PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,282 sequences; 206,678,396 total letters
Results from round 1
Query= sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1 SV=1
Length=7096
Score E
Sequences producing significant alignments: (Bits) Value
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re... 14825 0.0
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res... 12978 0.0
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus... 12924 0.0
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus... 12917 0.0
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus... 12908 0.0
sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute resp... 9137 0.0
sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respi... 7474 0.0
sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus H... 7447 0.0
sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus R... 7445 0.0
sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus 2... 7442 0.0
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus... 6357 0.0
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res... 5991 0.0
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus... 5976 0.0
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus... 5612 0.0
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus... 5604 0.0
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi... 5427 0.0
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi... 5423 0.0
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir... 5406 0.0
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir... 5395 0.0
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir... 5394 0.0
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi... 5381 0.0
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir... 5341 0.0
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir... 5340 0.0
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir... 5337 0.0
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi... 5337 0.0
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir... 5261 0.0
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus... 4347 0.0
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir... 4306 0.0
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi... 4290 0.0
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir... 4258 0.0
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi... 4213 0.0
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir... 4188 0.0
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious... 4156 0.0
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou... 4155 0.0
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious... 4152 0.0
sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus H... 2550 0.0
sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respi... 2192 0.0
sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus H... 2172 0.0
sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronaviru... 1872 0.0
sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronaviru... 1871 0.0
sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus... 1860 0.0
sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus... 1859 0.0
sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus... 1858 0.0
sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus... 1834 0.0
sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronaviru... 1834 0.0
sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus 1... 1831 0.0
sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus H... 1828 0.0
sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronaviru... 1828 0.0
sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus... 1825 0.0
sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus... 1823 0.0
sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus... 1818 0.0
sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus 5... 1228 0.0
sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus... 1189 0.0
sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic ... 1185 0.0
sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus... 1181 0.0
sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmiss... 1127 0.0
sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious ... 1113 0.0
sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious b... 1113 0.0
sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious b... 1108 0.0
sp|P18457|R1AB_CVPFS Replicase polyprotein 1ab (Fragment) OS=Porc... 518 2e-162
sp|Q9WQ77|R1AB_CVRSD Replicase polyprotein 1ab (Fragment) OS=Rat ... 484 4e-154
sp|Q9WQ76|R1AB_CVTMI Replicase polyprotein 1ab (Fragment) OS=Turk... 445 2e-140
sp|P12723|R1AB_IBVK Replicase polyprotein 1ab (Fragment) OS=Avian... 439 4e-135
sp|P36697|R1AB_CVCAI Replicase polyprotein 1ab (Fragment) OS=Cani... 183 3e-51
sp|Q04158|R1AB_CVPR8 Replicase polyprotein 1ab (Fragment) OS=Porc... 127 3e-32
sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11... 137 4e-30
sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream vir... 133 1e-28
sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus 1 OX... 127 4e-27
sp|Q4J9D2|Y1252_SULAC Uncharacterized protein Saci_1252 OS=Sulfol... 73.2 1e-12
sp|Q97UU4|Y2899_SACS2 Uncharacterized protein SSO2899 OS=Saccharo... 72.8 2e-12
sp|Q8ZXT3|Y1111_PYRAE Uncharacterized protein PAE1111 OS=Pyrobacu... 72.8 2e-12
sp|Q9WYX8|Y508_THEMA Uncharacterized protein TM_0508 OS=Thermotog... 76.3 8e-12
sp|Q96XY5|Y2383_SULTO Uncharacterized protein STK_23830 OS=Sulfur... 67.0 2e-10
sp|P0C6F3|R1A_BEV Replicase polyprotein 1a OS=Berne virus OX=1115... 65.5 2e-08
sp|P36327|POLN_EEVV3 Polyprotein P1234 OS=Venezuelan equine encep... 63.2 1e-07
sp|Q8CAS9|PARP9_MOUSE Protein mono-ADP-ribosyltransferase PARP9 O... 62.8 1e-07
sp|P27282|POLN_EEVVT Polyprotein P1234 OS=Venezuelan equine encep... 62.4 2e-07
sp|P36328|POLN_EEVVP Polyprotein P1234 OS=Venezuelan equine encep... 62.4 2e-07
sp|A7MG20|YMDB_CROS8 O-acetyl-ADP-ribose deacetylase OS=Cronobact... 58.2 2e-07
sp|E1SDF1|YMDB1_PANVC O-acetyl-ADP-ribose deacetylase 1 OS=Pantoe... 57.0 5e-07
sp|A8AI35|YMDB_CITK8 O-acetyl-ADP-ribose deacetylase OS=Citrobact... 56.6 8e-07
sp|Q8V294|POLN_EEVVC Polyprotein P1234 OS=Venezuelan equine encep... 59.3 2e-06
sp|B6SFA4|MAA3_ARATH Probable helicase MAGATAMA 3 OS=Arabidopsis ... 58.9 2e-06
sp|C9Y0V8|YMDB_CROTZ O-acetyl-ADP-ribose deacetylase OS=Cronobact... 55.1 2e-06
sp|B5F961|YMDB_SALA4 O-acetyl-ADP-ribose deacetylase OS=Salmonell... 54.3 5e-06
sp|A4W960|YMDB_ENT38 O-acetyl-ADP-ribose deacetylase OS=Enterobac... 53.9 6e-06
sp|P67341|YMDB_SALTY O-acetyl-ADP-ribose deacetylase OS=Salmonell... 53.5 7e-06
sp|P67342|YMDB_SALTI O-acetyl-ADP-ribose deacetylase OS=Salmonell... 53.5 7e-06
sp|P0A8D6|YMDB_ECOLI O-acetyl-ADP-ribose deacetylase OS=Escherich... 53.1 9e-06
sp|P0A8D7|YMDB_ECOL6 O-acetyl-ADP-ribose deacetylase OS=Escherich... 53.1 9e-06
sp|P0A8D8|YMDB_ECO57 O-acetyl-ADP-ribose deacetylase OS=Escherich... 53.1 9e-06
sp|D3RKJ0|YMDB_KLEVT O-acetyl-ADP-ribose deacetylase OS=Klebsiell... 53.1 9e-06
sp|B5XXK9|YMDB_KLEP3 O-acetyl-ADP-ribose deacetylase OS=Klebsiell... 53.1 9e-06
sp|B4T2X8|YMDB_SALNS O-acetyl-ADP-ribose deacetylase OS=Salmonell... 53.1 1e-05
sp|Q9WJC7|POLN_EEVVM Polyprotein P1234 OS=Venezuelan equine encep... 56.6 1e-05
sp|Q460N5|PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14 ... 56.2 1e-05
sp|D5CE05|YMDB_ENTCC O-acetyl-ADP-ribose deacetylase OS=Enterobac... 52.0 3e-05
sp|Q72M93|Y3295_LEPIC Macro domain-containing protein LIC_13295 O... 51.6 3e-05
sp|Q8EYT0|Y4133_LEPIN Macro domain-containing protein LA_4133 OS=... 51.6 3e-05
sp|B5RBF3|YMDB_SALG2 O-acetyl-ADP-ribose deacetylase OS=Salmonell... 51.6 4e-05
sp|B7LT90|YMDB_ESCF3 O-acetyl-ADP-ribose deacetylase OS=Escherich... 51.2 5e-05
sp|Q0T5Z6|YMDB_SHIF8 O-acetyl-ADP-ribose deacetylase OS=Shigella ... 50.8 7e-05
sp|P0C6F4|R1A_BRV1 Replicase polyprotein 1a OS=Breda virus 1 OX=3... 53.5 1e-04
sp|D2TT52|YMDB_CITRI O-acetyl-ADP-ribose deacetylase OS=Citrobact... 50.1 1e-04
sp|Q32E73|YMDB_SHIDS O-acetyl-ADP-ribose deacetylase OS=Shigella ... 49.7 1e-04
sp|Q8RHQ2|Y1951_FUSNN Uncharacterized protein FN1951 OS=Fusobacte... 49.3 2e-04
sp|Q2EMV9|PAR14_MOUSE Protein mono-ADP-ribosyltransferase PARP14 ... 51.6 3e-04
sp|Q8Q0F9|Y177_METMA Macro domain-containing protein MM_0177 OS=M... 48.5 4e-04
sp|Q87JZ5|Y4103_VIBPA Macro domain-containing protein VPA0103 OS=... 47.8 7e-04
sp|Q8IXQ6|PARP9_HUMAN Protein mono-ADP-ribosyltransferase PARP9 O... 50.4 7e-04
sp|Q8RB30|Y995_CALS4 Macro domain-containing protein TTE0995 OS=C... 47.4 8e-04
sp|E1PL40|YMDB2_PANVC O-acetyl-ADP-ribose deacetylase 2 OS=Pantoe... 47.4 0.001
sp|Q8TQD0|Y1614_METAC Macro domain-containing protein MA_1614 OS=... 47.8 0.001
sp|Q92355|SEN1_SCHPO Helicase sen1 OS=Schizosaccharomyces pombe (... 49.7 0.001
sp|P38859|DNA2_YEAST DNA replication ATP-dependent helicase/nucle... 49.3 0.002
sp|Q8Y2K1|Y334_RALN1 Macro domain-containing protein RSc0334 OS=R... 46.2 0.002
sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 OS=Arabidopsis th... 48.5 0.003
sp|Q68772|RPOA_SHFV Replicase polyprotein 1ab OS=Simian hemorrhag... 48.1 0.004
sp|Q9EYI6|Y189_STRNO Macro domain-containing protein in sno 5'reg... 45.4 0.005
sp|Q9WJB2|RPOA_PRRSR Replicase polyprotein 1ab OS=Porcine reprodu... 47.8 0.006
sp|Q8KAE4|Y2219_CHLTE Macro domain-containing protein CT2219 OS=C... 44.7 0.007
sp|Q97AU0|Y719_THEVO Uncharacterized protein TV0719 OS=Thermoplas... 45.1 0.007
sp|Q93SX7|Y189_ACISE Macro domain-containing protein OS=Acinetoba... 44.7 0.008
sp|A6YQT5|RPOA_PRRSV Replicase polyprotein 1ab OS=Porcine reprodu... 47.0 0.009
sp|Q88SK6|Y3408_LACPL Macro domain-containing protein lp_3408 OS=... 44.3 0.010
sp|Q985D2|Y7730_RHILO Macro domain-containing protein mll7730 OS=... 44.3 0.010
sp|Q8B912|RPOA_PRRSB Replicase polyprotein 1ab OS=Porcine reprodu... 47.0 0.011
sp|P30771|RENT1_YEAST ATP-dependent helicase NAM7 OS=Saccharomyce... 46.6 0.011
sp|Q9YN02|RPOA_PRRS1 Replicase polyprotein 1ab OS=Porcine reprodu... 46.6 0.013
sp|O59182|Y1513_PYRHO Uncharacterized protein PH1513 OS=Pyrococcu... 43.5 0.021
sp|Q9V0Y3|Y656_PYRAB Uncharacterized protein PYRAB06560 OS=Pyroco... 43.1 0.026
sp|P19811|RPOA_EAVBU Replicase polyprotein 1ab OS=Equine arteriti... 45.4 0.028
sp|P27283|POLN_SINDO Polyprotein P1234 OS=Sindbis virus subtype O... 45.4 0.031
sp|Q8P5Z8|Y3184_XANCP Macro domain-containing protein XCC3184 OS=... 42.7 0.032
sp|Q8PHB6|Y3343_XANAC Macro domain-containing protein XAC3343 OS=... 42.7 0.035
sp|Q9HJ67|Y1105_THEAC Uncharacterized protein Ta1105 OS=Thermopla... 42.7 0.043
sp|Q8BCR0|POLN_RUBVN Non-structural polyprotein p200 OS=Rubella v... 44.3 0.056
sp|Q6PAV8|MACD2_XENLA ADP-ribose glycohydrolase MACROD2 OS=Xenopu... 43.5 0.069
sp|Q9BQ69|MACD1_HUMAN ADP-ribose glycohydrolase MACROD1 OS=Homo s... 42.7 0.089
sp|Q86924|POLN_AURAV Polyprotein P1234 OS=Aura virus OX=44158 PE=... 43.9 0.089
sp|Q7MTZ7|MACRO_PORGI Macro domain-containing protein PG1779 OS=P... 41.2 0.11
sp|P13889|POLN_RUBVT Non-structural polyprotein p200 OS=Rubella v... 43.5 0.11
sp|Q9ZBG3|Y6450_STRCO Macro domain-containing protein SCO6450 OS=... 41.2 0.12
sp|Q8K4G6|MACD1_RAT ADP-ribose glycohydrolase MACROD1 (Fragment) ... 42.0 0.14
sp|O40955|POLN_RUBVR Non-structural polyprotein p200 OS=Rubella v... 43.1 0.14
sp|P03317|POLN_SINDV Polyprotein P1234 OS=Sindbis virus OX=11034 ... 42.4 0.22
sp|A0A1P8ASY1|JHS1_ARATH DNA replication ATP-dependent helicase/n... 42.4 0.23
sp|O28751|Y1521_ARCFU ADP-ribose glycohydrolase AF_1521 OS=Archae... 40.4 0.24
sp|Q306W6|POLN_EEEV1 Polyprotein P1234 OS=Eastern equine encephal... 42.4 0.26
sp|Q44020|YGB2_CUPNE Macro domain-containing protein in gbd 3'reg... 40.0 0.27
sp|Q9YBE9|Y1648_AERPE Uncharacterized protein APE_1648.1 OS=Aerop... 40.0 0.33
sp|Q2KHU5|MACD1_BOVIN ADP-ribose glycohydrolase MACROD1 OS=Bos ta... 40.8 0.35
sp|Q9BYK8|HELZ2_HUMAN 3'-5' exoribonuclease HELZ2 OS=Homo sapiens... 41.2 0.52
sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens ... 41.2 0.58
sp|P13896|POLN_WEEV Polyprotein P1234 OS=Western equine encephali... 41.2 0.60
sp|P18479|POLG_ZYMVC Genome polyprotein OS=Zucchini yellow mosaic... 41.2 0.61
sp|Q9HEH1|RENT1_NEUCR Regulator of nonsense transcripts 1 homolog... 40.8 0.61
sp|Q9VHM2|VP35L_DROME VPS35 endosomal protein sorting factor-like... 40.8 0.68
sp|Q09449|YQ12_CAEEL Uncharacterized ATP-dependent helicase C05C1... 40.8 0.71
sp|A2AKX3|SETX_MOUSE Probable helicase senataxin OS=Mus musculus ... 40.4 0.90
sp|Q9FJR0|RENT1_ARATH Regulator of nonsense transcripts 1 homolog... 40.4 0.98
sp|Q922B1|MACD1_MOUSE ADP-ribose glycohydrolase MACROD1 OS=Mus mu... 39.7 1.0
sp|P32644|ECM32_YEAST Putative ATP-dependent RNA helicase ECM32 O... 40.0 1.1
sp|Q306W8|POLN_EEEV8 Polyprotein P1234 OS=Eastern equine encephal... 40.0 1.1
sp|Q9HXU7|Y3693_PSEAE Macro domain-containing protein PA3693 OS=P... 38.1 1.3
sp|Q09820|RENT1_SCHPO ATP-dependent helicase upf1 OS=Schizosaccha... 39.7 1.6
sp|Q98TR3|RENT1_TAKRU Putative regulator of nonsense transcripts ... 38.5 3.1
sp|Q9RUV0|PPDE_DEIRA Phosphatase/phosphodiesterase DR_1281 OS=Dei... 37.7 3.1
sp|Q06502|RPOA_LDVC Replicase polyprotein 1ab OS=Lactate dehydrog... 38.5 3.1
sp|P18478|POLG_WMV2U Genome polyprotein (Fragment) OS=Watermelon ... 38.5 3.3
sp|Q54I89|RENT1_DICDI Regulator of nonsense transcripts 1 OS=Dict... 38.5 3.4
sp|Q99IE5|POLN_RUBVV Non-structural polyprotein p200 OS=Rubella v... 38.5 3.4
sp|Q99IE7|POLN_RUBVO Non-structural polyprotein p200 OS=Rubella v... 38.5 3.4
sp|Q4QXJ8|POLN_EEEVF Polyprotein P1234 OS=Eastern equine encephal... 38.5 3.5
sp|Q9KHE2|Y189_STRGR Macro domain-containing protein in non 5'reg... 36.6 3.7
sp|O76512|RENT1_CAEEL Regulator of nonsense transcripts 1 OS=Caen... 38.1 3.7
sp|Q7TZB9|Y1934_MYCBO Uncharacterized protein Mb1934c OS=Mycobact... 37.7 4.0
sp|P9WK29|Y1899_MYCTU Uncharacterized protein Rv1899c OS=Mycobact... 37.7 4.0
sp|P9WK28|Y1899_MYCTO Uncharacterized protein MT1950 OS=Mycobacte... 37.7 4.1
sp|P26627|R1AB_CVMJD Replicase polyprotein 1ab (Fragment) OS=Muri... 37.7 4.2
sp|E9QAM5|HELZ2_MOUSE 3'-5' exoribonuclease HELZ2 OS=Mus musculus... 38.1 4.2
sp|Q6X2U4|POLN_RUBVB Non-structural polyprotein p200 OS=Rubella v... 38.1 4.4
sp|Q8Y3S3|Y2759_LISMO Macro domain-containing protein lmo2759 OS=... 36.6 4.5
sp|Q04561|RPOA_PRRSL Replicase polyprotein 1ab OS=Porcine reprodu... 38.1 4.6
sp|A0A339|NDHK_COFAR NAD(P)H-quinone oxidoreductase subunit K, ch... 37.0 4.8
sp|Q89330|POLG_ZYMVR Genome polyprotein OS=Zucchini yellow mosaic... 38.1 4.9
sp|Q6X2U2|POLN_RUBVC Non-structural polyprotein p200 OS=Rubella v... 38.1 4.9
sp|A0A0D2UG83|H2AY_CAPO3 Histone macroH2A1.1 OS=Capsaspora owczar... 37.4 5.1
sp|Q926Y8|Y2902_LISIN Macro domain-containing protein lin2902 OS=... 36.2 5.4
sp|A0MD28|RPOA_PRRSS Replicase polyprotein 1ab OS=Porcine reprodu... 37.7 5.9
sp|Q3UYG8|MACD2_MOUSE ADP-ribose glycohydrolase MACROD2 OS=Mus mu... 37.4 6.0
sp|B4S3G9|PDXJ_PROA2 Pyridoxine 5'-phosphate synthase OS=Prosthec... 36.6 6.1
sp|Q71W03|Y2748_LISMF Macro domain-containing protein LMOf2365_27... 35.8 6.4
sp|A1Z1Q3|MACD2_HUMAN ADP-ribose glycohydrolase MACROD2 OS=Homo s... 37.0 7.0
sp|Q83017|RPOA_LDVP Replicase polyprotein 1ab OS=Lactate dehydrog... 37.4 7.5
sp|Q9J6K9|POLN_RUBVD Non-structural polyprotein p200 OS=Rubella v... 37.4 8.0
sp|Q86500|POLN_RUBVM Non-structural polyprotein p200 OS=Rubella v... 37.0 9.1
sp|Q3ZX83|TIG_DEHMC Trigger factor OS=Dehalococcoides mccartyi (s... 36.6 9.7
sp|Q5ZKG3|DNA2_CHICK DNA replication ATP-dependent helicase/nucle... 37.0 9.9
sp|B0C385|RPOC2_ACAM1 DNA-directed RNA polymerase subunit beta' O... 37.0 9.9
>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1
SV=1
Length=7096
Score = 14825 bits (38475), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 7096/7096 (100%), Positives = 7096/7096 (100%), Gaps = 0/7096 (0%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV
Sbjct 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK
Sbjct 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW
Sbjct 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI
Sbjct 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL
Sbjct 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC
Sbjct 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF
Sbjct 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA
Sbjct 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY
Sbjct 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV
Sbjct 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC
Sbjct 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG
Sbjct 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN 840
TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN
Sbjct 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN 840
Query 841 ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW 900
ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW
Sbjct 841 ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW 900
Query 901 SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL 960
SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL
Sbjct 901 SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL 960
Query 961 EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV 1020
EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV
Sbjct 961 EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV 1020
Query 1021 QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN
Sbjct 1021 QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
Query 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ 1140
NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ
Sbjct 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ 1140
Query 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE 1200
HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE
Sbjct 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE 1200
Query 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN 1260
QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN
Sbjct 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN 1260
Query 1261 GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV 1320
GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV
Sbjct 1261 GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV 1320
Query 1321 PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA 1380
PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA
Sbjct 1321 PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA 1380
Query 1381 HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND 1440
HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND
Sbjct 1381 HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND 1440
Query 1441 LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH 1500
LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH
Sbjct 1441 LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH 1500
Query 1501 FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL 1560
FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL
Sbjct 1501 FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL 1560
Query 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV
Sbjct 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
Query 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL
Sbjct 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
Query 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN
Sbjct 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
Query 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ
Sbjct 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
Query 1801 ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK 1860
ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK
Sbjct 1801 ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK 1860
Query 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY 1920
GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY
Sbjct 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY 1920
Query 1921 PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK
Sbjct 1921 PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
Query 1981 KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA 2040
KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA
Sbjct 1981 KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA 2040
Query 2041 CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV
Sbjct 2041 CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
Query 2101 DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC 2160
DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC
Sbjct 2101 DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC 2160
Query 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS
Sbjct 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
Query 2221 PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT 2280
PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT
Sbjct 2221 PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT 2280
Query 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV
Sbjct 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
Query 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV
Sbjct 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA
Sbjct 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH
Sbjct 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV
Sbjct 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG
Sbjct 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
Query 2641 FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN 2700
FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN
Sbjct 2641 FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN 2700
Query 2701 AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL 2760
AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL
Sbjct 2701 AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL 2760
Query 2761 KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI 2820
KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI
Sbjct 2761 KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI 2820
Query 2821 ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD 2880
ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD
Sbjct 2821 ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD 2880
Query 2881 FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE 2940
FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE
Sbjct 2881 FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE 2940
Query 2941 GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST 3000
GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST
Sbjct 2941 GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST 3000
Query 3001 SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL
Sbjct 3001 SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
Query 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV
Sbjct 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
Query 3121 SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL 3180
SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL
Sbjct 3121 SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL 3180
Query 3181 CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND 3240
CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND
Sbjct 3181 CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND 3240
Query 3241 FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY 3300
FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY
Sbjct 3241 FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY 3300
Query 3301 CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK 3360
CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK
Sbjct 3301 CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK 3360
Query 3361 TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV 3420
TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV
Sbjct 3361 TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV 3420
Query 3421 SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR 3480
SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR
Sbjct 3421 SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR 3480
Query 3481 WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN
Sbjct 3481 WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
Query 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW
Sbjct 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
Query 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV
Sbjct 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
Query 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK
Sbjct 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
Query 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM
Sbjct 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
Query 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL
Sbjct 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
Query 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL
Sbjct 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
Query 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA
Sbjct 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
Query 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED
Sbjct 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
Query 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY
Sbjct 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
Query 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ 4140
KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ
Sbjct 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ 4140
Query 4141 NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD 4200
NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD
Sbjct 4141 NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD 4200
Query 4201 GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV 4260
GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV
Sbjct 4201 GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV 4260
Query 4261 PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES 4320
PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES
Sbjct 4261 PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES 4320
Query 4321 FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG 4380
FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG
Sbjct 4321 FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG 4380
Query 4381 CSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKF 4440
CSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKF
Sbjct 4381 CSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKF 4440
Query 4441 LKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDG 4500
LKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDG
Sbjct 4441 LKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDG 4500
Query 4501 DMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVEN 4560
DMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVEN
Sbjct 4501 DMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVEN 4560
Query 4561 PDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPG 4620
PDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPG
Sbjct 4561 PDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPG 4620
Query 4621 SGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFK 4680
SGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFK
Sbjct 4621 SGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFK 4680
Query 4681 YWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHF 4740
YWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHF
Sbjct 4681 YWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHF 4740
Query 4741 RELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQ 4800
RELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQ
Sbjct 4741 RELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQ 4800
Query 4801 TVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQ 4860
TVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQ
Sbjct 4801 TVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQ 4860
Query 4861 LLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALF 4920
LLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALF
Sbjct 4861 LLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALF 4920
Query 4921 AYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVV 4980
AYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVV
Sbjct 4921 AYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVV 4980
Query 4981 IGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSL 5040
IGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSL
Sbjct 4981 IGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSL 5040
Query 5041 SHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALL 5100
SHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALL
Sbjct 5041 SHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALL 5100
Query 5101 STDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNS 5160
STDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNS
Sbjct 5101 STDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNS 5160
Query 5161 TYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVY 5220
TYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVY
Sbjct 5161 TYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVY 5220
Query 5221 LPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYI 5280
LPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYI
Sbjct 5221 LPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYI 5280
Query 5281 RKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRC 5340
RKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRC
Sbjct 5281 RKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRC 5340
Query 5341 GACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHK 5400
GACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHK
Sbjct 5341 GACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHK 5400
Query 5401 PPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAE 5460
PPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAE
Sbjct 5401 PPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAE 5460
Query 5461 TLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIG 5520
TLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIG
Sbjct 5461 TLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIG 5520
Query 5521 EYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTL 5580
EYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTL
Sbjct 5521 EYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTL 5580
Query 5581 NISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDA 5640
NISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDA
Sbjct 5581 NISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDA 5640
Query 5641 LCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEI 5700
LCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEI
Sbjct 5641 LCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEI 5700
Query 5701 SMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDM 5760
SMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDM
Sbjct 5701 SMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDM 5760
Query 5761 FLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVV 5820
FLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVV
Sbjct 5761 FLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVV 5820
Query 5821 REFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC 5880
REFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC
Sbjct 5821 REFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC 5880
Query 5881 NVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVI 5940
NVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVI
Sbjct 5881 NVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVI 5940
Query 5941 TGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFIT 6000
TGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFIT
Sbjct 5941 TGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFIT 6000
Query 6001 REEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSR 6060
REEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSR
Sbjct 6001 REEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSR 6060
Query 6061 VSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSM 6120
VSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSM
Sbjct 6061 VSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSM 6120
Query 6121 KYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQS 6180
KYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQS
Sbjct 6121 KYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQS 6180
Query 6181 NHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHM 6240
NHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHM
Sbjct 6181 NHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHM 6240
Query 6241 VVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSD 6300
VVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSD
Sbjct 6241 VVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSD 6300
Query 6301 KFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSA 6360
KFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSA
Sbjct 6301 KFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSA 6360
Query 6361 FVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYL 6420
FVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYL
Sbjct 6361 FVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYL 6420
Query 6421 DAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIIN 6480
DAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIIN
Sbjct 6421 DAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIIN 6480
Query 6481 NTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDY 6540
NTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDY
Sbjct 6481 NTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDY 6540
Query 6541 KRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSV 6600
KRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSV
Sbjct 6541 KRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSV 6600
Query 6601 KGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQ 6660
KGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQ
Sbjct 6601 KGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQ 6660
Query 6661 MEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDF 6720
MEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDF
Sbjct 6661 MEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDF 6720
Query 6721 IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEIS 6780
IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEIS
Sbjct 6721 IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEIS 6780
Query 6781 FMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMM 6840
FMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMM
Sbjct 6781 FMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMM 6840
Query 6841 NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND 6900
NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND
Sbjct 6841 NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND 6900
Query 6901 FVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLA 6960
FVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLA
Sbjct 6901 FVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLA 6960
Query 6961 LGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGY 7020
LGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGY
Sbjct 6961 LGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGY 7020
Query 7021 VMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLII 7080
VMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLII
Sbjct 7021 VMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLII 7080
Query 7081 RENNRVVISSDVLVNN 7096
RENNRVVISSDVLVNN
Sbjct 7081 RENNRVVISSDVLVNN 7096
>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score = 12978 bits (33681), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 6117/7103 (86%), Positives = 6590/7103 (93%), Gaps = 37/7103 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA + HGH +VELVAE++GIQYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGK+ CTLSEQLD+I++KRGVYCCR+HEHEIAW
Sbjct 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVASP ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + E+GPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+Q+S+L+PL F S+A
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIF+RTL+ A +S+ LQ+AA+TILDGIS+ SLRL+DAM++TSDL TN++++MAY
Sbjct 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ TSQWL+N+ GT EKL+P+ +W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVC+NGLMLLEIKD E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV EVQGYK+V
Sbjct 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ-YEYGTEDDYQGK 958
WS+AT+YLFD++GE +S MYCSFYPPDE+EE+ EEE T +EYGTEDDYQG
Sbjct 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
Query 959 PLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
PLEFGA++ ++ EEE+EEDWLDD ++Q+ E+
Sbjct 961 PLEFGASAETVRVEEEEEEDWLDDTTEQS-------------------EI-----EPEPE 996
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
VN F+GYLKLTDNV IK DIV+EA+ P V+VNAAN++LKHGGGVAGALNKA
Sbjct 997 PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKA 1056
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
TN AMQ ESDDYI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYENF
Sbjct 1057 TNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENF 1116
Query 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
N ++LLAPLLSAGIFGA P+ SL+VCV TVRT VY+AV DK LY+++V +L+ +
Sbjct 1117 NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPR- 1175
Query 1199 VEQKIAEIPKEEVKPFITESK---PSVEQRKQDDK-KIKACVEEVTTTLEETKFLTENLL 1254
E PK+E P +SK SV Q+ D K KIKAC++EVTTTLEETKFLT LL
Sbjct 1176 -----VEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLL 1230
Query 1255 LYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLA 1314
L+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML+
Sbjct 1231 LFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLS 1290
Query 1315 KALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWN 1374
+AL+KVP D YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSWN
Sbjct 1291 RALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWN 1350
Query 1375 LREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASL 1434
LREMLAHAEETRKLMP+C++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS+
Sbjct 1351 LREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASI 1410
Query 1435 INTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS 1494
I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSSS
Sbjct 1411 ITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSS 1470
Query 1495 KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVITF 1553
KT EEHF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGEV++
Sbjct 1471 KTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSL 1530
Query 1554 DNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSH 1613
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH +H
Sbjct 1531 DKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNH 1590
Query 1614 EGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNN 1673
EGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNN
Sbjct 1591 EGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN 1650
Query 1674 CYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMS 1733
CYL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM+
Sbjct 1651 CYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMT 1710
Query 1734 YLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQA 1793
+L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+ A
Sbjct 1711 HLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDA 1770
Query 1794 TKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALL 1853
T+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA L
Sbjct 1771 TQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHL 1830
Query 1854 TKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPID 1913
TK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPID
Sbjct 1831 TKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPID 1890
Query 1914 LVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYK 1973
LVP QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY+
Sbjct 1891 LVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYR 1950
Query 1974 HYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDA 2033
HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1951 HYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDT 2010
Query 2034 QGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHT 2093
QGMDNLACE +P SEEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+GH
Sbjct 2011 QGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHE 2070
Query 2094 DLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTT 2153
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + TT
Sbjct 2071 DLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITT 2130
Query 2154 TNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEA 2213
+N R RV NYMPY FTLL QLCTFT+STNSRI+AS+PTTIAKN+VKSV K CL+A
Sbjct 2131 SNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
Query 2214 SFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNS 2273
NY+KSP FSKL I +W LLLS+CLGSLI TAA GVL+SN G PSYC G RE YLNS
Sbjct 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNS 2250
Query 2274 TNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYIL 2333
+NVT +C GS PCS+CLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+L
Sbjct 2251 SNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYML 2310
Query 2334 FTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYV 2393
FT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY+
Sbjct 2311 FTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYI 2370
Query 2394 WKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCV 2453
WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC+
Sbjct 2371 WKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCL 2430
Query 2454 NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTY 2513
NCDTFC GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV VKNG++HLYFDKAGQKTY
Sbjct 2431 NCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTY 2490
Query 2514 ERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLD 2573
ERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES++KSASVYYSQLMCQPILLLD
Sbjct 2491 ERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLD 2550
Query 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
QALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF
Sbjct 2551 QALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTF 2610
Query 2634 ISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACID 2693
+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACID
Sbjct 2611 VSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACID 2670
Query 2694 CSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNV 2753
C+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV
Sbjct 2671 CNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNV 2730
Query 2754 VTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAID 2813
+TTKI+LKGGKIV+ K ++K TL+ + A + Y++ PVH +S H +++EIIGYKAI
Sbjct 2731 ITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQ 2790
Query 2814 GGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTI 2873
GVTRDI STD CFANKHA FD WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT+
Sbjct 2791 DGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTV 2850
Query 2874 LRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC 2933
LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYC
Sbjct 2851 LRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYC 2910
Query 2934 YDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
YDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2911 YDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE 2970
Query 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
G+C+STSGRWVLNN++YR+L GVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+
Sbjct 2971 VGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGII 3030
Query 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
AI+VTC AYYFM+FRR FGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYSV YLYLT
Sbjct 3031 AILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLT 3090
Query 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFS 3173
FY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNGV+FS
Sbjct 3091 FYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFS 3150
Query 3174 TFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCH 3233
TFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCH
Sbjct 3151 TFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCH 3210
Query 3234 LAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
LAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL
Sbjct 3211 LAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3270
Query 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
WLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LK
Sbjct 3271 WLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLK 3330
Query 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
VDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGF
Sbjct 3331 VDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGF 3390
Query 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
NIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYA
Sbjct 3391 NIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYA 3450
Query 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKE
Sbjct 3451 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
Query 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
LLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+
Sbjct 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLI 3570
Query 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMV
Sbjct 3571 LVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMV 3630
Query 3654 YMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMN 3713
YMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMN
Sbjct 3631 YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMN 3690
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITG
Sbjct 3691 VITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
NTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+
Sbjct 3751 NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKS 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ
Sbjct 3811 SIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPS 3953
LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPS
Sbjct 3871 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPS 3930
Query 3954 YAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 4013
YAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY
Sbjct 3931 YAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 3990
Query 4014 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4073
KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV
Sbjct 3991 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4050
Query 4074 IPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 4133
+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRA
Sbjct 4051 VPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRA 4110
Query 4134 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKW 4193
NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLKW
Sbjct 4111 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKW 4170
Query 4194 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4253
ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ
Sbjct 4171 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4230
Query 4254 AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
AGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE
Sbjct 4231 AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4290
Query 4314 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVC 4373
ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVC
Sbjct 4291 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 4350
Query 4374 GMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDK 4433
GMWKGYGCSCDQLREP++QSADA +FLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYN+K
Sbjct 4351 GMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEK 4410
Query 4434 VAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDF 4493
VAGFAKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+KDCPAVA HDF
Sbjct 4411 VAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDF 4470
Query 4494 FKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD 4553
FKFR+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD
Sbjct 4471 FKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD 4530
Query 4554 WYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGD 4613
WYDFVENPDILRVYANLGERVRQ+LLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWYDFGD
Sbjct 4531 WYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGD 4590
Query 4614 FIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLK 4673
F+Q PG GVP+VDSYYSLLMPILTLTRAL AESH+D DL KP IKWDLLKYDFTEERL
Sbjct 4591 FVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLC 4650
Query 4674 LFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV 4733
LFDRYFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV
Sbjct 4651 LFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV 4710
Query 4734 VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL 4793
VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL
Sbjct 4711 VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL 4770
Query 4794 TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP 4853
TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP
Sbjct 4771 TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP 4830
Query 4854 TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY 4913
TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY
Sbjct 4831 TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY 4890
Query 4914 EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA 4973
EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA
Sbjct 4891 EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA 4950
Query 4974 TRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARK 5033
TRGATVVIGTSKFYGGWHNMLKTVYSDVE PHLMGWDYPKCDRAMPNMLRIMASLVLARK
Sbjct 4951 TRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARK 5010
Query 5034 HTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT 5093
H TCC+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT
Sbjct 5011 HNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT 5070
Query 5094 ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDD 5153
ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV+EFYAYLRKHFSMMILSDD
Sbjct 5071 ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDD 5130
Query 5154 AVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK 5213
AVVC+NS YA+QGLVASIKNFK+VLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK
Sbjct 5131 AVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK 5190
Query 5214 QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF 5273
QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF
Sbjct 5191 QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF 5250
Query 5274 HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN 5333
HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN
Sbjct 5251 HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN 5310
Query 5334 SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS 5393
SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS
Sbjct 5311 SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS 5370
Query 5394 YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER 5453
YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER
Sbjct 5371 YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER 5430
Query 5454 LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK 5513
LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK
Sbjct 5431 LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK 5490
Query 5514 NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI 5573
NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI
Sbjct 5491 NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI 5550
Query 5574 TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC 5633
TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC
Sbjct 5551 TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC 5610
Query 5634 SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD 5693
SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD
Sbjct 5611 SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD 5670
Query 5694 IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM 5753
IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM
Sbjct 5671 IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM 5730
Query 5754 KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN 5813
KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN
Sbjct 5731 KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN 5790
Query 5814 RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT 5873
RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT
Sbjct 5791 RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT 5850
Query 5874 TETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF 5933
TETAHSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF
Sbjct 5851 TETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF 5910
Query 5934 KDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG 5993
KDCSK+ITGLHPTQAPTHLSVD KFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG
Sbjct 5911 KDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG 5970
Query 5994 YPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTP 6053
YPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAVPTGYVDT
Sbjct 5971 YPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTE 6030
Query 6054 NNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAH 6113
NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFVLWAH
Sbjct 6031 NNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAH 6090
Query 6114 GFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWG 6173
GFELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPFMIDVQQWG
Sbjct 6091 GFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWG 6150
Query 6174 FTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAA 6233
FTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDEL++N+A
Sbjct 6151 FTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSA 6210
Query 6234 CRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFY 6293
CRKVQHMVVK+ALLADKFPVLHDIGNPKAIKCVPQA+VEWKFYDAQPCSDKAYKIEELFY
Sbjct 6211 CRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFY 6270
Query 6294 SYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT 6353
SYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT
Sbjct 6271 SYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT 6330
Query 6354 PAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA 6413
PAFDKSAF NLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA
Sbjct 6331 PAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA 6390
Query 6414 NEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGE 6473
NEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQSLENVA+NVVNKGHFDG GE
Sbjct 6391 NEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGE 6450
Query 6474 VPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAA 6533
PVSIINN VYTKVDG+DVE+FENKTTLPVNVAFELWAKRNIKPVPE+KILNNLGVDIAA
Sbjct 6451 APVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAA 6510
Query 6534 NTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGV 6593
NTVIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ LTV FDGRV+GQVDLFRNARNGV
Sbjct 6511 NTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGV 6570
Query 6594 LITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQ 6653
LITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQSR+L+
Sbjct 6571 LITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLE 6630
Query 6654 EFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKES 6713
+FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR ++S
Sbjct 6631 DFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDS 6690
Query 6714 PFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVT 6773
P +LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV+SKVVKVT
Sbjct 6691 PLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVT 6750
Query 6774 IDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSAT 6833
IDY EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG++A
Sbjct 6751 IDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAV 6810
Query 6834 LPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL 6893
+PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL
Sbjct 6811 IPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL 6870
Query 6894 VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICG 6953
VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDP+TK+VTKENDSKEGFFTY+CG
Sbjct 6871 VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCG 6930
Query 6954 FIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKP 7013
FI+QKLALGGS+A+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NYLGKP
Sbjct 6931 FIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKP 6990
Query 7014 REQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLL 7073
+EQIDGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI SLL
Sbjct 6991 KEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLL 7050
Query 7074 SKGRLIIRENNRVVISSDVLVNN 7096
KGRLIIRENNRVV+SSD+LVNN
Sbjct 7051 EKGRLIIRENNRVVVSSDILVNN 7073
>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071
Score = 12924 bits (33542), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 6093/7104 (86%), Positives = 6580/7104 (93%), Gaps = 41/7104 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK GTCG+VE+EKGV
Sbjct 1 MESLVLGINEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKSGTCGIVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQ EQPYVFIKRSDA+ HGH + ELVAEL+G+QYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQPEQPYVFIKRSDAQGTDHGHRVRELVAELDGVQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHS+G DLKS+DLGDELGTDP ED+++NWNTKH SGV REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGVLRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A TRYVDNNFCGPDGYPLECIKDLLARAGK+ CTLSEQLD+I++KRGVYCCR+H HEIAW
Sbjct 181 ALTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCRDHGHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TCGYL
Sbjct 301 RSVYPVATPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVSEGPNTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + E+GPEHS A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSAADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF+LNEE+AIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFQLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+ +S+L+PL F S+A
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPIKGAWNIGQHRSVLTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIFSRTL+ A +S+ LQ+AA+TILD IS+ SLRL+DAM++TS+L TN++++MAY
Sbjct 541 AGVIRSIFSRTLDAANHSIPDLQRAAVTILDSISEQSLRLVDAMVYTSNLLTNSVIIMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ TSQWL+N+ T EKL+P+ W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 VTGGLVQQTSQWLSNLLDTTVEKLRPIFAWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNIKDCVKCFVDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAVVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVCINGLMLLEIK E+YCAL+P ++ TNN F LKGGAPTK VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCINGLMLLEIKANEQYCALSPGLLATNNVFRLKGGAPTKGVTFGEDTVVEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEP--STQYEYGTEDDYQG 957
WS+AT+YLFD+SGE KL+S MYCSFYPPDE+E+ + EEEE + ++EYGTE+DY+G
Sbjct 901 WSVATFYLFDDSGEEKLSSRMYCSFYPPDEEEDCEEYEEEEEVSERTCEHEYGTEEDYKG 960
Query 958 KPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELT 1017
PLEFGA++ +Q EE++EEDWLDD + +
Sbjct 961 LPLEFGASTDIIQVEEQEEEDWLDDAVEAEPEPE-------------------------- 994
Query 1018 PVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
+ VN +GYLKLTDNV IK DIVEEA+ P V+VNAAN++LKHGGGVAGALNK
Sbjct 995 -PLHEEPVNQLTGYLKLTDNVAIKCVDIVEEAQNANPMVIVNAANIHLKHGGGVAGALNK 1053
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
ATN AMQ ESD YI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYEN
Sbjct 1054 ATNGAMQKESDHYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYEN 1113
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK 1197
FN ++LLAPLLSAGIFGA P+ SL++CV TVRT VY+ V DK LY+++V +L+ K
Sbjct 1114 FNSQDILLAPLLSAGIFGAKPLQSLQMCVQTVRTQVYIVVNDKVLYEQVVMDYLDSLKPK 1173
Query 1198 QVEQKIAEIPKEEVKP---FITESKPSVEQRKQDDK-KIKACVEEVTTTLEETKFLTENL 1253
E PK+EV P + + SV Q+ D K KIKAC++EVTTTLEETKFLT L
Sbjct 1174 ------VEAPKQEVLPKAEYPKVDEKSVVQKTIDVKPKIKACIDEVTTTLEETKFLTNKL 1227
Query 1254 LLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEML 1313
LL+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML
Sbjct 1228 LLFTDINGKLYQDSKNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEML 1287
Query 1314 AKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSW 1373
++AL+KVP + YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSW
Sbjct 1288 SRALKKVPINEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSETPNAKEEILGTVSW 1347
Query 1374 NLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVAS 1433
NLREMLAHAEETRKLMPVC++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS
Sbjct 1348 NLREMLAHAEETRKLMPVCMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVAS 1407
Query 1434 LINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSS 1493
+I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSS
Sbjct 1408 IITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAIVSVSSPDAVTTYNGYLTSS 1467
Query 1494 SKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVIT 1552
SKT E+HF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRG+K VY+T +P FHLDGEV+
Sbjct 1468 SKTSEDHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGEKIVYHTLESPVKFHLDGEVLP 1527
Query 1553 FDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNS 1612
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQ GPTYL+GADVTKIKPH +
Sbjct 1528 LDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQLGPTYLEGADVTKIKPHVN 1587
Query 1613 HEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADN 1672
HEGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADN
Sbjct 1588 HEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADN 1647
Query 1673 NCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETM 1732
NCYL++ LL LQQIE+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM
Sbjct 1648 NCYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETM 1707
Query 1733 SYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQ 1792
++L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+
Sbjct 1708 THLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKMGVSIPCVCGRD 1767
Query 1793 ATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGAL 1852
AT+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA
Sbjct 1768 ATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAH 1827
Query 1853 LTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPI 1912
LTK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPI
Sbjct 1828 LTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPI 1887
Query 1913 DLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDY 1972
DL+P QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY
Sbjct 1888 DLIPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDY 1947
Query 1973 KHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSED 2032
+HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1948 RHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVED 2007
Query 2033 AQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGH 2092
QGMDNLACE +P EEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+ H
Sbjct 2008 TQGMDNLACESQQPTPEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELDH 2067
Query 2093 TDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVST 2152
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + T
Sbjct 2068 EDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWGKILAYVKPFLGQAAVT 2127
Query 2153 TTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLE 2212
T+N R + R+ NYMPY TLL QLCTFT+STNSRI+AS+PTTIAKN+V+ + + CL+
Sbjct 2128 TSNCAKRLVQRMFNNYMPYVLTLLFQLCTFTKSTNSRIRASLPTTIAKNSVRGIVRLCLD 2187
Query 2213 ASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLN 2272
A NY+KSP FSKL I +W LLLS+CLGSLIY TAALGVL+SN G PSYC+G RE YLN
Sbjct 2188 AGINYVKSPKFSKLFTIAMWLLLLSICLGSLIYVTAALGVLLSNFGAPSYCSGVRESYLN 2247
Query 2273 STNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYI 2332
S+NVT +C GS PCSVCLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEWF AY+
Sbjct 2248 SSNVTTMDFCEGSFPCSVCLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWFFAYM 2307
Query 2333 LFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYY 2392
LFT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY
Sbjct 2308 LFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYY 2367
Query 2393 VWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNC 2452
+WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC
Sbjct 2368 IWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNC 2427
Query 2453 VNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKT 2512
+NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSY+VDSV VKNG++HLYFDKAGQKT
Sbjct 2428 LNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAGQKT 2487
Query 2513 YERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLL 2572
YERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES+AKSASVYYSQLMCQPILLL
Sbjct 2488 YERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPILLL 2547
Query 2573 DQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLST 2632
DQALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLST
Sbjct 2548 DQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLST 2607
Query 2633 FISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACI 2692
F+SA+RQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACI
Sbjct 2608 FVSASRQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACI 2667
Query 2693 DCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVN 2752
DC+ARHINAQVA+SHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVN
Sbjct 2668 DCNARHINAQVARSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVN 2727
Query 2753 VVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAI 2812
V+TTKI+LKGGKIV+ W K ++K TL+ + A + Y++ PVH++S H +++EIIGYKAI
Sbjct 2728 VITTKISLKGGKIVSTWFKIMLKATLLCVLAALVCYIVMPVHILSVHGGYTNEIIGYKAI 2787
Query 2813 DGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGT 2872
GVTRDI STD CFANKHA FD+WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT
Sbjct 2788 QDGVTRDIVSTDDCFANKHAGFDSWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGT 2847
Query 2873 ILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPY 2932
+LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DF+TSACVLAAECTIFKDA GKPVPY
Sbjct 2848 VLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFSTSACVLAAECTIFKDAMGKPVPY 2907
Query 2933 CYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERS 2992
CYDTN+LEGS++Y LRPDTRYVLMDGSIIQFPN YLEGSVRVVTTFD+EYCRHGTCERS
Sbjct 2908 CYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNAYLEGSVRVVTTFDAEYCRHGTCERS 2967
Query 2993 EAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGI 3052
EAG+C+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI
Sbjct 2968 EAGICLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGI 3027
Query 3053 VAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYL 3112
+AI+VTC AYYFM+FRRAFGEY+HVVA N LFLMSFT+LCL P YSFLPGVYSV YLYL
Sbjct 3028 IAILVTCAAYYFMKFRRAFGEYNHVVAANAPLFLMSFTILCLAPAYSFLPGVYSVFYLYL 3087
Query 3113 TFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSF 3172
TFY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KHF+WFF+NYL++RVVFNGV+F
Sbjct 3088 TFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHFHWFFNNYLRKRVVFNGVTF 3147
Query 3173 STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACC 3232
STFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACC
Sbjct 3148 STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACC 3207
Query 3233 HLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG 3292
HLAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG
Sbjct 3208 HLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG 3267
Query 3293 LWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKL 3352
LWLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+L
Sbjct 3268 LWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRL 3327
Query 3353 KVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVG 3412
KVDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVG
Sbjct 3328 KVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVG 3387
Query 3413 FNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLY 3472
FNIDYDCVSFCYMHHMELPT VHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLY
Sbjct 3388 FNIDYDCVSFCYMHHMELPTEVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLY 3447
Query 3473 AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLK 3532
AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LK
Sbjct 3448 AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALK 3507
Query 3533 ELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLL 3592
ELLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ KR +KGTHHW+LLT LTSLL
Sbjct 3508 ELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKRIVKGTHHWMLLTFLTSLL 3567
Query 3593 VLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNM 3652
+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNM
Sbjct 3568 ILVQSTQWSLFFFVYENAFLPFTLGIMAVAACAMLLVKHKHAFLCLFLLPSLATVAYFNM 3627
Query 3653 VYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLM 3712
VYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL+LMTARTVYDD ARRVWTLM
Sbjct 3628 VYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVWTLM 3687
Query 3713 NVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFIT 3772
NV+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FIT
Sbjct 3688 NVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFIT 3747
Query 3773 GNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK 3832
GNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK
Sbjct 3748 GNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK 3807
Query 3833 NSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV 3892
+SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV
Sbjct 3808 SSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV 3867
Query 3893 QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP 3952
QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP
Sbjct 3868 QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP 3927
Query 3953 SYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQM 4012
SYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR+AAMQRKLEKMADQAMTQM
Sbjct 3928 SYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRNAAMQRKLEKMADQAMTQM 3987
Query 4013 YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV 4072
YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV
Sbjct 3988 YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV 4047
Query 4073 VIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALR 4132
V+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+M+NS NLAWPLIVTALR
Sbjct 4048 VVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMENSSNLAWPLIVTALR 4107
Query 4133 ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLK 4192
ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLK
Sbjct 4108 ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLK 4167
Query 4193 WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRL 4252
WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL+FIKGLNNLNRGMVLGSLAATVRL
Sbjct 4168 WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLHFIKGLNNLNRGMVLGSLAATVRL 4227
Query 4253 QAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP 4312
QAGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP
Sbjct 4228 QAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP 4287
Query 4313 EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTV 4372
EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTV
Sbjct 4288 EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTV 4347
Query 4373 CGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYND 4432
CGMWKGYGCSCDQLREPM+QSADA +FLNRVCGVSAARLTPCGTG STDVVYRAFDIYN+
Sbjct 4348 CGMWKGYGCSCDQLREPMMQSADASTFLNRVCGVSAARLTPCGTGISTDVVYRAFDIYNE 4407
Query 4433 KVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHD 4492
KVAGFAKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+KDCPAVA HD
Sbjct 4408 KVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHD 4467
Query 4493 FFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKK 4552
FFKFR+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKK
Sbjct 4468 FFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKK 4527
Query 4553 DWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFG 4612
DWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWYDFG
Sbjct 4528 DWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFG 4587
Query 4613 DFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERL 4672
DF+Q PG GVP+VDSYYSLLMPILTLTRAL AESH+D DL KP IKWDLLKYDFT ERL
Sbjct 4588 DFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTAERL 4647
Query 4673 KLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPF 4732
LFDRYFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPF
Sbjct 4648 CLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPF 4707
Query 4733 VVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAA 4792
VVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAA
Sbjct 4708 VVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAA 4767
Query 4793 LTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNL 4852
LTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNL
Sbjct 4768 LTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNL 4827
Query 4853 PTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMS 4912
PTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMS
Sbjct 4828 PTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMS 4887
Query 4913 YEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIA 4972
YEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIA
Sbjct 4888 YEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIA 4947
Query 4973 ATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLAR 5032
ATRGATVVIGTSKFYGGWHNMLKTVYSDVE PHLMGWDYPKCDRAMPNMLRIMASLVLAR
Sbjct 4948 ATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLAR 5007
Query 5033 KHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAV 5092
KH+TCC+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAV
Sbjct 5008 KHSTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAV 5067
Query 5093 TANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSD 5152
TANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV EFYAYLRKHFSMMILSD
Sbjct 5068 TANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVGEFYAYLRKHFSMMILSD 5127
Query 5153 DAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLV 5212
DAVVC+NS YA+QGLVASIKNFK+VLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLV
Sbjct 5128 DAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLV 5187
Query 5213 KQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADV 5272
KQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADV
Sbjct 5188 KQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADV 5247
Query 5273 FHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLC 5332
FHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLC
Sbjct 5248 FHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLC 5307
Query 5333 NSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGM 5392
NSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGM
Sbjct 5308 NSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGM 5367
Query 5393 SYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTE 5452
SYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTE
Sbjct 5368 SYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTE 5427
Query 5453 RLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVT 5512
RLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVT
Sbjct 5428 RLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVT 5487
Query 5513 KNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVR 5572
KNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLN+GDYFVLTSHTVMPLSAPTLVPQEHYVR
Sbjct 5488 KNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNIGDYFVLTSHTVMPLSAPTLVPQEHYVR 5547
Query 5573 ITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTA 5632
ITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTA
Sbjct 5548 ITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTA 5607
Query 5633 CSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTA 5692
CSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTA
Sbjct 5608 CSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTA 5667
Query 5693 DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRL 5752
DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRL
Sbjct 5668 DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRL 5727
Query 5753 MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAI 5812
MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHK+KSAQCFKMFYKGVITHDVSSAI
Sbjct 5728 MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKEKSAQCFKMFYKGVITHDVSSAI 5787
Query 5813 NRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQ 5872
NRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQ
Sbjct 5788 NRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQ 5847
Query 5873 TTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGL 5932
TTETAHSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLE+PRRNVATLQAENVTGL
Sbjct 5848 TTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEVPRRNVATLQAENVTGL 5907
Query 5933 FKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVN 5992
FKDCSK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVN
Sbjct 5908 FKDCSKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVN 5967
Query 5993 GYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDT 6052
GYPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVA+PTGYVDT
Sbjct 5968 GYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAIPTGYVDT 6027
Query 6053 PNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWA 6112
NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFVLWA
Sbjct 6028 ENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWA 6087
Query 6113 HGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQW 6172
HGFELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPFMIDVQQW
Sbjct 6088 HGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQW 6147
Query 6173 GFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINA 6232
GFTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDELKIN+
Sbjct 6148 GFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELKINS 6207
Query 6233 ACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELF 6292
ACRKVQHMVVK+ALLADKFPVLHDIGNPKAIKCVPQA+VEWKFYDAQPCSDKAYKIEELF
Sbjct 6208 ACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELF 6267
Query 6293 YSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFH 6352
YSYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKHAFH
Sbjct 6268 YSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFH 6327
Query 6353 TPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHH 6412
TPAFDKSAF NLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHH
Sbjct 6328 TPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHH 6387
Query 6413 ANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQG 6472
ANEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQSLENVA+NVVNKGHFDGQ G
Sbjct 6388 ANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGQAG 6447
Query 6473 EVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIA 6532
E PVSIINN VYTKVDG DVE+FENKTTLPVNVAFELWAKRNIK VPE+KILNNLGVDIA
Sbjct 6448 ETPVSIINNAVYTKVDGFDVEIFENKTTLPVNVAFELWAKRNIKSVPEIKILNNLGVDIA 6507
Query 6533 ANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNG 6592
ANTVIWD+KR+AP H+STIGVC+MTDIAKKPTE+ C+ LTV FDGRV+GQVDLFRNARNG
Sbjct 6508 ANTVIWDHKREAPVHMSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNG 6567
Query 6593 VLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNL 6652
VLITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQSR+L
Sbjct 6568 VLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDL 6627
Query 6653 QEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKE 6712
++FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR ++
Sbjct 6628 EDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSRD 6687
Query 6713 SPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKV 6772
SP +LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKV
Sbjct 6688 SPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKV 6747
Query 6773 TIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSA 6832
TIDY EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG++A
Sbjct 6748 TIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENA 6807
Query 6833 TLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTL 6892
+PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTL
Sbjct 6808 VIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTL 6867
Query 6893 LVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYIC 6952
LVDSDLNDFVSDADSTLIGDCATVHTANKWDLI+SDMYDPK K+VTKENDSKEGFFTY+C
Sbjct 6868 LVDSDLNDFVSDADSTLIGDCATVHTANKWDLIVSDMYDPKAKHVTKENDSKEGFFTYLC 6927
Query 6953 GFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGK 7012
GFI+QKLALGGSVA+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NYLGK
Sbjct 6928 GFIKQKLALGGSVAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGVNYLGK 6987
Query 7013 PREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSL 7072
P+EQIDGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI SL
Sbjct 6988 PKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSL 7047
Query 7073 LSKGRLIIRENNRVVISSDVLVNN 7096
L KGRLIIRENNRVV+SSD+LVNN
Sbjct 7048 LEKGRLIIRENNRVVVSSDILVNN 7071
>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079
Score = 12917 bits (33522), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 6093/7107 (86%), Positives = 6568/7107 (92%), Gaps = 39/7107 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESL G +EKTHVQLSLPVLQVRDVLVRGFGDSVEE L+EAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLALGVSEKTHVQLSLPVLQVRDVLVRGFGDSVEEALAEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA+ HG+ +VELVAEL+GIQYGRSG TLGVLVPHVGE PVAYR
Sbjct 61 LPQLEQPYVFIKRSDAQGTNHGYKVVELVAELDGIQYGRSGTTLGVLVPHVGETPVAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLG ELGTDP ED+++NWNTKH GV REL+RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGVELGTDPIEDYEQNWNTKHGGGVLRELIRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A+TRYVDNNFCGPDGYPLECIKDLLARAGK+ CTLSEQLD+I++KRGVYCCREHEHEI W
Sbjct 181 AFTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERSEKSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSEKSYERQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + EVGPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PANAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIG +HTG+ G+ E LN++L+EIL +++VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASANIGASHTGITGDNVETLNEDLMEILNRDRVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SAST AFV+TVKGLDYK FK IVESCGNFKVT+G+AKKGAWNIG++KSIL+PLY F S+A
Sbjct 481 SASTCAFVDTVKGLDYKTFKDIVESCGNFKVTRGRAKKGAWNIGQEKSILTPLYGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIF+R L+TA +S+ LQ+AAITILDGIS+ SLRLIDAM++TSDL TN+++VMAY
Sbjct 541 AGVIRSIFTRALDTANHSIPDLQRAAITILDGISEQSLRLIDAMVYTSDLLTNSVIVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ +QWL+N+ GT +KLKPV W+E K G+EFLRD WEI+KF+ T +IV
Sbjct 601 VTGGLVQQITQWLSNMLGTTVDKLKPVFTWVEAKLSAGIEFLRDAWEILKFLVTGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + +KE V+ F ++NK L +C D +II GAKL+ LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNLKECVKAFLDVLNKALEMCIDQVIIAGAKLRTLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPL+APKE+ F EG++ T +EEVVLK G+L+ LE P ++G
Sbjct 721 IRGKEQLQLLMPLRAPKEVTFFEGDSHDTVFTSEEVVLKNGELEALETPVDSFTNGAVIG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVC+NGLMLLE+KD E+YCAL+P ++ TNN F+LKGGAP K VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCVNGLMLLELKDKEQYCALSPGLLATNNVFSLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 KITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ--YEYGTEDDYQG 957
WS+AT+YLFD++GE KL+S MYCSFYPPDE+E+ + E+EE P +EYGTEDDY+G
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCEEYEDEEEIPEETCEHEYGTEDDYKG 960
Query 958 KPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELT 1017
PLEFGA++ + QQ +++ + + E
Sbjct 961 LPLEFGAST----------------EIQQVDEEEEEDWLEEAIAAKPEPEPL-------- 996
Query 1018 PVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
VN F+GYLKLTDNV IK DIV+EA+ KPTV+VNAANV+LKHGGGVAGALNK
Sbjct 997 ---PEEPVNQFTGYLKLTDNVAIKCVDIVKEAQHAKPTVIVNAANVHLKHGGGVAGALNK 1053
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
ATN AMQ ESDDYI NGPL VGGSC+LSGHNLAK C+HVVGPN+N GED+QLLK+AY N
Sbjct 1054 ATNGAMQQESDDYIKKNGPLTVGGSCLLSGHNLAKKCMHVVGPNLNAGEDVQLLKAAYAN 1113
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK 1197
FN +VLLAPLLSAGIFGA P+ SL++CV+TVRT VY AV D++LYD +V +L+ K
Sbjct 1114 FNSQDVLLAPLLSAGIFGAKPLQSLKMCVETVRTQVYFAVNDQDLYDHVVLGYLDSLKPK 1173
Query 1198 QVE---QKIAEIPKEEVKPFITESKPSVEQ----RKQDDKKIKACVEEVTTTLEETKFLT 1250
VE Q+ E+ ++ +T+ +E+ K D K KA +EEV T+LEETKFLT
Sbjct 1174 -VETPTQENLELKEQPAVETLTQENLELEELPVIEKPVDVKFKARIEEVNTSLEETKFLT 1232
Query 1251 ENLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTT 1310
LLL+ DING L+ DS ++ D+ FL+KDAPYIVGDV+ G +T V+IP KKAGGTT
Sbjct 1233 SRLLLFADINGKLYQDSQNMLRGEDMFFLEKDAPYIVGDVISSGDITCVIIPAKKAGGTT 1292
Query 1311 EMLAKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGT 1370
EMLAKAL+KVP YITTYPGQG GYT+EEAKT L+KCKS FY+LPS N+K+EILGT
Sbjct 1293 EMLAKALKKVPVSEYITTYPGQGCAGYTLEEAKTALRKCKSVFYVLPSKTPNDKEEILGT 1352
Query 1371 VSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTT 1430
VSWNLREMLAHAEETRKLM +C++ KA++STI R+YKGIK+QEG+VDYG RF+FYTSK
Sbjct 1353 VSWNLREMLAHAEETRKLMLICMDVKALMSTIHRRYKGIKVQEGIVDYGVRFFFYTSKEP 1412
Query 1431 VASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYL 1490
VAS+I LN LNE LVTMP+GYVTHGLNLEEAAR MRSLK PA VSVSSPDAVT YNGYL
Sbjct 1413 VASIITKLNLLNEPLVTMPIGYVTHGLNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYL 1472
Query 1491 TSSSKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGE 1549
TSSSKT EEHFIET+SLAG Y+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGE
Sbjct 1473 TSSSKTSEEHFIETVSLAGMYRDWSYSGQRTELGVEFLKRGDKVVYHTVGSPIQFHLDGE 1532
Query 1550 VITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKP 1609
V+ D LK+LLSLREVRTIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKP
Sbjct 1533 VLLLDKLKSLLSLREVRTIKVFTTVDNTNLHTQIVDMSMTYGQQFGPTYLDGADVTKIKP 1592
Query 1610 HNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKW 1669
H HEGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQ+ GLTSIKW
Sbjct 1593 HAKHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQIGGLTSIKW 1652
Query 1670 ADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVR 1729
ADNNCYL++ LL LQQIE+KFN PALQ+AYYRARAG+AANFCALILAY N+TVGELGDVR
Sbjct 1653 ADNNCYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAYSNRTVGELGDVR 1712
Query 1730 ETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTC 1789
ETM++L QHANL+S KRVLNVVCKTCGQ+ TTL GVEAVMYMGTLSYE+ K GV IPC C
Sbjct 1713 ETMTHLLQHANLESAKRVLNVVCKTCGQKSTTLTGVEAVMYMGTLSYEELKTGVTIPCIC 1772
Query 1790 GKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCID 1849
G+ AT+YLVQQES FVMMSAPP++Y L+ G F CA+EYTG+YQCGHY H+T KETLY ID
Sbjct 1773 GRDATQYLVQQESSFVMMSAPPSEYTLQQGAFLCANEYTGSYQCGHYTHVTVKETLYRID 1832
Query 1850 GALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTE 1909
GA LTK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV+ TEI PKLD YYKKDN+Y+TE
Sbjct 1833 GAYLTKMSEYKGPVTDVFYKEISYTTTIKPVSYKLDGVIYTEIQPKLDEYYKKDNAYYTE 1892
Query 1910 QPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVA 1969
QPIDLVP QP PNASFDNFK C N KFADDLNQ+TG+KKPASREL VTFFPDLNGDVVA
Sbjct 1893 QPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFKKPASRELSVTFFPDLNGDVVA 1952
Query 1970 IDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLK 2029
IDY+HY+ SFKKGAKLLHKPI+WH+N TNK TYKPNTWC+RCLWSTKPVETSNSF+VL+
Sbjct 1953 IDYRHYSASFKKGAKLLHKPIIWHINQTTNKTTYKPNTWCLRCLWSTKPVETSNSFEVLE 2012
Query 2030 SEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEE 2089
ED QGMDNLACE P SEEVVENPTIQK+V+EC+VKT EVVG++ILKP+ +K+T+E
Sbjct 2013 VEDTQGMDNLACESQTPTSEEVVENPTIQKEVIECDVKTIEVVGNVILKPSEEGVKVTQE 2072
Query 2090 VGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKV 2149
+GH DLMAAYV+ +S+TIKKPNELS LGL+TLATHG AA+NSVPW I Y KPFL +
Sbjct 2073 LGHEDLMAAYVEETSITIKKPNELSLALGLRTLATHGAAAINSVPWSKILAYVKPFLGQA 2132
Query 2150 VSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKF 2209
TTTN + RC+ RV NYMPY TLL QLCTFTRSTNSRI+AS+PTTIAKN+VKSV K
Sbjct 2133 AVTTTNCIKRCVQRVFNNYMPYVITLLFQLCTFTRSTNSRIRASLPTTIAKNSVKSVAKL 2192
Query 2210 CLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREG 2269
CL+ NY+KSP FSKL I +W LLLS+CLGSLIY TAA GVL+SNLG+PSYC G RE
Sbjct 2193 CLDVCINYVKSPKFSKLFTIAMWLLLLSICLGSLIYVTAAFGVLLSNLGIPSYCDGVRES 2252
Query 2270 YLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFL 2329
Y+NS+NVT +C GS CSVCL+GLDSLD+YP+LETIQ+TISS+K DLT+ GL AEWFL
Sbjct 2253 YVNSSNVTTMDFCEGSFLCSVCLNGLDSLDSYPALETIQVTISSYKLDLTSLGLAAEWFL 2312
Query 2330 AYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFAS 2389
AY+LFT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFA
Sbjct 2313 AYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFAF 2372
Query 2390 FYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHN 2449
YYVWKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HN
Sbjct 2373 CYYVWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKAHN 2432
Query 2450 WNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAG 2509
WNC+NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSY+VDSV VKNG++HLYFDKAG
Sbjct 2433 WNCLNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAG 2492
Query 2510 QKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPI 2569
QKTYERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES+AKSASVYYSQLMCQPI
Sbjct 2493 QKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPI 2552
Query 2570 LLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNV 2629
LLLDQALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD V
Sbjct 2553 LLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGV 2612
Query 2630 LSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLG 2689
LSTF+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLG
Sbjct 2613 LSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLG 2672
Query 2690 ACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQ 2749
ACIDC+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQ
Sbjct 2673 ACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQ 2732
Query 2750 VVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGY 2809
VVN +TTKI+LKGGKIV+ W K ++K TL+ + A Y+I PVH +S H +++EIIGY
Sbjct 2733 VVNAITTKISLKGGKIVSTWFKLMLKATLLCVLAALFCYIIMPVHSLSVHDGYTNEIIGY 2792
Query 2810 KAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGL 2869
KAI GVTRDI +TD CFANKHA FD+WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGL
Sbjct 2793 KAIQDGVTRDIMATDDCFANKHAGFDSWFSQRGGSYRNDKSCPVVAAIITREIGFIVPGL 2852
Query 2870 PGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKP 2929
PGT+LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKP
Sbjct 2853 PGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKP 2912
Query 2930 VPYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTC 2989
VPYCYDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTC
Sbjct 2913 VPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTC 2972
Query 2990 ERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVA 3049
ERSEAGVC+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VA
Sbjct 2973 ERSEAGVCLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVA 3032
Query 3050 GGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIY 3109
GGI+AI+VTC AYYFM+FRRAFGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYS+ Y
Sbjct 3033 GGIIAILVTCAAYYFMKFRRAFGEYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFY 3092
Query 3110 LYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNG 3169
LYLTFY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNG
Sbjct 3093 LYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNG 3152
Query 3170 VSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREA 3229
V+FSTFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREA
Sbjct 3153 VTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREA 3212
Query 3230 ACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT 3289
ACCHLAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT
Sbjct 3213 ACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT 3272
Query 3290 LNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCV 3349
LNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+
Sbjct 3273 LNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCL 3332
Query 3350 LKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCG 3409
L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN+TIKGSFLNGSCG
Sbjct 3333 LRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNYTIKGSFLNGSCG 3392
Query 3410 SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLA 3469
SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLA
Sbjct 3393 SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLA 3452
Query 3470 WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA 3529
WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA
Sbjct 3453 WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA 3512
Query 3530 SLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILT 3589
+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LT
Sbjct 3513 ALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLT 3572
Query 3590 SLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAY 3649
SLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAY
Sbjct 3573 SLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAY 3632
Query 3650 FNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVW 3709
FNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL+LMTARTVYDD ARRVW
Sbjct 3633 FNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVW 3692
Query 3710 TLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIF 3769
TLMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+
Sbjct 3693 TLMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLL 3752
Query 3770 FITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL 3829
FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL
Sbjct 3753 FITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL 3812
Query 3830 PPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA 3889
PPK+SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA
Sbjct 3813 PPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA 3872
Query 3890 QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFS 3949
QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFS
Sbjct 3873 QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFS 3932
Query 3950 SLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM 4009
SLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM
Sbjct 3933 SLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM 3992
Query 4010 TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK 4069
TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK
Sbjct 3993 TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK 4052
Query 4070 LMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVT 4129
LMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNS NLAWPLIVT
Sbjct 4053 LMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSQNLAWPLIVT 4112
Query 4130 ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQ 4189
ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD Q
Sbjct 4113 ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQ 4172
Query 4190 DLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAAT 4249
DLKWARFPKSDGTGTIYTELEPPCRFVTDTP+GPKVKYLYFIKGLNNLNRGMVLGSLAAT
Sbjct 4173 DLKWARFPKSDGTGTIYTELEPPCRFVTDTPRGPKVKYLYFIKGLNNLNRGMVLGSLAAT 4232
Query 4250 VRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT 4309
VRLQAGNATEVPANS VLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT
Sbjct 4233 VRLQAGNATEVPANSAVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT 4292
Query 4310 VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIP TCANDPVGFTLKNTV
Sbjct 4293 VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPATCANDPVGFTLKNTV 4352
Query 4370 CTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDI 4429
CTVCG WKGYGCSCDQLREPM+QSADA +FLNRVCGVSAARLTPCGTGTSTDVVYRAFDI
Sbjct 4353 CTVCGTWKGYGCSCDQLREPMMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDI 4412
Query 4430 YNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVA 4489
YN++VAGFAKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+K+CPAVA
Sbjct 4413 YNERVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKECPAVA 4472
Query 4490 KHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYF 4549
HDFFKFR+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYF
Sbjct 4473 VHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYF 4532
Query 4550 NKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWY 4609
NKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWY
Sbjct 4533 NKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWY 4592
Query 4610 DFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTE 4669
DFGDF+Q PG GVP+VDSYYSLLMPILTLT+AL AESH+D DL KP IKWDLLKYDFTE
Sbjct 4593 DFGDFVQVAPGCGVPIVDSYYSLLMPILTLTKALAAESHMDADLAKPLIKWDLLKYDFTE 4652
Query 4670 ERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDG 4729
ERL LFDRYFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDG
Sbjct 4653 ERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDG 4712
Query 4730 VPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFS 4789
VPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFS
Sbjct 4713 VPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFS 4772
Query 4790 VAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYR 4849
VAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYR
Sbjct 4773 VAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYR 4832
Query 4850 YNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYD 4909
YNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYD
Sbjct 4833 YNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYD 4892
Query 4910 SMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLK 4969
SMSYEDQD LFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLK
Sbjct 4893 SMSYEDQDVLFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLK 4952
Query 4970 SIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLV 5029
SIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE PHLMGWDYPKCDRAMPNMLRIMASLV
Sbjct 4953 SIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLV 5012
Query 5030 LARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNIC 5089
LARKH+TCC+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNIC
Sbjct 5013 LARKHSTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNIC 5072
Query 5090 QAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMI 5149
QAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV+EFYAYLRKHFSMMI
Sbjct 5073 QAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMI 5132
Query 5150 LSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHT 5209
LSDDAVVC+NS YA+QGLVASIKNFK+V YYQNNVFMSEAKCWTETDLTKGPHEFCSQHT
Sbjct 5133 LSDDAVVCYNSNYAAQGLVASIKNFKAVHYYQNNVFMSEAKCWTETDLTKGPHEFCSQHT 5192
Query 5210 MLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEY 5269
MLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEY
Sbjct 5193 MLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEY 5252
Query 5270 ADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGAC 5329
ADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGAC
Sbjct 5253 ADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGAC 5312
Query 5330 VLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYL 5389
VLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYL
Sbjct 5313 VLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYL 5372
Query 5390 GGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANT 5449
GGMSYYCK HKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANT
Sbjct 5373 GGMSYYCKLHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANT 5432
Query 5450 CTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGY 5509
CTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGY
Sbjct 5433 CTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGY 5492
Query 5510 RVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEH 5569
RVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEH
Sbjct 5493 RVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEH 5552
Query 5570 YVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIV 5629
YVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIV
Sbjct 5553 YVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIV 5612
Query 5630 YTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPE 5689
YTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPE
Sbjct 5613 YTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPE 5672
Query 5690 TTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV 5749
TTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV
Sbjct 5673 TTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV 5732
Query 5750 CRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVS 5809
CRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHK+KSAQCFKMFYKGVITHDVS
Sbjct 5733 CRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKEKSAQCFKMFYKGVITHDVS 5792
Query 5810 SAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVI 5869
SAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVI
Sbjct 5793 SAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVI 5852
Query 5870 FTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENV 5929
FTQTTETAHSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLE+PRRNVATLQAENV
Sbjct 5853 FTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEVPRRNVATLQAENV 5912
Query 5930 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNY 5989
TGLFKDCSK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNY
Sbjct 5913 TGLFKDCSKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNY 5972
Query 5990 QVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGY 6049
QVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAVPTGY
Sbjct 5973 QVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGY 6032
Query 6050 VDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFV 6109
VDT NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFV
Sbjct 6033 VDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFV 6092
Query 6110 LWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDV 6169
LWAHGFELTSMKYFVKIGPERTCCLCDRRATCFST+SDTYACW+HS+GFDYVYNPFMIDV
Sbjct 6093 LWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTSSDTYACWNHSVGFDYVYNPFMIDV 6152
Query 6170 QQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELK 6229
QQWGFTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDELK
Sbjct 6153 QQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELK 6212
Query 6230 INAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIE 6289
INAACRKVQHMVVK+ALLADKF VLHDIGNPKAIKCVPQA+V+WKFYDAQPCSDKAYKIE
Sbjct 6213 INAACRKVQHMVVKSALLADKFSVLHDIGNPKAIKCVPQAEVDWKFYDAQPCSDKAYKIE 6272
Query 6290 ELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKH 6349
ELFYSYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKH
Sbjct 6273 ELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKH 6332
Query 6350 AFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVC 6409
AFHTPAFDKSAF LKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVC
Sbjct 6333 AFHTPAFDKSAFTYLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVC 6392
Query 6410 RHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDG 6469
R HANEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQSLENVA+NVVNKGHFDG
Sbjct 6393 RRHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDG 6452
Query 6470 QQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGV 6529
Q GE PVSIINN VYTKVDG DVE+FENKTTLPVNVAFELWAKRNIKPVPE+KILNNLGV
Sbjct 6453 QIGEAPVSIINNAVYTKVDGNDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGV 6512
Query 6530 DIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNA 6589
DIAANTVIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ LTV FDGRV+GQVDLFRNA
Sbjct 6513 DIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNA 6572
Query 6590 RNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQS 6649
RNGVLITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQS
Sbjct 6573 RNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQS 6632
Query 6650 RNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKR 6709
R+L++FKPRS+ME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR
Sbjct 6633 RDLEDFKPRSKMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKR 6692
Query 6710 FKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKV 6769
++SP +LEDFIP DSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV+SKV
Sbjct 6693 SQDSPLKLEDFIPTDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKV 6752
Query 6770 VKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYG 6829
VKVTIDY EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG
Sbjct 6753 VKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYG 6812
Query 6830 DSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPT 6889
++A +PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPT
Sbjct 6813 ENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPT 6872
Query 6890 GTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFT 6949
G LLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTK+VTKENDSKEGFFT
Sbjct 6873 GALLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKHVTKENDSKEGFFT 6932
Query 6950 YICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNY 7009
Y+CGFI+QKLALGGSVA+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NY
Sbjct 6933 YLCGFIKQKLALGGSVAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGVNY 6992
Query 7010 LGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMI 7069
LGK REQIDGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI
Sbjct 6993 LGKLREQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMI 7052
Query 7070 LSLLSKGRLIIRENNRVVISSDVLVNN 7096
SLL GRLIIRENNRVV+SSD+LVNN
Sbjct 7053 YSLLENGRLIIRENNRVVVSSDILVNN 7079
>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067
Score = 12908 bits (33499), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 6092/7102 (86%), Positives = 6576/7102 (93%), Gaps = 41/7102 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA + HGH +VELVAEL+GIQ+GRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAELDGIQFGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHS+G DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
TRYVDNNFCGPDGYPLECIKD LARAGK+ CTLSEQLD+I++KRGVYCCREHEHEI W
Sbjct 181 VVTRYVDNNFCGPDGYPLECIKDFLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERSEKSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSEKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + EVGPEHS+A+YHN S ++T LRKGGRT FGGCVFSYVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFSYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIG NHTG+ GE E LN++LLEIL +E+VNINIVGDF+ NEE+AIILASF
Sbjct 421 AYWVPRASANIGANHTGITGENVETLNEDLLEILNRERVNINIVGDFRFNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SAS SAF+ETVKGLDYK+FK IVESCGN+KVT GK GAWNIG+Q+SIL+PL F S+A
Sbjct 481 SASPSAFIETVKGLDYKSFKVIVESCGNYKVTNGKPVTGAWNIGQQRSILTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIFSRTL+ A +S+ LQ+AA+T LDGIS+ SLRL+DAM++TSDL TN++VVMAY
Sbjct 541 AGVIRSIFSRTLDAANHSILDLQRAAVTTLDGISEQSLRLVDAMVYTSDLLTNSVVVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ T QWL+N+ GT +KLKPV W+E K GVEFLRD WEI+KF+ T +++
Sbjct 601 VTGGLVQQTMQWLSNMLGTAVDKLKPVFTWVEAKLSAGVEFLRDAWEILKFLITGVFDVI 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI IKE V+ F +VNK L +C D + I G KL+ALNLGE F+ S+GLYR+C
Sbjct 661 KGQIQVATDNIKECVKIFLGVVNKALEMCLDQVTIAGTKLRALNLGEVFIAQSRGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG+ T + +EEVVLK+G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDAHDTVLTSEEVVLKSGELEALETPIDSFTSGAVVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVCINGLMLLE+++ E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCINGLMLLELENKEQYCALSPGLLATNNVFRLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELD R+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLTP+GIDLDE
Sbjct 841 KITFELDVRVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTPMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKP 959
WS+AT+YLFD++GE KL+S MYCSFYPPDE+E+ E E+ E + ++EYGTEDDY+G P
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCE--ECEDEEETCEHEYGTEDDYKGLP 958
Query 960 LEFGATSAALQ-PEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
LEFGA++ EEE+EEDWLDD + +
Sbjct 959 LEFGASTETPHVEEEEEEEDWLDDAIEAEPEPE--------------------------- 991
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
+ VN F GYLKLTDNV IK DIV+EA+ KPTV+VNAAN +LKHGGGVAGALNKA
Sbjct 992 PLPEEPVNQFVGYLKLTDNVAIKCIDIVKEAQSAKPTVIVNAANTHLKHGGGVAGALNKA 1051
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
TN AMQ ESD+YI NGPL VGGSC+LSGHNLA+ CLHVVGPN+N GED+QLLK AYENF
Sbjct 1052 TNGAMQNESDEYIRQNGPLTVGGSCLLSGHNLAEKCLHVVGPNLNAGEDVQLLKRAYENF 1111
Query 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
N +VLLAPLLSAGIFGA P+ SL++CV+ VRT VYLAV DK+LYD++V +L+ K
Sbjct 1112 NSQDVLLAPLLSAGIFGAKPLQSLKMCVEIVRTQVYLAVNDKSLYDQIVLDYLDSLKPK- 1170
Query 1199 VEQKIAEIPKEEVKPFITES---KPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL 1255
E P +E +P + E +P E+ KIKAC++EVTTTLEETKFLT LLL
Sbjct 1171 -----VESPNKEEEPKLEEPKAVQPVAEKPVDVKPKIKACIDEVTTTLEETKFLTNKLLL 1225
Query 1256 YIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAK 1315
+ DING L+ DS ++ D++FL+KDAPYIVGDV+ G +T V+IP KK+GGTTEMLA+
Sbjct 1226 FADINGKLYQDSQNMLRGEDMSFLEKDAPYIVGDVITSGDITCVIIPAKKSGGTTEMLAR 1285
Query 1316 ALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNL 1375
AL++VP YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS NEK+E+LGTVSWNL
Sbjct 1286 ALKEVPVAEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSETPNEKEEVLGTVSWNL 1345
Query 1376 REMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLI 1435
REMLAHAEETRKLMP+C++ +AI++TIQRKYKGIK+QEG+VDYG RF+FYTSK VAS+I
Sbjct 1346 REMLAHAEETRKLMPICLDVRAIMATIQRKYKGIKVQEGIVDYGVRFFFYTSKEPVASII 1405
Query 1436 NTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSK 1495
LN LNE LVTMP+GYVTHGLNLEEAAR MRSLK PA VSVSSPDAVTAYNGYLTSSSK
Sbjct 1406 TKLNSLNEPLVTMPIGYVTHGLNLEEAARCMRSLKAPAVVSVSSPDAVTAYNGYLTSSSK 1465
Query 1496 TPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTS-NPTTFHLDGEVITFD 1554
TPEE+F+ET SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T+ +P FHLDGEV+ D
Sbjct 1466 TPEEYFVETTSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTTGSPIEFHLDGEVLPLD 1525
Query 1555 NLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHE 1614
LK+LLSLREV+TIKVFTTVDN NLHT +VDMSMTYGQQFGPTYLDGADVTKIKPH +HE
Sbjct 1526 KLKSLLSLREVKTIKVFTTVDNTNLHTHIVDMSMTYGQQFGPTYLDGADVTKIKPHVNHE 1585
Query 1615 GKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNC 1674
GKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNNC
Sbjct 1586 GKTFFVLPSDDTLRSEAFEYYHTIDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNC 1645
Query 1675 YLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSY 1734
YL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM++
Sbjct 1646 YLSSVLLALQQVEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTH 1705
Query 1735 LFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQAT 1794
L QHANL+S KRVLNVVCK CGQ+ TTLKGVEAVMYMGTLSY++ K GV IPC CG+ AT
Sbjct 1706 LLQHANLESAKRVLNVVCKHCGQKTTTLKGVEAVMYMGTLSYDELKTGVSIPCVCGRNAT 1765
Query 1795 KYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLT 1854
+YLVQQES FVMMSAPPA+Y+L+ G F CA+EYTGNYQCGHY HIT+KETLY +DGA LT
Sbjct 1766 QYLVQQESSFVMMSAPPAEYKLQQGAFLCANEYTGNYQCGHYTHITAKETLYRVDGAHLT 1825
Query 1855 KSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL 1914
K SEYKGP+TDVFYKE SYTT IKPV+YKLDGV TEI+PKLD YYKK N+Y+TEQPIDL
Sbjct 1826 KMSEYKGPVTDVFYKETSYTTAIKPVSYKLDGVTYTEIEPKLDGYYKKGNAYYTEQPIDL 1885
Query 1915 VPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKH 1974
VP QP PNASFDNFK C N KFADDLNQ+TG+KKPASREL VTFFPDLNGDVVAIDY+H
Sbjct 1886 VPTQPMPNASFDNFKLTCSNTKFADDLNQMTGFKKPASRELTVTFFPDLNGDVVAIDYRH 1945
Query 1975 YTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQ 2034
Y+ SFKKGAKL+HKPI+WH+N TNK TYKPN WC+RCLWSTKPV+TSNSF+VL ED Q
Sbjct 1946 YSTSFKKGAKLVHKPILWHINQTTNKTTYKPNIWCLRCLWSTKPVDTSNSFEVLVVEDTQ 2005
Query 2035 GMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTD 2094
GMDNLACE SEEVVENPT+QK+++EC+VKTTEVVG++ILKP+ +K+T+E+GH D
Sbjct 2006 GMDNLACESQTTTSEEVVENPTVQKEIIECDVKTTEVVGNVILKPSEEGVKVTQELGHED 2065
Query 2095 LMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT 2154
LMAAYV+ +S+TIKKPNELS LGLKTLATHG AA+NSVPW I Y KPFL + T+
Sbjct 2066 LMAAYVEETSITIKKPNELSLALGLKTLATHGAAAINSVPWSKILAYVKPFLGQTAVITS 2125
Query 2155 NIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEAS 2214
N + +C+ RV +NYMPY TLL QLCTFT+STNSRIKAS+PTTIAKN+VKSV K CL+
Sbjct 2126 NCIKKCVQRVFSNYMPYVITLLFQLCTFTKSTNSRIKASLPTTIAKNSVKSVAKLCLDVC 2185
Query 2215 FNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNST 2274
NY+KSP FSKL I++W LLLS+CLGSL Y TA LGV +S+LG+PSYC G RE Y+NS+
Sbjct 2186 INYVKSPKFSKLFTIVMWLLLLSICLGSLTYVTAVLGVCLSSLGVPSYCDGVRELYINSS 2245
Query 2275 NVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILF 2334
NVT +C G PCSVCLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+LF
Sbjct 2246 NVTTMDFCQGYFPCSVCLSGLDSLDSYPALETIQVTISSYKLDLTFLGLAAEWLLAYMLF 2305
Query 2335 TRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVW 2394
T+FFY+LGL+AIMQ FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYYVW
Sbjct 2306 TKFFYLLGLSAIMQAFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYVW 2365
Query 2395 KSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVN 2454
KSYVH++DGC SSTCMMCYKRNRATRVECTTIVNGV+RSFYVYANGG+GFCK HNWNC+N
Sbjct 2366 KSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGVKRSFYVYANGGRGFCKAHNWNCLN 2425
Query 2455 CDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYE 2514
CDTFCAGSTFISDEVARDLSLQFKRPINPTDQS+Y+VDSVTVKNG++HLYFDKAGQKTYE
Sbjct 2426 CDTFCAGSTFISDEVARDLSLQFKRPINPTDQSAYVVDSVTVKNGALHLYFDKAGQKTYE 2485
Query 2515 RHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQ 2574
RH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES+AKSASVYYSQLMCQPILLLDQ
Sbjct 2486 RHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESAAKSASVYYSQLMCQPILLLDQ 2545
Query 2575 ALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFI 2634
ALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF+
Sbjct 2546 ALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFV 2605
Query 2635 SAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDC 2694
SAARQG VD+DV+TKDV+ECLKLSH SDIEVTGDSCNN+MLTYNKVENMTPRDLGACIDC
Sbjct 2606 SAARQGVVDTDVDTKDVIECLKLSHHSDIEVTGDSCNNFMLTYNKVENMTPRDLGACIDC 2665
Query 2695 SARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVV 2754
+ARHINAQVAKSHN++L+WNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV+
Sbjct 2666 NARHINAQVAKSHNVSLVWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVI 2725
Query 2755 TTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDG 2814
TTKI+LKGGK+V+ W K L+KVTL+ + A Y+I PVH +S H +++EIIGYKAI
Sbjct 2726 TTKISLKGGKVVSTWFKLLLKVTLLCVLAALFCYVIMPVHSLSVHDGYTNEIIGYKAIQD 2785
Query 2815 GVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTIL 2874
GVTRDI STD CFANKHA FD+WFSQRGGSY NDK CP++AA+ITRE+GF+VPGLPGT+L
Sbjct 2786 GVTRDIVSTDDCFANKHAGFDSWFSQRGGSYRNDKNCPVVAAIITREIGFIVPGLPGTVL 2845
Query 2875 RTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCY 2934
R NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYCY
Sbjct 2846 RALNGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCY 2905
Query 2935 DTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEA 2994
DTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2906 DTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEV 2965
Query 2995 GVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVA 3054
GVC+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+A
Sbjct 2966 GVCLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIA 3025
Query 3055 IVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTF 3114
I+VTC AYYFM+FRRAFGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYS+ YLYLTF
Sbjct 3026 ILVTCAAYYFMKFRRAFGEYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFYLYLTF 3085
Query 3115 YLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFST 3174
Y TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KHF+WFFSNYLK+RV+FNGV+FST
Sbjct 3086 YFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHFHWFFSNYLKKRVMFNGVTFST 3145
Query 3175 FEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL 3234
FEEAALCTFLLNKEMYL+LRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCHL
Sbjct 3146 FEEAALCTFLLNKEMYLRLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHL 3205
Query 3235 AKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW 3294
AKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW
Sbjct 3206 AKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW 3265
Query 3295 LDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKV 3354
LDD VYCPRHV+CT+EDMLNPNY+DLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LKV
Sbjct 3266 LDDTVYCPRHVVCTAEDMLNPNYDDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKV 3325
Query 3355 DTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFN 3414
DT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGFN
Sbjct 3326 DTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFN 3385
Query 3415 IDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAA 3474
IDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAA
Sbjct 3386 IDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAA 3445
Query 3475 VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKEL 3534
VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKEL
Sbjct 3446 VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKEL 3505
Query 3535 LQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVL 3594
LQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+L
Sbjct 3506 LQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLIL 3565
Query 3595 VQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVY 3654
VQSTQWSLFFF+YENAFLPFA+GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMVY
Sbjct 3566 VQSTQWSLFFFVYENAFLPFALGIMAVAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVY 3625
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNV 3714
MPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMNV
Sbjct 3626 MPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNV 3685
Query 3715 LTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGN 3774
+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITGN
Sbjct 3686 ITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGN 3745
Query 3775 TLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNS 3834
TLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+S
Sbjct 3746 TLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSS 3805
Query 3835 IDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQL 3894
IDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQL
Sbjct 3806 IDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQL 3865
Query 3895 HNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSY 3954
HNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSY
Sbjct 3866 HNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSY 3925
Query 3955 AAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYK 4014
AA+ATAQEAYEQAV+NGDSEVVLKKLKKSLNVAKSEFD DAAMQRKLEKMADQAMTQMYK
Sbjct 3926 AAYATAQEAYEQAVSNGDSEVVLKKLKKSLNVAKSEFDHDAAMQRKLEKMADQAMTQMYK 3985
Query 4015 QARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVI 4074
QARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV+
Sbjct 3986 QARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVV 4045
Query 4075 PDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN 4134
PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRAN
Sbjct 4046 PDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN 4105
Query 4135 SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN KGGRFVLALLSD QDLKWA
Sbjct 4106 SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNAKGGRFVLALLSDHQDLKWA 4165
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA
Sbjct 4166 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4225
Query 4255 GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA 4314
GNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA
Sbjct 4226 GNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA 4285
Query 4315 NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCG 4374
NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVCG
Sbjct 4286 NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCG 4345
Query 4375 MWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKV 4434
MWKGYGCSCDQLREPM+QSADA +FLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYN+KV
Sbjct 4346 MWKGYGCSCDQLREPMMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEKV 4405
Query 4435 AGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFF 4494
AGFAKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+K+CPAVA HDFF
Sbjct 4406 AGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLIKECPAVAVHDFF 4465
Query 4495 KFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDW 4554
KFR+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDD+YFNKKDW
Sbjct 4466 KFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDNYFNKKDW 4525
Query 4555 YDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDF 4614
YDFVENPD+LRVYANLGERVR+ALLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWYDFGDF
Sbjct 4526 YDFVENPDVLRVYANLGERVRRALLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDF 4585
Query 4615 IQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKL 4674
+Q PG GVP+VDSYYSLLMPILTLT+AL AESH+D DL KP +KWDLLKYDFTEERL L
Sbjct 4586 VQVAPGCGVPIVDSYYSLLMPILTLTKALAAESHMDADLAKPLVKWDLLKYDFTEERLCL 4645
Query 4675 FDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVV 4734
FDRYFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVV
Sbjct 4646 FDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVV 4705
Query 4735 STGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALT 4794
STGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALT
Sbjct 4706 STGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALT 4765
Query 4795 NNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPT 4854
NNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPT
Sbjct 4766 NNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPT 4825
Query 4855 MCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYE 4914
MCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYE
Sbjct 4826 MCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYE 4885
Query 4915 DQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAAT 4974
DQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAAT
Sbjct 4886 DQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAAT 4945
Query 4975 RGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKH 5034
RGATVVIGTSKFYGGWHNMLKTVYSDVE+PHLMGWDYPKCDRAMPNMLRIMASL+LARKH
Sbjct 4946 RGATVVIGTSKFYGGWHNMLKTVYSDVESPHLMGWDYPKCDRAMPNMLRIMASLILARKH 5005
Query 5035 TTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5094
+TCC+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTA
Sbjct 5006 STCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5065
Query 5095 NVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDA 5154
NVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV+EFYAYLRKHFSMMILSDDA
Sbjct 5066 NVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDA 5125
Query 5155 VVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQ 5214
VVC+NS YA+QGLVASIKNFK+VLYYQNNVFMSEAKCWTETDLT+GPHEFCSQHTMLVKQ
Sbjct 5126 VVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTRGPHEFCSQHTMLVKQ 5185
Query 5215 GDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFH 5274
GDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFH
Sbjct 5186 GDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFH 5245
Query 5275 LYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNS 5334
LYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNS
Sbjct 5246 LYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNS 5305
Query 5335 QTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSY 5394
QTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSY
Sbjct 5306 QTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSY 5365
Query 5395 YCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERL 5454
YCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERL
Sbjct 5366 YCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERL 5425
Query 5455 KLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKN 5514
KLFAAETLKATEETFKLSYGIATVREVLSDREL+LSWEVGKPRPPLNRNYVFTGYRVTKN
Sbjct 5426 KLFAAETLKATEETFKLSYGIATVREVLSDRELYLSWEVGKPRPPLNRNYVFTGYRVTKN 5485
Query 5515 SKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRIT 5574
SKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRIT
Sbjct 5486 SKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRIT 5545
Query 5575 GLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACS 5634
GLYPTLNIS+EFSSNVANYQK+GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACS
Sbjct 5546 GLYPTLNISNEFSSNVANYQKIGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACS 5605
Query 5635 HAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADI 5694
HAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADI
Sbjct 5606 HAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADI 5665
Query 5695 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK 5754
VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK
Sbjct 5666 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK 5725
Query 5755 TIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINR 5814
TIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHK+KSAQCFKM+YKGVITHDVSSAINR
Sbjct 5726 TIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKEKSAQCFKMYYKGVITHDVSSAINR 5785
Query 5815 PQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTT 5874
PQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTT
Sbjct 5786 PQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTT 5845
Query 5875 ETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFK 5934
ETAHSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLE+PRRNVATLQAENVTGLFK
Sbjct 5846 ETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEVPRRNVATLQAENVTGLFK 5905
Query 5935 DCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGY 5994
DCSK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGY
Sbjct 5906 DCSKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGY 5965
Query 5995 PNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPN 6054
PNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAVPTGYVDT N
Sbjct 5966 PNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTEN 6025
Query 6055 NTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHG 6114
+T+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFVLWAHG
Sbjct 6026 STEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHG 6085
Query 6115 FELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGF 6174
FELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPFMIDVQQWGF
Sbjct 6086 FELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGF 6145
Query 6175 TGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAAC 6234
TGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDELKINAAC
Sbjct 6146 TGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELKINAAC 6205
Query 6235 RKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYS 6294
RKVQHMVVK+ALLADKF VLHDIGNPKAI+CVPQA+V+WKFYDAQPCSDKAYKIEELFYS
Sbjct 6206 RKVQHMVVKSALLADKFTVLHDIGNPKAIRCVPQAEVDWKFYDAQPCSDKAYKIEELFYS 6265
Query 6295 YATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTP 6354
YATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTP
Sbjct 6266 YATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTP 6325
Query 6355 AFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHAN 6414
AFDKSAF +LKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHAN
Sbjct 6326 AFDKSAFTHLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHAN 6385
Query 6415 EYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEV 6474
EYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFT+LQSLENVA+NVVNKGHFDGQ GE
Sbjct 6386 EYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTKLQSLENVAYNVVNKGHFDGQSGEA 6445
Query 6475 PVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAAN 6534
PVSIINN VYTKVDG+DVE+FENKTTLPVNVAFELWAKRNIKPVPE+KILNNLGVDIAAN
Sbjct 6446 PVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAAN 6505
Query 6535 TVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVL 6594
VIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ L V FDGRV+GQVD FRNARNGVL
Sbjct 6506 NVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLIVLFDGRVEGQVDFFRNARNGVL 6565
Query 6595 ITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQE 6654
ITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQSR+L++
Sbjct 6566 ITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLED 6625
Query 6655 FKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESP 6714
FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR ++S
Sbjct 6626 FKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSL 6685
Query 6715 FELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTI 6774
+LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTI
Sbjct 6686 LKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTI 6745
Query 6775 DYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATL 6834
DY EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG++A +
Sbjct 6746 DYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVI 6805
Query 6835 PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLV 6894
PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLV
Sbjct 6806 PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLV 6865
Query 6895 DSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGF 6954
DSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTK+V K+NDSKEGFFTY+CGF
Sbjct 6866 DSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKHVLKDNDSKEGFFTYLCGF 6925
Query 6955 IQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPR 7014
I+QKLALGGSVA+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NYLGKP+
Sbjct 6926 IKQKLALGGSVAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGVNYLGKPK 6985
Query 7015 EQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLS 7074
EQIDGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI SLL
Sbjct 6986 EQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLE 7045
Query 7075 KGRLIIRENNRVVISSDVLVNN 7096
KGRLIIRENNRVV+SSD+LVNN
Sbjct 7046 KGRLIIRENNRVVVSSDILVNN 7067
>sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 PE=1 SV=1
Length=4405
Score = 9137 bits (23709), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 4401/4401 (100%), Positives = 4401/4401 (100%), Gaps = 0/4401 (0%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV
Sbjct 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK
Sbjct 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW
Sbjct 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI
Sbjct 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL
Sbjct 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC
Sbjct 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF
Sbjct 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA
Sbjct 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY
Sbjct 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV
Sbjct 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC
Sbjct 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG
Sbjct 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN 840
TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN
Sbjct 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN 840
Query 841 ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW 900
ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW
Sbjct 841 ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW 900
Query 901 SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL 960
SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL
Sbjct 901 SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL 960
Query 961 EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV 1020
EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV
Sbjct 961 EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV 1020
Query 1021 QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN
Sbjct 1021 QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
Query 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ 1140
NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ
Sbjct 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ 1140
Query 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE 1200
HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE
Sbjct 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE 1200
Query 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN 1260
QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN
Sbjct 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN 1260
Query 1261 GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV 1320
GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV
Sbjct 1261 GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV 1320
Query 1321 PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA 1380
PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA
Sbjct 1321 PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA 1380
Query 1381 HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND 1440
HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND
Sbjct 1381 HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND 1440
Query 1441 LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH 1500
LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH
Sbjct 1441 LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH 1500
Query 1501 FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL 1560
FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL
Sbjct 1501 FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL 1560
Query 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV
Sbjct 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
Query 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL
Sbjct 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
Query 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN
Sbjct 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
Query 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ
Sbjct 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
Query 1801 ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK 1860
ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK
Sbjct 1801 ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK 1860
Query 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY 1920
GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY
Sbjct 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY 1920
Query 1921 PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK
Sbjct 1921 PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
Query 1981 KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA 2040
KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA
Sbjct 1981 KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA 2040
Query 2041 CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV
Sbjct 2041 CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
Query 2101 DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC 2160
DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC
Sbjct 2101 DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC 2160
Query 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS
Sbjct 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
Query 2221 PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT 2280
PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT
Sbjct 2221 PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT 2280
Query 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV
Sbjct 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
Query 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV
Sbjct 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA
Sbjct 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH
Sbjct 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV
Sbjct 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG
Sbjct 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
Query 2641 FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN 2700
FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN
Sbjct 2641 FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN 2700
Query 2701 AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL 2760
AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL
Sbjct 2701 AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL 2760
Query 2761 KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI 2820
KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI
Sbjct 2761 KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI 2820
Query 2821 ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD 2880
ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD
Sbjct 2821 ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD 2880
Query 2881 FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE 2940
FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE
Sbjct 2881 FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE 2940
Query 2941 GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST 3000
GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST
Sbjct 2941 GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST 3000
Query 3001 SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL
Sbjct 3001 SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
Query 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV
Sbjct 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
Query 3121 SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL 3180
SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL
Sbjct 3121 SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL 3180
Query 3181 CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND 3240
CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND
Sbjct 3181 CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND 3240
Query 3241 FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY 3300
FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY
Sbjct 3241 FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY 3300
Query 3301 CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK 3360
CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK
Sbjct 3301 CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK 3360
Query 3361 TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV 3420
TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV
Sbjct 3361 TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV 3420
Query 3421 SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR 3480
SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR
Sbjct 3421 SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR 3480
Query 3481 WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN
Sbjct 3481 WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
Query 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW
Sbjct 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
Query 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV
Sbjct 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
Query 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK
Sbjct 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
Query 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM
Sbjct 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
Query 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL
Sbjct 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
Query 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL
Sbjct 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
Query 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA
Sbjct 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
Query 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED
Sbjct 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
Query 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY
Sbjct 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
Query 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ 4140
KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ
Sbjct 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ 4140
Query 4141 NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD 4200
NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD
Sbjct 4141 NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD 4200
Query 4201 GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV 4260
GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV
Sbjct 4201 GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV 4260
Query 4261 PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES 4320
PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES
Sbjct 4261 PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES 4320
Query 4321 FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG 4380
FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG
Sbjct 4321 FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG 4380
Query 4381 CSCDQLREPMLQSADAQSFLN 4401
CSCDQLREPMLQSADAQSFLN
Sbjct 4381 CSCDQLREPMLQSADAQSFLN 4401
>sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respiratory
syndrome coronavirus OX=694009 GN=1a PE=1 SV=1
Length=4382
Score = 7474 bits (19391), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3540/4408 (80%), Positives = 3938/4408 (89%), Gaps = 37/4408 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA + HGH +VELVAE++GIQYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGK+ CTLSEQLD+I++KRGVYCCR+HEHEIAW
Sbjct 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVASP ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + E+GPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+Q+S+L+PL F S+A
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIF+RTL+ A +S+ LQ+AA+TILDGIS+ SLRL+DAM++TSDL TN++++MAY
Sbjct 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ TSQWL+N+ GT EKL+P+ +W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVC+NGLMLLEIKD E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV EVQGYK+V
Sbjct 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ-YEYGTEDDYQGK 958
WS+AT+YLFD++GE +S MYCSFYPPDE+EE+ EEE T +EYGTEDDYQG
Sbjct 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
Query 959 PLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
PLEFGA++ ++ EEE+EEDWLDD ++Q+ E+
Sbjct 961 PLEFGASAETVRVEEEEEEDWLDDTTEQS-------------------EI-----EPEPE 996
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
VN F+GYLKLTDNV IK DIV+EA+ P V+VNAAN++LKHGGGVAGALNKA
Sbjct 997 PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKA 1056
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
TN AMQ ESDDYI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYENF
Sbjct 1057 TNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENF 1116
Query 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
N ++LLAPLLSAGIFGA P+ SL+VCV TVRT VY+AV DK LY+++V +L+ +
Sbjct 1117 NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPR- 1175
Query 1199 VEQKIAEIPKEEVKPFITESK---PSVEQRKQDDK-KIKACVEEVTTTLEETKFLTENLL 1254
E PK+E P +SK SV Q+ D K KIKAC++EVTTTLEETKFLT LL
Sbjct 1176 -----VEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLL 1230
Query 1255 LYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLA 1314
L+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML+
Sbjct 1231 LFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLS 1290
Query 1315 KALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWN 1374
+AL+KVP D YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSWN
Sbjct 1291 RALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWN 1350
Query 1375 LREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASL 1434
LREMLAHAEETRKLMP+C++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS+
Sbjct 1351 LREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASI 1410
Query 1435 INTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS 1494
I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSSS
Sbjct 1411 ITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSS 1470
Query 1495 KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVITF 1553
KT EEHF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGEV++
Sbjct 1471 KTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSL 1530
Query 1554 DNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSH 1613
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH +H
Sbjct 1531 DKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNH 1590
Query 1614 EGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNN 1673
EGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNN
Sbjct 1591 EGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN 1650
Query 1674 CYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMS 1733
CYL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM+
Sbjct 1651 CYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMT 1710
Query 1734 YLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQA 1793
+L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+ A
Sbjct 1711 HLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDA 1770
Query 1794 TKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALL 1853
T+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA L
Sbjct 1771 TQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHL 1830
Query 1854 TKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPID 1913
TK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPID
Sbjct 1831 TKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPID 1890
Query 1914 LVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYK 1973
LVP QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY+
Sbjct 1891 LVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYR 1950
Query 1974 HYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDA 2033
HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1951 HYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDT 2010
Query 2034 QGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHT 2093
QGMDNLACE +P SEEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+GH
Sbjct 2011 QGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHE 2070
Query 2094 DLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTT 2153
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + TT
Sbjct 2071 DLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITT 2130
Query 2154 TNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEA 2213
+N R RV NYMPY FTLL QLCTFT+STNSRI+AS+PTTIAKN+VKSV K CL+A
Sbjct 2131 SNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
Query 2214 SFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNS 2273
NY+KSP FSKL I +W LLLS+CLGSLI TAA GVL+SN G PSYC G RE YLNS
Sbjct 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNS 2250
Query 2274 TNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYIL 2333
+NVT +C GS PCS+CLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+L
Sbjct 2251 SNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYML 2310
Query 2334 FTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYV 2393
FT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY+
Sbjct 2311 FTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYI 2370
Query 2394 WKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCV 2453
WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC+
Sbjct 2371 WKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCL 2430
Query 2454 NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTY 2513
NCDTFC GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV VKNG++HLYFDKAGQKTY
Sbjct 2431 NCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTY 2490
Query 2514 ERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLD 2573
ERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES++KSASVYYSQLMCQPILLLD
Sbjct 2491 ERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLD 2550
Query 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
QALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF
Sbjct 2551 QALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTF 2610
Query 2634 ISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACID 2693
+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACID
Sbjct 2611 VSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACID 2670
Query 2694 CSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNV 2753
C+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV
Sbjct 2671 CNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNV 2730
Query 2754 VTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAID 2813
+TTKI+LKGGKIV+ K ++K TL+ + A + Y++ PVH +S H +++EIIGYKAI
Sbjct 2731 ITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQ 2790
Query 2814 GGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTI 2873
GVTRDI STD CFANKHA FD WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT+
Sbjct 2791 DGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTV 2850
Query 2874 LRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC 2933
LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYC
Sbjct 2851 LRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYC 2910
Query 2934 YDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
YDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2911 YDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE 2970
Query 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
G+C+STSGRWVLNN++YR+L GVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+
Sbjct 2971 VGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGII 3030
Query 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
AI+VTC AYYFM+FRR FGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYSV YLYLT
Sbjct 3031 AILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLT 3090
Query 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFS 3173
FY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNGV+FS
Sbjct 3091 FYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFS 3150
Query 3174 TFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCH 3233
TFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCH
Sbjct 3151 TFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCH 3210
Query 3234 LAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
LAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL
Sbjct 3211 LAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3270
Query 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
WLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LK
Sbjct 3271 WLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLK 3330
Query 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
VDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGF
Sbjct 3331 VDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGF 3390
Query 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
NIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYA
Sbjct 3391 NIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYA 3450
Query 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKE
Sbjct 3451 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
Query 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
LLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+
Sbjct 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLI 3570
Query 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMV
Sbjct 3571 LVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMV 3630
Query 3654 YMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMN 3713
YMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMN
Sbjct 3631 YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMN 3690
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITG
Sbjct 3691 VITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
NTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+
Sbjct 3751 NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKS 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ
Sbjct 3811 SIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPS 3953
LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPS
Sbjct 3871 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPS 3930
Query 3954 YAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 4013
YAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY
Sbjct 3931 YAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 3990
Query 4014 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4073
KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV
Sbjct 3991 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4050
Query 4074 IPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 4133
+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRA
Sbjct 4051 VPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRA 4110
Query 4134 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKW 4193
NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLKW
Sbjct 4111 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKW 4170
Query 4194 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4253
ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ
Sbjct 4171 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4230
Query 4254 AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
AGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE
Sbjct 4231 AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4290
Query 4314 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVC 4373
ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVC
Sbjct 4291 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 4350
Query 4374 GMWKGYGCSCDQLREPMLQSADAQSFLN 4401
GMWKGYGCSCDQLREP++QSADA +FLN
Sbjct 4351 GMWKGYGCSCDQLREPLMQSADASTFLN 4378
>sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus
HKU3 OX=442736 GN=1a PE=3 SV=1
Length=4376
Score = 7447 bits (19321), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3532/4407 (80%), Positives = 3926/4407 (89%), Gaps = 41/4407 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA + HGH +VELVAEL+GIQ+GRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAELDGIQFGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHS+G DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
TRYVDNNFCGPDGYPLECIKD LARAGK+ CTLSEQLD+I++KRGVYCCREHEHEI W
Sbjct 181 VVTRYVDNNFCGPDGYPLECIKDFLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERSEKSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSEKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + EVGPEHS+A+YHN S ++T LRKGGRT FGGCVFSYVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFSYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIG NHTG+ GE E LN++LLEIL +E+VNINIVGDF+ NEE+AIILASF
Sbjct 421 AYWVPRASANIGANHTGITGENVETLNEDLLEILNRERVNINIVGDFRFNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SAS SAF+ETVKGLDYK+FK IVESCGN+KVT GK GAWNIG+Q+SIL+PL F S+A
Sbjct 481 SASPSAFIETVKGLDYKSFKVIVESCGNYKVTNGKPVTGAWNIGQQRSILTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIFSRTL+ A +S+ LQ+AA+T LDGIS+ SLRL+DAM++TSDL TN++VVMAY
Sbjct 541 AGVIRSIFSRTLDAANHSILDLQRAAVTTLDGISEQSLRLVDAMVYTSDLLTNSVVVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ T QWL+N+ GT +KLKPV W+E K GVEFLRD WEI+KF+ T +++
Sbjct 601 VTGGLVQQTMQWLSNMLGTAVDKLKPVFTWVEAKLSAGVEFLRDAWEILKFLITGVFDVI 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI IKE V+ F +VNK L +C D + I G KL+ALNLGE F+ S+GLYR+C
Sbjct 661 KGQIQVATDNIKECVKIFLGVVNKALEMCLDQVTIAGTKLRALNLGEVFIAQSRGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG+ T + +EEVVLK+G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDAHDTVLTSEEVVLKSGELEALETPIDSFTSGAVVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVCINGLMLLE+++ E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCINGLMLLELENKEQYCALSPGLLATNNVFRLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELD R+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLTP+GIDLDE
Sbjct 841 KITFELDVRVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTPMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKP 959
WS+AT+YLFD++GE KL+S MYCSFYPPDE+E+ E E+ E + ++EYGTEDDY+G P
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCE--ECEDEEETCEHEYGTEDDYKGLP 958
Query 960 LEFGATSAALQ-PEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
LEFGA++ EEE+EEDWLDD + +
Sbjct 959 LEFGASTETPHVEEEEEEEDWLDDAIEAEPEPE--------------------------- 991
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
+ VN F GYLKLTDNV IK DIV+EA+ KPTV+VNAAN +LKHGGGVAGALNKA
Sbjct 992 PLPEEPVNQFVGYLKLTDNVAIKCIDIVKEAQSAKPTVIVNAANTHLKHGGGVAGALNKA 1051
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
TN AMQ ESD+YI NGPL VGGSC+LSGHNLA+ CLHVVGPN+N GED+QLLK AYENF
Sbjct 1052 TNGAMQNESDEYIRQNGPLTVGGSCLLSGHNLAEKCLHVVGPNLNAGEDVQLLKRAYENF 1111
Query 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
N +VLLAPLLSAGIFGA P+ SL++CV+ VRT VYLAV DK+LYD++V +L+ K
Sbjct 1112 NSQDVLLAPLLSAGIFGAKPLQSLKMCVEIVRTQVYLAVNDKSLYDQIVLDYLDSLKPK- 1170
Query 1199 VEQKIAEIPKEEVKPFITES---KPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL 1255
E P +E +P + E +P E+ KIKAC++EVTTTLEETKFLT LLL
Sbjct 1171 -----VESPNKEEEPKLEEPKAVQPVAEKPVDVKPKIKACIDEVTTTLEETKFLTNKLLL 1225
Query 1256 YIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAK 1315
+ DING L+ DS ++ D++FL+KDAPYIVGDV+ G +T V+IP KK+GGTTEMLA+
Sbjct 1226 FADINGKLYQDSQNMLRGEDMSFLEKDAPYIVGDVITSGDITCVIIPAKKSGGTTEMLAR 1285
Query 1316 ALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNL 1375
AL++VP YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS NEK+E+LGTVSWNL
Sbjct 1286 ALKEVPVAEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSETPNEKEEVLGTVSWNL 1345
Query 1376 REMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLI 1435
REMLAHAEETRKLMP+C++ +AI++TIQRKYKGIK+QEG+VDYG RF+FYTSK VAS+I
Sbjct 1346 REMLAHAEETRKLMPICLDVRAIMATIQRKYKGIKVQEGIVDYGVRFFFYTSKEPVASII 1405
Query 1436 NTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSK 1495
LN LNE LVTMP+GYVTHGLNLEEAAR MRSLK PA VSVSSPDAVTAYNGYLTSSSK
Sbjct 1406 TKLNSLNEPLVTMPIGYVTHGLNLEEAARCMRSLKAPAVVSVSSPDAVTAYNGYLTSSSK 1465
Query 1496 TPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTS-NPTTFHLDGEVITFD 1554
TPEE+F+ET SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T+ +P FHLDGEV+ D
Sbjct 1466 TPEEYFVETTSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTTGSPIEFHLDGEVLPLD 1525
Query 1555 NLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHE 1614
LK+LLSLREV+TIKVFTTVDN NLHT +VDMSMTYGQQFGPTYLDGADVTKIKPH +HE
Sbjct 1526 KLKSLLSLREVKTIKVFTTVDNTNLHTHIVDMSMTYGQQFGPTYLDGADVTKIKPHVNHE 1585
Query 1615 GKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNC 1674
GKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNNC
Sbjct 1586 GKTFFVLPSDDTLRSEAFEYYHTIDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNC 1645
Query 1675 YLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSY 1734
YL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM++
Sbjct 1646 YLSSVLLALQQVEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTH 1705
Query 1735 LFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQAT 1794
L QHANL+S KRVLNVVCK CGQ+ TTLKGVEAVMYMGTLSY++ K GV IPC CG+ AT
Sbjct 1706 LLQHANLESAKRVLNVVCKHCGQKTTTLKGVEAVMYMGTLSYDELKTGVSIPCVCGRNAT 1765
Query 1795 KYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLT 1854
+YLVQQES FVMMSAPPA+Y+L+ G F CA+EYTGNYQCGHY HIT+KETLY +DGA LT
Sbjct 1766 QYLVQQESSFVMMSAPPAEYKLQQGAFLCANEYTGNYQCGHYTHITAKETLYRVDGAHLT 1825
Query 1855 KSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL 1914
K SEYKGP+TDVFYKE SYTT IKPV+YKLDGV TEI+PKLD YYKK N+Y+TEQPIDL
Sbjct 1826 KMSEYKGPVTDVFYKETSYTTAIKPVSYKLDGVTYTEIEPKLDGYYKKGNAYYTEQPIDL 1885
Query 1915 VPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKH 1974
VP QP PNASFDNFK C N KFADDLNQ+TG+KKPASREL VTFFPDLNGDVVAIDY+H
Sbjct 1886 VPTQPMPNASFDNFKLTCSNTKFADDLNQMTGFKKPASRELTVTFFPDLNGDVVAIDYRH 1945
Query 1975 YTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQ 2034
Y+ SFKKGAKL+HKPI+WH+N TNK TYKPN WC+RCLWSTKPV+TSNSF+VL ED Q
Sbjct 1946 YSTSFKKGAKLVHKPILWHINQTTNKTTYKPNIWCLRCLWSTKPVDTSNSFEVLVVEDTQ 2005
Query 2035 GMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTD 2094
GMDNLACE SEEVVENPT+QK+++EC+VKTTEVVG++ILKP+ +K+T+E+GH D
Sbjct 2006 GMDNLACESQTTTSEEVVENPTVQKEIIECDVKTTEVVGNVILKPSEEGVKVTQELGHED 2065
Query 2095 LMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT 2154
LMAAYV+ +S+TIKKPNELS LGLKTLATHG AA+NSVPW I Y KPFL + T+
Sbjct 2066 LMAAYVEETSITIKKPNELSLALGLKTLATHGAAAINSVPWSKILAYVKPFLGQTAVITS 2125
Query 2155 NIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEAS 2214
N + +C+ RV +NYMPY TLL QLCTFT+STNSRIKAS+PTTIAKN+VKSV K CL+
Sbjct 2126 NCIKKCVQRVFSNYMPYVITLLFQLCTFTKSTNSRIKASLPTTIAKNSVKSVAKLCLDVC 2185
Query 2215 FNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNST 2274
NY+KSP FSKL I++W LLLS+CLGSL Y TA LGV +S+LG+PSYC G RE Y+NS+
Sbjct 2186 INYVKSPKFSKLFTIVMWLLLLSICLGSLTYVTAVLGVCLSSLGVPSYCDGVRELYINSS 2245
Query 2275 NVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILF 2334
NVT +C G PCSVCLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+LF
Sbjct 2246 NVTTMDFCQGYFPCSVCLSGLDSLDSYPALETIQVTISSYKLDLTFLGLAAEWLLAYMLF 2305
Query 2335 TRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVW 2394
T+FFY+LGL+AIMQ FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYYVW
Sbjct 2306 TKFFYLLGLSAIMQAFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYVW 2365
Query 2395 KSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVN 2454
KSYVH++DGC SSTCMMCYKRNRATRVECTTIVNGV+RSFYVYANGG+GFCK HNWNC+N
Sbjct 2366 KSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGVKRSFYVYANGGRGFCKAHNWNCLN 2425
Query 2455 CDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYE 2514
CDTFCAGSTFISDEVARDLSLQFKRPINPTDQS+Y+VDSVTVKNG++HLYFDKAGQKTYE
Sbjct 2426 CDTFCAGSTFISDEVARDLSLQFKRPINPTDQSAYVVDSVTVKNGALHLYFDKAGQKTYE 2485
Query 2515 RHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQ 2574
RH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES+AKSASVYYSQLMCQPILLLDQ
Sbjct 2486 RHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESAAKSASVYYSQLMCQPILLLDQ 2545
Query 2575 ALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFI 2634
ALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF+
Sbjct 2546 ALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFV 2605
Query 2635 SAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDC 2694
SAARQG VD+DV+TKDV+ECLKLSH SDIEVTGDSCNN+MLTYNKVENMTPRDLGACIDC
Sbjct 2606 SAARQGVVDTDVDTKDVIECLKLSHHSDIEVTGDSCNNFMLTYNKVENMTPRDLGACIDC 2665
Query 2695 SARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVV 2754
+ARHINAQVAKSHN++L+WNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV+
Sbjct 2666 NARHINAQVAKSHNVSLVWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVI 2725
Query 2755 TTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDG 2814
TTKI+LKGGK+V+ W K L+KVTL+ + A Y+I PVH +S H +++EIIGYKAI
Sbjct 2726 TTKISLKGGKVVSTWFKLLLKVTLLCVLAALFCYVIMPVHSLSVHDGYTNEIIGYKAIQD 2785
Query 2815 GVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTIL 2874
GVTRDI STD CFANKHA FD+WFSQRGGSY NDK CP++AA+ITRE+GF+VPGLPGT+L
Sbjct 2786 GVTRDIVSTDDCFANKHAGFDSWFSQRGGSYRNDKNCPVVAAIITREIGFIVPGLPGTVL 2845
Query 2875 RTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCY 2934
R NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYCY
Sbjct 2846 RALNGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCY 2905
Query 2935 DTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEA 2994
DTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2906 DTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEV 2965
Query 2995 GVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVA 3054
GVC+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+A
Sbjct 2966 GVCLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIA 3025
Query 3055 IVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTF 3114
I+VTC AYYFM+FRRAFGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYS+ YLYLTF
Sbjct 3026 ILVTCAAYYFMKFRRAFGEYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFYLYLTF 3085
Query 3115 YLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFST 3174
Y TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KHF+WFFSNYLK+RV+FNGV+FST
Sbjct 3086 YFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHFHWFFSNYLKKRVMFNGVTFST 3145
Query 3175 FEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL 3234
FEEAALCTFLLNKEMYL+LRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCHL
Sbjct 3146 FEEAALCTFLLNKEMYLRLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHL 3205
Query 3235 AKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW 3294
AKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW
Sbjct 3206 AKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW 3265
Query 3295 LDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKV 3354
LDD VYCPRHV+CT+EDMLNPNY+DLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LKV
Sbjct 3266 LDDTVYCPRHVVCTAEDMLNPNYDDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKV 3325
Query 3355 DTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFN 3414
DT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGFN
Sbjct 3326 DTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFN 3385
Query 3415 IDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAA 3474
IDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAA
Sbjct 3386 IDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAA 3445
Query 3475 VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKEL 3534
VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKEL
Sbjct 3446 VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKEL 3505
Query 3535 LQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVL 3594
LQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+L
Sbjct 3506 LQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLIL 3565
Query 3595 VQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVY 3654
VQSTQWSLFFF+YENAFLPFA+GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMVY
Sbjct 3566 VQSTQWSLFFFVYENAFLPFALGIMAVAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVY 3625
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNV 3714
MPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMNV
Sbjct 3626 MPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNV 3685
Query 3715 LTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGN 3774
+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITGN
Sbjct 3686 ITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGN 3745
Query 3775 TLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNS 3834
TLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+S
Sbjct 3746 TLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSS 3805
Query 3835 IDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQL 3894
IDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQL
Sbjct 3806 IDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQL 3865
Query 3895 HNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSY 3954
HNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSY
Sbjct 3866 HNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSY 3925
Query 3955 AAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYK 4014
AA+ATAQEAYEQAV+NGDSEVVLKKLKKSLNVAKSEFD DAAMQRKLEKMADQAMTQMYK
Sbjct 3926 AAYATAQEAYEQAVSNGDSEVVLKKLKKSLNVAKSEFDHDAAMQRKLEKMADQAMTQMYK 3985
Query 4015 QARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVI 4074
QARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV+
Sbjct 3986 QARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVV 4045
Query 4075 PDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN 4134
PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRAN
Sbjct 4046 PDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN 4105
Query 4135 SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN KGGRFVLALLSD QDLKWA
Sbjct 4106 SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNAKGGRFVLALLSDHQDLKWA 4165
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA
Sbjct 4166 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4225
Query 4255 GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA 4314
GNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA
Sbjct 4226 GNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA 4285
Query 4315 NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCG 4374
NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVCG
Sbjct 4286 NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCG 4345
Query 4375 MWKGYGCSCDQLREPMLQSADAQSFLN 4401
MWKGYGCSCDQLREPM+QSADA +FLN
Sbjct 4346 MWKGYGCSCDQLREPMMQSADASTFLN 4372
>sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus
Rp3/2004 OX=349344 GN=1a PE=3 SV=1
Length=4380
Score = 7445 bits (19316), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3519/4409 (80%), Positives = 3932/4409 (89%), Gaps = 41/4409 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK GTCG+VE+EKGV
Sbjct 1 MESLVLGINEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKSGTCGIVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQ EQPYVFIKRSDA+ HGH + ELVAEL+G+QYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQPEQPYVFIKRSDAQGTDHGHRVRELVAELDGVQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHS+G DLKS+DLGDELGTDP ED+++NWNTKH SGV REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGVLRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A TRYVDNNFCGPDGYPLECIKDLLARAGK+ CTLSEQLD+I++KRGVYCCR+H HEIAW
Sbjct 181 ALTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCRDHGHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TCGYL
Sbjct 301 RSVYPVATPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVSEGPNTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + E+GPEHS A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSAADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF+LNEE+AIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFQLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+ +S+L+PL F S+A
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPIKGAWNIGQHRSVLTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIFSRTL+ A +S+ LQ+AA+TILD IS+ SLRL+DAM++TS+L TN++++MAY
Sbjct 541 AGVIRSIFSRTLDAANHSIPDLQRAAVTILDSISEQSLRLVDAMVYTSNLLTNSVIIMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ TSQWL+N+ T EKL+P+ W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 VTGGLVQQTSQWLSNLLDTTVEKLRPIFAWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNIKDCVKCFVDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAVVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVCINGLMLLEIK E+YCAL+P ++ TNN F LKGGAPTK VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCINGLMLLEIKANEQYCALSPGLLATNNVFRLKGGAPTKGVTFGEDTVVEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEP--STQYEYGTEDDYQG 957
WS+AT+YLFD+SGE KL+S MYCSFYPPDE+E+ + EEEE + ++EYGTE+DY+G
Sbjct 901 WSVATFYLFDDSGEEKLSSRMYCSFYPPDEEEDCEEYEEEEEVSERTCEHEYGTEEDYKG 960
Query 958 KPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELT 1017
PLEFGA++ +Q EE++EEDWLDD + +
Sbjct 961 LPLEFGASTDIIQVEEQEEEDWLDDAVEAEPEPE-------------------------- 994
Query 1018 PVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
+ VN +GYLKLTDNV IK DIVEEA+ P V+VNAAN++LKHGGGVAGALNK
Sbjct 995 -PLHEEPVNQLTGYLKLTDNVAIKCVDIVEEAQNANPMVIVNAANIHLKHGGGVAGALNK 1053
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
ATN AMQ ESD YI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYEN
Sbjct 1054 ATNGAMQKESDHYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYEN 1113
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK 1197
FN ++LLAPLLSAGIFGA P+ SL++CV TVRT VY+ V DK LY+++V +L+ K
Sbjct 1114 FNSQDILLAPLLSAGIFGAKPLQSLQMCVQTVRTQVYIVVNDKVLYEQVVMDYLDSLKPK 1173
Query 1198 QVEQKIAEIPKEEVKP---FITESKPSVEQRKQDDK-KIKACVEEVTTTLEETKFLTENL 1253
E PK+EV P + + SV Q+ D K KIKAC++EVTTTLEETKFLT L
Sbjct 1174 ------VEAPKQEVLPKAEYPKVDEKSVVQKTIDVKPKIKACIDEVTTTLEETKFLTNKL 1227
Query 1254 LLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEML 1313
LL+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML
Sbjct 1228 LLFTDINGKLYQDSKNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEML 1287
Query 1314 AKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSW 1373
++AL+KVP + YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSW
Sbjct 1288 SRALKKVPINEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSETPNAKEEILGTVSW 1347
Query 1374 NLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVAS 1433
NLREMLAHAEETRKLMPVC++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS
Sbjct 1348 NLREMLAHAEETRKLMPVCMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVAS 1407
Query 1434 LINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSS 1493
+I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSS
Sbjct 1408 IITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAIVSVSSPDAVTTYNGYLTSS 1467
Query 1494 SKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVIT 1552
SKT E+HF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRG+K VY+T +P FHLDGEV+
Sbjct 1468 SKTSEDHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGEKIVYHTLESPVKFHLDGEVLP 1527
Query 1553 FDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNS 1612
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQ GPTYL+GADVTKIKPH +
Sbjct 1528 LDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQLGPTYLEGADVTKIKPHVN 1587
Query 1613 HEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADN 1672
HEGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADN
Sbjct 1588 HEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADN 1647
Query 1673 NCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETM 1732
NCYL++ LL LQQIE+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM
Sbjct 1648 NCYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETM 1707
Query 1733 SYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQ 1792
++L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+
Sbjct 1708 THLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKMGVSIPCVCGRD 1767
Query 1793 ATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGAL 1852
AT+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA
Sbjct 1768 ATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAH 1827
Query 1853 LTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPI 1912
LTK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPI
Sbjct 1828 LTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPI 1887
Query 1913 DLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDY 1972
DL+P QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY
Sbjct 1888 DLIPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDY 1947
Query 1973 KHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSED 2032
+HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1948 RHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVED 2007
Query 2033 AQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGH 2092
QGMDNLACE +P EEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+ H
Sbjct 2008 TQGMDNLACESQQPTPEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELDH 2067
Query 2093 TDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVST 2152
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + T
Sbjct 2068 EDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWGKILAYVKPFLGQAAVT 2127
Query 2153 TTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLE 2212
T+N R + R+ NYMPY TLL QLCTFT+STNSRI+AS+PTTIAKN+V+ + + CL+
Sbjct 2128 TSNCAKRLVQRMFNNYMPYVLTLLFQLCTFTKSTNSRIRASLPTTIAKNSVRGIVRLCLD 2187
Query 2213 ASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLN 2272
A NY+KSP FSKL I +W LLLS+CLGSLIY TAALGVL+SN G PSYC+G RE YLN
Sbjct 2188 AGINYVKSPKFSKLFTIAMWLLLLSICLGSLIYVTAALGVLLSNFGAPSYCSGVRESYLN 2247
Query 2273 STNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYI 2332
S+NVT +C GS PCSVCLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEWF AY+
Sbjct 2248 SSNVTTMDFCEGSFPCSVCLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWFFAYM 2307
Query 2333 LFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYY 2392
LFT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY
Sbjct 2308 LFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYY 2367
Query 2393 VWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNC 2452
+WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC
Sbjct 2368 IWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNC 2427
Query 2453 VNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKT 2512
+NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSY+VDSV VKNG++HLYFDKAGQKT
Sbjct 2428 LNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAGQKT 2487
Query 2513 YERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLL 2572
YERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES+AKSASVYYSQLMCQPILLL
Sbjct 2488 YERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPILLL 2547
Query 2573 DQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLST 2632
DQALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLST
Sbjct 2548 DQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLST 2607
Query 2633 FISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACI 2692
F+SA+RQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACI
Sbjct 2608 FVSASRQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACI 2667
Query 2693 DCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVN 2752
DC+ARHINAQVA+SHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVN
Sbjct 2668 DCNARHINAQVARSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVN 2727
Query 2753 VVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAI 2812
V+TTKI+LKGGKIV+ W K ++K TL+ + A + Y++ PVH++S H +++EIIGYKAI
Sbjct 2728 VITTKISLKGGKIVSTWFKIMLKATLLCVLAALVCYIVMPVHILSVHGGYTNEIIGYKAI 2787
Query 2813 DGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGT 2872
GVTRDI STD CFANKHA FD+WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT
Sbjct 2788 QDGVTRDIVSTDDCFANKHAGFDSWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGT 2847
Query 2873 ILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPY 2932
+LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DF+TSACVLAAECTIFKDA GKPVPY
Sbjct 2848 VLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFSTSACVLAAECTIFKDAMGKPVPY 2907
Query 2933 CYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERS 2992
CYDTN+LEGS++Y LRPDTRYVLMDGSIIQFPN YLEGSVRVVTTFD+EYCRHGTCERS
Sbjct 2908 CYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNAYLEGSVRVVTTFDAEYCRHGTCERS 2967
Query 2993 EAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGI 3052
EAG+C+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI
Sbjct 2968 EAGICLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGI 3027
Query 3053 VAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYL 3112
