLTCNILTF--GQLEQNVYGITIISGLPPE---KPKNLSCIVNEGKKMRC--------- 144
+ Y + +PP +P + + K+ C
Sbjct 686 AFHRGVYKCIATNPAGTSEYVAELQVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQ 745
Query 145 -EWD------GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
W G L+ + ++ E T + + + C
Sbjct 746 VTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLC--------------- 790
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI---LKLTWTNPSIKSVII 254
EA N +G S I P + + + L K + I
Sbjct 791 -EAINGIGSGLSAVIMISVQ------APPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGI 843
Query 255 L--KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
L N++ K+ + ++ + SS +++ + +F G
Sbjct 844 LWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFG------ 897
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR 372
S++AS + P +D + R+VQL W P++ N + Y + R
Sbjct 898 -SDDASINMIVQEVPEMPYALKVLD----KSGRSVQLSW--AQPYDGNSPLDRYIIEFKR 950
Query 373 WKSHLQNY-----TVNATKLTVNLTNDR--YLATLTVRNLVGKSDAA-VLTIPACDFQAT 424
++ + T+ V + Y + N +G S ++ +TI + +
Sbjct 951 SRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPS 1010
Query 425 HPVMDLKAFPKD-NMLWVEWTTPR-----ESVKKYILEWCVLSDKAPCITDWQQ--EDGT 476
++K P + + V W P + Y + + + + + + + +
Sbjct 1011 GKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEG 1070
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPT-VRTKKVGKNE 534
NL Y + + G G E K + + PS+ P+ +
Sbjct 1071 KEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQT 1130
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIG--NETAVNVDSSHTEYT-LSSLTSDTLYMVR 591
+ W P++ NG I+ Y + Y +ET + + + T L L T Y ++
Sbjct 1131 IRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQ 1190
Query 592 MAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFN 642
+ A T G DG + P Q E + P + L+ +L +
Sbjct 1191 VLATTAGG--DGVR---SVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWR 1236
Score = 120 bits (300), Expect = 3e-26, Method: Composition-based stats.
Identities = 85/518 (16%), Positives = 161/518 (31%), Gaps = 54/518 (10%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEW-DGGRETHLETNFTLKSEWA-THKFADCKAKRDTPT 180
G P + P + +C + +R W E+ T K +A + ++ D + T
Sbjct 1112 GTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKT 1171
Query 181 SCT--VDYSTVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
+ + V + + N + V A A G V S I+ V P P ++ + +
Sbjct 1172 ASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDV-PEAPTDVKALVMG--N 1228
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ + ++W P+ + II +Y + + + A T + + + SF +L+ Y F
Sbjct 1229 AAILVSWRPPAQPNGIITQYTVYSKAEGAET--ETKTQKVPHYQMSFEATELEKNKPYEF 1286
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID---------PSHTQGYRTVQ 348
+ G+G S + + P+K SF P G +
Sbjct 1287 WVTASTTIGEGQQSK---SIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPE 1343
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLV 406
+ WK + + ++ + + L + N D + N +
Sbjct 1344 ITWK---------------IKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSI 1388
Query 407 GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
K I Q+ H + + + Y L + P
Sbjct 1389 AKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYK------PE 1442
Query 467 ITDWQQEDGTVHRTY-LRGNLAESKCYLITVTPVYADGPGSPESI-KAYLKQAPPSKGPT 524
+W+ + +V L Y + T G G I K P
Sbjct 1443 FGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEK 1502
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGF-IRNYTIFYRTIIG-NETAVNVDSS-HTEYTLSS 581
R +V N L G + ++ + + ++ + Y +
Sbjct 1503 PRFIEVSSNSVSL---HFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLD 1559
Query 582 LTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE 619
L T Y +R+ A+ G E+ F T G I
Sbjct 1560 LEPATWYNLRITAHNSAGFTV-AEYDFATLTVTGGTIA 1596
>sp|P04937|FINC_RAT Fibronectin OS=Rattus norvegicus OX=10116
GN=Fn1 PE=1 SV=2
Length=2477
Score = 146 bits (367), Expect = 4e-34, Method: Composition-based stats.
Identities = 90/557 (16%), Positives = 159/557 (29%), Gaps = 43/557 (8%)
Query 60 VNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGIT 119
A I +K + + S + ++ T I ++ I
Sbjct 1107 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYTYTIQVLRDGQERDAPIV 1166
Query 120 IISGLPPEKPKNLSCIVN-EGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRD 177
P P NL N + + W+ + T A +
Sbjct 1167 NRVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGTALEEVVHA 1226
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
+SCT +E V S I+ V P P + +
Sbjct 1227 DQSSCTF---ENRNPGLEYNVSVYTVKDDKESAPIS----DTVIPEVPQLTDLSFVDITD 1279
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
S + L WT + S I+ Y I I + S+ +TV L+P +Y
Sbjct 1280 SSIGLRWTP--LNSSTIIGYRITVVAAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDYDI 1335
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
+ + G E++ T + + P + G T+++ W P
Sbjct 1336 SVITLINGG---------ESAPTTLTQQTAVPPPTDLRFT---NIGPDTMRVTWAPPPSI 1383
Query 358 EANGKILDYE-VTLTRWKSHLQNYT-VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT 415
E ++ Y V + L NA LT L YL +++ V + ++
Sbjct 1384 ELTNLLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYLVSVS---SVYEQHESIPL 1440
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
P + N V W PR + YI+ D +
Sbjct 1441 RGRQKTGLDSPTGFDSSDVTANSFTVHWVAPRAPITGYIIRHHAEHSAGRPRQD--RVPP 1498
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
+ + NL Y++T+ V P + + +
Sbjct 1499 SRNS-ITLTNLNPGTEYIVTIIAVNGREESPPLIGQ---QSTVSDVPRDLEVIASTPTSL 1554
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
++ W+ V +R Y I Y GN V S + T++++ Y + +
Sbjct 1555 LISWEPPAVS-----VRYYRITYGETGGNSPVQEFTVPGSKSTATINNIKPGADYTITLY 1609
Query 594 AYTDEGGKDGPEFTFTT 610
A T G +
Sbjct 1610 AVTGRGDSPASSKPVSI 1626
Score = 136 bits (343), Expect = 3e-31, Method: Composition-based stats.
Identities = 85/539 (16%), Positives = 160/539 (30%), Gaps = 66/539 (12%)
Query 81 IINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPK--NLSCIVNE 138
+++ SS TF + + ++ ++ T +++ I + PE P+ +LS +
Sbjct 1223 VVHADQSSCTFEN-RNPGLEYNVSVYTVKDDKES---APISDTVIPEVPQLTDLSFVDIT 1278
Query 139 GKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
+ W T + T+ + + +I V
Sbjct 1279 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV- 1337
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY 257
+ N S V P P +L N +++TW P S+ +
Sbjct 1338 ITLING---GESAPTTLTQQTAVPP--PTDLRFTNIG--PDTMRVTWAPP--PSIELTNL 1388
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
++Y + + + ++ + +L P TEY+ + + E + S
Sbjct 1389 LVRYSPVKNE--EDVAELSISPSDNAVVLTNLLPGTEYLVSVSSVYEQHE------SIPL 1440
Query 318 SGI--TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
G T D P+ S + + + W I Y + S
Sbjct 1441 RGRQKTGLDSPTGFDSSDVTAN--------SFTVHW-----VAPRAPITGYIIRHHAEHS 1487
Query 376 HLQNY------TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMD 429
+ + N+ LT Y+ T+ N +S + + P
Sbjct 1488 AGRPRQDRVPPSRNSITLTNLNPGTEYIVTIIAVNGREESPPLIGQQSTV---SDVPRDL 1544
Query 430 LKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
L + W P SV+ Y + + +P + T N+
Sbjct 1545 EVIASTPTSLLISWEPPAVSVRYYRITYGETGGNSPVQ---EFTVPGSKSTATINNIKPG 1601
Query 490 KCYLITVTPVYADGPGS----PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
Y IT+ V G P SI + PS+ + V N + W
Sbjct 1602 ADYTITLYAVTGRGDSPASSKPVSINYQTEIDKPSQM---QVTDVQDNSISVRWLPS--- 1655
Query 546 VQNGFIRNYTIFY--RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ Y + + +G + V TE T+ L Y+V + A G
Sbjct 1656 --TSPVTGYRVTTAPKNGLGPTKSQTVSPDQTEMTIEGLQPTVEYVVSVYAQNRNGESQ 1712
Score = 128 bits (320), Expect = 2e-28, Method: Composition-based stats.
Identities = 81/614 (13%), Positives = 177/614 (29%), Gaps = 65/614 (11%)
Query 42 SNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIA-SLNIQ 100
S+ TA + I H Q + + +S+T T++
Sbjct 1457 SDVTANSFTVHWVAPRAPITGYIIRHHAEHSAGRPRQ-DRVPPSRNSITLTNLNPGTEYI 1515
Query 101 LTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL 160
+T + + + G + P++L I + + W+ + T
Sbjct 1516 VTIIAVNGREESPPLIG---QQSTVSDVPRDLEVIASTPTSLLISWEPPAVSVRYYRIT- 1571
Query 161 KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKV 220
+ S + + + + A G + Y+
Sbjct 1572 -YGETGGNSPVQEFTVPGSKSTATINNIKPGADYTITLYAVTGRGDSPASSKPVSINYQT 1630
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
+ + P + V + ++ S + + W + + Y + K+ + + +
Sbjct 1631 EIDKPSQMQVTDVQDNS--ISVRWLP---STSPVTGYRVTTAPKNGLGPT--KSQTVSPD 1683
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA--SGITYEDRPSKAPSFWYKIDP 338
++ T++ L+P EYV + +G+ S+ + +T DRP +D
Sbjct 1684 QTEMTIEGLQPTVEYVVSVYAQNRNGE------SQPLVQTAVTNIDRPKGLAFTDVDVD- 1736
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL------QNYTVNATKLTVNLT 392
++++ W+ G++ Y VT + + + + + +L
Sbjct 1737 -------SIKIAWE-----SPQGQVSRYRVTYSSPEDGIHELFPAPDGDEDTAELHGLRP 1784
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK-AFPKDNMLWVEWTTPRESVK 451
Y ++ + +S + A +LK L +WT P +
Sbjct 1785 GSEYTVSVVALHGGMESQP----LIGVQSTAIPAPTNLKFTQVSPTTLTAQWTAPSVKLT 1840
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
Y + V + + G L + Y ++V + P
Sbjct 1841 GYRV--RVTPKEKTGPMKEINLSPDSTSVIVSG-LMVATKYEVSVYALKDTLTSRPAQGV 1897
Query 512 AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNV 570
+ S R + + W + I + + +
Sbjct 1898 VTTLENV-SPPRRARVTDATETTITISWR-TKTET----ITGFQVDAIPANGQTPVQRTI 1951
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFL 630
YT++ L T Y + + D ++P AI P L FL
Sbjct 1952 SPDVRSYTITGLQPGTDYKIHLYTLND--------NARSSPVVIDAS-TAIDAPSNLRFL 2002
Query 631 LTTLLGVLFCFNKR 644
TT +L +
Sbjct 2003 TTTPNSLLVSWQAP 2016
Score = 126 bits (317), Expect = 3e-28, Method: Composition-based stats.
Identities = 68/477 (14%), Positives = 143/477 (30%), Gaps = 50/477 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P NL + + + W R T+ T + S
Sbjct 997 DAPTNLQFVNETDRTVLVTWTPPRARIAGYRLTV---GLTRGGQPKQYNVGPMASKYPLR 1053
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ V + A + F + ++ PP+N +E + + +TWT
Sbjct 1054 NLQPGSEYTVTLMAVKGNQQSPKATGVFTTLQPLRSIPPYN-----TEVTETTIVITWTP 1108
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ + + R P + S S V L P EY + I+ +++
Sbjct 1109 -----APRIGFKLGVRPSQGGE----APREVTSDSGSIVVSGLTPGVEYTYTIQVLRD-- 1157
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
G D +T P+ + + + W+ + I Y
Sbjct 1158 -GQERDAPIVNRVVTPLSPPT-------NLHLEANPDTGVLTVSWERSTTPD----ITGY 1205
Query 367 EVTLTRWKSH-----LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+T T + + + T N ++V + ++A ++
Sbjct 1206 RITTTPTNGQQGTALEEVVHADQSSCTFENRNPGLEYNVSVYTVKDDKESAPISDTVIPE 1265
Query 422 QATHPVMDLKAFPKDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ D+ + + WT ++ Y + + P D+
Sbjct 1266 VPQLTDLSFVDI-TDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSS---VGY 1321
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
Y L Y I+V + G +P ++ +Q +R +G + + W
Sbjct 1322 YTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAVPPPTDLRFTNIGPDTMRVTWA 1378
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNET--AVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
P + N + Y + E +++ S L++L T Y+V +++
Sbjct 1379 PPPSIE----LTNLLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYLVSVSSV 1431
Score = 122 bits (306), Expect = 7e-27, Method: Composition-based stats.
Identities = 69/476 (14%), Positives = 139/476 (29%), Gaps = 51/476 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+KP + + + W T + D
Sbjct 1633 DKPSQMQVTDVQDNSISVRWLPSTSPVTGYRVTTAPKNGLGPTKSQTVSPDQTEMTIEGL 1692
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V V V A+N G+ + +P + ++ +K+ W +
Sbjct 1693 QPT--VEYVVSVYAQNRNGESQ-PLVQTAVTNIDRPK-----GLAFTDVDVDSIKIAWES 1744
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P + +Y + Y + + P D + + L+P +EY +
Sbjct 1745 PQ---GQVSRYRVTYSSPEDGIHELFPAPD--GDEDTAELHGLRPGSEYTVSVVA---LH 1796
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
G S+ G+ P+ + ++ P+ T+ W K+ Y
Sbjct 1797 GGME---SQPLIGVQSTAIPAPTNLKFTQVSPT------TLTAQWTAPSV-----KLTGY 1842
Query 367 EVTLTRWKSHLQNYTVNATK------LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
V +T + +N + ++ + +Y ++ S A + +
Sbjct 1843 RVRVTPKEKTGPMKEINLSPDSTSVIVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE 1902
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ + + + + W T E++ + ++ + + P Q+ R+
Sbjct 1903 NVSPPRRARVTD-ATETTITISWRTKTETITGFQVDAIPANGQTP----VQRTISPDVRS 1957
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
Y L Y I + + + SP I A PS +R N ++ W
Sbjct 1958 YTITGLQPGTDYKIHLYTLNDNARSSPVVIDASTAIDAPS---NLRFLTTTPNSLLVSWQ 2014
Query 541 QLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
I Y I Y E TE T++ L T Y + + A
Sbjct 2015 -----APRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2065
Score = 118 bits (294), Expect = 2e-25, Method: Composition-based stats.
Identities = 72/480 (15%), Positives = 137/480 (29%), Gaps = 59/480 (12%)
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
K W ++T+K + Y +
Sbjct 647 PKTSTGRWKEATIPGHLNSYTIKGLTPGVIYE-------GQLISIQQYGHQEVTRFDFTT 699
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS-EELSSILKLTWTNPSIKSVIILKY 257
A + T + P P + + E +S ++W + S + +
Sbjct 700 SASTPVTSNT-------VTGETAPFSPVVATSESVTEITASSFVVSWVSASDT---VSGF 749
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
++Y + Q D ST +S + DL P +Y+ + + E+GK
Sbjct 750 RVEYELSEEGDEPQY--LDLPSTATSVNIPDLLPGRKYIVNVYQISEEGKQSL------I 801
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL 377
+ P P ++ + W I Y + +
Sbjct 802 LSTSQTTAPDAPPDPTV-----DQVDDTSIVVRW-----SRPQAPITGYRIVYSPSVEGS 851
Query 378 QNY-----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA---THPVMD 429
T N+ L+ +Y T+ +S + D
Sbjct 852 STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVFIQQETTGVPRSDDVPAPKD 911
Query 430 LKAFPKDNM-LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
L+ ++ + + WT P +V Y ++ VL P Q+ + L+
Sbjct 912 LQFVEVTDVKVTIMWTPPNSAVTGYRVD--VLPVNLPGEHG-QRLPVNRNTFAEVTGLSP 968
Query 489 SKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
YL V V+ P + + K P+ ++ ++ W
Sbjct 969 GVTYLFKVFAVHQGRESKPLTAQQTTKLDAPT---NLQFVNETDRTVLVTWTPPRAR--- 1022
Query 549 GFIRNYTIFYR-TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
I Y + T G NV ++Y L +L + Y V + A +G + P+ T
Sbjct 1023 --IAGYRLTVGLTRGGQPKQYNVGPMASKYPLRNLQPGSEYTVTLMAV--KGNQQSPKAT 1078
Score = 114 bits (285), Expect = 2e-24, Method: Composition-based stats.
Identities = 48/384 (13%), Positives = 123/384 (32%), Gaps = 28/384 (7%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + + + + + W P I KY +++R K ++ + +S+
Sbjct 611 PVQVIITETPSQPNSHPIQWNAPEPSH--ITKYILRWRPKTSTG--RWKEATIPGHLNSY 666
Query 285 TVQDLKPFTEYVFRIRCMKEDGK------GYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
T++ L P Y ++ +++ G + + S + T + +
Sbjct 667 TIKGLTPGVIYEGQLISIQQYGHQEVTRFDFTTSASTPVTSNTVTGETAPFSPVVATSES 726
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLA 398
+ + W + + G ++YE++ + + AT + +
Sbjct 727 VTEITASSFVVSWVSASDTVS-GFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 785
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWC 458
+ V + + +++ + P D + V W+ P+ + Y + +
Sbjct 786 IVNVYQISEEGKQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY- 844
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
S + T + L +L Y IT+ V + +P I+ P
Sbjct 845 --SPSVEGSSTELNLPETANSVTL-SDLQPGVQYNITIYAVEENQESTPVFIQQETTGVP 901
Query 519 ----PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI---IGNETAVNVD 571
++ +V + + W N + Y + + + + V+
Sbjct 902 RSDDVPAPKDLQFVEVTDVKVTIMWTPP-----NSAVTGYRVDVLPVNLPGEHGQRLPVN 956
Query 572 SSHTEYTLSSLTSDTLYMVRMAAY 595
+ ++ L+ Y+ ++ A
Sbjct 957 RNTFAE-VTGLSPGVTYLFKVFAV 979
Score = 98.4 bits (243), Expect = 2e-19, Method: Composition-based stats.
Identities = 63/397 (16%), Positives = 112/397 (28%), Gaps = 39/397 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
++PK L+ + ++ W+ + + + + D +
Sbjct 1723 DRPKGLAFTDVDVDSIKIAWE--SPQGQVSRYRVTYSSPEDGIHELFPAPDGDEDTAELH 1780
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V V A + G + I P NL + L WT
Sbjct 1781 GLRPGSEYTVSVVALHG-GMESQPLIGVQSTAIP---APTNLKFTQV--SPTTLTAQWTA 1834
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
PS V + Y ++ K+ + + + +S V L T+Y + +K+
Sbjct 1835 PS---VKLTGYRVRVTPKEKTGPM--KEINLSPDSTSVIVSGLMVATKYEVSVYALKDTL 1889
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
S A G+ P D + T T+ + W+T I +
Sbjct 1890 T------SRPAQGVVTTLENVSPPRRARVTDATET----TITISWRTKTET-----ITGF 1934
Query 367 EVTLTRWKSHLQNY-----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+V V + +T Y L N +S V+
Sbjct 1935 QVDAIPANGQTPVQRTISPDVRSYTITGLQPGTDYKIHLYTLNDNARSSPVVIDASTAI- 1993
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
P N L V W PR + YI+++ +P + V
Sbjct 1994 --DAPSNLRFLTTTPNSLLVSWQAPRARITGYIIKYE--KPGSPPREVVPRPRPGVTEAT 2049
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ G L Y I V + + P + + P
Sbjct 2050 ITG-LEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2085
Score = 59.9 bits (143), Expect = 1e-07, Method: Composition-based stats.
Identities = 53/333 (16%), Positives = 108/333 (32%), Gaps = 36/333 (11%)
Query 501 ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G + ++ Y P + + N ++W+ I Y + +R
Sbjct 593 GIGEWHCQPLQTYPGTTGPVQVI-ITETPSQPNSHPIQWNAPEPSH----ITKYILRWRP 647
Query 561 II--GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT-------- 610
G + YT+ LT +Y ++ + G ++ F FTT
Sbjct 648 KTSTGRWKEATIPGHLNSYTIKGLTPGVIYEGQLISIQQYGHQEVTRFDFTTSASTPVTS 707
Query 611 -----------PKFAQGE-IEAIVVPVCLAFLLT---TLLGVLFCFNKRDLIKKHIWPNV 655
P A E + I + ++ T+ G + + + + ++
Sbjct 708 NTVTGETAPFSPVVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 767
Query 656 PDPSKS-HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPF---PEDLKSL 711
P + S +I P N + S P +D +
Sbjct 768 PSTATSVNIPDLLPGRKYIVNVYQISEEGKQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 827
Query 712 DLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQV 771
+ + + G+ S SS+ ++ + + + + VQY+ +++ +Q
Sbjct 828 VRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 887
Query 772 PSVQVFSRSESTQ-PLLDSEERPEDLQLVDHVD 803
+ VF + E+T P D P+DLQ V+ D
Sbjct 888 STP-VFIQQETTGVPRSDDVPAPKDLQFVEVTD 919
>sp|Q6NWW9|FND3B_MOUSE Fibronectin type III domain-containing
protein 3B OS=Mus musculus OX=10090 GN=Fndc3b PE=1 SV=1
Length=1207
Score = 145 bits (365), Expect = 4e-34, Method: Composition-based stats.
Identities = 86/511 (17%), Positives = 147/511 (29%), Gaps = 49/511 (10%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCTV 184
PE P + +W + + T++ L+ D + C
Sbjct 382 PECPFPPKLAHRSKSSLTLQWKAPIDNGSKITSYLLE--------WDEGKRNSGFRQCFF 433
Query 185 DYSTVYFVN-------IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
+ + A N +G P P ++ +
Sbjct 434 GSQKHCKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPLAPRLVRAGV-- 491
Query 238 SILKLTWTNP---SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ + L W+ P S + VI +IQ D+ + ED TV++LK T+
Sbjct 492 TWITLQWSRPEGCSPEEVITYTLDIQEDENDSHFHPKYTGEDLT-----CTVKNLKRSTQ 546
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y FR+ +GK S SE T DRP P+ P + G+ + W
Sbjct 547 YKFRLTASNMEGK---SCPSEVLVCTTSPDRP-GPPTRPLIKGPVTSHGFS---VKWDA- 598
Query 355 PPFEANGKILDYEVTL---TRWKSHLQ-NYTVNATKLTVNLTNDRYLATLTVRN-LVGKS 409
P +I Y + + T + Y+ +AT+ L L G
Sbjct 599 PKDNGGSEIPKYLLEITDGTPEAGQWEVAYSGSATEYVFTHLKPGTLYKLRACCISTGGH 658
Query 410 DAAVLTIPACDFQATHP---VMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
++P + PK + +EW P + E+ V +
Sbjct 659 SQCSESLPVRTLSLAPGQCRPPRVLGRPKHKGVHLEWDVPASESGCEVSEYSVEMTEPEN 718
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI-KAYLKQAPPSKGPTV 525
+ + GNL Y V + G G + + PP +
Sbjct 719 VASEVYHGPELE--CTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCRAP 776
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
R ++ W+ I Y + + + T + + L
Sbjct 777 RVSFTPDGCVLVGWES--PASPGADISEYRLEWGEDEQ-SLELVYHGPDTCFEMRDLLPA 833
Query 586 TLYMVRMAAYTDEGGKDGPEFTFT-TPKFAQ 615
Y R+ A+ G E TP A
Sbjct 834 AQYCCRLQAFNPAGAGPYSELVHCQTPASAP 864
Score = 144 bits (364), Expect = 5e-34, Method: Composition-based stats.
Identities = 85/507 (17%), Positives = 150/507 (30%), Gaps = 48/507 (9%)
Query 117 GITIISGLPPEKPKNLSCIVNEGKKMRCEWDG--GRETHLETNFTLKSEWATHKFADCKA 174
+ G P+ P + + +W G +TL + +
Sbjct 469 VVCYTLGNIPQMPLAPRLVRAGVTWITLQWSRPEGCSPEEVITYTLDIQEDENDSHFHPK 528
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
+CTV + + + A N GK + +P PP +I
Sbjct 529 YTGEDLTCTV-KNLKRSTQYKFRLTASNMEGKSCPSEVLVCTTSPDRPGPPTRP-LIKGP 586
Query 235 ELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
S + W P I KY ++ D + + + + + + LKP T
Sbjct 587 VTSHGFSVKWDAPKDNGGSEIPKYLLE--ITDGTPEAGQWEVAYSGSATEYVFTHLKPGT 644
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
Y R C+ G S SE T P + P H + V L W
Sbjct 645 LYKLRACCISTGGH---SQCSESLPVRTLSLAPGQCRPPRVLGRPKH----KGVHLEWD- 696
Query 354 LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV----NLTNDRYLATLTVRNLVGKS 409
+P E+ ++ +Y V +T ++ + + +L L Y + N G
Sbjct 697 VPASESGCEVSEYSVEMTE-PENVASEVYHGPELECTVGNLLPGTVYRFRVRALNDGGYG 755
Query 410 D-AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE---SVKKYILEWCVLSDKAP 465
+ V I +F D + V W +P + +Y LEW
Sbjct 756 PYSDVSEITTAAGPPGQCRAPRVSFTPDGCVLVGWESPASPGADISEYRLEWGEDEQSLE 815
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKG-- 522
+ + +L + Y + G G E + + P
Sbjct 816 LVYH------GPDTCFEMRDLLPAAQYCCRLQAFNPAGAGPYSELVHCQTPASAPDPVST 869
Query 523 -------PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT 575
P VL W++ I Y I ++ + V + T
Sbjct 870 LCVLEEEPPSAHPDSPSVCLVLNWEE--PCNNGSEILAYNI-----DLGDSCITV-GNTT 921
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ + +L +T Y +R+ A + G
Sbjct 922 THVMKNLLPETTYRIRIQAINEIGVGP 948
Score = 133 bits (335), Expect = 2e-30, Method: Composition-based stats.
Identities = 89/512 (17%), Positives = 157/512 (31%), Gaps = 40/512 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSC 182
PP +P L +WD ++ + L+ T + + +
Sbjct 577 PPTRP--LIKGPVTSHGFSVKWDAPKDNGGSEIPKYLLEITDGTPEAGQWEVAYSGSATE 634
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
V ++ + G + P V+ + + L
Sbjct 635 YVFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSLAPGQCRPPRVLGRPKHKG-VHL 693
Query 243 TWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
W P+ +S + +Y+++ + + E TV +L P T Y FR+R
Sbjct 694 EWDVPASESGCEVSEYSVEM-----TEPENVASEVYHGPELECTVGNLLPGTVYRFRVRA 748
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ + G G +SD SE + + P S T V + W+ P
Sbjct 749 LNDGGYGPYSDVSEITTA-------AGPPGQCRAPRVSFTPDG-CVLVGWE--SPASPGA 798
Query 362 KILDYEVTLTRWKSHLQNYTV-NATKLTVN--LTNDRYLATLTVRNLVGKSDAAVLTIPA 418
I +Y + + L+ T + L +Y L N G + L
Sbjct 799 DISEYRLEWGEDEQSLELVYHGPDTCFEMRDLLPAAQYCCRLQAFNPAGAGPYSELVHCQ 858
Query 419 CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG--- 475
A PV L ++ P +L W + I + + G
Sbjct 859 TPASAPDPVSTLCVLEEEPPS----AHPDSPSVCLVLNWEEPCNNGSEILAYNIDLGDSC 914
Query 476 ---TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGK 532
T++ NL Y I + + G G + P P + G
Sbjct 915 ITVGNTTTHVMKNLLPETTYRIRIQAINEIGVGPFSQFIKAKTRPLPPSPPRLECAASGP 974
Query 533 NEAVLEW-DQLPVDVQNGFIRNYTIFYRTIIGNETAVNV-DSSHTEYTLSSLTSDTLYMV 590
L+W D G + YT+ + N+ +++ Y + LT T Y
Sbjct 975 QSLKLKWGDSNSKTHAAGDMV-YTL--QLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSF 1031
Query 591 RMAAYTDEGGKDGPEF-TFTTPKFAQGEIEAI 621
R+ A ++ G E TF+T K ++A
Sbjct 1032 RIQAMSEAGEGPYSETYTFSTTKSVPPTLKAP 1063
Score = 130 bits (326), Expect = 2e-29, Method: Composition-based stats.
Identities = 72/404 (18%), Positives = 121/404 (30%), Gaps = 34/404 (8%)
Query 233 SEELSSILKLTWTNP-------SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
S + + L+W P Y + K +I +
Sbjct 288 SNIQARAVVLSWAPPVGLSCGPHGGLSFPYSYEVALSDKGRDGKYKIIY---SGEELECN 344
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA-PSFWYKIDPSHTQGY 344
++DL+P T+Y R+ + KG SE S T+ P P +
Sbjct 345 LKDLRPATDYHVRVYAVYNSVKGSC---SEPVSFTTHSCAPECPFPPKLAH------RSK 395
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN-----YTVNATKLTVNLTNDRYLAT 399
++ L WK P + KI Y + K + + KLT Y
Sbjct 396 SSLTLQWKA--PIDNGSKITSYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLCPAMGYTFR 453
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRESVKKYILEWC 458
L RN +G S + + + + + ++W+ P + ++ +
Sbjct 454 LAARNDIGTSGYSQEVVCYTLGNIPQMPLAPRLVRAGVTWITLQWSRPEGCSPEEVITYT 513
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA-YLKQA 517
+ + + + + T NL S Y +T +G P +
Sbjct 514 LDIQEDENDSHFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNMEGKSCPSEVLVCTTSPD 573
Query 518 PPSKGPTVRTK-KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET--AVNVDSSH 574
P K V + ++WD P D I Y + V S
Sbjct 574 RPGPPTRPLIKGPVTSHGFSVKWDA-PKDNGGSEIPKYLLEITDGTPEAGQWEVAYSGSA 632
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF-TFTTPKFAQGE 617
TEY + L TLY +R + G E T A G+
Sbjct 633 TEYVFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSLAPGQ 676
Score = 130 bits (326), Expect = 2e-29, Method: Composition-based stats.
Identities = 83/525 (16%), Positives = 157/525 (30%), Gaps = 34/525 (6%)
Query 83 NRTASSVTFTDI---ASLNIQLTCNILTFGQLEQNVYGITIISGLP--PEKPKNLSCIVN 137
+ +A+ FT + ++ C + +S P P+ L
Sbjct 629 SGSATEYVFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSLAPGQCRPPRVLG--RP 686
Query 138 EGKKMRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV 196
+ K + EWD E+ E + S T P + +
Sbjct 687 KHKGVHLEWDVPASESGCEVS--EYSVEMTEPENVASEVYHGPELECTVGNLLPGTVYRF 744
Query 197 WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK 256
V A N G ++ P V + + + + W +P+ I +
Sbjct 745 RVRALNDGGYGPYSDVSEITTAAGPPGQCRAPRVSFTPD--GCVLVGWESPASPGADISE 802
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y +++ +D + + + F ++DL P +Y R++ G G +SE
Sbjct 803 YRLEW-GEDEQSLELVYH----GPDTCFEMRDLLPAAQYCCRLQAFNPAGAG---PYSEL 854
Query 317 ASGITYEDRPSK--APSFWYKIDPSHTQGYRTV--QLVWKTLPPFEANGKILDYEVTLTR 372
T P + PS +V L W+ P +IL Y + L
Sbjct 855 VHCQTPASAPDPVSTLCVLEEEPPSAHPDSPSVCLVLNWEE--PCNNGSEILAYNIDL-- 910
Query 373 WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA 432
S + + L Y + N +G + P A
Sbjct 911 GDSCITVGNTTTHVMKNLLPETTYRIRIQAINEIGVGPFSQFIKAKTRPLPPSPPRLECA 970
Query 433 FPKDNMLWVEW-TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
L ++W + ++ + + + + + TY L E C
Sbjct 971 ASGPQSLKLKWGDSNSKTHAAGDMVYTLQLEDRNKRFISIYRGPS--HTYKVQRLTEFTC 1028
Query 492 YLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
Y + + G G E+ ++ P R ++ N + W+ +P G
Sbjct 1029 YSFRIQAMSEAGEGPYSETYTFSTTKSVPPTLKAPRVTQLEGNSCEIFWETVPPM--RGD 1086
Query 551 IRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
+Y + +E + +S L S+T Y R+ A
Sbjct 1087 PVSYVLQVLVGRDSEYKQVYKGEEATFQISGLQSNTDYRFRVCAC 1131
Score = 47.9 bits (112), Expect = 4e-04, Method: Composition-based stats.
Identities = 32/177 (18%), Positives = 61/177 (34%), Gaps = 18/177 (10%)
Query 134 CIVNEGKKMRCEW-DGGRETHL--ETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY 190
C + + ++ +W D +TH + +TL+ E +F P+
Sbjct 969 CAASGPQSLKLKWGDSNSKTHAAGDMVYTLQLEDRNKRFISIYR---GPSHTYKVQRLTE 1025
Query 191 FVNIEVWVEAENALGKVT-SDHINFDPVYKVKP--NPPHNLSVINSEELSSILKLTWTNP 247
F ++A + G+ S+ F V P P V E S ++ W
Sbjct 1026 FTCYSFRIQAMSEAGEGPYSETYTFSTTKSVPPTLKAP---RVTQLEGNS--CEIFWETV 1080
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ Y +Q S + Q+ ++F + L+ T+Y FR+ +
Sbjct 1081 PPMRGDPVSYVLQVLVGRDSEYKQVY----KGEEATFQISGLQSNTDYRFRVCACRR 1133
>sp|O18796|IL6RA_PIG Interleukin-6 receptor subunit alpha OS=Sus
scrofa OX=9823 GN=IL6R PE=2 SV=2
Length=467
Score = 139 bits (349), Expect = 1e-33, Method: Composition-based stats.
Identities = 56/266 (21%), Positives = 105/266 (39%), Gaps = 25/266 (9%)
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRET 152
+ S+ + + N + Q + ++ PPE+P+ LSC + CEW
Sbjct 83 LKSVQLSDSGNYSCY-QDGVPAGSVRLLVDAPPEEPQ-LSCFRKSPLSNVGCEWRPRSPP 140
Query 153 HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN-----------IEVWVEAE 201
T K+ KF + + D C F V +
Sbjct 141 SPTT----KAVLLVRKFQNSPVE-DFQEPCQYSLEAQRFFCQLAVPEGDNSFHIVTLCVA 195
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII--LKYNI 259
N+ G +S F+ ++P+PP N++V + L +TW +P + L++ +
Sbjct 196 NSAGSQSSTPQTFEGYGILQPDPPVNITVSAVDRNPRWLSVTWQDPPSWNSYFYRLQFEL 255
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+YR + + T++ ++ + + D +V ++R +E G G WS+WS+E +G
Sbjct 256 RYRAERSKTFTTWMVKEL---QHHCIIHDAWSGMRHVVQLRAQEEFGHGLWSEWSQEVTG 312
Query 320 ITY-EDRPSKAPSFWYKIDPSHTQGY 344
I + E R S A + + T
Sbjct 313 IPWTESRSSPAETELPLSTQAPTTNE 338
Score = 35.6 bits (80), Expect = 2.3, Method: Composition-based stats.
Identities = 25/154 (16%), Positives = 44/154 (29%), Gaps = 13/154 (8%)
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK----ILDYEVTLTRWKSHLQNYTVN 383
AP ++ V W+ P K + ++ + Y++
Sbjct 111 DAPPEEPQLSCFRKSPLSNVGCEWRPRSPPSPTTKAVLLVRKFQNSPVEDFQEPCQYSLE 170
Query 384 ATKLTVNL-----TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
A + L N ++ TL V N G + T P +++ D
Sbjct 171 AQRFFCQLAVPEGDNSFHIVTLCVANSAGSQSSTPQTFEGYGILQPDPPVNITVSAVDRN 230
Query 439 ---LWVEWTTPRESVKK-YILEWCVLSDKAPCIT 468
L V W P Y L++ + T
Sbjct 231 PRWLSVTWQDPPSWNSYFYRLQFELRYRAERSKT 264
>sp|O09127|EPHA8_MOUSE Ephrin type-A receptor 8 OS=Mus musculus
OX=10090 GN=Epha8 PE=1 SV=2
Length=1004
Score = 143 bits (361), Expect = 1e-33, Method: Composition-based stats.
Identities = 54/211 (26%), Positives = 80/211 (38%), Gaps = 18/211 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADC-KAKRDT 178
PP P NL VN G + EW GR + WA C R
Sbjct 327 PPSAPVNLISSVN-GTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSHCEACGSGTRFV 385
Query 179 PTSCTVDYSTVY------FVNIEVWVEAENALGKVTSDHINFDPVYKVK-PNPPHNLSVI 231
P ++ +++ +N W+EA N + ++ + + V P + VI
Sbjct 386 PQQTSLAQASLLVANLLAHMNYSFWIEAVNGVSNLSPEPRSAAVVNITTNQAAPSQVVVI 445
Query 232 NSEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
E + + L W P + IIL+Y I+Y KD S + + TV LK
Sbjct 446 RQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQS---YSTLKAVTTRATVSGLK 502
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
P T YVF++R G G +S E +G
Sbjct 503 PGTRYVFQVRARTSAGCGRFSQAMEVETGKP 533
Score = 106 bits (265), Expect = 4e-22, Method: Composition-based stats.
Identities = 40/208 (19%), Positives = 72/208 (35%), Gaps = 19/208 (9%)
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITD- 469
AA+ A + ++L + + +EW P + + + + + + P
Sbjct 315 AALDPPSAACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSH 374
Query 470 ----------WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYL 514
Q+ + L NL Y + V SPE +
Sbjct 375 CEACGSGTRFVPQQTSLAQASLLVANLLAHMNYSFWIEAVNGVSNLSPEPRSAAVVNITT 434
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNVDSS 573
QA PS+ +R ++ G+ L W + + NG I Y I Y ++ + +
Sbjct 435 NQAAPSQVVVIRQERAGQTSVSLLWQE--PEQPNGIILEYEIKYYEKDKEMQSYSTLKAV 492
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
T T+S L T Y+ ++ A T G
Sbjct 493 TTRATVSGLKPGTRYVFQVRARTSAGCG 520
Score = 79.9 bits (195), Expect = 6e-14, Method: Composition-based stats.
Identities = 46/211 (22%), Positives = 72/211 (34%), Gaps = 26/211 (12%)
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT-KDASTW--- 269
DP PP + S + + L W P + +I Y W
Sbjct 317 LDPPSAACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGG---RSDITYNAVCRRCPWALS 373
Query 270 --------SQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
++ P+ T+ ++S V +L Y F I + S IT
Sbjct 374 HCEACGSGTRFVPQQTSLAQASLLVANLLAHMNYSFWIEAVNGVSNLSPEPRSAAVVNIT 433
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
APS I G +V L+W+ P + NG IL+YE+ +Q+Y+
Sbjct 434 TNQA---APSQVVVIRQER-AGQTSVSLLWQE--PEQPNGIILEYEIKYYEKDKEMQSYS 487
Query 382 VN---ATKLTVNLTN--DRYLATLTVRNLVG 407
T+ TV+ RY+ + R G
Sbjct 488 TLKAVTTRATVSGLKPGTRYVFQVRARTSAG 518
Score = 69.1 bits (167), Expect = 1e-10, Method: Composition-based stats.
Identities = 34/219 (16%), Positives = 58/219 (26%), Gaps = 29/219 (13%)
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR--WKSHLQNYT 381
RP AP ++ + +V L W I Y R W
Sbjct 325 TRPPSAP-----VNLISSVNGTSVTLEWAPPLDPGGRSDIT-YNAVCRRCPWALSHCEAC 378
Query 382 VNATKLTVNLTNDR--------------YLATLTVRNLVG-KSDA----AVLTIPACDFQ 422
+ T+ T+ Y + N V S AV+ I
Sbjct 379 GSGTRFVPQQTSLAQASLLVANLLAHMNYSFWIEAVNGVSNLSPEPRSAAVVNITTNQAA 438
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
+ V+ + + + W P E ILE+ + + V
Sbjct 439 PSQVVVIRQERAGQTSVSLLWQEP-EQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRAT 497
Query 483 RGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPS 520
L Y+ V + G G ++++ + P
Sbjct 498 VSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPR 536
>sp|Q63870|CO7A1_MOUSE Collagen alpha-1(VII) chain OS=Mus musculus
OX=10090 GN=Col7a1 PE=1 SV=3
Length=2944
Score = 144 bits (363), Expect = 1e-33, Method: Composition-based stats.
Identities = 81/522 (16%), Positives = 155/522 (30%), Gaps = 66/522 (13%)
Query 131 NLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY 190
NL I G+++R W+ E FT+++ + T D V
Sbjct 514 NLQAIELPGQRVRVSWNP-VPGATEYRFTVRTTQGVERTLLLPGS-----QTTFDLDDVR 567
Query 191 -FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW-TNPS 248
++ V V A + + + + P L V+ S+ ++ +++ W P
Sbjct 568 AGLSYTVRVSARVGAQEGDASILTIHRDPEAPLVVP-GLRVVASD--ATRIRVAWGLVPG 624
Query 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
+ I +RT S+ D+ T + L+P T Y + ++ +G
Sbjct 625 AS-----GFRISWRTGSGPESSRTLTPDSTVT----DILGLQPSTSYQVAVSALRGREEG 675
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
I P + G +V + W +P Y V
Sbjct 676 PP-------VVIVARTDPLGPVRRVHL----TQAGSSSVSITWTGVPGA------TGYRV 718
Query 369 TLTRWKSHLQNYTVNATKLTVNLTN----DRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
+ ++ V+ + Y+ + A + +
Sbjct 719 SWHSGHGPEKSLLVSGDATVAEIDGLEPDTEYIVRVRTHVAGVDGAPASVVVRTAPEPVG 778
Query 425 HPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
++L V W + Y L W + G +R
Sbjct 779 SVSKLQILNASSDVLRVTWVGVPGATS-YKLAW---GRSEGGPMKHRILPGNKESAEIRD 834
Query 485 NLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
L Y + VT + D G+P SI A P+ T++ + G++ L W+ +P
Sbjct 835 -LEGGVSYSVRVTALVGDREGAPVSIVITTPPATPALLETLQVVQSGEHSLRLRWEPVPG 893
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVR------------- 591
+ + ++ G E ++ + Y L L T Y V
Sbjct 894 AP------GFRLHWQPEGGQEQSLTLGPESNSYNLVGLEPATKYQVWLTVLGQTGEGPPR 947
Query 592 -MAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLT 632
+ AYT+ E + V +++L+
Sbjct 948 KVTAYTEPSHIPSTELRVVDTSIDSVTLTWTPVSGASSYILS 989
Score = 129 bits (323), Expect = 7e-29, Method: Composition-based stats.
Identities = 80/499 (16%), Positives = 146/499 (29%), Gaps = 59/499 (12%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDG--GRETHLETNFT-LKSEWATHKFADCKA 174
+T+ S P P++L + +R +W G T + +T L +
Sbjct 225 VTLPSDDTPSGPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEV 284
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEA--ENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
+ T + +V V A N++G+ S + L +
Sbjct 285 NIPAGETSTRLQGLRPLTDYQVTVVALYANSIGEAVS--------GTARTTAKEGLELSL 336
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
S L + W + Y + +R Q +D + + S + L+P
Sbjct 337 QNITSHSLLVAWRRVPGANG----YRVTWRDLSGGPTQQ---QDLSPGQGSVFLDHLEPG 389
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
T+Y + + G A+ +T S + I ++ L W
Sbjct 390 TDYEVTVSALFGHSVG-------PAASLTARTASSVEQTLHPII-----LSPTSILLSWN 437
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNY------TVNATKLTVNLTNDRYLATLTVRNLV 406
+P Y + R V +L Y TL
Sbjct 438 LVPEA------RGYRLEWRRESGLETPQKVELPPDVTRHQLDGLQPGTEYRLTLYTLLEG 491
Query 407 GKSDAAVLTIPACDFQATHPVMDLKAFPKDN-MLWVEWTTPRESVKKYILEWCVLSDKAP 465
+ +P Q PVM+L+A + V W + E+
Sbjct 492 REVATPATVVPTGLEQLVSPVMNLQAIELPGQRVRVSWNPVPGAT-----EYRFTVRTTQ 546
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
+ G+ L ++ Y + V+ G + + P P +
Sbjct 547 GVERTLLLPGSQTTFDL-DDVRAGLSYTVRVSARVGAQEGDASILTIHRDPEAPLVVPGL 605
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
R + W +P + I +RT G E++ + T + L
Sbjct 606 RVVASDATRIRVAWGLVPGAS------GFRISWRTGSGPESSRTLTPDSTVTDILGLQPS 659
Query 586 TLYMVRMAAYTDEGGKDGP 604
T Y V ++A G ++GP
Sbjct 660 TSYQVAVSAL--RGREEGP 676
Score = 109 bits (271), Expect = 1e-22, Method: Composition-based stats.
Identities = 54/292 (18%), Positives = 93/292 (32%), Gaps = 43/292 (15%)
Query 320 ITYEDRPSKAPSFWYKIDPS----HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
T P PS P +++++ W A+G + Y+V T
Sbjct 218 TTAGGVPVTLPSDDTPSGPRDLVLSEPSSQSLRVQW-----TAASGPVTGYKVQYTPLTG 272
Query 376 HLQNYT-----------VNATKLTVNLTNDRYLATLTV--RNLVGKSDAAVLTIPACDFQ 422
Q +T+L Y T+ N +G++ + A +
Sbjct 273 LGQPLPSERQEVNIPAGETSTRLQGLRPLTDYQVTVVALYANSIGEAVSGTARTTAKEGL 332
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
+ L+ + L V W + Y + W LS T Q +L
Sbjct 333 E----LSLQNI-TSHSLLVAWRRVPGA-NGYRVTWRDLSGG---PTQQQDLSPGQGSVFL 383
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
+L Y +TV+ ++ G S+ A S T+ + +L W+ +
Sbjct 384 -DHLEPGTDYEVTVSALFGHSVGPAASLTART---ASSVEQTLHPIILSPTSILLSWNLV 439
Query 543 PVDVQNGFIRNYTIFYRTIIGNET--AVNVDSSHTEYTLSSLTSDTLYMVRM 592
P R Y + +R G ET V + T + L L T Y + +
Sbjct 440 P------EARGYRLEWRRESGLETPQKVELPPDVTRHQLDGLQPGTEYRLTL 485
Score = 89.5 bits (220), Expect = 1e-16, Method: Composition-based stats.
Identities = 41/239 (17%), Positives = 76/239 (32%), Gaps = 14/239 (6%)
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS---DKA 464
+ V D + P + + P L V+WT V Y +++ L+
Sbjct 218 TTAGGVPVTLPSDDTPSGPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPL 277
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
P T L+G L Y +TV +YA+ G S A +G
Sbjct 278 PSERQEVNIPAGETSTRLQG-LRPLTDYQVTVVALYANSIGEAVSGTARTTAK---EGLE 333
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI-IGNETAVNVDSSHTEYTLSSLT 583
+ + + + ++ W ++P Y + +R + G ++ L L
Sbjct 334 LSLQNITSHSLLVAWRRVPGAN------GYRVTWRDLSGGPTQQQDLSPGQGSVFLDHLE 387
Query 584 SDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFN 642
T Y V ++A T T + + I++ L L+ +
Sbjct 388 PGTDYEVTVSALFGHSVGPAASLTARTASSVEQTLHPIILSPTSILLSWNLVPEARGYR 446
>sp|Q9UQP3|TENN_HUMAN Tenascin-N OS=Homo sapiens OX=9606 GN=TNN
PE=1 SV=2
Length=1299
Score = 143 bits (361), Expect = 2e-33, Method: Composition-based stats.
Identities = 83/481 (17%), Positives = 156/481 (32%), Gaps = 68/481 (14%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGR--ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P+ L + N + W+ + +L + + L E + + P
Sbjct 264 TPQGLQLLKNTEDSLLVSWEPSSQVDHYLLSYYPLGKELSGKQIQ-------VPKEQHSY 316
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS----EELSSILK 241
+ V N +V+S + +L+V+ + +E + L
Sbjct 317 EILGLLPGTKYIVTLRNVKNEVSSSPQHLLAT--------TDLAVLGTAWVTDETENSLD 368
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+ W NPS + + Y ++Y +++ ++ +S + + L P TEY +
Sbjct 369 VEWENPSTE---VDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVP 425
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
M+ + +G +G T D P+ + T + W +
Sbjct 426 MRGELEGKP----ILLNGRTEIDSPTN--------VVTDRVTEDTATVSWDPVQAV---- 469
Query 362 KILDYEVTLTRWKSHLQNYTVN----ATKLTVNLTNDRYLATLTV-RNLVGKSDAAVLTI 416
I Y V T + V+ +T LT + Y + R G A +
Sbjct 470 -IDKYVVRYTSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNAL 528
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
D P + +N + W + ++ KY++ + D+ + G
Sbjct 529 TEID----SPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETR----EVLVGK 580
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS---KGPTVRTKKVGKN 533
+ + L Y + V G ES KA P+ + T +V +N
Sbjct 581 EQSSTVLTGLRPGVEYTVHV----WAQKGDRESKKADTN--APTDIDSPKNLVTDRVTEN 634
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
A + WD + I Y + Y + G V V + L+ L YMV +
Sbjct 635 MATVSWDPVQAA-----IDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVW 689
Query 594 A 594
A
Sbjct 690 A 690
Score = 131 bits (330), Expect = 8e-30, Method: Composition-based stats.
Identities = 77/474 (16%), Positives = 145/474 (31%), Gaps = 56/474 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P N+ WD + + ++ A + +D ++
Sbjct 444 DSPTNVVTDRVTEDTATVSWDP--VQAVIDKYVVRYTSADGDTKEMAVHKDESSTVLTGL 501
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ VW E N G +D + + P NL E ++ + +W
Sbjct 502 KPGEAYKVYVWAERGNQ-GSKKADTNALTEI-----DSPANLVTDRVTENTATI--SWDP 553
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
I KY ++Y + D ++ +SS + L+P EY +
Sbjct 554 VQAT---IDKYVVRYTSADDQETREV---LVGKEQSSTVLTGLRPGVEYTVHV------- 600
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV-QLVWKTLPPFEANGKILD 365
W+++ + + + + + + + W + I
Sbjct 601 ------WAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA-----IDK 649
Query 366 YEVTLTRWKSHLQNYTV----NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
Y V T + V ++T LT Y+ + + G ++ A
Sbjct 650 YVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQ--KGDQESKKADTKA-QT 706
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
P + +NM V W R ++ +Y++ + D + G +
Sbjct 707 DIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETR----EVPVGKEQSST 762
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLK-QAPPSKGPTVRTKKVGKNEAVLEWD 540
+ L Y + V G+ ES KA K Q + T V +N A + WD
Sbjct 763 VLTGLRPGVEYTVHV----WAQKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWD 818
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
+ I Y + Y + G V V + L+ L Y V + A
Sbjct 819 PVQAT-----IDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWA 867
Score = 125 bits (314), Expect = 7e-28, Method: Composition-based stats.
Identities = 86/481 (18%), Positives = 142/481 (30%), Gaps = 60/481 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
+ P NL WD + T +T + T + K + S TV
Sbjct 532 DSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQ-----SSTV 586
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
V V V A+ G S + + + + P NL E + ++W
Sbjct 587 LTGLRPGVEYTVHVWAQK--GDRESKKADTNAPTDI--DSPKNLVTDRVTEN--MATVSW 640
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
I KY ++Y + T +SS + L+P EY+ + K
Sbjct 641 DP---VQAAIDKYVVRYTSAGGETRE----VPVGKEQSSTVLTGLRPGMEYMVHVWAQKG 693
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
D E T +P + + W + I
Sbjct 694 DQ--------ESKKADTKAQTDIDSPQNLVTDRVTENMA----TVSWDPVRAT-----ID 736
Query 365 DYEVTLTRWKSHLQNYTV-----NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
Y V T K ++T LT Y + + +S A
Sbjct 737 RYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTD 796
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
P + + +N V W + ++ +Y++ + + + + G
Sbjct 797 I---DSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVP-----VGKEQS 848
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKK-VGKNEAVLE 538
+ + L Y + V G+ ES KA K GP V +N A +
Sbjct 849 STVLTGLRPGMEYTVHV----WAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVS 904
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
WD + I Y + Y + G V V H+ L+ L YMV + A
Sbjct 905 WDPVQAT-----IDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGA 959
Query 599 G 599
Sbjct 960 Q 960
Score = 118 bits (296), Expect = 8e-26, Method: Composition-based stats.
Identities = 76/488 (16%), Positives = 145/488 (30%), Gaps = 53/488 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ PKNL WD + ++ A + + ++ ++
Sbjct 621 DSPKNLVTDRVTENMATVSWDP--VQAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGL 678
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ VW + K + D + + P NL E + ++W
Sbjct 679 RPGMEYMVHVWAQ------KGDQESKKADTKAQTDIDSPQNLVTDRVTEN--MATVSWDP 730
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
I +Y ++Y + ++P +SS + L+P EY + K
Sbjct 731 VRAT---IDRYVVRYTSAKDGETREVP---VGKEQSSTVLTGLRPGVEYTVHVWAQKGAQ 784
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
+ +D T D P + W + T + W + I Y
Sbjct 785 ESKKAD----TKAQTDIDSPQNLVTDWVTEN--------TATVSWDPVQAT-----IDRY 827
Query 367 EVTLTRWKSHLQNYTV----NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
V T + V ++T LT Y + + +S A +
Sbjct 828 VVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKA---DTKAQTE 884
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
P + + +NM V W + ++ KY++ + + + G H + +
Sbjct 885 IDGPKNLVTDWVTENMATVSWDPVQATIDKYMVRYTSADGETREVP-----VGKEHSSTV 939
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
L Y++ V KA + PP +R V ++ +L W
Sbjct 940 LTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPPR---NLRPSAVTQSGGILTWTPP 996
Query 543 PVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
I Y + Y+ G + + + L L Y V + A+
Sbjct 997 SAQ-----IHGYILTYQFPDGTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSR 1051
Query 603 GPEFTFTT 610
T +T
Sbjct 1052 NVSTTLST 1059
Score = 67.6 bits (163), Expect = 5e-10, Method: Composition-based stats.
Identities = 34/178 (19%), Positives = 61/178 (34%), Gaps = 16/178 (9%)
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
Q P ++ L V W P V Y+L + L + ++ Q + +Y
Sbjct 261 QVVTPQGLQLLKNTEDSLLVSWE-PSSQVDHYLLSYYPLGKE---LSGKQIQVPKEQHSY 316
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
L Y++T+ V + SP+ + A A +N +EW+
Sbjct 317 EILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTA---WVTDETENSLDVEWEN 373
Query 542 LPVDVQNGFIRNYTIFYRTIIGNET-AVNVDSS---HTEYTLSSLTSDTLYMVRMAAY 595
+ + Y + Y + G E V V S + Y ++ L T Y + +
Sbjct 374 PSTE-----VDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPM 426
>sp|Q86VF2|IGFN1_HUMAN Immunoglobulin-like and fibronectin type
III domain-containing protein 1 OS=Homo sapiens OX=9606 GN=IGFN1
PE=1 SV=2
Length=1251
Score = 143 bits (359), Expect = 2e-33, Method: Composition-based stats.
Identities = 90/498 (18%), Positives = 157/498 (32%), Gaps = 41/498 (8%)
Query 125 PPEKPKNLS-CIVNEGKKMRCEWDGGRETHLETN--FTLKSEWATHKFADCKAKRDTPTS 181
PP+ P + C + W R+ T + ++ A + ++
Sbjct 646 PPQGPMEVQDCHRA---GVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPADST 702
Query 182 CTVDYSTVYFVNIEVWVEAENALGK---VTSDHINFDPVYKVK-PNPPHNLSVINSEELS 237
D V A + G + S+ I P K P+ P LS S
Sbjct 703 TFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPAILSA-----SS 757
Query 238 SILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
+ LTWT P IL Y I+ R K ++TW+ + D +TV D++ +Y
Sbjct 758 QGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVN--DQPVPERRWTVADVRQGCQYE 815
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
FR+ + G G S+ P + P + + + ++ L W
Sbjct 816 FRVTAVAPSGPGEPGPPSDAVFARD----PMRPPGLVRNLQVTD-RSNTSITLSWAGPDT 870
Query 357 FEANGKILDYEVTLTRWKS------HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD 410
E + Y V L S H+ V + Y +T N G+S
Sbjct 871 QEGDEA-QGYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQ 929
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNMLWVE-----WTTPR-ESVKKYILEWCVLSDKA 464
+ L T L ++L V+ E++ + W
Sbjct 930 PSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFEAMPMPEVTWLKDGLPL 989
Query 465 PCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
P + +DG L++S Y + + + I+ A P
Sbjct 990 PKRSVTVTKDGLTQLLIPVAGLSDSGLYTVVLRTLQGKEVAHSFRIRV---AACPQAPGP 1046
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAVNVDSSHTEYTLSSLT 583
+ ++ EW+ P + Q+ + +Y +F R+ G +TL +
Sbjct 1047 IHLQENVPGTVTAEWEPSPDEAQDVPL-HYAVFTRSSAHGPWHEAADRIHTNRFTLLGIL 1105
Query 584 SDTLYMVRMAAYTDEGGK 601
Y R+ A + G
Sbjct 1106 PGHEYHFRVVAKNELGAS 1123
Score = 100 bits (248), Expect = 5e-20, Method: Composition-based stats.
Identities = 59/416 (14%), Positives = 115/416 (28%), Gaps = 27/416 (6%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCT 183
P P LS + + W R + ++ + P
Sbjct 747 PSAPAILSA---SSQGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERRW 803
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS-SILKL 242
E V A G + + PP + + + S + + L
Sbjct 804 TVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITL 863
Query 243 TWTNPSIKSVII-LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+W P + Y ++ + D+ W +P +++T + L+P Y R+
Sbjct 864 SWAGPDTQEGDEAQGYVVELCSSDSLQW--LPCHVGTVPVTTYTAKGLRPGEGYFVRVTA 921
Query 302 MKEDGKGYWSDWSEEASGITY-EDRPSKA-PSFWYKIDPSH-----TQGYRTVQLVWKTL 354
+ E G+ S+ ++ T + P P F V + ++ +
Sbjct 922 VNEGGQ------SQPSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFEAM 975
Query 355 PPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVL 414
P E + L + + + + V +D L T+ +R L GK A
Sbjct 976 PMPEVTWLKDG--LPLPKRSVTVTKDGLTQLLIPVAGLSDSGLYTVVLRTLQGKEVAHSF 1033
Query 415 TIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED 474
I + L+ + EW + + L + V + + + D
Sbjct 1034 RIRVAACPQAPGPIHLQENVPGT-VTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAAD 1092
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKV 530
+ + Y V G P P + K
Sbjct 1093 RIHTNRFTLLGILPGHEYHFRVVAKNELGASKPS--DTSQPWCIPRQRDRFTVKAP 1146
Score = 94.9 bits (234), Expect = 2e-18, Method: Composition-based stats.
Identities = 63/355 (18%), Positives = 110/355 (31%), Gaps = 36/355 (10%)
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF---EANGKILDYEVTLTRWKSHLQNY 380
D+P P ++ H G V L W+ +++ +
Sbjct 642 DKPD-PPQGPMEVQDCHRAG---VCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEA 697
Query 381 TVNATKLTVN--LTNDRYLATLTVRNLVGKSD----AAVLTIPACDFQATHPVMDLKAFP 434
++T T +Y + G + +L P +A L A
Sbjct 698 PADSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPAILSA-- 755
Query 435 KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ--QEDGTVHRTYLRGNLAESKCY 492
+ + WT PR +IL + ++ + W + R + ++ + Y
Sbjct 756 SSQGITLTWTAPRGPGSAHILGY-LIERRKKGSNTWTAVNDQPVPERRWTVADVRQGCQY 814
Query 493 LITVTPVYADGPGSPES----IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
VT V GPG P + A PP ++ L W D Q
Sbjct 815 EFRVTAVAPSGPGEPGPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAG--PDTQE 872
Query 549 GF-IRNYTIFYRTIIG-NETAVNVDS-SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
G + Y + + +V + T YT L Y VR+ A + G
Sbjct 873 GDEAQGYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQ--- 929
Query 606 FTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHI-WPNVPDPS 659
P ++A+ V VC FL+ + L D ++ + + +P P
Sbjct 930 -----PSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFEAMPMPE 979
Score = 51.0 bits (120), Expect = 5e-05, Method: Composition-based stats.
Identities = 30/159 (19%), Positives = 51/159 (32%), Gaps = 18/159 (11%)
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVR-TKKVGKNEAVLEWDQLPVDVQNGF 550
Y +T+ + +++ K PP V+ + G L W P D
Sbjct 621 YSVTLRS-EGGSVQAELTLQVIDKPDPPQGPMEVQDCHRAG---VCLRWRP-PRDNGGRT 675
Query 551 IRNYTIFYRTIIGNETAVNV---DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG--PE 605
+ Y + R G T + V + T +T + + Y R+ A T EG + E
Sbjct 676 VECYVVERRQA-GRSTWLKVGEAPADSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESE 734
Query 606 FTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
P+ P A L + G+ +
Sbjct 735 EILVAPE------ALPKAPSAPAILSASSQGITLTWTAP 767
>sp|Q9P218|COKA1_HUMAN Collagen alpha-1(XX) chain OS=Homo sapiens
OX=9606 GN=COL20A1 PE=1 SV=4
Length=1284
Score = 142 bits (358), Expect = 3e-33, Method: Composition-based stats.
Identities = 79/487 (16%), Positives = 139/487 (29%), Gaps = 40/487 (8%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
P +L +R W L+ ++ + + P + T ++
Sbjct 379 APTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGG---TPREVVVEGPAASTELHN 435
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP 247
V V G + P PP ++ + + LTW
Sbjct 436 LASRTEYLVSVFPIYEGGVGEG----LRGLVTTAPLPP-PRALTLAAVTPRTVHLTWQPS 490
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
+ + Y ++ + R + L+P +Y ++ ++
Sbjct 491 AGATH----YLVRCSPASPKGEEEEREVQVG--RPEVLLDGLEPGRDYEVSVQSLR---- 540
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
EA GI P D SH ++ W+ P +
Sbjct 541 ---GPEGSEARGIRARTPTLAPPRHLGFSDVSHDAA----RVFWEGAP--RPVRLVRVTY 591
Query 368 VTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
V+ S NAT T+ + T+ V L ++ LT +A P
Sbjct 592 VSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPS 651
Query 428 MDLKAFPKDNMLWVEW-TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
+ + + W V Y + W L + G + L G L
Sbjct 652 QLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEIS---VPGNLGTAVLPG-L 707
Query 487 AESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVD 545
Y +T+ Y DG S Y P + + + W
Sbjct 708 GRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPP--- 764
Query 546 VQNGFIRNYTIFYRTIIG--NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
G + +Y + Y G E +V+V + + TL L + T Y V ++A G +
Sbjct 765 --LGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEA 822
Query 604 PEFTFTT 610
T T
Sbjct 823 VSATGQT 829
Score = 106 bits (263), Expect = 8e-22, Method: Composition-based stats.
Identities = 77/395 (19%), Positives = 134/395 (34%), Gaps = 40/395 (10%)
Query 225 PHNLSVINSEELSSILKLTWTN-PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P S++ S+ SS ++L+WT P LKY I +R T ++ E A++
Sbjct 378 PAPTSLVLSQVTSSSIRLSWTPAPRHP----LKYLIVWRASRGGTPREVVVEGPAAST-- 431
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+ +L TEY+ + + E G G E G+ P P +
Sbjct 432 -ELHNLASRTEYLVSVFPIYEGGVG------EGLRGLVT-TAPLPPPRALTLAAVT---- 479
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTR----WKSHLQNYTVNATKLTVNLTNDRYLAT 399
RTV L W+ Y V + + + V ++ ++
Sbjct 480 PRTVHLTWQPSAGA------THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYE 533
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
++V++L G + I A P + + V W V+ + +
Sbjct 534 VSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVS 593
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
Q E + G L+ S Y + VT +Y G S + + K+AP
Sbjct 594 SEGGHSG----QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAP- 648
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAVNVDSSHTEYT 578
+ ++ + L W +G + Y I + + G ++V +
Sbjct 649 -SPSQLSMTELPGDAVQLAWV---AAAPSGVLV-YQITWTPLGEGKAHEISVPGNLGTAV 703
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKF 613
L L T Y V + AY +G + P TP
Sbjct 704 LPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPST 738
Score = 81.8 bits (200), Expect = 2e-14, Method: Composition-based stats.
Identities = 49/322 (15%), Positives = 91/322 (28%), Gaps = 22/322 (7%)
Query 315 EEASGITYEDRPSKAPSFWYKIDPSH----TQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
+ G + P+ AP+ P+ +++L W P L Y +
Sbjct 357 QRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHP-----LKYLIVW 411
Query 371 TRWKSHLQNYTV---NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
+ V A ++ R ++V + L P
Sbjct 412 RASRGGTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPR 471
Query 428 MDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
A + + W + + S +P + ++E L L
Sbjct 472 ALTLAAVTPRTVHLTWQPSAGATHYLV----RCSPASPKGEEEEREVQVGRPEVLLDGLE 527
Query 488 ESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
+ Y ++V + I+A P + V + A + W+ P V+
Sbjct 528 PGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDAARVFWEGAPRPVR 585
Query 548 NGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
+ + + G+ + T TL L+S T Y VR+ GG
Sbjct 586 LVRVT----YVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGR 641
Query 608 FTTPKFAQGEIEAIVVPVCLAF 629
TT K ++ A
Sbjct 642 VTTKKAPSPSQLSMTELPGDAV 663
>sp|P29322|EPHA8_HUMAN Ephrin type-A receptor 8 OS=Homo sapiens
OX=9606 GN=EPHA8 PE=1 SV=2
Length=1005
Score = 142 bits (357), Expect = 3e-33, Method: Composition-based stats.
Identities = 54/211 (26%), Positives = 80/211 (38%), Gaps = 18/211 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADC-KAKRDT 178
PP P NL VN G + EW GR + WA + C R
Sbjct 328 PPSAPVNLISSVN-GTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGTRFV 386
Query 179 PTSCTVDYSTVY------FVNIEVWVEAENALGKVTSDHINFDPVYKVK-PNPPHNLSVI 231
P ++ +++ +N W+EA N + ++ + V P + VI
Sbjct 387 PQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVI 446
Query 232 NSEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
E + + L W P + IIL+Y I+Y KD S + + TV LK
Sbjct 447 RQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQS---YSTLKAVTTRATVSGLK 503
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
P T YVF++R G G +S E +G
Sbjct 504 PGTRYVFQVRARTSAGCGRFSQAMEVETGKP 534
Score = 106 bits (265), Expect = 4e-22, Method: Composition-based stats.
Identities = 40/208 (19%), Positives = 73/208 (35%), Gaps = 19/208 (9%)
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITD- 469
AA+ + + ++L + + +EW P + + + + + + P
Sbjct 316 AALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSR 375
Query 470 ----------WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYL 514
Q+ V + L NL Y + V SPE +
Sbjct 376 CEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITT 435
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNVDSS 573
QA PS+ +R ++ G+ L W + + NG I Y I Y ++ + +
Sbjct 436 NQAAPSQVVVIRQERAGQTSVSLLWQE--PEQPNGIILEYEIKYYEKDKEMQSYSTLKAV 493
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
T T+S L T Y+ ++ A T G
Sbjct 494 TTRATVSGLKPGTRYVFQVRARTSAGCG 521
Score = 77.6 bits (189), Expect = 4e-13, Method: Composition-based stats.
Identities = 45/216 (21%), Positives = 74/216 (34%), Gaps = 36/216 (17%)
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV--IILKYNI---------QYR 262
DP PP + S + + L W P I + +
Sbjct 318 LDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCE 377
Query 263 TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS---- 318
+ T + P+ T+ ++S V +L Y F I + SD S E
Sbjct 378 ACGSGT--RFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGV-----SDLSPEPRRAAV 430
Query 319 --GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
T + PS+ + G +V L+W+ P + NG IL+YE+
Sbjct 431 VNITTNQAAPSQ-----VVVIRQERAGQTSVSLLWQE--PEQPNGIILEYEIKYYEKDKE 483
Query 377 LQNYTVN---ATKLTVNLTN--DRYLATLTVRNLVG 407
+Q+Y+ T+ TV+ RY+ + R G
Sbjct 484 MQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAG 519
Score = 69.9 bits (169), Expect = 7e-11, Method: Composition-based stats.
Identities = 39/228 (17%), Positives = 62/228 (27%), Gaps = 32/228 (14%)
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK 374
+S T RP AP ++ + +V L W I Y R
Sbjct 320 PPSSACT---RPPSAP-----VNLISSVNGTSVTLEWAPPLDPGGRSDIT-YNAVCRRCP 370
Query 375 ---------------SHLQNYTVNATKLTVNLTND-RYLATLTVRNLVGK-SDA----AV 413
Q V A+ L NL Y + N V S AV
Sbjct 371 WALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAV 430
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQE 473
+ I + V+ + + + W P E ILE+ + +
Sbjct 431 VNITTNQAAPSQVVVIRQERAGQTSVSLLWQEP-EQPNGIILEYEIKYYEKDKEMQSYST 489
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPS 520
V L Y+ V + G G ++++ + P
Sbjct 490 LKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPR 537
>sp|Q28749|FINC_RABIT Fibronectin (Fragment) OS=Oryctolagus cuniculus
OX=9986 GN=FN1 PE=2 SV=2
Length=2427
Score = 143 bits (359), Expect = 4e-33, Method: Composition-based stats.
Identities = 105/687 (15%), Positives = 190/687 (28%), Gaps = 71/687 (10%)
Query 125 PPEKPKNLSCIVN-EGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSC 182
P P NL N + + W+ + T ++ + SC
Sbjct 1123 PLSPPTNLHLEANPDTGVLTVSWEKSTTPDITGYRITTTPTNGQQGYSLEEVVHADQNSC 1182
Query 183 TV-DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
+ S N+ V+ V D + + P P + + S +
Sbjct 1183 IFENLSPGLEYNVSVY--------TVKDDKESVPVSDTIIPEVPQLTDLSFVDITDSSIG 1234
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
L WT + S I+ Y I I + S+ +TV L+P +Y +
Sbjct 1235 LRWTP--LNSSTIIGYRITVVAAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDYDISVIT 1290
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP-PFEAN 360
+ G+ S + PS P+ + G T+++ W P N
Sbjct 1291 LINGGE------SAPTTLTQQTAVPS--PTDLRFTN----IGPDTMRVTWAPPPSIELTN 1338
Query 361 GKILDYEVTLTRWKSHLQNYT-VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
+ V + L NA LT L YL +++ V + +
Sbjct 1339 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYLVSVS---SVYEQHESTPVRGRQ 1395
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
P + N V WT PR + + W + +
Sbjct 1396 KTGLDAPTGIDFSDVTPNSFTVYWTPPRAPITGF---WIRHHPEHGVGRPREDRVPPSRN 1452
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
+ NL Y++++ + P + + + ++ W
Sbjct 1453 SITLTNLNPGTEYVVSIVALNGREQSPPLIGQ---QSTVSDVPRDLEVIASTPTSLLISW 1509
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
+ V +R Y I Y GN V S + T+S L Y + + A T
Sbjct 1510 EAPAVT-----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGADYTITVYAVTG 1564
Query 598 EGGKDGPE--------------FTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNK 643
G I +P + K
Sbjct 1565 RGDSPASSKPISIDYHTEIDKPSQMQVTDVQDNSISVRWLPSSSPVTGYRVTTT----PK 1620
Query 644 RDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKP 703
PD ++ I P + ++++ +V I + K
Sbjct 1621 NGAGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNRNGESQPLVQTAVTNI--DRPKG 1678
Query 704 FPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVV 763
+D K + +G S ++ S P + + T + +
Sbjct 1679 LAFTDVDVDSIKIAWESPQGQVS----RYRVTYSSPEDGIHELFPAPDGEEDTAEL-QGL 1733
Query 764 HSGYRHQVPSVQVFSRSESTQPLLDSE 790
G + V V + ES QPL+ ++
Sbjct 1734 RPGSEYTVSVVALHDDMES-QPLIGTQ 1759
Score = 131 bits (328), Expect = 2e-29, Method: Composition-based stats.
Identities = 76/502 (15%), Positives = 141/502 (28%), Gaps = 62/502 (12%)
Query 118 ITIISGLPPEKPK--NLSCIVNEGKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKA 174
+ + + PE P+ +LS + + W T + T+ + +
Sbjct 1207 VPVSDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFV 1266
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
+I V + N S V P +L N
Sbjct 1267 DSSVGYYTVTGLEPGIDYDISV-ITLING---GESAPTTLTQQTAVPS--PTDLRFTNIG 1320
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+++TW P S+ + + ++Y + + + ++ + +L P TE
Sbjct 1321 --PDTMRVTWAPP--PSIELTNFLVRYSPVKNE--EDVAELSISPSDNAVVLTNLLPGTE 1374
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGI--TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
Y+ + + E + S G T D P+ ID S + + W
Sbjct 1375 YLVSVSSVYEQHE------STPVRGRQKTGLDAPTG-------IDFSDVTPN-SFTVYWT 1420
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNY------TVNATKLTVNLTNDRYLATLTVRNLV 406
I + + + + N+ LT Y+ ++ N
Sbjct 1421 P-----PRAPITGFWIRHHPEHGVGRPREDRVPPSRNSITLTNLNPGTEYVVSIVALNGR 1475
Query 407 GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
+S + + P L + W P +V+ Y + + +P
Sbjct 1476 EQSPPLIGQQSTV---SDVPRDLEVIASTPTSLLISWEAPAVTVRYYRITYGETGGNSPV 1532
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS----PESIKAYLKQAPPSKG 522
+ T L Y ITV V G P SI + + PS+
Sbjct 1533 Q---EFTVPGSKSTATISGLKPGADYTITVYAVTGRGDSPASSKPISIDYHTEIDKPSQM 1589
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG--NETAVNVDSSHTEYTLS 580
+ V N + W + + Y + G TE T+
Sbjct 1590 ---QVTDVQDNSISVRWLPS-----SSPVTGYRVTTTPKNGAGPTKTKTAGPDQTEMTIE 1641
Query 581 SLTSDTLYMVRMAAYTDEGGKD 602
L Y+V + A G
Sbjct 1642 GLQPTVEYVVSVYAQNRNGESQ 1663
Score = 129 bits (324), Expect = 5e-29, Method: Composition-based stats.
Identities = 75/483 (16%), Positives = 147/483 (30%), Gaps = 62/483 (13%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P + W R + + R
Sbjct 1400 DAPTGIDFSDVTPNSFTVYWTPPRAPIT--------GFWIRHHPEHGVGRPREDRVPPSR 1451
Query 187 STVYFVN------IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
+++ N V + A N G+ S + + P +L VI + L
Sbjct 1452 NSITLTNLNPGTEYVVSIVALN--GREQSPPLI--GQQSTVSDVPRDLEVIA--STPTSL 1505
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
++W P+ V + Y I Y + S + ++S+ T+ LKP +Y +
Sbjct 1506 LISWEAPA---VTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGADYTITVY 1560
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
+ G S T D+PS ++ + Q ++ + W ++
Sbjct 1561 AVTGRGDSPASSKPISIDYHTEIDKPS-------QMQVTDVQDN-SISVRWLP-----SS 1607
Query 361 GKILDYEVTLTRWKSHLQNYTVNA----TKLTVNLTND--RYLATLTVRNLVGKSDAAVL 414
+ Y VT T T A T++T+ Y+ ++ +N G+S V
Sbjct 1608 SPVTGYRVTTTPKNGAGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNRNGESQPLVQ 1667
Query 415 T-IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQE 473
T + D D+ + + + W +P+ V +Y + + S I +
Sbjct 1668 TAVTNIDRPKGLAFTDVDV----DSIKIAWESPQGQVSRYRVTY---SSPEDGIHELFPA 1720
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN 533
T L Y ++V ++ D + ++ +V
Sbjct 1721 PDGEEDTAELQGLRPGSEYTVSVVALHDD---MESQPLIGTQSTAIPAPTNLKFTQVTPT 1777
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFY--RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
+W N + Y + + G +N+ + +S L T Y V
Sbjct 1778 SLSAQWTPP-----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1832
Query 592 MAA 594
+ A
Sbjct 1833 VYA 1835
Score = 127 bits (319), Expect = 2e-28, Method: Composition-based stats.
Identities = 69/477 (14%), Positives = 143/477 (30%), Gaps = 53/477 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+KP + + + W T + K K P +
Sbjct 1584 DKPSQMQVTDVQDNSISVRWLPSSSPVTGYRVTT---TPKNGAGPTKTKTAGPDQTEMTI 1640
Query 187 S-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
V V V A+N G+ + +P + ++ +K+ W
Sbjct 1641 EGLQPTVEYVVSVYAQNRNGESQ-PLVQTAVTNIDRPK-----GLAFTDVDVDSIKIAWE 1694
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
+P + +Y + Y + + P D +Q L+P +EY + + +D
Sbjct 1695 SPQ---GQVSRYRVTYSSPEDGIHELFPAPDGEEDT--AELQGLRPGSEYTVSVVALHDD 1749
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
+ S+ G P+ + ++ P+ ++ W N ++
Sbjct 1750 ME------SQPLIGTQSTAIPAPTNLKFTQVTPT------SLSAQWTP-----PNVQLTG 1792
Query 366 YEVTLTRWKSHLQNYTVN------ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
Y V +T + +N + ++ + +Y ++ S I
Sbjct 1793 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPVQGVITTL 1852
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ + + + + + W T E++ + ++ + + P Q+ R
Sbjct 1853 ENVSPPRRARVTD-ATETTITISWRTKTETITGFRVDAIPANGQNP----IQRIIKPDVR 1907
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
+Y L Y I + + + SP I A PS + N ++ W
Sbjct 1908 SYTITGLQPGTDYKIHLYTLNDNAQSSPVIIDASTAIDAPS---NLHFLATTPNSLLVSW 1964
Query 540 DQLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
I Y I + E TE T++ L T Y + + A
Sbjct 1965 QPPRAK-----ITGYIIKFEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYIIA 2016
Score = 126 bits (317), Expect = 3e-28, Method: Composition-based stats.
Identities = 69/529 (13%), Positives = 153/529 (29%), Gaps = 55/529 (10%)
Query 80 TIINRTASSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNE 138
+ + +S+T T++ ++ L + + G + P++L I +
Sbjct 1445 DRVPPSRNSITLTNLNPGTEYVVSIVALNGREQSPPLIG---QQSTVSDVPRDLEVIAST 1501
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
+ W+ T T + S + + V
Sbjct 1502 PTSLLISWEAPAVTVRYYRIT--YGETGGNSPVQEFTVPGSKSTATISGLKPGADYTITV 1559
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A G + Y + + P + V + ++ S + + W S + Y
Sbjct 1560 YAVTGRGDSPASSKPISIDYHTEIDKPSQMQVTDVQDNS--ISVRWLP---SSSPVTGYR 1614
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA- 317
+ K+ + ++ ++ T++ L+P EYV + +G+ S+
Sbjct 1615 VTTTPKNGAGPTKTKTAG--PDQTEMTIEGLQPTVEYVVSVYAQNRNGE------SQPLV 1666
Query 318 -SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
+ +T DRP +D ++++ W+ G++ Y VT + +
Sbjct 1667 QTAVTNIDRPKGLAFTDVDVD--------SIKIAWE-----SPQGQVSRYRVTYSSPEDG 1713
Query 377 LQNYT------VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
+ + +L Y ++ + +S + A +L
Sbjct 1714 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQP----LIGTQSTAIPAPTNL 1769
Query 431 K-AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
K L +WT P + Y + V + + G L +
Sbjct 1770 KFTQVTPTSLSAQWTPPNVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSG-LMVA 1826
Query 490 KCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y ++V + P + S R + + W +
Sbjct 1827 TKYEVSVYALKDTLTSRPVQGVITTLENV-SPPRRARVTDATETTITISWR-TKTET--- 1881
Query 550 FIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
I + + N + YT++ L T Y + + D
Sbjct 1882 -ITGFRVDAIPANGQNPIQRIIKPDVRSYTITGLQPGTDYKIHLYTLND 1929
Score = 124 bits (311), Expect = 2e-27, Method: Composition-based stats.
Identities = 88/506 (17%), Positives = 160/506 (32%), Gaps = 54/506 (11%)
Query 138 EGKKMRCEWDGGRET--HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN-I 194
W +T + L E K+ D + + + Y VN
Sbjct 682 TASSFVVSWVSASDTVSGFLVEYELSEEGDEPKYLDLPSTVTSVNIPDLLPGRKYIVNVY 741
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
++ E + +L TS P+ P + +V ++ S + + W+ P I
Sbjct 742 QISEEGKQSLILSTSQTT--------APDAPPDPTVDQVDDTS--IVVRWSRPQAP---I 788
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
Y + Y + +++ + T +S T+ DL+P +Y I ++E+ +
Sbjct 789 TGYRVVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNITIYAVEENQESAPVFIQ 845
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK 374
+E +G+ D P ++ + + V ++W + + Y V +
Sbjct 846 QETTGVPRSDE-VPPPKDLQFVEVTDVK----VTIMWTP-----PDSAVTGYRVDVLPVH 895
Query 375 SHLQN-----YTVNA-TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+N + N ++T Y + N +S + A
Sbjct 896 LPGENGQRLPVSRNTFAEITGLSPGVTYYFKVFAVNHGRESRP----LTAQQATKLDAPT 951
Query 429 DLK-AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
+L+ D+ + V WT PR + Y L P Q G YL NL
Sbjct 952 NLQFVNETDSSVLVIWTPPRARITGYQLTIGPTRGGQPK----QHNVGPTVSKYLLRNLQ 1007
Query 488 ESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
Y +T+ V + + Q S P +V + V+ W P
Sbjct 1008 PGSEYTVTLIAVKGNNQSPKVTGVFTTLQPQSSIPPYST--EVTETSIVITWTPAPR--- 1062
Query 548 NGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF- 606
+ + R G E V S +S LT Y+ + D +D P
Sbjct 1063 ----IGFKLGVRPSQGGEAPREVTSESGSIVVSGLTPGVEYVYSIQVLRDGKERDAPIVN 1118
Query 607 TFTTPKFAQGEIEAIVVPVCLAFLLT 632
T TP + P ++
Sbjct 1119 TVVTPLSPPTNLHLEANPDTGVLTVS 1144
Score = 116 bits (290), Expect = 5e-25, Method: Composition-based stats.
Identities = 93/554 (17%), Positives = 174/554 (31%), Gaps = 68/554 (12%)
Query 85 TASSVTFTDIA-SLNIQLTCNILTFGQLEQNVY------GITIISGLPPEKPKNLSCIVN 137
TA+SVT +D+ + +T + Q V+ G+ +PP PK+L +
Sbjct 811 TANSVTLSDLQPGVQYNITIYAVEENQESAPVFIQQETTGVPRSDEVPP--PKDLQFVEV 868
Query 138 EGKKMRCEWDG--GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIE 195
K+ W T + L R+T T V
Sbjct 869 TDVKVTIMWTPPDSAVTGYRVD-VLPVHLPGENGQRLPVSRNTFAEITGLSPGV---TYY 924
Query 196 VWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
V A N G+ + K + P NL E S + + WT P + I
Sbjct 925 FKVFAVNH-GRESRP---LTAQQATKLDAPTNLQ--FVNETDSSVLVIWTPPRAR---IT 975
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y + Q T S + +++L+P +EY + +K + + S
Sbjct 976 GYQLTIGPTRGGQPKQHNVGPTVSK---YLLRNLQPGSEYTVTLIAVKGNNQ------SP 1026
Query 316 EASG--ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
+ +G T + + S P S ++ + W P + +++ +
Sbjct 1027 KVTGVFTTLQPQSSIPP-------YSTEVTETSIVITWTPAPR-------IGFKLGVRPS 1072
Query 374 KSHLQNYTVNATK----LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMD 429
+ V + ++ Y+ ++ V GK A + + +
Sbjct 1073 QGGEAPREVTSESGSIVVSGLTPGVEYVYSIQVLRD-GKERDAPIVNTVVTPLSPPTNLH 1131
Query 430 LKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW--QQEDGTVHRTYLRGNLA 487
L+A P +L V W +S I + + + + ++ + + NL+
Sbjct 1132 LEANPDTGVLTVSWE---KSTTPDITGYRITTTPTNGQQGYSLEEVVHADQNSCIFENLS 1188
Query 488 ESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
Y ++V V D P S + + + + + L W L
Sbjct 1189 PGLEYNVSVYTVKDDKESVPVSDTIIPE---VPQLTDLSFVDITDSSIGLRWTPL----N 1241
Query 548 NGFIRNYTIFYRTIIG--NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ I Y I VDSS YT++ L Y + + + G
Sbjct 1242 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1301
Query 606 FTFTTPKFAQGEIE 619
T T + ++
Sbjct 1302 LTQQTAVPSPTDLR 1315
Score = 110 bits (274), Expect = 4e-23, Method: Composition-based stats.
Identities = 50/391 (13%), Positives = 125/391 (32%), Gaps = 35/391 (9%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + + + + + W P I KY +++R K++ + +S+
Sbjct 561 PVQVIITETPSQPNSHPIQWNAPEPSH--ISKYILRWRPKNSVG--RWKEATIPGHLNSY 616
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSD---------WSEEASGITYEDRPSKAPSFWYK 335
T++ L+P Y ++ +++ G + ++ +T E P
Sbjct 617 TIKGLRPGVMYEGQLISIQQYGHREVTRFDFTTTSTSTPVTSNTVTGETTPLSP--VVAT 674
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR 395
+ + + W + + G +++YE++ + + T + +
Sbjct 675 SESVTEITASSFVVSWVSASDTVS-GFLVEYELSEEGDEPKYLDLPSTVTSVNIPDLLPG 733
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL 455
+ V + + +++ + P D + V W+ P+ + Y +
Sbjct 734 RKYIVNVYQISEEGKQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRV 793
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA--- 512
+ S + T + L +L Y IT+ V + +P I+
Sbjct 794 VY---SPSVEGSSTELNLPETANSVTL-SDLQPGVQYNITIYAVEENQESAPVFIQQETT 849
Query 513 ---YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI--IGNETA 567
+ PP ++ +V + + W + + Y + + G
Sbjct 850 GVPRSDEVPP--PKDLQFVEVTDVKVTIMWTPP-----DSAVTGYRVDVLPVHLPGENGQ 902
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
S +T ++ L+ Y ++ A
Sbjct 903 RLPVSRNTFAEITGLSPGVTYYFKVFAVNHG 933
Score = 88.4 bits (217), Expect = 2e-16, Method: Composition-based stats.
Identities = 61/397 (15%), Positives = 110/397 (28%), Gaps = 39/397 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
++PK L+ + ++ W+ + + + + D
Sbjct 1674 DRPKGLAFTDVDVDSIKIAWE--SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ 1731
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V V A + + S + P P NL + L WT
Sbjct 1732 GLRPGSEYTVSVVALHD--DMESQPL-IGTQSTAIP-APTNLKFTQV--TPTSLSAQWTP 1785
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P +V + Y ++ K+ + + A SS V L T+Y + +K+
Sbjct 1786 P---NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1840
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
S G+ P D + T T+ + W+T I +
Sbjct 1841 T------SRPVQGVITTLENVSPPRRARVTDATET----TITISWRTKTET-----ITGF 1885
Query 367 EVTLTRWKSHLQNY-----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
V V + +T Y L N +S ++
Sbjct 1886 RVDAIPANGQNPIQRIIKPDVRSYTITGLQPGTDYKIHLYTLNDNAQSSPVIIDASTAI- 1944
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
P N L V W PR + YI+++ +P + V
Sbjct 1945 --DAPSNLHFLATTPNSLLVSWQPPRAKITGYIIKFE--KPGSPPREVVPRPRPGVTEAT 2000
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ G L Y I + + + P + + P
Sbjct 2001 ITG-LEPGTEYTIYIIALKNNQKSDPLIGRKKTDELP 2036
Score = 54.5 bits (129), Expect = 5e-06, Method: Composition-based stats.
Identities = 54/334 (16%), Positives = 107/334 (32%), Gaps = 37/334 (11%)
Query 501 ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G + ++ Y + P + + N ++W+ I Y + +R
Sbjct 543 GIGEWHCQPLQTYPGTSGPVQVI-ITETPSQPNSHPIQWNAPEPSH----ISKYILRWRP 597
Query 561 I--IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF---------- 608
+G + YT+ L +Y ++ + G ++ F F
Sbjct 598 KNSVGRWKEATIPGHLNSYTIKGLRPGVMYEGQLISIQQYGHREVTRFDFTTTSTSTPVT 657
Query 609 -------TTP-------KFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPN 654
TTP + EI A V T+ G L + + + + +
Sbjct 658 SNTVTGETTPLSPVVATSESVTEITASSFVVSWVSASDTVSGFLVEYELSEEGDEPKYLD 717
Query 655 VPDPSKS-HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPF---PEDLKS 710
+P S +I P N + S P +D
Sbjct 718 LPSTVTSVNIPDLLPGRKYIVNVYQISEEGKQSLILSTSQTTAPDAPPDPTVDQVDDTSI 777
Query 711 LDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQ 770
+ + + + G+ S SS+ ++ + + + + VQY+ +++ +Q
Sbjct 778 VVRWSRPQAPITGYRVVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQ 837
Query 771 VPSVQVFSRSESTQ-PLLDSEERPEDLQLVDHVD 803
+ VF + E+T P D P+DLQ V+ D
Sbjct 838 ESAP-VFIQQETTGVPRSDEVPPPKDLQFVEVTD 870
>sp|Q80Z71|TENN_MOUSE Tenascin-N OS=Mus musculus OX=10090 GN=Tnn
PE=1 SV=2
Length=1560
Score = 142 bits (358), Expect = 4e-33, Method: Composition-based stats.
Identities = 80/475 (17%), Positives = 156/475 (33%), Gaps = 57/475 (12%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
P+ L + + + W+ E ++ L S + K + P
Sbjct 264 APQGLQLLKSTENSLLVSWEPSSE----VDYYLLSYYPLGK-EQATKQVRVPKEQHTYDI 318
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS----EELSSILKLT 243
T + V N ++S + +L+V+ + EE + L +
Sbjct 319 TGLLPGTKYIVTLRNVKKDISSSPQHLLAT--------TDLAVVGTAWVNEETETSLDVE 370
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
W NP + + Y ++Y +++ + +S + + L+P TEY + ++
Sbjct 371 WENPLTE---VDYYKLRYGPLTGQEVTEVTVPKSRDPKSRYDITGLQPGTEYKITVVPIR 427
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
D +G +G T D P+ ++ T + W + + + +
Sbjct 428 GDLEGKP----ILLNGRTEIDGPTN--------VVTNQVTEDTASVSWDPVR-ADIDKYV 474
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTV-RNLVGKSDAAVLTIPACDFQ 422
+ Y K ++T LT + Y + R G A + D
Sbjct 475 VRYIAPDGETKEKAVPKDQSSTVLTGLKPGEAYKVFVWAERGNQGSKKADTKALTEID-- 532
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
P + +N L V W + +Y++ + D +++ R+ +
Sbjct 533 --SPENLVTDRVTENSLSVSWDPVEADIDRYVVSY-TSVDGETKQVPVKKD----QRSTV 585
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS---KGPTVRTKKVGKNEAVLEW 539
L+ Y + V D ES KA K P+ + T +V +N + W
Sbjct 586 LTGLSPGVEYKVYVWAEKGD----RESKKANTK--APTDIDSPKNLVTDQVTENTLSVSW 639
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
D + + I Y + Y + G V V + L+ L Y V + A
Sbjct 640 DPVQAN-----IDRYMVSYTSADGETREVPVPKEKSSTVLTGLRPGVEYKVHVWA 689
Score = 130 bits (327), Expect = 2e-29, Method: Composition-based stats.
Identities = 90/520 (17%), Positives = 157/520 (30%), Gaps = 68/520 (13%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P N+ WD R + ++ + + +D ++
Sbjct 444 DGPTNVVTNQVTEDTASVSWDPVRADI--DKYVVRYIAPDGETKEKAVPKDQSSTVLTGL 501
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ VW E N G +D + + P NL E S L ++W
Sbjct 502 KPGEAYKVFVWAERGNQ-GSKKADTKALTEI-----DSPENLVTDRVTENS--LSVSWDP 553
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
I +Y + Y + D T + S + L P EY +
Sbjct 554 ---VEADIDRYVVSYTSVDGET----KQVPVKKDQRSTVLTGLSPGVEYKVYV------- 599
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKID-PSHTQGYRTVQLVWKTLPPFEANGKILD 365
W+E+ + + + + T+ + W + +AN I
Sbjct 600 ------WAEKGDRESKKANTKAPTDIDSPKNLVTDQVTENTLSVSWDPV---QAN--IDR 648
Query 366 YEVTLTRWKSHLQNYTV----NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
Y V+ T + V ++T LT Y + + +S A P
Sbjct 649 YMVSYTSADGETREVPVPKEKSSTVLTGLRPGVEYKVHVWAQKGTQESRKANTKAPTDI- 707
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
P + + L V W + +Y++ + T T
Sbjct 708 --DGPKNLVTDQVTETTLSVSWDPVEADIDRYMVRY----TSPDGETKEVPVSKDKSSTV 761
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS---KGPTVRTKKVGKNEAVLE 538
LRG L Y + V G+ +S KA K P+ + T++V ++ A +
Sbjct 762 LRG-LRPGVEYKVDV----WAQKGAQDSRKANTK--APTDIDSPKNLVTEQVTESTATVS 814
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
WD + D I Y + Y ++ G V T L+ + Y V + A
Sbjct 815 WDPVEAD-----IDRYVVRYTSVDGETREFLVGKDQTSTVLTGMRPGVEYQVDVWAQ--- 866
Query 599 GGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
G + + T A +I+ V TTL
Sbjct 867 ---KGTQESRKTSTKAPTDIDGPKNLVTDQVTETTLSVSW 903
Score = 128 bits (322), Expect = 7e-29, Method: Composition-based stats.
Identities = 83/492 (17%), Positives = 149/492 (30%), Gaps = 60/492 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P+NL + WD E ++ + + + K+D TV
Sbjct 532 DSPENLVTDRVTENSLSVSWDP-VEADID-RYVVSYTSVDGETKQVPVKKDQ--RSTVLT 587
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V +V+V AE + + P + P NL E L ++W
Sbjct 588 GLSPGVEYKVYVWAEKGDRESKKANTKA-PTDI---DSPKNLVTDQVTEN--TLSVSWDP 641
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
I +Y + Y + D T P++ +ST + L+P EY +
Sbjct 642 VQAN---IDRYMVSYTSADGETREVPVPKEKSST----VLTGLRPGVEYKVHV------- 687
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKID-PSHTQGYRTVQLVWKTLPPFEANGKILD 365
W+++ + + + + + T+ + W + I
Sbjct 688 ------WAQKGTQESRKANTKAPTDIDGPKNLVTDQVTETTLSVSWDPV-----EADIDR 736
Query 366 YEVTLTRWKSHLQNYTV----NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
Y V T + V ++T L Y + + S A P
Sbjct 737 YMVRYTSPDGETKEVPVSKDKSSTVLRGLRPGVEYKVDVWAQKGAQDSRKANTKAPTDI- 795
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
P + ++ V W + +Y++ + + + T
Sbjct 796 --DSPKNLVTEQVTESTATVSWDPVEADIDRYVVRYTSVDGETREFL----VGKDQTSTV 849
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWD 540
L G + Y + V G+ ES K K GP + T +V + + WD
Sbjct 850 LTG-MRPGVEYQVDV----WAQKGTQESRKTSTKAPTDIDGPKNLVTDQVTETTLSVSWD 904
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
+ D I Y + Y + G V V + L L Y V + A +G
Sbjct 905 PVEAD-----IDRYMVRYTSPDGETKEVPVSKDKSSTVLRGLRPGVEYKVDVWAQ--KGA 957
Query 601 KDGPEFTFTTPK 612
+D + P
Sbjct 958 QDSRKANTKAPT 969
Score = 128 bits (322), Expect = 8e-29, Method: Composition-based stats.
Identities = 75/476 (16%), Positives = 150/476 (32%), Gaps = 62/476 (13%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ PKNL WD E ++ + ++ + + +D ++
Sbjct 796 DSPKNLVTEQVTESTATVSWDP-VEADID-RYVVRYTSVDGETREFLVGKDQTSTVLTGM 853
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
++VW + + TS D P NL E + L ++W
Sbjct 854 RPGVEYQVDVWAQKGTQESRKTSTKAPTDIDG------PKNLVTDQVTE--TTLSVSWDP 905
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
I +Y ++Y + D T + +SS ++ L+P EY +
Sbjct 906 ---VEADIDRYMVRYTSPDGET----KEVPVSKDKSSTVLRGLRPGVEYKVDV------- 951
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS-HTQGYRTVQLVWKTLPPFEANGKILD 365
W+++ + + + + + T+ + W + I
Sbjct 952 ------WAQKGAQDSRKANTKAPTDIDSPKNLAIDQVTETTLSVSWDPV-----QADIDR 1000
Query 366 YEVTLTRWKSHLQNYTV----NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
Y V T + + + +T LT Y + + +S A
Sbjct 1001 YVVRYTSADGESKEFLIGKEQRSTVLTGLRPGVEYKVEVWAQKGARESKKANTEGHTDI- 1059
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
P + +N + W + + +Y++ + + I +++ TV
Sbjct 1060 --DSPKNLVTNQVTENTATISWDPVQADIDRYMVRYTSADGETREIPVRKEKSSTV---- 1113
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS---KGPTVRTKKVGKNEAVLE 538
L Y + V G+ ES KA K P+ + T +V +N A +
Sbjct 1114 -LTGLRPGVEYTVQV----WAQKGARESKKAKTK--APTEIDSPKNLVTNRVTENTATIS 1166
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
WD + + I Y + Y + G + V + L+ L Y + + A
Sbjct 1167 WDPVRAN-----IDRYMVRYTSADGETKEIPVSKDQSSTILTGLKPGMEYTIHVWA 1217
Score = 124 bits (312), Expect = 1e-27, Method: Composition-based stats.
Identities = 79/477 (17%), Positives = 142/477 (30%), Gaps = 64/477 (13%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGR--ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
+ PKNL + WD + ++T ++ T + S TV
Sbjct 620 DSPKNLVTDQVTENTLSVSWDPVQANIDRYMVSYT-SADGETREVP-----VPKEKSSTV 673
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
V +V V A+ + + P P +++ + + L ++W
Sbjct 674 LTGLRPGVEYKVHVWAQKG-TQESRKANTKAPTDIDGPK-----NLVTDQVTETTLSVSW 727
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
I +Y ++Y + D T + +SS ++ L+P EY +
Sbjct 728 DP---VEADIDRYMVRYTSPDGET----KEVPVSKDKSSTVLRGLRPGVEYKVDV----- 775
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
W+ + S P+ S + + T + W + I
Sbjct 776 -----WAQKGAQDSRKANTKAPTDIDSPKNLV--TEQVTESTATVSWDPV-----EADID 823
Query 365 DYEVTLTRWKSHLQNYTV----NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
Y V T + + V +T LT Y + + +S P
Sbjct 824 RYVVRYTSVDGETREFLVGKDQTSTVLTGMRPGVEYQVDVWAQKGTQESRKTSTKAPTDI 883
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
P + + L V W + +Y++ + T T
Sbjct 884 ---DGPKNLVTDQVTETTLSVSWDPVEADIDRYMVRY----TSPDGETKEVPVSKDKSST 936
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS---KGPTVRTKKVGKNEAVL 537
LRG L Y + V G+ +S KA K P+ + +V + +
Sbjct 937 VLRG-LRPGVEYKVDV----WAQKGAQDSRKANTK--APTDIDSPKNLAIDQVTETTLSV 989
Query 538 EWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
WD + D I Y + Y + G + L+ L Y V + A
Sbjct 990 SWDPVQAD-----IDRYVVRYTSADGESKEFLIGKEQRSTVLTGLRPGVEYKVEVWA 1041
Score = 121 bits (304), Expect = 1e-26, Method: Composition-based stats.
Identities = 85/497 (17%), Positives = 157/497 (32%), Gaps = 58/497 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ PKNL + WD E ++ + ++ + + +D S TV
Sbjct 884 DGPKNLVTDQVTETTLSVSWDP-VEADID-RYMVRYTSPDGETKEVPVSKD--KSSTVLR 939
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V +V V A+ K D + + P NL++ E + L ++W
Sbjct 940 GLRPGVEYKVDVWAQ----KGAQDSRKANTKAPTDIDSPKNLAIDQVTE--TTLSVSWDP 993
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
I +Y ++Y + D + + ++ + S + L+P EY +
Sbjct 994 ---VQADIDRYVVRYTSADGESKEFLIGKE----QRSTVLTGLRPGVEYKVEV------- 1039
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKID-PSHTQGYRTVQLVWKTLPPFEANGKILD 365
W+++ + + + + ++ T + W + I
Sbjct 1040 ------WAQKGARESKKANTEGHTDIDSPKNLVTNQVTENTATISWDPV-----QADIDR 1088
Query 366 YEVTLTRWKSHLQNYTV----NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
Y V T + V ++T LT Y + + +S A P
Sbjct 1089 YMVRYTSADGETREIPVRKEKSSTVLTGLRPGVEYTVQVWAQKGARESKKAKTKAPT--- 1145
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
+ P + +N + W R ++ +Y++ + + I + + T
Sbjct 1146 EIDSPKNLVTNRVTENTATISWDPVRANIDRYMVRYTSADGETKEIPVSKDQSST----- 1200
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWD 540
+ L Y I V G+ ES KA K P +R V + VL W
Sbjct 1201 ILTGLKPGMEYTIHV----WAQKGARESKKADTKALTEIDPPRNLRPFGVTHSGGVLTW- 1255
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
LP Q I Y + Y+ G V + + L L Y V + A+
Sbjct 1256 -LPPSAQ---IDGYILTYQFPNGTVKEVELPRGQQRFELQDLEQGVTYPVSLVAFKGNQR 1311
Query 601 KDGPEFTFTTPKFAQGE 617
T +T
Sbjct 1312 SRTVSTTLSTVDARFPH 1328
Score = 116 bits (291), Expect = 4e-25, Method: Composition-based stats.
Identities = 83/481 (17%), Positives = 147/481 (31%), Gaps = 56/481 (12%)
Query 138 EGKKMRCEWDGGRETHLETNFTLKSEWATHKFAD-CKAKRDTPTSCTVDYSTVYFVNIEV 196
+ EW+ T ++ + + K P S ++
Sbjct 363 TETSLDVEWENPL-TEVDYYKLRYGPLTGQEVTEVTVPKSRDPKSRYDITGLQPGTEYKI 421
Query 197 WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK 256
V G + I + + + + P N V+ ++ ++W I K
Sbjct 422 TVVPIR--GDLEGKPILLN--GRTEIDGPTN--VVTNQVTEDTASVSWDP---VRADIDK 472
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y ++Y D T + P+D +SS + LKP Y + + + +D
Sbjct 473 YVVRYIAPDGETKEKAVPKD----QSSTVLTGLKPGEAYKVFVWAERGNQGSKKAD---- 524
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
+T D P + ++ + W + I Y V+ T
Sbjct 525 TKALTEIDSPENL--------VTDRVTENSLSVSWDPV-----EADIDRYVVSYTSVDGE 571
Query 377 LQNYTVN----ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA 432
+ V +T LT Y + +S A P P +
Sbjct 572 TKQVPVKKDQRSTVLTGLSPGVEYKVYVWAEKGDRESKKANTKAPTDI---DSPKNLVTD 628
Query 433 FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
+N L V W + ++ +Y++ + + + T L G L Y
Sbjct 629 QVTENTLSVSWDPVQANIDRYMVSYTSADGETREVP----VPKEKSSTVLTG-LRPGVEY 683
Query 493 LITVTPVYADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
+ V G+ ES KA K GP + T +V + + WD + D I
Sbjct 684 KVHV----WAQKGTQESRKANTKAPTDIDGPKNLVTDQVTETTLSVSWDPVEAD-----I 734
Query 552 RNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP 611
Y + Y + G V V + L L Y V + A +G +D + P
Sbjct 735 DRYMVRYTSPDGETKEVPVSKDKSSTVLRGLRPGVEYKVDVWAQ--KGAQDSRKANTKAP 792
Query 612 K 612
Sbjct 793 T 793
Score = 67.2 bits (162), Expect = 7e-10, Method: Composition-based stats.
Identities = 53/316 (17%), Positives = 92/316 (29%), Gaps = 38/316 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ PKNL WD + + ++ A + + +++ S TV
Sbjct 1060 DSPKNLVTNQVTENTATISWDPVQADI--DRYMVRYTSADGETREIPVRKE--KSSTVLT 1115
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V V V A+ + P + P NL E ++ + +W
Sbjct 1116 GLRPGVEYTVQVWAQKGARESKKAKTKA-PTEI---DSPKNLVTNRVTENTATI--SWDP 1169
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
I +Y ++Y + D T + +SS + LKP EY + K
Sbjct 1170 VRAN---IDRYMVRYTSADGET----KEIPVSKDQSSTILTGLKPGMEYTIHVWAQKGAR 1222
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
E T P +H+ G L W LPP I Y
Sbjct 1223 --------ESKKADTKALTEIDPPRNLRPFGVTHSGG----VLTW--LPPSAQ---IDGY 1265
Query 367 EVTLTRWKSHLQNY--TVNATKLTVNLTNDRYLATLTVRNLVG--KSDAAVLTIPACDFQ 422
+T ++ + + +++ G +S T+ D +
Sbjct 1266 ILTYQFPNGTVKEVELPRGQQRFELQDLEQGVTYPVSLVAFKGNQRSRTVSTTLSTVDAR 1325
Query 423 ATHPVMDLKAFPKDNM 438
HP + N
Sbjct 1326 FPHPSDCSQVQQNTNA 1341
>sp|Q61772|EPHA7_MOUSE Ephrin type-A receptor 7 OS=Mus musculus
OX=10090 GN=Epha7 PE=1 SV=2
Length=998
Score = 141 bits (356), Expect = 4e-33, Method: Composition-based stats.
Identities = 50/215 (23%), Positives = 81/215 (38%), Gaps = 21/215 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADCKAK---R 176
PP P+NL +N+ + EW GR + W + C +
Sbjct 331 PPSAPQNLIFNINQ-TTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYM 389
Query 177 DTPTSCTVDYSTVY----FVNIEVWVEAENALGKVTSDHINFDPVYKV--KPNPPHNLSV 230
T +Y TV N VEA N + ++ F V + P V
Sbjct 390 PQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGV 449
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ L ++L+W P + +I +Y I+Y KD + + +S ++ +LK
Sbjct 450 MKERVLQRSVQLSWQEPEHPNGVITEYEIKYYEKD---QRERTYSTLKTKSTSASINNLK 506
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
P T YVF+IR + G G ++S T E+
Sbjct 507 PGTVYVFQIRAVTAAGYG---NYSPRLDVATLEEA 538
Score = 105 bits (262), Expect = 7e-22, Method: Composition-based stats.
Identities = 44/213 (21%), Positives = 72/213 (34%), Gaps = 20/213 (9%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTP-----RESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
+L + +EW+ P R V IL ++ C+
Sbjct 331 PPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMP 390
Query 478 HRTYLRGN------LAESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTVR 526
+T L N L Y V V S + QA PS+ V
Sbjct 391 QQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVM 450
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSD 585
++V + L W + + NG I Y I Y E T + + T ++++L
Sbjct 451 KERVLQRSVQLSWQE--PEHPNGVITEYEIKYYEKDQRERTYSTLKTKSTSASINNLKPG 508
Query 586 TLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGE 617
T+Y+ ++ A T G + P T + A G+
Sbjct 509 TVYVFQIRAVTAAGYGNYSPRLDVATLEEASGK 541
Score = 79.5 bits (194), Expect = 1e-13, Method: Composition-based stats.
Identities = 44/246 (18%), Positives = 78/246 (32%), Gaps = 27/246 (11%)
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII-LKYNIQYRTK 264
+ SD P+ P NL + + L W+ P+ + Y I +
Sbjct 318 RAPSDPPYVACTR--PPSAPQNLIF---NINQTTVSLEWSPPADNGGRNDVTYRILCKRC 372
Query 265 DASTWSQIP--------PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW-SE 315
+P P+ T + TV DL Y F + + S
Sbjct 373 SWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFA 432
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
S T + PS+ + R+VQL W+ P NG I +YE+
Sbjct 433 AVSITTGQAAPSQVSGVMKERVLQ-----RSVQLSWQE--PEHPNGVITEYEIKYYEKDQ 485
Query 376 HLQNYT---VNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
+ Y+ +T ++N Y+ + G + + A +A+ + +
Sbjct 486 RERTYSTLKTKSTSASINNLKPGTVYVFQIRAVTAAGYGNYSPRLDVATLEEASGKMFEA 545
Query 431 KAFPKD 436
A +
Sbjct 546 TAVSSE 551
>sp|O42422|EPHA7_CHICK Ephrin type-A receptor 7 OS=Gallus gallus
OX=9031 GN=EPHA7 PE=2 SV=1
Length=993
Score = 141 bits (355), Expect = 5e-33, Method: Composition-based stats.
Identities = 51/219 (23%), Positives = 82/219 (37%), Gaps = 21/219 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADCKAK---R 176
PP P+NL +N+ + EW GR + W + C +
Sbjct 331 PPSAPQNLIFNINQ-TTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYM 389
Query 177 DTPTSCTVDYSTVY----FVNIEVWVEAENALGKVTSDHINFDPVYKV--KPNPPHNLSV 230
T +Y TV N VEA N + ++ F V + P V
Sbjct 390 PQQTGLVDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGV 449
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ L ++L+W P + +I +Y I+Y KD + + +S ++ +LK
Sbjct 450 MKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKD---QRERTYSTVKTKSTSASINNLK 506
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
P T YVF+IR G G ++S T E+ + A
Sbjct 507 PGTVYVFQIRAFTAAGYG---NYSPRLDVATLEEATATA 542
Score = 106 bits (263), Expect = 6e-22, Method: Composition-based stats.
Identities = 41/212 (19%), Positives = 73/212 (34%), Gaps = 20/212 (9%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDK-----------APCITDWQ 471
+L + +EW+ P ++ + + + +L + I
Sbjct 331 PPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMP 390
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTVR 526
Q+ G V +L Y V V S + QA PS+ V
Sbjct 391 QQTGLVDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVM 450
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSD 585
++V + L W + + NG I Y I Y E T V + T ++++L
Sbjct 451 KERVLQRSVELSWQE--PEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKPG 508
Query 586 TLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQG 616
T+Y+ ++ A+T G + P T + A
Sbjct 509 TVYVFQIRAFTAAGYGNYSPRLDVATLEEATA 540
Score = 77.2 bits (188), Expect = 5e-13, Method: Composition-based stats.
Identities = 42/243 (17%), Positives = 75/243 (31%), Gaps = 28/243 (12%)
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII-LKYNIQYRTK 264
+ SD P+ P NL + + L W+ P+ + Y I +
Sbjct 318 RAPSDPPYVACTR--PPSAPQNLIF---NINQTTVSLEWSPPADNGGRNDVTYRILCKRC 372
Query 265 DASTWSQIP--------PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW-SE 315
+P P+ T + TV DL Y F + + S
Sbjct 373 SWEQGECVPCGSNIGYMPQQTGLVDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFA 432
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
S T + PS+ + R+V+L W+ P NG I +YE+
Sbjct 433 AVSITTGQAAPSQVSGVMKERVLQ-----RSVELSWQE--PEHPNGVITEYEIKYYEKDQ 485
Query 376 HLQNYT---VNATKLTVNLTN--DRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMD 429
+ Y+ +T ++N Y+ + G + + L + + V
Sbjct 486 RERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATATAVSS 545
Query 430 LKA 432
+
Sbjct 546 EQN 548
>sp|Q91740|FINC_XENLA Fibronectin OS=Xenopus laevis OX=8355 GN=fn1
PE=2 SV=1
Length=2481
Score = 142 bits (357), Expect = 6e-33, Method: Composition-based stats.
Identities = 71/490 (14%), Positives = 145/490 (30%), Gaps = 39/490 (8%)
Query 125 PPEKPKNLSCI-VNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P P NL + + WD + T + + + + + + P+
Sbjct 1173 PLSPPTNLRLQPSRDSATLTVYWDRSISPGI-TGYRISTTPTPMQVGNSLEEEVGPSQTY 1231
Query 184 VDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
+ + V V V A + S ++ + ++ P + + + + L
Sbjct 1232 CVFENLSPGVEYNVSVYAVKE--EEESAPLSQMFLQEI----PQLTDIKYDDVTDTSIDL 1285
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
WT + S I+ Y I S I E T + V L+P +Y + +
Sbjct 1286 RWTP--LNSSNIIGYRITVVAAGESV--PIYEEFVGPTDGYYKVSGLEPGIDYEISLITL 1341
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
G+ S + I + P P+ + G +++ W E +
Sbjct 1342 INGGE------SAPTTIIQHTAVP--PPTNLRFTN----IGPDNIRVTWSPPTSIELSSY 1389
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
++ Y + + + +T + V + L + V + +
Sbjct 1390 LVRYS-PVKKPDDVTELSLSPSTNMVVLSNLLPFTEYLVSVHSVYEERESSSLNGVAKTH 1448
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
P + N V W PR + Y + + + + ++ + +
Sbjct 1449 LDSPTGIAFSEITPNSFTVHWIAPRGPITGYRIRYQL--ESGAGRPKEERVPPSRNS-IT 1505
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
+L YL+++ + P A + + N + W+
Sbjct 1506 LTHLIPGSEYLVSIIAINGQQESLP---LAGQQATVSDVPTDLEVTSSSPNTLTISWEAP 1562
Query 543 PVDVQNGFIRNYTIFYRTIIGN--ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
V +R Y I Y G+ E V + T+ L Y + + A T G
Sbjct 1563 AVS-----VRYYRITYSQTGGHGPEKEFTVPGTSNTATIRGLNPGVSYTITVYAVTGRGD 1617
Query 601 KDGPEFTFTT 610
T
Sbjct 1618 SPASSKPLTI 1627
Score = 138 bits (346), Expect = 1e-31, Method: Composition-based stats.
Identities = 69/389 (18%), Positives = 129/389 (33%), Gaps = 45/389 (12%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP NL N +++TW+ P+ S+ + Y ++Y + + + +
Sbjct 1360 PPTNLRFTNIG--PDNIRVTWSPPT--SIELSSYLVRYSPVKKPD--DVTELSLSPSTNM 1413
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+ +L PFTEY+ + + E+ + S +G+ S + +I P+
Sbjct 1414 VVLSNLLPFTEYLVSVHSVYEERE------SSSLNGVAKTHLDSPTGIAFSEITPN---- 1463
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY------TVNATKLTVNLTNDRYL 397
+ + W G I Y + + + N+ LT + YL
Sbjct 1464 --SFTVHW-----IAPRGPITGYRIRYQLESGAGRPKEERVPPSRNSITLTHLIPGSEYL 1516
Query 398 ATLTVRNLVGKS-DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
++ N +S A D V N L + W P SV+ Y +
Sbjct 1517 VSIIAINGQQESLPLAGQQATVSDVPTDLEVTS----SSPNTLTISWEAPAVSVRYYRIT 1572
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ P GT + +RG L Y ITV V G S +
Sbjct 1573 YSQTGGHGPEKEF--TVPGTSNTATIRG-LNPGVSYTITVYAVTGRGDSPASSKPLTIIH 1629
Query 517 AP-PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY--RTIIGNETAVNVDSS 573
+ + + + ++W P G + Y + ++ G + +
Sbjct 1630 KTDVDQPIDMAVTDIQDHSIHVKWSPPP-----GPVTGYRVTSVPKSGQGETFSQVISPD 1684
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
TE T+ L Y+V + + + G +
Sbjct 1685 QTEVTIVGLQPAVEYVVSIYSQGENGESE 1713
Score = 135 bits (339), Expect = 8e-31, Method: Composition-based stats.
Identities = 86/550 (16%), Positives = 179/550 (33%), Gaps = 62/550 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
+ P +L + + W+ + T S+ H T + T+
Sbjct 1538 VSDVPTDLEVTSSSPNTLTISWEAPAVSVRYYRIT-YSQTGGHGPEKEFTVPGTSNTATI 1596
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
V+ + V A G + ++K + P +++V + ++ S + + W
Sbjct 1597 RGLNPG-VSYTITVYAVTGRGDSPASSKPLTIIHKTDVDQPIDMAVTDIQDHS--IHVKW 1653
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ P + Y + K + + + ++ T+ L+P EYV I E
Sbjct 1654 SPP---PGPVTGYRVTSVPKSGQG--ETFSQVISPDQTEVTIVGLQPAVEYVVSIYSQGE 1708
Query 305 DGKGYWSDWSEEA--SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
+G+ SE + +T D P G +++L W+ +G+
Sbjct 1709 NGE------SEPLVETAVTNIDNPKGL--------TFTDVGVDSIRLAWEV-----PDGQ 1749
Query 363 ILDYEVTLTRWKSHL------QNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
+ Y VT + + + + +L Y ++ + +S +
Sbjct 1750 VTRYRVTYSSPEDGVKELFPAPEGDDDTAELHGLRPGTEYTVSIVALHDDMESKP----L 1805
Query 417 PACDFQATHPVMDLK-AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
A +L+ + + + W P + Y++ V + T +
Sbjct 1806 IGIQSTAIPAPTNLQFSQVTPSGFSLSWHAPTVHLTGYLV--RVNPKEKTGPTKEVRLSP 1863
Query 476 TVHRTYLRGNLAESKCYLITVTPVY-ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE 534
V T + G L + Y + V + + + + + L P + P R + V +
Sbjct 1864 GVAATTVTG-LMVATKYEVNVYALKDSLTSQPLQGLISTLDNVSPPRRP--RIQDVTETT 1920
Query 535 AVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
L W + I + I N VD+ +T++ L T Y + +
Sbjct 1921 VTLSWR-TKTET----ITGFQIDAIPADGQNPIRRTVDADLRTFTITGLQPGTDYKIYLY 1975
Query 594 AYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLT------TLLGVLFCFNKR-DL 646
D TT + + + + L T + G + + K L
Sbjct 1976 TLNDNARSSPVTVDVTTAVDSPSNLR-FLTTTSNSLLFTWQPPRARITGYIIRYEKAGGL 2034
Query 647 IKKHIWPNVP 656
IK+H+ P +P
Sbjct 2035 IKEHL-PRLP 2043
Score = 124 bits (310), Expect = 3e-27, Method: Composition-based stats.
Identities = 90/603 (15%), Positives = 179/603 (30%), Gaps = 59/603 (10%)
Query 67 WKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPP 126
WK + ++ T + + Q C G+ + +G P
Sbjct 554 WKCDAIDQCQDTETRQFYQIGDSWEKHLQGVQYQCYCYGKGIGEWHCQPLSTS-QAGTGP 612
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ ++ N +W+ + +H++ N+ L+ + +A +
Sbjct 613 VQ-VIITESANFPTSHPIQWNAPQASHIK-NYILRWKPKLKAGPWKQATIPGHLNSYTIS 670
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK-----------PNPP-HNLSVINSE 234
+ E + + G +F + P PP ++S +E
Sbjct 671 GLKPGILYEGQLISILQYGNREVTTFDFTTTTTIHRHSQTESGETTPLPPLVSISESVTE 730
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+S ++W + S + + ++Y + + +T +S + DL P
Sbjct 731 ITASSFLVSWVSASDT---VSGFRVEYELSEDGDEKRYLE--LPNTATSVNIPDLLPGRR 785
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y + + E+G+ T P P + ++ + W
Sbjct 786 YNVNVYQITEEGEKSL------ILSTTQTTAPDAPPEHNVE-----NVDDTSIMIKW--- 831
Query 355 PPFEANGKILDYEVTLTRWKSHLQN-----YTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
+ I Y V + T N+ LT L Y T+ +S
Sbjct 832 --NKPQAPITGYRVVYSPSVEGSSTELNLPSTANSVTLTELLPGIEYNITIYAVEDSLES 889
Query 410 DAAVLTIPACDFQA---THPVMDLKAFPKDNM-LWVEWTTPRESVKKYILEWCVLSDKAP 465
+ DL+ ++ + + WT+P+ V Y + +S P
Sbjct 890 VPVFIQQGTTGTPQTVIVPSPTDLQLVEVTDVKIIIMWTSPQSEVSGYRVVVKPVS---P 946
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
D Q + NL + Y V V P + K P+ +
Sbjct 947 AGRDVQNLPVNRNTFAEVVNLQPGRTYSFEVYAVNRGQESEPLVGEFATKLDAPT---DL 1003
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDSSHTEYTLSSLTS 584
+ V ++ V+ W I Y + +T G + ++ S T + L +L
Sbjct 1004 QFTDVTESTVVIIWIPPQAK-----IGRYLLSVGQTRGGQPSQFPINPSVTNHKLDNLLP 1058
Query 585 DTLYMVRMAAYTDEGGKDGPEFTFTT--PKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFN 642
T Y V + A F+T P + V + T + + F +
Sbjct 1059 GTEYTVSLVALKGNQQSASASGVFSTLEPVGSIPHYNTEVTETTIVVTWTPVPRIGFKLD 1118
Query 643 KRD 645
R
Sbjct 1119 VRP 1121
Score = 122 bits (305), Expect = 1e-26, Method: Composition-based stats.
Identities = 85/584 (15%), Positives = 169/584 (29%), Gaps = 77/584 (13%)
Query 73 TIPKEQYTIINRTASSVTFTDIASLN----IQLTCNILTFGQLEQNVYGITIISGLPPEK 128
+ + N + TF ++ +L + GQ + + G +
Sbjct 943 PVSPAGRDVQNLPVNRNTFAEVVNLQPGRTYSFEVYAVNRGQESEPLVG---EFATKLDA 999
Query 129 PKNLSCIVNEGKKMRCEWDGGRETHLETNFTLK-SEWATHKFADCKAKRDTPTSCTVDYS 187
P +L + W + + L + + + +
Sbjct 1000 PTDLQFTDVTESTVVIIWIPPQAKI--GRYLLSVGQTRGGQPSQFPINPSVTNHKLDNLL 1057
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP 247
V + A + S F + V P +N +E + + +TWT
Sbjct 1058 PG--TEYTVSLVALKGNQQSASASGVFSTLEPVGSIPHYN-----TEVTETTIVVTWTP- 1109
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
V + + + R P + S S + L P EY + I + +
Sbjct 1110 ----VPRIGFKLDVRPSQGGE----APREVISESGSIVISGLTPGVEYTYSISVLTDG-- 1159
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK-TLPPFEANGKILDY 366
E+ IT +P ++ PS T+ + W ++ P I Y
Sbjct 1160 ------VEKDIPITKTVVTPLSPPTNLRLQPSRDSA--TLTVYWDRSISPG-----ITGY 1206
Query 367 EVTLTRW-----KSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
++ T S + + T + ++V K + +
Sbjct 1207 RISTTPTPMQVGNSLEEEVGPSQTYCVFENLSPGVEYNVSVY--AVKEEEESAPLSQMFL 1264
Query 422 QATHPVMDLK-AFPKDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
Q + D+K D + + WT ++ Y + + P +++ G
Sbjct 1265 QEIPQLTDIKYDDVTDTSIDLRWTPLNSSNIIGYRITVVAAGESVPI---YEEFVGPTDG 1321
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
Y L Y I++ + G +P +I + +R +G + + W
Sbjct 1322 YYKVSGLEPGIDYEISLITLINGGESAPTTII---QHTAVPPPTNLRFTNIGPDNIRVTW 1378
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRM----- 592
+ Y + Y + + T +++ S LS+L T Y+V +
Sbjct 1379 SPPTSIELSS----YLVRYSPVKKPDDVTELSLSPSTNMVVLSNLLPFTEYLVSVHSVYE 1434
Query 593 ---------AAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
A T G F+ TP A P+
Sbjct 1435 ERESSSLNGVAKTHLDSPTGIAFSEITPNSFTVHWIAPRGPITG 1478
Score = 119 bits (298), Expect = 6e-26, Method: Composition-based stats.
Identities = 71/476 (15%), Positives = 147/476 (31%), Gaps = 48/476 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEW--DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
+ P ++ W G T + L+S K R++ T +
Sbjct 1450 DSPTGIAFSEITPNSFTVHWIAPRGPITGYRIRYQLESGAGRPKEERVPPSRNSITLTHL 1509
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ Y V + A N G+ S + + P +L V + + L ++W
Sbjct 1510 IPGSEYL----VSIIAIN--GQQESLPLA--GQQATVSDVPTDLEVTS--SSPNTLTISW 1559
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
P+ V + Y I Y T ++ T++ L P Y + +
Sbjct 1560 EAPA---VSVRYYRITY--SQTGGHGPEKEFTVPGTSNTATIRGLNPGVSYTITVYAVT- 1613
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
G+G S+ + I D + + Q ++ + W P G +
Sbjct 1614 -GRGDSPASSKPLTIIHKTDVDQP-----IDMAVTDIQD-HSIHVKWSPPP-----GPVT 1661
Query 365 DYEVT----LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
Y VT + ++ Q + + T++T+ +++ + ++ L A
Sbjct 1662 GYRVTSVPKSGQGETFSQVISPDQTEVTIVGLQPAVEYVVSIYSQGENGESEPLVETAVT 1721
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ D+ + + W P V +Y + + S + + T
Sbjct 1722 NIDNPKGLTFTDVGVDS-IRLAWEVPDGQVTRYRVTY---SSPEDGVKELFPAPEGDDDT 1777
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
L Y +++ ++ D P ++ ++ +V + L W
Sbjct 1778 AELHGLRPGTEYTVSIVALHDDMESKP---LIGIQSTAIPAPTNLQFSQVTPSGFSLSW- 1833
Query 541 QLPVDVQNGFIRNY--TIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
P + Y + + G V + T++ L T Y V + A
Sbjct 1834 HAPTVH----LTGYLVRVNPKEKTGPTKEVRLSPGVAATTVTGLMVATKYEVNVYA 1885
Score = 118 bits (294), Expect = 2e-25, Method: Composition-based stats.
Identities = 71/477 (15%), Positives = 145/477 (30%), Gaps = 51/477 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
++P +++ + + +W T + + D V
Sbjct 1634 DQPIDMAVTDIQDHSIHVKWSPPPGPVTGYRVTSVPKSGQGETFSQVISPDQTEVTIVGL 1693
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ ++ + EN S+ + V + + P L+ + S ++L W
Sbjct 1694 QPAVEYVVSIYSQGENG----ESEPLVETAVTNI--DNPKGLTFTDVGVDS--IRLAWEV 1745
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P + +Y + Y + + P + + L+P TEY I + +D
Sbjct 1746 P---DGQVTRYRVTYSSPEDGVKELFPA--PEGDDDTAELHGLRPGTEYTVSIVALHDDM 1800
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
+ S+ GI P+ + ++ PS L W + Y
Sbjct 1801 E------SKPLIGIQSTAIPAPTNLQFSQVTPSGFS------LSWHAPTVH-----LTGY 1843
Query 367 EVTLTRWKSHLQNY------TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
V + + V AT +T + +Y + S I D
Sbjct 1844 LVRVNPKEKTGPTKEVRLSPGVAATTVTGLMVATKYEVNVYALKDSLTSQPLQGLISTLD 1903
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ ++ + + + W T E++ + ++ + P ++ RT
Sbjct 1904 NVSPPRRPRIQDV-TETTVTLSWRTKTETITGFQIDAIPADGQNP----IRRTVDADLRT 1958
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
+ L Y I + + + SP ++ +R N + W
Sbjct 1959 FTITGLQPGTDYKIYLYTLNDNARSSPVTVDVTT---AVDSPSNLRFLTTTSNSLLFTWQ 2015
Query 541 QLPVDVQNGFIRNYTIFYRTIIG--NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
I Y I Y G E + + TE TL++L T Y++ + A
Sbjct 2016 PPRAR-----ITGYIIRYEKAGGLIKEHLPRLPAGTTESTLTNLEPGTEYIIYIIAV 2067
Score = 90.3 bits (222), Expect = 6e-17, Method: Composition-based stats.
Identities = 70/437 (16%), Positives = 126/437 (29%), Gaps = 49/437 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ PK L+ +R W+ T + + + + +
Sbjct 1724 DNPKGLTFTDVGVDSIRLAWE--VPDGQVTRYRVTYSSPEDGVKELFPAPEGDDDTAELH 1781
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V + A + + S + P P NL S+ S L+W
Sbjct 1782 GLRPGTEYTVSIVALHD--DMESKPL-IGIQSTAIP-APTNLQ--FSQVTPSGFSLSWHA 1835
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P+ V + Y ++ K+ + + + ++ TV L T+Y + +K+
Sbjct 1836 PT---VHLTGYLVRVNPKEKTGPT--KEVRLSPGVAATTVTGLMVATKYEVNVYALKD-- 1888
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
S S+ G+ P D + T TV L W+T I +
Sbjct 1889 ----SLTSQPLQGLISTLDNVSPPRRPRIQDVTET----TVTLSWRTKTET-----ITGF 1935
Query 367 EVTLTRWKSHLQ-----NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
++ + + +T Y L N +S + +
Sbjct 1936 QIDAIPADGQNPIRRTVDADLRTFTITGLQPGTDYKIYLYTLNDNARSSPVTVDVTT--- 1992
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
P N L W PR + YI+ + + GT T
Sbjct 1993 AVDSPSNLRFLTTTSNSLLFTWQPPRARITGYIIRYEKAGGLIKEHLP-RLPAGTTESTL 2051
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP-------PSKGPTV-RTKKVGKN 533
NL Y+I + V + P + + P P +GP + +N
Sbjct 2052 T--NLEPGTEYIIYIIAVRNNMKSEPLVGRKRTDELPRLVTLPHPGQGPEILDVPTDEEN 2109
Query 534 EAVLEWDQLPVDVQNGF 550
+ Q +D NG
Sbjct 2110 TPHIT--QTKLDNGNGI 2124
>sp|P08887|IL6RA_HUMAN Interleukin-6 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL6R PE=1 SV=1
Length=468
Score = 136 bits (343), Expect = 6e-33, Method: Composition-based stats.
Identities = 47/221 (21%), Positives = 90/221 (41%), Gaps = 13/221 (6%)
Query 118 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATH------KFA 170
+ ++ +PPE+P+ LSC + CEW L T L + +
Sbjct 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEP 164
Query 171 DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
++ SC + V + +++G S F ++P+PP N++V
Sbjct 165 CQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITV 224
Query 231 INSEELSSILKLTWTNPSIKSVII--LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
L +TW +P + L++ ++YR + + T++ +D + + D
Sbjct 225 TAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCVIHD 281
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
+V ++R +E G+G WS+WS EA G + + S
Sbjct 282 AWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTESRSPP 322
>sp|Q28377|FINC_HORSE Fibronectin OS=Equus caballus OX=9796 GN=FN1
PE=2 SV=3
Length=2477
Score = 141 bits (356), Expect = 8e-33, Method: Composition-based stats.
Identities = 107/687 (16%), Positives = 195/687 (28%), Gaps = 71/687 (10%)
Query 125 PPEKPKNLSCIVN-EGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSC 182
P P NL N + + W+ + T ++ + +SC
Sbjct 1173 PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTSGQQGYSLEEVVHADQSSC 1232
Query 183 TV-DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
T + S N+ V+ V D + + P P + + S +
Sbjct 1233 TFENLSPGLEYNVSVY--------TVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIG 1284
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
L WT + S I+ Y I I + S+ +TV L+P +Y +
Sbjct 1285 LRWTP--LNSSTIIGYRITVVAAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDYDISVIT 1340
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ G E++ T + + P + G T+++ W P E
Sbjct 1341 LINGG---------ESAPTTLTQQTAVPPPTDLRFT---NVGPDTMRVTWAPPPSIELTN 1388
Query 362 KILDYE-VTLTRWKSHLQNYT-VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
++ Y V + L NA LT L YL +++ V + +
Sbjct 1389 LLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYLVSVS---SVYEQHESTPLRGRQ 1445
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
P + N V W PR ++ Y + D + + +
Sbjct 1446 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHTGGRPRED--RVPPSRNS 1503
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
NL Y++++ + P + + ++ W
Sbjct 1504 -ITLTNLNPGTEYVVSIVALNGREESPP---LVGQQSTVSDVPRDLEVIATTPTSILISW 1559
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
D V +R Y I Y GN V S + T+S L Y + + A T
Sbjct 1560 DAPAVT-----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1614
Query 598 EGGKDGPE--------------FTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNK 643
G I +P + K
Sbjct 1615 RGDSPASSKPISIDYRTEIDKPSQMQVTDVQDNSISVRWLPSSSPVTGYRVTTT----PK 1670
Query 644 RDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKP 703
+ PD ++ I P + +++Q +V I + +
Sbjct 1671 NGPGQSKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNQNGESQPLVQTAVTNI--DRPRG 1728
Query 704 FPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVV 763
+D K + +G S ++ S P + + T + +
Sbjct 1729 LAFTDVDVDSIKIAWESPQGQVS----RYRVTYSSPEDGIHELFPAPDGEEDTAEL-QGL 1783
Query 764 HSGYRHQVPSVQVFSRSESTQPLLDSE 790
G + V V + ES QPL+ ++
Sbjct 1784 RPGSEYTVSVVALHDDMES-QPLIGTQ 1809
Score = 139 bits (350), Expect = 4e-32, Method: Composition-based stats.
Identities = 83/537 (15%), Positives = 157/537 (29%), Gaps = 62/537 (12%)
Query 81 IINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPK--NLSCIVNE 138
+++ SS TF ++ S ++ ++ T +++V I + PE P+ +LS +
Sbjct 1224 VVHADQSSCTFENL-SPGLEYNVSVYTVKDDKESV---PISDTIIPEVPQLTDLSFVDIT 1279
Query 139 GKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
+ W T + T+ + + +I V
Sbjct 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV- 1338
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY 257
+ N S V P P +L N +++TW P S+ +
Sbjct 1339 ITLING---GESAPTTLTQQTAVPP--PTDLRFTNVG--PDTMRVTWAPP--PSIELTNL 1389
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
++Y + + + ++ + +L P TEY+ + + E + S
Sbjct 1390 LVRYSPVKNE--EDVAELSISPSDNAVVLTNLLPGTEYLVSVSSVYEQHE------STPL 1441
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL 377
G ID S + + W I Y + +
Sbjct 1442 RGRQK-----TGLDSPTGIDFSDITAN-SFTVHWIAPRAT-----ITGYRIRHHPEHTGG 1490
Query 378 QNY------TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
+ + N+ LT Y+ ++ N +S V + P
Sbjct 1491 RPREDRVPPSRNSITLTNLNPGTEYVVSIVALNGREESPPLVGQQSTV---SDVPRDLEV 1547
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
+ + W P +V+ Y + + +P + T L
Sbjct 1548 IATTPTSILISWDAPAVTVRYYRITYGETGGNSPVQ---EFTVPGSKSTATISGLKPGVD 1604
Query 492 YLITVTPVYADGPGS----PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
Y ITV V G P SI + PS+ + V N + W
Sbjct 1605 YTITVYAVTGRGDSPASSKPISIDYRTEIDKPSQM---QVTDVQDNSISVRWLPS----- 1656
Query 548 NGFIRNYTIFYRTIIGNETAVNVDSS--HTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ + Y + G + + TE T+ L Y+V + A G
Sbjct 1657 SSPVTGYRVTTTPKNGPGQSKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNQNGESQ 1713
Score = 129 bits (325), Expect = 4e-29, Method: Composition-based stats.
Identities = 71/529 (13%), Positives = 153/529 (29%), Gaps = 55/529 (10%)
Query 80 TIINRTASSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNE 138
+ + +S+T T++ ++ L + + G + P++L I
Sbjct 1495 DRVPPSRNSITLTNLNPGTEYVVSIVALNGREESPPLVG---QQSTVSDVPRDLEVIATT 1551
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
+ WD T T + S V+ + V
Sbjct 1552 PTSILISWDAPAVTVRYYRIT--YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1609
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A G + Y+ + + P + V + ++ S + + W S + Y
Sbjct 1610 YAVTGRGDSPASSKPISIDYRTEIDKPSQMQVTDVQDNS--ISVRWLP---SSSPVTGYR 1664
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA- 317
+ K+ S+ ++ T++ L+P EYV + ++G+ S+
Sbjct 1665 VTTTPKNGPGQSKTKTAG--PDQTEMTIEGLQPTVEYVVSVYAQNQNGE------SQPLV 1716
Query 318 -SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
+ +T DRP +D ++++ W+ G++ Y VT + +
Sbjct 1717 QTAVTNIDRPRGLAFTDVDVD--------SIKIAWE-----SPQGQVSRYRVTYSSPEDG 1763
Query 377 LQNYT------VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
+ + +L Y ++ + +S + A +L
Sbjct 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQP----LIGTQSTAIPAPTEL 1819
Query 431 K-AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
K L +WT P + Y + V + + G L +
Sbjct 1820 KFTQVTPTSLTAQWTAPNVQLTGYRV--RVTPKEKTGPMKEINLAPDSTSVVVSG-LMVA 1876
Query 490 KCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y ++V + P + S R + + W +
Sbjct 1877 TKYEVSVYALKDTLTSRPAQGIVTTLENV-SPPRRARVTDATETTITISWR-TKTET--- 1931
Query 550 FIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
I + + + YT++ L T Y + + D
Sbjct 1932 -ITGFQVDAVPANGQPPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND 1979
Score = 129 bits (323), Expect = 7e-29, Method: Composition-based stats.
Identities = 73/477 (15%), Positives = 146/477 (31%), Gaps = 53/477 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+KP + + + W T + K K P +
Sbjct 1634 DKPSQMQVTDVQDNSISVRWLPSSSPVTGYRVTT---TPKNGPGQSKTKTAGPDQTEMTI 1690
Query 187 S-TVYFVNIEVWVEAENALGKVTS-DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
V V V A+N G+ + + P L+ + + S +K+ W
Sbjct 1691 EGLQPTVEYVVSVYAQNQNGESQPLVQTAVTNIDR-----PRGLAFTDVDVDS--IKIAW 1743
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+P + +Y + Y + + P D +Q L+P +EY + + +
Sbjct 1744 ESPQ---GQVSRYRVTYSSPEDGIHELFPAPDGEEDT--AELQGLRPGSEYTVSVVALHD 1798
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
D + S+ G P+ + ++ P+ ++ W N ++
Sbjct 1799 DME------SQPLIGTQSTAIPAPTELKFTQVTPT------SLTAQW-----TAPNVQLT 1841
Query 365 DYEVTLTRWKSHLQNYTVN----ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
Y V +T + +N +T + V+ ++V L +
Sbjct 1842 GYRVRVTPKEKTGPMKEINLAPDSTSVVVSGLMVATKYEVSVYALKDTLTSRPAQGIVTT 1901
Query 421 FQATHPVMDLKAF-PKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ P + + + + W T E++ + ++ + + P + + R
Sbjct 1902 LENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQPPIQRTIKPD----VR 1957
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
+Y L Y I + + + SP I A PS + N ++ W
Sbjct 1958 SYTITGLQPGTDYKIYLYTLNDNARSSPVIIDASTAIDAPS---NLHFLATTPNSLLISW 2014
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH--TEYTLSSLTSDTLYMVRMAA 594
I Y I Y V TE T++ L T Y +++ A
Sbjct 2015 QPPRAR-----ITGYIIKYEKPGSPPREVVPRPHPGVTEATITGLEPGTEYTIQVIA 2066
Score = 127 bits (319), Expect = 2e-28, Method: Composition-based stats.
Identities = 76/477 (16%), Positives = 150/477 (31%), Gaps = 50/477 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P + W R T E + + + +
Sbjct 1450 DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHTGGRPR--EDRVPPSRNSITLT 1507
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ V + A N G+ S + + P +L VI + + + ++W
Sbjct 1508 NLNPGTEYVVSIVALN--GREESPPLV--GQQSTVSDVPRDLEVIAT--TPTSILISWDA 1561
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P+ V + Y I Y + S + ++S+ T+ LKP +Y + + G
Sbjct 1562 PA---VTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
S T D+PS ++ + Q ++ + W ++ + Y
Sbjct 1617 DSPASSKPISIDYRTEIDKPS-------QMQVTDVQDN-SISVRWLP-----SSSPVTGY 1663
Query 367 EVTLTRWKSHLQNYTVNA----TKLTVNLTND--RYLATLTVRNLVGKSDAAVLT-IPAC 419
VT T Q+ T A T++T+ Y+ ++ +N G+S V T +
Sbjct 1664 RVTTTPKNGPGQSKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNQNGESQPLVQTAVTNI 1723
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
D D+ + + + W +P+ V +Y + + S I +
Sbjct 1724 DRPRGLAFTDVDV----DSIKIAWESPQGQVSRYRVTY---SSPEDGIHELFPAPDGEED 1776
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
T L Y ++V ++ D + ++ +V +W
Sbjct 1777 TAELQGLRPGSEYTVSVVALHDD---MESQPLIGTQSTAIPAPTELKFTQVTPTSLTAQW 1833
Query 540 DQLPVDVQNGFIRNYTIFY--RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
N + Y + + G +N+ T +S L T Y V + A
Sbjct 1834 -----TAPNVQLTGYRVRVTPKEKTGPMKEINLAPDSTSVVVSGLMVATKYEVSVYA 1885
Score = 126 bits (317), Expect = 4e-28, Method: Composition-based stats.
Identities = 73/478 (15%), Positives = 141/478 (29%), Gaps = 52/478 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P NL I + W R T+ T + S
Sbjct 998 DAPTNLRFINETESTVIVTWTPPRARIAGYRLTV---GLTRGGQPKQYNVGPSASQYPLR 1054
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
S V + A + F + PP+N +E + + +TWT
Sbjct 1055 SLQPGSEYTVTLVAVKGNQQSPKATGVFTTLQSPGSIPPYN-----TEVTETTIVITWTP 1109
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ + + R P + S S V L P EYV+ I +++
Sbjct 1110 -----APRIGFKLGVRPSQGGE----APREVTSDSGSIVVSGLTPGVEYVYTISVLRD-- 1158
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
G D +T P+ + + + W+ + I Y
Sbjct 1159 -GQERDAPIVKKVVTPLSPPT-------NLHLEANPDTGVLTVSWERSTTPD----ITGY 1206
Query 367 EVTLTRWKSH-----LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+T T + + + T + ++V + ++ + I
Sbjct 1207 RITTTPTSGQQGYSLEEVVHADQSSCTFENLSPGLEYNVSVYTVKDDKES--VPISDTII 1264
Query 422 QATHPVMDLKAFP-KDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ DL D+ + + WT ++ Y + + P D+
Sbjct 1265 PEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSS---VG 1321
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
Y L Y I+V + G +P ++ +Q +R VG + + W
Sbjct 1322 YYTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAVPPPTDLRFTNVGPDTMRVTW 1378
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNET--AVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
P + N + Y + E +++ S L++L T Y+V +++
Sbjct 1379 APPPSIE----LTNLLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYLVSVSSV 1432
Score = 121 bits (302), Expect = 2e-26, Method: Composition-based stats.
Identities = 84/505 (17%), Positives = 156/505 (31%), Gaps = 52/505 (10%)
Query 138 EGKKMRCEWDGGRET--HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN-I 194
W +T + L E ++ D + + + Y VN
Sbjct 732 TASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
++ E E +L TS P+ P + +V ++ S + + W+ P I
Sbjct 792 QISEEGEQSLILSTSQTT--------APDAPPDPTVDQVDDTS--IVVRWSRPQAP---I 838
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
Y I Y + +++ T +S T+ DL+P +Y I ++E+ +
Sbjct 839 TGYRIVYSPSVEGSSTELT---LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVFIQ 895
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV-----T 369
+E +G+ D+ P ++ + + + ++W + Y V
Sbjct 896 QETTGVPRADK-VPPPRDLQFVEVTDVK----ITIMWTP-----PESAVTGYRVDVLPVN 945
Query 370 LTRWKSHLQNYTVNA-TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
L + N ++T Y + N +S + P
Sbjct 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYHFKIFAVNHGRESKPLTGEQTT---KLDAPTN 1002
Query 429 DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
++ + V WT PR + Y L + P Q G Y +L
Sbjct 1003 LRFINETESTVIVTWTPPRARIAGYRLTVGLTRGGQPK----QYNVGPSASQYPLRSLQP 1058
Query 489 SKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
Y +T+ V + + Q+P S P +V + V+ W P
Sbjct 1059 GSEYTVTLVAVKGNQQSPKATGVFTTLQSPGSIPPYNT--EVTETTIVITWTPAPR---- 1112
Query 549 GFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE-FT 607
+ + R G E V S +S LT Y+ ++ D +D P
Sbjct 1113 ---IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTISVLRDGQERDAPIVKK 1169
Query 608 FTTPKFAQGEIEAIVVPVCLAFLLT 632
TP + P ++
Sbjct 1170 VVTPLSPPTNLHLEANPDTGVLTVS 1194
Score = 118 bits (294), Expect = 2e-25, Method: Composition-based stats.
Identities = 69/478 (14%), Positives = 141/478 (29%), Gaps = 66/478 (14%)
Query 145 EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
W ++T+K + + +
Sbjct 653 RWKEATIPGHLNSYTIKGLRPGV---------------VYEGQLISVQHYGHKEVTRFDF 697
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVIN---SEELSSILKLTWTNPSIKSVIILKYNIQY 261
++ + P + + +E +S ++W + S + + ++Y
Sbjct 698 TTTSTSPAVTSNTVTGETTPFSPVVATSESVTEITASSFVVSWVSASDT---VSGFRVEY 754
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+ Q D ST +S + DL P +Y+ + + E+G E++ ++
Sbjct 755 ELSEEGDEPQY--LDLPSTATSVNIPDLLPGRKYIVNVYQISEEG--------EQSLILS 804
Query 322 Y--EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN 379
P P ++ + W I Y + +
Sbjct 805 TSQTTAPDAPPDPTV-----DQVDDTSIVVRW-----SRPQAPITGYRIVYSPSVEGSST 854
Query 380 Y-----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ---ATHPVMDLK 431
T N+ L+ +Y T+ +S + P DL+
Sbjct 855 ELTLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVFIQQETTGVPRADKVPPPRDLQ 914
Query 432 AFPKDNM-LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
++ + + WT P +V Y ++ VL P Q+ + + L+
Sbjct 915 FVEVTDVKITIMWTPPESAVTGYRVD--VLPVNLPGEHG-QRLPISRNTFAEVTGLSPGV 971
Query 491 CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
Y + V P + + K P+ +R ++ ++ W
Sbjct 972 TYHFKIFAVNHGRESKPLTGEQTTKLDAPT---NLRFINETESTVIVTWTPPRAR----- 1023
Query 551 IRNYTIFYR-TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
I Y + T G NV S ++Y L SL + Y V + A +G + P+ T
Sbjct 1024 IAGYRLTVGLTRGGQPKQYNVGPSASQYPLRSLQPGSEYTVTLVAV--KGNQQSPKAT 1079
Score = 114 bits (284), Expect = 3e-24, Method: Composition-based stats.
Identities = 44/387 (11%), Positives = 117/387 (30%), Gaps = 27/387 (7%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + + + + + W P I KY ++++ K+A + +S+
Sbjct 611 PVQVIITETPSQPNSHPIQWNAPEPSH--ISKYILRWKPKNAPG--RWKEATIPGHLNSY 666
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSD-------WSEEASGITYEDRPSKAPSFWYKID 337
T++ L+P Y ++ ++ G + S + T + +
Sbjct 667 TIKGLRPGVVYEGQLISVQHYGHKEVTRFDFTTTSTSPAVTSNTVTGETTPFSPVVATSE 726
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL 397
+ + W + + G ++YE++ + + AT + +
Sbjct 727 SVTEITASSFVVSWVSASDTVS-GFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
+ V + + + +++ + P D + V W+ P+ + Y + +
Sbjct 786 YIVNVYQISEEGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY 845
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP----ESIKAY 513
+ + + +L Y IT+ V + +P +
Sbjct 846 SPSVEGSSTELT----LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVFIQQETTGV 901
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI--IGNETAVNVD 571
+ ++ +V + + W + Y + + G
Sbjct 902 PRADKVPPPRDLQFVEVTDVKITIMWTPP-----ESAVTGYRVDVLPVNLPGEHGQRLPI 956
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDE 598
S +T ++ L+ Y ++ A
Sbjct 957 SRNTFAEVTGLSPGVTYHFKIFAVNHG 983
Score = 94.9 bits (234), Expect = 2e-18, Method: Composition-based stats.
Identities = 59/397 (15%), Positives = 113/397 (28%), Gaps = 39/397 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
++P+ L+ + ++ W+ + + + + D
Sbjct 1724 DRPRGLAFTDVDVDSIKIAWE--SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ 1781
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V V A + + S + P P + ++ + L WT
Sbjct 1782 GLRPGSEYTVSVVALHD--DMESQPL-IGTQSTAIPAP---TELKFTQVTPTSLTAQWTA 1835
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P +V + Y ++ K+ + + A +S V L T+Y + +K+
Sbjct 1836 P---NVQLTGYRVRVTPKEKTGPM--KEINLAPDSTSVVVSGLMVATKYEVSVYALKDTL 1890
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
S A GI P D + T T+ + W+T I +
Sbjct 1891 T------SRPAQGIVTTLENVSPPRRARVTDATET----TITISWRTKTET-----ITGF 1935
Query 367 EVTLTRWKSHLQNY-----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+V V + +T Y L N +S ++
Sbjct 1936 QVDAVPANGQPPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVIIDASTAI- 1994
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
P N L + W PR + YI+++ +P + V
Sbjct 1995 --DAPSNLHFLATTPNSLLISWQPPRARITGYIIKYE--KPGSPPREVVPRPHPGVTEAT 2050
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ G L Y I V + + P + + P
Sbjct 2051 ITG-LEPGTEYTIQVIAIKNNQKSEPLIGRRKTDELP 2086
Score = 58.7 bits (140), Expect = 3e-07, Method: Composition-based stats.
Identities = 52/334 (16%), Positives = 103/334 (31%), Gaps = 37/334 (11%)
Query 501 ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G + ++ Y P + + N ++W+ I Y + ++
Sbjct 593 GIGEWHCQPLQTYPGTTGPVQVI-ITETPSQPNSHPIQWNAPEPSH----ISKYILRWKP 647
Query 561 --IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ--- 615
G + YT+ L +Y ++ + G K+ F FTT +
Sbjct 648 KNAPGRWKEATIPGHLNSYTIKGLRPGVVYEGQLISVQHYGHKEVTRFDFTTTSTSPAVT 707
Query 616 ---------------------GEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPN 654
EI A V T+ G + + + + +
Sbjct 708 SNTVTGETTPFSPVVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLD 767
Query 655 VPDPSKS-HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPF---PEDLKS 710
+P + S +I P N + S P +D
Sbjct 768 LPSTATSVNIPDLLPGRKYIVNVYQISEEGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
Query 711 LDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQ 770
+ + + + G+ S SS+ ++ + + + + VQY+ +++ +Q
Sbjct 828 VVRWSRPQAPITGYRIVYSPSVEGSSTELTLPETANSVTLSDLQPGVQYNITIYAVEENQ 887
Query 771 VPSVQVFSRSESTQ-PLLDSEERPEDLQLVDHVD 803
+ VF + E+T P D P DLQ V+ D
Sbjct 888 ESTP-VFIQQETTGVPRADKVPPPRDLQFVEVTD 920
>sp|Q15375|EPHA7_HUMAN Ephrin type-A receptor 7 OS=Homo sapiens
OX=9606 GN=EPHA7 PE=1 SV=3
Length=998
Score = 140 bits (353), Expect = 1e-32, Method: Composition-based stats.
Identities = 51/219 (23%), Positives = 81/219 (37%), Gaps = 21/219 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADCKAK---R 176
PP P+NL +N+ + EW GR + W + C +
Sbjct 331 PPSAPQNLIFNINQ-TTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYM 389
Query 177 DTPTSCTVDYSTVY----FVNIEVWVEAENALGKVTSDHINFDPVYKV--KPNPPHNLSV 230
T +Y TV N VEA N + ++ F V + P V
Sbjct 390 PQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGV 449
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ L ++L+W P + +I +Y I+Y KD + + +S ++ +LK
Sbjct 450 MKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKD---QRERTYSTVKTKSTSASINNLK 506
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
P T YVF+IR G G ++S T E+ K
Sbjct 507 PGTVYVFQIRAFTAAGYG---NYSPRLDVATLEEATGKM 542
Score = 108 bits (268), Expect = 1e-22, Method: Composition-based stats.
Identities = 45/213 (21%), Positives = 73/213 (34%), Gaps = 20/213 (9%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTP-----RESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
+L + +EW+ P R V IL ++ C+
Sbjct 331 PPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMP 390
Query 478 HRTYLRGN------LAESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTVR 526
+T L N L Y V V S + QA PS+ V
Sbjct 391 QQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVM 450
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSD 585
++V + L W + + NG I Y I Y E T V + T ++++L
Sbjct 451 KERVLQRSVELSWQE--PEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKPG 508
Query 586 TLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGE 617
T+Y+ ++ A+T G + P T + A G+
Sbjct 509 TVYVFQIRAFTAAGYGNYSPRLDVATLEEATGK 541
Score = 78.4 bits (191), Expect = 2e-13, Method: Composition-based stats.
Identities = 50/297 (17%), Positives = 87/297 (29%), Gaps = 36/297 (12%)
Query 162 SEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV-------WVEAENALGKVTSDHINF 214
+ C R S + D E E+ + SD
Sbjct 269 YQQKGDTCEPCG--RGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYV 326
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII-LKYNIQYRTKDASTWSQIP 273
P+ P NL + + L W+ P+ + Y I + +P
Sbjct 327 ACTR--PPSAPQNLIF---NINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVP 381
Query 274 --------PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW-SEEASGITYED 324
P+ T + TV DL Y F + + S S T +
Sbjct 382 CGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQA 441
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT--- 381
PS+ + R+V+L W+ P NG I +YE+ + Y+
Sbjct 442 APSQVSGVMKERVLQ-----RSVELSWQE--PEHPNGVITEYEIKYYEKDQRERTYSTVK 494
Query 382 VNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
+T ++N Y+ + G + + A +AT + + A +
Sbjct 495 TKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSE 551
>sp|P11722|FINC_CHICK Fibronectin OS=Gallus gallus OX=9031 GN=FN1
PE=2 SV=4
Length=2483
Score = 141 bits (354), Expect = 1e-32, Method: Composition-based stats.
Identities = 82/477 (17%), Positives = 152/477 (32%), Gaps = 50/477 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P L W R T E + + R P+ ++
Sbjct 1454 DSPTGLDFSDITANSFTVHWIAPRATITGYKIRHHPEHGVGRPKE---DRVPPSRNSITL 1510
Query 187 STVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ + V + A N G+ S + + P +L V + + L+++W
Sbjct 1511 TNLLPGTEYVVSIIAVN--GREESVPLV--GQQTTVSDVPRDLEV--NPTSPTSLEISWD 1564
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P+ V + Y I Y S S + T S T+ LKP +Y + +
Sbjct 1565 APA---VTVRYYRITYGETGGS--SPVQEFTVPGTMSRATITGLKPGVDYTITVYAVTGR 1619
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G S + T D PS ++ + Q ++ + W ++ +
Sbjct 1620 GDSPASSKPVTVTYKTEIDTPS-------QMQVTDVQDN-SISIRWLP-----SSSPVTG 1666
Query 366 YEVTLTRWKSHLQ----NYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAAVLTIPAC 419
Y VT K H N + T++T+ Y+ ++ +N G+S V T
Sbjct 1667 YRVTAVPKKGHGPTKTKNVPPDQTQVTIEGLQPTVEYMVSVYAQNQNGESLPLVETAVTN 1726
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ + D+ + + W +P+ V +Y + + S I + G
Sbjct 1727 IDRP--KGLTFTEVDVDS-IKIAWESPQGQVTRYRVTY---SSPEDGIHELLPAPGGEED 1780
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
T L Y I + +Y D P + ++ +V + W
Sbjct 1781 TAELHGLRPGSEYTINIVAIYDDMESLP---LTGTQSTAIPPPTNLKFTQVTPTSLTVNW 1837
Query 540 DQLPVDVQNGFIRNYTIFY--RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
+ N + Y + + G +N+ T +S L T Y V + A
Sbjct 1838 -----NAPNVRLTGYRVRVNPKEKTGPMKEINLSPDSTSAVVSGLMVATKYEVSVYA 1889
Score = 138 bits (347), Expect = 9e-32, Method: Composition-based stats.
Identities = 87/535 (16%), Positives = 168/535 (31%), Gaps = 64/535 (12%)
Query 81 IINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPK--NLSCIVNE 138
++ +S TF ++ ++ ++ +++ I I + E P+ +LS +
Sbjct 1228 VVGADQTSCTFENLN-PGVEYNVSVYAVKDDQES---IPISKTITQEVPQLTDLSFVDIT 1283
Query 139 GKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
+ W T + T+ + + + +I V
Sbjct 1284 DSSIGLRWTPLNASTIIGYRITVVAAGESVPIFEDFVDSSVGYYTVTGLEPGIDYDISV- 1342
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY 257
+ N S V P P +L N +++TWT P+ S+++ +
Sbjct 1343 ITLING---GESAPTTLTQQTAVPP--PTDLRFTNVG--PDTMRVTWTAPT--SIVLSSF 1393
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
++Y + + + + + +L P TEY+ R+ + E + S
Sbjct 1394 LVRYSPVKKE--EDVAELTISPSDNVVVLTNLLPGTEYLVRVYSVAEQHE------SAPL 1445
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL 377
SGI +D S + + W I Y++
Sbjct 1446 SGIQK-----TGLDSPTGLDFSDITAN-SFTVHWIAPRAT-----ITGYKIRHHPEHGVG 1494
Query 378 QNY------TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
+ + N+ LT L Y+ ++ N + + + DL+
Sbjct 1495 RPKEDRVPPSRNSITLTNLLPGTEYVVSIIAVN----GREESVPLVGQQTTVSDVPRDLE 1550
Query 432 AFPKD-NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
P L + W P +V+ Y + + +P GT+ R + G L
Sbjct 1551 VNPTSPTSLEISWDAPAVTVRYYRITYGETGGSSP--VQEFTVPGTMSRATITG-LKPGV 1607
Query 491 CYLITVTPVYADGPGS----PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDV 546
Y ITV V G P ++ + PS+ + V N + W
Sbjct 1608 DYTITVYAVTGRGDSPASSKPVTVTYKTEIDTPSQM---QVTDVQDNSISIRWLPS---- 1660
Query 547 QNGFIRNYTIFYRTIIGN--ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ + Y + G+ NV T+ T+ L YMV + A G
Sbjct 1661 -SSPVTGYRVTAVPKKGHGPTKTKNVPPDQTQVTIEGLQPTVEYMVSVYAQNQNG 1714
Score = 129 bits (324), Expect = 6e-29, Method: Composition-based stats.
Identities = 104/733 (14%), Positives = 207/733 (28%), Gaps = 93/733 (13%)
Query 80 TIINRTASSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNE 138
+ + +S+T T++ ++ + + + G + P++L
Sbjct 1499 DRVPPSRNSITLTNLLPGTEYVVSIIAVNGREESVPLVGQQTTVS---DVPRDLEVNPTS 1555
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
+ WD T T + + + V+ + V
Sbjct 1556 PTSLEISWDAPAVTVRYYRITYGETGGSSPVQEFTVPGTMSRATITGLKPG--VDYTITV 1613
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A G + YK + + P + V + ++ S + + W S + Y
Sbjct 1614 YAVTGRGDSPASSKPVTVTYKTEIDTPSQMQVTDVQDNS--ISIRWLP---SSSPVTGYR 1668
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+ K ++ ++ T++ L+P EY+ + ++G+ +
Sbjct 1669 VTAVPK--KGHGPTKTKNVPPDQTQVTIEGLQPTVEYMVSVYAQNQNGESLP----LVET 1722
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
+T DRP +D ++++ W+ G++ Y VT + + +
Sbjct 1723 AVTNIDRPKGLTFTEVDVD--------SIKIAWE-----SPQGQVTRYRVTYSSPEDGIH 1769
Query 379 NYT------VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK- 431
+ +L Y + D L + A P +LK
Sbjct 1770 ELLPAPGGEEDTAELHGLRPGSEYTINIVAIYD----DMESLPLTGTQSTAIPPPTNLKF 1825
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
L V W P + Y + V + + G L +
Sbjct 1826 TQVTPTSLTVNWNAPNVRLTGYRV--RVNPKEKTGPMKEINLSPDSTSAVVSG-LMVATK 1882
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
Y ++V + P + S R + + W + I
Sbjct 1883 YEVSVYALKDSLTSRPAQGVVTTLENV-SPPRRARVTDATETTITITWR-TKTET----I 1936
Query 552 RNYTI--FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT 609
+ I N + YT++ L Y + + E +
Sbjct 1937 TGFQIDAIPAASGQNPIQRTISPDVRTYTITGLQPGNDYKIYLYTLN--------ENARS 1988
Query 610 TPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIW---PNVP-DPSKSHIAQ 665
+P AI P L FL TT L + K + + P P+K + +
Sbjct 1989 SPVVIDAS-TAIDAPSNLRFLTTT-TNSLLASWQPPRAKITGYIIRYDKPGSPAKELLPR 2046
Query 666 WSPHTPPR------------------HNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPED 707
P T N + + D+ + + +P D
Sbjct 2047 PRPGTTEATITGLEPGTEYTIYIIAVKNNQKSEPLVGRKRTDDLPTLITGPHPNQPDMLD 2106
Query 708 LKSLD-----LFKKEKINTEG-HSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYST 761
+ S+D L N G G G + +E+ + +T +T
Sbjct 2107 VPSVDEGTPYLTNNRYDNGNGIQLPGTSGHPQTIGHQGQQVFFEEHGYRRPVPTT---AT 2163
Query 762 VVHSGYRHQVPSV 774
+ G R Q P+V
Sbjct 2164 PLRPGSRRQPPNV 2176
Score = 128 bits (321), Expect = 1e-28, Method: Composition-based stats.
Identities = 86/579 (15%), Positives = 165/579 (28%), Gaps = 45/579 (8%)
Query 39 QLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLN 98
+ S + E + A I +K + + S +
Sbjct 1091 PVGSVPPFNTEVTETSIVITWTPAPRIGFKLGVRPSQGGEAPREVISDSGSIVISGLTPG 1150
Query 99 IQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVN-EGKKMRCEWDGGRETHLETN 157
++ T ++ ++ I P P NL N + + WD +
Sbjct 1151 VEYTYSLTVLMDGQERETPIIRRVTTPLSPPTNLRLEPNPDTGILIVSWDRSTTPGISGY 1210
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPV 217
+ + + + + + V V V A V D +
Sbjct 1211 RVTTAPTNGQQGSTLEEVVGADQTSCTFENLNPGVEYNVSVYA------VKDDQESIPIS 1264
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
+ P + + S + L WT + + I+ Y I S I +
Sbjct 1265 KTITQEVPQLTDLSFVDITDSSIGLRWTP--LNASTIIGYRITVVAAGESV--PIFEDFV 1320
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
S+ +TV L+P +Y + + G E++ T + + P +
Sbjct 1321 DSSVGYYTVTGLEPGIDYDISVITLINGG---------ESAPTTLTQQTAVPPPTDLRFT 1371
Query 338 PSHTQGYRTVQLVWK-TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT-NDR 395
G T+++ W ++ + V + L + + NL
Sbjct 1372 ---NVGPDTMRVTWTAPTSIVLSSFLVRYSPVKKEEDVAELTISPSDNVVVLTNLLPGTE 1428
Query 396 YLATLTVRNLVGKS-DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI 454
YL + +S + + D D+ A N V W PR ++ Y
Sbjct 1429 YLVRVYSVAEQHESAPLSGIQKTGLDSPTGLDFSDITA----NSFTVHWIAPRATITGYK 1484
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+ + + + + NL Y++++ V G ES+
Sbjct 1485 I--RHHPEHGVGRPKEDRVPPSRNS-ITLTNLLPGTEYVVSIIAVN----GREESVPLVG 1537
Query 515 KQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVD 571
+Q S P + + WD V +R Y I Y G+ V
Sbjct 1538 QQTTVSDVPRDLEVNPTSPTSLEISWDAPAVT-----VRYYRITYGETGGSSPVQEFTVP 1592
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ + T++ L Y + + A T G T
Sbjct 1593 GTMSRATITGLKPGVDYTITVYAVTGRGDSPASSKPVTV 1631
Score = 112 bits (279), Expect = 1e-23, Method: Composition-based stats.
Identities = 94/579 (16%), Positives = 182/579 (31%), Gaps = 75/579 (13%)
Query 84 RTASSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLP-----PEKPKNLSCIVN 137
TA+SVT +D+ + ++ + Q V+ +G+P P PK+L +
Sbjct 864 DTATSVTLSDLMPGVQYNISIYAVEEHQESTPVFIQQETTGVPRTDEVPS-PKDLQFVEV 922
Query 138 EGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF------ 191
K+ W +S+ + ++ R + + F
Sbjct 923 SDVKVTIMWTPP-----------QSQVSGYRVEAIPVNRPGQHGQRLPITRSSFAEVVDL 971
Query 192 ---VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
+ A + G+ + K + P NL IN+ E S + + WT P
Sbjct 972 LPGTTYLFKIFAV-SHGRESKP---LTGEQTTKLDAPTNLRFINTTEHS--VLVLWTRPR 1025
Query 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
II Y + + + + + +++L+P TEY + +KED
Sbjct 1026 A---IISGYRLTAGPTRGGQPRTY---NVGPSATKYLLRNLQPGTEYTVYLVAVKED--- 1076
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
E TY+ S P + ++ + W P + +++
Sbjct 1077 -LQSARETGVFTTYQPVGSVPP-------FNTEVTETSIVITWTPAPR-------IGFKL 1121
Query 369 TLTRWKSHL---QNYTVNATKLTVNLT-NDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
+ + + + + + + LT Y +LTV G+ + +
Sbjct 1122 GVRPSQGGEAPREVISDSGSIVISGLTPGVEYTYSLTVLMD-GQERETPIIRRVTTPLSP 1180
Query 425 HPVMDLKAFPKDNMLWVEWTTPRES-VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
+ L+ P +L V W + Y + + + ++ G +
Sbjct 1181 PTNLRLEPNPDTGILIVSWDRSTTPGISGYRVTTAPTNGQQGSTL--EEVVGADQTSCTF 1238
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLP 543
NL Y ++V V D P S K ++ P + + + + L W L
Sbjct 1239 ENLNPGVEYNVSVYAVKDDQESIPIS-KTITQEVP--QLTDLSFVDITDSSIGLRWTPL- 1294
Query 544 VDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
I Y I + VDSS YT++ L Y + + + G
Sbjct 1295 ---NASTIIGYRITVVAAGESVPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGES 1351
Query 602 DGPEFTFTTPKFAQGEIEAI-VVPVCLAFLLTTLLGVLF 639
T T ++ V P + T ++
Sbjct 1352 APTTLTQQTAVPPPTDLRFTNVGPDTMRVTWTAPTSIVL 1390
Score = 109 bits (272), Expect = 7e-23, Method: Composition-based stats.
Identities = 109/711 (15%), Positives = 200/711 (28%), Gaps = 64/711 (9%)
Query 78 QYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVN 137
QY + TA+SV D+ + + EQN+ ++ P+ P S
Sbjct 768 QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEEGEQNLI-LSTSQTTAPDAPPEHSVESV 826
Query 138 EGKKMRCEWDGG--RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIE 195
+ + W T +T + + + + + + V
Sbjct 827 DDTSIVISWSRPQAPITGYRIVYT-----PSVEGSSTELNLPDTATSVTLSDLMPGVQYN 881
Query 196 VWVEAENALGKVTSDHINFDPVYKVKP---NPPHNLSVINSEELSSILKLTWTNPSIKSV 252
+ + A S + P P + E + + WT P
Sbjct 882 ISIYAVEE--HQESTPVFIQQETTGVPRTDEVPSPKDLQFVEVSDVKVTIMWTPPQ---S 936
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSF-TVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+ Y ++ + + TRSSF V DL P T Y+F+I + G S
Sbjct 937 QVSGYRVEAIPVNRPGQH---GQRLPITRSSFAEVVDLLPGTTYLFKIFAVS---HGRES 990
Query 312 DWSEEASGITYEDRPS-KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
+T E AP+ I+ + +V ++W I Y +T
Sbjct 991 KP------LTGEQTTKLDAPTNLRFINTT----EHSVLVLW-----TRPRAIISGYRLTA 1035
Query 371 TRWKSHLQ---NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
+ N +ATK + T+ + + +A T +Q V
Sbjct 1036 GPTRGGQPRTYNVGPSATKYLLRNLQPGTEYTVYLVAVKEDLQSARETGVFTTYQPVGSV 1095
Query 428 MDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
+ + + WT + L +E + + + L
Sbjct 1096 PPFNTEVTETSIVITWTPAPR--IGFKLGVRPSQGGEAP-----REVISDSGSIVISGLT 1148
Query 488 ESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE--AVLEWDQLPVD 545
Y ++T + I+ P PT + + ++ WD
Sbjct 1149 PGVEYTYSLTVLMDGQERETPIIRRVT---TPLSPPTNLRLEPNPDTGILIVSWD---RS 1202
Query 546 VQNGFIRNYTIFYRT---IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
G I Y + G+ V + T T +L Y V + A D+
Sbjct 1203 TTPG-ISGYRVTTAPTNGQQGSTLEEVVGADQTSCTFENLNPGVEYNVSVYAVKDDQESI 1261
Query 603 GPEFTFT--TPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
T T P+ I + + + P D
Sbjct 1262 PISKTITQEVPQLTDLSFVDITDSSIGLRWTPLNASTIIGYRITVVAAGESVPIFEDFVD 1321
Query 661 SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
S + ++ + + N + + + P P DL+ ++
Sbjct 1322 SSVGYYTVTGLEPGIDYDIS-VITLINGGESAPTTLTQQTAVPPPTDLRFTNVGPDTMRV 1380
Query 721 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQV 771
T + I SS + P D E + + S V T + G + V
Sbjct 1381 TWTAPTSIVLSSFLVRYSPVKKEEDVAELTISPSDNVVVLTNLLPGTEYLV 1431
Score = 103 bits (255), Expect = 8e-21, Method: Composition-based stats.
Identities = 47/387 (12%), Positives = 118/387 (30%), Gaps = 28/387 (7%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + + S + + W P I KY +++R K + +S+
Sbjct 616 PVQVIITESTNQPNSHPIQWNAPKTSH--ISKYILRWRPKISG--RHWKEATIPGHLNSY 671
Query 285 TVQDLKPFTEYVFRIRCMKEDG------KGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
T+ LKP Y ++ +++ G + + + + T + P +
Sbjct 672 TISGLKPGVVYEGQLISVQQHGPKEVTRFDFTTTSTTAVTSNTVSGETTLLPPMVATSES 731
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLA 398
+ + W + + G ++YE++ + + AT + +
Sbjct 732 VTEITASSFVVSWVSASDTVS-GFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 790
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWC 458
+ V + + + ++ + P D + + W+ P+ + Y + +
Sbjct 791 IVNVYQISEEGEQNLILSTSQTTAPDAPPEHSVESVDDTSIVISWSRPQAPITGYRIVY- 849
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ + T L +L Y I++ V +P I+ P
Sbjct 850 --TPSVEGSSTELNLPDTATSVTL-SDLMPGVQYNISIYAVEEHQESTPVFIQQETTGVP 906
Query 519 ----PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI---IGNETAVNVD 571
++ +V + + W + Y + + + + +
Sbjct 907 RTDEVPSPKDLQFVEVSDVKVTIMWTPP-----QSQVSGYRVEAIPVNRPGQHGQRLPIT 961
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDE 598
S + L T Y+ ++ A +
Sbjct 962 RSSFAEVV-DLLPGTTYLFKIFAVSHG 987
Score = 58.7 bits (140), Expect = 3e-07, Method: Composition-based stats.
Identities = 64/381 (17%), Positives = 125/381 (33%), Gaps = 43/381 (11%)
Query 501 ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G + ++AY P + + N ++W+ I Y + +R
Sbjct 598 GIGEWHCQPLQAYAGATGPVQVI-ITESTNQPNSHPIQWNAPKTSH----ISKYILRWRP 652
Query 561 IIG--NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD---------------- 602
I + + YT+S L +Y ++ + G K+
Sbjct 653 KISGRHWKEATIPGHLNSYTISGLKPGVVYEGQLISVQQHGPKEVTRFDFTTTSTTAVTS 712
Query 603 ---GPEFTFTTPKFAQGE-IEAIVVPVCLAFLLT---TLLGVLFCFNKRDLIKKHIWPNV 655
E T P A E + I + ++ T+ G + + + + ++
Sbjct 713 NTVSGETTLLPPMVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 772
Query 656 PDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFK 715
P + S P R + Q+ +G + P ++S+D
Sbjct 773 PSTATS--VNIPDLLPGRKYIVNVYQISEEGEQNLILSTSQTTAPDAPPEHSVESVDDTS 830
Query 716 KEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSST-------VQYSTVVHSGYR 768
+ + G + S SS++ N TS T VQY+ +++
Sbjct 831 IVISWSRPQAPITGYRIVYTPSV-EGSSTELNLPDTATSVTLSDLMPGVQYNISIYAVEE 889
Query 769 HQVPSVQVFSRSESTQ-PLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPD 827
HQ + VF + E+T P D P+DLQ V+ D I+ + + + E+ P
Sbjct 890 HQESTP-VFIQQETTGVPRTDEVPSPKDLQFVEVSDVKVTIMWTPPQSQVSGYRVEAIP- 947
Query 828 ISHFERSKQVSSVNEEDFVRL 848
++ + Q + F +
Sbjct 948 VNRPGQHGQRLPITRSSFAEV 968
>sp|Q95209|SORL_RABIT Sortilin-related receptor OS=Oryctolagus
cuniculus OX=9986 GN=SORL1 PE=1 SV=1
Length=2213
Score = 140 bits (353), Expect = 2e-32, Method: Composition-based stats.
Identities = 92/483 (19%), Positives = 165/483 (34%), Gaps = 49/483 (10%)
Query 128 KPKNLSCIVNEGKKMRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
K +NL + + W + + + T+ +
Sbjct 1556 KVQNLQWTADFSGNVTLTWMRPKKMPSAACVYNVYYRVVGESIWKTLETHSNKTNTVLKV 1615
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDP-VYKVKPNPPHNLSVINSEELSSILKLTWT 245
+V V+ + L KV + + + P+ P NL + E ++ W+
Sbjct 1616 LKP-DTTYQVKVQVQ-CLSKVHNTNDFVTLRTPEGLPDAPQNLQLSLHGEEEGVIVGHWS 1673
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P+ +I +Y ++Y + W+ E AS + +++L T Y R+ +
Sbjct 1674 PPTHTHGLIREYIVEYSRSGSKVWT---SERAASNFTE--IKNLLVNTLYTVRVAAVTSR 1728
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G G WSD S+ + + + P P + + T+ + + N K+
Sbjct 1729 GIGNWSD-SKSITTVKGKAIP---PPNIHIDNYDENSLSFTLTV--------DGNIKVNG 1776
Query 366 YEV-------TLTRWKSHLQNYTVNATKLTVNLT-NDRYLATLTVRNLVGKSDAAVLTIP 417
Y V T + K + + + NLT Y + + +G S + +
Sbjct 1777 YVVNLFWAFDTHKQEKKTMNFQGSSVSHKVGNLTAQTAYEISAWAKTDLGDSPLSFEHVT 1836
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK--YILEWCVLSDKAPCITDWQQEDG 475
+ P + +A + + WT PR V Y + L +T
Sbjct 1837 TRGVRPPAPSLKARAINQ-TAVECTWTGPRNVVYGIFYATSFLDLYRNPSSLT-----TP 1890
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP--TVRTKKVGKN 533
+ T L G + + YL V V P S +K P S+ P + GK
Sbjct 1891 LHNATVLVG---KDEQYLFLVRVV--MPYQGPSSDYVVVKMIPDSRLPPRHLHAVHTGKT 1945
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET---AVNVDSSHTEYTLSSLTSDTLYMV 590
AV++W+ P D + + Y I + +I V +S EYTLS L Y V
Sbjct 1946 SAVIKWES-PYDSPDQDLF-YAIAVKDLIRKTDRSYKVKSRNSTVEYTLSKLEPGGKYHV 2003
Query 591 RMA 593
+
Sbjct 2004 IVQ 2006
Score = 129 bits (324), Expect = 5e-29, Method: Composition-based stats.
Identities = 94/613 (15%), Positives = 180/613 (29%), Gaps = 57/613 (9%)
Query 64 YIVWKTNHFTIPKEQYTIINRTASSV-TFTDIASLNIQLTCNILTFGQLEQNVYGITIIS 122
+ ++ +I K T N+T + + + +++ L+ + +
Sbjct 1588 NVYYRVVGESIWKTLETHSNKTNTVLKVLKPDTTYQVKVQVQCLSKVHNTNDFVTLRTPE 1647
Query 123 GLPPEKPKNLSCIVN--EGKKMRCEWDGGRETH-LETNFTLKSEWATHKFADCKAKRDTP 179
GL P+ P+NL ++ E + W TH L + ++ + K +
Sbjct 1648 GL-PDAPQNLQLSLHGEEEGVIVGHWSPPTHTHGLIREYIVEYSRSGSKVWTSERAASNF 1706
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
T + + V V A + G K K PP N+ + N +E S
Sbjct 1707 TEI---KNLLVNTLYTVRVAAVTSRGIGNWSDSKSITTVKGKAIPPPNIHIDNYDENSLS 1763
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
LT ++ + Y + + + + + S V +L T Y
Sbjct 1764 FTLT----VDGNIKVNGYVVNLFWAFDTHKQEKKTMNFQGSSVSHKVGNLTAQTAYEISA 1819
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
+ G S T RP I+ + V+ W P
Sbjct 1820 WAKTDLGDSPLS----FEHVTTRGVRPPAPSLKARAINQT------AVECTWTG-PRNVV 1868
Query 360 NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
G + Y + + + T TV + D L + + ++ +
Sbjct 1869 YG--IFYATSFLDLYRNPSSLTTPLHNATVLVGKDEQYLFLVRVVMPYQGPSSDYVVVKM 1926
Query 420 DFQATHPVMDLKAFPKD-NMLWVEWTTPRESVKKYILEWCVLSDKAPCITD--WQQEDGT 476
+ P L A ++W +P +S + + + + TD ++ +
Sbjct 1927 IPDSRLPPRHLHAVHTGKTSAVIKWESPYDSPDQDLF-YAIAVKDLIRKTDRSYKVKSRN 1985
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAV 536
Y L Y + V S+K P + +
Sbjct 1986 STVEYTLSKLEPGGKYHVIVQLGNMS---KDASVKITT---VSLSAPDALKIITENDHVL 2039
Query 537 LEWDQLPVDV---QNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
L W L + R Y I N TA +++ + +S+L Y +
Sbjct 2040 LFWKSLALKEKYFNES--RGYEIHMFDSAMNITAYLGNTTDNFFKISNLKMGHNYTFTVQ 2097
Query 594 AYTDEG---------------GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
A G G G ++ A+VVP+ LL+ +G
Sbjct 2098 ARCLLGSQICGEPAVLLYDELGSGGDASAMQA--ARSTDVAAVVVPILFLILLSLGVGFA 2155
Query 639 FCFNKRDLIKKHI 651
+ K ++
Sbjct 2156 ILYTKHRRLQSSF 2168
Score = 98.8 bits (244), Expect = 2e-19, Method: Composition-based stats.
Identities = 109/642 (17%), Positives = 210/642 (33%), Gaps = 102/642 (16%)
Query 323 EDRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTLTR-----WKSH 376
E S + + + T + V L W P + + Y V WK+
Sbjct 1545 EKACSDELTVYKVQNLQWTADFSGNVTLTWM-RPKKMPSAACV-YNVYYRVVGESIWKTL 1602
Query 377 LQNYTVNATKLTVNLTNDRYLATLTVRN-LVGKSDAAVLTIPACDFQATHPVM-DLKAFP 434
+ T L V + Y + V+ + +T+ + P L
Sbjct 1603 ETHSNKTNTVLKVLKPDTTYQVKVQVQCLSKVHNTNDFVTLRTPEGLPDAPQNLQLSLHG 1662
Query 435 KDNMLWV-EWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
++ + V W+ P +++YI+E+ W E + T ++ NL +
Sbjct 1663 EEEGVIVGHWSPPTHTHGLIREYIVEY-----SRSGSKVWTSERAASNFTEIK-NLLVNT 1716
Query 491 CYLITVTPVYADGPGS---PESIKAYLKQAPPSKGPTVRTKKVGKNEA--VLEWDQLPVD 545
Y + V V + G G+ +SI +A P P + +N L D
Sbjct 1717 LYTVRVAAVTSRGIGNWSDSKSITTVKGKAIP--PPNIHIDNYDENSLSFTLTVD----- 1769
Query 546 VQNGFIRNYTIF----YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
N + Y + + T + +N S + + +LT+ T Y + A TD G
Sbjct 1770 -GNIKVNGYVVNLFWAFDTHKQEKKTMNFQGSSVSHKVGNLTAQTAYEISAWAKTDLGDS 1828
Query 602 DGPEFTFTT-------PKFAQGEIEAIVVPVCLAFLLTTLLGVLFC------FNKRDLIK 648
TT P I V + G+ + + +
Sbjct 1829 PLSFEHVTTRGVRPPAPSLKARAINQTAVECTWTGPRNVVYGIFYATSFLDLYRNPSSLT 1888
Query 649 KHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDL 708
+ H A ++ F + M G +D VV++ + + P P L
Sbjct 1889 TPL----------HNATVLVGKDEQYLFLVRVVMPYQGPSSDYVVVKMIPDSRLP-PRHL 1937
Query 709 KSLDLFKKEKINT--EGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQY--STVVH 764
++ K + + S + + I +D + ++ +STV+Y S +
Sbjct 1938 HAVHTGKTSAVIKWESPYDSPDQDLFYAIAVKDLIRKTDRSYKVKSRNSTVEYTLSKLEP 1997
Query 765 SGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDG----GDGILPRQQYFKQNCS 820
G H + + S+ S + S P+ L+++ D + +++YF ++
Sbjct 1998 GGKYHVIVQLGNMSKDASVKITTVSLSAPDALKIITENDHVLLFWKSLALKEKYFNES-- 2055
Query 821 QHESSPDISHFERSKQVSS--VNEED-FVRLKQQISDHI------------SQSCGSGQM 865
+I F+ + +++ N D F ++ H SQ CG +
Sbjct 2056 ---RGYEIHMFDSAMNITAYLGNTTDNFFKISNLKMGHNYTFTVQARCLLGSQICGEPAV 2112
Query 866 KMFQEVSAADAFGPGTEGQVERFETVGMEAATDEGMPKSYLP 907
++ D G G + M+AA + +P
Sbjct 2113 LLY------DELGSGGDAS-------AMQAARSTDVAAVVVP 2141
>sp|P54759|EPHA7_RAT Ephrin type-A receptor 7 OS=Rattus norvegicus
OX=10116 GN=Epha7 PE=1 SV=1
Length=998
Score = 139 bits (351), Expect = 2e-32, Method: Composition-based stats.
Identities = 50/215 (23%), Positives = 80/215 (37%), Gaps = 21/215 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADCKAK---R 176
PP P+NL +N+ + EW GR + W + C +
Sbjct 331 PPSAPQNLIFNINQ-TTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYM 389
Query 177 DTPTSCTVDYSTVY----FVNIEVWVEAENALGKVTSDHINFDPVYKV--KPNPPHNLSV 230
T +Y TV N VEA N + ++ F V + P V
Sbjct 390 PQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGV 449
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ L ++L+W P + +I +Y I+Y KD + + +S ++ +LK
Sbjct 450 MKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKD---QRERTYSTLKTKSTSASINNLK 506
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
P T YVF+IR G G ++S T E+
Sbjct 507 PGTVYVFQIRAFTAAGYG---NYSPRLDVATLEEA 538
Score = 106 bits (265), Expect = 3e-22, Method: Composition-based stats.
Identities = 44/213 (21%), Positives = 73/213 (34%), Gaps = 20/213 (9%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTP-----RESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
+L + +EW+ P R V IL ++ C+
Sbjct 331 PPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMP 390
Query 478 HRTYLRGN------LAESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTVR 526
+T L N L Y V V S + QA PS+ V
Sbjct 391 QQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVM 450
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSD 585
++V + L W + + NG I Y I Y E T + + T ++++L
Sbjct 451 KERVLQRSVELSWQE--PEHPNGVITEYEIKYYEKDQRERTYSTLKTKSTSASINNLKPG 508
Query 586 TLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGE 617
T+Y+ ++ A+T G + P T + A G+
Sbjct 509 TVYVFQIRAFTAAGYGNYSPRLDVATLEEASGK 541
Score = 77.6 bits (189), Expect = 3e-13, Method: Composition-based stats.
Identities = 43/246 (17%), Positives = 78/246 (32%), Gaps = 27/246 (11%)
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII-LKYNIQYRTK 264
+ SD P+ P NL + + L W+ P+ + Y I +
Sbjct 318 RAPSDPPYVACTR--PPSAPQNLIF---NINQTTVSLEWSPPADNGGRNDVTYRILCKRC 372
Query 265 DASTWSQIP--------PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW-SE 315
+P P+ T + TV DL Y F + + S
Sbjct 373 SWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFA 432
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
S T + PS+ + R+V+L W+ P NG I +YE+
Sbjct 433 AVSITTGQAAPSQVSGVMKERVLQ-----RSVELSWQE--PEHPNGVITEYEIKYYEKDQ 485
Query 376 HLQNYT---VNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
+ Y+ +T ++N Y+ + G + + A +A+ + +
Sbjct 486 RERTYSTLKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEASGKMFEA 545
Query 431 KAFPKD 436
A +
Sbjct 546 TAVSSE 551
>sp|P02751|FINC_HUMAN Fibronectin OS=Homo sapiens OX=9606 GN=FN1
PE=1 SV=5
Length=2477
Score = 140 bits (353), Expect = 2e-32, Method: Composition-based stats.
Identities = 90/587 (15%), Positives = 175/587 (30%), Gaps = 62/587 (11%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
+SP + + + T V + + + I + +++ SS T
Sbjct 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPK--NLSCIVNEGKKMRCEWDG 148
F ++ S ++ ++ T +++V I + PE P+ +LS + + W
Sbjct 1234 FDNL-SPGLEYNVSVYTVKDDKESV---PISDTIIPEVPQLTDLSFVDITDSSIGLRWTP 1289
Query 149 -GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV 207
T + T+ + + +I V + N
Sbjct 1290 LNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV-ITLING---G 1345
Query 208 TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS 267
S V P P +L N +++TW P S+ + + ++Y
Sbjct 1346 ESAPTTLTQQTAVPP--PTDLRFTNIG--PDTMRVTWAPP--PSIDLTNFLVRYSPVKNE 1399
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
+ + + ++ + +L P TEYV + + E + S G
Sbjct 1400 --EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE------STPLRGRQK----- 1446
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK------SHLQNYT 381
ID S + + W I Y + ++
Sbjct 1447 TGLDSPTGIDFSDITAN-SFTVHWIAPRAT-----ITGYRIRHHPEHFSGRPREDRVPHS 1500
Query 382 VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
N+ LT Y+ ++ N G+ ++ +L +++ A L +
Sbjct 1501 RNSITLTNLTPGTEYVVSIVALN--GREESPLLIGQQSTVSDVPRDLEVVA-ATPTSLLI 1557
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
W P +V+ Y + + +P + T L Y ITV V
Sbjct 1558 SWDAPAVTVRYYRITYGETGGNSPVQ---EFTVPGSKSTATISGLKPGVDYTITVYAVTG 1614
Query 502 DGPGS----PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
G P SI + PS+ + V N ++W + + Y +
Sbjct 1615 RGDSPASSKPISINYRTEIDKPSQM---QVTDVQDNSISVKWLPS-----SSPVTGYRVT 1666
Query 558 YRTIIGNETAVNVDSS--HTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
G + TE T+ L Y+V + A G
Sbjct 1667 TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1713
Score = 140 bits (353), Expect = 2e-32, Method: Composition-based stats.
Identities = 112/699 (16%), Positives = 200/699 (29%), Gaps = 75/699 (11%)
Query 125 PPEKPKNLSCIVN-EGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSC 182
P P NL N + + W+ + T + + +SC
Sbjct 1173 PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSC 1232
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
T D + +E V S I+ + P P + + S + L
Sbjct 1233 TFDNLS---PGLEYNVSVYTVKDDKESVPIS----DTIIPEVPQLTDLSFVDITDSSIGL 1285
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
WT + S I+ Y I I + S+ +TV L+P +Y + +
Sbjct 1286 RWTP--LNSSTIIGYRITVVAAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDYDISVITL 1341
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
G E++ T + + P + G T+++ W P +
Sbjct 1342 INGG---------ESAPTTLTQQTAVPPPTDLRFT---NIGPDTMRVTWAPPPSIDLTNF 1389
Query 363 ILDYE-VTLTRWKSHLQNYT-VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
++ Y V + L NA LT L Y+ +++ V + +
Sbjct 1390 LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS---SVYEQHESTPLRGRQK 1446
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
P + N V W PR ++ Y + + + +
Sbjct 1447 TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRI---RHHPEHFSGRPREDRVPHSRNS 1503
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEW 539
NL Y++++ + G ES +Q+ S P + ++ W
Sbjct 1504 ITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISW 1559
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
D V +R Y I Y GN V S + T+S L Y + + A T
Sbjct 1560 DAPAVT-----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1614
Query 598 EGGKDGPE--------------FTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNK 643
G I +P + K
Sbjct 1615 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT----PK 1670
Query 644 RDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKP 703
PD ++ I P + +++ +V I + K
Sbjct 1671 NGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNI--DRPKG 1728
Query 704 FPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVV 763
+D K + +G S ++ S P + + T + +
Sbjct 1729 LAFTDVDVDSIKIAWESPQGQVS----RYRVTYSSPEDGIHELFPAPDGEEDTAEL-QGL 1783
Query 764 HSGYRHQVPSVQVFSRSESTQPLLDSEER----PEDLQL 798
G + V V + ES QPL+ ++ P DL+
Sbjct 1784 RPGSEYTVSVVALHDDMES-QPLIGTQSTAIPAPTDLKF 1821
Score = 130 bits (327), Expect = 2e-29, Method: Composition-based stats.
Identities = 71/478 (15%), Positives = 145/478 (30%), Gaps = 52/478 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P NL + + W R T+ T + + S
Sbjct 998 DAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLR 1054
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ V + A + F + PP+N +E + + +TWT
Sbjct 1055 NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-----TEVTETTIVITWTP 1109
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ + + R P + S S V L P EYV+ I+ +++
Sbjct 1110 -----APRIGFKLGVRPSQGGE----APREVTSDSGSIVVSGLTPGVEYVYTIQVLRD-- 1158
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
G D +T P+ + + + W+ + I Y
Sbjct 1159 -GQERDAPIVNKVVTPLSPPT-------NLHLEANPDTGVLTVSWERSTTPD----ITGY 1206
Query 367 EVTLTRWKSHLQNYTV-----NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+T T N + + T + + ++V + ++ + I
Sbjct 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES--VPISDTII 1264
Query 422 QATHPVMDLKAFP-KDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ DL D+ + + WT ++ Y + + P D+
Sbjct 1265 PEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSS---VG 1321
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
Y L Y I+V + G +P ++ +Q +R +G + + W
Sbjct 1322 YYTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAVPPPTDLRFTNIGPDTMRVTW 1378
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNET--AVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
P + N+ + Y + E +++ S L++L T Y+V +++
Sbjct 1379 APPPS----IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
Score = 129 bits (324), Expect = 5e-29, Method: Composition-based stats.
Identities = 70/477 (15%), Positives = 146/477 (31%), Gaps = 53/477 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+KP + + + +W T + K K P +
Sbjct 1634 DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTT---TPKNGPGPTKTKTAGPDQTEMTI 1690
Query 187 S-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
V V V A+N G+ + +P + ++ +K+ W
Sbjct 1691 EGLQPTVEYVVSVYAQNPSGESQ-PLVQTAVTNIDRPK-----GLAFTDVDVDSIKIAWE 1744
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
+P + +Y + Y + + P D +Q L+P +EY + + +D
Sbjct 1745 SPQ---GQVSRYRVTYSSPEDGIHELFPAPDGEEDT--AELQGLRPGSEYTVSVVALHDD 1799
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
+ S+ G P+ + ++ P+ ++ W N ++
Sbjct 1800 ME------SQPLIGTQSTAIPAPTDLKFTQVTPT------SLSAQWTP-----PNVQLTG 1842
Query 366 YEVTLTRWKSHLQNYTVN------ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
Y V +T + +N + ++ + +Y ++ S A +
Sbjct 1843 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1902
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ + + + + + W T E++ + ++ + + P + + R
Sbjct 1903 ENVSPPRRARVTD-ATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD----VR 1957
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
+Y L Y I + + + SP I A PS +R N ++ W
Sbjct 1958 SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSW 2014
Query 540 DQLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
I Y I Y E TE T++ L T Y + + A
Sbjct 2015 QPPRAR-----ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2066
Score = 128 bits (320), Expect = 2e-28, Method: Composition-based stats.
Identities = 73/477 (15%), Positives = 148/477 (31%), Gaps = 50/477 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P + W R T E + + + + +
Sbjct 1450 DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR--EDRVPHSRNSITLT 1507
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ V + A N + V + P +L V+ + + L ++W
Sbjct 1508 NLTPGTEYVVSIVALNG---REESPLLIGQQSTVS-DVPRDLEVVAA--TPTSLLISWDA 1561
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P+ V + Y I Y + S + ++S+ T+ LKP +Y + + G
Sbjct 1562 PA---VTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
S + T D+PS ++ + Q ++ + W ++ + Y
Sbjct 1617 DSPASSKPISINYRTEIDKPS-------QMQVTDVQDN-SISVKWLP-----SSSPVTGY 1663
Query 367 EVTLTRWKSHLQNYTVNA----TKLTVNLTND--RYLATLTVRNLVGKSDAAVLT-IPAC 419
VT T T A T++T+ Y+ ++ +N G+S V T +
Sbjct 1664 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNI 1723
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
D D+ + + + W +P+ V +Y + + S I +
Sbjct 1724 DRPKGLAFTDVDV----DSIKIAWESPQGQVSRYRVTY---SSPEDGIHELFPAPDGEED 1776
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
T L Y ++V ++ D + ++ +V +W
Sbjct 1777 TAELQGLRPGSEYTVSVVALHDD---MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQW 1833
Query 540 DQLPVDVQNGFIRNYTIFY--RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
N + Y + + G +N+ + +S L T Y V + A
Sbjct 1834 TPP-----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA 1885
Score = 127 bits (319), Expect = 2e-28, Method: Composition-based stats.
Identities = 71/529 (13%), Positives = 152/529 (29%), Gaps = 55/529 (10%)
Query 80 TIINRTASSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNE 138
+ + +S+T T++ ++ L + + G + P++L +
Sbjct 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIG---QQSTVSDVPRDLEVVAAT 1551
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
+ WD T T + S V+ + V
Sbjct 1552 PTSLLISWDAPAVTVRYYRIT--YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1609
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A G + Y+ + + P + V + ++ S + + W S + Y
Sbjct 1610 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNS--ISVKWLP---SSSPVTGYR 1664
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA- 317
+ K+ ++ ++ T++ L+P EYV + G+ S+
Sbjct 1665 VTTTPKNGPGPTKTKTAG--PDQTEMTIEGLQPTVEYVVSVYAQNPSGE------SQPLV 1716
Query 318 -SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
+ +T DRP +D ++++ W+ G++ Y VT + +
Sbjct 1717 QTAVTNIDRPKGLAFTDVDVD--------SIKIAWE-----SPQGQVSRYRVTYSSPEDG 1763
Query 377 LQNYT------VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
+ + +L Y ++ + +S + A DL
Sbjct 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQP----LIGTQSTAIPAPTDL 1819
Query 431 K-AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
K L +WT P + Y + V + + G L +
Sbjct 1820 KFTQVTPTSLSAQWTPPNVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSG-LMVA 1876
Query 490 KCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y ++V + P + S R + + W +
Sbjct 1877 TKYEVSVYALKDTLTSRPAQGVVTTLENV-SPPRRARVTDATETTITISWR-TKTET--- 1931
Query 550 FIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
I + + G + YT++ L T Y + + D
Sbjct 1932 -ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND 1979
Score = 116 bits (290), Expect = 5e-25, Method: Composition-based stats.
Identities = 85/505 (17%), Positives = 158/505 (31%), Gaps = 52/505 (10%)
Query 138 EGKKMRCEWDGGRET--HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN-I 194
W +T + L E ++ D + + + Y VN
Sbjct 732 TASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
++ + E +L TS P+ P + +V ++ S + + W+ P I
Sbjct 792 QISEDGEQSLILSTSQTT--------APDAPPDTTVDQVDDTS--IVVRWSRPQAP---I 838
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
Y I Y + +++ + T +S T+ DL+P +Y I ++E+ S
Sbjct 839 TGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNITIYAVEEN---QESTPV 892
Query 315 --EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV---T 369
++ + T +P ++ + + V ++W PP A + Y V
Sbjct 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVK----VTIMW--TPPESA---VTGYRVDVIP 943
Query 370 LTRWKSHLQNYTVN-ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+ H Q ++ T V + V V + + P
Sbjct 944 VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVF-AVSHGRESKPLTAQQTTKLDAPTN 1002
Query 429 DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
D+ + V WT PR + Y L + P +V + LR NL
Sbjct 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY---NVGPSVSKYPLR-NLQP 1058
Query 489 SKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
+ Y +++ + + + Q S P +V + V+ W P
Sbjct 1059 ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT--EVTETTIVITWTPAPR---- 1112
Query 549 GFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT- 607
+ + R G E V S +S LT Y+ + D +D P
Sbjct 1113 ---IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNK 1169
Query 608 FTTPKFAQGEIEAIVVPVCLAFLLT 632
TP + P ++
Sbjct 1170 VVTPLSPPTNLHLEANPDTGVLTVS 1194
Score = 115 bits (288), Expect = 1e-24, Method: Composition-based stats.
Identities = 65/398 (16%), Positives = 129/398 (32%), Gaps = 50/398 (13%)
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
+E +S ++W + S + + ++Y + Q D ST +S + DL P
Sbjct 729 TEITASSFVVSWVSASDT---VSGFRVEYELSEEGDEPQY--LDLPSTATSVNIPDLLPG 783
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITY--EDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
+Y+ + + EDG E++ ++ P P ++ +
Sbjct 784 RKYIVNVYQISEDG--------EQSLILSTSQTTAPDAPPDTTV-----DQVDDTSIVVR 830
Query 351 WKTLPPFEANGKILDYEVTLTRWKSHLQNY-----TVNATKLTVNLTNDRYLATLTVRNL 405
W I Y + + T N+ L+ +Y T+
Sbjct 831 W-----SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE 885
Query 406 VGKSDAAVLTIPACDFQA---THPVMDLKAFPKDNM-LWVEWTTPRESVKKYILEWCVLS 461
+S V+ DL+ ++ + + WT P +V Y ++ ++
Sbjct 886 NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN 945
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
Q+ + + L+ Y V V P + + K P+
Sbjct 946 LPGEHG---QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT- 1001
Query 522 GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR-TIIGNETAVNVDSSHTEYTLS 580
++ + ++ W I Y + T G NV S ++Y L
Sbjct 1002 --NLQFVNETDSTVLVRWTPPRAQ-----ITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR 1054
Query 581 SLTSDTLYMVRMAAYTDEGGKDGPEFT--FTTPKFAQG 616
+L + Y V + A +G ++ P+ T FTT +
Sbjct 1055 NLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGSS 1090
Score = 109 bits (273), Expect = 6e-23, Method: Composition-based stats.
Identities = 51/389 (13%), Positives = 123/389 (32%), Gaps = 31/389 (8%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + + + + + W P I KY +++R K++ + +S+
Sbjct 611 PVEVFITETPSQPNSHPIQWNAPQPSH--ISKYILRWRPKNSVG--RWKEATIPGHLNSY 666
Query 285 TVQDLKPFTEYVFRIRCMKEDGK---------GYWSDWSEEASGITYEDRPSKAPSFWYK 335
T++ LKP Y ++ +++ G + ++ +T E P
Sbjct 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP--LVAT 724
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR 395
+ + + W + + G ++YE++ + + AT + +
Sbjct 725 SESVTEITASSFVVSWVSASDTVS-GFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL 455
+ V + + +++ + P D + V W+ P+ + Y +
Sbjct 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITGYRI 843
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
+ S + T + L +L Y IT+ V + +P I+
Sbjct 844 VY---SPSVEGSSTELNLPETANSVTL-SDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
Query 516 QAP----PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI--IGNETAVN 569
P ++ +V + + W + Y + + G
Sbjct 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP-----ESAVTGYRVDVIPVNLPGEHGQRL 954
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
S +T ++ L+ Y ++ A +
Sbjct 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHG 983
Score = 96.5 bits (238), Expect = 9e-19, Method: Composition-based stats.
Identities = 63/397 (16%), Positives = 112/397 (28%), Gaps = 39/397 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
++PK L+ + ++ W+ + + + + D
Sbjct 1724 DRPKGLAFTDVDVDSIKIAWE--SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ 1781
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V V A + + S + P P +L + L WT
Sbjct 1782 GLRPGSEYTVSVVALHD--DMESQPL-IGTQSTAIP-APTDLKFTQV--TPTSLSAQWTP 1835
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P +V + Y ++ K+ + + A SS V L T+Y + +K+
Sbjct 1836 P---NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1890
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
S A G+ P D + T T+ + W+T I +
Sbjct 1891 T------SRPAQGVVTTLENVSPPRRARVTDATET----TITISWRTKTET-----ITGF 1935
Query 367 EVTLTRWKSHLQNY-----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+V V + +T Y L N +S V+
Sbjct 1936 QVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI- 1994
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
P N L V W PR + YI+++ +P + V
Sbjct 1995 --DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPREVVPRPRPGVTEAT 2050
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ G L Y I V + + P + + P
Sbjct 2051 ITG-LEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 58/339 (17%), Positives = 105/339 (31%), Gaps = 47/339 (14%)
Query 501 ADGPGSPESIKAYLKQAPPSKGPT---VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
G + ++ Y P S GP + N ++W+ I Y +
Sbjct 593 GIGEWHCQPLQTY----PSSSGPVEVFITETPSQPNSHPIQWNAPQPSH----ISKYILR 644
Query 558 YRTI--IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF------- 608
+R +G + YT+ L +Y ++ + G ++ F F
Sbjct 645 WRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTST 704
Query 609 ----------TTP-------KFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHI 651
TTP + EI A V T+ G + + +
Sbjct 705 PVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ 764
Query 652 WPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSL 711
+ ++P + S P R + Q+ DG + + P + +
Sbjct 765 YLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQV 822
Query 712 DLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSST-------VQYSTVVH 764
D + + G S S SS++ N S T VQY+ ++
Sbjct 823 DDTSIVVRWSRPQAPITGYRIVYSPSV-EGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
Query 765 SGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVD 803
+ +Q + V + + P D+ P DLQ V+ D
Sbjct 882 AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTD 920
>sp|Q7TPD3|ROBO2_MOUSE Roundabout homolog 2 OS=Mus musculus OX=10090
GN=Robo2 PE=1 SV=2
Length=1470
Score = 140 bits (352), Expect = 2e-32, Method: Composition-based stats.
Identities = 84/411 (20%), Positives = 136/411 (33%), Gaps = 73/411 (18%)
Query 300 RCMKEDGKGYWS---DWSEEASGIT----YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
G+ WS D +E + I+ D P PS D S +V L W+
Sbjct 493 VATSSSGETSWSAVLDVTESGATISKNYDMNDLP-GPPSKPQVTDVSKN----SVTLSWQ 547
Query 353 T-LPPFEANGK--ILDYEVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVG 407
P I + +++ + N+ V T TV N YL + N G
Sbjct 548 PGTPGVLPASAYIIEAFSQSVSNSWQTVANH-VKTTLYTVRGLRPNTIYLFMVRAINPQG 606
Query 408 KSDAAVLTIPACDFQATHPVMDL------------------KAFPKDNMLWVEWTTPRES 449
SD + ++ P + P + + V WT R+
Sbjct 607 LSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVVVRLHNPVVLTPTTVQVTWTVDRQP 666
Query 450 VKKYILEWCVLSDKAPCI---TDWQQEDGTV--HRTYLRGNLAESKCYLITVTPVYADGP 504
++I + V+ + + T WQ D V R+ + NL + Y I V P + +
Sbjct 667 --QFIQGYRVMYRQTSGLQASTVWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQ 724
Query 505 GS-PESIKAYLKQAPPSKGPT----VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
G ES + PS P + + WD P D QNG I+ Y I+
Sbjct 725 GMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPADHQNGIIQEYKIW-- 782
Query 560 TIIGNETAVN----VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE---------- 605
+GNET + VD++ + L Y V +AA T G E
Sbjct 783 -CLGNETRFHINKTVDAAIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGGRN 841
Query 606 --------FTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIK 648
+ T + A + + A + + ++ + +R K
Sbjct 842 EVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRK 892
Score = 121 bits (302), Expect = 2e-26, Method: Composition-based stats.
Identities = 79/525 (15%), Positives = 154/525 (29%), Gaps = 67/525 (13%)
Query 30 YISPESPVVQLHSNFTAVCVLKEKCMDYFHVNAN--YIVWKTNHFTIPKEQYTIINRTAS 87
+ P +V T C K + N P + ++
Sbjct 321 VVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP--TG 378
Query 88 SVTFTDIASLNIQLT-CNILTFGQL---EQNVYGITIISGLPP----EKPKN-------- 131
+T T+I + C LT + + +++ PP + P N
Sbjct 379 DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGT 438
Query 132 --LSCIVNEGKKMRCEWDGGRETHL--ETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
L C W T L + T++ + T + + + +C S
Sbjct 439 ALLKCKATGEPLPVISWLKEGFTFLGRDPRATIQ-DQGTLQIKNLRISDTGTYTCVATSS 497
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP 247
+ V G S + + + + P PP V + + S + L+W
Sbjct 498 SGETSWSA--VLDVTESGATISKNYDMNDL----PGPPSKPQVTDVSKNS--VTLSWQPG 549
Query 248 SIKSVIILKYNIQ-YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ + Y I+ + +++W + + +TV+ L+P T Y+F +R + G
Sbjct 550 TPGVLPASAYIIEAFSQSVSNSWQTVANH---VKTTLYTVRGLRPNTIYLFMVRAINPQG 606
Query 307 KGYWSDWSEEASGITYEDRPSKAP----------SFWYKIDPSHTQGYRTVQLVWKTLPP 356
S S+ P++ ++ TVQ+ W
Sbjct 607 LSDPSPMSDPVRTQDI-SPPAQGVDHRQVQKELGDVVVRLHNPVVLTPTTVQVTWTVDRQ 665
Query 357 FEANGKILDYEVTLTR---------WKSHLQNYTVNATKLTVNLTND-RYLATLTVR-NL 405
+ I Y V + W++ + + VNL Y + N
Sbjct 666 PQ---FIQGYRVMYRQTSGLQASTVWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNE 722
Query 406 VGKSDAAVLTIPACDFQATHPVMDLK----AFPKDNMLWVEWTTPRESVKKYIL-EWCVL 460
D+ T+ + + P + + V W P + I+ E+ +
Sbjct 723 FQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPADHQNGIIQEYKIW 782
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
+ R+ + G L Y + V + G G
Sbjct 783 CLGNETRFHINKTVDAAIRSVVIGGLFPGIQYRVEVAASTSAGVG 827
Score = 65.3 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 27/184 (15%), Positives = 53/184 (29%), Gaps = 11/184 (6%)
Query 138 EGKKMRCEW----DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN 193
++ W + S + V + V
Sbjct 652 TPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQASTVWQNLDAKVPTERSAVLVNLKKGVT 711
Query 194 IEVWVEA-ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE-LSSILKLTWTNP--SI 249
E+ V N + S+ + PP +++V+ S+ + ++W P
Sbjct 712 YEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPADH 771
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
++ II +Y I T I + + S + L P +Y + G G
Sbjct 772 QNGIIQEYKIWC--LGNETRFHIN-KTVDAAIRSVVIGGLFPGIQYRVEVAASTSAGVGV 828
Query 310 WSDW 313
S+
Sbjct 829 KSEP 832
Score = 59.5 bits (142), Expect = 2e-07, Method: Composition-based stats.
Identities = 95/640 (15%), Positives = 171/640 (27%), Gaps = 107/640 (17%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIP-----KEQYTIINRTAS 87
P +V T C I W + + + ++ + S
Sbjct 37 PSDVIVSKGEPTTLNC-------KAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGS 89
Query 88 SVTFTDIASLNIQ-----LTC---NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEG 139
+ + C N L + ++ + P ++ E
Sbjct 90 LFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEP 149
Query 140 KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
+ C+ R T + K + + + R + + + V
Sbjct 150 AILECQ--PPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCV--- 204
Query 200 AENALGKVTSDHINFDPVYKVK-PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
N +G+ SD + P N V+ E + +
Sbjct 205 GTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVE-----------------FRCQ 247
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI-----------RCMKEDGK 307
+Q + W + +D R + ++D +Y RI C+ E+
Sbjct 248 VQGDPQPTVRWKK---DDADLPRGRYDIKD-----DYTLRIKKAMSTDEGTYVCIAENRV 299
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
G E ++ +T RP P F + RTV P E G
Sbjct 300 GK----VEASATLTVRVRPVAPPQFVVRPRDQIVAQGRTVTF------PCETKGNPQP-A 348
Query 368 VTLTRWKSHLQNYT----VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA 423
V + S + ++ +V+ T D T R+ G LT+
Sbjct 349 VFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDL-TITNIQRSDAGYYICQALTVAGSILAK 407
Query 424 TH-PVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV----- 477
V D+ ++ +V L C + + + W +E T
Sbjct 408 AQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGEPLPVISWLKEGFTFLGRDP 467
Query 478 ------HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP-----------PS 520
T NL S T + G S ++ + P
Sbjct 468 RATIQDQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDMNDLPG 527
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI--FYRTIIGNETAVNVDSSHTEYT 578
+ V KN L W V Y I F +++ + V T YT
Sbjct 528 PPSKPQVTDVSKNSVTLSWQPGTPGVL--PASAYIIEAFSQSVSNSWQTVANHVKTTLYT 585
Query 579 LSSLTSDTLYMVRMAAYTDEG-GKDGP-EFTFTTPKFAQG 616
+ L +T+Y+ + A +G P T +
Sbjct 586 VRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPP 625
>sp|P07589|FINC_BOVIN Fibronectin OS=Bos taurus OX=9913 GN=FN1
PE=1 SV=4
Length=2478
Score = 140 bits (352), Expect = 2e-32, Method: Composition-based stats.
Identities = 90/539 (17%), Positives = 160/539 (30%), Gaps = 66/539 (12%)
Query 81 IINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPK--NLSCIVNE 138
+++ SS TF ++ S ++ ++ T +++V I + PE P+ +LS +
Sbjct 1225 VVHADQSSCTFENL-SPGLEYNVSVYTVKDDKESV---PISDTIIPEVPQLTDLSFVDIT 1280
Query 139 GKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
+ W T + T+ + + +I V
Sbjct 1281 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV- 1339
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY 257
+ N S V P P +L N +++TW PS + L
Sbjct 1340 ITLING---GESAPTTLTQQTAVPP--PTDLRFTNVG--PDTMRVTWAPPSSIELTNLL- 1391
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
++Y + + + ++ + +L P TEY+ + + E + S
Sbjct 1392 -VRYSPVKNE--EDVAELSISPSDNAVVLTNLLPGTEYLVSVSSVYEQHE------SIPL 1442
Query 318 SGI--TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
G T D PS ID S + + W I Y +
Sbjct 1443 RGRQKTALDSPSG-------IDFSDITAN-SFTVHWIAPRAT-----ITGYRIRHHPENM 1489
Query 376 HLQNY------TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMD 429
+ + N+ LT Y+ ++ N +S V + P
Sbjct 1490 GGRPREDRVPPSRNSITLTNLNPGTEYVVSIVALNSKEESLPLVGQQSTV---SDVPRDL 1546
Query 430 LKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
L + W P +V+ Y + + +P + T L
Sbjct 1547 EVIAATPTSLLISWDAPAVTVRYYRITYGETGGSSPVQ---EFTVPGSKSTATISGLKPG 1603
Query 490 KCYLITVTPVYADGPGS----PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
Y ITV V G P SI + PS+ + V N + W
Sbjct 1604 VDYTITVYAVTGRGDSPASSKPVSINYRTEIDKPSQM---QVTDVQDNSISVRWLPS--- 1657
Query 546 VQNGFIRNYTIFY--RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ + Y + + G V TE T+ L Y+V + A G
Sbjct 1658 --SSPVTGYRVTTAPKNGPGPSKTKTVGPDQTEMTIEGLQPTVEYVVSVYAQNQNGESQ 1714
Score = 134 bits (338), Expect = 1e-30, Method: Composition-based stats.
Identities = 89/579 (15%), Positives = 166/579 (29%), Gaps = 45/579 (8%)
Query 39 QLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLN 98
L S + E + A I +K + + S +
Sbjct 1088 PLGSIPHYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSESGSIVVSGLTPG 1147
Query 99 IQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVN-EGKKMRCEWDGGRETHLE-T 156
++ I ++ I P P NL N + + W+ +
Sbjct 1148 VEYVYTISVLRDGQERDAPIVKKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY 1207
Query 157 NFTLKSEWATHKFADCKAKRDTPTSCTV-DYSTVYFVNIEVWVEAENALGKVTSDHINFD 215
T ++ + +SCT + S N+ V+ V D +
Sbjct 1208 RITTTPTNGQQGYSLEEVVHADQSSCTFENLSPGLEYNVSVY--------TVKDDKESVP 1259
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPE 275
+ P P + + S + L WT + S I+ Y I I +
Sbjct 1260 ISDTIIPEVPQLTDLSFVDITDSSIGLRWTP--LNSSTIIGYRITVVAAGEGI--PIFED 1315
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
S+ +TV L+P +Y + + G E++ T + + P +
Sbjct 1316 FVDSSVGYYTVTGLEPGIDYDISVITLINGG---------ESAPTTLTQQTAVPPPTDLR 1366
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYE-VTLTRWKSHLQNYT-VNATKLTVNLTN 393
G T+++ W E ++ Y V + L NA LT L
Sbjct 1367 FT---NVGPDTMRVTWAPPSSIELTNLLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1423
Query 394 DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKY 453
YL +++ V + ++ P + N V W PR ++ Y
Sbjct 1424 TEYLVSVS---SVYEQHESIPLRGRQKTALDSPSGIDFSDITANSFTVHWIAPRATITGY 1480
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
+ + D + + + NL Y++++ + + P
Sbjct 1481 RIRHHPENMGGRPRED--RVPPSRNS-ITLTNLNPGTEYVVSIVALNSKEESLP---LVG 1534
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVD 571
+ + ++ WD V +R Y I Y G+ V
Sbjct 1535 QQSTVSDVPRDLEVIAATPTSLLISWDAPAVT-----VRYYRITYGETGGSSPVQEFTVP 1589
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
S + T+S L Y + + A T G +
Sbjct 1590 GSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPVSI 1628
Score = 125 bits (313), Expect = 1e-27, Method: Composition-based stats.
Identities = 70/477 (15%), Positives = 147/477 (31%), Gaps = 53/477 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+KP + + + W T + K K P +
Sbjct 1635 DKPSQMQVTDVQDNSISVRWLPSSSPVTGYRVTTA---PKNGPGPSKTKTVGPDQTEMTI 1691
Query 187 S-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
V V V A+N G+ + +P + ++ +K+ W
Sbjct 1692 EGLQPTVEYVVSVYAQNQNGESQ-PLVQTAVTNIDRPK-----GLAFTDVDVDSIKIAWE 1745
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
+P + +Y + Y + + P D + +Q L+P +EY + + +D
Sbjct 1746 SPQ---GQVSRYRVTYSSPEDGIHELFPAPD--GEEETAELQGLRPGSEYTVSVVALHDD 1800
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
+ S+ G P+ + ++ P+ ++ W N ++
Sbjct 1801 ME------SQPLIGTQSTTIPAPTNLKFTQVTPT------SLTAQW-----TAPNVQLTG 1843
Query 366 YEVTLTRWKSHLQNYTVN------ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
Y V +T + +N + ++ + +Y ++ S A +
Sbjct 1844 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1903
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ + + + + + W T E++ + ++ + + P + + R
Sbjct 1904 ENVSPPRRARVTD-ATETTITISWRTKTETITGFQVDAIPANGQTPIQRTIRPD----VR 1958
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
+Y L Y I + + + SP I A PS +R N ++ W
Sbjct 1959 SYTITGLQPGTDYKIHLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSW 2015
Query 540 DQLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
I Y I Y E TE T++ L T Y +++ A
Sbjct 2016 QPPRAR-----ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIQVIA 2067
Score = 124 bits (312), Expect = 1e-27, Method: Composition-based stats.
Identities = 70/528 (13%), Positives = 150/528 (28%), Gaps = 53/528 (10%)
Query 80 TIINRTASSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNE 138
+ + +S+T T++ ++ L + + G + P++L I
Sbjct 1496 DRVPPSRNSITLTNLNPGTEYVVSIVALNSKEESLPLVG---QQSTVSDVPRDLEVIAAT 1552
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
+ WD T T + S V+ + V
Sbjct 1553 PTSLLISWDAPAVTVRYYRIT--YGETGGSSPVQEFTVPGSKSTATISGLKPGVDYTITV 1610
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A G + Y+ + + P + V + ++ S + + W S + Y
Sbjct 1611 YAVTGRGDSPASSKPVSINYRTEIDKPSQMQVTDVQDNS--ISVRWLP---SSSPVTGYR 1665
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA- 317
+ K+ S+ ++ T++ L+P EYV + ++G+ S+
Sbjct 1666 VTTAPKNGPGPSKTKT--VGPDQTEMTIEGLQPTVEYVVSVYAQNQNGE------SQPLV 1717
Query 318 -SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
+ +T DRP +D ++++ W+ G++ Y VT + +
Sbjct 1718 QTAVTNIDRPKGLAFTDVDVD--------SIKIAWE-----SPQGQVSRYRVTYSSPEDG 1764
Query 377 LQNYT------VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
+ +L Y ++ + +S + T P
Sbjct 1765 IHELFPAPDGEEETAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTTI---PAPTNLK 1821
Query 431 KAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
L +WT P + Y + V + + G L +
Sbjct 1822 FTQVTPTSLTAQWTAPNVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSG-LMVAT 1878
Query 491 CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
Y ++V + P + S R + + W +
Sbjct 1879 KYEVSVYALKDTLTSRPAQGVVTTLENV-SPPRRARVTDATETTITISWR-TKTET---- 1932
Query 551 IRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
I + + + YT++ L T Y + + D
Sbjct 1933 ITGFQVDAIPANGQTPIQRTIRPDVRSYTITGLQPGTDYKIHLYTLND 1980
Score = 121 bits (302), Expect = 2e-26, Method: Composition-based stats.
Identities = 72/477 (15%), Positives = 150/477 (31%), Gaps = 50/477 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P + W R T T + ++ + + +
Sbjct 1451 DSPSGIDFSDITANSFTVHWIAPRATI--TGYRIRHHPENMGGRPREDRVPPSRNSITLT 1508
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ V + A N+ + + + P +L VI + + L ++W
Sbjct 1509 NLNPGTEYVVSIVALNS----KEESLPLVGQQSTVSDVPRDLEVIAA--TPTSLLISWDA 1562
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P+ V + Y I Y S S + ++S+ T+ LKP +Y + + G
Sbjct 1563 PA---VTVRYYRITYGETGGS--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1617
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
S + T D+PS ++ + Q ++ + W ++ + Y
Sbjct 1618 DSPASSKPVSINYRTEIDKPS-------QMQVTDVQDN-SISVRWLP-----SSSPVTGY 1664
Query 367 EVTL----TRWKSHLQNYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAAVLT-IPAC 419
VT S + + T++T+ Y+ ++ +N G+S V T +
Sbjct 1665 RVTTAPKNGPGPSKTKTVGPDQTEMTIEGLQPTVEYVVSVYAQNQNGESQPLVQTAVTNI 1724
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
D D+ + + + W +P+ V +Y + + S I +
Sbjct 1725 DRPKGLAFTDVDV----DSIKIAWESPQGQVSRYRVTY---SSPEDGIHELFPAPDGEEE 1777
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
T L Y ++V ++ D + ++ +V +W
Sbjct 1778 TAELQGLRPGSEYTVSVVALHDD---MESQPLIGTQSTTIPAPTNLKFTQVTPTSLTAQW 1834
Query 540 DQLPVDVQNGFIRNYTIFY--RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
N + Y + + G +N+ + +S L T Y V + A
Sbjct 1835 -----TAPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA 1886
Score = 119 bits (299), Expect = 5e-26, Method: Composition-based stats.
Identities = 46/388 (12%), Positives = 121/388 (31%), Gaps = 29/388 (7%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + + + + + W+ P I KY ++++ K++ + +S+
Sbjct 612 PVQVIITETPSQPNSHPIQWSAPESSH--ISKYILRWKPKNSPD--RWKEATIPGHLNSY 667
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSD-------WSEEASGITYEDRPSKAPSFWYKID 337
T++ L+P Y ++ ++ G+ + S + T + +
Sbjct 668 TIKGLRPGVVYEGQLISVQHYGQREVTRFDFTTTSTSPAVTSNTVTGETTPLSPVVATSE 727
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL 397
+ + W + + G ++YE++ + + AT + +
Sbjct 728 SVTEITASSFVVSWVSASDTVS-GFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 786
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
T+ V + + + ++ + P D + V W+ PR + Y + +
Sbjct 787 YTVNVYEISEEGEQNLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPRAPITGYRIVY 846
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP----ESIKAY 513
S + T + L +L Y IT+ V + +P +
Sbjct 847 ---SPSVEGSSTELNLPETANSVTL-SDLQPGVQYNITIYAVEENQESTPVFIQQETTGV 902
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI---IGNETAVNV 570
+ ++ +V + + W + Y + + + + V
Sbjct 903 PRSDKVPPPRDLQFVEVTDVKITIMWTPP-----ESPVTGYRVDVIPVNLPGEHGQRLPV 957
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
+ ++ L+ Y ++ A
Sbjct 958 SRNTFAE-VTGLSPGVTYHFKVFAVNQG 984
Score = 118 bits (296), Expect = 1e-25, Method: Composition-based stats.
Identities = 64/474 (14%), Positives = 132/474 (28%), Gaps = 58/474 (12%)
Query 145 EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
W ++T+K + + +
Sbjct 654 RWKEATIPGHLNSYTIKGLRPGV-VYEGQLISVQHYGQREVTRFDFTTT----------- 701
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINS-EELSSILKLTWTNPSIKSVIILKYNIQYRT 263
+ + + P P + + E +S ++W + S + + ++Y
Sbjct 702 -STSPAVTSNTVTGETTPLSPVVATSESVTEITASSFVVSWVSASDT---VSGFRVEYEL 757
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+ Q D ST +S + DL P +Y + + E+G+ +
Sbjct 758 SEEGDEPQY--LDLPSTATSVNIPDLLPGRKYTVNVYEISEEGEQ------NLILSTSQT 809
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY--- 380
P P ++ + W I Y + +
Sbjct 810 TAPDAPPDPTV-----DQVDDTSIVVRW-----SRPRAPITGYRIVYSPSVEGSSTELNL 859
Query 381 --TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ---ATHPVMDLKAFPK 435
T N+ L+ +Y T+ +S + P DL+
Sbjct 860 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVFIQQETTGVPRSDKVPPPRDLQFVEV 919
Query 436 DNM-LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
++ + + WT P V Y ++ ++ Q+ + + L+ Y
Sbjct 920 TDVKITIMWTPPESPVTGYRVDVIPVNLPGEHG---QRLPVSRNTFAEVTGLSPGVTYHF 976
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
V V P + + K P+ ++ ++ W I Y
Sbjct 977 KVFAVNQGRESKPLTAQQATKLDAPT---NLQFINETDTTVIVTWTPPRAR-----IVGY 1028
Query 555 TIFYR-TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
+ T G NV + ++Y L +L + Y V + A +G + P T
Sbjct 1029 RLTVGLTRGGQPKQYNVGPAASQYPLRNLQPGSEYAVSLVAV--KGNQQSPRVT 1080
Score = 118 bits (295), Expect = 1e-25, Method: Composition-based stats.
Identities = 70/479 (15%), Positives = 141/479 (29%), Gaps = 54/479 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P NL I + W R + T+ K P +
Sbjct 999 DAPTNLQFINETDTTVIVTWTPPRARIVGYRLTVGLTRGGQP----KQYNVGPAASQYPL 1054
Query 187 STVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ V + A + F + + P +N +E + + +TWT
Sbjct 1055 RNLQPGSEYAVSLVAVKGNQQSPRVTGVFTTLQPLGSIPHYN-----TEVTETTIVITWT 1109
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
+ + + R P + S S V L P EYV+ I +++
Sbjct 1110 P-----APRIGFKLGVRPSQGGE----APREVTSESGSIVVSGLTPGVEYVYTISVLRD- 1159
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G D +T P+ + + + W+ + I
Sbjct 1160 --GQERDAPIVKKVVTPLSPPT-------NLHLEANPDTGVLTVSWERSTTPD----ITG 1206
Query 366 YEVTLTRWKSH-----LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
Y +T T + + + T + ++V + ++ + I
Sbjct 1207 YRITTTPTNGQQGYSLEEVVHADQSSCTFENLSPGLEYNVSVYTVKDDKES--VPISDTI 1264
Query 421 FQATHPVMDLKAFP-KDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
+ DL D+ + + WT ++ Y + + P D+
Sbjct 1265 IPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSS---V 1321
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
Y L Y I+V + G +P ++ +Q +R VG + +
Sbjct 1322 GYYTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAVPPPTDLRFTNVGPDTMRVT 1378
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNET--AVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
W + N + Y + E +++ S L++L T Y+V +++
Sbjct 1379 WAPPSSIE----LTNLLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYLVSVSSV 1433
Score = 116 bits (291), Expect = 5e-25, Method: Composition-based stats.
Identities = 103/723 (14%), Positives = 211/723 (29%), Gaps = 66/723 (9%)
Query 78 QYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVN 137
QY + TA+SV D+ + T N+ + + ++ P+ P + +
Sbjct 765 QYLDLPSTATSVNIPDLL-PGRKYTVNVYEISEEGEQNLILSTSQTTAPDAPPDPTVDQV 823
Query 138 EGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV-DYSTVYFVNIEV 196
+ + W R T + + + + +T S T+ D NI +
Sbjct 824 DDTSIVVRWSRPRAPI--TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI 881
Query 197 WVEAENALGKVTSDHINFDPVYKVKPN-----PPHNLSVINSEELSSILKLTWTNPSIKS 251
+ EN S + P PP +L E + + WT P
Sbjct 882 YAVEENQ----ESTPVFIQQETTGVPRSDKVPPPRDLQ--FVEVTDVKITIMWTPPE--- 932
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+ Y + + + S + V L P Y F++ + +
Sbjct 933 SPVTGYRVDVIPVNLPG--EHGQRLPVSRNTFAEVTGLSPGVTYHFKVFAVNQ------- 983
Query 312 DWSEEASGITYEDRPS-KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
E+ +T + AP+ I+ + T TV + W +I+ Y +T+
Sbjct 984 --GRESKPLTAQQATKLDAPTNLQFINETDT----TVIVTWTP-----PRARIVGYRLTV 1032
Query 371 ---TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
+ N A++ + +++ + G + +T Q +
Sbjct 1033 GLTRGGQPKQYNVGPAASQYPLRNLQPGSEYAVSLVAVKGNQQSPRVTGVFTTLQPLGSI 1092
Query 428 MDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
+ + + WT + L +E + + + L
Sbjct 1093 PHYNTEVTETTIVITWTPAPR--IGFKLGVRPSQGGEAP-----REVTSESGSIVVSGLT 1145
Query 488 ESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE--AVLEWDQLPVD 545
Y+ T++ + +K + P PT + + + W+
Sbjct 1146 PGVEYVYTISVLRDGQERDAPIVKKVV---TPLSPPTNLHLEANPDTGVLTVSWE----R 1198
Query 546 VQNGFIRNYTIFYRTIIGN---ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
I Y I G V + + T +L+ Y V + D+ +
Sbjct 1199 STTPDITGYRITTTPTNGQQGYSLEEVVHADQSSCTFENLSPGLEYNVSVYTVKDD-KES 1257
Query 603 GPEFTFTTPKFAQGEIEAIVVPVCLAF---LLTTLLGVLFCFNKRDLIKKHIWPNVPDPS 659
P P+ Q + V + + + + P D
Sbjct 1258 VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFV 1317
Query 660 KSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKI 719
S + ++ + + N + + + P P DL+ ++
Sbjct 1318 DSSVGYYTVTGLEPGIDYDIS-VITLINGGESAPTTLTQQTAVPPPTDLRFTNVGPDTMR 1376
Query 720 NTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSR 779
T S I ++ + P + D E S + S T + G + V V+ +
Sbjct 1377 VTWAPPSSIELTNLLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYLVSVSSVYEQ 1436
Query 780 SES 782
ES
Sbjct 1437 HES 1439
Score = 97.2 bits (240), Expect = 4e-19, Method: Composition-based stats.
Identities = 64/397 (16%), Positives = 112/397 (28%), Gaps = 39/397 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
++PK L+ + ++ W+ + + + + D
Sbjct 1725 DRPKGLAFTDVDVDSIKIAWE--SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEETAELQ 1782
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V V A + + S + P P NL + L WT
Sbjct 1783 GLRPGSEYTVSVVALHD--DMESQPL-IGTQSTTIP-APTNLKFTQV--TPTSLTAQWTA 1836
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P +V + Y ++ K+ + + A SS V L T+Y + +K+
Sbjct 1837 P---NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1891
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
S A G+ P D + T T+ + W+T I +
Sbjct 1892 T------SRPAQGVVTTLENVSPPRRARVTDATET----TITISWRTKTET-----ITGF 1936
Query 367 EVTLTRWKSHLQNY-----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+V V + +T Y L N +S V+
Sbjct 1937 QVDAIPANGQTPIQRTIRPDVRSYTITGLQPGTDYKIHLYTLNDNARSSPVVIDASTAI- 1995
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
P N L V W PR + YI+++ +P + V
Sbjct 1996 --DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPREVVPRPRPGVTEAT 2051
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ G L Y I V + + P + + P
Sbjct 2052 ITG-LEPGTEYTIQVIALKNNQKSEPLIGRKKTDELP 2087
Score = 54.5 bits (129), Expect = 6e-06, Method: Composition-based stats.
Identities = 50/334 (15%), Positives = 105/334 (31%), Gaps = 37/334 (11%)
Query 501 ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G + + ++ Y + P + + N ++W ++ I Y + ++
Sbjct 594 GIGEWACQPLQTYPDTSGPVQVI-ITETPSQPNSHPIQWSAP----ESSHISKYILRWKP 648
Query 561 IIG--NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ--- 615
+ YT+ L +Y ++ + G ++ F FTT +
Sbjct 649 KNSPDRWKEATIPGHLNSYTIKGLRPGVVYEGQLISVQHYGQREVTRFDFTTTSTSPAVT 708
Query 616 ---------------------GEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPN 654
EI A V T+ G + + + + +
Sbjct 709 SNTVTGETTPLSPVVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLD 768
Query 655 VPDPSKS-HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPF---PEDLKS 710
+P + S +I P N + S P +D
Sbjct 769 LPSTATSVNIPDLLPGRKYTVNVYEISEEGEQNLILSTSQTTAPDAPPDPTVDQVDDTSI 828
Query 711 LDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQ 770
+ + + + G+ S SS+ ++ + + + + VQY+ +++ +Q
Sbjct 829 VVRWSRPRAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQ 888
Query 771 VPSVQVFSRSESTQ-PLLDSEERPEDLQLVDHVD 803
+ VF + E+T P D P DLQ V+ D
Sbjct 889 ESTP-VFIQQETTGVPRSDKVPPPRDLQFVEVTD 921
>sp|P97685|NFASC_RAT Neurofascin OS=Rattus norvegicus OX=10116
GN=Nfasc PE=1 SV=2
Length=1240
Score = 137 bits (345), Expect = 1e-31, Method: Composition-based stats.
Identities = 61/310 (20%), Positives = 102/310 (33%), Gaps = 30/310 (10%)
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR-------WK 374
P P ++ + R+V+L W +P + N I DY V W
Sbjct 620 LAALPKGRPDRPRDLELTD-LAERSVRLTW--IPGDDNNSPITDYVVQFEEDQFQPGVWH 676
Query 375 SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP--VMDLKA 432
H + + + Y + N VG S ++ + A D+K
Sbjct 677 DHSKFPGSVNSAVLHLSPYVNYQFRVIAVNEVGSSHPSLPSERYRTSGAPPESNPSDVKG 736
Query 433 FPK-DNMLWVEWTTPR-----ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
N + + WT +YI++W + W Y+ G
Sbjct 737 EGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRET----WNNVT-VWGSRYVVGQT 791
Query 487 AESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
Y I V G G PE++ Y + PS R ++ LEWD +
Sbjct 792 PVYVPYEIRVQAENDFGKGPEPETVIGYSGEDLPSAPRRFRVRQPNLETINLEWDH--PE 849
Query 546 VQNGFIRNYTIFY----RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
NG + YT+ Y T +G + N + T++++ + Y ++A T G
Sbjct 850 HPNGILIGYTLRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRFSLSARTQVGSG 909
Query 602 DGPEFTFTTP 611
+ TP
Sbjct 910 EAATEESPTP 919
Score = 133 bits (333), Expect = 3e-30, Method: Composition-based stats.
Identities = 57/330 (17%), Positives = 104/330 (32%), Gaps = 27/330 (8%)
Query 204 LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT 263
L + + K +P+ P +L + + E S ++LTW + I Y +Q+
Sbjct 610 LADQATPTNRLAALPKGRPDRPRDLELTDLAERS--VRLTWIPGDDNNSPITDYVVQFEE 667
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+ +S + L P+ Y FR+ + E G + S SE
Sbjct 668 DQFQPGVWHDHSKFPGSVNSAVLH-LSPYVNYQFRVIAVNEVGSSHPSLPSERYRT---- 722
Query 324 DRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTL--TRWKSHLQNY 380
S AP D + +++ W + A G L Y V + N
Sbjct 723 ---SGAPPESNPSDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRETWNNV 779
Query 381 TVNATKLTVNLT--NDRYLATLTVRNLVGKSDAAVLTI-PACDFQATHPVMDLKAFPKDN 437
TV ++ V T Y + N GK I + + + P P
Sbjct 780 TVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPETVIGYSGEDLPSAPRRFRVRQPNLE 839
Query 438 MLWVEW---TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
+ +EW P + Y L + + + + ++ Y
Sbjct 840 TINLEWDHPEHPNGILIGYTLRYVPFNGTKLGKQMVENFSPNQTKFSVQ-RADPVSRYRF 898
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
+++ G G +A +++P P
Sbjct 899 SLSARTQVGSG-----EAATEESP--TPPN 921
Score = 103 bits (257), Expect = 4e-21, Method: Composition-based stats.
Identities = 85/417 (20%), Positives = 148/417 (35%), Gaps = 43/417 (10%)
Query 30 YISPESPVVQLHSNFTAVC------VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIIN 83
Y PE V + + C LK YI + + +
Sbjct 525 YRMPEDQVAKRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAE 584
Query 84 RTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLP---PEKPKNLSCIVNEGK 140
R S T L+ L LT L ++ LP P++P++L +
Sbjct 585 RDQGSYTCMASTELDQDLAKAYLT--VLADQATPTNRLAALPKGRPDRPRDLELTDLAER 642
Query 141 KMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSC-TVDYSTVYFVNIEVWV 198
+R W G + + T++ ++ E + P S + +VN + V
Sbjct 643 SVRLTWIPGDDNNSPITDYVVQFEEDQFQPGVWHDHSKFPGSVNSAVLHLSPYVNYQFRV 702
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHN--LSVINSEELSSILKLTWTNPSIKS--VII 254
A N +G +S Y+ PP + V + +++TWT + S
Sbjct 703 IAVNEVG--SSHPSLPSERYRTSGAPPESNPSDVKGEGTRKNNMEITWTPMNATSAFGPN 760
Query 255 LKYNIQYRTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
L+Y +++R ++ TW+ + + V + Y R++ + GKG
Sbjct 761 LRYIVKWRRRETRETWNNVTVWGSRYVVGQTPV-----YVPYEIRVQAENDFGKGPEP-- 813
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
E G + ED PS AP + P+ T+ L W P NG ++ Y + +
Sbjct 814 -ETVIGYSGEDLPS-APRRFRVRQPNLE----TINLEWDH--PEHPNGILIGYTLRYVPF 865
Query 374 KSH------LQNYTVNATKLTVNL--TNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
++N++ N TK +V RY +L+ R VG +AA P +
Sbjct 866 NGTKLGKQMVENFSPNQTKFSVQRADPVSRYRFSLSARTQVGSGEAATEESPTPPNE 922
Score = 100 bits (248), Expect = 4e-20, Method: Composition-based stats.
Identities = 57/407 (14%), Positives = 111/407 (27%), Gaps = 42/407 (10%)
Query 122 SGLPPEK-PKNLSCIVNEGKKMRCEWDGGRET---HLETNFTLKSEWATHKFADCKAKRD 177
SG PPE P ++ M W T + +K W + +
Sbjct 723 SGAPPESNPSDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVK--WRRRETRETWNNVT 780
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
S V T +V E+ V+AEN GK + P+ P V
Sbjct 781 VWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPETVIGYSGEDLPSAPRRFRVRQPNLE- 839
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ L W +P + I++ Y ++Y + + + E+ + ++ F+VQ P + Y F
Sbjct 840 -TINLEWDHPEHPNGILIGYTLRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRF 898
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
+ + G G E+ P+ P
Sbjct 899 SLSARTQVGSGE----------AATEESPTPPNEATPTAAPPTLPPTT-----------V 937
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
G + + T S + T + + T T +
Sbjct 938 GTTGLVSSTDATALAATSEATTVPIIPTVVPTTVATTIATTTTTTAAATTTTTTESPPTT 997
Query 418 A------CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
+ ++ P + W +++E+ + +
Sbjct 998 TTGTKIHETAPDEQSIWNVTVLPNSKWANITWKHNFRPGTDFVVEYIDSNHTKKTVPVKA 1057
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
Q +L Y + V +G ++ ++
Sbjct 1058 QAQPIQ-----LTDLFPGMTYTLRVYSRDNEGI--SSTVITFMTSTA 1097
>sp|P20241|NRG_DROME Neuroglian OS=Drosophila melanogaster OX=7227
GN=Nrg PE=1 SV=2
Length=1302
Score = 137 bits (345), Expect = 1e-31, Method: Composition-based stats.
Identities = 103/607 (17%), Positives = 197/607 (32%), Gaps = 76/607 (13%)
Query 32 SPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKE-QYTIINRTASSVT 90
P++ V + T C + I W + +I E Q + +S+T
Sbjct 526 EPQNYEVAAGQSATFRC-----NEAHDDTLEIEIDWWKDGQSIDFEAQPRFVKTNDNSLT 580
Query 91 FTDIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPEKPKN--LSCIVNEGKKMRCEWD 147
L+ + TC T +L++ +I P PK ++C + ++ W+
Sbjct 581 IAKTMELDSGEYTCVART--RLDEATARANLIVQDVPNAPKLTGITCQA-DKAEIH--WE 635
Query 148 G-GRETHLETNFTLKSEWA-THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
G ++T++ + T D ++ T + + N V A N +G
Sbjct 636 QQGDNRSPILHYTIQFNTSFTPASWDAAYEKVPNTDSSFVVQMSPWANYTFRVIAFNKIG 695
Query 206 KVTSDHINFDPVYKVKPNPPH--NLSVINSEELSSILKLTWTN-PSIKSVI--ILKYNIQ 260
+ +P+ P +V+ + L ++WT P I+ Y
Sbjct 696 ASPPSAHS--DSCTTQPDVPFKNPDNVVGQGTEPNNLVISWTPMPEIEHNAPNFHYYVSW 753
Query 261 YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
R A+ W D +++ + D F +Y+ ++ + + G+ +EE G
Sbjct 754 KRDIPAAAWENNNIFDWR--QNNIVIADQPTFVKYLIKVVAINDRGESNV--AAEEVVGY 809
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS----- 375
+ EDRP AP+ + + + + W + G Y++
Sbjct 810 SGEDRPLDAPTNFTMRQITSSTSGY---MAWTPVSEESVRGHFKGYKIQTWTENEGEEGL 866
Query 376 ---HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA 432
H++ T NA + Y A + N + + PV L A
Sbjct 867 REIHVKGDTHNALVTQFKPDSKNY-ARILAYNGRFNGPPSAVIDFDTPEGVPSPVQGLDA 925
Query 433 FP-KDNMLWVEWT---TPRESVKKYILEW---CVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+P + + W P + Y + + D D V R + G
Sbjct 926 YPLGSSAFMLHWKKPLYPNGKLTGYKIYYEEVKESYVGERREYDPHITDPRVTRMKMAG- 984
Query 486 LAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
L + Y I++T G GS I+ + + P W+QLP D
Sbjct 985 LKPNSKYRISITATTKMGEGSEHYIEKTTLKDAVNVAPA---------TPSFSWEQLPSD 1035
Query 546 VQNGFIRNYTIFY-----RTIIGNETAVNVDSSHTEYT------------LSSLTSDTLY 588
NG + + I + + ++ T++ + L +T Y
Sbjct 1036 --NGLAK-FRINWLPSTEGHPGTHFFTMHRIKGETQWIRENEEKNSDYQEVGGLDPETAY 1092
Query 589 MVRMAAY 595
R+ +
Sbjct 1093 EFRVVSV 1099
>sp|Q9UF33|EPHA6_HUMAN Ephrin type-A receptor 6 OS=Homo sapiens
OX=9606 GN=EPHA6 PE=1 SV=3
Length=1036
Score = 136 bits (343), Expect = 2e-31, Method: Composition-based stats.
Identities = 53/239 (22%), Positives = 87/239 (36%), Gaps = 20/239 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH-----LETNFTLKSEWATHKFADCKA----- 174
PP P+N+ +NE + EW +T + K T + DC
Sbjct 331 PPSAPRNVVFNINE-TALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFI 389
Query 175 --KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP-NPPHNLSVI 231
+ + V VN +EA N + +++ F + + P + V+
Sbjct 390 PRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVV 449
Query 232 NSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ S + L+W P+ + IL Y I+Y K+ Q+ T S S + LK
Sbjct 450 RKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHE---QLTYSSTRSKAPSVIITGLK 506
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
P T+YVF IR G +S E +G E A + + G T+ +
Sbjct 507 PATKYVFHIRVRTATGYSGYSQKFEFETG--DETSDMAAEQGQILVIATAAVGGFTLLV 563
Score = 86.8 bits (213), Expect = 5e-16, Method: Composition-based stats.
Identities = 44/247 (18%), Positives = 75/247 (30%), Gaps = 26/247 (11%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL-----------SDKAPCITDWQ 471
++ + L +EW+ P ++ + L + V+ D +
Sbjct 331 PPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIP 390
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTVR 526
+ G ++ + + + Y + + S I Q PS VR
Sbjct 391 RHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVR 450
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
+N L W NG I +Y I +Y T + S ++ L
Sbjct 451 KDWASQNSIALSWQA--PAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPA 508
Query 586 TLYMVRMAAYTDEGGKD-GPEFTFTTPK------FAQGEIEAIVVPVCLAFLLTTLLGVL 638
T Y+ + T G +F F T QG+I I F L +L +
Sbjct 509 TKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLF 568
Query 639 FCFNKRD 645
F R
Sbjct 569 FLITGRC 575
Score = 69.1 bits (167), Expect = 1e-10, Method: Composition-based stats.
Identities = 44/210 (21%), Positives = 69/210 (33%), Gaps = 22/210 (10%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWS--- 270
DP PP + + L L W+ PS L Y++ + T
Sbjct 322 DPPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCED 381
Query 271 -----QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD-WSEEASGITYED 324
+ P T +S V D Y F I M + +S + T +D
Sbjct 382 CGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQD 441
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA 384
PS + ++ L W+ P +NG ILDYE+ + Y+
Sbjct 442 APS-----LIGVVRKDWASQNSIALSWQA--PAFSNGAILDYEIKYYEKEHEQLTYSSTR 494
Query 385 TK-----LTVNLTNDRYLATLTVRNLVGKS 409
+K +T +Y+ + VR G S
Sbjct 495 SKAPSVIITGLKPATKYVFHIRVRTATGYS 524
>sp|P78552|I13R1_HUMAN Interleukin-13 receptor subunit alpha-1
OS=Homo sapiens OX=9606 GN=IL13RA1 PE=1 SV=1
Length=427
Score = 132 bits (331), Expect = 2e-31, Method: Composition-based stats.
Identities = 67/312 (21%), Positives = 106/312 (34%), Gaps = 27/312 (9%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTAS-SV 89
+ PV L + +C + ++N +W +HF +++ S V
Sbjct 29 TETQPPVTNLSVSVENLCTVIWTWNPPEGASSNCSLWYFSHFGDKQDKKIAPETRRSIEV 88
Query 90 TFTDIASLNIQLTC--NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD 147
+ L + C N + I+ G P L CI + M+C W
Sbjct 89 PLNERICLQVGSQCSTNESEKPSILVEKC-ISPPEGDPESAVTELQCIWHNLSYMKCSWL 147
Query 148 GGRETHLETNFTLKSEWAT-HKFADCKA--KRDTPTSCTVDYSTVY---FVNIEVWVEAE 201
GR T +TN+TL + K C+ + C+ D + V F V + +
Sbjct 148 PGRNTSPDTNYTLYYWHRSLEKIHQCENIFREGQYFGCSFDLTKVKDSSFEQHSVQIMVK 207
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
+ GK+ +VKP+PPH + N + L + W NP L Y ++
Sbjct 208 DNAGKIKPSFNIVPLTSRVKPDPPH---IKNLSFHNDDLYVQWENPQNFISRCLFYEVEV 264
Query 262 RTKDASTWSQI----------PPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED----GK 307
T + E S F V + P T RIR
Sbjct 265 NNSQTETHNVFYVQEAKCENPEFERNVENTSCFMVPGVLPDTLNTVRIRVKTNKLCYEDD 324
Query 308 GYWSDWSEEASG 319
WS+WS+E S
Sbjct 325 KLWSNWSQEMSI 336
>sp|Q28275|FINC_CANLF Fibronectin (Fragment) OS=Canis lupus familiaris
OX=9615 GN=FN1 PE=2 SV=3
Length=2208
Score = 137 bits (344), Expect = 2e-31, Method: Composition-based stats.
Identities = 103/685 (15%), Positives = 197/685 (29%), Gaps = 78/685 (11%)
Query 125 PPEKPKNLSCIVN-EGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSC 182
P P NL N + + W+ + T ++ + +SC
Sbjct 1137 PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGYSLEEVVHADQSSC 1196
Query 183 TV-DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
T + S N+ V+ V D + + P P + + S +
Sbjct 1197 TFENLSPGLEYNVSVY--------TVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIG 1248
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
L WT + S I+ Y I I + S+ +TV L+P +Y +
Sbjct 1249 LRWTP--LNSSTIIGYRITVVAAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDYDISVIT 1304
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP-PFEAN 360
+ G E++ T + + P + G T+++ W P N
Sbjct 1305 LINGG---------ESAPTTLTQQTAVPPPTDLRFT---NIGPDTMRVTWAPPPSIELTN 1352
Query 361 GKILDYEVTLTRWKSHLQNYTVNATKLTVNLT-NDRYLATLTVRNLVGKSDAAVLTIPAC 419
+ V + L + + NL YL +++ V + +
Sbjct 1353 FLVRYSPVKNEEDVAELSISPSDNVVVLTNLLPGTEYLVSVS---SVYEQHESTPLRGRQ 1409
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
P + N V W PR ++ Y + + + + +
Sbjct 1410 KTGLDSPSGIDFSDITANSFTVHWIAPRATITGYRI--RHHPEHTSGRPREDRVPPSRNS 1467
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
NL Y++++ + +++PP G + ++ W
Sbjct 1468 -ITLTNLNPGTEYVVSIIALNG------------REESPPLIGQQSSLQ--PPTSLLISW 1512
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
D V +R Y I Y V S + T+S L Y + + A T G
Sbjct 1513 DAPAVT-----VRYYRITYGEN-SPVQEFTVPGSKSTATISGLKPGADYTITVYAVTGRG 1566
Query 600 GKD------------GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLI 647
G + + I +P + K
Sbjct 1567 DSPASSKPVSIDYRTGTDSSMQVTDVQDNSISVRWLPSSSPVTGYRVTTT----PKNGPG 1622
Query 648 KKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPED 707
PD ++ I P + ++++ +V I P P D
Sbjct 1623 PSKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNRNGESQPLVQTAVTTI------PAPAD 1676
Query 708 LKSLDLFKKEKINTEGHSSG-IGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSG 766
LK + + + G + + E + ++SS V +V +
Sbjct 1677 LKFTQVTPTSLTAQWTAPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATK 1736
Query 767 YRHQVPSVQVFSRSESTQPLLDSEE 791
Y V +++ S Q ++ + E
Sbjct 1737 YEVSVYALKDTLTSRPAQGVVTTLE 1761
Score = 124 bits (310), Expect = 2e-27, Method: Composition-based stats.
Identities = 67/478 (14%), Positives = 138/478 (29%), Gaps = 52/478 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P NL + W R T+ H S
Sbjct 962 DAPTNLRFANETDSTVLVIWTPPRARIAGYRLTVGPTRGGHPKQ---YNVGPSASQYPLR 1018
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ V + A + F + + PP+N +E + + +TWT
Sbjct 1019 NLQPATEYTVSLVAVKGNQQSPKATGVFTTLQPLSSIPPYN-----TEVTETTIVITWTP 1073
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ + + R P + S S V L P EYV+ I +++
Sbjct 1074 -----APRIGFKLGVRPSQGGE----APREVTSDSGSIVVSGLTPGVEYVYTISVLRDG- 1123
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
+ + S + + + W+ + I Y
Sbjct 1124 ---------QERDTPIVKKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD----ITGY 1170
Query 367 EVTLTRWKSH-----LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+T T + + + T + ++V + ++ + I
Sbjct 1171 RITTTPTNGQQGYSLEEVVHADQSSCTFENLSPGLEYNVSVYTVKDDKES--VPISDTII 1228
Query 422 QATHPVMDLKAFP-KDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ DL D+ + + WT ++ Y + + P D+
Sbjct 1229 PEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSS---VG 1285
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
Y L Y I+V + G +P ++ +Q +R +G + + W
Sbjct 1286 YYTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAVPPPTDLRFTNIGPDTMRVTW 1342
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNET--AVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
P + N+ + Y + E +++ S L++L T Y+V +++
Sbjct 1343 APPPSIE----LTNFLVRYSPVKNEEDVAELSISPSDNVVVLTNLLPGTEYLVSVSSV 1396
Score = 123 bits (307), Expect = 6e-27, Method: Composition-based stats.
Identities = 85/505 (17%), Positives = 156/505 (31%), Gaps = 52/505 (10%)
Query 138 EGKKMRCEWDGGRET--HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN-I 194
W +T + L E ++ D + + + Y VN
Sbjct 696 TASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 755
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
++ E E +L TS P+ P + +V ++ S + + W+ P I
Sbjct 756 QISEEGEQSLILSTSQ--------TTAPDAPPDPAVDRVDDTS--IVVRWSRPQAP---I 802
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
Y I Y + +++ + T +S T+ DL+P +Y I ++E+ +
Sbjct 803 TGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVFIQ 859
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV---TLT 371
+E +G+ D+ P ++ + + + ++W + Y V +
Sbjct 860 QETTGVPRSDK-VPPPRDLQFVEVTDVK----ITIMWTP-----PESTVTGYRVDVIPVN 909
Query 372 RWKSHLQNYTVNATKL---TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
H Q +N T Y + N + + + P
Sbjct 910 LPGEHGQRLPINRNTFAEVTGLSPGVTYHFKVFAVN---QGRESRPLTAEQTTKLDAPTN 966
Query 429 DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
A D+ + V WT PR + Y L P Q G Y NL
Sbjct 967 LRFANETDSTVLVIWTPPRARIAGYRLTVGPTRGGHPK----QYNVGPSASQYPLRNLQP 1022
Query 489 SKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
+ Y +++ V + + Q S P +V + V+ W P
Sbjct 1023 ATEYTVSLVAVKGNQQSPKATGVFTTLQPLSSIPPYNT--EVTETTIVITWTPAPR---- 1076
Query 549 GFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE-FT 607
+ + R G E V S +S LT Y+ ++ D +D P
Sbjct 1077 ---IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTISVLRDGQERDTPIVKK 1133
Query 608 FTTPKFAQGEIEAIVVPVCLAFLLT 632
TP + P ++
Sbjct 1134 VVTPLSPPTNLHLEANPDTGVLTVS 1158
Score = 120 bits (301), Expect = 2e-26, Method: Composition-based stats.
Identities = 73/488 (15%), Positives = 148/488 (30%), Gaps = 62/488 (13%)
Query 145 EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
+W+ +H+ + L+ + +A + V E + +
Sbjct 593 QWNAPEPSHIS-KYILRWKPKNSPGRWKEATIPGHLNSYTIKGLTPGVVYEGQLISVQHY 651
Query 205 GKVTSDHINF------------DPVYKVKPNPPHNLSVINS-EELSSILKLTWTNPSIKS 251
G +F + P P + + E +S ++W + S
Sbjct 652 GHREVTRFDFTTTSTSPPVTSNTVTGETTPLSPVVATSESVTEITASSFVVSWVSASDT- 710
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+ + ++Y + Q D ST +S + DL P +Y+ + + E+G
Sbjct 711 --VSGFRVEYELSEEGDEPQY--LDLPSTATSVNIPDLLPGRKYIVNVYQISEEG----- 761
Query 312 DWSEEASGITY--EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
E++ ++ P P ++ + W I Y +
Sbjct 762 ---EQSLILSTSQTTAPDAPPDPAVDR-----VDDTSIVVRW-----SRPQAPITGYRIV 808
Query 370 LTRWKSHLQNY-----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ-- 422
+ T N+ L+ +Y T+ +S +
Sbjct 809 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVFIQQETTGVPRS 868
Query 423 -ATHPVMDLKAFPKDNM-LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
P DL+ ++ + + WT P +V Y ++ ++ Q+ +
Sbjct 869 DKVPPPRDLQFVEVTDVKITIMWTPPESTVTGYRVDVIPVNLPGEHG---QRLPINRNTF 925
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
L+ Y V V P + + K P+ +R + ++ W
Sbjct 926 AEVTGLSPGVTYHFKVFAVNQGRESRPLTAEQTTKLDAPT---NLRFANETDSTVLVIWT 982
Query 541 QLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
I Y + T G+ NV S ++Y L +L T Y V + A +G
Sbjct 983 PPRAR-----IAGYRLTVGPTRGGHPKQYNVGPSASQYPLRNLQPATEYTVSLVAV--KG 1035
Query 600 GKDGPEFT 607
+ P+ T
Sbjct 1036 NQQSPKAT 1043
Score = 112 bits (280), Expect = 8e-24, Method: Composition-based stats.
Identities = 44/390 (11%), Positives = 121/390 (31%), Gaps = 33/390 (8%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + + + + + W P I KY ++++ K++ + +S+
Sbjct 575 PVQVIITETPSQPNSHPIQWNAPEPSH--ISKYILRWKPKNSPG--RWKEATIPGHLNSY 630
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSD---------WSEEASGITYEDRPSKAPSFWYK 335
T++ L P Y ++ ++ G + ++ +T E P
Sbjct 631 TIKGLTPGVVYEGQLISVQHYGHREVTRFDFTTTSTSPPVTSNTVTGETTPLSP--VVAT 688
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR 395
+ + + W + + G ++YE++ + + AT + +
Sbjct 689 SESVTEITASSFVVSWVSASDTVS-GFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 747
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL 455
+ V + + + +++ + P D + V W+ P+ + Y +
Sbjct 748 RKYIVNVYQISEEGEQSLILSTSQTTAPDAPPDPAVDRVDDTSIVVRWSRPQAPITGYRI 807
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP----ESIK 511
+ S + T + L +L Y IT+ V + +P +
Sbjct 808 VY---SPSVEGSSTELNLPETANSVTL-SDLQPGVQYNITIYAVEENQESTPVFIQQETT 863
Query 512 AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI---IGNETAV 568
+ ++ +V + + W + Y + + + +
Sbjct 864 GVPRSDKVPPPRDLQFVEVTDVKITIMWTPP-----ESTVTGYRVDVIPVNLPGEHGQRL 918
Query 569 NVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
++ + ++ L+ Y ++ A
Sbjct 919 PINRNTFAE-VTGLSPGVTYHFKVFAVNQG 947
Score = 109 bits (273), Expect = 5e-23, Method: Composition-based stats.
Identities = 92/556 (17%), Positives = 148/556 (27%), Gaps = 75/556 (13%)
Query 61 NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI 120
+ I W T+ Y I S V + T + L G
Sbjct 1506 TSLLISWDAPAVTV--RYYRITYGENSPVQEFTVPGSKSTATISGLKPGADYTITVYAVT 1563
Query 121 ISGLPP--EKPKNLSCIVNEGKKM----------RCEWDGGRETHLETNFTLKSEWATHK 168
G P KP ++ M W T +
Sbjct 1564 GRGDSPASSKPVSIDYRTGTDSSMQVTDVQDNSISVRWLPSSSPVTGYRVTT---TPKNG 1620
Query 169 FADCKAKRDTPTSCTVDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHN 227
K K P + V V V A+N G S + V + P +
Sbjct 1621 PGPSKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNRNG--ESQPLVQTAVTTIP--APAD 1676
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
L + L WT P +V + Y ++ K+ + + A SS V
Sbjct 1677 LKFTQV--TPTSLTAQWTAP---NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVS 1729
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV 347
L T+Y + +K+ S A G+ P D + T T+
Sbjct 1730 GLMVATKYEVSVYALKDTLT------SRPAQGVVTTLENVSPPRRARVTDATET----TI 1779
Query 348 QLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY-----TVNATKLTVNLTNDRYLATLTV 402
+ W+T I ++V V + +T Y L
Sbjct 1780 TISWRTKTET-----ITGFQVDAIPANGQNPIQRTIRPDVRSYTITGLQPGTDYKIYLYT 1834
Query 403 RNLVGKSDAAVL--TIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
N +S V+ H + N L V W PR + YI+++
Sbjct 1835 LNDNARSSPVVIDRLTFVFFQPLMHHPTCVFLATTPNSLLVSWQPPRARITGYIIKYE-- 1892
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS 520
+P + V + G L Y I V + + P + Q
Sbjct 1893 KPGSPPREVVPRPRPGVTEATITG-LEPGTEYTIQVIALKNNQKSEPLIGRKKTGQEA-- 1949
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN--VDSSHTEYT 578
++ + W Y I + +E + V + T
Sbjct 1950 -----------LSQTTISWTPFQESS------EYIISCHPVGIDEEPLQFRVPGTSASAT 1992
Query 579 LSSLTSDTLYMVRMAA 594
L+ LT Y + + A
Sbjct 1993 LTGLTRGATYNIIVEA 2008
Score = 105 bits (261), Expect = 1e-21, Method: Composition-based stats.
Identities = 67/478 (14%), Positives = 137/478 (29%), Gaps = 61/478 (13%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P + W R T E + + + + +
Sbjct 1414 DSPSGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHTSGRPR--EDRVPPSRNSITLT 1471
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ V + A N G+ S + + +S + + L ++W
Sbjct 1472 NLNPGTEYVVSIIALN--GREESPPL---------------IGQQSSLQPPTSLLISWDA 1514
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P+ V + Y I Y S + ++S+ T+ LKP +Y + + G
Sbjct 1515 PA---VTVRYYRITY-----GENSPVQEFTVPGSKSTATISGLKPGADYTITVYAVT--G 1564
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
+G S+ S + + Q ++ + W ++ + Y
Sbjct 1565 RGDSPASSKPVSI-------DYRTGTDSSMQVTDVQDN-SISVRWLP-----SSSPVTGY 1611
Query 367 EVTLTRWKSHLQNYTVNA----TKLTVNLTND--RYLATLTVRNLVGKSDAAVLTIPACD 420
VT T + T A T++T+ Y+ ++ +N G+S ++
Sbjct 1612 RVTTTPKNGPGPSKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNRNGESQP-LVQTAVTT 1670
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
A + + P L +WT P + Y + V +
Sbjct 1671 IPAPADLKFTQVTP--TSLTAQWTAPNVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSV 1726
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
+ G L + Y ++V + P + S R + + W
Sbjct 1727 VVSG-LMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-SPPRRARVTDATETTITISWR 1784
Query 541 QLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
+ I + + N + YT++ L T Y + + D
Sbjct 1785 -TKTET----ITGFQVDAIPANGQNPIQRTIRPDVRSYTITGLQPGTDYKIYLYTLND 1837
Score = 55.2 bits (131), Expect = 3e-06, Method: Composition-based stats.
Identities = 53/334 (16%), Positives = 105/334 (31%), Gaps = 37/334 (11%)
Query 501 ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G + ++ Y P + + N ++W+ I Y + ++
Sbjct 557 GIGEWHCQPLQTYPGTTGPVQVI-ITETPSQPNSHPIQWNAPEPSH----ISKYILRWKP 611
Query 561 I--IGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF---------- 608
G + YT+ LT +Y ++ + G ++ F F
Sbjct 612 KNSPGRWKEATIPGHLNSYTIKGLTPGVVYEGQLISVQHYGHREVTRFDFTTTSTSPPVT 671
Query 609 -------TTP-------KFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPN 654
TTP + EI A V T+ G + + + + +
Sbjct 672 SNTVTGETTPLSPVVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLD 731
Query 655 VPDPSKS-HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPF---PEDLKS 710
+P + S +I P N + S P +D
Sbjct 732 LPSTATSVNIPDLLPGRKYIVNVYQISEEGEQSLILSTSQTTAPDAPPDPAVDRVDDTSI 791
Query 711 LDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQ 770
+ + + + G+ S SS+ ++ + + + + VQY+ +++ +Q
Sbjct 792 VVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQ 851
Query 771 VPSVQVFSRSESTQ-PLLDSEERPEDLQLVDHVD 803
+ VF + E+T P D P DLQ V+ D
Sbjct 852 ESTP-VFIQQETTGVPRSDKVPPPRDLQFVEVTD 884
>sp|Q810U3|NFASC_MOUSE Neurofascin OS=Mus musculus OX=10090 GN=Nfasc
PE=1 SV=1
Length=1240
Score = 136 bits (342), Expect = 3e-31, Method: Composition-based stats.
Identities = 58/330 (18%), Positives = 105/330 (32%), Gaps = 27/330 (8%)
Query 204 LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT 263
L + + K +P+ P +L + + E S ++LTW + I Y +Q+
Sbjct 610 LADQATPTNRLAALPKGRPDRPRDLELTDLAERS--VRLTWIPGDDNNSPITDYVVQFEE 667
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+ +S + L P+ Y FR+ + E G + S SE
Sbjct 668 DQFQPGVWHDHSRFPGSVNSAVLH-LSPYVNYQFRVIAVNEVGSSHPSLPSERYRT---- 722
Query 324 DRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTL--TRWKSHLQNY 380
S AP D + +++ W + A G L Y V + N
Sbjct 723 ---SGAPPESNPSDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRETWNNV 779
Query 381 TVNATKLTVNLT--NDRYLATLTVRNLVGKSDAAVLTI-PACDFQATHPVMDLKAFPKDN 437
TV ++ V T Y + N GK I + + + P P
Sbjct 780 TVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPDTIIGYSGEDLPSAPRRFRVRQPNLE 839
Query 438 MLWVEW---TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
+ +EW P + YIL + + + + ++ Y
Sbjct 840 TINLEWDHPEHPNGILIGYILRYVPFNGTKLGKQMVENFSPNQTKFSVQ-RADPVSRYRF 898
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
+++ G G +A +++P P
Sbjct 899 SLSARTQVGSG-----EAATEESP--APPN 921
Score = 134 bits (336), Expect = 1e-30, Method: Composition-based stats.
Identities = 59/310 (19%), Positives = 100/310 (32%), Gaps = 30/310 (10%)
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR-------WK 374
P P ++ + R+V+L W +P + N I DY V W
Sbjct 620 LAALPKGRPDRPRDLELTD-LAERSVRLTW--IPGDDNNSPITDYVVQFEEDQFQPGVWH 676
Query 375 SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP--VMDLKA 432
H + + + Y + N VG S ++ + A D+K
Sbjct 677 DHSRFPGSVNSAVLHLSPYVNYQFRVIAVNEVGSSHPSLPSERYRTSGAPPESNPSDVKG 736
Query 433 FPK-DNMLWVEWTTPR-----ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
N + + WT +YI++W + W Y+ G
Sbjct 737 EGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETRE----TWNNVT-VWGSRYVVGQT 791
Query 487 AESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
Y I V G G P++I Y + PS R ++ LEWD +
Sbjct 792 PVYVPYEIRVQAENDFGKGPEPDTIIGYSGEDLPSAPRRFRVRQPNLETINLEWDH--PE 849
Query 546 VQNGFIRNYTIFY----RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
NG + Y + Y T +G + N + T++++ + Y ++A T G
Sbjct 850 HPNGILIGYILRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRFSLSARTQVGSG 909
Query 602 DGPEFTFTTP 611
+ P
Sbjct 910 EAATEESPAP 919
Score = 103 bits (256), Expect = 4e-21, Method: Composition-based stats.
Identities = 86/417 (21%), Positives = 149/417 (36%), Gaps = 43/417 (10%)
Query 30 YISPESPVVQLHSNFTAVC------VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIIN 83
Y PE V + + C LK YI + + +
Sbjct 525 YRMPEDQVAKRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAE 584
Query 84 RTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLP---PEKPKNLSCIVNEGK 140
R S T L+ L LT L ++ LP P++P++L +
Sbjct 585 RDQGSYTCMASTELDQDLAKAYLT--VLADQATPTNRLAALPKGRPDRPRDLELTDLAER 642
Query 141 KMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSC-TVDYSTVYFVNIEVWV 198
+R W G + + T++ ++ E + P S + +VN + V
Sbjct 643 SVRLTWIPGDDNNSPITDYVVQFEEDQFQPGVWHDHSRFPGSVNSAVLHLSPYVNYQFRV 702
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHN--LSVINSEELSSILKLTWTNPSIKS--VII 254
A N +G +S Y+ PP + V + +++TWT + S
Sbjct 703 IAVNEVG--SSHPSLPSERYRTSGAPPESNPSDVKGEGTRKNNMEITWTPMNATSAFGPN 760
Query 255 LKYNIQYRTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
L+Y +++R ++ TW+ + + V + Y R++ + GKG D
Sbjct 761 LRYIVKWRRRETRETWNNVTVWGSRYVVGQTPV-----YVPYEIRVQAENDFGKGPEPD- 814
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
G + ED PS AP + P+ T+ L W P NG ++ Y + +
Sbjct 815 --TIIGYSGEDLPS-APRRFRVRQPNLE----TINLEWDH--PEHPNGILIGYILRYVPF 865
Query 374 KSH------LQNYTVNATKLTVNL--TNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
++N++ N TK +V RY +L+ R VG +AA PA +
Sbjct 866 NGTKLGKQMVENFSPNQTKFSVQRADPVSRYRFSLSARTQVGSGEAATEESPAPPNE 922
Score = 100 bits (248), Expect = 4e-20, Method: Composition-based stats.
Identities = 60/407 (15%), Positives = 113/407 (28%), Gaps = 42/407 (10%)
Query 122 SGLPPEK-PKNLSCIVNEGKKMRCEWDGGRET---HLETNFTLKSEWATHKFADCKAKRD 177
SG PPE P ++ M W T + +K W + +
Sbjct 723 SGAPPESNPSDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVK--WRRRETRETWNNVT 780
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
S V T +V E+ V+AEN GK + P+ P V
Sbjct 781 VWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPDTIIGYSGEDLPSAPRRFRVRQPNLE- 839
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ L W +P + I++ Y ++Y + + + E+ + ++ F+VQ P + Y F
Sbjct 840 -TINLEWDHPEHPNGILIGYILRYVPFNGTKLGKQMVENFSPNQTKFSVQRADPVSRYRF 898
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
+ + G G T E S AP + T
Sbjct 899 SLSARTQVGSGE---------AATEE---SPAPPNEATPTAAPPTLPPT---------TV 937
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
G + + T S + T + + T T +
Sbjct 938 GTTGLVSSTDATALAATSEATTVPIIPTVVPTTVATTIATTTTTTAATTTTTTTESPPTT 997
Query 418 A------CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
+ ++ P + W +++E+ + +
Sbjct 998 TAGTKIHETAPDEQSIWNVTVLPNSKWANITWKHNFRPGTDFVVEYIDSNHTKKTVPVKA 1057
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
Q +L Y + V +G ++ ++
Sbjct 1058 QAQPIQ-----LTDLFPGMTYTLRVYSRDNEGI--SSTVITFMTSTA 1097
>sp|P35992|PTP10_DROME Tyrosine-protein phosphatase 10D OS=Drosophila
melanogaster OX=7227 GN=Ptp10D PE=1 SV=4
Length=1990
Score = 136 bits (341), Expect = 4e-31, Method: Composition-based stats.
Identities = 98/589 (17%), Positives = 179/589 (30%), Gaps = 71/589 (12%)
Query 68 KTNHFTIPKEQYTIIN------------RTASSVTFTDIASLNIQLTCNILTFGQLEQNV 115
+ +EQY ++ S + ++ + ++
Sbjct 515 WKSDVNSKQEQYEVLYSRNGTSDLRTQKTKESRLVIKNLQ-PGAGYELKVFAVSHDLRSE 573
Query 116 YGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHK-FADCKA 174
+ P P+N++ + W E+ T ++++ + + + +
Sbjct 574 PHAYFQAVY-PNPPRNMTIETVRSNSVLVHWSP-PESGEFTEYSIRYRTDSEQQWVRLPS 631
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
R T T + V + G + + PP+ +S I
Sbjct 632 VRSTEADIT---DMTKGEKYTIQVNTV-SFGVESPVPQEVNTTV-----PPNPVSNIIQL 682
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS-------SFTVQ 287
S + L W P + Y +++ D ++ ++ + +S +
Sbjct 683 VDSRNITLEWPKPE---GRVESYILKWWPSDNPG--RVQTKNVSENKSADDLSTVRVLIG 737
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP---SFWYKIDPSHTQGY 344
+L P +Y F I+ G SGIT P P S +
Sbjct 738 ELMPGVQYKFDIQ-TTSYGI---------LSGITS-LYPRTMPLIQSDVVVANGEKEDER 786
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRN 404
T+ L + P + I + + + + K+T L +TV
Sbjct 787 DTITLSYTPTPQSSSKFDIYRFSLGDAEIRDKEKLANDTDRKVTFTGLVPGRLYNITVWT 846
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDK 463
+ G A L I D P+ L A D + + W P+ + + +
Sbjct 847 VSGG--VASLPIQRQDRLYPEPITQLHATNITDTEISLRWDLPKGEYNDFDIAYLTAD-- 902
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD-----GPGSPESIKAYLKQAP 518
+ ++ T +L + Y TV SP S +A
Sbjct 903 -----NLLAQNMTTRNEITISDLRPHRNYTFTVVVRSGTESSVLRSSSPLSASFTTNEAV 957
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY- 577
P + V +E EW LP NG IR ++I Y T I N T + +E
Sbjct 958 PGRVERFHPTDVQPSEINFEWS-LPSSEANGVIRQFSIAY-TNINNLTDAGMQDFESEEA 1015
Query 578 --TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVP 624
+ +L Y+ ++ A T G E+ T P A VVP
Sbjct 1016 FGVIKNLKPGETYVFKIQAKTAIGFGPEREYRQTMPILAPPRPATQVVP 1064
Score = 111 bits (277), Expect = 2e-23, Method: Composition-based stats.
Identities = 84/534 (16%), Positives = 168/534 (31%), Gaps = 40/534 (7%)
Query 72 FTIPKEQYTIINRT-ASSVTFTD-IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKP 129
F P+ TI +R + F+ + F + + +TI + P+ P
Sbjct 69 FGYPEPNTTIASREIGDEIQFSRALPGTKYNFWLYYTNFTHHDWLTWTVTITT--APDPP 126
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
NLS V GK W + T F +K + + +
Sbjct 127 SNLSVQVRSGKNAIILWSPPTQGS-YTAFKIKVLGLSEASSSYNRTFQVNDNTFQHSVKE 185
Query 190 YFVNIEVWVEAEN-ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
V+A GK + + + + KPN P V E + L + W P
Sbjct 186 LTPGATYQVQAYTIYDGKESVAYTSRNFT--TKPNTPGKFIVWFRNE--TTLLVLWQPP- 240
Query 249 IKSVIILKYNIQYRTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
+ I Y + DA + + E + + L P Y ++ M ED
Sbjct 241 YPAGIYTHYKVSIEPPDANDSVLYVEKEGEPPGPAQAAFKGLVPGRAYNISVQTMSED-- 298
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
+ S + Y P + + + D + +R ++W+ P +
Sbjct 299 ----EISLPTTAQ-YRTVPLRPLNVTFDRDFITSNSFR---VLWEA-PKGISEFDKYQVS 349
Query 368 VTLTRWKSHLQNYTVNATKL-TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
V TR +S + ++ + V+ + GK P
Sbjct 350 VATTRRQSTVPRSNEPVAFFDFRDIAEPGKTFNVIVKTVSGK--VTSWPATGDVTLRPLP 407
Query 427 VMDLKAFPKD--NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
V +L++ D N + + W S + E+ ++ + T +
Sbjct 408 VRNLRSINDDKTNTMIITWEADPASTQD---EYRIVYHELETFNGDTSTLTTDRTRFTLE 464
Query 485 NLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
+L + Y ++V V + SI + + P +++ ++G N + W
Sbjct 465 SLLPGRNYSLSVQAVSKKMESNETSIFVVTRPSSPI-IEDLKSIRMGLN---ISWK---- 516
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
N Y + Y ++ + + + +L Y +++ A + +
Sbjct 517 SDVNSKQEQYEVLYSRNGTSDLRTQ-KTKESRLVIKNLQPGAGYELKVFAVSHD 569
Score = 104 bits (258), Expect = 3e-21, Method: Composition-based stats.
Identities = 68/461 (15%), Positives = 136/461 (30%), Gaps = 43/461 (9%)
Query 147 DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK 206
+ G + + + A R+ + W+ N
Sbjct 52 NPGLDDGASYRLDYSPPFGYPEPNTTIASREIGDEIQFS-RALPGTKYNFWLYYTNF--- 107
Query 207 VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA 266
D + + P+PP NLSV ++I+ W+ P+ S + I+
Sbjct 108 THHDWLTWTVTITTAPDPPSNLSVQVRSGKNAIIL--WSPPTQGSY--TAFKIKVLGLSE 163
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
++ S +V++L P Y +++ G S + T + P
Sbjct 164 ASSSYNRTFQVNDNTFQHSVKELTPGATY--QVQAYT-IYDGKESVAYTSRNFTTKPNTP 220
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN--- 383
K + T+ ++W+ P G Y+V++ ++ V
Sbjct 221 GK--------FIVWFRNETTLLVLWQPPYPA---GIYTHYKVSIEPPDANDSVLYVEKEG 269
Query 384 ------ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN 437
+ Y ++ + S + + D + F N
Sbjct 270 EPPGPAQAAFKGLVPGRAYNISVQTMSEDEISLPTTAQYRTVPLRPLNVTFD-RDFITSN 328
Query 438 MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
V W P+ + ++ V + + + V R K + + V
Sbjct 329 SFRVLWEAPKGISE--FDKYQVSVATTRRQSTVPRSNEPVAFFDFRDIAEPGKTFNVIVK 386
Query 498 PVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN-EAVLEWDQLPVDVQNGFIRNYTI 556
V P + L+ P +R+ K ++ W+ P Q+ Y I
Sbjct 387 TVSGKVTSWPATGDVTLR---PLPVRNLRSINDDKTNTMIITWEADPASTQD----EYRI 439
Query 557 FYRTIIG-NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
Y + N + + T +TL SL Y + + A +
Sbjct 440 VYHELETFNGDTSTLTTDRTRFTLESLLPGRNYSLSVQAVS 480
Score = 82.2 bits (201), Expect = 2e-14, Method: Composition-based stats.
Identities = 86/570 (15%), Positives = 167/570 (29%), Gaps = 94/570 (16%)
Query 119 TIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDT 178
+ + +PP N+ + + + + EW E +E ++ LK W + + K +
Sbjct 666 EVNTTVPPNPVSNII-QLVDSRNITLEW-PKPEGRVE-SYILKW-WPSDNPGRVQTKNVS 721
Query 179 PTSCTVDYSTVYF--------VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
D STV V + ++ + G ++ + P ++ V
Sbjct 722 ENKSADDLSTVRVLIGELMPGVQYKFDIQ-TTSYGILSG---ITSLYPRTMPLIQSDVVV 777
Query 231 IN--SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
N E+ + L++T S Y ++ DA + T T
Sbjct 778 ANGEKEDERDTITLSYTPTPQSSSKFDIY--RFSLGDAEIRD--KEKLANDTDRKVTFTG 833
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
L P Y + W S + + + + P ++ + +
Sbjct 834 LVPGRLYNITV----------W-TVSGGVASLPIQRQDRLYPEPITQLH-ATNITDTEIS 881
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND--RYLATLTVRNLV 406
L W LP E N D+++ + L ++T++ Y T+ VR+
Sbjct 882 LRWD-LPKGEYN----DFDIAYLTADNLLAQNMTTRNEITISDLRPHRNYTFTVVVRSGT 936
Query 407 ------GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
S + + + + EW+ P I ++ +
Sbjct 937 ESSVLRSSSPLSASFTTNEAVPGRVERFHPTDV-QPSEINFEWSLPSSEANGVIRQFSIA 995
Query 461 SDKAPCITDWQQEDGTVHRTY-LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
+TD +D + + NL + Y+ + A G G + + P
Sbjct 996 YTNINNLTDAGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFGPEREYRQTMPILAP 1055
Query 520 SKGPTVRTKKV---GKNEAVLEWDQLPVDVQNGFIRNYTI----------------FYRT 560
+ T + + + + QNG +R YTI +
Sbjct 1056 PRPATQVVPTEVYRSSSTIQIRFRKNYFSDQNGQVRMYTIIVAEDDAKNASGLEMPSWLD 1115
Query 561 IIGNETAVNVDSSHTEYTLSS------------------------LTSDTLYMVRMAAYT 596
+ + + Y + L S T Y V++ A+T
Sbjct 1116 VQSYSVWLPYQAIDPYYPFENRSVEDFTIGTENCDNHKIGYCNGPLKSGTTYRVKVRAFT 1175
Query 597 DEG--GKDGPEFTFTTPKFAQGEIEAIVVP 624
F T + I AI VP
Sbjct 1176 GADKFTDTAYSFPIQTDQDNTSLIVAITVP 1205
>sp|Q09165|DIG1_CAEEL Mesocentin OS=Caenorhabditis elegans OX=6239
GN=dig-1 PE=1 SV=2
Length=13100
Score = 135 bits (340), Expect = 7e-31, Method: Composition-based stats.
Identities = 99/555 (18%), Positives = 164/555 (30%), Gaps = 52/555 (9%)
Query 72 FTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKN 131
IP +S+ + L C + + I P P+N
Sbjct 940 VPIPIHSDDSQPHHYNSIQVYSTTATKRILLCQARNPDGTVDDRH--VFIVNKPGSAPQN 997
Query 132 LSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADCKAKRDT-PTSCTVD 185
IV+ ++ W G T T ++ T P
Sbjct 998 PEVIVDPDNRVTITWQPPKYPNGEITSYNVYITGDPSLPVDQWQVFPVDDVTDPKLVLQR 1057
Query 186 YSTVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ V + A N G+ + +D +FD V + P + V+ S + + + +TW
Sbjct 1058 GALQPETPYFVKIAAVNPHGEGIHTDPKHFDTVSGAPIDAPTD--VLPSVSIDNTVNITW 1115
Query 245 TNPSIKSVIILKYNI----QYRTKDASTWSQIPPEDTASTRS-SFTVQD--LKPFTEYVF 297
+ P+ I Y + +Y D TW +I + T+ P T Y
Sbjct 1116 SPPTQPLGPIKSYTVYFAPEYDDSDFKTWQRISVDAPDGADHGEVTLPKEQFNPNTPYKI 1175
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
RI + +G SD +G + E P+ G T+ +P
Sbjct 1176 RISATNDLSEGPASDPVRFETG-SGEIPPTITLDPSNSTYTVEPLGAATITCTATGVPQP 1234
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
+ W +AT +L D AT N GK+ AV
Sbjct 1235 KV------------HWIKANGETVDSATLQLYDLVKDT-SATCVAENNAGKTQEAVSIQ- 1280
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQED 474
T P + + + VEWT+P + YI+ + +S+ W Q
Sbjct 1281 -VTGPGTAPNEIVLLPMPNQEINVEWTSPDEVNGQITNYIIHYGEISEDGSEPATWDQVT 1339
Query 475 GTVHRT-YLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGK 532
+ NL K Y I V V GPG P +
Sbjct 1340 IARDDVNHKLANLEPKKTYAIRVQAVSDRGPGVISAPQVIKTLPLAPQAITNPIIQVHPN 1399
Query 533 NEAVLEWDQL-PVDVQNGFIRNYTIFYRTIIGNETA------------VNVDSSHTEYTL 579
N +E+ + ++++ I Y T + D++
Sbjct 1400 NSVTIEFTPPDDPENPGKKVKDFVIQYTTDEEPDDESVWKELKFTDPDDTDDTTIVSIDG 1459
Query 580 SSLTSDTLYMVRMAA 594
+ DT Y R+ A
Sbjct 1460 ENFNPDTKYNTRIIA 1474
Score = 131 bits (330), Expect = 1e-29, Method: Composition-based stats.
Identities = 97/534 (18%), Positives = 158/534 (30%), Gaps = 79/534 (15%)
Query 126 PEKPKNLSCIV--NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P +P + C+ + W + + + + D
Sbjct 905 PTQPIHFRCVADGRPMPSVSYSWLP-----------INASESGDEPVPIPIHSDDSQPHH 953
Query 184 VDYSTVYFVNIEVWV---EAENALGKVTSDHINFDPVYKVKPN-PPHNLSVINSEELSSI 239
+ VY + +A N G V H+ KP P N VI +
Sbjct 954 YNSIQVYSTTATKRILLCQARNPDGTVDDRHVFI----VNKPGSAPQNPEVIVDPDN--R 1007
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDAS----TWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+ +TW P + I YN+ Y T D S W P +D + L+P T Y
Sbjct 1008 VTITWQPPKYPNGEITSYNV-YITGDPSLPVDQWQVFPVDDVTDPKLVLQRGALQPETPY 1066
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
+I + G+G +D T P AP+ TV + W P
Sbjct 1067 FVKIAAVNPHGEGIHTD---PKHFDTVSGAPIDAPTDVLP----SVSIDNTVNITWS--P 1117
Query 356 PFEANGKILDYEVTLTRWK-----SHLQNYTVNAT------KLTVN----LTNDRYLATL 400
P + G I Y V Q +V+A ++T+ N Y +
Sbjct 1118 PTQPLGPIKSYTVYFAPEYDDSDFKTWQRISVDAPDGADHGEVTLPKEQFNPNTPYKIRI 1177
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
+ N + + A+ P + L + + C
Sbjct 1178 SATNDLSEGPASDPVRFETGSGEIPPTITLDPSNSTYTV----EPLGAATIT-----CTA 1228
Query 461 SDKAPCITDWQQEDGTVHR--TYLRGNLAESKCYLITVTPVYADG-PGSPESIKAYLKQA 517
+ W + +G T +L + T G SI+
Sbjct 1229 TGVPQPKVHWIKANGETVDSATLQLYDLVKDT--SATCVAENNAGKTQEAVSIQVTGPGT 1286
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN------ETAVNVD 571
P++ + + E +EW D NG I NY I Y I + V +
Sbjct 1287 APNE---IVLLPMPNQEINVEW--TSPDEVNGQITNYIIHYGEISEDGSEPATWDQVTIA 1341
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPV 625
+ L++L Y +R+ A +D G G K +AI P+
Sbjct 1342 RDDVNHKLANLEPKKTYAIRVQAVSDRG--PGVISAPQVIKTLPLAPQAITNPI 1393
Score = 108 bits (269), Expect = 2e-22, Method: Composition-based stats.
Identities = 95/498 (19%), Positives = 157/498 (32%), Gaps = 68/498 (14%)
Query 199 EAENALGKVTSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSVIILKY 257
+A N+ G SD PV + P P ++ + + + W P + + I Y
Sbjct 763 QAVNSEG---SDEKKV-PVKILGPGSAPLGIT---PTPMHTGFDVAWKPPKVTNGRITDY 815
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
+ Y + S + + + TV T YV +++ +DG G S+ E
Sbjct 816 VVYYSKDPDAPLSDWESKTVPADTRNLTVNVDDEDTPYVVKVQARTDDGPGIISEAYEVT 875
Query 318 SGIT-------YEDR-PSKAPSF-WYKIDPSHTQGYR---------TVQLVWKTLPPFEA 359
+G E PS PS ++P+ +R +V W + E+
Sbjct 876 TGRKQVPLSVRLEIADPSVDPSTGETIVEPTQPIHFRCVADGRPMPSVSYSWLPINASES 935
Query 360 NGKILDYEVTLTRWK-SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
+ + + + H + V +T T + + RN G D + I
Sbjct 936 GDEPVPIPIHSDDSQPHHYNSIQVYSTTATKRILLCQ------ARNPDGTVDDRHVFIVN 989
Query 419 CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCIT--DWQQEDGT 476
A + DN + + W P + I + V P + WQ
Sbjct 990 KPGSAPQNPEVI--VDPDNRVTITWQPP-KYPNGEITSYNVYITGDPSLPVDQWQVFPVD 1046
Query 477 VHR----TYLRGNLAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPSKGPTVRTKKVG 531
RG L Y + + V G G + P PT V
Sbjct 1047 DVTDPKLVLQRGALQPETPYFVKIAAVNPHGEGIHTDPKHFDTVSGAPIDAPTDVLPSVS 1106
Query 532 -KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-----ETAVNVDSS----HTEYTLSS 581
N + W P G I++YT+++ + ++VD+ H E TL
Sbjct 1107 IDNTVNITWS--PPTQPLGPIKSYTVYFAPEYDDSDFKTWQRISVDAPDGADHGEVTLPK 1164
Query 582 --LTSDTLYMVRMAAYTDEGGKD---------GPEFTFTTPKFAQGEIEAIVVPVCLAFL 630
+T Y +R++A D G T V P+ A +
Sbjct 1165 EQFNPNTPYKIRISATNDLSEGPASDPVRFETGSGEIPPTITLDPSNSTYTVEPLGAATI 1224
Query 631 LTTLLGVLFCFNKRDLIK 648
T GV K IK
Sbjct 1225 TCTATGVP--QPKVHWIK 1240
Score = 92.6 bits (228), Expect = 1e-17, Method: Composition-based stats.
Identities = 63/382 (16%), Positives = 107/382 (28%), Gaps = 50/382 (13%)
Query 169 FADCKAKRDTPTSCTVDYSTVY-----FVNIEVWVEAENALGKVTSDHINFDPVYKVKPN 223
F + K D P T+ S + + N E ++N G V V
Sbjct 340 FKNQKVNTDGPDQNTLRASQILIIKEIYRNEEFTCVSDNIHGSAN------RTVSIVVTG 393
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P + ++ + L + W PSI + I Y + Y +
Sbjct 394 PGSAPHLKSASAGRTSLTVRWEPPSIINRPITTYTLYYTNNPQQPVKNWKKLEVKEPTRE 453
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWS---------DWSEEASGITYEDRPSKAPSFWY 334
+ DL+P T Y R+R G G I D P +
Sbjct 454 VAIPDLRPDTAYYIRVRANDPLGPGKLGNQVQIKTLKPAVRPYVNIVEGDEIRVPPMTAF 513
Query 335 KIDPSHTQGYRTVQLVW--KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT 392
+ID + T+ LVW K P + + T+ + +T+ +
Sbjct 514 EIDCNVTRADPVPVLVWLHKGRPLNKG---------SKTQHIKMKNGGVLESTQFSC--- 561
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR---ES 449
N GKS + ++ + + ++W P+
Sbjct 562 --------VAENEAGKSTKKI----NVTVTGPSAPERIRYQIDGDKVTLQWEPPQITNGP 609
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES 509
+ Y + + D RT L E Y + GPG P +
Sbjct 610 MAGYDVFYTEDPSLPRDQWKVHHIDDPNARTTTVLRLNEKTPYTFVIVGRNRLGPGLPSA 669
Query 510 IKAYLKQAPPSKGPTVRTKKVG 531
+K P V+ +
Sbjct 670 PFTATTWLA-AKPPVVQLEPSE 690
Score = 91.8 bits (226), Expect = 2e-17, Method: Composition-based stats.
Identities = 90/555 (16%), Positives = 173/555 (31%), Gaps = 84/555 (15%)
Query 119 TIISGLPPEKPKNLSCIVNEGKKMRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRD 177
TI P P+N+ N+ + +++ + + + + D + +
Sbjct 1576 TIFVAGPGTAPENIQLTANKPTTISVQYEVPSIPNGNISKYIIYYTPLDDQDPDHQLGQV 1635
Query 178 TPTSCTVDYSTVYFVN--------------------IEVWVEAENALGKVT-SDHINFDP 216
+ D+ V+ +N V V+A N G S+
Sbjct 1636 QTKPIS-DWQNVHDMNDGVEGPRKVDIKDFVSTDTAYAVVVQAINDDGPGPYSNQYTIRT 1694
Query 217 VYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS--------- 267
+ + + PP L V + S++ + W P V + Y I Y D S
Sbjct 1695 MSRAREGPPVELRVEPDGQRSAVAQ--WKEPVTSDVPPIGYEIYYVRGDKSVEEDDSAGL 1752
Query 268 -TWSQIPPEDTASTRSSFTVQDLK-PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
W +I +D T+ + +Q+L P T+YVF++R + DG S +SE T D
Sbjct 1753 NDWIKISIDD--PTKLTHKIQNLLLPDTDYVFKMRAIYPDG---PSVFSEPCIMKTLPD- 1806
Query 326 PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ------- 378
AP + +G T+Q++ + +W
Sbjct 1807 -GNAPYIQISTGDNGVEGSTTIQIL--PGSQMTIACNATGIPLPQVKWIKAGNYEIDPSR 1863
Query 379 -NYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK 435
+ N + ++ + N + +N +G ++ + + + +
Sbjct 1864 VDADGNHAQFSLQVANITEDTTFNCVAQNPLGHANWTINVNLIEGLEPNWRDDFVTSKSD 1923
Query 436 DNMLWVEWT--------TPRESVKKYILEWCVLSDKAPCITDWQQED--GTVHRTYLRGN 485
+ + + P E +Y D W+ G N
Sbjct 1924 GGQIVLVFNDELPEYLKPPNEWTIQY------TDDAEQPKDQWESIPSGGAPLTRVEVPN 1977
Query 486 LAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
+ Y + V G +P + P +R K +E ++++
Sbjct 1978 MNPGTFYYLVVDN-PEKGIQTPTLVVMT-----PKPPSDIRFGKNNDDEQIVDFKPAVAS 2031
Query 546 VQNGFIRNYTIF-YRTIIGNETA--VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
I+ YTI + + + + + L DT Y V++AA EG +
Sbjct 2032 EP---IKEYTISVWPSTDPSNVKKFTTPADVTSGVVVDGLEPDTEYNVQVAAEFYEGEEL 2088
Query 603 GPE-FTFTTPKFAQG 616
E T TP
Sbjct 2089 ASEPVTVKTPPRDVS 2103
Score = 64.5 bits (155), Expect = 5e-09, Method: Composition-based stats.