+AI+VTC AYYFM+FRRAFGEY+HVVA N LFLMSFT+LCL P YSFLPGVYSV YLYL
Sbjct 3028 IAILVTCAAYYFMKFRRAFGEYNHVVAANAPLFLMSFTILCLAPAYSFLPGVYSVFYLYL 3087
Query 3113 TFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSF 3172
TFY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KHF+WFF+NYL++RVVFNGV+F
Sbjct 3088 TFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHFHWFFNNYLRKRVVFNGVTF 3147
Query 3173 STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACC 3232
STFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACC
Sbjct 3148 STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACC 3207
Query 3233 HLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG 3292
HLAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG
Sbjct 3208 HLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG 3267
Query 3293 LWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKL 3352
LWLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+L
Sbjct 3268 LWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRL 3327
Query 3353 KVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVG 3412
KVDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVG
Sbjct 3328 KVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVG 3387
Query 3413 FNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLY 3472
FNIDYDCVSFCYMHHMELPT VHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLY
Sbjct 3388 FNIDYDCVSFCYMHHMELPTEVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLY 3447
Query 3473 AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLK 3532
AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LK
Sbjct 3448 AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALK 3507
Query 3533 ELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLL 3592
ELLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ KR +KGTHHW+LLT LTSLL
Sbjct 3508 ELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKRIVKGTHHWMLLTFLTSLL 3567
Query 3593 VLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNM 3652
+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNM
Sbjct 3568 ILVQSTQWSLFFFVYENAFLPFTLGIMAVAACAMLLVKHKHAFLCLFLLPSLATVAYFNM 3627
Query 3653 VYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLM 3712
VYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL+LMTARTVYDD ARRVWTLM
Sbjct 3628 VYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVWTLM 3687
Query 3713 NVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFIT 3772
NV+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FIT
Sbjct 3688 NVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFIT 3747
Query 3773 GNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK 3832
GNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK
Sbjct 3748 GNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK 3807
Query 3833 NSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV 3892
+SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV
Sbjct 3808 SSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV 3867
Query 3893 QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP 3952
QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP
Sbjct 3868 QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP 3927
Query 3953 SYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQM 4012
SYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR+AAMQRKLEKMADQAMTQM
Sbjct 3928 SYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRNAAMQRKLEKMADQAMTQM 3987
Query 4013 YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV 4072
YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV
Sbjct 3988 YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV 4047
Query 4073 VIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALR 4132
V+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+M+NS NLAWPLIVTALR
Sbjct 4048 VVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMENSSNLAWPLIVTALR 4107
Query 4133 ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLK 4192
ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLK
Sbjct 4108 ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLK 4167
Query 4193 WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRL 4252
WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL+FIKGLNNLNRGMVLGSLAATVRL
Sbjct 4168 WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLHFIKGLNNLNRGMVLGSLAATVRL 4227
Query 4253 QAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP 4312
QAGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP
Sbjct 4228 QAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP 4287
Query 4313 EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTV 4372
EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTV
Sbjct 4288 EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTV 4347
Query 4373 CGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
CGMWKGYGCSCDQLREPM+QSADA +FLN
Sbjct 4348 CGMWKGYGCSCDQLREPMMQSADASTFLN 4376
>sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus
279/2005 OX=389167 GN=1a PE=3 SV=1
Length=4388
Score = 7442 bits (19309), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3523/4412 (80%), Positives = 3924/4412 (89%), Gaps = 39/4412 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESL G +EKTHVQLSLPVLQVRDVLVRGFGDSVEE L+EAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLALGVSEKTHVQLSLPVLQVRDVLVRGFGDSVEEALAEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA+ HG+ +VELVAEL+GIQYGRSG TLGVLVPHVGE PVAYR
Sbjct 61 LPQLEQPYVFIKRSDAQGTNHGYKVVELVAELDGIQYGRSGTTLGVLVPHVGETPVAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLG ELGTDP ED+++NWNTKH GV REL+RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGVELGTDPIEDYEQNWNTKHGGGVLRELIRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A+TRYVDNNFCGPDGYPLECIKDLLARAGK+ CTLSEQLD+I++KRGVYCCREHEHEI W
Sbjct 181 AFTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERSEKSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSEKSYERQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + EVGPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PANAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIG +HTG+ G+ E LN++L+EIL +++VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASANIGASHTGITGDNVETLNEDLMEILNRDRVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SAST AFV+TVKGLDYK FK IVESCGNFKVT+G+AKKGAWNIG++KSIL+PLY F S+A
Sbjct 481 SASTCAFVDTVKGLDYKTFKDIVESCGNFKVTRGRAKKGAWNIGQEKSILTPLYGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIF+R L+TA +S+ LQ+AAITILDGIS+ SLRLIDAM++TSDL TN+++VMAY
Sbjct 541 AGVIRSIFTRALDTANHSIPDLQRAAITILDGISEQSLRLIDAMVYTSDLLTNSVIVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ +QWL+N+ GT +KLKPV W+E K G+EFLRD WEI+KF+ T +IV
Sbjct 601 VTGGLVQQITQWLSNMLGTTVDKLKPVFTWVEAKLSAGIEFLRDAWEILKFLVTGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + +KE V+ F ++NK L +C D +II GAKL+ LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNLKECVKAFLDVLNKALEMCIDQVIIAGAKLRTLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPL+APKE+ F EG++ T +EEVVLK G+L+ LE P ++G
Sbjct 721 IRGKEQLQLLMPLRAPKEVTFFEGDSHDTVFTSEEVVLKNGELEALETPVDSFTNGAVIG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVC+NGLMLLE+KD E+YCAL+P ++ TNN F+LKGGAP K VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCVNGLMLLELKDKEQYCALSPGLLATNNVFSLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 KITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ--YEYGTEDDYQG 957
WS+AT+YLFD++GE KL+S MYCSFYPPDE+E+ + E+EE P +EYGTEDDY+G
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCEEYEDEEEIPEETCEHEYGTEDDYKG 960
Query 958 KPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELT 1017
PLEFGA++ + QQ +++ + + E
Sbjct 961 LPLEFGAST----------------EIQQVDEEEEEDWLEEAIAAKPEPEPL-------- 996
Query 1018 PVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
VN F+GYLKLTDNV IK DIV+EA+ KPTV+VNAANV+LKHGGGVAGALNK
Sbjct 997 ---PEEPVNQFTGYLKLTDNVAIKCVDIVKEAQHAKPTVIVNAANVHLKHGGGVAGALNK 1053
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
ATN AMQ ESDDYI NGPL VGGSC+LSGHNLAK C+HVVGPN+N GED+QLLK+AY N
Sbjct 1054 ATNGAMQQESDDYIKKNGPLTVGGSCLLSGHNLAKKCMHVVGPNLNAGEDVQLLKAAYAN 1113
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK 1197
FN +VLLAPLLSAGIFGA P+ SL++CV+TVRT VY AV D++LYD +V +L+ K
Sbjct 1114 FNSQDVLLAPLLSAGIFGAKPLQSLKMCVETVRTQVYFAVNDQDLYDHVVLGYLDSLKPK 1173
Query 1198 QVE---QKIAEIPKEEVKPFITESKPSVEQ----RKQDDKKIKACVEEVTTTLEETKFLT 1250
VE Q+ E+ ++ +T+ +E+ K D K KA +EEV T+LEETKFLT
Sbjct 1174 -VETPTQENLELKEQPAVETLTQENLELEELPVIEKPVDVKFKARIEEVNTSLEETKFLT 1232
Query 1251 ENLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTT 1310
LLL+ DING L+ DS ++ D+ FL+KDAPYIVGDV+ G +T V+IP KKAGGTT
Sbjct 1233 SRLLLFADINGKLYQDSQNMLRGEDMFFLEKDAPYIVGDVISSGDITCVIIPAKKAGGTT 1292
Query 1311 EMLAKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGT 1370
EMLAKAL+KVP YITTYPGQG GYT+EEAKT L+KCKS FY+LPS N+K+EILGT
Sbjct 1293 EMLAKALKKVPVSEYITTYPGQGCAGYTLEEAKTALRKCKSVFYVLPSKTPNDKEEILGT 1352
Query 1371 VSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTT 1430
VSWNLREMLAHAEETRKLM +C++ KA++STI R+YKGIK+QEG+VDYG RF+FYTSK
Sbjct 1353 VSWNLREMLAHAEETRKLMLICMDVKALMSTIHRRYKGIKVQEGIVDYGVRFFFYTSKEP 1412
Query 1431 VASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYL 1490
VAS+I LN LNE LVTMP+GYVTHGLNLEEAAR MRSLK PA VSVSSPDAVT YNGYL
Sbjct 1413 VASIITKLNLLNEPLVTMPIGYVTHGLNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYL 1472
Query 1491 TSSSKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGE 1549
TSSSKT EEHFIET+SLAG Y+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGE
Sbjct 1473 TSSSKTSEEHFIETVSLAGMYRDWSYSGQRTELGVEFLKRGDKVVYHTVGSPIQFHLDGE 1532
Query 1550 VITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKP 1609
V+ D LK+LLSLREVRTIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKP
Sbjct 1533 VLLLDKLKSLLSLREVRTIKVFTTVDNTNLHTQIVDMSMTYGQQFGPTYLDGADVTKIKP 1592
Query 1610 HNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKW 1669
H HEGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQ+ GLTSIKW
Sbjct 1593 HAKHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQIGGLTSIKW 1652
Query 1670 ADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVR 1729
ADNNCYL++ LL LQQIE+KFN PALQ+AYYRARAG+AANFCALILAY N+TVGELGDVR
Sbjct 1653 ADNNCYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAYSNRTVGELGDVR 1712
Query 1730 ETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTC 1789
ETM++L QHANL+S KRVLNVVCKTCGQ+ TTL GVEAVMYMGTLSYE+ K GV IPC C
Sbjct 1713 ETMTHLLQHANLESAKRVLNVVCKTCGQKSTTLTGVEAVMYMGTLSYEELKTGVTIPCIC 1772
Query 1790 GKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCID 1849
G+ AT+YLVQQES FVMMSAPP++Y L+ G F CA+EYTG+YQCGHY H+T KETLY ID
Sbjct 1773 GRDATQYLVQQESSFVMMSAPPSEYTLQQGAFLCANEYTGSYQCGHYTHVTVKETLYRID 1832
Query 1850 GALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTE 1909
GA LTK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV+ TEI PKLD YYKKDN+Y+TE
Sbjct 1833 GAYLTKMSEYKGPVTDVFYKEISYTTTIKPVSYKLDGVIYTEIQPKLDEYYKKDNAYYTE 1892
Query 1910 QPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVA 1969
QPIDLVP QP PNASFDNFK C N KFADDLNQ+TG+KKPASREL VTFFPDLNGDVVA
Sbjct 1893 QPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFKKPASRELSVTFFPDLNGDVVA 1952
Query 1970 IDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLK 2029
IDY+HY+ SFKKGAKLLHKPI+WH+N TNK TYKPNTWC+RCLWSTKPVETSNSF+VL+
Sbjct 1953 IDYRHYSASFKKGAKLLHKPIIWHINQTTNKTTYKPNTWCLRCLWSTKPVETSNSFEVLE 2012
Query 2030 SEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEE 2089
ED QGMDNLACE P SEEVVENPTIQK+V+EC+VKT EVVG++ILKP+ +K+T+E
Sbjct 2013 VEDTQGMDNLACESQTPTSEEVVENPTIQKEVIECDVKTIEVVGNVILKPSEEGVKVTQE 2072
Query 2090 VGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKV 2149
+GH DLMAAYV+ +S+TIKKPNELS LGL+TLATHG AA+NSVPW I Y KPFL +
Sbjct 2073 LGHEDLMAAYVEETSITIKKPNELSLALGLRTLATHGAAAINSVPWSKILAYVKPFLGQA 2132
Query 2150 VSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKF 2209
TTTN + RC+ RV NYMPY TLL QLCTFTRSTNSRI+AS+PTTIAKN+VKSV K
Sbjct 2133 AVTTTNCIKRCVQRVFNNYMPYVITLLFQLCTFTRSTNSRIRASLPTTIAKNSVKSVAKL 2192
Query 2210 CLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREG 2269
CL+ NY+KSP FSKL I +W LLLS+CLGSLIY TAA GVL+SNLG+PSYC G RE
Sbjct 2193 CLDVCINYVKSPKFSKLFTIAMWLLLLSICLGSLIYVTAAFGVLLSNLGIPSYCDGVRES 2252
Query 2270 YLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFL 2329
Y+NS+NVT +C GS CSVCL+GLDSLD+YP+LETIQ+TISS+K DLT+ GL AEWFL
Sbjct 2253 YVNSSNVTTMDFCEGSFLCSVCLNGLDSLDSYPALETIQVTISSYKLDLTSLGLAAEWFL 2312
Query 2330 AYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFAS 2389
AY+LFT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFA
Sbjct 2313 AYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFAF 2372
Query 2390 FYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHN 2449
YYVWKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HN
Sbjct 2373 CYYVWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKAHN 2432
Query 2450 WNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAG 2509
WNC+NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSY+VDSV VKNG++HLYFDKAG
Sbjct 2433 WNCLNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAG 2492
Query 2510 QKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPI 2569
QKTYERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES+AKSASVYYSQLMCQPI
Sbjct 2493 QKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPI 2552
Query 2570 LLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNV 2629
LLLDQALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD V
Sbjct 2553 LLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGV 2612
Query 2630 LSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLG 2689
LSTF+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLG
Sbjct 2613 LSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLG 2672
Query 2690 ACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQ 2749
ACIDC+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQ
Sbjct 2673 ACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQ 2732
Query 2750 VVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGY 2809
VVN +TTKI+LKGGKIV+ W K ++K TL+ + A Y+I PVH +S H +++EIIGY
Sbjct 2733 VVNAITTKISLKGGKIVSTWFKLMLKATLLCVLAALFCYIIMPVHSLSVHDGYTNEIIGY 2792
Query 2810 KAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGL 2869
KAI GVTRDI +TD CFANKHA FD+WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGL
Sbjct 2793 KAIQDGVTRDIMATDDCFANKHAGFDSWFSQRGGSYRNDKSCPVVAAIITREIGFIVPGL 2852
Query 2870 PGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKP 2929
PGT+LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKP
Sbjct 2853 PGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKP 2912
Query 2930 VPYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTC 2989
VPYCYDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTC
Sbjct 2913 VPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTC 2972
Query 2990 ERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVA 3049
ERSEAGVC+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VA
Sbjct 2973 ERSEAGVCLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVA 3032
Query 3050 GGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIY 3109
GGI+AI+VTC AYYFM+FRRAFGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYS+ Y
Sbjct 3033 GGIIAILVTCAAYYFMKFRRAFGEYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFY 3092
Query 3110 LYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNG 3169
LYLTFY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNG
Sbjct 3093 LYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNG 3152
Query 3170 VSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREA 3229
V+FSTFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREA
Sbjct 3153 VTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREA 3212
Query 3230 ACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT 3289
ACCHLAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT
Sbjct 3213 ACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT 3272
Query 3290 LNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCV 3349
LNGLWLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+
Sbjct 3273 LNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCL 3332
Query 3350 LKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCG 3409
L+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN+TIKGSFLNGSCG
Sbjct 3333 LRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNYTIKGSFLNGSCG 3392
Query 3410 SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLA 3469
SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLA
Sbjct 3393 SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLA 3452
Query 3470 WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA 3529
WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA
Sbjct 3453 WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA 3512
Query 3530 SLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILT 3589
+LKELLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LT
Sbjct 3513 ALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLT 3572
Query 3590 SLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAY 3649
SLL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAY
Sbjct 3573 SLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAY 3632
Query 3650 FNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVW 3709
FNMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL+LMTARTVYDD ARRVW
Sbjct 3633 FNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVW 3692
Query 3710 TLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIF 3769
TLMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+
Sbjct 3693 TLMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLL 3752
Query 3770 FITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL 3829
FITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL
Sbjct 3753 FITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL 3812
Query 3830 PPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA 3889
PPK+SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA
Sbjct 3813 PPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA 3872
Query 3890 QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFS 3949
QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFS
Sbjct 3873 QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFS 3932
Query 3950 SLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM 4009
SLPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM
Sbjct 3933 SLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM 3992
Query 4010 TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK 4069
TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK
Sbjct 3993 TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK 4052
Query 4070 LMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVT 4129
LMVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNS NLAWPLIVT
Sbjct 4053 LMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSQNLAWPLIVT 4112
Query 4130 ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQ 4189
ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD Q
Sbjct 4113 ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQ 4172
Query 4190 DLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAAT 4249
DLKWARFPKSDGTGTIYTELEPPCRFVTDTP+GPKVKYLYFIKGLNNLNRGMVLGSLAAT
Sbjct 4173 DLKWARFPKSDGTGTIYTELEPPCRFVTDTPRGPKVKYLYFIKGLNNLNRGMVLGSLAAT 4232
Query 4250 VRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT 4309
VRLQAGNATEVPANS VLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT
Sbjct 4233 VRLQAGNATEVPANSAVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT 4292
Query 4310 VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIP TCANDPVGFTLKNTV
Sbjct 4293 VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPATCANDPVGFTLKNTV 4352
Query 4370 CTVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
CTVCG WKGYGCSCDQLREPM+QSADA +FLN
Sbjct 4353 CTVCGTWKGYGCSCDQLREPMMQSADASTFLN 4384
>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930
Score = 6357 bits (16492), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3387/7182 (47%), Positives = 4510/7182 (63%), Gaps = 421/7182 (6%)
Query 28 VRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV--LPQLEQPYVFIKRSDARTAPHG-HV 84
V G+ +EE L A+Q L+ LV V + P + V I S G
Sbjct 29 VTGWDIPIEEALEYAKQQLRTPEPQLVFVPYYLSHAPGISGDRVVITDSIWYATNFGWQP 88
Query 85 MVELVAELEGIQYGRSGETLGVLVPH------VGEIPVAYRKVLLRKNGNKGAGGHSYGA 138
+ EL + +G++YGR G T GVL+P +G+I + RK G G +S
Sbjct 89 IRELAMDKDGVRYGRGG-THGVLLPMQDPSFIMGDIDIQIRKY--------GIGANSPPD 139
Query 139 DLKSFDLGDELGTD--PYEDFQENW-NTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
L +D + G D PY DF +N TK + ++ G DNN G
Sbjct 140 VLPLWDGFSDPGPDVGPYLDFPDNCCPTKPKAKRGGDVYLSDQYG-----FDNN-----G 189
Query 196 YPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPF 255
+E + LL K+ TL + L + G Y R+E Y+L +
Sbjct 190 ILVEPVMKLLGVI-KSDFTLEQLLAAL----GKY--------------RTEDGYDLPDGY 230
Query 256 ---EIKLAKK------------FDTFNGECPNFVFPLN--SIIKTIQPRVEKKKLDGFMG 298
IK+ +K P + +P + S+++ +P
Sbjct 231 VKVAIKVGRKAVPVLKQSIFTVVGVTEQLVPGYYYPFSTSSVVEHTKPTRGGPVGKTVEA 290
Query 299 RIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTE-NLTKEGATTC 357
+ S+Y N N +KC +C W + CG E LT ++C
Sbjct 291 VMLSLY---GTNNYNPATPVARLKCSYCDYYGWTPLKDIGTVNCLCGAEFQLT----SSC 343
Query 358 GYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRT-IAFGGCVFSYVGC 416
V+K P C + G++ I G RT ++FGG ++S +G
Sbjct 344 VDAESAGVIK---PGC----------VMLLDKSPGMRLI--PGNRTYVSFGGAIWSPIGK 388
Query 417 HNKCAYWVPRASANIGCNHTGVVGEG-SEGLNDNLLEILQKEKVNINIVGDFKLNEEIAI 475
N WVPRA + + H+G VG G + +N L+E L + I + D N A
Sbjct 389 VNGVTVWVPRAYSIVAGEHSGAVGSGDTVAINKELVEYLIE---GIRVDADTLDNPTCAT 445
Query 476 ILASFSASTSA----FVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILS 531
+A+ T A VE+++GL C K+ G E +
Sbjct 446 FIANLDCDTKAPVVHTVESLQGL-----------CLANKIMLGDKP---LPTDEFHPFIV 491
Query 532 PLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLA 591
L A+ + A ++ SRT E ++ VR ++ +Q+ ++ +
Sbjct 492 GL-AYHVQRACWYGALASRTFEAFRDFVRTEEER-------FAQFFGKVCAPI------- 536
Query 592 TNNLVVMAYITGGVVQLTSQWLTN------------IFGTVYEKLKPVLDWLEEKFKEGV 639
N V +AY TG V ++ + N + V + LKP+L+W+ +K +
Sbjct 537 -NGCVYLAYTTGRVTLFSAYQVLNTAIAKSKDAFGGVAAIVVDMLKPILEWVLKK----M 591
Query 640 EFLRDGW----EIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIII 695
+ W E + + +V G+ + + L+ ++ S+
Sbjct 592 SIAKGAWLPYAEGLLALFKAQFTVVKGKFQFLRASLNSKCHSLCDLLTTIMSKLLTSVKW 651
Query 696 GGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLM-PLKAPKEIIFLEGETLPTEVLTE 754
G K+ AL G + KG+ + + GLL+ P + E+ L+G+ LT+
Sbjct 652 AGCKVDALYTGTYYYFSRKGVLTEVQLCAKRLGLLLTPKQQKMEVEVLDGDFDAPVTLTD 711
Query 755 EVVLKTGDLQPLEQPTSEAVEAPLV-GTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTF 813
L+ + + + A + LV GT V + + + +D Y + V F
Sbjct 712 ---LELEECTGVLEEVFGASDVKLVKGTLVSLASKLFVRTEDGFLY-RYVKSGGVLGKAF 767
Query 814 TLKGGAPTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFAC 873
L+GG +KVTFGD+ V + +VN ++++ E +D +L++ + + VE GT++ + AC
Sbjct 768 RLRGGGVSKVTFGDEEVHTIPNTVTVNFSYDVCEGLDAILDKVMAPFQVEEGTKLEDLAC 827
Query 874 VVADAVIKTLQPV----SELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYP--P 927
VV AV + L + L P I+L+++ + +++ + E L MY S P
Sbjct 828 VVQKAVYERLSDLFSDCPAELRP--INLEDFLTSECFVYSKDYEKILMPEMYFSLEDAVP 885
Query 928 DEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQT 987
+DE D E+ ++ + ++ WL D
Sbjct 886 VDDEMVDDIED-----------------------------TVEQASDSDDQWLGD----- 911
Query 988 VGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVE 1047
+G+ED TI +V M TP GY K+ ++VYIK ADIV+
Sbjct 912 ----EGAEDCD----NTIQDVDVATSMT-TP----------CGYTKIAEHVYIKCADIVQ 952
Query 1048 EAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSG 1107
EA+ V+VNAANV L HGGGVAGALN+ATNNAMQ ES +YI NG L+ GG +LS
Sbjct 953 EARNYSYAVLVNAANVNLHHGGGVAGALNRATNNAMQKESSEYIKANGSLQPGGHVLLSS 1012
Query 1108 HNLAKH-CLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCV 1166
H LA H LHVVGP+ G+D+ LL + Y + + +L PL+SAGIFG SL V
Sbjct 1013 HGLASHGILHVVGPDKRLGQDLALLDAVYAAYTGFDSVLTPLVSAGIFGFTVEESLCSLV 1072
Query 1167 DTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRK 1226
V Y+ V+D+ LY++ +++ ++ + Q + I E E + S+ +
Sbjct 1073 KNVACTTYVVVYDRQLYERALATSFDVPGPQSSVQHVPAIDWAEA----VEVQESIVDQV 1128
Query 1227 QDDK--KIKACVEEVTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDITFLKKDAP 1284
+ + + L ET EN++ + PD +V+D++
Sbjct 1129 ETPSLGAVDTVDSNADSGLNETARSPENVVGSV-------PDD--VVADVE--------- 1170
Query 1285 YIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKVPTDNYITTYPGQGLNGYTVEEAKT 1344
V D+V++ V +KV D P + TVE+
Sbjct 1171 SCVRDLVRQVV----------------------KKVKRDK----RPPPIVPQQTVEQQPQ 1204
Query 1345 VLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQR 1404
+ +L ++S + M+ +E L+PV ++ A + ++R
Sbjct 1205 EISSPGDCNTVLVDVVS-----------MSFSAMVNFGKEKGLLIPVVIDYPAFLKVLKR 1253
Query 1405 KYKGIKIQEGVVDY-GARFYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAA 1463
+EG+ G FY Y+ + + LN L L+ +P G++ +G L +A
Sbjct 1254 ----FSPKEGLFSSNGYEFYGYSRDKPLHEVSKDLNSLGRPLIMIPFGFIVNGQTLAVSA 1309
Query 1464 RYMRSLKVPATVSVSSPDAVTAYNGYLT---SSSKTPEEHFIETISLAGSYKDWSYSGQS 1520
MR L VP TV V S +V Y Y S T + F+ I L G+ +DW +
Sbjct 1310 VSMRGLTVPHTVVVPSESSVPLYRAYFNGVFSGDTTAVQDFVVDILLNGA-RDWDVLQTT 1368
Query 1521 TQLGIE----FLKRGDKSVYYTSNPTTFHLDGEVI-TFDNLKTLLSLREVR------TIK 1569
+ + KRG+ + + + + + G+V+ F + + E + IK
Sbjct 1369 CTVDRKVYKTICKRGNTYLCF-DDTNLYAITGDVVLKFATVSKARAYLETKLCAPEPLIK 1427
Query 1570 VFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRV 1629
V TTVD IN T +V + +Y Q G + DG D + P + EG Y N + V
Sbjct 1428 VLTTVDGINYSTVLVSTAQSYRAQIGTVFCDGHDWSNKNPMPTDEGTHLYKQDNFSSAEV 1487
Query 1630 EAF-EYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIEL 1688
A EYY D + + R MS + W Y V+G + D+NCYL A+ LQ I++
Sbjct 1488 TAIREYYGVDDSNIIARAMSIRKTVQTWPYTVVDGRVLLAQRDSNCYLNVAISLLQDIDV 1547
Query 1689 KFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVL 1748
F+ P + AY + G +++A T G D +S + H + + +RV+
Sbjct 1548 SFSTPWVCRAYDALKGGNPLPMAEVLIALGKATPGVSDDAHMVLSAVLNHGTV-TARRVM 1606
Query 1749 NVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMS 1808
VC+ CG Q G +A + G++ + V + C CG+ A +Y+ +Q+SP+++MS
Sbjct 1607 QTVCEHCGVSQMVFTGTDACTFYGSVVLDDLYAPVSVVCQCGRPAIRYVSEQKSPWLLMS 1666
Query 1809 APPAQYELK-HGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
P Q L G + A + G GHY + + + D ++S+ K P TD+
Sbjct 1667 CTPTQVPLDTSGIWKTAIVFRGPVTAGHYMYAVNGTLISVYDANTRRRTSDLKLPATDIL 1726
Query 1868 YKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPNASFDN 1927
Y S+T+ K TY LDGV T IDP Y K+ + YFT PI++V P S+D
Sbjct 1727 YGPTSFTSDSKVETYYLDGVKRTTIDPDFSKYVKRGDYYFTTAPIEVVA-APKLVTSYDG 1785
Query 1928 FKF-VCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLL 1986
F C N + A+ N+ K +L +T +P++ GDVVAI + + G+ +
Sbjct 1786 FYLSSCQNPQLAESFNKAINATKTGPMKL-LTMYPNVAGDVVAISDDNVV-AHPYGSLHM 1843
Query 1987 HKPIVWHVNNATNKATYKPNTW-CIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLK 2045
KP+++ +PNTW + L ST V T N++DVL D
Sbjct 1844 GKPVLF---------VTRPNTWKKLVPLLSTVVVNTPNTYDVLAV------------DPL 1882
Query 2046 PVSEEVVENP-TIQKDVLECNVKTTEVVGDIILKPANNS-LKITEEVGHTDLMAAYVDN- 2102
PV+ E E P +++ + +K T V+ P N L +E TDL YV+
Sbjct 1883 PVNNETSEEPISVKAPIPLYGLKATMVLNGTTYVPGNKGHLLCLKEFTLTDLQTFYVEGV 1942
Query 2103 SSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT--NIVTRC 2160
+ K + LS+VLGL+ + VN + + YA L V+T+ +VTR
Sbjct 1943 QPFVLLKASHLSKVLGLRV--SDSSLHVNHLSKGVVYAYAATRLTTRVTTSLLGGLVTRS 2000
Query 2161 LNRV------------CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGK 2208
+ + C + F+ L ++ + +K S IA NT V
Sbjct 2001 VRKTADFVRSTNPGSKCVGLLCLFYQLFMRFWLLVKKP-PIVKVS--GIIAYNTGCGVTT 2057
Query 2209 FCLEASFNYLKSP----NFSKLINII-----IWFLL--LSVCLGSLIYSTAALGVLMSNL 2257
L NYL+S ++S+L+ ++ IWF+ L++C GV +S
Sbjct 2058 CVL----NYLRSRCGNISWSRLLKLLRYMLYIWFVWTCLTIC-----------GVWLSEP 2102
Query 2258 GMPSYCTGYRE--GYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFK 2315
PS T ++ G + + + +C++G+DSLD YP+L Q S
Sbjct 2103 YAPSLVTRFKYFLGIVMPCDYVLVNETGTGWLHHLCMAGMDSLD-YPALRMQQHRYGS-P 2160
Query 2316 WDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMA 2375
++ T ++ E F AY+L+T ++G+ A++ L Y + + NSWL+ + ++++
Sbjct 2161 YNYTYILMLLEAFFAYLLYTPALPIVGILAVLHLIVLYLPIP-LGNSWLVVFLYYIIRLV 2219
Query 2376 PISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFY 2435
P ++M+RMYI A + +K ++HV GCN+ C+MCYK+N A R+EC+T+VNGV+R FY
Sbjct 2220 PFTSMLRMYIVIAFLWLCYKGFLHVRYGCNNVACLMCYKKNVAKRIECSTVVNGVKRMFY 2279
Query 2436 VYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVT 2495
V ANGG FC HNWNCV+CDT+ STFI +VA DLS QFKRPI TD++ Y V SV
Sbjct 2280 VNANGGTHFCTKHNWNCVSCDTYTVDSTFICRQVALDLSAQFKRPIIHTDEAYYEVTSVE 2339
Query 2496 VKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLP-INVIVFDGKSKCEESSA 2554
V+NG ++ YF+ GQ++YER + F N+ L + KG+ P NV+VFD ++ EE++
Sbjct 2340 VRNGYVYCYFESDGQRSYERFPMDAFTNVSKLHYSELKGAAPAFNVLVFDATNRIEENAV 2399
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
K+A++YY+QL C+PILL+D+ +V VGD A +A MF+AY + +++ M+K+K L +
Sbjct 2400 KTAAIYYAQLACKPILLVDKRMVGVVGDDATIARAMFEAYAQNYLLKYSIAMDKVKHLYS 2459
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGFVD--SDVETKDVVECLKLSHQSDIEVTGDSCNN 2672
TA +++ +++++VL F+ + R D SDV+T D+V C++L HQ E T DS NN
Sbjct 2460 TALQQISSGMTVESVLKVFVGSTRAEAKDLESDVDTNDLVSCIRLCHQEGWEWTTDSWNN 2519
Query 2673 YMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSA 2732
+ TY K + ++ ++G + +A+++NA +AK + LIW DF+ LSE +R+Q++ A
Sbjct 2520 LVPTYIKQDTLSTLEVGQFMTANAKYVNANIAKGAAVNLIWRYADFIKLSESMRRQLKVA 2579
Query 2733 AKKNNLPFKLTCATTRQVVNVVTTKIALKGG-KIVNNWLKQLIKVTLVFLFVAAIFYLIT 2791
A+K L +T ++ + V + T + GG + + +W + LI V ++ + + ++ T
Sbjct 2580 ARKTGLNLLVTTSSLKADVPCMVTPFKIIGGHRRIVSWRRVLIHVFMLLVVLNPQWF--T 2637
Query 2792 PVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKAC 2851
P ++M ++ +K ID V RDI S D CFANK + F+ W+S R GSY N + C
Sbjct 2638 PWYIMRP---IEYNVVDFKVIDNAVIRDITSADQCFANKFSAFENWYSNRYGSYVNSRGC 2694
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ V++ VG +VPGLP LR L + AVG++CYTP I Y F TS
Sbjct 2695 PMVVGVVSDIVGSLVPGLPARFLRVGT-TLLPLVNYGLGAVGSVCYTPHYAINYDVFDTS 2753
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
ACVLAA CT+F ASG+ +PYC D +++ + Y+ L+P Y + S I+FP +
Sbjct 2754 ACVLAATCTLFSSASGERMPYCADAALIQNASRYDMLKPHVMYPFYEHSGYIRFPEV-IS 2812
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
V +V T EYC+ G C+ SEAG+C+S RWV+NN Y+R GV+CG A +L NM
Sbjct 2813 AGVHIVRTMAMEYCKVGRCDVSEAGLCMSLQPRWVVNNAYFRQQSGVYCGTSAFDLFMNM 2872
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
P+ P+GA+DI+ SI+ G ++A+VV+ YY +RFRRAFG+YS V+ N L F+++
Sbjct 2873 LLPIFTPVGAVDITTSILMGALLAVVVSMSLYYLLRFRRAFGDYSGVIFTNILAFVLNVI 2932
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
VLCL Y LP +Y++++LY T Y +D++ + H+ +++MF +VP W+T+ YI+ + +
Sbjct 2933 VLCLEGPYPMLPSIYAMVFLYATCYFGSDIACMMHVSFLIMFAGVVPLWVTVLYIVVVLS 2992
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
+H WF S KR V ++F +F++AAL TF+L+KE++L+L+ ++ Y +YLA+
Sbjct 2993 RHILWFASLCTKRTVQVGDLAFHSFQDAALQTFMLDKEVFLRLKREI--SSDAYFKYLAM 3050
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMA 3270
YNKYKY+SG MDT +YREAAC HL AL +SN G D +YQPP+ S+ SA LQ+G +MA
Sbjct 3051 YNKYKYYSGPMDTAAYREAACSHLVMALEKYSNGGGDTIYQPPRCSVASAALQAGLTRMA 3110
Query 3271 FPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFL 3330
PSG VE C+V+V G+ TLNG+WLD+ V CPRHV+C+ +++ NP+Y L +R +N++F
Sbjct 3111 HPSGLVEPCLVKVNYGSMTLNGIWLDNFVICPRHVMCSRDELANPDYPRLSMRAANYDFH 3170
Query 3331 VQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQ 3390
V +RVIGH+M+ +LKL VD NPKTP Y F+R+ GQ S+LACY+G P+GVY
Sbjct 3171 VSQNGHNIRVIGHTMEGSLLKLTVDVNNPKTPAYSFIRVSTGQAMSLLACYDGLPTGVYT 3230
Query 3391 CAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVD 3450
C +R N T++ SFL GSCGS GF ++ V FCY+H +ELP G H GTD G FYGPF D
Sbjct 3231 CTLRSNGTMRASFLCGSCGSPGFVMNGKEVQFCYLHQLELPNGTHTGTDFSGVFYGPFED 3290
Query 3451 RQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHV 3510
+Q Q A D TITVNVLAWLYAAV++G+ WFL + + + +FN A+KY + +T + +
Sbjct 3291 KQVPQLAAPDCTITVNVLAWLYAAVLSGENWFLTKSSISPAEFNNCAVKYMCQSVTSESL 3350
Query 3511 DILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQS 3570
+L PL+A+TGI+V M ++LK LL G GRTI+GS LEDE TP+D+ RQ GV Q
Sbjct 3351 QVLQPLAAKTGISVERMLSALKVLLSAGFCGRTIMGSCSLEDEHTPYDIGRQMLGVKLQG 3410
Query 3571 AVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 3630
+ + T W + + ++L+L+Q QW+ L LP + F + +K
Sbjct 3411 KFQSMFRWTLQWFAIIFVLTILILLQLAQWTFVGALPFTLLLPLIGFVAVCVGFVSLLIK 3470
Query 3631 HKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 3690
HKH +L ++LLP AY+N Y P +++ + V+ D + V
Sbjct 3471 HKHTYLTVYLLPVAMVTAYYNFQYTPEGVQGYLLSLYNYVNPGRIDVIGTDLLTMLIISV 3530
Query 3691 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 3750
L++ R V D R+W + + +Y + G+A AIS ++SV +NY+GV
Sbjct 3531 ACTLLSVRMVRTDAYSRIWYVCTAVGWLYNCWTGSADTVAISYLTFMVSVFTNYTGVACA 3590
Query 3751 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 3810
++ A+ +V++ P + +C+++ Y +GY CTCYFG+F L+NR FR TLG
Sbjct 3591 SLYAAQFMVWVLKFLDPTILLLYGRFRCVLVCYLLVGYLCTCYFGVFNLINRLFRCTLGN 3650
Query 3811 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSV 3870
Y+Y+VS+QE RYMNS GLLPP NS A LNIKL G+GG P +V+T+QS M+D+KCTSV
Sbjct 3651 YEYVVSSQELRYMNSHGLLPPTNSWQALMLNIKLAGIGGIPIYRVSTIQSNMTDLKCTSV 3710
Query 3871 VLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKL 3930
VLLSVLQQLRVESSSKLWA CV+LHN+IL + TEAFE VSLLSVLLS+ GA+++++L
Sbjct 3711 VLLSVLQQLRVESSSKLWALCVKLHNEILASNSPTEAFEAFVSLLSVLLSLPGAINLDEL 3770
Query 3931 CEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSE 3990
C +L+N + LQA+ASEFS+L SY + AQ+AY+ AVA G + LKK++NVAKS
Sbjct 3771 CSSILENNSVLQAVASEFSNLSSYVDYENAQKAYDTAVATGAPASTVNALKKAMNVAKSV 3830
Query 3991 FDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIIN 4050
D+D A RKLE+M++ AMT MYKQAR+ED+R+KVT+AMQTMLF M+R+LD+DAL+NI+N
Sbjct 3831 LDKDVATTRKLERMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILN 3890
Query 4051 NARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQ 4110
NAR+G VPL +IP T A KL++V+PD++ Y T T TYA + W++ QV DAD K V
Sbjct 3891 NARNGVVPLGVIPRTAANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGKTVN 3950
Query 4111 LSEISMDNSPNLAWPLIVTALR--ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNA 4168
++I+ +NS NLAWPL+VTA R A S VKLQNNEL P +++M+ AG +QTAC D A
Sbjct 3951 ATDITRENSVNLAWPLVVTAQRQQATSPVKLQNNELMPQTVKRMNVVAGVSQTACVTD-A 4009
Query 4169 LAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL 4228
+AYYN TK GR V+A+L+D L +A+ KS G G + ELEPPC+F+ DTPKGP +KYL
Sbjct 4010 VAYYNATKEGRHVMAILADTDGLAFAKVEKSTGDGFVILELEPPCKFMVDTPKGPALKYL 4069
Query 4229 YFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGG 4288
YF KGL NL RG VLG+LA TVRL AG+ATEV +NS++LS C+F+VD YKDYL +GG
Sbjct 4070 YFTKGLKNLCRGTVLGTLACTVRLHAGSATEVASNSSILSLCSFSVDPEATYKDYLDNGG 4129
Query 4289 QPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGK 4348
PI NCVKML HTGTG AIT P+AN+DQESFGGASCCLYCRCHI+HP G C KGK
Sbjct 4130 SPIGNCVKMLTPHTGTGLAITAKPDANIDQESFGGASCCLYCRCHIEHPGASGVCKYKGK 4189
Query 4349 YVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA 4408
+VQIP NDP+GF ++N VC VC MW+GYGC C LRE LQ+ D + FLNRV G S
Sbjct 4190 FVQIPLVGVNDPIGFCIRNVVCAVCNMWQGYGCPCSSLREINLQARD-ECFLNRVRGTSG 4248
Query 4409 -ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRH 4467
ARL P G+G D+V RAFDI N KVAGF LK NCCR+QE D D +DSYFVVKRH
Sbjct 4249 VARLVPLGSGVQPDIVLRAFDICNTKVAGFGLHLKNNCCRYQELDADGTQLDSYFVVKRH 4308
Query 4468 TFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFD 4527
T SNY E+ Y LKDC VA+HDFFKF I+G M PH+SR+RLTKYTMADLVY+LRHFD
Sbjct 4309 TESNYLLEQRCYEKLKDCGVVARHDFFKFNIEGVMTPHVSRERLTKYTMADLVYSLRHFD 4368
Query 4528 EGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDA 4587
NCDTLKEILV CC DYF++KDWYD VENPDI+RVY NLGE VR+A+L V+ D+
Sbjct 4369 NNNCDTLKEILVLRGCCTADYFDRKDWYDPVENPDIIRVYHNLGETVRKAVLSAVKMADS 4428
Query 4588 MRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAES 4647
M G++GVLTLDNQDLNG WYDFGDFI+ G+GV V+D+YYSL MP+ T+T L AE
Sbjct 4429 MVEQGLIGVLTLDNQDLNGQWYDFGDFIEGPAGAGVAVMDTYYSLAMPVYTMTNMLAAEC 4488
Query 4648 HVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNV 4707
HVD D +KP WD+ KYD+T+ + LF +YFKYWD YHPNCV C DDRCILHCANFN+
Sbjct 4489 HVDGDFSKPKRVWDICKYDYTQFKYSLFSKYFKYWDMQYHPNCVACADDRCILHCANFNI 4548
Query 4708 LFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYA 4767
LFS V P TSFGPLV+KI+VDGVPFVVSTGYH+RELGVV NQD+ H+ RLS +ELLVYA
Sbjct 4549 LFSMVLPNTSFGPLVQKIYVDGVPFVVSTGYHYRELGVVMNQDIRQHAQRLSLRELLVYA 4608
Query 4768 ADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSV 4827
ADPAMH A+ N L DKRT C SVAA+T V FQTVKPG FN+DFY+FAV GFFKEGS++
Sbjct 4609 ADPAMHVAASNALADKRTVCMSVAAMTTGVTFQTVKPGQFNEDFYNFAVKCGFFKEGSTI 4668
Query 4828 ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIV 4887
KHFF+AQDGNAAISDYDYYRYNLPTMCDI+QLLF +EVVDKYFDCYDGGC+ A+QV+V
Sbjct 4669 SFKHFFYAQDGNAAISDYDYYRYNLPTMCDIKQLLFSLEVVDKYFDCYDGGCLQASQVVV 4728
Query 4888 NNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRAR 4947
N DKSAGFPFNK+GKARLYY+S+SY DQD LFAYTKRNV+PTITQMNLKYAISAKNRAR
Sbjct 4729 ANYDKSAGFPFNKFGKARLYYESLSYADQDELFAYTKRNVLPTITQMNLKYAISAKNRAR 4788
Query 4948 TVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLM 5007
TVAGVSI STMTNRQFHQK+LKSIAA RGA+VVIGT+KFYGGW+ ML+T+ VENPHLM
Sbjct 4789 TVAGVSIASTMTNRQFHQKMLKSIAAARGASVVIGTTKFYGGWNRMLRTLCEGVENPHLM 4848
Query 5008 GWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYV 5067
GWDYPKCDRAMPN+LRI ASL+LARKH TCC+ S RFYRLANECAQVLSEMV+CGG YV
Sbjct 4849 GWDYPKCDRAMPNLLRIFASLILARKHATCCNASERFYRLANECAQVLSEMVLCGGGFYV 4908
Query 5068 KPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNR 5127
KPGGTSSGD+TTAYANSVFNICQAV+AN+N LS DGNKI YV+ LQ RLY +YR+
Sbjct 4909 KPGGTSSGDSTTAYANSVFNICQAVSANLNTFLSIDGNKIYTTYVQELQRRLYLGIYRSN 4968
Query 5128 DVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMS 5187
VD + V ++Y YLRKHFSMMILSDD VVC+N+ YA +G VA I+ FK +LY+QNNVFMS
Sbjct 4969 TVDNELVLDYYNYLRKHFSMMILSDDGVVCYNADYAQKGYVADIQGFKELLYFQNNVFMS 5028
Query 5188 EAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLM 5247
E+KCW E D+TKGPHEFCSQHTMLV + VYLPYPDPSRILGAGCFVDD++KTDGTLM
Sbjct 5029 ESKCWVEPDITKGPHEFCSQHTMLVDMKGEQVYLPYPDPSRILGAGCFVDDLLKTDGTLM 5088
Query 5248 IERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRY 5307
+ER+VSLAIDAYPLTKHP+ EY +VF YLQYI+KLH+ELTGH+LD YSVML +DN S+Y
Sbjct 5089 MERYVSLAIDAYPLTKHPDPEYQNVFWCYLQYIKKLHEELTGHLLDTYSVMLASDNASKY 5148
Query 5308 WEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVL 5367
WE EFYE MY LQ+VG CV+CNSQTSLRCG CIRRPFLCCKCCYDHV+ST+HKLVL
Sbjct 5149 WEVEFYENMYMESATLQSVGTCVVCNSQTSLRCGGCIRRPFLCCKCCYDHVVSTTHKLVL 5208
Query 5368 SVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNV 5427
SV PYVCN P CDV DVTQLYLGGMSYYC+ H+PPISFPLCANGQVFGLYKN C GS +V
Sbjct 5209 SVTPYVCNNPSCDVADVTQLYLGGMSYYCRDHRPPISFPLCANGQVFGLYKNICTGSPDV 5268
Query 5428 TDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDREL 5487
DFN++ATCDW+N+ DY+LANT TERLKLFAAETL+ATEE K +Y A V+EVLSDREL
Sbjct 5269 ADFNSLATCDWSNSKDYVLANTATERLKLFAAETLRATEENAKQAYASAVVKEVLSDREL 5328
Query 5488 HLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGD 5547
LSWE GK RPPLNRNYVFTG+ +TKNSKVQ+GEY FEKGDYGD V YR +TTYKL VGD
Sbjct 5329 VLSWETGKTRPPLNRNYVFTGFHITKNSKVQLGEYIFEKGDYGDVVNYRSSTTYKLQVGD 5388
Query 5548 YFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGP 5607
YFVLTSH+V PLS+PTL+PQE Y ++ GLYP +N+ + F+SNV +YQ+VGM +Y+T+QGP
Sbjct 5389 YFVLTSHSVQPLSSPTLLPQERYTKLVGLYPAMNVPESFASNVVHYQRVGMSRYTTVQGP 5448
Query 5608 PGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECF 5667
PGTGKSH +IGLALYYPSA+IVYTACSHAAVDALCEKA K LPI++CSRI+PA+ARVECF
Sbjct 5449 PGTGKSHLSIGLALYYPSAKIVYTACSHAAVDALCEKAHKNLPINRCSRIVPAKARVECF 5508
Query 5668 DKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPA 5727
KFKVN QYVF T+NALPETTADI+V DE+SM TNYDLS++NAR+RAKH VY+GDPA
Sbjct 5509 SKFKVNDVGAQYVFSTINALPETTADILVVDEVSMCTNYDLSMINARVRAKHIVYVGDPA 5568
Query 5728 QLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKA 5787
QLPAPRTLLTKGTL PE+FNSVCRLM +GPD+FL TC RCP EIVDTVSALVYD KLKA
Sbjct 5569 QLPAPRTLLTKGTLAPEHFNSVCRLMVAVGPDIFLATCYRCPKEIVDTVSALVYDKKLKA 5628
Query 5788 HKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVAS 5847
+K + +C+K +YKG +THD SSAIN+PQ+G+V+EFL +NP W+ AVFISPYNSQN+VA
Sbjct 5629 NKVTTGECYKCYYKGSVTHDSSSAINKPQLGLVKEFLIKNPKWQSAVFISPYNSQNSVAR 5688
Query 5848 KILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYD 5907
++LGL TQTVDSSQGSE+DYVI+ QT++TAH+ NVNRFNVAITRAK GILC+MSD LY+
Sbjct 5689 RMLGLQTQTVDSSQGSEFDYVIYCQTSDTAHALNVNRFNVAITRAKKGILCVMSDSTLYE 5748
Query 5908 KLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVD 5966
L+FT L++ +Q+E GLFKDC+K L P APT +SV+ KFK E LCV
Sbjct 5749 SLEFTPLDVNDYVKPKMQSEVTVGLFKDCAKA-EPLGPAYAPTFVSVNDKFKLNESLCVH 5807
Query 5967 IPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAV 6026
M Y RLIS MGFK + + GY +FITRE+AIR VR W+GFDVEG HA +
Sbjct 5808 FDTTELQMPYNRLISKMGFKFDLNIPGYSKLFITREQAIREVRGWVGFDVEGAHACGPNI 5867
Query 6027 GTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNV 6086
GTNLPLQ+GFSTGVN V P+GY+DT + + + V +K PPGDQFKHLIPLM KG PW+V
Sbjct 5868 GTNLPLQIGFSTGVNFVVTPSGYIDTESGSRLANVVSKAPPGDQFKHLIPLMRKGEPWSV 5927
Query 6087 VRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTAS 6146
VR +IV+ML DTL +SD V FV WAHGFELT++ YF K+GPER C +C RRAT FS+
Sbjct 5928 VRKRIVEMLCDTLDGVSDTVTFVTWAHGFELTTLHYFAKVGPERKCFMCPRRATLFSSVY 5987
Query 6147 DTYACWHHSI---GFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTR 6203
Y+CW H G D+VYNPF++DVQQWG+ GNLQ NHD C VH AHVASCDAIMTR
Sbjct 5988 GAYSCWSHHRHIGGADFVYNPFLVDVQQWGYVGNLQVNHDNVCDVHKGAHVASCDAIMTR 6047
Query 6204 CLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAI 6263
CLA+H+CF V+W +EYPII +EL IN ACR VQ +V+KAA+ A ++DIGNPKAI
Sbjct 6048 CLAIHDCFCGEVNWDVEYPIIANELAINRACRSVQRVVLKAAVKALHIETIYDIGNPKAI 6107
Query 6264 KCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIV 6323
K W FYD P + +++L Y Y H D+F DG+ +FWNCNVD YP N++V
Sbjct 6108 KVYGVNVNNWNFYDTNPVVE---GVKQLHYVYDVHRDQFKDGLAMFWNCNVDCYPHNALV 6164
Query 6324 CRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESH--- 6380
CRFDTRVLS LNL GC+GGSLYVN+HAFHT AF+K+AFVNLK LPFFYYSD+ CE+
Sbjct 6165 CRFDTRVLSKLNLAGCNGGSLYVNQHAFHTDAFNKNAFVNLKPLPFFYYSDTACENATGV 6224
Query 6381 GKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFD 6440
VS++DYVPLKS CITRCNLGGAVC+ HA+EYR +L++YN M+SAGF+LWV K FD
Sbjct 6225 STNYVSEVDYVPLKSNVCITRCNLGGAVCKKHADEYRNFLESYNTMVSAGFTLWVDKTFD 6284
Query 6441 TYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTT 6500
+NLW+TF +LQSLENVA+NV+ GHF GE+PV+I+N+ +Y K DG D LF N T
Sbjct 6285 VFNLWSTFVKLQSLENVAYNVLKSGHFTAVAGELPVAILNDRLYIKEDGADKLLFTNNTC 6344
Query 6501 LPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIA 6560
LP NVAFELWAKR++ VPEVK+L NLGV N VIWDY+ +AP +T+G+C+ TD+
Sbjct 6345 LPTNVAFELWAKRSVNVVPEVKLLRNLGVTCTYNLVIWDYESNAPLVPNTVGICTYTDLT 6404
Query 6561 KKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI 6620
K + V DGR F +N + + K + + GP AS+NGV +
Sbjct 6405 KLDDQ------VVLVDGRQLDAYSKFCQLKNAIYFSPSKPKCVC-TRGPTHASINGVVVE 6457
Query 6621 GEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLE 6680
T F Y + DG Q + YFTQSR + +F+PR+Q+EIDFL+L F+++Y L
Sbjct 6458 APDRGTAFWYAMRKDGAFVQPTDGYFTQSRTVDDFQPRTQLEIDFLDLEQSCFLDKYDLH 6517
Query 6681 GYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSS 6740
EHIVYG F + +GGLHLLIG +R + + +E + D TV +Y + D T SS
Sbjct 6518 DLGLEHIVYGQFDGT-IGGLHLLIGAVRRKRTAHLVMETVLGTD-TVTSYAVIDQPTASS 6575
Query 6741 KCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSS 6800
K VCSV+D++LDDF+ +IK+QD SVVSKVV+ +D+ FMLWCK G + TFYP+LQ+
Sbjct 6576 KQVCSVVDIILDDFIALIKAQDRSVVSKVVQCCLDFKVFRFMLWCKGGKISTFYPQLQAK 6635
Query 6801 QAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVP 6860
Q W+PG +MP LYK+Q +LE C L NYG +A LP G +MNVAKYTQLCQYLNT +LAVP
Sbjct 6636 QDWKPGYSMPALYKVQNAVLEPCLLHNYGQAARLPSGTLMNVAKYTQLCQYLNTCSLAVP 6695
Query 6861 YNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTAN 6920
MRV+HFGAGSDKGV PGTAVL+QWLP LVD+DL SDADST +G C T + N
Sbjct 6696 AKMRVMHFGAGSDKGVCPGTAVLKQWLPADAYLVDNDLCYCASDADSTYVGSCETFFSVN 6755
Query 6921 KWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYK 6980
KWD I SDMYD +TKN + +N SKEGFFTY+ GFI+ KLALGGS+AIKITEHSW+ADLY
Sbjct 6756 KWDFIFSDMYDARTKNTSGDNTSKEGFFTYLTGFIRSKLALGGSIAIKITEHSWSADLYA 6815
Query 6981 LMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSY 7040
+MGHF WWT F T+VN+SSSEAFLIG NY+G +DG+ MHANY+FWRN+ +QLSSY
Sbjct 6816 IMGHFNWWTCFCTSVNSSSSEAFLIGVNYIGV-GALLDGWQMHANYVFWRNSTVMQLSSY 6874
Query 7041 SLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRE 7082
SL+D+ +FPL+L+GT VMSLKE Q+N+++L+L+ GRLI+R+
Sbjct 6875 SLYDLQRFPLRLKGTPVMSLKEDQLNELVLNLIRAGRLIVRD 6916
>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=rep PE=1 SV=1
Length=7078
Score = 5991 bits (15542), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3040/5978 (51%), Positives = 3999/5978 (67%), Gaps = 202/5978 (3%)
Query 1259 INGNLHPDSATLVSDIDITFLKKDAPYIVGD-VVQEGVLTA-----VVIPTKKAGGTTEM 1312
I G ++ S V ++ P VGD V+ +G A VV P +A +
Sbjct 1156 IAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSL 1215
Query 1313 LAK---ALRKVPTDNYITTYPGQGLNG--------YTVEEAKTVLKKCKSAFYILPSIIS 1361
L+K A+ P +T G+ G Y + EAKT + ++ + S+
Sbjct 1216 LSKCYKAMNAYPL--VVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTI 1273
Query 1362 NEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGAR 1421
+ + L LR + A++ + VC + A ++ K + VD G +
Sbjct 1274 VDIPQSLTFSYDGLRGAIRKAKDYGFTVFVCTDNSANTKVLRNKGVDYTKKFLTVD-GVQ 1332
Query 1422 FYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPD 1481
+Y YTSK T+ ++ N + +++MPLGYV+HGL+L +A +R + VP +++ +
Sbjct 1333 YYCYTSKDTLDDILQQANK-SVGIISMPLGYVSHGLDLIQAGSVVRRVNVPYVCLLANKE 1391
Query 1482 AVTAYNGYLTSSSK--TPEEHFIETISLAGSYKDWSYSG-----QSTQLGIEFLKRGDKS 1534
L S P E FI+ + G Y W Q +L + L D++
Sbjct 1392 Q----EAILMSEDVKLNPSEDFIKHVRTNGGYNSWHLVEGELLVQDLRLN-KLLHWSDQT 1446
Query 1535 VYYTSNPTTFHLDGEVITFDNLKTLLSLREVRT-----IKVFTTVDNINLHTQVVDMSMT 1589
+ Y + + F+ L + + RT I+V TVD +N T V++ T
Sbjct 1447 ICYKDSVFYVVKNSTAFPFETLSACRAYLDSRTTQQLTIEVLVTVDGVNFRTVVLNNKNT 1506
Query 1590 YGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAF-EYYHTTDPSFLGRYMS 1648
Y Q G + +GAD++ P G + Y+ N +A E Y DP+FL R+ S
Sbjct 1507 YRSQLGCVFFNGADISDTIPDEKQNGHSLYLADNLTADETKALKELYGPVDPTFLHRFYS 1566
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQI-ELKFNPPALQDAYYRARAGEA 1707
KWK + + S+K +DNNCYL ++TL + ++KF PALQ A+ + + G++
Sbjct 1567 LKAAVHKWKMVVCDKVRSLKLSDNNCYLNAVIMTLDLLKDIKFVIPALQHAFMKHKGGDS 1626
Query 1708 ANFCALILAYCNKTVGELGDVRETMSYLFQHANLD-SCKRVLNVVCKTCGQQQTTLKGVE 1766
+F ALI+AY N T G D + + A L S + V C CG + L+G++
Sbjct 1627 TDFIALIMAYGNCTFGAPDDASRLLHTVLAKAELCCSARMVWREWCNVCGIKDVVLQGLK 1686
Query 1767 AVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGT---FTC 1823
A Y+G + E + + C CG + + +V+ +P++++S P + + T F
Sbjct 1687 ACCYVGVQTVEDLRARMTYVCQCGGERHRQIVEHTTPWLLLSGTPNEKLVTTSTAPDFVA 1746
Query 1824 ASEYTG-NYQCGHYKHITSKETLYC-IDGALLTKSSEYKGPITDVFYKENSYTTTIKPVT 1881
+ + G GHY H K L D ++K+S++K +TDV + Y++ V
Sbjct 1747 FNVFQGIETAVGHYVHARLKGGLILKFDSGTVSKTSDWKCKVTDVLFPGQKYSSDCNVVR 1806
Query 1882 YKLDGVVCTEIDPKLDNYYKKDNSYFT-EQPIDLVPNQPYPNASFDNFKFVCDNIKFADD 1940
Y LDG TE+DP L +Y KD YFT E P+ P + + N V + + D
Sbjct 1807 YSLDGNFRTEVDPDLSAFYVKDGKYFTSEPPVTYSPATILAGSVYTNSCLVSSDGQPGGD 1866
Query 1941 -----LNQLTGY--KKPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWH 1993
N L G+ KP +++ +F P +GDV+ ++ Y P +K GA KPI+W
Sbjct 1867 AISLSFNNLLGFDSSKPVTKKYTYSFLPKEDGDVLLAEFDTYDPIYKNGAMYKGKPILW- 1925
Query 1994 VNNATNKATY-----KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVS 2048
NKA+Y K N +R ++ P+E N F L E PV
Sbjct 1926 ----VNKASYDTNLNKFNRASLRQIFDVAPIELENKFTPLSVEST------------PVE 1969
Query 2049 EEVVENPTIQKD--VLECNVKTTEVVGDIILKPANNS-LKITEEVGHTDLMAAYVD-NSS 2104
V+ +Q++ +++C V D + A++S + E + DL YVD
Sbjct 1970 PPTVDVVALQQEMTIVKCKGLNKPFVKDNVSFVADDSGTPVVEYLSKEDLHTLYVDPKYQ 2029
Query 2105 LTIKKPNELSRVLGLKTLATHGL---AAVNSVPWDTIANYAKPFLNK----VVSTTTNIV 2157
+ + K N LS +L L T+ + + AA S+ + F K T T V
Sbjct 2030 VIVLKDNVLSSMLRLHTVESGDINVVAASGSLTRKVKLLFRASFYFKEFATRTFTATTAV 2089
Query 2158 TRCLNRV-------------CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTT---IAKN 2201
C+ V C +++ F L L + ++ + +K S T + N
Sbjct 2090 GSCIKSVVRHLGVTKGILTGCFSFVKMLFMLPLAYFSDSKLGTTEVKVSALKTAGVVTGN 2149
Query 2202 TVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSN----- 2256
VK ++ S + L+ ++ + +++ V L S+ + VL S+
Sbjct 2150 VVKQCCTAAVDLSMDKLRRVDWKSTLRLLLMLCTTMVLLSSVYHLYVFNQVLSSDVMFED 2209
Query 2257 --------------LGMPSYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDSLDTY 2301
LG+ S C G Y + + + T+C S C+ CL DS+ Y
Sbjct 2210 AQGLKKFYKEVRAYLGISSACDGLASAY-RANSFDVPTFCANRSAMCNWCLISQDSITHY 2268
Query 2302 PSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISN 2361
P+L+ +Q +S + ++ E LAY+L+T F L LA + FF+ ++
Sbjct 2269 PALKMVQTHLSHYVLNIDWLWFAFETGLAYMLYTSAFNWLLLAGTLHYFFAQTSIFVDWR 2328
Query 2362 SW------LMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKR 2415
S+ WL ++ P++ +VRMY A + + K Y HV++GC + C++CYKR
Sbjct 2329 SYNYAVSSAFWLFTHI----PMAGLVRMYNLLACLWLLRKFYQHVINGCKDTACLLCYKR 2384
Query 2416 NRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSL 2475
NR TRVE +T+V G +R+FY+ ANGG FC+ HNWNCV+CDT G+TFI +EVA DL+
Sbjct 2385 NRLTRVEASTVVCGGKRTFYITANGGISFCRRHNWNCVDCDTAGVGNTFICEEVANDLTT 2444
Query 2476 QFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLR----ANN 2531
+RPIN TD+S Y VDSVTVK + + + GQ YER L F NLD L+
Sbjct 2445 ALRRPINATDRSHYYVDSVTVKETVVQFNYRRDGQPFYERFPLCAFTNLDKLKFKEVCKT 2504
Query 2532 TKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMF 2591
T G N I++D + +ES A+SA VYYSQ++C+ ILL+D +LV+ VGDS+E+A KMF
Sbjct 2505 TTGIPEYNFIIYDSSDRGQESLARSACVYYSQVLCKSILLVDSSLVTSVGDSSEIATKMF 2564
Query 2592 DAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDVETKD 2650
D++VN+F S +NV +KL+ L++TA + + + +VL+TFI AAR V+SDVET +
Sbjct 2565 DSFVNSFVSLYNVTRDKLEKLISTARDGVRRGDNFHSVLTTFIDAARGPAGVESDVETNE 2624
Query 2651 VVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIA 2710
+V+ ++ +H+ DI++T +S NNY+ +Y K ++++ DLG+ IDC+A +N V ++ N A
Sbjct 2625 IVDSVQYAHKHDIQITNESYNNYVPSYVKPDSVSTSDLGSLIDCNAASVNQIVLRNSNGA 2684
Query 2711 LIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNN-- 2768
IWN +M LS+ L++QIR A +K NL F+LT + R N+++ + KIV
Sbjct 2685 CIWNAAAYMKLSDALKRQIRIACRKCNLAFRLTTSKLRANDNILSVR--FTANKIVGGAP 2742
Query 2769 -W--------LKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRD 2819
W LK + T++ A + YL P M + I+ +K +D G+ RD
Sbjct 2743 TWFNALRDFTLKGYVLATIIVFLCAVLMYLCLPTFSMVPVEFYEDRILDFKVLDNGIIRD 2802
Query 2820 IASTDTCFANKHADFDTWFSQR-GGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTN 2878
+ D CFANKH F W+ + GG Y N CPL AVI G +P +P T L N
Sbjct 2803 VNPDDKCFANKHRSFTQWYHEHVGGVYDNSITCPLTVAVIAGVAGARIPDVP-TTLAWVN 2861
Query 2879 GDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNV 2938
+ F+ RVF+ G++CYTP I Y F+ S C+L +ECT+F+DA G+ PYC+D V
Sbjct 2862 NQIIFFVSRVFANTGSVCYTPIDEIPYKSFSDSGCILPSECTMFRDAEGRMTPYCHDPTV 2921
Query 2939 LEGSVAYESLRPDTRYVLMDGSI-IQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVC 2997
L G+ AY +RP RY L DG++ I+FP E ++R+ T ++YCR G+CE ++ GVC
Sbjct 2922 LPGAFAYSQMRPHVRYDLYDGNMFIKFPEVVFESTLRITRTLSTQYCRFGSCEYAQEGVC 2981
Query 2998 VSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVV 3057
++T+G W + ND++ + PGV+CG D ++++ + L QPI ++ S+V G + +
Sbjct 2982 ITTNGSWAIFNDHHLNRPGVYCGSDFIDIVRRLAVSLFQPITYFQLTTSLVLGIGLCAFL 3041
Query 3058 TCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLT 3117
T L YY + +RAF +Y+ + +++ +C Y+ +Y Y TFY T
Sbjct 3042 TLLFYYINKVKRAFADYTQCAVIAVVAAVLNSLCICFVASIPLCIVPYTALYYYATFYFT 3101
Query 3118 NDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV-VF-NGVSFSTF 3175
N+ +F+ H+ W +MF P+VP W+T Y + + +HF+W + + K+ V VF +G +F
Sbjct 3102 NEPAFIMHVSWYIMFGPIVPIWMTCVYTVAMCFRHFFWVLAYFSKKHVEVFTDGKLNCSF 3161
Query 3176 EEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLA 3235
++AA F++NK+ Y LR+ L Y+R+L L+NKYKYFSGAM+T +YREAA CHLA
Sbjct 3162 QDAASNIFVINKDTYAALRNS--LTNDAYSRFLGLFNKYKYFSGAMETAAYREAAACHLA 3219
Query 3236 KALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
KAL +S +GSD+LYQPP SITS VLQSG KM+ PSG VE CMVQVTCG+ TLNGLWL
Sbjct 3220 KALQTYSETGSDLLYQPPNCSITSGVLQSGLVKMSHPSGDVEACMVQVTCGSMTLNGLWL 3279
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQ---AGNVQLRVIGHSMQNCVLKL 3352
D+ V+CPRHV+C ++ + +PNY+ LLI +NH+F VQ LRV+GH+MQ +LKL
Sbjct 3280 DNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVVGHAMQGTLLKL 3339
Query 3353 KVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVG 3412
VD ANP TP Y F ++PG FSVLACYNG P+G + MRPN+TIKGSFL GSCGSVG
Sbjct 3340 TVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCGSCGSVG 3399
Query 3413 FNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLY 3472
+ + ++FCYMH MEL G H G+ +G YG F+D+Q Q TD +VNV+AWLY
Sbjct 3400 YTKEGSVINFCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLY 3459
Query 3473 AAVINGDRWFLNRFTTTLNDFNLVAMKYNY-EPLTQDHVDILGPLSAQTGIAVLDMCASL 3531
AA++NG WF+ T++ FN A+ + E + VD+L + +TG+A+ + ++
Sbjct 3460 AAILNGCAWFVKPNRTSVVSFNEWALANQFTEFVGTQSVDML---AVKTGVAIEQLLYAI 3516
Query 3532 KELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSL 3591
++L G G+ ILGS +LEDEFTP DV Q GV QS V++ GT HWL T++++
Sbjct 3517 QQLY-TGFQGKQILGSTMLEDEFTPEDVNMQIMGVVMQSGVRKVTYGTAHWLFATLVSTY 3575
Query 3592 LVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN 3651
++++Q+T+++L+ +L+E + AF M+ VKHKH FL LFLLP + Y N
Sbjct 3576 VIILQATKFTLWNYLFETIPTQLFPLLFVTMAFVMLLVKHKHTFLTLFLLPVAICLTYAN 3635
Query 3652 MVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARR 3707
+VY P +S ++ + WL + + D +Y S ++L+++ R +
Sbjct 3636 IVYEPTTPISSALIAVANWLAPTNAYMRTTH-TDIGVYISMSLVLVIVVKRLYNPSLSNF 3694
Query 3708 VWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCP 3767
L + + +Y G A I+ + ++TS+Y+ V + LA+ + Y P
Sbjct 3695 ALALCSGVMWLYTYSIGEA-SSPIAYLVFVTTLTSDYTITVFVTVNLAKVCTYAIFAYSP 3753
Query 3768 IFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQG 3827
+ ++ I+L+Y LG+ CTCYFG+F LLN R +GVYD+ VSTQEFR+M +
Sbjct 3754 QLTLVFPEVKMILLLYTCLGFMCTCYFGVFSLLNLKLRAPMGVYDFKVSTQEFRFMTANN 3813
Query 3828 LLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKL 3887
L P+NS +A LN KL+G+GG PCIKVA +QSK++D+KCTSVVLLSVLQQL +E++S+
Sbjct 3814 LTAPRNSWEAMALNFKLIGIGGTPCIKVAAMQSKLTDLKCTSVVLLSVLQQLHLEANSRA 3873
Query 3888 WAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASE 3947
WA CV+ HNDIL A D +EAFEK VSL + L++ G VD++ L ++ D + LQA SE
Sbjct 3874 WAFCVKCHNDILAATDPSEAFEKFVSLFATLMTFSGNVDLDALASDIFDTPSVLQATLSE 3933
Query 3948 FSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMAD 4006
FS L ++A AQ+AY++A+ +GD S VLK L+K++N+AK+ +++D A+ RKLE+MAD
Sbjct 3934 FSHLATFAELEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKNAYEKDKAVARKLERMAD 3993
Query 4007 QAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTT 4066
QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN II+NAR+GC+PL++IPL
Sbjct 3994 QAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIPLSVIPLCA 4053
Query 4067 AAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPL 4126
+ KL VVIPD+ + + YA ALW+I + + D++IV+ S++ +D++ NL WPL
Sbjct 4054 SNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDV-VDSNENLTWPL 4112
Query 4127 IVTALRAN-SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALL 4185
++ RA+ SAVKLQNNE+ P L+ M +AG QT C + ++LAYY +G + ++ALL
Sbjct 4113 VLECTRASTSAVKLQNNEIKPSGLKTMVVSAGQEQTNC-NTSSLAYYEPVQGRKMLMALL 4171
Query 4186 SDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGS 4245
SD LKWAR DG ++ EL+PPC+F+ PKGP+++YLYF+K LNNL+RG VLG
Sbjct 4172 SDNAYLKWARVEGKDGFVSV--ELQPPCKFLIAGPKGPEIRYLYFVKNLNNLHRGQVLGH 4229
Query 4246 LAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTG 4305
+AATVRLQAG+ TE +NS+VLS F VD KAY D++ +GG P+TNCVKML TGTG
Sbjct 4230 IAATVRLQAGSNTEFASNSSVLSLVNFTVDPQKAYLDFVNAGGAPLTNCVKMLTPKTGTG 4289
Query 4306 QAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL 4365
AI+V PE+ DQE++GGAS CLYCR HI+HP+ G C KGK+VQIP C DPVGF L
Sbjct 4290 IAISVKPESTADQETYGGASVCLYCRAHIEHPDVSGVCKYKGKFVQIPAQCVRDPVGFCL 4349
Query 4366 KNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCG-VSAARLTPCGTGTSTDVVY 4424
NT C VC W GYGC+CD LR+ L + +FL RV G + AR+ PC +G STDVV+
Sbjct 4350 SNTPCNVCQYWIGYGCNCDSLRQAALPQSKDSNFLKRVRGSIVNARIEPCSSGLSTDVVF 4409
Query 4425 RAFDI--YNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLL 4482
RAFDI Y KVAG K+ KTN CRF E D+ + +DSYFVVKRHT NY+ E+ Y+LL
Sbjct 4410 RAFDICNYKAKVAGIGKYYKTNTCRFVELDDQGHHLDSYFVVKRHTMENYELEKHCYDLL 4469
Query 4483 KDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYN 4542
+DC AVA HDFF F +D PHI RQRLT+YTM DLVYALRHFD+ N + LK ILV Y
Sbjct 4470 RDCDAVAPHDFFIFDVDKVKTPHIVRQRLTEYTMMDLVYALRHFDQ-NSEVLKAILVKYG 4528
Query 4543 CCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQ 4602
CCD YF K W+DFVENP ++ VY LGERVRQA+L TV+FCD M AG+VGVLTLDNQ
Sbjct 4529 CCDVTYFENKLWFDFVENPSVIGVYHKLGERVRQAILNTVKFCDHMVKAGLVGVLTLDNQ 4588
Query 4603 DLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDL 4662
DLNG WYDFGDF+ T PGSGV +VDSYYS LMP+L++T L AE+H D D KP I+W L
Sbjct 4589 DLNGKWYDFGDFVITQPGSGVAIVDSYYSYLMPVLSMTDCLAAETHRDCDFNKPLIEWPL 4648
Query 4663 LKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLV 4722
+YDFT+ +++LF++YFKYWDQTYH NCVNC DDRC+LHCANFNVLF+ P T FGP+V
Sbjct 4649 TEYDFTDYKVQLFEKYFKYWDQTYHANCVNCTDDRCVLHCANFNVLFAMTMPKTCFGPIV 4708
Query 4723 RKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLD 4782
RKIFVDGVPFVVS GYH++ELG+V N DV+LH RLS KEL++YAADPAMH AS N LD
Sbjct 4709 RKIFVDGVPFVVSCGYHYKELGLVMNMDVSLHRHRLSLKELMMYAADPAMHIASSNAFLD 4768
Query 4783 KRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAI 4842
RT+CFSVAALT + FQTV+PGNFN+DFYDF VSKGFFKEGSSV LKHFFFAQDGNAAI
Sbjct 4769 LRTSCFSVAALTTGLTFQTVRPGNFNQDFYDFVVSKGFFKEGSSVTLKHFFFAQDGNAAI 4828
Query 4843 SDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWG 4902
+DY+YY YNLPTMCDI+Q+LF +EVV+KYF+ YDGGC+NA++V+VNNLDKSAG PFNK+G
Sbjct 4829 TDYNYYSYNLPTMCDIKQMLFCMEVVNKYFEIYDGGCLNASEVVVNNLDKSAGHPFNKFG 4888
Query 4903 KARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQ 4962
KAR+YY+SMSY++QD LFA TKRNVIPT+TQMNLKYAISAKNRARTVAGVSI STMTNRQ
Sbjct 4889 KARVYYESMSYQEQDELFAMTKRNVIPTMTQMNLKYAISAKNRARTVAGVSILSTMTNRQ 4948
Query 4963 FHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNML 5022
+HQK+LKS+AATRGAT VIGT+KFYGGW MLKT+Y DV+NPHLMGWDYPKCDRAMPNM
Sbjct 4949 YHQKMLKSMAATRGATCVIGTTKFYGGWDFMLKTLYKDVDNPHLMGWDYPKCDRAMPNMC 5008
Query 5023 RIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYA 5082
RI ASL+LARKH TCC+ RFYRLANECAQVLSE V+CGG YVKPGGTSSGDATTAYA
Sbjct 5009 RIFASLILARKHGTCCTTRDRFYRLANECAQVLSEYVLCGGGYYVKPGGTSSGDATTAYA 5068
Query 5083 NSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLR 5142
NSVFNI QA TANV+AL+ +GNKI DK V+++Q LY +YR+ D FV+++YA+L
Sbjct 5069 NSVFNILQATTANVSALMGANGNKIVDKEVKDMQFDLYVNVYRSTSPDPKFVDKYYAFLN 5128
Query 5143 KHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPH 5202
KHFSMMILSDD VVC+NS YA++G +A I+NFK LYYQNNVFMSEAKCW ETDL KGPH
Sbjct 5129 KHFSMMILSDDGVVCYNSDYAAKGYIAGIQNFKETLYYQNNVFMSEAKCWVETDLKKGPH 5188
Query 5203 EFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLT 5262
EFCSQHT+ +K GDD +LPYPDPSRIL AGCFVDDIVKTDGTLM+ERFVSLAIDAYPLT
Sbjct 5189 EFCSQHTLYIKDGDDGYFLPYPDPSRILSAGCFVDDIVKTDGTLMVERFVSLAIDAYPLT 5248
Query 5263 KHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTV 5322
KH + EY +VF +YLQYI KL+ +LTGHMLD YSVML DN++++WE FY +Y+ T
Sbjct 5249 KHEDIEYQNVFWVYLQYIEKLYKDLTGHMLDSYSVMLCGDNSAKFWEEAFYRDLYSSPTT 5308
Query 5323 LQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVT 5382
LQAVG+CV+C+SQTSLRCG CIRRPFLCCKCCYDHVI+T HK+VLSV+PYVCNAPGC V+
Sbjct 5309 LQAVGSCVVCHSQTSLRCGTCIRRPFLCCKCCYDHVIATPHKMVLSVSPYVCNAPGCGVS 5368
Query 5383 DVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAG 5442
DVT+LYLGGMSY+C H+P SFPLCANG VFGLYKN C GS ++ +FN +ATCDWT +G
Sbjct 5369 DVTKLYLGGMSYFCVDHRPVCSFPLCANGLVFGLYKNMCTGSPSIVEFNRLATCDWTESG 5428
Query 5443 DYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNR 5502
DY LANT TE LKLFAAETL+ATEE K SY IAT++E++ +R+L L WE GK +PPLNR
Sbjct 5429 DYTLANTTTEPLKLFAAETLRATEEASKQSYAIATIKEIVGERQLLLVWEAGKSKPPLNR 5488
Query 5503 NYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAP 5562
NYVFTGY +TKNSKVQ+GEY FE+ DY DAV Y+ +TTYKL VGD FVLTSH+V L+AP
Sbjct 5489 NYVFTGYHITKNSKVQLGEYIFERIDYSDAVSYKSSTTYKLTVGDIFVLTSHSVATLTAP 5548
Query 5563 TLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALY 5622
T+V QE YV+ITGLYPT+ + +EF+S+VAN+QK G KY T+QGPPGTGKSHFAIGLA+Y
Sbjct 5549 TIVNQERYVKITGLYPTITVPEEFASHVANFQKSGYSKYVTVQGPPGTGKSHFAIGLAIY 5608
Query 5623 YPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFC 5682
YP+AR+VYTACSHAAVDALCEKA KYL I KCSRIIPA+ARVEC+D+FKVN T QY+F
Sbjct 5609 YPTARVVYTACSHAAVDALCEKAFKYLNIAKCSRIIPAKARVECYDRFKVNETNSQYLFS 5668
Query 5683 TVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLE 5742
T+NALPET+ADI+V DE+SM TNYDLS++NAR++AKH VY+GDPAQLPAPRTLLT+GTLE
Sbjct 5669 TINALPETSADILVVDEVSMCTNYDLSIINARIKAKHIVYVGDPAQLPAPRTLLTRGTLE 5728
Query 5743 PEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKG 5802
PE FNSV RLM +GPD+FL C RCP EIV TVSALVY+NKL A K+ S QCFK+ YKG
Sbjct 5729 PENFNSVTRLMCNLGPDIFLSMCYRCPKEIVSTVSALVYNNKLLAKKELSGQCFKILYKG 5788
Query 5803 VITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQG 5862
+THD SSAINRPQ+ V+ F+T NPAW KAVFISPYNSQNAVA +LGL TQTVDSSQG
Sbjct 5789 NVTHDASSAINRPQLTFVKNFITANPAWSKAVFISPYNSQNAVARSMLGLTTQTVDSSQG 5848
Query 5863 SEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVA 5922
SEY YVIF QT +TAH+ N+NRFNVAITRA+ GILC+M+ + L++ L+FT L
Sbjct 5849 SEYQYVIFCQTADTAHANNINRFNVAITRAQKGILCVMTSQALFESLEFTELSFTNYK-- 5906
Query 5923 TLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLIS 5981
LQ++ VTGLFKDCS+ +GL P APT++SVD K+KT + LCV++ +P ++ Y R+IS
Sbjct 5907 -LQSQIVTGLFKDCSRETSGLSPAYAPTYVSVDDKYKTSDELCVNL-NLPANVPYSRVIS 5964
Query 5982 MMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVN 6041
MGFK++ V GYP +FITREEA+R VR+WIGFDVEG HA+R A GTN+PLQLGFSTGVN
Sbjct 5965 RMGFKLDATVPGYPKLFITREEAVRQVRSWIGFDVEGAHASRNACGTNVPLQLGFSTGVN 6024
Query 6042 LVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKN 6101
V P G VDT + ++A+PPPG+QFKHL+PLM+KG W +VR +IVQMLSDTL
Sbjct 6025 FVVQPVGVVDTEWGNMLTGIAARPPPGEQFKHLVPLMHKGAAWPIVRRRIVQMLSDTLDK 6084
Query 6102 LSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYV 6161
LSD FV WAHGFELTS YF KIG E+ CC+C+RRA +S+ +YACW HS G+DYV
Sbjct 6085 LSDYCTFVCWAHGFELTSASYFCKIGKEQKCCMCNRRAAAYSSPLQSYACWTHSCGYDYV 6144
Query 6162 YNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEY 6221
YNPF +DVQQWG+ GNL +NHD YC VH AHVAS DAIMTRCLA+H CF++RVDW IEY
Sbjct 6145 YNPFFVDVQQWGYVGNLATNHDRYCSVHQGAHVASNDAIMTRCLAIHSCFIERVDWDIEY 6204
Query 6222 PIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPC 6281
P I E K+N+ CR V+ VV+AALLA F ++DIGNPK I V V+W ++DAQP
Sbjct 6205 PYISHEKKLNSCCRIVERNVVRAALLAGSFDKVYDIGNPKGIPIVDDPVVDWHYFDAQPL 6264
Query 6282 SDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDG 6341
+ K+++LFY+ S +F DG+CLFWNCNV +YP N+IVCRFDTRV S NLPGCDG
Sbjct 6265 TR---KVQQLFYTEDMAS-RFADGLCLFWNCNVPKYPNNAIVCRFDTRVHSEFNLPGCDG 6320
Query 6342 GSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGK-QVVSDIDYVPLKSATCIT 6400
GSLYVNKHAFHTPA+D SAF +LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT
Sbjct 6321 GSLYVNKHAFHTPAYDVSAFRDLKPLPFFYYSTTPCEVHGNGSMIEDIDYVPLKSAVCIT 6380
Query 6401 RCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFN 6460
CNLGGAVCR HA EYR Y++AYN++ ++GF LW YK FD YNLW+TFT++Q LEN+AFN
Sbjct 6381 ACNLGGAVCRKHATEYREYMEAYNLVSASGFRLWCYKTFDIYNLWSTFTKVQGLENIAFN 6440
Query 6461 VVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPE 6520
V +GHF G +GE+PV+++N+ ++TK D+ +FENKTTLP N+AFEL+AKR ++ P+
Sbjct 6441 FVKQGHFIGVEGELPVAVVNDKIFTKSGVNDICMFENKTTLPTNIAFELYAKRAVRSHPD 6500
Query 6521 VKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVD 6580
K+L+NL DI V+WDY+R +TIGVC TDI IC FD R +
Sbjct 6501 FKLLHNLQADICYKFVLWDYERSNIYGTATIGVCKYTDIDVNSALNIC------FDIRDN 6554
Query 6581 GQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQ---FNYYKKVDGV 6637
G ++ F + N + I++ +K VGP A NG + V Q F YKKV+
Sbjct 6555 GSLEKFMSTPNAIFISDRKIKKYPCMVGPDYAYFNGAIIRDSDVVKQPVKFYLYKKVNNE 6614
Query 6638 VQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQL 6697
E +TQSR+ +F P S ME DFL D FI++Y LE YAFEH+VYGDFSH+ L
Sbjct 6615 FIDPTECIYTQSRSCSDFLPLSDMEKDFLSFDSDVFIKKYGLENYAFEHVVYGDFSHTTL 6674
Query 6698 GGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEI 6757
GGLHLLIGL K+ +E +E+ + ST+ NYFIT+ T + K VCSVIDL LDDFV I
Sbjct 6675 GGLHLLIGLYKKQQEGHIIMEEMLKGSSTIHNYFITETNTAAFKAVCSVIDLKLDDFVMI 6734
Query 6758 IKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQR 6817
+KSQDL VVSKVVKV ID T I FMLWCKDG V+TFYP+LQ+S W+PG AMP+L+K+Q
Sbjct 6735 LKSQDLGVVSKVVKVPIDLTMIEFMLWCKDGQVQTFYPRLQASADWKPGHAMPSLFKVQN 6794
Query 6818 MLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVA 6877
+ LE+C+L NY S +P+G+ MN+AKY QLCQYLNT TLAVP NMRVIHFGAGSDKG+A
Sbjct 6795 VNLERCELANYKQSIPMPRGVHMNIAKYMQLCQYLNTCTLAVPANMRVIHFGAGSDKGIA 6854
Query 6878 PGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNV 6937
PGT+VLRQWLPT +++D+DLN+FVSDAD TL GDC TV + DL+ISDMYDP TKNV
Sbjct 6855 PGTSVLRQWLPTDAIIIDNDLNEFVSDADITLFGDCVTVRVGQQVDLVISDMYDPTTKNV 6914
Query 6938 TKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNA 6997
T N+SK FFTY+C I LALGGSVAIKITEHSW+ +LY+LMG FAWWT F TN NA
Sbjct 6915 TGSNESKALFFTYLCNLINNNLALGGSVAIKITEHSWSVELYELMGKFAWWTVFCTNANA 6974
Query 6998 SSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAV 7057
SSSE FL+G NYLG +E IDG MHANYIFWRN+ P+ LS+YSLFD+SKF LKL+GT V
Sbjct 6975 SSSEGFLLGINYLGTIKENIDGGAMHANYIFWRNSTPMNLSTYSLFDLSKFQLKLKGTPV 7034
Query 7058 MSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
+ LKE QIN++++SLLS+G+L+IR+N+ + +S+DVLVN
Sbjct 7035 LQLKESQINELVISLLSQGKLLIRDNDTLSVSTDVLVN 7072
Score = 275 bits (703), Expect = 1e-71, Method: Compositional matrix adjust.
Identities = 298/1189 (25%), Positives = 516/1189 (43%), Gaps = 143/1189 (12%)
Query 101 GETLGVLVPHVGEIPVAYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQEN 160
G+ +G+ P+ E+ + +LLRK G GG+ Y ++ + + +DF+ +
Sbjct 123 GKPIGMFFPYDIELVTGKQNILLRKYGR---GGYHYTP--FHYERDNTSCPEWMDDFEAD 177
Query 161 WNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCT-LSEQL 219
K++ + L+++L GG T VD CG DG P+ L+A+ G + +
Sbjct 178 PKGKYA----QNLLKKLIGGDVTP-VDQYMCGVDGKPISAYAFLMAKDGITKLADVEADV 232
Query 220 DFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNS 279
G + + + + W+ ER + Y Q+ F I + D P++ F L
Sbjct 233 AARADDEGFITLKNNLYRLVWHVERKDVPYPKQSIFTINSVVQKDGVENTPPHY-FTLGC 291
Query 280 IIKTIQPR----------VEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGET 329
I T+ PR +++K L F G+ S + S ++C CG
Sbjct 292 KILTLTPRNKWSGVSDLSLKQKLLYTFYGK-------ESLENPTYIYHSAFIECGSCGND 344
Query 330 SWQTGDFVKATCEFCGTENLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGP--EHSLAE 386
SW TG+ ++ CG + + G + NA++ CP +HS+A+
Sbjct 345 SWLTGNAIQGFACGCGASYTANDVEVQSSGMIKPNALLCATCPFAKGDSCSSNCKHSVAQ 404
Query 387 ---YHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGS 443
Y +E I T+ FGG ++Y GC Y+VPRA + + + G
Sbjct 405 LVSYLSER-CNVIADSKSFTLIFGGVAYAYFGCEEGTMYFVPRAKSVVS-RIGDSIFTGC 462
Query 444 EGLNDNLLEI----LQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAF 499
G + + +I L++ + ++N VG+F +N+ + IL+ + + + +KG+
Sbjct 463 TGSWNKVTQIANMFLEQTQHSLNFVGEFVVNDVVLAILSGTTTNVDKIRQLLKGVTLDKL 522
Query 500 KQIVESCGNFKVTKGKAKKGAWNIG----EQKSILSPLYAFAS--EAARVVRSIFSRTLE 553
+ + + VT G A N+G + +I +P E+ + V +I +
Sbjct 523 RDYLADY-DVAVTAGPFMDNAINVGGTGLQYAAITAPYVVLTGLGESFKKVATIPYKVCN 581
Query 554 TAQNSV-----RVLQKAAITILD-GISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQ 607
+ ++++ VL + +D G+S +S L D + DL+ V Y ++Q
Sbjct 582 SVKDTLTYYAHSVLYRVFPYDMDSGVSSFSELLFDCV----DLS----VASTYFLVRLLQ 633
Query 608 -LTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
T +++ I + + +LD E + FL D + + A V
Sbjct 634 DKTGDFMSTIITSCQTAVSKLLDTCFEATEATFNFLLDLAGLFRIFLRNAYVYTSQGFVV 693
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKA-LNLGETFVTHSKGLYRKCVKSR- 724
++ V+ L+NK + L + G+ + A + G + G Y CV ++
Sbjct 694 VNGKVSTLVKQVLDLLNKGMQLLHTKVSWAGSNISAVIYSGRESLIFPSGTYY-CVTTKA 752
Query 725 ----EETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDL-----QPLEQPTSEAVE 775
++ +++P + K+ + G PT+ T V + ++ LEQ + +
Sbjct 753 KSVQQDLDVILPGEFSKKQL---GLLQPTDNSTTVSVTVSSNMVETVVGQLEQTNMHSPD 809
Query 776 APLVGTPVCINGLMLLEIKDTEKYCALAP---NMMVTNNTFTLKGGAPTK-VTFGDDTVI 831
+VG V I+ + + K+ + + A P N F LKGGAP K V FG D V
Sbjct 810 V-IVGDYVIISEKLFVRSKEEDGF-AFYPACTNGHAVPTLFRLKGGAPVKKVAFGGDQVH 867
Query 832 EVQGYKSVNITFELDERIDKVL-NEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL 890
EV +SV + + + +D +L + + V+ + EFA VV + V L + +
Sbjct 868 EVAAVRSVTVEYNIHAVLDTLLASSSLRTFVVDKSLSIEEFADVVKEQVSDLLVKLLRGM 927
Query 891 TPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEE---EEFEPSTQY 947
DLD++ A Y F+ G+ +S M S +P + DEE + E EE E
Sbjct 928 PIPDFDLDDFIDAPCYCFNAEGDASWSSTMIFSLHPVECDEECSEVEASDLEEGESECIS 987
Query 948 EYGTE----------DDY-----QGKPL-EFGATSAALQPEEEQEEDWLDDDSQQTVGQQ 991
E TE D++ + PL E + ++Q E + E ++D +Q +
Sbjct 988 ETSTEQVDVSHEISDDEWAAAVDEAFPLDEAEDVTESVQEEAQPVEVPVEDIAQVVIADT 1047
Query 992 DGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIE--------------------------- 1024
+T + VEV PQ+ ++L QTI+
Sbjct 1048 L----QETPVVSDTVEVPPQV-VKLPSEPQTIQPEVKEVAPVYEADTEQTQSVTVKPKRL 1102
Query 1025 -----VNSFSGYLK--LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
V+ S + +T+ V I D ++ AK +V+VNAAN +LKHGGG+AGA+N
Sbjct 1103 RKKRNVDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHGGGIAGAINA 1162
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
A+ A+Q ESD+YI GPL+VG S +L GH+LAK+ LHVVGP+ +D+ LL Y+
Sbjct 1163 ASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSLLSKCYKA 1222
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKL 1186
N + +++ PL+SAGIFG P S + +T V + V +++Y L
Sbjct 1223 MNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSL 1271
>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182
Score = 5976 bits (15503), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3006/5830 (52%), Positives = 3968/5830 (68%), Gaps = 162/5830 (3%)
Query 1391 VCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPL 1450
+C + A ++ + + + VD G ++Y Y+SK + +I N + + MP+
Sbjct 1379 ICTDQSANAKLLKGRGVDLTKKTQTVD-GVKYYLYSSKDPLTDIITAANAC-KGICAMPI 1436
Query 1451 GYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGS 1510
GYVTHGL+L +A + ++ + VP ++S D V N + + +TPE+ FI T+ G
Sbjct 1437 GYVTHGLDLAQAGQQVKKITVPYVCLLASKDQVPILNSDV--AVQTPEQSFINTVIANGG 1494
Query 1511 YKDWSY-SGQSTQLGIEF---LKRGDKSVYYTSNPTTFHLDGEV-ITFDNL---KTLLSL 1562
Y W +G+ G+ + L D+++ Y N + + G++ + FD+L +T L+
Sbjct 1495 YHCWHLVTGELIVKGVSYRKLLNWSDQTICYADN-KFYVVKGQIALPFDSLEKCRTYLTS 1553
Query 1563 R--EVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
R + + + V T+D +N T V++ + TY Q G + G+D++ P G+ Y+
Sbjct 1554 RAAQQKNVDVLVTIDGVNFRTVVLNNTTTYRVQLGSVFYKGSDISDTIPTEKMSGEAVYL 1613
Query 1621 LPN-DDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATA 1679
N + + E Y T D +FL RY S L KKWKY +G+ S+K NNCY+
Sbjct 1614 ADNLSEAEKAVLSEVYGTADTAFLHRYYSLLALVKKWKYTVHDGVKSLKLNSNNCYVNVT 1673
Query 1680 LLTLQQI-ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQH 1738
+L L + E+KF PALQ AY + + G++ F ALI+AY + T GE D + +
Sbjct 1674 MLMLDMLKEIKFIVPALQAAYLKHKGGDSTEFIALIMAYGDCTYGEPDDASRLLHTILSK 1733
Query 1739 ANLDS-CKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYL 1797
A L + K V C CG Q TT G++A +Y+G S ++ + C CG + L
Sbjct 1734 AELTTQAKMVWRQWCNVCGVQDTTTTGLKACIYVGMNSLDELHATHEECCQCGDVRKRQL 1793
Query 1798 VQQESPFVMMSAPPAQYELKHGTFTCASEYTG-------NYQCGHYKHITSKETL-YCID 1849
V+ +P++++S + + + +YT GHY H+ K+ L Y D
Sbjct 1794 VEHNAPWLLLSGLNEAKVMTPTSQSAGPDYTAFNVFQGVETSVGHYLHVRVKDNLLYKYD 1853
Query 1850 GALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTE 1909
L+K+S+ K +TDV+Y + Y+ V Y LDG ++DP L +Y KD YFT+
Sbjct 1854 SGSLSKTSDMKCKMTDVYYPKQRYSADCNVVVYSLDGNTWADVDPDLSAFYMKDGKYFTK 1913
Query 1910 QPI------DLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGY--KKPASRELKVTFFP 1961
+P+ ++ Y N+ + + N L G+ KP S++L +FFP
Sbjct 1914 KPVIEYSPATILSGSVYTNSCLVGHDGTIGSDAISSSFNNLLGFDNSKPVSKKLTYSFFP 1973
Query 1962 DLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVET 2021
D GDV+ +Y Y P +K GA L KPI+W N+ + A K N +R ++ PV
Sbjct 1974 DFEGDVILTEYSTYDPIYKNGAMLHGKPILWVNNSKFDSALNKFNRATLRQVYDIAPVTL 2033
Query 2022 SNSFDVLKSEDAQGMDNLAC-EDLKPVSE-EVVENPTIQKDVLECNVKTTEVVGD---II 2076
N + VL+ Q ++ A ED KP S +V E+ + +++C V D +
Sbjct 2034 ENKYTVLQDNQIQQVEVEAPKEDAKPQSPVQVAEDIDNKLPIIKCKGLKKPFVKDGYSFV 2093
Query 2077 LKPANNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPW 2135
P + + + +G DL A YVD N L + K N S + + T+ L+ + +
Sbjct 2094 NDP--QGVNVIDTLGIDDLRALYVDRNLRLIVLKENNWSALFNIHTVEKGDLSVIAASGS 2151
Query 2136 DT----IANYAKPFLNKVVSTTTNIVT---RCLNRVCTNYMP------YFFTLLLQLC-- 2180
T I A + S T N+ T + L R+ N + F LL L
Sbjct 2152 ITRRVKILLGASSLFAQFASVTVNVTTAMGKALGRMTRNVITNTGIIGQGFALLKMLLIL 2211
Query 2181 --TFTRSTN-SRIKASMPTTIAKNTVKS-VGKFCLEASFNYLKSPNFSKLINIIIWFLLL 2236
TF +S N S +K + V + V K C A+++ L F ++ LL
Sbjct 2212 PFTFWKSKNQSTVKVEVGALRTAGIVTTNVVKQCASAAYDVLVV-KFKRIDWKSTLRLLF 2270
Query 2237 SVC------------------LGSLIYSTAALGVLM------SNLGMPSYCTGYREGYLN 2272
+C L S + A G+L S LG+ S C G E Y N
Sbjct 2271 LICTTGLLLSSLYYLFLFHQVLTSDVMLDGAEGMLATYRELRSYLGIHSLCDGMVEAYRN 2330
Query 2273 STNVTIATYCTG-SIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAY 2331
+ + +C+ S C+ CL G DSL Y + + IQ ++S+ ++ V E+ LAY
Sbjct 2331 -VSYDVNDFCSNRSALCNWCLIGQDSLTRYSAFQMIQTHVTSYVINIDWVWFVMEFALAY 2389
Query 2332 ILFTRFFYVLGLAAIMQLFFSYFA--VHFISNSWLMWLIINLVQMAPISAMVRMYIFFAS 2389
+L+T F VL L Q FFSY V++ S ++L+ V P+ +VR+Y F A
Sbjct 2390 VLYTSTFNVLLLVVSSQYFFSYTGAFVNWRSYNYLVSGYFFCVTHIPLLGLVRIYNFLAC 2449
Query 2390 FYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHN 2449
+++ + Y HV++GC + C++CYKRNR TRVE +T+V G +R+FY+ ANGG FC HN
Sbjct 2450 LWFLRRFYNHVINGCKDTACLLCYKRNRLTRVEASTVVCGSKRTFYIVANGGTSFCCRHN 2509
Query 2450 WNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAG 2509
WNCV+CDT G+TFI +EVA DL+ +R + PTD+S Y V+SVTVK+ + L++ + G
Sbjct 2510 WNCVDCDTAGIGNTFICEEVANDLTTSLRRLVKPTDKSHYYVESVTVKDSVVQLHYSREG 2569
Query 2510 QKTYERHSLSHFVNLDNLRAN---NTKGSLP-INVIVFDGKSKCEESSAKSASVYYSQLM 2565
YER+ L +F NLD L+ T +P N +++D + +E+ A+SA VYYSQ++
Sbjct 2570 ASCYERYPLCYFTNLDKLKFKEVCKTPTGIPEHNFLIYDSSDRGQENLARSACVYYSQVL 2629
Query 2566 CQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVS 2625
+P+LL+D +V+ VGDS E+A KM D+YVN+F S F V +KL LVATA + +
Sbjct 2630 SKPMLLVDSNMVTTVGDSREIASKMLDSYVNSFISLFGVNRDKLDKLVATARDCVKRGDD 2689
Query 2626 LDNVLSTFISAAR-QGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMT 2684
V+ TF AAR V+SDVET +V+ L+ +++ D+++T + NNY+ +Y K +++
Sbjct 2690 FQTVIKTFTDAARGPAGVESDVETSSIVDALQYAYKHDLQLTTEGFNNYVPSYIKPDSVA 2749
Query 2685 PRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTC 2744
DLG ID +A +N ++ N A IWN D+M LS+ L++QIR A +K N+PF+LT
Sbjct 2750 TADLGCLIDLNAASVNQTSIRNANGACIWNSSDYMKLSDSLKRQIRIACRKCNIPFRLTT 2809
Query 2745 ATTRQVVNVVTTKIA---LKGG------KIVNNWLKQLIKVTLVFLFVAAIFYLITPVHV 2795
+ R N+++ K + L GG K+ + K VTLV +A + YL P
Sbjct 2810 SRLRSADNILSVKFSATKLSGGAPKWLLKLRDFTWKSYCVVTLVVFAMAVLSYLCLPAFN 2869
Query 2796 MSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQR-GGSYTNDKACPLI 2854
MS+ + I+ YK ++ G+ RDI +DTCFANK+ F WF++ GG + ND +CP+
Sbjct 2870 MSQVSFHEDRILTYKVVENGIIRDITPSDTCFANKYQSFSKWFNEHYGGLFNNDISCPVT 2929
Query 2855 AAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACV 2914
AVI G VP LP + L F+ RVF++ N+CYTP+ I Y F+ S CV
Sbjct 2930 VAVIAGVAGARVPNLPANVAWVGRQIVL-FVSRVFASSNNVCYTPTAEIPYERFSDSGCV 2988
Query 2915 LAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSI-IQFPNTYLEGSV 2973
LA+ECT+F+DA GK PYCYD VL G+ AY+ ++P RY + D + I+FP E ++
Sbjct 2989 LASECTLFRDAEGKINPYCYDPTVLPGASAYDQMKPHVRYDMYDSDMYIKFPEVVFESTL 3048
Query 2974 RVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTP 3033
R+ T + YCR G+CE + GVC++T+G W + ND+Y + PGV+CG + +++ +
Sbjct 3049 RITKTLATRYCRFGSCEDANEGVCITTNGSWAIYNDHYANKPGVYCGDNYFDIVRRLGLS 3108
Query 3034 LIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLC 3093
L QP+ +S S+ G ++ I +T YY + +RA +Y+ L++ LC
Sbjct 3109 LFQPVTYFQLSTSLALGVMLCIFLTIAFYYVNKVKRALADYTQCAVVAVAAALLNSLCLC 3168
Query 3094 LTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHF 3153
L Y+ +Y Y TFYLT + +F+ H+ W VMF +VP W+ AYI+ + +H
Sbjct 3169 FVVSNPLLVLPYTALYYYATFYLTGEPAFVMHVSWFVMFGTVVPIWMVFAYIVGVCLRHL 3228
Query 3154 YWFFSNYLKRRV-VF-NGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALY 3211
W + + K+ V VF +G +F++AA F++NK+ Y+ LR+ + YNRYL+++
Sbjct 3229 LWVMAYFSKKHVEVFTDGKLNCSFQDAAANIFVINKDTYVALRNSI--TQDSYNRYLSMF 3286
Query 3212 NKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAF 3271
NKYKY+SGAMDT SYREA+ HL KAL +S +GSDVL+QPP S+TS+VLQSG KMA
Sbjct 3287 NKYKYYSGAMDTASYREASAAHLCKALQVYSETGSDVLFQPPNCSVTSSVLQSGLVKMAA 3346
Query 3272 PSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLV 3331
PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+ LL+ K+N +F+V
Sbjct 3347 PSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDALLVSKTNLSFIV 3406
Query 3332 Q---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGV 3388
Q LRV+GH+M +LKL V++ANP+TP Y F ++PG +FSVLACYNG P+GV
Sbjct 3407 QKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFSVLACYNGRPTGV 3466
Query 3389 YQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPF 3448
+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H G +G YG F
Sbjct 3467 FMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHTGCAFDGVMYGAF 3526
Query 3449 VDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY-EPLTQ 3507
DRQ Q +D T+N++AWLYAA++NG WF+ T + FN AM + E +
Sbjct 3527 EDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEWAMSNQFTEFIGT 3586
Query 3508 DHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVT 3567
VD+L + +TG++V + ++ + L G G+TILG+++LEDEFTP DV Q GV
Sbjct 3587 QSVDML---AHKTGVSVEQLLYAI-QTLHKGFQGKTILGNSMLEDEFTPDDVNMQVMGVV 3642
Query 3568 FQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMM 3627
QS VKR G HWL T+L + + +Q T+++++ +L+E L ++ + A M+
Sbjct 3643 MQSGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLTPLVLCVMACVML 3702
Query 3628 FVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCV 3683
VKHKH FL LFLLP+ + Y N+VY P +S ++ + WL+ + D
Sbjct 3703 TVKHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPASVYMRTTH-TDLG 3761
Query 3684 MYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSN 3743
+Y S L ++ R + + L + + Y G+ ++ + ++TS+
Sbjct 3762 VYLSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPLTYLMFLTTLTSD 3820
Query 3744 YSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
Y+ V + +A+ + Y P ++ ++L+Y +GYFCT YFG+F LLN
Sbjct 3821 YTVTVFLAVNVAKFFARVVFLYAPHAGFIFPEVKLVLLMYLAVGYFCTVYFGVFSLLNLK 3880
Query 3804 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMS 3863
R+ LGVYDY VSTQEFRY+ GL P+NS +A +LN+KL+G+GG PCIK+A+VQSK++
Sbjct 3881 LRVPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTPCIKIASVQSKLT 3940
Query 3864 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3923
D+KCTSVVLLSVLQQL +E++SK WA CV+LHNDIL A D TEAF+ V L + L+S
Sbjct 3941 DLKCTSVVLLSVLQQLHLEANSKAWAHCVKLHNDILAATDPTEAFDNFVCLFATLMSFSA 4000
Query 3924 AVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKK 3982
VD+ L ++LD+ + LQA SEFS L SYA AQ +Y++A+ +GD S VLK L+K
Sbjct 4001 NVDLEALASDLLDHPSVLQATLSEFSHLASYAELEAAQSSYQKALNSGDASPQVLKALQK 4060
Query 3983 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4042
++N+AK+ +++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDN
Sbjct 4061 AVNIAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDN 4120
Query 4043 DALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVV 4102
D LN +I+NAR+GCVPL+++PL + KL VVIPD + + +YA ALW+I +
Sbjct 4121 DVLNGVISNARNGCVPLSVVPLCASNKLRVVIPDITIWNKVVTWPSLSYAGALWDISLIN 4180
Query 4103 DADSKIVQLSEISMDNSPNLAWPLIVTALRA-NSAVKLQNNELSPVALRQMSCAAGTTQT 4161
+ D ++V+ S+++ N +L WPL++ RA +SAV LQNNE+ P L+ M +AG
Sbjct 4181 NVDGEVVKSSDVTETNE-SLTWPLVLECTRAASSAVTLQNNEIRPSGLKTMVVSAGIDHA 4239
Query 4162 ACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPK 4221
C + ++LAYY +G + ++ +LS+ LKWA+ DG I EL+PPC+F+ PK
Sbjct 4240 NC-NTSSLAYYEPVEGRKMLMGILSENAHLKWAKVEGRDGFVNI--ELQPPCKFLIAGPK 4296
Query 4222 GPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYK 4281
GP+V+YLYF+K LNNL+RG +LG +AATVRLQAG+ TE NS+VLS F+VD KAY
Sbjct 4297 GPEVRYLYFVKNLNNLHRGQLLGHIAATVRLQAGSNTEFAINSSVLSAVTFSVDPGKAYL 4356
Query 4282 DYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKG 4341
D++ +GG P+TNCVKML TGTG A++V PEAN DQ+++GGAS CLYCR HI+HP+ G
Sbjct 4357 DFVNAGGAPLTNCVKMLTPKTGTGIAVSVKPEANADQDTYGGASVCLYCRAHIEHPDVTG 4416
Query 4342 FCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
C KGK+VQ+P DPVGF L+NT C VC W G+GC+CD LR + + +FLN
Sbjct 4417 VCKFKGKFVQVPLH-IRDPVGFCLQNTPCNVCQFWIGHGCNCDALRGTTIPQSKDSNFLN 4475
Query 4402 RVCG-VSAARLTPCGTGTSTDVVYRAFDI--YNDKVAGFAKFLKTNCCRFQEKDEDDNLI 4458
RV G + AR+ PC +G +TDVV+RAFDI Y KVAG K+ KTN CRF E D++ + +
Sbjct 4476 RVRGSIVNARIEPCASGLTTDVVFRAFDICNYKAKVAGIGKYYKTNTCRFVEVDDEGHRL 4535
Query 4459 DSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMAD 4518
DS+FVVKRHT NY+ E+ Y+L+KDC AVA HDFF F +D PHI RQRLT+YTM D
Sbjct 4536 DSFFVVKRHTMENYELEKRCYDLVKDCDAVAVHDFFIFDVDKVKTPHIVRQRLTEYTMMD 4595
Query 4519 LVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQAL 4578
LVYALRHFD+ NC+ LK ILV Y CCD YF+ K W+DFVENP+++ VY LGER+RQA+
Sbjct 4596 LVYALRHFDQNNCEVLKSILVKYGCCDASYFDNKLWFDFVENPNVISVYHKLGERIRQAV 4655
Query 4579 LKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILT 4638
L TV+FCD M +G+VGVLTLDNQDLNG WYDFGDF+ T PG+GV +VDSYYS LMP+L+
Sbjct 4656 LNTVKFCDQMVKSGLVGVLTLDNQDLNGKWYDFGDFVITQPGAGVAIVDSYYSYLMPVLS 4715
Query 4639 LTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRC 4698
+T L AE+H D DLTKP I+W LL+YD+T+ ++ LF++YFK WDQ YHPNCVNC DDRC
Sbjct 4716 MTNCLAAETHRDCDLTKPLIEWPLLEYDYTDYKIGLFEKYFKXWDQQYHPNCVNCTDDRC 4775
Query 4699 ILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRL 4758
+LHCANFNVLFS P TSFGP+VRKIFVDGVPFV+S GYH++ELG+V N DV+LH RL
Sbjct 4776 VLHCANFNVLFSMTLPGTSFGPIVRKIFVDGVPFVISCGYHYKELGLVMNMDVSLHRHRL 4835
Query 4759 SFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSK 4818
S KEL++YAADPAMH AS + L D RT CFSVAALT + FQTV+PGNFNKDFYDF VSK
Sbjct 4836 SLKELMMYAADPAMHIASASALWDLRTPCFSVAALTTGLTFQTVRPGNFNKDFYDFVVSK 4895
Query 4819 GFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGG 4878
GFFKEGSSV L+HFFFAQDG+AAI+DY YY YNLPTMCDI+Q+LF +EVVD+YF+ YDGG
Sbjct 4896 GFFKEGSSVTLRHFFFAQDGHAAITDYSYYAYNLPTMCDIKQMLFCMEVVDRYFEIYDGG 4955
Query 4879 CINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKY 4938
C+NA++VIVNNLDKSAG PFNK+GKAR+YY+S+SY++QD LFA TKRNV+PTITQMNLKY
Sbjct 4956 CLNASEVIVNNLDKSAGHPFNKFGKARVYYESLSYQEQDELFAMTKRNVLPTITQMNLKY 5015
Query 4939 AISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVY 4998
AISAKNRARTVAGVSI STMTNRQ+HQK+LKS+AATRG+T VIGT+KFYGGW MLKT+Y
Sbjct 5016 AISAKNRARTVAGVSILSTMTNRQYHQKMLKSMAATRGSTCVIGTTKFYGGWDFMLKTLY 5075
Query 4999 SDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEM 5058
DV+NPHLMGWDYPKCDRAMPNM RI ASL+LARKH+TCC+ + RFYRLANECAQVLSE
Sbjct 5076 KDVDNPHLMGWDYPKCDRAMPNMCRIFASLILARKHSTCCTNTDRFYRLANECAQVLSEY 5135
Query 5059 VMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHR 5118
V+CGG YVKPGGTSSGDATTAYANSVFNI QA TANV+AL+ +GN I D+ V+++Q
Sbjct 5136 VLCGGGYYVKPGGTSSGDATTAYANSVFNILQATTANVSALMGANGNTIVDEEVKDMQFE 5195
Query 5119 LYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVL 5178
LY +YR D FV+ +YA+L KHFSMMILSDD VVC+NS YA++G +ASI+NFK L
Sbjct 5196 LYVNVYRKSQPDPKFVDRYYAFLNKHFSMMILSDDGVVCYNSDYATKGYIASIQNFKETL 5255
Query 5179 YYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDD 5238
YYQNNVFMSEAKCW ETDL KGPHEFCSQHT+ +K GDD +LPYPDPSRIL AGCFVDD
Sbjct 5256 YYQNNVFMSEAKCWVETDLKKGPHEFCSQHTLFIKDGDDGYFLPYPDPSRILSAGCFVDD 5315
Query 5239 IVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVM 5298
IVKTDGTLM+ERFVSLAIDAYPLTKH + EY +VF +YLQYI KL+ +LTGHMLD YSVM
Sbjct 5316 IVKTDGTLMVERFVSLAIDAYPLTKHDDPEYQNVFWVYLQYIEKLYKDLTGHMLDSYSVM 5375
Query 5299 LTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHV 5358
L DN++++WE FY +YT T LQAVG+CV+C+SQTSLRCG CIRRPFLCCKCCYDHV
Sbjct 5376 LCGDNSAKFWEESFYRDLYTAPTTLQAVGSCVVCHSQTSLRCGTCIRRPFLCCKCCYDHV 5435
Query 5359 ISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYK 5418
I+T HK+VLSV+PYVCNAPGCDV DVT+LYLGGMSY+C H+P SFPLCANG VFGLYK
Sbjct 5436 IATPHKMVLSVSPYVCNAPGCDVADVTKLYLGGMSYFCIDHRPVCSFPLCANGLVFGLYK 5495
Query 5419 NTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATV 5478
N C GS +VT+FN +ATCDWT +GDY LANT TE LKLFAAETL+ATEE K SY IAT+
Sbjct 5496 NMCTGSPSVTEFNRLATCDWTESGDYTLANTTTEPLKLFAAETLRATEEASKQSYAIATI 5555
Query 5479 REVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGT 5538
+E++ +REL L WE GK +PPLNRNYVFTGY +TKNSKVQ+GEY FE+ DY DAV Y+ +
Sbjct 5556 KEIVGERELLLVWEAGKAKPPLNRNYVFTGYHITKNSKVQLGEYVFERIDYSDAVSYKSS 5615
Query 5539 TTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGM 5598
TTYKL VGD FVLTSH+V L APT+V QE YV+ITGLYPTL + +EF+++VAN+QK G
Sbjct 5616 TTYKLAVGDIFVLTSHSVATLQAPTIVNQERYVKITGLYPTLTVPEEFANHVANFQKAGF 5675
Query 5599 QKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5658
K+ T+QGPPGTGKSHFAIGLA+YYP+AR+VYTACSHAAVDALCEKA KYL I KCSRII
Sbjct 5676 SKFVTVQGPPGTGKSHFAIGLAIYYPTARVVYTACSHAAVDALCEKAFKYLNIAKCSRII 5735
Query 5659 PARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK 5718
PA+ARVEC+D+FKVN T QY+F T+NALPET+ADI+V DE+SM TNYDLSV+NAR++AK
Sbjct 5736 PAKARVECYDQFKVNETNSQYLFSTINALPETSADILVVDEVSMCTNYDLSVINARIKAK 5795
Query 5719 HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSA 5778
H VY+GDPAQLPAPRTLLT+GTLEPE FNSV RLM +GPD+FL C RCP EIV+TVSA
Sbjct 5796 HIVYVGDPAQLPAPRTLLTRGTLEPENFNSVTRLMCNLGPDIFLSVCYRCPEEIVNTVSA 5855
Query 5779 LVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISP 5838
LVY+NKL A K S QCFK+ YKG +THD SSAINRPQ+ V+ F+ NP W KAVFISP
Sbjct 5856 LVYNNKLVAKKPASGQCFKILYKGSVTHDASSAINRPQLNFVKSFIAANPNWSKAVFISP 5915
Query 5839 YNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILC 5898
YNSQNAVA +LGL TQTVDSSQGSEY YVIF QT +TAH+ N+NRFNVA+TRA+ GILC
Sbjct 5916 YNSQNAVARSVLGLTTQTVDSSQGSEYPYVIFCQTADTAHANNINRFNVAVTRAQKGILC 5975
Query 5899 IMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKF 5958
+M+ + L+D L+F + + N LQ++ VTGL+KDCS+ +GLHP APT++SVD K+
Sbjct 5976 VMTSQALFDSLEFAEVSL---NNYKLQSQIVTGLYKDCSRESSGLHPAYAPTYVSVDDKY 6032
Query 5959 KT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVE 6017
KT + LCV++ +P ++ Y R+IS MGFK++ + YP +FITR+EAIR VR+WIGFDVE
Sbjct 6033 KTSDELCVNL-NVPANVPYSRVISRMGFKLDASIPNYPKLFITRDEAIRQVRSWIGFDVE 6091
Query 6018 GCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPL 6077
G HA+R A GTN+PLQLGFSTGVN V P G VDT + + ++A+PPPG+QFKHL+PL
Sbjct 6092 GAHASRNACGTNVPLQLGFSTGVNFVVQPVGVVDTEWGSMLTSIAARPPPGEQFKHLVPL 6151
Query 6078 MYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDR 6137
M KG W +VR +IVQMLSDTL LSD FV WAHGFELTS YF KIG E+ CC+C+R
Sbjct 6152 MNKGAAWPIVRRRIVQMLSDTLDKLSDYCTFVCWAHGFELTSASYFCKIGKEQRCCMCNR 6211
Query 6138 RATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASC 6197
RA+ +S+ +YACW HS G+DYVYNPF +DVQQWG+ GNL +NHD YC VH AHVAS
Sbjct 6212 RASTYSSPLHSYACWSHSSGYDYVYNPFFVDVQQWGYIGNLATNHDRYCSVHQGAHVASN 6271
Query 6198 DAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDI 6257
DA+MTRCLA+H+CF++RV+W I YP I E ++N+ CR V+ VV+AALLA +F ++DI
Sbjct 6272 DAVMTRCLAIHDCFIERVEWDITYPYISHEKRLNSCCRAVERNVVRAALLAGRFERVYDI 6331
Query 6258 GNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRY 6317
GNPK I V V+W +YDAQP S K+++LFY+ + F+DG+CLFWNCNV RY
Sbjct 6332 GNPKGIPIVDDPVVDWHYYDAQPLSK---KVQQLFYT-EDCAKNFSDGLCLFWNCNVPRY 6387
Query 6318 PANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPC 6377
P N+IVCRFDTRV S NLPGCDGGSLYVNKHAFHTPA+D SAF +LK LPFFYYS +PC
Sbjct 6388 PNNAIVCRFDTRVHSEFNLPGCDGGSLYVNKHAFHTPAYDASAFRDLKPLPFFYYSTTPC 6447
Query 6378 ESHGK-QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVY 6436
E HG ++ DIDYVPLKSA CIT CNLGGAVCR HA EYR Y++AYN++ ++GF LW Y
Sbjct 6448 EVHGNGNMLEDIDYVPLKSAVCITACNLGGAVCRKHAAEYRDYMEAYNLVSASGFRLWCY 6507
Query 6437 KQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFE 6496
K FD YNLW+TFT++Q LEN+A+NV+ +GHF G +GE+PV+++N+ +YTK D DV +FE
Sbjct 6508 KTFDVYNLWSTFTKIQGLENIAYNVIKQGHFTGVEGELPVAVVNDKIYTKSDVNDVCIFE 6567
Query 6497 NKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSM 6556
NKTTLP N+AFEL+AKR ++ P+ +L NL VD+ V+WDY+R +TIGVC
Sbjct 6568 NKTTLPTNIAFELYAKRAVRSHPDFNLLRNLEVDVCYKFVLWDYERSNIYGSATIGVCKY 6627
Query 6557 TDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNG 6616
TDI IC FD R +G ++ F + NG+LI++ VK V A NG
Sbjct 6628 TDIDVNSALNIC------FDIRDNGSLERFMSLPNGILISDRKVKNYPCIVSSNYAYFNG 6681
Query 6617 VTLIGEAVKTQ-----------FNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDF 6665
+ +Q F YKKV+ Q +TY+T R + +F P S+ME DF
Sbjct 6682 TLIRDNTGNSQSSDGEVKQPVTFYIYKKVNNEFVQFTDTYYTLGRTVSDFTPVSEMEKDF 6741
Query 6666 LELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDS 6725
L L D FI++YKLE YAFEH+VYGDFS + LGGLHLLIGL K+ +E +E+ + +
Sbjct 6742 LALDSDVFIKKYKLEAYAFEHVVYGDFSRTTLGGLHLLIGLYKKHQEGHIIMEEMLKERA 6801
Query 6726 TVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWC 6785
TV NYF+T++ T S K VCSVIDL LDDFV+IIK+ DLSVVSKVVK+ ID T I FMLWC
Sbjct 6802 TVHNYFVTESNTASFKAVCSVIDLKLDDFVDIIKAMDLSVVSKVVKIPIDLTMIEFMLWC 6861
Query 6786 KDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKY 6845
KDG V+TFYP+LQ+ W+PG+AMP+L+K+Q LE C L NY S +P+G+ MN+AKY
Sbjct 6862 KDGQVQTFYPRLQAINDWKPGLAMPSLFKVQNSNLEPCMLPNYKQSIPMPQGVHMNIAKY 6921
Query 6846 TQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDA 6905
QLCQYLNT T+AVP NMRV+HFGAGSDKGVAPG++VLRQWLPT +L+D+DLN++VSDA
Sbjct 6922 MQLCQYLNTCTIAVPANMRVMHFGAGSDKGVAPGSSVLRQWLPTDAILIDNDLNEYVSDA 6981
Query 6906 DSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSV 6965
D TL GDC TV + DL+ISDMYDP TK V + N++K FF Y+C FI+ LALGGSV
Sbjct 6982 DITLFGDCVTVRVGQQVDLLISDMYDPSTKVVGETNEAKALFFVYLCNFIKNNLALGGSV 7041
Query 6966 AIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHAN 7025
AIKITEHSW+A+LY+LMG FAWWT F TN NASSSE FLIG NYLG+ +E IDG VMHAN
Sbjct 7042 AIKITEHSWSAELYELMGRFAWWTVFCTNANASSSEGFLIGINYLGELKEVIDGNVMHAN 7101
Query 7026 YIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNR 7085
YIFWRNT + LS+YSLFD+S+FPLKL+GT V+ LKE QIN++++SLLS+G+LIIR+N+
Sbjct 7102 YIFWRNTTLMNLSTYSLFDLSRFPLKLKGTPVLQLKESQINELVISLLSQGKLIIRDNDT 7161
Query 7086 VVISSDVLVN 7095
+ +S+DVLVN
Sbjct 7162 LSVSTDVLVN 7171
Score = 180 bits (457), Expect = 4e-43, Method: Compositional matrix adjust.
Identities = 248/1066 (23%), Positives = 444/1066 (42%), Gaps = 91/1066 (9%)
Query 13 HVQLSLPVLQVRDVLVR---GFGDSVEEVLSEARQHLKDGTCGLV--EVEKGVLPQLEQP 67
HV L + D++++ F D E + L G+ L + KG + L P
Sbjct 28 HVSLKASLCDAGDLVLKISPWFMDG-ESAYKHVSEQLSKGSKLLFVPQTLKGFIRHLPGP 86
Query 68 YVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETL-----GVLVPHVGEIPVAYRKVL 122
V++ MV +A G G TL G+ P ++ + L
Sbjct 87 RVYLVERLTGGTYSDPFMVNQLAYQNAAGEGVIGTTLQGKRVGMFFPFDADLVTGEFQFL 146
Query 123 LRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAY 182
LRK KG GG+ + D + PY D + ++ L+++L GG +
Sbjct 147 LRK---KGFGGNRFR------DAPWDYNWTPYSDLMDALEADPCGKYSQSLLKKLVGGDF 197
Query 183 TRYVDNNFCGPDGYPLECIKDLLARAG--KASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
T +D CG +G P+ L+A G K + +E D+ R + + + I W
Sbjct 198 TP-IDQYMCGKNGKPIAEFAALMASEGITKLADVEAEVKSRTDSDRYI-VFKNKLYRIVW 255
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+R + +Y Q+ F + + DT + P F + S I+ I P + +
Sbjct 256 NVQRKDVAYSKQSAFTMNSIVQLDTME-DVPRHSFTIGSEIQVIAPSTAVQANGHLNLKQ 314
Query 301 RSVYPV---ASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKE-GATT 356
R +Y + +E N + S + C CG+ SW TG+ V+ CG + +
Sbjct 315 RLLYAFYGKQAVSEPNYIYHSAYVDCTSCGKGSWLTGNAVQGFACDCGAHYCANDVDLQS 374
Query 357 CGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRT--IAFGGCVFSYV 414
G + +NAV+ CP + E +H+L + + K + G+T + +GG +++Y+
Sbjct 375 SGLVRKNAVLLTTCPCNKDGEC--KHTLPQLVSMMTDKCDVEVVGKTFILTYGGVIYAYM 432
Query 415 GCHNKCAYWVPRASANIG----CNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLN 470
GC +++PRA + + TG G S+ L L++ + IN V +F L
Sbjct 433 GCSGGTMHFIPRAKSCVSKIGDAIFTGCTGTWSKVCETANL-FLERAQHAINFVNEFVLT 491
Query 471 EEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSIL 530
E + +L+ ++S + + ++ + + G + VT G +G N+G
Sbjct 492 ETVVALLSGTTSSIEELRDLCRNATFEKVRDYLTPRG-WIVTMGSYIEGVINVGAAGVCN 550
Query 531 SPLYA-----------FASEAARVVR--SIFSRTLETAQNSV--RVLQKAAITILDGISQ 575
+ L A F AA + S TL+ +S+ RV I ++
Sbjct 551 AALNAPFIVLSGLGESFKKVAATPWKLCSSLRETLDHYADSITYRVF---PYDIPCDVTD 607
Query 576 YSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKF 635
Y+ L+D + T A V Y+ V QLT+ +F + + + +
Sbjct 608 YTALLLDCAVLTGASA---YFVARYVDEKVEQLTNL----VFSSCQSAVAAFVQACMSTY 660
Query 636 KEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIII 695
K +F+ D + ++K +S V + ++ F +++K + L ++
Sbjct 661 KATAKFISDMFTLIKVVSERLYVYTSVGFVVVGDYSSQLLKQFMHILSKAMQLLHTTVSW 720
Query 696 GGAKLKAL--NLGETFVTHSKGLYRKCVKSR---EETGLLMPLK-APKEIIFLE----GE 745
G+KL ++ N ++ V S Y + R ++ L++P + K+I LE
Sbjct 721 AGSKLPSVVYNGRDSLVFPSGTYYCVSTQGRSLQDQFDLVIPGDLSKKQIGILEPTPNST 780
Query 746 TLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCI-NGLMLLEIKDTEK-YCALA 803
T+ ++ T V + G L+P ++ + E V VG V I N + + ++D+E + L
Sbjct 781 TVDKKINTNVVEVVVGQLEPTKEHSPELV----VGDYVIISNKIFVRSVEDSETVFYPLC 836
Query 804 PNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSVNITFELDERIDKVL-NEKCSAYT 861
+ + F LKGGAP K V FG + E+ +SV++ +++ +D +L + + +T
Sbjct 837 TDGKIVPTLFRLKGGAPPKGVKFGGEQTKEITAVRSVSVDYDVHPVLDALLAGSELATFT 896
Query 862 VELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMY 921
VE V +F VV D VI+ L + G DL++++ Y+++ G+ +S M
Sbjct 897 VEKDLPVKDFVDVVKDEVIELLSKLLRGYNVDGFDLEDFADTPCYVYNAEGDLAWSSTMT 956
Query 922 CSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLD 981
S P +E EEE D + E E ++ ED+ + A A+ P E+ + D L
Sbjct 957 FSVNPVEEVEEECDDDYVEDEYLSEEMLVEEDEN-----SWAAAVEAVIPMEDVQLDTLV 1011
Query 982 DDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNS 1027
+ + D +E T VEV +E + V EV S
Sbjct 1012 AEIDVSEPADDVAEQASTEE----VEVPSACVLEASQVANAAEVES 1053
Score = 138 bits (347), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 66/158 (42%), Positives = 102/158 (65%), Gaps = 0/158 (0%)
Query 1031 YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDY 1090
++ L ++V + D + A+ + ++VNAAN +LKHGGG+A A+++A+ +Q ESDDY
Sbjct 1192 HIVLNNDVTLVFGDAIAVARATEDCILVNAANTHLKHGGGIAAAIDRASGGLVQAESDDY 1251
Query 1091 IATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ GPL VG S +L GH LA LHVVGP+ +DIQLLK Y+ FN++ ++++PL+S
Sbjct 1252 VNFYGPLNVGDSTLLKGHGLATGILHVVGPDARANQDIQLLKRCYKAFNKYPLVVSPLIS 1311
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS 1188
AGIF +P SL + V T Y+ V + +Y+ L +
Sbjct 1312 AGIFCVEPRVSLEYLLSVVHTKTYVVVNSEKVYNDLAA 1349
>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126
Score = 5612 bits (14558), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2736/4883 (56%), Positives = 3531/4883 (72%), Gaps = 77/4883 (2%)
Query 2255 SNLGMPSYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDSLDTYPSLETIQITISS 2313
S LG+ + C G Y N T+ + +C+ S+ C CL G DSL Y +L+ +Q I+S
Sbjct 2274 SYLGIRTLCDGLAVEYRN-TSFDVVDFCSNRSVLCQWCLIGQDSLTRYSALQMLQTHITS 2332
Query 2314 FKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFA--VHFISNSWLMWLIINL 2371
+ ++ E+FLAY+L+T F VL L Q FF+Y + V++ + ++++ + L
Sbjct 2333 YVLNIDWIWFALEFFLAYVLYTSSFNVLLLVVTAQYFFAYTSAFVNWRAYNYIVSGLFFL 2392
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
V P+ +VR+Y F A +++ K Y HV++GC + C++CYKRNR TRVE +TIV G +
Sbjct 2393 VTHIPLHGLVRVYNFLACLWFLRKFYSHVINGCKDTACLLCYKRNRLTRVEASTIVCGTK 2452
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R+FY+ ANGG +C HNWNCV CDT G+TFI EVA DL+ +R I PTDQS Y V
Sbjct 2453 RTFYIAANGGTSYCCKHNWNCVECDTAGVGNTFICTEVANDLTTTLRRLIKPTDQSHYYV 2512
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRAN---NTKGSLP-INVIVFDGKS 2547
DSV VK+ + L++++ G YER+ L +F NL+ L+ T +P N +++D
Sbjct 2513 DSVVVKDAVVELHYNRDGSSCYERYPLCYFTNLEKLKFKEVCKTPTGIPEHNFLIYDTND 2572
Query 2548 KCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPME 2607
+ +E+ A+SA VYYSQ++C+P+LL+D LV+ VGDS E+A+KM D+++N+F S F+V +
Sbjct 2573 RGQENLARSACVYYSQVLCKPMLLVDVNLVTTVGDSREIAIKMLDSFINSFISLFSVSRD 2632
Query 2608 KLKTLVATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDVETKDVVECLKLSHQSDIEVT 2666
KL+ L+ TA + + VL TF AAR V+SDVET VV+ L+ +H++DI++T
Sbjct 2633 KLEKLINTARDCVRRGDDFQTVLKTFTDAARGHAGVESDVETTMVVDALQYAHKNDIQLT 2692
Query 2667 GDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLR 2726
+ NNY+ Y K +++ DLG ID A +N ++ N A +WN D+M LS+ +
Sbjct 2693 TECYNNYVPGYIKPDSINTLDLGCLIDLKAASVNQTSMRNANGACVWNSGDYMKLSDSFK 2752
Query 2727 KQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVN---NWLKQLIKVTL----- 2778
+QIR A +K N+PF+LT + R N+++ K + KIV +WL ++ +T+
Sbjct 2753 RQIRIACRKCNIPFRLTTSKLRAADNILSVKFS--ATKIVGGAPSWLLRVRDLTVKGYCI 2810
Query 2779 --VFLF-VAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFD 2835
+F+F VA + + P + ++ I+ YK I+ G+ RDIA D CFANK+ F
Sbjct 2811 LTLFVFTVAVLSWFCLPSYSIATVNFNDDRILTYKVIENGIVRDIAPNDACFANKYGHFS 2870
Query 2836 TWFSQ-RGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGN 2894
WF++ GG Y N CP+ AVI G V +P T L + F+ RVF A N
Sbjct 2871 KWFNENHGGVYRNSVDCPITIAVIAGVAGARVANVPAT-LAWVGRQIVLFVSRVF-ANTN 2928
Query 2895 ICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRY 2954
+C+TP+ I Y F+ S CVL++ECT+F+DA G P+CYD VL G+ +Y ++P RY
Sbjct 2929 VCFTPTNEIPYDTFSDSGCVLSSECTLFRDAEGNLNPFCYDPTVLPGASSYADMKPHVRY 2988
Query 2955 VLMDGSI-IQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRS 3013
+ D + I+FP E ++R+ T ++YCR G+CE S AGVC+ST+G W L N Y +
Sbjct 2989 DMYDSDMYIKFPEVIFESTLRITKTLATQYCRFGSCEESAAGVCISTNGSWALYNQNYST 3048
Query 3014 LPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGE 3073
PG++CG D +++ + L QP+ +S S+ G ++ + +T YY + +RA +
Sbjct 3049 RPGIYCGDDYFDIVRRLAVSLFQPVTYFQLSTSLAMGLVLCVFLTAAFYYINKVKRALAD 3108
Query 3074 YSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFT 3133
Y+ + L++ LC L Y+ +Y Y TFYLT + +F+ HI W VMF
Sbjct 3109 YTQCAVVAVVAALLNSLCLCFIVANPLLVAPYTAMYYYATFYLTGEPAFIMHISWYVMFG 3168
Query 3134 PLVPFWITIAYIICISTKHFYWFFSNYLKRRV-VF-NGVSFSTFEEAALCTFLLNKEMYL 3191
+VP W+ +Y + + +H +W + + K+ V VF +G +F++AA F++ K+ Y+
Sbjct 3169 TVVPIWMLASYTVGVMLRHLFWVLAYFSKKHVDVFTDGKLNCSFQDAASNIFVIGKDTYV 3228
Query 3192 KLRSDVLLPLTQ--YNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVL 3249
LR+ +TQ + RYL+L+NKYKY+SGAMDT SYREA HL KAL +S +GSD+L
Sbjct 3229 ALRN----AITQDSFVRYLSLFNKYKYYSGAMDTASYREACAAHLCKALQTYSETGSDIL 3284
Query 3250 YQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTS 3309
YQPP S+TS+VLQSG KM+ PSG VE C+VQVTCG+ TLNGLWLD+ V+CPRH++C +
Sbjct 3285 YQPPNCSVTSSVLQSGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPA 3344
Query 3310 EDMLNPNYEDLLIRKSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKF 3366
+ + +PNY+ LLI K+NH+F+VQ LRV+ HSM +LKL VD ANP TP Y F
Sbjct 3345 DQLTDPNYDALLISKTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTF 3404
Query 3367 VRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMH 3426
++PG +FSVLACYNG P+GV+ +R N TIKGSFL GSCGSVG+ + ++F YMH
Sbjct 3405 STVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVLNFVYMH 3464
Query 3427 HMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRF 3486
MEL G H G+ +G YG F D+QT Q TD T+NV+AWLYAAV+NG +WF+
Sbjct 3465 QMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPT 3524
Query 3487 TTTLNDFNLVAMKYNY-EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTIL 3545
+ +N A+ + E + +D+L + +TG++V M A+++ L G G+TIL
Sbjct 3525 RVGIVTYNEWALSNQFTEFVGTQSIDML---AHRTGVSVEQMLAAIQSL-HAGFQGKTIL 3580
Query 3546 GSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFF 3605
G + LEDEFTP DV Q GV QS VKR G HWL+ T++ + + ++Q T+++++ +
Sbjct 3581 GQSTLEDEFTPDDVNMQVMGVVMQSGVKRISYGFMHWLMSTLVLAYVSVMQLTKFTMWTY 3640
Query 3606 LYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVM 3661
L+E + A M VKHKH FL LFLLP + Y N+VY P +S ++
Sbjct 3641 LFETIPTQMTPLLFGFMACVMFTVKHKHTFLSLFLLPVALCLTYANIVYEPQTLVSSTLI 3700
Query 3662 RIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKV 3721
+ WL + L D +Y S +L ++ R + L + + Y
Sbjct 3701 AVANWLTPTSVYMRTTHL-DFGLYISLSFVLAIIVRRLYRPSMSNLALALCSGVMWFYTY 3759
Query 3722 YYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIML 3781
G+ I+ I ++TS+Y+ V + LA+ I + Y P ++ ++L
Sbjct 3760 VIGDH-SSPITYLMFITTLTSDYTITVFATVNLAKFISGLVFLYAPHLGFILPEVKLVLL 3818
Query 3782 VYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLN 3841
+Y LGY CT YFG+F LLN R+ LGVYDY VSTQEFR++ GL P+NS +A LN
Sbjct 3819 IYLCLGYMCTMYFGVFSLLNLKLRVPLGVYDYSVSTQEFRFLTGNGLHAPRNSWEALILN 3878
Query 3842 IKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLA 3901
KLLG+GG PCIKVATVQSK++D+KCTSVVLL+VLQQL +ES+SK W+ CV+LHN+IL A
Sbjct 3879 FKLLGIGGTPCIKVATVQSKLTDLKCTSVVLLTVLQQLHLESNSKAWSYCVKLHNEILAA 3938
Query 3902 KDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQ 3961
D TEAFE+ V L + L+S VD++ L ++ +N + LQA +EFS L +YA TAQ
Sbjct 3939 VDPTEAFERFVCLFATLMSFSANVDLDALANDLFENSSVLQATLTEFSHLATYAELETAQ 3998
Query 3962 EAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
+Y++A+ +GD S VLK L+K++NVAK+ +++D A+ RKLE+MA+QAMT MYKQAR+ED
Sbjct 3999 SSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKLERMAEQAMTSMYKQARAED 4058
Query 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
K+AK+ SAMQTMLF M++KLDND LN +I NAR+GCVPL+I+PL + KL VVIPD + +
Sbjct 4059 KKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSIVPLCASNKLRVVIPDISVW 4118
Query 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANS-AVKL 4139
+ + +YA +LW++ + + D+++V+ +++ ++ + +L WPL++ RA+S AVKL
Sbjct 4119 NKVVNWPSVSYAGSLWDVTVINNVDNEVVKPTDV-VETNESLTWPLVIECSRASSSAVKL 4177
Query 4140 QNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKS 4199
QNNE+ P L+ M AG Q C+ +A+AYY +G R V+ LLS+ LKWA+
Sbjct 4178 QNNEIHPKGLKTMVVTAGIDQVNCSS-SAVAYYEPVQGHRMVMGLLSENAHLKWAKVEGK 4236
Query 4200 DGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATE 4259
DG I EL+PPC+F+ PKGP+++YLYF+K LNNL+RG +LG +AATVRLQAG TE
Sbjct 4237 DGF--INIELQPPCKFLIAGPKGPEIRYLYFVKNLNNLHRGQLLGHIAATVRLQAGANTE 4294
Query 4260 VPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQE 4319
+NSTVL+ AFAVD AKAY DY+ SGG P++N VKML TGTG AI+V PEA DQE
Sbjct 4295 FASNSTVLTLVAFAVDPAKAYLDYVGSGGTPLSNYVKMLAPKTGTGVAISVKPEATADQE 4354
Query 4320 SFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGY 4379
++GGAS CLYCR HI+HP+ G C K ++VQIP DPVGF LKN C VC W GY
Sbjct 4355 TYGGASVCLYCRAHIEHPDVSGVCKYKTRFVQIPAH-VRDPVGFLLKNVPCNVCQYWVGY 4413
Query 4380 GCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDK--VAG 4436
GC+CD LR + + +FLNRV G S ARL PC +G +TDVVYRAFDI N K VAG
Sbjct 4414 GCNCDALRNNTVPQSKDTNFLNRVRGSSVNARLEPCSSGLTTDVVYRAFDICNFKARVAG 4473
Query 4437 FAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKF 4496
K+ KTN CRF + D++ + +DSYF+VKRHT SNY+ E+ Y+LLKDC AVA HDFF F
Sbjct 4474 IGKYYKTNTCRFVQVDDEGHKLDSYFIVKRHTMSNYELEKRCYDLLKDCDAVAIHDFFIF 4533
Query 4497 RIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYD 4556
+D PHI RQ LT+YTM DLVYALRHFD+ NC+ LK ILV Y CC+ YF+ K W+D
Sbjct 4534 DVDKTKTPHIVRQSLTEYTMMDLVYALRHFDQNNCEVLKSILVKYGCCEQSYFDNKLWFD 4593
Query 4557 FVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQ 4616
FVENP ++ VY LGER+RQA+L TV+ CD M +G+VGVLTLDNQDLNG WYDFGDF+
Sbjct 4594 FVENPSVIGVYHKLGERIRQAMLNTVKMCDHMVKSGLVGVLTLDNQDLNGKWYDFGDFVI 4653
Query 4617 TTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFD 4676
T PG+GV +VDSYYS LMP+L++T L AE+H D D KP I+W LL+YD+T+ ++ LF+
Sbjct 4654 TQPGAGVAIVDSYYSYLMPVLSMTNCLAAETHKDCDFNKPLIEWLLLEYDYTDYKIGLFN 4713
Query 4677 RYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVST 4736
+YFK+WDQTYHPNCVNC DDRCILHCANFNVLFS V P TSFGP+VRKIFVDGVPF+VS
Sbjct 4714 KYFKHWDQTYHPNCVNCGDDRCILHCANFNVLFSMVLPNTSFGPIVRKIFVDGVPFIVSC 4773
Query 4737 GYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNN 4796
GYH++ELG+V N DVN+H RL+ KEL++YAADPAMH AS + L D RT CFSVAALT
Sbjct 4774 GYHYKELGLVMNMDVNIHRHRLALKELMMYAADPAMHIASASALWDLRTPCFSVAALTTG 4833
Query 4797 VAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMC 4856
+ FQTV+PGNFNKDFYDF VS+GFFKEGSSV LKHFFFAQDG+AAI+DY YY YNLPTM
Sbjct 4834 LTFQTVRPGNFNKDFYDFVVSRGFFKEGSSVTLKHFFFAQDGHAAITDYSYYAYNLPTMV 4893
Query 4857 DIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQ 4916
DI+Q+LF +EVVDKYFD YDGGC+NA++VIVNNLDKSAG PFNK+GKAR+YY+SMSY++Q
Sbjct 4894 DIKQMLFCMEVVDKYFDIYDGGCLNASEVIVNNLDKSAGHPFNKFGKARVYYESMSYQEQ 4953
Query 4917 DALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRG 4976
D LFA TKRNV+PTITQMNLKYAISAKNRARTVAGVSI STMTNRQ+HQK+LKS+AATRG
Sbjct 4954 DELFAVTKRNVLPTITQMNLKYAISAKNRARTVAGVSILSTMTNRQYHQKMLKSMAATRG 5013
Query 4977 ATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTT 5036
AT VIGT+KFYGGW MLKT+Y DVE+PHLMGWDYPKCDRAMPNM RI+ASL+LARKH+T
Sbjct 5014 ATCVIGTTKFYGGWDFMLKTLYKDVESPHLMGWDYPKCDRAMPNMCRILASLILARKHST 5073
Query 5037 CCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANV 5096
CC+ S RFYRLANECAQVLSE V+CGG YVKPGGTSSGDATTAYANSVFNI QA TANV
Sbjct 5074 CCTNSDRFYRLANECAQVLSEYVLCGGGYYVKPGGTSSGDATTAYANSVFNILQATTANV 5133
Query 5097 NALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVV 5156
+AL+S +GN I D+ ++++Q LY +YR D FV+++YA+L KHFSMMILSDD VV
Sbjct 5134 SALMSANGNTIIDREIKDMQFDLYINVYRKVVPDPKFVDKYYAFLNKHFSMMILSDDGVV 5193
Query 5157 CFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGD 5216
C+NS YA++G VASI+NFK LYYQNNVFMSEAKCW ET+L KGPHEFCSQHT+ +K GD
Sbjct 5194 CYNSDYAAKGYVASIQNFKETLYYQNNVFMSEAKCWVETNLEKGPHEFCSQHTLYIKDGD 5253
Query 5217 DYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLY 5276
D +LPYPDPSRIL AGCFVDDIVKTDGT+M+ER+VSLAIDAYPLTKH + EY +VF +Y
Sbjct 5254 DGYFLPYPDPSRILSAGCFVDDIVKTDGTVMMERYVSLAIDAYPLTKHDDTEYQNVFWVY 5313
Query 5277 LQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQT 5336
LQYI KL+ +LTGHMLD YSVML D+++++WE FY +Y+ T LQAVG+CV+C+SQT
Sbjct 5314 LQYIEKLYKDLTGHMLDSYSVMLCGDDSAKFWEEGFYRDLYSSPTTLQAVGSCVVCHSQT 5373
Query 5337 SLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYC 5396
SLRCG CIRRPFLCCKCCYDHVI+T+HK+VLSV+PYVCNAPGCDV+DVT+LYLGGMSYYC
Sbjct 5374 SLRCGTCIRRPFLCCKCCYDHVIATTHKMVLSVSPYVCNAPGCDVSDVTKLYLGGMSYYC 5433
Query 5397 KSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKL 5456
H+P SFPLCANG VFGLYKN C GS ++ +FN +ATCDW+++GDY LANT TE LKL
Sbjct 5434 NDHRPVCSFPLCANGLVFGLYKNMCTGSSSIMEFNRLATCDWSDSGDYTLANTTTEPLKL 5493
Query 5457 FAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSK 5516
FAAETL+ATEE K SY IAT++E++ +REL L WEVGK +PPLNRNYVFTGY +TKNSK
Sbjct 5494 FAAETLRATEEASKQSYAIATIKEIVGERELILVWEVGKSKPPLNRNYVFTGYHLTKNSK 5553
Query 5517 VQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGL 5576
VQ+GEY FE+ DY DAV Y+ +TTYKL VGD FVLTSH+V LSAPT+V QE Y++ITG+
Sbjct 5554 VQLGEYVFERIDYSDAVSYKSSTTYKLAVGDIFVLTSHSVATLSAPTIVNQERYLKITGI 5613
Query 5577 YPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHA 5636
YPT+ + +EF+++V N+QK G KY T+QGPPGTGKSHFAIGLA+YYP+ARIVYTACSHA
Sbjct 5614 YPTITVPEEFANHVVNFQKAGFSKYVTVQGPPGTGKSHFAIGLAIYYPTARIVYTACSHA 5673
Query 5637 AVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVV 5696
AVDALC KA KYL I KCSRIIPA+ARVEC+D+FKVN T QY+F TVNALPE + DI+V
Sbjct 5674 AVDALCAKAFKYLNIAKCSRIIPAKARVECYDRFKVNDTNAQYLFSTVNALPEISVDILV 5733
Query 5697 FDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTI 5756
DE+SM TNYDLS++N+R++AKH VY+GDPAQLPAPRTLLT+GTLEPE FNSV RLM +
Sbjct 5734 VDEVSMCTNYDLSIINSRVKAKHIVYVGDPAQLPAPRTLLTRGTLEPENFNSVTRLMCNL 5793
Query 5757 GPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQ 5816
GPD+FL C RCP EIV+TVSALVY+NKL A KD S QCFK+ +KG +THD SSAINRPQ
Sbjct 5794 GPDIFLSVCYRCPKEIVNTVSALVYNNKLSAKKDASGQCFKILFKGSVTHDASSAINRPQ 5853
Query 5817 IGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTET 5876
+ V+ F+ NP W KAVFISPYNSQNAVA +LGL TQTVDSSQGSEY YVIF QT +T
Sbjct 5854 LNFVKTFIAANPNWSKAVFISPYNSQNAVARSMLGLTTQTVDSSQGSEYPYVIFCQTADT 5913
Query 5877 AHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDC 5936
AH+ N+NRFNVA+TRA+ GILC+M+ + L+D L+F L + N LQ++ VTGLFKDC
Sbjct 5914 AHANNLNRFNVAVTRAQKGILCVMTSQVLFDSLEFAELSL---NNYKLQSQIVTGLFKDC 5970
Query 5937 SKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYP 5995
S+ GL P APT+LSVD K+K T+ LCV++ I ++TY R+IS MGFK++ + GYP
Sbjct 5971 SREDVGLPPAYAPTYLSVDAKYKTTDELCVNL-NITPNVTYSRVISRMGFKLDATIPGYP 6029
Query 5996 NMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNN 6055
+FITR+EAIR VR+WIGFDVEG HA+R A GTN+PLQLGFSTGVN V P G VDT
Sbjct 6030 KLFITRDEAIRQVRSWIGFDVEGAHASRNACGTNVPLQLGFSTGVNFVVQPVGVVDTEWG 6089
Query 6056 TDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGF 6115
+ + +SA+PPPG+QFKHL+PLM KG W +VR +IVQMLSDTL LSD FV WAHGF
Sbjct 6090 SMLTTISARPPPGEQFKHLVPLMNKGATWPIVRRRIVQMLSDTLDKLSDYCTFVCWAHGF 6149
Query 6116 ELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFT 6175
ELTS YF KIG E+ CC+C RRA+ FS+ +YACW HS G+DYVYNPF +DVQQWG+
Sbjct 6150 ELTSASYFCKIGKEQRCCMCSRRASTFSSPLQSYACWSHSSGYDYVYNPFFVDVQQWGYV 6209
Query 6176 GNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACR 6235
GNL +NHD YC +H AHVAS DAIMTRCLA+++CF++RVDW + YP I E K+N+ CR
Sbjct 6210 GNLATNHDRYCGIHAGAHVASSDAIMTRCLAIYDCFIERVDWDVTYPYISHEQKLNSCCR 6269
Query 6236 KVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSY 6295
V+ VV++A+L+ KF ++DIGNPK I + + VEW FYDAQP S+ K+++LFY+
Sbjct 6270 TVERNVVRSAVLSGKFDKIYDIGNPKGIPIISEP-VEWHFYDAQPLSN---KVKKLFYTD 6325
Query 6296 ATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPA 6355
+ +F DG+CLFWNCNV +YP+N++VCRFDTRV S NLPGC+GGSLYVNKHAFHTPA
Sbjct 6326 DV-AKQFEDGLCLFWNCNVSKYPSNAVVCRFDTRVHSEFNLPGCNGGSLYVNKHAFHTPA 6384
Query 6356 FDKSAFVNLKQLPFFYYSDSPCESHGK-QVVSDIDYVPLKSATCITRCNLGGAVCRHHAN 6414
+D +AF +LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT CNLGGAVCR HA
Sbjct 6385 YDINAFRDLKPLPFFYYSTTPCEVHGSGNMLEDIDYVPLKSAVCITACNLGGAVCRKHAA 6444
Query 6415 EYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEV 6474
EYR Y++AYN++ +AGF LWVYK FD YNLW+TF ++Q LEN+AFNV+ +GHF G GE+
Sbjct 6445 EYRDYMEAYNIVSAAGFRLWVYKTFDIYNLWSTFVKVQGLENIAFNVIKQGHFTGVDGEL 6504
Query 6475 PVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAAN 6534
PV+++N+ ++TK DV +F+N+T LP NVAFEL+AKR ++ P++ +L NL VD+ N
Sbjct 6505 PVAVVNDKIFTKNGTDDVCIFKNETALPTNVAFELYAKRAVRSHPDLNLLRNLEVDVCYN 6564
Query 6535 TVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVL 6594
V+WDY R+ +TIGVC TDI P +C FD R G ++ F + NGVL
Sbjct 6565 FVLWDYDRNNIYGTTTIGVCKYTDIDVNPNLNMC------FDIRDKGSLERFMSMPNGVL 6618
Query 6595 ITEGSVKGLQPSVGPKQASLNGVTL--IGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNL 6652
I++ +K +GPK A NG L I F YKKV+ +T++T R +
Sbjct 6619 ISDRKIKNYPCIIGPKHAYFNGAILRNIDAKQPITFYLYKKVNNEFVSFSDTFYTCGRTV 6678
Query 6653 QEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKE 6712
+F + ME DFL L D FI++Y LE YAFEH+VYGDFSH+ LGGLHLLIGL K+ ++
Sbjct 6679 NDFTALTPMEEDFLVLDSDVFIKKYSLEDYAFEHVVYGDFSHTTLGGLHLLIGLYKKMRD 6738
Query 6713 SPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKV 6772
+E+ + +TV NYFITD+ T S K VCSVIDL LDDFV IIK DL VVSKVVKV
Sbjct 6739 GHILMEEMLKDRATVHNYFITDSNTASYKAVCSVIDLRLDDFVNIIKEMDLDVVSKVVKV 6798
Query 6773 TIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSA 6832
ID T I FMLWCKDG V+TFYP+LQ++ W+PG+ MP+L+K+Q+M LE C L NY S
Sbjct 6799 PIDLTMIEFMLWCKDGKVQTFYPRLQATNDWKPGLTMPSLFKVQQMNLEPCLLANYKQSI 6858
Query 6833 TLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTL 6892
+P G+ MNVAKY QLCQYLNT TLAVP NMRVIHFGAG +KGVAPGT+VLRQWLP +
Sbjct 6859 PMPNGVHMNVAKYMQLCQYLNTCTLAVPANMRVIHFGAGCEKGVAPGTSVLRQWLPLDAV 6918
Query 6893 LVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYIC 6952
L+D+DLN+FVSDAD T+ GDC TVH + DL+ISDMYDP TK V + N +K FF Y+C
Sbjct 6919 LIDNDLNEFVSDADITIFGDCVTVHVGQQVDLLISDMYDPCTKAVGEVNQTKALFFVYLC 6978
Query 6953 GFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGK 7012
FI+ LALGGSVAIKITEHSW+ADLYK+MG FA+WT F TN NASSSE FLIG N+LG+
Sbjct 6979 NFIKNNLALGGSVAIKITEHSWSADLYKIMGRFAYWTVFCTNANASSSEGFLIGINFLGE 7038
Query 7013 PREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSL 7072
+E+IDG VMHANYIFWRN+ P+ LS+YSLFD+S+FPLKL+GT V+ LKE QIN++++SL
Sbjct 7039 LKEEIDGNVMHANYIFWRNSTPMNLSTYSLFDLSRFPLKLKGTPVLQLKESQINELVISL 7098
Query 7073 LSKGRLIIRENNRVVISSDVLVN 7095
LS+G+L+IR+N+ + +S+DVLVN
Sbjct 7099 LSQGKLLIRDNDTLNVSTDVLVN 7121
Score = 302 bits (774), Expect = 6e-80, Method: Compositional matrix adjust.
Identities = 225/771 (29%), Positives = 367/771 (48%), Gaps = 46/771 (6%)
Query 1391 VCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPL 1450
+C E A V ++ K + VD G +Y Y+++ + +I N + MP
Sbjct 1352 ICTEYSANVKFLRTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGC-PGICAMPF 1409
Query 1451 GYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGS 1510
GYVTHGL+L ++ Y+R +KVP ++S + + N + + +TPE FI ++ G
Sbjct 1410 GYVTHGLDLAQSGNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGG 1467
Query 1511 YKDWSY-SGQSTQLGI---EFLKRGDKSVYYTSNPTTFHLDGEVITFDNL---KTLLSLR 1563
Y W SG + + L +++ Y N + + F +L + L+ R
Sbjct 1468 YHSWHLVSGDLIVKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFSDLEACRAYLTSR 1527
Query 1564 EVR--TIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVL 1621
+ I+V T+D +N T +++ + T+ +Q G T+ G D++ P G++ +V
Sbjct 1528 AAQQVNIEVLVTIDGVNFRTVILNDATTFRKQLGATFYKGVDISDALPTVKMGGESLFVA 1587
Query 1622 PN-DDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
N ++ V EYY T+D +FL RY S ++WK+ +G+ S+K ++ NCY+ +
Sbjct 1588 DNLSESEEVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATI 1647
Query 1681 LTLQQI-ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHA 1739
+ + + ++KF PALQ+AY R + G+ +F ALI+AY + T D + + L A
Sbjct 1648 MMIDMLHDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKA 1707
Query 1740 NLD-SCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLV 1798
L S K V C CG + G+ A +Y G S E+ + C CG + LV
Sbjct 1708 ELTVSAKMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLV 1767
Query 1799 QQESPFVMMSAPPAQYELKHGTFTCASEYTGNY------QCGHYKHITSKETL-YCIDGA 1851
+ +P++++S E+K T T N GHY H+ K+ L Y D
Sbjct 1768 EHSTPWLLVSG---LNEVKVSTSTDPVYRAFNVFQGVETSVGHYVHVRVKDGLFYKYDSG 1824
Query 1852 LLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQP 1911
LTK+S+ K +T V+Y + YT V Y LDGV E++P L NYY KD Y+T +P
Sbjct 1825 SLTKTSDMKCKMTSVWYPKVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKP 1884
Query 1912 -IDLVPNQPYPNASFDNFKFV-CDNIKFADDL----NQLTGYK--KPASRELKVTFFPDL 1963
I P P + + N V D +D + N L G+ KP S++L + P+
Sbjct 1885 TIKYSPATILPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNE 1944
Query 1964 NGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSN 2023
+GDV+ ++ +Y P +KKG L KPI+W N + A KPN +R L+ P+ N
Sbjct 1945 DGDVLLSEFNNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDN 2004
Query 2024 SFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTE---VVGDIILKPA 2080
+ VL+ +Q + E PV E+V + ++E K V G+
Sbjct 2005 KYTVLQDNTSQLI-----EPNVPVVEDV---SITTRKLIEVKCKGLNKPFVKGNFSFVND 2056
Query 2081 NNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLATHGLAAV 2130
N + + + +G T+L A YVD N+ + + N S + L T+ + L V
Sbjct 2057 PNGVTVVDTLGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVESGDLQIV 2107
Score = 172 bits (437), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 228/972 (23%), Positives = 407/972 (42%), Gaps = 88/972 (9%)
Query 8 FNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEVLSEARQHLKD-GTCGLVEVE-KGV 60
+NEK HV ++P+ D+ L F D E ++ LK+ G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTEDMASKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETL-----GVLVPHVGEIP 115
+ L P V++ H +V +A + + TL G+ P+ +
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDHVGAAMMRTTLNVKPLGMFFPYDSSLE 139
Query 116 VAYRKVLLRKNGNKGAGGHSYGADLKS---FDLGDELGTDPYEDFQENWNTKHSSGVTRE 172
LLRKNG G D K ++ D+L DP + +N
Sbjct 140 TGEHTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSE-QLDF---IDTKRGV 228
L+++L GG VD CG +G P+ ++A+ G TL++ ++D +D+ R +
Sbjct 188 LLKKLIGGDCIP-VDQYMCGKNGKPIADYAKIVAKEGLT--TLADIEVDVKSRMDSDRFI 244
Query 229 YCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQP-- 286
+ + + W R Y QT F + + D P F + S I + P
Sbjct 245 -VLNKKLYRVVWNVTRRNVPYSKQTAFTVVSVIQCDD-KESVPEHTFTIGSQILMVSPLK 302
Query 287 RVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGT 346
K + + + Y + + + S + C+ CG +W TG+ ++ CG
Sbjct 303 ATNNKNFNLKQRLLHTFYGKEAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGA 362
Query 347 ENLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGR--T 403
+ + G +P+NA+ CP +N H+ A+ ++ K + GG+ T
Sbjct 363 NYSANDVDLQSSGLVPKNALFLANCPCANNGAC--SHNAAQVYSILDGKACVEVGGKSFT 420
Query 404 IAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEKV 459
+ FGG V++Y+GC + Y+VPRA + + + G G D ++E L+K +
Sbjct 421 LTFGGVVYAYMGCCDGTMYFVPRAKSCVS-RIGDAIFTGCTGTWDKVVETANLFLEKAQH 479
Query 460 NINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN--FKVTKGKAK 517
++N F L E ++LA S +TS F E +++++ + N F VT G
Sbjct 480 SLNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDYI 536
Query 518 KGAWNIGE----QKSILSPLYAFA--SEAARVVRSIFSRTLETAQNSVRVLQKAAITILD 571
+ A NIG +I +P AF E+ + V +I + N L I+
Sbjct 537 RDAINIGANGVCNATINAPFIAFTGLGESFKKVAAI---PWKICSNLKSALDYYCSNIMF 593
Query 572 GISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYE----KLKPV 627
+ Y + D F L + +A + V++ + + GTV L
Sbjct 594 RVFPYDIP-CDVNDFVELLLDCGKLTVA-TSYFVLRYLDEKFDTVLGTVSNACQTALSSF 651
Query 628 LDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLA 687
L+ + F+ D +++ K + V A+ + VQ +++K +
Sbjct 652 LNACVAASRATAGFISDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLDIMSKAMK 711
Query 688 LCADSIIIGGAKLKALNL-GETFVTHSKGLYRKCVKSREET-----GLLMPLKAPKEIIF 741
L ++ G KL A+ G + + G Y C+ ++ +T L++P K+ +
Sbjct 712 LLHTNVSWAGTKLSAIIYEGREALLFNSGTYF-CLSTKAKTLQDQMNLVLPGDYNKKTLG 770
Query 742 L-----EGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDT 796
+ +T+ + V + G L +PT+E + +VG V ++ + + D
Sbjct 771 ILDPVPNADTIDVTANSTVVDVVHGQL----EPTNEHGPSMIVGNYVLVSDKLFVRTDDE 826
Query 797 EKYCALAPNMMVTNNTFTLKGGAPT-KVTFGDDTVIEVQGYKSVNITFELDERIDKVL-N 854
E Y L N V + F LKGG P+ KVTFGD +EV Y+SV+IT+++ +D +L +
Sbjct 827 EFY-PLCINGKVVSTLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPVLDALLSS 885
Query 855 EKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEF 914
K + +TVE V +F V+ D V+ L P+ G D++++ Y++++ G+
Sbjct 886 SKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYVYNQDGDC 945
Query 915 KLASHMYCSFYP 926
+S+M S P
Sbjct 946 AWSSNMTFSINP 957
Score = 128 bits (322), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 71/176 (40%), Positives = 107/176 (61%), Gaps = 8/176 (5%)
Query 991 QDGSEDNQT-------TTIQTIVE-VQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKN 1042
QD + +NQ T +T VE VQP+ ++ + ++ S + + ++V +
Sbjct 1117 QDEASENQVHQVPDLQCTSETKVEIVQPRQDLRPRRLRKSKVDLSKYKHTVINNSVTLVL 1176
Query 1043 ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGS 1102
D ++ A + V+VNAAN +LKHGGG+AGA+NKA+ +Q ESD+YI+ +GPL VG S
Sbjct 1177 GDAIQIASLLPKCVLVNAANRHLKHGGGIAGAINKASGGDVQEESDEYISNSGPLHVGDS 1236
Query 1103 CVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADP 1158
+L G+ LA L VVGP+ ED LLK Y+ FN+H +++ PL+S+GIF DP
Sbjct 1237 VLLKGYGLADAILRVVGPDARNNEDAALLKRCYKTFNKHTIVVTPLISSGIFSVDP 1292
>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119
Score = 5604 bits (14538), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2741/4914 (56%), Positives = 3537/4914 (72%), Gaps = 83/4914 (2%)
Query 2230 IIWFLLLSVCLGSLIYSTAALGVLM------SNLGMPSYCTGYREGYLNSTNVTIATYCT 2283
I +L + L S + A G+L S LG+ + C G Y N T+ + +C+
Sbjct 2236 IYHLVLFNQVLSSDVMLEDATGILAIYKEVRSYLGIRTLCDGLVVEYRN-TSFDVMEFCS 2294
Query 2284 G-SIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLG 2342
S+ C CL G DSL Y +L+ +Q I+S+ ++ E+FLAY+L+T F VL
Sbjct 2295 NRSVLCQWCLIGQDSLTRYSALQMLQTHITSYVLNIDWIWFALEFFLAYVLYTSSFNVLL 2354
Query 2343 LAAIMQLFFSYFA--VHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
L Q FF+Y + V++ + ++++ + LV P+ +VR+Y F A +++ K Y HV
Sbjct 2355 LVVTAQYFFAYTSAFVNWRAYNYIVSGLFFLVTHIPLHGLVRVYNFLACLWFLRKFYSHV 2414
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
++GC + C++CYKRNR TRVE +TIV G +R+FY+ ANGG +C HNWNCV CDT
Sbjct 2415 INGCKDTACLLCYKRNRLTRVEASTIVCGTKRTFYIAANGGTSYCCKHNWNCVECDTAGV 2474
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G+TFI EVA DL+ +R I PTDQS Y VDSV VK+ + L++++ G YER+ L +
Sbjct 2475 GNTFICTEVANDLTTTLRRLIKPTDQSHYYVDSVVVKDAVVELHYNRDGSSCYERYPLCY 2534
Query 2521 FVNLDNLRAN---NTKGSLP-INVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQAL 2576
F NL+ L+ T +P N +++D + +E+ A+SA VYYSQ++C+P+LL+D L
Sbjct 2535 FTNLEKLKFKEVCKTPTGIPEHNFLIYDTNDRGQENLARSACVYYSQVLCKPMLLVDVNL 2594
Query 2577 VSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISA 2636
V+ VGDS E+A+KM D+++N+F S F+V +KL+ L+ TA + + NVL TF A
Sbjct 2595 VTTVGDSREIAIKMLDSFINSFISLFSVSRDKLEKLINTARDCVRRGDDFQNVLKTFTDA 2654
Query 2637 AR-QGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCS 2695
AR V+SDVET VV+ L+ +H++DI++T + NNY+ Y K +++ DLG ID
Sbjct 2655 ARGHAGVESDVETTMVVDALQYAHKNDIQLTTECYNNYVPGYIKPDSINTLDLGCLIDLK 2714
Query 2696 ARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVT 2755
A +N ++ N A +WN D+M LS+ ++QIR A +K N+PF+LT + R N+++
Sbjct 2715 AASVNQTSMRNANGACVWNSGDYMKLSDSFKRQIRIACRKCNIPFRLTTSKLRAADNILS 2774
Query 2756 TKIALKGGKIVN---NWLKQLIKVTL-------VFLF-VAAIFYLITPVHVMSKHTDFSS 2804
K + KIV +WL ++ +T+ +F+F VA + + P + ++
Sbjct 2775 VKFS--ATKIVGGAPSWLLRVRDLTVKGYCILTLFVFTVAVLSWFCLPSYSIATVNFNDD 2832
Query 2805 EIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQ-RGGSYTNDKACPLIAAVITREVG 2863
I+ YK I+ G+ RDIA D CFANK+ F WF++ GG Y N CP+ AVI G
Sbjct 2833 RILTYKVIENGIVRDIAPNDVCFANKYGHFSKWFNENHGGVYRNSMDCPITIAVIAGVAG 2892
Query 2864 FVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFK 2923
V +P L + F+ RVF A N+C+TP I Y F+ S CVL++ECT+F+
Sbjct 2893 ARVANVPAN-LAWVGKQIVLFVSRVF-ANTNVCFTPINEIPYDTFSDSGCVLSSECTLFR 2950
Query 2924 DASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSI-IQFPNTYLEGSVRVVTTFDSE 2982
DA G P+CYD VL G+ +Y ++P RY + D + I+FP +E ++R+ T ++
Sbjct 2951 DAEGNLNPFCYDPTVLPGASSYADMKPHVRYDMYDSDMYIKFPEVIVESTLRITKTLATQ 3010
Query 2983 YCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALD 3042
YCR G+CE S AGVC+ST+G W L N Y + PG++CG D +++ + L QP+
Sbjct 3011 YCRFGSCEESAAGVCISTNGSWALYNQNYSTRPGIYCGDDYFDIVRRLAISLFQPVTYFQ 3070
Query 3043 ISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLP 3102
+S S+ G ++ + +T YY + +RA +Y+ + L++ LC L
Sbjct 3071 LSTSLAMGLVLCVFLTAAFYYINKVKRALADYTQCAVVAVVAALLNSLCLCFIVANPLLV 3130
Query 3103 GVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLK 3162
Y+ +Y Y TFYLT + +F+ HI W VMF +VP W+ +Y + + +H +W + + K
Sbjct 3131 APYTAMYYYATFYLTGEPAFIMHISWYVMFGAVVPIWMLASYTVGVMLRHLFWVLAYFSK 3190
Query 3163 RRV-VF-NGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQ--YNRYLALYNKYKYFS 3218
+ V VF +G +F++AA F++ K+ Y+ LR+ +TQ + RYL+L+NKYKY+S
Sbjct 3191 KHVDVFTDGKLNCSFQDAASNIFVIGKDTYVALRN----AITQDSFVRYLSLFNKYKYYS 3246
Query 3219 GAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEG 3278
GAMDT SYREA HL KAL +S +GSD+LYQPP S+TS+VLQSG KM+ PSG VE
Sbjct 3247 GAMDTASYREACAAHLCKALQTYSETGSDILYQPPNCSVTSSVLQSGLVKMSAPSGAVEN 3306
Query 3279 CMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQ---AGN 3335
C+VQVTCG+ TLNGLWLD+ V+CPRH++C ++ + +PNY+ LLI K+NH+F+VQ
Sbjct 3307 CIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLISKTNHSFIVQKHIGAQ 3366
Query 3336 VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRP 3395
LRV+ HSM +LKL VD ANP TP Y F ++PG +FSVLACYNG P+GV+ +R
Sbjct 3367 ANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRH 3426
Query 3396 NFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQ 3455
N TIKGSFL GSCGSVG+ + ++F YMH MEL G H G+ +G YG F D+QT Q
Sbjct 3427 NSTIKGSFLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQ 3486
Query 3456 AAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY-EPLTQDHVDILG 3514
TD T+NV+AWLYAAV+NG +WF+ + +N A+ + E + +D+L
Sbjct 3487 LQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVGTQSIDML- 3545
Query 3515 PLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKR 3574
+ +TG++V M A+++ L G G+TILG + LEDEFTP DV Q GV QS VKR
Sbjct 3546 --AHRTGVSVEQMLAAIQSL-HAGFQGKTILGQSTLEDEFTPDDVNMQVMGVVMQSGVKR 3602
Query 3575 TIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHA 3634
G HWL+ T + + + ++Q T+++++ +L+E ++ A M VKHKH
Sbjct 3603 ISYGFIHWLISTFVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLLGFMACVMFTVKHKHT 3662
Query 3635 FLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 3690
F+ LFLLP + Y N+VY P +S ++ + WL + D +Y S
Sbjct 3663 FMSLFLLPVALCLTYANIVYEPQTLISSTLIAVANWLTPTSVYMRTTHF-DFGLYISLSF 3721
Query 3691 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 3750
+L ++ R + L + + Y G+ I+ I ++TS+Y+ V
Sbjct 3722 VLAIIVRRLYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYTITVFA 3780
Query 3751 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 3810
+ LA+ I + Y P ++ ++L+Y LGY CT YFG+F LLN R+ LGV
Sbjct 3781 TVNLAKFISGLVFFYAPHLGFILPEVKLVLLIYLGLGYMCTMYFGVFSLLNLKLRVPLGV 3840
Query 3811 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSV 3870
YDY VSTQEFR++ GL P+NS +A LN KLLG+GG PCIKVATVQSK++D+KCTSV
Sbjct 3841 YDYSVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQSKLTDLKCTSV 3900
Query 3871 VLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKL 3930
VLL+VLQQL +ES+SK W+ CV+LHN+IL A D TEAFE+ V L + L+S VD++ L
Sbjct 3901 VLLTVLQQLHLESNSKAWSYCVKLHNEILAAVDPTEAFERFVCLFATLMSFSANVDLDAL 3960
Query 3931 CEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKS 3989
++ +N + LQA +EFS L +YA TAQ +Y++A+ +GD S VLK L+K++NVAK+
Sbjct 3961 ANDLFENSSVLQATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKN 4020
Query 3990 EFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNII 4049
+++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I
Sbjct 4021 AYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVI 4080
Query 4050 NNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIV 4109
NAR+GCVPL+I+PL + KL VVIPD + + + + +YA +LW+I + + D+++V
Sbjct 4081 ANARNGCVPLSIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVV 4140
Query 4110 QLSEISMDNSPNLAWPLIVTALRANS-AVKLQNNELSPVALRQMSCAAGTTQTACTDDNA 4168
+ +++ ++ + +L WPL++ R++S AVKLQNNE+ P L+ M AG Q C + +A
Sbjct 4141 KPTDV-VETNESLTWPLVIECSRSSSSAVKLQNNEIHPKGLKTMVITAGVDQVNC-NSSA 4198
Query 4169 LAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL 4228
+AYY +G R V+ LLS+ LKWA+ DG I EL+PPC+F+ PKGP+++YL
Sbjct 4199 VAYYEPVQGHRMVMGLLSENAHLKWAKVEGKDGF--INIELQPPCKFLIAGPKGPEIRYL 4256
Query 4229 YFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGG 4288
YF+K LNNL+RG +LG +AATVRLQAG TE +NSTVL+ AFAVD AKAY DY+ SGG
Sbjct 4257 YFVKNLNNLHRGQLLGHIAATVRLQAGANTEFASNSTVLTLVAFAVDPAKAYLDYVGSGG 4316
Query 4289 QPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGK 4348
P++N VKML TGTG AI+V PEA DQE++GGAS CLYCR HI+HP+ G C K +
Sbjct 4317 TPLSNYVKMLAPKTGTGVAISVKPEATADQETYGGASVCLYCRAHIEHPDVSGVCKYKTR 4376
Query 4349 YVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA 4408
+VQIP DPVGF LKN C VC W GYGC+CD LR + + +FLNRV G S
Sbjct 4377 FVQIPAH-VRDPVGFLLKNVPCNVCQYWVGYGCNCDALRNNTVPQSKDTNFLNRVRGSSV 4435
Query 4409 -ARLTPCGTGTSTDVVYRAFDIYNDK--VAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVK 4465
ARL PC +G +TDVVYRAFDI N K VAG K+ KTN CRF + D++ + +DSYF+VK
Sbjct 4436 NARLEPCSSGLTTDVVYRAFDICNFKARVAGIGKYYKTNTCRFVQVDDEGHKLDSYFIVK 4495
Query 4466 RHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRH 4525
RHT SNY+ E+ Y+LLKDC AVA HDFF F +D PHI RQ LT+YTM DLVYALRH
Sbjct 4496 RHTMSNYELEKRCYDLLKDCDAVAIHDFFIFDVDKTKTPHIVRQSLTEYTMMDLVYALRH 4555
Query 4526 FDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFC 4585
FD+ NC+ LK ILV Y CC+ YF+ K W+DFVENP ++ VY LGER+RQA+L TV+ C
Sbjct 4556 FDQNNCEVLKSILVKYGCCEQSYFDNKLWFDFVENPSVIGVYHKLGERIRQAMLNTVKMC 4615
Query 4586 DAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTA 4645
D M +G+VGVLTLDNQDLNG WYDFGDF+ T PG+GV +VDSYYS LMP+L++T L A
Sbjct 4616 DHMVKSGLVGVLTLDNQDLNGKWYDFGDFVITQPGAGVAIVDSYYSYLMPVLSMTNCLAA 4675
Query 4646 ESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANF 4705
E+H D D KP I+W LL+YD+T+ ++ LF++YFKYWDQTYHPNCVNC DDRCILHCANF
Sbjct 4676 ETHKDCDFNKPLIEWPLLEYDYTDYKIGLFNKYFKYWDQTYHPNCVNCSDDRCILHCANF 4735
Query 4706 NVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLV 4765
NVLFS V P TSFGP+VRKIFVDGVPF+VS GYH++ELG+V N D N+H RL+ KEL++
Sbjct 4736 NVLFSMVLPNTSFGPIVRKIFVDGVPFIVSCGYHYKELGLVMNMDFNIHRHRLALKELMM 4795
Query 4766 YAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGS 4825
YAADPAMH AS + L D RT CFSVAALT + FQTV+PGNFNKDFYDF VS+GFFKEGS
Sbjct 4796 YAADPAMHIASASALWDLRTPCFSVAALTTGLTFQTVRPGNFNKDFYDFVVSRGFFKEGS 4855
Query 4826 SVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQV 4885
SV LKHFFFAQDG+AAI+DY YY YNLPTM DI+Q+LF +EVVDKYFD YDGGC+NA++V
Sbjct 4856 SVTLKHFFFAQDGHAAITDYSYYAYNLPTMVDIKQMLFCMEVVDKYFDIYDGGCLNASEV 4915
Query 4886 IVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNR 4945
IVNNLDKSAG PFNK+GKAR+YY+SMSY++QD LFA TKRNV+PTITQMNLKYAISAKNR
Sbjct 4916 IVNNLDKSAGHPFNKFGKARVYYESMSYQEQDELFAVTKRNVLPTITQMNLKYAISAKNR 4975
Query 4946 ARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPH 5005
ARTVAGVSI STMTNRQ+HQK+LKS+AATRGAT VIGT+KFYGGW MLKT+Y DVE+PH
Sbjct 4976 ARTVAGVSILSTMTNRQYHQKMLKSMAATRGATCVIGTTKFYGGWDFMLKTLYKDVESPH 5035
Query 5006 LMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSL 5065
LMGWDYPKCDRAMPNM RI+ASL+LARKH+TCC+ S RFYRLANECAQVLSE V+CGG
Sbjct 5036 LMGWDYPKCDRAMPNMCRILASLILARKHSTCCTNSDRFYRLANECAQVLSEYVLCGGGY 5095
Query 5066 YVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYR 5125
YVKPGGTSSGDATTAYANSVFNI QA TANV+AL+S +GN I D+ ++++Q LY +YR
Sbjct 5096 YVKPGGTSSGDATTAYANSVFNILQATTANVSALMSANGNTIIDREIKDMQFDLYINVYR 5155
Query 5126 NRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVF 5185
D FV+++YA+L KHFSMMILSDD VVC+NS YA++G VASI+NFK LYYQNNVF
Sbjct 5156 KVVPDPKFVDKYYAFLNKHFSMMILSDDGVVCYNSDYAAKGYVASIQNFKETLYYQNNVF 5215
Query 5186 MSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGT 5245
MSEAKCW ET+L KGPHEFCSQHT+ +K GDD +LPYPDPSRIL AGCFVDDIVKTDGT
Sbjct 5216 MSEAKCWVETNLEKGPHEFCSQHTLYIKDGDDGYFLPYPDPSRILSAGCFVDDIVKTDGT 5275
Query 5246 LMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTS 5305
+M+ER+VSLAIDAYPLTKH + EY +VF +YLQYI KL+ +LTGHMLD YSVML D+++
Sbjct 5276 VMMERYVSLAIDAYPLTKHDDTEYQNVFWVYLQYIEKLYKDLTGHMLDSYSVMLCGDDSA 5335
Query 5306 RYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKL 5365
++WE FY +Y+ T LQAVG+CV+C+SQTSLRCG CIRRPFLCCKCCYDHVI+T HK+
Sbjct 5336 KFWEEGFYRDLYSSPTTLQAVGSCVVCHSQTSLRCGTCIRRPFLCCKCCYDHVIATPHKM 5395
Query 5366 VLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSD 5425
VLSV+PYVCNAPGCDV+DVT+LYLGGMSYYC H+P SFPLCANG VFGLYKN C GS
Sbjct 5396 VLSVSPYVCNAPGCDVSDVTKLYLGGMSYYCNDHRPVCSFPLCANGLVFGLYKNMCTGSS 5455
Query 5426 NVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDR 5485
++ +FN +ATCDW+++GDY LANT TE LKLFAAETL+ATEE K SY IAT++E++ +R
Sbjct 5456 SIMEFNRLATCDWSDSGDYTLANTTTEPLKLFAAETLRATEEASKQSYAIATIKEIVGER 5515
Query 5486 ELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNV 5545
EL L WEVGK +PPLNRNYVFTGY +TKNSKVQ+GEY FE+ DY DAV Y+ +TTYKL V
Sbjct 5516 ELILVWEVGKSKPPLNRNYVFTGYHLTKNSKVQLGEYVFERIDYSDAVSYKSSTTYKLAV 5575
Query 5546 GDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQ 5605
GD FVLTSH+V LSAPT+V QE Y++ITG+YPT+ + +EF+++V N+QK G KY T+Q
Sbjct 5576 GDIFVLTSHSVATLSAPTIVNQERYLKITGIYPTITVPEEFANHVVNFQKAGFSKYVTVQ 5635
Query 5606 GPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVE 5665
GPPGTGKSHFAIGLA+YYP+ARIVYTACSHAAVDALCEKA KYL I KCSRIIPA+ARVE
Sbjct 5636 GPPGTGKSHFAIGLAIYYPTARIVYTACSHAAVDALCEKAFKYLNIAKCSRIIPAKARVE 5695
Query 5666 CFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGD 5725
C+D+FKVN T QY+F TVNALPE + DI+V DE+SM TNYDLS++N+R++AKH VY+GD
Sbjct 5696 CYDRFKVNDTNSQYLFSTVNALPEISVDILVVDEVSMCTNYDLSIINSRVKAKHIVYVGD 5755
Query 5726 PAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKL 5785
PAQLPAPRTLL +GTLEPE FNSV RLM +GPD+FL C RCP EIV TVSALVY+NKL
Sbjct 5756 PAQLPAPRTLLIRGTLEPENFNSVTRLMCNLGPDIFLSVCYRCPKEIVSTVSALVYNNKL 5815
Query 5786 KAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAV 5845
A KD S QCFK+ +KG +THD SSAINRPQ+ V+ F+ NP W KAVFISPYNSQNAV
Sbjct 5816 SAKKDASGQCFKILFKGSVTHDASSAINRPQLNFVKTFIAANPNWSKAVFISPYNSQNAV 5875
Query 5846 ASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
A +LGL TQTVDSSQGSEY YVIF QT +TAH+ N+NRFNVA+TRA+ GILC+M+ + L
Sbjct 5876 ARSMLGLTTQTVDSSQGSEYPYVIFCQTADTAHANNLNRFNVAVTRAQKGILCVMTSQVL 5935
Query 5906 YDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLC 5964
+D L+F L + N LQ++ VTGLFKDCS+ TGL P APT+LSVD K+K T+ LC
Sbjct 5936 FDSLEFAELSL---NNYKLQSQIVTGLFKDCSREDTGLPPAYAPTYLSVDAKYKTTDELC 5992
Query 5965 VDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRE 6024
V++ I ++TY R+IS MGFK++ + GYP +FITR+EAIR VR+W+GFDVEG HA+R
Sbjct 5993 VNL-NITPNVTYSRVISRMGFKLDATIPGYPKLFITRDEAIRQVRSWVGFDVEGAHASRN 6051
Query 6025 AVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPW 6084
A GTN+PLQLGFSTGVN V P G VDT + + +SA+PPPG+QFKHL+PLM KG W
Sbjct 6052 ACGTNVPLQLGFSTGVNFVVQPVGVVDTEWGSMLTTISARPPPGEQFKHLVPLMNKGATW 6111
Query 6085 NVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFST 6144
+VR +IVQMLSDTL LSD FV WAHGFELTS YF KIG E+ C +C RRA+ FS+
Sbjct 6112 PIVRRRIVQMLSDTLDKLSDYCTFVCWAHGFELTSASYFCKIGKEQRCSMCSRRASTFSS 6171
Query 6145 ASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRC 6204
+YACW HS G+DYVYNPF +DVQQWG+ GNL +NHD YC +H AHVAS DAIMTRC
Sbjct 6172 PLQSYACWSHSSGYDYVYNPFFVDVQQWGYVGNLATNHDRYCGIHAGAHVASSDAIMTRC 6231
Query 6205 LAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIK 6264
LA+++CF++RVDW + YP I E K+N+ CR V+ VV++A+L+ KF ++DIGNPK I
Sbjct 6232 LAIYDCFIERVDWDVTYPYISHEQKLNSCCRTVERNVVRSAVLSGKFEKIYDIGNPKGIA 6291
Query 6265 CVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVC 6324
+ + VEW FYDAQP S+ K+++LFY+ S +F DG+CLFWNCNV +YP+N++VC
Sbjct 6292 IISEP-VEWHFYDAQPLSN---KVKKLFYTDDV-SKQFEDGLCLFWNCNVSKYPSNAVVC 6346
Query 6325 RFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGK-Q 6383
RFDTRV S NLPGC+GGSLYVNKHAFHTPA+D +AF +LK LPFFYYS +PCE HG
Sbjct 6347 RFDTRVHSEFNLPGCNGGSLYVNKHAFHTPAYDINAFRDLKPLPFFYYSTTPCEVHGSGN 6406
Query 6384 VVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYN 6443
++ DIDYVPLKSA CIT CNLGGAVCR HA EYR Y++AYN++ +AGF LWVYK FD YN
Sbjct 6407 MLEDIDYVPLKSAVCITACNLGGAVCRKHAAEYRDYMEAYNIVSAAGFRLWVYKTFDIYN 6466
Query 6444 LWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPV 6503
LW+TF ++Q LEN+AFNV+ +GHF G GE+PV+++N+ ++TK DV +F+N+T LP
Sbjct 6467 LWSTFVKVQGLENIAFNVIKQGHFTGVDGELPVAVVNDKIFTKNGTDDVCIFKNETALPT 6526
Query 6504 NVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKP 6563
NVAFEL+AKR ++ P++ +L NL VD+ N V+WDY R+ +TIGVC TDI P
Sbjct 6527 NVAFELYAKRAVRSHPDLNLLRNLEVDVCYNFVLWDYDRNNIYGTTTIGVCKYTDIDVNP 6586
Query 6564 TETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IG 6621
+C FD R G ++ F + NGVLI++ +K GPK A NG L I
Sbjct 6587 NLNMC------FDIRDKGSLERFMSMPNGVLISDRKIKNYPCISGPKHAYFNGAILRNID 6640
Query 6622 EAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEG 6681
F YKKV+ +T++T R + +F + ME DFL L D FI++Y LE
Sbjct 6641 AKQPVIFYLYKKVNNEFVSFSDTFYTCGRTVGDFTVLTPMEEDFLVLDSDVFIKKYGLED 6700
Query 6682 YAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSK 6741
YAFEH+VYGDFSH+ LGGLHLLIGL K+ +E +E+ + +TV NYFITD+ T S K
Sbjct 6701 YAFEHVVYGDFSHTTLGGLHLLIGLYKKMREGHILMEEMLKDRATVHNYFITDSNTASYK 6760
Query 6742 CVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQ 6801
VCSVIDL LDDFV IIK DL VVSKVVKV ID T I FMLWC+DG V+TFYP+LQ++
Sbjct 6761 AVCSVIDLRLDDFVTIIKEMDLDVVSKVVKVPIDLTMIEFMLWCRDGKVQTFYPRLQATN 6820
Query 6802 AWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPY 6861
W+PG+ MP+L+K+Q+M LE C L NY S +P G+ MNVAKY QLCQYLNT TLAVP
Sbjct 6821 DWKPGLTMPSLFKVQQMNLEPCLLANYKQSIPMPNGVHMNVAKYMQLCQYLNTCTLAVPA 6880
Query 6862 NMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANK 6921
NMRVIHFGAG +KGVAPGT+VLRQWLP +L+D+DLN+FVSDAD T+ GDC TVH +
Sbjct 6881 NMRVIHFGAGCEKGVAPGTSVLRQWLPLDAVLIDNDLNEFVSDADITIFGDCVTVHVGQQ 6940
Query 6922 WDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKL 6981
DL+ISDMYDP TK V + N +K FF Y+C FI+ LALGGSVAIKITEHSW+ADLYK+
Sbjct 6941 VDLLISDMYDPCTKAVGEVNQTKALFFVYLCNFIKNNLALGGSVAIKITEHSWSADLYKI 7000
Query 6982 MGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYS 7041
MG FA+WT F TN NASSSE FLIG N+LG+ +E+IDG VMHANYIFWRN+ P+ LS+YS
Sbjct 7001 MGRFAYWTVFCTNANASSSEGFLIGINFLGELKEEIDGNVMHANYIFWRNSTPMNLSTYS 7060
Query 7042 LFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
LFD+S+FPLKL+GT V+ LKE QIN++++SLLS+G+L+IR+N+ + +S+DVLVN
Sbjct 7061 LFDLSRFPLKLKGTPVLQLKESQINELVISLLSQGKLLIRDNDTLNVSTDVLVN 7114
Score = 305 bits (781), Expect = 1e-80, Method: Compositional matrix adjust.
Identities = 226/771 (29%), Positives = 368/771 (48%), Gaps = 46/771 (6%)
Query 1391 VCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPL 1450
+C E A V ++ K + VD G +Y Y+++ + +I N + + MP
Sbjct 1345 ICTEYSANVKFLRTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGCS-GICAMPF 1402
Query 1451 GYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGS 1510
GYVTHGL+L ++ Y+R +KVP ++S + + N + + +TPE FI ++ G
Sbjct 1403 GYVTHGLDLAQSGNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGG 1460
Query 1511 YKDWSY-SGQSTQLGI---EFLKRGDKSVYYTSNPTTFHLDGEVITFDNL---KTLLSLR 1563
Y W SG + + L +++ Y N + + F +L + L+ R
Sbjct 1461 YHSWHLVSGDLIVKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFSDLEACRAYLTSR 1520
Query 1564 EVR--TIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVL 1621
+ I+V T+D +N T +++ + T+ +Q G T+ G D++ P G++ +V
Sbjct 1521 AAQQVNIEVLVTIDGVNFRTVILNDTTTFRKQLGATFYKGVDISDAFPTVKMGGESLFVA 1580
Query 1622 PN-DDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
N ++ +V EYY T+D +FL RY S ++WK+ +G+ S+K ++ NCY+ +
Sbjct 1581 DNLSESEKVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATI 1640
Query 1681 LTLQQI-ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHA 1739
+ + + ++KF PALQ+AY R + G+ +F ALI+AY + T D + + L A
Sbjct 1641 MMIDMLHDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKA 1700
Query 1740 NLD-SCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLV 1798
L S K V C CG + G+ A +Y G S E+ + C CG + LV
Sbjct 1701 ELTVSAKMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLV 1760
Query 1799 QQESPFVMMSAPPAQYELKHGTFTCASEYTGNY------QCGHYKHITSKETL-YCIDGA 1851
+ +P++++S E+K T T N GHY HI K+ L Y D
Sbjct 1761 EHSAPWLLVSG---LNEVKVSTSTDPIYRAFNVFQGVETSVGHYVHIRVKDGLFYKYDSG 1817
Query 1852 LLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQP 1911
LTK+S+ K +T V+Y YT V Y LDGV E++P L NYY KD Y+T +P
Sbjct 1818 SLTKTSDMKCKMTSVWYPTVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKP 1877
Query 1912 -IDLVPNQPYPNASFDNFKFV-CDNIKFADDL----NQLTGYK--KPASRELKVTFFPDL 1963
I P P + + N V D +D + N L G+ KP S++L + P+
Sbjct 1878 TIKYSPATILPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNE 1937
Query 1964 NGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSN 2023
+GDV+ ++ +Y P +KKG L KPI+W N + A KPN +R L+ P+ N
Sbjct 1938 DGDVLLSEFSNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDN 1997
Query 2024 SFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTE---VVGDIILKPA 2080
+ VL+ +Q E PV ++V P + ++E K V G+
Sbjct 1998 KYTVLQDNTSQ-----LVEHNVPVVDDV---PITTRKLIEVKCKGLNKPFVKGNFSFVND 2049
Query 2081 NNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLATHGLAAV 2130
N + + + +G T+L A YVD N+ + + N S + L T+ + L V
Sbjct 2050 PNGVTVVDTLGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVESGDLQIV 2100
Score = 250 bits (638), Expect = 4e-64, Method: Compositional matrix adjust.
Identities = 314/1301 (24%), Positives = 531/1301 (41%), Gaps = 186/1301 (14%)
Query 8 FNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEVLSEARQHLKD-GTCGLVEVE-KGV 60
+NEK HV ++P+ D+ L F D E ++ LK+ G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTDDMACKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGR-----SGETLGVLVPHVGEIP 115
+ L P V++ H +V +A + + + + LG+ P+ +
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDQVGAAMMRTTLNAKPLGMFFPYDSSLE 139
Query 116 VAYRKVLLRKNGNKGAGGHSYGADLKS---FDLGDELGTDPYEDFQENWNTKHSSGVTRE 172
LLRKNG G D K ++ D+L DP + +N
Sbjct 140 TGEYTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSE-QLDF---IDTKRGV 228
L+++L GG +D CG +G P+ ++A+ G TL++ ++D +D+ R +
Sbjct 188 LLKKLIGGDCIP-IDQYMCGKNGKPIADYAKIVAKEGLT--TLADIEVDVKSRMDSDRFI 244
Query 229 YCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRV 288
+ + + W R Y QT F I + D P F + S I + P +
Sbjct 245 -VLNKKLYRVVWNVTRRNVPYPKQTAFTIVSVVQCDD-KDSVPEHTFTIGSQILMVSP-L 301
Query 289 EKKKLDGFMGRIRSVYPVASPNECNQ---MCLSTLMKCDHCGETSWQTGDFVKATCEFCG 345
+ F + R +Y + Q + S + C+ CG +W TG+ ++ CG
Sbjct 302 KATNNKNFNLKQRLLYTFYGKDAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCG 361
Query 346 TENLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGR-- 402
+ + G +P+NA+ CP +N HS A+ +N K + GG+
Sbjct 362 ANYSANDVDLQSSGLVPRNALFLANCPCANNGAC--SHSAAQVYNILDGKACVEVGGKSF 419
Query 403 TIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEK 458
T+ FGG V++Y+GC + Y+VPRA + + + G G D ++E L+K +
Sbjct 420 TLTFGGVVYAYMGCCDGTMYFVPRAKSCVS-RIGDAIFTGCTGTWDKVVETANLFLEKAQ 478
Query 459 VNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN--FKVTKGKA 516
++N F L E ++LA S +TS F E +++++ + N F VT G
Sbjct 479 RSLNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDY 535
Query 517 KKGAWNIGEQ----KSILSPLYAFAS--EAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
+ A NIG +I +P AF E+ + V +I + N L + I+
Sbjct 536 IRDAINIGANGVCNATINAPFIAFTGLGESFKKVSAI---PWKICSNLKSALDYYSSNIM 592
Query 571 DGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEK----LKP 626
+ Y + D F L + +A + V++ + + GTV L
Sbjct 593 FRVFPYDIP-CDVSNFVELLLDCGKLTVA-TSYFVLRYLDEKFDTVLGTVSSACQTALSS 650
Query 627 VLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFL 686
L+ + F+ D +++ K + V A+ + VQ +++K +
Sbjct 651 FLNACVAASRATAGFINDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLDIMSKAM 710
Query 687 ALCADSIIIGGAKLKALNL-GETFVTHSKGLYRKCVKSREET-----GLLMPLKAPKEII 740
L ++ G KL A+ G + + G Y C+ ++ +T L++P K+ +
Sbjct 711 KLLHTNVSWAGTKLSAIIYEGREALLFNSGTYF-CLSTKAKTLQGQMNLVLPGDYNKKTL 769
Query 741 FL-----EGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKD 795
+ +T+ + V + G L+P T+E + +VG V ++ + + +D
Sbjct 770 GILDPVPNADTIDVNANSTVVDVVHGQLEP----TNEHGPSMIVGNYVLVSDKLFVRTED 825
Query 796 TEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSVNITFELDERIDKVL- 853
E Y L N V + F LKGG P+K VTFGD +EV Y+SV+IT+++ +D +L
Sbjct 826 EEFY-PLCTNGKVVSTLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPVLDALLS 884
Query 854 NEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGE 913
+ K + +TVE V +F V+ D V+ L P+ G D++++ Y++++ G+
Sbjct 885 SSKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYVYNQDGD 944
Query 914 FKLASHMYCSFYP--------------------PDEDEEEGDCEE-EEFEPSTQYEYGTE 952
+S+M S P P D+EE EE P
Sbjct 945 CAWSSNMTFSINPVEDVEEVEEFIEDDYLSDELPIADDEEAWARAVEEVMPLDDILVAEI 1004
Query 953 DDYQGKPLEFGATSA---ALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQ 1009
+ + PLE S ++ E QE DS + G D + + E
Sbjct 1005 ELEEDPPLETALESVEAEVVETAEAQEPSVESIDSTPSTSTVVGENDLSVKPMSRVAETD 1064
Query 1010 PQLEME----------LTPVV----------QTIEVNSFSGYLKLTDNVYIKNAD----- 1044
LE+E +T +V Q V+S + ++N + +D
Sbjct 1065 DVLELETAVVGGPVSDVTAIVTNDIVSVEQAQQCGVSSLPIQDEASENQVHQVSDLQGNE 1124
Query 1045 ---------IVEEAKKVKP---------------TVVVNAANVYLKHGGGVAGALNK--- 1077
IV+ + +KP TV+ N+ + L +A L K
Sbjct 1125 LLCSETKVEIVQPRQDLKPRRSRKSKVDLSKYKHTVINNSVTLVLGDAIQIASLLPKCIL 1184
Query 1078 --------------------ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHV 1117
A+ +Q ESD+YI+ NGPL VG S +L GH LA LHV
Sbjct 1185 VNAANRHLKHGGGIAGVINKASGGDVQEESDEYISNNGPLHVGDSVLLKGHGLADAILHV 1244
Query 1118 VGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADP 1158
VGP+ ED LLK Y+ FN+H +++ PL+SAGIF DP
Sbjct 1245 VGPDARNNEDAALLKRCYKAFNKHTIVVTPLISAGIFSVDP 1285
>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094
Score = 5427 bits (14077), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2760/5619 (49%), Positives = 3706/5619 (66%), Gaps = 182/5619 (3%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E +P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYNPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + I D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTI--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVD 2101
D K E+ I L K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAK-------ESKEINIIKLSGVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLT 2080
Query 2102 NSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNIV 2157
++ N LS + + T+ G+ V S+P D + KP N VV N +
Sbjct 2081 GCRYVVRTANALSMAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNKI 2138
Query 2158 TRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNY 2217
+ C N ++ + F LL + K T +A + + +F
Sbjct 2139 SACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFLT 2189
Query 2218 LKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTN 2275
K ++ II I+ L + ++I+S + +G G ++ ST
Sbjct 2190 FKWSVVARGACIIATIFLLWFNFIYANVIFS----DFYLPKIGFLPTFVGKIAQWIKSTF 2245
Query 2276 --VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAF 2321
VTI YC GSI C CL+G D LD Y +++ +Q ++ D AF
Sbjct 2246 SLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRAF 2300
Query 2322 -------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLV 2372
+V E ++Y L+T +FY L +Q+ ++ F+ ++ W + L+++L
Sbjct 2301 VDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLA 2360
Query 2373 QMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRR 2432
M P +R YI ASF ++ + HV GC+ C+ CYKRNR+ RV+C+TIV G+ R
Sbjct 2361 NMLPAHVFMRFYIIIASFIKLFILFRHVAYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIR 2420
Query 2433 SFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVD 2492
+ V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2421 YYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVT 2480
Query 2493 SVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES 2552
V + L++++ GQ+TY+ + S FV+ NL + KG ++V+V + + +++
Sbjct 2481 DVKQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVENDA--DKA 2538
Query 2553 SAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTL 2612
+ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L L
Sbjct 2539 NFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNAL 2598
Query 2613 VATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCN 2671
+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SCN
Sbjct 2599 IATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCN 2658
Query 2672 NYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRS 2731
N + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2659 NLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKK 2718
Query 2732 AAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLIT 2791
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2719 ACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFLLSLV-CFIG--LWCLM 2775
Query 2792 PVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTND 2848
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2776 PTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSNS 2834
Query 2849 KACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDF 2908
ACP++ AV+ +++G V +P +LR LHF+ SA G CYTP I Y++F
Sbjct 2835 MACPIVVAVVDQDLGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSNF 2893
Query 2909 ATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPNT 2967
S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2894 YASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGFIRFPEV 2953
Query 2968 YLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLL 3027
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L+
Sbjct 2954 LREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDLI 3013
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
+F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ +V N +++ +
Sbjct 3014 YQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWCV 3073
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIIC 3147
+F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3074 NFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYISV 3133
Query 3148 ISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRY 3207
+ + H +W F+ RR+ + S TFEE AL TF++ K+ Y KL++ L +NRY
Sbjct 3134 VVSNHAFWVFA--YCRRLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNRY 3189
Query 3208 LALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSGF 3266
L+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3190 LSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSGI 3249
Query 3267 RKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSN 3326
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R ++
Sbjct 3250 VKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVTS 3309
Query 3327 HNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPS 3386
+F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3310 SDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKPQ 3369
Query 3387 GVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYG 3446
G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+FYG
Sbjct 3370 GAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGDFYG 3429
Query 3447 PFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLT 3506
P+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3430 PYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQVK 3489
Query 3507 QDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGV 3566
D V + L++ TG+++ + A++K L +NG GR I+GS EDE TP DV +Q +G+
Sbjct 3490 SDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVYQQLAGI 3546
Query 3567 TFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAM 3626
QS R +KG W++ + ++ +W++F ++ N L + + + AM
Sbjct 3547 KLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAM 3605
Query 3627 MFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMY 3685
+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3606 LLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIY 3664
Query 3686 ASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNY 3744
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y
Sbjct 3665 GMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTY 3722
Query 3745 SGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYF 3804
+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N F
Sbjct 3723 TWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLF 3781
Query 3805 RLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSD 3864
R+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++D
Sbjct 3782 RMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLTD 3841
Query 3865 VKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGA 3924
VKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL + A
Sbjct 3842 VKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPAA 3901
Query 3925 VD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVL 3977
VD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + + L
Sbjct 3902 VDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQL 3961
Query 3978 KKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTML 4037
K+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+
Sbjct 3962 KQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMV 4021
Query 4038 RKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWE 4097
RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W+
Sbjct 4022 RKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQ 4081
Query 4098 IQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCA 4155
IQ + D+D QL+EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4082 IQTIQDSDGTNKQLNEISDDCN----WPLVIIANRHNEVSATVLQNNELMPAKLKTQVVN 4137
Query 4156 AGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRF 4215
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4138 SGPDQTCNTPTQC--YYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCKF 4194
Query 4216 VTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVD 4275
KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+VD
Sbjct 4195 TVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSVD 4254
Query 4276 AAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHID 4335
K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+YCR ++
Sbjct 4255 PKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIYCRARVE 4314
Query 4336 HPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSAD 4395
HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS D
Sbjct 4315 HPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSKD 4372
Query 4396 AQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDED 4454
+FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRFQ DE+
Sbjct 4373 T-NFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRFQRVDEN 4431
Query 4455 DNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKY 4514
+ +D +FVVKR + Y E Y +KDC VA+HDFF F ++G VPHI R+ LTKY
Sbjct 4432 GDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKDLTKY 4491
Query 4515 TMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERV 4574
TM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY LG
Sbjct 4492 TMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKLGPIF 4551
Query 4575 RQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLM 4634
+AL+ +F D + G+VG+LTLDNQDLNG WYDFGD++ PG GV + DSYYS +M
Sbjct 4552 NRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYYSYMM 4611
Query 4635 PILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCL 4694
P+LT+ AL E +V+ Y +DL++YDFT+ +L+LF++YFK+W YHPN V+C
Sbjct 4612 PMLTMCHALDCELYVNN----AYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNTVDCQ 4667
Query 4695 DDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLH 4754
DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N DV+ H
Sbjct 4668 DDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMDVDTH 4727
Query 4755 SSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDF 4814
RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+DFYDF
Sbjct 4728 RYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYDF 4787
Query 4815 AVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDC 4874
+SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+
Sbjct 4788 ILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEI 4847
Query 4875 YDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQM 4934
YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQM
Sbjct 4848 YDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQM 4907
Query 4935 NLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNML 4994
NLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML
Sbjct 4908 NLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDML 4967
Query 4995 KTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQV 5054
+ + DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS S RFYRLANECAQV
Sbjct 4968 RRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLANECAQV 5027
Query 5055 LSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRN 5114
LSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D +R
Sbjct 5028 LSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDLSIRA 5087
Query 5115 LQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNF 5174
LQ RLY +YR+ VD+ FV E+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I F
Sbjct 5088 LQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIANISAF 5147
Query 5175 KSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGC 5234
+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYPDPSRILGAGC
Sbjct 5148 QQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPDPSRILGAGC 5207
Query 5235 FVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDM 5294
FVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD
Sbjct 5208 FVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNDLGNQILDS 5267
Query 5295 YSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCC 5354
YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCC
Sbjct 5268 YSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCC 5327
Query 5355 YDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVF 5414
YDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L NG VF
Sbjct 5328 YDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVF 5387
Query 5415 GLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYG 5474
GLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK SY
Sbjct 5388 GLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFKQSYA 5447
Query 5475 IATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVV 5534
AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K + + V
Sbjct 5448 SATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELTNGVY 5507
Query 5535 YRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVAN 5592
YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F +NV N
Sbjct 5508 YRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQNNVVN 5564
Query 5593 YQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID 5652
YQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+
Sbjct 5565 YQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLNIN 5624
Query 5653 KCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVN 5712
C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+N
Sbjct 5625 DCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYELSVIN 5684
Query 5713 ARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEI 5772
AR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RCP EI
Sbjct 5685 ARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRCPKEI 5744
Query 5773 VDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRK 5832
VDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL NP W K
Sbjct 5745 VDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANPLWHK 5804
Query 5833 AVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRA 5892
AVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRA
Sbjct 5805 AVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITRA 5864
Query 5893 KVGILCIMSDRDLYDKLQFTSLEIPRRNVAT-LQAENVTGLFKDCSKVITGLHPTQAPTH 5951
K GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP AP+
Sbjct 5865 KKGILCVMSNMQLFEALQFTTLTLDKVPQAVETRVQCSTNLFKDCSKSYSGYHPAHAPSF 5924
Query 5952 LSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRA 6010
L+VD K+K G GI +TY RLIS+MGFK++ ++GY +FIT+EEA++ VRA
Sbjct 5925 LAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEAVKRVRA 5984
Query 6011 WIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQ 6070
W+GFD EG HATR+++GTN PLQLGFSTG++ V TG + F + AK PPG+Q
Sbjct 5985 WVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAKAPPGEQ 6044
Query 6071 FKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPER 6130
FKHLIPLM +G W+VVR +IVQM +D L +LSD VV V WA FELT ++YF K+G E
Sbjct 6045 FKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFAKVGREI 6104
Query 6131 TCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHG 6190
+C +C +RAT +++ + Y CW HS+ DY+YNP ++D+QQWG+ G+L SNHDLYC VH
Sbjct 6105 SCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDLYCSVHK 6164
Query 6191 NAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADK 6250
AHVAS DAIMTRCLAV++CF ++W +EYPII +EL IN +CR +Q +++KAA+L ++
Sbjct 6165 GAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKAAMLCNR 6224
Query 6251 FPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFW 6310
+ + +DIGNPKAI CV D ++KFYDAQP ++ L YS+ H D F DG+C+FW
Sbjct 6225 YTLCYDIGNPKAIACVK--DFDFKFYDAQPI---VKSVKTLLYSFEAHKDSFKDGLCMFW 6279
Query 6311 NCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFF 6370
NCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +LK +PFF
Sbjct 6280 NCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHLKPMPFF 6339
Query 6371 YYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAG 6430
YYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR YL++YN +AG
Sbjct 6340 YYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYNTATTAG 6399
Query 6431 FSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGV 6490
F+ WVYK FD YNLWNTFT+LQSLENV +N+V GH+ GQ GE+P +IIN+ V K+D
Sbjct 6400 FTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKE 6459
Query 6491 DVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHIST 6550
DV +F N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY R++ +T
Sbjct 6460 DVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNT 6519
Query 6551 IGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPK 6610
GVC TD+ L V FDGR +G ++ F+ + NGV I+ VK L GP
Sbjct 6520 YGVCMYTDLK------FIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPP 6573
Query 6611 QASLNGVTL--IGE-------AVKTQ-----FNYYKKVDGVVQQLPE------------- 6643
+A LNGV + +G+ AV+ + F+ + + Q P+
Sbjct 6574 RAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVGG 6633
Query 6644 -------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQ 6696
T FTQSR + F R+ ME DF+ L D FI++Y LE YAFEHIVYG+F+
Sbjct 6634 NDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDLFIQKYGLEDYAFEHIVYGNFNQKI 6693
Query 6697 LGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVE 6756
+GGLHLLIGL +R + S +++F+ DS++ +YFITD ++G SK VC+VID+LLDDFV
Sbjct 6694 IGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVA 6753
Query 6757 IIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQ 6816
++KS +L+ VSKVV V +D+ + FMLWC D V TFYP+LQ++ W+PG +MP LYK
Sbjct 6754 LVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSMPVLYKYL 6813
Query 6817 RMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGV 6876
+E+ L NYG TLP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGS+KGV
Sbjct 6814 NSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSEKGV 6873
Query 6877 APGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKN 6936
APG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDMYDP TKN
Sbjct 6874 APGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMYDPITKN 6933
Query 6937 VTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVN 6996
+ + N SK+GFFTYIC I+ KLALGGSVAIKITE SWNA+LYKLMG+FA+WT F TN N
Sbjct 6934 IGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTVFCTNAN 6993
Query 6997 ASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTA 7056
ASSSE FLIG NYLGKP+ +IDG VMHANY+FWRN+ +YSLFDM+KFPLKL GTA
Sbjct 6994 ASSSEGFLIGINYLGKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFPLKLAGTA 7053
Query 7057 VMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
V++L+ QINDM+ SLL KG+L++R+ N+ V D LVN
Sbjct 7054 VINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDSLVN 7092
Score = 83.2 bits (204), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 79/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFD 1425
Score = 77.0 bits (188), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 207/933 (22%), Positives = 355/933 (38%), Gaps = 164/933 (18%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E S+ L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSLDSLS-AAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F+++ I ++ S V +
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKN---IPRYASA-----VAQAFRS 709
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK + +S++ F + I + G+K+ + G + HS L +
Sbjct 710 VAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP KA ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A +VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRRVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDE 931
+ + +LFDE+GE LAS +YC+F P++D+
Sbjct 936 KLEDNSLFLFDEAGEEVLASKLYCAFTAPEDDD 968
>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094
Score = 5423 bits (14068), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2760/5619 (49%), Positives = 3705/5619 (66%), Gaps = 182/5619 (3%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + +G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGENFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + I D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTI--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVD 2101
D K E+ I L K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAK-------ESKEINIIKLSGVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLT 2080
Query 2102 NSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNIV 2157
++ N+LS + + T+ G+ V S+P D + KP N VV N +
Sbjct 2081 GCRYVVRTANDLSMAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNKI 2138
Query 2158 TRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNY 2217
+ C N ++ + F LL + K T +A + + +F
Sbjct 2139 SACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFLT 2189
Query 2218 LKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTN 2275
K ++ II I+ L + ++I+S + +G G ++ ST
Sbjct 2190 FKWSVVARGACIIATIFLLWFNFIYANVIFS----DFYLPKIGFLPTFVGKIAQWIKSTF 2245
Query 2276 --VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAF 2321
VTI YC GSI C CL+G D LD Y +++ +Q ++ D AF
Sbjct 2246 SLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRAF 2300
Query 2322 -------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLV 2372
+V E ++Y L+T +FY L +Q+ ++ F+ ++ W + L+++L
Sbjct 2301 VDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLA 2360
Query 2373 QMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRR 2432
M P +R YI ASF ++ + HV GC+ C+ CYKRNR+ RV+C+TIV G+ R
Sbjct 2361 NMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIR 2420
Query 2433 SFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVD 2492
+ V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2421 YYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVT 2480
Query 2493 SVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES 2552
V + L++++ GQ+TY+ + S FV+ NL + KG ++V+V + + +++
Sbjct 2481 DVKQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVENDA--DKA 2538
Query 2553 SAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTL 2612
+ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L L
Sbjct 2539 NFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNAL 2598
Query 2613 VATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCN 2671
+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SCN
Sbjct 2599 IATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCN 2658
Query 2672 NYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRS 2731
N + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2659 NLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKK 2718
Query 2732 AAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLIT 2791
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2719 ACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFLLSLV-CFIG--LWCLM 2775
Query 2792 PVHVMSKHTDFSSEI-IGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTND 2848
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2776 PTYTVHK-SDFQLPVYTSYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSNS 2834
Query 2849 KACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDF 2908
ACP++ AV+ +++G V +P +LR LHF+ SA G CYTP I Y++F
Sbjct 2835 MACPIVVAVVDQDLGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSNF 2893
Query 2909 ATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPNT 2967
S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2894 YASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGFIRFPEV 2953
Query 2968 YLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLL 3027
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L+
Sbjct 2954 LREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDLI 3013
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
+F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ +V N +++ +
Sbjct 3014 YQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWCV 3073
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIIC 3147
+F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3074 NFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYISV 3133
Query 3148 ISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRY 3207
+ + H +W F+ RR+ + S TFEE AL TF++ K+ Y KL++ L +NRY
Sbjct 3134 VVSNHAFWVFA--YCRRLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNRY 3189
Query 3208 LALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSGF 3266
L+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3190 LSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSGI 3249
Query 3267 RKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSN 3326
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R ++
Sbjct 3250 VKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVTS 3309
Query 3327 HNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPS 3386
+F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3310 SDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKPQ 3369
Query 3387 GVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYG 3446
G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+FYG
Sbjct 3370 GAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGDFYG 3429
Query 3447 PFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLT 3506
P+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3430 PYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQVK 3489
Query 3507 QDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGV 3566
D V + L++ TG+++ + A++K L +NG GR I+GS EDE TP DV +Q +G+
Sbjct 3490 SDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVYQQLAGI 3546
Query 3567 TFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAM 3626
QS R +KG W++ + ++ +W++F ++ N L + + + AM
Sbjct 3547 KLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAM 3605
Query 3627 MFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMY 3685
+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3606 LLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIY 3664
Query 3686 ASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNY 3744
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y
Sbjct 3665 GMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTY 3722
Query 3745 SGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYF 3804
+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N F
Sbjct 3723 TWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLF 3781
Query 3805 RLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSD 3864
R+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++D
Sbjct 3782 RMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLTD 3841
Query 3865 VKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGA 3924
VKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL + A
Sbjct 3842 VKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPAA 3901
Query 3925 VD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVL 3977
VD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + + L
Sbjct 3902 VDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQL 3961
Query 3978 KKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTML 4037
K+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+
Sbjct 3962 KQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMV 4021
Query 4038 RKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWE 4097
RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W+
Sbjct 4022 RKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQ 4081
Query 4098 IQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCA 4155
IQ + D+D QL+EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4082 IQTIQDSDGTNKQLNEISDDCN----WPLVIIANRHNEVSATVLQNNELMPAKLKTQVVN 4137
Query 4156 AGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRF 4215
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4138 SGPDQTCNTPTQC--YYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCKF 4194
Query 4216 VTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVD 4275
KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+VD
Sbjct 4195 TVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSVD 4254
Query 4276 AAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHID 4335
K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+YCR ++
Sbjct 4255 PKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIYCRARVE 4314
Query 4336 HPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSAD 4395
HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS D
Sbjct 4315 HPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSKD 4372
Query 4396 AQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDED 4454
+FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRFQ DE+
Sbjct 4373 T-NFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRFQRVDEN 4431
Query 4455 DNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKY 4514
+ +D +FVVKR + Y E Y +KDC VA+HDFF F ++G VPHI R+ LTKY
Sbjct 4432 GDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKDLTKY 4491
Query 4515 TMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERV 4574
TM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY LG
Sbjct 4492 TMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKLGPIF 4551
Query 4575 RQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLM 4634
+AL+ +F D + G+VG+LTLDNQDLNG WYDFGD++ PG GV + DSYYS +M
Sbjct 4552 NRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYYSYMM 4611
Query 4635 PILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCL 4694
P+LT+ AL E +V+ Y +DL++YDFT+ +L+LF++YFK+W YHPN V+C
Sbjct 4612 PMLTMCHALDCELYVNN----AYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNTVDCQ 4667
Query 4695 DDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLH 4754
DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N DV+ H
Sbjct 4668 DDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMDVDTH 4727
Query 4755 SSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDF 4814
RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+DFYDF
Sbjct 4728 RYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYDF 4787
Query 4815 AVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDC 4874
+SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+
Sbjct 4788 ILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEI 4847
Query 4875 YDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQM 4934
YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQM
Sbjct 4848 YDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQM 4907
Query 4935 NLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNML 4994
NLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML
Sbjct 4908 NLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDML 4967
Query 4995 KTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQV 5054
+ + DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS S RFYRLANECAQV
Sbjct 4968 RRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLANECAQV 5027
Query 5055 LSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRN 5114
LSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D +R
Sbjct 5028 LSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDLSIRA 5087
Query 5115 LQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNF 5174
LQ RLY +YR+ VD+ FV E+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I F
Sbjct 5088 LQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIANISAF 5147
Query 5175 KSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGC 5234
+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYPDPSRILGAGC
Sbjct 5148 QQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPDPSRILGAGC 5207
Query 5235 FVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDM 5294
FVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD
Sbjct 5208 FVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNDLGNQILDS 5267
Query 5295 YSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCC 5354
YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCC
Sbjct 5268 YSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCC 5327
Query 5355 YDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVF 5414
YDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L NG VF
Sbjct 5328 YDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVF 5387
Query 5415 GLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYG 5474
GLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK SY
Sbjct 5388 GLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFKQSYA 5447
Query 5475 IATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVV 5534
AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K + + V
Sbjct 5448 SATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELTNGVY 5507
Query 5535 YRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVAN 5592
YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F +NV N
Sbjct 5508 YRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQNNVVN 5564
Query 5593 YQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID 5652
YQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+
Sbjct 5565 YQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLNIN 5624
Query 5653 KCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVN 5712
C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+N
Sbjct 5625 DCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYELSVIN 5684
Query 5713 ARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEI 5772
AR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RCP EI
Sbjct 5685 ARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRCPKEI 5744
Query 5773 VDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRK 5832
VDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL NP W K
Sbjct 5745 VDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANPLWHK 5804
Query 5833 AVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRA 5892
AVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRA
Sbjct 5805 AVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITRA 5864
Query 5893 KVGILCIMSDRDLYDKLQFTSLEIPRRNVAT-LQAENVTGLFKDCSKVITGLHPTQAPTH 5951
K GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP AP+
Sbjct 5865 KKGILCVMSNMQLFEALQFTTLTLDKVPQAVETRVQCSTNLFKDCSKSYSGYHPAHAPSF 5924
Query 5952 LSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRA 6010
L+VD K+K G GI +TY RLIS+MGFK++ ++GY +FIT+EEA++ VRA
Sbjct 5925 LAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEAVKRVRA 5984
Query 6011 WIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQ 6070
W+GFD EG HATR+++GTN PLQLGFSTG++ V TG + F + AK PPG+Q
Sbjct 5985 WVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAKAPPGEQ 6044
Query 6071 FKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPER 6130
FKHLIPLM +G W+VVR +IVQM +D L +LSD VV V WA FELT ++YF K+G E
Sbjct 6045 FKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFAKVGREI 6104
Query 6131 TCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHG 6190
+C +C +RAT +++ + Y CW HS+ DY+YNP ++D+QQWG+ G+L SNHDLYC VH
Sbjct 6105 SCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDLYCSVHK 6164
Query 6191 NAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADK 6250
AHVAS DAIMTRCLAV++CF ++W +EYPII +EL IN +CR +Q +++KAA+L ++
Sbjct 6165 GAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKAAMLCNR 6224
Query 6251 FPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFW 6310
+ + +DIGNPKAI CV D ++KFYDAQP ++ L YS+ H D F DG+C+FW
Sbjct 6225 YTLCYDIGNPKAIACVK--DFDFKFYDAQPI---VKSVKTLLYSFEAHKDSFKDGLCMFW 6279
Query 6311 NCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFF 6370
NCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +LK +PFF
Sbjct 6280 NCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHLKPMPFF 6339
Query 6371 YYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAG 6430
YYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR YL++YN +AG
Sbjct 6340 YYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYNTATTAG 6399
Query 6431 FSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGV 6490
F+ WVYK FD YNLWNTFT+LQSLENV +N+V GH+ GQ GE+P +IIN+ V K+D
Sbjct 6400 FTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKE 6459
Query 6491 DVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHIST 6550
DV +F N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY R++ +T
Sbjct 6460 DVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNT 6519
Query 6551 IGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPK 6610
GVC TD+ L V FDGR +G ++ F+ + NGV I+ VK L GP
Sbjct 6520 YGVCMYTDLK------FIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPP 6573
Query 6611 QASLNGVTL--IGE-------AVKTQ-----FNYYKKVDGVVQQLPE------------- 6643
+A LNGV + +G+ AV+ + F+ + + Q P+
Sbjct 6574 RAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVGG 6633
Query 6644 -------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQ 6696
T FTQSR + F R+ ME DF+ L D FI++Y LE YAFEHIVYG+F+
Sbjct 6634 NDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDLFIQKYGLEDYAFEHIVYGNFNQKI 6693
Query 6697 LGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVE 6756
+GGLHLLIGL +R + S +++F+ DS++ +YFITD ++G SK VC+VID+LLDDFV
Sbjct 6694 IGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVA 6753
Query 6757 IIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQ 6816
++KS +L+ VSKVV V +D+ + FMLWC D V TFYP+LQ++ W+PG +MP LYK
Sbjct 6754 LVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSMPVLYKYL 6813
Query 6817 RMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGV 6876
+E+ L NYG TLP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGS+KGV
Sbjct 6814 NSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSEKGV 6873
Query 6877 APGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKN 6936
APG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDMYDP TKN
Sbjct 6874 APGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMYDPITKN 6933
Query 6937 VTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVN 6996
+ + N SK+GFFTYIC I+ KLALGGSVAIKITE SWNA+LYKLMG+FA+WT F TN N
Sbjct 6934 IGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTVFCTNAN 6993
Query 6997 ASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTA 7056
ASSSE FLIG NYLGKP+ +IDG VMHANY+FWRN+ +YSLFDM+KFPLKL GTA
Sbjct 6994 ASSSEGFLIGINYLGKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFPLKLAGTA 7053
Query 7057 VMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
V++L+ QINDM+ SLL KG+L++R+ N+ V D LVN
Sbjct 7054 VINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDSLVN 7092
Score = 83.2 bits (204), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 79/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFD 1425
Score = 77.0 bits (188), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 207/933 (22%), Positives = 355/933 (38%), Gaps = 164/933 (18%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E S+ L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSLDSLS-AAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F+++ I ++ S V +
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKN---IPRYASA-----VAQAFRS 709
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK + +S++ F + I + G+K+ + G + HS L +
Sbjct 710 VAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP KA ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A +VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRRVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVVDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDE 931
+ + +LFDE+GE LAS +YC+F P++D+
Sbjct 936 KLEDNSLFLFDEAGEEVLASKLYCAFTAPEDDD 968
>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095
Score = 5406 bits (14024), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2764/5626 (49%), Positives = 3699/5626 (66%), Gaps = 195/5626 (3%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCFKWQVVVNGKYFTFKQANNNCFVNVSCLMLQSLH 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
L F Q+A+ R+G A F AL+LA G+ D R+ + +F +L
Sbjct 1685 LTFKIVQWQEAWLEFRSGRPARFVALVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q G++AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGLDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFIGD-NVGHYVHVKCEQSYQLYDASNVKKVTDVTGKLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + + D LN G+ E K+T +P GDVV + Y +++G
Sbjct 1920 YTNFKLIGHTV--CDSLNSKLGFDSSKEFVEYKITEWPTATGDVVLANDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D + +
Sbjct 1978 ITFGKPVIWLSHEKASLNSLTY----------FNRPLLVDDNKFDVLKVDDVDDSGDSSE 2027
Query 2042 EDLKPVSE-EVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
K E +++ ++K +V +I+ + K + + D+ ++
Sbjct 2028 SGAKETKEINIIKLSGVKKPF--------KVEDSVIVNDDTSETKYVKSLSIVDVYDMWL 2079
Query 2101 DNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNI 2156
++ N LSR + + T+ G+ V S+P D + KP +N VV N
Sbjct 2080 TGCKYVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPAVN-VVKAVRNK 2137
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
+ C N ++ + F LL + K T IA + + +F
Sbjct 2138 TSACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEIASKLTCKLVALAFKNAFL 2188
Query 2217 YLKSPNFSKLINII--IWFLLLSVCLGSLIYSTAAL---GVLMSNLG-----------MP 2260
K ++ II I+ L + ++I+S L G L + +G +
Sbjct 2189 TFKWSMVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIAQWIKNTFSLV 2248
Query 2261 SYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTA 2320
+ C Y + N YC GSI C CL+G D LD Y +++ +Q ++ D A
Sbjct 2249 TICDLYSIQDVGFKN----QYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRA 2299
Query 2321 F-------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINL 2371
F +V E ++Y L+T +FY L +Q+ ++ F+ ++ W L++ L
Sbjct 2300 FVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSFRLLVAL 2359
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
M P +R YI ASF ++ + HV GC+ S C+ CYKRNR+ RV+C+TIV G+
Sbjct 2360 ANMLPAHVFMRFYIIIASFIKLFSLFKHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMI 2419
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2420 RYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTV 2479
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEE 2551
V S+ L++D+ GQ+ Y+ + S FV+ NL + K ++V+V + + ++
Sbjct 2480 TDVKQVGCSMRLFYDRDGQRIYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DK 2537
Query 2552 SSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKT 2611
++ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L
Sbjct 2538 ANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNA 2597
Query 2612 LVATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSC 2670
L+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SC
Sbjct 2598 LIATAHSSIKQGTQIYKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESC 2657
Query 2671 NNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIR 2730
NN + TY K +N+ DLG I SA+H+ VAK ++ IW+V F S + +++
Sbjct 2658 NNLVPTYLKSDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQFSSDFQHKLK 2717
Query 2731 SAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLI 2790
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2718 KACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLV-CFIG--LWCL 2774
Query 2791 TPVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTN 2847
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2775 MPTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2848 DKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTD 2907
ACP++ AVI ++ G V +P +LR LHF+ SA G CYTP I Y++
Sbjct 2834 SMACPIVVAVIDQDFGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2908 FATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPN 2966
F S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2893 FYASGCVLSSACTMFTMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRFPE 2952
Query 2967 TYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNL 3026
EG VRVV T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L
Sbjct 2953 VLREGLVRVVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3027 LTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL 3086
+ +F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ VV N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSVVFVNVIVWC 3072
Query 3087 MSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYII 3146
++F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIA 3132
Query 3147 CISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ + H +W FS R++ + S TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVFS--YCRKLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSG 3265
YL+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3266 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKS 3325
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3326 NHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSP 3385
+ +F V + L V+ + M+ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMRGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3386 SGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFY 3445
G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3446 GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3505
GP+ D Q Q D +VN LAWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPIQDYIQSVNFLAWLYAAILNNCNWFIQSDKCSVEDFNVWALSNGFSQV 3488
Query 3506 TQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSG 3565
D V + L++ TG+++ + A++K L +NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3566 VTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFA 3625
+ QS R KGT W++ + ++ +W++F ++ N F + + + A
Sbjct 3546 IKLQSKRTRLFKGTVCWIMASTFLFSCIITAFVKWTMFMYVTTNMF-SITFCALCVISLA 3604
Query 3626 MMFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
M+ VKHKH +L +++ P L T+ Y N +V ++ + WL S+ + D V+
Sbjct 3605 MLLVKHKHLYLTMYITPVLFTLLYNNYLVVYKHTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3685 YASAVVL-LILMTARTVYDD---GARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISV 3740
Y +++ ++ +T R++ D V L++V +L YK G+ L++ I + ++ S+
Sbjct 3664 YGMLLLVGMVFVTLRSINHDLFSFIMFVGRLISVFSLWYK---GSNLEEEILL--MLASL 3718
Query 3741 TSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLL 3800
Y+ M +A+ ++ V ++F ++ ++L Y F+GY +CY+GLF L+
Sbjct 3719 FGTYTWTTVLSMAVAK-VIAKWVAVNVLYFTDIPQIKIVLLCYLFIGYIISCYWGLFSLM 3777
Query 3801 NRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQS 3860
N FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QS
Sbjct 3778 NSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQS 3837
Query 3861 KMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLS 3920
K++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D + AFEK+ LL VL +
Sbjct 3838 KLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFEKLAQLLIVLFA 3897
Query 3921 MQGAVD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS- 3973
AVD I ++C++ + LQA+ SEF ++ S+ + A++ ++A +G +
Sbjct 3898 NPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARFSGSAN 3957
Query 3974 EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTML 4033
+ LK+L+K+ N+AKS ++RD A+ +KLE+MAD A+T MYK+AR DK++KV SA+QTML
Sbjct 3958 QQQLKQLEKACNIAKSAYERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTML 4017
Query 4034 FTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYAS 4093
F+M+RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA
Sbjct 4018 FSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTYAG 4077
Query 4094 ALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQ 4151
+W+IQ + D+D QL+EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4078 NVWQIQTIQDSDGTNKQLNEISDDCN----WPLVIIANRYNEVSATVLQNNELMPAKLKI 4133
Query 4152 MSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEP 4211
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+P
Sbjct 4134 QVVNSGPDQTCNTPTQC--YYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDP 4190
Query 4212 PCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCA 4271
PC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CA
Sbjct 4191 PCKFTVQDAKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCA 4250
Query 4272 FAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCR 4331
F+VD K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR
Sbjct 4251 FSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCR 4310
Query 4332 CHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPML 4391
++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +
Sbjct 4311 ARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCRVCGFWRDGSCSCVS-TDTTV 4368
Query 4392 QSADAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQE 4450
QS D +FLNRV G S ARL PC +G STDV RAFDIYN VAG LK NCCRFQ
Sbjct 4369 QSKDT-NFLNRVRGASVDARLVPCASGLSTDVQLRAFDIYNASVAGIGLHLKVNCCRFQR 4427
Query 4451 KDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQR 4510
DE+ + +D +FVVKR + Y E Y +KDC VA+HDFF F ++G VPHI R+
Sbjct 4428 VDENGDKLDQFFVVKRTDLTIYNREMKCYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKD 4487
Query 4511 LTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANL 4570
LTKYTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY L
Sbjct 4488 LTKYTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKL 4547
Query 4571 GERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYY 4630
G +AL+ +F D + G+VGVLTLDNQDLNG WYDFGD++ PG GV + DSYY
Sbjct 4548 GPIFNRALVSATEFADKLVEVGLVGVLTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYY 4607
Query 4631 SLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNC 4690
S +MP+LT+ AL E +V+ Y +DL++YDFT+ +L+LF++YFK+W YHPN
Sbjct 4608 SYIMPMLTMCHALDCELYVNN----AYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNT 4663
Query 4691 VNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQD 4750
V+C DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N D
Sbjct 4664 VDCQDDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMD 4723
Query 4751 VNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKD 4810
V+ H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+D
Sbjct 4724 VDTHRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQD 4783
Query 4811 FYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDK 4870
FYDF +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV K
Sbjct 4784 FYDFVLSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYK 4843
Query 4871 YFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPT 4930
YF+ YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT
Sbjct 4844 YFEIYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPT 4903
Query 4931 ITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGW 4990
+TQMNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW
Sbjct 4904 LTQMNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGW 4963
Query 4991 HNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANE 5050
+ML+ + DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH TCCS S RFYRLANE
Sbjct 4964 DDMLRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHETCCSQSDRFYRLANE 5023
Query 5051 CAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADK 5110
CAQVLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D
Sbjct 5024 CAQVLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDL 5083
Query 5111 YVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVAS 5170
+R LQ RLY +YR+ VD+ FV E+Y +L KHFSMMILSDD VVC+NS YAS+G +A+
Sbjct 5084 SIRALQKRLYSHVYRSDKVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIAN 5143
Query 5171 IKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRIL 5230
I F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYP+PSRIL
Sbjct 5144 ISAFQQVLYYQNNVFMSESKCWVEHDINNGPHEFCSQHTMLVKMDGDDVYLPYPNPSRIL 5203
Query 5231 GAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGH 5290
GAGCFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL YI+KL+++L
Sbjct 5204 GAGCFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLAYIKKLYNDLGNQ 5263
Query 5291 MLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLC 5350
+LD YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LC
Sbjct 5264 ILDSYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLC 5323
Query 5351 CKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCAN 5410
CKCCYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L N
Sbjct 5324 CKCCYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMN 5383
Query 5411 GQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFK 5470
G VFGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK
Sbjct 5384 GLVFGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFK 5443
Query 5471 LSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYG 5530
SY AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K +
Sbjct 5444 QSYASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELT 5503
Query 5531 DAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSS 5588
+ V YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F +
Sbjct 5504 NGVYYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQN 5560
Query 5589 NVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKY 5648
NV NYQ +GM++Y T+QGPPGTGKSH AIGLA++Y +AR+VYTA SHAAVDALCEKA K+
Sbjct 5561 NVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAVFYCTARVVYTAASHAAVDALCEKAYKF 5620
Query 5649 LPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDL 5708
L I+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+L
Sbjct 5621 LNINDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYEL 5680
Query 5709 SVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRC 5768
SV+NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RC
Sbjct 5681 SVINARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRC 5740
Query 5769 PAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNP 5828
P EIVDTVSALVY+NKLKA + S CFK++YKGV TH+ SSA+N QI ++ +FL NP
Sbjct 5741 PKEIVDTVSALVYENKLKAKNESSLLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANP 5800
Query 5829 AWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVA 5888
W KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVA
Sbjct 5801 LWHKAVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVA 5860
Query 5889 ITRAKVGILCIMSDRDLYDKLQFTSL---EIPRRNVATLQAENVTGLFKDCSKVITGLHP 5945
ITRAK GILC+MS+ L++ LQFT+L ++P+ +Q T LFKDCSK +G HP
Sbjct 5861 ITRAKKGILCVMSNMQLFEALQFTTLTLDKVPQAVETKVQCS--TNLFKDCSKSYSGYHP 5918
Query 5946 TQAPTHLSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEA 6004
AP+ L+VD K+K G GI +TY RLIS+MGFK++ ++GY +FIT+EEA
Sbjct 5919 AHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEA 5978
Query 6005 IRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAK 6064
++ VRAW+GFD EG HAT +++GTN PLQLGFSTG++ V TG + F + AK
Sbjct 5979 VKRVRAWVGFDAEGAHATLDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAK 6038
Query 6065 PPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFV 6124
PPG+QFKHLIPLM +G W+VVR +IVQM +D L +LSD VV V WA FELT ++YF
Sbjct 6039 APPGEQFKHLIPLMTRGHRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFA 6098
Query 6125 KIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDL 6184
K+G E +C +C +RAT +++ + Y CW HS+ DY+YNP ++D+QQWG+ G+L SNHDL
Sbjct 6099 KVGREISCNVCTKRATVYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDL 6158
Query 6185 YCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKA 6244
YC VH AHVAS DAIMTRCLAV++CF ++W +EYPII +EL IN +CR +Q +++KA
Sbjct 6159 YCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVILKA 6218
Query 6245 ALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTD 6304
A+L +++ + +DIGNPK I CV D ++KFYDAQP ++ L YS+ H D F D
Sbjct 6219 AMLCNRYTLCYDIGNPKGIACVK--DFDFKFYDAQPI---VKSVKTLLYSFEAHKDSFKD 6273
Query 6305 GVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNL 6364
G+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +L
Sbjct 6274 GLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFARAAFEHL 6333
Query 6365 KQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYN 6424
K +PFFYYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR YL++YN
Sbjct 6334 KPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYN 6393
Query 6425 MMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVY 6484
+AGF+ WVYK FD YNLWNTFT+LQSLENV +N+V GH+ GQ GE+P +IIN+ V
Sbjct 6394 TATTAGFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVV 6453
Query 6485 TKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDA 6544
TK+D DV +F N TT P NVA EL+AKR+++ PE+K+ NL +D+ VIWDY R++
Sbjct 6454 TKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARES 6513
Query 6545 PAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQ 6604
+T GVC TD+ L V FDGR +G + F+ + NGV I+ VK L
Sbjct 6514 IFCSNTYGVCMYTDLK------FIDKLNVLFDGRDNGAFEAFKRSNNGVYISTTKVKSLS 6567
Query 6605 PSVGPKQASLNGVTL--IGE-------AVKTQ-----FNYYKKVDGVVQQLPE------- 6643
GP +A LNGV + +G+ AV+ + F+ + + Q P+
Sbjct 6568 MIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNG 6627
Query 6644 --------------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVY 6689
T FTQSR + F R+ ME DF+ L D FI++Y LE YAFEHIVY
Sbjct 6628 KPGNVGGNDALSISTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVY 6687