Identities = 49/291 (17%), Positives = 86/291 (30%), Gaps = 36/291 (12%)
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR--------WKSHLQNYTVNATKLTVN 390
S + G ++ + W+ PP N I Y + T WK +
Sbjct 402 SASAGRTSLTVRWE--PPSIINRPITTYTLYYTNNPQQPVKNWKKLEVKEPTREVAIPDL 459
Query 391 LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA-----FPKDNMLWVEWTT 445
+ Y + + +G A P +++ P ++
Sbjct 460 RPDTAYYIRVRANDPLGPGKLGNQVQIKTLKPAVRPYVNIVEGDEIRVPPMTAFEIDCNV 519
Query 446 PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
R +L W + T H G + ES + G
Sbjct 520 TRADPVP-VLVWLHKGRPL------NKGSKTQHIKMKNGGVLEST--QFSCVAENEAGK- 569
Query 506 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-- 563
S + I + PS +R ++ ++ L+W+ P + NG + Y +FY
Sbjct 570 STKKINVTV--TGPSAPERIR-YQIDGDKVTLQWE--PPQITNGPMAGYDVFYTEDPSLP 624
Query 564 --NETAVNVDS-SHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTT 610
++D + T+ L T Y + G G FT TT
Sbjct 625 RDQWKVHHIDDPNARTTTVLRLNEKTPYTFVIVGRNRLGPGLPSAPFTATT 675
Score = 63.0 bits (151), Expect = 2e-08, Method: Composition-based stats.
Identities = 27/125 (22%), Positives = 44/125 (35%), Gaps = 10/125 (8%)
Query 493 LITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
T G + P P +++ G+ + W+ P + N I
Sbjct 371 EFTCVSDNIHGSANRTVSIVVTG---PGSAPHLKSASAGRTSLTVRWE--PPSIINRPIT 425
Query 553 NYTIFY----RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFT 607
YT++Y + + N + V E + L DT Y +R+ A G GK G +
Sbjct 426 TYTLYYTNNPQQPVKNWKKLEVKEPTREVAIPDLRPDTAYYIRVRANDPLGPGKLGNQVQ 485
Query 608 FTTPK 612
T K
Sbjct 486 IKTLK 490
>sp|Q92673|SORL_HUMAN Sortilin-related receptor OS=Homo sapiens
OX=9606 GN=SORL1 PE=1 SV=2
Length=2214
Score = 135 bits (339), Expect = 8e-31, Method: Composition-based stats.
Identities = 81/481 (17%), Positives = 155/481 (32%), Gaps = 45/481 (9%)
Query 128 KPKNLSCIVNEGKKMRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
K +NL + + W + + + T+ +
Sbjct 1557 KVQNLQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTNTVLKV 1616
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDP-VYKVKPNPPHNLSVINSEELSSILKLTWT 245
+V V+ + L K + + + P+ P NL + E ++ W
Sbjct 1617 LKP-DTTYQVKVQVQ-CLSKAHNTNDFVTLRTPEGLPDAPRNLQLSLPREAEGVIVGHWA 1674
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P +I +Y ++Y + W+ + +++L T Y R+ +
Sbjct 1675 PPIHTHGLIREYIVEYSRSGSKMWASQRAASNFT-----EIKNLLVNTLYTVRVAAVTSR 1729
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G G WSD S T + + P S+ + Y + L E++ K+
Sbjct 1730 GIGNWSD---SKSITTIKGKVIPPPDIHID---SYGENYLSFTLT------MESDIKVNG 1777
Query 366 YEVT-LTRWKSHLQN-------YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
Y V + +H Q ++ + K+ + Y + + +G S A +
Sbjct 1778 YVVNLFWAFDTHKQERRTLNFRGSILSHKVGNLTAHTSYEISAWAKTDLGDSPLAFEHVM 1837
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
+ P + KA + + WT PR V Y + +
Sbjct 1838 TRGVRPPAPSLKAKAINQ-TAVECTWTGPRNVV--YGIFYATSFLDLYRNPKSLTTSLHN 1894
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP--TVRTKKVGKNEA 535
+ ++ + YL V V P S +K P S+ P + GK
Sbjct 1895 KTVIV----SKDEQYLFLVRVVVP--YQGPSSDYVVVKMIPDSRLPPRHLHVVHTGKTSV 1948
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNET---AVNVDSSHTEYTLSSLTSDTLYMVRM 592
V++W+ P D + + Y + + +I V +S EYTL+ L Y + +
Sbjct 1949 VIKWES-PYDSPDQDLL-YAVAVKDLIRKTDRSYKVKSRNSTVEYTLNKLEPGGKYHIIV 2006
Query 593 A 593
Sbjct 2007 Q 2007
Score = 114 bits (284), Expect = 3e-24, Method: Composition-based stats.
Identities = 98/629 (16%), Positives = 192/629 (31%), Gaps = 64/629 (10%)
Query 45 TAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSV-TFTDIASLNIQLTC 103
+A CV + ++ +I K T N+T + + + +++
Sbjct 1583 SASCVY-------------NVYYRVVGESIWKTLETHSNKTNTVLKVLKPDTTYQVKVQV 1629
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVN-EGKKMRC-EWDGGRETH-LETNFTL 160
L+ + + GL P+ P+NL + E + + W TH L + +
Sbjct 1630 QCLSKAHNTNDFVTLRTPEGL-PDAPRNLQLSLPREAEGVIVGHWAPPIHTHGLIREYIV 1688
Query 161 KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYK 219
+ + K + T + + V V A + G SD + + K
Sbjct 1689 EYSRSGSKMWASQRAASNFTEI---KNLLVNTLYTVRVAAVTSRGIGNWSDSKSITTI-K 1744
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
K PP ++ + + E LT + + Y + + + +
Sbjct 1745 GKVIPPPDIHIDSYGENYLSFTLT----MESDIKVNGYVVNLFWAFDTHKQERRTLNFRG 1800
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
+ S V +L T Y + G +T RP I+ +
Sbjct 1801 SILSHKVGNLTAHTSYEISAWAKTDLGDSPL----AFEHVMTRGVRPPAPSLKAKAINQT 1856
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT 399
V+ W P G + Y + + ++ T + TV ++ D
Sbjct 1857 ------AVECTWTG-PRNVVYG--IFYATSFLDLYRNPKSLTTSLHNKTVIVSKDEQYLF 1907
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRESVKKYILEWC 458
L + + ++ + + P L + ++W +P +S + +L +
Sbjct 1908 LVRVVVPYQGPSSDYVVVKMIPDSRLPPRHLHVVHTGKTSVVIKWESPYDSPDQDLL-YA 1966
Query 459 VLSDKAPCITD--WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
V TD ++ + Y L Y I V SIK
Sbjct 1967 VAVKDLIRKTDRSYKVKSRNSTVEYTLNKLEPGGKYHIIVQLGNMS---KDSSIKITT-- 2021
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN-GFIRNYTIFYRTIIGNETAVNVDSSHT 575
P + +L W L + ++ R Y I N TA +++
Sbjct 2022 -VSLSAPDALKIITENDHVLLFWKSLALKEKHFNESRGYEIHMFDSAMNITAYLGNTTDN 2080
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF-------------TTPKFAQGEIEAIV 622
+ +S+L Y + A G + E T ++ A+V
Sbjct 2081 FFKISNLKMGHNYTFTVQARCLFGNQICGEPAILLYDELGSGADASATQAARSTDVAAVV 2140
Query 623 VPVCLAFLLTTLLGVLFCFNKRDLIKKHI 651
VP+ LL+ +G + K ++
Sbjct 2141 VPILFLILLSLGVGFAILYTKHRRLQSSF 2169
Score = 89.5 bits (220), Expect = 1e-16, Method: Composition-based stats.
Identities = 81/515 (16%), Positives = 163/515 (32%), Gaps = 56/515 (11%)
Query 323 EDRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTLTR-----WKSH 376
E S + + + T + V L W + + Y V WK+
Sbjct 1546 EKACSDELTVYKVQNLQWTADFSGDVTLTWMRPKKMPSASCV--YNVYYRVVGESIWKTL 1603
Query 377 LQNYTVNATKLTVNLTNDRYLATLTVRN-LVGKSDAAVLTIPACDFQATHPVMDLKAFPK 435
+ T L V + Y + V+ + +T+ + P + P+
Sbjct 1604 ETHSNKTNTVLKVLKPDTTYQVKVQVQCLSKAHNTNDFVTLRTPEGLPDAPRNLQLSLPR 1663
Query 436 D--NMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
+ ++ W P +++YI+E+ S + Q+ NL +
Sbjct 1664 EAEGVIVGHWAPPIHTHGLIREYIVEY---SRSGSKMWASQRAASNFTEIK---NLLVNT 1717
Query 491 CYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKN--EAVLEWDQLPVDVQ 547
Y + V V + G G+ +S + P + G+N L
Sbjct 1718 LYTVRVAAVTSRGIGNWSDSKSITTIKGKVIPPPDIHIDSYGENYLSFTLT------MES 1771
Query 548 NGFIRNYTIF----YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ + Y + + T +N S + + +LT+ T Y + A TD G
Sbjct 1772 DIKVNGYVVNLFWAFDTHKQERRTLNFRGSILSHKVGNLTAHTSYEISAWAKTDLGDSPL 1831
Query 604 PEFTFTT-------PKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVP 656
T P I V + G+ + + DL + P
Sbjct 1832 AFEHVMTRGVRPPAPSLKAKAINQTAVECTWTGPRNVVYGIFYATSFLDLYRN------P 1885
Query 657 DPSKSHIAQWSPHTPPRHNFNSKDQ--MYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLF 714
+ + + + + + G +D VV++ + + P P L +
Sbjct 1886 KSLTTSLHNKTVIVSKDEQYLFLVRVVVPYQGPSSDYVVVKMIPDSRLP-PRHLHVVHTG 1944
Query 715 KKEKINTEGHSSGIGGSSCM--SSSRPSISSSDENESSQNTSSTVQYS--TVVHSGYRHQ 770
K + + + + I +D + ++ +STV+Y+ + G H
Sbjct 1945 KTSVVIKWESPYDSPDQDLLYAVAVKDLIRKTDRSYKVKSRNSTVEYTLNKLEPGGKYHI 2004
Query 771 VPSVQVFSRSESTQPLLDSEERPEDLQLV---DHV 802
+ + S+ S + S P+ L+++ DHV
Sbjct 2005 IVQLGNMSKDSSIKITTVSLSAPDALKIITENDHV 2039
>sp|Q91289|FINC_PLEWA Fibronectin (Fragment) OS=Pleurodeles waltl
OX=8319 PE=2 SV=1
Length=1328
Score = 134 bits (338), Expect = 8e-31, Method: Composition-based stats.
Identities = 100/676 (15%), Positives = 201/676 (30%), Gaps = 72/676 (11%)
Query 85 TASSVTFTDIA-SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
+ +S+T T++ ++ + Q + G + P NL + M
Sbjct 346 SRNSLTLTNLTPGTEYVVSIFAVNGRQESVPLVGQQATVS---DTPTNLEVTSSTPTSMS 402
Query 144 CEWDGGRETHLETNFT---LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
WD T E +F + D P + + V A
Sbjct 403 ISWDAPPVGVRYYRITYTETGGETPVQEFTVPGDRSDAPIRGLKPGAE-----YIITVYA 457
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQ 260
G + +K + P L V + ++ S +++ W S + Y +
Sbjct 458 VTGRGDSPASSKPVTVTHKTVVDKPTQLQVTDVQDHS--IQVRWMP---SSTPVTGYRVT 512
Query 261 YRTKDA--STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
K T S + P D ++ T++ L+P EYV + ++G+ +
Sbjct 513 SVPKSGVGPTVSHVVPPD----QTEMTIEGLEPTVEYVVSVYAQGKNGETEP----LVET 564
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL- 377
+T DRP +D +++LVW++ G++ Y+VT + + +
Sbjct 565 AVTNIDRPKGLAFTEVDVD--------SLKLVWESPK-----GQVTTYKVTYSNPEDGIH 611
Query 378 -----QNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK- 431
N + +L Y ++ + +S + A P +L
Sbjct 612 ELVPAPNGDEDTAQLHGLRPGAEYTVSVVALHDDMESQP----LIGTQVTAIPPPTNLLF 667
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
+ + V W P + Y + V + + G L +
Sbjct 668 SQITPTSVTVSWRPPNVQLTGYRV--RVHPKEKAGPMKEINLSPDSTSAVVTG-LMVATK 724
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
Y ++V + P ++ S R V + + W + I
Sbjct 725 YEVSVYALKDSLTSRPAQGIVTTQENV-SPPRRRRITDVTETTVTITWR-TKTET----I 778
Query 552 RNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ I N + Y ++ L T Y + + D TT
Sbjct 779 TGFHIDAIPAGGQNPIQRTISPDLRTYVITGLQPGTDYKIHIYTLNDNARSSPVTIDATT 838
Query 611 PKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHT 670
+ + LTT L + K + + + + P
Sbjct 839 AVDSPSNLR----------FLTTTSNSLLFSWQPPRSKLTGYIIKYEKPGGPVREVVPRP 888
Query 671 PPRHNFNSKDQMYSDGNFTDVSVVEIEANDKK-PFPEDLKSLDLFKKEKINTEGHSSGIG 729
P + + Q G + ++ + +N K P ++ +L + + G I
Sbjct 889 HPGATESQQSQNLEPGTEYTIYIIAVRSNYKSGPLVGKKRTDELPRLVTLAQPGQQGRIL 948
Query 730 GSSCMSSSRPSISSSD 745
+ + P IS +
Sbjct 949 DVPSLVENTPFISQTS 964
Score = 128 bits (320), Expect = 1e-28, Method: Composition-based stats.
Identities = 103/694 (15%), Positives = 207/694 (30%), Gaps = 66/694 (10%)
Query 118 ITIISGLPPEKPKNLSCI-VNEGKKMRCEWDGGRETHL-----ETNFTLKSEWATHKFAD 171
IT P P +L + + W + T L + +
Sbjct 7 ITRTVVTPISPPTDLHLEPSPDFATLTVSWSRSPSPGITGYRINTALLLGIRLHSGYTLE 66
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVI 231
+ C D + +E V + S+ I +V P +
Sbjct 67 EEVTESQSRVCIFDNLS---PGVEYNVSVVSVKDDQESEPIWKTITQEV----PSLTDLN 119
Query 232 NSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ + + L WT + I+ Y + S I + T+ + V L+P
Sbjct 120 FVDVTDTSIDLRWTPLKGPT--IIGYRVTVVAAGESV--PIYEDKVGPTQGYYKVSGLEP 175
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
+Y + + DG+ S + T + P+ + + P ++ + W
Sbjct 176 GIDYDISVITLVTDGE------SAPTTLTTADCCPTATDLRFTNVGPD------SMLVTW 223
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT--KLTVNLTNDRYLATLTVRNLVGKS 409
P + ++ Y + + + + LT L Y+ ++ V +
Sbjct 224 SAPPSMVLSSFLVRYVPSKNEEDAAELTISPSDNMVVLTNLLPGTEYIVSVFA---VYEE 280
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITD 469
+ P + + V W PR +V Y +++ +
Sbjct 281 RESTPLTGVQRTGLDSPTGLDFSDTTSSSFTVYWMAPRATVTGYKIQY--HPETGGAGQK 338
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-TVRTK 528
++ + NL Y++++ V G ES+ +QA S P +
Sbjct 339 EERCVPPSRNSLTLTNLTPGTEYVVSIFAVN----GRQESVPLVGQQATVSDTPTNLEVT 394
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDT 586
+ WD PV +R Y I Y G V ++ + L
Sbjct 395 SSTPTSMSISWDAPPVG-----VRYYRITYTETGGETPVQEFTVPGDRSDAPIRGLKPGA 449
Query 587 LYMVRMAAYTDEGGKDGPEFTFT----TPKFAQGEIEAI-VVPVCLAFLLTTLLGVLFCF 641
Y++ + A T G T T +++ V + + +
Sbjct 450 EYIITVYAVTGRGDSPASSKPVTVTHKTVVDKPTQLQVTDVQDHSIQVRWMPSSTPVTGY 509
Query 642 NKRDLIKKHIWPNV-----PDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEI 696
+ K + P V PD ++ I P + ++ + + +V I
Sbjct 510 RVTSVPKSGVGPTVSHVVPPDQTEMTIEGLEPTVEYVVSVYAQGKNGETEPLVETAVTNI 569
Query 697 EANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSST 756
+ K +D K + +G + + ++ S P + + T
Sbjct 570 --DRPKGLAFTEVDVDSLKLVWESPKGQVT----TYKVTYSNPEDGIHELVPAPNGDEDT 623
Query 757 VQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSE 790
Q + G + V V + ES QPL+ ++
Sbjct 624 AQLHG-LRPGAEYTVSVVALHDDMES-QPLIGTQ 655
Score = 124 bits (310), Expect = 2e-27, Method: Composition-based stats.
Identities = 72/476 (15%), Positives = 138/476 (29%), Gaps = 47/476 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGR--ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
+ P L W R T + + ++ A K C + T
Sbjct 295 DSPTGLDFSDTTSSSFTVYWMAPRATVTGYKIQYHPETGGAGQKEERCVPPSRNSLTLT- 353
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ V + A N G+ S + + P NL V + + + ++W
Sbjct 354 --NLTPGTEYVVSIFAVN--GRQESVPLV--GQQATVSDTPTNLEVTS--STPTSMSISW 405
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
P V + Y I Y T + RS ++ LKP EY+ + +
Sbjct 406 DAP---PVGVRYYRITYTETGGET--PVQEFTVPGDRSDAPIRGLKPGAEYIITVYAVTG 460
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
G S + T D+P+ ++ + Q ++Q+ W +
Sbjct 461 RGDSPASSKPVTVTHKTVVDKPT-------QLQVTDVQD-HSIQVRWMPSST-----PVT 507
Query 365 DYEVTLTRWKSHLQNYTV----NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
Y VT + + T++T+ ++V + L A
Sbjct 508 GYRVTSVPKSGVGPTVSHVVPPDQTEMTIEGLEPTVEYVVSVYAQGKNGETEPLVETAVT 567
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ D++ V W +P+ V Y + + D + D T
Sbjct 568 NIDRPKGLAFTEVDVDSLKLV-WESPKGQVTTYKVTYSNPEDGIHELVPAPNGD---EDT 623
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
L Y ++V ++ D + + ++ + W
Sbjct 624 AQLHGLRPGAEYTVSVVALHDD---MESQPLIGTQVTAIPPPTNLLFSQITPTSVTVSWR 680
Query 541 QLPVDVQNGFIRNY--TIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
N + Y + + G +N+ T ++ L T Y V + A
Sbjct 681 PP-----NVQLTGYRVRVHPKEKAGPMKEINLSPDSTSAVVTGLMVATKYEVSVYA 731
>sp|P28192|PTP4_CAEEL Tyrosine-protein phosphatase 4 OS=Caenorhabditis
elegans OX=6239 GN=ptp-4 PE=2 SV=3
Length=1159
Score = 134 bits (336), Expect = 1e-30, Method: Composition-based stats.
Identities = 81/469 (17%), Positives = 154/469 (33%), Gaps = 64/469 (14%)
Query 145 EW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENA 203
W GR + +TL+ + C ++ ++
Sbjct 84 WWVSDGRYQLIRPFYTLRVS-------PVTPEDSGTYRCRLETDPLF------------- 123
Query 204 LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT-NPSIKSVIILKYNIQYR 262
+ VKP P + + + + L WT N + IL++++ R
Sbjct 124 --SSPQSTATQELAVMVKPVAPSSPEIKTF--TNRSITLVWTHNAARAHRPILRFSVSVR 179
Query 263 TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
T +T + S ++ V +L P+T Y F +R G SD+ E + T
Sbjct 180 TVSDNTRFVMA---APSNATTVIVDNLSPYTLYAFSVRAENSAGS---SDFGPETTFRTL 233
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
+ P++ P + + T+ PP E NG++ Y V + +
Sbjct 234 GESPNRPPQIQKIRNITSECVEVTIT------PPDEMNGELDKYLVLIQAVNETIPRKMT 287
Query 383 ----NATKLTV--NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-- 434
+T LT+ + Y + N G S A L D + P
Sbjct 288 FDKPTSTPLTICALSPSTDYALAIEADNGFGTSPQATLVFHTEDSVPNWSPSTITTLPVV 347
Query 435 KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ----QEDGTVHRTYLR----GNL 486
+ V W P + + ++++ L KA W+ ++ L +L
Sbjct 348 GKPEITVLWPAPPLNATEKVIKY-HLYYKAKNEDQWKIEHLNVSPNGVKSKLFKYRLVDL 406
Query 487 AESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG---KNEAVLEWDQLP 543
+ Y I V+ G G+ + + Q + TV K + KN L W+ P
Sbjct 407 NPNTQYRIRVSASTIKGEGAQSADS--VAQTDVGEPGTVTFKDLNFDCKNGVKLRWNYEP 464
Query 544 VDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+T+ + T++ +++ + L+ Y +R+
Sbjct 465 SVNSKKSPT-FTVK---VTNQTTSLQFNTTMLSLDIIDLSLYDEYTLRI 509
Score = 98.8 bits (244), Expect = 1e-19, Method: Composition-based stats.
Identities = 65/368 (18%), Positives = 130/368 (35%), Gaps = 51/368 (14%)
Query 290 KPFTEYVFRIRCMKEDGKGYW--------------SDWSEEASGITYEDRPSKAPSFWYK 335
+PF Y R+ + + G + S ++E + + PS
Sbjct 95 RPF--YTLRVSPVTPEDSGTYRCRLETDPLFSSPQSTATQELAVMVKPVAPSSPE----- 147
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ---NYTVNATKLTVNLT 392
T R++ LVW T A+ IL + V++ + + NAT + V+
Sbjct 148 ---IKTFTNRSITLVW-THNAARAHRPILRFSVSVRTVSDNTRFVMAAPSNATTVIVDNL 203
Query 393 N--DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP--KDNMLWVEWTTPRE 448
+ Y ++ N G SD T ++ + ++ + V T P E
Sbjct 204 SPYTLYAFSVRAENSAGSSDFGPETTFRTLGESPNRPPQIQKIRNITSECVEVTITPPDE 263
Query 449 S---VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
+ KY++ +++ P + + T L+ S Y + + G
Sbjct 264 MNGELDKYLVLIQAVNETIPRKMTFDKPTSTPLTICA---LSPSTDYALAIEADNGFGTS 320
Query 506 SPESIKAYLKQAPPSKGPTV--RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
++ + + + P+ P+ VGK E + W P + Y ++Y+
Sbjct 321 PQATLVFHTEDSVPNWSPSTITTLPVVGKPEITVLW-PAPPLNATEKVIKYHLYYKAKNE 379
Query 564 NETAVN--------VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ 615
++ + V S +Y L L +T Y +R++A T +G +G + + +
Sbjct 380 DQWKIEHLNVSPNGVKSKLFKYRLVDLNPNTQYRIRVSASTIKG--EGAQSADSVAQTDV 437
Query 616 GEIEAIVV 623
GE +
Sbjct 438 GEPGTVTF 445
>sp|Q92752|TENR_HUMAN Tenascin-R OS=Homo sapiens OX=9606 GN=TNR
PE=1 SV=3
Length=1358
Score = 133 bits (334), Expect = 3e-30, Method: Composition-based stats.
Identities = 91/578 (16%), Positives = 182/578 (31%), Gaps = 60/578 (10%)
Query 49 VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLN-IQLTCNILT 107
+ K + A + + ++ ++Y ++ T + + ++ I T
Sbjct 594 IDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATL 653
Query 108 FGQLEQNVYGITIIS--GLPPEKPKNLSCIVN--EGKKMRCEWDGGRETHLETNFTLKSE 163
+ YG+ I + P ++ + + ET + +T S
Sbjct 654 TDLVPGTEYGVGISAVMNSQQSVPATMNARTELDSPRDLMVT--ASSETSISLIWTKASG 711
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFV--------NIEVWVEAENALGKVTSDHINFD 215
H + TV + + V AE G+ S D
Sbjct 712 PIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAER--GRQQSLESTVD 769
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPE 275
+P + S SS + +TW++PS + ++ + Y +D ++
Sbjct 770 AFTGFRPIS----HLHFSHVTSSSVNITWSDPSPPADRLI---LNYSPRDEE--EEMMEV 820
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
+T+ + L+P TEY+ + + G + SE G P
Sbjct 821 SLDATKRHAVLMGLQPATEYIVNLVAV----HGTVT--SEPIVGSITTGI--DPPKDITI 872
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV---NATKLTVNLT 392
+ + +V + W Y V+ + + +V T+ T+
Sbjct 873 SNVTKD----SVMVSWSPPVASFDY-----YRVSYRPTQVGRLDSSVVPNTVTEFTITRL 923
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
N +++ ++ G+ ++ + +PV + ++W P V+
Sbjct 924 NPATEYEISLNSVRGREESERIC-TLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVEN 982
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
Y++ + I DG L L S Y T+ S
Sbjct 983 YVIVLTHFAVAGETIL----VDGVSEEFRLVD-LLPSTHYTATMYATNGPLTSGTISTNF 1037
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS 572
PP+ + +V + A++ W + I NY + Y++ G+ + VD+
Sbjct 1038 STLLDPPA---NLTASEVTRQSALISWQPPRAE-----IENYVLTYKSTDGSRKELIVDA 1089
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
T L L +T Y V + A D FTT
Sbjct 1090 EDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTT 1127
Score = 125 bits (313), Expect = 7e-28, Method: Composition-based stats.
Identities = 83/550 (15%), Positives = 165/550 (30%), Gaps = 62/550 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
P++L + + EWDG T + + + + + S
Sbjct 327 APPEDLRVAGISDRSIELEWDG---PMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTIT 383
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ + V A V S+ ++ KV + + + +++ W
Sbjct 384 ELEPGLTYNISVYA------VISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEP 437
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
S + I + K+ S +SF LKP EY+ + +KE
Sbjct 438 ---FSFSFDGWEISFIPKNNEG---GVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQA 491
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
+ + S P+ D S T + W P + + +L Y
Sbjct 492 RSPPTSASVSTVI--------DGPTQILVRDVSDTVA----FVEWIP-PRAKVDFILLKY 538
Query 367 EVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
+ ++ +V RY +++ +SD+A +
Sbjct 539 GLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTT---EID 595
Query 425 HPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
P L +EW V++Y + + L+ + + G R L
Sbjct 596 APKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATL-T 654
Query 485 NLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
+L Y + ++ V P ++ A + P + + L W
Sbjct 655 DLVPGTEYGVGISAVMNSQQSVPATMNARTELDSPR---DLMVTASSETSISLIW----- 706
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
+G I +Y I + G + V V T YTL+ L Y++ + A + G +
Sbjct 707 TKASGPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTA--ERGRQQSL 764
Query 605 EFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIA 664
E T + + + + ++ + + W + P+ I
Sbjct 765 ESTV-----DAFTGFRPISHLHFSHVTSSSVNIT-------------WSDPSPPADRLIL 806
Query 665 QWSPHTPPRH 674
+SP
Sbjct 807 NYSPRDEEEE 816
Score = 70.3 bits (170), Expect = 7e-11, Method: Composition-based stats.
Identities = 37/213 (17%), Positives = 71/213 (33%), Gaps = 14/213 (7%)
Query 420 DFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
D A P DL+ D + +EW P +V +Y++ + A QQ
Sbjct 322 DCSAVAPPEDLRVAGISDRSIELEWDGPM-AVTEYVISY---QPTALGGLQLQQRVPGDW 377
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
L Y I+V V ++ P + K + P ++ K + + ++
Sbjct 378 SGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQG---LQFKTITETTVEVQ 434
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNETAV-NVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
W+ + I + + V S T + + L Y+V + A +
Sbjct 435 WEPFSFSFD-----GWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKE 489
Query 598 EGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFL 630
+ + +T +I V +AF+
Sbjct 490 QARSPPTSASVSTVIDGPTQILVRDVSDTVAFV 522
>sp|Q62413|EPHA6_MOUSE Ephrin type-A receptor 6 OS=Mus musculus
OX=10090 GN=Epha6 PE=1 SV=2
Length=1035
Score = 133 bits (333), Expect = 3e-30, Method: Composition-based stats.
Identities = 54/239 (23%), Positives = 87/239 (36%), Gaps = 20/239 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH-----LETNFTLKSEWATHKFADCKA----- 174
PP P+N++ +NE + EW +T + K T + DC
Sbjct 330 PPSAPRNVAFNINE-TALILEWSPPSDTGGRKDLTYSVICKKCGLDTTQCEDCGGGLRFI 388
Query 175 --KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP-NPPHNLSVI 231
+ V V VN +EA N + +++ F + + P + ++
Sbjct 389 PRHTGLINNSVVVLDFVSHVNYTFEIEAMNGVSELSISPKPFTAITVTTDHDAPSLIGMM 448
Query 232 NSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ S L L+W P+ + IL Y I+Y K+ Q+ T S S V LK
Sbjct 449 RKDWASQNSLALSWQAPAFSNGAILDYEIKYYEKEHE---QLTYSSTRSKAPSVIVTGLK 505
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
P T Y+F IR G +S E +G E A + + G T+ +
Sbjct 506 PATTYIFHIRVRTATGYSGYSQKFEFETG--DETSDMAAEQGQILVIATAAVGGFTLLV 562
Score = 84.9 bits (208), Expect = 2e-15, Method: Composition-based stats.
Identities = 47/291 (16%), Positives = 84/291 (29%), Gaps = 27/291 (9%)
Query 380 YTVNATKLTVNLTNDRYLATLTV-RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
+ N + Y+ +V G A + ++ +
Sbjct 286 FAGNTKCSKCPPHSSTYVEATSVCHCEKGYFRAEKDPPSMACTRPPSAPRNVAFNINETA 345
Query 439 LWVEWTTPRESVKKYILEWCVL-----------SDKAPCITDWQQEDGTVHRTYLRGNLA 487
L +EW+ P ++ + L + V+ D + + G ++ + + +
Sbjct 346 LILEWSPPSDTGGRKDLTYSVICKKCGLDTTQCEDCGGGLRFIPRHTGLINNSVVVLDFV 405
Query 488 ESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
Y + + S I PS +R +N L W
Sbjct 406 SHVNYTFEIEAMNGVSELSISPKPFTAITVTTDHDAPSLIGMMRKDWASQNSLALSWQA- 464
Query 543 PVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
NG I +Y I +Y T + S ++ L T Y+ + T G
Sbjct 465 -PAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIVTGLKPATTYIFHIRVRTATGYS 523
Query 602 D-GPEFTFTTPK------FAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRD 645
+F F T QG+I I F L +L + F R
Sbjct 524 GYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGRC 574
Score = 65.6 bits (158), Expect = 2e-09, Method: Composition-based stats.
Identities = 44/210 (21%), Positives = 66/210 (31%), Gaps = 22/210 (10%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWS--- 270
DP PP + + L L W+ PS L Y++ + T
Sbjct 321 DPPSMACTRPPSAPRNVAFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTTQCED 380
Query 271 -----QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD-WSEEASGITYED 324
+ P T +S V D Y F I M + S + T D
Sbjct 381 CGGGLRFIPRHTGLINNSVVVLDFVSHVNYTFEIEAMNGVSELSISPKPFTAITVTTDHD 440
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA 384
PS + ++ L W+ P +NG ILDYE+ + Y+
Sbjct 441 APS-----LIGMMRKDWASQNSLALSWQA--PAFSNGAILDYEIKYYEKEHEQLTYSSTR 493
Query 385 TK-----LTVNLTNDRYLATLTVRNLVGKS 409
+K +T Y+ + VR G S
Sbjct 494 SKAPSVIVTGLKPATTYIFHIRVRTATGYS 523
>sp|Q6DFV6|FN3C1_MOUSE Fibronectin type III domain containing
protein 3C1 OS=Mus musculus OX=10090 GN=Fndc3c1 PE=2 SV=1
Length=1356
Score = 131 bits (329), Expect = 1e-29, Method: Composition-based stats.
Identities = 82/570 (14%), Positives = 153/570 (27%), Gaps = 103/570 (18%)
Query 141 KMRCEW----DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV 196
+ EW + L + L+ E A +CT+ + +
Sbjct 661 SLSLEWCAPTNPNPNDTLT--YVLEMEEAKSGLGFKPKYNGEDLTCTIR-NLQRNTMYKF 717
Query 197 WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-IL 255
+ A N G+ +P P+ V+ + + + + W P + I
Sbjct 718 RIFAYNLEGRSNPSGEVKYTTRPARPGCPNKPYVVGT-IHAHQVTIGWDLPKDNGGMNIS 776
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW-- 313
Y+++ S + + TR F DL+ T Y R+ C G+ SD
Sbjct 777 SYSLEVCENSDSA--NLWKIIYSGTRQEFLYDDLQAATTYKLRVFCTSPAGQSRPSDVLT 834
Query 314 ------------SEEASGITYED------------------------------------- 324
S+ G T
Sbjct 835 IQTPTLPPESCRSQPLRGKTKSKDANLPDNRSVNGKPEAHVRGKKAKGPHQDRKVHPSSE 894
Query 325 --------------RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
P++ P +G V + W+ A +I+DY +
Sbjct 895 KKCALGSQSMECGSVPARHPPSQCGTPVLTCKGPTCVIVSWEIPKCNGA--EIIDYRLQW 952
Query 371 TRWKSHLQNY---TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
+ + + ++ + Y + N+VG V
Sbjct 953 GQVEDSMHLIYTGPCLRYEVKGLVPATTYFCRVQAVNIVGVGMFGGTAKVTTPGTVPAMV 1012
Query 428 MDLKAFPK-------DNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
LK + + W P + Y +E+ D +
Sbjct 1013 PVLKEVESKVPAKLSSTCIAIRWEEPDCHGSPITGYNIEY----------GDKKVVTVKR 1062
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVL 537
Y+ +L + Y I + + G + P + P + G L
Sbjct 1063 ITEYVLKDLQPNTTYRIRIQAINHYGLSPFSPSIRCKTKPLPPEPPQLNCVVYGHQSLRL 1122
Query 538 EWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
+W + NY + G +V + + L+ T Y ++ A +
Sbjct 1123 KWGTVSSKKTLANFINYNVLMEDRSGR-FSVIYRGPDVTHKVQKLSEYTEYKFKIQACNE 1181
Query 598 EG-GKDGPEFTFTTPKFAQGEIEAIVVPVC 626
G G + +TFTT K ++A V
Sbjct 1182 AGEGPESDIYTFTTTKSPPTALKAPKVHPL 1211
Score = 114 bits (284), Expect = 3e-24, Method: Composition-based stats.
Identities = 58/389 (15%), Positives = 117/389 (30%), Gaps = 35/389 (9%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP---PEDTASTRSSFTVQDLKPFT 293
+ + ++W P I+ Y +Q W Q+ + V+ L P T
Sbjct 928 PTCVIVSWEIPKCNGAEIIDYRLQ--------WGQVEDSMHLIYTGPCLRYEVKGLVPAT 979
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF-WYKIDPSHTQGYRTVQLVWK 352
Y R++ + G G + A T P+ P + + + W+
Sbjct 980 TYFCRVQAVNIVGVGMFG---GTAKVTTPGTVPAMVPVLKEVESKVPAKLSSTCIAIRWE 1036
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD-A 411
P I Y + K + + L N Y + N G S +
Sbjct 1037 E--PDCHGSPITGYNIEYGD-KKVVTVKRITEYVLKDLQPNTTYRIRIQAINHYGLSPFS 1093
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
+ P ++ + ++ T + + + VL +
Sbjct 1094 PSIRCKTKPLPPEPPQLNCVVYGHQSLRLKWGTVSSKKTLANFINYNVLMEDRSGRFSVI 1153
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKV 530
V + L+E Y + G G I + ++PP+ + +
Sbjct 1154 YRGPDVTHKVQK--LSEYTEYKFKIQACNEAGEGPESDIYTFTTTKSPPTALKAPKVHPL 1211
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMV 590
N ++W+ L + + Y + G + +T ++ S+ +++ Y
Sbjct 1212 NNNSCEIKWESLEPIKGDPIV--Y--CLQVTTGKKANQIYKGPNTSFSFSNYHANSRYRF 1267
Query 591 RMAA----YTDEG-----GKDGPEFTFTT 610
++ A T G G P F+T
Sbjct 1268 KVCAGRRYETSNGLQELWGPYSPSALFST 1296
Score = 109 bits (272), Expect = 7e-23, Method: Composition-based stats.
Identities = 65/398 (16%), Positives = 119/398 (30%), Gaps = 31/398 (8%)
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
S + ++WT S + I ++ + + + DL+P
Sbjct 461 SNIQTRSATVSWTRKSNEKYDINSSMTHELALSSNGKNGTYKNIYTGNGVTVVLHDLQPC 520
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
Y R+ ++ SE S T P + ++ ++ L WK
Sbjct 521 MVYFLRVTTIRNAEHRS---VSEVVSFTTPGCEPDPPLAPTLI-----SRTKNSLSLQWK 572
Query 353 TLPPFEANG-KILDYEVTLTRWKSHLQNYTVNA----TKLTVNLTNDRYLATLTVRNLVG 407
NG KI + + K + KL + +Y L +N G
Sbjct 573 A---SNDNGSKISSFLLEWDEGKGEDFKSCYSGRLKQHKLFKLNPSTKYSFRLAAKNDFG 629
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEW----TTPRESVKKYILEWCVLSD 462
S+ + + + + K L +EW Y+LE
Sbjct 630 CSNFSETAVFYTSGKTPPAPLPPKLKEAGIYSLSLEWCAPTNPNPNDTLTYVLEMEEAKS 689
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-SIKAYLKQAPPSK 521
+ ED T NL + Y + +G +P +K + A P
Sbjct 690 GLGFKPKYNGEDLTCT----IRNLQRNTMYKFRIFAYNLEGRSNPSGEVKYTTRPARPGC 745
Query 522 GPTVRTK-KVGKNEAVLEWDQLPVDVQNGFIRNYT--IFYRTIIGNETAVNVDSSHTEYT 578
+ ++ + WD LP D I +Y+ + + N + + E+
Sbjct 746 PNKPYVVGTIHAHQVTIGWD-LPKDNGGMNISSYSLEVCENSDSANLWKIIYSGTRQEFL 804
Query 579 LSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQ 615
L + T Y +R+ + G + T TP
Sbjct 805 YDDLQAATTYKLRVFCTSPAGQSRPSDVLTIQTPTLPP 842
Score = 99.5 bits (246), Expect = 8e-20, Method: Composition-based stats.
Identities = 57/339 (17%), Positives = 106/339 (31%), Gaps = 32/339 (9%)
Query 192 VNIEVWVEAENALGKVTSDHI-NFDPVYKVKPNPPHNLSV---INSEELSSILKLTWTNP 247
V+A N +G V P V + ++ S+ + + W P
Sbjct 979 TTYFCRVQAVNIVGVGMFGGTAKVTTPGTVPAMVPVLKEVESKVPAKLSSTCIAIRWEEP 1038
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
I YNI+Y K T +I + + ++DL+P T Y RI+ + G
Sbjct 1039 DCHGSPITGYNIEYGDKKVVTVKRI---------TEYVLKDLQPNTTYRIRIQAINHYGL 1089
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
S +S T P +++ G+++++L W T+ + ++Y
Sbjct 1090 ---SPFSPSIRCKTKPLPPEPP-----QLN-CVVYGHQSLRLKWGTVSSKKTLANFINYN 1140
Query 368 VTLTRWKSHLQNY---TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
V + K+ Y + N G+ + +
Sbjct 1141 VLMEDRSGRFSVIYRGPDVTHKVQKLSEYTEYKFKIQACNEAGEGPESDIYTFTTTKSPP 1200
Query 425 HPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
+ K P +N ++W + E +K + +C+ + T ++
Sbjct 1201 TALKAPKVHPLNNNSCEIKWES-LEPIKGDPIVYCLQVTTGKKANQIYKGPNT---SFSF 1256
Query 484 GNLAESKCYLITVTP--VYADGPGSPESIKAYLKQAPPS 520
N + Y V Y G E Y A S
Sbjct 1257 SNYHANSRYRFKVCAGRRYETSNGLQELWGPYSPSALFS 1295
Score = 89.5 bits (220), Expect = 8e-17, Method: Composition-based stats.
Identities = 66/352 (19%), Positives = 114/352 (32%), Gaps = 39/352 (11%)
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
D + V NA + S+ ++F +P+PP ++I+ + S L L W
Sbjct 516 DLQPCMVYFLRVT-TIRNAEHRSVSEVVSF-TTPGCEPDPPLAPTLISRTKNS--LSLQW 571
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT----ASTRSSFTVQDLKPFTEYVFRIR 300
+ I + ++ W + ED + + L P T+Y FR+
Sbjct 572 KASNDNGSKISSFLLE--------WDEGKGEDFKSCYSGRLKQHKLFKLNPSTKYSFRLA 623
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
+ G S++SE A T S G ++ L W N
Sbjct 624 AKNDFGC---SNFSETAVFYT-----SGKTPPAPLPPKLKEAGIYSLSLEWCAPTNPNPN 675
Query 361 GKILDYEVTLTRWKSHLQNYT----VNATKLTVNL-TNDRYLATLTVRNLVGKSDAAVLT 415
L Y + + KS L + T NL N Y + NL G+S+ +
Sbjct 676 -DTLTYVLEMEEAKSGLGFKPKYNGEDLTCTIRNLQRNTMYKFRIFAYNLEGRSNPSGEV 734
Query 416 IPACDFQATHPVMD--LKAFPKDNMLWVEWTTPRES----VKKYILEWCVLSDKAPCITD 469
+ + + + W P+++ + Y LE C SD A
Sbjct 735 KYTTRPARPGCPNKPYVVGTIHAHQVTIGWDLPKDNGGMNISSYSLEVCENSDSA---NL 791
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
W+ + +L +L + Y + V G P + P +
Sbjct 792 WKIIYSGTRQEFLYDDLQAATTYKLRVFCTSPAGQSRPSDVLTIQTPTLPPE 843
Score = 84.1 bits (206), Expect = 4e-15, Method: Composition-based stats.
Identities = 75/410 (18%), Positives = 120/410 (29%), Gaps = 59/410 (14%)
Query 19 ESTGELLDPCGYISPESPVVQLHSNFTAV----CVLKEKCMDYFHVN-ANYIVWKTNHFT 73
+ G CG + P Q + CV+ + N A I ++
Sbjct 897 CALGSQSMECGSVPARHPPSQCGTPVLTCKGPTCVIVS--WEIPKCNGAEIIDYRLQWGQ 954
Query 74 IPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKP---- 129
+ + I + C + + ++G T P P
Sbjct 955 VEDSMHLIYTGPCLRYEVKGLV-PATTYFCRVQAVNIVGVGMFGGTAKVTTPGTVPAMVP 1013
Query 130 --KNLSCIVNEGKKMRC---EW-----DGGRETHLETNFTLKSEWATHKFADCKAKRDTP 179
K + V C W G T + K + + K P
Sbjct 1014 VLKEVESKVPAKLSSTCIAIRWEEPDCHGSPITGYNIEYGDKKVVTVKRITEYVLKDLQP 1073
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ ++A N G K KP PP +
Sbjct 1074 N-----------TTYRIRIQAINHYGLSPFSP---SIRCKTKPLPPEPPQLNCVVYGHQS 1119
Query 240 LKLTWTNPSIKSVIILKYNIQYR--TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
L+L W ++ S L I Y +D S + T VQ L +TEY F
Sbjct 1120 LRLKW--GTVSSKKTLANFINYNVLMEDRSGRFSVIYRGPDVT---HKVQKLSEYTEYKF 1174
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPS--KAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
+I+ E G+G SD + T + P+ KAP + S + W++L
Sbjct 1175 KIQACNEAGEGPESD---IYTFTTTKSPPTALKAPKVHPLNNNSCE-------IKWESLE 1224
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT--NDRYLATLTVR 403
P + G + Y + +T K Q Y T + + N RY +
Sbjct 1225 PIK--GDPIVYCLQVTTGKKANQIYKGPNTSFSFSNYHANSRYRFKVCAG 1272
Score = 68.0 bits (164), Expect = 4e-10, Method: Composition-based stats.
Identities = 62/421 (15%), Positives = 121/421 (29%), Gaps = 35/421 (8%)
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNL---SVINSEELSSILKLTWTNPSIKSVIILKY 257
E+ + SD P PP +L +V + ++ + S L
Sbjct 240 EHKINSTFSDTTLLLNKDIDMPAPPDSLCPYTVDTAPGTNT-------DNSTSDTYSLNT 292
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG----YWSDW 313
+ T D++ + ++ T ++ T+ + + I +D
Sbjct 293 VLNTCTIDSAPRNM--ADNIPDTNTTDTITS---SSAHTPSISTSNATFCSDNNNNITDS 347
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
S D K P I +Q + P N + +V
Sbjct 348 SISNYNQVTYDETHKPPDA-KSIPSCTSQSASNPSVSENAHNPSSINDGLRPSDVASISE 406
Query 374 KSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF 433
H + + + + + + + + T P C V +++
Sbjct 407 NDHEETEANMGAGDNKQILGENQKKSQSSNASLKEHNTEDRTQPGCFNIEKPVVSNIQ-- 464
Query 434 PKDNMLWVEWTTPRESVKKYILEWCVLSD----KAPCITDWQQEDGTVHRTYLRGNLAES 489
V WT R+S +KY + + + ++ T + +L
Sbjct 465 --TRSATVSWT--RKSNEKYDINSSMTHELALSSNGKNGTYKNIYTGNGVTVVLHDLQPC 520
Query 490 KCYLITVTPVYADGPGSPESIKAYLKQA-PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
Y + VT + S + ++ P KN L+W N
Sbjct 521 MVYFLRVTTIRNAEHRSVSEVVSFTTPGCEPDPPLAPTLISRTKNSLSLQW---KASNDN 577
Query 549 G-FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
G I ++ + + G + ++ L L T Y R+AA D G + E
Sbjct 578 GSKISSFLLEWDEGKGEDFKSCYSGRLKQHKLFKLNPSTKYSFRLAAKNDFGCSNFSETA 637
Query 608 F 608
Sbjct 638 V 638
Score = 57.2 bits (136), Expect = 7e-07, Method: Composition-based stats.
Identities = 36/205 (18%), Positives = 66/205 (32%), Gaps = 16/205 (8%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
LPPE P+ L+C+V + +R +W NF + + P
Sbjct 1103 LPPEPPQ-LNCVVYGHQSLRLKWGTVSSKKTLANFINYNVLMEDRSGRFSVIYRGPDVTH 1161
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS-EELSSILKL 242
+ + ++A N G+ I K +PP L ++ ++
Sbjct 1162 KVQKLSEYTEYKFKIQACNEAGEGPESDIYTFTTTK---SPPTALKAPKVHPLNNNSCEI 1218
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC- 301
W + + Y +Q T + + +SF+ + + Y F++
Sbjct 1219 KWESLEPIKGDPIVYCLQVTTGKKAN------QIYKGPNTSFSFSNYHANSRYRFKVCAG 1272
Query 302 -MKEDGKG---YWSDWSEEASGITY 322
E G W +S A TY
Sbjct 1273 RRYETSNGLQELWGPYSPSALFSTY 1297
>sp|P54758|EPHA6_RAT Ephrin type-A receptor 6 OS=Rattus norvegicus
OX=10116 GN=Epha6 PE=2 SV=2
Length=1035
Score = 130 bits (326), Expect = 2e-29, Method: Composition-based stats.
Identities = 53/239 (22%), Positives = 87/239 (36%), Gaps = 20/239 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH-----LETNFTLKSEWATHKFADCKAK---- 175
PP P+N++ +NE + EW +T + K + DC A
Sbjct 330 PPSAPRNVAFNINE-TALILEWSPPSDTGGRKDLTYSVICKKCGVDASQCEDCGAGLRFI 388
Query 176 ---RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP-NPPHNLSVI 231
+ V V VN +EA N + +++ F + + P + ++
Sbjct 389 PRPTGLINNSVVVLDFVSHVNYTFEIEAMNGVSELSISPKPFTAITVTTDQDAPSLIGMM 448
Query 232 NSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ S L L+W P+ + IL Y I+Y K+ Q+ T S S + LK
Sbjct 449 RKDWASQNSLALSWQAPAFSNGAILDYEIKYYEKEHE---QLTYSSTRSKAPSVIITGLK 505
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
P T Y+F IR G +S E +G E A + + G T+ +
Sbjct 506 PATTYIFHIRVRTATGYSGYSQKFEFETG--DETSDMAAEQGQILVIATAAVGGFTLLV 562
Score = 84.1 bits (206), Expect = 3e-15, Method: Composition-based stats.
Identities = 43/247 (17%), Positives = 75/247 (30%), Gaps = 26/247 (11%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL-----------SDKAPCITDWQ 471
++ + L +EW+ P ++ + L + V+ D +
Sbjct 330 PPSAPRNVAFNINETALILEWSPPSDTGGRKDLTYSVICKKCGVDASQCEDCGAGLRFIP 389
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTVR 526
+ G ++ + + + Y + + S I Q PS +R
Sbjct 390 RPTGLINNSVVVLDFVSHVNYTFEIEAMNGVSELSISPKPFTAITVTTDQDAPSLIGMMR 449
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
+N L W NG I +Y I +Y T + S ++ L
Sbjct 450 KDWASQNSLALSWQA--PAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPA 507
Query 586 TLYMVRMAAYTDEGGKD-GPEFTFTTPK------FAQGEIEAIVVPVCLAFLLTTLLGVL 638
T Y+ + T G +F F T QG+I I F L +L +
Sbjct 508 TTYIFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLF 567
Query 639 FCFNKRD 645
F R
Sbjct 568 FLITGRC 574
Score = 64.9 bits (156), Expect = 3e-09, Method: Composition-based stats.
Identities = 43/210 (20%), Positives = 66/210 (31%), Gaps = 22/210 (10%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWS--- 270
DP PP + + L L W+ PS L Y++ +
Sbjct 321 DPPSMACTRPPSAPRNVAFNINETALILEWSPPSDTGGRKDLTYSVICKKCGVDASQCED 380
Query 271 -----QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD-WSEEASGITYED 324
+ P T +S V D Y F I M + S + T +D
Sbjct 381 CGAGLRFIPRPTGLINNSVVVLDFVSHVNYTFEIEAMNGVSELSISPKPFTAITVTTDQD 440
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA 384
PS + ++ L W+ P +NG ILDYE+ + Y+
Sbjct 441 APS-----LIGMMRKDWASQNSLALSWQA--PAFSNGAILDYEIKYYEKEHEQLTYSSTR 493
Query 385 TK-----LTVNLTNDRYLATLTVRNLVGKS 409
+K +T Y+ + VR G S
Sbjct 494 SKAPSVIITGLKPATTYIFHIRVRTATGYS 523
>sp|Q9W6V5|PTPRJ_CHICK Receptor-type tyrosine-protein phosphatase
eta OS=Gallus gallus OX=9031 GN=PTPRJ PE=2 SV=2
Length=1406
Score = 130 bits (327), Expect = 2e-29, Method: Composition-based stats.
Identities = 105/574 (18%), Positives = 182/574 (32%), Gaps = 72/574 (13%)
Query 56 DYFHVNANYIVWKTNH-------FTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTF 108
+Y V + + W N + I + I+ SSVT +I L + + +F
Sbjct 178 EYVGVTSVNLTWTVNDTASASYTYRIEVTSDSSIDSLTSSVTMAEITGL---IPGTLYSF 234
Query 109 GQLEQ------NVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKS 162
G +I P +L + W T +T
Sbjct 235 KVFAVAADNRTEADGASISLYTKPSPVLDLKAEYVGVTSVNLTWT--VNGTALTAYT--Y 290
Query 163 EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 222
+ + + + + V A + ++ + KP
Sbjct 291 RIEVRNATSIRNETSNINKIEITG-LIPGTSYNFKVFATPVNNTTEEEGLSLNLY--TKP 347
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
+P L V+ + + LTW + Y I+ R + + S +
Sbjct 348 SP--VLRVVTEYVGVTSVNLTWMV-DDTASDSYTYRIEVRNGSS-------INNKTSDIT 397
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
+ L P T Y F + + DG+ E + I+ +PS +
Sbjct 398 DAEITGLIPGTLYTFTVFAVAADGQTA-----GEGASISLYTKPSPVLDLK-----AEYV 447
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQNYTVNATKLTVNLTNDRYLATL- 400
G +V L W A+ Y + +T S V ++T + Y T+
Sbjct 448 GVTSVNLTWTVNDTASAS---YTYRIEVTSDSSIDSLTSNVTMAEITGLIPGTLYNFTVF 504
Query 401 -TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
+ ++D A ++ PV DLKA + + W + Y V
Sbjct 505 AVAADNRTEADGAFTSLYT----KPTPVTDLKAEHGVTSVSLNWMVNDTASDSYTYRIEV 560
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP--GSPESIKAYLKQA 517
+ + + T + G L Y TV V ADG G SI Y K
Sbjct 561 RNGH-----SVNNKTSNIPETEITG-LNPGTLYTFTVFAVAADGETEGEGASISVYTK-- 612
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH-TE 576
P ++T+ VG L W D +YT YR + N +++N +S T+
Sbjct 613 -PRAVLHLKTEYVGVTSVNLTWTVNDTDSA-----SYT--YRIEVRNGSSINNKTSDITD 664
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
++ L TLY+ + A +G G + +
Sbjct 665 AEITGLDPGTLYIFTVFAVAADGQTAGEGASISL 698
Score = 118 bits (294), Expect = 1e-25, Method: Composition-based stats.
Identities = 103/570 (18%), Positives = 174/570 (31%), Gaps = 64/570 (11%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTC----NILTFGQL 111
+Y V + + W N Y I R SS+ + ++T + TF
Sbjct 89 EYVGVTSVNLTWTVNDTASDSYTYRIEVRNGSSINNKTSDITDAEITGLIPGTLYTFTVF 148
Query 112 EQNVYGITIISGLP------PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA 165
G T G P +L + W ++T + E
Sbjct 149 AVAADGQTAGEGASISLYTKPSPVLDLKAEYVGVTSVNLTWT--VNDTASASYTYRIEVT 206
Query 166 THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPP 225
+ D T T + V A+N + +D + KP+P
Sbjct 207 SDSSIDSLTSSVTMAEITGLIPGTLYSFKVFAVAADN---RTEADGASISLY--TKPSPV 261
Query 226 HNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
+L S + LTWT Y I+ R + + S +
Sbjct 262 LDLKAEYVGVTS--VNLTWTVNGTALTAYT-YRIEVRNATS-------IRNETSNINKIE 311
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
+ L P T Y F++ + EE + +PS + G
Sbjct 312 ITGLIPGTSYNFKVFATPVNNTTE-----EEGLSLNLYTKPSPVLRV-----VTEYVGVT 361
Query 346 TVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQNYTVNATKLTVNLTNDRYLATLTVRN 404
+V L W + Y + + S + + + ++T + Y T+
Sbjct 362 SVNLTWMVDDTASDS---YTYRIEVRNGSSINNKTSDITDAEITGLIPGTLYTFTVFAVA 418
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKA-FPKDNMLWVEWTTPRESVKKYILEWCVLSDK 463
G++ +I + PV+DLKA + + + WT + Y V SD
Sbjct 419 ADGQTAGEGASISL--YTKPSPVLDLKAEYVGVTSVNLTWTVNDTASASYTYRIEVTSDS 476
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA--YLKQAPPSK 521
V + G L Y TV V AD + Y K P+
Sbjct 477 -----SIDSLTSNVTMAEITG-LIPGTLYNFTVFAVAADNRTEADGAFTSLYTK---PTP 527
Query 522 GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT-LS 580
++ + G L W +YT YR + N +VN +S+ T ++
Sbjct 528 VTDLKAEH-GVTSVSLNWMVNDTASD-----SYT--YRIEVRNGHSVNNKTSNIPETEIT 579
Query 581 SLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
L TLY + A +G +G + +
Sbjct 580 GLNPGTLYTFTVFAVAADGETEGEGASISV 609
Score = 103 bits (257), Expect = 4e-21, Method: Composition-based stats.
Identities = 81/411 (20%), Positives = 145/411 (35%), Gaps = 51/411 (12%)
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK 264
G+ SD + +P +L S + LTWT + + Y I+ R
Sbjct 68 GRAMSDQNSV-----AQPRAVLDLKTEYVGVTS--VNLTWTV-NDTASDSYTYRIEVRNG 119
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
+ + S + + L P T Y F + + DG+ E + I+
Sbjct 120 SS-------INNKTSDITDAEITGLIPGTLYTFTVFAVAADGQTA-----GEGASISLYT 167
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQNYTVN 383
+PS + G +V L W A+ Y + +T S +V
Sbjct 168 KPSPVLDLK-----AEYVGVTSVNLTWTVNDTASAS---YTYRIEVTSDSSIDSLTSSVT 219
Query 384 ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA-FPKDNMLWVE 442
++T + Y + +++A +I + PV+DLKA + + +
Sbjct 220 MAEITGLIPGTLYSFKVFAVAADNRTEADGASISL--YTKPSPVLDLKAEYVGVTSVNLT 277
Query 443 WTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV--TPVY 500
WT ++ Y + + + T + E +++ + G L Y V TPV
Sbjct 278 WTVNGTALTAY--TYRI---EVRNATSIRNETSNINKIEITG-LIPGTSYNFKVFATPVN 331
Query 501 ADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
S+ Y K +P + V T+ VG L W +YT YR
Sbjct 332 NTTEEEGLSLNLYTKPSPVLR---VVTEYVGVTSVNLTWMVDDTASD-----SYT--YRI 381
Query 561 IIGNETAVNVDSSH-TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ N +++N +S T+ ++ L TLY + A +G G + +
Sbjct 382 EVRNGSSINNKTSDITDAEITGLIPGTLYTFTVFAVAADGQTAGEGASISL 432
Score = 95.7 bits (236), Expect = 1e-18, Method: Composition-based stats.
Identities = 85/562 (15%), Positives = 155/562 (28%), Gaps = 62/562 (11%)
Query 54 CMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTC----NILTFG 109
+Y V + + W + Y I R SS+ + ++T + TF
Sbjct 354 VTEYVGVTSVNLTWMVDDTASDSYTYRIEVRNGSSINNKTSDITDAEITGLIPGTLYTFT 413
Query 110 QLEQNVYGITIISGLP------PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSE 163
G T G P +L + W ++T + E
Sbjct 414 VFAVAADGQTAGEGASISLYTKPSPVLDLKAEYVGVTSVNLTWT--VNDTASASYTYRIE 471
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN 223
+ D T T + V A A + +D KP
Sbjct 472 VTSDSSIDSLTSNVTMAEITG---LIPGTLYNFTVFAVAADNRTEADGAFTSLY--TKPT 526
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P +L E + + L W + + Y I+ R + + S
Sbjct 527 PVTDLKA---EHGVTSVSLNWMV-NDTASDSYTYRIEVR-------NGHSVNNKTSNIPE 575
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+ L P T Y F + + DG+ S P + + G
Sbjct 576 TEITGLNPGTLYTFTVFAVAADGETEGEGASISVYTK---------PRAVLHLK-TEYVG 625
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQNYTVNATKLTVNLTNDRYLATLTV 402
+V L W A+ Y + + S + + + ++T Y+ T+
Sbjct 626 VTSVNLTWTVNDTDSAS---YTYRIEVRNGSSINNKTSDITDAEITGLDPGTLYIFTVFA 682
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKA-FPKDNMLWVEWTTPRESVKKYILEWCVLS 461
G++ +I + V++LKA + + + W Y V
Sbjct 683 VAADGQTAGEGASISLYTKPSM--VLNLKAEYVTMTSVNLTWMVNDAESASYTYRIEVAH 740
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA----DGPGSPESIKAYLKQA 517
+ E + + L Y TV + A +G G+ S
Sbjct 741 ESL------INETMSNVTKSIVTYLIPGTSYNFTVFAIAADNQTEGEGASISQN-----T 789
Query 518 PPSKGPTVRTKKVGKNE-AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
PS + + V L+W+ I + + ++ + S
Sbjct 790 VPSSVNAFQCEAVANMSYLTLKWNCPYGGYSGFDIEIFNGTWTKKQQSQFCGR-EGSEEI 848
Query 577 YTLSSLTSDTLYMVRMAAYTDE 598
+ L Y V + +D
Sbjct 849 FKTEPLDYYKTYTVSVTTVSDG 870
>sp|O89026|ROBO1_MOUSE Roundabout homolog 1 OS=Mus musculus OX=10090
GN=Robo1 PE=1 SV=1
Length=1612
Score = 129 bits (325), Expect = 3e-29, Method: Composition-based stats.
Identities = 107/642 (17%), Positives = 196/642 (31%), Gaps = 107/642 (17%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P + V + + C + + W+ + +PK +Y I + +
Sbjct 229 PSNLAVTVDDSAEFKC-------EARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKV 281
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLPPE---KPKNLSCIVNEGKKMRCE---- 145
+ G+ E + T+ PP KP++ + +CE
Sbjct 282 TAGDMGSYTCVAENMVGKAEAS---ATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGN 338
Query 146 ------WDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
W RE F+ + ++ +F+ + T T+ Y++ +
Sbjct 339 PQPAIFWR--REGSQNLLFSYQPPQSSSRFSVSQTGDLTITN-VQRSDVGYYICQTL--- 392
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
N G + + + PP + + ++ +IL
Sbjct 393 --NVAGSI-ITKAYLEVTDVIADRPPPVIRQGPVNQTVAV----------DGTLILSCVA 439
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR-------------CMKEDG 306
W + + + ++ L+ V +IR G
Sbjct 440 TGSPAPTILWRK---DGVLVSTQDSRIKQLESG---VLQIRYAKLGDTGRYTCTASTPSG 493
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS----HTQGYRTVQLVWKTL--PPFEAN 360
+ WS + E P PS TV L W+
Sbjct 494 EATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLSWQPNLNSGATPT 553
Query 361 GKILD--YEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT--I 416
I++ + + W++ +N + N YL + N G SD + ++ +
Sbjct 554 SYIIEAFSHASGSSWQTAAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPV 613
Query 417 PACDFQATHPVMDLKAFP----------------KDNMLWVEWTTPRESVKKYILEWCVL 460
D T +D K + + V WT ++S +YI + +L
Sbjct 614 KTQDVPPTSQGVDHKQVQRELGNVVLHLHNPTILSSSSVEVHWTVDQQS--QYIQGYKIL 671
Query 461 SDKAP---CITDW---QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK-AY 513
+ ++W + T + + L + Y I P + + G+ IK A
Sbjct 672 YRPSGASHGESEWLVFEVRTPTKNSVVIPD-LRKGVNYEIKARPFFNEFQGADSEIKFAK 730
Query 514 LKQAPPSKGP---TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA--- 567
+ PS P TV ++ W P D QNG ++ Y ++ +GNET
Sbjct 731 TLEEAPSAPPRSVTVSKNDGNGTAILVTWQPPPEDTQNGMVQEYKVW---CLGNETKYHI 787
Query 568 -VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
VD S + SL Y V +AA T G E F
Sbjct 788 NKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGPGVKSEPQF 829
Score = 122 bits (305), Expect = 9e-27, Method: Composition-based stats.
Identities = 80/533 (15%), Positives = 146/533 (27%), Gaps = 82/533 (15%)
Query 30 YISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNH-------FTIPKEQYTII 82
+ P VV L T C + I W+ + P+
Sbjct 315 VVKPRDQVVALGRTVTFQC-------EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFS 367
Query 83 NRTASSVTFTDIASLNIQL----TCNILTFGQLEQNVYGITIISGLPP----EKPKN--- 131
+T T++ ++ T N+ + + +I+ PP + P N
Sbjct 368 VSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTV 427
Query 132 -------LSCIVNEGKKMRCEW--DGGRETHLETNF--TLKSEWATHKFADCKAKRDTPT 180
LSC+ W DG + ++ R T T
Sbjct 428 AVDGTLILSCVATGSPAPTILWRKDGVLVSTQDSRIKQLESGVLQIRYAKLGDTGRYTCT 487
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
+ T + IEV G DP P+ P V + + +
Sbjct 488 ASTPSGEATWSAYIEVQ-----EFGVPVQPPRPTDPNLI--PSAPSKPEVTDV--SKNTV 538
Query 241 KLTWTNPSIKSVIILKYNIQ-YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
L+W Y I+ + S+W +F ++ LKP Y+F +
Sbjct 539 TLSWQPNLNSGATPTSYIIEAFSHASGSSWQTAAEN---VKTETFAIKGLKPNAIYLFLV 595
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS------------HTQGYRTV 347
R G SD S+ + + +D P + +K +V
Sbjct 596 RAANAYGI---SDPSQISDPVKTQDVPPTSQGVDHKQVQRELGNVVLHLHNPTILSSSSV 652
Query 348 QLVWKTLPPFEANGKILDYEVTLTR-WKSHLQNY-------TVNATKLTVNLTNDRYLAT 399
++ W + + I Y++ SH ++ T + +
Sbjct 653 EVHWTV---DQQSQYIQGYKILYRPSGASHGESEWLVFEVRTPTKNSVVIPDLRKGVNYE 709
Query 400 LTVRNLVGKSDAAVLTI---PACDFQATHPVMDLKAF---PKDNMLWVEWTTPRESVKKY 453
+ R + A I + + P + + V W P E +
Sbjct 710 IKARPFFNEFQGADSEIKFAKTLEEAPSAPPRSVTVSKNDGNGTAILVTWQPPPEDTQNG 769
Query 454 -ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
+ E+ V + + + +L Y + V GPG
Sbjct 770 MVQEYKVWCLGNETKYHINKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGPG 822
>sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 OS=Homo sapiens
OX=9606 GN=EPHA5 PE=1 SV=3
Length=1037
Score = 129 bits (323), Expect = 4e-29, Method: Composition-based stats.
Identities = 56/250 (22%), Positives = 94/250 (38%), Gaps = 28/250 (11%)
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDK---- 463
+SD + AC + P + + +++EW P ++ + + + + K
Sbjct 346 ESDPPTM---ACTRPPSAPRNAISNV-NETSVFLEWIPPADTGGRKDVSYYIACKKCNSH 401
Query 464 ----APCITDWQ---QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-----ESIK 511
C + ++ G + + + +L Y + V SP S+
Sbjct 402 AGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVN 461
Query 512 AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD 571
QA PS V+ K+ KN L W + D NG I Y I Y + +
Sbjct 462 VTTNQAAPSPVTNVKKGKIAKNSISLSWQE--PDRPNGIILEYEIKYFEKDQETSYTIIK 519
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTF-TTPKFA----QGEIEAIVVPV 625
S T T L ++Y+ ++ A T G G F F TTP FA Q +I I V V
Sbjct 520 SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSV 579
Query 626 CLAFLLTTLL 635
+ +L ++
Sbjct 580 TVGVILLAVV 589
Score = 118 bits (295), Expect = 9e-26, Method: Composition-based stats.
Identities = 43/214 (20%), Positives = 77/214 (36%), Gaps = 19/214 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHK---FADCKA----- 174
PP P+N VNE + EW +T + ++ + + +C
Sbjct 357 PPSAPRNAISNVNE-TSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYL 415
Query 175 --KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHI-NFDPVYKVKPNPPHNLS-V 230
+ + + + N +EA N + ++ P ++ V
Sbjct 416 PRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNV 475
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + + L+W P + IIL+Y I+Y KD T S ++ T + LK
Sbjct 476 KKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQET----SYTIIKSKETTITAEGLK 531
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
P + YVF+IR G G +S E + +
Sbjct 532 PASVYVFQIRARTAAGYGVFSRRFEFETTPVFAA 565
Score = 71.0 bits (172), Expect = 4e-11, Method: Composition-based stats.
Identities = 42/245 (17%), Positives = 70/245 (29%), Gaps = 38/245 (16%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDA------- 266
DP PP S + + L W P+ + Y I + ++
Sbjct 348 DPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEE 407
Query 267 -STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE------EASG 319
+ P + +S + DL T Y F I + SD S +
Sbjct 408 CGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGV-----SDLSPGARQYVSVNV 462
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN 379
T + PS + ++ L W+ P NG IL+YE+
Sbjct 463 TTNQAAPSPVTNVK-----KGKIAKNSISLSWQE--PDRPNGIILEYEIKYFEKDQETSY 515
Query 380 YTVNA--TKLTVNLTNDR--YLATLTVRNLVGKSD-------AAVLTIPACDFQATHPVM 428
+ + T +T Y+ + R G A Q+ PV+
Sbjct 516 TIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVI 575
Query 429 DLKAF 433
+
Sbjct 576 AVSVT 580
>sp|Q9VWE0|DOME_DROME Cytokine receptor OS=Drosophila melanogaster
OX=7227 GN=dome PE=1 SV=1
Length=1282
Score = 128 bits (322), Expect = 6e-29, Method: Composition-based stats.
Identities = 131/848 (15%), Positives = 253/848 (30%), Gaps = 116/848 (14%)
Query 29 GYISPESPVVQLHSNFTAVCVLKE---KCMDYFHVNANYIVWKTNHFTIPKEQYTIINRT 85
G++ P + +F C L E + + ++ I
Sbjct 28 GWVIPSKVEQLIGGDFNLSCTLNEDYFNGKSAEDCPVEKLYFTGGGRVYRDSKHIRILNN 87
Query 86 ASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCE 145
+ + + N N E + + G P ++ +C+ + + M C
Sbjct 88 TTIL----FSDTNAVEQENDYHCMCDEYVINKSKVYVGTRPLLVRDFNCLDYDFQFMVCN 143
Query 146 WDGGRETHLETNFTLKS----EWATHKFADCKAKRDTPTSC--TVDYSTVYFVNIEVWVE 199
+ T + T + + +W DC +C T D + +
Sbjct 144 FTQPPNTVI-TKYNISYNTNNDWRYSNTLDCNFDSAPVVTCNLTDDNYKRFSETFYFRLS 202
Query 200 AENALGKVTSDHINFDPVYKVKPNPP-HNLSVINSEELSSILKLTWTNPSIKSVII-LKY 257
NALG T I + ++ P P NL+++N E S + L+W P + L +
Sbjct 203 ISNALGHET-QPITINHFERLVPARPGQNLTLLNRTE--SSVCLSWEMPRRSNYNRGLVW 259
Query 258 NIQ-----YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT--EYVFRIRCMKEDGKGYW 310
++ + +W T + + + + +L PF Y R+R W
Sbjct 260 QVRVTPQNFEPITRPSWRN----HTLTIKDTLCLTEL-PFAGYNYTLRVRVRANQNNTLW 314
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S+ P + P + ++ W+ L E NG Y ++
Sbjct 315 SEPM--IYAFATAPAPPRRPPRVTYGSFYVYSSEKAMRFYWEPLEEHELNGPDFRYSISE 372
Query 371 TRWKSHLQN----YTVNATKLTVNLTNDR-YLATLTVRNLVGKS----DAAVLTIPACDF 421
R + + + + + + + + N G S + I DF
Sbjct 373 YRINGTAVDPGLIKVESNSAMIDHWSMSAVHHFLIRSSNSQGLSVNATPMTIGPISNRDF 432
Query 422 QATHPVMDLKAF-PKDNMLWVEWTTPRE--SVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
+ P + P + + W P + ++ Y + WCV + V
Sbjct 433 KVREPRNIRSVYHPTNKSYTLSWDPPSDQRELQNYTVFWCVPKPGLQSECEGSIRFAEVA 492
Query 479 RTYLRGNLAESKC--YLITVTP-VYADGPG-----SPESIKAYLKQAPPSKGPTVRTKKV 530
+ + + V+ + G K L + PS
Sbjct 493 SGLHHFTTSPDQLLTLHMAVSANYQSHNTGLHWAICSSDKKDDLAKMEPS------IDVA 546
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFY--RTIIGNE--TAVNVDSSHTEYTLSSLTSDT 586
+ W + V + Y + Y R+ + T V +D ++ + +L T
Sbjct 547 TSTSLTVSWSE---RVCAVILAGYNLTYCQRSAGRPDNCTTVTIDRYTNKHVIQNLVPYT 603
Query 587 LYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDL 646
Y V+M Y+ D ++ + A P L + T V K L
Sbjct 604 DYSVKMLMYS-----DSRVSKYSDELVNRTGEAAPSQPRELQLIRVTSDSVELA-WKPPL 657
Query 647 IK-----------KHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVE 695
+ + + NV D + + N K Y GN T + E
Sbjct 658 LANGVVRAYEGTFRSLHDNVTDTFRVSAS------ADELVNNEKPITYRLGNLTAFTKYE 711
Query 696 IEANDKKPFPEDLKSLDLFKKE-KINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTS 754
I + +P + ++ LF + + I + P SS + E + +
Sbjct 712 ISVRARTVYPSEPSNVILFSTAIGVPSPPQLYVI--------NNPDQSSRLDWEPPRTPA 763
Query 755 STVQYSTV------VHSGYRHQVPS-----VQVFSRSESTQPL------LDSEERPEDLQ 797
+ + + +P V R S P ++ E+ P+ L
Sbjct 764 GRIDFYEISLRDNNASCLTSTILPGRNLSYVMATPRCTSHNPFQLAVRAINVEQHPQ-LN 822
Query 798 LVDHVDGG 805
D +G
Sbjct 823 GADAAEGA 830
>sp|Q80X19|COEA1_MOUSE Collagen alpha-1(XIV) chain OS=Mus musculus
OX=10090 GN=Col14a1 PE=1 SV=2
Length=1797
Score = 128 bits (321), Expect = 1e-28, Method: Composition-based stats.
Identities = 78/506 (15%), Positives = 139/506 (27%), Gaps = 73/506 (14%)
Query 127 EKPKNLSCIVNEGKKMRCEW--DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P L + W G+ + + T + D S TV
Sbjct 355 GPPTELITSEVTARSFMVNWTQSPGKVEKYRVVY-----YPTRGGKPEEVVVDGSVSSTV 409
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ + ++ V A +A S+ + P +L + + E S +++ W
Sbjct 410 LKNLMSSTEYQIAVFAVSA--HTASEGLRGAETTLALPMA-SDLELYDVTENS--MRVRW 464
Query 245 TN-PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
P Y I Y T + + L P TEY + M
Sbjct 465 DAVPGA-----TGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLFPNTEYTVTVYAM- 518
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
+ + S+ A+G P P + G + +L W A+GKI
Sbjct 519 -----FGEEASDPATGQ-ETTLPLTPPRNLRISNV----GSNSARLTWDP-----ASGKI 563
Query 364 LDYEVTLTRWKSH----LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
Y + T ++ + L Y + G+S V
Sbjct 564 SGYRIVYTSADGTEINEVEVDPITTFPLKGLTPLTEYSIAIFSIYEEGQSLPLVGEFTTE 623
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ A + K + V W ++ L W + D ++E
Sbjct 624 EVPAQQYLEI--DEVKTDSFRVTWHPLSAEEGQHKLMWIPVYGGKTQEVDLKEE----QD 677
Query 480 TYLRGNLAESKCYLITVTPVYADG-PGSPESIKAYL-----KQAP----PSKG------- 522
+Y+ L Y +++ V DG + +AP P+
Sbjct 678 SYVIEGLDPGTEYEVSLLAVLDDGSESEVVTAVGTTLDDFWTEAPTAIEPTSPVTSVLQT 737
Query 523 --PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA-----VNVDSSHT 575
+ + WD + + + + + Y G+ V V
Sbjct 738 GIRNLVVDDETATSLRVSWD-----ISDSNVEQFRVTYLKAQGDPMEEVVGTVMVPGVQN 792
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGK 601
L +L DT Y V + G
Sbjct 793 SLLLKALLPDTEYKVTVTPVYTVGEG 818
Score = 112 bits (279), Expect = 1e-23, Method: Composition-based stats.
Identities = 71/515 (14%), Positives = 154/515 (30%), Gaps = 64/515 (12%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDG--GRETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
LP P+NL R WD G+ + +T + + + P +
Sbjct 534 LPLTPPRNLRISNVGSNSARLTWDPASGKISGYRIVYT---SADGTEINEVEVD---PIT 587
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
+ + + G+ F P + E + +
Sbjct 588 TFPLKGLTPLTEYSIAIFSIYEEGQSLPLVGEFTTEEV-----PAQQYLEIDEVKTDSFR 642
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+TW S + ++ + + ++ D + S+ ++ L P TEY +
Sbjct 643 VTWHPLSAEEG---QHKLMWIPVYGGKTQEV---DLKEEQDSYVIEGLDPGTEYEVSLLA 696
Query 302 MKEDGKGYWSD------------WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
+ +D G S+ W+E + I + + + ++++
Sbjct 697 VLDD--GSESEVVTAVGTTLDDFWTEAPTAIEPTSPVTSVLQTGIRNLVVDDETATSLRV 754
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV---------NATKLTVNLTNDRYLATL 400
W ++N + + VT + + V N+ L L + Y T+
Sbjct 755 SWD---ISDSN--VEQFRVTYLKAQGDPMEEVVGTVMVPGVQNSLLLKALLPDTEYKVTV 809
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
T VG+ + ++ P ++ P + N + + W P VK Y + + +
Sbjct 810 TPVYTVGEGVS--VSAPGKTLPSSGPQNLRVSEEWYNRVRITWDPPSGPVKGYRIVYKPV 867
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS 520
S + + G T + NL Y + + + G +++ ++
Sbjct 868 SVPGQTL---ETFVGADINTIVMTNLLSGMDYNVKIFA--SQASGFSDALTGLVQ-TLFL 921
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT-IIGNETAVNVDSSHTEYTL 579
++ +V W Y I + V +
Sbjct 922 GVTDLQANQVEMTSLCARWQIHR------HATAYRIVLESLQDTQAQESTVGGGVNRHCF 975
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFA 614
L D+ Y + + YT +GP + +
Sbjct 976 YGLQPDSEYKISV--YTKLQELEGPSVSIMQKTQS 1008
Score = 81.8 bits (200), Expect = 2e-14, Method: Composition-based stats.
Identities = 72/452 (16%), Positives = 144/452 (32%), Gaps = 66/452 (15%)
Query 213 NFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQI 272
F + + + PP L + ++++W P Y + +Q+
Sbjct 21 CFCTIVRGQVAPPTRLR--YNVISHDSIQISWKAP---RGKFGGYKLLVAPASGGKTNQM 75
Query 273 PPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED--------------------------- 305
++TA + +Q L P Y ++ +D
Sbjct 76 NLQNTA---TKAIIQGLLPEQNYTVQLIAYYKDKESKPAQGQFRIKDLEKRKDPTKPKVK 132
Query 306 --GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
KG S + + + P+ A +D S + G +LV +
Sbjct 133 VVDKGNGSKPTSPEEVKFFCETPAIA-DIVILVDGSWSIGRFNFRLV-----RNFLENLV 186
Query 364 LDYEVTLTRWKSHLQNYTVNA---TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
+ V + + L Y+ + L T D + + G + L +
Sbjct 187 TAFNVGSEKTRIGLAQYSGDPRIEWHLNAFNTKDEVIDAVRSLPYKGGNTLTGLALNFIF 246
Query 421 FQATHPVMDLKAFPKDNMLWVE-------WTTPRESVKKYILEWCVLSDKAPCITDWQQE 473
+ P ++ + + P ++++ +E + K +++ Q+
Sbjct 247 ENSFKPEAGSRSGVSKIGILITDGKSQDDIIPPSRNLRESGVELFAIGVKNADLSELQEI 306
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS---KGPTVRTKKV 530
T++ N+AE V + E +K + + + T +V
Sbjct 307 ASEPDSTHVY-NVAEFDLMHTVVESLTRTVCSRVEEQDKEIKASALATIGPPTELITSEV 365
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLY- 588
++ W Q P G + Y + +Y T G V VD S + L +L S T Y
Sbjct 366 TARSFMVNWTQSP-----GKVEKYRVVYYPTRGGKPEEVVVDGSVSSTVLKNLMSSTEYQ 420
Query 589 --MVRMAAYTDEGGKDGPEFTFTTPKFAQGEI 618
+ ++A+T G G E T P + E+
Sbjct 421 IAVFAVSAHTASEGLRGAETTLALPMASDLEL 452
>sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 OS=Rattus norvegicus
OX=10116 GN=Epha5 PE=1 SV=1
Length=1005
Score = 127 bits (319), Expect = 1e-28, Method: Composition-based stats.
Identities = 57/251 (23%), Positives = 88/251 (35%), Gaps = 30/251 (12%)
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
+SD + AC + P + + +++EW P ++ + + +L K
Sbjct 348 ESDPPTM---ACTRPPSAPRNAISNV-NETSVFLEWIPPADTGGGKDVSYYILCKKCNSH 403
Query 468 TDW------------QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-----ESI 510
QQ + LA Y + V SP S+
Sbjct 404 AGVCEECGGHVRYLPQQIGLKNTSVMMADPLA-HTNYTFEIEAVNGVSDLSPGTRQYVSV 462
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
QA PS V+ K+ KN L W + D NG I Y I Y + +
Sbjct 463 NVTTNQAAPSPVTNVKKGKIAKNSISLSWQE--PDRPNGIILEYEIKYFEKDQETSYTII 520
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTF-TTPKFA----QGEIEAIVVP 624
S T T L ++Y+ ++ A T G G F F TTP F Q +I I V
Sbjct 521 KSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFGASNDQSQIPIIGVS 580
Query 625 VCLAFLLTTLL 635
V + +L ++
Sbjct 581 VTVGVILLAVM 591
Score = 118 bits (296), Expect = 7e-26, Method: Composition-based stats.
Identities = 44/209 (21%), Positives = 72/209 (34%), Gaps = 19/209 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH-----LETNFTLKSEWATHKFADCKA----- 174
PP P+N VNE + EW +T K +C
Sbjct 359 PPSAPRNAISNVNE-TSVFLEWIPPADTGGGKDVSYYILCKKCNSHAGVCEECGGHVRYL 417
Query 175 --KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS-DHINFDPVYKVKPNPPHNLS-V 230
+ + + + N +EA N + ++ P ++ V
Sbjct 418 PQQIGLKNTSVMMADPLAHTNYTFEIEAVNGVSDLSPGTRQYVSVNVTTNQAAPSPVTNV 477
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + + L+W P + IIL+Y I+Y KD T S ++ T + LK
Sbjct 478 KKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQET----SYTIIKSKETTITAEGLK 533
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
P + YVF+IR G G +S E +
Sbjct 534 PASVYVFQIRARTAAGYGVFSRRFEFETT 562
Score = 64.9 bits (156), Expect = 3e-09, Method: Composition-based stats.
Identities = 36/209 (17%), Positives = 63/209 (30%), Gaps = 25/209 (12%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTKDA------- 266
DP PP S + + L W P+ + Y I + ++
Sbjct 350 DPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGGKDVSYYILCKKCNSHAGVCEE 409
Query 267 -STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE---ASGITY 322
+ P+ +S + D T Y F I + G S + + + T
Sbjct 410 CGGHVRYLPQQIGLKNTSVMMADPLAHTNYTFEIEAVN--GVSDLSPGTRQYVSVNVTTN 467
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
+ PS + ++ L W+ P NG IL+YE+ +
Sbjct 468 QAAPSPVTNVK-----KGKIAKNSISLSWQE--PDRPNGIILEYEIKYFEKDQETSYTII 520
Query 383 NA--TKLTVNLTNDR--YLATLTVRNLVG 407
+ T +T Y+ + R G
Sbjct 521 KSKETTITAEGLKPASVYVFQIRARTAAG 549
>sp|P54755|EPHA5_CHICK Ephrin type-A receptor 5 OS=Gallus gallus
OX=9031 GN=EPHA5 PE=2 SV=1
Length=1013
Score = 126 bits (317), Expect = 2e-28, Method: Composition-based stats.
Identities = 54/250 (22%), Positives = 91/250 (36%), Gaps = 28/250 (11%)
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW------CVLS 461
+SD + AC + P + + +++EW P ++ + + + C
Sbjct 322 ESDPPTM---ACTRPPSAPRSAISNV-NETSVFLEWIPPADTGGRKDVSYYIACKKCNSH 377
Query 462 DK-----APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-----ESIK 511
+ Q+ G + + + +L Y + V +P S+
Sbjct 378 SGLCEACGSHVRYLPQQTGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDQNPGARQFVSVN 437
Query 512 AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD 571
QA PS +V+ K+ KN L W + D NG I Y I Y + +
Sbjct 438 VTTNQAAPSPVSSVKKGKITKNSISLSWQE--PDRPNGIILEYEIKYFEKDQETSYTIIK 495
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTT-PKFA----QGEIEAIVVPV 625
S T T L + Y+ ++ A T G G F F T P A Q +I IVV V
Sbjct 496 SKETAITADGLKPGSAYVFQIRARTAAGYGGFSRRFEFETSPVLAASSDQSQIPIIVVSV 555
Query 626 CLAFLLTTLL 635
+ +L ++
Sbjct 556 TVGVILLAVV 565
Score = 114 bits (285), Expect = 2e-24, Method: Composition-based stats.
Identities = 46/214 (21%), Positives = 76/214 (36%), Gaps = 19/214 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHKFADCKA-------- 174
PP P++ VNE + EW +T + ++ + + C+A
Sbjct 333 PPSAPRSAISNVNE-TSVFLEWIPPADTGGRKDVSYYIACKKCNSHSGLCEACGSHVRYL 391
Query 175 --KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKV--KPNPPHNLSV 230
+ + + + N +EA N + F V + P SV
Sbjct 392 PQQTGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDQNPGARQFVSVNVTTNQAAPSPVSSV 451
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + + L+W P + IIL+Y I+Y KD T S ++ T LK
Sbjct 452 KKGKITKNSISLSWQEPDRPNGIILEYEIKYFEKDQET----SYTIIKSKETAITADGLK 507
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
P + YVF+IR G G +S E +
Sbjct 508 PGSAYVFQIRARTAAGYGGFSRRFEFETSPVLAA 541
Score = 71.8 bits (174), Expect = 2e-11, Method: Composition-based stats.
Identities = 37/207 (18%), Positives = 63/207 (30%), Gaps = 21/207 (10%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDA------- 266
DP PP S + + L W P+ + Y I + ++
Sbjct 324 DPPTMACTRPPSAPRSAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHSGLCEA 383
Query 267 -STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW-SEEASGITYED 324
+ + P+ T +S + DL T Y F I + + T +
Sbjct 384 CGSHVRYLPQQTGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDQNPGARQFVSVNVTTNQA 443
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA 384
PS S ++ L W+ P NG IL+YE+ + +
Sbjct 444 APSPVSSVK-----KGKITKNSISLSWQE--PDRPNGIILEYEIKYFEKDQETSYTIIKS 496
Query 385 --TKLTVNLTN--DRYLATLTVRNLVG 407
T +T + Y+ + R G
Sbjct 497 KETAITADGLKPGSAYVFQIRARTAAG 523
>sp|Q9Y6N7|ROBO1_HUMAN Roundabout homolog 1 OS=Homo sapiens OX=9606
GN=ROBO1 PE=1 SV=1
Length=1651
Score = 127 bits (318), Expect = 2e-28, Method: Composition-based stats.
Identities = 102/642 (16%), Positives = 190/642 (30%), Gaps = 107/642 (17%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P + V + + C + + W+ + +PK +Y I + +
Sbjct 268 PSNLAVTVDDSAEFKC-------EARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKV 320
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLPPE---KPKNLSCIVNEGKKMRCE---- 145
+ G+ E + T+ PP KP++ + +CE
Sbjct 321 TAGDMGSYTCVAENMVGKAEAS---ATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGN 377
Query 146 ------WDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
W RE F+ + ++ +F+ + T T+ Y++ +
Sbjct 378 PQPAIFWR--REGSQNLLFSYQPPQSSSRFSVSQTGDLTITN-VQRSDVGYYICQTL--- 431
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
N G + + + PP + + ++ +L
Sbjct 432 --NVAGSI-ITKAYLEVTDVIADRPPPVIRQGPVNQTVAV----------DGTFVLSCVA 478
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR-------------CMKEDG 306
W + + + ++ L+ V +IR G
Sbjct 479 TGSPVPTILWRK---DGVLVSTQDSRIKQLENG---VLQIRYAKLGDTGRYTCIASTPSG 532
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS----HTQGYRTVQLVWKTL--PPFEAN 360
+ WS + E P PS TV L W+
Sbjct 533 EATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPT 592
Query 361 GKILD--YEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
I++ + + W++ +N + + N YL + N G SD + ++ P
Sbjct 593 SYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPV 652
Query 419 CDFQATHPVMDL------------------KAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
+ + + V WT ++S +YI + +L
Sbjct 653 KTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQS--QYIQGYKIL 710
Query 461 SDKAP---CITDW---QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK-AY 513
+ +DW + + + L + Y I P + + G+ IK A
Sbjct 711 YRPSGANHGESDWLVFEVRTPAKNSVVIPD-LRKGVNYEIKARPFFNEFQGADSEIKFAK 769
Query 514 LKQAPPSKGP---TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA--- 567
+ PS P TV ++ W P D QNG ++ Y ++ +GNET
Sbjct 770 TLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVW---CLGNETRYHI 826
Query 568 -VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
VD S + L Y V +AA T G E F
Sbjct 827 NKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQF 868
Score = 114 bits (284), Expect = 2e-24, Method: Composition-based stats.
Identities = 75/530 (14%), Positives = 137/530 (26%), Gaps = 76/530 (14%)
Query 30 YISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNH-------FTIPKEQYTII 82
+ P VV L T C + I W+ + P+
Sbjct 354 VVKPRDQVVALGRTVTFQC-------EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFS 406
Query 83 NRTASSVTFTDIASLNIQL----TCNILTFGQLEQNVYGITIISGLPP----EKPKN--- 131
+T T++ ++ T N+ + + +I+ PP + P N
Sbjct 407 VSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTV 466
Query 132 -------LSCIVNEGKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSC- 182
LSC+ W G + + + E + K +C
Sbjct 467 AVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCI 526
Query 183 --TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
T + IEV G DP P+ P V + +
Sbjct 527 ASTPSGEATWSAYIEVQ-----EFGVPVQPPRPTDPNLI--PSAPSKPEVTDVSRN--TV 577
Query 241 KLTWTNPSIKSVIILKYNIQ-YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
L+W Y I+ + S+W + T ++ LKP Y+F +
Sbjct 578 TLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETS---AIKGLKPNAIYLFLV 634
Query 300 RCMKEDGKGYWSDWSEEASGI----TYEDRPSKAPSFWYKIDPSH-----TQGYRTVQLV 350
R G S S+ T + K H ++++
Sbjct 635 RAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVH 694
Query 351 WKTLPPFEANGKILDYEVTLTR-----WKSHLQNYTVNAT---KLTVNLTNDRYLATLTV 402
W + + I Y++ +S + V + + +
Sbjct 695 WTV---DQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKA 751
Query 403 RNLVGKSDAAVLTI---PACDFQATHPVMDLKAF---PKDNMLWVEWTTPRESVKKY-IL 455
R + A I + + P + + V W P E + +
Sbjct 752 RPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQ 811
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
E+ V + + + L Y + V G G
Sbjct 812 EYKVWCLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSG 861
>sp|P0DSP1|SORL_RAT Sortilin-related receptor OS=Rattus norvegicus
OX=10116 GN=Sorl1 PE=1 SV=1
Length=2215
Score = 127 bits (318), Expect = 2e-28, Method: Composition-based stats.
Identities = 83/482 (17%), Positives = 161/482 (33%), Gaps = 46/482 (10%)
Query 128 KPKNLSCIVNEGKKMRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
K +NL I + + W + + + TS +
Sbjct 1557 KVQNLQWIADFSGDVTLTWTRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTSTVLKV 1616
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDP-VYKVKPNPPHNLSVINSEELSSILKLTWT 245
+V V+ + L KV + + + P+ P NL + + E ++ W
Sbjct 1617 LKP-DTTYQVKVQV-HCLSKVHNTNDFVTLRTPEGLPDAPRNLQLSLNSEEEGVILGHWA 1674
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P +I +Y ++Y + W+ + +S +++L Y R+ +
Sbjct 1675 PPVHTHGLIREYIVEYSRSGSKMWASQR-----AASNSTEIKNLLLNALYTVRVAAVTSR 1729
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G G WSD S T + + +AP+ + T+ + + + K+
Sbjct 1730 GIGNWSD---SKSITTTKGKVIQAPNI-HIDSYDENSLSFTLTM--------DGDIKVNG 1777
Query 366 YEVT-LTRWKSHLQNY--------TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
Y V + +H Q + + K++ + Y + + +G S A I
Sbjct 1778 YVVNLFWSFDAHKQEKKTLNFRGGSSLSHKVSNLTAHTSYEVSAWAKTDLGDSPLAFEHI 1837
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
P + KA + + WT P+ V Y + +
Sbjct 1838 LTRGISPPAPSLKAKAINQ-TAVECIWTGPKNVV--YGIFYATSFLDLYRNPKSLTTSLH 1894
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP--TVRTKKVGKNE 534
+ ++ + YL V + P S +K P S+ P + ++GK
Sbjct 1895 NKTVIV----SKDEQYLFLVRVLIP--YQGPSSDYVVVKMIPDSRLPPRHLHAVQIGKTS 1948
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET---AVNVDSSHTEYTLSSLTSDTLYMVR 591
AV++W+ P D + + Y I + +I V +S EY+LS L Y +
Sbjct 1949 AVIKWES-PYDSPDQDLF-YAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHII 2006
Query 592 MA 593
+
Sbjct 2007 VQ 2008
Score = 106 bits (263), Expect = 8e-22, Method: Composition-based stats.
Identities = 99/631 (16%), Positives = 190/631 (30%), Gaps = 67/631 (11%)
Query 45 TAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSV-TFTDIASLNIQLTC 103
+A CV + ++ +I K T N+T++ + + +++
Sbjct 1583 SASCVY-------------NVYYRVVGESIWKTLETHSNKTSTVLKVLKPDTTYQVKVQV 1629
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNL--SCIVNEGKKMRCEWDGGRETH-LETNFTL 160
+ L+ + + GL P+ P+NL S E + W TH L + +
Sbjct 1630 HCLSKVHNTNDFVTLRTPEGL-PDAPRNLQLSLNSEEEGVILGHWAPPVHTHGLIREYIV 1688
Query 161 KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVY- 218
+ + K ++R S + + + V V A + G SD +
Sbjct 1689 EYSRSGSKMW--ASQRAASNSTEI-KNLLLNALYTVRVAAVTSRGIGNWSDSKSITTTKG 1745
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
KV P N+ + + +E S LT + + Y + + + +
Sbjct 1746 KVIQAP--NIHIDSYDENSLSFTLT----MDGDIKVNGYVVNLFWSFDAHKQEKKTLNFR 1799
Query 279 S-TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
+ S V +L T Y + G +T P I+
Sbjct 1800 GGSSLSHKVSNLTAHTSYEVSAWAKTDLGDSPL----AFEHILTRGISPPAPSLKAKAIN 1855
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL 397
+ V+ +W P G + Y + + ++ T + TV ++ D
Sbjct 1856 QT------AVECIWTG-PKNVVYG--IFYATSFLDLYRNPKSLTTSLHNKTVIVSKDEQY 1906
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILE 456
L + + ++ + + P L A ++W +P +S L
Sbjct 1907 LFLVRVLIPYQGPSSDYVVVKMIPDSRLPPRHLHAVQIGKTSAVIKWESPYDS-PDQDLF 1965
Query 457 WCVLSDKAPCITD--WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+ + TD ++ Y L Y I V SIK
Sbjct 1966 YAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHIIVQLGNMS---KDSSIKITT 2022
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLP-VDVQNGFIRNYTIFYRTIIGNETAVNVDSS 573
P + +L W L + Q R Y I N TA +++
Sbjct 2023 ---VSLSAPDALKIITENDHVLLFWKSLALKEKQFNETRGYEIHMFDSAVNLTAYLGNTT 2079
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGK-------------DGPEFTFTTPKFAQGEIEA 620
+ +S+L Y + A G + ++ A
Sbjct 2080 DNFFKVSNLKMGHNYTFTVQARCLFGSQICGEPAVLLYDELSSGGDATVVQTARSTDVAA 2139
Query 621 IVVPVCLAFLLTTLLGVLFCFNKRDLIKKHI 651
+VVP+ LL+ +G + K ++
Sbjct 2140 VVVPILFLILLSLGVGFAVLYTKHRRLQSSF 2170
Score = 89.1 bits (219), Expect = 1e-16, Method: Composition-based stats.
Identities = 80/489 (16%), Positives = 165/489 (34%), Gaps = 52/489 (11%)
Query 347 VQLVWKTLPPFEANGKILDYEVTLTR-----WKSHLQNYTVNATKLTVNLTNDRYLATLT 401
V L W T P + + Y V WK+ + +T L V + Y +
Sbjct 1571 VTLTW-TRPKKMPSASCV-YNVYYRVVGESIWKTLETHSNKTSTVLKVLKPDTTYQVKVQ 1628
Query 402 VRN-LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM--LWVEWTTP---RESVKKYIL 455
V + +T+ + P + + + W P +++YI+
Sbjct 1629 VHCLSKVHNTNDFVTLRTPEGLPDAPRNLQLSLNSEEEGVILGHWAPPVHTHGLIREYIV 1688
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYL 514
E+ W + + T ++ NL + Y + V V + G G+ +S
Sbjct 1689 EY-----SRSGSKMWASQRAASNSTEIK-NLLLNALYTVRVAAVTSRGIGNWSDSKSITT 1742
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR--NYTI--FYRTIIGNETAVNV 570
+ + P + +N +G I+ Y + F+ + +
Sbjct 1743 TKGKVIQAPNIHIDSYDENSLSFT------LTMDGDIKVNGYVVNLFWSFDAHKQEKKTL 1796
Query 571 D---SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPV-- 625
+ S + +S+LT+ T Y V A TD G T + +
Sbjct 1797 NFRGGSSLSHKVSNLTAHTSYEVSAWAKTDLGDSPLAFEHILTRGISPPAPSLKAKAINQ 1856
Query 626 -CLAFLLTTLLGVLF--CFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQM 682
+ + T V++ + L ++ N P + + + + ++
Sbjct 1857 TAVECIWTGPKNVVYGIFYATSFL---DLYRN-PKSLTTSLHNKTVIVSKDEQYLFLVRV 1912
Query 683 --YSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINT--EGHSSGIGGSSCMSSSR 738
G +D VV++ + + P P L ++ + K + + S + +
Sbjct 1913 LIPYQGPSSDYVVVKMIPDSRLP-PRHLHAVQIGKTSAVIKWESPYDSPDQDLFYAIAVK 1971
Query 739 PSISSSDENESSQNTSSTVQY--STVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDL 796
I +D + ++ +STV+Y S + G H + + S+ S + S P+ L
Sbjct 1972 DLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDAL 2031
Query 797 QLV---DHV 802
+++ DHV
Sbjct 2032 KIITENDHV 2040
>sp|O09030|I13R1_MOUSE Interleukin-13 receptor subunit alpha-1
OS=Mus musculus OX=10090 GN=Il13ra1 PE=2 SV=1
Length=424
Score = 122 bits (305), Expect = 3e-28, Method: Composition-based stats.
Identities = 59/310 (19%), Positives = 105/310 (34%), Gaps = 24/310 (8%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRT-ASSV 89
+ PV L + +C + + N + +HF +++ +
Sbjct 27 TEVQPPVTNLSVSVENLCTIIWTWSPPEGASPNCTLRYFSHFDDQQDKKIAPETHRKEEL 86
Query 90 TFTDIASLNIQLTCNILTFGQLEQNVYG-ITIISGLPPEKPKNLSCIVNEGKKMRCEWDG 148
+ L + C+ + V I+ G P L CI + M+C W
Sbjct 87 PLDEKICLQVGSQCSANESEKPSPLVKKCISPPEGDPESAVTELKCIWHNLSYMKCSWLP 146
Query 149 GRETHLETNFTLKSEWAT-HKFADCKA--KRDTPTSCTVDYSTV--YFVNIEVWVEAENA 203
GR T +T++TL +++ K C+ + +C+ + V F + V + ++
Sbjct 147 GRNTSPDTHYTLYYWYSSLEKSRQCENIYREGQHIACSFKLTKVEPSFEHQNVQIMVKDN 206
Query 204 LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT 263
GK+ VKP+PPH + + + L + W NP L Y ++
Sbjct 207 AGKIRPSCKIVSLTSYVKPDPPH---IKHLLLKNGALLVQWKNPQNFRSRCLTYEVEVNN 263
Query 264 KDASTWSQIPPE----------DTASTRSSFTVQDLKPFTEYVFRIRCMKE----DGKGY 309
+ + E S F + + Y R+R D
Sbjct 264 TQTDRHNILEVEEDKCQNSESDRNMEGTSCFQLPGVLADAVYTVRVRVKTNKLCFDDNKL 323
Query 310 WSDWSEEASG 319
WSDWSE S
Sbjct 324 WSDWSEAQSI 333
Score = 45.2 bits (105), Expect = 0.002, Method: Composition-based stats.
Identities = 40/366 (11%), Positives = 91/366 (25%), Gaps = 46/366 (13%)
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
W+ + + T P S + T+ W N +
Sbjct 16 WTATVGQVAAATEVQPPVTNLSV-------SVENLCTIIWTWSPPEGASPNCTLR----Y 64
Query 370 LTRWKSHLQNYTVNATKLTVNLTNDRYL-ATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+ + T L D + + + +S+ + C
Sbjct 65 FSHFDDQQDKKIAPETHRKEELPLDEKICLQVGSQCSANESEKPSPLVKKCISPPEGDPE 124
Query 429 DLKAFPKDNMLW-------VEWTTPRE---SVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
A + +W W R + W +K+ + +E +
Sbjct 125 S--AVTELKCIWHNLSYMKCSWLPGRNTSPDTHYTLYYWYSSLEKSRQCENIYREGQHIA 182
Query 479 RTYLRGNLAE-SKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVL 537
++ + + + + G P L P ++ + ++
Sbjct 183 CSFKLTKVEPSFEHQNVQIMVKDNAGKIRPSCKIVSLTSYVKPDPPHIKHLLLKNGALLV 242
Query 538 EWDQLPVDVQNGFIRNYTIFY---RTIIGNETAVNVDSSHTE-----------YTLSSLT 583
+W Y + +T N V D + L +
Sbjct 243 QWKN--PQNFRSRCLTYEVEVNNTQTDRHNILEVEEDKCQNSESDRNMEGTSCFQLPGVL 300
Query 584 SDTLYMVRMAAYTDEGGKD-----GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
+D +Y VR+ T++ D + Q + + + + + +L
Sbjct 301 ADAVYTVRVRVKTNKLCFDDNKLWSDWSEAQSIGKEQNSTFYTTMLLTIPVFVAVAVIIL 360
Query 639 FCFNKR 644
+ KR
Sbjct 361 LFYLKR 366
>sp|Q03696|NGCA_CHICK Neuronal-glial cell adhesion molecule OS=Gallus
gallus OX=9031 PE=1 SV=2
Length=1266
Score = 126 bits (315), Expect = 4e-28, Method: Composition-based stats.
Identities = 67/441 (15%), Positives = 126/441 (29%), Gaps = 63/441 (14%)
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPP-HNLSVINSEELSSILKLTWTNPSIKSVI 253
+ A L D + +V PP +L V+ +E ++L+WT +
Sbjct 578 TIQCRASTPL-----DSAEAEAQLRVVGRPPSRDLQVMEVDEH--RVRLSWTPGDDHNSP 630
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
I K+ ++ + D + + L P+ + FR+ + G+G
Sbjct 631 IEKFVVEEEEEREDLQRGFGAADVPGQPWTPPLP-LSPYGRFPFRVVAVNAYGRGEHHAP 689
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
S T P + P + + + W+ LPP N Y V
Sbjct 690 SAP--IETPPAAPERNPGGVHG----EGNETGNLVITWEPLPPQAWNAPWARYRVQWRPL 743
Query 374 KS----------HLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAAVLTI--PAC 419
+ TV+A + V + + N GK A +
Sbjct 744 EEPGGGGPSGGFPWAESTVDAPPVVVGGLPPFSPFQIRVQAVNGAGKGPEATPGVGHSGE 803
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTP------RESVKKY-ILEWCVLSDKAPCITDWQQ 472
D +P + + V WT R ++ + +L W +
Sbjct 804 DLPLVYPENVGVELLNSSTVRVRWTLGGGPKELRGRLRGFRVLYWRLGWVGERSRRQAPP 863
Query 473 EDGTVH---------------------RTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
+ + R L G L Y + V G G P
Sbjct 864 DPPQIPQSPAEDPPPFPPVALTVGGDARGALLGGLRPWSRYQLRVLVFNGRGDGPPSEPI 923
Query 512 AY-LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAVN 569
A+ + P +R +++ + + I Y + Y+ + G+
Sbjct 924 AFETPEGVPGPPEELRVERLDDTALSV----VERRTFKRSITGYVLRYQQVEPGSALPGG 979
Query 570 VDSSHTEYTLSSLTSDTLYMV 590
+ L L + + Y +
Sbjct 980 SVLRDPQCDLRGLNARSRYRL 1000
Score = 99 bits (247), Expect = 5e-20, Method: Composition-based stats.
Identities = 113/724 (16%), Positives = 198/724 (27%), Gaps = 103/724 (14%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKE-QYTIINR-TASSVT 90
P S + T C V + W +P + +Y++ T S+V
Sbjct 517 PRSATAKKGETVTFHC----GATFDPAVTPGELRWLRGGQPLPDDPRYSVAAEMTVSNVD 572
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
+ D ++ C T + + + G PP + L + + ++R W G
Sbjct 573 YGDEGTIQ----CRASTPLDSAEAEAQLRV-VGRPPSRD--LQVMEVDEHRVRLSWTPGD 625
Query 151 ETHLET-NFTLKSEWATHKFADCKAKRDTP-TSCTVDYSTVYFVNIEVWVEAENALGKVT 208
+ + F ++ E D P T + V A NA G+
Sbjct 626 DHNSPIEKFVVEEEEEREDLQRGFGAADVPGQPWTPPLPLSPYGRFPFRVVAVNAYGRGE 685
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSS-ILKLTWTN--PSIKSVIILKYNIQYRTKD 265
H P+ P N ++ E + L +TW P + +Y +Q+R +
Sbjct 686 -HHAPSAPIETPPAAPERNPGGVHGEGNETGNLVITWEPLPPQAWNAPWARYRVQWRPLE 744
Query 266 ASTWSQIPPED----TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+ V L PF+ + R++ + GKG + G +
Sbjct 745 EPGGGGPSGGFPWAESTVDAPPVVVGGLPPFSPFQIRVQAVNGAGKGPE---ATPGVGHS 801
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK-TLPPFEANGKILDYEVTLTR--WKSHLQ 378
ED P P TV++ W P E G++ + V R W
Sbjct 802 GEDLPLVYPENVGV----ELLNSSTVRVRWTLGGGPKELRGRLRGFRVLYWRLGWVGERS 857
Query 379 N-----------------------------YTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
L RY + V N G
Sbjct 858 RRQAPPDPPQIPQSPAEDPPPFPPVALTVGGDARGALLGGLRPWSRYQLRVLVFNGRGDG 917
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLW--VEWTTPRESVKKYILEWCVLSDKAPCI 467
+ P +L+ D+ VE T + S+ Y+L + + +
Sbjct 918 PPSEPIAFETPEGVPGPPEELRVERLDDTALSVVERRTFKRSITGYVLRYQQVEPGSALP 977
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
D L Y + + + P K PPS +
Sbjct 978 GGSVLRDPQCD----LRGLNARSRYRLALPSTPRERPAL--QTVGSTKPEPPSPLWSRFG 1031
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYTLSSLTS 584
+ + + + + +E T+ +SS Y L L
Sbjct 1032 VGGRGGFHGAAVEFGAAQEDD---VEFEVQFMNKSTDEPWRTSGRANSSLRRYRLEGLRP 1088
Query 585 DTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTL---------L 635
T Y V+ G + + + VC +
Sbjct 1089 GTAYRVQFVGRNRSGENVAFWE--SEVQTNGTVVPQPGGGVCTKGWFIGFVSSVVLLLLI 1146
Query 636 GVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVE 695
++ CF KR S ++S +S+ + D F + +E
Sbjct 1147 LLILCFIKR----------------SKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLE 1190
Query 696 IEAN 699
EA
Sbjct 1191 SEAE 1194
>sp|O08680|EPHA3_RAT Ephrin type-A receptor 3 OS=Rattus norvegicus
OX=10116 GN=Epha3 PE=2 SV=1
Length=984
Score = 125 bits (314), Expect = 5e-28, Method: Composition-based stats.
Identities = 47/218 (22%), Positives = 80/218 (37%), Gaps = 23/218 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKA----- 174
PP P+N+ +NE + +W GGR+ K W + C
Sbjct 325 PPSAPRNVISNINE-TSVILDWSWPLDTGGRKDITFNIICKKCGWNVRQCEPCSPNVRFL 383
Query 175 --KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK-PNPPHNLSVI 231
+ + + N ++A N + +++S F V P + I
Sbjct 384 PRQLGLTNTTVTVTDLLAHTNYTFEIDAINGVSELSSPPRQFAAVSITTNQAAPSPVMTI 443
Query 232 NSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ S + L+W P + IIL Y ++Y K + + ++ T+ LK
Sbjct 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQE---QETSYTILRARGTNVTISSLK 500
Query 291 PFTEYVFRIRCMKEDGKGYWS-----DWSEEASGITYE 323
P T YVF+IR G G S + S ++ I+ E
Sbjct 501 PDTTYVFQIRARTAAGYGTNSRKFEFENSPDSFSISGE 538
Score = 108 bits (269), Expect = 1e-22, Method: Composition-based stats.
Identities = 38/205 (19%), Positives = 75/205 (37%), Gaps = 22/205 (11%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL---------EWCVLSDKAPCITDWQQE 473
++ + + + ++W+ P ++ + + W V PC + +
Sbjct 325 PPSAPRNVISNINETSVILDWSWPLDTGGRKDITFNIICKKCGWNVR-QCEPCSPNVRFL 383
Query 474 D---GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTV 525
G + T +L Y + + S + QA PS T+
Sbjct 384 PRQLGLTNTTVTVTDLLAHTNYTFEIDAINGVSELSSPPRQFAAVSITTNQAAPSPVMTI 443
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTS 584
+ + +N L W + + NG I +Y + +Y + + + T T+SSL
Sbjct 444 KKDRTSRNSISLSWQE--PEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKP 501
Query 585 DTLYMVRMAAYTDEG-GKDGPEFTF 608
DT Y+ ++ A T G G + +F F
Sbjct 502 DTTYVFQIRARTAAGYGTNSRKFEF 526
Score = 78.7 bits (192), Expect = 2e-13, Method: Composition-based stats.
Identities = 44/210 (21%), Positives = 69/210 (33%), Gaps = 26/210 (12%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWS--- 270
DP PP + S + + L W+ P + +NI + +
Sbjct 316 DPPSMACTRPPSAPRNVISNINETSVILDWSWPLDTGGRKDITFNIICKKCGWNVRQCEP 375
Query 271 -----QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW---SEEASGITY 322
+ P T ++ TV DL T Y F I + G S S T
Sbjct 376 CSPNVRFLPRQLGLTNTTVTVTDLLAHTNYTFEIDAIN--GVSELSSPPRQFAAVSITTN 433
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
+ PS + ++ L W+ P NG ILDYEV + +YT+
Sbjct 434 QAAPSPVMTIKKDRT-----SRNSISLSWQE--PEHPNGIILDYEVKYYEKQEQETSYTI 486
Query 383 ---NATKLTVNLTN--DRYLATLTVRNLVG 407
T +T++ Y+ + R G
Sbjct 487 LRARGTNVTISSLKPDTTYVFQIRARTAAG 516
Score = 63.7 bits (153), Expect = 7e-09, Method: Composition-based stats.
Identities = 34/237 (14%), Positives = 61/237 (26%), Gaps = 38/237 (16%)
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
RC + S + RP AP + +V L W
Sbjct 305 RCENNYFRAEKDPPSMACT------RPPSAP-----RNVISNINETSVILDWSWPLDTGG 353
Query 360 NGKIL--------DYEVTLTRWKSHLQNYT------VNATKLTVNLTN-DRYLATLTVRN 404
I + V S + N T +L Y + N
Sbjct 354 RKDITFNIICKKCGWNVRQCEPCSPNVRFLPRQLGLTNTTVTVTDLLAHTNYTFEIDAIN 413
Query 405 LVGK--SDA---AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT---TPRESVKKYILE 456
V + S A ++I + + K N + + W P + Y ++
Sbjct 414 GVSELSSPPRQFAAVSITTNQAAPSPVMTIKKDRTSRNSISLSWQEPEHPNGIILDYEVK 473
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
+ ++ T + V +L Y+ + A G G+ +
Sbjct 474 YYEKQEQETSYTILRARGTNVT----ISSLKPDTTYVFQIRARTAAGYGTNSRKFEF 526
>sp|Q05707|COEA1_HUMAN Collagen alpha-1(XIV) chain OS=Homo sapiens
OX=9606 GN=COL14A1 PE=1 SV=3
Length=1796
Score = 126 bits (315), Expect = 5e-28, Method: Composition-based stats.
Identities = 64/423 (15%), Positives = 123/423 (29%), Gaps = 49/423 (12%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
PP L I SE + + WT+ + KY + Y ++ + T S+
Sbjct 354 GPPTEL--ITSEVTARSFMVNWTH---APGNVEKYRVVYYPTRGGKPDEVVVDGTVSST- 407
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI-TYEDRPSKAPSFWYKIDPSHT 341
+++L TEY + + SE G T P + Y +
Sbjct 408 --VLKNLMSLTEYQIAVFAIYAH------TASEGLRGTETTLALPMASDLLLYDVT---- 455
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ------NYTVNATKLTVNLTNDR 395
++++ W +P Y + L T + ++
Sbjct 456 --ENSMRVKWDAVPGAS------GYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPN 507
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL 455
T+TV + G+ + +T + P + N + W + Y +
Sbjct 508 TEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRI 567
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
+ T+ + + T+ L Y I + +Y +G P + +
Sbjct 568 VYNNADG-----TEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTE 622
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT 575
+ P + +V + + W L D + ++ G V +
Sbjct 623 EVP--AQQYLEIDEVTTDSFRVTWHPLSADEG----LHKLMWIPVYGGKTEEVVLKEEQD 676
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLL 635
+ + L T Y V + A DG E T P T++
Sbjct 677 SHVIEGLEPGTEYEVSLLAV----LDDGSESEVVT-AVGTTLDSFWTEPATTIVPTTSVT 731
Query 636 GVL 638
V
Sbjct 732 SVF 734
Score = 115 bits (287), Expect = 1e-24, Method: Composition-based stats.
Identities = 69/539 (13%), Positives = 152/539 (28%), Gaps = 54/539 (10%)
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH 153
+ + +T + + V G L P P+NL R WD
Sbjct 505 LPNTEYTVTVYAMFGEEASDPVTGQETTLALSP--PRNLRISNVGSNSARLTWDP-TSRQ 561
Query 154 LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN 213
+ + + + + + P + + + + G+
Sbjct 562 INGYRIVYNNADGTEINEVEVD---PITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGV 618
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
F P + E + ++TW S + + + + ++
Sbjct 619 FTTEEV-----PAQQYLEIDEVTTDSFRVTWHPLSADEGL---HKLMWIPVYGGKTEEV- 669
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCM----------KEDGKGYWSDWSEEASGITYE 323
+ S ++ L+P TEY + + G S W+E A+ I
Sbjct 670 --VLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPT 727
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN---- 379
+ + + ++++ W ++ + + VT + +
Sbjct 728 TSVTSVFQTGIRNLVVGDETTSSLRVKWDI-----SDSDVQQFRVTYMTAQGDPEEEVIG 782
Query 380 ---YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
+ L + +TV + + ++ P ++ P +
Sbjct 783 TVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWY 842
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV 496
N L + W P VK Y + + +S P + + G T L NL Y + +
Sbjct 843 NRLRITWDPPSSPVKGYRIVYKPVSVPGPTL---ETFVGADINTILITNLLSGMDYNVKI 899
Query 497 TPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
+ G +++ +K ++ K V W Y +
Sbjct 900 FA--SQASGFSDALTGMVK-TLFLGVTNLQAKHVEMTSLCAHWQVHR------HATAYRV 950
Query 557 FYRT-IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFA 614
+ + V T + L D+ Y + + YT +GP + +
Sbjct 951 VIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISV--YTKLQEIEGPSVSIMEKTQS 1007
Score = 79.1 bits (193), Expect = 1e-13, Method: Composition-based stats.
Identities = 73/449 (16%), Positives = 138/449 (31%), Gaps = 65/449 (14%)
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQ 271
+ F + + + PP L + ++++W P Y + +Q
Sbjct 20 VYFCTIVQGQVAPPTRLR--YNVISHDSIQISWKAP---RGKFGGYKLLVTPTSGGKTNQ 74
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED-------------------------- 305
+ ++TA + +Q L P Y +I +D
Sbjct 75 LNLQNTA---TKAIIQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVK 131
Query 306 --GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
+G S S P+ A +D S + G +LV +
Sbjct 132 VVDRGNGSRPSSPEEVKFVCQTPAIA-DIVILVDGSWSIGRFNFRLV-----RHFLENLV 185
Query 364 LDYEVTLTRWKSHLQNYTVNA---TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
++V + + L Y+ + L T D + + G + L +
Sbjct 186 TAFDVGSEKTRIGLAQYSGDPRIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIF 245
Query 421 FQATHP-VMDLKAFPKDNMLWVEWT------TPRESVKKYILEWCVLSDKAPCITDWQQE 473
+ P K +L + P ++++ +E + K + + Q+
Sbjct 246 ENSFKPEAGSRTGVSKIGILITDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEI 305
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK---QAPPSKGPTVRTKKV 530
T++ N+AE V + E +K A + T +V
Sbjct 306 ASEPDSTHVY-NVAEFDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTELITSEV 364
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYT-IFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYM 589
++ W P G + Y ++Y T G V VD + + L +L S T Y
Sbjct 365 TARSFMVNWTHAP-----GNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQ 419
Query 590 VRM---AAYTDEGGKDGPEFTFTTPKFAQ 615
+ + A+T G G E T P +
Sbjct 420 IAVFAIYAHTASEGLRGTETTLALPMASD 448
>sp|P10039|TENA_CHICK Tenascin OS=Gallus gallus OX=9031 GN=TNC
PE=1 SV=2
Length=1808
Score = 125 bits (314), Expect = 6e-28, Method: Composition-based stats.
Identities = 80/471 (17%), Positives = 142/471 (30%), Gaps = 41/471 (9%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
P L+ K + EW + +L + + + D + + +
Sbjct 594 SPPTELTVTNVTDKTVNLEW---KHENLVNEYLVTYVPTSSGGLDLQFTVPGNQTSATIH 650
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V + V A L S ++ + P L + E S +++ W
Sbjct 651 ELEPGVEYFIRVFAI--LKNKKSIPVSARVATYLP--APEGLKFKSVRETS--VQVEWDP 704
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
SI + + +R + +S+ L P +Y + +K +
Sbjct 705 LSIS---FDGWELVFRNMQKKDDNGDITSSLKRPETSYMQPGLAPGQQYNVSLHIVKNNT 761
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
+G T D PS+ + T + W + P E G L Y
Sbjct 762 RG----PGLSRVITTKLDAPSQIE--------AKDVTDTTALITW-SKPLAEIEGIELTY 808
Query 367 ---EVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA 423
+V R L N + + Y TL R +SD A
Sbjct 809 GPKDVPGDRTTIDLSE-DENQYSIGNLRPHTEYEVTLISRRGDMESDPAKEVFVTD---L 864
Query 424 THPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
P + DN + +EW ++ Y +++ +S + + R L
Sbjct 865 DAPRNLKRVSQTDNSITLEWKNSHANIDNYRIKFAPISGGDHTELTVPKGNQATTRATLT 924
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLP 543
G L Y I VT V D +P +I A P + + L W +
Sbjct 925 G-LRPGTEYGIGVTAVRQDRESAPATINAGTDLDNPK---DLEVSDPTETTLSLRWRRPV 980
Query 544 VDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
Y + Y + G + + + T + L L + T Y + + A
Sbjct 981 AKFDR-----YRLTYVSPSGKKNEMEIPVDSTSFILRGLDAGTEYTISLVA 1026
Score = 119 bits (299), Expect = 5e-26, Method: Composition-based stats.
Identities = 89/561 (16%), Positives = 167/561 (30%), Gaps = 78/561 (14%)
Query 50 LKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFG 109
+ + + W + T+P Q+++ +VT + +T + G
Sbjct 1072 YENFVIQVQQSDNPEETW---NITVPGGQHSV------NVTGLKANTP-YNVTLYGVIRG 1121
Query 110 QLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEW-------DGGRETHLETNFTLKS 162
+ +Y + +G PE L+ + W D +++N L+
Sbjct 1122 YRTKPLY-VETTTGAHPEV-GELTVSDITPESFNLSWTTTNGDFDAFTIEIIDSNRLLEP 1179
Query 163 EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 222
A + T +Y ++ +A +A ++ + +
Sbjct 1180 MEFNISGNSRTAHISGLSPSTDFIVYLYGISHGFRTQAISAAATTEAEPEVDNLLV---- 1235
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
S+ +L+WT + + ++ R D S
Sbjct 1236 ----------SDATPDGFRLSWTA---DDGVFDSFVLKIR--DTKRKSDPLELIVPGHER 1280
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
+ + LK TEY + + G S T P K
Sbjct 1281 THDITGLKEGTEYEIELYGVSS---GRRSQPINSV-ATTVVGSP--------KGISFSDI 1328
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV-----NATKLTVNLTNDRYL 397
+ + W ++ Y V+ N TKL + Y
Sbjct 1329 TENSATVSWTP-----PRSRVDSYRVSYVPITGGTPNVVTVDGSKTRTKLVKLVPGVDYN 1383
Query 398 ATLTVRNLVGKS-DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
+ +S + + A D + VM++ D+ W +V YI+
Sbjct 1384 VNIISVKGFEESEPISGILKTALDSPSGLVVMNIT----DSEALATWQPAIAAVDNYIVS 1439
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ S+ P +T Q G L G L + Y + V V S +
Sbjct 1440 Y--SSEDEPEVT--QMVSGNTVEYDLNG-LRPATEYTLRVHAVKDAQKSETLSTQFTTGL 1494
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
P + +V AV+ W + +Y + Y +I G V +D T
Sbjct 1495 DAPK---DLSATEVQSETAVITWRPP-----RAPVTDYLLTYESIDGRVKEVILDPETTS 1546
Query 577 YTLSSLTSDTLYMVRMAAYTD 597
YTL+ L+ T Y V++ A +
Sbjct 1547 YTLTELSPSTQYTVKLQALSR 1567
Score = 108 bits (270), Expect = 1e-22, Method: Composition-based stats.
Identities = 74/476 (16%), Positives = 145/476 (30%), Gaps = 54/476 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRDT-----PT 180
+ P + W E ++ T+ D R T
Sbjct 775 DAPSQIEAKDVTDTTALITWSKPLAE--------IEGIELTYGPKDVPGDRTTIDLSEDE 826
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
+ + EV + + G + SD V+ + P NL + + +
Sbjct 827 NQYSIGNLRPHTEYEVTLISRR--GDMESDPAK--EVFVTDLDAPRNLK--RVSQTDNSI 880
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
L W N I Y I++ +++ + T+ L+P TEY +
Sbjct 881 TLEWKN---SHANIDNYRIKFAPISGGDHTELTVPKGNQATTRATLTGLRPGTEYGIGVT 937
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
+++D + S A+ D P DP+ T T+ L W+
Sbjct 938 AVRQDRE------SAPATINAGTD--LDNPKDLEVSDPTET----TLSLRWR-----RPV 980
Query 361 GKILDYEVTL--TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
K Y +T K + V++T + + T+++ G+ + TI
Sbjct 981 AKFDRYRLTYVSPSGKKNEMEIPVDSTSFILRGLDAGTEYTISLVAEKGRHKSKPTTIKG 1040
Query 419 CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
+ + + + WT + + ++++ V P T G H
Sbjct 1041 STEEEPELGNLSVSETGWDGFQLTWTAADGAYENFVIQ--VQQSDNPEETWNITVPGGQH 1098
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
+ G L + Y +T+ V P ++ P + + + L
Sbjct 1099 SVNVTG-LKANTPYNVTLYGVIRGYRTKPLYVETTTGAHP--EVGELTVSDITPESFNLS 1155
Query 539 WDQLPVDVQNGFIRNYTIFY--RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
W NG +TI + N+ + +S L+ T ++V +
Sbjct 1156 W-----TTTNGDFDAFTIEIIDSNRLLEPMEFNISGNSRTAHISGLSPSTDFIVYL 1206
Score = 106 bits (265), Expect = 4e-22, Method: Composition-based stats.
Identities = 80/509 (16%), Positives = 149/509 (29%), Gaps = 43/509 (8%)
Query 127 EKPK--NLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
E+P+ NLS + W NF ++ + + +
Sbjct 1044 EEPELGNLSVSETGWDGFQLTWT--AADGAYENFVIQVQQSDNPEETWNITVPGGQHSVN 1101
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
V + + + + + P L+V + L+W
Sbjct 1102 VTGLKANTPYNVTLYGV--IRGYRTKPLYVETTTGAHPEV-GELTVSDI--TPESFNLSW 1156
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
T + + I+ D++ + + + + + L P T+++ + +
Sbjct 1157 TT---TNGDFDAFTIE--IIDSNRLLEPMEFNISGNSRTAHISGLSPSTDFIVYLYGISH 1211
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG--K 362
+ ++ T E P P +L W + K
Sbjct 1212 GFRTQ-----AISAAATTEAEPEVDNLLVSDATPDG------FRLSWTADDGVFDSFVLK 1260
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
I D + + + + +T Y L + +S A
Sbjct 1261 IRDTKRKSDPLELIVPGH-ERTHDITGLKEGTEYEIELYGVSSGRRSQPINSV--ATTVV 1317
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
+ + +N V WT PR V Y + + ++ P + DG+ RT L
Sbjct 1318 GSPKGISFSDI-TENSATVSWTPPRSRVDSYRVSYVPITGGTPNVV---TVDGSKTRTKL 1373
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
L Y + + + G E I LK + + +EA+ W
Sbjct 1374 V-KLVPGVDYNVNI--ISVKGFEESEPISGILK-TALDSPSGLVVMNITDSEALATWQPA 1429
Query 543 PVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
V N Y + Y + E V + EY L+ L T Y +R+ A D +
Sbjct 1430 IAAVDN-----YIVSYSSEDEPEVTQMVSGNTVEYDLNGLRPATEYTLRVHAVKDAQKSE 1484
Query 603 GPEFTFTTPKFAQGEIEAIVVPVCLAFLL 631
FTT A ++ A V A +
Sbjct 1485 TLSTQFTTGLDAPKDLSATEVQSETAVIT 1513
Score = 84.1 bits (206), Expect = 5e-15, Method: Composition-based stats.
Identities = 47/285 (16%), Positives = 96/285 (34%), Gaps = 18/285 (6%)
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKL 387
P+ + + +TV L WK N ++ Y T + N T
Sbjct 594 SPPTELTVTNVTD----KTVNLEWKH--ENLVNEYLVTYVPTSSGGLDLQFTVPGNQTSA 647
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
T++ + V ++ + ++ + + K+ ++ + VEW
Sbjct 648 TIHELEPGVEYFIRVFAILKNKKSIPVSARVATYLPAPEGLKFKSV-RETSVQVEWDPLS 706
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
S + L + + K D +Y++ LA + Y +++ V + G
Sbjct 707 ISFDGWELVFRNM-QKKDDNGDITSSLKRPETSYMQPGLAPGQQYNVSLHIVKNNTRGPG 765
Query 508 ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNE 565
S K PS+ + K V A++ W I + Y G+
Sbjct 766 LSRVITTKLDAPSQ---IEAKDVTDTTALITW-----SKPLAEIEGIELTYGPKDVPGDR 817
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
T +++ +Y++ +L T Y V + + + D + F T
Sbjct 818 TTIDLSEDENQYSIGNLRPHTEYEVTLISRRGDMESDPAKEVFVT 862
Score = 78.0 bits (190), Expect = 3e-13, Method: Composition-based stats.
Identities = 69/415 (17%), Positives = 133/415 (32%), Gaps = 33/415 (8%)
Query 417 PACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
D P +L D + +EW V +Y++ + S + G
Sbjct 586 MGIDCSDVSPPTELTVTNVTDKTVNLEWKH-ENLVNEYLVTYVPTSSGGLDLQF--TVPG 642
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
+ L Y I V + + P S + P ++ K V +
Sbjct 643 NQTSATIHE-LEPGVEYFIRVFAILKNKKSIPVSARVATYLPAPEG---LKFKSVRETSV 698
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSS----HTEYTLSSLTSDTLYMVR 591
+EWD L + + + +R + + ++ SS T Y L Y V
Sbjct 699 QVEWDPLSISFD-----GWELVFRNMQKKDDNGDITSSLKRPETSYMQPGLAPGQQYNVS 753
Query 592 MAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFL-----LTTLLGVLFCFNKRDL 646
+ + G TT A +IEA V A + L + G+ + +D+
Sbjct 754 LHIVKNNTRGPGLSRVITTKLDAPSQIEAKDVTDTTALITWSKPLAEIEGIELTYGPKDV 813
Query 647 IKKHIWPNVPDPSKS-HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFP 705
++ + I PHT S+ +V V +++A P
Sbjct 814 PGDRTTIDLSEDENQYSIGNLRPHTEYEVTLISRRGDMESDPAKEVFVTDLDA------P 867
Query 706 EDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYS-TVVH 764
+LK + +S + + + S E + +T + + T +
Sbjct 868 RNLKRVSQTDNSITLEWKNSHANIDNYRIKFAPISGGDHTELTVPKGNQATTRATLTGLR 927
Query 765 SGYRHQVPSVQVFSRSESTQPLLDSE---ERPEDLQLVDHVDGGDGILPRQQYFK 816
G + + V ES +++ + P+DL++ D + + R+ K
Sbjct 928 PGTEYGIGVTAVRQDRESAPATINAGTDLDNPKDLEVSDPTETTLSLRWRRPVAK 982
Score = 52.6 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 32/225 (14%), Positives = 66/225 (29%), Gaps = 24/225 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGG--RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
+ P L + + W + +++ + E +
Sbjct 1407 DSPSGLVVMNITDSEALATWQPAIAAVDNYIVSYSSEDEPEVTQMVSGNTVEYDLNGLRP 1466
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ V A K + F + P +LS +E S +TW
Sbjct 1467 A------TEYTLRVHAVKDAQKSETLSTQF----TTGLDAPKDLSA--TEVQSETAVITW 1514
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
P + Y + Y + D ++ +S+T+ +L P T+Y +++ +
Sbjct 1515 RPPRAP---VTDYLLTYESIDG----RVKEVILDPETTSYTLTELSPSTQYTVKLQALSR 1567
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
+ S + T P ++ T G T+ L
Sbjct 1568 SMR---SKMIQTVFTTTGLLYPYPKDCSQALLNGEVTSGLYTIYL 1609
>sp|O88307|SORL_MOUSE Sortilin-related receptor OS=Mus musculus
OX=10090 GN=Sorl1 PE=1 SV=3
Length=2215
Score = 126 bits (315), Expect = 7e-28, Method: Composition-based stats.
Identities = 80/483 (17%), Positives = 164/483 (34%), Gaps = 48/483 (10%)
Query 128 KPKNLSCIVNEGKKMRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD- 185
K +NL + + W + + + TS +
Sbjct 1557 KVQNLQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTSTVLKV 1616
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
++V V N + T+D + + P+ P NL + + E ++ W
Sbjct 1617 LKPDTTYQVKVQVHCLNKV-HNTNDFVTLR-TPEGLPDAPRNLQLSLNSEEEGVILGHWA 1674
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P +I +Y ++Y + W+ + +S +++L Y R+ +
Sbjct 1675 PPVHTHGLIREYIVEYSRSGSKMWASQR-----AASNSTEIKNLLLNALYTVRVAAVTSR 1729
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G G WSD S T + + +AP+ + T+ + + + K+
Sbjct 1730 GIGNWSD---SKSITTIKGKVIQAPNI-HIDSYDENSLSFTLTM--------DGDIKVNG 1777
Query 366 YEVT-LTRWKSHLQNY--------TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
Y V + +H Q + + +++ + Y + + +G S A I
Sbjct 1778 YVVNLFWSFDAHKQEKKTLSFRGGSALSHRVSNLTAHTSYEISAWAKTDLGDSPLAFEHI 1837
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
P + KA + + WT P+ V Y + + + ++
Sbjct 1838 LTRGSSPPAPSLKAKAINQ-TAVECIWTGPKNVV--YGIFYA-----TSFLDLYRNPKSV 1889
Query 477 VHRTYLRGNL-AESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP--TVRTKKVGKN 533
+ + + ++ + YL V + P S +K P S+ P + +GK
Sbjct 1890 TTSLHNKTVIVSKDEQYLFLVRVLIP--YQGPSSDYVVVKMIPDSRLPPRHLHAVHIGKT 1947
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET---AVNVDSSHTEYTLSSLTSDTLYMV 590
A+++W+ P D + + Y I + +I V +S EY+LS L Y +
Sbjct 1948 SALIKWES-PYDSPDQDLF-YAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHI 2005
Query 591 RMA 593
+
Sbjct 2006 IVQ 2008
Score = 107 bits (266), Expect = 4e-22, Method: Composition-based stats.
Identities = 101/631 (16%), Positives = 192/631 (30%), Gaps = 67/631 (11%)
Query 45 TAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSV-TFTDIASLNIQLTC 103
+A CV + ++ +I K T N+T++ + + +++
Sbjct 1583 SASCVY-------------NVYYRVVGESIWKTLETHSNKTSTVLKVLKPDTTYQVKVQV 1629
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNL--SCIVNEGKKMRCEWDGGRETH-LETNFTL 160
+ L + + GL P+ P+NL S E + W TH L + +
Sbjct 1630 HCLNKVHNTNDFVTLRTPEGL-PDAPRNLQLSLNSEEEGVILGHWAPPVHTHGLIREYIV 1688
Query 161 KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVY- 218
+ + K ++R S + + + V V A + G SD + +
Sbjct 1689 EYSRSGSKMW--ASQRAASNSTEI-KNLLLNALYTVRVAAVTSRGIGNWSDSKSITTIKG 1745
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQ-YRTKDASTWSQIPPEDT 277
KV P N+ + + +E S LT + + Y + + + DA +
Sbjct 1746 KVIQAP--NIHIDSYDENSLSFTLT----MDGDIKVNGYVVNLFWSFDAHKQEKKTLSFR 1799
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
+ S V +L T Y + G +T P I+
Sbjct 1800 GGSALSHRVSNLTAHTSYEISAWAKTDLGDSPL----AFEHILTRGSSPPAPSLKAKAIN 1855
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL 397
+ V+ +W P G + Y + + ++ T + TV ++ D
Sbjct 1856 QT------AVECIWTG-PKNVVYG--IFYATSFLDLYRNPKSVTTSLHNKTVIVSKDEQY 1906
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILE 456
L + + ++ + + P L A ++W +P +S L
Sbjct 1907 LFLVRVLIPYQGPSSDYVVVKMIPDSRLPPRHLHAVHIGKTSALIKWESPYDS-PDQDLF 1965
Query 457 WCVLSDKAPCITD--WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+ + TD ++ Y L Y I V SIK
Sbjct 1966 YAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHIIVQLGNMS---KDSSIKITT 2022
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLP-VDVQNGFIRNYTIFYRTIIGNETAVNVDSS 573
P + +L W L + Q R Y I N TA +++
Sbjct 2023 ---VSLSAPDALKIITENDHVLLFWKSLALKEKQFNETRGYEIHMSDSAVNLTAYLGNTT 2079
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGK-------------DGPEFTFTTPKFAQGEIEA 620
+ +S+L Y + A G + ++ A
Sbjct 2080 DNFFKVSNLKMGHNYTFTVQARCLFGSQICGEPAVLLYDELSSGADAAVIQAARSTDVAA 2139
Query 621 IVVPVCLAFLLTTLLGVLFCFNKRDLIKKHI 651
+VVP+ LL+ +G + K ++
Sbjct 2140 VVVPILFLILLSLGVGFAILYTKHRRLQSSF 2170
Score = 86.8 bits (213), Expect = 7e-16, Method: Composition-based stats.
Identities = 80/514 (16%), Positives = 169/514 (33%), Gaps = 53/514 (10%)
Query 323 EDRPSKAPSFWYKIDPSHTQGYR-TVQLVWKTLPPFEANGKILDYEVTLTR-----WKSH 376
E S + + + T + V L W + + Y V WK+
Sbjct 1546 EKACSDELTVYKVQNLQWTADFSGDVTLTWMRPKKMPSASCV--YNVYYRVVGESIWKTL 1603
Query 377 LQNYTVNATKLTVNLTNDRYLATLTVRN-LVGKSDAAVLTIPACDFQATHPVMDLKAFPK 435
+ +T L V + Y + V + +T+ + P +
Sbjct 1604 ETHSNKTSTVLKVLKPDTTYQVKVQVHCLNKVHNTNDFVTLRTPEGLPDAPRNLQLSLNS 1663
Query 436 DNM--LWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
+ + W P +++YI+E+ W + + T ++ NL +
Sbjct 1664 EEEGVILGHWAPPVHTHGLIREYIVEY-----SRSGSKMWASQRAASNSTEIK-NLLLNA 1717
Query 491 CYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y + V V + G G+ +S + + P + +N +G
Sbjct 1718 LYTVRVAAVTSRGIGNWSDSKSITTIKGKVIQAPNIHIDSYDENSLSFT------LTMDG 1771
Query 550 FIR--NYTI--FYRTIIGNETAVNVD---SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
I+ Y + F+ + + S + +S+LT+ T Y + A TD G
Sbjct 1772 DIKVNGYVVNLFWSFDAHKQEKKTLSFRGGSALSHRVSNLTAHTSYEISAWAKTDLGDSP 1831
Query 603 GPEFTFTTPKFAQGEIEAIVVPV---CLAFLLTTLLGVLF--CFNKRDLIKKHIWPNVPD 657
T + + + + T V++ + L ++ N P
Sbjct 1832 LAFEHILTRGSSPPAPSLKAKAINQTAVECIWTGPKNVVYGIFYATSFL---DLYRN-PK 1887
Query 658 PSKSHIAQWSPHTPPRHNFNSKDQM--YSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFK 715
+ + + + ++ G +D VV++ + + P P L ++ + K
Sbjct 1888 SVTTSLHNKTVIVSKDEQYLFLVRVLIPYQGPSSDYVVVKMIPDSRLP-PRHLHAVHIGK 1946
Query 716 KEKINT--EGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQY--STVVHSGYRHQV 771
+ + S + + I +D + ++ +STV+Y S + G H +
Sbjct 1947 TSALIKWESPYDSPDQDLFYAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHII 2006
Query 772 PSVQVFSRSESTQPLLDSEERPEDLQLV---DHV 802
+ S+ S + S P+ L+++ DHV
Sbjct 2007 VQLGNMSKDSSIKITTVSLSAPDALKIITENDHV 2040
>sp|Q8BYI9|TENR_MOUSE Tenascin-R OS=Mus musculus OX=10090 GN=Tnr
PE=1 SV=2
Length=1358
Score = 124 bits (312), Expect = 1e-27, Method: Composition-based stats.
Identities = 88/583 (15%), Positives = 182/583 (31%), Gaps = 70/583 (12%)
Query 49 VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIA-----SLNIQLTC 103
+ K + A + + ++ ++Y ++ T + + ++ + T
Sbjct 594 IDAPKNLRVGSRTATSLDLEWDNSEAEAQEYKVVYSTLAGEQYHEVLVPKGIGPTTKTTL 653
Query 104 NILTFGQLEQNVYGITIIS--GLPPEKPKNLSCIVN--EGKKMRCEWDGGRETHLETNFT 159
L G YG+ I + P ++ + + ET + +T
Sbjct 654 TDLVPG----TEYGVGISAVMNSKQSIPATMNARTELDSPRDLMVT--ASSETSISLIWT 707
Query 160 LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV--------NIEVWVEAENALGKVTSDH 211
S H + TV + + + AE G+ S
Sbjct 708 KASGPIDHYRITFTPSSGISSEVTVPRDRTSYTLTDLEPGAEYIISITAER--GRQQSLE 765
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTKDASTWS 270
D +P + S SS + +TW++PS +IL Y+ + + +D
Sbjct 766 STVDAFTGFRPIS----HLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDKEED----- 816
Query 271 QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
+ +T+ + L+P TEY+ + + G + SE G P
Sbjct 817 -MLEVLLDATKRHAVLMGLQPATEYIVNLVAV----HGTVT--SEPIVGSITTGI--DPP 867
Query 331 SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV---NATKL 387
+ + ++ + W Y V+ + + +V T+
Sbjct 868 KNITISNVTKD----SLTVSW-----SSPVAPFDYYRVSYRPTQVGRLDSSVVPNTVTEF 918
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
+ +++ ++ G+ ++ + P+ + ++W P
Sbjct 919 AITRLYPATEYEISLNSVRGREESERIC-TLVHTAMDSPMDLIATNITPTEALLQWKAPM 977
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
V+ Y++ + I DG L L S Y +T+ GP
Sbjct 978 GEVENYVIVLTHFAIAGETIL----VDGVSEEFQLVD-LLPSTHYTVTMYATS--GPLMS 1030
Query 508 ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA 567
+I + +V + A++ W I NY + Y++ G+
Sbjct 1031 GTIATNFSTLL-DPPDNLTASEVTRQSALISWQPPRAA-----IENYVLTYKSTDGSRKE 1084
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ VD+ T L L+ +T Y V + A + FTT
Sbjct 1085 LIVDAEDTWIRLEGLSENTDYTVLLQAAQEATRSSLTSTVFTT 1127
Score = 123 bits (307), Expect = 5e-27, Method: Composition-based stats.
Identities = 76/484 (16%), Positives = 149/484 (31%), Gaps = 44/484 (9%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
P++L + + EWDG T + + + + + S
Sbjct 327 APPEDLRVAGISDRSIELEWDG---PMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTIM 383
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ + V A V S+ ++ KV + + + +++ W
Sbjct 384 ELEPGLTYNISVYA------VISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEP 437
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
S + I + K+ S +SF LKP EY+ + +KE
Sbjct 438 ---FSFSFDGWEISFIPKNNEG---GVIAQLPSDVTSFNQTGLKPGEEYIVNVVALKEQA 491
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
+ + S P+ D S T + W P + + +L Y
Sbjct 492 RSPPTSASVSTVI--------DGPTQILVRDVSDTVA----FVEWTP-PRAKVDFILLKY 538
Query 367 EVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
+ ++ +V RY +++ +S+A+ +
Sbjct 539 GLVGGEGGKTTFRLQPPLSQYSVQALRPGSRYEVSISAVRGTNESEASSTQFTT---EID 595
Query 425 HPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
P L +EW ++Y + + L+ + + G +T L
Sbjct 596 APKNLRVGSRTATSLDLEWDNSEAEAQEYKVVYSTLAGEQYHEVLVPKGIGPTTKTTL-T 654
Query 485 NLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
+L Y + ++ V P ++ A + P + + L W
Sbjct 655 DLVPGTEYGVGISAVMNSKQSIPATMNARTELDSPR---DLMVTASSETSISLIW----- 706
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
+G I +Y I + G + V V T YTL+ L Y++ + A + G +
Sbjct 707 TKASGPIDHYRITFTPSSGISSEVTVPRDRTSYTLTDLEPGAEYIISITA--ERGRQQSL 764
Query 605 EFTF 608
E T
Sbjct 765 ESTV 768
Score = 68.0 bits (164), Expect = 3e-10, Method: Composition-based stats.
Identities = 36/213 (17%), Positives = 71/213 (33%), Gaps = 14/213 (7%)
Query 420 DFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
D A P DL+ D + +EW P +V +Y++ + A QQ
Sbjct 322 DCSAVAPPEDLRVAGISDRSIELEWDGPM-AVTEYVISY---QPTALGGLQLQQRVPGDW 377
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
L Y I+V V ++ P + K + P ++ K + + ++
Sbjct 378 SGVTIMELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQG---LQFKTITETTVEVQ 434
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNETAV-NVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
W+ + I + + + S T + + L Y+V + A +
Sbjct 435 WEPFSFSFD-----GWEISFIPKNNEGGVIAQLPSDVTSFNQTGLKPGEEYIVNVVALKE 489
Query 598 EGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFL 630
+ + +T +I V +AF+
Sbjct 490 QARSPPTSASVSTVIDGPTQILVRDVSDTVAFV 522
Score = 66.0 bits (159), Expect = 1e-09, Method: Composition-based stats.
Identities = 39/296 (13%), Positives = 89/296 (30%), Gaps = 25/296 (8%)
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL----QNYTVNA 384
P R+++L W + +Y ++ Q +
Sbjct 328 PPEDLRV----AGISDRSIELEWDGPM------AVTEYVISYQPTALGGLQLQQRVPGDW 377
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
+ +T+ ++V ++ + +T +T + K + + V+W
Sbjct 378 SGVTIMELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTI-TETTVEVQWE 436
Query 445 TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
S + + + +++ I V G L + Y++ V +
Sbjct 437 PFSFSFDGWEISFIPKNNEGGVIAQ---LPSDVTSFNQTG-LKPGEEYIVNVVALKEQAR 492
Query 505 GSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN 564
P S + + V A +EW P + + Y + G
Sbjct 493 SPPTSASVST---VIDGPTQILVRDVSDTVAFVEWTP-PRAKVDFILLKYGLV--GGEGG 546
Query 565 ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
+T + ++Y++ +L + Y V ++A + FTT A +
Sbjct 547 KTTFRLQPPLSQYSVQALRPGSRYEVSISAVRGTNESEASSTQFTTEIDAPKNLRV 602
>sp|P29320|EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo sapiens
OX=9606 GN=EPHA3 PE=1 SV=2
Length=983
Score = 124 bits (310), Expect = 1e-27, Method: Composition-based stats.
Identities = 44/208 (21%), Positives = 75/208 (36%), Gaps = 18/208 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAKR--- 176
PP P+N+ +NE + +W GGR+ K W + C
Sbjct 325 PPSSPRNVISNINE-TSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
Query 177 ----DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKV--KPNPPHNLSV 230
+ + N ++A N + +++S F V + P L++
Sbjct 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + L+W P + IIL Y ++Y K + + ++ T+ LK
Sbjct 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQE---QETSYTILRARGTNVTISSLK 500
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
P T YVF+IR G G S E +
Sbjct 501 PDTIYVFQIRARTAAGYGTNSRKFEFET 528
Score = 106 bits (264), Expect = 4e-22, Method: Composition-based stats.
Identities = 38/206 (18%), Positives = 77/206 (37%), Gaps = 20/206 (10%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW--------CVLSDKAPCITDWQQED 474
++ + + + ++W+ P ++ + + + + PC + +
Sbjct 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
Query 475 ---GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTVR 526
G + T +L Y + V S + QA PS T++
Sbjct 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
+ +N L W + + NG I +Y + +Y + + + T T+SSL D
Sbjct 445 KDRTSRNSISLSWQE--PEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
Query 586 TLYMVRMAAYTDEG-GKDGPEFTFTT 610
T+Y+ ++ A T G G + +F F T
Sbjct 503 TIYVFQIRARTAAGYGTNSRKFEFET 528
Score = 77.6 bits (189), Expect = 3e-13, Method: Composition-based stats.
Identities = 44/210 (21%), Positives = 70/210 (33%), Gaps = 26/210 (12%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWS--- 270
DP PP + + S + + L W+ P + +NI + +
Sbjct 316 DPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEP 375
Query 271 -----QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW---SEEASGITY 322
+ P T ++ TV DL T Y F I + G S S T
Sbjct 376 CSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTN 433
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
+ PS + ++ L W+ P NG ILDYEV + +YT+
Sbjct 434 QAAPSPVLTIKKDRT-----SRNSISLSWQE--PEHPNGIILDYEVKYYEKQEQETSYTI 486
Query 383 ---NATKLTVNLTNDR--YLATLTVRNLVG 407
T +T++ Y+ + R G
Sbjct 487 LRARGTNVTISSLKPDTIYVFQIRARTAAG 516
Score = 61.4 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 33/245 (13%), Positives = 63/245 (26%), Gaps = 40/245 (16%)
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
RC + S + RP +P + +V L W
Sbjct 305 RCENNYFRADKDPPSMACT------RPPSSP-----RNVISNINETSVILDWSWPLDTGG 353
Query 360 N--------GKILDYEVTLTRWKSHLQNYT------VNATKLTVNLTN-DRYLATLTVRN 404
K + + S + N T +L Y + N
Sbjct 354 RKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN 413
Query 405 LVGK--SDA---AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT---TPRESVKKYILE 456
V + S A ++I + + K N + + W P + Y ++
Sbjct 414 GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVK 473
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ ++ T + V +L Y+ + A G G+ + +
Sbjct 474 YYEKQEQETSYTILRARGTNVT----ISSLKPDTIYVFQIRARTAAGYGTNSRKFEF--E 527
Query 517 APPSK 521
P
Sbjct 528 TSPDS 532
>sp|Q4ZHG4|FNDC1_HUMAN Fibronectin type III domain-containing
protein 1 OS=Homo sapiens OX=9606 GN=FNDC1 PE=2 SV=4
Length=1894
Score = 124 bits (311), Expect = 2e-27, Method: Composition-based stats.
Identities = 63/445 (14%), Positives = 132/445 (30%), Gaps = 58/445 (13%)
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
P P ++ ++ LK+TW P + ++ Y + +
Sbjct 36 SVDHPLKPRHVKLL---STKMGLKVTWDPPKDATSRPVE---HYNIAYGKSLKSLKYIKV 89
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGK------------GYWSD--------WSEEA 317
+ SF ++D++P Y + G G W +
Sbjct 90 NAETYSFLIEDVEPGVVYFVLLTAENHSGVSRPVYRAESPPGGEWIEIDGFPIKGPGPFN 149
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL------PPFEANGKILDYEVTLT 371
+T ++ P+K + + + WK P + G +L Y +
Sbjct 150 ETVTEKEVPNKPLRVRVR------SSDDRLSVAWKAPRLSGAKSPRRSRGFLLGYGESGR 203
Query 372 RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA------AVLTIPACDFQATH 425
+ ++ + Y+ +L N G+S I D
Sbjct 204 KMNYVPLTRDERTHEIKKLASESVYVVSLQSMNSQGRSQPVYRAALTKRKISEEDELDVP 263
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKKYIL---EWCVLSDKAPCITDWQQEDGTVHRTYL 482
+ ++ + + V W P +K ++ ++ V + + W + +R L
Sbjct 264 DDISVRVMSSQS-VLVSWVDPVLEKQKKVVASRQYTVRYREKGELARWDYK-QIANRRVL 321
Query 483 RGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKV--GKNEAVLE 538
NL Y V + G S+ ++ P+ P + V
Sbjct 322 IENLIPDTVYEFAVRISQGERDGKWSTSVFQRTPESAPTTAPENLNVWPVNGKPTVVAAS 381
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGN--ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
WD LP G ++ Y + Y + ++ T + L Y+ ++ A
Sbjct 382 WDALP--ETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATN 439
Query 597 DEGGKDGPEFTFTT-PKFAQGEIEA 620
G + P ++ ++E
Sbjct 440 RRGLGPHSKAFIVAMPTTSKADVEQ 464
Score = 85.7 bits (210), Expect = 2e-15, Method: Composition-based stats.
Identities = 62/325 (19%), Positives = 108/325 (33%), Gaps = 37/325 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLET-----NFTLKSEWATHKFADCKAKRDTP 179
P KP + ++ + + W R + ++ F L + K RD
Sbjct 157 VPNKPLRVRVRSSDDR-LSVAWKAPRLSGAKSPRRSRGFLLGYGESGRKMNYVPLTRD-- 213
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK------PNPPHNLSVINS 233
V +++ N+ G+ S + + K K + P ++SV
Sbjct 214 ERTHEIKKLASESVYVVSLQSMNSQGR--SQPVYRAALTKRKISEEDELDVPDDISV--R 269
Query 234 EELSSILKLTWTNPSIKSVIIL----KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
S + ++W +P ++ + +Y ++YR K +++L
Sbjct 270 VMSSQSVLVSWVDPVLEKQKKVVASRQYTVRYREKGELARWDYKQ----IANRRVLIENL 325
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ- 348
P T Y F +R + + G WS T E P+ AP ++ G TV
Sbjct 326 IPDTVYEFAVRISQGERDG---KWSTSVFQRTPESAPTTAPEN---LNVWPVNGKPTVVA 379
Query 349 LVWKTLPPFEA--NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT--NDRYLATLTVRN 404
W LP E IL Y L + + Y + T V+ +RYL + N
Sbjct 380 ASWDALPETEGKVKEYILSYAPALKPFGAKSLTYPGDTTSALVDGLQPGERYLFKIRATN 439
Query 405 LVGKSDAAVLTIPACDFQATHPVMD 429
G + I A + V
Sbjct 440 RRGLGPHSKAFIVAMPTTSKADVEQ 464
Score = 61.8 bits (148), Expect = 3e-08, Method: Composition-based stats.
Identities = 42/214 (20%), Positives = 72/214 (34%), Gaps = 32/214 (15%)
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVI 231
+D C++ + +F + N L K + P N++V+
Sbjct 1616 TYLNKDPSAPCSLTDALDHFQVDSLDEIIPNDLKKSDLPPQH----------APRNITVV 1665
Query 232 NSEELSSILKLTWTNPSIKSVII--LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
E S + + W + V+ L Y+ Y + WS AS+ + +++L
Sbjct 1666 AVEGCHSFVIVDWDKATPGDVVTGYLVYSASYEDFIRNKWSTQ-----ASSVTHLPIENL 1720
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED------RPSKAPSFWYKIDPSHT-- 341
KP T Y F+++ G G S S +T D RP W H
Sbjct 1721 KPNTRYYFKVQAQNPHGYGPI---SPSVSFVTESDNPLLVVRPPGGEPIWIPFAFKHDPS 1777
Query 342 ----QGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
G + V+ W L Y++ L+
Sbjct 1778 YTDCHGRQYVKRTWYRKFVGVVLCNSLRYKIYLS 1811
Score = 50.6 bits (119), Expect = 8e-05, Method: Composition-based stats.
Identities = 20/121 (17%), Positives = 41/121 (34%), Gaps = 11/121 (9%)
Query 416 IPACDFQATHPVMDLKAFPKD---NMLWVEWT--TPRESVKKYILEWCVLSDKAPCITDW 470
+ D H ++ + + + V+W TP + V Y++ S + W
Sbjct 1648 LKKSDLPPQHAPRNITVVAVEGCHSFVIVDWDKATPGDVVTGYLVY--SASYEDFIRNKW 1705
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKV 530
+ +V + NL + Y V G G +++ + S P + +
Sbjct 1706 STQASSVTHLPI-ENLKPNTRYYFKVQAQNPHGYGPISPSVSFVTE---SDNPLLVVRPP 1761
Query 531 G 531
G
Sbjct 1762 G 1762
Score = 47.2 bits (110), Expect = 8e-04, Method: Composition-based stats.
Identities = 26/145 (18%), Positives = 49/145 (34%), Gaps = 14/145 (10%)
Query 517 APPSKGP-TVRTKKVGK--NEAVLEWDQLPVDVQNGFIRNYTIF---YRTIIGNETAVNV 570
PP P + V + +++WD + Y ++ Y I N+ +
Sbjct 1653 LPPQHAPRNITVVAVEGCHSFVIVDWD---KATPGDVVTGYLVYSASYEDFIRNKWSTQ- 1708
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAI--VVPVCL 627
SS T + +L +T Y ++ A G P +F T + P+ +
Sbjct 1709 ASSVTHLPIENLKPNTRYYFKVQAQNPHGYGPISPSVSFVTESDNPLLVVRPPGGEPIWI 1768
Query 628 AFLLTTLLGVLFCFNKRDLIKKHIW 652
F C + R +K+ +
Sbjct 1769 PFAFKHDPSYTDC-HGRQYVKRTWY 1792
>sp|P42701|I12R1_HUMAN Interleukin-12 receptor subunit beta-1
OS=Homo sapiens OX=9606 GN=IL12RB1 PE=1 SV=1
Length=662
Score = 123 bits (307), Expect = 2e-27, Method: Composition-based stats.
Identities = 106/618 (17%), Positives = 192/618 (31%), Gaps = 61/618 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
P++L C + C W T ++F L+ ++ + A T +
Sbjct 45 SGPRDLRCYRISSDRYECSWQYEGPTAGVSHF-LRCCLSSGRCCYFAAGSATRLQFSDQA 103
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ +WVE+ S + VK PP L I +L+ L++ W
Sbjct 104 GVSVLYTVTLWVESWARNQTEKSPEVTLQLYNSVKYEPP--LGDIKVSKLAGQLRMEWET 161
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P + +++ ++RT +S W S + L+ F++R +
Sbjct 162 PDNQVGAEVQF--RHRTP-SSPWKLGDCGPQDDDTESC-LCPLEMNVAQEFQLRRRQLGS 217
Query 307 KGY-WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG---K 362
+G WS WS + E+ P P + ++ G R + L + G
Sbjct 218 QGSSWSKWSSPV-CVPPENPPQ--PQVRFSVEQLGQDGRRRLTLKEQPTQLELPEGCQGL 274
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVN-------LTNDRYLATLTVRNLVGKSDAAVLT 415
EVT + H+ + A L+ Y + N G
Sbjct 275 APGTEVTYR-LQLHMLSCPCKAKATRTLHLGKMPYLSGAAYNVAVISSNQFGPGLNQTWH 333
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
IPA + M W R Y +EW + T
Sbjct 334 IPADTHTEPVALNISVGTNGTTMYW----PARAQSMTYCIEWQPVGQDGGLATCSLTAPQ 389
Query 476 --------TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL----------KQA 517
T + G + + KCY IT+ PE + + +
Sbjct 390 DPDPAGMATYSWSRESGAMGQEKCYYITIFA-----SAHPEKLTLWSTVLSTYHFGGNAS 444
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTE 576
V K + ++W + G ++ Y + R + + V + T+
Sbjct 445 AAGTPHHVSVKNHSLDSVSVDWAPSLLSTCPGVLKEYVVRCRDEDSKQVSEHPVQPTETQ 504
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLG 636
TLS L + Y V++ A T G + ++ L L+ LL
Sbjct 505 VTLSGLRAGVAYTVQVRADTA--WLRGVWSQPQRFSIEVQVSDWLIFFASLGSFLSILLV 562
Query 637 VLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEI 696
+ + + +H+ P +P P S ++ P + + + + + VVE+
Sbjct 563 GVLGYLGLNRAARHLCPPLPTPCASSAIEF-PGGKETWQWINPVDFQEEASLQEALVVEM 621
Query 697 --------EANDKKPFPE 706
E +K PE
Sbjct 622 SWDKGERTEPLEKTELPE 639
>sp|O55005|ROBO1_RAT Roundabout homolog 1 OS=Rattus norvegicus
OX=10116 GN=Robo1 PE=1 SV=1
Length=1651
Score = 124 bits (310), Expect = 2e-27, Method: Composition-based stats.
Identities = 104/644 (16%), Positives = 195/644 (30%), Gaps = 111/644 (17%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P + V + + C + + F W+ + +PK +Y I + +
Sbjct 268 PSNLAVTVDDSAEFKCEARGDPVPTFG-------WRKDDGELPKSRYEIRDDHTLKIRKV 320
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLPPE---KPKNLSCIVNEGKKMRCE---- 145
+ G+ E + T+ PP KP++ + +CE
Sbjct 321 TAGDMGSYTCVAENMVGKAEAS---ATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGN 377
Query 146 ------WDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
W RE F+ + ++ +F+ + T T+ Y++ +
Sbjct 378 PQPAIFWR--REGSQNLLFSYQPPQSSSRFSVSQTGDLTVTN-VQRSDVGYYICQTL--- 431
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLS---VINSEELSSILKLT------------W 244
N G + + + PP + V + + L L+ W
Sbjct 432 --NVAGSI-ITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTLTLSCVATGSPVPTILW 488
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
V++ + + + ++ + + R + T
Sbjct 489 RK---DGVLVSTQDSRIKQLESGVLQIRYAKLGDTGRYTCT---------------ASTP 530
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS----HTQGYRTVQLVWKTL--PPFE 358
G+ WS + E P PS TV L+W+
Sbjct 531 SGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLLWQPNLNSGAT 590
Query 359 ANGKILD--YEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
I++ + + W++ +N + N YL + N G SD + ++
Sbjct 591 PTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISD 650
Query 417 PACDFQATHPVMDL------------------KAFPKDNMLWVEWTTPRESVKKYILEWC 458
P + + + V WT ++S +YI +
Sbjct 651 PVKTQDVPPTTQGVDHKQVQRELGNVVLHLHNPTILSSSSVEVHWTVDQQS--QYIQGYK 708
Query 459 VLSDKAP---CITDW---QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK- 511
+L + ++W + T + + L + Y I P + + G+ IK
Sbjct 709 ILYRPSGASHGESEWLVFEVRTPTKNSVVIPD-LRKGVNYEIKARPFFNEFQGADSEIKF 767
Query 512 AYLKQAPPSKGP---TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA- 567
A + PS P TV ++ W P D QNG ++ Y ++ +GNET
Sbjct 768 AKTLEERPSAPPRSVTVSKNDGNGTAILVTWQPPPEDTQNGMVQEYKVW---CLGNETRY 824
Query 568 ---VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
VD S + L Y V +AA T G E F
Sbjct 825 HINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGPGVKSEPQF 868
Score = 120 bits (300), Expect = 3e-26, Method: Composition-based stats.
Identities = 80/533 (15%), Positives = 145/533 (27%), Gaps = 82/533 (15%)
Query 30 YISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNH-------FTIPKEQYTII 82
+ P VV L T C + I W+ + P+
Sbjct 354 VVKPRDQVVALGRTVTFQC-------EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFS 406
Query 83 NRTASSVTFTDIASLNIQL----TCNILTFGQLEQNVYGITIISGLPP----EKPKN--- 131
+T T++ ++ T N+ + + +I+ PP + P N
Sbjct 407 VSQTGDLTVTNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTV 466
Query 132 -------LSCIVNEGKKMRCEW--DGGRETHLETNF--TLKSEWATHKFADCKAKRDTPT 180
LSC+ W DG + ++ R T T
Sbjct 467 AVDGTLTLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLESGVLQIRYAKLGDTGRYTCT 526
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
+ T + IEV G DP P+ P V + + +
Sbjct 527 ASTPSGEATWSAYIEVQ-----EFGVPVQPPRPTDPNLI--PSAPSKPEVTDV--SKNTV 577
Query 241 KLTWTNPSIKSVIILKYNIQ-YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
L W Y I+ + S+W + +F ++ LKP Y+F +
Sbjct 578 TLLWQPNLNSGATPTSYIIEAFSHASGSSWQTVAEN---VKTETFAIKGLKPNAIYLFLV 634
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS------------HTQGYRTV 347
R G SD S+ + + +D P +K +V
Sbjct 635 RAANAYGI---SDPSQISDPVKTQDVPPTTQGVDHKQVQRELGNVVLHLHNPTILSSSSV 691
Query 348 QLVWKTLPPFEANGKILDYEVTLTR-WKSHLQNY-------TVNATKLTVNLTNDRYLAT 399
++ W + + I Y++ SH ++ T + +
Sbjct 692 EVHWTV---DQQSQYIQGYKILYRPSGASHGESEWLVFEVRTPTKNSVVIPDLRKGVNYE 748
Query 400 LTVRNLVGKSDAAVLTI---PACDFQATHPVMDLKAF---PKDNMLWVEWTTPRESVKKY 453
+ R + A I + + + P + + V W P E +
Sbjct 749 IKARPFFNEFQGADSEIKFAKTLEERPSAPPRSVTVSKNDGNGTAILVTWQPPPEDTQNG 808
Query 454 -ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
+ E+ V + + + L Y + V GPG
Sbjct 809 MVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGPG 861
>sp|Q05546|TENR_RAT Tenascin-R OS=Rattus norvegicus OX=10116 GN=Tnr
PE=1 SV=1
Length=1356
Score = 123 bits (309), Expect = 2e-27, Method: Composition-based stats.
Identities = 78/483 (16%), Positives = 151/483 (31%), Gaps = 45/483 (9%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
P++L + + EWDG T + + + + + + S
Sbjct 328 PPEDLRVAGISDRSIELEWDG---PMAVTEYVISYQPSLGGLQ-LQQRVPGDWSGVTITE 383
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP 247
+ + V A V S+ ++ KV + + + +++ W
Sbjct 384 LEPGLTYNISVYA------VISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEP- 436
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
S + I + K+ S +SF LKP EY+ + +KE +
Sbjct 437 --FSFSFDGWEISFTPKNNEG---GVIAQLPSDVTSFNQTGLKPGEEYIVNVVALKEQAR 491
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
G + S P+ D S T + W P + + +L Y
Sbjct 492 GPPTSASVSTVI--------DGPTQILVRDVSDTVA----FVEWTP-PRAKVDFILLKYG 538
Query 368 VTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATH 425
+ ++ +V RY +++ +SDA+ +
Sbjct 539 LVGGEGGKTTFRLQPPLSQYSVQALRPGSRYEVSISAVRGTNESDASSTQFTT---EIDA 595
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
P L +EW ++Y + + L+ + + G +T L +
Sbjct 596 PKNLRVGSRTATSLDLEWDNSEAEAQEYKVVYSTLAGEQYHEVLVPKGIGPTTKTTL-TD 654
Query 486 LAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
L Y + ++ V P ++ A + P + + L W
Sbjct 655 LVPGTEYGVGISAVMNSKQSIPATMNARTELDSPR---DLMVTASSETSISLIW-----T 706
Query 546 VQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+G I +Y I + G + V V T YTL+ L Y++ + A + G + E
Sbjct 707 KASGPIDHYRITFTPSSGISSEVTVPRDRTSYTLTDLEPGAEYIISITA--ERGRQQSLE 764
Query 606 FTF 608
T
Sbjct 765 STV 767
Score = 122 bits (306), Expect = 6e-27, Method: Composition-based stats.
Identities = 84/580 (14%), Positives = 177/580 (31%), Gaps = 65/580 (11%)
Query 49 VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIA-----SLNIQLTC 103
+ K + A + + ++ ++Y ++ T + + ++ + T
Sbjct 593 IDAPKNLRVGSRTATSLDLEWDNSEAEAQEYKVVYSTLAGEQYHEVLVPKGIGPTTKTTL 652
Query 104 NILTFGQLEQNVYGITIIS--GLPPEKPKNLSCIVN--EGKKMRCEWDGGRETHLETNFT 159
L G YG+ I + P ++ + + ET + +T
Sbjct 653 TDLVPG----TEYGVGISAVMNSKQSIPATMNARTELDSPRDLMVT--ASSETSISLIWT 706
Query 160 LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV--------NIEVWVEAENALGKVTSDH 211
S H + TV + + + AE G+ S
Sbjct 707 KASGPIDHYRITFTPSSGISSEVTVPRDRTSYTLTDLEPGAEYIISITAER--GRQQSLE 764
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTKDASTWS 270
D +P + S SS + +TW++PS +IL Y+ +
Sbjct 765 STVDAFTGFRPIS----HLHFSHVTSSSVNITWSDPSPPADRLILNYSPR------DEEE 814
Query 271 QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
++ +T+ + L+P TEY+ + + G + SE G P
Sbjct 815 EMMEVLLDATKRHAVLMGLQPATEYIVNLVAV----HGTVT--SEPIVGSITTGI--DPP 866
Query 331 SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN 390
+ + ++ + W +Y + + T+ T+
Sbjct 867 KNITISNVTKD----SLTVSWSPPVAPFDY---YEYPIDHPSGRLDSSVVPNTVTEFTIT 919
Query 391 LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV 450
+++ ++ G+ ++ + P+ + ++W P V
Sbjct 920 RLYPASQYEISLNSVRGREESERIC-TLVHTAMDSPMDLIATNITPTEALLQWKAPMGEV 978
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
+ Y++ + I DG L L Y +T+ +
Sbjct 979 ENYVIVLTHFAMAGETIL----VDGVSEEFQLVD-LLPRTHYTVTMYATSGPLVSGTIAT 1033
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
PP+ + +V + A++ W I NY + Y++ G+ + V
Sbjct 1034 NFSTLLDPPA---NLTASEVTRQSALISWQPPRAA-----IENYVLTYKSTDGSRKELIV 1085
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
D+ T L L+ +T Y V + A + FTT
Sbjct 1086 DAEDTWIRLEGLSENTDYTVLLQAAQEATRSSLTSTIFTT 1125
Score = 106 bits (265), Expect = 5e-22, Method: Composition-based stats.
Identities = 75/480 (16%), Positives = 140/480 (29%), Gaps = 59/480 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDG--GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P+ L + +W+ E +FT K+ A + + +
Sbjct 415 STPQGLQFKTITETTVEVQWEPFSFSFDGWEISFTPKNNEGGV-IAQLPSDVTSFNQTGL 473
Query 185 DYSTVYFVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
Y VN + + +A + V V P L + ++ +
Sbjct 474 KPGEEYIVNVVALKEQARGPPTSAS--------VSTVIDGPTQILV---RDVSDTVAFVE 522
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
WT P K IL ++Y S ++VQ L+P + Y I ++
Sbjct 523 WTPPRAKVDFIL---LKYGLVGGEGGKT--TFRLQPPLSQYSVQALRPGSRYEVSISAVR 577
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
SD S ++ T E AP + T ++ L W EA
Sbjct 578 GT---NESDAS--STQFTTEI---DAPKNLRVGSRTAT----SLDLEWDN-SEAEA---- 620
Query 364 LDYEVTLTRWKSHL--------QNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT 415
+Y+V + T LT + Y ++ S ++
Sbjct 621 QEYKVVYSTLAGEQYHEVLVPKGIGPTTKTTLTDLVPGTEYGVGISAVMN---SKQSIPA 677
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
+ P + + + + WT + Y + + S + +T
Sbjct 678 TMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGISSEVT-----VP 732
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
+Y +L Y+I++T ++ A+ + V +
Sbjct 733 RDRTSYTLTDLEPGAEYIISITAERGRQQSLESTVDAFTG---FRPISHLHFSHVTSSSV 789
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
+ W I NY+ R V +D++ L L T Y+V + A
Sbjct 790 NITWSDPSPPADR-LILNYSP--RDEEEEMMEVLLDATKRHAVLMGLQPATEYIVNLVAV 846
Score = 71.0 bits (172), Expect = 4e-11, Method: Composition-based stats.
Identities = 34/213 (16%), Positives = 68/213 (32%), Gaps = 15/213 (7%)
Query 420 DFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
D A P DL+ D + +EW P + E+ + + QQ
Sbjct 322 DCSAVTPPEDLRVAGISDRSIELEWDGPMA-----VTEYVISYQPSLGGLQLQQRVPGDW 376
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
L Y I+V V ++ P + K + P ++ K + + ++
Sbjct 377 SGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQG---LQFKTITETTVEVQ 433
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNETAV-NVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
W+ + I + + + S T + + L Y+V + A +
Sbjct 434 WEPFSFSFD-----GWEISFTPKNNEGGVIAQLPSDVTSFNQTGLKPGEEYIVNVVALKE 488
Query 598 EGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFL 630
+ + +T +I V +AF+
Sbjct 489 QARGPPTSASVSTVIDGPTQILVRDVSDTVAFV 521
Score = 71.0 bits (172), Expect = 4e-11, Method: Composition-based stats.
Identities = 42/296 (14%), Positives = 91/296 (31%), Gaps = 24/296 (8%)
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ---NYTVNA 384
P R+++L W + +Y ++ LQ +
Sbjct 327 TPPEDLRV----AGISDRSIELEWDGPM------AVTEYVISYQPSLGGLQLQQRVPGDW 376
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
+ +T+ ++V ++ + +T +T + K + + V+W
Sbjct 377 SGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTI-TETTVEVQWE 435
Query 445 TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
S + + + +++ I V G L + Y++ V +
Sbjct 436 PFSFSFDGWEISFTPKNNEGGVIAQ---LPSDVTSFNQTG-LKPGEEYIVNVVALKEQAR 491
Query 505 GSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN 564
G P S + + V A +EW P + + Y + G
Sbjct 492 GPPTSASVST---VIDGPTQILVRDVSDTVAFVEWTP-PRAKVDFILLKYGLV--GGEGG 545
Query 565 ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
+T + ++Y++ +L + Y V ++A D FTT A +
Sbjct 546 KTTFRLQPPLSQYSVQALRPGSRYEVSISAVRGTNESDASSTQFTTEIDAPKNLRV 601
>sp|Q923P0|COKA1_MOUSE Collagen alpha-1(XX) chain OS=Mus musculus
OX=10090 GN=Col20a1 PE=2 SV=3
Length=1320
Score = 123 bits (308), Expect = 3e-27, Method: Composition-based stats.
Identities = 84/515 (16%), Positives = 155/515 (30%), Gaps = 48/515 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P P L + W + + + + + + + P S
Sbjct 374 PLPTPTRLILTHATSSSIHLSWTPAL--YPPLKYLIVWQPSRGGAPK-EVVVEGPVSSME 430
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ V V G S + + L +TW
Sbjct 431 LGNLTSSTEYLVSVLPVYESGVGKSLQGRATTAPLP-----PPGPLTLAAVTPRTLHVTW 485
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
PS + +Y +QY ++ Q + + L+P +Y ++ ++
Sbjct 486 -PPSAG---VTQYLVQYLLATSTGEEQKREVHVG--QPEVLLDGLEPGQDYDVSVQSLRG 539
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
+ SE S + S + T + W+ P +
Sbjct 540 ------PEASEVQSIRARTSALGPP----RHLTFSDVRYNST-CVSWEAQRPVRLV--KV 586
Query 365 DYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
Y ++ S N T T+ + + T+ V ++VLT +A
Sbjct 587 SY-ISSDGSHSGQTQVPGNLTSATLGPLSSSTMYTVRVTCFYLGGGSSVLTGHVTTQKAP 645
Query 425 HPVMDLKAFPKDNMLWVEWTTPRES-VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
P + + + W S V Y ++W L + GT+ L
Sbjct 646 SPGQLSVMELPGDAVKLSWLATALSGVLVYQIKWMPLGEGKAREIS---VPGTLGTATLP 702
Query 484 GNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
G L + Y IT+ Y DG S P S++ A S ++ N + W
Sbjct 703 G-LMKHVEYEITILAYYRDGTRSDPVSLRYTPSAASRSPPSSLALSSETPNSLQVNWTPP 761
Query 543 PVDVQNGFIRNYTIFYR--TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
+G + +Y + Y + G E +++V + + L L S T Y V ++A G
Sbjct 762 -----SGHVLHYRLNYTLASGSGPEKSISVPGTRSHAVLRDLMSATKYRVLVSAVYRAGE 816
Query 601 KDGPEFTFTT-------PKFAQGEIEAIVVPVCLA 628
T+ T P + + +V +A
Sbjct 817 SMAVSATYRTAACPALHPDSSLSGFDLMVAFGLVA 851
Score = 81.8 bits (200), Expect = 2e-14, Method: Composition-based stats.
Identities = 69/354 (19%), Positives = 124/354 (35%), Gaps = 42/354 (12%)
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
R+ C K G+G + A+G D P P+ + + ++ L W
Sbjct 351 RLICQKIQGRG----PVKPAAGTRVLD-PLPTPTRLILTHATSS----SIHLSWTP---- 397
Query 358 EANGKILDYEVTLTRWKSHLQ-----NYTVNATKLTVNLTNDRYLATLTVR--NLVGKSD 410
A L Y + + V++ +L ++ YL ++ + VGKS
Sbjct 398 -ALYPPLKYLIVWQPSRGGAPKEVVVEGPVSSMELGNLTSSTEYLVSVLPVYESGVGKSL 456
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW 470
T + + L V W P V +Y++++ + +
Sbjct 457 QGRATTAPLPPPGPLTLAAVT----PRTLHVTW-PPSAGVTQYLVQYLLATSTGEEQ--- 508
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKV 530
++E L L + Y ++V + +SI+A P + V
Sbjct 509 KREVHVGQPEVLLDGLEPGQDYDVSVQSLRGPEASEVQSIRARTSALGP--PRHLTFSDV 566
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDSSHTEYTLSSLTSDTLYM 589
N + W+ +R + Y + + V + T TL L+S T+Y
Sbjct 567 RYNSTCVSWEAQRP------VRLVKVSYISSDGSHSGQTQVPGNLTSATLGPLSSSTMYT 620
Query 590 VRMAAYTDEGGKDGPEFTFTTPKF-AQGEIEAIVVP---VCLAFLLTTLLGVLF 639
VR+ + GG TT K + G++ + +P V L++L T L GVL
Sbjct 621 VRVTCFYLGGGSSVLTGHVTTQKAPSPGQLSVMELPGDAVKLSWLATALSGVLV 674
>sp|G5EBF1|SAX3_CAEEL Protein sax-3 OS=Caenorhabditis elegans
OX=6239 GN=sax-3 PE=2 SV=1
Length=1273
Score = 123 bits (308), Expect = 3e-27, Method: Composition-based stats.
Identities = 105/660 (16%), Positives = 179/660 (27%), Gaps = 105/660 (16%)
Query 32 SPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIP-KEQYTIINRTASSVT 90
P+ V + + C I WK + +P Y + +
Sbjct 232 EPKDMTVDVGAAVLFDC-------RVTGDPQPQITWKRKNEPMPVTRAYIAKDNRGLRIE 284
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPE---KPKNLSCIVNEGKKMRCEWD 147
+ + G LE + + PP KP + S C
Sbjct 285 RVQPSDEGEYVCYARNPAGTLEAS---AHLRVQAPPSFQTKPADQSVPAGGTATFECT-- 339
Query 148 GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV----WVEA-EN 202
+ E D T + + +V +V A N
Sbjct 340 --LVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEEVRQVDEGAYVCAGMN 397
Query 203 ALGKVTSDHINFDPVYKVKPNPPH--NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQ 260
+ G S V N P ++ + + +++ S IL
Sbjct 398 SAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMV--------GSSAILPCQAS 449
Query 261 YRTKDASTWSQ--IPPEDTAS-----TRSSFTVQDLK-PFT-EYVFRIRCMKEDGKGYWS 311
+ +W + +P + T S + S + DLK P T Y EDG+ WS
Sbjct 450 GKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKKPDTGVYT--CIAKNEDGESTWS 507
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT-----------VQLVWKTLPPFEAN 360
+ +T ED S A F DPS+ T V+L W P
Sbjct 508 ------ASLTVEDHTSNA-QFVRMPDPSNFPSSPTQPIIVNVTDTEVELHW-NAPSTSGA 559
Query 361 GKILDYEVTLTRWK--SHLQNYTVNATKLTVNL----TNDRYLATLTVRNLVGKSDAAVL 414
G I Y + N + + Y+ + N G +V
Sbjct 560 GPITGYIIQYYSPDLGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAENEKGIGTPSVS 619
Query 415 TIPACDFQATHPV------------------------MDLKAFPKDNMLWVEWTTPR--E 448
+ + V ++ + + W + E
Sbjct 620 SALVTTSKPAAQVALSDKNKMDMAIAEKRLTSEQLIKLEEVKTINSTAVRLFWKKRKLEE 679
Query 449 SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD----GP 504
+ Y ++W + Y+ NL Y V P ++
Sbjct 680 LIDGYYIKWR--GPPRTNDNQYVNVTSPSTENYVVSNLMPFTNYEFFVIPYHSGVHSIHG 737
Query 505 GSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTII 562
S+ +APPS P VR + + + W D NG ++ + I
Sbjct 738 APSNSMDVLTAEAPPSLPPEDVRIRMLNLTTLRISWKAPKADGINGILKGFQIVIVGQAP 797
Query 563 GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK--DGPEFTFTTPKFAQGEIEA 620
N + + TL L + Y +R+AA ++ G G + + A
Sbjct 798 NNNRNITTNERAASVTLFHLVTGMTYKIRVAARSNGGVGVSHGTSEVIMNQDTLEKHLAA 857
>sp|P29318|EPHA3_CHICK Ephrin type-A receptor 3 OS=Gallus gallus
OX=9031 GN=EPHA3 PE=1 SV=1
Length=983
Score = 122 bits (306), Expect = 4e-27, Method: Composition-based stats.
Identities = 43/208 (21%), Positives = 75/208 (36%), Gaps = 18/208 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADC------- 172
PP P+N+ +NE + +W GGR+ K ++ C
Sbjct 324 PPSAPRNVISNINE-TSVILDWSWPLDTGGRKDVTFNIICKKCGGSSKICEPCSDNVRFL 382
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK-PNPPHNLSVI 231
+ + + N ++A N + +++ F V P ++VI
Sbjct 383 PRQTGLTNTTVTVVDLLAHTNYTFEIDAVNGVSDLSTLSRQFAAVSITTNQAAPSPITVI 442
Query 232 NSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ S + L+W P + IIL Y ++Y K + + ++ T+ LK
Sbjct 443 RKDRTSRNSVSLSWQEPEHPNGIILDYEVKYYEKQE---QETSYTILRAKSTNVTISGLK 499
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
P T YVF+IR G S E +
Sbjct 500 PDTTYVFQIRARTAARYGTSSRKFEFET 527
Score = 102 bits (253), Expect = 1e-20, Method: Composition-based stats.
Identities = 63/391 (16%), Positives = 136/391 (35%), Gaps = 70/391 (18%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDK--------APCITDWQ--- 471
++ + + + ++W+ P ++ + + + ++ K PC + +
Sbjct 324 PPSAPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGGSSKICEPCSDNVRFLP 383
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTVR 526
++ G + T +L Y + V S S + QA PS +R
Sbjct 384 RQTGLTNTTVTVVDLLAHTNYTFEIDAVNGVSDLSTLSRQFAAVSITTNQAAPSPITVIR 443
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
+ +N L W + + NG I +Y + +Y + + + T T+S L D
Sbjct 444 KDRTSRNSVSLSWQE--PEHPNGIILDYEVKYYEKQEQETSYTILRAKSTNVTISGLKPD 501
Query 586 TLYMVRMAAYTDEGGKDGP---EFTFTTPKFAQGEIEAIVV---------PVCLAFLLTT 633
T Y+ ++ A T EF + F+ + VV + L ++
Sbjct 502 TTYVFQIRARTAARYGTSSRKFEFETSPDSFSISSENSQVVMIAISAAVAIILLTVVVYV 561
Query 634 LLGVLFCFNK----------------------RDLIKKHIWPNVPDPSKSHIAQWSPHTP 671
L+G + K R + H + + P+ + A+
Sbjct 562 LIGRFCGYKKSKHGTDEKRLHFGNGHLKLPGLRTYVDPHTYED-PNQAVHEFAK-----E 615
Query 672 PRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDL--FKKEKINTEGHSSGIG 729
+ S D++ G F +V ++ KK +K+L +K++ + G +S +G
Sbjct 616 LDASNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKAGYTEKQRRDFLGEASIMG 675
Query 730 G---------SSCMSSSRPSISSSDENESSQ 751
++ S+P + ++ E+
Sbjct 676 QFDHPNIIRLEGVVTKSKPVMIVTEYMENGS 706
Score = 76.4 bits (186), Expect = 8e-13, Method: Composition-based stats.
Identities = 47/213 (22%), Positives = 72/213 (34%), Gaps = 24/213 (11%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWS--- 270
DP PP + S + + L W+ P + +NI + S+
Sbjct 315 DPPSMACTRPPSAPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGGSSKICEP 374
Query 271 -----QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE-DGKGYWSDWSEEASGITYED 324
+ P T T ++ TV DL T Y F I + S S T +
Sbjct 375 CSDNVRFLPRQTGLTNTTVTVVDLLAHTNYTFEIDAVNGVSDLSTLSRQFAAVSITTNQA 434
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV-- 382
PS + +V L W+ P NG ILDYEV + +YT+
Sbjct 435 APSP-----ITVIRKDRTSRNSVSLSWQE--PEHPNGIILDYEVKYYEKQEQETSYTILR 487
Query 383 -NATKLTVNLTN--DRYLATLTVRNLV--GKSD 410
+T +T++ Y+ + R G S
Sbjct 488 AKSTNVTISGLKPDTTYVFQIRARTAARYGTSS 520
Score = 65.3 bits (157), Expect = 3e-09, Method: Composition-based stats.
Identities = 35/246 (14%), Positives = 65/246 (26%), Gaps = 42/246 (17%)
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
RC K + S + RP AP + +V L W + P
Sbjct 304 RCEKNYFRSEKDPPSMACT------RPPSAP-----RNVISNINETSVILDW-SWPLDTG 351
Query 360 NGKILDYEVTLTRWKSHL---------------QNYTVNATKLTVNLTN-DRYLATLTVR 403
K + + + + Q N T V+L Y +
Sbjct 352 GRKDVTFNIICKKCGGSSKICEPCSDNVRFLPRQTGLTNTTVTVVDLLAHTNYTFEIDAV 411
Query 404 NLVG-----KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT---TPRESVKKYIL 455
N V A ++I + + K N + + W P + Y +
Sbjct 412 NGVSDLSTLSRQFAAVSITTNQAAPSPITVIRKDRTSRNSVSLSWQEPEHPNGIILDYEV 471
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
++ ++ T + + V L Y+ + A G+ +
Sbjct 472 KYYEKQEQETSYTILRAKSTNVT----ISGLKPDTTYVFQIRARTAARYGTSSRKFEF-- 525
Query 516 QAPPSK 521
+ P
Sbjct 526 ETSPDS 531
>sp|P29319|EPHA3_MOUSE Ephrin type-A receptor 3 OS=Mus musculus
OX=10090 GN=Epha3 PE=1 SV=1
Length=983
Score = 122 bits (306), Expect = 4e-27, Method: Composition-based stats.
Identities = 44/208 (21%), Positives = 75/208 (36%), Gaps = 18/208 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKA----- 174
PP P+N+ +NE + +W GGR+ K W + C
Sbjct 324 PPSAPRNVISNINE-TSVILDWSWPLDTGGRKDITFNIICKKCGWNVRQCEPCSPNVRFL 382
Query 175 --KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK-PNPPHNLSVI 231
+ + + N ++A N + +++S + V P + I
Sbjct 383 PRQLGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQYAAVSITTNQAAPSPVMTI 442
Query 232 NSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ S + L+W P + IIL Y ++Y K + + ++ T+ LK
Sbjct 443 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYQKQE---QETSYTILRARGTNVTISSLK 499
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
P T YVF+IR G G S E +
Sbjct 500 PDTTYVFQIRARTAAGYGTNSRKFEFET 527
Score = 110 bits (275), Expect = 2e-23, Method: Composition-based stats.
Identities = 40/207 (19%), Positives = 77/207 (37%), Gaps = 22/207 (11%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL---------EWCVLSDKAPCITDWQQE 473
++ + + + ++W+ P ++ + + W V PC + +
Sbjct 324 PPSAPRNVISNINETSVILDWSWPLDTGGRKDITFNIICKKCGWNVR-QCEPCSPNVRFL 382
Query 474 D---GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTV 525
G + T +L Y + V S + QA PS T+
Sbjct 383 PRQLGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQYAAVSITTNQAAPSPVMTI 442
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTS 584
+ + +N L W + + NG I +Y + +Y+ + + + T T+SSL
Sbjct 443 KKDRTSRNSISLSWQE--PEHPNGIILDYEVKYYQKQEQETSYTILRARGTNVTISSLKP 500
Query 585 DTLYMVRMAAYTDEG-GKDGPEFTFTT 610
DT Y+ ++ A T G G + +F F T
Sbjct 501 DTTYVFQIRARTAAGYGTNSRKFEFET 527
Score = 76.8 bits (187), Expect = 6e-13, Method: Composition-based stats.
Identities = 43/209 (21%), Positives = 71/209 (34%), Gaps = 24/209 (11%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWS--- 270
DP PP + S + + L W+ P + +NI + +
Sbjct 315 DPPSMACARPPSAPRNVISNINETSVILDWSWPLDTGGRKDITFNIICKKCGWNVRQCEP 374
Query 271 -----QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE--EASGITYE 323
+ P T ++ TV DL T Y F I + + S + S T +
Sbjct 375 CSPNVRFLPRQLGLTNTTVTVTDLLAHTNYTFEIDAVNGVSE-LSSPPRQYAAVSITTNQ 433
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV- 382
PS + ++ L W+ P NG ILDYEV + + +YT+
Sbjct 434 AAPSPVMTIKKDRT-----SRNSISLSWQE--PEHPNGIILDYEVKYYQKQEQETSYTIL 486
Query 383 --NATKLTVNLTN--DRYLATLTVRNLVG 407
T +T++ Y+ + R G
Sbjct 487 RARGTNVTISSLKPDTTYVFQIRARTAAG 515
Score = 64.1 bits (154), Expect = 5e-09, Method: Composition-based stats.
Identities = 35/245 (14%), Positives = 62/245 (25%), Gaps = 40/245 (16%)
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
RC + S RP AP + +V L W
Sbjct 304 RCENNYFRAEKDPPSMAC------ARPPSAP-----RNVISNINETSVILDWSWPLDTGG 352
Query 360 NGKIL--------DYEVTLTRWKSHLQNYT------VNATKLTVNLTN-DRYLATLTVRN 404
I + V S + N T +L Y + N
Sbjct 353 RKDITFNIICKKCGWNVRQCEPCSPNVRFLPRQLGLTNTTVTVTDLLAHTNYTFEIDAVN 412
Query 405 LVGK--SDA---AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT---TPRESVKKYILE 456
V + S A ++I + + K N + + W P + Y ++
Sbjct 413 GVSELSSPPRQYAAVSITTNQAAPSPVMTIKKDRTSRNSISLSWQEPEHPNGIILDYEVK 472
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ ++ T + V +L Y+ + A G G+ + +
Sbjct 473 YYQKQEQETSYTILRARGTNVT----ISSLKPDTTYVFQIRARTAAGYGTNSRKFEF--E 526
Query 517 APPSK 521
P
Sbjct 527 TSPDS 531
>sp|Q60805|MERTK_MOUSE Tyrosine-protein kinase Mer OS=Mus musculus
OX=10090 GN=Mertk PE=1 SV=1
Length=994
Score = 122 bits (305), Expect = 6e-27, Method: Composition-based stats.
Identities = 72/426 (17%), Positives = 143/426 (34%), Gaps = 43/426 (10%)
Query 36 PVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTI-----INRTASSVT 90
V+ H N C + + + I W + + ++I S +
Sbjct 97 IVLSEHKNVKFNCSI---NIPNTYQETAGISWWKDGKELLGAHHSITQFYPDEEGVSIIA 153
Query 91 FTDIASLNIQLTCNILT---FGQLEQNVYGITIIS-GLPP--EKPKNLSCIVNEGKKMRC 144
IAS+ + E I + GLP ++P++++ N + C
Sbjct 154 LFSIASVQRSDNGSYFCKMKVNNREIVSDPIYVEVQGLPYFIKQPESVNVTRNTAFNLTC 213
Query 145 EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
+ G E + W + + +P+ TV T EA N
Sbjct 214 QAVGPPEP-------VNIFWVQNSSRVNEKPERSPSVLTVPGLTE---TAVFSCEAHNDK 263
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK 264
G S ++ + KV P+PP + ++NS S + ++W + +IQ +
Sbjct 264 GLTVSKGVHINI--KVIPSPPTEVHILNSTAHS--ILVSWVPGFDGYSPLQNCSIQVKEA 319
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
D + + +T+++ + +Q L+ Y + C E G WS S T E
Sbjct 320 DRLSNGSVMVFNTSASPHLYEIQQLQALANYSIAVSCRNEIG---WSAVSPWILASTTEG 376
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL-----TRWKSHLQN 379
PS AP I + + + W P +G+++ Y ++ +K +
Sbjct 377 APSVAP---LNITVFLNESNNILDIRWTKPPIKRQDGELVGYRISHVWESAGTYKELSEE 433
Query 380 YTVNATK--LTVNLTNDRYLATLTVRN--LVGKSDAAVLTIPACDFQATHPVMDLKAFPK 435
+ N + + V + N + +G V I + + A
Sbjct 434 VSQNGSWAQIPVQIHNATCTVRIAAITKGGIGPFSEPVNIIIPEHSKVDYAPSSTPAPGN 493
Query 436 DNMLWV 441
+ +++
Sbjct 494 TDSMFI 499
Score = 63.3 bits (152), Expect = 8e-09, Method: Composition-based stats.
Identities = 42/316 (13%), Positives = 92/316 (29%), Gaps = 25/316 (8%)
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATK-LTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
+A G + + S + + LTV + + + N G + + + I
Sbjct 214 QAVGPPEPVNIFWVQNSSRVNEKPERSPSVLTVPGLTETAVFSCEAHNDKGLTVSKGVHI 273
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRE---SVKKYILEWCVLSDKAPCITDWQQE 473
+ + + + + V W + ++ ++ +
Sbjct 274 NIKVIPSPPTEVHILN-STAHSILVSWVPGFDGYSPLQNCSIQVKEADRLSNGSVMVFNT 332
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK-AYLKQAPPSKGP-TVRT-KKV 530
+ H Y L Y I V+ G + A + PS P +
Sbjct 333 SASPH-LYEIQQLQALANYSIAVSCRNEIGWSAVSPWILASTTEGAPSVAPLNITVFLNE 391
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHT-EYTLSSLT-SDTL 587
N + W + P+ Q+G + Y I G ++ + S + + +
Sbjct 392 SNNILDIRWTKPPIKRQDGELVGYRISHVWESAGTYKELSEEVSQNGSWAQIPVQIHNAT 451
Query 588 YMVRMAAYTDEGGKDGPE-FTFTTPKFAQGEIE------------AIVVPVCLAFLLTTL 634
VR+AA T G E P+ ++ + ++ C +
Sbjct 452 CTVRIAAITKGGIGPFSEPVNIIIPEHSKVDYAPSSTPAPGNTDSMFIILGCFCGFILIG 511
Query 635 LGVLFCFNKRDLIKKH 650
L + R +++
Sbjct 512 LILCISLALRRRVQET 527
Score = 48.3 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 37/265 (14%), Positives = 76/265 (29%), Gaps = 30/265 (11%)
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT--PRESV 450
N Y + V N SD + + + P ++ + P E V
Sbjct 165 NGSYFCKMKVNNREIVSDPIYVEVQGLPYFIKQPESV--NVTRNTAFNLTCQAVGPPEPV 222
Query 451 K-KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES 509
++ +++K G + G +
Sbjct 223 NIFWVQNSSRVNEKPERSPSVLTVPGLTETAV------------FSCEAHNDKGLTVSKG 270
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII----GNE 565
+ +K PS V + ++ W +P ++N +I + G+
Sbjct 271 VHINIK-VIPSPPTEVHILNSTAHSILVSW--VPGFDGYSPLQNCSIQVKEADRLSNGSV 327
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVP 624
N +S Y + L + Y + ++ + G P +T + A V P
Sbjct 328 MVFNTSASPHLYEIQQLQALANYSIAVSCRNEIGWSAVSPWILASTTEGAPS-----VAP 382
Query 625 VCLAFLLTTLLGVLFCFNKRDLIKK 649
+ + L +L + IK+
Sbjct 383 LNITVFLNESNNILDIRWTKPPIKR 407
>sp|H2A0L8|FND2_PINMG Fibronectin type III domain-containing protein
2 OS=Margaritifera margaritifera OX=102329 PE=1 SV=1
Length=624
Score = 119 bits (297), Expect = 2e-26, Method: Composition-based stats.
Identities = 67/426 (16%), Positives = 124/426 (29%), Gaps = 27/426 (6%)
Query 82 INRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKK 141
+N+T +S+T S ++ + + P +P NL +
Sbjct 194 VNQTVASITDLYPRSFYKVSVGTVICSTSESSSGAKSLKTPDIIPSEPTNLRVDGTKPNA 253
Query 142 MRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAE 201
+ WD N+T+ + + Y + + V A
Sbjct 254 IALRWDLPLLMGTLANYTIYVTSENGTGFEVAVDPTQVN--AILYDLIEGTRYVISVSAF 311
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
+ G+ P+ P VI ++ + L W P+ + +I Y+I Y
Sbjct 312 SDNGESPKSSSIEVMTDVFVPDMPRFFQVIFVN--TTSVHLVWEPPNPGAGMIRYYSINY 369
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
D+ + + ++ + L+P T Y FR G S + + IT
Sbjct 370 --TDSLYSQFFNFKTPNAKITTAIITGLQPATTYYFRAFAHTGRRAGAGSAVIMQDTDIT 427
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
P + +L W LPP + G + +Y + +
Sbjct 428 VPTVPRE------LYAQKAKNDPPRARLQW--LPPAKTYGSLKNYSIHWGVKNGATRKEE 479
Query 382 VNATKLT----VNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMD----LKAF 433
+ L N + L +N G AA +T P K
Sbjct 480 IEPGLLEWYSDFLDDNTEHEFKLYAQNEKGYGPAATVTHRTPKRDTVVPPNVKVDRKKGK 539
Query 434 PKDNMLWVEWTT---PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
+ +L V W P + V + + + ++ R+ G E+
Sbjct 540 NNETVLVVSWNPITQPGKQVSGFRILYRKFEWVYTGRWSLKEIPDPNARSATIG--VENS 597
Query 491 CYLITV 496
Y V
Sbjct 598 NYSFIV 603
Score = 118 bits (295), Expect = 4e-26, Method: Composition-based stats.
Identities = 71/458 (16%), Positives = 143/458 (31%), Gaps = 49/458 (11%)
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDA-------STWSQIPPEDTASTRSSFTVQ 287
SS + ++W P++ + ++QY+ A T I + ++ ++
Sbjct 143 GNSSSVIVSWDRPNVVGTDVRLDDLQYKVYFAPLDEYGQQTAEAIVFSICSVNQTVASIT 202
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV 347
DL P + Y + S S T + PS+ + +
Sbjct 203 DLYPRSFYKVSV---GTVICSTSESSSGAKSLKTPDIIPSEPTNLRVDGT-----KPNAI 254
Query 348 QLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV----NLTNDRYLATLTVR 403
L W LP G + +Y + +T V+ T++ + RY+ +++
Sbjct 255 ALRWD-LPLLM--GTLANYTIYVTSENGTGFEVAVDPTQVNAILYDLIEGTRYVISVSAF 311
Query 404 NLVGKSD-AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR---ESVKKYILEWCV 459
+ G+S ++ + + F P F + + W P ++ Y + +
Sbjct 312 SDNGESPKSSSIEVMTDVFVPDMPRFFQVIFVNTTSVHLVWEPPNPGAGMIRYYSINY-- 369
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA--DGPGSPESIKAYLKQA 517
+D + T + L + Y G GS I
Sbjct 370 -TDSLYSQFFNFKTPNAKITTAIITGLQPATTYYFRAFAHTGRRAGAGSAV-IMQDTDIT 427
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY 577
P+ + +K + LP G ++NY+I + G ++ E+
Sbjct 428 VPTVPRELYAQKAKNDPPRARLQWLPPAKTYGSLKNYSIHWGVKNGATRKEEIEPGLLEW 487
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP---------------KFAQGEIEAIV 622
L +T + ++ A ++G T TP K E +V
Sbjct 488 YSDFLDDNTEHEFKLYAQNEKGYGPAATVTHRTPKRDTVVPPNVKVDRKKGKNNETVLVV 547
Query 623 VPVCLAFLLTTLLGVLFCFNKRDLIKKHIWP--NVPDP 658
+ + G + K + + W +PDP
Sbjct 548 SWNPITQPGKQVSGFRILYRKFEWVYTGRWSLKEIPDP 585
Score = 108 bits (270), Expect = 4e-23, Method: Composition-based stats.
Identities = 78/492 (16%), Positives = 155/492 (32%), Gaps = 57/492 (12%)
Query 136 VNEGKKMRCEWDGGRETHLETN-----FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY 190
+ + WD + + + ++ A+ + C+V+ +
Sbjct 142 IGNSSSVIVSWDRPNVVGTDVRLDDLQYKVYFA-PLDEYGQQTAEAIVFSICSVNQTVAS 200
Query 191 FVNIEVWVEAENALG------KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
++ + ++G +S + P+ P NL V + + + L W
Sbjct 201 ITDLYPRSFYKVSVGTVICSTSESSSGAKSLKTPDIIPSEPTNLRVDGT--KPNAIALRW 258
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
P + + Y I Y T + T ++ T+ + + DL T YV + +
Sbjct 259 DLPLLM-GTLANYTI-YVTSENGTGFEVA---VDPTQVNAILYDLIEGTRYVISVSAFSD 313
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
+G+ S S +T P P F+ I + T +V LVW+ PP G I
Sbjct 314 NGE---SPKSSSIEVMTDVFVPD-MPRFFQVIFVNTT----SVHLVWE--PPNPGAGMIR 363
Query 365 DYEVTLT------RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
Y + T + N + +T Y + + +
Sbjct 364 YYSINYTDSLYSQFFNFKTPNAKITTAIITGLQPATTYYFRAFAHTGRRAGAGSAVIMQD 423
Query 419 CDFQATHPVMDLKAFPKDN---MLWVEWTTPRE---SVKKYILEWCVLSDKAPCITDWQQ 472
D +L A N ++W P + S+K Y + W V K +
Sbjct 424 TDITVPTVPRELYAQKAKNDPPRARLQWLPPAKTYGSLKNYSIHWGV---KNGATRKEEI 480
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG- 531
E G + L ++ + + G G ++ + P V+ +
Sbjct 481 EPGLLEWY--SDFLDDNTEHEFKLYAQNEKGYGPAATVTHRTPKRDTVVPPNVKVDRKKG 538
Query 532 ---KNEAVLEWDQLPVDVQNGFIRNYTIFYRT----IIGNET-AVNVDSSHTEYTLSSLT 583
+ V+ W+ + + + I YR G + D + T+
Sbjct 539 KNNETVLVVSWNPI--TQPGKQVSGFRILYRKFEWVYTGRWSLKEIPDPNARSATIGVEN 596
Query 584 SDTLYMVRMAAY 595
S+ ++V + Y
Sbjct 597 SNYSFIVVVRGY 608
Score = 74.1 bits (180), Expect = 3e-12, Method: Composition-based stats.
Identities = 49/293 (17%), Positives = 84/293 (29%), Gaps = 29/293 (10%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFT--LKSEWATHKFADCKAKR 176
P+ P+ I + W+ G + N+T L S++ K + K
Sbjct 330 FVPDMPRFFQVIFVNTTSVHLVWEPPNPGAGMIRYYSINYTDSLYSQFFNFKTPNAKITT 389
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
T A + P P L ++
Sbjct 390 AIITGLQPA------TTYYFRAFAHTGRRAGAGSAVIMQDTDITVPTVPRELYAQKAKND 443
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
+L W P+ + Y+I + K+ +T + S F L TE+
Sbjct 444 PPRARLQWLPPAKTYGSLKNYSIHWGVKNGATRKEEIEPGLLEWYSDF----LDDNTEHE 499
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL-- 354
F++ E G G + + T R + P + + W +
Sbjct 500 FKLYAQNEKGYG----PAATVTHRTP-KRDTVVPPNVKVDRKKGKNNETVLVVSWNPITQ 554
Query 355 PPFEANGKILDYE----VTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVR 403
P + +G + Y V RW NA T+ + N Y + VR
Sbjct 555 PGKQVSGFRILYRKFEWVYTGRWSLKEIPDP-NARSATIGVENSNYSFIVVVR 606
>sp|P09759|EPHB1_RAT Ephrin type-B receptor 1 OS=Rattus norvegicus
OX=10116 GN=Ephb1 PE=1 SV=2
Length=984
Score = 120 bits (300), Expect = 2e-26, Method: Composition-based stats.
Identities = 40/201 (20%), Positives = 73/201 (36%), Gaps = 18/201 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH-----LETNFTLKSEWATHKFADCK------ 173
P P+N+ IVNE + EW RET K + C
Sbjct 322 VPSGPRNVISIVNE-TSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFV 380
Query 174 AKRDTPTSCTVDYSTVY-FVNIEVWVEAENALGKVTS-DHINFDPVYKVKPNPPHNLSVI 231
++ T C V S+++ ++A N + + + P + ++
Sbjct 381 PRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIM 440
Query 232 NSEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + + L+W P + IIL Y I+Y K+ ++ S ++ + L+
Sbjct 441 HQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEH---NEFNSSMARSQTNTARIDGLR 497
Query 291 PFTEYVFRIRCMKEDGKGYWS 311
P YV ++R G G +S
Sbjct 498 PGMVYVVQVRARTVAGYGKFS 518
Score = 109 bits (271), Expect = 6e-23, Method: Composition-based stats.
Identities = 54/306 (18%), Positives = 101/306 (33%), Gaps = 34/306 (11%)
Query 424 THPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL-----------SDKAPCITDWQQ 472
++ + + + +EW PRE+ + + + ++ S + +
Sbjct 323 PSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPR 382
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVRT 527
+ G +L Y + + SP S+ QA PS P +
Sbjct 383 QLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQ 442
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT-EYTLSSLTSDT 586
L W Q + NG I +Y I Y NE ++ S T + L
Sbjct 443 VSATMRSITLSWPQ--PEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGM 500
Query 587 LYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGE--------IEAIVVPVCLAFLLTTLLGV 637
+Y+V++ A T G GK + F T + + A + F+++ +
Sbjct 501 VYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAIS 560
Query 638 LFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSD----GNFTDVSV 693
+ C KR K+ ++ + + SP + + + DVS
Sbjct 561 IVCSRKRAYSKEAVYSD--KLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSF 618
Query 694 VEIEAN 699
V+IE
Sbjct 619 VKIEEV 624
Score = 79.1 bits (193), Expect = 1e-13, Method: Composition-based stats.
Identities = 48/279 (17%), Positives = 80/279 (29%), Gaps = 39/279 (14%)
Query 159 TLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN----- 213
T K+ + CKA + + N+ + I
Sbjct 254 TCKAGYEPENSVACKACPAGTFKASQEAEGCSH-------CPSNSRSPSEASPICTCRTG 306
Query 214 -----FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDAS 267
FDP + P + S + + L W P + YNI + A
Sbjct 307 YYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRAD 366
Query 268 TWS--------QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE-EAS 318
S + P T ++ L T Y F I+ + +
Sbjct 367 RRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVN 426
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT-----RW 373
T + PS P I + R++ L W P + NG ILDYE+ +
Sbjct 427 ITTNQAAPSTVP-----IMHQVSATMRSITLSW--PQPEQPNGIILDYEIRYYEKEHNEF 479
Query 374 KSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
S + N ++ Y+ + R + G +
Sbjct 480 NSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFS 518
Score = 61.4 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 27/225 (12%), Positives = 55/225 (24%), Gaps = 30/225 (13%)
Query 310 WSDWSEEASGIT-YEDRPSKAPSFWYKIDPS------HTQGYRTVQLVWKTLPPFEANGK 362
S+ S + T Y P PS ++ L W
Sbjct 294 PSEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDD 353
Query 363 ILDYEV----------TLTRWKSHLQNYTVNA------TKLTVNLTNDRYLATLTVRNLV 406
+ Y + + +R +++ ++ + Y + N V
Sbjct 354 VT-YNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGV 412
Query 407 G-KSDAA----VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
KS + I + + + + + W E IL++ +
Sbjct 413 SSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSW-PQPEQPNGIILDYEIRY 471
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ + T L Y++ V G G
Sbjct 472 YEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGK 516
>sp|P54762|EPHB1_HUMAN Ephrin type-B receptor 1 OS=Homo sapiens
OX=9606 GN=EPHB1 PE=1 SV=1
Length=984
Score = 120 bits (300), Expect = 2e-26, Method: Composition-based stats.
Identities = 40/201 (20%), Positives = 73/201 (36%), Gaps = 18/201 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH-----LETNFTLKSEWATHKFADCK------ 173
P P+N+ IVNE + EW RET K + C
Sbjct 322 VPSGPRNVISIVNE-TSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFV 380
Query 174 AKRDTPTSCTVDYSTVY-FVNIEVWVEAENALGKVTS-DHINFDPVYKVKPNPPHNLSVI 231
++ T C V S+++ ++A N + + + P + ++
Sbjct 381 PRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIM 440
Query 232 NSEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + + L+W P + IIL Y I+Y K+ ++ S ++ + L+
Sbjct 441 HQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEH---NEFNSSMARSQTNTARIDGLR 497
Query 291 PFTEYVFRIRCMKEDGKGYWS 311
P YV ++R G G +S
Sbjct 498 PGMVYVVQVRARTVAGYGKFS 518
Score = 109 bits (271), Expect = 7e-23, Method: Composition-based stats.
Identities = 54/306 (18%), Positives = 101/306 (33%), Gaps = 34/306 (11%)
Query 424 THPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL-----------SDKAPCITDWQQ 472
++ + + + +EW PRE+ + + + ++ S + +
Sbjct 323 PSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPR 382
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVRT 527
+ G +L Y + + SP S+ QA PS P +
Sbjct 383 QLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQ 442
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT-EYTLSSLTSDT 586
L W Q + NG I +Y I Y NE ++ S T + L
Sbjct 443 VSATMRSITLSWPQ--PEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGM 500
Query 587 LYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGE--------IEAIVVPVCLAFLLTTLLGV 637
+Y+V++ A T G GK + F T + + A + F+++ +
Sbjct 501 VYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAIS 560
Query 638 LFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSD----GNFTDVSV 693
+ C KR K+ ++ + + SP + + + DVS
Sbjct 561 IVCSRKRAYSKEAVYSD--KLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSF 618
Query 694 VEIEAN 699
V+IE
Sbjct 619 VKIEEV 624
Score = 79.9 bits (195), Expect = 8e-14, Method: Composition-based stats.
Identities = 54/311 (17%), Positives = 89/311 (29%), Gaps = 50/311 (16%)
Query 127 EKPKNLSCIVNEGKKMR----CEWDGGRETHLETN------FTLKSEWATHKFADCKAKR 176
+ P L C +G+ M C G E T K+ + C +
Sbjct 233 DVPIKLYCN-GDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNS 291
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
+P + T +FDP + P + S
Sbjct 292 RSPAEAS-PICTCRTGYYR----------------ADFDPPEVACTSVPSGPRNVISIVN 334
Query 237 SSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWS--------QIPPEDTASTRSSFTVQ 287
+ + L W P + YNI + A S + P T ++
Sbjct 335 ETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSIS 394
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSE-EASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
L T Y F I+ + + T + PS P I + R+
Sbjct 395 SLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVP-----IMHQVSATMRS 449
Query 347 VQLVWKTLPPFEANGKILDYEVTLT-----RWKSHLQNYTVNATKLTVNLTNDRYLATLT 401
+ L W P + NG ILDYE+ + S + N ++ Y+ +
Sbjct 450 ITLSW--PQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVR 507
Query 402 VRNLVGKSDAA 412
R + G +
Sbjct 508 ARTVAGYGKFS 518
Score = 59.9 bits (143), Expect = 1e-07, Method: Composition-based stats.
Identities = 22/204 (11%), Positives = 51/204 (25%), Gaps = 29/204 (14%)
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV----------TLTRW 373
PS + ++ ++ L W + Y + + +R
Sbjct 321 SVPSGPRNVISIVN------ETSIILEWHPPRETGGRDDVT-YNIICKKCRADRRSCSRC 373
Query 374 KSHLQNYTVNA------TKLTVNLTNDRYLATLTVRNLVG-KSDAA----VLTIPACDFQ 422
+++ ++ + Y + N V KS + I
Sbjct 374 DDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAA 433
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
+ + + + + W E IL++ + + + T
Sbjct 434 PSTVPIMHQVSATMRSITLSW-PQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTAR 492
Query 483 RGNLAESKCYLITVTPVYADGPGS 506
L Y++ V G G
Sbjct 493 IDGLRPGMVYVVQVRARTVAGYGK 516
>sp|Q8CBF3|EPHB1_MOUSE Ephrin type-B receptor 1 OS=Mus musculus
OX=10090 GN=Ephb1 PE=1 SV=1
Length=984
Score = 120 bits (300), Expect = 2e-26, Method: Composition-based stats.
Identities = 40/201 (20%), Positives = 73/201 (36%), Gaps = 18/201 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH-----LETNFTLKSEWATHKFADCK------ 173
P P+N+ IVNE + EW RET K + C
Sbjct 322 VPSGPRNVISIVNE-TSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFV 380
Query 174 AKRDTPTSCTVDYSTVY-FVNIEVWVEAENALGKVTS-DHINFDPVYKVKPNPPHNLSVI 231
++ T C V S+++ ++A N + + + P + ++
Sbjct 381 PRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIM 440
Query 232 NSEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + + L+W P + IIL Y I+Y K+ ++ S ++ + L+
Sbjct 441 HQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEH---NEFNSSMARSQTNTARIDGLR 497
Query 291 PFTEYVFRIRCMKEDGKGYWS 311
P YV ++R G G +S
Sbjct 498 PGMVYVVQVRARTVAGYGKFS 518
Score = 108 bits (268), Expect = 2e-22, Method: Composition-based stats.
Identities = 54/306 (18%), Positives = 100/306 (33%), Gaps = 34/306 (11%)
Query 424 THPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL-----------SDKAPCITDWQQ 472
++ + + + +EW PRE+ + + + ++ S + +
Sbjct 323 PSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPR 382
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVRT 527
+ G +L Y + + SP S+ QA PS P +
Sbjct 383 QLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQ 442
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT-EYTLSSLTSDT 586
L W Q + NG I +Y I Y NE ++ S T + L
Sbjct 443 VSATMRSITLSWPQ--PEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGM 500
Query 587 LYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGE--------IEAIVVPVCLAFLLTTLLGV 637
+Y+V++ A T G GK + F T + + A + F+++ +
Sbjct 501 VYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAIS 560
Query 638 LFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSD----GNFTDVSV 693
+ C KR K+ + + + SP + + + DVS
Sbjct 561 IVCSRKRAYSKEAAYSD--KLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSF 618
Query 694 VEIEAN 699
V+IE
Sbjct 619 VKIEEV 624
Score = 79.9 bits (195), Expect = 8e-14, Method: Composition-based stats.
Identities = 54/311 (17%), Positives = 90/311 (29%), Gaps = 50/311 (16%)
Query 127 EKPKNLSCIVNEGKKMR----CEWDGGRETHLETN------FTLKSEWATHKFADCKAKR 176
+ P L C +G+ M C G E T K+ + C +
Sbjct 233 DVPIKLYCN-GDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNS 291
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
+P+ + T +FDP + P + S
Sbjct 292 RSPSEAS-PICTCRTGYYR----------------ADFDPPEVACTSVPSGPRNVISIVN 334
Query 237 SSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWS--------QIPPEDTASTRSSFTVQ 287
+ + L W P + YNI + A S + P T ++
Sbjct 335 ETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSIS 394
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSE-EASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
L T Y F I+ + + T + PS P I + R+
Sbjct 395 SLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVP-----IMHQVSATMRS 449
Query 347 VQLVWKTLPPFEANGKILDYEVTLT-----RWKSHLQNYTVNATKLTVNLTNDRYLATLT 401
+ L W P + NG ILDYE+ + S + N ++ Y+ +
Sbjct 450 ITLSW--PQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVR 507
Query 402 VRNLVGKSDAA 412
R + G +
Sbjct 508 ARTVAGYGKFS 518
Score = 61.4 bits (147), Expect = 4e-08, Method: Composition-based stats.
Identities = 27/225 (12%), Positives = 55/225 (24%), Gaps = 30/225 (13%)
Query 310 WSDWSEEASGIT-YEDRPSKAPSFWYKIDPS------HTQGYRTVQLVWKTLPPFEANGK 362
S+ S + T Y P PS ++ L W
Sbjct 294 PSEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDD 353
Query 363 ILDYEV----------TLTRWKSHLQNYTVNA------TKLTVNLTNDRYLATLTVRNLV 406
+ Y + + +R +++ ++ + Y + N V
Sbjct 354 VT-YNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGV 412
Query 407 G-KSDAA----VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
KS + I + + + + + W E IL++ +
Sbjct 413 SSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSW-PQPEQPNGIILDYEIRY 471
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ + T L Y++ V G G
Sbjct 472 YEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGK 516
>sp|E9Q0N2|PTPRH_MOUSE Receptor-type tyrosine-protein phosphatase
H OS=Mus musculus OX=10090 GN=Ptprh PE=1 SV=1
Length=971
Score = 119 bits (298), Expect = 4e-26, Method: Composition-based stats.
Identities = 83/428 (19%), Positives = 140/428 (33%), Gaps = 51/428 (12%)
Query 172 CKAKRDTPTSCTVD-YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
C R TS TVD ++ +WVE G +S I PV PNP NL V
Sbjct 22 CSVVRAAGTSVTVDRHAPASSYEFSMWVE---KDGVSSSPQI---PVTTAAPNPVRNLRV 75
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+S + L+W P S+ L Y Q T E +T +S TV L
Sbjct 76 EGQNNIS--ISLSWEPPDQSSLQGLTYWTQCSRHGGQT------ETRNTTDTSVTVDGLD 127
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR--PSKAPSFWYKIDPSHTQGYRTVQ 348
P + Y S W E+ + + S AP+ + ++
Sbjct 128 PGSSYE-------------CSVWVEKDGLYSKNETLNTSTAPNPVRNLRVEGQNNI-SIS 173
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK 408
L W+ PP + + + L Y +R + T +TV+ + +V
Sbjct 174 LSWE--PPDQPSLQGLTYWAQCSRHGGQTETRNTADTSVTVDGLDPGSSYECSVWVEKDG 231
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDN-MLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
+ T+ A +PV +L+ ++N + + W P + + + W S
Sbjct 232 VYSTNETLNTST--APNPVRNLRVEGQNNISISLSWEPPDQPSLQGLTYWAQCSRHGGQ- 288
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
+ T + L Y +V + G + + P+ +R
Sbjct 289 ---TETRNTTDTSITVDGLDPGSSYECSVWV---EKDGVYSTNETLSNTTAPNPVRNLRV 342
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV-DSSHTEYTLSSLTSDT 586
K L W+ G I++ + +++ T T+ L
Sbjct 343 KSQNNFSISLSWEPPDQPSLQG-----LIYWAQCSRHGGQTETRNTTDTSVTVDGLDPGF 397
Query 587 LYM--VRM 592
LY V +
Sbjct 398 LYKCSVWV 405
Score = 117 bits (293), Expect = 1e-25, Method: Composition-based stats.
Identities = 79/475 (17%), Positives = 150/475 (32%), Gaps = 51/475 (11%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P +NL + W+ ++ L+ + + + T TS TVD
Sbjct 67 PNPVRNLRVEGQNNISISLSWEPPDQSSLQ--GLTYWTQCSRHGGQTETRNTTDTSVTVD 124
Query 186 -YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
VWVE + K + + + PNP NL V +S + L+W
Sbjct 125 GLDPGSSYECSVWVEKDGLYSKNETLNTS------TAPNPVRNLRVEGQNNIS--ISLSW 176
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
P S+ L Y Q T E + +S TV L P + Y
Sbjct 177 EPPDQPSLQGLTYWAQCSRHGGQT------ETRNTADTSVTVDGLDPGSSYE-------- 222
Query 305 DGKGYWSDWSEEASGITYEDR--PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
S W E+ + + S AP+ + ++ L W+ PP + + +
Sbjct 223 -----CSVWVEKDGVYSTNETLNTSTAPNPVRNLRVEGQNNI-SISLSWE--PPDQPSLQ 274
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
L Y +R + T +TV+ + +V + T+
Sbjct 275 GLTYWAQCSRHGGQTETRNTTDTSITVDGLDPGSSYECSVWVEKDGVYSTNETLSNTT-- 332
Query 423 ATHPVMDLKAFPKDN-MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
A +PV +L+ ++N + + W P + + ++ W S + T +
Sbjct 333 APNPVRNLRVKSQNNFSISLSWEPPDQPSLQGLIYWAQCSRHGGQ----TETRNTTDTSV 388
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKA-YLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
L Y +V + E++ + + + +R + L W+
Sbjct 389 TVDGLDPGFLYKCSVWVEKDGVYSTNETLNTSTVPISASNPVRNLRVEGQNNFSISLSWE 448
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNV-DSSHTEYTLSSLTSDTLYM--VRM 592
G ++ + +++ T T+ L + Y V +
Sbjct 449 PPDQSSLQG-----LTYWAQCSRHGGQTETRNTADTSVTVDGLDPGSSYECSVWV 498
Score = 108 bits (269), Expect = 1e-22, Method: Composition-based stats.
Identities = 84/481 (17%), Positives = 144/481 (30%), Gaps = 52/481 (11%)
Query 119 TIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDT 178
T+ + P +NL + W+ + L+ + + +
Sbjct 149 TLNTSTAPNPVRNLRVEGQNNISISLSWEPPDQPSLQ--GLTYWAQCSRHGGQTETRNTA 206
Query 179 PTSCTVD-YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
TS TVD VWVE + + + + PNP NL V +S
Sbjct 207 DTSVTVDGLDPGSSYECSVWVEKDGVYSTNETLNTS------TAPNPVRNLRVEGQNNIS 260
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ L+W P S+ L Y Q T E +T +S TV L P + Y
Sbjct 261 --ISLSWEPPDQPSLQGLTYWAQCSRHGGQT------ETRNTTDTSITVDGLDPGSSYE- 311
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPS--KAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
S W E+ + + S AP+ + + ++ L W+
Sbjct 312 ------------CSVWVEKDGVYSTNETLSNTTAPNPVRNLRVKSQNNF-SISLSWEPPD 358
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLA--TLTVRNLVGKSDAAV 413
G I Y +R + T +TV+ + +L ++ V S
Sbjct 359 QPSLQGLI--YWAQCSRHGGQTETRNTTDTSVTVDGLDPGFLYKCSVWVEKDGVYSTNET 416
Query 414 LTIPACDFQATHPVMDLKAFPKDN-MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQ 472
L A++PV +L+ ++N + + W P +S + + W S +
Sbjct 417 LNTSTVPISASNPVRNLRVEGQNNFSISLSWEPPDQSSLQGLTYWAQCSRHGGQ----TE 472
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGK 532
T + L Y +V + E++ A T G
Sbjct 473 TRNTADTSVTVDGLDPGSSYECSVWVEKDGVYSTNETLNTSTVPAAV--NITSCISTSGG 530
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+L W Y F + + N T+S L Y +
Sbjct 531 YGVLLTWSCPSG--------GYESFEVKVGRKWRSENGSLCGKGVTVSDLEPAQSYTATV 582
Query 593 A 593
Sbjct 583 T 583
Score = 84.1 bits (206), Expect = 4e-15, Method: Composition-based stats.
Identities = 73/402 (18%), Positives = 130/402 (32%), Gaps = 37/402 (9%)
Query 119 TIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDT 178
T+ + P +NL + W+ + L+ + + + T
Sbjct 238 TLNTSTAPNPVRNLRVEGQNNISISLSWEPPDQPSLQ--GLTYWAQCSRHGGQTETRNTT 295
Query 179 PTSCTVD-YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
TS TVD VWVE G +++ + PNP NL V + S
Sbjct 296 DTSITVDGLDPGSSYECSVWVE---KDGVYSTNETLSNTTA---PNPVRNLRVKSQNNFS 349
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ L+W P S+ L Y Q T E +T +S TV L P Y
Sbjct 350 --ISLSWEPPDQPSLQGLIYWAQCSRHGGQT------ETRNTTDTSVTVDGLDPGFLYKC 401
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
+ K+ G +S E + T P A + + + ++ L W+
Sbjct 402 SVWVEKD---GVYSTN-ETLNTST---VPISASNPVRNLRVEGQNNF-SISLSWEPPDQS 453
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
G L Y +R + T +TV+ + +V + T+
Sbjct 454 SLQG--LTYWAQCSRHGGQTETRNTADTSVTVDGLDPGSSYECSVWVEKDGVYSTNETLN 511
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT- 476
A + + + + W+ P + + ++ W+ E+G+
Sbjct 512 TSTVPAAVNITSCISTSGGYGVLLTWSCPSGGYESFEVK---------VGRKWRSENGSL 562
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ +L ++ Y TVT V+ D S + + A
Sbjct 563 CGKGVTVSDLEPAQSYTATVTTVFKDLKAQSLSTTCHTESAA 604
>sp|Q5XKE0|MYPC2_MOUSE Myosin-binding protein C, fast-type OS=Mus
musculus OX=10090 GN=Mybpc2 PE=1 SV=1
Length=1136
Score = 119 bits (298), Expect = 5e-26, Method: Composition-based stats.
Identities = 84/478 (18%), Positives = 141/478 (29%), Gaps = 54/478 (11%)
Query 145 EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
W G E T + + DC + + + + V N +
Sbjct 572 TWLRGDEVFTAT----EGRTHIEQRPDCSSFVIESAERSDEGR------YTIKVT--NPV 619
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRT 263
G+ D + P+PP + V + E +I L W P + Y ++ +
Sbjct 620 GE---DVASIFLRVVDVPDPPEAVRVTSVGEDWAI--LVWEPPKYDGGQPVTGYLMERKK 674
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
K + W +I E T + + Y R+ + G S ++ I
Sbjct 675 KGSQRWMKINFEVFTDTT--YESTKMIEGVLYEMRVFAVNAIGVSQPSMNTKPFMPI--- 729
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL----TRWKSHLQN 379
P+ AP D + T L W+ P G I Y V +
Sbjct 730 -APTSAPQHLTVEDVTDTTTT----LKWRP-PDRIGAGGIDGYLVEYCLEGSEEWVPANK 783
Query 380 YTVNATKLTV--NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV---------- 427
V TV T R L + N+ G+S+ A L P +
Sbjct 784 EPVERCGFTVKDLPTGARILFRVVGVNIAGRSEPATLLQPVTIREIVEQPKIRLPRHLRQ 843
Query 428 MDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
++ + L + + + L + + R R +
Sbjct 844 TYIRKVGEALNLVIPFQGKPRPQVVWTKGGAPLDTSRVNVRTSDFDTVFFVRQAARSD-- 901
Query 488 ESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
S Y ++V +I+ + + V K+V A++EW P D
Sbjct 902 -SGEYELSVQIENMK---DTATIRIRVVEKA-GPAENVMVKEVWGTNALVEWQP-PKDDG 955
Query 548 NGFIRNYTIFYRTIIG-NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
N I Y + V + HT T+S L Y R+ + G D P
Sbjct 956 NSEITGYFVQKADKKTMEWFNVYEHNRHTSCTVSDLIVGNEYYFRIFSENICGLSDSP 1013
Score = 104 bits (259), Expect = 2e-21, Method: Composition-based stats.
Identities = 60/417 (14%), Positives = 132/417 (32%), Gaps = 21/417 (5%)
Query 109 GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR-ETHLE-TNFTLKSEWAT 166
+ ++V I + P+ P+ + W+ + + T + ++ +
Sbjct 617 NPVGEDVASIFLRVVDVPDPPEAVRVTSVGEDWAILVWEPPKYDGGQPVTGYLMERKKKG 676
Query 167 HKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH 226
+ + + V E+ V A NA+G + + P
Sbjct 677 SQRWMKINFEVFTDTTYESTKMIEGVLYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSAPQ 736
Query 227 NLSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
+L+V + + ++ LK W P I + I Y ++Y + + W +P R FT
Sbjct 737 HLTVEDVTDTTTTLK--WRPPDRIGAGGIDGYLVEYCLEGSEEW--VPANKEPVERCGFT 792
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSFWYKIDPSHTQGY 344
V+DL +FR+ + G+ + + + ++P + P +
Sbjct 793 VKDLPTGARILFRVVGVNIAGRSEPATLLQPVTIREIVEQPKIRLPRHLRQTYIRKVGEA 852
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV----NLTNDRYLATL 400
+ + ++ P + + +R ++ T V + Y ++
Sbjct 853 LNLVIPFQGKPRPQVVWTKGGAPLDTSRVNVRTSDF---DTVFFVRQAARSDSGEYELSV 909
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
+ N+ D A + I + + +K N L VEW P++ I + V
Sbjct 910 QIENMK---DTATIRIRVVEKAGPAENVMVKEVWGTNAL-VEWQPPKDDGNSEITGYFVQ 965
Query 461 SDKAPCITDWQQEDG-TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+W H + +L Y + G + +
Sbjct 966 KADK-KTMEWFNVYEHNRHTSCTVSDLIVGNEYYFRIFSENICGLSDSPGVSKNTAR 1021
>sp|Q90688|MYPC3_CHICK Myosin-binding protein C, cardiac-type
OS=Gallus gallus OX=9031 GN=MYBPC3 PE=1 SV=3
Length=1272
Score = 119 bits (297), Expect = 6e-26, Method: Composition-based stats.
Identities = 77/430 (18%), Positives = 135/430 (31%), Gaps = 44/430 (10%)
Query 197 WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIIL 255
V +N +G+ D + P+PP + N E + W P+ +L
Sbjct 748 RVIVKNPVGE---DKADITVKVIDVPDPPEAPKISNIGE--DYCTVQWQPPTYDGGQPVL 802
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y ++ + K + W ++ + ++ + + Y RI + G S S+
Sbjct 803 GYILERKKKKSYRWMRLNFDLL--KELTYEAKRMIEGVVYEMRIYAVNSIGMSRPSPASQ 860
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT---- 371
I P P+ + D S T TV L W+ P G + Y V
Sbjct 861 PFMPI----APPSEPTHFTVEDVSDT----TVALKWRP-PERIGAGGLDGYIVEYCKDGS 911
Query 372 -RWKSHLQNYTVNATKLTVNL-TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV-- 427
W L T + L +L T D+ + NL G+S AA++ P +
Sbjct 912 AEWTPALPGLTERTSALIKDLVTGDKLYFRVKAINLAGESGAAIIKEPVTVQEIMQRPKI 971
Query 428 --------MDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+K + + + + ++ + L K I +
Sbjct 972 CVPRHLRQTLVKKVGETINIMIPFQGKPRPKISWMKDGQTLDSKDVGI---RNSSTDTIL 1028
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ-APPSKGPTVRTKKVGKNEAVLE 538
+ L S Y +T+ +++ ++ P ++ V LE
Sbjct 1029 FIRKAELHHSGAYEVTLQIENMT-----DTVAITIQIIDKPGPPQNIKLADVWGFNVALE 1083
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD-SSHTEYTLSSLTSDTLYMVRMAAYTD 597
W P D N I YT+ E D T +S L Y R+ +
Sbjct 1084 WTP-PQDDGNAQILGYTVQKADKKTMEWYTVYDHYRRTNCVVSDLIMGNEYFFRVFSENL 1142
Query 598 EGGKDGPEFT 607
G + T
Sbjct 1143 CGLSETAATT 1152
Score = 103 bits (255), Expect = 6e-21, Method: Composition-based stats.
Identities = 71/466 (15%), Positives = 147/466 (32%), Gaps = 43/466 (9%)
Query 107 TFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN--FTLKSEW 164
G+ + ++ I PPE PK +S I + +W + + L+ +
Sbjct 754 PVGEDKADITVKVIDVPDPPEAPK-ISNIGED--YCTVQWQPPTYDGGQPVLGYILERKK 810
Query 165 ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNP 224
+ V E+ + A N++G + + P+
Sbjct 811 KKSYRWMRLNFDLLKELTYEAKRMIEGVVYEMRIYAVNSIGMSRPSPASQPFMPIAPPSE 870
Query 225 PHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P + +V + + + + L W P I + + Y ++Y ++ W+ P T R+S
Sbjct 871 PTHFTVEDVSD--TTVALKWRPPERIGAGGLDGYIVEYCKDGSAEWTPALPGLTE--RTS 926
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK-APSFWYKIDPSHTQ 342
++DL + FR++ + G+ + E + RP P +
Sbjct 927 ALIKDLVTGDKLYFRVKAINLAGESGAAIIKEPVTVQEIMQRPKICVPRHLRQTLVKKVG 986
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL----------T 392
+ + ++ P +++ + L + V + +
Sbjct 987 ETINIMIPFQGKPRP---------KISWMKDGQTLDSKDVGIRNSSTDTILFIRKAELHH 1037
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
+ Y TL + N+ +D +TI D + L N + +EWT P++
Sbjct 1038 SGAYEVTLQIENM---TDTVAITIQIIDKPGPPQNIKLADVWGFN-VALEWTPPQDDGNA 1093
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
IL + V + + D + +L Y V + G E+
Sbjct 1094 QILGYTVQKADKKTMEWYTVYDHYRRTNCVVSDLIMGNEYFFRV--FSENLCGLSETAAT 1151
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLP----VDVQNGFIRNY 554
P+ T + ++ + P V I Y
Sbjct 1152 TKN---PAYIQKTGTTYKPPSYKEHDFSEPPKFTHPLVNRSVIAGY 1194
Score = 94.2 bits (232), Expect = 4e-18, Method: Composition-based stats.
Identities = 46/213 (22%), Positives = 77/213 (36%), Gaps = 11/213 (5%)
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
D + + V+N VG+ D A +T+ D + +D V+W P +
Sbjct 742 EDEGVYRVIVKNPVGE-DKADITVKVIDVPDPPEAPKISNIGEDYCT-VQWQPPTYDGGQ 799
Query 453 YILEWCVLSDKAPCITDWQQE--DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
+L + +L K W + D TY + E Y + + V + G P
Sbjct 800 PVLGY-ILERKKKKSYRWMRLNFDLLKELTYEAKRMIEGVVYEMRIYAVNSIGMSRPSPA 858
Query 511 -KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAV 568
+ ++ APPS+ + V L+W P + G + Y + Y + T
Sbjct 859 SQPFMPIAPPSEPTHFTVEDVSDTTVALKWRP-PERIGAGGLDGYIVEYCKDGSAEWTPA 917
Query 569 NVDSSH-TEYTLSSL-TSDTLYMVRMAAYTDEG 599
+ T + L T D LY R+ A G
Sbjct 918 LPGLTERTSALIKDLVTGDKLY-FRVKAINLAG 949
>sp|P28828|PTPRM_MOUSE Receptor-type tyrosine-protein phosphatase
mu OS=Mus musculus OX=10090 GN=Ptprm PE=1 SV=2
Length=1452
Score = 119 bits (297), Expect = 7e-26, Method: Composition-based stats.
Identities = 61/395 (15%), Positives = 122/395 (31%), Gaps = 35/395 (9%)
Query 194 IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI 253
+ E +G + V K P P + + ++L N
Sbjct 258 YRCMICTEGGVGISN----YAELVVKEPPVPIAPPQLASVGATYLWIQLN-ANSINGDGP 312
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
I+ ++Y T + +W+ P D +S+ + L P TEY + + G+G
Sbjct 313 IVAREVEYCTA-SGSWNDRQPVD----STSYKIGHLDPDTEYEISVL-LTRPGEGGTGSP 366
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL----------PPFEANGKI 363
T P + P ++ R + + W+ G
Sbjct 367 GPALRTRTKCADPMRGPRKLEVVEV----KSRQITIRWEPFGYNVTRCHSYNLTVHYGYQ 422
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC-DFQ 422
+ + + S + + +T L + N G+ ++ LT+ D
Sbjct 423 VGGQEQVREEVSWDTDNSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELTVQTDEDLP 482
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKK---YILEWCVLSDKAPCITDWQQEDGTVHR 479
P ++ + ++++W P ++ Y + + +S P I D + G V +
Sbjct 483 GAVPTESIQGSAFEEKIFLQWREPTQTYGVITLYEITYKAVSSFDPEI-DLSNQSGRVSK 541
Query 480 T-----YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE 534
+L L Y T+ A G G P + + K + PS + + +
Sbjct 542 LGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKISAPSMPAYEFETPLNQTD 601
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
+ P + + Y I T
Sbjct 602 NTVTVMLKPAQSRGAPVSVYQIVVEEERPRRTKKT 636
Score = 87.2 bits (214), Expect = 4e-16, Method: Composition-based stats.
Identities = 43/295 (15%), Positives = 86/295 (29%), Gaps = 27/295 (9%)
Query 350 VWKTLPPFEANG--KILDYEVTLTRWKSHLQN-YTVNATKLTVNLTNDRYLATLTV---- 402
+W L NG I+ EV + V++T + + ++V
Sbjct 298 LWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLTR 357
Query 403 --RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK------YI 454
G A+ T C P K + + W +V + +
Sbjct 358 PGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTV 417
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+ + + + H + NL+ + + + +G + +
Sbjct 418 HYGYQVGGQEQVREEVSWDTDNSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELTVQT 477
Query 515 KQAPPSKGPTVRTK-KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD-- 571
+ P PT + + + L+W + G I Y I Y+ + + +++
Sbjct 478 DEDLPGAVPTESIQGSAFEEKIFLQWRE--PTQTYGVITLYEITYKAVSSFDPEIDLSNQ 535
Query 572 -------SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE 619
+ T + L T Y + A T +G FTT A
Sbjct 536 SGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKISAPSMPA 590
Score = 77.6 bits (189), Expect = 4e-13, Method: Composition-based stats.
Identities = 50/250 (20%), Positives = 90/250 (36%), Gaps = 23/250 (9%)
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
T +Y + VG S+ A L + P + A LW++
Sbjct 250 TTKRDAGKYRCMICTEGGVGISNYAELVVKEPPVPIAPPQL---ASVGATYLWIQLNANS 306
Query 448 ----ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV--TPVYA 501
+ +E+C S W +Y G+L Y I+V T
Sbjct 307 INGDGPIVAREVEYCTASGS------WNDRQPVDSTSYKIGHLDPDTEYEISVLLTRPGE 360
Query 502 DGPGSPES-IKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQ-----LPVDVQNGFIR-N 553
G GSP ++ K A P +GP + +V + + W+ N +
Sbjct 361 GGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTVHYG 420
Query 554 YTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKF 613
Y + + + E + + D+SH ++T+++L+ T V++ EG K+ E T T +
Sbjct 421 YQVGGQEQVREEVSWDTDNSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELTVQTDED 480
Query 614 AQGEIEAIVV 623
G + +
Sbjct 481 LPGAVPTESI 490
>sp|Q14896|MYPC3_HUMAN Myosin-binding protein C, cardiac-type
OS=Homo sapiens OX=9606 GN=MYBPC3 PE=1 SV=4
Length=1274
Score = 118 bits (296), Expect = 8e-26, Method: Composition-based stats.
Identities = 72/460 (16%), Positives = 140/460 (30%), Gaps = 29/460 (6%)
Query 107 TFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN--FTLKSEW 164
G+ + N+ I P PK +W+ + + L+ +
Sbjct 756 PVGEDQVNLTVKVIDVPDAPAAPKI---SNVGEDSCTVQWEPPAYDGGQPILGYILERKK 812
Query 165 ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNP 224
+ V E+ V A NA+G + + P+
Sbjct 813 KKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSE 872
Query 225 PHNLSVINSEELSSILKLTWTNPSI-KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P +L+V + + + + L W P + + Y+++Y + S W + + +S
Sbjct 873 PTHLAVEDVSD--TTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEW--VAALQGLTEHTS 928
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSFWYKIDPSHTQ 342
V+DL +FR+R G G +E + RP + P +
Sbjct 929 ILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVG 988
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQNYTVNATKLTVNLTNDRYLATLT 401
+ + ++ P + + + T+ + + + Y T+
Sbjct 989 EPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVR 1048
Query 402 VRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM-LWVEWTTPRESVKKYILEWCVL 460
+ N+ D A L + D P DL+ + + +EW P++ + + V
Sbjct 1049 IENM---EDKATLVLQVVD--KPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103
Query 461 SDKAPCITDWQQEDGTVHRTY-LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
+W RT+ + L Y V G A K+
Sbjct 1104 KADK-KTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRA---ATTKEPVF 1159
Query 520 SKGPTVRTKKVGKNEAVLEWDQLP----VDVQNGFIRNYT 555
P + N L++ + P V I YT
Sbjct 1160 IPRPGIT--YEPPNYKALDFSEAPSFTQPLVNRSVIAGYT 1197
Score = 109 bits (273), Expect = 4e-23, Method: Composition-based stats.
Identities = 51/228 (22%), Positives = 86/228 (38%), Gaps = 11/228 (5%)
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
D + T+TV+N VG+ D LT+ D + +D+ V+W P +
Sbjct 744 EDEGVYTVTVKNPVGE-DQVNLTVKVIDVPDAPAAPKISNVGEDSCT-VQWEPPAYDGGQ 801
Query 453 YILEWCVLSDKAPCITDWQQE--DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
IL + +L K W + D ++ + E Y + V V A G P
Sbjct 802 PILGY-ILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPA 860
Query 511 -KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
+ ++ PPS+ + + V L+W P V G + Y++ Y +E
Sbjct 861 SQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRP-PERVGAGGLDGYSVEYCPEGCSEWVAA 919
Query 570 VD--SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ 615
+ + HT + L + + R+ A+ G G T T P Q
Sbjct 920 LQGLTEHTSILVKDLPTGARLLFRVRAHNMAG--PGAPVTTTEPVTVQ 965
>sp|Q14324|MYPC2_HUMAN Myosin-binding protein C, fast-type OS=Homo
sapiens OX=9606 GN=MYBPC2 PE=1 SV=2
Length=1141
Score = 118 bits (296), Expect = 8e-26, Method: Composition-based stats.
Identities = 94/584 (16%), Positives = 165/584 (28%), Gaps = 82/584 (14%)
Query 67 WKTNHFTIPKEQYTIINRTAS--SVTFTDIASLNIQLTCNILTFG--QLEQNVYGITIIS 122
W N + + I+ + D+ + + L + + I
Sbjct 471 WYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKV 530
Query 123 GLPP--EKPKN-LSCIVNEGKKMRC---------------------EWDGGRETHLETNF 158
P E PK L C + W G E T
Sbjct 531 EYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTT-- 588
Query 159 TLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVY 218
+ K DC + + + V N +G+ D +
Sbjct 589 --EGRTRIEKRVDCSSFVIESAQREDEGR------YTIKVT--NPVGE---DVASIFLQV 635
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
P+PP + + + E +I L W P + Y ++ + K + W ++ E
Sbjct 636 VDVPDPPEAVRITSVGEDWAI--LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFE-- 691
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
T +++ + Y R+ + G S ++ I P+ P D
Sbjct 692 VFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPI----APTSEPLHLIVED 747
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL----TRWKSHLQNYTVNATKLTV--NL 391
+ T L W+ G I Y V + V TV
Sbjct 748 VTDTTTT----LKWRPPNRI-GAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLP 802
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV----------MDLKAFPKDNMLWV 441
T R L + N+ G+S+ A L P + P ++ + L V
Sbjct 803 TGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVV 862
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
+ + ++ + + D + ++S Y ++V
Sbjct 863 ---PFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENM 919
Query 502 DGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI 561
+I+ + + V K+V A++EW Q P D N I Y +
Sbjct 920 K---DTATIRIRVVEKA-GPPINVMVKEVWGTNALVEW-QAPKDDGNSEIMGYFVQKADK 974
Query 562 IG-NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
V + HT T+S L Y R+ G D P
Sbjct 975 KTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSP 1018
Score = 105 bits (262), Expect = 8e-22, Method: Composition-based stats.
Identities = 58/417 (14%), Positives = 131/417 (31%), Gaps = 21/417 (5%)
Query 109 GQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR-ETHLE-TNFTLKSEWAT 166
+ ++V I + P+ P+ + W+ + T + ++ +
Sbjct 622 NPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKG 681
Query 167 HKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH 226
+ + + + E+ V A NA+G + + P
Sbjct 682 SQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPL 741
Query 227 NLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
+L V + + ++ LK W P I + I Y ++Y + + W E R FT
Sbjct 742 HLIVEDVTDTTTTLK--WRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVE--RCGFT 797
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSFWYKIDPSHTQGY 344
V++L +FR+ + G+ + ++ + + P + P +
Sbjct 798 VKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQ 857
Query 345 RTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN----LTNDRYLATL 400
+ + ++ P + + +R ++ T V + Y ++
Sbjct 858 LNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDF---DTVFFVRQAARSDSGEYELSV 914
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
+ N+ D A + I + +A P+ + VEW P++ I+ + V
Sbjct 915 QIENMK---DTATIRIRVVE-KAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQ 970
Query 461 SDKAPCITDWQQE-DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+W + H + +L Y V G + +
Sbjct 971 KADK-KTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTAR 1026
>sp|Q96MS0|ROBO3_HUMAN Roundabout homolog 3 OS=Homo sapiens OX=9606
GN=ROBO3 PE=1 SV=2
Length=1386
Score = 118 bits (295), Expect = 1e-25, Method: Composition-based stats.
Identities = 84/550 (15%), Positives = 164/550 (30%), Gaps = 75/550 (14%)
Query 30 YISPESPVVQLHSNFTAVCVLKEKCMDYFHVNAN--YIVWKTNHFTIPKEQYTIINRTAS 87
P+ + + C K ++ + P ++++ R
Sbjct 350 VTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQL 409
Query 88 SVTFTDIASLNIQLTCNILTFGQLEQ----NVYGITIISGLPP---EKPKNLSCIVNEGK 140
++T + + G + + G ++ GLPP + P N + ++
Sbjct 410 NITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLD-GLPPVILQGPANQTLVLGSSV 468
Query 141 KMRCE----------------WDGGRETHLET--NFTLKSEWATHKFADCKAKRDTPTSC 182
+ C W G + +T N TL A+ + SC
Sbjct 469 WLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLY-------IANVQEMDMGFYSC 521
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
V S+ W++ G +P P P V +E + + L
Sbjct 522 -VAKSSTGEATWSGWLKMREDWGVSPDPPT--EPSS--PPGAPSQPVV--TEITKNSITL 574
Query 243 TWTNPSIKSVIILKYNIQ-YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
TW + Y I+ + +TW + + TV L+P T Y+F +R
Sbjct 575 TWKPNPQTGAAVTSYVIEAFSPAAGNTWRTVAD---GVQLETHTVSGLQPNTIYLFLVRA 631
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKA-PSFWY----------KIDPSHTQGYRTVQLV 350
+ G S SE T + PS+ W ++ G RT+Q+
Sbjct 632 VGAWGLSEPSPVSEPVR--TQDSSPSRPVEDPWRGQQGLAEVAVRLQEPIVLGPRTLQVS 689
Query 351 WKTLPPFEANGKILDYEVTLTRWKSHLQNYTV--------NATKLTVNLTNDRYLATLTV 402
W P + + + V+ ++T+ +T L + +
Sbjct 690 WTVDGPVQ---LVQGFRVSWRVAGPEGGSWTMLDLQSPSQQSTVLRGLPPGTQIQIKVQA 746
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFP----KDNMLWVEWTTPRESVKKYIL-EW 457
+ G ++ + +A A ++ + V W P S + ++ E+
Sbjct 747 QGQEGLGAESLSVTRSIPEEAPSGPPQGVAVALGGDGNSSITVSWEPPLPSQQNGVITEY 806
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
+ + R+ + L Y V + G G P + +
Sbjct 807 QIWCLGNESRFHLNRSAAGWARSAMLRGLVPGLLYRTLVAAATSAGVGVPSAPVLVQLPS 866
Query 518 PPSKGPTVRT 527
PP P +
Sbjct 867 PPDLEPGLEV 876
Score = 117 bits (292), Expect = 2e-25, Method: Composition-based stats.
Identities = 111/640 (17%), Positives = 197/640 (31%), Gaps = 97/640 (15%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P + VV + T +C +K + W+ +P +Y I R+ S+
Sbjct 264 PVNQVVLADAPVTFLCEVK-------GDPPPRLRWRKEDGELPTGRYEI--RSDHSLWIG 314
Query 93 DIASLNIQ-LTCNILTFGQLEQNVYGITIISGLPP---EKPKNLSCIVNEGKKMRCEWDG 148
+++ + TC + ++ +PP +P++ E +CE G
Sbjct 315 HVSAEDEGTYTCVAENSVGRAEA--SGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKG 372
Query 149 GRETHLE-----TNFTLKSEWATHKFADCKAKRDTPTSCT--VDYSTVYFVNIEVWVEAE 201
+ + L + + T Y+V V V
Sbjct 373 NPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSV--- 429
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
G + + + + PP VI + L L S + L +
Sbjct 430 --AGSILAKALLEIKGASLDGLPP----VILQGPANQTLVL-------GSSVWLPCRVTG 476
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR----------CMKEDGKGYWS 311
+ + W + T+ + T Y+ ++ G+ WS
Sbjct 477 NPQPSVRWKKDGQWLQGDDLQFKTMAN---GTLYIANVQEMDMGFYSCVAKSSTGEATWS 533
Query 312 DW--SEEASGITYE--DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
W E G++ + PS P + + ++ L WK P A + Y
Sbjct 534 GWLKMREDWGVSPDPPTEPSSPPGAPSQPVVTEITKN-SITLTWKPNPQTGA--AVTSYV 590
Query 368 V------TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC-- 419
+ W++ + ++ N YL + G S+ + ++ P
Sbjct 591 IEAFSPAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVRTQ 650
Query 420 DFQATHPVMD----------------LKAFPKDNMLWVEWTT--PRESVKKYILEWCVLS 461
D + PV D L V WT P + V+ + + W V
Sbjct 651 DSSPSRPVEDPWRGQQGLAEVAVRLQEPIVLGPRTLQVSWTVDGPVQLVQGFRVSWRVAG 710
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-SIKAYLKQAPPS 520
+ T + + T LRG L I V +G G+ S+ + + PS
Sbjct 711 PEGGSWTMLDLQSPSQQSTVLRG-LPPGTQIQIKVQAQGQEGLGAESLSVTRSIPEEAPS 769
Query 521 KGP---TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY 577
P V G + + W+ QNG I Y I+ +GNE+ +++ S +
Sbjct 770 GPPQGVAVALGGDGNSSITVSWEPPLPSQQNGVITEYQIW---CLGNESRFHLNRSAAGW 826
Query 578 T----LSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPK 612
L L LY +AA T G G P
Sbjct 827 ARSAMLRGLVPGLLYRTLVAAATSAGVGVPSAPVLVQLPS 866
>sp|P57097|MERTK_RAT Tyrosine-protein kinase Mer OS=Rattus norvegicus
OX=10116 GN=Mertk PE=2 SV=1
Length=994
Score = 117 bits (293), Expect = 2e-25, Method: Composition-based stats.
Identities = 69/426 (16%), Positives = 140/426 (33%), Gaps = 43/426 (10%)
Query 36 PVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTI-----INRTASSVT 90
V+ H + C + + + I W + + ++I S +
Sbjct 97 IVLSEHKSVKFNCSI---NIPNVYQETAGISWWKDGKELLGAHHSITQFYPDEEGVSIIA 153
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGIT-IIS---GLPP--EKPKNLSCIVNEGKKMRC 144
I S+ + + ++ I GLP ++P++++ N + C
Sbjct 154 LFSITSVQRSDNGSYICKMKVNDREVVSDPIYVEVQGLPYFTKQPESVNVTRNTAFNLTC 213
Query 145 EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
+ G E + W + + +P+ TV T EA N
Sbjct 214 QAVGPPEP-------VNIFWVQNSSRVNENPERSPSVLTVAGLTE---TAVFSCEAHNDK 263
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK 264
G S + + KV P+PP + ++NS S + ++W + +IQ +
Sbjct 264 GLTVSKGVQINI--KVIPSPPTEVHILNSTAHS--ILVSWVPGFDGYSPLQNCSIQVKEA 319
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
D + + +T+++ + VQ L+ Y + C E G WS S T E
Sbjct 320 DQLSNGSVMVFNTSASPHLYEVQQLQALANYSVTVSCRNEIG---WSAVSPWILASTTEG 376
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL-----TRWKSHLQN 379
P+ AP I + +++ W P +G+++ Y ++ K +
Sbjct 377 APAVAP---LNITVFLNESSNNLEIRWTKPPIKRQDGELVGYRISHVWESAGTSKELSEE 433
Query 380 YTVNATK--LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA--THPVMDLKAFPK 435
+ N + + V + N + V G + A + + A
Sbjct 434 VSQNGSWAQVPVQMHNATCTVRIAVITKGGIGPFSEPVDVAIPEHSRVDYAPSSTPAPGN 493
Query 436 DNMLWV 441
+ +
Sbjct 494 TESMLI 499
Score = 63.7 bits (153), Expect = 6e-09, Method: Composition-based stats.
Identities = 40/298 (13%), Positives = 86/298 (29%), Gaps = 18/298 (6%)
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATK-LTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
+A G + + S + + LTV + + + N G + + + I
Sbjct 214 QAVGPPEPVNIFWVQNSSRVNENPERSPSVLTVAGLTETAVFSCEAHNDKGLTVSKGVQI 273
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRE---SVKKYILEWCVLSDKAPCITDWQQE 473
+ + + + + V W + ++ ++ +
Sbjct 274 NIKVIPSPPTEVHILN-STAHSILVSWVPGFDGYSPLQNCSIQVKEADQLSNGSVMVFNT 332
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK-AYLKQAPPSKGP-TVRT-KKV 530
+ H Y L Y +TV+ G + A + P+ P +
Sbjct 333 SASPH-LYEVQQLQALANYSVTVSCRNEIGWSAVSPWILASTTEGAPAVAPLNITVFLNE 391
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHT-EYTLSSLT-SDTL 587
N + W + P+ Q+G + Y I G ++ + S + + +
Sbjct 392 SSNNLEIRWTKPPIKRQDGELVGYRISHVWESAGTSKELSEEVSQNGSWAQVPVQMHNAT 451
Query 588 YMVRMAAYTDEGGKDGPE------FTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLF 639
VR+A T G E + +A A + +L G +
Sbjct 452 CTVRIAVITKGGIGPFSEPVDVAIPEHSRVDYAPSSTPAPGNTESMLIILGCFCGFVL 509
>sp|P32018|COEA1_CHICK Collagen alpha-1(XIV) chain OS=Gallus gallus
OX=9031 GN=COL14A1 PE=1 SV=2
Length=1888
Score = 118 bits (294), Expect = 2e-25, Method: Composition-based stats.
Identities = 60/381 (16%), Positives = 126/381 (33%), Gaps = 46/381 (12%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P +L + S+ + +++WT+ + KY + Y ++ + ++ST
Sbjct 354 GAPTDL--VTSDITARGFRVSWTH---SPGKVEKYRVVYYPTRGGQPEEVVVDGSSST-- 406
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI-TYEDRPSKAPSFWYKIDPSHT 341
+++L TEY + + + SE G T P S D SH+
Sbjct 407 -AVLKNLMSLTEYQIAVFAIYSN------AASEGLRGTETTLALPMA--SDLKLYDVSHS 457
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ------NYTVNATKLTVNLTNDR 395
+++ W + Y + L +T+L ++
Sbjct 458 ----SMRAKWNGVAGA------TGYMILYAPLTEGLAADEKEIKIGEASTELELDGLLPN 507
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL 455
T+TV + G+ + LT + P + N + W ++VK Y +
Sbjct 508 TEYTVTVYAMFGEEASDPLTGQETTLPLSPPSNLKFSDVGHNSAKLTWDPASKNVKGYRI 567
Query 456 EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
+ + + T+ +L Y + + +Y +G P + +
Sbjct 568 MYVKTDGTETN-----EVEVGPVSTHTLKSLTALTEYTVAIFSLYDEGQSEPLTGSFTTR 622
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET-AVNVDSSH 574
+ PP + + + + W + I Y + + + G E+ V +
Sbjct 623 KVPP--PQHLEVDEASTDSFRVSWKPT-----SSDIAFYRLAWIPLDGGESEEVVLSGDA 675
Query 575 TEYTLSSLTSDTLYMVRMAAY 595
Y + L +T Y V + A
Sbjct 676 DSYVIEGLLPNTEYEVSLLAV 696
Score = 112 bits (279), Expect = 9e-24, Method: Composition-based stats.
Identities = 81/585 (14%), Positives = 146/585 (25%), Gaps = 85/585 (15%)
Query 69 TNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTC-NILTFGQLEQNVYGITIISGLPPE 127
N ++ + D +N + ++E+ I
Sbjct 295 KNADINELKEIASEPDSTHVYNVADFNFMNSIVEGLTRTVCSRVEEQEKEIKGTIAASLG 354
Query 128 KPKNLSCIVNEGKKMRCEW--DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P +L + R W G+ + + T + D +S V
Sbjct 355 APTDLVTSDITARGFRVSWTHSPGKVEKYRVVY-----YPTRGGQPEEVVVDGSSSTAVL 409
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ + ++ V A + S+ + P +L + + S K W
Sbjct 410 KNLMSLTEYQIAVFAIYS--NAASEGLRGTETTLALPMA-SDLKLYDVSHSSMRAK--W- 463
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
Y I Y + + + L P TEY + M
Sbjct 464 ---NGVAGATGYMILYAPLTEGLAADEKEIKIGEASTELELDGLLPNTEYTVTVYAM--- 517
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
+ + S+ +G P PS D H L W +
Sbjct 518 ---FGEEASDPLTGQ-ETTLPLSPPSNLKFSDVGHNSAK----LTWDPASKN-----VKG 564
Query 366 YEVTLTRWKSHLQN----YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
Y + + N V+ L Y + G+S+ LT
Sbjct 565 YRIMYVKTDGTETNEVEVGPVSTHTLKSLTALTEYTVAIFSLYDEGQSEP--LTGSFTTR 622
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
+ P + V W + Y L W L + +Y
Sbjct 623 KVPPPQHLEVDEASTDSFRVSWKPTSSDIAFYRLAWIPLDGGESE----EVVLSGDADSY 678
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP---------------------- 519
+ L + Y +++ V+ D + + A L
Sbjct 679 VIEGLLPNTEYEVSLLAVFDD--ETESEVVAVLGATIVGTTAIPTTVTTTTTTTATTPKP 736
Query 520 ------SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN--ETAVNVD 571
+ + + + WD + Q + + Y T G+ E A+ V
Sbjct 737 TIAVFRTGVRNLVIDDETTSSLRVVWDISDHNAQ-----QFRVTYLTAKGDRAEEAIMVP 791
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEG-----GKDGPEFTFTTP 611
L L DT Y V + +G G + P
Sbjct 792 GRQNTLLLQPLLPDTEYKVTITPIYADGEGVSVSAPGKTLPLSAP 836
Score = 108 bits (269), Expect = 1e-22, Method: Composition-based stats.
Identities = 73/501 (15%), Positives = 143/501 (29%), Gaps = 70/501 (14%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGR--ETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
LP P NL + WD + T++ P S
Sbjct 533 LPLSPPSNLKFSDVGHNSAKLTWDPASKNVKGYRIMYVKTDGTETNEVE------VGPVS 586
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
S V + + G+ S+ + + P PP +L V E + +
Sbjct 587 THTLKSLTALTEYTVAIFSLYDEGQ--SEPLTGSFTTRKVP-PPQHLEVD--EASTDSFR 641
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
++W S I Y + + D ++ + S+ ++ L P TEY +
Sbjct 642 VSWKP---TSSDIAFYRLAWIPLDGGESEEV---VLSGDADSYVIEGLLPNTEYEVSLLA 695
Query 302 MKEDGKGYWSDWSEEASGI-----------------------TYEDRPSKAPSFWYKIDP 338
+ +D S+ D
Sbjct 696 VFDDE--TESEVVAVLGATIVGTTAIPTTVTTTTTTTATTPKPTIAVFRTGVRNLVIDDE 753
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH--LQNYTVNATKLTVNL--TND 394
+ + ++++VW + N + VT K + V + T+ L
Sbjct 754 TTS----SLRVVWD---ISDHNA--QQFRVTYLTAKGDRAEEAIMVPGRQNTLLLQPLLP 804
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI 454
+T+ + + ++ P + P + N L + W P Y
Sbjct 805 DTEYKVTITPIYADGEGVSVSAPGKTLPLSAPRNLRVSDEWYNRLRISWDAPPSPTMGYR 864
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+ + ++ P + + G T L NL Y + V Y+ G +++
Sbjct 865 IVYKSINVPGPAL---ETFVGDDINTILILNLFSGTEYSVKVFASYSTGF--SDALTGVA 919
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT-IIGNETAVNVDSS 573
K + T +V +W + Y + + + G + VN+
Sbjct 920 KTLY-LGVTNLDTYQVRMTSLCAQW------QLHRHATAYRVVIESLVDGKKQEVNLGGG 972
Query 574 HTEYTLSSLTSDTLYMVRMAA 594
+ L T Y + + A
Sbjct 973 VPRHCFFELMPGTEYKISVHA 993
Score = 69.1 bits (167), Expect = 2e-10, Method: Composition-based stats.
Identities = 52/287 (18%), Positives = 90/287 (31%), Gaps = 27/287 (9%)
Query 230 VINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
++ +E +S L++ W I ++ + Y T + +++ +Q L
Sbjct 748 LVIDDETTSSLRVVWD---ISDHNAQQFRVTYLTAKGDRAEEAIM--VPGRQNTLLLQPL 802
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
P TEY I + DG+G S A G T P AP D + + +++
Sbjct 803 LPDTEYKVTITPIYADGEG----VSVSAPGKTL---PLSAPRNLRVSDEWYNR----LRI 851
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL-TNDRYLATLTVRNLVGK 408
W P +I+ + + T L +NL + Y + G
Sbjct 852 SWDAPPSPTMGYRIVYKSINVPGPALETFVGDDINTILILNLFSGTEYSVKVFASYSTGF 911
Query 409 SDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
SDA V +L + + L +W R + ++ +
Sbjct 912 SDALTGVAKTLYLG----VTNLDTYQVRMTSLCAQWQLHRHATAYRVV----IESLVDGK 963
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
G V R L Y I+V + G SI
Sbjct 964 KQEVNLGGGVPRHCFFE-LMPGTEYKISVHAQLQEIEGPAVSIMETT 1009
Score = 66.0 bits (159), Expect = 1e-09, Method: Composition-based stats.
Identities = 68/449 (15%), Positives = 138/449 (31%), Gaps = 83/449 (18%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP L + ++++W P Y + +Q+ ++TA +
Sbjct 32 PPTRLR--YNVVNPDSVQISWKAP---KGQFSGYKLLVTPSSGGKTNQLILQNTA---TK 83
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYW----------------SDWSEEASGITYEDRPS 327
+Q L P Y +I +D + S + T +P+
Sbjct 84 AIIQGLIPDQNYALQIIAFSDDKESKPAQGQFRIKDIERRKETSKSKVKDPEKTNASKPT 143
Query 328 K--------AP---SFWYKIDPSHTQGY---RTVQLVWKTLPPFEANGKILDYEVTLTRW 373
P +D S + G R V+L + L + + V +
Sbjct 144 PEGNLFTCKTPAIADIVILVDGSWSIGRFNFRLVRLFLENL--------VSAFNVGSEKT 195
Query 374 KSHLQNYTVNA---TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
+ L Y+ + L T D L + G + L + + P
Sbjct 196 RVGLAQYSGDPRIEWHLNAYGTKDAVLDAVRNLPYKGGNTLTGLALTYILENSFKPEAGA 255
Query 431 KAFPKDNMLWVE-------WTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
+ + + P ++++ +E + K I + ++ T++
Sbjct 256 RPGVSKIGILITDGKSQDDVIPPAKNLRDAGIELFAIGVKNADINELKEIASEPDSTHVY 315
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLKQ---------APPSKGP-TVRTKKVGKN 533
N+A+ + + G ++ + +++ A P + T +
Sbjct 316 -NVADFNF-------MNSIVEGLTRTVCSRVEEQEKEIKGTIAASLGAPTDLVTSDITAR 367
Query 534 EAVLEWDQLPVDVQNGFIRNYT-IFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+ W P G + Y ++Y T G V VD S + L +L S T Y + +
Sbjct 368 GFRVSWTHSP-----GKVEKYRVVYYPTRGGQPEEVVVDGSSSTAVLKNLMSLTEYQIAV 422
Query 593 AAYTDEGGKD---GPEFTFTTPKFAQGEI 618
A + G E T P + ++
Sbjct 423 FAIYSNAASEGLRGTETTLALPMASDLKL 451
>sp|Q91736|EPB1B_XENLA Ephrin type-B receptor 1-B (Fragment) OS=Xenopus
laevis OX=8355 GN=ephb1-b PE=1 SV=1
Length=902
Score = 117 bits (292), Expect = 2e-25, Method: Composition-based stats.
Identities = 40/201 (20%), Positives = 73/201 (36%), Gaps = 18/201 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH-----LETNFTLKSEWATHKFADCKAKRDT- 178
P P+N+ IVNE + EW RET K + + C D
Sbjct 240 VPSGPRNVISIVNE-TAITLEWHPPRETGGRDDVNYNIICKKCQSDRRGCSHCDDNVDFV 298
Query 179 PTSCTVDYSTVY------FVNIEVWVEAENALGKVTS-DHINFDPVYKVKPNPPHNLSVI 231
P + + V+ ++A N + + + P ++ ++
Sbjct 299 PRQLGLTDTRVFISNLWVHTPYTFEIQAVNGVTNKSPFPPQHVSVNITTNQAAPSSVPIM 358
Query 232 N-SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + + L+W P + IIL Y I+Y KD + S ++ +++ L+
Sbjct 359 HQVKATMKSITLSWPQPEQPNGIILDYEIRYYEKDH---HEFNSSLARSQTNTASIEGLR 415
Query 291 PFTEYVFRIRCMKEDGKGYWS 311
P YV ++R G G +S
Sbjct 416 PGVVYVVQVRARTVAGYGKFS 436
Score = 116 bits (289), Expect = 4e-25, Method: Composition-based stats.
Identities = 64/345 (19%), Positives = 116/345 (34%), Gaps = 37/345 (11%)
Query 386 KLTVNLTNDRYLATLTV-RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
+ N + + + + RN ++D P + ++ + + + +EW
Sbjct 204 QCPANSRSTSEASPICICRNGYYRADFDTPEAPCTSVPSG--PRNVISIVNETAITLEWH 261
Query 445 TPRESVKKYILEWCV-----LSDKAPCITDWQQED------GTVHRTYLRGNLAESKCYL 493
PRE+ + + + + SD+ C D G NL Y
Sbjct 262 PPRETGGRDDVNYNIICKKCQSDRRGCSHCDDNVDFVPRQLGLTDTRVFISNLWVHTPYT 321
Query 494 ITVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
+ V SP S+ QA PS P + K L W Q + N
Sbjct 322 FEIQAVNGVTNKSPFPPQHVSVNITTNQAAPSSVPIMHQVKATMKSITLSWPQ--PEQPN 379
Query 549 GFIRNYTIFYRTIIGNETAVNVDSSHT-EYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEF 606
G I +Y I Y +E ++ S T ++ L +Y+V++ A T G GK +
Sbjct 380 GIILDYEIRYYEKDHHEFNSSLARSQTNTASIEGLRPGVVYVVQVRARTVAGYGKFSSKM 439
Query 607 TFTTPKFAQGE--------IEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDP 658
F T + + A + F+++ + + C KR K+ ++ +
Sbjct 440 CFQTLTEEDYKSELREQLPLIAGSAAAGVVFIVSLVAISIVCSRKRTYSKEAVYSD--KL 497
Query 659 SKSHIAQWSPHTPPRHNFNSKDQMYSD----GNFTDVSVVEIEAN 699
+ SP + + + DVS V+IE
Sbjct 498 QHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEV 542
Score = 63.7 bits (153), Expect = 6e-09, Method: Composition-based stats.
Identities = 26/210 (12%), Positives = 54/210 (26%), Gaps = 25/210 (12%)
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY 380
T E + PS + + L W + +Y + + +S +
Sbjct 232 TPEAPCTSVPS--GPRNVISIVNETAITLEWHPPRETGGRDDV-NYNIICKKCQSDRRGC 288
Query 381 TV--------------NATKLTV--NLTNDRYLATLTVRNLV-GKSDAA----VLTIPAC 419
+ T++ + + Y + N V KS + I
Sbjct 289 SHCDDNVDFVPRQLGLTDTRVFISNLWVHTPYTFEIQAVNGVTNKSPFPPQHVSVNITTN 348
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ + + + + W E IL++ + + +
Sbjct 349 QAAPSSVPIMHQVKATMKSITLSW-PQPEQPNGIILDYEIRYYEKDHHEFNSSLARSQTN 407
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPES 509
T L Y++ V G G S
Sbjct 408 TASIEGLRPGVVYVVQVRARTVAGYGKFSS 437
>sp|Q91845|EPA4A_XENLA Ephrin type-A receptor 4-A OS=Xenopus laevis
OX=8355 GN=epha4-a PE=2 SV=1
Length=986
Score = 117 bits (292), Expect = 2e-25, Method: Composition-based stats.
Identities = 47/240 (20%), Positives = 80/240 (33%), Gaps = 22/240 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHKFADC---------- 172
PP P+NL VNE + EW + + + ++ L + C
Sbjct 328 PPSAPQNLISNVNE-TSVNLEWSPPQNSGGRPDVSYNLVCKRCGSDLTRCRPCGSGVHYS 386
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVI 231
+ T+ N V + N + K P ++ I
Sbjct 387 PQQNGLKTTKVSITDLQAHTNYTFEVWSINGVSKQNPGQDQAVSVTVTTNQAAPSTVTQI 446
Query 232 NSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
++++ + LTW P + +IL+Y ++Y KD ++ +T S ++ L
Sbjct 447 QPKDITRHSVSLTWPEPERPNGVILEYEVKYYEKD---QNERTYRIVKTTSRSADIKGLN 503
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
P T YVF +R G G +S E T PS ++ LV
Sbjct 504 PLTAYVFHVRARTAAGYGEFSGPFEF----TTNTVPSPMIGEGASPTVLLVSVAGSIVLV 559
Score = 111 bits (278), Expect = 8e-24, Method: Composition-based stats.
Identities = 47/246 (19%), Positives = 86/246 (35%), Gaps = 22/246 (9%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV--------LSDKAPCITDWQ--- 471
+L + + + +EW+ P+ S + + + + L+ PC +
Sbjct 328 PPSAPQNLISNVNETSVNLEWSPPQNSGGRPDVSYNLVCKRCGSDLTRCRPCGSGVHYSP 387
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVR 526
Q++G +L Y V + +P S+ QA PS ++
Sbjct 388 QQNGLKTTKVSITDLQAHTNYTFEVWSINGVSKQNPGQDQAVSVTVTTNQAAPSTVTQIQ 447
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSD 585
K + ++ L W + + NG I Y + Y NE T V ++ + L
Sbjct 448 PKDITRHSVSLTWPE--PERPNGVILEYEVKYYEKDQNERTYRIVKTTSRSADIKGLNPL 505
Query 586 TLYMVRMAAYTDEGGKD--GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNK 643
T Y+ + A T G + GP F FTT I P L + + ++
Sbjct 506 TAYVFHVRARTAAGYGEFSGP-FEFTTNTVPSPMIGEGASPTVLLVSVAGSIVLVVILIA 564
Query 644 RDLIKK 649
+I +
Sbjct 565 AFVISR 570
Score = 91.1 bits (224), Expect = 2e-17, Method: Composition-based stats.
Identities = 46/252 (18%), Positives = 79/252 (31%), Gaps = 36/252 (14%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNI----------QYRT 263
DP PP + S + + L W+ P + YN+ + R
Sbjct 319 DPASMPCTRPPSAPQNLISNVNETSVNLEWSPPQNSGGRPDVSYNLVCKRCGSDLTRCRP 378
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK---GYWSDWSEEASGI 320
+ P+ + ++ DL+ T Y F + + K G S +
Sbjct 379 CGSGV--HYSPQQNGLKTTKVSITDLQAHTNYTFEVWSINGVSKQNPGQDQAVS--VTVT 434
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY 380
T + PS +I P +V L W P NG IL+YEV + + Y
Sbjct 435 TNQAAPST----VTQIQPKD-ITRHSVSLTW--PEPERPNGVILEYEVKYYEKDQNERTY 487
Query 381 -TVNATKLTVNL----TNDRYLATLTVRNLV------GKSDAAVLTIPACDFQATHPVMD 429
V T + ++ Y+ + R G + T+P+
Sbjct 488 RIVKTTSRSADIKGLNPLTAYVFHVRARTAAGYGEFSGPFEFTTNTVPSPMIGEGASPTV 547
Query 430 LKAFPKDNMLWV 441
L +++ V
Sbjct 548 LLVSVAGSIVLV 559
Score = 66.0 bits (159), Expect = 1e-09, Method: Composition-based stats.
Identities = 46/243 (19%), Positives = 73/243 (30%), Gaps = 38/243 (16%)
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL------ 377
RP AP + +V L W P + Y + R S L
Sbjct 326 TRPPSAPQ-----NLISNVNETSVNLEWSP-PQNSGGRPDVSYNLVCKRCGSDLTRCRPC 379
Query 378 --------QNYTVNATKLTVNLTN--DRYLATLTVRNLVGK---SDAAVLTIPACDFQAT 424
Q + TK+++ Y + N V K +++ QA
Sbjct 380 GSGVHYSPQQNGLKTTKVSITDLQAHTNYTFEVWSINGVSKQNPGQDQAVSVTVTTNQA- 438
Query 425 HPVMDLKAFPKD---NMLWVEWTTPRESVKKYILEWCV-LSDKAPCITDWQQEDGTVHRT 480
P + PKD + + + W E ILE+ V +K ++ T
Sbjct 439 APSTVTQIQPKDITRHSVSLTW-PEPERPNGVILEYEVKYYEKDQNERTYRIVKTTSRSA 497
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG------PTVRTKKVGKNE 534
++G L Y+ V A G G + PS PTV V +
Sbjct 498 DIKG-LNPLTAYVFHVRARTAAGYGEFSGPFEFTTNTVPSPMIGEGASPTVLLVSVAGSI 556
Query 535 AVL 537
++
Sbjct 557 VLV 559
>sp|P28827|PTPRM_HUMAN Receptor-type tyrosine-protein phosphatase
mu OS=Homo sapiens OX=9606 GN=PTPRM PE=1 SV=2
Length=1452
Score = 117 bits (293), Expect = 2e-25, Method: Composition-based stats.
Identities = 60/395 (15%), Positives = 120/395 (30%), Gaps = 35/395 (9%)
Query 194 IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI 253
+ E +G + V K P P + + ++L N
Sbjct 258 YRCMIRTEGGVGISN----YAELVVKEPPVPIAPPQLASVGATYLWIQLN-ANSINGDGP 312
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
I+ ++Y T + +W+ P D +S+ + L P TEY + + G+G
Sbjct 313 IVAREVEYCTA-SGSWNDRQPVD----STSYKIGHLDPDTEYEISVL-LTRPGEGGTGSP 366
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT----LPPFEANGKILDY--- 366
T P + P ++ R + + W+ + + + Y
Sbjct 367 GPALRTRTKCADPMRGPRKLEVVEV----KSRQITIRWEPFGYNVTRCHSYNLTVHYCYQ 422
Query 367 ---EVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG-KSDAAVLTIPACDFQ 422
+ + S + +T L + N G K ++ D
Sbjct 423 VGGQEQVREEVSWDTENSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELIVQTDEDLP 482
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKK---YILEWCVLSDKAPCITDWQQEDGTVHR 479
P ++ + ++++W P ++ Y + + +S P I D + G V +
Sbjct 483 GAVPTESIQGSTFEEKIFLQWREPTQTYGVITLYEITYKAVSSFDPEI-DLSNQSGRVSK 541
Query 480 T-----YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE 534
+L L Y T+ A G G P + + K + PS + + +
Sbjct 542 LGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKISAPSMPAYELETPLNQTD 601
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
+ P + + Y I T
Sbjct 602 NTVTVMLKPAHSRGAPVSVYQIVVEEERPRRTKKT 636
Score = 88.0 bits (216), Expect = 3e-16, Method: Composition-based stats.
Identities = 44/295 (15%), Positives = 86/295 (29%), Gaps = 27/295 (9%)
Query 350 VWKTLPPFEANG--KILDYEVTLTRWKSHLQN-YTVNATKLTVNLTNDRYLATLTV---- 402
+W L NG I+ EV + V++T + + ++V
Sbjct 298 LWIQLNANSINGDGPIVAREVEYCTASGSWNDRQPVDSTSYKIGHLDPDTEYEISVLLTR 357
Query 403 --RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK-----KYIL 455
G A+ T C P K + + W +V +
Sbjct 358 PGEGGTGSPGPALRTRTKCADPMRGPRKLEVVEVKSRQITIRWEPFGYNVTRCHSYNLTV 417
Query 456 EWCVLSDKAPCITD-WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+C + + + H + NL+ + + + +G + +
Sbjct 418 HYCYQVGGQEQVREEVSWDTENSHPQHTITNLSPYTNVSVKLILMNPEGRKESQELIVQT 477
Query 515 KQAPPSKGPTVRTKKVG-KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD-- 571
+ P PT + + + L+W + G I Y I Y+ + + +++
Sbjct 478 DEDLPGAVPTESIQGSTFEEKIFLQWRE--PTQTYGVITLYEITYKAVSSFDPEIDLSNQ 535
Query 572 -------SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE 619
+ T + L T Y + A T +G FTT A
Sbjct 536 SGRVSKLGNETHFLFFGLYPGTTYSFTIRASTAKGFGPPATNQFTTKISAPSMPA 590
>sp|Q6YI48|PTPRU_CHICK Receptor-type tyrosine-protein phosphatase
U OS=Gallus gallus OX=9031 GN=PTPRU PE=2 SV=1
Length=1434
Score = 117 bits (292), Expect = 3e-25, Method: Composition-based stats.
Identities = 62/383 (16%), Positives = 113/383 (30%), Gaps = 39/383 (10%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
+ + K P P ++ + I++L TN I I++ I+YR + WS++
Sbjct 278 ELIVKEPPTPIAPPQLLRAGSTYLIIQLN-TNSIIGDGPIVRKEIEYRM-TSGPWSEVHA 335
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
+ ++ + L P TEY + + G+G T P +AP
Sbjct 336 VN----MQTYKLWHLDPDTEYEISVL-LTRPGEGGTGKPGPPLISRTKCAEPMRAP---- 386
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT--------VNATK 386
K R + L W+ L + N T NA +
Sbjct 387 KGLAFSEIQSRQLTLQWEPLGYNLTRCHTYSVSLCYRYLVGSGLNQTFRECAKMERNANR 446
Query 387 LTV--NLTNDRYLATLTVRNLVGKSDAAVLTIPAC-DFQATHPVMDLKAFPKDNMLWVEW 443
T+ L L + N G+ + +T D L P ++M++++W
Sbjct 447 YTIKNLLPYRNIHVKLILSNPEGRKEGKEVTFQTDEDVPGGIASESLTFTPLEDMIFLKW 506
Query 444 TTPRESVKKYILEWCVLSDKAPCITDWQQEDG--------TVHRTYLRGNLAESKCYLIT 495
P E I ++ + G ++ NL YL +
Sbjct 507 EEPVEP-NGLITQYEISYQSIESSDPAVNVPGPRRTVSKLRNETYHVFSNLHPGTTYLFS 565
Query 496 VTPVYADGPGSPESIKAYLKQAPPS----KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
V G G + + P+ P+ + +L P + I
Sbjct 566 VRARTGKGFGQTALTEITTNISAPTFDYGDMPSPLGESESTITVLLR----PAQGRGAPI 621
Query 552 RNYTIFYRTIIGNETAVNVDSSH 574
Y + +
Sbjct 622 STYQVIVEEDRPKRIKRELGGQE 644
Score = 90.7 bits (223), Expect = 4e-17, Method: Composition-based stats.
Identities = 67/354 (19%), Positives = 120/354 (34%), Gaps = 43/354 (12%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGG-----RETHLETNFT---LKSEWATHKFADCKAKR 176
P PK L+ + +++ +W+ R + L F +C AK
Sbjct 382 PMRAPKGLAFSEIQSRQLTLQWEPLGYNLTRCHTYSVSLCYRYLVGSGLNQTFREC-AKM 440
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN-PPHNLSVINSEE 235
+ + + + + NI V + N G+ + F V +L+ E+
Sbjct 441 ERNANRYTIKNLLPYRNIHVKLILSNPEGRKEGKEVTFQTDEDVPGGIASESLTFTPLED 500
Query 236 LSSILKLTWTNPSIKSVIILKYNIQYRTKDAS--TWSQIPPEDTAST---RSSFTVQDLK 290
++ L W P + +I +Y I Y++ ++S + P T S + +L
Sbjct 501 ---MIFLKWEEPVEPNGLITQYEISYQSIESSDPAVNVPGPRRTVSKLRNETYHVFSNLH 557
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS-HTQGYRTVQL 349
P T Y+F +R G G + +T AP+F Y PS + T+ +
Sbjct 558 PGTTYLFSVRARTGKGFGQ--------TALTEITTNISAPTFDYGDMPSPLGESESTITV 609
Query 350 VWKTLPPFEANG-KILDYEVTLTRWKSH-LQNYTVNATKLTVNLTNDRYLATLTVRNLVG 407
+ L P + G I Y+V + + ++ V LT D + G
Sbjct 610 L---LRPAQGRGAPISTYQVIVEEDRPKRIKRELGGQECFPVPLTFDDAM-------SRG 659
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
+PA P W P E K Y++ + +S
Sbjct 660 SVHYFGAELPASSLTEAKPFTVGDNQTYSGY----WNPPLEPKKAYLIYFQAMS 709
Score = 89.1 bits (219), Expect = 1e-16, Method: Composition-based stats.
Identities = 59/351 (17%), Positives = 112/351 (32%), Gaps = 40/351 (11%)
Query 300 RCMKEDGKGYWSDWSEEASGITYEDR-PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
RC+ + +G S S A I E P P T ++
Sbjct 262 RCVTQSSRG--SGVSNFAELIVKEPPTPIAPPQLLRAGSTYLIIQLNTNSII-------- 311
Query 359 ANGKILDYEVTLTRWKSHLQNY---TVNATKLTVNLTNDRYLATLTVR----NLVGKSDA 411
+G I+ E+ + KL + Y ++ + GK
Sbjct 312 GDGPIVRKEIEYRMTSGPWSEVHAVNMQTYKLWHLDPDTEYEISVLLTRPGEGGTGKPGP 371
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK---YILEWCVLSDKAPCIT 468
+++ C P + + L ++W ++ + Y + C +
Sbjct 372 PLISRTKCAEPMRAPKGLAFSEIQSRQLTLQWEPLGYNLTRCHTYSVSLCYRYLVGSGLN 431
Query 469 DWQQEDGTVHR---TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK-GPT 524
+E + R Y NL + + + +G + + + P
Sbjct 432 QTFRECAKMERNANRYTIKNLLPYRNIHVKLILSNPEGRKEGKEVTFQTDEDVPGGIASE 491
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS---------SHT 575
T ++ L+W++ NG I Y I Y++I ++ AVNV + T
Sbjct 492 SLTFTPLEDMIFLKWEE--PVEPNGLITQYEISYQSIESSDPAVNVPGPRRTVSKLRNET 549
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT----PKFAQGEIEAIV 622
+ S+L T Y+ + A T +G TT P F G++ + +
Sbjct 550 YHVFSNLHPGTTYLFSVRARTGKGFGQTALTEITTNISAPTFDYGDMPSPL 600
Score = 67.2 bits (162), Expect = 7e-10, Method: Composition-based stats.
Identities = 44/242 (18%), Positives = 89/242 (37%), Gaps = 23/242 (10%)
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQ-ATHPVMDLKAFPKDNMLWVEWTTPR---- 447
++ L ++ G + + + P L+A L ++ T
Sbjct 256 GEQDLYRCVTQSSRGSGVSNFAELIVKEPPTPIAPPQLLRA--GSTYLIIQLNTNSIIGD 313
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV--TPVYADGPG 505
+ + +E+ + S W + +TY +L Y I+V T G G
Sbjct 314 GPIVRKEIEYRMTSGP------WSEVHAVNMQTYKLWHLDPDTEYEISVLLTRPGEGGTG 367
Query 506 SP-ESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
P + + K A P + P + ++ + L+W+ L ++ + ++ YR ++G
Sbjct 368 KPGPPLISRTKCAEPMRAPKGLAFSEIQSRQLTLQWEPLGYNLTRCHTYSVSLCYRYLVG 427
Query 564 NE------TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
+ ++ + YT+ +L V++ EG K+G E TF T + G
Sbjct 428 SGLNQTFRECAKMERNANRYTIKNLLPYRNIHVKLILSNPEGRKEGKEVTFQTDEDVPGG 487
Query 618 IE 619
I
Sbjct 488 IA 489
>sp|Q91694|EPA4B_XENLA Ephrin type-A receptor 4-B OS=Xenopus laevis
OX=8355 GN=epha4-b PE=2 SV=1
Length=985
Score = 115 bits (288), Expect = 6e-25, Method: Composition-based stats.
Identities = 47/240 (20%), Positives = 76/240 (32%), Gaps = 22/240 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHKFADCKAKRDTPTSC 182
PP P+NL VNE + EW + + + ++ L + C
Sbjct 328 PPSAPQNLISNVNE-TSVNLEWSPPQNSGGRPDVSYNLVCKRCGSDLTRCSPCGSGVHYS 386
Query 183 TVDY----------STVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVI 231
N V A N + K P ++ I
Sbjct 387 PQQNGLKTTKVSINDLQAHTNYTFEVWAINGVSKQNPEQDQAVSVTVTTNQAAPSTVTQI 446
Query 232 NSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+E++ + LTW P + +IL+Y ++Y KD ++ + S ++ L
Sbjct 447 QPKEITRHSVSLTWPEPERANGVILEYEVKYYEKD---QNERSYRIVKTASRSADIKGLN 503
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
P T YVF +R G G +S E T PS ++ LV
Sbjct 504 PLTGYVFHVRARTAAGYGEFSGPFEF----TTNTVPSPMIGEGTSPTVLLVSVAGSIVLV 559
Score = 111 bits (277), Expect = 1e-23, Method: Composition-based stats.
Identities = 47/246 (19%), Positives = 89/246 (36%), Gaps = 22/246 (9%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV--------LSDKAPCITDWQ--- 471
+L + + + +EW+ P+ S + + + + L+ +PC +
Sbjct 328 PPSAPQNLISNVNETSVNLEWSPPQNSGGRPDVSYNLVCKRCGSDLTRCSPCGSGVHYSP 387
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-----SIKAYLKQAPPSKGPTVR 526
Q++G +L Y V + +PE S+ QA PS ++
Sbjct 388 QQNGLKTTKVSINDLQAHTNYTFEVWAINGVSKQNPEQDQAVSVTVTTNQAAPSTVTQIQ 447
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA-VNVDSSHTEYTLSSLTSD 585
K++ ++ L W + + NG I Y + Y NE + V ++ + L
Sbjct 448 PKEITRHSVSLTWPE--PERANGVILEYEVKYYEKDQNERSYRIVKTASRSADIKGLNPL 505
Query 586 TLYMVRMAAYTDEGGKD--GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNK 643
T Y+ + A T G + GP F FTT I P L + + ++
Sbjct 506 TGYVFHVRARTAAGYGEFSGP-FEFTTNTVPSPMIGEGTSPTVLLVSVAGSIVLVVILIA 564
Query 644 RDLIKK 649
+I +
Sbjct 565 AFVISR 570
Score = 85.7 bits (210), Expect = 1e-15, Method: Composition-based stats.
Identities = 44/248 (18%), Positives = 78/248 (31%), Gaps = 28/248 (11%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWS--- 270
DP PP + S + + L W+ P + YN+ + +
Sbjct 319 DPASMPCTRPPSAPQNLISNVNETSVNLEWSPPQNSGGRPDVSYNLVCKRCGSDLTRCSP 378
Query 271 -----QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW-SDWSEEASGITYED 324
P+ + ++ DL+ T Y F + + K D + + T +
Sbjct 379 CGSGVHYSPQQNGLKTTKVSINDLQAHTNYTFEVWAINGVSKQNPEQDQAVSVTVTTNQA 438
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA 384
PS +I P +V L W P ANG IL+YEV + ++Y +
Sbjct 439 APST----VTQIQPK-EITRHSVSLTW--PEPERANGVILEYEVKYYEKDQNERSYRIVK 491
Query 385 TK-----LTVNLTNDRYLATLTVRNLV------GKSDAAVLTIPACDFQATHPVMDLKAF 433
T + Y+ + R G + T+P+ L
Sbjct 492 TASRSADIKGLNPLTGYVFHVRARTAAGYGEFSGPFEFTTNTVPSPMIGEGTSPTVLLVS 551
Query 434 PKDNMLWV 441
+++ V
Sbjct 552 VAGSIVLV 559
Score = 68.0 bits (164), Expect = 3e-10, Method: Composition-based stats.
Identities = 45/241 (19%), Positives = 69/241 (29%), Gaps = 34/241 (14%)
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL------ 377
RP AP + +V L W P + Y + R S L
Sbjct 326 TRPPSAPQ-----NLISNVNETSVNLEWSP-PQNSGGRPDVSYNLVCKRCGSDLTRCSPC 379
Query 378 --------QNYTVNATKLTVNLTN--DRYLATLTVRNLVGKS----DAAVLTIPACDFQA 423
Q + TK+++N Y + N V K D AV + A
Sbjct 380 GSGVHYSPQQNGLKTTKVSINDLQAHTNYTFEVWAINGVSKQNPEQDQAVSVTVTTNQAA 439
Query 424 THPVMDLKA-FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
V ++ + + + W E ILE+ V + + T R+
Sbjct 440 PSTVTQIQPKEITRHSVSLTW-PEPERANGVILEYEVKYYEKDQNERSYRIVKTASRSAD 498
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG------PTVRTKKVGKNEAV 536
L Y+ V A G G + PS PTV V + +
Sbjct 499 IKGLNPLTGYVFHVRARTAAGYGEFSGPFEFTTNTVPSPMIGEGTSPTVLLVSVAGSIVL 558
Query 537 L 537
+
Sbjct 559 V 559
>sp|P56741|MYPC_RAT Myosin-binding protein C, cardiac-type OS=Rattus
norvegicus OX=10116 GN=Mybpc3 PE=1 SV=2
Length=1274
Score = 115 bits (287), Expect = 1e-24, Method: Composition-based stats.
Identities = 68/462 (15%), Positives = 135/462 (29%), Gaps = 35/462 (8%)
Query 107 TFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN--FTLKSEW 164
G+ + N+ I P PK +W+ + + L+ +
Sbjct 756 PVGEDQVNLTVKVIDVPDAPAAPKI---SNVGEDSCIVQWEPPAYDGGQPVLGYILERKK 812
Query 165 ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNP 224
+ V E+ V A NA+G + + P
Sbjct 813 KKSYRWMRLNFDLLRELSHEARRMIEGVAYEMRVYAVNAVGMSRPSPASQPFMPIGPPGE 872
Query 225 PHNLSVINSEELSSILKLTWTNPSI-KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P +L+V + + + + L W P + + Y+++Y + S W + + R+S
Sbjct 873 PTHLTVEDVSD--TTVSLKWRPPERVGAGGLDGYSVEYCQEGCSEW--VTALQGLTERTS 928
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSFWYKIDPSHTQ 342
V+DL +FR+R G G E + RP + P +
Sbjct 929 LLVKDLPTGARLLFRVRAHNVAGPGGPIITKEPVTVQEILQRPRLQLPRHLRQTIQKKVG 988
Query 343 GYRTVQLVWKTLPPFEANG-----KILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL 397
+ + ++ P + + EV++ + + A + + Y
Sbjct 989 EPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAAHRT----HSGTYQ 1044
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK-DNMLWVEWTTPRESVKKYILE 456
T+ + N+ D A L + D P +D++ + +EW P++ I
Sbjct 1045 VTVRIENM---EDKATLVLQIVD--KPSPPLDIRVVETWGFSVALEWKPPQDDGNTEIWG 1099
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ V + + + + L Y V G A K+
Sbjct 1100 YTVQKADKKTMEWFTVLEHYRQTHCVVSELIIGNGYYFRVFSHNMVG---SSDRAAATKE 1156
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLP----VDVQNGFIRNY 554
P + + + P I Y
Sbjct 1157 PIFIPRPGITYEPPKYKALDFS--EAPSFTQPLTNRSIIAGY 1196
Score = 107 bits (267), Expect = 2e-22, Method: Composition-based stats.
Identities = 45/220 (20%), Positives = 81/220 (37%), Gaps = 10/220 (5%)
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
D + T+TV+N VG+ D LT+ D + +D+ + V+W P +
Sbjct 744 EDEGVYTVTVKNPVGE-DQVNLTVKVIDVPDAPAAPKISNVGEDSCI-VQWEPPAYDGGQ 801
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRG--NLAESKCYLITVTPVYADGPGSPESI 510
+L + +L K W + + + R + E Y + V V A G P
Sbjct 802 PVLGY-ILERKKKKSYRWMRLNFDLLRELSHEARRMIEGVAYEMRVYAVNAVGMSRPSPA 860
Query 511 -KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAV 568
+ ++ PP + + + V L+W P V G + Y++ Y +
Sbjct 861 SQPFMPIGPPGEPTHLTVEDVSDTTVSLKWRP-PERVGAGGLDGYSVEYCQEGCSEWVTA 919
Query 569 NVDSSH-TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
+ T + L + + R+ A+ G GP T
Sbjct 920 LQGLTERTSLLVKDLPTGARLLFRVRAHNVAG-PGGPIIT 958
>sp|Q9WTL4|INSRR_MOUSE Insulin receptor-related protein OS=Mus
musculus OX=10090 GN=Insrr PE=1 SV=2
Length=1300
Score = 114 bits (286), Expect = 1e-24, Method: Composition-based stats.
Identities = 89/498 (18%), Positives = 148/498 (30%), Gaps = 75/498 (15%)
Query 228 LSVINSEELSSILKLTWTN-PSIKSVIILKYNIQYRT--------------KDASTWSQI 272
L + + + L W +++ +L + + Y+ +W+ +
Sbjct 487 LRFVFNLTEEDRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGTQSWNLL 546
Query 273 PPEDTASTRSS--FTVQDLKPFTEYVFRIRCMK------EDGKGYWSDWSEEASGITYED 324
E S T+ LKP+T+Y +R + +G S T
Sbjct 547 DVELPLSRTQEPGVTLAPLKPWTQYAVFVRAITLTTAEDSPHQGAQ---SPIVYLRTLPA 603
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS----HLQNY 380
P+ S + + + WK PP + NG I Y V R ++ +Y
Sbjct 604 APTVPQDV-----ISTSNSSSHLLVRWK--PPVQRNGNITYYLVLWQRLAEDGDLYINDY 656
Query 381 TVNATKLTV---NLTNDRYLATLTVRNLVGKSD----AAVLTIPACDFQATHPVMDLKAF 433
+L + DR L G +PA + Q + F
Sbjct 657 CHRGLRLPTSSHDTRFDREDPALEAEPEQGCCPCQHSPPGQALPALEAQEVTFQKKFENF 716
Query 434 --PKDNMLWVEWTT------PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+ W P+ +++ E +L QED +
Sbjct 717 LHHAITIPKAPWKVTSINKNPQRDSERHRREAGLLRLGKNNSDFEIQEDKVPRERAILSG 776
Query 486 LAESKCYLITVTPVYAD----GPGSPESIKAYLKQAPPSKGPT--VRTKKVGKNEAVLEW 539
L Y I + G + + A + G V K GK+ L W
Sbjct 777 LRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVAWKAAGKSSVTLHW 836
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS----LTSDTLYMVRMAAY 595
+ P NG I Y I YR + T + V S + L Y ++ A
Sbjct 837 LEPP--DPNGLILKYEIKYRRLGEEATVLCV-SRLRYAKVGGVHLALLPPGNYSAKVRAT 893
Query 596 TDEGGK---DGPEFTFTTPK---FAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKK 649
+ G DG F T + I V PV L+T F KR+
Sbjct 894 SLAGNGSWTDGVTFYITDLEEEDTGGMRIFLTVTPVGFMLLVTLAALGFFYSRKRN---S 950
Query 650 HIWPNVPDPSKSHIAQWS 667
++ +V +P +
Sbjct 951 TLYTSV-NPEYFSASHMY 967
Score = 51.8 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 64/358 (18%), Positives = 106/358 (30%), Gaps = 67/358 (19%)
Query 191 FVNIEVWVEAENALGKVTSDHINFD---PVYKVKPNPPH-NLSVINSEELSSILKLTWTN 246
+ V+V A S H + P P VI++ SS L + W
Sbjct 568 WTQYAVFVRAITLTTAEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKP 627
Query 247 PSIKSVIILKYNI--QYRTKDASTW-----SQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
P ++ I Y + Q +D + + T+S + F +D P E
Sbjct 628 PVQRNGNITYYLVLWQRLAEDGDLYINDYCHRGLRLPTSSHDTRFDRED--PALE----- 680
Query 300 RCMKEDGKGY--WSDWSEEA-------------------SGITYEDRPSKAPSFWYKIDP 338
E G S + IT P K S
Sbjct 681 -AEPEQGCCPCQHSPPGQALPALEAQEVTFQKKFENFLHHAITIPKAPWKVTSINKNPQR 739
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLA 398
+ R L+ L ++ +I + +V R L+ Y
Sbjct 740 DSERHRREAGLL--RLGKNNSDFEIQEDKVPRER------------AILSGLRHFTEYRI 785
Query 399 TLTVRN----LVGKSDAAVL---TIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES-- 449
+ N VG S A + T+P + + KA K + + + W P +
Sbjct 786 DIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVAWKAAGKSS-VTLHWLEPPDPNG 844
Query 450 -VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ KY +++ L ++A + + V +L L Y V G GS
Sbjct 845 LILKYEIKYRRLGEEATVLCVSRLRYAKVGGVHLA--LLPPGNYSAKVRATSLAGNGS 900
>sp|Q9U308|JAC1_CAEEL Juxtamembrane domain-associated catenin
OS=Caenorhabditis elegans OX=6239 GN=jac-1 PE=1 SV=2
Length=1254
Score = 114 bits (286), Expect = 1e-24, Method: Composition-based stats.
Identities = 71/461 (15%), Positives = 137/461 (30%), Gaps = 59/461 (13%)
Query 208 TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDA 266
+ F P+ P V+++ + + W+ P + + Y I+ R
Sbjct 191 PAPASRFLHEDSGIPSAPGVPDVVDAGI--GEVTVVWSAPLQSNGGEVRGYQIEMREFPD 248
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYV--FRIRCMKEDGKGYWSDWSEEASGITYED 324
W + + + V +L T + FR+ G G S+ S E
Sbjct 249 GEWESMGVDHLLKDTT-CRVTNL---TSHEVQFRVSAYGRTGFGPASNPSLPVKIPISET 304
Query 325 --RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS------H 376
S + V L W + Y+V + S +
Sbjct 305 DLATSAGAPLAPGRPTVIAVDGQGVLLEWTPPVADVHSSPPQGYQVEYRVYGSRDWIVAN 364
Query 377 LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA---- 432
Q N + N Y + +N G + ++ + P + A
Sbjct 365 EQLVQENVFTVESLRPNGVYEFRVRGKNQDGLGHPS-MSSGGVAIRPAAPQRHVPARKVS 423
Query 433 ------------FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
D+++ +EW ++ + YI+E+ + D ++ D V
Sbjct 424 ESVQPPGQPQMVEVGDDVVKLEWAPSVQNAR-YIVEYREVGDPEWHTANY---DPIVQNG 479
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP-------SKGPTV----RTKK 529
L + Y V + D S S + + P P + +
Sbjct 480 IQVEGLHRNSTYEFCVISIV-DNIASQPSETSDIIHLRPTCNTSALRPAPNILEAPEFLE 538
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSS---HTEYTLSSLTSDT 586
V ++ + W LP Q + Y + +R + ++ V+ + T+ L D
Sbjct 539 VDGDKITICW--LPAQSQL-PVMGYDVEFRDLQQDDRWYKVNDQPVFACKMTVGDLIMDH 595
Query 587 LYMVRMAAYTDEGGK-DGPEFTFT--TPKFAQGEIEAIVVP 624
Y R+ A+ G P F P + + + P
Sbjct 596 DYQFRVLAHNASGCSQPSPPSDFVHIEPSTNRFSSDTMESP 636
Score = 103 bits (256), Expect = 5e-21, Method: Composition-based stats.
Identities = 74/430 (17%), Positives = 130/430 (30%), Gaps = 56/430 (13%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNF--TLKSEWATHKFADCKAKRDT----- 178
P P + ++ W L++N + +F D + +
Sbjct 205 PSAPGVPDVVDAGIGEVTVVWSAP----LQSNGGEVRGYQIEMREFPDGEWESMGVDHLL 260
Query 179 -PTSCTVDYSTVYFVNIEVWVEAENALG--KVTSDHINF------DPVYKVKPNPPHNLS 229
T+C V T + V V G S + P P +
Sbjct 261 KDTTCRVTNLTSHEVQFRVSAYGRTGFGPASNPSLPVKIPISETDLATSAGAPLAPGRPT 320
Query 230 VINSEELSSILKLTWTNPSIK--SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
VI + + L WT P S Y ++YR + W + + FTV+
Sbjct 321 VIAVDGQG--VLLEWTPPVADVHSSPPQGYQVEYRVYGSRDWIVANEQLV--QENVFTVE 376
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK-------APSFWYKIDPSH 340
L+P Y FR+R +DG G+ S S + P + + S P
Sbjct 377 SLRPNGVYEFRVRGKNQDGLGHPSMSSGGVAIRP--AAPQRHVPARKVSESVQPPGQPQM 434
Query 341 TQ-GYRTVQLVWKTLPPFEANGK-ILDYEVTLTRWKSHLQNYTV--NATKLTVNLTNDRY 396
+ G V+L W P N + I++Y + N ++ N Y
Sbjct 435 VEVGDDVVKLEW---APSVQNARYIVEYREVGDPEWHTANYDPIVQNGIQVEGLHRNSTY 491
Query 397 LATL-TVRNLVGKSDAAVLTI----PACDFQATHPVMDLKAFPK-----DNMLWVEWTT- 445
+ ++ + + + I P C+ A P ++ P+ + + + W
Sbjct 492 EFCVISIVDNIASQPSETSDIIHLRPTCNTSALRPAPNILEAPEFLEVDGDKITICWLPA 551
Query 446 -PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
+ V Y +E+ L + G+L Y V A G
Sbjct 552 QSQLPVMGYDVEFRDLQQDDRWYK--VNDQPVFACKMTVGDLIMDHDYQFRVLAHNASGC 609
Query 505 GSPESIKAYL 514
P ++
Sbjct 610 SQPSPPSDFV 619
Score = 69.9 bits (169), Expect = 8e-11, Method: Composition-based stats.
Identities = 32/211 (15%), Positives = 58/211 (27%), Gaps = 18/211 (9%)
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
A + + P + + V W+ P +S + + + +
Sbjct 187 SAPPPAPASRFLHEDSGIPSAPGVPDVVDAGIGEVTVVWSAPLQSNGGEVRGYQIEMREF 246
Query 465 PCITDWQQEDGT---VHRTYLRGNLAESKCYLITVTPVYADGPGSPE--------SIKAY 513
P +W+ T NL + V+ G G I
Sbjct 247 P-DGEWESMGVDHLLKDTTCRVTNLTSHEV-QFRVSAYGRTGFGPASNPSLPVKIPISET 304
Query 514 ---LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
P V +LEW DV + + Y + YR + V
Sbjct 305 DLATSAGAPLAPGRPTVIAVDGQGVLLEWTPPVADVHSSPPQGYQVEYRVYGSRDWIVAN 364
Query 571 D--SSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ +T+ SL + +Y R+ +G
Sbjct 365 EQLVQENVFTVESLRPNGVYEFRVRGKNQDG 395
Score = 55.2 bits (131), Expect = 3e-06, Method: Composition-based stats.
Identities = 35/213 (16%), Positives = 71/213 (33%), Gaps = 19/213 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATH-KFADCKAKRDTPTSCT 183
PP +P+ + V + ++ EW + + ++ ++
Sbjct 428 PPGQPQMV--EVGDDV-VKLEWAPSVQ---NARYIVEYREVGDPEWHTANYDPIVQNGIQ 481
Query 184 VDYSTVYFVNIEVWVEAE--NALG--KVTSDHINFDPVYKVKPN--PPHNLSV-INSEEL 236
V+ E V + N TSD I+ P P+ L E
Sbjct 482 VEGLH-RNSTYEFCVISIVDNIASQPSETSDIIHLRPTCNTSALRPAPNILEAPEFLEVD 540
Query 237 SSILKLTWTNPSIKSVIILKYNIQYR-TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+ + W P+ + ++ Y++++R + W ++ + + + TV DL +Y
Sbjct 541 GDKITICW-LPAQSQLPVMGYDVEFRDLQQDDRWYKVNDQPVFACKM--TVGDLIMDHDY 597
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
FR+ G S S+ +R S
Sbjct 598 QFRVLAHNASGCSQPSPPSDFVHIEPSTNRFSS 630
>sp|P14616|INSRR_HUMAN Insulin receptor-related protein OS=Homo
sapiens OX=9606 GN=INSRR PE=1 SV=2
Length=1297
Score = 114 bits (286), Expect = 1e-24, Method: Composition-based stats.
Identities = 84/497 (17%), Positives = 142/497 (29%), Gaps = 78/497 (16%)
Query 230 VINSEELSSILKLTWTN-PSIKSVIILKYNIQYRT--------------KDASTWSQIPP 274
V N E IL L W +++ +L + + Y+ +W+ +
Sbjct 490 VSNVTEADRIL-LRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGTQSWNLLDV 548
Query 275 EDTASTRSS--FTVQDLKPFTEYVFRIRCMK---EDGKGYWSDWSEEASGITYEDRPSKA 329
E S T+ LKP+T+Y +R + E+ + S T P+
Sbjct 549 ELPLSRTQEPGVTLASLKPWTQYAVFVRAITLTTEEDSPHQGAQSPIVYLRTLPAAPTVP 608
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV 389
S + + + WK PP + NG + Y V R Y + +
Sbjct 609 QDV-----ISTSNSSSHLLVRWK--PPTQRNGNLTYYLVLWQRLAEDGDLYLNDYCHRGL 661
Query 390 NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD----------NML 439
L + +++ P + L+A N +
Sbjct 662 RLPTSNNDPRFDGEDGDPEAEMESDCCPCQHPPPGQVLPPLEAQEASFQKKFENFLHNAI 721
Query 440 WVE---WT------TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
+ W +P+ ++ L QED + L
Sbjct 722 TIPISPWKVTSINKSPQRDSGRHRRAAGPLRLGGNSSDFEIQEDKVPRERAVLSGLRHFT 781
Query 491 CYLITVTPVYAD----GPGSPESIKAYLKQAPPSKGPT--VRTKKVGKNEAVLEWDQLPV 544
Y I + G + + A + G V + KN +L W + P
Sbjct 782 EYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVAWEASSKNSVLLRWLEPP- 840
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS----LTSDTLYMVRMAAYTDEGG 600
NG I Y I YR + T + V S L Y R+ A + G
Sbjct 841 -DPNGLILKYEIKYRRLGEEATVLCV-SRLRYAKFGGVHLALLPPGNYSARVRATSLAGN 898
Query 601 KD----------GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKH 650
GPE + PV L L+ F KR+ +
Sbjct 899 GSWTDSVAFYILGPEEE----DAGGLHVLLTATPVGLTLLIVLAALGFFYGKKRN---RT 951
Query 651 IWPNVPDPSKSHIAQWS 667
++ +V +P +
Sbjct 952 LYASV-NPEYFSASDMY 967
Score = 57.2 bits (136), Expect = 8e-07, Method: Composition-based stats.
Identities = 29/158 (18%), Positives = 48/158 (30%), Gaps = 17/158 (11%)
Query 190 YFVNIEVWVEAEN----ALGKVTSDHINFDPV-YKVKPNPPHNLSVINSEELSSILKLTW 244
+F + + A N +G + + + ++ P V + + L W
Sbjct 779 HFTEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPG--KVAWEASSKNSVLLRW 836
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD----LKPFTEYVFRIR 300
P + +ILKY I+YR S L P Y R+R
Sbjct 837 LEPPDPNGLILKYEIKYRRLGEEA-----TVLCVSRLRYAKFGGVHLALLPPGNYSARVR 891
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
G G W+D S + E+ + P
Sbjct 892 ATSLAGNGSWTD-SVAFYILGPEEEDAGGLHVLLTATP 928
Score = 53.7 bits (127), Expect = 9e-06, Method: Composition-based stats.
Identities = 52/353 (15%), Positives = 100/353 (28%), Gaps = 57/353 (16%)
Query 191 FVNIEVWVEAENALGKVTSDHINFD---PVYKVKPNPPH-NLSVINSEELSSILKLTWTN 246
+ V+V A + S H + P P VI++ SS L + W
Sbjct 568 WTQYAVFVRAITLTTEEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKP 627
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P+ ++ + Y + W ++ ED + + + L+ T +
Sbjct 628 PTQRNGNLTYYLV--------LWQRL-AEDGDLYLNDYCHRGLRLPT---------SNND 669
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR-------------TVQLV-WK 352
+ + + + + + P + P + P Q T+ + WK
Sbjct 670 PRFDGEDGDPEAEMESDCCPCQHPPPGQVLPPLEAQEASFQKKFENFLHNAITIPISPWK 729
Query 353 ----TLPPFEANGKILDYEVTLTRWKSHL------QNYTVNATKLTVNLTNDRYLATLTV 402
P +G+ L + L+ Y +
Sbjct 730 VTSINKSPQRDSGRHRRAAGPLRLGGNSSDFEIQEDKVPRERAVLSGLRHFTEYRIDIHA 789
Query 403 RN----LVGKSDAAVLTIPACDFQATH--PVMDLKAFPKDNMLWVEWTTPRES---VKKY 453
N VG S A + + P N + + W P + + KY
Sbjct 790 CNHAAHTVGCSAATFVFARTMPHREADGIPGKVAWEASSKNSVLLRWLEPPDPNGLILKY 849
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+++ L ++A + + +L L Y V G GS
Sbjct 850 EIKYRRLGEEATVLCVSRLRYAKFGGVHLA--LLPPGNYSARVRATSLAGNGS 900
>sp|Q64716|INSRR_RAT Insulin receptor-related protein OS=Rattus
norvegicus OX=10116 GN=Insrr PE=1 SV=3
Length=1300
Score = 114 bits (284), Expect = 2e-24, Method: Composition-based stats.
Identities = 89/498 (18%), Positives = 149/498 (30%), Gaps = 75/498 (15%)
Query 228 LSVINSEELSSILKLTWTN-PSIKSVIILKYNIQYRT--------------KDASTWSQI 272
L + + + L W +++ +L + + Y+ +W+ +
Sbjct 487 LRFVFNLTEEDRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGTQSWNLL 546
Query 273 PPEDTASTRSS--FTVQDLKPFTEYVFRIRCMK------EDGKGYWSDWSEEASGITYED 324
E S T+ LKP+T+Y +R + +G S T
Sbjct 547 DVELPLSRTQEPGVTLAPLKPWTQYAVFVRAITLTTAEDSPHQGAQ---SPIVYLRTLPA 603
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS----HLQNY 380
P+ S + + + WK PP + NG I Y V R ++ +Y
Sbjct 604 APTVPQDV-----ISTSNSSSHLLVRWK--PPVQRNGNITYYLVLWQRLAEDGDLYINDY 656
Query 381 TVNATKLTV---NLTNDRYLATLTVRNLVGKSD----AAVLTIPACDFQATHPVMDLKAF 433
+L + DR L G +PA + Q + F
Sbjct 657 CHRGLRLPTSSHDTRFDREDPALEAEPEQGCCPCQHSPPGQALPALEAQEVTFQKKFENF 716
Query 434 --PKDNMLWVEWTT------PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+ W P+ +++ E +L ED +
Sbjct 717 LHHAITIPKAPWKVTSINKNPQRDSERHRRETGLLRLGKNNSDFEIHEDKVPRERAVLSG 776
Query 486 LAESKCYLITVTPVYAD----GPGSPESIKAYLKQAPPSKGPT--VRTKKVGKNEAVLEW 539
L Y I + G + + A + G V K VGK+ +L W
Sbjct 777 LRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVVWKAVGKSSVILHW 836
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS----LTSDTLYMVRMAAY 595
+ P NG I Y I YR + T + V S + L Y ++ A
Sbjct 837 LEPP--DPNGLILKYEIKYRRLGEEATVLCV-SRLRYAKVGGVHLALLPPGNYSAKVRAT 893
Query 596 TDEGGK---DGPEFTFTTPK---FAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKK 649
+ G DG F T P+ I V PV L+ F KR+
Sbjct 894 SLAGNGSWTDGVAFYITGPEEEDTGGLRILLTVTPVGFMLLVMLAALGFFYSKKRN---S 950
Query 650 HIWPNVPDPSKSHIAQWS 667
++ +V +P +
Sbjct 951 TLYTSV-NPEYFSASHMY 967
Score = 40.6 bits (93), Expect = 0.084, Method: Composition-based stats.
Identities = 16/73 (22%), Positives = 25/73 (34%), Gaps = 4/73 (5%)
Query 191 FVNIEVWVEAENALGKVTSDHINFD---PVYKVKPNPPH-NLSVINSEELSSILKLTWTN 246
+ V+V A S H + P P VI++ SS L + W
Sbjct 568 WTQYAVFVRAITLTTAEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKP 627
Query 247 PSIKSVIILKYNI 259
P ++ I Y +
Sbjct 628 PVQRNGNITYYLV 640
>sp|A0JM20|TYRO3_XENTR Tyrosine-protein kinase receptor TYRO3
OS=Xenopus tropicalis OX=8364 GN=tyro3 PE=2 SV=1
Length=881
Score = 113 bits (283), Expect = 2e-24, Method: Composition-based stats.
Identities = 73/414 (18%), Positives = 134/414 (32%), Gaps = 46/414 (11%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPK-EQYTIINRTASSVTF---T 92
V C L+ + I W + + +Q I ++F
Sbjct 39 TVSQGHEAKLNCSLQ-------GMEEPEIQWLKDGVPVQSADQMYIPVDEDHWISFLSLK 91
Query 93 DIASLNI-QLTCNILTFGQLEQNVYGITIISGLPP--EKPKNLSCIVNEGKKMRCEWDGG 149
++ + + C G+ + ++ G+P +PK+LS N M C G
Sbjct 92 NVERPDAGRYWCEAEHSGRKSVSDAIWVMVEGVPYFTLEPKDLSVTPNSPFNMTCAAVGP 151
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS 209
E + W D + + + + EA NA G +S
Sbjct 152 PEP------LVIFWWVG----DSPLGKSESSPSVLQIPGIRERT-AFSCEAHNAKGVSSS 200
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW 269
K P PP N+++ S +TW+ +I IQ ++ +
Sbjct 201 --RTAIVEVKGLPYPPFNVTISKVTG--STATVTWSPGFNSFSLIKSCTIQVQSLHGN-- 254
Query 270 SQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
++ T+ + + DL+P T + R++C E G +S+W + T E P
Sbjct 255 REMYSRLTSVPPFAVVLDDLQPLTNHSVRVQCTNEMGASPFSEW---ITFNTKEKVPQLI 311
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV--NATKL 387
P + T+ + L W+ + P + IL ++V + + V N L
Sbjct 312 PQ-----NVHMTKTDSCLLLDWEDVDPDKEGYNILGFKVQWEQENTTQGELFVQENQANL 366
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
T + + N G + + +A + P M WV
Sbjct 367 TKWNPEKDLTIRICIANAAGCGPWSEFLLAGSKEEAGK-----QRHPHTRMSWV 415
Score = 83.4 bits (204), Expect = 6e-15, Method: Composition-based stats.
Identities = 52/286 (18%), Positives = 88/286 (31%), Gaps = 26/286 (9%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
+ P+ V +S F C I W + K + + S +
Sbjct 129 LEPKDLSVTPNSPFNMTCA------AVGPPEPLVIFWWVGDSPLGKSESS-----PSVLQ 177
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR 150
I +C + + I + GLP P N++ G W G
Sbjct 178 IPGIRERTAF-SCEAHNAKGVSSSRTAIVEVKGLPY-PPFNVTISKVTGSTATVTWSPGF 235
Query 151 ET-HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT- 208
+ L + T++ + P V N V V+ N +G
Sbjct 236 NSFSLIKSCTIQVQSLHGNREMYSRLTSVPPFAVVLDDLQPLTNHSVRVQCTNEMGASPF 295
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT--NPSIKSVIILKYNIQYRTKDA 266
S+ I F+ KV P N+ + S L L W +P + IL + +Q+ ++
Sbjct 296 SEWITFNTKEKVPQLIPQNVHMTK---TDSCLLLDWEDVDPDKEGYNILGFKVQWEQENT 352
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ E+ + P + RI G G WS+
Sbjct 353 TQGELFVQEN------QANLTKWNPEKDLTIRICIANAAGCGPWSE 392
Score = 78.7 bits (192), Expect = 2e-13, Method: Composition-based stats.
Identities = 39/289 (13%), Positives = 82/289 (28%), Gaps = 13/289 (4%)
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
A G + S L + + L + +R + N G S ++ I
Sbjct 148 AVGPPEPLVIFWWVGDSPLGKSESSPSVLQIPGIRERTAFSCEAHNAKGVS-SSRTAIVE 206
Query 419 CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA--PCITDWQQEDGT 476
P + + V W+ S +++ C + ++ + +
Sbjct 207 VKGLPYPPFNVTISKVTGSTATVTWSPGFNSFS--LIKSCTIQVQSLHGNREMYSRLTSV 264
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVGKNEA 535
+ +L + + V G + K+ P P +
Sbjct 265 PPFAVVLDDLQPLTNHSVRVQCTNEMGASPFSEWITFNTKEKVPQLIPQNVHMTKTDSCL 324
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
+L+W+ + D + I + + + + + V + T + D + +A
Sbjct 325 LLDWEDVDPDKEGYNILGFKVQWEQENTTQGELFVQENQANLTKWNPEKDLTIRICIA-- 382
Query 596 TDEGGKDGPEFTFTTPKFAQGEIEAIV-----VPVCLAFLLTTLLGVLF 639
G EF K G+ VP+ L L + V
Sbjct 383 NAAGCGPWSEFLLAGSKEEAGKQRHPHTRMSWVPMVLGILTALVTVVAM 431
>sp|Q92729|PTPRU_HUMAN Receptor-type tyrosine-protein phosphatase
U OS=Homo sapiens OX=9606 GN=PTPRU PE=1 SV=2
Length=1446
Score = 114 bits (284), Expect = 2e-24, Method: Composition-based stats.
Identities = 61/367 (17%), Positives = 113/367 (31%), Gaps = 43/367 (12%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
+ + K P P ++ + I++L TN I I++ I+YR W+++
Sbjct 279 ELIVKEPPTPIAPPQLLRAGPTYLIIQLN-TNSIIGDGPIVRKEIEYRMARGP-WAEVH- 335
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
A + ++ + L P TEY + + G G T P +AP
Sbjct 336 ---AVSLQTYKLWHLDPDTEYEISVL-LTRPGDGGTGRPGPPLISRTKCAEPMRAP---- 387
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV----- 389
K R + L W+ L Y V+L + ++ +
Sbjct 388 KGLAFAEIQARQLTLQWEPLGYNVTRCH--TYTVSLCYHYTLGSSHNQTIRECVKTEQGV 445
Query 390 -------NLTNDRYLATLTVRNLVGKSDAAVLTIPAC-DFQATHPVMDLKAFPKDNMLWV 441
L L + N G+ + +T D + L P ++M+++
Sbjct 446 SRYTIKNLLPYRNVHVRLVLTNPEGRKEGKEVTFQTDEDVPSGIAAESLTFTPLEDMIFL 505
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG--------TVHRTYLRGNLAESKCYL 493
+W P+E I ++ + G ++ NL YL
Sbjct 506 KWEEPQEP-NGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLHPGTTYL 564
Query 494 ITVTPVYADGPGSPESIKAYLKQAPPS----KGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
+V G G + + PS P+ + +L P +
Sbjct 565 FSVRARTGKGFGQAALTEITTNISAPSFDYADMPSPLGESENTITVLLR----PAQGRGA 620
Query 550 FIRNYTI 556
I Y +
Sbjct 621 PISVYQV 627
Score = 90.7 bits (223), Expect = 4e-17, Method: Composition-based stats.
Identities = 67/356 (19%), Positives = 123/356 (35%), Gaps = 47/356 (13%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDG----GRETHLET-----NFTLKSEWATHKFADCKAK 175
P PK L+ + +++ +W+ H T ++TL S +C K
Sbjct 383 PMRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYTVSLCYHYTLGSSH-NQTIRECV-K 440
Query 176 RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN-PPHNLSVINSE 234
+ S + + + N+ V + N G+ + F V +L+ E
Sbjct 441 TEQGVSRYTIKNLLPYRNVHVRLVLTNPEGRKEGKEVTFQTDEDVPSGIAAESLTFTPLE 500
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP-----EDTASTRSSFTVQDL 289
+ ++ L W P + +I +Y I Y++ ++S + P + +L
Sbjct 501 D---MIFLKWEEPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNL 557
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS-HTQGYRTVQ 348
P T Y+F +R G G + +T APSF Y PS + T+
Sbjct 558 HPGTTYLFSVRARTGKGFGQ--------AALTEITTNISAPSFDYADMPSPLGESENTIT 609
Query 349 LVWKTLPPFEANG-KILDYEVTLTRWKSHLQNYTVNAT-KLTVNLTNDRYLATLTVRNLV 406
++ L P + G I Y+V + ++ V LT + LA
Sbjct 610 VL---LRPAQGRGAPISVYQVIVEEERARRLRREPGGQDCFPVPLTFEAALAR------- 659
Query 407 GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE-WTTPRESVKKYILEWCVLS 461
++ + A+ + DN + W P E K Y++ + S
Sbjct 660 -----GLVHYFGAELAASSLPEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQAAS 710
Score = 88.4 bits (217), Expect = 2e-16, Method: Composition-based stats.
Identities = 47/279 (17%), Positives = 89/279 (32%), Gaps = 25/279 (9%)
Query 361 GKILDYEVTLTRWKSHLQNY---TVNATKLTVNLTNDRYLATLTVR----NLVGKSDAAV 413
G I+ E+ + ++ KL + Y ++ + G+ +
Sbjct 315 GPIVRKEIEYRMARGPWAEVHAVSLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPL 374
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK---YILEWCVLSDKAPCITDW 470
++ C P A + L ++W +V + Y + C
Sbjct 375 ISRTKCAEPMRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYTVSLCYHYTLGSSHNQT 434
Query 471 QQEDGTVH---RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK-GPTVR 526
+E Y NL + + + +G + + + PS
Sbjct 435 IRECVKTEQGVSRYTIKNLLPYRNVHVRLVLTNPEGRKEGKEVTFQTDEDVPSGIAAESL 494
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS---------SHTEY 577
T ++ L+W++ NG I Y I Y++I ++ AVNV + T +
Sbjct 495 TFTPLEDMIFLKWEE--PQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYH 552
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
S+L T Y+ + A T +G TT A
Sbjct 553 VFSNLHPGTTYLFSVRARTGKGFGQAALTEITTNISAPS 591
Score = 64.1 bits (154), Expect = 6e-09, Method: Composition-based stats.
Identities = 42/229 (18%), Positives = 76/229 (33%), Gaps = 23/229 (10%)
Query 407 GKSDAAVLTIPACDFQ-ATHPVMDLKAFPKDNMLWVEWTTPR----ESVKKYILEWCVLS 461
G + + + P L+A P L ++ T + + +E+ +
Sbjct 271 GAGVSNFAELIVKEPPTPIAPPQLLRAGP--TYLIIQLNTNSIIGDGPIVRKEIEYRM-- 326
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV---TPVYADGPGSPESIKAYLKQAP 518
W + +TY +L Y I+V P + + K A
Sbjct 327 ----ARGPWAEVHAVSLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLISRTKCAE 382
Query 519 PSKGP-TVRTKKVGKNEAVLEWDQLPVDVQN------GFIRNYTIFYRTIIGNETAVNVD 571
P + P + ++ + L+W+ L +V +YT+ V +
Sbjct 383 PMRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYTVSLCYHYTLGSSHNQTIRECVKTE 442
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
+ YT+ +L VR+ EG K+G E TF T + I A
Sbjct 443 QGVSRYTIKNLLPYRNVHVRLVLTNPEGRKEGKEVTFQTDEDVPSGIAA 491
>sp|G4SLH0|TTN1_CAEEL Titin homolog OS=Caenorhabditis elegans
OX=6239 GN=ttn-1 PE=1 SV=2
Length=18562
Score = 114 bits (285), Expect = 2e-24, Method: Composition-based stats.
Identities = 59/354 (17%), Positives = 119/354 (34%), Gaps = 32/354 (9%)
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-I 253
E V+ +N G+V FD P+ P ++SV+ +E S L + WT P+ +
Sbjct 14127 EYEVKLKNEFGEV---AQKFDVKVNDTPSAPGDVSVVKAE--SDCLHIEWTAPTEDNGAE 14181
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ Y I+ + + ++ + ++S+ V DL+ T Y+ RI + + G G + +
Sbjct 14182 VTSYVIEKKESGRRKFHKVATVN--GKKTSYVVDDLEIETPYIVRIAAVNKFGTGEFIET 14239
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
+G ++ + P + + L W P + + Y+V
Sbjct 14240 KPVQTGSPFQVPTVEFPPTIDNVT------STSCSLSW-PKPIEDGGSPVYGYDVYKREN 14292
Query 374 KSHLQNYTVNATKLT------VNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
+ Q T + Y + N G + + + P
Sbjct 14293 EGEWQKMNGEELVFTESFNVRALSSGKEYEFKIEACNEAGLRSNSNVVSKKLTVEGLVPE 14352
Query 428 MDLK----AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW--QQEDGTVHRTY 481
+ L ++ + V W + E K++++++ D + +
Sbjct 14353 IILDMPMVKVLDNDKVEVTWKSDGE--KEFVVQYKSDGSSIWASVDIGGPRSESAATSKC 14410
Query 482 LRGNLAESKCYLITVTPVYADGPG---SPESIKAYLKQAPPSKGPTVRTKKVGK 532
+ L E Y+ V G G P L P ++ K+ K
Sbjct 14411 IIDGLREGIPYVFRVAARNQHGTGEFSEPTIPVVVLADDAPRVLKAIKPVKIPK 14464
Score = 98.4 bits (243), Expect = 3e-19, Method: Composition-based stats.
Identities = 67/419 (16%), Positives = 142/419 (34%), Gaps = 50/419 (12%)
Query 31 ISPESPVVQLHSNFTAVCVLK----EKCMDYFHVNANYIVWKTNHFTIPKEQYTIINR-- 84
+S PV+ + + ++ + V+ + + + + +++
Sbjct 14060 VSETKPVITVDKDDQFSLLVAYDSNPEASFSMTVDGKDLEFDG------RSRIDVVDDGL 14113
Query 85 --TASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKM 142
T V+ TD ++L FG++ Q + P P ++S + E +
Sbjct 14114 KLTKRGVSKTDAGEYEVKLK---NEFGEVAQKF---DVKVNDTPSAPGDVSVVKAESDCL 14167
Query 143 RCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
EW E + T++ ++ + + + A + + V V + A
Sbjct 14168 HIEWTAPTEDNGAEVTSYVIEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAA 14227
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNL-SVINSE----ELSSILKLTWTNP-SIKSVII 254
N G F V+ P + +V S+ L+W P +
Sbjct 14228 VNKFGTGE-----FIETKPVQTGSPFQVPTVEFPPTIDNVTSTSCSLSWPKPIEDGGSPV 14282
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
Y++ Y+ ++ W ++ E+ T SF V+ L EY F+I E G S+
Sbjct 14283 YGYDV-YKRENEGEWQKMNGEELVFTE-SFNVRALSSGKEYEFKIEACNEAGLRSNSNVV 14340
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE-----VT 369
+ +T E P + V++ WK+ E ++ Y+ +
Sbjct 14341 SKK--LTVEGL---VPEIILDMPMVKVLDNDKVEVTWKSDGEKE---FVVQYKSDGSSIW 14392
Query 370 LTRWKSHLQNYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
+ ++ + +K ++ + Y+ + RN G + + TIP P
Sbjct 14393 ASVDIGGPRSESAATSKCIIDGLREGIPYVFRVAARNQHGTGEFSEPTIPVVVLADDAP 14451
Score = 83.0 bits (203), Expect = 1e-14, Method: Composition-based stats.
Identities = 67/434 (15%), Positives = 132/434 (30%), Gaps = 78/434 (18%)
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD 265
K SD ++ + KP ++ + L WT + Y +Q + +
Sbjct 15492 KSESDKVS-ELKQIGKPE--------YVSSTATSIALKWT----SDNDEVTYTVQMKEAN 15538
Query 266 A-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE--EASGITY 322
+ W+ + E + S T+ LK T Y+FR+ + G+ S+ SE E T
Sbjct 15539 SKRPWAVVAKEI---SECSATIAQLKEGTSYLFRVIAQNKTGQTVTSEQSESIECKDTTE 15595
Query 323 EDRP--SKAPSFWYKIDPSHTQ------GYRTVQLVWKTLPPFEANGKILDYEVTLTRWK 374
+P + AP+ + T+ G+ ++ W +GK +W
Sbjct 15596 SKKPAFTNAPTDLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGK--------RQWI 15647
Query 375 SHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGKSDAA-----------------VLT 415
++ AT LT+ +D + V+N G + + T
Sbjct 15648 ENI----AGATSLTIGEMREDDEGEYKIVVKNTAGSVEHSCKLTMDQLPEINRVDRYAST 15703
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
+ + + P+ ++W+ ++E ++
Sbjct 15704 LVFDKGETVKLRLSFSGRPQPEVIWI-------DNNGKVIE-------ESRKMKIEKTVL 15749
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
T + + + + + G + P+ + +
Sbjct 15750 NTVLTINSIDSQDQGEFALKIKNR----CGEDKYAIGIQVTDRPAAPGKPAVEDQNVDSV 15805
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
L W P + +RNYT+ T G + TL +L Y R+ A
Sbjct 15806 RLRW-AAPTNDGGSPVRNYTVEMCTEKGKTWTKAEVTKQAFITLFNLVPGESYRFRVRAD 15864
Query 596 TDEG-GKDGPEFTF 608
G + E
Sbjct 15865 NTFGQSEPSDESEL 15878
Score = 73.0 bits (177), Expect = 1e-11, Method: Composition-based stats.
Identities = 48/328 (15%), Positives = 106/328 (32%), Gaps = 29/328 (9%)
Query 28 CGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTAS 87
C +I +P + T+ + K++ + V N K Y + +
Sbjct 14166 CLHIEWTAPTEDNGAEVTSYVIEKKE----SGRRKFHKVATVNG---KKTSYVVDDLEIE 14218
Query 88 SVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEW- 146
+ IA++N T + ++ PP N++ W
Sbjct 14219 TPYIVRIAAVNKFGTGEFIETKPVQTGSPFQVPTVEFPPTID-NVT-----STSCSLSWP 14272
Query 147 DGGRETHLETN-FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
+ + + ++ + T + E +EA N G
Sbjct 14273 KPIEDGGSPVYGYDVYKRENEGEWQKMNGEELVFTESFNVRALSSGKEYEFKIEACNEAG 14332
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEEL-SSILKLTWTNPSIKSVIILKYNIQYRTK 264
++ ++ + P L + + L + +++TW + K ++ +QY++
Sbjct 14333 LRSNSNVVSKKLTVEGLVPEIILDMPMVKVLDNDKVEVTWKSDGEK-----EFVVQYKSD 14387
Query 265 DASTWSQIP---PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+S W+ + P ++ S + L+ YVFR+ + G G +S+ + +
Sbjct 14388 GSSIWASVDIGGPRSESAATSKCIIDGLREGIPYVFRVAARNQHGTGEFSEPTIPVVVLA 14447
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
AP I P ++L
Sbjct 14448 -----DDAPRVLKAIKPVKIPKKGELRL 14470
Score = 72.6 bits (176), Expect = 2e-11, Method: Composition-based stats.
Identities = 40/279 (14%), Positives = 88/279 (32%), Gaps = 37/279 (13%)
Query 356 PFEANG-KILDYEV----TLTRWKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGK 408
P E NG ++ Y + + R + T V+ Y+ + N G
Sbjct 14174 PTEDNGAEVTSYVIEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNKFGT 14233
Query 409 SDAAVLTIPACDFQATHPVMDLKAF---PKDNMLWVEWTTPRESVKKYILEWCVLSDKAP 465
+ P ++ + W P E + + V +
Sbjct 14234 GEFIETKPVQTGSPFQVPTVEFPPTIDNVTSTSCSLSWPKPIEDGGSPVYGYDVYKRENE 14293
Query 466 CITDWQQEDGT---VHRTYLRGNLAESKCYLITVTPVYADGPGSPESI---KAYLKQAPP 519
+WQ+ +G ++ L+ K Y + G S ++ K ++ P
Sbjct 14294 G--EWQKMNGEELVFTESFNVRALSSGKEYEFKIEACNEAGLRSNSNVVSKKLTVEGLVP 14351
Query 520 ---SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNV----- 570
P V+ ++ + W +G + + + Y++ + +V++
Sbjct 14352 EIILDMPMVKVLD--NDKVEVTWKS------DGE-KEFVVQYKSDGSSIWASVDIGGPRS 14402
Query 571 -DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
++ ++ + L Y+ R+AA G + E T
Sbjct 14403 ESAATSKCIIDGLREGIPYVFRVAARNQHGTGEFSEPTI 14441
Score = 68.7 bits (166), Expect = 2e-10, Method: Composition-based stats.
Identities = 52/261 (20%), Positives = 89/261 (34%), Gaps = 30/261 (11%)
Query 195 EVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV- 252
V V AE+ LG+ + + KP+ P +L E + L+W P +
Sbjct 14800 TVRVIAESPLGQCIKEIPLKI----IDKPSAPCDLQFK--EVTEDSVFLSWQPPLETNGA 14853
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ Y I+ + D + W P T+ +F +DL Y FRI + E G+ S+
Sbjct 14854 PLTGYVIERKAVDNNRWR--PCGQVKPTKLTFVAEDLFCNQVYGFRILAVNEVGE---SE 14908
Query 313 WSEEASGITYEDRPSKA-------PSFWYKIDPSHT--QGYRTVQLVWKTLPPFEANGKI 363
+ +T E + P P T V L W+ P K+
Sbjct 14909 PCDTVDVLTLESSEPVSESSELFVPKIAILRTPQVTVAVDETKVTLRWEECPETSLY-KV 14967
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT------IP 417
+V + W + N N K + Y+ +T + S + T +P
Sbjct 14968 ERKKVGDSDW-LEIANTDRNKFKDRSLTESGEYVYQVTATGIHAVSSPSEETNPVKILVP 15026
Query 418 ACDFQATHPVMDLKAFPKDNM 438
+ A+ A ++
Sbjct 15027 GSEMPASKTEKKTDAAKSESE 15047
Score = 66.0 bits (159), Expect = 2e-09, Method: Composition-based stats.
Identities = 48/278 (17%), Positives = 92/278 (33%), Gaps = 18/278 (6%)
Query 58 FHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYG 117
F Y+ W + I T + I +++ + NI E
Sbjct 10297 FSRKPIYVKWMRDDREIRVAYGKASVETTDDSSVLVIKNIDGKDVGNIYAVFDSEYRSAM 10356
Query 118 ITIISGLPPEKPKNLSCIVNE---GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA 174
+ +P + S E GK + + + + ++
Sbjct 10357 ARLDLRVPCKITLESSSNAPEIVAGKNLDLSF---KISGYPLPTNIELLHNNENLRTRSD 10413
Query 175 KRDTPTSCTVDYSTVYFV-NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS 233
D S ++ + + E+ + +N + D + + P +L V ++
Sbjct 10414 VTDFDDSISIRMKRLKLEDSGEIKIIGKN---DSSEDQLRIPINVIEVTSKPTSLQVTST 10470
Query 234 EELSSILKLTWTNPSIKSVIIL-KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
E + LTW+ P+ + + +Y ++ +T D W T S V L
Sbjct 10471 ERE--TVTLTWSLPTELNGSNVNEYLVERKTVDGGRWRHA----CTVTDSRAVVDGLFSG 10524
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
TEYVFR+ + G+ SD + EA+ E+ P
Sbjct 10525 TEYVFRVVAVNGAGQSAPSD-TIEATTQAEEEIDETVP 10561
Score = 60.6 bits (145), Expect = 7e-08, Method: Composition-based stats.
Identities = 31/118 (26%), Positives = 44/118 (37%), Gaps = 9/118 (8%)
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
E V EN GK SD P P ++ + S+ K W P I
Sbjct 8924 EYTVVLENKYGKDESD---LHITMVDTPLKPRKAQLVALTDTSATFK--WLPPHTGESDI 8978
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
L Y + R+ ++ W I +FT +L P Y FRI + G+G S+
Sbjct 8979 LHYIVMRRSTESRRWRNIGHV----QEKTFTAIELVPNEFYAFRIVAVNGFGEGAPSE 9032
Score = 60.3 bits (144), Expect = 1e-07, Method: Composition-based stats.
Identities = 40/260 (15%), Positives = 87/260 (33%), Gaps = 46/260 (18%)
Query 360 NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
NG L +T + + + T ++ + + +G + IP
Sbjct 14769 NGTPLKAIAVVTEYDDSVSVRMKDVT------LDNSGTVRVIAESPLG---QCIKEIPLK 14819
Query 420 DFQATHPVMDLK-AFPKDNMLWVEWTTPRE----SVKKYILEWCVLSDKAPCITDWQ--- 471
DL+ ++ +++ W P E + Y++E KA W+
Sbjct 14820 IIDKPSAPCDLQFKEVTEDSVFLSWQPPLETNGAPLTGYVIE-----RKAVDNNRWRPCG 14874
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP----------------ESIKAYLK 515
Q T T++ +L ++ Y + V G P ES + ++
Sbjct 14875 QVKPTKL-TFVAEDLFCNQVYGFRILAVNEVGESEPCDTVDVLTLESSEPVSESSELFVP 14933
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT 575
+ + P V V + + L W++ P Y + + + ++ ++
Sbjct 14934 KIAILRTPQVTV-AVDETKVTLRWEECPETSL------YKVERKKVGDSDWLEIANTDRN 14986
Query 576 EYTLSSLTSDTLYMVRMAAY 595
++ SLT Y+ ++ A
Sbjct 14987 KFKDRSLTESGEYVYQVTAT 15006
Score = 58.7 bits (140), Expect = 3e-07, Method: Composition-based stats.
Identities = 45/294 (15%), Positives = 83/294 (28%), Gaps = 48/294 (16%)
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD-HINFDPVYKVKPNPPHNLSVINSEE 235
D T+ + I + EN GK + + K P P ++ +
Sbjct 15335 DGTAQLTISKTDSAHSGI-YKLNVENDAGKGKVEIALRIKGAAKGAPGIPTGP-IVFDDV 15392
Query 236 LSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
S + +W P I YN++ + W Q + F L+ T+
Sbjct 15393 TESSAEFSWKAPENNGGCEITGYNVERKESKNKGWKQCG----KTKELKFKADGLEEGTD 15448
Query 295 YVFRIRCMKEDGKG------------------YWSDWSEEASGITYEDRPSKAPSFWYKI 336
Y ++ + G G S+ SE + D+ S+
Sbjct 15449 YDVKVSAVNTMGTGSALEGKITTLKKKEETGKQKSEKSESDEKKSESDKVSELKQIGKPE 15508
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL------TRWKSHLQNYTVNATKLTVN 390
S T ++ L W + + Y V + W + + + +
Sbjct 15509 YVSST--ATSIALKWTSDNDE------VTYTVQMKEANSKRPWAVVAKEISECSATIAQL 15560
Query 391 LTNDRYLATLTVRNLVG---KSDAAVLTIPACDFQATHP-----VMDLKAFPKD 436
YL + +N G S+ + ++ P DL A
Sbjct 15561 KEGTSYLFRVIAQNKTGQTVTSEQSESIECKDTTESKKPAFTNAPTDLTAVKNG 15614
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 26/123 (21%), Positives = 46/123 (37%), Gaps = 8/123 (7%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA--VNVDSSHTE 576
PS V K + +EW P + + +Y I + + V+ T
Sbjct 14151 PSAPGDVSVVKAESDCLHIEWTA-PTEDNGAEVTSYVIEKKESGRRKFHKVATVNGKKTS 14209
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK--FAQGEIEAIVVPVCLAFLLTTL 634
Y + L +T Y+VR+AA G EF T P + ++ + P + + +T
Sbjct 14210 YVVDDLEIETPYIVRIAAVNKFGTG---EFIETKPVQTGSPFQVPTVEFPPTIDNVTSTS 14266
Query 635 LGV 637
+
Sbjct 14267 CSL 14269
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 48/288 (17%), Positives = 86/288 (30%), Gaps = 24/288 (8%)
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND 394
+ + S V + WK Y VT T S + K+ + N
Sbjct 15206 EGEISAQVAETGVSVEWKKDGKALDA----SYTVTSTGGVSTV--------KIPIVDVNT 15253
Query 395 RYLATLTVRNLVGKSDAAVL--TIPACDFQATHPVMDLKAFPKDNMLWVEWT-TPRESVK 451
+ T V++ G + + T+ + + ++ + + S
Sbjct 15254 SGVFTCKVKSSEGDEEEVSIAVTVKLPEVPKVEAEQSIVEVKVGDVAKLSAKISEPASSV 15313
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE--- 508
+ + + + DGT T + + A S Y + V G G E
Sbjct 15314 NWTKDDKPIKEDGNVKAQ-LSPDGTAQLTISKTDSAHSGIYKLNVE--NDAGKGKVEIAL 15370
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF-IRNYTIFYRTIIGNETA 567
IK K AP + V ++ A W + G I Y + +
Sbjct 15371 RIKGAAKGAPGIPTGPIVFDDVTESSAEFSWKA--PENNGGCEITGYNVERKESKNKGWK 15428
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ 615
+ ++ L T Y V+++A G E TT K +
Sbjct 15429 QCGKTKELKFKADGLEEGTDYDVKVSAVNTMGTGSALEGKITTLKKKE 15476
Score = 55.2 bits (131), Expect = 3e-06, Method: Composition-based stats.
Identities = 41/272 (15%), Positives = 80/272 (29%), Gaps = 36/272 (13%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
+P P +E+ + + + PS Y ++ R D W ++
Sbjct 17154 RPGLPRPSGASKTEQ----VTMAFDAPS--EGPADSYEVERRCPDQREW----VSCGSTK 17203
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP--SKAPSFWYKIDP 338
++ L P TEY+FR+ + G G WS+ + + P + +P +
Sbjct 17204 SLELEIKGLTPNTEYIFRVAGKNKQGLGEWSEMTSTLKTASVGQAPQFTISPQSKIIANR 17263
Query 339 SHT-------QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL 391
G T + W Y+ L + +T +NL
Sbjct 17264 DDEFEIAVEFSGTPTPSVKW--------------YKENLQIVPDEKIDVATTSTSSILNL 17309
Query 392 TNDRY--LATLTVRNLVG-KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE 448
+ + N +G S + +TI L
Sbjct 17310 KSQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTLQKALNNESA 17369
Query 449 SVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ I+ C +S ++ W ++D +
Sbjct 17370 QAGQQIMLTCRISSRSESTVAWFKDDERIESA 17401
Score = 54.1 bits (128), Expect = 7e-06, Method: Composition-based stats.
Identities = 31/162 (19%), Positives = 47/162 (29%), Gaps = 7/162 (4%)
Query 458 CVLSDKAPCITDWQ-QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
VLS+ P D + + + Y+ TV V + G ES
Sbjct 8889 RVLSNGEPVSFDVKYEIYDNIASLYIPKMSKRDGG-EYTV--VLENKYGKDESDLHITMV 8945
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
P K + + A +W LP I +Y + R+
Sbjct 8946 DTPLKPRKAQLVALTDTSATFKW--LPPHTGESDILHYIVMRRSTESRRWRNIGHVQEKT 9003
Query 577 YTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGE 617
+T L + Y R+ A G G T + Q E
Sbjct 9004 FTAIELVPNEFYAFRIVAVNGFGEGAPSEIIEVNTLDYDQEE 9045
Score = 54.1 bits (128), Expect = 8e-06, Method: Composition-based stats.
Identities = 20/107 (19%), Positives = 37/107 (35%), Gaps = 2/107 (2%)
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTL 579
SK +++ + L W LP ++ + Y + +T+ G + + +
Sbjct 10460 SKPTSLQVTSTERETVTLTWS-LPTELNGSNVNEYLVERKTVDGGRWRHACTVTDSRAVV 10518
Query 580 SSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVPV 625
L S T Y+ R+ A G TT + + PV
Sbjct 10519 DGLFSGTEYVFRVVAVNGAGQSAPSDTIEATTQAEEEIDETVPTSPV 10565
Score = 54.1 bits (128), Expect = 8e-06, Method: Composition-based stats.
Identities = 28/180 (16%), Positives = 52/180 (29%), Gaps = 23/180 (13%)
Query 362 KILDYEVTLTRWKSHLQNYTVNATKLT-----------VNLTNDRYLATLTVRNLVGKSD 410
KI Y + H + +T D + +N S
Sbjct 10389 KISGYPLPTNIELLHNNENLRTRSDVTDFDDSISIRMKRLKLEDSGEIKIIGKND---SS 10445
Query 411 AAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRESVKKYILEWCVLSDKAPCITD 469
L IP + T L+ + + + W+ P E + E+ ++ K
Sbjct 10446 EDQLRIPINVIEVTSKPTSLQVTSTERETVTLTWSLPTELNGSNVNEY-LVERKTVDGGR 10504
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-SIKAYLK------QAPPSKG 522
W+ + L Y+ V V G +P +I+A + + P+
Sbjct 10505 WRHACTVTDSRAVVDGLFSGTEYVFRVVAVNGAGQSAPSDTIEATTQAEEEIDETVPTSP 10564
Score = 53.7 bits (127), Expect = 9e-06, Method: Composition-based stats.
Identities = 16/86 (19%), Positives = 33/86 (38%), Gaps = 3/86 (3%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN--ETAVNVDSSHTE 576
PS ++ K+V ++ L W P++ + Y I + + N V +
Sbjct 14824 PSAPCDLQFKEVTEDSVFLSWQP-PLETNGAPLTGYVIERKAVDNNRWRPCGQVKPTKLT 14882
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ L + +Y R+ A + G +
Sbjct 14883 FVAEDLFCNQVYGFRILAVNEVGESE 14908
Score = 52.9 bits (125), Expect = 2e-05, Method: Composition-based stats.
Identities = 30/158 (19%), Positives = 55/158 (35%), Gaps = 10/158 (6%)
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
+NG+ + ++V + + Y +K D T+ + N GK D +
Sbjct 8886 PRLRVLSNGEPVSFDVKYEIYDNIASLYIPKMSK------RDGGEYTVVLENKYGK-DES 8938
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQ 472
L I D L A + + +W P + + IL + V+ W+
Sbjct 8939 DLHITMVDTPLKPRKAQLVALTDTSATF-KWLPPH-TGESDILHYIVMRRSTESRR-WRN 8995
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
+T+ L ++ Y + V G G+P I
Sbjct 8996 IGHVQEKTFTAIELVPNEFYAFRIVAVNGFGEGAPSEI 9033
Score = 51.4 bits (121), Expect = 6e-05, Method: Composition-based stats.
Identities = 44/281 (16%), Positives = 85/281 (30%), Gaps = 30/281 (11%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNV 115
++ I N + + SV D+ N T ++ L Q +
Sbjct 14755 EFSGFPIPTIHLTNNGTPLKAIAVVTEYDDSVSVRMKDVTLDNSG-TVRVIAESPLGQCI 14813
Query 116 YGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEW-ATHKFADC 172
I + P P +L + W ET+ T + ++ + +++ C
Sbjct 14814 KEIPLKIIDKPSAPCDLQFKEVTEDSVFLSWQPPLETNGAPLTGYVIERKAVDNNRWRPC 14873
Query 173 KAKRDTPTSCTVDYSTVY-FVNIEVWVEAENALG-KVTSDHINFDPVYK----------- 219
+ PT T ++ + A N +G D ++ +
Sbjct 14874 GQVK--PTKLTFVAEDLFCNQVYGFRILAVNEVGESEPCDTVDVLTLESSEPVSESSELF 14931
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
V + + + L W S Y ++ + S W E +
Sbjct 14932 VPKIAILRTPQVTVAVDETKVTLRWEECPETS----LYKVERKKVGDSDW----LEIANT 14983
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
R+ F + L EYV+++ G S SEE + +
Sbjct 14984 DRNKFKDRSLTESGEYVYQVTA---TGIHAVSSPSEETNPV 15021
Score = 49.9 bits (117), Expect = 2e-04, Method: Composition-based stats.
Identities = 46/231 (20%), Positives = 77/231 (33%), Gaps = 36/231 (16%)
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG-KILDYEVTLT-----RWKSHL 377
D+PS +V L W+ PP E NG + Y + RW+
Sbjct 14822 DKPSAPCDL-----QFKEVTEDSVFLSWQ--PPLETNGAPLTGYVIERKAVDNNRWRPCG 14874
Query 378 QNYTVNATKLTVNLT-NDRYLATLTVRNLVGKSDA----AVLTIPACDFQATHPVM---- 428
Q T + +L N Y + N VG+S+ VLT+ + + + +
Sbjct 14875 QVKPTKLTFVAEDLFCNQVYGFRILAVNEVGESEPCDTVDVLTLESSEPVSESSELFVPK 14934
Query 429 -------DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
+ + + + W E+ + K +DW + T +
Sbjct 14935 IAILRTPQVTVAVDETKVTLRWEECPETSLYKV------ERKKVGDSDWLEIANTDRNKF 14988
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP-SKGPTVRTKKVG 531
+L ES Y+ VT SP +K P S+ P +T+K
Sbjct 14989 KDRSLTESGEYVYQVTATGIHAVSSPSEETNPVKILVPGSEMPASKTEKKT 15039
Score = 46.4 bits (108), Expect = 0.002, Method: Composition-based stats.
Identities = 39/250 (16%), Positives = 76/250 (30%), Gaps = 31/250 (12%)
Query 548 NGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
G +Y + R E + E + LT +T Y+ R+A +G + E T
Sbjct 17178 EGPADSYEVERRCPDQREWVSCGSTKSLELEIKGLTPNTEYIFRVAGKNKQGLGEWSEMT 17237
Query 608 FTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWS 667
T + G+ + + + + P PS +W
Sbjct 17238 STLKTASVGQAPQFTISPQSKIIAN---------RDDEFEIAVEFSGTPTPS----VKWY 17284
Query 668 PHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSG 727
D + + + +++ E N + + ++ +
Sbjct 17285 KENLQIVPDEKID-VATTSTSSILNLKSQEENGTFNCLIENELGQASASCQVTIFNKPAS 17343
Query 728 IGGSSCMSSSR---PSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQ 784
+ + S R P++ + NES+Q + + + S RSEST
Sbjct 17344 LQSTPDHSLERNLVPTLQKALNNESAQA-GQQIMLTCRISS-------------RSESTV 17389
Query 785 PLLDSEERPE 794
+ER E
Sbjct 17390 AWFKDDERIE 17399
Score = 42.5 bits (98), Expect = 0.025, Method: Composition-based stats.
Identities = 28/166 (17%), Positives = 50/166 (30%), Gaps = 7/166 (4%)
Query 49 VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCN--IL 106
+K + I N I + + I +T + T I S++ Q +
Sbjct 15711 TVKLRLSFSGRPQPEVIWIDNNGKVIEESRKMKIEKTVLNTVLT-INSIDSQDQGEFALK 15769
Query 107 TFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEW 164
+ ++ Y I I P P + +R W N+T+ E
Sbjct 15770 IKNRCGEDKYAIGIQVTDRPAAPGKPAVEDQNVDSVRLRWAAPTNDGGSPVRNYTV--EM 15827
Query 165 ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD 210
T K T + ++ V + V A+N G+
Sbjct 15828 CTEKGKTWTKAEVTKQAFITLFNLVPGESYRFRVRADNTFGQSEPS 15873
Score = 41.0 bits (94), Expect = 0.076, Method: Composition-based stats.
Identities = 24/162 (15%), Positives = 37/162 (23%), Gaps = 26/162 (16%)
Query 392 TNDRYLATLTVRNLVGKSDAAVLT--------------------IPACDFQATHPVMDLK 431
D T+T N GK +
Sbjct 17102 LEDEGTYTITAENEKGKIRQNTEVSVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPS 17161
Query 432 AFPKDNMLWVEWTTPRE-SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
K + + + P E Y +E + P +W T L +
Sbjct 17162 GASKTEQVTMAFDAPSEGPADSYEVE-----RRCPDQREWVSCGSTKSLELEIKGLTPNT 17216
Query 491 CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGK 532
Y+ V G G + + LK A + P K
Sbjct 17217 EYIFRVAGKNKQGLGEWSEMTSTLKTASVGQAPQFTISPQSK 17258
>sp|Q8BQC3|IGDC3_MOUSE Immunoglobulin superfamily DCC subclass
member 3 OS=Mus musculus OX=10090 GN=Igdcc3 PE=2 SV=1
Length=813
Score = 113 bits (282), Expect = 3e-24, Method: Composition-based stats.
Identities = 120/829 (14%), Positives = 241/829 (29%), Gaps = 128/829 (15%)
Query 22 GELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTI 81
G + + P + C + W+ N +P+ +T
Sbjct 49 GHSAELAFSVEPNDDIANPGQPIVLGC-------KVEGTPPVQVSWRKNGAELPEGTHTT 101
Query 82 INRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEK---------PKNL 132
+ S + + + + QN +G+ + + P+ +
Sbjct 102 LLANGS-LLIHHFRLEQGGSPSDEGDYECVAQNRFGLLVSRKARLQAATMSDFHVHPQAV 160
Query 133 S----------CIVNEGKKMRCEWDGGRETHLET---NFTLKSEWATHKFADCKAKRDTP 179
+ C ++ K W+ R ++T +TL + +A+
Sbjct 161 TGEEGGVARFQCQIHGLPKPLITWEKNRVP-IDTDDERYTL-LPKGVLQITGLRAEDSGI 218
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
C V+ + + +P V P L+V + L +
Sbjct 219 FHCVASNIASVRVSHGARLTV-----SGSGSGTYKEPTILVGPEN-LTLTVHQTAVLECV 272
Query 240 LK------LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK-PF 292
++W+ + I + D S V P
Sbjct 273 ATGNPRPIVSWSRLDGRP-------IGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPG 325
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
T R+R G+ +E RP+ + QG + W
Sbjct 326 T----RVR-RTAQGRLVVQAPAEFVQHPQSISRPAGT----TAMFTCQAQGEPPPHVTW- 375
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT-KLTVNLTNDRYLATLTVRNLVGKSDA 411
NG++L H++ N+T ++ D + N+ G S A
Sbjct 376 -----LKNGQVLG-------AGGHVRLKNNNSTLSISGVGPEDEAIYQCVAENIAGSSQA 423
Query 412 AVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCI 467
+ P +++A + V W+ P + + Y+L +D
Sbjct 424 SARLTVLWAEGLPGPPRNVRAVSVSSTEVRVSWSEPLAHTKEIIGYVLHIRKAADS--PK 481
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY--ADGPGSPESIKAYLKQAPPSKGPTV 525
++Q+ +L +L S Y + S ++ + L +AP P +
Sbjct 482 LEYQEAVSKSTFQHLVRDLEPSTAYSFYIKAYTPRGASLASVPTLASTLGEAPV--PPPL 539
Query 526 RTKKVGKNEAVLEWDQLPVDVQ-NGFIRNYTIFYRTIIGNETA--VNVDSSHTEYTLSSL 582
+ +G + L W P Q NG + +FYR + + + + + Y LS L
Sbjct 540 SVRLLGSSSLQLLWKPWPRLAQHNG---GFKLFYRPVSATSFTGPILLPGTVSSYNLSQL 596
Query 583 TSDTLYMVRMAAYTDEGGKD----------GPEFTFTTP--------KFAQGEIEAIVVP 624
T+Y V++ AY G + E T TP IV+
Sbjct 597 DPSTVYEVKLLAYNQHGDGNATVRFVSLKGASERTALTPPCDCRKEDVTNHTSTTGIVIG 656
Query 625 VCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYS 684
+ + + F +R + + +V + Q SP PR
Sbjct 657 IHIGVTCIIFCVLFLLFGQRGRVL--LCKDVEN-------QLSPPQGPRSQ--------- 698
Query 685 DGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSS 744
+ +++ + + D K +D + E++ S+ GS+ + P+
Sbjct 699 -RDPGILALNGLSRGEGGQLSRDEKPVDAKELEQLFPTAGSAAQPGSTPTDPAAPAPCEE 757
Query 745 DENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERP 793
+ Q + + P + PL + + +P
Sbjct 758 TQLSMVQLQGFNLVAGRTTEATSPCAGPGPVPAPQDIGPVPLSEGQTQP 806
Score = 102 bits (253), Expect = 9e-21, Method: Composition-based stats.
Identities = 74/442 (17%), Positives = 135/442 (31%), Gaps = 51/442 (12%)
Query 21 TGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWK--TNHFTIPKEQ 78
+G +P + PE+ + +H CV N IV + I E
Sbjct 244 SGTYKEPTILVGPENLTLTVHQTAVLECVATG--------NPRPIVSWSRLDGRPIGVEG 295
Query 79 YTIINRTASSVTFTDIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPE---KPKNLSC 134
++ ++ +D+ + C G + ++ P E P+++S
Sbjct 296 IQVLG--TGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISR 353
Query 135 IVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNI 194
C+ G H+ + A S + +
Sbjct 354 PAGTTAMFTCQAQGEPPPHVTWLKNGQVLGAGGHVRLKNNNSTLSISGVGPEDEAIYQCV 413
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
AEN G + + P PP N+ ++ S+ ++++W+ P + I
Sbjct 414 -----AENIAGSSQASARLTVLWAEGLPGPPRNVRAVSV--SSTEVRVSWSEPLAHTKEI 466
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
+ Y + R S + E + + V+DL+P T Y F I+ G S S
Sbjct 467 IGYVLHIRKAADSPKLEYQ-EAVSKSTFQHLVRDLEPSTAYSFYIKAYTPRGA---SLAS 522
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP-FEANGKILDYEVTLTRW 373
T + P P + S Q WK P + NG +++
Sbjct 523 VPTLASTLGEAPVPPPLSVRLLGSSSLQLL------WKPWPRLAQHNG---GFKLFYRPV 573
Query 374 KSHLQNYTV--NATKLTVNL----TNDRYLATLTVRNLVGKSDAAVLTIP---ACDFQAT 424
+ + T + NL + Y L N G +A V + A + A
Sbjct 574 SATSFTGPILLPGTVSSYNLSQLDPSTVYEVKLLAYNQHGDGNATVRFVSLKGASERTAL 633
Query 425 HPV-----MDLKAFPKDNMLWV 441
P D+ + +
Sbjct 634 TPPCDCRKEDVTNHTSTTGIVI 655
>sp|Q29116|TENA_PIG Tenascin OS=Sus scrofa OX=9823 GN=TNC PE=1
SV=1
Length=1746
Score = 113 bits (283), Expect = 3e-24, Method: Composition-based stats.
Identities = 80/487 (16%), Positives = 147/487 (30%), Gaps = 45/487 (9%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
PE NLS + W E ET FT++ + +
Sbjct 1075 PEI-GNLSVSDITPESFSLSWTA-TEGAFET-FTIEIIDSNRFLETMEYNISGAERTAHI 1131
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ V++ A G + + I+ + +P NL V S+ +L+WT
Sbjct 1132 SGLRPGNDFIVYLSGL-APG-IQTKPISATATTEAEPEV-DNLLV--SDATPDGFRLSWT 1186
Query 246 -NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ + +L + +D S+ ++ + + L+ TEY + +
Sbjct 1187 ADEGVFDSFVL------KIRDTKKQSEPLEITLLASERTRDITGLREATEYEIELYGISS 1240
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
S+ S I S + I + + W + +I
Sbjct 1241 ------GKRSQPVSAIATTAMGSPKEITFSDIT------ENSATVSWMVPTAQVESFRIT 1288
Query 365 DYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
+T + T T+L L YL ++ +S+ T+
Sbjct 1289 YVPITGGAPSVVTVDGTKTQTRLLRLLPGVEYLVSVIAVKGFEESEPVSGTLTT---ALD 1345
Query 425 HPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
P + A D+ W V Y++ + + + + Y
Sbjct 1346 GPSGLVTANITDSEALAMWQPAIAPVDHYVISY-----TGDRVPEITRTVSGNTVEYALT 1400
Query 485 NLAESKCYLITVTPVYADGPGSPESIKA-YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLP 543
NL + Y + + GP +I + + +V A+L W
Sbjct 1401 NLEPATEYTLRIFA--EKGPQKSSTITTKFTTDL--DSPRDLTATEVQSETALLTWRPPR 1456
Query 544 VDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ Y + Y ++ G V V T Y+LS L+ T Y R+ A
Sbjct 1457 AS-----VTGYLLVYESVDGTLKEVVVGPETTSYSLSGLSPSTHYTARIQALNGPLRSKM 1511
Query 604 PEFTFTT 610
+ FTT
Sbjct 1512 SQTVFTT 1518
Score = 109 bits (271), Expect = 9e-23, Method: Composition-based stats.
Identities = 69/380 (18%), Positives = 115/380 (30%), Gaps = 44/380 (12%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP +L V +E + L W + + +Y I Y ++S
Sbjct 625 PPKDLIV--TEVTEETVNLAW----DNEMRVTEYLIVYTPTHEDGLEM--QFRVPGDQTS 676
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
T+++L+P EY R+ + E+ K S S P+ + +
Sbjct 677 TTIRELEPGVEYFIRVFAILENKK------SIPVSARVATYLPTP------EGLKFKSIK 724
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWK--SHLQNYTVNATKLTVNLTNDRYLATL- 400
+V++ W L +I+ + + + T Y +L
Sbjct 725 ETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETTYRQTGLAPGQEYEISLH 784
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
V+N +T D + D+ D + W P + L + +
Sbjct 785 IVKNNTRGPGLKRVTTTRLDAPSQIEAKDVT----DTTALITWFKPLAEIDGIELTYGIK 840
Query 461 S-DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
D E Y GNL Y +++ AD +P P
Sbjct 841 DVPGDRTTIDLTHE----ENQYSIGNLKPDTEYEVSLISRRADMSSNPAKETFTTGLDAP 896
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI-IGNETAVNVDSS---HT 575
+R N LEW Y I Y I G+ V V S T
Sbjct 897 R---NLRRISQTDNSITLEWRNGKAAADT-----YRIKYAPISGGDHAEVEVPRSPQTTT 948
Query 576 EYTLSSLTSDTLYMVRMAAY 595
+ TL+ L T Y + ++A
Sbjct 949 KATLTGLRPGTEYGIGVSAV 968
Score = 108 bits (268), Expect = 2e-22, Method: Composition-based stats.
Identities = 85/586 (15%), Positives = 178/586 (30%), Gaps = 62/586 (11%)
Query 18 TESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKE 77
+ G + C +SP ++ + T + + V IV+ H +
Sbjct 610 ICNEGYSGEDCSQVSPPKDLIV--TEVTEE-TVNLAWDNEMRVTEYLIVYTPTHEDGLEM 666
Query 78 QYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVN 137
Q+ + S+ T ++ ++ + + ++++ ++ P P+ L
Sbjct 667 QFRVPGDQTST-TIREL-EPGVEYFIRVFAILENKKSIPVSARVATYLP-TPEGLKFKSI 723
Query 138 EGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
+ + EWD + ET + + P + E+
Sbjct 724 KETSVEVEWDP-LDIAFETWEIIFRNMNKEDEGEITKSLRRPETTYRQTGLAPGQEYEIS 782
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILK 256
+ + V + + P + + + ++++ TW P + I L
Sbjct 783 LHIVKNNTRGPG----LKRVTTTRLDAPSQIEAKDVTDTTALI--TWFKPLAEIDGIELT 836
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y I+ D +T D + +++ +LKP TEY + + D S+ ++E
Sbjct 837 YGIKDVPGDRTT------IDLTHEENQYSIGNLKPDTEYEVSLISRRADMS---SNPAKE 887
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL--DYEVTLTRWK 374
+ AP +I + ++ L W+ NGK Y +
Sbjct 888 TFTTGLD-----APRNLRRISQTDN----SITLEWR-------NGKAAADTYRIKYAPIS 931
Query 375 S------HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+ TK T+ + V + G ++ TI A
Sbjct 932 GGDHAEVEVPRSPQTTTKATLTGLRPGTEYGIGVSAVKGDKESDPATINAATDLDPPKDF 991
Query 429 DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
+ + ++ + W TP +Y L + P + + +Y+ L
Sbjct 992 RVSELKESSLTLL-WRTPLAKFDRYRLNY-----GLPSGQPVEVQLPRNATSYILRGLEP 1045
Query 489 SKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
+ Y I +T P +KA P G + + L W
Sbjct 1046 GQEYTILLTAEKGRHKSKPARVKASTA-GEPEIG-NLSVSDITPESFSLSWTAT-----E 1098
Query 549 GFIRNYTIFY--RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
G +TI N+ + +S L ++V +
Sbjct 1099 GAFETFTIEIIDSNRFLETMEYNISGAERTAHISGLRPGNDFIVYL 1144
Score = 106 bits (264), Expect = 7e-22, Method: Composition-based stats.
Identities = 63/502 (13%), Positives = 136/502 (27%), Gaps = 47/502 (9%)
Query 127 EKPKNLSCIVNEGKKMRCEW-DGGRE-THLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
+ P + W E +E + +K D + +
Sbjct 804 DAPSQIEAKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTHEENQY--SIG 861
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ EV + + A F + P NL + + + L W
Sbjct 862 NLKPD--TEYEVSLISRRADMSSNPAKETF----TTGLDAPRNLR--RISQTDNSITLEW 913
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
N + Y I+Y +++ + T + T+ L+P TEY + +K
Sbjct 914 RNGKAAAD---TYRIKYAPISGGDHAEVEVPRSPQTTTKATLTGLRPGTEYGIGVSAVKG 970
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
D +E+ T P +++ ++ L+W+T
Sbjct 971 D---------KESDPATINAATDLDPPKDFRV---SELKESSLTLLWRTPLAKFDR---- 1014
Query 365 DYEVTLTRWKSHLQNY--TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
Y + NAT + T+ + G+ + + A
Sbjct 1015 -YRLNYGLPSGQPVEVQLPRNATSYILRGLEPGQEYTILLTAEKGRHKSKPARVKASTAG 1073
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
+ + WT + + + +E + D + + RT
Sbjct 1074 EPEIGNLSVSDITPESFSLSWTATEGAFETFTIE---IIDSNRFLETMEYNISGAERTAH 1130
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
L +++ ++ + P S A + P + + + L W
Sbjct 1131 ISGLRPGNDFIVYLSGLAPGIQTKPISATATTEAEP--EVDNLLVSDATPDGFRLSW--- 1185
Query 543 PVDVQNGFIRNYTIFYRT--IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
G ++ + R + + +S ++ L T Y + + + G
Sbjct 1186 --TADEGVFDSFVLKIRDTKKQSEPLEITLLASERTRDITGLREATEYEIELYGISS-GK 1242
Query 601 KDGPEFTFTTPKFAQGEIEAIV 622
+ P T +
Sbjct 1243 RSQPVSAIATTAMGSPKEITFS 1264
Score = 68.3 bits (165), Expect = 3e-10, Method: Composition-based stats.
Identities = 39/218 (18%), Positives = 70/218 (32%), Gaps = 14/218 (6%)
Query 417 PACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
D P DL + + + W V +Y++ + + + + G
Sbjct 616 SGEDCSQVSPPKDLIVTEVTEETVNLAWD-NEMRVTEYLIVYTPTHEDGLEMQF--RVPG 672
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
T +R L Y I V + + P S + P ++ K + +
Sbjct 673 DQTSTTIRE-LEPGVEYFIRVFAILENKKSIPVSARVATYLPTPEG---LKFKSIKETSV 728
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN--VDSSHTEYTLSSLTSDTLYMVRMA 593
+EWD L + + I IF +E + + T Y + L Y + +
Sbjct 729 EVEWDPLDIAFETWEI----IFRNMNKEDEGEITKSLRRPETTYRQTGLAPGQEYEISLH 784
Query 594 AYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLL 631
+ G + TT A +IEA V A +
Sbjct 785 IVKNNTRGPGLKRVTTTRLDAPSQIEAKDVTDTTALIT 822
>sp|Q8IVU1|IGDC3_HUMAN Immunoglobulin superfamily DCC subclass
member 3 OS=Homo sapiens OX=9606 GN=IGDCC3 PE=2 SV=2
Length=814
Score = 113 bits (281), Expect = 4e-24, Method: Composition-based stats.
Identities = 75/444 (17%), Positives = 139/444 (31%), Gaps = 68/444 (15%)
Query 21 TGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWK--TNHFTIPKEQ 78
+G +P + PE+ + +H CV N IV + I E
Sbjct 232 SGAYKEPAILVGPENLTLTVHQTAVLECVATG--------NPRPIVSWSRLDGRPIGVEG 283
Query 79 YTIINRTASSVTFTDIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPE---KPKNLSC 134
++ ++ +D+ + C G + ++ P E P+++S
Sbjct 284 IQVLG--TGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISR 341
Query 135 IVNEGKKMRC----------EW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
C W G+ + LK+ +T + + + C
Sbjct 342 PAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCV 401
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
AEN+ G + + P PP N+ ++ S+ ++++
Sbjct 402 ----------------AENSAGSSQASARLTVLWAEGLPGPPRNVRAVSV--SSTEVRVS 443
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
W+ P + I+ Y + R + E + + V DL+P T Y F I+
Sbjct 444 WSEPLANTKEIIGYVLHIRKAADPPELEYQ-EAVSKSTFQHLVSDLEPSTAYSFYIKAYT 502
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP-FEANGK 362
G S S T + P+ P + G ++QL+W+ P + G
Sbjct 503 PRGA---SSASVPTLASTLGEAPAPPPLSVRVL------GSSSLQLLWEPWPRLAQHEG- 552
Query 363 ILDYEVTLTRWKSHLQNYTV--NATKLTVNL----TNDRYLATLTVRNLVGKSDAAVLTI 416
+++ + T + NL Y L N G +A V +
Sbjct 553 --GFKLFYRPASKTSFTGPILLPGTVSSYNLSQLDPTAVYEVKLLAYNQHGDGNATVRFV 610
Query 417 P---ACDFQATHPVMDLKAFPKDN 437
A + A P D + N
Sbjct 611 SLRGASERTALSPPCDCRKEEAAN 634
Score = 74.5 bits (181), Expect = 3e-12, Method: Composition-based stats.
Identities = 75/541 (14%), Positives = 160/541 (30%), Gaps = 78/541 (14%)
Query 30 YISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIP--KEQYTIINRTAS 87
++ P++ V + C + + I W+ N I E+YT++ +
Sbjct 142 HVHPQATVGEEGGVARFQCQIH-------GLPKPLITWEKNRVPIDTDNERYTLLPKGVL 194
Query 88 SVTF-------------TDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSC 134
+T ++IAS+ I + G I+ G P+NL+
Sbjct 195 QITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEPAILVG-----PENLTL 249
Query 135 IVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNI 194
V++ + C T S + + + TV
Sbjct 250 TVHQTAVLEC-----VATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSG- 303
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
V+V A N G + ++ P V + + +S P+ + +
Sbjct 304 -VYVCAANRPG----TRVRRTAQGRLVVQAPAEF-VQHPQSISR--------PAGTTAMF 349
Query 255 LKYNIQYRTKDASTWSQIP-------PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
Q TW + + S+ T+ + P E +++ G
Sbjct 350 T-CQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGS 408
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
S S + + E P P + S T V++ W +I+ Y
Sbjct 409 ---SQASARLTVLWAEGLP-GPPRNVRAVSVSST----EVRVSWSEPLANTK--EIIGYV 458
Query 368 VTLTRWKSHLQ-------NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
+ + + + + + ++ + Y + G S A+V T+ +
Sbjct 459 LHIRKAADPPELEYQEAVSKSTFQHLVSDLEPSTAYSFYIKAYTPRGASSASVPTLASTL 518
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQE-DGTVHR 479
+A P + L + W P + ++ + + A +
Sbjct 519 GEAPAPPPLSVRVLGSSSLQLLWE-PWPRLAQHEGGFKLFYRPASKTSFTGPILLPGTVS 577
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSP----ESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
+Y L + Y + + G G+ S++ ++ S R ++ +
Sbjct 578 SYNLSQLDPTAVYEVKLLAYNQHGDGNATVRFVSLRGASERTALSPPCDCRKEEAANQTS 637
Query 536 V 536
Sbjct 638 T 638
Score = 69.1 bits (167), Expect = 1e-10, Method: Composition-based stats.
Identities = 45/287 (16%), Positives = 79/287 (28%), Gaps = 27/287 (9%)
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGP-GSPESIKAYLKQAPPSKGPTVRTKKVGKNE 534
+ T + + + G + + + P VR V E
Sbjct 380 NNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPRNVRAVSVSSTE 439
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYR-TIIGNETAVN--VDSSHTEYTLSSLTSDTLYMVR 591
+ W + I Y + R E V S ++ +S L T Y
Sbjct 440 VRVSWSE--PLANTKEIIGYVLHIRKAADPPELEYQEAVSKSTFQHLVSDLEPSTAYSFY 497
Query 592 MAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHI 651
+ AYT G + + P A EA P L+ + + L+ +
Sbjct 498 IKAYTPRGA-----SSASVPTLASTLGEAP-APPPLSVRVLGSSSL-------QLLWEP- 543
Query 652 WPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSL 711
WP + ++ + P + + VS + D E
Sbjct 544 WPRL---AQHEGGFKLFYRPASKTSFTGPILL----PGTVSSYNLSQLDPTAVYEVKLLA 596
Query 712 DLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQ 758
+ T S G S + S P +E + +T+ V
Sbjct 597 YNQHGDGNATVRFVSLRGASERTALSPPCDCRKEEAANQTSTTGIVI 643
>sp|Q18245|YC27B_CAEEL Ig-like and fibronectin type-III domain-containing
protein C27B7.7 OS=Caenorhabditis elegans OX=6239
GN=C27B7.7 PE=1 SV=2
Length=1456
Score = 113 bits (282), Expect = 4e-24, Method: Composition-based stats.
Identities = 82/523 (16%), Positives = 160/523 (31%), Gaps = 56/523 (11%)
Query 128 KPKNLSCIVNEGKKMRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+P +++C V K W G + ++++F F + + + T
Sbjct 248 EPLSITCTVKSVSKASVLWKVNGIKVSVDSSFYTVVTSVHEDFIESTIRAKSRTRSA--- 304
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ A N G + + + + K +PP ++++ ++W
Sbjct 305 --------KFTCLATNDAGDSSKE---VNVIIKGPGSPPSEITLVAE---KRGYTISWKP 350
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF--RIRCMKE 304
PS + I KY + + S D + + TE F R++ E
Sbjct 351 PSHPNGKITKYVVYHTLNREDPLSDWRKIDLDGSEKMVRIIM---DTEESFYGRVQAATE 407
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
G G SD S + + ++Q + P + I
Sbjct 408 LGPGIISDIVAMERDTQPISVESDLFGVSATTMVVNPRETLSIQCTARGKPRPSISVAIS 467
Query 365 DYEVTLTRWKSHLQNYTVNATKLTVN-----LTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
D + ++ V+ +N G S+ + + +
Sbjct 468 DRKNASQVEVDVWSRLQATSSAGIVSAVHNFSVLTSKFVHCRAKNSAG-SNYSTMELKVD 526
Query 420 DFQATHPVMDLKAFPKDNMLWV--EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
+ + + + L V P + YI+ V +D + W Q +
Sbjct 527 KPGDAPTQIQVLSVNALDALVVWHSPQFPNSPITSYIV--LVSNDDKEDKSTWLQYESNA 584
Query 478 HRTYL------RGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGP-TVRTKK 529
T + GNL +S Y + V A G G S+ ++ P P ++
Sbjct 585 KETQINRMLLPTGNLEKSTEYFVCVRAKNAAGIGPTSSLISFITLNGGPDSPPDNLKVLI 644
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-------NETAVNVDSSHTEYTL--- 579
N+ ++ W+ + Y I+Y + N V ++++ T Y
Sbjct 645 NEANQVIVYWNTPNSTT---EVTGYLIYYTRDLSLSNDDYKNWQFVEMNNNSTRYKFDLS 701
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIV 622
L T Y VR++ DGP + A E+
Sbjct 702 VGLKPKTFYRVRISGKNS--HADGPASEVVEFETAYSEVPIPT 742
Score = 101 bits (251), Expect = 2e-20, Method: Composition-based stats.
Identities = 76/438 (17%), Positives = 139/438 (32%), Gaps = 52/438 (12%)
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKS- 162
N G + IT+ G P P NL ++NE ++ W+ T T + +
Sbjct 613 NAAGIGPTSSLISFITLNGG-PDSPPDNLKVLINEANQVIVYWNTPNSTTEVTGYLIYYT 671
Query 163 ---EWATHKFADCKAKRDTPTSCTVDYSTVY----FVNIEVWVEAENALGKVT-SDHINF 214
+ + + + S + V + +N+ S+ + F
Sbjct 672 RDLSLSNDDYKNWQFVEMNNNSTRYKFDLSVGLKPKTFYRVRISGKNSHADGPASEVVEF 731
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTW-TNPSIKSVIILKYNIQYRTKD---ASTWS 270
+ Y P P +L ++ + +K +P S + +Y I D + W
Sbjct 732 ETAYSEVPI-PTDLKTEVLDDNTIHIKFNAVRDPDDHSKALGEYRIDLAATDDVLHALWK 790
Query 271 QIPPEDTASTRSSFTVQ------DLKPFTEYVFRIRCMKED----GKGYWSDWSEEASG- 319
QI P+ S V ++ Y ++ ++ W G
Sbjct 791 QIEPKSIKIDEISSMVDVEIDGDSVEKNQMYWVKVTARLDNPSWGMHSSKPRWFRTGHGK 850
Query 320 ----ITYEDRP--SKAPSFWYKIDPSHTQ-GYRTVQLVWKTLPPFEANGKILDYEVTLTR 372
+T E P K P+ + ++ + T G + W+ + NG
Sbjct 851 LMTSVTLEGAPLIEKEPNLFEELSVTCTGMGSPAPIITWEWMNKSIENGT--------EG 902
Query 373 WKSHLQNYTVNA--TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
W +K+T N + T N G S A+V +P ++
Sbjct 903 WNILNIQIDDTTVVSKITRNNIRESGDLTCLANNNEGSSSASVE---IRVLGPGNPPENI 959
Query 431 KAFPKDNMLWVEWT---TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
N + V W P + KYI+ + + ++DW + + TY+
Sbjct 960 ILTAYRNQINVTWQESTLPNGDIMKYIVYYSENENDD--LSDWNKFETAELETYV-ETFG 1016
Query 488 ESKCYLITVTPVYADGPG 505
+ I V V GPG
Sbjct 1017 PHTKHFIRVQAVSDRGPG 1034
Score = 99.2 bits (245), Expect = 1e-19, Method: Composition-based stats.
Identities = 96/614 (16%), Positives = 192/614 (31%), Gaps = 87/614 (14%)
Query 49 VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTF 108
L +C + V ++ + + + +R ++ + +++++
Sbjct 447 TLSIQCTARGKPRPSISVAISDRKNASQVEVDVWSRLQATSSAGIVSAVHNFSVLTSKFV 506
Query 109 GQLEQNVYGI-----TIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTL-- 160
+N G + P + P + + W + + T++ +
Sbjct 507 HCRAKNSAGSNYSTMELKVDKPGDAPTQIQVLSVNALDALVVWHSPQFPNSPITSYIVLV 566
Query 161 ----KSEWATHKFADCKAKRDTPTS-CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFD 215
K + +T + AK + V V A+NA G + +
Sbjct 567 SNDDKEDKSTWLQYESNAKETQINRMLLPTGNLEKSTEYFVCVRAKNAAGIGPTSSLISF 626
Query 216 PVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY------RTKDAST 268
P+ PP NL V+ +E + + W P+ + + Y I Y D
Sbjct 627 ITLNGGPDSPPDNLKVLINEAN--QVIVYWNTPNSTTE-VTGYLIYYTRDLSLSNDDYKN 683
Query 269 WSQIPPEDTASTRSSFTVQ-DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
W + + STR F + LKP T Y RI G S+ E + + P+
Sbjct 684 WQFVEMNNN-STRYKFDLSVGLKPKTFYRVRISGKNSHADGPASEVVEFETAYSEVPIPT 742
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ--------- 378
+ + H + V+ +A G+ Y + L L
Sbjct 743 DLKTEVLDDNTIH-IKFNAVR---DPDDHSKALGE---YRIDLAATDDVLHALWKQIEPK 795
Query 379 --NYTVNATKLTVNLTNDR------YLATLTVR---NLVG--KSDA-----------AVL 414
++ + V + D Y +T R G S +
Sbjct 796 SIKIDEISSMVDVEIDGDSVEKNQMYWVKVTARLDNPSWGMHSSKPRWFRTGHGKLMTSV 855
Query 415 TIPACDFQATHPVMDLKAFPKDNML-----WVEWTTPRESVKKYILEWCVLSDKAPCITD 469
T+ P + + + + W +S++ W I +
Sbjct 856 TLEGAPLIEKEPNLFEELSVTCTGMGSPAPIITWEWMNKSIENGTEGW--------NILN 907
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKK 529
Q +D TV R N+ ES +T +G S S++ + P P
Sbjct 908 IQIDDTTVVSKITRNNIRESG--DLTCLANNNEGS-SSASVEIRV--LGPGNPPENIILT 962
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA--VNVDSSHTEYTLSSLTSDTL 587
+N+ + W + + NG I Y ++Y ++ + +++ E + + T
Sbjct 963 AYRNQINVTWQE--STLPNGDIMKYIVYYSENENDDLSDWNKFETAELETYVETFGPHTK 1020
Query 588 YMVRMAAYTDEGGK 601
+ +R+ A +D G
Sbjct 1021 HFIRVQAVSDRGPG 1034
Score = 90.3 bits (222), Expect = 5e-17, Method: Composition-based stats.
Identities = 63/443 (14%), Positives = 126/443 (28%), Gaps = 26/443 (6%)
Query 107 TFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWAT 166
F Q + + NL +V + G T + +T S
Sbjct 16 CFDSAGQINDDSPLFISTSIDNSMNLKILVEKKPYFT-----GSVTGYKLYYTNDSSQTN 70
Query 167 HKFADCKAKRDTPTSCTVDY-----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK 221
++ + + ++ V A V S + +
Sbjct 71 EEYEKWMHQEALSNQNSYNFVIDANKHEIVSGDVYRVRATVFFNNVESVPTGVISINTRQ 130
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P L V +S + +++ + I Y + Y+ +A W + + +
Sbjct 131 SIPKAPLIVNTKILYNSSVLISFVPADDVN-AIENYTLMYKQMEAEEWKSLNFKSDFDGK 189
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+ L P Y +I +G S+ + + T P Y DP T
Sbjct 190 --VLLDGLIPNHTYEIKIFVTGGIVQGTPSNLATFTTNSTALALVKTEPDEEYTADP-QT 246
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVT----LTRWKSHLQNYTVNATKLTVNLTNDRYL 397
++ K++ K+ +V+ + + + +T + T
Sbjct 247 NEPLSITCTVKSVSKASVLWKVNGIKVSVDSSFYTVVTSVHEDFIESTIRAKSRTRSA-K 305
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
T N G S V I P ++ + + W P I ++
Sbjct 306 FTCLATNDAGDSSKEVNVI---IKGPGSPPSEITLVAEKRGYTISWKPPSHP-NGKITKY 361
Query 458 CVLS--DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
V ++ ++DW++ D +R + + + V GPG I A +
Sbjct 362 VVYHTLNREDPLSDWRKIDLDGSEKMVRIIMDTEESFYGRVQAATELGPGIISDIVAMER 421
Query 516 QAPPSKGPTVRTKKVGKNEAVLE 538
P + V V+
Sbjct 422 DTQPISVES-DLFGVSATTMVVN 443
Score = 89.9 bits (221), Expect = 7e-17, Method: Composition-based stats.
Identities = 73/437 (17%), Positives = 141/437 (32%), Gaps = 60/437 (14%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A N G ++ + NPP N+ + + +TW ++ + I+KY +
Sbjct 934 ANNNEGSSSAS---VEIRVLGPGNPPENIILTAYRN---QINVTWQESTLPNGDIMKYIV 987
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW----SE 315
Y + S +TA + P T++ R++ + + G G S+ S+
Sbjct 988 YYSENENDDLSDWNKFETAELETYVETFG--PHTKHFIRVQAVSDRGPGIISNVLSCISD 1045
Query 316 EASGIT-YEDRPSKAPSFWYKIDP-----SHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
E S F + + G +L ++ E N
Sbjct 1046 VLYETIHLEIVASNILDFEAEPNQNVEIRCKGTGKPQPELFYQFANETEQN--------F 1097
Query 370 LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMD 429
+ + + + A ++ N R T+T R + + + P
Sbjct 1098 VEVETNDMDLFEAKAPEI-----NSRRNVTVTCRASNKYENVTISKVIIIKRPGEAPTNI 1152
Query 430 LKAFPK--DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
+F + D+ L++ W P E+ LE+ + T + L N++
Sbjct 1153 SWSFEEEYDSTLYINWN-PIENANGEKLEYNLYLSN--YKTKVSGPPVKIPDIPLDVNIS 1209
Query 488 ESKCYLITVTPVYADGPG-SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDV 546
+ V+ G G I P P + + ++ + W + +
Sbjct 1210 ------LRVSAENEYGEGEKTFPIWIPTPNGGPKTAPILSSLHAQDSKVYIFWVE--PRL 1261
Query 547 QNGFIRNYTIFYR----------TIIGNETAVNVDSSHTEYTLS---SLTSDTLYMVRMA 593
NG I+NYTI+ + +I S+ T + L + Y ++M
Sbjct 1262 PNGEIQNYTIYIQKENESENEEHSIDKEWKKFIYGSNITHVIIGVDDGLEENERYQMKMT 1321
Query 594 AYTDEGGKDGPEFTFTT 610
A +GPE T
Sbjct 1322 ATN--QRHEGPETKVYT 1336
Score = 81.4 bits (199), Expect = 3e-14, Method: Composition-based stats.
Identities = 99/716 (14%), Positives = 196/716 (27%), Gaps = 83/716 (12%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYT-IINRTASSVTFTDIASLNIQLTCNILTFGQLEQN 114
D N Y W + Y +I+ + D+ + + N +
Sbjct 65 DSSQTNEEYEKWMHQEALSNQNSYNFVIDANKHEIVSGDVYRVRATVFFNNVESVPTGVI 124
Query 115 VYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA 174
P+ P ++ + + + + + N+TL + +
Sbjct 125 SINTRQSI---PKAPLIVNTKILYNSSVLISFVPADDVNAIENYTLMYKQMEAEEWKSLN 181
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
+ + + E+ + + + T ++ + E
Sbjct 182 FKSDFDGKVLLDGLIPNHTYEIKIFVTGGIVQGTPSNLATFTTNSTAL---ALVKTEPDE 238
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
E ++ +P + + ++ +K + W + + + V +
Sbjct 239 EYTA-------DPQTNEPLSITCTVKSVSKASVLWKVNGIKVSVDSSFYTVVTSVHEDFI 291
Query 295 YVFRIRCMKEDGKGYW--------SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
IR + D S+E + I P PS + + R
Sbjct 292 -ESTIRAKSRTRSAKFTCLATNDAGDSSKEVNVII--KGPGSPPS-----EITLVAEKRG 343
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWK----SHLQNYTVNATKLTVNL---TNDRYLAT 399
+ WK PP NGKI Y V T + S + ++ ++ V + T + +
Sbjct 344 YTISWK--PPSHPNGKITKYVVYHTLNREDPLSDWRKIDLDGSEKMVRIIMDTEESFYGR 401
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT----------PRES 449
+ +G + + D Q DL M+ T PR S
Sbjct 402 VQAATELGPGIISDIVAMERDTQPISVESDLFGVSATTMVVNPRETLSIQCTARGKPRPS 461
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES 509
+ I + S + W + T + S V + GS S
Sbjct 462 ISVAISDRKNASQVEVDV--WSRLQATSSAGIVSAVHNFSVLTSKFVHCRAKNSAGSNYS 519
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
P ++ V +A++ W N I +Y + + +
Sbjct 520 TMELKVDKPGDAPTQIQVLSVNALDALVVWHS--PQFPNSPITSYIVLVSNDDKEDKSTW 577
Query 570 VDSSHTE---------YTLSSLTSDTLYMVRMAAYTDEGGKDGPEF-TFTTPKFAQ---- 615
+ +L T Y V + A G +F T
Sbjct 578 LQYESNAKETQINRMLLPTGNLEKSTEYFVCVRAKNAAGIGPTSSLISFITLNGGPDSPP 637
Query 616 -------GEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKK---HIWPNVPDPSKSHIAQ 665
E ++V T + G L + + + W V + S +
Sbjct 638 DNLKVLINEANQVIVYWNTPNSTTEVTGYLIYYTRDLSLSNDDYKNWQFVEMNNNSTRYK 697
Query 666 WSPHTPPRHNFN-----SKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKK 716
+ + S ++DG ++V E A + P P DLK+ L
Sbjct 698 FDLSVGLKPKTFYRVRISGKNSHADGPASEVVEFET-AYSEVPIPTDLKTEVLDDN 752
Score = 64.5 bits (155), Expect = 5e-09, Method: Composition-based stats.
Identities = 60/350 (17%), Positives = 106/350 (30%), Gaps = 47/350 (13%)
Query 193 NIEVWVEAENALGKVTSDHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKS 251
N+ V A N VT + +P P N+S EE S L + W +
Sbjct 1120 NVTVTCRASNKYENVTISKVII----IKRPGEAPTNISWSFEEEYDSTLYINWNPIENAN 1175
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
L+YN+ + T + + D+ R+ E G+G
Sbjct 1176 GEKLEYNL-----------YLSNYKTKVSGPPVKIPDIPLDVNISLRVSAENEYGEG--- 1221
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
E + + P+ P + H Q + V + W + P NG+I +Y + +
Sbjct 1222 ----EKTFPIWIPTPNGGPKTAPILSSLHAQDSK-VYIFW--VEPRLPNGEIQNYTIYIQ 1274
Query 372 RWKSHLQN------------YTVNATKLTVNL-----TNDRYLATLTVRNLVGKSDAA-V 413
+ Y N T + + + N+RY +T N + V
Sbjct 1275 KENESENEEHSIDKEWKKFIYGSNITHVIIGVDDGLEENERYQMKMTATNQRHEGPETKV 1334
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQE 473
T F + + A ++ ++V KY + + + E
Sbjct 1335 YTFDLISFDENDVIDNFTAIVINSTVFV--EVGNPIYTKYNIYIREDGNNQTVKHEIDVE 1392
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
G L + Y I ++ + P + PS P
Sbjct 1393 SGKTT-FEFPFQLDHTLSYTIKMSGMKLGRESPPSEEIDLEFISSPSPTP 1441
>sp|Q07496|EPHA4_CHICK Ephrin type-A receptor 4 OS=Gallus gallus
OX=9031 GN=EPHA4 PE=1 SV=2
Length=986
Score = 112 bits (280), Expect = 5e-24, Method: Composition-based stats.
Identities = 49/241 (20%), Positives = 78/241 (32%), Gaps = 23/241 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTL--------KSEWATHKFAD 171
PP P+NL VNE + EW GGR+
Sbjct 328 PPSAPQNLISNVNE-TSVNLEWSAPQNKGGRDDISYNVVCKRCGAGEPSHCRSCGSGVHF 386
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSV 230
+ T+ + N V A N + K S P +++
Sbjct 387 SPQQNGLKTTKVSITDLLAHTNYTFEVWAVNGVSKHNPSQDQAVSVTVTTNQAAPSPIAL 446
Query 231 INSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
I ++E++ + L W P + +IL+Y ++Y KD ++ + + ++ L
Sbjct 447 IQAKEITRHSVALAWLEPDRPNGVILEYEVKYYEKD---QNERSYRIVKTASRNTDIKGL 503
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
P T YVF +R G G +S E T PS +V L
Sbjct 504 NPLTSYVFHVRARTAAGYGDFSGPFE----FTTNTVPSPIIGDGTNPTVLLVSVAGSVVL 559
Query 350 V 350
V
Sbjct 560 V 560
Score = 110 bits (274), Expect = 2e-23, Method: Composition-based stats.
Identities = 58/325 (18%), Positives = 104/325 (32%), Gaps = 49/325 (15%)
Query 351 WKTLPPFEANGKILDYE-----VTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNL 405
++ KI Y+ V + H + +T T + N
Sbjct 266 YEERNGECQACKIGYYKALSTDVACAKCPPHSYSIWEGSTSCTCDRG------FFRAEND 319
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDK-- 463
+L + + + +EW+ P+ + + + V+ +
Sbjct 320 AASMPCTR---------PPSAPQNLISNVNETSVNLEWSAPQNKGGRDDISYNVVCKRCG 370
Query 464 ----------APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE----- 508
+ Q++G +L Y V V +P
Sbjct 371 AGEPSHCRSCGSGVHFSPQQNGLKTTKVSITDLLAHTNYTFEVWAVNGVSKHNPSQDQAV 430
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA- 567
S+ QA PS ++ K++ ++ L W + D NG I Y + Y NE +
Sbjct 431 SVTVTTNQAAPSPIALIQAKEITRHSVALAWLE--PDRPNGVILEYEVKYYEKDQNERSY 488
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD--GPEFTFTT-----PKFAQG-EIE 619
V ++ + L T Y+ + A T G D GP F FTT P G
Sbjct 489 RIVKTASRNTDIKGLNPLTSYVFHVRARTAAGYGDFSGP-FEFTTNTVPSPIIGDGTNPT 547
Query 620 AIVVPVCLAFLLTTLLGVLFCFNKR 644
++V V + +L +L F ++R
Sbjct 548 VLLVSVAGSVVLVVILIAAFVISRR 572
>sp|H2KZ60|RIG6_CAEEL Contactin rig-6 OS=Caenorhabditis elegans
OX=6239 GN=rig-6 PE=1 SV=1
Length=1196
Score = 112 bits (279), Expect = 7e-24, Method: Composition-based stats.
Identities = 117/663 (18%), Positives = 203/663 (31%), Gaps = 131/663 (20%)
Query 31 ISPESPVVQ-----LHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRT 85
+ P + + + S + C+ F + + + Q I
Sbjct 540 VFPPNAMSRKVFAAFGSTVSIPCI--------FEASPRFHGKWADAGGSKLPQKGRIRDE 591
Query 86 ASSVTFTDIASLNIQLT-CNILT-FGQLEQNVYGITIISGLPP-------EKPKNLSCIV 136
++ + + L C G+ V I+ P E+ N+SC V
Sbjct 592 EGVISIEKVLHEDAGLFFCTAHNKLGKAHAQV--QLIVVNKPSIKTNFLDEETVNMSCEV 649
Query 137 NEGKKMRCE-----------W----DGGRE-THLETNFTLKSEWATHKFADCKAKRDTPT 180
++ CE W +E L++ K + K + P
Sbjct 650 ----ELTCENSAECPEALFEWKINDRPAKEYPSLKSKVHEKKSGHKGRHLKQKVDLEVPK 705
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE---LS 237
S F ++ G + + V K + P L+V +E
Sbjct 706 SLAGSRQIGRFACSSLY-------GGSS------EFVTKPQLPSPIALTVEQMDEDGKKK 752
Query 238 SILKLTWT-NPSIKSV-----IILKYNIQYRTKDASTWSQIPPEDT-ASTRSSFTVQDLK 290
+ +L W P + + Y ++ RT+ W + + S TV++L
Sbjct 753 KMFRLRWRLPPQHRDTRDHSPKVEGYLVELRTRKNRKWRAAERQLVGNMEKDSITVENLL 812
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF--WYKIDPSHTQGYRTVQ 348
P TEY FR+R ++ G S S+ T PS+ W +D +T+
Sbjct 813 PNTEYQFRVRSVESAAIGEPSIPSD--WVKTAPGAPSETIDNLKWRSLD------SQTLL 864
Query 349 LVWKTLP-PFEANGKILDYEVTLTRWKSHLQ------------------NYTVNATKLTV 389
+ W+ + E++G L Y V+ + + L +
Sbjct 865 VEWQPIEIGQESSGDNLRYRVSWSEATVGKNATDDMKLSNQDDDFENHLDSDQPQAILKL 924
Query 390 NLTNDRYLATLTVR--NLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM--LWVEWTT 445
N T + L VR N G TI + + L N + + WT
Sbjct 925 NTTEGCRMVVLAVRPVNDQGNGSVGTDTIAFLNSHGELKKVSLHNVKPINASHVNISWTW 984
Query 446 PRESVK--KYILEWCVLSDKAPCITDWQQEDGTVHRTYLR---GNLAESKCYLITVTPVY 500
S K+ ++ ++ + TV + G L Y + +
Sbjct 985 DNTSDCDTKHAVQITCINLSGS------EISATVASDRIFWMLGGLEAETAYDCDLKAID 1038
Query 501 ADGPGSPESIKAY--LKQAPPSKGP---TVRTKKVGKN-EAVLEWDQL----PVDVQNGF 550
G P S K KQ PPS+ P + K++ +LEW + P +NG
Sbjct 1039 NHGSFGPASKKFRIHTKQHPPSETPLIGKLMMKQMKDTYTTILEWSSIELQKPNRTENGC 1098
Query 551 IRNYTIFYRTIIGNETAVNVDSSHTEY--------TLSSLTSDTLYMVRMAAYTDEGGKD 602
Y IF A+ +D L L +Y +++A Y G
Sbjct 1099 --GYKIFIYISETATEAIELDMPLQRLSDRRNPSARLDGLKLMYMYTIKVAGYNPGGIGP 1156
Query 603 GPE 605
E
Sbjct 1157 ISE 1159
>sp|B1AUH1|PTPRU_MOUSE Receptor-type tyrosine-protein phosphatase
U OS=Mus musculus OX=10090 GN=Ptpru PE=1 SV=1
Length=1446
Score = 112 bits (280), Expect = 8e-24, Method: Composition-based stats.
Identities = 61/365 (17%), Positives = 114/365 (31%), Gaps = 39/365 (11%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
+ + K P P ++ + I++L TN I I++ I+YR W+++
Sbjct 279 ELIVKEPPTPIAPPQLLRAGPTYLIIQLN-TNSIIGDGPIVRKEIEYRMARGP-WAEVHA 336
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
+ ++ + L P TEY + + G G T P++AP
Sbjct 337 VNL----QTYKLWHLDPDTEYEISVL-LTRPGDGGTGRPGPPLISRTKCAEPTRAP---- 387
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN--------ATK 386
K R + L W+ L + N T+ A++
Sbjct 388 KGLAFAEIQARQLTLQWEPLGYNVTRCHTYAVSLCYRYTLGGSHNQTIRECVKMERGASR 447
Query 387 LTV--NLTNDRYLATLTVRNLVGKSDAAVLTIPAC-DFQATHPVMDLKAFPKDNMLWVEW 443
T+ L L + N G+ + +T D L P ++M++++W
Sbjct 448 YTIKNLLPFRNIHVRLILTNPEGRKEGKEVTFQTDEDVPGGIAAESLTFTPLEDMIFLKW 507
Query 444 TTPRESVKKYILEWCVLSDKAPCITDWQQEDG--------TVHRTYLRGNLAESKCYLIT 495
P+E I ++ + G ++ NL YL +
Sbjct 508 EEPQEP-NGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSNLHPGTTYLFS 566
Query 496 VTPVYADGPGSPESIKAYLKQAPPS----KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
V + G G + + PS P+ + +L P + I
Sbjct 567 VRARTSKGFGQAALTEITTNISAPSFDYADMPSPLGESENTITVLLR----PAQGRGAPI 622
Query 552 RNYTI 556
Y +
Sbjct 623 SVYQV 627
Score = 88.4 bits (217), Expect = 2e-16, Method: Composition-based stats.
Identities = 67/357 (19%), Positives = 119/357 (33%), Gaps = 49/357 (14%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGG--RETHLET-------NFTLKSEWATHKFADCKAK 175
P PK L+ + +++ +W+ T T +TL K +
Sbjct 383 PTRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYAVSLCYRYTLGGSHNQTIRECVKME 442
Query 176 RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
R + F NI V + N G+ + F V P ++ +
Sbjct 443 RGASRYTIKNLLP--FRNIHVRLILTNPEGRKEGKEVTFQTDEDV----PGGIAAESLTF 496
Query 236 LS--SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP-----EDTASTRSSFTVQD 288
++ L W P + +I +Y I Y++ ++S + P + +
Sbjct 497 TPLEDMIFLKWEEPQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYHVFSN 556
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS-HTQGYRTV 347
L P T Y+F +R G G + +T APSF Y PS + T+
Sbjct 557 LHPGTTYLFSVRARTSKGFGQ--------AALTEITTNISAPSFDYADMPSPLGESENTI 608
Query 348 QLVWKTLPPFEANG-KILDYEVTLTRWKSHLQNYTVNAT-KLTVNLTNDRYLATLTVRNL 405
++ L P + G I Y+V + + A +V LT + LA
Sbjct 609 TVL---LRPAQGRGAPISVYQVVVEEERPRRLRREPGAQDCFSVPLTFETALAR------ 659
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE-WTTPRESVKKYILEWCVLS 461
++ + A+ + + DN + W P E K Y++ + S
Sbjct 660 ------GLVHYFGAELAASSLLEAMPFTVGDNQTYRGFWNPPLEPRKAYLIYFQAAS 710
Score = 85.7 bits (210), Expect = 2e-15, Method: Composition-based stats.
Identities = 47/279 (17%), Positives = 89/279 (32%), Gaps = 25/279 (9%)
Query 361 GKILDYEVTLTRWKSHLQNY---TVNATKLTVNLTNDRYLATLTVR----NLVGKSDAAV 413
G I+ E+ + + KL + Y ++ + G+ +
Sbjct 315 GPIVRKEIEYRMARGPWAEVHAVNLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPL 374
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK---YILEWCVLSDKAPCITDW 470
++ C P A + L ++W +V + Y + C
Sbjct 375 ISRTKCAEPTRAPKGLAFAEIQARQLTLQWEPLGYNVTRCHTYAVSLCYRYTLGGSHNQT 434
Query 471 QQEDGTVHR---TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK-GPTVR 526
+E + R Y NL + + + +G + + + P
Sbjct 435 IRECVKMERGASRYTIKNLLPFRNIHVRLILTNPEGRKEGKEVTFQTDEDVPGGIAAESL 494
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS---------SHTEY 577
T ++ L+W++ NG I Y I Y++I ++ AVNV + T +
Sbjct 495 TFTPLEDMIFLKWEE--PQEPNGLITQYEISYQSIESSDPAVNVPGPRRTISKLRNETYH 552
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
S+L T Y+ + A T +G TT A
Sbjct 553 VFSNLHPGTTYLFSVRARTSKGFGQAALTEITTNISAPS 591
Score = 66.4 bits (160), Expect = 1e-09, Method: Composition-based stats.
Identities = 44/239 (18%), Positives = 79/239 (33%), Gaps = 43/239 (18%)
Query 407 GKSDAAVLTIPACDFQ-ATHPVMDLKAFPKDNMLWVEWTTPR----ESVKKYILEWCVLS 461
G + + + P L+A P L ++ T + + +E+ +
Sbjct 271 GAGVSNFAELIVKEPPTPIAPPQLLRAGP--TYLIIQLNTNSIIGDGPIVRKEIEYRM-- 326
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV---TPVYADGPGSPESIKAYLKQAP 518
W + +TY +L Y I+V P + + K A
Sbjct 327 ----ARGPWAEVHAVNLQTYKLWHLDPDTEYEISVLLTRPGDGGTGRPGPPLISRTKCAE 382
Query 519 PSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI----------FYRTIIGNE-- 565
P++ P + ++ + L+W+ L Y + YR +G
Sbjct 383 PTRAPKGLAFAEIQARQLTLQWEPL----------GYNVTRCHTYAVSLCYRYTLGGSHN 432
Query 566 ----TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
V ++ + YT+ +L VR+ EG K+G E TF T + G I A
Sbjct 433 QTIRECVKMERGASRYTIKNLLPFRNIHVRLILTNPEGRKEGKEVTFQTDEDVPGGIAA 491
>sp|Q90344|EPHB2_COTJA Ephrin type-B receptor 2 OS=Coturnix japonica
OX=93934 GN=EPHB2 PE=2 SV=1
Length=987
Score = 111 bits (278), Expect = 1e-23, Method: Composition-based stats.
Identities = 44/214 (21%), Positives = 78/214 (36%), Gaps = 21/214 (10%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADCKAK-RDTP 179
P P+++ VNE + EW GRE + C + P
Sbjct 326 PSAPQSVISSVNE-TSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQFAP 384
Query 180 TSCTVDYSTVY------FVNIEVWVEAENALGKVTSDHINFDPVYKVK-PNPPHNLSVIN 232
+ +Y ++A N + + F V P +S+++
Sbjct 385 RQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMH 444
Query 233 SEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ + L+W+ P + +IL Y +QY K+ S++ S ++ TVQ+LK
Sbjct 445 QVSRTVDSITLSWSQPDQPNGVILDYELQYYEKNL---SELNSTAVKSPTNTVTVQNLKA 501
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
T YVF++R G G + S + T +
Sbjct 502 GTIYVFQVRARTVAGYGRY---SGKMYFQTMTEA 532
Score = 107 bits (266), Expect = 3e-22, Method: Composition-based stats.
Identities = 46/234 (20%), Positives = 82/234 (35%), Gaps = 22/234 (9%)
Query 386 KLTVNLTNDRYLATLTV-RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
+N AT V RN ++DA + +P + + + + L +EWT
Sbjct 289 HCPINSRTTSEGATNCVCRNGYYRADADPVDMPCTTIPSA--PQSVISSVNETSLMLEWT 346
Query 445 TPRESVKKYILEWCVL-----------SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
PR+S + L + ++ + + ++ G +L Y
Sbjct 347 PPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQFAPRQLGLTEPRIYISDLLAHTQYT 406
Query 494 ITVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
+ V SP S+ QA PS + + L W Q D N
Sbjct 407 FEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQ--PDQPN 464
Query 549 GFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
G I +Y + +Y + + V S T+ +L + T+Y+ ++ A T G
Sbjct 465 GVILDYELQYYEKNLSELNSTAVKSPTNTVTVQNLKAGTIYVFQVRARTVAGYG 518
Score = 77.6 bits (189), Expect = 3e-13, Method: Composition-based stats.
Identities = 44/218 (20%), Positives = 71/218 (33%), Gaps = 25/218 (11%)
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRT 263
G +D D P+ P ++ S + L L WT P L YNI ++
Sbjct 309 GYYRADADPVDMPCTTIPSAPQSV---ISSVNETSLMLEWTPPRDSGGREDLVYNIICKS 365
Query 264 KDAS--------TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE-DGKGYWSDWS 314
+ Q P T + DL T+Y F I+ + + +S
Sbjct 366 CGSGRGACTRCGDNVQFAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQF 425
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL---- 370
+ T + PS I ++ ++ L W P + NG ILDYE+
Sbjct 426 ASVNITTNQAAPSA-----VSIMHQVSRTVDSITLSWSQ--PDQPNGVILDYELQYYEKN 478
Query 371 -TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG 407
+ S N + Y+ + R + G
Sbjct 479 LSELNSTAVKSPTNTVTVQNLKAGTIYVFQVRARTVAG 516
>sp|O70468|MYPC3_MOUSE Myosin-binding protein C, cardiac-type
OS=Mus musculus OX=10090 GN=Mybpc3 PE=1 SV=1
Length=1270
Score = 111 bits (278), Expect = 1e-23, Method: Composition-based stats.
Identities = 70/459 (15%), Positives = 132/459 (29%), Gaps = 29/459 (6%)
Query 107 TFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN--FTLKSEW 164
G+ + N+ I P PK +W+ + + L+ +
Sbjct 752 PVGEDQVNLTVKVIDVPDAPAAPKI---SNVGEDSCTVQWEPPAYDGGQPVLGYILERKK 808
Query 165 ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNP 224
+ V E+ V A NA+G + + P
Sbjct 809 KKSYRWMRLNFDLLRELSHEARRMIEGVAYEMRVYAVNAVGMSRPSPASQPFMPIGPPGE 868
Query 225 PHNLSVINSEELSSILKLTWTNPSI-KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P +L+V + + + + L W P + + Y+++Y + S W+ P + R S
Sbjct 869 PTHLAVEDVSD--TTVSLKWRPPERVGAGGLDGYSVEYCQEGCSEWT--PALQGLTERRS 924
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSFWYKIDPSHTQ 342
V+DL +FR+R G G E + RP + P +
Sbjct 925 MLVKDLPTGARLLFRVRAHNVAGPGGPIVTKEPVTVQEILQRPRLQLPRHLRQTIQKKVG 984
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS-HLQNYTVNATKLTVNLTNDRYLATLT 401
+ + ++ P + + + T+ + + Y T+
Sbjct 985 EPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRTHSGTYQVTVR 1044
Query 402 VRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM-LWVEWTTPRESVKKYILEWCVL 460
+ N+ D A L + D P D++ + +EW P++ I + V
Sbjct 1045 IENM---EDKATLILQIVD--KPSPPQDIRIVETWGFNVALEWKPPQDDGNTEIWGYTVQ 1099
Query 461 SDKAPCITDWQQEDGTVHRTY-LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
+W RT+ + L Y V G A K+
Sbjct 1100 KADK-KTMEWFTVLEHYRRTHCVVSELIIGNGYYFRVFSHNMVG---SSDKAAATKEPVF 1155
Query 520 SKGPTVRTKKVGKNEAVLEWDQLP----VDVQNGFIRNY 554
P + + + P I Y
Sbjct 1156 IPRPGITYEPPKYKALDFS--EAPSFTQPLANRSIIAGY 1192
Score = 102 bits (254), Expect = 7e-21, Method: Composition-based stats.
Identities = 45/220 (20%), Positives = 80/220 (36%), Gaps = 10/220 (5%)
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
D + T+TV+N VG+ D LT+ D + +D+ V+W P +
Sbjct 740 EDEGVYTVTVKNPVGE-DQVNLTVKVIDVPDAPAAPKISNVGEDSCT-VQWEPPAYDGGQ 797
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRG--NLAESKCYLITVTPVYADGPGSPESI 510
+L + +L K W + + + R + E Y + V V A G P
Sbjct 798 PVLGY-ILERKKKKSYRWMRLNFDLLRELSHEARRMIEGVAYEMRVYAVNAVGMSRPSPA 856
Query 511 -KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAV 568
+ ++ PP + + + V L+W P V G + Y++ Y + T
Sbjct 857 SQPFMPIGPPGEPTHLAVEDVSDTTVSLKWRP-PERVGAGGLDGYSVEYCQEGCSEWTPA 915
Query 569 NVDSSHT-EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
+ + L + + R+ A+ G GP T
Sbjct 916 LQGLTERRSMLVKDLPTGARLLFRVRAHNVAG-PGGPIVT 954
>sp|P28693|EPHB2_CHICK Ephrin type-B receptor 2 OS=Gallus gallus
OX=9031 GN=EPHB2 PE=1 SV=3
Length=1004
Score = 111 bits (277), Expect = 1e-23, Method: Composition-based stats.
Identities = 44/214 (21%), Positives = 77/214 (36%), Gaps = 21/214 (10%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADCKAK-RDTP 179
P P+ + VNE + EW GRE + C + P
Sbjct 326 PSAPQAVISSVNE-TSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQFAP 384
Query 180 TSCTVDYSTVY------FVNIEVWVEAENALGKVTSDHINFDPVYKVK-PNPPHNLSVIN 232
+ +Y ++A N + + F V P +S+++
Sbjct 385 RQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMH 444
Query 233 SEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ + L+W+ P + +IL Y +QY K+ S++ S ++ TVQ+LK
Sbjct 445 QVSRTVDSITLSWSQPDQPNGVILDYELQYYEKNL---SELNSTAVKSPTNTVTVQNLKA 501
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
T YVF++R G G + S + T +
Sbjct 502 GTIYVFQVRARTVAGYGRY---SGKMYFQTMTEA 532
Score = 108 bits (268), Expect = 2e-22, Method: Composition-based stats.
Identities = 54/288 (19%), Positives = 99/288 (34%), Gaps = 31/288 (11%)
Query 386 KLTVNLTNDRYLATLTV-RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
+N AT V RN ++DA + +P + + + + L +EWT
Sbjct 289 HCPINSRTTSEGATNCVCRNGYYRADADPVDMPCTTIPSA--PQAVISSVNETSLMLEWT 346
Query 445 TPRESVKKYILEWCVL-----------SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
PR+S + L + ++ + + ++ G +L Y
Sbjct 347 PPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQFAPRQLGLTEPRIYISDLLAHTQYT 406
Query 494 ITVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
+ V SP S+ QA PS + + L W Q D N
Sbjct 407 FEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQ--PDQPN 464
Query 549 GFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK--DG-- 603
G I +Y + +Y + + V S T+ +L + T+Y+ ++ A T G G
Sbjct 465 GVILDYELQYYEKNLSELNSTAVKSPTNTVTVQNLKAGTIYVFQVRARTVAGYGRYSGKM 524
Query 604 -----PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDL 646
E + T + + L FL+ ++ ++ C +R
Sbjct 525 YFQTMTEAEYQTSVQEKLPLIIGSSAAGLVFLIAVVVIIIVCNRRRGF 572
Score = 77.6 bits (189), Expect = 4e-13, Method: Composition-based stats.
Identities = 46/226 (20%), Positives = 73/226 (32%), Gaps = 28/226 (12%)
Query 200 AENAL---GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IIL 255
A N + G +D D P+ P + S + L L WT P L
Sbjct 301 ATNCVCRNGYYRADADPVDMPCTTIPSAPQ---AVISSVNETSLMLEWTPPRDSGGREDL 357
Query 256 KYNIQYRTKDAS--------TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE-DG 306
YNI ++ + Q P T + DL T+Y F I+ +
Sbjct 358 VYNIICKSCGSGRGACTRCGDNVQFAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTD 417
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
+ +S + T + PS I ++ ++ L W P + NG ILDY
Sbjct 418 QSPFSPQFASVNITTNQAAPSA-----VSIMHQVSRTVDSITLSWSQ--PDQPNGVILDY 470
Query 367 EVTL-----TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG 407
E+ + S N + Y+ + R + G
Sbjct 471 ELQYYEKNLSELNSTAVKSPTNTVTVQNLKAGTIYVFQVRARTVAG 516
>sp|Q03137|EPHA4_MOUSE Ephrin type-A receptor 4 OS=Mus musculus
OX=10090 GN=Epha4 PE=1 SV=2
Length=986
Score = 111 bits (277), Expect = 1e-23, Method: Composition-based stats.
Identities = 44/219 (20%), Positives = 83/219 (38%), Gaps = 23/219 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWAT----HKFADC------ 172
PP P NL VNE + EW + T + ++ + + K C
Sbjct 328 PPSAPLNLISNVNE-TSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHY 386
Query 173 -KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSV 230
+ T+ + N + A N + K S + P ++++
Sbjct 387 TPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVSKYNPSPDQSVSVTVTTNQAAPSSIAL 446
Query 231 INSEELSSI-LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
+ ++E++ + L W P + +IL+Y ++Y KD ++ + + ++ L
Sbjct 447 VQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKD---QNERSYRIVRTAARNTDIKGL 503
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
P T YVF +R G G +S+ E +T PS+
Sbjct 504 NPLTSYVFHVRARTAAGYGDFSEPLE----VTTNTVPSR 538
Score = 103 bits (257), Expect = 3e-21, Method: Composition-based stats.
Identities = 50/283 (18%), Positives = 92/283 (33%), Gaps = 27/283 (10%)
Query 357 FEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR-YLATLTVRNLVGKSDAAVLT 415
E NG+ ++ + S +A+ + + + G A
Sbjct 267 EEQNGECQACKIGYYKALST------DASCAKCPPHSYSVWEGATSCTCDRGFFRADNDA 320
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL---------SDKAPC 466
+ ++L + + + +EW++P+ + + + + V+ S PC
Sbjct 321 ASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPC 380
Query 467 ITDWQ---QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-----SIKAYLKQAP 518
+ Q++G +L Y + V +P S+ QA
Sbjct 381 GSGVHYTPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVSKYNPSPDQSVSVTVTTNQAA 440
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA-VNVDSSHTEY 577
PS V+ K+V + L W + D NG I Y + Y NE + V ++
Sbjct 441 PSSIALVQAKEVTRYSVALAWLE--PDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNT 498
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
+ L T Y+ + A T G D E T I
Sbjct 499 DIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIG 541
Score = 84.1 bits (206), Expect = 3e-15, Method: Composition-based stats.
Identities = 49/240 (20%), Positives = 79/240 (33%), Gaps = 29/240 (12%)
Query 192 VNIEVWVEAEN---ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
+ VW A + G +D+ P+ P NL S + + L W++P
Sbjct 296 HSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNL---ISNVNETSVNLEWSSPQ 352
Query 249 IKSVI-ILKYNIQYRTKDASTWS---------QIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ YN+ + A S P+ + ++ DL T Y F
Sbjct 353 NTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTRVSITDLLAHTNYTFE 412
Query 299 IRCMKEDGKGYWS-DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
I + K S D S + T + PS + + +V L W L P
Sbjct 413 IWAVNGVSKYNPSPDQSVSVTVTTNQAAPSS-----IALVQAKEVTRYSVALAW--LEPD 465
Query 358 EANGKILDYEVTLTRWKSHLQNY-----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
NG IL+YEV + ++Y T + Y+ + R G D +
Sbjct 466 RPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFS 525
>sp|Q8QFP9|TYRO3_XENLA Tyrosine-protein kinase receptor TYRO3
OS=Xenopus laevis OX=8355 GN=tyro3 PE=1 SV=1
Length=880
Score = 110 bits (275), Expect = 2e-23, Method: Composition-based stats.
Identities = 72/414 (17%), Positives = 134/414 (32%), Gaps = 46/414 (11%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPK-EQYTIINRTASSVTF---T 92
V C L+ + I W + + +Q I ++F
Sbjct 39 TVSQGHEAKLNCSLQ-------GIEEPEIQWLKDGVPVQSADQMYIPVDEDHWISFLSLK 91
Query 93 DIASLNI-QLTCNILTFGQLEQNVYGITIISGLPP--EKPKNLSCIVNEGKKMRCEWDGG 149
++ + + C G+ + ++ G+P +PK+LS N M C G
Sbjct 92 NVERPDAGKYWCEAEHSGRKSVSDAIWIMVEGVPYFTLEPKDLSVTPNSPFNMTCAAVGP 151
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS 209
E L W K++ +V + EA NA G +S
Sbjct 152 PEP-------LVIIWWVGDSPLGKSESSP----SVLQMSGIHERTAFSCEAHNAKGVSSS 200
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW 269
K P PP N+++ S +TW +I IQ ++ +
Sbjct 201 --RTAIVEVKGLPYPPFNVTISKVTG--STATVTWFPGFNSFSLIKSCTIQVQSLHGN-- 254
Query 270 SQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
++ ++ + + +L+P T + R++C E G +++W + T E P
Sbjct 255 REMYSRLISAPPFAVLLDELQPLTNHSVRVQCTNEMGASPFTEW---RTFHTKETVPQLL 311
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV--NATKL 387
P + T+ ++ L W+ + P IL ++V + + V N L
Sbjct 312 PQ-----NVHMTKTETSLLLDWEEVEPDREGYNILGFKVQWEQENATQGELFVQENQANL 366
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
T + + N G + + +A + P M WV
Sbjct 367 TKWNPEKDLTIRICIANAAGCGPWSEFLLAGSKEEAGK-----QRHPHTRMSWV 415
Score = 74.5 bits (181), Expect = 3e-12, Method: Composition-based stats.
Identities = 40/289 (14%), Positives = 84/289 (29%), Gaps = 13/289 (4%)
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
A G + S L + + L ++ ++R + N G S ++ I
Sbjct 148 AVGPPEPLVIIWWVGDSPLGKSESSPSVLQMSGIHERTAFSCEAHNAKGVS-SSRTAIVE 206
Query 419 CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA--PCITDWQQEDGT 476
P + + V W S +++ C + ++ + +
Sbjct 207 VKGLPYPPFNVTISKVTGSTATVTWFPGFNSFS--LIKSCTIQVQSLHGNREMYSRLISA 264
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVGKNEA 535
L L + + V G + + K+ P P +
Sbjct 265 PPFAVLLDELQPLTNHSVRVQCTNEMGASPFTEWRTFHTKETVPQLLPQNVHMTKTETSL 324
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
+L+W+++ D + I + + + + + V + T + D + +A
Sbjct 325 LLDWEEVEPDREGYNILGFKVQWEQENATQGELFVQENQANLTKWNPEKDLTIRICIA-- 382
Query 596 TDEGGKDGPEFTFTTPKFAQGEIEAIV-----VPVCLAFLLTTLLGVLF 639
G EF K G+ VP+ L L + V
Sbjct 383 NAAGCGPWSEFLLAGSKEEAGKQRHPHTRMSWVPMVLGILTALVTVVAM 431
>sp|Q07498|EPHB3_CHICK Ephrin type-B receptor 3 (Fragment) OS=Gallus
gallus OX=9031 GN=EPHB3 PE=2 SV=1
Length=988
Score = 110 bits (274), Expect = 3e-23, Method: Composition-based stats.
Identities = 44/217 (20%), Positives = 72/217 (33%), Gaps = 22/217 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAK-RDT 178
P P+++ VNE + EW GGR+ L K + C
Sbjct 311 VPSAPRSVISNVNE-TSLVLEWSEPQDAGGRDDLLYNVICKKCSVERRLCSRCDDNVEFV 369
Query 179 PTSCTVDYSTVY---------FVNIEVWVEAENALGKVTSDHINFDPVYKV--KPNPPHN 227
P + T ++A N + + +F V + P
Sbjct 370 PRQLGLTGLTERRIYISKVMAHPQYTFEIQAVNGISSKSPYPPHFASVNITTNQAAPSAV 429
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
++ + + L+WT P + IIL Y I+Y K S ++S +
Sbjct 430 PTMHLHSSTGNSMTLSWTPPERPNGIILDYEIKYSEKQGQGDGIANT--VTSQKNSVRLD 487
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
LK Y+ ++R G G +S +E T ED
Sbjct 488 GLKANARYMVQVRARTVAGYGRYSLPTE--FQTTAED 522
Score = 102 bits (254), Expect = 6e-21, Method: Composition-based stats.
Identities = 57/289 (20%), Positives = 91/289 (31%), Gaps = 33/289 (11%)
Query 385 TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
+ N AT+ + G A + + + + L +EW+
Sbjct 274 SPCPPNSRTTAGAATVCI-CRSGFFRADADPADSACTSVPSAPRSVISNVNETSLVLEWS 332
Query 445 TPRESVKKYILEWCVLSDK--------APCITDWQQED------GTVHRTYLRGNLAESK 490
P+++ + L + V+ K + C + + G R +
Sbjct 333 EPQDAGGRDDLLYNVICKKCSVERRLCSRCDDNVEFVPRQLGLTGLTERRIYISKVMAHP 392
Query 491 CYLITVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
Y + V SP S+ QA PS PT+ N L W P +
Sbjct 393 QYTFEIQAVNGISSKSPYPPHFASVNITTNQAAPSAVPTMHLHSSTGNSMTLSW--TPPE 450
Query 546 VQNGFIRNYTIFYRTIIGNETAV--NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK-- 601
NG I +Y I Y G + V S L L ++ YMV++ A T G
Sbjct 451 RPNGIILDYEIKYSEKQGQGDGIANTVTSQKNSVRLDGLKANARYMVQVRARTVAGYGRY 510
Query 602 DGPEFTFTTPKFAQG-----EIEAIVVPVCLAFLL--TTLLGVLFCFNK 643
P TT + E+ IV L ++ + CF K
Sbjct 511 SLPTEFQTTAEDGSTSKTFQELPLIVGSATAGLLFVIVVVIIAIVCFRK 559
Score = 75.7 bits (184), Expect = 1e-12, Method: Composition-based stats.
Identities = 47/241 (20%), Positives = 82/241 (34%), Gaps = 26/241 (11%)
Query 213 NFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK--------SVIILKYNIQYRTK 264
+ DP + P + S + L L W+ P +VI K +++ R
Sbjct 300 DADPADSACTSVPSAPRSVISNVNETSLVLEWSEPQDAGGRDDLLYNVICKKCSVERRLC 359
Query 265 D--ASTWSQIPPED--TASTRSSFTVQDLKPFTEYVFRIRCMKEDG-KGYWSDWSEEASG 319
+P + T T + + +Y F I+ + K + +
Sbjct 360 SRCDDNVEFVPRQLGLTGLTERRIYISKVMAHPQYTFEIQAVNGISSKSPYPPHFASVNI 419
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN 379
T + PS P+ H+ ++ L W PP NG ILDYE+ + +
Sbjct 420 TTNQAAPSAVPTMHL-----HSSTGNSMTLSW--TPPERPNGIILDYEIKYSEKQGQGDG 472
Query 380 Y--TVNATKLTVNLT----NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF 433
TV + K +V L N RY+ + R + G ++ T + +
Sbjct 473 IANTVTSQKNSVRLDGLKANARYMVQVRARTVAGYGRYSLPTEFQTTAEDGSTSKTFQEL 532
Query 434 P 434
P
Sbjct 533 P 533
>sp|Q80YX1|TENA_MOUSE Tenascin OS=Mus musculus OX=10090 GN=Tnc
PE=1 SV=1
Length=2110
Score = 110 bits (275), Expect = 3e-23, Method: Composition-based stats.
Identities = 69/470 (15%), Positives = 136/470 (29%), Gaps = 46/470 (10%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
+NL+ W +F + + + +
Sbjct 1442 ENLTISDTNPYGFTVSWTASENAF--DSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLI 1499
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+ EV V G T + + + + +P NL V S+ +L+WT
Sbjct 1500 TGIGYEVLVSGFTQ-GHQT-KPLRAETITEAEPEV-DNLLV--SDATPDGFRLSWTA--- 1551
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
I + I+ R D S+ S + + L+ TEY + +
Sbjct 1552 DEGIFDSFVIRIR--DTKKQSEPQEISLPSPERTRDITGLREATEYEIELYGISR----- 1604
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
S+ S I S + I + W+ P V
Sbjct 1605 -GRRSQPVSAIATTAMGSPKEIMFSDIT------ENAATVSWRA--PTAQVESFRITYVP 1655
Query 370 LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG---KSDAAVLTIPACDFQATHP 426
+T + T+ + ++V + G + I A D +
Sbjct 1656 MTGGAPSMVTVDGTDTETRLVKLTPGVEYRVSVIAMKGFEESDPVSGTLITALDGPSGLL 1715
Query 427 VMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
+ ++ D+ W +V Y++ + + + + Y +L
Sbjct 1716 IANIT----DSEALAMWQPAIATVDSYVISY-----TGERVPEVTRTVSGNTVEYELHDL 1766
Query 487 AESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDV 546
+ Y++++ S + K P + +V A+L W
Sbjct 1767 EPATEYILSIFAEKGQQKSSTIATKFTTDLDSPRE---FTATEVQSETALLTWRPPRAS- 1822
Query 547 QNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
+ Y + Y ++ G V V T Y+L+ L+ T Y R+ A +
Sbjct 1823 ----VTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYSARIQALS 1868
Score = 108 bits (268), Expect = 2e-22, Method: Composition-based stats.
Identities = 93/577 (16%), Positives = 170/577 (29%), Gaps = 65/577 (11%)
Query 60 VNANYIVWKTNHFTIPKEQ--YTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYG 117
I W I + Y I + T N N+ + E ++
Sbjct 816 DTTALITWFKPLAEIDSIELSYGIKDVPGDRTTIDLTHEDNQYSIGNLRPDTEYEVSLIS 875
Query 118 ITIISGLPP---------EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHK 168
+ P + P+NL + + EW + ++ +K +
Sbjct 876 RRVDMASNPAKETFITGLDAPRNLRRVSQTDNSITLEWRNVKADI--DSYRIKYAPISGG 933
Query 169 FADCKAKRDTPTSCTVDYSTVYF-----VNIEVWVEAENALGKVTSDHINFDPVYKVKPN 223
A+ D P S T + V A G SD + ++ +
Sbjct 934 DH---AEIDVPKSQQATTKTTLTGLRPGTEYGIGVSAVK--GDKESDPATINAATEI--D 986
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P +L V SE L WT P +Y + Y + P+D +S
Sbjct 987 APKDLRV--SETTQDSLTFFWTTPLA---KFDRYRLNYSLPTGQSMEVQLPKDA----TS 1037
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI-TYEDRPSKAPSFWYKIDPSHTQ 342
+ DL+P EY + K K S+ A + E+ PS +
Sbjct 1038 HVLTDLEPGQEYTVLLIAEKGRHK------SKPARVKASTEEVPS------LENLTVTEA 1085
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTV 402
G+ ++L W ++ + +H N + +++
Sbjct 1086 GWDGLRLNWTADDLAYEY-FVIQVQEANNVETAHNFTVPGNLRAADIPGLKVATSYRVSI 1144
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD 462
+ VL+ + A + L + WT P + K + ++ VL
Sbjct 1145 YGVARGYRTPVLSAETSTGTTPNLGEVTVAEVGWDALTLNWTAPEGAYKNFFIQ--VLEA 1202
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
G + L G L + Y IT+ V D +P S++ + P G
Sbjct 1203 DTTQTVQNLTVPGGLRSVDLPG-LKAATRYYITLRGVTQDFGTAPLSVEVLTEDLPQLGG 1261
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLS 580
+ +V + L W + +++ + + E + V S +
Sbjct 1262 --LSVTEVSWDGLTLNWTTDDLAY-----KHFVVQVQEANNVEAAQNLTVPGSLRAVDIP 1314
Query 581 SLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
L +DT Y V + G G + +
Sbjct 1315 GLKADTPYRVSIY-----GVIQGYRTPMLSTDVSTAR 1346
Score = 108 bits (268), Expect = 2e-22, Method: Composition-based stats.
Identities = 72/381 (19%), Positives = 122/381 (32%), Gaps = 46/381 (12%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP +L V +E + L W + + +Y I Y A ++S
Sbjct 625 PPKDLIV--TEVTEETVNLAW----DNEMRVTEYLIMYTPTHADGLEM--QFRVPGDQTS 676
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
T+++L+P EY R+ + E+ S S P+ + +
Sbjct 677 TTIRELEPGVEYFIRVFAILEN------KRSIPVSARVATYLPAP------EGLKFKSIK 724
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWK--SHLQNYTVNATKLTVNLTNDRYLATLT 401
+V++ W L +I+ + + + + T Y +L
Sbjct 725 ETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLH 784
Query 402 VR--NLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
+ N G V T D + V D+ D + W P + L + +
Sbjct 785 IVKNNTRGPGLKKVTTTR-LDAPSHIEVKDVT----DTTALITWFKPLAEIDSIELSYGI 839
Query 460 LS-DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP 518
D ED Y GNL Y +++ D +P
Sbjct 840 KDVPGDRTTIDLTHED----NQYSIGNLRPDTEYEVSLISRRVDMASNPAKETFITGLDA 895
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI-IGNETAVNVDSSH--- 574
P +R N LEW + D I +Y I Y I G+ ++V S
Sbjct 896 PR---NLRRVSQTDNSITLEWRNVKAD-----IDSYRIKYAPISGGDHAEIDVPKSQQAT 947
Query 575 TEYTLSSLTSDTLYMVRMAAY 595
T+ TL+ L T Y + ++A
Sbjct 948 TKTTLTGLRPGTEYGIGVSAV 968
Score = 85.3 bits (209), Expect = 2e-15, Method: Composition-based stats.
Identities = 50/379 (13%), Positives = 116/379 (31%), Gaps = 41/379 (11%)
Query 127 EKPK--NLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
+P+ NL R W + + +F ++ + + +P
Sbjct 1528 AEPEVDNLLVSDATPDGFRLSWT--ADEGIFDSFVIRIRDTKKQSEPQEISLPSPERTRD 1585
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
E+ + + G+ + P ++ S+ + ++W
Sbjct 1586 ITGLREATEYEIELYGISR-GRRSQPVSAIATTAMGSPK-----EIMFSDITENAATVSW 1639
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
P+ + + + I Y S + + T + + L P EY + M
Sbjct 1640 RAPTAQ---VESFRITYVPMTGGAPSMVTVDGTDTETR---LVKLTPGVEYRVSVIAM-- 1691
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
KG+ + S+ SG PS + + ++ +W+ A +
Sbjct 1692 --KGF--EESDPVSGTLITA--LDGPSGLLIANITDSEA----LAMWQP-----AIATVD 1736
Query 365 DYEVTLTRWK--SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
Y ++ T + + + N + ++ L++ G+ ++ +
Sbjct 1737 SYVISYTGERVPEVTRTVSGNTVEYELHDLEPATEYILSIFAEKGQQKSSTIATKFTTDL 1796
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
+ + L + W PR SV Y+L + + T + G +Y
Sbjct 1797 DSPREFTATEVQSETAL-LTWRPPRASVTGYLLVYESVDG-----TVKEVIVGPDTTSYS 1850
Query 483 RGNLAESKCYLITVTPVYA 501
+L+ S Y + +
Sbjct 1851 LADLSPSTHYSARIQALSG 1869
Score = 78.4 bits (191), Expect = 2e-13, Method: Composition-based stats.
Identities = 42/287 (15%), Positives = 99/287 (34%), Gaps = 23/287 (8%)
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN----YTVN 383
P + + TV L W ++ +Y + T + +
Sbjct 624 SPPKDLIVTEVTEE----TVNLAWDNEM------RVTEYLIMYTPTHADGLEMQFRVPGD 673
Query 384 ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEW 443
T T+ + V ++ + ++ + + K+ K+ + VEW
Sbjct 674 QTSTTIRELEPGVEYFIRVFAILENKRSIPVSARVATYLPAPEGLKFKSI-KETSVEVEW 732
Query 444 TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADG 503
+ + + + + ++ + +Y + LA + Y I++ V +
Sbjct 733 DPLDIAFETWEIIFRNMNKEDEGEITKSLRRP--ETSYRQTGLAPGQEYEISLHIVKNNT 790
Query 504 PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
G + PS + K V A++ W + P+ + +Y I + + G
Sbjct 791 RGPGLKKVTTTRLDAPS---HIEVKDVTDTTALITWFK-PLAEIDSIELSYGI--KDVPG 844
Query 564 NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ T +++ +Y++ +L DT Y V + + + + + TF T
Sbjct 845 DRTTIDLTHEDNQYSIGNLRPDTEYEVSLISRRVDMASNPAKETFIT 891
Score = 69.5 bits (168), Expect = 1e-10, Method: Composition-based stats.
Identities = 61/395 (15%), Positives = 121/395 (31%), Gaps = 24/395 (6%)
Query 417 PACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
D P DL + + + W V +Y++ + + + G
Sbjct 616 TGIDCSEVSPPKDLIVTEVTEETVNLAWD-NEMRVTEYLIMYTPTHADGLEMQF--RVPG 672
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
T +R L Y I V + + P S + P ++ K + +
Sbjct 673 DQTSTTIRE-LEPGVEYFIRVFAILENKRSIPVSARVATYLPAPEG---LKFKSIKETSV 728
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN--VDSSHTEYTLSSLTSDTLYMVRMA 593
+EWD L + + I IF +E + + T Y + L Y + +
Sbjct 729 EVEWDPLDIAFETWEI----IFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLH 784
Query 594 AYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFL-----LTTLLGVLFCFNKRDLIK 648
+ G + TT A IE V A + L + + + +D+
Sbjct 785 IVKNNTRGPGLKKVTTTRLDAPSHIEVKDVTDTTALITWFKPLAEIDSIELSYGIKDVPG 844
Query 649 KHIWPNVPDPSKS-HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPED 707
++ I P T + S+ + + + ++A
Sbjct 845 DRTTIDLTHEDNQYSIGNLRPDTEYEVSLISRRVDMASNPAKETFITGLDAPRNLRRVSQ 904
Query 708 LKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGY 767
+ + + + S I + I D +S Q T+ T + Y
Sbjct 905 TDNSITLEWRNVKADIDSYRIKYAPISGGDHAEI---DVPKSQQATTKTTLTGLRPGTEY 961
Query 768 RHQVPSVQVFSRSESTQPLLDSE-ERPEDLQLVDH 801
V +V+ S+ +E + P+DL++ +
Sbjct 962 GIGVSAVKGDKESDPATINAATEIDAPKDLRVSET 996
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 56/491 (11%), Positives = 129/491 (26%), Gaps = 57/491 (12%)
Query 127 EKPKNLSC---IVNEGKKMRCE---WDGGR-----ETHLETNFTLKSEWATHKFADCKAK 175
KP + V + + WDG R + F ++ + A +
Sbjct 1062 SKPARVKASTEEVPSLENLTVTEAGWDGLRLNWTADDLAYEYFVIQVQEANNVETAHNFT 1121
Query 176 RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
+ V + + + + P+ V +E
Sbjct 1122 VPGNLRAADIPGLKVATSYRVSI---YGVARGYRTPVLSAETSTGTT--PNLGEVTVAEV 1176
Query 236 LSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
L L WT P + IQ D + + S + LK T Y
Sbjct 1177 GWDALTLNWTAPE---GAYKNFFIQVLEADTT--QTVQNLTVPGGLRSVDLPGLKAATRY 1231
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ-LVWKTL 354
+R + +D + S + G +V + W L
Sbjct 1232 YITLRGVTQDFG-------------------TAPLSVEVLTEDLPQLGGLSVTEVSWDGL 1272
Query 355 PPF--EANGKILDYEVTLTRWKSHL--QNYTVNAT--KLTVNLTNDRYLATLTVRNLV-G 407
+ + V + + QN TV + + + +++ ++ G
Sbjct 1273 TLNWTTDDLAYKHFVVQVQEANNVEAAQNLTVPGSLRAVDIPGLKADTPYRVSIYGVIQG 1332
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
+ T + + +++ + + WT + +E + D +
Sbjct 1333 YRTPMLSTDVSTAREPEIGNLNVSDVTPKS-FNLSWTATDGIFDMFTIE---IIDSNRLL 1388
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
+ RT L S +++ ++ + + +A P +
Sbjct 1389 QTAEHNISGAERTAHISGLPPSTDFIVYLSGIAP-SIRTKTISTTATTEALPL-LENLTI 1446
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTL 587
+ W + + + + + + + + L L +
Sbjct 1447 SDTNPYGFTVSWTASENAFDSFLVT---VVDSGKLLDPQEFTLSGTQRKLELRGLITGIG 1503
Query 588 YMVRMAAYTDE 598
Y V ++ +T
Sbjct 1504 YEVLVSGFTQG 1514
>sp|P55146|TYRO3_RAT Tyrosine-protein kinase receptor TYRO3 OS=Rattus
norvegicus OX=10116 GN=Tyro3 PE=1 SV=1
Length=880
Score = 109 bits (273), Expect = 4e-23, Method: Composition-based stats.
Identities = 68/435 (16%), Positives = 122/435 (28%), Gaps = 79/435 (18%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPK-EQYTIINRTASSVTF 91
P V C ++ ++ I W + + Q +I + +
Sbjct 39 PVKMTVSQGQPVKLNCSVE-------GMDDPDIHWMKDGAVVQNASQVSISISEQNWIGL 91
Query 92 TDIASLNIQLTCNILTFGQLEQN----------VYGITII------SGLPPEKPKNLSCI 135
+ S + + V G+ +PP P LSC
Sbjct 92 LSLKSAERSDAGLYWCQVKDGEETKISQSVWLTVEGVPFFTVEPKDLAVPPNVPFQLSCE 151
Query 136 V---NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV 192
E + W G K P S +
Sbjct 152 AVGPPEPVTIF-WWRG------------------------PTKVGGPASSPSVLNVTGVT 186
Query 193 N-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS 251
E EA N G TS + P P N++V ++ + W +
Sbjct 187 QRTEFSCEAHNIKGLATSRPAIIRL--QAPPAAPFNITVTTISSSNASV--AWVPGADGL 242
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
++ +Q W + + +++L P T Y R+RC G +
Sbjct 243 ALLHSCTVQV-AHAPGEWEALAVVVPVPP-FTCLLRNLAPATNYSLRVRCANALGPSPYG 300
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA-NGKILDYEVTL 370
DW T P++AP ++ I + L W+ + P + G + Y+++
Sbjct 301 DWVP---FQTKGLAPARAPQNFHAIRTDSG-----LILEWEEVIPEDPGEGPLGPYKLSW 352
Query 371 TRWKSHLQNYTVNATKLTVNLTNDRY----LATLTVRNLVGKSDAAVLTIPACDFQATHP 426
+ V T T NLT+ + + N +G + + + A
Sbjct 353 VQENGTQDELMVEGT--TANLTDWDPQKDLVLRVCASNAIGDGPWSQPLVVSSHDHAG-- 408
Query 427 VMDLKAFPKDNMLWV 441
+ P WV
Sbjct 409 ---RQGPPHSRTSWV 420
Score = 74.1 bits (180), Expect = 4e-12, Method: Composition-based stats.
Identities = 48/257 (19%), Positives = 86/257 (33%), Gaps = 17/257 (7%)
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG--KSDAAVLT 415
EA G + R + + + + L V R + N+ G S A++
Sbjct 151 EAVGPPEPVTIFWWRGPTKVGGPASSPSVLNVTGVTQRTEFSCEAHNIKGLATSRPAIIR 210
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ---Q 472
+ A + + + ++ WV P + V AP +W+
Sbjct 211 LQAPPAAPFNITVTTISSSNASVAWV----PGADGLALLHSCTVQVAHAPG--EWEALAV 264
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVG 531
T L NLA + Y + V A GP + K P++ P
Sbjct 265 VVPVPPFTCLLRNLAPATNYSLRVRCANALGPSPYGDWVPFQTKGLAPARAPQNFHAIRT 324
Query 532 KNEAVLEWDQL-PVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMV 590
+ +LEW+++ P D G + Y + + G + + V+ + T ++
Sbjct 325 DSGLILEWEEVIPEDPGEGPLGPYKLSWVQENGTQDELMVEGTTANLT--DWDPQKDLVL 382
Query 591 RMAAYTDEGGKDGPEFT 607
R+ A G DGP
Sbjct 383 RVCASNAIG--DGPWSQ 397
Score = 53.7 bits (127), Expect = 7e-06, Method: Composition-based stats.
Identities = 60/429 (14%), Positives = 112/429 (26%), Gaps = 73/429 (17%)
Query 410 DAAVLTIPACDFQATHP-VMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCIT 468
+ P + +A + + W V
Sbjct 129 PFFTVEPKDLAVPPNVPFQLSCEAVGPPEPVTIFWWRGPTKVGG-----------PASSP 177
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTK 528
G RT + G + L+ APP+ +
Sbjct 178 SVLNVTGVTQRT------------EFSCEAHNIKGLATSRPAIIRLQ-APPAAPFNITVT 224
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET--AVNVDSSHTEYTLSSLTSDT 586
+ + A + W +P + + T+ G AV V L +L T
Sbjct 225 TISSSNASVAW--VPGADGLALLHSCTVQVAHAPGEWEALAVVVPVPPFTCLLRNLAPAT 282
Query 587 LYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRD 645
Y +R+ G G F T A P + T +L
Sbjct 283 NYSLRVRCANALGPSPYGDWVPFQTKGLAPAR-----APQNFHAIRTDSGLILE------ 331
Query 646 LIKKHIWPNVP-----DPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEAND 700
+ + P P P K Q + + + D+ + +N
Sbjct 332 --WEEVIPEDPGEGPLGPYKLSWVQENGTQDELMVEGTTANLTDWDPQKDLVLRVCASNA 389
Query 701 KKPFPED----LKSLDLFKKEKINTEGHS--SGIGGSSCMSSSRPSISSSDENESSQNTS 754
P + S D ++ S + G + +++ + + T
Sbjct 390 IGDGPWSQPLVVSSHDHAGRQGPPHSRTSWVPVVLGVLTALITAAALALILLRKRRKET- 448
Query 755 STVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQ-LVDHVDGGDG------ 807
++ S P+V F + S + ERPE ++ +D + D
Sbjct 449 ---RFGQAFDSVMARGEPAV-HFRAARSF-----NRERPERIEATLDSLGISDELKEKLE 499
Query 808 --ILPRQQY 814
++P QQ+
Sbjct 500 DVLIPEQQF 508
>sp|Q07494|EPHB1_CHICK Ephrin type-B receptor 1 (Fragment) OS=Gallus
gallus OX=9031 GN=EPHB1 PE=2 SV=2
Length=984
Score = 109 bits (273), Expect = 4e-23, Method: Composition-based stats.
Identities = 37/217 (17%), Positives = 71/217 (33%), Gaps = 31/217 (14%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH-----LETNFTLKSEWATHKFADCKAK-RDT 178
P P+N+ IVNE + EW+ RET K + C
Sbjct 303 VPSGPRNVISIVNE-TSIILEWNPPRETGGRDDVTYNIVCKKCRADRRACSRCDDNVEFV 361
Query 179 PTSCTVDYSTVY------FVNIEVWVEAENALGKVTS-DHINFDPVYKVKPNPPHNLSVI 231
P + + V+ ++A N + + + P + ++
Sbjct 362 PRQLGLTETRVFISSLWAHTPYTFEIQAVNGVSNKSPFPPQHVSVNITTNQAAPSTVPIM 421
Query 232 NSEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDAS----------------TWSQIPP 274
+ + + L+W P + IIL Y ++Y K + ++
Sbjct 422 HQVSATMRSITLSWPQPEQPNGIILDYELRYYEKLSRICTPDVSGTVGSRPAADHNEYNS 481
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
S ++ ++ L+P YV ++R G G +S
Sbjct 482 SVARSQTNTARLEGLRPGMVYVVQVRARTVAGYGKYS 518
Score = 103 bits (257), Expect = 3e-21, Method: Composition-based stats.
Identities = 57/363 (16%), Positives = 106/363 (29%), Gaps = 54/363 (15%)
Query 386 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT 445
+ N + + L G A + A ++ + + + +EW
Sbjct 267 RCPPNSRSSAEASPLCA-CRNGYFRADLDPPTAACTSVPSGPRNVISIVNETSIILEWNP 325
Query 446 PRESVKKYILEW-----------CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
PRE+ + + + S + ++ G +L Y
Sbjct 326 PRETGGRDDVTYNIVCKKCRADRRACSRCDDNVEFVPRQLGLTETRVFISSLWAHTPYTF 385
Query 495 TVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
+ V SP S+ QA PS P + L W Q + NG
Sbjct 386 EIQAVNGVSNKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQ--PEQPNG 443
Query 550 FIRNYTIFYRTIIGNETAVNVDSS--------------------HTEYTLSSLTSDTLYM 589
I +Y + Y + +V + L L +Y+
Sbjct 444 IILDYELRYYEKLSRICTPDVSGTVGSRPAADHNEYNSSVARSQTNTARLEGLRPGMVYV 503
Query 590 VRMAAYTDEG-GKDGPEFTFTTPKFAQGE--------IEAIVVPVCLAFLLTTLLGVLFC 640
V++ A T G GK + F T + + A + F+++ + + C
Sbjct 504 VQVRARTVAGYGKYSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFIVSLVAISIVC 563
Query 641 FNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSD----GNFTDVSVVEI 696
KR K+ ++ + + SP + + + DVS V+I
Sbjct 564 SRKRAYSKEVVYSD--KLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKI 621
Query 697 EAN 699
E
Sbjct 622 EEV 624
Score = 70.3 bits (170), Expect = 6e-11, Method: Composition-based stats.
Identities = 40/256 (16%), Positives = 72/256 (28%), Gaps = 51/256 (20%)
Query 201 ENALGKVTSDHINF--DPVYKVKPNPPH--------NLSVINSEELSSILKLTWTNPSIK 250
N+ + + + ++ +PP + S + + L W P
Sbjct 270 PNSRSSAEASPLCACRNGYFRADLDPPTAACTSVPSGPRNVISIVNETSIILEWNPPRET 329
Query 251 SV-IILKYNIQYRTKDASTWS--------QIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+ YNI + A + + P T + + L T Y F I+
Sbjct 330 GGRDDVTYNIVCKKCRADRRACSRCDDNVEFVPRQLGLTETRVFISSLWAHTPYTFEIQA 389
Query 302 MKEDGKGYWSDWSE-EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
+ + T + PS P I + R++ L W P + N
Sbjct 390 VNGVSNKSPFPPQHVSVNITTNQAAPSTVP-----IMHQVSATMRSITLSW--PQPEQPN 442
Query 361 GKILDYEVTLT------------------------RWKSHLQNYTVNATKLTVNLTNDRY 396
G ILDYE+ + S + N +L Y
Sbjct 443 GIILDYELRYYEKLSRICTPDVSGTVGSRPAADHNEYNSSVARSQTNTARLEGLRPGMVY 502
Query 397 LATLTVRNLVGKSDAA 412
+ + R + G +
Sbjct 503 VVQVRARTVAGYGKYS 518
>sp|P54764|EPHA4_HUMAN Ephrin type-A receptor 4 OS=Homo sapiens
OX=9606 GN=EPHA4 PE=1 SV=1
Length=986
Score = 109 bits (272), Expect = 5e-23, Method: Composition-based stats.
Identities = 43/219 (20%), Positives = 83/219 (38%), Gaps = 23/219 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWAT----HKFADC------ 172
PP P NL VNE + EW + T + ++ + + K C
Sbjct 328 PPSAPLNLISNVNE-TSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHY 386
Query 173 -KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK-VTSDHINFDPVYKVKPNPPHNLSV 230
+ T+ + N + A N + K + + P ++++
Sbjct 387 TPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAPSSIAL 446
Query 231 INSEELSSI-LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
+ ++E++ + L W P + +IL+Y ++Y KD ++ + + ++ L
Sbjct 447 VQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKD---QNERSYRIVRTAARNTDIKGL 503
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
P T YVF +R G G +S+ E +T PS+
Sbjct 504 NPLTSYVFHVRARTAAGYGDFSEPLE----VTTNTVPSR 538
Score = 101 bits (250), Expect = 2e-20, Method: Composition-based stats.
Identities = 52/292 (18%), Positives = 89/292 (30%), Gaps = 40/292 (14%)
Query 352 KTLPPFEANGKILDYEV-----TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLV 406
+ KI Y+ T + H + AT T + N
Sbjct 267 EERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRG------FFRADNDA 320
Query 407 GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL------ 460
++L + + + +EW++P+ + + + + V+
Sbjct 321 ASMPCTR---------PPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGA 371
Query 461 ---SDKAPCITDWQ---QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-----S 509
S PC + Q++G +L Y + V +P S
Sbjct 372 GDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVS 431
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA-V 568
+ QA PS V+ K+V + L W + D NG I Y + Y NE +
Sbjct 432 VTVTTNQAAPSSIALVQAKEVTRYSVALAWLE--PDRPNGVILEYEVKYYEKDQNERSYR 489
Query 569 NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
V ++ + L T Y+ + A T G D E T I
Sbjct 490 IVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIG 541
Score = 80.7 bits (197), Expect = 4e-14, Method: Composition-based stats.
Identities = 48/240 (20%), Positives = 78/240 (33%), Gaps = 29/240 (12%)
Query 192 VNIEVWVEAEN---ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
+ VW A + G +D+ P+ P NL S + + L W++P
Sbjct 296 HSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNL---ISNVNETSVNLEWSSPQ 352
Query 249 IKSVI-ILKYNIQYRTKDASTWS---------QIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ YN+ + A S P+ + ++ DL T Y F
Sbjct 353 NTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFE 412
Query 299 IRCMKEDGKGYW-SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
I + K D S + T + PS + + +V L W L P
Sbjct 413 IWAVNGVSKYNPNPDQSVSVTVTTNQAAPSS-----IALVQAKEVTRYSVALAW--LEPD 465
Query 358 EANGKILDYEVTLTRWKSHLQNY-----TVNATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
NG IL+YEV + ++Y T + Y+ + R G D +
Sbjct 466 RPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFS 525
>sp|P54763|EPHB2_MOUSE Ephrin type-B receptor 2 OS=Mus musculus
OX=10090 GN=Ephb2 PE=1 SV=3
Length=986
Score = 109 bits (272), Expect = 5e-23, Method: Composition-based stats.
Identities = 43/214 (20%), Positives = 75/214 (35%), Gaps = 21/214 (10%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADCKAK-RDTP 179
P P+ + VNE + EW GRE + C + P
Sbjct 325 PSAPQAVISSVNE-TSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYAP 383
Query 180 TSCTVDYSTVY------FVNIEVWVEAENALGKVTSDHINFDPVYKVK-PNPPHNLSVIN 232
+ +Y ++A N + + F V P +S+++
Sbjct 384 RQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMH 443
Query 233 SEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ + L+W+ P + +IL Y +QY K+ S ++ S ++ TVQ LK
Sbjct 444 QVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA---IKSPTNTVTVQGLKA 500
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
YVF++R G G + S + T +
Sbjct 501 GAIYVFQVRARTVAGYGRY---SGKMYFQTMTEA 531
Score = 106 bits (264), Expect = 4e-22, Method: Composition-based stats.
Identities = 53/286 (19%), Positives = 95/286 (33%), Gaps = 31/286 (11%)
Query 385 TKLTVNLTNDRYLATLTV-RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEW 443
T +N AT V RN ++D L +P + + + + L +EW
Sbjct 287 THCPINSRTTSEGATNCVCRNGYYRADLDPLDMPCTTIPSA--PQAVISSVNETSLMLEW 344
Query 444 TTPRESVKKYILEWCVL-----------SDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
T PR+S + L + ++ + + ++ G +L Y
Sbjct 345 TPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQY 404
Query 493 LITVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
+ V SP S+ QA PS + + L W Q D
Sbjct 405 TFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQ--PDQP 462
Query 548 NGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK--DG- 603
NG I +Y + +Y + A + S T+ L + +Y+ ++ A T G G
Sbjct 463 NGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGK 522
Query 604 ------PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNK 643
E + T + + L FL+ ++ + C +
Sbjct 523 MYFQTMTEAEYQTSIKEKLPLIVGSSAAGLVFLIAVVVIAIVCNRR 568
Score = 76.0 bits (185), Expect = 1e-12, Method: Composition-based stats.
Identities = 45/226 (20%), Positives = 74/226 (33%), Gaps = 28/226 (12%)
Query 200 AENAL---GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IIL 255
A N + G +D D P+ P + S + L L WT P L
Sbjct 300 ATNCVCRNGYYRADLDPLDMPCTTIPSAPQ---AVISSVNETSLMLEWTPPRDSGGREDL 356
Query 256 KYNIQYRTKDA--------STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE-DG 306
YNI ++ + Q P T + DL T+Y F I+ +
Sbjct 357 VYNIICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTD 416
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
+ +S + T + PS I ++ ++ L W P + NG ILDY
Sbjct 417 QSPFSPQFASVNITTNQAAPSA-----VSIMHQVSRTVDSITLSWSQ--PDQPNGVILDY 469
Query 367 EVTL-----TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG 407
E+ + + + N + Y+ + R + G
Sbjct 470 ELQYYEKELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAG 515
>sp|P29323|EPHB2_HUMAN Ephrin type-B receptor 2 OS=Homo sapiens
OX=9606 GN=EPHB2 PE=1 SV=5
Length=1055
Score = 109 bits (272), Expect = 5e-23, Method: Composition-based stats.
Identities = 43/214 (20%), Positives = 75/214 (35%), Gaps = 21/214 (10%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADCKAK-RDTP 179
P P+ + VNE + EW GRE + C + P
Sbjct 325 PSAPQAVISSVNE-TSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYAP 383
Query 180 TSCTVDYSTVY------FVNIEVWVEAENALGKVTSDHINFDPVYKVK-PNPPHNLSVIN 232
+ +Y ++A N + + F V P +S+++
Sbjct 384 RQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMH 443
Query 233 SEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ + L+W+ P + +IL Y +QY K+ S ++ S ++ TVQ LK
Sbjct 444 QVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATA---IKSPTNTVTVQGLKA 500
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
YVF++R G G + S + T +
Sbjct 501 GAIYVFQVRARTVAGYGRY---SGKMYFQTMTEA 531
Score = 106 bits (265), Expect = 3e-22, Method: Composition-based stats.
Identities = 53/286 (19%), Positives = 95/286 (33%), Gaps = 31/286 (11%)
Query 385 TKLTVNLTNDRYLATLTV-RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEW 443
T +N AT V RN ++D L +P + + + + L +EW
Sbjct 287 THCPINSRTTSEGATNCVCRNGYYRADLDPLDMPCTTIPSA--PQAVISSVNETSLMLEW 344
Query 444 TTPRESVKKYILEWCVL-----------SDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
T PR+S + L + ++ + + ++ G +L Y
Sbjct 345 TPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQY 404
Query 493 LITVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQ 547
+ V SP S+ QA PS + + L W Q D
Sbjct 405 TFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQ--PDQP 462
Query 548 NGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK--DG- 603
NG I +Y + +Y + A + S T+ L + +Y+ ++ A T G G
Sbjct 463 NGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGK 522
Query 604 ------PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNK 643
E + T + + L FL+ ++ + C +
Sbjct 523 MYFQTMTEAEYQTSIQEKLPLIIGSSAAGLVFLIAVVVIAIVCNRR 568
Score = 76.0 bits (185), Expect = 1e-12, Method: Composition-based stats.
Identities = 45/226 (20%), Positives = 74/226 (33%), Gaps = 28/226 (12%)
Query 200 AENAL---GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IIL 255
A N + G +D D P+ P + S + L L WT P L
Sbjct 300 ATNCVCRNGYYRADLDPLDMPCTTIPSAPQ---AVISSVNETSLMLEWTPPRDSGGREDL 356
Query 256 KYNIQYRTKDA--------STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE-DG 306
YNI ++ + Q P T + DL T+Y F I+ +
Sbjct 357 VYNIICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTD 416
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
+ +S + T + PS I ++ ++ L W P + NG ILDY
Sbjct 417 QSPFSPQFASVNITTNQAAPSA-----VSIMHQVSRTVDSITLSWSQ--PDQPNGVILDY 469
Query 367 EVTL-----TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG 407
E+ + + + N + Y+ + R + G
Sbjct 470 ELQYYEKELSEYNATAIKSPTNTVTVQGLKAGAIYVFQVRARTVAG 515
>sp|O13146|EPHA3_DANRE Ephrin type-A receptor 3 OS=Danio rerio
OX=7955 GN=epha3 PE=1 SV=1
Length=981
Score = 108 bits (270), Expect = 9e-23, Method: Composition-based stats.
Identities = 42/202 (21%), Positives = 73/202 (36%), Gaps = 23/202 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHL--ETNFTLKSEWAT------HKFADC-KAK 175
PP P N +VNE + EW R++ + ++++ + + C
Sbjct 328 PPSAPGNPISMVNE-TAVTLEWSPPRDSGGRGDVSYSVHCRKCSGETGASERCVPCGSGA 386
Query 176 RDTPTSCTVDYSTVY------FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS 229
P + + V N VEA N + ++ V +S
Sbjct 387 HFNPRQFGLTHPRVLVTELQPHTNYTFSVEALNGVSDLSPSPRQLVSVNVTTS---QTVS 443
Query 230 VINSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
VI E + + L W P +++Y + Y K+ + + +S TV
Sbjct 444 VILKERKGTDSVTLAWQGPEPVDGTVVEYEVTYYEKNQQDQN---YTVLKTKSNSMTVDG 500
Query 289 LKPFTEYVFRIRCMKEDGKGYW 310
LKP T Y+FR+R + G G +
Sbjct 501 LKPGTTYIFRVRARTDGGYGNY 522
Score = 99 bits (247), Expect = 5e-20, Method: Composition-based stats.
Identities = 53/296 (18%), Positives = 90/296 (30%), Gaps = 43/296 (15%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ----------- 471
+ + + + +EW+ PR+S + + + V K T
Sbjct 328 PPSAPGNPISMVNETAVTLEWSPPRDSGGRGDVSYSVHCRKCSGETGASERCVPCGSGAH 387
Query 472 ---QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-----SIKAYLKQAPPSKGP 523
++ G H L L Y +V + SP S+ Q
Sbjct 388 FNPRQFGLTHPRVLVTELQPHTNYTFSVEALNGVSDLSPSPRQLVSVNVTTSQTV----S 443
Query 524 TVRTKKVGKNEAVLEWD-QLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSS 581
+ ++ G + L W PVD G + Y + +Y ++ + + T+
Sbjct 444 VILKERKGTDSVTLAWQGPEPVD---GTVVEYEVTYYEKNQQDQNYTVLKTKSNSMTVDG 500
Query 582 LTSDTLYMVRMAAYTDEGGKD-GPEFTFTTPK------FAQGEIEAIVVPVC-LAFLLTT 633
L T Y+ R+ A TD G + E T + + + V A LL
Sbjct 501 LKPGTTYIFRVRARTDGGYGNYKGEIELETSHEDMLAVGDPNQQTILAISVAGGAVLLVL 560
Query 634 LLGVLFCFNKRD-LIKKHIWPNVPDPSKSHIA-QWSPHTPPRHNFNSKDQMYSDGN 687
L+ +R IK DP + + Q P Y D N
Sbjct 561 LVACFIVSGRRCGYIKAKQ-----DPEEEKMQFQHGRVKLPETRTYIHPHTYEDPN 611
Score = 76.0 bits (185), Expect = 1e-12, Method: Composition-based stats.
Identities = 42/210 (20%), Positives = 68/210 (32%), Gaps = 27/210 (13%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII-LKYNIQYRTKDASTWS--- 270
DP PP S + + L W+ P + Y++ R T +
Sbjct 319 DPRSMACTRPPSAPGNPISMVNETAVTLEWSPPRDSGGRGDVSYSVHCRKCSGETGASER 378
Query 271 --------QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
P T V +L+P T Y F + + S + +T
Sbjct 379 CVPCGSGAHFNPRQFGLTHPRVLVTELQPHTNYTFSVEALNGVSDLSPSPRQLVSVNVTT 438
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
S + +G +V L W+ P + G +++YEVT QNYTV
Sbjct 439 --------SQTVSVILKERKGTDSVTLAWQGPEPVD--GTVVEYEVTYYEKNQQDQNYTV 488
Query 383 ---NATKLTVNLTN--DRYLATLTVRNLVG 407
+ +TV+ Y+ + R G
Sbjct 489 LKTKSNSMTVDGLKPGTTYIFRVRARTDGG 518
>sp|Q91735|EPHB3_XENLA Ephrin type-B receptor 3 OS=Xenopus laevis
OX=8355 GN=ephb3 PE=2 SV=1
Length=974
Score = 108 bits (269), Expect = 1e-22, Method: Composition-based stats.
Identities = 43/203 (21%), Positives = 69/203 (34%), Gaps = 17/203 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWAT-HKFADC----KA 174
P P+ + VNE + EW GGR+ L K + D
Sbjct 318 VPSAPRQVISNVNE-TSVVLEWAEPGHLGGRDDVLYNVICKKCLERLCSRCDDNVQFWPR 376
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENAL-GKVTSDHINFDPVYKVKPNPPHNL-SVIN 232
+ ++A N + GK F P ++ V +
Sbjct 377 QLGVTQRLVSVSHLQAHTKYSFEIQAVNGVSGKSPHIPNYFTVNITTNQAAPSSVPMVQS 436
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
L++ L L+W P + IIL Y I+Y K S R++ ++ + P
Sbjct 437 HGSLANSLTLSWAPPESPNGIILDYEIKYYAKGHIG----AGNTVTSQRTTVRMEGMTPD 492
Query 293 TEYVFRIRCMKEDGKGYWSDWSE 315
T YV ++R G G +S+ E
Sbjct 493 TVYVVQVRARTVAGYGAYSEPRE 515
Score = 106 bits (263), Expect = 5e-22, Method: Composition-based stats.
Identities = 48/219 (22%), Positives = 75/219 (34%), Gaps = 23/219 (11%)
Query 407 GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL------ 460
G+S AC + P + + + +EW P + + + V+
Sbjct 308 GESAET-----ACTSVPSAPRQVISNV-NETSVVLEWAEPGHLGGRDDVLYNVICKKCLE 361
Query 461 ---SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-----SIKA 512
S + W ++ G R +L Y + V SP ++
Sbjct 362 RLCSRCDDNVQFWPRQLGVTQRLVSVSHLQAHTKYSFEIQAVNGVSGKSPHIPNYFTVNI 421
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS 572
QA PS P V++ N L W P + NG I +Y I Y V S
Sbjct 422 TTNQAAPSSVPMVQSHGSLANSLTLSW--APPESPNGIILDYEIKYYAKGHIGAGNTVTS 479
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE-FTFTT 610
T + +T DT+Y+V++ A T G E F T
Sbjct 480 QRTTVRMEGMTPDTVYVVQVRARTVAGYGAYSEPREFQT 518
Score = 72.6 bits (176), Expect = 1e-11, Method: Composition-based stats.
Identities = 42/210 (20%), Positives = 69/210 (33%), Gaps = 19/210 (9%)
Query 225 PHNLSVINSEELSSILKLTW-TNPSIKSVIILKYNIQYRTKDASTWS------QIPPEDT 277
P + S + + L W + + YN+ + S Q P
Sbjct 319 PSAPRQVISNVNETSVVLEWAEPGHLGGRDDVLYNVICKKCLERLCSRCDDNVQFWPRQL 378
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKE-DGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
T+ +V L+ T+Y F I+ + GK + T + PS P +
Sbjct 379 GVTQRLVSVSHLQAHTKYSFEIQAVNGVSGKSPHIPNYFTVNITTNQAAPSSVP-----M 433
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN--- 393
SH ++ L W PP NG ILDYE+ TV + + TV +
Sbjct 434 VQSHGSLANSLTLSW--APPESPNGIILDYEIKYYAKGHIGAGNTVTSQRTTVRMEGMTP 491
Query 394 -DRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
Y+ + R + G + +
Sbjct 492 DTVYVVQVRARTVAGYGAYSEPREFQTIAE 521
Score = 54.5 bits (129), Expect = 4e-06, Method: Composition-based stats.
Identities = 25/152 (16%), Positives = 45/152 (30%), Gaps = 10/152 (7%)
Query 367 EVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLV-GKSDAA----VLTIPACDF 421
V + + V+ + L + +Y + N V GKS + I
Sbjct 370 NVQFWPRQLGVTQRLVSVSHLQAH---TKYSFEIQAVNGVSGKSPHIPNYFTVNITTNQA 426
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
+ M N L + W P ES IL++ + I
Sbjct 427 APSSVPMVQSHGSLANSLTLSWAPP-ESPNGIILDYEIKYYAKGHIGAGNTVTSQRTTVR 485
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
+ G + Y++ V G G+ + +
Sbjct 486 MEG-MTPDTVYVVQVRARTVAGYGAYSEPREF 516
>sp|P24821|TENA_HUMAN Tenascin OS=Homo sapiens OX=9606 GN=TNC
PE=1 SV=3
Length=2201
Score = 108 bits (270), Expect = 1e-22, Method: Composition-based stats.
Identities = 70/482 (15%), Positives = 143/482 (30%), Gaps = 42/482 (9%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
+NL+ W +F + + + +
Sbjct 1533 ENLTISDINPYGFTVSWMASENAF--DSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLI 1590
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+ EV V G T + + V + +P NL V S+ +L+WT
Sbjct 1591 TGIGYEVMVSGFTQ-GHQT-KPLRAEIVTEAEPEV-DNLLV--SDATPDGFRLSWTA--- 1642
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ + ++ R D S+ + + + L+ TEY + +
Sbjct 1643 DEGVFDNFVLKIR--DTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGI------- 1693
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
S+ T + A ++ S + + W+ + +I +T
Sbjct 1694 ----SKGRRSQTVSAIATTAMGSPKEVIFSD-ITENSATVSWRAPTAQVESFRITYVPIT 1748
Query 370 LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMD 429
+ T T+L + YL ++ +S+ + P
Sbjct 1749 GGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTT---ALDGPSGL 1805
Query 430 LKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
+ A D+ W +V Y++ + + + + Y +L +
Sbjct 1806 VTANITDSEALARWQPAIATVDSYVISY-----TGEKVPEITRTVSGNTVEYALTDLEPA 1860
Query 490 KCYLITVTPVYADGPGSPESIKA-YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
Y + + GP +I A + + +V A+L W
Sbjct 1861 TEYTLRIFA--EKGPQKSSTITAKFTTDL--DSPRDLTATEVQSETALLTWRPPRAS--- 1913
Query 549 GFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
+ Y + Y ++ G V V T Y+L+ L+ T Y ++ A + + F
Sbjct 1914 --VTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIF 1971
Query 609 TT 610
TT
Sbjct 1972 TT 1973
Score = 107 bits (267), Expect = 3e-22, Method: Composition-based stats.
Identities = 82/500 (16%), Positives = 142/500 (28%), Gaps = 52/500 (10%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP +L +E + L W + + +Y + Y ++S
Sbjct 625 PPKDLV--VTEVTEETVNLAW----DNEMRVTEYLVVYTPTHEGGLEM--QFRVPGDQTS 676
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
+Q+L+P EY R+ + E+ K S S P+ + +
Sbjct 677 TIIQELEPGVEYFIRVFAILENKK------SIPVSARVATYLPAP------EGLKFKSIK 724
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWK--SHLQNYTVNATKLTVNLTNDRYLATL- 400
+V++ W L +I+ + + + + T Y +L
Sbjct 725 ETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLH 784
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
V+N +T D + V D+ D + W P + L + +
Sbjct 785 IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVT----DTTALITWFKPLAEIDGIELTYGIK 840
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS 520
T ED + GNL Y +++ D +P P
Sbjct 841 DVPGDRTTIDLTEDENQYS---IGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPR 897
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI-IGNETAVNVDSSH---TE 576
+R N LEW I +Y I Y I G+ V+V S T+
Sbjct 898 ---NLRRVSQTDNSITLEW-----RNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTK 949
Query 577 YTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLL 635
TL+ L T Y + ++A ++ T + + L L T L
Sbjct 950 TTLTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPL 1009
Query 636 GVLFCFNKRDLIKKHIWPNVPDPSKSHI--------AQWSPHTPPRHNFNSKDQMYSDGN 687
+ + W V P + Q K +
Sbjct 1010 AKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKA 1069
Query 688 FTDVSVVEIEANDKKPFPED 707
T+ E+E D
Sbjct 1070 STE-QAPELENLTVTEVGWD 1088
Score = 106 bits (263), Expect = 8e-22, Method: Composition-based stats.
Identities = 78/470 (17%), Positives = 148/470 (31%), Gaps = 41/470 (9%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
+ P+NL + + EW G+ K T+ T
Sbjct 894 DAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLT 953
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ V A S+ + + + P +L V SE + L L W
Sbjct 954 GLRPGTEYGIGVSAVKE--DKESNPATINAA--TELDTPKDLQV--SETAETSLTLLWKT 1007
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P + K++ +YR + Q +S+ ++ L+P EY + K
Sbjct 1008 P------LAKFD-RYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRH 1060
Query 307 KGYWSDWSEEASGI-TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK-IL 364
K S+ A + E P + ++L W +A I+
Sbjct 1061 K------SKPARVKASTEQAPE--LENLTVTEVGWDG----LRLNWTAAD--QAYEHFII 1106
Query 365 DYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
+ + + + + T+++ ++ VL+ A +
Sbjct 1107 QVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETP 1166
Query 425 HPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
+ + A + L + WT P + + + ++ V G + T L G
Sbjct 1167 NLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQ--VQEADTVEAAQNLTVPGGLRSTDLPG 1224
Query 485 NLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
L + Y IT+ V D +P S++ ++ P G + +V + L W
Sbjct 1225 -LKAATHYTITIRGVTQDFSTTPLSVEVLTEE-VPDMG-NLTVTEVSWDALRLNW----- 1276
Query 545 DVQNGFIRNYTIFYRTIIGNETA--VNVDSSHTEYTLSSLTSDTLYMVRM 592
+G +TI + E A + V S + L + T Y V +
Sbjct 1277 TTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTL 1326
Score = 104 bits (260), Expect = 2e-21, Method: Composition-based stats.
Identities = 77/480 (16%), Positives = 145/480 (30%), Gaps = 54/480 (11%)
Query 127 EKPKNLSCIVNEGKKMRCEW-DGGRE-THLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
+ P + W E +E + +K D +
Sbjct 804 DAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY--SIG 861
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ EV + + G ++S+ + + P NL + + + L W
Sbjct 862 NLKPD--TEYEVSLISRR--GDMSSNPAK--ETFTTGLDAPRNLR--RVSQTDNSITLEW 913
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
N I Y I+Y +++ + + T+ L+P TEY + +KE
Sbjct 914 RNGKA---AIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKE 970
Query 305 DGKGYWSDWSEEASG--ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
D + S A+ T D P ++ L+WKT
Sbjct 971 DKE------SNPATINAATELDTPKDL--------QVSETAETSLTLLWKTPLAKFDR-Y 1015
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
L+Y + +W N T + + + G+ + + A Q
Sbjct 1016 RLNYSLPTGQWVGV--QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQ 1073
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
A + L + WT ++ + +I++ V G++ +
Sbjct 1074 APELENLTVTEVGWDGLRLNWTAADQAYEHFIIQ--VQEANKVEAARNLTVPGSLRAVDI 1131
Query 483 RGNLAESKCYLITVTPVYADGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
G L + Y +++ V G +P S +A + P V +VG + L W
Sbjct 1132 PG-LKAATPYTVSIYGVI-QGYRTPVLSAEASTGETPNLG--EVVVAEVGWDALKLNW-- 1185
Query 542 LPVDVQNGFIRNYTIFYRTIIGNETA-----VNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
G Y F+ + +T + V L L + T Y + + T
Sbjct 1186 ---TAPEGA---YEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVT 1239
Score = 69.9 bits (169), Expect = 1e-10, Method: Composition-based stats.
Identities = 66/413 (16%), Positives = 128/413 (31%), Gaps = 30/413 (7%)
Query 417 PACDFQATHPVMDLKAFPKDNML-WVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
D P DL + W V +Y++ + + + + G
Sbjct 616 SGEDCSEVSPPKDLVVTEVTEETVNLAWD-NEMRVTEYLVVYTPTHEGGLEMQF--RVPG 672
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
T ++ L Y I V + + P S + P ++ K + +
Sbjct 673 DQTSTIIQE-LEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEG---LKFKSIKETSV 728
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN--VDSSHTEYTLSSLTSDTLYMVRMA 593
+EWD L + + I IF +E + + T Y + L Y + +
Sbjct 729 EVEWDPLDIAFETWEI----IFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLH 784
Query 594 AYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFL-----LTTLLGVLFCFNKRDLIK 648
+ G + TT A +IE V A + L + G+ + +D+
Sbjct 785 IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPG 844
Query 649 KHIWPNVPDPSKS-HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPED 707
++ + I P T + S+ S + ++A P +
Sbjct 845 DRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDA------PRN 898
Query 708 LKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDE---NESSQNTSSTVQYSTVVH 764
L+ + + S + + S E +S Q T+ T
Sbjct 899 LRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPG 958
Query 765 SGYRHQVPSVQVFSRSESTQPLLDSE-ERPEDLQLVDHVDGGDGILPRQQYFK 816
+ Y V +V+ S +E + P+DLQ+ + + +L + K
Sbjct 959 TEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAK 1011
>sp|Q98949|TYRO3_CHICK Tyrosine-protein kinase receptor TYRO3
OS=Gallus gallus OX=9031 GN=TYRO3 PE=1 SV=1
Length=873
Score = 107 bits (267), Expect = 2e-22, Method: Composition-based stats.
Identities = 71/390 (18%), Positives = 124/390 (32%), Gaps = 41/390 (11%)
Query 32 SPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPK-EQYTIINRTASSVT 90
SP V C L+ + ++W + + +Q I +
Sbjct 36 SPIKLKVSQGQPVKLNCSLE-------GMEDPEMLWIKDGAVVQSVDQVYIPVDEDHWIG 88
Query 91 FTDIASL----NIQLTCNILTFGQLEQNVYGITIISGLPP--EKPKNLSCIVNEGKKMRC 144
F + S+ + + C + G+ E++ I+ G+P +P+++S N M C
Sbjct 89 FLSLKSVERTDSGKYWCQVENGGKKEESQQVWLIVEGVPYFTVEPEDVSVSPNAPFHMAC 148
Query 145 EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
G E + S + T+ EA N
Sbjct 149 AAVGPPEPVTIVWWMGDSRVGLPDISPSILNVSGINQSTM-----------FSCEAHNVK 197
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK 264
G +S K P PP N++V ++ + W + +Q
Sbjct 198 GLSSS--RTATVQIKAMPLPPLNVTVSQVTSSNASVV--WVPGFDGRAPLHSCTLQ--VA 251
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
++ ++ E ++ VQ LK T Y R++C E G S ++E T E
Sbjct 252 ESPDGQEVSTEVAPVPPFAYGVQGLKHSTNYSVRVQCSNEMGS---SPFTERVYFQTLEL 308
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA 384
PS P + I Q + L W+ + P +L Y + + V
Sbjct 309 APSSTPQNIHVI-----QRDPGLVLEWEGVAPDVLKENVLGYRLEWIQDNVTQGEMIVQD 363
Query 385 TK--LTVNLTNDRYLATLTVRNLVGKSDAA 412
TK LT + + V N G +
Sbjct 364 TKANLTTWNPLKDLIIRVCVLNSAGCGPWS 393
Score = 73.7 bits (179), Expect = 5e-12, Method: Composition-based stats.
Identities = 46/309 (15%), Positives = 86/309 (28%), Gaps = 30/309 (10%)
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
A G + S + ++ + L V+ N + + N+ G S + T+
Sbjct 150 AVGPPEPVTIVWWMGDSRVGLPDISPSILNVSGINQSTMFSCEAHNVKGLSSSRTATVQI 209
Query 419 CDFQATHPVMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDG 475
P+ + + V W R + L+ D T+
Sbjct 210 KAMP-LPPLNVTVSQVTSSNASVVWVPGFDGRAPLHSCTLQVAESPDGQEVSTEVAPVPP 268
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKGP-TVRTKKVGKN 533
+ L S Y + V G E + + PS P + +
Sbjct 269 FAYGV---QGLKHSTNYSVRVQCSNEMGSSPFTERVYFQTLELAPSSTPQNIHVIQRDPG 325
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
VLEW+ + DV + Y + + + + V + T + ++R+
Sbjct 326 -LVLEWEGVAPDVLKENVLGYRLEWIQDNVTQGEMIVQDTKANLTTWN--PLKDLIIRVC 382
Query 594 AYTDEGGKDGPEFTF----------TTPKFAQGEIEAIVVPVCLAFLLTTLLGV---LFC 640
G + P + + PV L L + V L
Sbjct 383 VLNSAGCGPWSDLFLLEAQEVMGGQRQPPYGTSWV-----PVALGILTALVTAVALALIL 437
Query 641 FNKRDLIKK 649
KR +
Sbjct 438 LRKRRKETR 446
Score = 73.4 bits (178), Expect = 7e-12, Method: Composition-based stats.
Identities = 48/288 (17%), Positives = 93/288 (32%), Gaps = 30/288 (10%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
+ PE V + N C IVW + + S +
Sbjct 131 VEPED--VSVSPNAPFH----MACAAVGPPEPVTIVWWMGD--------SRVGLPDISPS 176
Query 91 FTDIASLNIQ--LTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG 148
+++ +N +C L + T+ P P N++ W
Sbjct 177 ILNVSGINQSTMFSCEAHNVKGLSSS-RTATVQIKAMPLPPLNVTVSQVTSSNASVVWVP 235
Query 149 GRETHLET-NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV 207
G + + TL+ + P + N V V+ N +G
Sbjct 236 GFDGRAPLHSCTLQVAESPDGQEVSTEVAPVPPFAYGVQGLKHSTNYSVRVQCSNEMGSS 295
Query 208 T-SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT--NPSIKSVIILKYNIQYRTK 264
++ + F + + P N+ VI + L L W P + +L Y +++ +
Sbjct 296 PFTERVYFQTLELAPSSTPQNIHVI---QRDPGLVLEWEGVAPDVLKENVLGYRLEW-IQ 351
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
D T ++ +DT + +++ P + + R+ + G G WSD
Sbjct 352 DNVTQGEMIVQDTKANLTTW-----NPLKDLIIRVCVLNSAGCGPWSD 394
>sp|P15127|INSR_RAT Insulin receptor OS=Rattus norvegicus OX=10116
GN=Insr PE=1 SV=1
Length=1383
Score = 108 bits (268), Expect = 2e-22, Method: Composition-based stats.
Identities = 102/613 (17%), Positives = 184/613 (30%), Gaps = 134/613 (22%)
Query 228 LSVINSEELSSILKLTWTNPSIKSVI--ILKYNIQYRTK--------------DASTWSQ 271
L + L W P +L + + Y+ +++W+
Sbjct 499 LKFSFIRTSFDKILLRWE-PYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTV 557
Query 272 IPPE------DTASTRSSF---TVQDLKPFTEYVFRIR--CMKEDGKGYWSDWSEEASGI 320
+ + D S S ++ LKP+T+Y ++ D + + S+
Sbjct 558 VDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQ 617
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ-- 378
T PS + S + L WK PP + NG I Y V R +
Sbjct 618 TDATNPSVPLDPISVSNSSSQ-----IILKWK--PPSDPNGNITHYLVYWERQAEDSELF 670
Query 379 --NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-- 434
+Y + KL + + + + ++ + D + +C + + +L+
Sbjct 671 ELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASECCSCPKTDSQILKELEESSFR 730
Query 435 ------KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV----------- 477
N+++V PR++ E S K + + T
Sbjct 731 KTFEDYLHNVVFV----PRKTSSGNGAEDTRPSRKRRSLEEVGNVTATTPTLPDFPNISS 786
Query 478 ------------------HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK-QAP 518
+ + L Y I + D P + AY+ +
Sbjct 787 TIAPTSHEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERSGVAAYVSARTM 846
Query 519 PSK------GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS 572
P GP V + N L W + NG I Y + YR E + V
Sbjct 847 PEAKADDIVGP-VTHEIFENNVVHLMWQEPK--EPNGLIVLYEVSYRRYGDEELHLCVSR 903
Query 573 SH----TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF----TTPKFAQGEIEAIVVP 624
H L L+ Y VR+ A + G E T+ + I+ P
Sbjct 904 KHFALERGCRLRGLSPG-NYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGP 962
Query 625 VCLAFLLTTLLG-VLFCFNKRDLIKKHIWPNVP--------DPSKSHIAQWSPHTPPRHN 675
+ FL + ++G + KR P+ P +P + P + +
Sbjct 963 LIFVFLFSVVIGSIYLFLRKRQ-------PDGPMGPLYASSNPEYLSASDVFPSSVYVPD 1015
Query 676 FNSKDQ---------------MYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
+ M +GN D+ E+E + SL +E+I
Sbjct 1016 EWEVPREKITLLRELGQGSFGMVYEGNAKDIIKGEVETRVAVKTVNESASL----RERIE 1071
Query 721 TEGHSSGIGGSSC 733
+S + G +C
Sbjct 1072 FLNEASVMKGFTC 1084
Score = 66.0 bits (159), Expect = 2e-09, Method: Composition-based stats.
Identities = 20/127 (16%), Positives = 41/127 (32%), Gaps = 4/127 (3%)
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL---SSILKLTWTN 246
+F + ++A N + + P + V ++++ L W
Sbjct 815 HFTGYRIELQACNQDSPEERSGVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQE 874
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P + +I+ Y + YR + ++ L P Y R+R G
Sbjct 875 PKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPG-NYSVRVRATSLAG 933
Query 307 KGYWSDW 313
G W++
Sbjct 934 NGSWTEP 940
>sp|Q06418|TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3
OS=Homo sapiens OX=9606 GN=TYRO3 PE=1 SV=1
Length=890
Score = 107 bits (266), Expect = 2e-22, Method: Composition-based stats.
Identities = 73/435 (17%), Positives = 127/435 (29%), Gaps = 79/435 (18%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPK-EQYTIINRTASSVTF 91
P V C ++ + I W + + +Q I + F
Sbjct 49 PVKLTVSQGQPVKLNCSVE-------GMEEPDIQWVKDGAVVQNLDQLYIPVSEQHWIGF 101
Query 92 TDIASLNIQ----LTCNILTFGQLEQ------NVYGITII------SGLPPEKPKNLSCI 135
+ S+ C + G+ E V G+ +PP P LSC
Sbjct 102 LSLKSVERSDAGRYWCQVEDGGETEISQPVWLTVEGVPFFTVEPKDLAVPPNAPFQLSCE 161
Query 136 V---NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV 192
E + W G K P +
Sbjct 162 AVGPPEPVTIV-WWRG------------------------TTKIGGPAPSPSVLNVTGVT 196
Query 193 NIEV-WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS 251
+ EA N G +S + P P N++V ++ + W +
Sbjct 197 QSTMFSCEAHNLKGLASSRTATVHL--QALPAAPFNITVTKLSSSNASV--AWMPGADGR 252
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
++ +Q T+ W ++ + ++DL P T Y R+RC G ++
Sbjct 253 ALLQSCTVQV-TQAPGGW-EVLAVVVPVPPFTCLLRDLVPATNYSLRVRCANALGPSPYA 310
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN-GKILDYEVTL 370
DW T P+ AP + I + L W+ + P G + Y+++
Sbjct 311 DWVP---FQTKGLAPASAPQNLHAIRTDSG-----LILEWEEVIPEAPLEGPLGPYKLSW 362
Query 371 TRWKSHLQNYTVNATKLTVNLTNDRY----LATLTVRNLVGKSDAAVLTIPACDFQATHP 426
+ TV T+ NLT + + V N VG + + + +A
Sbjct 363 VQDNGTQDELTVEGTRA--NLTGWDPQKDLIVRVCVSNAVGCGPWSQPLVVSSHDRAGQ- 419
Query 427 VMDLKAFPKDNMLWV 441
+ P WV
Sbjct 420 ----QGPPHSRTSWV 430
Score = 73.0 bits (177), Expect = 9e-12, Method: Composition-based stats.
Identities = 41/266 (15%), Positives = 82/266 (31%), Gaps = 11/266 (4%)
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
EA G + R + + + + L V + + NL G + + T+
Sbjct 161 EAVGPPEPVTIVWWRGTTKIGGPAPSPSVLNVTGVTQSTMFSCEAHNLKGLASSRTATVH 220
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
A + + N V W + + +L+ C + W+ V
Sbjct 221 LQALPAAPFNITVTKLSSSNA-SVAWMP--GADGRALLQSCTV-QVTQAPGGWEVLAVVV 276
Query 478 HR---TYLRGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVGKN 533
T L +L + Y + V A GP + K P+ P +
Sbjct 277 PVPPFTCLLRDLVPATNYSLRVRCANALGPSPYADWVPFQTKGLAPASAPQNLHAIRTDS 336
Query 534 EAVLEWDQLPVDVQ-NGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+LEW+++ + G + Y + + G + + V+ + T +VR+
Sbjct 337 GLILEWEEVIPEAPLEGPLGPYKLSWVQDNGTQDELTVEGTRANLT--GWDPQKDLIVRV 394
Query 593 AAYTDEGGKDGPEFTFTTPKFAQGEI 618
G + + G+
Sbjct 395 CVSNAVGCGPWSQPLVVSSHDRAGQQ 420
>sp|P15208|INSR_MOUSE Insulin receptor OS=Mus musculus OX=10090
GN=Insr PE=1 SV=2
Length=1372
Score = 107 bits (267), Expect = 3e-22, Method: Composition-based stats.
Identities = 88/520 (17%), Positives = 161/520 (31%), Gaps = 101/520 (19%)
Query 228 LSVINSEELSSILKLTWTNPSIKSVI--ILKYNIQYRTK--------------DASTWSQ 271
L + L W P +L + + Y+ +++W+
Sbjct 500 LKFSFIRTSFDKILLRWE-PYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTV 558
Query 272 IPPE------DTASTRSSF---TVQDLKPFTEYVFRIR--CMKEDGKGYWSDWSEEASGI 320
+ + D S S ++ LKP+T+Y ++ D + + S+
Sbjct 559 VDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQ 618
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ-- 378
T PS + S + L WK PP + NG I Y V R +
Sbjct 619 TDATNPSVPLDPISVSNSSSQ-----IILKWK--PPSDPNGNITHYLVYWERQAEDSELF 671
Query 379 --NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-- 434
+Y + KL + + + + ++ + D + +C + + +L+
Sbjct 672 ELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDDSASECCSCPKTDSQILKELEESSFR 731
Query 435 ------KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT-------- 480
N+++V ++ + E ++ + D+ T+ T
Sbjct 732 KTFEDYLHNVVFV---PRPSRKRRSLEEVGNVTATTLTLPDFPNVSSTIVPTSQEEHRPF 788
Query 481 --------YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK-QAPPSK------GPTV 525
+ L Y I + D P S+ AY+ + P GP V
Sbjct 789 EKVVNKESLVISGLRHFTGYRIELQACNQDSPDERCSVAAYVSARTMPEAKADDIVGP-V 847
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH----TEYTLSS 581
+ N L W + NG I Y + YR E + V H L
Sbjct 848 THEIFENNVVHLMWQEPK--EPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRG 905
Query 582 LTSDTLYMVRMAAYTDEGGKDGPEFTF----TTPKFAQGEIEAIVVPVCLAFLLTTLLG- 636
L+ Y VR+ A + G E T+ + I+ P+ FL + ++G
Sbjct 906 LSPG-NYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIGS 964
Query 637 VLFCFNKRDLIKKHIWPNVP--------DPSKSHIAQWSP 668
+ KR P+ P +P + P
Sbjct 965 IYLFLRKRQ-------PDGPMGPLYASSNPEYLSASDVFP 997
Score = 63.7 bits (153), Expect = 7e-09, Method: Composition-based stats.
Identities = 20/127 (16%), Positives = 41/127 (32%), Gaps = 4/127 (3%)
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL---SSILKLTWTN 246
+F + ++A N + + P + V ++++ L W
Sbjct 804 HFTGYRIELQACNQDSPDERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQE 863
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P + +I+ Y + YR + ++ L P Y R+R G
Sbjct 864 PKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPG-NYSVRVRATSLAG 922
Query 307 KGYWSDW 313
G W++
Sbjct 923 NGSWTEP 929
Score = 59.1 bits (141), Expect = 2e-07, Method: Composition-based stats.
Identities = 48/330 (15%), Positives = 96/330 (29%), Gaps = 63/330 (19%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETH-------------------LETNFTLKS---- 162
P P + + N ++ +W + + E ++ LK
Sbjct 624 PSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAEDSELFELDYCLKGLKLP 683
Query 163 ---------EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN 213
+ K + C+ + + + E++ K D+++
Sbjct 684 SRTWSPPFESDDSQKHNQSEYDDSASECCSCPKTD----SQILKELEESSFRKTFEDYLH 739
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
P P + + LT P +V T ++ +
Sbjct 740 NVVFV---PRPSRKRRSLEEVGNVTATTLT--LPDFPNVS--------STIVPTSQEEHR 786
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
P + + S + L+ FT Y ++ +D + S T + A +
Sbjct 787 PFEKVVNKESLVISGLRHFTGYRIELQACNQDSPDERCSVAAYVSARTMPE----AKADD 842
Query 334 YKIDPSHTQGYRTVQ-LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN-- 390
+H V L+W+ P E NG I+ YEV+ R+ + V+ +
Sbjct 843 IVGPVTHEIFENNVVHLMWQE--PKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERG 900
Query 391 -----LTNDRYLATLTVRNLVGKSDAAVLT 415
L+ Y + +L G T
Sbjct 901 CRLRGLSPGNYSVRVRATSLAGNGSWTEPT 930
>sp|P14617|INSRR_CAVPO Insulin receptor-related protein OS=Cavia
porcellus OX=10141 GN=INSRR PE=3 SV=1
Length=1300
Score = 107 bits (266), Expect = 3e-22, Method: Composition-based stats.
Identities = 99/577 (17%), Positives = 173/577 (30%), Gaps = 100/577 (17%)
Query 230 VINSEELSSILKLTWTN-PSIKSVIILKYNIQYRT--------------KDASTWSQIPP 274
V N E IL L W +++ +L + + Y+ + +W+ +
Sbjct 490 VSNVTEADRIL-LRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGSQSWNLLDV 548
Query 275 EDTASTRSS--FTVQDLKPFTEYVFRIRCMK------EDGKGYWSDWSEEASGITYEDRP 326
E S + LKP+T+Y +R + +G S T P
Sbjct 549 ELPLSRTQEPGVILAPLKPWTQYAVFVRAITLTTAEDSPHQGAQ---SPIVYLWTLPAAP 605
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS----HLQNYTV 382
+ S + + + WK PP + NG I Y V R +L +Y
Sbjct 606 TVPQDV-----ISSSNSSSHLLVRWK--PPTQRNGNITYYLVLWQRLAEDGDLYLNDYCH 658
Query 383 NATKLTV---NLTNDRYLATLTVRNLVGKSD----AAVLTIPACDFQATHPVMDLKAF-- 433
+L + DR L +G +PA + Q + F
Sbjct 659 RGLRLPTSNHDPRFDREDGDLEAELELGCCPCQHAPPGQVLPALEAQEASFQKKFENFLH 718
Query 434 -------PKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
P + + R++ + + Q++ R L G L
Sbjct 719 NAITIPKPPWKVTSIHRNLQRDAGRHRRAIGSPRPGGNSSDFEIQEDKVPRERAVL-GGL 777
Query 487 AESKCYLITVTPVYADG--PGSPESIKAYLKQAPPSK-----GPTVRTKKVGKNEAVLEW 539
Y I + G + + + P + + + K+ +L W
Sbjct 778 RHFTEYRIDIHACNHAAHIVGCSAATFVFA-RTMPRREADDIPGKLSWEAASKSSVLLRW 836
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS----LTSDTLYMVRMAAY 595
+ P NG I Y I YR + T + V S + L Y R+ A
Sbjct 837 FEPP--DPNGLILKYEIKYRRLGEEATVLCV-SRLRYAKVGGVQLALLPPGNYSARVRAT 893
Query 596 TDEGGK----------DGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRD 645
+ G GPE I V P L L+ F KR+
Sbjct 894 SLAGNGSWTDSVAFYIPGPEEE----DSGGLHILLTVTPAGLMLLIILAALGFFYSRKRN 949
Query 646 LIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQM-----YSDGNFTDVSVVEIE--A 698
++ +V +P + P ++Q+ G+F V +
Sbjct 950 ---GTLYTSV-NPEYLSASDMY---IPDEWEVPREQISIIRELGQGSFGMVYEGVAKGLE 1002
Query 699 NDKKPFPEDLKSLD--LFKKEKINTEGHSSGIGGSSC 733
++ P LK+++ +E+I +S + C
Sbjct 1003 AGEESTPVALKTVNELASPRERIEFLKEASVMKAFQC 1039
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 61/356 (17%), Positives = 104/356 (29%), Gaps = 63/356 (18%)
Query 191 FVNIEVWVEAENALGKVTS------DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ V+V A S I + P P + VI+S SS L + W
Sbjct 568 WTQYAVFVRAITLTTAEDSPHQGAQSPIVYLWTLPAAPTVPQD--VISSSNSSSHLLVRW 625
Query 245 TNPSIKSVIILKYNIQYR---------TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
P+ ++ I Y + ++ D P R DL+ E
Sbjct 626 KPPTQRNGNITYYLVLWQRLAEDGDLYLNDYCHRGLRLPTSNHDPRFDREDGDLEAELE- 684
Query 296 VFRIRCMK----EDGKGYWSDWSEEASG-----------ITYEDRPSKAPSFWYKIDPSH 340
+ C G+ + ++EAS IT P K S +
Sbjct 685 ---LGCCPCQHAPPGQVLPALEAQEASFQKKFENFLHNAITIPKPPWKVTSIHRNLQRDA 741
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL 400
+ R + P N + ++ L Y +
Sbjct 742 GRHRRAI-----GSPRPGGNS---------SDFEIQEDKVPRERAVLGGLRHFTEYRIDI 787
Query 401 TVRN----LVGKSDAAVL---TIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES---V 450
N +VG S A + T+P + + +A K + + + W P + +
Sbjct 788 HACNHAAHIVGCSAATFVFARTMPRREADDIPGKLSWEAASKSS-VLLRWFEPPDPNGLI 846
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
KY +++ L ++A + + V L L Y V G GS
Sbjct 847 LKYEIKYRRLGEEATVLCVSRLRYAKVGGVQLA--LLPPGNYSARVRATSLAGNGS 900
>sp|Q00872|MYPC1_HUMAN Myosin-binding protein C, slow-type OS=Homo
sapiens OX=9606 GN=MYBPC1 PE=1 SV=2
Length=1141
Score = 106 bits (265), Expect = 4e-22, Method: Composition-based stats.
Identities = 68/439 (15%), Positives = 122/439 (28%), Gaps = 60/439 (14%)
Query 197 WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIIL 255
+ +N G+ H + P+PP +V +E + W P+ IL
Sbjct 598 HINLKNEAGEA---HASIKVKVVDFPDPPVAPTV--TEVGDDWCIMNWEPPAYDGGSPIL 652
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y I+ + K +S W ++ + ++F + + Y RI + G S S
Sbjct 653 GYFIERKKKQSSRWMRLNFDLC--KETTFEPKKMIEGVAYEVRIFAVNAIGI---SKPSM 707
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
+ S P+ + T TV + W+ A G + Y + S
Sbjct 708 PSRPFVPLAVTS-PPTLLTVDSVTDT----TVTMRWRPPDHIGAAG-LDGYVLEYCFEGS 761
Query 376 HLQNYTVNATKLTVNLTNDRYLA------------------------TLTVRNLVGKSDA 411
+ + +L + ++ + N G S+
Sbjct 762 TSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP 821
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
+ P + P E+V I K W+
Sbjct 822 KYYSQPILVKEIIEPPKIRIPRHLKQTYI---RRVGEAVNLVI----PFQGKPRPELTWK 874
Query 472 QEDGTVHRTYL-RGNLAESKCYLITVTPVYADG-PGSPESIKAYLKQA--------PPSK 521
++ + + + N I G + +++ A P
Sbjct 875 KDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP 934
Query 522 GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDSSHTEYTLS 580
V+ + V L W P D N I YTI V T T++
Sbjct 935 PQIVKIEDVWGENVALTWTP-PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATIT 993
Query 581 SLTSDTLYMVRMAAYTDEG 599
L Y R+ + G
Sbjct 994 ELVIGNEYYFRVFSENMCG 1012
Score = 88.4 bits (217), Expect = 2e-16, Method: Composition-based stats.
Identities = 72/538 (13%), Positives = 145/538 (27%), Gaps = 73/538 (14%)
Query 30 YISPESPVVQLHSNFTAVCVLKEKCM-----DYFHVNANYIVWKTNHFTIPK-------E 77
++ ++ + + +W I + E
Sbjct 517 HVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
Query 78 QYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLS---- 133
Y + + D + + N V + PP P
Sbjct 577 SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP--DPPVAPTVTEVGDD 634
Query 134 -CIVNEGKKMRCEWDGGRETH--------LETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
CI+N W+ +E S W F CK P
Sbjct 635 WCIMN--------WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEP----- 681
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ V EV + A NA+G + V +PP L+V + + + + W
Sbjct 682 -KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSV--TDTTVTMRW 738
Query 245 TNPSIKSVIIL-KYNIQYRTKDASTWSQIPPEDTAS----------------TRSSFTVQ 287
P L Y ++Y + +++ Q A+ ++ FT+
Sbjct 739 RPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTIT 798
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSFWYKIDPSHTQGYRT 346
L + R++ + G +S+ + P + P +
Sbjct 799 GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVN 858
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRY--LATLTVRN 404
+ + ++ P E K E+ + T + + + L V+
Sbjct 859 LVIPFQGKPRPELTWKKDGAEI---DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKV 915
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
+ A + I D ++ ++ +N + + WT P++ I + +
Sbjct 916 DKF-VETASIDIQIIDRPGPPQIVKIEDVWGEN-VALTWTPPKDDGNAAITGYTIQKADK 973
Query 465 PCITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
+W HRT L Y V G ++ K++
Sbjct 974 KS-MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATM---TKESAVIA 1027
Score = 76.0 bits (185), Expect = 1e-12, Method: Composition-based stats.
Identities = 40/250 (16%), Positives = 85/250 (34%), Gaps = 28/250 (11%)
Query 377 LQNYTVNATKLT-VNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK 435
++Y ++T + + +D + + ++N G+ A + + DF +
Sbjct 575 TESYPDSSTLVIDIAERDDSGVYHINLKNEAGE-AHASIKVKVVDFPDPPVAPTVTEVGD 633
Query 436 DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQE--DGTVHRTYLRGNLAESKCYL 493
D + + W P IL + + K + W + D T+ + E Y
Sbjct 634 DWCI-MNWEPPAYDGGSPILGYFI-ERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 691
Query 494 ITVTPVYADGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
+ + V A G P + ++ A S + V + W P + +
Sbjct 692 VRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRP-PDHIGAAGLD 750
Query 553 NYTIFY---------RTIIGNETAVNVDSS-----------HTEYTLSSLTSDTLYMVRM 592
Y + Y ++ E A ++ + T++T++ L +D VR+
Sbjct 751 GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 810
Query 593 AAYTDEGGKD 602
A G +
Sbjct 811 KAVNAAGASE 820
>sp|P35822|PTPRK_MOUSE Receptor-type tyrosine-protein phosphatase
kappa OS=Mus musculus OX=10090 GN=Ptprk PE=1 SV=1
Length=1457
Score = 106 bits (263), Expect = 7e-22, Method: Composition-based stats.
Identities = 64/500 (13%), Positives = 140/500 (28%), Gaps = 43/500 (9%)
Query 95 ASLNIQLTCNILTFGQLEQNVYGITIISGLPPEK-P-----KNLSCIVNEGKKMRCEWDG 148
+ + + I ++S P +K P ++ + +C
Sbjct 161 NEYQVIFEAEVSGGRSGYIAIDDIQVLS-YPCDKSPHFLRLGDVEVNAGQNATFQC-IAT 218
Query 149 GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
GR+ + + A K + + V + +++ + + +
Sbjct 219 GRDAVHNKLWLQRRNGEDIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSE-RGS 277
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST 268
+ + P P ++ +++L N I I+ ++YR + +
Sbjct 278 GVSNFAQLIVREPPRPIAPPQLLGVGPTYLLIQLN-ANSIIGDGPIILKEVEYRM-TSGS 335
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
W++ + ++ + L P TEY R+ + G+G T P +
Sbjct 336 WTETHAVNA----PTYKLWHLDPDTEYEIRVL-LTRPGEGGTGLPGPPLITRTKCAEPMR 390
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ------NYTV 382
P + R + + W++L + + ++ H + +
Sbjct 391 TPKTLKIAEIQA----RRIAVDWESLGYNITRCHTFNVTICYHYFRGHNESRADCLDMDP 446
Query 383 NATKLTVN--LTNDRYLATLTVRNLVG-KSDAAVLTIPACDFQATHPVMDLKAFPKDNML 439
A + VN + + N G K + D PV L+ +N +
Sbjct 447 KAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDEDVPGPVPVKSLQGTSFENKI 506
Query 440 WVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT--------YLRGNLAESKC 491
++ W P E I ++ V G ++ +L
Sbjct 507 FLNWKEPLEP-NGIITQYEVSYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTT 565
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT---KKVGKNEAVLEWDQLPVDVQN 548
Y + G G +I + PS + P +
Sbjct 566 YQFFIRASTVKGFGPATAINVTTNISAPSLPDYEGVDASLNETATTITV--LLRPAQAKG 623
Query 549 GFIRNYTIFYRTIIGNETAV 568
I Y I + + T
Sbjct 624 APISAYQIVVEQLHPHRTKR 643
Score = 77.2 bits (188), Expect = 5e-13, Method: Composition-based stats.
Identities = 63/366 (17%), Positives = 109/366 (30%), Gaps = 42/366 (11%)
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSK-APSFWYKIDPSH---TQGYRTVQLVWKTLP 355
RC+ + +G S S A I E P AP + P++ ++
Sbjct 268 RCVTQSERG--SGVSNFAQLIVRE-PPRPIAPPQLLGVGPTYLLIQLNANSII------- 317
Query 356 PFEANGKILDYEVTLTRWKSHL-QNYTVNAT--KLTVNLTNDRYLATLTVR----NLVGK 408
+G I+ EV + + VNA KL + Y + + G
Sbjct 318 ---GDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLTRPGEGGTGL 374
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK-----KYILEWCVLSDK 463
++T C P A + + V+W + ++ + +
Sbjct 375 PGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFRGH 434
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
D D ++ +L + + +G E + P P
Sbjct 435 NESRADCLDMDPKA-PQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDEDVPGPVP 493
Query 524 TVRTKKVG-KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS---------S 573
+ +N+ L W + NG I Y + Y +I + AV V +
Sbjct 494 VKSLQGTSFENKIFLNWKE--PLEPNGIITQYEVSYSSIRSFDPAVPVAGPPQTVSNLWN 551
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTT 633
T + L T Y + A T +G TT A + V L TT
Sbjct 552 STHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNISAPSLPDYEGVDASLNETATT 611
Query 634 LLGVLF 639
+ +L
Sbjct 612 ITVLLR 617
>sp|P55144|TYRO3_MOUSE Tyrosine-protein kinase receptor TYRO3
OS=Mus musculus OX=10090 GN=Tyro3 PE=1 SV=2
Length=880
Score = 105 bits (262), Expect = 7e-22, Method: Composition-based stats.
Identities = 65/428 (15%), Positives = 118/428 (28%), Gaps = 76/428 (18%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPK-EQYTIINRTASSVTF 91
P V C ++ + I W + + Q +I S +
Sbjct 39 PVKMTVSQGQPVKLNCSVE-------GMEDPDIHWMKDGTVVQNASQVSISISEHSWIGL 91
Query 92 TDIASLNIQLTCNILTFGQLEQN----------VYGITII------SGLPPEKPKNLSCI 135
+ S+ + + V G+ +PP P LSC
Sbjct 92 LSLKSVERSDAGLYWCQVKDGEETKISQSVWLTVEGVPFFTVEPKDLAVPPNAPFQLSCE 151
Query 136 V---NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV 192
E + W G K P +
Sbjct 152 AVGPPEPVTIY-WWRG------------------------LTKVGGPAPSPSVLNVTGVT 186
Query 193 N-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS 251
E EA N G TS + P P N +V ++ + W +
Sbjct 187 QRTEFSCEARNIKGLATSRPAIVRL--QAPPAAPFNTTVTTISSYNASV--AWVPGADGL 242
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
++ +Q W + + +++L P T Y R+RC G +
Sbjct 243 ALLHSCTVQV-AHAPGEWEALAVVVPVPP-FTCLLRNLAPATNYSLRVRCANALGPSPYG 300
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA-NGKILDYEVTL 370
DW T P++AP ++ I + L W+ + P + G + Y+++
Sbjct 301 DWVP---FQTKGLAPARAPQNFHAIRTDSG-----LILEWEEVIPEDPGEGPLGPYKLSW 352
Query 371 TRWKSHLQNYTVNATKLTVNLTNDRY----LATLTVRNLVGKSDAAVLTIPACDFQAT-- 424
+ V T+ NLT+ + + N +G + + + A
Sbjct 353 VQENGTQDELMVEGTRA--NLTDWDPQKDLILRVCASNAIGDGPWSQPLVVSSHDHAGRQ 410
Query 425 HPVMDLKA 432
P +
Sbjct 411 GPPHSRTS 418
Score = 73.0 bits (177), Expect = 9e-12, Method: Composition-based stats.
Identities = 49/257 (19%), Positives = 87/257 (34%), Gaps = 17/257 (7%)
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG--KSDAAVLT 415
EA G + R + + + + L V R + RN+ G S A++
Sbjct 151 EAVGPPEPVTIYWWRGLTKVGGPAPSPSVLNVTGVTQRTEFSCEARNIKGLATSRPAIVR 210
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ---Q 472
+ A + + + ++ WV P + V AP +W+
Sbjct 211 LQAPPAAPFNTTVTTISSYNASVAWV----PGADGLALLHSCTVQVAHAPG--EWEALAV 264
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVG 531
T L NLA + Y + V A GP + K P++ P
Sbjct 265 VVPVPPFTCLLRNLAPATNYSLRVRCANALGPSPYGDWVPFQTKGLAPARAPQNFHAIRT 324
Query 532 KNEAVLEWDQL-PVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMV 590
+ +LEW+++ P D G + Y + + G + + V+ + T ++
Sbjct 325 DSGLILEWEEVIPEDPGEGPLGPYKLSWVQENGTQDELMVEGTRANLT--DWDPQKDLIL 382
Query 591 RMAAYTDEGGKDGPEFT 607
R+ A G DGP
Sbjct 383 RVCASNAIG--DGPWSQ 397
Score = 51.4 bits (121), Expect = 4e-05, Method: Composition-based stats.
Identities = 66/431 (15%), Positives = 117/431 (27%), Gaps = 65/431 (15%)
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD--KAPC 466
S + LT+ F P A P + + I W L+
Sbjct 118 SQSVWLTVEGVPFFTVEPKD--LAVPPNAPFQLSCEAVGPPEPVTIYWWRGLTKVGGPAP 175
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVR 526
G RT + G + L+ APP+
Sbjct 176 SPSVLNVTGVTQRT------------EFSCEARNIKGLATSRPAIVRLQ-APPAAPFNTT 222
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA--VNVDSSHTEYTLSSLTS 584
+ A + W +P + + T+ G A V V L +L
Sbjct 223 VTTISSYNASVAW--VPGADGLALLHSCTVQVAHAPGEWEALAVVVPVPPFTCLLRNLAP 280
Query 585 DTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNK 643
T Y +R+ G G F T A P + T +L
Sbjct 281 ATNYSLRVRCANALGPSPYGDWVPFQTKGLAPAR-----APQNFHAIRTDSGLILE---- 331
Query 644 RDLIKKHIWPNVP-----DPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEA 698
+ + P P P K Q + ++ + D+ + +
Sbjct 332 ----WEEVIPEDPGEGPLGPYKLSWVQENGTQDELMVEGTRANLTDWDPQKDLILRVCAS 387
Query 699 NDKKPFPED----LKSLDLFKKEKINTEGHS--SGIGGSSCMSSSRPSISSSDENESSQN 752
N P + S D ++ S + G + +++ + +
Sbjct 388 NAIGDGPWSQPLVVSSHDHAGRQGPPHSRTSWVPVVLGVLTALITAAALALILLRKRRKE 447
Query 753 TSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQ-LVDHVDGGDG---- 807
T ++ S P+V F + S + ERPE ++ +D + D
Sbjct 448 T----RFGQAFDSVMARGEPAV-HFRAARSF-----NRERPERIEATLDSLGISDELKEK 497
Query 808 ----ILPRQQY 814
++P QQ+
Sbjct 498 LEDVLIPEQQF 508
>sp|Q9Z2I4|ROBO3_MOUSE Roundabout homolog 3 OS=Mus musculus OX=10090
GN=Robo3 PE=1 SV=3
Length=1402
Score = 105 bits (262), Expect = 9e-22, Method: Composition-based stats.
Identities = 82/550 (15%), Positives = 161/550 (29%), Gaps = 71/550 (13%)
Query 30 YISPESPVVQLHSNFTAVCVLKEKCMDYFHVNAN--YIVWKTNHFTIPKEQYTIINRTAS 87
P++ V +N + C K ++ + P + + R
Sbjct 350 VTKPQNQTVAPGANVSFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPMGRLLVSPRGQL 409
Query 88 SVTFTDIASLNIQLTCNILTFGQLEQ----NVYGITIISGLPP---EKPKNLSCIVNEGK 140
++T I + + G + + G +I GLPP + P N + ++
Sbjct 410 NITEVKIGDGGYYVCQAVSVAGSILAKALLEIKGASID-GLPPIILQGPANQTLVLGSSV 468
Query 141 KMRCE----------------WDGGRET--HLETNFTLKSEWATHKFADCKAKRDTPTSC 182
+ C W G ++ +L N TL A + SC
Sbjct 469 WLPCRVIGNPQPNIQWKKDERWLQGDDSQFNLMDNGTLH-------IASIQEMDMGFYSC 521
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
V S++ W+ + G I +E ++ + L
Sbjct 522 -VAKSSIGEATWNSWLRKQEDWGASPGPATGPSNPPG------PPSQPIVTEVTANSITL 574
Query 243 TWTNPSIKSVIILKYNIQ-YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
TW Y I+ + +TW + ++T+ L+P T Y+F +R
Sbjct 575 TWKPNPQSGATATSYVIEAFSQAAGNTWRTVAD---GVQLETYTISGLQPNTIYLFLVRA 631
Query 302 MKEDGKGYWSDWSEEASGI-TYEDRPSKAP--------SFWYKIDPSHTQGYRTVQLVWK 352
+ G S SE + RP++ P ++ G RT+Q+ W
Sbjct 632 VGAWGLSEPSPVSEPVQTQDSSLSRPAEDPWKGQRGLAEVAVRMQEPTVLGPRTLQVSWT 691
Query 353 TLPPFEANGKILDYEVTLT-------RWKSHLQNYTVNATKLTVNLTNDRYL-ATLTVRN 404
P + + + V+ W + + L + + V+
Sbjct 692 VDGPVQ---LVQGFRVSWRIAGLDQGSWTMLDLQSPHKQSTVLRGLPPGAQIQIKVQVQG 748
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFP----KDNMLWVEWTTPRESVKKYIL-EWCV 459
G + + +A A +++ + V W P S + ++ E+ +
Sbjct 749 QEGLGAESPFVTRSIPEEAPSGPPQGVAVALGGDRNSSVTVSWEPPLPSQRNGVITEYQI 808
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
+ R+ L + Y V + G G + PP
Sbjct 809 WCLGNESRFHLNRSAAGWARSVTFSGLLPGQIYRALVAAATSAGVGVASAPVLVQLPFPP 868
Query 520 SKGPTVRTKK 529
+ P +
Sbjct 869 AAEPGPEVSE 878
Score = 100 bits (248), Expect = 5e-20, Method: Composition-based stats.
Identities = 96/620 (15%), Positives = 179/620 (29%), Gaps = 84/620 (14%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P + VV + +C ++ + W+ + +P +Y I R+ S+
Sbjct 264 PINQVVLADAPVNFLCEVQ-------GDPQPNLHWRKDDGELPAGRYEI--RSDHSLWID 314
Query 93 DIASLNIQ-LTCNILTFGQLEQNVYGITIISGLPP---EKPKNLSCIVNEGKKMRCEWDG 148
++S + TC + ++ +PP KP+N + +CE G
Sbjct 315 QVSSEDEGTYTCVAENSVGRAEA--SGSLSVHVPPQFVTKPQNQTVAPGANVSFQCETKG 372
Query 149 GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV--------EA 200
+ + + ++ P + EV + +A
Sbjct 373 NPPPAI------FWQKEGSQVLLFPSQSLQPMGRLLVSPRGQLNITEVKIGDGGYYVCQA 426
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLS--VINSEELSSILKLTWTNPSIKSVIILKYN 258
+ G + + + + PP L + L S + L N
Sbjct 427 VSVAGSILAKALLEIKGASIDGLPPIILQGPANQTLVLGSSVWLPCRVIGNPQP-----N 481
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
IQ++ KD + + + ++ + G+ W+ W
Sbjct 482 IQWK-KDERWLQGDDSQFNLMDNGTLHIASIQEMDMGFYSCVAKSSIGEATWNSW--LRK 538
Query 319 GITYEDRPSKAPSFWYKIDPS-----HTQGYRTVQLVWKTLPPFEANGKILDYEV-TLTR 372
+ P A P ++ L WK P A Y + ++
Sbjct 539 QEDWGASPGPATGPSNPPGPPSQPIVTEVTANSITLTWKPNPQSGA--TATSYVIEAFSQ 596
Query 373 WKSHLQNYTVNATKLTVNL-----TNDRYLATLTVRNLVGKSDAAVLTIPACD------- 420
+ + +L N YL + G S+ + ++ P
Sbjct 597 AAGNTWRTVADGVQLETYTISGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVQTQDSSLSR 656
Query 421 -----------FQATHPVMDLKAFPKDNMLWVEWTT--PRESVKKYILEWCVLSDKAPCI 467
M L V WT P + V+ + + W +
Sbjct 657 PAEDPWKGQRGLAEVAVRMQEPTVLGPRTLQVSWTVDGPVQLVQGFRVSWRIAGLDQGSW 716
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL-KQAPPSKGPTVR 526
T + T LRG L I V +G G+ + PS P
Sbjct 717 TMLDLQSPHKQSTVLRG-LPPGAQIQIKVQVQGQEGLGAESPFVTRSIPEEAPSGPPQGV 775
Query 527 TKKVG---KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSS----HTEYTL 579
+G + + W+ +NG I Y I+ +GNE+ +++ S T
Sbjct 776 AVALGGDRNSSVTVSWEPPLPSQRNGVITEYQIW---CLGNESRFHLNRSAAGWARSVTF 832
Query 580 SSLTSDTLYMVRMAAYTDEG 599
S L +Y +AA T G
Sbjct 833 SGLLPGQIYRALVAAATSAG 852
>sp|Q9PVZ4|INSR_XENLA Insulin receptor OS=Xenopus laevis OX=8355
GN=insr PE=1 SV=1
Length=1362
Score = 105 bits (262), Expect = 1e-21, Method: Composition-based stats.
Identities = 78/480 (16%), Positives = 140/480 (29%), Gaps = 75/480 (16%)
Query 228 LSVINSEELSSILKLTWT---NPSIKSVIILKYNIQYRTK--------------DASTWS 270
L+ + ++ L W P + +L + + Y+ +++W+
Sbjct 510 LTFNFIKTSHDMVLLRWDAYWPPDYRD--LLGFMVHYKEAPFQNVTEFDGQDACGSNSWT 567
Query 271 QIP---PEDTASTRSS---FTVQDLKPFTEYVFRIR--CMKEDGKGYWSDWSEEASGITY 322
+ PE +A ++ ++ LKP+T+Y ++ D + S+ T
Sbjct 568 VVDMDAPERSADGKTQSPGCLLRSLKPWTQYAVFVKTLVSGSDEGRTYGAKSKIIYIRTN 627
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
E PS + + + + L WK PP E NG + Y V Y V
Sbjct 628 ETIPSVPLDPFSVSNSTSQ-----IILKWK--PPSEPNGNVTHYLVYWQEQPEDSDLYEV 680
Query 383 NATKLTVNLTNDRYLATLTV-RNLVGKSDAAVLTIPACDFQAT----HPVMDLKAFPKD- 436
+ + L + + + N C T D AF K
Sbjct 681 DYCNKGLKLPSRTWTPPTEIDENGNENQTEHTSVNKCCPCPKTEFQIQKEQDESAFRKTF 740
Query 437 -----NMLWVEWT---------------TPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
N +++ + + P + Q+
Sbjct 741 ENYLHNEVFIPRPVRKRRDLFGVANGTLPDPVTAPPLFNVSSTRAPDEPEPKIYSQKVWF 800
Query 477 VHRTYLRGNLAESKCYLITVTPVYAD---GPGSPESIKAYL--KQAPPSKGPTVRTKKVG 531
+ G L Y I + + G + A + + + V
Sbjct 801 KESVLISG-LKHFTGYRIEIHACNHELSMGCSVAAYVNARTMPEATADKVVGPITYEYVE 859
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS-----LTSDT 586
N L+W + NG I Y + Y + G E + S T LT
Sbjct 860 PNIIHLKWQEPK--DPNGLIVLYEVHYSRVGGIEEVITCVSQKQYNTDKGGKLRVLTPG- 916
Query 587 LYMVRMAAYTDEGGKDGPEFT-FTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRD 645
Y V++ A + G E F P I I+ +A L ++ V K+
Sbjct 917 NYSVKIRATSLAGNGSWTEQAYFQVPDHPHSNIVKIITGPIIAVFLLLIVLVYCVVQKKK 976
Score = 59.1 bits (141), Expect = 2e-07, Method: Composition-based stats.
Identities = 24/153 (16%), Positives = 46/153 (30%), Gaps = 18/153 (12%)
Query 170 ADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN-ALGKVTSDHINFDPVYKVKPNPPHNL 228
+++ + +F + + A N L S + + P +
Sbjct 791 PKIYSQKVWFKESVLISGLKHFTGYRIEIHACNHELSMGCSVAAYVNA--RTMPEATADK 848
Query 229 SVINSE---ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
V +I+ L W P + +I+ Y + Y I T ++ +
Sbjct 849 VVGPITYEYVEPNIIHLKWQEPKDPNGLIVLYEVHYSRVGG-----IEEVITCVSQKQYN 903
Query 286 VQD------LKPFTEYVFRIRCMKEDGKGYWSD 312
L P Y +IR G G W++
Sbjct 904 TDKGGKLRVLTPG-NYSVKIRATSLAGNGSWTE 935
>sp|Q60751|IGF1R_MOUSE Insulin-like growth factor 1 receptor OS=Mus
musculus OX=10090 GN=Igf1r PE=1 SV=3
Length=1373
Score = 105 bits (261), Expect = 1e-21, Method: Composition-based stats.
Identities = 69/487 (14%), Positives = 151/487 (31%), Gaps = 88/487 (18%)
Query 228 LSVINSEELSSILKLTW---TNPSIKSVIILKYNIQYRTK--------------DASTWS 270
L ++ + + +TW P + ++ + + Y+ +++W+
Sbjct 494 LRFTSTTTWKNRIIITWHRYRPPDYRD--LISFTVYYKEAPFKNVTEYDGQDACGSNSWN 551
Query 271 QIPPEDTASTRSS--FTVQDLKPFTEYVFRIRCM------KEDGKGYWSDWSEEASGITY 322
+ + + + LKP+T+Y ++ + + +G SE T
Sbjct 552 MVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGA---KSEILYIRTN 608
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
PS S + + + W PP NG + Y V R Y
Sbjct 609 ASVPSIPLDVL-----SASNSSSQLIVKWN--PPTLPNGNLSYYIVRWQRQPQDGYLYRH 661
Query 383 N-ATKLTVNLTNDR-YLATLTVRNLVGKSD------------AAVLTIPACDFQATHPVM 428
N +K + + + K++ + +
Sbjct 662 NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYRK 721
Query 429 DLKAFPKDNMLWVEWTTPRESVKK-------------YILEWCVLSDKAPCITDW---QQ 472
+ F +++ R V + + + ++D T++ +
Sbjct 722 VFENFLHNSIFVPRPERRRRDVMQVANTTMSSRSRNTTVADTYNITDPEEFETEYPFFES 781
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYAD----GPGSPESIKAYL--KQAPPSKGPTVR 526
RT + NL Y I + + G + + A + V
Sbjct 782 RVDNKERTVI-SNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT 840
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY---TLSSLT 583
+ +N L+W + + NG I Y I Y + + ++ + +Y L+ L
Sbjct 841 WEPRPENSIFLKWPE--PENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLN 898
Query 584 SDTLYMVRMAAYTDEGGKDGPEF---TFTTP---KFAQGEIEAIVVPVCLAFLLTTLLGV 637
Y R+ A + G +G F P + I +PV + ++ L+ +
Sbjct 899 PG-NYTARIQATSLSG--NGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIM 955
Query 638 LFCFNKR 644
L+ F+++
Sbjct 956 LYVFHRK 962
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 30/175 (17%), Positives = 53/175 (30%), Gaps = 15/175 (9%)
Query 147 DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN---- 202
R T + + + R TV + F + + + N
Sbjct 753 SRSRNTTVADTYNITDPEEFETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAE 812
Query 203 ALGKVTSDHINFDPV----YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
LG S+ + + P P V + + L W P + +IL Y
Sbjct 813 KLGCSASNFVFARTMPAEGADDIPGP-----VTWEPRPENSIFLKWPEPENPNGLILMYE 867
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
I+Y ++ + ++ + L P Y RI+ G G W+D
Sbjct 868 IKYGSQVEDQRECVSRQE-YRKYGGAKLNRLNPG-NYTARIQATSLSGNGSWTDP 920
Score = 40.2 bits (92), Expect = 0.10, Method: Composition-based stats.
Identities = 17/77 (22%), Positives = 34/77 (44%), Gaps = 6/77 (8%)
Query 191 FVNIEVWVEAENALGKVTSDHIN-----FDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ V+V+A L V +DHI + P L V+++ SS L + W
Sbjct 575 WTQYAVYVKAVT-LTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWN 633
Query 246 NPSIKSVIILKYNIQYR 262
P++ + + Y ++++
Sbjct 634 PPTLPNGNLSYYIVRWQ 650
>sp|Q15262|PTPRK_HUMAN Receptor-type tyrosine-protein phosphatase
kappa OS=Homo sapiens OX=9606 GN=PTPRK PE=1 SV=2
Length=1439
Score = 105 bits (261), Expect = 1e-21, Method: Composition-based stats.
Identities = 58/500 (12%), Positives = 136/500 (27%), Gaps = 43/500 (9%)
Query 95 ASLNIQLTCNILTFGQLEQNVYGITIISGLPPEK-P-----KNLSCIVNEGKKMRCEWDG 148
+ + + I ++S P +K P ++ + +C
Sbjct 162 NEYQVIFEAEVSGGRSGYIAIDDIQVLS-YPCDKSPHFLRLGDVEVNAGQNATFQC-IAT 219
Query 149 GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
GR+ + + A K + + V + +++ + + +
Sbjct 220 GRDAVHNKLWLQRRNGEDIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSE-RGS 278
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST 268
+ + P P ++ +++L N I I+ ++YR + +
Sbjct 279 GVSNFAQLIVREPPRPIAPPQLLGVGPTYLLIQLN-ANSIIGDGPIILKEVEYRM-TSGS 336
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
W++ + ++ + L P TEY R+ + G+G T P +
Sbjct 337 WTETHAVNA----PTYKLWHLDPDTEYEIRVL-LTRPGEGGTGLPGPPLITRTKCAEPMR 391
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV------ 382
P + R + + W++L + + ++ H ++
Sbjct 392 TPKTLKIAEIQA----RRIAVDWESLGYNITRCHTFNVTICYHYFRGHNESKADCLDMDP 447
Query 383 --NATKLTVNLTNDRYLATLTVRNLVG-KSDAAVLTIPACDFQATHPVMDLKAFPKDNML 439
+ + + N G K + D PV L+ +N +
Sbjct 448 KAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDEDVPGPVPVKSLQGTSFENKI 507
Query 440 WVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT--------YLRGNLAESKC 491
++ W P I ++ + G ++ +L
Sbjct 508 FLNWKEPL-DPNGIITQYEISYSSIRSFDPAVPVAGPPQTVSNLWNSTHHVFMHLHPGTT 566
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT---KKVGKNEAVLEWDQLPVDVQN 548
Y + G G +I + P+ + P +
Sbjct 567 YQFFIRASTVKGFGPATAINVTTNISAPTLPDYEGVDASLNETATTITV--LLRPAQAKG 624
Query 549 GFIRNYTIFYRTIIGNETAV 568
I Y I + + T
Sbjct 625 APISAYQIVVEELHPHRTKR 644
Score = 76.4 bits (186), Expect = 1e-12, Method: Composition-based stats.
Identities = 64/366 (17%), Positives = 109/366 (30%), Gaps = 42/366 (11%)
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSK-APSFWYKIDPSH---TQGYRTVQLVWKTLP 355
RC+ + +G S S A I E P AP + P++ ++
Sbjct 269 RCVTQSERG--SGVSNFAQLIVRE-PPRPIAPPQLLGVGPTYLLIQLNANSII------- 318
Query 356 PFEANGKILDYEVTLTRWKSHL-QNYTVNAT--KLTVNLTNDRYLATLTVR----NLVGK 408
+G I+ EV + + VNA KL + Y + + G
Sbjct 319 ---GDGPIILKEVEYRMTSGSWTETHAVNAPTYKLWHLDPDTEYEIRVLLTRPGEGGTGL 375
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK-----KYILEWCVLSDK 463
++T C P A + + V+W + ++ + +
Sbjct 376 PGPPLITRTKCAEPMRTPKTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYHYFRGH 435
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
D D ++ +L + + +G E + P P
Sbjct 436 NESKADCLDMDPKA-PQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDEDVPGPVP 494
Query 524 TVRTKKVG-KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS---------S 573
+ +N+ L W + NG I Y I Y +I + AV V +
Sbjct 495 VKSLQGTSFENKIFLNWKE--PLDPNGIITQYEISYSSIRSFDPAVPVAGPPQTVSNLWN 552
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTT 633
T + L T Y + A T +G TT A + V L TT
Sbjct 553 STHHVFMHLHPGTTYQFFIRASTVKGFGPATAINVTTNISAPTLPDYEGVDASLNETATT 612
Query 634 LLGVLF 639
+ +L
Sbjct 613 ITVLLR 618
Score = 47.5 bits (111), Expect = 6e-04, Method: Composition-based stats.
Identities = 73/435 (17%), Positives = 129/435 (30%), Gaps = 63/435 (14%)
Query 394 DRYLATLTVRNLVGKS------DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
+ Y G+S D VL+ P + D++ N + T R
Sbjct 162 NEYQVIFEAEVSGGRSGYIAIDDIQVLSYPCDKSPHFLRLGDVEVNAGQNATFQCIATGR 221
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD---GP 504
++V + + I Q ++ R L E + G
Sbjct 222 DAVHNKL---WLQRRNGEDIPVAQTKNINHRRFAASFRLQEVTKTDQDLYRCVTQSERGS 278
Query 505 GSPESIKAYLKQAP-PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
G + +++ P P P + L + + + +G I + YR G
Sbjct 279 GVSNFAQLIVREPPRPIAPPQLLGVGPTYLLIQLNANSI---IGDGPIILKEVEYRMTSG 335
Query 564 NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG----GKDGPEFTFTTP-------- 611
+ T + + Y L L DT Y +R+ T G G GP T
Sbjct 336 SWTETH-AVNAPTYKLWHLDPDTEYEIRVL-LTRPGEGGTGLPGPPLITRTKCAEPMRTP 393
Query 612 ---KFAQGEIEAIVV---PVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQ 665
K A+ + I V + V C++ + + SK+
Sbjct 394 KTLKIAEIQARRIAVDWESLGYNITRCHTFNVTICYH---------YFRGHNESKADCLD 444
Query 666 WSP--------HTPPRHNFNSKDQM--YSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFK 715
P H PP N + K + ++ ++++ + + P P F+
Sbjct 445 MDPKAPQHVVNHLPPYTNVSLKMILTNPEGRKESEETIIQTDEDVPGPVPVKSLQGTSFE 504
Query 716 KEKINT----EGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQV 771
+ + I SS S + T S + ST H + H
Sbjct 505 NKIFLNWKEPLDPNGIITQYEISYSSIRSFDPAVPVAGPPQTVSNLWNST--HHVFMHLH 562
Query 772 PSV--QVFSRSESTQ 784
P Q F R+ + +
Sbjct 563 PGTTYQFFIRASTVK 577
>sp|P22105|TENX_HUMAN Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB
PE=1 SV=5
Length=4244
Score = 105 bits (262), Expect = 1e-21, Method: Composition-based stats.
Identities = 74/487 (15%), Positives = 138/487 (28%), Gaps = 49/487 (10%)
Query 125 PPEKPK--NLSCIVNEGKKMRCEW--DGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
PP KP+ L+ + W G+ H + ++ K D T
Sbjct 3057 PPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEDGVT 3114
Query 181 SCTVDYSTVYFVN-IEVW----VEAENALGKVTSDHINFDPVYKVKPNPPHNL---SVIN 232
++ Y +N V +A+G + + P P +
Sbjct 3115 ISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTV 3174
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
+ L L+WT P + +QY+ +D S TV L+P
Sbjct 3175 TGSSPDSLSLSWTVPQ---GRFDSFTVQYKDRDGQP----QVVRVRGEESEVTVGGLEPG 3227
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
+Y + +G P ++ + +V L W
Sbjct 3228 RKYKMHL---YGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSD-SVGLSW- 3282
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNYTVNA--TKLTVNLTNDRYLATLTVR---NLVG 407
A G + V + Q V+ + V+ + + N
Sbjct 3283 ----TVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKR 3338
Query 408 KSDAAVLTIPACDFQATHPVMDLKAF-PKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
V A D + + + +L + + + WT P +++++ +
Sbjct 3339 HGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQV 3398
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD---GPGSPESIKAYLKQAPPSKGP 523
+ R L S+ Y + + GP S +S A L++ P
Sbjct 3399 VP-----VAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLG 3453
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLT 583
+ + + L W G ++ + YR G AV V + T+ L
Sbjct 3454 ELTVAEETSSSLRLSWTV-----AQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLE 3508
Query 584 SDTLYMV 590
Y
Sbjct 3509 PGKKYKF 3515
Score = 103 bits (256), Expect = 7e-21, Method: Composition-based stats.
Identities = 75/459 (16%), Positives = 134/459 (29%), Gaps = 69/459 (15%)
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
V V A T P P + + L L+WT P
Sbjct 2493 TVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQ---GRF 2549
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC-MKEDGKGYWSDW 313
+ +QY+ +D + S TV+ L+P +Y + + G S
Sbjct 2550 DSFTVQYKDRDGRPQA----VRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAV 2605
Query 314 -SEEASGITYEDRPS--KAPSFWYKIDPSHTQGYR--TVQLVWKTLPPFEANGKILDYEV 368
E T + P+ P ++ ++ L W G+ + V
Sbjct 2606 GVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSW-----TVPEGQFDHFLV 2660
Query 369 TLTRWKSHLQNYTVNATK--LTVNLTNDRYLATLTVRNLVGK---SDAAVLTIPACDFQA 423
+ V + +T++ + + + G +V+ + A + +
Sbjct 2661 QYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEET 2720
Query 424 THPVMDLKAF----------------PKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
P + L + WT P+ + +++ D P +
Sbjct 2721 PSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDR-DGRPQV 2779
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLI---------TVTPVYADGPGSPESIKAYLKQAP 518
+ E+ V G L + Y + V PV G +PE +A QA
Sbjct 2780 MRVRGEESEVT----VGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPE-DEAETTQAV 2834
Query 519 P---SKGPT------VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
P + P + + L W V G ++ + YR G V
Sbjct 2835 PTTTPEPPNKPRLGELTVTDATPDSLSLSW-----MVPEGQFDHFLVQYRNGDGQPKVVR 2889
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
V T+S L D Y + + + G + GP
Sbjct 2890 VPGHEDGVTISGLEPDHKYKMNLYGF-HGGQRVGPISVI 2927
Score = 103 bits (255), Expect = 9e-21, Method: Composition-based stats.
Identities = 71/394 (18%), Positives = 125/394 (32%), Gaps = 38/394 (10%)
Query 225 PHNLSVINSEELSSILKLTWT-NPSIKSVIILKYNIQYRTKDASTWSQIPPED-----TA 278
P + ++ +S L+L W P +L++ + ++ P
Sbjct 3656 PRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV---PSPSTLEPHPRPLLQRELMVP 3712
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
TR S ++DL+ T Y + ++ K S + + T S +
Sbjct 3713 GTRHSAVLRDLRSGTLYSLTLYGLRGPHKAD----SIQGTARTL----SPVLESPRDL-Q 3763
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ-NYTVNATKLTVNLTNDRYL 397
+ ++ W PP A+ + Y++ +Q + KL + RY
Sbjct 3764 FSEIRETSAKVNWMP-PPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYE 3822
Query 398 ATLTVRNLVGKSDA-AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
T+ +S+ D ++L + + W P+ V Y ++
Sbjct 3823 VTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLT----EGFAVLHWKPPQNPVDTYDVQ 3878
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
AP Q E Y +L Y TV + SP SI
Sbjct 3879 -----VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGL 3933
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
P + K+V A+L W + PV Y + + T G + + T
Sbjct 3934 EAPR---DLEAKEVTPRTALLTWTEPPVRPA-----GYLLSFHTPGGQNQEILLPGGITS 3985
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ L L T Y R+ A + +FTT
Sbjct 3986 HQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 4019
Score = 102 bits (254), Expect = 1e-20, Method: Composition-based stats.
Identities = 106/708 (15%), Positives = 184/708 (26%), Gaps = 117/708 (17%)
Query 122 SGLPPEKP---KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDT 178
S P P NL + W E +T F ++ + +
Sbjct 1152 SDPSPGTPPHLGNLWVTDPTPDSLHLSW-TVPEGQFDT-FMVQYRDRDGRPQVVPVE--G 1207
Query 179 PTSCTVDYSTVYFVNIEVWVE-AEN--ALGKVTSDHINFDPVYKVKPNP-----PHNLSV 230
P V S + N G +T+D + P P P +
Sbjct 1208 PERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGEL 1267
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ L+L+WT + +QY+ + A + TV L
Sbjct 1268 TVTGVTPDSLRLSWTV---AQGPFDSFMVQYKDAQGQPQA----VPVAGDENEVTVPGLD 1320
Query 291 PFTEYVF--------------RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
P +Y + + S G + P
Sbjct 1321 PDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGT---EAPESPEEPLLGE 1377
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA--TKLTVNLTND 394
++ L W G + V + V +++TV
Sbjct 1378 LTVTGSSPDSLSLFW-----TVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEP 1432
Query 395 RYLA-----------TLTVRNLVG-KSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWV 441
+ + + VG + T PA + + +L N + +
Sbjct 1433 GHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGL 1492
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
WT P +I+++ D P + + V NL + Y + + ++
Sbjct 1493 SWTVPEGQFDSFIVQYK-DKDGQPQVVPVAADQREVTVY----NLEPERKYKMNMYGLHD 1547
Query 502 DGPGSPESIKAYLKQAPP------SKGP------TVRTKKVGKNEAVLEWDQLPVDVQNG 549
P S+ PP SK P + + + L W G
Sbjct 1548 GQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVP-----EG 1602
Query 550 FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF--- 606
++ + Y+ G V V + E T+ L Y + G +DG
Sbjct 1603 EFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLF-----GIQDGKRRSPV 1657
Query 607 TFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQW 666
+ A+G+ + P L L W P P S W
Sbjct 1658 SVEAKTVARGD-ASPGAPPRLGEL---------------------WVTDPTP-DSLRLSW 1694
Query 667 SPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSS 726
T P F+S + D + V VE P D F + +
Sbjct 1695 ---TVPEGQFDSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHG 1751
Query 727 GIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHS--GYRHQVP 772
+ + + + +Q +TV + G VP
Sbjct 1752 PLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVP 1799
Score = 93.0 bits (229), Expect = 1e-17, Method: Composition-based stats.
Identities = 55/401 (14%), Positives = 106/401 (26%), Gaps = 48/401 (12%)
Query 213 NFDPVYKVKPNPPHNLSV---INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW 269
V + P PP + ++ L L+W P + +QYR D
Sbjct 3046 TTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPE---GQFDHFLVQYRNGDGQP- 3101
Query 270 SQIPPEDTASTRSSFTVQDLKPFTEYVF---------RIRCMKEDGKGYWSDWSEEASGI 320
T+ L+P +Y R+ + G S
Sbjct 3102 ---KAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPST 3158
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY 380
+ P + + S ++ L W G+ + V Q
Sbjct 3159 EAPEAPEEPLLGELTVTGSS---PDSLSLSW-----TVPQGRFDSFTVQYKDRDGQPQVV 3210
Query 381 TVNA--TKLTVNLTNDR-----YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF 433
V +++TV +L L VG +T P P + A
Sbjct 3211 RVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAV 3270
Query 434 P--KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
+ + + WT + +++++ + + R L ++
Sbjct 3271 AAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVP-----VSGDLRAVAVSGLDPARK 3325
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGP--TVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y + + P ++A + + L W G
Sbjct 3326 YKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVP-----EG 3380
Query 550 FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMV 590
++ + Y+ G V V ++ E T+ L Y
Sbjct 3381 EFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRF 3421
Score = 88.8 bits (218), Expect = 2e-16, Method: Composition-based stats.
Identities = 59/423 (14%), Positives = 112/423 (26%), Gaps = 70/423 (17%)
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
+ L L+WT P + +QY+ +D S TV L+P
Sbjct 2420 TGSSPDSLSLSWTVPQ---GRFDSFTVQYKDRDGRP----QVVRVGGEESEVTVGGLEPG 2472
Query 293 TEYVF---------RIRCMKEDGKGYWSDWSEEASGITY--EDRPSKAPSFWYKIDPSHT 341
+Y R+ + G + +E T + P
Sbjct 2473 RKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTG 2532
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA--TKLTVNLTNDRYLA- 398
++ L W G+ + V Q V +K+TV
Sbjct 2533 SSPDSLSLSW-----TVPQGRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYK 2587
Query 399 -------------TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF---PKDNMLWVE 442
++ + +P + + + L +
Sbjct 2588 MHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLS 2647
Query 443 WTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD 502
WT P +++++ D P + G + G L Y + + +
Sbjct 2648 WTVPEGQFDHFLVQYRN-GDGQPKAV---RVPGHEDGVTISG-LEPDHKYKMNLYGFHGG 2702
Query 503 GPGSPESIKAYL--KQAPPSK---------------GPTVRTKKVGKNEAVLEWDQLPVD 545
P S+ ++ PS + + L W
Sbjct 2703 QRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSW-----T 2757
Query 546 VQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ G ++T+ Y+ G + V +E T+ L Y + + EG + GP
Sbjct 2758 IPQGHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGL-HEGRRVGPV 2816
Query 606 FTF 608
T
Sbjct 2817 STV 2819
Score = 88.0 bits (216), Expect = 3e-16, Method: Composition-based stats.
Identities = 76/491 (15%), Positives = 143/491 (29%), Gaps = 58/491 (12%)
Query 126 PEKP--KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
PE+P L+ + + W +FT++ + + + + +
Sbjct 3164 PEEPLLGELTVTGSSPDSLSLSWT--VPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTV 3221
Query 184 VDYSTVYFVNIEVW-VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
+ ++ + +G V++ I P+ P P + + S + L
Sbjct 3222 GGLEPGRKYKMHLYGLHEGQRVGPVSTVGITA-PLPTPLPVEPRLGELAVAAVTSDSVGL 3280
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
+WT + +QYR + + + V L P +Y F +
Sbjct 3281 SWTV---AQGPFDSFLVQYRDAQGQPQA----VPVSGDLRAVAVSGLDPARKYKF-LLFG 3332
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
++GK + E + P PS +V L W G+
Sbjct 3333 LQNGKRHGPVPVEART------APDTKPSPRLGELTVTDATPDSVGLSW-----TVPEGE 3381
Query 363 ILDYEVTLTRWKSHLQNYTV--NATKLTVNLTNDRYLAT-----LTVRNLVGKSDAAVLT 415
+ V LQ V N ++TV L+ R +G A T
Sbjct 3382 FDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTT 3441
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
P H A + L + WT + +++++ +D P +
Sbjct 3442 APLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYR-DTDGQPRAVPVAAD-- 3498
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL--KQAPPSKGPT--------- 524
RT +L K Y + + P S ++ P+
Sbjct 3499 --QRTVTVEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEE 3556
Query 525 -----VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTL 579
+ + L W V G ++ + Y G A+ VD ++ +
Sbjct 3557 PRLGVLTVTDTTPDSMRLSW-----SVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILI 3611
Query 580 SSLTSDTLYMV 590
S L T Y
Sbjct 3612 SGLEPSTPYRF 3622
Score = 88.0 bits (216), Expect = 3e-16, Method: Composition-based stats.
Identities = 61/429 (14%), Positives = 118/429 (28%), Gaps = 66/429 (15%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + ++ L L+WT P + +QY+ D
Sbjct 2304 PRLEELTVTDATPDSLSLSWTVPE---GQFDHFLVQYKNGDGQP----KATRVPGHEDRV 2356
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS----- 339
T+ L+P +Y + G S E+ PS +P
Sbjct 2357 TISGLEPDNKYKMNL--YGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLL 2414
Query 340 -----HTQGYRTVQLVWKTLPPFEANGKILDYE--------VTLTRWKSHLQNYT-VNAT 385
++ L W T+P + + Y+ V + +S +
Sbjct 2415 GELTVTGSSPDSLSLSW-TVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGR 2473
Query 386 KLTVNLTNDRYLATLTVRNLVG---------KSDAAVLTIPACDFQATHPVMDLKAFPKD 436
K ++L + + VG ++ + P++
Sbjct 2474 KYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGS 2533
Query 437 N--MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
+ L + WT P+ + +++ + + G L + Y +
Sbjct 2534 SPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQAV-----RVGGQESKVTVRGLEPGRKYKM 2588
Query 495 TVTPVYADGPGSPESIKAYLK------QAPPSKGPT---------VRTKKVGKNEAVLEW 539
+ ++ P S + QA P+ P + + L W
Sbjct 2589 HLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSW 2648
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
G ++ + YR G AV V T+S L D Y + + + G
Sbjct 2649 TVP-----EGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGF-HGG 2702
Query 600 GKDGPEFTF 608
+ GP
Sbjct 2703 QRVGPISVI 2711
Score = 87.6 bits (215), Expect = 4e-16, Method: Composition-based stats.
Identities = 63/425 (15%), Positives = 116/425 (27%), Gaps = 67/425 (16%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + ++ L L+WT P + +QYR D
Sbjct 1988 PRLGELTVTDATPDSLSLSWTVPE---GQFDHFLVQYRNGDGQP----KAVRVPGHEEGV 2040
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT--- 341
T+ L+P +Y + G S E+ PS +P+
Sbjct 2041 TISGLEPDHKYKMNL--YGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLL 2098
Query 342 -------QGYRTVQLVWKTLPPFEANGKILDYEVTL--TRWKSHLQNYTVNATKLTVNLT 392
++ L W G+ + V + + +++TV
Sbjct 2099 GELTVTGSSPDSLSLSW-----TVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGL 2153
Query 393 NDR-----YLATLTVRNLVGKSDAAVLTIPACDFQATH------PVMDLKAFPKDNMLWV 441
+L L VG A +T P + M ++ D+ L +
Sbjct 2154 EPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDS-LSL 2212
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
WT P +++++ D P + G + G L Y + + +
Sbjct 2213 SWTVPEGQFDHFLVQFKN-GDGQPKAV---RVPGHEDGVTISG-LEPDHKYKMNLYGFHG 2267
Query 502 DGPGSPESIKAYL-----KQAPPSKG-------------PTVRTKKVGKNEAVLEWDQLP 543
P S ++ P+ + + L W
Sbjct 2268 GQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVP- 2326
Query 544 VDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
G ++ + Y+ G A V T+S L D Y + + + G + G
Sbjct 2327 ----EGQFDHFLVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGF-HGGQRVG 2381
Query 604 PEFTF 608
P
Sbjct 2382 PVSAI 2386
Score = 87.6 bits (215), Expect = 5e-16, Method: Composition-based stats.
Identities = 71/448 (16%), Positives = 126/448 (28%), Gaps = 68/448 (15%)
Query 203 ALGKVTSDHINFDPV---YKVKPN----PPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
G SD I + + + KP PP + ++ S L L WT P
Sbjct 1034 PPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPE---GEFD 1090
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+ IQY+ +D + S + L P +Y F + GK
Sbjct 1091 SFVIQYKDRDGQP----QVVPVEGPQRSAVITSLDPGRKYKFVL--YGFVGKKRHGPLVA 1144
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
EA + D P + + ++ L W G+ + V
Sbjct 1145 EAKILPQSDPSPGTPPHLGNLWVTD-PTPDSLHLSW-----TVPEGQFDTFMVQYRDRDG 1198
Query 376 HLQNYTVNAT--KLTVNLTNDRYLATLT---VRNLVGKSDAAVLTIPACDFQATHPVMDL 430
Q V V+ + + T + N A + + P +
Sbjct 1199 RPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEF 1258
Query 431 KAFP----------KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
P + L + WT + +++++ + P ++ V
Sbjct 1259 LEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYK-DAQGQPQAVPVAGDENEVTVP 1317
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYL------KQAP---------PSKGP-- 523
L + Y + + + PES+ A + P P
Sbjct 1318 ----GLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEP 1373
Query 524 ---TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLS 580
+ + L W G ++T+ Y+ G AV V +E T+
Sbjct 1374 LLGELTVTGSSPDSLSLFWTVP-----QGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVG 1428
Query 581 SLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
L Y + + EG + GP
Sbjct 1429 GLEPGHKYKMHLYGL-HEGQRVGPVSAV 1455
Score = 87.2 bits (214), Expect = 6e-16, Method: Composition-based stats.
Identities = 58/417 (14%), Positives = 116/417 (28%), Gaps = 55/417 (13%)
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
+ L L+WT P + +QY+ +D S TV L+P
Sbjct 2961 TGSSPDSLSLSWTIPQ---GRFDSFTVQYKDRDGRP----QVVRVRGEESEVTVGGLEPG 3013
Query 293 TEYVFRIRC-MKEDGKGYWSDW---SEEASGITYEDRP--SKAPSFWYKIDPSHTQGYR- 345
+Y + + G S + + T + P + P ++
Sbjct 3014 CKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATP 3073
Query 346 -TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK--LTVNLTNDRYLA---- 398
++ L W G+ + V + V + +T++ +
Sbjct 3074 DSLSLSWM-----VPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNL 3128
Query 399 -------TLTVRNLVG----KSDAAVLTIPACDFQATHPVMDLKAFPKDN--MLWVEWTT 445
+ + +G ++ + P++ + L + WT
Sbjct 3129 YGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTV 3188
Query 446 PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
P+ + +++ D P + + E+ V G L + Y + + ++
Sbjct 3189 PQGRFDSFTVQYKDR-DGQPQVVRVRGEESEVT----VGGLEPGRKYKMHLYGLHEGQRV 3243
Query 506 SPESIKAYLKQAP---PSKGP--TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
P S P P + + V + L W G ++ + YR
Sbjct 3244 GPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTV-----AQGPFDSFLVQYRD 3298
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA-YTDEGGKDGPEFTFTTPKFAQG 616
G AV V +S L Y + + P T P
Sbjct 3299 AQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPS 3355
Score = 84.9 bits (208), Expect = 3e-15, Method: Composition-based stats.
Identities = 75/457 (16%), Positives = 147/457 (32%), Gaps = 73/457 (16%)
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS 270
+ KP+ P + ++ + L+WT P + +QY+ KD
Sbjct 3343 PVEARTAPDTKPS-PRLGELTVTDATPDSVGLSWTVPE---GEFDSFVVQYKDKDG---- 3394
Query 271 QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
++ A+ + TVQ L+P +Y F + G+ S +++ E P
Sbjct 3395 RLQVVPVAANQREVTVQGLEPSRKYRFLL--YGLSGRKRLGPISADSTTAPLEKE---LP 3449
Query 331 SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN 390
++ + +++L W A G + V + V A + TV
Sbjct 3450 PHLGELTVAEETSS-SLRLSW-----TVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVT 3503
Query 391 L----TNDRYL---ATLTVRNLVGKSDAAVLTIPACDFQATH--------------PVMD 429
+ +Y L +G A +T P D A V+
Sbjct 3504 VEDLEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLT 3563
Query 430 LKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
+ D+M + W+ + +++++ + + + DG + + G L S
Sbjct 3564 VTDTTPDSMR-LSWSVAQGPFDSFVVQYEDTNGQPQALL----VDGDQSKILISG-LEPS 3617
Query 490 KCYLITVT---------PVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
Y + P+ A+G +++ P + V + L W+
Sbjct 3618 TPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPR-LSQLSVTDVTTSSLRLNWE 3676
Query 541 QLPVDVQNGFIRNYTI--------FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
P + F+ + + R ++ E + V + L L S TLY + +
Sbjct 3677 APPGAF-DSFLLRFGVPSPSTLEPHPRPLLQRE--LMVPGTRHSAVLRDLRSGTLYSLTL 3733
Query 593 AAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAF 629
G GP + A+ + P L F
Sbjct 3734 Y------GLRGPHKADSIQGTARTLSPVLESPRDLQF 3764
Score = 79.9 bits (195), Expect = 1e-13, Method: Composition-based stats.
Identities = 96/615 (16%), Positives = 160/615 (26%), Gaps = 113/615 (18%)
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ ++ WT + Y IQ+ S S+ S++ + L P EY
Sbjct 763 TTVRTEWTP---APGPVDAYEIQFIPTTEGA-SPPFTARVPSSASAYDQRGLAPGQEYQV 818
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
+R ++ G + T D P + + T T++L W
Sbjct 819 TVRALRGTSWGLP----ASKTITTMID----GPQDLRVVAVTPT----TLELGW-----L 861
Query 358 EANGKILDYEVTLTRWKSHLQNYTVN----ATKLTVNLTNDRYLATLTV----------- 402
++ + V+ + V T LT + Y+ T+T
Sbjct 862 RPQAEVDRFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPAS 921
Query 403 -RNLVGKSDAAVLTIPACDFQATHPVMD------------------LKAFPKDNMLWVEW 443
R G S +L + + + L V W
Sbjct 922 VRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVW 981
Query 444 TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADG 503
T ++ + L + + P ++ R L Y +++ V G
Sbjct 982 TAQPDTFAYFQL--RMRVPEGPGAH--EEVLPGDVRQALVPPPPPGTPYELSLHGVPPGG 1037
Query 504 PGSPESIK---AYLKQAPP---SKGP---TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
S I + P S P + + +L W G ++
Sbjct 1038 KPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVP-----EGEFDSF 1092
Query 555 TIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA--------------AYTDEGG 600
I Y+ G V V+ ++SL Y + A
Sbjct 1093 VIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQS 1152
Query 601 KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCF--NKRDLIKKHIWPNVPDP 658
P TP P L T G F RD + V P
Sbjct 1153 DPSPG----TPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGP 1208
Query 659 SKS-HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKE 717
+S ++ P R G T E ++ P PE L+
Sbjct 1209 ERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQ------- 1261
Query 718 KINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVF 777
+G + + S+ S S VQY V
Sbjct 1262 --------PLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAG---- 1309
Query 778 SRSESTQPLLDSEER 792
+E T P LD + +
Sbjct 1310 DENEVTVPGLDPDRK 1324
Score = 70.7 bits (171), Expect = 6e-11, Method: Composition-based stats.
Identities = 54/415 (13%), Positives = 114/415 (27%), Gaps = 58/415 (14%)
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
+ E S L L+W + IQY +D Q+ R+ T+
Sbjct 1886 ELTVEEATSHTLHLSWMV---TEGEFDSFEIQYTDRDG----QLQMVRIGGDRNDITLSG 1938
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS------HTQ 342
L+ Y+ + + + + I P
Sbjct 1939 LESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDA 1998
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK--LTVNLTNDRYLATL 400
++ L W G+ + V + V + +T++ + +
Sbjct 1999 TPDSLSLSW-----TVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKM 2053
Query 401 TVRNLVGK---SDAAVLTIPACDFQATHPVMDLKAFP----------------KDNMLWV 441
+ G +V+ + A + + P P + L +
Sbjct 2054 NLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSL 2113
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY- 500
WT P+ + +++ D P + G G L + Y + + ++
Sbjct 2114 SWTVPQGRFDSFTVQYKDR-DGRPQVV----RVGGEESEVTVGGLEPGRKYKMHLYGLHE 2168
Query 501 ADGPGSPESIKAYLKQAPPSKGP-------TVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
G ++ + P + + + + L W G +
Sbjct 2169 GRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVP-----EGQFDH 2223
Query 554 YTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
+ + ++ G AV V T+S L D Y + + + G + GP
Sbjct 2224 FLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGF-HGGQRVGPVSAV 2277
Score = 68.7 bits (166), Expect = 3e-10, Method: Composition-based stats.
Identities = 47/297 (16%), Positives = 86/297 (29%), Gaps = 37/297 (12%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P +L SE + K+ W P ++ + + Y+ D + + A T+
Sbjct 3757 ESPRDLQ--FSEIRETSAKVNWMPPPSRAD---SFKVSYQLADGGEPQSVQVDGQARTQ- 3810
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
+Q L P Y + ++ + SE +G P P+ ++ +
Sbjct 3811 --KLQGLIPGARYEVTVVSVRGF------EESEPLTGF-LTTVPD-GPTQLRALNLTEGF 3860
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL----TNDRYLA 398
L WK + Y+V +T + + + L + Y A
Sbjct 3861 A----VLHWKP-----PQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTA 3911
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWC 458
T+ + A +T P + WT P Y+L +
Sbjct 3912 TVRGLRGPNLTSPASITFTT---GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFH 3968
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
+ I G + L G L S Y + ++ P S
Sbjct 3969 TPGGQNQEIL----LPGGITSHQLLG-LFPSTSYNARLQAMWGQSLLPPVSTSFTTG 4020
Score = 67.6 bits (163), Expect = 6e-10, Method: Composition-based stats.
Identities = 75/528 (14%), Positives = 140/528 (27%), Gaps = 75/528 (14%)
Query 121 ISGLPPEKPK--NLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDT 178
+ PP +P+ L+ + W +F ++ + + D
Sbjct 1570 EASKPPLEPRLGELTVTDITPDSVGLSWT--VPEGEFDSFVVQYKDRDGQPQVVPVAADQ 1627
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK----PNPPHNL-SVINS 233
D + + GK S ++ + + P P L + +
Sbjct 1628 REVTIPDLEPSR--KYKFLLFGI-QDGKRRS-PVSVEAKTVARGDASPGAPPRLGELWVT 1683
Query 234 EELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
+ L+L+WT P + +Q++ KD S TV L
Sbjct 1684 DPTPDSLRLSWTVPE---GQFDSFVVQFKDKDGP-----QVVPVEGHERSVTVTPLDAGR 1735
Query 294 EYVFRIRC---MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
+Y F + K G +E S + + T +V L
Sbjct 1736 KYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLS 1795
Query 351 WKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT--KLTVNLTNDRYLATLTVR---NL 405
W G+ + V Q V + +++V + + L + +
Sbjct 1796 W-----TVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHG 1850
Query 406 VGKSDAAVLTIPA-------------CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
+ + I A H + L + W
Sbjct 1851 KRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDS 1910
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
+ +++ + G + L G L YL+T+ P ++A
Sbjct 1911 FEIQY----TDRDGQLQMVRIGGDRNDITLSG-LESDHRYLVTLYGFSDGKHVGPVHVEA 1965
Query 513 YL----------------KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
P G + + L W G ++ +
Sbjct 1966 LTVPEEEKPSEPPTATPEPPIKPRLG-ELTVTDATPDSLSLSWTVP-----EGQFDHFLV 2019
Query 557 FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
YR G AV V T+S L D Y + + + G + GP
Sbjct 2020 QYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGF-HGGQRMGP 2066
Score = 66.8 bits (161), Expect = 1e-09, Method: Composition-based stats.
Identities = 26/160 (16%), Positives = 48/160 (30%), Gaps = 10/160 (6%)
Query 435 KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
++ + EWT V Y +++ ++ A + Y + LA + Y +
Sbjct 761 EETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPF--TARVPSSASAYDQRGLAPGQEYQV 818
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
TV + G P S +R V L W + +
Sbjct 819 TVRALRGTSWGLPASKTITT---MIDGPQDLRVVAVTPTTLELGW-----LRPQAEVDRF 870
Query 555 TIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
+ Y + + V L+ L Y+V + A
Sbjct 871 VVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTA 910
Score = 63.0 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 33/216 (15%), Positives = 66/216 (31%), Gaps = 28/216 (13%)
Query 434 PKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
+ L + WT P +++++ D P + G + G L Y
Sbjct 1998 ATPDSLSLSWTVPEGQFDHFLVQYRN-GDGQPKAV---RVPGHEEGVTISG-LEPDHKYK 2052
Query 494 ITVTPVYADGPGSPESIKAYL---KQAP-----------PSKGP---TVRTKKVGKNEAV 536
+ + + P S+ ++ P P++ P + +
Sbjct 2053 MNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLS 2112
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
L W G ++T+ Y+ G V V +E T+ L Y + +
Sbjct 2113 LSWTVP-----QGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGL- 2166
Query 597 DEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLT 632
EG + GP + +A + + L +
Sbjct 2167 HEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTV 2202
Score = 62.2 bits (149), Expect = 3e-08, Method: Composition-based stats.
Identities = 53/333 (16%), Positives = 95/333 (29%), Gaps = 33/333 (10%)
Query 72 FTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKN 131
+ + + + S+V + LT L ++ G E P++
Sbjct 3702 RPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRD 3761
Query 132 LSCIVNEGKKMRCEW--DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
L + W R + ++ L + D +
Sbjct 3762 LQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQ-----SVQVDGQARTQKLQGLI 3816
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
EV V + S+ + P+ P L +N E L W P
Sbjct 3817 PGARYEVTVVSVRGF--EESEPLTGFLTTV--PDGPTQLRALNLTE--GFAVLHWKPPQN 3870
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ Y++Q A +T + + + DL T Y +R ++ G
Sbjct 3871 P---VDTYDVQVTAPGAPPLQA----ETPGSAVDYPLHDLVLHTNYTATVRGLR--GPNL 3921
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
S S + T + P + RT L W T PP G +L +
Sbjct 3922 TSPAS--ITFTTGLEAPRDLE--------AKEVTPRTALLTW-TEPPVRPAGYLLSFHTP 3970
Query 370 LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTV 402
+ + L + + +L + Y A L
Sbjct 3971 GGQNQEILLPGGITSHQLLGLFPSTSYNARLQA 4003
Score = 37.5 bits (85), Expect = 0.80, Method: Composition-based stats.
Identities = 26/130 (20%), Positives = 38/130 (29%), Gaps = 15/130 (12%)
Query 505 GSPESIKAYLKQAPPSKGPTV---RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY--- 558
GS Y + + PT+ R + + EW P G + Y I +
Sbjct 732 GSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAP-----GPVDAYEIQFIPT 786
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY--TDEGGKDGPEFTFTTPKFAQG 616
V SS + Y L Y V + A T G T TT
Sbjct 787 TEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLP--ASKTITTMIDGPQ 844
Query 617 EIEAIVVPVC 626
++ + V
Sbjct 845 DLRVVAVTPT 854
>sp|Q00993|UFO_MOUSE Tyrosine-protein kinase receptor UFO OS=Mus
musculus OX=10090 GN=Axl PE=1 SV=2
Length=888
Score = 104 bits (259), Expect = 1e-21, Method: Composition-based stats.
Identities = 77/420 (18%), Positives = 128/420 (30%), Gaps = 53/420 (13%)
Query 53 KCMDYFHVNANYIVWKTNHFTIP-----KEQYTIINRTASS---VTFTDIASLNIQLTCN 104
+C +VW + + + Q + V+ I++L +
Sbjct 49 RCELQVQGEPPEVVWLRDGQILELADNTQTQVPLGEDWQDEWKVVSQLRISALQLSDAGE 108
Query 105 ILTFGQLEQNVY----GITIISGLP--PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNF 158
LE + G + GLP E+P++ + N + C+ G E
Sbjct 109 YQCMVHLEGRTFVSQPGFVGLEGLPYFLEEPEDKAVPANTPFNLSCQAQGPPEP------ 162
Query 159 TLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVY 218
+ W +S + EA NA G TS
Sbjct 163 -VTLLWLQDAVPLAPV--TGHSSQHSLQTPGLNKTSSFSCEAHNAKGVTTS----RTATI 215
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST--W--SQIPP 274
V P PH+L V++ + L++ WT + N+Q D W PP
Sbjct 216 TVLPQRPHHLHVVSR--QPTELEVAWTPGLSGIYPLTHCNLQAVLSDDGVGIWLGKSDPP 273
Query 275 ED-----TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
ED + ++ L P T Y RI C G S W+ T E P
Sbjct 274 EDPLTLQVSVPPHQLRLEKLLPHTPYHIRISCSSSQG---PSPWTHWLPVETTEGVPLGP 330
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT-KLT 388
P + S + V + W+ P G +L Y + + + T ++T
Sbjct 331 PE-----NVSAMRNGSQVLVRWQE-PRVPLQGTLLGYRLAYRGQDTPEVLMDIGLTREVT 384
Query 389 VNLTNDRY----LATLTVRNLVGKSDAAVLT-IPACDFQATHPVMDLKAFPKDNMLWVEW 443
+ L DR ++T G ++ + P+ L + P W
Sbjct 385 LELRGDRPVANLTVSVTAYTSAGDGPWSLPVPLEPWRPGQGQPLHHLVSEPPPRAFSWPW 444
Score = 75.3 bits (183), Expect = 2e-12, Method: Composition-based stats.
Identities = 42/255 (16%), Positives = 68/255 (27%), Gaps = 30/255 (12%)
Query 368 VTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
V L H +++ N + N G + + TI
Sbjct 172 VPLAPVTGHSSQHSLQTP-----GLNKTSSFSCEAHNAKGVTTSRTATITVL----PQRP 222
Query 428 MDLKAFPK-DNMLWVEWTTPRESVKKYILEWCVL-------------SDKAPCITDWQQE 473
L + L V WT Y L C L P +
Sbjct 223 HHLHVVSRQPTELEVAWTP--GLSGIYPLTHCNLQAVLSDDGVGIWLGKSDPPEDPLTLQ 280
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK-AYLKQAPPSKGPTVRTKKVGK 532
L Y I ++ + GP + P P +
Sbjct 281 VSVPPHQLRLEKLLPHTPYHIRISCSSSQGPSPWTHWLPVETTEGVPLGPPENVSAMRNG 340
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD-SSHTEYTLSSLTSDTLYMVR 591
++ ++ W + V +Q G + Y + YR E +++ + L V
Sbjct 341 SQVLVRWQEPRVPLQ-GTLLGYRLAYRGQDTPEVLMDIGLTREVTLELRGDRPVANLTVS 399
Query 592 MAAYTDEGGKDGPEF 606
+ AYT G DGP
Sbjct 400 VTAYTSAG--DGPWS 412
Score = 63.7 bits (153), Expect = 6e-09, Method: Composition-based stats.
Identities = 25/164 (15%), Positives = 50/164 (30%), Gaps = 2/164 (1%)
Query 379 NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDLKAFPKDN 437
+ + +L L + Y ++ + G S L + + P ++ A +
Sbjct 282 SVPPHQLRLEKLLPHTPYHIRISCSSSQGPSPWTHWLPVETTEGVPLGPPENVSAMRNGS 341
Query 438 MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
+ V W PR ++ +L + + T T ++VT
Sbjct 342 QVLVRWQEPRVPLQGTLLGYRLAYRGQDTPEVLMDIGLTREVTLELRGDRPVANLTVSVT 401
Query 498 PVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
+ G G P S+ L+ P +G + W
Sbjct 402 AYTSAGDG-PWSLPVPLEPWRPGQGQPLHHLVSEPPPRAFSWPW 444
>sp|Q12866|MERTK_HUMAN Tyrosine-protein kinase Mer OS=Homo sapiens
OX=9606 GN=MERTK PE=1 SV=2
Length=999
Score = 104 bits (260), Expect = 1e-21, Method: Composition-based stats.
Identities = 66/396 (17%), Positives = 133/396 (34%), Gaps = 44/396 (11%)
Query 36 PVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTI-----INRTASSVT 90
++ H C + + I W + + + I + + +
Sbjct 103 IILSEHKGVKFNCSISVPNIYQDTT----ISWWKDGKELLGAHHAITQFYPDDEVTAIIA 158
Query 91 FTDIASLNIQLTCNILT-FGQLEQNVYGITIIS---GLP--PEKPKNLSCIVNEGKKMRC 144
I S+ + + + + I GLP ++P++++ N + C
Sbjct 159 SFSITSVQRSDNGSYICKMKINNEEIVSDPIYIEVQGLPHFTKQPESMNVTRNTAFNLTC 218
Query 145 EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
+ G E + W + + +P+ TV T V EA N
Sbjct 219 QAVGPPEP-------VNIFWVQNSSRVNEQPEKSPSVLTVPGLTEMAV---FSCEAHNDK 268
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK 264
G S + + P+PP +S+ NS S + ++W +IQ +
Sbjct 269 GLTVSKGVQINIKAI--PSPPTEVSIRNSTAHS--ILISWVPGFDGYSPFRNCSIQVKEA 324
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
D + + +T++ + ++ L+ Y + CM E G WS S T E
Sbjct 325 DPLSNGSVMIFNTSALPHLYQIKQLQALANYSIGVSCMNEIG---WSAVSPWILASTTEG 381
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH------LQ 378
PS AP + + V + W P + +G+++ Y ++ W+S L+
Sbjct 382 APSVAP---LNVTVFLNESSDNVDIRWMKPPTKQQDGELVGYRISHV-WQSAGISKELLE 437
Query 379 NYTVNAT--KLTVNLTNDRYLATLTVRNLVGKSDAA 412
N + +++V + N + G +
Sbjct 438 EVGQNGSRARISVQVHNATCTVRIAAVTRGGVGPFS 473
Score = 70.3 bits (170), Expect = 7e-11, Method: Composition-based stats.
Identities = 48/326 (15%), Positives = 97/326 (30%), Gaps = 45/326 (14%)
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATK-LTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
+A G + + S + + LTV + + + N G + + + I
Sbjct 219 QAVGPPEPVNIFWVQNSSRVNEQPEKSPSVLTVPGLTEMAVFSCEAHNDKGLTVSKGVQI 278
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
+ + ++ + + + W + Y S C ++ D
Sbjct 279 NIKAIPSPPTEVSIRN-STAHSILISWVPGFD---GY-------SPFRNCSIQVKEADPL 327
Query 477 VHRTYLRGN------------LAESKCYLITVTPVYADGPGSPESIK-AYLKQAPPSKGP 523
+ + + N L Y I V+ + G + A + PS P
Sbjct 328 SNGSVMIFNTSALPHLYQIKQLQALANYSIGVSCMNEIGWSAVSPWILASTTEGAPSVAP 387
Query 524 -TVRT-KKVGKNEAVLEWDQLPVDVQNGFIRNYTIF--YRTII-GNETAVNVDSSHTEYT 578
V + + W + P Q+G + Y I +++ E V + +
Sbjct 388 LNVTVFLNESSDNVDIRWMKPPTKQQDGELVGYRISHVWQSAGISKELLEEVGQNGSRAR 447
Query 579 LSSLTSDTLYMVRMAAYTDEGGKD--GPEFTF------------TTPKFAQGEIEAIVVP 624
+S + VR+AA T G P F +TP + I+
Sbjct 448 ISVQVHNATCTVRIAAVTRGGVGPFSDPVKIFIPAHGWVDYAPSSTPAPGNADPVLIIF- 506
Query 625 VCLAFLLTTLLGVLFCFNKRDLIKKH 650
C + L + R +++
Sbjct 507 GCFCGFILIGLILYISLAIRKRVQET 532
Score = 66.8 bits (161), Expect = 7e-10, Method: Composition-based stats.
Identities = 45/281 (16%), Positives = 81/281 (29%), Gaps = 20/281 (7%)
Query 42 SNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQL 101
N T C I W N + ++ ++ S +T + +
Sbjct 206 MNVTRNTAFNLTCQAVGPPEPVNIFWVQNSSRVNEQ----PEKSPSVLTVPGLTEM-AVF 260
Query 102 TCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFT-- 159
+C L + G+ I P P +S + + W G + +
Sbjct 261 SCEAHNDKGLTVSK-GVQINIKAIPSPPTEVSIRNSTAHSILISWVPGFDGYSPFRNCSI 319
Query 160 -LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPV 217
+K + N + V N +G S I
Sbjct 320 QVKEADPLSNGSVMIFNTSALPHLYQIKQLQALANYSIGVSCMNEIGWSAVSPWILASTT 379
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPS--IKSVIILKYNIQYRTKDASTWSQIPPE 275
P N++V E S + + W P + ++ Y I + + A ++ E
Sbjct 380 EGAPSVAPLNVTV-FLNESSDNVDIRWMKPPTKQQDGELVGYRISHVWQSAGISKELLEE 438
Query 276 ---DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ + R S V + T RI + G G +SD
Sbjct 439 VGQNGSRARISVQVHN---ATC-TVRIAAVTRGGVGPFSDP 475
>sp|P24062|IGF1R_RAT Insulin-like growth factor 1 receptor OS=Rattus
norvegicus OX=10116 GN=Igf1r PE=2 SV=2
Length=1370
Score = 104 bits (260), Expect = 2e-21, Method: Composition-based stats.
Identities = 68/487 (14%), Positives = 151/487 (31%), Gaps = 88/487 (18%)
Query 228 LSVINSEELSSILKLTW---TNPSIKSVIILKYNIQYRTK--------------DASTWS 270
L ++ + + +TW P + ++ + + Y+ +++W+
Sbjct 494 LRFTSTTTWKNRIIITWHRYRPPDYRD--LISFTVYYKEAPFKNVTEYDGQDACGSNSWN 551
Query 271 QIPPEDTASTRSS--FTVQDLKPFTEYVFRIRCM------KEDGKGYWSDWSEEASGITY 322
+ + + + LKP+T+Y ++ + + +G SE T
Sbjct 552 MVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGA---KSEILYIRTN 608
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
PS S + + + W PP NG + Y V R +
Sbjct 609 ASVPSIPLDVL-----SASNSSSQLIVKWN--PPTLPNGNLSYYIVRWQRQPQDGYLFRH 661
Query 383 N-ATKLTVNLTNDR-YLATLTVRNLVGKSD------------AAVLTIPACDFQATHPVM 428
N +K + + + K++ + +
Sbjct 662 NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEYRK 721
Query 429 DLKAFPKDNMLWVEWTTPRESVKK-------------YILEWCVLSDKAPCITDW---QQ 472
+ F +++ R V + + + ++D T++ +
Sbjct 722 VFENFLHNSIFVPRPERRRRDVLQVANTTMSSRSRNTTVADTYNITDPEEFETEYPFFES 781
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYAD----GPGSPESIKAYL--KQAPPSKGPTVR 526
RT + NL Y I + + G + + A + V
Sbjct 782 RVDNKERTVI-SNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT 840
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY---TLSSLT 583
+ +N L+W + + NG I Y I Y + + ++ + +Y L+ L
Sbjct 841 WEPRPENSIFLKWPE--PENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLN 898
Query 584 SDTLYMVRMAAYTDEGGKDGPEF---TFTTP---KFAQGEIEAIVVPVCLAFLLTTLLGV 637
Y R+ A + G +G F P + I +PV + ++ L+ +
Sbjct 899 PG-NYTARIQATSLSG--NGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIM 955
Query 638 LFCFNKR 644
L+ F+++
Sbjct 956 LYVFHRK 962
Score = 53.7 bits (127), Expect = 9e-06, Method: Composition-based stats.
Identities = 30/175 (17%), Positives = 53/175 (30%), Gaps = 15/175 (9%)
Query 147 DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN---- 202
R T + + + R TV + F + + + N
Sbjct 753 SRSRNTTVADTYNITDPEEFETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAE 812
Query 203 ALGKVTSDHINFDPV----YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
LG S+ + + P P V + + L W P + +IL Y
Sbjct 813 KLGCSASNFVFARTMPAEGADDIPGP-----VTWEPRPENSIFLKWPEPENPNGLILMYE 867
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
I+Y ++ + ++ + L P Y RI+ G G W+D
Sbjct 868 IKYGSQVEDQRECVSRQE-YRKYGGAKLNRLNPG-NYTARIQATSLSGNGSWTDP 920
Score = 40.6 bits (93), Expect = 0.097, Method: Composition-based stats.
Identities = 17/77 (22%), Positives = 34/77 (44%), Gaps = 6/77 (8%)
Query 191 FVNIEVWVEAENALGKVTSDHIN-----FDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ V+V+A L V +DHI + P L V+++ SS L + W
Sbjct 575 WTQYAVYVKAVT-LTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWN 633
Query 246 NPSIKSVIILKYNIQYR 262
P++ + + Y ++++
Sbjct 634 PPTLPNGNLSYYIVRWQ 650
>sp|P16419|MYPC2_CHICK Myosin-binding protein C, fast-type OS=Gallus
gallus OX=9031 GN=MYBPC2 PE=1 SV=3
Length=1132
Score = 104 bits (260), Expect = 2e-21, Method: Composition-based stats.
Identities = 61/516 (12%), Positives = 149/516 (29%), Gaps = 33/516 (6%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTF--GQLEQ 113
A + WK + + + + ++ I S + +
Sbjct 559 PISGEPAPTVTWKRGDQLFTATEGRVHIDSQADLSSFVIESAERSDEGRYCITVTNPVGE 618
Query 114 NVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD-GGRETHLE-TNFTLKSEWATHKFAD 171
+ + + P+ P+++ W+ + + T + ++ +
Sbjct 619 DSATLHVRVVDVPDPPQSVRVTSVGEDWAVLSWEAPPFDGGMPITGYLMERKKKGSMRWM 678
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVI 231
P + + V E+ V A NA+G + + P ++ +
Sbjct 679 KLNFEVFPDTTYESTKMIEGVFYEMRVFAVNAIGVSQPSLNTQPFMPIAPTSEPTHVVLE 738
Query 232 NSEELSSILKLTWTNPSI-KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + ++ +K W P + + Y +++ + ++ W E R T + L
Sbjct 739 DVTDTTATIK--WRPPERIGAGGVDGYLVEWCREGSNEWVAANTELVE--RCGLTARGLP 794
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSFWYKIDPSHTQGYRTVQL 349
+FR+ + GK + ++ + +RP + P + + +
Sbjct 795 TGERLLFRVISVNMAGKSPPATMAQPVTIREIVERPKIRLPRHLRQTYIRRVGEQVNLVI 854
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK---------LTVNLTNDRYLATL 400
++ P +VT +R L T + Y +
Sbjct 855 PFQGKPRP---------QVTWSREGGALPAEVQTRTSDVDSVFFIRSAARPLSGNYEMRV 905
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
+ N+ D A L + + + + N L ++W P++ I + V
Sbjct 906 RIDNM---EDCATLRLRVVERPGPPQAVRVMEVWGSNAL-LQWEPPKDDGNAEISGYTVQ 961
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS 520
+ + + + L Y V G + +
Sbjct 962 KADTRTMEWFTVLEHSRPTRCTVSELVMGNEYRFRVYSENVCGTSQEPATSHNTARIA-K 1020
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
+G T++ + + L V + YT+
Sbjct 1021 EGLTLKMVPYKERDLRAAPQFLTPLVDRSVVAGYTV 1056
>sp|Q9TU69|GHR_CANLF Growth hormone receptor OS=Canis lupus familiaris
OX=9615 GN=GHR PE=2 SV=1
Length=638
Score = 103 bits (257), Expect = 2e-21, Method: Composition-based stats.
Identities = 47/217 (22%), Positives = 86/217 (40%), Gaps = 26/217 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA-------THKFADCKAK-RDT 178
EKPK C E + C W G L+ +++ + T ++ +C
Sbjct 49 EKPKFTKCRSPELETFSCHWTDGVRHGLKNAGSVQLFYIRRSTQEWTQEWKECPDYVSAG 108
Query 179 PTSCTVDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS----VINS 233
SC + S T ++ + + + T D F V+P+PP L+ I+
Sbjct 109 ENSCYFNSSYTSIWIPYCIKLTSNGG----TVDQKCFSVEEIVQPDPPIGLNWTLLNISL 164
Query 234 EELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
+ + +++ W P V I+LKY +QY+ + S W + P +S V L
Sbjct 165 TGIHADIQVRWEPPPNADVQKGWIVLKYELQYKEVNESQWKMMDPVSA----TSVPVYSL 220
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
+ EY R+R + + + + ++SE + P
Sbjct 221 RLDKEYEVRVRSRQRNSE-KYGEFSEALYVTLPQMSP 256
Score = 69.1 bits (167), Expect = 1e-10, Method: Composition-based stats.
Identities = 69/334 (21%), Positives = 114/334 (34%), Gaps = 50/334 (15%)
Query 447 RESVKKYILEW--CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
R S +++ EW C A + + T Y I +T
Sbjct 88 RRSTQEWTQEWKECPDYVSAGENSCYFNSSYTSIW----------IPYCIKLTSNGGTVD 137
Query 505 GSPESIKAYLKQAPPSKGPTVRTKKVGKN----EAVLEWDQLP-VDVQNG-FIRNYTIFY 558
S++ ++ PP + + + W+ P DVQ G + Y + Y
Sbjct 138 QKCFSVEEIVQPDPPIGL-NWTLLNISLTGIHADIQVRWEPPPNADVQKGWIVLKYELQY 196
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA--YTDEGGKDGPEFTFTT-PKFAQ 615
+ + ++ + S T + SL D Y VR+ + E + E + T P+ +
Sbjct 197 KEVNESQWKMMDPVSATSVPVYSLRLDKEYEVRVRSRQRNSEKYGEFSEALYVTLPQMSP 256
Query 616 GEIEA-IVVPVCLAFLL----TTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHT 670
E P L + T++ LF F+K+ IK I P VP P I P
Sbjct 257 FACEEDFQFPWFLIIIFGIFGLTMILFLFIFSKQQRIKMLILPPVPVP---KIKGIDPDL 313
Query 671 PPRHNF-----------NSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKI 719
N K + Y+D ++ + ++I+ D+K D L EK
Sbjct 314 LKEGKLEEVNTILAIHDNYKPEFYNDDSWVEFIELDIDDLDEKTEGSDTDRLLSNDHEK- 372
Query 720 NTEGHSSGIGG----SSCMSSSRPSISSSDENES 749
+ +G S S P I +D N S
Sbjct 373 ----SLNILGAKDDDSGRTSCYEPDILETDFNAS 402
Score = 39.8 bits (91), Expect = 0.14, Method: Composition-based stats.