Query 6690 GDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDL 6749
G+F+ +GGLHLLIGL +R + S +++F+ DS++ +YFITD ++G SK VC+VID+
Sbjct 6688 GNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDI 6747
Query 6750 LLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAM 6809
LLDDFV ++KS +L+ VSKVV V +D+ + FMLWC D V TFYP+LQ++ W+PG +M
Sbjct 6748 LLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSM 6807
Query 6810 PNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFG 6869
P LYK +E+ L NYG TLP G MMNVAKYTQLCQYLNT TLAVP NMRV+H G
Sbjct 6808 PVLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLG 6867
Query 6870 AGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDM 6929
AGS+KGVAPG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDM
Sbjct 6868 AGSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDM 6927
Query 6930 YDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWT 6989
YDP TKN+ + N SK+GFFTYIC I+ KLALGGSVAIKITE SWNA+LYKLMG+FA+WT
Sbjct 6928 YDPITKNIGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWT 6987
Query 6990 AFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFP 7049
F TN NASSSE FLIG NYL KP+ +IDG VMHANY+FWRN+ +YSLFDM+KFP
Sbjct 6988 VFCTNANASSSEGFLIGINYLCKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFP 7047
Query 7050 LKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
LKL GTAV++L+ QINDM+ SLL KG+L+IR+ N+ V D LVN
Sbjct 7048 LKLAGTAVINLRADQINDMVYSLLEKGKLLIRDTNKEVFVGDSLVN 7093
Score = 80.9 bits (198), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 79/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K VK VVVN AN ++ HGGGVA A+ A E+ + + +
Sbjct 1273 ITPNVCFVKGDIIKVSKLVKAEVVVNPANGHMVHGGGVAKAIAVAAGQQFVKETTNMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++FN ++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYVLLERVYKHFNNYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T + V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFD 1425
Score = 63.9 bits (154), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 60/242 (25%), Positives = 102/242 (42%), Gaps = 30/242 (12%)
Query 715 GLYRKCVKSRE----ETGLL----MPL------------KAPKEIIFLEGETLPTEVLTE 754
G R C+ R+ E GLL +PL KA ++ I+L+G +
Sbjct 732 GRRRICLSGRKIYEVERGLLHSSQLPLDVYDLTMPSQVQKAKQKPIYLKGSGSDFSLADS 791
Query 755 EVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFT 814
V + T L P E P V +CI + + + Y + + + +
Sbjct 792 VVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDDHVGLLDQAW 846
Query 815 LKGGAPTKVTFGDDTVIE--VQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFA 872
A +VTF + ++ + K + + +ELD + +LN C + V+ ++ EF
Sbjct 847 RVPCAGRRVTFKEQPTVKEIISMPKIIKVFYELDNDFNTILNTACGVFEVDDTVDMEEFY 906
Query 873 CVVADAVIKTLQPVSELL---TPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDE 929
VV DA+ + L P EL + L + +LFDE+GE A +YC+F P++
Sbjct 907 AVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNPLFLFDEAGEEVFAPKLYCAFTAPED 966
Query 930 DE 931
D+
Sbjct 967 DD 968
>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124
Score = 5395 bits (13994), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2773/5675 (49%), Positives = 3694/5675 (65%), Gaps = 223/5675 (4%)
Query 1549 EVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIK 1608
+V + ++ LL+ + V TVD +N + V +G+ G + DG +VTK++
Sbjct 1543 KVASVSQIRALLA----NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVR 1598
Query 1609 PHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIK 1668
H+GK F+ + A D L +Y + L K W + K
Sbjct 1599 CSAIHKGKVFFQYSGLSAADLVAVTDAFGFDEPQLLKYYNMLGMCK-WPVVVCGNYFAFK 1657
Query 1669 WADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDV 1728
++NNCY+ A L LQ + LKF+ Q+A+ R+G+ F +L+LA + E D
Sbjct 1658 QSNNNCYINVACLMLQHLSLKFHKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDS 1717
Query 1729 RETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCT 1788
+ M + + A+L VCK CG +Q KGV+AVM+ GTL KG I CT
Sbjct 1718 TDFMRVVLREADLSGATCDFEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLAKGYTIACT 1776
Query 1789 CGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCI 1848
CG + + Q PF++ S P +L A+ +TG GHY H+ K
Sbjct 1777 CGNKLV-HCTQLNVPFLICSNKPEGKKLPDDV-VAANIFTGG-SLGHYTHVKCKPKYQLY 1833
Query 1849 DGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYF 1907
D ++K SE KG TD Y +N T + K T+ LD V C E +P L YY + Y+
Sbjct 1834 DACNVSKVSEAKGNFTDCLYLKNLKQTFSSKLTTFYLDDVKCVEYNPDLSQYYCESGKYY 1893
Query 1908 TEQPIDLVPNQPYPNAS--FDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLN 1964
T +PI + + + NFK V +I A+ N G+ E K+T +P
Sbjct 1894 T-KPIIKAQFRTFEKVEGVYTNFKLVGHSI--AEKFNAKLGFDCNSPFTEYKITEWPTAT 1950
Query 1965 GDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVE 2020
GDVV Y + G KP++W H + TY +P+ C ++ PV+
Sbjct 1951 GDVVLASDDLYVSRYSGGCVTFGKPVIWLGHEEASLKSLTYFNRPSVVC-ENKFNVLPVD 2009
Query 2021 TSNSFD-------VLKSEDAQG---MDNLACEDLKPVSEEVVEN---------PTIQKDV 2061
S D VL + G A E S+ VV+ DV
Sbjct 2010 VSEPTDKGPVPAAVLVTGALSGAATAPGTAKEQKVCASDSVVDQVVSGFLSDLSGATVDV 2069
Query 2062 LECNV----KTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVL 2117
E + K +V +++ + K+ + + D+ ++ + NELSR+
Sbjct 2070 KEVKLNGVKKPIKVEDSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWMANELSRL- 2128
Query 2118 GLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNR-------------V 2164
VNS T+ Y K + K+V ++ R +
Sbjct 2129 ------------VNS---PTVREYVKWGMTKIVIPAKLVLLRDEKQEFVAPKVVKAKVIA 2173
Query 2165 CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFS 2224
C + + +FF F N+ K T +A K C A N L++ N++
Sbjct 2174 CYSAVKWFFLYCFSWIKF----NTDNKVIYTTEVAS---KLTFNLCCLAFKNALQTFNWN 2226
Query 2225 KLIN--------IIIWF-------LLLSVCLGSLIYSTAALGVLMS----NLGMPSYCTG 2265
+ ++WF +L L ++ + +G +++ G+ + C
Sbjct 2227 VVSRGFFLVATVFLLWFNFLYANVILSDFYLPNIGFFPTFVGQIVAWVKTTFGIFTLCDL 2286
Query 2266 YR---EGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLT 2319
Y+ GY +S +C GS+ C +C SG D LD Y ++ +Q + SF + ++
Sbjct 2287 YQVSDVGYRSS-------FCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRVSFDY-IS 2338
Query 2320 AFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPI 2377
F LV E + Y L+T FY L MQL ++ F+ + W + + M P
Sbjct 2339 LFKLVVELVIGYSLYTVCFYPLFGLIGMQLLTTWLPEFFMLETMHWSARFFVFVANMLPA 2398
Query 2378 SAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVY 2437
++R YI + Y ++ HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V
Sbjct 2399 FTLLRFYIVVTAMYKIFCLCRHVMYGCSRPGCLFCYKRNRSVRVKCSTVVGGTLRYYDVM 2458
Query 2438 ANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVK 2497
ANGG GFC H WNC+NC F G+TFI+ E A DLS + KRP+NPTD + Y+V V
Sbjct 2459 ANGGTGFCAKHQWNCLNCSAFGPGNTFITHEAAADLSKELKRPVNPTDSAYYLVTEVKQV 2518
Query 2498 NGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSA 2557
S+ L++++ GQ+ Y+ S S FV+++ L + KG +V+V + ++ +++ +A
Sbjct 2519 GCSMRLFYERDGQRVYDDVSASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNA 2576
Query 2558 SVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAE 2617
+V+Y+Q + +P+LL+++ L++ V+ MFD YV++ +V + L + V A
Sbjct 2577 AVFYAQSLYRPMLLVEKKLITTANTGLSVSQTMFDLYVDSLLGVLDVDRKSLTSFVNAAH 2636
Query 2618 AELAKNVSLDNVLSTFISAARQG-FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLT 2676
L + V L+ V+ TFI AR+ +DSDVETK + + + + + ++ T +SCNN + T
Sbjct 2637 NSLKEGVQLEQVMDTFIGCARRKCAIDSDVETKSITKSIMSAVNAGVDFTDESCNNLVPT 2696
Query 2677 YNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKN 2736
Y K + + DLG I +A+H+ A VAK+ N+A IW+V F LS L+ ++R A K
Sbjct 2697 YVKSDTIVAADLGVLIQNNAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKT 2756
Query 2737 NLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVM 2796
L KLT V ++TT +LKGG + + L+ L V L+ V + + P + +
Sbjct 2757 GLKIKLTYNKQEANVPILTTPFSLKGGAVFSKVLQWLFVVNLICFIV---LWALMPTYAV 2813
Query 2797 SKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLI 2854
K +K ID GV RD+ TD CFANK FD W+ G Y N +ACP++
Sbjct 2814 HKSDMQLPLYASFKVIDNGVLRDVTVTDACFANKFIQFDQWYESTFGLVYYRNSRACPVV 2873
Query 2855 AAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACV 2914
AVI +++G+ + +P +LR LHF+ F+ CYTP I Y +F S CV
Sbjct 2874 VAVIDQDIGYTLFNVPTKVLR-YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCV 2932
Query 2915 LAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSV 2973
L++ CT+ A G P PYCY ++ + Y+SL P RY L + + I+FP EG V
Sbjct 2933 LSSLCTMLAHADGTPHPYCYTEGIMHNASLYDSLAPHVRYNLANSNGYIRFPEVVSEGIV 2992
Query 2974 RVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTP 3033
R+V T YCR G CE +E GVC + + WVLNN YYR++PG FCG +A +L+ +
Sbjct 2993 RIVRTRSMTYCRVGLCEDAEEGVCFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGG 3052
Query 3034 LIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLC 3093
L++PI ++AS VAG I+AI+V YY ++ +RAFG+Y+ VV N +++ ++F +L
Sbjct 3053 LVRPIDFFALTASSVAGAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLF 3112
Query 3094 LTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHF 3153
+ VY L +Y+ Y Y T Y +++S + H+QW+VM+ ++P W I Y+ + + H
Sbjct 3113 VFQVYPTLSCLYACFYFYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHA 3172
Query 3154 YWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNK 3213
W FS R++ S TFEE +L TF++ KE Y KL++ V +NRYL+LYNK
Sbjct 3173 LWLFS--YCRKLGTEVRSDGTFEEMSLTTFMITKESYCKLKNSV--SDVAFNRYLSLYNK 3228
Query 3214 YKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFP 3272
Y+YFSG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S+T++ LQSG KM FP
Sbjct 3229 YRYFSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVFP 3288
Query 3273 SGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQ 3332
+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R + +F V
Sbjct 3289 TSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYSNLLCRVISSDFCVM 3348
Query 3333 AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCA 3392
+G + L V+ + MQ +L L V NP TPKY F ++PG+TF+VLA YNG G +
Sbjct 3349 SGRMSLTVMSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGKSQGAFHVT 3408
Query 3393 MRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQ 3452
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+ D Q
Sbjct 3409 MRSSYTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQ 3468
Query 3453 TAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDI 3512
Q D T TVNV+AWLYAA++N WF+ + +L +FN+ AM + + D V
Sbjct 3469 VVQLPVQDYTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV-- 3526
Query 3513 LGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAV 3572
L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q +GV QS
Sbjct 3527 LDALASMTGVTVEQILAAIKRLY-SGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKR 3585
Query 3573 KRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHK 3632
R +KGT W+L + L ++ +W++F ++ + L + + +FAM+ VKHK
Sbjct 3586 TRVVKGTCCWILASTLLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLVKHK 3644
Query 3633 HAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL 3691
H +L +F++P L T+ Y N +V S+ WL ++ + D V+Y VVL
Sbjct 3645 HLYLTMFIMPVLCTLFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLY--GVVL 3701
Query 3692 LILM---TARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
L+ M T R++ D ++ + +++LV Y+G L++ + ++ + S+ Y+
Sbjct 3702 LVAMVFVTMRSINHDVFSVMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW-- 3757
Query 3749 TTVMFLARG-IVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
TT++ LA ++ + ++F ++ ++L Y +GY C CY+G+ LLN FR+
Sbjct 3758 TTMLSLATAKVIAKWLAVNVLYFTDVPQVKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMP 3817
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
LGVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC
Sbjct 3818 LGVYNYKISVQELRYMNANGLRPPRNSFEALVLNFKLLGIGGVPVIEVSQIQSRLTDVKC 3877
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD- 3926
+VVLL+ LQ L + SSSKLW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3878 VNVVLLNCLQHLHIASSSKLWQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDS 3937
Query 3927 -----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKL 3980
I ++ ++ + + LQA+ SEF ++ S+ + A++ ++A A+G + + +K+L
Sbjct 3938 KCLASIEEVSDDYVRDSTVLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQL 3997
Query 3981 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4040
+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKL
Sbjct 3998 EKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKL 4057
Query 4041 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQ 4100
DN ALN+I++NA GCVPLN IP T+ L +++PD + D TYA +W IQ
Sbjct 4058 DNQALNSILDNAVKGCVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQS 4117
Query 4101 VVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGT 4158
+ DAD + QL+EI + N+ WPL++ A R N S+V LQNNEL P LR +G+
Sbjct 4118 IQDADGAVKQLNEIDV----NITWPLVIAANRHNEVSSVVLQNNELMPQKLRTQVVNSGS 4173
Query 4159 TQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTD 4218
T YYNTT G+ V A+LSD LK+ + K DG + EL+PPC+F
Sbjct 4174 DMNCNTPTQ--CYYNTTGMGKIVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQ 4230
Query 4219 TPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK 4278
KG K+KYLYF+KG N L RG V+G+L++TVRLQAG ATE +NS + S CAF+VD K
Sbjct 4231 DVKGLKIKYLYFVKGCNTLARGWVVGTLSSTVRLQAGTATEYASNSAIRSLCAFSVDPKK 4290
Query 4279 AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPN 4338
Y DY+ GG P+TNCVKMLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+
Sbjct 4291 TYLDYIQQGGAPVTNCVKMLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPD 4350
Query 4339 PKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQS 4398
G C L+GK+VQ+P DPV + L + VC VCG W+ CSC QS D +
Sbjct 4351 VDGLCKLRGKFVQVPLG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVGTGS-QFQSKDT-N 4407
Query 4399 FLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNL 4457
FLNRV G S ARL PC +G TDV RAFDI N AG + K NCCRFQ DED N
Sbjct 4408 FLNRVRGTSVNARLVPCASGLDTDVQLRAFDICNANRAGIGLYYKVNCCRFQRADEDGNT 4467
Query 4458 IDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMA 4517
+D +FV+KR Y E+ Y L K+C VA+H+FF F ++G VPHI R+ L+KYTM
Sbjct 4468 LDKFFVIKRTNLEVYNKEKECYELTKECGVVAEHEFFTFDVEGSRVPHIVRKDLSKYTML 4527
Query 4518 DLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQA 4577
DL YALRHFD +C TLKEIL+TY CD+ YF KKDWYDFVEN DI+ VY LG +A
Sbjct 4528 DLCYALRHFDRNDCSTLKEILLTYAECDESYFQKKDWYDFVENSDIINVYKKLGPIFNRA 4587
Query 4578 LLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPIL 4637
LL T +F D + AG+VGVLTLDNQDL G WYDFGDF++T PG GV V DSYYS +MP+L
Sbjct 4588 LLNTAKFADTLVEAGLVGVLTLDNQDLYGQWYDFGDFVKTVPGCGVAVADSYYSYMMPML 4647
Query 4638 TLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDR 4697
T+ AL +E ++ Y ++DL++YDFT+ +L+LF++YFKYW TYHPN C DDR
Sbjct 4648 TMCHALDSELFIN----GTYREFDLVQYDFTDFKLELFNKYFKYWSMTYHPNTCECEDDR 4703
Query 4698 CILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSR 4757
CI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H R
Sbjct 4704 CIIHCANFNILFSMVLPKTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYR 4763
Query 4758 LSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVS 4817
LS K+LL+YAADPA+H AS + LLD RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +S
Sbjct 4764 LSLKDLLLYAADPALHVASASALLDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILS 4823
Query 4818 KGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDG 4877
KG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV+KYF+ YDG
Sbjct 4824 KGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVNKYFEIYDG 4883
Query 4878 GCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLK 4937
GCI A QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLK
Sbjct 4884 GCIPATQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEVYAYTKRNVLPTLTQMNLK 4943
Query 4938 YAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTV 4997
YAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ +
Sbjct 4944 YAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRL 5003
Query 4998 YSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSE 5057
DV++P LMGWDYPKCDRAMPN+LRI++SLVLARKH +CCS + RFYRLANECAQVLSE
Sbjct 5004 IKDVDSPVLMGWDYPKCDRAMPNILRIISSLVLARKHDSCCSHTDRFYRLANECAQVLSE 5063
Query 5058 MVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQH 5117
+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ
Sbjct 5064 IVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQK 5123
Query 5118 RLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSV 5177
RLY +YR VD FVNE+Y +L KHFSMMILSDD VVC+NS +AS+G +A+I F+ V
Sbjct 5124 RLYSNVYRADHVDPAFVNEYYEFLNKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQV 5183
Query 5178 LYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVD 5237
LYYQNNVFMSEAKCW ETD+ KGPHEFCSQHTMLVK D VYLPYPDPSRILGAGCFVD
Sbjct 5184 LYYQNNVFMSEAKCWVETDIEKGPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVD 5243
Query 5238 DIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSV 5297
D++KTD L+IERFVSLAIDAYPL H N EY +VF +YL+YI+KL+++L +LD YSV
Sbjct 5244 DLLKTDSVLLIERFVSLAIDAYPLVYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSYSV 5303
Query 5298 MLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDH 5357
+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC YDH
Sbjct 5304 ILSTCDGQKFTDETFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDH 5363
Query 5358 VISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLY 5417
V+ST HK VLSV+PYVCN+PGCDV DVT+LYLGGMSYYC+ HKP SF L NG VFGLY
Sbjct 5364 VMSTDHKYVLSVSPYVCNSPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLY 5423
Query 5418 KNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIAT 5477
K +C GS + DFN IA+C WT DY+LAN CTERLKLFAAET KATEE+FK Y AT
Sbjct 5424 KQSCTGSPYIEDFNKIASCKWTEVDDYVLANECTERLKLFAAETQKATEESFKQCYASAT 5483
Query 5478 VREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRG 5537
+RE++SDREL LSWE+GK RPPLN+NYVFTGY T N K +GEY F+K + + V YR
Sbjct 5484 IREIVSDRELILSWEIGKVRPPLNKNYVFTGYHFTSNGKTVLGEYVFDKSELTNGVYYRA 5543
Query 5538 TTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQK 5595
TTTYKL+VGD F+LTSH V LSAPTLVPQE+Y +R +Y ++ + F +NV NYQ
Sbjct 5544 TTTYKLSVGDVFILTSHAVSSLSAPTLVPQENYTSIRFASVY---SVPETFQNNVPNYQH 5600
Query 5596 VGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS 5655
+GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+
Sbjct 5601 IGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLNINDCT 5660
Query 5656 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5715
RI+PA+ RV+C+DKFKVN T +YVF T+NALPE DI+V DE+SM TNY+LSV+N+R+
Sbjct 5661 RIVPAKVRVDCYDKFKVNDTTRKYVFTTINALPELVTDIIVVDEVSMLTNYELSVINSRV 5720
Query 5716 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5775
RAKHYVYIGDPAQLPAPR LL KGTLEP YFNSV +LM +GPD+FLGTC RCP EIVDT
Sbjct 5721 RAKHYVYIGDPAQLPAPRVLLNKGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDT 5780
Query 5776 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVF 5835
VSALVY NKLKA D S+ CFK++YKG TH+ SSA+N QI ++ +FL NP+W AVF
Sbjct 5781 VSALVYHNKLKAKNDNSSMCFKVYYKGQTTHESSSAVNMQQIYLISKFLKANPSWSNAVF 5840
Query 5836 ISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVG 5895
ISPYNSQN VA ++LGL TQTVDS+QGSEYD+VI++QT ETAHS NVNRFNVAITRAK G
Sbjct 5841 ISPYNSQNYVAKRVLGLQTQTVDSAQGSEYDFVIYSQTAETAHSVNVNRFNVAITRAKKG 5900
Query 5896 ILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVD 5955
ILC+MS L++ L F++L + + N LQ T LFKDCS+ G HP AP+ L+VD
Sbjct 5901 ILCVMSSMQLFESLNFSTLTLDKINNPRLQC--TTNLFKDCSRSYAGYHPAHAPSFLAVD 5958
Query 5956 TKFKTEG-LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGF 6014
K+K G L V + +TY RLIS+MGFK++ ++GY +FITR+EAIR VRAW+GF
Sbjct 5959 DKYKVGGDLAVCLNVADSAVTYSRLISLMGFKLDLTLDGYCKLFITRDEAIRRVRAWVGF 6018
Query 6015 DVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHL 6074
D EG HATR+++GTN PLQLGFSTG++ V TG + F + A+ PPG+QFKHL
Sbjct 6019 DAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGMFAERDGYVFKKAVARAPPGEQFKHL 6078
Query 6075 IPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCL 6134
+PLM +G W+VVRI+IVQMLSD L +L+D VV V WA FELT ++YF K+G E C +
Sbjct 6079 VPLMSRGQKWDVVRIRIVQMLSDHLVDLADSVVLVTWAASFELTCLRYFAKVGKEVVCSV 6138
Query 6135 CDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHV 6194
C++RATCF++ + Y CW HS DY+YNP ++D+QQWG+TG+L SNHDL C VH AHV
Sbjct 6139 CNKRATCFNSRTGYYGCWRHSYSCDYLYNPLIVDIQQWGYTGSLTSNHDLICSVHKGAHV 6198
Query 6195 ASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVL 6254
AS DAIMTRCLAVH+CF K V+W++EYPII +E+ +N +CR +Q ++ +AA+L +++ V
Sbjct 6199 ASSDAIMTRCLAVHDCFCKSVNWSLEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVC 6258
Query 6255 HDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNV 6314
+DIGNPK + CV D +KFYDA P +++ Y Y H D+F DG+C+FWNCNV
Sbjct 6259 YDIGNPKGLACVKGYD--FKFYDASPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNV 6313
Query 6315 DRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSD 6374
D+YPAN++VCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD
Sbjct 6314 DKYPANAVVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTSPFTRAAFENLKPMPFFYYSD 6373
Query 6375 SPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLW 6434
+PC +DYVPL+SATCITRCNLGGAVC HA +YR YL++YN +AGF+ W
Sbjct 6374 TPCVYMEGMESKQVDYVPLRSATCITRCNLGGAVCLKHAEDYREYLESYNTATTAGFTFW 6433
Query 6435 VYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVEL 6494
VYK FD YNLWNTFTRLQSLENV +N+VN GHFDG+ GE+P ++I V K+ DV +
Sbjct 6434 VYKTFDFYNLWNTFTRLQSLENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVV 6493
Query 6495 FENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVC 6554
F+N T P NVA EL+AKR+I+P PE+K+ NL +D+ + V+WDY +D+ ST VC
Sbjct 6494 FKNNTPFPTNVAVELFAKRSIRPHPELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVC 6553
Query 6555 SMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL 6614
TD+ L V FDGR +G ++ F+ R+GV I +K L GP++A L
Sbjct 6554 KYTDL------QCIESLNVLFDGRDNGALEAFKKCRDGVYINTTKIKSLSMIKGPQRADL 6607
Query 6615 NGVTL--IGEA-VKTQFNYYKKVDGVV-----------QQLPE----------------- 6643
NGV + +G++ V+ F + D V+ + P+
Sbjct 6608 NGVVVEKVGDSDVEFWFAMRRDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEAL 6667
Query 6644 ---TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGL 6700
T FTQSR L F PRS+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGL
Sbjct 6668 ARGTIFTQSRFLSSFAPRSEMEKDFMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGL 6727
Query 6701 HLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKS 6760
HLLIGLA+R ++S +++F+P DS++ +YFITD +GSSK VC+VIDLLLDDFV+I+KS
Sbjct 6728 HLLIGLARRQQKSNLVIQEFVPYDSSIHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKS 6787
Query 6761 QDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLL 6820
+L+ VSKVV V +D+ + FMLWC + V TFYP+LQ++ W+PG MP LYK L
Sbjct 6788 LNLNCVSKVVNVNVDFKDFQFMLWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPL 6847
Query 6821 EKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGT 6880
E+ +L NYG TLP G +MNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAPG+
Sbjct 6848 ERVNLWNYGKPITLPTGCLMNVAKYTQLCQYLNTTTLAVPANMRVLHLGAGSDKDVAPGS 6907
Query 6881 AVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKE 6940
AVLRQWLP G++LVD+D+N FVSD+ ++ G+C T+ A +WDLIISDMYDP TKN+ +
Sbjct 6908 AVLRQWLPAGSILVDNDINPFVSDSVASYYGNCITLPIACQWDLIISDMYDPLTKNIGEY 6967
Query 6941 NDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSS 7000
N SK+GFFTY+C I+ KLALGGSVAIKITE SWNA+LY LMG FA+WT F TNVNASSS
Sbjct 6968 NVSKDGFFTYLCHLIRDKLALGGSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSS 7027
Query 7001 EAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSL 7060
E FLIG N+L + R +IDG MHANY+FWRN+ +YSLFDMSKFPLK+ GTAV+SL
Sbjct 7028 EGFLIGINWLNRTRTEIDGKTMHANYLFWRNSTMWNGGAYSLFDMSKFPLKVAGTAVVSL 7087
Query 7061 KEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
K QIND++LSL+ KG+L++R+ + V D LVN
Sbjct 7088 KPDQINDLVLSLIEKGKLLVRDTRKEVFVGDSLVN 7122
Score = 71.6 bits (174), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 60/183 (33%), Positives = 83/183 (45%), Gaps = 21/183 (11%)
Query 819 APTKVTFGDD-TVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVAD 877
A KV F D V E+ + + I F LD D VL++ CS + V+ ++E VV D
Sbjct 832 AGKKVEFNDKPKVKEIPSTRKIKINFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLD 891
Query 878 AVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEG 934
AV TL P E + T + L+ + YLFDE GE +A MYCSF PD++
Sbjct 892 AVESTLSPCKEHDVIGTKVCALLNRLAEDYVYLFDEGGEEVIAPKMYCSFSAPDDE---- 947
Query 935 DCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGS 994
DC + + + + DD SAAL + QEED + Q V + D
Sbjct 948 DCVAADVVDADENQGDDADD-----------SAALV-TDTQEEDGV-AKGQVGVAESDAR 994
Query 995 EDN 997
D
Sbjct 995 LDQ 997
Score = 59.3 bits (142), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 52/154 (34%), Positives = 82/154 (53%), Gaps = 4/154 (3%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV D+++ ++V V+VN AN + HG GVAGA+ KA + E+ D +
Sbjct 1267 ITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKSFIKETADMVKN 1326
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENFNQHEVLLAPLLS 1150
G +VG +G NL K L++VGP+ +G Q L+ AY++ N+ + ++ L+S
Sbjct 1327 QGVCQVGECYESTGGNLCKTVLNIVGPDA-RGHGKQCYSFLERAYQHINKCDDVVTTLIS 1385
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
AGIF SL + V NV L +K+ +D
Sbjct 1386 AGIFSVPTDVSLTYLIGVVTKNVILVSNNKDDFD 1419
Score = 40.4 bits (93), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 84/343 (24%), Positives = 131/343 (38%), Gaps = 70/343 (20%)
Query 59 GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEI 114
GVLP+ +F + T HV +L + +G+ G +G +G VP V I
Sbjct 120 GVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCLG-NGRFIGWFVP-VTAI 177
Query 115 PVAYRK-------VLLRKNGNKG---AGGHSYGADLKSFDLGDELGTDPYEDFQENWNTK 164
P AY K +LLRK GNKG +G + +D E D E+ N K
Sbjct 178 P-AYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE---DACEEVHLNPKGK 233
Query 165 HSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDT 224
+S L++ G ++D C G + ++D CTL E +
Sbjct 234 YSRK-AYALLKGYRGVKSILFLDQYGCDYTGRLAKGLEDY------GDCTLEEMKELFP- 285
Query 225 KRGVYC-CREHEHEIAWYTERSEKS-YELQTPFEIKLAKKF-----DTFNGEC----PNF 273
V+C ++E +AW+ +R ++ LQT I+ D +G+ P
Sbjct 286 ---VWCDSLDNEVVVAWHVDRDPRAVMRLQTLATIRSIGYVGQPTEDLVDGDVVVREPAH 342
Query 274 VFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQT 333
+ N+I+K + PR+ + L Y +S E C T + CD T +
Sbjct 343 LLAANAIVKRL-PRLVETML----------YTDSSVTE---FCYKTKL-CDCGFITQFGY 387
Query 334 GDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNS 376
D C+F G++P N + CP C S
Sbjct 388 VDCCGDACDF-------------RGWVPGNMMDGFLCPGCSKS 417
>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094
Score = 5394 bits (13993), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2748/5620 (49%), Positives = 3697/5620 (66%), Gaps = 184/5620 (3%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + + D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTV--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLK-PVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
D K P +++ ++K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAKEPKEINIIKLSGVKKPF--------KVEDSVIVNDDTSEIKYVKSLSIVDVYDMWL 2079
Query 2101 DNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNI 2156
++ N LSR + + T+ G+ V S+P D + KP N VV N
Sbjct 2080 TGCRCVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNK 2137
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
++ C N ++ + F LL + K T +A + + +F
Sbjct 2138 ISACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFL 2188
Query 2217 YLKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLG-MPSYCTGYREGYLNS 2273
K ++ II I+ L + ++I+S + +G +P++ + N+
Sbjct 2189 TFKWSVVARGACIIATIFLLWFNFIYANVIFS----DFYLPKIGFLPTFVGKIAQWIKNT 2244
Query 2274 TN-VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTA 2320
+ VTI YC GSI C CL+G D LD Y +++ +Q ++ D A
Sbjct 2245 FSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRA 2299
Query 2321 F-------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINL 2371
F +V E ++Y L+T +FY L +Q+ ++ F+ ++ W + L+++L
Sbjct 2300 FVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSL 2359
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
M P +R YI ASF ++ + HV GC+ S C+ CYKRNR+ RV+C+TIV G+
Sbjct 2360 ANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMI 2419
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R + ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2420 RYYDAMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTV 2479
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEE 2551
V + L++D+ GQ+TY+ + S FV+ NL + K ++V+V + + ++
Sbjct 2480 TDVKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DK 2537
Query 2552 SSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKT 2611
++ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L
Sbjct 2538 ANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNA 2597
Query 2612 LVATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSC 2670
L+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SC
Sbjct 2598 LIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESC 2657
Query 2671 NNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIR 2730
NN + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2658 NNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLK 2717
Query 2731 SAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLI 2790
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2718 KACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLV-CFIG--LWCL 2774
Query 2791 TPVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTN 2847
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2775 MPTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2848 DKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTD 2907
ACP++ AV+ ++ G V +P +LR LHF+ SA G CYTP I Y++
Sbjct 2834 SMACPIVVAVVDQDFGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2908 FATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPN 2966
F S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2893 FYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRFPE 2952
Query 2967 TYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNL 3026
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L
Sbjct 2953 VLREGLVRIVRTRSMPYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3027 LTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL 3086
+ +F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ +V N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWC 3072
Query 3087 MSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYII 3146
++F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIS 3132
Query 3147 CISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ + H +W FS R++ + S TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVFS--YCRQLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSG 3265
YL+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3266 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKS 3325
KM P+ KVE C+V VT G TLNGLWL D VYCPRHVIC++ DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCIVSVTYGNMTLNGLWLGDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3326 NHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSP 3385
+ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3386 SGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFY 3445
G + MR ++TIKGSFL GSCGSV + I DCV F YMH +EL TG H GTD G+FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVVYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3446 GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3505
GP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQV 3488
Query 3506 TQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSG 3565
D V + L++ TG+++ + A++K L +NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKHL-KNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3566 VTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFA 3625
+ QS R +KG W++ + ++ +W++F ++ N L + + +
Sbjct 3546 IKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLT 3604
Query 3626 MMFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
M+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+
Sbjct 3605 MLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3685 YASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSN 3743
Y +++ ++ +T R++ + + V+++V Y G+ L++ I + ++ S+
Sbjct 3664 YGMLLLIGMVFVTLRSINQYLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGT 3721
Query 3744 YSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
Y+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N
Sbjct 3722 YTWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSL 3780
Query 3804 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMS 3863
FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++
Sbjct 3781 FRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLT 3840
Query 3864 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3923
DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL +
Sbjct 3841 DVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPA 3900
Query 3924 AVD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVV 3976
AVD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + +
Sbjct 3901 AVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQ 3960
Query 3977 LKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTM 4036
LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M
Sbjct 3961 LKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSM 4020
Query 4037 LRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALW 4096
+RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W
Sbjct 4021 VRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVW 4080
Query 4097 EIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSC 4154
+IQ + D+D QL EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4081 QIQTIQDSDGTNKQLHEISDDCN----WPLVIIANRHNEVSATALQNNELMPAKLKTQVV 4136
Query 4155 AAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCR 4214
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+
Sbjct 4137 NSGPDQTCNTPTQC--YYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCK 4193
Query 4215 FVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAV 4274
F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+V
Sbjct 4194 FTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSV 4253
Query 4275 DAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHI 4334
D K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR +
Sbjct 4254 DPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCRARV 4313
Query 4335 DHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA 4394
+HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS
Sbjct 4314 EHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSK 4371
Query 4395 DAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDE 4453
D +FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRFQ DE
Sbjct 4372 DT-NFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRFQRVDE 4430
Query 4454 DDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTK 4513
+ + +D +FVVKR + Y E Y +KDC VA+HDFF F ++G VPHI R+ LTK
Sbjct 4431 NGDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKDLTK 4490
Query 4514 YTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGER 4573
YTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY LG
Sbjct 4491 YTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKLGPI 4550
Query 4574 VRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLL 4633
+AL+ +F D + G+VG+LTLDNQDLNG WYDFGD++ PG GV + DSYYS +
Sbjct 4551 FNRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYYSYM 4610
Query 4634 MPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNC 4693
MP+LT+ AL E +V+ Y +DL++YDFT+ +L+LF++YFK+W YHPN V+C
Sbjct 4611 MPMLTMCHALDCELYVNN----AYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNTVDC 4666
Query 4694 LDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNL 4753
DDRCI+ CANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N DV+
Sbjct 4667 QDDRCIIRCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMDVDT 4726
Query 4754 HSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYD 4813
H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+DFYD
Sbjct 4727 HRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYD 4786
Query 4814 FAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFD 4873
F +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+
Sbjct 4787 FILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFE 4846
Query 4874 CYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQ 4933
YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQ
Sbjct 4847 IYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQ 4906
Query 4934 MNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNM 4993
MNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +M
Sbjct 4907 MNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDM 4966
Query 4994 LKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQ 5053
L+ + DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS S RFYRLANE AQ
Sbjct 4967 LRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLANEYAQ 5026
Query 5054 VLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVR 5113
VLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D +R
Sbjct 5027 VLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDLSIR 5086
Query 5114 NLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKN 5173
LQ RLY +YR+ VD+ FV E+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I
Sbjct 5087 ALQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIANISA 5146
Query 5174 FKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAG 5233
F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYPDPSRILGAG
Sbjct 5147 FQQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPDPSRILGAG 5206
Query 5234 CFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLD 5293
CFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL++EL +LD
Sbjct 5207 CFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNELGNQILD 5266
Query 5294 MYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKC 5353
YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC
Sbjct 5267 SYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKC 5326
Query 5354 CYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQV 5413
CYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L NG V
Sbjct 5327 CYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMV 5386
Query 5414 FGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSY 5473
FGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK SY
Sbjct 5387 FGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFKQSY 5446
Query 5474 GIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAV 5533
AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K + + V
Sbjct 5447 ASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELTNGV 5506
Query 5534 VYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVA 5591
YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F +NV
Sbjct 5507 YYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQNNVV 5563
Query 5592 NYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPI 5651
NYQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I
Sbjct 5564 NYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLNI 5623
Query 5652 DKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVV 5711
+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+
Sbjct 5624 NDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYELSVI 5683
Query 5712 NARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAE 5771
NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RCP E
Sbjct 5684 NARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRCPKE 5743
Query 5772 IVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWR 5831
IVDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL NP W
Sbjct 5744 IVDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANPLWH 5803
Query 5832 KAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITR 5891
KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITR
Sbjct 5804 KAVFISPYNSQNFAARRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITR 5863
Query 5892 AKVGILCIMSDRDLYDKLQFTSLEIPRRNVAT-LQAENVTGLFKDCSKVITGLHPTQAPT 5950
AK GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP AP+
Sbjct 5864 AKKGILCVMSNMQLFEALQFTTLTVDKVPQAVETRVQCSTNLFKDCSKSYSGYHPAHAPS 5923
Query 5951 HLSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVR 6009
L+VD K+K G GI +TY RL S+MGFK++ ++GY +FIT+EEA++ VR
Sbjct 5924 FLAVDDKYKATGDLAVCLGIGDSAVTYSRLTSLMGFKLDVTLDGYCKLFITKEEAVKRVR 5983
Query 6010 AWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGD 6069
AW+GFD EG HATR+++GTN PLQLGFSTG++ V TG + F + AK PPG+
Sbjct 5984 AWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAKAPPGE 6043
Query 6070 QFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPE 6129
QFKHLIPLM +G W+VVR +IVQM +D L +LSD VV V WA FELT ++YF K+G E
Sbjct 6044 QFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFAKVGRE 6103
Query 6130 RTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVH 6189
+C +C +RAT +++ + Y CW HS+ DY+YNP ++D+QQWG+ G+L SNHDLYC VH
Sbjct 6104 ISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDLYCSVH 6163
Query 6190 GNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLAD 6249
AHVAS DAIMTRCLAV++CF ++W +EYPII +EL IN +CR +Q +++KAA+L +
Sbjct 6164 KGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKAAMLCN 6223
Query 6250 KFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLF 6309
++ + +DIGNPKAI CV D ++KFYDAQP ++ L Y + H D F DG+C+F
Sbjct 6224 RYTLCYDIGNPKAIACVK--DFDFKFYDAQPIVK---SVKTLLYFFEAHKDSFKDGLCMF 6278
Query 6310 WNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPF 6369
WNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +LK +PF
Sbjct 6279 WNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHLKPMPF 6338
Query 6370 FYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISA 6429
FYYSD+PC +DYVPLKSATCITRCNL GAVC HA EYR YL++YN +A
Sbjct 6339 FYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLVGAVCLKHAEEYREYLNSYNTATTA 6398
Query 6430 GFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDG 6489
GF+ WVYK FD YNLWNTFT+LQSLENV +N+V GH+ GQ GE+P +IIN+ V K+D
Sbjct 6399 GFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDK 6458
Query 6490 VDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHIS 6549
DV +F N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY R++ +
Sbjct 6459 EDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSN 6518
Query 6550 TIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGP 6609
T GVC TD+ L V FDGR +G ++ F+ + NGV I+ VK L GP
Sbjct 6519 TYGVCMYTDLK------FIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGP 6572
Query 6610 KQASLNGVTL--IGE-------AVKTQ-----FNYYKKVDGVVQQLPE------------ 6643
+A LNGV + +G+ AV+ + F+ + + Q P+
Sbjct 6573 PRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVG 6632
Query 6644 --------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHS 6695
T FTQSR + F R+ ME DF+ L D FI++Y LE YAFEHIVYG+F+
Sbjct 6633 GNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQK 6692
Query 6696 QLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFV 6755
+GGLHLLIGL +R + S +++F+ DS++ +YFITD ++G SK VC+VID+LLDDFV
Sbjct 6693 IIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFV 6752
Query 6756 EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKM 6815
++KS +L+ VSKVV V +D+ + FMLWC D V TFY +LQ++ W+PG +MP LYK
Sbjct 6753 ALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYLRLQAASDWKPGYSMPVLYKY 6812
Query 6816 QRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKG 6875
+E+ L NYG TLP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGS+KG
Sbjct 6813 LNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSEKG 6872
Query 6876 VAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTK 6935
VAPG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDMYDP TK
Sbjct 6873 VAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMYDPITK 6932
Query 6936 NVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNV 6995
N+ + N SK+GFFTYIC I+ KLALGGSVAIKITE SWNA+LYKLMG+FA+WT F TN
Sbjct 6933 NIGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTVFCTNA 6992
Query 6996 NASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGT 7055
NASSSE FLIG NYLGKP+ +IDG VMHANY+FWRN+ +YSLFDM+KFPLKL GT
Sbjct 6993 NASSSEGFLIGINYLGKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFPLKLAGT 7052
Query 7056 AVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
AV++L+ QINDM+ SLL KG+L++R+ N+ V D +VN
Sbjct 7053 AVINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDSMVN 7092
Score = 84.0 bits (206), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T + V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFD 1425
Score = 72.0 bits (175), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 223/1004 (22%), Positives = 371/1004 (37%), Gaps = 173/1004 (17%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYAGKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E S+ L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSLDSL-GAAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F+++ I ++ S V +
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKN---IPRYASA-----VAQAFRS 709
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK + +S++ F + I + G+K+ + G + HS L +
Sbjct 710 VAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP K ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKTKQKPIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRCVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGK 958
+ + +LFDE+GE LA +YC+F P++D D EE E D
Sbjct 936 KLEDNSLFLFDEAGEEVLAPKLYCAFTAPEDD----DFLEESGVEEDDVEGEETD---LT 988
Query 959 PLEFGATSAALQPEEEQE--EDWLDDDSQQTVGQQDGSEDNQTT 1000
G A + EE E ED LDD ED Q +
Sbjct 989 VTSAGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDVQMS 1032
>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176
Score = 5381 bits (13958), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2770/5656 (49%), Positives = 3678/5656 (65%), Gaps = 220/5656 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ V TVD +N + V +G+ G + DG +VTK++ ++GK F+ +
Sbjct 1611 VDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIYKGKVFFQYSDLSEA 1670
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
+ A + D L +Y + L K W + K ++NNCY+ A L LQ +
Sbjct 1671 DLVAVKDAFGFDEPQLLKYYTMLGMCK-WPVVVCGNYFAFKQSNNNCYINVACLMLQHLS 1729
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G+ F +L+LA + E D + M + + A+L
Sbjct 1730 LKFPKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDSIDFMRVVLREADLSGATCN 1789
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
L VCK CG +Q KGV+AVM+ GTL +G I CTCG + + Q PF++
Sbjct 1790 LEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLVRGYNIACTCGSKLV-HCTQFNVPFLIC 1847
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S P +L A+ +TG GHY H+ K D + K SE KG TD
Sbjct 1848 SNTPEGRKLPDDVVA-ANIFTGG-SVGHYTHVKCKPKYQLYDACNVNKVSEAKGNFTDCL 1905
Query 1868 YKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--NAS 1924
Y +N T + T+ LD V C E P L YY + Y+T +PI + + +
Sbjct 1906 YLKNLKQTFSSVLTTFYLDDVKCVEYKPDLSQYYCESGKYYT-KPIIKAQFRTFEKVDGV 1964
Query 1925 FDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK V +I A+ LN G+ E K+T +P GDVV Y + G
Sbjct 1965 YTNFKLVGHSI--AEKLNAKLGFDCNSPFVEYKITEWPTATGDVVLASDDLYVSRYSSGC 2022
Query 1984 KLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVETSNSFDV-----------L 2028
KP+VW H + TY +P+ C ++ PV+ S D +
Sbjct 2023 ITFGKPVVWLGHEEASLKSLTYFNRPSVVC-ENKFNVLPVDVSEPTDKGPVPAAVLVTGV 2081
Query 2029 KSEDAQGMDNLACEDLKPVSE--------EVVENPTIQ-KDVLECNV----KTTEVVGDI 2075
DA +A E S EV + P++ DV E + K +V G +
Sbjct 2082 PGADASAGAGIAKEQKACASASVEDQVVTEVRQEPSVSAADVKEVKLNGVKKPVKVEGSV 2141
Query 2076 ILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPW 2135
++ + K+ + + D+ ++ + NELSR+ VNS
Sbjct 2142 VVNDPTSETKVVKSLSIVDVYDMFLTGCKYVVWTANELSRL-------------VNS--- 2185
Query 2136 DTIANYAKPFLNKVVSTTTNIVTRCLNR-------------VCTNYMPYFFTLLLQLCTF 2182
T+ Y K + K+V+ ++ R + C + +F F
Sbjct 2186 PTVREYVKWGMGKIVTPAKLLLLRDEKQEFVAPKVVKAKAIACYCAVKWFLLYCFSWIKF 2245
Query 2183 TRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLIN--------IIIW-- 2232
N+ K T +A K K C A N L++ N+S + ++W
Sbjct 2246 ----NTDNKVIYTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVFLLWFN 2298
Query 2233 FLLLSVCLGSL---------IYSTAALGVLMSNLGMPSYCTGYRE---GYLNSTNVTIAT 2280
FL +V L + + + G+ + C Y+ GY +S
Sbjct 2299 FLYANVILSDFYLPNIGPLPTFVGQIVAWFKTTFGVSTICDFYQVTDLGYRSS------- 2351
Query 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLTAFGLVAEWFLAYILFTRF 2337
+C GS+ C +C SG D LD Y ++ +Q + SF + ++ F LV E + Y L+T
Sbjct 2352 FCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRLSFDY-ISLFKLVVELVIGYSLYTVC 2410
Query 2338 FYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWK 2395
FY L + MQL ++ F+ + W L + + M P ++R YI + Y V+
Sbjct 2411 FYPLFVLIGMQLLTTWLPEFFMLETMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVYC 2470
Query 2396 SYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNC 2455
HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC+NC
Sbjct 2471 LCRHVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLNC 2530
Query 2456 DTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYER 2515
+++ G+TFI+ E A DLS + KRP+NPTD + Y V V S+ L++++ GQ+ Y+
Sbjct 2531 NSWKPGNTFITHEAAADLSKELKRPVNPTDSAYYSVTEVKQVGCSMRLFYERDGQRVYDD 2590
Query 2516 HSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQA 2575
+ S FV+++ L + KG +V+V + ++ +++ A+V+Y+Q + +P+L++++
Sbjct 2591 VNASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLGAAVFYAQSLYRPMLMVEKK 2648
Query 2576 LVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFIS 2635
L++ V+ MFD YV++ + +V + L + V A L + V L+ V+ TFI
Sbjct 2649 LITTANTGLSVSRTMFDLYVDSLLNVLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFIG 2708
Query 2636 AARQG-FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDC 2694
AR+ +DSDVETK + + + + + ++ T +SCNN + TY K + + DLG I
Sbjct 2709 CARRKCAIDSDVETKSITKSVMSAVNAGVDFTDESCNNLVPTYVKSDTIVAADLGVLIQN 2768
Query 2695 SARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVV 2754
+A+H+ A VAK+ N+A IW+V F LS L+ ++R A K L KLT V ++
Sbjct 2769 NAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQEANVPIL 2828
Query 2755 TTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDG 2814
TT +LKGG + + L+ L L+ V + + P + + K +K ID
Sbjct 2829 TTPFSLKGGAVFSRMLQWLFVANLICFIV---LWALMPTYAVHKSDMQLPLYASFKVIDN 2885
Query 2815 GVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGT 2872
GV RD++ TD CFANK FD W+ G Y N KACP++ AVI +++G + +P T
Sbjct 2886 GVLRDVSVTDACFANKFNQFDQWYESTFGLAYYRNSKACPVVVAVIDQDIGHTLFNVPTT 2945
Query 2873 ILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPY 2932
+LR LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P PY
Sbjct 2946 VLR-YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHPY 3004
Query 2933 CYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCER 2991
CY V+ + Y SL P RY L + I+FP EG VRVV T YCR G CE
Sbjct 3005 CYTGGVMHNASLYSSLAPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLCEE 3064
Query 2992 SEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGG 3051
+E G+C + + WVLNN YYR++PG FCG +A +L+ + L++PI ++AS VAG
Sbjct 3065 AEEGICFNFNRSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALTASSVAGA 3124
Query 3052 IVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLY 3111
I+AI+V YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L +Y+ Y Y
Sbjct 3125 ILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFY 3184
Query 3112 LTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVS 3171
T Y +++S + H+QW+VM+ ++P W I Y+ + + H W FS R++ S
Sbjct 3185 TTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFS--YCRKIGTEVRS 3242
Query 3172 FSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAAC 3231
TFEE AL TF++ KE Y KL++ V +NRYL+LYNKY+YFSG MDT +YREAAC
Sbjct 3243 DGTFEEMALTTFMITKESYCKLKNSV--SDVAFNRYLSLYNKYRYFSGKMDTAAYREAAC 3300
Query 3232 CHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTL 3290
LAKA+ F+ N+G+DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G TL
Sbjct 3301 SQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCIVSVTYGNMTL 3360
Query 3291 NGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVL 3350
NGLWLDD VYCPRHVIC+S DM +P+Y +LL R ++ +F V +G + L V+ + MQ C L
Sbjct 3361 NGLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSGRMSLTVMSYQMQGCQL 3420
Query 3351 KLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGS 3410
L V NP TPKY F ++PG+TF+VLA YNG P G + +R + TIKGSFL GSCGS
Sbjct 3421 VLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVTLRSSHTIKGSFLCGSCGS 3480
Query 3411 VGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAW 3470
VG+ + D V F YMH +EL TG H GTD GNFYGP+ D Q Q D T TVNV+AW
Sbjct 3481 VGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAW 3540
Query 3471 LYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAS 3530
LYAA+ N WF+ + +L +FN+ AM + + D V L L++ TG+ V + A+
Sbjct 3541 LYAAIFNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVLAA 3598
Query 3531 LKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTS 3590
+K L +G G+ ILGS +LEDE TP DV +Q +GV QS R IKGT W+L +
Sbjct 3599 IKR-LHSGFQGKQILGSCVLEDE-TPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTFLF 3656
Query 3591 LLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYF 3650
++ +W++F ++ + L + + +FAM+ +KHKH +L ++++P L T
Sbjct 3657 CSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLIKHKHLYLTMYIMPVLCTFYTN 3715
Query 3651 NMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILM---TARTVYDDGARR 3707
+V S+ WL ++ + D V+Y VVLL+ M T R++ D
Sbjct 3716 YLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLY--GVVLLVAMVFVTMRSINHDVFSI 3772
Query 3708 VWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARG-IVFMCVEYC 3766
++ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA ++ +
Sbjct 3773 MFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKWLAVN 3828
Query 3767 PIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQ 3826
++F ++ ++L Y +GY C CY+G+ LLN FR+ LGVY+Y +S QE RYMN+
Sbjct 3829 VLYFTDVPQIKLVLLSYLCIGYVCCCYWGILSLLNSIFRMPLGVYNYKISVQELRYMNAN 3888
Query 3827 GLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSK 3886
GL PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+SK
Sbjct 3889 GLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNSK 3948
Query 3887 LWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRAT 3940
LW C LHN+IL D + AF+K+ LL VL + AVD I ++ ++ + +
Sbjct 3949 LWQYCSTLHNEILATSDLSMAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNTV 4008
Query 3941 LQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQR 3999
LQA+ SEF ++ S+ + A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ R
Sbjct 4009 LQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVAR 4068
Query 4000 KLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPL 4059
KLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPL
Sbjct 4069 KLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPL 4128
Query 4060 NIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNS 4119
N IP T+ L +++PD + D TYA +W IQ + DAD + QL+EI ++++
Sbjct 4129 NAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDVNST 4188
Query 4120 PNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKG 4177
WPL++ A R N S V LQNNEL P LR +G+ T YYNTT
Sbjct 4189 ----WPLVIAANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQ--CYYNTTGT 4242
Query 4178 GRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNL 4237
G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L
Sbjct 4243 GKIVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNTL 4301
Query 4238 NRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKM 4297
RG V+G+L++TVRLQAG ATE +NS +LS CAF+VD K Y DY+ GG P+TNCVKM
Sbjct 4302 ARGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIKQGGVPVTNCVKM 4361
Query 4298 LCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCA 4357
LC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P
Sbjct 4362 LCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-I 4420
Query 4358 NDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGT 4416
DPV + L + VC VCG W+ CSC QS D +FLNR+ G S ARL PC +
Sbjct 4421 KDPVSYVLTHDVCQVCGFWRDGSCSCVGTGS-QFQSKDT-NFLNRIRGTSVNARLVPCAS 4478
Query 4417 GTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEE 4476
G TDV RAFDI N AG + K NCCRFQ DED N +D +FVVKR Y E+
Sbjct 4479 GLDTDVQLRAFDICNANRAGIGLYYKVNCCRFQRVDEDGNKLDKFFVVKRTNLEVYNKEK 4538
Query 4477 TIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKE 4536
Y L K+C VA+H+FF F ++G VPHI R+ L+K+TM DL YALRHFD +C TLKE
Sbjct 4539 ECYELTKECGVVAEHEFFTFDVEGSRVPHIVRKDLSKFTMLDLCYALRHFDRNDCSTLKE 4598
Query 4537 ILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGV 4596
IL+TY C++ YF KKDWYDFVENPDI+ VY LG +ALL T +F DA+ AG+VGV
Sbjct 4599 ILLTYAECEESYFQKKDWYDFVENPDIINVYKKLGPIFNRALLNTAKFADALVEAGLVGV 4658
Query 4597 LTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKP 4656
LTLDNQDL G WYDFGDF++T PG GV V DSYYS +MP+LT+ AL +E V+
Sbjct 4659 LTLDNQDLYGQWYDFGDFVKTVPGCGVAVADSYYSYMMPMLTMCHALDSELFVN----GT 4714
Query 4657 YIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPT 4716
Y ++DL++YDFT+ +L+LF +YFK+W TYHPN C DDRCI+HCANFN+LFS V P T
Sbjct 4715 YREFDLVQYDFTDFKLELFTKYFKHWSMTYHPNTCECEDDRCIIHCANFNILFSMVLPKT 4774
Query 4717 SFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAAS 4776
FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+LL+YAADPA+H AS
Sbjct 4775 CFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYRLSLKDLLLYAADPALHVAS 4834
Query 4777 GNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQ 4836
+ LLD RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +SKG KEGSSV+LKHFFF Q
Sbjct 4835 ASALLDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSVDLKHFFFTQ 4894
Query 4837 DGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGF 4896
DGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV+KYF+ Y+GGCI A QVIVNN DKSAG+
Sbjct 4895 DGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVNKYFEIYEGGCIPATQVIVNNYDKSAGY 4954
Query 4897 PFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICS 4956
PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI S
Sbjct 4955 PFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILS 5014
Query 4957 TMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDR 5016
TMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPKCDR
Sbjct 5015 TMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPKCDR 5074
Query 5017 AMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGD 5076
AMPN+LRI++SLVLARKH +CCS + RFYRLANECAQVLSE+VMCGG YVKPGGTSSGD
Sbjct 5075 AMPNILRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLSEIVMCGGCYYVKPGGTSSGD 5134
Query 5077 ATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNE 5136
ATTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD FV+E
Sbjct 5135 ATTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVSE 5194
Query 5137 FYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETD 5196
+Y +L KHFSMMILSDD VVC+NS +AS+G +A+I F+ VLYYQNNVFMSEAKCW ETD
Sbjct 5195 YYEFLNKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQVLYYQNNVFMSEAKCWVETD 5254
Query 5197 LTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAI 5256
+ KGPHEFCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFVSLAI
Sbjct 5255 IEKGPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFVSLAI 5314
Query 5257 DAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAM 5316
DAYPL H N EY +VF +YL+YI+KL+++L +LD YSV+L+ + ++ + FY+ M
Sbjct 5315 DAYPLVYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSYSVILSTCDGQKFTDETFYKNM 5374
Query 5317 YTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNA 5376
Y VLQ+VGACV+C+SQTSLRCG+CIR+P LCCKC YDHV+ST HK VLSV+PYVCN+
Sbjct 5375 YLRSAVLQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVLSVSPYVCNS 5434
Query 5377 PGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATC 5436
PGCDV DVT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS + DFN IA+C
Sbjct 5435 PGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYIEDFNKIASC 5494
Query 5437 DWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKP 5496
WT DY+LAN CTERLKLFAAET KATEE FK Y AT+RE++SDREL LSWE+GK
Sbjct 5495 KWTEVDDYVLANECTERLKLFAAETQKATEEAFKQCYASATIREIVSDRELILSWEIGKV 5554
Query 5497 RPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTV 5556
RPPLN+NYVFTGY T N K +GEY F+K + + V YR TTTYKL+VGD F+LTSH V
Sbjct 5555 RPPLNKNYVFTGYHFTNNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFILTSHAV 5614
Query 5557 MPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSH 5614
LSAPTLVPQE+Y +R +Y ++ + F +NV NYQ +GM++Y T+QGPPGTGKSH
Sbjct 5615 SSLSAPTLVPQENYTSIRFASVY---SVPETFQNNVPNYQHIGMKRYCTVQGPPGTGKSH 5671
Query 5615 FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNS 5674
AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RV+C+DKFKVN
Sbjct 5672 LAIGLAVYYCTARVVYTAASHAAVDALCEKAHKFLNINDCTRIVPAKVRVDCYDKFKVND 5731
Query 5675 TLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRT 5734
T +YVF T+NALPE DI+V DE+SM TNY+LSV+N+R+RAKHYVYIGDPAQLPAPR
Sbjct 5732 TTRKYVFTTINALPELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGDPAQLPAPRV 5791
Query 5735 LLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ 5794
LL KGTLEP YFNSV +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA D S+
Sbjct 5792 LLNKGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYNNKLKAKNDNSSM 5851
Query 5795 CFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPT 5854
CFK++YKG TH+ SSA+N QI ++ +FL NP+W AVFISPYNSQN VA ++LGL T
Sbjct 5852 CFKVYYKGQTTHESSSAVNMQQIHLISKFLKANPSWSNAVFISPYNSQNYVAKRVLGLQT 5911
Query 5855 QTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSL 5914
QTVDS+QGSEYD+VI++QT ETAHS NVNRFNVAITRAK GILC+MS L++ L FT+L
Sbjct 5912 QTVDSAQGSEYDFVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSSMQLFESLNFTTL 5971
Query 5915 EIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKD 5973
+ + N LQ T LFKDCS+ G HP AP+ L+VD K+K G L V +
Sbjct 5972 TLDKINNPRLQC--TTNLFKDCSRSYVGYHPAHAPSFLAVDDKYKVGGDLAVCLNVADSA 6029
Query 5974 MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQ 6033
+TY RLIS+MGFK++ ++GY +FITR+EAI+ VRAW+GFD EG HA R+++GTN PLQ
Sbjct 6030 VTYSRLISLMGFKLDLTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHAIRDSIGTNFPLQ 6089
Query 6034 LGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQ 6093
LGFSTG++ V TG + F + +A+ PPG+QFKHLIPLM +G W+VVRI+IVQ
Sbjct 6090 LGFSTGIDFVVEATGMFAERDGYVFKKAAARAPPGEQFKHLIPLMSRGQKWDVVRIRIVQ 6149
Query 6094 MLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWH 6153
MLSD L +L+D VV V WA FELT ++YF K+G E C +C +RATCF++ + Y CW
Sbjct 6150 MLSDHLVDLADSVVLVTWAASFELTCLRYFAKVGREVVCSVCTKRATCFNSRTGYYGCWR 6209
Query 6154 HSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVK 6213
HS DY+YNP ++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+CF K
Sbjct 6210 HSYSCDYLYNPLIVDIQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRCLAVHDCFCK 6269
Query 6214 RVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEW 6273
V+W +EYPII +E+ +N +CR +Q ++ +AA+L +++ V +DIGNPK + CV D +
Sbjct 6270 SVNWNLEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKGYD--F 6327
Query 6274 KFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSN 6333
KFYDA P +++ Y Y H D+F DG+C+FWNCNVD+YPAN++VCRFDTRVL+
Sbjct 6328 KFYDASPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLNK 6384
Query 6334 LNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPL 6393
LNLPGC+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD+PC +DYVPL
Sbjct 6385 LNLPGCNGGSLYVNKHAFHTSPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPL 6444
Query 6394 KSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQS 6453
+SATCITRCNLGGAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFTRLQS
Sbjct 6445 RSATCITRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQS 6504
Query 6454 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 6513
LENV +N+VN GHFDG+ GE+P ++I V K+ DV +F+N T P NVA EL+AKR
Sbjct 6505 LENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAKR 6564
Query 6514 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 6573
+I+P PE+K+ NL +D+ + V+WDY +D+ ST VC TD+ L V
Sbjct 6565 SIRPHPELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVCKYTDL------QCIESLNV 6618
Query 6574 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEA-VKTQFNY 6630
FDGR +G ++ F+ RNGV I +K L GP++A LNGV + +G++ V+ F
Sbjct 6619 LFDGRDNGALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFAV 6678
Query 6631 YKKVDGVV-----------QQLPE--------------------TYFTQSRNLQEFKPRS 6659
K D V+ + P+ T FTQSR L F PRS
Sbjct 6679 RKDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRLLSSFTPRS 6738
Query 6660 QMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELED 6719
+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHLLIGLA+R ++S +++
Sbjct 6739 EMEKDFMDLDDDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRQQKSNLVIQE 6798
Query 6720 FIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEI 6779
F+ DS++ +YFITD +GSSK VC+VIDLLLDDFV+I+KS +L VSKVV V +D+ +
Sbjct 6799 FVTYDSSIHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKSLNLKCVSKVVNVNVDFKDF 6858
Query 6780 SFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIM 6839
FMLWC + V TFYP+LQ++ W+PG MP LYK LE+ +L NYG TLP G M
Sbjct 6859 QFMLWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPLERVNLWNYGKPITLPTGCM 6918
Query 6840 MNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLN 6899
MNVAKYTQLCQYL+T TLAVP NMRV+H GAGSDKGVAPG+AVLRQWLP G++LVD+D+N
Sbjct 6919 MNVAKYTQLCQYLSTTTLAVPANMRVLHLGAGSDKGVAPGSAVLRQWLPAGSILVDNDVN 6978
Query 6900 DFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKL 6959
FVSD+ ++ G+C T+ +WDLIISDMYDP TKN+ + N SK+GFFTY+C I+ KL
Sbjct 6979 PFVSDSVASYYGNCITLPFDCQWDLIISDMYDPLTKNIGEYNVSKDGFFTYLCHLIRDKL 7038
Query 6960 ALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDG 7019
ALGGSVAIKITE SWNA+LY LMG FA+WT F TNVNASSSE FLIG N+L K R +IDG
Sbjct 7039 ALGGSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWLNKTRTEIDG 7098
Query 7020 YVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLI 7079
MHANY+FWRN+ +YSLFDMSKFPLK GTAV+SLK QIND++LSL+ KG+L+
Sbjct 7099 KTMHANYLFWRNSTMWNGGAYSLFDMSKFPLKAAGTAVVSLKPDQINDLVLSLIEKGKLL 7158
Query 7080 IRENNRVVISSDVLVN 7095
+R+ + V D LVN
Sbjct 7159 VRDTRKEVFVGDSLVN 7174
Score = 79.0 bits (193), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 67/252 (27%), Positives = 118/252 (47%), Gaps = 20/252 (8%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV D+++ + V V+VN AN + HG GVAGA+ + +A E+ D +
Sbjct 1320 ITPNVCFVKGDVIKVVRLVNAEVIVNPANGRMAHGAGVAGAIAEKAGSAFIKETSDMVKA 1379
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENFNQHEVLLAPLLS 1150
G +VG +G L K L++VGP+ +G Q LL+ AY++ N+ + ++ L+S
Sbjct 1380 QGVCQVGECYESAGGKLCKKVLNIVGPDA-RGHGKQCYSLLERAYQHINKCDNVVTTLIS 1438
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + V NV L +++ +D + + K + ++A+
Sbjct 1439 AGIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFDVIEKCQVTSVAGTKALSLQLAKNLCR 1498
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+VK F+T + S+ ++C L+E + L ++ L ++ N +
Sbjct 1499 DVK-FVTNACSSLFS--------ESCFVSSYDVLQEVEALRHDIQLDDDARVFVQANMDC 1549
Query 1264 HPDSATLVSDID 1275
P LV+ D
Sbjct 1550 LPTDWRLVNKFD 1561
Score = 74.3 bits (181), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 108/457 (24%), Positives = 188/457 (41%), Gaps = 59/457 (13%)
Query 569 ILDGISQYSLRLIDA-MMFTSDLA------TNNLVVMAYITGGVVQLTSQWLTNIFGTVY 621
+LDG+ S LI + FTS + T+ + MA + V++ ++++ + G +
Sbjct 576 LLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMALLFMHDVKVATKYVKKVTGKLA 635
Query 622 EKLKPVLDWLEEKFKEGVEFLRD------GWEIVKFISTCACEIVGGQIVTCAKEIKESV 675
+ K + + K E + D GW + ++ V ++T +E+ E V
Sbjct 636 VRFKALGVAVVRKITEWFDLAVDIAASAAGWLCYQLVN--GLFAVANGVITFVQEVPELV 693
Query 676 QTFFKLVNKFLALCADSI---IIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMP 732
+ F F + DS+ I+ G + + SK +Y V + + +MP
Sbjct 694 KNFVDKFKAFFKVLIDSMSVSILSGLTVVKTASNRVCLAGSK-VYE--VVQKSLSAYVMP 750
Query 733 LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTPVCINGLML 790
+ E L GE P V + + ++ P + + P +CI +
Sbjct 751 VGC-SEATCLVGEIEPA-------VFEDDVVDVVKAPLTYQGCCKPPTSFEKICIVDKLY 802
Query 791 LEIKDTEKYCALAPN--MMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGYKSVNITFELDE 847
+ + Y + N + V + + A KV F D V ++ + + ITF LD
Sbjct 803 MAKCGDQFYPVVVDNDTVGVLDQCWRFPC-AGKKVEFNDKPKVRKIPSTRKIKITFALDA 861
Query 848 RIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPLGIDLDEWSMAT 904
D VL++ CS + V+ ++E VV DAV TL P E + T + LD +
Sbjct 862 TFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEHDVIGTKVCALLDRLAGDY 921
Query 905 YYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGA 964
YLFDE G+ +A MYCSF PD++ DC + + + + +DD A
Sbjct 922 VYLFDEGGDEVIAPRMYCSFSAPDDE----DCVAADVVDADENQ---DDD---------A 965
Query 965 TSAALQPEEEQEED-----WLDDDSQQTVGQQDGSED 996
+A+ + QEED ++ DS+ V E+
Sbjct 966 EDSAVLVADTQEEDGVAKGQVEADSEICVAHTGSQEE 1002
>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152
Score = 5341 bits (13856), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2744/5618 (49%), Positives = 3655/5618 (65%), Gaps = 175/5618 (3%)
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1620 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1679
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1680 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1738
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1739 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1798
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF+
Sbjct 1799 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPFL 1856
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ + G GHY H+ D + K + G +TD
Sbjct 1857 ICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLTD 1914
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--N 1922
Y +N + T T Y LD V +P L YY + Y+T +PI +P+ +
Sbjct 1915 CLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKVD 1973
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I LN G+ E KVT +P GDVV Y + K
Sbjct 1974 GVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2031
Query 1982 GAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNL 2039
G + KP++W H + N TY ++ ++ N + VL +D++
Sbjct 2032 GCETFGKPVIWLCHDEASLNSLTY----------FNKPSFKSENRYSVL------SVDSV 2075
Query 2040 ACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAA 2098
+ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2076 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2135
Query 2099 YVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTN 2155
Y+ + NELSR++ T+ +G+ + ++P D + N+ +
Sbjct 2136 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRDD---NQTLLVPKI 2191
Query 2156 IVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASF 2215
R + ++ + F + L FT T IA ++ L+ +F
Sbjct 2192 FKARAIEFY--GFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAF 2245
Query 2216 NYLKSPNFSKLINII-----IWF--LLLSVCLGSL---------IYSTAALGVLMSNLGM 2259
+ F K ++ WF L ++V I+ + + + G+
Sbjct 2246 QTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGL 2305
Query 2260 PSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISS---FKW 2316
+ C Y + + T + +C GS C +C SG D LDTY +++ +Q + F +
Sbjct 2306 VTICDFYSKLGVGFT----SHFCNGSFICELCYSGFDMLDTYAAIDFVQYEVDRRVLFDY 2361
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2362 -VSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2420
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2421 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2480
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2481 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2540
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + S + ++
Sbjct 2541 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVE--SDADRANF 2598
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2599 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVN 2658
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2659 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2718
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK+ NI+ IW + F L+ L+ +++ A
Sbjct 2719 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDTFNQLTADLQHKLKKAC 2778
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L ++L+ + + + P
Sbjct 2779 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPT 2835
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGS--YTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ GS Y N C
Sbjct 2836 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSFYYHNSMDC 2895
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2896 PIVVAVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2954
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2955 GCVLSSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 3014
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 3015 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQF 3074
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3075 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFL 3134
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3135 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3194
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N + STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3195 NHVLWLFS--YCRKIGVNVCNDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3250
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3251 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3310
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R + +F
Sbjct 3311 VSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDF 3370
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3371 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAF 3430
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3431 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYR 3490
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM + + D
Sbjct 3491 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADL 3550
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3551 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3607
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3608 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3666
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3667 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGLTYVWLSYFVPAVNFTYVYEVFYGCIL 3726
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3727 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3782
Query 3749 TTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3783 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3842
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3843 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKC 3902
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD- 3926
+VVLL+ LQ L V S+S+LW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3903 ANVVLLNCLQHLHVASNSRLWQYCSILHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDT 3962
Query 3927 -----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKL 3980
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L
Sbjct 3963 KCLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQL 4022
Query 3981 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4040
+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKL
Sbjct 4023 EKACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKL 4082
Query 4041 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQ 4100
DN ALN+I++NA GCVPLN IP A L ++IPD + D YA ++W IQ
Sbjct 4083 DNQALNSILDNAVKGCVPLNAIPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQT 4142
Query 4101 VVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGT 4158
V DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4143 VQDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGS 4198
Query 4159 TQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTD 4218
+ YYN GR V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4199 DMNC--NIPTQCYYNNGSSGRIVYAVLSDVDGLKYTKIIKDDGNCVV-LELDPPCKFSIQ 4255
Query 4219 TPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK 4278
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VD K
Sbjct 4256 DVKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKK 4315
Query 4279 AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPN 4338
Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+
Sbjct 4316 TYLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPD 4375
Query 4339 PKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQS 4398
G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D +
Sbjct 4376 VDGLCKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SGVAVQSKDL-N 4432
Query 4399 FLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNL 4457
FLNRV G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D+D N
Sbjct 4433 FLNRVRGTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRIDDDGNK 4492
Query 4458 IDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMA 4517
+D +FVVKR Y E+T Y L K C VA+HDFF F IDG VPHI R+ L+KYTM
Sbjct 4493 LDKFFVVKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRKNLSKYTML 4552
Query 4518 DLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQA 4577
DL YALRHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG +A
Sbjct 4553 DLCYALRHFDCNDCSVLCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGPIFNRA 4612
Query 4578 LLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPIL 4637
LL TV F D + G+VGVLTLDNQDL G WYDFGDFIQT PG GV V DSYYS +MP+L
Sbjct 4613 LLNTVSFADTLVKVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSYMMPML 4672
Query 4638 TLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDR 4697
T+ L E V+ Y ++DL++YDFT+ +L+LF++YFKYW YHPN V+C +DR
Sbjct 4673 TMCHVLDCELFVN----DSYRQFDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVDCDNDR 4728
Query 4698 CILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSR 4757
CI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H R
Sbjct 4729 CIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVDTHRYR 4788
Query 4758 LSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVS 4817
LS K+LL+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY+F S
Sbjct 4789 LSLKDLLLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFYEFVKS 4848
Query 4818 KGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDG 4877
KG FKEGS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDG
Sbjct 4849 KGLFKEGSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDG 4908
Query 4878 GCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLK 4937
GCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+TQMNLK
Sbjct 4909 GCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLTQMNLK 4968
Query 4938 YAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTV 4997
YAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ +
Sbjct 4969 YAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRHL 5028
Query 4998 YSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSE 5057
DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS RFYRLANECAQVLSE
Sbjct 5029 IKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECAQVLSE 5088
Query 5058 MVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQH 5117
+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +RNLQ
Sbjct 5089 IVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSIRNLQK 5148
Query 5118 RLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSV 5177
RLY +YR VD FVNE+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I F+ V
Sbjct 5149 RLYSNVYRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYASKGYIANISVFQQV 5208
Query 5178 LYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVD 5237
LYYQNNVFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGAGCFVD
Sbjct 5209 LYYQNNVFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGAGCFVD 5268
Query 5238 DIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSV 5297
D++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD YSV
Sbjct 5269 DLLKTDSVLLIERFVSLAIDAYPLVHHENEEYQKVFRVYLEYIKKLYNDLGNQILDSYSV 5328
Query 5298 MLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDH 5357
+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDH
Sbjct 5329 ILSTCDGLKFTDESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDH 5388
Query 5358 VISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLY 5417
V++T+HK VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG VFGLY
Sbjct 5389 VMATNHKYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGMVFGLY 5448
Query 5418 KNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIAT 5477
K +C GS + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK SY AT
Sbjct 5449 KQSCTGSPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQSYASAT 5508
Query 5478 VREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRG 5537
++E++SDRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + + V YR
Sbjct 5509 IQEIVSDREIILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNGVYYRA 5568
Query 5538 TTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLY--PTLNISDEFSSNVANY 5593
TTTYKL++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y P L F +NVANY
Sbjct 5569 TTTYKLSIGDVFVLTSHSVANLSAPTLVPQENYASIRFSSVYSVPLL-----FQTNVANY 5623
Query 5594 QKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDK 5653
Q +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+
Sbjct 5624 QHIGMKRYCTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLNIND 5683
Query 5654 CSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNA 5713
C+RIIPA+ RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NA
Sbjct 5684 CTRIIPAKVRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSVINA 5743
Query 5714 RLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIV 5773
R++AKHYVYIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP EIV
Sbjct 5744 RVKAKHYVYIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPKEIV 5803
Query 5774 DTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKA 5833
+TVSALVYDNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W A
Sbjct 5804 ETVSALVYDNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVWNSA 5863
Query 5834 VFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAK 5893
VFISPYNSQN VA +ILG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK
Sbjct 5864 VFISPYNSQNYVAKRILGVQTQTVDSAQGSEYDYVIYSQTAETAHSINVNRFNVAITRAK 5923
Query 5894 VGILCIMSDRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKVITGLHPTQAPTHL 5952
GI C+MS+ L++ L F +L + + TL + T LFKDCSK G HP AP+ L
Sbjct 5924 KGIFCVMSNMQLFESLNFITLPLDKIQNQTLSRLHCTTNLFKDCSKNFLGYHPAHAPSFL 5983
Query 5953 SVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAW 6011
SVD K+K E L V + +TY RLIS+MGFK++ ++GY FIT++EAI+ VR W
Sbjct 5984 SVDDKYKVNEDLAVCLNICEPVLTYSRLISLMGFKLDLTLDGYSKFFITKDEAIKRVRGW 6043
Query 6012 IGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQF 6071
+GFDVEG HATR+ +GTN PLQ+GFSTGV+ V TG + F R AK PPGD F
Sbjct 6044 VGFDVEGAHATRDNIGTNFPLQIGFSTGVDFVVEATGLFAERDCYIFKRTVAKAPPGDNF 6103
Query 6072 KHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERT 6131
KHLIPLM KG W+VVRI+IVQMLSD L +LSD VVF+ W+ FELT ++YF K+G E
Sbjct 6104 KHLIPLMSKGQKWDVVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGRELN 6163
Query 6132 CCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGN 6191
C +C RATC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD+ C VH
Sbjct 6164 CDVCPNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNVHKG 6223
Query 6192 AHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKF 6251
AHVAS DAIMTRCLA+++CF K V+W +EYPII +E+ IN +CR +Q +++KAA+L +++
Sbjct 6224 AHVASSDAIMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLCNRY 6283
Query 6252 PVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWN 6311
+ +DIGNPK I CV D E+KFYDA P +++LFY Y H D F DG+C+FWN
Sbjct 6284 NLCYDIGNPKGIACVK--DYEFKFYDASPV---VKSVKQLFYVYDVHKDNFKDGLCMFWN 6338
Query 6312 CNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFY 6371
CNVD+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +PFFY
Sbjct 6339 CNVDKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMPFFY 6398
Query 6372 YSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGF 6431
YSD+PC +DYVPL+SATCITRCNLGGAVC HA +Y YL++YN+ +AGF
Sbjct 6399 YSDTPCVYVDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEDYCKYLESYNVATTAGF 6458
Query 6432 SLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVD 6491
+ WVYK FD YNLWNTFT LQSLENV +N+VN GH+DG+ GE+P +I+N+ V K++ VD
Sbjct 6459 TFWVYKTFDFYNLWNTFTMLQSLENVIYNLVNAGHYDGRIGELPCAIMNDKVVVKINNVD 6518
Query 6492 VELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTI 6551
+F+N T+LP N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +D+ ST
Sbjct 6519 TVIFKNNTSLPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTY 6578
Query 6552 GVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQ 6611
GVC TD+ L V FDGR +G ++ FR ARNGV I+ G + L GP++
Sbjct 6579 GVCKYTDL------NFIENLNVLFDGRDNGALEAFRKARNGVFISTGKLSSLSMIKGPQR 6632
Query 6612 ASLNGVTL--IGEA-VKTQFNYYKKVDGVVQQLPE------------------------- 6643
A LNGV + +GE V+ F K D V+ +
Sbjct 6633 ADLNGVIVDKVGELNVEFWFAMRKDGDDVIFSRADSLSPSHYWSPQGNLGGNCAGNASGN 6692
Query 6644 ------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQL 6697
T FTQSR L F+PRS +E DF+++ FI +Y LE YAF+HIVYG F++ +
Sbjct 6693 DALARFTIFTQSRVLSTFEPRSDLERDFIDMEDSLFIAKYGLEDYAFDHIVYGSFNYKVI 6752
Query 6698 GGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEI 6757
GGLHLLIGL +R K+S +++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I
Sbjct 6753 GGLHLLIGLFRRLKKSNLVIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVVI 6812
Query 6758 IKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQR 6817
+KS +L+ VSKVV + +D+ + FMLWC D + TFYPK+Q++ W+PG +MP LYK
Sbjct 6813 VKSLNLNCVSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATSDWKPGYSMPVLYKYLN 6872
Query 6818 MLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVA 6877
+ LE+ L NYG + LP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VA
Sbjct 6873 VPLERVSLWNYGKAINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSDKEVA 6932
Query 6878 PGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNV 6937
PG+AVLRQWLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP TKN+
Sbjct 6933 PGSAVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPLTKNI 6992
Query 6938 TKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNA 6997
N SK+GFFTYIC I+ KL+LGGSVAIKITE SWNADLYKLM +FA+WT F TNVNA
Sbjct 6993 GDYNVSKDGFFTYICYLIRDKLSLGGSVAIKITEFSWNADLYKLMSYFAFWTVFCTNVNA 7052
Query 6998 SSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAV 7057
SSSE FLIG NYLGK +IDG VMHANY+FWRN+ +YSLFDMSKF LKL GTAV
Sbjct 7053 SSSEGFLIGINYLGKSCFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMSKFSLKLAGTAV 7112
Query 7058 MSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
++L+ Q+ND++ SL+ +G+L++R+ + + D LVN
Sbjct 7113 VNLRPDQLNDLVYSLIERGKLLVRDTRKEIFVGDSLVN 7150
Score = 81.6 bits (200), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 53/155 (34%), Positives = 79/155 (51%), Gaps = 2/155 (1%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A E+ +
Sbjct 1328 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1387
Query 1092 ATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHEVLLAPLL 1149
+ G +VG V +G L K L++VGP+ + + LL AY++ N ++ L+ L+
Sbjct 1388 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1447
Query 1150 SAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
SAGIF SL + V V L +K +D
Sbjct 1448 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFD 1482
Score = 73.6 bits (179), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 102/422 (24%), Positives = 172/422 (41%), Gaps = 63/422 (15%)
Query 562 LQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW-------- 612
L ++ I +SQ+S + D + L + + V YI V +L +Q+
Sbjct 562 LIQSGIFFTSLMSQFSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLV 621
Query 613 --LTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKE 670
+ N F T+ + P WL + G+ F+ + A I AK
Sbjct 622 NKMVNWFNTMLDASAPATGWLLYQLLNGL-----------FVVSQANFNFVALIPDYAKI 670
Query 671 IKESVQTFFKLVNKFLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSRE 725
+ TFFKL+ L ++ LK +N +G F S GL
Sbjct 671 LVNKFYTFFKLL---LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI-------- 719
Query 726 ETGLLMPLKA-PKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTP 782
G ++P A ++I F EG + E V+++ ++ ++ S E + P
Sbjct 720 -PGFVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEK 771
Query 783 VCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGG-----APTKVTFGDDTVI-EVQGY 836
+CI M + K +K+ P +M N L A KV F + V+ E+
Sbjct 772 ICIIDNMYMG-KCGDKF---FPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 837 KSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPL 893
+V + F+LD D +L + CS + VE G V++F VV DA+ L + + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKDHPVVGYQV 887
Query 894 GIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTE 952
L++ + YLFDE+G+ +AS MYC+F D ED + E+ + + +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 953 DD 954
+D
Sbjct 948 ED 949
Score = 44.3 bits (103), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 16/148 (11%)
Query 1658 YPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAY 1717
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1115 YFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTT 1174
Query 1718 CNKTV--GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
K + + G V + + ++++ N C CG L G++AV + G +
Sbjct 1175 IPKAIVLPQGGYVADFAYWFLNQFDINA---YANWCCLKCG-FSFDLNGLDAVFFYGDI- 1229
Query 1776 YEQFKKGVQIPCTCGKQATKYLVQQESP 1803
V C CG T L+ + P
Sbjct 1230 -------VSHVCKCGHNMT--LIAADLP 1248
>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132
Score = 5340 bits (13853), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2744/5622 (49%), Positives = 3662/5622 (65%), Gaps = 183/5622 (3%)
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1600 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1659
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1660 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1718
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1719 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1778
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF+
Sbjct 1779 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPFL 1836
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ + G GHY H+ D + K + G +TD
Sbjct 1837 ICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLTD 1894
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--N 1922
Y +N + T T Y LD V +P L YY + Y+T +PI +P+ +
Sbjct 1895 CLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKVD 1953
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I LN G+ E KVT +P GDVV Y + K
Sbjct 1954 GVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2011
Query 1982 GAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNL 2039
G + KP++W H + N TY ++ ++ N + VL +D++
Sbjct 2012 GCETFGKPVIWFCHDEASLNSLTY----------FNKPSFKSENRYSVL------SVDSV 2055
Query 2040 ACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAA 2098
+ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2056 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2115
Query 2099 YVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTN 2155
Y+ + NELSR++ T+ +G+ + ++P D + N+ +
Sbjct 2116 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRDD---NQTLLVPKI 2171
Query 2156 IVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASF 2215
R + ++ + F + L FT T IA ++ L+ +F
Sbjct 2172 FKARAIEFY--GFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAF 2225
Query 2216 NYLKSPNFSKLINII-----IWF--LLLSVCLGSL---------IYSTAALGVLMSNLGM 2259
+ F K ++ WF L ++V I+ + + + G+
Sbjct 2226 QTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGL 2285
Query 2260 PSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISS---FKW 2316
+ C Y + + T + +C GS C +C SG D LDTY +++ +Q + F +
Sbjct 2286 VTICDFYSKLGVGFT----SHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDY 2341
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2342 -VSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2400
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2401 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2460
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2461 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2520
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + S + ++
Sbjct 2521 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVE--SDADRANF 2578
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2579 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQIMFDVYVDTFMSHFDVDRKSFNNFVN 2638
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2639 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2698
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK NI+ IW + F L+ L+ +++ A
Sbjct 2699 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKVANISCIWFIDAFNQLTADLQHKLKKAC 2758
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L ++L+ + + + P
Sbjct 2759 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPT 2815
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGS--YTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ GS Y N C
Sbjct 2816 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDC 2875
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2876 PIVVAVMDEDIGSTMFNVPTKVLRY-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2934
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2935 GCVLSSLCTMFKRGDGTPHPYCYTDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 2994
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 2995 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDFFDLFYQF 3054
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3055 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFL 3114
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3115 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3174
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N S STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3175 NHVLWLFS--YCRKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3230
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3231 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3290
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R + +F
Sbjct 3291 VSPTSKIEPCLVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDF 3350
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3351 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAF 3410
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3411 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFNGNFYGPYR 3470
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM + + D
Sbjct 3471 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADL 3530
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3531 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3587
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3588 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3646
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3647 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYEVFYGCIL 3706
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3707 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3762
Query 3749 TTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3763 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3822
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3823 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKC 3882
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD- 3926
+VVLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL S AVD
Sbjct 3883 ANVVLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFSNPAAVDT 3942
Query 3927 -----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKL 3980
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L
Sbjct 3943 KCLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQL 4002
Query 3981 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4040
+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKL
Sbjct 4003 EKACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKL 4062
Query 4041 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQ 4100
DN ALN+I++NA GCVPL+ IP A L ++IPD + D TYA ++W IQ
Sbjct 4063 DNQALNSILDNAVKGCVPLSAIPALAANTLTIIIPDKQVFDKVVDNVYVTYAGSVWHIQT 4122
Query 4101 VVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGT 4158
V DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4123 VQDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGS 4178
Query 4159 -----TQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPC 4213
T C YYN GR V A+LSD+ LK+ + K DG + EL+PPC
Sbjct 4179 DINCNIPTQC-------YYNNVSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPC 4230
Query 4214 RFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFA 4273
+F KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+
Sbjct 4231 KFSIQDVKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFS 4290
Query 4274 VDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCH 4333
VD K Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR
Sbjct 4291 VDPKKTYLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRAR 4350
Query 4334 IDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQS 4393
++HP+ G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS
Sbjct 4351 VEHPDVDGICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SSVAVQS 4408
Query 4394 ADAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKD 4452
D +FLNRV G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D
Sbjct 4409 KDL-NFLNRVRGTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRID 4467
Query 4453 EDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLT 4512
+D N +D +FVVKR Y E+T Y L K C VA+HDFF F IDG VPHI R+ L+
Sbjct 4468 DDGNKLDKFFVVKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRRNLS 4527
Query 4513 KYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGE 4572
KYTM DL YALRHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG
Sbjct 4528 KYTMLDLCYALRHFDRNDCSILCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGP 4587
Query 4573 RVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSL 4632
+ALL TV F D + G+VGVLTLDNQDL G WYDFGDFIQT PG GV V DSYYS
Sbjct 4588 IFNRALLNTVIFADTLVEVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSY 4647
Query 4633 LMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVN 4692
+MP+LT+ L E V+ Y ++DL++YDFT+ +L+LF++YFKYW YHPN V+
Sbjct 4648 MMPMLTMCHVLDCELFVN----DSYRQFDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVD 4703
Query 4693 CLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVN 4752
C +DRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+
Sbjct 4704 CDNDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVD 4763
Query 4753 LHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFY 4812
H RLS K+LL+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY
Sbjct 4764 THRYRLSLKDLLLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFY 4823
Query 4813 DFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF 4872
+F SKG FKEGS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF
Sbjct 4824 EFVKSKGLFKEGSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYF 4883
Query 4873 DCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTIT 4932
+ YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+T
Sbjct 4884 EIYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLT 4943
Query 4933 QMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHN 4992
QMNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +
Sbjct 4944 QMNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDD 5003
Query 4993 MLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECA 5052
ML+ + DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS RFYRLANECA
Sbjct 5004 MLRHLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECA 5063
Query 5053 QVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYV 5112
QVLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +
Sbjct 5064 QVLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSI 5123
Query 5113 RNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIK 5172
RNLQ RLY +YR VD FVNE+Y +L KHFSMMILSDD VVC+NS YA++G +A+I
Sbjct 5124 RNLQKRLYSNVYRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYANKGYIANIS 5183
Query 5173 NFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGA 5232
F+ VLYYQNNVFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGA
Sbjct 5184 AFQQVLYYQNNVFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGA 5243
Query 5233 GCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHML 5292
GCFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +L
Sbjct 5244 GCFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNDLGTQIL 5303
Query 5293 DMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCK 5352
D YSV+L+ + ++ E FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCK
Sbjct 5304 DSYSVILSTCDGLKFTEESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCK 5363
Query 5353 CCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQ 5412
CCYDHV++T+HK VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG
Sbjct 5364 CCYDHVMATNHKYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGM 5423
Query 5413 VFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLS 5472
VFGLYK +C GS + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK S
Sbjct 5424 VFGLYKQSCTGSPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQS 5483
Query 5473 YGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDA 5532
Y AT++E++SDRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + +
Sbjct 5484 YASATIQEIVSDREVILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNG 5543
Query 5533 VVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNV 5590
V YR TTTYKL++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y ++ F +NV
Sbjct 5544 VYYRATTTYKLSIGDVFVLTSHSVASLSAPTLVPQENYASIRFSSVY---SVPLVFQNNV 5600
Query 5591 ANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLP 5650
ANYQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L
Sbjct 5601 ANYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLN 5660
Query 5651 IDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSV 5710
I+ C+RIIPA+ RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV
Sbjct 5661 INDCTRIIPAKVRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSV 5720
Query 5711 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5770
+NAR++AKHYVYIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP
Sbjct 5721 INARIKAKHYVYIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPK 5780
Query 5771 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5830
EIV+TVSALVYDNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W
Sbjct 5781 EIVETVSALVYDNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVW 5840
Query 5831 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAIT 5890
AVFISPYNSQN VA ++LG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAIT
Sbjct 5841 NSAVFISPYNSQNYVAKRVLGVQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAIT 5900
Query 5891 RAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKVITGLHPTQAP 5949
RAK GI C+MS+ L++ L F +L + + TL + T LFKDCSK G HP AP
Sbjct 5901 RAKKGIFCVMSNMQLFESLNFITLPLDKIQNQTLPRLHCTTNLFKDCSKSCLGYHPAHAP 5960
Query 5950 THLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHV 6008
+ L+VD K+K E L V++ +TY RLIS+MGFK++ ++GY +FIT++EAI+ V
Sbjct 5961 SFLAVDDKYKVNENLAVNLNICEPVLTYSRLISLMGFKLDLTLDGYSKLFITKDEAIKRV 6020
Query 6009 RAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPG 6068
R W+GFDVEG HATRE +GTN PLQ+GFSTGV+ V TG + F + AK PPG
Sbjct 6021 RGWVGFDVEGAHATRENIGTNFPLQIGFSTGVDFVVEATGLFAERDCYTFKKTVAKAPPG 6080
Query 6069 DQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGP 6128
++FKHLIPLM KG W++VRI+IVQMLSD L +LSD VVF+ W+ FELT ++YF K+G
Sbjct 6081 EKFKHLIPLMSKGQKWDIVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGR 6140
Query 6129 ERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQV 6188
E C +C RATC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD+ C V
Sbjct 6141 ELNCNVCSNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNV 6200
Query 6189 HGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLA 6248
H AHVAS DAIMTRCLA+++CF K V+W +EYPII +E+ IN +CR +Q +++KAA+L
Sbjct 6201 HKGAHVASADAIMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLC 6260
Query 6249 DKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCL 6308
+++ + +DIGNPK + CV D E+KFYDA P A +++LFY Y H D F DG+C+
Sbjct 6261 NRYNLCYDIGNPKGLACVK--DYEFKFYDAFPV---AKSVKQLFYVYDVHKDNFKDGLCM 6315
Query 6309 FWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLP 6368
FWNCNVD+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +P
Sbjct 6316 FWNCNVDKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMP 6375
Query 6369 FFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMIS 6428
FFYYSD+PC +DYVPL+SATCITRCNLGGAVC HA EY YL++YN++ +
Sbjct 6376 FFYYSDTPCVYVDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEEYCNYLESYNIVTT 6435
Query 6429 AGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVD 6488
AGF+ WVYK FD YNLWNTFT LQSLENV +N+VN GH+DG+ GE+P +I+N+ V K++
Sbjct 6436 AGFTFWVYKTFDFYNLWNTFTTLQSLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKIN 6495
Query 6489 GVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHI 6548
VD +F+N T+ P N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +D+
Sbjct 6496 NVDTVIFKNNTSFPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCS 6555
Query 6549 STIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVG 6608
ST GVC TD+ K E L + FDGR G ++ FR ARNGV I+ + L G
Sbjct 6556 STYGVCKYTDL--KFIEN----LNILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKG 6609
Query 6609 PKQASLNGVTL--IGEAVKTQFNYYKKVDG--VVQQLPE--------------------- 6643
P++A LNGV + +GE +K +F + + DG V+ +
Sbjct 6610 PQRADLNGVIVDKVGE-LKVEFWFAMRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGN 6668
Query 6644 ----------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFS 6693
T FTQSR L F+PRS +E DF+++ + FI +Y LE YAF+HIVYG F+
Sbjct 6669 VIGNDALTRFTIFTQSRVLSSFEPRSDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFN 6728
Query 6694 HSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDD 6753
H +GGLHLLIGL +R K+S +++F+ DS++ +YFITD + GSSK VC+VIDLLLDD
Sbjct 6729 HKVIGGLHLLIGLFRRLKKSNLLIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDD 6788
Query 6754 FVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLY 6813
FV I+KS +LS VSKVV + +D+ + FMLWC D + TFYPK+Q++ W+PG +MP LY
Sbjct 6789 FVSIVKSLNLSCVSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATNDWKPGYSMPVLY 6848
Query 6814 KMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSD 6873
K + LE+ L NYG LP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSD
Sbjct 6849 KYLNVPLERVSLWNYGKPINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSD 6908
Query 6874 KGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPK 6933
K VAPG+AVLRQWLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP
Sbjct 6909 KEVAPGSAVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPL 6968
Query 6934 TKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVT 6993
TKN+ N SK+GFFTYIC I+ KL+LGGSVAIKITE SWNADLYKLM FA+WT F T
Sbjct 6969 TKNIGDYNVSKDGFFTYICHLIRDKLSLGGSVAIKITEFSWNADLYKLMSCFAFWTVFCT 7028
Query 6994 NVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLR 7053
NVNASSSE FLIG NYLGK +IDG VMHANY+FWRN+ +YSLFDM+KF LKL
Sbjct 7029 NVNASSSEGFLIGINYLGKSSFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMTKFSLKLA 7088
Query 7054 GTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
GTAV++L+ Q+ND++ SL+ +G+L++R+ + + D LVN
Sbjct 7089 GTAVVNLRPDQLNDLVYSLIERGKLLVRDTRKEIFVGDSLVN 7130
Score = 82.0 bits (201), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 53/155 (34%), Positives = 79/155 (51%), Gaps = 2/155 (1%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A E+ +
Sbjct 1308 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1367
Query 1092 ATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHEVLLAPLL 1149
+ G +VG V +G L K L++VGP+ + + LL AY++ N ++ L+ L+
Sbjct 1368 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1427
Query 1150 SAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
SAGIF SL + V V L +K +D
Sbjct 1428 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFD 1462
Score = 74.3 bits (181), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 103/422 (24%), Positives = 171/422 (41%), Gaps = 63/422 (15%)
Query 562 LQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW-------- 612
L ++ I +SQ+S + D + L + + V YI V +L +Q+
Sbjct 562 LIQSGIFFTSLMSQFSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLV 621
Query 613 --LTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKE 670
+ N F T+ + P WL + G F+ + A I AK
Sbjct 622 NKMVNWFNTMLDASAPATGWLLYQLLNGF-----------FVVSQANLNFVALIPDYAKI 670
Query 671 IKESVQTFFKLVNKFLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSRE 725
+ TFFKL+ L ++ LK +N +G F S GL
Sbjct 671 LVNKFYTFFKLL---LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI-------- 719
Query 726 ETGLLMPLKA-PKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTP 782
G ++P A ++I F EG + E V+++ ++ ++ S E + P
Sbjct 720 -PGFVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEK 771
Query 783 VCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGG-----APTKVTFGDDTVI-EVQGY 836
+CI M + K +K+ P +M N L A KV F + V+ E+
Sbjct 772 ICIIDNMYMG-KCGDKF---FPIVMNDKNICLLDHAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 837 KSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPL 893
+V + F+LD D +L + CS + VE G V++F VV DA+ L E + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQV 887
Query 894 GIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTE 952
L++ + YLFDE+G+ +AS MYC+F D ED + E+ + + +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 953 DD 954
+D
Sbjct 948 ED 949
Score = 44.3 bits (103), Expect = 0.064, Method: Compositional matrix adjust.
Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 16/148 (11%)
Query 1658 YPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAY 1717
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1095 YFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTT 1154
Query 1718 CNKTV--GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
K + + G V + + ++++ N C CG L G++AV + G +
Sbjct 1155 IPKAIVLPQGGYVADFAYWFLNQFDINA---YANWCCLKCG-FSFDLNGLDAVFFYGDI- 1209
Query 1776 YEQFKKGVQIPCTCGKQATKYLVQQESP 1803
V C CG T L+ + P
Sbjct 1210 -------VSHVCKCGHNMT--LIAADLP 1228
>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182
Score = 5337 bits (13845), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2744/5617 (49%), Positives = 3662/5617 (65%), Gaps = 173/5617 (3%)
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1650 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1709
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1710 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1768
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1769 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1828
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF+
Sbjct 1829 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPFL 1886
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ + G GHY H+ D + K + G +TD
Sbjct 1887 ICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLTD 1944
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--N 1922
Y +N + T T Y LD V +P L YY + Y+T +PI +P+ +
Sbjct 1945 CLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKVD 2003
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I LN G+ E KVT +P GDVV Y + K
Sbjct 2004 GVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2061
Query 1982 GAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNL 2039
G + KP++W H + N TY ++ ++ N + VL +D++
Sbjct 2062 GCETFGKPVIWFCHDEASLNSLTY----------FNKPSFKSENRYSVL------SVDSV 2105
Query 2040 ACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAA 2098
+ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2106 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2165
Query 2099 YVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTN 2155
Y+ + NELSR++ T+ +G+ + ++P D + N+ +
Sbjct 2166 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRDD---NQTLLVPKI 2221
Query 2156 IVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASF 2215
R + ++ + F + L FT T IA ++ L+ +F
Sbjct 2222 FKARAIEFY--GFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAF 2275
Query 2216 NYLKSPNFSKLINII-----IWF--LLLSVCLGSL---------IYSTAALGVLMSNLGM 2259
+ F K ++ WF L ++V I+ + + + G+
Sbjct 2276 QTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGL 2335
Query 2260 PSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISS---FKW 2316
+ C Y + + T + +C GS C +C SG D LDTY +++ +Q + F +
Sbjct 2336 VTICDFYSKLGVGFT----SHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDY 2391
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2392 -VSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2450
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2451 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2510
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2511 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2570
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + S + ++
Sbjct 2571 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVE--SDADRANF 2628
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2629 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVN 2688
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2689 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2748
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK+ NI+ IW + F L+ L+ +++ A
Sbjct 2749 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDAFNQLTADLQHKLKKAC 2808
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L V+L+ + + + P
Sbjct 2809 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFVSLICFI---LLWALLPT 2865
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGS--YTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ GS Y N C
Sbjct 2866 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDC 2925
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2926 PIVVAVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2984
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2985 GCVLSSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 3044
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 3045 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQF 3104
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3105 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVVVWCINFL 3164
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3165 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3224
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N S STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3225 NHVLWLFS--YCRKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3280
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3281 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3340
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC+S +M P+Y LL R + +F
Sbjct 3341 VSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICSSSNMNEPDYSALLCRVTLGDF 3400
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3401 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGNVKPGETFTVLAAYNGRPQGAF 3460
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3461 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYR 3520
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ + DFN+ AM + + D
Sbjct 3521 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSTEDFNVWAMANGFSQVKADL 3580
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3581 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3637
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3638 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3696
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3697 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSYFVPAVNFTYVYEVFYGCIL 3756
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3757 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3812
Query 3749 TTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3813 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3872
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3873 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKC 3932
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD- 3926
+VVLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3933 ANVVLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDT 3992
Query 3927 -----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKL 3980
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L
Sbjct 3993 KCLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQL 4052
Query 3981 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4040
+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKL
Sbjct 4053 EKACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKL 4112
Query 4041 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQ 4100
DN ALN+I++NA GCVPL+ IP A L +VIPD + D TYA ++W IQ
Sbjct 4113 DNQALNSILDNAVKGCVPLSAIPALAANTLTIVIPDKQVFDKVVDNVYVTYAGSVWHIQT 4172
Query 4101 VVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGT 4158
V DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4173 VQDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGS 4228
Query 4159 TQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTD 4218
+ YYN GR V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4229 DMNC--NIPTQCYYNNGSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFSIQ 4285
Query 4219 TPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK 4278
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VD K
Sbjct 4286 DVKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKK 4345
Query 4279 AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPN 4338
Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+
Sbjct 4346 TYLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPD 4405
Query 4339 PKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQS 4398
G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D +
Sbjct 4406 VDGICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SSVAVQSKDL-N 4462
Query 4399 FLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNL 4457
FLNRV G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D+D N
Sbjct 4463 FLNRVRGTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRIDDDGNK 4522
Query 4458 IDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMA 4517
+D +FVVKR Y E+T Y L K C VA+HDFF F IDG VPHI R+ L+KYTM
Sbjct 4523 LDKFFVVKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRRNLSKYTML 4582
Query 4518 DLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQA 4577
DL YALRHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG +A
Sbjct 4583 DLCYALRHFDRNDCSILCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGPIFNRA 4642
Query 4578 LLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPIL 4637
LL TV F D + G+VGVLTLDNQDL G WYDFGDFIQT PG GV V DSYYS +MP+L
Sbjct 4643 LLNTVIFADTLVEVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSYMMPML 4702
Query 4638 TLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDR 4697
T+ L E V+ Y ++DL++YDFT+ +L+LF++YFKYW YHPN V+C +DR
Sbjct 4703 TMCHVLDCELFVN----DSYRQFDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVDCDNDR 4758
Query 4698 CILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSR 4757
CI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H R
Sbjct 4759 CIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVDTHRYR 4818
Query 4758 LSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVS 4817
LS K+LL+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY+F S
Sbjct 4819 LSLKDLLLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFYEFVKS 4878
Query 4818 KGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDG 4877
KG FKEGS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDG
Sbjct 4879 KGLFKEGSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDG 4938
Query 4878 GCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLK 4937
GCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+TQMNLK
Sbjct 4939 GCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLTQMNLK 4998
Query 4938 YAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTV 4997
YAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ +
Sbjct 4999 YAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRHL 5058
Query 4998 YSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSE 5057
DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS RFYRLANECAQVLSE
Sbjct 5059 IKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECAQVLSE 5118
Query 5058 MVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQH 5117
+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +RNLQ
Sbjct 5119 IVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSIRNLQK 5178
Query 5118 RLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSV 5177
RLY +YR VD FVNE+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I F+ V
Sbjct 5179 RLYSNVYRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYASKGYIANISVFQQV 5238
Query 5178 LYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVD 5237
LYYQNNVFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGAGCFVD
Sbjct 5239 LYYQNNVFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGAGCFVD 5298
Query 5238 DIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSV 5297
D++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD YSV
Sbjct 5299 DLLKTDSVLLIERFVSLAIDAYPLVHHENEEYQKVFRVYLEYIKKLYNDLGTQILDSYSV 5358
Query 5298 MLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDH 5357
+L+ + ++ E FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDH
Sbjct 5359 ILSTCDGLKFTEESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDH 5418
Query 5358 VISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLY 5417
V++T+HK VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG VFGLY
Sbjct 5419 VMATNHKYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGMVFGLY 5478
Query 5418 KNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIAT 5477
K +C GS + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK SY AT
Sbjct 5479 KQSCTGSPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQSYASAT 5538
Query 5478 VREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRG 5537
++E++SDRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + + V YR
Sbjct 5539 IQEIVSDREVILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNGVYYRA 5598
Query 5538 TTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQK 5595
TTTYKL++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y ++ F +NVANYQ
Sbjct 5599 TTTYKLSIGDVFVLTSHSVASLSAPTLVPQENYASIRFSSVY---SVPLVFQNNVANYQH 5655
Query 5596 VGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS 5655
+GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+
Sbjct 5656 IGMKRYCTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLNINDCT 5715
Query 5656 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5715
RIIPA+ RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NAR+
Sbjct 5716 RIIPAKVRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSVINARI 5775
Query 5716 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5775
+AKHYVYIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP EIV+T
Sbjct 5776 KAKHYVYIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPKEIVET 5835
Query 5776 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVF 5835
VSALVYDNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W AVF
Sbjct 5836 VSALVYDNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVWNSAVF 5895
Query 5836 ISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVG 5895
ISPYNSQN VA ++LG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK G
Sbjct 5896 ISPYNSQNYVAKRVLGVQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKG 5955
Query 5896 ILCIMSDRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKVITGLHPTQAPTHLSV 5954
I C+MS+ L++ L F +L + + TL + T LFKDCSK G HP AP+ L+V
Sbjct 5956 IFCVMSNMQLFESLNFITLPLDKIQNQTLPRLHCTTNLFKDCSKSCLGYHPAHAPSFLAV 6015
Query 5955 DTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIG 6013
D K+K E L V++ +TY RLIS+MGFK++ ++GY +FIT++EAI+ VR W+G
Sbjct 6016 DDKYKVNENLAVNLNICEPVLTYSRLISLMGFKLDLTLDGYSKLFITKDEAIKRVRGWVG 6075
Query 6014 FDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKH 6073
FDVEG HATRE +GTN PLQ+GFSTGV+ V TG + F + AK PPG++FKH
Sbjct 6076 FDVEGAHATRENIGTNFPLQIGFSTGVDFVVEATGLFAERDCYTFKKTVAKAPPGEKFKH 6135
Query 6074 LIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCC 6133
LIPLM KG W++VRI+IVQMLSD L +LSD VVF+ W+ FELT ++YF K+G E C
Sbjct 6136 LIPLMSKGQKWDIVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGRELNCN 6195
Query 6134 LCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAH 6193
+C RATC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD+ C VH AH
Sbjct 6196 VCSNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNVHKGAH 6255
Query 6194 VASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPV 6253
VAS DAIMTRCLA+++CF K V+W +EYPII +E+ IN +CR +Q +++KAA+L +++ +
Sbjct 6256 VASADAIMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLCNRYNL 6315
Query 6254 LHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCN 6313
+DIGNPK + CV D E+KFYDA P A +++LFY Y H D F DG+C+FWNCN
Sbjct 6316 CYDIGNPKGLACVK--DYEFKFYDAFPV---AKSVKQLFYVYDVHKDNFKDGLCMFWNCN 6370
Query 6314 VDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYS 6373
VD+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +PFFYYS
Sbjct 6371 VDKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMPFFYYS 6430
Query 6374 DSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSL 6433
D+PC +DYVPL+SATCITRCNLGGAVC HA EY YL++YN++ +AGF+
Sbjct 6431 DTPCVYVDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEEYCNYLESYNIVTTAGFTF 6490
Query 6434 WVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVE 6493
WVYK FD YNLWNTFT LQSLENV +N+VN GH+DG+ GE+P +I+N+ V K++ VD
Sbjct 6491 WVYKNFDFYNLWNTFTTLQSLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKINNVDTV 6550
Query 6494 LFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGV 6553
+F+N T+ P N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +D+ ST GV
Sbjct 6551 IFKNNTSFPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGV 6610
Query 6554 CSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQAS 6613
C TD+ K E L + FDGR G ++ FR ARNGV I+ + L GP++A
Sbjct 6611 CKYTDL--KFIEN----LNILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKGPQRAD 6664
Query 6614 LNGVTL--IGEAVKTQFNYYKKVDG--VVQQLPE-------------------------- 6643
LNGV + +GE +K +F + + DG V+ +
Sbjct 6665 LNGVIVDKVGE-LKVEFWFAMRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGNVIGND 6723
Query 6644 -----TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLG 6698
T FTQSR L F+PRS +E DF+++ + FI +Y LE YAF+HIVYG F+H +G
Sbjct 6724 ALTRFTIFTQSRVLSSFEPRSDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFNHKVIG 6783
Query 6699 GLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEII 6758
GLHLLIGL +R K+S +++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+
Sbjct 6784 GLHLLIGLFRRKKKSNLLIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVSIV 6843
Query 6759 KSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRM 6818
KS +LS VSKVV + +D+ + FMLWC D + TFYPK+Q++ W+PG +MP LYK +
Sbjct 6844 KSLNLSCVSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATNDWKPGYSMPVLYKYLNV 6903
Query 6819 LLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAP 6878
LE+ L NYG LP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAP
Sbjct 6904 PLERVSLWNYGKPINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSDKEVAP 6963
Query 6879 GTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVT 6938
G+AVLRQWLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP TKN+
Sbjct 6964 GSAVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPLTKNIG 7023
Query 6939 KENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNAS 6998
N SK+GFFTYIC I+ KL+LGGSVAIKITE SWNADLYKLM FA+WT F TNVNAS
Sbjct 7024 DYNVSKDGFFTYICHLIRDKLSLGGSVAIKITEFSWNADLYKLMSCFAFWTVFCTNVNAS 7083
Query 6999 SSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVM 7058
SSE FLIG NYLGK +IDG VMHANY+FWRN+ +YSLFDM+KF LKL GTAV+
Sbjct 7084 SSEGFLIGINYLGKSSFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMTKFSLKLAGTAVV 7143
Query 7059 SLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
+L+ Q+ND++ SL+ +G+L++R+ + + D LVN
Sbjct 7144 NLRPDQLNDLVYSLIERGKLLVRDTRKEIFVGDSLVN 7180
Score = 81.6 bits (200), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 53/155 (34%), Positives = 79/155 (51%), Gaps = 2/155 (1%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A E+ +
Sbjct 1358 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1417
Query 1092 ATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHEVLLAPLL 1149
+ G +VG V +G L K L++VGP+ + + LL AY++ N ++ L+ L+
Sbjct 1418 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1477
Query 1150 SAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
SAGIF SL + V V L +K +D
Sbjct 1478 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFD 1512
Score = 75.1 bits (183), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 103/422 (24%), Positives = 172/422 (41%), Gaps = 63/422 (15%)
Query 562 LQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW-------- 612
L ++ I +SQ+S + D + L + + V YI V +L +Q+
Sbjct 562 LIQSGIFFTSLMSQFSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLV 621
Query 613 --LTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKE 670
+ N F T+ + P WL + G+ F+ + A I AK
Sbjct 622 NKMVNWFNTMLDASAPATGWLLYQLLNGL-----------FVVSQANFNFVALIPDYAKI 670
Query 671 IKESVQTFFKLVNKFLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSRE 725
+ TFFKL+ L ++ LK +N +G F S GL
Sbjct 671 LVNKFYTFFKLL---LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI-------- 719
Query 726 ETGLLMPLKA-PKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTP 782
G ++P A ++I F EG + E V+++ ++ ++ S E + P
Sbjct 720 -PGFVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEK 771
Query 783 VCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGG-----APTKVTFGDDTVI-EVQGY 836
+CI M + K +K+ P +M N L A KV F + V+ E+
Sbjct 772 ICIIDNMYMG-KCGDKF---FPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 837 KSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPL 893
+V + F+LD D +L + CS + VE G V++F VV DA+ L E + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQV 887
Query 894 GIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTE 952
L++ + YLFDE+G+ +AS MYC+F D ED + E+ + + +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 953 DD 954
+D
Sbjct 948 ED 949
Score = 43.1 bits (100), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 36/148 (24%), Positives = 64/148 (43%), Gaps = 16/148 (11%)
Query 1658 YPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAY 1717
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1145 YFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTT 1204
Query 1718 CNKTV--GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
K + + G V + + ++++ N C CG L G++A+ + G +
Sbjct 1205 IPKAIVLPQGGFVADFAYWFLNQFDINA---YANWCCLKCG-FSFDLNGLDALFFYGDI- 1259
Query 1776 YEQFKKGVQIPCTCGKQATKYLVQQESP 1803
V C CG T L+ + P
Sbjct 1260 -------VSHVCKCGHNMT--LIAADLP 1278
>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180
Score = 5337 bits (13844), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2744/5655 (49%), Positives = 3663/5655 (65%), Gaps = 213/5655 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ V TVD +N + V +G+ G + DG +VTK++ H+GK F+
Sbjct 1610 VDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIHKGKVFFQYSGLSAA 1669
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
+ A + D L +Y S L K W + K ++NNCY+ A L LQ +
Sbjct 1670 DLAAVKDAFGFDEPQLLQYYSMLGMCK-WPVVVCGNYFAFKQSNNNCYINVACLMLQHLS 1728
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF + R+G+ F +L+LA + E D + + + A+L
Sbjct 1729 LKFPKWQWRRPGNEFRSGKPLRFVSLVLAKGSFKFNEPSDSTDFIRVELREADLSGATCD 1788
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
L +CK CG +Q KGV+AVM+ GTL KG I CTCG + + Q PF++
Sbjct 1789 LEFICK-CGVKQEQRKGVDAVMHFGTLDKSGLVKGYNIACTCGDKLV-HCTQFNVPFLIC 1846
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S P +L A+ +TG GHY H+ K D ++K SE KG TD
Sbjct 1847 SNTPEGKKLPDDVVA-ANIFTGG-SVGHYTHVKCKPKYQLYDACNVSKVSEAKGNFTDCL 1904
Query 1868 YKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPNAS-- 1924
Y +N T + TY LD V C P L YY + Y+T +PI + +
Sbjct 1905 YLKNLKQTFSSVLTTYYLDDVKCVAYKPDLSQYYCESGKYYT-KPIIKAQFRTFEKVEGV 1963
Query 1925 FDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK V +I A+ LN G+ E K+T +P GDVV Y + G
Sbjct 1964 YTNFKLVGHDI--AEKLNAKLGFDCNSPFMEYKITEWPTATGDVVLASDDLYVSRYSGGC 2021
Query 1984 KLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVETSNSFD------------- 2026
KP++W H + TY +P+ C ++ PV+ S D
Sbjct 2022 VTFGKPVIWRGHEEASLKSLTYFNRPSVVC-ENKFNVLPVDVSEPTDRRPVPSAVLVTGA 2080
Query 2027 -------VLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVG------ 2073
+ +E + AC V +++V + V VK ++ G
Sbjct 2081 ASGADASAISTEPGTAKEQKACAS-DSVEDQIVMEAQKKSSVTTVAVKEVKLNGVKKPVK 2139
Query 2074 ---DIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATH---GL 2127
+++ + K+ + + D+ ++ + NELSR++ T+ + G+
Sbjct 2140 WNCSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWTANELSRLINSPTVREYVKWGM 2199
Query 2128 AAVNSVPWDTI--ANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRS 2185
+ + +P + + + + F+ V I C + +F F
Sbjct 2200 SKL-IIPANLLLLRDEKQEFVAPKVVKAKAIA-------CYGAVKWFLLYCFSWIKF--- 2248
Query 2186 TNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLIN--------IIIWF--LL 2235
N+ K T +A K K C A N L++ N+S + ++WF L
Sbjct 2249 -NTDNKVIYTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVFLLWFNFLY 2304
Query 2236 LSVCLGSL---------IYSTAALGVLMSNLGMPSYCTGYRE---GYLNSTNVTIATYCT 2283
+V L ++ + + + G+ + C Y+ GY +S +C
Sbjct 2305 ANVILSDFYLPNIGPLPMFVGQIVAWVKTTFGVLTICDFYQVTDLGYRSS-------FCN 2357
Query 2284 GSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
GS+ C +C SG D LD Y S+ +Q + SF + ++ F LV E + Y L+T FY
Sbjct 2358 GSMVCELCFSGFDMLDNYESINVVQHVVDRRVSFDY-ISLFKLVVELVIGYSLYTVCFYP 2416
Query 2341 LGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYV 2398
L + MQL ++ F+ + W L + + M P ++R YI + Y V+
Sbjct 2417 LFVLVGMQLLTTWLPEFFMLGTMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVYCLCR 2476
Query 2399 HVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTF 2458
HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC+NC+++
Sbjct 2477 HVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLNCNSW 2536
Query 2459 CAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSL 2518
G+TFI+ E A DLS + KRP+NPTD + Y V V S+ L++++ GQ+ Y+ S
Sbjct 2537 KPGNTFITHEAAADLSKELKRPVNPTDSAYYSVIEVKQVGCSMRLFYERDGQRVYDDVSA 2596
Query 2519 SHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVS 2578
S FV+++ L + KG +V+V + ++ +++ +A+V+Y+Q + +P+L++++ L++
Sbjct 2597 SLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRPMLMVEKKLIT 2654
Query 2579 DVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAAR 2638
V+ MFD YV + +V + L + V A L + V L+ V+ TF+ AR
Sbjct 2655 TANTGLSVSRTMFDLYVYSLLRHLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFVGCAR 2714
Query 2639 QG-FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSAR 2697
+ +DSDVETK + + + + + +EVT +SCNN + TY K + + DLG I +A+
Sbjct 2715 RKCAIDSDVETKSITKSVMAAVNAGVEVTDESCNNLVPTYVKSDTIVAADLGVLIQNNAK 2774
Query 2698 HINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTK 2757
H+ + VAK+ N+A IW+V F LS L+ ++R A K L KLT V ++TT
Sbjct 2775 HVQSNVAKAANVACIWSVDAFNQLSADLQHRLRKACVKTGLKIKLTYNKQEANVPILTTP 2834
Query 2758 IALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVT 2817
+LKGG + + L+ L L+ V + + P + + K +K ID GV
Sbjct 2835 FSLKGGAVFSRVLQWLFVANLICFIV---LWALMPTYAVHKSDMQLPLYASFKVIDNGVL 2891
Query 2818 RDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILR 2875
RD++ TD CFANK FD W+ G Y N KACP++ AVI +++G + +P +LR
Sbjct 2892 RDVSVTDACFANKFNQFDQWYESTFGLVYYRNSKACPVVVAVIDQDIGHTLFNVPTKVLR 2951
Query 2876 TTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYD 2935
LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P PYCY
Sbjct 2952 Y-GFHVLHFITHAFATDRVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHPYCYT 3010
Query 2936 TNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEA 2994
V+ + Y SL P RY L + I+FP EG VRVV T YCR G CE +E
Sbjct 3011 EGVMHNASLYSSLVPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLCEEAEE 3070
Query 2995 GVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVA 3054
G+C + + WVLNN YYR++PG FCG +A +L+ + L+QPI ++AS VAG I+A
Sbjct 3071 GICFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVQPIDFFALTASSVAGAILA 3130
Query 3055 IVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTF 3114
I+V YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L +Y+ Y Y T
Sbjct 3131 IIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFYTTL 3190
Query 3115 YLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFST 3174
Y +++S + H+QW+VM+ ++P W I Y+ + + H W FS R++ + S T
Sbjct 3191 YFPSEISVVMHLQWLVMYGAIMPLWFCITYVAVVVSNHALWLFS--YCRKIGTDVRSDGT 3248
Query 3175 FEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL 3234
FEE AL TF++ KE Y KL++ V +NRYL+LYNKY+YFSG MDT +YREAAC L
Sbjct 3249 FEEMALTTFMITKESYCKLKNSV--SDVAFNRYLSLYNKYRYFSGKMDTATYREAACSQL 3306
Query 3235 AKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
AKA+ F+ N+G+DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G TLNGL
Sbjct 3307 AKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCVVSVTYGNMTLNGL 3366
Query 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
WLDD VYCPRHVIC+S DM +P+Y +LL R ++ +F V + + L V+ + MQ +L L
Sbjct 3367 WLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSDRMSLTVMSYQMQGSLLVLT 3426
Query 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
V NP TPKY F ++PG+TF+VLA YNG P G + MR + TIKGSFL GSCGSVG+
Sbjct 3427 VTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVVMRSSHTIKGSFLCGSCGSVGY 3486
Query 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
+ D V F YMH +EL TG H GTD GNFYGP+ D Q Q D T TVNV+AWLYA
Sbjct 3487 VLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAWLYA 3546
Query 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
A++N WF+ + +L +FN+ AM + + D V L L++ TG+ V + A++K
Sbjct 3547 AILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVLAAIKR 3604
Query 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
L +G G+ ILGS +LEDE TP DV +Q +GV QS R IKGT W+L + +
Sbjct 3605 L-HSGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTFLFCSI 3663
Query 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
+ +W++F ++ + L + + FAM+ +KHKH +L ++++P L T+ Y N +
Sbjct 3664 ISAFVKWTMFMYVTTH-MLGVTLCALCFVIFAMLLIKHKHLYLTMYIMPVLCTLFYTNYL 3722
Query 3654 YMPASWVMRIMT--WLDMVDTSLSGFKLKDCVMYASAVVLLILM---TARTVYDDGARRV 3708
+ R + WL ++ + D V+Y VVLL+ M T R++ D +
Sbjct 3723 VVGYKQSFRGLAYAWLSYFVPAVD-YTYMDEVLYG--VVLLVAMVFVTMRSINHDVFSTM 3779
Query 3709 WTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARG-IVFMCVEYCP 3767
+ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA ++ +
Sbjct 3780 FLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKWLAVNV 3835
Query 3768 IFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQG 3827
++F ++ ++L Y +GY C CY+G+ LLN FR+ LGVY+Y +S QE RYMN+ G
Sbjct 3836 LYFTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISVQELRYMNANG 3895
Query 3828 LLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKL 3887
L PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+SKL
Sbjct 3896 LRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNSKL 3955
Query 3888 WAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATL 3941
W C LHN+IL D + AF+K+ LL VL + AVD I ++ ++ + + L
Sbjct 3956 WQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNTVL 4015
Query 3942 QAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRK 4000
QA+ SEF ++ S+ + A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ RK
Sbjct 4016 QALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARK 4075
Query 4001 LEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLN 4060
LE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN
Sbjct 4076 LERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLN 4135
Query 4061 IIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSP 4120
IP T+ L +++PD + D TYA +W IQ + DAD + QL+EI ++++
Sbjct 4136 AIPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDVNST- 4194
Query 4121 NLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGG 4178
WPL+++A R N S V LQNNEL P LR +G+ + YYNTT G
Sbjct 4195 ---WPLVISANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNC--NIPTQCYYNTTGTG 4249
Query 4179 RFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLN 4238
+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L
Sbjct 4250 KIVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNTLA 4308
Query 4239 RGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKML 4298
RG V+G+L++TVRLQAG ATE +NS +LS CAF+VD K Y DY+ GG P+TNCVKML
Sbjct 4309 RGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIQQGGVPVTNCVKML 4368
Query 4299 CTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCAN 4358
C H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P
Sbjct 4369 CDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-IK 4427
Query 4359 DPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTG 4417
DPV + L + VC VCG W+ CSC QS D +FLNRV G S ARL PC +G
Sbjct 4428 DPVSYVLTHDVCQVCGFWRDGSCSCVGTGS-QFQSKDT-NFLNRVRGTSVNARLVPCASG 4485
Query 4418 TSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEET 4477
TDV RAFDI N AG + K NC RFQ DE+ N +D +FVVKR Y E+
Sbjct 4486 LDTDVQLRAFDICNANRAGIGLYYKVNCFRFQRVDEEGNKLDKFFVVKRTNLEVYNKEKE 4545
Query 4478 IYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEI 4537
Y L KDC VA+H+FF F ++G VPHI R+ L+K+TM DL YALRHFD +C TLKEI
Sbjct 4546 CYELTKDCGVVAEHEFFTFDVEGSRVPHIVRKDLSKFTMLDLCYALRHFDRNDCSTLKEI 4605
Query 4538 LVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVL 4597
L+TY CD+ YF KKDWYDFVENPDI+ VY LG +ALL T F D + AG+VGVL
Sbjct 4606 LLTYAECDESYFQKKDWYDFVENPDIINVYKKLGPIFNRALLNTANFADTLVEAGLVGVL 4665
Query 4598 TLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPY 4657
TLDNQDL G WYDFGDF++T P GV V DSYYS +MP+LT+ AL +E V+ Y
Sbjct 4666 TLDNQDLYGQWYDFGDFVKTVPCCGVAVADSYYSYMMPMLTMCHALDSELFVN----GTY 4721
Query 4658 IKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTS 4717
++DL++YDFT+ +L+LF++YFK+W TYHPN C DDRCI+HCANFN+LFS V P T
Sbjct 4722 REFDLVQYDFTDFKLELFNKYFKHWSMTYHPNTSECEDDRCIIHCANFNILFSMVLPKTC 4781
Query 4718 FGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASG 4777
FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+LL+YAADPA+H AS
Sbjct 4782 FGPLVRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYRLSLKDLLLYAADPALHVASA 4841
Query 4778 NLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQD 4837
+ LLD RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +SKG KEGSSV+LKHFFF QD
Sbjct 4842 SALLDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSVDLKHFFFTQD 4901
Query 4838 GNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFP 4897
GNAAI+DY+YY+YNLPTM DI+QLLFVVEVV+KYF+ Y+GGCI A QVIVNN DKSAG+P
Sbjct 4902 GNAAITDYNYYKYNLPTMVDIKQLLFVVEVVNKYFEIYEGGCIPATQVIVNNYDKSAGYP 4961
Query 4898 FNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICST 4957
FNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI ST
Sbjct 4962 FNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILST 5021
Query 4958 MTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRA 5017
MT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPKCDRA
Sbjct 5022 MTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPKCDRA 5081
Query 5018 MPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDA 5077
MPN+LRI++SLVLARKH +CCS + RFYRLANECAQVL E+VMCGG YVKPGGTSSGDA
Sbjct 5082 MPNILRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLGEIVMCGGCYYVKPGGTSSGDA 5141
Query 5078 TTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEF 5137
TTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD FV+E+
Sbjct 5142 TTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVSEY 5201
Query 5138 YAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDL 5197
Y +L KHFSM+ILSDD VVC+NS +AS+G +A+I +F+ VLYYQNNVFMSEAKCW ETD+
Sbjct 5202 YEFLNKHFSMIILSDDGVVCYNSEFASKGYIANISDFQQVLYYQNNVFMSEAKCWVETDI 5261
Query 5198 TKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAID 5257
KGPHEFCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFVSLAID
Sbjct 5262 EKGPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFVSLAID 5321
Query 5258 AYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMY 5317
AYPL H N EY +VF +YL+YI+KL+++L +LD SV+L+ + ++ + FY+ MY
Sbjct 5322 AYPLVYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSISVILSTCDGQKFTDETFYKNMY 5381
Query 5318 TPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAP 5377
V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC YDHV+ST HK VLSV+PYVCN+P
Sbjct 5382 LRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVLSVSPYVCNSP 5441
Query 5378 GCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCD 5437
GCDV DVT+LYLGGMSYYC++HKP SF L NG VFGLYK +C GS + DFN IA+C
Sbjct 5442 GCDVNDVTKLYLGGMSYYCEAHKPQYSFKLVMNGMVFGLYKQSCTGSPYIEDFNKIASCK 5501
Query 5438 WTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPR 5497
WT DY+LAN CTERLKLFAAET KATEE FK Y AT+RE++SDREL LSWE+GK R
Sbjct 5502 WTEVDDYVLANECTERLKLFAAETQKATEEAFKQCYASATIREIVSDRELILSWEIGKVR 5561
Query 5498 PPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVM 5557
PPLN+NYVFTGY T N K +GEY F+K + + V YR TTTYKL+VGD F+LTSH V
Sbjct 5562 PPLNKNYVFTGYHFTNNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFILTSHAVS 5621
Query 5558 PLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHF 5615
LSAPTLVPQE+Y VR Y ++ + F +NV NYQ +G+++Y T+QGPPGTGKSH
Sbjct 5622 SLSAPTLVPQENYTSVRFASAY---SVPETFQNNVPNYQHIGIKRYCTVQGPPGTGKSHL 5678
Query 5616 AIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNST 5675
AIG A+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RV+C+DKF VN T
Sbjct 5679 AIGHAVYYCTARVVYTAASHAAVDALCEKAHKFLNINDCARIVPAKLRVDCYDKFNVNDT 5738
Query 5676 LEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTL 5735
+YVF T+NALPE DI+V DE+SM TNY+LSV+N+R+RAKHYVYIGDPAQLPAPR L
Sbjct 5739 TRKYVFTTINALPELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGDPAQLPAPRVL 5798
Query 5736 LTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQC 5795
L KGTLEP YFNSV +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA D SA C
Sbjct 5799 LNKGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYNNKLKAKNDNSAMC 5858
Query 5796 FKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQ 5855
FK++YKG TH+ SSA+N QI ++ + L NP+W AVFISPYNSQN VA ++LGL TQ
Sbjct 5859 FKVYYKGQTTHESSSAVNMQQIHLISKLLKANPSWSNAVFISPYNSQNYVAKRVLGLQTQ 5918
Query 5856 TVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLE 5915
T DS+QGS YD+VI++QT +TAHS NVNRFNVAITRAK GILC+MS L FT+L
Sbjct 5919 TADSAQGSAYDFVIYSQTAQTAHSVNVNRFNVAITRAKKGILCVMSSMQLIGVFNFTTLT 5978
Query 5916 IPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDM 5974
+ + N LQ T LFKDCSK G+ P L+VD K+K G L V + +
Sbjct 5979 LDKINNPRLQC--TTNLFKDCSKSYVGIPP--CAFLLAVDDKYKVSGNLAVCLNVADSAV 6034
Query 5975 TYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQL 6034
TY RLIS+MGFK++ ++GY +FITR+EAI+ VRAW+GFD EG HATR+++GTN PLQL
Sbjct 6035 TYSRLISLMGFKLDLTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHATRDSIGTNFPLQL 6094
Query 6035 GFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQM 6094
GFSTG++ V TG + F + +A+ PPG+QFKHL+PLM +G W+VVRI+IVQM
Sbjct 6095 GFSTGIDFVVEATGMFAERDGYVFKKAAARAPPGEQFKHLVPLMSRGQKWDVVRIRIVQM 6154
Query 6095 LSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHH 6154
LSD L +L+D VV V WA FELT ++YF K+G E C +C++RATCF++ + Y CW H
Sbjct 6155 LSDHLVDLADSVVLVTWAASFELTCLRYFAKVGKEVVCSVCNKRATCFNSRTGYYGCWRH 6214
Query 6155 SIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKR 6214
S DY+YNP ++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+CF K
Sbjct 6215 SYSCDYLYNPLIVDIQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRCLAVHDCFCKS 6274
Query 6215 VDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWK 6274
V+W +EYPII +E+ +N +CR +Q ++ +AA+L +++ V +DIGNPK + CV D +K
Sbjct 6275 VNWNLEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKGYD--FK 6332
Query 6275 FYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNL 6334
FYDA P +++ Y Y H D+F DG+C+FWNCNVD+YPAN++VCRFDTRVLS L
Sbjct 6333 FYDASPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLSKL 6389
Query 6335 NLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLK 6394
NLPGC+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD+PC +DYVPL+
Sbjct 6390 NLPGCNGGSLYVNKHAFHTNPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLR 6449
Query 6395 SATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSL 6454
SATCITRCNLGGAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFTRLQSL
Sbjct 6450 SATCITRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQSL 6509
Query 6455 ENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRN 6514
ENV +N+VN GHFDG+ GE+P ++I V K+ DV +F+N T P NVA EL+A+R+
Sbjct 6510 ENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAERS 6569
Query 6515 IKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVF 6574
I+P PE+K+ + + + N V+WDY +D+ ST VC TD+ L V
Sbjct 6570 IRPHPELKLFRSSNIHVCWNHVLWDYAKDSVFCSSTYKVCKYTDL------QCIESLNVL 6623
Query 6575 FDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEA-VKTQFNYY 6631
FDGR +G ++ F+ RNGV I +K L GP++A LNGV + +G++ V+ F
Sbjct 6624 FDGRDNGALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFAMR 6683
Query 6632 KKVDGVV-----------QQLPE--------------------TYFTQSRNLQEFKPRSQ 6660
+ D V+ + P+ T FTQSR L F PRS+
Sbjct 6684 RDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRFLSSFSPRSE 6743
Query 6661 MEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDF 6720
ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHLLIGLA+R K+S +++F
Sbjct 6744 MEKDFMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRPKKSNLVIQEF 6803
Query 6721 IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEIS 6780
+P DS++ +YFITD +GSS+ VC+VIDLLLDDFV+I+KS +L VSKVV V +D+ +
Sbjct 6804 VPYDSSIHSYFITDENSGSSESVCTVIDLLLDDFVDIVKSLNLKCVSKVVNVNVDFKDFQ 6863
Query 6781 FMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMM 6840
FMLWC + V TFYP+LQ++ W+PG MP LYK +E+ +L NYG TLP G MM
Sbjct 6864 FMLWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPMERVNLWNYGKPITLPTGCMM 6923
Query 6841 NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND 6900
NVAKYTQLCQYL+T TLAVP NMRV+H GAGSDKGVAPG+AVLRQWLP+G++LVD+D+N
Sbjct 6924 NVAKYTQLCQYLSTTTLAVPANMRVLHLGAGSDKGVAPGSAVLRQWLPSGSILVDNDMNP 6983
Query 6901 FVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLA 6960
FVSD+ ++ G+C T+ +WDLIISDMYDP TKN+ + N SK+GFFTY+C I+ KLA
Sbjct 6984 FVSDSVASYYGNCITLPFDCQWDLIISDMYDPLTKNIGEYNVSKDGFFTYLCHLIRDKLA 7043
Query 6961 LGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGY 7020
LGGSVAIKITE SWNA+LY LMG FA+WT F TNVNASSSE FLIG N+L + R +IDG
Sbjct 7044 LGGSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWLNRTRNEIDGK 7103
Query 7021 VMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLII 7080
MHANY+FWRN+ +YSLFDM+KFPLK GTAV+SLK QIND++LSL+ KG+L++
Sbjct 7104 TMHANYLFWRNSTMWNGGAYSLFDMTKFPLKAAGTAVVSLKPDQINDLVLSLIEKGKLLV 7163
Query 7081 RENNRVVISSDVLVN 7095
R+ + V D LVN
Sbjct 7164 RDTRKEVFVGDSLVN 7178
Score = 88.6 bits (218), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 236/1025 (23%), Positives = 393/1025 (38%), Gaps = 219/1025 (21%)
Query 2 ESLVPGFNEKTHVQLS---LPVLQ-------VRDVLVRGFGDSVEEVLSEARQHLKDGTC 51
E V G HV++ LP L+ +RD+ V + ++V + L+ G+
Sbjct 46 EPKVKGKTLVNHVRVDCSRLPALECCVQSAIIRDIFV---DEDPQKVEASTMMALQFGSA 102
Query 52 GLVEVEK----------GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQY 97
LV+ K GVLP+ +F + T HV +L + +G+
Sbjct 103 VLVKPSKRLSVQAWAKLGVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCL 162
Query 98 GRSGETLGVLVPHVGEIPVAYRK------VLLRKNGNKGA---GGHSYGADLKSFDLGDE 148
G +G +G VP V IP ++ +LLRK GNKG+ G + +D E
Sbjct 163 G-NGRFIGWFVP-VTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE 220
Query 149 LGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARA 208
D E+ N K+S L+R G +VD C G C+ L
Sbjct 221 ---DACEEVHLNPRGKYSCK-AYALLRGYRGVKPILFVDQYGCDYTG----CLAKGLEDY 272
Query 209 GKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKS-YELQTPFEIKLAKKF---- 263
G TLSE + R ++E +AW+ +R ++ LQT ++ +
Sbjct 273 GDL--TLSEMKELSPVWRDSL---DNEVVVAWHVDRDPRAVMRLQTLATVRSIEYVGQPI 327
Query 264 -DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLS 318
D +G+ P + N+I+K + PR+ + L + + + C
Sbjct 328 EDMVDGDVVMREPAHLLAPNAIVKRL-PRLVETML-------------YTDSSVTEFCYK 373
Query 319 TLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPAC----- 373
T + CD CG + Q G +V + CG G++P N + CP C
Sbjct 374 TKL-CD-CGFIT-QFG-YVDCCGDTCGFR----------GWVPGNMMDGFPCPGCCKSYM 419
Query 374 ------HNSEVGPEHSL--AEYHNESGLKTILRKGGRTIAFGGCVF--SYVGCHNKCAYW 423
+S V PE + + + ++ G + FGG + Y G W
Sbjct 420 PWELEAQSSGVIPEGGVLFTQSTDTVNRESFKLYGHAVVPFGGAAYWSPYPG------MW 473
Query 424 VPRASANIGC----NHTGVVG-EGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILA 478
+P +++ +TGVVG + D + L + V + G+ E+ AI+
Sbjct 474 LPVIWSSVKSYSYLTYTGVVGCKAIVQETDAICRFLYMDYVQ-HKCGNL---EQRAIL-- 527
Query 479 SFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFAS 538
GLD +Q++ + G++ + +L + F
Sbjct 528 --------------GLDDVYHRQLLVNRGDYSL-----------------LLENVDLFVK 556
Query 539 EAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA-MMFTSDLATNNLVV 597
R+ F+ T + + L +LDG+ S LI + FTS + + V
Sbjct 557 R-----RAEFACKFATCGDGLVPL------LLDGLVPRSYYLIKSGQAFTSLMVNFSREV 605
Query 598 ------MAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRD------G 645
MA + V++ ++++ + G V + K + + K E + D G
Sbjct 606 VDMCMDMALLFMHDVKVATKYVKKVTGKVAVRFKALGIAVVRKITEWFDLAVDTAASAAG 665
Query 646 WEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNL 705
W + ++ V ++T +E+ E V+ F F + DS+ + ++
Sbjct 666 WLCYQLVN--GLFAVANGVITFIQEVPELVKNFVDKFKTFFKVLIDSMSV------SILS 717
Query 706 GETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVL---TEEVVLKTGD 762
G T V + R C+ A ++ + ++LP ++ E G+
Sbjct 718 GLTVVKTASN--RVCL-------------AGSKVYEVVQKSLPAYIMPVGCSEATCLVGE 762
Query 763 LQP--LEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEK-YCALAPN----MMVTNNTFTL 815
++P E + V+APL C +I +K Y A + ++V N+T +
Sbjct 763 IEPAVFEDDVVDVVKAPLTYQGCCKPPSSFEKICIVDKLYMAKCGDQFYPVVVDNDTVGV 822
Query 816 KGG------APTKVTFGDD-TVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEV 868
A KV F D V EV + + I F LD D VL++ CS + V+ +
Sbjct 823 LDQCWRFPCAGKKVVFNDKPKVKEVPSTRKIKIIFALDATFDSVLSKACSEFEVDKDVTL 882
Query 869 NEFACVVADAVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFY 925
+E VV DAV TL P E + T + L+ YLFDE GE +AS MYCSF
Sbjct 883 DELLDVVLDAVESTLSPCKEHGVIGTKVCALLERLVDDYVYLFDEGGEEVIASRMYCSFS 942
Query 926 PPDED 930
PDED
Sbjct 943 APDED 947
Score = 59.3 bits (142), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 52/153 (34%), Positives = 82/153 (54%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV D+++ ++V V+VN AN + HG GVAGA+ KA A E+ D +
Sbjct 1319 ITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKAFINETADMVKA 1378
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNV--NKGEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G +VGG +G L K L++VGP+ + E LL+ AY++ N+ + ++ L+SA
Sbjct 1379 QGVCQVGGCYESTGGKLCKKVLNIVGPDARGHGNECYSLLERAYQHINKCDNVVTTLISA 1438
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + V NV L +++ +D
Sbjct 1439 GIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFD 1471
Score = 40.0 bits (92), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 52/213 (24%), Positives = 84/213 (39%), Gaps = 25/213 (12%)
Query 1596 PTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLR-VEAFEYYHTTDPSFLGRYMSALNHTK 1654
P ++ D+ K++ E +T P D T V AF+ ++ S S H K
Sbjct 1047 PDQVEAFDIEKVEDSILSELQTELNAPADKTYEDVLAFDAIYSETLSAFYAVPSDETHFK 1106
Query 1655 KWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALI 1714
V G S NC+L + L+ +Q + L+F +Q + +AG F +
Sbjct 1107 ------VCGFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKL 1160
Query 1715 LAYCNKT-VGELGDVRETMSYLFQHANLDSC--KRVLNVVCKTCGQQQTTLKGVEAVMYM 1771
+ K+ + G +Y F L C K N C CG + L+G++AV +
Sbjct 1161 VKSAPKSIILPQGGYVADFAYFF----LSQCSFKVHANWRCLKCG-MELKLQGLDAVFFY 1215
Query 1772 GTLSYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
G + V C CG T L+ + P+
Sbjct 1216 GDV--------VSHMCKCGNSMT--LLSADIPY 1238
>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059
Score = 5261 bits (13647), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2699/5564 (49%), Positives = 3632/5564 (65%), Gaps = 200/5564 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + + D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTV--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLK-PVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
D K P +++ ++K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAKEPKEINIIKLSGVKKPF--------KVEDSVIVNDDTSEIKYVKSLSIVDVYDMWL 2079
Query 2101 DNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNI 2156
++ N LSR + + T+ G+ V S+P D + KP N VV N
Sbjct 2080 TGCRCVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNK 2137
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
++ C N ++ + F LL + K T +A + + +F
Sbjct 2138 ISACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFL 2188
Query 2217 YLKSPNFSKLINII--IWFLLLSVCLGSLIYST---AALGVLMSNLG-----------MP 2260
K ++ II I+ L + ++I+S +G L + +G +
Sbjct 2189 TFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIVQWIKNTFSLV 2248
Query 2261 SYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTA 2320
+ C Y + N YC GSI C CL+G D LD Y +++ +Q ++ D A
Sbjct 2249 TICDLYSIQDVGFKN----QYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRA 2299
Query 2321 F-------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINL 2371
F +V E ++Y L+T +FY L +Q+ ++ + ++ W + L+++L
Sbjct 2300 FVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELLMLSTLHWSVRLLVSL 2359
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
M P +R YI ASF ++ + HV GC+ S C+ CYKRNR+ RV+C+TIV G+
Sbjct 2360 ANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMI 2419
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2420 RYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTV 2479
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEE 2551
V + L++D+ GQ+TY+ + S FV+ NL + K ++V+V + + ++
Sbjct 2480 TDVKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DK 2537
Query 2552 SSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKT 2611
++ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L
Sbjct 2538 ANFLNAAVFYAQSLFRPILMVDKILITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNA 2597
Query 2612 LVATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSC 2670
L+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SC
Sbjct 2598 LIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESC 2657
Query 2671 NNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIR 2730
NN + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2658 NNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLK 2717
Query 2731 SAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLI 2790
A K L +LT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2718 KACCKTGLKLELTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLV-CFIG--LWCL 2774
Query 2791 TPVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTN 2847
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2775 MPTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2848 DKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTD 2907
ACP++ AV+ ++ G V +P +LR LHF+ SA G CYTP I Y++
Sbjct 2834 SMACPIVVAVVDQDFGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2908 FATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPN 2966
F S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+ P
Sbjct 2893 FYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRLPE 2952
Query 2967 TYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNL 3026
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L
Sbjct 2953 VLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3027 LTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL 3086
+ +F L QP+ L ++AS +AG I+A++V YY ++ +RAFG+Y+ +V N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLGFYYLIKLKRAFGDYTSIVFVNVIVWC 3072
Query 3087 MSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYII 3146
++F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIS 3132
Query 3147 CISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ + H +W FS R++ + S TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVFS--YCRQLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSG 3265
YL+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3266 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKS 3325
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3326 NHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSP 3385
+ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3386 SGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFY 3445
G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3446 GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3505
GP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQV 3488
Query 3506 TQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSG 3565
D V + L++ TG+++ + A++K L +NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3566 VTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFA 3625
+ QS R +KG W++ + ++ +W++F ++ N L + + + A
Sbjct 3546 IKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLA 3604
Query 3626 MMFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
M+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+
Sbjct 3605 MLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3685 YASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSN 3743
Y +++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+
Sbjct 3664 YGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGT 3721
Query 3744 YSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
Y+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N
Sbjct 3722 YTWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSL 3780
Query 3804 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMS 3863
FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++
Sbjct 3781 FRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLT 3840
Query 3864 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3923
DVKC + LL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL +
Sbjct 3841 DVKCANGGLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPA 3900
Query 3924 AVD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVV 3976
AVD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + +
Sbjct 3901 AVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQ 3960
Query 3977 LKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTM 4036
LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M
Sbjct 3961 LKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSM 4020
Query 4037 LRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALW 4096
+RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W
Sbjct 4021 VRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVW 4080
Query 4097 EIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSC 4154
+IQ + D+D QL EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4081 QIQTIQDSDGTNKQLHEISDDCN----WPLVIIANRHNEVSATVLQNNELMPAKLKTQVV 4136
Query 4155 AAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCR 4214
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+
Sbjct 4137 NSGPDQTCNTPTQC--YYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCK 4193
Query 4215 FVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAV 4274
F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+V
Sbjct 4194 FTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSV 4253
Query 4275 DAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHI 4334
D K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR +
Sbjct 4254 DPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCRARV 4313
Query 4335 DHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA 4394
+HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS
Sbjct 4314 EHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSK 4371
Query 4395 DAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDE 4453
D +FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRFQ DE
Sbjct 4372 DT-NFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRFQRVDE 4430
Query 4454 DDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTK 4513
+ + +D +FVVKR + Y E Y +KDC VA+HDFF F ++G VPHI R+ LTK
Sbjct 4431 NGDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKDLTK 4490
Query 4514 YTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGER 4573
YTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY LG
Sbjct 4491 YTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKLGPI 4550
Query 4574 VRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLL 4633
+AL+ +F D + G+VG+LTLDNQDLNG WYDFGD++ PG GV + DSYYS +
Sbjct 4551 FNRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYYSYM 4610
Query 4634 MPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNC 4693
MP+LT+ AL E +V+ Y +DL++YDFT+ +L+LF++YFK+W YHPN V+C
Sbjct 4611 MPMLTMCHALDCELYVNN----AYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNTVDC 4666
Query 4694 LDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNL 4753
DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N DV+
Sbjct 4667 QDDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMDVDT 4726
Query 4754 HSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYD 4813
H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+DFYD
Sbjct 4727 HRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYD 4786
Query 4814 FAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFD 4873
F +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+
Sbjct 4787 FILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFE 4846
Query 4874 CYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQ 4933
YDGGCI A QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQ
Sbjct 4847 IYDGGCIPAAQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQ 4906
Query 4934 MNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNM 4993
MNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +M
Sbjct 4907 MNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDM 4966
Query 4994 LKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQ 5053
L+ + DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS S RFYRLANECAQ
Sbjct 4967 LRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLANECAQ 5026
Query 5054 VLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVR 5113
VLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D +R
Sbjct 5027 VLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDLSIR 5086
Query 5114 NLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKN 5173
LQ RLY +YR+ VD+ FV E+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I
Sbjct 5087 ALQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIANISA 5146
Query 5174 FKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAG 5233
F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYP PSRILGAG
Sbjct 5147 FQQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPVPSRILGAG 5206
Query 5234 CFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLD 5293
CFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL++EL +LD
Sbjct 5207 CFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNELGNQILD 5266
Query 5294 MYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKC 5353
YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC
Sbjct 5267 SYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKC 5326
Query 5354 CYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQV 5413
CYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L NG V
Sbjct 5327 CYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMV 5386
Query 5414 FGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSY 5473
FGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK SY
Sbjct 5387 FGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFKQSY 5446
Query 5474 GIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAV 5533
AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K + + V
Sbjct 5447 ASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELTNGV 5506
Query 5534 VYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVA 5591
YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F +NV
Sbjct 5507 YYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQNNVV 5563
Query 5592 NYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPI 5651
NYQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I
Sbjct 5564 NYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLNI 5623
Query 5652 DKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVV 5711
+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+
Sbjct 5624 NDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYELSVI 5683
Query 5712 NARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAE 5771
NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RCP E
Sbjct 5684 NARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRCPKE 5743
Query 5772 IVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWR 5831
IVDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL NP W
Sbjct 5744 IVDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANPLWH 5803
Query 5832 KAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITR 5891
KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITR
Sbjct 5804 KAVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITR 5863
Query 5892 AKVGILCIMSDRDLYDKLQFTSLEIPRRNVAT-LQAENVTGLFKDCSKVITGLHPTQAPT 5950
AK GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP AP+
Sbjct 5864 AKKGILCVMSNMQLFEALQFTTLTVDKVPQAVETRVQCSTNLFKDCSKSYSGYHPAHAPS 5923
Query 5951 HLSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVR 6009
L+VD K+K G GI +TY RLIS+MGFK++ ++GY +FIT+EEA++ VR
Sbjct 5924 FLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEAVKRVR 5983
Query 6010 AWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGD 6069
AW+GFD EG HATR+++GTN PLQLGFSTG++ V TG + F + AK PPG+
Sbjct 5984 AWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAKAPPGE 6043
Query 6070 QFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPE 6129
QFKHLIPLM +G W+VVR +IVQM +D L +LSD VV V WA FELT ++YF K+G E
Sbjct 6044 QFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFAKVGRE 6103
Query 6130 RTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVH 6189
+C + +RAT +++ + Y CW HS+ DY+YNP ++D+QQWG+ G+L SNHDLYC VH
Sbjct 6104 ISCNVSTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDLYCSVH 6163
Query 6190 GNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLAD 6249
AHVAS DAIMTRCLAV++CF ++W +EYPII +EL IN +CR +Q +++KAA+L +
Sbjct 6164 KGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKAAMLCN 6223
Query 6250 KFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLF 6309
++ + +DIGNPKAI CV D ++KFYDAQP ++ L Y + H D F DG+C+F
Sbjct 6224 RYTLCYDIGNPKAIACVK--DFDFKFYDAQPI---VKSVKTLLYFFEAHKDSFKDGLCMF 6278
Query 6310 WNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPF 6369
WNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +LK +PF
Sbjct 6279 WNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHLKPMPF 6338
Query 6370 FYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISA 6429
FYYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR YL++YN +A
Sbjct 6339 FYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYNTATTA 6398
Query 6430 GFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDG 6489
GF+ WVYK FD YNLWNTFT+LQSLENV +N+V GH+ GQ GE+P +IIN+ V K+D
Sbjct 6399 GFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDK 6458
Query 6490 VDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHIS 6549
DV +F N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY R++ +
Sbjct 6459 EDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSN 6518
Query 6550 TIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGP 6609
T GVC TD+ + L V FDGR +G ++ F+ + NGV I+ VK L GP
Sbjct 6519 TYGVCMYTDLK------LIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGP 6572
Query 6610 KQASLNGVTL--IGE-------AVKTQ-----FNYYKKVDGVVQQLPE------------ 6643
+A LNGV + +G+ AV+ + F+ + + Q P+
Sbjct 6573 PRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVG 6632
Query 6644 --------TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHS 6695
T FTQSR + F R+ ME DF+ L D FI++Y LE YAFEHIVYG+F+
Sbjct 6633 GNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQK 6692
Query 6696 QLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFV 6755
+GGLHLLIGL +R + S +++F+ DS++ +YFITD ++G SK VC+VID+LLDDFV
Sbjct 6693 IIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFV 6752
Query 6756 EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKM 6815
++KS +L+ VSKVV V +D+ + FMLWC D V TFYP+LQ++ W+PG +MP LYK
Sbjct 6753 ALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSMPVLYKY 6812
Query 6816 QRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKG 6875
+E+ L NYG TLP G MMNVAKYTQLCQYLNT TLAVP N RV+H GAGS+KG
Sbjct 6813 LNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNTRVLHLGAGSEKG 6872
Query 6876 VAPGTAV----------LRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLI 6925
VAPG+AV LRQWLP GT+LV +DL FVSD+ +T GDC T+ +WDLI
Sbjct 6873 VAPGSAVLRQWLPAGTILRQWLPAGTILVHNDLYPFVSDSVATYFGDCITLPFDCQWDLI 6932
Query 6926 ISDMYDPKTKNVTKENDSKEGFFTYI-CGFIQQKLALGGSVAIKITEHSWNADLYKLMGH 6984
ISDMYD + + +YI C I+ KLALGGSVAIKITE SWNA+LYKLMG+
Sbjct 6933 ISDMYD-----LLLDIGVHVVRCSYIHCHMIRDKLALGGSVAIKITEFSWNAELYKLMGY 6987
Query 6985 FAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIF 7028
FA+WT F TN NASSSE FLIG NYLGKP+ +IDG VMHA F
Sbjct 6988 FAFWTVFCTNANASSSEGFLIGINYLGKPKVEIDGNVMHAIICF 7031
Score = 84.0 bits (206), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T + V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFD 1425
Score = 70.1 bits (170), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 227/1007 (23%), Positives = 370/1007 (37%), Gaps = 179/1007 (18%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIAP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYIKDYKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYAGKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E SV L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSVDSL-GAAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F G I ++ S A G
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYF---GKNIPRYASAVAQAFRSG---- 710
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK +S++ F + I + G+K+ + G + HS L +
Sbjct 711 -AKVGLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP K ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKTKQKGIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRCVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGEFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTED---DY 955