Identities = 25/169 (15%), Positives = 50/169 (30%), Gaps = 14/169 (8%)
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVR--NLVGKSDAAVLTIPACDF 421
+ WK + N + ++ + G D ++
Sbjct 89 RSTQEWTQEWKECPDYVSAGENSCYFNSSYTSIWIPYCIKLTSNGGTVDQKCFSV-EEIV 147
Query 422 QATHPV------MDLKAFPKDNMLWVEWTTPRES--VKKYILEWCVLSDKAPCITDWQQE 473
Q P+ +++ + V W P + K +I+ L K + W+
Sbjct 148 QPDPPIGLNWTLLNISLTGIHADIQVRWEPPPNADVQKGWIVLKYELQYKEVNESQWKMM 207
Query 474 DGTVHRTYLRGNLAESKCYLITVTP--VYADGPGS-PESIKAYLKQAPP 519
D + +L K Y + V ++ G E++ L Q P
Sbjct 208 DPVSATSVPVYSLRLDKEYEVRVRSRQRNSEKYGEFSEALYVTLPQMSP 256
>sp|O14522|PTPRT_HUMAN Receptor-type tyrosine-protein phosphatase
T OS=Homo sapiens OX=9606 GN=PTPRT PE=1 SV=6
Length=1441
Score = 104 bits (259), Expect = 2e-21, Method: Composition-based stats.
Identities = 71/518 (14%), Positives = 152/518 (29%), Gaps = 76/518 (15%)
Query 95 ASLNIQLTCNILTFGQLEQNVYGITIISGLPP-EKP-----KNLSCIVNEGKKMRC---- 144
+ L V + +++ P + P +N+ V + +C
Sbjct 159 HFYQVIFESVSLKGHPGYIAVDEVRVLA-HPCRKAPHFLRLQNVEVNVGQNATFQCIAGG 217
Query 145 -----------EWDGGRETHLETNFTL--KSEWATHKFADCKAKRDTPTSCTVDYSTVYF 191
+W+ GR+T L + + AT AD + + C +
Sbjct 218 KWSQHDKLWLQQWN-GRDTALMVTRVVNHRRFSATVSVADTAQRSVSKYRCVIRSDG--- 273
Query 192 VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK- 250
G S+ + + K P P ++ W P+
Sbjct 274 -------------GSGVSN--YAELIVKEPPTPIAPPELLAVGATYL-----WIKPNANS 313
Query 251 ---SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
I+ ++YRT TW++ D ++ + L P EY R+ + G+
Sbjct 314 IIGDGPIILKEVEYRT-TTGTWAETHIVD----SPNYKLWHLDPDVEYEIRVL-LTRPGE 367
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT----LPPFEANGKI 363
G + T P P +D R + L W+ + +
Sbjct 368 GGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRA----RQLTLQWEPFGYAVTRCHSYNLT 423
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS---DAAVLTIPACD 420
+ Y+ + + + ++ T+ L + + ++ D
Sbjct 424 VQYQYVFNQQQYEAEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEED 483
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTV 477
P+ ++ P + ++++W P E+ + Y + + + P Q
Sbjct 484 VPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVF 543
Query 478 ----HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN 533
+L L Y T+ A G G P + + K + PS + +
Sbjct 544 KLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPEYDTDTPLNET 603
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD 571
+ + P + + Y + + ++ D
Sbjct 604 DTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAAD 641
Score = 71.0 bits (172), Expect = 4e-11, Method: Composition-based stats.
Identities = 50/341 (15%), Positives = 96/341 (28%), Gaps = 34/341 (10%)
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE- 358
RC+ G S S A I E AP + ++ +W
Sbjct 266 RCVIRSDGG--SGVSNYAELIVKEPPTPIAPPELLAVGATY---------LWIKPNANSI 314
Query 359 -ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR---YLATLTVR---NLVGKSDA 411
+G I+ EV + + D Y + +
Sbjct 315 IGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPG 374
Query 412 AVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKK-YILEWCVLSDKAPCITD 469
LT H +++ + L ++W +V + + V
Sbjct 375 PPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQ 434
Query 470 WQQEDGTVHRT-YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTK 528
++ E+ + Y L + + +G E + ++ P P +
Sbjct 435 YEAEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESIQ 494
Query 529 K-VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS---------SHTEYT 578
+ + ++W P + NG I Y I Y+ + + + ++ S + T +
Sbjct 495 GGPFEEKIYIQWK--PPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHL 552
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE 619
L T Y + A T +G T A E
Sbjct 553 FVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPE 593
Score = 56.4 bits (134), Expect = 1e-06, Method: Composition-based stats.
Identities = 37/237 (16%), Positives = 67/237 (28%), Gaps = 17/237 (7%)
Query 397 LATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR----ESVKK 452
+R+ G + + + +L A LW++ +
Sbjct 264 KYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGA-TYLWIKPNANSIIGDGPIIL 322
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV---TPVYADGPGSPES 509
+E+ + W + Y +L Y I V P
Sbjct 323 KEVEYRTTTGT------WAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPP 376
Query 510 IKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV 568
+ K A P GP V + + L+W+ V N T+ Y+ + +
Sbjct 377 LTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQYE 436
Query 569 NVDSSHTE--YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
+ T YTL L +R+ EG + E T + G + +
Sbjct 437 AEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESI 493
>sp|Q4KMG0|CDON_HUMAN Cell adhesion molecule-related/down-regulated
by oncogenes OS=Homo sapiens OX=9606 GN=CDON PE=1 SV=2
Length=1287
Score = 104 bits (258), Expect = 3e-21, Method: Composition-based stats.
Identities = 64/377 (17%), Positives = 111/377 (29%), Gaps = 72/377 (19%)
Query 125 PPEKPKNLSC-IVNEGKKMRCEWDGGRETHLETN-FTLKSEWATH--------------- 167
P+ P LS + W G++ L N + +K
Sbjct 576 VPDAPIILSPPQTHTPDTYNLVWRAGKDGGLPINAYFVKYRKLDDGVGMLGSWHTVRVPG 635
Query 168 ----------------------------------KFADCKAKRDTPTSCTVDYSTVYFVN 193
F K K + + V
Sbjct 636 SENELHLAELEPSSLYEVLMVARSAAGEGQPAMLTFRTSKEKTASSKNTQASSPPVGIPK 695
Query 194 IEVWVEA-ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV 252
V EA N G V +D + P P ++ + E S + +TW +
Sbjct 696 YPVVSEAANNNFGVVLTDSSR----HSGVPEAPDRPTISTASETS--VYVTWIPRANGGS 749
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
I + ++Y+ S W + ED ++ S V+ L+P + Y FR+ + G+ + S
Sbjct 750 PITAFKVEYKRMRTSNW-LVAAEDIPPSKLSVEVRSLEPGSTYKFRVIAINHYGESFRSS 808
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR 372
S + + +R S P I + + L W +P N I + +
Sbjct 809 ASRPYQVVGFPNRFSSRPITGPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRP 868
Query 373 WKSHL----QNYTVNATK----LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
S + V +K + Y + N G+S+ + + I +
Sbjct 869 TDSDNDSDYKRDVVEGSKQWHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRV 928
Query 425 H-----PVMDLKAFPKD 436
PV DL P
Sbjct 929 PGASEYPVKDLSTPPNS 945
Score = 92.2 bits (227), Expect = 1e-17, Method: Composition-based stats.
Identities = 103/727 (14%), Positives = 200/727 (28%), Gaps = 172/727 (24%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTA---SSVT 90
+ +V L + C + A W N I + S VT
Sbjct 319 QDQIVSLGATVHFTCDVHGN-------PAPNCTWFHNAQPIHPSARHLTAGNGLKISGVT 371
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPP---EKPKNLSCIVNEGKKMRCEWD 147
D+ + N + F + I G P P + + + C
Sbjct 372 VEDVGMYQC-VADNGIGFMHSTGRLE-IENDGGFKPVIITAPVSAKVADGDFVTLSCNAS 429
Query 148 GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV 207
G + ++ D + S + +
Sbjct 430 GLPVPVI-------------RWYDSHGLITSHPSQVLRSKSRKSQL-------------S 463
Query 208 TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS 267
+ +N +PVY V +S L + I + ++ T A
Sbjct 464 RPEGLNLEPVYFVLSQA-----------GASSLHIQAVTQEHAGKYICEAANEHGTTQAE 512
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE-DGKGYWSDWSEEASGITYEDRP 326
+ P +T + + T+ D + R ++ G S + + E P
Sbjct 513 ASLMVVPFETNTKAETVTLPDAAQNDD-----RSKRDGSETGLLSSFPVKVHPSAVESAP 567
Query 327 SK------APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR-------- 372
K P + P T T LVW+ + I Y V +
Sbjct 568 EKNASGISVPDAPIILSPPQTHTPDTYNLVWRA--GKDGGLPINAYFVKYRKLDDGVGML 625
Query 373 --WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI--------PACDFQ 422
W + + N L + Y + R+ G+ A+LT + + Q
Sbjct 626 GSWHTVRVPGSENELHLAELEPSSLYEVLMVARSAAGEGQPAMLTFRTSKEKTASSKNTQ 685
Query 423 ATHPVMDLKAFP-----------------------------------KDNMLWVEWTT-- 445
A+ P + + +P + ++V W
Sbjct 686 ASSPPVGIPKYPVVSEAANNNFGVVLTDSSRHSGVPEAPDRPTISTASETSVYVTWIPRA 745
Query 446 -PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
+ + +E+ + + + + + +R L Y V + G
Sbjct 746 NGGSPITAFKVEYKRM-RTSNWLVAAEDIPPSKLSVEVRS-LEPGSTYKFRVIAINHYGE 803
Query 505 G------SPESIKAYLKQ--APPSKGPTVR-TKKVGKNEAVLEWDQLPVDVQNGFIRNYT 555
P + + + + P GP + T+ V + +L+W +P N I+ +
Sbjct 804 SFRSSASRPYQVVGFPNRFSSRPITGPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFY 863
Query 556 IFYRTIIGNETA----VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG------------ 599
I+YR + + V+ S + + L +T Y ++M + + G
Sbjct 864 IYYRPTDSDNDSDYKRDVVEGSKQWHMIGHLQPETSYDIKMQCFNEGGESEFSNVMICET 923
Query 600 -----------------------GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLG 636
G G T+P + + IV V +L ++
Sbjct 924 KVKRVPGASEYPVKDLSTPPNSLGSGGNVGPATSPARSSDMLYLIVGCVLGVMVLILMVF 983
Query 637 VLFCFNK 643
+ C K
Sbjct 984 IAMCLWK 990
>sp|Q90Z04|CDON_XENLA Cell adhesion molecule-related/down-regulated
by oncogenes OS=Xenopus laevis OX=8355 GN=cdon PE=2 SV=1
Length=1249
Score = 103 bits (257), Expect = 4e-21, Method: Composition-based stats.
Identities = 88/640 (14%), Positives = 179/640 (28%), Gaps = 92/640 (14%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT--F 91
E + SN C + I W N I I+ +T F
Sbjct 321 EDQSLTAGSNVRFSCESRGN-------PTPNITWFHNAVQIHASTRHQISGNKIRITSLF 373
Query 92 TDIASLNIQLTCNILTFGQLEQNVYGITIISGLPP--EKPKNLSCIVNEGKKMRC----- 144
+ + N Q+ Q + + P P ++ + + C
Sbjct 374 AQDSGIYQCFVNNEAGSAQVSQR-ATVHLKWSKPVIVSPPTSIRVANGDLVTLTCNATGI 432
Query 145 -----EW---DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV 196
W G +H KS A + + + S+ ++ +
Sbjct 433 PTPTIRWYDSHGPISSHPSQVLRSKSRKALLSKIGTPGQDPVHYTMSQAGSSSLYIR-AI 491
Query 197 WVE--------AENALGKVTSDHINFDPVYKVKPNP----PHNLSVINSEELSSILKLTW 244
V+ A N G +D Y++ P P +L+ + + S ++
Sbjct 492 TVQHAGTYKCEATNEFGSAHADAYLTVVPYEMSTKPEDITPLDLTQSDEGDYDSETRV-- 549
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK---------PFTEY 295
+ S + + + + ++ + P + + + +L P Y
Sbjct 550 PDHSQINEHKPEPRVTEKPYSGASLPEAPIILSPPQTTKPDMYNLMWRSGKDGGLPINAY 609
Query 296 VFRIRCMKEDGK--GYWS----DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
R R + +DG G W+ SE +T E PS + +G +
Sbjct 610 FVRYRKLDDDGNMVGNWNSIRVPASENEFPLT-ELEPSSLYEVLMVARNAAGEGQPAM-- 666
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
+T K + + + G
Sbjct 667 ------------------LTFRTSKERTSSSKNTQAPFPPIGVPKQTIIHGVSNTNNGLV 708
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITD 469
P + + + W+ + + +E+
Sbjct 709 PVDPSRHSGVPEAPDRPTISTASETSVYVTWIPRANGGSPITSFKVEYKRTGGH--WNAA 766
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADG------PGSPESIKAYLKQAP-PS-K 521
+ + + NL Y V + G P + Y + P P
Sbjct 767 AENIPPSKLSVEV-SNLEPGGLYKFRVIAINNYGESRRSTVSRPYQVAGYSIRLPNPLIV 825
Query 522 GPTV-RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA----VNVDSSHTE 576
GP + +T+ V + +L+W +P + N I+ + I+YR + + V+ +
Sbjct 826 GPRIDQTEAVTDTQILLKWTYIPENNNNTPIQGFYIYYRPTDSDNDSDYKRDMVEGTKLR 885
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
+ +S L +T Y ++M + + G D K +
Sbjct 886 HLISHLQPETSYDIKMQCFNERGASDYSNVMMCETKARRS 925
Score = 91.8 bits (226), Expect = 1e-17, Method: Composition-based stats.
Identities = 43/279 (15%), Positives = 89/279 (32%), Gaps = 17/279 (6%)
Query 168 KFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPV-YKVKPNPPH 226
F K + + + + + + + + + + DP + P P
Sbjct 668 TFRTSKERTSSSKNTQAPFPPIGVPKQTI----IHGVSNTNNGLVPVDPSRHSGVPEAPD 723
Query 227 NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 286
++ + E S + +TW + I + ++Y+ + W+ E+ ++ S V
Sbjct 724 RPTISTASETS--VYVTWIPRANGGSPITSFKVEYK-RTGGHWNA-AAENIPPSKLSVEV 779
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
+L+P Y FR+ + G+ S S Y R +ID +
Sbjct 780 SNLEPGGLYKFRVIAINNYGESRRSTVSRPYQVAGYSIRLPNPLIVGPRIDQTEAVTDTQ 839
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKSHL----QNYTVNATKL----TVNLTNDRYLA 398
+ L W +P N I + + S + V TKL + Y
Sbjct 840 ILLKWTYIPENNNNTPIQGFYIYYRPTDSDNDSDYKRDMVEGTKLRHLISHLQPETSYDI 899
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN 437
+ N G SD + + + + + +
Sbjct 900 KMQCFNERGASDYSNVMMCETKARRSPGASEYPVLDLST 938
>sp|Q99M80|PTPRT_MOUSE Receptor-type tyrosine-protein phosphatase
T OS=Mus musculus OX=10090 GN=Ptprt PE=1 SV=2
Length=1454
Score = 103 bits (257), Expect = 4e-21, Method: Composition-based stats.
Identities = 71/518 (14%), Positives = 152/518 (29%), Gaps = 76/518 (15%)
Query 95 ASLNIQLTCNILTFGQLEQNVYGITIISGLPP-EKP-----KNLSCIVNEGKKMRC---- 144
+ L V + +++ P + P +N+ V + +C
Sbjct 163 HFYQVIFESVSLKGHPGYIAVDEVRVLA-HPCRKAPHFLRLQNVEVNVGQNATFQCIAGG 221
Query 145 -----------EWDGGRETHLETNFTL--KSEWATHKFADCKAKRDTPTSCTVDYSTVYF 191
+W+ GR+T L + + AT AD + + C +
Sbjct 222 KWSQHDKLWLQQWN-GRDTALMVTRVVNHRRFSATVSVADTSQRSISKYRCVIRSDG--- 277
Query 192 VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK- 250
G S+ + + K P P ++ W P+
Sbjct 278 -------------GSGVSN--YAELIVKEPPTPIAPPELLAVGATYL-----WIKPNANS 317
Query 251 ---SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
I+ ++YRT TW++ D ++ + L P EY R+ + G+
Sbjct 318 IIGDGPIILKEVEYRT-TTGTWAETHIVD----SPNYKLWHLDPDVEYEIRVL-LTRPGE 371
Query 308 GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT----LPPFEANGKI 363
G + T P P +D R + L W+ + +
Sbjct 372 GGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRA----RQLTLQWEPFGYAVTRCHSYNLT 427
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS---DAAVLTIPACD 420
+ Y+ + + + ++ T+ L + + ++ D
Sbjct 428 VQYQYVFNQQQYEAEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEED 487
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTV 477
P+ ++ P + ++++W P E+ + Y + + + P Q
Sbjct 488 VPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVF 547
Query 478 ----HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN 533
+L L Y T+ A G G P + + K + PS + +
Sbjct 548 KLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPEYDADTPLNET 607
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD 571
+ + P + + Y + + ++ D
Sbjct 608 DTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAAD 645
Score = 71.0 bits (172), Expect = 5e-11, Method: Composition-based stats.
Identities = 50/341 (15%), Positives = 96/341 (28%), Gaps = 34/341 (10%)
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE- 358
RC+ G S S A I E AP + ++ +W
Sbjct 270 RCVIRSDGG--SGVSNYAELIVKEPPTPIAPPELLAVGATY---------LWIKPNANSI 318
Query 359 -ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR---YLATLTVR---NLVGKSDA 411
+G I+ EV + + D Y + +
Sbjct 319 IGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPG 378
Query 412 AVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKK-YILEWCVLSDKAPCITD 469
LT H +++ + L ++W +V + + V
Sbjct 379 PPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQ 438
Query 470 WQQEDGTVHRT-YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTK 528
++ E+ + Y L + + +G E + ++ P P +
Sbjct 439 YEAEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESIQ 498
Query 529 K-VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS---------SHTEYT 578
+ + ++W P + NG I Y I Y+ + + + ++ S + T +
Sbjct 499 GGPFEEKIYIQWK--PPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHL 556
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE 619
L T Y + A T +G T A E
Sbjct 557 FVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPE 597
Score = 56.0 bits (133), Expect = 2e-06, Method: Composition-based stats.
Identities = 37/237 (16%), Positives = 67/237 (28%), Gaps = 17/237 (7%)
Query 397 LATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR----ESVKK 452
+R+ G + + + +L A LW++ +
Sbjct 268 KYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGA-TYLWIKPNANSIIGDGPIIL 326
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV---TPVYADGPGSPES 509
+E+ + W + Y +L Y I V P
Sbjct 327 KEVEYRTTTGT------WAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPP 380
Query 510 IKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV 568
+ K A P GP V + + L+W+ V N T+ Y+ + +
Sbjct 381 LTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQYE 440
Query 569 NVDSSHTE--YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
+ T YTL L +R+ EG + E T + G + +
Sbjct 441 AEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESI 497
>sp|Q9BWV1|BOC_HUMAN Brother of CDO OS=Homo sapiens OX=9606 GN=BOC
PE=1 SV=1
Length=1114
Score = 103 bits (256), Expect = 4e-21, Method: Composition-based stats.
Identities = 57/363 (16%), Positives = 112/363 (31%), Gaps = 61/363 (17%)
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S + G + P++AP + T + +LVW+ IL Y V
Sbjct 456 GPASPQCPGEKGQGAPAEAP---IILSSPRTSKTDSYELVWRPRHEGSGRAPILYYVVKH 512
Query 371 TRWKSHLQNYTV-----NATKLTVNLT--NDRYLATLTVRNLVGKSDAAVLTIPA----- 418
+ + ++T+ N +LT+ Y + N G+ A++T
Sbjct 513 RKVTNSSDDWTISGIPANQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPK 572
Query 419 ------------CDFQATHPVMDLK-----------------AFPKDNMLWVEWTTPRE- 448
D P + + + ++V W
Sbjct 573 PEIMASKEQQIQRDDPGASPQSSSQPDHGRLSPPEAPDRPTISTASETSVYVTWIPRGNG 632
Query 449 --SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
++ + +E+ L I + + G L + Y V + G
Sbjct 633 GFPIQSFRVEYKKLKKVGDWILATSAIPPSRLSVEITG-LEKGTSYKFRVRALNMLGESE 691
Query 507 PES------IKAYLKQA--PPSKGPTVR-TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
P + + Y + P GP + T V + +L+W +P N I + I+
Sbjct 692 PSAPSRPYVVSGYSGRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIY 751
Query 558 YRTIIGNET----AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKF 613
YR + V+ +++S L +T Y ++M + + G + K
Sbjct 752 YRPTDSDNDSDYKKDMVEGDKYWHSISHLQPETSYDIKMQCFNEGGESEFSNVMICETKA 811
Query 614 AQG 616
+
Sbjct 812 RKS 814
Score = 90.7 bits (223), Expect = 3e-17, Method: Composition-based stats.
Identities = 57/352 (16%), Positives = 98/352 (28%), Gaps = 50/352 (14%)
Query 123 GLPPEKPKNLSC-IVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADCKAKR 176
G P E P LS ++ W GR L + +K T+ D
Sbjct 469 GAPAEAPIILSSPRTSKTDSYELVWRPRHEGSGRAPILY--YVVKHRKVTNSSDD-WTIS 525
Query 177 DTPTSCTVDYSTVYFVN--IEVWVEAENALGKVTSDHINFDPVYKVKPN----------- 223
P + T EV + A N G+ + + F + KP
Sbjct 526 GIPANQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIMASKEQQIQR 585
Query 224 -------------------PPHNL-SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT 263
PP S + + +TW I + ++Y+
Sbjct 586 DDPGASPQSSSQPDHGRLSPPEAPDRPTISTASETSVYVTWIPRGNGGFPIQSFRVEYKK 645
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+ +R S + L+ T Y FR+R + G+ S S Y
Sbjct 646 LKKVGDWILATSAIPPSRLSVEITGLEKGTSYKFRVRALNMLGESEPSAPSRPYVVSGYS 705
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN 383
R + P I + T+ L W +P N I + + S +
Sbjct 706 GRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDNDSDYKK 765
Query 384 A--------TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
++ Y + N G+S+ + + I + +
Sbjct 766 DMVEGDKYWHSISHLQPETSYDIKMQCFNEGGESEFSNVMICETKARKSSGQ 817
Score = 79.1 bits (193), Expect = 1e-13, Method: Composition-based stats.
Identities = 49/359 (14%), Positives = 100/359 (28%), Gaps = 66/359 (18%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSV--IILKYNIQYR--TKDASTWSQIPPED 276
P LS + +L W S IL Y +++R T + W+
Sbjct 471 PAEAPIILS-SPRTSKTDSYELVWRPRHEGSGRAPILYYVVKHRKVTNSSDDWT---ISG 526
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY--------------------------- 309
+ + T+ L P + Y + G+G
Sbjct 527 IPANQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIMASKEQQIQRD 586
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG--KILDYE 367
S ++S R S + T +V + W NG I +
Sbjct 587 DPGASPQSSSQPDHGRLSPPEAPDRPTI--STASETSVYVTWIP----RGNGGFPIQSFR 640
Query 368 VTLTRWKSH----LQNYTVNATKLTVNLT----NDRYLATLTVRNLVGKSDAAVLTIPAC 419
V + K L + ++L+V +T Y + N++G+S+ + + P
Sbjct 641 VEYKKLKKVGDWILATSAIPPSRLSVEITGLEKGTSYKFRVRALNMLGESEPSAPSRPYV 700
Query 420 ---------DFQATHPVMDLKAFPKDNMLWVEW-----TTPRESVKKYILEWCVLSDKAP 465
+ P + + + ++W + + + + +
Sbjct 701 VSGYSGRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDND 760
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPT 524
+G + + +L Y I + G ++ +A S G
Sbjct 761 SDYKKDMVEGDKYWHSI-SHLQPETSYDIKMQCFNEGGESEFSNVMICETKARKSSGQP 818
Score = 66.0 bits (159), Expect = 1e-09, Method: Composition-based stats.
Identities = 31/241 (13%), Positives = 60/241 (25%), Gaps = 44/241 (18%)
Query 404 NLVGKSDAAVLTIPACDFQATHPV-MDLKAFPKDNMLWVEWTTPRESVKKY-ILEWCVLS 461
VG + A P+ + K + + W E + IL + V
Sbjct 453 TSVGPASPQCPGEKGQGAPAEAPIILSSPRTSKTDSYELVWRPRHEGSGRAPILYYVVKH 512
Query 462 DKAPCITD-WQQED-GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ--- 516
K +D W L Y + + G G + +
Sbjct 513 RKVTNSSDDWTISGIPANQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPK 572
Query 517 -------------------------------APPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
+PP + + W +P
Sbjct 573 PEIMASKEQQIQRDDPGASPQSSSQPDHGRLSPPEAPDRPTISTASETSVYVTW--IPRG 630
Query 546 VQNGFIRNYTIFYRTI--IGNETAVN--VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
I+++ + Y+ + +G+ + S ++ L T Y R+ A G
Sbjct 631 NGGFPIQSFRVEYKKLKKVGDWILATSAIPPSRLSVEITGLEKGTSYKFRVRALNMLGES 690
Query 602 D 602
+
Sbjct 691 E 691
Score = 61.4 bits (147), Expect = 4e-08, Method: Composition-based stats.
Identities = 30/129 (23%), Positives = 48/129 (37%), Gaps = 6/129 (5%)
Query 497 TPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGK--NEAVLEWDQLPVDVQNGFIRNY 554
P + GP SP+ Q P++ P + + + L W I Y
Sbjct 450 RPPTSVGPASPQCP-GEKGQGAPAEAPIILSSPRTSKTDSYELVWRPRHEGSGRAPILYY 508
Query 555 TIFYRTIIGNETAVNV---DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP 611
+ +R + + + ++ TL+ L +LY V MAAY G TF T
Sbjct 509 VVKHRKVTNSSDDWTISGIPANQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTG 568
Query 612 KFAQGEIEA 620
+ + EI A
Sbjct 569 RRPKPEIMA 577
>sp|P23467|PTPRB_HUMAN Receptor-type tyrosine-protein phosphatase
beta OS=Homo sapiens OX=9606 GN=PTPRB PE=1 SV=3
Length=1997
Score = 103 bits (255), Expect = 8e-21, Method: Composition-based stats.
Identities = 62/383 (16%), Positives = 118/383 (31%), Gaps = 42/383 (11%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
V + P PP V + S+ L + WT S + Y +Q ++ +
Sbjct 103 TVVLQTDPLPPARFGVSKEKTTSTSLHVWWTP---SSGKVTSYEVQLFDENNQKIQGVQI 159
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
+++ S + +T +L ++Y I + GK +S ++ ++ PS
Sbjct 160 QESTS-WNEYTFFNLTAGSKYNIAITAV-SGGKRSFSVYTNGST------VPSPVKDIGI 211
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS--HLQNYTVNATKLTVNLT 392
+ ++ + W +G + Y + L H +AT +
Sbjct 212 ------STKANSLLISW-----SHGSGNVERYRLMLMDKGILVHGGVVDKHATSYAFHGL 260
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
YL LTV + + L V+W P +V
Sbjct 261 TPGYLYNLTVMTEA-AGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDS 319
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
Y + I + + + T+ + L + Y +TV+ V + + K
Sbjct 320 Y----NITLSHKGTIKESRVLAPWITETHFKE-LVPGRLYQVTVSCVSGE----LSAQKM 370
Query 513 YLKQAPPSKGPTVRTKKVGK-NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD 571
+ + P K + G+ V+ W G Y I + V
Sbjct 371 AVGRTFPDKVANLEANNNGRMRSLVVSWSPP-----AGDWEQYRILLFNDSVVLLNITVG 425
Query 572 SSHTEYTLS--SLTSDTLYMVRM 592
T+Y + L Y V +
Sbjct 426 KEETQYVMDDTGLVPGRQYEVEV 448
Score = 100 bits (249), Expect = 3e-20, Method: Composition-based stats.
Identities = 68/509 (13%), Positives = 152/509 (30%), Gaps = 55/509 (11%)
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISG-LPPEKPKNLSCIVNEGKKMRCEWDG--G 149
++ L N E+ + + + LPP + +S + W G
Sbjct 81 NLQDLQAGTIYNFRIISLDEERT--VVLQTDPLPPAR-FGVSKEKTTSTSLHVWWTPSSG 137
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS 209
+ T E + K + + T + ++ + + A + G S
Sbjct 138 KVTSYEVQL---FDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVS--GGKRS 192
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW 269
+ + P + I ++ L ++W++ S + +Y + K
Sbjct 193 FSVYTNGSTV-----PSPVKDIGISTKANSLLISWSHGS---GNVERYRLMLMDKGILVH 244
Query 270 SQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
+ +S+ L P Y + + G + W A
Sbjct 245 GGV----VDKHATSYAFHGLTPGYLYNLTVM-TEAAGLQNY-RW----------KLVRTA 288
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--RWKSHLQNYTVNATKL 387
P + ++ ++++ W+ P G + Y +TL+ + T+
Sbjct 289 PMEVSNLKVTNDGSLTSLKVKWQRPP-----GNVDSYNITLSHKGTIKESRVLAPWITET 343
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
L +TV + G+ A + + F ++ + L V W+ P
Sbjct 344 HFKELVPGRLYQVTVSCVSGELSAQKMAV-GRTFPDKVANLEANNNGRMRSLVVSWSPPA 402
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
++Y + +L + + + + L + Y + V G+
Sbjct 403 GDWEQYRI---LLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVES----GNL 455
Query 508 ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA 567
++ + + P +R K + + W Q PV Y I
Sbjct 456 KNSERCQGRTVPLAVLQLRVKHANETSLSIMW-QTPVAEWE----KYIISLADRDLLLIH 510
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
++ E+T + L YM + + +
Sbjct 511 KSLSKDAKEFTFTDLVPGRKYMATVTSIS 539
Score = 92.2 bits (227), Expect = 2e-17, Method: Composition-based stats.
Identities = 63/374 (17%), Positives = 116/374 (31%), Gaps = 51/374 (14%)
Query 227 NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 286
N ++ S+ S + + W L Y + D + P +T +
Sbjct 28 NFTLAESKASSHSVSIQWRILGSPCNFSLIY-----SSDTLGAALCPTFRIDNTTYGCNL 82
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
QDL+ T Y FRI + E + + P +
Sbjct 83 QDLQAGTIYNFRIISLD------------EERTVVLQTDPLPP---ARFGVSKEKTTSTS 127
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKS------HLQNYTVNATKLTVNLT-NDRYLAT 399
+ + W ++GK+ YEV L + +Q T NLT +Y
Sbjct 128 LHVWWTP-----SSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIA 182
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
+T + +S ++ PV D+ K N L + W+ +V++Y +
Sbjct 183 ITAVSGGKRS----FSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSGNVERY----RL 234
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
+ + D G L Y +TV ++ + L + P
Sbjct 235 MLMDKGILVHGGVVDKHATSYAFHG-LTPGYLYNLTV----MTEAAGLQNYRWKLVRTAP 289
Query 520 SKGPTVRTKKVGK-NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
+ ++ G ++W + P G + +Y I + + + TE
Sbjct 290 MEVSNLKVTNDGSLTSLKVKWQRPP-----GNVDSYNITLSHKGTIKESRVLAPWITETH 344
Query 579 LSSLTSDTLYMVRM 592
L LY V +
Sbjct 345 FKELVPGRLYQVTV 358
Score = 86.8 bits (213), Expect = 6e-16, Method: Composition-based stats.
Identities = 83/544 (15%), Positives = 162/544 (30%), Gaps = 66/544 (12%)
Query 78 QYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLS-CIV 136
Q +I ++ +F+ + + G+ E + + P+K + +S
Sbjct 686 QSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTV---PDKVQGVSVSNS 742
Query 137 NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV 196
+R W T+K++ + F K+ + C + V
Sbjct 743 ARSDYLRVSWVHATGDFDHYEVTIKNK---NNFIQTKSIPKSENECVFVQLVPGRL-YSV 798
Query 197 WVE------AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
V N G + P P +L++ N L +TW S
Sbjct 799 TVTTKSGQYEANEQGNG-----------RTIPEPVKDLTLRNRSTED--LHVTW---SGA 842
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
+ + +Y IQ D PP +T + + L P +Y + + D +
Sbjct 843 NGDVDQYEIQLLFND---MKVFPPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQ-- 897
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S G T PS I S ++ + W G + Y V+
Sbjct 898 ---SAFIEGFTV-------PSAVKNIHISPNGATDSLTVNWTP-----GGGDVDSYTVSA 942
Query 371 TRWKSHLQNYTVNATKL--TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
R + + T+ T + + + ++ G + + + V+
Sbjct 943 FRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVI 1002
Query 429 DLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
A+ +++ V W ++Y + L I + + + +L
Sbjct 1003 ADNAYSSYSLI-VSWQKAAGVAERYDI----LLLTENGILLRNTSEPATTKQHKFEDLTP 1057
Query 489 SKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
K Y I + V G + P+ +R + W
Sbjct 1058 GKKYKIQILTVSG---GLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRW-----TASE 1109
Query 549 GFIRNYTIFYRTIIGNETAV-NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
G + Y IF GN VD ++ +L +Y + + ++ E + F
Sbjct 1110 GELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFG 1169
Query 608 FTTP 611
T P
Sbjct 1170 RTVP 1173
Score = 77.6 bits (189), Expect = 4e-13, Method: Composition-based stats.
Identities = 68/398 (17%), Positives = 119/398 (30%), Gaps = 41/398 (10%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNP--SIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
P+ NL N+ L ++W+ P + IL + + S
Sbjct 377 PDKVANLEA-NNNGRMRSLVVSWSPPAGDWEQYRILLF-------NDSVVLLNITVGKEE 428
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
T+ L P +Y + + K SE G T P ++
Sbjct 429 TQYVMDDTGLVPGRQYEVEVIVESGNLK-----NSERCQGRTV-------PLAVLQLRVK 476
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT 399
H ++ ++W+T P E I+ + T + +Y+AT
Sbjct 477 HAN-ETSLSIMWQT-PVAEWEKYIISLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMAT 534
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
+T + ++ A + + + L+ WT + V+ Y +
Sbjct 535 VT---SISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQV---- 587
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
L + + R L Y + VT V G + P
Sbjct 588 LLIHENVVIKNESISSETSRYSFHS-LKSGSLYSVVVTTVSG---GISSRQVVVEGRTVP 643
Query 520 SKGPTVRTKKVGKNE-AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
S V G+N+ + W P G + NY + ++ + S E +
Sbjct 644 SSVSGVTVNNSGRNDYLSVSWLLAP-----GDVDNYEVTLSHDGKVVQSLVIAKSVRECS 698
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
SSLT LY V + + + T P QG
Sbjct 699 FSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQG 736
Score = 71.0 bits (172), Expect = 5e-11, Method: Composition-based stats.
Identities = 49/384 (13%), Positives = 108/384 (28%), Gaps = 38/384 (10%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
+ P +L + +E + L WT + YNI D + + +
Sbjct 1082 RTVPAAVTDLRI--TENSTRHLSFRWTA---SEGELSWYNIFLYNPDGNLQERAQVDPLV 1136
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
SF+ Q+L Y ++ + G + S E+ P+ +
Sbjct 1137 ---QSFSFQNLLQGRMY--KMVIVTHSG-----ELSNESFIFG-----RTVPASVSHLRG 1181
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLA 398
S+ ++ W +++ Y K + ++ + + + +Y+
Sbjct 1182 SNRNTTDSLWFNWSPASGDFDFYELILYN-PNGTKKENWKDKDLTEWRFQGLVPGRKYVL 1240
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV--KKYILE 456
+ D + + P + A + L + W P + + L+
Sbjct 1241 WVVTH----SGDLSNKVTAESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQ 1296
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
W +T + + + L + Y V V D + +
Sbjct 1297 WLPRD----ALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVR 1352
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV--NVDSSH 574
P K + + W D Y+I R + E ++
Sbjct 1353 TKPDKIQNLHCRPQNSTAIACSWIPPDSDFD-----GYSIECRKMDTQEVEFSRKLEKEK 1407
Query 575 TEYTLSSLTSDTLYMVRMAAYTDE 598
+ + L Y+V + +
Sbjct 1408 SLLNIMMLVPHKRYLVSIKVQSAG 1431
Score = 50.2 bits (118), Expect = 1e-04, Method: Composition-based stats.
Identities = 63/382 (16%), Positives = 112/382 (29%), Gaps = 64/382 (17%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKS--EWATHKFADCKAKRDTPTSCT 183
P P +S + W G + +F L+ A F ++
Sbjct 1261 PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEG---R 1317
Query 184 VDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
+ Y + + V+ + K S I + KP+ NL + S+ +
Sbjct 1318 IVYGLRPGRSYQFNVKTVSGDSWKTYSKPIF--GSVRTKPDKIQNLH--CRPQNSTAIAC 1373
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
+W P Y+I+ R D + + + + L P Y+ I+
Sbjct 1374 SWIPP---DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMM--LVPHKRYLVSIKVQ 1428
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK----IDPSHTQGYRTVQLVWKTLPPFE 358
G S+ E+++ IT DRP P + S + TV W +
Sbjct 1429 SA---GMTSEVVEDST-ITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWF----SD 1480
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
NG + + V + + L L R+ A++ V T
Sbjct 1481 TNGAVKYFTVVVREADGSDELKPEQQHPLPSYL-EYRHNASIRVY----------QTNYF 1529
Query 419 CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
A +P + K+F + ES+ + D T
Sbjct 1530 ASKCAENPNSNSKSFNIKLGAEM------ESLGG-------------------KCDPTQQ 1564
Query 479 RTYLRGNLAESKCYLITVTPVY 500
+ G L Y I++
Sbjct 1565 KFC-DGPLKPHTAYRISIRAFT 1585
Score = 47.9 bits (112), Expect = 6e-04, Method: Composition-based stats.
Identities = 27/199 (14%), Positives = 59/199 (30%), Gaps = 21/199 (11%)
Query 405 LVGKSDAAVLTIPACDFQATHPVMD----LKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
G A +T+ P ++ + + ++W S + L +
Sbjct 3 SHGAGLALWITLSLLQTGLAEPERCNFTLAESKASSHSVSIQW-RILGSPCNFSLIY--S 59
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS 520
SD +L Y + + + ++ PP+
Sbjct 60 SDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEE-----RTVVLQTDPLPPA 114
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSH--TEY 577
+ V +K + W +G + +Y + + V + S EY
Sbjct 115 RF-GVSKEKTTSTSLHVWWTPS-----SGKVTSYEVQLFDENNQKIQGVQIQESTSWNEY 168
Query 578 TLSSLTSDTLYMVRMAAYT 596
T +LT+ + Y + + A +
Sbjct 169 TFFNLTAGSKYNIAITAVS 187
>sp|P06213|INSR_HUMAN Insulin receptor OS=Homo sapiens OX=9606
GN=INSR PE=1 SV=4
Length=1382
Score = 102 bits (254), Expect = 8e-21, Method: Composition-based stats.
Identities = 89/532 (17%), Positives = 158/532 (30%), Gaps = 115/532 (22%)
Query 228 LSVINSEELSSILKLTWTNPSIKSVI--ILKYNIQYRTK--------------DASTWSQ 271
L + L W P +L + + Y+ +++W+
Sbjct 500 LKFSYIRTSFDKILLRWE-PYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTV 558
Query 272 I---PPEDTASTRSS----FTVQDLKPFTEYVFRIR--CMKEDGKGYWSDWSEEASGITY 322
+ PP + +S + ++ LKP+T+Y ++ D + + S+ T
Sbjct 559 VDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTD 618
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
PS + S + L WK PP + NG I Y V R + + +
Sbjct 619 ATNPSVPLDPISVSNSSSQ-----IILKWK--PPSDPNGNITHYLVFWERQAEDSELFEL 671
Query 383 NATKLTVNLTNDRYLATLTVRNL-----------VGK--SDAAVLTIPACDFQATHPVMD 429
+ + L + + + G+ S + + + +
Sbjct 672 DYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKT 731
Query 430 LKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED---------GTVHRT 480
+ + N+++V PR++ E S K + D T
Sbjct 732 FEDYLH-NVVFV----PRKTSSGTGAEDPRPSRKRRSLGDVGNVTVAVPTVAAFPNTSST 786
Query 481 --------------------YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK-QAPP 519
+ L Y I + D P S+ AY+ + P
Sbjct 787 SVPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMP 846
Query 520 SK------GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSS 573
GP V + N L W + NG I Y + YR E + V
Sbjct 847 EAKADDIVGP-VTHEIFENNVVHLMWQEPK--EPNGLIVLYEVSYRRYGDEELHLCVSRK 903
Query 574 H----TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT--FTT--PKFAQGEIEAIVVPV 625
H L L+ Y VR+ A + G E T + T + I+ P+
Sbjct 904 HFALERGCRLRGLSPG-NYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPL 962
Query 626 CLAFLLTTLLG-VLFCFNKRDLIKKHIWPNVP--------DPSKSHIAQWSP 668
FL + ++G + KR P+ P +P + P
Sbjct 963 IFVFLFSVVIGSIYLFLRKRQ-------PDGPLGPLYASSNPEYLSASDVFP 1007
Score = 63.0 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 21/127 (17%), Positives = 41/127 (32%), Gaps = 4/127 (3%)
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL---SSILKLTWTN 246
+F + ++A N + + P + V ++++ L W
Sbjct 814 HFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQE 873
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P + +I+ Y + YR + ++ L P Y RIR G
Sbjct 874 PKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPG-NYSVRIRATSLAG 932
Query 307 KGYWSDW 313
G W++
Sbjct 933 NGSWTEP 939
>sp|O73798|IGF1R_XENLA Insulin-like growth factor 1 receptor OS=Xenopus
laevis OX=8355 GN=igf1r PE=1 SV=1
Length=1358
Score = 102 bits (254), Expect = 9e-21, Method: Composition-based stats.
Identities = 90/503 (18%), Positives = 153/503 (30%), Gaps = 115/503 (23%)
Query 228 LSVINSEELSSILKLTWT---NPSIKSVIILKYNIQYRTK--------------DASTWS 270
L+ + ++ + +KLTW P + ++ + + Y+ +++W+
Sbjct 487 LNFTSRSKIKNRIKLTWERYRPPDYRD--LISFTVYYKEAPFRNVTEYDGQDACGSNSWN 544
Query 271 QIPPEDTASTRSS--FTVQDLKPFTEYVFRIRCM------KEDGKGYWSDWSEEASGITY 322
+ + AS S +Q LKP+T+Y ++ + G S T
Sbjct 545 MVDVDLPASKESDPGILLQGLKPWTQYAIYVKAITLTMLENRHIHGAKSK---IIYMRTD 601
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
PS S + + + W PP NG + Y V RW+ Q+
Sbjct 602 AAVPSIPQDM-----ISASNSSSQLVVKWN--PPSLPNGNLSYYIV---RWQQQPQD--- 648
Query 383 NATKLTVNLTNDRYLATLTVRNLV---GKSDAAVLTIPACDFQATHPVMDLKAFPKD--- 436
+L Y V N G D T P + A PK
Sbjct 649 ------RHLYQYNYCFKDKVPNRKYANGTIDTEGGTEPTKPEGSVGEKGHYCACPKTEAE 702
Query 437 -------------------NMLWV-EWTTPRESV----KKYILEWC---------VLSDK 463
N ++V R V + + SD
Sbjct 703 EKAEKDEAEYRKVFENFLHNSIFVPRPNRRRRDVLAVGNSTVTSYEKNSTTEDFSNFSDS 762
Query 464 APCITDW----QQEDGTVHRTYLRGNLAESKCYLITVTPVYAD----GPGSPESIKAYLK 515
++ + D RT + NL Y I + + G + + A
Sbjct 763 ERDDIEYPFYETKVDYKWERTVI-SNLQPFTLYRIDIHSCNHEAEKLGCSASNFVFARTM 821
Query 516 QAP-PSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG--NETAVNVD 571
A P V TK+ L W + NG I Y I Y+ E D
Sbjct 822 PAAGADDIPGIVNTKEEDDGVIFLGWPE--PLRPNGLILMYEIEYKHQGEVHRECVSRQD 879
Query 572 SSHT-EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT------PKFAQGEIEAIV-V 623
L L Y ++ A + G +G + P ++ +V +
Sbjct 880 YRKNGGIKLVRLPPG-NYSAQVQAISLYG--NGSWTEMVSFCVKLKPDVRNNILQMVVAI 936
Query 624 PVCLAFLLTTLLGVLFC-FNKRD 645
P+ L+FLL ++ ++ F KR+
Sbjct 937 PLALSFLLVGIISIVCFVFKKRN 959
Score = 54.9 bits (130), Expect = 4e-06, Method: Composition-based stats.
Identities = 27/149 (18%), Positives = 55/149 (37%), Gaps = 7/149 (5%)
Query 168 KFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN----ALGKVTSDHINFDPVYKVKPN 223
++ + K D TV + F + + + N LG S+ + + +
Sbjct 768 EYPFYETKVDYKWERTVISNLQPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAAGAD 827
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
+ V EE ++ L W P + +IL Y I+Y+ + + +D
Sbjct 828 DIPGI-VNTKEEDDGVIFLGWPEPLRPNGLILMYEIEYKHQGEVHRECVSRQD-YRKNGG 885
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ L P Y +++ + G G W++
Sbjct 886 IKLVRLPPG-NYSAQVQAISLYGNGSWTE 913
>sp|Q9HD43|PTPRH_HUMAN Receptor-type tyrosine-protein phosphatase
H OS=Homo sapiens OX=9606 GN=PTPRH PE=1 SV=4
Length=1115
Score = 101 bits (252), Expect = 1e-20, Method: Composition-based stats.
Identities = 66/376 (18%), Positives = 118/376 (31%), Gaps = 44/376 (12%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
PNP NL+V + +S + L+W P Y +Q +T E +T
Sbjct 30 PNPGRNLTVE--TQTTSSISLSWEVPDGLDSQNSNYWVQCTGDGGTT------ETRNTTA 81
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
++ TV L P + Y + D + G AP+ +
Sbjct 82 TNVTVDGLGPGSLYTCSV--------WVEKDGVNSSVGTVTTA---TAPNPVRNLRVEA- 129
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLT 401
Q ++ L W+ + Y V T + T +TV+ L +
Sbjct 130 QTNSSIALTWEVPDGPDPQNS--TYGVEYTGDGGRAGTRSTAHTNITVDGLEPGCLYAFS 187
Query 402 V---RNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEW 457
+ +N + S A +PV +L+ + + + W P + + +
Sbjct 188 MWVGKNGINSSRETRNATT-----AHNPVRNLRVEAQTTSSISLSWEVPDGTDPQNST-Y 241
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
CV T+ + T L Y +V + G S++
Sbjct 242 CVQCTGDGGRTETRN---TTDTRVTVDGLGPGSLYTCSVWV---EKDGVNSSVEIVTSAT 295
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLP-VDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
P+ + + + L W+ D QN Y + Y G ++HT
Sbjct 296 APNPVRNLTVEAQTNSSIALTWEVPDGPDPQNST---YGVEYTGDGGRAGTR--STAHTN 350
Query 577 YTLSSLTSDTLYMVRM 592
T+ L LY+ +
Sbjct 351 ITVDRLEPGCLYVFSV 366
Score = 86.1 bits (211), Expect = 9e-16, Method: Composition-based stats.
Identities = 91/521 (17%), Positives = 147/521 (28%), Gaps = 64/521 (12%)
Query 83 NRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKM 142
N T + VT D TC++ + N + S P +NL+ +
Sbjct 256 NTTDTRVT-VDGLGPGSLYTCSVW-VEKDGVNSSVEIVTSATAPNPVRNLTVEAQTNSSI 313
Query 143 RCEWD--GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
W+ G + T + A VWV
Sbjct 314 ALTWEVPDGPDPQNSTYGVEYTGDGGRAGTRSTAHT---NITVDRLEPGCLYVFSVWV-G 369
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQ 260
+N + PNP NL + + +S + L W P Y ++
Sbjct 370 KNGINSSRETRN-----ATTAPNPVRNLHME--TQTNSSIALCWEVPDGPYPQDYTYWVE 422
Query 261 YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
Y T E +T +S T + L+P T Y F + K +G + S
Sbjct 423 YTGDGGGT------ETRNTTNTSVTAERLEPGTLYTFSVWAEKNGARGSRQNVSIS---T 473
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL-TRWKSHLQN 379
S + W T+ L W + Y V+ + +
Sbjct 474 VPNAVTSLSKQDW---------TNSTIALRWTAPQGPGQSSY--SYWVSWVREGMTDPRT 522
Query 380 YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNM 438
+ + T +T+ L LTV + T+ A A + V DL+ N
Sbjct 523 QSTSGTDITLKELEAGSLYHLTVWAERNEVRGYNSTLTAAT--APNEVTDLQNETQTKNS 580
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCIT------DWQQEDGTVHRT-YLRGNLAESKC 491
+ + W P + + + W + K +W + + T Y L
Sbjct 581 VMLWWKAPGDPHSQLYVYWVQWASKGHPRRGQDPQANWVNQTSRTNETWYKVEALEPGTL 640
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE----AVLEWDQLPVDVQ 547
Y TV D S +S+ A TV L W Q
Sbjct 641 YNFTVWAERNDVASSTQSLCAST------YPDTVTITSCVSTSAGYGVNLIWSCP----Q 690
Query 548 NGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLY 588
G Y F + G + + S ++ L Y
Sbjct 691 GG----YEAFELEVGGQRGSQDRSSCGEAVSVLGLGPARSY 727
Score = 37.1 bits (84), Expect = 0.89, Method: Composition-based stats.
Identities = 26/155 (17%), Positives = 48/155 (31%), Gaps = 26/155 (17%)
Query 513 YLKQAPPSKGP--TVRTKKVGKNEAVLEWDQLP-VDVQNGFIRNYTIFYRTIIGNETAVN 569
+ P+ P + + + L W+ +D QN NY + + T
Sbjct 22 WTGARAPAPNPGRNLTVETQTTSSISLSWEVPDGLDSQNS---NYWV--QCTGDGGTTET 76
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAF 629
+++ T T+ L +LY + + ++ G + T TT V +
Sbjct 77 RNTTATNVTVDGLGPGSLYTCSV--WVEKDGVNSSVGTVTTATAPNPVRNLRVEAQTNSS 134
Query 630 LLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIA 664
+ T P+ PDP S
Sbjct 135 IALT----------------WEVPDGPDPQNSTYG 153
>sp|P16620|PTP69_DROME Tyrosine-protein phosphatase 69D OS=Drosophila
melanogaster OX=7227 GN=Ptp69D PE=1 SV=2
Length=1462
Score = 101 bits (251), Expect = 2e-20, Method: Composition-based stats.
Identities = 80/500 (16%), Positives = 151/500 (30%), Gaps = 86/500 (17%)
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL---QNYTVNATKLTVN 390
ID + G + L W + N I + +TL + +N + +
Sbjct 239 VSIDFAKAVGANKIYLNWTV---NDGNDPIQKFFITLQEAGTPTFTYHKDFINGSHTSYI 295
Query 391 L----TNDRYLATLTVRNLVGKSDAA--VLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
L N Y + +N +G I + + + + W
Sbjct 296 LDHFKPNTTYFLRIVGKNSIGNGQPTQYPQGITTLSYDPIFIPKVETTGSTASTITIGWN 355
Query 445 TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT----YLRGNLAESKCYLITVTPVY 500
P + YI + ++ ++ + +E + Y+ L + Y V
Sbjct 356 PPPPDLIDYIQYYELIVSESGEVPKVIEEAIYQQNSRNLPYMFDKLKTATDYEFRVRACS 415
Query 501 A--DGPGS-PESIKAYLKQAPPSKGPTVRTK-----KVGKNEAVLEWDQLPVDVQNGFIR 552
G E++ +K + + N + WD NG +
Sbjct 416 DLTKTCGPWSENVNGTTMDGVATKPTNLSIQCHHDNVTRGNSIAINWDVPKT--PNGKVV 473
Query 553 NYTIFY---------RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+Y I R + G + +D H + S++ +T Y V ++A T
Sbjct 474 SYLIHLLGNPMSTVDREMWGPKI-RRIDEPHHKTLYESVSPNTNYTVTVSAITR------ 526
Query 604 PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHI 663
GE P + L+ D I + +W V SK +
Sbjct 527 --------HKKNGE------PATGSCLMPVST--------PDAIGRTMWSKVNLDSKYVL 564
Query 664 AQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEG 723
+ P R+ ++Y + ND K P+ K +E +
Sbjct 565 KLYLPKISERNGPICCYRLY----------LVRINNDNKELPDPEKLNIATYQEVHSDNV 614
Query 724 HSSGIGGSSCMSSS--RPSISSSDENESSQNT-----SSTVQYSTVVHSGYRHQ-----V 771
S + +SS RP I DE S+N + + + + + + +
Sbjct 615 TRSSAYIAEMISSKYFRPEIFLGDEKRFSENNDIIRDNDEICRKCLEGTPFLRKPEIIHI 674
Query 772 PSVQVFSRSESTQPLLDSEE 791
P S S+S P+L ++
Sbjct 675 PPQGSLSNSDSELPILSEKD 694
Score = 96.5 bits (238), Expect = 7e-19, Method: Composition-based stats.
Identities = 93/628 (15%), Positives = 195/628 (31%), Gaps = 83/628 (13%)
Query 24 LLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTII- 82
L C S + ++ N + C + + + + N NH +
Sbjct 21 LCAICVQGSVKQEWAEIGKNVSLECASENEAVAWKLGNQTI---NKNHTRYKIRTEPLKS 77
Query 83 -------NRTASSVTFTDIASL---NIQLTCNILTFGQLEQN---VYGIT--IISGLPPE 127
N + + + ++ +L NI+ + N Q QN + + + S +
Sbjct 78 NDDGSENNDSQDFIKYKNVLALLDVNIKDSGNYTCTAQTGQNHSTEFQVRPYLPSKVLQS 137
Query 128 KPKNLSCIVNEGKKMRCEWD--GGRETHLETNFTLKSEWATHKFA--DCKAKRDTPTSCT 183
P + + + + C + ET TN LK +F D +
Sbjct 138 TPDRIKRKIKQDVMLYCLIEMYPQNET---TNRNLKWLKDGSQFEFLDTFSSISKLNDTH 194
Query 184 VDYSTVYFV-------NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
++++ + + V + L ++TS I + P ++ +
Sbjct 195 LNFTLEFTEVYKKENGTYKCTVFDDTGL-EITSKEITLFVMEV----PQVSIDFAKAVGA 249
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
+ + L WT + + I K+ I + T + + +S+ + KP T Y
Sbjct 250 NK-IYLNWTV-NDGNDPIQKFFITLQEAGTPT-FTYHKDFINGSHTSYILDHFKPNTTYF 306
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
RI G G + + T P P + T+ + W PP
Sbjct 307 LRIVGKNSIGNGQPTQY--PQGITTLSYDPIFIPKVE-----TTGSTASTITIGWNPPPP 359
Query 357 FEANGKILDYEVTLTRWKS-----HLQNYTVNATKLTV----NLTNDRYLATLTVRNLVG 407
+ I YE+ ++ Y N+ L T Y + + +
Sbjct 360 DLID-YIQYYELIVSESGEVPKVIEEAIYQQNSRNLPYMFDKLKTATDYEFRVRACSDLT 418
Query 408 K--SDAAVLTIPACDFQATHPVMDLK------AFPKDNMLWVEWTTPRESVKKYILEWCV 459
K + +L + N + + W P ++ ++ + +
Sbjct 419 KTCGPWSENVNGTTMDGVATKPTNLSIQCHHDNVTRGNSIAINWDVP-KTPNGKVVSYLI 477
Query 460 L--------SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY-ADGPGSPESI 510
D+ ++ D H+T L +++ + Y +TV+ + G P +
Sbjct 478 HLLGNPMSTVDREMWGPKIRRIDEPHHKT-LYESVSPNTNYTVTVSAITRHKKNGEPATG 536
Query 511 KAYLKQAPPSKGPTVRTKKVGKNE-AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
+ + P KV + VL+ + +NG I Y ++ I + +
Sbjct 537 SCLMPVSTPDAIGRTMWSKVNLDSKYVLKLYLPKISERNGPICCYRLYLVRINNDNKELP 596
Query 570 VDSSHTEYTLS-----SLTSDTLYMVRM 592
T ++T + Y+ M
Sbjct 597 DPEKLNIATYQEVHSDNVTRSSAYIAEM 624
>sp|P35590|TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 OS=Homo
sapiens OX=9606 GN=TIE1 PE=1 SV=1
Length=1138
Score = 100 bits (249), Expect = 3e-20, Method: Composition-based stats.
Identities = 62/332 (19%), Positives = 104/332 (31%), Gaps = 38/332 (11%)
Query 210 DHINFDPVYKVKPNP---PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA 266
D F KV P P P L+ + S L ++ I + YR +D+
Sbjct 435 DSRRFKVNVKVPPVPLAAPRLLT-----KQSRQLVVSPLVSFSGDGPISTVRLHYRPQDS 489
Query 267 S-TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
+ WS I + T+ +L+P T Y R++ + G+G W T D
Sbjct 490 TMDWSTI----VVDPSENVTLMNLRPKTGYSVRVQ-LSRPGEGGEGAWGPPTLMTT--DC 542
Query 326 PSKAPSFWYKIDPSHTQGYRTVQLVWK-TLPPFEANGKILDYEVTLTRWKSH-------- 376
P W ++ H +G +++ W L P G L W
Sbjct 543 PEPLLQPW--LEGWHVEGTDRLRVSWSLPLVPGPLVGDGF----LLRLWDGTRGQERREN 596
Query 377 LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-K 435
+ + LT Y + + + A+ L A
Sbjct 597 VSSPQARTALLTGLTPGTHYQLDVQLYHCTLLGPASPPAHVLLPPSGPPAPRHLHAQALS 656
Query 436 DNMLWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
D+ + + W P + KY++E V W D + + L S Y
Sbjct 657 DSEIQLTWKHPEALPGPISKYVVE--VQVAGGAGDPLWIDVDRPEETSTIIRGLNASTRY 714
Query 493 LITVTP-VYADGPGSPESIKAYLKQAPPSKGP 523
L + + G S ++ L ++GP
Sbjct 715 LFRMRASIQGLGDWSNTVEESTLGNGLQAEGP 746
Score = 92.2 bits (227), Expect = 1e-17, Method: Composition-based stats.
Identities = 69/435 (16%), Positives = 116/435 (27%), Gaps = 56/435 (13%)
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
C G S + + P AP T+ R + + L F +
Sbjct 426 CRVSTSGGQDSRRFKVNVKVPP--VPLAAPRLL-------TKQSRQLVVS--PLVSFSGD 474
Query 361 GKILDYEVTLTRWKSH--LQNYTVNATKLTVN---LTNDRYLATLT-VRNLVG----KSD 410
G I + S V+ ++ Y + R G
Sbjct 475 GPISTVRLHYRPQDSTMDWSTIVVDPSENVTLMNLRPKTGYSVRVQLSRPGEGGEGAWGP 534
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP----RESVKKYILEWCVLSDKAPC 466
++T C P ++ + L V W+ P ++L +
Sbjct 535 PTLMT-TDCPEPLLQPWLEGWHVEGTDRLRVSWSLPLVPGPLVGDGFLLRLWDGTRGQER 593
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITV--TPVYADGPGSPESIKAYLKQAPPSKGPT 524
+ RT L L Y + V GP SP L + P
Sbjct 594 R---ENVSSPQARTALLTGLTPGTHYQLDVQLYHCTLLGPASP-PAHVLLPPSGPPAPRH 649
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD---SSHTEYTLSS 581
+ + + +E L W + G I Y + + G + +D T +
Sbjct 650 LHAQALSDSEIQLTWKH--PEALPGPISKYVVEVQVAGGAGDPLWIDVDRPEETSTIIRG 707
Query 582 LTSDTLYMVRMAAYTDEGGK----------------DGPEFTFTTPK--FAQGEIEAIVV 623
L + T Y+ RM A G +GP + Q I A+V
Sbjct 708 LNASTRYLFRMRASIQGLGDWSNTVEESTLGNGLQAEGPVQESRAAEEGLDQQLILAVVG 767
Query 624 PVC-LAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQM 682
V + L L C + L ++ + + I Q+S T
Sbjct 768 SVSATCLTILAALLTLVCIRRSCLHRRRTFTYQSGSGEETILQFSSGTLTLTRRPKLQPE 827
Query 683 YSDGNFTDVSVVEIE 697
+ + E
Sbjct 828 PLSYPVLEWEDITFE 842
Score = 68.0 bits (164), Expect = 4e-10, Method: Composition-based stats.
Identities = 35/184 (19%), Positives = 64/184 (35%), Gaps = 16/184 (9%)
Query 142 MRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRDTP---TSCTVDYSTVYFVNIEVW 197
+R W L + L W + + + +P T+ + ++V
Sbjct 562 LRVSWSLPLVPGPLVGDGFLLRLWDGTRGQERRENVSSPQARTALLTGLTPGTHYQLDVQ 621
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY 257
+ LG + P PP + S ++LTW +P I KY
Sbjct 622 LYHCTLLGPASPPAHVLLP----PSGPPAPRHLHAQALSDSEIQLTWKHPEALPGPISKY 677
Query 258 NIQYRTKDAST---WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
++ + + W + +S ++ L T Y+FR+R G G WS+
Sbjct 678 VVEVQVAGGAGDPLWIDVDR----PEETSTIIRGLNASTRYLFRMRAS-IQGLGDWSNTV 732
Query 315 EEAS 318
EE++
Sbjct 733 EEST 736
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 33/210 (16%), Positives = 65/210 (31%), Gaps = 22/210 (10%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
+ L+++W+ P + ++ R D + + ++ + + L P T Y
Sbjct 559 TDRLRVSWSLPLVP-GPLVGDGFLLRLWDGTRGQERRENVSSPQARTALLTGLTPGTHYQ 617
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
++ S A + P P + + +QL WK P
Sbjct 618 LDVQLY---HCTLLGPASPPAHVL----LPPSGPPAPRHLH-AQALSDSEIQLTWKH--P 667
Query 357 FEANGKILDYEVTLT-------RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
G I Y V + + +T + + RYL + ++ G
Sbjct 668 EALPGPISKYVVEVQVAGGAGDPLWIDVDRPEETSTIIRGLNASTRYLFRMRA-SIQGLG 726
Query 410 DAAVLT---IPACDFQATHPVMDLKAFPKD 436
D + QA PV + +A +
Sbjct 727 DWSNTVEESTLGNGLQAEGPVQESRAAEEG 756
>sp|Q8N9C0|IGS22_HUMAN Immunoglobulin superfamily member 22 OS=Homo
sapiens OX=9606 GN=IGSF22 PE=2 SV=2
Length=903
Score = 100 bits (248), Expect = 3e-20, Method: Composition-based stats.
Identities = 55/317 (17%), Positives = 94/317 (30%), Gaps = 22/317 (7%)
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
+Y FR KG S+ S + D PS + +++ ++
Sbjct 582 KYTFR-------AKGTESEASVFIADPPTID-PSVLEALAAHAITVKVGHTAHIKVPFRG 633
Query 354 LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAV 413
P + EVT S + ++ + D L L ++N G S A
Sbjct 634 KPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHG-SATAT 692
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ-- 471
L + + + K+ + + W P + +L + ++ + W
Sbjct 693 LHLSVLEPPGFASQPQVTDVTKE-AVTITWNAPTQDGGAPVLGY-IVERRKKGSNLWVPV 750
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG----SPESIKAYLKQAPPSKGPTVRT 527
+D L E Y V V GPG S+ A PP +
Sbjct 751 NKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHV 810
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSD 585
+ L W + Y + R E + S T YT+ L
Sbjct 811 SDSSNSSISLAWREPAEGDPPS---GYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIER 867
Query 586 TLYMVRMAAYTDEGGKD 602
Y R+ A + G +
Sbjct 868 QKYFFRIRAVNEAGVGE 884
Score = 93.0 bits (229), Expect = 6e-18, Method: Composition-based stats.
Identities = 39/196 (20%), Positives = 66/196 (34%), Gaps = 11/196 (6%)
Query 233 SEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
++ + +TW P+ +L Y ++ R K ++ W +P + TV L
Sbjct 710 TDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLW--VPVNKDPIQGTKCTVDGLLE 767
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
TEY FR+ + + G G S S P K P + S + L W
Sbjct 768 DTEYEFRVIAVNKAGPGQPSVPSSSVVAKD----PVKPPGLVQDLHVSDSSNSSI-SLAW 822
Query 352 -KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLVGK 408
+ +G IL+ T+ S ++ T TV + +Y + N G
Sbjct 823 REPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGV 882
Query 409 SDAAVLTIPACDFQAT 424
+ L
Sbjct 883 GEPVELDKGVRAMPPP 898
Score = 81.8 bits (200), Expect = 2e-14, Method: Composition-based stats.
Identities = 39/206 (19%), Positives = 64/206 (31%), Gaps = 17/206 (8%)
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH----LQNYTVN 383
+ P F + + V + W P + +L Y V + S+ + +
Sbjct 699 EPPGFASQPQVTDVTKE-AVTITW-NAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQ 756
Query 384 ATKLTVNLTN--DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP----KDN 437
TK TV+ Y + N G +V + P ++ ++
Sbjct 757 GTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSNS 816
Query 438 MLWVEWTTPRE--SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLIT 495
+ + W P E YILE K GT Y G L E + Y
Sbjct 817 SISLAWREPAEGDPPSGYILEMRAEDTKEWSKCTKIPISGTC---YTVGGLIERQKYFFR 873
Query 496 VTPVYADGPGSPESIKAYLKQAPPSK 521
+ V G G P + ++ PP
Sbjct 874 IRAVNEAGVGEPVELDKGVRAMPPPG 899
Score = 81.1 bits (198), Expect = 3e-14, Method: Composition-based stats.
Identities = 46/257 (18%), Positives = 79/257 (31%), Gaps = 13/257 (5%)
Query 63 NYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQL-EQNVYGITII 121
+ W + + +E+ + R T + +L + +
Sbjct 637 PKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLS 696
Query 122 SGLPPEKPKNLSCIVNEGKKMRCEWD-GGRETHLET--NFTLKSEWATHKFADCKAKRDT 178
PP + + W+ ++ + + ++ +
Sbjct 697 VLEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQ 756
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPP---HNLSVINSEE 235
T CTVD E V A N G + V K PP +L V +S
Sbjct 757 GTKCTVDGLLE-DTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDSSN 815
Query 236 LSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
S L W P+ Y ++ R +D WS+ + T +TV L +Y
Sbjct 816 SSIS--LAWREPAEGD-PPSGYILEMRAEDTKEWSKCTKIPISGT--CYTVGGLIERQKY 870
Query 296 VFRIRCMKEDGKGYWSD 312
FRIR + E G G +
Sbjct 871 FFRIRAVNEAGVGEPVE 887
Score = 39.5 bits (90), Expect = 0.19, Method: Composition-based stats.
Identities = 17/107 (16%), Positives = 33/107 (31%), Gaps = 6/107 (6%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLK-SEWATHKFADCKAKRDTPTSC 182
PP ++L + + W E + + L+ T +++ C K +C
Sbjct 800 KPPGLVQDLHVSDSSNSSISLAWREPAEGDPPSGYILEMRAEDTKEWSKC-TKIPISGTC 858
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS 229
+ + A N G + V+ PP L+
Sbjct 859 YTVGGLIERQKYFFRIRAVNEAGVGEP----VELDKGVRAMPPPGLT 901
>sp|Q1KL86|EPHA2_MACFA Ephrin type-A receptor 2 OS=Macaca fascicularis
OX=9541 GN=EPHA2 PE=2 SV=1
Length=976
Score = 100 bits (248), Expect = 4e-20, Method: Composition-based stats.
Identities = 68/359 (19%), Positives = 121/359 (34%), Gaps = 44/359 (12%)
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK----YILE----WCVLS 461
+++P + L A + + WT P++S + Y + W
Sbjct 317 PQDPMSMPCT--RPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCWPESG 374
Query 462 DKAPCITD--WQQEDGTVHRT-YLRGNLAESKCYLITVTPVYA-DGPGSPESIKAYLKQA 517
+ PC + + + + RT +L Y TV G + S +
Sbjct 375 ECGPCESSVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSFRTASVSI 434
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY 577
++ P VR + + W P Q + Y + YR + + +
Sbjct 435 NQTEPPKVRLEGRSTTSLSVSWSIPPP--QQSRVWKYEVTYRKKGDSNSYNVRRTEGFSV 492
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGP---EFTFTTPKFAQGEIEAIVVPVCLAFLLTTL 634
TL L DT Y+V++ A T EG G EF +P+ + V VC+ LL
Sbjct 493 TLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGSLAVIGGVAVCVVLLLLLA 552
Query 635 LGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSP--HTPPRHNFNSKDQ----------- 681
F +R ++ P D S Q P H + +Q
Sbjct 553 GAGFFIHRRRKNLRARQSPE--DVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHP 610
Query 682 -------MYSDGNFTDVSVVEIEAND-KKPFPEDLKSLDL--FKKEKINTEGHSSGIGG 730
+ G F +V ++ + KK P +K+L +K++++ G + +G
Sbjct 611 SCVTRQKVIGAGEFGEVYKGTLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQ 669
Score = 94.9 bits (234), Expect = 1e-18, Method: Composition-based stats.
Identities = 47/202 (23%), Positives = 83/202 (41%), Gaps = 23/202 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADCKAK---R 176
PP P L+ + K + W GRE + + + + + C++
Sbjct 328 PPSAPHYLTAVGMGAK-VELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCESSVRYS 386
Query 177 DTPTSCTVDYSTVY----FVNIEVWVEAENAL-GKVTSDHINFDPVYKVKPNPPHNLSVI 231
+ P T TV +N VEA N + G VTS V + PP V
Sbjct 387 EPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSFRTASVSINQTEPP---KVR 443
Query 232 NSEELSSILKLTWTNPSIKSVIILKYNIQYRTK-DASTWSQIPPEDTASTRSSFTVQDLK 290
++ L ++W+ P + + KY + YR K D+++++ E S T+ DL
Sbjct 444 LEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNSYNVRRTEGF-----SVTLDDLA 498
Query 291 PFTEYVFRIRCMKEDGKGYWSD 312
P T Y+ +++ + ++G+G S
Sbjct 499 PDTTYLVQVQALTQEGQGAGSK 520
Score = 64.5 bits (155), Expect = 4e-09, Method: Composition-based stats.
Identities = 40/231 (17%), Positives = 76/231 (33%), Gaps = 27/231 (12%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNI----------QYRT 263
DP+ PP + + + + ++L WT P + Y++ +
Sbjct 319 DPMSMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCWPESGECGP 378
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
++S PP TR+S TV DL+P Y F + S AS +
Sbjct 379 CESSVRYSEPPHGL--TRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSFRTASVSINQ 436
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN 383
P K +++ T ++ + W PP ++ ++ YEVT +
Sbjct 437 TEPPK-----VRLEGRSTT---SLSVSWSIPPPQQS--RVWKYEVTYRKKGDSNSYNVRR 486
Query 384 ATKLTVNL----TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
+V L + YL + G+ + + + +
Sbjct 487 TEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGSLAV 537
>sp|Q32MD9|CDON_MOUSE Cell adhesion molecule-related/down-regulated
by oncogenes OS=Mus musculus OX=10090 GN=Cdon PE=1 SV=2
Length=1250
Score = 100 bits (248), Expect = 4e-20, Method: Composition-based stats.
Identities = 51/279 (18%), Positives = 93/279 (33%), Gaps = 16/279 (6%)
Query 168 KFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENA-LGKVTSDHINFDPVYKVKPNPPH 226
F K K + + + V V EA N+ G V +D + P P
Sbjct 666 TFRTSKEKMASSKNTQASFPPVGVPKRPVTAEASNSNFGVVLTDSSR----HSGVPEAPD 721
Query 227 NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 286
++ + E S + +TW + I + ++Y+ S W + ED ++ S V
Sbjct 722 RPTISMASETS--VYVTWIPRANGGSPITAFKVEYKRMRTSDW-LVAAEDIPPSKLSVEV 778
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
+ L+P + Y FR+ + G+ + S S + +R S P I +
Sbjct 779 RSLEPGSIYKFRVIAINHYGESFRSSASRPYQVAGFPNRFSNRPITGPHIAYTEAVSDTQ 838
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKSHL----QNYTVNATK----LTVNLTNDRYLA 398
+ L W +P N I + + S + V +K + Y
Sbjct 839 IMLKWTYVPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHTIGHLQPETSYDI 898
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN 437
+ N G+S+ + + I + D
Sbjct 899 KMQCFNEGGESEFSNVMICETKVKRVPGASDYPVKELST 937
Score = 91.8 bits (226), Expect = 2e-17, Method: Composition-based stats.
Identities = 64/434 (15%), Positives = 123/434 (28%), Gaps = 108/434 (25%)
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR-- 372
+ +R + P + P T T LVW+ + I Y V +
Sbjct 558 HPSGVELPAERNASVPDAPNILSPPQTHMPDTYNLVWRA--GRDGGMPINAYFVKYRKLD 615
Query 373 --------WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ-- 422
W + + N LT + Y + R+ VG+ A+LT +
Sbjct 616 DGSGAVGSWHTVRVPGSENELHLTELEPSSLYEVLMVARSAVGEGQPAMLTFRTSKEKMA 675
Query 423 -----------------------------------------ATHPVMDLKAFPKDNMLWV 441
P + + ++V
Sbjct 676 SSKNTQASFPPVGVPKRPVTAEASNSNFGVVLTDSSRHSGVPEAPDRPTISMASETSVYV 735
Query 442 EWTT---PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
W + + +E+ + + + + + +R L Y V
Sbjct 736 TWIPRANGGSPITAFKVEYKRM-RTSDWLVAAEDIPPSKLSVEVRS-LEPGSIYKFRVIA 793
Query 499 VYADGPG------SPESIKAYLKQ--APPSKGPTVR-TKKVGKNEAVLEWDQLPVDVQNG 549
+ G P + + + P GP + T+ V + +L+W +P N
Sbjct 794 INHYGESFRSSASRPYQVAGFPNRFSNRPITGPHIAYTEAVSDTQIMLKWTYVPSSNNNT 853
Query 550 FIRNYTIFYRTIIGNETA----VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE------- 598
I+ + I+YR + + V+ S +T+ L +T Y ++M + +
Sbjct 854 PIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHTIGHLQPETSYDIKMQCFNEGGESEFSN 913
Query 599 ------------GGKDGPEFTFTTPKFAQG----------------EIEAIVVPVCLAFL 630
G D P +TP + G + IV V +
Sbjct 914 VMICETKVKRVPGASDYPVKELSTPPSSSGNAGNVGPATSPARSSDMLYLIVGCVLGVMV 973
Query 631 LTTLLGVLFCFNKR 644
L ++ + C K
Sbjct 974 LILMVFIALCLWKS 987
Score = 74.5 bits (181), Expect = 4e-12, Method: Composition-based stats.
Identities = 46/352 (13%), Positives = 92/352 (26%), Gaps = 67/352 (19%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST-----WSQIPPED 276
P+ P+ LS + L W + I Y ++YR D + W +
Sbjct 573 PDAPNILS-PPQTHMPDTYNLVWRAGRDGGMPINAYFVKYRKLDDGSGAVGSWHTVR--- 628
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY----------------------WSDWS 314
+ + + +L+P + Y + G+G +
Sbjct 629 VPGSENELHLTELEPSSLYEVLMVARSAVGEGQPAMLTFRTSKEKMASSKNTQASFPPVG 688
Query 315 EEASGITYEDRPS------------KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
+T E S +V + W +P
Sbjct 689 VPKRPVTAEASNSNFGVVLTDSSRHSGVPEAPDRPTISMASETSVYVTW--IPRANGGSP 746
Query 363 ILDYEVTLTR-----WKSHLQNYTVNATKLTVNLTNDR--YLATLTVRNLVGKS------ 409
I ++V R W ++ + + V Y + N G+S
Sbjct 747 ITAFKVEYKRMRTSDWLVAAEDIPPSKLSVEVRSLEPGSIYKFRVIAINHYGESFRSSAS 806
Query 410 -DAAVLTIPA--CDFQATHPVMDLKAFPKDNMLWVEWTTPRES-----VKKYILEWCVLS 461
V P + T P + D + ++WT S ++ + + +
Sbjct 807 RPYQVAGFPNRFSNRPITGPHIAYTEAVSDTQIMLKWTYVPSSNNNTPIQGFYIYYRPTD 866
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
+G+ + G+L Y I + G ++
Sbjct 867 SDNDSDYKRDVVEGSKQW-HTIGHLQPETSYDIKMQCFNEGGESEFSNVMIC 917
Score = 71.8 bits (174), Expect = 2e-11, Method: Composition-based stats.
Identities = 37/198 (19%), Positives = 71/198 (36%), Gaps = 10/198 (5%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTSCT 183
PE P + + + W T F ++ + A+ P+ +
Sbjct 716 VPEAPDRPTISMASETSVYVTWIPRANGGSPITAFKVEYKRMRTSDWLVAAEDIPPSKLS 775
Query 184 VDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPN-----PPHNLSVINSEELS 237
V+ ++ + V A N G+ + PN P + +E +S
Sbjct 776 VEVRSLEPGSIYKFRVIAINHYGESFRSSASRPYQVAGFPNRFSNRPITGPHIAYTEAVS 835
Query 238 -SILKLTWT--NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ + L WT S + I + I YR D+ S + ++ T+ L+P T
Sbjct 836 DTQIMLKWTYVPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHTIGHLQPETS 895
Query 295 YVFRIRCMKEDGKGYWSD 312
Y +++C E G+ +S+
Sbjct 896 YDIKMQCFNEGGESEFSN 913
>sp|B2RU80|PTPRB_MOUSE Receptor-type tyrosine-protein phosphatase
beta OS=Mus musculus OX=10090 GN=Ptprb PE=1 SV=1
Length=1998
Score = 100 bits (248), Expect = 5e-20, Method: Composition-based stats.
Identities = 78/494 (16%), Positives = 147/494 (30%), Gaps = 53/494 (11%)
Query 125 PPEKPKNL-SCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
PEK +NL S K W L +E K +T +
Sbjct 377 VPEKVRNLVSYNEIWMKSFTVNWTPPAGDWEHYRIVLFNESLV-LLNTTVGKEETHYALD 435
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
+ E+ V E+ G + + + P L V ++ E S L +T
Sbjct 436 G-LELIPGRQYEIEVIVES--GNLRNSERC---QGRTVPLAVLQLRVKHANETS--LGIT 487
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
W P + KY I ++ + + + FT DL P Y + M
Sbjct 488 WRAPLGEWE---KYIISLMDREL----LVIHKSLSKDAKEFTFTDLMPGRNYKATVTSMS 540
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
D K S G T P+ + ++ ++ W +A G +
Sbjct 541 GDLKQ-----SSSIKGRTV-------PAQVTDLHVNNQGMTSSLFTNW-----TKALGDV 583
Query 364 LDYEV--TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
Y+V ++ + + ++ + L ++ V + G + +
Sbjct 584 EFYQVLLIHENVVVKNESVSSDTSRYSFRALKPGSLYSVVVTTVSGGISSRQVVAEGRTV 643
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
++ + + +++ L V W V Y++ S D
Sbjct 644 PSSVSGVTVNNSGRNDYLSVSWLPAPGEVDHYVV-----SLSHEGKVDQFLIIAKSVSEC 698
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE-AVLEWD 540
+L + Y +TVT G+ S ++ P K + +++ + W
Sbjct 699 SFSSLTPGRLYNVTVT----TKSGNYASHSFTEERTVPDKVQGISVSNSARSDYLKVSWV 754
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD--E 598
G +Y + + + S E L LY V ++ + E
Sbjct 755 H-----ATGDFDHYEVTIKNRESFIQTKTIPKSENECEFIELVPGRLYSVTVSTKSGQYE 809
Query 599 GGKDGPEFTFTTPK 612
+ G T P
Sbjct 810 ASEQGTGRTIPEPV 823
Score = 100 bits (248), Expect = 5e-20, Method: Composition-based stats.
Identities = 65/444 (15%), Positives = 128/444 (29%), Gaps = 51/444 (11%)
Query 155 ETNFTLKSEWATHKFADCKA-KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN 213
NF+L T C + D T + V+ D
Sbjct 51 PCNFSLIYSSDTSGPMWCHPIRIDNFTYGCNPKDLQAGTVYNFRI--------VSLDGEE 102
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
V + P PP V + S+ L++ WT S + Y +Q + ++
Sbjct 103 STLVLQTDPLPPARFEVNREKTASTTLQVRWTP---SSGKVSWYEVQLFDHNNQKIQEVQ 159
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
++ ++T S +T +L Y I + + + + I PS
Sbjct 160 VQE-STTWSQYTFLNLTEGNSYKVAITAVSGEKRSFP-------VYINGSTVPSPVKDLG 211
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN--ATKLTVNL 391
+P+ ++ + W +G + Y + L + +Q+ V+ T +
Sbjct 212 ISPNPN------SLLISW-----SRGSGNVEQYRLVLMDKGAIVQDTNVDRRDTSYAFHE 260
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK 451
+L LT+ + + + + L V+W P V
Sbjct 261 LTPGHLYNLTIVTMA-SGLQNSRWKLVRTAPMEVSNLKVTNDGRLTSLNVKWQKPPGDVD 319
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
Y + LS + + +L + Y +T++ + + + K
Sbjct 320 SYSI---TLSHQGTIKESKTLAPPVTETQFK--DLVPGRLYQVTISCISGE----LSAEK 370
Query 512 AYLKQAPPSKGPTVRTKKVGK-NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
+ + P K + + + W G +Y I V
Sbjct 371 SAAGRTVPEKVRNLVSYNEIWMKSFTVNWTPP-----AGDWEHYRIVLFNESLVLLNTTV 425
Query 571 DSSHTEYTLSSLT--SDTLYMVRM 592
T Y L L Y + +
Sbjct 426 GKEETHYALDGLELIPGRQYEIEV 449
Score = 94.5 bits (233), Expect = 3e-18, Method: Composition-based stats.
Identities = 71/374 (19%), Positives = 123/374 (33%), Gaps = 50/374 (13%)
Query 227 NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 286
N +++ S S + W + L Y+ W P +
Sbjct 28 NFTLLESRVSSLSASIQWRTFASPCNFSLIYS---SDTSGPMWCH--PIRIDNFTYGCNP 82
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
+DL+ T Y FRI + E S + + P F + + + T
Sbjct 83 KDLQAGTVYNFRIVSLDG-----------EESTLVLQTDPLPPARFEVNREKTAST---T 128
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKS------HLQNYTVNATKLTVNLT-NDRYLAT 399
+Q+ W ++GK+ YEV L + +Q T + +NLT + Y
Sbjct 129 LQVRWTP-----SSGKVSWYEVQLFDHNNQKIQEVQVQESTTWSQYTFLNLTEGNSYKVA 183
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
+T + +S + PV DL P N L + W+ +V++Y L V
Sbjct 184 ITAVSGEKRS----FPVYINGSTVPSPVKDLGISPNPNSLLISWSRGSGNVEQYRL---V 236
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
L DK + D D L Y +T+ V K + P
Sbjct 237 LMDKGAIVQD-TNVDRRDTSYAFHE-LTPGHLYNLTI--VTMASGLQNSRWKLV--RTAP 290
Query 520 SKGPTVRTKKVGK-NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
+ ++ G+ ++W + P G + +Y+I + + + TE
Sbjct 291 MEVSNLKVTNDGRLTSLNVKWQKPP-----GDVDSYSITLSHQGTIKESKTLAPPVTETQ 345
Query 579 LSSLTSDTLYMVRM 592
L LY V +
Sbjct 346 FKDLVPGRLYQVTI 359
Score = 87.6 bits (215), Expect = 4e-16, Method: Composition-based stats.
Identities = 78/538 (14%), Positives = 153/538 (28%), Gaps = 54/538 (10%)
Query 78 QYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLS-CIV 136
Q+ II ++ S +F+ + + G + + P+K + +S
Sbjct 687 QFLIIAKSVSECSFSSLTPGRLYNVTVTTKSGNYASHSFTEERTV---PDKVQGISVSNS 743
Query 137 NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV 196
++ W T+K+ F K + C
Sbjct 744 ARSDYLKVSWVHATGDFDHYEVTIKNR---ESFIQTKTIPKSENECEF---IELVPGRLY 797
Query 197 WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK 256
V G+ + + P P +L+++N L +TW S + + +
Sbjct 798 SVTVSTKSGQYEASE---QGTGRTIPEPVKDLTLLNRSTED--LHVTW---SRANGDVDQ 849
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y +Q D P +T + + L P Y + + D S
Sbjct 850 YEVQLLFND---MKVFPHIHLVNTATEYKFTALTPGRHYKILVLTISGD-----VQQSAF 901
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT--LTRWK 374
G+T PS I S + + W G + Y V+ K
Sbjct 902 IEGLTV-------PSTVKNIHISANGATDRLMVTWSP-----GGGDVDSYVVSAFRQDEK 949
Query 375 SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP 434
Q +A++ T + + + ++ G + + + V+ A+
Sbjct 950 VDSQTIPKHASEHTFHRLEAGAKYRIAIVSVSGSLRNQIDALGQTVPASVQGVVAANAY- 1008
Query 435 KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
N L V W + +L + + R + +L K Y +
Sbjct 1009 SSNSLTVSWQ----KALGVAERYDILLLNENGLLLSNVSEPATARQHKFEDLTPGKKYKM 1064
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
+ V + P+ +R + W G + Y
Sbjct 1065 QILTVSGGLFSKESQAEGRT---VPAAVTNLRITENSSRYLSFGW-----TASEGELSWY 1116
Query 555 TIF-YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP 611
IF Y + VD ++ +L +Y + + ++ E + F T P
Sbjct 1117 NIFLYNPDRTLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVP 1174
Score = 84.1 bits (206), Expect = 4e-15, Method: Composition-based stats.
Identities = 94/583 (16%), Positives = 183/583 (31%), Gaps = 79/583 (14%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNV 115
+ N+ I W + + + ++++ + V T++ + + LT G L N+
Sbjct 212 ISPNPNSLLISWSRGSGNVEQYRLVLMDK-GAIVQDTNVDRRDTSYAFHELTPGHLY-NL 269
Query 116 YGITIISGL----------PPEKPKNLSCIVNEG--KKMRCEWDGGRETHLETNFTLKSE 163
+T+ SGL P + NL + N+G + +W + TL +
Sbjct 270 TIVTMASGLQNSRWKLVRTAPMEVSNLK-VTNDGRLTSLNVKWQKPPGDVDSYSITLSHQ 328
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN 223
+ P + T V +V + + G+++++ + P
Sbjct 329 GTIKESKTLAP----PVTETQFKDLVPGRLYQVTISCIS--GELSAEK---SAAGRTVPE 379
Query 224 PPHNLSVINSEELSSILKLTWTNP--SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
NL V +E + WT P + I+ +N S + T
Sbjct 380 KVRNL-VSYNEIWMKSFTVNWTPPAGDWEHYRIVLFN----------ESLVLLNTTVGKE 428
Query 282 -SSFTVQDLK--PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+ + + L+ P +Y + + + SE G T P ++
Sbjct 429 ETHYALDGLELIPGRQYEIEVIVESGNLR-----NSERCQGRTV-------PLAVLQLRV 476
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK----SHLQNYTVNATKLTVNLTND 394
H ++ + W+ G+ Y ++L + + T +
Sbjct 477 KHAN-ETSLGITWRA-----PLGEWEKYIISLMDRELLVIHKSLSKDAKEFTFTDLMPGR 530
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI 454
Y AT+T + K ++ I A + + + L+ WT V+ Y
Sbjct 531 NYKATVTSMSGDLKQSSS---IKGRTVPAQVTDLHVNNQGMTSSLFTNWTKALGDVEFYQ 587
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+ + + + Y L Y + VT V G
Sbjct 588 V-----LLIHENVVVKNESVSSDTSRYSFRALKPGSLYSVVVTTVSG---GISSRQVVAE 639
Query 515 KQAPPSKGPTVRTKKVGKNE-AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSS 573
+ PS V G+N+ + W P G + +Y + + + + S
Sbjct 640 GRTVPSSVSGVTVNNSGRNDYLSVSWLPAP-----GEVDHYVVSLSHEGKVDQFLIIAKS 694
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
+E + SSLT LY V + + T P QG
Sbjct 695 VSECSFSSLTPGRLYNVTVTTKSGNYASHSFTEERTVPDKVQG 737
Score = 81.1 bits (198), Expect = 4e-14, Method: Composition-based stats.
Identities = 72/489 (15%), Positives = 140/489 (29%), Gaps = 110/489 (22%)
Query 236 LSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+ L +W+ S Y + + + +D + + Q L P +Y
Sbjct 1187 TTDSLWFSWSP---ASGDFDFYELILYNPNGTKKENWKEKDV----TEWRFQGLVPGRKY 1239
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
+ G S+ +T E R + +P ++ + WK P
Sbjct 1240 TLYVV----THSGDLSN------KVTGEGRTAPSPPSLLSF---ADVANTSLAITWKGPP 1286
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL---ATLTVRNLVGKS-DA 411
+ D+E+ + ++ K + + +V+ + G S
Sbjct 1287 DWTDYN---DFELQWFPGDALTIFNPYSSRKSEGRIVYGLHPGRSYQFSVKTVSGDSWKT 1343
Query 412 AVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW 470
I + +L P + W P Y +E + + +
Sbjct 1344 YSKPISGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSIECRKMDTQEIEFSRK 1403
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK----QAPPSKGPTVR 526
+++ ++ + L K YL+++ G + PP P +R
Sbjct 1404 LEKEKSLLNIMM---LVPHKRYLVSIKV---QSAGMTSEVVEDSTITMIDRPPQPPPHIR 1457
Query 527 TKK----VGKNEAVL----EW---------------------DQLPVDVQ---------- 547
+ + K+ W D+L + Q
Sbjct 1458 VNEKDVLISKSSINFTVNCSWFSDTNGAVKYFAVVVREADSMDELKPEQQHPLPSYLEYR 1517
Query 548 -NGFIRNYTIFY------RTIIGNETAVNV-------------DSSHTEYTLSSLTSDTL 587
N IR Y Y + + + N+ D S ++ L T
Sbjct 1518 HNASIRVYQTNYFASKCAESPDSSSKSFNIKLGAEMDSLGGKCDPSQQKFCDGPLKPHTA 1577
Query 588 YMVRMAAYTDEGGKDGPEFT--------FTTPKFAQGE-----IEAIVVPVCLAFLLTTL 634
Y + + A+T +D EFT F+ P + E IE + + L +L L
Sbjct 1578 YRISIRAFTQLFDEDLKEFTKPLYSDTFFSMPITTESEPLFGVIEGVSAGLFLIGMLVAL 1637
Query 635 LGVLFCFNK 643
+ C K
Sbjct 1638 VAFFICRQK 1646
Score = 77.2 bits (188), Expect = 7e-13, Method: Composition-based stats.
Identities = 63/525 (12%), Positives = 138/525 (26%), Gaps = 56/525 (11%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
+P ++ + W + + + + ++ T
Sbjct 995 VPASVQGVVAANAYSSNSLTVSWQ--KALGVAERYDILLLNENGLLLSNVSEPAT-ARQH 1051
Query 184 VDYSTVYFVNIEVWV-EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
++ + L S + P NL + +E S L
Sbjct 1052 KFEDLTPGKKYKMQILTVSGGLFSKES-----QAEGRTVPAAVTNLRI--TENSSRYLSF 1104
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
WT + YNI D + + + SF+ Q+L Y ++ +
Sbjct 1105 GWTA---SEGELSWYNIFLYNPDRTLQERAQVDPLV---QSFSFQNLLQGRMY--KMVIV 1156
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
G + S E+ P+ + SH ++ W +
Sbjct 1157 THSG-----ELSNESFIFG-----RTVPAAVNHLKGSHRNTTDSLWFSWSPASGDFDFYE 1206
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
++ Y K + + V + + +Y + D +
Sbjct 1207 LILYN-PNGTKKENWKEKDVTEWRFQGLVPGRKYTLYVVTH----SGDLSNKVTGEGRTA 1261
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESV--KKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ P + A + L + W P + + L+W +T +
Sbjct 1262 PSPPSLLSFADVANTSLAITWKGPPDWTDYNDFELQWFP----GDALTIFNPYSSRKSEG 1317
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
+ L + Y +V V D + + + P K + + W
Sbjct 1318 RIVYGLHPGRSYQFSVKTVSGDSWKTYSKPISGSVRTKPDKIQNLHCRPQNSTAIACSWI 1377
Query 541 QLPVDVQNGFIRNYTIFYRTIIGN--ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
D Y+I R + E + ++ + + L Y+V + +
Sbjct 1378 PPDSDFD-----GYSIECRKMDTQEIEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAG 1432
Query 599 GGKDGPEFTFTT---------PKFAQGEIEAIVVPVCLAFLLTTL 634
+ E + T P E + ++ + F +
Sbjct 1433 MTSEVVEDSTITMIDRPPQPPPHIRVNEKDVLISKSSINFTVNCS 1477
Score = 62.6 bits (150), Expect = 2e-08, Method: Composition-based stats.
Identities = 51/288 (18%), Positives = 93/288 (32%), Gaps = 34/288 (12%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P P LS + W G + +T +++ F P S
Sbjct 1262 PSPPSLLSFADVANTSLAITWKGPPD------WTDYNDFELQWFPGDALTIFNPYSSRKS 1315
Query 186 YSTVYF-----VNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ + + + V+ + K S I+ + KP+ NL + S+
Sbjct 1316 EGRIVYGLHPGRSYQFSVKTVSGDSWKTYSKPIS--GSVRTKPDKIQNLH--CRPQNSTA 1371
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ +W P Y+I+ R D + + + + L P Y+ I
Sbjct 1372 IACSWIPP---DSDFDGYSIECRKMDTQEIEFSRKLEKEKSLLNIMM--LVPHKRYLVSI 1426
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK----IDPSHTQGYRTVQLVWKTLP 355
+ G S+ E+++ IT DRP + P + S + TV W
Sbjct 1427 KVQSA---GMTSEVVEDST-ITMIDRPPQPPPHIRVNEKDVLISKSSINFTVNCSWF--- 1479
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVR 403
+ NG + + V + S + L L R+ A++ V
Sbjct 1480 -SDTNGAVKYFAVVVREADSMDELKPEQQHPLPSYL-EYRHNASIRVY 1525
Score = 41.8 bits (96), Expect = 0.043, Method: Composition-based stats.
Identities = 22/126 (17%), Positives = 39/126 (31%), Gaps = 13/126 (10%)
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
+L Y + + G ++ PP++ V +K
Sbjct 75 NFTYGCNPKDLQAGTVYNFRIVSL----DGEESTLVLQTDPLPPARF-EVNREKTASTTL 129
Query 536 VLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHT--EYTLSSLTSDTLYMVRM 592
+ W +G + Y + + V V S T +YT +LT Y V +
Sbjct 130 QVRWTPS-----SGKVSWYEVQLFDHNNQKIQEVQVQESTTWSQYTFLNLTEGNSYKVAI 184
Query 593 AAYTDE 598
A + E
Sbjct 185 TAVSGE 190
>sp|P19756|GHR_PIG Growth hormone receptor OS=Sus scrofa OX=9823
GN=GHR PE=1 SV=1
Length=638
Score = 99.2 bits (245), Expect = 5e-20, Method: Composition-based stats.
Identities = 44/217 (20%), Positives = 86/217 (40%), Gaps = 26/217 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA-------THKFADCKAK-RDT 178
KPK C E + C W G L++ +++ + T ++ +C
Sbjct 49 GKPKFTKCRSPELETFSCHWTDGVRHGLQSPGSIQLFYIRRSTQEWTQEWKECPDYVSAG 108
Query 179 PTSCTVDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS----VINS 233
SC + S T ++ + + + T D F V+P+PP L+ I+
Sbjct 109 ENSCYFNSSYTSIWIPYCIKLTSNGG----TVDQKCFSVEEIVQPDPPIGLNWTLLNISL 164
Query 234 EELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
+ + +++ W P V I+L+Y +QY+ + + W + P +S V L
Sbjct 165 TGIHADIQVRWEPPPNADVQKGWIVLEYELQYKEVNETQWKMMDPVL----STSVPVYSL 220
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
+ EY R+R + + + + ++SE + P
Sbjct 221 RLDKEYEVRVRSRQRNSE-KYGEFSEVLYVTLPQMSP 256
Score = 63.3 bits (152), Expect = 7e-09, Method: Composition-based stats.
Identities = 82/437 (19%), Positives = 141/437 (32%), Gaps = 68/437 (16%)
Query 447 RESVKKYILEW--CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
R S +++ EW C A + + T Y I +T
Sbjct 88 RRSTQEWTQEWKECPDYVSAGENSCYFNSSYTSIW----------IPYCIKLTSNGGTVD 137
Query 505 GSPESIKAYLKQAPPSKGPTVRTKKVGKN----EAVLEWDQLP-VDVQNG-FIRNYTIFY 558
S++ ++ PP + + + W+ P DVQ G + Y + Y
Sbjct 138 QKCFSVEEIVQPDPPIGL-NWTLLNISLTGIHADIQVRWEPPPNADVQKGWIVLEYELQY 196
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA--YTDEGGKDGPE-FTFTTPKFAQ 615
+ + + + T + SL D Y VR+ + E + E T P+ +
Sbjct 197 KEVNETQWKMMDPVLSTSVPVYSLRLDKEYEVRVRSRQRNSEKYGEFSEVLYVTLPQMSP 256
Query 616 GEIEA-IVVPVCLAFLL----TTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHT 670
E P L + T++ L F+K+ IK I P VP P I P
Sbjct 257 FACEEDFRFPWFLIIIFGIFGLTVILFLLIFSKQQRIKMLILPPVPVP---KIKGIDPDL 313
Query 671 PPRHNF-----------NSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKI 719
N K + YSD ++ + ++I+ D+K D L EK
Sbjct 314 LKEGKLEEVNTILAIHDNYKHEFYSDDSWVEFIELDIDDPDEKTEGSDTDRLLNNDHEKS 373
Query 720 NTEGHSSGIGG----SSCMSSSRPSISSS--DENESSQNTSSTVQYSTVVHSG------Y 767
T +G S S P I + + N+ T+ Q +
Sbjct 374 LT-----ILGAKEDDSGRTSCYEPDILETDFNANDVCDGTAEVAQPQRLKGEADLLCLDQ 428
Query 768 RHQVPSVQVFSRSESTQP--LLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESS 825
++Q S + + QP +L E +P L ++ D Q S S
Sbjct 429 KNQNNSPSNDAAPATQQPSVILAEENKPRPL-IISGTDS------THQTAHTQLSNPSSL 481
Query 826 PDISHFERSKQV-SSVN 841
+I + + + + +
Sbjct 482 ANIDFYAQVSDITPAGS 498
Score = 40.6 bits (93), Expect = 0.068, Method: Composition-based stats.
Identities = 39/272 (14%), Positives = 77/272 (28%), Gaps = 40/272 (15%)
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
W + A + +F+ + P +R + S + E S
Sbjct 4 WQLLLTLAVAGSSDAFSGSEATPAVL----VRASQ----------SLQRVHPGLETNSSG 49
Query 329 APSFWYKIDPSHTQGYRTVQLVWKT--LPPFEANGKILDYEV--TLTRWKSHLQNYTVNA 384
P F + T W ++ G I + + + W +
Sbjct 50 KPKF----TKCRSPELETFSCHWTDGVRHGLQSPGSIQLFYIRRSTQEWTQEWKECPDYV 105
Query 385 T----KLTVNLTNDRYLATLTVR--NLVGKSDAAVLTIPACDFQATHPV------MDLKA 432
+ N + ++ + G D ++ Q P+ +++
Sbjct 106 SAGENSCYFNSSYTSIWIPYCIKLTSNGGTVDQKCFSV-EEIVQPDPPIGLNWTLLNISL 164
Query 433 FPKDNMLWVEWTTPRES--VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
+ V W P + K +I+ L K T W+ D + + +L K
Sbjct 165 TGIHADIQVRWEPPPNADVQKGWIVLEYELQYKEVNETQWKMMDPVLSTSVPVYSLRLDK 224
Query 491 CYLITVTP--VYADGPGS-PESIKAYLKQAPP 519
Y + V ++ G E + L Q P
Sbjct 225 EYEVRVRSRQRNSEKYGEFSEVLYVTLPQMSP 256
>sp|Q60837|I12R1_MOUSE Interleukin-12 receptor subunit beta-1
OS=Mus musculus OX=10090 GN=Il12rb1 PE=1 SV=2
Length=738
Score = 99.5 bits (246), Expect = 5e-20, Method: Composition-based stats.
Identities = 103/592 (17%), Positives = 176/592 (30%), Gaps = 74/592 (13%)
Query 126 PEKPKNLSCIVNEGKKMRCEWD-GGRETHL---------ETNFTLKSEWATHKFADCKAK 175
P P+NLSC C W G E ++ N T + F+ +
Sbjct 45 PLGPRNLSCYRVSKTDYECSWQYDGPEDNVSHVLWCCFVPPNHTHTGQERCRYFSSGPDR 104
Query 176 RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
+ WVE+ + S I+ K PP L I +
Sbjct 105 TVQFWE---QDGIPVLSKVNFWVESRLGNRTMKSQKISQYLYNWTKTTPP--LGHIKVSQ 159
Query 236 LSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD------- 288
L++ W +Q+R + +T + S + D
Sbjct 160 SHRQLRMDWNVSEEAGA-----EVQFRRRMPTTNWTLGDCGPQVNSGSGVLGDIRGSMSE 214
Query 289 --LKP--FTEYVFRIRCMKEDGKG----YWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
L P +IR + G WSDWS + E P + ++P +
Sbjct 215 SCLCPSENMAQEIQIRRRRRLSSGAPGGPWSDWSMPV-CVPPEVLPQA--KIKFLVEPLN 271
Query 341 TQGYRTVQLVWKTLPPFEANG-------KILDYEVTLTRWKSHLQNYTVNATKLT--VNL 391
G R + + ++ G ++ + V + Q T L +NL
Sbjct 272 QGGRRRLTMQGQSPQLAVPEGCRGRPGAQVKKHLVLVRMLSCRCQAQTSKTVPLGKKLNL 331
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK 451
+ Y + + G+S +PA + T L NM ++W +
Sbjct 332 SGATYDLNVLAKTRFGRSTIQKWHLPAQELTET---RALNVSVGGNMTSMQWAA-QAPGT 387
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN-------LAESKCYLITVTP------ 498
Y LEW + + L + +CY ITV
Sbjct 388 TYCLEWQPWFQHRNHTHCTLIVPEEEDPAKMVTHSWSSKPTLEQEECYRITVFASKNPKN 447
Query 499 -VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
+ S +A V + + +EW + G + Y +
Sbjct 448 PMLWATVLSSYYFGGNASRA--GTPRHVSVRNQTGDSVSVEWTASQLSTCPGVLTQYVVR 505
Query 558 YRTIIGNETAVN-VDSSHTEYTLSSLTSDTLYMVRMAAYTDE--GGKDGPEFTFTTPKFA 614
G + V + T+ TL L S +Y V++ A T G P+ + +
Sbjct 506 CEAEDGAWESEWLVPPTKTQVTLDGLRSRVMYKVQVRADTARLPGAWSHPQRFSFEVQIS 565
Query 615 QGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQW 666
+ I + + LL LG N+ H+ P +P P S ++
Sbjct 566 RLSIIFASLGSFASVLLVGSLG-YIGLNRAAW---HLCPPLPTPCGSTAVEF 613
>sp|Q06805|TIE1_BOVIN Tyrosine-protein kinase receptor Tie-1 OS=Bos
taurus OX=9913 GN=TIE1 PE=2 SV=1
Length=1136
Score = 99 bits (247), Expect = 5e-20, Method: Composition-based stats.
Identities = 65/310 (21%), Positives = 103/310 (33%), Gaps = 32/310 (10%)
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS-T 268
D F KV P P ++ S L ++ I + YR +D++
Sbjct 433 DSRRFRINVKVPPVPLTAPRLLAK--QSRQLVVSPLVSFSGDGPIASVRLHYRPQDSTMA 490
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
WS I + T+ +L+P T Y R++ + G+G W T D P
Sbjct 491 WSTI----VVDPSENVTLMNLRPKTGYSVRVQ-LSRPGEGGEGAWGPPTLMTT--DCPEP 543
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS-------HLQNYT 381
W ++ H +G +++ W +LPP G ++ L W +
Sbjct 544 LLKPW--LEGWHVEGPDRLRVSW-SLPPVP--GPLVGDGFLLRLWDGARGQERRENVSSP 598
Query 382 VNATKLTVNLTNDRYL---ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
T L LT Y L L+G + A + + +A D+
Sbjct 599 QARTALLTGLTPGTYYQLDVRLYHCTLLGPASPAARVLLPPSGPPAPRHLHAQAL-SDSE 657
Query 439 LWVEWTTP---RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLIT 495
+ + W P + KYI+E V W D + + L S YL
Sbjct 658 IQLMWQRPEAAAGPISKYIVE--VQVAGGSGDPLWMDVDRPEETSTIVRGLNASTRYLFR 715
Query 496 VTPVYADGPG 505
V GPG
Sbjct 716 VRA-SVQGPG 724
Score = 93.0 bits (229), Expect = 8e-18, Method: Composition-based stats.
Identities = 64/410 (16%), Positives = 113/410 (28%), Gaps = 52/410 (13%)
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH--LQNYTV 382
P AP K R + + L F +G I + S V
Sbjct 446 VPLTAPRLLAK-------QSRQLVVS--PLVSFSGDGPIASVRLHYRPQDSTMAWSTIVV 496
Query 383 NATKLTVN---LTNDRYLATLT-VRNLVG----KSDAAVLTIPACDFQATHPVMDLKAFP 434
+ ++ Y + R G ++T C P ++
Sbjct 497 DPSENVTLMNLRPKTGYSVRVQLSRPGEGGEGAWGPPTLMT-TDCPEPLLKPWLEGWHVE 555
Query 435 KDNMLWVEWTTPRESVKKYILEWC---VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
+ L V W+ P V ++ L D A + RT L L
Sbjct 556 GPDRLRVSWSLPP--VPGPLVGDGFLLRLWDGARGQERRENVSSPQARTALLTGLTPGTY 613
Query 492 YLI--TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
Y + + GP SP + L + P + + + +E L W + G
Sbjct 614 YQLDVRLYHCTLLGPASPA-ARVLLPPSGPPAPRHLHAQALSDSEIQLMWQ--RPEAAAG 670
Query 550 FIRNYTIFYRTIIGNETAVNVD---SSHTEYTLSSLTSDTLYMVRMAAYTDEGGK----- 601
I Y + + G+ + +D T + L + T Y+ R+ A G
Sbjct 671 PISKYIVEVQVAGGSGDPLWMDVDRPEETSTIVRGLNASTRYLFRVRASVQGPGDWSNVV 730
Query 602 -----------DGPEFTFTTPKFAQGEIEAIVVPVCLAFLL---TTLLGVLFCFNKRDLI 647
+GP + + + V ++ L L C K L
Sbjct 731 EQSTLGNGLQIEGPVQEIHAAEEGLDQQLVLAVVGSVSATCLTILAALLTLACIRKSCLH 790
Query 648 KKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIE 697
++ + + I Q+S T + + + E
Sbjct 791 RRRTFTYQSGSGEETILQFSSGTLTLTRRPKPQPEPLNYPVLEWEDITFE 840
Score = 68.0 bits (164), Expect = 3e-10, Method: Composition-based stats.
Identities = 35/184 (19%), Positives = 64/184 (35%), Gaps = 16/184 (9%)
Query 142 MRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRDTP---TSCTVDYSTVYFVNIEVW 197
+R W L + L W + + + +P T+ + + ++V
Sbjct 560 LRVSWSLPPVPGPLVGDGFLLRLWDGARGQERRENVSSPQARTALLTGLTPGTYYQLDVR 619
Query 198 VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY 257
+ LG + P PP + S ++L W P + I KY
Sbjct 620 LYHCTLLGPASPAARVLLP----PSGPPAPRHLHAQALSDSEIQLMWQRPEAAAGPISKY 675
Query 258 NIQYRTKDAST---WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
++ + S W + +S V+ L T Y+FR+R G G WS+
Sbjct 676 IVEVQVAGGSGDPLWMDVDR----PEETSTIVRGLNASTRYLFRVRAS-VQGPGDWSNVV 730
Query 315 EEAS 318
E+++
Sbjct 731 EQST 734
Score = 57.9 bits (138), Expect = 4e-07, Method: Composition-based stats.
Identities = 33/210 (16%), Positives = 67/210 (32%), Gaps = 22/210 (10%)
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
L+++W+ P + ++ R D + + ++ + + L P T Y
Sbjct 557 PDRLRVSWSLPPVP-GPLVGDGFLLRLWDGARGQERRENVSSPQARTALLTGLTPGTYYQ 615
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
+R S A + P P + + +QL+W+ P
Sbjct 616 LDVRLY---HCTLLGPASPAARVL----LPPSGPPAPRHLH-AQALSDSEIQLMWQ--RP 665
Query 357 FEANGKILDYEVTLT-------RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
A G I Y V + + +T + + RYL + ++ G
Sbjct 666 EAAAGPISKYIVEVQVAGGSGDPLWMDVDRPEETSTIVRGLNASTRYLFRVRA-SVQGPG 724
Query 410 DAAVLTIPAC---DFQATHPVMDLKAFPKD 436
D + + + Q PV ++ A +
Sbjct 725 DWSNVVEQSTLGNGLQIEGPVQEIHAAEEG 754
>sp|P34902|IL2RG_MOUSE Cytokine receptor common subunit gamma
OS=Mus musculus OX=10090 GN=Il2rg PE=1 SV=1
Length=369
Score = 96.5 bits (238), Expect = 5e-20, Method: Composition-based stats.
Identities = 48/209 (23%), Positives = 82/209 (39%), Gaps = 22/209 (11%)
Query 131 NLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATH---KFADCKA---KRDTPTSCTV 184
+ C V + M C W+ E TN TL + F +C ++ + C +
Sbjct 59 EVQCFVFNIEYMNCTWNSSSEPQ-ATNLTLHYRYKVSDNNTFQECSHYLFSKEITSGCQI 117
Query 185 DYSTV-YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
+ + V ++ + +N + V P P NL++ N E S L+L
Sbjct 118 QKEDIQLYQTFVVQLQDPQKPQRRAVQKLNLQNL--VIPRAPENLTLSNLSE--SQLELR 173
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
W + IK L+Y +QYR+ +W+++ + F++ + Y FR+R
Sbjct 174 WKSRHIKERC-LQYLVQYRSNRDRSWTEL----IVNHEPRFSLPSVDELKRYTFRVRSRY 228
Query 304 EDGKG---YWSDWSEEAS--GITYEDRPS 327
G WS WS+ T E+ PS
Sbjct 229 NPICGSSQQWSKWSQPVHWGSHTVEENPS 257
Score = 43.7 bits (101), Expect = 0.006, Method: Composition-based stats.
Identities = 22/137 (16%), Positives = 50/137 (36%), Gaps = 15/137 (11%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
P + + +++ L W + + Y + YR+ + + ++
Sbjct 154 PRAPENLTLSNLSESQLELRWKSRHIKER---CLQYLVQYRSNRDRSWTELIVNHEPRFS 210
Query 579 LSSLTSDTLYMVRMAA-YTDEGGKDGPEFTFTTPKFAQGE----------IEAIVVPVCL 627
L S+ Y R+ + Y G ++ P +EA+++PV
Sbjct 211 LPSVDELKRYTFRVRSRYNPICGSSQQWSKWSQPVHWGSHTVEENPSLFALEAVLIPVGT 270
Query 628 AFLLTTLLGVLFCFNKR 644
L+ TL+ ++C+ +R
Sbjct 271 MGLIITLI-FVYCWLER 286
Score = 36.4 bits (82), Expect = 1.2, Method: Composition-based stats.
Identities = 25/199 (13%), Positives = 55/199 (28%), Gaps = 15/199 (8%)
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ----NYTVN 383
AP+ + W + +A L Y ++ + + ++
Sbjct 51 SAPTLPLPEVQCFVFNIEYMNCTWNSSSEPQATNLTLHYRYKVSDNNTFQECSHYLFSKE 110
Query 384 ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ----ATHPVMDLKAFPKDNML 439
T D L V L + + Q P + ++ L
Sbjct 111 ITSGCQIQKEDIQLYQTFVVQLQDPQKPQRRAVQKLNLQNLVIPRAPENLTLSNLSESQL 170
Query 440 WVEWT--TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
+ W +E +Y++++ + W + + ++ E K Y V
Sbjct 171 ELRWKSRHIKERCLQYLVQYR-----SNRDRSWTELIVNHEPRFSLPSVDELKRYTFRVR 225
Query 498 PVYADGPGSPESIKAYLKQ 516
Y GS + + +
Sbjct 226 SRYNPICGSSQQWSKWSQP 244
>sp|P16144|ITB4_HUMAN Integrin beta-4 OS=Homo sapiens OX=9606
GN=ITGB4 PE=1 SV=5
Length=1822
Score = 99.5 bits (246), Expect = 9e-20, Method: Composition-based stats.
Identities = 75/548 (14%), Positives = 157/548 (29%), Gaps = 56/548 (10%)
Query 120 IISGLPP-----EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA 174
++S PP P+N + +K+ W + + +K W
Sbjct 1116 MLSSQPPPHGDLGAPQNPNAKAAGSRKIHFNWLP--PSGKPMGYRVKY-WIQGDSESEAH 1172
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
D+ + + + E+ V A A G+ + ++ P+ P L+ +
Sbjct 1173 LLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLA--FNV 1230
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT---ASTRSSFTVQDLKP 291
S++ +L+W P+ + I Y + Y + P + +++L+
Sbjct 1231 VSSTVTQLSWAEPAETNGEITAYEVCYGLVNDDNRPIGPMKKVLVDNPKNRMLLIENLRE 1290
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGI----TYEDRPSKAPSFWYKIDPSHTQGYRTV 347
Y + ++ G W E I T RP P G
Sbjct 1291 SQPYRYTVKARNGAG------WGPEREAIINLATQPKRPMSIPIIPDIPIVDAQSGEDYD 1344
Query 348 Q-LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLV 406
L++ +G T + + +L + R L R
Sbjct 1345 SFLMYSDDVLRSPSGSQRPSVSDDTGC--GWKFEPLLGEELDLRRVTWRLPPELIPRLSA 1402
Query 407 GKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
++ P + P+ P E + ++
Sbjct 1403 SSGRSSDAEAPHGPPDDGGAGGKGGSLPRS----ATPGPPGEHLVNGRMD-FAFPGSTNS 1457
Query 467 ITDWQQEDGTVHRTYLRGN------------------LAESKCYLITVTPVYADGPGSPE 508
+ + T+L + L S+ T P S
Sbjct 1458 LHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVS 1517
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV 568
S + L P + +G + W + + ++ Y++ Y+ + G E
Sbjct 1518 SHDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERP---LQGYSVEYQLLNGGELHR 1574
Query 569 N--VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVC 626
+ + T + L + Y+ R+ A + EG G E +Q ++ + P+
Sbjct 1575 LNIPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGW--GREREGVITIESQVHPQSPLCPLP 1632
Query 627 LAFLLTTL 634
+ +
Sbjct 1633 GSAFTLST 1640
Score = 97.2 bits (240), Expect = 4e-19, Method: Composition-based stats.
Identities = 50/278 (18%), Positives = 81/278 (29%), Gaps = 52/278 (19%)
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA 423
DY SH + + LT ++D LT
Sbjct 1490 RDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDS---RLTAGV------------------P 1528
Query 424 THPVMDLKAFPKDNMLWVEWTTPR--ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
P + + L V W PR ++ Y +E+ +L+ +
Sbjct 1529 DTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGE---LHRLNIPNPAQTSV 1585
Query 482 LRGNLAESKCYLITVTPVYADGPG-------------------SPESIKAYLKQAPPSKG 522
+ +L + Y+ V +G G P A+ P + G
Sbjct 1586 VVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPG 1645
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI--FYRTIIGNETAVNVD--SSHTEYT 578
P + + + L W+ NG I Y + G TA VD S + T
Sbjct 1646 P-LVFTALSPDSLQLSWE--RPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLT 1702
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
+ L+ + Y ++ A T EG E T G
Sbjct 1703 VPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGG 1740
Score = 87.2 bits (214), Expect = 5e-16, Method: Composition-based stats.
Identities = 55/305 (18%), Positives = 102/305 (33%), Gaps = 40/305 (13%)
Query 148 GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV--DYSTVYFVNIEVWVEAENALG 205
G L T + + R TS T+ DY+++
Sbjct 1452 PGSTNSLHRMTTTSAAAYGTHLSPHVPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYS 1511
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD 265
+TS + + P+ P L + L+++W P + + Y+++Y+ +
Sbjct 1512 TLTSVSSHDSRLTAGVPDTPTRLVFSALG--PTSLRVSWQEPRCER-PLQGYSVEYQLLN 1568
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG--------------YWS 311
++ + ++S V+DL P YVFR+R ++G G S
Sbjct 1569 GGELHRLNIPN--PAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQS 1626
Query 312 DWSE-EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S T + P + + P ++QL W+ P NG I+ Y VT
Sbjct 1627 PLCPLPGSAFTLSTPSAPGPLVFTALSPD------SLQLSWE--RPRRPNGDIVGYLVTC 1678
Query 371 TRWKSHLQ------NYTVNATKLTVNLTND--RYLATLTVRNLVGKSD--AAVLTIPACD 420
+ + ++LTV ++ Y + R G ++TI + D
Sbjct 1679 EMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQD 1738
Query 421 FQATH 425
Sbjct 1739 GGPFP 1743
Score = 74.9 bits (182), Expect = 3e-12, Method: Composition-based stats.
Identities = 47/217 (22%), Positives = 75/217 (35%), Gaps = 29/217 (13%)
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD 265
TS ++ P P N + + S + W PS + Y ++Y +
Sbjct 1111 SFTSQMLSSQPPPHGDLGAPQNPNAKAAG--SRKIHFNWLPPS---GKPMGYRVKYWIQG 1165
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
S+ S S + +L P+ +Y ++ G+G +S S T+++
Sbjct 1166 D---SESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSS---LVSCRTHQEV 1219
Query 326 PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV----------TLTRWKS 375
PS+ + + S QL W P E NG+I YEV + K
Sbjct 1220 PSEPGRLAFNVVSSTVT-----QLSWAE--PAETNGEITAYEVCYGLVNDDNRPIGPMKK 1272
Query 376 HLQNYTVNATKLTVNLTN-DRYLATLTVRNLVGKSDA 411
L + N L NL Y T+ RN G
Sbjct 1273 VLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPE 1309
Score = 74.5 bits (181), Expect = 4e-12, Method: Composition-based stats.
Identities = 39/272 (14%), Positives = 77/272 (28%), Gaps = 23/272 (8%)
Query 74 IPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLS 133
+P + + + + T + + + +G+ P+ P L
Sbjct 1477 VPHRVLSTSSTLTRDYNSLTRSEHSHSTTLPRDYSTLTSVSSHDSRLTAGV-PDTPTRLV 1535
Query 134 CIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY-FV 192
+R W R ++++ + + P +V +
Sbjct 1536 FSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGG-ELHRLNIPNPAQTSVVVEDLLPNH 1594
Query 193 NIEVWVEAENALGKVTSDHINFDPVYKVKPNPP--------HNLS-------VINSEELS 237
+ V A++ G +V P P LS ++ +
Sbjct 1595 SYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSP 1654
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
L+L+W P + I+ Y + + D S S TV L Y F
Sbjct 1655 DSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDSPESRLTVPGLSENVPYKF 1714
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
+++ +G G E IT E +
Sbjct 1715 KVQARTTEGFGP-----EREGIITIESQDGGP 1741
>sp|Q2Q0I9|FNDC1_RAT Fibronectin type III domain-containing protein
1 OS=Rattus norvegicus OX=10116 GN=Fndc1 PE=1 SV=2
Length=1779
Score = 99.2 bits (245), Expect = 1e-19, Method: Composition-based stats.
Identities = 57/423 (13%), Positives = 123/423 (29%), Gaps = 68/423 (16%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
P P ++ ++++ LK+TW P + ++ Y + +
Sbjct 34 VDHPLKPRHVKLLSANMG---LKVTWDPPKDATSRPVE---HYNIAYGKSLKSLKSIKVN 87
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+ SF ++D++ + P+K +
Sbjct 88 AETHSFLIKDVEK--------------------------------EVPNKPLRMRVRASD 115
Query 339 SHTQGYRTVQLVWKTL------PPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT 392
+ + WK P + G +L Y + + + ++ +
Sbjct 116 DR------LSVAWKAPRLSGAKSPRRSRGFLLGYGESGRKMNYVPLTRDERSHEIKKLAS 169
Query 393 NDRYLATLTVRNLVGKSDA----AVLTIPACDFQATHPVMDLKAFPKDN-MLWVEWTTPR 447
Y+ +L N G+S A+ + D+ + + V W P
Sbjct 170 ESVYVVSLQSTNSQGQSQPVYRAALTKRKNAEEDELDVPEDISVRVMSSQSVLVAWVDPL 229
Query 448 ESVKKYIL---EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
+K ++ ++ V + W + + R L +L Y V +
Sbjct 230 VEKQKRVVASRQYTVRYREKGESARWDYKQVSNRRA-LVDSLIPDTVYEFAVRISQGERD 288
Query 505 GS-PESIKAYLKQAPPSKGP-TVRTKKV--GKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G S+ ++ P+ P +R V + WD LP G ++ Y + Y
Sbjct 289 GKWSASVFQRTPESAPTTAPENLRVWPVNGKPTVVTVSWDALPESE--GKVKEYILSYAP 346
Query 561 IIGN--ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT-TPKFAQGE 617
+ ++ T + L Y+ ++ A G + P + E
Sbjct 347 ALKPFGAKSLTFSGHTTSALVDGLQPGERYLFKIRATNRRGQGPHSKAFIVAIPTTSSTE 406
Query 618 IEA 620
Sbjct 407 ASV 409
Score = 85.7 bits (210), Expect = 2e-15, Method: Composition-based stats.
Identities = 61/318 (19%), Positives = 104/318 (33%), Gaps = 35/318 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLET-----NFTLKSEWATHKFADCKAKRDTP 179
P KP + ++ + + W R + ++ F L + K RD
Sbjct 102 VPNKPLRMRVRASDDR-LSVAWKAPRLSGAKSPRRSRGFLLGYGESGRKMNYVPLTRD-- 158
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVK------PNPPHNLSVINS 233
V +++ N+ G+ S + + K K + P ++SV
Sbjct 159 ERSHEIKKLASESVYVVSLQSTNSQGQ--SQPVYRAALTKRKNAEEDELDVPEDISV--R 214
Query 234 EELSSILKLTWTNP----SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
S + + W +P + V +Y ++YR K S + V L
Sbjct 215 VMSSQSVLVAWVDPLVEKQKRVVASRQYTVRYREKGESARWDYKQV----SNRRALVDSL 270
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
P T Y F +R + + G WS T E P+ AP V +
Sbjct 271 IPDTVYEFAVRISQGERDG---KWSASVFQRTPESAPTTAPENLRVWPV--NGKPTVVTV 325
Query 350 VWKTLPPFEA--NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT--NDRYLATLTVRNL 405
W LP E IL Y L + + ++ + T V+ +RYL + N
Sbjct 326 SWDALPESEGKVKEYILSYAPALKPFGAKSLTFSGHTTSALVDGLQPGERYLFKIRATNR 385
Query 406 VGKSDAAVLTIPACDFQA 423
G+ + I A +
Sbjct 386 RGQGPHSKAFIVAIPTTS 403
Score = 74.9 bits (182), Expect = 3e-12, Method: Composition-based stats.
Identities = 35/225 (16%), Positives = 65/225 (29%), Gaps = 8/225 (4%)
Query 127 EKPKNLSCIVNEGKKMRCEW-DGGRETH----LETNFTLKSEWATHKFADCKAKRDTPTS 181
+ P+++S V + + W D E +T++ + +
Sbjct 206 DVPEDISVRVMSSQSVLVAWVDPLVEKQKRVVASRQYTVRYREKGESARWDYKQVSNRRA 265
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
V + GK ++ P P NL V +++
Sbjct 266 LVDSLIPDTVYEFAVRISQGERDGKWSASVFQRTPES-APTTAPENLRVWPVNGKPTVVT 324
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
++W + +Y + Y + +S V L+P Y+F+IR
Sbjct 325 VSWDALPESEGKVKEYILSYAPALKP--FGAKSLTFSGHTTSALVDGLQPGERYLFKIRA 382
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
G+G S A T S P+ P Q +
Sbjct 383 TNRRGQGPHSKAFIVAIPTTSSTEASVQPNGRDNGKPEKPQQPSS 427
Score = 59.5 bits (142), Expect = 2e-07, Method: Composition-based stats.
Identities = 41/214 (19%), Positives = 70/214 (33%), Gaps = 32/214 (15%)
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVI 231
+D C++ + +F + N L K + P N++V+
Sbjct 1501 TYLSKDPAAPCSLTDALDHFQVESLDELIPNDLTKNDLPPQH----------APRNITVV 1550
Query 232 NSEELSSILKLTWTNPSIKSVII--LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
E S + + W V+ L Y+ Y + WS S+ + +++L
Sbjct 1551 AMEGCHSFVIVDWNKAIPGDVVTGYLVYSASYEDFIRNKWSTQ-----TSSVTHLPIENL 1605
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED------RPSKAPSFWYKIDPSHT-- 341
KP T Y F+++ G G S S +T D RP W H
Sbjct 1606 KPNTRYYFKVQAKNPHGYG---PVSPSVSFVTESDNPLLVVRPPGGEPIWIPFAFKHDPG 1662
Query 342 ----QGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
G + V+ W L Y++ L+
Sbjct 1663 YTDCHGRQYVKRTWYKKFVGVVLCNSLRYKIYLS 1696
Score = 49.5 bits (116), Expect = 2e-04, Method: Composition-based stats.
Identities = 21/135 (16%), Positives = 41/135 (30%), Gaps = 14/135 (10%)
Query 420 DFQATHPVMDLKAFPKD---NMLWVEWTT--PRESVKKYILEWCVLSDKAPCITDWQQED 474
D H ++ + + + V+W P + V Y++ S + W +
Sbjct 1537 DLPPQHAPRNITVVAMEGCHSFVIVDWNKAIPGDVVTGYLVY--SASYEDFIRNKWSTQT 1594
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE 534
+V + NL + Y V G G +++ + S P + + G
Sbjct 1595 SSVTHLPI-ENLKPNTRYYFKVQAKNPHGYGPVSPSVSFVTE---SDNPLLVVRPPGGEP 1650
Query 535 AVLEWDQLPVDVQNG 549
W G
Sbjct 1651 I---WIPFAFKHDPG 1662
Score = 44.8 bits (104), Expect = 0.005, Method: Composition-based stats.
Identities = 25/151 (17%), Positives = 51/151 (34%), Gaps = 14/151 (9%)
Query 513 YLKQAPPSKGP-TVRTKKVGK--NEAVLEWDQLPVDVQNGFIRNYTIF---YRTIIGNET 566
PP P + + + +++W+ + + Y ++ Y I N+
Sbjct 1534 TKNDLPPQHAPRNITVVAMEGCHSFVIVDWN---KAIPGDVVTGYLVYSASYEDFIRNKW 1590
Query 567 AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAI--VV 623
+ SS T + +L +T Y ++ A G P +F T +
Sbjct 1591 STQ-TSSVTHLPIENLKPNTRYYFKVQAKNPHGYGPVSPSVSFVTESDNPLLVVRPPGGE 1649
Query 624 PVCLAFLLTTLLGVLFCFNKRDLIKKHIWPN 654
P+ + F G C + R +K+ +
Sbjct 1650 PIWIPFAFKHDPGYTDC-HGRQYVKRTWYKK 1679
>sp|Q95JF2|GHR_AILME Growth hormone receptor OS=Ailuropoda melanoleuca
OX=9646 GN=GHR PE=2 SV=1
Length=638
Score = 97.2 bits (240), Expect = 2e-19, Method: Composition-based stats.
Identities = 44/207 (21%), Positives = 80/207 (39%), Gaps = 27/207 (13%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGR------ETHLETNFTLKSEWA-THKFADCKAK-R 176
P KP+ C E + C W G ++ + +S T ++ +C
Sbjct 47 PSGKPQFTKCRSPELETFSCHWTEGVHHGVKNPGSIQLFYIRRSTQEWTPEWKECPDYVS 106
Query 177 DTPTSCTVDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS----VI 231
SC + S T ++ + + + T D F V+P+PP L+ I
Sbjct 107 AGENSCYFNSSYTSIWIPYCIKLTSNGD----TVDQKCFSVEEIVQPDPPIGLNWTLLNI 162
Query 232 NSEELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
+ + + +++ W P V I+L+Y +QY+ + S W + P +S V
Sbjct 163 SLTGIHADIQVRWEPPPNADVQKGWIVLEYELQYKEVNESQWKMMDPVL----STSVPVY 218
Query 288 DLKPFTEYVFRIRC--MKEDGKGYWSD 312
L+ EY R+R + G +S+
Sbjct 219 SLRLDKEYEVRVRSRQRNSEKYGEFSE 245
Score = 59.5 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 75/379 (20%), Positives = 128/379 (34%), Gaps = 48/379 (13%)
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
EW + P + + +Y + Y I +T S++ +
Sbjct 92 QEWTPEWKECPDYVSAGENSCYFNSSYTSIWI----PYCIKLTSNGDTVDQKCFSVEEIV 147
Query 515 KQAPPSKGPTVRTKKVGKN----EAVLEWDQLP-VDVQNG-FIRNYTIFYRTIIGNETAV 568
+ PP + + + W+ P DVQ G + Y + Y+ + ++ +
Sbjct 148 QPDPPIGL-NWTLLNISLTGIHADIQVRWEPPPNADVQKGWIVLEYELQYKEVNESQWKM 206
Query 569 NVDSSHTEYTLSSLTSDTLYMVRMAA--YTDEGGKDGPE-FTFTTPKFAQGEIEA-IVVP 624
T + SL D Y VR+ + E + E P+ + E P
Sbjct 207 MDPVLSTSVPVYSLRLDKEYEVRVRSRQRNSEKYGEFSEVLYVALPQMSPFACEEDFQFP 266
Query 625 VCLAFLL----TTLLGVLFCFNKRDLIKKHIWPNVPDPS---------KSHIAQWSPHTP 671
L + T++ LF F+K+ IK I P VP P K +
Sbjct 267 WFLIIIFGIFGLTMILFLFIFSKQQRIKMLILPPVPVPKIKGIDSDLLKEGKLEEVSTIL 326
Query 672 PRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGG- 730
H+ N K + Y+D ++ + ++I+ D+K D L EK + +G
Sbjct 327 AIHD-NYKPEFYNDDSWVEFIELDIDDPDEKTEGSDTDRLLSNDHEK-----SLNILGAK 380
Query 731 ---SSCMSSSRPSISSSDENESS--QNTSSTVQYSTVVHS------GYRHQVPSVQVFSR 779
S S P I +D N S TS Q + ++Q S +
Sbjct 381 DDDSGRTSCYEPDILETDFNASDVCDGTSEVAQPQRLKGEIDLLCLDQKNQSNSPSTDTA 440
Query 780 SESTQP--LLDSEERPEDL 796
+ QP +L E +P L
Sbjct 441 PNTQQPGVILAKENKPRPL 459
Score = 41.4 bits (95), Expect = 0.044, Method: Composition-based stats.
Identities = 27/204 (13%), Positives = 51/204 (25%), Gaps = 19/204 (9%)
Query 326 PSKAPSFWYKIDPSHTQGYRTVQLVWK-------TLPPFEANGKILDYEVTLTRWKSHLQ 378
P PS + + T W P I T
Sbjct 43 PGTNPSGKPQFTKCRSPELETFSCHWTEGVHHGVKNPGSIQLFYIRRSTQEWTPEWKECP 102
Query 379 NYTVNA-TKLTVNLTNDRYLATLTVR-NLVGKSDAAVLTIPACDFQATHPV------MDL 430
+Y N + ++ G + Q P+ +++
Sbjct 103 DYVSAGENSCYFNSSYTSIWIPYCIKLTSNGDTVDQKCFSVEEIVQPDPPIGLNWTLLNI 162
Query 431 KAFPKDNMLWVEWTTPRES--VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
+ V W P + K +I+ L K + W+ D + + +L
Sbjct 163 SLTGIHADIQVRWEPPPNADVQKGWIVLEYELQYKEVNESQWKMMDPVLSTSVPVYSLRL 222
Query 489 SKCYLITVTP--VYADGPGSPESI 510
K Y + V ++ G +
Sbjct 223 DKEYEVRVRSRQRNSEKYGEFSEV 246
>sp|O35158|CDON_RAT Cell adhesion molecule-related/down-regulated
by oncogenes OS=Rattus norvegicus OX=10116 GN=Cdon PE=1
SV=2
Length=1256
Score = 98.0 bits (242), Expect = 2e-19, Method: Composition-based stats.
Identities = 63/399 (16%), Positives = 119/399 (30%), Gaps = 69/399 (17%)
Query 117 GITIISGL---PPEKPKNLSC-IVNEGKKMRCEWDGGRETHLETN-FTLKSEW--ATHKF 169
G+ + + P+ P LS + W GR+ + N + +K
Sbjct 562 GVELPAEKNASVPDAPNILSPPQTHMPDTYTLVWRTGRDGGMPINAYFVKYRKLDDGSGA 621
Query 170 ADCKAKRDTPTSCTVDYSTVYFVN--IEVWVEAENALG-----------------KVTSD 210
P S + + T + EV + A +A+G +
Sbjct 622 VGSWHTVRVPGSESELHLTELEPSSLYEVLMVARSAVGEGQPAMLTFRTSKEKMASSKNT 681
Query 211 HINFDPVYKVK-------------------------PNPPHNLSVINSEELSSILKLTWT 245
+F PV K P P ++ + E S + +TW
Sbjct 682 QASFPPVGIPKRPVTSEASNSNFGVVLTDSSRHSGVPEAPDRPTISMASETS--VYVTWI 739
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
+ I + ++Y+ +S W + ED ++ S V+ L+P + Y FR+ +
Sbjct 740 PRANGGSPITAFKVEYKRMKSSDW-LVAAEDIPPSKLSVEVRSLEPGSIYKFRVIVINHY 798
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G+ + S S + +R S P I + + L W +P N I
Sbjct 799 GESFRSSASRPYQVAGFPNRFSNRPITGPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQG 858
Query 366 YEVTLTRWKSHL----QNYTVNATK----LTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
+ + S + V +K + Y + N G+S+ + + I
Sbjct 859 FYIYYRPTDSDNDSDYKRDVVEGSKQWHTIGHLQPETSYDIKMQCFNEGGESEFSNVMIC 918
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
+ + P S +
Sbjct 919 ETKVKRVPGASEYPMKELST-------PPSSSGNGGNVG 950
Score = 89.5 bits (220), Expect = 8e-17, Method: Composition-based stats.
Identities = 64/419 (15%), Positives = 116/419 (28%), Gaps = 108/419 (26%)
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT---- 385
P + P T T LVW+T + I Y V + T
Sbjct 574 PDAPNILSPPQTHMPDTYTLVWRT--GRDGGMPINAYFVKYRKLDDGSGAVGSWHTVRVP 631
Query 386 ------KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ----------------- 422
LT + Y + R+ VG+ A+LT +
Sbjct 632 GSESELHLTELEPSSLYEVLMVARSAVGEGQPAMLTFRTSKEKMASSKNTQASFPPVGIP 691
Query 423 --------------------------ATHPVMDLKAFPKDNMLWVEWTT---PRESVKKY 453
P + + ++V W + +
Sbjct 692 KRPVTSEASNSNFGVVLTDSSRHSGVPEAPDRPTISMASETSVYVTWIPRANGGSPITAF 751
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG------SP 507
+E+ + + + + +R L Y V + G P
Sbjct 752 KVEYKRMKSSD-WLVAAEDIPPSKLSVEVRS-LEPGSIYKFRVIVINHYGESFRSSASRP 809
Query 508 ESIKAYLKQ--APPSKGPTVR-TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN 564
+ + + P GP + T+ V + +L+W +P N I+ + I+YR +
Sbjct 810 YQVAGFPNRFSNRPITGPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSD 869
Query 565 ETA----VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG---------------GKDG-- 603
+ V+ S +T+ L +T Y ++M + + G G
Sbjct 870 NDSDYKRDVVEGSKQWHTIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGAS 929
Query 604 --PEFTFTTPKFAQG----------------EIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
P +TP + G + IV V +L L+ + C K
Sbjct 930 EYPMKELSTPPSSSGNGGNVGPATSPARSSDMLYLIVGCVLGVMVLILLVFIALCLWKS 988
Score = 60.3 bits (144), Expect = 8e-08, Method: Composition-based stats.
Identities = 26/242 (11%), Positives = 57/242 (24%), Gaps = 52/242 (21%)
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE---SVKKYILEWCVLSDKA 464
+ ++ + + W T R+ + Y +++ L D +
Sbjct 560 SGGVELPAEKNASVPDAPNILSPPQTHMPDTYTLVWRTGRDGGMPINAYFVKYRKLDDGS 619
Query 465 PCITDWQQE-DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ------- 516
+ W L S Y + + A G G P + +
Sbjct 620 GAVGSWHTVRVPGSESELHLTELEPSSLYEVLMVARSAVGEGQPAMLTFRTSKEKMASSK 679
Query 517 ------------------------------------APPSKGPTVRTKKVGKNEAVLEWD 540
P + + W
Sbjct 680 NTQASFPPVGIPKRPVTSEASNSNFGVVLTDSSRHSGVPEAPDRPTISMASETSVYVTW- 738
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
+P I + + Y+ + ++ A ++ S + SL ++Y R+
Sbjct 739 -IPRANGGSPITAFKVEYKRMKSSDWLVAAEDIPPSKLSVEVRSLEPGSIYKFRVIVINH 797
Query 598 EG 599
G
Sbjct 798 YG 799
Score = 44.5 bits (103), Expect = 0.006, Method: Composition-based stats.
Identities = 30/119 (25%), Positives = 41/119 (34%), Gaps = 13/119 (11%)
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG-FIRNYTIF 557
V++ G P A + AP P + L W G I Y +
Sbjct 558 VHSGGVELPAEKNASVPDAPNILSPPQTHM---PDTYTLVWR---TGRDGGMPINAYFVK 611
Query 558 YRTII------GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
YR + G+ V V S +E L+ L +LY V M A + G TF T
Sbjct 612 YRKLDDGSGAVGSWHTVRVPGSESELHLTELEPSSLYEVLMVARSAVGEGQPAMLTFRT 670
>sp|P16310|GHR_RAT Growth hormone receptor OS=Rattus norvegicus
OX=10116 GN=Ghr PE=1 SV=1
Length=638
Score = 97.2 bits (240), Expect = 2e-19, Method: Composition-based stats.
Identities = 44/211 (21%), Positives = 85/211 (40%), Gaps = 26/211 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA-------THKFADCKAK-RDT 178
KP+ C E + C W G + +L+ +++ +A T ++ +C
Sbjct 49 GKPRFTKCRSPELETFSCYWTEGDDHNLKVPGSIQLYYARRIAHEWTPEWKECPDYVSAG 108
Query 179 PTSCTVDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS----VINS 233
SC + S T ++ + + L D F V+P+PP L+ I+
Sbjct 109 ANSCYFNSSYTSIWIPYCIKLTTNGDL----LDEKCFTVDEIVQPDPPIGLNWTLLNISL 164
Query 234 EELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
+ ++++W P V IIL+Y IQY+ + + W + P +S + L
Sbjct 165 PGIRGDIQVSWQPPPSADVLKGWIILEYEIQYKEVNETKWKTMSP----IWSTSVPLYSL 220
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
+ E+ R+R + + +S++SE
Sbjct 221 RLDKEHEVRVRSRQRSFE-KYSEFSEVLRVT 250
Score = 49.5 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 55/243 (23%), Positives = 85/243 (35%), Gaps = 31/243 (13%)
Query 535 AVLEWDQLP-VDVQNG-FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
+ W P DV G I Y I Y+ + + T L SL D + VR+
Sbjct 171 IQVSWQPPPSADVLKGWIILEYEIQYKEVNETKWKTMSPIWSTSVPLYSLRLDKEHEVRV 230
Query 593 AA--YTDEGGKDGPE-FTFTTPKFAQGEI--EAIVVPVCLAFLL----TTLLGVLFCFNK 643
+ + E + E T P+ E P L + ++ + F+K
Sbjct 231 RSRQRSFEKYSEFSEVLRVTFPQMDTLAACEEDFRFPWFLIIIFGIFGVAVMLFVVIFSK 290
Query 644 RDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF-----------NSKDQMYSDGNFTDVS 692
+ IK I P VP P I P N K Y+D ++ +
Sbjct 291 QQRIKMLILPPVPVP---KIKGIDPDLLKEGKLEEVNTILGIHDNYKPDFYNDDSWVEFI 347
Query 693 VVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQN 752
++I+ D+K D L +EK S+GI G+ S R S D ++ +
Sbjct 348 ELDIDDADEKTEESDTDRLLSDDQEK------SAGILGAKDDDSGRTSCYDPDILDTDFH 401
Query 753 TSS 755
TS
Sbjct 402 TSD 404
>sp|P19941|GHR_RABIT Growth hormone receptor OS=Oryctolagus cuniculus
OX=9986 GN=GHR PE=1 SV=1
Length=638
Score = 96.8 bits (239), Expect = 3e-19, Method: Composition-based stats.
Identities = 45/217 (21%), Positives = 86/217 (40%), Gaps = 26/217 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA-------THKFADCKAK-RDT 178
KPK C E + C W G L++ +++ + T ++ +C
Sbjct 49 GKPKFTKCRSPELETFSCHWTDGVHHGLKSPGSVQLFYIRRNTQEWTQEWKECPDYVSAG 108
Query 179 PTSCTVDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS----VINS 233
SC + S T ++ + + N G V D F V+P+PP L+ ++
Sbjct 109 ENSCYFNSSYTSIWIPYCIKLT--NNGGMV--DQKCFSVEEIVQPDPPIGLNWTLLNVSL 164
Query 234 EELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
+ + +++ W P V I+L+Y +QY+ + + W + P +S V L
Sbjct 165 TGIHADIQVRWEPPPNADVQKGWIVLEYELQYKEVNETQWKMMDPVL----STSVPVYSL 220
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
+ EY R+R + + + ++SE + P
Sbjct 221 RLDKEYEVRVRSRQRSSE-KYGEFSEVLYVTLPQMSP 256
Score = 63.3 bits (152), Expect = 8e-09, Method: Composition-based stats.
Identities = 82/456 (18%), Positives = 146/456 (32%), Gaps = 83/456 (18%)
Query 447 RESVKKYILEW--CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
R + +++ EW C A + + T Y I +T
Sbjct 88 RRNTQEWTQEWKECPDYVSAGENSCYFNSSYTSIW----------IPYCIKLTNNGGMVD 137
Query 505 GSPESIKAYLKQAPPSKGPTVRTKKVGKN----EAVLEWDQLP-VDVQNG-FIRNYTIFY 558
S++ ++ PP V + + W+ P DVQ G + Y + Y
Sbjct 138 QKCFSVEEIVQPDPPIGL-NWTLLNVSLTGIHADIQVRWEPPPNADVQKGWIVLEYELQY 196
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA--YTDEGGKDGPE-FTFTTPKFAQ 615
+ + + + T + SL D Y VR+ + + E + E T P+ +
Sbjct 197 KEVNETQWKMMDPVLSTSVPVYSLRLDKEYEVRVRSRQRSSEKYGEFSEVLYVTLPQMSP 256
Query 616 GEIEA-IVVPVCLAFLL----TTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHT 670
E P L + T++ +F F+K+ IK I P VP P I P
Sbjct 257 FTCEEDFRFPWFLIIIFGIFGLTVMLFVFIFSKQQRIKMLILPPVPVP---KIKGIDPDL 313
Query 671 PPRHNFNS-----------KDQMYSDGNFTDVSVVEI-EANDKKPFPEDLKSLDLFKKEK 718
K + Y+D ++ + ++I + ++K + + L ++
Sbjct 314 LKEGKLEEVNTILAIQDSYKPEFYNDDSWVEFIELDIDDPDEKTEGSDTDRLLSNSHQKS 373
Query 719 INTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTS-STVQYSTVV-------------- 763
++ G S P I +D N S S V +
Sbjct 374 LSVLAAKDDDSG--RTSCYEPDILENDFNASDGCDGNSEVAQPQRLKGEADLLCLDQKNQ 431
Query 764 -HSGYRHQVPSVQV----FSRSESTQPLLDSE------------ERPEDL-------QLV 799
+S Y P+ Q + + +PLL E P L Q+
Sbjct 432 NNSPYHDVSPAAQQPEVVLAEEDKPRPLLTGEIESTLQAAPSQLSNPNSLANIDFYAQVS 491
Query 800 DHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSK 835
D G +L Q K SQ ++ P++ ++
Sbjct 492 DITPAGSVVLSPGQKNKAGNSQCDAHPEVVSLCQTN 527
Score = 39.8 bits (91), Expect = 0.11, Method: Composition-based stats.
Identities = 27/169 (16%), Positives = 51/169 (30%), Gaps = 14/169 (8%)
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVR--NLVGKSDAAVLTIPACDF 421
+ + WK + N + ++ N G D ++
Sbjct 89 RNTQEWTQEWKECPDYVSAGENSCYFNSSYTSIWIPYCIKLTNNGGMVDQKCFSV-EEIV 147
Query 422 QATHPV------MDLKAFPKDNMLWVEWTTPRES--VKKYILEWCVLSDKAPCITDWQQE 473
Q P+ +++ + V W P + K +I+ L K T W+
Sbjct 148 QPDPPIGLNWTLLNVSLTGIHADIQVRWEPPPNADVQKGWIVLEYELQYKEVNETQWKMM 207
Query 474 DGTVHRTYLRGNLAESKCYLITVTP--VYADGPGS-PESIKAYLKQAPP 519
D + + +L K Y + V ++ G E + L Q P
Sbjct 208 DPVLSTSVPVYSLRLDKEYEVRVRSRQRSSEKYGEFSEVLYVTLPQMSP 256
>sp|P54753|EPHB3_HUMAN Ephrin type-B receptor 3 OS=Homo sapiens
OX=9606 GN=EPHB3 PE=1 SV=2
Length=998
Score = 97.6 bits (241), Expect = 3e-19, Method: Composition-based stats.
Identities = 44/211 (21%), Positives = 71/211 (34%), Gaps = 22/211 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWAT--HKFADCKAK-R 176
P P+ + VNE + EW GGR+ L K A + C
Sbjct 339 VPSPPRGVISNVNE-TSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVE 397
Query 177 DTPTSCTVDYSTVY------FVNIEVWVEAENAL-GKVTSDHINFDP-VYKVKPNPPHNL 228
P + V+ V+A N + GK + + P
Sbjct 398 FVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVP 457
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
++ S L L+W P + +IL Y ++Y K S + S +S +
Sbjct 458 TLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIASTV-----TSQMNSVQLDG 512
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
L+P YV ++R G G +S +E +
Sbjct 513 LRPDARYVVQVRARTVAGYGQYSRPAEFETT 543
Score = 89.5 bits (220), Expect = 8e-17, Method: Composition-based stats.
Identities = 51/265 (19%), Positives = 87/265 (33%), Gaps = 27/265 (10%)
Query 386 KLTVNLTNDRYLATLTV-RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
N A++ N ++D+ + P + + + L +EW+
Sbjct 303 PCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPS--PPRGVISNVNETSLILEWS 360
Query 445 TPRESVKKYILEWCVL-------------SDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
PR+ + L + V+ S + ++ G R +L
Sbjct 361 EPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTR 420
Query 492 YLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDV 546
Y V V SP + QA PS+ PT+R + L W P +
Sbjct 421 YTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSW--APPER 478
Query 547 QNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP-- 604
NG I +Y + Y A V S L L D Y+V++ A T G
Sbjct 479 PNGVILDYEMKYFEK-SEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRP 537
Query 605 -EFTFTTPKFAQGEIEAIVVPVCLA 628
EF T+ + + + +P+ +
Sbjct 538 AEFETTSERGSGAQQLQEQLPLIVG 562
Score = 71.0 bits (172), Expect = 4e-11, Method: Composition-based stats.
Identities = 56/336 (17%), Positives = 99/336 (29%), Gaps = 39/336 (12%)
Query 117 GITIISGLPPEKPKNLSCIVNEGKKMR----CEWDGGRETHLETNFTLKSEWATHKFADC 172
G I + + P L C +G+ M C G E + + ++K
Sbjct 239 GTCIPNAVEVSVPLKLYCN-GDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQG 297
Query 173 KAKRDTPTSCTVDYSTVYFVNIEVWV-EAENALGKVTSDHINFDPVYKVKPNPPHNLSVI 231
+ C + + N + SD + D P+PP +
Sbjct 298 EG------PCLPCPPNSRTTSPAASICTCHNNFYRADSD--SADSACTTVPSPPRGV--- 346
Query 232 NSEELSSILKLTWTNPSI-KSVIILKYNIQYRTKDAST----------WSQIPPEDTAST 280
S + L L W+ P L YN+ + + + P T
Sbjct 347 ISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLT 406
Query 281 RSSFTVQDLKPFTEYVFRIRCMKE-DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
+ L T Y F ++ + GK + T + PS+ P+
Sbjct 407 ERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSG 466
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTL---TRWKSHLQNYTVNATKLTVNLTNDRY 396
+ W PP NG ILDYE+ + + +N+ +L + RY
Sbjct 467 SSLTL-----SW--APPERPNGVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARY 519
Query 397 LATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA 432
+ + R + G + + L+
Sbjct 520 VVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQE 555
>sp|Q78DX7|ROS1_MOUSE Proto-oncogene tyrosine-protein kinase ROS
OS=Mus musculus OX=10090 GN=Ros1 PE=1 SV=1
Length=2340
Score = 98.0 bits (242), Expect = 3e-19, Method: Composition-based stats.
Identities = 44/272 (16%), Positives = 75/272 (28%), Gaps = 25/272 (9%)
Query 362 KILDYEVT------LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT 415
Y ++ W S Q T +R + N G + VL
Sbjct 48 SGTRYNLSEACIHGCQFWNSVDQETCALKCNDTYATICERESCEVGCSNAEGSYEEEVLE 107
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
+ + + + W S KYI++W W +
Sbjct 108 STELPTAPFA------SSIGSHGVTLRWNPANISGVKYIIQWKYAQLPGS----WTFTET 157
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADG---PGSPESIKAYLKQAPPSKGP-TVRTKKVG 531
+Y L Y+ V ++ P P P + +
Sbjct 158 VSKLSYTVEPLHPFTEYIFRVVWIFTAQLHLYSPPSPSYRTHPYGVPETAPLILNMESWS 217
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
+ + W P G I Y + +I ++ + T + S +T Y
Sbjct 218 PDTVEVSW--APPHFPGGPILGYNL---RLISKNQKLDSGTQRTSFQFYSTLPNTTYRFS 272
Query 592 MAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
+AA + G E T TTP + E E +
Sbjct 273 IAAVNEVGEGPEAESTVTTPSPSVQEEEQWLF 304
Score = 89.5 bits (220), Expect = 1e-16, Method: Composition-based stats.
Identities = 69/432 (16%), Positives = 130/432 (30%), Gaps = 48/432 (11%)
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
LTW + + L Y ++ ++S + S + ++ L+PF+ Y+ +I
Sbjct 1469 LTWHGITHPTSTYLIYYMEANRANSSDRRH---KMLESQENVARIEGLQPFSMYMIQIAV 1525
Query 302 MKEDGKGYWSDWSE------EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW---- 351
Y+S+ E E G T S P I+ + ++ + W
Sbjct 1526 KN-----YYSEPLEHLPLGKEIQGQTK----SGVPGAVCHIN-ATVLSDTSLHVFWTESH 1575
Query 352 KTLPPFEA--NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
K P E+ ++ Y + + L + + L + V +
Sbjct 1576 KPNGPKESVRYQLVMSYLAPIPETPLRQGEFPSAKLSLLITKLSGGQLYVMKVLACHPEE 1635
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITD 469
+ P P P++ L ++W W L
Sbjct 1636 MWCTESHPVSVNMFDTPEKPSALVPENTSLQLDWKARSNVNLTGF--WFELQKWKYNEFY 1693
Query 470 WQQEDGTVHRTYL--RGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVR 526
+ + Y+ +L Y I V VY G S +++ K PSK +
Sbjct 1694 HVKASCSQGPVYVCNITDLQPYTSYNIRVVVVYTTGENSSSIPESFKTKAGVPSKPGIPK 1753
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD----------SSHTE 576
+ KN +W+ + + YT+ R I N++ SS
Sbjct 1754 LLEGSKNSI--QWE--KAEDNGSRLMYYTLEVRKGISNDSQNQSSRWKVVFNGSCSSICT 1809
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT--FTTPKFAQGEIEAIVVPVCLAFLLTTL 634
+ +L + R A + G + E + T + E + + +
Sbjct 1810 WRSKNLKG--TFQFRAVAANEIGLGEYSEISEDITLVEDGVWITETSFILTIIVGIFLVA 1867
Query 635 LGVLFCFNKRDL 646
L R L
Sbjct 1868 TVPLTFVWHRSL 1879
Score = 87.2 bits (214), Expect = 5e-16, Method: Composition-based stats.
Identities = 65/290 (22%), Positives = 103/290 (36%), Gaps = 35/290 (12%)
Query 133 SCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATH--KFADCKAKRDTPTSCTVDYSTVY 190
SC+ C + GR+ T + L SE H +F + + C Y+T+
Sbjct 33 SCLT------SCVTNLGRQLDSGTRYNL-SEACIHGCQFWNSVDQETCALKCNDTYATIC 85
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
V NA G + + P P S S + L W
Sbjct 86 ERE-SCEVGCSNAEGSYEEEVL----ESTELPTAPF-----ASSIGSHGVTLRWNP---A 132
Query 251 SVIILKYNIQYRTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
++ +KY IQ++ +W+ ++ S+TV+ L PFTEY+FR+ +
Sbjct 133 NISGVKYIIQWKYAQLPGSWTFTE----TVSKLSYTVEPLHPFTEYIFRVVWIFTAQLHL 188
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
+S S P P I + TV++ W PP G IL Y +
Sbjct 189 YSPPSPSYRTH-----PYGVPETAPLILNMESWSPDTVEVSW--APPHFPGGPILGYNLR 241
Query 370 LTRWKSHLQNYTVNAT-KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
L L + T + + L N Y ++ N VG+ A T+
Sbjct 242 LISKNQKLDSGTQRTSFQFYSTLPNTTYRFSIAAVNEVGEGPEAESTVTT 291
Score = 80.7 bits (197), Expect = 5e-14, Method: Composition-based stats.
Identities = 89/632 (14%), Positives = 175/632 (28%), Gaps = 128/632 (20%)
Query 104 NILTFGQLEQNVYGITIISGLP-PEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETN 157
+I FG ++G ++ S P P P+ +S + + + +W G N
Sbjct 546 HIEEFGFGNLVIFGSSVQS-YPLPGHPQEVSVLFGSREALI-QWTPPALAIGASPSAWQN 603
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVD-YSTVYFVNIEVWVEAENALGKVTSDHINFDP 216
+T + + + + + ++ V V A + G +
Sbjct 604 WTYEVKVYSQDILEITQVFSNISGTMLNVPELQSSTKYTVSVRASSPKGPGPWSAPSVGT 663
Query 217 VYKVKPNPPHNLSVINSEELSSILKLTWTNP--SIKSVIILK-----------YNIQYRT 263
PP ++V W+ P S L YN
Sbjct 664 TLVPATEPPFIMAVKEDGL--------WSKPLCSFGPGEFLSSDVGNVSDMDWYNNSLYY 715
Query 264 KDASTWSQIPPEDTASTRSSFTVQDL----------------KPFTEYVFR--------- 298
D + P + ++ + + YV +
Sbjct 716 SDTKGNVYVRPLNGMDISENYHIPSIVGAGALAFEWLGHFLYWAGKTYVIQRQSVLTGHT 775
Query 299 ------------IRCMKEDGKGYWSD-WSEEASGITYED--RPSKAPSFWYKIDPSHTQG 343
+ G YW+ +S E++ + E P K + T
Sbjct 776 DIVTHVKLLVNDMAVDSVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKKVIALTLD 835
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT---- 399
L W + N I Y L W T A T ++ + +
Sbjct 836 LSDGLLYW----LVQDNQCIHLYTAVLRGWSGGDATITEFAAWSTSEISQNALMYYSGRL 891
Query 400 --------LTV-----RNLVGKSDAAVLTIPACDFQATHP-VMDLKAFP----------- 434
+T R V S+ A + P + + P
Sbjct 892 FWINGFRIITAQEIGQRTSVSVSEPAKFNQFTIIQTSLKPLPGNFSSTPKVIPDPVQESS 951
Query 435 -----KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
+ + W P +V I+ + V +Q+ + L
Sbjct 952 FRIEGHTSSFQILWNEPP-AVDWGIVFYSVEFSTHSKFLIIEQQS---LPIFTVEGLEPY 1007
Query 490 KCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG------KNEAVLEWDQLP 543
+ ++VTP G G S+ ++ PS R + KNE V+E+
Sbjct 1008 TLFNLSVTPYTYWGKGQKTSLSFRAPESVPSAPENPRIFILSSGRYTKKNEVVVEFRWNK 1067
Query 544 VDVQNGFIRNYTIFYRTIIG--------NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
+NG + + IFY + + +V + L +++ + ++ +
Sbjct 1068 PKHENGVLTKFEIFYHISKQSGTNRSTEDWMSASVIPPVMSFQLEAVSPEYTVAFQVRVF 1127
Query 596 TDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
T +G GP K ++ + ++ +
Sbjct 1128 TSKG--PGPFSDIVMSKTSEIKPCPYLISLLG 1157
Score = 71.0 bits (172), Expect = 5e-11, Method: Composition-based stats.
Identities = 32/206 (16%), Positives = 66/206 (32%), Gaps = 14/206 (7%)
Query 142 MRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAE 201
+ W+ + ++ K + + + + ++ VW+
Sbjct 125 VTLRWNPANISGVKYIIQWKYAQLPGSWTFTETVSKLSYTVEPLHPFTEYIFRVVWIFTA 184
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
Y V P L++ + ++++W P IL YN++
Sbjct 185 QLHLYSPPSPSYRTHPYGVPETAPLILNMES--WSPDTVEVSWAPPHFPGGPILGYNLRL 242
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+K+ D+ + R+SF P T Y F I + E G+G E S +T
Sbjct 243 ISKNQKL-------DSGTQRTSFQFYSTLPNTTYRFSIAAVNEVGEGP-----EAESTVT 290
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTV 347
+ W + + R++
Sbjct 291 TPSPSVQEEEQWLFLSRKTSLRKRSL 316
Score = 60.6 bits (145), Expect = 7e-08, Method: Composition-based stats.
Identities = 36/237 (15%), Positives = 78/237 (33%), Gaps = 37/237 (16%)
Query 194 IEVWVEAENA--LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS 251
+ V A + + S ++ + P P L ++ L+L W S +
Sbjct 1624 YVMKVLACHPEEMWCTESHPVSVNMFDT--PEKPSALV-----PENTSLQLDWKARS--N 1674
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
V + + + + + + + + + DL+P+T Y R+ + G+
Sbjct 1675 VNLTGFWFELQKWKYNEFYHVKASCSQGPVYVCNITDLQPYTSYNIRVVVVYTTGENS-- 1732
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK-ILDYEVTL 370
S S T PSK P +G + + W+ E NG ++ Y + +
Sbjct 1733 -SSIPESFKTKAGVPSKP------GIPKLLEGSKN-SIQWE---KAEDNGSRLMYYTLEV 1781
Query 371 TRWKSHLQNYTVNATKLTVNL------------TNDRYLATLTVRNLVGKSDAAVLT 415
+ S+ + K+ N + N +G + + ++
Sbjct 1782 RKGISNDSQNQSSRWKVVFNGSCSSICTWRSKNLKGTFQFRAVAANEIGLGEYSEIS 1838
Score = 53.7 bits (127), Expect = 8e-06, Method: Composition-based stats.
Identities = 20/170 (12%), Positives = 47/170 (28%), Gaps = 18/170 (11%)
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY--LITV 496
+ W Y++ + + + + + + G L Y I V
Sbjct 1467 TNLTWHGITHPTSTYLIYYMEANRANSSDRRHKMLESQENVARIEG-LQPFSMYMIQIAV 1525
Query 497 TPVYADGPGSPE---SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF--- 550
Y++ I+ K P + + + W + NG
Sbjct 1526 KNYYSEPLEHLPLGKEIQGQTKSGVPGAVCHINATVLSDTSLHVFWTE--SHKPNGPKES 1583
Query 551 -----IRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
+ +Y + S+ ++ L+ LY++++ A
Sbjct 1584 VRYQLVMSYLAPIPETPLRQGEF--PSAKLSLLITKLSGGQLYVMKVLAC 1631
Score = 41.0 bits (94), Expect = 0.077, Method: Composition-based stats.
Identities = 31/130 (24%), Positives = 42/130 (32%), Gaps = 17/130 (13%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQL-------PVDVQNGFIRNYTIF-YRTIIGNETAVNV 570
P V G EA+++W P QN Y + Y I T V
Sbjct 568 PGHPQEVSVL-FGSREALIQWTPPALAIGASPSAWQNWT---YEVKVYSQDILEITQVFS 623
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFL 630
+ S T + L S T Y V + A + +G GP P + A P +A
Sbjct 624 NISGTMLNVPELQSSTKYTVSVRASSPKG--PGPWSA---PSVGTTLVPATEPPFIMAVK 678
Query 631 LTTLLGVLFC 640
L C
Sbjct 679 EDGLWSKPLC 688
Score = 37.9 bits (86), Expect = 0.54, Method: Composition-based stats.
Identities = 13/87 (15%), Positives = 23/87 (26%), Gaps = 6/87 (7%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGR-ETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
G+P P L+ + W + L+ K +
Sbjct 202 GVPETAPLILNMESWSPDTVEVSWAPPHFPGGPILGYNLRLISKNQKLDSGTQRTSFQF- 260
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVT 208
YST+ + A N +G+
Sbjct 261 ----YSTLPNTTYRFSIAAVNEVGEGP 283
>sp|P13590|NCAM1_CHICK Neural cell adhesion molecule 1 OS=Gallus
gallus OX=9031 GN=NCAM1 PE=1 SV=3
Length=1091
Score = 97.6 bits (241), Expect = 3e-19, Method: Composition-based stats.
Identities = 81/431 (19%), Positives = 130/431 (30%), Gaps = 65/431 (15%)
Query 40 LHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINR-------TASSVTFT 92
L T C + I WKT+ I E+ T+ R SS+T
Sbjct 321 LEDQITLTC-------EASGDPIPSITWKTSTRNISNEEKTLDGRIVVRSHARVSSLTLK 373
Query 93 DIASLNI-QLTCNILT-FGQLEQNVYGITIISGLPPE--KPK----------NLSCIVNE 138
+I + + C GQ Q +Y + P+ P N++C V
Sbjct 374 EIQYTDAGEYVCTASNTIGQDSQAMY---LEVQYAPKLQGPVAVYTWEGNQVNITCEVFA 430
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
W R+ L + S ++ K + S F N
Sbjct 431 YPSAVISWF--RDGQLLPS----SNYSNIKIYNTP---SASYLEVTPDSENDFGNY--NC 479
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKY 257
A N +G+ +S+ I V+ + P + S+ E SS ++ + P ILKY
Sbjct 480 TAVNRIGQESSEFIL------VQADTPSSPSIDRVEPYSSTARVEFDEPEATGGVPILKY 533
Query 258 NIQYRTKDASTWSQIPPEDTAST-RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
++R W + + + T+ LKP T Y R+ + G G S S+
Sbjct 534 KAEWRALGEGEWHSRLYDAKEANVEGTITISGLKPETTYSVRLSAVNGKGVGEISLPSD- 592
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL-----T 371
T R AP ++ V + I Y + +
Sbjct 593 --FKTQPVREPSAPKLEGQMGEDGNSIKVNVI------KQDDGGSPIRHYLIKYKAKHSS 644
Query 372 RWKSHLQNYTVNATKLTVNLT-NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
WK ++ + + +L N Y + N GKS A P
Sbjct 645 EWKPEIRLPSGIDHVMLKSLDWNAEYEVYVIAENQQGKSKPAHYAFRTSAQPTVIPASTS 704
Query 431 KAFPKDNMLWV 441
V
Sbjct 705 PTSGLGTAAIV 715
Score = 91.1 bits (224), Expect = 3e-17, Method: Composition-based stats.
Identities = 59/361 (16%), Positives = 113/361 (31%), Gaps = 33/361 (9%)
Query 386 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT 445
++T + ND T N +G+ + + + A + P + VE+
Sbjct 465 EVTPDSENDFGNYNCTAVNRIGQESSEFILVQADTPSSPSIDR---VEPYSSTARVEFDE 521
Query 446 PRE----SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
P + KY EW L + + ++ V T L Y + ++ V
Sbjct 522 PEATGGVPILKYKAEWRALGEGEWHSRLYDAKEANVEGTITISGLKPETTYSVRLSAVNG 581
Query 502 DGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G G + P + + ++ + + D IR+Y I Y+
Sbjct 582 KGVGEISLPSDFKTQPVREPSAPKLEGQMGEDGN-SIKVNVIKQDDGGSPIRHYLIKYKA 640
Query 561 IIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT-------- 610
+E + + S L SL + Y V + A +G + F T
Sbjct 641 KHSSEWKPEIRLPSGIDHVMLKSLDWNAEYEVYVIAENQQGKSKPAHYAFRTSAQPTVIP 700
Query 611 ----PKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQW 666
P G + + + + LL + V F + + I N+ KS
Sbjct 701 ASTSPTSGLGTAAIVGILIVIFVLLLVAVDVTCYFLNKCGLLMCIAVNL--CGKSGPGAK 758
Query 667 SPHTPPRHNFNSKDQMYSDGNFTDVSVVEIE-ANDKKPFPEDLKSLDLFKKEKINTEGHS 725
SKD+ +VE+ ++ P + K + + + H+
Sbjct 759 GKDMEEGKAAFSKDESKE-------PIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEHT 811
Query 726 S 726
+
Sbjct 812 A 812
>sp|Q97Z97|Y1033_SACS2 Kelch domain-containing protein SSO1033
OS=Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617
/ JCM 11322 / P2) OX=273057 GN=SSO1033 PE=3 SV=1
Length=725
Score = 96.8 bits (239), Expect = 3e-19, Method: Composition-based stats.
Identities = 71/405 (18%), Positives = 118/405 (29%), Gaps = 62/405 (15%)
Query 203 ALGKVTSDHINFDPVY-KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
+G SD + P PP + + + + L W + S Y I Y
Sbjct 304 GIGSSLSDVSALQLITFNFPPLPP---KITSYSAGNESVTLGWNPVRLSSG----YEIIY 356
Query 262 RTKDASTWSQ--IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
W+ +S+TV LK Y F + G S
Sbjct 357 -------WNNMGFNSSINVGNVTSYTVTGLKDGITYYFEVLAYNSIGYSSPS----SIIA 405
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK-ILDYEVTLTRWKSHLQ 378
+T P+ P + G V L W LPP + G +L Y V + S +
Sbjct 406 LTPASVPN--PPQLVSVKY----GNDNVTLNW--LPPTFSGGYLLLGYYVIVKNENSMVS 457
Query 379 NYTVNATKLTVNLTNDRYLATL--TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
++ VN+T LT++ + N +G S VLT+ T +
Sbjct 458 SHFVNSTSLTISNLTPNVTYNVFIYAVNKLGNSSPLVLTV----VPITKASVFAFITKLG 513
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV 496
N + V WTT + L + I+ G + Y + +
Sbjct 514 NGILVNWTTSFPANITLELY----NPNGNLISQIAAIKGNSSYLFRV----PQGNYTLVI 565
Query 497 TPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
+ G Y P P V G N + W + Y +
Sbjct 566 IASNSAGVSKYVYQVVY---YLPPASPQVSLIGFGNN-LYISW------NNEANVITYLV 615
Query 557 FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
+ ++ + + S+ Y+V++ G
Sbjct 616 YV------NNSLVYEGPSNSIVTN--ISNGTYLVKVIGVNPAGSS 652
Score = 96.1 bits (237), Expect = 5e-19, Method: Composition-based stats.
Identities = 44/235 (19%), Positives = 79/235 (34%), Gaps = 16/235 (7%)
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM-LWVEWTTPRESVKKYILEWCVLSDK 463
+G S + V + F + ++ N + + W R S I+ W +
Sbjct 304 GIGSSLSDVSALQLITFNFPPLPPKITSYSAGNESVTLGWNPVRLSSGYEIIYWNNMG-- 361
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
+ +Y L + Y V + G SP SI A + P+ P
Sbjct 362 -----FNSSINVGNVTSYTVTGLKDGITYYFEVLAYNSIGYSSPSSIIALTPASVPN-PP 415
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNG-FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
+ + K G + L W LP G + Y + + ++ V+S T T+S+L
Sbjct 416 QLVSVKYGNDNVTLNW--LPPTFSGGYLLLGYYVIVKNENSMVSSHFVNS--TSLTISNL 471
Query 583 TSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGV 637
T + Y V + A G + T + + A + + L+
Sbjct 472 TPNVTYNVFIYAVNKLG--NSSPLVLTVVPITKASVFAFITKLGNGILVNWTTSF 524
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 47/293 (16%), Positives = 91/293 (31%), Gaps = 45/293 (15%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P P+ +S + + W + + L + K + S ++
Sbjct 411 VPNPPQLVS-VKYGNDNVTLNWLPPTFSG---GYLLLGYYVIVKNENSMVSSHFVNSTSL 466
Query 185 DYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
S + V V++ A N LG + + P+ K +L + + +
Sbjct 467 TISNLTPNVTYNVFIYAVNKLGNSSPLVLTVVPITKAS-------VFAFITKLGNGILVN 519
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
WT ++ ++ + + SQI ++ F V P Y I
Sbjct 520 WTTSFPANI-----TLELYNPNGNLISQIAA-IKGNSSYLFRV----PQGNYTLVIIASN 569
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
G S+ + Y P+ S + + W EAN +
Sbjct 570 SAG------VSKYVYQVVYYLPPASP-------QVSLIGFGNNLYISWN----NEAN--V 610
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
+ Y V + ++ Y + + N++N YL + N G S + I
Sbjct 611 ITYLVYV----NNSLVYEGPSNSIVTNISNGTYLVKVIGVNPAGSSSPGIAVI 659
>sp|Q91571|EPB1A_XENLA Ephrin type-B receptor 1-A OS=Xenopus laevis
OX=8355 GN=ephb1-a PE=1 SV=1
Length=985
Score = 97.2 bits (240), Expect = 3e-19, Method: Composition-based stats.
Identities = 58/344 (17%), Positives = 108/344 (31%), Gaps = 36/344 (10%)
Query 386 KLTVNLTNDRYLATLTV-RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
+ N + + + + RN ++D P + ++ + + + +EW
Sbjct 288 QCPANSRSTSEASPICICRNGYYRADFDTPEAPCTSVPSG--PRNVISIVNETAITLEWH 345
Query 445 TPRESVKKYILEW-----------CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
PRE+ + +++ S + ++ G NL Y
Sbjct 346 PPRETGGRDDVDYNIVCKKCRADRRACSRCDDNVDFVPRQLGLTDTRVFISNLWAHTPYT 405
Query 494 ITVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
V SP S+ QA PS P + K L W Q + N
Sbjct 406 FETQAVNGVTNKSPFPPQHVSVNITTNQAAPSSVPIMHQVKATMKSITLSWPQQ--EQPN 463
Query 549 GFIRNYTIFYRTIIGNETAVNVDSSHT-EYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEF 606
G I +Y I Y +E ++ S T + V++ A T G GK +
Sbjct 464 GIILDYEIRYYEKDHHEFNSSLARSQTNTARRTGGRVWMFMSVQVRARTVAGYGKFSSKC 523
Query 607 TFTTP-------KFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPS 659
F T + + + F+++ + + C KR K+ ++ +
Sbjct 524 GFQTLTAEDYKSELREQLPLTGSAAAGVVFIVSLVAISIVCSRKRTYSKEAVYSD--KLQ 581
Query 660 KSHIAQWSPHTPPRHNFNSKDQMYSD----GNFTDVSVVEIEAN 699
+ SP + + + DVS V+IE
Sbjct 582 HYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEV 625
Score = 87.2 bits (214), Expect = 4e-16, Method: Composition-based stats.
Identities = 35/201 (17%), Positives = 65/201 (32%), Gaps = 18/201 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH-----LETNFTLKSEWATHKFADCKAKRDT- 178
P P+N+ IVNE + EW RET K + C D
Sbjct 324 VPSGPRNVISIVNE-TAITLEWHPPRETGGRDDVDYNIVCKKCRADRRACSRCDDNVDFV 382
Query 179 PTSCTVDYSTVY------FVNIEVWVEAENALGKVTS-DHINFDPVYKVKPNPPHNLSVI 231
P + + V+ +A N + + + P ++ ++
Sbjct 383 PRQLGLTDTRVFISNLWAHTPYTFETQAVNGVTNKSPFPPQHVSVNITTNQAAPSSVPIM 442
Query 232 NSEELS-SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + + + L+W + IIL Y I+Y KD + S ++ +
Sbjct 443 HQVKATMKSITLSWPQQEQPNGIILDYEIRYYEKDH---HEFNSSLARSQTNTARRTGGR 499
Query 291 PFTEYVFRIRCMKEDGKGYWS 311
+ ++R G G +S
Sbjct 500 VWMFMSVQVRARTVAGYGKFS 520
Score = 65.6 bits (158), Expect = 2e-09, Method: Composition-based stats.
Identities = 47/275 (17%), Positives = 86/275 (31%), Gaps = 39/275 (14%)
Query 182 CTVDYSTVYFVNIEVWVEAE---NALGKVTSDHINF--DPVYKV---KPNPP-----HNL 228
C + ++ N + + A+ N+ + I + Y+ P P
Sbjct 269 CKACPAAMFKANQGMGICAQCPANSRSTSEASPICICRNGYYRADFDTPEAPCTSVPSGP 328
Query 229 SVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTAS-------- 279
+ S + + L W P + YNI + A + +D
Sbjct 329 RNVISIVNETAITLEWHPPRETGGRDDVDYNIVCKKCRADRRACSRCDDNVDFVPRQLGL 388
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE-EASGITYEDRPSKAPSFWYKIDP 338
T + + +L T Y F + + + T + PS P I
Sbjct 389 TDTRVFISNLWAHTPYTFETQAVNGVTNKSPFPPQHVSVNITTNQAAPSSVP-----IMH 443
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKL-TVNLTNDRYL 397
+++ L W + NG ILDYE+ H N ++ ++ T T R
Sbjct 444 QVKATMKSITLSW--PQQEQPNGIILDYEIRYYEKDHHEFNSSLARSQTNTARRTGGRVW 501
Query 398 ----ATLTVRNLVG----KSDAAVLTIPACDFQAT 424
+ R + G S T+ A D+++
Sbjct 502 MFMSVQVRARTVAGYGKFSSKCGFQTLTAEDYKSE 536
>sp|P30530|UFO_HUMAN Tyrosine-protein kinase receptor UFO OS=Homo
sapiens OX=9606 GN=AXL PE=1 SV=4
Length=894
Score = 97.2 bits (240), Expect = 3e-19, Method: Composition-based stats.
Identities = 81/494 (16%), Positives = 136/494 (28%), Gaps = 60/494 (12%)
Query 53 KCMDYFHVNANYIVWKTNHFTIP-------------KEQYTIINRTASSVTFTDIASLNI 99
+C + W + + EQ I + +T ++
Sbjct 55 RCQLQVQGEPPEVHWLRDGQILELADSTQTQVPLGEDEQDDWIVVSQLRITSLQLSDTG- 113
Query 100 QLTCNILTFGQLEQNVYGITIISGLP--PEKPKNLSCIVNEGKKMRCEWDGGRETHLETN 157
Q C + Q + G + GLP E+P++ + N + C+ G E
Sbjct 114 QYQCLVFLGHQTFVSQPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCQAQGPPEP----- 168
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPV 217
+ W A P + EA NA G TS
Sbjct 169 --VDLLWLQDAVPLATAPGHGPQRS--LHVPGLNKTSSFSCEAHNAKGVTTS----RTAT 220
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS---------T 268
V P P NL +++ + L++ WT + +Q D
Sbjct 221 ITVLPQQPRNLHLVSR--QPTELEVAWTPGLSGIYPLTHCTLQAVLSDDGMGIQAGEPDP 278
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
+ + + L P T Y R+ C G S W+ T E P
Sbjct 279 PEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTSSQG---PSSWTHWLPVETPEGVPLG 335
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK-L 387
P + S T+ + W+ P G +L Y + + + + +
Sbjct 336 PPE-----NISATRNGSQAFVHWQE-PRAPLQGTLLGYRLAYQGQDTPEVLMDIGLRQEV 389
Query 388 TVNLTNDRY----LATLTVRNLVGKSDAAVLT-IPACDFQATHPVMDLKAFPKDNMLWVE 442
T+ L D + G ++ + A PV L P
Sbjct 390 TLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPGQAQPVHQLVKEPSTPAFSWP 449
Query 443 W-----TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
W + IL ++ + + + TV R L K Y T
Sbjct 450 WWYVLLGAVVAAACVLILALFLVHRRKKETRYGEVFEPTVERGELVVRYRVRKSYSRRTT 509
Query 498 PVYADGPGSPESIK 511
+ G E +K
Sbjct 510 EATLNSLGISEELK 523
Score = 76.4 bits (186), Expect = 9e-13, Method: Composition-based stats.
Identities = 48/238 (20%), Positives = 70/238 (29%), Gaps = 27/238 (11%)
Query 386 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT 445
L V N + N G + + TI P + L V WT
Sbjct 191 SLHVPGLNKTSSFSCEAHNAKGVTTSRTATITVL---PQQPRNLHLVSRQPTELEVAWTP 247
Query 446 PRESVKKYILEWCVL-------------SDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
Y L C L + P + G+L Y
Sbjct 248 --GLSGIYPLTHCTLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPY 305
Query 493 LITVTPVYADGPGSPESIK-AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
I V + GP S + P P + ++A + W + +Q G +
Sbjct 306 HIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPRAPLQ-GTL 364
Query 552 RNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTL---YMVRMAAYTDEGGKDGPEF 606
Y + Y+ E +++ E TL L D V +AAYT G DGP
Sbjct 365 LGYRLAYQGQDTPEVLMDIGLRQ-EVTLE-LQGDGSVSNLTVCVAAYTAAG--DGPWS 418
Score = 59.1 bits (141), Expect = 2e-07, Method: Composition-based stats.
Identities = 25/194 (13%), Positives = 50/194 (26%), Gaps = 22/194 (11%)
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA 411
+ PP E + + + +L + Y + + G S
Sbjct 275 EPDPPEEPL--------------TSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSW 320
Query 412 A-VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW 470
L + + P ++ A + +V W PR ++ +L + +
Sbjct 321 THWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPRAPLQGTLLGYRLAYQGQDTPEVL 380
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS---PESIKAYLKQAPPSKGPTVRT 527
T + V A G G P ++A+ P + V
Sbjct 381 MDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAW----RPGQAQPVHQ 436
Query 528 KKVGKNEAVLEWDQ 541
+ W
Sbjct 437 LVKEPSTPAFSWPW 450
>sp|Q6AZB0|BOC_MOUSE Brother of CDO OS=Mus musculus OX=10090 GN=Boc
PE=1 SV=2
Length=1110
Score = 97.2 bits (240), Expect = 3e-19, Method: Composition-based stats.
Identities = 53/344 (15%), Positives = 106/344 (31%), Gaps = 61/344 (18%)
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
+ P++AP + T + +LVW+ + IL Y V + + ++T+
Sbjct 463 QVAPAEAP---IILSSPRTSKTDSYELVWRPRHEGSSRTPILYYVVKHRKVTNSSDDWTI 519
Query 383 -----NATKLTVNLT--NDRYLATLTVRNLVGKSDAAVLTIPA----------------- 418
N +LT+ Y + N G+ A++T
Sbjct 520 SGIPANQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIVASKEQQIQ 579
Query 419 -----------------CDFQATHPVMDLKAFPKDNMLWVEWTTPRE---SVKKYILEWC 458
P + + ++V W ++ + +E+
Sbjct 580 RDDPGASLQSSSQPDHGRLSPPEAPDRPTISTASETSVYVTWIPRGNGGFPIQSFRVEYK 639
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES------IKA 512
L I + + G L + Y V + G P + +
Sbjct 640 KLKKVGDWILATSAIPPSRLSVEITG-LEKGISYKFRVRALNMLGESEPSAPSRPYVVSG 698
Query 513 YLKQA--PPSKGPTVR-TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET--- 566
Y + P GP + T V + +L+W +P N I + I+YR +
Sbjct 699 YSGRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDNDSDY 758
Query 567 -AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT 609
V+ +++S L +T Y ++M + + G +
Sbjct 759 KKDMVEGDRYWHSISHLQPETSYDIKMQCFNEGGESEFSNVMIC 802
Score = 89.1 bits (219), Expect = 1e-16, Method: Composition-based stats.
Identities = 55/377 (15%), Positives = 99/377 (26%), Gaps = 50/377 (13%)
Query 125 PPEKPKNLSC-IVNEGKKMRCEWDGGRETHLET---NFTLKSEWATHKFADCKAKRDTPT 180
P E P LS ++ W E T + +K T+ D P
Sbjct 466 PAEAPIILSSPRTSKTDSYELVWRPRHEGSSRTPILYYVVKHRKVTNSSDD-WTISGIPA 524
Query 181 SCTVDYSTVYFVN--IEVWVEAENALGKVTSDHINFDPVYKVKPN--------------- 223
+ T EV + A N G+ + + F + KP
Sbjct 525 NQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIVASKEQQIQRDDPG 584
Query 224 ---------------PPHNL-SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS 267
PP S + + +TW I + ++Y+
Sbjct 585 ASLQSSSQPDHGRLSPPEAPDRPTISTASETSVYVTWIPRGNGGFPIQSFRVEYKKLKKV 644
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
+ +R S + L+ Y FR+R + G+ S S Y R
Sbjct 645 GDWILATSAIPPSRLSVEITGLEKGISYKFRVRALNMLGESEPSAPSRPYVVSGYSGRVY 704
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA--- 384
+ P I + T+ L W +P N I + + S +
Sbjct 705 ERPVAGPYITFTDAVNETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDNDSDYKKDMVE 764
Query 385 -----TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNML 439
++ Y + N G+S+ + + I + + +
Sbjct 765 GDRYWHSISHLQPETSYDIKMQCFNEGGESEFSNVMICETKARKFSG----QPGRPPPLT 820
Query 440 WVEWTTPRESVKKYILE 456
P + +
Sbjct 821 LAPPQPPPLETMERPVG 837
Score = 81.8 bits (200), Expect = 2e-14, Method: Composition-based stats.
Identities = 53/389 (14%), Positives = 106/389 (27%), Gaps = 68/389 (17%)
Query 203 ALGKVTSDHINFDPVYKVKP-NPPHNLSVINSEELSSILKLTWTNPSIKSV--IILKYNI 259
V + +V P P LS + +L W S IL Y +
Sbjct 447 PTSSVQPTSLKCPGEEQVAPAEAPIILS-SPRTSKTDSYELVWRPRHEGSSRTPILYYVV 505
Query 260 QYR--TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG--------- 308
++R T + W+ + + T+ L P + Y + G+G
Sbjct 506 KHRKVTNSSDDWT---ISGIPANQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRT 562
Query 309 ---YWSDWSEEASGITYEDRP------SKAPSFWYKIDPS-------HTQGYRTVQLVWK 352
+ D P S P P T +V + W
Sbjct 563 GRRPKPEIVASKEQQIQRDDPGASLQSSSQPDHGRLSPPEAPDRPTISTASETSVYVTWI 622
Query 353 TLPPFEANG--KILDYEVTLTRWKSH----LQNYTVNATKLTVNLT----NDRYLATLTV 402
NG I + V + K L + ++L+V +T Y +
Sbjct 623 P----RGNGGFPIQSFRVEYKKLKKVGDWILATSAIPPSRLSVEITGLEKGISYKFRVRA 678
Query 403 RNLVGKSDAAVLTIPAC---------DFQATHPVMDLKAFPKDNMLWVEW-----TTPRE 448
N++G+S+ + + P + P + + + ++W +
Sbjct 679 LNMLGESEPSAPSRPYVVSGYSGRVYERPVAGPYITFTDAVNETTIMLKWMYIPASNNNT 738
Query 449 SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE 508
+ + + + +G + + +L Y I + G
Sbjct 739 PIHGFYIYYRPTDSDNDSDYKKDMVEGDRYWHSI-SHLQPETSYDIKMQCFNEGGESEFS 797
Query 509 SIKAYLKQAP-----PSKGPTVRTKKVGK 532
++ +A P + P +
Sbjct 798 NVMICETKARKFSGQPGRPPPLTLAPPQP 826
Score = 76.8 bits (187), Expect = 7e-13, Method: Composition-based stats.
Identities = 39/241 (16%), Positives = 71/241 (29%), Gaps = 22/241 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADCKAKRDTPTS-- 181
PPE P + + W +F ++ + A P S
Sbjct 600 PPEAPDRPTISTASETSVYVTWIPRGNGGFPIQSFRVEYKKLKKVGDWILATSAIPPSRL 659
Query 182 CTVDYSTVYFVNIEVWVEAENALG----KVTSDHINFDPVY-KVKPNPPHNLSVINSEEL 236
++ + V A N LG S +V P + ++ +
Sbjct 660 SVEITGLEKGISYKFRVRALNMLGESEPSAPSRPYVVSGYSGRVYERPVAGPYITFTDAV 719
Query 237 S-SILKLTW--TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
+ + + L W S + I + I YR D+ S + R ++ L+P T
Sbjct 720 NETTIMLKWMYIPASNNNTPIHGFYIYYRPTDSDNDSDYKKDMVEGDRYWHSISHLQPET 779
Query 294 EYVFRIRCMKEDGKGYWSDWS-----------EEASGITYEDRPSKAPSFWYKIDPSHTQ 342
Y +++C E G+ +S+ + P + P P T
Sbjct 780 SYDIKMQCFNEGGESEFSNVMICETKARKFSGQPGRPPPLTLAPPQPPPLETMERPVGTG 839
Query 343 G 343
Sbjct 840 A 840
Score = 56.8 bits (135), Expect = 9e-07, Method: Composition-based stats.
Identities = 25/111 (23%), Positives = 42/111 (38%), Gaps = 5/111 (5%)
Query 515 KQAPPSKGPTVRTKKVGK--NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV-- 570
+Q P++ P + + + L W I Y + +R + + +
Sbjct 462 EQVAPAEAPIILSSPRTSKTDSYELVWRPRHEGSSRTPILYYVVKHRKVTNSSDDWTISG 521
Query 571 -DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
++ TL+ L +LY V MAAY G TF T + + EI A
Sbjct 522 IPANQHRLTLTRLDPGSLYEVEMAAYNCAGEGQTAMVTFRTGRRPKPEIVA 572
>sp|A2A863|ITB4_MOUSE Integrin beta-4 OS=Mus musculus OX=10090
GN=Itgb4 PE=1 SV=1
Length=1818
Score = 97.6 bits (241), Expect = 3e-19, Method: Composition-based stats.
Identities = 78/563 (14%), Positives = 165/563 (29%), Gaps = 73/563 (13%)
Query 110 QLEQNVYGITIISGLPP----EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA 165
+ ++++ T+ S PP P+N + +K+ W + +K W
Sbjct 1109 ETDRSLINQTLSSPPPPHGDLGAPQNPNAKAAGSRKIHFNWLP--PPGKPMGYRVKY-WI 1165
Query 166 THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPP 225
D+ + + + E+ V A A G+ + ++ P+ P
Sbjct 1166 QGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAYGAQGEGPYSSLVSCRTHQEVPSEP 1225
Query 226 HNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT---ASTRS 282
L+ + S++ +L+W P+ + I Y + Y + P +
Sbjct 1226 GRLA--FNVVSSTVTQLSWAEPAETNGEITAYEVCYGLVNEDNRPIGPMKKVLVDNPKNR 1283
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI----TYEDRPSKAPSFWYKIDP 338
+++L+ Y + ++ G W E I T RP P
Sbjct 1284 MLLIENLRESQPYRYTVKARNGAG------WGPEREAIINLATQPKRPMSIPIIPDIPIV 1337
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYE--VTLTRWKSHLQNYTVNA---TKLTVNLTN 393
G E L Y V + S + + + K L
Sbjct 1338 DAQGG--------------EDYENFLMYSDDVLRSPASSQRPSVSDDTGCGWKFEPLLGE 1383
Query 394 DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKY 453
+ L +T R + + A ++ + W+ TPR ++
Sbjct 1384 ELDLRRVTWR----LPPELIPRLSASSGRSDEDGSVAGGVEGEGSGWIRGATPR-PPGEH 1438
Query 454 ILEWCVL--SDKAPCITDWQQEDGTVHRTYLRGNLAESKC---------YLITVTPVYAD 502
++ + + + T+L +L+ Y ++
Sbjct 1439 LVNGRMDFAYPGSANSLHRMTAANVAYGTHLSPHLSHRVLSTSSTLTRDYHSLTRTEHSH 1498
Query 503 GPGSP---------ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
P S + P + +G + W + D +
Sbjct 1499 SGTLPRDYSTLTSLSSQDSRGAVGVPDTPTRLVFSALGPTSLKVSWQEPQCDR---MLLG 1555
Query 554 YTIFYRTIIGNETAVN--VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP 611
Y++ Y+ + G E + T + L + Y+ R+ A + EG G E
Sbjct 1556 YSVEYQLLNGGEMHRLNIPNPGQTSVVVEDLLPNHSYVFRVRAQSQEGW--GREREGVIT 1613
Query 612 KFAQGEIEAIVVPVCLAFLLTTL 634
+Q ++ + P+ + +
Sbjct 1614 IESQVHPQSPLCPLPGSAFTLST 1636
Score = 96.1 bits (237), Expect = 1e-18, Method: Composition-based stats.
Identities = 41/243 (17%), Positives = 72/243 (30%), Gaps = 26/243 (11%)
Query 386 KLTVNLTNDRYLATL----TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK------ 435
+ V L+N ++ A L T ++G+ D ++ + P P+
Sbjct 1080 RFQVQLSNPKFGARLGQPSTTTVILGEHDETDRSLINQTLSSPPPPHGDLGAPQNPNAKA 1139
Query 436 --DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
+ W P Y +++ + D + +V T NL Y
Sbjct 1140 AGSRKIHFNWLPPPGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELT----NLYPYCDYE 1195
Query 494 ITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
+ V A G G + Q PS+ + V L W + NG I
Sbjct 1196 MKVCAYGAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAE--PAETNGEIT 1253
Query 553 NYTIFY-------RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
Y + Y R I + + + + + +L Y + A G E
Sbjct 1254 AYEVCYGLVNEDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPERE 1313
Query 606 FTF 608
Sbjct 1314 AII 1316
Score = 94.9 bits (234), Expect = 2e-18, Method: Composition-based stats.
Identities = 51/294 (17%), Positives = 89/294 (30%), Gaps = 41/294 (14%)
Query 367 EVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
V S ++ V +T T LT D + T T + G T+ + Q +
Sbjct 1462 NVAYGTHLSPHLSHRVLSTSST--LTRDYHSLTRTEHSHSGTLPRDYSTLTSLSSQDSRG 1519
Query 427 VMDLKAFPK--------DNMLWVEWTTPR--ESVKKYILEWCVLSDKAPCITDWQQEDGT 476
+ + P L V W P+ + Y +E+ +L+
Sbjct 1520 AVGVPDTPTRLVFSALGPTSLKVSWQEPQCDRMLLGYSVEYQLLNGGE---MHRLNIPNP 1576
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPG-------------------SPESIKAYLKQA 517
+ + +L + Y+ V +G G P A+
Sbjct 1577 GQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLST 1636
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG----NETAVNVDSS 573
P + GP + + + L W+ NG I Y + G V+ D+
Sbjct 1637 PSAPGP-LVFTALSPDSLQLSWE--RPRRPNGDILGYLVTCEMAQGGAPARTFRVDGDNP 1693
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
+ T+ L+ + Y ++ A T EG E T G + L
Sbjct 1694 ESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQVGGPFPQLGSHSGL 1747
Score = 85.3 bits (209), Expect = 2e-15, Method: Composition-based stats.
Identities = 48/228 (21%), Positives = 81/228 (36%), Gaps = 37/228 (16%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P+ P L + LK++W P ++L Y+++Y+ + ++ + +
Sbjct 1524 PDTPTRLVFSALG--PTSLKVSWQEP-QCDRMLLGYSVEYQLLNGGEMHRLNIPN--PGQ 1578
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKG--------------YWSDWSE-EASGITYEDRP 326
+S V+DL P YVFR+R ++G G S S T
Sbjct 1579 TSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPS 1638
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV---- 382
+ P + + P ++QL W+ P NG IL Y VT + T
Sbjct 1639 APGPLVFTALSPD------SLQLSWE--RPRRPNGDILGYLVTCEMAQGGAPARTFRVDG 1690
Query 383 --NATKLTVNLTND--RYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
++LTV ++ Y + R G I + Q P
Sbjct 1691 DNPESRLTVPGLSENVPYKFKVQARTTEGFGPE-REGIITIESQVGGP 1737
Score = 75.3 bits (183), Expect = 3e-12, Method: Composition-based stats.
Identities = 45/305 (15%), Positives = 87/305 (29%), Gaps = 33/305 (11%)
Query 41 HSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQ 100
S + + H++ + + + Y + RT S
Sbjct 1450 GSANSLHRMTAANVAYGTHLSPHLSHRVLSTSSTLTRDYHSLTRTEHS---HSGTLPRDY 1506
Query 101 LTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL 160
T L Q + G+ P+ P L ++ W + + +++
Sbjct 1507 STLTSL-SSQDSRGAVGV-------PDTPTRLVFSALGPTSLKVSWQEPQCDRMLLGYSV 1558
Query 161 KSEWA-THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYK 219
+ + + TS V+ + + V A++ G +
Sbjct 1559 EYQLLNGGEMHRLNIPNPGQTSVVVE-DLLPNHSYVFRVRAQSQEGWGREREGVITIESQ 1617
Query 220 VKPNPP--------HNLS-------VINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK 264
V P P LS ++ + L+L+W P + IL Y +
Sbjct 1618 VHPQSPLCPLPGSAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDILGYLVTCEMA 1677
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
++ D + S TV L Y F+++ +G G E IT E
Sbjct 1678 QGGAPARTFRVDGDNPESRLTVPGLSENVPYKFKVQARTTEGFGP-----EREGIITIES 1732
Query 325 RPSKA 329
+
Sbjct 1733 QVGGP 1737
>sp|Q63132|ROS1_RAT Proto-oncogene tyrosine-protein kinase ROS
OS=Rattus norvegicus OX=10116 GN=Ros1 PE=2 SV=1
Length=2338
Score = 97.6 bits (241), Expect = 3e-19, Method: Composition-based stats.
Identities = 73/442 (17%), Positives = 141/442 (32%), Gaps = 57/442 (13%)
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
LTW + + L Y ++ ++S E S + ++ L+PF+ YV +I
Sbjct 1468 LTWHGITTPTSTYLVYYMEANRANSSDRKHNMLE---SQENVARIEGLQPFSTYVIQIAV 1524
Query 302 MKEDGKGYWSDWSE------EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
Y+SD E E G T S P I+ + ++ + W
Sbjct 1525 KN-----YYSDPLEHLSLGKEIQGKTK----SGVPGAVCHIN-ATVLSDTSLLVFWTESH 1574
Query 356 PFEANGKILDYEVTLTRWK----SHLQNYTVNATKLTVNLTN----DRYLATLTVRNLVG 407
+++ Y++ ++ + L+ + +L++ +T +Y+ + +
Sbjct 1575 KPNGPKELVRYQLVMSYLAPIPETPLRQDEFPSARLSLLVTKLSGGQQYVLKILACHS-- 1632
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
+ + P P P++ L ++W P + W L
Sbjct 1633 EEMWCTESHPVSVNMFDTPEKPSALVPENTSLLLDWKAPSNANLTRF--WFELQKWKYSE 1690
Query 468 TDWQQEDGTVHRTYL--RGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPT 524
+ + Y+ NL Y I V VY G S +++ K PSK
Sbjct 1691 FYHVKASCSQGPVYVCNIANLQPYTPYNIRVVVVYTTGENSSSIPESFKTKAGVPSKPGI 1750
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD----------SSH 574
+ + KN +W+ + + YT+ R I N++ SS
Sbjct 1751 PKLLEGSKNSI--QWE--KAEDNGNRLMYYTLEVRKSISNDSRDQSLRWTAVFNGSCSSI 1806
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT--FTTPKFA-----QGEIEAIVVPVCL 627
+ +L + R A G + E + T + I I+V + L
Sbjct 1807 CTWRSKNLKG--TFQFRAVASNAIGFGEYSEISEDITLVEDGFWITETSFILTIIVGIFL 1864
Query 628 AFLLTTLLGVLFCFNKRDLIKK 649
+ K+
Sbjct 1865 VATVPLTFVWHRSLKNHKATKE 1886
Score = 97.2 bits (240), Expect = 5e-19, Method: Composition-based stats.
Identities = 36/202 (18%), Positives = 61/202 (30%), Gaps = 13/202 (6%)
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
P + N + + W S KYI++W W + +Y+
Sbjct 111 PTAPFASSIGSNGVTLRWNPANISGVKYIIQWKYAQLPGS----WAYTETVSKLSYMVEP 166
Query 486 LAESKCYLITVTPVYADG---PGSPESIKAYLKQAPPSKGPTVR-TKKVGKNEAVLEWDQ 541
L Y+ V ++ P P P + + + + W
Sbjct 167 LHPFTEYIFRVVWIFTAQLHLYSPPSPSYRTHPYGVPETAPFITNIESSSPDTVEVSW-- 224
Query 542 LPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
P G I Y + +I ++ + T + S +T Y +AA + G
Sbjct 225 APPYFPGGPILGYNL---RLISKTQKLDSGTQRTSFQFYSTLPNTTYRFSIAAVNEVGEG 281
Query 602 DGPEFTFTTPKFAQGEIEAIVV 623
E TTP A E E +
Sbjct 282 PEAESMITTPSPAVQEEEQWLF 303
Score = 86.1 bits (211), Expect = 1e-15, Method: Composition-based stats.
Identities = 61/289 (21%), Positives = 100/289 (35%), Gaps = 33/289 (11%)
Query 133 SCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATH-KFADCKAKRDTPTSCTVDYSTVYF 191
SC+ C + GR+ T + L +F + + C Y T+
Sbjct 32 SCLT------SCVTNLGRQLDSGTRYNLSEACIQGCQFWNSIDQEKCALKCNDTYVTICE 85
Query 192 VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS 251
V NA G + ++ P P S S+ + L W +
Sbjct 86 RE-SCEVGCSNAEGSYEEEVLD----NTELPTAPF-----ASSIGSNGVTLRWNP---AN 132
Query 252 VIILKYNIQYRTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
+ +KY IQ++ +W+ ++ S+ V+ L PFTEY+FR+ + +
Sbjct 133 ISGVKYIIQWKYAQLPGSWAYTE----TVSKLSYMVEPLHPFTEYIFRVVWIFTAQLHLY 188
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S S P P I + TV++ W PP+ G IL Y + L
Sbjct 189 SPPSPSYRTH-----PYGVPETAPFITNIESSSPDTVEVSW--APPYFPGGPILGYNLRL 241
Query 371 TRWKSHLQNYTVNAT-KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
L + T + + L N Y ++ N VG+ A I
Sbjct 242 ISKTQKLDSGTQRTSFQFYSTLPNTTYRFSIAAVNEVGEGPEAESMITT 290
Score = 76.0 bits (185), Expect = 1e-12, Method: Composition-based stats.
Identities = 89/632 (14%), Positives = 175/632 (28%), Gaps = 128/632 (20%)
Query 104 NILTFGQLEQNVYGITIISGLP-PEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETN 157
+I FG ++G ++ S P P P+ +S + + + +W G N
Sbjct 545 HIEEFGFGNLVIFGSSVQS-YPLPGHPQEVSVLFGSREALI-QWKPPILAIGASPSAWQN 602
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVD-YSTVYFVNIEVWVEAENALGKVTSDHINFDP 216
+T + + ++ + + ++ V V A + G +
Sbjct 603 WTYEVKVSSQDILETTQVFLNISRTVLNVPKLQSSTKYMVSVRASSPKGPGPWSEPSVGT 662
Query 217 VYKVKPNPPHNLSVINSEELSSILKLTWTNP--SIKSVIILK-----------YNIQYRT 263
PP ++V W+ P S L YN
Sbjct 663 TLVPATEPPFIMAVKEDGL--------WSKPLSSFGPGEFLSSDVGNVSDMDWYNNSLYY 714
Query 264 KDASTWSQIPPEDTASTRSSFTVQDL----------------KPFTEYVFR--------- 298
D + P + ++ + + YV +
Sbjct 715 SDTKGNVYVRPLNGMDISENYHISSIAGACALAFEWLGHFLYWAGKTYVIQRQSVLTGHT 774
Query 299 ------------IRCMKEDGKGYWSD-WSEEASGITYED--RPSKAPSFWYKIDPSHTQG 343
+ G YW+ +S E++ + E P K + T
Sbjct 775 DIVTHVKLLVNDMAVDPVGGYLYWTTLYSVESTRLNGESSLVLQAQPWLSGKKVIALTLD 834
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT---- 399
L W + N I Y L W T A T ++ + +
Sbjct 835 LSDGLLYW----LVQDNQCIHLYTAVLRGWSGADATITEFAAWSTSEISQNALMYYSGRL 890
Query 400 --------LTV-----RNLVGKSDAAVLTIPACDFQATHP-VMDLKAFP----------- 434
+T R V S+ + P + + P
Sbjct 891 FWINGFRIITAQEIGQRTSVSVSEPGKFNQFTIIQTSLKPLPGNFSSTPTVIPDSVQESS 950
Query 435 -----KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
+ + W P +V I+ + V +Q+ + L
Sbjct 951 FRIEGHTSSFRILWNEPP-AVDWGIVFYSVEFSAHSKFLAIEQQS---LPVFTVEGLEPY 1006
Query 490 KCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG------KNEAVLEWDQLP 543
+ ++VTP G G S+ ++ PS R + KNE V+E+
Sbjct 1007 ALFNLSVTPYTYWGKGQKTSLSFRAPESVPSAPENPRIFILSLGRYTRKNEVVVEFRWNK 1066
Query 544 VDVQNGFIRNYTIFYRTIIG--------NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
+NG + IFY + +V+V + L +++ + ++ +
Sbjct 1067 PKHENGVLTKSEIFYHISKQSGTNKSTEDWVSVSVTPPVMSFQLEAMSPGYIVSFQVRVF 1126
Query 596 TDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
T +G GP K ++ + ++ +
Sbjct 1127 TSKG--PGPFSDIVMSKTSEIKPCPYLISLLG 1156
Score = 71.8 bits (174), Expect = 2e-11, Method: Composition-based stats.
Identities = 50/339 (15%), Positives = 102/339 (30%), Gaps = 35/339 (10%)
Query 15 FLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTI 74
+LT + ++ C +IS + S+ CV + + I
Sbjct 6 WLTPKPATFVVLGCVWISVAQGTIL--SSCLTSCVTNLGRQLDSGTR-----YNLSEACI 58
Query 75 PKEQY-TIINRTASSV----TFTDIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPEK 128
Q+ I++ ++ T+ I ++ C+ E+ + + P
Sbjct 59 QGCQFWNSIDQEKCALKCNDTYVTICERESCEVGCSNAEGSYEEEVLDNTEL-----PTA 113
Query 129 PKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYST 188
P + W+ + ++ K +A + +
Sbjct 114 PF---ASSIGSNGVTLRWNPANISGVKYIIQWKYAQLPGSWAYTETVSKLSYMVEPLHPF 170
Query 189 VYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
++ VW+ Y V P ++ + ++++W P
Sbjct 171 TEYIFRVVWIFTAQLHLYSPPSPSYRTHPYGVPETAPFITNIES--SSPDTVEVSWAPPY 228
Query 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
IL YN++ +K D+ + R+SF P T Y F I + E G+G
Sbjct 229 FPGGPILGYNLRLISKTQKL-------DSGTQRTSFQFYSTLPNTTYRFSIAAVNEVGEG 281
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV 347
E S IT + W + + R++
Sbjct 282 P-----EAESMITTPSPAVQEEEQWLFLSRKTSLRKRSL 315
Score = 57.6 bits (137), Expect = 7e-07, Method: Composition-based stats.
Identities = 36/246 (15%), Positives = 69/246 (28%), Gaps = 12/246 (5%)
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI 454
Y + L A + A AT+ + LK P + W Y+
Sbjct 1424 AYSSALQPFPDKAYLSVASNMVEASILNATNTSLILKLPPVKT--NLTWHGITTPTSTYL 1481
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY--LITVTPVYADGPGSPE---S 509
+ + + + + + G L Y I V Y+D
Sbjct 1482 VYYMEANRANSSDRKHNMLESQENVARIEG-LQPFSTYVIQIAVKNYYSDPLEHLSLGKE 1540
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI--FYRTIIGNE-- 565
I+ K P + + ++ W + + Y + Y I
Sbjct 1541 IQGKTKSGVPGAVCHINATVLSDTSLLVFWTESHKPNGPKELVRYQLVMSYLAPIPETPL 1600
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPV 625
S+ ++ L+ Y++++ A E + F E + +VP
Sbjct 1601 RQDEFPSARLSLLVTKLSGGQQYVLKILACHSEEMWCTESHPVSVNMFDTPEKPSALVPE 1660
Query 626 CLAFLL 631
+ LL
Sbjct 1661 NTSLLL 1666
Score = 55.2 bits (131), Expect = 3e-06, Method: Composition-based stats.
Identities = 32/232 (14%), Positives = 62/232 (27%), Gaps = 34/232 (15%)
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+ C +G S E + + P+ + + G V L W
Sbjct 91 VGCSNAEG-------SYEEEVLDNTELPTAP--------FASSIGSNGVTLRWNP----- 130
Query 359 ANGKILDYEVTLTRWK-SHLQNYTVNATKLTVNL----TNDRYLATL----TVRNLVGKS 409
AN + Y + + YT +KL+ + Y+ + T + +
Sbjct 131 ANISGVKYIIQWKYAQLPGSWAYTETVSKLSYMVEPLHPFTEYIFRVVWIFTAQLHLYSP 190
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITD 469
+ T P + + + V W P IL + + D
Sbjct 191 PSPSYRTHPYGVPETAPFITNIESSSPDTVEVSWAPPY-FPGGPILGYNLRLISKTQKLD 249
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
GT ++ + + Y ++ V G G +
Sbjct 250 ----SGTQRTSFQFYSTLPNTTYRFSIAAVNEVGEGPEAESMITTPSPAVQE 297
Score = 50.2 bits (118), Expect = 9e-05, Method: Composition-based stats.
Identities = 36/227 (16%), Positives = 77/227 (34%), Gaps = 22/227 (10%)
Query 101 LTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL 160
L C+ E + + + + P+ S +V E + +W +L +
Sbjct 1628 LACHSEEMWCTESHPVSVNMF-----DTPEKPSALVPENTSLLLDWKAPSNANLTRFWFE 1682
Query 161 KSEWATHKFADCKA-KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD-HINFDPVY 218
+W +F KA P + + + V G+ +S +F
Sbjct 1683 LQKWKYSEFYHVKASCSQGPVYVCNIANLQPYTPYNIRVVVVYTTGENSSSIPESFKTKA 1742
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK-------DASTWSQ 271
V P+ P ++ + S + W ++ Y ++ R + W+
Sbjct 1743 GV-PSKPGIPKLLEGSKNS----IQWEKAEDNGNRLMYYTLEVRKSISNDSRDQSLRWTA 1797
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+ +S + + ++LK + FR G G +S+ SE+ +
Sbjct 1798 VFNGSCSSICTWRS-KNLK--GTFQFRAVASNAIGFGEYSEISEDIT 1841
Score = 42.2 bits (97), Expect = 0.029, Method: Composition-based stats.
Identities = 28/119 (24%), Positives = 41/119 (34%), Gaps = 17/119 (14%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQL-------PVDVQNGFIRNYTIFYRTII-GNETAVNV 570
P V G EA+++W P QN Y + + T V +
Sbjct 567 PGHPQEVSVL-FGSREALIQWKPPILAIGASPSAWQNWT---YEVKVSSQDILETTQVFL 622
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAF 629
+ S T + L S T YMV + A + +G GP P + A P +A
Sbjct 623 NISRTVLNVPKLQSSTKYMVSVRASSPKG--PGPWSE---PSVGTTLVPATEPPFIMAV 676
>sp|P54754|EPHB3_MOUSE Ephrin type-B receptor 3 OS=Mus musculus
OX=10090 GN=Ephb3 PE=1 SV=2
Length=993
Score = 96.8 bits (239), Expect = 4e-19, Method: Composition-based stats.
Identities = 47/224 (21%), Positives = 76/224 (34%), Gaps = 28/224 (13%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATH-----KFADCKA 174
P P+ + VNE + EW GGR+ L K ++ + C
Sbjct 331 VPSPPRGVISNVNE-TSLILEWSEPRDLGGRDDLLYNVICKKCRGSSGAGGPATCSRCDD 389
Query 175 K-RDTPTSCTVDYSTVY------FVNIEVWVEAENAL-GKVTSDHINFDP-VYKVKPNPP 225
P + V+ V+A N + GK + + P
Sbjct 390 NVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPS 449
Query 226 HNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
++ S L L+W P + +IL Y ++Y K S + S ++S
Sbjct 450 EVPTLHLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSKGIASTV-----TSQKNSVQ 504
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
+ L+P YV ++R G G + S A T +R S A
Sbjct 505 LDGLQPDARYVVQVRARTVAGYGQY---SHPAEFETTSERGSGA 545
Score = 91.1 bits (224), Expect = 2e-17, Method: Composition-based stats.
Identities = 53/291 (18%), Positives = 93/291 (32%), Gaps = 37/291 (13%)
Query 386 KLTVNLTNDRYLATLTV-RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
N A++ N ++D+ + P + + + L +EW+
Sbjct 295 PCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPS--PPRGVISNVNETSLILEWS 352
Query 445 TPRESVKKYILEWCVL----------------SDKAPCITDWQQEDGTVHRTYLRGNLAE 488
PR+ + L + V+ S + ++ G R +L
Sbjct 353 EPRDLGGRDDLLYNVICKKCRGSSGAGGPATCSRCDDNVEFVPRQLGLTERRVHISHLLA 412
Query 489 SKCYLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLP 543
Y V V SP + QA PS+ PT+ + L W P
Sbjct 413 HTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLHLHSSSGSSLTLSW--AP 470
Query 544 VDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ NG I +Y + Y A V S L L D Y+V++ A T G
Sbjct 471 PERPNGVILDYEMKYFEK-SKGIASTVTSQKNSVQLDGLQPDARYVVQVRARTVAGYGQY 529
Query 604 P---EFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGV-------LFCFNKR 644
EF T+ + + + +P+ + + + + L C K+
Sbjct 530 SHPAEFETTSERGSGAQQLQEQLPLIVGSTVAGFVFMVVVVVIALVCLRKQ 580
Score = 68.0 bits (164), Expect = 3e-10, Method: Composition-based stats.
Identities = 45/249 (18%), Positives = 76/249 (31%), Gaps = 30/249 (12%)
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI-KSVIILKYNIQ 260
N + SD + D P+PP + S + L L W+ P L YN+
Sbjct 314 NNFYRADSD--SADSACTTVPSPPRGV---ISNVNETSLILEWSEPRDLGGRDDLLYNVI 368
Query 261 YRTKDAST-------------WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE-DG 306
+ S+ + P T + L T Y F ++ + G
Sbjct 369 CKKCRGSSGAGGPATCSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSG 428
Query 307 KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
K + T + PS+ P+ + W PP NG ILDY
Sbjct 429 KSPLPPRYAAVNITTNQAAPSEVPTLHLHSSSGSSLTL-----SW--APPERPNGVILDY 481
Query 367 EVTLTRWKSHLQNYTV---NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA 423
E+ + + N+ +L + RY+ + R + G + +
Sbjct 482 EMKYFEKSKGIASTVTSQKNSVQLDGLQPDARYVVQVRARTVAGYGQYSHPAEFETTSER 541
Query 424 THPVMDLKA 432
L+
Sbjct 542 GSGAQQLQE 550
>sp|Q64632|ITB4_RAT Integrin beta-4 OS=Rattus norvegicus OX=10116
GN=Itgb4 PE=1 SV=1
Length=1807
Score = 97.2 bits (240), Expect = 4e-19, Method: Composition-based stats.
Identities = 75/541 (14%), Positives = 150/541 (28%), Gaps = 79/541 (15%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
P+N + +K+ W + +K W D+
Sbjct 1130 GAPQNPNAKAAGSRKIHFNWLP--PPGKPMGYRVKY-WVQGDSESEAHLLDSKVPSVELT 1186
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ + + E+ V A A G+ + ++ P+ P L+ + S++ +L+W
Sbjct 1187 NLYPYCDYEMKVCAYGAHGEGPYSSLVSCRTHQEVPSEPGRLA--FNVVSSTVTQLSWAE 1244
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDT---ASTRSSFTVQDLKPFTEYVFRIRCMK 303
P+ + I Y + Y + P + +++L+ Y + ++
Sbjct 1245 PAETNGEITAYEVCYGLVNEDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARN 1304
Query 304 EDGKGYWSDWSEEASGI----TYEDRPSKAPSFWYKIDPSHTQGY--RTVQLVWKTLPPF 357
G W E I T RP P G + +
Sbjct 1305 GAG------WGPEREAIINLATQPKRPMSIPIIPDIPIVDAQGGEDYENFLMYSDDVLRS 1358
Query 358 EANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG---------- 407
A+ + S + VN + L +T N+
Sbjct 1359 PASSQ--------RPSVSDDTEHLVNGRMDFAYPGSANSLHRMTAANVAYGTHLSPHQTH 1410
Query 408 --KSDAAVLT------IPACDFQATHPVMDLKAFPKDNMLWVE--WTTPRESVKKYILEW 457
S ++ LT Q+ D + + W R + L W
Sbjct 1411 RMLSTSSTLTRDYHSLTRTDHSQSGTLPRDYSTLTSLSSQGLPPIWEDGRSRLP---LSW 1467
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
+ S + G+ L G + S + A
Sbjct 1468 TLGSWSRAQMKGVPASRGSPDSIIL-------------------AGQSAAPSWGTDSRGA 1508
Query 518 --PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN--VDSS 573
P + +G + W + D + Y++ Y+ + G E +
Sbjct 1509 MGVPDTPTRLVFSALGPTSLKVSWQEPQCDRA---LLGYSVEYQLLNGGEMHRLNIPNPG 1565
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTT 633
T + L + Y+ R+ A + EG G E +Q ++ + P+ + +
Sbjct 1566 QTSVVVEDLLPNHSYVFRVRAQSQEGW--GREREGVITIESQVHPQSPLCPLPGSAFTLS 1623
Query 634 L 634
Sbjct 1624 T 1624
Score = 96.8 bits (239), Expect = 5e-19, Method: Composition-based stats.
Identities = 41/243 (17%), Positives = 72/243 (30%), Gaps = 26/243 (11%)
Query 386 KLTVNLTNDRYLATL----TVRNLVGKSDAAVLTIPACDFQATH-------PVMDLKAFP 434
+ V L+N ++ A L T ++G+ D ++ + + A
Sbjct 1080 RFQVQLSNPKFGARLGQPNTATVIIGEQDETDRSLINEISASPPLPRGDLGAPQNPNAKA 1139
Query 435 KDNM-LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
+ + W P Y +++ V D + +V T NL Y
Sbjct 1140 AGSRKIHFNWLPPPGKPMGYRVKYWVQGDSESEAHLLDSKVPSVELT----NLYPYCDYE 1195
Query 494 ITVTPVYADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
+ V A G G + Q PS+ + V L W + NG I
Sbjct 1196 MKVCAYGAHGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAE--PAETNGEIT 1253
Query 553 NYTIFY-------RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
Y + Y R I + + + + + +L Y + A G E
Sbjct 1254 AYEVCYGLVNEDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPERE 1313
Query 606 FTF 608
Sbjct 1314 AII 1316
Score = 96.5 bits (238), Expect = 8e-19, Method: Composition-based stats.
Identities = 47/301 (16%), Positives = 89/301 (30%), Gaps = 40/301 (13%)
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA 411
+ LPP +G+ + L+ + + + LA + G
Sbjct 1450 QGLPPIWEDGR---SRLPLSWTLGSWSRAQMKGVPASRGSPDSIILAGQSAAPSWGTDSR 1506
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR--ESVKKYILEWCVLSDKAPCITD 469
+ +P P + + L V W P+ ++ Y +E+ +L+
Sbjct 1507 GAMGVPDT------PTRLVFSALGPTSLKVSWQEPQCDRALLGYSVEYQLLNGGE---MH 1557
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG-------------------SPESI 510
+ + +L + Y+ V +G G P
Sbjct 1558 RLNIPNPGQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPG 1617
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG----NET 566
A+ P + GP + + + L W+ NG I Y + G
Sbjct 1618 SAFTLSTPSAPGP-LVFTALSPDSLQLSWE--RPRRPNGDILGYLVTCEMAQGGGPARTF 1674
Query 567 AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVC 626
V+ D+ + T+ L+ + Y ++ A T EG E T G +
Sbjct 1675 RVDGDNPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSHSG 1734
Query 627 L 627
L
Sbjct 1735 L 1735
Score = 88.4 bits (217), Expect = 2e-16, Method: Composition-based stats.
Identities = 61/305 (20%), Positives = 107/305 (35%), Gaps = 58/305 (19%)
Query 146 WDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
W+ GR + L ++TL W+ + A R +P S + + A + G
Sbjct 1456 WEDGR-SRLPLSWTL-GSWSRAQMKGVPASRGSPDSIILAGQS-----------AAPSWG 1502
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD 265
+ + P+ P L + LK++W P +L Y+++Y+ +
Sbjct 1503 TDSRGAMGV-------PDTPTRLVFSALG--PTSLKVSWQEP-QCDRALLGYSVEYQLLN 1552
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG--------------YWS 311
++ + ++S V+DL P YVFR+R ++G G S
Sbjct 1553 GGEMHRLNIPN--PGQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQS 1610
Query 312 DWSE-EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S T + P + + P ++QL W+ P NG IL Y VT
Sbjct 1611 PLCPLPGSAFTLSTPSAPGPLVFTALSPD------SLQLSWE--RPRRPNGDILGYLVTC 1662
Query 371 TRWKSHLQNYTV------NATKLTVNLTND--RYLATLTVRNLVGKSD--AAVLTIPACD 420
+ T ++LTV ++ Y + R G ++TI + D
Sbjct 1663 EMAQGGGPARTFRVDGDNPESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQD 1722
Query 421 FQATH 425
Sbjct 1723 GGPFP 1727
Score = 74.5 bits (181), Expect = 4e-12, Method: Composition-based stats.
Identities = 44/207 (21%), Positives = 72/207 (35%), Gaps = 29/207 (14%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPE 275
P+ + P N + + S + W P + Y ++Y + S+
Sbjct 1123 PLPRGDLGAPQNPNAKAAG--SRKIHFNWLPP---PGKPMGYRVKYWVQGD---SESEAH 1174
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
S S + +L P+ +Y ++ G+G +S S T+++ PS+ +
Sbjct 1175 LLDSKVPSVELTNLYPYCDYEMKVCAYGAHGEGPYSS---LVSCRTHQEVPSEPGRLAFN 1231
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV----------TLTRWKSHLQNYTVNAT 385
+ S QL W P E NG+I YEV + K L + N
Sbjct 1232 VVSSTVT-----QLSWAE--PAETNGEITAYEVCYGLVNEDNRPIGPMKKVLVDNPKNRM 1284
Query 386 KLTVNLTN-DRYLATLTVRNLVGKSDA 411
L NL Y T+ RN G
Sbjct 1285 LLIENLRESQPYRYTVKARNGAGWGPE 1311
Score = 73.4 bits (178), Expect = 8e-12, Method: Composition-based stats.
Identities = 35/221 (16%), Positives = 66/221 (30%), Gaps = 22/221 (10%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA-THKFADCKAKRDTPTSCT 183
P+ P L ++ W + ++++ + + TS
Sbjct 1511 VPDTPTRLVFSALGPTSLKVSWQEPQCDRALLGYSVEYQLLNGGEMHRLNIPNPGQTSVV 1570
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPP--------HNLS------ 229
V+ + + V A++ G +V P P LS
Sbjct 1571 VE-DLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAFTLSTPSAPG 1629
Query 230 -VINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
++ + L+L+W P + IL Y + ++ D + S TV
Sbjct 1630 PLVFTALSPDSLQLSWERPRRPNGDILGYLVTCEMAQGGGPARTFRVDGDNPESRLTVPG 1689
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
L Y F+++ +G G E IT E +
Sbjct 1690 LSENVPYKFKVQARTTEGFGP-----EREGIITIESQDGGP 1725
>sp|Q07497|EPHB5_CHICK Ephrin type-B receptor 5 OS=Gallus gallus
OX=9031 GN=EPHB5 PE=2 SV=1
Length=1002
Score = 96.8 bits (239), Expect = 5e-19, Method: Composition-based stats.
Identities = 41/204 (20%), Positives = 74/204 (36%), Gaps = 25/204 (12%)
Query 126 PEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWAT-HKFADC------K 173
P P++LS + G + W GGR+ + + C +
Sbjct 342 PSAPRDLSYEIV-GSNVLLTWRLPKDLGGRKDVFFNVICKECPTRSAGTCVRCGDNVQFE 400
Query 174 AKRDTPTSCTVDYSTVY-FVNIEVWVEAENALGKVTSD-----HINFDPVYKVKPNPPHN 227
++ T V S + V ++A N + +++S+ IN V P
Sbjct 401 PRQVGLTESRVQVSNLLARVQYTFEIQAVNLVTELSSEAPQYATINVSTSQSVPSAIPM- 459
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
+ +S + L+W P + +IL Y ++Y K + S + T+
Sbjct 460 --MHQVSRATSSITLSWPQPDQPNGVILDYQLRYFDKAEDEDNSFT---LTSETNMATIL 514
Query 288 DLKPFTEYVFRIRCMKEDGKGYWS 311
+L P YVF++R G G +S
Sbjct 515 NLSPGKIYVFQVRARTAVGYGPYS 538
Score = 88.4 bits (217), Expect = 2e-16, Method: Composition-based stats.
Identities = 41/235 (17%), Positives = 74/235 (31%), Gaps = 27/235 (11%)
Query 424 THPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCIT------------DWQ 471
DL + + + W P++ + + + V+ + P +
Sbjct 342 PSAPRDLSYEIVGSNVLLTWRLPKDLGGRKDVFFNVICKECPTRSAGTCVRCGDNVQFEP 401
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-----SIKAYLKQAPPSKGPTVR 526
++ G NL Y + V S E +I Q+ PS P +
Sbjct 402 RQVGLTESRVQVSNLLARVQYTFEIQAVNLVTELSSEAPQYATINVSTSQSVPSAIPMMH 461
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET-AVNVDSSHTEYTLSSLTSD 585
+ L W Q D NG I +Y + Y +E + + S T+ +L+
Sbjct 462 QVSRATSSITLSWPQ--PDQPNGVILDYQLRYFDKAEDEDNSFTLTSETNMATILNLSPG 519
Query 586 TLYMVRMAAYTDEGGKD-GPEFTFTTP------KFAQGEIEAIVVPVCLAFLLTT 633
+Y+ ++ A T G + F T + AQ + IV
Sbjct 520 KIYVFQVRARTAVGYGPYSGKMYFQTLMAGEHSEMAQDRLPLIVGSALGGLAFLV 574
Score = 59.1 bits (141), Expect = 2e-07, Method: Composition-based stats.
Identities = 42/222 (19%), Positives = 75/222 (34%), Gaps = 28/222 (13%)
Query 208 TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDA 266
S N D P+ P +LS E + S + LTW P + + +N+ +
Sbjct 328 RSASDNSDAPCTGIPSAPRDLS---YEIVGSNVLLTWRLPKDLGGRKDVFFNVICKECPT 384
Query 267 STWSQ---------IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
+ P T S V +L +Y F I+ + + S+ + A
Sbjct 385 RSAGTCVRCGDNVQFEPRQVGLTESRVQVSNLLARVQYTFEIQAVNLVTE-LSSEAPQYA 443
Query 318 SG--ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
+ T + PS P + ++ ++ L W P + NG ILDY++
Sbjct 444 TINVSTSQSVPSAIP-----MMHQVSRATSSITLSW--PQPDQPNGVILDYQLRYFDKAE 496
Query 376 HLQNYTVNATKLTV-----NLTNDRYLATLTVRNLVGKSDAA 412
N ++ + Y+ + R VG +
Sbjct 497 DEDNSFTLTSETNMATILNLSPGKIYVFQVRARTAVGYGPYS 538
>sp|P08922|ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS
OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3
Length=2347
Score = 97.2 bits (240), Expect = 5e-19, Method: Composition-based stats.
Identities = 41/222 (18%), Positives = 71/222 (32%), Gaps = 13/222 (6%)
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAP 465
VG S A A P + + + + W + S KYI++W A
Sbjct 82 VGCSSAEGAYEEEVLENADLPTAPFASSIGSHNMTLRWKSANFSGVKYIIQWKY----AQ 137
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADG---PGSPESIKAYLKQAPPSKG 522
+ W +Y+ L Y+ V ++ P P
Sbjct 138 LLGSWTYTKTVSRPSYVVKPLHPFTEYIFRVVWIFTAQLQLYSPPSPSYRTHPHGVPETA 197
Query 523 PTVR-TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS 581
P +R + + + WD P G I Y + +I ++ + T + S
Sbjct 198 PLIRNIESSSPDTVEVSWD--PPQFPGGPILGYNL---RLISKNQKLDAGTQRTSFQFYS 252
Query 582 LTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
+T+Y +AA + G E + TT A + E +
Sbjct 253 TLPNTIYRFSIAAVNEVGEGPEAESSITTSSSAVQQEEQWLF 294
Score = 86.8 bits (213), Expect = 7e-16, Method: Composition-based stats.
Identities = 44/190 (23%), Positives = 67/190 (35%), Gaps = 16/190 (8%)
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDA-STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
L W + + V KY IQ++ +W+ +R S+ V+ L PFTEY+FR+
Sbjct 116 TLRWKSANFSGV---KYIIQWKYAQLLGSWTYTK----TVSRPSYVVKPLHPFTEYIFRV 168
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
+ +S S P P I + TV++ W PP
Sbjct 169 VWIFTAQLQLYSPPSPSYRTH-----PHGVPETAPLIRNIESSSPDTVEVSWD--PPQFP 221
Query 360 NGKILDYEVTLTRWKSHLQNYTVNAT-KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
G IL Y + L L T + + L N Y ++ N VG+ A +I
Sbjct 222 GGPILGYNLRLISKNQKLDAGTQRTSFQFYSTLPNTIYRFSIAAVNEVGEGPEAESSITT 281
Query 419 CDFQATHPVM 428
Sbjct 282 SSSAVQQEEQ 291
Score = 83.8 bits (205), Expect = 6e-15, Method: Composition-based stats.
Identities = 69/434 (16%), Positives = 135/434 (31%), Gaps = 54/434 (12%)
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
LTW + + L Y + + S S + S ++DL+PF+ Y+ +I
Sbjct 1475 LTWYGITSPTPTYLVYYAEVNDRKNS--SDLKYRILEFQDSIALIEDLQPFSTYMIQIAV 1532
Query 302 MKEDGKGYWSDWSE------EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLP 355
Y+SD E E G T P ++ + + ++ + W+
Sbjct 1533 KN-----YYSDPLEHLPPGKEIWGKTKNGVPEA-----VQLINTTVRSDTSLIISWRES- 1581
Query 356 PFEANGKI--LDYEVTLT------RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG 407
+ NG + Y++ ++ + L V + + L V
Sbjct 1582 -HKPNGPKESVRYQLAISHLALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLKVLACHS 1640
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
+ + P P P++ L W P I W L
Sbjct 1641 EEMWCTESHPVTVEMFNTPEKPYSLVPENTSLQFNWKAPLN--VNLIRFWVELQKWKYNE 1698
Query 468 TDWQQEDGTVHRTYL--RGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPT 524
+ + Y+ NL Y + V VY G S +++ K P+K
Sbjct 1699 FYHVKTSCSQGPAYVCNITNLQPYTSYNVRVVVVYKTGENSTSLPESFKTKAGVPNKPGI 1758
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGF-IRNYTIFYRTIIGNET-------AVNVDSSHTE 576
+ + KN +W+ NG I Y + R N + + S +
Sbjct 1759 PKLLEGSKNSI--QWE---KAEDNGCRITYYILEIRKSTSNNLQNQNLRWKMTFNGSCSS 1813
Query 577 ---YTLSSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIE--AIVVPVCLAFL 630
+ +L ++ R+ A + G + I + ++ + +
Sbjct 1814 VCTWKSKNLKG--IFQFRVVAANNLGFGEYSGISENIILVGDDFWIPETSFILTIIVGIF 1871
Query 631 LTTLLGVLFCFNKR 644
L + + F +++R
Sbjct 1872 LVVTIPLTFVWHRR 1885
Score = 78.0 bits (190), Expect = 4e-13, Method: Composition-based stats.
Identities = 45/271 (17%), Positives = 84/271 (31%), Gaps = 42/271 (15%)
Query 348 QLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG 407
+L W I + + T+ + +V L N + +++ L G
Sbjct 894 RLFW-----------INGFRIITTQEIGQKTSVSV----LEPARFNQFTIIQTSLKPLPG 938
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
IP ++ + + + W P ++W V+
Sbjct 939 NFSFTPKVIPDSVQES-----SFRIEGNASSFQILWNGPPA------VDWGVVFYSVEFS 987
Query 468 TDWQQEDGTVHR--TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
+ H + L + ++VTP G G S+ + PS
Sbjct 988 AHSKFLASEQHSLPVFTVEGLEPYALFNLSVTPYTYWGKGPKTSLSLRAPETVPSAPENP 1047
Query 526 RTKKVG------KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG--------NETAVNVD 571
R + KNE V+E+ +NG + + IFY + AVNV
Sbjct 1048 RIFILPSGKCCNKNEVVVEFRWNKPKHENGVLTKFEIFYNISNQSITNKTCEDWIAVNVT 1107
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
S + L ++ ++ A+T +G
Sbjct 1108 PSVMSFQLEGMSPRCFIAFQVRAFTSKGPGP 1138
Score = 67.2 bits (162), Expect = 7e-10, Method: Composition-based stats.
Identities = 45/251 (18%), Positives = 79/251 (31%), Gaps = 30/251 (12%)
Query 101 LTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL 160
+ C+ E+ + + P P M W + + +
Sbjct 82 VGCSSAEGAYEEEVLENADL-----PTAPF---ASSIGSHNMTLRWKSANFSG--VKYII 131
Query 161 KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE-AENALGKVTSDHINFDPVYK 219
+ ++A + K V F V A ++ S P Y+
Sbjct 132 QWKYAQLLGSWTYTKT-VSRPSYVVKPLHPFTEYIFRVVWIFTAQLQLYSPP---SPSYR 187
Query 220 VKPN--PPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPED 276
P+ P + N E S ++++W P IL YN++ +K+ D
Sbjct 188 THPHGVPETAPLIRNIESSSPDTVEVSWDPPQFPGGPILGYNLRLISKNQKL-------D 240
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ R+SF P T Y F I + E G+G E S IT + W +
Sbjct 241 AGTQRTSFQFYSTLPNTIYRFSIAAVNEVGEGP-----EAESSITTSSSAVQQEEQWLFL 295
Query 337 DPSHTQGYRTV 347
+ R++
Sbjct 296 SRKTSLRKRSL 306
Score = 66.0 bits (159), Expect = 2e-09, Method: Composition-based stats.
Identities = 40/312 (13%), Positives = 102/312 (33%), Gaps = 44/312 (14%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLE---TNFTLKSEWATHKFADCKAKRDTPTS 181
PE + ++ V + W + + + L + ++ +
Sbjct 1557 VPEAVQLINTTVRSDTSLIISWRESHKPNGPKESVRYQLAISHLA-LIPETPLRQSEFPN 1615
Query 182 CTVDYSTVYFVN---IEVWVEAENA--LGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
+ + V A ++ + S + + P P++L
Sbjct 1616 GRLTLLVTRLSGGNIYVLKVLACHSEEMWCTESHPVTVEMFNT--PEKPYSLV-----PE 1668
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
++ L+ W P +V ++++ ++ + + + + + + +L+P+T Y
Sbjct 1669 NTSLQFNWKAPL--NVNLIRFWVELQKWKYNEFYHVKTSCSQGPAYVCNITNLQPYTSYN 1726
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
R+ + + G+ S S T P+K P +G + + W+
Sbjct 1727 VRVVVVYKTGENS---TSLPESFKTKAGVPNKP------GIPKLLEGSKN-SIQWE---K 1773
Query 357 FEANG-KILDYEVTLTRWKSHL-------QNYTVNATKLTV-----NLTNDRYLATLTVR 403
E NG +I Y + + + S+ T N + +V + +
Sbjct 1774 AEDNGCRITYYILEIRKSTSNNLQNQNLRWKMTFNGSCSSVCTWKSKNLKGIFQFRVVAA 1833
Query 404 NLVGKSDAAVLT 415
N +G + + ++
Sbjct 1834 NNLGFGEYSGIS 1845
Score = 57.2 bits (136), Expect = 7e-07, Method: Composition-based stats.
Identities = 23/173 (13%), Positives = 51/173 (29%), Gaps = 17/173 (10%)
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY--LITV 496
+ W Y++ + ++D+ + L +L Y I V
Sbjct 1473 TNLTWYGITSPTPTYLVYYAEVNDRKNSSDLKYRILEFQDSIALIEDLQPFSTYMIQIAV 1532
Query 497 TPVYADGPGSPES---IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
Y+D I K P + T ++ W + NG
Sbjct 1533 KNYYSDPLEHLPPGKEIWGKTKNGVPEAVQLINTTVRSDTSLIISWRE--SHKPNGPKE- 1589
Query 554 YTIFYRTIIGNETAVN--------VDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
++ Y+ I + + + ++ L+ +Y++++ A E
Sbjct 1590 -SVRYQLAISHLALIPETPLRQSEFPNGRLTLLVTRLSGGNIYVLKVLACHSE 1641
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 39/273 (14%), Positives = 81/273 (30%), Gaps = 27/273 (10%)
Query 66 VWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLP 125
++ N F I Q + S + I T G I
Sbjct 895 LFWINGFRIITTQEIGQKTSVSVLEPARFNQFTIIQTSLKPLPGNFSFTPKVI------- 947
Query 126 PEKPKNLSCIV-NEGKKMRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
P+ + S + + W+ ++++ + A + T
Sbjct 948 PDSVQESSFRIEGNASSFQILWNGPPAVDWGVVFYSVEFSAHSKFLASEQHSLPVFTVEG 1007
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI---- 239
++ ++ ++ V GK ++ V P+ P N +
Sbjct 1008 LEPYALFNLS----VTPYTYWGKGPKTSLSLRAPETV-PSAPENPRIFILPSGKCCNKNE 1062
Query 240 --LKLTWTNPSIKSVIILKYNIQYRTKDAS----TWSQIPPEDTASTRSSFTVQDLKPFT 293
++ W P ++ ++ K+ I Y + S T + + SF ++ + P
Sbjct 1063 VVVEFRWNKPKHENGVLTKFEIFYNISNQSITNKTCEDWIAVNVTPSVMSFQLEGMSPRC 1122
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
F++R G G ++D T E P
Sbjct 1123 FIAFQVRAFTSKGPGPYADV---VKSTTSEINP 1152
Score = 53.7 bits (127), Expect = 9e-06, Method: Composition-based stats.
Identities = 27/134 (20%), Positives = 48/134 (36%), Gaps = 22/134 (16%)
Query 212 INFDPVYKVKPNP--PHNLSVINSEELSSILKLTWTNPSIK---SVIILKYNIQYRTKDA 266
+ F ++ P P P LSV+ S + W P++ +VI++ I+
Sbjct 546 VIFGSSSQLHPLPGRPQELSVLF---GSHQALVQWKPPALAIGANVILISDIIELFELGP 602
Query 267 STWSQIPPEDTASTR--------------SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
S W E ST+ + V +L+ +Y +R G WS+
Sbjct 603 SAWQNWTYEVKVSTQDPPEVTHIFLNISGTMLNVPELQSAMKYKVSVRASSPKRPGPWSE 662
Query 313 WSEEASGITYEDRP 326
S + + + P
Sbjct 663 PSVGTTLVPASEPP 676
>sp|P29317|EPHA2_HUMAN Ephrin type-A receptor 2 OS=Homo sapiens
OX=9606 GN=EPHA2 PE=1 SV=2
Length=976
Score = 96.5 bits (238), Expect = 6e-19, Method: Composition-based stats.
Identities = 64/346 (18%), Positives = 112/346 (32%), Gaps = 42/346 (12%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV-----LSDKAPC-----ITDWQQ 472
L A + + WT P++S + + + V + C + +
Sbjct 328 PPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCEASVRYSE 387
Query 473 EDGTVHRT-YLRGNLAESKCYLITVTPVYA-DGPGSPESIKAYLKQAPPSKGPTVRTKKV 530
+ RT +L Y TV G + S + ++ P VR +
Sbjct 388 PPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSFRTASVSINQTEPPKVRLEGR 447
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMV 590
+ W P Q + Y + YR + + + TL L DT Y+V
Sbjct 448 STTSLSVSWSIPPP--QQSRVWKYEVTYRKKGDSNSYNVRRTEGFSVTLDDLAPDTTYLV 505
Query 591 RMAAYTDEGGKDGP---EFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLI 647
++ A T EG G EF +P+ + V V + LL F +R
Sbjct 506 QVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGGVAVGVVLLLVLAGVGFFIHRRRKNQ 565
Query 648 KKHIWPNVPDPSKSHIAQWSP--HTPPRHNFNSKDQ------------------MYSDGN 687
+ P D S Q P H + +Q + G
Sbjct 566 RARQSPE--DVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGE 623
Query 688 FTDVSVVEIEAND-KKPFPEDLKSLDL--FKKEKINTEGHSSGIGG 730
F +V ++ + KK P +K+L +K++++ G + +G
Sbjct 624 FGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQ 669
Score = 95.3 bits (235), Expect = 1e-18, Method: Composition-based stats.
Identities = 48/202 (24%), Positives = 83/202 (41%), Gaps = 23/202 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDG-----GRETHLETNFTLKSEWATHKFADCKAK---R 176
PP P L+ + K + W GRE + + + + + C+A
Sbjct 328 PPSAPHYLTAVGMGAK-VELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCEASVRYS 386
Query 177 DTPTSCTVDYSTVY----FVNIEVWVEAENAL-GKVTSDHINFDPVYKVKPNPPHNLSVI 231
+ P T TV +N VEA N + G VTS V + PP V
Sbjct 387 EPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSFRTASVSINQTEPP---KVR 443
Query 232 NSEELSSILKLTWTNPSIKSVIILKYNIQYRTK-DASTWSQIPPEDTASTRSSFTVQDLK 290
++ L ++W+ P + + KY + YR K D+++++ E S T+ DL
Sbjct 444 LEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSNSYNVRRTEGF-----SVTLDDLA 498
Query 291 PFTEYVFRIRCMKEDGKGYWSD 312
P T Y+ +++ + ++G+G S
Sbjct 499 PDTTYLVQVQALTQEGQGAGSK 520
Score = 62.2 bits (149), Expect = 2e-08, Method: Composition-based stats.
Identities = 41/213 (19%), Positives = 72/213 (34%), Gaps = 27/213 (13%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNI----------QYRT 263
DP PP + + + + ++L WT P + Y++ +
Sbjct 319 DPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCWPESGECGP 378
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+AS PP TR+S TV DL+P Y F + S AS +
Sbjct 379 CEASVRYSEPPHGL--TRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSFRTASVSINQ 436
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN 383
P K +++ T ++ + W PP ++ ++ YEVT +
Sbjct 437 TEPPK-----VRLEGRSTT---SLSVSWSIPPPQQS--RVWKYEVTYRKKGDSNSYNVRR 486
Query 384 ATKLTVNL----TNDRYLATLTVRNLVGKSDAA 412
+V L + YL + G+ +
Sbjct 487 TEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGS 519
>sp|P13591|NCAM1_HUMAN Neural cell adhesion molecule 1 OS=Homo
sapiens OX=9606 GN=NCAM1 PE=1 SV=3
Length=858
Score = 96.1 bits (237), Expect = 6e-19, Method: Composition-based stats.
Identities = 72/431 (17%), Positives = 125/431 (29%), Gaps = 63/431 (15%)
Query 44 FTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQY--------------TIINRTASSV 89
T C + I W+T+ I E+ ++ R+ + V
Sbjct 325 VTLTC-------EASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARV 377
Query 90 TFTDIASLNIQLTCNILT-----FGQLEQNVYGITIISGLPPE--KPKNLSCIVNEGKKM 142
+ + S+ + GQ Q++Y + P+ P + +
Sbjct 378 SSLTLKSIQYTDAGEYICTASNTIGQDSQSMY---LEVQYAPKLQGPVAVYTWEGNQVNI 434
Query 143 RCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN 202
C E + T+ Y+T +EV ++EN
Sbjct 435 TC------EVFAYPSATISWFRDGQLLPSSNYSN------IKIYNTPSASYLEVTPDSEN 482
Query 203 ALGKVTSDHINFDPVYK-----VKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILK 256
G +N V+ + P + S+ E SS ++ + P ILK
Sbjct 483 DFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILK 542
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSS-FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y ++R W + ++ T+ LKP T Y R+ + G G S SE
Sbjct 543 YKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASE 602
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT---- 371
+ + PS AP ++ + + I Y V
Sbjct 603 FKT-QPVQGEPS-APKLEGQMGEDGNSIKVNLI------KQDDGGSPIRHYLVRYRALSS 654
Query 372 RWKSHLQNYTVNATKLTVNLT-NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
WK ++ + + + +L N Y + N GKS AA P
Sbjct 655 EWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGS 714
Query 431 KAFPKDNMLWV 441
V
Sbjct 715 PTSGLSTGAIV 725
Score = 84.9 bits (208), Expect = 2e-15, Method: Composition-based stats.
Identities = 40/248 (16%), Positives = 85/248 (34%), Gaps = 10/248 (4%)
Query 386 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT 445
++T + ND T N +G+ + + A + + P + V++
Sbjct 475 EVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSID---QVEPYSSTAQVQFDE 531
Query 446 PRE----SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
P + KY EW + ++ + ++ ++ L Y + + +
Sbjct 532 PEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNG 591
Query 502 DGPGSPESIKAYLKQAPPSKGPTVRTK-KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G G + + Q + + + ++G++ ++ + + D IR+Y + YR
Sbjct 592 KGLGEISAASEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRA 651
Query 561 IIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE 619
+ + + S L SL + Y V + A +G F F T I
Sbjct 652 LSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRT-SAQPTAIP 710
Query 620 AIVVPVCL 627
A P
Sbjct 711 ANGSPTSG 718
>sp|P79108|GHR_BOSIN Growth hormone receptor OS=Bos indicus OX=9915
GN=GHR PE=2 SV=1
Length=634
Score = 95.7 bits (236), Expect = 7e-19, Method: Composition-based stats.
Identities = 39/199 (20%), Positives = 75/199 (38%), Gaps = 23/199 (12%)
Query 129 PKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEW---ATHKFADCKAK-RDTPTSCTV 184
PK C E + C W G L++ +++ + ++ +C SC
Sbjct 51 PKFTKCRSPELETFSCHWTDGANHSLQSPGSVQMFYIRRDIQEWKECPDYVSAGENSCYF 110
Query 185 DYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK-- 241
+ S T + + + + + DH F V+P+PP L+ + +
Sbjct 111 NSSYTSVWTPYCIKLTSNGGI----VDHKCFSVEDIVQPDPPVGLNWTLLNISLTEIHAD 166
Query 242 --LTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+ W P V IIL+Y + Y+ + + W + P +S + L+ EY
Sbjct 167 ILVKWEPPPNTDVKMGWIILEYELHYKELNETQWKMMDPLMV----TSVPMYSLRLDKEY 222
Query 296 VFRIRCMKED--GKGYWSD 312
R+R + + G +S+
Sbjct 223 EVRVRTRQRNTEKYGKFSE 241
Score = 57.6 bits (137), Expect = 4e-07, Method: Composition-based stats.
Identities = 99/511 (19%), Positives = 169/511 (33%), Gaps = 91/511 (18%)
Query 454 ILEW--CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
I EW C A + + T T Y I +T S++
Sbjct 91 IQEWKECPDYVSAGENSCYFNSSYTSVWT----------PYCIKLTSNGGIVDHKCFSVE 140
Query 512 AYLKQAPPSKGPTVRTKKVGKNEA----VLEWDQLP-VDVQNG-FIRNYTIFYRTIIGNE 565
++ PP G + E +++W+ P DV+ G I Y + Y+ + +
Sbjct 141 DIVQPDPP-VGLNWTLLNISLTEIHADILVKWEPPPNTDVKMGWIILEYELHYKELNETQ 199
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAY---TDEGGKDGPEFTFTTPKFAQGEIEA-I 621
+ T + SL D Y VR+ T++ GK T P+ E
Sbjct 200 WKMMDPLMVTSVPMYSLRLDKEYEVRVRTRQRNTEKYGKFSEVLLITFPQMNPSACEEDF 259
Query 622 VVPVCL----AFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF- 676
P L L + L F+K+ IK I P VP P I P
Sbjct 260 QFPWFLIIMFGILGLAVTLFLLIFSKQQRIKMLILPPVPVP---KIKGIDPDLLKEGKLE 316
Query 677 ----------NSKDQMYSDGNFTDVSVVEIEANDKKPFPEDL---------KSLDLF--- 714
N K + Y+D ++ + ++I+ D+K D KSL++F
Sbjct 317 EVNTILAIHDNYKHEFYNDDSWVEFIELDIDDPDEKTEGSDTDRLLSNDHEKSLNIFGAK 376
Query 715 ----------KKEKINTEGHSSGI--GGSSCMSSSR-------PSISSSDENESSQNTSS 755
+ + + + H S + G S R + ++N S N ++
Sbjct 377 DDDSGRTSCYEPDILEADFHVSDMCDGTSEVAQPQRLKGEADISCLDQKNQNNSPSNDAA 436
Query 756 TV-QYSTVVHSGYRHQVPSVQVFSRSEST-QPLLDSEERPEDL-------QLVDHVDGGD 806
Q +V+H P + +EST Q + P L Q+ D G+
Sbjct 437 PANQQPSVIH--VEENKPRPLLIGGTESTHQAVHHQLSNPSSLANIDFYAQVSDITPAGN 494
Query 807 GILPRQQYFKQNCSQHESSPDISHFERSKQVS------SVNEEDFVRLKQQI--SDHISQ 858
+L Q K Q ++ P++ ++ + V+ + ++ L + H+
Sbjct 495 VVLSPGQKNKTGNPQCDTHPEVVTSCQANFIVDNAYFCEVDAKKYIALAPHVEAESHVEP 554
Query 859 SCGSGQMKMFQEVSAADAFGPGTEGQVERFE 889
S + + E A GT V E
Sbjct 555 SFNQEDIYITTESLTTTAGRSGTAEHVPSSE 585
>sp|Q63HQ2|EGFLA_HUMAN Pikachurin OS=Homo sapiens OX=9606 GN=EGFLAM
PE=1 SV=2
Length=1017
Score = 95.7 bits (236), Expect = 1e-18, Method: Composition-based stats.
Identities = 30/199 (15%), Positives = 59/199 (30%), Gaps = 15/199 (8%)
Query 421 FQATHPVMDLKAFPKD-NMLWVEWT---TPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
P +D+K + ++W P + Y + + + +
Sbjct 32 PGKVGPPLDIKLGALNCTAFSIQWKMPRHPGSPILGYTVFYSEVGADKSLQEQLHSVPLS 91
Query 477 V---HRTYLRGNLAESKCYLITVTPVYADGPG---SPESIKAYLKQA--PPSKGPTVRTK 528
+ G+L Y +++ G G SP + + + PP+
Sbjct 92 RDIPTTEEVIGDLKPGTEYRVSIAAYSQAGKGRLSSPRHVTTLSQDSCLPPAAPQQPHVI 151
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTI-IGNETAVNVDSSHTEYTLSSLTSDT 586
V +E L W + I+ Y++ F R T+++ + L DT
Sbjct 152 VVSDSEVALSWKPG-ASEGSAPIQYYSVEFIRPDFDKKWTSIHERIQMDSMVIKGLDPDT 210
Query 587 LYMVRMAAYTDEGGKDGPE 605
Y + A G
Sbjct 211 NYQFAVRAMNSHGPSPRSW 229
Score = 90.7 bits (223), Expect = 4e-17, Method: Composition-based stats.
Identities = 40/205 (20%), Positives = 63/205 (31%), Gaps = 17/205 (8%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT----KDASTWSQIPPED 276
K PP ++ + + + W P IL Y + Y K P
Sbjct 34 KVGPPLDIKLGALNC--TAFSIQWKMPRHPGSPILGYTVFYSEVGADKSLQEQLHSVPLS 91
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ + DLKP TEY I + GKG S +T + S P +
Sbjct 92 RDIPTTEEVIGDLKPGTEYRVSIAAYSQAGKGRLSSP----RHVTTLSQDSCLPPAAPQQ 147
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL------TRWKSHLQNYTVNATKLTVN 390
V L WK E + I Y V +W S + +++ +
Sbjct 148 PHVIVVSDSEVALSWKPG-ASEGSAPIQYYSVEFIRPDFDKKWTSIHERIQMDSMVIKGL 206
Query 391 LTNDRYLATLTVRNLVGKSDAAVLT 415
+ Y + N G S + +
Sbjct 207 DPDTNYQFAVRAMNSHGPSPRSWPS 231
Score = 83.8 bits (205), Expect = 4e-15, Method: Composition-based stats.
Identities = 38/212 (18%), Positives = 67/212 (32%), Gaps = 18/212 (8%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWAT------HKFADCKAKRDTP 179
P ++ +W R +T+ + RD P
Sbjct 36 GPPLDIKLGALNCTAFSIQWKMPRHPGSPILGYTVFYSEVGADKSLQEQLHSVPLSRDIP 95
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYK---VKPNPPHNLSVINSEE 235
T+ V V + A + GK S + + + + P P VI +
Sbjct 96 TTEEVIGDLKPGTEYRVSIAAYSQAGKGRLSSPRHVTTLSQDSCLPPAAPQQPHVIVVSD 155
Query 236 LSSILKLTWTNPSIKSV-IILKYNIQY-RTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
S + L+W + + I Y++++ R W+ I S ++ L P T
Sbjct 156 --SEVALSWKPGASEGSAPIQYYSVEFIRPDFDKKWTSIHERI---QMDSMVIKGLDPDT 210
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
Y F +R M G S S+ + E+
Sbjct 211 NYQFAVRAMNSHGPSPRSWPSDIIRTLCPEEA 242
Score = 39.1 bits (89), Expect = 0.25, Method: Composition-based stats.
Identities = 15/91 (16%), Positives = 24/91 (26%), Gaps = 2/91 (2%)
Query 122 SGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADCKAKRDTP 179
S LPP P+ IV ++ W G ++++
Sbjct 138 SCLPPAAPQQPHVIVVSDSEVALSWKPGASEGSAPIQYYSVEFIRPDFDKKWTSIHERIQ 197
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSD 210
V N + V A N+ G
Sbjct 198 MDSMVIKGLDPDTNYQFAVRAMNSHGPSPRS 228
>sp|O46600|GHR_BOVIN Growth hormone receptor OS=Bos taurus OX=9913
GN=GHR PE=2 SV=2
Length=634
Score = 94.9 bits (234), Expect = 1e-18, Method: Composition-based stats.
Identities = 39/199 (20%), Positives = 75/199 (38%), Gaps = 23/199 (12%)
Query 129 PKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEW---ATHKFADCKAK-RDTPTSCTV 184
PK C E + C W G L++ +++ + ++ +C SC
Sbjct 51 PKFTKCRSPELETFSCHWTDGANHSLQSPGSVQMFYIRRDIQEWKECPDYVSAGENSCYF 110
Query 185 DYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK-- 241
+ S T + + + + + DH F V+P+PP L+ + +
Sbjct 111 NSSYTSVWTPYCIKLTSNGGI----VDHKCFSVEDIVQPDPPVGLNWTLLNISLTEIHAD 166
Query 242 --LTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+ W P V IIL+Y + Y+ + + W + P +S + L+ EY
Sbjct 167 ILVKWEPPPNTDVKMGWIILEYELHYKELNETQWKMMDPLMV----TSVPMYSLRLDKEY 222
Query 296 VFRIRCMKED--GKGYWSD 312
R+R + + G +S+
Sbjct 223 EVRVRTRQRNTEKYGKFSE 241
Score = 56.0 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 87/426 (20%), Positives = 138/426 (32%), Gaps = 60/426 (14%)
Query 454 ILEW--CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
I EW C A + + T T Y I +T S++
Sbjct 91 IQEWKECPDYVSAGENSCYFNSSYTSVWT----------PYCIKLTSNGGIVDHKCFSVE 140
Query 512 AYLKQAPPSKGPTVRTKKVGKNEA----VLEWDQLP-VDVQNG-FIRNYTIFYRTIIGNE 565
++ PP G + E +++W+ P DV+ G I Y + Y+ + +
Sbjct 141 DIVQPDPP-VGLNWTLLNISLTEIHADILVKWEPPPNTDVKMGWIILEYELHYKELNETQ 199
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAY---TDEGGKDGPEFTFTTPKFAQGEIEA-I 621
+ T + SL D Y VR+ T++ GK T P+ E
Sbjct 200 WKMMDPLMVTSVPMYSLRLDKEYEVRVRTRQRNTEKYGKFSEVLLITFPQMNPSACEEDF 259
Query 622 VVPVCL----AFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF- 676
P L L + L F+K+ IK I P VP P I P
Sbjct 260 QFPWFLIIIFGILGLAVTLYLLIFSKQQRIKMLILPPVPVP---KIKGIDPDLLKEGKLE 316
Query 677 ----------NSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSS 726
N K + Y+D ++ + ++I+ D+K D L EK + +
Sbjct 317 EVNTILAIHDNYKHEFYNDDSWVEFIELDIDDPDEKTEGSDTDRLLSNDHEK-SLNIFGA 375
Query 727 GIGGSSCMSSSRPSISSSDENESS--QNTSSTVQYSTVVHSG------YRHQVPSVQVFS 778
S S P I +D + S TS Q + ++Q S +
Sbjct 376 KDDDSGRTSCYEPDILEADFHVSDMCDGTSEVAQPQRLKGEADISCLDQKNQNNSPSNDA 435
Query 779 RSESTQP--LLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQ 836
S QP +L E +P L + GG Q S S +I + +
Sbjct 436 APASQQPSVILVEENKPRPLLI-----GGTE--STHQAVHTQLSNPSSLANIDFYAQVSD 488
Query 837 V-SSVN 841
+ + N
Sbjct 489 ITPAGN 494
>sp|P31836|NCAM1_BOVIN Neural cell adhesion molecule 1 OS=Bos
taurus OX=9913 GN=NCAM1 PE=1 SV=1
Length=853
Score = 95.3 bits (235), Expect = 1e-18, Method: Composition-based stats.
Identities = 73/431 (17%), Positives = 130/431 (30%), Gaps = 64/431 (15%)
Query 44 FTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQY--------------TIINRTASSV 89
T C + I W+T+ I E+ ++ R+ + V
Sbjct 324 VTLTC-------EASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARV 376
Query 90 TFTDIASLNIQLTCNILT-----FGQLEQNVYGITIISGLPPE--KPKNLSCIVNEGKKM 142
+ + S+ + GQ Q++Y + P+ P + +
Sbjct 377 SSLTLKSIQYTDAGEYVCTASNTIGQDSQSMY---LEVQYAPKLQGPVAVYTWEGNQVNI 433
Query 143 RCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN 202
C E + T+ Y+T +EV ++EN
Sbjct 434 TC------EVFAYPSATISWFRDGQLLPSSNYSN------IKIYNTPSASYLEVTPDSEN 481
Query 203 ALGKVTSDHINF-----DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILK 256
G +N V+ + P + S+ E SS ++ + P ILK
Sbjct 482 DFGNYNCTAVNRIGQESLEFVLVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILK 541
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSS-FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y ++R W + ++ T+ LKP T Y R+ + G G S SE
Sbjct 542 YKAEWRAMGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASE 601
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT---- 371
+ E PS K++ + ++++ K + + I Y V
Sbjct 602 FKTQPVRE--PSAP-----KLEGQMGEDGNSIKV--KLIKQDDGGSPIRHYLVKYRALSS 652
Query 372 RWKSHLQNYTVNATKLTVNLT-NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
WK ++ + + + +L N Y + N GKS AA P
Sbjct 653 EWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGS 712
Query 431 KAFPKDNMLWV 441
V
Sbjct 713 PTSGLSTGAIV 723
Score = 87.6 bits (215), Expect = 3e-16, Method: Composition-based stats.
Identities = 40/258 (16%), Positives = 83/258 (32%), Gaps = 12/258 (5%)
Query 386 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT 445
++T + ND T N +G+ + + A + + P + V++
Sbjct 474 EVTPDSENDFGNYNCTAVNRIGQESLEFVLVQADTPSSPSID---QVEPYSSTAQVQFDE 530
Query 446 PRE----SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
P + KY EW + ++ + ++ ++ L Y + + +
Sbjct 531 PEATGGVPILKYKAEWRAMGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNG 590
Query 502 DGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G G + + + P + + ++ + D IR+Y + YR
Sbjct 591 KGLGEISAASEFKTQPVREPSAPKLEGQMGEDGN-SIKVKLIKQDDGGSPIRHYLVKYRA 649
Query 561 IIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE 619
+ + + S L SL + Y V + A +G F F T I
Sbjct 650 LSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRT-SAQPTAIP 708
Query 620 AIVVPVCLAFLLTTLLGV 637
A P ++G+
Sbjct 709 ANGSPTS-GLSTGAIVGI 725
>sp|P36335|NCA12_XENLA Neural cell adhesion molecule 1-B OS=Xenopus
laevis OX=8355 GN=ncam1-b PE=2 SV=1
Length=1092
Score = 95.3 bits (235), Expect = 1e-18, Method: Composition-based stats.
Identities = 74/404 (18%), Positives = 125/404 (31%), Gaps = 64/404 (16%)
Query 42 SNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTA-------SSVTFTDI 94
T C + I W+T H I E+ T+ S++T DI
Sbjct 317 DEITLTC-------EASGDPIPSITWRTAHRNISSEEKTLDGHIVVKDHIRMSALTLKDI 369
Query 95 ASLNI-QLTCNILTF-GQLEQNVYGITIISGLPPEK------------PKNLSCIVNEGK 140
+ + C G Q +Y P+ P N++C V
Sbjct 370 QYTDAGEYFCVASNPIGVDMQAMY---FEVQYAPKIRGPVVVYTWEGNPVNITCDVLAHP 426
Query 141 KMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
W + +NF+ + F+ + D+ F N A
Sbjct 427 SAAVSWFRDGQLLPSSNFSNIKIYNGPTFSSLEVNPDSEND---------FGNY--NCSA 475
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNI 259
N++G +S+ I V+ + P + ++ E SS + + + P ILKY
Sbjct 476 VNSIGHESSEFIL------VQADTPSSPAIRKVEPYSSTVMIVFDEPDATGGVPILKYKA 529
Query 260 QYRTKDASTWSQIPPEDTASTRSSF-TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
++R W + + S TV LKP T Y+ ++ + G G S S++ +
Sbjct 530 EWRVVGQEKWHARYYDAKEVSAESIITVTGLKPETSYMVKLSAVNGKGLGD-STPSQDFT 588
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW----K 374
+ PS AP + + + I Y V
Sbjct 589 TQPVKGEPS-APKLVGHLSEDGNSIKVDII------KQDDGGSPIRHYLVNYRALNAVDW 641
Query 375 SHLQNYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAAVLTI 416
N+ +T+ Y + N GKS A L+
Sbjct 642 KPEMRVPSNSHHVTLKTLEWNVDYEVIVVAENQQGKSKQARLSF 685
Score = 91.1 bits (224), Expect = 3e-17, Method: Composition-based stats.
Identities = 41/238 (17%), Positives = 82/238 (34%), Gaps = 14/238 (6%)
Query 381 TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW 440
T ++ ++ + ND + N +G + + + A + K P + +
Sbjct 454 TFSSLEVNPDSENDFGNYNCSAVNSIGHESSEFILVQADTPSSPAI---RKVEPYSSTVM 510
Query 441 VEWTTPRE----SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV 496
+ + P + KY EW V+ + + ++ + L Y++ +
Sbjct 511 IVFDEPDATGGVPILKYKAEWRVVGQEKWHARYYDAKEVSAESIITVTGLKPETSYMVKL 570
Query 497 TPVYADGPGSPESIKAYLKQAP---PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
+ V G G + + Q PS V N + D + D IR+
Sbjct 571 SAVNGKGLGDSTPSQDFTTQPVKGEPSAPKLVGHLSEDGNSIKV--DIIKQDDGGSPIRH 628
Query 554 YTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT 609
Y + YR + + + V S+ TL +L + Y V + A +G +F
Sbjct 629 YLVNYRALNAVDWKPEMRVPSNSHHVTLKTLEWNVDYEVIVVAENQQGKSKQARLSFR 686
>sp|P08941|ROS1_CHICK Proto-oncogene tyrosine-protein kinase ROS
OS=Gallus gallus OX=9031 GN=ROS1 PE=1 SV=3
Length=2311
Score = 95.3 bits (235), Expect = 2e-18, Method: Composition-based stats.
Identities = 45/270 (17%), Positives = 81/270 (30%), Gaps = 19/270 (7%)
Query 360 NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG-KSDAAVLTIPA 418
+ D V T+ L N T R T++ + DA +
Sbjct 47 LCNVSDINVACTQGCQFWNATEQVNCPLKCNKTYTRECETVSCKFGCSRAEDAYGVEAQN 106
Query 419 CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
C + P + + + + W S KYI++W DW+ +
Sbjct 107 CLNKPGAP---FASSIGSHNITLGWKPANISEVKYIIQWKFHQLPG----DWRYTEVVSE 159
Query 479 RTYLRGNLAESKCYLITVTPVYADGPG---SPESIKAYLKQAPPSKGPTVR-TKKVGKNE 534
+Y +L Y V + P P+ P ++ + N
Sbjct 160 TSYTVKDLQAFTEYEFRVVWIITSQLQLHSPPSPSYRTHASGVPTTAPIIKDIQSSSPNT 219
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH-TEYTLSSLTSDTLYMVRMA 593
+ W P NG I Y + ++ +E + +S + S ++ Y +
Sbjct 220 VEVSW--FPPLFPNGLIVGYNL----VLTSENHELLRASRGHSFQFYSTFPNSTYRFSIV 273
Query 594 AYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
A + G E TTP+ E +
Sbjct 274 AVNEAGAGPPAEANITTPESKVKEKAKWLF 303
Score = 90.3 bits (222), Expect = 6e-17, Method: Composition-based stats.
Identities = 44/203 (22%), Positives = 73/203 (36%), Gaps = 19/203 (9%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
KP P S+ + + L W ++ +KY IQ++ + +
Sbjct 110 KPGAPFASSIGSHN-----ITLGWKP---ANISEVKYIIQWKFHQLPGDWRYTE---VVS 158
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
+S+TV+DL+ FTEY FR+ + S S S P+ I
Sbjct 159 ETSYTVKDLQAFTEYEFRVVWIITSQLQLHSPPSPSYRTHA-----SGVPTTAPIIKDIQ 213
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT-KLTVNLTNDRYLAT 399
+ TV++ W PP NG I+ Y + LT L + + + N Y +
Sbjct 214 SSSPNTVEVSW--FPPLFPNGLIVGYNLVLTSENHELLRASRGHSFQFYSTFPNSTYRFS 271
Query 400 LTVRNLVGKSDAAVLTIPACDFQ 422
+ N G A I + +
Sbjct 272 IVAVNEAGAGPPAEANITTPESK 294
Score = 85.7 bits (210), Expect = 2e-15, Method: Composition-based stats.
Identities = 101/624 (16%), Positives = 182/624 (29%), Gaps = 81/624 (13%)
Query 79 YTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPP-EKPKNL----- 132
Y I+N T + + ++ CN + + G I + +KP+ L
Sbjct 1312 YDILNNTMYHILGYESVEEKMRNYCNC----NVAEAELGRPISIDVTDIKKPQLLFIRGR 1367
Query 133 -SCIVNEGKKMRCEWDGGRETHLET-NFTLKSEWATHK--FADCKAKRDTPTSCTVDYST 188
++ C R T + + T K K++ C D +
Sbjct 1368 DEIWASDVDACHCW----RITKIPSFQGTKIGSLTVDKQFIYWTIEKKEYTEICLADKES 1423
Query 189 VYFV-----NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
N E+ + A ++ + D P+ P L N+ S+ +T
Sbjct 1424 TRHSLQRKANHELKILAYSSAMQSYPDKKCLTPLLDT--EKPTILDTTNTSFTLSLPSVT 1481
Query 244 WTN--PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS------FTVQDLKPFTEY 295
PSI Y + +R ++ + T ++ + +LKPF+ Y
Sbjct 1482 TQQLCPSISQ-PTPTYLVFFREITSNHENSTYHFSTLLQKTLEIQEPIAVINNLKPFSTY 1540
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW-KTL 354
++ EA T P S + T+ + W + L
Sbjct 1541 AIQVAVKNYYSNQNQLAVGREAISTTLYGVPEGVDSIKTVV-----LSDTTINISWSEPL 1595
Query 355 PPFEANGKILDYEVTLT-----RWKSHLQNYTVNAT---KLTVNLTNDRYLATLTV-RNL 405
P I Y++++ ++ N T ++ + L +
Sbjct 1596 EPNGPLESIR-YQISVNLLSLFPEAPLRKSEFPNGTLSWSVSDLQSGTNNLFKVLAFHPN 1654
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAP 465
+V I P P++ +EW P W LS K
Sbjct 1655 ENWFSESVPVIAKTFETPLSPSN---IIPRNTSFQLEWRAPLH--INGTSFWFELS-KWQ 1708
Query 466 CITDWQQEDGTV-----HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPP 519
+DW T T S YL+ T VY G S S ++ P
Sbjct 1709 TRSDWFSPASTTCTVGPVYTCNLTGTLPSANYLVRATVVYVTGMKSTSSPTSFKTTAGVP 1768
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD-------- 571
SK T + + KN ++W+ + + Y + R GN V
Sbjct 1769 SKPGTPKRAEDSKNS--VQWE--KAEDNGSNLTYYILESRKQSGNTNKVKSLWVVVYNGS 1824
Query 572 -SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD----GPEFTFTTPKFAQGEIEAIVVPVC 626
+ + +L + R AA G + + +I AIV +
Sbjct 1825 CDNICTWKAENLEG--TFQFRAAAANMLGLGEYSDTSKDIVLAKDTVTSPDITAIVAVIG 1882
Query 627 LAFLLTTLLGVLFCFNKRDLIKKH 650
L T++ + + +
Sbjct 1883 AVVLGLTIIILFGFVWHQRWKSRK 1906
Score = 77.2 bits (188), Expect = 6e-13, Method: Composition-based stats.
Identities = 33/239 (14%), Positives = 70/239 (29%), Gaps = 23/239 (10%)
Query 384 ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEW 443
+++ + A T+ + K + ++ P K + + W
Sbjct 911 NQSISIPFSEPAEFAAFTLVHTSLKPLPGNFSFTPKVIPSSVPESSFKIKGNSSSFHIIW 970
Query 444 TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR----TYLRGNLAESKCYLITVTPV 499
V+ + +CV S+ T + H +Y L + +VTP
Sbjct 971 NAST-DVQWGTVFYCVGSNALQMRTLESERCLHPHDLTVPSYKVDWLEPFTLFDFSVTPY 1029
Query 500 YADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE--------AVLEWDQLPVDVQNGFI 551
G S+ + PS R + N L WD + NG +
Sbjct 1030 TYWGKAPTTSVYLRAPEGVPSAPANPRIYVLHSNTHEGEEKVLVELRWD--KPERDNGVL 1087
Query 552 RNYTIFYRTIIG--------NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ ++Y+ + +V + +++ ++ A+T G
Sbjct 1088 TQFRVYYQLLYESGAADTLMEWNVSDVKPTALLFSIRDEHPRLTVRFQVQAFTSVGPGP 1146
Score = 65.3 bits (157), Expect = 3e-09, Method: Composition-based stats.
Identities = 33/206 (16%), Positives = 68/206 (33%), Gaps = 15/206 (7%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN-FTLKSEWATHKFADCKAKRDTPTSC 182
+P P++ I W+ + T + + S + + +
Sbjct 948 IPSSVPESSFKIKGNSSSFHIIWNASTDVQWGTVFYCVGSNALQMRTLESERCLHPHDLT 1007
Query 183 TVDYSTVY---FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSV------INS 233
Y + F + V GK + + V P+ P N + +
Sbjct 1008 VPSYKVDWLEPFTLFDFSVTPYTYWGKAPTTSVYLRAPEGV-PSAPANPRIYVLHSNTHE 1066
Query 234 EELSSILKLTWTNPSIKSVIILK----YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
E +++L W P + ++ + Y + Y + A T + D T F+++D
Sbjct 1067 GEEKVLVELRWDKPERDNGVLTQFRVYYQLLYESGAADTLMEWNVSDVKPTALLFSIRDE 1126
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSE 315
P F+++ G G SD ++
Sbjct 1127 HPRLTVRFQVQAFTSVGPGPMSDVAQ 1152
Score = 56.4 bits (134), Expect = 1e-06, Method: Composition-based stats.
Identities = 39/206 (19%), Positives = 63/206 (31%), Gaps = 45/206 (22%)
Query 221 KPNP-PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW---------S 270
+P P P ++ S ++W+ P Y I W S
Sbjct 567 QPYPLPTLPRLVTVLFGSDQAVISWSPPE--------YTIGTSRSAWQNWTYDVKVSSQS 618
Query 271 QIPPEDTAS--TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP-- 326
E S T + F V++L FTEY +R + G+G WS+ + E+ P
Sbjct 619 TFEEEWVVSNITDTRFAVKNLVSFTEYEMSVRAVSPAGEGPWSEPFRGMTFEEAEEEPYI 678
Query 327 --SKAPSFWYKIDPSHTQGY------RTV--------QLVWKTLPPFEANGKILDYEVTL 370
A W + S+ G R + L W + GK+ + +
Sbjct 679 LAVGAEGLWKQRLDSYGPGEFLYPHIRNISDLDWYNDTLYW-----SNSMGKVQTWSMNK 733
Query 371 TRWKSHLQNYTV--NATKLTVNLTND 394
+ NA L +
Sbjct 734 KEGTTENSYVPDIKNARMLAFDWLGQ 759
Score = 54.9 bits (130), Expect = 4e-06, Method: Composition-based stats.
Identities = 24/188 (13%), Positives = 51/188 (27%), Gaps = 19/188 (10%)
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ---NYTVNATKLTVNLTN-- 393
+ + G + L WK E + Y + + V+ T TV
Sbjct 116 ASSIGSHNITLGWKPANISE-----VKYIIQWKFHQLPGDWRYTEVVSETSYTVKDLQAF 170
Query 394 DRYLATLT-VRNL---VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES 449
Y + + + + A T P++ N + V W P
Sbjct 171 TEYEFRVVWIITSQLQLHSPPSPSYRTHASGVPTTAPIIKDIQSSSPNTVEVSWFPPL-F 229
Query 450 VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES 509
I+ + ++ + ++ + + Y ++ V G G P
Sbjct 230 PNGLIVGYNLVLTSENHEL----LRASRGHSFQFYSTFPNSTYRFSIVAVNEAGAGPPAE 285
Query 510 IKAYLKQA 517
++
Sbjct 286 ANITTPES 293
Score = 47.2 bits (110), Expect = 0.001, Method: Composition-based stats.
Identities = 14/113 (12%), Positives = 31/113 (27%), Gaps = 8/113 (7%)
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITD------W 470
+ + + + W+ P ++ W + + W
Sbjct 565 STQPYPLPTLPRLVTVLFGSDQAVISWSPPEYTIGTSRSAWQNWTYDVKVSSQSTFEEEW 624
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSKG 522
+ T R ++ NL Y ++V V G G E + + +
Sbjct 625 VVSNITDTRFAVK-NLVSFTEYEMSVRAVSPAGEGPWSEPFRGMTFEEAEEEP 676
Score = 42.2 bits (97), Expect = 0.027, Method: Composition-based stats.
Identities = 22/101 (22%), Positives = 40/101 (40%), Gaps = 11/101 (11%)
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN------YTIFYRTIIG-NET 566
+ P P + T G ++AV+ W P + G R+ Y + + E
Sbjct 566 TQPYPLPTLPRLVTVLFGSDQAVISWS--PPEYTIGTSRSAWQNWTYDVKVSSQSTFEEE 623
Query 567 AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
V + + T + + +L S T Y + + A + G +GP
Sbjct 624 WVVSNITDTRFAVKNLVSFTEYEMSVRAVSPAG--EGPWSE 662
>sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mus
musculus OX=10090 GN=Tie1 PE=1 SV=3
Length=1134
Score = 94.5 bits (233), Expect = 3e-18, Method: Composition-based stats.
Identities = 64/432 (15%), Positives = 117/432 (27%), Gaps = 52/432 (12%)
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
C G S + + P AP K R + + L F +
Sbjct 424 CRVSTSGGQDSRRFKVNVKVPP--VPLTAPRLLAK-------QSRQLVVS--PLVSFSGD 472
Query 361 GKILDYEVTLTRWKSH--LQNYTVNATKLTVNL---TNDRYLATLT----VRNLVGKSDA 411
G I + S V+ ++ + Y + G
Sbjct 473 GPISSVRLHYRPQDSTIAWSAIVVDPSENVTLMNLKPKTGYNVRVQLSRPGEGGEGGWGP 532
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP--RESVKKYILEWCVLSDKAPCITD 469
+ L C P ++ + L V W+ P S ++L +
Sbjct 533 SALMTTDCPEPLLQPWLESWHVEGPDRLRVSWSLPSVPLSGDGFLLRLWDGARGQERR-- 590
Query 470 WQQEDGTVHRTYLRGNLAESKCYLI--TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
+ RT L L Y + + GP SP +L + P +
Sbjct 591 -ENISFPQARTALLTGLTPGTHYQLDVRLYHCTLLGPASP-PAHVHLPPSGPPAPRHLHA 648
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD---SSHTEYTLSSLTS 584
+ + +E L W + +G I Y + + G+ +D T + L +
Sbjct 649 QALSDSEIQLMWQH--PEAPSGPISKYIVEIQVAGGSGDPQWMDVDRPEETSIIVRGLNA 706
Query 585 DTLYMVRMAAYTDEGGK----------------DGPEFTFTTPKFAQGEIEAIVVPVCLA 628
T Y+ R+ A G +GP + + + V ++
Sbjct 707 STRYLFRVRASVQGLGDWSNTVEEATLGNGLQSEGPVRESRAAEEGLDQQLVLAVVGSVS 766
Query 629 FLLTTL---LGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSD 685
T+ L L C + L ++ + + I Q+S T
Sbjct 767 ATCLTILAALLALVCIRRSCLHRRRTFTYQSGSGEETILQFSSGTLTLTRRPKPQPEPLS 826
Query 686 GNFTDVSVVEIE 697
+ + E
Sbjct 827 YPVLEWEDITFE 838
Score = 93.4 bits (230), Expect = 6e-18, Method: Composition-based stats.
Identities = 64/327 (20%), Positives = 107/327 (33%), Gaps = 30/327 (9%)
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS-T 268
D F KV P P ++ S L ++ I + YR +D++
Sbjct 433 DSRRFKVNVKVPPVPLTAPRLLAK--QSRQLVVSPLVSFSGDGPISSVRLHYRPQDSTIA 490
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR-CMKEDGKGYWSDWSEEASGITYEDRPS 327
WS I + T+ +LKP T Y R++ +G S + D P
Sbjct 491 WSAI----VVDPSENVTLMNLKPKTGYNVRVQLSRPGEGGEGGWGPS----ALMTTDCPE 542
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT---RWKSHLQNYTVNA 384
W ++ H +G +++ W +LP +G + + L R + +N +
Sbjct 543 PLLQPW--LESWHVEGPDRLRVSW-SLPSVPLSGD--GFLLRLWDGARGQERRENISFPQ 597
Query 385 TK---LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLW 440
+ LT Y + + + A+ L A D+ +
Sbjct 598 ARTALLTGLTPGTHYQLDVRLYHCTLLGPASPPAHVHLPPSGPPAPRHLHAQALSDSEIQ 657
Query 441 VEWTT---PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
+ W P + KYI+E + W D + + L S YL V
Sbjct 658 LMWQHPEAPSGPISKYIVE--IQVAGGSGDPQWMDVDRPEETSIIVRGLNASTRYLFRVR 715
Query 498 P-VYADGPGSPESIKAYLKQAPPSKGP 523
V G S +A L S+GP
Sbjct 716 ASVQGLGDWSNTVEEATLGNGLQSEGP 742
Score = 71.4 bits (173), Expect = 3e-11, Method: Composition-based stats.
Identities = 38/183 (21%), Positives = 64/183 (35%), Gaps = 16/183 (9%)
Query 142 MRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTP---TSCTVDYSTVYFVNIEVWV 198
+R W L + L W + + + P T+ + ++V +
Sbjct 560 LRVSWSLPSVP-LSGDGFLLRLWDGARGQERRENISFPQARTALLTGLTPGTHYQLDVRL 618
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
LG + V+ PP + S ++L W +P S I KY
Sbjct 619 YHCTLLGPASPPAH----VHLPPSGPPAPRHLHAQALSDSEIQLMWQHPEAPSGPISKYI 674
Query 259 IQYRTKDAST---WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
++ + S W + +S V+ L T Y+FR+R G G WS+ E
Sbjct 675 VEIQVAGGSGDPQWMDVDR----PEETSIIVRGLNASTRYLFRVRAS-VQGLGDWSNTVE 729
Query 316 EAS 318
EA+
Sbjct 730 EAT 732
>sp|P54760|EPHB4_HUMAN Ephrin type-B receptor 4 OS=Homo sapiens
OX=9606 GN=EPHB4 PE=1 SV=2
Length=987
Score = 94.2 bits (232), Expect = 3e-18, Method: Composition-based stats.
Identities = 41/201 (20%), Positives = 70/201 (35%), Gaps = 16/201 (8%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWA--THKFADCKAK----- 175
PP P+++ +N G + EW E+ + + L+ A C
Sbjct 323 PPSAPRSVVSRLN-GSSLHLEWSAPLESGGREDLTYALRCRECRPGGSCAPCGGDLTFDP 381
Query 176 --RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN--PPHNLSVI 231
RD V V A N + + + + F+PV PP +
Sbjct 382 GPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTDREVPPAVSDIR 441
Query 232 NSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ S L L W P S +L Y ++Y K A S + ++ + ++ LK
Sbjct 442 VTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVR--FLKTSENRAELRGLKR 499
Query 292 FTEYVFRIRCMKEDGKGYWSD 312
Y+ ++R E G G +
Sbjct 500 GASYLVQVRARSEAGYGPFGQ 520
Score = 91.8 bits (226), Expect = 2e-17, Method: Composition-based stats.
Identities = 35/197 (18%), Positives = 64/197 (32%), Gaps = 19/197 (10%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDK-------APCITDWQQEDG 475
+ + + L +EW+ P ES + L + + + APC D + G
Sbjct 323 PPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPGGSCAPCGGDLTFDPG 382
Query 476 ---TVHRTYLRGNLAESKCYLITVTPVYA-----DGPGSPESIKAYLKQAPPSKGPTVRT 527
V + L Y VT + GP E + + P +R
Sbjct 383 PRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTDREVPPAVSDIRV 442
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSHTEYTLSSLTSD 585
+ + L W +G + +Y + Y G + + +S L L
Sbjct 443 TRSSPSSLSLAWAV--PRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAELRGLKRG 500
Query 586 TLYMVRMAAYTDEGGKD 602
Y+V++ A ++ G
Sbjct 501 ASYLVQVRARSEAGYGP 517
Score = 59.5 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 36/210 (17%), Positives = 59/210 (28%), Gaps = 28/210 (13%)
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN 379
P P + S G ++ L W + P + L Y + +
Sbjct 313 TDPRGAPCTTPPSAPRSVVSRLNGS-SLHLEW-SAPLESGGREDLTYALRCRECRPGGSC 370
Query 380 YTVNA-------------TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP------ACD 420
+ V + T V L G S A +P D
Sbjct 371 APCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTD 430
Query 421 FQATHPVMDLKAFPKD-NMLWVEW---TTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
+ V D++ + L + W P +V Y +++ + P + +
Sbjct 431 REVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSEN 490
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGS 506
R LRG L YL+ V G G
Sbjct 491 --RAELRG-LKRGASYLVQVRARSEAGYGP 517
>sp|Q60629|EPHA5_MOUSE Ephrin type-A receptor 5 OS=Mus musculus
OX=10090 GN=Epha5 PE=1 SV=2
Length=876
Score = 93.8 bits (231), Expect = 3e-18, Method: Composition-based stats.
Identities = 35/125 (28%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY 577
PS V+ K+ KN L W + D NG I Y I Y + + S T
Sbjct 306 APSPVTNVKKGKIAKNSISLSWQE--PDRPNGIILEYEIKYFEKDQETSYTIIKSKETSI 363
Query 578 TLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTF-TTP-----KFAQGEIEAIVVPVCLAFL 630
T L ++Y+ ++ A T G G F F TTP Q +I I V V + +
Sbjct 364 TAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVSVAASNDQSQIPIIAVSVTVGVI 423
Query 631 LTTLL 635
L ++
Sbjct 424 LLAVM 428
Score = 81.1 bits (198), Expect = 3e-14, Method: Composition-based stats.
Identities = 29/103 (28%), Positives = 44/103 (43%), Gaps = 5/103 (5%)
Query 224 PPHNLS-VINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P ++ V + + + L+W P + IIL+Y I+Y KD T S +
Sbjct 306 APSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQET----SYTIIKSKET 361
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
S T + LKP + YVF+IR G G +S E +
Sbjct 362 SITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVSVAA 404
Score = 52.6 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 17/85 (20%), Positives = 29/85 (34%), Gaps = 3/85 (4%)
Query 422 QATHPVMDLK-AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
QA PV ++K N + + W P + ILE+ + + T +
Sbjct 305 QAPSPVTNVKKGKIAKNSISLSWQEP-DRPNGIILEYEIKYFEKDQETSYTIIKSKETS- 362
Query 481 YLRGNLAESKCYLITVTPVYADGPG 505
L + Y+ + A G G
Sbjct 363 ITAEGLKPASVYVFQIRARTAAGYG 387
Score = 39.5 bits (90), Expect = 0.20, Method: Composition-based stats.
Identities = 19/111 (17%), Positives = 33/111 (30%), Gaps = 7/111 (6%)
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA--T 385
+APS + ++ L W+ P NG IL+YE+ + + T
Sbjct 305 QAPSPVTNVK-KGKIAKNSISLSWQE--PDRPNGIILEYEIKYFEKDQETSYTIIKSKET 361
Query 386 KLTVNLTNDR--YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP 434
+T Y+ + R G + + D P
Sbjct 362 SITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVSVAASNDQSQIP 412
>sp|Q967D7|TUTL_DROME Protein turtle OS=Drosophila melanogaster
OX=7227 GN=tutl PE=1 SV=2
Length=1531
Score = 94.2 bits (232), Expect = 3e-18, Method: Composition-based stats.
Identities = 100/696 (14%), Positives = 192/696 (28%), Gaps = 139/696 (20%)
Query 31 ISPESPV-VQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSV 89
++PE + V L + C I+W + + I + +
Sbjct 257 VTPEDIIYVNLGDSIILNC-------QADGTPTPEILWYKDANPVDPSPTVGIFNDGTEL 309
Query 90 TFTDIASLNI-QLTCNILTFGQLEQNVYGITIISG----LPP-------EKPKNLSCIVN 137
+ I +I + TC + + I G +PP + SC
Sbjct 310 RISTIRHEDIGEYTCIARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVIFSCEAK 369
Query 138 E-GKKMRCEW----DGGRE-THLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF 191
+ W RE LET T++ + + K C
Sbjct 370 AMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLI-INPIKPDDSGQYLC--------- 419
Query 192 VNIEVWVEAENALGKVTSD--------HINFDPVYKVKPNPPHNLSVI--NSEELSSILK 241
E N +G S V+ P V+ + +
Sbjct 420 -------EVTNGIGDPQSASAYLSVEYPAKVTFTPTVQYLPFRLAGVVQCYIKSSPQLQY 472
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+TWT +I + ++++ E Q T Y
Sbjct 473 VTWTKDKRLLEPYQMKDIVVMANGSLLFTRVNEEH----------QGQYACTPY------ 516
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT----------QGYRTVQLVW 351
G S + + P Y+ + +G + W
Sbjct 517 -NAQGTAGASGVMDVLVRKPP--AFTVEPETLYQRKVGDSVEMHCDALEAEGTERPTIKW 573
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV-NLTNDRYLATLTVRNLVGKSD 410
+ G+ +S ++ +T+ NL + + V + +
Sbjct 574 Q-----RQEGE--------QLTESQRNRIKISGGNITIENLRREDFGYYQCVVSNEVATL 620
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW 470
AV + + H ++ ++ + ++W +Y ++ + +A + DW
Sbjct 621 MAVTQL-VIEGTQPHAPYNITGKATESSITLQWLPGYSGGSEYKQDYTIWFREA-GVNDW 678
Query 471 QQEDGTVHRT--YLRGNLAESKCYLITVTPVYADGPGSPESIK-AYLKQAPPSKGPTVRT 527
Q T + LA Y V G G + + P+ V+
Sbjct 679 QTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLGDGMMSKVMTVRTLEDAPAAPRNVKA 738
Query 528 KKVGKNEA---------------------------VLEWDQLPVDVQNGFIRNYTIFYRT 560
+ ++ W + ++ YTI YRT
Sbjct 739 ATQPPDSFFQLMPDEAGPKPGPPRNVSVTEVSNGFLITWQS--PLERAHIVKFYTIKYRT 796
Query 561 IIGNET--AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEI 618
+T + T+Y + +L Y R+ A +++ + E F P A+ +
Sbjct 797 DAQWKTLNRGQIRPEETQYLVKNLVGGRTYYFRVLANSEKSYESSDEVKF--PVPARVKH 854
Query 619 EAIVVPVCLAFLLTTLLGVL-FC----FNKRDLIKK 649
+AI V L + +L C NKR K+
Sbjct 855 KAITAGVVGGILFFIVAIILSVCAVKICNKRKRRKQ 890
>sp|P16882|GHR_MOUSE Growth hormone receptor OS=Mus musculus OX=10090
GN=Ghr PE=1 SV=1
Length=650
Score = 93.4 bits (230), Expect = 3e-18, Method: Composition-based stats.
Identities = 47/219 (21%), Positives = 84/219 (38%), Gaps = 34/219 (16%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA---------------THKFAD 171
KP+ C E + C W G L+T +++ +A T ++ +
Sbjct 49 GKPRFTKCRSPELETFSCYWTEGDNPDLKTPGSIQLYYAKRESQRQAARIAHEWTQEWKE 108
Query 172 CKAK-RDTPTSCTVDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS 229
C SC + S T ++ + + L D F V+P+PP L+
Sbjct 109 CPDYVSAGKNSCYFNSSYTSIWIPYCIKLTTNGDL----LDQKCFTVDEIVQPDPPIGLN 164
Query 230 ----VINSEELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTR 281
I+ + ++++W P V IIL+Y IQY+ + S W + P
Sbjct 165 WTLLNISLTGIRGDIQVSWQPPPNADVLKGWIILEYEIQYKEVNESKWKVMGPIWL---- 220
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
+ V L+ E+ R+R + + +S++SE I
Sbjct 221 TYCPVYSLRMDKEHEVRVRSRQRSFE-KYSEFSEVLRVI 258
Score = 50.6 bits (119), Expect = 6e-05, Method: Composition-based stats.
Identities = 75/477 (16%), Positives = 135/477 (28%), Gaps = 79/477 (17%)
Query 377 LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
+ + T + ++ T + +G S + C
Sbjct 14 VTSSTFSGSEATPATLGKASPVLQRINPSLGTSSSGKPRFTKCRSPEL---------ETF 64
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKA--------PCITDWQQ----EDGTVHRTYLRG 484
+ W E P I + + +W++ + Y
Sbjct 65 SCYWTEGDNPDLKTPGSIQLYYAKRESQRQAARIAHEWTQEWKECPDYVSAGKNSCYFNS 124
Query 485 NLAESK-CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN----EAVLEW 539
+ Y I +T ++ ++ PP + + + W
Sbjct 125 SYTSIWIPYCIKLTTNGDLLDQKCFTVDEIVQPDPPIGL-NWTLLNISLTGIRGDIQVSW 183
Query 540 DQLP-VDVQNG-FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
P DV G I Y I Y+ + ++ V T + SL D + VR+ +
Sbjct 184 QPPPNADVLKGWIILEYEIQYKEVNESKWKVMGPIWLTYCPVYSLRMDKEHEVRVRSRQR 243
Query 598 EGGKDGPEFTFTTPKFAQGEI-----EAIVVPVCLAFLL----TTLLGVLFCFNKRDLIK 648
K F Q I E I P L + ++ + F+K+ IK
Sbjct 244 SFEKYSEFSEVLRVIFPQTNILEACEEDIQFPWFLIIIFGIFGVAVMLFVVIFSKQQRIK 303
Query 649 KHIWPNVPDPSKSHIAQWSPHTPPRHNF-----------NSKDQMYSDGNFTDVSVVEIE 697
I P VP P I P N K Y+D ++ + ++I+
Sbjct 304 MLILPPVPVP---KIKGIDPDLLKEGKLEEVNTILGIHDNYKPDFYNDDSWVEFIELDID 360
Query 698 ANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGG----SSCMSSSRPSISSSD-------- 745
D E + D + + E + +G S S P I +D
Sbjct 361 EAD---VDEKTEGSDTDRLLSNDHEKSAGILGAKDDDSGRTSCYDPDILDTDFHTSDMCD 417
Query 746 ------ENESSQNTSSTVQYST--VVHSGYRHQV----PSVQVFSRSESTQPLLDSE 790
+++ + + + + Y + PS+ QPLL SE
Sbjct 418 GTLKFRQSQKLNMEADLLCLDQKNLKNLPYDASLGSLHPSITQTVEENKPQPLLSSE 474
>sp|Q95ML5|GHR_SAIBB Growth hormone receptor OS=Saimiri boliviensis
boliviensis OX=39432 GN=GHR PE=2 SV=1
Length=632
Score = 93.0 bits (229), Expect = 4e-18, Method: Composition-based stats.
Identities = 38/206 (18%), Positives = 76/206 (37%), Gaps = 31/206 (15%)
Query 128 KPKNLSCIVNEGKKMRCEW---------DGGRETHLETNFTLKSEWATHKFADCKAK-RD 177
+PK C E + C W G T ++ T ++ +C
Sbjct 50 EPKFTKCRSPELETFSCRWTDAVHHGLKSPGPIQLFYTR--RNTQEGTQEWKECPDYVSA 107
Query 178 TPTSCTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS----VIN 232
SC + S ++ + + + T D F V+P+PP L+ I+
Sbjct 108 GENSCYFNSSFTSIWIPYCIKLTSNGG----TVDEKCFSVDQIVQPDPPIALNWTLLNIS 163
Query 233 SEELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
+ + +++ W P + ++L+Y +QY+ + + W + P +S +
Sbjct 164 LTGVHADIQVRWEAPPNADIQKGWMVLEYELQYKEVNETQWKMMDPIL----STSVPLYS 219
Query 289 LKPFTEYVFRIRCMKEDG--KGYWSD 312
L+ EY R+R + G +S+
Sbjct 220 LRVDKEYEVRVRSRQRKSENYGEFSE 245
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 86/464 (19%), Positives = 148/464 (32%), Gaps = 77/464 (17%)
Query 490 KCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN----EAVLEWDQLP-V 544
Y I +T S+ ++ PP + + + W+ P
Sbjct 123 IPYCIKLTSNGGTVDEKCFSVDQIVQPDPPIAL-NWTLLNISLTGVHADIQVRWEAPPNA 181
Query 545 DVQNG-FIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY---TDEGG 600
D+Q G + Y + Y+ + + + T L SL D Y VR+ + ++ G
Sbjct 182 DIQKGWMVLEYELQYKEVNETQWKMMDPILSTSVPLYSLRVDKEYEVRVRSRQRKSENYG 241
Query 601 KDGPEFTFTTPKFAQGEIEA-----IVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNV 655
+ P+ +Q E ++ + T++ +F F+K+ IK I P V
Sbjct 242 EFSEVLYVKLPQMSQFTCEEDFYYPWLLIIIFGISGLTVMLFVFLFSKQQRIKMLILPPV 301
Query 656 PDPSKSHIAQWSPHTPPRHNFNS-----------KDQMYSDGNFTDVSVVEIEANDKKPF 704
P P I P K + +SD ++ + ++IE D+K
Sbjct 302 PVP---KIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIEDPDEKTE 358
Query 705 PEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSS--DENESSQNTSSTVQYSTV 762
D L EK + G S S P + + + N+ TS VQ +
Sbjct 359 GLDTDRLLSSDHEKSRSNLGVKD-GDSGRTSCYEPDMLETDFNANDIHDGTSEVVQPQRL 417
Query 763 VH--------------SGYRHQVPSVQV--FSRSESTQP---LLDSEE-----------R 792
S Y P++ ++E +P L+D E
Sbjct 418 KGEADLLCLDQKNQNNSPYHDACPAIHQPSVIQAEKNKPQPLLIDGAESTHQAAHIQLSN 477
Query 793 PEDL-------QLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVN---E 842
P L Q+ D G +L Q SQ + P++ ++ + E
Sbjct 478 PSSLANIDFYAQVSDITPAGSVVLSPGQKNNGGMSQWDMHPEVVSLCQANFIMDNAYFCE 537
Query 843 EDF-----VRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGT 881
D V ++ H S + + E A PGT
Sbjct 538 ADAKKCIPVTPHIKVESHTEPSFNQEDIYITTESLTTTARRPGT 581
>sp|Q4VBE4|EGFLA_MOUSE Pikachurin OS=Mus musculus OX=10090 GN=Egflam
PE=1 SV=1
Length=1017
Score = 93.8 bits (231), Expect = 4e-18, Method: Composition-based stats.
Identities = 37/221 (17%), Positives = 66/221 (30%), Gaps = 15/221 (7%)
Query 411 AAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRES---VKKYILEWCVLSDKAPC 466
A L P +D+K + ++W TP+ S + Y + + +
Sbjct 22 AVSLRTALRKSGKVGPPLDIKLGALNCTAFSIQWKTPKRSGSSIIGYTVFYSEVGSDKSL 81
Query 467 ITDWQQEDGTVHRTYLR---GNLAESKCYLITVTPVYADGPGS---PESIKAYLKQA--P 518
G+L Y ++V G G P + + + P
Sbjct 82 RERSHNVPVGQDTLITEEVIGDLKPGTEYQVSVAAYSQTGKGRLSFPRHVTTLSQDSCLP 141
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTI-IGNETAVNVDSSHTE 576
P+ V +E L W + + I++Y++ F R + T +
Sbjct 142 PAAPQQPHVLVVSDSEVALSWRPG-ENEGSAPIQSYSVEFIRPDFDKSWTIIQERLQMDS 200
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
+ L DT Y + A G + T GE
Sbjct 201 MVIKGLDPDTNYQFAVKAMNAHGFSPRSWPSNTVRTLGPGE 241
Score = 81.8 bits (200), Expect = 2e-14, Method: Composition-based stats.
Identities = 37/216 (17%), Positives = 63/216 (29%), Gaps = 17/216 (8%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT----KDASTWSQIPPED 276
K PP ++ + + + W P I+ Y + Y K S P
Sbjct 34 KVGPPLDIKLGALNC--TAFSIQWKTPKRSGSSIIGYTVFYSEVGSDKSLRERSHNVPVG 91
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ + + DLKP TEY + + GKG S +T + S P +
Sbjct 92 QDTLITEEVIGDLKPGTEYQVSVAAYSQTGKGRLSFP----RHVTTLSQDSCLPPAAPQQ 147
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL------TRWKSHLQNYTVNATKLTVN 390
V L W+ E + I Y V W + +++ +
Sbjct 148 PHVLVVSDSEVALSWRPG-ENEGSAPIQSYSVEFIRPDFDKSWTIIQERLQMDSMVIKGL 206
Query 391 LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
+ Y + N G S + +
Sbjct 207 DPDTNYQFAVKAMNAHGFSPRSWPSNTVRTLGPGEA 242
>sp|Q28575|GHR_SHEEP Growth hormone receptor OS=Ovis aries OX=9940
GN=GHR PE=2 SV=1
Length=634
Score = 93.0 bits (229), Expect = 4e-18, Method: Composition-based stats.
Identities = 37/195 (19%), Positives = 73/195 (37%), Gaps = 23/195 (12%)
Query 133 SCIVNEGKKMRCEWDGGRETHLETNFTLKSEW---ATHKFADCKAK-RDTPTSCTVDYS- 187
C E + C W G L++ +++ + ++ +C SC + S
Sbjct 55 KCRSPELETFSCHWTDGANHSLQSPGSVQMFYIRRDIQEWKECPDYVSAGENSCYFNSSY 114
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK----LT 243
T + + + + + DH F V+P+PP L+ + + +
Sbjct 115 TSVWTPYCIKLTSNGGI----VDHKCFSVEDIVQPDPPVGLNWTLLNISLTEIHADILVK 170
Query 244 WTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
W P V IIL+Y + Y+ + + W + P +S + L+ EY R+
Sbjct 171 WEPPPNTDVKMGWIILEYELHYKELNETQWKMMDPLLV----TSVPMYSLRLDKEYEVRV 226
Query 300 RCMKED--GKGYWSD 312
R + + G +S+
Sbjct 227 RTRQRNTEKYGKFSE 241
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 90/430 (21%), Positives = 139/430 (32%), Gaps = 68/430 (16%)
Query 454 ILEW--CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
I EW C A + + T T Y I +T S++
Sbjct 91 IQEWKECPDYVSAGENSCYFNSSYTSVWT----------PYCIKLTSNGGIVDHKCFSVE 140
Query 512 AYLKQAPPSKGPTVRTKKVGKNEA----VLEWDQLP-VDVQNG-FIRNYTIFYRTIIGNE 565
++ PP G + E +++W+ P DV+ G I Y + Y+ + +
Sbjct 141 DIVQPDPP-VGLNWTLLNISLTEIHADILVKWEPPPNTDVKMGWIILEYELHYKELNETQ 199
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAY---TDEGGKDGPEFTFTTPKFAQGEIEA-I 621
+ T + SL D Y VR+ T++ GK T P+ E
Sbjct 200 WKMMDPLLVTSVPMYSLRLDKEYEVRVRTRQRNTEKYGKFSEVLLITFPQMNPSACEEDF 259
Query 622 VVPVCL----AFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF- 676
P L L T+ L F+K+ IK I P VP P I P
Sbjct 260 QFPWFLIIIFGILGLTVTLFLLIFSKQQRIKMLILPPVPVP---KIKGIDPDLLKEGKLE 316
Query 677 ----------NSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSS 726
N K + Y+D ++ + ++I+ D+K D L EK S
Sbjct 317 EVNTILAIHDNYKHEFYNDDSWVEFIELDIDDPDEKTEGSDTDRLLSNDHEK-----SLS 371
Query 727 GIGG----SSCMSSSRPSISSSDENESS--QNTSSTVQYSTVVHSG------YRHQVPSV 774
G S S P I +D + S TS Q + ++Q S
Sbjct 372 IFGAKDDDSGRTSCYEPDILETDFHVSDMCDGTSEVAQPQRLKGEADILCLDQKNQNNSP 431
Query 775 QVFSRSESTQP--LLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFE 832
+ S QP +L E +P L + GG Q S S +I +
Sbjct 432 SNDAAPASQQPSVILVEENKPRPLPI-----GGTE--STHQAVHTQLSNPSSLANIDFYA 484
Query 833 RSKQV-SSVN 841
+ + + N
Sbjct 485 QVSDITPAGN 494
>sp|Q9YI66|TYRO3_DANRE Tyrosine-protein kinase receptor TYRO3
OS=Danio rerio OX=7955 GN=tyro3 PE=2 SV=1
Length=874
Score = 93.4 bits (230), Expect = 4e-18, Method: Composition-based stats.
Identities = 72/453 (16%), Positives = 135/453 (30%), Gaps = 66/453 (15%)
Query 11 ALFIFLTTESTGELLDPCGYISPESP-VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKT 69
+L I L E + + V + C + ++ I+W
Sbjct 4 SLCILLFLLHFNEGIHGVRFTQKPFHQTVTQGNMVRLGCAFE-------GLSEPEIIWMK 56
Query 70 NHFTI-PKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIIS------ 122
+ + +Q I TF + S+ Q E +G I S
Sbjct 57 DGEKLFSTDQMYITLDPYHWETFHSVKSVQQQDAGKYWC----EVEYHGAIISSEPAWIT 112
Query 123 --GLPP--EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDT 178
G+P +P++++ E + C G E ++ W + + D
Sbjct 113 VAGVPHFGVEPEDVAAFAGESFNLTCAASGPPEP-------VEVLW----WLGGEQNGDF 161
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
S +V + +I+ E NA G S + P +L
Sbjct 162 TPSPSVLFVKGVNESIKFHCEPRNARGISVSRTGTVHIKAR-----PDSLGRTGHHVSDF 216
Query 239 ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ LTW+ + IQ ++P + L+ ++ Y R
Sbjct 217 NITLTWSPGFTGHSQLSTCTIQL--SRGPGEVKLPDVVVEVPPFQHVFEGLRSYSNYSVR 274
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
+RC E G +S W T + PS AP + + + + L W TL E
Sbjct 275 VRCDNEVGSSPFSPW---VDFHTPQAAPSAAPK-----NFTFDLSEQQLTLSWATLEQEE 326
Query 359 ANG----KILDYEVTLT-RWKSHLQN-----YTVNATKLTVNLTNDRYLATLTVRNLVGK 408
G ++ + +W ++ + N L+ + + G
Sbjct 327 LRGRLQEELRGRLLAYKLQWNQGGESQDPLLFKENVAHLSGAGRFFNATFQVAACTMAGC 386
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
+ + PV ++A + +WV
Sbjct 387 GPWSQPVL-------VMPVSAMQAQTQRGHMWV 412
Score = 76.0 bits (185), Expect = 1e-12, Method: Composition-based stats.
Identities = 56/396 (14%), Positives = 115/396 (29%), Gaps = 65/396 (16%)
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
A+G EV ++T + + L V N+ RN G S + T+
Sbjct 140 ASGPPEPVEVLWWLGGEQNGDFTPSPSVLFVKGVNESIKFHCEPRNARGISVSRTGTV-- 197
Query 419 CDFQATHPVMDLKAFPKDNM-LWVEWTT-----PRESVKKYILEWCVLSDKAPCITDWQQ 472
+A + + + + W+ + S L + D
Sbjct 198 -HIKARPDSLGRTGHHVSDFNITLTWSPGFTGHSQLSTCTIQL---SRGPGEVKLPDVVV 253
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY-LKQAPPSKGPTVRTKKVG 531
E ++ L Y + V G + QA PS P T +
Sbjct 254 EVPPFQ--HVFEGLRSYSNYSVRVRCDNEVGSSPFSPWVDFHTPQAAPSAAPKNFTFDLS 311
Query 532 KNEAVLEWDQLPVDVQNGFIRN--------YTIFYRTIIGNETAVNVDSSHTEYTLSSLT 583
+ + L W L + G ++ Y + + ++ + + ++ L+
Sbjct 312 EQQLTLSWATLEQEELRGRLQEELRGRLLAYKLQWNQGGESQDPLLFKEN-----VAHLS 366
Query 584 SDTLY---MVRMAAYTDEGGKDGPEFTFTTPK---FAQGEIEAIVVPVCLAFLLTTLLGV 637
+ ++AA T G + P AQ + + V + L+ T++G+
Sbjct 367 GAGRFFNATFQVAACTMAGCGPWSQPVLVMPVSAMQAQTQRGHMWVGLLFGLLVATMVGL 426
Query 638 LFCFNKRDLIKKH-------------------------IWPNVPDPS------KSHIAQW 666
L R+ K+ +P +P+ + S +
Sbjct 427 LLIVLIRNRGKETQFGSAFAAQGAEVPVSFTAARSFNRQFPELPESTLDSLGINSDLKAK 486
Query 667 SPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKK 702
+ +M G F V +++ +
Sbjct 487 LQDVLIFERLLTLGRMLGKGEFGSVREAFLKSENNS 522
>sp|P13596|NCAM1_RAT Neural cell adhesion molecule 1 OS=Rattus
norvegicus OX=10116 GN=Ncam1 PE=1 SV=1
Length=858
Score = 93.0 bits (229), Expect = 6e-18, Method: Composition-based stats.
Identities = 58/394 (15%), Positives = 122/394 (31%), Gaps = 38/394 (10%)
Query 386 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT 445
++T + ND T N +G+ + + A + P + V++
Sbjct 476 EVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDR---VEPYSSTAQVQFDE 532
Query 446 PRE----SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
P + KY EW L ++A + ++ + L Y + + +
Sbjct 533 PEATGGVPILKYKAEWKSLGEEAWHSKWYDAKEANMEGIVTIMGLKPETRYAVRLAALNG 592
Query 502 DGPGS-PESIKAYLKQAPPSKGPTVRTKK-VGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
G G + + + P + + N + + D IR+Y + YR
Sbjct 593 KGLGEISAATEFKTQPVREPSAPKLEGQMGEDGNSIKVN--LIKQDDGGSPIRHYLVKYR 650
Query 560 TIIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT-------- 610
+ + + S L SL + Y V + A +G F F T
Sbjct 651 ALASEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIP 710
Query 611 ----PKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQW 666
P + + + + LL ++ + F + + I + + +
Sbjct 711 ANGSPTAGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCI-------AVNLCGKA 763
Query 667 SPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLK------SLDLFKKEKIN 720
P + K D + + V E ++ P + K + L + EK
Sbjct 764 GPGAKGKDMEEGKAAFSKDESKEPIVEVRTEE-ERTPNHDGGKHTEPNETTPLTEPEKGP 822
Query 721 TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTS 754
E S + + + ++ ++ +N S
Sbjct 823 VETKSEPQESEAKPAPTEVKTVPNEATQTKENES 856
Score = 91.5 bits (225), Expect = 2e-17, Method: Composition-based stats.
Identities = 70/431 (16%), Positives = 123/431 (29%), Gaps = 64/431 (15%)
Query 44 FTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQY--------------TIINRTASSV 89
T C + I W+T+ I E+ ++ R+ + V
Sbjct 326 VTLTC-------EASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARV 378
Query 90 TFTDIASLNIQLTCNILT-----FGQLEQNVYGITIISGLPPE--KPKNLSCIVNEGKKM 142
+ + S+ + GQ Q++Y + P+ P + +
Sbjct 379 SSLTLKSIQYTDAGEYICTASNTIGQDSQSMY---LEVQYAPKLQGPVAVYTWEGNQVNI 435
Query 143 RCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN 202
C E + T+ Y+T +EV ++EN
Sbjct 436 TC------EVFAYPSATISWFRDGQLLPSSNYSN------IKIYNTPSASYLEVTPDSEN 483
Query 203 ALGKVTSDHINFDPVYK-----VKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILK 256
G +N V+ + P + S+ E SS ++ + P ILK
Sbjct 484 DFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILK 543
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSS-FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y ++++ W + + T+ LKP T Y R+ + G G S +E
Sbjct 544 YKAEWKSLGEEAWHSKWYDAKEANMEGIVTIMGLKPETRYAVRLAALNGKGLGEISAATE 603
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT---- 371
T R AP ++ + + I Y V
Sbjct 604 ---FKTQPVREPSAPKLEGQMGEDGNSIKVNLI------KQDDGGSPIRHYLVKYRALAS 654
Query 372 RWKSHLQNYTVNATKLTVNLT-NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
WK ++ + + + +L N Y + N GKS AA P
Sbjct 655 EWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGS 714
Query 431 KAFPKDNMLWV 441
V
Sbjct 715 PTAGLSTGAIV 725
>sp|Q02092|GHR_CHICK Growth hormone receptor OS=Gallus gallus
OX=9031 GN=GHR PE=1 SV=1
Length=608
Score = 91.8 bits (226), Expect = 8e-18, Method: Composition-based stats.
Identities = 40/196 (20%), Positives = 72/196 (37%), Gaps = 20/196 (10%)
Query 129 PKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAK-RDTPTSCTVDYS 187
P+ C E + C W G+ T T L + + + +C SC + S
Sbjct 29 PQISKCRSPELETFSCYWTDGKVTTSGTIQLLYMKRSDEDWKECPDYITAGENSCYFNTS 88
Query 188 -TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS----ILKL 242
T ++ V + N D F V P+PP +L+ + +++
Sbjct 89 YTSIWIPYCVKL--ANK--DEVFDEKCFSVDEIVLPDPPVHLNWTLLNTSQTGIHGDIQV 144
Query 243 TWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
W P V I L+Y +QY+ + + W ++ P + + LK +Y R
Sbjct 145 RWDPPPTADVQKGWITLEYELQYKEVNETKWKELEPRL----STVVPLYSLKMGRDYEIR 200
Query 299 IRCMKEDG--KGYWSD 312
+R + G +S+
Sbjct 201 VRSRQRTSEKFGEFSE 216
Score = 59.9 bits (143), Expect = 7e-08, Method: Composition-based stats.
Identities = 66/329 (20%), Positives = 109/329 (33%), Gaps = 46/329 (14%)
Query 519 PSKGPTVRTKKVGKNE------AVLEWDQLP-VDVQNGFIR-NYTIFYRTIIGNETAVNV 570
P + + ++ + WD P DVQ G+I Y + Y+ + +
Sbjct 120 PDPPVHLNWTLLNTSQTGIHGDIQVRWDPPPTADVQKGWITLEYELQYKEVNETKWKELE 179
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA------IVVP 624
T L SL Y +R+ + K G F Q IE I P
Sbjct 180 PRLSTVVPLYSLKMGRDYEIRVRSRQRTSEKFGEFSEILYVSFTQAGIEFVHCAEEIEFP 239
Query 625 VCLAFLLTT----LLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF---- 676
L + + +L +K+ +K I+P VP P I P +
Sbjct 240 WFLVVVFGVCGLAVTAILILLSKQPRLKMLIFPPVPVP---KIKGIDPDLLKKGKLDEVN 296
Query 677 -------NSKDQMYSDGNFTDVSVVEIEANDKKPFPED---LKSLDLFKKEKINTEGHSS 726
N K Q+Y+D + + ++I+ +D+K D L S D K
Sbjct 297 SILASHDNYKTQLYNDDLWVEFIELDIDDSDEKNRVSDTDRLLSDDHLKSHSCLGAKDDD 356
Query 727 GIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSG-------YRHQVPSVQVFSR 779
G +SC P S +++ S Q+ V + V ++Q +
Sbjct 357 S-GRASCYEPDIPETDFS-ASDTCDAISDIDQFKKVTEKEEDLLCLHRKDDVEALQSLAN 414
Query 780 SESTQP--LLDSEERPEDLQLVDHVDGGD 806
+++ QP SE R D D +
Sbjct 415 TDTQQPHTSTQSESRESWPPFADSTDSAN 443
Score = 39.1 bits (89), Expect = 0.21, Method: Composition-based stats.
Identities = 25/178 (14%), Positives = 45/178 (25%), Gaps = 16/178 (9%)
Query 333 WYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT----KLT 388
W +I + T W +G I + + R + T
Sbjct 28 WPQISKCRSPELETFSCYWTDG-KVTTSGTIQ--LLYMKRSDEDWKECPDYITAGENSCY 84
Query 389 VNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM-------LWV 441
N + V+ + P + L + + V
Sbjct 85 FNTSYTSIWIPYCVKLANKDEVFDEKCFSVDEIVLPDPPVHLNWTLLNTSQTGIHGDIQV 144
Query 442 EWTTPR--ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
W P + K +I L K T W++ + + +L + Y I V
Sbjct 145 RWDPPPTADVQKGWITLEYELQYKEVNETKWKELEPRLSTVVPLYSLKMGRDYEIRVR 202
>sp|P54761|EPHB4_MOUSE Ephrin type-B receptor 4 OS=Mus musculus
OX=10090 GN=Ephb4 PE=1 SV=2
Length=987
Score = 92.6 bits (228), Expect = 9e-18, Method: Composition-based stats.
Identities = 35/198 (18%), Positives = 63/198 (32%), Gaps = 21/198 (11%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDK-------APCITDWQQEDG 475
+ + L +EW+ P ES + L + V + PC D + G
Sbjct 323 PPSAPRSVVHHLNGSTLRLEWSAPLESGGREDLTYAVRCRECRPGGSCLPCGGDMTFDPG 382
Query 476 ----TVHRTYLRGNLAESKCYLITVTPVYA-----DGPGSPESIKAYLKQAPPSKGPTVR 526
+RG L Y V + GP E + + P +R
Sbjct 383 PRDLVEPWVAIRG-LRPDVTYTFEVAALNGVSTLATGPPPFEPVNVTTDREVPPAVSDIR 441
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSHTEYTLSSLTS 584
+ + +L W +G + +Y + Y G + + +S L L
Sbjct 442 VTRSSPSSLILSWAI--PRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAELRGLKR 499
Query 585 DTLYMVRMAAYTDEGGKD 602
Y+V++ A ++ G
Sbjct 500 GASYLVQVRARSEAGYGP 517
Score = 86.4 bits (212), Expect = 8e-16, Method: Composition-based stats.
Identities = 42/202 (21%), Positives = 70/202 (35%), Gaps = 18/202 (9%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCKAKR--- 176
PP P+++ +N G +R EW GGRE + C
Sbjct 323 PPSAPRSVVHHLN-GSTLRLEWSAPLESGGREDLTYAVRCRECRPGGS-CLPCGGDMTFD 380
Query 177 DTPTSCTVDYSTVY----FVNIEVWVEAENALGKVTSDHINFDPVYKVKPN--PPHNLSV 230
P + + V V A N + + + F+PV PP +
Sbjct 381 PGPRDLVEPWVAIRGLRPDVTYTFEVAALNGVSTLATGPPPFEPVNVTTDREVPPAVSDI 440
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ S L L+W P S +L Y ++Y K A S + ++ + ++ LK
Sbjct 441 RVTRSSPSSLILSWAIPRAPSGAVLDYEVKYHEKGAEGPSSVR--FLKTSENRAELRGLK 498
Query 291 PFTEYVFRIRCMKEDGKGYWSD 312
Y+ ++R E G G +
Sbjct 499 RGASYLVQVRARSEAGYGPFGQ 520
Score = 67.6 bits (163), Expect = 5e-10, Method: Composition-based stats.
Identities = 37/231 (16%), Positives = 66/231 (29%), Gaps = 27/231 (12%)
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTK 264
+ SD + P+ P ++ V + S L+L W+ P L Y ++ R
Sbjct 310 RARSDPRS--SPCTTPPSAPRSV-VHHLNG--STLRLEWSAPLESGGREDLTYAVRCREC 364
Query 265 DAST-------WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK-GYWSDWSEE 316
P ++ L+P Y F + + E
Sbjct 365 RPGGSCLPCGGDMTFDPGPRDLVEPWVAIRGLRPDVTYTFEVAALNGVSTLATGPPPFEP 424
Query 317 ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
+ T + P I + + ++ L W P +G +LDYEV +
Sbjct 425 VNVTTDREVP----PAVSDIRVTRSS-PSSLILSW--AIPRAPSGAVLDYEVKYHEKGAE 477
Query 377 LQNY------TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+ + N +L YL + R+ G
Sbjct 478 GPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQL 528
Score = 61.8 bits (148), Expect = 3e-08, Method: Composition-based stats.
Identities = 31/208 (15%), Positives = 53/208 (25%), Gaps = 28/208 (13%)
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
P P + H G T++L W + P + L Y V +
Sbjct 315 PRSSPCTTPPSAPRSVVHHLNGS-TLRLEW-SAPLESGGREDLTYAVRCRECRPGGSCLP 372
Query 382 VNA-------------TKLTVNLTNDR--YLATLTVRNLVGK---SDAAVLTIPACDFQA 423
+ + Y + N V + +
Sbjct 373 CGGDMTFDPGPRDLVEPWVAIRGLRPDVTYTFEVAALNGVSTLATGPPPFEPVNVTTDRE 432
Query 424 THPVMD--LKAFPKDNMLWVEW---TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
P + + L + W P +V Y +++ + P + +
Sbjct 433 VPPAVSDIRVTRSSPSSLILSWAIPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSEN-- 490
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGS 506
R LRG L YL+ V G G
Sbjct 491 RAELRG-LKRGASYLVQVRARSEAGYGP 517
>sp|Q02858|TIE2_MOUSE Angiopoietin-1 receptor OS=Mus musculus
OX=10090 GN=Tek PE=1 SV=2
Length=1122
Score = 92.6 bits (228), Expect = 9e-18, Method: Composition-based stats.
Identities = 48/306 (16%), Positives = 94/306 (31%), Gaps = 13/306 (4%)
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTV----RNLVGKSDA 411
P+ +G I ++ + V T+N R L V G+
Sbjct 469 PYFGDGPIKSKKLFYKPVNQAWKYIEVTNEIFTLNYLEPRTDYELCVQLARPGEGGEGHP 528
Query 412 AVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTP-RESVKKYILEWCVLSDKAPCITD 469
+ P L PK L + W S ++ +E S +
Sbjct 529 GPVRRFTTASIGLPPPRGLSLLPKSQTALNLTWQPIFTNSEDEFYVEVERRSLQTTSDQQ 588
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL-KQAPPSKGPTVRTK 528
+ G + L NL + Y + E ++A+ P + ++
Sbjct 589 NIKVPGNLTSVLL-SNLVPREQYTVRARVNTKAQGEWSEELRAWTLSDILPPQPENIKIS 647
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLY 588
+ + A++ W + + I Y + + + +++ T+Y L L +T Y
Sbjct 648 NITDSTAMVSWTIVDGYSISSIIIRYKVQGKNEDQHIDVKIKNATVTQYQLKGLEPETTY 707
Query 589 MVRMAAYTDEGGK-DGPEFTFTTPKFAQGEIEAIVVPVCLAFLLT----TLLGVLFCFNK 643
V + A + G T + + + L +L T + VL F
Sbjct 708 HVDIFAENNIGSSNPAFSHELRTLPHSPASADLGGGKMLLIAILGSAGMTCITVLLAFLI 767
Query 644 RDLIKK 649
+K+
Sbjct 768 MLQLKR 773
Score = 77.2 bits (188), Expect = 5e-13, Method: Composition-based stats.
Identities = 41/204 (20%), Positives = 69/204 (34%), Gaps = 17/204 (8%)
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
F P PP LS++ + + L LTW S ++ R+ ++ Q
Sbjct 534 FTTASIGLP-PPRGLSLLPKSQ--TALNLTWQPIFTNSEDEFYVEVERRSLQTTSDQQNI 590
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
+S + +L P +Y R R + +WSEE T D P
Sbjct 591 --KVPGNLTSVLLSNLVPREQYTVRARVNTKAQ----GEWSEELRAWTLSDILPPQPENI 644
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL-- 391
+ + + T + W + + + I+ Y+V H+ NAT L
Sbjct 645 KISNITDS----TAMVSWTIVDGYSISSIIIRYKVQGKNEDQHIDVKIKNATVTQYQLKG 700
Query 392 --TNDRYLATLTVRNLVGKSDAAV 413
Y + N +G S+ A
Sbjct 701 LEPETTYHVDIFAENNIGSSNPAF 724
Score = 70.7 bits (171), Expect = 5e-11, Method: Composition-based stats.
Identities = 38/215 (18%), Positives = 70/215 (33%), Gaps = 17/215 (8%)
Query 118 ITIISGLPPEKPKNLSCIVNEGKKMRCEWDG---GRETHLETNFTLKSEWATHKFADCKA 174
T GLPP P+ LS + + W E +S T +
Sbjct 535 TTASIGLPP--PRGLSLLPKSQTALNLTWQPIFTNSEDEFYVEVERRSLQTTSDQQNI-- 590
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
K + + + V V S+ + + + P P N+ + N
Sbjct 591 KVPGNLTSVLLSNLVPREQYTVRARVNTKAQGEWSEELRAWTLSDILPPQPENIKISNIT 650
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ ++++ T + S II++Y +Q + +D I + +T + + ++ L+P T
Sbjct 651 DSTAMVSWTIVDGYSISSIIIRYKVQGKNED----QHIDVKIKNATVTQYQLKGLEPETT 706
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
Y I G S A P
Sbjct 707 YHVDIFAENNIGS------SNPAFSHELRTLPHSP 735
>sp|P10912|GHR_HUMAN Growth hormone receptor OS=Homo sapiens OX=9606
GN=GHR PE=1 SV=1
Length=638
Score = 91.8 bits (226), Expect = 1e-17, Method: Composition-based stats.
Identities = 41/212 (19%), Positives = 81/212 (38%), Gaps = 30/212 (14%)
Query 128 KPKNLSCIVNEGKKMRCEW---------DGGRETHLETNFTLKSEWATHKFADCKAK-RD 177
+PK C E + C W + G T ++ T ++ +C
Sbjct 50 EPKFTKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTR--RNTQEWTQEWKECPDYVSA 107
Query 178 TPTSCTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS----VIN 232
SC + S ++ + + + T D F V+P+PP L+ ++
Sbjct 108 GENSCYFNSSFTSIWIPYCIKLTSNGG----TVDEKCFSVDEIVQPDPPIALNWTLLNVS 163
Query 233 SEELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
+ + +++ W P + ++L+Y +QY+ + + W + P T +S V
Sbjct 164 LTGIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILT----TSVPVYS 219
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
LK EY R+R + + G + ++SE
Sbjct 220 LKVDKEYEVRVRSKQRNS-GNYGEFSEVLYVT 250
Score = 59.1 bits (141), Expect = 1e-07, Method: Composition-based stats.
Identities = 67/382 (18%), Positives = 124/382 (32%), Gaps = 56/382 (15%)
Query 447 RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
R + +++ EW D + + + ++ Y I +T
Sbjct 88 RRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWI--------PYCIKLTSNGGTVDEK 139
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKN----EAVLEWDQLP-VDVQNG-FIRNYTIFYRT 560
S+ ++ PP V + + W+ D+Q G + Y + Y+
Sbjct 140 CFSVDEIVQPDPPIAL-NWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQYKE 198
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA--YTDEGGKDGPE-FTFTTPKFAQGE 617
+ + + T + SL D Y VR+ + + E T P+ +Q
Sbjct 199 VNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMSQFT 258
Query 618 IEA-----IVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPP 672
E ++ + T++ +F F+K+ IK I P VP P I P
Sbjct 259 CEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPPVPVP---KIKGIDPDLLK 315
Query 673 RHNFNS-----------KDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINT 721
K + +SD ++ + ++I+ D+K D L EK ++
Sbjct 316 EGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEESDTDRLLSSDHEKSHS 375
Query 722 EGHSSGIGGSSCMSSSRPSISSS--DENESSQNTSSTVQYSTVVH--------------S 765
G S S P I + + N+ + TS Q + S
Sbjct 376 NLGVKD-GDSGRTSCCEPDILETDFNANDIHEGTSEVAQPQRLKGEADLLCLDQKNQNNS 434
Query 766 GYRHQVPSVQV--FSRSESTQP 785
Y P+ Q ++E +P
Sbjct 435 PYHDACPATQQPSVIQAEKNKP 456
Score = 38.7 bits (88), Expect = 0.27, Method: Composition-based stats.
Identities = 31/205 (15%), Positives = 61/205 (30%), Gaps = 25/205 (12%)
Query 312 DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW--KTLPPFEANGKI------ 363
WS ++ + SK P F + T W + + G I
Sbjct 33 PWSLQSVNPGLKTNSSKEPKF----TKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTR 88
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVR--NLVGKSDAAVLTIPACDF 421
+ + WK + N + ++ + G D ++
Sbjct 89 RNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIPYCIKLTSNGGTVDEKCFSV-DEIV 147
Query 422 QATHPV------MDLKAFPKDNMLWVEWTTPRESVKKY---ILEWCVLSDKAPCITDWQQ 472
Q P+ +++ + V W PR + + +LE+ + K T W+
Sbjct 148 QPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQY-KEVNETKWKM 206
Query 473 EDGTVHRTYLRGNLAESKCYLITVT 497
D + + +L K Y + V
Sbjct 207 MDPILTTSVPVYSLKVDKEYEVRVR 231
>sp|Q14213|IL27B_HUMAN Interleukin-27 subunit beta OS=Homo sapiens
OX=9606 GN=EBI3 PE=1 SV=2
Length=229
Score = 86.8 bits (213), Expect = 1e-17, Method: Composition-based stats.
Identities = 44/209 (21%), Positives = 79/209 (38%), Gaps = 21/209 (10%)
Query 125 PPEK---PKNLSCI-VNEGKKMRCEWD--GGRETHLETNFTLKSEWAT---HKFADCKAK 175
PP P+ + C + C W + +F C +
Sbjct 24 PPAALTLPR-VQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQ 82
Query 176 RDTPTSCTV-DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
T TSCT+ D + V A + G +S + F + +KP+PP + +
Sbjct 83 TPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSF-VPFITEHIIKPDPPEGVRLSPLA 141
Query 235 ELSSILKLTWTNPS---IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
E L++ W P + LKY I+Y+ + A+ + ++ P + +SF ++ ++P
Sbjct 142 E--RQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEA----TSFILRAVRP 195
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
Y ++ G SDWS A+
Sbjct 196 RARYYVQVAAQDLTDYGELSDWSLPATAT 224
Score = 52.9 bits (125), Expect = 3e-06, Method: Composition-based stats.
Identities = 37/196 (19%), Positives = 60/196 (31%), Gaps = 21/196 (11%)
Query 408 KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES--------VKKYILEWCV 459
K A LT+P +A+ + + WT P + Y L
Sbjct 22 KGPPAALTLPRVQCRASRYPIAVDC---------SWTLPPAPNSTSPVSFIATYRLGMAA 72
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
PC+ QQ + T L Y++ VT V+ G S P
Sbjct 73 RGHSWPCL---QQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKP 129
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPV-DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
VR + + + ++W+ F Y I Y+ T +
Sbjct 130 DPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFI 189
Query 579 LSSLTSDTLYMVRMAA 594
L ++ Y V++AA
Sbjct 190 LRAVRPRARYYVQVAA 205
Score = 41.0 bits (94), Expect = 0.025, Method: Composition-based stats.
Identities = 22/172 (13%), Positives = 46/172 (27%), Gaps = 12/172 (7%)
Query 350 VWKTLPPFEANGK---ILDYEVTLTRWKSHLQNYTVNATKLTVNLTN------DRYLATL 400
W P + I Y + + T + +T+ Y+ +
Sbjct 47 SWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNV 106
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI--LEWC 458
T + G S + V I + P + + L V+W P I L++
Sbjct 107 TAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYW 166
Query 459 VLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
+ + + +++ + Y + V G
Sbjct 167 IRYKRQGAARF-HRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDW 217
>sp|Q03145|EPHA2_MOUSE Ephrin type-A receptor 2 OS=Mus musculus
OX=10090 GN=Epha2 PE=1 SV=3
Length=977
Score = 92.2 bits (227), Expect = 1e-17, Method: Composition-based stats.
Identities = 47/211 (22%), Positives = 85/211 (40%), Gaps = 23/211 (11%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHKFADCKAKRDTPTSC 182
PP P L+ I K + W ++T + +++ E + +C +
Sbjct 329 PPSAPNYLTAIGMGAK-VELRWTAPKDTGGRQDIVYSVTCEQCWPESGECGPCEASVRYS 387
Query 183 TVDYSTVY----------FVNIEVWVEAENAL-GKVTSDHINFDPVYKVKPNPPHNLSVI 231
++ +N VEA N + G VTS V + PP V
Sbjct 388 EPPHALTRTSVTVSDLEPHMNYTFAVEARNGVSGLVTSRSFRTASVSINQTEPP---KVR 444
Query 232 NSEELSSILKLTWTNPSIKSVIILKYNIQYRTK-DASTWSQIPPEDTASTRSSFTVQDLK 290
+ ++ L +TW+ P + + KY + YR K DA++++ E S T+ DL
Sbjct 445 LEDRSTTSLSVTWSIPVSQQSRVWKYEVTYRKKGDANSYNVRRTEGF-----SVTLDDLA 499
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
P T Y+ +++ + ++G+G S E + T
Sbjct 500 PDTTYLVQVQALTQEGQGAGSKVHEFQTLST 530
Score = 85.7 bits (210), Expect = 1e-15, Method: Composition-based stats.
Identities = 38/214 (18%), Positives = 68/214 (32%), Gaps = 15/214 (7%)
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV-----LSDKAPC---- 466
+ + L A + + WT P+++ + + + V + C
Sbjct 322 LSMSCTRPPSAPNYLTAIGMGAKVELRWTAPKDTGGRQDIVYSVTCEQCWPESGECGPCE 381
Query 467 -ITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVYA-DGPGSPESIKAYLKQAPPSKGP 523
+ + + RT +L Y V G + S + ++ P
Sbjct 382 ASVRYSEPPHALTRTSVTVSDLEPHMNYTFAVEARNGVSGLVTSRSFRTASVSINQTEPP 441
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLT 583
VR + + W +PV Q + Y + YR + + TL L
Sbjct 442 KVRLEDRSTTSLSVTWS-IPVSQQ-SRVWKYEVTYRKKGDANSYNVRRTEGFSVTLDDLA 499
Query 584 SDTLYMVRMAAYTDEGGKDGPEF-TFTTPKFAQG 616
DT Y+V++ A T EG G + F T
Sbjct 500 PDTTYLVQVQALTQEGQGAGSKVHEFQTLSTEGS 533
Score = 52.9 bits (125), Expect = 2e-05, Method: Composition-based stats.
Identities = 39/213 (18%), Positives = 69/213 (32%), Gaps = 27/213 (13%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNI----------QYRT 263
DP+ PP + + + + + ++L WT P + Y++ +
Sbjct 320 DPLSMSCTRPPSAPNYLTAIGMGAKVELRWTAPKDTGGRQDIVYSVTCEQCWPESGECGP 379
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+AS PP TR+S TV DL+P Y F + S AS +
Sbjct 380 CEASVRYSEPPHAL--TRTSVTVSDLEPHMNYTFAVEARNGVSGLVTSRSFRTASVSINQ 437
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN 383
P P + + ++ + W P ++ YEVT +
Sbjct 438 TEP---PKVRLE-----DRSTTSLSVTWSI--PVSQQSRVWKYEVTYRKKGDANSYNVRR 487
Query 384 ATKLTVNL----TNDRYLATLTVRNLVGKSDAA 412
+V L + YL + G+ +
Sbjct 488 TEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGS 520
>sp|Q06807|TIE2_BOVIN Angiopoietin-1 receptor OS=Bos taurus OX=9913
GN=TEK PE=2 SV=1
Length=1125
Score = 92.2 bits (227), Expect = 1e-17, Method: Composition-based stats.
Identities = 57/308 (19%), Positives = 101/308 (33%), Gaps = 15/308 (5%)
Query 356 PFEANGKILDYEVTLTRWKSH--LQNYTVNATKLTVNLTNDRYLATLTV----RNLVGKS 409
P+ +G I ++ + ++ V +T+N R L V R G+
Sbjct 469 PYFGDGPIKSKKLLYKPVNHYEAWRHIQVTNEIVTLNYLEPRTEYELCVQLVRRGEGGEG 528
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTP-RESVKKYILEWCVLSDKAPCI 467
+ P L PK L + W S + +E S +
Sbjct 529 HPGPVRRFTTASIGLPPPRGLSLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQMNSD 588
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVT-PVYADGPGSPESIKAYLKQAPPSKGPTVR 526
+ G + L NL + Y++ A G S + I L P + ++
Sbjct 589 QQNIKVPGNLTSVLL-NNLHPREQYIVRARVNTKAQGEWSEDLIAWTLSDIVPPQPENIK 647
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDT 586
+ + AV+ W L + I Y + + + +++ T+Y L L T
Sbjct 648 IFNITDSSAVISWTILDGYSISAIIIRYKVQGKNEDQHIDVKIKNATITQYQLKGLEPQT 707
Query 587 LYMVRMAAYTDEGGK-DGPEFTFTTPKFAQGEIEAIVVPVCLAFLLT----TLLGVLFCF 641
+Y V + A + G TT +Q + + L +L T L VL F
Sbjct 708 VYQVDIFAENNIGSSNPTSSHELTTLSESQAPADLGGRKMLLIAILGSAGMTCLTVLLAF 767
Query 642 NKRDLIKK 649
+K+
Sbjct 768 LIMLQLKR 775
Score = 79.1 bits (193), Expect = 1e-13, Method: Composition-based stats.
Identities = 50/314 (16%), Positives = 101/314 (32%), Gaps = 43/314 (14%)
Query 35 SPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDI 94
V+ NF + + E + + +++K P Y + I
Sbjct 451 PKVIDTGHNFAVINISSEPYFGDGPIKSKKLLYK------PVNHYE---------AWRHI 495
Query 95 ASLNIQLTCNILTFGQLEQNVYG------------------ITIISGLPPEKPKNLSCIV 136
N +T N L + T GLPP P+ LS +
Sbjct 496 QVTNEIVTLNYLEPRTEYELCVQLVRRGEGGEGHPGPVRRFTTASIGLPP--PRGLSLLP 553
Query 137 NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY-FVNIE 195
+ W + + + + +D + + +V + ++
Sbjct 554 KSQTTLNLTWQPIFPSSEDDFYVEVERRSVQMNSDQQNIKVPGNLTSVLLNNLHPREQYI 613
Query 196 VWVEAEN-ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
V A G+ + D I + V P P N+ + N + S+++ +WT + I
Sbjct 614 VRARVNTKAQGEWSEDLIAWTLSDIVPPQ-PENIKIFNITDSSAVI--SWT--ILDGYSI 668
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
I+Y+ + + I + +T + + ++ L+P T Y I G S
Sbjct 669 SAIIIRYKVQGKNEDQHIDVKIKNATITQYQLKGLEPQTVYQVDIFAENNIGSSNP-TSS 727
Query 315 EEASGITYEDRPSK 328
E + ++ P+
Sbjct 728 HELTTLSESQAPAD 741
Score = 73.7 bits (179), Expect = 7e-12, Method: Composition-based stats.
Identities = 40/218 (18%), Positives = 72/218 (33%), Gaps = 17/218 (8%)
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
F P PP LS++ + + L LTW S ++ R+ ++ Q
Sbjct 536 FTTASIGLP-PPRGLSLLPKSQ--TTLNLTWQPIFPSSEDDFYVEVERRSVQMNSDQQNI 592
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
+S + +L P +Y+ R R + +WSE+ T D P
Sbjct 593 --KVPGNLTSVLLNNLHPREQYIVRARVNTKAQ----GEWSEDLIAWTLSDIVPPQPENI 646
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN 393
+ + + + + W L + + I+ Y+V H+ NAT L
Sbjct 647 KIFNITDS----SAVISWTILDGYSISAIIIRYKVQGKNEDQHIDVKIKNATITQYQLKG 702
Query 394 ----DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
Y + N +G S+ ++ P
Sbjct 703 LEPQTVYQVDIFAENNIGSSNPTSSHELTTLSESQAPA 740
>sp|O73878|EPB4B_DANRE Ephrin type-B receptor 4b OS=Danio rerio
OX=7955 GN=ephb4b PE=1 SV=2
Length=976
Score = 91.8 bits (226), Expect = 1e-17, Method: Composition-based stats.
Identities = 51/308 (17%), Positives = 103/308 (33%), Gaps = 36/308 (12%)
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
+ + + D ++ +EW+ P + + L + V Q D
Sbjct 321 SACTKPPSAPRSIIYQINDTVVTLEWSEPLDRGGRSDLSYSVECMHCRGSLCVQCADSIT 380
Query 478 HR---------TYLRGNLAESKCYLITVTPVYADG-----PGSPESIKAYLKQAPPSKGP 523
+R + L Y TV + S+ +
Sbjct 381 YRPGQMGVPGRRVIIRGLLPHTTYTFTVLAQNGVSAVSHTSPASSSVNITTSRDVAVPVS 440
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLT 583
+R K ++ + W +P Q+ I++Y + Y ++ V S + L+ L+
Sbjct 441 GIRRIKASESSVSISWT-VPPQTQHS-IQDYQLRYSLKGQDDGWQYVSSRSSSVVLNDLS 498
Query 584 SDTLYMVRMAAYTDEGGKD-GPEFTFTTP-----KFAQGEIEAIVVPVCLAFLLTTLLGV 637
+ Y V++ A T G + +T ++ + ++V + L L+ ++
Sbjct 499 RASQYQVQVRARTAAGYGHFSSAVSISTLPDDEESPSRLMLTGVLVAIGLLILIAVVIVA 558
Query 638 LFCFNKRDLIKKHIWPNVPDPSKSHIAQWS------PHTPPRHNFNSKDQMYSDGNFTDV 691
+FCF + + PDP KS Q+ + P + + + DV
Sbjct 559 VFCFRRSTRRRD------PDPDKS--GQFLMGQGIKVYIDPFTYEDPNEAVREFAKEIDV 610
Query 692 SVVEIEAN 699
S V+IE
Sbjct 611 SFVKIEEV 618
Score = 89.1 bits (219), Expect = 9e-17, Method: Composition-based stats.
Identities = 39/221 (18%), Positives = 77/221 (35%), Gaps = 25/221 (11%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRE--THLETNFTLKSEWA-THKFADC-------K 173
PP P+++ +N+ + EW + + +++++ C
Sbjct 325 KPPSAPRSIIYQIND-TVVTLEWSEPLDRGGRSDLSYSVECMHCRGSLCVQCADSITYRP 383
Query 174 AKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT-----SDHINFDPVYKVKPNPPHNL 228
+ P + + V A+N + V+ S +N V
Sbjct 384 GQMGVPGRRVIIRGLLPHTTYTFTVLAQNGVSAVSHTSPASSSVNITTSRDVAVPVSGIR 443
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK-DASTWSQIPPEDTASTRSSFTVQ 287
+ SE S + ++WT P I Y ++Y K W +S SS +
Sbjct 444 RIKASE---SSVSISWTVPPQTQHSIQDYQLRYSLKGQDDGWQ-----YVSSRSSSVVLN 495
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
DL ++Y ++R G G++S ++ E+ PS+
Sbjct 496 DLSRASQYQVQVRARTAAGYGHFSSAVSISTLPDDEESPSR 536
Score = 65.6 bits (158), Expect = 2e-09, Method: Composition-based stats.
Identities = 45/309 (15%), Positives = 85/309 (28%), Gaps = 41/309 (13%)
Query 149 GRETHLETNFT-LKSEWATHKFADCKAKRDT----PTSCTVDYSTVYFVNIE---VWVEA 200
G+ T T F +W + C K C Y ++ V
Sbjct 233 GQSTAPPTMFCGEDGQWVGPPSSTCACKPGYEPVDSDRCRACGLGQYKASVGGSLCRVCP 292
Query 201 ENALGKVTSDHINF----------DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+N+ + D PP I + +++ L W+ P +
Sbjct 293 DNSNTHFAGSSLCVCRPGYHRATSDLPDSACTKPPSAPRSIIYQINDTVVTLEWSEPLDR 352
Query 251 SVII-LKYNIQYRTKDAS------TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
L Y+++ S P ++ L P T Y F +
Sbjct 353 GGRSDLSYSVECMHCRGSLCVQCADSITYRPGQMGVPGRRVIIRGLLPHTTYTFTVLAQN 412
Query 304 EDGK-GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
+ S S + T D +V + W P +
Sbjct 413 GVSAVSHTSPASSSVNITTSRDVAVPVSGIRRI-----KASESSVSISWTVPPQTQH--S 465
Query 363 ILDYEVTLT--RWKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNLVG----KSDAAVL 414
I DY++ + Q + ++ + +N + +Y + R G S ++
Sbjct 466 IQDYQLRYSLKGQDDGWQYVSSRSSSVVLNDLSRASQYQVQVRARTAAGYGHFSSAVSIS 525
Query 415 TIPACDFQA 423
T+P +
Sbjct 526 TLPDDEESP 534
>sp|P0C0K6|EPHB6_PANTR Ephrin type-B receptor 6 OS=Pan troglodytes
OX=9598 GN=EPHB6 PE=3 SV=4
Length=1020
Score = 91.8 bits (226), Expect = 2e-17, Method: Composition-based stats.
Identities = 41/225 (18%), Positives = 70/225 (31%), Gaps = 27/225 (12%)
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKY-----ILEWCVLSDKAP----------C 466
+L + + L + W PRE + ++ + P C
Sbjct 367 GPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCRRC 426
Query 467 ITDWQQED---GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYLKQAP 518
+ + G L G L Y++ V V SP+ I
Sbjct 427 RDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEV 486
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEY 577
PS P V N + W Q D NG I +Y + +Y + + + S
Sbjct 487 PSAVPVVHQVSRASNSITVSWPQ--PDQTNGNILDYQLRYYDQVEDESHSFTLTSETNTA 544
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAI 621
T++ L+ +Y ++ A T G G + F T + +
Sbjct 545 TVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLP 589
Score = 89.5 bits (220), Expect = 8e-17, Method: Composition-based stats.
Identities = 42/211 (20%), Positives = 69/211 (33%), Gaps = 31/211 (15%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATH-------KFADC 172
PP P+ L V +G + W GGR L + E C
Sbjct 368 PPSAPQELWFEV-QGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCRRC 426
Query 173 -------KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDH-----INFDPVYKV 220
+R S + V + V+A N + +++ D IN ++V
Sbjct 427 RDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEV 486
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P V S+ + ++W P + IL Y ++Y + S
Sbjct 487 PSAVP---VVHQVSRASNSITVSWPQPDQTNGNILDYQLRY---YDQVEDESHSFTLTSE 540
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
++ TV L P Y F++R G G +
Sbjct 541 TNTATVTQLSPGHIYGFQVRARTAAGHGPYG 571
Score = 64.1 bits (154), Expect = 5e-09, Method: Composition-based stats.
Identities = 27/213 (13%), Positives = 54/213 (25%), Gaps = 31/213 (15%)
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
+ P P + QG + L W+ G +L + V + + +
Sbjct 360 PPEAPCTGPPSAPQELWFEVQGS-ALMLHWRLPRELGGRGDLL-FNVVCKECEGRQEPAS 417
Query 382 VNA---------------------TKLTVNLTND--RYLATLTVRNLVGK-----SDAAV 413
+++ V Y+ + N V + AA
Sbjct 418 GGGGTCRRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAA 477
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQE 473
+ + + + + N + V W + IL++ +
Sbjct 478 INVSTSHEVPSAVPVVHQVSRASNSITVSW-PQPDQTNGNILDYQLRYYDQVEDESHSFT 536
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ T L+ Y V A G G
Sbjct 537 LTSETNTATVTQLSPGHIYGFQVRARTAAGHGP 569
>sp|Q9XSZ1|GHR_PAPAN Growth hormone receptor OS=Papio anubis OX=9555
GN=GHR PE=2 SV=1
Length=638
Score = 90.7 bits (223), Expect = 2e-17, Method: Composition-based stats.
Identities = 40/210 (19%), Positives = 83/210 (40%), Gaps = 26/210 (12%)
Query 128 KPKNLSCIVNEGKKMRCEW-----DGGRETH-LETNFTLKSEWA-THKFADCKAK-RDTP 179
+PK C E + C W G + ++ +T ++ T ++ +C
Sbjct 50 EPKFTKCRSPERETFSCHWTDAVHHGSKSLGPIQLFYTRRNIQEWTQEWKECPDYVSAGE 109
Query 180 TSCTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLS----VINSE 234
SC + S ++ + + + T D F V+P+PP L+ ++
Sbjct 110 NSCYFNSSFTSVWIPYCIKLTSNGD----TVDGKCFSVDEIVQPDPPIALNWTLLNVSLT 165
Query 235 ELSSILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + +++ W P + ++L+Y +QY+ + + W + P +S V LK
Sbjct 166 GIHADIQVRWEAPPNADIQKGWMVLEYELQYKEVNETKWKMMDPIL----STSVPVYSLK 221
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
EY R+R + + G + ++SE
Sbjct 222 VDKEYEVRVRSKRRNS-GNYGEFSEVLYVT 250
Score = 61.8 bits (148), Expect = 2e-08, Method: Composition-based stats.
Identities = 65/373 (17%), Positives = 119/373 (32%), Gaps = 48/373 (13%)
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
I EW + P + + ++ + Y I +T G S+
Sbjct 91 IQEWTQEWKECPDYVSAGENSCYFNSSFTSVWI----PYCIKLTSNGDTVDGKCFSVDEI 146
Query 514 LKQAPPSKGPTVRTKKVGKN----EAVLEWDQLP-VDVQNG-FIRNYTIFYRTIIGNETA 567
++ PP V + + W+ P D+Q G + Y + Y+ + +
Sbjct 147 VQPDPPIAL-NWTLLNVSLTGIHADIQVRWEAPPNADIQKGWMVLEYELQYKEVNETKWK 205
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAA--YTDEGGKDGPE-FTFTTPKFAQGEIEA---- 620
+ T + SL D Y VR+ + + E T P+ Q E
Sbjct 206 MMDPILSTSVPVYSLKVDKEYEVRVRSKRRNSGNYGEFSEVLYVTLPQMNQFTCEEDFYF 265
Query 621 -IVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPS---------KSHIAQWSPHT 670
++ + T++ +F F+K+ IK I P VP P K +
Sbjct 266 PWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTI 325
Query 671 PPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGG 730
H+ + D + + E ++K + + L ++ + G G
Sbjct 326 LAIHDSYKPEFHSDDSWVEFIELDIDEPDEKNEGSDTDRLLSSDHQKSHSNLGVKD--GD 383
Query 731 SSCMSSSRPSISSSDENESS--QNTSSTVQYSTVVH--------------SGYRHQVPSV 774
S S P I +D N ++ + TS Q + S Y P+
Sbjct 384 SGRTSCYEPDILETDFNANNIHEGTSEVAQPQRLKGEADLLCLDQKNQNKSPYHDACPAA 443
Query 775 QV--FSRSESTQP 785
Q ++E +P
Sbjct 444 QQSSVIQAEKNKP 456
Score = 40.6 bits (93), Expect = 0.082, Method: Composition-based stats.
Identities = 28/203 (14%), Positives = 57/203 (28%), Gaps = 23/203 (11%)
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL--PPFEANGKILDYEVT- 369
WS ++ + SK P F + T W ++ G I +
Sbjct 34 WSLQSVNPGLKTNSSKEPKF----TKCRSPERETFSCHWTDAVHHGSKSLGPIQLFYTRR 89
Query 370 -LTRWKSHLQNYTVNAT----KLTVNLTNDRYLATLTVR-NLVGKSDAAVLTIPACDFQA 423
+ W + + N + ++ G + Q
Sbjct 90 NIQEWTQEWKECPDYVSAGENSCYFNSSFTSVWIPYCIKLTSNGDTVDGKCFSVDEIVQP 149
Query 424 THPV------MDLKAFPKDNMLWVEWTTPRESVKKY---ILEWCVLSDKAPCITDWQQED 474
P+ +++ + V W P + + +LE+ + K T W+ D
Sbjct 150 DPPIALNWTLLNVSLTGIHADIQVRWEAPPNADIQKGWMVLEYELQY-KEVNETKWKMMD 208
Query 475 GTVHRTYLRGNLAESKCYLITVT 497
+ + +L K Y + V
Sbjct 209 PILSTSVPVYSLKVDKEYEVRVR 231
>sp|O73875|EPB4A_DANRE Ephrin type-B receptor 4a OS=Danio rerio
OX=7955 GN=ephb4a PE=1 SV=3
Length=987
Score = 91.1 bits (224), Expect = 3e-17, Method: Composition-based stats.
Identities = 35/189 (19%), Positives = 60/189 (32%), Gaps = 15/189 (8%)
Query 138 EGKKMRCEWD-----GGRETHLETNFTLKSEWATHKFADCK---AKRDTPTSCTVDYSTV 189
+ EW GGR + C R + T ++
Sbjct 340 NDTSLTLEWSEPLDSGGRSDLSYSVECRMCSTPGSPCTLCSDGVNYRPSQTGIQGRRVSI 399
Query 190 Y----FVNIEVWVEAENALGKVTSDHINFDPVYKVK-PNPPHNLS-VINSEELSSILKLT 243
+ V A N + + + + PN P +S + S S L L
Sbjct 400 WGLRPHTTYSFTVMALNGVSAQSQQGPAGETINITTSPNVPVLVSGLRKSTATESSLTLY 459
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
W P+ IL+Y I+Y K+ + + S + + DL+ T+Y ++R
Sbjct 460 WNTPTQSHYRILQYQIRYCEKERGS-EENSCHYMESNNNEVVLSDLRRATQYEVQVRART 518
Query 304 EDGKGYWSD 312
G G +
Sbjct 519 FAGYGSFGK 527
Score = 89.5 bits (220), Expect = 7e-17, Method: Composition-based stats.
Identities = 48/241 (20%), Positives = 85/241 (35%), Gaps = 27/241 (11%)
Query 435 KDNMLWVEWTTPRESVKKYILEWCV-----LSDKAPCITDWQQEDGTVHRTYLRGN---- 485
D L +EW+ P +S + L + V + +PC + +T ++G
Sbjct 340 NDTSLTLEWSEPLDSGGRSDLSYSVECRMCSTPGSPCTLCSDGVNYRPSQTGIQGRRVSI 399
Query 486 --LAESKCYLITVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
L Y TV + S E+I P +R ++ L
Sbjct 400 WGLRPHTTYSFTVMALNGVSAQSQQGPAGETINITTSPNVPVLVSGLRKSTATESSLTLY 459
Query 539 WDQLPVDVQNGFIRNYTIFY--RTIIGNETAVNV-DSSHTEYTLSSLTSDTLYMVRMAAY 595
W+ I Y I Y + E + + +S++ E LS L T Y V++ A
Sbjct 460 WNTPTQSHYR--ILQYQIRYCEKERGSEENSCHYMESNNNEVVLSDLRRATQYEVQVRAR 517
Query 596 TDEG-GKDGPEFTFTTP-----KFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKK 649
T G G G F T + + I++ + + L+ + ++C K++ K
Sbjct 518 TFAGYGSFGKAILFRTLPDEDDSSSPLLVTGILIAMGMLLLIIVIGAAIYCIRKQNNYKD 577
Query 650 H 650
Sbjct 578 P 578
>sp|O15197|EPHB6_HUMAN Ephrin type-B receptor 6 OS=Homo sapiens
OX=9606 GN=EPHB6 PE=1 SV=4
Length=1021
Score = 91.1 bits (224), Expect = 3e-17, Method: Composition-based stats.
Identities = 41/225 (18%), Positives = 69/225 (31%), Gaps = 27/225 (12%)
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKY-----ILEWCVLSDKAP----------C 466
+L + + L + W PRE + ++ + P C
Sbjct 368 GPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRC 427
Query 467 ITDWQQED---GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYLKQAP 518
+ + G L G L Y++ V V SP+ I
Sbjct 428 RDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEV 487
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEY 577
PS P V N + W Q D NG I +Y + +Y + + S
Sbjct 488 PSAVPVVHQVSRASNSITVSWPQ--PDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTA 545
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAI 621
T++ L+ +Y ++ A T G G + F T + +
Sbjct 546 TVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLP 590
Score = 90.3 bits (222), Expect = 5e-17, Method: Composition-based stats.
Identities = 42/211 (20%), Positives = 69/211 (33%), Gaps = 31/211 (15%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATH-------KFADC 172
PP P+ L V +G + W GGR L + E C
Sbjct 369 PPSAPQELWFEV-QGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRC 427
Query 173 -------KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDH-----INFDPVYKV 220
+R S + V + V+A N + +++ D IN ++V
Sbjct 428 RDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEV 487
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P V S+ + ++W P + IL Y ++Y + S
Sbjct 488 PSAVP---VVHQVSRASNSITVSWPQPDQTNGNILDYQLRY---YDQAEDESHSFTLTSE 541
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
++ TV L P Y F++R G G +
Sbjct 542 TNTATVTQLSPGHIYGFQVRARTAAGHGPYG 572
Score = 64.5 bits (155), Expect = 4e-09, Method: Composition-based stats.
Identities = 27/213 (13%), Positives = 54/213 (25%), Gaps = 31/213 (15%)
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
+ P P + QG + L W+ G +L + V + + +
Sbjct 361 PPEAPCTGPPSAPQELWFEVQGS-ALMLHWRLPRELGGRGDLL-FNVVCKECEGRQEPAS 418
Query 382 VNA---------------------TKLTVNLTND--RYLATLTVRNLVGK-----SDAAV 413
+++ V Y+ + N V + AA
Sbjct 419 GGGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAA 478
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQE 473
+ + + + + N + V W + IL++ +
Sbjct 479 INVSTSHEVPSAVPVVHQVSRASNSITVSW-PQPDQTNGNILDYQLRYYDQAEDESHSFT 537
Query 474 DGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ T L+ Y V A G G
Sbjct 538 LTSETNTATVTQLSPGHIYGFQVRARTAAGHGP 570
>sp|P16871|IL7RA_HUMAN Interleukin-7 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL7R PE=1 SV=3
Length=459
Score = 88.4 bits (217), Expect = 6e-17, Method: Composition-based stats.
Identities = 40/186 (22%), Positives = 78/186 (42%), Gaps = 12/186 (6%)
Query 141 KMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
+ C ++ F + K + + ++ T + + NI V V
Sbjct 54 SLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKV-- 111
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYNI 259
G+ + D VKP P +LSV+ E + ++ ++ K V +L +++
Sbjct 112 ----GEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDV 167
Query 260 QYR-TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED-GKGYWSDWSEEA 317
YR KD + W+ + + +ST+ + + L+P Y ++R + + KG+WS+WS
Sbjct 168 AYRQEKDENKWTHV---NLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSY 224
Query 318 SGITYE 323
T E
Sbjct 225 YFRTPE 230
Score = 56.0 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 45/220 (20%), Positives = 96/220 (44%), Gaps = 32/220 (15%)
Query 556 IFYRTIIGNETAVNVDSSHTEYTL--SSLTSDTLYMVRMAA---YTDEG--GKDGPEFTF 608
+ YR +V+ S T+ TL L +Y +++ + + +G + P + F
Sbjct 167 VAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYF 226
Query 609 TTPKF--AQGEIEAIVVPVC-LAFLLTTLLGVLFCFNKRDLIKKHIWPNVPD-------- 657
TP+ + GE++ I++ + L+F LL +L C + IK +WP++PD
Sbjct 227 RTPEINNSSGEMDPILLTISILSFFSVALLVILACVLWKKRIKPIVWPSLPDHKKTLEHL 286
Query 658 ---PSKSHIAQWSPHTPPRHNFNSKDQMYS----DGNFTDVSVVEIEANDKKPFPEDLKS 710
P K+ ++P + + D + + +G D ++E ++K+ D++S
Sbjct 287 CKKPRKNLNVSFNPESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEESEKQRLGGDVQS 346
Query 711 LDLFKKEKINT------EGHSSGIGGSSCMSSSRPSISSS 744
+ ++ + T + + + G+ + P +SSS
Sbjct 347 PNCPSEDVVITPESFGRDSSLTCLAGN-VSACDAPILSSS 385
>sp|B4F785|EGFLA_RAT Pikachurin OS=Rattus norvegicus OX=10116
GN=Egflam PE=2 SV=1
Length=1005
Score = 89.1 bits (219), Expect = 9e-17, Method: Composition-based stats.
Identities = 37/216 (17%), Positives = 64/216 (30%), Gaps = 17/216 (8%)
Query 411 AAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTTPRES---VKKYILEWCVLSDKAPC 466
A L P +D+K + ++W TP+ S + Y + + L
Sbjct 22 AVSLRTALRKSGKVGPPLDIKLGALNCTAFSIQWKTPKRSGSSIVGYTVFYSELGSDKSL 81
Query 467 ITDWQQEDGTVHRTYLR---GNLAESKCYLITVTPVYADGPGS---PESIKAYLKQA--P 518
G+L Y +++ G G P + + + P
Sbjct 82 REQSHNVPVGQDTLITEEVIGDLKPGTEYRVSIAAYSQTGKGRLSFPRHVTTLSQDSCLP 141
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTI-IGNETAVNVDSSHTE 576
P V +E L W + + I++Y++ F R + T +
Sbjct 142 PEAPHQPHVLVVSDSEVALSWRPG-ENEGSAPIQSYSVEFIRPDFDKSWTIIQERLQMDS 200
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGK--DGPEFTFTT 610
+ L DT Y + A G P T T
Sbjct 201 MVIKGLDPDTNYQFAVRAMNAYGFSLRSQPSNTIRT 236
Score = 79.1 bits (193), Expect = 1e-13, Method: Composition-based stats.
Identities = 47/308 (15%), Positives = 96/308 (31%), Gaps = 26/308 (8%)
Query 127 EKPKNLSCIVNEGKKMRCEWD-GGRETHLETNFTLKSEWAT------HKFADCKAKRDTP 179
P ++ +W R +T+ + + +DT
Sbjct 36 GPPLDIKLGALNCTAFSIQWKTPKRSGSSIVGYTVFYSELGSDKSLREQSHNVPVGQDTL 95
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYK---VKPNPPHNLSVINSEE 235
+ V V + A + GK S + + + + P PH V+ +
Sbjct 96 ITEEVIGDLKPGTEYRVSIAAYSQTGKGRLSFPRHVTTLSQDSCLPPEAPHQPHVLVVSD 155
Query 236 LSSILKLTWTNPSIKSV-IILKYNIQY-RTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
S + L+W + I Y++++ R +W+ I S ++ L P T
Sbjct 156 --SEVALSWRPGENEGSAPIQSYSVEFIRPDFDKSWTIIQERL---QMDSMVIKGLDPDT 210
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDR------PSKAPSFWYKIDPSHTQGYRTV 347
Y F +R M G S S + + P D ++ +
Sbjct 211 NYQFAVRAMNAYGFSLRSQPSNTIRTLGPGEAGSGRYGPGYITDTGVSEDDDASEDELDL 270
Query 348 QLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG 407
+ ++ + P A + + + S+ + + A + +L T G
Sbjct 271 DVSFEEVKPLPA--TKVGNKKSKKTSVSNSEMDSRLAQPTSASLPETTVAVPPTPAQRKG 328
Query 408 KSDAAVLT 415
K+ AV++
Sbjct 329 KNSVAVMS 336
Score = 59.5 bits (142), Expect = 2e-07, Method: Composition-based stats.
Identities = 27/192 (14%), Positives = 49/192 (26%), Gaps = 20/192 (10%)
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKS------HLQNYTV-NATKLTVNL-----TNDRY 396
+ WKT P + I+ Y V + S N V T +T + Y
Sbjct 53 IQWKT--PKRSGSSIVGYTVFYSELGSDKSLREQSHNVPVGQDTLITEEVIGDLKPGTEY 110
Query 397 LATLTVRNLVGKSDAAVLTIPA-----CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK 451
++ + GK + P D+ + + W
Sbjct 111 RVSIAAYSQTGKGRLSFPRHVTTLSQDSCLPPEAPHQPHVLVVSDSEVALSWRPGENEGS 170
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVH-RTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
I + V + W + + + L Y V + A G
Sbjct 171 APIQSYSVEFIRPDFDKSWTIIQERLQMDSMVIKGLDPDTNYQFAVRAMNAYGFSLRSQP 230
Query 511 KAYLKQAPPSKG 522
++ P +
Sbjct 231 SNTIRTLGPGEA 242
Score = 52.2 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 23/106 (22%), Positives = 36/106 (34%), Gaps = 10/106 (9%)
Query 504 PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
PG+ A K ++ + ++W I YT+FY +
Sbjct 20 PGAVSLRTALRKSGKVGPPLDIKLGALNCTAFSIQWKTPKRS--GSSIVGYTVFYSELGS 77
Query 564 N----ETAVNVDSSH----TEYTLSSLTSDTLYMVRMAAYTDEGGK 601
+ E + NV TE + L T Y V +AAY+ G
Sbjct 78 DKSLREQSHNVPVGQDTLITEEVIGDLKPGTEYRVSIAAYSQTGKG 123
>sp|O08644|EPHB6_MOUSE Ephrin type-B receptor 6 OS=Mus musculus
OX=10090 GN=Ephb6 PE=2 SV=4
Length=1014
Score = 89.1 bits (219), Expect = 9e-17, Method: Composition-based stats.
Identities = 39/223 (17%), Positives = 69/223 (31%), Gaps = 25/223 (11%)
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL-----SDKAPCITDW------ 470
+L + + L + W P+E + L + V+ P
Sbjct 363 GPPSAPRELWFEVQGSALMLHWRLPQELGGRGDLLFNVVCKECGGHGEPSSGGMCRRCRD 422
Query 471 -----QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPS 520
++ G L G L Y++ V V SP+ I PS
Sbjct 423 EVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPS 482
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTL 579
P + N + W Q + NG I +Y + +Y + + S T+
Sbjct 483 AVPVMHQVSRAANSITVSWPQ--PEQTNGNILDYQLRYYDQAEDESHSFTMTSETNTATV 540
Query 580 SSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAI 621
+ L+ +Y ++ A T G G + F T + +
Sbjct 541 TRLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLP 583
Score = 84.5 bits (207), Expect = 3e-15, Method: Composition-based stats.
Identities = 39/209 (19%), Positives = 68/209 (33%), Gaps = 29/209 (14%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKSEWATHK-----FADC-- 172
PP P+ L V +G + W GGR L + C
Sbjct 364 PPSAPRELWFEV-QGSALMLHWRLPQELGGRGDLLFNVVCKECGGHGEPSSGGMCRRCRD 422
Query 173 -----KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDH-----INFDPVYKVKP 222
+R S + V + V+A N + +++ D IN ++V
Sbjct 423 EVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPS 482
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P + ++ + ++W P + IL Y ++Y + S +
Sbjct 483 AVP---VMHQVSRAANSITVSWPQPEQTNGNILDYQLRYYDQAEDESHSFTM---TSETN 536
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+ TV L P Y F++R G G +
Sbjct 537 TATVTRLSPGHIYGFQVRARTAAGHGPYG 565
Score = 66.8 bits (161), Expect = 7e-10, Method: Composition-based stats.
Identities = 29/211 (14%), Positives = 55/211 (26%), Gaps = 29/211 (14%)
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
+ P P + QG + L W+ G +L + V H + +
Sbjct 356 PPEAPCTGPPSAPRELWFEVQGS-ALMLHWRLPQELGGRGDLL-FNVVCKECGGHGEPSS 413
Query 382 -------------------VNATKLTVNLTND--RYLATLTVRNLVGK-----SDAAVLT 415
+ +++ V Y+ + N V + AA +
Sbjct 414 GGMCRRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAIN 473
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
+ + + + N + V W E IL++ +
Sbjct 474 VSTSHEVPSAVPVMHQVSRAANSITVSW-PQPEQTNGNILDYQLRYYDQAEDESHSFTMT 532
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ T L+ Y V A G G
Sbjct 533 SETNTATVTRLSPGHIYGFQVRARTAAGHGP 563
Score = 57.9 bits (138), Expect = 4e-07, Method: Composition-based stats.
Identities = 44/238 (18%), Positives = 73/238 (31%), Gaps = 35/238 (15%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII-LKYNIQYRTKDA------- 266
DP PP + E S L L W P L +N+ +
Sbjct 355 DPPEAPCTGPPSAPRELWFEVQGSALMLHWRLPQELGGRGDLLFNVVCKECGGHGEPSSG 414
Query 267 ------STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
P T S V L+ Y+ ++ + G S +A+ I
Sbjct 415 GMCRRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVN--GVSELSPDPPQAAAI 472
Query 321 ---TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT---RWK 374
T + PS P + ++ ++ + W P + NG ILDY++ +
Sbjct 473 NVSTSHEVPSAVP-----VMHQVSRAANSITVSW--PQPEQTNGNILDYQLRYYDQAEDE 525
Query 375 SHLQNYTVNATKLTVNLTNDRYLA--TLTVRNLVGKSD----AAVLTIPACDFQATHP 426
SH T TV + ++ + R G T+P + + P
Sbjct 526 SHSFTMTSETNTATVTRLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLP 583
>sp|P21709|EPHA1_HUMAN Ephrin type-A receptor 1 OS=Homo sapiens
OX=9606 GN=EPHA1 PE=1 SV=4
Length=976
Score = 89.1 bits (219), Expect = 1e-16, Method: Composition-based stats.
Identities = 35/206 (17%), Positives = 66/206 (32%), Gaps = 26/206 (13%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHKFADCKAKRDTPTSC 182
PP P+NLS G ++ W+ +T + ++++ D +
Sbjct 332 PPSAPRNLS-FSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDGGPCQPCGVGV 390
Query 183 TVDYSTVY-------------FVNIEVWVEAENALGKVTSDHINFDPVYK--VKPNPPHN 227
+ N VEA+N + + S V
Sbjct 391 HFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSISMGHAESLSG 450
Query 228 LSVINSEELSSILKLTWT-NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 286
LS+ ++ L+LTW + L Y + +D + + +
Sbjct 451 LSLRLVKKEPRQLELTWAGSRPRSPGANLTYELHVLNQDEERYQMVLE-------PRVLL 503
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSD 312
+L+P T Y+ R+R + G G +S
Sbjct 504 TELQPDTTYIVRVRMLTPLGPGPFSP 529
Score = 71.8 bits (174), Expect = 2e-11, Method: Composition-based stats.
Identities = 36/216 (17%), Positives = 59/216 (27%), Gaps = 25/216 (12%)
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDK-----------APCITDW 470
+L L + W P ++ + + + V + PC
Sbjct 331 GPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDGGPCQPCGVGV 390
Query 471 QQEDGT---VHRTYLRGNLAESKCYLITVTPVYA-DGPGSP----ESIKAYLKQAPPSKG 522
G L Y V G GS S+ + A G
Sbjct 391 HFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSISMGHAESLSG 450
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
++R K + L W + Y + + + L+ L
Sbjct 451 LSLRLVKKEPRQLELTWAGSRPRSPGANLT-YELHVLNQDEERYQMVL---EPRVLLTEL 506
Query 583 TSDTLYMVRMAAYTDEGGKD-GPEFTFTT-PKFAQG 616
DT Y+VR+ T G P+ F T P ++G
Sbjct 507 QPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVSRG 542
Score = 57.6 bits (137), Expect = 6e-07, Method: Composition-based stats.
Identities = 37/212 (17%), Positives = 62/212 (29%), Gaps = 23/212 (11%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWS--- 270
P+ P NLS S + L L W P+ ++Y+++ +
Sbjct 326 QVACTGPPSAPRNLSFSASG---TQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDGGP 382
Query 271 --------QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE-DGKGYWSDWSEEASGIT 321
P T + V L+P+ Y F + G G S S
Sbjct 383 CQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSISM 442
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV-TLTRWKSHLQNY 380
S + R ++L W P G L YE+ L + + Q
Sbjct 443 GHAESLSGLSLRLV-----KKEPRQLELTWAGSRPRSP-GANLTYELHVLNQDEERYQMV 496
Query 381 TVNATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
LT + Y+ + + +G +
Sbjct 497 LEPRVLLTELQPDTTYIVRVRMLTPLGPGPFS 528
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 37/243 (15%), Positives = 68/243 (28%), Gaps = 39/243 (16%)
Query 314 SEEASGITYED----RPSKAPSFWYKIDPSH------TQGYRTVQLVWKTLPPFEANGKI 363
SE A+ T E P + P PS + + L W+ +
Sbjct 305 SEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDV 364
Query 364 LDYEVTLTRWKSHLQNYTV-----------------NATKLTVNLTND--RYLATLTVRN 404
Y V ++ + Q+ + VN Y + +N
Sbjct 365 R-YSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQN 423
Query 405 LV---GKS--DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
V G S + ++I ++ + + L + W R L + +
Sbjct 424 GVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGANLTYEL 483
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
D ++ + L L Y++ V + GPG + P
Sbjct 484 HVLNQ----DEERYQMVLEPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPV 539
Query 520 SKG 522
S+G
Sbjct 540 SRG 542
>sp|Q9JI97|GHR_CAVPO Growth hormone receptor OS=Cavia porcellus
OX=10141 GN=GHR PE=2 SV=1
Length=628
Score = 88.4 bits (217), Expect = 1e-16, Method: Composition-based stats.
Identities = 42/203 (21%), Positives = 74/203 (36%), Gaps = 27/203 (13%)
Query 129 PKNLSCIVNEGKKMRCEW-----DGGRETH-LETNFTLK-SEWATHKFADCKAK-RDTPT 180
PK C E + C W G + T ++ +T + S+ ++ +C
Sbjct 51 PKFTKCRSPELETFSCHWTDEGHHGLKSTGFIQMFYTKRNSQEQNQEWKECPDYVSAGEN 110
Query 181 SCTVDYSTVYFVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
SC + S V + + D F V+P+PP L+ ++
Sbjct 111 SCYFNSSYTSIWKPYCVKLTSNGG----KVDEKCFYVEEIVQPDPPTGLNWTLMNTSATA 166
Query 240 L----KLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ ++ W P V I+L Y +Q + + + W + P T +S + L+
Sbjct 167 IYGDIQVRWKPPRSADVKKGWIMLDYELQIKQTNETQWKMMDPV----TSTSVPLYSLRL 222
Query 292 FTEYVFRIRCM--KEDGKGYWSD 312
EY RIR D G +S+
Sbjct 223 DKEYEVRIRSRLQNSDKYGEFSE 245
Score = 56.8 bits (135), Expect = 7e-07, Method: Composition-based stats.
Identities = 77/381 (20%), Positives = 126/381 (33%), Gaps = 71/381 (19%)
Query 512 AYLKQAPPSKGPTVRTKKVGKNE-------AVLEWDQLP-VDVQNGFIR-NYTIFYRTII 562
Y+++ PT + + W DV+ G+I +Y + +
Sbjct 141 FYVEEIVQPDPPTGLNWTLMNTSATAIYGDIQVRWKPPRSADVKKGWIMLDYELQIKQTN 200
Query 563 GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY--TDEGGKDGPE-FTFTTPKFAQGE-I 618
+ + + T L SL D Y VR+ + + + E T P+ +
Sbjct 201 ETQWKMMDPVTSTSVPLYSLRLDKEYEVRIRSRLQNSDKYGEFSEILYITLPQSSPFTCE 260
Query 619 EAIVVPVCL----AFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRH 674
E P L T++ ++ F+K+ IK I P VP P I P
Sbjct 261 EEFQFPWFLIMIFGIFGLTVMLLVVMFSKQQRIKMLILPPVPVP---KIKGVDPDLLKEG 317
Query 675 NF-----------NSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEG 723
NSK Q Y+D ++ + ++I+ +D+K D L +K +
Sbjct 318 KLEEVNTILAIHDNSKPQFYNDDSWVEFIELDIDDSDEKIEGSDTDRLLSSDHQK-SLNI 376
Query 724 HSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVH--------------SGYRH 769
+ G S S P I +D N ++ TS VQ + S
Sbjct 377 LGAKDGDSGRTSCYEPDILEADFN-ANDGTSEDVQPDKLKEEADLLCLDEKNQNNSPC-D 434
Query 770 QVPSVQVFS----RSESTQPLL------DSEERPEDL-------------QLVDHVDGGD 806
P Q E QPLL +++ P + Q+ D G
Sbjct 435 APPDPQQALVIPPEEEKPQPLLIGKTESTNQDAPNQISNPISLANMDFYAQVSDITPAGS 494
Query 807 GILPRQQYFKQNCSQHESSPD 827
+L Q K SQ E+ P+
Sbjct 495 VVLSPGQKNKAGLSQCEAHPE 515
Score = 38.7 bits (88), Expect = 0.30, Method: Composition-based stats.
Identities = 31/161 (19%), Positives = 50/161 (31%), Gaps = 12/161 (7%)
Query 371 TRWKSHLQNYTVNATKLTVNLTNDR--YLATLTVRNLVGKSDA---AVLTIPACDFQATH 425
WK + N + + + + GK D V I D
Sbjct 96 QEWKECPDYVSAGENSCYFNSSYTSIWKPYCVKLTSNGGKVDEKCFYVEEIVQPDPPTGL 155
Query 426 --PVMDLKAFPKDNMLWVEWTTPRES--VKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
+M+ A + V W PR + K +I+ L K T W+ D +
Sbjct 156 NWTLMNTSATAIYGDIQVRWKPPRSADVKKGWIMLDYELQIKQTNETQWKMMDPVTSTSV 215
Query 482 LRGNLAESKCYLITVTPV--YADGPGS-PESIKAYLKQAPP 519
+L K Y + + +D G E + L Q+ P
Sbjct 216 PLYSLRLDKEYEVRIRSRLQNSDKYGEFSEILYITLPQSSP 256
>sp|Q95LF0|I13R2_CANLF Interleukin-13 receptor subunit alpha-2
OS=Canis lupus familiaris OX=9615 GN=IL13RA2 PE=2 SV=1
Length=386
Score = 86.8 bits (213), Expect = 1e-16, Method: Composition-based stats.
Identities = 49/203 (24%), Positives = 74/203 (36%), Gaps = 31/203 (15%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWAT----HKFADCKAKRDTPTSCTVD 185
+++ C+ + + C W G H +TN+ L + + D C
Sbjct 140 QDMDCVYYNWQYLVCSWKPGMGVHFDTNYQLFYWYEGLDHSAECTDYIKVNGKNMGCRFP 199
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHIN-----FDPVYKVKPNPP--HNLSVINSEELSS 238
Y + ++ G S I F VKP PP +L+V NSEE
Sbjct 200 YLESSDYK-DFYICVN---GSSESQPIRPSYFIFQLQNIVKPMPPDYLSLTVKNSEE--- 252
Query 239 ILKLTWTNPSIK-SVIILKYNIQYRTKDASTWSQIPPED-TASTRSSFTVQDLKPFTEYV 296
+ L W P Y I++ T+D +TW E+ TR+S Q L
Sbjct 253 -INLKWNMPKGPIPAKCFIYEIEF-TEDGTTWVTTTVENEIQITRTSNESQKL------C 304
Query 297 FRIRCMKED---GKGYWSDWSEE 316
F +R G WS+WS+E
Sbjct 305 FLVRSKVNIYCSDDGIWSEWSDE 327
Score = 64.9 bits (156), Expect = 1e-09, Method: Composition-based stats.
Identities = 41/285 (14%), Positives = 83/285 (29%), Gaps = 41/285 (14%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI---ILKYNIQYRTKDASTWSQIPPED 276
+K NPP + +++ L L W P ++Y ++YR D+ W I ++
Sbjct 29 IKVNPPQDFEIVD-PGYLGYLSLQWQPPLFPDNFKECTIEYELKYRNIDSENWKTIITKN 87
Query 277 T-------ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
+ + L P +C G S W+E TY P
Sbjct 88 LHYKDGFDLNKGIEAKINTLLPA-------QCTN--GSEVRSSWAE----TTYWTSPQGN 134
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--------RWKSHLQNYT 381
+ ++ + WK + +Y++ +++
Sbjct 135 RETKIQDMDCVYYNWQYLVCSWKPGMGVHFD---TNYQLFYWYEGLDHSAECTDYIKVNG 191
Query 382 VNATKLTVNLTNDRYLATLTVRNLVGKS----DAAVLTIPACDFQATHPVMDLKAFPKDN 437
N L + Y N +S + + + P
Sbjct 192 KNMGCRFPYLESSDYKDFYICVNGSSESQPIRPSYFIFQLQNIVKPMPPDYLSLTVKNSE 251
Query 438 MLWVEWTTPRESVKK--YILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ ++W P+ + +I E D +T + + + RT
Sbjct 252 EINLKWNMPKGPIPAKCFIYEIEFTEDGTTWVTTTVENEIQITRT 296
>sp|P13595|NCAM1_MOUSE Neural cell adhesion molecule 1 OS=Mus
musculus OX=10090 GN=Ncam1 PE=1 SV=3
Length=1115
Score = 89.1 bits (219), Expect = 1e-16, Method: Composition-based stats.
Identities = 71/421 (17%), Positives = 124/421 (29%), Gaps = 54/421 (13%)
Query 44 FTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIIN----RTASSVTFTDIASLNI 99
T C + I W+T+ I E+ T+ R+ + V+ + S+
Sbjct 326 VTLTC-------EASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQY 378
Query 100 QLTCNILT-----FGQLEQNVYGITIISGLPPE--KPKNLSCIVNEGKKMRCEWDGGRET 152
+ GQ Q++Y + P+ P + + C E
Sbjct 379 TDAGEYICTASNTIGQDSQSMY---LEFQYAPKLQGPVAVYTWEGNQVNITC------EV 429
Query 153 HLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHI 212
+ T+ Y+T +EV ++EN G +
Sbjct 430 FAYPSATISWFRDGQLLPSSNYSN------IKIYNTPSASYLEVTPDSENDFGNYNCTAV 483
Query 213 NFDPVYK-----VKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDA 266
N V+ + P + S+ E SS ++ + P ILKY ++++
Sbjct 484 NRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLGE 543
Query 267 STWSQIPPEDTASTRSS-FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
+W + + T+ LKP T Y R+ + G G S +E T R
Sbjct 544 ESWHFKWYDAKEANMEGIVTIMGLKPETRYSVRLAALNGKGLGEISAATE---FKTQPVR 600
Query 326 PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT----RWKSHLQNYT 381
AP ++ + + I Y V WK ++ +
Sbjct 601 EPSAPKLEGQMGEDGNSIKVNLI------KQDDGGSPIRHYLVKYRALASEWKPEIRLPS 654
Query 382 VNATKLTVNLT-NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW 440
+ + +L N Y + N GKS AA P
Sbjct 655 GSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTAGLSTGAI 714
Query 441 V 441
V
Sbjct 715 V 715
Score = 86.4 bits (212), Expect = 8e-16, Method: Composition-based stats.
Identities = 41/281 (15%), Positives = 89/281 (32%), Gaps = 22/281 (8%)
Query 386 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT 445
++T + ND T N +G+ + + A + P + V++
Sbjct 466 EVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDR---VEPYSSTAQVQFDE 522
Query 446 PRE----SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
P + KY EW L +++ + ++ + L Y + + +
Sbjct 523 PEATGGVPILKYKAEWKSLGEESWHFKWYDAKEANMEGIVTIMGLKPETRYSVRLAALNG 582
Query 502 DGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G G + + + P + + ++ + + D IR+Y + YR
Sbjct 583 KGLGEISAATEFKTQPVREPSAPKLEGQMGEDGN-SIKVNLIKQDDGGSPIRHYLVKYRA 641
Query 561 IIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT--------- 610
+ + + S L SL + Y V + A +G F F T
Sbjct 642 LASEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPA 701
Query 611 ---PKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIK 648
P + + + + LL ++ + F + +
Sbjct 702 NGSPTAGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLL 742
>sp|Q14627|I13R2_HUMAN Interleukin-13 receptor subunit alpha-2
OS=Homo sapiens OX=9606 GN=IL13RA2 PE=1 SV=1
Length=380
Score = 86.4 bits (212), Expect = 1e-16, Method: Composition-based stats.
Identities = 45/203 (22%), Positives = 74/203 (36%), Gaps = 21/203 (10%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWAT----HKFADCKAKRDT 178
G+P K +++ C+ + + C W G L+TN+ L + + D
Sbjct 134 GIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDHALQCVDYIKADGQ 193
Query 179 PTSCTVDYSTV---YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
C Y I V +EN + S + F VKP PP L+ + E
Sbjct 194 NIGCRFPYLEASDYKDFYICVNGSSENKP--IRSSYFTFQLQNIVKPLPPVYLT--FTRE 249
Query 236 LSSILKLTWTNPSIK-SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
S +KL W+ P Y I+ R D + + +T + +++ + L
Sbjct 250 SSCEIKLKWSIPLGPIPARCFDYEIEIREDDTTLVTATVENETYTLKTTNETRQL----- 304
Query 295 YVFRIRCMKED---GKGYWSDWS 314
F +R G WS+WS
Sbjct 305 -CFVVRSKVNIYCSDDGIWSEWS 326
Score = 61.4 bits (147), Expect = 2e-08, Method: Composition-based stats.
Identities = 39/298 (13%), Positives = 86/298 (29%), Gaps = 40/298 (13%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI---ILKYNIQYRTKDASTWSQIPPED 276
+K NPP + +++ L L W P ++Y ++YR + TW I ++
Sbjct 30 IKVNPPQDFEIVD-PGYLGYLYLQWQPPLSLDHFKECTVEYELKYRNIGSETWKTIITKN 88
Query 277 T-------ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
+ + L P+ +C G S W+E I+ + P
Sbjct 89 LHYKDGFDLNKGIEAKIHTLLPW-------QCTN--GSEVQSSWAETTYWISPQGIPETK 139
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--------RWKSHLQNYT 381
+ + + WK + +Y + + +++
Sbjct 140 VQDMDCVYYNWQ----YLLCSWKPGIGVLLD---TNYNLFYWYEGLDHALQCVDYIKADG 192
Query 382 VNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ---ATHPVMDLKAFPKDNM 438
N L Y N ++ + Q P + L + +
Sbjct 193 QNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSC 252
Query 439 -LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLIT 495
+ ++W+ P + ++ + + T T N C+++
Sbjct 253 EIKLKWSIPLGPIPARCFDYEIEIRED-DTTLVTATVENETYTLKTTNETRQLCFVVR 309
>sp|Q38IC7|IL7RA_MACFA Interleukin-7 receptor subunit alpha OS=Macaca
fascicularis OX=9541 GN=IL7R PE=2 SV=1
Length=459
Score = 87.2 bits (214), Expect = 1e-16, Method: Composition-based stats.
Identities = 41/186 (22%), Positives = 76/186 (41%), Gaps = 12/186 (6%)
Query 141 KMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
+ C ++ F + K + ++ T + + NI V V
Sbjct 54 SLTCAFEDPDVNTTNLEFEICGALVEVKCLSFRKLQEIYFIETKKFLLIGKSNICVKV-- 111
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYNI 259
G + D VKP P +LSVI E + ++ ++ K V +L +++
Sbjct 112 ----GGKSLTCKKIDLTTIVKPEAPFDLSVIYREGANDFVVTFNTSHLQKKYVKVLMHDV 167
Query 260 QYR-TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED-GKGYWSDWSEEA 317
YR KD + W + + +ST+ + ++L+P Y ++R + + KG+WS+WS
Sbjct 168 AYRQEKDENKWMHV---NLSSTKLTLLQRNLQPEAMYEIKVRSIPDHYFKGFWSEWSPSY 224
Query 318 SGITYE 323
T E
Sbjct 225 YFRTPE 230
Score = 56.8 bits (135), Expect = 5e-07, Method: Composition-based stats.
Identities = 29/112 (26%), Positives = 58/112 (52%), Gaps = 10/112 (9%)
Query 556 IFYRTIIGNETAVNVDSSHTEYTL--SSLTSDTLYMVRMAA---YTDEG--GKDGPEFTF 608
+ YR ++V+ S T+ TL +L + +Y +++ + + +G + P + F
Sbjct 167 VAYRQEKDENKWMHVNLSSTKLTLLQRNLQPEAMYEIKVRSIPDHYFKGFWSEWSPSYYF 226
Query 609 TTPKF--AQGEIEAIVVPVCL-AFLLTTLLGVLFCFNKRDLIKKHIWPNVPD 657
TP+ + GE++ I++ + L +F LL +L C + IK +WP++PD
Sbjct 227 RTPEINNSPGEMDPILLTISLLSFFSVALLVILACVLWKKRIKPIVWPSLPD 278
>sp|Q60750|EPHA1_MOUSE Ephrin type-A receptor 1 OS=Mus musculus
OX=10090 GN=Epha1 PE=1 SV=2
Length=977
Score = 88.8 bits (218), Expect = 1e-16, Method: Composition-based stats.
Identities = 37/207 (18%), Positives = 68/207 (33%), Gaps = 28/207 (14%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETH--LETNFTLKSEWA------THKFADC---- 172
PP P+NLS G ++ W+ R+T + ++++ C
Sbjct 333 PPSAPQNLS-FSTSGTQLSLRWEPPRDTGGRHDIRYSVECLQCRGIAQDGGPCQPCGKGV 391
Query 173 ---KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG--KVTSDHINFDPVYKVKPNPPHN 227
A TS + N V+++N + +S +
Sbjct 392 HFSPAASGLTTSTVQVQGLEPYANYTFTVKSQNRVSGLDSSSPSSASLSINMGHAESLSG 451
Query 228 LSVINSEELSSILKLTW--TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
LS+ ++ L+LTW + P L Y + +D +
Sbjct 452 LSLKLVKKEPRQLELTWAGSRPRNPGG-NLSYELHVLNQDEEWHQMVLE-------PRVL 503
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ L+P T Y+ R+R + G G +S
Sbjct 504 LTKLQPDTTYIVRVRTLTPLGPGPFSP 530
Score = 73.7 bits (179), Expect = 6e-12, Method: Composition-based stats.
Identities = 41/226 (18%), Positives = 69/226 (31%), Gaps = 29/226 (13%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV--------LSDKAPCITDWQQE- 473
+L L + W PR++ ++ + + V D PC +
Sbjct 333 PPSAPQNLSFSTSGTQLSLRWEPPRDTGGRHDIRYSVECLQCRGIAQDGGPCQPCGKGVH 392
Query 474 -----DGTVHRTYLRGNLAESKCYLITVTPVYADGP-----GSPESIKAYLKQAPPSKGP 523
G T L Y TV S S+ + A G
Sbjct 393 FSPAASGLTTSTVQVQGLEPYANYTFTVKSQNRVSGLDSSSPSSASLSINMGHAESLSGL 452
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLT 583
+++ K + L W G + +Y + + + L+ L
Sbjct 453 SLKLVKKEPRQLELTWAGSRPRNPGGNL-SYELHVLNQDEEWHQMVL---EPRVLLTKLQ 508
Query 584 SDTLYMVRMAAYTDEGGKD-GPEFTFTT-PKFAQ----GEIEAIVV 623
DT Y+VR+ T G P+ F T P ++ GEI A++
Sbjct 509 PDTTYIVRVRTLTPLGPGPFSPDHEFRTSPPVSRSLTGGEIVAVIF 554
Score = 51.8 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 41/209 (20%), Positives = 65/209 (31%), Gaps = 29/209 (14%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWS--------- 270
P+ P NLS S + L L W P ++Y+++
Sbjct 333 PPSAPQNLSFSTSG---TQLSLRWEPPRDTGGRHDIRYSVECLQCRGIAQDGGPCQPCGK 389
Query 271 --QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE-DGKGYWSDWSEEASGITYEDRPS 327
P + T S+ VQ L+P+ Y F ++ G S S S
Sbjct 390 GVHFSPAASGLTTSTVQVQGLEPYANYTFTVKSQNRVSGLDSSSPSSASLSINMGHAESL 449
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL----TRWKSHLQNYTVN 383
S + R ++L W P G L YE+ + W + V
Sbjct 450 SGLSLKLV-----KKEPRQLELTWAGSRPRNPGGN-LSYELHVLNQDEEWHQMVLEPRVL 503
Query 384 ATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
TKL + T Y+ + +G +
Sbjct 504 LTKLQPDTT---YIVRVRTLTPLGPGPFS 529
>sp|Q973G3|Y939_SULTO Kelch domain-containing protein STK_09390
OS=Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 /
NBRC 100140 / 7) OX=273063 GN=STK_09390 PE=3 SV=1
Length=709
Score = 88.0 bits (216), Expect = 2e-16, Method: Composition-based stats.
Identities = 61/399 (15%), Positives = 123/399 (31%), Gaps = 72/399 (18%)
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL--------GKVTS 209
+ + + + T+ T + + V+ N L G + S
Sbjct 249 YYVSGAYQLGEILYYYNGTWRNTNIQEQIPTQFSTS----VQIGNKLIILGGFGPGNIPS 304
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTW 269
+ + +Y P P + + + + + W + + S + Y W
Sbjct 305 NAMQTVSIYLPPPKP----QIASIASGNETITVKWYD-TNASGYYITY-----------W 348
Query 270 SQIPPEDT--ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
S + T +S+T++ LK Y +I G G SD T P+
Sbjct 349 SNFSQKVTINVGNVTSYTIKHLKDGVTYYIQIVPYNSLGNGTPSD----IISATPSSVPN 404
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG--KILDYEVTLTRWKSHLQNYTVNAT 385
+ L W NG I Y + + ++ N T +
Sbjct 405 PPIIKVKIGNL-------NATLTWYD----TFNGGYPIEGYYLYVNGKGINVGNIT---S 450
Query 386 KLTVNLT-NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
+ NLT + Y L N +G S + ++ A+ + + + K N V W
Sbjct 451 YVLTNLTAGELYTIELIAYNKIGNSSISSVSF----IAASKANLTVTVYKKINGFLVSWN 506
Query 445 TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
+ ++ ++ + K + T +++ Y I++ V G
Sbjct 507 STSKA------KYILTVSKENVVL--LNVSTTNTSYFVK---VPFGVYNISLEAVNIVGI 555
Query 505 GS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQL 542
+ Y++ A P+ + N L W ++
Sbjct 556 TKYAFILIYYIQPASPTVN-----WSITLNTVSLNWSKV 589
Score = 84.1 bits (206), Expect = 3e-15, Method: Composition-based stats.
Identities = 51/257 (20%), Positives = 88/257 (34%), Gaps = 27/257 (11%)
Query 354 LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS--DA 411
+ G+IL Y R +++Q +V + N L + G +
Sbjct 251 VSGAYQLGEILYYYNGTWR-NTNIQEQIPTQFSTSVQIGN-----KLIILGGFGPGNIPS 304
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
+ + P + A + + V+W + YI W S K
Sbjct 305 NAMQTVSIYLPPPKPQIASIASGNET-ITVKW-YDTNASGYYITYWSNFSQK-------V 355
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
+ +Y +L + Y I + P + G G+P I + + P P + K+G
Sbjct 356 TINVGNVTSYTIKHLKDGVTYYIQIVPYNSLGNGTPSDIISATPSSVP--NPPIIKVKIG 413
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
A L W I Y ++ N +NV + T Y L++LT+ LY +
Sbjct 414 NLNATLTW--YDTFNGGYPIEGYYLYV-----NGKGINV-GNITSYVLTNLTAGELYTIE 465
Query 592 MAAYTDEGGKDGPEFTF 608
+ AY G +F
Sbjct 466 LIAYNKIGNSSISSVSF 482
Score = 58.3 bits (139), Expect = 2e-07, Method: Composition-based stats.
Identities = 42/294 (14%), Positives = 86/294 (29%), Gaps = 36/294 (12%)
Query 351 WK---TLPPFEANGKIL---DYEVTLTRWKSHLQNYTVNATKLT--VNLTNDRYLA---- 398
WK P G I+ DY++ + ++ N V NL + +
Sbjct 119 WKVITNSMPIPVYGAIVFSYDYKIYVIGGMNYSGNSLVPPVNYIQVYNLKTNSWQIIGNA 178
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWC 458
L + + + L + Q+ + + +N W+ + +L +
Sbjct 179 PLRLAYSAYYFNGSALFVVGGFTQSATLTSSVFVYYPENNTWISLPSLPGVEAGGVLGYY 238
Query 459 VLSDKAPCITDWQ-------QEDGTVHRTYLRGNLAESKCYLITVTPVYAD--------G 503
+ + + T+ N+ E + + + G
Sbjct 239 NGYMYLVGGLYYVSGAYQLGEILYYYNGTWRNTNIQEQIPTQFSTSVQIGNKLIILGGFG 298
Query 504 PGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII 562
PG+ P + + P P + + G ++W Y I Y +
Sbjct 299 PGNIPSNAMQTVSIYLPPPKPQIASIASGNETITVKWYDTNAS-------GYYITYWSNF 351
Query 563 GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
+ +NV + T YT+ L Y +++ Y G + TP
Sbjct 352 SQKVTINV-GNVTSYTIKHLKDGVTYYIQIVPYNSLGNGTPSDIISATPSSVPN 404
>sp|Q64455|PTPRJ_MOUSE Receptor-type tyrosine-protein phosphatase
eta OS=Mus musculus OX=10090 GN=Ptprj PE=1 SV=2
Length=1238
Score = 88.8 bits (218), Expect = 2e-16, Method: Composition-based stats.
Identities = 63/355 (18%), Positives = 111/355 (31%), Gaps = 45/355 (13%)
Query 273 PPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS----K 328
PP + + + DLKP T+Y I +G E +P K
Sbjct 221 PPSGQDPSLTEILLTDLKPDTQYNATIYSQAANG---------------TEGQPRNKVFK 265
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD--YEVTLTRWKSHLQNYTVNATK 386
S + ++ L WK +G Y++ + +H N TVN T+
Sbjct 266 TNSTQVSDVRAMNISASSMTLTWK----SNYDGSRTSIVYKIHV-AGGTHSVNQTVNKTE 320
Query 387 LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
+ + L +TV +G+++ + + + + W
Sbjct 321 AIILGLSSSTLYNITVHPFLGQTEGTPGFLQVYTSPDQVSDFRVTNV-STRAIGLAWR-- 377
Query 447 RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADG-PG 505
K + + + + T +++Y+ +L Y + P DG G
Sbjct 378 SNDSKSFEIFIKQDGGEK------HRNASTGNQSYMVEDLKPGTSYHFEIIPRGPDGTEG 431
Query 506 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE 565
++ PS +R + E LEW YT +
Sbjct 432 LSSTVNGSTD---PSAVTDIRVVNISTTEMQLEWQNTDDAS------GYTYHLVLESKSG 482
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
+ + +SS T+ SLT TLY V + D+ T T + IE
Sbjct 483 SIIRTNSSQKWITVGSLTPGTLYNVTIFPEVDQIQGISNSITQYTRPSSVSHIEV 537
Score = 86.1 bits (211), Expect = 1e-15, Method: Composition-based stats.
Identities = 71/450 (16%), Positives = 125/450 (28%), Gaps = 105/450 (23%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
PNP ++ + + + LTW + + + I+ + + T +
Sbjct 40 PNPIFDIEAV---VSPTSVLLTWKHNDSGAS---ECRIENKMESNLT-------FPVKNQ 86
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+S + L P T Y F I + + E T P W D T
Sbjct 87 TSCNITGLSPGTSYTFSIISVT----------TNETLNKTITTEP------WPVSDLHVT 130
Query 342 Q-GYRTVQLVWKTLPPFEAN-----GKILDYEVTLTRWKSHLQNY--------------- 380
G +L W + V ++ K N
Sbjct 131 SVGVTQARLTWSNANGTASYRMLIEELTTHSSVNISGLKPGTNNSFAFPESNETQADFAV 190
Query 381 -----TVNATK-LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA----------- 423
N TK + V + + +L + D ++ I D +
Sbjct 191 AEEVPDANGTKRIPVTNLSQLHKNSLVSVDPPSGQDPSLTEILLTDLKPDTQYNATIYSQ 250
Query 424 -----------------THPVMDLKAFPKD-NMLWVEWTTPRESVKKYILEWCVLSDKAP 465
+ V D++A + + + W + + + I+ + +
Sbjct 251 AANGTEGQPRNKVFKTNSTQVSDVRAMNISASSMTLTWKSNYDGSRTSIV-YKIHVAGG- 308
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
T + + G L+ S Y ITV P G+P ++ Y P +
Sbjct 309 --THSVNQTVNKTEAIILG-LSSSTLYNITVHPFLGQTEGTPGFLQVYTS---PDQVSDF 362
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
R V L W FI+ G E N + + Y + L
Sbjct 363 RVTNVSTRAIGLAWRSNDSKSFEIFIKQ--------DGGEKHRNASTGNQSYMVEDLKPG 414
Query 586 TLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ 615
T Y + G DG E +T +
Sbjct 415 TSYHFEIIPR----GPDGTEGLSSTVNGST 440
Score = 68.7 bits (166), Expect = 2e-10, Method: Composition-based stats.
Identities = 73/479 (15%), Positives = 130/479 (27%), Gaps = 57/479 (12%)
Query 140 KKMRCEWDGGRETH-LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
M W + + + TH K + + + V
Sbjct 282 SSMTLTWKSNYDGSRTSIVYKIHVAGGTHSVNQTVNKTE-----AIILGLSSSTLYNITV 336
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
LG+ P+ + V N + + L W + KS +
Sbjct 337 HPF--LGQTEGTPGFLQVY--TSPDQVSDFRVTNV--STRAIGLAWRSNDSKS-----FE 385
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
I + + ++ S+ V+DLKP T Y F I DG
Sbjct 386 IFIKQDGGE-----KHRNASTGNQSYMVEDLKPGTSYHFEIIPRGPDG----------TE 430
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
G++ S PS I +QL W+ Y + L +
Sbjct 431 GLSSTVNGSTDPSAVTDIRVV-NISTTEMQLEWQNTDDASGY----TYHLVLESKSGSII 485
Query 379 NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
+ +TV L +T+ V ++ + V ++
Sbjct 486 RTNSSQKWITVGSLTPGTLYNVTIFPEVD--QIQGISNSITQYTRPSSVSHIEVNTTTTT 543
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
+ W E + VL K ++ + T + L L Y + +
Sbjct 544 AAIRWK--NEDAASASYAYSVLILKTGDGSNVT-SNFTKDPSILIPELIPGVSYTVKILT 600
Query 499 VYADGPGSPES-IKAYLKQAPPSKGPTVRTKKVGKN-EAVLEWDQLPVDVQNGFIRNYTI 556
DG S + + P + + V K VL+W G + +
Sbjct 601 QVGDGTTSLVPGWNLFCTE--PEPVTSFHCEVVPKEPALVLKW-----ACPFGMYTGFEL 653
Query 557 FYRTIIGN-----ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
R+ + E + D + ++ L T Y + + A G P T
Sbjct 654 GVRSDSWDNMTRLENCTSDDDTECRTEVAYLNFSTSYNISI-ATLSCGKMALPAQNICT 711
>sp|P16170|NCA11_XENLA Neural cell adhesion molecule 1-A OS=Xenopus
laevis OX=8355 GN=ncam1-a PE=2 SV=1
Length=1088
Score = 88.4 bits (217), Expect = 2e-16, Method: Composition-based stats.
Identities = 73/429 (17%), Positives = 121/429 (28%), Gaps = 65/429 (15%)
Query 42 SNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTA-------SSVTFTDI 94
T C + I W+T I E T+ S++T DI
Sbjct 317 DEITLTC-------EASGDPIPSITWRTAVRNISSEATTLDGHIVVKEHIRMSALTLKDI 369
Query 95 ASLNI-QLTCNILTF-GQLEQNVYGITIISGLPPEK------------PKNLSCIVNEGK 140
+ + C G Q +Y P+ P N++C V
Sbjct 370 QYTDAGEYFCIASNPIGVDMQAMY---FEVQYAPKIRGPVVVYTWEGNPVNITCEVFAHP 426
Query 141 KMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
+ W + +NF+ ++ + + D+ F N A
Sbjct 427 RAAVTWFRDGQLLPSSNFSNIKIYSGPTSSSLEVNPDSEND---------FGNY--NCTA 475
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNI 259
N +G S+ I V+ + P + ++ E SS + + + P ILKY
Sbjct 476 INTIGHEFSEFIL------VQADTPSSPAIRKVEPYSSTVMIVFDEPDSTGGVPILKYKA 529
Query 260 QYRTKDASTWSQIPPEDTASTRSSF-TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
++R W + S TV LKP T Y+ ++ M G G S S+E +
Sbjct 530 EWRVIGHEKWHTKYYDAKEVNAESIITVMGLKPETSYMVKLSAMNGKGLGD-STPSQEFT 588
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR----WK 374
+ AP + + L + I Y V
Sbjct 589 TQPVREP--SAPKLVGHLSEDGNSIKVDI------LKQDDGGSPIRHYLVNYRALNALEW 640
Query 375 SHLQNYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA 432
N+ + + Y + N GKS A+L+
Sbjct 641 KPEMRVPSNSHHVMLKALEWNVDYEVIVVAENQQGKSKPALLSFRTTAKPTATTATASAG 700
Query 433 FPKDNMLWV 441
V
Sbjct 701 TGLGTGAIV 709
Score = 81.4 bits (199), Expect = 3e-14, Method: Composition-based stats.
Identities = 43/230 (19%), Positives = 77/230 (33%), Gaps = 15/230 (7%)
Query 380 YTVNATKLTVNL--TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN 437
++ L VN ND T N +G + + + A + K P +
Sbjct 451 SGPTSSSLEVNPDSENDFGNYNCTAINTIGHEFSEFILVQADTPSSPAI---RKVEPYSS 507
Query 438 MLWVEWTTPRE----SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
+ + + P + KY EW V+ + + ++ L Y+
Sbjct 508 TVMIVFDEPDSTGGVPILKYKAEWRVIGHEKWHTKYYDAKEVNAESIITVMGLKPETSYM 567
Query 494 ITVTPVYADGPGSPESIKAYLKQAP--PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
+ ++ + G G + + Q PS V N + D L D I
Sbjct 568 VKLSAMNGKGLGDSTPSQEFTTQPVREPSAPKLVGHLSEDGNSIKV--DILKQDDGGSPI 625
Query 552 RNYTIFYRTIIGNE--TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
R+Y + YR + E + V S+ L +L + Y V + A +G
Sbjct 626 RHYLVNYRALNALEWKPEMRVPSNSHHVMLKALEWNVDYEVIVVAENQQG 675
>sp|P0C0K7|EPHB6_RAT Ephrin type-B receptor 6 OS=Rattus norvegicus
OX=10116 GN=Ephb6 PE=3 SV=3
Length=1013
Score = 88.4 bits (217), Expect = 2e-16, Method: Composition-based stats.
Identities = 40/223 (18%), Positives = 70/223 (31%), Gaps = 25/223 (11%)
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL-----SDKAPCITDW------ 470
+L + + L + W P+E + L + V+ K P
Sbjct 362 GPPSAPRELWFEVQGSALMLHWRLPQELGGRGDLLFNVVCKECGGHKEPSSGGMCRRCRD 421
Query 471 -----QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPS 520
++ G L G L Y++ V V SP+ I PS
Sbjct 422 EVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPS 481
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTL 579
P + N + W Q + NG I +Y + +Y + + S T+
Sbjct 482 AVPVMHQVSRAANSITVSWPQ--PEQTNGNILDYQLRYYDQAEDESHSFTMTSETNTATV 539
Query 580 SSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAI 621
+ L+ +Y ++ A T G G + F T + +
Sbjct 540 TRLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLP 582
Score = 83.4 bits (204), Expect = 6e-15, Method: Composition-based stats.
Identities = 39/209 (19%), Positives = 69/209 (33%), Gaps = 29/209 (14%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD-----GGRETHLETNFTLKS-----EWATHKFADC-- 172
PP P+ L V +G + W GGR L + + C
Sbjct 363 PPSAPRELWFEV-QGSALMLHWRLPQELGGRGDLLFNVVCKECGGHKEPSSGGMCRRCRD 421
Query 173 -----KAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDH-----INFDPVYKVKP 222
+R S + V + V+A N + +++ D IN ++V
Sbjct 422 EVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPS 481
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P + ++ + ++W P + IL Y ++Y + S +
Sbjct 482 AVP---VMHQVSRAANSITVSWPQPEQTNGNILDYQLRYYDQAEDESHSFTM---TSETN 535
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+ TV L P Y F++R G G +
Sbjct 536 TATVTRLSPGHIYGFQVRARTAAGHGPYG 564
Score = 65.6 bits (158), Expect = 2e-09, Method: Composition-based stats.
Identities = 29/211 (14%), Positives = 55/211 (26%), Gaps = 29/211 (14%)
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
+ P P + QG + L W+ G +L + V H + +
Sbjct 355 PPEAPCTGPPSAPRELWFEVQGS-ALMLHWRLPQELGGRGDLL-FNVVCKECGGHKEPSS 412
Query 382 -------------------VNATKLTVNLTND--RYLATLTVRNLVGK-----SDAAVLT 415
+ +++ V Y+ + N V + AA +
Sbjct 413 GGMCRRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAIN 472
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
+ + + + N + V W E IL++ +
Sbjct 473 VSTSHEVPSAVPVMHQVSRAANSITVSW-PQPEQTNGNILDYQLRYYDQAEDESHSFTMT 531
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ T L+ Y V A G G
Sbjct 532 SETNTATVTRLSPGHIYGFQVRARTAAGHGP 562
Score = 57.2 bits (136), Expect = 7e-07, Method: Composition-based stats.
Identities = 44/238 (18%), Positives = 73/238 (31%), Gaps = 35/238 (15%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII-LKYNIQYRTKDA------- 266
DP PP + E S L L W P L +N+ +
Sbjct 354 DPPEAPCTGPPSAPRELWFEVQGSALMLHWRLPQELGGRGDLLFNVVCKECGGHKEPSSG 413
Query 267 ------STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
P T S V L+ Y+ ++ + G S +A+ I
Sbjct 414 GMCRRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVN--GVSELSPDPPQAAAI 471
Query 321 ---TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT---RWK 374
T + PS P + ++ ++ + W P + NG ILDY++ +
Sbjct 472 NVSTSHEVPSAVP-----VMHQVSRAANSITVSW--PQPEQTNGNILDYQLRYYDQAEDE 524
Query 375 SHLQNYTVNATKLTVNLTNDRYLA--TLTVRNLVGKSD----AAVLTIPACDFQATHP 426
SH T TV + ++ + R G T+P + + P
Sbjct 525 SHSFTMTSETNTATVTRLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLP 582
>sp|O35136|NCAM2_MOUSE Neural cell adhesion molecule 2 OS=Mus
musculus OX=10090 GN=Ncam2 PE=1 SV=1
Length=837
Score = 87.2 bits (214), Expect = 4e-16, Method: Composition-based stats.
Identities = 47/267 (18%), Positives = 79/267 (30%), Gaps = 20/267 (7%)
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
ND T N +G + A + H V ++ + + P
Sbjct 468 NDFGRYNCTATNRIGTRFQEYILELADVPSSPHGVKIIEL--SQTTAKISFNKPESHGGV 525
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
I + V + T V + +L + Y I V V G G I+
Sbjct 526 PIHHYQVDVKEVASETWKIVRSHGVQTMVVLSSLEPNTTYEIRVAAVNGKGQGDYSKIEI 585
Query 513 YLKQAPP---SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET--A 567
+ Q P P++ + + D I Y + YR+ +
Sbjct 586 F--QTLPVREPSPPSIHGQPSSGKSFKIS--ITKQDDGGAPILEYIVKYRSKDKEDQWLE 641
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK---------FAQGEI 618
V + L L Y V++ A G + + F+ P F +
Sbjct 642 KKVQGNKDHIILEHLQWTMGYEVQITAANRLGYSEPTVYEFSMPPKPNIIKDTLFNGLGL 701
Query 619 EAIVVPVCLAFLLTTLLGVLFCFNKRD 645
AI+ A LL ++ + CF R
Sbjct 702 GAIIGLGVAALLLILVVTDVSCFFIRQ 728
Score = 75.7 bits (184), Expect = 1e-12, Method: Composition-based stats.
Identities = 55/303 (18%), Positives = 95/303 (31%), Gaps = 50/303 (17%)
Query 129 PKNLSCIVNEGKKMRCEWDGGR-------ETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
P N+SC V W + THL+T+ + A +
Sbjct 417 PINISCDVTANPPASIHWRREKLLLPAKNTTHLKTHSV--GRKMILEIAPTSDNDFGRYN 474
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
C A N +G T + V P+ PH + +I + ++ +
Sbjct 475 C----------------TATNRIG--TRFQEYILELADV-PSSPHGVKIIELSQTTAKIS 515
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
S V I Y + + + TW + ++ + L+P T Y R+
Sbjct 516 FN-KPESHGGVPIHHYQVDVKEVASETWKIVRSHGV---QTMVVLSSLEPNTTYEIRVAA 571
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ G+G D+S+ T R PS PS + ++ + + + G
Sbjct 572 VNGKGQG---DYSKIEIFQTLPVREPSPPSI--HGQPSSGKSFK-ISIT-----KQDDGG 620
Query 362 -KILDYEVTLTRWKSHLQ----NYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAAVL 414
IL+Y V Q N + + Y +T N +G S+ V
Sbjct 621 APILEYIVKYRSKDKEDQWLEKKVQGNKDHIILEHLQWTMGYEVQITAANRLGYSEPTVY 680
Query 415 TIP 417
Sbjct 681 EFS 683
Score = 66.0 bits (159), Expect = 1e-09, Method: Composition-based stats.
Identities = 63/510 (12%), Positives = 129/510 (25%), Gaps = 76/510 (15%)
Query 40 LHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNI 99
T C I W N I + + I+ + + +T +I + +
Sbjct 224 RGEEMTLTC-------KASGSPDPTISWFRNGKLIEENEKYILKGSNTELTVRNIINKDG 276
Query 100 -QLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGK-----KMRCEWDGGRETH 153
C +Q + + +P L + CE E
Sbjct 277 GSYVCKATNKAGEDQKQAFLQVFV-----QPHILQLKNETTSENGHVTLVCE----AEGE 327
Query 154 LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV--------EAENALG 205
T K F++ D + +V + EA + +G
Sbjct 328 PVPEITWKRAIDGVMFSEGDKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRYDCEAASRIG 387
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD 265
++ + + +W + I + ++
Sbjct 388 GHQRSMHL-------------DIEYAPKFVSNQTMYYSWE----GNPINISCDVTANPPA 430
Query 266 ASTWSQIPPEDTASTRSSF--------TVQDLKPFTEYVF---RIRCMKEDGKGYWSDWS 314
+ W + A + + ++ P ++ F G +
Sbjct 431 SIHWRREKLLLPAKNTTHLKTHSVGRKMILEIAPTSDNDFGRYNCTATNRIGTRF----- 485
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWK 374
+ + D PS P I+ S T + P I Y+V +
Sbjct 486 -QEYILELADVPSS-PHGVKIIELSQTTAKISF-----NKPESHGGVPIHHYQVDVKEVA 538
Query 375 SHLQNYTVNA-----TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMD 429
S + L+ N Y + N G+ D + + I
Sbjct 539 SETWKIVRSHGVQTMVVLSSLEPNTTYEIRVAAVNGKGQGDYSKIEIFQTLPVREPSPPS 598
Query 430 LKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW-QQEDGTVHRTYLRGNLAE 488
+ P + T ++ ILE+ V W +++ + +L
Sbjct 599 IHGQPSSGKSFKISITKQDDGGAPILEYIVKYRSKDKEDQWLEKKVQGNKDHIILEHLQW 658
Query 489 SKCYLITVTPVYADGPGSPESIKAYLKQAP 518
+ Y + +T G P + + P
Sbjct 659 TMGYEVQITAANRLGYSEPTVYEFSMPPKP 688
>sp|Q90375|GHR_COLLI Growth hormone receptor OS=Columba livia
OX=8932 GN=GHR PE=2 SV=1
Length=611
Score = 86.4 bits (212), Expect = 4e-16, Method: Composition-based stats.
Identities = 36/201 (18%), Positives = 71/201 (35%), Gaps = 27/201 (13%)
Query 129 PKNLSCIVNEGKKMRCEW------DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSC 182
P+ C E + C W + ++ + +++ + D SC
Sbjct 29 PQISKCRSPELETFSCYWTDGNFYNLSAPGTIQLLYMKRNDEDWKECPDYI--TAGENSC 86
Query 183 TVDYS-TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS--- 238
+ S T ++ V + N D F V P+PP +L+ +
Sbjct 87 YFNTSYTSIWIPYCVKL--VNK--DEVFDEKCFSVDEIVLPDPPVHLNWTLLNTSQTGIH 142
Query 239 -ILKLTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
+++ W P V I L+Y +QY+ + + W ++ P + + LK
Sbjct 143 GDIQVRWDPPPTADVQKGWITLEYELQYKEVNETKWKELEPRL----STMVPLYSLKIGR 198
Query 294 EYVFRIRCMKEDG--KGYWSD 312
+Y R+R + G +S+
Sbjct 199 DYEIRVRSRQRTSEKFGEFSE 219
Score = 66.4 bits (160), Expect = 7e-10, Method: Composition-based stats.
Identities = 64/329 (19%), Positives = 113/329 (34%), Gaps = 48/329 (15%)
Query 519 PSKGPTVRTKKVGKNE------AVLEWDQLP-VDVQNGFIR-NYTIFYRTIIGNETAVNV 570
P + + ++ + WD P DVQ G+I Y + Y+ + +
Sbjct 123 PDPPVHLNWTLLNTSQTGIHGDIQVRWDPPPTADVQKGWITLEYELQYKEVNETKWKELE 182
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA------IVVP 624
T L SL Y +R+ + K G F+Q IE I P
Sbjct 183 PRLSTMVPLYSLKIGRDYEIRVRSRQRTSEKFGEFSEILYVSFSQAGIEFVHCAEEIEFP 242
Query 625 VCLAFLL----TTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF---- 676
L + + +L +K+ +K I+P VP P I P +
Sbjct 243 WFLVVIFGACGLAVTVILILLSKQSRLKMLIFPPVPVP---KIKGIDPDLLKKGKLDEVN 299
Query 677 -------NSKDQMYSDGNFTDVSVVEIE-ANDKKPFPEDLKSLDLFKKEKINTEGHSSGI 728
N K Q+Y+D + + ++IE ++K + + L + + G
Sbjct 300 SILASHDNYKTQLYNDDLWVEFIELDIEDPDEKNRVSDTDRLLSEDHLKSHSCLGAKDDD 359
Query 729 GG-SSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHS-------GYRHQVPSVQVFSRS 780
G +SC P S +++ S Q+ V G + S+ + +
Sbjct 360 SGRASCCEPDIPETDFS-ASDTCDAISDIDQFKKVTEKEEDLLCLGRKDNDESLPSLANT 418
Query 781 ESTQPLLDSEERPEDLQ----LVDHVDGG 805
++ QP + + RPE+ Q D +D
Sbjct 419 DTQQPRMST--RPENSQPWPPFADSIDAA 445
>sp|P70289|PTPRV_MOUSE Receptor-type tyrosine-protein phosphatase
V OS=Mus musculus OX=10090 GN=Ptprv PE=1 SV=1
Length=1705
Score = 87.2 bits (214), Expect = 4e-16, Method: Composition-based stats.
Identities = 92/572 (16%), Positives = 167/572 (29%), Gaps = 92/572 (16%)
Query 120 IISGLPPEKPKNLSC-IVNEGKKMRCEW---DGGRETHLETNFTLK-SEWATHKFADCKA 174
I S P P NLS ++ +R W GGR+ + L+ + K +A
Sbjct 559 IHSCTRPAPPTNLSLGFAHQPATLRASWCHPPGGRDAFQLRLYRLRPLTLESEKILSQEA 618
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
+ + E V+ G S + + P+ P ++V +
Sbjct 619 QNFSWAQLP--------AGYEFQVQLSTLWGSEESG--SANTTGWTPPSAPTLVNVTS-- 666
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
E + L ++W + + Y + + T + I ST L P T+
Sbjct 667 EAPTQLHVSWVHAAGDRS---SYQVTLYQESTRTATSIVGPKADSTSFW----GLTPGTK 719
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y ++ S +T + + S G V L W +
Sbjct 720 YKVEAISWAGPLYTAAANVSAWTYPLTPNE-----------LLASMQAGSAVVNLAWPSG 768
Query 355 PPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVL 414
P + W+ L L + + +L+V+ G
Sbjct 769 PLGRGTCHAQLSDAGHLSWEQPLSLGQDL---LMLRNLIPGHTVSLSVKCRAG--PLQAS 823
Query 415 TIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED 474
T P PV D+ P+ L + WT P V ++E L +Q
Sbjct 824 THPLVLSVEPGPVEDVFCQPEATYLSLNWTMPTGDVAVCLVEVEQLVPGGSAHFVFQVN- 882
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP----------- 523
T L NL + Y +++T + + S A P
Sbjct 883 -TSEDALLLPNLTPTTSYRLSLTVLGGNRQWSRAVTLVCTTSAEVWHPPELAEAPQVELG 941
Query 524 -----TVRTKKVGKNEAVLEWDQL---------PVDVQNGFIRNYTIFYR-------TII 562
TV GK++ ++W + + Y +YR +
Sbjct 942 TGMGVTVTRGMFGKDDGQIQWYGIIATINMTLAQPSQEAINHTWYDHYYRGHDSYLALLF 1001
Query 563 GNETAVNVDSSHTEYTLS---------------SLTSDTLYMVRMAAYTDEGGKDGPEFT 607
N + +T+ L Y +AA++ PE
Sbjct 1002 PNPFYPEPWAVPRSWTVPVGTEDCDNTQEICNGHLKPGFQYRFSIAAFSR---LSSPETI 1058
Query 608 FTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLF 639
F++ + +V + L ++ T++G +
Sbjct 1059 LAFSAFSEPQASISLVAMPLTVMMGTVVGCII 1090
Score = 75.3 bits (183), Expect = 2e-12, Method: Composition-based stats.
Identities = 74/480 (15%), Positives = 145/480 (30%), Gaps = 59/480 (12%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGR---ETHLETNFTLKSEWATHKFADCKAKRDTPT 180
LPP+ + +S N + W E + T S+ + D + T
Sbjct 474 LPPQSLEIIS--RNSPSDLTIGWAPAPGQMEGYKVTWHQDGSQRSPGDLVDLGPDISSLT 531
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
++ + Y V+ W G ++SD + P PP NLS+ + + + L
Sbjct 532 LKSLVPGSCYTVSAWAWS------GNLSSDSQKIHSCTR--PAPPTNLSLGFAHQ-PATL 582
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
+ +W +P + R + + E + + Y F+++
Sbjct 583 RASWCHPPGGRDAFQLRLYRLRPLTLESEKILSQEAQNFSWAQLPAG-------YEFQVQ 635
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
G S+ S A+ + P AP+ + TQ + + W A
Sbjct 636 LSTLWG----SEESGSANTTGW--TPPSAPTLVNVTSEAPTQ----LHVSW-----VHAA 680
Query 361 GKILDYEVTLTRWKSHLQNYTV----NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
G Y+VTL + + V ++T +Y + + G A +
Sbjct 681 GDRSSYQVTLYQESTRTATSIVGPKADSTSFWGLTPGTKYK--VEAISWAGPLYTAAANV 738
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
A + T + ++ + W P + + C W+Q
Sbjct 739 SAWTYPLTPNELLASMQAGSAVVNLAW--PSGPLGRGT---CHAQLSDAGHLSWEQPLSL 793
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAV 536
+ NL ++V S + ++ P V +
Sbjct 794 GQDLLMLRNLIPGHTVSLSVKCRAGPLQASTHPLVLSVE---PGPVEDVFCQ-PEATYLS 849
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGN---ETAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
L W + G + + ++ V++S L +LT T Y + +
Sbjct 850 LNW-----TMPTGDVAVCLVEVEQLVPGGSAHFVFQVNTSEDALLLPNLTPTTSYRLSLT 904
Score = 74.5 bits (181), Expect = 4e-12, Method: Composition-based stats.
Identities = 52/330 (16%), Positives = 83/330 (25%), Gaps = 39/330 (12%)
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
+S + T L P Y I D ++ +G T P
Sbjct 433 SVSSGATHVTFCGLVPGAHYRVDIASSM-------GDITQSLTGYTSPLPPQS------- 478
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL-----TRWKSHLQNYTVNATKLTVN 390
++ + + W P G++ Y+VT R L + + + LT+
Sbjct 479 LEIISRNSPSDLTIGWAPAP-----GQMEGYKVTWHQDGSQRSPGDLVDLGPDISSLTLK 533
Query 391 LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV 450
T++ G + I +C A + L + L W P
Sbjct 534 SLVPGSCYTVSAWAWSGNLSSDSQKIHSCTRPAPPTNLSLGFAHQPATLRASWCHPPGGR 593
Query 451 KKYILE-WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES 509
+ L + + QE L Y V G S
Sbjct 594 DAFQLRLYRLRPLTLESEKILSQEAQNFSWAQLPAG------YEFQVQLSTLWGSEESGS 647
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
PPS V + + W G +Y +
Sbjct 648 AN-TTGWTPPSAPTLVNVTSEAPTQLHVSWVH-----AAGDRSSYQVTLYQESTRTATSI 701
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
V + LT T Y V A + G
Sbjct 702 VGPKADSTSFWGLTPGTKYKVE--AISWAG 729
Score = 57.6 bits (137), Expect = 5e-07, Method: Composition-based stats.
Identities = 66/460 (14%), Positives = 122/460 (27%), Gaps = 54/460 (12%)
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
+ W + L++ + + + T S + V ++ +
Sbjct 49 PTSLFLSWVAAEPGGFDYALCLRAMNLSGFPEGQQLQAHTNESSFEFHGLVPGSRYQLEL 108
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
+ ++ + P L + +S + L+ +W S S Y
Sbjct 109 TVLRPCWQ----NVTITLTARTAPTVVRGLQL-HSTGSPASLEASW---SDASGDQDSYQ 160
Query 259 IQ-YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS--DWSE 315
+ Y + + + + S+ DL P ++YV + S W+E
Sbjct 161 LLLYHPESHTLACNV---SVSPDTLSYNFGDLLPGSQYVLEVITWAGSLHAKTSILQWTE 217
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
P G ++Q W + IL + T
Sbjct 218 PV-----------PPDHLRV----RALGTSSLQAFWNSSEGATWFHLILTDLLEGTNLTK 262
Query 376 HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK 435
++ T Y + + A ++ DL P
Sbjct 263 VVRQGISTHT-FLRLSPGTPYQLKICAA----AGPHQIWGPNATEWTYPSYPSDLVLTPL 317
Query 436 DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLIT 495
N LW W + + Y+L+ LS T G L Y +
Sbjct 318 WNELWASWKAGQGARDGYVLK---LSGPVENTT---TLGPEECNAVFPGPLPPG-HYTLG 370
Query 496 VTPVYA-DGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
+ + SI A P + P R G Y
Sbjct 371 LRVLAGPYDAWVEGSIWLAESAARPMEVPGARLWLEGLEA---------TKQPGRRALLY 421
Query 555 TIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
++ ++GN ++V S T T L Y V +A+
Sbjct 422 SVDAPGLLGN---ISVSSGATHVTFCGLVPGAHYRVDIAS 458
>sp|A3KN33|EGFLA_BOVIN Pikachurin OS=Bos taurus OX=9913 GN=EGFLAM
PE=2 SV=1
Length=1018
Score = 86.4 bits (212), Expect = 6e-16, Method: Composition-based stats.
Identities = 49/251 (20%), Positives = 81/251 (32%), Gaps = 32/251 (13%)
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY------RTK 264
+ + K PP ++ + S + W P I+ Y + Y ++
Sbjct 24 PLRSALRKQGKVGPPLDIILDALNC--SAFSIQWKMPRHPPSPIMGYTVFYSEVGIDKSL 81
Query 265 DASTWSQIPPEDTASTRS-------SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
++ P DT ++ + DLKP TEY + + GKG S S +
Sbjct 82 QERSYGVPPGLDTPTSGRLDHQMIFEEVIGDLKPGTEYRVSMAAYSQTGKGRLS--SPQH 139
Query 318 SGITYEDR--PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR--- 372
+D P AP + I S + V L WK E + I Y V TR
Sbjct 140 VTTLPQDSCLPPTAPQQPHVIVVSDS----EVALSWKPG-ESEGSSPIQYYSVEFTRPDF 194
Query 373 ---WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD--AAVLTIPACDFQATHPV 427
W S + +++ + + Y + N G S TI + +
Sbjct 195 DKSWTSIREQIQMDSMVIKGLDPDTNYQFAVRAVNPHGSSPRSQPSSTIRTARPEESGSG 254
Query 428 MDLKAFPKDNM 438
+ D
Sbjct 255 RYGPHYATDTE 265
Score = 85.7 bits (210), Expect = 1e-15, Method: Composition-based stats.
Identities = 35/223 (16%), Positives = 66/223 (30%), Gaps = 27/223 (12%)
Query 420 DFQATHPVMDLKAFPKDNMLWVEWT---TPRESVKKYILEWCVLS-DKAPCITDWQQEDG 475
+ P+ + + ++W P + Y + + + DK+ + G
Sbjct 32 QGKVGPPLDIILDALNCSAFSIQWKMPRHPPSPIMGYTVFYSEVGIDKSLQERSYGVPPG 91
Query 476 TVHRT-----------YLRGNLAESKCYLITVTPVYADGPG--SPESIKAYLKQ---APP 519
T + G+L Y +++ G G S L Q PP
Sbjct 92 LDTPTSGRLDHQMIFEEVIGDLKPGTEYRVSMAAYSQTGKGRLSSPQHVTTLPQDSCLPP 151
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSHTEY 577
+ V +E L W + I+ Y++ + + T++
Sbjct 152 TAPQQPHVIVVSDSEVALSWKPG-ESEGSSPIQYYSVEFTRPDFDKSWTSIREQIQMDSM 210
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKD--GPEFTFTT--PKFAQG 616
+ L DT Y + A G P T T P+ +
Sbjct 211 VIKGLDPDTNYQFAVRAVNPHGSSPRSQPSSTIRTARPEESGS 253
Score = 78.0 bits (190), Expect = 3e-13, Method: Composition-based stats.
Identities = 40/220 (18%), Positives = 71/220 (32%), Gaps = 27/220 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGR-ETHLETNFTLKSEWAT------HKFADCKAKRDTP 179
P ++ +W R +T+ + DTP
Sbjct 36 GPPLDIILDALNCSAFSIQWKMPRHPPSPIMGYTVFYSEVGIDKSLQERSYGVPPGLDTP 95
Query 180 TSCTVDYSTVYF---------VNIEVWVEAENALGKVT-SDHINFDPVYK---VKPNPPH 226
TS +D+ ++ V + A + GK S + + + + P P
Sbjct 96 TSGRLDHQMIFEEVIGDLKPGTEYRVSMAAYSQTGKGRLSSPQHVTTLPQDSCLPPTAPQ 155
Query 227 NLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQY-RTKDASTWSQIPPEDTASTRSSF 284
VI + S + L+W S S I Y++++ R +W+ I + S
Sbjct 156 QPHVIVVSD--SEVALSWKPGESEGSSPIQYYSVEFTRPDFDKSWTSIREQI---QMDSM 210
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
++ L P T Y F +R + G S S E+
Sbjct 211 VIKGLDPDTNYQFAVRAVNPHGSSPRSQPSSTIRTARPEE 250
Score = 66.8 bits (161), Expect = 9e-10, Method: Composition-based stats.
Identities = 31/198 (16%), Positives = 52/198 (26%), Gaps = 29/198 (15%)
Query 349 LVWKTLPPFEANGKILDYEVTLTR----WKSHLQNYTVN---ATKLTVNL---------- 391
+ WK P I+ Y V + ++Y V T + L
Sbjct 53 IQWK--MPRHPPSPIMGYTVFYSEVGIDKSLQERSYGVPPGLDTPTSGRLDHQMIFEEVI 110
Query 392 ----TNDRYLATLTVRNLVGK----SDAAVLTIPACD-FQATHPVMDLKAFPKDNMLWVE 442
Y ++ + GK S V T+P T P D+ + +
Sbjct 111 GDLKPGTEYRVSMAAYSQTGKGRLSSPQHVTTLPQDSCLPPTAPQQPHVIVVSDSEVALS 170
Query 443 WTTPRESVKKYILEWCVLSDKAPCITDWQQE-DGTVHRTYLRGNLAESKCYLITVTPVYA 501
W I + V + W + + + L Y V V
Sbjct 171 WKPGESEGSSPIQYYSVEFTRPDFDKSWTSIREQIQMDSMVIKGLDPDTNYQFAVRAVNP 230
Query 502 DGPGSPESIKAYLKQAPP 519
G + ++ A P
Sbjct 231 HGSSPRSQPSSTIRTARP 248
Score = 41.4 bits (95), Expect = 0.044, Method: Composition-based stats.
Identities = 16/92 (17%), Positives = 26/92 (28%), Gaps = 2/92 (2%)
Query 122 SGLPPEKPKNLSCIVNEGKKMRCEWDGG-RETHLE-TNFTLKSEWATHKFADCKAKRDTP 179
S LPP P+ IV ++ W G E ++++ + +
Sbjct 147 SCLPPTAPQQPHVIVVSDSEVALSWKPGESEGSSPIQYYSVEFTRPDFDKSWTSIREQIQ 206
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDH 211
V N + V A N G
Sbjct 207 MDSMVIKGLDPDTNYQFAVRAVNPHGSSPRSQ 238
>sp|P20806|7LESS_DROVI Protein sevenless OS=Drosophila virilis
OX=7244 GN=sev PE=3 SV=1
Length=2594
Score = 86.8 bits (213), Expect = 8e-16, Method: Composition-based stats.
Identities = 55/308 (18%), Positives = 100/308 (32%), Gaps = 30/308 (10%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK-YNIQYRTKD---ASTWSQIPPE 275
V+ P L + + SS L + W ++ + + +NIQY+ D W +
Sbjct 357 VETTQPQLLEMTDE---SSTLTIKWAMQFPENYLASRPFNIQYQQVDNQSEPEWHNLADY 413
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD-----WSEEASGITYEDRPSKAP 330
D ++ L P+T Y FR E G S+ + E P AP
Sbjct 414 DCDEYYVCEILEALVPYTRYKFR----FELPFGESSEDVLYSPATPVYETPMEGAPISAP 469
Query 331 SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV- 389
+ V + W+ P +N I Y V LT + + + A + +
Sbjct 470 IIVALL----ALDEHHVFVHWR--PGRYSNAPIEGYRVLLTSAGNTSREQLLPAQRTSCI 523
Query 390 ---NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
Y LT+ N G+ + V++I + + + +++W
Sbjct 524 FAQLQPLTNYTVALTMINKQGEGPSTVVSIVTKSPLEPQQLQSVLLASEHSIIWQSLEPA 583
Query 447 RESVKKYILEWCVLSD---KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT-PVYAD 502
E+ Y E +SD W ++ + L S + + P
Sbjct 584 GETRLLYTSEPAAISDFTFSQREQRLWLLDELGQLHSQLLDETTTSAARRLRLELPSNGS 643
Query 503 GPGSPESI 510
+P +
Sbjct 644 SQWTPRKL 651
Score = 66.8 bits (161), Expect = 9e-10, Method: Composition-based stats.
Identities = 24/212 (11%), Positives = 51/212 (24%), Gaps = 14/212 (7%)
Query 427 VMDLKAFPKDNMLWVEW--TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY--- 481
L+ + + L ++W P + +W Y
Sbjct 362 PQLLEMTDESSTLTIKWAMQFPENYLASRPFNIQYQQVDNQSEPEWHNLADYDCDEYYVC 421
Query 482 -LRGNLAESKCYLITVTPVYADG-----PGSPESIKAYLKQAPPSKGPT-VRTKKVGKNE 534
+ L Y + + + + P P V + ++
Sbjct 422 EILEALVPYTRYKFRFELPFGESSEDVLYSPATPVYETPMEGAPISAPIIVALLALDEHH 481
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
+ W P N I Y + + + + T + L T Y V +
Sbjct 482 VFVHWR--PGRYSNAPIEGYRVLLTSAGNTSREQLLPAQRTSCIFAQLQPLTNYTVALTM 539
Query 595 YTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVC 626
+G + T + + V+
Sbjct 540 INKQGEGPSTVVSIVTKSPLEPQQLQSVLLAS 571
Score = 57.2 bits (136), Expect = 8e-07, Method: Composition-based stats.
Identities = 29/197 (15%), Positives = 56/197 (28%), Gaps = 33/197 (17%)
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
+ + N V W P S + + + +L +
Sbjct 1224 VRPLAVPPDSVHIDEGGHWNDFRVRWQ-PAASGGNHSVCYKLLLEHGS------------ 1270
Query 478 HRTYLRGNLAESKC----------YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
R L I++TP A GS ++ A P++ +R
Sbjct 1271 ERLITLELLTPFARITQLAQAPLGLRISITPHTAWRAGSTTRVQLDTPVAAPTQPRRLRV 1330
Query 528 ---------KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
+ A+L WD +P + Y I + + ++ S E
Sbjct 1331 FVERQAAPLQLAPNVSALLRWD-VPEEHAGSQSLQYRISCWRGSELHSELLLNQSTLEAR 1389
Query 579 LSSLTSDTLYMVRMAAY 595
+ L + Y ++ A+
Sbjct 1390 VEHLQPEETYRFQVQAH 1406
Score = 53.7 bits (127), Expect = 8e-06, Method: Composition-based stats.
Identities = 43/253 (17%), Positives = 70/253 (28%), Gaps = 34/253 (13%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRET-HLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P P+N S ++ W E +TL + + ++
Sbjct 1819 PSAPRNFSGRALSPSELELSWLAPLELRSASVYYTLHWQLQLEDTEEQSQEQPAQEQRVE 1878
Query 185 DYSTVYFVN------IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
+VW++A K S Y P PP L E +
Sbjct 1879 TAGVQRLTGLQPARLYQVWLQAHATPSKYNSSGRLLIRSY--APLPPLQL----IELNAY 1932
Query 239 ILKLTWT-NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ L W P S + L+ + + + A + + L+P T Y
Sbjct 1933 GMTLAWPGTPDALSSLTLECQ---------SLREQLQFNVAGNHTQMRLAPLQPKTRYSC 1983
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV-QLVWKTLPP 356
R+ G + T D PS P + ++ W P
Sbjct 1984 RLALAYAATPGAPIYFGPSHEYETLGDAPSAP------GRPQLEHIAGEIFRVSWT---P 2034
Query 357 FEANG-KILDYEV 368
NG IL Y +
Sbjct 2035 ALDNGSPILLYNL 2047
Score = 52.2 bits (123), Expect = 3e-05, Method: Composition-based stats.
Identities = 49/284 (17%), Positives = 85/284 (30%), Gaps = 44/284 (15%)
Query 362 KILDYEVTLTRWKSHLQ---NYTVNATKLTVNL----TNDRYLATLTVRN----LVGKSD 410
L+Y++ L+ Q +A LT+N+ Y V + +G+
Sbjct 1745 PGLNYQLNLSSSSRSAQLELRSLHSAAGLTLNISQLQPYQAYELRAQVGSYYQQQLGQEP 1804
Query 411 AAVLTIPACDFQATH-PVMDLKAFPKD-NMLWVEWTTPRE---SVKKYILEWCVLSDKAP 465
+ + AT + + L + W P E + Y L W + +
Sbjct 1805 LQLPVLTLHTAAATPSAPRNFSGRALSPSELELSWLAPLELRSASVYYTLHWQLQLEDTE 1864
Query 466 CITDWQQEDGTVHRT---YLRGNLAESKCYLITVTP------VYADGPGSPESIKAYLKQ 516
+ Q T L ++ Y + + + G S
Sbjct 1865 EQSQEQPAQEQRVETAGVQRLTGLQPARLYQVWLQAHATPSKYNSSGRLLIRSY------ 1918
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
P P ++ ++ L W P D + + + NV +HT+
Sbjct 1919 -APL--PPLQLIELNAYGMTLAWPGTP-DALSSLTLE-----CQSLREQLQFNVAGNHTQ 1969
Query 577 YTLSSLTSDTLYMVRMA-AYTDEGGKD---GPEFTFTTPKFAQG 616
L+ L T Y R+A AY G GP + T A
Sbjct 1970 MRLAPLQPKTRYSCRLALAYAATPGAPIYFGPSHEYETLGDAPS 2013
Score = 47.9 bits (112), Expect = 5e-04, Method: Composition-based stats.
Identities = 33/215 (15%), Positives = 76/215 (35%), Gaps = 33/215 (15%)
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD-------HINFDPVYKVKPNPPHNLS 229
D C + + V + + E G+ + D + P+ + P ++
Sbjct 416 DEYYVCEILEALVPYTRYKFRFEL--PFGESSEDVLYSPATPVYETPMEGAPISAPIIVA 473
Query 230 VINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
++ +E + + W + I Y + + ++ Q+ P + R+S L
Sbjct 474 LLALDEH--HVFVHWRPGRYSNAPIEGYRVLLTSAGNTSREQLLP----AQRTSCIFAQL 527
Query 290 KPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
+P T Y + + + G+G S S +T P + + S +
Sbjct 528 QPLTNYTVALTMINKQGEG----PSTVVSIVT--KSPLEPQQLQSVLLASEHS------I 575
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA 384
+W++L E G+ + T + + ++T +
Sbjct 576 IWQSL---EPAGETR---LLYTSEPAAISDFTFSQ 604
Score = 46.8 bits (109), Expect = 0.001, Method: Composition-based stats.
Identities = 42/282 (15%), Positives = 75/282 (27%), Gaps = 40/282 (14%)
Query 65 IVWKTNHFTIP--------KEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVY 116
+ W+ +EQ + L +
Sbjct 1854 LHWQLQLEDTEEQSQEQPAQEQRVETAGVQRLTGLQPARLYQVWLQAHATPSKYNSS--- 1910
Query 117 GITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKR 176
G +I P P L + G M W G L + TL+ + + A
Sbjct 1911 GRLLIRSYAPLPPLQLIELNAYG--MTLAW-PGTPDALS-SLTLECQSLREQLQFNVAGN 1966
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
T + A + + P+ P + +
Sbjct 1967 HTQMRLAPLQPKTRYSCRLALAYAATPGAPIYFGPSHEYETLGDAPSAPGRPQLEHIAGE 2026
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDAS---------------TWSQIP-------P 274
I +++WT IL YN++ + W++ P
Sbjct 2027 --IFRVSWTPALDNGSPILLYNLEALQARRTNRRRRRRRETTLSLLPWAEEPLVIEDQWL 2084
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKE-DGKGYWSDWSE 315
+ +T S V++L +FR+R G G +S+ SE
Sbjct 2085 DFCNTTELSCIVRELHTRRLLLFRVRARNRPHGWGPYSEDSE 2126
Score = 44.5 bits (103), Expect = 0.006, Method: Composition-based stats.
Identities = 21/169 (12%), Positives = 45/169 (27%), Gaps = 15/169 (9%)
Query 142 MRCEWDGGRETH-LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
R W + L E + + + + + + + + +
Sbjct 1245 FRVRWQPAASGGNHSVCYKLLLEHGSERLITLELLTPFARITQLAQAPL---GLRISITP 1301
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS-------ILKLTWTNPSIKSVI 253
A ++ + D P P L V + + L W P +
Sbjct 1302 HTAWRAGSTTRVQLD-TPVAAPTQPRRLRVFVERQAAPLQLAPNVSALLRWDVPEEHAGS 1360
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
++QYR + V+ L+P Y F+++
Sbjct 1361 Q---SLQYRISCWRGSELHSELLLNQSTLEARVEHLQPEETYRFQVQAH 1406
Score = 40.6 bits (93), Expect = 0.082, Method: Composition-based stats.
Identities = 52/415 (13%), Positives = 96/415 (23%), Gaps = 61/415 (15%)
Query 148 GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA----ENA 203
L L S + + + + + E+ + +
Sbjct 1741 PLPVPGLNYQLNLSSSSRSAQLELRSLHSAAGLTLNIS-QLQPYQAYELRAQVGSYYQQQ 1799
Query 204 LGKVTSD-HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY----N 258
LG+ + P+ P N S S L+L+W P + Y
Sbjct 1800 LGQEPLQLPVLTLHTAAATPSAPRNFS--GRALSPSELELSWLAPLELRSASVYYTLHWQ 1857
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+Q + + Q E T + L+P Y ++ S ++
Sbjct 1858 LQLEDTEEQSQEQPAQEQRVETAGVQRLTGLQPARLYQVWLQA-----HATPSKYNSSGR 1912
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
+ P + L W P +A + + + LQ
Sbjct 1913 LLIRSYAPLPPLQL-------IELNAYGMTLAWPGTP--DALSSLT---LECQSLREQLQ 1960
Query 379 -NYTVNATK--LTVNLTNDRYLATLTVRNLVGKSDAAVLTIP----ACDFQATHPVMDLK 431
N N T+ L RY L + + P
Sbjct 1961 FNVAGNHTQMRLAPLQPKTRYSCRLALAYAATPGAPIYFGPSHEYETLGDAPSAPGRPQL 2020
Query 432 AFPKDNMLWVEWTTPRESVKKYILE-------------WCVLSDKAPCITDWQQED---- 474
+ V WT ++ +L + + W +E
Sbjct 2021 EHIAGEIFRVSWTPALDNGSPILLYNLEALQARRTNRRRRRRRETTLSLLPWAEEPLVIE 2080
Query 475 -------GTVHRTYLRGNLAESKCYLITVTPVY-ADGPGSPESIKAYLKQAPPSK 521
T + + L + L V G G + + S
Sbjct 2081 DQWLDFCNTTELSCIVRELHTRRLLLFRVRARNRPHGWGPYSEDSERIAEPFVSP 2135
>sp|P22648|FAS2_SCHAM Fasciclin-2 OS=Schistocerca americana OX=7009
GN=FAS2 PE=1 SV=2
Length=898
Score = 86.1 bits (211), Expect = 8e-16, Method: Composition-based stats.
Identities = 57/331 (17%), Positives = 98/331 (30%), Gaps = 57/331 (17%)
Query 130 KNLSCIVNEGKKMRCEWD-------GGRETH--LETNFTLKSEWATHKFADCKAKRDTPT 180
NL+C+ + W GRE +T +TL
Sbjct 446 VNLTCLAHSIPNATISWHFNGADLFRGREGQELQQTGYTLFGSGPRSTLQ---------- 495
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
+ ++ + N + A N G T+ H +V P L V ++ +
Sbjct 496 --VIPFNRKMYGNYK--CTATNKHG--TAVHEIMLREARV---PSAVLQVKMDVMTATTV 546
Query 241 KLTWTNPSIKSVIILK-YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ P + K Y +QY+ +D+ W T S + +++LKP T Y FR
Sbjct 547 TFKFFGPGNDGGLPTKNYAVQYK-QDSQGWED-ALNRTWPVDSPYILENLKPQTRYNFRF 604
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ--------LVW 351
E G G WS S++ P + + + V L W
Sbjct 605 AAQNEVGFGPWS--SQQTHTTPRISAPEEPRLLGLPLSATSGTENEVVVSPYPNRYELRW 662
Query 352 KTLPPFEANGKILDYEVTLT--------------RWKSHLQNYTVNATKLTVNLTNDRYL 397
+ P + I Y V + H +L + Y
Sbjct 663 QV--PADNGEPITHYSVKSCPVEKYDTEWRLLPYPCQEHKLEGQATTFQLESLQPDTHYK 720
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+ N +G S + + + P +
Sbjct 721 VEVRATNAIGNSVPGQIIVRTVKDPSQMPGV 751
Score = 82.2 bits (201), Expect = 1e-14, Method: Composition-based stats.
Identities = 47/279 (17%), Positives = 77/279 (28%), Gaps = 46/279 (16%)
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA 423
Y + + +S LQ N T N G AV I + +
Sbjct 481 TGYTLFGSGPRSTLQVIPFN--------RKMYGNYKCTATNKHGT---AVHEIMLREARV 529
Query 424 THPVMDLK--AFPKDNMLWVEWTTPRE---SVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
V+ +K + + + + K Y +++ S D V
Sbjct 530 PSAVLQVKMDVMTATTVTFKFFGPGNDGGLPTKNYAVQYKQDSQGWE---DALNRTWPVD 586
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ--APPSKG-------------P 523
Y+ NL Y G G S + + + P +
Sbjct 587 SPYILENLKPQTRYNFRFAAQNEVGFGPWSSQQTHTTPRISAPEEPRLLGLPLSATSGTE 646
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF----------YRTIIGNETAVNVDSS 573
N L W Q+P D I +Y++ +R + ++
Sbjct 647 NEVVVSPYPNRYELRW-QVPADNGE-PITHYSVKSCPVEKYDTEWRLLPYPCQEHKLEGQ 704
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
T + L SL DT Y V + A G + T K
Sbjct 705 ATTFQLESLQPDTHYKVEVRATNAIGNSVPGQIIVRTVK 743
>sp|Q8BYG9|EPHAA_MOUSE Ephrin type-A receptor 10 OS=Mus musculus
OX=10090 GN=Epha10 PE=2 SV=2
Length=1007
Score = 86.1 bits (211), Expect = 9e-16, Method: Composition-based stats.
Identities = 39/269 (14%), Positives = 80/269 (30%), Gaps = 32/269 (12%)
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL-------- 460
S + + + L + W P +S + + + +L
Sbjct 325 SPTDPPSASCTRPPSAPRDLQYSLSRSPLALRLRWLPPADSGGRSDVTYSLLCLRCGRDG 384
Query 461 -----SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP------GSPES 509
P + ++ G R +L Y + V + +
Sbjct 385 PAGACQPCGPRVAFVPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGATYAQ 444
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEW-DQLPVDVQNGFIRNYTI-FYRTIIGNETA 567
+ P + +R +V L W + +P Y I +Y +T
Sbjct 445 VTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPVPAGAPGTNSTEYEIRYYEKGQSEQTY 504
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTD----EGGKDGPEFTFTTP-KFAQGE----- 617
V + T+++L T Y+ ++ A + E P TP + A G
Sbjct 505 STVKTGAPAVTVTNLKPATRYVFQIRAASPGPLWEAQSFSPSIEVQTPGEVAPGSRDQSP 564
Query 618 -IEAIVVPVCLAFLLTTLLGVLFCFNKRD 645
+ VV + +L +++ VL + +
Sbjct 565 AVVVTVVTISALLVLGSVMSVLAIWRRPC 593
Score = 80.3 bits (196), Expect = 5e-14, Method: Composition-based stats.
Identities = 38/224 (17%), Positives = 64/224 (29%), Gaps = 25/224 (11%)
Query 125 PPEKPKNLS-CIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHK-----FADCKAKR 176
PP P++L + +R W ++ + ++L C +
Sbjct 337 PPSAPRDLQYSLSRSPLALRLRWLPPADSGGRSDVTYSLLCLRCGRDGPAGACQPCGPRV 396
Query 177 DT---PTSCTVDYSTVYFVN----IEVWVEAENALG--KVTSDHINFDPVYKVKPNPPHN 227
+T+ + V V A N + + P P
Sbjct 397 AFVPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGATYAQVTVSTGPGAPWE 456
Query 228 L-SVINSEELSSILKLTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
+ + L+W P +Y I+Y K S+ + +
Sbjct 457 EDEIRRDRVEPQSVSLSWREPVPAGAPGTNSTEYEIRYYEKG---QSEQTYSTVKTGAPA 513
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY-EDRP 326
TV +LKP T YVF+IR +S T E P
Sbjct 514 VTVTNLKPATRYVFQIRAASPGPLWEAQSFSPSIEVQTPGEVAP 557
Score = 54.1 bits (128), Expect = 6e-06, Method: Composition-based stats.
Identities = 37/266 (14%), Positives = 73/266 (27%), Gaps = 49/266 (18%)
Query 315 EEASGITYEDRPS----KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI-LDYEVT 369
++ + D PS + PS + S ++ ++L W LPP ++ G+ + Y +
Sbjct 319 QDTYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLALRLRW--LPPADSGGRSDVTYSLL 376
Query 370 LTRWKSHLQNYTVN------------------ATKLTVNLTNDRYLATLTVRNLVGKSDA 411
R A L RY + N V A
Sbjct 377 CLRCGRDGPAGACQPCGPRVAFVPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAA 436
Query 412 AV------LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES------VKKYILEWCV 459
A +T+ + + + + W P + +Y + +
Sbjct 437 AAGATYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPVPAGAPGTNSTEYEIRYYE 496
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY----ADGPGSPESIKAYLK 515
+ + V T NL + Y+ + + SI+
Sbjct 497 KGQSEQTYSTVKTGAPAVTVT----NLKPATRYVFQIRAASPGPLWEAQSFSPSIEVQTP 552
Query 516 -QAPPSKG---PTVRTKKVGKNEAVL 537
+ P P V V + ++
Sbjct 553 GEVAPGSRDQSPAVVVTVVTISALLV 578
>sp|B3EX02|MFP1_ACRMI MAM and fibronectin type III domain-containing
protein 1 (Fragment) OS=Acropora millepora OX=45264 PE=1
SV=1
Length=422
Score = 84.1 bits (206), Expect = 1e-15, Method: Composition-based stats.
Identities = 43/239 (18%), Positives = 85/239 (36%), Gaps = 11/239 (5%)
Query 377 LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD-AAVLTIPACDFQATHPVMDLKAFP- 434
+N+T N + +++ N + + + P +
Sbjct 146 NENHTSNTFLEITFQESQNVTIQVSLENNQSYARFGYGILEGGLESALLLPGWNASLENK 205
Query 435 KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
L + W ++ + + V + + + + L Y +
Sbjct 206 TSTSLQLRWMDISSWLRDGLRFFVVTAKSSYSNLTVKGLFSSNTTFAEISGLDPYMAYDV 265
Query 495 TVTPVYADGPGSPESI-KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
+V V DG ++ +A + PS+ P+V V ++W+ LP NG +
Sbjct 266 SVVAVDGDGSQFKSTVLQARTDEWVPSRAPSVFVTSVTSTSVTVQWNPLPQQYHNGRLLG 325
Query 554 YTIFYR-----TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
Y +F R +E+ V V + + TL++L Y V ++A+T +G DGP T
Sbjct 326 YRVFIRKTANSPFPLDESNVAV-YNTSWVTLNNLKPGQPYEVNVSAFTSKG--DGPRST 381
Score = 77.2 bits (188), Expect = 2e-13, Method: Composition-based stats.
Identities = 39/216 (18%), Positives = 75/216 (35%), Gaps = 20/216 (9%)
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF-TVQDLKP 291
+ S+ L+L W + S L++ + S++S + + S+ ++F + L P
Sbjct 203 ENKTSTSLQLRWMDISSWLRDGLRFFV---VTAKSSYSNLTVKGLFSSNTTFAEISGLDP 259
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
+ Y + + DG + S T E PS+APS + S + + W
Sbjct 260 YMAYDVSVVAVDGDGSQF---KSTVLQARTDEWVPSRAPSVFVTSVTSTSVTVQ-----W 311
Query 352 KTLPPFEANGKILDYEVTLTRWKS------HLQNYTVNATKLTVNLTN--DRYLATLTVR 403
LP NG++L Y V + + + N + +T+N Y ++
Sbjct 312 NPLPQQYHNGRLLGYRVFIRKTANSPFPLDESNVAVYNTSWVTLNNLKPGQPYEVNVSAF 371
Query 404 NLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNML 439
G + I P + +
Sbjct 372 TSKGDGPRSTHYIVTTAVCGKRPTHSTLNCRRHSST 407
Score = 56.4 bits (134), Expect = 6e-07, Method: Composition-based stats.
Identities = 28/184 (15%), Positives = 61/184 (33%), Gaps = 11/184 (6%)
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN---YTVNAT--KLTVNLTNDR 395
+ ++QL W + + +G + + VT S+L ++ N T +++
Sbjct 204 NKTSTSLQLRWMDISSWLRDG-LRFFVVTAKSSYSNLTVKGLFSSNTTFAEISGLDPYMA 262
Query 396 YLATLTVRNLVGKS-DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT-PRESVKKY 453
Y ++ + G + VL ++ + + V+W P++
Sbjct 263 YDVSVVAVDGDGSQFKSTVLQARTDEWVPSRAPSVFVTSVTSTSVTVQWNPLPQQYHNGR 322
Query 454 ILEWCVLSDK---APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI 510
+L + V K +P D NL + Y + V+ + G G +
Sbjct 323 LLGYRVFIRKTANSPFPLDESNVAVYNTSWVTLNNLKPGQPYEVNVSAFTSKGDGPRSTH 382
Query 511 KAYL 514
Sbjct 383 YIVT 386
Score = 51.4 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 41/278 (15%), Positives = 83/278 (30%), Gaps = 24/278 (9%)
Query 49 VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTAS---SVTFTDIASLNIQLTCNI 105
++ + + + + V+ + I + N T++ +TF + ++ IQ++
Sbjct 114 IISIEEVQFAYCRGYIKVFDGSGAQIFTRRGCNENHTSNTFLEITFQESQNVTIQVSLE- 172
Query 106 LTFGQLEQNVYGITIISGLPPEK---PK-NLSCIVNEGKKMRCEW----DGGRETHLETN 157
+G I+ G P N S ++ W R+
Sbjct 173 ---NNQSYARFGYGILEGGLESALLLPGWNASLENKTSTSLQLRWMDISSWLRDGLRFFV 229
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKV-TSDHINFDP 216
T KS ++ + T + ++ +V V A + G S +
Sbjct 230 VTAKSSYSNLTVKGLFSSNTTFAEISGLDP---YMAYDVSVVAVDGDGSQFKSTVLQART 286
Query 217 VYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK--SVIILKYNIQYRTKDASTWSQIPP 274
V P + ++ W + + +L Y + R S +
Sbjct 287 DEWVPSRAPSVFVTSVTSTSVTV---QWNPLPQQYHNGRLLGYRVFIRKTANSPFPLDES 343
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
S T+ +LKP Y + G G S
Sbjct 344 NVAVYNTSWVTLNNLKPGQPYEVNVSAFTSKGDGPRST 381
>sp|P31785|IL2RG_HUMAN Cytokine receptor common subunit gamma
OS=Homo sapiens OX=9606 GN=IL2RG PE=1 SV=1
Length=369
Score = 83.8 bits (205), Expect = 1e-15, Method: Composition-based stats.
Identities = 42/198 (21%), Positives = 73/198 (37%), Gaps = 21/198 (11%)
Query 131 NLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA------THKFADCKAKRDTPTSCTV 184
+ C V + M C W+ E TN TL + K + + + C +
Sbjct 59 EVQCFVFNVEYMNCTWNSSSEPQ-PTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQL 117
Query 185 DYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
++ + V ++ + + + + V P P NL++ E S L+L
Sbjct 118 QKKEIHLYQTFVVQLQDPREPRRQATQMLKLQNL--VIPWAPENLTLHKLSE--SQLELN 173
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
W N + L++ +QYRT W E + R F++ + Y FR+R
Sbjct 174 WNNRFLNH--CLEHLVQYRT----DWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRF 227
Query 304 EDGKG---YWSDWSEEAS 318
G +WS+WS
Sbjct 228 NPLCGSAQHWSEWSHPIH 245
Score = 38.3 bits (87), Expect = 0.33, Method: Composition-based stats.
Identities = 21/143 (15%), Positives = 49/143 (34%), Gaps = 10/143 (7%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI-IGNETAVNVDSSHTEY 577
P + K+ +++ L W+ N + + + YRT + T +VD H +
Sbjct 154 PWAPENLTLHKLSESQLELNWNN---RFLNHCLEH-LVQYRTDWDHSWTEQSVDYRHK-F 208
Query 578 TLSSLTSDTLYMVRMAA-YTDEGGKDGPEFTFTTPK---FAQGEIEAIVVPVCLAFLLTT 633
+L S+ Y R+ + + G ++ P + + + +
Sbjct 209 SLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVG 268
Query 634 LLGVLFCFNKRDLIKKHIWPNVP 656
+G++ + P +P
Sbjct 269 SMGLIISLLCVYFWLERTMPRIP 291
>sp|P40321|IL2RG_CANLF Cytokine receptor common subunit gamma
OS=Canis lupus familiaris OX=9615 GN=IL2RG PE=2 SV=1
Length=373
Score = 83.4 bits (204), Expect = 1e-15, Method: Composition-based stats.
Identities = 46/198 (23%), Positives = 79/198 (40%), Gaps = 21/198 (11%)
Query 131 NLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATH---KFADCKA---KRDTPTSCTV 184
+ C V + M C W+ E TN TL + K +C R+ C +
Sbjct 59 EVQCFVFNVEYMNCTWNSSSEPR-PTNLTLHYWYKNSNDDKVQECGHYLFSREVTAGCWL 117
Query 185 DYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
++ + V + + ++ + + V P P NL++ N E S L+L+
Sbjct 118 QKEEIHLYETFVVQLRDPREPRRQSTQKLKLQNL--VIPWAPENLTLHNLSE--SQLELS 173
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
W+N + L++ +QYR S W + E + R+SF++ + Y FR+R
Sbjct 174 WSNRHLDH--CLEHVVQYR----SDWDRSWTEQSVDHRNSFSLPSVDGQKFYTFRVRSRY 227
Query 304 EDGKGY---WSDWSEEAS 318
G WS+WS
Sbjct 228 NPLCGSAQRWSEWSHPIH 245
Score = 39.1 bits (89), Expect = 0.19, Method: Composition-based stats.
Identities = 23/148 (16%), Positives = 53/148 (36%), Gaps = 21/148 (14%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
P + + +++ L W +D + Y + + T +VD ++
Sbjct 154 PWAPENLTLHNLSESQLELSWSNRHLDHCLEHVVQYRSDW---DRSWTEQSVD-HRNSFS 209
Query 579 LSSLTSDTLYMVRMAAYT----------DEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLA 628
L S+ Y R+ + E + T+ + EA+++P+
Sbjct 210 LPSVDGQKFYTFRVRSRYNPLCGSAQRWSEWSHPIHWGSNTSKENPLFASEAVLIPLGSM 269
Query 629 FLLTTLLGVLFCFNKRDLIKKHIWPNVP 656
L+ +L+ V + +++ I P +P
Sbjct 270 GLIISLICVYY------WLERSI-PRIP 290
>sp|O15394|NCAM2_HUMAN Neural cell adhesion molecule 2 OS=Homo
sapiens OX=9606 GN=NCAM2 PE=1 SV=2
Length=837
Score = 85.3 bits (209), Expect = 2e-15, Method: Composition-based stats.
Identities = 46/267 (17%), Positives = 78/267 (29%), Gaps = 20/267 (7%)
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
ND T N +G + D ++ + + + V + P
Sbjct 468 NDFGRYNCTATNHIGT-RFQEYILALADVPSSPYGVKIIELSQTTA-KVSFNKPDSHGGV 525
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
I + V + V + NL + Y I V V G G I+
Sbjct 526 PIHHYQVDVKEVASEIWKIVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGKGQGDYSKIEI 585
Query 513 YLKQAPP---SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET--A 567
+ Q P P++ + L D I Y + YR+ +
Sbjct 586 F--QTLPVREPSPPSIHGQPSSGKSFKLS--ITKQDDGGAPILEYIVKYRSKDKEDQWLE 641
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK---------FAQGEI 618
V + L L Y V++ A G + + F+ P F +
Sbjct 642 KKVQGNKDHIILEHLQWTMGYEVQITAANRLGYSEPTVYEFSMPPKPNIIKDTLFNGLGL 701
Query 619 EAIVVPVCLAFLLTTLLGVLFCFNKRD 645
A++ A LL ++ + CF R
Sbjct 702 GAVIGLGVAALLLILVVTDVSCFFIRQ 728
Score = 74.1 bits (180), Expect = 3e-12, Method: Composition-based stats.
Identities = 55/304 (18%), Positives = 94/304 (31%), Gaps = 52/304 (17%)
Query 129 PKNLSCIVNEGKKMRCEWDGGR-------ETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
P N+SC V W + T+L+T T + A +
Sbjct 417 PINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYST--GRKMILEIAPTSDNDFGRYN 474
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
C A N +G T + V +P V E + K
Sbjct 475 C----------------TATNHIG--TRFQEYILALADVPSSP---YGVKIIELSQTTAK 513
Query 242 LTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
+++ P S V I Y + + + W + ++ + +L+P T Y R+
Sbjct 514 VSFNKPDSHGGVPIHHYQVDVKEVASEIWKIVRSHGV---QTMVVLNNLEPNTTYEIRVA 570
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
+ G+G D+S+ T R PS PS + ++ + + +
Sbjct 571 AVNGKGQG---DYSKIEIFQTLPVREPSPPSI--HGQPSSGKSFK-LSIT-----KQDDG 619
Query 361 G-KILDYEVTLTRWKSHLQ----NYTVNATKLTVNLTND--RYLATLTVRNLVGKSDAAV 413
G IL+Y V Q N + + Y +T N +G S+ V
Sbjct 620 GAPILEYIVKYRSKDKEDQWLEKKVQGNKDHIILEHLQWTMGYEVQITAANRLGYSEPTV 679
Query 414 LTIP 417
Sbjct 680 YEFS 683
Score = 69.9 bits (169), Expect = 7e-11, Method: Composition-based stats.
Identities = 39/276 (14%), Positives = 81/276 (29%), Gaps = 19/276 (7%)
Query 41 HSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINR-TASSVTFTDIASLNI 99
+ C +K I W+ + +P + T + + +IA +
Sbjct 415 GNPINISCDVKSN-------PPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSD 467
Query 100 QLTC--NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD-GGRETHLET 156
N + + P P + I + ++ +
Sbjct 468 NDFGRYNCTATNHIGTRFQEYILALADVPSSPYGVKIIELSQTTAKVSFNKPDSHGGVPI 527
Query 157 N-FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINF 214
+ + + + + T ++ + E+ V A N G+ S F
Sbjct 528 HHYQVDVKEVASEIWKIVRSHGVQTMVVLN-NLEPNTTYEIRVAAVNGKGQGDYSKIEIF 586
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
+ +P+PP S+ KL+ T IL+Y ++YR+KD Q
Sbjct 587 QTLPVREPSPP---SIHGQPSSGKSFKLSITKQDDGGAPILEYIVKYRSKDKED--QWLE 641
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
+ + ++ L+ Y +I G
Sbjct 642 KKVQGNKDHIILEHLQWTMGYEVQITAANRLGYSEP 677
>sp|Q4W815|EPOR_XENLA Erythropoietin receptor OS=Xenopus laevis
OX=8355 GN=epor PE=2 SV=1
Length=525
Score = 84.1 bits (206), Expect = 2e-15, Method: Composition-based stats.
Identities = 37/200 (19%), Positives = 76/200 (38%), Gaps = 10/200 (5%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL--KSEWATHKFADCKAKRDTPTSCT 183
PE+ +N C + C W+G R + +++ + +W +
Sbjct 50 PEEYQNPHCFTRDLNDFICFWEGERRKNASFSYSEDDQIKWCQLRTEVASNNTWWYICEF 109
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
V F I + + T+ I + + V NPP N++V ++ L ++
Sbjct 110 PVTDVVLFAGITISAYPCHKC--QTAREIYINEL--VLLNPPLNVTVKEKQD-PRGLLIS 164
Query 244 WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
W P + + I+Y+ ++ + + + + + + D+ P Y +RC
Sbjct 165 WKPPHFQKNHDINNEIKYQVNYSTPGADMQTVEVEAGNTEIFLTDIVPAA-YTVTVRCKA 223
Query 304 E--DGKGYWSDWSEEASGIT 321
+ GYWSDW+ + T
Sbjct 224 DGVSYNGYWSDWTAPITIAT 243
Score = 59.9 bits (143), Expect = 7e-08, Method: Composition-based stats.
Identities = 35/184 (19%), Positives = 65/184 (35%), Gaps = 12/184 (7%)
Query 494 ITVTPVYADGPGSPESIKAYLKQAPPSKGP-TVRTKK-VGKNEAVLEWDQLPVDVQ---N 548
IT++ + I Y+ + P V K+ ++ W N
Sbjct 120 ITISAYPCHKCQTAREI--YINELVLLNPPLNVTVKEKQDPRGLLISWKPPHFQKNHDIN 177
Query 549 GFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
I+ Y + Y T + V V++ +TE L+ + Y V + D +G +
Sbjct 178 NEIK-YQVNYSTPGADMQTVEVEAGNTEIFLTDIVPAA-YTVTVRCKADGVSYNGYWSDW 235
Query 609 TTPKFAQGEIEAIVV---PVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQ 665
T P I+ ++ + + L +GV +K +WP VP P +
Sbjct 236 TAPITIATIIDLRLLLLLSIAIFVALIAGVGVYIFMRHGMYLKHKVWPQVPTPENNFQGL 295
Query 666 WSPH 669
++ H
Sbjct 296 FTTH 299
>sp|Q95118|IL2RG_BOVIN Cytokine receptor common subunit gamma
OS=Bos taurus OX=9913 GN=IL2RG PE=2 SV=1
Length=379
Score = 82.6 bits (202), Expect = 2e-15, Method: Composition-based stats.
Identities = 44/199 (22%), Positives = 73/199 (37%), Gaps = 22/199 (11%)
Query 131 NLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWAT----HKFADCKA---KRDTPTSCT 183
+ C V + M C W+ E N TL + K +C + C
Sbjct 65 KVQCFVFNVEYMNCTWNSSSEPQ-PNNLTLHYGYRNFNGDDKLQECGHYLFSEGITSGCW 123
Query 184 VDYSTV-YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
+ + V ++ K + + V P P NL++ N E L+L
Sbjct 124 FGKKEIRLYETFVVQLQDPREHRKQPKQMLKLQDL--VIPWAPENLTLRNLSEF--QLEL 179
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
+W+N + L++ +QYR+ +W E + R SF++ + Y FR+R
Sbjct 180 SWSNRYLDH--CLEHLVQYRSDRDRSW----TEQSVDHRHSFSLPSVDAQKLYTFRVRSR 233
Query 303 KEDGKG---YWSDWSEEAS 318
G +WSDWS
Sbjct 234 YNPLCGSAQHWSDWSYPIH 252
Score = 37.1 bits (84), Expect = 0.67, Method: Composition-based stats.
Identities = 21/154 (14%), Positives = 50/154 (32%), Gaps = 26/154 (17%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
P + + + + + L W +D + + + + T +VD H ++
Sbjct 161 PWAPENLTLRNLSEFQLELSWSNRYLDH---CLEHLVQYRSDRDRSWTEQSVDHRH-SFS 216
Query 579 LSSLTSDTLYMVRMAAYT-----DEG-----------GKDGPEFTFTTPKFAQGEIEAIV 622
L S+ + LY R+ + G + + P+ V
Sbjct 217 LPSVDAQKLYTFRVRSRYNPLCGSAQHWSDWSYPIHWGSNTSKENIENPENPSLFALEAV 276
Query 623 VPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVP 656
+ + L L ++C +++ + P +P
Sbjct 277 LIPLGSMGLIVSLICVYC-----WLERTM-PRIP 304
>sp|P79194|GHR_MACMU Growth hormone receptor OS=Macaca mulatta
OX=9544 GN=GHR PE=2 SV=1
Length=638
Score = 84.1 bits (206), Expect = 2e-15, Method: Composition-based stats.
Identities = 38/204 (19%), Positives = 77/204 (38%), Gaps = 27/204 (13%)
Query 128 KPKNLSCIVNEGKKMRCEW-----DGGRETH-LETNFTLKS-EWATHKFADCKAK-RDTP 179
+PK C E + C W G + ++ +T ++ + T ++ +C
Sbjct 50 EPKFTKCRSPERETFSCHWTDAVHHGSKSLGPIQLFYTRRNIQGQTQEWKECPDYVSAGE 109
Query 180 TSCTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
SC + S ++ + + + T D F V+P+PP L+ +
Sbjct 110 NSCYFNSSFTSVWIPYCIKLTSNGD----TVDGKCFSVDEIVQPDPPIALNWTLLNVSLT 165
Query 239 ILK----LTWTNPSIKSV----IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + W P + ++L+Y +QY+ + + W + P +S V LK
Sbjct 166 GIHADILVRWEAPPNADIQKGWMVLEYELQYKEVNETKWKMMDPIL----STSVPVYSLK 221
Query 291 PFTEYVFRIRCMKEDG--KGYWSD 312
EY +R + + G +S+
Sbjct 222 VDKEYEVLVRSKRRNSRNYGEFSE 245
Score = 59.1 bits (141), Expect = 1e-07, Method: Composition-based stats.
Identities = 68/382 (18%), Positives = 126/382 (33%), Gaps = 56/382 (15%)
Query 447 RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
R +++ EW D + + + ++ Y I +T G
Sbjct 88 RRNIQGQTQEWKECPDYVSAGENSCYFNSSFTSVWI--------PYCIKLTSNGDTVDGK 139
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKN----EAVLEWDQLP-VDVQNG-FIRNYTIFYRT 560
S+ ++ PP V + ++ W+ P D+Q G + Y + Y+
Sbjct 140 CFSVDEIVQPDPPIAL-NWTLLNVSLTGIHADILVRWEAPPNADIQKGWMVLEYELQYKE 198
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA--YTDEGGKDGPE-FTFTTPKFAQGE 617
+ + + T + SL D Y V + + + E T P+ Q
Sbjct 199 VNETKWKMMDPILSTSVPVYSLKVDKEYEVLVRSKRRNSRNYGEFSEVLYVTLPQMNQFT 258
Query 618 IEA-----IVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPP 672
E ++ + T++ +F F+K+ IK I P VP P I +P
Sbjct 259 CEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPPVPVP---KIKGINPDLLK 315
Query 673 RHNFNS-----------KDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINT 721
K + +SD ++ + ++I+ D+K D L +K ++
Sbjct 316 EGKLEEVNAILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKNEGSDTDRLLSSDHQKSHS 375
Query 722 EGHSSGIGGSSCMSSSRPSISSSDENESS--QNTSSTVQYSTVVH--------------S 765
G S S P I +D N ++ + TS Q + S
Sbjct 376 NLGVKD-GDSGRTSCYEPDILETDFNANNIHEGTSEVAQPQRLKGEADLLCLDQKNQNKS 434
Query 766 GYRHQVPSVQV--FSRSESTQP 785
Y P+ Q ++E +P
Sbjct 435 PYHDACPATQQPSVIQAEKNKP 456
>sp|B3DK56|PTPRU_DANRE Receptor-type tyrosine-protein phosphatase
U OS=Danio rerio OX=7955 GN=ptpru PE=2 SV=1
Length=1444
Score = 84.5 bits (207), Expect = 3e-15, Method: Composition-based stats.
Identities = 49/354 (14%), Positives = 103/354 (29%), Gaps = 41/354 (12%)
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
RC+ + +G E P P T ++
Sbjct 259 RCVTQSSRGSGVSNFAELIVKVPPS-PIAPPQLLRAGSTYLIIQLNTNSIL--------G 309
Query 360 NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR---YLATLTVRNLVGKSDAAVLTI 416
+G I+ E+ + D Y ++ +
Sbjct 310 DGPIIRREIEYRASLAPWSEILGVNMVTYKLWHLDPDTEYHISVLLTRPGEGGTGPPGPP 369
Query 417 PACDFQATHPVMDLKAFPKDNM----LWVEWTTPRESVKK---YIL----EWCVLSDKAP 465
+ P+ L+ + L ++W P ++ + Y + +
Sbjct 370 LISRTKCAEPMRALRGLRASEIQSRQLTLQWEVPAFNLTRCHTYSVSLCYRYTTAGGGGG 429
Query 466 CITDWQQ--EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK-G 522
T ++ + +L I + +G + + ++ P
Sbjct 430 HNTTVRECLAVEHNTSRFTLRDLPPFHTIQIRLALANTEGKKEGKEVMFQTEEDIPGGIA 489
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS---------S 573
P T ++ L+W++ NG I Y I Y++I ++ +NV +
Sbjct 490 PESLTFTPLEDMIFLKWEE--PVEPNGLITQYEISYQSIESSDPGINVPGPRRTVSKLKN 547
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT----PKFAQGEIEAIVV 623
T + S+L T Y++ + A T +G TT P F G++ + +
Sbjct 548 ETYHMFSNLHPGTTYLISVRARTAKGFGQTALTEITTNISAPTFDYGDMPSPLS 601
Score = 78.7 bits (192), Expect = 2e-13, Method: Composition-based stats.
Identities = 120/756 (16%), Positives = 223/756 (29%), Gaps = 104/756 (14%)
Query 38 VQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIP--KEQYTIINRTASSVTFTDIA 95
V N T CV + +++ + N ++ NR A S D+
Sbjct 196 VNAGQNATFQCVAAGR----PSEAEKFLLERHNGEVSSGGSVKHLGRNRFAVSFQLEDVQ 251
Query 96 SLNIQLT-CNILTFGQLEQNVYGITIISGLPPEK---PKNLSCIVNEGKKMRCEWDGGRE 151
L C + + + +I +PP P+ L + + +
Sbjct 252 KPEQDLYRCVTQSSRGSGVSNF-AELIVKVPPSPIAPPQLL---RAGSTYLIIQLNTNSI 307
Query 152 THLETNFTLKSEWATHKFADCK---AKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
+ E+ + T +D T Y +++ + G+
Sbjct 308 LGDGPIIRREIEYRASLAPWSEILGVNMVTYKLWHLDPDTEYHISVLL-----TRPGEGG 362
Query 209 SDHINFDPVYKVKPNPPHN--LSVINSEELSSILKLTWTNPSIKSVIILKYNI----QYR 262
+ + + K P + SE S L L W P+ Y++ +Y
Sbjct 363 TGPPGPPLISRTKCAEPMRALRGLRASEIQSRQLTLQWEVPAFNLTRCHTYSVSLCYRYT 422
Query 263 TKDASTWSQIPPED---TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
T + S FT++DL PF + +IR + +G +E
Sbjct 423 TAGGGGGHNTTVRECLAVEHNTSRFTLRDLPPF--HTIQIRLALANTEGK--KEGKEVMF 478
Query 320 ITYEDRPSK-APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
T ED P AP + T + L W+ P E NG I YE++ +S
Sbjct 479 QTEEDIPGGIAPE-----SLTFTPLEDMIFLKWEE--PVEPNGLITQYEISYQSIESSDP 531
Query 379 NYTVNATKLTVNLTNDR-------------YLATLTVRNLVGKSDAAVLTIPACDFQATH 425
V + TV+ + YL ++ R G A+ I T
Sbjct 532 GINVPGPRRTVSKLKNETYHMFSNLHPGTTYLISVRARTAKGFGQTALTEITTNISAPTF 591
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
D+ + + + + + ++ +Q ++
Sbjct 592 DYGDMPSPLSETENTIT------------VLLRPAQGRGAPVSTYQVVVEEEAGRKVKRE 639
Query 486 LAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN-EAVLEWDQLPV 544
L C+ I + A G+P Y + PPS VG N W+
Sbjct 640 LGIQDCFPIPTSHGEAQARGAPH---YYTAELPPSSLSEATPFTVGDNHTYNGYWNSPLD 696
Query 545 DVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
+N Y ++++ + ++ +R+ A
Sbjct 697 PRKN-----YLVYFQAMSNFRGETRINC-----------------IRI-ARKAACKDHQR 733
Query 605 EFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIA 664
T G I + + +L ++ RD +P P
Sbjct 734 ALEVTQRSEEMGLILGVCAGGLVVLILLLGAIIIIIKKGRDYYSYSYYPRKPGNMN---- 789
Query 665 QWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGH 724
+P T + N M + +FTD S ++ + F D + + +
Sbjct 790 -KTPITYRQEKSNMMGSM--ERSFTDQSTLQEDERMALSFM-DTHTCSTRSDPRSSMNES 845
Query 725 SSGIGGSSCMSSSRP-SISSSDENESSQNTSSTVQY 759
SS +GGS R S + + + + +Q+
Sbjct 846 SSLLGGSPRRQCGRKGSPYHTGQLHPAVRVADLLQH 881
>sp|Q5JZY3|EPHAA_HUMAN Ephrin type-A receptor 10 OS=Homo sapiens
OX=9606 GN=EPHA10 PE=1 SV=2
Length=1008
Score = 84.1 bits (206), Expect = 3e-15, Method: Composition-based stats.
Identities = 39/269 (14%), Positives = 80/269 (30%), Gaps = 32/269 (12%)
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL-------- 460
S + + + +L + W P +S + + + +L
Sbjct 325 SPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREG 384
Query 461 -----SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA-DGPGSPE-----S 509
P + ++ G R +L Y + V + GP +
Sbjct 385 PAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQ 444
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEW-DQLPVDVQNGFIRNYTI-FYRTIIGNETA 567
+ P + +R +V L W + +P Y I +Y +T
Sbjct 445 VTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTY 504
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG----PEFTFTTPKFAQG------- 616
V + T+++L T Y+ ++ A + + P T A
Sbjct 505 SMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLGEAASGSRDQSP 564
Query 617 EIEAIVVPVCLAFLLTTLLGVLFCFNKRD 645
I VV + +L +++ VL + +
Sbjct 565 AIVVTVVTISALLVLGSVMSVLAIWRRPC 593
Score = 79.9 bits (195), Expect = 8e-14, Method: Composition-based stats.
Identities = 38/246 (15%), Positives = 70/246 (28%), Gaps = 24/246 (10%)
Query 125 PPEKPKNLS-CIVNEGKKMRCEWDGGRETH--LETNFTLKSEWATHK-----FADCKAKR 176
PP P++L + +R W ++ + ++L + C +
Sbjct 337 PPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRV 396
Query 177 DT---PTSCTVDYSTVYFVN----IEVWVEAENALG--KVTSDHINFDPVYKVKPNPPHN 227
+T+ + V V A N + + P P
Sbjct 397 AFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWE 456
Query 228 L-SVINSEELSSILKLTWTNP---SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
+ + L+W P +Y I+Y K S+ + +
Sbjct 457 EDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYEKG---QSEQTYSMVKTGAPT 513
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
TV +LKP T YVF+IR ++ T + S + I +
Sbjct 514 VTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTLGEAASGSRDQSPAIVVTVVTI 573
Query 344 YRTVQL 349
+ L
Sbjct 574 SALLVL 579
Score = 56.8 bits (135), Expect = 9e-07, Method: Composition-based stats.
Identities = 37/266 (14%), Positives = 74/266 (28%), Gaps = 49/266 (18%)
Query 315 EEASGITYEDRPS----KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI-LDYEVT 369
+++ + D PS + PS + S ++ ++L W LPP ++ G+ + Y +
Sbjct 319 QDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRW--LPPADSGGRSDVTYSLL 376
Query 370 LTRWKSHLQNYTVN------------------ATKLTVNLTNDRYLATLTVRNLVGKSDA 411
R A L RY + N V A
Sbjct 377 CLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAA 436
Query 412 AV------LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV------KKYILEWCV 459
A +T+ + + + + W P + +Y + +
Sbjct 437 AAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYE 496
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK-----AYL 514
+ + TV T NL + Y+ + +S L
Sbjct 497 KGQSEQTYSMVKTGAPTVTVT----NLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTL 552
Query 515 KQAPPSKG---PTVRTKKVGKNEAVL 537
+A P + V + ++
Sbjct 553 GEAASGSRDQSPAIVVTVVTISALLV 578
>sp|Q02763|TIE2_HUMAN Angiopoietin-1 receptor OS=Homo sapiens
OX=9606 GN=TEK PE=1 SV=2
Length=1124
Score = 84.1 bits (206), Expect = 4e-15, Method: Composition-based stats.
Identities = 51/298 (17%), Positives = 92/298 (31%), Gaps = 21/298 (7%)
Query 356 PFEANGKILDYEVTLTRWKSH--LQNYTVNATKLTVNLTNDRYLATLTV----RNLVGKS 409
P+ +G I ++ + Q+ V +T+N R L V R G+
Sbjct 469 PYFGDGPIKSKKLLYKPVNHYEAWQHIQVTNEIVTLNYLEPRTEYELCVQLVRRGEGGEG 528
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWTT--PRESVKKYILEWCVLSDKAPC 466
+ P L PK L + W P Y+ K
Sbjct 529 HPGPVRRFTTASIGLPPPRGLNLLPKSQTTLNLTWQPIFPSSEDDFYVEVERRSVQK--S 586
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVT-PVYADGPGSPESIKAYLKQAPPSKGPTV 525
+ G + L NL + Y++ A G S + L P + +
Sbjct 587 DQQNIKVPGNLTSVLL-NNLHPREQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENI 645
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSD 585
+ + + AV+ W L + Y + + + +++ T+Y L L +
Sbjct 646 KISNITHSSAVISWTILDGYSISSITIRYKVQGKNEDQHVDVKIKNATITQYQLKGLEPE 705
Query 586 TLYMVRMAAYTDEGGKDG--PEFTFTTPK------FAQGEIEAIVVPVCLAFLLTTLL 635
T Y V + A + G + T P+ G++ I + T+L
Sbjct 706 TAYQVDIFAENNIGSSNPAFSHELVTLPESQAPADLGGGKMLLIAILGSAGMTCLTVL 763
Score = 79.9 bits (195), Expect = 7e-14, Method: Composition-based stats.
Identities = 59/363 (16%), Positives = 115/363 (32%), Gaps = 25/363 (7%)
Query 154 LETN--FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDH 211
L TN TL T D + + + VWV + N + +
Sbjct 377 LPTNEEMTLVKPDGTVLHPKDFNHTDHFSVAIFTIHRILPPDSGVWVCSVNTVAGMVEKP 436
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA-STWS 270
F+ KV P P + +VI++ +++ ++ + P I + Y+ + W
Sbjct 437 --FNISVKVLPKPLNAPNVIDTGHNFAVINIS-SEPYFGDGPIKSKKLLYKPVNHYEAWQ 493
Query 271 QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
I T T+ L+P TEY ++ ++ G T P
Sbjct 494 HIQV-----TNEIVTLNYLEPRTEYELCVQLVRRGEGGEGHP--GPVRRFTTASIGLPPP 546
Query 331 SFWYKIDPSHTQGYRTVQLVWKTL-PPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV 389
+ S T T+ L W+ + P E + + ++ + N T + +
Sbjct 547 RGLNLLPKSQT----TLNLTWQPIFPSSEDDFYVEVERRSVQKSDQQNIKVPGNLTSVLL 602
Query 390 NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM----DLKAFPKDNMLWVEWT- 444
N + R + R + A P + + + + WT
Sbjct 603 NNLHPREQYVVRARVNTKAQGEWSEDLTAWTLSDILPPQPENIKISNITHSSAV-ISWTI 661
Query 445 TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
S+ + + V D + ++ T+ + L+G L Y + + G
Sbjct 662 LDGYSISSITIRYKVQGKNEDQHVDVKIKNATITQYQLKG-LEPETAYQVDIFAENNIGS 720
Query 505 GSP 507
+P
Sbjct 721 SNP 723
Score = 79.5 bits (194), Expect = 9e-14, Method: Composition-based stats.
Identities = 42/218 (19%), Positives = 73/218 (33%), Gaps = 18/218 (8%)
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
F P PP L+++ + + L LTW S ++ R+ S I
Sbjct 536 FTTASIGLP-PPRGLNLLPKSQ--TTLNLTWQPIFPSSEDDFYVEVERRSVQKSDQQNIK 592
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
+S + +L P +YV R R + +WSE+ + T D P
Sbjct 593 ---VPGNLTSVLLNNLHPREQYVVRARVNTKAQ----GEWSEDLTAWTLSDILPPQPENI 645
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL-- 391
+ +H+ + + W L + + + Y+V H+ NAT L
Sbjct 646 KISNITHS----SAVISWTILDGYSISSITIRYKVQGKNEDQHVDVKIKNATITQYQLKG 701
Query 392 --TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
Y + N +G S+ A ++ P
Sbjct 702 LEPETAYQVDIFAENNIGSSNPAFSHELVTLPESQAPA 739
Score = 74.9 bits (182), Expect = 3e-12, Method: Composition-based stats.
Identities = 46/311 (15%), Positives = 94/311 (30%), Gaps = 42/311 (14%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
V+ NF + + E + + +++K P Y + I
Sbjct 453 VIDTGHNFAVINISSEPYFGDGPIKSKKLLYK------PVNHYE---------AWQHIQV 497
Query 97 LNIQLTCNILTFGQLEQNVYG------------------ITIISGLPPEKPKNLSCIVNE 138
N +T N L + T GLPP P+ L+ +
Sbjct 498 TNEIVTLNYLEPRTEYELCVQLVRRGEGGEGHPGPVRRFTTASIGLPP--PRGLNLLPKS 555
Query 139 GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWV 198
+ W + + + + K K + + + V
Sbjct 556 QTTLNLTWQPIFPSSEDDFYVEVERRSVQKSDQQNIKVPGNLTSVLLNNLHPREQYVVRA 615
Query 199 EAEN-ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY 257
A G+ + D + + P P N+ + N S+++ +WT + I
Sbjct 616 RVNTKAQGEWSEDLTAWTLSDILPPQ-PENIKISNITHSSAVI--SWT--ILDGYSISSI 670
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
I+Y+ + + + + +T + + ++ L+P T Y I G +S E
Sbjct 671 TIRYKVQGKNEDQHVDVKIKNATITQYQLKGLEPETAYQVDIFAENNIGSSNP-AFSHEL 729
Query 318 SGITYEDRPSK 328
+ P+
Sbjct 730 VTLPESQAPAD 740
>sp|A5HJM1|IL7RA_CALJA Interleukin-7 receptor subunit alpha OS=Callithrix
jacchus OX=9483 GN=IL7R PE=2 SV=1
Length=459
Score = 82.2 bits (201), Expect = 6e-15, Method: Composition-based stats.
Identities = 33/122 (27%), Positives = 59/122 (48%), Gaps = 6/122 (5%)
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI-LKLTWTNPSIKSVIILKYNIQYR- 262
G+ + N + VKP P +LSVI E + + ++ K V +L +++ YR
Sbjct 112 GEKSLTCKNVNVATIVKPEAPFDLSVIYREGANDFLVTFNTSHLQKKYVKVLMHDVAYRH 171
Query 263 TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK-EDGKGYWSDWSEEASGIT 321
KD + W + + +ST+ + + L+P Y ++R + + KG+WS+WS T
Sbjct 172 EKDENNWMHV---NLSSTKLTLLQRKLQPKATYEIKVRSIPGDYFKGFWSEWSPSYYFRT 228
Query 322 YE 323
E
Sbjct 229 PE 230
Score = 41.0 bits (94), Expect = 0.052, Method: Composition-based stats.
Identities = 34/192 (18%), Positives = 74/192 (39%), Gaps = 27/192 (14%)
Query 556 IFYRTIIGNETAVNVDSSHTEYTL--SSLTSDTLYMVRMAA-----YTDEGGKDGPEFTF 608
+ YR ++V+ S T+ TL L Y +++ + + + P + F
Sbjct 167 VAYRHEKDENNWMHVNLSSTKLTLLQRKLQPKATYEIKVRSIPGDYFKGFWSEWSPSYYF 226
Query 609 TTPKF----AQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPD------- 657
TP+ + + + + + L+ + K+ IK IWP++PD
Sbjct 227 RTPEINNHSGETNPTLLTISILSVLSVVLLVILACVLWKK-RIKPIIWPSLPDHKKTLEH 285
Query 658 ----PSKSHIAQWSPHTPPRHNFNSKDQMYS----DGNFTDVSVVEIEANDKKPFPEDLK 709
PSK+ I ++P + + D + + +G D ++E ++ + D++
Sbjct 286 LCKKPSKNLIVSFNPESFLDCQIHRVDDIQARDEVEGFLQDTVPPQLEESETQRPGGDVQ 345
Query 710 SLDLFKKEKINT 721
S + + T
Sbjct 346 SPSWPSENVVTT 357
>sp|P40238|TPOR_HUMAN Thrombopoietin receptor OS=Homo sapiens
OX=9606 GN=MPL PE=1 SV=1
Length=635
Score = 82.2 bits (201), Expect = 9e-15, Method: Composition-based stats.
Identities = 77/542 (14%), Positives = 151/542 (28%), Gaps = 61/542 (11%)
Query 132 LSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKR------DTPTSCTVD 185
L C + + C WD E + L + K C T C
Sbjct 38 LKCFSRTFEDLTCFWD-EEEAAPSGTYQLLYAYPREKPRACPLSSQSMPHFGTRYVCQFP 96
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ + + +N T P PP + + L+++W
Sbjct 97 DQEEVRLFFPLHLWVKNVFLNQTRTQRVLFVDSVGLPAPPSIIKAMG-GSQPGELQISWE 155
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P+ + L+Y ++Y +D P+++ + TE C
Sbjct 156 EPAPEISDFLRYELRYGPRD--------PKNSTGPTVIQLI-----ATE-----TCCPAL 197
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
+ S + P P+ ++ P T R L + I
Sbjct 198 QR--------PHSASALDQSPCAQPTMPWQDGPKQTSPSREAS----ALTAEGGSCLISG 245
Query 366 YEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATH 425
L S+ +++ + + +TV +L G + A L D +
Sbjct 246 ----LQPGNSYWLQLRSEPDGISLGGSWGSWSLPVTV-DLPGDAVALGLQCFTLDLKNVT 300
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+ + +Y + W ++ Q + R +
Sbjct 301 CQWQQQDHASSQGFFYHSRARCCPRDRYPI-WENCEEEEKTNPGLQTPQFSRCHFKSRND 359
Query 486 LAESKCYLITVTPVYADGP-GSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
+T P GSP ++ QA P + +++ LEW
Sbjct 360 SIIHILVEVTTAPGTVHSYLGSP----FWIHQAVRLPTPNLHWREISSGHLELEWQH--P 413
Query 545 DVQNGFIRNYTIFYR-TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
Y + Y + + TL L + Y +++ A + G
Sbjct 414 SSWAAQETCYQLRYTGEGHQDWKVLEPPLGARGGTLE-LRPRSRYRLQLRARLNGPTYQG 472
Query 604 PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDL--------IKKHIWPNV 655
P +++ P + E + + A L L + ++ +WP++
Sbjct 473 PWSSWSDPTRVETATETAWISLVTALHLVLGLSAVLGLLLLRWQFPAHYRRLRHALWPSL 532
Query 656 PD 657
PD
Sbjct 533 PD 534
>sp|O18023|IGDB2_CAEEL Ig-like and fibronectin type-III domain-containing
protein 2 OS=Caenorhabditis elegans OX=6239 GN=igdb-2
PE=1 SV=4
Length=1526
Score = 82.6 bits (202), Expect = 1e-14, Method: Composition-based stats.
Identities = 79/520 (15%), Positives = 147/520 (28%), Gaps = 87/520 (17%)
Query 129 PKNLSCIVNEGKKMRCEW-------DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
P ++ C + C D + + T ++EW K + C A T
Sbjct 479 PDSMKCCTDANVTSFCSSKMCNVAEDPSSFSTITIATTCRAEWP--KVSPCIADGRNHTD 536
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYK---------VKPNPPHNLSVIN 232
C + V +E+ + LG + +N D P+ P N+++
Sbjct 537 CCLKKG-VQHDCLEICSGSTKELGVHSVLCLNLDLQAIYQCIRQGYETHPSAPGNVTI-- 593
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
SE + + + WT P+ + ++ Y + R + + S L P
Sbjct 594 SELTAHSVTVQWTEPNSNAHLVENYTLFIRKNEHGE----AVRTVKNVISPHVELGLDPD 649
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
+EYV ++ +G S S T P+ P +P + R +
Sbjct 650 SEYVLTLQSHSANGT---SLPSTAKLFSTL---PTTRPPLCTIGEPIYMNDGRVMICDAV 703
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
P +++ + + + + S
Sbjct 704 NPCPNGFRCTGAGSDLSYCCPHDGTHSSEEFTSCCKEQKMPESCM----------SSCQY 753
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQ 472
+T+P +E++ ++ D C +
Sbjct 754 NMTLPESC--------------------------KENLNTWVQCASEGHDHLRCCLQEEV 787
Query 473 EDGTVHRTYLRGNLAESKCYLITVTP--VYADGPGSPESIKAYLKQAPPSKGPTVRTKKV 530
TV +++ + + QA P+ V +
Sbjct 788 SKPCQTACM-----HP-----FTVPADECFSE-VSKYRTCFSAAHQALPAAVRNVEVSSI 836
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMV 590
K+ A + W+ L I + + GN +SS + L + Y V
Sbjct 837 SKDSATISWEDL-----EANIIVFRVQLFEKGGNLIK-TENSSADIFRFIDLEPNKDYSV 890
Query 591 RMAAYTDEG-GKDGPEFTFTTPKFAQGEIEAIVVPVCLAF 629
R+ A G G TFTT E + V P L
Sbjct 891 RVTAINFLGEGPPSWNATFTTKPAQIYEGDRPVAPEKLRI 930
Score = 79.5 bits (194), Expect = 1e-13, Method: Composition-based stats.
Identities = 48/290 (17%), Positives = 95/290 (33%), Gaps = 27/290 (9%)
Query 160 LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYK 219
++ H C + + C + V A+ +V+ F ++
Sbjct 769 VQCASEGHDHLRCCLQEEVSKPCQ---TACMHP---FTVPADECFSEVSKYRTCFSAAHQ 822
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
P N+ V + ++W + I+ + +Q K + I E+ S
Sbjct 823 ALPAAVRNVEVSSI--SKDSATISWEDLEAN---IIVFRVQLFEKGG---NLIKTEN--S 872
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
+ F DL+P +Y R+ + G+G S W+ + + P K+ S
Sbjct 873 SADIFRFIDLEPNKDYSVRVTAINFLGEGPPS-WNATFTTKPAQIYEGDRPVAPEKLRIS 931
Query 340 HTQGYRTVQLVWKTLPP---FEANGKILDYEVTL--TRWKSHLQNYTVNATKLT-VNLTN 393
G R V + W + E K ++Y + T S N T + +L
Sbjct 932 WNSGPR-VNVTWDPVSVRRNAEVVTKPIEYTIYYLDTEQSSTWTTLRTNQTWVVMRDLRK 990
Query 394 DR-YLATLTVR--NLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW 440
D Y +T + N +S + + + D + + ++
Sbjct 991 DALYYVYVTAKEDNRTSRSSSIITILAQKDSPGLPEPTIVIEPDHKDGVF 1040
Score = 75.7 bits (184), Expect = 2e-12, Method: Composition-based stats.
Identities = 32/210 (15%), Positives = 66/210 (31%), Gaps = 17/210 (8%)
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYI 454
+ T+ + A V +++ + + W ++ +
Sbjct 797 HPFTVPADECFSEVSKYRTCFSAAHQALPAAVRNVEVSSISKDSATISWEDLEANIIVFR 856
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
++ L +K + + + R +L +K Y + VT + G G P +
Sbjct 857 VQ---LFEKGGNLIKTENSSADIFRFI---DLEPNKDYSVRVTAINFLGEGPPSWNATFT 910
Query 515 KQAP-------PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR---NYTIFYRTIIGN 564
+ P +R + WD + V + YTI+Y +
Sbjct 911 TKPAQIYEGDRPVAPEKLRISWNSGPRVNVTWDPVSVRRNAEVVTKPIEYTIYYLDTEQS 970
Query 565 ETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
T + ++ T + L D LY V + A
Sbjct 971 STWTTLRTNQTWVVMRDLRKDALYYVYVTA 1000
Score = 63.0 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 47/270 (17%), Positives = 88/270 (33%), Gaps = 31/270 (11%)
Query 382 VNATKLTVNLT----NDRYLATLTVRNLVGKSDAAVLTIPACDFQATH------------ 425
VN T+ V L+ + RY+ +T RN G S +V I + +
Sbjct 426 VNTTERCVTLSDLRSSTRYIVYVTARNEYGTSVPSVRNIASTNVHMVKNNASLPDSMKCC 485
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKKYIL----EWCVLSDKAPCITDWQQEDGTVHRT- 480
++ +F M V S EW +S PCI D + +
Sbjct 486 TDANVTSFCSSKMCNVAEDPSSFSTITIATTCRAEWPKVS---PCIADGRNHTDCCLKKG 542
Query 481 YLRGNLA--ESKCYLITVTPVYADGPGSPESIKAYLK--QAPPSKGPTVRTKKVGKNEAV 536
L + V V + + + PS V ++ +
Sbjct 543 VQHDCLEICSGSTKELGVHSVLCLNLDLQAIYQCIRQGYETHPSAPGNVTISELTAHSVT 602
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
++W + + + NYT+F R E V + + + L D+ Y++ + +++
Sbjct 603 VQWTE--PNSNAHLVENYTLFIRKNEHGEAVRTVKNVISPHVELGLDPDSEYVLTLQSHS 660
Query 597 DEG-GKDGPEFTFTTPKFAQGEIEAIVVPV 625
G F+T + + I P+
Sbjct 661 ANGTSLPSTAKLFSTLPTTRPPLCTIGEPI 690
>sp|Q63518|MYPC1_RAT Myosin-binding protein C, slow-type (Fragment)
OS=Rattus norvegicus OX=10116 GN=Mybpc1 PE=1 SV=1
Length=621
Score = 81.8 bits (200), Expect = 1e-14, Method: Composition-based stats.
Identities = 54/359 (15%), Positives = 94/359 (26%), Gaps = 54/359 (15%)
Query 233 SEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+E + W P IL Y I+ + K +S W ++ + ++F + +
Sbjct 251 TEVGDDWCIMNWEPPVYDGGSPILGYFIERKKKQSSRWMRLNFDLC--KETTFEPKKMIE 308
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
Y RI + G S S+ + P+ + + +V + W
Sbjct 309 GVAYEVRIFAVNAIGISKPSMPSKPFVPLAVTSPPT--------LLAVDSVTDSSVTMKW 360
Query 352 KTLPPFEANGKILDYEVTLTRWKSHL-----------QNYTVNATKLTVNLTNDRYLAT- 399
+ A G + Y + S + L + R T
Sbjct 361 RPPDQIGAAG-LSGYVLEYCFEGSTSAKQSNENGEAANDLPAEDWSLQTQTGSTRPKFTI 419
Query 400 ------------LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
+ N G S+ + P + P
Sbjct 420 TGLPTDAKIFVRVKAINAAGASETKYYSQPILVKEIIEPPKIRIPRHLKQTYI---RRVG 476
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL-RGNLAESKCYLITVTPVYADG-PG 505
E+V I K W+++ + + + N I G
Sbjct 477 EAVNLVI----PFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYD 532
Query 506 SPESIKAYLKQA--------PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
+ Y++ A P V + V L W P D N I YTI
Sbjct 533 LEVKVDKYVENASIDIQIVDRPGPPQAVTIEDVWGENVALTWTP-PKDDGNAAITGYTI 590
Score = 75.3 bits (183), Expect = 1e-12, Method: Composition-based stats.
Identities = 58/340 (17%), Positives = 106/340 (31%), Gaps = 34/340 (10%)
Query 161 KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKV 220
S W F CK P + V EV + A NA+G + V
Sbjct 285 SSRWMRLNFDLCKETTFEP------KKMIEGVAYEVRIFAVNAIGISKPSMPSKPFVPLA 338
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL-KYNIQYR----------TKDASTW 269
+PP L+V + S + + W P L Y ++Y ++
Sbjct 339 VTSPPTLLAVDSV--TDSSVTMKWRPPDQIGAAGLSGYVLEYCFEGSTSAKQSNENGEAA 396
Query 270 SQIPPED------TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+ +P ED T STR FT+ L + R++ + G +S+
Sbjct 397 NDLPAEDWSLQTQTGSTRPKFTITGLPTDAKIFVRVKAINAAGASETKYYSQPILVKEII 456
Query 324 DRPS-KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
+ P + P + + + ++ P E K E+ +
Sbjct 457 EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI---DKNQINIRNSE 513
Query 383 NATKLTVNLTNDRY--LATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW 440
T + + + L V+ + A + I D + ++ +N +
Sbjct 514 TDTIIFIRKAERSHSGKYDLEVKVDKY-VENASIDIQIVDRPGPPQAVTIEDVWGEN-VA 571
Query 441 VEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
+ WT P++ I + + +W HRT
Sbjct 572 LTWTPPKDDGNAAITGYTIQKADKKS-MEWFAVIEHYHRT 610
Score = 66.4 bits (160), Expect = 7e-10, Method: Composition-based stats.
Identities = 37/232 (16%), Positives = 72/232 (31%), Gaps = 27/232 (12%)
Query 394 DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKY 453
D + + ++N G+ A + + ++ D + + W P
Sbjct 215 DSGVYNINLKNEAGE-AHASIKLRLWISLILRLAPNVTEVGDDWCI-MNWEPPVYDGGSP 272
Query 454 ILEWCVLSDKAPCITDWQQE--DGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPE-SI 510
IL + + K + W + D T+ + E Y + + V A G P
Sbjct 273 ILGYFI-ERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 331
Query 511 KAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY------RTIIGN 564
K ++ A S + V + ++W G + Y + Y N
Sbjct 332 KPFVPLAVTSPPTLLAVDSVTDSSVTMKWRPPDQIGAAG-LSGYVLEYCFEGSTSAKQSN 390
Query 565 ET--------------AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
E S+ ++T++ L +D VR+ A G +
Sbjct 391 ENGEAANDLPAEDWSLQTQTGSTRPKFTITGLPTDAKIFVRVKAINAAGASE 442
Score = 40.6 bits (93), Expect = 0.074, Method: Composition-based stats.
Identities = 22/136 (16%), Positives = 44/136 (32%), Gaps = 5/136 (4%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKC---MDYFHVNANYIVWKTNHFTIPKEQYTIINRTAS 87
I P + H T + + E + + + WK + I K Q I N
Sbjct 456 IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 515
Query 88 SVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD 147
++ F A + ++ I I P P+ ++ G+ + W
Sbjct 516 TIIFIRKAERSHSGKYDLEVKVDKYVENASIDIQIVDRPGPPQAVTIEDVWGENVALTWT 575
Query 148 GGRETHLE--TNFTLK 161
++ T +T++
Sbjct 576 PPKDDGNAAITGYTIQ 591
>sp|P50899|GUXB_CELFA Exoglucanase B OS=Cellulomonas fimi (strain
ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980
/ NCTC 7547) OX=590998 GN=cbhB PE=1 SV=1
Length=1090
Score = 81.8 bits (200), Expect = 2e-14, Method: Composition-based stats.
Identities = 47/297 (16%), Positives = 86/297 (29%), Gaps = 36/297 (12%)
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL 397
+ + W + ++ Y+V R + + T + T + Y
Sbjct 711 QAGVVTSTEATISWTA---STDDTRVTGYDVY--RGATKVGTATTTSFTDTGLTASTAYA 765
Query 398 ATLTVRNLVG--KSDAAVLTIPA----CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK 451
T+ + G + +A LT+ D A + N + + W+ ++
Sbjct 766 YTVRAFDAAGNVSAPSAALTVTTKATPSDTTAPSVPAITSSSSTANSVTIGWSASTDNAG 825
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES-- 509
L + A + T T+ L S Y TV G S S
Sbjct 826 GSGLAGYDVYRGA------TRVAQTTALTFTDTGLTASTAYEYTVRARDVAGNVSAPSTA 879
Query 510 IKAYLKQ------APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
+ K PS + V + L W+ D ++ Y ++
Sbjct 880 VSVTTKSDTTPDTTAPSVPAGLAAMTVTETSVALTWNAS-TDTGGSGLKGYDVYRGATRV 938
Query 564 NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT----TPKFAQG 616
T + YT + LT+ T Y + A + G + TP+
Sbjct 939 GST------TTASYTDTGLTAATAYQYTVRATDNAGNVSAASAALSVTTKTPQTGGS 989
Score = 78.7 bits (192), Expect = 2e-13, Method: Composition-based stats.
Identities = 51/310 (16%), Positives = 89/310 (29%), Gaps = 33/310 (11%)
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
S+ ++WT + + Y++ YR +T +SFT L T
Sbjct 715 VTSTEATISWTASTD-DTRVTGYDV-YRGATKVG---------TATTTSFTDTGLTASTA 763
Query 295 YVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL 354
Y + +R G S S + T PS + S + +V + W
Sbjct 764 YAYTVRAFDAA--GNVSAPSAALTVTTK-ATPSDTTAPSVPAITSSSSTANSVTIGWSAS 820
Query 355 PPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVL 414
+ Y+V R + + T T + Y T+ R++ G A
Sbjct 821 TDNAGGSGLAGYDVY--RGATRVAQTTALTFTDTGLTASTAYEYTVRARDVAGNVSAPST 878
Query 415 TIPACDFQATHPVMDLKAFP--------KDNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
+ T P + P + + + W ++ + + V
Sbjct 879 AVSVTTKSDTTPDTTAPSVPAGLAAMTVTETSVALTWNASTDTGGSGLKGYDVY------ 932
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG--PT 524
+ T +Y L + Y TV G S S + P G +
Sbjct 933 -RGATRVGSTTTASYTDTGLTAATAYQYTVRATDNAGNVSAASAALSVTTKTPQTGGSCS 991
Query 525 VRTKKVGKNE 534
V N
Sbjct 992 VAYNASSWNS 1001
Score = 69.9 bits (169), Expect = 8e-11, Method: Composition-based stats.
Identities = 49/313 (16%), Positives = 89/313 (28%), Gaps = 31/313 (10%)
Query 132 LSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF 191
L V + W + T + + A + DT + +
Sbjct 710 LQAGVVTSTEATISWTASTDDTRVTGYDVYRGATKVGTATTTSFTDTGLTAS-------- 761
Query 192 VNIEVWVEAENALGKVTSDHINFDPVYKVKPN---PPHNLSVINSEELSSILKLTWTNPS 248
V A +A G V++ K P+ P ++ +S ++ + + W+ +
Sbjct 762 TAYAYTVRAFDAAGNVSAPSAALTVTTKATPSDTTAPSVPAITSSSSTANSVTIGWSAST 821
Query 249 IK--SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ Y++ YR + T +FT L T Y + +R
Sbjct 822 DNAGGSGLAGYDV-YRGATRVAQT---------TALTFTDTGLTASTAYEYTVRARDVA- 870
Query 307 KGYWSDWSEEASGITY-EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G S S S T + P + T +V L W +G +
Sbjct 871 -GNVSAPSTAVSVTTKSDTTPDTTAPSVPAGLAAMTVTETSVALTWNASTDTGGSG-LKG 928
Query 366 YEVTLTRWK-SHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
Y+V + + T LT Y T+ + G AA +
Sbjct 929 YDVYRGATRVGSTTTASYTDTGLTAA---TAYQYTVRATDNAGNVSAASAALSVTTKTPQ 985
Query 425 HPVMDLKAFPKDN 437
A+ +
Sbjct 986 TGGSCSVAYNASS 998
Score = 68.0 bits (164), Expect = 3e-10, Method: Composition-based stats.
Identities = 35/221 (16%), Positives = 63/221 (29%), Gaps = 23/221 (10%)
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
+ WT + + + + V + ++ L S
Sbjct 713 GVVTSTEATISWTASTDDTR--VTGYDVY-------RGATKVGTATTTSFTDTGLTASTA 763
Query 492 YLITVTPVYADG-PGSPESIKAYLKQAPPS-----KGPTVRTKKVGKNEAVLEWDQLPVD 545
Y TV A G +P + +A PS P + + N + W +
Sbjct 764 YAYTVRAFDAAGNVSAPSAALTVTTKATPSDTTAPSVPAITSSSSTANSVTIGWSASTDN 823
Query 546 VQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG--GKDG 603
+ Y ++ ++ +T + LT+ T Y + A G
Sbjct 824 AGGSGLAGYDVYRGA------TRVAQTTALTFTDTGLTASTAYEYTVRARDVAGNVSAPS 877
Query 604 PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
+ TT + A VP LA + T V +N
Sbjct 878 TAVSVTTKSDTTPDTTAPSVPAGLAAMTVTETSVALTWNAS 918
Score = 35.2 bits (79), Expect = 3.8, Method: Composition-based stats.
Identities = 19/102 (19%), Positives = 32/102 (31%), Gaps = 10/102 (10%)
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLT 583
++ V EA + W D + + Y ++ + + LT
Sbjct 709 GLQAGVVTSTEATISWTASTDDTR---VTGYDVYRGATKVGTATTTSFTD------TGLT 759
Query 584 SDTLYMVRMAAYTDEGGKDGPEFTFT-TPKFAQGEIEAIVVP 624
+ T Y + A+ G P T T K + A VP
Sbjct 760 ASTAYAYTVRAFDAAGNVSAPSAALTVTTKATPSDTTAPSVP 801
>sp|Q9MYZ9|EPOR_PIG Erythropoietin receptor OS=Sus scrofa OX=9823
GN=EPOR PE=2 SV=1
Length=509
Score = 81.1 bits (198), Expect = 2e-14, Method: Composition-based stats.
Identities = 42/207 (20%), Positives = 76/207 (37%), Gaps = 16/207 (8%)
Query 129 PKNLSCIVNEGKKMRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRD-------TPT 180
P+ L C + + C W+ G +++ + + C +
Sbjct 47 PEELLCFTERLEDLVCFWEEAGSAGVGPEDYSFSYQLEGEPWKPCHLHQGPTARGSVRFW 106
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
T FV +E+ V ++ H V +PP L +EE S +
Sbjct 107 CSLPTADTSSFVPLELRVTEVSS--GAPRYHRIIHINEVVLLDPPAGLLARRAEE-SGHV 163
Query 241 KLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
L W P +++Y + T++A+ + + R+ + +L+ T Y F +
Sbjct 164 VLRWLPPPGAPMASLIRYEVNISTENAAG--GVQRVEILDGRTECVLSNLRGGTRYTFMV 221
Query 300 RCM--KEDGKGYWSDWSEEASGITYED 324
R + G+WS WSE AS +T D
Sbjct 222 RARMAEPSFGGFWSAWSEPASLLTASD 248
Score = 46.8 bits (109), Expect = 8e-04, Method: Composition-based stats.
Identities = 35/136 (26%), Positives = 48/136 (35%), Gaps = 6/136 (4%)
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT--IIGNETAVNVDSSHTEYTLSSLTSDT 586
VL W P IR Y + T G V + TE LS+L T
Sbjct 157 AEESGHVVLRWLPPPGAPMASLIR-YEVNISTENAAGGVQRVEILDGRTECVLSNLRGGT 215
Query 587 LYMVRMAAYTDEGGKDGPEFTFTTPK---FAQGEIEAIVVPVCLAFLLTTLLGVLFCFNK 643
Y + A E G ++ P A I+ + L+ LL VL +
Sbjct 216 RYTFMVRARMAEPSFGGFWSAWSEPASLLTASDLDPLILTLSLILVLILLLLAVLALLSH 275
Query 644 RDLIKKHIWPNVPDPS 659
R +K+ IWP +P P
Sbjct 276 RRTLKQKIWPGIPSPE 291
Score = 37.1 bits (84), Expect = 0.91, Method: Composition-based stats.
Identities = 28/209 (13%), Positives = 56/209 (27%), Gaps = 19/209 (9%)
Query 308 GYWSDWSEEASGITYEDR-PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK---I 363
S S +A + ++ P T+ + W+ G
Sbjct 24 WAPSPNSPDAKFESKAALLAARGPEELL----CFTERLEDLVCFWEEA-GSAGVGPEDYS 78
Query 364 LDYEVTLTRWKS---HLQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSDAA----VL 414
Y++ WK H + + +L L +R S A ++
Sbjct 79 FSYQLEGEPWKPCHLHQGPTARGSVRFWCSLPTADTSSFVPLELRVTEVSSGAPRYHRII 138
Query 415 TIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED 474
I + + + + + W P + ++ + V Q+ +
Sbjct 139 HINEVVLLDPPAGLLARRAEESGHVVLRWLPPPGAPMASLIRYEVNISTENAAGGVQRVE 198
Query 475 GTVHRT-YLRGNLAESKCYLITVTPVYAD 502
RT + NL Y V A+
Sbjct 199 ILDGRTECVLSNLRGGTRYTFMVRARMAE 227
>sp|A0MSX9|IL7RA_HORSE Interleukin-7 receptor subunit alpha OS=Equus
caballus OX=9796 GN=IL7R PE=2 SV=1
Length=458
Score = 79.9 bits (195), Expect = 3e-14, Method: Composition-based stats.
Identities = 31/124 (25%), Positives = 58/124 (47%), Gaps = 7/124 (6%)
Query 204 LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS-ILKLTWTNPSIKSVIILKYNIQYR 262
LG + V +VKP P ++ VI EE + ++ ++ K V L + + YR
Sbjct 111 LGGKHITCQKLNIVKRVKPEAPFDVKVIYREEANEFVVTFNTSHLQKKYVKDLLHEVVYR 170
Query 263 -TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED--GKGYWSDWSEEASG 319
K+ + W + + +ST+ + + L+P Y ++R + +G+WS+WS +
Sbjct 171 LEKNENDWMHV---NISSTKLTLLQRKLQPNAMYEIKVRSIPNTNYFEGFWSEWSPSSHF 227
Query 320 ITYE 323
T E
Sbjct 228 RTPE 231
Score = 59.5 bits (142), Expect = 7e-08, Method: Composition-based stats.
Identities = 25/111 (23%), Positives = 54/111 (49%), Gaps = 9/111 (8%)
Query 556 IFYRTIIGNETAVNVDSSHTEYTL--SSLTSDTLYMVRMAAYTDEGGKDG------PEFT 607
+ YR ++V+ S T+ TL L + +Y +++ + + +G P
Sbjct 167 VVYRLEKNENDWMHVNISSTKLTLLQRKLQPNAMYEIKVRSIPNTNYFEGFWSEWSPSSH 226
Query 608 FTTPKFAQGEIEAIVVPVC-LAFLLTTLLGVLFCFNKRDLIKKHIWPNVPD 657
F TP+ G+++ +++ + ++F L+ +L C + IK +WP++PD
Sbjct 227 FRTPENNSGKMDPVLLIISIVSFFSVALMVILACVLWKKRIKPIVWPSLPD 277
>sp|P97924|KALRN_RAT Kalirin OS=Rattus norvegicus OX=10116 GN=Kalrn
PE=1 SV=3
Length=2959
Score = 81.4 bits (199), Expect = 3e-14, Method: Composition-based stats.
Identities = 46/207 (22%), Positives = 75/207 (36%), Gaps = 21/207 (10%)
Query 132 LSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV-DYSTVY 190
L C K W G + L+T+ + AT+ + C + T C + +
Sbjct 2463 LQCKACGRPKPTITWKGPDQNILDTD----NSSATYTISSCDSGESTLKICNLMPQDSGI 2518
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SI 249
+ I A N G ++ + P P+ I E + + L W P S
Sbjct 2519 YTCI-----ATNDHGTASTSAT---VKVQGVPAAPNRP--IAQERSCTSVILRWLPPAST 2568
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT-VQDLKPFTEYVFRIRCMKEDGKG 308
+ I Y ++YR + + W Q AST ++ ++DL P Y FR+ G
Sbjct 2569 GNCTISGYTVEYREEGSQVWQQ----SVASTLDTYLVIEDLSPGCPYQFRVSASNPWGIS 2624
Query 309 YWSDWSEEASGITYEDRPSKAPSFWYK 335
S+ SE Y+ A W +
Sbjct 2625 LPSEPSEFVHLPEYDAAADGATISWKE 2651
Score = 69.9 bits (169), Expect = 1e-10, Method: Composition-based stats.
Identities = 41/267 (15%), Positives = 75/267 (28%), Gaps = 26/267 (10%)
Query 353 TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
P + G + T + +S + N + +N + +A +
Sbjct 2398 PRKPKDILGNKASVKETNSSEESECDDLDPNTSMEILNPNFIQEVAP----------EFL 2447
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQ 472
V + ++ KA + + W P +++ L T
Sbjct 2448 VPLVDVTCLLGDTVLLQCKACGRPKPT-ITWKGPDQNI---------LDTDNSSATYTIS 2497
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGK 532
+ T NL + T G S + Q P+ ++
Sbjct 2498 SCDSGESTLKICNLMPQDSGIYTCIATNDHGTASTSATVKV--QGVPAAPNRPIAQERSC 2555
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY-TLSSLTSDTLYMVR 591
+L W P N I YT+ YR +V S+ Y + L+ Y R
Sbjct 2556 TSVILRWLP-PASTGNCTISGYTVEYREEGSQVWQQSVASTLDTYLVIEDLSPGCPYQFR 2614
Query 592 MAAYTDEG--GKDGPEFTFTTPKFAQG 616
++A G P P++
Sbjct 2615 VSASNPWGISLPSEPSEFVHLPEYDAA 2641
Score = 69.9 bits (169), Expect = 1e-10, Method: Composition-based stats.
Identities = 34/206 (17%), Positives = 64/206 (31%), Gaps = 20/206 (10%)
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL 397
G + WK + N ILD + + + + + K+ + D +
Sbjct 2464 QCKACGRPKPTITWKGP---DQN--ILDTDNSSATYTISSCDSGESTLKICNLMPQDSGI 2518
Query 398 ATLTVRNLVGK-SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
T N G S +A + + P+ ++ + + W P + I
Sbjct 2519 YTCIATNDHGTASTSATVKVQGVPAAPNRPIAQERSC---TSVILRWLPPASTGNCTISG 2575
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
+ V + WQQ + TYL +L+ Y V+ G P
Sbjct 2576 YTVEYREEGSQV-WQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLPSE------ 2628
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQ 541
PS+ + + A + W +
Sbjct 2629 ---PSEFVHLPEYDAAADGATISWKE 2651
Score = 42.5 bits (98), Expect = 0.025, Method: Composition-based stats.
Identities = 28/228 (12%), Positives = 53/228 (23%), Gaps = 44/228 (19%)
Query 35 SPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDI 94
L C I WK I++ SS T+T
Sbjct 2452 DVTCLLGDTVLLQC-------KACGRPKPTITWKGPDQ-------NILDTDNSSATYTIS 2497
Query 95 ASLNIQLTCNILTFGQLEQNVY-------------GITIISGLPPEKPKNLSCIVNEGKK 141
+ + + T I + +Y T+ P P
Sbjct 2498 SCDSGESTLKICNLMPQDSGIYTCIATNDHGTASTSATVKVQGVPAAPNRPIAQERSCTS 2557
Query 142 MRCEWDGGRETHLETN--FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
+ W T T +T++ + T ++ + V
Sbjct 2558 VILRWLPPASTGNCTISGYTVEYREEGSQVWQQSVASTLDTYLVIE-DLSPGCPYQFRVS 2616
Query 200 AENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
A N G + S+ F + + + + ++W
Sbjct 2617 ASNPWGISLPSEPSEF-------------VHLPEYDAAADGATISWKE 2651
>sp|Q93105|INSR_AEDAE Insulin-like receptor OS=Aedes aegypti OX=7159
GN=InR PE=2 SV=2
Length=1393
Score = 81.1 bits (198), Expect = 3e-14, Method: Composition-based stats.
Identities = 81/558 (15%), Positives = 154/558 (28%), Gaps = 100/558 (18%)
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
P CT V N + +E E+ L D L S
Sbjct 471 PMLCTDRIKAVKKYNPGIEIENESQLESNNGDRAACSITE---------LETSLKSIGSE 521
Query 239 ILKLTWTN--PSIKSVIILKYNIQY--------------RTKDASTWSQIPPEDTA-STR 281
+ W + ++L Y I Y + W D
Sbjct 522 TAIIQWAPFTELSDARMLLGYVIYYIEAPYANVTFFDGRDACNTEGWRLDDISDFNMDKE 581
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
++ + LKP+T+Y + ++ +G S+ T PS ++ +
Sbjct 582 TTKILTQLKPYTQYAYYVKTYTLGSEGLGGQ-SKIKYFTTAPGTPSVVRDVEVSVNKNM- 639
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT-------------VNATKLT 388
+ + W LPP + NG++ +YEV + + V T +
Sbjct 640 -----LTVKW--LPPLKMNGRLKEYEVFIELNADDNEQLMLRDYCEDDKLRDIVPETPTS 692
Query 389 VNLTNDRYLATLTVRN--LVGKSDAAVLTIPACDFQAT--------------HPVMDLKA 432
RN S + TI D + +P++ K
Sbjct 693 APPPKTSICTADQCRNYCKAPTSGGSTGTIDVTDKENQITFEDQLHNYVYIKNPLLRDKT 752
Query 433 FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR-TYLRGNLAESKC 491
+ + + E+ K + K + T+
Sbjct 753 TRRKRSTNLLFPNNTENKKNDTTDRRTEKVKDEPYYQYIFNATNETSITFPLSYFNHYSL 812
Query 492 YLITVTPVYADGPGSPESIKAY-----------------LKQAPPSKGPTVRTKKVGKN- 533
Y+ + G S++ K+ P + N
Sbjct 813 YVFKIRACRHPGDPPAPSVRLVDVELACGNEVFENFRTPKKEGADDIPPESILIEEQSNN 872
Query 534 ---EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYT----LSSLT 583
+ ++W + NG I + + Y+ + T + + S T L+ L
Sbjct 873 TQRQIRVQWKE--PSKPNGPIVKFVVKYQRVDLESVSSTDICIRYSSFNQTRGALLTKLE 930
Query 584 SDTLYMVRMAAYTDE--GGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCF 641
Y +R+ A T G + + G + + + FL + + +
Sbjct 931 PG-NYSIRVMATTIAGDGAPSAARYVLIAKDDSMGTTLIWLGTLIVIFLCSVGFVAFYWY 989
Query 642 NKRDLIKK-HIWPNV-PD 657
R + K+ ++P V PD
Sbjct 990 KYRYMSKQIRMYPEVNPD 1007
>sp|A2CG49|KALRN_MOUSE Kalirin OS=Mus musculus OX=10090 GN=Kalrn
PE=1 SV=1
Length=2964
Score = 81.1 bits (198), Expect = 4e-14, Method: Composition-based stats.
Identities = 45/219 (21%), Positives = 82/219 (37%), Gaps = 31/219 (14%)
Query 130 KNLSCIVNEGKKMRC----------EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTP 179
+++C++ + ++C W G + L+T+ + AT+ + C + T
Sbjct 2450 VDVTCLLGDTVLLQCKACGRPKPSITWKGPDQNILDTD----NSSATYTISSCDSGESTL 2505
Query 180 TSCTV-DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
C + + + I A N G ++ + P P+ I E +
Sbjct 2506 KICNLMPQDSGIYTCI-----AANDHGTASTSAT---VKVQGVPAAPNRP--IAQERSCT 2555
Query 239 ILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT-VQDLKPFTEYV 296
+ L W P S + I Y ++YR + + W Q AST ++ ++DL P Y
Sbjct 2556 SVILRWLPPASTGNCTISGYTVEYREEGSQVWQQ----SVASTLDTYLVIEDLSPGCPYQ 2611
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
FR+ G S+ SE Y+ A W +
Sbjct 2612 FRVSASNPWGISLPSEPSEFVRLPEYDAAADGATISWKE 2650
Score = 71.4 bits (173), Expect = 3e-11, Method: Composition-based stats.
Identities = 42/270 (16%), Positives = 79/270 (29%), Gaps = 29/270 (11%)
Query 356 PFEANGK-----ILDYEVTLTRWKSHLQNYTVN-ATKLTVNLTNDRYLATLTVRNLVGKS 409
EA G IL +V++ S ++ + ++ + N ++ +
Sbjct 2391 KNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEV-------AP 2443
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITD 469
+ V + ++ KA + + W P +++ L T
Sbjct 2444 EFLVPLVDVTCLLGDTVLLQCKACGRPKP-SITWKGPDQNI---------LDTDNSSATY 2493
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKK 529
+ T NL + T G S + Q P+ ++
Sbjct 2494 TISSCDSGESTLKICNLMPQDSGIYTCIAANDHGTASTSATVKV--QGVPAAPNRPIAQE 2551
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY-TLSSLTSDTLY 588
+L W P N I YT+ YR +V S+ Y + L+ Y
Sbjct 2552 RSCTSVILRWLP-PASTGNCTISGYTVEYREEGSQVWQQSVASTLDTYLVIEDLSPGCPY 2610
Query 589 MVRMAAYTDEG--GKDGPEFTFTTPKFAQG 616
R++A G P P++
Sbjct 2611 QFRVSASNPWGISLPSEPSEFVRLPEYDAA 2640
Score = 67.2 bits (162), Expect = 8e-10, Method: Composition-based stats.
Identities = 34/206 (17%), Positives = 64/206 (31%), Gaps = 20/206 (10%)
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL 397
G + WK + N ILD + + + + + K+ + D +
Sbjct 2463 QCKACGRPKPSITWKGP---DQN--ILDTDNSSATYTISSCDSGESTLKICNLMPQDSGI 2517
Query 398 ATLTVRNLVGK-SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE 456
T N G S +A + + P+ ++ + + W P + I
Sbjct 2518 YTCIAANDHGTASTSATVKVQGVPAAPNRPIAQERSC---TSVILRWLPPASTGNCTISG 2574
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPGSPESIKAYLK 515
+ V + WQQ + TYL +L+ Y V+ G P
Sbjct 2575 YTVEYREEGSQV-WQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLPSE------ 2627
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQ 541
PS+ + + A + W +
Sbjct 2628 ---PSEFVRLPEYDAAADGATISWKE 2650
Score = 42.9 bits (99), Expect = 0.019, Method: Composition-based stats.
Identities = 28/228 (12%), Positives = 53/228 (23%), Gaps = 44/228 (19%)
Query 35 SPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDI 94
L C I WK I++ SS T+T
Sbjct 2451 DVTCLLGDTVLLQC-------KACGRPKPSITWKGPDQ-------NILDTDNSSATYTIS 2496
Query 95 ASLNIQLTCNILTFGQLEQNVY-------------GITIISGLPPEKPKNLSCIVNEGKK 141
+ + + T I + +Y T+ P P
Sbjct 2497 SCDSGESTLKICNLMPQDSGIYTCIAANDHGTASTSATVKVQGVPAAPNRPIAQERSCTS 2556
Query 142 MRCEWDGGRETHLETN--FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
+ W T T +T++ + T ++ + V
Sbjct 2557 VILRWLPPASTGNCTISGYTVEYREEGSQVWQQSVASTLDTYLVIE-DLSPGCPYQFRVS 2615
Query 200 AENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
A N G + S+ F + + + + ++W
Sbjct 2616 ASNPWGISLPSEPSEF-------------VRLPEYDAAADGATISWKE 2650
>sp|P33896|INAR1_MOUSE Interferon alpha/beta receptor 1 OS=Mus
musculus OX=10090 GN=Ifnar1 PE=1 SV=2
Length=590
Score = 79.5 bits (194), Expect = 6e-14, Method: Composition-based stats.
Identities = 85/558 (15%), Positives = 178/558 (32%), Gaps = 67/558 (12%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP-EDTASTR 281
PP N+ V ++ + L W++ + ++ +YRTKD + W ++P + T +T+
Sbjct 30 KPPENIDVYIIDDNYT---LKWSSHGESMGSVT-FSAEYRTKDEAKWLKVPECQHTTTTK 85
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
F++ D + + FR+R + + S W+E I + P + +
Sbjct 86 CEFSLLDTNVYIKTQFRVRAEEGNST---SSWNEVDPFIPFYTAHMSPPEVRLEAE---- 138
Query 342 QGYRTVQLVWKTLPPFEAN-----GKILDYEVTLTRWKSHLQNYTVNAT----KLTVNLT 392
+ + + + P + N Y + + + KS T+N+T K+ L
Sbjct 139 --DKAILVH-ISPPGQDGNMWALEKPSFSYTIRIWQ-KSSSDKKTINSTYYVEKIPELLP 194
Query 393 NDRYLATLTV-RNLVGKSD--AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES 449
Y + + K + V I +L+ + ++W +
Sbjct 195 ETTYCLEVKAIHPSLKKHSNYSTVQCISTTVANKMPVPGNLQVDAQGKSYVLKWDYIASA 254
Query 450 VKKYILEWCVLSDKAPCIT---DWQQEDGTVHRTYLRGNLAESKCY--LITVTPVYADGP 504
+ +W K+ + W+ + ++ Y + ++G
Sbjct 255 DVLFRAQWLPGYSKSSSGSRSDKWKPIPTCANVQTTHCVFSQDTVYTGTFFLHVQASEGN 314
Query 505 GS---PESIKAYLKQAPPSKGPTVRTKKVGKNEAV-LEWDQLPVDVQNGFIRNYTIFYRT 560
+ E ++ P + + V + D N Y I +
Sbjct 315 HTSFWSEEKFIDSQKHILPPPPVITVTAMSDTLLVYVNCQDSTCDGLN-----YEIIFWE 369
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
N T ++++ E+TL +L T+Y V+ F+ + +
Sbjct 370 NTSN-TKISMEKDGPEFTLKNLQPLTVYCVQARVLFRALLNKTSN--FSEKLCEKTRPGS 426
Query 621 IVVPVCLAFLLTTLLGVLFCFNKRDLIK---KHIWPNVPDPSKSHIAQWSPHTPPRHNFN 677
+ L V+ + R + K +P + P I ++ PP N
Sbjct 427 FSTIWIITGLGVVFFSVMVLYALRSVWKYLCHVCFPPLKPPR--SIDEFF-SEPPSKNLV 483
Query 678 SKDQMYSDGNFTDVSVVEIEANDKKPFPE------------DLKSLDLFKKEKINTEGHS 725
+ + A + K PE D + ++E + TE
Sbjct 484 LLTAEEHTERCFIIENTDTVAVEVKHAPEEDLRKYSSQTSQDSGNYSNEEEESVGTESGQ 543
Query 726 SGIG----GSSCMSSSRP 739
+ + G C S P
Sbjct 544 AVLSKAPCGGPCSVPSPP 561
Score = 39.5 bits (90), Expect = 0.17, Method: Composition-based stats.
Identities = 39/182 (21%), Positives = 64/182 (35%), Gaps = 18/182 (10%)
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENAL-GKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
T C TVY + V+A S+ D + P PP VI +
Sbjct 288 QTTHCVFSQDTVYTGTFFLHVQASEGNHTSFWSEEKFIDSQKHILPPPP----VITVTAM 343
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
S L + N + L Y I + ++T + + FT+++L+P T Y
Sbjct 344 SDTLLVY-VNCQDSTCDGLNYEIIFWENTSNTKISMEKDG-----PEFTLKNLQPLTVYC 397
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK----IDPSHTQGYRTVQLVWK 352
+ R + S++SE+ T RP + W + ++ VWK
Sbjct 398 VQARVLFRALLNKTSNFSEKLCEKT---RPGSFSTIWIITGLGVVFFSVMVLYALRSVWK 454
Query 353 TL 354
L
Sbjct 455 YL 456
>sp|O60229|KALRN_HUMAN Kalirin OS=Homo sapiens OX=9606 GN=KALRN
PE=1 SV=3
Length=2986
Score = 80.3 bits (196), Expect = 6e-14, Method: Composition-based stats.
Identities = 45/216 (21%), Positives = 72/216 (33%), Gaps = 35/216 (16%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLET-----NFTLKSEWATH---KFADCKAKRDTPTS 181
L C V K W G + L+T +T+ S + K + + +
Sbjct 2488 VILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYT 2547
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
C A N G ++ + P P+ I E + +
Sbjct 2548 CI----------------ATNDHGTTSTSAT---VKVQGVPAAPNRP--IAQERSCTSVI 2586
Query 242 LTWTNPSIK-SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT-VQDLKPFTEYVFRI 299
L W PS + I Y ++YR + + W Q AST ++ ++DL P Y FR+
Sbjct 2587 LRWLPPSSTGNCTISGYTVEYREEGSQIWQQ----SVASTLDTYLVIEDLSPGCPYQFRV 2642
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
G S+ SE Y+ A W +
Sbjct 2643 SASNPWGISLPSEPSEFVRLPEYDAAADGATISWKE 2678
Score = 68.7 bits (166), Expect = 2e-10, Method: Composition-based stats.
Identities = 35/209 (17%), Positives = 64/209 (31%), Gaps = 20/209 (10%)
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTND 394
I G + WK + N ILD + + + + K+ + D
Sbjct 2488 VILQCKVCGRPKPTITWKGP---DQN--ILDTDNSSATYTVSSCDSGEITLKICNLMPQD 2542
Query 395 RYLATLTVRNLVGK-SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKY 453
+ T N G S +A + + P+ ++ + + W P +
Sbjct 2543 SGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQERSC---TSVILRWLPPSSTGNCT 2599
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPGSPESIKA 512
I + V + WQQ + TYL +L+ Y V+ G P
Sbjct 2600 ISGYTVEYREEGSQI-WQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLPSE--- 2655
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
PS+ + + A + W +
Sbjct 2656 ------PSEFVRLPEYDAAADGATISWKE 2678
Score = 66.8 bits (161), Expect = 9e-10, Method: Composition-based stats.
Identities = 41/270 (15%), Positives = 78/270 (29%), Gaps = 29/270 (11%)
Query 356 PFEANGK-----ILDYEVTLTRWKSHLQNYTVN-ATKLTVNLTNDRYLATLTVRNLVGKS 409
EA G IL +V++ S ++ + ++ + N ++ + +
Sbjct 2419 KNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEV-----APEF 2473
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITD 469
++ + + PK + W P +++ L T
Sbjct 2474 LVPLVDVTCLLGDTVILQCKVCGRPKPT---ITWKGPDQNI---------LDTDNSSATY 2521
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKK 529
+ T NL + T G S + Q P+ ++
Sbjct 2522 TVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKV--QGVPAAPNRPIAQE 2579
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY-TLSSLTSDTLY 588
+L W P N I YT+ YR +V S+ Y + L+ Y
Sbjct 2580 RSCTSVILRWLP-PSSTGNCTISGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPY 2638
Query 589 MVRMAAYTDEG--GKDGPEFTFTTPKFAQG 616
R++A G P P++
Sbjct 2639 QFRVSASNPWGISLPSEPSEFVRLPEYDAA 2668
Score = 44.1 bits (102), Expect = 0.008, Method: Composition-based stats.
Identities = 28/228 (12%), Positives = 54/228 (24%), Gaps = 44/228 (19%)
Query 35 SPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDI 94
L C I WK I++ SS T+T
Sbjct 2479 DVTCLLGDTVILQC-------KVCGRPKPTITWKGPDQ-------NILDTDNSSATYTVS 2524
Query 95 ASLNIQLTCNILTFGQLEQNVY-------------GITIISGLPPEKPKNLSCIVNEGKK 141
+ + ++T I + +Y T+ P P
Sbjct 2525 SCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQERSCTS 2584
Query 142 MRCEWDGGRETHLETN--FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
+ W T T +T++ + T ++ + V
Sbjct 2585 VILRWLPPSSTGNCTISGYTVEYREEGSQIWQQSVASTLDTYLVIE-DLSPGCPYQFRVS 2643
Query 200 AENALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
A N G + S+ F + + + + ++W
Sbjct 2644 ASNPWGISLPSEPSEF-------------VRLPEYDAAADGATISWKE 2678
>sp|A2AED3|FNDC7_MOUSE Fibronectin type III domain-containing
protein 7 OS=Mus musculus OX=10090 GN=Fndc7 PE=2 SV=1
Length=737
Score = 79.9 bits (195), Expect = 7e-14, Method: Composition-based stats.
Identities = 69/492 (14%), Positives = 132/492 (27%), Gaps = 75/492 (15%)
Query 119 TIISGLPPEKPKNLSCIVNEGKKMRCEWD--GGRETHLETNFTLKSEWATHKFADCKAKR 176
I S PE P + EW G T++ L +E A
Sbjct 22 VISSKTAPEIPTIDQAYSKISNSITVEWTTVPGA-----TSYLLTAEDGNTIIETTVANS 76
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
+ ++ + + +A G+ + P + S
Sbjct 77 PGTVT-----GLKAATLYQITIRSISASGQSQASSPKQAKTVLAAP------VLEVSSPS 125
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDA--STWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ ++W + + +++ + W + +T +S T L T
Sbjct 126 PDSILVSW----DAVYMAIGFSVSVMRANGLGRIWKE------NTTNTSLTFSSLDAGTL 175
Query 295 YVFRIRCMKEDGK-GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
Y + +G G S + T P+ I G + W
Sbjct 176 YTIKAYAWNANGIPGDDST----RNQRTSPRAPA-------NIQVFFDSGALKASVSWTP 224
Query 354 LPPFEANGKILDY-EVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAA 412
+Y V + + T+++ ++ YL +++ N G S +
Sbjct 225 TEGA------FNYTVVASSDSSQRSCSTTLSSCSISSLQCGTEYLISVSANNDAGSSKSC 278
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQ 472
P A P + L V W+ + Y + +
Sbjct 279 SA--PTLKTVACAPGRVMIQEEPPGHLSVAWSNV--ELGDY---YVAFVKSDDGLEVHCN 331
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGK 532
T Y I+V G + Y P + V
Sbjct 332 TSLTQCNFLSECGFT----YFISVFAYNKAGQSPLGDVFNYT--TAPCCPNDISPVLVSS 385
Query 533 NEAVLEWDQLPVDVQ--NGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMV 590
+ + W + I Y+I V + + TLS+L DT Y V
Sbjct 386 DRVEIAWSPVRGAELYETKAIAGYSI-----------VECNDTAPACTLSALDCDTKYNV 434
Query 591 RMAAYTDEGGKD 602
+ ++++ G +
Sbjct 435 TVYSFSEVRGSN 446
Score = 64.5 bits (155), Expect = 4e-09, Method: Composition-based stats.
Identities = 79/539 (15%), Positives = 147/539 (27%), Gaps = 76/539 (14%)
Query 83 NRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGK-K 141
N T +S+TF+ + + + T + T P P N+ + G K
Sbjct 159 NTTNTSLTFSSLDAGTL-YTIKAYAWNANGIPGDDSTRNQRTSPRAPANIQVFFDSGALK 217
Query 142 MRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAE 201
W T N+T+ + + + + S + + V A
Sbjct 218 ASVSWTP---TEGAFNYTVVASSDSSQRSCSTTLSSCSISSLQCGTE-----YLISVSAN 269
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
N G S P K P V+ EE L + W+ +V + Y + +
Sbjct 270 NDAGSSKS---CSAPTLKTVACAPG--RVMIQEEPPGHLSVAWS-----NVELGDYYVAF 319
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
D ++ + + Y + + G+ D +
Sbjct 320 VKSDDGL-----EVHCNTSLTQCNFLS-ECGFTYFISVFAYNKAGQSPLGDVFNYTT--- 370
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG--KILDYEVTLTRWKSHLQN 379
AP I P R V++ W + E I Y +
Sbjct 371 -------APCCPNDISPVLVSSDR-VEIAWSPVRGAELYETKAIAGYSIV---------E 413
Query 380 YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD--N 437
A T++ + +TV + + L+ + ++K KD +
Sbjct 414 CNDTAPACTLSALDCDTKYNVTVY-SFSEVRGSNLSCSSHFITTAPCSPEIKNISKDAFS 472
Query 438 MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
M+ V W + E + V + + + T G L +VT
Sbjct 473 MINVHWRSTNEGAT-----YTVTAQGKKGLFQ----CSSTGETCRMGGLPCGSM--FSVT 521
Query 498 PVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
V G + + P + +V ++ + W + Y
Sbjct 522 AVAETQAGKSLPSYSVPLETVPCCPAGLTAAQVTQSIINVSW------TAGAVAQTYAAV 575
Query 558 YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-----GKDGPEFTFTTP 611
+ IG + L +T Y V + A + G + P
Sbjct 576 LESYIGQSKC---HTHQNHCLLGCITCGINYTVALKAISSTGLTADCAYQSYSSSVCCP 631
Score = 61.4 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 61/410 (15%), Positives = 123/410 (30%), Gaps = 62/410 (15%)
Query 224 PPHNLSVI-NSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P ++ ++S+ + + WT + +L +D +T + ++ T
Sbjct 28 APEIPTIDQAYSKISNSITVEWTTVPGATSYLLT------AEDGNTIIETTVANSPGT-- 79
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
V LK T Y IR + G+ S T P + +
Sbjct 80 ---VTGLKAATLYQITIRSISASGQSQAS---SPKQAKTVLAAP---------VLEVSSP 124
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT----NDRYLA 398
++ + W + + + V++ R + + N T ++ + Y
Sbjct 125 SPDSILVSWDAVYMA------IGFSVSVMRANGLGRIWKENTTNTSLTFSSLDAGTLYTI 178
Query 399 TLTVRNLVG-KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
N G D + + + + V WT + ++
Sbjct 179 KAYAWNANGIPGDDSTRNQRTSPRAPANIQVFFDSGALK--ASVSWTPTEGAFNYTVV-- 234
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
Q+ T + +L YLI+V+ G S +S A +
Sbjct 235 -------ASSDSSQRSCSTTLSSCSISSLQCGTEYLISVSANNDAG--SSKSCSAPTLKT 285
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTE 576
V ++ + W N + +Y + F ++ G E N +
Sbjct 286 VACAPGRVMIQEEPPGHLSVAWS-------NVELGDYYVAFVKSDDGLEVHCNTSLTQCN 338
Query 577 YTLSSLTS-DTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVVP 624
+ L+ Y + + AY G G F +TT +I ++V
Sbjct 339 F----LSECGFTYFISVFAYNKAGQSPLGDVFNYTTAPCCPNDISPVLVS 384
>sp|Q8VHK6|I13R2_RAT Interleukin-13 receptor subunit alpha-2 OS=Rattus
norvegicus OX=10116 GN=Il13ra2 PE=2 SV=1
Length=385
Score = 78.0 bits (190), Expect = 8e-14, Method: Composition-based stats.
Identities = 45/225 (20%), Positives = 83/225 (37%), Gaps = 25/225 (11%)
Query 84 RTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMR 143
RT S T+ + + T ++G ++ G I +++ CI + +
Sbjct 102 RTHLSEHCTNGSEVQSPWT--EASYGIADEGSLGTKI---------QDMKCIYYNWQYLV 150
Query 144 CEWDGGRETHLETNFTLKSEWAT----HKFADCKAKRDTPTSCTV-DYSTVYFVNIEVWV 198
C W G+ H +TN+T+ + + AD + C + + + + + + V
Sbjct 151 CSWKPGKTVHSDTNYTMFFWYEGLDHALQCADYLQDNEKNVGCKLSNLDSSDYKDFFIRV 210
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKY 257
+ L + S ++ F VKP PP L + + +++ W+ P Y
Sbjct 211 NGSSKLEPIRSSYMVFQLQNIVKPLPPEFLHISVENSID--IRMKWSTPGGPIPPSCYTY 268
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
I R D S S D R + +DL F +RC
Sbjct 269 EIVVREDDISWESATDKNDMKLKRRANESEDL------CFFVRCK 307
Score = 63.7 bits (153), Expect = 3e-09, Method: Composition-based stats.
Identities = 50/295 (17%), Positives = 97/295 (33%), Gaps = 32/295 (11%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNP---SIKSVIILKYNIQYRTKDASTWSQIPPED 276
+K NPP + +++ L L L W P L+Y ++YR D+ +W I +
Sbjct 26 IKVNPPQDFEILD-PGLLGYLYLQWKPPVVMDNFKECKLEYELKYRNVDSDSWKTIITRN 84
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKE--DGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
DL E R + +G S W+E + GI E
Sbjct 85 LIYKDG----FDLNKGIEGKIRTHLSEHCTNGSEVQSPWTEASYGIADEGSLGTKIQDMK 140
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--------RWKSHLQNYTVNATK 386
I + + WK ++ +Y + + +LQ+ N
Sbjct 141 CIYYNWQ----YLVCSWKPGKTVHSD---TNYTMFFWYEGLDHALQCADYLQDNEKNVGC 193
Query 387 LTVNLTNDRYLATLTVRNLVGKSDA---AVLTIPACDFQATHPVMDLKAFPKDNM-LWVE 442
NL + Y N K + + + + P L ++++ + ++
Sbjct 194 KLSNLDSSDYKDFFIRVNGSSKLEPIRSSYMVFQLQNIVKPLPPEFLHISVENSIDIRMK 253
Query 443 WTTPRESVKKYILEWCVLSDKAPCITDWQQ-EDGTVHRTYLRGNLAESKCYLITV 496
W+TP + + ++ + W+ D + R N +E C+ +
Sbjct 254 WSTPGGPIPPSCYTYEIVVRED--DISWESATDKNDMKLKRRANESEDLCFFVRC 306
>sp|Q2KL21|EPOR_CANLF Erythropoietin receptor OS=Canis lupus familiaris
OX=9615 GN=EPOR PE=2 SV=1
Length=508
Score = 78.4 bits (191), Expect = 1e-13, Method: Composition-based stats.
Identities = 41/208 (20%), Positives = 77/208 (37%), Gaps = 17/208 (8%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHL-ETNFTLKSEWATHKFADCKAKRD-------TP 179
P+ L C + + C W+ + N++ + + C +
Sbjct 46 APEELLCFTERLEDLVCFWEEAASAGVGPDNYSFFYQLEGEPWKTCSLHQAPTTRGAVRF 105
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
T FV +E+ A ++ + I+ + V +PP L ++E +
Sbjct 106 WCSLPTADTSSFVPLELRATAVSSGALLYRRIIHIN--EVVLLDPPAGLLARRADEGGHV 163
Query 240 LKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ L W P V +++Y + A ++ D R+ + +L+ T Y F
Sbjct 164 V-LRWLPPPGAPVASLIRYEVNISGSVAGGSQKVEILDG---RTECVLSNLRGGTRYTFM 219
Query 299 IRCM--KEDGKGYWSDWSEEASGITYED 324
+R + G+WS WSE AS +T D
Sbjct 220 VRARMAEPSFGGFWSAWSEPASLLTASD 247
Score = 53.3 bits (126), Expect = 7e-06, Method: Composition-based stats.
Identities = 47/200 (24%), Positives = 71/200 (36%), Gaps = 25/200 (13%)
Query 535 AVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
VL W P IR Y + ++ G V + TE LS+L T Y +
Sbjct 163 VVLRWLPPPGAPVASLIR-YEVNISGSVAGGSQKVEILDGRTECVLSNLRGGTRYTFMVR 221
Query 594 AYTDEGGKDGPEFTFTTPK---FAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKH 650
A E G ++ P A I+ + L+ LL VL + R +K+
Sbjct 222 ARMAEPSFGGFWSAWSEPASLLTASDLDPLILTLSLILVLILLLLAVLALLSHRRTLKQK 281
Query 651 IWPNVPDPS--------------------KSHIAQWSPHTPPRHNFNSKDQMYSDGNFTD 690
IWP +P P WSP TP + + ++ S+ +
Sbjct 282 IWPGIPSPESEFEGLFTTHKGNFQLWLYQNEGCLWWSPCTPLAEDPPAPLEVLSERCWGA 341
Query 691 VSVVEIEANDKKPFPEDLKS 710
VE A+D+ P E + S
Sbjct 342 PQAVEPGADDEGPLLEPVGS 361
Score = 37.1 bits (84), Expect = 0.76, Method: Composition-based stats.
Identities = 23/148 (16%), Positives = 42/148 (28%), Gaps = 9/148 (6%)
Query 364 LDYEVTLTRWKS---HLQNYTVNATKLTVNL----TNDRYLATLTVRNLVGKSDAAVLTI 416
Y++ WK+ H T A + +L T+ L + + I
Sbjct 79 FFYQLEGEPWKTCSLHQAPTTRGAVRFWCSLPTADTSSFVPLELRATAVSSGALLYRRII 138
Query 417 PACDFQATHPVMDLKAFPKDNM--LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED 474
+ P L A D + + W P + ++ + V + + E
Sbjct 139 HINEVVLLDPPAGLLARRADEGGHVVLRWLPPPGAPVASLIRYEVNISGSVAGGSQKVEI 198
Query 475 GTVHRTYLRGNLAESKCYLITVTPVYAD 502
+ NL Y V A+
Sbjct 199 LDGRTECVLSNLRGGTRYTFMVRARMAE 226
>sp|Q15746|MYLK_HUMAN Myosin light chain kinase, smooth muscle
OS=Homo sapiens OX=9606 GN=MYLK PE=1 SV=4
Length=1914
Score = 79.1 bits (193), Expect = 2e-13, Method: Composition-based stats.
Identities = 46/212 (22%), Positives = 74/212 (35%), Gaps = 28/212 (13%)
Query 142 MRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAE 201
+ C W +K + K + S + + E
Sbjct 1267 ITCTW-------------MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVE 1313
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT-NPSIKSVIILKYNIQ 260
N LG + + KP+PP + S+ SS L L+W + + Y+I+
Sbjct 1314 NKLGSRQAQ---VNLTVVDKPDPPAG-TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
Query 261 YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
TW ++ +SF VQDL P EY FR+R + G S+ S+E+
Sbjct 1370 IWDSANKTWKEL----ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT---SEPSQESELT 1422
Query 321 TYEDRPSKAPSFWYKIDPSH---TQGYRTVQL 349
T ++P + D YRTV +
Sbjct 1423 TVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454
Score = 46.0 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 23/149 (15%), Positives = 40/149 (27%), Gaps = 5/149 (3%)
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+ + + T L CY + V ++ K PP+
Sbjct 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQA-QVNLTVVDKPDPPAGT 1337
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
P + + L W +++Y+I T + + L
Sbjct 1338 P--CASDIRSSSLTLSW-YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDL 1394
Query 583 TSDTLYMVRMAAYTDEG-GKDGPEFTFTT 610
D Y R+ A G + E TT
Sbjct 1395 LPDHEYKFRVRAINVYGTSEPSQESELTT 1423
Score = 41.8 bits (96), Expect = 0.044, Method: Composition-based stats.
Identities = 28/215 (13%), Positives = 62/215 (29%), Gaps = 16/215 (7%)
Query 32 SPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTF 91
PE V+ + E W I + ++ + + +
Sbjct 1243 FPEDQKVRAGESV-------ELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
Query 92 TDIASLNIQLTC-NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVN-EGKKMRCEWDGG 149
T +A+ C +L +L + + P+ P C + + W G
Sbjct 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1355
Query 150 RETHLE--TNFTLKS-EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK 206
+++++ + A + + R T + + + V A N G
Sbjct 1356 SYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN---VQDLLPDHEYKFRVRAINVYGT 1412
Query 207 VTSDHINFDPVYKVKPNPPHN-LSVINSEELSSIL 240
+ KP P + + V + +E +
Sbjct 1413 SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
Score = 38.7 bits (88), Expect = 0.31, Method: Composition-based stats.
Identities = 15/124 (12%), Positives = 35/124 (28%), Gaps = 11/124 (9%)
Query 320 ITYEDRPSKAPSFWYKIDPSHT-QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
+T D+P P + ++ L W ++ + Y + + +
Sbjct 1325 LTVVDKPDPP-----AGTPCASDIRSSSLTLSWYGSS-YDGGSAVQSYSIEIWDSANKTW 1378
Query 379 NYTVNATKLTVN----LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP 434
+ N L + Y + N+ G S+ + + + D
Sbjct 1379 KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
Query 435 KDNM 438
D+
Sbjct 1439 DDDE 1442
>sp|G5EGJ9|DEP1_CAEEL Receptor-type tyrosine-protein phosphatase
dep-1 OS=Caenorhabditis elegans OX=6239 GN=dep-1 PE=1 SV=1
Length=1367
Score = 78.7 bits (192), Expect = 2e-13, Method: Composition-based stats.
Identities = 82/531 (15%), Positives = 156/531 (29%), Gaps = 56/531 (11%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P K ++ N G + W + + +T++ + T ++
Sbjct 230 PSPLKEVNINQNAGSCVEVSWQNDEFSGAD-FYTIQYSL-QSTPNNSTNMTIPSTESSIS 287
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ A G S+ + +++P PP + V + L
Sbjct 288 ICDSMLQGEAYQIIATVQKGGQVSEPLITKF--QLRPLPPIDFRVRADLKRGKYKLL--- 342
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV----QDLKPFTEYVFRIRC 301
S I K I + + T+S + L P + F I
Sbjct 343 AELPTSSKIDKCQIT--VAGDEAERSVNYANIEQTKSGHKICWFNFALSPGERFDFSISS 400
Query 302 MKEDGKGYWSDWSEEAS--------GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
M + S + G+T ++ W K + T+ +W
Sbjct 401 MANESASQKLQKSIVLTPAFDFNAFGLTLQESNGGIELIWPKSEVFMTRVKD----IWNK 456
Query 354 LPPFEAN--------GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNL 405
+ E+ G + + TL S V A L L T+T +
Sbjct 457 VVGAESLLNMRITPIGNNDETDKTLKFETSPKNIDPVFAKNLVKGACYRVQLFTVTKTGI 516
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAP 465
+ ++ TI + + + S+ + V
Sbjct 517 ISETRHN-ETIRMSSPAVNVSLESVTRSSATLRIVFSTHHDSTSISNCQMHIVVRDMNGK 575
Query 466 CITDWQ-QEDGTVHRTYLRGNLAESKCYLITVTPVYADG----PGSP------ESIKAYL 514
+ D + Q T L+ Y + + G P P +
Sbjct 576 SVFDKRMQLTATFAPLLNLDGLSPFHKYTVNTQIICGSGSSETPQCPAATRTMRQLSFST 635
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET---AVNVD 571
+Q P+ ++ + + +L W LP + NG + +Y + I +ET V V
Sbjct 636 RQDKPAAVQDLKVEPLNSYSVMLTW--LPPALPNGILTHYAVNVTKIGSDETRTIDVGVS 693
Query 572 SSHTEYT----LSSLTSDTLYMVRMAAYTDEG-GKDGPEF-TFTTPKFAQG 616
S+ +++T + L Y + A T+ G G++ P T + P A
Sbjct 694 SNRSDHTVQVVIDELFGGHTYSFSVRAVTEAGFGENSPVVPTVSMPLMAPP 744
Score = 67.6 bits (163), Expect = 5e-10, Method: Composition-based stats.
Identities = 34/230 (15%), Positives = 68/230 (30%), Gaps = 24/230 (10%)
Query 191 FVNIEVWVEAENALGKVTSDHINFDP---------VYKVKPNPPHNLSVINSEELSSILK 241
F V + G + + KP +L V S +
Sbjct 600 FHKYTVNTQIICGSGSSETPQCPAATRTMRQLSFSTRQDKPAAVQDLKVEPLNSYS--VM 657
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP---EDTASTRSSFTVQDLKPFTEYVFR 298
LTW P++ + I+ Y + + I + + + +L Y F
Sbjct 658 LTWLPPALPNGILTHYAVNVTKIGSDETRTIDVGVSSNRSDHTVQVVIDELFGGHTYSFS 717
Query 299 IRCMKEDGKGYWSDWSEEAS-GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPF 357
+R + E G G S S + P+ AP + + G + + + T
Sbjct 718 VRAVTEAGFGENSPVVPTVSMPLMAPPVPTVAPMIMKE-----SVGSHNMIVRFPTTMFD 772
Query 358 EANGKILDYEVTLTRWKSHLQNY----TVNATKLTVNLTNDRYLATLTVR 403
NG+I + + ++ + + N T + + +
Sbjct 773 NRNGEIKQFAIIVSETTADESINRWIESDNGTYTWQQVQRFDVWPSYVAK 822
Score = 64.9 bits (156), Expect = 3e-09, Method: Composition-based stats.
Identities = 73/488 (15%), Positives = 136/488 (28%), Gaps = 97/488 (20%)
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+ T + E + ++L Y ++ + + G SE T
Sbjct 473 NNDETDKTLKFETSPKNIDPVFAKNLVKGACYRVQLFTVTKTGII-----SETRHNETIR 527
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN 383
+P+ ++ S T+ T+++V+ T + + V + + +
Sbjct 528 ---MSSPAVNVSLE-SVTRSSATLRIVFSTHHDSTSISNCQMHIVVRDMNGKSVFDKRMQ 583
Query 384 ATKLTVNLTN-------DRYLATLTVRNLVGKS-----DAAVLTIPACDFQ----ATHPV 427
T L N +Y + G S AA T+ F V
Sbjct 584 LTATFAPLLNLDGLSPFHKYTVNTQIICGSGSSETPQCPAATRTMRQLSFSTRQDKPAAV 643
Query 428 MDLKAFPKDN-MLWVEWTTPRESVKKYILEWCV------LSDKAPCITDWQQEDGTVHRT 480
DLK P ++ + + W P + + V +
Sbjct 644 QDLKVEPLNSYSVMLTWLPPALP-NGILTHYAVNVTKIGSDETRTIDVGVSSNRSDHTVQ 702
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK-----QAPPSKGPTVRTKKVGKNEA 535
+ L Y +V V G G + + P+ P + + VG +
Sbjct 703 VVIDELFGGHTYSFSVRAVTEAGFGENSPVVPTVSMPLMAPPVPTVAPMIMKESVGSHNM 762
Query 536 VLEWDQLPVDVQNGFIRNYTI--------------------------------------- 556
++ + D +NG I+ + I
Sbjct 763 IVRFPTTMFDNRNGEIKQFAIIVSETTADESINRWIESDNGTYTWQQVQRFDVWPSYVAK 822
Query 557 --------------FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GK 601
+ + +ET + V + L S + Y VR+ +T
Sbjct 823 LQDIQKVKQDVDVSIFEELGEDETCLEVRAD--RICNGPLRSASKYRVRIRLFTSPTLFT 880
Query 602 DGPEFTFTTPKFAQGEIEAI-VVPVCLAFLLTTLLG-VLFCFNKRDLIKKHIWPNVPD-P 658
D P T A I + VV V + ++G + F R + + P
Sbjct 881 DSPPSQVMTTGSATPAIPLLTVVAVLIVIAFVGIVGTIFLFFWNRTKKARLAAAAFKNGP 940
Query 659 SKSHIAQW 666
SK +QW
Sbjct 941 SKEKESQW 948
Score = 42.5 bits (98), Expect = 0.025, Method: Composition-based stats.
Identities = 35/309 (11%), Positives = 84/309 (27%), Gaps = 36/309 (12%)
Query 209 SDHINFDPVYKVKPNPP------HNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYR 262
S + + + P P ++ V +K S + ++I+YR
Sbjct 119 STSLIKEESVVMDPRAPDFRSMDSDIQVAEHNITMRTIK-------NDSYLQDSFSIEYR 171
Query 263 TKDASTWSQI--PPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
+ + + F + +L +Y R+ K+ G S
Sbjct 172 QINPDKKFPVLQILDIPEQKNLEFYLGNLNSGFDYSVRVIAHKD---GMSSRP----WIS 224
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY 380
T +PS + V++ W+ A+ + Y + T S
Sbjct 225 TLTTKPSPLKEVNI-----NQNAGSCVEVSWQNDEFSGADFYTIQYSLQSTPNNSTNMTI 279
Query 381 TVNATKLT-VNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV--MDLKAFPKDN 437
+ ++ + + G + I + P+ +
Sbjct 280 PSTESSISICDSMLQGEAYQIIATVQKG-GQVSEPLITKFQLRPLPPIDFRVRADLKRGK 338
Query 438 MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL---RGNLAESKCYLI 494
+ P S V D+A ++ + T + L+ + +
Sbjct 339 YKLLA-ELPTSSKIDKCQ-ITVAGDEAERSVNYANIEQTKSGHKICWFNFALSPGERFDF 396
Query 495 TVTPVYADG 503
+++ + +
Sbjct 397 SISSMANES 405
>sp|P29294|MYLK_RABIT Myosin light chain kinase, smooth muscle
OS=Oryctolagus cuniculus OX=9986 GN=MYLK PE=1 SV=2
Length=1147
Score = 78.7 bits (192), Expect = 2e-13, Method: Composition-based stats.
Identities = 37/158 (23%), Positives = 66/158 (42%), Gaps = 16/158 (10%)
Query 197 WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT-NPSIKSVIIL 255
+ EN LG + + KP+PP + S+ SS L L+W + +
Sbjct 540 TLLVENKLGSRQAQ---VNLTVVDKPDPPAG-TPCASDIRSSSLTLSWYGSSYDGGSAVQ 595
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y+++ W+++ +SF V+DL P EY FR+R + G S+ S+
Sbjct 596 SYSVEIWDSVDKMWTEL----ATCRSTSFNVRDLLPDREYKFRVRAINVYGT---SEPSQ 648
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQ----GYRTVQL 349
E+ T ++P + ++ + YRTV +
Sbjct 649 ESELTTVGEKPEEPKDEVEEVSDDDEKEPEVDYRTVTV 686
Score = 49.5 bits (116), Expect = 2e-04, Method: Composition-based stats.
Identities = 23/144 (16%), Positives = 44/144 (31%), Gaps = 6/144 (4%)
Query 379 NYTVNATKLTVNLTNDRYL--ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
+ +KLT+ + TL V N +G S A + + D + +
Sbjct 518 ENSEAGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASDIRS 576
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV 496
+ L + W + + V W + ++ +L + Y V
Sbjct 577 SSLTLSWYGSSYDGGSAVQSYSVEIWD-SVDKMWTELATCRSTSFNVRDLLPDREYKFRV 635
Query 497 TPVYADGPGSP--ESIKAYLKQAP 518
+ G P ES + + P
Sbjct 636 RAINVYGTSEPSQESELTTVGEKP 659
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 24/150 (16%), Positives = 46/150 (31%), Gaps = 7/150 (5%)
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+ + + T L CY + V ++ K PP+
Sbjct 510 QDSEHIKVENSEAGSKLTILAARQEHCGCYTLLVENKLGSRQA-QVNLTVVDKPDPPAGT 568
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSS 581
P + + L W +++Y++ + ++ T + S T + +
Sbjct 569 P--CASDIRSSSLTLSW-YGSSYDGGSAVQSYSVEIWDSVDKMWTELATCRS-TSFNVRD 624
Query 582 LTSDTLYMVRMAAYTDEG-GKDGPEFTFTT 610
L D Y R+ A G + E TT
Sbjct 625 LLPDREYKFRVRAINVYGTSEPSQESELTT 654
Score = 39.8 bits (91), Expect = 0.16, Method: Composition-based stats.
Identities = 20/125 (16%), Positives = 40/125 (32%), Gaps = 15/125 (12%)
Query 320 ITYEDRPSKAPSFWYKIDPSHT-QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
+T D+P P + ++ L W ++ + Y V + W S +
Sbjct 556 LTVVDKPDPP-----AGTPCASDIRSSSLTLSWYGSS-YDGGSAVQSYSVEI--WDSVDK 607
Query 379 NYTVNATKLTV------NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA 432
+T AT + L + Y + N+ G S+ + + + D
Sbjct 608 MWTELATCRSTSFNVRDLLPDREYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 667
Query 433 FPKDN 437
D+
Sbjct 668 EVSDD 672
>sp|P33005|KALM_CHICK Anosmin-1 OS=Gallus gallus OX=9031 GN=ANOS1
PE=2 SV=2
Length=675
Score = 78.0 bits (190), Expect = 2e-13, Method: Composition-based stats.
Identities = 29/187 (16%), Positives = 56/187 (30%), Gaps = 24/187 (13%)
Query 435 KDNMLWVEWTT----PRESVKKYILEWCVL--SDKAPCITDWQQEDGTVHRTYLRGNLAE 488
+ L V+W++ E V + T+WQ T ++
Sbjct 190 QSGDLEVKWSSKFNISIEPVIYVVQRRWNQGIHPSEDDATNWQTVAQTTDERVQLSDIRA 249
Query 489 SKCYLITVTPVYADGP----GSPESIKAYLKQAPPSKGPTVRTKKVGKNE-----AVLEW 539
S+ Y V V G + ++ + P +R + N ++ W
Sbjct 250 SRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSAPPAPSNIRIANISANNDGTVNVMITW 309
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGN-------ETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
D + + + +Y +F+ + D L L ++ Y V +
Sbjct 310 DL--PEEPDIPVHHYKVFWSWTYSKYVIPAKKKRRKITDGPQNYVVLEGLQPNSNYNVEL 367
Query 593 AAYTDEG 599
A T G
Sbjct 368 QAVTRWG 374
Score = 74.1 bits (180), Expect = 3e-12, Method: Composition-based stats.
Identities = 73/505 (14%), Positives = 133/505 (26%), Gaps = 103/505 (20%)
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
N G N YK P P + E S L++ W++ S+ + Y +Q
Sbjct 160 NGCGHTCQVPKNL---YKGVPLKPRK-ELKFIELQSGDLEVKWSSKFNISIEPVIYVVQR 215
Query 262 R--------TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
R DA+ W + +T + D++ Y FR+ + G ++
Sbjct 216 RWNQGIHPSEDDATNWQTV----AQTTDERVQLSDIRASRWYQFRVAAVNVHGTRGFTAP 271
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQ-GYRTVQLVWKTLPPFEANGKILDYEVTLTR 372
S+ P APS + S G V + W P E + + Y+V +
Sbjct 272 SKHFRSSKDPSAP-PAPSNIRIANISANNDGTVNVMITWD--LPEEPDIPVHHYKVFWSW 328
Query 373 WKSH-----------LQNYTVNATKLTVNLTNDRYLATLTVRNLVG----KSDAAVLTIP 417
S + + N L N Y L G KS L
Sbjct 329 TYSKYVIPAKKKRRKITDGPQNYVVLEGLQPNSNYNVELQAVTRWGQIRLKSAKVSLHFS 388
Query 418 ACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAP--CITDWQQEDG 475
+ P ++ T R +++ W++ D
Sbjct 389 TAQDNRNNNEQTSAGKPPKGLVDPYPTFQRRKPTRFLKIGTPFYQDNQLQVKVYWKKTDI 448
Query 476 TVHRTYLRGNLAESKC----------------------------YLITVTPVYADGPGSP 507
+++ + L Y +TV P +
Sbjct 449 NMNQFQVHSLLESCVHNDTKGLEKVTELTYENYMILKDLSFSCKYKVTVLPAKSKSRFKA 508
Query 508 ESIKAYLK-----------------QAPPSKGPTVRTKKVGKNEAVL---------EWDQ 541
ESI + P + + ++ W
Sbjct 509 ESIFFVTPSCSAFKEKTHKHINCAAEEVPVLPKVLAKPENLSASFIVQEGNITGHFSWK- 567
Query 542 LPVDVQNGFIRNYTIFYRTIIGNE-----------TAVNVDSSHTEYTLSSLTSDTLYMV 590
+ V + + + + + + + + + H T+ +L LY +
Sbjct 568 ISKAVLHQPMTGFQVTWAEVTTESRQNSLPNSIISQSQILPADHYVLTVPNLRPSMLYRL 627
Query 591 RMAAYTDEGGKDGPEFTFTTPKFAQ 615
+ T G F TP
Sbjct 628 EVQVLTTGGEGPATIKLFRTPDLPP 652
Score = 70.3 bits (170), Expect = 5e-11, Method: Composition-based stats.
Identities = 67/509 (13%), Positives = 130/509 (26%), Gaps = 93/509 (18%)
Query 107 TFGQLEQNVYGIT--IISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHL-ETNFTLKSE 163
+ + + G+P + K L I + + +W + + ++
Sbjct 157 CCSNGCGHTCQVPKNLYKGVPLKPRKELKFIELQSGDLEVKWSSKFNISIEPVIYVVQRR 216
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFVN------IEVWVEAENALGK----VTSDHIN 213
W + T V + + V A N G S H
Sbjct 217 WNQGIHPSEDDATNWQTVAQTTDERVQLSDIRASRWYQFRVAAVNVHGTRGFTAPSKHFR 276
Query 214 FDPVYKVKPNPPHNLSVINSEELSS---ILKLTWTNPSIKSVIILKYNIQY---RTKDAS 267
P P N+ + N + + +TW P + + Y + + +K
Sbjct 277 SSKDPSAPP-APSNIRIANISANNDGTVNVMITWDLPEEPDIPVHHYKVFWSWTYSKYVI 335
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED--- 324
+ + T ++ ++ L+P + Y ++ + G+ T +D
Sbjct 336 PAKKKRRKITDGPQNYVVLEGLQPNSNYNVELQAVTRWGQIRLKSAKVSLHFSTAQDNRN 395
Query 325 --------RP-------------SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
+P K F P + V++ WK + N
Sbjct 396 NNEQTSAGKPPKGLVDPYPTFQRRKPTRFLKIGTPFYQDNQLQVKVYWK---KTDINMNQ 452
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNL------TNDRYLATLTVRNLVGKSDAAVLTI- 416
L + T+LT + +TV KS +I
Sbjct 453 FQVHSLLESCVHNDTKGLEKVTELTYENYMILKDLSFSCKYKVTVLPAKSKSRFKAESIF 512
Query 417 ------------------PACDFQATHPVMDLKAFPKDNMLWV---------EWTTPR-- 447
A + P + K V W +
Sbjct 513 FVTPSCSAFKEKTHKHINCAAEEVPVLPKVLAKPENLSASFIVQEGNITGHFSWKISKAV 572
Query 448 --ESVKKYILEWCVLSDKAP------CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPV 499
+ + + + W ++ ++ I Q H NL S Y + V +
Sbjct 573 LHQPMTGFQVTWAEVTTESRQNSLPNSIISQSQILPADHYVLTVPNLRPSMLYRLEVQVL 632
Query 500 YADGPGSPESIKAYLKQAPP--SKGPTVR 526
G G PP P ++
Sbjct 633 TTGGEGPATIKLFRTPDLPPFLPHRPHLK 661
>sp|P23352|KALM_HUMAN Anosmin-1 OS=Homo sapiens OX=9606 GN=ANOS1
PE=1 SV=3
Length=680
Score = 77.6 bits (189), Expect = 3e-13, Method: Composition-based stats.
Identities = 30/188 (16%), Positives = 58/188 (31%), Gaps = 25/188 (13%)
Query 435 KDNMLWVEWTT----PRESVKKYILEWCV--LSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
+ L V+W++ E V + + T WQ T ++
Sbjct 196 QSGQLEVKWSSKFNISIEPVIYVVQRRWNYGIHPSEDDATHWQTVAQTTDERVQLTDIRP 255
Query 489 SKCYLITVTPVYADG----PGSPESIKAYLKQAPPSKGPTVRTKKVGKNE-----AVLEW 539
S+ Y V V G + ++ + P +R N + W
Sbjct 256 SRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSAPPAPANLRLANSTVNSDGSVTVTIVW 315
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNET--------AVNVDSSHTEYTLSSLTSDTLYMVR 591
D + + + +Y +F+ ++ +++ D L L D Y+V
Sbjct 316 DL--PEEPDIPVHHYKVFWSWMVSSKSLVPTKKKRRKTTDGFQNSVILEKLQPDCDYVVE 373
Query 592 MAAYTDEG 599
+ A T G
Sbjct 374 LQAITYWG 381
Score = 76.4 bits (186), Expect = 7e-13, Method: Composition-based stats.
Identities = 81/504 (16%), Positives = 148/504 (29%), Gaps = 100/504 (20%)
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
N G YK P P + +E S L++ W++ S+ + Y +Q
Sbjct 166 NGCGHTCQVPKTL---YKGVPLKPRK-ELRFTELQSGQLEVKWSSKFNISIEPVIYVVQR 221
Query 262 R--------TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
R DA+ W + +T + D++P Y FR+ + G ++
Sbjct 222 RWNYGIHPSEDDATHWQTV----AQTTDERVQLTDIRPSRWYQFRVAAVNVHGTRGFTAP 277
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
S+ P + ++ G TV +VW P E + + Y+V +
Sbjct 278 SKHFRSSKDPSAPPAPANLRLANSTVNSDGSVTVTIVWD--LPEEPDIPVHHYKVFWSWM 335
Query 374 KSHLQNYTV------------NATKLTVNLTNDRYLATLTVRNLVG----KSDAAVLTIP 417
S N+ L + Y+ L G KS L
Sbjct 336 VSSKSLVPTKKKRRKTTDGFQNSVILEKLQPDCDYVVELQAITYWGQTRLKSAKVSLHFT 395
Query 418 ACDF------------------------QATHPVMDLKAFPKDNMLWVE--WTTPRES-V 450
+ + T P+ F +D L V+ W + V
Sbjct 396 STHATNNKEQLVKTRKGGIQTQLPFQRRRPTRPLEVGAPFYQDGQLQVKVYWKKTEDPTV 455
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESKCYLITVTPVYADGPGSPES 509
+Y + W + T + G H Y+ +L+ S Y +TV P+ E+
Sbjct 456 NRYHVRWFPEACAHNRTTGSEASSGMTHENYIILQDLSFSCKYKVTVQPIRPKSHSKAEA 515
Query 510 IKAYLKQAPPSKGPT-----------------VRTKKVGKNEAVL---------EWDQLP 543
+ KG + + + ++ W
Sbjct 516 VFFTTPPCSALKGKSHKPVGCLGEAGHVLSKVLAKPENLSASFIVQDVNITGHFSWKMAK 575
Query 544 VDVQNGFIRNYTIFYRTIIGNE-----------TAVNVDSSHTEYTLSSLTSDTLYMVRM 592
++ + + + + + + + S H T+ +L TLY + +
Sbjct 576 ANLYQ-PMTGFQVTWAEVTTESRQNSLPNSIISQSQILPSDHYVLTVPNLRPSTLYRLEV 634
Query 593 AAYTDEGGKDGPEFTFTTPKFAQG 616
T G TF TP+
Sbjct 635 QVLTPGGEGPATIKTFRTPELPPS 658
Score = 71.0 bits (172), Expect = 3e-11, Method: Composition-based stats.
Identities = 74/521 (14%), Positives = 140/521 (27%), Gaps = 102/521 (20%)
Query 103 CNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG----GRETHLET-- 156
C G Q T+ G+P + K L + ++ +W E +
Sbjct 163 CCSNGCGHTCQ--VPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEPVIYVVQ 220
Query 157 ---NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK----VTS 209
N+ + A+ D + + V A N G S
Sbjct 221 RRWNYGIHPSEDDATHWQTVAQTTDERVQLTDIRPSRW--YQFRVAAVNVHGTRGFTAPS 278
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSS---ILKLTWTNPSIKSVIILKYNIQY----R 262
H P P NL + NS S + + W P + + Y + +
Sbjct 279 KHFRSSKDPSAPP-APANLRLANSTVNSDGSVTVTIVWDLPEEPDIPVHHYKVFWSWMVS 337
Query 263 TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+K + + T ++S ++ L+P +YV ++ + G+ +
Sbjct 338 SKSLVPTKKKRRKTTDGFQNSVILEKLQPDCDYVVELQAITYWGQTRLKSAKVSLHFTST 397
Query 323 ED------------------------RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE 358
RP++ P + G V++ WK
Sbjct 398 HATNNKEQLVKTRKGGIQTQLPFQRRRPTRPLEV---GAPFYQDGQLQVKVYWKKTEDPT 454
Query 359 ANGKILDYEVTL--------TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS- 409
N Y V S + + + + + +TV+ + KS
Sbjct 455 VN----RYHVRWFPEACAHNRTTGSEASSGMTHENYIILQDLSFSCKYKVTVQPIRPKSH 510
Query 410 ---DAAVLTIPACD--------------------FQATHPVMDLKAFPKDNMLWV----E 442
+A T P C + +L A + +
Sbjct 511 SKAEAVFFTTPPCSALKGKSHKPVGCLGEAGHVLSKVLAKPENLSASFIVQDVNITGHFS 570
Query 443 WTTPR----ESVKKYILEWCVLSDKAP------CITDWQQEDGTVHRTYLRGNLAESKCY 492
W + + + + + W ++ ++ I Q + H NL S Y
Sbjct 571 WKMAKANLYQPMTGFQVTWAEVTTESRQNSLPNSIISQSQILPSDHYVLTVPNLRPSTLY 630
Query 493 LITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN 533
+ V + G G + PPS K +
Sbjct 631 RLEVQVLTPGGEGPATIKTFRTPELPPSSAHRSHLKHRHPH 671
>sp|O18016|IGDB1_CAEEL Ig-like and fibronectin type-III domain-containing
protein 1 OS=Caenorhabditis elegans OX=6239 GN=igdb-1
PE=1 SV=2
Length=1029
Score = 78.0 bits (190), Expect = 3e-13, Method: Composition-based stats.
Identities = 46/290 (16%), Positives = 93/290 (32%), Gaps = 27/290 (9%)
Query 160 LKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYK 219
++ H C + + C + V A+ +V+ F ++
Sbjct 272 VQCASEGHDHLRCCLQEEVSKPCQ---TACMHP---FTVPADECFSEVSKYRTCFSAAHQ 325
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
P N+ V + ++W + I+ + +Q K + I E+ S
Sbjct 326 ALPAAVRNVEVSSI--SKDSATISWEDLEAN---IIVFRVQLFEKGG---NLIKTEN--S 375
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
+ F DL+P +Y R+ + G+G S W+ + + P K+ S
Sbjct 376 SADIFRFIDLEPNKDYSVRVTAINFLGEGPPS-WNATFTTKPAQIYEGDRPVAPEKLRIS 434
Query 340 HTQGYRTVQLVWKTLPP---FEANGKILDYEVTL--TRWKSHLQNYTVNATKLTVNLTND 394
G R V + W + E K ++Y + T S N T + +
Sbjct 435 WNSGPR-VNVTWDPVSVRRNAEVVTKPIEYTIYYLDTEQSSTWTTLRTNQTWVVMRDLRK 493
Query 395 R--YLATLTVR--NLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW 440
Y +T + N +S + + + D + + ++
Sbjct 494 DALYYVYVTAKEDNRTSRSSSIITILAQKDSPGLPEPTIVIEPDHKDGVF 543
Score = 75.3 bits (183), Expect = 2e-12, Method: Composition-based stats.
Identities = 76/499 (15%), Positives = 139/499 (28%), Gaps = 88/499 (18%)
Query 147 DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK 206
D + + T ++EW K + C A T C + V +E+ + LG
Sbjct 7 DPSSFSTITIATTCRAEWP--KVSPCIADGRNHTDCCLKKG-VQHDCLEICSGSTKELGV 63
Query 207 VTSDHINFDPVYK---------VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKY 257
+ +N D P+ P N+++ SE + + + WT P+ + ++ Y
Sbjct 64 HSVLCLNLDLQAIYQCIRQGYETHPSAPGNVTI--SELTAHSVTVQWTEPNSNAHLVENY 121
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
+ R + + S L P +EYV ++ +G S S
Sbjct 122 TLFIRKNEHGE----AVRTVKNVISPHVELGLDPDSEYVLTLQSHSANGT---SLPSTAK 174
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL 377
T P+ P +P + R + P +++
Sbjct 175 LFSTL---PTTRPPLCTIGEPIYMNDGRVMICDAVNPCPNGFRCTGAGSDLSYCCPHDGT 231
Query 378 QNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN 437
+ + + + S +T+P
Sbjct 232 HSSEEFTSCCKEQKMPESCM----------SSCQYNMTLPESC----------------- 264
Query 438 MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH------RTYLRGNLAESKC 491
+E++ ++ D C + +E
Sbjct 265 ---------KENLNTWVQCASEGHDHLRCCLQEEVSKPCQTACMHPFTVPADECFSEVSK 315
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
Y T A P +++ V + K+ A + W+ L I
Sbjct 316 YR---TCFSAAHQALPAAVR------------NVEVSSISKDSATISWEDL-----EANI 355
Query 552 RNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTT 610
+ + GN +SS + L + Y VR+ A G G TFTT
Sbjct 356 IVFRVQLFEKGGNLIK-TENSSADIFRFIDLEPNKDYSVRVTAINFLGEGPPSWNATFTT 414
Query 611 PKFAQGEIEAIVVPVCLAF 629
E + V P L
Sbjct 415 KPAQIYEGDRPVAPEKLRI 433
Score = 74.9 bits (182), Expect = 3e-12, Method: Composition-based stats.
Identities = 32/210 (15%), Positives = 66/210 (31%), Gaps = 17/210 (8%)
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYI 454
+ T+ + A V +++ + + W ++ +
Sbjct 300 HPFTVPADECFSEVSKYRTCFSAAHQALPAAVRNVEVSSISKDSATISWEDLEANIIVFR 359
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
++ L +K + + + R +L +K Y + VT + G G P +
Sbjct 360 VQ---LFEKGGNLIKTENSSADIFRFI---DLEPNKDYSVRVTAINFLGEGPPSWNATFT 413
Query 515 KQAP-------PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR---NYTIFYRTIIGN 564
+ P +R + WD + V + YTI+Y +
Sbjct 414 TKPAQIYEGDRPVAPEKLRISWNSGPRVNVTWDPVSVRRNAEVVTKPIEYTIYYLDTEQS 473
Query 565 ETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
T + ++ T + L D LY V + A
Sbjct 474 STWTTLRTNQTWVVMRDLRKDALYYVYVTA 503
>sp|Q8C310|ROBO4_MOUSE Roundabout homolog 4 OS=Mus musculus OX=10090
GN=Robo4 PE=1 SV=2
Length=1012
Score = 78.0 bits (190), Expect = 3e-13, Method: Composition-based stats.
Identities = 45/242 (19%), Positives = 74/242 (31%), Gaps = 28/242 (12%)
Query 393 NDRYLATLTVRNLVG--KSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV 450
ND N G +S AA ++I H + +N+ + +
Sbjct 201 NDSGTYMCMATNNAGQRESRAARVSIQESQDHKEHLELLAVRIQLENVTLLNPEPVKGPK 260
Query 451 KK--YILEWCVLSDKAPCITD----------------WQQEDGTVHRTYLRGNLAESKCY 492
L W V AP + W + ++ G L + Y
Sbjct 261 PGPSVWLSWKVSGPAAPAESYTALFRTQRSPRDQGSPWTEVLLRGLQSAKLGGLHWGQDY 320
Query 493 LITVTPVYADGPGSPESIKA-YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
V P G ++ L + PS P T + G + W P + NG I
Sbjct 321 EFKVRPSSGRARGPDSNVLLLRLPEQVPSAPPQGVTLRSGNGSVFVSWAPPPAESHNGVI 380
Query 552 RNYTIF-YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
R Y ++ V T+ +++ + Y V++AA T G +T
Sbjct 381 RGYQVWSLGNASLPAANWTVVGEQTQLEIATRLPGS-YCVQVAAVTGAGAG-----ELST 434
Query 611 PK 612
P
Sbjct 435 PV 436
Score = 69.9 bits (169), Expect = 9e-11, Method: Composition-based stats.
Identities = 31/211 (15%), Positives = 55/211 (26%), Gaps = 20/211 (9%)
Query 227 NLSVINSEELSSILKLTWT---NPSIKSVIILKYNIQYRTKD-ASTWSQIPPEDTASTRS 282
N + + + L+W + + Q +D S W+++
Sbjct 252 NPEPVKGPKPGPSVWLSWKVSGPAAPAESYTALFRTQRSPRDQGSPWTEVLLRGL----Q 307
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
S + L +Y F++R +G S E PS P +
Sbjct 308 SAKLGGLHWGQDYEFKVRPSSGRARGPD---SNVLLLRLPEQVPSAPPQ-----GVTLRS 359
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS----HLQNYTVNATKLTVNLTNDRYLA 398
G +V + W P NG I Y+V S + Y
Sbjct 360 GNGSVFVSWAPPPAESHNGVIRGYQVWSLGNASLPAANWTVVGEQTQLEIATRLPGSYCV 419
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMD 429
+ G + + + D
Sbjct 420 QVAAVTGAGAGELSTPVCLLLEQAMEQSARD 450
Score = 47.9 bits (112), Expect = 5e-04, Method: Composition-based stats.