+ + +LFDE+GE LA +YC+F P++D D EE E D
Sbjct 936 KLEDNSLFLFDEAGEEVLAPKLYCAFTAPEDD----DFLEESGVEEDDVEGEETDLTVTS 991
Query 956 QGKPLEFGATSAALQPEEEQE--EDWLDDDSQQTVGQQDGSEDNQTT 1000
G+P A + EE E ED LDD ED Q +
Sbjct 992 AGEP------CVASEQEESSEILEDTLDDGPCVETSDSQVEEDVQMS 1032
>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793
Score = 4347 bits (11274), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2315/4968 (47%), Positives = 3160/4968 (64%), Gaps = 202/4968 (4%)
Query 2171 YFFTLLLQLCTFTRSTNSRIKASMPT---TIAKNTVK---SVGKFCLEASFNYLKSPNFS 2224
Y F+LL + + ++ A +P I K +VK KF F Y+K
Sbjct 1984 YLFSLLAICFRALKKRDMKVMAGVPERTGIILKRSVKYNYKALKFFFRLKFQYIKV---- 2039
Query 2225 KLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTG 2284
FL S+ L +L Y+ + + + +G P C Y +GY NST YC G
Sbjct 2040 --------FLKFSLVLYTL-YALMFMFIRFTPVGTP-ICKRYTDGYANST-FDKNDYC-G 2087
Query 2285 SIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLA 2344
++ C +CL G + L + I K L L + + I+F FF +G+
Sbjct 2088 NVLCKICLYGYEELSDFTHTRVIW---QHLKDPLIGNILPLFYLVFLIIFGGFFVRIGIT 2144
Query 2345 AIMQLFFSY--FAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVD 2402
+ + + A+ + N WL+ L+ P ++M + + + HV+
Sbjct 2145 YFIMQYINAAGVALGYQDNVWLLHLL-------PFNSMGNIIVVAFIVTRILLFLKHVLF 2197
Query 2403 GCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGS 2462
GC+ +C+ C K + TRV TI+ GV +SFYV ANGGK FCK HN+ CV+CD++ G
Sbjct 2198 GCDKPSCIACSKSAKLTRVPLQTILQGVTKSFYVNANGGKKFCKKHNFFCVDCDSYGYGC 2257
Query 2463 TFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFV 2522
TFI+D +A +LS K + PT ++ I+D V NG +LY K + + +
Sbjct 2258 TFINDVIAPELSNVTKLNVIPTGPATIIIDKVEFSNGFYYLYSGSTFWKYNFDITEAKYA 2317
Query 2523 NLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGD 2582
D L+ N + + +VF+ S + K+A VY+SQL+C+PI L+D AL++ +
Sbjct 2318 CKDVLKNCN----ILTDFVVFN-NSGSNVTQVKNACVYFSQLLCKPIKLVDSALLASL-- 2370
Query 2583 SAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFV 2642
+ + + + A+V S++F + + + R+
Sbjct 2371 NVDFSANLHKAFVEVLSNSFGKDLSNCSNM----------------------NECRESLG 2408
Query 2643 DSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVE-NMTPRDLGACIDCSARHINA 2701
SDV ++ + +H+ D+ ++ S NN +++Y K E + D+ C+ A+ +N
Sbjct 2409 LSDVPEEEFSAAVSEAHRYDVLISDVSFNNLIVSYAKPEEKLAVHDIANCMRVGAKVVNH 2468
Query 2702 QVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALK 2761
V N+ ++W KDF++LSE+ RK I K + F LT R + + T +A K
Sbjct 2469 NVLTKDNVPVVWLAKDFIALSEEARKYIVRTTKTKGINFMLTFNDRRMHLTIPTISVANK 2528
Query 2762 GGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIG-----YKAIDGGV 2816
G + + +L + F + LI + V + DFS+++ +K I+ GV
Sbjct 2529 KGAGLPSLFTRL------YSFFWHLCVLIVVLFVATSLLDFSAQVTSDTQYDFKYIENGV 2582
Query 2817 TRDIASTDTCFANKHADFDTWFSQRGGSY-TNDKACPLIAAVITREVGFVVPGLPGTILR 2875
+ C N +F+ W + + GS TN + CP++ + EV ++ PG+P +
Sbjct 2583 LKVFEKPLDCVHNAFVNFNEWHNAKFGSIPTNSRRCPIVVGT-SDEVRYI-PGVPAGVF- 2639
Query 2876 TTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYD 2935
G L F +C+ L + +C+ + CT G+ V YCY
Sbjct 2640 -LYGKSLIFAMSTIFGTSGLCFDDRGLTD-----PDSCIFNSACTTLSGIGGRNV-YCYR 2692
Query 2936 TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCERSEA 2994
V++ + Y SL P + Y LMDG+ I P G +R + T YCR G C S+A
Sbjct 2693 EGVVDNAKLYSSLLPHSYYRLMDGNHIVLPEIITRGFGIRTIKTQAMTYCRTGECIDSQA 2752
Query 2995 GVCVSTSGRWVLNNDYYRSLPG--VFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGI 3052
GVCV +V Y PG CG +LL N+ I +S I+ +
Sbjct 2753 GVCVGLDRFFV-----YSKTPGSDYVCGTGFFSLLFNVIGMFSNSIPVTVMSGQILLNCV 2807
Query 3053 VAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYL 3112
VA + F +F+R FG+ S F L + V L+ V + + + Y L
Sbjct 2808 VAFTAVMACFAFTKFKRLFGDMS----FGVLSVGLCTVVNNLSYVVT-QNSIGMLAYATL 2862
Query 3113 TFYLTNDV--SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VF 3167
F T V S++ H+ + + + L P+W+ +AY+IC + F N K +V +F
Sbjct 2863 YFLCTKGVRYSWVWHVGFAISYCFLAPWWVVLAYLICALLE----FLPNLFKLKVSTQLF 2918
Query 3168 NGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSY 3226
G F +FE AA TF+L+ Y KL + + + +Y A YN+YKY+SG+ Y
Sbjct 2919 EGDKFVGSFESAASGTFVLDMHSYQKLANSI--STEKLKQYCASYNRYKYYSGSASEADY 2976
Query 3227 REAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCG 3286
R A HLAKA++DF+N D LY PP S S LQ+G RKMA PSG VEGC+V+V+ G
Sbjct 2977 RLACFAHLAKAMSDFANDHMDKLYTPPTVSYNST-LQAGLRKMAQPSGIVEGCIVRVSYG 3035
Query 3287 TTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSM 3345
TLNGLWL D V CPRHVI + + ++++ ++ L+R HNF + +GN+ L VI SM
Sbjct 3036 NLTLNGLWLGDTVICPRHVIASNTTNVIDYDHAMSLVRL--HNFSISSGNMFLGVISASM 3093
Query 3346 QNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLN 3405
+ +L +KV+ +N TP Y + ++PG +F++LACY+GS +GVY MR N+TI+GSF++
Sbjct 3094 RGTLLHIKVNQSNVNTPNYTYKVLKPGDSFNILACYDGSAAGVYGVNMRTNYTIRGSFIS 3153
Query 3406 GSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITV 3465
G+CGS G+NI+ V FCYMHH+EL +G H G+D++G YG + D+ T Q G +T
Sbjct 3154 GACGSPGYNINNGVVEFCYMHHLELGSGCHVGSDMDGTMYGKYEDQPTLQIEGASNLVTE 3213
Query 3466 NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVL 3525
NV +WLY A+INGDRW+L+ + ++ +N A++ L +VD L A+TG+ V
Sbjct 3214 NVCSWLYGALINGDRWWLSSVSVGVDTYNEWALRNGMTALK--NVDCFSLLVAKTGVDVG 3271
Query 3526 DMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSA-VKRTIKGTHHWLL 3584
+ AS+++L N G++ILG L DEFT +VV+Q GVT QS V R +
Sbjct 3272 RLLASIQKLHGN-FGGKSILGCTSLCDEFTLSEVVKQMYGVTLQSGKVSRAFRNA----- 3325
Query 3585 LTILTSLLVLVQSTQW--SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLP 3642
+I+ LL L S S F++ P + II S+ M+ VKHK FL L+LLP
Sbjct 3326 -SIVCCLLFLFLSEMLNHSKLFWINPGYITPVFLAIIVASSALMLLVKHKLLFLQLYLLP 3384
Query 3643 SLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYD 3702
SL V+ +N ++ + ++ D GF + + + ++ L T R +
Sbjct 3385 SLCIVSGYN-IFKDYHFYTYMLEEFDY-KVPFGGFNVTGVLNISLCCFVMGLHTFR--FL 3440
Query 3703 DGARRVWT-LMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFM 3761
++++ ++ VLT++Y YY + + LI++ S + T F+ +
Sbjct 3441 QTPNKIFSYVVAVLTVLYTYYY------STDVLGLILTSMSGF----TNYWFIGTATYKL 3490
Query 3762 CVEYCP--IFFITGNTLQCIMLVYCFLGYFCTC-YFGLFCLLNRYFRLTLGVYDYLVSTQ 3818
P + + ++ ++ +Y LGY C C Y+G +NR+ +LTLG Y++ VS
Sbjct 3491 ATYVLPHTSLLDSFDAIKAVVFLYLLLGY-CNCVYYGSLYWINRFCKLTLGCYEFKVSAA 3549
Query 3819 EFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQ 3878
EF+YM + GL P DA L++KL+GVGG+ IK+++VQSK++D+KCT+VVLL L
Sbjct 3550 EFKYMVANGLRAPTGVFDALILSLKLIGVGGRKTIKISSVQSKLTDLKCTNVVLLGCLSN 3609
Query 3879 LRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNR 3938
+ + ++S+ WA CV LHN I L D A E +++LL+ LS A +++L + ++
Sbjct 3610 MNIAANSREWAYCVDLHNKINLCNDAEAAQEMLLALLAFFLSKNSAFGVDELLDSYFNDS 3669
Query 3939 ATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQ 3998
+ LQ++A+ + +LPSY A+ TA+++YE A+ANG ++K+L+ ++NVAKSEFDR+A+ Q
Sbjct 3670 SVLQSVAATYVNLPSYLAYETARQSYEDALANGSPPQLVKQLRHAMNVAKSEFDREASTQ 3729
Query 3999 RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP 4058
RKL++MA+QA +QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I++ A+DG VP
Sbjct 3730 RKLDRMAEQAASQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLAKDGVVP 3789
Query 4059 LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDN 4118
L+IIP +A KL +V+ D +Y YA +W + + D D K V E+ N
Sbjct 3790 LSIIPAVSATKLNIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAKEVVTSN 3849
Query 4119 SPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGG 4178
+LAWPL + R +KLQNNE+ P ++Q A + D NAL Y+ G
Sbjct 3850 VESLAWPLFLNCERI---IKLQNNEIIPSKIKQRPIKA-EGEGVVADGNAL--YSNEGGR 3903
Query 4179 RFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLN 4238
F+ A +SD DLK ++ G+ I ELEPPC+F+ + P GP VKYLYF++ LNNL
Sbjct 3904 TFMYAFISDKPDLKVVKWEFDGGSNAI--ELEPPCKFLVEAPSGPVVKYLYFVRNLNNLR 3961
Query 4239 RGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKML 4298
RG VLG + ATVRLQAG TE NS++L+ CAFAVD K Y D + SG +P+ NCVKML
Sbjct 3962 RGAVLGFIGATVRLQAGKQTEQATNSSLLTLCAFAVDPPKTYLDAVKSGHRPVGNCVKML 4021
Query 4299 CTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCAN 4358
+G GQAIT EA+ +Q+S+GGAS CLYCR H++HP+ GFC L+GKYVQ+P
Sbjct 4022 ANGSGNGQAITNGVEASTNQDSYGGASVCLYCRAHVEHPDMDGFCKLRGKYVQVPLGTL- 4080
Query 4359 DPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGT 4418
DP+ F L+NTVC VCG W+ GC+CD+ ++QS D+ +LNRV G SAARL P G+
Sbjct 4081 DPIRFVLENTVCKVCGCWQANGCTCDR---AVIQSVDS-GYLNRVRGSSAARLEPL-NGS 4135
Query 4419 STDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETI 4478
T V+RAFD+YN VA +KFLK NC R + D+ D ++++VK+ T S +HE++I
Sbjct 4136 DTHHVFRAFDVYNRDVACISKFLKVNCVRLKNLDKHD----AFWIVKKCTKSVMEHEQSI 4191
Query 4479 YNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEIL 4538
YNL+ DC AVAKHDFF ++ + ++ RQ LT+YTM DL YALR+FDE NC+TLK+IL
Sbjct 4192 YNLISDCGAVAKHDFFTWKEGRSVYGNVCRQDLTEYTMMDLCYALRNFDENNCETLKKIL 4251
Query 4539 VTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLT 4598
V CD+ YF+ K W+D VEN D+ RVYA LG V +A+LK V++CDAM GIVGV+T
Sbjct 4252 VVVGACDESYFDNKLWFDPVENEDVHRVYAKLGTIVARAMLKCVKYCDAMVEQGIVGVIT 4311
Query 4599 LDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDL-TKPY 4657
LDNQDLNG++YDFGDF+ + G GVP+ SYYS +MP++ +T L +E + +D+ + +
Sbjct 4312 LDNQDLNGDFYDFGDFVTSVKGMGVPICTSYYSYMMPVMGMTNCLASECFIKSDIFGEDF 4371
Query 4658 IKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTS 4717
+DLL YDFTE ++ LF++YFK+W QTYHPNC +C D+ CI+HCANFN LF+T P T+
Sbjct 4372 RTFDLLAYDFTEHKVNLFNKYFKHWGQTYHPNCEDCHDESCIVHCANFNTLFATTIPITA 4431
Query 4718 FGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASG 4777
FGPL RK ++DGVP V + GYHF++LG+V N+D+NLHSSRL+ ELL + ADP++ AS
Sbjct 4432 FGPLCRKCWIDGVPLVTTAGYHFKQLGIVWNKDLNLHSSRLTINELLQFCADPSLLIASS 4491
Query 4778 NLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQD 4837
L+DKRT CFSVAAL + QTVKPG+FN++FYDF S+GFF+EGS + LKHFFFAQ
Sbjct 4492 PALVDKRTVCFSVAALGTGMTNQTVKPGHFNREFYDFLRSQGFFEEGSELTLKHFFFAQK 4551
Query 4838 GNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFP 4897
G+AA+ D+DYYRYN T+ DI Q V ++V YF Y+GGCI A +VIVNNL+KSAG+P
Sbjct 4552 GDAAVRDFDYYRYNRTTVLDICQARVVYQIVQCYFGMYEGGCITAKEVIVNNLNKSAGYP 4611
Query 4898 FNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICST 4957
FNK+GKA LYYDS+SYE+QD L+AYTKRN+IPT+TQ+NLKYAIS K+RARTV GVS+ ST
Sbjct 4612 FNKFGKAGLYYDSLSYEEQDDLYAYTKRNIIPTMTQLNLKYAISGKDRARTVGGVSLLST 4671
Query 4958 MTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRA 5017
MT RQ+HQK LKSI TRGA+VVIGT+KFYGGW NMLKT+ DVENPHLMGWDYPKCDRA
Sbjct 4672 MTTRQYHQKHLKSIVNTRGASVVIGTTKFYGGWDNMLKTLIKDVENPHLMGWDYPKCDRA 4731
Query 5018 MPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDA 5077
+PNM+R++++++L KH CCS S R+YRL NE AQVL+EMV G YVKPGGT+SGDA
Sbjct 4732 LPNMIRMISAMILGSKHVNCCSSSDRYYRLCNELAQVLTEMVYSNGGFYVKPGGTTSGDA 4791
Query 5078 TTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEF 5137
TTAYANSVFNI QA +ANVN LLS D N + V+ LQ +LY+C YR+ VD FV E+
Sbjct 4792 TTAYANSVFNIFQATSANVNRLLSVDSNTCNNIEVKQLQRKLYDCCYRSSSVDQSFVEEY 4851
Query 5138 YAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDL 5197
+ YLRKHFSMMILSDD VVC+NS YA+ G VA + FK+VLYYQNNVFMS +KCW E D+
Sbjct 4852 FGYLRKHFSMMILSDDGVVCYNSEYAALGYVADLNAFKAVLYYQNNVFMSASKCWIEPDI 4911
Query 5198 TKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAID 5257
KGPHEFCSQHTM + D YLPYPDPSRIL AG FVDDIVKTD +++ER+VSLAID
Sbjct 4912 NKGPHEFCSQHTMQIVDKDGTYYLPYPDPSRILSAGVFVDDIVKTDPVILLERYVSLAID 4971
Query 5258 AYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMY 5317
AYPL+KH N EY VF + L +++ L+ L +LD +SV L D T+++W+ FY +MY
Sbjct 4972 AYPLSKHDNPEYRRVFTVMLDWVKHLYKTLNQGVLDSFSVTLLEDATAKFWDESFYASMY 5031
Query 5318 TPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAP 5377
+VLQ+ G CV+C+SQT LRCG CIRRP LC KC YDHV+STSHK +L++ PYVC +
Sbjct 5032 EQSSVLQSAGLCVVCSSQTVLRCGDCIRRPMLCTKCAYDHVVSTSHKFILAITPYVCCSS 5091
Query 5378 GCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCD 5437
GC V+DVT+LYLGG+SY+C HKP +SFPLC++G VFGLYKN+ GS +V DFN +AT D
Sbjct 5092 GCGVSDVTKLYLGGLSYWCVDHKPRLSFPLCSSGNVFGLYKNSATGSPDVDDFNTLATSD 5151
Query 5438 WTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPR 5497
WT+ DY LAN + L+LFAAET+KA EE+ K SY AT+ EV+ +EL L WEVGKPR
Sbjct 5152 WTDVKDYKLANDVKDSLRLFAAETIKAKEESVKSSYACATIHEVVGPKELVLKWEVGKPR 5211
Query 5498 PPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDY-GDAVVYRGTTTYKLNVGDYFVLTSHTV 5556
PPL+RN VFT Y +TKN+K Q+GE+TFEK DY DAV Y+ T T KL G FVLTSH V
Sbjct 5212 PPLSRNSVFTCYHITKNTKFQVGEFTFEKLDYDNDAVSYKSTATTKLVPGMVFVLTSHNV 5271
Query 5557 MPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFA 5616
PL APT++ QE Y + L P NI +++S+ + YQ +G QK +T+QGPPG+GKSH
Sbjct 5272 QPLRAPTIINQERYSTLHKLRPAFNIHEDYSNLIPYYQLIGKQKLTTIQGPPGSGKSHCV 5331
Query 5617 IGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTL 5676
IGL LY+P ARIV+TACSHAAVD+LC KA D+CSRIIP +AR+EC+D FK N+T
Sbjct 5332 IGLGLYFPGARIVFTACSHAAVDSLCVKAATAYSSDRCSRIIPQKARIECYDGFKSNNTS 5391
Query 5677 EQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLL 5736
QY+F TVNALPE ADI V DE+SM TNYDLSV+N R+ +H VY+GDP QLPAPR ++
Sbjct 5392 AQYLFSTVNALPEVNADICVVDEVSMCTNYDLSVINQRVNYRHIVYVGDPQQLPAPRVMI 5451
Query 5737 TKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCF 5796
T+G L PE +N V R M + PD+FL C RCPAEIV+TVS +VY+N+ K +S +CF
Sbjct 5452 TRGVLVPEDYNVVTRRMCVLKPDIFLHKCYRCPAEIVNTVSEMVYENQFVPVKSESKECF 5511
Query 5797 KMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQT 5856
K++ +G + D S+INR Q+ VVR FL +NP W KAVFISPYNSQN VA ++LGL QT
Sbjct 5512 KIYCRGNVQVDNGSSINRRQLEVVRMFLAKNPKWAKAVFISPYNSQNYVAGRVLGLQIQT 5571
Query 5857 VDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEI 5916
VDSSQGSEYDYVI+TQT++TAH+ NVNRFNVAITRAK GILCIM DR+L+D L+F L++
Sbjct 5572 VDSSQGSEYDYVIYTQTSDTAHASNVNRFNVAITRAKKGILCIMCDRELFDILKFYELKL 5631
Query 5917 PRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTE-GLCVDIPGIPKDMT 5975
+ LQ + GLFKDC K L P+ APT +S+ FKT+ L V I G+ +
Sbjct 5632 -----SDLQVGDGCGLFKDCYKGEDNLPPSHAPTFMSLSDNFKTDKDLAVQI-GVNGPVK 5685
Query 5976 YRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLG 6035
Y +IS MGF+ + V +F TR+ A+R+ R W+GFDVEG H VGTN+PLQLG
Sbjct 5686 YEHVISFMGFRFDINVPNQHTLFCTRDFAMRNARGWLGFDVEGAHVIGSNVGTNVPLQLG 5745
Query 6036 FSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQML 6095
FS GV+ V P G V T V A+ PPGDQF HL+PL+ KG PW+V+R +IVQM
Sbjct 5746 FSNGVDFVVRPEGCVSTEVGDVIQPVRARAPPGDQFTHLLPLLRKGQPWSVIRRRIVQMC 5805
Query 6096 SDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHS 6155
SD L NLSD ++FVLW+ G ELT+M+YFVK+GP +T C C +RATC+++ + T++C+ H+
Sbjct 5806 SDYLANLSDTLIFVLWSGGLELTTMRYFVKLGPVQT-CDCGKRATCYNSTNHTFSCFRHA 5864
Query 6156 IGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRV 6215
+G DY+YN + ID+QQWG+TG+L NH C +H N HVAS DA MTRCLA+H+CFVK V
Sbjct 5865 LGSDYIYNCYCIDIQQWGYTGSLSMNHHEVCNIHRNEHVASGDAAMTRCLAIHDCFVKNV 5924
Query 6216 DWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKF 6275
DW+I YP I +E IN + R VQ V++A L +HD+GNPK I+CV D W
Sbjct 5925 DWSITYPFIANEQAINKSGRLVQSHVMRAVLKLYNPKAIHDVGNPKGIRCV-VTDASWYC 5983
Query 6276 YDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLN 6335
YD P + +E Y Y TH DG+CLFWNCNVD YP S+VCRFDTR+ S LN
Sbjct 5984 YDKNPTNTNVKMLE---YDYITHGQ--LDGLCLFWNCNVDMYPEFSVVCRFDTRMRSTLN 6038
Query 6336 LPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKS 6395
L GC+GGSLYVN HAFHTPA+DK AF LK +PFF+Y DS CE ++ ++YVPL++
Sbjct 6039 LEGCNGGSLYVNNHAFHTPAYDKRAFAKLKAMPFFFYDDSECE----KLQDAVNYVPLRA 6094
Query 6396 ATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF--TRLQS 6453
+ CITRCN+GGAVC H Y Y+ AYN +AGF++WV FD +NLW TF + +Q
Sbjct 6095 SNCITRCNVGGAVCSKHCALYHNYVMAYNTFTTAGFTIWVPNSFDMFNLWQTFKNSNVQG 6154
Query 6454 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGV-DVELFENKTTLPVNVAFELWAK 6512
LEN+A+NVV KG F G +GE+PV+++N+ V + DGV D +F N T+LP NVAFEL+AK
Sbjct 6155 LENIAYNVVKKGSFVGVEGELPVAVVNDKVMVR-DGVSDNVVFVNNTSLPTNVAFELYAK 6213
Query 6513 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 6572
R + P + IL NLGV + V+WDY+ P T VC TD +
Sbjct 6214 RKVGLTPPLTILKNLGVVCTSKCVLWDYEASRPLTTFTKDVCKYTDFD--------GDVC 6265
Query 6573 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNY-Y 6631
FD V G + F +N VLI+ +VK L ++ LNGV + K Y Y
Sbjct 6266 TLFDNSVPGAFERFTVTKNAVLISLTAVKKLT-AIKLTYGYLNGVPVFTHEDKPFTWYIY 6324
Query 6632 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 6691
+ DG + P+ YFTQ R + +F+PRS ME DFL + M FI +Y LE Y FEH+V+GD
Sbjct 6325 TRKDGAFVEYPDGYFTQGRVISDFQPRSNMEEDFLNMDMGLFISKYGLEDYGFEHVVFGD 6384
Query 6692 FSHSQLGGLHLLIGLAKRFKESPFELEDFI-PMDSTVKNYFITDAQTGSSKCVCSVIDLL 6750
S + LGGLHLLI + K ++EDF+ DST+K+ +T SSK VC+ +DLL
Sbjct 6385 VSKTTLGGLHLLISQIRLSKIGVLKVEDFVSSSDSTLKSCTVTYVDNPSSKMVCTYVDLL 6444
Query 6751 LDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMP 6810
LDDFV I+KS DLSVVSKV +V ID +MLWCKD V+TFYP+LQS++ W+ G +MP
Sbjct 6445 LDDFVNILKSVDLSVVSKVHEVVIDCKVWRWMLWCKDHKVQTFYPQLQSAE-WKCGYSMP 6503
Query 6811 NLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGA 6870
++YK+QRM LE C+L NYG LP GIM NV KYTQLCQYLN+ T+ VP++MRV+H GA
Sbjct 6504 SIYKIQRMCLEPCNLYNYGSGLKLPDGIMFNVVKYTQLCQYLNSTTMCVPHHMRVLHLGA 6563
Query 6871 GSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY 6930
GSDKGVAPGTAVLR+WLP ++VD+D+ND+VSDAD + GDCA+++ +K+DL+ISDMY
Sbjct 6564 GSDKGVAPGTAVLRRWLPLDAVIVDNDVNDYVSDADFSYTGDCASMYLTDKFDLVISDMY 6623
Query 6931 DPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTA 6990
D +TK+ +N SKEGFF YI G I +KLALGG+VAIKITE SWN LY+L+ F +WT
Sbjct 6624 DGRTKSCDGDNVSKEGFFPYINGVITEKLALGGTVAIKITEFSWNKKLYELIQKFEYWTL 6683
Query 6991 FVTNVNASSSEAFLIGCNYLG--KPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKF 7048
F T+VN SSSEAFLIG ++LG IDG +MHANYIFWRN+ + +S S+ D+SKF
Sbjct 6684 FCTSVNTSSSEAFLIGVHFLGDFSTNAIIDGNIMHANYIFWRNSTIMTMSYNSVLDLSKF 6743
Query 7049 PLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVNN 7096
K + T V++LK+ + D++L LL G+L+IR N V S+ LVN+
Sbjct 6744 SCKHKATVVVNLKDSSVTDLVLGLLKNGKLLIRNNGVVCGFSNHLVNS 6791
Score = 75.5 bits (184), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 65/204 (32%), Positives = 94/204 (46%), Gaps = 16/204 (8%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLH 1116
VVNAAN L HGGG+A AL+ T +QV S+ Y++ NG +KVG ++ L+
Sbjct 1323 VVNAANEQLSHGGGIAKALDDLTKGELQVLSNQYVSRNGSIKVGSGVLIKCKE--HSILN 1380
Query 1117 VVGPNVNKGEDIQLLKSAYE-NFNQHEVLLAPLLSAGIFGADPIHSLR---VCVDTVRTN 1172
VVGP K +LL AY F Q V L PLLS GIF SL CV
Sbjct 1381 VVGPRKGK-HAAELLTKAYTFVFKQKGVPLMPLLSVGIFKVPITESLAAFLACVGDRVCK 1439
Query 1173 VYLAVFDKNL-YDKLVSSFLEMKSEKQVE-----QKIAEIPKEEVKPFITESKPSVEQRK 1226
+ + L V+SF ++E+ VE Q++ + E+ P + P R
Sbjct 1440 CFCYTDKERLAIQNFVTSF---QTEQPVEPLPVIQEVKGVQLEKPVPDVKVENPCEPFRI 1496
Query 1227 QDDKKIKACVEEVTTTLEETKFLT 1250
+ D K + +L+ T+ ++
Sbjct 1497 EGDAKFYDLTPSMVQSLQVTRLVS 1520
Score = 61.6 bits (148), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 54/206 (26%), Positives = 87/206 (42%), Gaps = 12/206 (6%)
Query 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
+L E + ++V T D + HT + S TYGQQ G ++ VT +KP + + + V
Sbjct 1634 TLFEAKPVQVVVTQDQRSFHTVELSTSQTYGQQLGDCVVEDKKVTNLKPVSKDKVVS--V 1691
Query 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTK-KWKYPQVNGLTSIKWADNNCYLATA 1679
+PN V+ ++Y D L+HT + VNG ++ +DNNC++
Sbjct 1692 VPN-----VDWDKHYGFVDAGIF----HTLDHTMFVFDNNVVNGKRVLRTSDNNCWINAV 1742
Query 1680 LLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHA 1739
L LQ KF P LQ + G+ A F + GE D T++ + +
Sbjct 1743 CLQLQFANAKFKPKGLQQLWESYCTGDVAMFVHWLYWITGVEKGEPSDAENTLNIISRFL 1802
Query 1740 NLDSCKRVLNVVCKTCGQQQTTLKGV 1765
+L TC +T + V
Sbjct 1803 KPQGSVEMLRATSTTCDGTCSTKRVV 1828
>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729
Score = 4306 bits (11167), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2299/4891 (47%), Positives = 3093/4891 (63%), Gaps = 220/4891 (4%)
Query 2263 CTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISS-FKWDLTAF 2321
C GY ST YC S+ C +CL + + I L F
Sbjct 1999 CGDIVSGYEKST-FNKDIYCGNSMVCKMCLFSYQEFNDLDHTSLVWKHIRDPILISLQPF 2057
Query 2322 GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMV 2381
++ + ++ RF + +A + F S+ H W + P +
Sbjct 2058 VILVILLIFGNMYLRFGLLYFVAQFISTFGSFLGFH--QKQWFL-------HFVPFDVLC 2108
Query 2382 RMYIFFASFYYVWKSYV---HVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYA 2438
F A+F V K + H++ GCN++ C+ C K R RV TI+NG+ +SFYV A
Sbjct 2109 NE--FLATFI-VCKIVLFVRHIIVGCNNADCVACSKSARLKRVPLQTIINGMHKSFYVNA 2165
Query 2439 NGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKN 2498
NGG FC HN+ CVNCD+F G+TFI+ ++AR+L K + PT + I+D V N
Sbjct 2166 NGGTCFCNKHNFFCVNCDSFGPGNTFINGDIARELGNVVKTAVQPTAPAYVIIDKVDFVN 2225
Query 2499 GSIHLY---------FDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKC 2549
G LY FD K + L + L+N N GS N+
Sbjct 2226 GFYRLYSGDTFWRYDFDITESKYSCKEVLKNCNVLENFIVYNNSGS---NI--------- 2273
Query 2550 EESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKL 2609
+ K+A VY+SQL+C+PI L++ L+S + S + + AYV+ ++F
Sbjct 2274 --TQIKNACVYFSQLLCEPIKLVNSELLSTL--SVDFNGVLHKAYVDVLCNSF------- 2322
Query 2610 KTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDS 2669
EL N+S+ +T G SD D V + +H+ D+ ++ S
Sbjct 2323 -------FKELTANMSMAECKATL------GLTVSD---DDFVSAVANAHRYDVLLSDLS 2366
Query 2670 CNNYMLTYNKVEN-MTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQ 2728
NN+ ++Y K E+ ++ D+ C+ ++ +N V +I ++W VKDF +LS++ +K
Sbjct 2367 FNNFFISYAKPEDKLSVYDIACCMRAGSKVVNHNVLIKESIPIVWGVKDFNTLSQEGKKY 2426
Query 2729 IRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGG---KIVNNWLKQLIKVTLVFLFVAA 2785
+ K L F LT + + V T I K G K N+L V LFV A
Sbjct 2427 LVKTTKAKGLTFLLTFNDNQAITQVPATSIVAKQGAGFKRTYNFL------WYVCLFVVA 2480
Query 2786 IFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSY 2845
+F ++ + + T F +K I+ G + + C N +F+ W + G
Sbjct 2481 LFIGVSFIDYTTTVTSFHG--YDFKYIENGQLKVFEAPLHCVRNVFDNFNQWHEAKFGVV 2538
Query 2846 T-NDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHF-LPRVFSAVGNICYTPSKLI 2903
T N CP++ V R VVPG+P + G L F L F G +CY
Sbjct 2539 TTNSDKCPIVVGVSERIN--VVPGVPTNVYLV--GKTLVFTLQAAFGNTG-VCY------ 2587
Query 2904 EYTDFATS-ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSII 2962
++ TS C+ + CT + G V YCY+T+++EGS Y +L+P+ Y + +
Sbjct 2588 DFDGVTTSDKCIFNSACTRLEGLGGDNV-YCYNTDLIEGSKPYSTLQPNAYYKYDAKNYV 2646
Query 2963 QFPNTYLEG-SVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGV 3021
+FP G +R + T + YCR G C S GVC +W +N+ R G CG
Sbjct 2647 RFPEILARGFGLRTIRTLATRYCRVGECRDSHKGVCFGFD-KWYVNDG--RVDDGYICGD 2703
Query 3022 DAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFN 3081
++LL N+ + + +S ++ + A +T L + +F+R FG+ S+ V
Sbjct 2704 GLIDLLVNVLSIFSSSFSVVAMSGHMLFNFLFAAFITFLCFLVTKFKRVFGDLSYGV--- 2760
Query 3082 TLLFLMSFTVLCLTPVYS---------FLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMF 3132
FTV+C T + + F +Y++ LY F T +++ HI ++V +
Sbjct 2761 -------FTVVCATLINNISYVVTQNLFFMLLYAI--LYFVFTRTVRYAWIWHIAYIVAY 2811
Query 3133 TPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFNGVSF-STFEEAALCTFLLNKE 3188
L+P+W+ + S F N K ++ +F G F TFE AA TF+L+
Sbjct 2812 FLLIPWWLLTWF----SFAAFLELLPNVFKLKISTQLFEGDKFIGTFESAAAGTFVLDMR 2867
Query 3189 MYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDV 3248
Y +L + + + Y A YNKYKY+SG+ YR A HLAKA+ D++ +D+
Sbjct 2868 SYERLINTI--SPEKLKNYAASYNKYKYYSGSASEADYRCACYAHLAKAMLDYAKDHNDM 2925
Query 3249 LYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICT 3308
LY PP S S LQSG +KMA PSG VE C+V+V G+T LNG+WL D V CPRHVI
Sbjct 2926 LYSPPTISYNST-LQSGLKKMAQPSGCVERCVVRVCYGSTVLNGVWLGDTVTCPRHVIAP 2984
Query 3309 SEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVR 3368
S +L +Y+ HNF V V L V+G +M VL++KV +N TPK+ F
Sbjct 2985 STTVL-IDYDHAYSTMRLHNFSVSHNGVFLGVVGVTMHGSVLRIKVSQSNVHTPKHVFKT 3043
Query 3369 IQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYD-CVSFCYMHH 3427
++PG +F++LACY G SGV+ +R NFTIKGSF+NG+CGS G+N+ D V FCY+H
Sbjct 3044 LKPGDSFNILACYEGIASGVFGVNLRTNFTIKGSFINGACGSPGYNVRNDGTVEFCYLHQ 3103
Query 3428 MELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFT 3487
+EL +G H G+D G+ YG F D+ + Q + ++ NV+A+LYAA++NG RW+L
Sbjct 3104 IELGSGAHVGSDFTGSVYGNFDDQPSLQVESANLMLSDNVVAFLYAALLNGCRWWLCSTR 3163
Query 3488 TTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGS 3547
++ FN AM Y ++ V+ L+A+TG++V + AS++ L G G+ ILG
Sbjct 3164 VNVDGFNEWAMANGYTSVSS--VECYSILAAKTGVSVEQLLASIQHL-HEGFGGKNILGY 3220
Query 3548 ALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLY 3607
+ L DEFT +VV+Q GV QS + I G L ++ ++ W+ F +Y
Sbjct 3221 SSLCDEFTLAEVVKQMYGVNLQSG--KVIFGLKTMFLFSVFFTMF-------WAELF-IY 3270
Query 3608 ENA-------FLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
N P ++ +S MF+KHK FL +FLLP++ A +N V ++
Sbjct 3271 TNTIWINPVILTPIFCLLLFLSLVLTMFLKHKFLFLQVFLLPTVIATALYNCVL--DYYI 3328
Query 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
++ + + S+ ++ V + ++ L T R + + +++ + Y
Sbjct 3329 VKFLADHFNYNVSVLQMDVQGLVNVLVCLFVVFLHTWRFSKERFTHWFTYVCSLIAVAYT 3388
Query 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
+Y + M+ IS + Y G + V L+R IVF E +F + G+ ++ +
Sbjct 3389 YFYSGDFLSLLVMFLCAIS-SDWYIGAI--VFRLSRLIVFFSPE--SVFSVFGD-VKLTL 3442
Query 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
+VY GY Y+G+ NR+F+ T+GVYD+ VS EF+YM + GL P DA L
Sbjct 3443 VVYLICGYLVCTYWGILYWFNRFFKCTMGVYDFKVSAAEFKYMVANGLHAPHGPFDALWL 3502
Query 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
+ KLLG+GG CIK++TVQSK++D+KCT+VVLL L + + ++S WA CV LHN I L
Sbjct 3503 SFKLLGIGGDRCIKISTVQSKLTDLKCTNVVLLGCLSSMNIAANSSEWAYCVDLHNKINL 3562
Query 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
D +A +++LL+ LS ++ L + DN +TLQ++AS F S+PSY A+ A
Sbjct 3563 CDDPEKAQSMLLALLAFFLSKHSDFGLDGLIDSYFDNSSTLQSVASSFVSMPSYIAYENA 3622
Query 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
++AYE A+ANG S ++K+LK+++N+AKSEFD + ++Q+K+ +MA+QA TQMYK+ARS +
Sbjct 3623 RQAYEDAIANGSSSQLIKQLKRAMNIAKSEFDHEISVQKKINRMAEQAATQMYKEARSVN 3682
Query 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
+++KV SAM ++LF MLR+LD ++ ++N ARDG VPL++IP T+A+KL +V PD +Y
Sbjct 3683 RKSKVISAMHSLLFGMLRRLDMSSVETVLNLARDGVVPLSVIPATSASKLTIVSPDLESY 3742
Query 4081 -KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKL 4139
K CDG+ YA +W + V D D + V + EI+ +N L WPLI+ R VKL
Sbjct 3743 SKIVCDGSVH-YAGVVWTLNDVKDNDGRPVHVKEITKENVETLTWPLILNCERV---VKL 3798
Query 4140 QNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKS 4199
QNNE+ P L+Q A D NAL YNT G F+ A +S+ DLK+ ++
Sbjct 3799 QNNEIMPGKLKQKPMKAEGDGGVLGDGNAL--YNTEGGKTFMYAYISNKADLKFVKWEYE 3856
Query 4200 DGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATE 4259
G TI EL+ PCRF+ +TP GP+VKYLYF+K LN L RG VLG + AT+RLQAG TE
Sbjct 3857 GGCNTI--ELDSPCRFMVETPNGPQVKYLYFVKNLNTLRRGAVLGFIGATIRLQAGKQTE 3914
Query 4260 VPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQE 4319
+ NS +L+ CAF+VD A Y + + G +P++NC+KML G GQAIT + +AN +Q+
Sbjct 3915 LAVNSGLLTACAFSVDPATTYLEAVKHGAKPVSNCIKMLSNGAGNGQAITTSVDANTNQD 3974
Query 4320 SFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGY 4379
S+GGAS CLYCR H+ HP+ G+C KGK VQ+P C DP+ F L+N VC VCG W G+
Sbjct 3975 SYGGASICLYCRAHVPHPSMDGYCKFKGKCVQVPIGCL-DPIRFCLENNVCNVCGCWLGH 4033
Query 4380 GCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAK 4439
GC+CD+ +QS D S+LNR G SAARL PC GT D RAFDIYN V+ K
Sbjct 4034 GCACDR---TTIQSVDI-SYLNRARGSSAARLEPC-NGTDIDKCVRAFDIYNKNVSFLGK 4088
Query 4440 FLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRID 4499
LK NC RF+ D L D YFV+KR T S +HE+++YNLL A+A+HDFF ++ D
Sbjct 4089 CLKMNCVRFKNAD----LKDGYFVIKRCTKSVMEHEQSMYNLLNFSGALAEHDFFTWK-D 4143
Query 4500 GDMV-PHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFV 4558
G ++ ++SR LTKYTM DLVYA+R+FDE NCD LKE+LV CCD+ YF+ K WYD V
Sbjct 4144 GRVIYGNVSRHNLTKYTMMDLVYAMRNFDEQNCDVLKEVLVLTGCCDNSYFDSKGWYDPV 4203
Query 4559 ENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTT 4618
EN DI RVYA+LG+ V +A+LK V CDAM G+VGVLTLDNQDLNGN+YDFGDF+ +
Sbjct 4204 ENEDIHRVYASLGKIVARAMLKCVALCDAMVAKGVVGVLTLDNQDLNGNFYDFGDFVVSL 4263
Query 4619 PGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIK-WDLLKYDFTEERLKLFDR 4677
P GVP SYYS +MPI+ LT L +E V +D+ K +DLLKYDFTE + LF++
Sbjct 4264 PNMGVPCCTSYYSYMMPIMGLTNCLASECFVKSDIFGSDFKTFDLLKYDFTEHKENLFNK 4323
Query 4678 YFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTG 4737
YFK+W YHPNC +C DD C++HCANFN LF+T P T+FGPL RK+F+DGVP V + G
Sbjct 4324 YFKHWSFDYHPNCSDCYDDMCVIHCANFNTLFATTIPGTAFGPLCRKVFIDGVPLVTTAG 4383
Query 4738 YHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNV 4797
YHF++LG+V N+DVN HS RL+ ELL + DP++ AS L+D+RT CFSVAAL+ +
Sbjct 4384 YHFKQLGLVWNKDVNTHSVRLTITELLQFVTDPSLIIASSPALVDQRTICFSVAALSTGL 4443
Query 4798 AFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCD 4857
Q VKPG+FN++FY+F +GFF EGS + LKHFFFAQ+G+AA+ D+D+YRYN PT+ D
Sbjct 4444 TNQVVKPGHFNEEFYNFLRLRGFFDEGSELTLKHFFFAQNGDAAVKDFDFYRYNKPTILD 4503
Query 4858 IRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQD 4917
I Q ++V +YFD Y+GGCI A +V+V NL+KSAG+P NK+GKA LYY+S+SYE+QD
Sbjct 4504 ICQARVTYKIVSRYFDIYEGGCIKACEVVVTNLNKSAGWPLNKFGKASLYYESISYEEQD 4563
Query 4918 ALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGA 4977
ALFA TKRNV+PT+TQ+NLKYAIS K RARTV GVS+ STMT RQ+HQK LKSI TR A
Sbjct 4564 ALFALTKRNVLPTMTQLNLKYAISGKERARTVGGVSLLSTMTTRQYHQKHLKSIVNTRNA 4623
Query 4978 TVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTC 5037
TVVIGT+KFYGGW+NML+T+ VENP LMGWDYPKCDRA+PNM+R+++++VL KH C
Sbjct 4624 TVVIGTTKFYGGWNNMLRTLIDGVENPMLMGWDYPKCDRALPNMIRMISAMVLGSKHVNC 4683
Query 5038 CSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVN 5097
C+ + RFYRL NE AQVL+E+V G Y KPGGT+SGDA+TAYANS+FNI QAV++N+N
Sbjct 4684 CTATDRFYRLGNELAQVLTEVVYSNGGFYFKPGGTTSGDASTAYANSIFNIFQAVSSNIN 4743
Query 5098 ALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVC 5157
LLS + + VR+LQ RLY+ YR V+ F++++Y YLRKHFSMMILSDD VVC
Sbjct 4744 RLLSVPSDSCNNVNVRDLQRRLYDNCYRLTSVEESFIDDYYGYLRKHFSMMILSDDGVVC 4803
Query 5158 FNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDD 5217
+N YA G +A I FK+ LYYQNNVFMS +KCW E DLTKGPHEFCSQHTM + D
Sbjct 4804 YNKDYAELGYIADISAFKATLYYQNNVFMSTSKCWVEEDLTKGPHEFCSQHTMQIVDKDG 4863
Query 5218 YVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYL 5277
YLPYPDPSRIL AG FVDD+VKTD +++ER+VSLAIDAYPL+KHPN EY VF++ L
Sbjct 4864 TYYLPYPDPSRILSAGVFVDDVVKTDAVVLLERYVSLAIDAYPLSKHPNSEYRKVFYVLL 4923
Query 5278 QYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTS 5337
+++ L+ L +L+ +SV L ++ ++W +FY +MY T+LQA G CV+C SQT
Sbjct 4924 DWVKHLNKNLNEGVLESFSVTLLDNQEDKFWCEDFYASMYENSTILQAAGLCVVCGSQTV 4983
Query 5338 LRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCK 5397
LRCG C+R+P LC KC YDHV T HK +L++ PYVCNA GC V+DV +LYLGG++YYC
Sbjct 4984 LRCGDCLRKPMLCTKCAYDHVFGTDHKFILAITPYVCNASGCGVSDVKKLYLGGLNYYCT 5043
Query 5398 SHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLF 5457
+HKP +SFPLC+ G +FGLYKN+ GS +V FN +AT DWT+ DY LAN + L+LF
Sbjct 5044 NHKPQLSFPLCSAGNIFGLYKNSATGSLDVEVFNRLATSDWTDVRDYKLANDVKDTLRLF 5103
Query 5458 AAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKV 5517
AAET+KA EE+ K SY AT++EV+ +EL LSWE GK +PPLNRN VFT ++++K+SK
Sbjct 5104 AAETIKAKEESVKSSYAFATLKEVVGPKELLLSWESGKVKPPLNRNSVFTCFQISKDSKF 5163
Query 5518 QIGEYTFEKGDYG-DAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGL 5576
QIGE+ FEK +YG D V Y+ T T KL G FVLTSH V PL APT+ QE Y I L
Sbjct 5164 QIGEFIFEKVEYGSDTVTYKSTVTTKLVPGMIFVLTSHNVQPLRAPTIANQEKYSSIYKL 5223
Query 5577 YPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHA 5636
+P N+SD +++ V YQ +G QK +T+QGPPG+GKSH +IGL LYYP ARIV+ AC+HA
Sbjct 5224 HPAFNVSDAYANLVPYYQLIGKQKITTIQGPPGSGKSHCSIGLGLYYPGARIVFVACAHA 5283
Query 5637 AVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVV 5696
AVD+LC KA+ IDKC+RIIPARARVEC+ FK N+T QY+F TVNALPE ADIVV
Sbjct 5284 AVDSLCAKAMTVYSIDKCTRIIPARARVECYSGFKPNNTSAQYIFSTVNALPECNADIVV 5343
Query 5697 FDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTI 5756
DE+SM TNYDLSV+N RL KH VY+GDP QLPAPR ++TKG +EP +N V + M I
Sbjct 5344 VDEVSMCTNYDLSVINQRLSYKHIVYVGDPQQLPAPRVMITKGVMEPVDYNVVTQRMCAI 5403
Query 5757 GPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQ 5816
GPD+FL C RCPAEIV+TVS LVY+NK K S QCFK+F+KG + D S+INR Q
Sbjct 5404 GPDVFLHKCYRCPAEIVNTVSELVYENKFVPVKPASKQCFKVFFKGNVQVDNGSSINRKQ 5463
Query 5817 IGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTET 5876
+ +V+ FL +NP+W KAVFISPYNSQN VAS+ LGL QTVDSSQGSEYDYVI+ QT++T
Sbjct 5464 LEIVKLFLVKNPSWSKAVFISPYNSQNYVASRFLGLQIQTVDSSQGSEYDYVIYAQTSDT 5523
Query 5877 AHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDC 5936
AH+CNVNRFNVAITRAK GI C+M D+ L+D L+F EI A L + V GLFK+C
Sbjct 5524 AHACNVNRFNVAITRAKKGIFCVMCDKTLFDSLKF--FEIKH---ADLHSSQVCGLFKNC 5578
Query 5937 SKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYP 5995
++ L PT A T LS+ +FKT G L V I G TY +IS MGF+ + + G
Sbjct 5579 TRTPLNLPPTHAHTFLSLSDQFKTTGDLAVQI-GSNNVCTYEHVISFMGFRFDISIPGSH 5637
Query 5996 NMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNN 6055
++F TR+ AIR+VR W+G DVE H + +GTN+PLQ+GFS GVN V G V T
Sbjct 5638 SLFCTRDFAIRNVRGWLGMDVESAHVCGDNIGTNVPLQVGFSNGVNFVVQTEGCVSTNFG 5697
Query 6056 TDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGF 6115
V AK PPG+QF+HLIPL+ KG PW +VR +IVQM+SD L NLSD +VFVLWA
Sbjct 5698 DVIKPVCAKSPPGEQFRHLIPLLRKGQPWLIVRRRIVQMISDYLSNLSDILVFVLWAGSL 5757
Query 6116 ELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFT 6175
ELT+M+YFVKIGP + C C ATC+++ S+ Y C+ H++G DYVYNP+ D+QQWG+
Sbjct 5758 ELTTMRYFVKIGPIKY-CYCGNSATCYNSVSNEYCCFKHALGCDYVYNPYAFDIQQWGYV 5816
Query 6176 GNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACR 6235
G+L NH +C +H N H AS DA+MTRCLAVH+CFVK VDWT+ YP I +E IN R
Sbjct 5817 GSLSQNHHTFCNIHRNEHDASGDAVMTRCLAVHDCFVKNVDWTVTYPFIANEKFINGCGR 5876
Query 6236 KVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSY 6295
VQ VV+AAL K V+HDIGNPK ++C D +W YD QP + ++ L Y Y
Sbjct 5877 NVQGHVVRAALKLYKPSVIHDIGNPKGVRCA-VTDAKWYCYDKQPVNS---NVKLLDYDY 5932
Query 6296 ATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPA 6355
ATH DG+CLFWNCNVD YP SIVCRFDTR S NL G +GGSLYVNKHAFHTPA
Sbjct 5933 ATHGQ--LDGLCLFWNCNVDMYPEFSIVCRFDTRTRSVFNLEGVNGGSLYVNKHAFHTPA 5990
Query 6356 FDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANE 6415
+DK AFV LK +PFFY+ DS C+ +QV +YVPL++++C+TRCN+GGAVC HAN
Sbjct 5991 YDKRAFVKLKPMPFFYFDDSDCDVVQEQV----NYVPLRASSCVTRCNIGGAVCSKHANL 6046
Query 6416 YRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF--TRLQSLENVAFNVVNKGHFDGQQGE 6473
Y+ Y++AYN AGF++WV FD YNLW F T LQSLEN+AFNVV KG F G GE
Sbjct 6047 YQKYVEAYNTFTQAGFNIWVPHSFDVYNLWQIFIETNLQSLENIAFNVVKKGCFTGVDGE 6106
Query 6474 VPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAA 6533
+PV+++N+ V+ + VD +F NKTTLP NVAFEL+AKR + P + IL NLGV
Sbjct 6107 LPVAVVNDKVFVRYGDVDNLVFTNKTTLPTNVAFELFAKRKMGLTPPLSILKNLGVVATY 6166
Query 6534 NTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGV 6593
V+WDY+ + P T VC TD E +C V FD + G + F N V
Sbjct 6167 KFVLWDYEAERPFTSYTKSVCKYTDF----NEDVC----VCFDNSIQGSYERFTLTTNAV 6218
Query 6594 LITEGSVKGLQPSVGPKQASLNGVTLIG----EAVKTQFNYYKKV--DGVVQQLPETYFT 6647
L + +K L P + LNG+ + + V+ N+Y V +G Q + ++T
Sbjct 6219 LFSTVVIKNLTP-IKLNFGMLNGMPVSSIKGDKGVEKLVNWYIYVRKNGQFQDHYDGFYT 6277
Query 6648 QSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLA 6707
Q RNL +F PRS ME DFL + M FI +Y LE + FEH+VYGD S + LGGLHLLI
Sbjct 6278 QGRNLSDFTPRSDMEYDFLNMDMGVFINKYGLEDFNFEHVVYGDVSKTTLGGLHLLISQF 6337
Query 6708 KRFKESPFELEDFIPM-DSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVV 6766
+ K + +DF+ D+T++ +T SSK VC+ +DLLLDDFV I+KS DL V+
Sbjct 6338 RLSKMGVLKADDFVTASDTTLRCCTVTYLNELSSKVVCTYMDLLLDDFVTILKSLDLGVI 6397
Query 6767 SKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQ 6826
SKV +V ID +MLWCKD H+ TFYP+LQS++ W+ G AMP +YK+QRM LE C+L
Sbjct 6398 SKVHEVIIDNKPYRWMLWCKDNHLSTFYPQLQSAE-WKCGYAMPQIYKLQRMCLEPCNLY 6456
Query 6827 NYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQW 6886
NYG LP GIM+NV KYTQLCQYLN+ T+ VP+NMRV+H+GAGSDKGVAPGT VL++W
Sbjct 6457 NYGAGIKLPSGIMLNVVKYTQLCQYLNSTTMCVPHNMRVLHYGAGSDKGVAPGTTVLKRW 6516
Query 6887 LPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEG 6946
LP +++D+D+ND+VSDAD ++ GDCATV+ +K+DL+ISDMYD + K EN SK+G
Sbjct 6517 LPPDAIIIDNDINDYVSDADFSITGDCATVYLEDKFDLLISDMYDGRIKFCDGENVSKDG 6576
Query 6947 FFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIG 7006
FFTY+ G I++KLA+GGSVAIKITE+SWN LY+L+ FA+WT F T+VN SSSEAFLIG
Sbjct 6577 FFTYLNGVIREKLAIGGSVAIKITEYSWNKYLYELIQRFAFWTLFCTSVNTSSSEAFLIG 6636
Query 7007 CNYLGKPREQ--IDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQ 7064
NYLG + I G +HANYIFWRN+ + LS S+ D+SKF K + T V++LK+
Sbjct 6637 INYLGDFIQGPFIAGNTVHANYIFWRNSTIMSLSYNSVLDLSKFECKHKATVVVTLKDSD 6696
Query 7065 INDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
+NDM+LSL+ GRL++R N R S+ LV+
Sbjct 6697 VNDMVLSLIKSGRLLLRNNGRFGGFSNHLVS 6727
Score = 80.9 bits (198), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 55/144 (38%), Positives = 74/144 (51%), Gaps = 6/144 (4%)
Query 1020 VQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKAT 1079
++ EV F+ Y NV DI V VVNAAN L HGGGVA A++ T
Sbjct 1252 IEAGEVKPFAVY----KNVKFYLGDISHLVNCVSFDFVVNAANENLLHGGGVARAIDILT 1307
Query 1080 NNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFN 1139
+Q S DYI++NGPLKVG +L + +VVGP K E L+++
Sbjct 1308 EGQLQSLSKDYISSNGPLKVGAGVMLECEKF--NVFNVVGPRTGKHEHSLLVEAYNSILF 1365
Query 1140 QHEVLLAPLLSAGIFGADPIHSLR 1163
++ + L PLLS GIFG +SL+
Sbjct 1366 ENGIPLMPLLSCGIFGVRIENSLK 1389
Score = 51.2 bits (121), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 50/174 (29%), Positives = 72/174 (41%), Gaps = 16/174 (9%)
Query 1573 TVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLP-NDDTLRVEA 1631
T D IN+ VV+ S + G+Q G DG D S EG VLP N DT+ A
Sbjct 1587 TEDGINVKDVVVESSKSLGKQLGVVS-DGVD--------SFEG----VLPINTDTVLSVA 1633
Query 1632 FEYYHTTDPSFLGRYMSALNHTKKWKYPQ--VNGLTSIKWADNNCYLATALLTLQQIELK 1689
E F + A K + YP V G + DNNC++ + LQ ++
Sbjct 1634 PEVDWVAFYGFEKAALFASLDVKPYGYPNDFVGGFRVLGTTDNNCWVNATCIILQYLKPT 1693
Query 1690 FNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDS 1743
F L + + G+ F + I + G+ GD E +S L ++ DS
Sbjct 1694 FKSKGLNVLWNKFVTGDVGPFVSFIYFITMSSKGQKGDAEEALSKLSEYLISDS 1747
Score = 38.5 bits (88), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 42/176 (24%), Positives = 72/176 (41%), Gaps = 13/176 (7%)
Query 1663 GLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV 1722
G+ + +DNNC+++T L+ LQ +L + +Q + G+ + +
Sbjct 1051 GVRVLDQSDNNCWISTTLVQLQLTKLLDDSIEMQ----LFKVGKVDSIVQKCYELSHLIS 1106
Query 1723 GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKG 1782
G LGD + +S L + +C + C CG++ G ++ + F+KG
Sbjct 1107 GSLGDSGKLLSELLKEKY--TCSITFEMSCD-CGKKFDDQVG---CLFWIMPYTKLFQKG 1160
Query 1783 VQIPCTCGKQATKYLVQQESPFVMMSAP-PAQYELKHGTFTCASEYTGNYQCGHYK 1837
C C K T LV + V + P P + C+S Y G GHY+
Sbjct 1161 E--CCICHKMQTYKLVSMKGTGVFVQDPAPIDIDAFPVKPICSSVYLGVKGSGHYQ 1214
>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781
Score = 4290 bits (11126), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2276/4910 (46%), Positives = 3101/4910 (63%), Gaps = 195/4910 (4%)
Query 2230 IIWFLLLS-VCLG-SLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIP 2287
+ WF +L LG +Y+ + + + +G P C GY NS+ YC S+
Sbjct 2020 LYWFKVLGKFSLGIYALYALLFMTIRFTPIGSP-VCDDVVAGYANSS-FDKNEYCN-SVI 2076
Query 2288 CSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIM 2347
C VCL G L + + + W L+ FFY+ LA
Sbjct 2077 CKVCLYGYQELSDFSHTQVV--------WQHLRDPLIGN-------VMPFFYLAFLAIFG 2121
Query 2348 QLFFSYFAVHFIS---NSWLMWL----IINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
++ ++FI NS ++L I +Q+ P + F V HV
Sbjct 2122 GVYVKAITLYFIFQYLNSLGVFLGLQQSIWFLQLVPFDVFGDEIVVFFIVTRVLMFIKHV 2181
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GC+ ++C+ C K R RV TI G +SFYV+ANGG FCK HN+ C+NCD++
Sbjct 2182 CLGCDKASCVACSKSARLKRVPVQTIFQGTSKSFYVHANGGSKFCKKHNFFCLNCDSYGP 2241
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G TFI+D +A ++ K + PT ++ ++D V NG +LY K + S
Sbjct 2242 GCTFINDVIATEVGNVVKLNVQPTGPATILIDKVEFSNGFYYLYSGDTFWKYNFDITDSK 2301
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
+ + L+ S+ + IVF+ + K+A VY+SQ++C+P+ L+D AL++ +
Sbjct 2302 YTCKEALK----NCSIITDFIVFNNNGS-NVNQVKNACVYFSQMLCKPVKLVDSALLASL 2356
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNV-LSTFISAARQ 2639
S + + A+V+ S++F + + + + D+V L TF +A +
Sbjct 2357 --SVDFGASLHSAFVSVLSNSFGKDLSSCNDM-----QDCKSTLGFDDVPLDTFNAAVAE 2409
Query 2640 GFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTP-RDLGACIDCSARH 2698
+H+ D+ +T S NN+ +Y K E P D+ C+ A+
Sbjct 2410 ------------------AHRYDVLLTDMSFNNFTTSYAKPEEKFPVHDIATCMRVGAKI 2451
Query 2699 INAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKI 2758
+N V +I ++W V+DF++LSE+ RK I K + F LT R + T I
Sbjct 2452 VNHNVLVKDSIPVVWLVRDFIALSEETRKYIIRTTKVKGITFMLTFNDCRMHTTIPTVCI 2511
Query 2759 ALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEI-----IGYKAID 2813
A K G + ++ K + LF+ A F+ ++ DFS+++ +K I+
Sbjct 2512 ANKKGAGLPSFSKVKKFFWFLCLFIVAAFFALS-------FLDFSTQVSSDSDYDFKYIE 2564
Query 2814 GGVTRDIASTDTCFANKHADFDTWFSQRGG-SYTNDKACPLIAAVITREVGFVVPGLPGT 2872
G + + +C N +FD W + G + N+ +CP++ V + VPG+P
Sbjct 2565 SGQLKTFDNPLSCVHNVFINFDQWHDAKFGFTPVNNPSCPIVVGV--SDEARTVPGIPAG 2622
Query 2873 ILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPY 2932
+ G L F +C+ S + + AC+ + CT G V Y
Sbjct 2623 VYLA--GKTLVFAINTIFGTSGLCFDASGVAD-----KGACIFNSACTTLSGLGGTAV-Y 2674
Query 2933 CYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCER 2991
CY ++EG+ Y L P + Y ++DG+ + P G +R + T YCR G C +
Sbjct 2675 CYKNGLVEGAKLYSELAPHSYYKMVDGNAVSLPEIISRGFGIRTIRTKAMTYCRVGQCVQ 2734
Query 2992 SEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGG 3051
S GVC +V N + S CG LL N+ + + + +S I+
Sbjct 2735 SAEGVCFGADRFFVYNAE---SGSDFVCGTGLFTLLMNVISVFSKTVPVTVLSGQILFNC 2791
Query 3052 IVAIVVTCLAYYFMRFRRAFGEYS---HVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVI 3108
I+A V + + F +F+R FG+ S V TLL +S+ V T + +
Sbjct 2792 IIAFVAVAVCFLFTKFKRMFGDMSVGVFTVGACTLLNNVSYIVTQNT--------LGMLG 2843
Query 3109 YLYLTFYLTNDVSFLA--HIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV- 3165
Y L F T V ++ H+ +++ + + P+W+ + Y + + F N K +V
Sbjct 2844 YATLYFLCTKGVRYMWIWHLGFLISYILIAPWWVLMVY----AFSAIFEFMPNLFKLKVS 2899
Query 3166 --VFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMD 3222
+F G F +FE AA TF+L+ Y +L + + + +Y + YNKYKY+SG+
Sbjct 2900 TQLFEGDKFVGSFENAAAGTFVLDMHAYERLANSI--STEKLRQYASTYNKYKYYSGSAS 2957
Query 3223 TTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQ 3282
YR A HLAKA+ D++++ +D LY PP S S LQ+G RKMA PSG VE C+V+
Sbjct 2958 EADYRLACFAHLAKAMMDYASNHNDTLYTPPTVSYNST-LQAGLRKMAQPSGVVEKCIVR 3016
Query 3283 VTCGTTTLNGLWLDDVVYCPRHVICTSE-DMLNPNYEDLLIRKSNHNFLVQAGNVQLRVI 3341
V G LNGLWL D+V CPRHVI +S ++ +Y ++R HNF + +GNV L V+
Sbjct 3017 VCYGNMALNGLWLGDIVMCPRHVIASSTTSTIDYDYALSVLRL--HNFSISSGNVFLGVV 3074
Query 3342 GHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKG 3401
+M+ +L++KV+ N TPKY + ++PG++F++LACY+G+ +GVY MR N+TI+G
Sbjct 3075 SATMRGALLQIKVNQNNVHTPKYTYRTVRPGESFNILACYDGAAAGVYGVNMRSNYTIRG 3134
Query 3402 SFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDT 3461
SF+NG+CGS G+NI+ V FCY+H +EL +G H G+DL+G YG + D+ T Q G +
Sbjct 3135 SFINGACGSPGYNINNGTVEFCYLHQLELGSGCHVGSDLDGVMYGGYEDQPTLQVEGASS 3194
Query 3462 TITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTG 3521
T NVLA+LYAA+ING W+L+ ++ FN A+ T + D L+A+TG
Sbjct 3195 LFTENVLAFLYAALINGSTWWLSSSRIAVDRFNEWAVHNGMT--TVGNTDCFSILAAKTG 3252
Query 3522 IAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSA-VKRTIKGTH 3580
+ V + AS++ L +N G+ ILG L DEFT +VVRQ GV Q V R +
Sbjct 3253 VDVQRLLASIQSLHKN-FGGKQILGHTSLTDEFTTGEVVRQMYGVNLQGGYVSRACRN-- 3309
Query 3581 HWLLLTILTSLLVLVQS--TQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCL 3638
+ ++ S L S ++ FF++ P + +S+ M +KHK F +
Sbjct 3310 ----VLLVGSFLTFFWSELVSYTKFFWVNPGYVTPMFACLSLLSSLLMFTLKHKTLFFQV 3365
Query 3639 FLLPSLATVAYFNMVYMPASWVMRIMTWL-DMVD--TSLSGFKLKDCVMYASAVVLLILM 3695
FL+P+L + N+ + + + +L + D SL GF + V V+ IL
Sbjct 3366 FLIPALIVTSCINLAFD-----VEVYNYLAEHFDYHVSLMGFNAQGLVNIFVCFVVTILH 3420
Query 3696 TART--VYDDGARRVWTLMNVLTLVYKVYYG-NALDQAISMWALIISVTSNYSGVVTTVM 3752
T ++ A V ++ +LT Y +Y + L A++++A SVT N+ V V
Sbjct 3421 GTYTWRFFNTPASSVTYVVALLTAAYNYFYASDILSCAMTLFA---SVTGNW--FVGAVC 3475
Query 3753 FLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYD 3812
+ + V+M + + P F ++ +M Y LGYF C++G+ NR+F++++GVYD
Sbjct 3476 Y--KVAVYMALRF-PTFVAIFGDIKSVMFCYLVLGYFTCCFYGILYWFNRFFKVSVGVYD 3532
Query 3813 YLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVL 3872
Y VS EF+YM + GL P ++D+ L+ KL+G+GG+ IK+++VQSK++D+KC++VVL
Sbjct 3533 YTVSAAEFKYMVANGLRAPTGTLDSLLLSAKLIGIGGERNIKISSVQSKLTDIKCSNVVL 3592
Query 3873 LSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCE 3932
L L + V ++S WA CV LHN I L D +A E +++LL+ LS A ++ L E
Sbjct 3593 LGCLSSMNVSANSTEWAYCVDLHNKINLCNDPEKAQEMLLALLAFFLSKNSAFGLDDLLE 3652
Query 3933 EMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFD 3992
++ + LQ++AS + LPSY + A++ YE AV NG ++K+L+ ++NVAKSEFD
Sbjct 3653 SYFNDNSMLQSVASTYVGLPSYVIYENARQQYEDAVNNGSPPQLVKQLRHAMNVAKSEFD 3712
Query 3993 RDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNA 4052
R+A+ QRKL++MA+QA QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I+N A
Sbjct 3713 REASTQRKLDRMAEQAAAQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNLA 3772
Query 4053 RDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLS 4112
+DG VPL++IP +A KL +V D ++Y YA +W I + D D K+V +
Sbjct 3773 KDGVVPLSVIPAVSATKLNIVTSDIDSYNRIQREGCVHYAGTIWNIIDIKDNDGKVVHVK 3832
Query 4113 EISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYY 4172
E++ N+ +L+WPL++ R VKLQNNE+ P L+Q S A A Y
Sbjct 3833 EVTAQNAESLSWPLVLGCERI---VKLQNNEIIPGKLKQRSIKAEGDGIV---GEGKALY 3886
Query 4173 NTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIK 4232
N G F+ A +SD DL+ ++ G TI ELEPP +F+ D+P G ++KYLYF++
Sbjct 3887 NNEGGRTFMYAFISDKPDLRVVKWEFDGGCNTI--ELEPPRKFLVDSPNGAQIKYLYFVR 3944
Query 4233 GLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPIT 4292
LN L RG VLG + ATVRLQAG TE NS++L+ CAFAVD AK Y D + SG +P+
Sbjct 3945 NLNTLRRGAVLGYIGATVRLQAGKQTEQAINSSLLTLCAFAVDPAKTYIDAVKSGHKPVG 4004
Query 4293 NCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQI 4352
NCVKML +G GQA+T EA+ +Q+S+GGAS CLYCR H++HP+ GFC LKGKYVQ+
Sbjct 4005 NCVKMLANGSGNGQAVTNGVEASTNQDSYGGASVCLYCRAHVEHPSMDGFCRLKGKYVQV 4064
Query 4353 PTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLT 4412
P DP+ F L+N VC VCG W GC+CD+ ++QS D ++LNRV G SAARL
Sbjct 4065 PLGTV-DPIRFVLENDVCKVCGCWLSNGCTCDR---SIMQSTD-MAYLNRVRGSSAARLE 4119
Query 4413 PCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNY 4472
PC GT T VYRAFDIYN VA KFLK NC R + D+ D +++VVKR T S
Sbjct 4120 PC-NGTDTQHVYRAFDIYNKDVACLGKFLKVNCVRLKNLDKHD----AFYVVKRCTKSAM 4174
Query 4473 QHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCD 4532
+HE++IY+ L+ C A+A+HDFF ++ + ++ R+ LT+YTM DL YALR+FDE NCD
Sbjct 4175 EHEQSIYSRLEKCGAIAEHDFFTWKDGRAIYGNVCRKDLTEYTMMDLCYALRNFDENNCD 4234
Query 4533 TLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAG 4592
LK IL+ C++ YFN K W+D VEN DI RVYA LG V +A+LK V+FCDAM G
Sbjct 4235 VLKSILIKVGACEESYFNNKVWFDPVENEDIHRVYALLGTIVARAMLKCVKFCDAMVEQG 4294
Query 4593 IVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTD 4652
IVGV+TLDNQDLNG++YDFGDF + G GVP+ SYYS +MP++ +T L +E V +D
Sbjct 4295 IVGVVTLDNQDLNGDFYDFGDFTCSIKGMGVPICTSYYSYMMPVMGMTNCLASECFVKSD 4354
Query 4653 L-TKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFST 4711
+ + + +DLL+YDFTE + LF++YFKYW YHPNCV+C D++CI+HCANFN LFST
Sbjct 4355 IFGEDFKSYDLLEYDFTEHKTALFNKYFKYWGLQYHPNCVDCSDEQCIVHCANFNTLFST 4414
Query 4712 VFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPA 4771
P T+FGPL RK ++DGVP V + GYHF++LG+V N D+NLHSSRLS ELL + +DPA
Sbjct 4415 TIPITAFGPLCRKCWIDGVPLVTTAGYHFKQLGIVWNNDLNLHSSRLSINELLQFCSDPA 4474
Query 4772 MHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKH 4831
+ AS L+D+RT CFSVAAL + QTVKPG+FNK+FYDF + +GFF EGS + LKH
Sbjct 4475 LLIASSPALVDQRTVCFSVAALGTGMTNQTVKPGHFNKEFYDFLLEQGFFSEGSELTLKH 4534
Query 4832 FFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLD 4891
FFFAQ +AA+ D+DYYRYN PT+ DI Q V ++V +YFD Y+GGCI A +V+V NL+
Sbjct 4535 FFFAQKVDAAVKDFDYYRYNRPTVLDICQARVVYQIVQRYFDIYEGGCITAKEVVVTNLN 4594
Query 4892 KSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAG 4951
KSAG+P NK+GKA LYY+S+SYE+QD L+AYTKRN++PT+TQ+NLKYAIS K RARTV G
Sbjct 4595 KSAGYPLNKFGKAGLYYESLSYEEQDELYAYTKRNILPTMTQLNLKYAISGKERARTVGG 4654
Query 4952 VSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDY 5011
VS+ STMT RQ+HQK LKSI TRGA+VVIGT+KFYGGW NMLK + VENP LMGWDY
Sbjct 4655 VSLLSTMTTRQYHQKHLKSIVNTRGASVVIGTTKFYGGWDNMLKNLIDGVENPCLMGWDY 4714
Query 5012 PKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGG 5071
PKCDRA+PNM+R++++++L KHTTCCS + RF+RL NE AQVL+E+V G Y+KPGG
Sbjct 4715 PKCDRALPNMIRMISAMILGSKHTTCCSSTDRFFRLCNELAQVLTEVVYSNGGFYLKPGG 4774
Query 5072 TSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDT 5131
T+SGDATTAYANSVFNI QAV+ANVN LLS D N + V+ LQ +LYEC YR+ VD
Sbjct 4775 TTSGDATTAYANSVFNIFQAVSANVNKLLSVDSNVCHNLEVKQLQRKLYECCYRSTIVDD 4834
Query 5132 DFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKC 5191
FV E+Y YLRKHFSMMILSDD VVC+N+ YAS G VA + FK+VLYYQNNVFMS +KC
Sbjct 4835 QFVVEYYGYLRKHFSMMILSDDGVVCYNNDYASLGYVADLNAFKAVLYYQNNVFMSASKC 4894
Query 5192 WTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERF 5251
W E D+ KGPHEFCSQHTM + + YLPYPDPSRIL AG FVDD+VKTD +++ER+
Sbjct 4895 WIEPDINKGPHEFCSQHTMQIVDKEGTYYLPYPDPSRILSAGVFVDDVVKTDAVVLLERY 4954
Query 5252 VSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPE 5311
VSLAIDAYPL+KH N EY VF++ L +++ L+ L +L+ +SV L D+T+++W+
Sbjct 4955 VSLAIDAYPLSKHENPEYKKVFYVLLDWVKHLYKTLNAGVLESFSVTLLEDSTAKFWDES 5014
Query 5312 FYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNP 5371
FY MY VLQ+ G CV+C SQT LRCG C+RRP LC KC YDHVI T+HK +L++ P
Sbjct 5015 FYANMYEKSAVLQSAGLCVVCGSQTVLRCGDCLRRPMLCTKCAYDHVIGTTHKFILAITP 5074
Query 5372 YVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFN 5431
YVC A C V DVT+LYLGG+SY+C HKP ++FPLC+ G VFGLYKN+ GS +V DFN
Sbjct 5075 YVCCASDCGVNDVTKLYLGGLSYWCHEHKPRLAFPLCSAGNVFGLYKNSATGSPDVEDFN 5134
Query 5432 AIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSW 5491
IAT DWT+ DY LAN + L+LFAAET+KA EE+ K SY AT+ EV+ +EL L W
Sbjct 5135 RIATSDWTDVSDYRLANDVKDSLRLFAAETIKAKEESVKSSYACATLHEVVGPKELLLKW 5194
Query 5492 EVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDY-GDAVVYRGTTTYKLNVGDYFV 5550
EVG+P+PPLNRN VFT Y +TKN+K QIGE+ FEK +Y DAV Y+ T T KL G FV
Sbjct 5195 EVGRPKPPLNRNSVFTCYHITKNTKFQIGEFVFEKAEYDNDAVTYKTTATTKLVPGMVFV 5254
Query 5551 LTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGT 5610
LTSH V PL APT+ QE Y I L+P NI + +SS V YQ +G QK +T+QGPPG+
Sbjct 5255 LTSHNVQPLRAPTIANQERYSTIHKLHPAFNIPEAYSSLVPYYQLIGKQKITTIQGPPGS 5314
Query 5611 GKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKF 5670
GKSH IGL LYYP ARIV+TACSHAAVD+LC KA DKCSRIIP RARVEC+D F
Sbjct 5315 GKSHCVIGLGLYYPGARIVFTACSHAAVDSLCVKASTAYSNDKCSRIIPQRARVECYDGF 5374
Query 5671 KVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLP 5730
K N+T QY+F TVNALPE ADIVV DE+SM TNYDLSV+N R+ +H VY+GDP QLP
Sbjct 5375 KSNNTSAQYLFSTVNALPECNADIVVVDEVSMCTNYDLSVINQRISYRHVVYVGDPQQLP 5434
Query 5731 APRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD 5790
APR ++++GTLEP+ +N V + M + PD+FL C RCPAEIV TVS +VY+N+
Sbjct 5435 APRVMISRGTLEPKDYNVVTQRMCALKPDVFLHKCYRCPAEIVRTVSEMVYENQFIPVHP 5494
Query 5791 KSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKIL 5850
S QCFK+F KG + D S+INR Q+ VVR FL +NP W KAVFISPYNSQN VAS++L
Sbjct 5495 DSKQCFKIFCKGNVQVDNGSSINRRQLDVVRMFLAKNPRWSKAVFISPYNSQNYVASRLL 5554
Query 5851 GLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQ 5910
GL QTVDSSQGSEYDYVI+ QT++TAH+ NVNRFNVAITRAK GILCIM DR L+D L+
Sbjct 5555 GLQIQTVDSSQGSEYDYVIYAQTSDTAHASNVNRFNVAITRAKKGILCIMCDRSLFDLLK 5614
Query 5911 FTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGI 5970
F L++ + LQA GLFKDCS+ L P+ A T +S+ FKT+ G+
Sbjct 5615 FFELKL-----SDLQANEGCGLFKDCSRGDDLLPPSHANTFMSLADNFKTDQYLAVQIGV 5669
Query 5971 PKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNL 6030
+ Y +IS MGF+ + + + +F TR+ A+R+VR W+GFDVEG H VGTN+
Sbjct 5670 NGPIKYEHVISFMGFRFDINIPNHHTLFCTRDFAMRNVRGWLGFDVEGAHVVGSNVGTNV 5729
Query 6031 PLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIK 6090
PLQLGFS GV+ V P G V T + V A+ PPG+QF HL+PL+ +G PW+VVR +
Sbjct 5730 PLQLGFSNGVDFVVRPEGCVVTESGDYIKPVRARAPPGEQFAHLLPLLKRGQPWDVVRKR 5789
Query 6091 IVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYA 6150
IVQM SD L NLSD ++FVLWA G ELT+M+YFVKIGP ++ C C + ATC+++A TY
Sbjct 5790 IVQMCSDYLANLSDILIFVLWAGGLELTTMRYFVKIGPSKS-CDCGKVATCYNSALHTYC 5848
Query 6151 CWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHEC 6210
C+ H++G DY+YNP+ ID+QQWG+ G+L NH +C VH N HVAS DAIMTRCLA+H+C
Sbjct 5849 CFKHALGCDYLYNPYCIDIQQWGYKGSLSLNHHEHCNVHRNEHVASGDAIMTRCLAIHDC 5908
Query 6211 FVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQAD 6270
FVK VDW+I YP IG+E IN + R VQ +++ L ++DIGNPK I+C D
Sbjct 5909 FVKNVDWSITYPFIGNEAVINKSGRIVQSHTMRSVLKLYNPKAIYDIGNPKGIRCA-VTD 5967
Query 6271 VEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRV 6330
+W +D P + +E Y Y TH DG+CLFWNCNVD YP S+VCRFDTR
Sbjct 5968 AKWFCFDKNPTNSNVKTLE---YDYITHGQ--FDGLCLFWNCNVDMYPEFSVVCRFDTRC 6022
Query 6331 LSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDY 6390
S LNL GC+GGSLYVN HAFHTPAFDK AF LK +PFF+Y D+ C+ ++ I+Y
Sbjct 6023 RSPLNLEGCNGGSLYVNNHAFHTPAFDKRAFAKLKPMPFFFYDDTECD----KLQDSINY 6078
Query 6391 VPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFT- 6449
VPL+++ CIT+CN+GGAVC H Y Y++AYN SAGF++WV FDTYNLW TF+
Sbjct 6079 VPLRASNCITKCNVGGAVCSKHCAMYHSYVNAYNTFTSAGFTIWVPTSFDTYNLWQTFSN 6138
Query 6450 RLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFEL 6509
LQ LEN+AFNV+ KG F G +GE+PV+++N+ V + VD +F NKT+LP NVAFEL
Sbjct 6139 NLQGLENIAFNVLKKGSFVGDEGELPVAVVNDKVLVRDGTVDTLVFTNKTSLPTNVAFEL 6198
Query 6510 WAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICA 6569
+AKR + P + IL NLGV + VIWDY+ + P T VC TD
Sbjct 6199 YAKRKVGLTPPITILRNLGVVCTSKCVIWDYEAERPLTTFTKDVCKYTDFE--------G 6250
Query 6570 PLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL-IGEAVKTQF 6628
+ FD + G ++ F +N VL++ +VK L + LNGV + E +
Sbjct 6251 DVCTLFDNSIVGSLERFSMTQNAVLMSLTAVKKLT-GIKLTYGYLNGVPVNTHEDKPFTW 6309
Query 6629 NYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIV 6688
Y + +G + P+ YFTQ R +F PRS ME DFL + M FI +Y LE Y FEH+V
Sbjct 6310 YIYTRKNGKFEDYPDGYFTQGRTTADFSPRSDMEKDFLSMDMGLFINKYGLEDYGFEHVV 6369
Query 6689 YGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPM-DSTVKNYFITDAQTGSSKCVCSVI 6747
YGD S + LGGLHLLI + ++++F+ DST+K+ +T A SSK VC+ +
Sbjct 6370 YGDVSKTTLGGLHLLISQVRLACMGVLKIDEFVSSNDSTLKSCTVTYADNPSSKMVCTYM 6429
Query 6748 DLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGV 6807
DLLLDDFV I+KS DLSVVSKV +V +D +MLWCKD ++TFYP+LQ+S+ W+ G
Sbjct 6430 DLLLDDFVSILKSLDLSVVSKVHEVMVDCKMWRWMLWCKDHKLQTFYPQLQASE-WKCGY 6488
Query 6808 AMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIH 6867
+MP++YK+QRM LE C+L NYG LP GIM NV KYTQLCQYLN+ T+ VP++MRV+H
Sbjct 6489 SMPSIYKIQRMCLEPCNLYNYGAGVKLPDGIMFNVVKYTQLCQYLNSTTMCVPHHMRVLH 6548
Query 6868 FGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIIS 6927
GAGSDKGVAPGTAVLR+WLP ++VD+D D+VSDAD ++ GDC+T++ ++K+DL+IS
Sbjct 6549 LGAGSDKGVAPGTAVLRRWLPLDAIIVDNDSVDYVSDADYSVTGDCSTLYLSDKFDLVIS 6608
Query 6928 DMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAW 6987
DMYD K K+ EN SKEGFF YI G I +KLALGG+VAIK+TE SWN LY+L+ F +
Sbjct 6609 DMYDGKIKSCDGENVSKEGFFPYINGVITEKLALGGTVAIKVTEFSWNKKLYELIQKFEY 6668
Query 6988 WTAFVTNVNASSSEAFLIGCNYLG--KPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDM 7045
WT F T+VN SSSEAFLIG +YLG IDG MHANYIFWRN+ + +S S+ D+
Sbjct 6669 WTMFCTSVNTSSSEAFLIGVHYLGDFASGAVIDGNTMHANYIFWRNSTIMTMSYNSVLDL 6728
Query 7046 SKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
SKF K + T V++LK+ I+D++L LL G+L++R N+ + S+ LVN
Sbjct 6729 SKFNCKHKATVVVNLKDSSISDVVLGLLKNGKLLVRNNDAICGFSNHLVN 6778
Score = 71.2 bits (173), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 58/173 (34%), Positives = 76/173 (44%), Gaps = 10/173 (6%)
Query 993 GSEDNQTTTIQTIVEVQPQLEMELTPVVQTIE---VNSFSGYLKLTDNVYIKNADIVEEA 1049
G + T+ TI L P V ++ V F Y NV D +
Sbjct 1255 GRHQIKYDTLNTICVKDVNWTAPLVPAVDSVVEPVVKPFYSY----KNVDFYQGDF-SDL 1309
Query 1050 KKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHN 1109
K+ VVNAAN L HGGG+A A++ T +Q S+DYI +GP+KVG +L
Sbjct 1310 VKLPCDFVVNAANEKLSHGGGIAKAIDVYTKGMLQKCSNDYIKAHGPIKVGRGVMLEA-- 1367
Query 1110 LAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSL 1162
L +VVGP K L+K+ F V L PL+S GIF SL
Sbjct 1368 LGLKVFNVVGPRKGKHAPELLVKAYKSVFANSGVALTPLISVGIFSVPLEESL 1420
Score = 48.9 bits (115), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 85/344 (25%), Positives = 138/344 (40%), Gaps = 38/344 (11%)
Query 1548 GEVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKI 1607
G V T D+++ + + V IKV T D ++ V+ + TYGQQ GP ++ VT
Sbjct 1616 GFVSTPDDVERFYANKSV-VIKV--TEDTRSVKAVKVESTATYGQQIGPCLVNDTVVTDN 1672
Query 1608 KPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQ--VNGLT 1665
KP + V+PN + ++ ++ D + G + L+HT + +P VNG
Sbjct 1673 KPVVADVVAK--VVPNAN------WDSHYGFDKA--GEF-HMLDHTG-FTFPSEVVNGRR 1720
Query 1666 SIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGEL 1725
IK DNNC++ L LQ +F LQ + G+ A F + G+
Sbjct 1721 VIKTTDNNCWVNVTCLQLQFARFRFKSAGLQAMWESYCTGDVAMFVHWLYWLTGVDKGQP 1780
Query 1726 GDVRETMSYLFQH---ANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKG 1782
D ++ L ++ A + +RV + C C ++ T V A + K G
Sbjct 1781 SDSENALNMLSKYIVPAGSVTIERVTHDGC-CCSKRVVTAPVVNASV---------LKLG 1830
Query 1783 VQ---IPCTCGKQATKYLVQQESPFVMMSAP---PAQYELKHGTFTCASEYTGNYQCGHY 1836
V+ P +V+ + V + P P+ LK ++T + GN GHY
Sbjct 1831 VEDGLCPHGLNYIGKVVVVKGTTIVVNVGKPVVAPSHLFLKGVSYTTFLD-NGNGVVGHY 1889
Query 1837 KHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPV 1880
+ T DG P+T+V E + PV
Sbjct 1890 T-VFDHGTGMVHDGDAFVPGDLNVSPVTNVVVSEQTAVVIKDPV 1932
>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus
229E OX=11137 GN=rep PE=1 SV=1
Length=6758
Score = 4258 bits (11044), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2277/4991 (46%), Positives = 3133/4991 (63%), Gaps = 237/4991 (5%)
Query 2172 FFTLLLQLCTFTRST----NSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLI 2227
FFT LL + T ++ + +I A P +S+ K+ L+AS LKS
Sbjct 1936 FFTWLLSMFTLCKTAVTTGDVKIMAKAPQRTGVVLKRSL-KYNLKASAAVLKSK------ 1988
Query 2228 NIIIWFLLLSVC-LGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSI 2286
W+LL L LIY+ ++ +L G ++C+ GY S N YC GS+
Sbjct 1989 ----WWLLAKFTKLLLLIYTLYSVVLLCVRFGPFNFCSETVNGYAKS-NFVKDDYCDGSL 2043
Query 2287 PCSVCLSGLDSLDTYPSLETI--QITISSFKWDLTAFGLVAEWFL---AYILFTRFFYVL 2341
C +CL G L + L+ + IT F ++ F ++ + Y+ ++V
Sbjct 2044 GCKMCLFGYQELSQFSHLDVVWKHITDPLFS-NMQPFIVMVLLLIFGDNYLRCFLLYFVA 2102
Query 2342 GLAAIMQLFFSY----FAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY 2397
+ + + +F Y + +HFI + ++ V + + + VR
Sbjct 2103 QMISTVGVFLGYKETNWFLHFIPFDVICDELLVTVIVIKVISFVR--------------- 2147
Query 2398 VHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDT 2457
HV+ GC + C+ C K R R TIVNGV+RSFYV ANGG FCK H + CV+CD+
Sbjct 2148 -HVLFGCENPDCIACSKSARLKRFPVNTIVNGVQRSFYVNANGGSKFCKKHRFFCVDCDS 2206
Query 2458 FCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLY---------FDKA 2508
+ GSTFI+ EV+R+L K + PT + ++D V +NG LY FD
Sbjct 2207 YGYGSTFITPEVSRELGNITKTNVQPTGPAYVMIDKVEFENGFYRLYSCETFWRYNFDIT 2266
Query 2509 GQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQP 2568
K + + LD+ N G+ NV + K+ASVY+SQL+C+P
Sbjct 2267 ESKYSCKEVFKNCNVLDDFIVFNNNGT---NV-----------TQVKNASVYFSQLLCRP 2312
Query 2569 ILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSL-D 2627
I L+D L+S + S + + AY++ ++F + L ++ AE + A +S+ D
Sbjct 2313 IKLVDSELLSTL--SVDFNGVLHKAYIDVLRNSFG---KDLNANMSLAECKRALGLSISD 2367
Query 2628 NVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNK-VENMTPR 2686
+ ++ IS A H+ D+ ++ S NN++ +Y K E ++
Sbjct 2368 HEFTSAISNA---------------------HRCDVLLSDLSFNNFVSSYAKPEEKLSAY 2406
Query 2687 DLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCAT 2746
DL C+ A+ +NA V ++W+ KDF SLS + RK I +K L F LT
Sbjct 2407 DLACCMRAGAKVVNANVLTKDQTPIVWHAKDFNSLSAEGRKYIVKTSKAKGLTFLLTINE 2466
Query 2747 TRQVVNVVTTKIALKGGKIVNN----WLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDF 2802
+ V + T I K G WL L + + F F ++S
Sbjct 2467 NQAVTQIPATSIVAKQGAGDAGHSLTWLWLLCGLVCLIQFYLCFFMPYFMYDIVS----- 2521
Query 2803 SSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTW-FSQRGGSYTNDKACPLIAAVITRE 2861
S E +K I+ G ++ + C N +F+ W +++ G + N ++CP++ V E
Sbjct 2522 SFEGYDFKYIENGQLKNFEAPLKCVRNVFENFEDWHYAKFGFTPLNKQSCPIVVGV--SE 2579
Query 2862 VGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICY------TPSKLIEYTDFATSACVL 2915
+ V G+P + G L F + +CY TP K C+
Sbjct 2580 IVNTVAGIPSNVYLV--GKTLIFTLQAAFGNAGVCYDIFGVTTPEK-----------CIF 2626
Query 2916 AAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEG-SVR 2974
+ CT + G V YCY+T ++EGS+ Y S++ + Y +G+ I+ P +G R
Sbjct 2627 TSACTRLEGLGGNNV-YCYNTALMEGSLPYSSIQANAYYKYDNGNFIKLPEVIAQGFGFR 2685
Query 2975 VVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPL 3034
V T ++YCR G C S AGVC +W +N+ R G CG NL+ N+ +
Sbjct 2686 TVRTIATKYCRVGECVESNAGVCFGFD-KWFVNDG--RVANGYVCGTGLWNLVFNILSMF 2742
Query 3035 IQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCL 3094
+S I+ + + +FRR FG+ S V + L++ +
Sbjct 2743 SSSFSVAAMSGQILLNCALGAFAIFCCFLVTKFRRMFGDLSVGVCTVVVAVLLNNVSYIV 2802
Query 3095 TPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFY 3154
T + Y+++Y + T L +++ +++ + P+W+ Y + + T
Sbjct 2803 TQNLVTMIA-YAILYFFATRSLR--YAWIWCAAYLIAYISFAPWWLCAWYFLAMLTG--- 2856
Query 3155 WFFSNYLKRRV---VFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
+ LK +V +F G F TFE AA TF+++ Y KL + + + Y A
Sbjct 2857 -LLPSLLKLKVSTNLFEGDKFVGTFESAAAGTFVIDMRSYEKLANSI--SPEKLKSYAAS 2913
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMA 3270
YN+YKY+SG + YR A +LAKA+ DFS +D+LY PP S S LQ+G RKMA
Sbjct 2914 YNRYKYYSGNANEADYRCACYAYLAKAMLDFSRDHNDILYTPPTVSYGST-LQAGLRKMA 2972
Query 3271 FPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLIRKSNHNF 3329
PSG VE C+V+V G T LNGLWL D+VYCPRHVI + + ++ ++E ++R HNF
Sbjct 2973 QPSGFVEKCVVRVCYGNTVLNGLWLGDIVYCPRHVIASNTTSAIDYDHEYSIMRL--HNF 3030
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G L V+G +M LK+KV N TP++ F ++ G+ F++LACY+G GV+
Sbjct 3031 SIISGTAFLGVVGATMHGVTLKIKVSQTNMHTPRHSFRTLKSGEGFNILACYDGCAQGVF 3090
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR N+TI+GSF+NG+CGS G+N+ V F YMH +EL +G H G+ +G YG F
Sbjct 3091 GVNMRTNWTIRGSFINGACGSPGYNLKNGEVEFVYMHQIELGSGSHVGSSFDGVMYGGFE 3150
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D+ Q + +TVNV+A+LYAA++NG W+L + +N A + + +
Sbjct 3151 DQPNLQVESANQMLTVNVVAFLYAAILNGCTWWLKGEKLFVEHYNEWAQANGFTAMNGE- 3209
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
D L+A+TG+ V + ++ ++L NG G+ ILG + L DEF+ +VV+Q GV Q
Sbjct 3210 -DAFSILAAKTGVCVERLLHAI-QVLNNGFGGKQILGYSSLNDEFSINEVVKQMFGVNLQ 3267
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYEN-AFL-PFAMGIIAMSAFAMM 3627
S K T + +++ V+ + + ++ N FL PF + ++A+S
Sbjct 3268 SG-----KTTSMFKSISLFAGFFVMFWAELFVYTTTIWVNPGFLTPFMILLVALSLCLTF 3322
Query 3628 FVKHKHAFLCLFLLPSLATVAYFNMVYMPASW---VMRIMTWLDMVDTSLSGFKLKDCVM 3684
VKHK FL +FLLPS+ A N +W V +++ + S+ ++ V
Sbjct 3323 VVKHKVLFLQVFLLPSIIVAAIQN-----CAWDYHVTKVLAEKFDYNVSVMQMDIQGFVN 3377
Query 3685 YASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNY 3744
+ + +L T R + L +++ ++Y Y +S+ +++ SN
Sbjct 3378 IFICLFVALLHTWRFAKERCTHWCTYLFSLIAVLYTALYSY---DYVSLLVMLLCAISNE 3434
Query 3745 SGVVTTVMFLAR-GIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
+ + + R G+ F+ VEY F + ++ ++L Y LG+ Y+GL +NR+
Sbjct 3435 WYIGAIIFRICRFGVAFLPVEYVSYF----DGVKTVLLFYMLLGFVSCMYYGLLYWINRF 3490
Query 3804 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMS 3863
+ TLGVYD+ VS EF+YM + GL P DA L+ KL+G+GG IKV+TVQSK++
Sbjct 3491 CKCTLGVYDFCVSPAEFKYMVANGLNAPNGPFDALFLSFKLMGIGGPRTIKVSTVQSKLT 3550
Query 3864 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3923
D+KCT+VVL+ +L + + S+SK WA CV++HN I L D A E +++LL+ LS
Sbjct 3551 DLKCTNVVLMGILSNMNIASNSKEWAYCVEMHNKINLCDDPETAQELLLALLAFFLSKHS 3610
Query 3924 AVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKS 3983
+ L + +N + LQ++AS F +PS+ A+ TA++ YE AVANG S ++K+LKK+
Sbjct 3611 DFGLGDLVDSYFENDSILQSVASSFVGMPSFVAYETARQEYENAVANGSSPQIIKQLKKA 3670
Query 3984 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4043
+NVAK+EFDR++++Q+K+ +MA+QA MYK+AR+ ++++KV SAM ++LF MLR+LD
Sbjct 3671 MNVAKAEFDRESSVQKKINRMAEQAAAAMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMS 3730
Query 4044 ALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY-KNTCDGTTFTYASALWEIQQVV 4102
+++ I+N AR+G VPL++IP T+AA+L+VV+PD++++ K DG YA +W +Q+V
Sbjct 3731 SVDTILNMARNGVVPLSVIPATSAARLVVVVPDHDSFVKMMVDGFVH-YAGVVWTLQEVK 3789
Query 4103 DADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4162
D D K V L +++ +N L WPLI+T R VKLQNNE+ P ++ +
Sbjct 3790 DNDGKNVHLKDVTKENQEILVWPLILTCERV---VKLQNNEIMPGKMKVKATKGEGDGGI 3846
Query 4163 CTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4222
++ NAL YN G F+ A ++ +K+ ++ G T+ ELEPPCRFV DTP G
Sbjct 3847 TSEGNAL--YNNEGGRAFMYAYVTTKPGMKYVKWEHDSGVVTV--ELEPPCRFVIDTPTG 3902
Query 4223 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKD 4282
P++KYLYF+K LNNL RG VLG + ATVRLQAG TE +NS +L+ C+FAVD A AY D
Sbjct 3903 PQIKYLYFVKNLNNLRRGAVLGYIGATVRLQAGKQTEFVSNSHLLTHCSFAVDPAAAYLD 3962