Identities = 30/192 (16%), Positives = 50/192 (26%), Gaps = 24/192 (13%)
Query 326 PSKAPSFWYKIDPSHTQGYRTVQLVWK---TLPPFEANGKILDYEVTLTRWKSHLQNYTV 382
P PS W L WK P E+ + + + S +
Sbjct 259 PKPGPSVW---------------LSWKVSGPAAPAESYTALFRTQRSPRDQGSPWTEVLL 303
Query 383 NA-TKLTVNLTNDRYLATLTVRNLVGK---SDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
+ + VR G+ D+ VL + + + P + +
Sbjct 304 RGLQSAKLGGLHWGQDYEFKVRPSSGRARGPDSNVLLLRLPEQVPSAPPQGVTLRSGNGS 363
Query 439 LWVEWTTPR-ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
++V W P ES I + V S + Y + V
Sbjct 364 VFVSWAPPPAESHNGVIRGYQVWSLGNASLPAANWTVVGEQTQLEIATRLPGS-YCVQVA 422
Query 498 PVYADGPGSPES 509
V G G +
Sbjct 423 AVTGAGAGELST 434
>sp|P17181|INAR1_HUMAN Interferon alpha/beta receptor 1 OS=Homo
sapiens OX=9606 GN=IFNAR1 PE=1 SV=3
Length=557
Score = 77.2 bits (188), Expect = 3e-13, Method: Composition-based stats.
Identities = 85/561 (15%), Positives = 188/561 (34%), Gaps = 67/561 (12%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP-EDTASTRSS 283
P + V ++ L W N S +SV + ++ Y+ W ++ ++ ST+ +
Sbjct 33 PQKVEVDIIDDN---FILRW-NRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCN 88
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID----PS 339
F+ L + E RIR KE+ S W E S + P + +
Sbjct 89 FSSLKLNVYEEIKLRIRAEKEN----TSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVI 144
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA-TKLTVNLTNDRYLA 398
H ++W +G Y + + + S ++ N ++ + +
Sbjct 145 HISPGTKDSVMW------ALDGLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTY 198
Query 399 TLTVRNLVGKS-----DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKY 453
L V+ + S + V I P +++ ++ ++W + +
Sbjct 199 CLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDY-TYANMTF 257
Query 454 ILEW---CVLSDKAPCITDWQQED----GTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
++W + + + W+Q + N+ + YL+ V +
Sbjct 258 QVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSF 317
Query 507 -PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE 565
E IK + P + + + + I++Y + Y I
Sbjct 318 WSEEIKFDTEIQAFLLPPVFNIRSLS-DSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWEN 376
Query 566 T---AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP----KFAQGEI 618
T + T+ T+ +L T+Y V+ A+T + + K
Sbjct 377 TSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSK 436
Query 619 EAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNS 678
++V +C+A + + + ++ + + P P +S
Sbjct 437 IWLIVGICIALFALPFVI----YAAKVFLRCINY------------VFFPSLKPS---SS 477
Query 679 KDQMYSDGNFTDVSVVEIEANDKKP-FPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSS 737
D+ +S+ ++ + E +K E++ ++ ++ E H +S
Sbjct 478 IDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDH-----KKYSSQTS 532
Query 738 RPSISSSDENESSQNTSSTVQ 758
+ S + S+E+ES TS +Q
Sbjct 533 QDSGNYSNEDESESKTSEELQ 553
>sp|Q90369|KALM_COTJA Anosmin-1 OS=Coturnix japonica OX=93934
GN=ANOS1 PE=2 SV=1
Length=674
Score = 77.2 bits (188), Expect = 4e-13, Method: Composition-based stats.
Identities = 29/187 (16%), Positives = 56/187 (30%), Gaps = 24/187 (13%)
Query 435 KDNMLWVEWTT----PRESVKKYILEWCVL--SDKAPCITDWQQEDGTVHRTYLRGNLAE 488
+ L V+W++ E V + T+WQ T ++
Sbjct 190 QSGDLEVKWSSKFNISIEPVIYVVQRRWNQGIHPSEDDATNWQTVAQTTDERVQLSDIRA 249
Query 489 SKCYLITVTPVYADGP----GSPESIKAYLKQAPPSKGPTVRTKKVGKNE-----AVLEW 539
S+ Y V V G + ++ + P +R + N ++ W
Sbjct 250 SRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSAPPAPSNIRIANISANNDGTVNVMITW 309
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGN-------ETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
D + + + +Y +F+ + D L L ++ Y V +
Sbjct 310 DL--PEEPDIPVHHYKVFWSWTYSKYVIPAKKKRRKITDGPQNYVVLEGLQPNSNYNVEL 367
Query 593 AAYTDEG 599
A T G
Sbjct 368 QAVTRWG 374
Score = 74.9 bits (182), Expect = 2e-12, Method: Composition-based stats.
Identities = 80/505 (16%), Positives = 143/505 (28%), Gaps = 103/505 (20%)
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
N G N YK P P + E S L++ W++ S+ + Y +Q
Sbjct 160 NGCGHTCQVPKNL---YKGVPLKPRK-ELKFIELQSGDLEVKWSSKFNISIEPVIYVVQR 215
Query 262 R--------TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
R DA+ W + +T + D++ Y FR+ + G ++
Sbjct 216 RWNQGIHPSEDDATNWQTV----AQTTDERVQLSDIRASRWYQFRVAAVNVHGTRGFTAP 271
Query 314 SEEASGITYEDRPSKAPSFWYKIDPSHTQ-GYRTVQLVWKTLPPFEANGKILDYEVTLTR 372
S+ P APS + S G V + W P E + + Y+V +
Sbjct 272 SKHFRSSKDPSAP-PAPSNIRIANISANNDGTVNVMITWD--LPEEPDIPVHHYKVFWSW 328
Query 373 WKSH-----------LQNYTVNATKLTVNLTNDRYLATLTVRNLVG-------------- 407
S + + N L N Y L G
Sbjct 329 TYSKYVIPAKKKRRKITDGPQNYVVLEGLQPNSNYNVELQAVTRWGQIRLKSAKVSLHFS 388
Query 408 --------------KSDAAVLTIPACDFQATHPVMDLKA---FPKDNMLWVE--WTTPRE 448
+ + P FQ P LK F +DN L V+ W
Sbjct 389 TTQDNRNNNEQTSVEKPPKGVVDPYPTFQRRKPTRFLKIGTPFYQDNQLQVKIYWKKSGI 448
Query 449 SVKKYILEWCVLSDKAPCITDWQQEDG-TVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
++ ++ + + S ++ T + +L+ S Y +TV P +
Sbjct 449 NMNQFQVHSLLESCTHNDTKGLEKVTELTYENYMILKDLSFSCKYKVTVLPAKSKSRFKA 508
Query 508 ESIKAYLK-----------------QAPPSKGPTVRTKKVGKNEAVL---------EWDQ 541
ESI + P + + ++ W
Sbjct 509 ESIFFVTPPCSTFKEKTHKHINCAAEEVPVLPKVLAKPENLSASFIVQEGNITGHFSWK- 567
Query 542 LPVDVQNGFIRNYTIFYRTIIGNE-----------TAVNVDSSHTEYTLSSLTSDTLYMV 590
+ V + + + + + + + + + H T+ +L LY +
Sbjct 568 ISKAVLHQPMTGFQVTWAEVTTESRQNSLPNSIISQSQILPADHYVLTVPNLRPSMLYRL 627
Query 591 RMAAYTDEGGKDGPEFTFTTPKFAQ 615
+ T G F TP
Sbjct 628 EVQVLTTGGEGPATIKLFRTPDLPP 652
Score = 72.6 bits (176), Expect = 1e-11, Method: Composition-based stats.
Identities = 65/509 (13%), Positives = 124/509 (24%), Gaps = 87/509 (17%)
Query 107 TFGQLEQNVYGIT--IISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHL-ETNFTLKSE 163
+ + + G+P + K L I + + +W + + ++
Sbjct 157 CCSNGCGHTCQVPKNLYKGVPLKPRKELKFIELQSGDLEVKWSSKFNISIEPVIYVVQRR 216
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFVN------IEVWVEAENALGK----VTSDHIN 213
W + T V + + V A N G S H
Sbjct 217 WNQGIHPSEDDATNWQTVAQTTDERVQLSDIRASRWYQFRVAAVNVHGTRGFTAPSKHFR 276
Query 214 FDPVYKVKPNPPHNLSVINSEELSS---ILKLTWTNPSIKSVIILKYNIQY---RTKDAS 267
P P N+ + N + + +TW P + + Y + + +K
Sbjct 277 SSKDPSAPP-APSNIRIANISANNDGTVNVMITWDLPEEPDIPVHHYKVFWSWTYSKYVI 335
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVF---------RIR---CMKEDGKGYWSDWSE 315
+ + T ++ ++ L+P + Y +IR D
Sbjct 336 PAKKKRRKITDGPQNYVVLEGLQPNSNYNVELQAVTRWGQIRLKSAKVSLHFSTTQDNRN 395
Query 316 EASGITYEDRP------------SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI 363
+ E P K F P + V++ WK ++
Sbjct 396 NNEQTSVEKPPKGVVDPYPTFQRRKPTRFLKIGTPFYQDNQLQVKIYWKKSGINMNQFQV 455
Query 364 LDYEVTLTRWKSHLQNYTVNATKLTVNLTND---RYLATLTVRNLVGKSDAAVLTIPACD 420
+ T + T + D +TV KS +I
Sbjct 456 HSLLESCTHNDTKGLEKVTELTYENYMILKDLSFSCKYKVTVLPAKSKSRFKAESIFFVT 515
Query 421 FQ-------------------ATHPVMDLKAFPKDNMLWV---------EWTTPR----E 448
P + K V W + +
Sbjct 516 PPCSTFKEKTHKHINCAAEEVPVLPKVLAKPENLSASFIVQEGNITGHFSWKISKAVLHQ 575
Query 449 SVKKYILEWCVLSDKAP------CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD 502
+ + + W ++ ++ I Q H NL S Y + V +
Sbjct 576 PMTGFQVTWAEVTTESRQNSLPNSIISQSQILPADHYVLTVPNLRPSMLYRLEVQVLTTG 635
Query 503 GPGSPESIKAYLKQAPP--SKGPTVRTKK 529
G G PP P ++
Sbjct 636 GEGPATIKLFRTPDLPPFLPHRPHLKHHP 664
>sp|Q80W87|ROBO4_RAT Roundabout homolog 4 OS=Rattus norvegicus
OX=10116 GN=Robo4 PE=2 SV=1
Length=961
Score = 77.6 bits (189), Expect = 4e-13, Method: Composition-based stats.
Identities = 44/232 (19%), Positives = 71/232 (31%), Gaps = 23/232 (10%)
Query 393 NDRYLATLTVRNLVG--KSDAAVLTIPACDFQATH----------------PVMDLKAFP 434
ND N G +S AA ++I H +K
Sbjct 211 NDTGTYMCMATNNAGQRESRAARVSIQESPDHKEHLELLAVRIQLENVTLLNPEPVKGPK 270
Query 435 KDNMLWVEWTT--PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
+W+ W P + Y + D + W + G L + Y
Sbjct 271 PGPAVWLSWKVSGPAAPAQSYTALFRAQRDPRDQGSPWTEVLLDGLLNAKLGGLRWGQDY 330
Query 493 LITVTPVYADGPGSPESIKA-YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
V P G ++ L + PS P T + G + W P + NGFI
Sbjct 331 EFKVRPSSGRARGPDSNVLLLRLPEQVPSAPPQEVTLRPGNGSVFVSWAPPPAENHNGFI 390
Query 552 RNYTIF-YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
R Y ++ V T+ +++ + Y V++AA T G +
Sbjct 391 RGYQVWSLGNASLPAANWTVVGEQTQLEIAARMPGS-YCVQVAAVTGAGAGE 441
Score = 69.9 bits (169), Expect = 8e-11, Method: Composition-based stats.
Identities = 33/226 (15%), Positives = 63/226 (28%), Gaps = 27/226 (12%)
Query 227 NLSVINSEELSSILKLTWT---NPSIKSVIILKYNIQYRTKD-ASTWSQIPPEDTASTRS 282
N + + + L+W + + Q +D S W+++ + + +
Sbjct 262 NPEPVKGPKPGPAVWLSWKVSGPAAPAQSYTALFRAQRDPRDQGSPWTEVLLDGLLNAK- 320
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
+ L+ +Y F++R +G S E PS P + +
Sbjct 321 ---LGGLRWGQDYEFKVRPSSGRARGPD---SNVLLLRLPEQVPSAPPQ-----EVTLRP 369
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS----HLQNYTVNATKLTVNLTNDRYLA 398
G +V + W P NG I Y+V S + Y
Sbjct 370 GNGSVFVSWAPPPAENHNGFIRGYQVWSLGNASLPAANWTVVGEQTQLEIAARMPGSYCV 429
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWT 444
+ G + ++ + D V WT
Sbjct 430 QVAAVTGAGAGEPSIPVCLLLEQAMEQSARDPSKH-------VSWT 468
Score = 49.1 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 32/194 (16%), Positives = 50/194 (26%), Gaps = 30/194 (15%)
Query 326 PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT 385
P P+ W L WK P Y + +
Sbjct 269 PKPGPAVW---------------LSWKVSGPAAPA---QSYTALFRAQRDPRDQGSPWTE 310
Query 386 KLTVNLTN-------DRYLATLTVRNLVGK---SDAAVLTIPACDFQATHPVMDLKAFPK 435
L L N VR G+ D+ VL + + + P ++ P
Sbjct 311 VLLDGLLNAKLGGLRWGQDYEFKVRPSSGRARGPDSNVLLLRLPEQVPSAPPQEVTLRPG 370
Query 436 DNMLWVEWTTPR-ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
+ ++V W P E+ +I + V S + Y +
Sbjct 371 NGSVFVSWAPPPAENHNGFIRGYQVWSLGNASLPAANWTVVGEQTQLEIAARMPGS-YCV 429
Query 495 TVTPVYADGPGSPE 508
V V G G P
Sbjct 430 QVAAVTGAGAGEPS 443
>sp|Q12913|PTPRJ_HUMAN Receptor-type tyrosine-protein phosphatase
eta OS=Homo sapiens OX=9606 GN=PTPRJ PE=1 SV=3
Length=1337
Score = 77.6 bits (189), Expect = 4e-13, Method: Composition-based stats.
Identities = 70/431 (16%), Positives = 119/431 (28%), Gaps = 73/431 (17%)
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK 264
G +D + P+P ++ ++ + + LTW + + KY ++++ +
Sbjct 102 GSNGTDGASQKTPSSTGPSPVFDIKAVSI--SPTNVILTWKSNDTAASE-YKYVVKHKME 158
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 324
+ T T + + L+P T YVF I G W D I
Sbjct 159 NEKT-------ITVVHQPWCNITGLRPATSYVFSI--TPGIGNETWGDP----RVIKVIT 205
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA 384
P + G R L W A+ ++L + + VN
Sbjct 206 EPIPVSDLRVALT-----GVRKAALSWSNGNGT-ASCRVLLESIGSHEELTQDSRLQVNI 259
Query 385 TKLTVNLTNDRYLATLTVRNLVGK------SDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
+ L + + L G A T + T PV D
Sbjct 260 SGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSRAGSPTAPVHDESLVG---- 315
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
P + + L L Y TV
Sbjct 316 -------PVDPSSG---------------------QQSRDTEVLLVGLEPGTRYNATVYS 347
Query 499 VYADG-PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
A+G G P++I+ + V + L W D ++ Y I
Sbjct 348 QAANGTEGQPQAIEFRTNA---IQVFDVTAVNISATSLTLIWKV--SDNESSSNYTYKIH 402
Query 558 YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE--FTFTTPKFAQ 615
+ G + N++ S + L S T Y + + G +G TP
Sbjct 403 ---VAGETDSSNLNVSEPRAVIPGLRSSTFYNITVCPV--LGDIEGTPGFLQVHTPPVPV 457
Query 616 GEIEAIVVPVC 626
+ VV
Sbjct 458 SDFRVTVVSTT 468
Score = 76.8 bits (187), Expect = 6e-13, Method: Composition-based stats.
Identities = 71/431 (16%), Positives = 134/431 (31%), Gaps = 56/431 (13%)
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
T + + + G ++ + + P+ ++ V+ +
Sbjct 499 TTNQSIIIGGLFPGTKYCFEIVPKGPNG---TEGASRTVCNRTVPSAVFDIHVVYV--TT 553
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
+ + L W +P S + I+ S+ T++ + T+Q L P T Y
Sbjct 554 TEMWLDWKSPDGASEYVYHLVIE---------SKHGSNHTSTYDKAITLQGLIPGTLYNI 604
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT---L 354
I + W D + A PS ID S L W+
Sbjct 605 TISPEVDH---VWGDPNSTAQYT--------RPSNVSNIDVSTN--TTAATLSWQNFDDA 651
Query 355 PPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVL 414
P + +++ + + + + +T + Y + + G
Sbjct 652 SPTYSYCLLIEKAGNSSNATQVVTDIGITDATVTELIPGSSYTVEIFAQVGDGIKSLEPG 711
Query 415 TIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE-----WCVLSDKAPCITD 469
C A+ D + PK+ L ++WT P + + LE W + C +
Sbjct 712 RKSFCTDPASMASFDCEVVPKEPALVLKWTCPPGANAGFELEVSSGAWNNATHLESCSS- 770
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES---IKAYLKQAPPSKGPTVR 526
E+GT +RT + L S Y I++T V +P PP P +
Sbjct 771 ---ENGTEYRTEV-TYLNFSTSYNISITTVSCGKMAAPTRNTCTTGITDPPPPDGSPNIT 826
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSD- 585
V N +++ G I+ Y + T + +V +YT
Sbjct 827 --SVSHNSVKVKFSGFEASH--GPIKAYAVILTTGEAGHPSADV----LKYTYEDFKKGA 878
Query 586 ----TLYMVRM 592
Y++R
Sbjct 879 SDTYVTYLIRT 889
Score = 76.4 bits (186), Expect = 9e-13, Method: Composition-based stats.
Identities = 85/499 (17%), Positives = 140/499 (28%), Gaps = 98/499 (20%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P ++ + + W E + +K + K + P
Sbjct 119 PSPVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQ---PWCNITG 175
Query 186 YSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ + +G T D +P P +L V + + L+W
Sbjct 176 LRPA--TSYVFSITP--GIGNETWGDPRVIKV--ITEPIPVSDLRVALTGVRKAA--LSW 227
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR---IRC 301
+N + + + + + E T +R + LKP +Y ++
Sbjct 228 SNGNGTAS----CRVLLESIGS------HEELTQDSRLQVNISGLKPGVQYNINPYLLQS 277
Query 302 MKEDGK------GYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR--TVQLVWKT 353
K G G + +E + + P S +DPS Q R V LV
Sbjct 278 NKTKGDPLGTEGGLDASNTERSRAGSP-TAPVHDESLVGPVDPSSGQQSRDTEVLLV--- 333
Query 354 LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAV 413
Y T+ S N T + TN + +T N+
Sbjct 334 -----GLEPGTRYNATVY---SQAANGTEGQPQAIEFRTNAIQVFDVTAVNI-------- 377
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWT-TPRESVKKYILEWCVLSDKAPCITDWQQ 472
L + W + ES Y + + TD
Sbjct 378 ---------------------SATSLTLIWKVSDNESSSNY--TYKIHVAGE---TDSSN 411
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLK-QAPPSKGPTVRTKKVG 531
+ + R + G L S Y ITV PV D G+P +L+ PP R V
Sbjct 412 LNVSEPRAVIPG-LRSSTFYNITVCPVLGDIEGTP----GFLQVHTPPVPVSDFRVTVVS 466
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
E L W + I + GN V + ++ + L T Y
Sbjct 467 TTEIGLAWSSHDAESFQMHIT------QEGAGNSR-VEITTNQ-SIIIGGLFPGTKYCFE 518
Query 592 MAAYTDEGGKDGPEFTFTT 610
+ G +G E T
Sbjct 519 IVPK----GPNGTEGASRT 533
Score = 61.0 bits (146), Expect = 5e-08, Method: Composition-based stats.
Identities = 71/484 (15%), Positives = 141/484 (29%), Gaps = 48/484 (10%)
Query 131 NLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY 190
+++ + + W + +N+T K A P + +
Sbjct 371 DVTAVNISATSLTLIWK-VSDNESSSNYTYKIHVAGET-DSSNLNVSEPRAVIPGLRSST 428
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
F + V LG + P P + V ++ + L W++ +
Sbjct 429 F--YNITVCPV--LGDIEGTPGFLQV--HTPPVPVSDFRVTVV--STTEIGLAWSSHDAE 480
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
S + + T++ + S++ +T S + L P T+Y F I +G
Sbjct 481 S-----FQMHI-TQEGAGNSRVEI----TTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGA 530
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
S + PS + + L WK P A+ + +
Sbjct 531 S------RTVCNRTVPSAVFDIHVVYVTTTE-----MWLDWK--SPDGASEYVYHLVIES 577
Query 371 TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
+H Y T L + Y T++ D + V ++
Sbjct 578 KHGSNHTSTYDKAIT-LQGLIPGTLYNITISPEVDHVWGDPN----STAQYTRPSNVSNI 632
Query 431 KAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT-YLRGNLAES 489
+ W ++ Y +C+L +KA ++ Q + T L
Sbjct 633 DVSTNTTAATLSWQNFDDASPTY--SYCLLIEKAGNSSNATQVVTDIGITDATVTELIPG 690
Query 490 KCYLITVTPVYADGPGSPESIK--AYLKQAPPSKGPTVRTKKVGKN-EAVLEWDQLPVDV 546
Y + + DG S E + P+ + + V K VL+W P
Sbjct 691 SSYTVEIFAQVGDGIKSLEPGRKSFCTD---PASMASFDCEVVPKEPALVLKWTCPPGAN 747
Query 547 QNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
+ + + E+ + + + ++ L T Y + + G P
Sbjct 748 AGFELEVSSGAWNNATHLESCSSENGTEYRTEVTYLNFSTSYNISIT-TVSCGKMAAPTR 806
Query 607 TFTT 610
T
Sbjct 807 NTCT 810
Score = 41.8 bits (96), Expect = 0.043, Method: Composition-based stats.
Identities = 45/295 (15%), Positives = 91/295 (31%), Gaps = 21/295 (7%)
Query 128 KPKNLSCI--VNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
+P N+S I W + ++ L E A + + D +
Sbjct 625 RPSNVSNIDVSTNTTAATLSWQNFDDASPTYSYCLLIEKAGNSSNATQVVTDIGITDATV 684
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ + V + A+ G + + + V+ E L L WT
Sbjct 685 TELIPGSSYTVEIFAQVGDGIKSLEPGRKSFCTDPASMASFDCEVVPKE---PALVLKWT 741
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA-STRSSFTVQDLKPFTEYVFRIRCMKE 304
P + ++ + + + + + T V L T Y I +
Sbjct 742 CP---PGANAGFELEVSSGAWNNATHLESCSSENGTEYRTEVTYLNFSTSYNISITTV-S 797
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
GK + +GIT P +P+ + + +V++ + ++G I
Sbjct 798 CGKMAAPTRNTCTTGITDPPPPDGSPNI-------TSVSHNSVKVKFSGF--EASHGPIK 848
Query 365 DYEVTLTRWKSHLQNYTV--NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
Y V LT ++ + V + +D Y+ L G+S + +
Sbjct 849 AYAVILTTGEAGHPSADVLKYTYEDFKKGASDTYVTYLIRTEEKGRSQSLSEVLK 903
>sp|O88786|I13R2_MOUSE Interleukin-13 receptor subunit alpha-2
OS=Mus musculus OX=10090 GN=Il13ra2 PE=1 SV=1
Length=383
Score = 75.7 bits (184), Expect = 5e-13, Method: Composition-based stats.
Identities = 36/182 (20%), Positives = 67/182 (37%), Gaps = 14/182 (8%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWAT----HKFADCKAKRDTPTSCTV- 184
+++ CI + + C W G+ + +TN+T+ + + AD + C +
Sbjct 135 QDMKCIYYNWQYLVCSWKPGKTVYSDTNYTMFFWYEGLDHALQCADYLQHDEKNVGCKLS 194
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ + + + + V + L + S + F VKP PP L + + +++ W
Sbjct 195 NLDSSDYKDFFICVNGSSKLEPIRSSYTVFQLQNIVKPLPPEFLHISVENSID--IRMKW 252
Query 245 TNPSIKSVIILK-YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
+ P Y I R D S S D R + +DL F +RC
Sbjct 253 STPGGPIPPRCYTYEIVIREDDISWESATDKNDMKLKRRANESEDL------CFFVRCKV 306
Query 304 ED 305
Sbjct 307 NI 308
Score = 64.5 bits (155), Expect = 2e-09, Method: Composition-based stats.
Identities = 50/296 (17%), Positives = 93/296 (31%), Gaps = 34/296 (11%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNP---SIKSVIILKYNIQYRTKDASTWSQIPPED 276
+K NPP + +++ L L L W P L+Y ++YR D+ +W I +
Sbjct 24 IKVNPPQDFEILD-PGLLGYLYLQWKPPVVIEKFKGCTLEYELKYRNVDSDSWKTIITRN 82
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKE--DGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
DL E R + +G S W E + GI+ E
Sbjct 83 LIYKDG----FDLNKGIEGKIRTHLSEHCTNGSEVQSPWIEASYGISDEGSLETKIQDMK 138
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--------RWKSHLQNYTVNATK 386
I + + WK ++ +Y + + +LQ+ N
Sbjct 139 CIYYNWQ----YLVCSWKPGKTVYSD---TNYTMFFWYEGLDHALQCADYLQHDEKNVGC 191
Query 387 LTVNLTNDRYLATLTVRNLVGK-----SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWV 441
NL + Y N K S V + + + + + +
Sbjct 192 KLSNLDSSDYKDFFICVNGSSKLEPIRSSYTVFQLQNIVKPLPPEFLHISVENSID-IRM 250
Query 442 EWTTPRESVKKYILEWCVLSDKAPCITDWQQ-EDGTVHRTYLRGNLAESKCYLITV 496
+W+TP + + ++ + W+ D + R N +E C+ +
Sbjct 251 KWSTPGGPIPPRCYTYEIVIRED--DISWESATDKNDMKLKRRANESEDLCFFVRC 304
>sp|O02466|ILPR_BRALA Insulin-like peptide receptor OS=Branchiostoma
lanceolatum OX=7740 PE=2 SV=1
Length=1363
Score = 77.6 bits (189), Expect = 5e-13, Method: Composition-based stats.
Identities = 33/169 (20%), Positives = 62/169 (37%), Gaps = 24/169 (14%)
Query 226 HNLSVINSEELSSILKLTWT---NPSIKSVIILKYNIQYRT-----------KDASTWSQ 271
L + ++ L W+ P + +L Y + YR +DA ++
Sbjct 475 SRLEIEEINTSKDMIILRWSEFRPPDPRD--LLSYTVSYRETEDQGIDEYDGQDACGNTE 532
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS-DWSEEASGITYEDRPSKAP 330
D + T+++ + LKP+T+Y ++ + G S S+ T D+P+
Sbjct 533 WKEFDVSPTQTAHIITGLKPWTQYALLVKTYTKAGAREGSGAKSDIVYARTDADKPTHPQ 592
Query 331 SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN 379
+ T+ + WK PP NG + Y V R + +
Sbjct 593 DVVVY-----SNSSNTLIITWK--PPNRPNGNVTHYIVKYKRQQEDVAE 634
Score = 75.7 bits (184), Expect = 1e-12, Method: Composition-based stats.
Identities = 25/171 (15%), Positives = 52/171 (30%), Gaps = 25/171 (15%)
Query 435 KDNMLWVEWT----TPRESVKKYILEWCV---------LSDKAPCITDWQQEDGTVHRT- 480
+M+ + W+ + Y + + A T+W++ D + +T
Sbjct 485 SKDMIILRWSEFRPPDPRDLLSYTVSYRETEDQGIDEYDGQDACGNTEWKEFDVSPTQTA 544
Query 481 YLRGNLAESKCYLITVTPVYADG-----PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
++ L Y + V G + + A P+ V N
Sbjct 545 HIITGLKPWTQYALLVKTYTKAGAREGSGAKSDIVYARTDADKPTHPQDVVVYSNSSNTL 604
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDT 586
++ W P + NG + +Y + Y+ + + EY L
Sbjct 605 IITWK--PPNRPNGNVTHYIVKYKRQQEDVAEM----EQREYCKGGLKPHR 649
Score = 68.0 bits (164), Expect = 4e-10, Method: Composition-based stats.
Identities = 35/195 (18%), Positives = 60/195 (31%), Gaps = 35/195 (18%)
Query 481 YLRGNLAESKCYLITVTPVYAD---GPGSPESIKAYLK--QAPPSKGPTVRTKKVGKNEA 535
+ L Y+I V AD G A + + + + ++ ++ A
Sbjct 768 VVLTGLRHFSEYIIEVIACNADAAVGCSGSAVELARTQADDSADNIPGNITVVEIKEDMA 827
Query 536 VLEWDQLPVDVQNGFIRNYTIFYR---------TIIGNETAVNVDSSHTEYTLSSLTSDT 586
L W D N + +Y I Y+ YT+S+L
Sbjct 828 KLYW--PKPDSPNSMVVHYNIEYKKLGSDFNYEQQEPKCVENFKFLQSQGYTISNLV-AG 884
Query 587 LYMVRMAAYTDEGGKDGPEFTFTT---------PKFAQGEIEAIVVPV-------CLAFL 630
Y VR A + G +G + T P + + V + L +
Sbjct 885 NYSVRFRATSFAG--NGSWSNYVTFYVEEEDTSPDPQDPQQQVPVSLMIGMGVGFSLLLI 942
Query 631 LTTLLGVLFCFNKRD 645
L + G+ +C KR
Sbjct 943 LAVIFGIWYCTKKRF 957
Score = 65.3 bits (157), Expect = 3e-09, Method: Composition-based stats.
Identities = 29/172 (17%), Positives = 56/172 (33%), Gaps = 27/172 (16%)
Query 457 WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ + + + DW + D T+ L + C + +T V D G PE
Sbjct 404 YVLDNRNLEKLFDWDRTDITIDEGKLFFHFNPKLCRHVILTMV--DKVGLPEHAITDTDI 461
Query 517 APPSKGPTVRT---------KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII----- 562
+ + G + K+ +L W + + +YT+ YR
Sbjct 462 STLTNGDQAQCSFSRLEIEEINTSKDMIILRWSEFRPPDPR-DLLSYTVSYRETEDQGID 520
Query 563 ----------GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP 604
+V + T + ++ L T Y + + YT G ++G
Sbjct 521 EYDGQDACGNTEWKEFDVSPTQTAHIITGLKPWTQYALLVKTYTKAGAREGS 572
Score = 64.9 bits (156), Expect = 4e-09, Method: Composition-based stats.
Identities = 34/158 (22%), Positives = 61/158 (39%), Gaps = 15/158 (9%)
Query 190 YFVNIEVWVEAENA---LG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+F + V A NA +G ++ + N P N++V E + KL W
Sbjct 775 HFSEYIIEVIACNADAAVGCSGSAVELARTQADDSADNIPGNITV--VEIKEDMAKLYWP 832
Query 246 NPSIKSVIILKYNIQYRTKDAS-TWSQIPPEDTAS----TRSSFTVQDLKPFTEYVFRIR 300
P + +++ YNI+Y+ + + Q P+ + +T+ +L Y R R
Sbjct 833 KPDSPNSMVVHYNIEYKKLGSDFNYEQQEPKCVENFKFLQSQGYTISNLVAG-NYSVRFR 891
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
G G WS++ + E+ S P + P
Sbjct 892 ATSFAGNGSWSNY---VTFYVEEEDTSPDPQDPQQQVP 926
Score = 50.2 bits (118), Expect = 9e-05, Method: Composition-based stats.
Identities = 24/172 (14%), Positives = 50/172 (29%), Gaps = 37/172 (22%)
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWK---------------SHLQNYTVNATKLTVNL 391
+ L W P + +L Y V+ + + + + V+ T+ +
Sbjct 489 IILRWSEFRPPDPR-DLLSYTVSYRETEDQGIDEYDGQDACGNTEWKEFDVSPTQTAHII 547
Query 392 TN----DRYLATLTVRNLVGK-----SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE 442
T +Y + G + + ++ + THP + N L +
Sbjct 548 TGLKPWTQYALLVKTYTKAGAREGSGAKSDIVYARTDADKPTHPQDVVVYSNSSNTLIIT 607
Query 443 WTTPRESVKK---YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
W P YI+++ + R Y +G L +
Sbjct 608 WKPPNRPNGNVTHYIVKYKRQQED---------VAEMEQREYCKGGLKPHRP 650
Score = 46.4 bits (108), Expect = 0.002, Method: Composition-based stats.
Identities = 25/177 (14%), Positives = 50/177 (28%), Gaps = 30/177 (17%)
Query 135 IVNEGKKMR-CEWD--GGRETHLETNFTLKSEWATHKFAD-------CKAKRDTPTSCTV 184
+N K M W + ++T+ + D C +
Sbjct 481 EINTSKDMIILRWSEFRPPDPRDLLSYTVSYRETEDQGIDEYDGQDACGNTEWKEFDVSP 540
Query 185 DYSTVYFVNIEVWVE----------AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
+ ++ W + A G I + KP P ++ V
Sbjct 541 TQTAHIITGLKPWTQYALLVKTYTKAGAREGSGAKSDIVYARTDADKPTHPQDVVV--YS 598
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
S+ L +TW P+ + + Y ++Y+ + + + LKP
Sbjct 599 NSSNTLIITWKPPNRPNGNVTHYIVKYKRQQEDV--------AEMEQREYCKGGLKP 647
Score = 40.6 bits (93), Expect = 0.080, Method: Composition-based stats.
Identities = 23/164 (14%), Positives = 43/164 (26%), Gaps = 18/164 (11%)
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
E T + L+ F+EY+ + D S + E + +D P
Sbjct 759 ETTVWNEHMVVLTGLRHFSEYIIEVIACNADAAVGCSGSAVELARTQADDSADNIPGNIT 818
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ------------NYTV 382
++ L W P N ++ Y + + S +
Sbjct 819 VVEIKEDMAK----LYW--PKPDSPNSMVVHYNIEYKKLGSDFNYEQQEPKCVENFKFLQ 872
Query 383 NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
+ NL Y + G + + + T P
Sbjct 873 SQGYTISNLVAGNYSVRFRATSFAGNGSWSNYVTFYVEEEDTSP 916
>sp|A1L4K1|FSD2_HUMAN Fibronectin type III and SPRY domain-containing
protein 2 OS=Homo sapiens OX=9606 GN=FSD2 PE=1 SV=1
Length=749
Score = 76.4 bits (186), Expect = 7e-13, Method: Composition-based stats.
Identities = 34/195 (17%), Positives = 65/195 (33%), Gaps = 15/195 (8%)
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK-YILEWCVLSDKAPCITD 469
++ TIPA +P + + + V W+ + + Y L + + D +P
Sbjct 364 GSINTIPAPSAPVINPQ--VPNSATGSSVRVCWSLYSDDTVESYQLSYRPVQDSSPGTDQ 421
Query 470 WQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKK 529
+ NL + Y VT GP Y+ PS P ++TK+
Sbjct 422 AEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSERAVYM--TAPS-PPIIKTKE 478
Query 530 VGK--NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYTLSSLTS 584
+ ++ W+ + +YT+ E +V T ++ L
Sbjct 479 IRSCEEAVLICWE----SGNLNPVDSYTVELTQAESPEASGVTESVVGIPTCESVVQLQP 534
Query 585 DTLYMVRMAAYTDEG 599
Y++ + A G
Sbjct 535 GRSYIIYVRALNMGG 549
Score = 74.9 bits (182), Expect = 2e-12, Method: Composition-based stats.
Identities = 39/199 (20%), Positives = 67/199 (34%), Gaps = 24/199 (12%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
P+ P + + S +++ W+ S +V Y + YR S+ E T
Sbjct 369 IPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVE--SYQLSYRPVQDSSPGTDQAEFTV 426
Query 279 STRSSF-TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
+ + ++ +V +L P T+Y F + G S SE A +T PS +I
Sbjct 427 TVKETYCSVTNLVPNTQYEFWVTAHNRAG---PSPSSERAVYMT---APSPPIIKTKEIR 480
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT----RWKSHLQNYTVNATKLTV---N 390
V + W++ + Y V LT S + V
Sbjct 481 SC----EEAVLICWESGNLN----PVDSYTVELTQAESPEASGVTESVVGIPTCESVVQL 532
Query 391 LTNDRYLATLTVRNLVGKS 409
Y+ + N+ G S
Sbjct 533 QPGRSYIIYVRALNMGGPS 551
Score = 70.7 bits (171), Expect = 4e-11, Method: Composition-based stats.
Identities = 40/202 (20%), Positives = 67/202 (33%), Gaps = 18/202 (9%)
Query 126 PEKPK-NLSC-IVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDT----P 179
P P N G +R W + +E ++ L T
Sbjct 372 PSAPVINPQVPNSATGSSVRVCWSLYSDDTVE-SYQLSYRPVQDSSPGTDQAEFTVTVKE 430
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
T C+V + V E WV A N G S VY P+PP +
Sbjct 431 TYCSVT-NLVPNTQYEFWVTAHNRAGPSPSSE---RAVYMTAPSPPI-IKTKEIRSCEEA 485
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ + W + ++ + Y ++ ++ S + E + +V L+P Y+ +
Sbjct 486 VLICWESGNLN--PVDSYTVELTQAESPEASGV-TESVVGIPTCESVVQLQPGRSYIIYV 542
Query 300 RCMKEDGKGYWSDWSEEASGIT 321
R + G S SE A+ T
Sbjct 543 RALN---MGGPSVRSEPATVHT 561
Score = 64.1 bits (154), Expect = 4e-09, Method: Composition-based stats.
Identities = 42/281 (15%), Positives = 89/281 (32%), Gaps = 46/281 (16%)
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--- 565
SI + P P V + + W D + +Y + YR + +
Sbjct 365 SINTIPAPSAPVINPQVP-NSATGSSVRVCWSLYSDDT----VESYQLSYRPVQDSSPGT 419
Query 566 --TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
V T ++++L +T Y + A+ G E + I+ +
Sbjct 420 DQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSERAVYMTAPSPPIIKTKEI 479
Query 624 PVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMY 683
C VL C+ +L +P S+ + + P + ++ +
Sbjct 480 RSC-------EEAVLICWESGNL----------NPVDSYTVELTQAESPEASGVTESVV- 521
Query 684 SDGNFTDVSVVEIEANDKKPFPEDLKSL----DLFKKEKINTEGHSSGIGGSSCMSSSRP 739
G T SVV+++ ++ + ++T G + +C P
Sbjct 522 --GIPTCESVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGSYFRLNKDTC----HP 575
Query 740 SISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS 780
++ S++ ++ + + R PS F+R
Sbjct 576 WLTISEDGLTAVRSERR--------TPARELSPSDTHFTRC 608
Score = 56.8 bits (135), Expect = 9e-07, Method: Composition-based stats.
Identities = 32/190 (17%), Positives = 64/190 (34%), Gaps = 22/190 (12%)
Query 328 KAPSFWYKIDPS--HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ------- 378
APS I+P ++ +V++ W + Y+++ +
Sbjct 370 PAPSA-PVINPQVPNSATGSSVRVCWSLYSDDT----VESYQLSYRPVQDSSPGTDQAEF 424
Query 379 NYTVNATKLTV--NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
TV T +V + N +Y +T N G S ++ + + + + +
Sbjct 425 TVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSERAVY-MTAPSPPIIKTKEIRSCE 483
Query 437 NMLWVEWTT-PRESVKKYILEWCVL-SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
+ + W + V Y +E S +A +T+ T L + Y+I
Sbjct 484 EAVLICWESGNLNPVDSYTVELTQAESPEASGVTESVVGIPTCESVVQ---LQPGRSYII 540
Query 495 TVTPVYADGP 504
V + GP
Sbjct 541 YVRALNMGGP 550
>sp|Q5VTL7|FNDC7_HUMAN Fibronectin type III domain-containing
protein 7 OS=Homo sapiens OX=9606 GN=FNDC7 PE=2 SV=3
Length=733
Score = 76.0 bits (185), Expect = 8e-13, Method: Composition-based stats.
Identities = 51/301 (17%), Positives = 104/301 (35%), Gaps = 28/301 (9%)
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKL 387
AP ID ++++ ++ + W T+P Y +T + ++ TV +
Sbjct 27 SAPEI-PTIDQAYSKLSNSITVEWATVPGA------TSYLLTAEDGDTVIET-TVANSPG 78
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
TV +T+R++ + P++++ + P + + V+W
Sbjct 79 TVTGLKAATWYEITIRSISAAGRSQASPPKQAKTVLAAPILEVSS-PSSDSILVQW---- 133
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
E+V I + + W++ T + + +L Y I A+ P
Sbjct 134 EAVYMAIAFSVSIMRANGLGSIWKEN--TTNTSLTFTSLEAGTLYTIKAYAWNANRI--P 189
Query 508 ESIKAYLKQAPPSKGPTVRTK-KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET 566
++ P ++ G +A W G NYT+ + + +
Sbjct 190 GDDSTCNQRTSPRAPANIQVSFDSGALKASFSW-----ARAEG-AFNYTV---MALSDSS 240
Query 567 AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF-TFTTPKFAQGEIEAIVVPV 625
+ ++ + T+SSL T Y++ + A D G T T A G + P
Sbjct 241 ELTCSTTFSSCTISSLQCGTEYLISVLASNDAGSSKSSSAMTLKTVACAPGRVTIQEDPP 300
Query 626 C 626
Sbjct 301 G 301
Score = 75.7 bits (184), Expect = 1e-12, Method: Composition-based stats.
Identities = 66/420 (16%), Positives = 118/420 (28%), Gaps = 59/420 (14%)
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTW-TNPSIKSVIILKYNIQYRTKDASTWS 270
I V K P +LS+ + + W T P S ++ +D T
Sbjct 17 ICLKMVASAKSAPEIPTIDQAYSKLSNSITVEWATVPGATSYLLT-------AEDGDTVI 69
Query 271 QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
+ ++ T V LK T Y IR + G+ S S T P
Sbjct 70 ETTVANSPGT-----VTGLKAATWYEITIRSISAAGR---SQASPPKQAKTVLAAP---- 117
Query 331 SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN 390
I + ++ + W+ + A + + T LT
Sbjct 118 -----ILEVSSPSSDSILVQWEAVYMAIA----FSVSIMRANGLGSIWKENTTNTSLTFT 168
Query 391 LTNDRYLATLTVR----NLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
L T+ N + D + + + + W
Sbjct 169 SLEAGTLYTIKAYAWNANRI-PGDDSTCNQRTSPRAPANIQVSFDSGALKASF--SWARA 225
Query 447 RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
+ ++ LSD + T + +L YLI+V G S
Sbjct 226 EGAFNYTVM---ALSDSSELTC------STTFSSCTISSLQCGTEYLISVLASNDAG--S 274
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET 566
+S A + V ++ + W + + Y +F ++ G E
Sbjct 275 SKSSSAMTLKTVACAPGRVTIQEDPPGHLSVAWSSVDLGD------YYVVFVKSDDGLEV 328
Query 567 AVNVDSSHTEYTLSSLTS-DTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQGEIEAIVVP 624
N + + L+ Y + + Y G G F +TT +I ++V
Sbjct 329 HCNTSLTQCNF----LSECGFTYFISVFVYNKAGQSPLGDIFNYTTAPCCPSDINPVLVS 384
Score = 63.3 bits (152), Expect = 7e-09, Method: Composition-based stats.
Identities = 68/521 (13%), Positives = 146/521 (28%), Gaps = 69/521 (13%)
Query 83 NRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKM 142
N T +S+TFT + + + T + T P P N+ + + +
Sbjct 159 NTTNTSLTFTSLEAGTL-YTIKAYAWNANRIPGDDSTCNQRTSPRAPANIQ-VSFDSGAL 216
Query 143 --RCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
W E N+T+ + + + T +SCT+ + V A
Sbjct 217 KASFSWAR-AEGAF--NYTVMALSDSSELTCST----TFSSCTISSLQCG-TEYLISVLA 268
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQ 260
N G S P V E+ L + W++ + Y +
Sbjct 269 SNDAGSSKSSSAMTLKTVACAPG-----RVTIQEDPPGHLSVAWSSVDLGDY----YVVF 319
Query 261 YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
++ D ++ + + Y + + G+ D +
Sbjct 320 VKSDDGLE------VHCNTSLTQCNFLS-ECGFTYFISVFVYNKAGQSPLGDIFNYTT-- 370
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG--KILDYEVTLTRWKSHLQ 378
AP I+P R V++VW + E + Y + +
Sbjct 371 --------APCCPSDINPVLVSSDR-VEIVWSPVRGAELYETKAVDGYNMVECNDTTP-- 419
Query 379 NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
+ L + +Y T+ N V S+ + + + ++ + +M
Sbjct 420 --ACTLSALECD---TKYNITVYSFNEVRGSNMSCTPQFITTAPCSPEIKNV-SRDAFSM 473
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP 498
+ V W + + + V + + + + L +VT
Sbjct 474 INVHWRSTNDDAT-----YTVTAQGEKGLYQ----CSSTGESCTMRGLPCGSV--FSVTA 522
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
V G + + P + ++ ++ + W V + +
Sbjct 523 VAETQAGRSLPSYSVPLETVPCCPTGLTVTQITQSVINVSWTIGRVAQ-----THVAVLE 577
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
++ + L +T Y V + A + G
Sbjct 578 SHTGQSKCHTH----QNHCLLGCITCGINYTVTLKAISATG 614
Score = 40.6 bits (93), Expect = 0.076, Method: Composition-based stats.
Identities = 18/133 (14%), Positives = 46/133 (35%), Gaps = 21/133 (16%)
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSS 573
++ P + N +EW +P +Y + T +T + +
Sbjct 24 SAKSAPEIPTIDQAYSKLSNSITVEWATVPG------ATSYLL---TAEDGDTVIETTVA 74
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKD------------GPEFTFTTPKFAQGEIEAI 621
++ T++ L + T Y + + + + G P ++P ++
Sbjct 75 NSPGTVTGLKAATWYEITIRSISAAGRSQASPPKQAKTVLAAPILEVSSPSSDSILVQWE 134
Query 622 VVPVCLAFLLTTL 634
V + +AF ++ +
Sbjct 135 AVYMAIAFSVSIM 147
>sp|Q64612|PTPRV_RAT Receptor-type tyrosine-protein phosphatase
V OS=Rattus norvegicus OX=10116 GN=Ptprv PE=1 SV=1
Length=1711
Score = 76.4 bits (186), Expect = 1e-12, Method: Composition-based stats.
Identities = 53/326 (16%), Positives = 85/326 (26%), Gaps = 37/326 (11%)
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
S + L P Y I D S+ SG T P
Sbjct 433 SVPSGATHVIFCGLVPGAHYRVDIASST-------GDISQSISGYTSPLPPQS------- 478
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ-----NYTVNATKLTVN 390
++ + + W P G++ Y+VT + S + + LT+
Sbjct 479 LEVISRSSPSDLTIAWGPAP-----GQLEGYKVTWHQDGSQRSPGDLVDLGPDTLSLTLK 533
Query 391 LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV 450
T++ G D+ I +C A + L + L W P
Sbjct 534 SLVPGSCYTVSAWAWAGNLDSDSQKIHSCTRPAPPTNLSLGFAHQPAALKASWYHPPGGR 593
Query 451 KKYILE-WCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES 509
+ L + + +E L V G S
Sbjct 594 DAFHLRLYRLRPLTLESEKVLPREAQNFSWAQLTAGC------EFQVQLSTLWGSERSSS 647
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
A PPS V + + W +P G R Y+ T++
Sbjct 648 ANA-TGWTPPSAPTLVNVTSDAPTQLQVSWAHVP----GGRSRYQVTLYQESTRTATSIM 702
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAY 595
L LT T Y V + ++
Sbjct 703 GPKEDGTSFL-GLTPGTKYKVEVISW 727
Score = 71.8 bits (174), Expect = 2e-11, Method: Composition-based stats.
Identities = 71/477 (15%), Positives = 135/477 (28%), Gaps = 45/477 (9%)
Query 122 SGL-PPEKPKNLSCIVNE-GKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTP 179
SG P P++L I + W LE + + +
Sbjct 468 SGYTSPLPPQSLEVISRSSPSDLTIAWGP-APGQLEGYKVTWHQDGSQRSPGDLVDLGPD 526
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSI 239
T S V V A G + SD + P PP NLS+ + + +
Sbjct 527 TLSLTLKSLVPGSCYTVSAWAW--AGNLDSDSQKIHSCTR--PAPPTNLSLGFAHQ-PAA 581
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
LK +W +P + R + +P E + + T F++
Sbjct 582 LKASWYHPPGGRDAFHLRLYRLRPLTLESEKVLPREAQNFSWAQLTAGC-------EFQV 634
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA 359
+ G S+ S A+ + P AP+ + TQ +Q+ W +P +
Sbjct 635 QLSTLWG----SERSSSANATGW--TPPSAPTLVNVTSDAPTQ----LQVSWAHVPGGRS 684
Query 360 NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
++ Y+ + S + + T +Y + G A + A
Sbjct 685 RYQVTLYQESTRTATSIMGPK-EDGTSFLGLTPGTKYKVEVISW--AGPLYTAAANVSAW 741
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ + + ++ + W P + C W+Q
Sbjct 742 TYPLIPNELLVSMQAGSAVVNLAW--PSGPLG---QGACHAQLSDAGHLSWEQPLKLGQE 796
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
++ +L ++V S + ++ P V L W
Sbjct 797 LFMLRDLTPGHTISMSVRCRAGPLQASTHLVVLSVE---PGPVEDVLC-HPEATYLALNW 852
Query 540 DQLPVDVQNGFIRNYTIFYR---TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
+ G + + G V++S L +L T Y + +
Sbjct 853 -----TMPAGDVDVCLVVVERLVPGGGTHFVFQVNTSGDALLLPNLMPTTSYRLSLT 904
Score = 55.2 bits (131), Expect = 3e-06, Method: Composition-based stats.
Identities = 57/398 (14%), Positives = 109/398 (27%), Gaps = 64/398 (16%)
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT--NPSIKSVIILKYNIQYRTKDAS 267
++ + P L + +S + L+ +W+ S +L Y+++
Sbjct 116 QNVTITLTARTAPTVVRGLQL-HSAGSPARLEASWSDAPGDQDSYQLLLYHLE------- 167
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS--DWSEEASGITYEDR 325
+ + + S++ DL P T+YV + S W+E
Sbjct 168 SQTLACNVSVSPDTLSYSFGDLLPGTQYVLEVITWAGSLHAKTSILQWTEPV-------- 219
Query 326 PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ-----NY 380
P G ++Q W + G + + LT
Sbjct 220 ---PPDHLAL----RALGTSSLQAFW-----NSSEGA-TSFHLMLTDLLGGTNTTAVIRQ 266
Query 381 TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW 440
V+ + + + A ++ DL P N LW
Sbjct 267 GVSTHTFLHLSPGTPHELKICA----SAGPHQIWGPSATEWTYPSYPSDLVLTPLRNELW 322
Query 441 VEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY 500
W + Y+L+ + + G L Y + + +
Sbjct 323 ASWKAGLGARDGYVLKLSGPMESTSTLG------PEECNAVFPGPLPPG-HYTLQLKVLA 375
Query 501 ADGPGSPESIKAYLKQAP--PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
+ +L ++ P + P R D L Q G R ++
Sbjct 376 G-PYDAWVEGSTWLAESAALPREVPGARLWL----------DGLEASKQPG--RRALLYS 422
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYT 596
G+ ++V S T L Y V +A+ T
Sbjct 423 DDAPGSLGNISVPSGATHVIFCGLVPGAHYRVDIASST 460
Score = 41.0 bits (94), Expect = 0.073, Method: Composition-based stats.
Identities = 63/449 (14%), Positives = 125/449 (28%), Gaps = 66/449 (15%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWD---GGRETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
PP P ++ + +++ W GGR + T + + AT +
Sbjct 655 PPSAPTLVNVTSDAPTQLQVSWAHVPGGRSRYQVTLYQESTRTATSIMGPKEDGTSF--- 711
Query 182 CTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
+ VE + G + + N P P+ L V S+++
Sbjct 712 ------LGLTPGTKYKVEVISWAGPLYTAAANVSAW--TYPLIPNELLVSMQAG-SAVVN 762
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
L W + + + Q +W Q + F ++DL P +RC
Sbjct 763 LAWPSGPLGQG---ACHAQLSDAGHLSWEQ----PLKLGQELFMLRDLTPGHTISMSVRC 815
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV--QLVWKTLPPFEA 359
+ ED + + ++ + G V +V + +P
Sbjct 816 RAGPLQASTHLVVLSVEPGPVEDVLCHPEATYLALNWTMPAGDVDVCLVVVERLVPGG-- 873
Query 360 NGKILDYEVTLTRWKSHLQNYTVNAT---KLTVNLTNDRYLATLTVRNLVGKS---DAAV 413
G ++V + L N + LTV N R+ +++ +
Sbjct 874 -GTHFVFQVNTSGDALLLPNLMPTTSYRLSLTVLGRNSRWSRAVSLVCSTSAEAWHPPEL 932
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEW------------TTPRESVKK--YILEWC- 458
P + V ++ + ++W RE++ Y +
Sbjct 933 AEPPQVELGTGMGVTVMRGMFGKDDGQIQWYGIIATINMTLAQPSREAINYTWYDHYYRG 992
Query 459 ------------VLSDKAPCITDWQQEDGT----VHRTYLRGNLAESKCYLITVTPVYAD 502
+ W GT + G L Y +V
Sbjct 993 CESFLALLFPNPFYPEPWAGPRSWTVPVGTEDCDNTQEICNGRLKSGFQYRFSVVAFSRL 1052
Query 503 GPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
PE+I A+ + P ++ +
Sbjct 1053 NT--PETILAFSAFSEPRASISLAIIPLT 1079
>sp|Q01344|IL5RA_HUMAN Interleukin-5 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL5RA PE=1 SV=2
Length=420
Score = 74.9 bits (182), Expect = 1e-12, Method: Composition-based stats.
Identities = 39/229 (17%), Positives = 73/229 (32%), Gaps = 34/229 (15%)
Query 125 PPEKPK----NLSCIVNEGK-----------KMRCEWDGGRETHLETNFTLKSEWA--TH 167
PP P NL+C N + + C W G + +T + L + T
Sbjct 121 PPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTE 180
Query 168 KFADCKAKRDTPT-SCTVDYSTVYFVN---IEVWVEAENALGKVTSDHINFDPVYKVKPN 223
+ + +C + + + V V + + F + N
Sbjct 181 ECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQIN 240
Query 224 PPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
PP N++ E + L + W P S + Y ++ + E +
Sbjct 241 PPLNVTA---EIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNG---YLQIEKLMTNAF 294
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGK---GYWSDWSEEASGITYEDRPSK 328
+ DL ++Y ++R G WS+WS+ E +P +
Sbjct 295 ISIIDDL---SKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLR 340
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 50/352 (14%), Positives = 94/352 (27%), Gaps = 59/352 (17%)
Query 204 LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN-PSIKSVII-LKYNIQY 261
LG + P K+ PP N ++ + + L W P + + L+Y ++
Sbjct 12 LGATEILQADLLPDEKISLLPPVNFTIKVTGLA--QVLLQWKPNPDQEQRNVNLEYQVKI 69
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+ E V L R + S S E
Sbjct 70 NAPKEDDYETRITESKC-------VTILHKGFSASVRTILQNDHSLLASSWASAELH--- 119
Query 322 YEDRPSKAPSFWYKIDPSHTQGYR-----------TVQLVWKTLPPFEANGKILDYEVTL 370
P +P T ++ W L +A Y +
Sbjct 120 ---APPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTW--LVGTDAPED-TQYFLYY 173
Query 371 TR--WKSHLQNYTVNA--------TKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD 420
W Q Y+ + T L+ R + V G S + +
Sbjct 174 RYGSWTEECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVN---GSSKHSAIRPFDQL 230
Query 421 FQ-----ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
F +P +++ A + L ++W P + + ++ V ++
Sbjct 231 FALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLM 290
Query 476 TVHRTYLRGNLAESKCYLITVTP-----VYADGPGS--PESIKAYLKQAPPS 520
T + +L++ Y + V G S + I + P
Sbjct 291 TNAFISIIDDLSK---YDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPL 339
>sp|P21183|IL5RA_MOUSE Interleukin-5 receptor subunit alpha OS=Mus
musculus OX=10090 GN=Il5ra PE=1 SV=1
Length=415
Score = 74.5 bits (181), Expect = 1e-12, Method: Composition-based stats.
Identities = 44/221 (20%), Positives = 79/221 (36%), Gaps = 36/221 (16%)
Query 125 PPEKP----KNLSCIVNE-----------GKKMRCEWDGGRETHLETNFTLKSEWA--TH 167
PP P NL+C + +RC W G++ +T + L + T
Sbjct 118 PPGSPGTSVTNLTCTTHTVVSSHTHLRPYQVSLRCTWLVGKDAPEDTQYFLYYRFGVLTE 177
Query 168 KFADCKAKR-DTPTSCTVDYSTV---YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN 223
K + + T+C + + F + V + + + F P+ + N
Sbjct 178 KCQEYSRDALNRNTACWFPRTFINSKGFEQLAVHINGSSKRAAIKPFDQLFSPLAIDQVN 237
Query 224 PPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQ-YRTKDASTWSQIPPEDTASTR 281
PP N++V E S+ L + W P S Y ++ Y TK+ I E + +
Sbjct 238 PPRNVTV---EIESNSLYIQWEKPLSAFPDHCFNYELKIYNTKNG----HIQKEKLIANK 290
Query 282 SSFTVQDLKPFTEYVFRIRCMKED---GKGYWSDWSEEASG 319
+ D+ + Y ++R G W +WS+
Sbjct 291 FISKIDDV---STYSIQVRAAVSSPCRMPGRWGEWSQPIYV 328
Score = 55.6 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 57/372 (15%), Positives = 109/372 (29%), Gaps = 68/372 (18%)
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLV 406
V L W P E L+Y V + + + +K L +VR ++
Sbjct 43 VLLHWDPNPDQEQRHVDLEYHVKINAPQEDEYDTRKTESKCVTPLHEG---FAASVRTIL 99
Query 407 GKS---DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE---------------WTTPRE 448
S A+ P + V W ++
Sbjct 100 KSSHTTLASSWVSAELKAPPGSPGTSVTNLTCTTHTVVSSHTHLRPYQVSLRCTWLVGKD 159
Query 449 SVK--KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADG-PG 505
+ + +Y L + C Y R L + T + + G
Sbjct 160 APEDTQYFLYYRFGVLTEKCQE------------YSRDALNRNTACWFPRTFINSKGFEQ 207
Query 506 SPESIKAYLKQAP---------PSK-----GPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
I K+A P P T ++ N ++W++ +
Sbjct 208 LAVHINGSSKRAAIKPFDQLFSPLAIDQVNPPRNVTVEIESNSLYIQWEKPLSAFPDHCF 267
Query 552 RNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA-AYTDEGGKDGPEFTFT 609
NY + Y T G+ + ++ +S + + Y +++ A + G ++
Sbjct 268 -NYELKIYNTKNGHIQKEKLIANKF---ISKIDDVSTYSIQVRAAVSSPCRMPGRWGEWS 323
Query 610 TPKF------AQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHI 663
P + + E IV+P F+L + + + ++P VP P KS+I
Sbjct 324 QPIYVGKERKSLVEWHLIVLPTAACFVLLIFSLICRVCH----LWTRLFPPVPAP-KSNI 378
Query 664 AQWSPHTPPRHN 675
+ P
Sbjct 379 -KDLPVVTEYEK 389
Score = 46.0 bits (107), Expect = 0.001, Method: Composition-based stats.
Identities = 41/338 (12%), Positives = 92/338 (27%), Gaps = 46/338 (14%)
Query 204 LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN-PSIKS-VIILKYNIQY 261
+G + + + K PP N ++ + + L W P + + L+Y+++
Sbjct 9 VGALATLQADLLNHKKFLLLPPVNFTIKATGLA--QVLLHWDPNPDQEQRHVDLEYHVKI 66
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM-KEDGKGYWSDW-SEEASG 319
+ E V L + +R + K S W S E
Sbjct 67 NAPQEDEYDTRKTESKC-------VTPLHEG--FAASVRTILKSSHTTLASSWVSAEL-- 115
Query 320 ITYEDRPSKAPSFWYKIDPSHTQG-----------YRTVQLVW---KTLPPFEANGKILD 365
P +P T +++ W K P
Sbjct 116 ----KAPPGSPGTSVTNLTCTTHTVVSSHTHLRPYQVSLRCTWLVGKDAPEDTQYFLYYR 171
Query 366 YEVTLTRWKSHLQNYTVNATKLTVNLTN-DRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
+ V + + + ++ T T + ++ G S A + F
Sbjct 172 FGVLTEKCQEYSRDALNRNTACWFPRTFINSKGFEQLAVHINGSSKRAAIKPFDQLFSPL 231
Query 425 H-----PVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV-LSDKAPCITDWQQEDGTVH 478
P ++ + N L+++W P + + + + + + ++
Sbjct 232 AIDQVNPPRNVTVEIESNSLYIQWEKPLSAFPDHCFNYELKIYNTKNGHIQKEKLIANKF 291
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ + Y I V + P + +
Sbjct 292 ISKIDDV----STYSIQVRAAVSSPCRMPGRWGEWSQP 325
>sp|A8DYP0|OBSCN_DROME Obscurin OS=Drosophila melanogaster OX=7227
GN=Unc-89 PE=1 SV=1
Length=4218
Score = 76.4 bits (186), Expect = 1e-12, Method: Composition-based stats.
Identities = 41/214 (19%), Positives = 73/214 (34%), Gaps = 39/214 (18%)
Query 123 GLPP---EKPKNLSCIVNEGKKMRC----------EWDGGRETHLETNFTLKSEWATHKF 169
G PP EKP+ ++ N+ + C +W K++ +
Sbjct 3651 GYPPFFREKPQTIAITENQPSHIHCFAVGDPKPCVQW-------------FKNDMVLTES 3697
Query 170 ADCKAKRDTPTSCTVDYSTVYFVNIEVW-VEAENALGKVTSDHINFDPVYKVKPNPPHNL 228
K D + + ++ V+ V A N +G+ + P+ P
Sbjct 3698 KRIKISVDEDGRSILRFEPALHFDVGVYKVVARNKVGQTVARCRIVVATLPDAPDSP--- 3754
Query 229 SVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
S + + L W P +L Y++QY+ + W+ + D + +
Sbjct 3755 --EISANSGTEILLRWKQPRDDGHSTVLCYSLQYKLSNCDAWTTVA--DNIDHEF-YLLH 3809
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
DL+P T Y FR+ G WS+ S T
Sbjct 3810 DLQPNTNYQFRLASKNRIG---WSEMGIPVSAST 3840
Score = 55.2 bits (131), Expect = 3e-06, Method: Composition-based stats.
Identities = 30/120 (25%), Positives = 43/120 (36%), Gaps = 11/120 (9%)
Query 224 PPHNLSVINSEELSSILKLTWTN--PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
PP + I S L L+W P I Y I+ W + T
Sbjct 2834 PPLSEGPIISRMTDRGLLLSWNPSVPLTPRYPIT-YQIEMMDLPEGDWRTLR---TGVRS 2889
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
+ +++L+PF +Y FR+R + G SD S TY + P Y P T
Sbjct 2890 CACDIRNLEPFRDYRFRVRVENKFGV---SDPSP--YTQTYRQKLVPDPPKTYTYLPPGT 2944
Score = 54.5 bits (129), Expect = 5e-06, Method: Composition-based stats.
Identities = 36/246 (15%), Positives = 71/246 (29%), Gaps = 21/246 (9%)
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
Y + + A L P + E +L W Q P D + +
Sbjct 3725 YKVVARNKVGQTVARCRIVVATL----PDAPDSPEISANSGTEILLRWKQ-PRDDGHSTV 3779
Query 552 RNYTIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
Y++ Y+ + T V + H Y L L +T Y R+A+ G
Sbjct 3780 LCYSLQYKLSNCDAWTTVADNIDHEFYLLHDLQPNTNYQFRLASKNRIG-----WSEMGI 3834
Query 611 PKFAQ---GEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKK--HIWPNVPD-PSKSHIA 664
P A G+ I + + L + + + H P+ + S ++
Sbjct 3835 PVSASTVGGDAPKIHITKAMKHLQQLTENGHQVVPEEERVHTDYHCEREPPNWVTDSSVS 3894
Query 665 QWSPHTPPRHNFNSKDQMYSDGNFTDV----SVVEIEANDKKPFPEDLKSLDLFKKEKIN 720
+ TD ++E+ ++ + + + E+I
Sbjct 3895 DKYSFISEIARGEFSTIVKGIQKSTDTVVVAKILEVTDENEDNVVAEFDNFKTLRHERIP 3954
Query 721 TEGHSS 726
+
Sbjct 3955 ALFSAY 3960
Score = 52.6 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 26/137 (19%), Positives = 44/137 (32%), Gaps = 7/137 (5%)
Query 386 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT 445
+ L D + + RN VG++ A I ++ A + + W
Sbjct 3713 RFEPALHFDVGVYKVVARNKVGQT-VARCRIVVATLPDAPDSPEISA-NSGTEILLRWKQ 3770
Query 446 PRESVKKYILEWCVLSDKAPCITDWQQEDGTV-HRTYLRGNLAESKCYLITVTPVYADG- 503
PR+ +L + + + C W + H YL +L + Y + G
Sbjct 3771 PRDDGHSTVLCYSLQYKLSNCDA-WTTVADNIDHEFYLLHDLQPNTNYQFRLASKNRIGW 3829
Query 504 --PGSPESIKAYLKQAP 518
G P S AP
Sbjct 3830 SEMGIPVSASTVGGDAP 3846
Score = 51.0 bits (120), Expect = 7e-05, Method: Composition-based stats.
Identities = 19/117 (16%), Positives = 33/117 (28%), Gaps = 6/117 (5%)
Query 422 QATHPVMD---LKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
P + + + D L + W +Y + + + P DW+ V
Sbjct 2830 SGAPPPLSEGPIISRMTDRGLLLSWNPSVPLTPRYPITYQIEMMDLPE-GDWRTLRTGVR 2888
Query 479 R-TYLRGNLAESKCYLITVTPVYADGPGSPES-IKAYLKQAPPSKGPTVRTKKVGKN 533
NL + Y V G P + Y ++ P T G +
Sbjct 2889 SCACDIRNLEPFRDYRFRVRVENKFGVSDPSPYTQTYRQKLVPDPPKTYTYLPPGTD 2945
Score = 45.6 bits (106), Expect = 0.003, Method: Composition-based stats.
Identities = 20/177 (11%), Positives = 54/177 (31%), Gaps = 12/177 (7%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTI---PKEQYTIINRTASSV 89
P++ + + C + W N + + + ++ S +
Sbjct 3660 PQTIAITENQPSHIHCF-------AVGDPKPCVQWFKNDMVLTESKRIKISVDEDGRSIL 3712
Query 90 TFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGG 149
F ++ + ++ ++ Q V I+ P+ P + N G ++ W
Sbjct 3713 RFEPALHFDVGVY-KVVARNKVGQTVARCRIVVATLPDAPDSPEISANSGTEILLRWKQP 3771
Query 150 RETHLETNFTLKSEWATHKF-ADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
R+ T ++ A + + + N + + ++N +G
Sbjct 3772 RDDGHSTVLCYSLQYKLSNCDAWTTVADNIDHEFYLLHDLQPNTNYQFRLASKNRIG 3828
Score = 42.2 bits (97), Expect = 0.028, Method: Composition-based stats.
Identities = 14/90 (16%), Positives = 24/90 (27%), Gaps = 3/90 (3%)
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI-IGNETAVNVDSSHT 575
APP ++ +L W+ I Y I + G+ +
Sbjct 2832 APPPLSEGPIISRMTDRGLLLSWNPSVPLTPRYPIT-YQIEMMDLPEGDWRTLRTGVRSC 2890
Query 576 EYTLSSLTSDTLYMVRMAAYTDEG-GKDGP 604
+ +L Y R+ G P
Sbjct 2891 ACDIRNLEPFRDYRFRVRVENKFGVSDPSP 2920
Score = 38.7 bits (88), Expect = 0.36, Method: Composition-based stats.
Identities = 19/116 (16%), Positives = 28/116 (24%), Gaps = 6/116 (5%)
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA-T 385
S AP + R + L W P I Y++ +
Sbjct 2830 SGAPPPLSEGPIISRMTDRGLLLSWNPSVPLTPRYPIT-YQIEMMDLPEGDWRTLRTGVR 2888
Query 386 KLTVNLTN----DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN 437
++ N Y + V N G SD + T P P
Sbjct 2889 SCACDIRNLEPFRDYRFRVRVENKFGVSDPSPYTQTYRQKLVPDPPKTYTYLPPGT 2944
>sp|P14753|EPOR_MOUSE Erythropoietin receptor OS=Mus musculus
OX=10090 GN=Epor PE=1 SV=1
Length=507
Score = 74.9 bits (182), Expect = 1e-12, Method: Composition-based stats.
Identities = 39/206 (19%), Positives = 71/206 (34%), Gaps = 18/206 (9%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD-------TPTSC 182
+ L C + + C W+ + ++ N++ + C +
Sbjct 48 EELLCFTQRLEDLVCFWEEAASSGMDFNYSFSYQLEGESRKSCSLHQAPTVRGSVRFWCS 107
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
T FV +E+ V + H V + P L +EE S ++ L
Sbjct 108 LPTADTSSFVPLELQVTEASG---SPRYHRIIHINEVVLLDAPAGLLARRAEEGSHVV-L 163
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA--STRSSFTVQDLKPFTEYVFRIR 300
W P + +I+Y ++ + R+ + +L+ T Y F +R
Sbjct 164 RWLPP---PGAPMTTHIRYEVDVSAGNRAGGTQRVEVLEGRTECVLSNLRGGTRYTFAVR 220
Query 301 CM--KEDGKGYWSDWSEEASGITYED 324
+ G+WS WSE AS +T D
Sbjct 221 ARMAEPSFSGFWSAWSEPASLLTASD 246
Score = 44.8 bits (104), Expect = 0.004, Method: Composition-based stats.
Identities = 34/145 (23%), Positives = 52/145 (36%), Gaps = 7/145 (5%)
Query 521 KGPTVRTKKVGKNE-AVLEWDQLPVDVQNGFIRNYTI--FYRTIIGNETAVNVDSSHTEY 577
+ ++ + VL W P IR Y + G V V TE
Sbjct 146 APAGLLARRAEEGSHVVLRWLPPPGAPMTTHIR-YEVDVSAGNRAGGTQRVEVLEGRTEC 204
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK---FAQGEIEAIVVPVCLAFLLTTL 634
LS+L T Y + A E G ++ P A I+ + L++ L
Sbjct 205 VLSNLRGGTRYTFAVRARMAEPSFSGFWSAWSEPASLLTASDLDPLILTLSLILVLISLL 264
Query 635 LGVLFCFNKRDLIKKHIWPNVPDPS 659
L VL + R +++ IWP +P P
Sbjct 265 LTVLALLSHRRTLQQKIWPGIPSPE 289
Score = 35.2 bits (79), Expect = 3.5, Method: Composition-based stats.
Identities = 21/179 (12%), Positives = 49/179 (27%), Gaps = 20/179 (11%)
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLA 398
TQ + W+ EA +D+ + + + + + + R+
Sbjct 52 CFTQRLEDLVCFWE-----EAASSGMDFNYSFSYQLEGESRKSCSLHQAPTVRGSVRFWC 106
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF--------------PKDNMLWVEWT 444
+L + + A H ++ + + + + + W
Sbjct 107 SLPTADTSSFVPLELQVTEASGSPRYHRIIHINEVVLLDAPAGLLARRAEEGSHVVLRWL 166
Query 445 TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVYAD 502
P + + + V Q+ + RT + NL Y V A+
Sbjct 167 PPPGAPMTTHIRYEVDVSAGNRAGGTQRVEVLEGRTECVLSNLRGGTRYTFAVRARMAE 225
>sp|Q8WZ75|ROBO4_HUMAN Roundabout homolog 4 OS=Homo sapiens OX=9606
GN=ROBO4 PE=1 SV=1
Length=1007
Score = 75.7 bits (184), Expect = 2e-12, Method: Composition-based stats.
Identities = 52/303 (17%), Positives = 88/303 (29%), Gaps = 43/303 (14%)
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP------------------ 434
+D N G ++ + + Q ++L A
Sbjct 200 SDEGTYMCVATNSAGHRESRAARVSIQEPQDYTEPVELLAVRIQLENVTLLNPDPAEGPK 259
Query 435 KDNMLWVEWTT--PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
+W+ W P + Y + + W +E ++ G L + Y
Sbjct 260 PRPAVWLSWKVSGPAAPAQSYTALFRTQTAPGGQGAPWAEELLAGWQSAELGGLHWGQDY 319
Query 493 LITVTPVYADGPGSPESIKA-YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
V P G ++ L + PS P T K G + W P + NG I
Sbjct 320 EFKVRPSSGRARGPDSNVLLLRLPEKVPSAPPQEVTLKPGNGTVFVSWVPPPAENHNGII 379
Query 552 RNYTIF-YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGP------ 604
R Y ++ V T+ +++ + Y V++AA T G +
Sbjct 380 RGYQVWSLGNTSLPPANWTVVGEQTQLEIATHMPGS-YCVQVAAVTGAGAGEPSRPVCLL 438
Query 605 -----EFTFTTPK---------FAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKH 650
E P V+ C L LLG C ++R + H
Sbjct 439 LEQAMERATQEPSEHGPWTLEQLRATLKRPEVIATCGVALWLLLLGTAVCIHRRRRARVH 498
Query 651 IWP 653
+ P
Sbjct 499 LGP 501
Score = 66.4 bits (160), Expect = 1e-09, Method: Composition-based stats.
Identities = 36/203 (18%), Positives = 62/203 (31%), Gaps = 14/203 (7%)
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP-PEDTASTRSSFTVQDLKPFTEYV 296
+ L+W S + Y +RT+ A P E+ + S + L +Y
Sbjct 262 PAVWLSWKV-SGPAAPAQSYTALFRTQTAPGGQGAPWAEELLAGWQSAELGGLHWGQDYE 320
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
F++R +G S E PS P + + G TV + W P
Sbjct 321 FKVRPSSGRARGPD---SNVLLLRLPEKVPSAPPQ-----EVTLKPGNGTVFVSWVPPPA 372
Query 357 FEANGKILDYEV-TLTRWKSHLQNYTVNATKLTVNLTN---DRYLATLTVRNLVGKSDAA 412
NG I Y+V +L N+TV + + + Y + G + +
Sbjct 373 ENHNGIIRGYQVWSLGNTSLPPANWTVVGEQTQLEIATHMPGSYCVQVAAVTGAGAGEPS 432
Query 413 VLTIPACDFQATHPVMDLKAFPK 435
+ +
Sbjct 433 RPVCLLLEQAMERATQEPSEHGP 455
>sp|P19235|EPOR_HUMAN Erythropoietin receptor OS=Homo sapiens
OX=9606 GN=EPOR PE=1 SV=1
Length=508
Score = 74.5 bits (181), Expect = 2e-12, Method: Composition-based stats.
Identities = 38/207 (18%), Positives = 71/207 (34%), Gaps = 17/207 (8%)
Query 129 PKNLSCIVNEGKKMRCEWDGGRETHL-ETNFTLKSEWATHKFADCKAKRD-------TPT 180
P+ L C + + C W+ + N++ + + C+ +
Sbjct 47 PEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFW 106
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
T FV +E+ V A + H V + P L ++E S +
Sbjct 107 CSLPTADTSSFVPLELRVTAASG---APRYHRVIHINEVVLLDAPVGLVARLADE-SGHV 162
Query 241 KLTWTNPSIKS-VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
L W P ++Y + + + + + R+ + +L+ T Y F +
Sbjct 163 VLRWLPPPETPMTSHIRYEVDVSAGNGAG--SVQRVEILEGRTECVLSNLRGRTRYTFAV 220
Query 300 RCM--KEDGKGYWSDWSEEASGITYED 324
R + G+WS WSE S +T D
Sbjct 221 RARMAEPSFGGFWSAWSEPVSLLTPSD 247
Score = 49.1 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 44/205 (21%), Positives = 72/205 (35%), Gaps = 26/205 (13%)
Query 531 GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVD--SSHTEYTLSSLTSDTLY 588
VL W P IR Y + G + V+ TE LS+L T Y
Sbjct 158 ESGHVVLRWLPPPETPMTSHIR-YEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRY 216
Query 589 MVRMAAYTDEGGKDGPEFTFTTPK--FAQGEIE-AIVVPVCLAFLLTTLLGVLFCFNKRD 645
+ A E G ++ P +++ I+ + ++ LL VL + R
Sbjct 217 TFAVRARMAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRR 276
Query 646 LIKKHIWPNVPDPS--------------------KSHIAQWSPHTPPRHNFNSKDQMYSD 685
+K+ IWP +P P WSP TP + + ++ S+
Sbjct 277 ALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSE 336
Query 686 GNFTDVSVVEIEANDKKPFPEDLKS 710
+ + VE +D+ P E + S
Sbjct 337 RCWGTMQAVEPGTDDEGPLLEPVGS 361
>sp|Q07303|EPOR_RAT Erythropoietin receptor OS=Rattus norvegicus
OX=10116 GN=Epor PE=2 SV=1
Length=507
Score = 74.5 bits (181), Expect = 2e-12, Method: Composition-based stats.
Identities = 39/206 (19%), Positives = 71/206 (34%), Gaps = 18/206 (9%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD-------TPTSC 182
+ L C + + C W+ + + N++ + C+ +
Sbjct 48 EELLCFTQRLEDLVCFWEEAANSGMGFNYSFSYQLEGESRKSCRLHQAPTVRGSMRFWCS 107
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
T FV +E+ V + H V + P L +EE S ++ L
Sbjct 108 LPTADTSSFVPLELQVTEASG---SPRYHRIIHINEVVLLDAPAGLLARRAEEGSHVV-L 163
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA--STRSSFTVQDLKPFTEYVFRIR 300
W P + +I+Y ++ + R+ + +L+ T Y F +R
Sbjct 164 RWLPP---PGAPMTTHIRYEVDVSAGNRAGGTQRVEVLEGRTECVLSNLRGGTRYTFAVR 220
Query 301 CM--KEDGKGYWSDWSEEASGITYED 324
+ G+WS WSE AS +T D
Sbjct 221 ARMAEPSFSGFWSAWSEPASLLTASD 246
Score = 47.2 bits (110), Expect = 7e-04, Method: Composition-based stats.
Identities = 35/155 (23%), Positives = 55/155 (35%), Gaps = 7/155 (5%)
Query 521 KGPTVRTKKVGKNE-AVLEWDQLPVDVQNGFIRNYTI--FYRTIIGNETAVNVDSSHTEY 577
+ ++ + VL W P IR Y + G V V TE
Sbjct 146 APAGLLARRAEEGSHVVLRWLPPPGAPMTTHIR-YEVDVSAGNRAGGTQRVEVLEGRTEC 204
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK---FAQGEIEAIVVPVCLAFLLTTL 634
LS+L T Y + A E G ++ P A I+ + L++ L
Sbjct 205 VLSNLRGGTRYTFAVRARMAEPSFSGFWSAWSEPASLLTASDLDPLILTLSLILVLISLL 264
Query 635 LGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPH 669
L VL + R +++ IWP +P P ++ H
Sbjct 265 LTVLALLSHRRALRQKIWPGIPSPENEFEGLFTTH 299
Score = 35.6 bits (80), Expect = 2.4, Method: Composition-based stats.
Identities = 20/179 (11%), Positives = 47/179 (26%), Gaps = 20/179 (11%)
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLA 398
TQ + W+ EA + + + + + + + R+
Sbjct 52 CFTQRLEDLVCFWE-----EAANSGMGFNYSFSYQLEGESRKSCRLHQAPTVRGSMRFWC 106
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF--------------PKDNMLWVEWT 444
+L + + A H ++ + + + + + W
Sbjct 107 SLPTADTSSFVPLELQVTEASGSPRYHRIIHINEVVLLDAPAGLLARRAEEGSHVVLRWL 166
Query 445 TPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVYAD 502
P + + + V Q+ + RT + NL Y V A+
Sbjct 167 PPPGAPMTTHIRYEVDVSAGNRAGGTQRVEVLEGRTECVLSNLRGGTRYTFAVRARMAE 225
>sp|Q08351|TPOR_MOUSE Thrombopoietin receptor OS=Mus musculus
OX=10090 GN=Mpl PE=2 SV=2
Length=625
Score = 74.5 bits (181), Expect = 2e-12, Method: Composition-based stats.
Identities = 63/461 (14%), Positives = 112/461 (24%), Gaps = 79/461 (17%)
Query 132 LSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKR------DTPTSCTVD 185
L+C + + C WD E + L + K C T C
Sbjct 38 LNCFSQTFEDLTCFWD-EEEAAPSGTYQLLYAYRGEKPRACPLYSQSVPTFGTRYVCQFP 96
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ + + +N T P PP + L++ W
Sbjct 97 AQDEVRLFFPLHLWVKNVSLNQTLIQRVLFVDSVGLPAPPRVIKA-RGGSQPGELQIHWE 155
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS----------------------- 282
P+ + L++ ++Y D+S + ST +
Sbjct 156 APAPEISDFLRHELRYGPTDSSNATAPSVIQLLSTETCCPTLWMPNPVPVLDQPPCVHPT 215
Query 283 ----------------SFTVQDLKPFTEYVFRIRCMKE--DGKGYWSDWSEEASGITYED 324
S V L+ Y ++R + +G W WS + D
Sbjct 216 ASQPHGPAPFLTVKGGSCLVSGLQAGKSYWLQLRSQPDGVSLRGSWGPWSFPVTV----D 271
Query 325 RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR------WKSHLQ 378
P A T + V W+ + G W+ +
Sbjct 272 LPGDA---VTIGLQCFTLDLKMVTCQWQQQDRTSSQGFFRHSRTRCCPTDRDPTWEKCEE 328
Query 379 NYTVNATK------LTVNLTNDRYL-ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
++ ND + + V G + + + P L
Sbjct 329 EEPRPGSQPALVSRCHFKSRNDSVIHILVEVTTAQGAVHSYLGSPFWIHQAVLLPTPSLH 388
Query 432 -AFPKDNMLWVEWTTPRESVKK---YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
L +EW + Y L + DW+ + ++ L
Sbjct 389 WREVSSGRLELEWQHQSSWAAQETCYQLRY-----TGEGREDWKVLEPSLGARGGTLELR 443
Query 488 ESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTK 528
Y + + GP A+ A S G
Sbjct 444 PRARYSLQLRARLN-GPTYQGPWSAWSPPARVSTGSETAWI 483
Score = 61.8 bits (148), Expect = 2e-08, Method: Composition-based stats.
Identities = 46/216 (21%), Positives = 76/216 (35%), Gaps = 19/216 (9%)
Query 119 TIISGLPPEKPKN-LSCIVNEGKKMRCEWDGGRETHLETNF----TLKSEWATH-KFADC 172
+ LP + L C + K + C+W T + F T + C
Sbjct 267 PVTVDLPGDAVTIGLQCFTLDLKMVTCQWQQQDRTSSQGFFRHSRTRCCPTDRDPTWEKC 326
Query 173 KAKRDTPTSCTVDYSTVYFVN-----IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHN 227
+ + P S S +F + I + VE A G V S + +++ P
Sbjct 327 EEEEPRPGSQPALVSRCHFKSRNDSVIHILVEVTTAQGAVHSYLGSPFWIHQAVLLP--T 384
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
S+ E S L+L W + S + Y ++Y + W + P A +
Sbjct 385 PSLHWREVSSGRLELEWQHQSSWAAQETCYQLRYTGEGREDWKVLEPSLGARGGT----L 440
Query 288 DLKPFTEYVFRIRCM--KEDGKGYWSDWSEEASGIT 321
+L+P Y ++R +G WS WS A T
Sbjct 441 ELRPRARYSLQLRARLNGPTYQGPWSAWSPPARVST 476
>sp|P26225|GUNB_CELFI Endoglucanase B OS=Cellulomonas fimi OX=1708
GN=cenB PE=3 SV=1
Length=1045
Score = 74.5 bits (181), Expect = 3e-12, Method: Composition-based stats.
Identities = 49/313 (16%), Positives = 91/313 (29%), Gaps = 24/313 (8%)
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + + L+W + + Y + YR + + +T +++ ++DL
Sbjct 658 VATGVTTVGASLSWAASTDAGSGVAGYEL-YRVQGTTQ-----TLVGTTTAAAYILRDLT 711
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
P T Y + ++ G S S + T ++ P+ S L
Sbjct 712 PGTAYSYVVKAKDVA--GNVSAASAAVTFTTDTTGETEPPTTPGTPVASAVTSTGA-TLA 768
Query 351 WKTLPPFEANGKILDYEV--TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK 408
W A + Y+V + + TV L+ + Y + +N+ G
Sbjct 769 WAPSTGDPA---VSGYDVLRVQGTTTTVVAQTTVPTVTLSGLTPSTAYTYAVRAKNVAGD 825
Query 409 SDA-------AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
A P T P + + + WT +S + + VL
Sbjct 826 VSALSAPVTFTTAAPPVDTVAPTVPGTPVASNVATTGATLTWTASTDSGGSGLAGYEVL- 884
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
+ T T L G L + Y V G S S P +
Sbjct 885 -RVSGTTQTLVASPTTATVALAG-LTPATAYSYVVRAKDGAGNVSAVSSPVTFTTLPVTS 942
Query 522 GPTVRTKKVGKNE 534
P+ +
Sbjct 943 TPSCTVVYSTNSW 955
Score = 64.9 bits (156), Expect = 3e-09, Method: Composition-based stats.
Identities = 42/286 (15%), Positives = 69/286 (24%), Gaps = 28/286 (10%)
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN--LTNDRYLATLTVRNLV 406
L W +A + YE+ + + T A + Y + +++
Sbjct 669 LSWAAS--TDAGSGVAGYELYRVQGTTQTLVGTTTAAAYILRDLTPGTAYSYVVKAKDVA 726
Query 407 GKSDAAVLTIPACDFQATHPVMD------LKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
G AA + + + + W + + VL
Sbjct 727 GNVSAASAAVTFTTDTTGETEPPTTPGTPVASAVTSTGATLAWAPSTGDPA--VSGYDVL 784
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP--GSPESIKAYLKQAP 518
+ T T T L S Y V G + P
Sbjct 785 RVQGTTTTV---VAQTTVPTVTLSGLTPSTAYTYAVRAKNVAGDVSALSAPVTFTTAAPP 841
Query 519 -----PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSS 573
P+ T V A L W D + Y + + G + +
Sbjct 842 VDTVAPTVPGTPVASNVATTGATLTWTAS-TDSGGSGLAGYEVLR--VSGTTQTLVASPT 898
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEG---GKDGPEFTFTTPKFAQG 616
L+ LT T Y + A G P T P +
Sbjct 899 TATVALAGLTPATAYSYVVRAKDGAGNVSAVSSPVTFTTLPVTSTP 944
Score = 41.8 bits (96), Expect = 0.036, Method: Composition-based stats.
Identities = 32/169 (19%), Positives = 42/169 (25%), Gaps = 15/169 (9%)
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVR------TKKVGKN 533
Y+ +L Y V G S S + V
Sbjct 704 AYILRDLTPGTAYSYVVKAKDVAGNVSAASAAVTFTTDTTGETEPPTTPGTPVASAVTST 763
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA 593
A L W + + Y + + G T V ++ TLS LT T Y +
Sbjct 764 GATLAWA---PSTGDPAVSGYDVLR--VQGTTTTVVAQTTVPTVTLSGLTPSTAYTYAVR 818
Query 594 AYTDEG--GKDGPEFTFTT--PKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
A G TFTT P PV T
Sbjct 819 AKNVAGDVSALSAPVTFTTAAPPVDTVAPTVPGTPVASNVATTGATLTW 867
>sp|Q6PDN3|MYLK_MOUSE Myosin light chain kinase, smooth muscle
OS=Mus musculus OX=10090 GN=Mylk PE=1 SV=3
Length=1941
Score = 74.9 bits (182), Expect = 3e-12, Method: Composition-based stats.
Identities = 38/154 (25%), Positives = 59/154 (38%), Gaps = 9/154 (6%)
Query 197 WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT-NPSIKSVIIL 255
+ EN LG + + KP+PP + S+ SS L L+W + +
Sbjct 1331 TLVVENKLGSRQAQ---VNLTVVDKPDPPAG-TPCASDIRSSSLTLSWYGSSYDGGSAVQ 1386
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
YN++ + W ++ +SF VQDL P EY FR+R + G S SE
Sbjct 1387 SYNVEIWDTEDKVWKEL----ATCRSTSFNVQDLLPDREYKFRVRAVNVYGTSEPSQESE 1442
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
+ + P + YRTV +
Sbjct 1443 LTAVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTV 1476
Score = 44.1 bits (102), Expect = 0.008, Method: Composition-based stats.
Identities = 21/148 (14%), Positives = 38/148 (26%), Gaps = 5/148 (3%)
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+ + + T L CY + V ++ K PP+
Sbjct 1301 QESEHIKVENGESGSKLTILAARQEHCGCYTLVVENKLGSRQA-QVNLTVVDKPDPPAGT 1359
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
P + + L W +++Y + T + + L
Sbjct 1360 P--CASDIRSSSLTLSW-YGSSYDGGSAVQSYNVEIWDTEDKVWKELATCRSTSFNVQDL 1416
Query 583 TSDTLYMVRMAAYTDEG-GKDGPEFTFT 609
D Y R+ A G + E T
Sbjct 1417 LPDREYKFRVRAVNVYGTSEPSQESELT 1444
Score = 41.4 bits (95), Expect = 0.050, Method: Composition-based stats.
Identities = 16/124 (13%), Positives = 36/124 (29%), Gaps = 11/124 (9%)
Query 320 ITYEDRPSKAPSFWYKIDPSHT-QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
+T D+P P + ++ L W ++ + Y V + + +
Sbjct 1347 LTVVDKPDPP-----AGTPCASDIRSSSLTLSWYGSS-YDGGSAVQSYNVEIWDTEDKVW 1400
Query 379 NYTVNATKLTVN----LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP 434
+ N L + Y + N+ G S+ + + + D
Sbjct 1401 KELATCRSTSFNVQDLLPDREYKFRVRAVNVYGTSEPSQESELTAVGEKPEEPKDEVEVS 1460
Query 435 KDNM 438
D+
Sbjct 1461 DDDE 1464
Score = 39.1 bits (89), Expect = 0.24, Method: Composition-based stats.
Identities = 29/215 (13%), Positives = 59/215 (27%), Gaps = 16/215 (7%)
Query 32 SPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTF 91
PE V+ L K + W I + ++ + S
Sbjct 1265 FPEDQKVRAGEPVE----LFGKVAGTQPITCK---WMKFRKQIQESEHIKVENGESGSKL 1317
Query 92 TDIASLNIQLTC-NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVN-EGKKMRCEWDGG 149
T +A+ C ++ +L + + P+ P C + + W G
Sbjct 1318 TILAARQEHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1377
Query 150 RETHLE--TNFTLKSEWATHK-FADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK 206
++ ++ K + + R T + + V A N G
Sbjct 1378 SYDGGSAVQSYNVEIWDTEDKVWKELATCRSTSFNVQDLLPDR---EYKFRVRAVNVYGT 1434
Query 207 VTSDHINFDPVYKVKPNPPHN-LSVINSEELSSIL 240
+ KP P + + V + +E +
Sbjct 1435 SEPSQESELTAVGEKPEEPKDEVEVSDDDEKEPEV 1469
>sp|Q29000|IGF1R_PIG Insulin-like growth factor 1 receptor (Fragments)
OS=Sus scrofa OX=9823 GN=IGF1R PE=2 SV=2
Length=304
Score = 71.8 bits (174), Expect = 4e-12, Method: Composition-based stats.
Identities = 33/180 (18%), Positives = 64/180 (36%), Gaps = 17/180 (9%)
Query 478 HRTYLRGNLAESKCYLITVTPVYAD----GPGSPESIKAYL--KQAPPSKGPTVRTKKVG 531
RT + NL Y I + + G + + A + V +
Sbjct 1 ERTVI-SNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRP 59
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY---TLSSLTSDTLY 588
+N L+W + + NG I Y I Y + + ++ + +Y L+ L Y
Sbjct 60 ENSIFLKWPE--PENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPG-NY 116
Query 589 MVRMAAYTDEGGKDGPEFTFTTPKFAQGE----IEAIVVPVCLAFLLTTLLGVLFCFNKR 644
R+ A + G E F + I +PV + ++ L+ +L+ F+++
Sbjct 117 TARIQATSLSGNGSWTEPVFFYVQAKTTYENFIHLIIALPVAVLLIVGGLVIMLYVFHRK 176
Score = 51.8 bits (122), Expect = 1e-05, Method: Composition-based stats.
Identities = 24/131 (18%), Positives = 44/131 (34%), Gaps = 15/131 (11%)
Query 191 FVNIEVWVEAEN----ALGKVTSDHINFDPV----YKVKPNPPHNLSVINSEELSSILKL 242
F + + + N LG S+ + + P P V + + L
Sbjct 11 FTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGP-----VTWEPRPENSIFL 65
Query 243 TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
W P + +IL Y I+Y ++ + ++ + L P Y RI+
Sbjct 66 KWPEPENPNGLILMYEIKYGSQVEDQRECVSRQE-YRKYGGAKLNRLNPG-NYTARIQAT 123
Query 303 KEDGKGYWSDW 313
G G W++
Sbjct 124 SLSGNGSWTEP 134
Score = 48.7 bits (114), Expect = 1e-04, Method: Composition-based stats.
Identities = 26/147 (18%), Positives = 42/147 (29%), Gaps = 13/147 (9%)
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGY 344
+ +L+PFT Y I + + S T P++ +
Sbjct 4 VISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTM---PAEGADDIPGPVTWEPRPE 60
Query 345 RTVQLVWKTLPPFEANGKILDYEVTL-------TRWKSHLQNYTVNATKLTVNLTNDRYL 397
++ L W P NG IL YE+ S + KL + Y
Sbjct 61 NSIFLKW--PEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN-YT 117
Query 398 ATLTVRNLVGKSDAAVLTIPACDFQAT 424
A + +L G + T
Sbjct 118 ARIQATSLSGNGSWTEPVFFYVQAKTT 144
>sp|Q9R044|NPHN_RAT Nephrin OS=Rattus norvegicus OX=10116 GN=Nphs1
PE=1 SV=2
Length=1252
Score = 74.1 bits (180), Expect = 4e-12, Method: Composition-based stats.
Identities = 41/210 (20%), Positives = 68/210 (32%), Gaps = 21/210 (10%)
Query 132 LSCIVNEGKKMRCEW--DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
L C + W +G + +T + + +
Sbjct 875 LHCRARGVPNIDFTWTKNGVPLDLQDPRYTEHRYHQGVVHSSLLTIANVSAAQDYAL--- 931
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
A NALG SDH N V +P+PP L V++ + L W P
Sbjct 932 ------FKCTATNALG---SDHTNIQLVSISRPDPPLGLKVVSI--SPHSVGLEWK-PGF 979
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ ++ I+Y + + + T ++FT+ LKP T Y + G
Sbjct 980 DGGLPQRFQIRYEALETPGFLHVDVLPT--QATTFTLTGLKPSTRYRIWLLASNALGDSG 1037
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
+D + S T P +AP P+
Sbjct 1038 LTDKGIQVSVTTP--GPDQAPEDTDHQLPT 1065
Score = 54.9 bits (130), Expect = 4e-06, Method: Composition-based stats.
Identities = 31/205 (15%), Positives = 60/205 (29%), Gaps = 8/205 (4%)
Query 31 ISPESPVVQLH------SNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINR 84
+ +P+ ++ S+ T C + F N + + +Y
Sbjct 854 VDQPTPLTKVAAAGDSTSSATLHCRARGVPNIDFTWTKNGVPLDLQDPRYTEHRYHQGVV 913
Query 85 TASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRC 144
+S +T ++++ L + I ++S P+ P L + +
Sbjct 914 HSSLLTIANVSAAQDYALFKCTATNALGSDHTNIQLVSISRPDPPLGLKVVSISPHSVGL 973
Query 145 EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
EW G + L F ++ E T + +W+ A NAL
Sbjct 974 EWKPGFDGGLPQRFQIRYEALETPGFLHVDVLPTQATTFTLTGLKPSTRYRIWLLASNAL 1033
Query 205 GKV--TSDHINFDPVYKVKPNPPHN 227
G T I P +
Sbjct 1034 GDSGLTDKGIQVSVTTPGPDQAPED 1058
Score = 52.2 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 33/157 (21%), Positives = 58/157 (37%), Gaps = 13/157 (8%)
Query 463 KAPCITDWQQEDGTVHRTYL-RGNLAESKCY-LITVTPVYADGPGSPESIKAYLKQAPPS 520
+ P T+ + G VH + L N++ ++ Y L T A G + + P
Sbjct 899 QDPRYTEHRYHQGVVHSSLLTIANVSAAQDYALFKCTATNALGSDHTNIQLVSI--SRPD 956
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET-AVNV-DSSHTEYT 578
++ + + LEW G + + I Y + V+V + T +T
Sbjct 957 PPLGLKVVSISPHSVGLEW---KPGFDGGLPQRFQIRYEALETPGFLHVDVLPTQATTFT 1013
Query 579 LSSLTSDTLYMVRMAAYTDEGGKD----GPEFTFTTP 611
L+ L T Y + + A G G + + TTP
Sbjct 1014 LTGLKPSTRYRIWLLASNALGDSGLTDKGIQVSVTTP 1050
Score = 38.7 bits (88), Expect = 0.34, Method: Composition-based stats.
Identities = 17/109 (16%), Positives = 31/109 (28%), Gaps = 7/109 (6%)
Query 397 LATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT--PRESVKKYI 454
L T N +G + + + + P + +EW +++
Sbjct 931 LFKCTATNALGSDHTNIQLVSISRPDPPLGLKVVSISPHS--VGLEWKPGFDGGLPQRFQ 988
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADG 503
+ + L D T T+ L S Y I + A G
Sbjct 989 IRYEALETPGFLHVDVL---PTQATTFTLTGLKPSTRYRIWLLASNALG 1034
>sp|Q8TER0|SNED1_HUMAN Sushi, nidogen and EGF-like domain-containing
protein 1 OS=Homo sapiens OX=9606 GN=SNED1 PE=1 SV=2
Length=1413
Score = 74.1 bits (180), Expect = 5e-12, Method: Composition-based stats.
Identities = 42/281 (15%), Positives = 76/281 (27%), Gaps = 22/281 (8%)
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY-----TVNA 384
P K++ G V + W A + Y VT + T ++
Sbjct 908 PPTALKMERVEESG---VSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSS 964
Query 385 TKLTVNLTNDRYLATL--TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE 442
+L Y ++ RN K+D + + + + + V+
Sbjct 965 HQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTASTISVQ 1024
Query 443 W--TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY 500
W R + + V + D + + L K Y I +T +
Sbjct 1025 WALHRIRHATVSGV---RVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTLS 1081
Query 501 A-DGPGSPESIKAYLK---QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
G P A P + +V A + WD + Y I
Sbjct 1082 GLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAP---TPGSLLEAYVI 1138
Query 557 FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
T ++ + YT+ L Y + + A
Sbjct 1139 NVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQS 1179
Score = 52.2 bits (123), Expect = 3e-05, Method: Composition-based stats.
Identities = 53/382 (14%), Positives = 108/382 (28%), Gaps = 34/382 (9%)
Query 77 EQYTIINRTASSVTFTDI---ASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLS 133
+ ++RT SS + + NI + +++ P +
Sbjct 953 RRTDFVDRTRSSHQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFE 1012
Query 134 CIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN 193
+ +W R H + S D D + +
Sbjct 1013 VTNVTASTISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKR 1072
Query 194 IEVWVEAENALG--KVTSDHINFDPVYK-VKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+ + + L + ++ + P + +P PP NL+ ++ + W P+
Sbjct 1073 YTIQLTTLSGLRGEEHPTESLATAPTHVWTRPLPPANLTAARV--TATSAHVVWDAPT-P 1129
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
++ Y I T ++ +P +S+TV+DL P Y + ++ G
Sbjct 1130 GSLLEAYVINVTTSQSTKSRYVP----NGKLASYTVRDLLPGRRYQLSVIAVQSTELGP- 1184
Query 311 SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
SE A A W H G+ L + P L
Sbjct 1185 -QHSEPAHLYIITSPRDGADRRW------HQGGHHPRVLKNRPPPARLPE---------L 1228
Query 371 TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
H T L + R ++ R G S + T+ + +
Sbjct 1229 RLLNDHSAPETPTQPPRFSELVDGRG--RVSAR--FGGSPSKAATVRSQPTASAQLENME 1284
Query 431 KAFPKDNMLWVEWTTPRESVKK 452
+A + ++ + +
Sbjct 1285 EAPKRVSLALQLPEHGSKDIGN 1306
>sp|O35228|IL27B_MOUSE Interleukin-27 subunit beta OS=Mus musculus
OX=10090 GN=Ebi3 PE=1 SV=1
Length=228
Score = 69.9 bits (169), Expect = 6e-12, Method: Composition-based stats.
Identities = 40/200 (20%), Positives = 79/200 (40%), Gaps = 17/200 (9%)
Query 136 VNEGKKMRCEWDG--GRETHLETNFTLKSEWA---THKFADCKAKRDTPTSCTVDYSTVY 190
+ C W + T+F + C + + CT+ ++
Sbjct 37 SRYPVAVDCSWTPLQAPNSTRSTSFIATYRLGVATQQQSQPCLQRSPQASRCTIPDVHLF 96
Query 191 -FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS- 248
V + V A + G +S + F +KP+PP + + + + L++ W P+
Sbjct 97 STVPYMLNVTAVHP-GGASSSLLAFVAERIIKPDPPEGVRLRTAGQR---LQVLWHPPAS 152
Query 249 --IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ LKY ++YR + AS + Q+ P + ++FT+++ KP +Y ++
Sbjct 153 WPFPDIFSLKYRLRYRRRGASHFRQVGPIEA----TTFTLRNSKPHAKYCIQVSAQDLTD 208
Query 307 KGYWSDWSEEASGITYEDRP 326
G SDWS + +P
Sbjct 209 YGKPSDWSLPGQVESAPHKP 228
Score = 34.8 bits (78), Expect = 2.5, Method: Composition-based stats.
Identities = 23/130 (18%), Positives = 40/130 (31%), Gaps = 3/130 (2%)
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI 454
Y+ +T + G S +++L A P ++ L V W P I
Sbjct 100 PYMLNVTAVHPGGAS-SSLLAFVAERIIKPDPPEGVRLRTAGQRLQVLWHPPASWPFPDI 158
Query 455 L-EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
L + + ++Q T+ N Y I V+ G P
Sbjct 159 FSLKYRLRYRRRGASHFRQVGPIEATTFTLRNSKPHAKYCIQVSAQDLTDYGKPSDWSLP 218
Query 514 LK-QAPPSKG 522
+ ++ P K
Sbjct 219 GQVESAPHKP 228
Score = 34.1 bits (76), Expect = 5.1, Method: Composition-based stats.
Identities = 34/200 (17%), Positives = 62/200 (31%), Gaps = 20/200 (10%)
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES--------VKKYILEW 457
+S T + P + A + WT + + Y L
Sbjct 13 ASRSPGYTET---ALVALSQPRVQCHASRYPVAVDCSWTPLQAPNSTRSTSFIATYRLGV 69
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
PC+ Q+ T +L + Y++ VT V G+ S+ A++ +
Sbjct 70 ATQQQSQPCL---QRSPQASRCTIPDVHLFSTVPYMLNVTAV--HPGGASSSLLAFVAER 124
Query 518 --PPSKGPTVRTKKVGKNEAVLEWDQLPV-DVQNGFIRNYTIFYRTIIGNETAVNVDSSH 574
P VR + G + W + F Y + YR +
Sbjct 125 IIKPDPPEGVRLRTAG-QRLQVLWHPPASWPFPDIFSLKYRLRYRRRGASHFRQVGPIEA 183
Query 575 TEYTLSSLTSDTLYMVRMAA 594
T +TL + Y ++++A
Sbjct 184 TTFTLRNSKPHAKYCIQVSA 203
>sp|Q8BZ52|FSD2_MOUSE Fibronectin type III and SPRY domain-containing
protein 2 OS=Mus musculus OX=10090 GN=Fsd2 PE=1 SV=3
Length=716
Score = 73.0 bits (177), Expect = 7e-12, Method: Composition-based stats.
Identities = 38/199 (19%), Positives = 65/199 (33%), Gaps = 24/199 (12%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
P+ P + S +++ W+ S +V Y + YR S+ + E T
Sbjct 336 IPAPSAPVINPQAPNSATGSSVRVCWSLYSDDTVE--SYQLSYRPVQDSSSGKDRAEFTM 393
Query 279 STRSSF-TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
+ ++ +V +L+P T+Y F + G S SE A +T PS
Sbjct 394 MVKETYCSVTNLEPNTQYEFWVIAQNRTG---PSPCSEHAVYMTAPSPPSIKTEAIR--- 447
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL----TRWKSHLQNYTVNATKLTVNL-- 391
V + W++ + Y V L T S + V +
Sbjct 448 ----SCEEAVLICWESGNLN----PVDSYTVELIQAETPEASGVTESVVGIPTCESLIQL 499
Query 392 -TNDRYLATLTVRNLVGKS 409
Y + N+ G S
Sbjct 500 QPRHSYTIYVRALNVGGTS 518
Score = 66.0 bits (159), Expect = 1e-09, Method: Composition-based stats.
Identities = 30/197 (15%), Positives = 62/197 (31%), Gaps = 15/197 (8%)
Query 411 AAVLTIPACDFQATHPVMDLKA--FPKDNMLWVEWTTPRESVKK-YILEWCVLSDKAPCI 467
++ + PV++ +A + + V W+ + + Y L + + D +
Sbjct 327 EQLMDAINTIPAPSAPVINPQAPNSATGSSVRVCWSLYSDDTVESYQLSYRPVQDSSSGK 386
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
+ NL + Y V GP Y+ PS P+++T
Sbjct 387 DRAEFTMMVKETYCSVTNLEPNTQYEFWVIAQNRTGPSPCSEHAVYM--TAPS-PPSIKT 443
Query 528 KKVGK--NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSHTEYTLSSL 582
+ + ++ W+ + +YT+ E +V T +L L
Sbjct 444 EAIRSCEEAVLICWE----SGNLNPVDSYTVELIQAETPEASGVTESVVGIPTCESLIQL 499
Query 583 TSDTLYMVRMAAYTDEG 599
Y + + A G
Sbjct 500 QPRHSYTIYVRALNVGG 516
Score = 61.4 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 25/132 (19%), Positives = 45/132 (34%), Gaps = 10/132 (8%)
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
E WV A+N G + VY P+PP ++ + + W + ++
Sbjct 408 NTQYEFWVIAQNRTG---PSPCSEHAVYMTAPSPP-SIKTEAIRSCEEAVLICWESGNLN 463
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
+ Y ++ + S + +Q L+P Y +R + G
Sbjct 464 --PVDSYTVELIQAETPEASGVTESVVGIPTCESLIQ-LQPRHSYTIYVRALNVGGT--- 517
Query 311 SDWSEEASGITY 322
S SE A+ T
Sbjct 518 SARSEPATVHTT 529
Score = 51.8 bits (122), Expect = 2e-05, Method: Composition-based stats.
Identities = 16/120 (13%), Positives = 36/120 (30%), Gaps = 10/120 (8%)
Query 513 YLKQAPPSKGPTVRTKK-VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET----- 566
AP + + + + W D + +Y + YR + + +
Sbjct 334 NTIPAPSAPVINPQAPNSATGSSVRVCWSLYSDDT----VESYQLSYRPVQDSSSGKDRA 389
Query 567 AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVC 626
+ T ++++L +T Y + A G E + I+ + C
Sbjct 390 EFTMMVKETYCSVTNLEPNTQYEFWVIAQNRTGPSPCSEHAVYMTAPSPPSIKTEAIRSC 449
Score = 47.5 bits (111), Expect = 5e-04, Method: Composition-based stats.
Identities = 26/194 (13%), Positives = 56/194 (29%), Gaps = 20/194 (10%)
Query 328 KAPSFWYKIDPSHTQG--YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ------- 378
APS I+P +V++ W + Y+++ +
Sbjct 337 PAPSA-PVINPQAPNSATGSSVRVCWSLYSDDT----VESYQLSYRPVQDSSSGKDRAEF 391
Query 379 NYTVNATKLTVNLT--NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
V T +V N +Y + +N G S + + + + +
Sbjct 392 TMMVKETYCSVTNLEPNTQYEFWVIAQNRTGPSPCSEHAVY-MTAPSPPSIKTEAIRSCE 450
Query 437 NMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLIT 495
+ + W + V Y +E ++ + P + + + L Y I
Sbjct 451 EAVLICWESGNLNPVDSYTVE--LIQAETPEASGVTESVVGIPTCESLIQLQPRHSYTIY 508
Query 496 VTPVYADGPGSPES 509
V + G +
Sbjct 509 VRALNVGGTSARSE 522
>sp|P70402|MYBPH_MOUSE Myosin-binding protein H OS=Mus musculus
OX=10090 GN=Mybph PE=2 SV=2
Length=483
Score = 72.2 bits (175), Expect = 8e-12, Method: Composition-based stats.
Identities = 55/324 (17%), Positives = 103/324 (32%), Gaps = 26/324 (8%)
Query 221 KPNPPH------NLSVINSEELSSILKLTWTNPSIKSVIILK-YNIQYRTKDASTWSQIP 273
KP PP L + + S L ++W P + L+ Y +++ + AS W +
Sbjct 68 KPEPPSEDVPSAPLRLTLEDVSHSSLTVSWEPPEKLGKLGLQGYVLEFCREGASEWVPVN 127
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSF 332
P T+ TV++L ++ R+ + G G + + + P + P
Sbjct 128 PRPVMVTQQ--TVRNLALGDKFFLRVTAVSSAGAGPPAVLDQPVHIQEITEAPKIRVPRH 185
Query 333 WYKIDPSHTQGYRTVQLVWKTLPPFE----ANGKILDYE-VTLTRWKSHLQNYTVNATKL 387
+ +Q+ ++ P + NG LD + V + + +A +
Sbjct 186 LRQTYIRQVGESVNLQIPFQGKPKPQVSWTHNGHALDNQRVNVRSGDQDSILFIRSAQRA 245
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPR 447
D LTV L G A + I + + L N +EWT P+
Sbjct 246 ------DSGRYELTVH-LEGLEAKASIDILVIEKPGPPSSIKLLDVWGCNAA-LEWTPPQ 297
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
++ +L + V + + T +L Y V G
Sbjct 298 DTGNTELLGYTVQKADKRTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCG---L 354
Query 508 ESIKAYLKQAPPSKGPTVRTKKVG 531
+ K+ + K
Sbjct 355 SDLATTTKELAHIHKADITAKPRE 378
Score = 63.0 bits (151), Expect = 7e-09, Method: Composition-based stats.
Identities = 53/322 (16%), Positives = 96/322 (30%), Gaps = 29/322 (9%)
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ-- 378
T + PS+ + ++ + W+ G + Y + R +
Sbjct 67 TKPEPPSEDVPSAPLRLTLEDVSHSSLTVSWEPPEKLGKLG-LQGYVLEFCREGASEWVP 125
Query 379 ----NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV------- 427
V + D++ +T + G AVL P + T
Sbjct 126 VNPRPVMVTQQTVRNLALGDKFFLRVTAVSSAGAGPPAVLDQPVHIQEITEAPKIRVPRH 185
Query 428 ---MDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
++ + L + + + + L ++ + Q+ R+ R
Sbjct 186 LRQTYIRQVGESVNLQIPFQGKPKPQVSWTHNGHALDNQRVNVRSGDQDSILFIRSAQRA 245
Query 485 NLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
+ S Y +TV +G + SI + + P +++ V A LEW P
Sbjct 246 D---SGRYELTVH---LEGLEAKASIDILVIEK-PGPPSSIKLLDVWGCNAALEWTP-PQ 297
Query 545 DVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
D N + YT+ G V T T+S L Y R+ + G D
Sbjct 298 DTGNTELLGYTVQKADKRTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSD- 356
Query 604 PEFTFTTPKFAQGEIEAIVVPV 625
TT + A I
Sbjct 357 --LATTTKELAHIHKADITAKP 376
Score = 52.2 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 6/95 (6%)
Query 213 NFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTKDASTWSQ 271
+ D + KP PP ++ +++ ++ L WT P + +L Y +Q K W
Sbjct 264 SIDILVIEKPGPPSSIKLLDVWGCNAA--LEWTPPQDTGNTELLGYTVQKADKRTGQWFT 321
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ ++ T+ DL Y FR+ G
Sbjct 322 VLERY---HPTTCTISDLIIGNSYSFRVFSENLCG 353
Score = 38.7 bits (88), Expect = 0.23, Method: Composition-based stats.
Identities = 29/177 (16%), Positives = 59/177 (33%), Gaps = 16/177 (9%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTD 93
++ + Q+ + + K + W N + ++ + + S+ F
Sbjct 188 QTYIRQVGESVNLQIPFQGK-------PKPQVSWTHNGHALDNQRVNVRSGDQDSILF-- 238
Query 94 IASLNIQLTCNILTFGQLE--QNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRE 151
I S + LE + I I+ P P ++ + G EW ++
Sbjct 239 IRSAQRADSGRYELTVHLEGLEAKASIDILVIEKPGPPSSIKLLDVWGCNAALEWTPPQD 298
Query 152 THLETN---FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
T T +T++ +R PT+CT+ + + V +EN G
Sbjct 299 TG-NTELLGYTVQKADKRTGQWFTVLERYHPTTCTIS-DLIIGNSYSFRVFSENLCG 353
>sp|Q25410|MIPR_LYMST Putative molluscan insulin-related peptide(s)
receptor OS=Lymnaea stagnalis OX=6523 PE=2 SV=1
Length=1607
Score = 73.4 bits (178), Expect = 9e-12, Method: Composition-based stats.
Identities = 69/502 (14%), Positives = 132/502 (26%), Gaps = 94/502 (19%)
Query 227 NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT----------------KDASTWS 270
N++V ++I L W +L Y + Y+ W
Sbjct 520 NVTVEKIAHNAAI--LAWNKYKADERQLLTYILNYKEIKDESNDINIFQGRDLCSHDLWM 577
Query 271 QIPPEDTASTRSSF--TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
+ + DLKPFT Y I+ + + + TY PS+
Sbjct 578 TREYAPKEGPEADQIGMLYDLKPFTTYAVYIQAYT-VSTATHAAMTNILTFTTYPFHPSE 636
Query 329 APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY-------- 380
++ +++ WK PP NG I Y++ + + + ++Y
Sbjct 637 PTDLVAI-----SEDPHELRVSWK--PPKYPNGNITHYKIVYHKLELNEKSYEQRNYCRD 689
Query 381 --TVNATKLTVNLTNDRYLATLTVRNL---VGKSDAAVLTIPAC---------------- 419
K V + + + + KS + T
Sbjct 690 PLVHQKKKEKVKIEEEGKKINNSANSNCCKCPKSKEEMDTESRKREIEMYFEDYLHKHIY 749
Query 420 ----DFQATHPVMDLKAFPKDNMLWVEWTTPR-----ESVKKYILEWCVLSDKAPCITDW 470
D ++ ++ + + + E Y++E I
Sbjct 750 CKRYDKLPDEVDLNFDGMNLPQLVEMNYNSSETSDRIEVFPNYVIENTSDLANLTEIVKE 809
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESI-------KAYLKQAPPSKGP 523
GT T NL Y I V + K + +
Sbjct 810 VVVYGTTEVTL--PNLEHFSEYSIEVLACQDYNEKVLSKLCSIRAITFERTKDSYAADMI 867
Query 524 TVRTKKVG-----KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE---TAVNVDSSH- 574
T ++W+ NG I Y ++Y+ + +
Sbjct 868 NETTVDTEIETNFTGNVFIKWES--PTSPNGLILKYLLWYKKANQENLVPQTICITRQEY 925
Query 575 ---TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF----TTPKFAQGEIEAIVVPVCL 627
Y L+ L + +++A + F P IV V
Sbjct 926 LKNLGYKLTRLEPG-NWTFKISAISLAENSSFTLERFFIVPRPPDPESSNTLLIVAIVLA 984
Query 628 AFLLTTLLGVLFCFNKRDLIKK 649
F + T+ ++ C + I+
Sbjct 985 FFGVLTVSLIVACVYYKQKIRS 1006
Score = 42.5 bits (98), Expect = 0.020, Method: Composition-based stats.
Identities = 17/78 (22%), Positives = 29/78 (37%), Gaps = 4/78 (5%)
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDP--VYKVKPNPPHNLSVINSEELSSILKLT 243
Y F V+++A + N Y P+ P +L I+ + L+++
Sbjct 596 YDLKPFTTYAVYIQAYTVSTATHAAMTNILTFTTYPFHPSEPTDLVAISED--PHELRVS 653
Query 244 WTNPSIKSVIILKYNIQY 261
W P + I Y I Y
Sbjct 654 WKPPKYPNGNITHYKIVY 671
>sp|Q05623|MYBPH_CHICK Myosin-binding protein H OS=Gallus gallus
OX=9031 GN=MYBPH PE=1 SV=1
Length=537
Score = 72.6 bits (176), Expect = 9e-12, Method: Composition-based stats.
Identities = 54/290 (19%), Positives = 97/290 (33%), Gaps = 27/290 (9%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIIL-KYNIQYRTKDASTWSQIPPEDTASTRSS 283
P +L+V E S + LTW P L Y ++ ++ W+ + E STR
Sbjct 138 PLSLAVEEVTENS--VTLTWKAPEHTGKSSLDGYVVEICKDGSTDWTAVNKEPFLSTR-- 193
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSFWYKIDPSHTQ 342
+ + DL + R++ + G + + D P + P ++ H
Sbjct 194 YKIHDLASGEKVHVRVKAISASGTSDPATLEQPVLIREITDLPRIRLPRQLRQVYVRHVG 253
Query 343 GYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN------ATKLTVNL--TND 394
+ + ++ P +VT T+ L VN T + +D
Sbjct 254 EAVNLLIPFQGKPQP---------QVTWTKDNQPLDTSRVNIRNTDKDTIFFIRTAQRSD 304
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM-LWVEWTTPRESVKKY 453
L+VR + G D A+L I + P +LK + +EW+ P ++
Sbjct 305 SGKYQLSVR-INGAEDKAILDIRVIERPG--PPQNLKLVDVWGFNVALEWSPPADNGNSE 361
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADG 503
I + V + + + +L Y V A G
Sbjct 362 IKGYTVQKSDKKSGKWFTVLERCTRTSCTISDLIIGNTYSFRVFSENACG 411
Score = 68.3 bits (165), Expect = 2e-10, Method: Composition-based stats.
Identities = 56/337 (17%), Positives = 94/337 (28%), Gaps = 39/337 (12%)
Query 346 TVQLVWKTLPPFEANGKILDYEVTLTRWKSH----LQNYTVNATKLTVNLT--NDRYLAT 399
+V L WK P + Y V + + S + +T+ ++ ++
Sbjct 150 SVTLTWKA-PEHTGKSSLDGYVVEICKDGSTDWTAVNKEPFLSTRYKIHDLASGEKVHVR 208
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
+ + G SD A L P + T ++ + ++V E+V I
Sbjct 209 VKAISASGTSDPATLEQPVLIREITDLPR-IRLPRQLRQVYVR--HVGEAVNLLI----P 261
Query 460 LSDKAPCITDWQQED-GTVHRTYLRGNLAESKCYLITVTPVYADG-PGSPESIKAYLKQA 517
K W +++ N + + I G I +A
Sbjct 262 FQGKPQPQVTWTKDNQPLDTSRVNIRNTDKDTIFFIRTAQRSDSGKYQLSVRINGAEDKA 321
Query 518 --------PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT-IIGNETAV 568
P ++ V LEW P D N I+ YT+ G V
Sbjct 322 ILDIRVIERPGPPQNLKLVDVWGFNVALEWSP-PADNGNSEIKGYTVQKSDKKSGKWFTV 380
Query 569 NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF-------------TTPKFAQ 615
+ T T+S L Y R+ + G + P+
Sbjct 381 LERCTRTSCTISDLIIGNTYSFRVFSENACGMSETAAVAAGVAHIKKTVYQPQKIPERDM 440
Query 616 GEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIW 652
E P+ LFC + K IW
Sbjct 441 MEPPKFTQPLTDRATTRGYSTHLFCSVRGFPQPKIIW 477
Score = 59.1 bits (141), Expect = 1e-07, Method: Composition-based stats.
Identities = 25/98 (26%), Positives = 40/98 (41%), Gaps = 6/98 (6%)
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTKDAST 268
D D +P PP NL +++ + + L W+ P+ + I Y +Q K +
Sbjct 319 DKAILDIRVIERPGPPQNLKLVDVWGFN--VALEWSPPADNGNSEIKGYTVQKSDKKSGK 376
Query 269 WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
W + TR+S T+ DL Y FR+ G
Sbjct 377 WFTVLER---CTRTSCTISDLIIGNTYSFRVFSENACG 411
Score = 44.5 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 28/168 (17%), Positives = 58/168 (35%), Gaps = 7/168 (4%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTF--TDIASLNIQLTCNILTFGQLEQ 113
+ + W ++ + + I N ++ F T S + + ++ G ++
Sbjct 261 PFQGKPQPQVTWTKDNQPLDTSRVNIRNTDKDTIFFIRTAQRSDSGKYQLSVRINGAEDK 320
Query 114 NVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN--FTLKSEWATHKFAD 171
+ I +I P P+NL + G + EW + +T++
Sbjct 321 AILDIRVIER--PGPPQNLKLVDVWGFNVALEWSPPADNGNSEIKGYTVQKSDKKSGKWF 378
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYK 219
+R T TSCT+ + V +ENA G + + +
Sbjct 379 TVLERCTRTSCTIS-DLIIGNTYSFRVFSENACGMSETAAVAAGVAHI 425
Score = 39.5 bits (90), Expect = 0.14, Method: Composition-based stats.
Identities = 20/85 (24%), Positives = 33/85 (39%), Gaps = 3/85 (4%)
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDSS-HTEY 577
S ++ ++V +N L W P + Y + + + TAVN + T Y
Sbjct 136 SVPLSLAVEEVTENSVTLTWKA-PEHTGKSSLDGYVVEICKDGSTDWTAVNKEPFLSTRY 194
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKD 602
+ L S VR+ A + G D
Sbjct 195 KIHDLASGEKVHVRVKAISASGTSD 219
Score = 38.7 bits (88), Expect = 0.30, Method: Composition-based stats.
Identities = 41/298 (14%), Positives = 92/298 (31%), Gaps = 25/298 (8%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETN--FTLKSEWATHKFADCKAKRDTPTSCTV 184
P +L+ + W T + + ++ K ++
Sbjct 136 SVPLSLAVEEVTENSVTLTWKAPEHTGKSSLDGYVVEICKDGSTDWTAVNKEPFLSTRYK 195
Query 185 DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ + V V+A +A G + + + + P I + +
Sbjct 196 IHDLASGEKVHVRVKAISASGTSDPATLEQPVLIREITDLPR----IRLPRQLRQVYVR- 250
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ + L Q + + TW++ ++ S +++ T + R +
Sbjct 251 ---HVGEAVNLLIPFQGKPQPQVTWTK---DNQPLDTSRVNIRNTDKDTIFFIRTAQRSD 304
Query 305 DGKGYWS---DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
GK S + +E+ + + P K+ V L W P N
Sbjct 305 SGKYQLSVRINGAEDKAILDIRVIERPGPPQNLKLVDVW---GFNVALEWSP-PADNGNS 360
Query 362 KILDYEVTLT-----RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVL 414
+I Y V + +W + L+ T + ++ + + Y + N G S+ A +
Sbjct 361 EIKGYTVQKSDKKSGKWFTVLERCTRTSCTISDLIIGNTYSFRVFSENACGMSETAAV 418
>sp|Q5ZQU0|SNED1_RAT Sushi, nidogen and EGF-like domain-containing
protein 1 OS=Rattus norvegicus OX=10116 GN=Sned1 PE=2 SV=2
Length=1403
Score = 73.0 bits (177), Expect = 1e-11, Method: Composition-based stats.
Identities = 42/296 (14%), Positives = 82/296 (28%), Gaps = 38/296 (13%)
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY 380
T E P A V + W A + Y VT +
Sbjct 903 TKELLPPTALRVERV-------EESGVSISWSPPEGTTARQVLDGYAVTYASSDGSSRRT 955
Query 381 -----TVNATKLTVNLTNDRYLATL--TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF 433
+ ++ +L Y ++ RN K+D + +
Sbjct 956 DFVDRSRSSHQLRALAAGRAYNISVFSVKRNTNNKNDISRPAALLTRTRPRPIEDFEVTN 1015
Query 434 PKDNMLWVEW-----TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
N + V+W S + + + + + D +V R G+L
Sbjct 1016 ISANAISVQWALHRIQHATVSRVRVSVLY-----PEDTVVQSTEVDRSVDR-LTFGDLLP 1069
Query 489 SKCYLITVTPVYADGPG-------SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
+ Y + +T + G + + + + PP+ + +V A + WD
Sbjct 1070 GRRYSVRLTTLSGPGGAEYPTESLASAPLNVWTRPLPPA---NLTASRVTATSAHMVWDP 1126
Query 542 LPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
+ Y I T ++ + YT+ L Y + + A
Sbjct 1127 P---TPGISLEAYVINVTTSQNTKSRYIPNGKLVSYTVRDLMPGRRYQLSVTAVQS 1179
Score = 69.1 bits (167), Expect = 2e-10, Method: Composition-based stats.
Identities = 57/327 (17%), Positives = 105/327 (32%), Gaps = 27/327 (8%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKS--VIILKYNIQYRTKDASTWSQIPPEDTAST 280
PP L V EE + ++W+ P + ++ Y + Y + D S+ + +
Sbjct 907 LPPTALRVERVEESG--VSISWSPPEGTTARQVLDGYAVTYASSDGSSRRT---DFVDRS 961
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
RSS ++ L Y + +K + +D S A+ +T RP F
Sbjct 962 RSSHQLRALAAGRAYNISVFSVKRNTNNK-NDISRPAALLT-RTRPRPIEDFEV-----T 1014
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTR---WKSHLQNYTVNATKLTVNLTNDRYL 397
+ + W A + V +S + +V+ L RY
Sbjct 1015 NISANAISVQWALHRIQHATVSRVRVSVLYPEDTVVQSTEVDRSVDRLTFGDLLPGRRYS 1074
Query 398 ATLTVRNLVGKSDAAVLTIPACDF----QATHPVMDLKAFPKDNMLWVEWTTPRESVKKY 453
LT + G ++ ++ + + P + + W P
Sbjct 1075 VRLTTLSGPGGAEYPTESLASAPLNVWTRPLPPANLTASRVTATSAHMVWDPP---TPGI 1131
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPV--YADGPGSPESIK 511
LE V++ T + +Y +L + Y ++VT V G E
Sbjct 1132 SLEAYVINVTTSQNTKSRYIPNGKLVSYTVRDLMPGRRYQLSVTAVQSTEQGQLHSEPAH 1191
Query 512 AYLKQAPPSKGPTVRTKKVGKNEAVLE 538
Y+ P G R + G + +L
Sbjct 1192 LYII-TSPRDGTDRRWHQGGHHSRMLR 1217
Score = 63.0 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 71/441 (16%), Positives = 138/441 (31%), Gaps = 58/441 (13%)
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL-EWCVLSDKAPCITDWQQEDG 475
C + P +++ + + W+ P + + +L + V + +
Sbjct 900 KDCTKELLPPTALRVERVEESGVSISWSPPEGTTARQVLDGYAVTYASSDGSSRRTDFVD 959
Query 476 TVHRTYLRGNLAESKCYLITV----TPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
++ LA + Y I+V S + A L + P +
Sbjct 960 RSRSSHQLRALAAGRAYNISVFSVKRNTNNKNDISRPA--ALLTRTRPRPIEDFEVTNIS 1017
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN---VDSSHTEYTLSSLTSDTLY 588
N ++W + + + +T V VD S T L Y
Sbjct 1018 ANAISVQW----ALHRIQHATVSRVRVSVLYPEDTVVQSTEVDRSVDRLTFGDLLPGRRY 1073
Query 589 MVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIK 648
VR+ + GG + P T A + P+ A L + +
Sbjct 1074 SVRLTTLSGPGGAEYP-----TESLASAPLNVWTRPLPPANLTASRVTATS--------A 1120
Query 649 KHIWPNVPDPSKS----------HIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEA 698
+W + P P S S + P + + G +SV +++
Sbjct 1121 HMVW-DPPTPGISLEAYVINVTTSQNTKSRYIPNGKLVSYTVRDLMPGRRYQLSVTAVQS 1179
Query 699 NDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPS------ISSSDENESSQN 752
++ + L + + T+ G S M +RP+ + +++ + +
Sbjct 1180 TEQGQLHSEPAHLYIITSPRDGTDRRWHQGGHHSRMLRNRPAPLRLPELRLLNDHGAPET 1239
Query 753 TSSTVQYSTVVHSGYRHQ-----VPSVQVFSRSESTQPL-LDSEERPEDLQLVDHVDGGD 806
+ ++S +V R +PS V RS+ T P+ L + E PE +L
Sbjct 1240 PTQPPRFSELVDGRARVSARFGGLPSRAVTVRSQPTTPVPLKNTEAPEQARLALQ----- 1294
Query 807 GILPRQQYFKQNCSQHESSPD 827
LP+ K S S +
Sbjct 1295 --LPKNNS-KDTESTPGSCSE 1312
Score = 47.9 bits (112), Expect = 5e-04, Method: Composition-based stats.
Identities = 22/126 (17%), Positives = 43/126 (34%), Gaps = 12/126 (10%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
AE + S +N +P PP NL+ ++ + W P+ +
Sbjct 1086 AEYPTESLASAPLNVWT----RPLPPANLTASRV--TATSAHMVWDPPTPGISLE----- 1134
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW-SDWSEEAS 318
Y ++ + S+TV+DL P Y + ++ +G S+ +
Sbjct 1135 AYVINVTTSQNTKSRYIPNGKLVSYTVRDLMPGRRYQLSVTAVQSTEQGQLHSEPAHLYI 1194
Query 319 GITYED 324
+ D
Sbjct 1195 ITSPRD 1200
>sp|Q9U4G1|BDL_DROME Protein borderless OS=Drosophila melanogaster
OX=7227 GN=bdl PE=1 SV=1
Length=719
Score = 72.6 bits (176), Expect = 1e-11, Method: Composition-based stats.
Identities = 54/326 (17%), Positives = 99/326 (30%), Gaps = 43/326 (13%)
Query 387 LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
+T + DR + + N + A +L A + + + W
Sbjct 400 ITGLVEGDRGIYECSATNEAAT--ITAEAELMIENIAPRAPYNLTANSTETCITIRWQPG 457
Query 447 RESVKKYILEWCVLSD--KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
LE+ V +AP + D V +L K Y V G
Sbjct 458 YLRPN---LEYTVWYRLMEAPEWRTLRVLDKKVMEA-TVQHLQPGKEYEFMVLSQDKYGD 513
Query 505 GS----------PESIKAY------LKQ-----APPS----KGPTVRTKKVGKNEAVLEW 539
G P I+A L+ P+ + + L W
Sbjct 514 GMFSKQFRFQTLPSPIRADDFDAQQLQHDLGQVTAPAGGLGAPWNLTAISNQQGWL-LHW 572
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ PV G +R Y + + + + ++ Y L L DTL+ V++ A E
Sbjct 573 EH-PVQGLEG-LRLYAVRWWKEPEHFLIGHAETFDNYYQLRHLKEDTLFKVQVLAVGTET 630
Query 600 GKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPS 659
+ P +Q ++ A+++ + + F + KR ++ +
Sbjct 631 QQSVPSHELLIDVPSQRKVRALIIGSSVGVIFLLCALCAFLYVKRSCLRHLF-------A 683
Query 660 KSHIAQWSPHTPPRHNFNSKDQMYSD 685
K A T + +S +Q D
Sbjct 684 KDSSASEDEDTAESGDCDSDEQDQRD 709
Score = 70.7 bits (171), Expect = 4e-11, Method: Composition-based stats.
Identities = 36/181 (20%), Positives = 64/181 (35%), Gaps = 36/181 (20%)
Query 217 VYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPED 276
+ + P P+NL+ ++E + + + W ++ L+Y + YR +A W + D
Sbjct 430 IENIAPRAPYNLTANSTE---TCITIRWQPGYLR--PNLEYTVWYRLMEAPEWRTLRVLD 484
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE------------- 323
TVQ L+P EY F + + G G +S + T
Sbjct 485 --KKVMEATVQHLQPGKEYEFMVLSQDKYGDGMFSK---QFRFQTLPSPIRADDFDAQQL 539
Query 324 -------DRPSKAP-SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
P+ + W S+ QG+ L W+ P + + Y V +
Sbjct 540 QHDLGQVTAPAGGLGAPWNLTAISNQQGW---LLHWEH--PVQGLEGLRLYAVRWWKEPE 594
Query 376 H 376
H
Sbjct 595 H 595
>sp|O60500|NPHN_HUMAN Nephrin OS=Homo sapiens OX=9606 GN=NPHS1
PE=1 SV=1
Length=1241
Score = 72.6 bits (176), Expect = 1e-11, Method: Composition-based stats.
Identities = 37/220 (17%), Positives = 66/220 (30%), Gaps = 20/220 (9%)
Query 132 LSCIVNEGKKMRCEW--DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
L C + W +G + +T + + + +
Sbjct 861 LHCRARGVPNIVFTWTKNGVPLDLQDPRYTEHTYHQGGVHSSLLTIANVSAAQDYAL--- 917
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
A NALG SD N V +P+PP L V++ + L W P
Sbjct 918 ------FTCTATNALG---SDQTNIQLVSISRPDPPSGLKVVSL--TPHSVGLEWK-PGF 965
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ ++ I+Y + + ++FT+ L+P T Y + G
Sbjct 966 DGGLPQRFCIRYEALGTPGFHYVDV--VPPQATTFTLTGLQPSTRYRVWLLASNALGDSG 1023
Query 310 WSDWSEEASGITY-EDRPSKAPSFWYKIDPSHTQGYRTVQ 348
+D + T +PS P +P +
Sbjct 1024 LADKGTQLPITTPGLHQPSGEPEDQLPTEPPSGPSGLPLL 1063
Score = 60.6 bits (145), Expect = 7e-08, Method: Composition-based stats.
Identities = 38/235 (16%), Positives = 72/235 (31%), Gaps = 22/235 (9%)
Query 31 ISPESPVVQLH------SNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINR 84
+ +P+ ++ S+ T C + F N + + Y
Sbjct 840 VEHPTPLTKVAAAGDSTSSATLHCRARGVPNIVFTWTKNGVPLDLQDPRYTEHTYHQGGV 899
Query 85 TASSVTFTDIASLN--IQLTCNILT-FGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKK 141
+S +T ++++ TC G + N+ ++I P+ P L +
Sbjct 900 HSSLLTIANVSAAQDYALFTCTATNALGSDQTNIQLVSISR---PDPPSGLKVVSLTPHS 956
Query 142 MRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAE 201
+ EW G + L F ++ E + VW+ A
Sbjct 957 VGLEWKPGFDGGLPQRFCIRYEALGTPGFHYVDVVPPQATTFTLTGLQPSTRYRVWLLAS 1016
Query 202 NALG-KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
NALG +D P+ + P ++L + PS S + L
Sbjct 1017 NALGDSGLADKGTQLPITTPGLHQPSG---EPEDQLPT------EPPSGPSGLPL 1062
Score = 58.7 bits (140), Expect = 3e-07, Method: Composition-based stats.
Identities = 37/183 (20%), Positives = 61/183 (33%), Gaps = 13/183 (7%)
Query 450 VKKYILEWC----VLSDKAPCITDWQQEDGTVHRTYL-RGNLAESKCY-LITVTPVYADG 503
V + W L + P T+ G VH + L N++ ++ Y L T T A
Sbjct 868 VPNIVFTWTKNGVPLDLQDPRYTEHTYHQGGVHSSLLTIANVSAAQDYALFTCTATNA-- 925
Query 504 PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
GS ++ + + P ++ + + LEW G + + I Y +
Sbjct 926 LGSDQTNIQLVSISRPDPPSGLKVVSLTPHSVGLEW---KPGFDGGLPQRFCIRYEALGT 982
Query 564 NETAVN--VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAI 621
V T +TL+ L T Y V + A G + P G +
Sbjct 983 PGFHYVDVVPPQATTFTLTGLQPSTRYRVWLLASNALGDSGLADKGTQLPITTPGLHQPS 1042
Query 622 VVP 624
P
Sbjct 1043 GEP 1045
>sp|Q16827|PTPRO_HUMAN Receptor-type tyrosine-protein phosphatase
O OS=Homo sapiens OX=9606 GN=PTPRO PE=1 SV=2
Length=1216
Score = 72.6 bits (176), Expect = 1e-11, Method: Composition-based stats.
Identities = 71/495 (14%), Positives = 143/495 (29%), Gaps = 64/495 (13%)
Query 135 IVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNI 194
+M W + F + E F + + +
Sbjct 338 FSFFPVQMILTWLPPKPPTAFDGFHIHIE-REENFTEYLMVDEEAHEFVAELKEPG--KY 394
Query 195 EVWVEAENALGK--------VTSDHINFDPVYK---VKPNPPHNLSVINSEELSSILKLT 243
++ V ++ G S P + P ++SV S+ ++
Sbjct 395 KLSVTTFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTEKPQHVSVHVL--SSTTALMS 452
Query 244 WTNPSIK-SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
WT+ + I+ K + T S +++L P +Y I
Sbjct 453 WTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLR 512
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
K G SD +T+ P+ G V L W G
Sbjct 513 KGPLIGPPSDP------VTFAIVPTGIKDLMLY-----PLGPTAVVLSWTRP----YLGV 557
Query 363 ILDYEVTL---------TRWKSHLQ---NYTVNATKLTVNLTN-DRYLATLTVRNLVGKS 409
Y V + + W ++ + ++ A+ NL Y +T+
Sbjct 558 FRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPE 617
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK---KYILEWCVLSDKAPC 466
+ + A +++L++ WT ++ +L W V+++
Sbjct 618 LSCCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKK 677
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVR 526
I + V L L Y ++VT G + L + P+ ++
Sbjct 678 IK--KSVTRNVMTAILS--LPPGDIYNLSVTACTERG---SNTSMLRLVKLEPAPPKSLF 730
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV---NVDSSHTEYTLSSLT 583
+ L W + G + +F + + ++ V S T+SSL
Sbjct 731 AVNKTQTSVTLLWVE------EGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTISSLL 784
Query 584 SDTLYMVRMAAYTDE 598
T Y + +++ +
Sbjct 785 PATAYNCSVTSFSHD 799
Score = 61.4 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 67/421 (16%), Positives = 125/421 (30%), Gaps = 42/421 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA--THKFADCKAKRDTPTSCTV 184
EKP+++S V W +E + T ++ S + + + T + +
Sbjct 434 EKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSK 493
Query 185 DYSTVYFVNIEVWVEAENALGKV---TSDHINFDPVYKVKPNPPHNLS-VINSEELSSIL 240
+ V G + SD + F V P + ++ + +
Sbjct 494 PIIENLVPGAQYQVVIYLRKGPLIGPPSDPVTFAIV-------PTGIKDLMLYPLGPTAV 546
Query 241 KLTWTNPSIKSVIILKYNIQ---YRTKD-ASTWSQ-IPPEDTASTRSSFTVQDLKPFTEY 295
L+WT P + + KY ++ + S W+ T S +S + +L P Y
Sbjct 547 VLSWTRPYL--GVFRKYVVEMFYFNPATMTSEWTTYYEIAATVSLTASVRIANLLPAWYY 604
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ-LVWKTL 354
FR+ + S S IT P + + + + ++ + W
Sbjct 605 NFRVTMVTWGDPELSCCDSSTISFITAPVAP----------EITSVEYFNSLLYISWTYG 654
Query 355 PPFEAN--GKILDYEVTLTRWKSHLQNYTVNA-TKLTVNLTNDRYLATLTVRNLVGKSDA 411
++L + V K ++ T N T + D Y ++T G +
Sbjct 655 DDTTDLSHSRMLHWMVVAEGKKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERG---S 711
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
+ + P + + W E V + +C T Q
Sbjct 712 NTSMLRLVKLEPAPPKSLFAVNKTQTSVTLLW--VEEGVADFFEVFCQQVGS-SQKTKLQ 768
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
+ +L + Y +VT D P P I P V V
Sbjct 769 EPVAVSSHVVTISSLLPATAYNCSVTSFSHDSPSVPTFIAVST--MVTEMNPNVVVISVL 826
Query 532 K 532
Sbjct 827 A 827
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 61/378 (16%), Positives = 118/378 (31%), Gaps = 32/378 (8%)
Query 242 LTWTNPSIKSVIILKYNIQY-RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
LTW P ++I R ++ + + + E + V +LK +Y +
Sbjct 347 LTWLPP-KPPTAFDGFHIHIEREENFTEYLMVDEE------AHEFVAELKEPGKYKLSVT 399
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ----GYRTVQLVWKTLPP 356
G + S+ A +++ PS P H T + W +
Sbjct 400 TFSSSGSCE-TRKSQSAKSLSFYISPSGEWIEELTEKPQHVSVHVLSSTTALMSWTS-SQ 457
Query 357 FEANGKILDYEVTLTRWKSHLQN-------YTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
N I+ V+LT K VN++K + + + G
Sbjct 458 ENYNSTIVS-VVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVVIYLRKGP- 515
Query 410 DAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESV-KKYILE--WCVLSDKAP 465
+ P + DL +P + + WT P V +KY++E + +
Sbjct 516 LIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATMTS 575
Query 466 CITDWQQEDGTV--HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
T + + TV + NL + Y VT V P + + P
Sbjct 576 EWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP 635
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT-LSSL 582
+ + + + + W R + + + + + + T + SL
Sbjct 636 EITSVEYFNSLLYISWTYGDDTTDLSHSR--MLHWMVVAEGKKKIKKSVTRNVMTAILSL 693
Query 583 TSDTLYMVRMAAYTDEGG 600
+Y + + A T+ G
Sbjct 694 PPGDIYNLSVTACTERGS 711
>sp|Q9JIR1|RIMB2_RAT RIMS-binding protein 2 OS=Rattus norvegicus
OX=10116 GN=Rimbp2 PE=1 SV=2
Length=1049
Score = 72.6 bits (176), Expect = 1e-11, Method: Composition-based stats.
Identities = 50/372 (13%), Positives = 108/372 (29%), Gaps = 53/372 (14%)
Query 129 PKNLSCIVNEGKKMRCEWDGGRET---HLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P+ ++ I K + W+ +++ + + T + ++
Sbjct 297 PRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMSLALGRRTKAL----IE 352
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ V+ + G V P L V N ++S+ +L+W
Sbjct 353 KLNTAACTYRISVQCVTSRGNSDELQCTLLVGKDVVV-APSQLRVDNITQISA--QLSW- 408
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P+ + + + ++ + + R + +L+P Y ++
Sbjct 409 LPTNSNYSHIIFL-----------NEEELDIVKAARYKYQFFNLRPNMAYKVKVLAQPHQ 457
Query 306 GKGYWSDWSEEASG----ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL---PPFE 358
W E+ + + P+ P+ + +VQ+ WK P
Sbjct 458 M--PWQLPLEQREKDEACVEFSTLPAGPPAPPQDVTVQAGATTASVQVSWKPPALTPTGL 515
Query 359 ANG-KILDYEVTLTRWKSHLQNYTVNATKLTVNLTN----DRYLATLTVRNLVGKS---- 409
+NG + Y V + + + A V L + ++ + G+S
Sbjct 516 SNGANVTGYGV-YAKGQRVAEVIAPTANGAAVELVRLRSLEAKAVSVRTLSAQGESMDSA 574
Query 410 ----DAAVLTIPACDFQATHPV------MDLKAFPKDNMLWVEWT--TPRESVKKYILEW 457
+L PA + P MD K + W P ++LE
Sbjct 575 LAAIPPDLLVPPAPHPRTAPPPKPLTSDMDTKDLGPHVKVDESWEQSRPPGPAHGHMLEP 634
Query 458 CVLSDKAPCITD 469
+ P
Sbjct 635 PDMHSTGPGRRS 646
Score = 64.5 bits (155), Expect = 4e-09, Method: Composition-based stats.
Identities = 41/275 (15%), Positives = 76/275 (28%), Gaps = 28/275 (10%)
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLT 401
Q ++V + W+ G + Y V + + L L ++
Sbjct 305 QLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMSLALGRRTKALIEKLNTAACTYRIS 364
Query 402 V--RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
V G SD T+ P + W P S +I+
Sbjct 365 VQCVTSRGNSDELQCTLLVGKDVVVAPSQLRVDNITQISAQLSW-LPTNSNYSHII---F 420
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA-- 517
L+++ I + Y NL + Y + V P + +A
Sbjct 421 LNEEELDIVKAAR------YKYQFFNLRPNMAYKVKVLAQPHQMPWQLPLEQREKDEACV 474
Query 518 --------PPSKGPTVRTKK-VGKNEAVLEWDQL---PVDVQNG-FIRNYTIFYRTIIGN 564
PP+ V + + W P + NG + Y ++ +
Sbjct 475 EFSTLPAGPPAPPQDVTVQAGATTASVQVSWKPPALTPTGLSNGANVTGYGVYAKGQRVA 534
Query 565 ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
E + ++ L L S V + + +G
Sbjct 535 EV-IAPTANGAAVELVRLRSLEAKAVSVRTLSAQG 568
Score = 52.2 bits (123), Expect = 3e-05, Method: Composition-based stats.
Identities = 43/342 (13%), Positives = 93/342 (27%), Gaps = 47/342 (14%)
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS--VIILKYNIQYRTKDASTW 269
++ + + P+ + ++L+ + + W P++ + YN+
Sbjct 282 LDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNV-------LVD 334
Query 270 SQIPPEDTASTRSSFTVQDLK-PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP-S 327
+ R+ ++ L Y ++C+ G S+E +
Sbjct 335 KETRMSLALGRRTKALIEKLNTAACTYRISVQCVTSRGN------SDELQCTLLVGKDVV 388
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKL 387
APS + + + QL W LP I + L + + +
Sbjct 389 VAPSQLRVDNITQI----SAQLSW--LPTNSNYSHI----IFLNEEELDIVKAARYKYQF 438
Query 388 TVNLTNDRYLATLTVRN---------LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN- 437
N Y + + + D A + P D+
Sbjct 439 FNLRPNMAYKVKVLAQPHQMPWQLPLEQREKDEACVEFSTLPAGPPAPPQDVTVQAGATT 498
Query 438 -MLWVEWTTPRESVKKY-----ILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESK 490
+ V W P + + + V + + T + + L +
Sbjct 499 ASVQVSWKPPALTPTGLSNGANVTGYGVYAKGQRVA---EVIAPTANGAAVELVRLRSLE 555
Query 491 CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGK 532
++V + A G ++ A P RT K
Sbjct 556 AKAVSVRTLSAQGESMDSALAAIPPDLLVPPAPHPRTAPPPK 597
Score = 39.5 bits (90), Expect = 0.18, Method: Composition-based stats.
Identities = 15/108 (14%), Positives = 39/108 (36%), Gaps = 6/108 (6%)
Query 497 TPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
+ + +G G+ + + + + K ++ W+ V G + +Y +
Sbjct 272 SGITDNGGGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNV 331
Query 557 FYRTIIGNETAVNVD-SSHTEYTLSSLTSDT-LYMVRMAAYTDEGGKD 602
++ ET +++ T+ + L + Y + + T G D
Sbjct 332 ----LVDKETRMSLALGRRTKALIEKLNTAACTYRISVQCVTSRGNSD 375
>sp|P08575|PTPRC_HUMAN Receptor-type tyrosine-protein phosphatase
C OS=Homo sapiens OX=9606 GN=PTPRC PE=1 SV=3
Length=1306
Score = 72.2 bits (175), Expect = 2e-11, Method: Composition-based stats.
Identities = 53/335 (16%), Positives = 100/335 (30%), Gaps = 34/335 (10%)
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR------WKSHL 377
D P F + T+ L WK + F + + + Y
Sbjct 298 DVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNITYRFQCGNMIFDNKEIKLE 357
Query 378 QNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN 437
+ K + + + T + I P + +
Sbjct 358 NLEPEHEYKCDSEILYNNHKFTNASK-----------IIKTDFGSPGEPQIIFCRSEAAH 406
Query 438 MLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
+ W P+ S + L + ++K D D + + L+ NL Y++++
Sbjct 407 QGVITWNPPQRSFHNFTLCYIKETEK-----DCLNLDKNLIKYDLQ-NLKPYTKYVLSLH 460
Query 498 PVYADGP---GSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
GS K APPS+ + N ++ P +NG Y
Sbjct 461 AYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVK--CRPPRDRNGPHERY 518
Query 555 TIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFA 614
+ GN N + ++ + L T Y AY G G F
Sbjct 519 HLEVEA--GNTLVRNESHKNCDFRVKDLQYSTDYTF--KAYFHNGDYPG--EPFILHHST 572
Query 615 QGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKK 649
+A++ + ++T++ ++ + DL KK
Sbjct 573 SYNSKALIAFLAFLIIVTSIALLVVLYKIYDLHKK 607
Score = 52.2 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 39/272 (14%), Positives = 79/272 (29%), Gaps = 32/272 (12%)
Query 54 CMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQ 113
C + + N T + I R D + ++ + +
Sbjct 311 CTQVEKADTTICLKWKNIETFTCDTQNITYRFQCGNMIFDNKEIKLENLEPEHEYKCDSE 370
Query 114 NVYGITIISGLP---------PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEW 164
+Y + P +P+ + C + W+ + + NFTL
Sbjct 371 ILYNNHKFTNASKIIKTDFGSPGEPQIIFCRSEAAHQGVITWNPPQRSFH--NFTLCYIK 428
Query 165 ATHKFADCKA------KRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVY 218
T K DC K D + + N S +
Sbjct 429 ETEK--DCLNLDKNLIKYDLQNLKPYTKYVLSLHAYIIAKVQRNG-----SAAMCHFTTK 481
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
P+ N++V + + S +K P ++ +Y+++ + ++ +
Sbjct 482 SAPPSQVWNMTVSMTSDNSMHVKC--RPPRDRNGPHERYHLEVEAGNTLVRNE------S 533
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
F V+DL+ T+Y F+ D G
Sbjct 534 HKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEP 565
Score = 46.8 bits (109), Expect = 0.001, Method: Composition-based stats.
Identities = 27/162 (17%), Positives = 50/162 (31%), Gaps = 16/162 (10%)
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+TW P I+ ++ + + +Q+LKP+T+YV +
Sbjct 410 ITWNPPQRSFHNFTLCYIK--------ETEKDCLNLDKNLIKYDLQNLKPYTKYVLSLHA 461
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ S T + P PS + + S T + K PP + NG
Sbjct 462 Y--IIAKVQRNGSAAMCHFTTKSAP---PSQVWNMTVSMTSDNS---MHVKCRPPRDRNG 513
Query 362 KILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVR 403
Y + + + ++N + V T
Sbjct 514 PHERYHLEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAY 555
>sp|Q05688|IGF1R_BOVIN Insulin-like growth factor 1 receptor (Fragment)
OS=Bos taurus OX=9913 GN=IGF1R PE=2 SV=1
Length=640
Score = 71.4 bits (173), Expect = 2e-11, Method: Composition-based stats.
Identities = 35/214 (16%), Positives = 75/214 (35%), Gaps = 20/214 (9%)
Query 447 RESVKKYILEWCVLSDKAPCITDW---QQEDGTVHRTYLRGNLAESKCYLITVTPVYAD- 502
S +L+ ++D T++ + RT + NL Y I + +
Sbjct 25 SRSRNTTVLDTYNITDPEELETEYPFFESRVDNKERTVI-SNLRPFTLYRIDIHSCNHEA 83
Query 503 ---GPGSPESIKAYL--KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
G + + A + V + +N L+W + + NG I Y I
Sbjct 84 EKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPE--PENPNGLILMYEIK 141
Query 558 YRTIIGNETAVNVDSSHTEY---TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFA 614
Y + + ++ + +Y L+ L Y R+ A + G + F +
Sbjct 142 YGSQVEDQRECVSRQEYRKYGGAKLNRLNPG-NYTARIQATSLSGNGSWTDPVFFYVQAK 200
Query 615 QGE----IEAIVVPVCLAFLLTTLLGVLFCFNKR 644
I +P+ + ++ L+ +L+ F+++
Sbjct 201 TTYENFIHLMIALPIAVLLIVGGLVIMLYVFHRK 234
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 30/175 (17%), Positives = 53/175 (30%), Gaps = 15/175 (9%)
Query 147 DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN---- 202
R T + + + R TV + F + + + N
Sbjct 25 SRSRNTTVLDTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAE 84
Query 203 ALGKVTSDHINFDPV----YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
LG S+ + + P P V + + L W P + +IL Y
Sbjct 85 KLGCSASNFVFARTMPAEGADDIPGP-----VTWEPRPENSIFLKWPEPENPNGLILMYE 139
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
I+Y ++ + ++ + L P Y RI+ G G W+D
Sbjct 140 IKYGSQVEDQRECVSRQE-YRKYGGAKLNRLNPG-NYTARIQATSLSGNGSWTDP 192
Score = 50.6 bits (119), Expect = 6e-05, Method: Composition-based stats.
Identities = 27/157 (17%), Positives = 44/157 (28%), Gaps = 13/157 (8%)
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
E + + +L+PFT Y I + + S T P++
Sbjct 52 ESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTM---PAEGADDIP 108
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL-------TRWKSHLQNYTVNATKL 387
+ ++ L W P NG IL YE+ S + KL
Sbjct 109 GPVTWEPRPENSIFLKW--PEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKL 166
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
+ Y A + +L G + T
Sbjct 167 NRLNPGN-YTARIQATSLSGNGSWTDPVFFYVQAKTT 202
>sp|H0UZ81|FSD2_CAVPO Fibronectin type III and SPRY domain-containing
protein 2 OS=Cavia porcellus OX=10141 GN=FSD2 PE=2 SV=2
Length=719
Score = 71.8 bits (174), Expect = 2e-11, Method: Composition-based stats.
Identities = 37/212 (17%), Positives = 67/212 (32%), Gaps = 24/212 (11%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
+ P+ P + S +++ W+ + +V Y + YR S + E T
Sbjct 339 ILAPSAPVINPQAPNSATGSSVRVCWSLYADDTVE--SYQLSYRPVRDSLPGKEQAEFTV 396
Query 279 STRSSF-TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
+ + S+ +V +L+P T+Y F + G S SE A +T PS
Sbjct 397 TVKESYCSVTNLEPNTQYEFWVIAQNRAG---PSPSSEHAMYMT---APSPP----IIKT 446
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT----RWKSHLQNYTVNATKLTVNL-- 391
+ + W++ + Y V LT S + V +
Sbjct 447 EAIRSCEEAALICWESGNLN----PVDSYTVELTQVEEPAASGVTESVVGIPICESLIQL 502
Query 392 -TNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
Y + N+ G S +
Sbjct 503 QPGQSYTICVRALNVGGPSARSTPATVRTTGS 534
Score = 64.5 bits (155), Expect = 4e-09, Method: Composition-based stats.
Identities = 33/211 (16%), Positives = 65/211 (31%), Gaps = 23/211 (11%)
Query 411 AAVLTIPACDFQATHPVMDLKA--FPKDNMLWVEWTTPRESVKK-YILEWCVLSDKAPCI 467
++ + PV++ +A + + V W+ + + Y L + + D P
Sbjct 330 EQLMGSMNTILAPSAPVINPQAPNSATGSSVRVCWSLYADDTVESYQLSYRPVRDSLPGK 389
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
+ NL + Y V GP Y+ PS P ++T
Sbjct 390 EQAEFTVTVKESYCSVTNLEPNTQYEFWVIAQNRAGPSPSSEHAMYM--TAPS-PPIIKT 446
Query 528 KKVGK--NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN------ETAVNVDSSHTEYTL 579
+ + A++ W+ + +YT+ + E+ V + + L
Sbjct 447 EAIRSCEEAALICWE----SGNLNPVDSYTVELTQVEEPAASGVTESVVGIPICES---L 499
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
L Y + + A G T T
Sbjct 500 IQLQPGQSYTICVRALNVGG--PSARSTPAT 528
Score = 61.0 bits (146), Expect = 4e-08, Method: Composition-based stats.
Identities = 24/132 (18%), Positives = 42/132 (32%), Gaps = 10/132 (8%)
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
E WV A+N G S +Y P+PP + + W + ++
Sbjct 411 NTQYEFWVIAQNRAGPSPSSE---HAMYMTAPSPPI-IKTEAIRSCEEAALICWESGNLN 466
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
+ Y ++ + S + +Q L+P Y +R + G
Sbjct 467 --PVDSYTVELTQVEEPAASGVTESVVGIPICESLIQ-LQPGQSYTICVRALN---VGGP 520
Query 311 SDWSEEASGITY 322
S S A+ T
Sbjct 521 SARSTPATVRTT 532
Score = 56.4 bits (134), Expect = 1e-06, Method: Composition-based stats.
Identities = 18/123 (15%), Positives = 37/123 (30%), Gaps = 10/123 (8%)
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI-----IG 563
S+ L + P P + + W D + +Y + YR +
Sbjct 335 SMNTILAPSAPVINPQAP-NSATGSSVRVCWSLYADDT----VESYQLSYRPVRDSLPGK 389
Query 564 NETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVV 623
+ V + ++++L +T Y + A G E + I+ +
Sbjct 390 EQAEFTVTVKESYCSVTNLEPNTQYEFWVIAQNRAGPSPSSEHAMYMTAPSPPIIKTEAI 449
Query 624 PVC 626
C
Sbjct 450 RSC 452
Score = 46.0 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 28/197 (14%), Positives = 62/197 (31%), Gaps = 24/197 (12%)
Query 325 RPSKAPSFWYKIDPSHTQG--YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ---- 378
PS I+P +V++ W A+ + Y+++ + L
Sbjct 341 APSAP-----VINPQAPNSATGSSVRVCWS----LYADDTVESYQLSYRPVRDSLPGKEQ 391
Query 379 ---NYTVNATKLTVNLT--NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF 433
TV + +V N +Y + +N G S ++ + + +
Sbjct 392 AEFTVTVKESYCSVTNLEPNTQYEFWVIAQNRAGPSPSSEHAMY-MTAPSPPIIKTEAIR 450
Query 434 PKDNMLWVEWTT-PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
+ + W + V Y +E + + A + + ++ L + Y
Sbjct 451 SCEEAALICWESGNLNPVDSYTVELTQVEEPAASGVTESVVGIPICESLIQ--LQPGQSY 508
Query 493 LITVTPVYADGPGSPES 509
I V + GP + +
Sbjct 509 TICVRALNVGGPSARST 525
>sp|P35832|PTP99_DROME Tyrosine-protein phosphatase 99A OS=Drosophila
melanogaster OX=7227 GN=Ptp99A PE=2 SV=2
Length=1301
Score = 72.2 bits (175), Expect = 2e-11, Method: Composition-based stats.
Identities = 43/243 (18%), Positives = 70/243 (29%), Gaps = 17/243 (7%)
Query 368 VTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS---DAAVLTIPACDFQAT 424
V T S Q T + + + G DA D
Sbjct 112 VLGTAATSIEQQDQPPDVPATTLAFANAFPVPVAGEMGNGNGNYNDATPPYAAVDDNYVP 171
Query 425 HPVMDLKAFPKD-NMLWVEWTTPRESVKKYILEWCVLS-DKAPCITDWQQEDGTVHRTYL 482
+L N + + W P+ I + V + + T +
Sbjct 172 SKPQNLTILDVSANSITMSWHPPKNQ-NGAIAGYHVFHIHDNQTGVEIVKNSRNSVETLI 230
Query 483 R---GNLAESKCYLITVTPVYADGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
NL Y + V G P I PS V + +
Sbjct 231 HFELQNLRPYTDYRVIVKAFTTKNEGEPSDQIAQRTDVGGPSAPAIVNLTCHSQESITIR 290
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGN-ETAVNVDSS----HTEYTLSSLTSDTLYMVRMA 593
W + P + N I Y I R + + +++S T L +LT+++ Y V++A
Sbjct 291 WRR-PYEFYN-TIDFYIIKTRLAGQDTHRDIRINASAKELETAMILQNLTTNSYYEVKVA 348
Query 594 AYT 596
A T
Sbjct 349 AAT 351
Score = 65.6 bits (158), Expect = 2e-09, Method: Composition-based stats.
Identities = 41/247 (17%), Positives = 94/247 (38%), Gaps = 32/247 (13%)
Query 202 NALGK-VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQ 260
N G + P+ P NL++++ S + ++W P ++ I Y++
Sbjct 150 NGNGNYNDATPPYAAVDDNYVPSKPQNLTILDVSANS--ITMSWHPPKNQNGAIAGYHVF 207
Query 261 YRTKDASTWSQI-PPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ + + + ++ T F +Q+L+P+T+Y ++ +G SD
Sbjct 208 HIHDNQTGVEIVKNSRNSVETLIHFELQNLRPYTDYRVIVKAFTTKNEGEPSD------- 260
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT-RWKSHLQ 378
+ PS ++ + ++ + W+ P+E I Y + + +
Sbjct 261 QIAQRTDVGGPSAPAIVNLTC-HSQESITIRWR--RPYEFYNTIDFYIIKTRLAGQDTHR 317
Query 379 NYTVNATK-------LTVNLTNDRY------LATLTVRN----LVGKSDAAVLTIPACDF 421
+ +NA+ + NLT + Y AT +V N ++GK + + +
Sbjct 318 DIRINASAKELETAMILQNLTTNSYYEVKVAAATFSVINPKKIVLGKFSESRIIQLQPNC 377
Query 422 QATHPVM 428
+ P++
Sbjct 378 EKLQPLL 384
Score = 65.6 bits (158), Expect = 2e-09, Method: Composition-based stats.
Identities = 25/114 (22%), Positives = 40/114 (35%), Gaps = 7/114 (6%)
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT-- 575
PSK + V N + W P QNG I Y +F+ + +S ++
Sbjct 170 VPSKPQNLTILDVSANSITMSWH--PPKNQNGAIAGYHVFHIHDNQTGVEIVKNSRNSVE 227
Query 576 ---EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVC 626
+ L +L T Y V + A+T + + + AIV C
Sbjct 228 TLIHFELQNLRPYTDYRVIVKAFTTKNEGEPSDQIAQRTDVGGPSAPAIVNLTC 281
Score = 65.3 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 26/187 (14%), Positives = 57/187 (30%), Gaps = 9/187 (5%)
Query 123 GLPPEKPKNLSCIVNEGKKMRCEWDGGRETH----LETNFTLKSEWATHKFADCKAKRDT 178
P KP+NL+ + + W + + F + + ++
Sbjct 168 NYVPSKPQNLTILDVSANSITMSWHPPKNQNGAIAGYHVFHIHDNQTGVEIVK-NSRNSV 226
Query 179 PTSCTVDYSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
T + + + + V V+A + P+ P +++ + S
Sbjct 227 ETLIHFELQNLRPYTDYRVIVKAFTTKNEGEPSDQIAQRTDVGGPSAPAIVNLTCHSQES 286
Query 238 SILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV-QDLKPFTEYV 296
+ + W P I Y I+ R T I +A + + Q+L + Y
Sbjct 287 --ITIRWRRPYEFYNTIDFYIIKTRLAGQDTHRDIRINASAKELETAMILQNLTTNSYYE 344
Query 297 FRIRCMK 303
++
Sbjct 345 VKVAAAT 351
>sp|Q28589|INAR1_SHEEP Interferon alpha/beta receptor 1 OS=Ovis
aries OX=9940 GN=IFNAR1 PE=2 SV=1
Length=560
Score = 71.4 bits (173), Expect = 2e-11, Method: Composition-based stats.
Identities = 89/536 (17%), Positives = 168/536 (31%), Gaps = 48/536 (9%)
Query 226 HNLSVINSEE--LSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP-EDTASTRS 282
NL N E + L W + S +SV + ++ Y+ W ++P + S++
Sbjct 26 ANLKSENVEIHIIDDNFFLKWNS-SSESVRNVTFSADYQILGTDNWKKLPGCQHITSSKC 84
Query 283 SFTVQDLKP-FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF-----WYKI 336
+F+ +LK F + RIR + + S W E + + P I
Sbjct 85 NFSSVELKDVFEKIELRIRAEEGNNT---STWYEVEPFVPFLKAQIGPPDVHLEAEDKAI 141
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA-TKLTVNLTNDR 395
S + ++W L Y V + + S L+ T + + +
Sbjct 142 ILSISPPGTEDSIMW-ALDRSS-----FRYSVVIWKNSSSLEERTETVYPEDKIYKLSPE 195
Query 396 YLATLTVRNLVGKSD-----AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV 450
L V+ + + V I + +++ + ++W P ES
Sbjct 196 ITYCLKVKAELRLQSRVGCYSPVYCINTTERHKVPSPENVQINVDNQAYVLKWDYPYEST 255
Query 451 KKYILEWCVLSDKAPC--ITDWQQED----GTVHRTYLRGNLAESKCYLITVTPVYADGP 504
K P W+Q T ++ Y + V +G
Sbjct 256 TFQAQWLRAFLKKIPGKHSNKWKQIPNCENVTTTHCVFPRDIFSMGIYYVRVRASNGNGT 315
Query 505 GS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG 563
E + + P P + K + + + + Y + Y I
Sbjct 316 SFWSEEKEFNTEVKPIIFPPVISMKSITDDSLHVSVSASEESENMSVNQLYPLVYEVIFW 375
Query 564 NET---AVNVDSSHTEYTLSSLTSDTLYMVRMAAY--TDEGGKDGPEFTFTTPKFAQGEI 618
T V T++T +L T+Y V+ A D K K G
Sbjct 376 ENTSNAERKVLEKRTDFTFPNLKPLTVYCVKARALIENDRWNKGSSYSDTVCEKTKPGNT 435
Query 619 E--AIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF 676
++ +C A ++ + R +K +P+ P S + Q+ P R+
Sbjct 436 SKTWLIAGICTALFSILVVIYVVRVFLRC-VKYVFFPSSKPP--SSVDQYFSDQPLRNLL 492
Query 677 NSKD-----QMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSG 727
S + + N + ++ +E E N+ E+ S + E +SG
Sbjct 493 LSTSEEQTERCFIIENASIITEIE-ETNEVAEVHEEYNSQASQDSGNYSNEDENSG 547
Score = 52.6 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 47/279 (17%), Positives = 83/279 (30%), Gaps = 20/279 (7%)
Query 138 EGKKMRCEWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF----V 192
E K + G E + S + + + T +Y +
Sbjct 137 EDKAIILSISPPGTEDSIMWALDRSSFRYSVVIWKNSSSLEERTETVYPEDKIYKLSPEI 196
Query 193 NIEVWVEAENALGKVT---SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+ V+AE L S + + K P N+ + + L W P
Sbjct 197 TYCLKVKAELRLQSRVGCYSPVYCINTTERHKVPSPENVQI---NVDNQAYVLKWDYPYE 253
Query 250 KSVI----ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
+ + + + K ++ W QIP + +T +D+ Y R+R +
Sbjct 254 STTFQAQWLRAFLKKIPGKHSNKWKQIPNCENVTTTHCVFPRDIFSMGIYYVRVRASNGN 313
Query 306 GKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILD 365
G S WSEE T E +P P + + +V ++ L
Sbjct 314 GT---SFWSEEKEFNT-EVKPIIFPPVISMKSITDDSLHVSVSASEESENMSVNQLYPLV 369
Query 366 YEVTLTRWKSHLQN-YTVNATKLTVNLTNDRYLATLTVR 403
YEV S+ + T T + + R
Sbjct 370 YEVIFWENTSNAERKVLEKRTDFTFPNLKPLTVYCVKAR 408
Score = 51.8 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 37/215 (17%), Positives = 68/215 (32%), Gaps = 11/215 (5%)
Query 137 NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV 196
E + +W + K + +C+ T C V
Sbjct 252 YESTTFQAQWLRAFLKKIPG----KHSNKWKQIPNCENVTTTH--CVFPRDIFSMGIYYV 305
Query 197 WVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
V A N G S+ F+ K PP +S+ + + S + ++ + S +
Sbjct 306 RVRASNGNGTSFWSEEKEFNTEVKPIIFPPV-ISMKSITDDSLHVSVSASEESENMSVNQ 364
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y + Y S + R+ FT +LKP T Y + R + E+ + W+ S
Sbjct 365 LYPLVYEVIFWENTSNAERK-VLEKRTDFTFPNLKPLTVYCVKARALIENDR--WNKGSS 421
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
+ + + +P W V +
Sbjct 422 YSDTVCEKTKPGNTSKTWLIAGICTALFSILVVIY 456
>sp|P16872|IL7RA_MOUSE Interleukin-7 receptor subunit alpha OS=Mus
musculus OX=10090 GN=Il7r PE=1 SV=2
Length=459
Score = 70.7 bits (171), Expect = 2e-11, Method: Composition-based stats.
Identities = 35/143 (24%), Positives = 64/143 (45%), Gaps = 12/143 (8%)
Query 204 LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK--YNIQY 261
LG+ N VK P +L V+ +E + L +T+ P +K + K +++ Y
Sbjct 111 LGQKNLTCKNMAINTIVKAEAPSDLKVVYRKEANDFL-VTFNAPHLKKKYLKKVKHDVAY 169
Query 262 RTKDAST-WSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM--KEDGKGYWSDWSEEAS 318
R + W+ + T R++ + L+P Y ++R + + KG+WS+WS ++
Sbjct 170 RPARGESNWTHVSLFHT---RTTIPQRKLRPKAMYEIKVRSIPHNDYFKGFWSEWSPSST 226
Query 319 GITYEDRPSKAPSFWYKIDPSHT 341
T E + W + PS T
Sbjct 227 FETPEPKNQGG---WDPVLPSVT 246
Score = 59.5 bits (142), Expect = 8e-08, Method: Composition-based stats.
Identities = 45/206 (22%), Positives = 81/206 (39%), Gaps = 17/206 (8%)
Query 556 IFYRTIIGNETAVNVDSSHTEYTLS--SLTSDTLYMVRMA--AYTDEGGKD----GPEFT 607
+ YR G +V HT T+ L +Y +++ + D P T
Sbjct 167 VAYRPARGESNWTHVSLFHTRTTIPQRKLRPKAMYEIKVRSIPHNDYFKGFWSEWSPSST 226
Query 608 FTTPKFA-QGEIEAIVVPVCLAFLLTTLLGVLFC--FNKRDLIKKHIWPNVPDPSKSHIA 664
F TP+ QG + ++ V + L + L V+ K+ IK +WP++PD K +
Sbjct 227 FETPEPKNQGGWDPVLPSVTILSLFSVFLLVILAHVLWKK-RIKPVVWPSLPD-HKKTLE 284
Query 665 QWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGH 724
Q N + + + D +V VE + P DL + + E++ T+GH
Sbjct 285 QLCKKPKTSLNVSFNPESFLDCQIHEVKGVEARDEVESFLPNDLPA----QPEELETQGH 340
Query 725 SSGIGGSSCMSSSRPSISSSDENESS 750
+ + ++ + S + ES
Sbjct 341 RAAVHSANRSPETSVSPPETVRRESP 366
>sp|P08069|IGF1R_HUMAN Insulin-like growth factor 1 receptor OS=Homo
sapiens OX=9606 GN=IGF1R PE=1 SV=1
Length=1367
Score = 71.8 bits (174), Expect = 3e-11, Method: Composition-based stats.
Identities = 33/182 (18%), Positives = 65/182 (36%), Gaps = 17/182 (9%)
Query 476 TVHRTYLRGNLAESKCYLITVTPVYAD----GPGSPESIKAYL--KQAPPSKGPTVRTKK 529
RT + NL Y I + + G + + A + V +
Sbjct 784 NKERTVI-SNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEP 842
Query 530 VGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY---TLSSLTSDT 586
+N L+W + + NG I Y I Y + + ++ + +Y L+ L
Sbjct 843 RPENSIFLKWPE--PENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPG- 899
Query 587 LYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE----IEAIVVPVCLAFLLTTLLGVLFCFN 642
Y R+ A + G + F + G I +PV + ++ L+ +L+ F+
Sbjct 900 NYTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFH 959
Query 643 KR 644
++
Sbjct 960 RK 961
Score = 61.4 bits (147), Expect = 4e-08, Method: Composition-based stats.
Identities = 26/170 (15%), Positives = 56/170 (33%), Gaps = 37/170 (22%)
Query 228 LSVINSEELSSILKLTW---TNPSIKSVIILKYNIQYRTK--------------DASTWS 270
L ++ + + +TW P + ++ + + Y+ +++W+
Sbjct 493 LHFTSTTTSKNRIIITWHRYRPPDYRD--LISFTVYYKEAPFKNVTEYDGQDACGSNSWN 550
Query 271 QIPPEDTAST--RSSFTVQDLKPFTEYVFRIRCM------KEDGKGYWSDWSEEASGITY 322
+ + + + LKP+T+Y ++ + + +G SE T
Sbjct 551 MVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGA---KSEILYIRTN 607
Query 323 EDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR 372
PS S + + + W PP NG + Y V R
Sbjct 608 ASVPSIPLDVL-----SASNSSSQLIVKWN--PPSLPNGNLSYYIVRWQR 650
Score = 53.7 bits (127), Expect = 8e-06, Method: Composition-based stats.
Identities = 20/160 (13%), Positives = 42/160 (26%), Gaps = 28/160 (18%)
Query 431 KAFPKDNMLWVEWT----TPRESVKKYILEWCV---------LSDKAPCITDWQQED--- 474
N + + W + + + + A W D
Sbjct 497 STTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDL 556
Query 475 ---GTVHRTYLRGNLAESKCYLITVTPVYAD-------GPGSPESIKAYLKQAPPSKGPT 524
V L L Y + V V E + + PS
Sbjct 557 PPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLD 616
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN 564
V + ++ +++W+ P + NG + Y + ++ +
Sbjct 617 VLSASNSSSQLIVKWN--PPSLPNGNLSYYIVRWQRQPQD 654
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 30/175 (17%), Positives = 52/175 (30%), Gaps = 15/175 (9%)
Query 147 DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN---- 202
R T + + R TV + F + + + N
Sbjct 752 SRSRNTTAADTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAE 811
Query 203 ALGKVTSDHINFDPV----YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
LG S+ + + P P V + + L W P + +IL Y
Sbjct 812 KLGCSASNFVFARTMPAEGADDIPGP-----VTWEPRPENSIFLKWPEPENPNGLILMYE 866
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
I+Y ++ + ++ + L P Y RI+ G G W+D
Sbjct 867 IKYGSQVEDQRECVSRQE-YRKYGGAKLNRLNPG-NYTARIQATSLSGNGSWTDP 919
Score = 50.6 bits (119), Expect = 7e-05, Method: Composition-based stats.
Identities = 26/155 (17%), Positives = 43/155 (28%), Gaps = 13/155 (8%)
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWY 334
E + + +L+PFT Y I + + S T P++
Sbjct 779 ESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTM---PAEGADDIP 835
Query 335 KIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL-------TRWKSHLQNYTVNATKL 387
+ ++ L W P NG IL YE+ S + KL
Sbjct 836 GPVTWEPRPENSIFLKW--PEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKL 893
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
+ Y A + +L G +
Sbjct 894 NRLNPGN-YTARIQATSLSGNGSWTDPVFFYVQAK 927
Score = 40.6 bits (93), Expect = 0.082, Method: Composition-based stats.
Identities = 18/77 (23%), Positives = 34/77 (44%), Gaps = 6/77 (8%)
Query 191 FVNIEVWVEAENALGKVTSDHIN-----FDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ V+V+A L V +DHI + P L V+++ SS L + W
Sbjct 574 WTQYAVYVKAVT-LTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWN 632
Query 246 NPSIKSVIILKYNIQYR 262
PS+ + + Y ++++
Sbjct 633 PPSLPNGNLSYYIVRWQ 649
>sp|P26896|IL2RB_RAT Interleukin-2 receptor subunit beta OS=Rattus
norvegicus OX=10116 GN=Il2rb PE=2 SV=1
Length=537
Score = 70.7 bits (171), Expect = 3e-11, Method: Composition-based stats.
Identities = 38/211 (18%), Positives = 70/211 (33%), Gaps = 19/211 (9%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWATHKFADC---KAKRDTPTSC--- 182
+L C N + C W E L T+ + ++ + R +C
Sbjct 32 SHLKCFYNSRANVSCMWSP--EEALNVTSCHIHAKSDMRHWNKTCELTPVRQASWACNLI 89
Query 183 ----TVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
S + + V G F P ++ PH+L V++ E +
Sbjct 90 LGPLPDSQSLTSVDLLSLSVVCWEEKGWRRVKTCTFHPFDNLRLIAPHSLQVLHIE--TR 147
Query 239 ILKLTWTNPSIKSV--IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
++W + L++ + R D +W + ++ L P T Y
Sbjct 148 RCNISWEVSQVSHYVNPYLEFEARRRLLD-RSWEDASVFSLKQRQQWIFLETLTPDTSYE 206
Query 297 FRIRCMKEDGK-GYWSDWSEEASGITYEDRP 326
++R + + GK WS WS+ + T P
Sbjct 207 LQVRVIAQRGKTRTWSPWSQPMAFRTRPADP 237
Score = 48.3 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 44/232 (19%), Positives = 82/232 (35%), Gaps = 25/232 (11%)
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS--SHTEYT 578
+++ + + W+ V + R + + +V S ++
Sbjct 135 APHSLQVLHIETRRCNISWEVSQVSHYVNPYLEFEARRRLLDRSWEDASVFSLKQRQQWI 194
Query 579 -LSSLTSDTLYMVRMAAYTDEGGKD--GPEFT---FTTPKFAQGEIE-------AIVVPV 625
L +LT DT Y +++ G P F T EI ++V
Sbjct 195 FLETLTPDTSYELQVRVIAQRGKTRTWSPWSQPMAFRTRPADPKEIFPLPWLRCLLLVLG 254
Query 626 CLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYS- 684
C L+ + ++ C +K + ++PDPS+ S H + S S
Sbjct 255 CFFGFLSCVCVLVKCRYLGPWLKTLLKCHIPDPSEFFSQLSSQHGGDLQKWLSSPVPQSF 314
Query 685 ---DGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSC 733
G+ ++S +E+ D K + LF+KEK ++ SG +SC
Sbjct 315 FSPTGSAPEISPLEVLDRDSK-----TMQMLLFQKEKASSP-SPSGHSQASC 360
>sp|D3ZB51|TUTLB_RAT Protein turtle homolog B OS=Rattus norvegicus
OX=10116 GN=Igsf9b PE=1 SV=1
Length=1328
Score = 71.0 bits (172), Expect = 4e-11, Method: Composition-based stats.
Identities = 37/226 (16%), Positives = 72/226 (32%), Gaps = 18/226 (8%)
Query 122 SGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL---KSEWATHKFADCKAKRDT 178
G P P ++ + W+ G + E F++ ++++ H +
Sbjct 506 IGTSPHAPGSVR-VHVSMTTANVSWEPGYDGGYEQTFSVWMKRAQFGPHDWLSLSVPLGP 564
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
+ V A+N LG + P L ++ +
Sbjct 565 SWLLVDSLEPE--TAYQFSVLAQNRLGTSAFSEVVTVNTLAFPVTTPEPLVLVTPPRCLT 622
Query 239 I------LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
+ L+W P+ S I +Y +++R W + + T F +DL
Sbjct 623 ANRTQQGVLLSWLPPANHSFPIDRYIMEFRV--GERWEMLD-DAIPGTDGEFFAKDLSQD 679
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
T Y FR+ + +D S+ S A + + P + P
Sbjct 680 TWYEFRVLAVMQDLI---SEPSNIAGVSSTDIFPQPDLTDDGLARP 722
Score = 61.8 bits (148), Expect = 3e-08, Method: Composition-based stats.
Identities = 38/248 (15%), Positives = 69/248 (28%), Gaps = 33/248 (13%)
Query 200 AENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A N + +T S H+ P+ P ++ V + ++W ++
Sbjct 490 ATNVVTSITASTHLTVIGTS---PHAPGSVRV---HVSMTTANVSWEPGYDG-GYEQTFS 542
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+ + + V L+P T Y F + G S +SE +
Sbjct 543 VWMKRAQFGPHDWLSLSVPLGPS-WLLVDSLEPETAYQFSVLAQNRLGT---SAFSEVVT 598
Query 319 GITYEDRPSKAPSFWYKIDP----SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--- 371
T P P + P + + + V L W LPP + I Y +
Sbjct 599 VNTL-AFPVTTPEPLVLVTPPRCLTANRTQQGVLLSW--LPPANHSFPIDRYIMEFRVGE 655
Query 372 RWKSHLQNYTVNATKLTVNLTNDR--YLATLTVR---------NLVGKSDAAVLTIPACD 420
RW+ + + Y + N+ G S + P
Sbjct 656 RWEMLDDAIPGTDGEFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSSTDIFPQPDLT 715
Query 421 FQATHPVM 428
+
Sbjct 716 DDGLARPV 723
Score = 57.6 bits (137), Expect = 5e-07, Method: Composition-based stats.
Identities = 85/658 (13%), Positives = 164/658 (25%), Gaps = 105/658 (16%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P+ + + T C F + W + ++ + +VT
Sbjct 146 PQYIEAKEGGSITMTCT-------AFGNPKPIVTWLKEGTLLSASGKYQVSDGSLTVTSV 198
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLPP---EKPKNLSCIVNEGKKMRCEWDGG 149
TC + + V+ ++ PP P+N++ +++ + C
Sbjct 199 S-REDRGAYTCRAYSIQ--GEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTC----- 250
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIE----VWVEAENALG 205
R N T W + ++ V E N+LG
Sbjct 251 RAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDAGKYTCVPSNSLG 310
Query 206 KVTSDHINFDPVY--KVKPNPPH---NLSVI-----NSEELSSILKLTWTNPSIKSVIIL 255
+ S Y +V PP + + + + W
Sbjct 311 RSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRP----- 365
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
+ + W+ + ED + T + L +T C+ + G +
Sbjct 366 -----LQVEKNLGWTLM--EDGSIRIEEATEEALGTYT-------CVPYNTLGTMGQSAP 411
Query 316 EASGITYEDRPSKAPSFWYK-------IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
+ + P + Y+ + P G + W+ +
Sbjct 412 ARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRKVGKPS---------- 461
Query 369 TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+S + + D N+V + T + H
Sbjct 462 -----RSKHNALPSGSLQFRALSKEDHGEWECVATNVV--TSITASTHLTVIGTSPHAPG 514
Query 429 DLKAFPKDNMLWVEWTTPRESVKKYIL---EWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
++ V W + Y W + P L +
Sbjct 515 SVRVHVSMTTANVSWEPGYD--GGYEQTFSVWMKRAQFGPHDWLSLSVPLGPSW-LLVDS 571
Query 486 LAESKCYLITVTPVYADGPGSPESIK--------AYLKQAPPSK-GPTVRTKKVGKNEAV 536
L Y +V G + + + P T + +
Sbjct 572 LEPETAYQFSVLAQNRLGTSAFSEVVTVNTLAFPVTTPEPLVLVTPPRCLTANRTQQGVL 631
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTIIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
L W LP + I Y + +R E + + E+ L+ DT Y R+ A
Sbjct 632 LSW--LPPANHSFPIDRYIMEFRVGERWEMLDDAIPGTDGEFFAKDLSQDTWYEFRVLAV 689
Query 596 ---------TDEGGKDG---PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCF 641
G P+ T A+ + IV +C + CF
Sbjct 690 MQDLISEPSNIAGVSSTDIFPQPDLTDDGLARPVLAGIVATICFLAAAILFSTLAACF 747
>sp|Q05BQ1|TUTLA_MOUSE Protein turtle homolog A OS=Mus musculus
OX=10090 GN=Igsf9 PE=1 SV=2
Length=1179
Score = 70.7 bits (171), Expect = 5e-11, Method: Composition-based stats.
Identities = 53/315 (17%), Positives = 85/315 (27%), Gaps = 46/315 (15%)
Query 40 LHSNFTAVCVLKEKCMDYFHVNANYIVW-KTNHFTIPKEQYTIINRTASSVTFTDIASLN 98
+ C + + W K + Q N +
Sbjct 432 VGRELLIPCSAR-------GDPPPIVSWAKVGRGLQGQAQVDSNNSLVLRPLTKEAQGRW 484
Query 99 IQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNF 158
N + NVY G P N+S +V K W+ G + F
Sbjct 485 ECSASNAVARVTTSTNVYV----LGTSPHVVTNVS-VVPLPKGANVSWEPGFDGGYLQRF 539
Query 159 TLKSEWATHKFADCKAKRDTPTSCTVDYSTVY------FVNIEVWVEAENALGKVTSDHI 212
++ K D + + + + + V A+N LG I
Sbjct 540 SVWY-TPLAKRPDRAHHDWVSLAVPIGATHLLVPGLQAHAQYQFSVLAQNKLGSGPFSEI 598
Query 213 NFD---------------PVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSVIILK 256
P P PP L + + L W P + +
Sbjct 599 VLSIPEGLPTTPAAPGLPPTEIPPPLSPPRGLVAV---RTPRGVLLHWDPPELIPGRLDG 655
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y ++ R + + W + + A T V L Y FR+ + Y SD S
Sbjct 656 YILEGR-QGSQGWEILD-QGVAGTEIQLLVPGLIKDVLYEFRLVAFADS---YVSDPSNV 710
Query 317 ASGIT--YEDRPSKA 329
A+ T E PS+
Sbjct 711 ANISTSGLEVYPSRT 725
Score = 65.3 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 39/243 (16%), Positives = 71/243 (29%), Gaps = 24/243 (10%)
Query 421 FQATHPVMDLKAFPKDNMLWVEWTT--PRESVKKYILEWCVLS-DKAPCITDWQQEDGTV 477
+ H V ++ P V W ++++ + + L+ DW +
Sbjct 505 GTSPHVVTNVSVVPLPKGANVSWEPGFDGGYLQRFSVWYTPLAKRPDRAHHDWVSLAVPI 564
Query 478 HRTYLRG-NLAESKCYLITVTPVYADGPGSPESIKAYLKQA----------------PPS 520
T+L L Y +V G G I + + PP
Sbjct 565 GATHLLVPGLQAHAQYQFSVLAQNKLGSGPFSEIVLSIPEGLPTTPAAPGLPPTEIPPPL 624
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN--VDSSHTEYT 578
P +L WD P ++ G + Y + R ++ V + +
Sbjct 625 SPPRGLVAVRTPRGVLLHWD--PPELIPGRLDGYILEGRQGSQGWEILDQGVAGTEIQLL 682
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
+ L D LY R+ A+ D D + + +P L + +
Sbjct 683 VPGLIKDVLYEFRLVAFADSYVSDPSNVANISTSGLEVYPSRTQLPGLLPQPVLAGVVGG 742
Query 639 FCF 641
CF
Sbjct 743 VCF 745
Score = 56.4 bits (134), Expect = 1e-06, Method: Composition-based stats.
Identities = 35/242 (14%), Positives = 63/242 (26%), Gaps = 42/242 (17%)
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ G+ S + A T + S + S + + W+ P G
Sbjct 478 KEAQGRWECSASNAVARVTTSTNVYVLGTSPHVVTNVSVVPLPKGANVSWE---PGFDGG 534
Query 362 KILDYEVTLTR-----------WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD 410
+ + V T W S + + +Y ++ +N +G
Sbjct 535 YLQRFSVWYTPLAKRPDRAHHDWVSLAVPIGATHLLVPGLQAHAQYQFSVLAQNKLGSGP 594
Query 411 AAVLTI----------------PACDFQATHPVMDLKAFPKDNMLWVEWTTP---RESVK 451
+ + + P P L A + + W P +
Sbjct 595 FSEIVLSIPEGLPTTPAAPGLPPTEIPPPLSPPRGLVAVRTPRGVLLHWDPPELIPGRLD 654
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRT---YLRGNLAESKCYLITVTPVYADGPGSPE 508
YILE S W+ D V T L L + Y + P
Sbjct 655 GYILEGRQGSQG------WEILDQGVAGTEIQLLVPGLIKDVLYEFRLVAFADSYVSDPS 708
Query 509 SI 510
++
Sbjct 709 NV 710
Score = 53.7 bits (127), Expect = 8e-06, Method: Composition-based stats.
Identities = 57/457 (12%), Positives = 119/457 (26%), Gaps = 74/457 (16%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS---------EELSSILKLTWTNPSI 249
+A ++ G +T V PP N +V +S E + L +W +
Sbjct 207 QASSSEGSITHATQLLVLGPPVIVVPPSNSTVNSSQDVSLACRAEAYPANLTYSWFQDGV 266
Query 250 KSVIILKYNIQYR-TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
I + + R D S W Q D A + C+ +G
Sbjct 267 NVFHISRLQSRVRILVDGSLWLQATQPDDAGHYT------------------CVPSNGFL 308
Query 309 YWSDWSEEASGI-----TYEDRPSKAPSFWYKIDPSHTQGYRTVQ-LVWKTLPPFEANGK 362
+ S + + T + P+ + + + + W K
Sbjct 309 HPPSASAYLTVLYPAQVTVMPPETPLPTGMRGVIRCPVRANPPLLFVTWTKDGQALQLDK 368
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
+ + + N + T N +G + + +T
Sbjct 369 FPG-----------WSLGPEGSLIIALGNENALGEYSCTPYNSLGTAGPSPVTQVLLKAP 417
Query 423 AT----HPVMDLKAFPKDNML--WVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
+ ++ ++ P I+ W + +
Sbjct 418 PAFIDQPKEEYFQEVGRELLIPCSARGDPPP------IVSWAKVGRGLQGQAQVDSNNSL 471
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAV 536
V R + +C S Y+ P V + K A
Sbjct 472 VLRPLTKEAQGRWEC------SASNAVARVTTSTNVYVLGTSPHVVTNVSVVPLPKG-AN 524
Query 537 LEWDQLPVDVQNGFIRNYTIFYRTII-------GNETAVNVDSSHTEYTLSSLTSDTLYM 589
+ W+ G+++ ++++Y + + ++ V T + L + Y
Sbjct 525 VSWE---PGFDGGYLQRFSVWYTPLAKRPDRAHHDWVSLAVPIGATHLLVPGLQAHAQYQ 581
Query 590 VRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVC 626
+ A G E + P+ A +P
Sbjct 582 FSVLAQNKLGSGPFSEIVLSIPEGLPTTPAAPGLPPT 618
>sp|E9PZ19|TUTLB_MOUSE Protein turtle homolog B OS=Mus musculus
OX=10090 GN=Igsf9b PE=1 SV=1
Length=1328
Score = 70.7 bits (171), Expect = 5e-11, Method: Composition-based stats.
Identities = 37/226 (16%), Positives = 72/226 (32%), Gaps = 18/226 (8%)
Query 122 SGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL---KSEWATHKFADCKAKRDT 178
G P P ++ + W+ G + E F++ ++++ H +
Sbjct 506 IGTSPHAPGSVR-VHVSMTTANVSWEPGYDGGYEQTFSVWMKRAQFGPHDWLSLSVPPGP 564
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSS 238
+ V A+N LG + P L ++ +
Sbjct 565 SWLLVDSLEPE--TAYQFSVLAQNRLGTSAFSEVVTVNTLAFPVTTPEPLVLVTPPRCLT 622
Query 239 I------LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
+ L+W P+ S I +Y +++R W + + T F +DL
Sbjct 623 ANRTQQGVLLSWLPPANHSFPIDRYIMEFRV--GERWEMLD-DAIPGTDGDFFAKDLSQD 679
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
T Y FR+ + +D S+ S A + + P + P
Sbjct 680 TWYEFRVLAVMQDLI---SEPSNIAGVSSTDIFPQPDLTDDGLARP 722
Score = 61.4 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 38/248 (15%), Positives = 68/248 (27%), Gaps = 33/248 (13%)
Query 200 AENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A N + +T S H+ P+ P ++ V + ++W ++
Sbjct 490 ATNVVTSITASTHLTVIGTS---PHAPGSVRV---HVSMTTANVSWEPGYDG-GYEQTFS 542
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEAS 318
+ + + V L+P T Y F + G S +SE +
Sbjct 543 VWMKRAQFGPHDWLSLSVPPGPS-WLLVDSLEPETAYQFSVLAQNRLGT---SAFSEVVT 598
Query 319 GITYEDRPSKAPSFWYKIDP----SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--- 371
T P P + P + + + V L W LPP + I Y +
Sbjct 599 VNTL-AFPVTTPEPLVLVTPPRCLTANRTQQGVLLSW--LPPANHSFPIDRYIMEFRVGE 655
Query 372 RWKSHLQNYTVNATKLTVNLTNDR--YLATLTVR---------NLVGKSDAAVLTIPACD 420
RW+ + Y + N+ G S + P
Sbjct 656 RWEMLDDAIPGTDGDFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSSTDIFPQPDLT 715
Query 421 FQATHPVM 428
+
Sbjct 716 DDGLARPV 723
Score = 57.6 bits (137), Expect = 5e-07, Method: Composition-based stats.
Identities = 39/266 (15%), Positives = 67/266 (25%), Gaps = 32/266 (12%)
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL---EW 457
N+V + T + H ++ V W + Y W
Sbjct 489 VATNVV--TSITASTHLTVIGTSPHAPGSVRVHVSMTTANVSWEPGYD--GGYEQTFSVW 544
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK------ 511
+ P L +L Y +V G + +
Sbjct 545 MKRAQFGPHDWLSLSVPPGPSW-LLVDSLEPETAYQFSVLAQNRLGTSAFSEVVTVNTLA 603
Query 512 --AYLKQAPPSK-GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET-A 567
+ P T + +L W LP + I Y + +R E
Sbjct 604 FPVTTPEPLVLVTPPRCLTANRTQQGVLLSW--LPPANHSFPIDRYIMEFRVGERWEMLD 661
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAY---------TDEGGKDG---PEFTFTTPKFAQ 615
+ + ++ L+ DT Y R+ A G P+ T A+
Sbjct 662 DAIPGTDGDFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSSTDIFPQPDLTDDGLAR 721
Query 616 GEIEAIVVPVCLAFLLTTLLGVLFCF 641
+ IV +C + CF
Sbjct 722 PVLAGIVATICFLAAAILFSTLAACF 747
Score = 47.9 bits (112), Expect = 5e-04, Method: Composition-based stats.
Identities = 40/255 (16%), Positives = 75/255 (29%), Gaps = 46/255 (18%)
Query 298 RIRCMKEDGKGYW----SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
+ R + ++ G W ++ + T+ +P + T + W+
Sbjct 474 QFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVH--VSMTTANVSWEP 531
Query 354 LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNL-----------TNDRYLATLTV 402
G YE T + W Q + L+V Y ++
Sbjct 532 -------GYDGGYEQTFSVWMKRAQFGPHDWLSLSVPPGPSWLLVDSLEPETAYQFSVLA 584
Query 403 RNLVGKSDAA------VLTIPACDFQA---THPVMDLKAFPKDNMLWVEWTTPRE---SV 450
+N +G S + L P + P L A + + W P +
Sbjct 585 QNRLGTSAFSEVVTVNTLAFPVTTPEPLVLVTPPRCLTANRTQQGVLLSWLPPANHSFPI 644
Query 451 KKYILEWCVLSDKAPCITDWQQEDGTVHRT---YLRGNLAESKCYLITVTPVYADGPGSP 507
+YI+E+ V W+ D + T + +L++ Y V V D P
Sbjct 645 DRYIMEFRVGER-------WEMLDDAIPGTDGDFFAKDLSQDTWYEFRVLAVMQDLISEP 697
Query 508 ESIKAYLKQAPPSKG 522
+I +
Sbjct 698 SNIAGVSSTDIFPQP 712
>sp|Q70E20|SNED1_MOUSE Sushi, nidogen and EGF-like domain-containing
protein 1 OS=Mus musculus OX=10090 GN=Sned1 PE=2 SV=2
Length=1403
Score = 70.7 bits (171), Expect = 5e-11, Method: Composition-based stats.
Identities = 42/296 (14%), Positives = 81/296 (27%), Gaps = 38/296 (13%)
Query 321 TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY 380
T E P A V + W A + Y VT +
Sbjct 903 TKELLPPTALRVERV-------EESGVSISWSPPEGTTARQVLDGYAVTYASSDGSSRRT 955
Query 381 -----TVNATKLTVNLTNDRYLATL--TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF 433
+ ++ +L Y ++ RN K+D + +
Sbjct 956 DFVDRSRSSHQLRALAAGRAYNISVFSVKRNTNNKNDISRPAALLTRTRPRPIEDFEVTN 1015
Query 434 PKDNMLWVEW-----TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
N + V+W S + + + + D +V R G+L
Sbjct 1016 ISANAISVQWALHRIQHATVSRVRVSILY-----PEASAVQSTEVDRSVDR-LTFGDLLP 1069
Query 489 SKCYLITVTPVYADGPG-------SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
+ Y + +T + G + + + + PP+ + +V A + WD
Sbjct 1070 GRRYTVRLTTLSGPGGAEYPTESLASAPLNVWTRPLPPA---NLTASRVTATSAHMIWDT 1126
Query 542 LPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTD 597
+ Y I T ++ + YT+ L Y + + A
Sbjct 1127 PAP---GISLEAYVINVTTSQSTKSRYIPNGKLVSYTVRDLMPGRRYQLSVTAVQS 1179
Score = 69.1 bits (167), Expect = 2e-10, Method: Composition-based stats.
Identities = 60/339 (18%), Positives = 111/339 (33%), Gaps = 31/339 (9%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKS--VIILKYNIQYRTKDASTWSQIPPEDTAST 280
PP L V EE + ++W+ P + ++ Y + Y + D S+ + +
Sbjct 907 LPPTALRVERVEESG--VSISWSPPEGTTARQVLDGYAVTYASSDGSSRRT---DFVDRS 961
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
RSS ++ L Y + +K + +D S A+ +T RP F
Sbjct 962 RSSHQLRALAAGRAYNISVFSVKRNTNNK-NDISRPAALLT-RTRPRPIEDFEV-----T 1014
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTL-----TRWKSHLQNYTVNATKLTVNLTNDR 395
+ + W A + V++ + +S + +V+ L R
Sbjct 1015 NISANAISVQWALHRIQHA--TVSRVRVSILYPEASAVQSTEVDRSVDRLTFGDLLPGRR 1072
Query 396 YLATLTVRNLVGKSDAAVLTIPACDF----QATHPVMDLKAFPKDNMLWVEWTTPRESVK 451
Y LT + G ++ ++ + + P + + W TP
Sbjct 1073 YTVRLTTLSGPGGAEYPTESLASAPLNVWTRPLPPANLTASRVTATSAHMIWDTPA---P 1129
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPV--YADGPGSPES 509
LE V++ T + +Y +L + Y ++VT V G E
Sbjct 1130 GISLEAYVINVTTSQSTKSRYIPNGKLVSYTVRDLMPGRRYQLSVTAVQSTEQGQLHSEP 1189
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
Y+ P G R G + +L PV +
Sbjct 1190 AHLYII-TSPRDGTDRRWHHGGHHSRMLRNRPAPVRLPE 1227
Score = 68.0 bits (164), Expect = 4e-10, Method: Composition-based stats.
Identities = 74/441 (17%), Positives = 144/441 (33%), Gaps = 58/441 (13%)
Query 417 PACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYIL-EWCVLSDKAPCITDWQQEDG 475
C + P +++ + + W+ P + + +L + V + +
Sbjct 900 KDCTKELLPPTALRVERVEESGVSISWSPPEGTTARQVLDGYAVTYASSDGSSRRTDFVD 959
Query 476 TVHRTYLRGNLAESKCYLITV----TPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
++ LA + Y I+V S + A L + P +
Sbjct 960 RSRSSHQLRALAAGRAYNISVFSVKRNTNNKNDISRPA--ALLTRTRPRPIEDFEVTNIS 1017
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
N ++W + +I Y + VD S T L Y VR
Sbjct 1018 ANAISVQWALHRIQHATVSRVRVSILYPEA-SAVQSTEVDRSVDRLTFGDLLPGRRYTVR 1076
Query 592 MAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHI 651
+ + GG + P T A + P+ A L + + I
Sbjct 1077 LTTLSGPGGAEYP-----TESLASAPLNVWTRPLPPANLTASRVTATS--------AHMI 1123
Query 652 WPNVPDP-------------SKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEA 698
W + P P S+S +++ P+ ++ +D M G +SV +++
Sbjct 1124 W-DTPAPGISLEAYVINVTTSQSTKSRYIPN-GKLVSYTVRDLMP--GRRYQLSVTAVQS 1179
Query 699 NDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSR------PSISSSDENESSQN 752
++ + L + + T+ G S M +R P + +++ + +
Sbjct 1180 TEQGQLHSEPAHLYIITSPRDGTDRRWHHGGHHSRMLRNRPAPVRLPELRLLNDHSAPET 1239
Query 753 TSSTVQYSTVVH-----SGYRHQVPSVQVFSRSESTQPL-LDSEERPEDLQLVDHVDGGD 806
+ + ++S +V S +PS V RS+ T P+ L + E PE + L
Sbjct 1240 PTQSSRFSELVDGRGRVSARFGGLPSRAVTVRSQPTTPVPLKNTEAPEQVHLALQ----- 1294
Query 807 GILPRQQYFKQNCSQHESSPD 827
LP+ K S S +
Sbjct 1295 --LPKNSS-KDTESTPGSCSE 1312
Score = 44.8 bits (104), Expect = 0.004, Method: Composition-based stats.
Identities = 23/126 (18%), Positives = 43/126 (34%), Gaps = 12/126 (10%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
AE + S +N +P PP NL+ ++ + W P+ +
Sbjct 1086 AEYPTESLASAPLNVWT----RPLPPANLTASRV--TATSAHMIWDTPAPGISLE----- 1134
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW-SDWSEEAS 318
Y ++ S S+TV+DL P Y + ++ +G S+ +
Sbjct 1135 AYVINVTTSQSTKSRYIPNGKLVSYTVRDLMPGRRYQLSVTAVQSTEQGQLHSEPAHLYI 1194
Query 319 GITYED 324
+ D
Sbjct 1195 ITSPRD 1200
>sp|Q80U40|RIMB2_MOUSE RIMS-binding protein 2 OS=Mus musculus
OX=10090 GN=Rimbp2 PE=1 SV=3
Length=1072
Score = 70.7 bits (171), Expect = 6e-11, Method: Composition-based stats.
Identities = 42/313 (13%), Positives = 97/313 (31%), Gaps = 36/313 (12%)
Query 129 PKNLSCIVNEGKKMRCEWDGGRET---HLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P+ ++ I K + W+ +++ + + T + ++
Sbjct 314 PRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMSLALGRRTKAL----IE 369
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ V+ + G V P L V N ++S+ +L+W
Sbjct 370 KLNTAACTYRISVQCVTSRGNSDELQCTLLVGKDVVV-APSQLRVDNITQISA--QLSW- 425
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P+ + + + ++ + + R + +L+P Y ++
Sbjct 426 LPTNSNYSHIIFL-----------NEEELDIVKAARYKYQFFNLRPNMAYKVKVLAQPHQ 474
Query 306 GKGYWSDWSEEASG----ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL---PPFE 358
W E+ + + P+ P+ + +VQ+ WK P
Sbjct 475 M--PWQLPLEQREKKEACVEFSTLPAGPPAPPQDVTVHAGATAASVQVSWKPPALTPTGL 532
Query 359 ANG-KILDYEVTL---TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS-DAAV 413
+NG + Y V + A +L + + ++ ++ G+S D+A+
Sbjct 533 SNGANVTGYGVYAKGQRVAEVIAPTADGTAVELIRLRSLEAKAVSVRTLSVQGESMDSAL 592
Query 414 LTIPACDFQATHP 426
IP P
Sbjct 593 AAIPPDLLVPPAP 605
Score = 63.3 bits (152), Expect = 9e-09, Method: Composition-based stats.
Identities = 43/275 (16%), Positives = 76/275 (28%), Gaps = 28/275 (10%)
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLT 401
Q ++V + W+ G + Y V + + L L ++
Sbjct 322 QLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMSLALGRRTKALIEKLNTAACTYRIS 381
Query 402 V--RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
V G SD T+ P + W P S +I+
Sbjct 382 VQCVTSRGNSDELQCTLLVGKDVVVAPSQLRVDNITQISAQLSW-LPTNSNYSHII---F 437
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA-- 517
L+++ I + Y NL + Y + V P + K+A
Sbjct 438 LNEEELDIVKAAR------YKYQFFNLRPNMAYKVKVLAQPHQMPWQLPLEQREKKEACV 491
Query 518 --------PPSKGPTVRTKK-VGKNEAVLEWDQL---PVDVQNG-FIRNYTIFYRTIIGN 564
PP+ V + W P + NG + Y ++ +
Sbjct 492 EFSTLPAGPPAPPQDVTVHAGATAASVQVSWKPPALTPTGLSNGANVTGYGVYAKGQRVA 551
Query 565 ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
E + + T L L S V + + +G
Sbjct 552 EV-IAPTADGTAVELIRLRSLEAKAVSVRTLSVQG 585
Score = 50.6 bits (119), Expect = 7e-05, Method: Composition-based stats.
Identities = 42/342 (12%), Positives = 91/342 (27%), Gaps = 47/342 (14%)
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS--VIILKYNIQYRTKDASTW 269
++ + + P+ + ++L+ + + W P++ + YN+
Sbjct 299 LDVNIDDIGEDTVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNV-------LVD 351
Query 270 SQIPPEDTASTRSSFTVQDLK-PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP-S 327
+ R+ ++ L Y ++C+ G S+E +
Sbjct 352 KETRMSLALGRRTKALIEKLNTAACTYRISVQCVTSRGN------SDELQCTLLVGKDVV 405
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKL 387
APS + + + QL W LP I + L + + +
Sbjct 406 VAPSQLRVDNITQI----SAQLSW--LPTNSNYSHI----IFLNEEELDIVKAARYKYQF 455
Query 388 TVNLTNDRYLATLTVRN---------LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDN- 437
N Y + + + A + P D+
Sbjct 456 FNLRPNMAYKVKVLAQPHQMPWQLPLEQREKKEACVEFSTLPAGPPAPPQDVTVHAGATA 515
Query 438 -MLWVEWTTPRESVKKY-----ILEWCVLSDKAPCITDWQQEDGTVHRTYLR-GNLAESK 490
+ V W P + + + V + + T T + L +
Sbjct 516 ASVQVSWKPPALTPTGLSNGANVTGYGVYAKGQRVA---EVIAPTADGTAVELIRLRSLE 572
Query 491 CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGK 532
++V + G ++ A P RT K
Sbjct 573 AKAVSVRTLSVQGESMDSALAAIPPDLLVPPAPHPRTAPPPK 614
Score = 40.6 bits (93), Expect = 0.090, Method: Composition-based stats.
Identities = 15/108 (14%), Positives = 39/108 (36%), Gaps = 6/108 (6%)
Query 497 TPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
+ + +G G+ + + + + K ++ W+ V G + +Y +
Sbjct 289 SGITDNGGGTLDVNIDDIGEDTVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNV 348
Query 557 FYRTIIGNETAVNVD-SSHTEYTLSSLTSDT-LYMVRMAAYTDEGGKD 602
++ ET +++ T+ + L + Y + + T G D
Sbjct 349 ----LVDKETRMSLALGRRTKALIEKLNTAACTYRISVQCVTSRGNSD 392
>sp|Q70KF4|CMYA5_MOUSE Cardiomyopathy-associated protein 5 OS=Mus
musculus OX=10090 GN=Cmya5 PE=1 SV=2
Length=3739
Score = 70.7 bits (171), Expect = 6e-11, Method: Composition-based stats.
Identities = 37/260 (14%), Positives = 75/260 (29%), Gaps = 16/260 (6%)
Query 404 NLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDK 463
+ +SD + + P + + V W+ +E V +CV +
Sbjct 3360 DSSARSDQMLKQVAVPQPPRLEPQE--PSSATSTTIAVYWSVNKEDVVDSFQVYCVEEPQ 3417
Query 464 APCITDWQQEDGTVH---RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS 520
+ E+ + + +L +CY + V V G P + + PS
Sbjct 3418 DDQEINELVEEYRLTVKESCCIFEDLEPDRCYQVWVMAVNFTGCSLPSERAIF--RTAPS 3475
Query 521 KGPTVRTKKVG--KNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDSSHTEY 577
P + + N A + W + YT+ Y R + S +
Sbjct 3476 T-PVIHVEDCTVCWNTATVRWRPANPEATE----TYTLEYCRQHSPEGEGLRSFSGIKGH 3530
Query 578 TLS-SLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLG 636
L +L + Y + A G + E + + + + L +
Sbjct 3531 QLKVNLPPNDNYFFYVRATNASGTSEQSEAALISTRGTRFLLLRETAHPALQISANGTVI 3590
Query 637 VLFCFNKRDLIKKHIWPNVP 656
+ I + +P
Sbjct 3591 SFSERRRLTEIPSVLGEELP 3610
Score = 66.4 bits (160), Expect = 1e-09, Method: Composition-based stats.
Identities = 40/209 (19%), Positives = 67/209 (32%), Gaps = 14/209 (7%)
Query 208 TSDHINFDPVYKVK-PNPPHNLSVINSEELSSILKLTWT-NPSIKSVIILKYNIQYRTKD 265
S + + +V P PP S S+ + + W+ N Y ++ D
Sbjct 3360 DSSARSDQMLKQVAVPQPPRLEPQEPSSATSTTIAVYWSVNKEDVVDSFQVYCVEEPQDD 3419
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
+ S +DL+P Y + + G S SE A T
Sbjct 3420 QEINELVEEYRLTVKESCCIFEDLEPDRCYQVWVMAVNFTGC---SLPSERAIFRT---A 3473
Query 326 PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT-VNA 384
PS T + W+ P L+Y + L++++ +
Sbjct 3474 PSTPVIHVEDCTVCWN----TATVRWRPANPEATETYTLEYCRQHSPEGEGLRSFSGIKG 3529
Query 385 TKLTVNL-TNDRYLATLTVRNLVGKSDAA 412
+L VNL ND Y + N G S+ +
Sbjct 3530 HQLKVNLPPNDNYFFYVRATNASGTSEQS 3558
Score = 59.9 bits (143), Expect = 1e-07, Method: Composition-based stats.
Identities = 35/210 (17%), Positives = 69/210 (33%), Gaps = 24/210 (11%)
Query 120 IISGLPPE-KPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADC--KA 174
+ PP +P+ S + W +E ++ + ++ + + +
Sbjct 3372 VAVPQPPRLEPQEPS--SATSTTIAVYWSVNKEDVVDSFQVYCVEEPQDDQEINELVEEY 3429
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINS 233
+ SC + +VWV A N G + S+ +++ P+ P + V +
Sbjct 3430 RLTVKESCCIFEDLEPDRCYQVWVMAVNFTGCSLPSE----RAIFRTAPSTPV-IHVEDC 3484
Query 234 EELSSILKLTWTN--PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ + W P L+Y Q+ + S + + +L P
Sbjct 3485 TVCWNTATVRWRPANPEATETYTLEYCRQHSPEGEGLRS------FSGIKGHQLKVNLPP 3538
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
Y F +R G S+ SE A T
Sbjct 3539 NDNYFFYVRATNASGT---SEQSEAALIST 3565
>sp|P0C5H6|TUTLA_RAT Protein turtle homolog A OS=Rattus norvegicus
OX=10116 GN=Igsf9 PE=1 SV=1
Length=1179
Score = 70.3 bits (170), Expect = 7e-11, Method: Composition-based stats.
Identities = 53/315 (17%), Positives = 88/315 (28%), Gaps = 46/315 (15%)
Query 40 LHSNFTAVCVLKEKCMDYFHVNANYIVW-KTNHFTIPKEQYTIINRTASSVTFTDIASLN 98
+ + C + + W K + Q N +
Sbjct 432 VGRDLLIPCSAR-------GDPPPIVSWAKVGRGLQGQAQVDSNNSLILRPLTKEAHGRW 484
Query 99 IQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNF 158
N + + NVY G P N+S +V K W+ G + F
Sbjct 485 ECSARNAVAHVTISTNVYV----LGTSPHVVTNVS-VVPLPKGANVSWEPGFDGGYLQRF 539
Query 159 TLKSEWATHKFADCKAKRDTPTSCTVDYSTVY------FVNIEVWVEAENALGKVTSDHI 212
++ K D + + + + + + V A+N LG I
Sbjct 540 SVWY-TPLAKRPDRAHHDWVSLAVPMGATHLLVPGLQAYTQYQFSVLAQNKLGSGPFSEI 598
Query 213 NFD---------------PVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSVIILK 256
P P PP L + + L W P + +
Sbjct 599 VLSIPEGLPTTPAVPRLPPTEMPPPLSPPRGLVAV---RTPRGVLLHWDPPELIPERLDG 655
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y ++ R + + W + + A T V L Y FR+ + Y SD S
Sbjct 656 YILEGR-QGSQGWEILD-QGVAGTEIQLLVPGLIKDVLYEFRLVAFADS---YVSDPSNI 710
Query 317 ASGIT--YEDRPSKA 329
A+ T E PS+
Sbjct 711 ANISTSGLEVYPSRT 725
Score = 67.2 bits (162), Expect = 7e-10, Method: Composition-based stats.
Identities = 38/247 (15%), Positives = 76/247 (31%), Gaps = 26/247 (11%)
Query 200 AENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A NA+ VT S ++ PH ++ ++ L ++W P + +++
Sbjct 488 ARNAVAHVTISTNVYVLGTS------PHVVTNVSVVPLPKGANVSWE-PGFDGGYLQRFS 540
Query 259 IQYRT---KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD--W 313
+ Y + + V L+ +T+Y F + + G G +S+
Sbjct 541 VWYTPLAKRPDRAHHDWVSLAVPMGATHLLVPGLQAYTQYQFSVLAQNKLGSGPFSEIVL 600
Query 314 SEEASGITYEDRPS-----KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEV 368
S T P P + R V L W PP ++ Y +
Sbjct 601 SIPEGLPTTPAVPRLPPTEMPPPLSPPRGLVAVRTPRGVLLHWD--PPELIPERLDGYIL 658
Query 369 TLTRWKSHLQ--NYTVNATKLTVNLTND----RYLATLTVRNLVGKSDAAVLTIPACDFQ 422
+ + + V T++ + + Y L SD + + +
Sbjct 659 EGRQGSQGWEILDQGVAGTEIQLLVPGLIKDVLYEFRLVAFADSYVSDPSNIANISTSGL 718
Query 423 ATHPVMD 429
+P
Sbjct 719 EVYPSRT 725
Score = 64.1 bits (154), Expect = 5e-09, Method: Composition-based stats.
Identities = 45/295 (15%), Positives = 83/295 (28%), Gaps = 27/295 (9%)
Query 370 LTRWKSHLQNYTVNATKLTVNLTNDRY-LATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
+ R N + + LT + + + RN V + + T + H V
Sbjct 455 VGRGLQGQAQVDSNNSLILRPLTKEAHGRWECSARNAV--AHVTISTNVYVLGTSPHVVT 512
Query 429 DLKAFPKDNMLWVEWTT--PRESVKKYILEWCVLS-DKAPCITDWQQE-DGTVHRTYLRG 484
++ P V W ++++ + + L+ DW L
Sbjct 513 NVSVVPLPKGANVSWEPGFDGGYLQRFSVWYTPLAKRPDRAHHDWVSLAVPMGATHLLVP 572
Query 485 NLAESKCYLITVTPVYADGPGSPESIKAYLKQA----------------PPSKGPTVRTK 528
L Y +V G G I + + PP P
Sbjct 573 GLQAYTQYQFSVLAQNKLGSGPFSEIVLSIPEGLPTTPAVPRLPPTEMPPPLSPPRGLVA 632
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN--VDSSHTEYTLSSLTSDT 586
+L WD P ++ + Y + R ++ V + + + L D
Sbjct 633 VRTPRGVLLHWD--PPELIPERLDGYILEGRQGSQGWEILDQGVAGTEIQLLVPGLIKDV 690
Query 587 LYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCF 641
LY R+ A+ D D + + +P L + + CF
Sbjct 691 LYEFRLVAFADSYVSDPSNIANISTSGLEVYPSRTQLPGLLPQPVLAGVVGGVCF 745
Score = 54.1 bits (128), Expect = 6e-06, Method: Composition-based stats.
Identities = 36/242 (15%), Positives = 62/242 (26%), Gaps = 42/242 (17%)
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ G+ S + A + S + S + + W+ P G
Sbjct 478 KEAHGRWECSARNAVAHVTISTNVYVLGTSPHVVTNVSVVPLPKGANVSWE---PGFDGG 534
Query 362 KILDYEVTLTR-----------WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD 410
+ + V T W S + +Y ++ +N +G
Sbjct 535 YLQRFSVWYTPLAKRPDRAHHDWVSLAVPMGATHLLVPGLQAYTQYQFSVLAQNKLGSGP 594
Query 411 AAVLTI----------------PACDFQATHPVMDLKAFPKDNMLWVEWTTP---RESVK 451
+ + + P P L A + + W P E +
Sbjct 595 FSEIVLSIPEGLPTTPAVPRLPPTEMPPPLSPPRGLVAVRTPRGVLLHWDPPELIPERLD 654
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRT---YLRGNLAESKCYLITVTPVYADGPGSPE 508
YILE S W+ D V T L L + Y + P
Sbjct 655 GYILEGRQGSQG------WEILDQGVAGTEIQLLVPGLIKDVLYEFRLVAFADSYVSDPS 708
Query 509 SI 510
+I
Sbjct 709 NI 710
>sp|P15509|CSF2R_HUMAN Granulocyte-macrophage colony-stimulating
factor receptor subunit alpha OS=Homo sapiens OX=9606 GN=CSF2RA
PE=1 SV=1
Length=400
Score = 68.7 bits (166), Expect = 7e-11, Method: Composition-based stats.
Identities = 33/195 (17%), Positives = 63/195 (32%), Gaps = 14/195 (7%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATH----KFADCKAKRDTPTSCTVD 185
+N SC + M C W G + + L + + T C +D
Sbjct 122 QNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLD 181
Query 186 YSTVYFVNIEVWVEAENA-LGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ V + +G D + D + NPP N++V ++ + W
Sbjct 182 NLSGLTSRNYFLVNGTSREIGIQFFDSL-LDTKKIERFNPPSNVTVRC---NTTHCLVRW 237
Query 245 TNP---SIKSVIILKYNIQ-YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
P S + +Y + +R + + + + +P ++ +IR
Sbjct 238 KQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKIR 297
Query 301 CMKEDGKGYWSDWSE 315
+ WS WSE
Sbjct 298 AA-DVRILNWSSWSE 311
>sp|Q8QFX1|RIMB2_CHICK RIMS-binding protein 2 OS=Gallus gallus
OX=9031 GN=RIMBP2 PE=1 SV=1
Length=1325
Score = 70.3 bits (170), Expect = 8e-11, Method: Composition-based stats.
Identities = 46/329 (14%), Positives = 103/329 (31%), Gaps = 42/329 (13%)
Query 129 PKNLSCIVNEGKKMRCEWDGGRET---HLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P+ ++ I K + W+ ++ + + ++ ++
Sbjct 318 PRKITLIKQLAKSVIVGWEPPVVPPGWGTINSYNVLVDKEVRMNIALGSRTKAL----IE 373
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ + +++ G V P NL V N ++S+ +L+W
Sbjct 374 KLNISTCTYRISIQSITNKGNSDELQCTLLVGKDVVV-APSNLKVDNITQISA--ELSW- 429
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P+ + + + ++ + + + +LKP Y ++
Sbjct 430 LPTNSNYSHVIFL-----------NEEEFDIVKAASYKYHFFNLKPNMAYKVKVMAKPHQ 478
Query 306 GKGYWSDWSEEAS----GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
W E+ + + P+ P+ + T+Q+ WK P A G
Sbjct 479 M--PWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVRAGSTQATIQVSWKP-PALTATG 535
Query 362 -----KILDYEVTLTRWKSHLQNYTVNATKLTVNLTN----DRYLATLTVRNLVGKS-DA 411
+ Y V + + + A V L + T+ + G+S D+
Sbjct 536 TSHGANVTGYGV-YAKGQRVAEVIFPTAENTLVELMRLRNLEAKEVTVRTLSAQGESVDS 594
Query 412 AVLTIPAC--DFQATHPVMDLKAFPKDNM 438
+V IP+ + HP K+ P +
Sbjct 595 SVAAIPSDLLVPPSPHPRTAPKSKPLASA 623
Score = 57.9 bits (138), Expect = 4e-07, Method: Composition-based stats.
Identities = 40/277 (14%), Positives = 75/277 (27%), Gaps = 32/277 (12%)
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLT--VNLTNDRYLAT 399
Q ++V + W+ G I Y V + + L +N++ Y +
Sbjct 326 QLAKSVIVGWEPPVVPPGWGTINSYNVLVDKEVRMNIALGSRTKALIEKLNISTCTYRIS 385
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
+ G SD T+ P + W P S +++
Sbjct 386 IQSITNKGNSDELQCTLLVGKDVVVAPSNLKVDNITQISAELSW-LPTNSNYSHVI---F 441
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA-- 517
L+++ I Y NL + Y + V P + K+A
Sbjct 442 LNEEEFDIVK------AASYKYHFFNLKPNMAYKVKVMAKPHQMPWQLPLEQREKKEAFV 495
Query 518 --------PPSKGPTVRTKKVGKN-EAVLEWDQLPVDVQNGF-----IRNYTIFYRTIIG 563
PP+ V + + W P G + Y ++
Sbjct 496 EFSTLPAGPPAPPQDVTVRAGSTQATIQVSWKP-PALTATGTSHGANVTGYGVY--AKGQ 552
Query 564 NETAVNVDSSHTEYT-LSSLTSDTLYMVRMAAYTDEG 599
V ++ L L + V + + +G
Sbjct 553 RVAEVIFPTAENTLVELMRLRNLEAKEVTVRTLSAQG 589
Score = 40.2 bits (92), Expect = 0.13, Method: Composition-based stats.
Identities = 19/108 (18%), Positives = 43/108 (40%), Gaps = 6/108 (6%)
Query 497 TPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
+ V ++G G+ + + + + K ++ W+ V G I +Y +
Sbjct 293 SSVISNGAGTLDVNIDEIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTINSYNV 352
Query 557 FYRTIIGNETAVNVD-SSHTEYTLSSLTSDT-LYMVRMAAYTDEGGKD 602
++ E +N+ S T+ + L T Y + + + T++G D
Sbjct 353 ----LVDKEVRMNIALGSRTKALIEKLNISTCTYRISIQSITNKGNSD 396
>sp|Q9UPX0|TUTLB_HUMAN Protein turtle homolog B OS=Homo sapiens
OX=9606 GN=IGSF9B PE=2 SV=2
Length=1349
Score = 70.3 bits (170), Expect = 8e-11, Method: Composition-based stats.
Identities = 40/226 (18%), Positives = 75/226 (33%), Gaps = 18/226 (8%)
Query 122 SGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL---KSEWATHKFADCKAKRDT 178
G P P ++ V W+ G + E F++ ++++ H +
Sbjct 506 IGTSPHAPGSVRVQV-SMTTANVSWEPGYDGGYEQTFSVWMKRAQFGPHDWLSLPVPPGP 564
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINS---- 233
+ V A+N LG S+ + + + P + V
Sbjct 565 SWLLVDTLEPE--TAYQFSVLAQNKLGTSAFSEVVTVNTLAFPITTPEPLVLVTPPRCLI 622
Query 234 -EELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
+ L+W P+ S I +Y +++R A W + + T F +DL
Sbjct 623 ANRTQQGVLLSWLPPANHSFPIDRYIMEFRV--AERWELLD-DGIPGTEGEFFAKDLSQD 679
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
T Y FR+ + +D S+ S A + + P + P
Sbjct 680 TWYEFRVLAVMQDLI---SEPSNIAGVSSTDIFPQPDLTEDGLARP 722
Score = 60.3 bits (144), Expect = 8e-08, Method: Composition-based stats.
Identities = 83/659 (13%), Positives = 163/659 (25%), Gaps = 107/659 (16%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P+ + + T C F + W + ++ + +VT
Sbjct 146 PQYIEAKEGGSITMTCT-------AFGNPKPIVTWLKEGTLLGASGKYQVSDGSLTVTSV 198
Query 93 DIASLNIQLTCNILTFGQLEQNVYGITIISGLPP---EKPKNLSCIVNEGKKMRCEWDGG 149
TC + + V+ ++ PP P+N++ +++ + C
Sbjct 199 S-REDRGAYTCRAYSIQ--GEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTC----- 250
Query 150 RETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV-----NIEVWVEAENAL 204
R N T W + +D + + F + + N+L
Sbjct 251 RAEAYPGNLTYTWYWQDENVY-FQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSL 309
Query 205 GKVTSDHINFDPVY--KVKPNPPHNLSVI--------NSEELSSILKLTWTNPSIKSVII 254
G+ S Y +V PP + + + W
Sbjct 310 GRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRP---- 365
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
+ + W+ + ED + T + L +T C+ + G +
Sbjct 366 ------LQVEKNLGWTLM--EDGSIRIEEATEEALGTYT-------CVPYNTLGTMGQSA 410
Query 315 EEASGITYEDRPSKAPSFWYK-------IDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
+ + P + Y+ + P G + W+ +
Sbjct 411 PARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRKVGKPS--------- 461
Query 368 VTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV 427
+S + + D N+V + T + H
Sbjct 462 ------RSKHSALPSGSLQFRALSKEDHGEWECVATNVV--TSITASTHLTVIGTSPHAP 513
Query 428 MDLKAFPKDNMLWVEWTTPRESVKKYIL---EWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
++ V W + Y W + P L
Sbjct 514 GSVRVQVSMTTANVSWEPGYD--GGYEQTFSVWMKRAQFGPHDWLSLPVPPGPSW-LLVD 570
Query 485 NLAESKCYLITVTPVYADGPGSPESIKA--------YLKQAPPSK-GPTVRTKKVGKNEA 535
L Y +V G + + + P +
Sbjct 571 TLEPETAYQFSVLAQNKLGTSAFSEVVTVNTLAFPITTPEPLVLVTPPRCLIANRTQQGV 630
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIG-NETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
+L W LP + I Y + +R + + E+ L+ DT Y R+ A
Sbjct 631 LLSW--LPPANHSFPIDRYIMEFRVAERWELLDDGIPGTEGEFFAKDLSQDTWYEFRVLA 688
Query 595 Y---------TDEGGKDG---PEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCF 641
G P+ T A+ + IV +C + CF
Sbjct 689 VMQDLISEPSNIAGVSSTDIFPQPDLTEDGLARPVLAGIVATICFLAAAILFSTLAACF 747
>sp|P11799|MYLK_CHICK Myosin light chain kinase, smooth muscle
OS=Gallus gallus OX=9031 GN=Mylk PE=1 SV=2
Length=1906
Score = 69.9 bits (169), Expect = 9e-11, Method: Composition-based stats.
Identities = 37/177 (21%), Positives = 59/177 (33%), Gaps = 22/177 (12%)
Query 142 MRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAE 201
+ C W R+ E + + + C + E
Sbjct 1254 ITCTWMKFRKQIQENEYIKIENAENSSKLTISSTKQEHCGCY-------------TLVVE 1300
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT-NPSIKSVIILKYNIQ 260
N LG + + KP+PP + S+ SS L L+W + + Y ++
Sbjct 1301 NKLGSRQAQ---VNLTVVDKPDPPAG-TPCASDIRSSSLTLSWYGSSYDGGSAVQSYTVE 1356
Query 261 YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
+ W+ + T +SF VQDL+ EY FR+R G S SE
Sbjct 1357 IWNSVDNKWTDL----TTCRSTSFNVQDLQADREYKFRVRAANVYGISEPSQESEVV 1409
Score = 49.1 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 22/133 (17%), Positives = 40/133 (30%), Gaps = 4/133 (3%)
Query 379 NYTVNATKLTVNLTNDRYL--ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
N++KLT++ T + TL V N +G S A + + D + +
Sbjct 1274 ENAENSSKLTISSTKQEHCGCYTLVVENKLG-SRQAQVNLTVVDKPDPPAGTPCASDIRS 1332
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV 496
+ L + W + + V W ++ +L + Y V
Sbjct 1333 SSLTLSWYGSSYDGGSAVQSYTVEIWN-SVDNKWTDLTTCRSTSFNVQDLQADREYKFRV 1391
Query 497 TPVYADGPGSPES 509
G P
Sbjct 1392 RAANVYGISEPSQ 1404
Score = 44.8 bits (104), Expect = 0.005, Method: Composition-based stats.
Identities = 18/97 (19%), Positives = 34/97 (35%), Gaps = 6/97 (6%)
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSS 573
K PP+ P + + L W +++YT+ + ++ T + S
Sbjct 1317 KPDPPAGTP--CASDIRSSSLTLSW-YGSSYDGGSAVQSYTVEIWNSVDNKWTDLTTCRS 1373
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFT 609
T + + L +D Y R+ A G + E
Sbjct 1374 -TSFNVQDLQADREYKFRVRAANVYGISEPSQESEVV 1409
>sp|Q9P2J2|TUTLA_HUMAN Protein turtle homolog A OS=Homo sapiens
OX=9606 GN=IGSF9 PE=1 SV=2
Length=1179
Score = 69.9 bits (169), Expect = 9e-11, Method: Composition-based stats.
Identities = 50/315 (16%), Positives = 82/315 (26%), Gaps = 46/315 (15%)
Query 40 LHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIP-KEQYTIINRTASSVTFTDIASLN 98
+ C + + W + + Q + +
Sbjct 432 VGRELLIPCSAQ-------GDPPPVVSWTKVGRGLQGQAQVDSNSSLILRPLTKEAHGHW 484
Query 99 IQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNF 158
N + NVY G P N+S + W+ G + F
Sbjct 485 ECSASNAVARVATSTNVYV----LGTSPHVVTNVSVVALPKGA-NVSWEPGFDGGYLQRF 539
Query 159 TLKSEWATHKFADCKAKRDTPTSCTVDYSTVY------FVNIEVWVEAENALGKVTSDHI 212
++ K D + V + + + V A+N LG I
Sbjct 540 SVWY-TPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQPHTQYQFSVLAQNKLGSGPFSEI 598
Query 213 NFD---------------PVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSVIILK 256
P P PP L + + L W P + +
Sbjct 599 VLSAPEGLPTTPAAPGLPPTEIPPPLSPPRGLVAV---RTPRGVLLHWDPPELVPKRLDG 655
Query 257 YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEE 316
Y ++ R + + W + P A T + V L Y FR+ SD S
Sbjct 656 YVLEGR-QGSQGWEVLDPA-VAGTETELLVPGLIKDVLYEFRLVAFAGSFV---SDPSNT 710
Query 317 ASGIT--YEDRPSKA 329
A+ T E PS+
Sbjct 711 ANVSTSGLEVYPSRT 725
Score = 68.3 bits (165), Expect = 3e-10, Method: Composition-based stats.
Identities = 51/329 (16%), Positives = 91/329 (28%), Gaps = 43/329 (13%)
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR 395
+ P QG + W + G+ L N++ + LT +
Sbjct 437 LIPCSAQGDPPPVVSWTKV------GRGLQ----------GQAQVDSNSSLILRPLTKEA 480
Query 396 Y-LATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT--PRESVKK 452
+ + N V + A T + H V ++ V W +++
Sbjct 481 HGHWECSASNAV--ARVATSTNVYVLGTSPHVVTNVSVVALPKGANVSWEPGFDGGYLQR 538
Query 453 YILEWCVLS-DKAPCITDWQQEDGTVHRTYLRG-NLAESKCYLITVTPVYADGPGSPESI 510
+ + + L+ DW V +L L Y +V G G I
Sbjct 539 FSVWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQPHTQYQFSVLAQNKLGSGPFSEI 598
Query 511 KAYLKQA----------------PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
+ PP P +L WD P ++ + Y
Sbjct 599 VLSAPEGLPTTPAAPGLPPTEIPPPLSPPRGLVAVRTPRGVLLHWD--PPELVPKRLDGY 656
Query 555 TIFYRTIIGNETAVN--VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
+ R ++ V + TE + L D LY R+ A+ D +
Sbjct 657 VLEGRQGSQGWEVLDPAVAGTETELLVPGLIKDVLYEFRLVAFAGSFVSDPSNTANVSTS 716
Query 613 FAQGEIEAIVVPVCLAFLLTTLLGVLFCF 641
+ +P L + + CF
Sbjct 717 GLEVYPSRTQLPGLLPQPVLAGVVGGVCF 745
Score = 66.0 bits (159), Expect = 1e-09, Method: Composition-based stats.
Identities = 42/245 (17%), Positives = 74/245 (30%), Gaps = 22/245 (9%)
Query 200 AENALGKV-TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
A NA+ +V TS ++ PH ++ ++ L ++W P + +++
Sbjct 488 ASNAVARVATSTNVYVLGTS------PHVVTNVSVVALPKGANVSWE-PGFDGGYLQRFS 540
Query 259 IQYRT---KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD--W 313
+ Y + + V L+P T+Y F + + G G +S+
Sbjct 541 VWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQPHTQYQFSVLAQNKLGSGPFSEIVL 600
Query 314 SEEASGITYEDRP-----SKAPSFWYKIDPSHTQGYRTVQLVWKT--LPPFEANGKILDY 366
S T P P + R V L W L P +G +L+
Sbjct 601 SAPEGLPTTPAAPGLPPTEIPPPLSPPRGLVAVRTPRGVLLHWDPPELVPKRLDGYVLEG 660
Query 367 EVTLTRWKSHLQNYTVNATKLTVNLTNDR--YLATLTVRNLVGKSDAAVLTIPACDFQAT 424
W+ T+L V Y L SD + +
Sbjct 661 RQGSQGWEVLDPAVAGTETELLVPGLIKDVLYEFRLVAFAGSFVSDPSNTANVSTSGLEV 720
Query 425 HPVMD 429
+P
Sbjct 721 YPSRT 725
Score = 59.9 bits (143), Expect = 9e-08, Method: Composition-based stats.
Identities = 34/240 (14%), Positives = 61/240 (25%), Gaps = 42/240 (18%)
Query 302 MKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANG 361
+ G S + A T + S + S + + W+ P G
Sbjct 478 KEAHGHWECSASNAVARVATSTNVYVLGTSPHVVTNVSVVALPKGANVSWE---PGFDGG 534
Query 362 KILDYEVTLTR-----------WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD 410
+ + V T W S + + +Y ++ +N +G
Sbjct 535 YLQRFSVWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQPHTQYQFSVLAQNKLGSGP 594
Query 411 AAVLTI----------------PACDFQATHPVMDLKAFPKDNMLWVEWTTP---RESVK 451
+ + + P P L A + + W P + +
Sbjct 595 FSEIVLSAPEGLPTTPAAPGLPPTEIPPPLSPPRGLVAVRTPRGVLLHWDPPELVPKRLD 654
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRT---YLRGNLAESKCYLITVTPVYADGPGSPE 508
Y+LE S W+ D V T L L + Y + P
Sbjct 655 GYVLEGRQGSQG------WEVLDPAVAGTETELLVPGLIKDVLYEFRLVAFAGSFVSDPS 708
>sp|Q9JHX3|IL21R_MOUSE Interleukin-21 receptor OS=Mus musculus
OX=10090 GN=Il21r PE=2 SV=1
Length=529
Score = 69.1 bits (167), Expect = 1e-10, Method: Composition-based stats.
Identities = 37/216 (17%), Positives = 73/216 (34%), Gaps = 21/216 (10%)
Query 131 NLSCIVNEGKKMRC--EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS- 187
+L+C + + C E + L + + E + C R + + Y+
Sbjct 22 DLTCYTDYLWTITCVLETRSPNPSILSLTWQDEYEELQDQETFCSLHRSGHNTTHIWYTC 81
Query 188 ----TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
+ + + V + G + + +F +KP PP N++V S ++
Sbjct 82 HMRLSQFLSDEVFIVNVTDQSGNNSQECGSFVLAESIKPAPPLNVTVAFSGRYD----IS 137
Query 244 WTNPSIKSVII-----LKYNIQYRTKDAS--TWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
W + + L+Y +QYR S S ++ + Y
Sbjct 138 WDSAYDEPSNYVLRGKLQYELQYRNLRDPYAVRPVTKLISVDSRNVSLLPEEFHKDSSYQ 197
Query 297 FRIRCMKEDG---KGYWSDWSEEASGITYEDRPSKA 329
++R + G +G WS+WS+ T P
Sbjct 198 LQVRAAPQPGTSFRGTWSEWSDPVIFQTQAGEPEAG 233
Score = 49.1 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 49/341 (14%), Positives = 101/341 (30%), Gaps = 37/341 (11%)
Query 433 FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAP-CITDWQQEDGTVHRTYLRGNLAESKC 491
P ++L + W E+ L D+ C + T L++
Sbjct 41 SPNPSILSLTWQD----------EYEELQDQETFCSLHRSGHNTTHIWYTCHMRLSQFLS 90
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFI 551
+ + V + + +++ P + + WD + N +
Sbjct 91 DEVFIVNVTDQSGNNSQECGSFVLAESIKPAPPLNVTVAFSGRYDISWDSAYDEPSNYVL 150
Query 552 RN---YTIFYR------TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
R Y + YR + ++VDS + D+ Y +++ A G
Sbjct 151 RGKLQYELQYRNLRDPYAVRPVTKLISVDSRNVSLLPEEFHKDSSYQLQVRAAPQPGTSF 210
Query 603 -GPEFTFTTPKFAQGEIEAIVVPV------CLAFLLTTLLGVLFCFNKRDLIKKHIWPNV 655
G ++ P Q + LA L+ L+ + + + K IW V
Sbjct 211 RGTWSEWSDPVIFQTQAGEPEAGWDPHMLLLLAVLIIVLVFMGLKIHLPWRLWKKIWAPV 270
Query 656 PDP-------SKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDL 708
P P + H + +S + + T + + +K FP
Sbjct 271 PTPESFFQPLYREHSGNFKKWVNTPFTASSIELVPQSSTTTSALHLSLYPAKEKKFPGLP 330
Query 709 KSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENES 749
+ + + ++ GH I + S S + +
Sbjct 331 GLEEQLECDGMSEPGHWCII---PLAAGQAVSAYSEERDRP 368
>sp|B4KJW1|IHOG_DROMO Interference hedgehog OS=Drosophila mojavensis
OX=7230 GN=iHog PE=3 SV=1
Length=897
Score = 69.5 bits (168), Expect = 1e-10, Method: Composition-based stats.
Identities = 68/472 (14%), Positives = 136/472 (29%), Gaps = 98/472 (21%)
Query 244 WTNPS------IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
W++P +L Y +Q + P+DT T + ++P E+
Sbjct 284 WSSPDVTGAVYNNRTRVLPYGLQI--------GGLQPKDT-GTYICYLDNGIRPALEHYI 334
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW------ 351
++ + ++ +T E + + G T ++ W
Sbjct 335 QLVVQQAPRI-----VRPPSANLTNEGE--------FMVLECAATGTPTPKIYWLLNGEN 381
Query 352 ---KTLPPFEANGKILDYEVT------LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTV 402
T ANG ++ V + + ++ T L VN T + +
Sbjct 382 SVYDTESELPANGSLILRRVQKRHAGCVQCFARNVLGEDSAGTLLQVNPTQIQAGDGMGT 441
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES---VKKYILEWCV 459
+ S+ + D + + W + ++ + +++ +
Sbjct 442 GGMGRSSNRNAHNRKQKQMVPPSAPNVTRL--SDESVMLRWHVVKNDGLHIQFFKVQYRM 499
Query 460 LSDKAPCITDWQQEDGTVHRTYLR--------------GNLAESKCYLITVTPV--YADG 503
WQ + + R L Y + V D
Sbjct 500 TDSGKR--KSWQTTNENIPYGKQRHDSDEAVRNFTSSVTGLRPDHSYRFRIMAVYSNNDN 557
Query 504 PGSPESIKAYLKQAP---PSKGPTV-RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYR 559
S S K +L++ P P + K+ + +L W LP D I Y +YR
Sbjct 558 KESNTSGKFFLQRGAALAPLPVPELLDIKEYSQTAVMLHW-HLPSDADEQLISGYYAYYR 616
Query 560 T--IIGNETAVNVD-SSHTEYTLSSLTSDTLYMVRMAAYTD----------EGGKDGPEF 606
G +D + +S+L T+Y ++ +++ +G P
Sbjct 617 PSASAGEYLKATIDGAKARSALISALEPGTIYEFKLQSFSAMAASEFSSLKQGRTQRPRS 676
Query 607 T-----------FTTPKFAQG---EIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
+ TTP + A L+ ++ C KR
Sbjct 677 STTAQPTMHTVDTTTPTHNETFNMNPLLTGTISGGALLILLVISACLCLCKR 728
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 40/237 (17%), Positives = 67/237 (28%), Gaps = 32/237 (14%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS---TWSQIPPEDTAST 280
PP +V + S + L W + I + +QYR D+ +W
Sbjct 462 PPSAPNVTRLSDES--VMLRWHVVKNDGLHIQFFKVQYRMTDSGKRKSWQTTNENIPYGK 519
Query 281 RSS----------FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED-RPSKA 329
+ +V L+P Y FRI + + S+ S + P
Sbjct 520 QRHDSDEAVRNFTSSVTGLRPDHSYRFRIMAVYSNNDNKESNTSGKFFLQRGAALAPLPV 579
Query 330 PSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN------ 383
P + S T V L W LP I Y S +
Sbjct 580 PELLDIKEYSQT----AVMLHW-HLPSDADEQLISGYYAYYRPSASAGEYLKATIDGAKA 634
Query 384 -ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNML 439
+ ++ Y L + + S+ + L + P A P + +
Sbjct 635 RSALISALEPGTIYEFKLQSFSAMAASEFSSL----KQGRTQRPRSSTTAQPTMHTV 687
Score = 48.7 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 33/208 (16%), Positives = 58/208 (28%), Gaps = 24/208 (12%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-----TNFTLKSEWATHKFADCKAKRDT 178
+PP P N++ + +E + W + L + + +
Sbjct 461 VPPSAP-NVTRLSDE--SVMLRWHVVKNDGLHIQFFKVQYRMTDSGKRKSWQTTNENIPY 517
Query 179 PTSCTVDYSTVYFVN-----------IEVWVEAE--NALGKVTSDHINFDPVYKVKPNP- 224
V + A N K ++ F P
Sbjct 518 GKQRHDSDEAVRNFTSSVTGLRPDHSYRFRIMAVYSNNDNKESNTSGKFFLQRGAALAPL 577
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P + E + + L W PS +I Y YR ++ D A R S
Sbjct 578 PVPELLDIKEYSQTAVMLHWHLPSDADEQLISGYYAYYRPSASAGEYLKATIDGAKAR-S 636
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
+ L+P T Y F+++ +S
Sbjct 637 ALISALEPGTIYEFKLQSFSAMAASEFS 664
>sp|E9Q612|PTPRO_MOUSE Receptor-type tyrosine-protein phosphatase
O OS=Mus musculus OX=10090 GN=Ptpro PE=1 SV=1
Length=1226
Score = 69.5 bits (168), Expect = 1e-10, Method: Composition-based stats.
Identities = 71/493 (14%), Positives = 139/493 (28%), Gaps = 60/493 (12%)
Query 135 IVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNI 194
+M W + F + E F D + + +
Sbjct 348 FSAFPVQMTLSWLPPKPPTAFDGFNILIE-REENFTDYLTVDEEAHEFVAELKEPGKYKL 406
Query 195 EVWVEAENAL------GKVTSDHINFDPVYK---VKPNPPHNLSVINSEELSSILKLTWT 245
V + + S P + P ++SV S+ ++WT
Sbjct 407 SVTTFSSSGACETRKSQSAKSLSFYISPTGEWIEELTEKPQHVSVHVL--SSTTALMSWT 464
Query 246 NPSIK-SVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ + I+ K + T S +++L P +Y + K
Sbjct 465 SSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKG 524
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
G SD +T+ P+ G V L W G
Sbjct 525 PLIGPPSDP------VTFAIVPTGIKDLMLY-----PLGPTAVVLSWTRP----ILGVFR 569
Query 365 DYEVTL---------TRWKSH----LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDA 411
Y V + + W ++ + ++ L Y +T+ +
Sbjct 570 KYVVEMFYFNPTTMTSEWTTYYEIAATVSLTASVRIASLLPAWYYNFRVTMVTWGDPELS 629
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP---RESVKKYILEWCVLSDKAPCIT 468
+ A +++L++ WT + +L W V+++ I
Sbjct 630 CCDSSTISFITAPVAPEITSVEYFNSLLYISWTYGDATTDLSHSRMLHWMVVAEGRKKIK 689
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTK 528
+ V L L Y ++VT G + L+ APP ++
Sbjct 690 --KSVTRNVMTAILS--LPPGDIYNLSVTACTERGSNTSLPRLVKLEPAPPK---SLFAV 742
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNETAV--NVDSSHTEYTLSSLTSD 585
+ L W + G + +F + + G+ + V S T+SSL
Sbjct 743 NKTQTSVTLLWVE------EGVADFFEVFCQQLGSGHNGKLQEPVAVSSHVVTISSLLPA 796
Query 586 TLYMVRMAAYTDE 598
T Y + +++ +
Sbjct 797 TAYNCSVTSFSHD 809
Score = 61.0 bits (146), Expect = 5e-08, Method: Composition-based stats.
Identities = 92/559 (16%), Positives = 160/559 (29%), Gaps = 97/559 (17%)
Query 147 DGGRET------HLETNFTLKSE-----WATHKFADCKAKRDTPTSCTVDYST--VYFVN 193
ET H + + S W F K ++ + + N
Sbjct 130 KPSPETGVLFEIHYPEKYNVFSRVNISYWEGRDFRTMLYKDFFKGKTVFNHWLPGLCYSN 189
Query 194 IEVWVEAENALGKVT----SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS- 248
I + +E K T S + ++ P PP N+SV + W PS
Sbjct 190 ITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPRNISVRFVNLNKN----NWEEPSG 245
Query 249 --------IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF---TEYVF 297
+ + ++ + + + PP + +S V P T+Y
Sbjct 246 SFPEDSFIKPPQDSIGRDRRFHFPEETP--ETPPSNVSSGSPPSNVSSAWPDPNSTDYE- 302
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP-SFWYKIDPSHTQGYRT---------V 347
+ +W D S A+ ED S P + + T+ +
Sbjct 303 ------STSQPFWWD-SASAAPENEEDFVSALPADYDTETTLDRTEKPTADPFSAFPVQM 355
Query 348 QLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN--ATKLTVNLTN-DRYLATLTVRN 404
L W P A + + + R ++ TV+ A + L +Y ++T +
Sbjct 356 TLSWLPPKPPTA---FDGFNILIEREENFTDYLTVDEEAHEFVAELKEPGKYKLSVTTFS 412
Query 405 LVG-----KSDAA------VLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKK 452
G KS +A + + T + + WT+ +E+
Sbjct 413 SSGACETRKSQSAKSLSFYISPTGEWIEELTEKPQHVSVHVLSSTTALMSWTSSQENYNS 472
Query 453 YILEWCVLS---DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES 509
I+ L+ K + Q + NL Y + + G P
Sbjct 473 TIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGPLIGPPSD 532
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI--FY---RTIIGN 564
+ P+ + +G VL W + + G R Y + FY T+
Sbjct 533 PVTFA--IVPTGIKDLMLYPLGPTAVVLSWTRPIL----GVFRKYVVEMFYFNPTTMTSE 586
Query 565 ET---AVNVDSSHT-EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEA 620
T + S T ++SL Y R+ T PE + I
Sbjct 587 WTTYYEIAATVSLTASVRIASLLPAWYYNFRVTMVT----WGDPELSCC----DSSTISF 638
Query 621 IVVPVCLAFLLTTLLGVLF 639
I PV L
Sbjct 639 ITAPVAPEITSVEYFNSLL 657
Score = 53.7 bits (127), Expect = 8e-06, Method: Composition-based stats.
Identities = 66/421 (16%), Positives = 122/421 (29%), Gaps = 42/421 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
EKP+++S V W +E + T ++ S + + ++ T
Sbjct 444 EKPQHVSVHVLSSTTALMSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSK 503
Query 187 STVYFVNIEVWVEAENALGKV-----TSDHINFDPVYKVKPNPPHNLS-VINSEELSSIL 240
+ + + L K SD + F V P + ++ + +
Sbjct 504 PVIENLVPGAQYQVVMYLRKGPLIGPPSDPVTFAIV-------PTGIKDLMLYPLGPTAV 556
Query 241 KLTWTNPSIKSVIILKYNIQ---YRTKD-ASTWSQ-IPPEDTASTRSSFTVQDLKPFTEY 295
L+WT P + + KY ++ + S W+ T S +S + L P Y
Sbjct 557 VLSWTRPIL--GVFRKYVVEMFYFNPTTMTSEWTTYYEIAATVSLTASVRIASLLPAWYY 614
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ-LVWKTL 354
FR+ + S S IT P + + + + ++ + W
Sbjct 615 NFRVTMVTWGDPELSCCDSSTISFITAPVAP----------EITSVEYFNSLLYISWTYG 664
Query 355 PPFEAN--GKILDYEVTLTRWKSHLQNYTVNA-TKLTVNLTNDRYLATLTVRNLVGKSDA 411
++L + V K ++ T N T + D Y ++T G +
Sbjct 665 DATTDLSHSRMLHWMVVAEGRKKIKKSVTRNVMTAILSLPPGDIYNLSVTACTERG---S 721
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
+ P + + W E V + +C Q
Sbjct 722 NTSLPRLVKLEPAPPKSLFAVNKTQTSVTLLW--VEEGVADFFEVFCQQLGSGHN-GKLQ 778
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
+ +L + Y +VT D P P I P V V
Sbjct 779 EPVAVSSHVVTISSLLPATAYNCSVTSFSHDTPSVPTFIAVST--MVTEVNPNVVVISVL 836
Query 532 K 532
Sbjct 837 A 837
Score = 52.2 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 57/378 (15%), Positives = 116/378 (31%), Gaps = 30/378 (8%)
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
L+W P + + R ++ + + + E + V +LK +Y +
Sbjct 356 TLSWLPPKPPTAFDGFNILIEREENFTDYLTVDEE------AHEFVAELKEPGKYKLSVT 409
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ----GYRTVQLVWKTLPP 356
G + S+ A +++ P+ P H T + W +
Sbjct 410 TFSSSGACE-TRKSQSAKSLSFYISPTGEWIEELTEKPQHVSVHVLSSTTALMSWTS-SQ 467
Query 357 FEANGKILDYEVTLTRWKSHLQN-------YTVNATKLTVNLTNDRYLATLTVRNLVGKS 409
N I+ V+LT K VN++K + + + G
Sbjct 468 ENYNSTIVS-VVSLTCQKQKESQRLEKQYCTQVNSSKPVIENLVPGAQYQVVMYLRKGP- 525
Query 410 DAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESV-KKYILE--WCVLSDKAP 465
+ P + DL +P + + WT P V +KY++E + +
Sbjct 526 LIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPILGVFRKYVVEMFYFNPTTMTS 585
Query 466 CITDWQQEDGTV--HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
T + + TV + +L + Y VT V P + + P
Sbjct 586 EWTTYYEIAATVSLTASVRIASLLPAWYYNFRVTMVTWGDPELSCCDSSTISFITAPVAP 645
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT-LSSL 582
+ + + + + W R + + + + + T + SL
Sbjct 646 EITSVEYFNSLLYISWTYGDATTDLSHSR--MLHWMVVAEGRKKIKKSVTRNVMTAILSL 703
Query 583 TSDTLYMVRMAAYTDEGG 600
+Y + + A T+ G
Sbjct 704 PPGDIYNLSVTACTERGS 721
>sp|Q8N3K9|CMYA5_HUMAN Cardiomyopathy-associated protein 5 OS=Homo
sapiens OX=9606 GN=CMYA5 PE=1 SV=3
Length=4069
Score = 69.5 bits (168), Expect = 1e-10, Method: Composition-based stats.
Identities = 37/248 (15%), Positives = 75/248 (30%), Gaps = 17/248 (7%)
Query 404 NLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDK 463
+ +SD + + P + V W+ +E V +C+ +
Sbjct 3690 DSSARSDQMLKQVAVPQPPRLEPQE--PNSATSTTIAVYWSMNKEDVIDSFQVYCMEEPQ 3747
Query 464 APCITDWQQEDGTVH---RTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPS 520
+ E+ + + +L +CY + V V G P + + PS
Sbjct 3748 DDQEVNELVEEYRLTVKESYCIFEDLEPDRCYQVWVMAVNFTGCSLPSERAIF--RTAPS 3805
Query 521 KGPTVRTKKVG--KNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETAVNVDSSHTEY 577
P +R + N A + W + YT+ Y R + S
Sbjct 3806 T-PVIRAEDCTVCWNTATIRWRPTTPEATE----TYTLEYCRQHSPEGEGLRSFSGIKGL 3860
Query 578 TLS-SLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLG 636
L +L + Y + A G + E + + + + L + ++
Sbjct 3861 QLKVNLQPNDNYFFYVRAINAFGTSEQSEAALISTRGTRFLLLRETAHPAL-HISSSGTV 3919
Query 637 VLFCFNKR 644
+ F +R
Sbjct 3920 ISFGERRR 3927
Score = 63.3 bits (152), Expect = 1e-08, Method: Composition-based stats.
Identities = 41/241 (17%), Positives = 77/241 (32%), Gaps = 25/241 (10%)
Query 208 TSDHINFDPVYKVK-PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTK-- 264
S + + +V P PP + S+ + + W+ K +I + + +
Sbjct 3690 DSSARSDQMLKQVAVPQPPRLEPQEPNSATSTTIAVYWSM--NKEDVIDSFQVYCMEEPQ 3747
Query 265 -DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
D + S +DL+P Y + + G S SE A T
Sbjct 3748 DDQEVNELVEEYRLTVKESYCIFEDLEPDRCYQVWVMAVNFTGC---SLPSERAIFRT-- 3802
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT-V 382
PS T + W+ P L+Y + L++++ +
Sbjct 3803 -APSTPVIRAEDCTVCWN----TATIRWRPTTPEATETYTLEYCRQHSPEGEGLRSFSGI 3857
Query 383 NATKLTVNL-TNDRYLATLTVRNLVGKSDAAVLTIPACDF-------QATHPVMDLKAFP 434
+L VNL ND Y + N G S+ + + + + HP + + +
Sbjct 3858 KGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAALISTRGTRFLLLRETAHPALHISSSG 3917
Query 435 K 435
Sbjct 3918 T 3918
Score = 53.7 bits (127), Expect = 1e-05, Method: Composition-based stats.
Identities = 32/210 (15%), Positives = 68/210 (32%), Gaps = 24/210 (11%)
Query 120 IISGLPPE-KPKNLSCIVNEGKKMRCEWDGGRETHLE--TNFTLKSEWATHKFADC--KA 174
+ PP +P+ + W +E ++ + ++ + + +
Sbjct 3702 VAVPQPPRLEPQEP--NSATSTTIAVYWSMNKEDVIDSFQVYCMEEPQDDQEVNELVEEY 3759
Query 175 KRDTPTSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINS 233
+ S + +VWV A N G + S+ +++ P+ P + +
Sbjct 3760 RLTVKESYCIFEDLEPDRCYQVWVMAVNFTGCSLPSE----RAIFRTAPSTPV-IRAEDC 3814
Query 234 EELSSILKLTWTN--PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
+ + W P L+Y Q+ + S + + +L+P
Sbjct 3815 TVCWNTATIRWRPTTPEATETYTLEYCRQHSPEGEGLRS------FSGIKGLQLKVNLQP 3868
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
Y F +R + G S+ SE A T
Sbjct 3869 NDNYFFYVRAINAFGT---SEQSEAALIST 3895
>sp|Q8R2Z5|VWA1_MOUSE von Willebrand factor A domain-containing
protein 1 OS=Mus musculus OX=10090 GN=Vwa1 PE=1 SV=1
Length=415
Score = 68.0 bits (164), Expect = 1e-10, Method: Composition-based stats.
Identities = 33/223 (15%), Positives = 64/223 (29%), Gaps = 13/223 (6%)
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP-RESVKKYILEWCVLSDKAPCIT 468
+ A P + + + W Y+LE ++ T
Sbjct 199 PIIARELRGSITDAMQPQQLHASEVLSSGFRLSWPPLLTADSGYYVLE--LVPSGKLATT 256
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL--KQAPPSKGPTVR 526
QQ G + +L Y +++ P P+ ++ ++A P + +
Sbjct 257 RRQQLPGNATS-WTWTDLDPDTDYEVSLLPESNVHLLRPQHVRVRTLQEEAGPER---IV 312
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA-VNVDSSHTEYTLSSLTSD 585
+ W P + + Y + + G V V + T+ LT
Sbjct 313 ISHARPRSLRVSW--APALGPDSAL-GYHVQLGPLQGGSLERVEVPAGQNSTTVQGLTPC 369
Query 586 TLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLA 628
T Y+V + A G + T A+ + P
Sbjct 370 TTYLVTVTAAFRSGRQRALSAKACTASGARTRAPQSMRPEAGP 412
Score = 56.0 bits (133), Expect = 8e-07, Method: Composition-based stats.
Identities = 26/181 (14%), Positives = 57/181 (31%), Gaps = 11/181 (6%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
+P+ L R W T + L+ + + + +
Sbjct 214 QPQQLHASEVLSSGFRLSW-PPLLTADSGYYVLELVPSGKLATTRRQQLPGNATSWTWTD 272
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFD-PVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ EV + E+ + + H+ + P ++ S L+++W
Sbjct 273 LDPDTDYEVSLLPESNVHLLRPQHVRVRTLQEEAGPE-----RIVISHARPRSLRVSWAP 327
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
L Y++Q + ++ + ++S TVQ L P T Y+ + G
Sbjct 328 ALGPDSA-LGYHVQLGPLQGGSLERVE---VPAGQNSTTVQGLTPCTTYLVTVTAAFRSG 383
Query 307 K 307
+
Sbjct 384 R 384
Score = 44.5 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 34/189 (18%), Positives = 63/189 (33%), Gaps = 9/189 (5%)
Query 348 QLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV--NLTNDRYLATLTVRNL 405
+L W L ++ +L+ + + Q NAT T + Y +L +
Sbjct 229 RLSWPPLLTADSGYYVLELVPSGKLATTRRQQLPGNATSWTWTDLDPDTDYEVSLLPESN 288
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT--PRESVKKYILEWCVLSDK 463
V + + +A P + + + L V W +S Y ++ L
Sbjct 289 VHLLRPQHVRVRTLQEEAG-PERIVISHARPRSLRVSWAPALGPDSALGYHVQ---LGPL 344
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP 523
+ + + T ++G L YL+TVT + G S KA ++ P
Sbjct 345 QGGSLERVEVPAGQNSTTVQG-LTPCTTYLVTVTAAFRSGRQRALSAKACTASGARTRAP 403
Query 524 TVRTKKVGK 532
+ G
Sbjct 404 QSMRPEAGP 412
>sp|B3MKS0|IHOG_DROAN Interference hedgehog OS=Drosophila ananassae
OX=7217 GN=iHog PE=3 SV=1
Length=880
Score = 69.1 bits (167), Expect = 2e-10, Method: Composition-based stats.
Identities = 48/287 (17%), Positives = 93/287 (32%), Gaps = 57/287 (20%)
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES---VKKYILEWCVLSDKAP 465
S A PA + P + + D + + W PR + + +++ + +
Sbjct 449 SKANRGRRPAQMIPPSAPNVTRLS---DESVMLRWMVPRNDGLAILFFKVQYRTVGEGKR 505
Query 466 CITDWQQEDGTVHR-------------TYLRGNLAESKCYLITVTPV--YADGPGSPESI 510
+WQ + + T +L + Y + V D S S
Sbjct 506 --KNWQTTNENIPYGRPEWNSEMGKSFTASVTDLKPQRTYRFRIMAVYTNNDNKESNMSA 563
Query 511 KAYLKQAP---PSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GN 564
K +L+ P P + + + VL W L D I Y +YR G
Sbjct 564 KFFLQPGAALDPMPVPEMLEIDEYSETAVVLHWR-LDSDADEQLITGYYAYYRPSSSAGE 622
Query 565 ETAVNVD-SSHTEYTLSSLTSDTLYMVRMAAYTDE----------GGKDGP--------- 604
++ +S +T+ +L + T+Y ++ +++ E G P
Sbjct 623 YFKATIEGASSRSFTIGNLEAGTVYEFKLQSFSAESASEFSALKQGRTQRPMVSTTEEAT 682
Query 605 ----EFTFTTPKFAQGEIEAIVVPVCL---AFLLTTLLGVLFCFNKR 644
TTP + + +V + A L+ ++ C +R
Sbjct 683 LQTGVRDTTTPSHNETFSMSPIVTGTIGGGAVLILFVVTTCLCMWRR 729
Score = 63.0 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 45/262 (17%), Positives = 77/262 (29%), Gaps = 30/262 (11%)
Query 193 NIEVWVEAENALGKVTSDHINFDPVYKVKPN---PPHNLSVINSEELSSILKLTWTNPSI 249
+++V + ++ SDH + +P PP +V + S + L W P
Sbjct 428 SLQVTPKPIHSESTQQSDHNHSKANRGRRPAQMIPPSAPNVTRLSDES--VMLRWMVPRN 485
Query 250 KSVIILKYNIQYRTKDAS---TWSQIPPEDTAS---------TRSSFTVQDLKPFTEYVF 297
+ IL + +QYRT W + +V DLKP Y F
Sbjct 486 DGLAILFFKVQYRTVGEGKRKNWQTTNENIPYGRPEWNSEMGKSFTASVTDLKPQRTYRF 545
Query 298 RIRCMKEDGKGYWSDWSEEASGITYEDR-PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
RI + + S+ S + P P + S T V L W+
Sbjct 546 RIMAVYTNNDNKESNMSAKFFLQPGAALDPMPVPEMLEIDEYSET----AVVLHWRLDSD 601
Query 357 FEANGKILDYEVTLTRWKSHLQNY-----TVNATKLTVNLT--NDRYLATLTVRNLVGKS 409
+ I Y S + + ++ T+ Y L + S
Sbjct 602 ADEQ-LITGYYAYYRPSSSAGEYFKATIEGASSRSFTIGNLEAGTVYEFKLQSFSAESAS 660
Query 410 DAAVLTIPACDFQATHPVMDLK 431
+ + L +
Sbjct 661 EFSALKQGRTQRPMVSTTEEAT 682
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 42/261 (16%), Positives = 77/261 (30%), Gaps = 38/261 (15%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHL-----ETNFTLKSEWATHKFADCKAKRDT 178
+PP P N++ + +E + W R L + + E +
Sbjct 461 IPPSAP-NVTRLSDE--SVMLRWMVPRNDGLAILFFKVQYRTVGEGKRKNWQTTNENIPY 517
Query 179 PTSCTVDYSTVYFV----------NIEVWVEA--ENALGKVTSDHINFDPVYKVKPNP-P 225
F + A N K ++ F +P P
Sbjct 518 GRPEWNSEMGKSFTASVTDLKPQRTYRFRIMAVYTNNDNKESNMSAKFFLQPGAALDPMP 577
Query 226 HNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
+ E + + L W S +I Y YR ++ ++ SF
Sbjct 578 VPEMLEIDEYSETAVVLHWRLDSDADEQLITGYYAYYRPSSSAG-EYFKATIEGASSRSF 636
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWS------------DWSEEASGITY---EDRPSKA 329
T+ +L+ T Y F+++ + +S +EEA+ T PS
Sbjct 637 TIGNLEAGTVYEFKLQSFSAESASEFSALKQGRTQRPMVSTTEEATLQTGVRDTTTPSHN 696
Query 330 PSFWYKIDPSHTQGYRTVQLV 350
+F + T G V ++
Sbjct 697 ETFSMSPIVTGTIGGGAVLIL 717
>sp|Q38J85|IL2RB_MACFA Interleukin-2 receptor subunit beta OS=Macaca
fascicularis OX=9541 GN=IL2RB PE=2 SV=1
Length=551
Score = 68.3 bits (165), Expect = 2e-10, Method: Composition-based stats.
Identities = 38/214 (18%), Positives = 69/214 (32%), Gaps = 16/214 (7%)
Query 132 LSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAK----RDTPTSC----- 182
+C N + C W ++ L+ W + + + +C
Sbjct 34 FTCFYNSRANISCVWS--QDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILG 91
Query 183 TVDYSTVYFVNI-EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
T D + V+I + V + +F P ++ P +L V++ E
Sbjct 92 TPDSQKLTAVDIVTLRVMCREGVRWRMMAIQDFKPFENLRLMAPISLQVVHVETH--RCN 149
Query 242 LTWTNPSIKSVIILKYNIQYRTKD-ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
++W + RT TW + P + ++ L P T+Y F++R
Sbjct 150 ISWKISQASHYFERHLEFEARTLSPGHTWEEAPLMTLKQKQEWICLETLTPDTQYEFQVR 209
Query 301 CMKEDG-KGYWSDWSEEASGITYEDRPSKAPSFW 333
G WS WS+ + T K W
Sbjct 210 VKPLQGEFTTWSPWSQPLAFRTKPAALGKDTIPW 243
Score = 37.5 bits (85), Expect = 0.56, Method: Composition-based stats.
Identities = 30/157 (19%), Positives = 53/157 (34%), Gaps = 20/157 (13%)
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET-----AVNVDSSHT 575
+++ V + + W F R+ RT+ T + +
Sbjct 134 APISLQVVHVETHRCNISWKISQASHY--FERHLEFEARTLSPGHTWEEAPLMTLKQKQE 191
Query 576 EYTLSSLTSDTLYMVRMAAYTDEG--GKDGPEFT---FTTPKFAQGE-------IEAIVV 623
L +LT DT Y ++ +G P F T A G+ + +
Sbjct 192 WICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDTIPWLGHLLVGL 251
Query 624 PVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK 660
F++ L ++ C N +KK + + PDPSK
Sbjct 252 SGAFGFIILVYL-LINCRNTGPWLKKVLKCHTPDPSK 287
>sp|Q9QZS7|NPHN_MOUSE Nephrin OS=Mus musculus OX=10090 GN=Nphs1
PE=1 SV=2
Length=1256
Score = 69.1 bits (167), Expect = 2e-10, Method: Composition-based stats.
Identities = 36/193 (19%), Positives = 64/193 (33%), Gaps = 19/193 (10%)
Query 132 LSCIVNEGKKMRCEW--DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTV 189
L C + W +G + +T + + +
Sbjct 875 LHCRARGVPNIDFTWTKNGVPLDLQDPRYTEHKYHQGVVHSSLLTIANVSAAQDYAL--- 931
Query 190 YFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
A NALG SDH N V +P+PP L V++ + L W P
Sbjct 932 ------FKCTATNALG---SDHTNIQLVSISRPDPPLGLKVVSV--SPHSVGLEWK-PGF 979
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY 309
+ ++ I+Y ++ + + + + ++FT+ LKP T Y + G
Sbjct 980 DGGLPQRFQIRYEALESPGF--LYMDVLPAQATTFTLTGLKPSTRYRIWLLASNALGDSG 1037
Query 310 WSDWSEEASGITY 322
+D + S T
Sbjct 1038 LTDKGIQVSITTP 1050
Score = 56.0 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 32/209 (15%), Positives = 63/209 (30%), Gaps = 14/209 (7%)
Query 30 YISPESPVVQLH---SNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTA 86
+ +P + V S+ T C + F N + + +Y +
Sbjct 856 HPTPLTKVAAAGDSTSSATLHCRARGVPNIDFTWTKNGVPLDLQDPRYTEHKYHQGVVHS 915
Query 87 SSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEW 146
S +T ++++ L + I ++S P+ P L + + EW
Sbjct 916 SLLTIANVSAAQDYALFKCTATNALGSDHTNIQLVSISRPDPPLGLKVVSVSPHSVGLEW 975
Query 147 DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG- 205
G + L F ++ E + +W+ A NALG
Sbjct 976 KPGFDGGLPQRFQIRYEALESPGFLYMDVLPAQATTFTLTGLKPSTRYRIWLLASNALGD 1035
Query 206 ----------KVTSDHINFDPVYKVKPNP 224
+T+ ++ P +P P
Sbjct 1036 SGLTDKGIQVSITTPGLDQAPEDTDQPLP 1064
Score = 54.5 bits (129), Expect = 5e-06, Method: Composition-based stats.
Identities = 33/162 (20%), Positives = 57/162 (35%), Gaps = 13/162 (8%)
Query 463 KAPCITDWQQEDGTVHRTYL-RGNLAESKCY-LITVTPVYADGPGSPESIKAYLKQAPPS 520
+ P T+ + G VH + L N++ ++ Y L T A G + + P
Sbjct 899 QDPRYTEHKYHQGVVHSSLLTIANVSAAQDYALFKCTATNALGSDHTNIQLVSI--SRPD 956
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN--VDSSHTEYT 578
++ V + LEW G + + I Y + + + T +T
Sbjct 957 PPLGLKVVSVSPHSVGLEW---KPGFDGGLPQRFQIRYEALESPGFLYMDVLPAQATTFT 1013
Query 579 LSSLTSDTLYMVRMAAYTDEGGKD----GPEFTFTTPKFAQG 616
L+ L T Y + + A G G + + TTP Q
Sbjct 1014 LTGLKPSTRYRIWLLASNALGDSGLTDKGIQVSITTPGLDQA 1055
>sp|Q28824|MYLK_BOVIN Myosin light chain kinase, smooth muscle
OS=Bos taurus OX=9913 GN=MYLK PE=1 SV=1
Length=1176
Score = 68.7 bits (166), Expect = 2e-10, Method: Composition-based stats.
Identities = 33/120 (28%), Positives = 50/120 (42%), Gaps = 9/120 (8%)
Query 197 WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT-NPSIKSVIIL 255
+ EN LG + + KP+PP + S+ SS L L+W + +
Sbjct 569 TLLVENKLGSRQAQ---VNLTVVDKPDPPAG-TPCASDIRSSSLTLSWYGSSYDGGSAVQ 624
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y+++ TW ++ +SF VQDL P EY FR+R + G S SE
Sbjct 625 SYSVEIWDSVDKTWKEL----ATCRSTSFNVQDLLPDREYKFRVRAINVYGTSEPSQESE 680
Score = 50.2 bits (118), Expect = 1e-04, Method: Composition-based stats.
Identities = 20/133 (15%), Positives = 40/133 (30%), Gaps = 4/133 (3%)
Query 379 NYTVNATKLTVNLTNDRYL--ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
+ +KLT+ + TL V N +G S A + + D + +
Sbjct 547 ENSEQGSKLTIRAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASDIRS 605
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV 496
+ L + W + + V W++ ++ +L + Y V
Sbjct 606 SSLTLSWYGSSYDGGSAVQSYSVEIWD-SVDKTWKELATCRSTSFNVQDLLPDREYKFRV 664
Query 497 TPVYADGPGSPES 509
+ G P
Sbjct 665 RAINVYGTSEPSQ 677
Score = 42.9 bits (99), Expect = 0.016, Method: Composition-based stats.
Identities = 20/148 (14%), Positives = 39/148 (26%), Gaps = 5/148 (3%)
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+ + + T CY + V ++ K PP+
Sbjct 539 QDSEHIKVENSEQGSKLTIRAARQEHCGCYTLLVENKLGSRQA-QVNLTVVDKPDPPAGT 597
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
P + + L W +++Y++ + T + + L
Sbjct 598 P--CASDIRSSSLTLSW-YGSSYDGGSAVQSYSVEIWDSVDKTWKELATCRSTSFNVQDL 654
Query 583 TSDTLYMVRMAAYTDEG-GKDGPEFTFT 609
D Y R+ A G + E T
Sbjct 655 LPDREYKFRVRAINVYGTSEPSQESELT 682
>sp|P16297|IL2RB_MOUSE Interleukin-2 receptor subunit beta OS=Mus
musculus OX=10090 GN=Il2rb PE=1 SV=1
Length=539
Score = 68.0 bits (164), Expect = 2e-10, Method: Composition-based stats.
Identities = 40/224 (18%), Positives = 74/224 (33%), Gaps = 25/224 (11%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKR------------- 176
+L C N + C W ++ T H C+
Sbjct 32 SHLECFYNSRANVSCMWSHEEALNVTTCHVHAKSNLRHWNKTCELTLVRQASWACNLILG 91
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
P S ++ + +N+ W E G +F P ++ PH+L V++ +
Sbjct 92 SFPESQSLTSVDLLDINVVCWEEK----GWRRVKTCDFHPFDNLRLVAPHSLQVLHID-- 145
Query 237 SSILKLTWTNPSIKSV--IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ ++W + L++ + R S W + ++ L P T
Sbjct 146 TQRCNISWKVSQVSHYIEPYLEFEARRRLLGHS-WEDASVLSLKQRQQWLFLEMLIPSTS 204
Query 295 YVFRIRCM-KEDGKGYWSDWSEEASGITYEDRPSK--APSFWYK 335
Y ++R + + G WS WS+ + T P K P W +
Sbjct 205 YEVQVRVKAQRNNTGTWSPWSQPLTFRTRPADPMKEILPMSWLR 248
Score = 47.2 bits (110), Expect = 7e-04, Method: Composition-based stats.
Identities = 39/229 (17%), Positives = 73/229 (32%), Gaps = 26/229 (11%)
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF--YRTIIGNE----TAVNVDSSH 574
+++ + + W V +I Y F R ++G+ + +++
Sbjct 135 APHSLQVLHIDTQRCNISWKVSQVSH---YIEPYLEFEARRRLLGHSWEDASVLSLKQRQ 191
Query 575 TEYTLSSLTSDTLYMV--RMAAYTDEGGKDGPEF---TFTTPKFAQGEIEAI-------- 621
L L T Y V R+ A + G P TF T +
Sbjct 192 QWLFLEMLIPSTSYEVQVRVKAQRNNTGTWSPWSQPLTFRTRPADPMKEILPMSWLRYLL 251
Query 622 VVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQ 681
+V C + + + ++ C +K + ++PDPS+ S H + S
Sbjct 252 LVLGCFSGFFSCVYILVKCRYLGPWLKTVLKCHIPDPSEFFSQLSSQHGGDLQKWLSSPV 311
Query 682 MYS----DGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSS 726
S G ++S +E+ D K L D + +S
Sbjct 312 PLSFFSPSGPAPEISPLEVLDGDSKAVQLLLLQKDSAPLPSPSGHSQAS 360
>sp|P14784|IL2RB_HUMAN Interleukin-2 receptor subunit beta OS=Homo
sapiens OX=9606 GN=IL2RB PE=1 SV=1
Length=551
Score = 68.0 bits (164), Expect = 2e-10, Method: Composition-based stats.
Identities = 37/214 (17%), Positives = 69/214 (32%), Gaps = 16/214 (7%)
Query 132 LSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAK----RDTPTSC----- 182
+C N + C W ++ L+ W + + + +C
Sbjct 34 FTCFYNSRANISCVWS--QDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILG 91
Query 183 TVDYSTVYFVNI-EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
D + V+I + V + +F P ++ P +L V++ E +
Sbjct 92 APDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVE--THRCN 149
Query 242 LTWTNPSIKSVIILKYNIQYRTKD-ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
++W + RT TW + P + ++ L P T+Y F++R
Sbjct 150 ISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVR 209
Query 301 CMKEDG-KGYWSDWSEEASGITYEDRPSKAPSFW 333
G WS WS+ + T K W
Sbjct 210 VKPLQGEFTTWSPWSQPLAFRTKPAALGKDTIPW 243
Score = 39.8 bits (91), Expect = 0.12, Method: Composition-based stats.
Identities = 41/228 (18%), Positives = 70/228 (31%), Gaps = 34/228 (15%)
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET-----AVNVDSSHT 575
+++ V + + W+ F R+ RT+ T + +
Sbjct 134 APISLQVVHVETHRCNISWEISQASHY--FERHLEFEARTLSPGHTWEEAPLLTLKQKQE 191
Query 576 EYTLSSLTSDTLYMVRMAAYTDEG--GKDGPEFT---FTTPKFAQGE-------IEAIVV 623
L +LT DT Y ++ +G P F T A G+ + +
Sbjct 192 WICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDTIPWLGHLLVGL 251
Query 624 PVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK-----SH-----IAQWSPHTPPR 673
F++ L + C N +KK + N PDPSK S + +W P
Sbjct 252 SGAFGFIILVYLLI-NCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPS 310
Query 674 HNFNSKDQMYSDGNFTDVSVVE----IEANDKKPFPEDLKSLDLFKKE 717
+F+ + + + DK P P L S
Sbjct 311 SSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSC 358
>sp|Q9HBE5|IL21R_HUMAN Interleukin-21 receptor OS=Homo sapiens
OX=9606 GN=IL21R PE=1 SV=1
Length=538
Score = 68.0 bits (164), Expect = 2e-10, Method: Composition-based stats.
Identities = 37/213 (17%), Positives = 76/213 (36%), Gaps = 23/213 (11%)
Query 131 NLSCIVNEGKKMRC---EWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
+L C + + + C W+ T T + + E + C R + Y+
Sbjct 22 DLVCYTDYLQTVICILEMWNLHPSTLTLT-WQDQYEELKDEATSCSLHRSAHNATHATYT 80
Query 188 -----TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKL 242
+ + V + G + + +F +KP PP N++V S + + +
Sbjct 81 CHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFSGQYN----I 136
Query 243 TWTNPSIKSVII-----LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK--PFTEY 295
+W + L+Y +QYR + + + S ++ L+ + Y
Sbjct 137 SWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSY 196
Query 296 VFRIRCMKEDG---KGYWSDWSEEASGITYEDR 325
++R G +G WS+WS+ T +
Sbjct 197 ELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEE 229
Score = 38.7 bits (88), Expect = 0.30, Method: Composition-based stats.
Identities = 38/258 (15%), Positives = 72/258 (28%), Gaps = 33/258 (13%)
Query 521 KGPTVRTKKVGKNEAVLEW----DQLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDS 572
P + + W + + G ++ Y + YR +
Sbjct 120 PAPPFNVTVTFSGQYNISWRSDYEDPAFYMLKGKLQ-YELQYRNRGDPWAVSPRRKLISV 178
Query 573 SHTEYTLSSLT--SDTLYMVRMAAYTDEGGK-DGPEFTFTTPKFAQGEIEAIVVPV---- 625
+L L D+ Y +++ A G G ++ P Q + E +
Sbjct 179 DSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHL 238
Query 626 -CLAFLLTTLLGVLFCFNKRDL--IKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQM 682
L L+ + + L + K IW VP P + P + S D
Sbjct 239 LLLLLLVIVFIPAFWSLKTHPLWRLWKKIW-AVPSPER--------FFMPLYKGCSGDFK 289
Query 683 YSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSS----R 738
G S +E+ + P L+ + + + + S +
Sbjct 290 KWVGAPFTGSSLELGPWSPE-VPSTLEVYSCHPPRSPAKRLQLTELQEPAELVESDGVPK 348
Query 739 PSISSSDENESSQNTSST 756
PS + +N S
Sbjct 349 PSFWPTAQNSGGSAYSEE 366
>sp|P26954|IL3B2_MOUSE Interleukin-3 receptor class 2 subunit
beta OS=Mus musculus OX=10090 GN=Csf2rb2 PE=1 SV=1
Length=878
Score = 68.0 bits (164), Expect = 3e-10, Method: Composition-based stats.
Identities = 57/321 (18%), Positives = 104/321 (32%), Gaps = 45/321 (14%)
Query 30 YISPESP----VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRT 85
++ P P + +F + +++ I ++ + + +
Sbjct 134 HVQPPPPKDIHISPSGDHFLLEWSVSLGDSQVSWLSSKDIEFEVAYKRLQDSWEDASSLH 193
Query 86 ASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPP---------------EKPK 130
S+ F + L +I + G ++ SG P +P+
Sbjct 194 TSN--FQVNLEPKLFLPNSIYAARVRTRLSAGSSL-SGRPSRWSPEVHWDSQPGDKAQPQ 250
Query 131 NLSCIVNEGKKMRCEWDGGRETHLETNFTLKS--------EWATHKFADCKAKRDTPTSC 182
NL C + + + C W+ +T +F L E + + +A T C
Sbjct 251 NLQCFFDGIQSLHCSWEVWTQTTGSVSFGLFYRPSPAAPEEKCSPVVKEPQASVYTRYRC 310
Query 183 TVD-YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
++ V V K Y ++ PP N + S
Sbjct 311 SLPVPEPSAHSQYTVSV-------KHLEQGKFIMSYYHIQMEPPILNQTKNRDSYS---- 359
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
L W I I + +QY+ K + +W E+ +S + L+P T Y R+R
Sbjct 360 LHWETQKIPKYIDHTFQVQYK-KKSESWKDSKTENL-GRVNSMDLPQLEPDTSYCARVRV 417
Query 302 MK-EDGKGYWSDWSEEASGIT 321
D G WS+WS E + T
Sbjct 418 KPISDYDGIWSEWSNEYTWTT 438
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 79/481 (16%), Positives = 142/481 (30%), Gaps = 62/481 (13%)
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA----NGKILDYEVTLTRWKSHLQN-YT 381
P I PS L W + K +++EV R + ++ +
Sbjct 136 QPPPPKDIHISPSGDHF----LLEWSVSLGDSQVSWLSSKDIEFEVAYKRLQDSWEDASS 191
Query 382 VNATKLTVNL------TNDRYLATLTVRNLVGKSDAAVLT----------IPACDFQATH 425
++ + VNL N Y A + R G S + + P Q +
Sbjct 192 LHTSNFQVNLEPKLFLPNSIYAARVRTRLSAGSSLSGRPSRWSPEVHWDSQPGDKAQPQN 251
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
+ W WT SV + + + +E T R +
Sbjct 252 LQCFFDGIQSLHCSWEVWTQTTGSVSFGLFYRPSPAAPEEKCSPVVKEPQASVYTRYRCS 311
Query 486 L---AESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD-- 540
L S TV+ + + S + P + + ++ L W+
Sbjct 312 LPVPEPSAHSQYTVSVKHLEQGKFIMSYYHIQME------PPILNQTKNRDSYSLHWETQ 365
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLY--MVRMAAYTDE 598
++P + + F Y ++ ++ L L DT Y VR+ +D
Sbjct 366 KIPKYIDHTFQVQYK--KKSESWKDSKTENLGRVNSMDLPQLEPDTSYCARVRVKPISDY 423
Query 599 GGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDP 658
G T +V + + + T LL + F + +P+P
Sbjct 424 DGIWSEWSNEYTWTTDWVMPTLWIVLILVFLIFTLLLALHFGRVYGYRTYRKWKEKIPNP 483
Query 659 SKSHIAQ------WSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLD 712
SKS + Q W P + F +K+ + A + E L+
Sbjct 484 SKSLLFQDGGKGLWPPGSMA--AFATKN------PALQGPQSRLLAEQQGVSYEHLE--- 532
Query 713 LFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVP 772
I SRP + + +ES++ + + S R Q+P
Sbjct 533 --DNNVSPLTIEDPNIIRDP---PSRPDTTPAASSESTEQLPNVQVEGPIPSSRPRKQLP 587
Query 773 S 773
S
Sbjct 588 S 588
Score = 43.7 bits (101), Expect = 0.008, Method: Composition-based stats.
Identities = 56/404 (14%), Positives = 116/404 (29%), Gaps = 58/404 (14%)
Query 130 KNLSCIVNEGKKMRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYST 188
K L C + ++ C W D L L + + C+ S
Sbjct 35 KTLECYNDYTNRIICSWADTEDAQGLINMTLLYHQLDKIQSVSCELSEKLMWSECPSSHR 94
Query 189 VY----FVNIEVWVEAENALGKVTSD-----HINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ + +N D + V+P PP ++ + S +
Sbjct 95 CVPRRCVIPYTRFSNGDNDYYSFQPDRDLGIQLMVPLAQHVQPPPPKDIHISPSGDH--- 151
Query 240 LKLTWTNP------SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
L W+ S S +++ + Y+ S W T++ + + + P +
Sbjct 152 FLLEWSVSLGDSQVSWLSSKDIEFEVAYKRLQDS-WEDASSLHTSNFQVNLEPKLFLPNS 210
Query 294 EYVFRIRCMKEDG---KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
Y R+R G G S WS E ++ +P + G +++
Sbjct 211 IYAARVRTRLSAGSSLSGRPSRWSPEVH---WDSQPGD--KAQPQNLQCFFDGIQSLHCS 265
Query 351 WKTLPPFEAN-GKILDY-------EVTLTRWKSHLQNYTVNATKLTVNLTNDR----YLA 398
W+ + L Y E + Q + ++ + Y
Sbjct 266 WEVWTQTTGSVSFGLFYRPSPAAPEEKCSPVVKEPQASVYTRYRCSLPVPEPSAHSQYTV 325
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI---- 454
++ + + Q P+++ + + W T + + KYI
Sbjct 326 SVKHL------EQGKFIMSYYHIQMEPPILNQT--KNRDSYSLHWETQK--IPKYIDHTF 375
Query 455 -LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT 497
+++ S+ D + E+ + L Y V
Sbjct 376 QVQYKKKSES---WKDSKTENLGRVNSMDLPQLEPDTSYCARVR 416
>sp|Q642A6|VWA1_RAT von Willebrand factor A domain-containing
protein 1 OS=Rattus norvegicus OX=10116 GN=Vwa1 PE=2 SV=1
Length=415
Score = 67.2 bits (162), Expect = 3e-10, Method: Composition-based stats.
Identities = 31/195 (16%), Positives = 58/195 (30%), Gaps = 13/195 (7%)
Query 410 DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP-RESVKKYILEWCVLSDKAPCIT 468
+ A P + N + W Y+LE ++ T
Sbjct 199 PIIARELRGAIIDAMQPHQLHASEILSNGFRLSWPPLLTADSGYYVLE--LVPSGKLAAT 256
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL--KQAPPSKGPTVR 526
QQ G + +L Y +++ P P+ ++ ++A P + +
Sbjct 257 RRQQLPGNATS-WTWTDLNPDTDYEVSLLPESNVRLLRPQHLRVRTLQEEAGPER---IV 312
Query 527 TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSD 585
+ W P + + Y + + G V V + T+ LT
Sbjct 313 ISHTRPRSLRVSW--APALGPDSTL-GYLVQLGPLQGGSLEHVEVPAGQNSTTIQGLTPC 369
Query 586 TLYMVRMAAYTDEGG 600
T Y+V + A G
Sbjct 370 TTYLVTVTAAFRSGR 384
Score = 57.9 bits (138), Expect = 2e-07, Method: Composition-based stats.
Identities = 27/181 (15%), Positives = 58/181 (32%), Gaps = 11/181 (6%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
+P L R W T + L+ + A + + +
Sbjct 214 QPHQLHASEILSNGFRLSW-PPLLTADSGYYVLELVPSGKLAATRRQQLPGNATSWTWTD 272
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFD-PVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+ EV + E+ + + H+ + P ++ S L+++W
Sbjct 273 LNPDTDYEVSLLPESNVRLLRPQHLRVRTLQEEAGPE-----RIVISHTRPRSLRVSWA- 326
Query 247 PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
P++ L Y +Q + + + ++S T+Q L P T Y+ + G
Sbjct 327 PALGPDSTLGYLVQLGPLQGGSLEHVE---VPAGQNSTTIQGLTPCTTYLVTVTAAFRSG 383
Query 307 K 307
+
Sbjct 384 R 384
Score = 46.4 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 34/171 (20%), Positives = 59/171 (35%), Gaps = 9/171 (5%)
Query 348 QLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN--DRYLATLTVRNL 405
+L W L ++ +L+ + + Q NAT T N Y +L +
Sbjct 229 RLSWPPLLTADSGYYVLELVPSGKLAATRRQQLPGNATSWTWTDLNPDTDYEVSLLPESN 288
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT--PRESVKKYILEWCVLSDK 463
V L + +A P + + + L V W +S Y+++ L
Sbjct 289 VRLLRPQHLRVRTLQEEAG-PERIVISHTRPRSLRVSWAPALGPDSTLGYLVQ---LGPL 344
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+ + + T ++G L YL+TVT + G S KA
Sbjct 345 QGGSLEHVEVPAGQNSTTIQG-LTPCTTYLVTVTAAFRSGRQRALSAKACT 394
>sp|O73791|TIE2_DANRE Angiopoietin-1 receptor OS=Danio rerio OX=7955
GN=tek PE=1 SV=1
Length=1116
Score = 68.0 bits (164), Expect = 3e-10, Method: Composition-based stats.
Identities = 60/377 (16%), Positives = 112/377 (30%), Gaps = 26/377 (7%)
Query 296 VFRIRCMKEDGKGYWSDWSEEASGITYED--RPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
VFR++ ++ G W ++ K P G R + L+
Sbjct 406 VFRVQQVRVSSAGRWRCQVNNTHMQVEDEFTVEVKVPPRPQNPPVLQGSGPRHLLLL-LN 464
Query 354 LPPFEANGKILDYEVTLTRWKSH-LQNYTVNATKLTVNLTN--DRYLATLTVRNLVGKSD 410
P+ +G I + +H + T + + ++ +YL + +
Sbjct 465 TEPYSGDGPIATTTLLYRPASAHTWSSVTAHGPLVRLDNLYPMTQYLTQVQLSRPGPGGA 524
Query 411 AAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWT-TPRESVKKYILEWCVLSDKAPCIT 468
Q + +K L + W P E Y + L AP
Sbjct 525 GQAGPAATFSTQVLELPVGVKLSAVSQTALLLSWDIAPAEQHCTYEV--SCLQAGAPGTL 582
Query 469 DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTK 528
Q +L L Y TV G P + L P +
Sbjct 583 RTFQLPSNSSAMHLSD-LKPRHKYQCTVRSSCGVGQNHPSASAWTLSDQLPPPPANISIW 641
Query 529 KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSS--HTEYTLSSLTSDT 586
+ AVL W + + + + + + + V + H + L L +T
Sbjct 642 NISDTSAVLTWAVAEGESVSRAVIRFQQVEQAQYRQQVELPVQTQQLHMRFQLLGLRPNT 701
Query 587 LYMVRMAAYTDEG--GKDGPEFTFTTPKF-------AQGEIEAIVVPVCLAFLLTTLLGV 637
Y +++ + G + P T P+ A G + + T+L +
Sbjct 702 GYQLQLWTVNNMGESAESPPVSLMTLPQQESSALFAAHGHLLLYAILGSAGMTCCTVL-L 760
Query 638 LFC---FNKRDLIKKHI 651
FC KR+ +++ I
Sbjct 761 AFCIVLQLKRNTLQRRI 777
Score = 59.1 bits (141), Expect = 2e-07, Method: Composition-based stats.
Identities = 51/331 (15%), Positives = 102/331 (31%), Gaps = 43/331 (13%)
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
F KV P P N V+ +L L T P I + YR A TWS +
Sbjct 435 FTVEVKVPPR-PQNPPVLQGSGPRHLLLLLNTEPYSGDGPIATTTLLYRPASAHTWSSV- 492
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
+ + +L P T+Y+ +++ + G + T+ + + P
Sbjct 493 ----TAHGPLVRLDNLYPMTQYLTQVQLSRPGPGGA----GQAGPAATFSTQVLELPVGV 544
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ----NYTVNATKLTV 389
S T + L W P + YEV+ + + N++ + +
Sbjct 545 KLSAVSQT----ALLLSWDIAPAEQH----CTYEVSCLQAGAPGTLRTFQLPSNSSAMHL 596
Query 390 NLTNDRYLATLTVRNLVGKS---DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEW--- 443
+ R+ TVR+ G +A + + + D + W
Sbjct 597 SDLKPRHKYQCTVRSSCGVGQNHPSASAWTLSDQLPPPPANISIWNI-SDTSAVLTWAVA 655
Query 444 --TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYA 501
+ +V ++ + + + +H + L + Y + + V
Sbjct 656 EGESVSRAVIRFQQVEQAQYRQQVELP---VQTQQLHMRFQLLGLRPNTGYQLQLWTVNN 712
Query 502 DGPGSPESIKAYLKQAPPSKGPTVRTKKVGK 532
G ++PP T+ ++
Sbjct 713 MGE---------SAESPPVSLMTLPQQESSA 734
Score = 54.5 bits (129), Expect = 5e-06, Method: Composition-based stats.
Identities = 35/211 (17%), Positives = 69/211 (33%), Gaps = 9/211 (4%)
Query 121 ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT 180
S E P + + WD T + + A + + +
Sbjct 533 FSTQVLELPVGVKLSAVSQTALLLSWDIAPAEQHCT-YEVSCLQAGAPGTLRTFQLPSNS 591
Query 181 SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
S + V + +G+ + ++ P PP N+S+ N + S++L
Sbjct 592 SAMHLSDLKPRHKYQCTVRSSCGVGQNHPSASAWTLSDQLPP-PPANISIWNISDTSAVL 650
Query 241 KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP-PEDTASTRSSFTVQDLKPFTEYVFRI 299
S ++++ + + A Q+ P T F + L+P T Y ++
Sbjct 651 TWAVAEGESVSRAVIRFQ---QVEQAQYRQQVELPVQTQQLHMRFQLLGLRPNTGYQLQL 707
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
+ G+ S S S +T + S A
Sbjct 708 WTVNNMGE---SAESPPVSLMTLPQQESSAL 735
>sp|P34082|FAS2_DROME Fasciclin-2 OS=Drosophila melanogaster OX=7227
GN=Fas2 PE=1 SV=1
Length=873
Score = 68.0 bits (164), Expect = 3e-10, Method: Composition-based stats.
Identities = 61/334 (18%), Positives = 106/334 (32%), Gaps = 45/334 (13%)
Query 131 NLSCIVNEGKKMRCEWD-GGRETHLETNFTLKSEWATH-KFADCKAKRDTPTSCTVDYST 188
NLSC+ EW GR+ +K + T+ K + D +
Sbjct 448 NLSCLAMGIPNATIEWHWNGRK--------IKDLYDTNLKIVGTGPRSDL---IVHPVTR 496
Query 189 VYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT--- 245
Y+ + A N G D + +V + + +T+
Sbjct 497 QYYSGYK--CIATNIHGTAEHDMQLKEA--RVP-----DFVSEAKPSQLTATTMTFDIRG 547
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
+ + IL Y++QY+ WS + S S + V+ L+P TEY FR +
Sbjct 548 PSTELGLPILAYSVQYKEALNPDWST-AYNRSWSPDSPYIVEGLRPQTEYSFRFAARNQV 606
Query 306 GKGYW---SDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT-VQLVWKTLPPFEANG 361
G G W S E +P P K +P Y +L W P +
Sbjct 607 GLGNWGVNQQQSTPRRSAPEEPKPLHNPVQHDKEEPVVVSPYSDHFELRWGV--PADNGE 664
Query 362 KILDYEVTLTRWKS-------------HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK 408
I Y++ ++ + ++T + N Y L N +G
Sbjct 665 PIDRYQIKYCPGVKISGTWTELENSCNTVEVMETTSFEMTQLVGNTYYRIELKAHNAIGY 724
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVE 442
S A + + V + + F ++ +
Sbjct 725 SSPASIIMKTTRGIDVIQVAERQVFSSAAIVGIA 758
Score = 59.5 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 29/182 (16%), Positives = 50/182 (27%), Gaps = 28/182 (15%)
Query 454 ILEWCVLSDKAPCITDWQ---QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS--PE 508
IL + V K DW + Y+ L Y G G+
Sbjct 556 ILAYSVQY-KEALNPDWSTAYNRSWSPDSPYIVEGLRPQTEYSFRFAARNQVGLGNWGVN 614
Query 509 SIKAYLKQAPPSKGPTVR-----------TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
++ +++ P + + + L W +P D I Y I
Sbjct 615 QQQSTPRRSAPEEPKPLHNPVQHDKEEPVVVSPYSDHFELRWG-VPADNGE-PIDRYQIK 672
Query 558 Y---------RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
Y T + N T + ++ L +T Y + + A+ G
Sbjct 673 YCPGVKISGTWTELENSCNTVEVMETTSFEMTQLVGNTYYRIELKAHNAIGYSSPASIIM 732
Query 609 TT 610
T
Sbjct 733 KT 734
Score = 44.5 bits (103), Expect = 0.006, Method: Composition-based stats.
Identities = 17/79 (22%), Positives = 30/79 (38%), Gaps = 4/79 (5%)
Query 543 PVDVQNGFIRNYTIFYRTIIGNETAVNVDSS---HTEYTLSSLTSDTLYMVRMAAYTDEG 599
P I Y++ Y+ + + + + S + Y + L T Y R AA G
Sbjct 548 PSTELGLPILAYSVQYKEALNPDWSTAYNRSWSPDSPYIVEGLRPQTEYSFRFAARNQVG 607
Query 600 GKD-GPEFTFTTPKFAQGE 617
+ G +TP+ + E
Sbjct 608 LGNWGVNQQQSTPRRSAPE 626
>sp|Q9IBD8|PTPRC_CYPCA Receptor-type tyrosine-protein phosphatase
C OS=Cyprinus carpio OX=7962 GN=ptprc PE=2 SV=1
Length=1216
Score = 68.0 bits (164), Expect = 4e-10, Method: Composition-based stats.
Identities = 67/453 (15%), Positives = 123/453 (27%), Gaps = 70/453 (15%)
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD-LKPFTEYVFRIRCMKEDGKG 308
Y I+ + K + +IP + T + + + LKP T Y I G+
Sbjct 92 NGSKSQNYTIRIKDKKSE--KKIPVSIVSDTTTIDILFEWLKPCTNYSVNIDNCNVVGEN 149
Query 309 YW------------------------SDWS-EEASGITYED----RPSK----------- 328
++ S W+ + IT ED +P +
Sbjct 150 HFNLNVLKSVNHSAEPKGDEQVCFKDSKWNLTKCVNITTEDSCVQKPIQINLETCNYTMN 209
Query 329 --APSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL---DYEVTLTRWKSHLQNYTVN 383
P +I S + + V W P N ++V T + + V
Sbjct 210 VHMPPVKPEITFSESIPTKFV---WSNKPLSSDNVTSQCKDTFKVKCTDDTEYDLDKDVF 266
Query 384 ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEW 443
+Y T + K V + + + N + + W
Sbjct 267 LKPSEEYTCTGKYKYYNTSIDSKSK---QVNIHCEWINE------TVFSEVTSNSIVIFW 317
Query 444 TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADG 503
K I + ++ + L Y T++
Sbjct 318 NLSPGDKCKGITWEKFSAICKKSHDQKCRKVNDTTAECVFSELKSYINYTCTLSAEVNKS 377
Query 504 PGSPESIKAYLKQAPPSKGP------TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF 557
G Q S P V+ K+ N + L D NG + I+
Sbjct 378 IGVFPIYTRDFNQRTNSSNPSFEDHDNVKVKETSHNSFNVNCKNLKPDEWNGP-KG--IY 434
Query 558 YRTIIGNETAV-NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
++ N V + +T +L T Y + + A + + T +T +
Sbjct 435 IAKLLSNRPPVTKENPKSCSFTFENLYYHTEYTIEIIAINGNKNESSAKATHSTRYNDKA 494
Query 617 EIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKK 649
I +V + + L + KR +
Sbjct 495 LIGFLVFLILVTSLALLFVLYKLFLLKRKRTAE 527
Score = 42.5 bits (98), Expect = 0.021, Method: Composition-based stats.
Identities = 27/173 (16%), Positives = 51/173 (29%), Gaps = 31/173 (18%)
Query 57 YFHVNANYIVWKTNHFTIPKEQY---TIINRTASSVTFTDIASLNIQLTCNILTFGQLEQ 113
I W+ K +N T + F+++ S I TC +
Sbjct 320 SPGDKCKGITWEKFSAICKKSHDQKCRKVNDTTAECVFSELKSY-INYTCTLSAEVNKSI 378
Query 114 NVYGI-------TIISGLPPEKP---KNLSCIVNEGKKMRC------EWDGGRETHLETN 157
V+ I S P + + + + C EW+G + +
Sbjct 379 GVFPIYTRDFNQRTNSSNPSFEDHDNVKVKETSHNSFNVNCKNLKPDEWNGPK--GIYIA 436
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN-IEVWVEAENALGKVTS 209
L + K + P SC+ + +Y+ + + A N +S
Sbjct 437 KLLSNRPPVTK--------ENPKSCSFTFENLYYHTEYTIEIIAINGNKNESS 481
>sp|P50400|GUND_CELFI Endoglucanase D OS=Cellulomonas fimi OX=1708
GN=cenD PE=3 SV=1
Length=747
Score = 67.6 bits (163), Expect = 4e-10, Method: Composition-based stats.
Identities = 32/205 (16%), Positives = 58/205 (28%), Gaps = 21/205 (10%)
Query 402 VRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
V + G S + V T P P + + + W+ ++ + + V
Sbjct 433 VGSTTGTSISQVGGGTPDTTAPTAPTGLRAGTPTASTVPLTWSASTDTGGSGVAGYEVYR 492
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ----- 516
T T +Y LA Y +V G S S +
Sbjct 493 GTTLVGT-------TTATSYTVTGLAADSAYTFSVRAKDGAGNTSAASAAVTARTAAGGG 545
Query 517 --APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH 574
PS + L W D + Y ++ + + +
Sbjct 546 DVTAPSVPTGLTAGTPTATSVPLTWTAS-TDTGGSGVTGYEVY------RGSTLVARPTG 598
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEG 599
T +T++ L++ T Y + A G
Sbjct 599 TSHTVTGLSAATAYTFTVRAVDAAG 623
Score = 64.5 bits (155), Expect = 3e-09, Method: Composition-based stats.
Identities = 40/232 (17%), Positives = 63/232 (27%), Gaps = 27/232 (12%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P P L + W +T + T A T T D
Sbjct 454 PTAPTGLRAGTPTASTVPLTWSASTDTGGSGVAGYEVYRGTTLVGTTTATSYTVTGLAAD 513
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPV------YKVKPNPPHNLSVINSEELSSI 239
+ V A++ G ++ P+ P L+ ++
Sbjct 514 SA------YTFSVRAKDGAGNTSAASAAVTARTAAGGGDVTAPSVPTGLTAGTP--TATS 565
Query 240 LKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ LTWT + + Y + YR T +S TV L T Y F
Sbjct 566 VPLTWTASTDTGGSGVTGYEV-YRG---------STLVARPTGTSHTVTGLSAATAYTFT 615
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
+R + G S S T D + + + Y + V L
Sbjct 616 VRAVDAA--GNVSAASAPVGVTTAPDPTTGSCAVTYTANGWSGGFTAAVTLT 665
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 42/227 (19%), Positives = 75/227 (33%), Gaps = 23/227 (10%)
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
+ G T + AP+ P+ + TV L W +G + YEV R +
Sbjct 443 QVGGGTPDTTAPTAPTGLRAGTPTAS----TVPLTWSASTDTGGSG-VAGYEVY--RGTT 495
Query 376 HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC------DFQATHPVMD 429
+ T + +T + Y ++ ++ G + AA + A D A
Sbjct 496 LVGTTTATSYTVTGLAADSAYTFSVRAKDGAGNTSAASAAVTARTAAGGGDVTAPSVPTG 555
Query 430 LKA-FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAE 488
L A P + + WT ++ + + V T + GT ++ L+
Sbjct 556 LTAGTPTATSVPLTWTASTDTGGSGVTGYEVY----RGSTLVARPTGT---SHTVTGLSA 608
Query 489 SKCYLITVTPVYADGP--GSPESIKAYLKQAPPSKGPTVRTKKVGKN 533
+ Y TV V A G + + P + V G +
Sbjct 609 ATAYTFTVRAVDAAGNVSAASAPVGVTTAPDPTTGSCAVTYTANGWS 655
Score = 38.7 bits (88), Expect = 0.28, Method: Composition-based stats.
Identities = 32/202 (16%), Positives = 52/202 (26%), Gaps = 27/202 (13%)
Query 444 TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL-AESKCYLITVTPVYAD 502
+L+ DW+ D + T L L Y+ V
Sbjct 384 NPNSGDTGGLLLD------------DWKTWDEVKYSTMLEPTLWKHGGKYVGLDHQVPLG 431
Query 503 GPGSP-----ESIKAYLKQA-PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
G GS + P+ +R + L W D + Y +
Sbjct 432 GVGSTTGTSISQVGGGTPDTTAPTAPTGLRAGTPTASTVPLTWSAS-TDTGGSGVAGYEV 490
Query 557 FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG-GKDGPEFTFTTPKFAQ 615
+ T + T + + L +D+ Y + A G
Sbjct 491 YRGTTLVGTTTATSYTV------TGLAADSAYTFSVRAKDGAGNTSAASAAVTARTAAGG 544
Query 616 GEIEAIVVPVCLAFLLTTLLGV 637
G++ A VP L T V
Sbjct 545 GDVTAPSVPTGLTAGTPTATSV 566
>sp|B3N666|IHOG_DROER Interference hedgehog OS=Drosophila erecta
OX=7220 GN=iHog PE=3 SV=1
Length=879
Score = 67.6 bits (163), Expect = 4e-10, Method: Composition-based stats.
Identities = 34/198 (17%), Positives = 64/198 (32%), Gaps = 26/198 (13%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR--- 479
P + D + + W PR ++ + V +WQ + +
Sbjct 461 PPSPPNVTRL--SDESVMLRWMVPRNDGLPIVI-FKVQYRMVGKRKNWQTTNDNIPYGKP 517
Query 480 ----------TYLRGNLAESKCYLITVTPV--YADGPGSPESIKAYLKQAP---PSKGPT 524
T +L Y + V D S S K YL+ P P
Sbjct 518 KWNSELGKSFTASVTDLKPQHTYRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPE 577
Query 525 -VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSH-TEYTLS 580
+ ++ + VL W L D I Y +YR G ++ +H + ++
Sbjct 578 LLEIEEYSETAVVLHWS-LASDADEHLITGYYAYYRPSSSAGEYFKATIEGAHARSFKIA 636
Query 581 SLTSDTLYMVRMAAYTDE 598
L + T+Y ++ +++
Sbjct 637 PLETATMYEFKLQSFSAV 654
Score = 59.1 bits (141), Expect = 2e-07, Method: Composition-based stats.
Identities = 50/275 (18%), Positives = 81/275 (29%), Gaps = 46/275 (17%)
Query 196 VWVEAENALGKVTS-DHINFDP-----------VYKVKPN---------PPHNLSVINSE 234
V A N LG+ ++ + +P ++ KPN PP +V
Sbjct 412 VQCFARNRLGEHSAGTLLQVNPKQIQEPRESGGTHRPKPNQGSKQKQMYPPSPPNVTRLS 471
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS-TWSQIPPEDTAST---------RSSF 284
+ S + L W P + I+ + +QYR W +
Sbjct 472 DES--VMLRWMVPRNDGLPIVIFKVQYRMVGKRKNWQTTNDNIPYGKPKWNSELGKSFTA 529
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR-PSKAPSFWYKIDPSHTQG 343
+V DLKP Y FRI + + S+ S + P P + S T
Sbjct 530 SVTDLKPQHTYRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPELLEIEEYSET-- 587
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN-------ATKLTVNLTNDRY 396
V L W + + I Y S + + + K+ T Y
Sbjct 588 --AVVLHWSLASDADEH-LITGYYAYYRPSSSAGEYFKATIEGAHARSFKIAPLETATMY 644
Query 397 LATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
L + V S+ + L T +
Sbjct 645 EFKLQSFSAVSASEFSALKQGRTQRPKTSTTEEPT 679
>sp|B4LRN7|IHOG_DROVI Interference hedgehog OS=Drosophila virilis
OX=7244 GN=iHog PE=3 SV=1
Length=907
Score = 67.6 bits (163), Expect = 4e-10, Method: Composition-based stats.
Identities = 44/275 (16%), Positives = 83/275 (30%), Gaps = 52/275 (19%)
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGT 476
Q P D + + W R ++ + +++ +L++ WQ +
Sbjct 463 QTQMVPPSAPNVTRLSDESVMLRWHVVRNDGLPIQFFKVQYRMLTESG-KRKSWQTTNEN 521
Query 477 VHRTYLR--------------GNLAESKCYLITVTPV--YADGPGSPESIKAYLKQAP-- 518
+ R L + Y + V D S S K +L++
Sbjct 522 IPYGRQRHESGAGVRNFTSSVTGLKPNSSYRFRIMAVYSNNDNKESNTSGKFFLQRGAAL 581
Query 519 -PSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVD-SS 573
P P V ++ + VL W L D I Y +YR G +D +
Sbjct 582 APLAVPELVDIEEYSQTAVVLHWR-LSSDADEQLISGYYAYYRPSASAGEYLKATIDGAK 640
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDE----------GGKDGPEFT-----------FTTPK 612
+ +S+L T+Y ++ +++ G P + TTP
Sbjct 641 SRSFQISALEPGTIYEFKLQSFSAVAASEFSALKQGRTQRPRASSTPQPVLHAVDTTTPS 700
Query 613 FAQG---EIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
+ A L+ ++ C +R
Sbjct 701 HNETFNMNPMLTGTIGGGALLVLLVISACLCLCRR 735
Score = 52.6 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 43/241 (18%), Positives = 75/241 (31%), Gaps = 28/241 (12%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-----TNFTLKSEWATHKFADCKAKR-- 176
+PP P N++ + +E + W R L + + +E K +
Sbjct 467 VPPSAP-NVTRLSDE--SVMLRWHVVRNDGLPIQFFKVQYRMLTESGKRKSWQTTNENIP 523
Query 177 ----------DTPTSCTVDYSTVYFVNIEVWVEAE--NALGKVTSDHINFDPVYKVKPNP 224
+ + + A N K ++ F P
Sbjct 524 YGRQRHESGAGVRNFTSSVTGLKPNSSYRFRIMAVYSNNDNKESNTSGKFFLQRGAALAP 583
Query 225 PHNLSVINSEELS-SILKLTWTNPSIKSV-IILKYNIQYRTKDASTWSQIPPEDTASTRS 282
+++ EE S + + L W S +I Y YR ++ D A +R
Sbjct 584 LAVPELVDIEEYSQTAVVLHWRLSSDADEQLISGYYAYYRPSASAGEYLKATIDGAKSR- 642
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
SF + L+P T Y F+++ S++S G T R S P + T
Sbjct 643 SFQISALEPGTIYEFKLQSFSAVAA---SEFSALKQGRTQRPRASSTPQPVLHAVDTTTP 699
Query 343 G 343
Sbjct 700 S 700
>sp|B4NZY8|IHOG_DROYA Interference hedgehog OS=Drosophila yakuba
OX=7245 GN=iHog PE=3 SV=1
Length=880
Score = 67.6 bits (163), Expect = 4e-10, Method: Composition-based stats.
Identities = 34/198 (17%), Positives = 64/198 (32%), Gaps = 26/198 (13%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR--- 479
P + D + + W PR ++ + V +WQ + +
Sbjct 461 PPTPPNVTRL--SDESVMLRWMVPRNDGLPIVI-FKVQYRMVGKRKNWQTTNDNIPYGKP 517
Query 480 ----------TYLRGNLAESKCYLITVTPV--YADGPGSPESIKAYLKQAP---PSKGPT 524
T +L Y + V D S S K YL+ P P
Sbjct 518 KWNSELGKSFTASVTDLKPQHTYRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPE 577
Query 525 -VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSH-TEYTLS 580
+ ++ + VL W L D I Y +YR G ++ +H + ++
Sbjct 578 LLEIEEYSETAVVLHWS-LASDADEHLITGYYAYYRPSSSAGEYFKATIEGAHARSFKIA 636
Query 581 SLTSDTLYMVRMAAYTDE 598
L + T+Y ++ +++
Sbjct 637 PLETATMYEFKLQSFSAV 654
Score = 63.3 bits (152), Expect = 8e-09, Method: Composition-based stats.
Identities = 72/477 (15%), Positives = 134/477 (28%), Gaps = 77/477 (16%)
Query 5 QTWLVQALFIFLTTESTGELLDP---CGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVN 61
+ L +L + +T E + P G + + ++ S+ +C
Sbjct 230 RIQLTGSLQLQVTPEQRSQSKSPHLLNGQPNSQEITIREGSSLLLLC-------PGVGSP 282
Query 62 ANYIVWKTNHF--TIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGIT 119
+VW + + ++ +I +I++ +Q + F
Sbjct 283 PPTVVWSSPDVVGAVKNKRSKVIGHA------LEISNTRVQDAGTYICFQDNGVRPVLEH 336
Query 120 IISGLPPEKPKNLSCIVNEGKK------MRCEWDGGRETHLETNFTLKSEWATHKFADCK 173
I + P+ + + + CE T + T + H D
Sbjct 337 YIKVHVEQPPQIVRPPWADLTNEGDRLKLECE-----ATGVPT-PEIYWLLNGHSSLDDT 390
Query 174 AKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS-DHINFDP-----------VYKVK 221
+ + V A N LG+ ++ + +P ++ K
Sbjct 391 EAELSNNFLILHSVLKRHAGY-VQCFARNRLGEHSAGTLLQVNPKQIQEPRESGGTHRPK 449
Query 222 PN---------PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS-TWSQ 271
PN PP +V + S + L W P + I+ + +QYR W
Sbjct 450 PNQGSKQKQMYPPTPPNVTRLSDES--VMLRWMVPRNDGLPIVIFKVQYRMVGKRKNWQT 507
Query 272 IPPEDTAST---------RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ +V DLKP Y FRI + + S+ S +
Sbjct 508 TNDNIPYGKPKWNSELGKSFTASVTDLKPQHTYRFRILAVYSNNDNKESNTSAKFYLQPG 567
Query 323 EDR-PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYT 381
P P + S T V L W + + I Y S + +
Sbjct 568 AALDPMPVPELLEIEEYSET----AVVLHWSLASDADEH-LITGYYAYYRPSSSAGEYFK 622
Query 382 VN-------ATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
+ K+ T Y L + V S+ + L T +
Sbjct 623 ATIEGAHARSFKIAPLETATMYEFKLQSFSAVSASEFSALKQGRTQRPKTSTTEEPT 679
>sp|O15034|RIMB2_HUMAN RIMS-binding protein 2 OS=Homo sapiens
OX=9606 GN=RIMBP2 PE=1 SV=3
Length=1052
Score = 67.6 bits (163), Expect = 4e-10, Method: Composition-based stats.
Identities = 39/304 (13%), Positives = 99/304 (33%), Gaps = 36/304 (12%)
Query 129 PKNLSCIVNEGKKMRCEWDGGRET---HLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P+ ++ I K + W+ +++ + + T ++ ++
Sbjct 300 PRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKAL----IE 355
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ + V+ + G V P +L V N ++S+ +L+W
Sbjct 356 KLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVV-APSHLRVDNITQISA--QLSW- 411
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
P+ + + + ++ + + R + +L+P Y ++
Sbjct 412 LPTNSNYSHVIFL-----------NEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQ 460
Query 306 GKGYWSDWSEEAS----GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTL---PPFE 358
W E+ + + P+ P+ + T+++ W+ P
Sbjct 461 M--PWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGL 518
Query 359 ANG-KILDYEVTLTRWKSHLQNYTVNAT---KLTVNLTNDRYLATLTVRNLVGKS-DAAV 413
+NG + Y V + + + +L + + T+ + G+S D+AV
Sbjct 519 SNGANVTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAV 578
Query 414 LTIP 417
+P
Sbjct 579 AAVP 582
Score = 64.1 bits (154), Expect = 5e-09, Method: Composition-based stats.
Identities = 43/275 (16%), Positives = 78/275 (28%), Gaps = 28/275 (10%)
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLT 401
Q ++V + W+ G + Y V + + L L ++
Sbjct 308 QLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMAACTYRIS 367
Query 402 V--RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCV 459
V G SD T+ P + W P S +++
Sbjct 368 VQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSW-LPTNSNYSHVI---F 423
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA-- 517
L+++ I + Y NL + Y + V P + K+A
Sbjct 424 LNEEEFDIVKAAR------YKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFV 477
Query 518 --------PPSKGPTVRTKK-VGKNEAVLEWDQL---PVDVQNG-FIRNYTIFYRTIIGN 564
PP+ V + V + W P + NG + Y ++ +
Sbjct 478 EFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVA 537
Query 565 ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
E + + T L L S V + + +G
Sbjct 538 EV-IFPTADSTAVELVRLRSLEAKGVTVRTLSAQG 571
Score = 49.5 bits (116), Expect = 2e-04, Method: Composition-based stats.
Identities = 35/192 (18%), Positives = 63/192 (33%), Gaps = 16/192 (8%)
Query 404 NLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK-KYILEWCVLSD 462
N G D + I + +K K + V W P + + VL D
Sbjct 280 NSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKS--VIVGWEPPAVPPGWGTVSSYNVLVD 337
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
K T G+ + + + Y I+V V + G + +
Sbjct 338 KE---TRMNLTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAP 394
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL 582
+R + + A L W LP + + IF + E + V ++ +Y +L
Sbjct 395 SHLRVDNITQISAQLSW--LPTNSNYSHV----IF---LNEEEFDI-VKAARYKYQFFNL 444
Query 583 TSDTLYMVRMAA 594
+ Y V++ A
Sbjct 445 RPNMAYKVKVLA 456
Score = 48.3 bits (113), Expect = 4e-04, Method: Composition-based stats.
Identities = 40/336 (12%), Positives = 94/336 (28%), Gaps = 47/336 (14%)
Query 203 ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS--VIILKYNIQ 260
+ ++ ++ + + P+ + ++L+ + + W P++ + YN+
Sbjct 276 GITDNSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNV- 334
Query 261 YRTKDASTWSQIPPEDTASTRSSFTVQDLK-PFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
D T + T +R+ ++ L Y ++C+ G S+E
Sbjct 335 --LVDKETRMNL----TLGSRTKALIEKLNMAACTYRISVQCVTSRGS------SDELQC 382
Query 320 ITYEDRP-SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
+ APS + + + QL W + + L + +
Sbjct 383 TLLVGKDVVVAPSHLRVDNITQI----SAQLSWLPTNSN------YSHVIFLNEEEFDIV 432
Query 379 NYTVNATKLTVNLTNDRYLATLTVRN---------LVGKSDAAVLTIPACDFQATHPVMD 429
+ N Y + + + A + P D
Sbjct 433 KAARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQD 492
Query 430 LKAFPKDN--MLWVEWTTPRESVKKY-----ILEWCVLSDKAPCITDWQQEDGTVHRTYL 482
+ + V W P + + + V + + T T +
Sbjct 493 VTVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVA---EVIFPTADSTAV 549
Query 483 R-GNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
L + +TV + A G ++ A +
Sbjct 550 ELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPPEL 585
Score = 39.8 bits (91), Expect = 0.14, Method: Composition-based stats.
Identities = 16/108 (15%), Positives = 37/108 (34%), Gaps = 6/108 (6%)
Query 497 TPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
+ + G+ + + + + K ++ W+ V G + +Y +
Sbjct 275 AGITDNSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNV 334
Query 557 FYRTIIGNETAVNVD-SSHTEYTLSSLTSDT-LYMVRMAAYTDEGGKD 602
++ ET +N+ S T+ + L Y + + T G D
Sbjct 335 ----LVDKETRMNLTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSD 378
>sp|B4Q599|IHOG_DROSI Interference hedgehog OS=Drosophila simulans
OX=7240 GN=iHog PE=3 SV=2
Length=880
Score = 67.2 bits (162), Expect = 5e-10, Method: Composition-based stats.
Identities = 34/198 (17%), Positives = 64/198 (32%), Gaps = 26/198 (13%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR--- 479
P + D + + W PR ++ + V +WQ + +
Sbjct 461 PPTPPNVTRL--TDESVMLRWMVPRNDGLPIVI-FKVQYRMVGKRKNWQTTNDNIPYGKP 517
Query 480 ----------TYLRGNLAESKCYLITVTPV--YADGPGSPESIKAYLKQAP---PSKGPT 524
T +L Y + V D S S K YL+ P P
Sbjct 518 KWNSELGKSFTASVTDLKPEHTYRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPE 577
Query 525 -VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSH-TEYTLS 580
+ ++ + VL W L D I Y +YR G ++ +H + ++
Sbjct 578 LLEIEEYSETAVVLHWS-LASDADEHLITGYYAYYRPSSSAGEYFKATIEGAHARSFKIA 636
Query 581 SLTSDTLYMVRMAAYTDE 598
L + T+Y ++ +++
Sbjct 637 PLETATMYEFKLQSFSAV 654
Score = 60.3 bits (144), Expect = 7e-08, Method: Composition-based stats.
Identities = 41/226 (18%), Positives = 65/226 (29%), Gaps = 25/226 (11%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS-TWSQIPPEDTAST-- 280
PP +V + S + L W P + I+ + +QYR W
Sbjct 461 PPTPPNVTRLTDES--VMLRWMVPRNDGLPIVIFKVQYRMVGKRKNWQTTNDNIPYGKPK 518
Query 281 -------RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR-PSKAPSF 332
+ +V DLKP Y FRI + + S+ S + P P
Sbjct 519 WNSELGKSFTASVTDLKPEHTYRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPEL 578
Query 333 WYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN-------AT 385
+ S T V L W + + I Y S + + +
Sbjct 579 LEIEEYSET----AVVLHWSLASDADEH-LITGYYAYYRPSSSAGEYFKATIEGAHARSF 633
Query 386 KLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
K+ T Y L + V S+ + L T +
Sbjct 634 KIAPLETATMYEFKLQSFSAVSASEFSALKQGRTQRPKTSTTEEPT 679
>sp|P20533|CHIA1_NIACI Chitinase A1 OS=Niallia circulans OX=1397
GN=chiA1 PE=1 SV=1
Length=699
Score = 66.8 bits (161), Expect = 6e-10, Method: Composition-based stats.
Identities = 35/222 (16%), Positives = 64/222 (29%), Gaps = 27/222 (12%)
Query 404 NLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWTTPRESVKKYILEWCVLSD 462
N + T+P D A + ++ N + + W ++V + + V +
Sbjct 445 NKLKADLPTGGTVPPVDTTAPSVPGNARSTGVTANSVTLAWNASTDNVG--VTGYNVYNG 502
Query 463 KAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPES----IKAYLKQA- 517
T L Y T+ A G S S + +
Sbjct 503 ANLA-------TSVTGTTATISGLTAGTSYTFTIKAKDAAGNLSAASNAVTVSTTAQPGG 555
Query 518 ---PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH 574
P+ + + + L W N + Y ++ N TA+ +
Sbjct 556 DTQAPTAPTNLASTAQTTSSITLSWT---ASTDNVGVTGYDVY------NGTALATTVTG 606
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
T T+S L +DT Y + A G + A+
Sbjct 607 TTATISGLAADTSYTFTVKAKDAAGNVSAASNAVSVKTAAET 648
Score = 62.6 bits (150), Expect = 1e-08, Method: Composition-based stats.
Identities = 36/225 (16%), Positives = 75/225 (33%), Gaps = 31/225 (14%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P P N + W+ + T + + + A S
Sbjct 465 PSVPGNARSTGVTANSVTLAWNASTDNVGVTGYNV---YNGANLATSVTGTTATIS---- 517
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN-------PPHNLSVINSEELSS 238
+ ++A++A G +++ +P P NL+ ++ + +S
Sbjct 518 -GLTAGTSYTFTIKAKDAAGNLSAASNAVTVSTTAQPGGDTQAPTAPTNLA--STAQTTS 574
Query 239 ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ L+WT + +V + Y++ T T ++ T+ L T Y F
Sbjct 575 SITLSWTASTD-NVGVTGYDV----------YNGTALATTVTGTTATISGLAADTSYTFT 623
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQG 343
++ G S S S T + + S W +++ ++T G
Sbjct 624 VKAKDAA--GNVSAASNAVSVKTAAETTNPGVSAW-QVNTAYTAG 665
Score = 59.1 bits (141), Expect = 2e-07, Method: Composition-based stats.
Identities = 41/221 (19%), Positives = 67/221 (30%), Gaps = 23/221 (10%)
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHL 377
+G T + APS + +V L W N + Y V +
Sbjct 453 TGGTVPPVDTTAPSVPGNARSTGVTAN-SVTLAWNA---STDNVGVTGYNVY--NGANLA 506
Query 378 QNYTVNATKLTVNLTNDRYLATLTVRNLVG-------KSDAAVLTIPACDFQATHPVMDL 430
+ T ++ Y T+ ++ G + P D QA +L
Sbjct 507 TSVTGTTATISGLTAGTSYTFTIKAKDAAGNLSAASNAVTVSTTAQPGGDTQAPTAPTNL 566
Query 431 KAFP-KDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES 489
+ + + + WT ++V + + V + A T T LA
Sbjct 567 ASTAQTTSSITLSWTASTDNVG--VTGYDVYNGTALATT-------VTGTTATISGLAAD 617
Query 490 KCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKV 530
Y TV A G S S +K A + P V +V
Sbjct 618 TSYTFTVKAKDAAGNVSAASNAVSVKTAAETTNPGVSAWQV 658
>sp|Q38J84|IL2RB_PANTR Interleukin-2 receptor subunit beta OS=Pan
troglodytes OX=9598 GN=IL2RB PE=2 SV=1
Length=551
Score = 66.8 bits (161), Expect = 6e-10, Method: Composition-based stats.
Identities = 37/214 (17%), Positives = 69/214 (32%), Gaps = 16/214 (7%)
Query 132 LSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAK----RDTPTSC----- 182
+C N + C W ++ L+ W + + + +C
Sbjct 34 FTCFYNSRANISCVWS--QDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILG 91
Query 183 TVDYSTVYFVNI-EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
D + V+I + V + +F P ++ P +L V++ E +
Sbjct 92 APDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVE--THRCN 149
Query 242 LTWTNPSIKSVIILKYNIQYRTKD-ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
++W + RT TW + P + ++ L P T+Y F++R
Sbjct 150 ISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVR 209
Query 301 CMKEDG-KGYWSDWSEEASGITYEDRPSKAPSFW 333
G WS WS+ + T K W
Sbjct 210 VKPLQGEFTTWSPWSQPLAFRTKPASLGKDTIPW 243
Score = 38.7 bits (88), Expect = 0.27, Method: Composition-based stats.
Identities = 39/228 (17%), Positives = 71/228 (31%), Gaps = 34/228 (15%)
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNET-----AVNVDSSHT 575
+++ V + + W+ F R+ RT+ T + +
Sbjct 134 APISLQVVHVETHRCNISWEISQASHY--FERHLEFEARTLSPGHTWEEAPLLTLKQKQE 191
Query 576 EYTLSSLTSDTLYMVRMAAYTDEG--GKDGPEFT---FTTPKFAQGE-------IEAIVV 623
L +LT DT Y ++ +G P F T + G+ + +
Sbjct 192 WICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPASLGKDTIPWLGHLLVGL 251
Query 624 PVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK-----SH-----IAQWSPHTPPR 673
F++ L ++ C N +KK + + PDPSK S + +W P
Sbjct 252 SGAFGFIILVYL-LINCRNTGPWLKKVLKCHTPDPSKFFSQLSSEHGGDVQKWLSSPFPS 310
Query 674 HNFNSKDQMYSDGNFTDVSVVE----IEANDKKPFPEDLKSLDLFKKE 717
+F+ + + + DK P P L S
Sbjct 311 SSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSC 358
>sp|Q29JX6|IHOG_DROPS Interference hedgehog OS=Drosophila pseudoobscura
pseudoobscura OX=46245 GN=iHog PE=3 SV=1
Length=903
Score = 66.4 bits (160), Expect = 1e-09, Method: Composition-based stats.
Identities = 35/220 (16%), Positives = 75/220 (34%), Gaps = 35/220 (16%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
P + D + + W PR + + +++ ++S+ +WQ + +
Sbjct 470 PPSPPNVTRL--SDESVMLRWHVPRNDGLLILFFKVQYRMISEGKR--KNWQTTNDNIPY 525
Query 480 -------------TYLRGNLAESKCYLITVTPV--YADGPGSPESIKAYLKQAPPSKGPT 524
T +L + Y + V D S S K YL+ +
Sbjct 526 GKPKWNSELGKSFTASVTDLKPQRTYRFRILAVYSNNDNKESNTSAKFYLQPGAALEPMP 585
Query 525 V----RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSH-TEY 577
V ++ + VL W L D I Y +YR G ++ +H +
Sbjct 586 VPELLEIEEYSETAVVLHWR-LDSDADEHLITGYYAYYRPSSSAGEYYKATIEGAHARSF 644
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
+++L + T+Y ++ +++ F+ K + +
Sbjct 645 QIATLEAATIYEFKLQSFSAV-----SASEFSALKQGRTQ 679
Score = 64.5 bits (155), Expect = 4e-09, Method: Composition-based stats.
Identities = 43/243 (18%), Positives = 72/243 (30%), Gaps = 30/243 (12%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS---TWSQI 272
P + P+PP N++ ++ E + L W P ++IL + +QYR W
Sbjct 465 PTKMIPPSPP-NVTRLSDE----SVMLRWHVPRNDGLLILFFKVQYRMISEGKRKNWQTT 519
Query 273 PPEDTAST---------RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+ +V DLKP Y FRI + + S+ S +
Sbjct 520 NDNIPYGKPKWNSELGKSFTASVTDLKPQRTYRFRILAVYSNNDNKESNTSAKFYLQPGA 579
Query 324 D-RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY-- 380
P P + S T V L W+ + + I Y S + Y
Sbjct 580 ALEPMPVPELLEIEEYSET----AVVLHWRLDSDADEH-LITGYYAYYRPSSSAGEYYKA 634
Query 381 ---TVNATKLTVNLTNDR--YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK 435
+A + Y L + V S+ + L +
Sbjct 635 TIEGAHARSFQIATLEAATIYEFKLQSFSAVSASEFSALKQGRTQRPKASTTEEPTIQGI 694
Query 436 DNM 438
+
Sbjct 695 GDR 697
>sp|B4GKZ8|IHOG_DROPE Interference hedgehog OS=Drosophila persimilis
OX=7234 GN=iHog PE=3 SV=1
Length=906
Score = 66.0 bits (159), Expect = 1e-09, Method: Composition-based stats.
Identities = 35/220 (16%), Positives = 75/220 (34%), Gaps = 35/220 (16%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRES---VKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
P + D + + W PR + + +++ ++S+ +WQ + +
Sbjct 470 PPSPPNVTRL--SDESVMLRWHVPRNDGLLILFFKVQYRMISEGKR--KNWQTTNDNIPY 525
Query 480 -------------TYLRGNLAESKCYLITVTPV--YADGPGSPESIKAYLKQAPPSKGPT 524
T +L + Y + V D S S K YL+ +
Sbjct 526 GKPKWNSELGKSFTASVTDLKPQRTYRFRILAVYSNNDNKESNTSAKFYLQPGAALEPMP 585
Query 525 V----RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSH-TEY 577
V ++ + VL W L D I Y +YR G ++ +H +
Sbjct 586 VPELLEIEEYSETAVVLHWR-LDSDADEHLITGYYAYYRPSSSAGEYYKATIEGAHARSF 644
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
+++L + T+Y ++ +++ F+ K + +
Sbjct 645 QIATLEAATIYEFKLQSFSAV-----SASEFSALKQGRTQ 679
Score = 64.1 bits (154), Expect = 5e-09, Method: Composition-based stats.
Identities = 43/243 (18%), Positives = 72/243 (30%), Gaps = 30/243 (12%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS---TWSQI 272
P + P+PP N++ ++ E + L W P ++IL + +QYR W
Sbjct 465 PTKMIPPSPP-NVTRLSDE----SVMLRWHVPRNDGLLILFFKVQYRMISEGKRKNWQTT 519
Query 273 PPEDTAST---------RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE 323
+ +V DLKP Y FRI + + S+ S +
Sbjct 520 NDNIPYGKPKWNSELGKSFTASVTDLKPQRTYRFRILAVYSNNDNKESNTSAKFYLQPGA 579
Query 324 D-RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY-- 380
P P + S T V L W+ + + I Y S + Y
Sbjct 580 ALEPMPVPELLEIEEYSET----AVVLHWRLDSDADEH-LITGYYAYYRPSSSAGEYYKA 634
Query 381 ---TVNATKLTVNLTNDR--YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK 435
+A + Y L + V S+ + L +
Sbjct 635 TIEGAHARSFQIATLEAATIYEFKLQSFSAVSASEFSALKQGRTQRPRASTTEEPTIQGI 694
Query 436 DNM 438
+
Sbjct 695 GDR 697
>sp|Q8CII9|CRLF2_MOUSE Cytokine receptor-like factor 2 OS=Mus
musculus OX=10090 GN=Crlf2 PE=1 SV=2
Length=359
Score = 64.5 bits (155), Expect = 2e-09, Method: Composition-based stats.
Identities = 34/198 (17%), Positives = 70/198 (35%), Gaps = 23/198 (12%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCK----AKRDTPTSCTVD 185
+++ + ++ + + W G + H N +L+ + T C + + C +
Sbjct 27 GDVTVVCHDLETVEVTWGSGPDHHGA-NLSLEFRYGTGALQPCPRYFLSGAGVTSGCILP 85
Query 186 YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+ + + + G +KP PP N++++ + + + ++W
Sbjct 86 AARAGLLELALR-----DGGGAMVFKARQRASAWLKPRPPWNVTLLWTPDGD--VTVSWP 138
Query 246 NPSIKSVIILKYNIQYRTK--DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
S + L Y +Q+R D W T+ TV L P Y FR+R
Sbjct 139 AHS---YLGLDYEVQHRESNDDEDAWQT-----TSGPCCDLTVGGLDPARCYDFRVRASP 190
Query 304 E-DGKGYWSDWSEEASGI 320
G + SE +
Sbjct 191 RAAHYGLEAQPSEWTAVT 208
Score = 45.6 bits (106), Expect = 0.001, Method: Composition-based stats.
Identities = 43/248 (17%), Positives = 67/248 (27%), Gaps = 30/248 (12%)
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA-VNVDS 572
P V + + W P G +Y + +R +E A
Sbjct 112 SAWLKPRPPWNVTLLWTPDGDVTVSW---PAHSYLG--LDYEVQHRESNDDEDAWQTTSG 166
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEG-----GKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
+ T+ L Y R+ A + T A P
Sbjct 167 PCCDLTVGGLDPARCYDFRVRASPRAAHYGLEAQPSEWTAVTRLSGAASAASCTASPAPS 226
Query 628 AFLLTTLLGVLFC------------FNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHN 675
L LL + + +K + P VPDPS S + H
Sbjct 227 PALAPPLLPLGCGLAALLTLSLLLAALRLRRVKDALLPCVPDPSGSFPGLFEKHHGNFQA 286
Query 676 FNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSL------DLFKKEKINTEGHSSGIG 729
+ + Q + T+ I K+ PED SL F+ G +G
Sbjct 287 WIADAQATAPPARTEEEDDLIHPKAKRVEPEDGTSLCTVPRPPSFEPRG-PGGGAMVSVG 345
Query 730 GSSCMSSS 737
G++ M
Sbjct 346 GATFMVGD 353
>sp|Q00941|CSF2R_MOUSE Granulocyte-macrophage colony-stimulating
factor receptor subunit alpha OS=Mus musculus OX=10090 GN=Csf2ra
PE=2 SV=2
Length=388
Score = 64.5 bits (155), Expect = 2e-09, Method: Composition-based stats.
Identities = 40/259 (15%), Positives = 91/259 (35%), Gaps = 17/259 (7%)
Query 79 YTIINRTASSVTFTDIASLNIQLTCNIL-TFGQLEQNVYGITIISGLPPEKPKNLSCIVN 137
+ ++ F + +L+ +T ++ T G + + G +NL+C +
Sbjct 79 HRRVSPFGCRCWFRRMMALHHGVTLDVNGTVGGAAAHWRLSFVNEGAAGSGAENLTCEIR 138
Query 138 EGKKMRCEWDGGRETHLETNFTLKSEWAT-HKFADCKAKRDTP--TSCTVDYSTVYFVNI 194
+ + C W G + ++L+ +T H A C A T C + ++
Sbjct 139 AARFLSCAWREGPAAPADVRYSLRVLNSTGHDVARCMADPGDDVITQCIANDLSLLGSEA 198
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
+ V + G V + PP +++ SS ++W PS + +
Sbjct 199 YLVVTGRSGAGPVRFLDDVVATKALERLGPPRDVTASC---NSSHCTVSWAPPSTWASLT 255
Query 255 ---LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
++ +Q+++ + + P + + P + ++R K +W
Sbjct 256 ARDFQFEVQWQSAEPGS---TPRKVLVVEETRLAFPSPAPHGGHKVKVRAGDTRMK-HWG 311
Query 312 DWSEEASGITYEDRPSKAP 330
+WS E ++ P
Sbjct 312 EWSP---AHPLEAEDTRVP 327
>sp|P13368|7LESS_DROME Protein sevenless OS=Drosophila melanogaster
OX=7227 GN=sev PE=1 SV=2
Length=2554
Score = 66.0 bits (159), Expect = 2e-09, Method: Composition-based stats.
Identities = 67/444 (15%), Positives = 125/444 (28%), Gaps = 80/444 (18%)
Query 263 TKDASTWSQIPPED--TASTRSSFTVQDLKPFTEYVFR--IRCMKEDGKGYWSDWSEEAS 318
+ P S + DL PFT Y + + +
Sbjct 1732 PGSEEHDHGVEPLGQWLLGAGESLNLTDLLPFTRYRVSGILSSFYQKKLALPTLVLAPLE 1791
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL-------- 370
+T PS +F ++ R +++ W LPP + + + Y +
Sbjct 1792 LLTASATPSPPRNFSVRV-----LSPRELEVSW--LPPEQLRSESVYYTLHWQQELDGEN 1844
Query 371 ----TRWKSHLQNY-TVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATH 425
W++H + T +LT Y + KS+++
Sbjct 1845 VQDRREWEAHERRLETAGTHRLTGIKPGSGYSLWVQAHATPTKSNSSERLHVRSF---AE 1901
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGN 485
L + W + + LE +++ + H +
Sbjct 1902 LPELQLLELGPYSLSLTWAGTPDPLGSLQLECRSSAEQLR------RNVAGNHTKMVVEP 1955
Query 486 LAESKCYLITVTPVYADGPGSP-----ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
L Y + YA PG+P + L PS+ + + + + + W
Sbjct 1956 LQPRTRYQCRLLLGYAATPGAPLYHGTAEVYETLG-DAPSQPGKPQLEHIAEEVFRVTWT 2014
Query 541 QLPVDVQNG-FIRNYTIFYRTIIGN----------------------ETAVNV------- 570
NG I Y + + E V V
Sbjct 2015 ---AARGNGAPIALYNLEALQARSDIRRRRRRRRRNSGGSLEQLPWAEEPVVVEDQWLDF 2071
Query 571 -DSSHTEYTLSSLTSDTLYMVRMAAYTDE-GGKDGPEFT------FTTPKFAQGEIEAIV 622
+++ + SL S L + R+ A + E G E + F +P+ + AI+
Sbjct 2072 CNTTELSCIVKSLHSSRLLLFRVRARSLEHGWGPYSEESERVAEPFVSPEKRGSLVLAII 2131
Query 623 VPVCLAFLLTTLLGVLFCFNKRDL 646
P + L ++ KR L
Sbjct 2132 APAAIVSSCVLALVLVRKVQKRRL 2155
Score = 57.6 bits (137), Expect = 5e-07, Method: Composition-based stats.
Identities = 44/292 (15%), Positives = 92/292 (32%), Gaps = 39/292 (13%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILK-YNIQYR--------------------T 263
P ++ S+ L + W + + + +NIQY+
Sbjct 314 PQLERAPRADGQSTPLTIRWAMHFPEHYLASRPFNIQYQFVDHHGEELDLEQEDQDASGE 373
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR--IRCMKEDGKGYWSDWSEEASGIT 321
+S W + D ++ L P+T+Y FR + + + +S + A
Sbjct 374 TGSSAWFNLADYDCDEYYVCEILEALIPYTQYRFRFELPFGENRDEVLYSPAT-PAYQTP 432
Query 322 YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN-- 379
E P AP + + + + + W P NG I Y + L+ + + +
Sbjct 433 PEGAPISAPVIEHLMGLDDSH----LAVHWH--PGRFTNGPIEGYRLRLSSSEGNATSEQ 486
Query 380 ---YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK-AFPK 435
+ + Y L++ N G+ A + + P DL +
Sbjct 487 LVPAGRGSYIFSQLQAGTNYTLALSMINKQGEGPVAKGFVQTHSARNEKPAKDLTESVLL 546
Query 436 DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLA 487
V W + + + ++ S + W + + + + G L
Sbjct 547 VGRRAVMWQSLEPAGENSMIY---QSQEELADIAWSKREQQLWLLNVHGELR 595
Score = 55.2 bits (131), Expect = 3e-06, Method: Composition-based stats.
Identities = 21/136 (15%), Positives = 37/136 (27%), Gaps = 9/136 (7%)
Query 482 LRGNLAESKCYLITVTPVYADG-----PGSPESIKAYLKQAPPSKGPTVRTKKVGKNE-A 535
+ L Y + + + P P + +
Sbjct 395 ILEALIPYTQYRFRFELPFGENRDEVLYSPATPAYQTPPEGAPISAPVIEHLMGLDDSHL 454
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNET-AVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
+ W P NG I Y + + GN T V + Y S L + T Y + ++
Sbjct 455 AVHWH--PGRFTNGPIEGYRLRLSSSEGNATSEQLVPAGRGSYIFSQLQAGTNYTLALSM 512
Query 595 YTDEGGKDGPEFTFTT 610
+G + T
Sbjct 513 INKQGEGPVAKGFVQT 528
Score = 54.1 bits (128), Expect = 7e-06, Method: Composition-based stats.
Identities = 51/295 (17%), Positives = 98/295 (33%), Gaps = 52/295 (18%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA-STWSQIPPEDTASTRSS 283
PH+L + + + K++W P Y++ DA +WS +++S+
Sbjct 828 PHSLKALLGAQAA---KISWKEPERNP---------YQSADAARSWSYELEVLDVASQSA 875
Query 284 FTVQD----------LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
F++++ L+P Y R+R + D G +W+E + T+ P +
Sbjct 876 FSIRNIRGPIFGLQRLQPDNLYQLRVRAINVD--GEPGEWTEPLAARTWPLGPHRLRWAS 933
Query 334 YKIDPSHTQGYRT-VQLVWK-----TLPPFEANGKILDY----------EVTLTRWKSHL 377
+ HT +++ + P N + Y + ++W +
Sbjct 934 RQGSVIHTNELGEGLEVQQEQLERLPGPMTMVNESVGYYVTGDGLLHCINLVHSQWGCPI 993
Query 378 QNYTVNATKLTVNLTNDRYLATLTVRNLVG-----KSDAAVLTIPACDFQATHPVMDLKA 432
+ +T + R T RN V +L + +F A P
Sbjct 994 SEPLQHVGSVTYDWRGGRVYWTDLARNCVVRMDPWSGSRELLPVFEANFLALDPRQGHLY 1053
Query 433 FPKDNMLWVEWTTPRESVKKYILEWCVLS------DKAPCITDWQQEDGTVHRTY 481
+ + L +TP E+V Y + S D W + R Y
Sbjct 1054 YATSSQLSRHGSTPDEAVTYYRVNGLEGSIASFVLDTQQDQLFWLVKGSGALRLY 1108
Score = 51.0 bits (120), Expect = 6e-05, Method: Composition-based stats.
Identities = 33/191 (17%), Positives = 58/191 (30%), Gaps = 19/191 (10%)
Query 416 IPACDFQATHPVMDLKAFPKDNMLW----VEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
+P D + + D+ W V W P S + + + +L + +
Sbjct 1189 LPPRDEGVIPMTVLPDSVRLDDGHWDDFHVRWQ-PSTSGGNHSVSYRLLLEFGQRLQTLD 1247
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT---- 527
T L I++TP A G ++ PS+ +R
Sbjct 1248 LSTPFARLTQLP---QAQLQLKISITPRTAWRSGDTTRVQLTTPPVAPSQPRRLRVFVER 1304
Query 528 ----KKVGKNEAVLEWDQLPVDVQNGFIR--NYTIFYRTIIGNETAVNVDSSHTEYTLSS 581
+ AVL WD P Q ++ Y I + ++ S E +
Sbjct 1305 LATALQEANVSAVLRWDA-PEQGQEAPMQALEYHISCWVGSELHEELRLNQSALEARVEH 1363
Query 582 LTSDTLYMVRM 592
L D Y ++
Sbjct 1364 LQPDQTYHFQV 1374
Score = 49.5 bits (116), Expect = 2e-04, Method: Composition-based stats.
Identities = 31/197 (16%), Positives = 60/197 (30%), Gaps = 20/197 (10%)
Query 177 DTPTSCTVDYSTVYFVNIEVWVE---AENALGKVTSDHINFDPVYKVKPN--PPHNLSVI 231
D C + + + + E EN + S P Y+ P P +
Sbjct 388 DEYYVCEILEALIPYTQYRFRFELPFGENRDEVLYSPAT---PAYQTPPEGAPISAPVIE 444
Query 232 NSEELSSI-LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ L L + W + I Y ++ + + + + + R S+ L+
Sbjct 445 HLMGLDDSHLAVHWHPGRFTNGPIEGYRLRLSSSEG---NATSEQLVPAGRGSYIFSQLQ 501
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
T Y + + + G+G + + E + G R V
Sbjct 502 AGTNYTLALSMINKQGEGPVAKGFVQTHSARNEKPAKDLTESVLLV------GRRAVM-- 553
Query 351 WKTLPPFEANGKILDYE 367
W++L P N I +
Sbjct 554 WQSLEPAGENSMIYQSQ 570
Score = 48.3 bits (113), Expect = 4e-04, Method: Composition-based stats.
Identities = 21/166 (13%), Positives = 47/166 (28%), Gaps = 15/166 (9%)
Query 142 MRCEWDGGRETH-LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
W ++ L E+ + + + + +++ +
Sbjct 1216 FHVRWQPSTSGGNHSVSYRLLLEF-GQRLQTLDLSTPFARLTQLPQAQL---QLKISITP 1271
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK-------LTWTNPSIKSVI 253
A + + V P+ P L V E L++ L+ L W P
Sbjct 1272 RTAWRSGDTTRVQL-TTPPVAPSQPRRLRV-FVERLATALQEANVSAVLRWDAPEQGQEA 1329
Query 254 ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
++ ++Y + V+ L+P Y F++
Sbjct 1330 PMQ-ALEYHISCWVGSELHEELRLNQSALEARVEHLQPDQTYHFQV 1374
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 20/146 (14%), Positives = 36/146 (25%), Gaps = 7/146 (5%)
Query 412 AVLTIPACDFQATHPVMDLKAFPK-----DNMLWVEWTTPRESVKKYILEWCVLSDKAPC 466
PA + D+ L V W P I + + +
Sbjct 422 YSPATPAYQTPPEGAPISAPVIEHLMGLDDSHLAVHW-HPGRFTNGPIEGYRLRLSSSEG 480
Query 467 ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-TV 525
+Q +Y+ L Y + ++ + G G A K +
Sbjct 481 NATSEQLVPAGRGSYIFSQLQAGTNYTLALSMINKQGEGPVAKGFVQTHSARNEKPAKDL 540
Query 526 RTKKVGKNEAVLEWDQLPVDVQNGFI 551
+ + W L +N I
Sbjct 541 TESVLLVGRRAVMWQSLEPAGENSMI 566
Score = 43.3 bits (100), Expect = 0.015, Method: Composition-based stats.
Identities = 51/349 (15%), Positives = 95/349 (27%), Gaps = 45/349 (13%)
Query 120 IISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLE-TNFTLKSEWAT-------HKFAD 171
+ + P P+N S V +++ W + E +TL + + +
Sbjct 1793 LTASATPSPPRNFSVRVLSPRELEVSWLPPEQLRSESVYYTLHWQQELDGENVQDRREWE 1852
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEA-ENALGKVTSDHINFDPVYKVKPNPPHNLSV 230
+R +WV+A +S+ ++ +
Sbjct 1853 AHERRLETAGTHRLTGIKPGSGYSLWVQAHATPTKSNSSERLHVRSFA-------ELPEL 1905
Query 231 INSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
E L LTW + ++ R+ + T V+ L+
Sbjct 1906 QLLELGPYSLSLTWAGTPDPLGSL---QLECRSSAEQLRRNVAGNHTKM-----VVEPLQ 1957
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE------DRPSKAPSFWYKIDPSHTQGY 344
P T Y R+ GY + T E D PS+ P
Sbjct 1958 PRTRYQCRL------LLGYAATPGAPLYHGTAEVYETLGDAPSQP------GKPQLEHIA 2005
Query 345 RTV-QLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVR 403
V ++ W A I Y + + +S ++ + + A V
Sbjct 2006 EEVFRVTWTAARGNGA--PIALYNLEALQARSDIRRRRRRRRRNSGGSLEQLPWAEEPVV 2063
Query 404 NLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
D T +C ++ H L + L W E ++
Sbjct 2064 VEDQWLDFCNTTELSCIVKSLHSSRLLLFRVRARSLEHGWGPYSEESER 2112
>sp|B4HY03|IHOG_DROSE Interference hedgehog OS=Drosophila sechellia
OX=7238 GN=iHog PE=3 SV=1
Length=880
Score = 65.3 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 34/198 (17%), Positives = 64/198 (32%), Gaps = 26/198 (13%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR--- 479
P + D + + W PR ++ + V +WQ + +
Sbjct 461 PPTPPNVTRL--SDESVMLRWMVPRNGGLPIVI-FKVQYRMVGKRKNWQTTNDNIPYGKP 517
Query 480 ----------TYLRGNLAESKCYLITVTPV--YADGPGSPESIKAYLKQAP---PSKGPT 524
T +L Y + V D S S K YL+ P P
Sbjct 518 KWNSELGKSFTASVTDLKPEHTYRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPE 577
Query 525 -VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSH-TEYTLS 580
+ ++ + VL W L D I Y +YR G ++ +H + ++
Sbjct 578 LLEIEEYSETAVVLHWS-LASDADEHLITGYYAYYRPSSSAGEYFKATIEGAHARSFKIA 636
Query 581 SLTSDTLYMVRMAAYTDE 598
L + T+Y ++ +++
Sbjct 637 PLETATMYEFKLQSFSAV 654
Score = 60.3 bits (144), Expect = 6e-08, Method: Composition-based stats.
Identities = 50/275 (18%), Positives = 81/275 (29%), Gaps = 46/275 (17%)
Query 196 VWVEAENALGKVTS-DHINFDP-----------VYKVKPN---------PPHNLSVINSE 234
V A N LG+ ++ + +P ++ KPN PP +V
Sbjct 412 VQCFARNRLGEHSAGTLLQVNPKQIQEPRESGGTHRPKPNQGSKQKQMYPPTPPNVTRLS 471
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS-TWSQIPPEDTAST---------RSSF 284
+ S + L W P + I+ + +QYR W +
Sbjct 472 DES--VMLRWMVPRNGGLPIVIFKVQYRMVGKRKNWQTTNDNIPYGKPKWNSELGKSFTA 529
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR-PSKAPSFWYKIDPSHTQG 343
+V DLKP Y FRI + + S+ S + P P + S T
Sbjct 530 SVTDLKPEHTYRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPELLEIEEYSET-- 587
Query 344 YRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN-------ATKLTVNLTNDRY 396
V L W + + I Y S + + + K+ T Y
Sbjct 588 --AVVLHWSLASDADEH-LITGYYAYYRPSSSAGEYFKATIEGAHARSFKIAPLETATMY 644
Query 397 LATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
L + V S+ + L T +
Sbjct 645 EFKLQSFSAVSASEFSALKQGRTQRPKTSTTEEPT 679
>sp|Q13203|MYBPH_HUMAN Myosin-binding protein H OS=Homo sapiens
OX=9606 GN=MYBPH PE=1 SV=4
Length=477
Score = 64.5 bits (155), Expect = 3e-09, Method: Composition-based stats.
Identities = 52/327 (16%), Positives = 113/327 (35%), Gaps = 22/327 (7%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK-Y 257
+A S P + P+ P L++ + S + W P + L+ Y
Sbjct 48 QAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVS--WEPPERLGRLGLQGY 105
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
++ + AS W +P + TV++L +++ R+ + G G + +
Sbjct 106 VLELCREGASEW--VPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPI 163
Query 318 SGITYEDRPS-KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA----NGKILDYE-VTLT 371
+ P + P + +Q+ ++ P +A NG LD + V++
Sbjct 164 HIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMR 223
Query 372 RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
+ +A + + RY T+ V +L K+ +L I ++ ++D+
Sbjct 224 TGDQDSILFIRSAQR----SDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVW 279
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
++WT P+++ +L + V + + T +L
Sbjct 280 GCNAA----LQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNS 335
Query 492 YLITVTPVYADGPGSPESIKAYLKQAP 518
Y V G + ++ K+
Sbjct 336 YSFRVFSENLCGLSTSATV---TKELA 359
Score = 39.5 bits (90), Expect = 0.15, Method: Composition-based stats.
Identities = 36/259 (14%), Positives = 79/259 (31%), Gaps = 16/259 (6%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTD 93
++ + Q+ + K W N + ++ ++ S+ F
Sbjct 182 QTYIRQVGETVNLQIPFQGK-------PKPQATWTHNGHALDSQRVSMRTGDQDSILFIR 234
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH 153
A + + + + I I+ P P ++ + G +W ++T
Sbjct 235 SAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTG 294
Query 154 LETN---FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD 210
T + ++ +R PT+CT+ + + V +EN G TS
Sbjct 295 -NTELLGYMVQKADKKTGQWFTVLERYHPTTCTIS-DLIIGNSYSFRVFSENLCGLSTSA 352
Query 211 HINFDPVYKVKPN----PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA 266
+ + + K + P + SE S L + L +++ K
Sbjct 353 TVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPK 412
Query 267 STWSQIPPEDTASTRSSFT 285
W + E + +
Sbjct 413 IIWMKNKMEIQGNPKYRAL 431
Score = 36.4 bits (82), Expect = 1.5, Method: Composition-based stats.
Identities = 18/108 (17%), Positives = 37/108 (34%), Gaps = 10/108 (9%)
Query 497 TPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
T A P P + PS + V + + W+ + G ++ Y +
Sbjct 56 TASTATKPAPPS-------EDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLG-LQGYVL 107
Query 557 FY-RTIIGNETAVNVDSSH-TEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
R V+ T+ T+ +L +++R++A + G
Sbjct 108 ELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGP 155
>sp|P24394|IL4RA_HUMAN Interleukin-4 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL4R PE=1 SV=1
Length=825
Score = 64.9 bits (156), Expect = 3e-09, Method: Composition-based stats.
Identities = 41/196 (21%), Positives = 67/196 (34%), Gaps = 14/196 (7%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSE--WATHKFADCKAKRDTPTSCTVDY- 186
+ +C+ + CEW T+ T L + + + C + + C
Sbjct 30 QEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLL 89
Query 187 --STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
V N + + A G+ +F P VKP P NL+V +S L LTW
Sbjct 90 MDDVVSADNYTLDLWA----GQQLLWKGSFKPSEHVKPRAPGNLTVH--TNVSDTLLLTW 143
Query 245 TNPSIKSVII---LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+NP + L Y + +++ +I LK Y R+R
Sbjct 144 SNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISYRARVRA 203
Query 302 MKEDGKGYWSDWSEEA 317
+ WS+WS
Sbjct 204 WAQCYNTTWSEWSPST 219
Score = 51.8 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 26/159 (16%), Positives = 50/159 (31%), Gaps = 11/159 (7%)
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWD-QLPVDVQNGFIRNYTI-FYRTIIGNETAV-NV 570
+ P + + +L W P D Y + + + + NV
Sbjct 118 SEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNV 177
Query 571 DSSHTEYTL--SSLTSDTLYMVRMAA----YTDEGGKDGPEFTFTTPKFAQGEIEAIVVP 624
+ S+L S Y R+ A Y + P + E ++
Sbjct 178 TYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSYREPFEQHLLLGV 237
Query 625 VCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHI 663
++ + L C+ IKK W +P+P++S +
Sbjct 238 SVSCIVILAV--CLLCYVSITKIKKEWWDQIPNPARSRL 274
>sp|Q63257|IL4RA_RAT Interleukin-4 receptor subunit alpha OS=Rattus
norvegicus OX=10116 GN=Il4r PE=2 SV=2
Length=801
Score = 64.1 bits (154), Expect = 4e-09, Method: Composition-based stats.
Identities = 40/192 (21%), Positives = 70/192 (36%), Gaps = 10/192 (5%)
Query 133 SCIVNEGKKMRCEWDGGRETHLETNFTLKSE--WATHKFADCKAKRDTPTSCTVDYSTVY 190
+C + + CEW + L + + C K T C +
Sbjct 33 TCFSDYIRTSTCEWQLDSTVDCSSQLLLDYRLLFEFSENLTCTPKNSADTVCVCQMAIEE 92
Query 191 FVNI-EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+ W+E + G++ +F P VKP P NL++ +S+ L L W+NP
Sbjct 93 PIQADTYWLELWSERGQLW--QGSFKPSDNVKPPAPDNLTLH--TNVSNALLLMWSNPYP 148
Query 250 KSVII---LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ + L + +D ++ + SF V L Y R+R + +
Sbjct 149 SNNFLHKGLICMVNISREDNPAEFKVYNVTYTEPKLSFPVNTLTSGVRYRARVRVLSQSF 208
Query 307 KGYWSDWSEEAS 318
G WS+WS +
Sbjct 209 PGIWSEWSPSIT 220
Score = 44.1 bits (102), Expect = 0.007, Method: Composition-based stats.
Identities = 29/157 (18%), Positives = 51/157 (32%), Gaps = 15/157 (10%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQ---NGFIRNYTIFYRTIIGNETAV---NVDS 572
P + N +L W G I I R E V
Sbjct 123 PPAPDNLTLHTNVSNALLLMWSNPYPSNNFLHKGLICMVNIS-REDNPAEFKVYNVTYTE 181
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTP-----KFAQGEIEAIVVPVCL 627
+ +++LTS Y R+ + G ++ F ++ + + V +
Sbjct 182 PKLSFPVNTLTSGVRYRARVRVLS--QSFPGIWSEWSPSITWYNHFQLPLLQRLPLGVSI 239
Query 628 AFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIA 664
+ + L L C+ IKK W +P P++S +A
Sbjct 240 SCICILLF-CLTCYFSIIKIKKIWWDQIPTPARSPLA 275
>sp|B4JEF2|IHOG_DROGR Interference hedgehog OS=Drosophila grimshawi
OX=7222 GN=iHog PE=3 SV=1
Length=888
Score = 64.1 bits (154), Expect = 5e-09, Method: Composition-based stats.
Identities = 46/274 (17%), Positives = 84/274 (31%), Gaps = 53/274 (19%)
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRE---SVKKYILEWCVLSDKAPCITDWQQEDGT 476
Q P D + + W +K + +++ +L+ WQ +
Sbjct 445 QTQMVPPSAPNVTRLSDESVMLRWHVMPNEGLPIKFFKVQYRMLTGTG---KSWQTTNEN 501
Query 477 VHRTYLR-------------GNLAESKCYLITVTPV--YADGPGSPESIKAYLKQAP--- 518
+ R L + Y + V D S S K +L++
Sbjct 502 IPYGKERNDYGAVKNFTSSVTGLRPDRRYRFRIMAVYSNNDNKESNTSGKFFLQRGATLA 561
Query 519 PSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVD-SSH 574
P P+ V ++ + VL WD L D I Y +YR G +D +
Sbjct 562 PLAVPSLVDIEEYSQTAVVLHWD-LTSDADEDLISGYYAYYRPSASAGEYLKATIDGAKS 620
Query 575 TEYTLSSLTSDTLYMVRMAAYTDE----------GGKDGPEFTFTTP-------KFAQGE 617
+ +S+L T+Y ++ +++ G P + TT
Sbjct 621 RSFQISALEPGTIYEFKLQSFSAVAASEFSALKQGRTQRPRVSTTTEPAVHAMDTTTPSH 680
Query 618 IEAIVVPVCL-------AFLLTTLLGVLFCFNKR 644
E + L A L+ ++ C +R
Sbjct 681 NETFNLNPLLTGTIGGGALLVLLVVSACLCLCRR 714
Score = 62.6 bits (150), Expect = 2e-08, Method: Composition-based stats.
Identities = 68/457 (15%), Positives = 123/457 (27%), Gaps = 77/457 (17%)
Query 36 PVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIA 95
V ++ + +C + +W + + + NRT I
Sbjct 245 KVARVGESVLLLC-------PGVGCPSPTAIWSSPNVPGAIKN----NRTRVLPYGLQIN 293
Query 96 SLNIQLTCNILTF---GQLEQNVYGITIISGLPPEKPKNLSCI-VNEGKKMRCEWDGGRE 151
L + + G + I ++ P S NEG+ M+ E
Sbjct 294 ELQALDGGTYICYLDNGIRPALKHSIQLLVQQAPRIVLAPSANLTNEGEAMQLE---CVA 350
Query 152 THLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS-D 210
T + + + A+ + S V A N+LG+ ++
Sbjct 351 TGIP-EPEIYWLLNGNNSANDSKANPGSNGILILQSVQKRHAGYVQCFARNSLGEDSAGT 409
Query 211 HINFDPVYK------------VKPN---------------PPHNLSVINSEELSSILKLT 243
+ +P V+P PP +V + S + L
Sbjct 410 ILQVNPTQIQTGDGGGGSRAYVRPQQHMFGRKQKQQTQMVPPSAPNVTRLSDES--VMLR 467
Query 244 WTNPSIKSVIILKYNIQYR--TKDASTWSQIPPEDTASTRS---------SFTVQDLKPF 292
W + + I + +QYR T +W + +V L+P
Sbjct 468 WHVMPNEGLPIKFFKVQYRMLTGTGKSWQTTNENIPYGKERNDYGAVKNFTSSVTGLRPD 527
Query 293 TEYVFRIRCMKEDGKGYWSDWSEE---ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL 349
Y FRI + + S+ S + G T P PS + S T V L
Sbjct 528 RRYRFRIMAVYSNNDNKESNTSGKFFLQRGATL--APLAVPSLVDIEEYSQT----AVVL 581
Query 350 VWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN-------ATKLTVNLTNDRYLATLTV 402
W + + I Y S + + +++ Y L
Sbjct 582 HWDLTSDADED-LISGYYAYYRPSASAGEYLKATIDGAKSRSFQISALEPGTIYEFKLQS 640
Query 403 RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNML 439
+ V S+ + L + D
Sbjct 641 FSAVAASEFSALKQGRTQRPRVSTTTEPAVHAMDTTT 677
>sp|Q9VM64|IHOG_DROME Interference hedgehog OS=Drosophila melanogaster
OX=7227 GN=ihog PE=1 SV=1
Length=886
Score = 63.7 bits (153), Expect = 7e-09, Method: Composition-based stats.
Identities = 34/193 (18%), Positives = 61/193 (32%), Gaps = 26/193 (13%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR--- 479
P + D + + W PR ++ + V +WQ + +
Sbjct 467 PPTPPNVTRL--SDESVMLRWMVPRNDGLPIVI-FKVQYRMVGKRKNWQTTNDNIPYGKP 523
Query 480 ----------TYLRGNLAESKCYLITVTPV--YADGPGSPESIKAYLKQAP---PSKGPT 524
T +L Y + V D S S K YL+ P P
Sbjct 524 KWNSELGKSFTASVTDLKPQHTYRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPE 583
Query 525 -VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVDSSH-TEYTLS 580
+ ++ + VL W L D I Y +YR G ++ +H + ++
Sbjct 584 LLEIEEYSETAVVLHWS-LASDADEHLITGYYAYYRPSSSAGEYFKATIEGAHARSFKIA 642
Query 581 SLTSDTLYMVRMA 593
L + T+Y ++
Sbjct 643 PLETATMYEFKLQ 655
Score = 56.0 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 63/419 (15%), Positives = 118/419 (28%), Gaps = 70/419 (17%)
Query 5 QTWLVQALFIFLTTESTGELLDPC---GYISPESPVVQLHSNFTAVCVLKEKCMDYFHVN 61
+ L +L + +T E E P G S + ++ S+ +C
Sbjct 236 RIQLPGSLQLQVTPEQRSESKSPHLLRGQPSSQEITIREGSSLLLLC-------PGVGSP 288
Query 62 ANYIVWKTNHF--TIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGIT 119
+VW + + ++ + +I++ + + F
Sbjct 289 PPTVVWSSPDVVGAVKNKRSKVFGHA------LEISNTRVNDAGTYICFQDNGVRPALEH 342
Query 120 IISGLPPEKPKNLSCIVNEGKK------MRCEWDGGRETHLETNFTLKSEWATHKFADCK 173
I + P+ + + + C + T + T + H D
Sbjct 343 YIKVHVEQPPQIVRPPWADLTNEGDRLKLEC-----KATGVPT-PEIYWLLNGHSSIDDS 396
Query 174 AKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS-DHINFDP-----------VYKVK 221
+ + V A N LG+ ++ + +P ++ K
Sbjct 397 EAELSNNFLILHSVLKRHAGY-VQCFARNRLGEHSAGTLLQVNPKQIQEPRESGGTHRPK 455
Query 222 PN---------PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS-TWSQ 271
PN PP +V + S + L W P + I+ + +QYR W
Sbjct 456 PNQGSRQKQMYPPTPPNVTRLSDES--VMLRWMVPRNDGLPIVIFKVQYRMVGKRKNWQT 513
Query 272 IPPEDTAST---------RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ +V DLKP Y FRI + + S+ S +
Sbjct 514 TNDNIPYGKPKWNSELGKSFTASVTDLKPQHTYRFRILAVYSNNDNKESNTSAKFYLQPG 573
Query 323 EDR-PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY 380
P P + S T V L W + + I Y S + +
Sbjct 574 AALDPMPVPELLEIEEYSET----AVVLHWSLASDADEH-LITGYYAYYRPSSSAGEYF 627
>sp|E7FF10|VWA1_DANRE von Willebrand factor A domain-containing
protein 1 OS=Danio rerio OX=7955 GN=vwa1 PE=3 SV=1
Length=503
Score = 63.0 bits (151), Expect = 7e-09, Method: Composition-based stats.
Identities = 38/255 (15%), Positives = 80/255 (31%), Gaps = 26/255 (10%)
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST-------- 280
+ S+ +L W P + Y+I++ +P +
Sbjct 221 RLQVKSVSSTSAQLEWR-PVLSGSGSGYYDIKFGPMRTGQIPGVPGGASTDPGSFQRITR 279
Query 281 ---RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
SS + L+P T Y + + + S T P +
Sbjct 280 PADSSSAQLTGLRPDTTYTVTLTPKNNQQV----LNTLQTSFTTQTVNPPEPQIQLLSSL 335
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNY-----TVNATKLTVNLT 392
+V++ W L P I +Y++ + S T N+T +T
Sbjct 336 SVSESSSNSVRVSWAPLLPRL----IQEYQLEYSALPSGPLRVLRVSNTHNSTVITDLQP 391
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
+ +YL T++ + GK A + + + + L + D + + W + ++
Sbjct 392 DTQYLLTVSAKQTSGKERAMTVKVCTQEVLPALSDLQLSSVG-DETVQLRWKGSFDGLRG 450
Query 453 YILEWCVLSDKAPCI 467
Y + W + +
Sbjct 451 YWVTWERGHSQRSTL 465
Score = 60.6 bits (145), Expect = 4e-08, Method: Composition-based stats.
Identities = 42/288 (15%), Positives = 88/288 (31%), Gaps = 36/288 (13%)
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH-------------------LQ 378
+ + QL W+ + +G Y++ ++ +
Sbjct 223 QVKSVSSTSAQLEWRPVLSGSGSGY---YDIKFGPMRTGQIPGVPGGASTDPGSFQRITR 279
Query 379 NYTVNATKLTVNLTNDRYLATLTVRNLVG-----KSDAAVLTIPACDFQATHPVMDLKAF 433
++ +LT + Y TLT +N ++ T+ + Q +
Sbjct 280 PADSSSAQLTGLRPDTTYTVTLTPKNNQQVLNTLQTSFTTQTVNPPEPQIQLLSSLSVSE 339
Query 434 PKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYL 493
N + V W + + I E+ + P H + + +L YL
Sbjct 340 SSSNSVRVSWAP---LLPRLIQEYQLEYSALPSGPLRVLRVSNTHNSTVITDLQPDTQYL 396
Query 494 ITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
+TV+ G ++K ++ P ++ VG L W +G +R
Sbjct 397 LTVSAKQTSGKERAMTVKVCTQEVLP-ALSDLQLSSVGDETVQLRWKG----SFDG-LRG 450
Query 554 YTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
Y + + + + + + TL+ + S V T G
Sbjct 451 YWVTWERGHSQRSTLYLPPNRLSTTLNHVPSRARVCVSPVYRTARGEG 498
Score = 57.9 bits (138), Expect = 3e-07, Method: Composition-based stats.
Identities = 48/286 (17%), Positives = 90/286 (31%), Gaps = 35/286 (12%)
Query 132 LSCIVNEGKKMRCEWDGGRETHLETNFTLK-SEWATHKFADCKA------------KRDT 178
L + EW + +K T + R
Sbjct 222 LQVKSVSSTSAQLEWRPVLSGSGSGYYDIKFGPMRTGQIPGVPGGASTDPGSFQRITRPA 281
Query 179 PTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH--NLSVINSEEL 236
+S V + +N + + +F P P S+ SE
Sbjct 282 DSSSAQLTGLRPDTTYTVTLTPKNNQQVLNTLQTSFTTQTVNPPEPQIQLLSSLSVSESS 341
Query 237 SSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
S+ ++++W + +I +Y ++Y + + ++T +S + DL+P T+Y+
Sbjct 342 SNSVRVSWAP--LLPRLIQEYQLEYSALPSGP---LRVLRVSNTHNSTVITDLQPDTQYL 396
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
+ + GK + + T E P+ + G TVQL WK
Sbjct 397 LTVSAKQTSGK----ERAMTVKVCTQEVLPA------LSDLQLSSVGDETVQLRWKGSFD 446
Query 357 FEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTV 402
+ Y VT R S + +L+ L + A + V
Sbjct 447 G-----LRGYWVTWERGHSQRSTLYLPPNRLSTTLNHVPSRARVCV 487
Score = 50.6 bits (119), Expect = 6e-05, Method: Composition-based stats.
Identities = 26/171 (15%), Positives = 51/171 (30%), Gaps = 11/171 (6%)
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
P L G L Y +T+TP + + P +
Sbjct 268 STDPGSFQRITRPADSSSAQLTG-LRPDTTYTVTLTPKNNQQVLNTLQTSFTTQTVNPPE 326
Query 522 GP-----TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI-IGNETAVNVDSSHT 575
++ + N + W L I+ Y + Y + G + V ++H
Sbjct 327 PQIQLLSSLSVSESSSNSVRVSWAPLLPR----LIQEYQLEYSALPSGPLRVLRVSNTHN 382
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVC 626
++ L DT Y++ ++A G + T + + + V
Sbjct 383 STVITDLQPDTQYLLTVSAKQTSGKERAMTVKVCTQEVLPALSDLQLSSVG 433
Score = 39.5 bits (90), Expect = 0.14, Method: Composition-based stats.
Identities = 20/108 (19%), Positives = 37/108 (34%), Gaps = 18/108 (17%)
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT---------------IIGNETAVN 569
++ K V A LEW + +G+ Y I + G+ +
Sbjct 222 LQVKSVSSTSAQLEWRPVLSGSGSGY---YDIKFGPMRTGQIPGVPGGASTDPGSFQRIT 278
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
+ + L+ L DT Y V + ++ + + +FTT E
Sbjct 279 RPADSSSAQLTGLRPDTTYTVTLTPKNNQQVLNTLQTSFTTQTVNPPE 326
>sp|Q9D2H5|TRI42_MOUSE Tripartite motif-containing protein 42
OS=Mus musculus OX=10090 GN=Trim42 PE=2 SV=2
Length=723
Score = 63.3 bits (152), Expect = 8e-09, Method: Composition-based stats.
Identities = 20/104 (19%), Positives = 45/104 (43%), Gaps = 10/104 (10%)
Query 213 NFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQI 272
+F+ P P + + + K+ WT P+ + + +++ + + +
Sbjct 595 SFNDTSVRTPGP---IVIYQTLVYPRAAKVYWTCPTE---DVDSFEMEFYELVTTPPNNV 648
Query 273 PPEDT----ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
E + + + +L P TEY+F++R + ++G G WSD
Sbjct 649 RTELCGQIRDILQQNLELHNLTPNTEYLFKVRAINDNGPGQWSD 692
Score = 37.9 bits (86), Expect = 0.45, Method: Composition-based stats.
Identities = 18/68 (26%), Positives = 27/68 (40%), Gaps = 3/68 (4%)
Query 441 VEWTTPRESVKKYILEWCVLSDKAPCITDWQ---QEDGTVHRTYLRGNLAESKCYLITVT 497
V WT P E V + +E+ L P + Q + + NL + YL V
Sbjct 621 VYWTCPTEDVDSFEMEFYELVTTPPNNVRTELCGQIRDILQQNLELHNLTPNTEYLFKVR 680
Query 498 PVYADGPG 505
+ +GPG
Sbjct 681 AINDNGPG 688
>sp|Q04790|INAR1_BOVIN Interferon alpha/beta receptor 1 OS=Bos
taurus OX=9913 GN=IFNAR1 PE=2 SV=2
Length=560
Score = 63.0 bits (151), Expect = 9e-09, Method: Composition-based stats.
Identities = 75/484 (15%), Positives = 149/484 (31%), Gaps = 43/484 (9%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP-EDTASTRSS 283
P N+ + ++ L W + S +SV + ++ Y+ W ++ + ST+ +
Sbjct 30 PENVEIHIIDDN---FFLKWNS-SSESVKNVTFSADYQILGTDNWKKLSGCQHITSTKCN 85
Query 284 FTVQDLKP-FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSF-----WYKID 337
F+ +L+ F + RIR + + S W E + + + P I
Sbjct 86 FSSVELENVFEKIELRIRAEEGNNT---STWYEVEPFVPFLEAQIGPPDVHLEAEDKAII 142
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA-TKLTVNLTNDRY 396
S + ++W Y V + + S L+ T + + +
Sbjct 143 LSISPPGTKDSIMWAMDRSS------FRYSVVIWKNSSSLEERTETVYPEDKIYKLSPEI 196
Query 397 LATLTVRNLVGKSD-----AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK 451
L V+ + + V I + +++ + + ++W P E+
Sbjct 197 TYCLKVKAELRLQSRVGCYSPVYCINTTERHKVPSPENIQINADNQIYVLKWDYPYENAT 256
Query 452 KYILEWCVLSDKAPC--ITDWQQED--GTVHRTY--LRGNLAESKCYLITVTPVYADGPG 505
K P W+Q V T+ ++ Y + V +G
Sbjct 257 FQAQWLRAFFKKIPGNHSDKWKQIPNCENVTSTHCVFPREVSSRGIYYVRVRASNGNGTS 316
Query 506 S-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN 564
E + + P + K V + + + Y + Y I
Sbjct 317 FWSEEKEFNTEMKTIIFPPVISVKSVTDDSLHVSVGASEESENMSVNQLYPLIYEVIFWE 376
Query 565 ET---AVNVDSSHTEYTLSSLTSDTLYMVRMAAY--TDEGGKDGPEFTFTTPKFAQGEIE 619
T V T + L T+Y V+ A D K K G
Sbjct 377 NTSNAERKVLEKRTNFIFPDLKPLTVYCVKARALIENDRRNKGSSFSDTVCEKTKPGNTS 436
Query 620 --AIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFN 677
++V C A ++ + R +K +P+ P S + ++ P R+
Sbjct 437 KTWLIVGTCTALFSIPVVIYVVSVFLRC-VKYVFFPSSKPP--SSVDEYFSDQPLRNLLL 493
Query 678 SKDQ 681
S +
Sbjct 494 STSE 497
Score = 49.5 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 34/185 (18%), Positives = 60/185 (32%), Gaps = 7/185 (4%)
Query 167 HKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPP 225
+ +C+ T C V V A N G S+ F+ K PP
Sbjct 278 KQIPNCENVTSTH--CVFPREVSSRGIYYVRVRASNGNGTSFWSEEKEFNTEMKTIIFPP 335
Query 226 HNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
+SV + + S + + + S + Y + Y S + R++F
Sbjct 336 V-ISVKSVTDDSLHVSVGASEESENMSVNQLYPLIYEVIFWENTSNAERK-VLEKRTNFI 393
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
DLKP T Y + R + E+ + S + + + +P W +
Sbjct 394 FPDLKPLTVYCVKARALIENDRRN--KGSSFSDTVCEKTKPGNTSKTWLIVGTCTALFSI 451
Query 346 TVQLV 350
V +
Sbjct 452 PVVIY 456
Score = 43.7 bits (101), Expect = 0.007, Method: Composition-based stats.
Identities = 35/220 (16%), Positives = 67/220 (30%), Gaps = 15/220 (7%)
Query 192 VNIEVWVEAENALGKVT---SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
+ + V+AE L S + + K P N+ + ++ L W P
Sbjct 196 ITYCLKVKAELRLQSRVGCYSPVYCINTTERHKVPSPENIQINADNQIY---VLKWDYPY 252
Query 249 IKSVI----ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ + + + + W QIP + ++ +++ Y R+R
Sbjct 253 ENATFQAQWLRAFFKKIPGNHSDKWKQIPNCENVTSTHCVFPREVSSRGIYYVRVRASNG 312
Query 305 DGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
+G S WSEE T E + P + + +V ++ L
Sbjct 313 NGT---SFWSEEKEFNT-EMKTIIFPPVISVKSVTDDSLHVSVGASEESENMSVNQLYPL 368
Query 365 DYEVTLTRWKSHLQN-YTVNATKLTVNLTNDRYLATLTVR 403
YEV S+ + T + + R
Sbjct 369 IYEVIFWENTSNAERKVLEKRTNFIFPDLKPLTVYCVKAR 408
>sp|P04157|PTPRC_RAT Receptor-type tyrosine-protein phosphatase
C OS=Rattus norvegicus OX=10116 GN=Ptprc PE=1 SV=2
Length=1273
Score = 63.3 bits (152), Expect = 9e-09, Method: Composition-based stats.
Identities = 51/313 (16%), Positives = 105/313 (34%), Gaps = 42/313 (13%)
Query 120 IISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTP 179
I +PP + C + T+ L+ + +KF K
Sbjct 259 INLDVPPG--------THNFNLTNCT----PDIEANTSICLEWK-IKNKFTCDIQKISYN 305
Query 180 TSCTVD--------YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPN---PPHNL 228
CT + + T++ N+ V A + ++ I +V+ + P
Sbjct 306 FRCTPEMKTFALDKHGTLWLHNLTVRTNYTCAAEVLYNNVILLKQDRRVQTDFGTPEMLP 365
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
V +S ++W P+ K Y + Y+ + E+ A+ +SF V++
Sbjct 366 HVQCKNSTNSTTLVSWAEPASKHH---GYILCYKKTPSE-----KCENLANDVNSFEVKN 417
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
L+P+TEY + G+ + +++ + T RP K + ++
Sbjct 418 LRPYTEYTVSLFAY-VIGRVQRNGPAKDCNFRTKAARPGK-----VNGMKTSRASDNSIN 471
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT--NDRYLATLTVRNLV 406
+ P+E NG Y + + S ++ + + K V+ + Y + N
Sbjct 472 VT--CNSPYEINGPEARYILEVKSGGSLVKTFNQSTCKFVVDNLYYSTDYEFLVYFYNGE 529
Query 407 GKSDAAVLTIPAC 419
D +
Sbjct 530 YLGDPEIKPQSTS 542
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 35/214 (16%), Positives = 66/214 (31%), Gaps = 19/214 (9%)
Query 416 IPACDFQATHPVMDLKAFPKD----NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
I D +L D + +EW + K+ + +S C + +
Sbjct 258 IINLDVPPGTHNFNLTNCTPDIEANTSICLEW----KIKNKFTCDIQKISYNFRCTPEMK 313
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
H T NL Y +Y + + + P P V+ K
Sbjct 314 TFALDKHGTLWLHNLTVRTNYTCAAEVLYNNVILLKQDRRVQTDFGTPEMLPHVQCKNST 373
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
+ ++ W + Y + Y+ + N+ + + + +L T Y V
Sbjct 374 NSTTLVSWAEPASKHH-----GYILCYKKTPSEKCE-NLANDVNSFEVKNLRPYTEYTVS 427
Query 592 MAAYTDEGGK--DGPEF--TFTTPKFAQGEIEAI 621
+ AY G +GP F T G++ +
Sbjct 428 LFAYV-IGRVQRNGPAKDCNFRTKAARPGKVNGM 460
Score = 38.7 bits (88), Expect = 0.31, Method: Composition-based stats.
Identities = 29/185 (16%), Positives = 55/185 (30%), Gaps = 12/185 (6%)
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKL 387
P + T + W P + +G IL Y+ T + +L N VN+ ++
Sbjct 359 GTPEMLPHV-QCKNSTNSTTLVSW-AEPASKHHGYILCYKKTPSEKCENLAN-DVNSFEV 415
Query 388 TVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL----KAFPKDNMLWVEW 443
Y +L ++G+ + + DN + V
Sbjct 416 KNLRPYTEYTVSLFAY-VIGRVQRNGPAKDCNFRTKAARPGKVNGMKTSRASDNSINVTC 474
Query 444 TTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADG 503
+P E + + + + + ++ NL S Y V +
Sbjct 475 NSPYE-INGPEARYILEVKSGGSLVKTFNQS---TCKFVVDNLYYSTDYEFLVYFYNGEY 530
Query 504 PGSPE 508
G PE
Sbjct 531 LGDPE 535
>sp|O01761|UNC89_CAEEL Muscle M-line assembly protein unc-89 OS=Caenorhabditis
elegans OX=6239 GN=unc-89 PE=1 SV=3
Length=8081
Score = 63.7 bits (153), Expect = 9e-09, Method: Composition-based stats.
Identities = 34/214 (16%), Positives = 62/214 (29%), Gaps = 18/214 (8%)
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLA 398
++ W GKIL+ +T + + + +L
Sbjct 7549 CAVSASPAPKVTWDF------QGKILESNDRVTIEQDNNVARLILNHAAPYDL----GEY 7598
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV----KKYI 454
T N G ++ I + D ++++W P Y
Sbjct 7599 VCTAINEYGTDKSSCRLISGETPSRPGRPEAELS--SDTEIFIQWEAPEGPTYLEGITYR 7656
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
LE+ V + + + +L+ Y VT G G P S+ + +
Sbjct 7657 LEYRVAGPNDHGDPWITVSEKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLP-SLSSRI 7715
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN 548
Q P ++ V K+E L +P N
Sbjct 7716 VQTHGKGAPKLQI-DVLKSEIRLNVVSMPQKSTN 7748
Score = 51.8 bits (122), Expect = 4e-05, Method: Composition-based stats.
Identities = 23/121 (19%), Positives = 36/121 (30%), Gaps = 13/121 (11%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKY 257
A N G S +P P + + + W P + + + Y
Sbjct 7601 TAINEYGTDKSSCRLISGETPSRPGRP-----EAELSSDTEIFIQWEAPEGPTYLEGITY 7655
Query 258 NIQYRTKD----ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
++YR W + + S V+ L P Y FR+ G G S
Sbjct 7656 RLEYRVAGPNDHGDPWITVSEKI---DDESVIVKHLSPLGIYQFRVTAQNGFGLGLPSLS 7712
Query 314 S 314
S
Sbjct 7713 S 7713
Score = 51.8 bits (122), Expect = 4e-05, Method: Composition-based stats.
Identities = 53/386 (14%), Positives = 104/386 (27%), Gaps = 75/386 (19%)
Query 199 EAENALGKVTS-----------DHINFDPVYKVKP---------------NP-PHNLSVI 231
A+N+ G +S D I F+ V P P P +
Sbjct 6224 TAKNSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEYGFKKLNTASLPTPPDRGPF 6283
Query 232 NSEELSSILKLTWTN--PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
E L L+W + + Y I+ R WS + V++L
Sbjct 6284 IKEVTGHYLTLSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNI---PEPVCKVRNL 6340
Query 290 KPFTEYVFRIRCMKEDGK----------GYWSDWSEEASGITYEDRPSKAP--------- 330
+ Y FR+R G + T + P P
Sbjct 6341 ELGKSYQFRVRAENIYGISDPSPASPPSRLMAPPQPVFDRRTNKVIPLLDPYAEKALDMR 6400
Query 331 ------------SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
+ T+ L P + K +++ + S +
Sbjct 6401 YSEQYACAPWFSPGVVEKRYCAENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCK 6460
Query 379 NYTVNATKLTVNLTN----DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMD---LK 431
YT ++ T+ +T + +N G + ++ A P+++
Sbjct 6461 VYTYGGSETTLAITGFSKENVGQYQCFAKNDYGDAQQNIMVDLATRPNFIQPLVNKTFSS 6520
Query 432 AFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
A P + V+ E K++ EW + + + Q+ + + +
Sbjct 6521 AQPMRMDVRVDGEPFPE--LKWMKEWRPIVES--SRIKFVQDGPYLCSLIINDPMWRDSG 6576
Query 492 YLITVTPVYADGPGSPESIKAYLKQA 517
+ + V G + +
Sbjct 6577 -IYSCVAVNDAGQATTSCTVTVEAEG 6601
Score = 47.9 bits (112), Expect = 6e-04, Method: Composition-based stats.
Identities = 29/204 (14%), Positives = 50/204 (25%), Gaps = 25/204 (12%)
Query 403 RNLVGKSDAAVLT-IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
+N G + + P + A V W + ILE
Sbjct 7520 KNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTW-----DFQGKILE----- 7569
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSK 521
E + + A T + G S + + PS+
Sbjct 7570 ----SNDRVTIEQDNNVARLILNHAAPYDLGEYVCTAINEYGTDKS-SCRLISGET-PSR 7623
Query 522 GPTVRTKKVGKNEAVLEWD-QLPVDVQNGFIRNYTIFYRTIIGN-----ETAVNVDSSHT 575
+ E ++W+ G Y + YR N V+
Sbjct 7624 PGRPEAELSSDTEIFIQWEAPEGPTYLEGIT--YRLEYRVAGPNDHGDPWITVSEKIDDE 7681
Query 576 EYTLSSLTSDTLYMVRMAAYTDEG 599
+ L+ +Y R+ A G
Sbjct 7682 SVIVKHLSPLGIYQFRVTAQNGFG 7705
Score = 46.0 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 20/108 (19%), Positives = 35/108 (32%), Gaps = 4/108 (4%)
Query 493 LITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
I VTP + G + + PP +GP ++ +V + L W
Sbjct 6253 EIDVTPYLTEEYGF-KKLNTASLPTPPDRGPFIK--EVTGHYLTLSWIPTKRAPPRYPQV 6309
Query 553 NYTIFYRTIIGN-ETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
Y I R + + + + + +L Y R+ A G
Sbjct 6310 TYVIEIRELPEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVRAENIYG 6357
Score = 38.7 bits (88), Expect = 0.40, Method: Composition-based stats.
Identities = 28/205 (14%), Positives = 53/205 (26%), Gaps = 40/205 (20%)
Query 353 TLPPFE--ANGK--ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK 408
P E NGK + + + + T L D T +N G
Sbjct 6177 PAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTL-----EDAGEYVATAKNSHGS 6231
Query 409 SDAAVL---TIPACDFQATHPVMDLKAF---------------------------PKDNM 438
+ ++ + T+P D + +D+ + +
Sbjct 6232 ASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEYGFKKLNTASLPTPPDRGPFIKEVTGHY 6291
Query 439 LWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV-HRTYLRGNLAESKCYLITVT 497
L + W + + +Y V+ + W + + NL K Y V
Sbjct 6292 LTLSWIPTKRAPPRYPQVTYVIEIRELPEKQWSLLEYNIPEPVCKVRNLELGKSYQFRVR 6351
Query 498 PVYADGPGSPESIKAYLKQAPPSKG 522
G P + P +
Sbjct 6352 AENIYGISDPSPASPPSRLMAPPQP 6376
>sp|A2AAJ9|OBSCN_MOUSE Obscurin OS=Mus musculus OX=10090 GN=Obscn
PE=1 SV=3
Length=8886
Score = 63.7 bits (153), Expect = 9e-09, Method: Composition-based stats.
Identities = 20/90 (22%), Positives = 32/90 (36%), Gaps = 6/90 (7%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P+PP + V+ + S + L+W P S + Y ++ + W
Sbjct 5469 PDPPEDAEVVGRSDHS--VTLSWVAPMSDGGGGLCGYRVEMKEASTGQWQLC---HDLVP 5523
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
V DL P Y FR+ + G G
Sbjct 5524 GPECVVDDLVPGKTYRFRVAAVGPAGAGEP 5553
Score = 57.9 bits (138), Expect = 6e-07, Method: Composition-based stats.
Identities = 22/108 (20%), Positives = 41/108 (38%), Gaps = 5/108 (5%)
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL--KYNIQYR 262
G T+ + PP + V E S + L+W+ P + Y ++ R
Sbjct 494 GCRTTTQFCVSAPRRPPLYPPADPVVKAKTE--SSVTLSWSAPPHGDRPVTIDGYVLEKR 551
Query 263 TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
A WS+ E + FT+ + ++ FR+ + G+G +
Sbjct 552 KLGAYAWSR-CHEAGWLATTEFTITGVAEEGDFQFRVSAINHFGQGPY 598
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 34/217 (16%), Positives = 53/217 (24%), Gaps = 22/217 (10%)
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD----NMLWVEWTTPR 447
D T ++V +A LT+ + P D +
Sbjct 5352 PQDSCRVTFLAGDVV---TSAFLTVRGWRLEVLEPPHDASVKAGMQVRFTCIL------S 5402
Query 448 ESVKKYILEWCVLSDK-APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
E+V W + P TDW H N +T A
Sbjct 5403 EAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQHAGEVTFAARDAVASAR 5462
Query 507 PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII-GNE 565
+ A P + L W P+ G + Y + + G
Sbjct 5463 LSVL------ALPDPPEDAEVVGRSDHSVTLSWVA-PMSDGGGGLCGYRVEMKEASTGQW 5515
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ E + L Y R+AA G +
Sbjct 5516 QLCHDLVPGPECVVDDLVPGKTYRFRVAAVGPAGAGE 5552
Score = 52.9 bits (125), Expect = 2e-05, Method: Composition-based stats.
Identities = 29/159 (18%), Positives = 50/159 (31%), Gaps = 11/159 (7%)
Query 352 KTLPPFEANGKILDYEV-TLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD 410
+ +P EA I + + + + +A L+ T R+ V +
Sbjct 5403 EAVPVGEATWYINGAAIQPDDTDWTVTTDGSHHALTLSNAQPQHAGEVTFAARDAVASAR 5462
Query 411 AAVLTIPACDFQATHPVMDLKAFPKDN-MLWVEWTTPRESVKKYILEWCVLSDKAPCITD 469
+VL +P P D + + + + + W P + + V K
Sbjct 5463 LSVLALPD-------PPEDAEVVGRSDHSVTLSWVAPMSDGGGGLCGYRVEM-KEASTGQ 5514
Query 470 WQQ-EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
WQ D + +L K Y V V G G P
Sbjct 5515 WQLCHDLVPGPECVVDDLVPGKTYRFRVAAVGPAGAGEP 5553
Score = 48.3 bits (113), Expect = 5e-04, Method: Composition-based stats.
Identities = 91/639 (14%), Positives = 167/639 (26%), Gaps = 115/639 (18%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPK--EQYTIINRTASSVT 90
P++ VV + + T C + HV+ W+ + + + +T
Sbjct 15 PKAFVVSVGKDATLSCQIVGN--PTPHVS-----WEKDRQPVEAGARFRLAQDGDVYRLT 67
Query 91 FTDIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPEK--------PKNLSCIVNEGKK 141
D+A + Q C G+ + S + P ++
Sbjct 68 ILDLALGDSGQYVCRARNAIGEAFAAVGLRVDSEGTCAEQAPHFLLRPTSIRVREGADAT 127
Query 142 MRC----------EWDG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY 190
RC W GR ++ E A + + P
Sbjct 128 FRCRVGGSPQPAVSWSKDGRRLGPPDAPHVRVEEHGESSA-LRIRSARPRD--------- 177
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVI------------------- 231
V AEN LG ++ PP +
Sbjct 178 --GGTYEVRAENPLGSASAAAALVVDSDAEVAGPPGTSTATLLAHLQQRREAMRAEGIPP 235
Query 232 -NSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ +T L + K + W + T R + +
Sbjct 236 SPPGAGTRTCTVT-----EGKHARLSCFVTGEPKPETVWKKDGQLVTEGRRHVVYEDEQE 290
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED-----RPSKAPSFWYKIDPSHTQGYR 345
+V +I K+ +G ++ + G TY R P D +
Sbjct 291 ---NFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPTVPFKKRLQDLEVREKES 347
Query 346 TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNL 405
P EA ++ W S + T+ LTVRN
Sbjct 348 ATFQCEVAQPATEAAW----FKEETRLWASAKYDIEEEGTER-----------RLTVRN- 391
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE---SVKKYILEWCVLSD 462
V D AV + T + ++ + PR+ + W L+
Sbjct 392 VSADDDAVYICETTEGSRTVAELSVQG-------NLTRKLPRKTAVRTGDTAIFWVELAV 444
Query 463 KAPCITDWQQEDGTV--HRTYLRGNLAESKCYLITVT-------PVYADGPGSPESIKAY 513
+ + ++ V R + + T + G +
Sbjct 445 PEGPVRWLRNQEEMVAGGRVAITAEGTCHTLTIFQCTLEDMGEVAFVSGGCRTTTQFCVS 504
Query 514 LKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIG---NETAVN 569
+ PP P K ++ L W P + I Y + R + +
Sbjct 505 APRRPPLYPPADPVVKAKTESSVTLSWSAPPHGDRPVTIDGYVLEKRKLGAYAWSRCHEA 564
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTF 608
+ TE+T++ + + + R++A G GP F
Sbjct 565 GWLATTEFTITGVAEEGDFQFRVSAINHFG--QGPYLEF 601
Score = 44.8 bits (104), Expect = 0.005, Method: Composition-based stats.
Identities = 20/121 (17%), Positives = 39/121 (32%), Gaps = 4/121 (3%)
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
++ G+ + K PS P ++ K+ +L W + G + Y +
Sbjct 8454 CVSNPLGTAVTTGVLRKAERPSSSPRPEVGELYKDAVLLVWKPV---ESCGPVT-YIVQC 8509
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEI 618
G+ T + D S Y L+ +Y+ R A + G + +
Sbjct 8510 CIEGGSWTTLASDISDCCYLTGKLSRGGMYIFRTACVSKAGMGPYSSPSEQVLLGGPNHL 8569
Query 619 E 619
Sbjct 8570 A 8570
Score = 44.8 bits (104), Expect = 0.005, Method: Composition-based stats.
Identities = 22/119 (18%), Positives = 39/119 (33%), Gaps = 11/119 (9%)
Query 199 EAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
N LG + + P + E + L W P + Y
Sbjct 8454 CVSNPLGTAVTTGVLRKAE-----RPSSSPRPEVGELYKDAVLLVWK-PVESCGPVT-YI 8506
Query 259 IQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA 317
+Q + S W+ + + + + L Y+FR C+ + G G +S SE+
Sbjct 8507 VQCCIEGGS-WTTLASDI---SDCCYLTGKLSRGGMYIFRTACVSKAGMGPYSSPSEQV 8561
>sp|H2KZM6|PTPR_CAEEL Receptor-type tyrosine-protein phosphatase
OS=Caenorhabditis elegans OX=6239 GN=clr-1 PE=1 SV=1
Length=1409
Score = 63.3 bits (152), Expect = 1e-08, Method: Composition-based stats.
Identities = 45/346 (13%), Positives = 95/346 (27%), Gaps = 63/346 (18%)
Query 207 VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA 266
++ ++ + + P + + +TW + + + I +++ +
Sbjct 259 ASASDLDVTDTMQFEVKAPRQIKNLTVNPSERDAIVTWESEGGEDMAI---DLRLVRRTD 315
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRP 326
+ + +D S +++DL+ T Y + +++ T + RP
Sbjct 316 TRGQVVFSKDNL--TSPVSIKDLRAATPYTLFVSGNNGQVPFEFTE-----HFTTKQKRP 368
Query 327 SKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT--------------- 371
P + ++ + ++ WK P E NG+I Y V++
Sbjct 369 F--PPKEEDVRVLNSGSALSCEVEWK--SPAEPNGRITKYFVSVRGAMRKSDGSLTPDDL 424
Query 372 -----------RWKSHLQNYTVNA------------TKLTVNLTNDRYLATLTVRNLVGK 408
W N K N Y T+ N G+
Sbjct 425 PAAVEVDKRCANWDGDENTSKHNGINPIDFANEFYSCKFGPLKPNRNYTVTVWAENSAGR 484
Query 409 SDAAVLTIPACDFQATHPVMDLKAFP----KDNMLWVEWTTPRESVKKYILEWCVLSDKA 464
S AV C P M P + + + P + + I + +
Sbjct 485 SLPAVF-HKNCVTNYAQPDMVETPQPLLSNNHSTFSLTFPQPPDDINGPISCYYIAIVPL 543
Query 465 PC------ITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP 504
P + ++ NL S A+
Sbjct 544 PANVSLDILPKSEEIVMHSFSKVFTNNLLPSSAEEKRFFAYIAESY 589
Score = 60.6 bits (145), Expect = 7e-08, Method: Composition-based stats.
Identities = 65/435 (15%), Positives = 126/435 (29%), Gaps = 66/435 (15%)
Query 34 ESPVVQLHSNFT-AVCVLKEKCMDYFHVNANYIVWKTNHFTI---------PKEQYTIIN 83
S V + T C+ ++ + + N + P+
Sbjct 175 PSTSVSKGIDVTLFCCI---NVDPEGFIDVASVFFIQNGTIMREATSHPFAPRNGLARRV 231
Query 84 RTASSVTFTDIASLNIQLTCNILT-FGQLEQNVYGITI--ISGLPPEKPKNLSCIVNEGK 140
S +I + + + + ++ P + KNL+ +E
Sbjct 232 HEKYSCWELEIKNAQTSDSGSYMCRVTASASDLDVTDTMQFEVKAPRQIKNLTVNPSERD 291
Query 141 KMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEA 200
+ W+ E + L+ T +D TS ++V
Sbjct 292 AIV-TWE--SEGGEDMAIDLRLVRRTDTRGQVVFSKDNLTSPVSIKDLRAATPYTLFVSG 348
Query 201 ENALGKVTSDHINFDPVYKVKPNPP--HNLSVINSEELSSILKLTWTNPSIKSVIILKYN 258
N G+V + + +P PP ++ V+NS S ++ W +P+ + I KY
Sbjct 349 NN--GQVPFEFTEHFTTKQKRPFPPKEEDVRVLNSGSALSC-EVEWKSPAEPNGRITKYF 405
Query 259 IQYRT------------------------------KDASTWSQIPPEDTASTRSSFTVQD 288
+ R ++ S + I P D A+ S
Sbjct 406 VSVRGAMRKSDGSLTPDDLPAAVEVDKRCANWDGDENTSKHNGINPIDFANEFYSCKFGP 465
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
LKP Y + G+ S A P P + + T
Sbjct 466 LKPNRNYTVTVWAENSAGR------SLPAVFHKNCVTNYAQPDMVETPQPLLSNNHSTFS 519
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK 408
L + PP + NG I Y + + +++ + ++ V + + N +
Sbjct 520 LTF-PQPPDDINGPISCYYIAIVPLPANVSLDILPKSEEIV-----MHSFSKVFTNNLLP 573
Query 409 SDAAVLTIPACDFQA 423
S A A ++
Sbjct 574 SSAEEKRFFAYIAES 588
Score = 60.6 bits (145), Expect = 7e-08, Method: Composition-based stats.
Identities = 40/278 (14%), Positives = 69/278 (25%), Gaps = 53/278 (19%)
Query 360 NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPAC 419
NG + W+ ++N + + Y+ +T SD V
Sbjct 225 NGLARRVHEKYSCWELEIKNAQTSDS--------GSYMCRVTA----SASDLDVTDTMQF 272
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
+ +A + +L P + V W + L L + +
Sbjct 273 EVKAPRQIKNLTVNPSERDAIVTWESEGGEDMAIDL---RLVRRTDTRGQVVFSKDNLTS 329
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP-PSKGPTVRTKKVGKN-EAVL 537
+L + Y + V+ P ++ P P K VR G +
Sbjct 330 PVSIKDLRAATPYTLFVSGNNGQVPFEFTEHFTTKQKRPFPPKEEDVRVLNSGSALSCEV 389
Query 538 EWDQLPVDVQNGFIRNYTIFYR-----------------TIIGNETAVNVDSSHT----- 575
EW NG I Y + R + ++ N D
Sbjct 390 EWKS--PAEPNGRITKYFVSVRGAMRKSDGSLTPDDLPAAVEVDKRCANWDGDENTSKHN 447
Query 576 ------------EYTLSSLTSDTLYMVRMAAYTDEGGK 601
L + Y V + A G
Sbjct 448 GINPIDFANEFYSCKFGPLKPNRNYTVTVWAENSAGRS 485
Score = 57.6 bits (137), Expect = 6e-07, Method: Composition-based stats.
Identities = 50/321 (16%), Positives = 90/321 (28%), Gaps = 56/321 (17%)
Query 337 DPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN-ATKLTVNLTNDR 395
+ + R + W++ + I V T + + N + +++
Sbjct 282 NLTVNPSERDAIVTWESEGGEDM--AIDLRLVRRTDTRGQVVFSKDNLTSPVSIKDLRAA 339
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPV--MDLKAFPKDNML--WVEWTTPRESVK 451
TL V G+ + P D++ + L VEW +P E
Sbjct 340 TPYTLFVSGNNGQVPFEFTEHFTTKQKRPFPPKEEDVRVLNSGSALSCEVEWKSPAEP-N 398
Query 452 KYILEWCVLSDKAPCITD--------------------WQQEDGTVH------------- 478
I ++ V A +D W ++ T
Sbjct 399 GRITKYFVSVRGAMRKSDGSLTPDDLPAAVEVDKRCANWDGDENTSKHNGINPIDFANEF 458
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPES-----IKAYLKQAPPSKGPTVRTKKVGKN 533
+ G L ++ Y +TV + G P + Y + + +
Sbjct 459 YSCKFGPLKPNRNYTVTVWAENSAGRSLPAVFHKNCVTNYAQPDMVETPQPLLSNNHSTF 518
Query 534 EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN-------ETAVNVDSSHTEYTLSSLTSDT 586
P D NG I Y I + N ++ V S ++ ++L +
Sbjct 519 SLTF---PQPPDDINGPISCYYIAIVPLPANVSLDILPKSEEIVMHSFSKVFTNNLLPSS 575
Query 587 LYMVRMAAYTDEGGKDGPEFT 607
R AY E PE T
Sbjct 576 AEEKRFFAYIAESYVQLPEET 596
>sp|P09208|INSR_DROME Insulin-like receptor OS=Drosophila melanogaster
OX=7227 GN=InR PE=1 SV=3
Length=2144
Score = 63.0 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 32/201 (16%), Positives = 65/201 (32%), Gaps = 28/201 (14%)
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP--------------ESIKAYLKQ 516
++ + L Y I V + P +++ K+
Sbjct 1142 KELPPNQTHF-VFEKLRHFTRYAIFVVACREEIPSEKLRDTSFKKSLCSDYDTVFQTTKR 1200
Query 517 APPSKGP-----TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN--ETAVN 569
+ + ++ + W P NG I Y + Y+ + E
Sbjct 1201 KKFADIVMDLKVDLEHANNTESPVRVRW--TPPVDPNGEIVTYEVAYKLQKPDQVEEKKC 1258
Query 570 VDSSHTEYTLSSLTS--DTLYMVRMAAYTDEGGKDGPEFTF--TTPKFAQGEIEAIVVPV 625
+ ++ T L + LY R+ A + G D E P + ++ ++ +
Sbjct 1259 IPAADFNQTAGYLIKLNEGLYSFRVRANSIAGYGDFTEVEHIKVEPPPSYAKVFFWLLGI 1318
Query 626 CLAFLLTTLLGVLFCFNKRDL 646
LAFL+ +L G + +KR +
Sbjct 1319 GLAFLIVSLFGYVCYLHKRKV 1339
Score = 57.6 bits (137), Expect = 7e-07, Method: Composition-based stats.
Identities = 24/158 (15%), Positives = 46/158 (29%), Gaps = 14/158 (9%)
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILE-WCVL--S 461
VG + A + + + KD ++ V ++++ + S
Sbjct 815 SVGANSAMLNVTTKVEIGEPQKPSNATIVFKDPRAFI------GFVFYHMIDPYGNSTKS 868
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT--PVYAD-GPGSPESIKAYLKQAP 518
PC W+ + NL Y V + ++ +
Sbjct 869 SDDPCDDRWKVSSPEKSGVMVLSNLIPYTNYSYYVRTMAISSELTNAESDVKNFRTNPGR 928
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
PSK V + ++ + W L D G + Y I
Sbjct 929 PSKVTEVVATAISDSKINVTWSYL--DKPYGVLTRYFI 964
Score = 54.5 bits (129), Expect = 5e-06, Method: Composition-based stats.
Identities = 20/101 (20%), Positives = 39/101 (39%), Gaps = 6/101 (6%)
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS-TRSSFTV 286
+ + ++ S +++ WT P + I+ Y + Y+ + + A +++ +
Sbjct 1212 VDLEHANNTESPVRVRWTPPVDPNGEIVTYEVAYKLQKPDQVEEKKCIPAADFNQTAGYL 1271
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
L Y FR+R G G + E I E PS
Sbjct 1272 IKLNEG-LYSFRVRANSIAGYGDF----TEVEHIKVEPPPS 1307
Score = 51.4 bits (121), Expect = 5e-05, Method: Composition-based stats.
Identities = 26/172 (15%), Positives = 51/172 (30%), Gaps = 22/172 (13%)
Query 271 QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM-----------KEDGKGYWSDWSEEASG 319
++ ++ ++ F + L+ FT Y + K SD+ +
Sbjct 1138 EVFAKELPPNQTHFVFEKLRHFTRYAIFVVACREEIPSEKLRDTSFKKSLCSDY-DTVFQ 1196
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT-------R 372
T + + V++ W PP + NG+I+ YEV
Sbjct 1197 TTKRKKFADIVMDLKVDLEHANNTESPVRVRW--TPPVDPNGEIVTYEVAYKLQKPDQVE 1254
Query 373 WKSHLQNYTVNATK-LTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA 423
K + N T + L Y + ++ G D + +
Sbjct 1255 EKKCIPAADFNQTAGYLIKLNEGLYSFRVRANSIAGYGDFTEVEHIKVEPPP 1306
>sp|Q6WG24|IL4RA_HORSE Interleukin-4 receptor subunit alpha OS=Equus
caballus OX=9796 GN=IL4R PE=2 SV=2
Length=809
Score = 62.6 bits (150), Expect = 1e-08, Method: Composition-based stats.
Identities = 48/202 (24%), Positives = 74/202 (37%), Gaps = 17/202 (8%)
Query 134 CIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFAD---CKAKRDTPTSCTVDYSTVY 190
C + CEW R T+ L + +F+D C + C
Sbjct 34 CFSDYISASTCEWKMDRPTNCSAQLRLSYQL-NDEFSDNLTCIPENREDEVCVCRMLMDN 92
Query 191 FVN---IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP 247
V+ E+ + A N L +S F P VKP P NL+V LTW+NP
Sbjct 93 IVSEDVYELDLWAGNQLLWNSS----FKPSRHVKPRAPQNLTVHAISHTWL---LTWSNP 145
Query 248 -SIKSVI--ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+K+ + L Y + +D T +I T LK Y R++ +
Sbjct 146 YPLKNHLWSELTYLVNISKEDDPTDFKIYNVTYMDPTLRVTASTLKSRATYSARVKARAQ 205
Query 305 DGKGYWSDWSEEASGITYEDRP 326
+ WS+WS + Y ++P
Sbjct 206 NYNSTWSEWSPSTTWHNYYEQP 227
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 30/201 (15%), Positives = 55/201 (27%), Gaps = 17/201 (8%)
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKV 530
+ED L N+ Y + + S + P + +
Sbjct 78 NREDEVCVCRMLMDNIVSEDVYELDLWAGN---QLLWNSSFKPSRHVKPRAPQNLTVHAI 134
Query 531 GKNEAVLEWDQLPVDVQN--GFIRNYTIFY-RTIIGNETAV---NVDSSHTEYTLSSLTS 584
L W + + Y + + + + T S+L S
Sbjct 135 SHTWL-LTWSNPYPLKNHLWSELT-YLVNISKEDDPTDFKIYNVTYMDPTLRVTASTLKS 192
Query 585 DTLYMVRMAA----YTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFC 640
Y R+ A Y + P T+ E + ++ + L C
Sbjct 193 RATYSARVKARAQNYNSTWSEWSPSTTWHNYYEQPLEQRLPLGVSISCVVILAI--CLSC 250
Query 641 FNKRDLIKKHIWPNVPDPSKS 661
+ IKK W +P+P+ S
Sbjct 251 YFSIIKIKKEWWDQIPNPAHS 271
>sp|B4N072|IHOG_DROWI Interference hedgehog OS=Drosophila willistoni
OX=7260 GN=iHog PE=3 SV=1
Length=881
Score = 62.6 bits (150), Expect = 1e-08, Method: Composition-based stats.
Identities = 44/284 (15%), Positives = 95/284 (33%), Gaps = 36/284 (13%)
Query 359 ANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPA 418
+NG+ L + L ++Q + N T + L + S
Sbjct 387 SNGRYLVLKKVLKEHAGYVQCFARNHLGEHSAGTLLQVNPKLVNETDLVVSRPQRPKKLQ 446
Query 419 CDFQATHPVMDLKAFPKDNMLWVEWTTPRE---SVKKYILEWCVLSDKAPCITDWQQEDG 475
+ P + + D + + W R ++ + +++ ++++ + WQ +
Sbjct 447 IMVPPSAPNVTRLS---DESVMLRWHVQRNEGLPIQFFKVQYRLINEGKRKM--WQTTNE 501
Query 476 TVHR-------------TYLRGNLAESKCYLITVTPV--YADGPGSPESIKAYLKQAP-- 518
+ T NL + Y + V D S S K +L++
Sbjct 502 NIPYGKPKWNSALGKNFTASVTNLKPQRTYRFRIMAVYSNNDNKESNTSAKFFLQRGSSL 561
Query 519 -PSKGPT-VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVD-SS 573
P P V+ + + VL W L D I Y +YR G + ++ +
Sbjct 562 EPMPVPELVKIDEYSETAVVLHWR-LSDDADEQSITGYYAYYRPSSFAGEYSKATIEGAK 620
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
+ + SL T+Y ++ +++ + F+ K + +
Sbjct 621 ARSFHIGSLEVGTIYEFKLQSFSAD-----SASEFSALKQGRTQ 659
Score = 57.9 bits (138), Expect = 4e-07, Method: Composition-based stats.
Identities = 41/248 (17%), Positives = 74/248 (30%), Gaps = 39/248 (16%)
Query 155 ETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS----- 209
T + L + +H+ + + + V A N LG+ ++
Sbjct 366 PTIYWLLNGKRSHEVNQSQLLSNGRY-LVLKKVLKEHAGY-VQCFARNHLGEHSAGTLLQ 423
Query 210 -DHINFDPVYKVKPNP--PHNLSVINSEELSSILKLT-------WTNPSIKSVIILKYNI 259
+ + V P P L ++ ++ +L+ W + + I + +
Sbjct 424 VNPKLVNETDLVVSRPQRPKKLQIMVPPSAPNVTRLSDESVMLRWHVQRNEGLPIQFFKV 483
Query 260 QYRTKDAS---TWSQIPPE---------DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
QYR + W + +V +LKP Y FRI + +
Sbjct 484 QYRLINEGKRKMWQTTNENIPYGKPKWNSALGKNFTASVTNLKPQRTYRFRIMAVYSNND 543
Query 308 GYWSDWSEE---ASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKIL 364
S+ S + G + E P P + S T V L W+ L I
Sbjct 544 NKESNTSAKFFLQRGSSLE--PMPVPELVKIDEYSET----AVVLHWR-LSDDADEQSIT 596
Query 365 DYEVTLTR 372
Y
Sbjct 597 GYYAYYRP 604
>sp|Q8IWZ5|TRI42_HUMAN Tripartite motif-containing protein 42
OS=Homo sapiens OX=9606 GN=TRIM42 PE=1 SV=2
Length=723
Score = 62.2 bits (149), Expect = 2e-08, Method: Composition-based stats.
Identities = 24/127 (19%), Positives = 49/127 (39%), Gaps = 14/127 (11%)
Query 194 IEVWVEAENALGKVTSDHIN----FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
W ++ S + F+ P P + + + K+ WT P+
Sbjct 572 YTYWSAGADSQSVQNSSSFHNWYSFNDGSVKTPGP---IVIYQTLVYPRAAKVYWTCPAE 628
Query 250 KSVIILKYNIQYRTKDASTWSQIPPEDT----ASTRSSFTVQDLKPFTEYVFRIRCMKED 305
+ + +++ S + + E + + + +L P TEYVF++R + ++
Sbjct 629 ---DVDSFEMEFYEVITSPPNNVQMELCGQIRDIMQQNLELHNLTPNTEYVFKVRAINDN 685
Query 306 GKGYWSD 312
G G WSD
Sbjct 686 GPGQWSD 692
Score = 39.8 bits (91), Expect = 0.12, Method: Composition-based stats.
Identities = 19/90 (21%), Positives = 31/90 (34%), Gaps = 5/90 (6%)
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW----QQEDG 475
+ P++ + V WT P E V + +E+ + P Q D
Sbjct 600 SVKTPGPIVIYQTLVYPRAAKVYWTCPAEDVDSFEMEFYEVITSPPNNVQMELCGQIRDI 659
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPG 505
L NL + Y+ V + +GPG
Sbjct 660 MQQNLELH-NLTPNTEYVFKVRAINDNGPG 688
>sp|Q5PQM4|MBPHL_RAT Myosin-binding protein H-like OS=Rattus norvegicus
OX=10116 GN=Mybphl PE=1 SV=1
Length=355
Score = 61.0 bits (146), Expect = 2e-08, Method: Composition-based stats.
Identities = 22/95 (23%), Positives = 39/95 (41%), Gaps = 6/95 (6%)
Query 213 NFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTKDASTWSQ 271
+ + KP PP ++ +++ ++ L WT P + +L Y +Q K + W
Sbjct 138 TINILVIEKPGPPQSIKLVDVWGANA--TLEWTPPQDTGNTALLGYTVQKADKKSGLWFT 195
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ R+S V DL Y FR+ + G
Sbjct 196 VLERY---HRTSCIVSDLIVGNSYAFRVFAENQCG 227
Score = 55.6 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 29/168 (17%), Positives = 53/168 (32%), Gaps = 7/168 (4%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLE-QN 114
+ +W N + + ++ N S+ F + C L Q
Sbjct 77 PFQGKPKPQTIWTHNGSALDNSRVSVRNGEHDSILFIR-EAQRTDSGCYQLCVQLGGLQA 135
Query 115 VYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN---FTLKSEWATHKFAD 171
I I+ P P+++ + G EW ++T T +T++
Sbjct 136 TATINILVIEKPGPPQSIKLVDVWGANATLEWTPPQDTG-NTALLGYTVQKADKKSGLWF 194
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYK 219
+R TSC V + + V AEN G + + D +
Sbjct 195 TVLERYHRTSCIVS-DLIVGNSYAFRVFAENQCGLSDTAPVTADLAHI 241
Score = 39.8 bits (91), Expect = 0.10, Method: Composition-based stats.
Identities = 17/109 (16%), Positives = 31/109 (28%), Gaps = 1/109 (1%)
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPK-DNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
A TI + P +K +EWT P+++ +L + V
Sbjct 132 GLQATATINILVIEKPGPPQSIKLVDVWGANATLEWTPPQDTGNTALLGYTVQKADKKSG 191
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ + + + +L Y V G + A L
Sbjct 192 LWFTVLERYHRTSCIVSDLIVGNSYAFRVFAENQCGLSDTAPVTADLAH 240
>sp|Q9D968|HCFC2_MOUSE Host cell factor 2 OS=Mus musculus OX=10090
GN=Hcfc2 PE=1 SV=2
Length=722
Score = 61.8 bits (148), Expect = 2e-08, Method: Composition-based stats.
Identities = 37/268 (14%), Positives = 77/268 (29%), Gaps = 28/268 (10%)
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
+ + + + + L N +N+ T +R A+ +
Sbjct 443 VRGTSLRSKPDSRAVDSSAALHSPLAPNTSNNSSWVTDMLRKNEVDEICALPATKISRVE 502
Query 423 ATHPVMDLKAFPKDNMLWV----EWTTPR--ESVKKYILEWCVLSDKAPCITDWQQEDGT 476
N + + +W ++ + ++ +L ++ D
Sbjct 503 VHAAATPFSKETPSNPVAILKAEQWCDVGIFKNNTALVSQFYLLPKGKQSMSKVGNADVP 562
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP--PSKGPTVRTKKVGKNE 534
+ + +L Y V + G G + + P P TVR K +
Sbjct 563 DYSLLKKQDLVPGTVYKFRVAAINGCGIGPLSKVSEFKTCTPGFPGAPSTVRISK-NVDG 621
Query 535 AVLEWDQLPVDVQNGFIRNY-----------------TIFYRTIIGNETAVNVDSSHTEY 577
L W+ P +G I Y +F R G +T+ V +
Sbjct 622 IHLSWE--PPTSPSGNILEYSAYLAIRTAQMQDNPSQLVFMRIYCGLKTSCTVTAGQLAN 679
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
TS + R++A ++G +
Sbjct 680 AHIDYTSRPAIVFRISAKNEKGYGPATQ 707
Score = 56.8 bits (135), Expect = 9e-07, Method: Composition-based stats.
Identities = 34/161 (21%), Positives = 53/161 (33%), Gaps = 31/161 (19%)
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
QDL P T Y FR+ + G G S SE + P APS ++
Sbjct 570 QDLVPGTVYKFRVAAINGCGIGPLSKVSEFKTCTP--GFP-GAPSTVRI-----SKNVDG 621
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA----------TKLTV------- 389
+ L W+ PP +G IL+Y L + +Q+ T TV
Sbjct 622 IHLSWE--PPTSPSGNILEYSAYLAIRTAQMQDNPSQLVFMRIYCGLKTSCTVTAGQLAN 679
Query 390 ----NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHP 426
+ + ++ +N G A + + P
Sbjct 680 AHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQDQEKDVGP 720
Score = 51.8 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 26/132 (20%), Positives = 44/132 (33%), Gaps = 17/132 (13%)
Query 192 VNIEVWVEAENALGKVTSDHIN-FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+ V A N G ++ F P P + + + + + L+W P+
Sbjct 576 TVYKFRVAAINGCGIGPLSKVSEFKTCTPGFPGAPSTVRISKNVDG---IHLSWEPPTSP 632
Query 251 SVIILKYN----IQYRTKDASTWSQIPPEDTASTRSSFTVQD---LKPFTEY------VF 297
S IL+Y+ I+ + + ++S TV +Y VF
Sbjct 633 SGNILEYSAYLAIRTAQMQDNPSQLVFMRIYCGLKTSCTVTAGQLANAHIDYTSRPAIVF 692
Query 298 RIRCMKEDGKGY 309
RI E G G
Sbjct 693 RISAKNEKGYGP 704
Score = 42.2 bits (97), Expect = 0.025, Method: Composition-based stats.
Identities = 19/138 (14%), Positives = 35/138 (25%), Gaps = 18/138 (13%)
Query 391 LTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES 449
+ Y + N G + V C ++ + + + W P
Sbjct 573 VPGTVYKFRVAAINGCGIGPLSKVSEFKTCTPGFPGAPSTVRISKNVDGIHLSWEPPTSP 632
Query 450 VKKYILEW--------CVLSDKAPCITDWQQEDGTVHR-TYLRGNLA-ESKCYL------ 493
ILE+ + D + + G T G LA Y
Sbjct 633 SGN-ILEYSAYLAIRTAQMQDNPSQLVFMRIYCGLKTSCTVTAGQLANAHIDYTSRPAIV 691
Query 494 ITVTPVYADGPGSPESIK 511
++ G G ++
Sbjct 692 FRISAKNEKGYGPATQVR 709
>sp|Q28938|IL12B_PIG Interleukin-12 subunit beta OS=Sus scrofa
OX=9823 GN=IL12B PE=2 SV=1
Length=324
Score = 59.9 bits (143), Expect = 3e-08, Method: Composition-based stats.
Identities = 45/238 (19%), Positives = 87/238 (37%), Gaps = 37/238 (16%)
Query 99 IQLTCNILTFGQLEQNVYGITIISGLPPEKPKN---LSCIV-NEGKKMRCEW-------- 146
L+ ++L + E ++ I+ ++PKN L C N + C W
Sbjct 95 AVLSQSLLLLHKKEDGIWSTDILKDQ--KEPKNKSFLKCEAKNYSGRFTCWWLTAISTDL 152
Query 147 -------DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVE 199
G + T T ++ + + ++C ++ IEV +E
Sbjct 153 KFSVKSSRGSTDPRGVTCGTATLSEDLGEYKKYRVECQEGSACPAAEESL---PIEVVLE 209
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP----SIKSVIIL 255
A + L K + +F +KP+PP NL + N + S ++++W P + S L
Sbjct 210 AVHKL-KYENYTSSFFIRDIIKPDPPKNLQL-NPLKNSRHVEISWEYPDTWSTPHSYFSL 267
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ +Q + K+ D S + + +D R++ WS+W
Sbjct 268 MFGVQVQGKNKREKKDKLFTDQISAKVTCH-KDAN------IRVQARDRYYSSSWSEW 318
>sp|Q5FW53|MBPHL_MOUSE Myosin-binding protein H-like OS=Mus musculus
OX=10090 GN=Mybphl PE=1 SV=1
Length=355
Score = 60.3 bits (144), Expect = 4e-08, Method: Composition-based stats.
Identities = 21/95 (22%), Positives = 39/95 (41%), Gaps = 6/95 (6%)
Query 213 NFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTKDASTWSQ 271
+ + KP PP ++ +++ ++ L WT P + +L Y +Q K + W
Sbjct 138 TINILVIEKPGPPQSIKLVDVWGANA--TLEWTPPQDTGNTALLGYTVQKADKKSGLWFT 195
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ R+S V +L Y FR+ + G
Sbjct 196 VLERY---HRTSCVVSNLIVGNSYAFRVFAENQCG 227
Score = 53.7 bits (127), Expect = 4e-06, Method: Composition-based stats.
Identities = 29/168 (17%), Positives = 52/168 (31%), Gaps = 7/168 (4%)
Query 56 DYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLE-QN 114
W N + + ++ N S+ F + C L Q
Sbjct 77 PIQGKPKPQTTWTHNGCALDSSRVSVRNGEHDSILFIR-EAQRTDSGCYQLCVQLGGLQA 135
Query 115 VYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETN---FTLKSEWATHKFAD 171
I I+ P P+++ + G EW ++T T +T++
Sbjct 136 TATINILVIEKPGPPQSIKLVDVWGANATLEWTPPQDTG-NTALLGYTVQKADKKSGLWF 194
Query 172 CKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYK 219
+R TSC V + + + V AEN G + + D +
Sbjct 195 TVLERYHRTSCVVS-NLIVGNSYAFRVFAENQCGLSDTAPVTADLAHI 241
Score = 47.2 bits (110), Expect = 5e-04, Method: Composition-based stats.
Identities = 36/178 (20%), Positives = 53/178 (30%), Gaps = 21/178 (12%)
Query 491 CYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGF 550
CY + V G + +I + + P +++ V A LEW P D N
Sbjct 123 CYQLCVQ---LGGLQATATINILVIEK-PGPPQSIKLVDVWGANATLEWTP-PQDTGNTA 177
Query 551 IRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT 609
+ YT+ G V T +S+L Y R+ A G D T
Sbjct 178 LLGYTVQKADKKSGLWFTVLERYHRTSCVVSNLIVGNSYAFRVFAENQCGLSDTAPVTAD 237
Query 610 TPKFAQ---------------GEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIW 652
+ E P+ +T LFC + K IW
Sbjct 238 LAHIQKAATVYKAKGFAQRDLSEAPKFTQPLADCTTVTGYDTQLFCCVRASPRPKIIW 295
Score = 40.2 bits (92), Expect = 0.081, Method: Composition-based stats.
Identities = 18/109 (17%), Positives = 31/109 (28%), Gaps = 1/109 (1%)
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPK-DNMLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
A TI + P +K +EWT P+++ +L + V
Sbjct 132 GLQATATINILVIEKPGPPQSIKLVDVWGANATLEWTPPQDTGNTALLGYTVQKADKKSG 191
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ + + + NL Y V G + A L
Sbjct 192 LWFTVLERYHRTSCVVSNLIVGNSYAFRVFAENQCGLSDTAPVTADLAH 240
>sp|Q863Z5|IL4RA_PIG Interleukin-4 receptor subunit alpha OS=Sus
scrofa OX=9823 GN=IL4R PE=2 SV=1
Length=830
Score = 61.0 bits (146), Expect = 4e-08, Method: Composition-based stats.
Identities = 43/202 (21%), Positives = 68/202 (34%), Gaps = 15/202 (7%)
Query 134 CIVNEGKKMRCEWDGGRETHLETNFTLKSEWA---THKFADCKAKRDTPTSCTVDYSTVY 190
C+ + CEW + F L + T C + + C
Sbjct 41 CLSDYVSTSTCEWRMAGPVNCSAEFRLSYQLKFFNTENHTTCVPENRAGSVCVCHMLMES 100
Query 191 FV---NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP 247
V ++ + A L +S F P VKP P NL V ++ + L LTW+NP
Sbjct 101 IVIVDTYQLDLWAGEQLLWNSS----FKPSQNVKPLAPRNLMV-HANISHTWL-LTWSNP 154
Query 248 SIKSVII---LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ L Y + ++ T +I F LK Y R++ +
Sbjct 155 YPSESYLYSELTYLVNISNENDPTDFRIYNVTYLGPTLRFPANTLKSGAAYSARVKAWAQ 214
Query 305 DGKGYWSDWSEEASGITYEDRP 326
WS+WS + Y + P
Sbjct 215 RYNSTWSEWSPSVKWLNYYEEP 236
Score = 44.1 bits (102), Expect = 0.007, Method: Composition-based stats.
Identities = 22/153 (14%), Positives = 46/153 (30%), Gaps = 13/153 (8%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDV--QNGFIRNYTIFYRTIIGNET----AVNVDS 572
P + + +L W + Y + V
Sbjct 131 PLAPRNLMVHANISHTWLLTWSNPYPSESYLYSELT-YLVNISNENDPTDFRIYNVTYLG 189
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIV---VPVCLAF 629
+ ++L S Y R+ A+ + ++ E + +P+ ++
Sbjct 190 PTLRFPANTLKSGAAYSARVKAW--AQRYNSTWSEWSPSVKWLNYYEEPLEQRLPLGVSI 247
Query 630 LLTTLLGV-LFCFNKRDLIKKHIWPNVPDPSKS 661
+L + L C+ IKK W +P+P+ S
Sbjct 248 SCVVILIICLSCYFGIIRIKKEWWDQIPNPAHS 280
>sp|P32927|IL3RB_HUMAN Cytokine receptor common subunit beta OS=Homo
sapiens OX=9606 GN=CSF2RB PE=1 SV=2
Length=897
Score = 61.0 bits (146), Expect = 5e-08, Method: Composition-based stats.
Identities = 46/213 (22%), Positives = 70/213 (33%), Gaps = 25/213 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKS----EWATHKFADCKAK-----RD 177
+P+NL C + + C W+ +E +F L + + + +
Sbjct 243 AQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSLHT 302
Query 178 TPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELS 237
V V+ A + S P +L+V +
Sbjct 303 RHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSS--------VNIQMAPPSLNVTKDGDSY 354
Query 238 SILKLTWTNPSIKSVIIL-KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
S L W ++ I + IQYR KD +TW E T S + L+P T Y
Sbjct 355 S---LRWETMKMRYEHIDHTFEIQYR-KDTATWKDSKTE-TLQNAHSMALPALEPSTRYW 409
Query 297 FRIRCMKED--GKGYWSDWSEEASGITYEDRPS 327
R+R G WS+WSE S T P
Sbjct 410 ARVRVRTSRTGYNGIWSEWSEARSWDTESVLPM 442
Score = 59.5 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 77/498 (15%), Positives = 154/498 (31%), Gaps = 60/498 (12%)
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI-LDYEVTLTRWKSHL 377
+T +P + D H +V L P L++EV R +
Sbjct 126 TLTQHVQPPEPRDLQISTDQDHFLLTWSVAL---GSPQSHWLSPGDLEFEVVYKRLQDSW 182
Query 378 QNYTV---NATKLTVNL----TNDRYLATLTVRNLVGK------SDAAVLTIPACDFQAT 424
++ + N ++ T+ + Y+A + R G S +
Sbjct 183 EDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPGDE 242
Query 425 HPVMDLKAF-PKDNMLWVEWTTPRE--SVKKYILEWCVLSD-KAPCITDWQQEDGTVHRT 480
+L+ F +L W +E S + L + D + +E T
Sbjct 243 AQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSLHT 302
Query 481 YLRGNL-----AESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
+ A Y+++V P A+ ++ APPS +
Sbjct 303 RHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSS---VNIQMAPPSLN-----VTKDGDSY 354
Query 536 VLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT--LSSLTSDTLYMVRMA 593
L W+ + + ++ + I YR ++ ++ L +L T Y R+
Sbjct 355 SLRWETMKMRYEHIDHT-FEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVR 413
Query 594 AYTDEGGKDGPEFTFTTPKFAQGE-------IEAIVVPVCLAFLLTTLLGVLFCFNKRDL 646
T G +G ++ + E + IV+ + +A LL ++ + R
Sbjct 414 VRTSRTGYNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLALRFCGIYGYRLR-- 471
Query 647 IKKHIWPNVPDPSKSHIAQ------WSPHTPPRHNFNSKD-QMYSDGNFTDVS---VVEI 696
+ +P+PSKSH+ Q W P + S Q F ++ V
Sbjct 472 --RKWEEKIPNPSKSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGF 529
Query 697 EANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSST 756
++ P + +T +S + S ++S E ++
Sbjct 530 GDSEVSPLTIEDPKHVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFD- 588
Query 757 VQYSTVVHSGYRHQVPSV 774
+ + +P +
Sbjct 589 -FNGPYLGPPHSRSLPDI 605
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 38/211 (18%), Positives = 74/211 (35%), Gaps = 31/211 (15%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATH-------------KFADCKAKR 176
+ L C + + C W ++ N TL ++ C R
Sbjct 31 QTLRCYNDYTSHITCRWADTQDAQRLVNVTLIRRVNEDLLEPVSCDLSDDMPWSACPHPR 90
Query 177 DTPTSCTVDYSTVYFVNIE-VWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
P C + + +++ + + LG + V+P P +L + ++
Sbjct 91 CVPRRCVIPCQSFVVTDVDYFSFQPDRPLG----TRLTVTLTQHVQPPEPRDLQISTDQD 146
Query 236 LSSILKLTWTN--PSIKSVII----LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDL 289
LTW+ S +S + L++ + Y+ S W + +++++ + L
Sbjct 147 H---FLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQDS-WEDAAILLSNTSQATLGPEHL 202
Query 290 KPFTEYVFRIRCMKEDG---KGYWSDWSEEA 317
P + YV R+R G G S WS E
Sbjct 203 MPSSTYVARVRTRLAPGSRLSGRPSKWSPEV 233
>sp|Q5VST9|OBSCN_HUMAN Obscurin OS=Homo sapiens OX=9606 GN=OBSCN
PE=1 SV=3
Length=7968
Score = 61.4 bits (147), Expect = 5e-08, Method: Composition-based stats.
Identities = 20/99 (20%), Positives = 34/99 (34%), Gaps = 6/99 (6%)
Query 213 NFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQ 271
+ P+PP + V+ S + L+W P S + Y ++ + W +
Sbjct 4514 SARLTVLGLPDPPEDAEVVAR--SSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQW-R 4570
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
+ E V L P Y FR+ + G G
Sbjct 4571 LCHELVPGP--ECVVDGLAPGETYRFRVAAVGPVGAGEP 4607
Score = 51.0 bits (120), Expect = 6e-05, Method: Composition-based stats.
Identities = 31/216 (14%), Positives = 55/216 (25%), Gaps = 18/216 (8%)
Query 391 LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW---VEWTTPR 447
D T ++V +A LT+ + P+ + + + P
Sbjct 4405 RPQDSCRVTFLAGDMV---TSAFLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPV 4461
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
YI V P +DW H L + +T +
Sbjct 4462 GEASWYINGAAV----QPDDSDWTVTADGSHHALLLRSAQPHHAGEVT-FACRDAVASAR 4516
Query 508 ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT-IIGNET 566
++ P + L W P+ G + Y + + G
Sbjct 4517 LTVLG-----LPDPPEDAEVVARSSHTVTLSW-AAPMSDGGGGLCGYRVEVKEGATGQWR 4570
Query 567 AVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ E + L Y R+AA G +
Sbjct 4571 LCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGE 4606
Score = 50.6 bits (119), Expect = 9e-05, Method: Composition-based stats.
Identities = 33/180 (18%), Positives = 60/180 (33%), Gaps = 23/180 (13%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
NALG VT+ + + +P ++ E + + L W P + Y +
Sbjct 7538 VSNALGTVTTTGV-LRKAERPSSSPCPDIG----EVYADGVLLVWK-PVESYGPVT-YIV 7590
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEA-- 317
Q + S W+ + + + L Y FR C+ + G G +S SE+
Sbjct 7591 QCSLEGGS-WTTLASDIFD---CCYLTSKLSRGGTYTFRTACVSKAGMGPYSSPSEQVLL 7646
Query 318 ---SGITYEDR-------PSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE 367
S + E+ P + + + V+ W+ KI+ Y
Sbjct 7647 GGPSHLASEEESQGRSAQPLPSTKTFAFQTQIQRGRFSVVRQCWEKASGRALAAKIIPYH 7706
Score = 49.1 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 21/131 (16%), Positives = 39/131 (30%), Gaps = 20/131 (15%)
Query 498 PVYADGPGSPESIKAYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
A + + PP + P K ++ +L W P + I Y +
Sbjct 491 AFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLV 550
Query 557 F------YRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD-------- 602
Y I +E + E T++ + + + R++A G
Sbjct 551 EKKKLGTYTWIRCHEAEW---VATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTV 607
Query 603 --GPEFTFTTP 611
P+ TP
Sbjct 608 HLAPKLAVRTP 618
Score = 49.1 bits (115), Expect = 3e-04, Method: Composition-based stats.
Identities = 20/105 (19%), Positives = 36/105 (34%), Gaps = 5/105 (5%)
Query 208 TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL--KYNIQYRTKD 265
TS K PP + V + S + L+W+ P + Y ++ +
Sbjct 499 TSTQFCVSAPRKPPLQPPVDPVVKAR--MESSVILSWSPPPHGERPVTIDGYLVEKKKLG 556
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW 310
TW + E TV D+ + FR+ + G+ +
Sbjct 557 TYTWIR-CHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPY 600
Score = 47.5 bits (111), Expect = 6e-04, Method: Composition-based stats.
Identities = 27/161 (17%), Positives = 48/161 (30%), Gaps = 15/161 (9%)
Query 352 KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRY---LATLTVRNLVGK 408
+ +P EA+ I V S + + + + T R+ V
Sbjct 4457 EAVPVGEASWYINGAAV--QPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVAS 4514
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDN-MLWVEWTTPRESVKKYILEWCVLSDKAPCI 467
+ VL +P P D + + + + + W P + + V K
Sbjct 4515 ARLTVLGLPD-------PPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRV-EVKEGAT 4566
Query 468 TDWQQ-EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
W+ + + LA + Y V V G G P
Sbjct 4567 GQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEP 4607
Score = 42.5 bits (98), Expect = 0.025, Method: Composition-based stats.
Identities = 27/171 (16%), Positives = 47/171 (27%), Gaps = 19/171 (11%)
Query 494 ITVTPVYADGPGSPESIKAYLKQA-PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIR 552
+ V + L++A PS P +V + +L W + G +
Sbjct 7531 LGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESY---GPVT 7587
Query 553 NYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK 612
Y + G+ T + D Y S L+ Y R A + G +
Sbjct 7588 -YIVQCSLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGMGPYSSPSEQVLL 7646
Query 613 FAQGEIE---------AIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPN 654
+ A +P F T + R + + W
Sbjct 7647 GGPSHLASEEESQGRSAQPLPSTKTFAFQTQI-----QRGRFSVVRQCWEK 7692
Score = 42.2 bits (97), Expect = 0.032, Method: Composition-based stats.
Identities = 18/127 (14%), Positives = 33/127 (26%), Gaps = 10/127 (8%)
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN 383
P K P + +V L W P E I Y V + ++
Sbjct 506 SAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCHE 565
Query 384 ATKLTVNLT-------NDRYLATLTVRNLVGKSD---AAVLTIPACDFQATHPVMDLKAF 433
A + + ++ N G+S A P+ ++A
Sbjct 566 AEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTPLKAVQAV 625
Query 434 PKDNMLW 440
+ +
Sbjct 626 EGGEVTF 632
Score = 34.1 bits (76), Expect = 8.0, Method: Composition-based stats.
Identities = 51/421 (12%), Positives = 106/421 (25%), Gaps = 72/421 (17%)
Query 38 VQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYT---IINRTASSVTFTDI 94
V+ + C L E W N + + + + ++
Sbjct 4443 VRAGAQACFTCTLSEAVPVGEAS------WYINGAAVQPDDSDWTVTADGSHHALLLRSA 4496
Query 95 ASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHL 154
+ + + + P+ P++ + + W
Sbjct 4497 QPHHAGEVTFACRDAVASARLTVLGL-----PDPPEDAEVVARSSHTVTLSWAAPMSDGG 4551
Query 155 ETN--FTLKSEWA-THKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDH 211
+ ++ + T ++ C P C VD V A +G H
Sbjct 4552 GGLCGYRVEVKEGATGQWRLCHELVPGP-ECVVDGLAPG-ETYRFRVAAVGPVGAGEPVH 4609
Query 212 INFDP-------VYKVKPNPPHNLSVINSEELSSILKLT-------WTNPSIKSVIILKY 257
+ +P+ P + V E++S L++ W + ++
Sbjct 4610 LPQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRF 4669
Query 258 NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK-----PFTEYVFRIRCMKEDGKGYWSD 312
+ + TA + + L P F++ S
Sbjct 4670 EV---VSQGRQQMLVIKGFTAEDQGEYH-CGLAQGSICPAAA-TFQV---------ALSP 4715
Query 313 WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFE--ANGKILDYEVTL 370
S + + PS P + D + L+W+ L + LD L
Sbjct 4716 ASVDEAPQ-----PSLPPEAAQEGD---------LHLLWEALARKRRMSREPTLDSISEL 4761
Query 371 TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
Q A ++ +L+ A R DA + + D +
Sbjct 4762 PEEDGRSQRLPQEAEEVAPDLSEGYSTADELAR----TGDADLSHTSSDDESRAGTPSLV 4817
Query 431 K 431
Sbjct 4818 T 4818
>sp|P26955|IL3RB_MOUSE Cytokine receptor common subunit beta OS=Mus
musculus OX=10090 GN=Csf2rb PE=1 SV=2
Length=896
Score = 60.6 bits (145), Expect = 5e-08, Method: Composition-based stats.
Identities = 39/207 (19%), Positives = 66/207 (32%), Gaps = 25/207 (12%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWA----THKFADCKAKRDT---- 178
+P+NL C + + + C W+ +T +F L + K + +
Sbjct 246 AQPQNLQCFFDGIQSLHCSWEVWTQTTGSVSFGLFYRPSPVAPEEKCSPVVKEPPGASVY 305
Query 179 --PTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEEL 236
V V K ++ PP +N +
Sbjct 306 TRYHCSLPVPEPSAHSQYTVSV-------KHLEQGKFIMSYNHIQMEPPT----LNLTKN 354
Query 237 SSILKLTWTNPSIKSVIIL-KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
L W + I + +QY+ K + +W E+ S + L+P T Y
Sbjct 355 RDSYSLHWETQKMAYSFIEHTFQVQYK-KKSDSWEDSKTENL-DRAHSMDLSQLEPDTSY 412
Query 296 VFRIRCMK-EDGKGYWSDWSEEASGIT 321
R+R + G WS WSEE + T
Sbjct 413 CARVRVKPISNYDGIWSKWSEEYTWKT 439
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 69/433 (16%), Positives = 132/433 (30%), Gaps = 66/433 (15%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRD-------TPTSC 182
K L C + + C W + N TL + + C+ + + C
Sbjct 35 KTLQCYNDYTNHIICSWADTEDAQGLINMTLYHQLEKKQPVSCELSEELMWSECPSSHRC 94
Query 183 TVDYSTVYFVNIEVWVEAENALGKVTSD---HINFDPVYKVKPNPPHNLSVINSEELSSI 239
+ + + E + + SD + V+P P N+S+ +SE+
Sbjct 95 VPRRCVIPYTRFSITNEDYYSF-RPDSDLGIQLMVPLAQNVQPPLPKNVSISSSEDR--- 150
Query 240 LKLTWTNP------SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
L W+ S S +++ + Y+ S W T+ + +F + P +
Sbjct 151 FLLEWSVSLGDAQVSWLSSKDIEFEVAYKRLQDS-WEDAYSLHTSKFQVNFEPKLFLPNS 209
Query 294 EYVFRIRCMKEDG---KGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
Y R+R G G S WS E ++ +P + G +++
Sbjct 210 IYAARVRTRLSPGSSLSGRPSRWSPEVH---WDSQPGD--KAQPQNLQCFFDGIQSLHCS 264
Query 351 WK---------------TLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR 395
W+ P K + + YT L V +
Sbjct 265 WEVWTQTTGSVSFGLFYRPSPVAPEEKCS----PVVKEPPGASVYTRYHCSLPVPEPSAH 320
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK---- 451
T++V++L + + Q P ++L + + W T + +
Sbjct 321 SQYTVSVKHL----EQGKFIMSYNHIQMEPPTLNLT--KNRDSYSLHWETQKMAYSFIEH 374
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY--LITVTPVYA-DGPGS-- 506
+ +++ SD D + E+ + L Y + V P+ DG S
Sbjct 375 TFQVQYKKKSDSWE---DSKTENLDRAHSMDLSQLEPDTSYCARVRVKPISNYDGIWSKW 431
Query 507 PESIKAYLKQAPP 519
E P
Sbjct 432 SEEYTWKTDWVMP 444
Score = 37.5 bits (85), Expect = 0.61, Method: Composition-based stats.
Identities = 73/445 (16%), Positives = 135/445 (30%), Gaps = 47/445 (11%)
Query 364 LDYEVTLTRWKSHLQN-YTVNATKLTVN------LTNDRYLATLTVRNLVGKSDAAVLT- 415
+++EV R + ++ Y+++ +K VN L N Y A + R G S + +
Sbjct 172 IEFEVAYKRLQDSWEDAYSLHTSKFQVNFEPKLFLPNSIYAARVRTRLSPGSSLSGRPSR 231
Query 416 ---------IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK-KYILEWCVLSDKAP 465
P Q + + W WT SV ++ +
Sbjct 232 WSPEVHWDSQPGDKAQPQNLQCFFDGIQSLHCSWEVWTQTTGSVSFGLFYRPSPVAPEEK 291
Query 466 CITDWQQEDGTVHRTYLRGNL---AESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
C ++ G T +L S TV+ + + S +
Sbjct 292 CSPVVKEPPGASVYTRYHCSLPVPEPSAHSQYTVSVKHLEQGKFIMSYNHIQME-----P 346
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN-YTIFYRTIIGNETAVNVD--SSHTEYTL 579
PT+ K ++ L W+ + FI + + + Y+ + + L
Sbjct 347 PTLNLTK-NRDSYSLHWETQKMAY--SFIEHTFQVQYKKKSDSWEDSKTENLDRAHSMDL 403
Query 580 SSLTSDTLY--MVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGV 637
S L DT Y VR+ ++ G T K +V + + +LT LL +
Sbjct 404 SQLEPDTSYCARVRVKPISNYDGIWSKWSEEYTWKTDWVMPTLWIVLILVFLILTLLLIL 463
Query 638 LFCFNKRDLIKKHIWPNVPDPSKSHIAQ------WSPHTP----PRHNFNSKDQMYSDGN 687
F + +P+PSKS + Q W P + ++ Q
Sbjct 464 RFGCVSVYRTYRKWKEKIPNPSKSLLFQDGGKGLWPPGSMAAFATKNPALQGPQSRLLAE 523
Query 688 FTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDEN 747
S +E N+ P + ++ +T + S + N
Sbjct 524 QQGESYAHLEDNNVSPLTIEDPNIIRVPPSGPDT---TPAASSESTEQLPNVQVEGPTPN 580
Query 748 ESSQNTSSTVQYSTVVHSGYRHQVP 772
+ S + H +P
Sbjct 581 RPRKQLPSFDFNGPYLGPPQSHSLP 605
>sp|A2RUH7|MBPHL_HUMAN Myosin-binding protein H-like OS=Homo sapiens
OX=9606 GN=MYBPHL PE=1 SV=2
Length=354
Score = 59.5 bits (142), Expect = 6e-08, Method: Composition-based stats.
Identities = 29/129 (22%), Positives = 50/129 (39%), Gaps = 17/129 (13%)
Query 194 IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK-SV 252
++ V+ LG + + D + +P PP ++ +++ S+ L WT P +
Sbjct 123 YQLRVQ----LGGLEATA-TIDILVIERPGPPQSIKLVDVWGFSA--TLEWTPPQDTGNT 175
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+L Y +Q + W + R+S V DL Y FR+ + G
Sbjct 176 ALLGYTVQKADTKSGLWFTVLEHY---HRTSCIVSDLIIGNSYAFRVFAENQCGL----- 227
Query 313 WSEEASGIT 321
SE A T
Sbjct 228 -SETAPITT 235
Score = 46.8 bits (109), Expect = 6e-04, Method: Composition-based stats.
Identities = 29/191 (15%), Positives = 60/191 (31%), Gaps = 16/191 (8%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTD 93
++ + ++ + + K +W + + + ++ N S+ F
Sbjct 61 QTYIRKVGDTVNLLIPFQGK-------PKPQAIWTHDGCALDTRRVSVRNGEQDSILF-- 111
Query 94 IASLNIQLTCNILTFGQLE--QNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRE 151
I + QL + I I+ P P+++ + G EW ++
Sbjct 112 IREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQD 171
Query 152 THLETN---FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVT 208
T T +T++ + TSC V + + V AEN G
Sbjct 172 TG-NTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVS-DLIIGNSYAFRVFAENQCGLSE 229
Query 209 SDHINFDPVYK 219
+ I D +
Sbjct 230 TAPITTDLAHI 240
Score = 38.7 bits (88), Expect = 0.25, Method: Composition-based stats.
Identities = 29/220 (13%), Positives = 59/220 (27%), Gaps = 18/220 (8%)
Query 304 EDGKGYWSDWSEEASGITYEDRPSK-APSFWYKIDPSHTQGYRTVQLVWKTLPPFEA--- 359
G+G S E+ P P + + + ++ P +A
Sbjct 31 SPGQGAGSP--TPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWT 88
Query 360 --NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIP 417
+ V++ + + A + + RY + + A TI
Sbjct 89 HDGCALDTRRVSVRNGEQDSILFIREAQRA----DSGRYQLRVQLG-----GLEATATID 139
Query 418 ACDFQATHPVMDLKAFPK-DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGT 476
+ P +K +EWT P+++ +L + V + +
Sbjct 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY 199
Query 477 VHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
+ + +L Y V G I L
Sbjct 200 HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAH 239
>sp|Q866G3|IL12B_BUBBU Interleukin-12 subunit beta OS=Bubalus
bubalis OX=89462 GN=IL12B PE=2 SV=1
Length=327
Score = 59.1 bits (141), Expect = 6e-08, Method: Composition-based stats.
Identities = 45/246 (18%), Positives = 86/246 (35%), Gaps = 43/246 (17%)
Query 100 QLTCN---------ILTFGQLEQNVYGITIISG-LPPEKPKNLSCIVNEGKK-MRCEWDG 148
Q TC+ +L + E ++ I+ P+ L C + C W
Sbjct 87 QYTCHKGGEALSRSLLLLHKKEDGIWSTDILKDQKEPKAKSFLKCEAKDYSGHFTCWWLT 146
Query 149 GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN--------------- 193
T L+ + A + C A + +VD+
Sbjct 147 AISTDLKFSVKSSRGSADPRGVTCGAASLSAEKVSVDHREYNKYTVECQEGSTCPAAEES 206
Query 194 --IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP---- 247
IEV VEA + L K + +F +KP+PP NL + + S ++++W P
Sbjct 207 LLIEVVVEAVHKL-KYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWS 264
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
+ S L + +Q + K+ ++ + T++ + + R++
Sbjct 265 TPHSYFSLTFCVQVQGKNKRE-KKLFMDQTSAKVTCHKDAN--------VRVQARDRYYS 315
Query 308 GYWSDW 313
+WS+W
Sbjct 316 SFWSEW 321
>sp|O88599|MYBPH_RAT Myosin-binding protein H OS=Rattus norvegicus
OX=10116 GN=Mybph PE=1 SV=1
Length=484
Score = 59.9 bits (143), Expect = 6e-08, Method: Composition-based stats.
Identities = 53/307 (17%), Positives = 102/307 (33%), Gaps = 28/307 (9%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNP----SIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
P+ P L++ + S L ++W P S S + +++ + AS W + P
Sbjct 78 PSAPLQLTLEDVSH--SSLTVSWEPPEDLGSWGSRAMCWSSVR---EGASEWVPVNPRPV 132
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS-KAPSFWYKI 336
T+ TV++L ++ R+ + G G + + + P + P +
Sbjct 133 MVTQQ--TVRNLALGDKFFLRVTAVNSAGAGPPAVLDQPVHIQEITEAPKIRVPRHLRQT 190
Query 337 DPSHTQGYRTVQLVWKTLPPFEA----NGKILDYE-VTLTRWKSHLQNYTVNATKLTVNL 391
+Q+ ++ P +A NG LD + V + + +A +
Sbjct 191 YIRQVGESVNLQIPFQGKPKPQASWTHNGHALDSQRVNVRSGDQDSILFIRSAQR----- 245
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK 451
+D LTVR L G A + I + + L N +EW P+++
Sbjct 246 -SDSGRYELTVR-LEGLEAKAAIDILVIEKPGPPSSIKLLDVWGCNAA-LEWMPPQDTGN 302
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIK 511
+L + V + + T +L Y V G +
Sbjct 303 TELLGYTVQKADKKTGQWFTVLERYHPTTCTVSDLIIGNSYSFRVFSENLCG---LSDLA 359
Query 512 AYLKQAP 518
K+
Sbjct 360 TTTKELA 366
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 54/327 (17%), Positives = 96/327 (29%), Gaps = 27/327 (8%)
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI----LDYEVTL 370
T + PS+ + ++ + W+ + G
Sbjct 62 PATPATTKPEAPSEDVPSAPLQLTLEDVSHSSLTVSWEPPEDLGSWGSRAMCWSSVREGA 121
Query 371 TRWKSHLQNYTVNATKLTVNL-TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPV-- 427
+ W + + NL D++ +T N G AVL P + T
Sbjct 122 SEWVPVNPRPVMVTQQTVRNLALGDKFFLRVTAVNSAGAGPPAVLDQPVHIQEITEAPKI 181
Query 428 --------MDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
++ + L + + + + L + + Q+ R
Sbjct 182 RVPRHLRQTYIRQVGESVNLQIPFQGKPKPQASWTHNGHALDSQRVNVRSGDQDSILFIR 241
Query 480 TYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEW 539
+ R + S Y +TV +G + +I + + P +++ V A LEW
Sbjct 242 SAQRSD---SGRYELTVR---LEGLEAKAAIDILVIEK-PGPPSSIKLLDVWGCNAALEW 294
Query 540 DQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
P D N + YT+ G V T T+S L Y R+ +
Sbjct 295 MP-PQDTGNTELLGYTVQKADKKTGQWFTVLERYHPTTCTVSDLIIGNSYSFRVFSENLC 353
Query 599 GGKDGPEFTFTTPKFAQGEIEAIVVPV 625
G D TT + A AI
Sbjct 354 GLSD---LATTTKELAHIHKAAITAKP 377
Score = 39.8 bits (91), Expect = 0.12, Method: Composition-based stats.
Identities = 45/325 (14%), Positives = 85/325 (26%), Gaps = 53/325 (16%)
Query 125 PPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P P L+ + W+ + W + + V
Sbjct 77 VPSAPLQLTLEDVSHSSLTVSWEPPEDLG---------SWGSRAMCWSSVREGASEWVPV 127
Query 185 DYSTVYFVNIEV-----------WVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS 233
+ V V V A N+ G ++ + P +
Sbjct 128 NPRPVMVTQQTVRNLALGDKFFLRVTAVNSAGAGPPAVLDQPVHIQEITEAPKIR--VPR 185
Query 234 EELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
+ ++ + + L+ Q + K ++W+ S R + D
Sbjct 186 HLRQTYIR------QVGESVNLQIPFQGKPKPQASWTH-NGHALDSQRVNVRSGD----Q 234
Query 294 EYVFRIRCMKEDGKGYWS--------DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
+ + IR + G + + + E PS +D
Sbjct 235 DSILFIRSAQRSDSGRYELTVRLEGLEAKAAIDILVIEKP--GPPSSIKLLDVWGCNAA- 291
Query 346 TVQLVWKTLPPFEANGKILDYEV-----TLTRWKSHLQNYTVNATKLTVNLTNDRYLATL 400
L W P N ++L Y V +W + L+ Y ++ + + Y +
Sbjct 292 ---LEWMP-PQDTGNTELLGYTVQKADKKTGQWFTVLERYHPTTCTVSDLIIGNSYSFRV 347
Query 401 TVRNLVGKSDAAVLTIPACDFQATH 425
NL G SD A T
Sbjct 348 FSENLCGLSDLATTTKELAHIHKAA 372
Score = 38.3 bits (87), Expect = 0.35, Method: Composition-based stats.
Identities = 18/108 (17%), Positives = 32/108 (30%), Gaps = 3/108 (3%)
Query 402 VRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
+ + A + + P+ + L V W P E + + S
Sbjct 57 AAHEAPATPATTKPEAPSEDVPSAPLQLTLEDVSHSSLTVSWEPP-EDLGSWGSRAMCWS 115
Query 462 DKAPCITDWQQEDGTV--HRTYLRGNLAESKCYLITVTPVYADGPGSP 507
++W + NLA + + VT V + G G P
Sbjct 116 SVREGASEWVPVNPRPVMVTQQTVRNLALGDKFFLRVTAVNSAGAGPP 163
Score = 34.8 bits (78), Expect = 4.2, Method: Composition-based stats.
Identities = 27/175 (15%), Positives = 57/175 (33%), Gaps = 12/175 (7%)
Query 34 ESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTD 93
++ + Q+ + + K W N + ++ + + S+ F
Sbjct 189 QTYIRQVGESVNLQIPFQGK-------PKPQASWTHNGHALDSQRVNVRSGDQDSILFIR 241
Query 94 IASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETH 153
A + + + + I I+ P P ++ + G EW ++T
Sbjct 242 SAQRSDSGRYELTVRLEGLEAKAAIDILVIEKPGPPSSIKLLDVWGCNAALEWMPPQDTG 301
Query 154 LETN---FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
T +T++ +R PT+CTV + + V +EN G
Sbjct 302 -NTELLGYTVQKADKKTGQWFTVLERYHPTTCTVS-DLIIGNSYSFRVFSENLCG 354
>sp|Q764M8|INAR1_PIG Interferon alpha/beta receptor 1 OS=Sus scrofa
OX=9823 GN=IFNAR1 PE=2 SV=1
Length=560
Score = 59.5 bits (142), Expect = 9e-08, Method: Composition-based stats.
Identities = 63/399 (16%), Positives = 126/399 (32%), Gaps = 48/399 (12%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP-EDTASTRSS 283
P N+ V ++ L W + S +SV + ++ Y+ W ++P + ST +
Sbjct 30 PENVVVSIIDDN---FILKWKS-SSESVSNVTFSADYQITGMDNWIKLPGCQYVTSTECN 85
Query 284 FTVQDLKPFTEYV---FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
F+ LK + Y RIR + S W E I +++ P + +
Sbjct 86 FSSIKLK--SVYEKTKLRIRAETGNST---SPWYEVEPFIPFQEAQIGPPDVHLEAEDKA 140
Query 341 TQGYRTVQLVWKTLPPFEANG-------KILDYEVTLTRWKSHLQNYTVNA-TKLTVNLT 392
+ PP N Y + + + S L+ T + ++
Sbjct 141 IIINLS--------PPGTKNSVMWAMDSSSFVYSLVIWKNSSSLEERTKTVYARDKIHQL 192
Query 393 NDRYLATLTVRNLVGKSD------AAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP 446
+ L V+ + +S + V I +L+ ++ + ++W
Sbjct 193 SPETTYCLKVKAGL-RSPRKVGVYSPVYCINTTVKHHLPSPENLEINAENRVYVLKWNYT 251
Query 447 RESVKKYILEW---CVLSDKAPCITDWQQED----GTVHRTYLRGNLAESKCYLITVTPV 499
E+V + +W + W+Q N+ + I V
Sbjct 252 YENV-TFQAQWLHAFLKKIPEDHSDKWKQIPNCENVKTTHCVFPQNVFTKGIFFIRVQAS 310
Query 500 YADGPGS-PESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
+ E + + P + K + + + Y + Y
Sbjct 311 NGNSTSLWSEEKRFNTEMQTILFPPVINMKPINDASLRVGIGAPKESEDKSVNQLYPLIY 370
Query 559 RTIIGN---ETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
I +T +V T++T S+L T+Y V+ A
Sbjct 371 EVIFRENTSDTERDVLEKRTDFTFSNLKPLTVYCVKARA 409
Score = 52.6 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 66/417 (16%), Positives = 133/417 (32%), Gaps = 52/417 (12%)
Query 129 PKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWAT----HKFADCKAKRDTPTSCTV 184
P+N+ + + +W E+ F+ + K C+ T + +
Sbjct 30 PENVVVSIID-DNFILKWKSSSESVSNVTFSADYQITGMDNWIKLPGCQYVTSTECNFSS 88
Query 185 DYSTVYFVNIEVWVEAENALGKVTSD---HINFDPVYKVKPNPPHNLSVINSEELSSILK 241
+ ++ + AE G TS F P + + PP ++ + E+ + I+
Sbjct 89 IKLKSVYEKTKLRIRAET--GNSTSPWYEVEPFIPFQEAQIGPP-DVHLEA-EDKAIIIN 144
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIP--PEDTASTRSSFTVQDLKPFTEYVFRI 299
L+ P K+ ++ + W E T + + + L P T Y ++
Sbjct 145 LS--PPGTKNSVMWAMDSSSFVYSLVIWKNSSSLEERTKTVYARDKIHQLSPETTYCLKV 202
Query 300 RC--MKEDGKGYWSDW-----SEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW- 351
+ G +S + + + E+ A + Y + ++T T Q W
Sbjct 203 KAGLRSPRKVGVYSPVYCINTTVKHHLPSPENLEINAENRVYVLKWNYTYENVTFQAQWL 262
Query 352 ----KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVN---LTNDRYLATLTVRN 404
K +P + +WK V T T + + N
Sbjct 263 HAFLKKIPEDHS-----------DKWKQIPNCENVKTTHCVFPQNVFTKGIFFIRVQASN 311
Query 405 LVGKSDAAVLTIPACDFQAT--HPVMDLKAFPKDNMLWVEWTTPRESVKK-----YILEW 457
S + + Q PV+++K D L V P+ES K Y L +
Sbjct 312 GNSTSLWSEEKRFNTEMQTILFPPVINMKPI-NDASLRVGIGAPKESEDKSVNQLYPLIY 370
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
V+ + T +++ + NL Y + + + + S+ +
Sbjct 371 EVIFRENTSDT--ERDVLEKRTDFTFSNLKPLTVYCVKARALIENDRWNRSSVFSDT 425
Score = 46.8 bits (109), Expect = 8e-04, Method: Composition-based stats.
Identities = 33/174 (19%), Positives = 63/174 (36%), Gaps = 15/174 (9%)
Query 167 HKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPP 225
+ +C+ + T C + + V+A N + S+ F+ + PP
Sbjct 278 KQIPNCENVKTTH--CVFPQNVFTKGIFFIRVQASNGNSTSLWSEEKRFNTEMQTILFPP 335
Query 226 HNLSVINSEELSSILKL-TWTNPSIKSV---IILKYNIQYRTKDASTWSQIPPEDTASTR 281
+++ + S + + KSV L Y + +R + T D R
Sbjct 336 V-INMKPINDASLRVGIGAPKESEDKSVNQLYPLIYEVIFRENTSDT-----ERDVLEKR 389
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
+ FT +LKP T Y + R + E+ + S S + + + +P W
Sbjct 390 TDFTFSNLKPLTVYCVKARALIENDRWNRS--SVFSDTVCEKTKPGSTSQAWLI 441
>sp|P26221|GUN4_THEFU Endoglucanase E-4 OS=Thermobifida fusca
OX=2021 GN=celD PE=1 SV=2
Length=880
Score = 59.9 bits (143), Expect = 1e-07, Method: Composition-based stats.
Identities = 24/83 (29%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Query 517 APPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
PPS + + V AVL W D + Y +F R G E V ++ T
Sbjct 674 TPPSAPGSPAVRDVTSTSAVLTWSAS-SDTGGSGVAGYDVFLRAGTGQEQKVG-STTRTS 731
Query 577 YTLSSLTSDTLYMVRMAAYTDEG 599
+TL+ L DT Y+ + A + G
Sbjct 732 FTLTGLEPDTTYIAAVVARDNAG 754
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 32/173 (18%), Positives = 63/173 (36%), Gaps = 20/173 (12%)
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPED 276
P+ P + +V + S+ LTW+ S + Y++ R +
Sbjct 672 DVTPPSAPGSPAV--RDVTSTSAVLTWSASSDTGGSGVAGYDVFLRAGTGQ-----EQKV 724
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR---PSKAPSFW 333
++TR+SFT+ L+P T Y+ + G S S S T + P + +
Sbjct 725 GSTTRTSFTLTGLEPDTTYIAAVVARDNA--GNVSQRST-VSFTTLAENGGGPDASCTVG 781
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATK 386
Y + + ++++ + P +E++ T + NAT
Sbjct 782 YSTNDWDSGFTASIRITYHGTAPLS------SWELSFTFPAGQQVTHGWNATW 828
Score = 40.2 bits (92), Expect = 0.12, Method: Composition-based stats.
Identities = 14/107 (13%), Positives = 27/107 (25%), Gaps = 2/107 (2%)
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTY 481
+ P + W+ ++ + + V Q+ T ++
Sbjct 675 PPSAPGSPAVRDVTSTSAVLTWSASSDTGGSGVAGYDVFLRAGTG--QEQKVGSTTRTSF 732
Query 482 LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTK 528
L Y+ V G S S ++ A GP
Sbjct 733 TLTGLEPDTTYIAAVVARDNAGNVSQRSTVSFTTLAENGGGPDASCT 779
>sp|Q9U3P2|SYG2_CAEEL Synaptogenesis protein syg-2 OS=Caenorhabditis
elegans OX=6239 GN=syg-2 PE=1 SV=1
Length=1270
Score = 59.9 bits (143), Expect = 1e-07, Method: Composition-based stats.
Identities = 25/130 (19%), Positives = 51/130 (39%), Gaps = 13/130 (10%)
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
+V A N+ G +DH++ + P+ P NL++ NS + + W
Sbjct 950 KVKCIARNSFG---TDHLSIPIIPPTHPDEPFNLTMTNSTLN--TISVAWEPRFDGGSD- 1003
Query 255 LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
+ ++YR ++ + T ++ + L Y F+IR + +G+ S W+
Sbjct 1004 QIFEVKYRRQNDDLIHLVNT-----THTNLRLSGLATANTYFFQIRSINA--RGFASSWT 1056
Query 315 EEASGITYED 324
T +
Sbjct 1057 SPVIFATLNE 1066
Score = 42.5 bits (98), Expect = 0.023, Method: Composition-based stats.
Identities = 32/163 (20%), Positives = 53/163 (33%), Gaps = 29/163 (18%)
Query 32 SPESPVVQLH-SNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIP---KEQYTIINRTAS 87
P + V SN +C A+ I W N ++P + ++ + N S
Sbjct 329 YPPASVELFGESNIRYGSSANIQCKSLPSNPASQITWIINGRSVPTPTQREFVVENGIVS 388
Query 88 SVTFT------DIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKP------------ 129
S + + + I + C + I II+ PP+ P
Sbjct 389 SSNVSVHSNELSVEAHQINVECMATNPEGSSAKQHVIKIIA--PPKAPIITGLEDRKFFE 446
Query 130 ---KNLSCIVNEGKKMR-CEWDGGRETHLETNFTLKSEWATHK 168
N++C G + W G E HL K +W+ K
Sbjct 447 GDIVNVTCEAQGGNPLAELSWYRGSEKHL-VKGRKKMKWSQVK 488
Score = 41.0 bits (94), Expect = 0.068, Method: Composition-based stats.
Identities = 36/208 (17%), Positives = 70/208 (34%), Gaps = 21/208 (10%)
Query 49 VLKEKCMDYFHVNANYIVWKTNHFTIPK--EQYTIINRT------ASSVTFTDIASLNIQ 100
V K +C Y V VW+ + I K +Y+I+N S++ +I +
Sbjct 890 VAKARCKVYA-VPTVEFVWEKDEQLIKKNSSKYSIVNTQIDYSTYESTLWIKNIVPDDYT 948
Query 101 LTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTL 160
+ + I II P++P NL+ + + W+ + + F +
Sbjct 949 KKVKCIARNSFGTDHLSIPIIPPTHPDEPFNLTMTNSTLNTISVAWEPRFDGGSDQIFEV 1008
Query 161 KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTS--DHINFDPVY 218
K T + + + + NA G +S + F +
Sbjct 1009 KYRRQNDDLIHLVNTTHTNLRLSGLATA---NTYFFQIRSINARGFASSWTSPVIFATLN 1065
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTN 246
+ N+++I +E+L TW
Sbjct 1066 EDG----VNVAMIRNEKLKLT---TWIP 1086
>sp|Q61190|I10R2_MOUSE Interleukin-10 receptor subunit beta OS=Mus
musculus OX=10090 GN=Il10rb PE=1 SV=1
Length=349
Score = 58.3 bits (139), Expect = 1e-07, Method: Composition-based stats.
Identities = 45/212 (21%), Positives = 81/212 (38%), Gaps = 26/212 (12%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
+PP P+ + K + +W+ +TN T +++ +++ KR T C
Sbjct 21 IPP--PEKVRMNSVNFKNI-LQWE--VPAFPKTNLTFTAQYESYRSFQDHCKRTASTQCD 75
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
+ + Y + V V AE A ++ F PV PP + E L+ L L
Sbjct 76 FSHLSKYG-DYTVRVRAELADEHSEWVNVTFCPVEDTIIGPPE----MQIESLAESLHLR 130
Query 244 WTNPSIKSVIIL----------KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
++ P I++ Y +QY + Q+ S S +++L+P+T
Sbjct 131 FSAPQIENEPETWTLKNIYDSWAYRVQYWKNGTNEKFQV-----VSPYDSEVLRNLEPWT 185
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
Y +++ D +WSE T D
Sbjct 186 TYCIQVQGFLLDQNRT-GEWSEPICERTGNDE 216
Score = 49.1 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 51/334 (15%), Positives = 98/334 (29%), Gaps = 47/334 (14%)
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
P ++ + ++W P L + + D + +
Sbjct 18 LGMIPPPEKVRMNSVNFKNILQWEVPAFPKTN--LTFTAQYESYRSFQDHCKRTASTQ-- 73
Query 481 YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD 540
+L++ Y + V AD ++ + P ++ + + L +
Sbjct 74 CDFSHLSKYGDYTVRVRAELADEHSEWVNVTFCPVEDTIIGPPEMQIESL-AESLHLRFS 132
Query 541 QLPVDVQNGFIR--------NYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
++ + Y + Y NE V S + L +L T Y +++
Sbjct 133 APQIENEPETWTLKNIYDSWAYRVQYWKNGTNE-KFQVVSPYDSEVLRNLEPWTTYCIQV 191
Query 593 AAY----TDEGGKDGPEFTFT-----TPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNK 643
+ G P T TP + I + V V FLL + + + K
Sbjct 192 QGFLLDQNRTGEWSEPICERTGNDEITPSWIVAIILIVSVLVVFLFLLGCFVVLWLIYKK 251
Query 644 RD-------LIKKHIWPNVPDPSKSHIAQWS-PHTPPRHNFNSKD----------QMYSD 685
+ +H+ + P S +S P F+ Q D
Sbjct 252 TKHTFRSGTSLPQHLKEFLGHPHHSTFLLFSFPPPEEAEVFDKLSIISEESEGSKQSPED 311
Query 686 G----NFTDVSVVEIEANDKKPFP--EDLKSLDL 713
+D E+E+ D+ P P +D K L
Sbjct 312 NCASEPPSDPGPRELESKDEAPSPPHDDPKLLTS 345
>sp|Q61729|IL12B_MARMO Interleukin-12 subunit beta OS=Marmota
monax OX=9995 GN=IL12B PE=2 SV=1
Length=327
Score = 58.3 bits (139), Expect = 1e-07, Method: Composition-based stats.
Identities = 39/232 (17%), Positives = 79/232 (34%), Gaps = 34/232 (15%)
Query 105 ILTFGQLEQNVYGITIISGLPPEKPKNLSCIV-NEGKKMRCEWDGGRETHLETNFTLKSE 163
+L + E ++ I+ PE ++C N + C W T + NF++KS
Sbjct 101 LLLLHKNEDGIWSTDILKKKEPENKNLVTCEAKNYSGRFTCWWLTAIST--DVNFSVKSH 158
Query 164 WATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL-GKVTSDHINFDPV----- 217
+ T ++ V + V + +NA + I
Sbjct 159 RGSSDPQGVTCGEATLSAERVKIEQREYKKYSVQCQEDNACPTAEETLPITVVVDAVHKL 218
Query 218 ------------YKVKPNPPHNLSVINSEELSSILKLTWTNP----SIKSVIILKYNIQY 261
+KP+PP NL + S + +++TW P + S L +++Q
Sbjct 219 KYENYISSFFIRDIIKPDPPKNLKMKPS-KTPQQVEVTWEYPDSWSTPHSYFSLTFSVQV 277
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ K + + + T+ T + + + ++ WS+W
Sbjct 278 QGKKKKRSNTLHVDKTSVTVTC------QKGAK--VSVQARDRYYNSSWSEW 321
>sp|Q28234|IL12B_CEREL Interleukin-12 subunit beta OS=Cervus elaphus
OX=9860 GN=IL12B PE=2 SV=1
Length=327
Score = 57.9 bits (138), Expect = 1e-07, Method: Composition-based stats.
Identities = 44/246 (18%), Positives = 80/246 (33%), Gaps = 43/246 (17%)
Query 100 QLTCN---------ILTFGQLEQNVYGITIISG-LPPEKPKNLSCIVNEGKK-MRCEWDG 148
Q TC+ +L + E ++ I+ P+ L C + C W
Sbjct 87 QYTCHKGGEVLSRSLLLLHKKEDGIWSTDILKDQKEPKAKSFLKCEAKDYSGHFTCWWLT 146
Query 149 GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN--------------- 193
T L+ + + + C A + VD+
Sbjct 147 AISTDLKFSVKSSRGSSDPRGVTCGAASLSTEKVIVDHREYKKYTVECQEGSACPAAEES 206
Query 194 --IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP---- 247
IEV VEA + L K + +F +KP+PP NL + + S ++++W P
Sbjct 207 LPIEVVVEAVHKL-KYENYTSSFFIRDIIKPDPPKNLQLRPL-KNSRQVEVSWEYPDTWS 264
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
+ S L + +Q + K+ + +A R++
Sbjct 265 TPHSYFSLTFCVQVQGKNKREKKLFMDQTSAKVTCHKDAS---------IRVQARDRYYN 315
Query 308 GYWSDW 313
+WS+W
Sbjct 316 SFWSEW 321
>sp|K7NA32|IRA1A_ONCMY Interferon alpha/beta receptor 1a OS=Oncorhynchus
mykiss OX=8022 GN=ifnar1a PE=2 SV=1
Length=405
Score = 58.3 bits (139), Expect = 1e-07, Method: Composition-based stats.
Identities = 66/367 (18%), Positives = 109/367 (30%), Gaps = 34/367 (9%)
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI---LEWCVLSDKAPCITDWQQEDGTV 477
+L + + W + + + +E+ +W +
Sbjct 19 LAELPQPQNLTLLTLNTQYVLTWDWDQTTTGNSVSFTVEYMAKYKMKMKKKNWSRVCERT 78
Query 478 HRT---YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE 534
RT +L Y++ V ADG S K + S GP R +
Sbjct 79 TRTRCDLTGSDLHYLGMYVLRVRA-SADGVNSDWVNKDFCPDIDASLGPPSRVELAPVGN 137
Query 535 AV-LEWDQLPVDVQNGFIRN-----YTIFY--RTIIGNETAVNV-DSSHTEYTLSSLTSD 585
+ + Q+ + Y I Y R+ V DSS+ TL L +
Sbjct 138 LLDVTISDPLTSTQHSMKEHVLFLYYRILYWSRSDDPQGLKPKVLDSSNNLVTLPELEAW 197
Query 586 TLYMVRMAA----YTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCF 641
T Y V + + Y P+ T G+I + + L LL F
Sbjct 198 TWYCVMIQSRYDYYNKTSSYTEPQCMQTEGDTPYGQIFLYFLVSMMVCFLLVLLSSYAFF 257
Query 642 NKRDLIKKHIWPNVPDPSK-------SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVV 694
+K +P++ P+ S P S+ ++ D VV
Sbjct 258 RFYRGLKNTFYPSIQLPAHIQEYLCDSSPGSDMPRLITAD---SEAELCCDKLTICPEVV 314
Query 695 EIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGI----GGSSCMSSSRPSISSSDENESS 750
+E + P L+ +I + SGI GGS+ S D+ S
Sbjct 315 LLEIHVPPPLTAPPSELEQDSGRRIRQDSGDSGIYSTEGGSAQQGRSGGEPIRRDQEVDS 374
Query 751 QNTSSTV 757
T V
Sbjct 375 WQTLEQV 381
>sp|Q2PE76|IL12B_BUBCA Interleukin-12 subunit beta OS=Bubalus
carabanensis OX=346063 GN=IL12B PE=2 SV=1
Length=327
Score = 57.9 bits (138), Expect = 2e-07, Method: Composition-based stats.
Identities = 44/246 (18%), Positives = 86/246 (35%), Gaps = 43/246 (17%)
Query 100 QLTCN---------ILTFGQLEQNVYGITIISG-LPPEKPKNLSCIVNEGKK-MRCEWDG 148
Q TC+ +L + E ++ I+ P+ L C + C W
Sbjct 87 QYTCHKGGEALSRSLLLLHKKEDGIWSTDILKDQKEPKAKSFLKCEAKDYSGHFTCWWLT 146
Query 149 GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN--------------- 193
T L+ + + + C A + +VD+
Sbjct 147 AISTDLKFSVKSSRGSSDPRGVTCGAASLSAEKVSVDHREYNKYTVECQEGSTCPAAEES 206
Query 194 --IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP---- 247
IEV VEA + L K + +F +KP+PP NL + + S ++++W P
Sbjct 207 LLIEVVVEAVHKL-KYENYTSSFFIRDIIKPDPPKNLQLRPL-KNSRQVEVSWEYPDTWS 264
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
+ S L + +Q + K+ ++ + T++ + + R++
Sbjct 265 TPHSYFSLTFCVQVQGKNKRE-KKLFMDQTSAKVTCHKDAN--------VRVQARDRYYS 315
Query 308 GYWSDW 313
+WS+W
Sbjct 316 SFWSEW 321
>sp|Q9XSQ5|IL12B_HORSE Interleukin-12 subunit beta OS=Equus caballus
OX=9796 GN=IL12B PE=2 SV=1
Length=329
Score = 57.9 bits (138), Expect = 2e-07, Method: Composition-based stats.
Identities = 42/228 (18%), Positives = 73/228 (32%), Gaps = 32/228 (14%)
Query 109 GQLEQNVYGITIISGLPPEKPKN-LSCIV-NEGKKMRCEWDGGRETHLETNFTLKSEWAT 166
+ E ++ I+ K K L C N + C W T L+ + +
Sbjct 105 HKKEDGIWSTDILKDQKESKNKTFLKCEAKNYSGRFTCWWLTAISTDLKFSVKSSRGSSD 164
Query 167 HKFADCKAKRDTPTSCTVDYSTVYFVN-----------------IEVWVEAENALGKVTS 209
+ C A + +VD IE+ V+A + L K +
Sbjct 165 PRGVTCGAATLSAERVSVDDREYKKYTVECQEGSACPAAEESLPIEIVVDAVHKL-KYEN 223
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS----IKSVIILKYNIQYRTKD 265
F +KP+PP NL + + S ++++W P S L ++IQ + K+
Sbjct 224 YTSGFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPETWSTPHSYFSLTFSIQVQGKN 282
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
D S + R++ WS+W
Sbjct 283 KKERKDRLFMDETSATVTCHKDG-------QIRVQARDRYYSSSWSEW 323
>sp|Q8R4S8|CRLF2_RAT Cytokine receptor-like factor 2 OS=Rattus
norvegicus OX=10116 GN=Crlf2 PE=1 SV=1
Length=360
Score = 57.9 bits (138), Expect = 2e-07, Method: Composition-based stats.
Identities = 36/194 (19%), Positives = 65/194 (34%), Gaps = 22/194 (11%)
Query 137 NEGKKMRCEWDGGRETH-LETNFTLKSEWATHKFADCKAK---RDTPTSCTVDYSTVYFV 192
++ + + W G H L N +L+ + C C +
Sbjct 41 HDLESVEVTWGPGSAHHGLSANLSLEFRYGNQVPQPCPHYFLLDSVRAGCVLPMGKGLLE 100
Query 193 NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV 252
V E K+ S + P PP N+++ + ++ + PS S
Sbjct 101 V----VLREGGGAKLFSRKKKASAWLR--PRPPWNVTLSWVGDTVAV-----SCPSH-SY 148
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG-KGYWS 311
L+Y +Q+R W T++ + TV L P Y FR+R +D G +
Sbjct 149 PGLEYEVQHRDDFDPEWQ-----STSAPFCNLTVGGLDPGRCYDFRVRATPQDFYYGPEA 203
Query 312 DWSEEASGITYEDR 325
S+ + +
Sbjct 204 RPSKWTGVASLQGV 217
Score = 37.5 bits (85), Expect = 0.53, Method: Composition-based stats.
Identities = 41/241 (17%), Positives = 70/241 (29%), Gaps = 34/241 (14%)
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSS 573
P V VG AV P G Y + +R E + +
Sbjct 119 SAWLRPRPPWNVTLSWVGDTVAV----SCPSHSYPG--LEYEVQHRDDFDPEWQ-STSAP 171
Query 574 HTEYTLSSLTSDTLYMVRMAAY-------------------TDEGGKDGPEFTFTTPKFA 614
T+ L Y R+ A + +G T T
Sbjct 172 FCNLTVGGLDPGRCYDFRVRATPQDFYYGPEARPSKWTGVASLQGVGPTGSCTGPTLPRT 231
Query 615 QGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRH 674
G + C + L +L + +K+ + P VPDP S + H
Sbjct 232 PGTPTPPLALACGLAVALLTLVLLLALLRMRRVKEALLPGVPDPRGSFPGLFEKHHGNFQ 291
Query 675 NFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCM 734
+ + Q V + + + +P K ++ + + + G S +GG + M
Sbjct 292 AWIADSQ----AAVPTVPEQDKDDDVIRP---QTKGVETQEDDDVIAPG-SPCLGGGALM 343
Query 735 S 735
S
Sbjct 344 S 344
>sp|Q05638|CHIX_STROI Exochitinase 1 OS=Streptomyces olivaceoviridis
OX=1921 GN=chi01 PE=1 SV=1
Length=597
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 35/222 (16%), Positives = 61/222 (27%), Gaps = 27/222 (12%)
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
T N +S ++ L + P V+ +
Sbjct 53 TTVNSPVRSGSSALKATPAGSDNARCAQTVTVQPNSQYTL------SGHVQGSYVYLGAS 106
Query 461 SDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL------ 514
++ W Q R +T+ G G+ + L
Sbjct 107 GTGTTDVSTWTQSAPDW-RQLTTTFRTGPSTTRVTLYTHGWYGTGAYHADDISLVGPGGG 165
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH 574
+ PP+ +RT V L W + Y ++ + +S
Sbjct 166 TEQPPAPPTGLRTGSVTATSVALSWSPVTG------ATGYAVY------RDGVKVATASG 213
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
T T++ LT DT Y ++AA G + + T A G
Sbjct 214 TSATVTGLTPDTAYAFQVAAVNGAG--ESAKSATVTATTAPG 253
Score = 52.2 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 21/109 (19%), Positives = 41/109 (38%), Gaps = 22/109 (20%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P PP L ++ + L+W+ + + Y + YR + ++
Sbjct 169 PPAPPTGLR--TGSVTATSVALSWSPVTGATG----YAV-YRD---------GVKVATAS 212
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
+S TV L P T Y F++ + G+ S +++ +T P
Sbjct 213 GTSATVTGLTPDTAYAFQVAAVNGAGE------SAKSATVTATTAPGTG 255
Score = 50.2 bits (118), Expect = 8e-05, Method: Composition-based stats.
Identities = 28/218 (13%), Positives = 57/218 (26%), Gaps = 32/218 (15%)
Query 318 SGITYEDRPSKAPSFWYKIDPSHTQGYR---TVQLVWKTLPPFEANGKILDYEVTLTRWK 374
+ T + P ++ S K P+ + R TV + + + +G + V L
Sbjct 50 TAGTTVNSPVRSGSSALKATPAGSDNARCAQTVTV--QPNSQYTLSGHVQGSYVYLGASG 107
Query 375 SHLQNYTVNAT------KLTVNLTNDRYLATLTVRNLV--GKS-----DAAVLTIPACDF 421
+ + + +LT +T+ G D +++
Sbjct 108 TGTTDVSTWTQSAPDWRQLTTTFRTGPSTTRVTLYTHGWYGTGAYHADDISLVGPGGGTE 167
Query 422 QATHPVMDL-KAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT 480
Q P L + + W+ + + V D + +
Sbjct 168 QPPAPPTGLRTGSVTATSVALSWSPVTGAT-----GYAVYRDG-------VKVATASGTS 215
Query 481 YLRGNLAESKCYLITVTPVYADGP-GSPESIKAYLKQA 517
L Y V V G ++ A
Sbjct 216 ATVTGLTPDTAYAFQVAAVNGAGESAKSATVTATTAPG 253
>sp|P16382|IL4RA_MOUSE Interleukin-4 receptor subunit alpha OS=Mus
musculus OX=10090 GN=Il4r PE=1 SV=1
Length=810
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 39/195 (20%), Positives = 67/195 (34%), Gaps = 15/195 (8%)
Query 133 SCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFAD---CKAKRDTPTSCTVDYSTV 189
+C + + CEW + L +F++ C + T C
Sbjct 33 TCFSDYIRTSTCEWFLDSAVDCSSQLCLHYRLMFFEFSENLTCIPRNSASTVCVCHMEMN 92
Query 190 YFVN---IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
V ++ + AE+ +F P VKP P NL++ ++ L LTW N
Sbjct 93 RPVQSDRYQMELWAEHR----QLWQGSFSPSGNVKPLAPDNLTL-HTNVSDEWL-LTWNN 146
Query 247 PSIKSVII---LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMK 303
+ ++ L + +D + R SF + L Y R+R
Sbjct 147 LYPSNNLLYKDLISMVNISREDNPAEFIVYNVTYKEPRLSFPINILMSGVYYTARVRVRS 206
Query 304 EDGKGYWSDWSEEAS 318
+ G WS+WS +
Sbjct 207 QILTGTWSEWSPSIT 221
Score = 36.0 bits (81), Expect = 1.9, Method: Composition-based stats.
Identities = 27/150 (18%), Positives = 50/150 (33%), Gaps = 7/150 (5%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQ---NGFIRNYTIFYRTIIGNETAVNVDSSHT 575
P + +E +L W+ L I I NV
Sbjct 124 PLAPDNLTLHTNVSDEWLLTWNNLYPSNNLLYKDLISMVNISREDNPAEFIVYNVTYKEP 183
Query 576 --EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIV-VPVCLAFLLT 632
+ ++ L S Y R+ + E++ + + ++ I +P+ +
Sbjct 184 RLSFPINILMSGVYYTARVRVRSQILTGTWSEWSPSITWYNHFQLPLIQRLPLGVTISCL 243
Query 633 TL-LGVLFCFNKRDLIKKHIWPNVPDPSKS 661
+ L LFC+ IKK W +P P++S
Sbjct 244 CIPLFCLFCYFSITKIKKIWWDQIPTPARS 273
>sp|Q16473|TENXA_HUMAN Putative tenascin-XA OS=Homo sapiens OX=9606
GN=TNXA PE=5 SV=2
Length=311
Score = 57.6 bits (137), Expect = 2e-07, Method: Composition-based stats.
Identities = 42/260 (16%), Positives = 83/260 (32%), Gaps = 36/260 (14%)
Query 346 TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA--TKLTVNLTNDRYLATLTVR 403
+++L W A G + V Q V+ +K+ ++ +
Sbjct 59 SMRLSW-----SVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLY 113
Query 404 -----------NLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
+ G + A + + + + + + L + W P +
Sbjct 114 GLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSS-LRLNWEAPPGAFDS 172
Query 453 YILEWCVLSDK------APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS 506
++L + V S P + GT H LR L Y +T+ + GP
Sbjct 173 FLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRD-LRSGTLYSLTLYGLR--GPHK 229
Query 507 PESIKAYLKQAPP--SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN 564
+SI+ + P ++ ++ + A + W P ++ + Y+ G
Sbjct 230 ADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPP-----SRADSFKVSYQLADGG 284
Query 565 E-TAVNVDSSHTEYTLSSLT 583
E +V VD L LT
Sbjct 285 EPQSVQVDGRARTQKLQFLT 304
Score = 44.1 bits (102), Expect = 0.004, Method: Composition-based stats.
Identities = 37/272 (14%), Positives = 83/272 (31%), Gaps = 20/272 (7%)
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
+ ++ ++L+W S+ + +QY + + + +S +
Sbjct 49 VLTVTDTTPDSMRLSW---SVAQGPFDSFVVQYEDTNGQPQALL----VDGDQSKILISG 101
Query 289 LKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ 348
L+P T Y F + + +GK +E +G+ + S+ +++
Sbjct 102 LEPSTPYRFLLYGL-HEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLR 160
Query 349 LVWKTLPPFEANGKILDYEVTLTRWKSHLQ-------NYTVNATKLTVNLTNDRYLATLT 401
L W+ P + + + + + H + + L +LT
Sbjct 161 LNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLT 220
Query 402 VRNLVGKSDAAVLTIPACDFQAT-HPVMDLK-AFPKDNMLWVEWTTPRESVKKYILEWCV 459
+ L G A + A DL+ + ++ V W P + + + +
Sbjct 221 LYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQL 280
Query 460 LSDKAPCITDWQQEDGTVHRTYLRGNLAESKC 491
P DG L+ C
Sbjct 281 ADGGEPQSVQ---VDGRARTQKLQFLTVPHSC 309
Score = 37.5 bits (85), Expect = 0.41, Method: Composition-based stats.
Identities = 13/66 (20%), Positives = 22/66 (33%), Gaps = 5/66 (8%)
Query 525 VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTS 584
+ + L W V G ++ + Y G A+ VD ++ +S L
Sbjct 50 LTVTDTTPDSMRLSW-----SVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEP 104
Query 585 DTLYMV 590
T Y
Sbjct 105 STPYRF 110
>sp|P46282|IL12B_BOVIN Interleukin-12 subunit beta OS=Bos taurus
OX=9913 GN=IL12B PE=2 SV=1
Length=327
Score = 57.6 bits (137), Expect = 2e-07, Method: Composition-based stats.
Identities = 44/251 (18%), Positives = 89/251 (35%), Gaps = 53/251 (21%)
Query 100 QLTCN---------ILTFGQLEQNVYGITIISG-LPPEKPKNLSCIVNEGKK-MRCEWDG 148
Q TC+ +L + E ++ I+ P+ L C + C W
Sbjct 87 QYTCHKGGEALSRSLLLLHKKEDGIWSTDILKDQKEPKAKSFLKCEAKDYSGHFTCWWLT 146
Query 149 GRETHLETNFTLKSEWAT----------------------HKFADCKAKRDTPTSCTVDY 186
T L F++KS + ++ + ++C
Sbjct 147 AISTDL--KFSVKSSRGSSDPRGVTCGAALLSAEKVSLEHREYNKYTVECQEGSACPAAE 204
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
++ IEV VEA + L K + +F +KP+PP NL + + S ++++W
Sbjct 205 ESLL---IEVVVEAVHKL-KYENYTSSFFIRDIIKPDPPKNLQLRPL-KNSRQVEVSWEY 259
Query 247 P----SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
P + S L + +Q + K+ ++ + T++ + + R++
Sbjct 260 PDTWSTPHSYFSLTFCVQVQGKNKRE-KKLFMDQTSAKVTCHKDAN--------VRVQAR 310
Query 303 KEDGKGYWSDW 313
+WS+W
Sbjct 311 DRYYSSFWSEW 321
>sp|O61460|VAB1_CAEEL Ephrin receptor 1 OS=Caenorhabditis elegans
OX=6239 GN=vab-1 PE=1 SV=1
Length=1122
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 36/240 (15%), Positives = 68/240 (28%), Gaps = 26/240 (11%)
Query 92 TDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWD-GGR 150
++ S +C L ++ I++ PP +P L R W+
Sbjct 309 SNSISSEAASSCRCLNGYFRAEDEL-ISMPCTQPPSRPIKLVANAITATSTRLSWNEPSS 367
Query 151 ETHLETN-FTLKSEWATH--KFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG-- 205
+ +K + T + V A+N +
Sbjct 368 LGGRPEIWYEVKCSGRGECGTVVMTPGDKKLSTRSVQINGLRPSSDYTFLVFAKNKVSAQ 427
Query 206 ----KVTSDHINFDPVYKVKPNPP-HNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQ 260
+ I+ + + PP +L V S + + W S+ + + ++
Sbjct 428 FPEFSEKNAVIDIRTRSEEEDVPPVSHLRVDA--SQSDGITIAW---SVSDSDVSDFEVE 482
Query 261 YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
R T ++F L P T Y FR+R + WS+ S
Sbjct 483 VRPAIVKK-RTFETRHVNMTYTTFI--GLNPETVYQFRVRIRDDL------RWSQPISYQ 533
Score = 57.2 bits (136), Expect = 6e-07, Method: Composition-based stats.
Identities = 36/266 (14%), Positives = 88/266 (33%), Gaps = 25/266 (9%)
Query 158 FTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL----GKVTSDHIN 213
++ ++ + C P ++ S + + EA ++ G ++
Sbjct 277 YSQIADSNGARCESCPTNTYKPKGQSLCKSC---PSNSISSEAASSCRCLNGYFRAEDEL 333
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS-IKSVIILKYNIQYRTKDASTWSQI 272
P+ P L S+ +L+W PS + + Y ++ + +
Sbjct 334 ISMPCTQPPSRPIKLVANAITATST--RLSWNEPSSLGGRPEIWYEVKCSGRGECGTVVM 391
Query 273 PPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGY--WSDWSEEASGITYEDRPSKAP 330
P D + S + L+P ++Y F + + + +S+ + T + P
Sbjct 392 TPGDKKLSTRSVQINGLRPSSDYTFLVFAKNKVSAQFPEFSEKNAVIDIRTRSEEEDVPP 451
Query 331 SFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW-----KSHLQNYTVNAT 385
++D S + G + + W ++ + D+EV + ++ + T
Sbjct 452 VSHLRVDASQSDG---ITIAW-----SVSDSDVSDFEVEVRPAIVKKRTFETRHVNMTYT 503
Query 386 KLTVNLTNDRYLATLTVRNLVGKSDA 411
Y + +R+ + S
Sbjct 504 TFIGLNPETVYQFRVRIRDDLRWSQP 529
Score = 51.4 bits (121), Expect = 5e-05, Method: Composition-based stats.
Identities = 24/189 (13%), Positives = 52/189 (28%), Gaps = 21/189 (11%)
Query 419 CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTV- 477
C + P+ + + W P + + + V G
Sbjct 338 CTQPPSRPIKLVANAITATSTRLSWNEPSSLGGRPEIWYEVKCSGRGECGTVVMTPGDKK 397
Query 478 --HRTYLRGNLAESKCYLITVTPVYADGPGSPE--------SIKAYLKQAPPSKGPTVRT 527
R+ L S Y V PE I+ ++ +R
Sbjct 398 LSTRSVQINGLRPSSDYTFLVFAKNKVSAQFPEFSEKNAVIDIRTRSEEEDVPPVSHLRV 457
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV---NVDSSHTEYTLSSLTS 584
+ + W + + ++ + R I + +V+ ++T + L
Sbjct 458 DASQSDGITIAWSVS-----DSDVSDFEVEVRPAIVKKRTFETRHVNMTYTTFI--GLNP 510
Query 585 DTLYMVRMA 593
+T+Y R+
Sbjct 511 ETVYQFRVR 519
Score = 39.1 bits (89), Expect = 0.23, Method: Composition-based stats.
Identities = 16/94 (17%), Positives = 27/94 (29%), Gaps = 6/94 (6%)
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS----S 573
PPS+ + + L W++ I Y + T V S
Sbjct 341 PPSRPIKLVANAITATSTRLSWNEPSSLGGRPEIW-YEVKCSGRGECGTVVMTPGDKKLS 399
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFT 607
++ L + Y + A PEF+
Sbjct 400 TRSVQINGLRPSSDYTFLVFAKNKV-SAQFPEFS 432
>sp|A6QLN9|VWA1_BOVIN von Willebrand factor A domain-containing
protein 1 OS=Bos taurus OX=9913 GN=VWA1 PE=2 SV=1
Length=413
Score = 57.9 bits (138), Expect = 2e-07, Method: Composition-based stats.
Identities = 33/208 (16%), Positives = 58/208 (28%), Gaps = 11/208 (5%)
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEW-TTPRESVKKYILEWCVLSDKAPCITDWQ 471
+ A P + + + W + Y+LE + P Q
Sbjct 200 TQALRGSILDAMWPQQLHASEVTSSGFRLAWPSLLTADSGYYVLE--LAPSTDPGAARRQ 257
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
Q G G L Y + + P + ++ P GP +
Sbjct 258 QLPGNATGWAWTG-LDSDTDYDVALVPESNVRLLRSQHLRVRT--LPEETGPELIVVSHT 314
Query 532 -KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE-TAVNVDSSHTEYTLSSLTSDTLYM 589
+ W P + + Y + + G +V V + TL L T Y+
Sbjct 315 RPRSLRVSW--APALGPDAAL-GYHVQVGPLRGGAAQSVEVPAGENSTTLQGLAPGTAYL 371
Query 590 VRMAAYTDEGGKDGPEFTFTTPKFAQGE 617
V + A G + TP+ +
Sbjct 372 VTVTAAFRSGRERALSAKACTPEGERSR 399
Score = 55.2 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 36/206 (17%), Positives = 72/206 (35%), Gaps = 21/206 (10%)
Query 129 PKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYST 188
P+ L R W T + L+ +T A + + +
Sbjct 213 PQQLHASEVTSSGFRLAW-PSLLTADSGYYVLELAPSTDPGAARRQQLPGNATGWAWTGL 271
Query 189 VYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNP----PHNLSVINSEELSSILKLTW 244
+ +V + E+ + + S H+ +V+ P P + V ++ L+++W
Sbjct 272 DSDTDYDVALVPESNVRLLRSQHL------RVRTLPEETGPELIVVSHT--RPRSLRVSW 323
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
P++ L Y++Q + + +S T+Q L P T Y+ +
Sbjct 324 A-PALGPDAALGYHVQVGPLRGGAAQSVE---VPAGENSTTLQGLAPGTAYLVTVTAAFR 379
Query 305 DGKGYWSDWSEEASGITYEDRPSKAP 330
G+ + + A T E S+AP
Sbjct 380 SGR----ERALSAKACTPEGERSRAP 401
Score = 43.7 bits (101), Expect = 0.007, Method: Composition-based stats.
Identities = 38/201 (19%), Positives = 68/201 (34%), Gaps = 13/201 (6%)
Query 332 FWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNAT--KLTV 389
W + + +L W +L ++ +L+ + + Q NAT T
Sbjct 211 MWPQQLHASEVTSSGFRLAWPSLLTADSGYYVLELAPSTDPGAARRQQLPGNATGWAWTG 270
Query 390 NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTT--PR 447
++ Y L + V + L + + T P + + + + L V W
Sbjct 271 LDSDTDYDVALVPESNVRLLRSQHLRVRTLP-EETGPELIVVSHTRPRSLRVSWAPALGP 329
Query 448 ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSP 507
++ Y ++ L A + + T L+G LA YL+TVT + G
Sbjct 330 DAALGYHVQVGPLRGGAAQSV---EVPAGENSTTLQG-LAPGTAYLVTVTAAFRSGRERA 385
Query 508 ESIKAYLKQA----PPSKGPT 524
S KA + P P
Sbjct 386 LSAKACTPEGERSRAPRPQPQ 406
>sp|P59383|LRRN4_MOUSE Leucine-rich repeat neuronal protein 4
OS=Mus musculus OX=10090 GN=Lrrn4 PE=1 SV=2
Length=733
Score = 58.3 bits (139), Expect = 3e-07, Method: Composition-based stats.
Identities = 26/116 (22%), Positives = 40/116 (34%), Gaps = 7/116 (6%)
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
P+PP V SE + + + W P + ++L Y I Y + S + D
Sbjct 573 EDTTPDPPTLQGV--SEVTDTSVLVHWCAP---NSVVLWYQIHYVAEGRSGNQSV--VDI 625
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
+T + L P T Y + G S T+ +PS FW
Sbjct 626 YATARQHPLYKLTPGTTYHVCVLAANRAGLSQSQTSGWRRSCATFTTKPSSVVIFW 681
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 26/149 (17%), Positives = 49/149 (33%), Gaps = 16/149 (11%)
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY--RTIIGNETAVNVDS 572
+ P +V ++ W N + Y I Y GN++ V++ +
Sbjct 573 EDTTPDPPTLQGVSEVTDTSVLVHW-----CAPNSVVLWYQIHYVAEGRSGNQSVVDIYA 627
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF-------TFTTPKFAQGEIEAIVVPV 625
+ ++ L LT T Y V + A G TFTT + + +
Sbjct 628 TARQHPLYKLTPGTTYHVCVLAANRAGLSQSQTSGWRRSCATFTTKPSSV--VIFWGLCT 685
Query 626 CLAFLLTTLLGVLFCFNKRDLIKKHIWPN 654
LL + L + C ++ + +
Sbjct 686 ASGLLLVSTLVLSVCLWRQRWKPHRQFYD 714
Score = 43.7 bits (101), Expect = 0.008, Method: Composition-based stats.
Identities = 17/124 (14%), Positives = 30/124 (24%), Gaps = 12/124 (10%)
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
+ D P + + D + V W P V Y + + +
Sbjct 570 LSGEDTTPDPPTLQGVSEVTDTSVLVHWCAPNSVVLWYQIHYVAEGRSGNQSV---VDIY 626
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEA 535
R + L Y + V G S + + T +
Sbjct 627 ATARQHPLYKLTPGTTYHVCVLAANRAGL-SQSQTSGWRRSCA--------TFTTKPSSV 677
Query 536 VLEW 539
V+ W
Sbjct 678 VIFW 681
>sp|Q08334|I10R2_HUMAN Interleukin-10 receptor subunit beta OS=Homo
sapiens OX=9606 GN=IL10RB PE=1 SV=2
Length=325
Score = 57.2 bits (136), Expect = 3e-07, Method: Composition-based stats.
Identities = 48/216 (22%), Positives = 82/216 (38%), Gaps = 28/216 (13%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCT 183
+PP P+N+ K + +W+ + N T +++ +++ K T T C
Sbjct 21 VPP--PENVRMNSVNFKNI-LQWESPA--FAKGNLTFTAQYLSYRIFQDKCMNTTLTECD 75
Query 184 VDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
S + + + V AE A +I F PV PP + E L+ L +
Sbjct 76 FS-SLSKYGDHTLRVRAEFADEHSDWVNITFCPVDDTIIGPPG----MQVEVLADSLHMR 130
Query 244 WTNPSIKSVIIL----------KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT 293
+ P I++ YN+QY QI P+ +++L+P+T
Sbjct 131 FLAPKIENEYETWTMKNVYNSWTYNVQYWKNGTDEKFQITPQYDFE-----VLRNLEPWT 185
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITY--EDRPS 327
Y ++R D + +WSE T E PS
Sbjct 186 TYCVQVRGFLPD-RNKAGEWSEPVCEQTTHDETVPS 220
Score = 42.5 bits (98), Expect = 0.012, Method: Composition-based stats.
Identities = 24/153 (16%), Positives = 48/153 (31%), Gaps = 18/153 (12%)
Query 554 YTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY----TDEGGKDGPEFTFT 609
Y + Y +E + + L +L T Y V++ + G P T
Sbjct 154 YNVQYWKNGTDE-KFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQT 212
Query 610 TPKFAQGEIEAIVVPVC----LAFLLTTLLGVLFCFNK--------RDLIKKHIWPNVPD 657
T V+ + + L +L+C K R+ + +H+ +
Sbjct 213 THDETVPSWMVAVILMASVFMVCLALLGCFALLWCVYKKTKYAFSPRNSLPQHLKEFLGH 272
Query 658 PSKSHIAQWS-PHTPPRHNFNSKDQMYSDGNFT 689
P + + +S P + F+ + D
Sbjct 273 PHHNTLLFFSFPLSDENDVFDKLSVIAEDSESG 305
>sp|Q25197|HTK7_HYDVU Putative insulin-like peptide receptor OS=Hydra
vulgaris OX=6087 GN=HTK7 PE=2 SV=1
Length=1477
Score = 58.3 bits (139), Expect = 3e-07, Method: Composition-based stats.
Identities = 70/484 (14%), Positives = 135/484 (28%), Gaps = 89/484 (18%)
Query 239 ILKLTWT-NPSIKSVIILKYNIQYRTKDA---------------STWSQIPPEDTASTR- 281
+K+TW + IL Y I ++ + W+ I +
Sbjct 543 CVKVTWNFTMTSAYNNILFYAIYFKELQSNQEAVVQLDNECQNNDDWNVITVDIPKIESL 602
Query 282 ------SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
S + L P+T Y F I+ + G+ S +D PS+
Sbjct 603 EQSLFLQSKIISKLTPYTRYAFYIKEIVSKGE---ERSSHIHYINISQDLPSEPLGVE-- 657
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDR 395
+ + L W+ P + NG I +++ + + + + D+
Sbjct 658 ---ASFLSENKILLKWRA--PSKPNGIITAFKIYYNKPDYSFWEEQKVLDWCSRDASRDK 712
Query 396 YLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVK--KY 453
+ + ++ I + +KA + + VE+ T V K
Sbjct 713 NAKDVAGYPVNKENYNQYCNISCVCDEEKENSKAIKADREAHNFNVEFQTELMRVLFTKN 772
Query 454 ILEWCVLSDKAPCITDWQQEDG-------TVHRT-----------------------YLR 483
+ + P I + T T Y+
Sbjct 773 KFSYRNKNKSPPKIDFSKNISLILSNKILTSTSTTVTQAKIEIIEEPKVTVNGNIFSYVI 832
Query 484 GNLAESKCYLITVTPVYADGPGSPES--------IKAYLKQAPPSKGPTVRTK----KVG 531
L + Y + V G P S ++A + +K +V
Sbjct 833 SGLDYFEDYELKVCGCTVVGCRRPSSTINLDCGIVQARTG--VNLTADNLDSKMVRVQVQ 890
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYR-TIIGNETAVNVDSSHTEYTLSSLTSDTLYMV 590
+ + W + N I Y I R + + + Y + + Y+
Sbjct 891 LDSYNISW--IAPHKPNAVILKYEISIRYALDKDALVICRPGYLPTYIIRK-SRFGNYVA 947
Query 591 RMAAYTDEGGKDGPEF------TFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
++ A + G E + K I I+ V + + +L+ F R
Sbjct 948 KIRAISPAGNGSWTEEIHFKVAELSVTKNNNQLIIGIISAVSAVIVALLVFILLYMFLHR 1007
Query 645 DLIK 648
L K
Sbjct 1008 KLEK 1011
Score = 52.6 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 34/248 (14%), Positives = 77/248 (31%), Gaps = 38/248 (15%)
Query 60 VNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQL-EQNVYGI 118
V+ I ++ N P + +R + + + + + +++ L + + +
Sbjct 462 VSDGGIFFQYNPRLCPLHIRNLQDR----IHYKNGSKVTGEVSLQNNGHKVLCDTQMLVM 517
Query 119 TIISGLPPEKPKNLSCIVNEGKKMRC---EWDGGRETHLETNFTLKSEWATHKFADCKAK 175
+ +PP+ E +C W+ T N + + ++ +A
Sbjct 518 HVEEFIPPDLNMETDMTAIECNSFKCVKVTWN-FTMTSAYNNILFYAIYFKELQSNQEAV 576
Query 176 RDTPTSCTVD---------------------------YSTVYFVNIEVWVEAENALGKVT 208
C + + +++ + G+
Sbjct 577 VQLDNECQNNDDWNVITVDIPKIESLEQSLFLQSKIISKLTPYTRYAFYIKEIVSKGEER 636
Query 209 SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST 268
S HI++ + + P+ P + E + L W PS + II + I Y D S
Sbjct 637 SSHIHYINISQDLPSEPLGVEASFLSENK--ILLKWRAPSKPNGIITAFKIYYNKPDYSF 694
Query 269 WSQIPPED 276
W + D
Sbjct 695 WEEQKVLD 702
Score = 50.2 bits (118), Expect = 1e-04, Method: Composition-based stats.
Identities = 34/169 (20%), Positives = 56/169 (33%), Gaps = 16/169 (9%)
Query 152 THLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG-KVTSD 210
T T T + + YF + E+ V +G + S
Sbjct 802 TSTSTTVTQAKIEIIEEPKVTVNGNIFSYVISG---LDYFEDYELKVCGCTVVGCRRPSS 858
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKL-------TWTNPSIKSVIILKYNIQYRT 263
IN D V+ NL+ N + +++ +W P + +ILKY I R
Sbjct 859 TINLD-CGIVQARTGVNLTADNLDSKMVRVQVQLDSYNISWIAPHKPNAVILKYEISIRY 917
Query 264 KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
I T + ++ F YV +IR + G G W++
Sbjct 918 ALDKDALVICRPGYLPT---YIIRK-SRFGNYVAKIRAISPAGNGSWTE 962
>sp|Q7Z7G0|TARSH_HUMAN Target of Nesh-SH3 OS=Homo sapiens OX=9606
GN=ABI3BP PE=1 SV=2
Length=1068
Score = 58.3 bits (139), Expect = 3e-07, Method: Composition-based stats.
Identities = 35/161 (22%), Positives = 61/161 (38%), Gaps = 19/161 (12%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
NPP NL+V+ E S + L W P + + +Y + R + + + T ++
Sbjct 832 NPPTNLTVVTVEGCPSFVILDWEKPL--NDTVTEYEVISRENGSFSGKNKSIQMT--NQT 887
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT- 341
TV++LKP T Y F+++ G+G S + T P + D T
Sbjct 888 FSTVENLKPNTSYEFQVKPKNPLGEG---PVSNTVAFSTESADPRVSEPVSAGRDAIWTE 944
Query 342 -----------QGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
+G + V+ W L Y++ L+
Sbjct 945 RPFNSDSYSECKGKQYVKRTWYKKFVGVQLCNSLRYKIYLS 985
Score = 51.0 bits (120), Expect = 6e-05, Method: Composition-based stats.
Identities = 18/122 (15%), Positives = 43/122 (35%), Gaps = 7/122 (6%)
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD---NMLWVEWTTPRESVKKYILEW 457
++ + V + T +P +L + + + ++W P + E+
Sbjct 808 SITDSVKRFPKEEATEGNATSPPQNPPTNLTVVTVEGCPSFVILDWEKPLNDT---VTEY 864
Query 458 CVLSDKAPCITDWQQEDGTVHRTY-LRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQ 516
V+S + + + ++T+ NL + Y V P G G + A+ +
Sbjct 865 EVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTE 924
Query 517 AP 518
+
Sbjct 925 SA 926
Score = 41.8 bits (96), Expect = 0.040, Method: Composition-based stats.
Identities = 25/117 (21%), Positives = 38/117 (32%), Gaps = 16/117 (14%)
Query 492 YLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD---------QL 542
YLI V P P K+ + K + + + L W L
Sbjct 92 YLIVVRPA-----PPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLINPHHDWTL 146
Query 543 PVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
P N R YTI YR + + TE + +L +T+Y + + G
Sbjct 147 PSHCPND--RFYTIRYREKDKEKKWIFQICPATETIVENLKPNTVYEFGVKDNVEGG 201
Score = 41.8 bits (96), Expect = 0.041, Method: Composition-based stats.
Identities = 17/106 (16%), Positives = 36/106 (34%), Gaps = 12/106 (11%)
Query 517 APPSKGP-TVRTKKVG--KNEAVLEWDQLPVDVQNGFIRNYTIFYRTII---GNETAVNV 570
+PP P + V + +L+W++ N + Y + R G ++ +
Sbjct 828 SPPQNPPTNLTVVTVEGCPSFVILDWEKP----LNDTVTEYEVISRENGSFSGKNKSIQM 883
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD-GPEFTFTTPKFAQ 615
+ T+ +L +T Y ++ G F+T
Sbjct 884 TNQTFS-TVENLKPNTSYEFQVKPKNPLGEGPVSNTVAFSTESADP 928
Score = 35.6 bits (80), Expect = 2.6, Method: Composition-based stats.
Identities = 31/133 (23%), Positives = 51/133 (38%), Gaps = 31/133 (23%)
Query 205 GKVTSDHINFDPVY--KVKPNPPHN--------------LSVINSEELSSILKLTW---- 244
GK T ++ +P Y V+P PP + L ++ S + L+W
Sbjct 79 GKFTEAIVDAEPKYLIVVRPAPPPSQKKSCSGKTRSRKPLQLVVGTLTPSSVFLSWGFLI 138
Query 245 ---TNPSIKSVII--LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
+ ++ S Y I+YR KD + + +T + V++LKP T Y F +
Sbjct 139 NPHHDWTLPSHCPNDRFYTIRYREKDKE--KKWIFQICPATET--IVENLKPNTVYEFGV 194
Query 300 RCMKEDGKGYWSD 312
G WS
Sbjct 195 --KDNVEGGIWSK 205
>sp|Q61G93|ROL3_CAEBR Protein roller-3 OS=Caenorhabditis briggsae
OX=6238 GN=rol-3 PE=3 SV=3
Length=2439
Score = 57.9 bits (138), Expect = 5e-07, Method: Composition-based stats.
Identities = 62/405 (15%), Positives = 101/405 (25%), Gaps = 74/405 (18%)
Query 159 TLKSEWATHKFAD-CKAKRDTPTSCTV-DYSTVYFVNIEVWVEAEN--ALGKVTSDHINF 214
T + T K D K R V + + +V V N + S +F
Sbjct 1439 TQYEIYFTRKNTDKVKHVRSFSDRIHVENGILDKETDYDVTVTWLNRYSPASGVSSSRSF 1498
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
P+ P + I + L W+ P + I I+Y+ + +P
Sbjct 1499 R-TGFGYPSAPRDPHAI--PVTPDTVYLYWSLPETLNAPIS--EIKYKISQQAAGISVPT 1553
Query 275 EDTASTRS-------------------SFTVQDLKPFTEYVFRIRCMKEDGKGYWS---- 311
S + +L+P EY F + +
Sbjct 1554 SIAVIPLSETVSSNISSDTTACLINPCRVKIANLRPSNEYKFWVTATHISHLDAATILKD 1613
Query 312 --DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKI-LDYEV 368
S EA T D P + P + G ++ L W L P I + Y
Sbjct 1614 DDAVSSEAVARTL-DVPGT-------LRPDNVTGS-SLLLRWNGLEPEHRPTSIAIQYRE 1664
Query 369 TLT---RWKSHLQNYTVNA-----TKLTVNLTNDRYLATLTV-RNLVGKSDAAVLTIPAC 419
+ W+S +T L+ Y D VL
Sbjct 1665 SGGANNEWQSPTNASFEPDVATELVPVTNLLSATTYDYRFVATYTGTYTIDGKVLAFKED 1724
Query 420 DFQ----------ATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSD------- 462
Q ++A V W P I + V +
Sbjct 1725 YLQLIQQARTKAGVPTAPQSVEAKIDTEGWIVTWKEPMSDGGSPITSYAVETRINKTAEW 1784
Query 463 --KAPCITDWQQ--EDGTVHRTYLRGNLAESKCYLITVTPVYADG 503
+ W+ G + +E + I + G
Sbjct 1785 EIAERGLDGWKTWWRPGKSETSSSMSYSSEVSEFRIRAANIEGFG 1829
Score = 51.4 bits (121), Expect = 5e-05, Method: Composition-based stats.
Identities = 24/135 (18%), Positives = 36/135 (27%), Gaps = 25/135 (19%)
Query 484 GNLAESKCYLITVTPVYADGP--GSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
G L + Y +TVT + P G S PS V + L W
Sbjct 1468 GILDKETDYDVTVTWLNRYSPASGVSSSRSFRTGFGYPSAPRDPHAIPVTPDTVYLYWSL 1527
Query 542 LPVDVQNGFI--RNYTIFYRTII------------GNETAVNVDSSHT-------EYTLS 580
+ N I Y I + + N+ S T ++
Sbjct 1528 --PETLNAPISEIKYKISQQAAGISVPTSIAVIPLSETVSSNISSDTTACLINPCRVKIA 1585
Query 581 SLTSDTLYMVRMAAY 595
+L Y + A
Sbjct 1586 NLRPSNEYKFWVTAT 1600
Score = 40.2 bits (92), Expect = 0.10, Method: Composition-based stats.
Identities = 34/212 (16%), Positives = 62/212 (29%), Gaps = 35/212 (17%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWAT------HKFADCKAKRDTPT 180
+ P L G + W+G H T+ ++ + + + D T
Sbjct 1627 DVPGTLRPDNVTGSSLLLRWNGLEPEHRPTSIAIQYRESGGANNEWQSPTNASFEPDVAT 1686
Query 181 SCTVDYSTVYFVNIEVWVEAE-----NALGKV---TSDHINFDPVYKVKPNPPHNL-SVI 231
+ + + A GKV D++ + K P SV
Sbjct 1687 ELVPVTNLLSATTYDYRFVATYTGTYTIDGKVLAFKEDYLQLIQQARTKAGVPTAPQSVE 1746
Query 232 NSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
+ + +TW P S I Y ++ R + W +I ++ + +
Sbjct 1747 AKIDTEGWI-VTWKEPMSDGGSPITSYAVETRINKTAEW-EIAERGLDGWKTWW-----R 1799
Query 291 PFT------------EYVFRIRCMKEDGKGYW 310
P FRIR +G G +
Sbjct 1800 PGKSETSSSMSYSSEVSEFRIRAANIEGFGAY 1831
Score = 38.7 bits (88), Expect = 0.36, Method: Composition-based stats.
Identities = 32/191 (17%), Positives = 59/191 (31%), Gaps = 11/191 (6%)
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNI-QYRTKDASTWSQIPPEDTASTRSSFTVQ 287
+ E + L+ T + P +I K + + + DT T ++
Sbjct 953 EIKFMEGSKTDLQWTLSPPLEAGTVIFKVSFFREKMGGQDAPITTIQSDTNFTIPPEVLK 1012
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK--IDPSHTQGYR 345
+ + I+ + W+ +G+T +P P+ G R
Sbjct 1013 EWSSAQRFDVSIQAIT-----PWATAVLNRTGLTAPVKPPTPPTQLKIFATQQKTVDGPR 1067
Query 346 TVQ-LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRN 404
+ W PP E NG Y V T+ + + K V L +L + N
Sbjct 1068 ALISFFW--GPPLEWNGTPYQYIVNCTKDDGKVITIDSSELKPLVKLFAIDSTNSLIIIN 1125
Query 405 LVGKSDAAVLT 415
+ + T
Sbjct 1126 DLAHEEPRRET 1136
>sp|Q8NAU1|FNDC5_HUMAN Fibronectin type III domain-containing
protein 5 OS=Homo sapiens OX=9606 GN=FNDC5 PE=1 SV=3
Length=212
Score = 54.9 bits (130), Expect = 5e-07, Method: Composition-based stats.
Identities = 26/137 (19%), Positives = 57/137 (42%), Gaps = 9/137 (7%)
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQ 271
+ F V P+ P N++V + + S+++ +W ++ +++ + I + KD
Sbjct 24 VCFALVQADSPSAPVNVTVRHLKANSAVV--SWDV--LEDEVVIGFAISQQKKDVRMLRF 79
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
I +T T S + DL+ TEY+ ++ + G+ S SE T + A
Sbjct 80 IQEVNT--TTRSCALWDLEEDTEYIVHVQAISIQGQ---SPASEPVLFKTPREAEKMASK 134
Query 332 FWYKIDPSHTQGYRTVQ 348
++ + ++
Sbjct 135 NKDEVTMKEMGRNQQLR 151
Score = 53.3 bits (126), Expect = 2e-06, Method: Composition-based stats.
Identities = 35/184 (19%), Positives = 63/184 (34%), Gaps = 29/184 (16%)
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN--ETAVNVD 571
++ PS V + + N AV+ WD L + + + I + V+
Sbjct 29 VQADSPSAPVNVTVRHLKANSAVVSWDVLEDE----VVIGFAISQQKKDVRMLRFIQEVN 84
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE-FTFTTPKFAQ--------------- 615
++ L L DT Y+V + A + +G E F TP+ A+
Sbjct 85 TTTRSCALWDLEEDTEYIVHVQAISIQGQSPASEPVLFKTPREAEKMASKNKDEVTMKEM 144
Query 616 ---GEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPP 672
++ V + + L + + D+IK N P+ +K S + P
Sbjct 145 GRNQQLRTGEVLIIVVVLFMWAGVIALFCRQYDIIKD----NEPNNNKEKTKSASETSTP 200
Query 673 RHNF 676
H
Sbjct 201 EHQG 204
>sp|Q8K3V5|FNDC5_RAT Fibronectin type III domain-containing protein
5 OS=Rattus norvegicus OX=10116 GN=Fndc5 PE=2 SV=2
Length=209
Score = 54.9 bits (130), Expect = 5e-07, Method: Composition-based stats.
Identities = 26/137 (19%), Positives = 57/137 (42%), Gaps = 9/137 (7%)
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQ 271
+ F V P+ P N++V + + S+++ +W ++ +++ + I + KD
Sbjct 21 VCFALVQADSPSAPVNVTVRHLKANSAVV--SWDV--LEDEVVIGFAISQQKKDVRMLRF 76
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
I +T T S + DL+ TEY+ ++ + G+ S SE T + A
Sbjct 77 IQEVNT--TTRSCALWDLEEDTEYIVHVQAISIQGQ---SPASEPVLFKTPREAEKMASK 131
Query 332 FWYKIDPSHTQGYRTVQ 348
++ + ++
Sbjct 132 NKDEVTMKEMGRNQQLR 148
Score = 52.9 bits (125), Expect = 2e-06, Method: Composition-based stats.
Identities = 35/184 (19%), Positives = 63/184 (34%), Gaps = 29/184 (16%)
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN--ETAVNVD 571
++ PS V + + N AV+ WD L + + + I + V+
Sbjct 26 VQADSPSAPVNVTVRHLKANSAVVSWDVLEDE----VVIGFAISQQKKDVRMLRFIQEVN 81
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE-FTFTTPKFAQ--------------- 615
++ L L DT Y+V + A + +G E F TP+ A+
Sbjct 82 TTTRSCALWDLEEDTEYIVHVQAISIQGQSPASEPVLFKTPREAEKMASKNKDEVTMKEM 141
Query 616 ---GEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPP 672
++ V + + L + + D+IK N P+ +K S + P
Sbjct 142 GRNQQLRTGEVLIIVVVLFMWAGVIALFCRQYDIIKD----NEPNNNKEKTKSASETSTP 197
Query 673 RHNF 676
H
Sbjct 198 EHQG 201
>sp|Q8K4Z2|FNDC5_MOUSE Fibronectin type III domain-containing
protein 5 OS=Mus musculus OX=10090 GN=Fndc5 PE=1 SV=1
Length=209
Score = 54.9 bits (130), Expect = 5e-07, Method: Composition-based stats.
Identities = 26/137 (19%), Positives = 57/137 (42%), Gaps = 9/137 (7%)
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQ 271
+ F V P+ P N++V + + S+++ +W ++ +++ + I + KD
Sbjct 21 VCFALVQADSPSAPVNVTVRHLKANSAVV--SWDV--LEDEVVIGFAISQQKKDVRMLRF 76
Query 272 IPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
I +T T S + DL+ TEY+ ++ + G+ S SE T + A
Sbjct 77 IQEVNT--TTRSCALWDLEEDTEYIVHVQAISIQGQ---SPASEPVLFKTPREAEKMASK 131
Query 332 FWYKIDPSHTQGYRTVQ 348
++ + ++
Sbjct 132 NKDEVTMKEMGRNQQLR 148
Score = 52.9 bits (125), Expect = 2e-06, Method: Composition-based stats.
Identities = 35/184 (19%), Positives = 63/184 (34%), Gaps = 29/184 (16%)
Query 514 LKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGN--ETAVNVD 571
++ PS V + + N AV+ WD L + + + I + V+
Sbjct 26 VQADSPSAPVNVTVRHLKANSAVVSWDVLEDE----VVIGFAISQQKKDVRMLRFIQEVN 81
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE-FTFTTPKFAQ--------------- 615
++ L L DT Y+V + A + +G E F TP+ A+
Sbjct 82 TTTRSCALWDLEEDTEYIVHVQAISIQGQSPASEPVLFKTPREAEKMASKNKDEVTMKEM 141
Query 616 ---GEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPP 672
++ V + + L + + D+IK N P+ +K S + P
Sbjct 142 GRNQQLRTGEVLIIVVVLFMWAGVIALFCRQYDIIKD----NEPNNNKEKTKSASETSTP 197
Query 673 RHNF 676
H
Sbjct 198 EHQG 201
>sp|Q568M3|CRLF3_DANRE Cytokine receptor-like factor 3 OS=Danio
rerio OX=7955 GN=crlf3 PE=2 SV=1
Length=444
Score = 56.8 bits (135), Expect = 6e-07, Method: Composition-based stats.
Identities = 23/106 (22%), Positives = 42/106 (40%), Gaps = 8/106 (8%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
V +PP + + E + + W Y +Q+R ++S +
Sbjct 173 VASHPP--VQIEELVERPGGVLVRWCK-VDDDFSPQDYRLQFRRSNSSQYEDAYI----G 225
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
+ F V L P +++FR+ C + +G+ WS WS +G T
Sbjct 226 KDTEFLVLHLDPHVDHLFRV-CARGEGRTEWSPWSIPQTGYTTLAP 270
>sp|Q9Y5Z7|HCFC2_HUMAN Host cell factor 2 OS=Homo sapiens OX=9606
GN=HCFC2 PE=1 SV=1
Length=792
Score = 57.2 bits (136), Expect = 7e-07, Method: Composition-based stats.
Identities = 42/258 (16%), Positives = 76/258 (29%), Gaps = 33/258 (13%)
Query 371 TRWKSHLQNYTVNATKLTVNLTNDRY--LATLTVRNLVGKSDAAVLTIPACDFQATHPVM 428
T S + T LT T L + + + P ++PV
Sbjct 531 TESSSTNGAVVKDETSLTTFSTKSEVDETYALPA-TKISRVETHATATPFSKETPSNPVA 589
Query 429 DLKAFPKDNMLWVEWTTPR--ESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
+KA + +W ++ + ++ +L I+ D + + +L
Sbjct 590 TVKAGER------QWCDVGIFKNNTALVSQFYLLPKGKQSISKVGNADVPDYSLLKKQDL 643
Query 487 AESKCYLITVTPVYADGPGSPESIKAYLK--QAPPSKGPTVRTKKVGKNEAVLEWDQLPV 544
Y V + G G I + P VR K + L W+ P
Sbjct 644 VPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVEG-IHLSWE--PP 700
Query 545 DVQNGFIRNY-----------------TIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTL 587
+G I Y +F R G +T+ V + TS
Sbjct 701 TSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPA 760
Query 588 YMVRMAAYTDEGGKDGPE 605
+ R++A ++G +
Sbjct 761 IVFRISAKNEKGYGPATQ 778
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 26/131 (20%), Positives = 40/131 (31%), Gaps = 15/131 (11%)
Query 192 VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS 251
V A N G I+ P P S + + + L+W P+ S
Sbjct 647 TGYRFRVAAINGCGIGPFSKISEFKTCI--PGFPGAPSAVRISKNVEGIHLSWEPPTSPS 704
Query 252 VIILKYN----IQYRTKDASTWSQIPPEDTASTRSSFTVQD---LKPFTEY------VFR 298
IL+Y+ I+ + + ++S V +Y VFR
Sbjct 705 GNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFR 764
Query 299 IRCMKEDGKGY 309
I E G G
Sbjct 765 ISAKNEKGYGP 775
Score = 51.8 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 33/147 (22%), Positives = 51/147 (35%), Gaps = 31/147 (21%)
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
QDL P T Y FR+ + G G +S SE + I P APS ++
Sbjct 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIP--GFP-GAPSAVRI-----SKNVEG 692
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA----------TKLTV------- 389
+ L W+ PP +G IL+Y L + +Q+ T V
Sbjct 693 IHLSWE--PPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLAN 750
Query 390 ----NLTNDRYLATLTVRNLVGKSDAA 412
+ + ++ +N G A
Sbjct 751 AHIDYTSRPAIVFRISAKNEKGYGPAT 777
Score = 40.6 bits (93), Expect = 0.088, Method: Composition-based stats.
Identities = 19/148 (13%), Positives = 38/148 (26%), Gaps = 21/148 (14%)
Query 391 LTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES 449
+ Y + N G + + C ++ + + W P
Sbjct 644 VPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSP 703
Query 450 VKKYILEWCVLS-------DKAPCITDWQQEDGTVHRTYLR--GNLA-ESKCYL------ 493
ILE+ P + + + + + G LA Y
Sbjct 704 SGN-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIV 762
Query 494 ITVTPVYADGPGSPESIK---AYLKQAP 518
++ G G ++ K+AP
Sbjct 763 FRISAKNEKGYGPATQVRWLQGNNKKAP 790
>sp|P50401|GUXA_CELFA Exoglucanase A OS=Cellulomonas fimi (strain
ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980
/ NCTC 7547) OX=590998 GN=cbhA PE=1 SV=1
Length=872
Score = 57.2 bits (136), Expect = 7e-07, Method: Composition-based stats.
Identities = 49/301 (16%), Positives = 82/301 (27%), Gaps = 36/301 (12%)
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKS 375
G T AP+ + T +V L W N + Y+V R +
Sbjct 468 PVIGGTTPVEDLVAPTV-PTGLTAGTTTATSVPLSWTA---STDNVAVTGYDVY--RGTT 521
Query 376 HLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPK 435
+ + +T Y T+ ++ G AA A T + P
Sbjct 522 LVGTTAATSYTVTGLTPATAYSFTVRAKDAAGNVSAASAAAAATTQSGTVTDTTAPSVPA 581
Query 436 D--------NMLWVEWTTPRESVKK-YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNL 486
+ + WT ++ + + VL T T +Y L
Sbjct 582 GLTAGTTTTTTVPLSWTASTDNAGGSGVAGYEVLRGTTVVGT-------TTATSYTVTGL 634
Query 487 AESKCYLITVTPVYADG--------PGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLE 538
Y +V G + + PS + + L
Sbjct 635 TAGTTYSFSVRAKDVAGNTSAASAAVSATTQTGTVVDTTAPSVPTGLTAGTTTTSSVPLT 694
Query 539 WDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDE 598
W + + Y +F N T + T YT++ L +DT Y + A
Sbjct 695 WTASTDNAGGSGVAGYEVF------NGTTRVATVTSTSYTVTGLAADTAYSFTVKAKDVA 748
Query 599 G 599
G
Sbjct 749 G 749
Score = 52.2 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 64/386 (17%), Positives = 116/386 (30%), Gaps = 46/386 (12%)
Query 74 IPKEQYTIINRT-ASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLP------- 125
IP +Q +R + + + T N GQ + + + + P
Sbjct 416 IPNDQGKRFDRMCDPTFVSPKLNNQLTGATPNAPLAGQWFEEQFVTLVKNAYPVIGGTTP 475
Query 126 ------PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTP 179
P P L+ + W + T + + T A T
Sbjct 476 VEDLVAPTVPTGLTAGTTTATSVPLSWTASTDNVAVTGYDVYR--GTTLVGTTAATSYTV 533
Query 180 TSCTVDYSTVYFVNIEVWVEAENALGKVTS-------DHINFDPVYKVKPNPPHNLSVIN 232
T T V A++A G V++ + P+ P L+
Sbjct 534 TGLTPA------TAYSFTVRAKDAAGNVSAASAAAAATTQSGTVTDTTAPSVPAGLTA-- 585
Query 233 SEELSSILKLTWTNPSIKSVI--ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK 290
++ + L+WT + + + Y + + +T +S+TV L
Sbjct 586 GTTTTTTVPLSWTASTDNAGGSGVAGYEV----------LRGTTVVGTTTATSYTVTGLT 635
Query 291 PFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
T Y F +R G + + A+ T + APS + T +V L
Sbjct 636 AGTTYSFSVRAKDVAGNTSAASAAVSATTQTGTVVDTTAPSV-PTGLTAGTTTTSSVPLT 694
Query 351 WKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD 410
W + YEV + + T + +T + Y T+ +++ G
Sbjct 695 WTASTDNAGGSGVAGYEVF--NGTTRVATVTSTSYTVTGLAADTAYSFTVKAKDVAGNVS 752
Query 411 AAVLTIPACDFQATHPVMDLKAFPKD 436
AA + A AT +K
Sbjct 753 AASAAVSARTQAATSGGCTVKYSASS 778
Score = 49.1 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 46/316 (15%), Positives = 79/316 (25%), Gaps = 43/316 (14%)
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSK----APSFWYKIDPSHTQGYRTVQLVWKTLP 355
R + +G W + G E PS + I P + +
Sbjct 363 RVDRRVHRGAWCNPLGAGIGRFPEATPSGYAASHLDAFVWIKPPGESDGASTDI------ 416
Query 356 PFEANGKILDYEVTLTRWKSHLQNYTVNATK---LTVNLTNDRYLATLT-VRNLVGKSDA 411
P + GK D T L N AT L ++++ + ++G
Sbjct 417 PNDQ-GKRFDRMCDPTFVSPKLNNQLTGATPNAPLAGQWFEEQFVTLVKNAYPVIG---- 471
Query 412 AVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQ 471
T T P + + WT ++V + + V
Sbjct 472 -GTTPVEDLVAPTVPTGLTAGTTTATSVPLSWTASTDNVA--VTGYDVYRGT-------T 521
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTP--------VYADGPGSPESIKAYLKQAPPSKGP 523
T +Y L + Y TV + + PS
Sbjct 522 LVGTTAATSYTVTGLTPATAYSFTVRAKDAAGNVSAASAAAAATTQSGTVTDTTAPSVPA 581
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLT 583
+ L W + + Y + T + T + + LT
Sbjct 582 GLTAGTTTTTTVPLSWTASTDNAGGSGVAGYEVLRGTTVVGTTTATSYTV------TGLT 635
Query 584 SDTLYMVRMAAYTDEG 599
+ T Y + A G
Sbjct 636 AGTTYSFSVRAKDVAG 651
>sp|Q63638|SPEG_RAT Striated muscle-specific serine/threonine-protein
kinase OS=Rattus norvegicus OX=10116 GN=Speg PE=1 SV=2
Length=3259
Score = 57.2 bits (136), Expect = 8e-07, Method: Composition-based stats.
Identities = 61/390 (16%), Positives = 106/390 (27%), Gaps = 30/390 (8%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A N LG +TS K PP + + L L W S Y +
Sbjct 2659 ATNVLGSITSSCTVAVARTPGKLAPPE----VPQTYCDTALVL-WKPGD--SRAPCTYTL 2711
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ R S W P + + V L FR+ C G+G +S+ SE+
Sbjct 2712 ERRVDGESVWH---PVSSGIPDCYYNVTQLPVGVTVRFRVACSNRAGQGPFSNPSEKVFI 2768
Query 320 ITYED-------RPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTR 372
+D P AP ++ PP T
Sbjct 2769 RGTQDSPAQSAAAPRDAPVTSGPTRAPPPDSPTSLV----PTPPLAPQVSQASTLSPSTS 2824
Query 373 WKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKA 432
S Q + T R L S ++L P+ L
Sbjct 2825 SMSANQALSSLKAVGPPPATPPRKHRGLLATQQAEPSPPSILVTPSEHKSFVPDTGTLTP 2884
Query 433 FPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
+ S Y++ V + P + T L+ +K
Sbjct 2885 TSSPQGV----KPAPSSSSLYMVTSFVSAPPDPQPPAPEPPPEPTKVTVRS--LSPAKEV 2938
Query 493 LITVTPVYAD-GPGSPESIKAYLKQAPPSKGPTVRT--KKVGKNEAVLEWDQLPVDVQNG 549
+ + TP G P+ +L++ + VR+ + V + + +
Sbjct 2939 VSSPTPESTTLRQGPPQKPYTFLEEKARGRFGVVRSCRENATGRTFVAKIVPYAAEGKRR 2998
Query 550 FIRNYTIFYRTIIGNETAVNVDSSHTEYTL 579
++ Y + +++ Y +
Sbjct 2999 VLQEYEVLRTLHHERLMSLHEAYITPRYLV 3028
Score = 44.8 bits (104), Expect = 0.005, Method: Composition-based stats.
Identities = 32/174 (18%), Positives = 55/174 (32%), Gaps = 25/174 (14%)
Query 200 AENALGKVTS-DHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSVII--- 254
N LGK H+ V P+ P ++V ++ L+W P + I
Sbjct 1267 IANKLGKAACYAHLYVTDVVPGPPDGAPQVVAV-----TGRMVTLSWNPPRSLDMAIDPD 1321
Query 255 -LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
L Y +Q++ + W+ + T + LK ++FR+ S
Sbjct 1322 SLTYTVQHQVLGSDQWTAL---VTGLREPEWAATGLKKGLHHIFRVLSSSGKSSSKPSAP 1378
Query 314 SEEA----SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ-------LVWKTLPP 356
SE G E+ P+ TV +VW++
Sbjct 1379 SEPVQLLEHGPPLEEAPAVLDKQDIVYVVEGQPACVTVTFNHVEAQVVWRSCRG 1432
>sp|O02744|IL12B_FELCA Interleukin-12 subunit beta OS=Felis catus
OX=9685 GN=IL12B PE=2 SV=1
Length=329
Score = 55.6 bits (132), Expect = 9e-07, Method: Composition-based stats.
Identities = 40/206 (19%), Positives = 69/206 (33%), Gaps = 35/206 (17%)
Query 132 LSCIV-NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVY 190
L C N + C W T L FT+KS + + T ++ V
Sbjct 129 LKCEAKNYSGRFTCWWLTAISTDL--KFTVKSSRGSSDPQEVTCGAATLSAEKVRVDNRD 186
Query 191 FVNIEVW-------------------VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVI 231
+ V V+A + L K + +F +KP+PP NL +
Sbjct 187 YKKYTVECQEGSACPAAEESLPIEVVVDAIHKL-KYENYTSSFFIRDIIKPDPPKNLQLK 245
Query 232 NSEELSSILKLTWTNP----SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
+ S ++++W P + S L + +Q + K+ D S + +
Sbjct 246 PL-KNSRHVEVSWEYPDTWSTPHSYFSLTFGVQVQGKNNREKKDRLSVDKTSAKVVCH-K 303
Query 288 DLKPFTEYVFRIRCMKEDGKGYWSDW 313
D K R++ WS+W
Sbjct 304 DAK------IRVQARDRYYSSSWSNW 323
>sp|M9MRI4|TRIM9_DROME E3 ubiquitin-protein ligase TRIM9 OS=Drosophila
melanogaster OX=7227 GN=Trim9 PE=1 SV=1
Length=740
Score = 56.8 bits (135), Expect = 9e-07, Method: Composition-based stats.
Identities = 16/96 (17%), Positives = 29/96 (30%), Gaps = 8/96 (8%)
Query 515 KQAPPSKGPTVRTK----KVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
+ P+ T N + W + F+ Y + G E
Sbjct 468 DERCPAAPMTPTILPSDCSAENNSVTVAWQPP----NHSFVEGYVLELDDGSGGEFREVY 523
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF 606
T T+ L +++Y R+ A+ G + E
Sbjct 524 CGKETICTVDGLHFNSMYNARVKAFNSAGEGEYSEL 559
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 21/131 (16%), Positives = 46/131 (35%), Gaps = 18/131 (14%)
Query 222 PNPPHNLSVINSE--ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
P P +++ S+ ++ + + W P + Y ++ + ++
Sbjct 472 PAAPMTPTILPSDCSAENNSVTVAWQPP--NHSFVEGYVLELDDGSGGEFREVYC----G 525
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
+ TV L + Y R++ G+G ++SE T E W+ DP
Sbjct 526 KETICTVDGLHFNSMYNARVKAFNSAGEG---EYSELIGLQTAEVA-------WFTFDPV 575
Query 340 HTQGYRTVQLV 350
+ G + +
Sbjct 576 LSGGAGSGLIF 586
Score = 43.7 bits (101), Expect = 0.008, Method: Composition-based stats.
Identities = 34/206 (17%), Positives = 57/206 (28%), Gaps = 29/206 (14%)
Query 372 RWKSHLQNYTVNATKLTVNLTNDRYLAT-LTVRNLVGKSDAAVLTIPACDFQATHPVMDL 430
W + N + + +D LA + N + + + D + M
Sbjct 424 TWHQEVTNAAPRVSPIVDLTLDDAALARAIDNLNFI-----QMRAVKDGDERCPAAPMTP 478
Query 431 KAFPKD-----NMLWVEWTTPRES-VKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
P D N + V W P S V+ Y+LE ++++
Sbjct 479 TILPSDCSAENNSVTVAWQPPNHSFVEGYVLE-----LDDGSGGEFREVYCGKETICTVD 533
Query 485 NLAESKCYLITVTPVYADGPGSPESIKAY-LKQ------APPSKGPTVRTKKVGKNEAVL 537
L + Y V + G G + + P G KN A +
Sbjct 534 GLHFNSMYNARVKAFNSAGEGEYSELIGLQTAEVAWFTFDPVLSGGAGSGLIFSKNNATV 593
Query 538 E---WDQLPVDVQNGFIRNYTIFYRT 560
W+ GF R + Y
Sbjct 594 SVEGWEHRVALGSVGFSRG--VHYWE 617
>sp|Q8I7I5|ROL3_CAEEL Protein roller-3 OS=Caenorhabditis elegans
OX=6239 GN=rol-3 PE=1 SV=2
Length=2481
Score = 56.8 bits (135), Expect = 9e-07, Method: Composition-based stats.
Identities = 57/371 (15%), Positives = 94/371 (25%), Gaps = 73/371 (20%)
Query 192 VNIEVWVEAEN--ALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSI 249
+ +V V N + S +F P+ P + I + L W P
Sbjct 1511 TDYDVTVTWLNRYSPASGVSASKSFR-TGFGYPSAPRDPHAI--PVTPDTVYLYWNLPET 1567
Query 250 KSVIILKYNIQYRTKDASTWSQIPPE------------DTASTRSSFTVQ-------DLK 290
+ I I+Y+ + +P + +S +S + +L+
Sbjct 1568 LNAPIS--EIKYKISQQAAGISVPTSIAVIALSETVSSNISSDTTSCLINPCRVKIANLR 1625
Query 291 PFTEYVFRIRCMKEDGKGYWS------DWSEEASGITYEDRPSKAPSFWYKIDPSHTQGY 344
P EY F + + S EA T D P + P + G
Sbjct 1626 PSNEYKFWVTATHISHLDAATILKDDDAVSSEAVARTL-DVPGT-------LRPDNVTGS 1677
Query 345 RTVQLVWKTLPPFEANGKI-LDYEVTLT---RWK-----SHLQNYTVNATKLTVNLTNDR 395
++ L W L P I + Y + W+ S + T +T L+
Sbjct 1678 -SLLLRWNGLEPEHRPSSIAVQYRESGGANNEWQFPMNVSFEPDVTTELVPITNLLSATS 1736
Query 396 YLATLTV-RNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNML----------WVEWT 444
Y D VL Q P V W
Sbjct 1737 YDYRFVATYTGTYTIDGKVLAFKEDYLQLPQQARTKAGVPTAPQFVEAKQDEEGWIVTWK 1796
Query 445 TPRESVKKYIL------------EWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCY 492
P I EW + W + + + + E +
Sbjct 1797 EPMSDGGSPITSYAVETRINKTAEWEIAERGLDGWKTWWRPGKSDTTSSTSTSSTEVSEF 1856
Query 493 LITVTPVYADG 503
I + G
Sbjct 1857 RIRAANIEGFG 1867
Score = 51.0 bits (120), Expect = 6e-05, Method: Composition-based stats.
Identities = 24/135 (18%), Positives = 37/135 (27%), Gaps = 25/135 (19%)
Query 484 GNLAESKCYLITVTPVYADGP--GSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
G L + Y +TVT + P G S PS V + L W+
Sbjct 1505 GILDKETDYDVTVTWLNRYSPASGVSASKSFRTGFGYPSAPRDPHAIPVTPDTVYLYWNL 1564
Query 542 LPVDVQNGFI--RNYTIFYRTII------------GNETAVNVDSSHTE-------YTLS 580
+ N I Y I + + N+ S T ++
Sbjct 1565 --PETLNAPISEIKYKISQQAAGISVPTSIAVIALSETVSSNISSDTTSCLINPCRVKIA 1622
Query 581 SLTSDTLYMVRMAAY 595
+L Y + A
Sbjct 1623 NLRPSNEYKFWVTAT 1637
Score = 47.5 bits (111), Expect = 7e-04, Method: Composition-based stats.
Identities = 38/221 (17%), Positives = 74/221 (33%), Gaps = 20/221 (9%)
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
+ + + L+ T + P ++ K +I +R K Q PP T + ++FT+
Sbjct 950 EIKFIDGSKTNLQWTLSPPLEAGTVLFKVSI-FREKMGG---QDPPIITIQSETNFTIPS 1005
Query 289 --LKPFT---EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK--IDPSHT 341
L+ ++ + ++ M W+ +G+T +P +P+
Sbjct 1006 EVLEAWSSAQRFDVSVQAMT-----PWATAVLNRTGLTAPVKPPTSPTQLRIFATQQKTV 1060
Query 342 QGYRTVQ-LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL 400
G R + W PP E NG Y V T+ V ++ + +
Sbjct 1061 DGPRALISFFW--GPPSEWNGTPYQYIVNCTKDDGSWIGGPVTTSQSHYSFAVKSGKVSC 1118
Query 401 -TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW 440
+ + + D P++ L A N L
Sbjct 1119 QAAAANEPTNIGSFSELITIDSSELKPLVKLFAIDSTNSLI 1159
>sp|Q5RKG2|HCFC2_RAT Host cell factor 2 OS=Rattus norvegicus OX=10116
GN=Hcfc2 PE=2 SV=1
Length=723
Score = 56.4 bits (134), Expect = 1e-06, Method: Composition-based stats.
Identities = 28/171 (16%), Positives = 53/171 (31%), Gaps = 22/171 (13%)
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
+ ++ +L ++ D + + +L Y V + G G + +
Sbjct 542 VSQFYLLPKGKQSMSKVGNADVPDYSLLKKQDLVPGTVYKFRVAAINGCGIGPFSKLSEF 601
Query 514 LK--QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY----------------- 554
P TVR K + L W+ P +G I Y
Sbjct 602 KTCIPGFPGAPSTVRISKNVEG-IHLSWE--PPTSPSGNILEYSAYLAIRTAQVQDNPSQ 658
Query 555 TIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+F R G +T+ V + TS + R++A ++G +
Sbjct 659 LVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQ 709
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 33/147 (22%), Positives = 51/147 (35%), Gaps = 31/147 (21%)
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
QDL P T Y FR+ + G G +S SE + I P APS ++
Sbjct 572 QDLVPGTVYKFRVAAINGCGIGPFSKLSEFKTCIP--GFP-GAPSTVRI-----SKNVEG 623
Query 347 VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNA----------TKLTV------- 389
+ L W+ PP +G IL+Y L + +Q+ T V
Sbjct 624 IHLSWE--PPTSPSGNILEYSAYLAIRTAQVQDNPSQLVFMRIYCGLKTSCIVTAGQLAN 681
Query 390 ----NLTNDRYLATLTVRNLVGKSDAA 412
+ + ++ +N G A
Sbjct 682 AHIDYTSRPAIVFRISAKNEKGYGPAT 708
Score = 51.8 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 26/132 (20%), Positives = 43/132 (33%), Gaps = 17/132 (13%)
Query 192 VNIEVWVEAENALGKVTSDHIN-FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+ V A N G ++ F P P + + + E + L+W P+
Sbjct 578 TVYKFRVAAINGCGIGPFSKLSEFKTCIPGFPGAPSTVRISKNVEG---IHLSWEPPTSP 634
Query 251 SVIILKYN----IQYRTKDASTWSQIPPEDTASTRSSFTVQD---LKPFTEY------VF 297
S IL+Y+ I+ + + ++S V +Y VF
Sbjct 635 SGNILEYSAYLAIRTAQVQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVF 694
Query 298 RIRCMKEDGKGY 309
RI E G G
Sbjct 695 RISAKNEKGYGP 706
Score = 43.3 bits (100), Expect = 0.013, Method: Composition-based stats.
Identities = 19/148 (13%), Positives = 38/148 (26%), Gaps = 21/148 (14%)
Query 391 LTNDRYLATLTVRNLVGKSDAA-VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES 449
+ Y + N G + + C ++ + + W P
Sbjct 575 VPGTVYKFRVAAINGCGIGPFSKLSEFKTCIPGFPGAPSTVRISKNVEGIHLSWEPPTSP 634
Query 450 VKKYILEWC-------VLSDKAPCITDWQQEDGTVHRTYLR--GNLA-ESKCYL------ 493
ILE+ P + + + + + G LA Y
Sbjct 635 SGN-ILEYSAYLAIRTAQVQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIV 693
Query 494 ITVTPVYADGPGSPESIK---AYLKQAP 518
++ G G ++ K+AP
Sbjct 694 FRISAKNEKGYGPATQVRWLQGNSKKAP 721
>sp|P68220|IL12B_SHEEP Interleukin-12 subunit beta OS=Ovis aries
OX=9940 GN=IL12B PE=1 SV=1
Length=327
Score = 55.2 bits (131), Expect = 1e-06, Method: Composition-based stats.
Identities = 42/246 (17%), Positives = 87/246 (35%), Gaps = 43/246 (17%)
Query 100 QLTCN---------ILTFGQLEQNVYGITIISG-LPPEKPKNLSCIVNEGKK-MRCEWDG 148
Q TC+ +L + E ++ I+ P+ L C + C W
Sbjct 87 QYTCHKGGEVLSRSLLLLHKKEDGIWSTDILKDQKEPKAKSFLKCEAKDYSGHFTCSWLT 146
Query 149 GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN--------------- 193
T+L+ + + + C A + ++D+
Sbjct 147 AISTNLKFSVKSSRGSSDPRGVTCGAASLSAEKVSMDHREYNKYTVECQEGSACPAAEES 206
Query 194 --IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP---- 247
IEV +EA + L K + +F +KP+PP NL + + S ++++W P
Sbjct 207 LPIEVVMEAVHKL-KYENYTSSFFIRDIIKPDPPKNLQLRPL-KNSRQVEVSWEYPDTWS 264
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
+ S L + +Q + K+ ++ + T++ + + R++
Sbjct 265 TPHSYFSLTFCVQVQGKNKRE-KKLFTDQTSAKVTCHKDAN--------IRVQARDRYYS 315
Query 308 GYWSDW 313
+WS+W
Sbjct 316 SFWSEW 321
>sp|P68221|IL12B_CAPHI Interleukin-12 subunit beta OS=Capra hircus
OX=9925 GN=IL12B PE=2 SV=1
Length=327
Score = 55.2 bits (131), Expect = 1e-06, Method: Composition-based stats.
Identities = 42/246 (17%), Positives = 87/246 (35%), Gaps = 43/246 (17%)
Query 100 QLTCN---------ILTFGQLEQNVYGITIISG-LPPEKPKNLSCIVNEGKK-MRCEWDG 148
Q TC+ +L + E ++ I+ P+ L C + C W
Sbjct 87 QYTCHKGGEVLSRSLLLLHKKEDGIWSTDILKDQKEPKAKSFLKCEAKDYSGHFTCSWLT 146
Query 149 GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN--------------- 193
T+L+ + + + C A + ++D+
Sbjct 147 AISTNLKFSVKSSRGSSDPRGVTCGAASLSAEKVSMDHREYNKYTVECQEGSACPAAEES 206
Query 194 --IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP---- 247
IEV +EA + L K + +F +KP+PP NL + + S ++++W P
Sbjct 207 LPIEVVMEAVHKL-KYENYTSSFFIRDIIKPDPPKNLQLRPL-KNSRQVEVSWEYPDTWS 264
Query 248 SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
+ S L + +Q + K+ ++ + T++ + + R++
Sbjct 265 TPHSYFSLTFCVQVQGKNKRE-KKLFTDQTSAKVTCHKDAN--------IRVQARDRYYS 315
Query 308 GYWSDW 313
+WS+W
Sbjct 316 SFWSEW 321
>sp|P26951|IL3RA_HUMAN Interleukin-3 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL3RA PE=1 SV=1
Length=378
Score = 55.2 bits (131), Expect = 1e-06, Method: Composition-based stats.
Identities = 37/207 (18%), Positives = 69/207 (33%), Gaps = 22/207 (11%)
Query 121 ISGLPPEKPKNLSCIVNEGKKMRCEWD--GGRETHLETNFTLKSEWATHKFADCKAKRDT 178
SG P +NL+C +++ + C W G ++ + L ++ K D
Sbjct 99 NSGKPWAGAENLTCWIHDVDFLSCSWAVGPGAPADVQYDLYLNVANRRQQYECLHYKTDA 158
Query 179 P---TSCTVD---YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
C D + + + V +A + PP N++
Sbjct 159 QGTRIGCRFDDISRLSSGSQSSHILVRGRSAAFGIPCTDKFVVFSQIEILTPP-NMTAKC 217
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
++ S + W S + +Y +Q + ++ P T R + Q L P
Sbjct 218 NKTHS---FMHWKMRSHFNRKF-RYELQIQ-------KRMQPVITEQVRDRTSFQLLNPG 266
Query 293 TEYVFRIRCMKEDGKGYWSDWSEEASG 319
T Y +IR + + + S WS
Sbjct 267 T-YTVQIRARERVYE-FLSAWSTPQRF 291
>sp|Q7ZX59|CRLF3_XENLA Cytokine receptor-like factor 3 OS=Xenopus
laevis OX=8355 GN=crlf3 PE=2 SV=1
Length=436
Score = 55.6 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 26/103 (25%), Positives = 41/103 (40%), Gaps = 8/103 (8%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
V PP + + E + + W + Y +QYR AS + +
Sbjct 173 VASRPP--VQIEELIERPGAILVKWCK-CDDDFVAQDYRLQYRKNTASHFEDVY----VG 225
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ S F V + P +Y FR+ C + DG+ WS WS + T
Sbjct 226 SESEFIVLQIDPNVDYQFRV-CARGDGRQEWSPWSVLQTSRTT 267
Score = 42.9 bits (99), Expect = 0.011, Method: Composition-based stats.
Identities = 15/94 (16%), Positives = 35/94 (37%), Gaps = 5/94 (5%)
Query 519 PSKGPTVRTKKV--GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
+ P V+ +++ +++W + D ++Y + YR + S +E
Sbjct 173 VASRPPVQIEELIERPGAILVKWCKCDDDF---VAQDYRLQYRKNTASHFEDVYVGSESE 229
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ + + + Y R+ A D + P T
Sbjct 230 FIVLQIDPNVDYQFRVCARGDGRQEWSPWSVLQT 263
>sp|Q865W9|IL12B_LAMGL Interleukin-12 subunit beta OS=Lama glama
OX=9844 GN=IL12B PE=2 SV=1
Length=330
Score = 54.9 bits (130), Expect = 2e-06, Method: Composition-based stats.
Identities = 35/209 (17%), Positives = 69/209 (33%), Gaps = 29/209 (14%)
Query 126 PEKPKNLSCIV-NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTV 184
P+ L C N C W T L+ + + + C A + V
Sbjct 124 PKSKTFLKCEAKNYSGHFTCWWLTAVSTDLKFSVKSSRGSSDPRGVTCGAATLSAERVGV 183
Query 185 DYSTVYFVN-----------------IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHN 227
++ + IE+ VEA + L K + +F ++P+PP N
Sbjct 184 EHRDSWKYTVECQEGSSCPAAEESLPIELVVEAVHKL-KYENYSSSFFIRDIIRPDPPKN 242
Query 228 LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ 287
L + + S ++++W P S +++ + + + + ++S V
Sbjct 243 LQLKPL-KNSRHVEVSWEYPDTWSTPHSYFSLTFCVQVQGKHKREKKDKLFVDQTSAKVT 301
Query 288 ---DLKPFTEYVFRIRCMKEDGKGYWSDW 313
D R++ WS+W
Sbjct 302 CPKDAS------IRVQARDRYYSSSWSEW 324
>sp|Q8WUT4|LRRN4_HUMAN Leucine-rich repeat neuronal protein 4
OS=Homo sapiens OX=9606 GN=LRRN4 PE=1 SV=3
Length=740
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 26/135 (19%), Positives = 42/135 (31%), Gaps = 10/135 (7%)
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
P+PP V +E + + W P + ++ Y I+Y + + +
Sbjct 576 EDTIPDPPRLQGV--TETTDTSALVHWCAP---NSVVHGYQIRYSAEGWAGNQSVVGV-I 629
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYW--SDWSEEASGITYEDRPSKAPSFWYK 335
+T + L P T Y + G S W + T +PS A
Sbjct 630 YATARQHPLYGLSPGTTYRVCVLAANRAGLSQPRSSGWRSPCAAFTT--KPSFALLLSGL 687
Query 336 IDPSHTQGYRTVQLV 350
S TV L
Sbjct 688 CAASGLLLASTVVLS 702
Score = 54.1 bits (128), Expect = 5e-06, Method: Composition-based stats.
Identities = 27/147 (18%), Positives = 45/147 (31%), Gaps = 15/147 (10%)
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII--GNETAVNVD- 571
+ P + A++ W N + Y I Y GN++ V V
Sbjct 576 EDTIPDPPRLQGVTETTDTSALVHW-----CAPNSVVHGYQIRYSAEGWAGNQSVVGVIY 630
Query 572 SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD-------GPEFTFTTPKFAQGEIEAIVVP 624
++ ++ L L+ T Y V + A G P FTT + +
Sbjct 631 ATARQHPLYGLSPGTTYRVCVLAANRAGLSQPRSSGWRSPCAAFTTKPSFALLLSGLCAA 690
Query 625 VCLAFLLTTLLGVLFCFNKRDLIKKHI 651
L T +L C + L +
Sbjct 691 SGLLLASTVVLSACLCRRGQTLGLQRC 717
Score = 41.8 bits (96), Expect = 0.034, Method: Composition-based stats.
Identities = 17/112 (15%), Positives = 26/112 (23%), Gaps = 2/112 (2%)
Query 416 IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDG 475
+ D P + D V W P V Y + +
Sbjct 573 LSGEDTIPDPPRLQGVTETTDTSALVHWCAPNSVVHGYQIRYSAEGWAGNQ--SVVGVIY 630
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
R + L+ Y + V G P S A + P+
Sbjct 631 ATARQHPLYGLSPGTTYRVCVLAANRAGLSQPRSSGWRSPCAAFTTKPSFAL 682
>sp|Q62407|SPEG_MOUSE Striated muscle-specific serine/threonine-protein
kinase OS=Mus musculus OX=10090 GN=Speg PE=1 SV=2
Length=3262
Score = 56.0 bits (133), Expect = 2e-06, Method: Composition-based stats.
Identities = 42/253 (17%), Positives = 71/253 (28%), Gaps = 33/253 (13%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A N LG +TS K PP + L + W Y +
Sbjct 2662 ATNVLGSITSSCTVAVARIPGKLAPPEVPQTYHDTAL-----VVWKPGD--GRAPCTYTL 2714
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ R S W P + + V L FR+ C G+G +S+ SE+
Sbjct 2715 ERRVDGESVWH---PVSSGIPDCYYNVTQLPVGVTVRFRVACSNRAGQGPFSNPSEKVFI 2771
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN 379
D P++ P+ + P + R PP +
Sbjct 2772 RGTPDSPAQ-PAAAPRDAPVTSGPTRA-------PPPDSP------------TSLAPTPA 2811
Query 380 YTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNML 439
A++ + + ++ + + T P +A P +
Sbjct 2812 LAPPASQASTLSPSTSSMSANQALSSLKAVGPPPATPPRKHRGLLATQ---QAEPSPPSI 2868
Query 440 WVEWTTPRESVKK 452
V + PR V
Sbjct 2869 VVTPSEPRSFVPD 2881
Score = 46.0 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 43/256 (17%), Positives = 80/256 (31%), Gaps = 32/256 (13%)
Query 200 AENALGKVTS-DHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSVII--- 254
N LGK H+ V P+ P ++V ++ L+W P + I
Sbjct 1267 IANKLGKAACYAHLYVTDVVPGPPDGAPEVVAV-----TGRMVTLSWNPPRSLDMAIDPD 1321
Query 255 -LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
L Y +Q++ + W+ + T ++ LK +++FR+ S
Sbjct 1322 SLTYTVQHQVLGSDQWTAL---VTGLREPAWAATGLKKGIQHIFRVLSSSGKSSSKPSAP 1378
Query 314 SEEA----SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ-------LVWKTLPPFEANGK 362
SE G E+ P+ TV +VW++ +
Sbjct 1379 SEPVQLLEHGPPLEEAPAVLDKQDIVYVVEGQPACVTVTFNHVEAQVVWRSCRGALLEAR 1438
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
YE++ + + D T + RN G +V A +
Sbjct 1439 TGVYELSQPDDDQYCLRICRVS-------RRDLGPLTCSARNRHGTKACSVTLELAEAPR 1491
Query 423 ATHPVMDLKAFPKDNM 438
+ D++ P +
Sbjct 1492 FESIMEDVEVGPGETA 1507
>sp|Q8CJE6|IL12B_MESAU Interleukin-12 subunit beta OS=Mesocricetus
auratus OX=10036 GN=IL12B PE=2 SV=1
Length=327
Score = 54.9 bits (130), Expect = 2e-06, Method: Composition-based stats.
Identities = 43/227 (19%), Positives = 73/227 (32%), Gaps = 32/227 (14%)
Query 109 GQLEQNVYGITIISGLPPEKPKN---LSCIV-NEGKKMRCEWDGGRETHLETNFTLKSEW 164
+ E ++ I+ + PKN L C N + C W T L+ N S
Sbjct 105 HKKENGIWSTDILKDQ--KDPKNKTFLKCEAANYSGRFTCWWLTAISTDLKFNVKSSSSS 162
Query 165 ATHKFADCKAKRDTPTSCTVDYSTVYFVNIEV---------WVEAENALGKVTSDHIN-- 213
+ + C A + TVD + V E +G V
Sbjct 163 SDSRAVTCGAASLSAEKVTVDRKD--YQKYSVACQEDITCPTAEETLPIGLVMEAQHKYK 220
Query 214 -------FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA 266
F +KP+PP NL + S ++L+W P S +++++ +
Sbjct 221 YENYSTGFFIRDIIKPDPPKNLQLK--PLRGSQMELSWEYPDSWSTPHSYFSLKFHVQVH 278
Query 267 STWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ ++S T++ E R+R WS W
Sbjct 279 RKRERKDESQFVD-KTSATIR-CSKGAE--VRVRAQDHYYNSSWSRW 321
>sp|Q01114|IL9R_MOUSE Interleukin-9 receptor OS=Mus musculus OX=10090
GN=Il9r PE=1 SV=1
Length=468
Score = 55.2 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 37/223 (17%), Positives = 73/223 (33%), Gaps = 29/223 (13%)
Query 132 LSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS---- 187
+C+ N ++ C W + L + + + CT+
Sbjct 53 FTCLSNSIYRIDCHWSAPELGQESRAWLLFTSNQVTEIK--HKCTFWDSMCTLVLPKEEV 110
Query 188 TVYFVNIEVW----VEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
+ F N + + + + V S ++ + K +PP +L S S LT
Sbjct 111 FLPFDNFTITLHRCIMGQEQVSLVDSQYLPRRHI---KLDPPSDLQ---SNVSSGRCVLT 164
Query 244 W--TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
W + L Y + ++ ++ + ++ T +L P + Y R+R
Sbjct 165 WGINLALEPLITSLSYELAFKRQEEAWEARHKDRIVGVTWLILEAVELNPGSIYEARLRV 224
Query 302 MK-----------EDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
E K +WS+WS+ S + + R W
Sbjct 225 QMTLESYEDKTEGEYYKSHWSEWSQPVSFPSPQRRQGLLVPRW 267
>sp|Q91ZK7|IL12B_SIGHI Interleukin-12 subunit beta OS=Sigmodon
hispidus OX=42415 GN=IL12B PE=2 SV=1
Length=327
Score = 54.5 bits (129), Expect = 2e-06, Method: Composition-based stats.
Identities = 49/231 (21%), Positives = 83/231 (36%), Gaps = 40/231 (17%)
Query 109 GQLEQNVYGITIISGLPPEKPKN---LSCIV-NEGKKMRCEWDGGRETHLETNFTLKSEW 164
+ E ++ I+ + PKN L C N + C W T L+ + S
Sbjct 105 HKKEDGIWSTDILKDQ--KDPKNKTFLKCEAANYSGRFTCWWLTAVSTDLKFSLKSSSSS 162
Query 165 ATHKFADCKAKRDTPTSCTVDY-----------------STVYFVNIEVWVEAENALGKV 207
+ + C A + TVD + + IE+ +EA++ K
Sbjct 163 SDSRSVTCGAASLSTEKVTVDQRDYNKYSVACQEDITCPTAEETLPIELVMEAQHKY-KY 221
Query 208 TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP----SIKSVIILKYNIQ-YR 262
+ F +KP+PP NL + SS ++++W P + S LK+ +Q YR
Sbjct 222 ENYSTGFFIRDIIKPDPPKNLQLK--PLKSSQVEVSWEYPDSWSTPHSYFSLKFFVQVYR 279
Query 263 TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
K+ S + D S + + R+R WS+W
Sbjct 280 KKEKKGESLL--VDKPSAKIRCSKGG-------EVRVRAQDHYYNSSWSEW 321
>sp|P06800|PTPRC_MOUSE Receptor-type tyrosine-protein phosphatase
C OS=Mus musculus OX=10090 GN=Ptprc PE=1 SV=4
Length=1293
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 43/267 (16%), Positives = 84/267 (31%), Gaps = 25/267 (9%)
Query 157 NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDP 216
++ L E + + P C +D + N E G ++
Sbjct 315 SYVLHCEPENNT-KCIRRNTFIPERCQLD-NLRAQTNYTCVAEILYR-GVKLVKNVINVQ 371
Query 217 VYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS---VIILKYNIQYRTKDASTWSQIP 273
P P + + ++W P K Y + Y+
Sbjct 372 TDLGIPETPKP---SCGDPAARKTLVSWPEPVSKPESASKPHGYVLCYKNNSE------K 422
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFW 333
+ + +SF V+ LKP+ Y + +GK + +E+ + T DRP K
Sbjct 423 CKSLPNNVTSFEVESLKPYKYYEVSLLAY-VNGKIQRNGTAEKCNFHTKADRPDK----- 476
Query 334 YKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT- 392
+ ++ + PP+E NG Y + + S + Y + V+
Sbjct 477 VNGMKTSRPTDNSINVT--CGPPYETNGPKTFYILVVRSGGSFVTKYNKTNCQFYVDNLY 534
Query 393 -NDRYLATLTVRNLVGKSDAAVLTIPA 418
+ Y ++ N V + D+ +
Sbjct 535 YSTDYEFLVSFHNGVYEGDSVIRNEST 561
Score = 42.2 bits (97), Expect = 0.030, Method: Composition-based stats.
Identities = 14/78 (18%), Positives = 29/78 (37%), Gaps = 5/78 (6%)
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIR--NYTIFYRTIIGNETAVNVDSSHTEYTLS 580
P + ++ W PV + Y + Y+ +E ++ ++ T + +
Sbjct 380 PKPSCGDPAARKTLVSW-PEPVSKPESASKPHGYVLCYK--NNSEKCKSLPNNVTSFEVE 436
Query 581 SLTSDTLYMVRMAAYTDE 598
SL Y V + AY +
Sbjct 437 SLKPYKYYEVSLLAYVNG 454
>sp|V5JFY4|INRA2_ONCMY Interferon alpha/beta receptor 2 OS=Oncorhynchus
mykiss OX=8022 GN=ifnar2 PE=2 SV=1
Length=268
Score = 53.7 bits (127), Expect = 3e-06, Method: Composition-based stats.
Identities = 40/214 (19%), Positives = 71/214 (33%), Gaps = 21/214 (10%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
P N+S + + W G ET T+FT++S + + K T + D +
Sbjct 20 APTNVSIVSFNLEH-TLTWLPGPETPDNTHFTVQS-LRKNSWQLVKGCARLKTRQSCDLT 77
Query 188 TVY---FVNIEVWVEAENALGKV-TSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLT 243
+ F + + V+A K S + F P+ PP V++ + L
Sbjct 78 NTFKDPFYHYKARVQAITTTQKSNRSLSMLFYPLTDTLLGPP----VVSVSGCGNCPLLQ 133
Query 244 WTNPSIKS-----VIILKY--NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYV 296
T P+ + Y + + SQ T++ ++ + L+P EY
Sbjct 134 VTPPTSRGLQRSLSPTQLYYRQFTCKVRRTRDGSQFSMWVTSTEKT--VIGYLEPGAEYC 191
Query 297 FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
+ S SE T + P
Sbjct 192 VTV--TPSTSFNPHSVPSEPHCAFTSPTAANTVP 223
>sp|Q28268|IL12B_CANLF Interleukin-12 subunit beta OS=Canis lupus
familiaris OX=9615 GN=IL12B PE=2 SV=1
Length=329
Score = 54.1 bits (128), Expect = 3e-06, Method: Composition-based stats.
Identities = 46/245 (19%), Positives = 83/245 (34%), Gaps = 39/245 (16%)
Query 100 QLTCN---------ILTFGQLEQNVYGITIISGLPPEKPKN-LSCIV-NEGKKMRCEWDG 148
Q TC+ +L + E ++ I+ K K L C N + C W
Sbjct 87 QYTCHKGGKVLSRSLLLIHKKEDGIWSTDILKEQKESKNKIFLKCEAKNYSGRFTCWWLT 146
Query 149 GRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVN--------------- 193
T L+ + ++ + C A + VD
Sbjct 147 AISTDLKFSVKSSRGFSDPQGVTCGAVTLSAERVRVDNRDYKKYTVECQEGSACPSAEES 206
Query 194 --IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS 251
IEV V+A + L K + +F +KP+PP NL + + S ++++W P S
Sbjct 207 LPIEVVVDAIHKL-KYENYTSSFFIRDIIKPDPPTNLQLKPL-KNSRHVEVSWEYPDTWS 264
Query 252 VIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQ---DLKPFTEYVFRIRCMKEDGKG 308
+++ + + ++ + ++S V D K R++
Sbjct 265 TPHSYFSLTFCVQAQGKNNREKKDRLCVDKTSAKVVCHKDAK------IRVQARDRYYSS 318
Query 309 YWSDW 313
WSDW
Sbjct 319 SWSDW 323
>sp|Q9HC73|CRLF2_HUMAN Cytokine receptor-like factor 2 OS=Homo
sapiens OX=9606 GN=CRLF2 PE=1 SV=1
Length=371
Score = 54.5 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 38/209 (18%), Positives = 71/209 (34%), Gaps = 28/209 (13%)
Query 135 IVNEGKKMRCEWDGGR--ETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFV 192
I + ++ W+ + T+L ++ + A + + + + C +D +
Sbjct 35 IYFNLETVQVTWNASKYSRTNLTFHYRFNGDEAYDQCTNYLLQEGHTSGCLLDAEQRDDI 94
Query 193 NIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSV 252
N G + VY +KP+ P ++ + +T ++ S
Sbjct 95 LY---FSIRN--GTHPVFTASRWMVYYLKPSSPKHVRFS---WHQDAVTVTCSDLSYGD- 145
Query 253 IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM-KEDGKG--- 308
L Y +QYR+ + W + T++ L Y F +R ED G
Sbjct 146 --LLYEVQYRSPFDTEWQ-----SKQENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDT 198
Query 309 YWSDWSEEASGITYE------DRPSKAPS 331
Y SDWSE E + P+
Sbjct 199 YPSDWSEVTCWQRGEIRDACAETPTPPKP 227
Score = 45.2 bits (105), Expect = 0.002, Method: Composition-based stats.
Identities = 47/295 (16%), Positives = 85/295 (29%), Gaps = 54/295 (18%)
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKA-PCITDWQQEDGTVHRTYLRGNLAESKCYLIT 495
+ V W + S + D+A T++ ++G L + Y +
Sbjct 40 ETVQVTWNASKYSRTNLTFHYRFNGDEAYDQCTNYLLQEGHTSGCLLDAEQRDDILY-FS 98
Query 496 VTPVYADGPGSPESIKAYLKQAP----PSKGPTVRTK----KVGKNEAVLEWDQLPVDVQ 547
+ + + PS VR V + L +
Sbjct 99 IRN-------GTHPVFTASRWMVYYLKPSSPKHVRFSWHQDAVTVTCSDLSY-------- 143
Query 548 NGFIRNYTIFYR-TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMA--AYTDEGGK--- 601
G + Y + YR + + T+ L ++ Y + A D G
Sbjct 144 -GDLL-YEVQYRSPFDTEWQSKQ--ENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDTY 199
Query 602 DGPEFTFT-------------TPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIK 648
T TP + ++ ++ LA LL L +L K +K
Sbjct 200 PSDWSEVTCWQRGEIRDACAETPTPPKPKLSKFILISSLAILLMVSLLLLS-LWKLWRVK 258
Query 649 KHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKP 703
K + P+VPDP P H N ++ + N + + + P
Sbjct 259 KFLIPSVPDPK-----SIFPGLFEIHQGNFQEWITDTQNVAHLHKMAGAEQESGP 308
>sp|Q9JIR0|RIMB1_RAT Peripheral-type benzodiazepine receptor-associated
protein 1 OS=Rattus norvegicus OX=10116 GN=Tspoap1
PE=1 SV=2
Length=1847
Score = 55.2 bits (131), Expect = 3e-06, Method: Composition-based stats.
Identities = 71/479 (15%), Positives = 123/479 (26%), Gaps = 87/479 (18%)
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLT 401
Q +V L W+ LPP + + V ++ A ++L ++
Sbjct 800 QLAHSVVLAWE-LPPERVDLRGFHIFVNGELRQALGPGVPPKAVLENMDLRAGPLHVSVQ 858
Query 402 VRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
G SD + P + W ++ +
Sbjct 859 ALTSKGSSDPLRCCLAMGAGAGVVPSQLRIHRLTATSAEITWVPGNSNLAHAVYLNGEEC 918
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP-VYADGPGSP----------ESI 510
A T W NL Y V + + GP P
Sbjct 919 PPARPSTYW----------ATFCNLRPGTLYQARVEAQIPSQGPWEPGWERPELRAATLQ 968
Query 511 KAYLKQAPPSKGPTVRTKK-VGKNEAVLEWDQLPVDVQ---NGF-IRNYTIF------YR 559
L P V+ + ++ W + +D NG + Y ++
Sbjct 969 FTTLPAGLPDAPLDVQAEPGPSPGIVMISWLPVTIDAAGTSNGVRVTGYAVYADGQKIME 1028
Query 560 TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE 619
+V V+ S + + V + + G E T + P
Sbjct 1029 VASPTAGSVLVEVSQLQLL------QACHEVTVRTMSPHG-----ESTDSIP-------- 1069
Query 620 AIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKS-HIAQWSPHTPPRHNFNS 678
PV A + C + R P V P S P RH
Sbjct 1070 ---APVAPALASACQPARMSCLSPRPS------PEVRTPLASVSPGLGYTSLPLRHPVPH 1120
Query 679 KDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLF-------KKEKINTEGHSSGIGGS 731
Q D + + + ++ P P + K+ T G +
Sbjct 1121 GTQ---DSPASLSTEMSKGPQEEPPVPCSQEEAGSAVHRTSEEKRAMEPTLGQEGPDPVA 1177
Query 732 SCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSE 790
++ +S D + +T + + PS +V R + LDSE
Sbjct 1178 PFLAKQAVECTSGDAGPTPCSTQEEL----------TQKEPSTEVCHRGD-----LDSE 1221
Score = 47.5 bits (111), Expect = 6e-04, Method: Composition-based stats.
Identities = 48/358 (13%), Positives = 97/358 (27%), Gaps = 49/358 (14%)
Query 112 EQNVYGITIISGLPPEK---------PKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKS 162
E+ G + PPE P++++ + + W+ E F +
Sbjct 766 EEEATGDELSLSPPPEGLGEPLAVPYPRHITVLKQLAHSVVLAWELPPERVDLRGFHIFV 825
Query 163 EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHI-NFDPVYKVK 221
+ P ++ + + V V+A + G +SD + +
Sbjct 826 NGELRQA----LGPGVPPKAVLENMDLRAGPLHVSVQALTSKG--SSDPLRCCLAMGAGA 879
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P L + ++ ++TW + L + + ++ +
Sbjct 880 GVVPSQLRIHRL--TATSAEITWVPGNSN----LAHAVYLNGEECPP--------ARPST 925
Query 282 SSFTVQDLKPFTEYVFRIRCM-KEDGKGYWSDWSEEASGITYE--DRPSKAPSFWYKIDP 338
T +L+P T Y R+ G E T + P+ P +
Sbjct 926 YWATFCNLRPGTLYQARVEAQIPSQGPWEPGWERPELRAATLQFTTLPAGLPDAPLDVQA 985
Query 339 SHTQGYRTVQLVWKTLPP---FEANG-KILDYEVTLTRWKSHLQNYTVNATKLT----VN 390
V + W + +NG ++ Y V K + L +
Sbjct 986 EPGPSPGIVMISWLPVTIDAAGTSNGVRVTGYAVYADGQKIMEVASPTAGSVLVEVSQLQ 1045
Query 391 LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE 448
L + T+ + G+S A A M + E
Sbjct 1046 LLQACHEVTVRTMSPHGES--------TDSIPAPVAPALASACQPARMSCLSPRPSPE 1095
>sp|Q26614|FGFR_STRPU Fibroblast growth factor receptor OS=Strongylocentrotus
purpuratus OX=7668 GN=FGFR PE=2 SV=1
Length=972
Score = 54.5 bits (129), Expect = 4e-06, Method: Composition-based stats.
Identities = 48/231 (21%), Positives = 77/231 (33%), Gaps = 10/231 (4%)
Query 377 LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-K 435
+ + T ++A L V S A TI + + P DL A P K
Sbjct 9 TRTVMFSRTLTRCYPQRTLWIAILCVICSWTLSTAGATTIRDKEVKPDAP-QDLTAIPVK 67
Query 436 DNMLWVEWTTP-RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLI 494
+ + W P + YI+ +C+ +K + E G V + NL + Y
Sbjct 68 AEAIVLTWKKPLKGQTDGYIVVYCLKRNKGNGCERQKIEGGNVTEVEV-TNLYANHTYQF 126
Query 495 TVTPVYADGPGSPESIKAYLK-QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN 553
V Y+D P + Y++ P PT+R G E L ++ R
Sbjct 127 QVQSWYSDHPKGAST--GYIEASGTPPIPPTLRRNFKGLVEKSLGFEHKIPCPVKADPRP 184
Query 554 YTIFYR---TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
YT + + + N+ NV + T L + A G
Sbjct 185 YTRWLKNGTDLTPNDPDDNVSFTKTSIVFKRLRFSDAGLYTCVASNFFGQP 235
Score = 51.0 bits (120), Expect = 5e-05, Method: Composition-based stats.
Identities = 39/228 (17%), Positives = 66/228 (29%), Gaps = 25/228 (11%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNP--SIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
VKP+ P +L+ I + + LTW P I+ Y ++ + +I +
Sbjct 53 VKPDAPQDLTAI--PVKAEAIVLTWKKPLKGQTDGYIVVYCLKRNKGNGCERQKIEGGNV 110
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
+ V +L Y F+++ D S EASG P P+
Sbjct 111 ----TEVEVTNLYANHTYQFQVQSWYSDHPKGASTGYIEASGT-----PPIPPTLRRNF- 160
Query 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLT-------VN 390
+G L ++ P Y L N + T
Sbjct 161 ----KGLVEKSLGFEHKIPCPVKADPRPYTRWLKNGTDLTPNDPDDNVSFTKTSIVFKRL 216
Query 391 LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNM 438
+D L T N G+ T+ D + ++
Sbjct 217 RFSDAGLYTCVASNFFGQPIHVNFTLIVVDTHSESYAESSVLESFSSL 264
Score = 46.8 bits (109), Expect = 0.001, Method: Composition-based stats.
Identities = 19/105 (18%), Positives = 36/105 (34%), Gaps = 3/105 (3%)
Query 515 KQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSH 574
K+ P + V VL W + +G+I Y + G E +
Sbjct 51 KEVKPDAPQDLTAIPVKAEAIVLTWKKPLKGQTDGYIVVYCLKRNKGNGCERQKIEGGNV 110
Query 575 TEYTLSSLTSDTLYMVRMAAYTDE---GGKDGPEFTFTTPKFAQG 616
TE +++L ++ Y ++ ++ + G G TP
Sbjct 111 TEVEVTNLYANHTYQFQVQSWYSDHPKGASTGYIEASGTPPIPPT 155
Score = 36.4 bits (82), Expect = 1.6, Method: Composition-based stats.
Identities = 12/102 (12%), Positives = 33/102 (32%), Gaps = 2/102 (2%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD 185
P+ P++L+ I + + + W + + + + K + V+
Sbjct 55 PDAPQDLTAIPVKAEAIVLTWKKPLKGQTDGYIVVYCLKRNKGNGCERQKIEGGNVTEVE 114
Query 186 YSTVY-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPH 226
+ +Y + V++ + + + P PP
Sbjct 115 VTNLYANHTYQFQVQSWYSDHPKGASTGYIEA-SGTPPIPPT 155
>sp|Q968Y9|INSR_CAEEL Insulin-like receptor OS=Caenorhabditis
elegans OX=6239 GN=daf-2 PE=1 SV=2
Length=1846
Score = 54.9 bits (130), Expect = 4e-06, Method: Composition-based stats.
Identities = 37/196 (19%), Positives = 60/196 (31%), Gaps = 25/196 (13%)
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR-CMK 303
++ I Y I Y S + +S+ +++LK +T Y + C
Sbjct 992 KPTTVPGTRIRLYEI-YEPLPGSWAINVSALALD---NSYVIRNLKHYTLYAISLSACQN 1047
Query 304 EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH----TQGYRTVQLVWKTLPPFEA 359
G S A + R ++ + + V + W PP E
Sbjct 1048 MTVPGASCSISHRAGAL---KRTKHITDIDKVLNETIEWRFMNNSQQVNVTWD--PPTEV 1102
Query 360 NGKILDYEVTL-----------TRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGK 408
NG I Y V L + T N L NL + RY ++T ++ G
Sbjct 1103 NGGIFGYVVKLKSKVDGSIVMTRCVGAKRGYSTRNQGVLFQNLADGRYFVSVTATSVHGA 1162
Query 409 SDAAVLTIPACDFQAT 424
A + P
Sbjct 1163 GPEAESSDPIVVMTPG 1178
Score = 53.7 bits (127), Expect = 8e-06, Method: Composition-based stats.
Identities = 35/223 (16%), Positives = 68/223 (30%), Gaps = 30/223 (13%)
Query 447 RESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPV-YADGPG 505
+V + + + P + +Y+ NL Y I+++ PG
Sbjct 993 PTTVPGTRIRLYEIYEPLPGSWAINVSALALDNSYVIRNLKHYTLYAISLSACQNMTVPG 1052
Query 506 SPESIK------AYLKQAPPSKGPTVRTKKVG------KNEAVLEWDQLPVDVQNGFIRN 553
+ SI K + V + + + + WD P NG I
Sbjct 1053 ASCSISHRAGALKRTKHI--TDIDKVLNETIEWRFMNNSQQVNVTWD--PPTEVNGGIFG 1108
Query 554 YTIFYRTIIGNETAVN--------VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
Y + ++ + + + + +L +D Y V + A + G E
Sbjct 1109 YVVKLKSKVDGSIVMTRCVGAKRGYSTRNQGVLFQNL-ADGRYFVSVTATSVHGAGPEAE 1167
Query 606 FT----FTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKR 644
+ TP F EI ++ V L + + + R
Sbjct 1168 SSDPIVVMTPGFFTVEIILGMLLVFLILMSIAGCIIYYYIQVR 1210
Score = 49.5 bits (116), Expect = 2e-04, Method: Composition-based stats.
Identities = 34/230 (15%), Positives = 77/230 (33%), Gaps = 26/230 (11%)
Query 63 NYIVWKTNHFTIPKEQYTIINRTAS-------SVTFTDIASLNIQLTCNILTFGQLEQNV 115
++ K N P +Q N + +V+ T + + ++ + ++Q
Sbjct 620 KQLMSKLNIPLDPIDQSEGTNGEKAICEDMAINVSITAVNADSVFFSWPSFNITDIDQRK 679
Query 116 Y-GITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA 174
+ G + P +N++ I + W + + ET+ D
Sbjct 680 FLGYELFFKEVPRIDENMT-IEEDRSACVDSWQSVFKQYYETS-------NGEPTPDIFM 731
Query 175 KRDTPTSCTVDYSTVYF--VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
+ Y+ + + A+N + K I F P+PP ++
Sbjct 732 DIGPRERIRPNTLYAYYVATQMVLHAGAKNGVSK-----IGFVRTSYYTPDPP---TLAL 783
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
++ S + +TW P + + Y I +R + S + + T ++
Sbjct 784 AQVDSDAIHITWEAPLQPNGDLTHYTIMWRENEVSPYEEAEKFCTDASTP 833
Score = 49.1 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 19/114 (17%), Positives = 35/114 (31%), Gaps = 12/114 (11%)
Query 458 CVLSDKAPCITDWQQEDGTVHRTYL-----RGNLAESKCYLITVTPV----YADGPGSPE 508
CV S ++ ++ +G R + + Y V G +
Sbjct 706 CVDSWQSVFKQYYETSNGEPTPDIFMDIGPRERIRPNTLYAYYVATQMVLHAGAKNGVSK 765
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII 562
P PT+ +V + + W+ NG + +YTI +R
Sbjct 766 IGFVRTSYYTPD-PPTLALAQVDSDAIHITWEA--PLQPNGDLTHYTIMWRENE 816
Score = 43.3 bits (100), Expect = 0.012, Method: Composition-based stats.
Identities = 19/91 (21%), Positives = 36/91 (40%), Gaps = 5/91 (5%)
Query 236 LSSILKLTWTNPSIKSVIILKYNIQYRTK-DASTWSQ--IPPEDTASTRSS-FTVQDLKP 291
S + +TW P+ + I Y ++ ++K D S + + STR+ Q+L
Sbjct 1088 NSQQVNVTWDPPTEVNGGIFGYVVKLKSKVDGSIVMTRCVGAKRGYSTRNQGVLFQNL-A 1146
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
Y + G G ++ S+ +T
Sbjct 1147 DGRYFVSVTATSVHGAGPEAESSDPIVVMTP 1177
>sp|Q924V5|IL12B_CAVPO Interleukin-12 subunit beta OS=Cavia porcellus
OX=10141 GN=IL12B PE=2 SV=1
Length=332
Score = 53.3 bits (126), Expect = 5e-06, Method: Composition-based stats.
Identities = 34/202 (17%), Positives = 66/202 (33%), Gaps = 30/202 (15%)
Query 132 LSCIVNEGKK-MRCEW---------------DGGRETHLETNFTLKSEWATHKFADCKAK 175
L C C W G + T + ++ +
Sbjct 129 LKCEARSYSGRFTCWWLTAFGTDVKFSVKGSRGSSDPSGVTCGEAERVSGDNQEYKYSVE 188
Query 176 RDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEE 235
++C ++ IEV V+A + K + +F +KP+PP NL + S
Sbjct 189 CQEDSACPTAEESL---PIEVVVDAIHKF-KYENYTSSFYIRDIIKPDPPKNLQLKPS-V 243
Query 236 LSSILKLTWTNP----SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKP 291
S ++++W P + S L + +Q K+ + + T T ++ + +
Sbjct 244 NSQQVEVSWEYPDTWSTPHSYFSLTFLVQTHGKNKNRREKKYELFTDKTSATVSCHKIS- 302
Query 292 FTEYVFRIRCMKEDGKGYWSDW 313
+R WS+W
Sbjct 303 ----KVEVRARDRYYSSSWSEW 320
>sp|P48095|IL12B_MACMU Interleukin-12 subunit beta OS=Macaca mulatta
OX=9544 GN=IL12B PE=2 SV=1
Length=328
Score = 53.3 bits (126), Expect = 5e-06, Method: Composition-based stats.
Identities = 42/226 (19%), Positives = 74/226 (33%), Gaps = 35/226 (15%)
Query 112 EQNVYGITIISGLPPEKPKN---LSCIV-NEGKKMRCEWDGGRETHLETNFTLKSEWATH 167
E ++ ++ ++PKN L C N + C W T L + +
Sbjct 108 EDGIWSTDVLKDQ--KEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSNP 165
Query 168 KFADC-------------KAKRDTPTSCTVDYS---TVYFVNIEVWVEAENALGKVTSDH 211
+ C + + C D + + IEV V+A + L K +
Sbjct 166 QGVTCGAVTLSAERVRGDNKEYEYSVECQEDSACPAAEERLPIEVMVDAIHKL-KYENYT 224
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP----SIKSVIILKYNIQYRTKDAS 267
+F +KP+PP NL + + S ++++W P + S L + IQ + K
Sbjct 225 SSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWSTPHSYFSLTFCIQVQGKSKR 283
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
D S F ++ WS+W
Sbjct 284 EKKDRIFTDKTSATVICR-------KNASFSVQAQDRYYSSSWSEW 322
>sp|Q696W0|SPEG_DANRE Striated muscle preferentially expressed
protein kinase OS=Danio rerio OX=7955 GN=speg PE=2 SV=1
Length=2995
Score = 54.5 bits (129), Expect = 5e-06, Method: Composition-based stats.
Identities = 33/155 (21%), Positives = 53/155 (34%), Gaps = 10/155 (6%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII----L 255
N +GK + V P PP VI ++ L+W P I L
Sbjct 914 ISNKVGKAACYAHLYVAVSL--PEPPDGPPVI-ESVTGRMILLSWKKPKNLDPSIDPASL 970
Query 256 KYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE 315
Y +Q + ++ W+ I T +S+TV L Y FR+ S ++
Sbjct 971 MYVVQQQVLGSTQWTTIASSLTD---TSYTVTSLSKGVCYSFRVLSTTGKTLSKPSQPTD 1027
Query 316 EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
+ + KAP K D + + V +
Sbjct 1028 LVQLVDRGEYFRKAPVIIDKPDIVYAVENQPVTIT 1062
Score = 45.6 bits (106), Expect = 0.003, Method: Composition-based stats.
Identities = 28/141 (20%), Positives = 49/141 (35%), Gaps = 11/141 (8%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A N L VT+ I P P + ++ + + W + + Y I
Sbjct 2399 ATNNLASVTTSCILTLACIPNCPGTPEIRQI-----YNNTVLVQWKP--SDTKVPCTYTI 2451
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ + W E T T F +L + FR+ C+ + G+ +S+ S+ S
Sbjct 2452 EKKFDGDDKW---LTEATGVTDCFFNSSELPSGSTIRFRVACVNKAGQSPYSNESDGVSI 2508
Query 320 ITYEDRPSKAPSFWYKIDPSH 340
T P P+ P+
Sbjct 2509 DTK-VTPQHQPAKMKTHSPAS 2528
Score = 43.7 bits (101), Expect = 0.012, Method: Composition-based stats.
Identities = 26/179 (15%), Positives = 52/179 (29%), Gaps = 23/179 (13%)
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLA 398
G ++ W NGK ++ T + Q V++ + + +
Sbjct 861 CRVTGLPYPKITW------YHNGK----KIESTNDRKMTQYRDVHSLVIQSVCHDHSGVY 910
Query 399 TLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE-------SVK 451
+ N VGK+ A + M+ + W P+ +
Sbjct 911 KCVISNKVGKAACYAHLYVAVSLPEPPDGPPVIESVTGRMILLSWKKPKNLDPSIDPASL 970
Query 452 KYILEWCVLSDKAPCITDWQQEDGTVHRT-YLRGNLAESKCYLITVTPVYADGPGSPES 509
Y+++ + T W ++ T Y +L++ CY V P
Sbjct 971 MYVVQ-----QQVLGSTQWTTIASSLTDTSYTVTSLSKGVCYSFRVLSTTGKTLSKPSQ 1024
Score = 39.8 bits (91), Expect = 0.14, Method: Composition-based stats.
Identities = 17/84 (20%), Positives = 32/84 (38%), Gaps = 9/84 (11%)
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQL----PVDVQNGFIRNYTIFYRTIIG-NETAVNVDS 572
PP P + + V +L W + P + Y + + + T +
Sbjct 936 PPDGPPVI--ESVTGRMILLSWKKPKNLDPSIDPASLM--YVVQQQVLGSTQWTTIASSL 991
Query 573 SHTEYTLSSLTSDTLYMVRMAAYT 596
+ T YT++SL+ Y R+ + T
Sbjct 992 TDTSYTVTSLSKGVCYSFRVLSTT 1015
>sp|P46658|IL12B_CERAT Interleukin-12 subunit beta OS=Cercocebus
atys OX=9531 GN=IL12B PE=2 SV=1
Length=328
Score = 53.3 bits (126), Expect = 5e-06, Method: Composition-based stats.
Identities = 46/247 (19%), Positives = 82/247 (33%), Gaps = 44/247 (18%)
Query 100 QLTCN---------ILTFGQLEQNVYGITIISGLPPEKPKN---LSCIV-NEGKKMRCEW 146
Q TC+ +L + E ++ I+ ++PKN L C N ++ C W
Sbjct 87 QYTCHKGGEALSHSLLLPHKKEDGIWSTDILKDQ--KEPKNETFLRCEAKNYSGRITCWW 144
Query 147 DGGRETHLETNFTLKSEWATHKFADC-------------KAKRDTPTSCTVDYS---TVY 190
T L + + + C + + C D +
Sbjct 145 LSTISTDLTFSIISSRGSSNPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAAEE 204
Query 191 FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP--- 247
+ IEV V+A + L K + +F +KP+PP NL + + S ++++W P
Sbjct 205 RLPIEVMVDAIHKL-KYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTW 262
Query 248 -SIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ S L + IQ + K D S F ++
Sbjct 263 STPHSYFSLTFCIQVQGKSKREKKDRIFTDKTSATVICR-------KNASFSVQAQDRYY 315
Query 307 KGYWSDW 313
W++W
Sbjct 316 SSSWNEW 322
>sp|Q15772|SPEG_HUMAN Striated muscle preferentially expressed
protein kinase OS=Homo sapiens OX=9606 GN=SPEG PE=1 SV=4
Length=3267
Score = 54.5 bits (129), Expect = 6e-06, Method: Composition-based stats.
Identities = 32/147 (22%), Positives = 48/147 (33%), Gaps = 11/147 (7%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNI 259
A N LG +TS K PP + W S Y +
Sbjct 2659 ATNVLGSITSSCTVAVARVPGKLAPPEVPQ-----TYQDTALVLWKPGD--SRAPCTYTL 2711
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ R S W P + + V L FR+ C G+G +S+ SE+
Sbjct 2712 ERRVDGESVWH---PVSSGIPDCYYNVTHLPVGVTVRFRVACANRAGQGPFSNSSEKVFV 2768
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRT 346
+D S PS ++ P ++ R
Sbjct 2769 RGTQDS-SAVPSAAHQEAPVTSRPARA 2794
Score = 50.2 bits (118), Expect = 1e-04, Method: Composition-based stats.
Identities = 35/174 (20%), Positives = 63/174 (36%), Gaps = 25/174 (14%)
Query 200 AENALGKVTS-DHINFDPVYKVKPN-PPHNLSVINSEELSSILKLTWTNPSIKSVII--- 254
N LGK H+ V P+ P ++V ++ LTW P + I
Sbjct 1262 IANKLGKAACYAHLYVTDVVPGPPDGAPQVVAV-----TGRMVTLTWNPPRSLDMAIDPD 1316
Query 255 -LKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
L Y +Q++ + W+ + T + L+ +++FR+ S
Sbjct 1317 SLTYTVQHQVLGSDQWTAL---VTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPP 1373
Query 314 SEEA----SGITYEDRPS--KAPSFWYKID-----PSHTQGYRTVQLVWKTLPP 356
SE G T E+ P+ P Y ++ + T + Q+VW++
Sbjct 1374 SEPVQLLEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNHVEAQVVWRSCRG 1427
>sp|Q01113|IL9R_HUMAN Interleukin-9 receptor OS=Homo sapiens OX=9606
GN=IL9R PE=1 SV=3
Length=521
Score = 53.7 bits (127), Expect = 6e-06, Method: Composition-based stats.
Identities = 39/222 (18%), Positives = 70/222 (32%), Gaps = 24/222 (11%)
Query 132 LSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYF 191
+C+ N ++ C W + + L + R + + + V
Sbjct 54 FTCLTNNILRIDCHWSAPELGQGSSPWLLFTSNQAPGGTHKCILRGSECTVVLPPEAVLV 113
Query 192 VNIEVWVEAENALGKVTSDHINFDPVYK----VKPNPPHNLSVINSEELSSILKLTWT-- 245
+ + + + DP Y VK +PP +L S S LTW+
Sbjct 114 PSDNFTITFHHCM-SGREQVSLVDPEYLPRRHVKLDPPSDLQ---SNISSGHCILTWSIS 169
Query 246 NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV--QDLKPFTEYVFRIRCM- 302
+L Y + ++ K W Q D + + +L P + R+R
Sbjct 170 PALEPMTTLLSYELAFK-KQEEAWEQAQHRDHIVGVTWLILEAFELDPGFIHEARLRVQM 228
Query 303 ---------KEDGKGYWSDWSEEASGITYEDR-PSKAPSFWY 334
+E G WS+WS+ + + P P W
Sbjct 229 ATLEDDVVEEERYTGQWSEWSQPVCFQAPQRQGPLIPPWGWP 270
>sp|Q6PCB0|VWA1_HUMAN von Willebrand factor A domain-containing
protein 1 OS=Homo sapiens OX=9606 GN=VWA1 PE=1 SV=1
Length=445
Score = 53.7 bits (127), Expect = 6e-06, Method: Composition-based stats.
Identities = 32/216 (15%), Positives = 55/216 (25%), Gaps = 34/216 (16%)
Query 413 VLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTP-RESVKKYILEWCVLSDKAPCITDWQ 471
V + A P + + W Y+LE ++ P Q
Sbjct 202 VQELRGSILDAMRPQQLHATEITSSGFRLAWPPLLTADSGYYVLE--LVPSAQPGAARRQ 259
Query 472 QEDGTVHRTYLRGNLAESKCY----------------LITVTPVYAD----------GPG 505
Q G ++ L Y ++ V + G G
Sbjct 260 QLPGNATD-WIWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAG 318
Query 506 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE 565
+ A L + + + W + + Y + + + G E
Sbjct 319 PAPTQLAALPAPEEAGPERIVISHARPRSLRVSWA---PALGSAAALGYHVQFGPLRGGE 375
Query 566 -TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG 600
V V + TL L T Y+V + A G
Sbjct 376 AQRVEVPAGRNCTTLQGLAPGTAYLVTVTAAFRSGR 411
Score = 46.0 bits (107), Expect = 0.001, Method: Composition-based stats.
Identities = 19/107 (18%), Positives = 40/107 (37%), Gaps = 9/107 (8%)
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQ 260
E+ G + + P ++ S L+++W P++ S L Y++Q
Sbjct 314 ESGAGPAPTQLAALPAPEEAGPE-----RIVISHARPRSLRVSWA-PALGSAAALGYHVQ 367
Query 261 YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGK 307
+ ++ + R+ T+Q L P T Y+ + G+
Sbjct 368 FGPLRGGEAQRVE---VPAGRNCTTLQGLAPGTAYLVTVTAAFRSGR 411
Score = 43.7 bits (101), Expect = 0.008, Method: Composition-based stats.
Identities = 35/209 (17%), Positives = 56/209 (27%), Gaps = 31/209 (15%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P L +E SS +L W P + + Y ++ ++ + + +
Sbjct 215 PQQLHA--TEITSSGFRLAW--PPLLTADSGYYVLELVP--SAQPGAARRQQLPGNATDW 268
Query 285 TVQDLKPFTEYVF----------------RIRCMK-EDGKGYWSDWSEEASGITYEDRPS 327
L P T+Y R+R E G G S T
Sbjct 269 IWAGLDPDTDYDVALVPESNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPTQLAALP 328
Query 328 KAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQN-----YTV 382
+ R++++ W A L Y V +
Sbjct 329 APEEAGPERIVISHARPRSLRVSWAPALGSAAA---LGYHVQFGPLRGGEAQRVEVPAGR 385
Query 383 NATKLTVNLTNDRYLATLTVRNLVGKSDA 411
N T L YL T+T G+ A
Sbjct 386 NCTTLQGLAPGTAYLVTVTAAFRSGRESA 414
Score = 39.8 bits (91), Expect = 0.11, Method: Composition-based stats.
Identities = 39/223 (17%), Positives = 63/223 (28%), Gaps = 24/223 (11%)
Query 298 RIRCMKEDGKGYWSDWSEEASGIT----YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
++ + G+ W + + E PS P + +W
Sbjct 217 QLHATEITSSGFRLAWPPLLTADSGYYVLELVPSAQPGAARRQQLPGNATDW----IWAG 272
Query 354 LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAV 413
L P DY+V L N + ++ T G A
Sbjct 273 LDPD------TDYDVALVPE----SNVRLLRPQILRVRTRPGEAGPGASGPESGAGPAPT 322
Query 414 LTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESV--KKYILEWCVLSDKAPCITDWQ 471
+ P + + + L V W S Y +++ L
Sbjct 323 QLAALPAPEEAGPERIVISHARPRSLRVSWAPALGSAAALGYHVQFGPLRGGEAQRV--- 379
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYL 514
+ + T L+G LA YL+TVT + G S S KA
Sbjct 380 EVPAGRNCTTLQG-LAPGTAYLVTVTAAFRSGRESALSAKACT 421
>sp|Q9Z2L7|CRLF3_MOUSE Cytokine receptor-like factor 3 OS=Mus
musculus OX=10090 GN=Crlf3 PE=1 SV=1
Length=442
Score = 53.3 bits (126), Expect = 6e-06, Method: Composition-based stats.
Identities = 23/104 (22%), Positives = 41/104 (39%), Gaps = 8/104 (8%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
V PP + + E + + W Y +Q+R A+ + +
Sbjct 176 TVASRPP--VQIEELIEKPGGIIVRWCK-VDDDFTAQDYRLQFRKCTANHFEDVY----V 228
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ + F V + P +Y FR+ C + DG+ WS WS +G +
Sbjct 229 GSETEFIVLHIDPNVDYQFRV-CARGDGRQEWSPWSVPQTGHST 271
Score = 43.7 bits (101), Expect = 0.006, Method: Composition-based stats.
Identities = 17/98 (17%), Positives = 36/98 (37%), Gaps = 5/98 (5%)
Query 515 KQAPPSKGPTVRTKKV--GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS 572
K + P V+ +++ ++ W ++ D ++Y + +R N
Sbjct 173 KHGTVASRPPVQIEELIEKPGGIIVRWCKVDDDF---TAQDYRLQFRKCTANHFEDVYVG 229
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
S TE+ + + + Y R+ A D + P T
Sbjct 230 SETEFIVLHIDPNVDYQFRVCARGDGRQEWSPWSVPQT 267
>sp|P29460|IL12B_HUMAN Interleukin-12 subunit beta OS=Homo sapiens
OX=9606 GN=IL12B PE=1 SV=1
Length=328
Score = 52.9 bits (125), Expect = 7e-06, Method: Composition-based stats.
Identities = 41/223 (18%), Positives = 78/223 (35%), Gaps = 29/223 (13%)
Query 112 EQNVYGITIISGLPPEKPKN---LSCIV-NEGKKMRCEW---------------DGGRET 152
E ++ I+ ++PKN L C N + C W G +
Sbjct 108 EDGIWSTDILKDQ--KEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDP 165
Query 153 HLET--NFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSD 210
T TL +E + + + + IEV V+A + L K +
Sbjct 166 QGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAAEESLP-IEVMVDAVHKL-KYENY 223
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS 270
+F +KP+PP NL + + S ++++W P S +++ + +
Sbjct 224 TSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSK 282
Query 271 QIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
+ + + ++S TV K + +R WS+W
Sbjct 283 REKKDRVFTDKTSATVICRKNAS---ISVRAQDRYYSSSWSEW 322
>sp|Q1L867|FNDC5_DANRE Fibronectin type III domain-containing
protein 5 OS=Danio rerio OX=7955 GN=fndc5 PE=3 SV=1
Length=207
Score = 51.4 bits (121), Expect = 8e-06, Method: Composition-based stats.
Identities = 35/190 (18%), Positives = 68/190 (36%), Gaps = 24/190 (13%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P N+++ E S+I+ TW ++ ++ + I + KD I +T T S
Sbjct 31 APLNVTIKALEGNSAIV--TWD--ILEGDPVIGFAITQQKKDVRMLRFIQEVNT--TTRS 84
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY---EDRPSKAPSFWYKIDPSH 340
+ DL+ TEY+ ++ + G S SE T E SK+P +
Sbjct 85 CALWDLEEDTEYIVHVQSISMSGT---SPPSEPVLFRTPKESEKLASKSPDEVTMEEVGQ 141
Query 341 TQGYRT--------VQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLT 392
R V ++W + Y++ ++ ++ N+++ +
Sbjct 142 AAQLRAGELIIIVVVLVMWAGVIALF----CRQYDIIKDNEPNNNKDKAKNSSECSTPEH 197
Query 393 NDRYLATLTV 402
L V
Sbjct 198 PTGGLLRSKV 207
>sp|Q6ZTA4|TRI67_HUMAN Tripartite motif-containing protein 67
OS=Homo sapiens OX=9606 GN=TRIM67 PE=1 SV=3
Length=783
Score = 53.7 bits (127), Expect = 8e-06, Method: Composition-based stats.
Identities = 15/99 (15%), Positives = 32/99 (32%), Gaps = 6/99 (6%)
Query 214 FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIP 273
+V P P L + ++ + L W P + Y ++ + ++
Sbjct 506 IQMKCRVPPVP--LLQLEKCCTRNNSVTLAWRMPPFTHSPVDGYILELDDGAGGQFREVY 563
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ T+ L + Y R++ G G +S
Sbjct 564 ----VGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSK 598
Score = 49.1 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 15/85 (18%), Positives = 24/85 (28%), Gaps = 2/85 (2%)
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEY 577
PP + N L W P + Y + G + T
Sbjct 513 PPVPLLQLEKCCTRNNSVTLAWRMPPFTH--SPVDGYILELDDGAGGQFREVYVGKETLC 570
Query 578 TLSSLTSDTLYMVRMAAYTDEGGKD 602
T+ L ++ Y R+ A+ G
Sbjct 571 TIDGLHFNSTYNARVKAFNSSGVGP 595
Score = 40.6 bits (93), Expect = 0.076, Method: Composition-based stats.
Identities = 15/97 (15%), Positives = 25/97 (26%), Gaps = 8/97 (8%)
Query 419 CDFQATHPVMDLKAFPKDNMLWVEWTTPR---ESVKKYILEWCVLSDKAPCITDWQQEDG 475
C + K ++N + + W P V YILE +++
Sbjct 510 CRVPPVPLLQLEKCCTRNNSVTLAWRMPPFTHSPVDGYILE-----LDDGAGGQFREVYV 564
Query 476 TVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
L + Y V + G G
Sbjct 565 GKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTVV 601
>sp|P82458|TRI18_RAT E3 ubiquitin-protein ligase Midline-1 OS=Rattus
norvegicus OX=10116 GN=Mid1 PE=2 SV=1
Length=667
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 22/117 (19%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT-----------K 264
Y PNPP + + + + + WT S ++ Y +QY
Sbjct 376 LDYLTAPNPPTIREELCTASYDT-ITVHWT--SDDEFSVVSYELQYTIFTGQANVVSLCN 432
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
A +W +P ++ +TV L+ T+Y+F ++ + + G S SE T
Sbjct 433 SADSWMIVP----NIKQNHYTVHGLQSGTKYIFMVKAINQAG----SRSSEPGKLKT 481
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 25/134 (19%), Positives = 42/134 (31%), Gaps = 9/134 (7%)
Query 409 SDAAVLTIPACDFQATHPVMDLKA--FPKDNMLWVEWTTPRE-SVKKYILEWCVLSDKAP 465
S L A +P + + + V WT+ E SV Y L++ + + +A
Sbjct 367 SREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQAN 426
Query 466 CIT------DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
++ W Y L Y+ V + G S E K P
Sbjct 427 VVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLKTNSQPF 486
Query 520 SKGPTVRTKKVGKN 533
P +K+ +
Sbjct 487 KLDPKSAHRKLKVS 500
Score = 41.8 bits (96), Expect = 0.030, Method: Composition-based stats.
Identities = 17/96 (18%), Positives = 29/96 (30%), Gaps = 10/96 (10%)
Query 517 APPSKGPTVR--TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI-------IGNETA 567
P+ PT+R + + W + YTIF +
Sbjct 380 TAPN-PPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWM 438
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ + YT+ L S T Y+ + A G +
Sbjct 439 IVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSS 474
>sp|P82457|TRI18_MUSSP E3 ubiquitin-protein ligase Midline-1 OS=Mus
spretus OX=10096 GN=Mid1 PE=2 SV=1
Length=667
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 22/117 (19%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT-----------K 264
Y PNPP + + + + + WT S ++ Y +QY
Sbjct 376 LDYLTAPNPPTIREELCTASYDT-ITVHWT--SDDEFSVVSYELQYTIFTGQANVVSLCN 432
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
A +W +P ++ +TV L+ T+Y+F ++ + + G S SE T
Sbjct 433 SADSWMIVP----NIKQNHYTVHGLQSGTKYIFMVKAINQAG----SRSSEPGKLKT 481
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 25/134 (19%), Positives = 42/134 (31%), Gaps = 9/134 (7%)
Query 409 SDAAVLTIPACDFQATHPVMDLKA--FPKDNMLWVEWTTPRE-SVKKYILEWCVLSDKAP 465
S L A +P + + + V WT+ E SV Y L++ + + +A
Sbjct 367 SREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQAN 426
Query 466 CIT------DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
++ W Y L Y+ V + G S E K P
Sbjct 427 VVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLKTNSQPF 486
Query 520 SKGPTVRTKKVGKN 533
P +K+ +
Sbjct 487 KLDPKSAHRKLKVS 500
Score = 41.8 bits (96), Expect = 0.030, Method: Composition-based stats.
Identities = 17/96 (18%), Positives = 29/96 (30%), Gaps = 10/96 (10%)
Query 517 APPSKGPTVR--TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI-------IGNETA 567
P+ PT+R + + W + YTIF +
Sbjct 380 TAPN-PPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWM 438
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ + YT+ L S T Y+ + A G +
Sbjct 439 IVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSS 474
>sp|O15344|TRI18_HUMAN E3 ubiquitin-protein ligase Midline-1 OS=Homo
sapiens OX=9606 GN=MID1 PE=1 SV=1
Length=667
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 22/117 (19%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT-----------K 264
Y PNPP + + + + + WT S ++ Y +QY
Sbjct 376 LDYLTAPNPPTIREELCTASYDT-ITVHWT--SDDEFSVVSYELQYTIFTGQANVVSLCN 432
Query 265 DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
A +W +P ++ +TV L+ T+Y+F ++ + + G S SE T
Sbjct 433 SADSWMIVP----NIKQNHYTVHGLQSGTKYIFMVKAINQAG----SRSSEPGKLKT 481
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 25/134 (19%), Positives = 42/134 (31%), Gaps = 9/134 (7%)
Query 409 SDAAVLTIPACDFQATHPVMDLKA--FPKDNMLWVEWTTPRE-SVKKYILEWCVLSDKAP 465
S L A +P + + + V WT+ E SV Y L++ + + +A
Sbjct 367 SREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQAN 426
Query 466 CIT------DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
++ W Y L Y+ V + G S E K P
Sbjct 427 VVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLKTNSQPF 486
Query 520 SKGPTVRTKKVGKN 533
P +K+ +
Sbjct 487 KLDPKSAHRKLKVS 500
Score = 41.8 bits (96), Expect = 0.030, Method: Composition-based stats.
Identities = 17/96 (18%), Positives = 29/96 (30%), Gaps = 10/96 (10%)
Query 517 APPSKGPTVR--TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI-------IGNETA 567
P+ PT+R + + W + YTIF +
Sbjct 380 TAPN-PPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWM 438
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ + YT+ L S T Y+ + A G +
Sbjct 439 IVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSS 474
>sp|Q8BYN5|FSD1L_MOUSE FSD1-like protein OS=Mus musculus OX=10090
GN=Fsd1l PE=1 SV=2
Length=507
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 38/231 (16%), Positives = 69/231 (30%), Gaps = 45/231 (19%)
Query 225 PHNLSVINSE--ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT----- 277
P + E + + + W P + I + ++YR + ++ E
Sbjct 165 PKAPEIDPVECLVADNSVTVAWRMPEEDN-KIDHFIMEYRKTNFDGLPRVKDERCWEVID 223
Query 278 ASTRSSFTVQDLKPFTEYV-FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ +T+ LK ++Y+ FR+R + G +SD +T E R +
Sbjct 224 NIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGDYSDP------VTLETR---------AL 268
Query 337 DPSHTQGYRTVQLV-------WKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV 389
+ S + L W KI K +V+ T L
Sbjct 269 NFSLDNSSSHLNLKVEDSCVEWDPTGGKGQESKI----------KGKENKGSVHVTSLKK 318
Query 390 NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLW 440
+ + R VG AV ++ V+ A W
Sbjct 319 HTSGTPSPK----RTSVGSRPPAVRGSRDRFTGESYTVLGDTAIENGQHYW 365
>sp|Q505D9|TRI67_MOUSE Tripartite motif-containing protein 67
OS=Mus musculus OX=10090 GN=Trim67 PE=2 SV=1
Length=768
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 19/131 (15%), Positives = 35/131 (27%), Gaps = 2/131 (2%)
Query 472 QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG 531
+ T +++G L +T + + + PP +
Sbjct 452 KRVQTSQEQWVKGALEPKVSAEFDLTLDSEPLLQAIHQLDFVQMKLPPVPLLQLEKCCTR 511
Query 532 KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
N L W P Y + G + T T+ L ++ Y R
Sbjct 512 NNSVTLAWRTPPFTH--SPAEGYILELDDGDGGQFREVYVGKETLCTIDGLHFNSTYNAR 569
Query 592 MAAYTDEGGKD 602
+ A+ G
Sbjct 570 VKAFNSSGVGP 580
Score = 51.4 bits (121), Expect = 4e-05, Method: Composition-based stats.
Identities = 15/91 (16%), Positives = 30/91 (33%), Gaps = 5/91 (5%)
Query 223 NPPHNL-SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
PP L + ++ + L W P Y ++ D + ++
Sbjct 497 LPPVPLLQLEKCCTRNNSVTLAWRTPPFTHSPAEGYILELDDGDGGQFREVY----VGKE 552
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ T+ L + Y R++ G G +S
Sbjct 553 TLCTIDGLHFNSTYNARVKAFNSSGVGPYSK 583
Score = 40.2 bits (92), Expect = 0.11, Method: Composition-based stats.
Identities = 14/95 (15%), Positives = 25/95 (26%), Gaps = 8/95 (8%)
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPR---ESVKKYILEWCVLSDKAPCITDWQQEDGTV 477
+ K ++N + + W TP + YILE +++
Sbjct 497 LPPVPLLQLEKCCTRNNSVTLAWRTPPFTHSPAEGYILE-----LDDGDGGQFREVYVGK 551
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKA 512
L + Y V + G G
Sbjct 552 ETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTVV 586
>sp|Q7TNF8|RIMB1_MOUSE Peripheral-type benzodiazepine receptor-associated
protein 1 OS=Mus musculus OX=10090 GN=Tspoap1 PE=2
SV=2
Length=1846
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 68/453 (15%), Positives = 117/453 (26%), Gaps = 82/453 (18%)
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLT 401
Q +V L W+ LPP + + V ++ A ++L ++
Sbjct 798 QLAHSVVLAWE-LPPERVDLRGFHIFVNGELRQALGPGVPPKAVLENMDLRTGPLHVSVQ 856
Query 402 VRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLS 461
G SD + P + W ++ I
Sbjct 857 ALTSKGSSDPLRCCLAVGAGAGVVPSQLRIHRLTATSAEIAWVPGNSNLAHAIYLNGEEC 916
Query 462 DKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP-VYADGPGSP----------ESI 510
A T W NL Y V + + GP P
Sbjct 917 PPARPSTYW----------ATFCNLRPGTLYQARVEAQIPSQGPWEPGWERPEQRAATLQ 966
Query 511 KAYLKQAPPSKGPTVRTKK-VGKNEAVLEWDQLPVDVQ---NGF-IRNYTIF------YR 559
L P V+ + ++ W + +D NG + Y I+
Sbjct 967 FTTLPAGLPDAPLDVQAEPGPSPGILMISWLPVTIDAAGTSNGVRVTGYAIYADGQKIME 1026
Query 560 TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE 619
+V V+ S + + V + + G E + + P
Sbjct 1027 VASPTAGSVLVEVSQLQLL------QACHEVTVRTMSPHG-----ESSDSIP-------- 1067
Query 620 AIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSK 679
PV A + C + R P V P +A SP
Sbjct 1068 ---APVAPALASACQPARMSCLSPRPS------PEVRTP----LASVSPGLGDTSFPLRH 1114
Query 680 DQMYSDGNFTDVSVVEIE--ANDKKPFP-------EDLKSLDLFKKEKINTEGH------ 724
+ +F+ +E+ ++ P P ++S+ K+ T G
Sbjct 1115 PVPHGTQDFSASLSIEMSKGPQEEPPVPCSQEEAGAAVRSISEEKRAIEPTLGQEGPEPV 1174
Query 725 --SSGIGGSSCMSSSRPSISSSDENESSQNTSS 755
S C S + S + E +Q S
Sbjct 1175 APSLAKQEVECTSGDAGPVPCSTQGELTQKKPS 1207
Score = 47.2 bits (110), Expect = 9e-04, Method: Composition-based stats.
Identities = 46/358 (13%), Positives = 100/358 (28%), Gaps = 49/358 (14%)
Query 112 EQNVYGITIISGLPPEK---------PKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKS 162
E+ G + PPE P++++ + + W+ E F +
Sbjct 764 EEEAAGDELSLSPPPEGLGEPLAVPYPRHITVLKQLAHSVVLAWELPPERVDLRGFHIFV 823
Query 163 EWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 222
+ P ++ + + V V+A + G +SD +
Sbjct 824 NGELRQA----LGPGVPPKAVLENMDLRTGPLHVSVQALTSKG--SSDPLRCCLAVGAGA 877
Query 223 NP-PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P L + ++ ++ W + L + I ++ +
Sbjct 878 GVVPSQLRIHRL--TATSAEIAWVPGNSN----LAHAIYLNGEECPP--------ARPST 923
Query 282 SSFTVQDLKPFTEYVFRIRCM-KEDGKGY--WSDWSEEASGITYEDRPSKAPSFWYKIDP 338
T +L+P T Y R+ G W + A+ + + P+ P +
Sbjct 924 YWATFCNLRPGTLYQARVEAQIPSQGPWEPGWERPEQRAATLQFTTLPAGLPDAPLDVQA 983
Query 339 SHTQGYRTVQLVWKTLPP---FEANG-KILDYEVTLTRWKSHLQNYTVNATKLT----VN 390
+ + W + +NG ++ Y + K + L +
Sbjct 984 EPGPSPGILMISWLPVTIDAAGTSNGVRVTGYAIYADGQKIMEVASPTAGSVLVEVSQLQ 1043
Query 391 LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE 448
L + T+ + G+S ++ A A M + E
Sbjct 1044 LLQACHEVTVRTMSPHGESSDSI--------PAPVAPALASACQPARMSCLSPRPSPE 1093
>sp|Q865Y3|IL12B_PAPAN Interleukin-12 subunit beta OS=Papio anubis
OX=9555 GN=IL12B PE=2 SV=1
Length=328
Score = 51.8 bits (122), Expect = 1e-05, Method: Composition-based stats.
Identities = 42/226 (19%), Positives = 73/226 (32%), Gaps = 35/226 (15%)
Query 112 EQNVYGITIISGLPPEKPKN---LSCIV-NEGKKMRCEWDGGRETHLETNFTLKSEWATH 167
E ++ ++ ++PKN L C N + C W T L + +
Sbjct 108 EDGIWSTDVLKDQ--KEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSNP 165
Query 168 KFADC-------------KAKRDTPTSCTVDYS---TVYFVNIEVWVEAENALGKVTSDH 211
+ C + + C D + + IEV V+A + L K +
Sbjct 166 QGVTCGAVTLSAERVRGDNKEYEYSVECQEDSACPAAEERLPIEVMVDAIHKL-KYENYT 224
Query 212 INFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNP----SIKSVIILKYNIQYRTKDAS 267
+F +KP+PP NL + + S +++W P + S L + IQ + K
Sbjct 225 SSFFIRDIIKPDPPKNLQLKPL-KNSRQAEVSWEYPDTWSTPHSYFSLTFCIQVQGKSKR 283
Query 268 TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDW 313
D S F ++ WS+W
Sbjct 284 EKKDRIFTDKTSATVICR-------KNASFSVQAQDRYYSSSWSEW 322
>sp|Q04164|SAS_DROME Putative epidermal cell surface receptor
OS=Drosophila melanogaster OX=7227 GN=sas PE=2 SV=2
Length=1693
Score = 52.9 bits (125), Expect = 2e-05, Method: Composition-based stats.
Identities = 48/281 (17%), Positives = 81/281 (29%), Gaps = 36/281 (13%)
Query 427 VMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH-RTYLRGN 485
+ + L + W + +Y+ + + + +Y N
Sbjct 1411 PELTVSETNASWLQLTWKKLGDDQMEYVDGVQLRYKELTGMIYSSTPLIHRTLTSYTIQN 1470
Query 486 LAESKCYLITVTPVYADGPGSP----ESIKAYLKQAPPSKGPTVRT--KKVGKNEAVLEW 539
L Y I + + G G+ IK Q G V KV + W
Sbjct 1471 LQPDTGYEIGLYYIPLAGHGAELRAGHMIKVRTAQKVDVYGFDVTVNVTKVKTQSVEISW 1530
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNE----TAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
+ +P F+ Y Y++ G E V S T + L T Y + + Y
Sbjct 1531 NGVPYPEDK-FVHIYRAIYQSDAGKEDSSVFKVAKRDSTTGTLIMDLKPGTKYRLWLEMY 1589
Query 596 ---------------TDEGGKDGPEFTFTTPKFAQGEI------EAIVVPVCLAFLLTTL 634
T GG P T + +VV V A + +
Sbjct 1590 LTNGNTKKSNVVNFITKPGGPATPGKTGKLLTAGTDQPVGDYYGPLVVVSVIAALAIMST 1649
Query 635 LGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHN 675
L +L +R + + ++ P KS A +P
Sbjct 1650 LALLLIITRRRVHQTA---SITPPRKSDAAYDNPSYKVEIQ 1687
Score = 52.2 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 27/135 (20%), Positives = 50/135 (37%), Gaps = 6/135 (4%)
Query 226 HNLSVINSEELSSILKLTWTN-PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
+ + SE +S L+LTW + + ++Y+ +S P T +S+
Sbjct 1409 EDPELTVSETNASWLQLTWKKLGDDQMEYVDGVQLRYKELTGMIYSSTPLIH--RTLTSY 1466
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGY 344
T+Q+L+P T Y + + G G T + + TQ
Sbjct 1467 TIQNLQPDTGYEIGLYYIPLAGHGAELRAGHMIKVRTAQKVDVYGFDVTVNVTKVKTQ-- 1524
Query 345 RTVQLVWKTLPPFEA 359
+V++ W +P E
Sbjct 1525 -SVEISWNGVPYPED 1538
Score = 49.5 bits (116), Expect = 2e-04, Method: Composition-based stats.
Identities = 52/338 (15%), Positives = 101/338 (30%), Gaps = 48/338 (14%)
Query 227 NLSVINSEEL-SSILKLTWTNPSIKSVIILKYNIQYRT---KDASTWSQI---PPED-TA 278
++ V E + +++ +T P + + + ++Y D STW Q PPED A
Sbjct 1282 DIEVHTLEAIDPRSIRIVFTVPQVYVNLHGRVELRYSNGPSNDTSTWEQQIFAPPEDLIA 1341
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+++ F + L+P + Y +I + D + S + T +R P + P
Sbjct 1342 TSQMEFDLPSLEPNSLYKVKITLILRDLNSQPT--SSIYTVKTPPERTITPPPPFPDYRP 1399
Query 339 SHTQGYRTV---------------QLVWKTLPPFEANGKILDYEVTLTRWK----SHLQN 379
++ V QL WK L + + ++ S
Sbjct 1400 DFQDIFKNVEDPELTVSETNASWLQLTWKKL-GDDQMEYVDGVQLRYKELTGMIYSSTPL 1458
Query 380 YTVNATKLTVNLTN--DRYLATLTVRNLVGKSDA-------AVLTIPACDFQATHPVMDL 430
T T+ Y L L G V T D +++
Sbjct 1459 IHRTLTSYTIQNLQPDTGYEIGLYYIPLAGHGAELRAGHMIKVRTAQKVDVYGFDVTVNV 1518
Query 431 KAFPKDNMLWVEWTTPRESVKKYILEWCVLSDK-----APCITDWQQEDGTVHRTYLRGN 485
+ + + W K++ + + + + D T L +
Sbjct 1519 TKVKTQS-VEISWNGVPYPEDKFVHIYRAIYQSDAGKEDSSVFKVAKRDSTTGT--LIMD 1575
Query 486 LAESKCYLITVTPVYADGPG-SPESIKAYLKQAPPSKG 522
L Y + + +G + K P+
Sbjct 1576 LKPGTKYRLWLEMYLTNGNTKKSNVVNFITKPGGPATP 1613
Score = 39.5 bits (90), Expect = 0.21, Method: Composition-based stats.
Identities = 24/170 (14%), Positives = 53/170 (31%), Gaps = 36/170 (21%)
Query 446 PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
P + + + + + + + L + Y + +T + D
Sbjct 1321 PSNDTSTWEQQIFAPPEDLIATSQMEFDLPS---------LEPNSLYKVKITLILRD-LN 1370
Query 506 SPESIKAYLKQAPPS-----------------------KGPTVRTKKVGKNEAVLEWDQL 542
S + Y + PP + P + + + L W +L
Sbjct 1371 SQPTSSIYTVKTPPERTITPPPPFPDYRPDFQDIFKNVEDPELTVSETNASWLQLTWKKL 1430
Query 543 PVDVQNGFIRNYTIFYRTIIG--NETAVNVDSSHTEYTLSSLTSDTLYMV 590
D Q ++ + Y+ + G + + + T YT+ +L DT Y +
Sbjct 1431 -GDDQMEYVDGVQLRYKELTGMIYSSTPLIHRTLTSYTIQNLQPDTGYEI 1479
Score = 38.3 bits (87), Expect = 0.50, Method: Composition-based stats.
Identities = 17/105 (16%), Positives = 41/105 (39%), Gaps = 4/105 (4%)
Query 226 HNLSVINSEELSSILKLTWT-NPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
+++V ++ + ++++W P + + Y Y++ S + + +
Sbjct 1512 FDVTVNVTKVKTQSVEISWNGVPYPEDKFVHIYRAIYQSDAGKEDSSVFKVAKRDSTTGT 1571
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
+ DLKP T+Y + +G + S + IT P+
Sbjct 1572 LIMDLKPGTKYRLWLEMYLTNGN---TKKSNVVNFITKPGGPATP 1613
>sp|K7NAJ3|IRA1B_ONCMY Interferon alpha/beta receptor 1b OS=Oncorhynchus
mykiss OX=8022 GN=ifnar1b PE=2 SV=1
Length=388
Score = 52.2 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 61/367 (17%), Positives = 102/367 (28%), Gaps = 34/367 (9%)
Query 421 FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI---LEWCVLSDKAPCITDWQQEDGTV 477
+L + + W + + + +E+ +W +
Sbjct 2 LAELPQPQNLTLLTLNTQYVLTWDWDQTTTGNSVSFTVEYMAKYKMKMKKKNWSRVCERT 61
Query 478 HRT---YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNE 534
RT +L Y++ V ADG S K + S GP R +
Sbjct 62 TRTRCDLTGSDLHYLGMYVLRVRA-SADGVDSDWVNKDFCPDIDASLGPPSRAELAPVGN 120
Query 535 AV-LEWDQLPVDVQNGFIRN-----YTIFY--RTIIGNETAVNVDSSHTEYTLSS-LTSD 585
+ + Q+ + Y I Y R+ V S L +
Sbjct 121 LLDVTISDPLTSTQHSMKEHVLFLYYRILYWSRSDDPQGLKPKVLDSSNNLVTPPELEAW 180
Query 586 TLYMVRMAA----YTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCF 641
Y V + + Y P+ T G+I + + L LL F
Sbjct 181 AWYCVMIQSRYDYYNKTSSYTEPQCMQTEGDTPYGQIFLYFLVSMMVCFLLVLLSSYAFF 240
Query 642 NKRDLIKKHIWPNVPDPSK-------SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVV 694
+K +P++ P+ S P S+ ++ D VV
Sbjct 241 RFYRGLKNTFYPSIQLPAHIQEYLCDSSPGSDMPRLITAD---SEAELCCDKLTICPEVV 297
Query 695 EIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGI----GGSSCMSSSRPSISSSDENESS 750
+E + P L+ I + SGI GGS+ S D+ S
Sbjct 298 LLEIHVPPPLTAPPSELEQDSGRHIRQDSGDSGIYSTEGGSAQQGRSGGEPIRRDQEVDS 357
Query 751 QNTSSTV 757
T V
Sbjct 358 WQTLEQV 364
>sp|Q8IUI8|CRLF3_HUMAN Cytokine receptor-like factor 3 OS=Homo
sapiens OX=9606 GN=CRLF3 PE=1 SV=2
Length=442
Score = 51.8 bits (122), Expect = 2e-05, Method: Composition-based stats.
Identities = 22/104 (21%), Positives = 40/104 (38%), Gaps = 8/104 (8%)
Query 219 KVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTA 278
V PP + + E + + W Y +Q+R ++ + +
Sbjct 176 TVASRPP--VQIEELIEKPGGIIVRWCK-VDDDFTAQDYRLQFRKCTSNHFEDVY----V 228
Query 279 STRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ + F V + P +Y FR+ C + DG+ WS WS G +
Sbjct 229 GSETEFIVLHIDPNVDYQFRV-CARGDGRQEWSPWSVPQIGHST 271
Score = 44.5 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 17/104 (16%), Positives = 38/104 (37%), Gaps = 8/104 (8%)
Query 515 KQAPPSKGPTVRTKKV--GKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS 572
K + P V+ +++ ++ W ++ D ++Y + +R N
Sbjct 173 KHGTVASRPPVQIEELIEKPGGIIVRWCKVDDDF---TAQDYRLQFRKCTSNHFEDVYVG 229
Query 573 SHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG 616
S TE+ + + + Y R+ A D + P + P+
Sbjct 230 SETEFIVLHIDPNVDYQFRVCARGDGRQEWSPW---SVPQIGHS 270
>sp|Q9V4C8|HCF_DROME Host cell factor OS=Drosophila melanogaster
OX=7227 GN=Hcf PE=1 SV=2
Length=1500
Score = 52.2 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 24/144 (17%), Positives = 45/144 (31%), Gaps = 22/144 (15%)
Query 483 RGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP--PSKGPTVRTKKVGKNEAVLEWD 540
R NL Y ++ + + G G I ++ P P ++ K K A L W+
Sbjct 1306 RTNLEPGTAYRFRLSAINSCGRGEWGEISSFKTCLPGFPGAPSAIKISKDVKEGAHLTWE 1365
Query 541 QLPVDVQNGFIRNYTIFY-------------------RTIIGNETAVNVDSSHTEYTLSS 581
P I Y+++ R +G V ++
Sbjct 1366 PPPAQKTK-EIIEYSVYLAVKPTAKDKALSTPQLAFVRVYVGAANQCTVPNASLSNAHVD 1424
Query 582 LTSDTLYMVRMAAYTDEGGKDGPE 605
++ + R+AA +G +
Sbjct 1425 CSNKPAIIFRIAARNQKGYGPATQ 1448
Score = 49.1 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 20/84 (24%), Positives = 34/84 (40%), Gaps = 8/84 (10%)
Query 287 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRT 346
+L+P T Y FR+ + G+G W + S + + P + D
Sbjct 1307 TNLEPGTAYRFRLSAINSCGRGEWGEISSFKTCLP--GFPGAPSAIKISKDVKEGAH--- 1361
Query 347 VQLVWKTLPPFEANGKILDYEVTL 370
L W+ PP + +I++Y V L
Sbjct 1362 --LTWEP-PPAQKTKEIIEYSVYL 1382
Score = 41.0 bits (94), Expect = 0.066, Method: Composition-based stats.
Identities = 21/162 (13%), Positives = 41/162 (25%), Gaps = 29/162 (18%)
Query 392 TNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD--NMLWVEWTTPRES 449
Y L+ N G+ + ++ KD + W P
Sbjct 1311 PGTAYRFRLSAINSCGRGEWGEISSFKTCLPGFPGAPSAIKISKDVKEGAHLTWEPPPAQ 1370
Query 450 VKKYILEWCVLSDKAPCITDWQQEDG--------------------TVHRTYLRGNLAES 489
K I+E+ V P D ++ ++ + +
Sbjct 1371 KTKEIIEYSVYLAVKPTAKDKALSTPQLAFVRVYVGAANQCTVPNASLSNAHVDCSNKPA 1430
Query 490 KCYLITVTPVYADGPGSPESIK-----AYLKQAPPSKGPTVR 526
+ G G ++ A KQ P+ P ++
Sbjct 1431 II--FRIAARNQKGYGPATQVRWLQDPAAAKQHTPTVTPNLK 1470
>sp|Q9QUS6|TRIM1_MOUSE Probable E3 ubiquitin-protein ligase MID2
OS=Mus musculus OX=10090 GN=Mid2 PE=2 SV=2
Length=705
Score = 51.4 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 24/117 (21%), Positives = 41/117 (35%), Gaps = 22/117 (19%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS-------- 267
Y PNPP + + + + + W S I Y +QY
Sbjct 396 LDYLTAPNPPSIREELCTASHDT-ITVHWI--SDDEFSISSYELQYTIFTGQANFISLYN 452
Query 268 ---TWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+W +P ++ +TV L+ T Y+F ++ + + G S SE T
Sbjct 453 SVDSWMIVP----NIKQNHYTVHGLQSGTRYIFIVKAINQAG----SRNSEPTRLKT 501
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 18/118 (15%), Positives = 36/118 (31%), Gaps = 7/118 (6%)
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRE-SVKKYILEWCVLSDKAP------CITDWQQ 472
+ + + + V W + E S+ Y L++ + + +A + W
Sbjct 400 TAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTIFTGQANFISLYNSVDSWMI 459
Query 473 EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKV 530
Y L Y+ V + G + E + P P + KK+
Sbjct 460 VPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKL 517
Score = 43.3 bits (100), Expect = 0.011, Method: Composition-based stats.
Identities = 18/105 (17%), Positives = 34/105 (32%), Gaps = 14/105 (13%)
Query 517 APPSKGPTVR--TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIF---------YRTIIGNE 565
P+ P++R + + W + + YTIF Y ++
Sbjct 400 TAPN-PPSIREELCTASHDTITVHWISDDEFSISSYELQYTIFTGQANFISLYNSVDS-- 456
Query 566 TAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ + YT+ L S T Y+ + A G ++ T
Sbjct 457 WMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKT 501
>sp|G5EC23|HCF1_CAEEL Host cell factor homolog hcf-1 OS=Caenorhabditis
elegans OX=6239 GN=hcf-1 PE=1 SV=1
Length=782
Score = 51.4 bits (121), Expect = 4e-05, Method: Composition-based stats.
Identities = 29/143 (20%), Positives = 41/143 (29%), Gaps = 31/143 (22%)
Query 292 FTEYVFRIRCMKEDGKGYWSD-WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLV 350
Y FR+ + GKG WS+ S + Y PS +I SH QL
Sbjct 609 GQSYRFRVSAINGLGKGAWSETASCKTCVPGYPSAPSS-----IRITKSHEGA----QLT 659
Query 351 WKTLPPFEANGKILDYEVTLTRWKSHLQNYTVN---------------------ATKLTV 389
W+ +GKI++Y V L + T
Sbjct 660 WEPPSNTNISGKIIEYSVYLAVKNQSANSADSQLAFMRVYCGPQADCQVLQSNLGTAFVD 719
Query 390 NLTNDRYLATLTVRNLVGKSDAA 412
+ + RN G A
Sbjct 720 QTNKPAIIFRIAARNEKGYGPAT 742
Score = 47.5 bits (111), Expect = 6e-04, Method: Composition-based stats.
Identities = 30/136 (22%), Positives = 48/136 (35%), Gaps = 23/136 (17%)
Query 192 VNIEVWVEAENALGKVT-SDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+ V A N LGK S+ + P+ P ++ + S E + +LTW PS
Sbjct 610 QSYRFRVSAINGLGKGAWSETASCKTCVPGYPSAPSSIRITKSHEGA---QLTWEPPSNT 666
Query 251 S--VIILKYNIQYRTKDASTWSQ------IPPEDTASTRSSFTVQDL---------KPFT 293
+ I++Y++ K+ S S + +L KP
Sbjct 667 NISGKIIEYSVYLAVKNQSANSADSQLAFMRVYCGPQADCQVLQSNLGTAFVDQTNKPAI 726
Query 294 EYVFRIRCMKEDGKGY 309
+FRI E G G
Sbjct 727 --IFRIAARNEKGYGP 740
Score = 46.8 bits (109), Expect = 9e-04, Method: Composition-based stats.
Identities = 24/139 (17%), Positives = 45/139 (32%), Gaps = 20/139 (14%)
Query 486 LAESKCYLITVTPVYADGPGSPESIKAYLK--QAPPSKGPTVRTKKVGKNEAVLEWDQLP 543
L + Y V+ + G G+ + PS ++R K + A L W+
Sbjct 606 LINGQSYRFRVSAINGLGKGAWSETASCKTCVPGYPSAPSSIRITKSHEG-AQLTWEPPS 664
Query 544 VDVQNGFIRNYTIF-----------------YRTIIGNETAVNVDSSHTEYTLSSLTSDT 586
+G I Y+++ R G + V S+ T+
Sbjct 665 NTNISGKIIEYSVYLAVKNQSANSADSQLAFMRVYCGPQADCQVLQSNLGTAFVDQTNKP 724
Query 587 LYMVRMAAYTDEGGKDGPE 605
+ R+AA ++G +
Sbjct 725 AIIFRIAARNEKGYGPATQ 743
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 20/161 (12%), Positives = 40/161 (25%), Gaps = 27/161 (17%)
Query 376 HLQNYTVNATKLTVN-----LTNDRYLATLTVRNLVGKSDAAVLTIPACDFQA-THPVMD 429
H VN + T + Y ++ N +GK +
Sbjct 587 HNAFKCVNDSVFTTEDKIPLINGQSYRFRVSAINGLGKGAWSETASCKTCVPGYPSAPSS 646
Query 430 LKAFPKDNMLWVEWTTPRES-VKKYILEWCVLSDKAPCITDWQQEDGTVHRTY------- 481
++ + W P + + I+E+ V + R Y
Sbjct 647 IRITKSHEGAQLTWEPPSNTNISGKIIEYSVYLAVKNQSANSADSQLAFMRVYCGPQADC 706
Query 482 --LRGNLAESKCY---------LITVTPVYADGPGSPESIK 511
L+ NL + + + G G ++
Sbjct 707 QVLQSNL--GTAFVDQTNKPAIIFRIAARNEKGYGPATQVR 745
>sp|Q4R539|FSD1_MACFA Fibronectin type III and SPRY domain-containing
protein 1 OS=Macaca fascicularis OX=9541 GN=FSD1 PE=2
SV=2
Length=496
Score = 51.0 bits (120), Expect = 4e-05, Method: Composition-based stats.
Identities = 28/144 (19%), Positives = 56/144 (39%), Gaps = 30/144 (21%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYR---------TKDASTWSQI 272
P+ P + + S + + L W P + I Y ++YR K+ W I
Sbjct 165 PSAPV-IDLAESLVADNCVTLVWRMP-DEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVI 222
Query 273 PPEDTASTRSSFTVQDLKPFTEYV-FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
++ +T+ LK +Y+ FR++ + G +S+ +T E P+
Sbjct 223 EGIR----QTEYTLTGLKFDMKYMNFRVKACNKAVAGEFSEP------VTLET-----PA 267
Query 332 FWYKIDPSHTQGY---RTVQLVWK 352
F +++D S + + + W
Sbjct 268 FMFRLDASTSHQNLRVDDLSVEWD 291
>sp|Q9BTV5|FSD1_HUMAN Fibronectin type III and SPRY domain-containing
protein 1 OS=Homo sapiens OX=9606 GN=FSD1 PE=1 SV=1
Length=496
Score = 51.0 bits (120), Expect = 4e-05, Method: Composition-based stats.
Identities = 28/144 (19%), Positives = 56/144 (39%), Gaps = 30/144 (21%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYR---------TKDASTWSQI 272
P+ P + + S + + L W P + I Y ++YR K+ W I
Sbjct 165 PSAPV-IDLAESLVADNCVTLVWRMP-DEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVI 222
Query 273 PPEDTASTRSSFTVQDLKPFTEYV-FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPS 331
++ +T+ LK +Y+ FR++ + G +S+ +T E P+
Sbjct 223 EGIR----QTEYTLTGLKFDMKYMNFRVKACNKAVAGEFSEP------VTLET-----PA 267
Query 332 FWYKIDPSHTQGY---RTVQLVWK 352
F +++D S + + + W
Sbjct 268 FMFRLDASTSHQNLRVDDLSVEWD 291
>sp|Q9BXM9|FSD1L_HUMAN FSD1-like protein OS=Homo sapiens OX=9606
GN=FSD1L PE=1 SV=2
Length=530
Score = 50.6 bits (119), Expect = 5e-05, Method: Composition-based stats.
Identities = 27/150 (18%), Positives = 52/150 (35%), Gaps = 19/150 (13%)
Query 225 PHNLSVINSE--ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT----- 277
P + E + + + W P + I + +++R + ++ E
Sbjct 197 PKAPEIDPVECLVADNSVTVAWRMPEEDN-KIDHFILEHRKTNFDGLPRVKDERCWEIID 255
Query 278 ASTRSSFTVQDLKPFTEYV-FRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKI 336
+ +T+ LK ++Y+ FR+R + G +SD +T E +KA +F
Sbjct 256 NIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDP------VTLE---TKALNFNLDN 306
Query 337 DPSHTQGYRTVQ-LVWKTLPPFEANGKILD 365
SH + W KI
Sbjct 307 SSSHLNLKVEDTCVEWDPTGGKGQESKIKG 336
>sp|Q3V0F0|RIMB3_MOUSE RIMS-binding protein 3 OS=Mus musculus
OX=10090 GN=Rimbp3 PE=1 SV=2
Length=1606
Score = 51.0 bits (120), Expect = 5e-05, Method: Composition-based stats.
Identities = 38/211 (18%), Positives = 69/211 (33%), Gaps = 31/211 (15%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P L + N ++ +TW + S V+ L T S
Sbjct 981 LAPMELQLQNV--TATSATITWASGSNRYPHVVYLDDE--------------EHILTPSG 1024
Query 281 RSSFTVQDLKPFTEYVFRIRCM--KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDP 338
+ +T Q L P T Y R+ ++ + W S + T P P +
Sbjct 1025 VNHYTFQGLHPGTCYRVRVGVQLPRDLLQVLWETTSSTLTFDTPLAGPPDPP---LDVLV 1081
Query 339 SHTQGYRTVQLVWKTL---PPFEANG-KILDYEVTLTRWK-SHLQNYTVNATKLTV---N 390
H + + W + +NG ++ Y V + +K + + + T T L
Sbjct 1082 EHHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYVDGFKVTEVADATAGNTLLEFSQLQ 1141
Query 391 LTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
+ ++ +L G+S +V DF
Sbjct 1142 VPLSCQKVSVRTMSLYGESLDSVPAQIPEDF 1172
Score = 41.0 bits (94), Expect = 0.071, Method: Composition-based stats.
Identities = 28/195 (14%), Positives = 55/195 (28%), Gaps = 16/195 (8%)
Query 128 KPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYS 187
P L W G + + + H T
Sbjct 982 APMELQLQNVTATSATITWASGSNRYPHVVYL---DDEEHILTPSGVNHYTFQGLHPGTC 1038
Query 188 TVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN- 246
V +++ + L + TS + FD P+PP ++ V + +L ++W
Sbjct 1039 YRVRVGVQLPRDLLQVLWETTSSTLTFDTPLAGPPDPPLDVLVEH-HASPGVLVVSWLPV 1097
Query 247 -----PSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLK-PFTEYVFRIR 300
S V + Y + + D + + L+ P + +R
Sbjct 1098 TIDSAGSSNGVQVTGYAV-----YVDGFKVTEVADATAGNTLLEFSQLQVPLSCQKVSVR 1152
Query 301 CMKEDGKGYWSDWSE 315
M G+ S ++
Sbjct 1153 TMSLYGESLDSVPAQ 1167
Score = 37.5 bits (85), Expect = 0.68, Method: Composition-based stats.
Identities = 13/73 (18%), Positives = 22/73 (30%), Gaps = 10/73 (14%)
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTL 579
++ + V A + W + Y + +E + S YT
Sbjct 981 LAPMELQLQNVTATSATITWASGSNRYP-------HVVY---LDDEEHILTPSGVNHYTF 1030
Query 580 SSLTSDTLYMVRM 592
L T Y VR+
Sbjct 1031 QGLHPGTCYRVRV 1043
>sp|P26952|IL3RA_MOUSE Interleukin-3 receptor subunit alpha OS=Mus
musculus OX=10090 GN=Il3ra PE=1 SV=1
Length=396
Score = 50.2 bits (118), Expect = 6e-05, Method: Composition-based stats.
Identities = 45/288 (16%), Positives = 76/288 (26%), Gaps = 45/288 (16%)
Query 96 SLNIQLTCNILTFGQLEQNVYGITIISGLPPEKP-------KNLSCIVNEGKKMRCEWDG 148
S C++ F + PP+ ++L C V+E ++ C+W+
Sbjct 80 SFQSLSLCHVTNFTVFLGKDRAVAGSIQFPPDDDGDHEAAAQDLRCWVHE-GQLSCQWER 138
Query 149 GRETHLETNFTLKSEWA------THKFADC---------KAKRDTPTSCTVDYSTVY--- 190
G + + ++ + + A CT+D TV
Sbjct 139 GPKATGDVHYRMFWRDVRLGPAHNRECPHYHSLDVNTAGPAPHGGHEGCTLDLDTVLGST 198
Query 191 ------FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTW 244
+ + V G V D PP + E S W
Sbjct 199 PNSPDLVPQVTITVNGSGRAGPVPCMDNTVDLQRAEVLAPPT----LTVECNGSEAHARW 254
Query 245 TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKE 304
+ +L Y +Q S + F V + + FR++ E
Sbjct 255 VARNRFHHGLLGYTLQVNQSSRSEPQEYNVSI-----PHFWVPNAGAIS---FRVKSRSE 306
Query 305 DGKGYWSDWSEEASGI-TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
S WSE + E P K L+W
Sbjct 307 VYPRKLSSWSEAWGLVCPPEVMPVKTALVTSVATVLGAGLVAAGLLLW 354
>sp|O95153|RIMB1_HUMAN Peripheral-type benzodiazepine receptor-associated
protein 1 OS=Homo sapiens OX=9606 GN=TSPOAP1 PE=1
SV=2
Length=1857
Score = 50.6 bits (119), Expect = 7e-05, Method: Composition-based stats.
Identities = 37/240 (15%), Positives = 60/240 (25%), Gaps = 43/240 (18%)
Query 342 QGYRTVQLVWKTLPPFEA--------NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTN 393
Q +V L W+ P NG++ K+ L+N + A L
Sbjct 802 QLAHSVVLAWEPPPEQVELHGFHICVNGELRQALGPGAPPKAVLENLDLWAGPL------ 855
Query 394 DRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKY 453
++ G SD + P + W ++
Sbjct 856 ---HISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEITWVPGNSNLAHA 912
Query 454 ILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTP-VYADGPGSP----- 507
I A T W +L Y V + GP P
Sbjct 913 IYLNGEECPPASPSTYW----------ATFCHLRPGTPYQAQVEAQLPPQGPWEPGWERL 962
Query 508 -----ESIKAYLKQAPPSKGPTVRTKK-VGKNEAVLEWDQLPVDVQ---NGF-IRNYTIF 557
L PP V+ + ++ W + +D NG + Y I+
Sbjct 963 EQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYAIY 1022
Score = 47.2 bits (110), Expect = 0.001, Method: Composition-based stats.
Identities = 45/322 (14%), Positives = 96/322 (30%), Gaps = 41/322 (13%)
Query 123 GLPPEKP--KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKR---- 176
G PP P + L + + W+ E H + + ++
Sbjct 786 GEPPAVPYPRRLVVLKQLAHSVVLAWEPPPEQV--------ELHGFHICVNGELRQALGP 837
Query 177 DTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNP-PHNLSVINSEE 235
P ++ ++ + + V+A + G +SD + + P L V
Sbjct 838 GAPPKAVLENLDLWAGPLHISVQALTSRG--SSDPLRCCLAVGARAGVVPSQLRVHRL-- 893
Query 236 LSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
++ ++TW + L + I ++ + + T L+P T Y
Sbjct 894 TATSAEITWVPGNSN----LAHAIYLNGEECPP--------ASPSTYWATFCHLRPGTPY 941
Query 296 VFRIRCM-KEDGKGY--WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWK 352
++ G W + A+ + + P+ P + + + W
Sbjct 942 QAQVEAQLPPQGPWEPGWERLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWL 1001
Query 353 TLPP---FEANG-KILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLAT--LTVRNLV 406
+ +NG ++ Y + K + L + VR +
Sbjct 1002 PVTIDAAGTSNGVRVTGYAIYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMS 1061
Query 407 GKSDAAVLTIPACDFQATHPVM 428
++A +IPA A P
Sbjct 1062 PHGESA-DSIPAPITPALAPAS 1082
Score = 40.6 bits (93), Expect = 0.089, Method: Composition-based stats.
Identities = 29/199 (15%), Positives = 55/199 (28%), Gaps = 20/199 (10%)
Query 409 SDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCIT 468
S + +P + + + + W P E V+ + CV + +
Sbjct 777 SLSPSPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPEQVELHGFHICVNGELRQALG 836
Query 469 DWQQEDGTVHRTYLRG-NLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRT 527
G + L +L I+V + + G P + +R
Sbjct 837 -----PGAPPKAVLENLDLWAGPL-HISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRV 890
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTL 587
++ A + W N + + I+ + E S T L T
Sbjct 891 HRLTATSAEITWVP-----GNSNLAH-AIY----LNGEECPPASPSTYWATFCHLRPGTP 940
Query 588 YMVRMAAYTDEGGKDGPEF 606
Y ++ A GP
Sbjct 941 YQAQVEAQL---PPQGPWE 956
>sp|Q80WG7|TRI36_MOUSE E3 ubiquitin-protein ligase Trim36 OS=Mus
musculus OX=10090 GN=Trim36 PE=1 SV=2
Length=729
Score = 49.9 bits (117), Expect = 1e-04, Method: Composition-based stats.
Identities = 15/117 (13%), Positives = 35/117 (30%), Gaps = 4/117 (3%)
Query 405 LVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK-YILEWCVLSDK 463
+ K + + P ++ + N ++W P + Y+LE+ ++
Sbjct 399 NISKQTEVLGELSFFSSGIDIPEINEEQSKVYNNALIDWHHPEKDKADSYVLEYRKINRD 458
Query 464 APCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPP 519
+ W + + + NL + Y V + + AP
Sbjct 459 EE-MISWNEIEVHGTS-KVVSNLESNSPYAFRVRAYRGSICSPCSRELILHTPPAPV 513
Score = 44.1 bits (102), Expect = 0.007, Method: Composition-based stats.
Identities = 20/83 (24%), Positives = 34/83 (41%), Gaps = 8/83 (10%)
Query 533 NEAVLEWDQLPVDVQNGFIRNY-TIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVR 591
N A+++W D + ++ Y I + + + V T +S+L S++ Y R
Sbjct 431 NNALIDWHHPEKDKADSYVLEYRKINRDEEMISWNEIEVHG--TSKVVSNLESNSPYAFR 488
Query 592 MAAYTDEGGKDGP---EFTFTTP 611
+ AY G P E TP
Sbjct 489 VRAY--RGSICSPCSRELILHTP 509
Score = 42.5 bits (98), Expect = 0.022, Method: Composition-based stats.
Identities = 17/84 (20%), Positives = 29/84 (35%), Gaps = 6/84 (7%)
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRC 301
+ W +P Y ++YR + I + +S V +L+ + Y FR+R
Sbjct 435 IDWHHPEKDKAD--SYVLEYRKINRDE-EMISWNEIEVHGTSKVVSNLESNSPYAFRVRA 491
Query 302 MKEDGKGYWSDWSEEASGITYEDR 325
+ S S E T
Sbjct 492 YRGSIC---SPCSRELILHTPPAP 512
>sp|Q9FIE3|VIN3_ARATH Protein VERNALIZATION INSENSITIVE 3 OS=Arabidopsis
thaliana OX=3702 GN=VIN3 PE=1 SV=2
Length=620
Score = 49.9 bits (117), Expect = 1e-04, Method: Composition-based stats.
Identities = 25/108 (23%), Positives = 41/108 (38%), Gaps = 5/108 (5%)
Query 524 TVRTKKVGKNEAVLEWD-QLPVDVQNGFIRNYTIFYRTIIGNETAVN----VDSSHTEYT 578
TVR +++ + D + P I + +F R E + V T
Sbjct 317 TVRVEEIQARSVTVRVDSEEPSSSTQNKITGFRLFCRKSKDEECSSQGNCVVYLPETTSA 376
Query 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVC 626
+ L DT + +R+ ++ +EG D E FTT K E P+
Sbjct 377 IQGLEPDTEFCLRVVSFNEEGDLDESELRFTTLKDDGDEAGDQQSPLT 424
>sp|Q91ZY8|TRIM9_RAT E3 ubiquitin-protein ligase TRIM9 OS=Rattus
norvegicus OX=10116 GN=Trim9 PE=1 SV=1
Length=710
Score = 49.5 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 20/122 (16%), Positives = 34/122 (28%), Gaps = 11/122 (9%)
Query 513 YLKQAPPSKGPTVRTKKVG-----KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA 567
+++ S P ++ N A L W Q P+ Y + G +
Sbjct 431 FVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVAAD--GYILELDDGSGGQFR 488
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
T T+ L ++ Y R+ A+ G T E+
Sbjct 489 EVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYS----KTLVLQTSEVAWFAFDPGS 544
Query 628 AF 629
A
Sbjct 545 AH 546
Score = 46.4 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 20/120 (17%), Positives = 41/120 (34%), Gaps = 11/120 (9%)
Query 210 DHINFDPVYKVKPNPPHN----LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD 265
I+ +VK + P L + ++ L+W P + +V Y ++
Sbjct 424 QSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVAADGYILELDDGS 483
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
+ ++ + TV L + Y R++ + G S +S+ T E
Sbjct 484 GGQFREVY----VGKETMCTVDGLHFNSTYNARVKAFNKTGV---SPYSKTLVLQTSEVA 536
>sp|O48449|TUBE_BPSPP Tail tube protein gp17.1* OS=Bacillus phage
SPP1 OX=10724 GN=17.1 PE=1 SV=2
Length=264
Score = 48.3 bits (113), Expect = 1e-04, Method: Composition-based stats.
Identities = 18/106 (17%), Positives = 35/106 (33%), Gaps = 6/106 (6%)
Query 319 GITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQ 378
G T + P P + ++T +V + W + + Y V K
Sbjct 164 GQTTGEAPGTVPLPNAPQNLTYTATTDSVTVKWDAVEGAD------SYNVYRGAEKKLDA 217
Query 379 NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQAT 424
N T + LT + + + N G+S + + ++T
Sbjct 218 NVTTTSHTLTGIQPDTQLTVNVAAVNAGGESPMSQIVTKTLPAEST 263
Score = 46.4 bits (108), Expect = 6e-04, Method: Composition-based stats.
Identities = 21/102 (21%), Positives = 38/102 (37%), Gaps = 14/102 (14%)
Query 513 YLKQAP---PSK-GPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV 568
+AP P P T + ++WD + G +Y ++ G E +
Sbjct 166 TTGEAPGTVPLPNAPQNLTYTATTDSVTVKWDAV-----EG-ADSYNVY----RGAEKKL 215
Query 569 NVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ + + T +TL+ + DT V +AA G + T
Sbjct 216 DANVTTTSHTLTGIQPDTQLTVNVAAVNAGGESPMSQIVTKT 257
>sp|P23470|PTPRG_HUMAN Receptor-type tyrosine-protein phosphatase
gamma OS=Homo sapiens OX=9606 GN=PTPRG PE=1 SV=4
Length=1445
Score = 49.9 bits (117), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/112 (21%), Positives = 44/112 (39%), Gaps = 12/112 (11%)
Query 192 VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKS 251
N ++ EN LG S KV +PP ++ V + + L+++W+ P
Sbjct 326 WNHDMTDFLENPLGTEAS---------KVCSSPPIHMKVQPLNQ--TALQVSWSQPETIY 374
Query 252 VI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
I+ Y I Y + + T+ + P + Y+FR++ +
Sbjct 375 HPPIMNYMISYSWTKNEDEKEKTFTKDSDKDLKATISHVSPDSLYLFRVQAV 426
Score = 44.5 bits (103), Expect = 0.006, Method: Composition-based stats.
Identities = 16/80 (20%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV----DSSHT 575
S ++ + + + + W Q P + + I NY I Y +
Sbjct 348 SPPIHMKVQPLNQTALQVSWSQ-PETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDL 406
Query 576 EYTLSSLTSDTLYMVRMAAY 595
+ T+S ++ D+LY+ R+ A
Sbjct 407 KATISHVSPDSLYLFRVQAV 426
Score = 37.5 bits (85), Expect = 0.84, Method: Composition-based stats.
Identities = 12/80 (15%), Positives = 30/80 (38%), Gaps = 6/80 (8%)
Query 425 HPVMDLKAFPKD-NMLWVEWTTP----RESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
P + +K P + L V W+ P + Y++ + ++ + ++ +
Sbjct 348 SPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDLK 407
Query 480 TYLRGNLAESKCYLITVTPV 499
+ +++ YL V V
Sbjct 408 ATI-SHVSPDSLYLFRVQAV 426
>sp|A6QPL2|FNDC4_BOVIN Fibronectin type III domain-containing
protein 4 OS=Bos taurus OX=9913 GN=FNDC4 PE=2 SV=1
Length=230
Score = 47.9 bits (112), Expect = 1e-04, Method: Composition-based stats.
Identities = 17/99 (17%), Positives = 37/99 (37%), Gaps = 7/99 (7%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP ++V + ++ ++W P I++ Y+I + ++ I +T T +
Sbjct 43 PPSPVNVTVTHLRANSATVSWDVPEGN--IVIGYSISQQRQNGPGQRVIREVNT--TTRA 98
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ L ++Y ++R G S T
Sbjct 99 CALWGLAEDSDYTVQVR---SIGLRGESPPGPRVHFRTL 134
>sp|D3ZN95|HCFC1_RAT Host cell factor 1 OS=Rattus norvegicus OX=10116
GN=Hcfc1 PE=1 SV=1
Length=2034
Score = 49.9 bits (117), Expect = 1e-04, Method: Composition-based stats.
Identities = 32/188 (17%), Positives = 56/188 (30%), Gaps = 36/188 (19%)
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
T + Q+L+P T Y FR+ + G+G +S+ S + + P +
Sbjct 1854 GTVPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLP--GFPGAPCAIKIS 1911
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV------ 389
P L W+ PP +GKI++Y V L S ++T +
Sbjct 1912 KSPDGAH------LTWE--PPSVTSGKIIEYSVYLAIQSSQASGEPKSSTPAQLAFMRVY 1963
Query 390 --------------------NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMD 429
T + + RN G A + + +
Sbjct 1964 CGPSPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSKDSSGTKP 2023
Query 430 LKAFPKDN 437
P +
Sbjct 2024 ASKRPMSS 2031
Score = 47.9 bits (112), Expect = 5e-04, Method: Composition-based stats.
Identities = 29/152 (19%), Positives = 48/152 (32%), Gaps = 27/152 (18%)
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP--PSKGPTVRTKKVGKNEA 535
+ + L Y V + A G G I A+ P P ++ K + A
Sbjct 1859 YNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISK-SPDGA 1917
Query 536 VLEWDQLPVDVQNGFIRNYTIF----------------------YRTIIGNETAVNVDSS 573
L W+ P V +G I Y+++ R G + V SS
Sbjct 1918 HLTWE--PPSVTSGKIIEYSVYLAIQSSQASGEPKSSTPAQLAFMRVYCGPSPSCLVQSS 1975
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
T+ + R+AA ++G +
Sbjct 1976 SLSNAHIDYTTKPAIIFRIAARNEKGYGPATQ 2007
Score = 41.4 bits (95), Expect = 0.047, Method: Composition-based stats.
Identities = 35/167 (21%), Positives = 53/167 (32%), Gaps = 29/167 (17%)
Query 192 VNIEVWVEAENALGKVTSDHIN-FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+ V NA G+ I+ F P P + + S + + LTW PS+
Sbjct 1871 TAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPDGA---HLTWEPPSVT 1927
Query 251 SVIILKYNIQY---------RTKDASTWSQIPPEDTASTRSSFTVQ--DL-KPFTEYV-- 296
S I++Y++ K ++ S VQ L +Y
Sbjct 1928 SGKIIEYSVYLAIQSSQASGEPKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTK 1987
Query 297 ----FRIRCMKEDGKGYWSD--WSEEAS-----GITYEDRPSKAPSF 332
FRI E G G + W +E S RP +P
Sbjct 1988 PAIIFRIAARNEKGYGPATQVRWLQETSKDSSGTKPASKRPMSSPEM 2034
Score = 38.3 bits (87), Expect = 0.45, Method: Composition-based stats.
Identities = 27/238 (11%), Positives = 61/238 (26%), Gaps = 39/238 (16%)
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
E G S + P K + W+ + +V + LPP +A
Sbjct 1793 TEVANGIESLGVKPDLPPPPSKAPIKKENQWFDV---GVIKGTSVMVTHYFLPPDDA--- 1846
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
V + +Y N K Y + N G+ + ++
Sbjct 1847 -----VQSDDDSGTVPDY--NQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLP 1899
Query 423 ATH-PVMDLKAFPKDNMLWVEWTTPR---ESVKKYILEWCVLSDKAPCITDWQQ------ 472
+K + + W P + +Y + + S +A
Sbjct 1900 GFPGAPCAIKISKSPDGAHLTWEPPSVTSGKIIEYSVYLAIQSSQASGEPKSSTPAQLAF 1959
Query 473 -------------EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
+ ++ ++ + + G G ++ +L++
Sbjct 1960 MRVYCGPSPSCLVQSSSLSNAHIDYTTKPAII--FRIAARNEKGYGPATQVR-WLQET 2014
>sp|Q61191|HCFC1_MOUSE Host cell factor 1 OS=Mus musculus OX=10090
GN=Hcfc1 PE=1 SV=2
Length=2045
Score = 49.9 bits (117), Expect = 1e-04, Method: Composition-based stats.
Identities = 32/188 (17%), Positives = 56/188 (30%), Gaps = 36/188 (19%)
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
T + Q+L+P T Y FR+ + G+G +S+ S + + P +
Sbjct 1853 GTVPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLP--GFPGAPCAIKIS 1910
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV------ 389
P L W+ PP +GKI++Y V L S ++T +
Sbjct 1911 KSPDGAH------LTWE--PPSVTSGKIIEYSVYLAIQSSQASGEPKSSTPAQLAFMRVY 1962
Query 390 --------------------NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMD 429
T + + RN G A + + +
Sbjct 1963 CGPSPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSKDSSGTKP 2022
Query 430 LKAFPKDN 437
P +
Sbjct 2023 ASKRPMSS 2030
Score = 47.9 bits (112), Expect = 5e-04, Method: Composition-based stats.
Identities = 29/152 (19%), Positives = 48/152 (32%), Gaps = 27/152 (18%)
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP--PSKGPTVRTKKVGKNEA 535
+ + L Y V + A G G I A+ P P ++ K + A
Sbjct 1858 YNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISK-SPDGA 1916
Query 536 VLEWDQLPVDVQNGFIRNYTIF----------------------YRTIIGNETAVNVDSS 573
L W+ P V +G I Y+++ R G + V SS
Sbjct 1917 HLTWE--PPSVTSGKIIEYSVYLAIQSSQASGEPKSSTPAQLAFMRVYCGPSPSCLVQSS 1974
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
T+ + R+AA ++G +
Sbjct 1975 SLSNAHIDYTTKPAIIFRIAARNEKGYGPATQ 2006
Score = 41.4 bits (95), Expect = 0.048, Method: Composition-based stats.
Identities = 35/167 (21%), Positives = 53/167 (32%), Gaps = 29/167 (17%)
Query 192 VNIEVWVEAENALGKVTSDHIN-FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+ V NA G+ I+ F P P + + S + + LTW PS+
Sbjct 1870 TAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPDGA---HLTWEPPSVT 1926
Query 251 SVIILKYNIQY---------RTKDASTWSQIPPEDTASTRSSFTVQ--DL-KPFTEYV-- 296
S I++Y++ K ++ S VQ L +Y
Sbjct 1927 SGKIIEYSVYLAIQSSQASGEPKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTK 1986
Query 297 ----FRIRCMKEDGKGYWSD--WSEEAS-----GITYEDRPSKAPSF 332
FRI E G G + W +E S RP +P
Sbjct 1987 PAIIFRIAARNEKGYGPATQVRWLQETSKDSSGTKPASKRPMSSPEM 2033
Score = 38.7 bits (88), Expect = 0.38, Method: Composition-based stats.
Identities = 27/238 (11%), Positives = 61/238 (26%), Gaps = 39/238 (16%)
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
E G S + P K + W+ + +V + LPP +A
Sbjct 1792 TEVANGIESLGVKPDLPPPPSKAPVKKENQWFDV---GVIKGTSVMVTHYFLPPDDA--- 1845
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
V + +Y N K Y + N G+ + ++
Sbjct 1846 -----VQSDDDSGTVPDY--NQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLP 1898
Query 423 ATH-PVMDLKAFPKDNMLWVEWTTPR---ESVKKYILEWCVLSDKAPCITDWQQ------ 472
+K + + W P + +Y + + S +A
Sbjct 1899 GFPGAPCAIKISKSPDGAHLTWEPPSVTSGKIIEYSVYLAIQSSQASGEPKSSTPAQLAF 1958
Query 473 -------------EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
+ ++ ++ + + G G ++ +L++
Sbjct 1959 MRVYCGPSPSCLVQSSSLSNAHIDYTTKPAII--FRIAARNEKGYGPATQVR-WLQET 2013
>sp|Q8C7M3|TRIM9_MOUSE E3 ubiquitin-protein ligase TRIM9 OS=Mus
musculus OX=10090 GN=Trim9 PE=1 SV=2
Length=817
Score = 49.1 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 24/146 (16%), Positives = 46/146 (32%), Gaps = 17/146 (12%)
Query 210 DHINFDPVYKVKPNPPHN----LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD 265
I+ +VK + P L + ++ L+W P + +V Y ++
Sbjct 424 QSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVAADGYILELDDGS 483
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
+ ++ + TV L + Y R++ + G S +S+ T E
Sbjct 484 GGQFREVY----VGKETMCTVDGLHFNSTYNARVKAFNKTGV---SPYSKTLVLQTSEAA 536
Query 326 ------PSKAPSFWYKIDPSHTQGYR 345
P K + P R
Sbjct 537 GAHETKPMKDTDSEEQTLPFPVPSER 562
Score = 48.7 bits (114), Expect = 3e-04, Method: Composition-based stats.
Identities = 17/95 (18%), Positives = 30/95 (32%), Gaps = 7/95 (7%)
Query 513 YLKQAPPSKGPTVRTKKVG-----KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA 567
+++ S P ++ N A L W Q P+ Y + G +
Sbjct 431 FVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVAAD--GYILELDDGSGGQFR 488
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
T T+ L ++ Y R+ A+ G
Sbjct 489 EVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSP 523
>sp|Q5R3F8|PPR29_HUMAN Protein phosphatase 1 regulatory subunit
29 OS=Homo sapiens OX=9606 GN=ELFN2 PE=1 SV=1
Length=820
Score = 49.1 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 25/134 (19%), Positives = 43/134 (32%), Gaps = 14/134 (10%)
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTL 579
S GP ++ V A L + + Y Y + + + TL
Sbjct 294 SAGPAIKLHHVTFTSATLVVIIPHPYSKMYILVQYNNSYF-----SDVMTLKNKKEIVTL 348
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT---------PKFAQGEIEAIVVPVCLAFL 630
L + T Y + + + + TFTT P + + + CL +
Sbjct 349 DKLRAHTEYTFCVTSLRNSRRFNHTCLTFTTRDPVPGDLAPSTSTTTHYIMTILGCLFGM 408
Query 631 LTTLLGVLFCFNKR 644
+ L V +C KR
Sbjct 409 VIVLGAVYYCLRKR 422
>sp|P83097|WSCK_DROME Putative inactive tyrosine-protein kinase
Wsck OS=Drosophila melanogaster OX=7227 GN=Wsck PE=2 SV=2
Length=791
Score = 49.1 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 39/185 (21%), Positives = 70/185 (38%), Gaps = 26/185 (14%)
Query 211 HINFDPVYKVKPNPPHNLSVINSEELSSILKLTW-------------TNPSIKSVIILKY 257
H + + +P PH+L + N E S L L+W + + ++ +
Sbjct 119 HSYYSTILTKQPG-PHHLRISNKTENS--LTLSWNAYEARKLLLAGGAEAVLPNQLLDNF 175
Query 258 NIQ---YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
I+ +T + P ST + F + DL P T Y +R M +D + S+
Sbjct 176 LIKAQVLKTYSSLPAFPQPEFMVQSTETQFELTDLHPATLYNISVRAMCKDAQVGQSECG 235
Query 315 EEASGITYE-DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRW 373
+ + T E PS P+ + ++ RTV + + P NG + V +
Sbjct 236 QASIEATTEVGLPSPVPAQPKIL----SRTDRTVTI--ELSPIRNDNGPLSKLLVIVEYV 289
Query 374 KSHLQ 378
+ L
Sbjct 290 DNALS 294
Score = 44.1 bits (102), Expect = 0.006, Method: Composition-based stats.
Identities = 22/141 (16%), Positives = 43/141 (30%), Gaps = 26/141 (18%)
Query 435 KDNMLWVEWTT----------------PRESVKKYILEWCVL--SDKAPCITDWQQEDGT 476
+N L + W P + + ++++ VL P + +
Sbjct 141 TENSLTLSWNAYEARKLLLAGGAEAVLPNQLLDNFLIKAQVLKTYSSLPAFPQPEFMVQS 200
Query 477 VHRTYLRGNLAESKCYLITVTP-VYADGPGSPE----SIKAYLKQAPPSKGPT-VRTKKV 530
+ +L + Y I+V G E SI+A + PS P +
Sbjct 201 TETQFELTDLHPATLYNISVRAMCKDAQVGQSECGQASIEATTEVGLPSPVPAQPKILSR 260
Query 531 GKNEAVLEWDQLPVDVQNGFI 551
+ + P+ NG +
Sbjct 261 TDRTVTI--ELSPIRNDNGPL 279
Score = 37.9 bits (86), Expect = 0.52, Method: Composition-based stats.
Identities = 21/116 (18%), Positives = 36/116 (31%), Gaps = 20/116 (17%)
Query 498 PVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDV----------- 546
Y G G L + P +R +N L W+
Sbjct 110 AQYCGGVGVHSYYSTILTKQP--GPHHLRISNKTENSLTLSWNAYEARKLLLAGGAEAVL 167
Query 547 QNGFIRNYTIFYRTIIGNET-------AVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
N + N+ I + + + V S+ T++ L+ L TLY + + A
Sbjct 168 PNQLLDNFLIKAQVLKTYSSLPAFPQPEFMVQSTETQFELTDLHPATLYNISVRAM 223
>sp|P98161|PKD1_HUMAN Polycystin-1 OS=Homo sapiens OX=9606 GN=PKD1
PE=1 SV=3
Length=4303
Score = 49.5 bits (116), Expect = 2e-04, Method: Composition-based stats.
Identities = 46/291 (16%), Positives = 82/291 (28%), Gaps = 51/291 (18%)
Query 169 FADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL 228
+ C P T+ Y+ + V AEN +G + L
Sbjct 1582 WVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFVYVLQLI------EGL 1635
Query 229 SVINSEE---LSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFT 285
V+ + ++L ++ + Y + W P A + F+
Sbjct 1636 QVVGGGRYFPTNHTVQLQ---AVVRDGTNVSY-------SWTAWRDRGPA-LAGSGKGFS 1684
Query 286 VQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYR 345
+ L+ T Y ++R G S W++ T + P W + S
Sbjct 1685 LTVLEAGT-YHVQLRATNMLG----SAWAD----CTMDFV---EPVGWLMVAASPNPAAV 1732
Query 346 TVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNL 405
+ L A G + Y +L S + +L T+T N
Sbjct 1733 NTSVT---LSAELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGL---HLVTMTAGNP 1786
Query 406 VGKSDAAVLT-----IPACDFQATHPVMDLKAFPKD--------NMLWVEW 443
+G ++A V + +A+ P A V W
Sbjct 1787 LGSANATVEVDVQVPVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSW 1837
>sp|Q68FM6|PPR29_MOUSE Protein phosphatase 1 regulatory subunit
29 OS=Mus musculus OX=10090 GN=Elfn2 PE=1 SV=1
Length=823
Score = 49.1 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 39/256 (15%), Positives = 80/256 (31%), Gaps = 35/256 (14%)
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTL 579
S GP ++ +V A L + + Y Y + + + TL
Sbjct 294 SAGPAIKLHQVTFTSATLVVIIPHPYSKMYVLVQYNNSYF-----SDVMTLKNKKEIVTL 348
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT---------PKFAQGEIEAIVVPVCLAFL 630
L + T Y + + + + TFTT P + + + CL +
Sbjct 349 DKLRAHTEYTFCVTSLRNSRRFNHTCLTFTTRDLVPGDLAPSTSTTTHYIMTILGCLFGM 408
Query 631 LTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRH-NFNSKDQMYSDGNFT 689
+ L V +C KR + ++ KS + + + ++ +++
Sbjct 409 VIVLGAVYYCLRKRRMQEEKQ--------KSVNVKKTILEMRYGADVDAGSIVHAAQKLG 460
Query 690 DVSVVEIEANDKKP------FPEDLKSLDLFKKEKINTEGH----SSGIGGSSCMSSSR- 738
+ V+ + P P K+ T+G+ +G G S
Sbjct 461 EPPVLPVARMSSIPSMVGEKLPASKGLEAGLDTPKVATKGNYIEVRTGAAGDSLARPEEE 520
Query 739 -PSISSSDENESSQNT 753
P I + + + +T
Sbjct 521 LPEIENGQGSAAEIST 536
>sp|Q1LY10|FSD1_DANRE Fibronectin type III and SPRY domain-containing
protein 1 OS=Danio rerio OX=7955 GN=fsd1 PE=3 SV=1
Length=495
Score = 48.7 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 21/114 (18%), Positives = 42/114 (37%), Gaps = 20/114 (18%)
Query 210 DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDAST- 268
I F PV P P + V + + + + + WT P I Y +++R +
Sbjct 157 QSITFLPV----PATPE-IHVADCQVFDNTVTVVWTLPE-PDSKIDHYILEHRKTNHEGP 210
Query 269 --------WSQIPPEDTASTRSSFTVQDLKPFTEY-VFRIRCMKEDGKGYWSDW 313
W + + +T+ ++ T Y FR++ + G +S+
Sbjct 211 PRAREDYPWMVVEG----IKETEYTLTGVRFDTRYMTFRVKACNKAVAGEFSEP 260
>sp|Q9H6D8|FNDC4_HUMAN Fibronectin type III domain-containing
protein 4 OS=Homo sapiens OX=9606 GN=FNDC4 PE=2 SV=1
Length=234
Score = 47.5 bits (111), Expect = 2e-04, Method: Composition-based stats.
Identities = 17/99 (17%), Positives = 37/99 (37%), Gaps = 7/99 (7%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP ++V + ++ ++W P I++ Y+I + ++ I +T T +
Sbjct 47 PPSPVNVTVTHLRANSATVSWDVPEGN--IVIGYSISQQRQNGPGQRVIREVNT--TTRA 102
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ L ++Y ++R G S T
Sbjct 103 CALWGLAEDSDYTVQVR---SIGLRGESPPGPRVHFRTL 138
>sp|O70583|TRI18_MOUSE E3 ubiquitin-protein ligase Midline-1 OS=Mus
musculus OX=10090 GN=Mid1 PE=1 SV=2
Length=680
Score = 48.7 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 25/130 (19%), Positives = 46/130 (35%), Gaps = 35/130 (27%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRT------------ 263
Y PNPP + + + + + WT+ S ++ Y +QY
Sbjct 376 LDYLTAPNPPAIREELCTASYDT-ITVHWTSEDEFS--VVSYELQYTIFTGQANVVNVAC 432
Query 264 ------------KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWS 311
A +W +P ++ +TV L+ T+Y+F ++ + + G S
Sbjct 433 DGTCLLGSAGLCNSADSWMIVP----NIKQNHYTVHGLQSGTKYIFTVKAINQAG----S 484
Query 312 DWSEEASGIT 321
SE T
Sbjct 485 RSSEPGKLKT 494
Score = 42.2 bits (97), Expect = 0.023, Method: Composition-based stats.
Identities = 24/134 (18%), Positives = 38/134 (28%), Gaps = 20/134 (15%)
Query 420 DFQATHPVMDLKAFPKDNMLWVEWTTPRE-SVKKYILEW-----------------CVLS 461
+ + + + V WT+ E SV Y L++ C+L
Sbjct 380 TAPNPPAIREELCTASYDTITVHWTSEDEFSVVSYELQYTIFTGQANVVNVACDGTCLLG 439
Query 462 DKAPCIT--DWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPP 519
C + W Y L Y+ TV + G S E K P
Sbjct 440 SAGLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFTVKAINQAGSRSSEPGKLKTNSQPF 499
Query 520 SKGPTVRTKKVGKN 533
P +K+ +
Sbjct 500 RLDPKSAHRKLKVS 513
Score = 39.8 bits (91), Expect = 0.13, Method: Composition-based stats.
Identities = 18/113 (16%), Positives = 30/113 (27%), Gaps = 31/113 (27%)
Query 517 APPSKGPTVR--TKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV---- 570
P+ P +R + + W + +Y + Y G VNV
Sbjct 380 TAPN-PPAIREELCTASYDTITVHW----TSEDEFSVVSYELQYTIFTGQANVVNVACDG 434
Query 571 --------------------DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDG 603
+ YT+ L S T Y+ + A G +
Sbjct 435 TCLLGSAGLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFTVKAINQAGSRSS 487
>sp|Q3SWY4|LRN4L_BOVIN LRRN4 C-terminal-like protein OS=Bos taurus
OX=9913 GN=LRRN4CL PE=2 SV=2
Length=232
Score = 47.2 bits (110), Expect = 2e-04, Method: Composition-based stats.
Identities = 27/147 (18%), Positives = 45/147 (31%), Gaps = 26/147 (18%)
Query 519 PSKGPTVRTKKVGKN--EAVLEWDQLPVDVQNGFIRNY-TIFYRTIIGNETAVNVDSSHT 575
P P + +V + A + W + + Y + + + + +S+
Sbjct 77 PPHPPRLGEVRVEADMGRAEVHW-----CAPSSPVNQYWLLLWEGGGAPQKGPSFNSTVR 131
Query 576 EYTLSSLTSDTLYMVRMAAYTDEG-------------GKDGPEFT-----FTTPKFAQGE 617
L L Y+V + A D G DGP P+
Sbjct 132 RAELKGLNPGGAYVVCVVAANDAGESRAPGPGAEGLDSADGPNLGPCGRLTVPPRPLTLL 191
Query 618 IEAIVVPVCLAFLLTTLLGVLFCFNKR 644
A+ V LA L + L FC +R
Sbjct 192 HAAMGVGSALALLSCSALVWHFCLRQR 218
>sp|Q3TR08|FNDC4_MOUSE Fibronectin type III domain-containing
protein 4 OS=Mus musculus OX=10090 GN=Fndc4 PE=2 SV=1
Length=231
Score = 47.2 bits (110), Expect = 2e-04, Method: Composition-based stats.
Identities = 17/99 (17%), Positives = 37/99 (37%), Gaps = 7/99 (7%)
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
PP ++V + ++ ++W P I++ Y+I + ++ I +T T +
Sbjct 43 PPSPVNVTVTHLRANSATVSWDVPEGN--IVIGYSISQQRQNGPGQRVIREVNT--TTRA 98
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 322
+ L ++Y ++R G S T
Sbjct 99 CALWGLAEDSDYTVQVR---SIGLRGESPPGPRVHFRTL 134
>sp|Q9C026|TRIM9_HUMAN E3 ubiquitin-protein ligase TRIM9 OS=Homo
sapiens OX=9606 GN=TRIM9 PE=1 SV=1
Length=710
Score = 48.7 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 20/122 (16%), Positives = 34/122 (28%), Gaps = 11/122 (9%)
Query 513 YLKQAPPSKGPTVRTKKVG-----KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA 567
+++ S P ++ N A L W Q P+ Y + G +
Sbjct 431 FVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTV--PADGYILELDDGNGGQFR 488
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
T T+ L ++ Y R+ A+ G T E+
Sbjct 489 EVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYS----KTLVLQTSEVAWFAFDPGS 544
Query 628 AF 629
A
Sbjct 545 AH 546
Score = 48.3 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 20/120 (17%), Positives = 42/120 (35%), Gaps = 11/120 (9%)
Query 210 DHINFDPVYKVKPNPPHN----LSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKD 265
I+ +VK + P L + ++ L+W P + +V Y ++ +
Sbjct 424 QSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELDDGN 483
Query 266 ASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
+ ++ + TV L + Y R++ + G S +S+ T E
Sbjct 484 GGQFREVY----VGKETMCTVDGLHFNSTYNARVKAFNKTGV---SPYSKTLVLQTSEVA 536
>sp|Q6UWL2|SUSD1_HUMAN Sushi domain-containing protein 1 OS=Homo
sapiens OX=9606 GN=SUSD1 PE=1 SV=1
Length=747
Score = 48.3 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 41/336 (12%), Positives = 84/336 (25%), Gaps = 47/336 (14%)
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPED---TASTRSSFTVQDLKPFTEYVFR 298
+ W S + + Y I + + + E T +R+ L P T Y
Sbjct 312 VRWQINSRRINPKISYVISIKGQRLDPMESVREETVNLTTDSRTPEVCLALYPGTNYTVN 371
Query 299 IRCMKEDGKGYWSDWSEEA--SGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPP 356
I S A T E +D G + + +T
Sbjct 372 ISTAPP-------RRSMPAVIGFQTAE------------VDLLEDDGSFNISIFNETCLK 412
Query 357 FEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT- 415
+ + E + Y N + T R + +L +D V
Sbjct 413 LNRRSRKVGSEHMYQFTVLGQRWYLANFSHATSFNFTTREQVPVVCLDLYPTTDYTVNVT 472
Query 416 ---------IPACDFQATHPVMDLKAFPKDNMLWVEWTTPR--ESVKKYILE-WCVLSDK 463
+ + N + W + + + + Y+ W +
Sbjct 473 LLRSPKRHSVQITIATPPAVKQTISNISGFNETCLRWRSIKTADMEEMYLFHIWGQRWYQ 532
Query 464 APCITDWQ-QEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKG 522
+ + + +L Y +++ + ++ P I + P
Sbjct 533 KEFAQEMTFNISSSSRDPEVCLDLRPGTNYNVSLRALSSE---LPVVISLTTQITEPPLP 589
Query 523 PT--VRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTI 556
+ L +NG I +Y +
Sbjct 590 EVEFFTVHRGPLPRLRLR----KAKEKNGPISSYQV 621
>sp|P51610|HCFC1_HUMAN Host cell factor 1 OS=Homo sapiens OX=9606
GN=HCFC1 PE=1 SV=2
Length=2035
Score = 48.7 bits (114), Expect = 3e-04, Method: Composition-based stats.
Identities = 24/95 (25%), Positives = 39/95 (41%), Gaps = 10/95 (11%)
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
T + Q+L+P T Y FR+ + G+G +S+ S + + P +
Sbjct 1843 GTVPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLP--GFPGAPCAIKIS 1900
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTL 370
P L W+ PP +GKI++Y V L
Sbjct 1901 KSPDGAH------LTWE--PPSVTSGKIIEYSVYL 1927
Score = 48.3 bits (113), Expect = 4e-04, Method: Composition-based stats.
Identities = 29/152 (19%), Positives = 48/152 (32%), Gaps = 27/152 (18%)
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP--PSKGPTVRTKKVGKNEA 535
+ + L Y V + A G G I A+ P P ++ K + A
Sbjct 1848 YNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISK-SPDGA 1906
Query 536 VLEWDQLPVDVQNGFIRNYTIF----------------------YRTIIGNETAVNVDSS 573
L W+ P V +G I Y+++ R G + V SS
Sbjct 1907 HLTWE--PPSVTSGKIIEYSVYLAIQSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSS 1964
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
T+ + R+AA ++G +
Sbjct 1965 SLSNAHIDYTTKPAIIFRIAARNEKGYGPATQ 1996
Score = 41.8 bits (96), Expect = 0.042, Method: Composition-based stats.
Identities = 38/167 (23%), Positives = 54/167 (32%), Gaps = 29/167 (17%)
Query 192 VNIEVWVEAENALGKVTSDHIN-FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+ V NA G+ I+ F P P + + S + + LTW PS+
Sbjct 1860 TAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPDGA---HLTWEPPSVT 1916
Query 251 SVIILKYN----IQYRTKDASTWSQIPPEDTA-----STRSSFTVQD--L-KPFTEYV-- 296
S I++Y+ IQ S P + S VQ L +Y
Sbjct 1917 SGKIIEYSVYLAIQSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTK 1976
Query 297 ----FRIRCMKEDGKGYWSD--WSEEAS-----GITYEDRPSKAPSF 332
FRI E G G + W +E S RP +P
Sbjct 1977 PAIIFRIAARNEKGYGPATQVRWLQETSKDSSGTKPANKRPMSSPEM 2023
Score = 38.3 bits (87), Expect = 0.43, Method: Composition-based stats.
Identities = 27/238 (11%), Positives = 60/238 (25%), Gaps = 39/238 (16%)
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGK 362
E G S + P K + W+ + V + LPP +A
Sbjct 1782 TEVANGIESLGVKPDLPPPPSKAPMKKENQWFDV---GVIKGTNVMVTHYFLPPDDA--- 1835
Query 363 ILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQ 422
V + +Y N K Y + N G+ + ++
Sbjct 1836 -----VPSDDDLGTVPDY--NQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLP 1888
Query 423 ATH-PVMDLKAFPKDNMLWVEWTTPR---ESVKKYILEWCVLSDKAPCITDWQQ------ 472
+K + + W P + +Y + + S +A
Sbjct 1889 GFPGAPCAIKISKSPDGAHLTWEPPSVTSGKIIEYSVYLAIQSSQAGGELKSSTPAQLAF 1948
Query 473 -------------EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
+ ++ ++ + + G G ++ +L++
Sbjct 1949 MRVYCGPSPSCLVQSSSLSNAHIDYTTKPAII--FRIAARNEKGYGPATQVR-WLQET 2003
>sp|Q29RQ5|TRIM9_BOVIN E3 ubiquitin-protein ligase TRIM9 OS=Bos
taurus OX=9913 GN=TRIM9 PE=2 SV=1
Length=710
Score = 47.9 bits (112), Expect = 4e-04, Method: Composition-based stats.
Identities = 20/122 (16%), Positives = 34/122 (28%), Gaps = 11/122 (9%)
Query 513 YLKQAPPSKGPTVRTKKVG-----KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA 567
+++ S P ++ N A L W Q P+ Y + G +
Sbjct 431 FVQMKASSPVPATPILQLEDCCTHNNSATLSWKQPPLSTV--PAEGYILELDDGNGGQFR 488
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
T T+ L ++ Y R+ A+ G T E+
Sbjct 489 EVYVGKETMCTVDGLHFNSTYNARIKAFNKTGVSQYS----KTLVLQTSEVAWFAFDPGS 544
Query 628 AF 629
A
Sbjct 545 AH 546
Score = 46.4 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 19/104 (18%), Positives = 38/104 (37%), Gaps = 8/104 (8%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P P L + + ++ L+W P + +V Y ++ + + ++
Sbjct 441 PATPI-LQLEDCCTHNNSATLSWKQPPLSTVPAEGYILELDDGNGGQFREVY----VGKE 495
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
+ TV L + Y RI+ + G S +S+ T E
Sbjct 496 TMCTVDGLHFNSTYNARIKAFNKTGV---SQYSKTLVLQTSEVA 536
>sp|Q9LHF5|VIL1_ARATH VIN3-like protein 1 OS=Arabidopsis thaliana
OX=3702 GN=VIL1 PE=1 SV=1
Length=602
Score = 47.9 bits (112), Expect = 4e-04, Method: Composition-based stats.
Identities = 19/83 (23%), Positives = 28/83 (34%), Gaps = 2/83 (2%)
Query 225 PHNLSVINSEELSSILKLTW-TNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P + + L PS + Y + Y K + D + T
Sbjct 243 PAACRFHFEDIAPKQVTLRLIELPSAVEYDVKGYKLWYFKKGEMPEDDLFV-DCSRTERR 301
Query 284 FTVQDLKPFTEYVFRIRCMKEDG 306
+ DL+P TEY FR+ E G
Sbjct 302 MVISDLEPCTEYTFRVVSYTEAG 324
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 20/94 (21%), Positives = 36/94 (38%), Gaps = 4/94 (4%)
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-RTIIGNETA 567
+ A + + + + L +LP ++ Y ++Y + E
Sbjct 232 ELSANAGRDLVPAACRFHFEDIAPKQVTLRLIELP-SAVEYDVKGYKLWYFKKGEMPEDD 290
Query 568 VNVDSSHTE--YTLSSLTSDTLYMVRMAAYTDEG 599
+ VD S TE +S L T Y R+ +YT+ G
Sbjct 291 LFVDCSRTERRMVISDLEPCTEYTFRVVSYTEAG 324
>sp|Q05909|PTPRG_MOUSE Receptor-type tyrosine-protein phosphatase
gamma OS=Mus musculus OX=10090 GN=Ptprg PE=1 SV=1
Length=1442
Score = 47.9 bits (112), Expect = 5e-04, Method: Composition-based stats.
Identities = 21/102 (21%), Positives = 40/102 (39%), Gaps = 12/102 (12%)
Query 202 NALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQ 260
N LG S KV +PP ++ V + + L+++W+ P I+ Y I
Sbjct 336 NPLGTEAS---------KVCSSPPIHMKVQPLNQ--TALQVSWSQPETIYHPPIMNYMIS 384
Query 261 YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
Y + + T+ + P + Y+FR++ +
Sbjct 385 YSWTKNEDEKEKTFTKDSDKDLKATISHVSPDSLYLFRVQAV 426
Score = 44.5 bits (103), Expect = 0.006, Method: Composition-based stats.
Identities = 16/80 (20%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV----DSSHT 575
S ++ + + + + W Q P + + I NY I Y +
Sbjct 348 SPPIHMKVQPLNQTALQVSWSQ-PETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDL 406
Query 576 EYTLSSLTSDTLYMVRMAAY 595
+ T+S ++ D+LY+ R+ A
Sbjct 407 KATISHVSPDSLYLFRVQAV 426
Score = 37.5 bits (85), Expect = 0.84, Method: Composition-based stats.
Identities = 12/80 (15%), Positives = 30/80 (38%), Gaps = 6/80 (8%)
Query 425 HPVMDLKAFPKD-NMLWVEWTTP----RESVKKYILEWCVLSDKAPCITDWQQEDGTVHR 479
P + +K P + L V W+ P + Y++ + ++ + ++ +
Sbjct 348 SPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDLK 407
Query 480 TYLRGNLAESKCYLITVTPV 499
+ +++ YL V V
Sbjct 408 ATI-SHVSPDSLYLFRVQAV 426
>sp|Q7Z4K8|TRI46_HUMAN Tripartite motif-containing protein 46
OS=Homo sapiens OX=9606 GN=TRIM46 PE=2 SV=2
Length=759
Score = 47.5 bits (111), Expect = 5e-04, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 36/103 (35%), Gaps = 4/103 (4%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKK--YILEWCV-LSDKAPCITDWQQEDGTVHR 479
PV+D + + +++ W P S Y +E+ P T WQ+ +
Sbjct 430 PEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPGPTRWQRREEVRGT 489
Query 480 TYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSK 521
+ L N Y++ V G G E + + AP
Sbjct 490 SALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLH 532
>sp|P51611|HCFC1_MESAU Host cell factor 1 OS=Mesocricetus auratus
OX=10036 GN=HCFC1 PE=1 SV=1
Length=2090
Score = 47.9 bits (112), Expect = 5e-04, Method: Composition-based stats.
Identities = 29/152 (19%), Positives = 48/152 (32%), Gaps = 27/152 (18%)
Query 478 HRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAP--PSKGPTVRTKKVGKNEA 535
+ + L Y V + A G G I A+ P P ++ K + A
Sbjct 1903 YNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISK-SPDGA 1961
Query 536 VLEWDQLPVDVQNGFIRNYTIF----------------------YRTIIGNETAVNVDSS 573
L W+ P V +G I Y+++ R G + V SS
Sbjct 1962 HLTWE--PPSVTSGKIIEYSVYLAIQSSQAGGEPKSSTPAQLAFMRVYCGPSPSCLVQSS 2019
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
T+ + R+AA ++G +
Sbjct 2020 SLSNAHIDYTTKPAIIFRIAARNEKGYGPATQ 2051
Score = 47.9 bits (112), Expect = 6e-04, Method: Composition-based stats.
Identities = 32/188 (17%), Positives = 56/188 (30%), Gaps = 36/188 (19%)
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
T + Q+L+P T Y FR+ + G+G +S+ S + + P +
Sbjct 1898 GTIPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLP--GFPGAPCAIKIS 1955
Query 336 IDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTV------ 389
P L W+ PP +GKI++Y V L S ++T +
Sbjct 1956 KSPDGAH------LTWE--PPSVTSGKIIEYSVYLAIQSSQAGGEPKSSTPAQLAFMRVY 2007
Query 390 --------------------NLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMD 429
T + + RN G A + + +
Sbjct 2008 CGPSPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSKDSSGTKP 2067
Query 430 LKAFPKDN 437
P +
Sbjct 2068 ASKRPMSS 2075
Score = 41.4 bits (95), Expect = 0.048, Method: Composition-based stats.
Identities = 35/167 (21%), Positives = 53/167 (32%), Gaps = 29/167 (17%)
Query 192 VNIEVWVEAENALGKVTSDHIN-FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+ V NA G+ I+ F P P + + S + + LTW PS+
Sbjct 1915 TAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPDGA---HLTWEPPSVT 1971
Query 251 SVIILKYNIQY---------RTKDASTWSQIPPEDTASTRSSFTVQ--DL-KPFTEYV-- 296
S I++Y++ K ++ S VQ L +Y
Sbjct 1972 SGKIIEYSVYLAIQSSQAGGEPKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTK 2031
Query 297 ----FRIRCMKEDGKGYWSD--WSEEAS-----GITYEDRPSKAPSF 332
FRI E G G + W +E S RP +P
Sbjct 2032 PAIIFRIAARNEKGYGPATQVRWLQETSKDSSGTKPASKRPMSSPEM 2078
Score = 38.7 bits (88), Expect = 0.33, Method: Composition-based stats.
Identities = 30/244 (12%), Positives = 63/244 (26%), Gaps = 51/244 (21%)
Query 303 KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEA--- 359
E G S + P K + W+ + +V + LPP +A
Sbjct 1837 TEVDNGIESLGVKPDLPPPPSKAPVKKENQWFDV---GVIKGTSVMVTHYFLPPDDAVQS 1893
Query 360 ---NGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI 416
+G I DY K LQ Y + N G+ + ++
Sbjct 1894 DDDSGTIPDYN---QLKKQELQ-------------PGTAYKFRVAGINACGRGPFSEISA 1937
Query 417 PACDFQATH-PVMDLKAFPKDNMLWVEWTTPR---ESVKKYILEWCVLSDKAPCITDWQQ 472
+K + + W P + +Y + + S +A
Sbjct 1938 FKTCLPGFPGAPCAIKISKSPDGAHLTWEPPSVTSGKIIEYSVYLAIQSSQAGGEPKSST 1997
Query 473 -------------------EDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAY 513
+ ++ ++ + + G G ++ +
Sbjct 1998 PAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAII--FRIAARNEKGYGPATQVR-W 2054
Query 514 LKQA 517
L++
Sbjct 2055 LQET 2058
>sp|A0A0G2JXN2|TRI46_RAT Tripartite motif-containing protein 46
OS=Rattus norvegicus OX=10116 GN=Trim46 PE=1 SV=2
Length=759
Score = 47.5 bits (111), Expect = 5e-04, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 36/103 (35%), Gaps = 4/103 (4%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKK--YILEWCV-LSDKAPCITDWQQEDGTVHR 479
PV+D + + +++ W P S Y +E+ P T WQ+ +
Sbjct 430 PEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPGPTRWQRREEVRGT 489
Query 480 TYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSK 521
+ L N Y++ V G G E + + AP
Sbjct 490 SALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLH 532
>sp|P03749|TIPJ_LAMBD Tip attachment protein J OS=Escherichia
phage lambda OX=2681611 GN=J PE=1 SV=1
Length=1132
Score = 47.5 bits (111), Expect = 6e-04, Method: Composition-based stats.
Identities = 44/276 (16%), Positives = 91/276 (33%), Gaps = 28/276 (10%)
Query 50 LKEKCMDYFHVNANYIVWKTNHFTIPKEQYTII------NRTASSVTFTDIASLNIQLTC 103
+K K A Y VW+ T+ + + + + T + + +
Sbjct 542 VKVKVSRVPDGVAEYSVWELKLPTLRQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDN 601
Query 104 NILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGK---KMRCEWDGGRETHLETNFTL 160
G+ V G+T PP ++L+ V ++ WD + +F L
Sbjct 602 GAHFDGEQSGTVNGVT-----PPAV-QHLTAEVTADSGEYQVLARWDTPKV-VKGVSFLL 654
Query 161 KSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK-VTSDHINFDPVYK 219
+ ++ T T ++ + N + V A NA G+ ++F
Sbjct 655 RLTVTADDGSERLVSTARTTETTYRFTQLALGNYRLTVRAVNAWGQQGDPASVSFR---I 711
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
P P + E ++T T +++ + K + Q+
Sbjct 712 AAPAAPSRI-----ELTPGYFQITATPHLAVYDPTVQFEFWFSEKQIADIRQVETSTRYL 766
Query 280 TRSSFTV---QDLKPFTEYVFRIRCMKEDGKGYWSD 312
+ + + ++KP +Y F IR + GK + +
Sbjct 767 GTALYWIAASINIKPGHDYYFYIRSVNTVGKSAFVE 802
>sp|Q9UHF4|I20RA_HUMAN Interleukin-20 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL20RA PE=1 SV=2
Length=553
Score = 47.5 bits (111), Expect = 6e-04, Method: Composition-based stats.
Identities = 34/194 (18%), Positives = 55/194 (28%), Gaps = 15/194 (8%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P N++ ++ + L WT P + + Y +QY W +
Sbjct 40 PANITFLSINMKN---VLQWTPPEGLQGVKVTYTVQYFIYGQKKWLNKSECRNINRTY-- 94
Query 285 TVQDLKPFTE-YVFRIRCMKEDGKG-YWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
DL T Y + + G S W+E + + P D
Sbjct 95 --CDLSAETSDYEHQYYAKVKAIWGTKCSKWAESGRFYPFLETQIGPPEVALTTDEKSIS 152
Query 343 GYRTVQLVWKTLPPFEANG-----KILDYEVTLTRWKSH-LQNYTVNATKLTVNLTNDRY 396
T WK P L Y V++ KS+ + V L +
Sbjct 153 VVLTAPEKWKRNPEDLPVSMQQIYSNLKYNVSVLNTKSNRTWSQCVTNHTLVLTWLEPNT 212
Query 397 LATLTVRNLVGKSD 410
L + V + V
Sbjct 213 LYCVHVESFVPGPP 226
Score = 38.7 bits (88), Expect = 0.28, Method: Composition-based stats.
Identities = 60/407 (15%), Positives = 121/407 (30%), Gaps = 60/407 (15%)
Query 119 TIISGLPPEKPKNLSCIVNEGKKMRCEWDGGR-ETHLETNFTLKSEWATHKFADCKAKRD 177
+ GLP KP N++ + K + +W ++ +T++ K K++
Sbjct 32 CVSGGLP--KPANITFLSINMKNV-LQWTPPEGLQGVKVTYTVQYFIYGQKKWLNKSECR 88
Query 178 TPTSCTVDY---STVYFVNIEVWVEAE--NALGKVTSDHINFDPVYKVKPNPPHNLSVIN 232
D ++ Y V+A K F P + + PP +
Sbjct 89 NINRTYCDLSAETSDYEHQYYAKVKAIWGTKCSKWAESGR-FYPFLETQIGPPEVALTTD 147
Query 233 SEELSSILKL--TWT-NPSIKSV------IILKYNIQ-YRTKDASTWSQIPPEDTASTRS 282
+ +S +L W NP V LKYN+ TK TWSQ T
Sbjct 148 EKSISVVLTAPEKWKRNPEDLPVSMQQIYSNLKYNVSVLNTKSNRTWSQCVTNHT----- 202
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
+ L+P T Y + G + SE+ T +D +
Sbjct 203 -LVLTWLEPNTLYCVHVESFVP-GPPRRAQPSEKQCARTLKD---------------QSS 245
Query 343 GYRTVQLVWK--TLPPFEANGKILDYEVT----LTRWKSHLQNYTVNATKL--TVNLTND 394
++ + W + ++ Y + + + K + + + +
Sbjct 246 EFKAKIIFWYVLPVSITVFLFSVMGYSIYRYIHVGKEKHPANLILIYGNEFDKRFFVPAE 305
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYI 454
+ + N+ S + + + ++ P N+ P+E +
Sbjct 306 KIVINFITLNISDDSKISHQDMSLLGKSSDVSSLN-DPQPSGNL-----RPPQEEEEVKH 359
Query 455 LEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAES----KCYLITVT 497
L + + C ++ E ++ + Y V
Sbjct 360 LGYASHLMEIFCDSEENTEGTSLTQQESLSRTIPPDKTVIEYEYDVR 406
>sp|Q7TNM2|TRI46_MOUSE Tripartite motif-containing protein 46
OS=Mus musculus OX=10090 GN=Trim46 PE=1 SV=1
Length=759
Score = 47.5 bits (111), Expect = 6e-04, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 36/103 (35%), Gaps = 4/103 (4%)
Query 423 ATHPVMDLKAFPKDNMLWVEWTTPRESVKK--YILEWCV-LSDKAPCITDWQQEDGTVHR 479
PV+D + + +++ W P S Y +E+ P T WQ+ +
Sbjct 430 PEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPGPTRWQRREEVRGT 489
Query 480 TYLRGNLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPPSK 521
+ L N Y++ V G G E + + AP
Sbjct 490 SALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLH 532
>sp|P18475|TORSO_DROME Tyrosine-protein kinase receptor torso
OS=Drosophila melanogaster OX=7227 GN=tor PE=1 SV=2
Length=923
Score = 47.5 bits (111), Expect = 6e-04, Method: Composition-based stats.
Identities = 69/385 (18%), Positives = 118/385 (31%), Gaps = 70/385 (18%)
Query 294 EYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKT 353
Y + C E + DW + + G AP+ Y I +
Sbjct 76 NYQMNMICRTESEIVFQIDWVQHSRGT------EPAPNATYIIRVDAVKDDNKET----A 125
Query 354 LPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAV 413
L + N IL N T N T L ++ +L ++
Sbjct 126 LYLSDDNFLIL---------PGLESNSTHNITALAMHGDGS---YSLIAKDQTFA----- 168
Query 414 LTIPACDFQATHPVMDLKAFPKDNML-----WVEWTTPRESVKKY-ILEWCVLSDKAPCI 467
I V L+ P+ + L +EW ES + ++ + S
Sbjct 169 TLIRGYQPSKMGAVNLLRFVPQPDDLHHIAAEIEWKPSAESNCYFDMVSYSTNSVNMDEP 228
Query 468 TDWQQEDGTVHRTYLRGNLAESKCYLITVTPVY------ADGPGSPESIKAYLKQ----- 516
+ Q D + NL K Y + V V +D P ++ + L
Sbjct 229 LEVQFRDRKKLYRHTVDNLEFDKQYHVGVRTVNIMNRLESDLQWLPIAVPSCLDWYPYNY 288
Query 517 --APPSKGPTVRT--KKVGKN--EAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN- 569
PP K + K+ N + W + N YT+ + T +N
Sbjct 289 TLCPPHKPENLTVTQKQYLPNILALNITWARPRYLPDN-----YTLHIFDLFKGGTELNY 343
Query 570 -VDSSHTEYTLSSLTS-DTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQG--------EIE 619
+D + + + + +T + + V + A GGK+ T +
Sbjct 344 TLDQNRSHFYVPKITVLGSHFEVHLVAQ-SAGGKNVSGLTLDKVHRGVLLSEGNMVKLVL 402
Query 620 AIVVPVCLAFLLTTLLGVLFCFNKR 644
I+VP+C +L +L FC R
Sbjct 403 FIIVPICCILMLCSLT---FCRRNR 424
>sp|A0P8X0|AAMY_NIACI Alpha-amylase OS=Niallia circulans OX=1397
GN=igtZ PE=1 SV=1
Length=1290
Score = 47.2 bits (110), Expect = 8e-04, Method: Composition-based stats.
Identities = 50/304 (16%), Positives = 90/304 (30%), Gaps = 43/304 (14%)
Query 324 DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYE-----VTLTRWKSHLQ 378
+ PS W+ + G V E + Y T S +
Sbjct 606 AKDKTGPSVWWPQRYPYNPGSANV-------SKAEG-WTLQHYNNAFAIYTYAFDTSGIS 657
Query 379 NYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTI-PACDFQATHPVMDLKAFPKDN 437
V + + T D T V + G + A + I PA T M+++ D
Sbjct 658 EIKVKV-RAHRDKTADAADNTFKVYDPAGLAAAGIANIDPAKVGAWTEYPMNVRDLSAD- 715
Query 438 MLWVEWTT---------PRESVKKYILEWCVLSDKAPCITDWQQED--GTVHRTYLRGNL 486
+ V+W P + + + +D G V ++ ++
Sbjct 716 INGVDWQPSSMTIMQKVPATDIGNLYFSYISDYRDQLLDYFIEAKDAKGNVTQSDIQQVY 775
Query 487 AESKCYLITVTPVYADGPGSPESIKAYLKQAP-------PSKGPTVRTKKVGKNEAVLEW 539
+ Y + G+ E ++ P P+ ++ + + L W
Sbjct 776 VGAGKYKLANGKYTESMQGTIEGTHPFITDVPAVPDTEAPAVPANLQATVMNASSVGLSW 835
Query 540 DQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEG 599
+ N + Y I+ + T YT S L++ T Y R+ AY G
Sbjct 836 N---AATDNIRVTGYEIY------RNGVRIGTTPSTSYTDSGLSASTAYEYRVKAYDASG 886
Query 600 GKDG 603
G
Sbjct 887 NLSG 890
Score = 40.6 bits (93), Expect = 0.090, Method: Composition-based stats.
Identities = 18/91 (20%), Positives = 31/91 (34%), Gaps = 13/91 (14%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPE 275
P P NL +S + L+W + ++ + Y I YR
Sbjct 809 VPDTEAPAVPANLQATVMN--ASSVGLSWNAATD-NIRVTGYEI-YRN---------GVR 855
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ +S+T L T Y +R++ G
Sbjct 856 IGTTPSTSYTDSGLSASTAYEYRVKAYDASG 886
>sp|A0A140LHF2|VSXL2_MOUSE V-set and immunoglobulin domain-containing
protein 10-like 2 OS=Mus musculus OX=10090 GN=Vsig10l2
PE=3 SV=2
Length=776
Score = 46.8 bits (109), Expect = 0.001, Method: Composition-based stats.
Identities = 27/132 (20%), Positives = 46/132 (35%), Gaps = 19/132 (14%)
Query 200 AENALGKVTSDHINFDPVYK--------VKPNPPHNLSVINSE--ELSSILKLTWTNPSI 249
A NALG +S + + + + P PP N+++ ++L W
Sbjct 578 ARNALGN-SSQSVLLEVLSECKGFVCPCGYPTPP-NVTISRLTYRRQRREVQLQWA--IY 633
Query 250 KSVIILKYNIQYR----TKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKED 305
+ + +Q R + +A W ++ D + L P Y FRI M
Sbjct 634 GPGNLTGFLVQQRASVPSSEAGAW-EVAASDIEPESRDRRLGGLDPGVLYAFRILAMNHH 692
Query 306 GKGYWSDWSEEA 317
GY S+
Sbjct 693 TAGYPSEVKTPV 704
Score = 38.7 bits (88), Expect = 0.27, Method: Composition-based stats.
Identities = 29/219 (13%), Positives = 59/219 (27%), Gaps = 32/219 (15%)
Query 341 TQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL 400
+G QL+W + G + + +HL+ +A + + R
Sbjct 524 QRGTPPAQLLWLGPQQQQLEGSTPGFILH--PEGTHLRLQVRDA-----DPAHHRGTYQC 576
Query 401 TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVL 460
RN +G S +VL + + +P + + T R ++ L+W +
Sbjct 577 VARNALGNSSQSVLLEVLSECKGFVCPC---GYPTPPNVTISRLTYRRQRREVQLQWAIY 633
Query 461 SDK--------------APCITDWQQEDGTVH---RTYLRGNLAESKCYLITVTPVYADG 503
+ W+ + R G L Y + +
Sbjct 634 GPGNLTGFLVQQRASVPSSEAGAWEVAASDIEPESRDRRLGGLDPGVLYAFRILAMNHHT 693
Query 504 PGSPESIKAYLKQA-----PPSKGPTVRTKKVGKNEAVL 537
G P +K + A ++
Sbjct 694 AGYPSEVKTPVDPAFSAYPAVLGAAGTGVVVALATSLLV 732
Score = 37.5 bits (85), Expect = 0.72, Method: Composition-based stats.
Identities = 21/141 (15%), Positives = 38/141 (27%), Gaps = 17/141 (12%)
Query 522 GPTVRTKKVG----KNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA-------VNV 570
P V ++ + E L+W G + + + R + + A ++
Sbjct 609 PPNVTISRLTYRRQRREVQLQWAIYGP----GNLTGFLVQQRASVPSSEAGAWEVAASDI 664
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFL 630
+ + L L LY R+ A G TP V+ +
Sbjct 665 EPESRDRRLGGLDPGVLYAFRILAMNH--HTAGYPSEVKTPVDPAFSAYPAVLGAAGTGV 722
Query 631 LTTLLGVLFCFNKRDLIKKHI 651
+ L L F
Sbjct 723 VVALATSLLVFQYAARHPHTF 743
>sp|F1QPX0|NDNF_DANRE Protein NDNF OS=Danio rerio OX=7955 GN=ndnf
PE=3 SV=2
Length=574
Score = 46.4 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 34/184 (18%), Positives = 53/184 (29%), Gaps = 24/184 (13%)
Query 318 SGITYE-DRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH 376
S T E D+P + ++D + G TV L WK P G+ + Y V + +
Sbjct 163 STTTPESDQPYPELPYDPRVDVTA-LGRTTVTLAWKPTPTGSVMGQPIQYCVVINKEH-- 219
Query 377 LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD 436
N+ +D ++ DF V F KD
Sbjct 220 --NFKSLCAAEAKMSLDDAFMIA----------PKPGRDFSPFDFAYFGFVPSENDFHKD 267
Query 437 NMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITV 496
L + + YI P + D Q+ + +L Y V
Sbjct 268 RFLTTNRALSNKMSRAYI--------PKPKVADIQKICIGNKNIFTITDLKPDTQYYFDV 319
Query 497 TPVY 500
V
Sbjct 320 FAVN 323
>sp|Q3SXY7|LRIT3_HUMAN Leucine-rich repeat, immunoglobulin-like
domain and transmembrane domain-containing protein 3 OS=Homo
sapiens OX=9606 GN=LRIT3 PE=1 SV=3
Length=679
Score = 46.0 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 28/155 (18%), Positives = 51/155 (33%), Gaps = 16/155 (10%)
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV-NVDSSHTEYTLSSL 582
+R K L W+ + + T+ Y G + + N DSS + T+ L
Sbjct 489 NLRVVSETKESVTLTWNMINTTHNSAV----TVLYSKYGGKDLLLLNADSSKNQVTIDGL 544
Query 583 TSDTLYMVRMAAYTDEGGKDGPE--FTFTT--PKFAQGEIEAIVVPVCLAFLLTTLLGVL 638
YM + G + TF+T + + ++V A ++ L
Sbjct 545 EPGGQYMACVCPK---GVPPQKDQCITFSTERVEGDDSQWSLLLVVTSTACVVILPLICF 601
Query 639 FCFN--KRDLIKKHIWPNVPDPSKSHIAQWSPHTP 671
+ K + W + D +K Q+ P
Sbjct 602 LLYKVCKLQCKSEPFWED--DLAKETYIQFETLFP 634
>sp|A6NNM3|RIM3B_HUMAN RIMS-binding protein 3B OS=Homo sapiens
OX=9606 GN=RIMBP3B PE=3 SV=3
Length=1639
Score = 46.4 bits (108), Expect = 0.002, Method: Composition-based stats.
Identities = 36/209 (17%), Positives = 66/209 (32%), Gaps = 27/209 (13%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P L + N S+ + +++ V+ L T + S
Sbjct 994 MAPMQLHLQNVTATSANITWVYSSHRHPHVVYLD--------------DREHALTPAGVS 1039
Query 283 SFTVQDLKPFTEYVFRIRCMK--EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
+T Q L P T Y R+ + + YW S + T P P ++
Sbjct 1040 CYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPP---LEVLVER 1096
Query 341 TQGYRTVQLVWKTL---PPFEANG-KILDYEVTLTRWKS-HLQNYTVNATKLTV---NLT 392
+ + W + +NG ++ Y V K + + T +T L +
Sbjct 1097 HASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVP 1156
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDF 421
++ +L G+S +V DF
Sbjct 1157 LTWQKVSVRTMSLCGESLDSVPAQIPEDF 1185
>sp|A6NJZ7|RIM3C_HUMAN RIMS-binding protein 3C OS=Homo sapiens
OX=9606 GN=RIMBP3C PE=1 SV=3
Length=1639
Score = 46.0 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 36/209 (17%), Positives = 65/209 (31%), Gaps = 27/209 (13%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P L + N S+ + +++ V+ L T + S
Sbjct 994 MAPMQLHLQNVTATSANITWVYSSHRHPHVVYLD--------------DREHALTPAGVS 1039
Query 283 SFTVQDLKPFTEYVFRIRCMK--EDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
+T Q L P T Y R+ + + YW S + T P P +
Sbjct 1040 CYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPP---LDVLVER 1096
Query 341 TQGYRTVQLVWKTL---PPFEANG-KILDYEVTLTRWKS-HLQNYTVNATKLTV---NLT 392
+ + W + +NG ++ Y V K + + T +T L +
Sbjct 1097 HASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVP 1156
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDF 421
++ +L G+S +V DF
Sbjct 1157 LTWQKVSVRTMSLCGESLDSVPAQIPEDF 1185
>sp|Q1ENI8|PXDN1_CAEEL Peroxidasin homolog pxn-1 OS=Caenorhabditis
elegans OX=6239 GN=pxn-1 PE=1 SV=1
Length=1285
Score = 46.0 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 32/196 (16%), Positives = 62/196 (32%), Gaps = 43/196 (22%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTI---PKEQYTIINRTASSV 89
P + S C + I W N K Q + N
Sbjct 321 PRDNSFREGSEVKVNCEVMGN-------PKPTINWYHNGKRFISSRKRQLGLSNNVLRIY 373
Query 90 TFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPP---EKPKNLSCIVNEGKKMRC-- 144
F + + + TC + ++ + + +IS +PP E P+++S + C
Sbjct 374 PF--LEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVCKA 431
Query 145 --------EW--DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNI 194
W DG H++ F + + + ++ + K + SC
Sbjct 432 NGNPVPDYTWSFDGSTIGHIKGRFMVSDDGTELRISNIEKKDEGYYSC------------ 479
Query 195 EVWVEAENALGKVTSD 210
A N +G +++D
Sbjct 480 ----MAGNPVGAMSAD 491
>sp|Q6PHB0|I20RA_MOUSE Interleukin-20 receptor subunit alpha OS=Mus
musculus OX=10090 GN=Il20ra PE=2 SV=2
Length=546
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 55/299 (18%), Positives = 98/299 (33%), Gaps = 38/299 (13%)
Query 119 TIISGLPPEKPKNLSCIVNEGKKMRCEWDGG-RETHLETNFTLKSEWATHKFADCKAKRD 177
+ GLP KP N++ + K + W+ +E +T++ K +K
Sbjct 35 CVFCGLP--KPTNITFLSINMKNV-LHWNPPESLHGVEVTYTVQYFIYGQKKWLNASKCG 91
Query 178 TPTSCTVDY---STVYFVNIEVWVEAENALG-KVTSDHINFDPVYKVKPNPPHNLSVINS 233
+ D ++ Y V+A ++ F P + + +PP + +
Sbjct 92 SINRTYCDLSVETSDYEHQFYAKVKAIWEARCSEWAETERFYPFLETQVSPPE--VALTT 149
Query 234 EELSSILKLT----WTNPSIKS-------VIILKYNIQ-YRTKDASTWSQIPPEDTASTR 281
E S + LT W LKYN+ Y TK TWSQ T
Sbjct 150 GEKSISIALTAPEKWKRNPQDHTVSMQQIYPNLKYNVSVYNTKSRRTWSQ------CVTN 203
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHT 341
S+ + L+P T Y + + G S++ T E + S W
Sbjct 204 STLVLSWLEPNTLYCVHVESLVP-GPPRLPMPSQKQCISTLEVQTS----AWKAKVIFWY 258
Query 342 QGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATL 400
+V + F A G ++ + + + K + ++ + TL
Sbjct 259 VFLTSVIVF-----LFSAIGYLVYRYIHVGKEKHPANLVLIYRNEIGTRVFEPTETITL 312
Score = 42.9 bits (99), Expect = 0.015, Method: Composition-based stats.
Identities = 33/194 (17%), Positives = 57/194 (29%), Gaps = 15/194 (8%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P N++ ++ + L W P + + Y +QY W + +
Sbjct 43 PTNITFLSINMKN---VLHWNPPESLHGVEVTYTVQYFIYGQKKWLNASKCGSINRTY-- 97
Query 285 TVQDLKPFTE-YVFRIRCM-KEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQ 342
DL T Y + K + S+W+E + + P
Sbjct 98 --CDLSVETSDYEHQFYAKVKAIWEARCSEWAETERFYPFLETQVSPPEVALTTGEKSIS 155
Query 343 GYRTVQLVWKTLPPFEANG-----KILDYEVTLTRWKS-HLQNYTVNATKLTVNLTNDRY 396
T WK P L Y V++ KS + V + L ++
Sbjct 156 IALTAPEKWKRNPQDHTVSMQQIYPNLKYNVSVYNTKSRRTWSQCVTNSTLVLSWLEPNT 215
Query 397 LATLTVRNLVGKSD 410
L + V +LV
Sbjct 216 LYCVHVESLVPGPP 229
>sp|Q8TC84|FANK1_HUMAN Fibronectin type 3 and ankyrin repeat domains
protein 1 OS=Homo sapiens OX=9606 GN=FANK1 PE=1 SV=3
Length=345
Score = 44.8 bits (104), Expect = 0.002, Method: Composition-based stats.
Identities = 21/113 (19%), Positives = 34/113 (30%), Gaps = 7/113 (6%)
Query 518 PPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRN-YTIFYRTIIG--NETAVNVDSSH 574
PPSK KV + L WD + G + + +
Sbjct 8 PPSKPHPPVVGKVTHHSIELYWDLEKKAKRQGPQEQWFRFSIEEEDPKMHTYGIIYTGYA 67
Query 575 TEYTLSSLTSDTLYMVRMAAYTDEG----GKDGPEFTFTTPKFAQGEIEAIVV 623
T++ + L TLY R+ + G T P ++ A+ V
Sbjct 68 TKHVVEGLEPRTLYRFRLKVTSPSGECEYSPLVSVSTTREPISSEHLHRAVSV 120
Score = 41.8 bits (96), Expect = 0.022, Method: Composition-based stats.
Identities = 19/112 (17%), Positives = 38/112 (34%), Gaps = 6/112 (5%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN-IQYRTKDASTWSQIP 273
+P + P+ PH V S ++L W + ++ ++
Sbjct 2 EPQKIMPPSKPHPPVVGKVTHHS--IELYWDLEKKAKRQGPQEQWFRFSIEEEDPKMHTY 59
Query 274 PEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDR 325
+ V+ L+P T Y FR++ G+ ++S S T +
Sbjct 60 GIIYTGYATKHVVEGLEPRTLYRFRLKVTSPSGE---CEYSPLVSVSTTREP 108
>sp|A0A8G1A3Q5|CHI52_PAEXY Chitinase Chi52 OS=Paenibacillus xylanexedens
OX=528191 GN=Chi52 PE=1 SV=1
Length=523
Score = 45.2 bits (105), Expect = 0.002, Method: Composition-based stats.
Identities = 40/262 (15%), Positives = 80/262 (31%), Gaps = 33/262 (13%)
Query 499 VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY 558
+G G APPS + + + L W+ N + Y ++
Sbjct 76 YVGEGSGGETPTPDT---APPSVPAGLTSSSITDTSVSLSWN---ASTDNVGVAGYEVY- 128
Query 559 RTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT-TPKFAQGE 617
+ +S T ++ LT+ T Y + A G + + T
Sbjct 129 -----RNGVLVTSTSTTTAVVTGLTASTTYAFTVKAKDAAGNISAASTSLSVTTSNGSSN 183
Query 618 IEAIVVPVCLAFL-----LTTLLGVLFCFNKRDLIKKHIWPNVPD--------PSKSHIA 664
+ + +T + + D+I + P + +A
Sbjct 184 PGPTGTKWLIGYWHNFDNGSTNIRLRNVSTAYDVINVSFAEPISHGSGTLAFTPYNATVA 243
Query 665 QWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDL---FKKEKINT 721
++ + K + G + + +A ++ F + LKS+ F I+
Sbjct 244 EFKSDIAYLQSQGKKVLLSMGGANGTIELT--DATKRQQFEDSLKSIISTYGFNGLDIDL 301
Query 722 EGHSSGI--GGSSCMSSSRPSI 741
EG S + G + S + P I
Sbjct 302 EGSSLSLNAGDTDFRSPTTPKI 323
Score = 38.3 bits (87), Expect = 0.39, Method: Composition-based stats.
Identities = 22/113 (19%), Positives = 40/113 (35%), Gaps = 15/113 (13%)
Query 218 YKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
P+ P L+ +S + + L+W + +V + Y + YR T
Sbjct 89 DTAPPSVPAGLT--SSSITDTSVSLSWNASTD-NVGVAGYEV-YRNGVLVT--------- 135
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 330
+++ ++ V L T Y F ++ G S S S T + P
Sbjct 136 STSTTTAVVTGLTASTTYAFTVKAKDAA--GNISAASTSLSVTTSNGSSNPGP 186
Score = 37.1 bits (84), Expect = 0.80, Method: Composition-based stats.
Identities = 22/124 (18%), Positives = 40/124 (32%), Gaps = 9/124 (7%)
Query 310 WSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVT 369
W E + G T P AP S + +V L W N + YEV
Sbjct 74 WKYVGEGSGGETP--TPDTAPPSVPAGLTSSSITDTSVSLSWNA---STDNVGVAGYEVY 128
Query 370 LTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVG--KSDAAVLTIPACDFQATHPV 427
R + + + +T + Y T+ ++ G + + L++ + +
Sbjct 129 --RNGVLVTSTSTTTAVVTGLTASTTYAFTVKAKDAAGNISAASTSLSVTTSNGSSNPGP 186
Query 428 MDLK 431
K
Sbjct 187 TGTK 190
Score = 33.7 bits (75), Expect = 9.5, Method: Composition-based stats.
Identities = 21/121 (17%), Positives = 36/121 (30%), Gaps = 12/121 (10%)
Query 406 VGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAP 465
VG+ P + P + D + + W ++V + + V +
Sbjct 77 VGEGSGGETPTP-DTAPPSVPAGLTSSSITDTSVSLSWNASTDNVG--VAGYEVYRNGVL 133
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGP--GSPESIKAYLKQAPPSKGP 523
+ T T + L S Y TV A G + S+ + GP
Sbjct 134 VTS-------TSTTTAVVTGLTASTTYAFTVKAKDAAGNISAASTSLSVTTSNGSSNPGP 186
Query 524 T 524
T
Sbjct 187 T 187
>sp|Q8XL08|OGA_CLOPE O-GlcNAcase NagJ OS=Clostridium perfringens
(strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1
Length=1001
Score = 45.6 bits (106), Expect = 0.003, Method: Composition-based stats.
Identities = 18/102 (18%), Positives = 35/102 (34%), Gaps = 8/102 (8%)
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
I+ + + + ++ K + W + + G + Y ++ G +
Sbjct 905 IEGTSPEIVVNPVRDFKASEINKKNVTVTWTE--PETTEG-LEGYILY---KDGKKV-AE 957
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF-TFTT 610
+ T YT L T+Y ++AA G E T T
Sbjct 958 IGKDETSYTFKKLNRHTIYNFKIAAKYSNGEVSSKESLTLRT 999
>sp|Q0TR53|OGA_CLOP1 O-GlcNAcase NagJ OS=Clostridium perfringens
(strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC
8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1
Length=1001
Score = 45.6 bits (106), Expect = 0.003, Method: Composition-based stats.
Identities = 18/102 (18%), Positives = 35/102 (34%), Gaps = 8/102 (8%)
Query 510 IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVN 569
I+ + + + ++ K + W + + G + Y ++ G +
Sbjct 905 IEGTSPEIVVNPVRDFKASEINKKNVTVTWTE--PETTEG-LEGYILY---KDGKKV-AE 957
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEF-TFTT 610
+ T YT L T+Y ++AA G E T T
Sbjct 958 IGKDETSYTFKKLNRHTIYNFKIAAKYSNGEVSSKESLTLRT 999
>sp|Q2YDH8|FNDC8_BOVIN Fibronectin type III domain-containing
protein 8 OS=Bos taurus OX=9913 GN=FNDC8 PE=2 SV=1
Length=321
Score = 44.8 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 30/167 (18%), Positives = 55/167 (33%), Gaps = 8/167 (5%)
Query 206 KVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT-NPSIKSV----IILKYNIQ 260
+V +D + V + P V S ++WT P + V ++L+ ++
Sbjct 157 EVDTDTSSTPSESSVVLDVPEAPFVCEHTVSDSTAVISWTYAPGKQQVSFYQVLLQEVVR 216
Query 261 YRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
+ + P ++ + +LKP T Y +R G G W + A+
Sbjct 217 KNSGETPKAKNRPWIFNKILGTTVKLMELKPNTSYCLTVRAANTAGVGTWCKPYKFATVA 276
Query 321 T-YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
T P P +TV L + + E + Y
Sbjct 277 TDLNSFPENNP--IQITVQRKEPQRKTVSLGLEDMRRLEDLEHLFPY 321
Score = 39.8 bits (91), Expect = 0.10, Method: Composition-based stats.
Identities = 16/93 (17%), Positives = 30/93 (32%), Gaps = 13/93 (14%)
Query 519 PSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYT 578
+ P V V + AV+ W P Q F Y + + ++ + + + +
Sbjct 175 VPEAPFVCEHTVSDSTAVISWTYAPGKQQVSF---YQVLLQEVVRKNSGETPKAKNRPWI 231
Query 579 ----------LSSLTSDTLYMVRMAAYTDEGGK 601
L L +T Y + + A G
Sbjct 232 FNKILGTTVKLMELKPNTSYCLTVRAANTAGVG 264
>sp|P0DP72|VSXL2_HUMAN V-set and immunoglobulin domain-containing
protein 10-like 2 OS=Homo sapiens OX=9606 GN=VSIG10L2 PE=3
SV=1
Length=767
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 22/119 (18%), Positives = 41/119 (34%), Gaps = 13/119 (11%)
Query 200 AENALGKVTSDHINFDPVYKVKPNPPHNLSVIN--SEELSSILKLTWTNPSIKSVIILKY 257
A NA+G + + P PP N+++ ++L W + + +
Sbjct 579 ARNAVGNSS---QSVLLEVLRYPAPP-NVTISRLTYGRHRREVQLQWA--ILGPGNLTGF 632
Query 258 NIQYRT----KDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
+Q + A W + +R + L P Y FRI + G+ S+
Sbjct 633 LVQRKASALGPGAGAWETAASDIEPESRGR-RLGGLDPGVLYAFRILALNHHTAGHPSE 690
Score = 43.3 bits (100), Expect = 0.011, Method: Composition-based stats.
Identities = 21/134 (16%), Positives = 40/134 (30%), Gaps = 12/134 (9%)
Query 395 RYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFP-KDNMLWVEWT-TPRESVKK 452
R RN VG S +VL + + + + ++W ++
Sbjct 572 RGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGRHRREVQLQWAILGPGNLTG 631
Query 453 YILEWCVLSDKAPCITDWQQEDGTVH---RTYLRGNLAESKCYLITVTPVYADGPGSPES 509
++++ S P W+ + R G L Y + + G P
Sbjct 632 FLVQ-RKASALGPGAGAWETAASDIEPESRGRRLGGLDPGVLYAFRILALNHHTAGHPSE 690
Query 510 IKAYLKQAPPSKGP 523
+K P+ P
Sbjct 691 VKI------PADPP 698
>sp|P12625|PHB_RALPI Poly(3-hydroxybutyrate) depolymerase OS=Ralstonia
pickettii OX=329 PE=3 SV=1
Length=488
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 27/169 (16%), Positives = 48/169 (28%), Gaps = 26/169 (15%)
Query 355 PPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLT---VRNLVGKSDA 411
P ++NGK+ +E++++ T V+ T+ Y + V+N +
Sbjct 280 PYTDSNGKVRTHEISVSGMAHAWPAGTGGDNTNYVDATHINYPVFVMDYWVKNNLRAGSG 339
Query 412 AVLTIPACDFQATHPVMDLKAFPK-DNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDW 470
QA L + + W + + + S
Sbjct 340 T--------GQAGSAPTGLAVTATTSTSVSLSWNAVANASSYGV--YRNGS--------- 380
Query 471 QQEDGTVHRTYLRGNLAESKCYLITVTPV--YADGPGSPESIKAYLKQA 517
+ Y L Y TVT V A ++ A K A
Sbjct 381 -KVGSATATAYTDSGLIAGTTYSYTVTAVDPTAGESQPSAAVSATTKSA 428
>sp|Q9NQ86|TRI36_HUMAN E3 ubiquitin-protein ligase TRIM36 OS=Homo
sapiens OX=9606 GN=TRIM36 PE=1 SV=2
Length=728
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 15/96 (16%), Positives = 29/96 (30%), Gaps = 5/96 (5%)
Query 426 PVMDLKAFPKDNMLWVEWTTPRESVKK-YILEWCVLSDKAPCITDWQQEDGTVHRTYLRG 484
P ++ + N + W P + Y+LE+ ++ W E + +
Sbjct 420 PEINEEQSKVYNNALINWHHPEKDKADSYVLEYRKINRDDE--MSW-NEIEVCGTSKIIQ 476
Query 485 NLAESKCYLITVTPVYADGPGS-PESIKAYLKQAPP 519
+L S Y V + + AP
Sbjct 477 DLENSSTYAFRVRAYKGSICSPCSRELILHTPPAPV 512
Score = 43.7 bits (101), Expect = 0.008, Method: Composition-based stats.
Identities = 16/80 (20%), Positives = 27/80 (34%), Gaps = 3/80 (4%)
Query 533 NEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
N A++ W D + ++ Y R + + V T + L + + Y R+
Sbjct 431 NNALINWHHPEKDKADSYVLEYRKINRDDEMSWNEIEVCG--TSKIIQDLENSSTYAFRV 488
Query 593 AAYTDEGGKD-GPEFTFTTP 611
AY E TP
Sbjct 489 RAYKGSICSPCSRELILHTP 508
Score = 42.2 bits (97), Expect = 0.024, Method: Composition-based stats.
Identities = 21/87 (24%), Positives = 33/87 (38%), Gaps = 13/87 (15%)
Query 242 LTWTNPSIKSVIILKYNIQYRTK---DASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ W +P Y ++YR D +W++I T+ +QDL+ + Y FR
Sbjct 435 INWHHPEKDKAD--SYVLEYRKINRDDEMSWNEIEVCGTSK-----IIQDLENSSTYAFR 487
Query 299 IRCMKEDGKGYWSDWSEEASGITYEDR 325
+R K S S E T
Sbjct 488 VRAYKGSIC---SPCSRELILHTPPAP 511
>sp|A8WQH2|PXDN1_CAEBR Peroxidasin homolog OS=Caenorhabditis briggsae
OX=6238 GN=pxn-1 PE=3 SV=1
Length=1288
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 32/196 (16%), Positives = 61/196 (31%), Gaps = 43/196 (22%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTI---PKEQYTIINRTASSV 89
P + S C + I W N K+Q + N
Sbjct 320 PRDNSYREGSEVKVNC-------EVMGTPKPSITWYHNGVRFASSRKKQLGLSNNVLRIY 372
Query 90 TFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPP---EKPKNLSCIVNEGKKMRC-- 144
F + + + TC + + + + +IS +PP E P+++S + C
Sbjct 373 PF--LEEDSGRYTCEAVNSLGKVSHTFSLDLISSIPPNIYEGPQSVSQNIGGEVVFVCKA 430
Query 145 --------EW--DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNI 194
W DG H++ F + + ++ + K + SC
Sbjct 431 KGNPTPDYTWSFDGSTIGHIKGRFMVSDDGTELXISNIEKKDEGYYSC------------ 478
Query 195 EVWVEAENALGKVTSD 210
A N +G +++D
Sbjct 479 ----MAGNPVGAMSAD 490
>sp|Q9UFD9|RIM3A_HUMAN RIMS-binding protein 3A OS=Homo sapiens
OX=9606 GN=RIMBP3 PE=1 SV=4
Length=1639
Score = 44.8 bits (104), Expect = 0.004, Method: Composition-based stats.
Identities = 37/209 (18%), Positives = 67/209 (32%), Gaps = 27/209 (13%)
Query 223 NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS 282
P L + N S+ + +++ V+ L T + S
Sbjct 994 MAPMQLHLQNVTATSANITWVYSSHRHPHVVYLD--------------DREHALTPAGVS 1039
Query 283 SFTVQDLKPFTEYVFR--IRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSH 340
+T Q L P T Y R +R ++ + YW S + T P P +
Sbjct 1040 CYTFQGLCPGTHYRARVEVRLPRDLLQVYWGTMSSTVTFDTLLAGPPYPP---LDVLVER 1096
Query 341 TQGYRTVQLVWKTL---PPFEANG-KILDYEVTLTRWKS-HLQNYTVNATKLTV---NLT 392
+ + W + +NG ++ Y V K + + T +T L +
Sbjct 1097 HASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTLLEFSQLQVP 1156
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDF 421
++ +L G+S +V DF
Sbjct 1157 LTWQKVSVRTMSLCGESLDSVPAQIPEDF 1185
>sp|Q98930|SORL_CHICK Sortilin-related receptor (Fragment) OS=Gallus
gallus OX=9031 GN=SORL1 PE=2 SV=1
Length=1592
Score = 44.8 bits (104), Expect = 0.005, Method: Composition-based stats.
Identities = 32/136 (24%), Positives = 51/136 (38%), Gaps = 17/136 (13%)
Query 233 SEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPF 292
+ + S + LTW P S YN+ YR S W + T S ++S ++ LKP
Sbjct 1470 TADFSGAITLTWARPKRMSSTSCVYNVYYRMVGESIWKVLE---THSNKTSSVLKVLKPD 1526
Query 293 TEY--VFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQL- 349
Y +++C+ S IT P P + + + + V L
Sbjct 1527 CTYQVKVQVQCL--------SRVYNTNDFITLR-VPEGLPDAPFNLQLALKKEAEGVVLC 1577
Query 350 VWKTLPPFEANGKILD 365
W P A+G I +
Sbjct 1578 SWSA--PVNAHGLIRE 1591
Score = 41.4 bits (95), Expect = 0.057, Method: Composition-based stats.
Identities = 18/130 (14%), Positives = 40/130 (31%), Gaps = 2/130 (2%)
Query 128 KPKNLSCIVNEGKKMRCEW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDY 186
K +NL + + W R + + + TS +
Sbjct 1463 KVQNLQWTADFSGAITLTWARPKRMSSTSCVYNVYYRMVGESIWKVLETHSNKTSSVLKV 1522
Query 187 STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTN 246
+V V+ + ++ V + P+ P NL + +E ++ +W+
Sbjct 1523 LKP-DCTYQVKVQVQCLSRVYNTNDFITLRVPEGLPDAPFNLQLALKKEAEGVVLCSWSA 1581
Query 247 PSIKSVIILK 256
P +I +
Sbjct 1582 PVNAHGLIRE 1591
>sp|Q4R767|FNDC8_MACFA Fibronectin type III domain-containing
protein 8 OS=Macaca fascicularis OX=9541 GN=FNDC8 PE=2 SV=1
Length=324
Score = 44.1 bits (102), Expect = 0.005, Method: Composition-based stats.
Identities = 22/133 (17%), Positives = 47/133 (35%), Gaps = 12/133 (9%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPE------ 275
P+ P + +S ++WT ++ + Y + + + +++P
Sbjct 179 PDTPF---IFEHTVSNSTAVISWTY-ALGKQPVSFYQVLLQEAAETQENELPKAKNRPWI 234
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYK 335
++ + +LKP T Y +R G G W + A+ T D S + +
Sbjct 235 FNKILGTTVKLMELKPNTCYCLTVRAANTAGVGKWCKPYKFATLAT--DFSSFPENNPIQ 292
Query 336 IDPSHTQGYRTVQ 348
I + R +
Sbjct 293 ITVRRKEPQRKIV 305
>sp|O13147|EPHB3_DANRE Ephrin type-B receptor 3 (Fragment) OS=Danio
rerio OX=7955 GN=ephb3 PE=2 SV=1
Length=500
Score = 44.5 bits (103), Expect = 0.005, Method: Composition-based stats.
Identities = 10/44 (23%), Positives = 21/44 (48%), Gaps = 0/44 (0%)
Query 277 TASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
+ +S V+ LK T Y ++R G G +S+ + ++ +
Sbjct 20 VTAQHTSAKVEGLKAGTVYSVQVRARTVAGYGRYSNPVDFSTSL 63
Score = 41.4 bits (95), Expect = 0.036, Method: Composition-based stats.
Identities = 11/42 (26%), Positives = 18/42 (43%), Gaps = 0/42 (0%)
Query 560 TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
G + V + HT + L + T+Y V++ A T G
Sbjct 10 QERGESFSHTVTAQHTSAKVEGLKAGTVYSVQVRARTVAGYG 51
>sp|E4URG0|M28P2_ARTGP Probable zinc metalloprotease MGYG_02393
OS=Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893)
OX=535722 GN=MGYG_02393 PE=3 SV=1
Length=500
Score = 44.1 bits (102), Expect = 0.005, Method: Composition-based stats.
Identities = 20/87 (23%), Positives = 36/87 (41%), Gaps = 6/87 (7%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
+ P P N+ V S+ + K TW P+ + ++ Y I +R+ +A W+
Sbjct 410 MSPGMPRNVRVNTSDLTNDS-KFTWDPPAGGNALVGGYEIVWRSTNAPFWTHKMDVGMVQ 468
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ DL +F IR ++G
Sbjct 469 EAT----IDLSKDNV-IFGIRARGKNG 490
>sp|P27050|CHID_NIACI Chitinase D OS=Niallia circulans OX=1397
GN=chiD PE=1 SV=4
Length=524
Score = 44.1 bits (102), Expect = 0.006, Method: Composition-based stats.
Identities = 13/76 (17%), Positives = 27/76 (36%), Gaps = 9/76 (12%)
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLT 583
+ + V L W+ N + Y ++ + ++S T ++ LT
Sbjct 98 GLTSSLVTDTSVNLTWN---ASTDNVGVTGYEVY------RNGTLVANTSTTTAVVTGLT 148
Query 584 SDTLYMVRMAAYTDEG 599
+ T Y+ + A G
Sbjct 149 AGTTYVFTVKAKDAAG 164
Score = 41.8 bits (96), Expect = 0.032, Method: Composition-based stats.
Identities = 15/78 (19%), Positives = 29/78 (37%), Gaps = 11/78 (14%)
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
+ +S + + LTW + +V + Y + YR ++ ++ V
Sbjct 98 GLTSSLVTDTSVNLTWNASTD-NVGVTGYEV-YRN---------GTLVANTSTTTAVVTG 146
Query 289 LKPFTEYVFRIRCMKEDG 306
L T YVF ++ G
Sbjct 147 LTAGTTYVFTVKAKDAAG 164
>sp|Q8TC99|FNDC8_HUMAN Fibronectin type III domain-containing
protein 8 OS=Homo sapiens OX=9606 GN=FNDC8 PE=1 SV=2
Length=324
Score = 43.7 bits (101), Expect = 0.006, Method: Composition-based stats.
Identities = 18/106 (17%), Positives = 39/106 (37%), Gaps = 10/106 (9%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPE------ 275
P+ P + +S ++WT ++ + Y + + + +++P
Sbjct 179 PDTPF---IFEHTVNNSTAVISWTY-ALGKQPVSFYQLLLQEVAKTQENELPEAKNRPWI 234
Query 276 DTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
++ + +LKP T Y +R G G W + A+ T
Sbjct 235 FNKILGTTVKLMELKPNTCYCLSVRAANTAGVGKWCKPYKFATLAT 280
>sp|P85171|MDGA1_RAT MAM domain-containing glycosylphosphatidylinositol
anchor protein 1 OS=Rattus norvegicus OX=10116 GN=Mdga1
PE=1 SV=1
Length=956
Score = 44.1 bits (102), Expect = 0.007, Method: Composition-based stats.
Identities = 32/136 (24%), Positives = 48/136 (35%), Gaps = 12/136 (9%)
Query 492 YLITVTP-VYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN-EAVLEWDQLPVDVQNG 549
Y +V+ V + S KAY + R+ K+ KN VL+W Q D +
Sbjct 614 YECSVSNDVGSATCLFQVSAKAYSPEFYFDTPNPTRSHKLSKNYSYVLQWTQREPDAVD- 672
Query 550 FIRNYTIFYRTIIGNETAVN-------VDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ NY + R + + V EYTL+ L Y + + YT G D
Sbjct 673 PVLNYRLSIRQLNQHNAMVKAIPVRRVEKGQLLEYTLTDLRVPHSYEIHLTPYTTFGAGD 732
Query 603 GPEFTF--TTPKFAQG 616
T P +
Sbjct 733 MASRVIHYTEPINSPS 748
>sp|Q98936|PTPRG_CHICK Receptor-type tyrosine-protein phosphatase
gamma OS=Gallus gallus OX=9031 GN=PTPRG PE=2 SV=1
Length=1422
Score = 44.1 bits (102), Expect = 0.007, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 34/103 (33%), Gaps = 12/103 (12%)
Query 201 ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNI 259
EN LG S + PP N+ V + L +TW P I+ Y I
Sbjct 335 ENPLGTEASKACST---------PPVNMKVQPVNR--TALLVTWNQPETIYHPPIMNYMI 383
Query 260 QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCM 302
Y + + + + P Y+FR++ +
Sbjct 384 SYSWTKNEDEKEKTFTKDSDKDLKAIISHVSPDILYLFRVQAV 426
Score = 40.2 bits (92), Expect = 0.11, Method: Composition-based stats.
Identities = 17/89 (19%), Positives = 33/89 (37%), Gaps = 6/89 (7%)
Query 512 AYLKQAPPSKGP-TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNV 570
S P ++ + V + ++ W+Q P + + I NY I Y +
Sbjct 339 GTEASKACSTPPVNMKVQPVNRTALLVTWNQ-PETIYHPPIMNYMISYSWTKNEDEKEKT 397
Query 571 ----DSSHTEYTLSSLTSDTLYMVRMAAY 595
+ +S ++ D LY+ R+ A
Sbjct 398 FTKDSDKDLKAIISHVSPDILYLFRVQAV 426
>sp|O75147|OBSL1_HUMAN Obscurin-like protein 1 OS=Homo sapiens
OX=9606 GN=OBSL1 PE=1 SV=4
Length=1896
Score = 44.1 bits (102), Expect = 0.008, Method: Composition-based stats.
Identities = 67/464 (14%), Positives = 127/464 (27%), Gaps = 55/464 (12%)
Query 203 ALGKVTSDHINFDPVYK-VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
+LG + + K P PP + + + + LTW P Y ++
Sbjct 498 SLGNSRTTTLLRVKCVKHSPPGPP--ILAEMFKGHKNTVLLTWKPPEPAPETPFIYRLER 555
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQD--LKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
+ + W Q + + V + +Y FRI C ++
Sbjct 556 QEVGSEDWIQC---FSIEKAGAVEVPGDCVPSEGDYRFRI-CTVSGHGRSPHVVFHGSAH 611
Query 320 ITYEDRPSKAPSFWYKIDPSH---TQGYRTVQL-VW----KTLPPFEANGKILDYEVTLT 371
+ R D + T+ W + L E G++ +
Sbjct 612 LVPTARLVAGLEDVQVYDGEDAVFSLDLSTIIQGTWFLNGEELKSNEPEGQVEPGALRYR 671
Query 372 RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
+ LQ +L ++ + L + G D+A LTI P +
Sbjct 672 IEQKGLQ------HRLILHAVKHQDSGALVGFSCPGVQDSAALTIQESPVHILSPQDRVS 725
Query 432 -AFPKDNMLWVEWTTPRESVKKYILEWCVLSDK-APCITDWQQEDGTVHRTYLRG----N 485
F + + R + W K + DG HR L +
Sbjct 726 LTFTTSERVVLTCELSR---VDFPATWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQD 782
Query 486 LAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVD 545
E +C V+ + P ++ V + +L + VD
Sbjct 783 SGEFECRTEGVSAFFGVTVQDPPVHIVDPRE-------HVFVHAITSECVMLACE---VD 832
Query 546 VQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
++ +R Y + + + H L + + A G E
Sbjct 833 REDAPVRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVA--------GDE 884
Query 606 FTFTTPKFAQGEIEAIVVPVCLAFLLTTL---LGVLFCFNKRDL 646
+ T ++ + +V + + VL C R
Sbjct 885 CAYFTVTI--TDVSSWIVYPSGKVYVAAVRLERVVLTCELCRPW 926
>sp|A0A8M9QN10|ANKF1_DANRE Ankyrin repeat and fibronectin type-III
domain-containing protein 1 OS=Danio rerio OX=7955 GN=ankfn1
PE=4 SV=1
Length=1418
Score = 44.1 bits (102), Expect = 0.008, Method: Composition-based stats.
Identities = 23/130 (18%), Positives = 47/130 (36%), Gaps = 17/130 (13%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSV-IILKYNIQYR--TKDASTWSQIPPEDT 277
+P P L V S S+ L +++ P+ + ++ KY +++ + ++ E+
Sbjct 553 QPEAP--LMVRLSVTGSTTLTVSFQEPASMNSAVVTKYKVEWSCLKDFSLLAGELILENL 610
Query 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
S + T+ L +Y ++ G G PS PS W D
Sbjct 611 QSLK--CTITGLTMGRQYYVQVSAYNMKGWGPAQ----------LSQPPSAVPSNWKDCD 658
Query 338 PSHTQGYRTV 347
++ +
Sbjct 659 GRESRRRGHI 668
>sp|D4D8N9|M28P2_TRIVH Probable zinc metalloprotease TRV_03476
OS=Trichophyton verrucosum (strain HKI 0517) OX=663202 GN=TRV_03476
PE=3 SV=1
Length=497
Score = 43.3 bits (100), Expect = 0.009, Method: Composition-based stats.
Identities = 21/87 (24%), Positives = 37/87 (43%), Gaps = 6/87 (7%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
+ P P N+ V N+ LS+ K +W P+ + ++ Y I +R+ A W+
Sbjct 407 MSPGMPRNVRV-NTNALSNDSKFSWDPPAGGNALVGGYEIVWRSTTAPFWTHKMDVGMVQ 465
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ DL +F IR ++G
Sbjct 466 EAT----IDLSKDNV-IFGIRARGKNG 487
>sp|Q5BPT4|VIL3_ARATH VIN3-like protein 3 OS=Arabidopsis thaliana
OX=3702 GN=VIL3 PE=2 SV=1
Length=529
Score = 43.3 bits (100), Expect = 0.009, Method: Composition-based stats.
Identities = 24/133 (18%), Positives = 51/133 (38%), Gaps = 16/133 (12%)
Query 502 DGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTI 561
DG P +I+ +K +R + V + + G +Y + YR +
Sbjct 302 DGLPLPSTIQGSMK---------IRIESVLATSVTFDIEAEESFSW-GDTNHYRMVYRKV 351
Query 562 IGNETAVNVD------SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ 615
++ ++ SSH +T+ LT T Y ++ +++ EF +T
Sbjct 352 SEKHSSKDLTRELFSTSSHQRFTVMELTPATEYWFKIVSFSGVEELSVDEFIVSTKTLQD 411
Query 616 GEIEAIVVPVCLA 628
E+ A+++ +
Sbjct 412 EEVAAVLLNMSNC 424
>sp|C5FP82|M28P2_ARTOC Probable zinc metalloprotease MCYG_04217
OS=Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) OX=554155
GN=MCYG_04217 PE=3 SV=1
Length=508
Score = 43.3 bits (100), Expect = 0.010, Method: Composition-based stats.
Identities = 20/87 (23%), Positives = 35/87 (40%), Gaps = 6/87 (7%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
+ P P N+ V S+ + K TW P+ + + Y I +R+ A W+ +
Sbjct 418 MSPGMPRNVRVDTSDLSNDS-KFTWDPPAGGNAGVGGYEIVWRSTIAPFWTNVMDVGMVQ 476
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ DL +F IR ++G
Sbjct 477 AAT----IDLSKDNV-IFGIRARGKNG 498
>sp|Q9DAM9|FANK1_MOUSE Fibronectin type 3 and ankyrin repeat domains
1 protein OS=Mus musculus OX=10090 GN=Fank1 PE=1 SV=1
Length=344
Score = 42.9 bits (99), Expect = 0.010, Method: Composition-based stats.
Identities = 17/101 (17%), Positives = 36/101 (36%), Gaps = 6/101 (6%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN-IQYRTKDASTWSQIPPEDTAS 279
KP+PP V + ++L W + + +++ ++
Sbjct 11 KPHPPVVGKVTHH-----SIELYWDLEQKEKRQGPQEQWLRFSIEEEDPKMHSYGVIYTG 65
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
+ V+ L+P T Y FR++ G+ +S A+
Sbjct 66 YATRHVVEGLEPRTLYKFRLKVTSPSGEYEYSPVVSVATTR 106
Score = 39.5 bits (90), Expect = 0.13, Method: Composition-based stats.
Identities = 20/114 (18%), Positives = 32/114 (28%), Gaps = 8/114 (7%)
Query 518 PPSKGPTVRTK-KVGKNEAVLEWDQLPVDVQNGFIRNY-TIFYRTIIG--NETAVNVDSS 573
P P KV + L WD + + G + + V
Sbjct 7 VPLSKPHPPVVGKVTHHSIELYWDLEQKEKRQGPQEQWLRFSIEEEDPKMHSYGVIYTGY 66
Query 574 HTEYTLSSLTSDTLYMVRMAAYTDEG----GKDGPEFTFTTPKFAQGEIEAIVV 623
T + + L TLY R+ + G T P ++ A+ V
Sbjct 67 ATRHVVEGLEPRTLYKFRLKVTSPSGEYEYSPVVSVATTREPISSEHFHRAVSV 120
>sp|D4AM42|M28P2_ARTBC Probable zinc metalloprotease ARB_04732
OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)
OX=663331 GN=ARB_04732 PE=3 SV=1
Length=497
Score = 43.3 bits (100), Expect = 0.010, Method: Composition-based stats.
Identities = 19/87 (22%), Positives = 34/87 (39%), Gaps = 6/87 (7%)
Query 220 VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAS 279
+ P P N+ V + + K +W P+ + ++ Y I +R+ A W+
Sbjct 407 MSPGMPRNVRVNTTALSNDS-KFSWDPPAGGNALVGGYEIVWRSTTAPFWTHKMDVGMVQ 465
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDG 306
+ DL VF IR ++G
Sbjct 466 EAT----IDLSKDNV-VFGIRARGKNG 487
>sp|D2HFT7|LRFN3_AILME Leucine-rich repeat and fibronectin type-III
domain-containing protein 3 OS=Ailuropoda melanoleuca
OX=9646 GN=LRFN3 PE=3 SV=1
Length=628
Score = 43.3 bits (100), Expect = 0.010, Method: Composition-based stats.
Identities = 45/252 (18%), Positives = 73/252 (29%), Gaps = 41/252 (16%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEW-DG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
+P +P L C + R W GR + T
Sbjct 307 VPAGRPAALRCRAVGDPEPRVRWVSPQGRLVGNSSRARAFPNGTLELLVTEPGDGGIFTC 366
Query 182 CTVDYSTVYFVNIEVWV--EAENALGKVTS--DHINFDPVYKVKP--------------N 223
+ + +E+ V L TS + DP P
Sbjct 367 IAANAAGEATAAVELTVGPPPPPQLANSTSCDPPRDGDPDALTPPSAASASAAAKAADTG 426
Query 224 PPHNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRS 282
PP + V +E ++ + W P + + I Y IQY ++S + +
Sbjct 427 PPTDRGVQVTEHGATAALVQW--PDQRPIPGIRMYQIQY---NSSADDILVYRMIPADSH 481
Query 283 SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE-----DRPSKAPSFWYKID 337
SF + DL Y + + EDG A+G+T R S P+
Sbjct 482 SFLLSDLASGRTYDLCVLAVYEDG----------ATGLTATRPVGCARFSTEPALRPCGA 531
Query 338 PSHTQGYRTVQL 349
P T+ +
Sbjct 532 PHAPFLGGTMII 543
>sp|Q8N957|ANKF1_HUMAN Ankyrin repeat and fibronectin type-III
domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKFN1
PE=2 SV=3
Length=1146
Score = 43.3 bits (100), Expect = 0.011, Method: Composition-based stats.
Identities = 15/107 (14%), Positives = 38/107 (36%), Gaps = 9/107 (8%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNP-SIKSVIILKYNIQYRTKDASTWSQIPPEDTAST 280
P P N+ ++ + S+ L +++ P S+ + ++ +Y +++ + +
Sbjct 268 PEMPTNVCLMVT--SSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQ 325
Query 281 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
T+ L +Y ++ G W + PS
Sbjct 326 TLRCTITGLTMGQQYFVQVSAYNMKG------WGPAQTTTPACASPS 366
>sp|P36909|CHIT_STRLI Chitinase C OS=Streptomyces lividans OX=1916
GN=chiC PE=2 SV=1
Length=619
Score = 43.3 bits (100), Expect = 0.012, Method: Composition-based stats.
Identities = 28/131 (21%), Positives = 37/131 (28%), Gaps = 22/131 (17%)
Query 484 GNLAESKCYLITVTPVYADGPGSPE-------SIKAYL--KQAPPSKGPTVRTKKVGKNE 534
G LA GPGSP S A PS T +
Sbjct 101 GTLAPGASVSF---GFNGSGPGSPSNCKLNGGSCDGTSVPGDAAPSAPGTPTASNITDTS 157
Query 535 AVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAA 594
L W D ++NY + + A + T YT + LT T Y + A
Sbjct 158 VKLSWSAATDDKG---VKNYDVL------RDGAKVATVTGTTYTDNGLTKGTAYSYSVKA 208
Query 595 Y-TDEGGKDGP 604
T +
Sbjct 209 RDTADQTGPAS 219
>sp|Q3TYX2|LRN4L_MOUSE LRRN4 C-terminal-like protein OS=Mus musculus
OX=10090 GN=Lrrn4cl PE=2 SV=1
Length=239
Score = 41.8 bits (96), Expect = 0.017, Method: Composition-based stats.
Identities = 15/115 (13%), Positives = 39/115 (34%), Gaps = 12/115 (10%)
Query 520 SKGPTVRTKKV--GKNEAVLEWDQLPVDVQNGFIRNY-TIFYRTIIGNETAVNVDSSHTE 576
+ P + ++ + AV+ W + +Y + + + + + ++++
Sbjct 83 PEPPRLGEVQIMAEEGYAVVHW-----CAPFSPVSHYWLLLWESNGAPQKSAPLNATVRR 137
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLL 631
L L Y++ + A D G + P P+ C F++
Sbjct 138 AELKGLKPGVAYVLCVVAANDAGESNVPGAEVEGPEN----WTGPSFGPCRKFIM 188
Score = 37.1 bits (84), Expect = 0.47, Method: Composition-based stats.
Identities = 20/107 (19%), Positives = 35/107 (33%), Gaps = 6/107 (6%)
Query 419 CDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVH 478
+ +++ ++ V W P V Y W +L + + TV
Sbjct 80 DQQPEPPRLGEVQIMAEEGYAVVHWCAPFSPVSHY---WLLLWESNGAPQKSAPLNATVR 136
Query 479 RTYLRGNLAESKCYLITVTPVYADGPGSPE--SIKAYLKQAPPSKGP 523
R L+G L Y++ V G + ++ PS GP
Sbjct 137 RAELKG-LKPGVAYVLCVVAANDAGESNVPGAEVEGPENWTGPSFGP 182
>sp|D3YYU8|OBSL1_MOUSE Obscurin-like protein 1 OS=Mus musculus
OX=10090 GN=Obsl1 PE=1 SV=1
Length=1804
Score = 42.9 bits (99), Expect = 0.018, Method: Composition-based stats.
Identities = 55/358 (15%), Positives = 99/358 (28%), Gaps = 36/358 (10%)
Query 203 ALGKVTSDHINFDPVYK-VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
+LG + + K P PP + V + + + LTW P Y ++
Sbjct 498 SLGNSRTTTLLRVKCVKHSPPGPP--VMVEMFKGQKNKVLLTWKPPEPPPETSFIYRLER 555
Query 262 RTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE--YVFRIRCMKEDGKGYWSDWSEEASG 319
+ + W I + D P TE Y FRI C + ++
Sbjct 556 QEVGSDDW--IQCFSIEKAGAVEVPGDCVP-TEGDYHFRI-CTVSEHGRSPHVVFNGSAH 611
Query 320 ITYEDRPSKAPSFWYKIDPSHTQGYRTVQL----VW----KTLPPFEANGKILDYEVTLT 371
+ R D + W + L E G++ +
Sbjct 612 LVPTARLVSGLEDVQVYDGEDAVFSLDLSAIIQGSWFLNGEQLQSNEPEGQVEPGALRYR 671
Query 372 RWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLK 431
+ LQ +L + R L + G D+A LTI P +
Sbjct 672 IEQKGLQ------HRLILQAVKHRDSGALVGFSCPGVQDSAALTIQESSVHILSPQDKVS 725
Query 432 -AFPKDNMLWVEWTTPRESVKKYILEWCVLSDK-APCITDWQQEDGTVHRTYLRG----N 485
F + + R + W K + + +G HR L +
Sbjct 726 LTFTTSERVVLTCELSR---VDFPATWYKDGQKVEESESLIVKTEGRKHRLILPEAQVRD 782
Query 486 LAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVG----KNEAVLEW 539
E +C V+ + P ++ T ++ + + + W
Sbjct 783 SGEFECRTEGVSAFFGVTVQDPPVHIVNPQEHVFVHAITSECVRLTCEVDREDTTVHW 840
Score = 38.3 bits (87), Expect = 0.50, Method: Composition-based stats.
Identities = 16/93 (17%), Positives = 36/93 (39%), Gaps = 5/93 (5%)
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNV 570
+K +PP V K KN+ +L W + FI Y + + + ++ ++
Sbjct 512 CVKHSPPGPPVMVEMFKGQKNKVLLTWKPPEPPPETSFI--YRLERQEVGSDDWIQCFSI 569
Query 571 D-SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ + E + ++ Y R+ ++ G
Sbjct 570 EKAGAVEVPGDCVPTEGDYHFRICTVSEHGRSP 602
>sp|Q9BTN0|LRFN3_HUMAN Leucine-rich repeat and fibronectin type-III
domain-containing protein 3 OS=Homo sapiens OX=9606 GN=LRFN3
PE=2 SV=1
Length=628
Score = 42.5 bits (98), Expect = 0.019, Method: Composition-based stats.
Identities = 44/250 (18%), Positives = 72/250 (29%), Gaps = 39/250 (16%)
Query 124 LPPEKPKNLSCIVNEGKKMRCEW-DG-GRETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
+P +P L C + R W GR + T
Sbjct 307 VPAGRPAALRCRAVGDPEPRVRWVSPQGRLLGNSSRARAFPNGTLELLVTEPGDGGIFTC 366
Query 182 CTVDYSTVYFVNIEVWV--EAENALGKVTS--DHINFDPVYKVKP------------NPP 225
+ + +E+ V L TS + DP P PP
Sbjct 367 IAANAAGEATAAVELTVGPPPPPQLANSTSCDPPRDGDPDALTPPSAASASAKVADTGPP 426
Query 226 HNLSVINSEELSSILKLTWTNPSIKSVI-ILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
+ V +E ++ + W P + + I Y IQY ++S + + SF
Sbjct 427 TDRGVQVTEHGATAALVQW--PDQRPIPGIRMYQIQY---NSSADDILVYRMIPAESRSF 481
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYE-----DRPSKAPSFWYKIDPS 339
+ DL Y + + ED A+G+T R S P+ P
Sbjct 482 LLTDLASGRTYDLCVLAVYED----------SATGLTATRPVGCARFSTEPALRPCGAPH 531
Query 340 HTQGYRTVQL 349
T+ +
Sbjct 532 APFLGGTMII 541
>sp|P38939|APU_THEP3 Amylopullulanase OS=Thermoanaerobacter pseudethanolicus
(strain ATCC 33223 / 39E) OX=340099 GN=apu PE=1
SV=2
Length=1481
Score = 42.5 bits (98), Expect = 0.020, Method: Composition-based stats.
Identities = 19/98 (19%), Positives = 36/98 (37%), Gaps = 7/98 (7%)
Query 219 KVKP----NPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
V P PP L + SS + L W+ + +V I Y I Y++ + +
Sbjct 1150 IVVPSNDVEPPTALGLQQPGIESSRVTLNWSLSTD-NVAIYGYEI-YKSLSETGPF-VKI 1206
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSD 312
A T ++ D+ Y +++ + S+
Sbjct 1207 ATVADTVYNYVDTDVVNGKVYYYKVVAVDTSFNRTASN 1244
Score = 41.8 bits (96), Expect = 0.039, Method: Composition-based stats.
Identities = 27/148 (18%), Positives = 56/148 (38%), Gaps = 14/148 (9%)
Query 377 LQNYTVNATKLTVNLTNDRYLAT---LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAF 433
+ + T L+ Y + V + A +++ P + A P+ DLKA
Sbjct 879 TTKFVRDGVAFTDALSGKTYTVRDGQIVVEVVALDG-AILISDPGQNLTAPQPITDLKAV 937
Query 434 PKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHR-TYLRGNLAESKCY 492
+ + + W+ +V + +++ V + TY+ ++ Y
Sbjct 938 SGNGQVDLSWSAVDRAVSY------NIYRSTVKGGLYEKIASNVTQITYIDTDVTNGLKY 991
Query 493 LITVTPVYADGPGSPESIKAYLKQAPPS 520
+ +VT V +DG S S + +A P+
Sbjct 992 VYSVTAVDSDGNESALSNEV---EAYPA 1016
>sp|Q5IS82|NTRK3_SAIBB NT-3 growth factor receptor OS=Saimiri
boliviensis boliviensis OX=39432 GN=NTRK3 PE=2 SV=1
Length=825
Score = 42.5 bits (98), Expect = 0.020, Method: Composition-based stats.
Identities = 32/227 (14%), Positives = 66/227 (29%), Gaps = 44/227 (19%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
V+ + C + + W T +N T +V ++
Sbjct 220 TVREGDSAVITC-------NGSGSPLPDVDWIVTGLQSINTHQTNLNWT--NVHAINLTL 270
Query 97 LNIQLTCNILTFGQLEQNVYG-----ITIISGLPPEKPKNLSCIVNEGK-----KMRCEW 146
+N+ N T + +NV G + + P P+ +S E + +
Sbjct 271 VNVTSEDNGFTLTCIAENVVGMSNASVALTVYYP---PRVVSLEEPELRLEHCIEFVVRG 327
Query 147 DGGRETHLETNFTLKSEWATHKFA----DCKAKRDTPTSCTVDYSTVYFVNIEVWVEAEN 202
+ T + L + + + + + C + ++ N + A+N
Sbjct 328 NPP-----PTLYWLHNGQPLRESKIIHVEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKN 382
Query 203 ALGKV-------------TSDHINFDPVYKVKPNPPHNLSVINSEEL 236
LG NF +V P PP ++ E+
Sbjct 383 PLGTANQTINGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDT 429
>sp|Q5IS37|NTRK3_PANTR NT-3 growth factor receptor OS=Pan troglodytes
OX=9598 GN=NTRK3 PE=2 SV=1
Length=825
Score = 42.5 bits (98), Expect = 0.021, Method: Composition-based stats.
Identities = 35/224 (16%), Positives = 66/224 (29%), Gaps = 38/224 (17%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
V+ N C + + W T +N T +V ++
Sbjct 220 TVREGDNAVITC-------NGSGSPLPDVDWIVTGLQSINTHQTNLNWT--NVHAINLTL 270
Query 97 LNIQLTCNILTFGQLEQNVYG-----ITIISGLPPEKPKNLSCIVNEGK-----KMRCEW 146
+N+ N T + +NV G + + P P+ +S E + +
Sbjct 271 VNVTSEDNGFTLTCIAENVVGMSNASVALTVYYP---PRVVSLEEPELRLEHCIEFVVRG 327
Query 147 DGGRETH-LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
+ H L L+ H + + + C + ++ N + A+N LG
Sbjct 328 NPPPTLHWLHNGQPLRESKIIH--VEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLG 385
Query 206 KV-------------TSDHINFDPVYKVKPNPPHNLSVINSEEL 236
NF +V P PP ++ E+
Sbjct 386 TANQTISGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDT 429
>sp|Q5IFJ9|NTRK3_MACFA NT-3 growth factor receptor OS=Macaca fascicularis
OX=9541 GN=NTRK3 PE=2 SV=1
Length=825
Score = 42.5 bits (98), Expect = 0.021, Method: Composition-based stats.
Identities = 35/224 (16%), Positives = 66/224 (29%), Gaps = 38/224 (17%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
V+ N C + + W T +N T +V ++
Sbjct 220 TVREGDNAVITC-------NGSGSPLPDVDWIVTGLQSINTHQTNLNWT--NVHAINLTL 270
Query 97 LNIQLTCNILTFGQLEQNVYG-----ITIISGLPPEKPKNLSCIVNEGK-----KMRCEW 146
+N+ N T + +NV G + + P P+ +S E + +
Sbjct 271 VNVTSEDNGFTLTCIAENVVGMSNASVALTVYYP---PRVVSLEEPELRLEHCIEFVVRG 327
Query 147 DGGRETH-LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
+ H L L+ H + + + C + ++ N + A+N LG
Sbjct 328 NPPPTLHWLHNGQPLRESKIIH--VEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLG 385
Query 206 KV-------------TSDHINFDPVYKVKPNPPHNLSVINSEEL 236
NF +V P PP ++ E+
Sbjct 386 TANQTINGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDT 429
>sp|Q16288|NTRK3_HUMAN NT-3 growth factor receptor OS=Homo sapiens
OX=9606 GN=NTRK3 PE=1 SV=2
Length=839
Score = 42.5 bits (98), Expect = 0.021, Method: Composition-based stats.
Identities = 35/224 (16%), Positives = 66/224 (29%), Gaps = 38/224 (17%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
V+ N C + + W T +N T +V ++
Sbjct 220 TVREGDNAVITC-------NGSGSPLPDVDWIVTGLQSINTHQTNLNWT--NVHAINLTL 270
Query 97 LNIQLTCNILTFGQLEQNVYG-----ITIISGLPPEKPKNLSCIVNEGK-----KMRCEW 146
+N+ N T + +NV G + + P P+ +S E + +
Sbjct 271 VNVTSEDNGFTLTCIAENVVGMSNASVALTVYYP---PRVVSLEEPELRLEHCIEFVVRG 327
Query 147 DGGRETH-LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
+ H L L+ H + + + C + ++ N + A+N LG
Sbjct 328 NPPPTLHWLHNGQPLRESKIIH--VEYYQEGEISEGCLLFNKPTHYNNGNYTLIAKNPLG 385
Query 206 KV-------------TSDHINFDPVYKVKPNPPHNLSVINSEEL 236
NF +V P PP ++ E+
Sbjct 386 TANQTINGHFLKEPFPESTDNFILFDEVSPTPPITVTHKPEEDT 429
>sp|Q9D2H8|FNDC8_MOUSE Fibronectin type III domain-containing
protein 8 OS=Mus musculus OX=10090 GN=Fndc8 PE=2 SV=1
Length=321
Score = 41.8 bits (96), Expect = 0.022, Method: Composition-based stats.
Identities = 27/167 (16%), Positives = 50/167 (30%), Gaps = 10/167 (6%)
Query 207 VTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDA 266
+ +D + V + P + S ++WT + K + Y + +
Sbjct 158 LDTDTSSTRSESSVVLDVPEVPFICEHTVGDSTAVISWTYAAGKQQ-VSFYQVLLQEATK 216
Query 267 STWSQIPPEDTAS------TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGI 320
P T ++ + +LK T Y +R G G W + A+
Sbjct 217 PADKDTPKIKTRPWIFNKILGTTVKLMELKSNTSYCLTVRAANTAGVGKWCKPYKFATVS 276
Query 321 T-YEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDY 366
T + P P RTV + + + E + Y
Sbjct 277 TDFNSFPETNP--IQVTVQRKQPHRRTVSMTMEEMRRLEDLEYLYPY 321
>sp|P22080|ONCA_HYDTA Oncosphere antigen A (Fragment) OS=Hydatigena
taeniaeformis OX=6205 GN=ONCA PE=2 SV=1
Length=318
Score = 41.8 bits (96), Expect = 0.022, Method: Composition-based stats.
Identities = 19/76 (25%), Positives = 29/76 (38%), Gaps = 3/76 (4%)
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTL 579
S V+ + + + A + WD P G I YTI + T V V +S Y
Sbjct 5 SIPQNVQIEAIDPHTARMTWD--PPAKSYGSIIGYTIQWSTDDLWLEQVKV-ASDNSYDF 61
Query 580 SSLTSDTLYMVRMAAY 595
L S + + A+
Sbjct 62 KDLQSQQTIVASILAH 77
Score = 41.0 bits (94), Expect = 0.039, Method: Composition-based stats.
Identities = 45/300 (15%), Positives = 92/300 (31%), Gaps = 31/300 (10%)
Query 127 EKPKNLSCIVNEGKKMRCEWDGGRETHLETN-FTLKSEWATHKFADCKAKRDTPTSCTVD 185
P+N+ + R WD +++ +T++ W+T + K + S
Sbjct 5 SIPQNVQIEAIDPHTARMTWDPPAKSYGSIIGYTIQ--WSTDDLWLEQVKVASDNS-YDF 61
Query 186 YSTVYFVNIEVWVEAENAL----------GKVTSDHINFDPVYKVKPNPPHNLSV-INSE 234
I + A + + T + +V P + + E
Sbjct 62 KDLQSQQTIVASILAHHRPDTSVKFEYIGTRSTPVKVTTPLPSRVMKKPSFRATYCEDLE 121
Query 235 ELSSILKLTWTNPSIKSVIILKYNIQYRTKDAS---TWSQIPPEDTASTRSSFTVQDLKP 291
EL ++ +P + + + R DA +W + + + + ++ L P
Sbjct 122 ELDMLIH----DPEEVVGMFGGFEVLMRAGDAELLKSWQSV--VNLTAEERRYKLKGLVP 175
Query 292 FTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVW 351
Y +R + + + S+ +E S + + T+++ W
Sbjct 176 SLPYAVTVRGVALPSRRF-SELAEPVHFKISRAEQSVPQNVDMQAT-----DPHTIEMTW 229
Query 352 KTLP-PFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSD 410
P P A V +TR L +V T A++ V KS
Sbjct 230 DCRPNPTVALLATPSAGVAITRSSRSLHLASVQLYTFTGLEPQVSLSASICVHYKPQKSP 289
Score = 38.7 bits (88), Expect = 0.20, Method: Composition-based stats.
Identities = 40/237 (17%), Positives = 70/237 (30%), Gaps = 30/237 (13%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P N+ + + ++TW P+ I+ Y IQ+ T D + ++ +S+
Sbjct 7 PQNVQIEAID--PHTARMTWDPPAKSYGSIIGYTIQWSTDD-----LWLEQVKVASDNSY 59
Query 285 TVQDLKPFTEYVFRIRCM----KEDGKGYWSDWSEEASGITY-EDRPSKAPSFWYKIDPS 339
+DL+ V I Y S T R K PSF +
Sbjct 60 DFKDLQSQQTIVASILAHHRPDTSVKFEYIGTRSTPVKVTTPLPSRVMKKPSF--RATYC 117
Query 340 HTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSH---LQNYTVNAT------KLTVN 390
+ + P E G +EV + + VN T KL
Sbjct 118 EDLEELDMLIH----DPEEVVGMFGGFEVLMRAGDAELLKSWQSVVNLTAEERRYKLKGL 173
Query 391 LTNDRYLATL--TVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKD-NMLWVEWT 444
+ + Y T+ S+ A ++ D + + + W
Sbjct 174 VPSLPYAVTVRGVALPSRRFSELAEPVHFKISRAEQSVPQNVDMQATDPHTIEMTWD 230
>sp|P0C6Q7|TAGA_VIBCH ToxR-activated gene A lipoprotein OS=Vibrio
cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
OX=243277 GN=tagA PE=3 SV=1
Length=1002
Score = 42.5 bits (98), Expect = 0.023, Method: Composition-based stats.
Identities = 12/95 (13%), Positives = 33/95 (35%), Gaps = 3/95 (3%)
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT 575
+ P + K V +EWD++ + +Y + E + + + +
Sbjct 44 KKPSRPIIDEKNKGVTDTSVTIEWDKIECEKNFS---HYNVIVYRKDRIEDVITIRTRNN 100
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ L ++ Y + +++ + + F T
Sbjct 101 SVFIDDLKPNSQYSIDVSSCLHSACSESAKIEFIT 135
Score = 38.7 bits (88), Expect = 0.30, Method: Composition-based stats.
Identities = 24/146 (16%), Positives = 44/146 (30%), Gaps = 13/146 (9%)
Query 183 TVDYSTVYFVNIEVWVEAE--NALGKVTSDHINFDPVYKVKPNPPHNLSV--INSEELSS 238
V YS + V+ + + N ++D DP + P + N +
Sbjct 2 VVRYSLLMKVSFAILIFLVGCNENATSSNDQYLTDPDISEQTKKPSRPIIDEKNKGVTDT 61
Query 239 ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ + W + I YR I + +S + DLKP ++Y
Sbjct 62 SVTIEWDKIECEKNFSHYNVIVYRKDRIEDVITIRTRN-----NSVFIDDLKPNSQYSID 116
Query 299 IRCMKEDGKGYWSDWSEEASGITYED 324
+ S + IT +
Sbjct 117 VSSCLHSACSE----SAKIEFITLNE 138
>sp|Q92357|CFR1_SCHPO Cell fusion protein cfr1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=cfr1 PE=3
SV=1
Length=620
Score = 42.2 bits (97), Expect = 0.023, Method: Composition-based stats.
Identities = 29/121 (24%), Positives = 43/121 (36%), Gaps = 9/121 (7%)
Query 508 ESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA 567
+ I Q PS P ++ K + VLEWD L + YR +
Sbjct 69 KEIFETYGQKLPS-PPVLKLKNATQTSIVLEWDPLQLSTAR---LKSLCLYRNNVRVLNI 124
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCL 627
N ++H LS L+ DT Y + T G T T + I+ + VC+
Sbjct 125 SNPMTTHNA-KLSGLSLDTEYDFSLVLDTTAGTFPSKHITIKTLRM----IDLTGIQVCV 179
Query 628 A 628
Sbjct 180 G 180
>sp|A5F398|TAGA_VIBC3 ToxR-activated gene A lipoprotein OS=Vibrio
cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa
395 / O395) OX=345073 GN=tagA PE=3 SV=2
Length=1002
Score = 42.5 bits (98), Expect = 0.023, Method: Composition-based stats.
Identities = 12/95 (13%), Positives = 33/95 (35%), Gaps = 3/95 (3%)
Query 516 QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT 575
+ P + K V +EWD++ + +Y + E + + + +
Sbjct 44 KKPSRPIIDEKNKGVTDTSVTIEWDKIECEKNFS---HYNVIVYRKDRIEDVITIRTRNN 100
Query 576 EYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ L ++ Y + +++ + + F T
Sbjct 101 SVFIDDLKPNSQYSIDVSSCLHSACSESAKIEFIT 135
Score = 38.7 bits (88), Expect = 0.31, Method: Composition-based stats.
Identities = 24/146 (16%), Positives = 44/146 (30%), Gaps = 13/146 (9%)
Query 183 TVDYSTVYFVNIEVWVEAE--NALGKVTSDHINFDPVYKVKPNPPHNLSV--INSEELSS 238
V YS + V+ + + N ++D DP + P + N +
Sbjct 2 VVRYSLLMKVSFAILIFLVGCNENATSSNDQYLTDPDISEQTKKPSRPIIDEKNKGVTDT 61
Query 239 ILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFR 298
+ + W + I YR I + +S + DLKP ++Y
Sbjct 62 SVTIEWDKIECEKNFSHYNVIVYRKDRIEDVITIRTRN-----NSVFIDDLKPNSQYSID 116
Query 299 IRCMKEDGKGYWSDWSEEASGITYED 324
+ S + IT +
Sbjct 117 VSSCLHSACSE----SAKIEFITLNE 138
>sp|P86861|FND_MYTCA Fibronectin type III domain-containing protein
(Fragment) OS=Mytilus californianus OX=6549 PE=1 SV=1
Length=225
Score = 40.6 bits (93), Expect = 0.031, Method: Composition-based stats.
Identities = 20/107 (19%), Positives = 42/107 (39%), Gaps = 8/107 (7%)
Query 226 HNLSVINSE-ELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWS---QIPPEDTASTR 281
N+ V ++ + S + + W P ++Y + + D + ++ ST+
Sbjct 108 TNVIVESTTIDNVSSIVVKWDPPFNPPE-NMQYKVYFVPVDQNGMQTAGEVVFRICDSTQ 166
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSK 328
+ ++ DL P + Y RIR + S + T + PS+
Sbjct 167 TIASITDLTPRSRY--RIR-VGAVAGAVAEGASMPLNVKTPDIIPSR 210
Score = 39.1 bits (89), Expect = 0.100, Method: Composition-based stats.
Identities = 15/80 (19%), Positives = 31/80 (39%), Gaps = 17/80 (21%)
Query 524 TVRTKKVG---KNEAVLEWDQL--PVDVQNGFIRNYTIFYRTIIGN------ETAVNV-D 571
V + + V++WD P + Y +++ + N E + D
Sbjct 109 NVIVESTTIDNVSSIVVKWDPPFNPPEN-----MQYKVYFVPVDQNGMQTAGEVVFRICD 163
Query 572 SSHTEYTLSSLTSDTLYMVR 591
S+ T +++ LT + Y +R
Sbjct 164 STQTIASITDLTPRSRYRIR 183
Score = 34.1 bits (76), Expect = 4.1, Method: Composition-based stats.
Identities = 14/111 (13%), Positives = 26/111 (23%), Gaps = 5/111 (5%)
Query 431 KAFPKDNMLWVEWTTP--RESVKKYILEWCVLSDKAPCITDWQ--QEDGTVHRTYLRGNL 486
+ + V+W P +Y + + + + + +L
Sbjct 115 TTIDNVSSIVVKWDPPFNPPENMQYKVYFVPVDQNGMQTAGEVVFRICDSTQTIASITDL 174
Query 487 AESKCYLITVTPVYADGPGSPE-SIKAYLKQAPPSKGPTVRTKKVGKNEAV 536
Y I V V + PS+ V K N
Sbjct 175 TPRSRYRIRVGAVAGAVAEGASMPLNVKTPDIIPSRVRNVMVKSSTANTIT 225
>sp|D3ZZ80|OBSL1_RAT Obscurin-like protein 1 OS=Rattus norvegicus
OX=10116 GN=Obsl1 PE=2 SV=3
Length=1805
Score = 42.2 bits (97), Expect = 0.033, Method: Composition-based stats.
Identities = 14/70 (20%), Positives = 25/70 (36%), Gaps = 3/70 (4%)
Query 203 ALGKVTSDHINFDPVYK-VKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQY 261
+LG + + K P PP + V + + + LTW P Y ++
Sbjct 498 SLGNSRTTTLLRVKCVKHSPPGPP--VLVEMFKGQKNTVLLTWKPPEPPPETSFIYRLER 555
Query 262 RTKDASTWSQ 271
+ + W Q
Sbjct 556 QEVGSEDWIQ 565
Score = 37.9 bits (86), Expect = 0.64, Method: Composition-based stats.
Identities = 16/93 (17%), Positives = 34/93 (37%), Gaps = 5/93 (5%)
Query 513 YLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNE--TAVNV 570
+K +PP V K KN +L W + FI Y + + + + ++
Sbjct 512 CVKHSPPGPPVLVEMFKGQKNTVLLTWKPPEPPPETSFI--YRLERQEVGSEDWIQCFSI 569
Query 571 D-SSHTEYTLSSLTSDTLYMVRMAAYTDEGGKD 602
+ + E + ++ Y R+ ++ G
Sbjct 570 EKAGAVEVPGDCVPTEGDYRFRICTVSEHGRSP 602
>sp|Q9UJV3|TRIM1_HUMAN Probable E3 ubiquitin-protein ligase MID2
OS=Homo sapiens OX=9606 GN=MID2 PE=1 SV=3
Length=735
Score = 41.4 bits (95), Expect = 0.040, Method: Composition-based stats.
Identities = 25/143 (17%), Positives = 42/143 (29%), Gaps = 44/143 (31%)
Query 216 PVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYR---------TKDA 266
Y PNPP + + + + + W S I Y +QY +K
Sbjct 396 LDYLTAPNPPSIREELCTASHDT-ITVHWI--SDDEFSISSYELQYTIFTGQANFISKSW 452
Query 267 STWSQIPPED----------------------------TASTRSSFTVQDLKPFTEYVFR 298
+W P ++ +TV L+ T Y+F
Sbjct 453 CSWGLWPEIRKCKEAVSCSRLAGAPRGLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFI 512
Query 299 IRCMKEDGKGYWSDWSEEASGIT 321
++ + + G S SE T
Sbjct 513 VKAINQAG----SRNSEPTRLKT 531
Score = 38.3 bits (87), Expect = 0.36, Method: Composition-based stats.
Identities = 9/43 (21%), Positives = 16/43 (37%), Gaps = 0/43 (0%)
Query 568 VNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
+ + YT+ L S T Y+ + A G ++ T
Sbjct 489 IVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKT 531
Score = 36.8 bits (83), Expect = 1.1, Method: Composition-based stats.
Identities = 11/65 (17%), Positives = 18/65 (28%), Gaps = 0/65 (0%)
Query 466 CITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTV 525
+ W Y L Y+ V + G + E + P P +
Sbjct 483 SVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDPKM 542
Query 526 RTKKV 530
KK+
Sbjct 543 THKKL 547
>sp|P87061|TEA1_SCHPO Tip elongation aberrant protein 1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=tea1
PE=1 SV=1
Length=1147
Score = 41.8 bits (96), Expect = 0.040, Method: Composition-based stats.
Identities = 47/224 (21%), Positives = 70/224 (31%), Gaps = 16/224 (7%)
Query 632 TTLLGVLFCFNKRDLIKKHI--WPNVPDPSKSHIAQWSPHTP-----PRHNFNSKDQMYS 684
T L L+ F + P P P SH S T + S +Y
Sbjct 315 GTFLNDLYAFRLSSKHWYKLSDLPFTPSPRSSHTLSCSGLTLVLIGGKQGKGASDSNVYM 374
Query 685 DGN----FTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPS 740
V + F + + + T GS S+S PS
Sbjct 375 LDTSRFRLGSVPTTSGRQRNTSFFSNSTGNTNPSAFNGLLTSSRIPSYNGSKVRSTSHPS 434
Query 741 ISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSEST---QPLLDSEERPEDLQ 797
+ +S+ + ST V + +PS V +RS S+ QP + D +
Sbjct 435 RQQYIGSSNSRFNTRHQTISTPVSGRASNDLPSPVVPTRSNSSSILQPSYNLNSHSSDRR 494
Query 798 LVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVN 841
+ D L QQ Q +Q E SP +S S + N
Sbjct 495 --NTNDDDQSSLNSQQLSNQAKAQGEVSPTLSFVPSSHSMEQGN 536
>sp|Q28516|INSR_MACMU Insulin receptor (Fragment) OS=Macaca mulatta
OX=9544 GN=INSR PE=3 SV=1
Length=210
Score = 40.2 bits (92), Expect = 0.041, Method: Composition-based stats.
Identities = 11/54 (20%), Positives = 20/54 (37%), Gaps = 2/54 (4%)
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSS 581
++ +L+W P NG I +Y +F+ + +D L S
Sbjct 1 VSNSSSQIILKWK--PPSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPS 52
>sp|P0C7U0|ELFN1_HUMAN Protein ELFN1 OS=Homo sapiens OX=9606 GN=ELFN1
PE=1 SV=2
Length=828
Score = 41.4 bits (95), Expect = 0.045, Method: Composition-based stats.
Identities = 31/265 (12%), Positives = 77/265 (29%), Gaps = 19/265 (7%)
Query 503 GPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTII 562
G G+ + P ++ K++ +N A + + YT+ +
Sbjct 297 GDGTTPLVALPTLATQAEARPLIKVKQLTQNSATITVQLPSPFHRM-----YTLEHFNNS 351
Query 563 GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE--- 619
T + + E L++L + T Y + + + + T P+
Sbjct 352 KASTVSRLTKAQEEIRLTNLFTLTNYTYCVVSTSAGLRHNHTCLTICLPRLPSPPGPVPS 411
Query 620 -------AIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPP 672
+ + CL ++ L V +C +R ++ S +
Sbjct 412 PSTATHYIMTILGCLFGMVLVLGAVYYCLRRRRRQEEKHKKAA---SAAAAGSLKKTIIE 468
Query 673 RHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSS 732
+ + ++ EA + P+ ++ +K + +S
Sbjct 469 LKYGPELE-APGLAPLSQGPLLGPEAVTRIPYLPAAGEVEQYKLVESADTPKASKGSYME 527
Query 733 CMSSSRPSISSSDENESSQNTSSTV 757
+ P + ++ S+V
Sbjct 528 VRTGDPPERRDCELGRPGPDSQSSV 552
>sp|Q5NDE3|PMGT2_TETNG Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase
2 OS=Tetraodon nigroviridis OX=99883
GN=pomgnt2 PE=2 SV=1
Length=579
Score = 41.4 bits (95), Expect = 0.047, Method: Composition-based stats.
Identities = 22/79 (28%), Positives = 38/79 (48%), Gaps = 12/79 (15%)
Query 240 LKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST----RSSFTVQD-LKPFTE 294
L ++W P LKY ++ R W Q E+T + ++T D +KPFT
Sbjct 501 LTVSWQMP-----WNLKY-LKVREVKYEVWIQEQGENTYMPYILPQQNYTFSDNIKPFTT 554
Query 295 YVFRIRCM-KEDGKGYWSD 312
Y+ +RC+ ++ G ++D
Sbjct 555 YLVWVRCIFNKNLLGPFAD 573
>sp|Q66H07|FANK1_RAT Fibronectin type 3 and ankyrin repeat domains
1 protein OS=Rattus norvegicus OX=10116 GN=Fank1 PE=2 SV=1
Length=344
Score = 40.2 bits (92), Expect = 0.063, Method: Composition-based stats.
Identities = 20/115 (17%), Positives = 34/115 (30%), Gaps = 8/115 (7%)
Query 515 KQAPPSKGPTVRTK-KVGKNEAVLEWDQLPVDVQNGFIRNY-TIFYRTIIG--NETAVNV 570
K+ P P KV + L WD + + G + + V
Sbjct 4 KKIVPLLRPHPPVVGKVTHHSIELYWDLEKREKRQGPQEQWLRFSIEEEDPKMHNYGVIY 63
Query 571 DSSHTEYTLSSLTSDTLYMVRMAAYTDEG----GKDGPEFTFTTPKFAQGEIEAI 621
T++ + L TLY R+ + G T P ++ A+
Sbjct 64 TGYATKHVVEGLEPRTLYRFRLKVTSPSGEYEYSPVVSVATTREPISSEHFHRAV 118
Score = 40.2 bits (92), Expect = 0.069, Method: Composition-based stats.
Identities = 19/122 (16%), Positives = 44/122 (36%), Gaps = 10/122 (8%)
Query 221 KPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYN-IQYRTKDASTWSQIPPEDTAS 279
+P+PP V + ++L W + + +++ ++
Sbjct 11 RPHPPVVGKVTHH-----SIELYWDLEKREKRQGPQEQWLRFSIEEEDPKMHNYGVIYTG 65
Query 280 TRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPS 339
+ V+ L+P T Y FR++ G+ ++S S T + P + F ++ +
Sbjct 66 YATKHVVEGLEPRTLYRFRLKVTSPSGEY---EYSPVVSVATTRE-PISSEHFHRAVNVN 121
Query 340 HT 341
Sbjct 122 DE 123
>sp|Q2TLZ5|MACOI_PANTR Macoilin OS=Pan troglodytes OX=9598 GN=MACO1
PE=2 SV=1
Length=664
Score = 40.6 bits (93), Expect = 0.067, Method: Composition-based stats.
Identities = 37/223 (17%), Positives = 82/223 (37%), Gaps = 27/223 (12%)
Query 658 PSKSHIAQWSPHTPPRHNFNSKDQ---------------MYSDGNFTDVSVVEIEANDKK 702
P+ ++ P R KD+ D ++ +E N K+
Sbjct 238 PANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKR 297
Query 703 PFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTV 762
+ + S + KE T + S ++SS S S+++ + S ++ + +
Sbjct 298 LNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCT 357
Query 763 VHSGYRHQ------VPSVQVFSRSESTQPL-LDSEERPEDLQLVDHVDGGDGILPRQQYF 815
S H+ +P+ S+ ++ L D ++ DLQ V+ + R Q
Sbjct 358 SKSPSTHKDLMENCIPN-NQLSKPDALVRLEQDIKKLKADLQASRQVE--QEL--RSQIS 412
Query 816 KQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQ 858
+ ++ ++ + ++ + V++KQ+ +ISQ
Sbjct 413 SLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQ 455
>sp|Q8N5G2|MACOI_HUMAN Macoilin OS=Homo sapiens OX=9606 GN=MACO1
PE=1 SV=1
Length=664
Score = 40.6 bits (93), Expect = 0.067, Method: Composition-based stats.
Identities = 37/223 (17%), Positives = 82/223 (37%), Gaps = 27/223 (12%)
Query 658 PSKSHIAQWSPHTPPRHNFNSKDQ---------------MYSDGNFTDVSVVEIEANDKK 702
P+ ++ P R KD+ D ++ +E N K+
Sbjct 238 PANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKR 297
Query 703 PFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTV 762
+ + S + KE T + S ++SS S S+++ + S ++ + +
Sbjct 298 LNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCT 357
Query 763 VHSGYRHQ------VPSVQVFSRSESTQPL-LDSEERPEDLQLVDHVDGGDGILPRQQYF 815
S H+ +P+ S+ ++ L D ++ DLQ V+ + R Q
Sbjct 358 SKSPSTHKDLMENCIPN-NQLSKPDALVRLEQDIKKLKADLQASRQVE--QEL--RSQIS 412
Query 816 KQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQ 858
+ ++ ++ + ++ + V++KQ+ +ISQ
Sbjct 413 SLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQ 455
>sp|Q2TLZ1|MACOI_CANLF Macoilin OS=Canis lupus familiaris OX=9615
GN=MACO1 PE=2 SV=1
Length=664
Score = 40.6 bits (93), Expect = 0.067, Method: Composition-based stats.
Identities = 37/223 (17%), Positives = 82/223 (37%), Gaps = 27/223 (12%)
Query 658 PSKSHIAQWSPHTPPRHNFNSKDQ---------------MYSDGNFTDVSVVEIEANDKK 702
P+ ++ P R KD+ D ++ +E N K+
Sbjct 238 PANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKR 297
Query 703 PFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTV 762
+ + S + KE T + S ++SS S S+++ + S ++ + +
Sbjct 298 LNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCT 357
Query 763 VHSGYRHQ------VPSVQVFSRSESTQPL-LDSEERPEDLQLVDHVDGGDGILPRQQYF 815
S H+ +P+ S+ ++ L D ++ DLQ V+ + R Q
Sbjct 358 SKSPSTHKDLMENCIPN-NQLSKPDALVRLEQDIKKLKADLQASRQVE--QEL--RSQIS 412
Query 816 KQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQ 858
+ ++ ++ + ++ + V++KQ+ +ISQ
Sbjct 413 SLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQ 455
>sp|Q5NDF0|PMGT2_RAT Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase
2 OS=Rattus norvegicus OX=10116 GN=Pomgnt2
PE=1 SV=1
Length=580
Score = 40.6 bits (93), Expect = 0.068, Method: Composition-based stats.
Identities = 34/188 (18%), Positives = 64/188 (34%), Gaps = 43/188 (23%)
Query 146 WDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
WD G THL+ + +++ C + ++ + + V
Sbjct 409 WDQGGITHLD---------RAEQARILQSREVPRHLCCRNPEWLFRIYQDTRV------- 452
Query 206 KVTSDHINFDPVYKVKPNP----------PHNLS-----VINSEELSSILKLTWTNPSIK 250
+ S + V K +P P P + + L ++W P
Sbjct 453 DIPSLMQSIRRVVKGRPGPRRQRWAISLYPGKVREARCQASVQGATEARLSVSWQIP--- 509
Query 251 SVIILKYNIQYRTKDASTWSQIPPEDTAST-----RSSFTVQDLKPFTEYVFRIRCM-KE 304
LKY ++ R W Q E+T ++ +++KPFT Y+ +RC+
Sbjct 510 --WNLKY-LKVREVRYEVWLQEQGENTYVPYMLTLQNHTFTENIKPFTTYLVWVRCIFNR 566
Query 305 DGKGYWSD 312
G ++D
Sbjct 567 SLLGPFAD 574
>sp|Q2TLZ2|MACOI_PIG Macoilin OS=Sus scrofa OX=9823 GN=MACO1 PE=2
SV=1
Length=664
Score = 40.6 bits (93), Expect = 0.073, Method: Composition-based stats.
Identities = 37/223 (17%), Positives = 82/223 (37%), Gaps = 27/223 (12%)
Query 658 PSKSHIAQWSPHTPPRHNFNSKDQ---------------MYSDGNFTDVSVVEIEANDKK 702
P+ ++ P R KD+ D ++ +E N K+
Sbjct 238 PANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKR 297
Query 703 PFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTV 762
+ + S + KE T + S ++SS S S+++ + S ++ + +
Sbjct 298 LNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCT 357
Query 763 VHSGYRHQ------VPSVQVFSRSESTQPL-LDSEERPEDLQLVDHVDGGDGILPRQQYF 815
S H+ +P+ S+ ++ L D ++ DLQ V+ + R Q
Sbjct 358 SKSPSAHKDLMENCIPN-NQLSKPDALVRLEQDIKKLKADLQASRQVE--QEL--RSQIS 412
Query 816 KQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQ 858
+ ++ ++ + ++ + V++KQ+ +ISQ
Sbjct 413 SLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQ 455
>sp|Q2TLZ3|MACOI_BOVIN Macoilin OS=Bos taurus OX=9913 GN=MACO1
PE=2 SV=1
Length=664
Score = 40.6 bits (93), Expect = 0.073, Method: Composition-based stats.
Identities = 37/223 (17%), Positives = 82/223 (37%), Gaps = 27/223 (12%)
Query 658 PSKSHIAQWSPHTPPRHNFNSKDQ---------------MYSDGNFTDVSVVEIEANDKK 702
P+ ++ P R KD+ D ++ +E N K+
Sbjct 238 PANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKR 297
Query 703 PFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTV 762
+ + S + KE T + S ++SS S S+++ + S ++ + +
Sbjct 298 LNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCT 357
Query 763 VHSGYRHQ------VPSVQVFSRSESTQPL-LDSEERPEDLQLVDHVDGGDGILPRQQYF 815
S H+ +P+ S+ ++ L D ++ DLQ V+ + R Q
Sbjct 358 SKSPSAHKDLMENCIPN-NQLSKPDALVRLEQDIKKLKADLQASRQVE--QEL--RSQIS 412
Query 816 KQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQ 858
+ ++ ++ + ++ + V++KQ+ +ISQ
Sbjct 413 SLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKQNISQ 455
>sp|Q6PJG9|LRFN4_HUMAN Leucine-rich repeat and fibronectin type-III
domain-containing protein 4 OS=Homo sapiens OX=9606 GN=LRFN4
PE=1 SV=1
Length=635
Score = 40.6 bits (93), Expect = 0.078, Method: Composition-based stats.
Identities = 21/122 (17%), Positives = 35/122 (29%), Gaps = 16/122 (13%)
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA------VNVDSSHTE 576
P V+ +V ++ W ++ I N + V +S
Sbjct 407 PAVQVTEVTATSGLVSWGPGRPADP--------VWMFQIQYNSSEDETLIYRIVPASSHH 458
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLG 636
+ L L Y + + A + G + T T P+C A L G
Sbjct 459 FLLKHLVPGADYDLCLLALSPAAGP--SDLTATRLLGCAHFSTLPASPLCHALQAHVLGG 516
Query 637 VL 638
L
Sbjct 517 TL 518
>sp|P11220|CHIT_STRPL Chitinase 63 OS=Streptomyces plicatus OX=1922
GN=chtA PE=1 SV=2
Length=610
Score = 40.6 bits (93), Expect = 0.078, Method: Composition-based stats.
Identities = 33/183 (18%), Positives = 48/183 (26%), Gaps = 27/183 (15%)
Query 431 KAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESK 490
WT + + + W ++ + G LA
Sbjct 53 TVKNTGTTSLSSWTVEWDFPSGTKVTSAWDATVTNSADHWTAKNVGWN-----GTLAPGA 107
Query 491 CYLITVTPVYADGPGSPE--SIKAYL-------KQAPPSKGPTVRTKKVGKNEAVLEWDQ 541
GPGSP I PS T + L W
Sbjct 108 SVSF---GFNGSGPGSPSGCKINGGSCDGSSVPGDEAPSAPGTPTASNITDTSVKLSWSA 164
Query 542 LPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGK 601
D ++NY + + A + T YT + LT T Y + A D G +
Sbjct 165 ATDDKG---VKNYDVL------RDGATVATVTGTTYTDNGLTKGTDYSYSVKAR-DTGDQ 214
Query 602 DGP 604
GP
Sbjct 215 TGP 217
>sp|Q2TLZ4|MACOI_MACMU Macoilin OS=Macaca mulatta OX=9544 GN=MACO1
PE=2 SV=1
Length=664
Score = 40.2 bits (92), Expect = 0.086, Method: Composition-based stats.
Identities = 37/223 (17%), Positives = 82/223 (37%), Gaps = 27/223 (12%)
Query 658 PSKSHIAQWSPHTPPRHNFNSKDQ---------------MYSDGNFTDVSVVEIEANDKK 702
P+ ++ P R KD+ D ++ +E N K+
Sbjct 238 PANKKLSTTLPEIEYREKGKEKDKDAKKHNLGINNNNILQPVDSKIQEIEYMENHINSKR 297
Query 703 PFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTV 762
+ + S + KE T + S ++SS S S+++ + S ++ + +
Sbjct 298 LNNDLVGSTENLLKEDSCTASSKNYKNASGVVNSSPRSHSATNGSIPSSSSKNEKKQKCT 357
Query 763 VHSGYRHQ------VPSVQVFSRSESTQPL-LDSEERPEDLQLVDHVDGGDGILPRQQYF 815
S H+ +P+ S+ ++ L D ++ DLQ V+ + R Q
Sbjct 358 SKSPSTHKDLMENCIPN-NQLSKPDALVRLEQDIKKLKADLQASRQVE--QEL--RSQIS 412
Query 816 KQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQ 858
+ ++ ++ + ++ + V++KQ+ +ISQ
Sbjct 413 SLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDKHNISQ 455
>sp|Q5NDE4|PMGT2_TAKRU Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase
2 OS=Takifugu rubripes OX=31033 GN=pomgnt2
PE=2 SV=1
Length=590
Score = 40.2 bits (92), Expect = 0.089, Method: Composition-based stats.
Identities = 22/85 (26%), Positives = 39/85 (46%), Gaps = 12/85 (14%)
Query 234 EELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTAST----RSSFTVQD- 288
+ L ++W P LKY ++ R W Q E+T + ++T D
Sbjct 506 TSNEAKLTVSWQIP-----WNLKY-LKVREVKYEVWIQEQGENTYMPYILPQQNYTFSDN 559
Query 289 LKPFTEYVFRIRCM-KEDGKGYWSD 312
+KPFT Y+ +RC+ ++ G ++D
Sbjct 560 IKPFTTYLVWVRCIFNKNLLGPFAD 584
Score = 38.7 bits (88), Expect = 0.29, Method: Composition-based stats.
Identities = 16/105 (15%), Positives = 35/105 (33%), Gaps = 5/105 (5%)
Query 400 LTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRES--VKKYILEW 457
+ + L+ KS + P + ++ + L V W P +K +++
Sbjct 475 VKAKPLLKKSKLSSTLHPGR-VRDPQCQTSVQ-TSNEAKLTVSWQIPWNLKYLKVREVKY 532
Query 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYAD 502
V + T + T+ N+ YL+ V ++
Sbjct 533 EVWIQEQGENTYMPYILPQQNYTF-SDNIKPFTTYLVWVRCIFNK 576
>sp|Q8N6P7|I22R1_HUMAN Interleukin-22 receptor subunit alpha-1
OS=Homo sapiens OX=9606 GN=IL22RA1 PE=1 SV=1
Length=574
Score = 40.2 bits (92), Expect = 0.094, Method: Composition-based stats.
Identities = 28/198 (14%), Positives = 65/198 (33%), Gaps = 24/198 (12%)
Query 114 NVYGITIISGLPPEKP----KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHK- 168
+ + ++ PE P +++ + + + WD G E +T ++++ + +
Sbjct 6 TILTVGSLAAHAPEDPSDLLQHVKFQSSNFENI-LTWDSGPEGTPDTVYSIEYKTYGERD 64
Query 169 ------FADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN-FDPVYKVK 221
K T T + + +Y+ V A +A G+ + + F +
Sbjct 65 WVAKKGCQRITRKSCNLTVETGNLTELYYA----RVTAVSAGGRSATKMTDRFSSLQHTT 120
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILK-----YNIQYRTKDASTWSQIPPED 276
PP + + I+ T T L +++ Y + ++
Sbjct 121 LKPPDVTCISKVRSIQMIVHPTPTPIRAGDGHRLTLEDIFHDLFYHLE--LQVNRTYQMH 178
Query 277 TASTRSSFTVQDLKPFTE 294
+ + L P TE
Sbjct 179 LGGKQREYEFFGLTPDTE 196
>sp|Q32L96|PHIPL_BOVIN Phytanoyl-CoA hydroxylase interacting protein-like
OS=Bos taurus OX=9913 GN=PHYHIPL PE=2 SV=2
Length=376
Score = 39.8 bits (91), Expect = 0.094, Method: Composition-based stats.
Identities = 24/110 (22%), Positives = 39/110 (35%), Gaps = 11/110 (10%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS-- 282
P ++ S K++W S I Y I K+ ++ +D +
Sbjct 51 PVPRNIKISNITCDSFKISWEMDSKSKDRITHYFIDLNKKENKNSNKFKHKDVPTKLVAK 110
Query 283 ----SFTVQD---LKPFTEYVFRIR--CMKEDGKGYWSDWSEEASGITYE 323
TV+ L P TEY ++ + DG S+WSE T +
Sbjct 111 AVPLPMTVRGHWFLSPRTEYTVAVQTASKQVDGDYVVSEWSEIIEFCTAD 160
>sp|D4ABX8|LRFN4_RAT Leucine-rich repeat and fibronectin type-III
domain-containing protein 4 OS=Rattus norvegicus OX=10116
GN=Lrfn4 PE=1 SV=1
Length=636
Score = 40.2 bits (92), Expect = 0.095, Method: Composition-based stats.
Identities = 21/122 (17%), Positives = 35/122 (29%), Gaps = 16/122 (13%)
Query 523 PTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETA------VNVDSSHTE 576
P V+ +V ++ W ++ I N + V +S
Sbjct 407 PAVQVTEVTATSGLVSWGPGRPADP--------VWMFQIQYNSSEDETLIYRIVPASSQH 458
Query 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLG 636
+ L L Y + + A + G + T T P+C A L G
Sbjct 459 FLLKHLVPGADYDLCLLALSPAAGP--SDLTATRLLGCAHFSTLPATPLCHALQAHVLGG 516
Query 637 VL 638
L
Sbjct 517 TL 518
>sp|O35664|INAR2_MOUSE Interferon alpha/beta receptor 2 OS=Mus
musculus OX=10090 GN=Ifnar2 PE=1 SV=2
Length=513
Score = 40.2 bits (92), Expect = 0.095, Method: Composition-based stats.
Identities = 32/182 (18%), Positives = 62/182 (34%), Gaps = 15/182 (8%)
Query 126 PEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSE--WATHKFADCKAKRDTPTSCT 183
P++P ++ + + + W+ ++ N+TL K DT S
Sbjct 35 PDEPCTINITIRNSR-LILSWELENKSGPPANYTLWYTVMSKDENLTKVKNCSDTTKSSC 93
Query 184 V--DYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILK 241
D + V + + G +T + Y V N P + +
Sbjct 94 DVTDKWLEGMESYVVAIVIVHR-GDLT---VCRCSDYIVPANAPLEPPEFEIVGFTDHIN 149
Query 242 LTWTNPSIKSVIILK------YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEY 295
+T P + S II + + I+ + D+ P + + +F ++DL P T Y
Sbjct 150 VTMEFPPVTSKIIQEKMKTTPFVIKEQIGDSVRKKHEPKVNNVTGNFTFVLRDLLPKTNY 209
Query 296 VF 297
Sbjct 210 CV 211
>sp|O74161|CHS5_CANAL Chitin biosynthesis protein CHS5 OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=CHS5
PE=3 SV=2
Length=562
Score = 40.2 bits (92), Expect = 0.098, Method: Composition-based stats.
Identities = 20/91 (22%), Positives = 33/91 (36%), Gaps = 4/91 (4%)
Query 520 SKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTL 579
+ P ++ K V + VLEWD+L G + ++ ++ L
Sbjct 77 PQPPNLKIKNVTQTSCVLEWDKL----NLGTATLKNLILFKDGKKLGSIPQPLNNRTSKL 132
Query 580 SSLTSDTLYMVRMAAYTDEGGKDGPEFTFTT 610
S L D + V++ T G E TT
Sbjct 133 SGLPIDKSFKVQLRLDTTAGTFLSNEIEVTT 163
>sp|P11912|CD79A_HUMAN B-cell antigen receptor complex-associated
protein alpha chain OS=Homo sapiens OX=9606 GN=CD79A PE=1
SV=2
Length=226
Score = 39.1 bits (89), Expect = 0.10, Method: Composition-based stats.
Identities = 21/127 (17%), Positives = 37/127 (29%), Gaps = 15/127 (12%)
Query 11 ALFIFLTTESTGELLDPCG----YISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIV 66
A L S L C + P S +V L + C + N +
Sbjct 13 ATIFLLFLLSAVYLGPGCQALWMHKVPASLMVSLGEDAHFQC-------PHNSSNNANVT 65
Query 67 WKT---NHFTIPKEQYTIINRTASSVTFTDIASLNI-QLTCNILTFGQLEQNVYGITIIS 122
W ++T P E ++ ++ + C + + Q G +
Sbjct 66 WWRVLHGNYTWPPEFLGPGEDPNGTLIIQNVNKSHGGIYVCRVQEGNESYQQSCGTYLRV 125
Query 123 GLPPEKP 129
PP +P
Sbjct 126 RQPPPRP 132
>sp|Q7TNI4|I22R2_RAT Interleukin-22 receptor subunit alpha-2 OS=Rattus
norvegicus OX=10116 GN=Il22ra2 PE=2 SV=1
Length=229
Score = 39.1 bits (89), Expect = 0.11, Method: Composition-based stats.
Identities = 24/135 (18%), Positives = 42/135 (31%), Gaps = 12/135 (9%)
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWS-QIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
L W + + Y +QY+T W + T + T + L P+ Y R+
Sbjct 43 LHWQPGNSLTSNGSVYFVQYKTYGQGQWKDKNDCWGTTALFCDLTKETLDPYEPYYGRVM 102
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
G +S+W+ + + P + + V+L LP
Sbjct 103 ---MAWAGSYSEWTRTPRFTPWWETKLDPP----VVTITRVNASLRVRLRPPELPHRNQT 155
Query 361 GKILD----YEVTLT 371
GK Y +
Sbjct 156 GKNTSMENYYNLVYR 170
>sp|P43432|IL12B_MOUSE Interleukin-12 subunit beta OS=Mus musculus
OX=10090 GN=Il12b PE=1 SV=1
Length=335
Score = 39.5 bits (90), Expect = 0.11, Method: Composition-based stats.
Identities = 28/148 (19%), Positives = 50/148 (34%), Gaps = 21/148 (14%)
Query 132 LSCIVNEGKK-MRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDT------------ 178
L C C W R L+ N S + C +
Sbjct 126 LKCEAPNYSGRFTCSWLVQRNMDLKFNIKSSSSSPDSRAVTCGMASLSAEKVTLDQRDYE 185
Query 179 --PTSCTVD---YSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINS 233
SC D + + IE+ +EA K + +F +KP+PP NL +
Sbjct 186 KYSVSCQEDVTCPTAEETLPIELALEARQQN-KYENYSTSFFIRDIIKPDPPKNLQMK-- 242
Query 234 EELSSILKLTWTNPSIKSVIILKYNIQY 261
+S ++++W P S +++++
Sbjct 243 PLKNSQVEVSWEYPDSWSTPHSYFSLKF 270
>sp|Q6VNS1|NTRK3_MOUSE NT-3 growth factor receptor OS=Mus musculus
OX=10090 GN=Ntrk3 PE=1 SV=1
Length=825
Score = 40.2 bits (92), Expect = 0.11, Method: Composition-based stats.
Identities = 36/224 (16%), Positives = 66/224 (29%), Gaps = 38/224 (17%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
V+ N C + + W T +N T +V ++
Sbjct 220 TVREGDNAVITC-------NGSGSPLPDVDWIVTGLQSINTHQTNLNWT--NVHAINLTL 270
Query 97 LNIQLTCNILTFGQLEQNVYG-----ITIISGLPPEKPKNLSCIVNEGK-----KMRCEW 146
+N+ N T + +NV G + + P P+ +S + E + +
Sbjct 271 VNVTSEDNGFTLTCIAENVVGMSNASVALTVYYP---PRVVSLVEPEVRLEHCIEFVVRG 327
Query 147 DGGRETH-LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
+ H L L+ H D + + C + ++ N + A+NALG
Sbjct 328 NPTPTLHWLYNGQPLRESKIIH--MDYYQEGEVSEGCLLFNKPTHYNNGNYTLIAKNALG 385
Query 206 KV-------------TSDHINFDPVYKVKPNPPHNLSVINSEEL 236
FD P PP ++ E+
Sbjct 386 TANQTINGHFLKEPFPESTDFFDFESDASPTPPITVTHKPEEDT 429
>sp|Q03351|NTRK3_RAT NT-3 growth factor receptor OS=Rattus norvegicus
OX=10116 GN=Ntrk3 PE=1 SV=2
Length=864
Score = 40.2 bits (92), Expect = 0.11, Method: Composition-based stats.
Identities = 36/224 (16%), Positives = 66/224 (29%), Gaps = 38/224 (17%)
Query 37 VVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIAS 96
V+ N C + + W T +N T +V ++
Sbjct 220 TVREGDNAVITC-------NGSGSPLPDVDWIVTGLQSINTHQTNLNWT--NVHAINLTL 270
Query 97 LNIQLTCNILTFGQLEQNVYG-----ITIISGLPPEKPKNLSCIVNEGK-----KMRCEW 146
+N+ N T + +NV G + + P P+ +S + E + +
Sbjct 271 VNVTSEDNGFTLTCIAENVVGMSNASVALTVYYP---PRVVSLVEPEVRLEHCIEFVVRG 327
Query 147 DGGRETH-LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALG 205
+ H L L+ H D + + C + ++ N + A+NALG
Sbjct 328 NPTPTLHWLYNGQPLRESKIIH--MDYYQEGEVSEGCLLFNKPTHYNNGNYTLIAKNALG 385
Query 206 KV-------------TSDHINFDPVYKVKPNPPHNLSVINSEEL 236
FD P PP ++ E+
Sbjct 386 TANQTINGHFLKEPFPESTDFFDFESDASPTPPITVTHKPEEDT 429
>sp|Q6B858|FANK1_BOVIN Fibronectin type 3 and ankyrin repeat domains
protein 1 OS=Bos taurus OX=9913 GN=FANK1 PE=2 SV=2
Length=345
Score = 39.5 bits (90), Expect = 0.12, Method: Composition-based stats.
Identities = 19/116 (16%), Positives = 34/116 (29%), Gaps = 8/116 (7%)
Query 514 LKQAPPSKGPTVRTK-KVGKNEAVLEWDQLPVDVQNGFIRN-YTIFYRTIIG--NETAVN 569
L++ S P KV + L WD + G + + +
Sbjct 3 LQKIASSSKPHPPVVGKVTHHSIELYWDLEKKAKRQGPQEQWFRFSIEEEDPKLHTYGII 62
Query 570 VDSSHTEYTLSSLTSDTLYMVRMAAYTDEG----GKDGPEFTFTTPKFAQGEIEAI 621
T++ + L TLY R+ + G T P ++ A+
Sbjct 63 YTGYATKHVVEGLEPRTLYRFRLKVTSPSGEYAYSPVVSVSTTREPISSEHLHRAV 118
>sp|Q80XF5|I22R2_MOUSE Interleukin-22 receptor subunit alpha-2
OS=Mus musculus OX=10090 GN=Il22ra2 PE=1 SV=2
Length=230
Score = 39.1 bits (89), Expect = 0.13, Method: Composition-based stats.
Identities = 23/120 (19%), Positives = 36/120 (30%), Gaps = 12/120 (10%)
Query 242 LTWTNPSIKSVIILKYNIQYRTKDASTWS-QIPPEDTASTRSSFTVQDLKPFTEYVFRIR 300
L W S Y +QY+ S W ++ T + T + L P+ Y R+
Sbjct 44 LHWQAGSSLPSNNSIYFVQYKMYGQSQWEDKVDCWGTTALFCDLTNETLDPYELYYGRVM 103
Query 301 CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN 360
G S W+ + + P + + V L PP N
Sbjct 104 TACA---GRHSAWTRTPRFTPWWETKLDPP----VVTITRVNASLRVLL----RPPELPN 152
>sp|B0CLX4|VSI10_DANRE V-set and immunoglobulin domain-containing
protein 10 OS=Danio rerio OX=7955 GN=vsig10 PE=2 SV=1
Length=529
Score = 39.5 bits (90), Expect = 0.14, Method: Composition-based stats.
Identities = 32/233 (14%), Positives = 68/233 (29%), Gaps = 18/233 (8%)
Query 38 VQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASL 97
V SN C + + + W ++ + +++ + + T+I L
Sbjct 140 VHKGSNVNFSCSSESN-------PSQNLTWTVDNLASDNPEREFGSKSPLAFSITNIQPL 192
Query 98 NIQ-LTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKK---MRCEWDGGRETH 153
+ TC ++ PE+ S + + C W GG
Sbjct 193 DQGTYTCTSQNTLSRRTANKTQELLVYYAPERHPECSWELGDKPSDVLFICSWFGGYPVP 252
Query 154 LETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHIN 213
T ++ +++ + +V+ ++ +V + G S
Sbjct 253 TLTWQEVEGAAEGPTINLTTSQQTEELNVSVN-RSILHDGDKVKCTGHHVTGVEKSCSFT 311
Query 214 FD-PVYKVKPNPP----HNLSVINSEELS-SILKLTWTNPSIKSVIILKYNIQ 260
P +P N+++ +E S K W KY +Q
Sbjct 312 LKIPYPTGQPLATALEGTNITISCTETSSLPPAKTVWKKNDDLIENTSKYIVQ 364
>sp|O82833|GELLY_BACSP Gellan lyase OS=Bacillus sp. OX=1409 PE=1
SV=1
Length=2475
Score = 39.8 bits (91), Expect = 0.16, Method: Composition-based stats.
Identities = 22/105 (21%), Positives = 38/105 (36%), Gaps = 12/105 (11%)
Query 215 DPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPP 274
+ + P P N+ V S + + ++WT S + IL Y + +
Sbjct 614 NRLDTENPTAPANVQVAISNTMQA--HVSWTASSDDTG-ILYYKV---------FRDGAL 661
Query 275 EDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 319
T + +SF L P TEY + ++ K S + S
Sbjct 662 VGTVTNATSFVDNGLAPATEYTYVVKAYDLVLKEAVSQPATATSP 706
>sp|C4JHZ6|M28P2_UNCRE Probable zinc metalloprotease UREG_01421
OS=Uncinocarpus reesii (strain UAMH 1704) OX=336963 GN=UREG_01421
PE=3 SV=1
Length=503
Score = 39.5 bits (90), Expect = 0.16, Method: Composition-based stats.
Identities = 20/85 (24%), Positives = 32/85 (38%), Gaps = 6/85 (7%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P P N+ V + + K W P + + Y I +R+ A W+ +
Sbjct 414 PGMPRNVRVSTRDLSNDS-KFFWDPPVGGNEGVGGYEIVWRSTVAPFWTHVLD---VGMA 469
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDG 306
TV DL +F IR ++G
Sbjct 470 REATV-DLSKDNV-IFGIRARGKNG 492
>sp|A4QNW7|PHIPL_DANRE Phytanoyl-CoA hydroxylase-interacting protein-like
OS=Danio rerio OX=7955 GN=phyhipl PE=2 SV=1
Length=377
Score = 39.1 bits (89), Expect = 0.17, Method: Composition-based stats.
Identities = 24/110 (22%), Positives = 39/110 (35%), Gaps = 11/110 (10%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS-- 282
P ++ S K+ W S I Y I K+ ++ +D +
Sbjct 51 PVPQNIKISNITCDSFKICWDMDSRSKERITHYFIDLNKKENKNANKFKHKDVPTKLVAK 110
Query 283 ----SFTVQD---LKPFTEYVFRIRCMKEDGKGYW--SDWSEEASGITYE 323
TV+ L P TEY ++ + G G + S+WSE T +
Sbjct 111 AVPLPMTVRGHWFLSPRTEYTVAVQTASKQGDGDYAVSEWSEINEFCTAD 160
>sp|Q9LKI5|XPF_ARATH DNA repair endonuclease UVH1 OS=Arabidopsis
thaliana OX=3702 GN=UVH1 PE=1 SV=2
Length=956
Score = 39.5 bits (90), Expect = 0.17, Method: Composition-based stats.
Identities = 55/240 (23%), Positives = 91/240 (38%), Gaps = 20/240 (8%)
Query 688 FTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDEN 747
+ + N+ +P D S K +K T S + ++S+P I EN
Sbjct 513 LGKTTDMASGNNNPEP-HVDKASCTKGKAKKDPTSLRRSLRSCNKKTTNSKPEILPGPEN 571
Query 748 ESSQNTSSTV--QYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGG 805
E N +ST Q + V ++P F ES QP+LD +P + +V H D G
Sbjct 572 EEKANEASTSAPQEANAVRPSGAKKLP-PVHFYALESDQPILDI-LKPSVI-IVYHPDMG 628
Query 806 DGILPRQQYFKQNCSQ--------HESSPDISHFERSKQVSSVNEEDFVRLKQQISDHIS 857
+ + Y +N + ++ S ++ FE S + + E +R K + +
Sbjct 629 -FVRELEVYKAENPLRKLKVYFIFYDESTEVQKFEASIRRENEAFESLIRQKSSMIIPVD 687
Query 858 QS---CGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEGMPKSYLPQTVRQGG 914
Q GS F S ++ G+ E + + E M S LP + Q G
Sbjct 688 QDGLCMGSNSSTEFPASSTQNSLTRKAGGRKELEKETQVIVDMREFM--SSLPNVLHQKG 745
>sp|K9JA28|INLR1_CHICK Interferon lambda receptor 1 OS=Gallus
gallus OX=9031 GN=IFNLR1 PE=2 SV=1
Length=567
Score = 39.5 bits (90), Expect = 0.17, Method: Composition-based stats.
Identities = 43/281 (15%), Positives = 76/281 (27%), Gaps = 43/281 (15%)
Query 425 HPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED-------GTV 477
P ++ KD + + WT S + + V + + W + +
Sbjct 25 PPPQNVTLLSKDFDMILTWTPGEGSPPD--VLYTVRYESKTRMDKWIKVPHCRNIHSVSC 82
Query 478 HRTYLRGNLAESKCYLITVTPVYA--DGPGSPESIKAY---LKQAPPSKGPTVR-----T 527
+ T + N + V P K Y ++ APP V+
Sbjct 83 NLTCVIPNF--FIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHV 140
Query 528 KKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS-SHTEYTLSSLTSDT 586
+ + LP Y + T+ +
Sbjct 141 NATFPMAICV--ESLPWM--------YDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRG 190
Query 587 LYMVRMAAYTDEGGKDGPEFTFTTPK----FAQGEIEAI---VVPVCLAFLLTTLLGVLF 639
Y A + D F+ P +GE + +PV + +L T +++
Sbjct 191 NYCF--NARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIW 248
Query 640 CFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKD 680
+ KK P D S IA + R N D
Sbjct 249 LLKQDAKHKKM--PQTLDLSNCKIAGPTFCCELRENEFLTD 287
>sp|Q96FC7|PHIPL_HUMAN Phytanoyl-CoA hydroxylase-interacting protein-like
OS=Homo sapiens OX=9606 GN=PHYHIPL PE=1 SV=3
Length=376
Score = 39.1 bits (89), Expect = 0.18, Method: Composition-based stats.
Identities = 26/110 (24%), Positives = 41/110 (37%), Gaps = 13/110 (12%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS-- 282
PHN+ + N K++W S I Y I K+ ++ +D +
Sbjct 53 PHNIKISNI--TCDSFKISWEMDSKSKDRITHYFIDLNKKENKNSNKFKHKDVPTKLVAK 110
Query 283 ----SFTVQD---LKPFTEYVFRIR--CMKEDGKGYWSDWSEEASGITYE 323
TV+ L P TEY ++ + DG S+WSE T +
Sbjct 111 AVPLPMTVRGHWFLSPRTEYTVAVQTASKQVDGDYVVSEWSEIIEFCTAD 160
>sp|O43432|IF4G3_HUMAN Eukaryotic translation initiation factor
4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2
Length=1585
Score = 39.5 bits (90), Expect = 0.18, Method: Composition-based stats.
Identities = 44/246 (18%), Positives = 93/246 (38%), Gaps = 23/246 (9%)
Query 679 KDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSR 738
+ T +++ + S E +S + S +
Sbjct 1049 PSKFLKITKPTIDEKIQLVPKAQLGSWGKGSSGGAKASETDALRSSASSLNRFSALQPPA 1108
Query 739 PSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPS----VQVFSRSESTQPLLDS----E 790
PS S+ + + ++ +PS F R S++ LLD+ E
Sbjct 1109 PSGSTPSTPVEFDSRRTLTSRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLDNQSQEE 1168
Query 791 ERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQ 850
+R E L+ V + GG + ++N ++ + P+IS + ++++EE+ R +
Sbjct 1169 QRREMLETVKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDK-AALSEEELERKSK 1227
Query 851 QISD---HISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDE-GMPKSYL 906
I D HI+ M+ +E++A +G + F VG+E+ + + + ++
Sbjct 1228 SIIDEFLHIND--FKEAMQCVEELNA--------QGLLHVFVRVGVESTLERSQITRDHM 1277
Query 907 PQTVRQ 912
Q + Q
Sbjct 1278 GQLLYQ 1283
>sp|Q05793|PGBM_MOUSE Basement membrane-specific heparan sulfate
proteoglycan core protein OS=Mus musculus OX=10090 GN=Hspg2
PE=1 SV=1
Length=3707
Score = 39.5 bits (90), Expect = 0.19, Method: Composition-based stats.
Identities = 33/210 (16%), Positives = 63/210 (30%), Gaps = 22/210 (10%)
Query 31 ISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVT 90
I P S VQ + + C++ E M + WK + + N + ++
Sbjct 2348 IEPPSSTVQQGQDASFKCLIHEGAMPI------KVEWKIRDQELEDNVHISPNGSIITIV 2401
Query 91 FTDIASLNIQLTCNILTFGQLEQNVYGITII----SGLPPEKPKNLSCIVNEGKKMRCEW 146
+ C + Q+V +++ + PE P ++ + + + C
Sbjct 2402 APG-PATMEPTACVASNVYGMAQSVVNLSVHGPPTVSVLPEGPVHVK--MGKDITLEC-I 2457
Query 147 DGGRETHLE--TNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENAL 204
G T + + F + + +V +A+NAL
Sbjct 2458 SSGEPRSSPRWTRLGIPVKLEPRMFGLMNSHAMLKIASVKPSDAGTYVC-----QAQNAL 2512
Query 205 GKVTSDHINFDPVYKVKPNPPHNLSVINSE 234
G V P P + V SE
Sbjct 2513 GTAQKQVELIVDTGTVAPGTPQ-VQVEESE 2541
>sp|P31997|CEAM8_HUMAN Carcinoembryonic antigen-related cell adhesion
molecule 8 OS=Homo sapiens OX=9606 GN=CEACAM8 PE=1 SV=2
Length=349
Score = 39.1 bits (89), Expect = 0.19, Method: Composition-based stats.
Identities = 37/263 (14%), Positives = 71/263 (27%), Gaps = 29/263 (11%)
Query 313 WSEEASGI-TYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLT 371
W+ + T E PS A + H W +AN +I+ Y ++
Sbjct 28 WNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYNWYKGETVDANRRIIGYVISNQ 87
Query 372 -----RWKSHLQNYTVNATKLTVNLTND---RYLATLTVRNLVGKSDAAVLTIPACDFQA 423
S+ + NA+ L N+T + Y + NL+ + ++ +
Sbjct 88 QITPGPAYSNRETIYPNASLLMRNVTRNDTGSYTLQVIKLNLMSEEVTGQFSVHPETPKP 147
Query 424 THPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLR 483
+ + + + + W V P Q +G T L
Sbjct 148 SISSNNSNPVEDKDAVAFTCEP---ETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLS 204
Query 484 GNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGP-----------TVRTKKVGK 532
+ Y + + P ++ P+ P +
Sbjct 205 VTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHAASN 264
Query 533 NEAVLEWDQLPVDVQNGFIRNYT 555
+ W NG + YT
Sbjct 265 PPSQYSW------SVNGTFQQYT 281
>sp|Q0WYX8|MDGA1_CHICK MAM domain-containing glycosylphosphatidylinositol
anchor protein 1 OS=Gallus gallus OX=9031 GN=MDGA1
PE=1 SV=1
Length=949
Score = 39.5 bits (90), Expect = 0.21, Method: Composition-based stats.
Identities = 20/89 (22%), Positives = 30/89 (34%), Gaps = 8/89 (9%)
Query 521 KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHT----- 575
PT+ K+ +L+W Q D + I Y + R + T
Sbjct 638 PNPTLSQKQSKNYSYILQWTQKEPDAVD-PILKYRLEVRQLAQRNTIQTFIPVQKMEKGL 696
Query 576 --EYTLSSLTSDTLYMVRMAAYTDEGGKD 602
E+ L +L Y VR+ T G D
Sbjct 697 LLEHILPNLKVPQSYEVRLTPITSFGAGD 725
>sp|P18191|MBHL_AZOCH Uptake hydrogenase large subunit OS=Azotobacter
chroococcum mcd 1 OX=355 GN=hupL PE=3 SV=3
Length=601
Score = 39.1 bits (89), Expect = 0.21, Method: Composition-based stats.
Identities = 35/190 (18%), Positives = 60/190 (32%), Gaps = 33/190 (17%)
Query 226 HNLSVINSEELSSILKLT-WTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
N+ ++ S +K W +++ + +Y I YR+ Q+ A +S+
Sbjct 381 TNIKELDEAHKYSWIKARAWRGHAMEVGPLARYIIAYRSGREYVKEQVDRSLAAFNQSTG 440
Query 285 TVQDLK---PFT---------EYVFRI------------------RCMKEDGKGYWSDWS 314
LK P T E + R K S W
Sbjct 441 LNLGLKQFLPSTLGRTLARALECELAVDSMLDDWQALVGNIKAGDRATANVEKWDPSTWP 500
Query 315 EEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ-LVWKTLPPFEANGKILDYEVTLTRW 373
+EA G+ + P A W ++ + Y+ + W P + G I YE L
Sbjct 501 KEAKGVGINEAPRGALGHWIRLKDGKIENYQAIVPTTWNGTPR-DHLGNIGAYEAALLNT 559
Query 374 KSHLQNYTVN 383
+ + V
Sbjct 560 RMERPDEPVE 569
>sp|Q9SUM4|VIL2_ARATH VIN3-like protein 2 OS=Arabidopsis thaliana
OX=3702 GN=VIL2 PE=1 SV=1
Length=714
Score = 39.1 bits (89), Expect = 0.22, Method: Composition-based stats.
Identities = 15/77 (19%), Positives = 29/77 (38%), Gaps = 3/77 (4%)
Query 228 LSVINSEELSSILKL-TWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 286
+ + S + L + PS + I+ Y+I +R + + + F V
Sbjct 370 IRFEDVNATSLTVVLASNEIPSPPN--IVHYSIWHRKVPEKDYPEKSTCTLFIPNTRFVV 427
Query 287 QDLKPFTEYVFRIRCMK 303
L P +EY F++
Sbjct 428 SGLAPASEYCFKVVSYS 444
>sp|Q80WB0|FND11_MOUSE Fibronectin type III domain-containing
protein 11 OS=Mus musculus OX=10090 GN=Fndc11 PE=1 SV=1
Length=326
Score = 38.7 bits (88), Expect = 0.23, Method: Composition-based stats.
Identities = 18/106 (17%), Positives = 35/106 (33%), Gaps = 3/106 (3%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS-S 283
P S + L W +I+ +Y ++++ + T + + +
Sbjct 212 PVMFDRKESVAHQDWVSLRWFV-TIQPAAPEQYELRFKLLEPRTQQECTQCGIVPVAACT 270
Query 284 FTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKA 329
F V +L P Y F I+ E + W + + T P
Sbjct 271 FDVHNLLPNRTYKFTIK-RAESYTLVYEPWRDSLTLQTTPGPPEGP 315
>sp|Q96RW7|HMCN1_HUMAN Hemicentin-1 OS=Homo sapiens OX=9606 GN=HMCN1
PE=1 SV=2
Length=5635
Score = 39.5 bits (90), Expect = 0.24, Method: Composition-based stats.
Identities = 27/239 (11%), Positives = 65/239 (27%), Gaps = 39/239 (16%)
Query 33 PESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFT 92
P +V + + C ++ + + W + + K + I +
Sbjct 2299 PTEIIVTRGKSISLECEVQ-------GIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLK 2351
Query 93 DIASLNI-QLTCNILTFGQLEQNVYGITIISGLPPEK------PKNLSCIVNEGKKMRC- 144
+I + + C + + Y + PP P+N+S + + C
Sbjct 2352 NIHVSDTGRYVCVAVNVAGMTDKKY--DLSVHAPPSIIGNHRSPENISVVEKNSVSLTCE 2409
Query 145 ---------EW-DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVD---YSTVYF 191
W G L + + S + + +C V
Sbjct 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKI 2469
Query 192 VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIK 250
+ V V + + + VK ++++ + + ++TW
Sbjct 2470 FGLSVLV---------PPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQP 2519
>sp|B0S6J3|SRGP2_DANRE SLIT-ROBO Rho GTPase-activating protein
2 OS=Danio rerio OX=7955 GN=srgap2 PE=2 SV=1
Length=1100
Score = 38.7 bits (88), Expect = 0.28, Method: Composition-based stats.
Identities = 32/205 (16%), Positives = 72/205 (35%), Gaps = 14/205 (7%)
Query 670 TPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIG 729
+ + + + G+ D+ + + K+P ++ E SSG
Sbjct 818 VEEKVSTRASASSPTGGHVADIYLANLNKLRKRP------EATSIRRTIRPVEEGSSGAA 871
Query 730 GSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDS 789
G SS + D ++ ++ +V S HS + +V QV + + + S
Sbjct 872 GGLKTSSMPAGGLAKDSSDKRPVSAHSVLNSITRHSSLKTKVEGPQVRKSTPTGRSKSFS 931
Query 790 EERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVNEEDFVRLK 849
RP D +++ V+ + + + + ++ ER V + L+
Sbjct 932 NHRPLDPEVIAQVEHSSQDI--------EATMNTALSELRELERQSNVKHAPDVVLDTLE 983
Query 850 QQISDHISQSCGSGQMKMFQEVSAA 874
Q S S+ ++ +E ++
Sbjct 984 QLKSGGTSEPSSPLHSRLLREAESS 1008
>sp|Q8BGT8|PHIPL_MOUSE Phytanoyl-CoA hydroxylase-interacting protein-like
OS=Mus musculus OX=10090 GN=Phyhipl PE=1 SV=1
Length=375
Score = 38.3 bits (87), Expect = 0.29, Method: Composition-based stats.
Identities = 26/110 (24%), Positives = 41/110 (37%), Gaps = 13/110 (12%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS-- 282
PHN+ + N K++W S I Y I K+ ++ +D +
Sbjct 52 PHNIKINNI--TCDSFKISWDMDSKSKDRITHYFIDLNKKENKNSNKFKHKDVPTKLVAK 109
Query 283 ----SFTVQD---LKPFTEYVFRIR--CMKEDGKGYWSDWSEEASGITYE 323
TV+ L P TEY ++ + DG S+WSE T +
Sbjct 110 AVPLPMTVRGHWFLSPRTEYTVAVQTASKQVDGDYVVSEWSEIIEFCTAD 159
>sp|Q6AYN4|PHIPL_RAT Phytanoyl-CoA hydroxylase-interacting protein-like
OS=Rattus norvegicus OX=10116 GN=Phyhipl PE=1 SV=2
Length=375
Score = 38.3 bits (87), Expect = 0.29, Method: Composition-based stats.
Identities = 26/110 (24%), Positives = 41/110 (37%), Gaps = 13/110 (12%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS-- 282
PHN+ + N K++W S I Y I K+ ++ +D +
Sbjct 52 PHNIKINNI--TCDSFKISWDMDSKSKDRITHYFIDLNKKENKNSNKFKHKDVPTKLVAK 109
Query 283 ----SFTVQD---LKPFTEYVFRIR--CMKEDGKGYWSDWSEEASGITYE 323
TV+ L P TEY ++ + DG S+WSE T +
Sbjct 110 AVPLPMTVRGHWFLSPRTEYTVAVQTASKQVDGDYVVSEWSEIIEFCTAD 159
>sp|Q8IU57|INLR1_HUMAN Interferon lambda receptor 1 OS=Homo sapiens
OX=9606 GN=IFNLR1 PE=1 SV=1
Length=520
Score = 38.3 bits (87), Expect = 0.32, Method: Composition-based stats.
Identities = 32/203 (16%), Positives = 66/203 (33%), Gaps = 22/203 (11%)
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQED---GTVH 478
P ++ ++ +++ W + + + + V +P W++ + GT
Sbjct 22 PRLAPPQNVTLLSQNFSVYLTWLPGLGNPQD--VTYFVAYQSSPTRRRWREVEECAGTKE 79
Query 479 RTYLRGNLAESKCYLI---TVTPV--YADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKN 533
L + Y V V + P YL + P+ V T+
Sbjct 80 LLCSMMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLTQTEEIL 139
Query 534 EAVLEWDQLPVDVQNGFIRNYTI-FYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRM 592
A + P Y + F++ GN+T V ++ L +
Sbjct 140 SANATYQLPPCMPP--LDLKYEVAFWKEGAGNKTLFPVTPHGQPVQIT-LQPAASEHHCL 196
Query 593 AAYTDEGGKDGPEFTFTTPKFAQ 615
+A T +TF+ PK+++
Sbjct 197 SART--------IYTFSVPKYSK 211
>sp|P78612|PALF_EMENI pH-response regulator protein palF/RIM8
OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46
/ NRRL 194 / M139) OX=227321 GN=palF PE=2 SV=1
Length=775
Score = 38.3 bits (87), Expect = 0.41, Method: Composition-based stats.
Identities = 40/196 (20%), Positives = 58/196 (30%), Gaps = 46/196 (23%)
Query 652 WPNVPDPSKSHIAQWSPHTPPR----------------HNFNSKDQMYSDGNFTDVSVVE 695
WP+ P+ S+ + P T P Q D S VE
Sbjct 591 WPDYPEQSEHEHYPFQPGTLPSPQPDEPMDEKARLRRAEQTLLPSQPPCDPEAGPSSAVE 650
Query 696 IEANDKKPFPEDLKSLDLFKKEKINTEGHS-------------SGIGGS---SCMSSSRP 739
PED D G + + I GS S SRP
Sbjct 651 AAMPTAPVLPEDDHLNDYHHLPSTTVNGMTGMAPALMSAESVQTVIAGSSSAPLTSPSRP 710
Query 740 SISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSES--TQPLLDSEERPEDLQ 797
S E E + ++ P + R++ + P+ ++ +D Q
Sbjct 711 SEEDKQELERQR----------LMMEASAPGDPDARHNDRADDGPSAPIFHDDD--DDQQ 758
Query 798 LVDHVDGGDGILPRQQ 813
LV GD +LPR Q
Sbjct 759 LVGGAANGDELLPRYQ 774
>sp|Q51845|HAGA2_PORGN Hemagglutinin A OS=Porphyromonas gingivalis
OX=837 GN=hagA PE=3 SV=1
Length=2628
Score = 38.3 bits (87), Expect = 0.42, Method: Composition-based stats.
Identities = 29/189 (15%), Positives = 50/189 (26%), Gaps = 18/189 (10%)
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
Y T+ G DAA + + PV +L+ + + W P +
Sbjct 174 GKTYHFTVQ---RQGPGDAASVVVTGEGGNEFAPVQNLQWSVSGQTVTLTWQAPASDKRT 230
Query 453 YILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT----PVYADGPGSPE 508
Y+L + P W D L+ Y +++ +
Sbjct 231 YVLNESFDTQTLPN--GWTMIDADGDG---HNWLSTINVYNTATHTGDGAMFSKSWTASG 285
Query 509 SIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAV 568
K L P V + GK + Q+P +Y +F T
Sbjct 286 GAKIDLSPDNYLVTPKVTVPENGKLSYWVS-SQVPWTN-----EHYGVFLSTTGNEAANF 339
Query 569 NVDSSHTEY 577
+
Sbjct 340 TIKLLEETL 348
>sp|Q8C8T7|ELFN1_MOUSE Protein ELFN1 OS=Mus musculus OX=10090
GN=Elfn1 PE=2 SV=1
Length=828
Score = 38.3 bits (87), Expect = 0.45, Method: Composition-based stats.
Identities = 35/272 (13%), Positives = 74/272 (27%), Gaps = 34/272 (13%)
Query 503 GPGSPESIKAYLKQAPPS--KGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRT 560
G G+ + P P+++ K++ +N A + + + Y
Sbjct 297 GDGTTPLVILTT--LVPQTEARPSMKVKQLTQNSATIMVQLPSPFNRMYTLEQYN----- 349
Query 561 IIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIE- 619
+ T + E L++L + T Y + + + + T PK
Sbjct 350 NSKSFTVSKLTQPQEEIRLTNLYTLTNYTYCVVSTSSGTHHNHTCLTICLPKPPSPPGPV 409
Query 620 ---------AIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHT 670
+ + CL ++ L V +C KR ++ +
Sbjct 410 PSPSTATHYIMTILGCLFGMVLVLGAVYYCLRKRRRQEEKHKKA----VAAAAGSLKKTI 465
Query 671 PPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFP-------EDLKSLDLFKKEKINTEG 723
+ T ++ EA + P+ E K ++ + K
Sbjct 466 IELKYGPEIE-APGLAPLTQGPLLGPEAVTRIPYLPAATSDVEQYKLVESSETPKATKGN 524
Query 724 HSSGIGGSSCMSSSRPSISSSDENESSQNTSS 755
+ G R S E + +
Sbjct 525 YIEVRTGEP---QERRGCELSRPGEPQSSVAE 553
>sp|P16573|CEAM1_RAT Carcinoembryonic antigen-related cell adhesion
molecule 1 OS=Rattus norvegicus OX=10116 GN=Ceacam1 PE=1
SV=4
Length=519
Score = 37.9 bits (86), Expect = 0.46, Method: Composition-based stats.
Identities = 36/210 (17%), Positives = 55/210 (26%), Gaps = 51/210 (24%)
Query 30 YISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSV 89
ISP + SN C W N Q I+ ++
Sbjct 241 VISPPDIYLHQGSNLNLSC-------HADSNPPAQYFWLINEKLQTSSQELFISNITTNN 293
Query 90 TFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKN--------------LSCI 135
+ T +N +T G V IT+ P +P L+C
Sbjct 294 SGTYACFVNNTVT------GLSRTTVKNITVFE--PVTQPSIQITNTTVKELGSVTLTCF 345
Query 136 VNEGKKMRCEWD-GGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNI 194
+ + W + L TL + +T + K + C
Sbjct 346 SKDTG-VSVRWLFNSQSLQLTDRMTLSQDNSTLRIDPIKREDAGDYQC------------ 392
Query 195 EVWVEAENALGKVTSDHINFDPVYKVKPNP 224
E N + S I D V P+P
Sbjct 393 ----EISNPVSFRISHPIKLD----VIPDP 414
>sp|Q9FL63|Y5410_ARATH Inactive leucine-rich repeat receptor-like
serine/threonine-protein kinase At5g24100 OS=Arabidopsis
thaliana OX=3702 GN=At5g24100 PE=1 SV=1
Length=614
Score = 37.9 bits (86), Expect = 0.48, Method: Composition-based stats.
Identities = 13/82 (16%), Positives = 30/82 (37%), Gaps = 4/82 (5%)
Query 613 FAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPP 672
++ I I + VC + ++ C+ KR + P P K +A+ P
Sbjct 247 ISEPAILGIAISVCFVIFFVIAVVIIVCYVKRQRKSETE----PKPDKLKLAKKMPSEKE 302
Query 673 RHNFNSKDQMYSDGNFTDVSVV 694
+ + + ++++ V
Sbjct 303 VSKLGKEKNIEDMEDKSEINKV 324
>sp|P23471|PTPRZ_HUMAN Receptor-type tyrosine-protein phosphatase
zeta OS=Homo sapiens OX=9606 GN=PTPRZ1 PE=1 SV=4
Length=2315
Score = 38.3 bits (87), Expect = 0.48, Method: Composition-based stats.
Identities = 21/90 (23%), Positives = 36/90 (40%), Gaps = 4/90 (4%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P N V E + L +TW P + +I K+ + Y+ D ++
Sbjct 315 PEN--VQADPENYTSLLVTWERPRVVYDTMIEKFAVLYQQLDGEDQTKHEFLTDGYQDLG 372
Query 284 FTVQDLKPFTEYVFRIRCMKEDG-KGYWSD 312
+ +L P YV +I + +G G +SD
Sbjct 373 AILNNLLPNMSYVLQIVAICTNGLYGKYSD 402
>sp|Q62656|PTPRZ_RAT Receptor-type tyrosine-protein phosphatase
zeta OS=Rattus norvegicus OX=10116 GN=Ptprz1 PE=1 SV=1
Length=2316
Score = 38.3 bits (87), Expect = 0.48, Method: Composition-based stats.
Identities = 20/90 (22%), Positives = 37/90 (41%), Gaps = 4/90 (4%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P N V E + L +TW P + +I K+ + Y+ + + ++
Sbjct 315 PEN--VQADPENYTSLLITWERPRVVYDTMIEKFAVLYQPLEGNDQTKHEFLTDGYQDLG 372
Query 284 FTVQDLKPFTEYVFRIRCMKEDG-KGYWSD 312
+ +L P YV +I + +G G +SD
Sbjct 373 AILNNLIPNMSYVLQIVAICSNGLYGKYSD 402
>sp|P21949|MBHL_AZOVI Uptake hydrogenase large subunit OS=Azotobacter
vinelandii OX=354 GN=hoxG PE=3 SV=1
Length=602
Score = 37.9 bits (86), Expect = 0.50, Method: Composition-based stats.
Identities = 20/85 (24%), Positives = 30/85 (35%), Gaps = 2/85 (2%)
Query 300 RCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ-LVWKTLPPFE 358
R K S W +EA G+ + P A W +I + Y+ + W P +
Sbjct 487 RATANVEKWDPSTWPKEAKGVGINEAPRGALGHWIRIKDGKIENYQAIVPTTWNGTPR-D 545
Query 359 ANGKILDYEVTLTRWKSHLQNYTVN 383
G I YE L + + V
Sbjct 546 HLGNIGAYEAALLNTRMERPDEPVE 570
>sp|P59915|HAGA1_PORGI Hemagglutinin A OS=Porphyromonas gingivalis
(strain ATCC BAA-308 / W83) OX=242619 GN=hagA PE=1 SV=1
Length=2164
Score = 37.9 bits (86), Expect = 0.52, Method: Composition-based stats.
Identities = 16/82 (20%), Positives = 26/82 (32%), Gaps = 5/82 (6%)
Query 393 NDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKK 452
Y T+ G DAA + + PV +L+ + + W P +
Sbjct 174 GKTYHFTVQ---RQGPGDAASVVVTGEGGNEFAPVQNLQWSVSGQTVTLTWQAPASDKRT 230
Query 453 YILEWCVLSDKAPCITDWQQED 474
Y+L + P W D
Sbjct 231 YVLNESFDTQTLPN--GWTMID 250
>sp|Q80XZ4|I22R1_MOUSE Interleukin-22 receptor subunit alpha-1
OS=Mus musculus OX=10090 GN=Il22ra1 PE=1 SV=1
Length=581
Score = 37.9 bits (86), Expect = 0.54, Method: Composition-based stats.
Identities = 27/174 (16%), Positives = 60/174 (34%), Gaps = 12/174 (7%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA--KRDTPTSCTVDYS 187
+++ + + + WDGG + +T ++++ + + KA +R T C +
Sbjct 26 QHVKFQSSNFENI-LTWDGGPASTSDTVYSVEYKKYGERKWLAKAGCQRITQKFCNLTME 84
Query 188 TVYFVN-IEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL---KLT 243
T V A +A G + + + P +++ I +L LT
Sbjct 85 TRNHTEFYYAKVTAVSAGGPPVTKMTDRFSSLQHTTIKPPDVTCIPKVRSIQMLVHPTLT 144
Query 244 WTNPSIKSVIILK---YNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
+ L+ +++ YR + + + + L P TE
Sbjct 145 PVLSEDGHQLTLEEIFHDLFYRLELHV--NHTYQMHLEGKQREYEFLGLTPDTE 196
>sp|Q0V9U8|PHIPL_XENTR Phytanoyl-CoA hydroxylase-interacting protein-like
OS=Xenopus tropicalis OX=8364 GN=phyhipl PE=2 SV=1
Length=376
Score = 37.5 bits (85), Expect = 0.56, Method: Composition-based stats.
Identities = 25/110 (23%), Positives = 40/110 (36%), Gaps = 13/110 (12%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS-- 282
PHN+ + N K++W I Y I K+ ++ +D +
Sbjct 53 PHNIKISNI--TCDSFKISWDMDPKSKDRITHYFIDLNKKENKNSNKFKHKDVPTKLVAK 110
Query 283 ----SFTVQD---LKPFTEYVFRIR--CMKEDGKGYWSDWSEEASGITYE 323
TV+ L P TEY ++ + DG S+WSE T +
Sbjct 111 AVPLPMTVRGHWFLSPRTEYTVAVQTASKQVDGDYVVSEWSEIIEFCTAD 160
>sp|C0SVG5|RVE5_ARATH Protein REVEILLE 5 OS=Arabidopsis thaliana
OX=3702 GN=RVE5 PE=2 SV=1
Length=303
Score = 37.1 bits (84), Expect = 0.57, Method: Composition-based stats.
Identities = 33/194 (17%), Positives = 68/194 (35%), Gaps = 31/194 (16%)
Query 697 EANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSST 756
K P +K+ + + + SS S+ + +S ++S
Sbjct 120 RPKRKASHPYPIKAPKNVAYTSLPSSSTLPLLEPGYLYSSDSKSLMGNQAVCASTSSSWN 179
Query 757 VQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFK 816
+ + + + P V +T PL ++ R ED + V V + +
Sbjct 180 HESTNLPKPVIEVEEPGV------SATAPLPNNRCRQEDTERVRAVT--------KPNNE 225
Query 817 QNCSQHES----------------SPDIS-HFERSKQVSSVNEEDFVRLKQQISDHISQS 859
++C + P+ S H +R KQ+ +N E + L Q +S +++
Sbjct 226 ESCEKPHRVMPNFAEVYSFIGSVFDPNTSGHLQRLKQMDPINMETVLLLMQNLSVNLTSP 285
Query 860 CGSGQMKMFQEVSA 873
+ Q ++ SA
Sbjct 286 EFAEQRRLISSYSA 299
>sp|Q82855|REV_JEMBR Protein Rev OS=Jembrana disease virus OX=36370
GN=rev PE=3 SV=1
Length=213
Score = 36.8 bits (83), Expect = 0.58, Method: Composition-based stats.
Identities = 23/66 (35%), Positives = 32/66 (48%), Gaps = 9/66 (14%)
Query 780 SESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSP---DISHFERSKQ 836
S+ + + EER EDL LVD GG P Q+ S S+P +SHF +SK+
Sbjct 110 SDLENRMAELEERFEDLALVDS--GGKN--PAAP--AQSVSPPSSNPFAYSLSHFSKSKR 163
Query 837 VSSVNE 842
V +
Sbjct 164 VDCGEK 169
>sp|P38853|KEL1_YEAST Kelch repeat-containing protein 1 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=KEL1 PE=1 SV=1
Length=1164
Score = 37.5 bits (85), Expect = 0.64, Method: Composition-based stats.
Identities = 40/231 (17%), Positives = 83/231 (36%), Gaps = 27/231 (12%)
Query 654 NVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDL 713
+ P P ++ +P TP H + + S A+ P P+D D
Sbjct 464 DTPTPRNGNLDLATPVTPTSHQTKNMNVPISAAPL---------ASAPSPAPKDFSDADR 514
Query 714 FKKEK----INTE--GHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGY 767
+E ++TE S + S + + ++ +ESSQ + + +
Sbjct 515 LNREVHNRNVSTEHQNQSHPVNSESHLIAEPNILTPYVPSESSQTPVMKITSNKPFDTPT 574
Query 768 RHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPD 827
+ P + SE+ P + ++ P + D++ + I + S +P
Sbjct 575 IQKEPDL-----SETMDPTVGNQRIPSSI-YGDNLTPANQIKNNSPILETLPSNEIKTPQ 628
Query 828 ISHFERSKQVSSVNE--EDFVRLKQQIS-DHISQSCGSGQMKMFQEVSAAD 875
+ E K + +E + Q+I+ D + S K+ ++ + AD
Sbjct 629 NGNIEEIKHLPDADEKIDSTTTFDQEINGDKLGT---SSMSKVEEDGNVAD 676
>sp|B9EKR1|PTPRZ_MOUSE Receptor-type tyrosine-protein phosphatase
zeta OS=Mus musculus OX=10090 GN=Ptprz1 PE=1 SV=1
Length=2312
Score = 37.5 bits (85), Expect = 0.73, Method: Composition-based stats.
Identities = 20/90 (22%), Positives = 36/90 (40%), Gaps = 4/90 (4%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIK-SVIILKYNIQYRTKDASTWSQIPPEDTASTRSS 283
P N V E + L +TW P + +I K+ + Y+ + ++
Sbjct 315 PEN--VQADPENYTSLLVTWERPRVVYDAMIEKFAVLYQPLAGNDQAKHEFLTDGYQDLG 372
Query 284 FTVQDLKPFTEYVFRIRCMKEDG-KGYWSD 312
+ +L P YV +I + +G G +SD
Sbjct 373 AILNNLLPNMSYVLQIVAVCSNGLYGKYSD 402
>sp|Q3SYS8|I22R1_BOVIN Interleukin-22 receptor subunit alpha-1
OS=Bos taurus OX=9913 GN=IL22RA1 PE=2 SV=1
Length=581
Score = 37.1 bits (84), Expect = 0.84, Method: Composition-based stats.
Identities = 28/178 (16%), Positives = 59/178 (33%), Gaps = 20/178 (11%)
Query 130 KNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHK--FADCKAKRDTPTSCTVDYS 187
+++ + + + WDG E+ +T ++++ + + +R T SC +
Sbjct 26 QHVKFQSSNFENI-LTWDGRPESPPDTVYSVQYKTYGEEEWLEKEGCQRITQKSCNLTME 84
Query 188 TVYFVN-IEVWVEAENALGKVTSDHIN-FDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
T V A + G+ + N F + PP + + I+ T+T
Sbjct 85 TSNLTELYYARVTATDGAGRSATKMTNRFSSLQHTSIKPPDVTCIPKVRSIQMIVHPTYT 144
Query 246 NPSIKSV---------IILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTE 294
++ L Y+++ R + + F L P TE
Sbjct 145 PIRAQNGHQLTLENIFQDLLYHLKLRI------NHTYQMHLEGKQREFEFVGLTPDTE 196
>sp|Q9NZU1|FLRT1_HUMAN Leucine-rich repeat transmembrane protein
FLRT1 OS=Homo sapiens OX=9606 GN=FLRT1 PE=1 SV=4
Length=674
Score = 37.1 bits (84), Expect = 0.89, Method: Composition-based stats.
Identities = 22/153 (14%), Positives = 45/153 (29%), Gaps = 33/153 (22%)
Query 524 TVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFY-----RTIIGNETAVNVDSSHTEYT 578
+ K + + + W ++ + + +G+ T V TEY
Sbjct 440 AIHVKALTADSIRITWKATLPAS------SFRLSWLRLGHSPAVGSITETLVQGDKTEYL 493
Query 579 LSSLTSDTLYMVRM------------------AAYTDEGGKDGP---EFTFTTPKFAQGE 617
L++L + Y++ M A T + + P +
Sbjct 494 LTALEPKSTYIICMVTMETSNAYVADETPVCAKAETADSYGPTTTLNQEQNAGPMASLPL 553
Query 618 IEAIVVPVCLAFLLTTLLGV-LFCFNKRDLIKK 649
I V L FL L + + +L+ +
Sbjct 554 AGIIGGAVALVFLFLVLGAICWYVHQAGELLTR 586
>sp|Q5JRC9|FA47A_HUMAN Protein FAM47A OS=Homo sapiens OX=9606
GN=FAM47A PE=1 SV=3
Length=791
Score = 37.1 bits (84), Expect = 0.92, Method: Composition-based stats.
Identities = 42/225 (19%), Positives = 81/225 (36%), Gaps = 14/225 (6%)
Query 656 PDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDL--KSLDL 713
P+P K+ ++ P P + + + +++ + ++ D +D+ +
Sbjct 389 PEPPKTEVSHLHPVPPKTGVCHLRLEPPDTSQVSNLLLYILKVLDSGRTLKDVWDRCEAR 448
Query 714 FKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQY---STVVHSGYRHQ 770
KK K TE H S G C+ +S S++ T S R +
Sbjct 449 VKKTKEPTEPHKSPC-GEPCLQPPETQVSHPHPEHPKTRRRSSLHSQPPKTRRTSSLRSE 507
Query 771 VPSVQVFS--RSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDI 828
P + S RSE + S PE + V LP+ + + +P+
Sbjct 508 PPKTRRTSSLRSEPPKTRRTSSLGPEPPK-TRRVSSLRPELPKSRRVSSLHPEPPKAPES 566
Query 829 SHFE-----RSKQVSSVNEEDFVRLKQQISDHISQSCGSGQMKMF 868
F R+ + + +ED K+ +SD + S +++ F
Sbjct 567 HQFSEPPKIRASYIKELLQEDTPSTKECVSDSLQYRYTSEKLREF 611
>sp|F1P4W9|CFA65_CHICK Cilia- and flagella-associated protein
65 OS=Gallus gallus OX=9031 GN=CFAP65 PE=2 SV=2
Length=1775
Score = 37.1 bits (84), Expect = 0.93, Method: Composition-based stats.
Identities = 19/87 (22%), Positives = 33/87 (38%), Gaps = 0/87 (0%)
Query 362 KILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDF 421
++ YE L W+ + V T +L +L + K+ V PA +
Sbjct 1431 SLVQYERDLQEWEREKERQAVEFTITEQDLRETAHLCEPSAVVRKYKTLPPVKNHPAANQ 1490
Query 422 QATHPVMDLKAFPKDNMLWVEWTTPRE 448
A H L + + + +WV+ PR
Sbjct 1491 PAGHLQRRLLSSKEASHVWVKPEPPRP 1517
>sp|Q95141|INAR2_BOVIN Interferon alpha/beta receptor 2 OS=Bos
taurus OX=9913 GN=IFNAR2 PE=2 SV=1
Length=530
Score = 36.8 bits (83), Expect = 1.0, Method: Composition-based stats.
Identities = 27/167 (16%), Positives = 56/167 (34%), Gaps = 14/167 (8%)
Query 143 RCEWDGGRETHLETNFTLKSEWATHK-----FADCKAKRDTPTSCTVDYSTVYFVNIEVW 197
W+ + + T++TL + + DC T D + V+ +++
Sbjct 51 VLSWELKNHSIVPTHYTLWYTIMSKREDMKVVKDCINV----TRSFCDLTDVWVNTTDMY 106
Query 198 VEAENALGKVTSDHIN---FDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVII 254
+ + I F V +PP V + +S +K + +P I S +
Sbjct 107 IPQVVGFRENAKLVICMGSFFLVPDKPLDPPEFEIVGFTNHISVNVKFQFDSPGILSEEL 166
Query 255 LKY--NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
Y I+ ++ Q + ++ + L P T Y +
Sbjct 167 QFYLAFIEEHAGNSVKRHQPQITGNITKNFNYVIDKLIPNTNYCISV 213
>sp|Q8ND94|LRN4L_HUMAN LRRN4 C-terminal-like protein OS=Homo sapiens
OX=9606 GN=LRRN4CL PE=2 SV=1
Length=238
Score = 36.0 bits (81), Expect = 1.1, Method: Composition-based stats.
Identities = 20/112 (18%), Positives = 37/112 (33%), Gaps = 11/112 (10%)
Query 495 TVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNY 554
V P PG + PP G VR + AV+ W + +Y
Sbjct 65 RVGPAACLCPGLSSPAQ---PPDPPRMG-EVRI-AAEEGRAVVHW-----CAPFSPVLHY 114
Query 555 -TIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPE 605
+ + + ++++ L L +Y+V + A + G P+
Sbjct 115 WLLLWDGSEAAQKGPPLNATVRRAELKGLKPGGIYVVCVVAANEAGASRVPQ 166
>sp|B1H134|FLRT3_XENTR Leucine-rich repeat transmembrane protein
FLRT3 OS=Xenopus tropicalis OX=8364 GN=flrt3 PE=2 SV=1
Length=648
Score = 36.4 bits (82), Expect = 1.4, Method: Composition-based stats.
Identities = 19/104 (18%), Positives = 33/104 (32%), Gaps = 12/104 (12%)
Query 498 PVYADGPGSPESIK--AYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYT 555
PV P I P K T++ K + + W
Sbjct 384 PVTKQPEIRPPDINKIFRTTPIPVKKIITIQVKSITTETIYISWKVALPM------TALR 437
Query 556 IFYR----TIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAY 595
+ ++ + G+ T V TEY L++L ++ Y + M
Sbjct 438 LSWQLGHSPVFGSITETIVTGDRTEYLLTALEPESPYRICMVPM 481
>sp|O31455|YBFO_BACSU Putative hydrolase YbfO OS=Bacillus subtilis
(strain 168) OX=224308 GN=ybfO PE=3 SV=1
Length=446
Score = 36.4 bits (82), Expect = 1.5, Method: Composition-based stats.
Identities = 18/104 (17%), Positives = 35/104 (34%), Gaps = 2/104 (2%)
Query 446 PRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPG 505
P++ + + + + I DW Q +G YL L + Y I +
Sbjct 303 PKKKIIVWGHNYHLRKQNTKMIKDWVQLNGPNMGDYLPERLKKQT-YTIGIYAYSGASLD 361
Query 506 SPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNG 549
S ++ +PP G ++ + + D L + G
Sbjct 362 SSDNKTVKPVTSPPPSG-SLEALLKAADRPAVFVDFLHTKNKKG 404
>sp|Q12114|CHS5_YEAST Chitin biosynthesis protein CHS5 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=CHS5 PE=1 SV=1
Length=671
Score = 36.4 bits (82), Expect = 1.5, Method: Composition-based stats.
Identities = 21/97 (22%), Positives = 32/97 (33%), Gaps = 10/97 (10%)
Query 225 PHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSF 284
P + + + L W P LK I YR S + P T +
Sbjct 79 PESPVLKIVNVTQTSCVLAWD-PLKLGSAKLKSLILYR---KGIRSMVIPNPFKVTTT-- 132
Query 285 TVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGIT 321
+ L T Y F+++ + G WSE+ T
Sbjct 133 KISGLSVDTPYEFQLKLITTSGT----LWSEKVILRT 165
>sp|Q95207|INAR2_SHEEP Interferon alpha/beta receptor 2 OS=Ovis
aries OX=9940 GN=IFNAR2 PE=2 SV=2
Length=536
Score = 36.4 bits (82), Expect = 1.6, Method: Composition-based stats.
Identities = 31/166 (19%), Positives = 59/166 (36%), Gaps = 12/166 (7%)
Query 143 RCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT--SCTVDYSTVYFVNIEVWVEA 200
W+ + + T++TL K D K +D D + V+ ++++
Sbjct 51 ILSWELKNRSIVPTHYTLWY-TIMSKPEDMKVVKDCINITRSFCDLTDVWVNRTDMYISQ 109
Query 201 -----ENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIIL 255
ENA+ V S +F +PP V + +S +K +P I S +
Sbjct 110 VVGYRENAV--VVSCMGSFFLASDKPLDPPKFEIVDFTNNISVNVKFRLDSPRIPSEELQ 167
Query 256 KY--NIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRI 299
Y I+ ++ Q + ++ + L P T Y +
Sbjct 168 FYLAFIEEHAGNSVKRHQPQITGNITENFNYVIDKLIPNTNYCISV 213
>sp|Q9P2V4|LRIT1_HUMAN Leucine-rich repeat, immunoglobulin-like
domain and transmembrane domain-containing protein 1 OS=Homo
sapiens OX=9606 GN=LRIT1 PE=2 SV=1
Length=623
Score = 36.0 bits (81), Expect = 1.7, Method: Composition-based stats.
Identities = 13/71 (18%), Positives = 28/71 (39%), Gaps = 5/71 (7%)
Query 229 SVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQD 288
SV + + L W P K+ +++ Y + ++ + ++ T+
Sbjct 433 SVKVVGDTYHSVSLVWKAPQAKN--TTAFSVLYAVFGQHSMRRVIVQ---PGKTRVTITG 487
Query 289 LKPFTEYVFRI 299
L P T+YV +
Sbjct 488 LLPKTKYVACV 498
>sp|Q5BK54|LAG3_RAT Lymphocyte activation gene 3 protein OS=Rattus
norvegicus OX=10116 GN=Lag3 PE=2 SV=1
Length=525
Score = 35.6 bits (80), Expect = 2.6, Method: Composition-based stats.
Identities = 42/225 (19%), Positives = 71/225 (32%), Gaps = 35/225 (16%)
Query 247 PSIKSVIILKYNI------QYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFT-----EY 295
PS + +Y + R+ S + E R F++ L+P T EY
Sbjct 85 PSTRRHPPHRYTVLSVAPGGLRSGRQPLLSHVQLEKRGPQRGDFSLW-LRPATRKDAGEY 143
Query 296 VFRIR-------CMKEDGKGYWSD-WSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTV 347
+R C G S S + PS W ++ S ++ R V
Sbjct 144 HAFVRLPDRDFSCSLRLRVGQASMIASPPGTLK---------PSDWVILNCSFSRPDRPV 194
Query 348 QLVW-KTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLV 406
+ W + + Y + + + + T V D + ++T NL
Sbjct 195 SVHWFQGQSRVPVHNSPRHY-LAESFLLLPQVSPLDSGTWGCVLTYRDGFNVSIT-YNLK 252
Query 407 --GKSDAAVLTIPACDFQATHPVMDL-KAFPKDNMLWVEWTTPRE 448
G A LT+ A + L ++L +WT P
Sbjct 253 VQGLEPVAPLTVYAAEGSRVELPCHLPPVVGTPSLLIAKWTPPGG 297
>sp|P70399|TP53B_MOUSE TP53-binding protein 1 OS=Mus musculus
OX=10090 GN=Tp53bp1 PE=1 SV=3
Length=1969
Score = 35.6 bits (80), Expect = 3.0, Method: Composition-based stats.
Identities = 33/177 (19%), Positives = 66/177 (37%), Gaps = 30/177 (17%)
Query 688 FTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGI----GGSSCMSSSRPSISS 743
F + + + + ++ P D ++ + + T SS + ++ +P+
Sbjct 173 FGVLELSQSQDVEEHTVPYD---VNQEHLQLVTTNSGSSPLSDVDASTAIKCEEQPTEDI 229
Query 744 SDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQL-VDHV 802
+ + S++ TVQ P + E PL+ SE+RP Q+ V V
Sbjct 230 AMIEQPSKDIPVTVQ-------------PGKGIHVVEEQNLPLVRSEDRPSSPQVSVAAV 276
Query 803 DGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQS 859
+ + + R+ + Q S P++S S E+ F + + SD S
Sbjct 277 ETKEQVPARELLEEGPQVQPSSEPEVS---------STQEDLFDQSSKTASDGCSTP 324
>sp|P40931|MPL_MPLV Myeloproliferative leukemia protein OS=Myeloproliferative
leukemia virus OX=11973 GN=V-MPL PE=3 SV=1
Length=184
Score = 34.1 bits (76), Expect = 3.6, Method: Composition-based stats.
Identities = 11/36 (31%), Positives = 16/36 (44%), Gaps = 2/36 (6%)
Query 288 DLKPFTEYVFRIRCM--KEDGKGYWSDWSEEASGIT 321
+L+P Y ++R +G WS WS A T
Sbjct 2 ELRPRARYSLQLRARLNGPTYQGPWSAWSPPARVST 37
>sp|Q9VW97|LSDA_DROME Possible lysine-specific histone demethylase
1 OS=Drosophila melanogaster OX=7227 GN=Su(var)3-3 PE=1
SV=1
Length=890
Score = 34.8 bits (78), Expect = 5.1, Method: Composition-based stats.
Identities = 29/161 (18%), Positives = 53/161 (33%), Gaps = 4/161 (2%)
Query 672 PRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGS 731
P+ N N S N E ++ P D + + K++ SG G +
Sbjct 33 PKRNVNHPPSALSAPNPGQKQKHPDEDSNDAPATSDERRTSRRNRPKVDYSNRPSGSGDT 92
Query 732 SCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEE 791
+ S + + ++ + + S + S + PS S++ DS++
Sbjct 93 ASNDKSGSASMGPNNQQAERRSQSQTRKSEANATSSSVSGPSAGNSRPSQNG----DSKD 148
Query 792 RPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFE 832
R V G R + K ++ PDIS
Sbjct 149 RDAGTPTVLSGQEGAVFQSRLPFNKMTPNEEACFPDISRSG 189
>sp|Q5PQK4|UIMC1_RAT BRCA1-A complex subunit RAP80 OS=Rattus norvegicus
OX=10116 GN=Uimc1 PE=1 SV=1
Length=726
Score = 34.4 bits (77), Expect = 5.2, Method: Composition-based stats.
Identities = 27/116 (23%), Positives = 44/116 (38%), Gaps = 9/116 (8%)
Query 797 QLVDHVDGGDGILPRQQYFKQN-CSQHESSPDISHFERSKQVSSVNEED-----FVRLKQ 850
QLV G+ +LPR + QN C Q E + + H S+ V + E+
Sbjct 313 QLVKKRGFGEPVLPRPPFLIQNECGQEEQTSE-KHEGLSEDVRAGAREERQGSGASVWHS 371
Query 851 QISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQV--ERFETVGMEAATDEGMPKS 904
+ D S + ++ E G ++G E E V + D+ +P S
Sbjct 372 ETKDSQKSPITSLKQRLLLEEEPTTGRGQSSQGLFVEETSEEVLKSSEGDDAVPAS 427
>sp|W8DXL4|LRIT3_MOUSE Leucine-rich repeat, immunoglobulin-like
domain and transmembrane domain-containing protein 3 OS=Mus
musculus OX=10090 GN=Lrit3 PE=1 SV=1
Length=681
Score = 34.4 bits (77), Expect = 6.5, Method: Composition-based stats.
Identities = 48/365 (13%), Positives = 96/365 (26%), Gaps = 67/365 (18%)
Query 339 SHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLA 398
+G+ T QL W ++G ++Y V ++ ++ T ++ D
Sbjct 275 CDAKGHPTPQLTW-----TRSDGSTVNYTVIQESPGEGIRWSIISLTSIS---HKDAGDY 326
Query 399 TLTVRNLVGKSDAAVLTI------------PACDFQATHPVMDLK-AFPKDNMLWVEWTT 445
+NL G S+A V + P + W +
Sbjct 327 RCKAKNLAGISEAVVTVTVVGGVTTTLSPDSSERSPGEPPEQHPQPGLGGSTPPSKSWLS 386
Query 446 PRE-SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVT---PVYA 501
P S Y L + + P+
Sbjct 387 PGLTSAPSYPTPSAALYTSTWSPPPSSLPPIFSAASATTSVQTSISGRTARTSHQPPLLH 446
Query 502 DGPGSPESIKAYLKQAPPSKGP---------------------TVRTKKVGKNEAVLEWD 540
G S I+ ++ PP +R + L W+
Sbjct 447 PGGKSNAKIEKNGRKFPPLSASKKEELALLDQAAPMETNVTIKDLRVARETGVSVTLMWN 506
Query 541 QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDS---SHTEYTLSSLTSDTLYMVRMAAYTD 597
++ T+ Y + G + + V++ + T++ L + Y+ +
Sbjct 507 SSSSTQESSV----TVLY-SKYGEKDLLLVNADDYGKNQATINGLEPGSQYVACVCPK-- 559
Query 598 EGGKDGPEF----TFTT--PKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFN--KRDLIKK 649
GP TF+T + + ++V A ++ L + K
Sbjct 560 ---GVGPREDLCITFSTNRVEGRGSQWSLLLVVTSTACVIVVPLICFLLYKVCKLQCTSD 616
Query 650 HIWPN 654
W
Sbjct 617 PFWEE 621
>sp|A0A571BF63|ANKF1_MOUSE Ankyrin-repeat and fibronectin type
III domain-containing 1 OS=Mus musculus OX=10090 GN=Ankfn1
PE=1 SV=1
Length=1286
Score = 34.1 bits (76), Expect = 7.9, Method: Composition-based stats.
Identities = 14/106 (13%), Positives = 31/106 (29%), Gaps = 7/106 (7%)
Query 222 PNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTR 281
P P N ++ S S + S+ + ++ +Y +++ +
Sbjct 409 PEVPANACLMVSSSTSLTVSFQ-EPLSVNAAVVTRYKVEWSMSKDFSPLAGEIIMDNLQT 467
Query 282 SSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPS 327
T+ L +Y ++ G W + PS
Sbjct 468 LRCTITGLTTGQQYFVQVSAYNMKG------WGPAQTTTPVCASPS 507
>sp|Q9M2Q6|SPL15_ARATH Squamosa promoter-binding-like protein
15 OS=Arabidopsis thaliana OX=3702 GN=SPL15 PE=1 SV=1
Length=354
Score = 33.7 bits (75), Expect = 9.0, Method: Composition-based stats.
Identities = 16/102 (16%), Positives = 31/102 (30%), Gaps = 3/102 (3%)
Query 147 DGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGK 206
+ RETH N + + T +SC + + + + ++ +
Sbjct 186 NPVRETHPHMNVLSHGSSSFTTCPEMINNNSTDSSCALSLLSNSYPIHQQQLQTPTNTWR 245
Query 207 VTS---DHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWT 245
+S I+F + PP + L TW
Sbjct 246 PSSGFDSMISFSDKVTMAQPPPISTHQPPISTHQQYLSQTWE 287
Lambda K H a alpha
0.318 0.119 0.320 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0365 0.140 1.90 42.6 43.6
Effective search space used: 106093335362
Database: uniprot_sprot.fasta
Posted date: Apr 3, 2024 12:05 PM
Number of letters in database: 206,678,396
Number of sequences in database: 571,282
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40