Query 4283 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4342
+ G +P+ NCVKML +G+GQAIT T ++N Q+++GGAS C+YCR H+ HP GF
Sbjct 3963 AVKQGAKPVGNCVKMLTNGSGSGQAITCTIDSNTTQDTYGGASVCIYCRAHVAHPTMDGF 4022
Query 4343 CDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNR 4402
C KGK+VQ+P NDP+ F L+NTVC VCG W +GC+CD+ +QS D S+LNR
Sbjct 4023 CQYKGKWVQVPIG-TNDPIRFCLENTVCKVCGCWLNHGCTCDR---TAIQSFD-NSYLNR 4077
Query 4403 VCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYF 4462
V G SAARL PC GT D RAFD+YN + K LK+NC RF+ D+DD +++
Sbjct 4078 VRGSSAARLEPC-NGTDIDYCVRAFDVYNKDASFIGKNLKSNCVRFKNVDKDD----AFY 4132
Query 4463 VVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYA 4522
+VKR S HE+++YNLLK C AVAKHDFF + + ++SRQ LTKYTM DL +A
Sbjct 4133 IVKRCIKSVMDHEQSMYNLLKGCNAVAKHDFFTWHEGRTIYGNVSRQDLTKYTMMDLCFA 4192
Query 4523 LRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTV 4582
LR+FDE +C+ KEILV CC DYF K+W+D +EN DI RVYA LG+ V A+LK V
Sbjct 4193 LRNFDEKDCEVFKEILVLTGCCSTDYFEMKNWFDPIENEDIHRVYAALGKVVANAMLKCV 4252
Query 4583 QFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRA 4642
FCD M G+VGVLTLDNQDLNGN+YDFGDF+ PG G+P SYYS +MP++ +T
Sbjct 4253 AFCDEMVLKGVVGVLTLDNQDLNGNFYDFGDFVLCPPGMGIPYCTSYYSYMMPVMGMTNC 4312
Query 4643 LTAESHVDTDL-TKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILH 4701
L +E + +D+ + + +DLLKYDFTE + LF++YFKYW Q YHP+CV+C D+ CILH
Sbjct 4313 LASECFMKSDIFGQDFKTFDLLKYDFTEHKEVLFNKYFKYWGQDYHPDCVDCHDEMCILH 4372
Query 4702 CANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFK 4761
C+NFN LF+T P T+FGPL RK+F+DGVP V + GYHF++LG+V N+DVN HS+RL+
Sbjct 4373 CSNFNTLFATTIPNTAFGPLCRKVFIDGVPVVATAGYHFKQLGLVWNKDVNTHSTRLTIT 4432
Query 4762 ELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFF 4821
ELL + DP + AS L+DKRT CFSVAAL+ + QTVKPG+FNK+FYDF S+GFF
Sbjct 4433 ELLQFVTDPTLIVASSPALVDKRTVCFSVAALSTGLTSQTVKPGHFNKEFYDFLRSQGFF 4492
Query 4822 KEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCIN 4881
EGS + LKHFFF Q G+AAI D+DYYRYN PTM DI Q +V +YFDCY+GGCI
Sbjct 4493 DEGSELTLKHFFFTQKGDAAIKDFDYYRYNRPTMLDIGQARVAYQVAARYFDCYEGGCIT 4552
Query 4882 ANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAIS 4941
+ +V+V NL+KSAG+P NK+GKA LYY+S+SYE+QDA+F+ TKRN++PT+TQ+NLKYAIS
Sbjct 4553 SREVVVTNLNKSAGWPLNKFGKAGLYYESISYEEQDAIFSLTKRNILPTMTQLNLKYAIS 4612
Query 4942 AKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDV 5001
K RARTV GVS+ +TMT RQFHQK LKSI ATR ATVVIGT+KFYGGW NMLK + +DV
Sbjct 4613 GKERARTVGGVSLLATMTTRQFHQKCLKSIVATRNATVVIGTTKFYGGWDNMLKNLMADV 4672
Query 5002 ENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMC 5061
++P LMGWDYPKCDRAMP+M+R++++++L KH TCC+ S +FYRL+NE AQVL+E+V
Sbjct 4673 DDPKLMGWDYPKCDRAMPSMIRMLSAMILGSKHVTCCTASDKFYRLSNELAQVLTEVVYS 4732
Query 5062 GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYE 5121
G Y KPGGT+SGDATTAYANSVFNI QAV++N+N +LS + + + V+ LQ +LY+
Sbjct 4733 NGGFYFKPGGTTSGDATTAYANSVFNIFQAVSSNINCVLSVNSSNCNNFNVKKLQRQLYD 4792
Query 5122 CLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQ 5181
YRN +VD FV++FY YL+KHFSMMILSDD+VVC+N TYA G +A I FK+ LYYQ
Sbjct 4793 NCYRNSNVDESFVDDFYGYLQKHFSMMILSDDSVVCYNKTYAGLGYIADISAFKATLYYQ 4852
Query 5182 NNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVK 5241
N VFMS AKCWTE DL+ GPHEFCSQHTM + + YLPYPDPSRI+ AG FVDDI K
Sbjct 4853 NGVFMSTAKCWTEEDLSIGPHEFCSQHTMQIVDENGKYYLPYPDPSRIISAGVFVDDITK 4912
Query 5242 TDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTN 5301
TD +++ER+VSLAIDAYPL+KHP EY VF+ L +++ L+ L +L+ +SV L +
Sbjct 4913 TDAVILLERYVSLAIDAYPLSKHPKPEYRKVFYALLDWVKHLNKTLNEGVLESFSVTLLD 4972
Query 5302 DNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVIST 5361
++ S++W+ FY +MY TVLQA G CV+C SQT LRCG C+RRP LC KC YDHV T
Sbjct 4973 EHESKFWDESFYASMYEKSTVLQAAGLCVVCGSQTVLRCGDCLRRPMLCTKCAYDHVFGT 5032
Query 5362 SHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTC 5421
HK +L++ PYVCN GC+V DVT+LYLGG++YYC HKP +SFPLC+ G VFGLYK++
Sbjct 5033 DHKFILAITPYVCNTSGCNVNDVTKLYLGGLNYYCVDHKPHLSFPLCSAGNVFGLYKSSA 5092
Query 5422 VGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREV 5481
+GS ++ FN ++T DW++ DY LAN E L+LFAAET+KA EE+ K SY AT++E+
Sbjct 5093 LGSMDIDVFNKLSTSDWSDIRDYKLANDAKESLRLFAAETVKAKEESVKSSYAYATLKEI 5152
Query 5482 LSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYG-DAVVYRGTTT 5540
+ +EL L WE GK +PPLNRN VFT +++TK+SK Q+GE+ FEK DYG D V Y+ T T
Sbjct 5153 VGPKELLLLWESGKAKPPLNRNSVFTCFQITKDSKFQVGEFVFEKVDYGSDTVTYKSTAT 5212
Query 5541 YKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQK 5600
KL G F+LTSH V PL APT+ QE Y I L+P+ N+SD +++ V YQ +G Q+
Sbjct 5213 TKLVPGMLFILTSHNVAPLRAPTMANQEKYSTIYKLHPSFNVSDAYANLVPYYQLIGKQR 5272
Query 5601 YSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPA 5660
+T+QGPPG+GKSH +IG+ +YYP ARIV+TACSHAAVD+LC KA+ +DKC+RIIPA
Sbjct 5273 ITTIQGPPGSGKSHCSIGIGVYYPGARIVFTACSHAAVDSLCAKAVTAYSVDKCTRIIPA 5332
Query 5661 RARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHY 5720
RARVEC+ FK N+ QYVF TVNALPE ADIVV DE+SM TNYDLSV+N R+ KH
Sbjct 5333 RARVECYSGFKPNNNSAQYVFSTVNALPEVNADIVVVDEVSMCTNYDLSVINQRISYKHI 5392
Query 5721 VYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALV 5780
VY+GDP QLPAPR L++KG +EP +N V + M IGPD+FL C RCPAEIV+TVS LV
Sbjct 5393 VYVGDPQQLPAPRVLISKGVMEPIDYNVVTQRMCAIGPDVFLHKCYRCPAEIVNTVSELV 5452
Query 5781 YDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYN 5840
Y+NK K+ S QCFK+F +G + D S+INR Q+ VV+ F+ +N W KAVFISPYN
Sbjct 5453 YENKFVPVKEASKQCFKIFERGSVQVDNGSSINRRQLDVVKRFIHKNSTWSKAVFISPYN 5512
Query 5841 SQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIM 5900
SQN VA+++LGL TQTVDS+QGSEYDYVIF QT++TAH+CN NRFNVAITRAK GI CIM
Sbjct 5513 SQNYVAARLLGLQTQTVDSAQGSEYDYVIFAQTSDTAHACNANRFNVAITRAKKGIFCIM 5572
Query 5901 SDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT 5960
SDR L+D L+F + + LQ+E+ GLFKDC++ L P+ A T+LS+ +FKT
Sbjct 5573 SDRTLFDALKFFEITM-----TDLQSESSCGLFKDCARNPIDLPPSHATTYLSLSDRFKT 5627
Query 5961 EG-LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGC 6019
G L V I G TY +IS MGF+ + + G ++F TR+ A+RHVR W+G DVEG
Sbjct 5628 SGDLAVQI-GNNNVCTYEHVISYMGFRFDVSMPGSHSLFCTRDFAMRHVRGWLGMDVEGA 5686
Query 6020 HATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMY 6079
H T + VGTN+PLQ+GFS GV+ VA P G V T + V A+ PPG+QF H++PL+
Sbjct 5687 HVTGDNVGTNVPLQVGFSNGVDFVAQPEGCVLTNTGSVVKPVRARAPPGEQFTHIVPLLR 5746
Query 6080 KGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRA 6139
KG PW+V+R +IVQM++D L SD +VFVLWA G ELT+M+YFVKIG + C C A
Sbjct 5747 KGQPWSVLRKRIVQMIADFLAGSSDVLVFVLWAGGLELTTMRYFVKIGAVKH-CQCGTVA 5805
Query 6140 TCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDA 6199
TC+++ S+ Y C+ H++G DYVYNP++ID+QQWG+ G+L +NH C VH N HVAS DA
Sbjct 5806 TCYNSVSNDYCCFKHALGCDYVYNPYVIDIQQWGYVGSLSTNHHAICNVHRNEHVASGDA 5865
Query 6200 IMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGN 6259
IMTRCLAV++CFVK VDW+I YP+I +E IN R VQ +++AA+ +HDIGN
Sbjct 5866 IMTRCLAVYDCFVKNVDWSITYPMIANENAINKGGRTVQSHIMRAAIKLYNPKAIHDIGN 5925
Query 6260 PKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPA 6319
PK I+C D +W YD P + +E Y Y TH DG+CLFWNCNVD YP
Sbjct 5926 PKGIRCAV-TDAKWYCYDKNPINSNVKTLE---YDYMTHGQ--MDGLCLFWNCNVDMYPE 5979
Query 6320 NSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCES 6379
SIVCRFDTR S LNL G +GGSLYVN HAFHTPA+DK A LK PFFYY D CE
Sbjct 5980 FSIVCRFDTRTRSTLNLEGVNGGSLYVNNHAFHTPAYDKRAMAKLKPAPFFYYDDGSCE- 6038
Query 6380 HGKQVVSD-IDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQ 6438
VV D ++YVPL++ CIT+CN+GGAVC HAN YR Y+++YN+ AGF++WV
Sbjct 6039 ----VVHDQVNYVPLRATNCITKCNIGGAVCSKHANLYRAYVESYNIFTQAGFNIWVPTT 6094
Query 6439 FDTYNLWNTFTR--LQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFE 6496
FD YNLW TFT LQ LEN+AFNVVNKG F G GE+PV+I + V+ + D +F
Sbjct 6095 FDCYNLWQTFTEVNLQGLENIAFNVVNKGSFVGADGELPVAISGDKVFVRDGNTDNLVFV 6154
Query 6497 NKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSM 6556
NKT+LP N+AFEL+AKR + P + IL NLGV V+WDY+ + P T VC
Sbjct 6155 NKTSLPTNIAFELFAKRKVGLTPPLSILKNLGVVATYKFVLWDYEAERPLTSFTKSVCGY 6214
Query 6557 TDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVK---GLQPSVGPKQAS 6613
TD A E +C +D + G + F + N VL + +VK P++
Sbjct 6215 TDFA----EDVCTC----YDNSIQGSYERFTLSTNAVLFSATAVKTGGKSLPAIKLNFGM 6266
Query 6614 LNGVTLI------GEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLE 6667
LNG + G + Y + DG + ++TQ RNLQ+F PRS ME DFL
Sbjct 6267 LNGNAIATVKSEDGNIKNINWFVYVRKDGKPVDHYDGFYTQGRNLQDFLPRSTMEEDFLN 6326
Query 6668 LAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPM-DST 6726
+ + FI++Y LE + FEH+VYGD S + LGGLHLLI + K + E+F+ D T
Sbjct 6327 MDIGVFIQKYGLEDFNFEHVVYGDVSKTTLGGLHLLISQVRLSKMGILKAEEFVAASDIT 6386
Query 6727 VKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCK 6786
+K +T SSK VC+ +DLLLDDFV ++KS DL+VVSKV +V ID +MLWCK
Sbjct 6387 LKCCTVTYLNDPSSKTVCTYMDLLLDDFVSVLKSLDLTVVSKVHEVIIDNKPWRWMLWCK 6446
Query 6787 DGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYT 6846
D V TFYP+LQS++ W+ G +MP +YK QRM LE C+L NYG LP GIM NV KYT
Sbjct 6447 DNAVATFYPQLQSAE-WKCGYSMPGIYKTQRMCLEPCNLYNYGAGLKLPSGIMFNVVKYT 6505
Query 6847 QLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDAD 6906
QLCQY N+ TL VP+NMRV+H GAGSD GVAPGTAVL++WLP ++VD+D+ D+VSDAD
Sbjct 6506 QLCQYFNSTTLCVPHNMRVLHLGAGSDYGVAPGTAVLKRWLPHDAIVVDNDVVDYVSDAD 6565
Query 6907 STLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVA 6966
++ GDCATV+ +K+DL+ISDMYD +TK + EN SKEGFFTYI GFI +KLA+GGS+A
Sbjct 6566 FSVTGDCATVYLEDKFDLLISDMYDGRTKAIDGENVSKEGFFTYINGFICEKLAIGGSIA 6625
Query 6967 IKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQ--IDGYVMHA 7024
IK+TE+SWN LY+L+ F++WT F T+VN SSSEAF++G NYLG + IDG ++HA
Sbjct 6626 IKVTEYSWNKKLYELVQRFSFWTMFCTSVNTSSSEAFVVGINYLGDFAQGPFIDGNIIHA 6685
Query 7025 NYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENN 7084
NY+FWRN+ + LS S+ D+SKF K + T V+ LK+ IN+M+LSL+ G+L++R N
Sbjct 6686 NYVFWRNSTVMSLSYNSVLDLSKFNCKHKATVVVQLKDSDINEMVLSLVRSGKLLVRGNG 6745
Query 7085 RVVISSDVLVN 7095
+ + S+ LV+
Sbjct 6746 KCLSFSNHLVS 6756
Score = 76.3 bits (186), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 71/245 (29%), Positives = 110/245 (45%), Gaps = 16/245 (7%)
Query 991 QDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYL---KLT-----DNVYIKN 1042
Q + D T + ++E+ +TP+ T++ ++ KL DNV
Sbjct 1226 QPWTNDALNTICIKDADYNAKVEISVTPIKNTVDTTPKEEFVVKEKLNAFLVHDNVAFYQ 1285
Query 1043 ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGS 1102
D+ V +VNAAN L HGGG+A AL+ T +Q S ++I G +KVG
Sbjct 1286 GDVDTVVNGVDFDFIVNAANENLAHGGGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTG 1345
Query 1103 CVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSL 1162
++ +L +VVGP K E L+K+ N+ L P+LS GIFG SL
Sbjct 1346 VMVECDSL--RIFNVVGPRKGKHERDLLIKAYNTINNEQGTPLTPILSCGIFGIKLETSL 1403
Query 1163 RVCVDTVRTN-VYLAVFDKNLYDKL---VSSFLEMKSEKQ--VEQKIAEIPKEEVKPFIT 1216
V +D T V + V+ K+ VS + ++ +Q +E K + K KP+
Sbjct 1404 EVLLDVCNTKEVKVFVYTDTEVCKVKDFVSGLVNVQKVEQPKIEPKPVSVIKVAPKPYRV 1463
Query 1217 ESKPS 1221
+ K S
Sbjct 1464 DGKFS 1468
Score = 55.8 bits (133), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 74/339 (22%), Positives = 137/339 (40%), Gaps = 30/339 (9%)
Query 1560 LSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFY 1619
L E + I + T D +N+H V ++ QQ G D++ P + + +
Sbjct 1595 LKAAEAKVITIKVTEDGVNVHDVTVTTDKSFEQQVGVIADKDKDLSGAVPSDLNTSELL- 1653
Query 1620 VLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTK-KWKYPQVNGLTSIKWADNNCYLAT 1678
+ V+ E+Y D + ++H+ ++ VNG+ +K +DNNC++
Sbjct 1654 ----TKAIDVDWVEFYGFKD----AVTFATVDHSAFAYESAVVNGIRVLKTSDNNCWVNA 1705
Query 1679 ALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQH 1738
+ LQ + F L A+ + G+ F A + G+ GD +T++ L ++
Sbjct 1706 VCIALQYSKPHFISQGLDAAWNKFVLGDVEIFVAFVYYVARLMKGDKGDAEDTLTKLSKY 1765
Query 1739 -ANLDSCKRVLNVVCKTCGQQ-QTTLKGVEAVMYMGTLSYEQFKKGVQIP-CTCGKQATK 1795
AN + C C + + ++ + + + ++ + GVQ+ C G +
Sbjct 1766 LANEAQVQLEHYSSCVECDAKFKNSVASINSAIVCASVK----RDGVQVGYCVHGIKYYS 1821
Query 1796 YLVQQESPFVMMSA----PPAQYELKHGTFTCASEYTGNYQCGHYK-HITSKETLYCIDG 1850
+ +++S P AQ L G A ++G GHY + T+K+++Y DG
Sbjct 1822 RVRSVRGRAIIVSVEQLEPCAQSRLLSGVAYTA--FSGPVDKGHYTVYDTAKKSMY--DG 1877
Query 1851 ALLTKSSEYKGPITDVF----YKENSYTTTIKPVTYKLD 1885
K +T V Y T KPV +LD
Sbjct 1878 DRFVKHDLSLLSVTSVVMVGGYVAPVNTVKPKPVINQLD 1916
Score = 50.1 bits (118), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 62/267 (23%), Positives = 110/267 (41%), Gaps = 18/267 (7%)
Query 1658 YPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAY 1717
+ ++NGL +K DNNC++ + +L +Q + A+Q + R + C
Sbjct 1038 FEELNGLKILKQLDNNCWVNSVMLQIQLTGILDGDYAMQ-FFKMGRVAKMIERC-YTAEQ 1095
Query 1718 CNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYE 1777
C + G +GDV M L + +L + V++ C +C + G AV++ T + +
Sbjct 1096 CIR--GAMGDVGLCMYRLLK--DLHTGFMVMDYKC-SCTSGRLEESG--AVLFC-TPTKK 1147
Query 1778 QFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYK 1837
F G + C + T +Q FV P C+S + G CGHY+
Sbjct 1148 AFPYGTCLNCNAPRMCTIRQLQGTIIFVQQKPEPVNPVSFVVKPVCSSIFRGAVSCGHYQ 1207
Query 1838 HITSKETLYCIDGALLTKSSEYKG-PITDVFYKENSYTT----TIKPVTYKLDGVVCTE- 1891
+ L C+DG + K + + + K+ Y ++ P+ +D E
Sbjct 1208 TNIYSQNL-CVDGFGVNKIQPWTNDALNTICIKDADYNAKVEISVTPIKNTVDTTPKEEF 1266
Query 1892 -IDPKLDNYYKKDNSYFTEQPIDLVPN 1917
+ KL+ + DN F + +D V N
Sbjct 1267 VVKEKLNAFLVHDNVAFYQGDVDTVVN 1293
Score = 38.1 bits (87), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 62/267 (23%), Positives = 106/267 (40%), Gaps = 27/267 (10%)
Query 662 GQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCV 721
G + TCAK K + + N FL ++ IGG K + ++ + +
Sbjct 749 GLLGTCAKRFKRWLGILLEAYNAFLDTVVSTVKIGGLTFKTYAFDKPYIVIRDIVCKVEN 808
Query 722 KSREETGLLMPLKAP-KEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
K+ E L P K E +P T D++ +E +E VE G
Sbjct 809 KTEAEWIELFPHNDRIKSFSTFESAYMPIADPTHF------DIEEVELLDAEFVEPGCGG 862
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDT-VIEVQGYKSV 839
I+ + + KD Y + N++ FT G KV+F DD V +++ V
Sbjct 863 ILAVIDEHVFYK-KDGVYYPSNGTNILPV--AFTKAAGG--KVSFSDDVEVKDIEPVYRV 917
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
+ FE + D+ L + C +G ++ D+ KT+Q + L +
Sbjct 918 KLCFEFE---DEKLVDVCEK---AIGKKIKHEG--DWDSFCKTIQ------SALSVVSCY 963
Query 900 WSMATYYLFDESGEFKLASHMYCSFYP 926
++ TYY++DE G L+ + S +P
Sbjct 964 VNLPTYYIYDEEGGNDLSLPVMISEWP 990
>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=rep PE=1 SV=1
Length=6684
Score = 4213 bits (10927), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2240/4896 (46%), Positives = 3057/4896 (62%), Gaps = 197/4896 (4%)
Query 2263 CTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWD----L 2318
C G + Y NS+ + A C SI C CL+ D L + L+ S W+ L
Sbjct 1921 CNGAVQAYKNSSFIKSAV-CGNSILCKACLASYDELADFQHLQVTWDFKSDPLWNRLVQL 1979
Query 2319 TAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPIS 2378
+ F +A + Y+ R F + ++ + L+ SYF ++ SW + ++V IS
Sbjct 1980 SYFAFLAVFGNNYV---RCFLMYFVSQYLNLWLSYFG--YVEYSWFL----HVVNFESIS 2030
Query 2379 AMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYA 2438
A + + K H+V C++ +C C + R TR+ +VNG ++ YV+A
Sbjct 2031 AEFVIVVIVVKAVLALK---HIVFACSNPSCKTCSRTARQTRIPIQVVVNGSMKTVYVHA 2087
Query 2439 NGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKN 2498
NG FCK HN+ C NCD++ +TFI DE+ RDLS K+ + TD+S V V +
Sbjct 2088 NGTGKFCKKHNFYCKNCDSYGFENTFICDEIVRDLSNSVKQTVYATDRSHQEVTKVECSD 2147
Query 2499 GSIHLY---------FDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKC 2549
G Y +D +K + L + LD+ + GS NV
Sbjct 2148 GFYRFYVGDEFTSYDYDVKHKKYSSQEVLKSMLLLDDFIVYSPSGSALANV--------- 2198
Query 2550 EESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKL 2609
++A VY+SQL+ +PI +++ L+ D+ S + +F+A N ++FNV + +
Sbjct 2199 -----RNACVYFSQLIGKPIKIVNSDLLEDL--SVDFKGALFNAKKNVIKNSFNVDVSEC 2251
Query 2610 KTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDS 2669
K L E + +L+ STF A +H+ I +T S
Sbjct 2252 KNL-----DECYRACNLNVSFSTFEMAVNN------------------AHRFGILITDRS 2288
Query 2670 CNNYMLTYNK--VENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRK 2727
NN+ + K ++ D+G C+ A+ +NA+V +++W +DF +LS +K
Sbjct 2289 FNNFWPSKVKPGSSGVSAMDIGKCMTSDAKIVNAKVLTQRGKSVVWLSQDFAALSSTAQK 2348
Query 2728 QIRSAAKKNNLPFKLTCATTRQVVNV----VTTKIALKGGK---IVNNWLKQLIKVTLVF 2780
+ + + F LT ++ T ++ K G V LKQ++ + VF
Sbjct 2349 VLVKTFVEEGVNFSLTFNAVGSDDDLPYERFTESVSPKSGSGFFDVITQLKQIVILVFVF 2408
Query 2781 LFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQ 2840
+F+ L + V ++ S+E Y I G+ + T +C N + F WF
Sbjct 2409 IFICG---LCSVYSVATQSYIESAEGYDYMVIKNGIVQPFDDTISCVHNTYKGFGDWFKA 2465
Query 2841 RGGSY-TNDKACPLIAA-VITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYT 2898
+ G T K+CP++ V E +P +P + + G L F V N+CY
Sbjct 2466 KYGFIPTFGKSCPIVVGTVFDLENMRPIPDVPAYV--SIVGRSLVFAINAAFGVTNMCYD 2523
Query 2899 PSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMD 2958
+ D CV CT G V YC ++EG+ Y L PD Y
Sbjct 2524 HTGNAVSKDSYFDTCVFNTACTTLTGLGGTIV-YCAKQGLVEGAKLYSDLMPDYYYEHAS 2582
Query 2959 GSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVF 3018
G++++ P +R V T + YCR G C S+AG C +V +N++ G
Sbjct 2583 GNMVKLPAIIRGLGLRFVKTQATTYCRVGECIDSKAGFCFGGDNWFVYDNEFGN---GYI 2639
Query 3019 CGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVV 3078
CG + N+F + + S +++ I+A + + Y ++F++ FG+
Sbjct 2640 CGNSVLGFFKNVFKLFNSNMSVVATSGAMLVNIIIACLAIAMCYGVLKFKKIFGDC---- 2695
Query 3079 AFNTLLFLMSFTVLCLTPVYSFLPG--VYSVIYLYLTFYLTNDVSF--LAHIQWMVMFTP 3134
T L +M L + V F+ + +IY + +++T +++ + +++ +
Sbjct 2696 ---TFLIVMIIVTLVVNNVSYFVTQNTFFMIIYAIVYYFITRKLAYPGILDAGFIIAYIN 2752
Query 3135 LVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFNGVSF-STFEEAALCTFLLNKEMY 3190
+ P+++ AYI+ Y + K +V +F G F FE AA+ TF+++ Y
Sbjct 2753 MAPWYVITAYILVF----LYDSLPSLFKLKVSTNLFEGDKFVGNFESAAMGTFVIDMRSY 2808
Query 3191 LKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLY 3250
+ + + + Y +NKYKY++G+M YR A HL KAL D+S + +D+LY
Sbjct 2809 ETIVNST--SIARIKSYANSFNKYKYYTGSMGEADYRMACYAHLGKALMDYSVNRTDMLY 2866
Query 3251 QPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSE 3310
PP S+ S LQSG RKMA PSG VE C+V+V+ G LNGLWL D V CPRHVI S+
Sbjct 2867 TPPTVSVNST-LQSGLRKMAQPSGLVEPCIVRVSYGNNVLNGLWLGDEVICPRHVI-ASD 2924
Query 3311 DMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQ 3370
NYE+ + HNF V NV L V+ + L LKV+ NP TP++KF I+
Sbjct 2925 TTRVINYENEMSSVRLHNFSVSKNNVFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIK 2984
Query 3371 PGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMEL 3430
G++F++LACY G P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL
Sbjct 2985 AGESFNILACYEGCPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLEL 3044
Query 3431 PTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTL 3490
G H G++ EG YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + +L
Sbjct 3045 GNGSHVGSNFEGEMYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSL 3104
Query 3491 NDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALL 3550
+N A ++ L+ D L+A+TG +V + S+ L G GRTIL L
Sbjct 3105 ESYNTWAKTNSFTELSS--TDAFSMLAAKTGQSVEKLLDSIVRL-NKGFGGRTILSYGSL 3161
Query 3551 EDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLY--- 3607
DEFTP +V+RQ GV Q+ ++ I+T++ +L + L FF+Y
Sbjct 3162 CDEFTPTEVIRQMYGVNLQAGKVKS-------FFYPIMTAMTILFA---FWLEFFMYTPF 3211
Query 3608 ---ENAFLPFAMGIIAM-SAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRI 3663
F+ + + + S + +KHK F F+LPS+ V N+ + S+ +
Sbjct 3212 TWINPTFVSIVLAVTTLISTVFVSGIKHKMLFFMSFVLPSVILVTAHNL-FWDFSYYESL 3270
Query 3664 MTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYY 3723
+ ++ +T ++ ++ ++ + + R + + +L + V
Sbjct 3271 QSIVENTNTMFLPVDMQGVMLTVFCFIVFVTYSVRFFTCKQSWFSLAVTTILVIFNMVKI 3330
Query 3724 GNALDQA----------ISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
D+ ++M +I+S+T+ VV +A IV +CV P F++
Sbjct 3331 FGTSDEPWTENQIAFCFVNMLTMIVSLTTKDWMVVIASYRIAYYIV-VCV--MPSAFVSD 3387
Query 3774 -NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK 3832
++CI +VY GY CY+G+ +NR+ +T GVY + VS E +YM + L PK
Sbjct 3388 FGFMKCISIVYMACGYLFCCYYGILYWVNRFTCMTCGVYQFTVSAAELKYMTANNLSAPK 3447
Query 3833 NSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV 3892
N+ DA L+ KL+GVGGK IK++TVQSK++++KCT+VVLL +L ++ VES+SK W CV
Sbjct 3448 NAYDAMILSAKLIGVGGKRNIKISTVQSKLTEMKCTNVVLLGLLSKMHVESNSKEWNYCV 3507
Query 3893 QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP 3952
LHN+I L D EK+++L++ LS D+++L E +N LQ++AS +++LP
Sbjct 3508 GLHNEINLCDDPEIVLEKLLALIAFFLSKHNTCDLSELIESYFENTTILQSVASAYAALP 3567
Query 3953 SYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQM 4012
S+ A A+ E+A N S +LK+L K+ N+AKS+F+R+A++Q+KL+KMA+QA M
Sbjct 3568 SWIALEKARADLEEAKKNDVSPQILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAAASM 3627
Query 4013 YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV 4072
YK+AR+ D+++K+ SAM ++LF ML+KLD ++N II+ AR+G +PL+IIP +A +L+V
Sbjct 3628 YKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATRLVV 3687
Query 4073 VIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALR 4132
+ P + YA A+W I +V DA+ V L E++ N NL WPL +T R
Sbjct 3688 ITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAANELNLTWPLSITCER 3747
Query 4133 ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLK 4192
KLQNNE+ P L++ + A T + A + G F+ A ++ +LK
Sbjct 3748 T---TKLQNNEIMPGKLKERAVRASATLDGEAFGSGKALMASESGKSFMYAFIASDNNLK 3804
Query 4193 WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRL 4252
+ ++ ++ I ELE P RF D GP+VKYLYF+K LN L RG VLG + ATVRL
Sbjct 3805 YVKWESNNDI--IPIELEAPLRFYVDGANGPEVKYLYFVKNLNTLRRGAVLGYIGATVRL 3862
Query 4253 QAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP 4312
QAG TE P+NS++L+ CAF+ D AKAY D + G QP+ NCVKML G G A+T
Sbjct 3863 QAGKPTEHPSNSSLLTLCAFSPDPAKAYVDAVKRGMQPVNNCVKMLSNGAGNGMAVTNGV 3922
Query 4313 EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTV 4372
EAN Q+S+GGAS C+YCRCH++HP G C KGK+VQIPT DP+ F ++N VC V
Sbjct 3923 EANTQQDSYGGASVCIYCRCHVEHPAIDGLCRYKGKFVQIPTG-TQDPIRFCIENEVCVV 3981
Query 4373 CGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYND 4432
CG W GC CD R M QS+LNRV G SAARL PC GT D V RAFDIYN
Sbjct 3982 CGCWLNNGCMCD--RTSMQSFTVDQSYLNRVRGSSAARLEPC-NGTDPDHVSRAFDIYNK 4038
Query 4433 KVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHD 4492
VA KFLKTNC RF+ D+ D +Y++VKR T + HE+ YN LKD AVA+HD
Sbjct 4039 DVACIGKFLKTNCSRFRNLDKHD----AYYIVKRCTKTVMDHEQVCYNDLKDSGAVAEHD 4094
Query 4493 FFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKK 4552
FF ++ +++R+ LTKYTM DL YA+R+FDE NC+ LKEILVT C +++F K
Sbjct 4095 FFTYKEGRCEFGNVARRNLTKYTMMDLCYAIRNFDEKNCEVLKEILVTVGACTEEFFENK 4154
Query 4553 DWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFG 4612
DW+D VEN I VYA LG V A+LK V FCDA+ G +GV+TLDNQDLNGN+YDFG
Sbjct 4155 DWFDPVENEAIHEVYAKLGPIVANAMLKCVAFCDAIVEKGYIGVITLDNQDLNGNFYDFG 4214
Query 4613 DFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDL-TKPYIKWDLLKYDFTEER 4671
DF++T PG G V SYYS +MP++ +T L +E+ V +D+ Y ++DLL YDFTE +
Sbjct 4215 DFVKTAPGFGCACVTSYYSYMMPLMGMTSCLESENFVKSDIYGSDYKQYDLLAYDFTEHK 4274
Query 4672 LKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVP 4731
LF +YFKYWD+TYHPNC +C D CI+HCANFN LFS P T+FGPLVRK+ +DGVP
Sbjct 4275 EYLFQKYFKYWDRTYHPNCSDCTSDECIIHCANFNTLFSMTIPMTAFGPLVRKVHIDGVP 4334
Query 4732 FVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVA 4791
VV+ GYHF++LG+V N DV L + +LS +LL + DP + AS LLD+RT CFS+A
Sbjct 4335 VVVTAGYHFKQLGIVWNLDVKLDTMKLSMTDLLRFVTDPTLLVASSPALLDQRTVCFSIA 4394
Query 4792 ALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYN 4851
AL+ + +QTVKPG+FNKDFYDF +GFF+EGS + LKHFFFAQ G AA++D++YYRYN
Sbjct 4395 ALSTGITYQTVKPGHFNKDFYDFITERGFFEEGSELTLKHFFFAQGGEAAMTDFNYYRYN 4454
Query 4852 LPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSM 4911
T+ DI Q FV ++V KYF+CYDGGCINA +V+V N DKSAG+P NK+GKARLYY+++
Sbjct 4455 RVTVLDICQAQFVYKIVGKYFECYDGGCINAREVVVTNYDKSAGYPLNKFGKARLYYETL 4514
Query 4912 SYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSI 4971
SYE+QDALFA TKRNV+PT+TQMNLKYAIS K RARTV GVS+ STMT RQ+HQK LKSI
Sbjct 4515 SYEEQDALFALTKRNVLPTMTQMNLKYAISGKARARTVGGVSLLSTMTTRQYHQKHLKSI 4574
Query 4972 AATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLA 5031
AATR ATVVIG++KFYGGW NMLK + DV+N LMGWDYPKCDRA+PNM+R+ ++++L
Sbjct 4575 AATRNATVVIGSTKFYGGWDNMLKNLMRDVDNGCLMGWDYPKCDRALPNMIRMASAMILG 4634
Query 5032 RKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQA 5091
KH CC+ + RFYRL+NE AQVL+E+V C G Y KPGGT+SGD TTAYANS FNI QA
Sbjct 4635 SKHVGCCTHNDRFYRLSNELAQVLTEVVHCTGGFYFKPGGTTSGDGTTAYANSAFNIFQA 4694
Query 5092 VTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILS 5151
V+ANVN LL D N + V+++Q ++Y+ YR+ +D +FV E+++YLRKHFSMMILS
Sbjct 4695 VSANVNKLLGVDSNACNNVTVKSIQRKIYDNCYRSSSIDEEFVVEYFSYLRKHFSMMILS 4754
Query 5152 DDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTML 5211
DD VVC+N YA G VA I FK+ LYYQNNVFMS +KCW E DL+ GPHEFCSQHT+
Sbjct 4755 DDGVVCYNKDYADLGYVADINAFKATLYYQNNVFMSTSKCWVEPDLSVGPHEFCSQHTLQ 4814
Query 5212 VKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYAD 5271
+ D YLPYPDPSRIL AG FVDDIVKTD +M+ER+VSLAIDAYPLTKHP Y
Sbjct 4815 IVGPDGDYYLPYPDPSRILSAGVFVDDIVKTDNVIMLERYVSLAIDAYPLTKHPKPAYQK 4874
Query 5272 VFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVL 5331
VF+ L +++ L L +LD +SV + + ++W EFY ++Y TVLQA G CV+
Sbjct 4875 VFYTLLDWVKHLQKNLNAGVLDSFSVTMLEEGQDKFWSEEFYASLYEKSTVLQAAGMCVV 4934
Query 5332 CNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGG 5391
C SQT LRCG C+RRP LC KC YDHV+ T HK ++S+ PYVC+ GC+V DVT+L+LGG
Sbjct 4935 CGSQTVLRCGDCLRRPLLCTKCAYDHVMGTKHKFIMSITPYVCSFNGCNVNDVTKLFLGG 4994
Query 5392 MSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCT 5451
+SYYC +HKP +SFPLCANG VFGLYK++ VGS+ V DFN +A DWTN DY LAN
Sbjct 4995 LSYYCMNHKPQLSFPLCANGNVFGLYKSSAVGSEAVEDFNKLAVSDWTNVEDYKLANNVK 5054
Query 5452 ERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRV 5511
E LK+FAAET+KA EE+ K Y A ++EV+ +E+ L WE K +PPLNRN VFT +++
Sbjct 5055 ESLKIFAAETVKAKEESVKSEYAYAVLKEVIGPKEIVLQWEASKTKPPLNRNSVFTCFQI 5114
Query 5512 TKNSKVQIGEYTFEKGDYG-DAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY 5570
+K++K+Q+GE+ FE+ +YG D+V Y+ T+TYKL G FVLTSH V PL AP LV QE Y
Sbjct 5115 SKDTKIQLGEFVFEQSEYGSDSVYYKSTSTYKLTPGMIFVLTSHNVSPLKAPILVNQEKY 5174
Query 5571 VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVY 5630
I+ LYP NI++ +++ V YQ +G QK++T+QGPPG+GKSH IGL LYYP ARIVY
Sbjct 5175 NTISKLYPVFNIAEAYNTLVPYYQMIGKQKFTTIQGPPGSGKSHCVIGLGLYYPQARIVY 5234
Query 5631 TACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPET 5690
TACSHAAVDALCEKA K +D+CSRIIP R RV+C+ FK N+T QY+FCTVNALPE
Sbjct 5235 TACSHAAVDALCEKAAKNFNVDRCSRIIPQRIRVDCYTGFKPNNTNAQYLFCTVNALPEA 5294
Query 5691 TADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC 5750
+ DIVV DE+SM TNYDLSV+N+RL KH VY+GDP QLPAPRTL+ KG L+P+ +N V
Sbjct 5295 SCDIVVVDEVSMCTNYDLSVINSRLSYKHIVYVGDPQQLPAPRTLINKGVLQPQDYNVVT 5354
Query 5751 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSS 5810
+ M T+GPD+FL C RCPAEIV TVSALVY+NK +S QCFKMF KG + + +S
Sbjct 5355 KRMCTLGPDVFLHKCYRCPAEIVKTVSALVYENKFVPVNPESKQCFKMFVKGQVQIESNS 5414
Query 5811 AINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIF 5870
+IN Q+ VV+ FL NP WRKAVFISPYNSQN VA ++LGL TQTVDS+QGSEYDYVI+
Sbjct 5415 SINNKQLEVVKAFLAHNPKWRKAVFISPYNSQNYVARRLLGLQTQTVDSAQGSEYDYVIY 5474
Query 5871 TQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVT 5930
TQT++T H+ NVNRFNVAITRAKVGILCIM DR +Y+ L F L+ + LQA+ T
Sbjct 5475 TQTSDTQHATNVNRFNVAITRAKVGILCIMCDRTMYENLDFYELKDSK---IGLQAKPET 5531
Query 5931 -GLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMN 5988
GLFKDCSK + P A T++S+ FKT +GL V+I KD+ Y +IS MGF+
Sbjct 5532 CGLFKDCSKSEQYIPPAYATTYMSLSDNFKTSDGLAVNIG--TKDVKYANVISYMGFRFE 5589
Query 5989 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 6048
+ GY +F TR+ A+R+VRAW+GFDVEG H + VGTN+PLQLGFS GV+ V G
Sbjct 5590 ANIPGYHTLFCTRDFAMRNVRAWLGFDVEGAHVCGDNVGTNVPLQLGFSNGVDFVVQTEG 5649
Query 6049 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 6108
V T V A+ PPG+QF HLIPLM KG PW++VR +IVQM+ D LSD ++F
Sbjct 5650 CVITEKGNSIEVVKARAPPGEQFAHLIPLMRKGQPWHIVRRRIVQMVCDYFDGLSDILIF 5709
Query 6109 VLWAHGFELTSMKYFVKIG-PERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMI 6167
VLWA G ELT+M+YFVKIG P++ C C + ATC+S++ YAC+ H++G DY+YNP+ I
Sbjct 5710 VLWAGGLELTTMRYFVKIGRPQK--CECGKSATCYSSSQSVYACFKHALGCDYLYNPYCI 5767
Query 6168 DVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDE 6227
D+QQWG+TG+L NH C +H N HVAS DAIMTRCLA+H+CFVKRVDW+I YP I +E
Sbjct 5768 DIQQWGYTGSLSMNHHEVCNIHRNEHVASGDAIMTRCLAIHDCFVKRVDWSIVYPFIDNE 5827
Query 6228 LKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYK 6287
KIN A R VQ V+KAAL +HD+GNPK I+C + W YD P ++
Sbjct 5828 EKINKAGRIVQSHVMKAALKIFNPAAIHDVGNPKGIRCA-TTPIPWFCYDRDPINN---N 5883
Query 6288 IEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVN 6347
+ L Y Y H +G+ LFWNCNVD YP SIVCRFDTR S L+L GC+GG+LYVN
Sbjct 5884 VRCLDYDYMVHGQ--MNGLMLFWNCNVDMYPEFSIVCRFDTRTRSKLSLEGCNGGALYVN 5941
Query 6348 KHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 6407
HAFHTPA+D+ AF LK +PFFYY DS CE V +YVPLKS CIT+CN+GGA
Sbjct 5942 NHAFHTPAYDRRAFAKLKPMPFFYYDDSNCE----LVDGQPNYVPLKSNVCITKCNIGGA 5997
Query 6408 VCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTR---LQSLENVAFNVVNK 6464
VC+ HA YR Y++ YN+ + AGF++W + FDTY LW+ F LQSLENVAFNVV K
Sbjct 5998 VCKKHAALYRAYVEDYNIFMQAGFTIWCPQNFDTYMLWHGFVNSKALQSLENVAFNVVKK 6057
Query 6465 GHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKIL 6524
G F G +G++P ++I + + + D +F NKT+LP NVAFEL+AKR + P + IL
Sbjct 6058 GAFTGLKGDLPTAVIADKIMVRDGPTDKCIFTNKTSLPTNVAFELYAKRKLGLTPPLTIL 6117
Query 6525 NNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVD 6584
NLGV V+WDY+ + P T VCS TD+ + + FD + G +
Sbjct 6118 RNLGVVATYKFVLWDYEAERPFSNFTKQVCSYTDLDSE--------VVTCFDNSIAGSFE 6169
Query 6585 LFRNARNGVLITEGSVKGLQPSVGPKQASLNG--VTLIGEAVKTQFNYYKKVDGVVQQLP 6642
F R+ VLI+ +VKGL ++ + LN V+ +G T + Y +K V+Q+
Sbjct 6170 RFTTTRDAVLISNNAVKGLS-AIKLQYGLLNDLPVSTVGNKPVTWYIYVRKNGEYVEQI- 6227
Query 6643 ETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHL 6702
++Y+TQ R + FKPRS ME DFL + FI++Y LE Y FEH+V+GD S + +GG+HL
Sbjct 6228 DSYYTQGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEHVVFGDVSKTTIGGMHL 6287
Query 6703 LIGLAKRFKESPFELEDFI-PMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQ 6761
LI + K F +++F+ DST+K+ IT A SSK VC+ +D+LLDDFV IIKS
Sbjct 6288 LISQVRLAKMGLFSVQEFMNNSDSTLKSCCITYADDPSSKNVCTYMDILLDDFVTIIKSL 6347
Query 6762 DLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLE 6821
DL+VVSKVV V +D +MLWC++ H++TFYP+LQS++ W PG +MP LYK+QRM LE
Sbjct 6348 DLNVVSKVVDVIVDCKAWRWMLWCENSHIKTFYPQLQSAE-WNPGYSMPTLYKIQRMCLE 6406
Query 6822 KCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTA 6881
+C+L NYG LP GI NV KYTQLCQYLNT TL VP+ MRV+H GA GVAPG+
Sbjct 6407 RCNLYNYGAQVKLPDGITTNVVKYTQLCQYLNTTTLCVPHKMRVLHLGAAGASGVAPGST 6466
Query 6882 VLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKEN 6941
VLR+WLP +LVD+DL D+VSDAD ++ GDC +++ +K+DL++SD+YD TK++ EN
Sbjct 6467 VLRRWLPDDAILVDNDLRDYVSDADFSVTGDCTSLYIEDKFDLLVSDLYDGSTKSIDGEN 6526
Query 6942 DSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSE 7001
SK+GFFTYI GFI++KL+LGGSVAIKITE SWN DLY+L+ F +WT F T+VN SSSE
Sbjct 6527 TSKDGFFTYINGFIKEKLSLGGSVAIKITEFSWNKDLYELIQRFEYWTVFCTSVNTSSSE 6586
Query 7002 AFLIGCNYLGK--PREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMS 7059
FLIG NYLG + +DG +MHANYIFWRN+ + LS S+ D KF + +++
Sbjct 6587 GFLIGINYLGPYCDKAIVDGNIMHANYIFWRNSTIMALSHNSVLDTPKFKCRCNNALIVN 6646
Query 7060 LKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
LKE ++N+M++ LL KG+L+IR N +++ + VN
Sbjct 6647 LKEKELNEMVIGLLRKGKLLIRNNGKLLNFGNHFVN 6682
Score = 62.8 bits (151), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 69/288 (24%), Positives = 123/288 (43%), Gaps = 38/288 (13%)
Query 986 QTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADI 1045
+ V QQ E+N+++ + ++ P+ + + P + +++ + G L + N
Sbjct 1293 EKVEQQPIVEENKSSIEKEEIQ-SPKNDDLILPFYKAGKLSFYQGALDVLINF------- 1344
Query 1046 VEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVL 1105
++P V+VNAAN LKH GGVA A++ T + S DY+ N + G +
Sbjct 1345 ------LEPDVIVNAANGDLKHMGGVARAIDVFTGGKLTERSKDYLKKNKSIAPGNAVFF 1398
Query 1106 SGHNLAKH--CLHVVGPNVNKGEDIQLLKSAYENFNQHE-VLLAPLLSAGIFGADPIHSL 1162
N+ +H L+ VGP L + Y+ + E +L PL+S GIF
Sbjct 1399 --ENVIEHLSVLNAVGPRNGDSRVEAKLCNVYKAIAKCEGKILTPLISVGIF-------- 1448
Query 1163 RVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKI--AEIPKEEVKPFITESKP 1220
VR L K + D+ ++ F+ E+Q + IP + + +
Sbjct 1449 -----NVRLETSLQCLLKTVNDRGLNVFVYTDQERQTIENFFSCSIPVNVTEDNVNHERV 1503
Query 1221 SVEQRKQDDKKIKACV----EEVTTTLEETKFLTENLLLYIDINGNLH 1264
SV K +++K V ++VT L + + ++ IDI+ H
Sbjct 1504 SVSFDKTYGEQLKGTVVIKDKDVTNQLPSAFDVGQKVIKAIDIDWQAH 1551
Score = 49.7 bits (117), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 57/235 (24%), Positives = 94/235 (40%), Gaps = 34/235 (14%)
Query 1656 WKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALIL 1715
+K +NG +K DNNC++ LQ + FN +A+ + + G+ +F L
Sbjct 1075 FKTTNLNGKIILKQGDNNCWINACCYQLQAFDF-FN----NEAWEKFKKGDVMDFVNLCY 1129
Query 1716 AYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
A G GD + + + + K VL C CG+++ L E ++ T
Sbjct 1130 AATTLARGHSGDAEYLLELMLN--DYSTAKIVLAAKCG-CGEKEIVL---ERAVFKLTPL 1183
Query 1776 YEQFKKGVQIPC----TCGKQATKY-------LVQQESPFVMMSAPPAQYELKHGTFTCA 1824
E F GV C TC + + ++ +++P M P + +
Sbjct 1184 KESFNYGVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHAV-------- 1235
Query 1825 SEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKP 1879
YTG Q GHY + E YC+DG + K + + + +F N T KP
Sbjct 1236 --YTGTTQNGHY-MVDDIEHGYCVDG-MGIKPLKKRCYTSTLFINANVMTRAEKP 1286
Score = 41.6 bits (96), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 103/455 (23%), Positives = 149/455 (33%), Gaps = 96/455 (21%)
Query 144 DLGDELGTDPYEDFQENWNTKHSSGVTREL-MRELNGGAYTRYVDNNFCGPDGYPL--EC 200
DL L T+P Q + +GV + ++ G YVD CG DG P+
Sbjct 71 DLKPVLLTEPSVMLQGFIVRANCNGVLEDFDLKIARTGRGAIYVDQYMCGADGKPVIEGD 130
Query 201 IKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLA 260
KD D I+ + Y C AW T R EK QT F I+
Sbjct 131 FKDYFGDE-----------DIIEFEGEEYHC-------AWTTVRDEKPLNQQTLFTIQEI 172
Query 261 KKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVY-----PVASPNECNQM 315
+ +N + P+ P N + + P V+K + +Y P +C
Sbjct 173 Q----YNLDIPH-KLP-NCATRHVAPPVKKNSKIVLSEDYKKLYDIFGSPFMGNGDCLSK 226
Query 316 CLSTL------MKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIY 369
C TL ++C CG S GD+ CG K G T P +AVV
Sbjct 227 CFDTLHFIAATLRCP-CGSESSGVGDWTGFKTACCGLSGKVK-GVTLGDIKPGDAVV--- 281
Query 370 CPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASA 429
T + G F CV Y G + W +
Sbjct 282 -------------------------TSMSAGKGVKFFANCVLQYAGDVEGVSIW--KVIK 314
Query 430 NIGCNHTGVVGEGSEGLNDNLLEILQKEKVNIN-----IVGDFKLNEEIAIILASFSAST 484
+ T V G EG ++ ++ K V + I GD II ST
Sbjct 315 TFTVDET-VCTPGFEGELNDFIKPESKSLVACSVKRAFITGDIDDAVHDCIITGKLDLST 373
Query 485 SAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQ---------KSILSPLYA 535
+ F GL +K V+ CG V AW + E+ K I + +
Sbjct 374 NLFGNV--GLLFKKTPWFVQKCGALFVD-------AWKVVEELCGSLTLTYKQIYEVVAS 424
Query 536 FASEAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
+ A +V + T N V+ L + +L
Sbjct 425 LCTSAFTIVN--YKPTFVVPDNRVKDLVDKCVKVL 457
Score = 37.4 bits (85), Expect = 8.8, Method: Compositional matrix adjust.
Identities = 61/286 (21%), Positives = 107/286 (37%), Gaps = 29/286 (10%)
Query 1567 TIKVFTTVDNINLHTQVVDMSMTYGQQF-GPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+I V T DN+N V TYG+Q G + DVT P G+
Sbjct 1488 SIPVNVTEDNVNHERVSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAFDVGQKVI-----K 1542
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSI--KWADNNCYLATALLTL 1683
+ ++ +Y D + SA +H +K+ V I K DNNC++ L L
Sbjct 1543 AIDIDWQAHYGFRDAAAF----SASSH-DAYKFEVVTHSNFIVHKQTDNNCWINAICLAL 1597
Query 1684 QQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDS 1743
Q+++ ++ P ++ + + F ++ GE GD E M + +
Sbjct 1598 QRLKPQWKFPGVRGLWNEFLERKTQGFVHMLYHISGVKKGEPGDA-ELMLHKLGDLMDND 1656
Query 1744 CKRVL--NVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQE 1801
C+ ++ C C + + + V A L+ G C G + Q +
Sbjct 1657 CEIIVTHTTACDKCAKVEKFVGPVVA----APLAIH----GTDETCVHGVSVNVKVTQIK 1708
Query 1802 SPFVMMS--APPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETL 1845
+ S P L+ + C Y+G+ + GHY + ++ L
Sbjct 1709 GTVAITSLIGPIIGEVLEATGYIC---YSGSNRNGHYTYYDNRNGL 1751
>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709
Score = 4188 bits (10862), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2238/4943 (45%), Positives = 3067/4943 (62%), Gaps = 199/4943 (4%)
Query 2214 SFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNS 2273
+ NY++ N L I LLL + L Y ++ V+ C+G + Y NS
Sbjct 1903 TLNYVRQLNKPALWRYIKLVLLL-IALYHFFYLFVSIPVVHK-----LACSGSVQAYSNS 1956
Query 2274 TNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWD----LTAFGLVAEWFL 2329
+ V + C SI C CL+ D L + L+ S W+ L+ F +A +
Sbjct 1957 SFVK-SEVCGNSILCKACLASYDELADFDHLQVSWDYKSDPLWNRVIQLSYFIFLAVFGN 2015
Query 2330 AYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFAS 2389
Y+ ++V + + L+ SYF ++ SW + ++V IS + +
Sbjct 2016 NYVRCLLMYFV---SQYLNLWLSYFG--YVKYSWFL----HVVNFESISVEFVIIVVVFK 2066
Query 2390 FYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHN 2449
K H+ CN+ +C C K R TR+ +VNG ++ YV+ANG CK HN
Sbjct 2067 AVLALK---HIFLPCNNPSCKTCSKIARQTRIPIQVVVNGSMKTVYVHANGTGKLCKKHN 2123
Query 2450 WNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLY----- 2504
+ C NCD++ TFI DE+ RDLS K+ + TD+S V V +G Y
Sbjct 2124 FYCKNCDSYGFDHTFICDEIVRDLSNSIKQTVYATDRSYQEVTKVECTDGFYRFYVGEEF 2183
Query 2505 ----FDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVY 2560
+D +K + L LD+ N GS +S ++ VY
Sbjct 2184 TAYDYDVKHKKYSSQEVLKTMFLLDDFIVYNPSGS--------------SLASVRNVCVY 2229
Query 2561 YSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAEL 2620
+SQL+ +PI +++ L+ D+ S + +F+A N ++FNV + + K L E
Sbjct 2230 FSQLIGRPIKIVNSELLEDL--SVDFKGALFNAKKNVIKNSFNVDVSECKNL-----EEC 2282
Query 2621 AKNVSLDNVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNK- 2679
K +LD STF A +H+ I +T S NN+ + K
Sbjct 2283 YKLCNLDVTFSTFEMAINN------------------AHRFGILITDRSFNNFWPSKIKP 2324
Query 2680 -VENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNL 2738
++ D+G C+ A+ +NA+V +++W +DF +LS +K + + +
Sbjct 2325 GSSGVSAMDIGKCMTFDAKIVNAKVLTQRGKSVVWLSQDFSTLSSTAQKVLVKTFVEEGV 2384
Query 2739 PFKLTCATTRQVVNV----VTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVH 2794
F LT ++ T ++ K G + LKQL ++ + ++ L +
Sbjct 2385 NFSLTFNAVGSDEDLPYERFTESVSAKSGSGFFDVLKQLKQLFWCLVLFITLYGLCSVYS 2444
Query 2795 VMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSY-TNDKACPL 2853
V ++ S+E Y I GV + + C N + F WF + G T DK+CP+
Sbjct 2445 VATQSYIDSAEGYDYMVIKNGVVQSFDDSINCVHNTYKGFAVWFKAKHGFVPTFDKSCPI 2504
Query 2854 IAAVITREVGFV--VPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
+ + ++G + +P +P + G L F V N+CY + +
Sbjct 2505 VLGTVF-DLGNMRPIPDVPAYVALV--GRSLVFAINAAFGVTNVCYDHTGAAVSKNSYFD 2561
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEG 2971
CV + CT G V YC ++EG+ Y L PD Y G++++ P
Sbjct 2562 TCVFNSACTTLTGIGGTVV-YCAKQGLVEGAKLYSELLPDYYYEHASGNMVKIPAIIRSF 2620
Query 2972 SVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMF 3031
+R V T + YCR G C S+AG C +V + ++ G CG + N+F
Sbjct 2621 GLRFVKTQATTYCRVGECTESQAGFCFGGDNWFVYDKEFG---DGYICGSSTLGFFKNVF 2677
Query 3032 TPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTV 3091
+ + S +++A ++A + + Y ++F++ FG+ TLL +M
Sbjct 2678 ALFNSNMSVVATSGAMLANIVIACLAIAVCYGVLKFKKIFGDC-------TLLVVMIIVT 2730
Query 3092 LCLTPVYSFLPG--VYSVIYLYLTFYLTNDVSFLAHIQ--WMVMFTPLVPFWITIAYIIC 3147
L + V F+ + ++Y + ++ T +++ + +++ + + P+++ + YI+
Sbjct 2731 LVVNNVSYFVTQNTFFMIVYAIIYYFTTRKLAYPGVLDAGFIIAYLNMAPWYVLVLYIMV 2790
Query 3148 ISTKHFYWFFSNYLKRRV---VFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQ 3203
Y + K +V +F G F +FE AA+ TF+++ Y L + L +
Sbjct 2791 F----LYDSLPSLFKLKVTTNLFEGDKFVGSFESAAMGTFVIDMRSYETLVNST--SLDR 2844
Query 3204 YNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQ 3263
Y +NKYKY++G+M YR A HL KAL D+S S +D+LY PP S+ S LQ
Sbjct 2845 IKSYANSFNKYKYYTGSMGEADYRMACYAHLGKALMDYSVSRNDMLYTPPTVSVNST-LQ 2903
Query 3264 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 3323
SG RKMA PSG VE C+V+V G LNGLWL D V CPRHVI + + NYE+ L
Sbjct 2904 SGLRKMAQPSGVVEPCIVRVAYGNNVLNGLWLGDEVICPRHVIASDTSRV-INYENELSS 2962
Query 3324 KSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNG 3383
HNF + N L V+ + L LKV+ NP TP++KF ++PG++F++LACY G
Sbjct 2963 VRLHNFSIAKNNAFLGVVSAKYKGVNLVLKVNQVNPNTPEHKFKSVRPGESFNILACYEG 3022
Query 3384 SPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGN 3443
P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++LEG
Sbjct 3023 CPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGTLYFVYMHHLELGNGSHVGSNLEGE 3082
Query 3444 FYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3503
YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + TL +N A ++
Sbjct 3083 MYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMTLESYNAWAKTNSFT 3142
Query 3504 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 3563
+ D L+A+TG +V + + L G GRTIL L DEFTP +V+RQ
Sbjct 3143 EIVS--TDAFNMLAAKTGYSVEKLLECIVRL-NKGFGGRTILSYGSLCDEFTPTEVIRQM 3199
Query 3564 SGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLY------ENAFLPFAMG 3617
GV QS ++I ++T++ +L + L FF+Y F+ +
Sbjct 3200 YGVNLQSGKVKSI-------FYPMMTAIAILFA---FWLEFFMYTPFTWINPTFVSVVLA 3249
Query 3618 IIAM-SAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSG 3676
I + S + +KHK F F++PS+ N+V+ ++ + ++ V+T+
Sbjct 3250 ITTLVSVLLVAGIKHKMLFFMSFVMPSVILATAHNVVW-DMTYYESLQVLVENVNTTFLP 3308
Query 3677 FKLKDCVMYASAVVLLILMTAR------TVYDDGARRVWTLMNVLTLVYKVYYGNALDQ- 3729
++ ++ VV+ ++ T R + + A ++ + N++ L+ + D
Sbjct 3309 VDMQGVMLALFCVVVFVICTIRFFTCKQSWFSLFATTIFVMFNIVKLLGMIGEPWTDDHF 3368
Query 3730 ---AISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFL 3786
++M ++IS+T+ VV +A IV ++ P F ++C+ ++Y
Sbjct 3369 LLCLVNMLTMLISLTTKDWFVVFASYKVAYYIVVYVMQ--PAFVQDFGFVKCVSIIYMAC 3426
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
GY CY+G+ +NR+ +T GVY + VS E +YM + L PK + DA L+ KL+G
Sbjct 3427 GYLFCCYYGILYWVNRFTCMTCGVYQFTVSPAELKYMTANNLSAPKTAYDAMILSFKLMG 3486
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG IK++TVQSK++++KCT+VVLL +L ++ VES+SK W CV LHN+I L D
Sbjct 3487 IGGGRNIKISTVQSKLTEMKCTNVVLLGLLSKMHVESNSKEWNYCVGLHNEINLCDDPDA 3546
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
EK+++L++ LS D++ L E +N LQ++AS +++LPS+ A+ A+ E+
Sbjct 3547 VLEKLLALIAFFLSKHNTCDLSDLIESYFENTTILQSVASAYAALPSWIAYEKARADLEE 3606
Query 3967 AVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVT 4026
A N S +LK+L K+ N+AKSEF+R+A++Q+KL+KMA+QA MYK+AR+ D+++K+
Sbjct 3607 AKKNDVSPQLLKQLTKACNIAKSEFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIV 3666
Query 4027 SAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDG 4086
SAM ++LF ML+KLD ++N II AR+G +PL+IIP +A +L+VV P+
Sbjct 3667 SAMHSLLFGMLKKLDMSSVNTIIEQARNGVLPLSIIPAASATRLIVVTPNLEVLSKVRQE 3726
Query 4087 TTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSP 4146
YA A+W I +V DA+ V L E++ N N+ WPL +T R KLQNNE+ P
Sbjct 3727 NNVHYAGAIWSIVEVKDANGAQVHLKEVTAANELNITWPLSITCERT---TKLQNNEILP 3783
Query 4147 VALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIY 4206
L++ + A T + A + G F+ A ++ +LK+ ++ ++ I
Sbjct 3784 GKLKEKAVKASATIDGDAYGSGKALMASEGGKSFIYAFIASDSNLKYVKWESNNDV--IP 3841
Query 4207 TELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTV 4266
ELE P RF D GP+VKYLYF+K LN L RG VLG + ATVRLQAG TE P+NS +
Sbjct 3842 IELEAPLRFYVDGVNGPEVKYLYFVKSLNTLRRGAVLGYIGATVRLQAGKPTEHPSNSGL 3901
Query 4267 LSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASC 4326
L+ CAFA D AKAY D + G QP+TNCVKML G G AIT E+N Q+S+GGAS
Sbjct 3902 LTLCAFAPDPAKAYVDAVKRGMQPVTNCVKMLSNGAGNGMAITNGVESNTQQDSYGGASV 3961
Query 4327 CLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQL 4386
C+YCRCH++HP G C KGK+VQ+PT DP+ F ++N VC VCG W GC CD
Sbjct 3962 CIYCRCHVEHPAIDGLCRFKGKFVQVPTG-TQDPIRFCIENEVCVVCGCWLTNGCMCD-- 4018
Query 4387 REPMLQSADAQSFLNRVCGVSAA-RLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNC 4445
R + + QS+LN CGV L PC GT D V RAFDIYN VA KFLKTNC
Sbjct 4019 RTSIQGTTIDQSYLNE-CGVLVQLDLEPC-NGTDPDHVSRAFDIYNKDVACIGKFLKTNC 4076
Query 4446 CRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPH 4505
RF+ D+ D +Y+VVKR T S HE+ YN LKD VA+HDFF ++ +
Sbjct 4077 SRFRNLDKHD----AYYVVKRCTKSVMDHEQVCYNDLKDSGVVAEHDFFLYKEGRCEFGN 4132
Query 4506 ISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILR 4565
++R+ LTKYTM DL YA+R+FDE NC+ LKEILVT C++ +F KDW+D VEN I
Sbjct 4133 VARKDLTKYTMMDLCYAIRNFDEKNCEVLKEILVTLGACNESFFENKDWFDPVENEAIHE 4192
Query 4566 VYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPV 4625
VYA LG V A+LK V FCDA+ G +G++TLDNQDLNGN+YDFGDF++TTPG G
Sbjct 4193 VYARLGPIVANAMLKCVAFCDAIVEKGYIGIITLDNQDLNGNFYDFGDFVKTTPGFGCAC 4252
Query 4626 VDSYYSLLMPILTLTRALTAESHVDTDL-TKPYIKWDLLKYDFTEERLKLFDRYFKYWDQ 4684
V SYYS +MP++ +T L +E+ V +D+ Y ++DLL YDFT+ + KLF +YFK+WD+
Sbjct 4253 VTSYYSYMMPLMGMTSCLESENFVKSDIYGADYKQYDLLAYDFTDHKEKLFHKYFKHWDR 4312
Query 4685 TYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELG 4744
TYHPNC +C D CI+HCANFN LFS P T+FGPLVRK+ +DGVP VV+ GYHF++LG
Sbjct 4313 TYHPNCSDCTSDECIIHCANFNTLFSMTIPSTAFGPLVRKVHIDGVPVVVTAGYHFKQLG 4372
Query 4745 VVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKP 4804
+V N DV L + +LS +LL + DP + AS LLD+RT CFS+AAL+ V +QTVKP
Sbjct 4373 IVWNLDVKLDTMKLSMTDLLRFVTDPTLLVASSPALLDQRTVCFSIAALSTGVTYQTVKP 4432
Query 4805 GNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFV 4864
G+FNKDFYDF +GFF+EGS + LKHFFFAQ G AA++D++YYRYN T+ DI Q FV
Sbjct 4433 GHFNKDFYDFITERGFFEEGSELTLKHFFFAQGGEAAMTDFNYYRYNRVTVLDICQAQFV 4492
Query 4865 VEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTK 4924
++V KYF+CYDGGCINA +V+V N DKSAG+P NK+GKARLYY+++SYE+QDALFA TK
Sbjct 4493 YKIVGKYFECYDGGCINAREVVVTNYDKSAGYPLNKFGKARLYYETLSYEEQDALFALTK 4552
Query 4925 RNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTS 4984
RNV+PT+TQMNLKYAIS K RARTV GVS+ STMT RQ+HQK LKSIAATR ATVVIG++
Sbjct 4553 RNVLPTMTQMNLKYAISGKARARTVGGVSLLSTMTTRQYHQKHLKSIAATRNATVVIGST 4612
Query 4985 KFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRF 5044
KFYGGW NMLK + DV+N LMGWDYPKCDRA+PNM+R+ ++++L KH CC+ S RF
Sbjct 4613 KFYGGWDNMLKNLMRDVDNGCLMGWDYPKCDRALPNMIRMASAMILGSKHVGCCTHSDRF 4672
Query 5045 YRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDG 5104
YRL+NE AQVL+E+V C G Y KPGGT+SGD TTAYANS FNI QAV+ANVN LL D
Sbjct 4673 YRLSNELAQVLTEVVHCTGGFYFKPGGTTSGDGTTAYANSAFNIFQAVSANVNKLLGVDS 4732
Query 5105 NKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYAS 5164
N + V+++Q ++Y+ YR+ +D +FV E+++YLRKHFSMMILSDD VVC+N YA
Sbjct 4733 NACNNVTVKSIQRKIYDNCYRSSSIDEEFVVEYFSYLRKHFSMMILSDDGVVCYNKDYAD 4792
Query 5165 QGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYP 5224
G VA I FK+ LYYQNNVFMS +KCW E DL+ GPHEFCSQHT+ + D YLPYP
Sbjct 4793 LGYVADINAFKATLYYQNNVFMSTSKCWVEPDLSVGPHEFCSQHTLQIVGPDGDYYLPYP 4852
Query 5225 DPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLH 5284
DPSRIL AG FVDDIVKTD +M+ER+VSLAIDAYPLTKHP Y VF+ L +++ L
Sbjct 4853 DPSRILSAGVFVDDIVKTDNVIMLERYVSLAIDAYPLTKHPKPAYQKVFYTLLDWVKHLQ 4912
Query 5285 DELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACI 5344
L +LD +SV + + ++W EFY ++Y TVLQA G CV+C SQT LRCG C+
Sbjct 4913 KNLNAGVLDSFSVTMLEEGQDKFWSEEFYASLYEKSTVLQAAGMCVVCGSQTVLRCGDCL 4972
Query 5345 RRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPIS 5404
RRP LC KC YDHV+ T HK ++S+ PYVC+ GC+V DVT+L+LGG+SYYC HKP +S
Sbjct 4973 RRPLLCTKCAYDHVMGTKHKFIMSITPYVCSFNGCNVNDVTKLFLGGLSYYCMDHKPQLS 5032
Query 5405 FPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKA 5464
FPLCANG VFGLYK++ VGS++V DFN +A DWTN DY LAN E LK+FAAET+KA
Sbjct 5033 FPLCANGNVFGLYKSSAVGSEDVEDFNKLAVSDWTNVEDYKLANNVKESLKIFAAETVKA 5092
Query 5465 TEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTF 5524
EE+ K Y A ++EV+ +E+ L WE K +PPLNRN VFT ++++K++K+Q+GE+ F
Sbjct 5093 KEESVKSEYAYAILKEVIGPKEIVLQWEASKTKPPLNRNSVFTCFQISKDTKIQLGEFVF 5152
Query 5525 EKGDYG-DAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNIS 5583
E+ +YG D+V Y+ T+TYKL G FVLTSH V PL A LV QE Y I+ LYP NI+
Sbjct 5153 EQSEYGSDSVYYKSTSTYKLTPGMIFVLTSHNVSPLKATILVNQEKYNTISKLYPVFNIA 5212
Query 5584 DEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCE 5643
+ +++ V YQ +G QK++T+QGPPG+GKSH IGL LYYP ARIVYTACSHAAVDALCE
Sbjct 5213 EAYNTLVPYYQMIGKQKFTTIQGPPGSGKSHCVIGLGLYYPQARIVYTACSHAAVDALCE 5272
Query 5644 KALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMA 5703
KA K +D+CSRIIP R RV+C+ FK N+T QY+FCTVNALPE + DIVV DE+SM
Sbjct 5273 KAAKNFNVDRCSRIIPQRIRVDCYTGFKPNNTNAQYLFCTVNALPEASCDIVVVDEVSMC 5332
Query 5704 TNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLG 5763
TNYDLSV+N+RL KH VY+GDP QLPAPRTL+ KG L+P+ +N V + + T+GPD+FL
Sbjct 5333 TNYDLSVINSRLSYKHIVYVGDPQQLPAPRTLINKGVLQPQDYNVVTQRVCTLGPDVFLH 5392
Query 5764 TCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREF 5823
C RCPAEIV TVSALVY+NK +S QCFKMF KG + + +S+IN Q+ VV+ F
Sbjct 5393 KCYRCPAEIVKTVSALVYENKFVPVNPESKQCFKMFVKGQVQIESNSSINNKQLEVVKAF 5452
Query 5824 LTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVN 5883
L NP WRKAVFISPYNSQN VA ++LGL TQTVDS+QGSEYDYVI+TQT++T H+ NVN
Sbjct 5453 LAHNPKWRKAVFISPYNSQNYVARRLLGLQTQTVDSAQGSEYDYVIYTQTSDTQHATNVN 5512
Query 5884 RFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVT-GLFKDCSKVITG 5942
RFNVAITRAKVGILCIM DR +Y+ L F L+ + LQA+ T GLFKDCSK
Sbjct 5513 RFNVAITRAKVGILCIMCDRTMYENLDFYELKDSK---IGLQAKPETCGLFKDCSKSEQY 5569
Query 5943 LHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITR 6001
+ P A T++S+ FKT +GL V+I KD+ Y +IS MGF+ + GY +F TR
Sbjct 5570 IPPAYATTYMSLSDNFKTSDGLAVNIG--TKDVKYANVISYMGFRFEANIPGYHTLFCTR 5627
Query 6002 EEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRV 6061
+ A+R+VRAW+GFDVEG H + VGTN+PLQLGFS GV+ V G V T V
Sbjct 5628 DFAMRNVRAWLGFDVEGAHVCGDNVGTNVPLQLGFSNGVDFVVQTEGCVVTEKGNSIEVV 5687
Query 6062 SAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMK 6121
A+ PPG+QF HLIPLM KG PW++VR +IVQM+ D LSD ++FVLWA G ELT+M+
Sbjct 5688 KARAPPGEQFAHLIPLMRKGQPWHIVRRRIVQMVCDYFDGLSDILIFVLWAGGLELTTMR 5747
Query 6122 YFVKIG-PERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQS 6180
YFVKIG P++ C C + ATC+S++ YAC+ H++G DY+YNP+ ID+QQWG+TG+L
Sbjct 5748 YFVKIGRPQK--CECGKSATCYSSSQCVYACFKHALGCDYLYNPYCIDIQQWGYTGSLSM 5805
Query 6181 NHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHM 6240
NH C +H N HVAS DAIMTRCLA+H+CFVKRVDW+I YP I +E KIN A R VQ
Sbjct 5806 NHHEVCNIHRNEHVASGDAIMTRCLAIHDCFVKRVDWSIVYPFIDNEEKINKAGRIVQSH 5865
Query 6241 VVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSD 6300
V+KAAL +HD+GNPK I+C + W YD P ++ +E Y Y H
Sbjct 5866 VMKAALKIFNPAAIHDVGNPKGIRCA-TTPIPWFCYDRDPINNNVRCLE---YDYMVHGQ 5921
Query 6301 KFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSA 6360
+G+ LFWNCNVD YP SIVCRFDTR S L+L GC+GG+LYVN HAFHTPA+D+ A
Sbjct 5922 --MNGLMLFWNCNVDMYPEFSIVCRFDTRTRSKLSLEGCNGGALYVNNHAFHTPAYDRRA 5979
Query 6361 FVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYL 6420
F LK +PFFYY DS CE V +YVPLKS CIT+CN+GGAVC+ HA YR Y+
Sbjct 5980 FAKLKPMPFFYYDDSNCE----LVDGQPNYVPLKSNVCITKCNIGGAVCKKHAALYRAYV 6035
Query 6421 DAYNMMISAGFSLWVYKQFDTYNLWNTFTR---LQSLENVAFNVVNKGHFDGQQGEVPVS 6477
+ YNM + AGF++W + FDTY LW+ F LQSLENVAFNVV KG F G +G++P +
Sbjct 6036 EDYNMFMQAGFTIWCPQNFDTYMLWHGFVNSKALQSLENVAFNVVKKGAFTGLKGDLPTA 6095
Query 6478 IINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVI 6537
+I + + + D +F NKT+LP NVAFEL+AKR + P + IL NLGV V+
Sbjct 6096 VIADKIMVRDGPTDKCIFTNKTSLPTNVAFELYAKRKLGLTPPLTILRNLGVVATYKFVL 6155
Query 6538 WDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITE 6597
WDY+ + P T VCS TD+ + + FD + G + F ++ VLI+
Sbjct 6156 WDYEAECPFSNFTKQVCSYTDLDSE--------VVTCFDNSIAGSFERFTTTKDAVLISN 6207
Query 6598 GSVKGLQPSVGPKQASLNG--VTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEF 6655
+VKGL ++ + LN V+ +G T + Y +K V+Q+ ++Y+T R + F
Sbjct 6208 NAVKGLS-AIKLQYGFLNDLPVSTVGNKPVTWYIYVRKNGEYVEQI-DSYYTHGRTFETF 6265
Query 6656 KPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPF 6715
KPRS ME DFL + FI++Y LE Y FEH+V+GD S + +GG+HLLI + K F
Sbjct 6266 KPRSTMEEDFLSMDTTLFIQKYGLEDYGFEHVVFGDVSKTTIGGMHLLISQVRLAKMGLF 6325
Query 6716 ELEDFIP-MDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTI 6774
+++F+ DST+K+ IT A SSK VC+ +D+LLDDFV IIKS DL+VVSKVV V +
Sbjct 6326 SVQEFMTNSDSTLKSCCITYADDPSSKNVCTYMDILLDDFVTIIKSLDLNVVSKVVDVIV 6385
Query 6775 DYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATL 6834
D +MLWC++ ++TFYP+LQS++ W PG +MP LYK+QRM LE+C+L NYG L
Sbjct 6386 DCKAWRWMLWCENSQIKTFYPQLQSAE-WNPGYSMPTLYKIQRMCLERCNLYNYGAQVRL 6444
Query 6835 PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLV 6894
P GI NV KYTQLCQYLNT T+ VP+ MRV+H GA GVAPG+ VLR+WLP +LV
Sbjct 6445 PDGITTNVVKYTQLCQYLNTTTVCVPHKMRVLHLGAAGASGVAPGSTVLRRWLPDDAILV 6504
Query 6895 DSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGF 6954
D+DL D+VSDAD ++ GDC +++ +K+DL+ISD+YD TK++ EN SK+GFFTYI GF
Sbjct 6505 DNDLRDYVSDADFSVTGDCTSLYIEDKFDLLISDLYDGSTKSIDGENTSKDGFFTYINGF 6564
Query 6955 IQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGK-- 7012
I++KL+LGGS AIKITE SWN DLY+L+ F +WT F T+VN SSSE FLIG NYLG
Sbjct 6565 IKEKLSLGGSAAIKITEFSWNKDLYELIQRFEYWTVFCTSVNTSSSEGFLIGINYLGPYC 6624
Query 7013 PREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSL 7072
+ +DG +MHANYIFWRN+ + LS S+ D KF + +++LKE ++N+M++ L
Sbjct 6625 DKAIVDGNIMHANYIFWRNSTIMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVVGL 6684
Query 7073 LSKGRLIIRENNRVVISSDVLVN 7095
L KG+L+IR N +++ + LVN
Sbjct 6685 LRKGKLLIRNNGKLLNFGNHLVN 6707
Score = 54.7 bits (130), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 55/231 (24%), Positives = 105/231 (45%), Gaps = 27/231 (12%)
Query 1052 VKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA 1111
++P V+VNAAN L+H GGVA A++ T + S +Y+ ++ + G + + N+
Sbjct 1356 LEPDVLVNAANGDLRHVGGVARAIDVFTGGKLTKRSKEYLKSSKAIAPGNAVLF--ENVL 1413
Query 1112 KH--CLHVVGPNVNKGEDIQLLKSAYENFNQHE-VLLAPLLSAGIFGADPIHSLRVCVDT 1168
+H L+ VGP L + Y+ + + +L PL+S GIF
Sbjct 1414 EHLSVLNAVGPRNGDSRVEGKLCNVYKAIAKCDGKILTPLISVGIF-------------K 1460
Query 1169 VRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKI--AEIPKEEVKPFITESKPSVEQRK 1226
V+ V L K + D+ ++ F+ E+ + IP + + + + + SV K
Sbjct 1461 VKLEVSLQCLLKTVTDRDLNVFVYTDQERVTIENFFNGTIPIKVTEDTVNQKRVSVALDK 1520
Query 1227 QDDKKIKACV----EEVTTTLEETKFLTENLLLYIDINGNLH---PDSATL 1270
+++K V ++VT L + E ++ +D++ N + P++A
Sbjct 1521 TYGEQLKGTVVIKDKDVTNQLPSVSDVGEKVVKALDVDWNAYYGFPNAAAF 1571
Score = 44.7 bits (104), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 49/198 (25%), Positives = 80/198 (40%), Gaps = 14/198 (7%)
Query 1567 TIKVFTTVDNINLHTQVVDMSMTYGQQF-GPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
TI + T D +N V + TYG+Q G + DVT P S G+
Sbjct 1499 TIPIKVTEDTVNQKRVSVALDKTYGEQLKGTVVIKDKDVTNQLPSVSDVGEKVV-----K 1553
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQV--NGLTSIKWADNNCYLATALLTL 1683
L V+ YY + + SA +H +++ V N K DNNC++ L L
Sbjct 1554 ALDVDWNAYYGFPNAAAF----SASSH-DAYEFDVVTHNNFIVHKQTDNNCWVNAICLAL 1608
Query 1684 QQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDS 1743
Q+++ + P ++ + + A F ++ T G+ GD T+ L + DS
Sbjct 1609 QRLKPTWKFPGVKSLWDAFLTRKTAGFVHMLYHISGLTKGQPGDAELTLHKLVDLMSSDS 1668
Query 1744 CKRVLN-VVCKTCGQQQT 1760
V + C C + +T
Sbjct 1669 AVTVTHTTACDKCAKVET 1686
Score = 42.4 bits (98), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 71/277 (26%), Positives = 109/277 (39%), Gaps = 26/277 (9%)
Query 1656 WKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALIL 1715
+K +NG +K DNNC++ LQ + FN L D + + +FC L
Sbjct 1099 FKTTNLNGKIILKQQDNNCWINACCYQLQAFDF-FNHD-LWDGFKKDDVMPFVDFCYAAL 1156
Query 1716 AYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
G+ + ETM + A K L+ C CG ++ L E ++ T
Sbjct 1157 TLKQGDSGDAEYLLETMLNDYSTA-----KVTLSAKCG-CGVKEIVL---ERTVFKLTPL 1207
Query 1776 YEQFKKGVQIPCTCGKQATKYLVQQESPFVM----MSAPPAQYELKHGTFTCASEYTGNY 1831
+FK GV C V+ FV P +Q+ + T T + YTG
Sbjct 1208 RNEFKYGVCGDCKQINMCKFASVEGSGVFVHDRIEKQTPVSQFIV---TPTMHAVYTGTT 1264
Query 1832 QCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYT----TTIKPVTYKLDGV 1887
Q GHY I YC+DG + K ++K + +F N T T ++P D
Sbjct 1265 QSGHY-MIEDCIHDYCVDG-MGIKPRKHKFYTSTLFLNANVMTAKSKTMVEPPVPVEDKC 1322
Query 1888 VCTEIDPK--LDNYYKKDNSYFTEQPIDLVPNQPYPN 1922
V PK + +YK F + +D++ N P+
Sbjct 1323 VEDCQSPKDLILPFYKAGKVSFYQGDLDVLINFLEPD 1359
Score = 37.7 bits (86), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 59/234 (25%), Positives = 83/234 (35%), Gaps = 34/234 (15%)
Query 144 DLGDELGTDPYEDFQENWNTKHSSGVTREL-MRELNGGAYTRYVDNNFCGPDGYPLECIK 202
DL L T+P Q + +GV + ++ G YVD CG DG P+
Sbjct 71 DLKPVLLTEPSVMLQGFIVRANCNGVLEDFDLKFARTGNGAIYVDQYMCGADGKPV---- 126
Query 203 DLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKK 262
E D+ + V E+ AW T R EK QT I+ +
Sbjct 127 -----------IEGEFKDYFGDE-DVIIYEGEEYHCAWLTVRDEKPLWQQTLLTIREIQ- 173
Query 263 FDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPV-ASPNECNQMCLSTLM 321
+N + P+ P N I+ + P V+K R +Y + SP N L+T
Sbjct 174 ---YNLDIPH-KLP-NCAIREVAPPVKKNSKVVLSEEYRKLYDIFGSPFMGNGDSLNTCF 228
Query 322 KCDH---------CGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVV 366
H CG S GD+ CG K G T P +A+V
Sbjct 229 DSLHFIAATLKCPCGAESSGVGDWTGFKTACCGLHGKVK-GVTLGAVKPGDAIV 281
>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1
SV=1
Length=6629
Score = 4156 bits (10779), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2290/5157 (44%), Positives = 3140/5157 (61%), Gaps = 298/5157 (6%)
Query 2080 ANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIA 2139
A N +K+ +++G + ++ + KPN L R+ + A G + V + I
Sbjct 1626 AENFVKMGDKIGGVTMGLWRAEH----LNKPN-LERIFNIAKKAIVGSSVVTTQCGKLIG 1680
Query 2140 NYAKPFLNKVVSTTTNIVTRCLNRVC--------TNYMPYFF-TLLLQLCTFTRSTNSRI 2190
A +KV +T + +C P F TL+ L F +++ +
Sbjct 1681 KAATFIADKVGGGVVRNITDSIKGLCGITRGHFERKMSPQFLKTLMFFLFYFLKASVKSV 1740
Query 2191 KASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAAL 2250
AS T + K + ++ +I+WF+ S ++++ +
Sbjct 1741 VASYKTVLCKVVLATL----------------------LIVWFVYTS---NPVMFTGIRV 1775
Query 2251 GVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQIT 2310
+ L S C Y++ +S +V YC C VCL DSL Y +++
Sbjct 1776 ---LDFLFEGSLCGPYKDYGKDSFDVL--RYCADDFICRVCLHDKDSLHLYKHAYSVEQV 1830
Query 2311 ISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAIMQLFFSYFAVHFISNSWLMWLI 2368
A G + W Y++F F V G I Y + + NS ++
Sbjct 1831 YKD-----AASGFIFNWNWLYLVFLILFVKPVAGFVII-----CYCVKYLVLNSTVLQTG 1880
Query 2369 INLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVVDGCNSSTCMMCYKRNRATRVEC 2423
+ + + + + F + +Y W Y VH + C TC +C + R+ R E
Sbjct 1881 VCFLDWF-VQTVFSHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEV 1939
Query 2424 TTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINP 2483
+ +V G ++ +VY N G FCK HNW C NCD + +TF+S EVA +LS + KR + P
Sbjct 1940 SVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKP 1999
Query 2484 TDQSSYIVDSVTVKNGSIHLYFDKAGQ-KTYERHSLSHFVNLDNLR-ANNTKGSLPINVI 2541
T + ++VD + + ++L + A K ++ F D L+ A K +L I
Sbjct 2000 TAYAYHVVDEACLVDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQI 2059
Query 2542 VFDGKSKCEESSA------KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYV 2595
DG C SA K+A++YY+Q +C+PIL+LDQAL +
Sbjct 2060 SNDGFIVCNTQSAHALEEAKNAAIYYAQYLCKPILILDQALYEQL--------------- 2104
Query 2596 NTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVECL 2655
V K+++ + L+ +S+D + + + + S + ++ V+
Sbjct 2105 --------VVEPVSKSVIDKVCSILSSIISVDTAALNYKAGTLRDALLSITKDEEAVDMA 2156
Query 2656 KLSHQSDIEVTGDSCNNYMLTYN-KVENMTPRDLGACIDCSARHINAQVAKSHNIALIWN 2714
H D++ TGD N + +Y +TPRD G I+ A N +V + + +W
Sbjct 2157 IFCHNHDVDYTGDGFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAPPV--VWK 2214
Query 2715 VKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL--KGGKIVNN---W 2769
+ + LS+ K + SA K+ + F +T + +QV+ T K+ + K G IV+
Sbjct 2215 FSELIKLSDSCLKYLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKC 2274
Query 2770 LKQLIKVTLVF--LFVA---AIFYLITPVHVMSKHTDFSS--EIIGYKAIDGGVTRDIAS 2822
K K L+F LF A +Y+ + D +S + G+K ID GV R+I
Sbjct 2275 FKSYFKWLLIFYILFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVP 2334
Query 2823 TDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNG-DF 2881
DTCF+NK +FD ++ G Y N + CP++ AVI + G V G+PG + +G F
Sbjct 2335 EDTCFSNKFVNFDAFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMF 2390
Query 2882 LH---------FLPRVFSA--VGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPV 2930
+H ++P F+ VG YT +I F TS + +A C ++ AS P
Sbjct 2391 IHMTQTERKPWYIPTWFNREIVG---YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQ 2446
Query 2931 PYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTC 2989
YC++ N G++ + S+ P Y +G + P L V DS YCR C
Sbjct 2447 LYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQILHTPYVVKFVSDS-YCRGSVC 2505
Query 2990 ERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVA 3049
E + G CVS + +WVL ND Y S PGVFCG L+ +M + + +I +
Sbjct 2506 EYTRPGYCVSLNPQWVLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLAT 2564
Query 3050 GGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIY 3109
++ +VV + ++F+ F Y+ V L+++++ +LC+ S L + V+Y
Sbjct 2565 MFLILVVVVLIFAMVIKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLY 2624
Query 3110 LYLTFYLTNDVSFLAHIQWMVMFTPLVPFWIT---IAYIICISTKHFYWFFSNYLKRRVV 3166
Y + + + + H + F +VP W+ + +II + T F W + R +
Sbjct 2625 CYASLVTSRNTVIIMHCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKL 2684
Query 3167 FNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTS 3225
++G F ++ AA TF++ ++KL +++ ++ YL+ Y + KY+SG
Sbjct 2685 YDGNEFVGNYDLAAKSTFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQD 2741
Query 3226 YREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTC 3285
Y +A LA AL+ + NSG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+
Sbjct 2742 YLQACRAWLAYALDQYRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSY 2801
Query 3286 GTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLIRKSNHNFLVQAGN-VQLRVIGH 3343
LNGLWL D +YCPRHV+ S D N D+L +NH F V + V L V+
Sbjct 2802 RGNNLNGLWLGDTIYCPRHVLGKFSGDQWN----DVLNLANNHEFEVTTQHGVTLNVVSR 2857
Query 3344 SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSF 3403
++ VL L+ AN +TPKYKF++ G +F++ Y G+ G+Y MR N TI+ SF
Sbjct 2858 RLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASF 2917
Query 3404 LNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTI 3463
L G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G FYG +VD + AQ D +
Sbjct 2918 LAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLV 2977
Query 3464 TVNVLAWLYAAVINGD-------RWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPL 3516
T N++AWLYAA+I+ +W L T +++D+N A + P + + L
Sbjct 2978 TNNIVAWLYAAIISVKESSFSLPKW-LESTTVSVDDYNKWAGDNGFTPFSTSTA--ITKL 3034
Query 3517 SAQTGIAVLDMCASLKELL--QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKR 3574
SA TG+ D+C L+ ++ + G ILG EDE TP V Q GV QS+ R
Sbjct 3035 SAITGV---DVCKLLRTIMVKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSFVR 3091
Query 3575 TIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKH 3631
+ W +L L L +V T L F++Y L A+ I+ + VKH
Sbjct 3092 KAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFT------VKH 3144
Query 3632 KHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRIMTWLDMV--DTSL-------- 3674
A++ FLLP+L TV A +Y + + V+ + W D V DT +
Sbjct 3145 VMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPLV 3204
Query 3675 --SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAI 3731
+ FK ++ C M + LL+L + ++T N LT + GN
Sbjct 3205 LYTAFKCVQGCYMNSFNTSLLMLYQFVKL----GFVIYTSSNTLTAYTE---GN------ 3251
Query 3732 SMWALII-----SVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFL 3786
W L +V +N S +F+ + +M + YC ++ L +M V C +
Sbjct 3252 --WELFFELVHTTVLANVSSNSLIGLFVFKCAKWM-LYYCNATYLNNYVLMAVM-VNC-I 3306
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G
Sbjct 3307 GWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQG 3366
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG + +ATVQ+K+SDVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E
Sbjct 3367 IGGDRVLPIATVQAKLSDVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGE 3426
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
+ ++ +L L + +D+++ C+++L LQ++ EFS +PSYA + A+ YE+
Sbjct 3427 CMDNLLGMLITLFCIDSTIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEK 3486
Query 3967 AVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKR 4022
+ + G ++ L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+R
Sbjct 3487 VLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRR 3546
Query 4023 AKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKN 4082
AK+ S++ +LF+ML+K+D++ LN + + A G VPL +P+ + KL +VIPD T+
Sbjct 3547 AKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVK 3606
Query 4083 TCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-----NSPNLAWPLIVTALRANSA- 4136
+G TY++ +W I V+DAD + + + N+AWPL V R
Sbjct 3607 CVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNK 3666
Query 4137 --VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
V LQNNEL P ++ +C AG Q C+ ++ YY G V A+ S +LK A
Sbjct 3667 VDVVLQNNELMPHGVKTKACVAGVDQAHCSVESK-CYYTNISGNSVVAAITSSNPNLKVA 3725
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
F G IY +L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+
Sbjct 3726 SFLNEAGN-QIYVDLDPPCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQS 3784
Query 4255 -GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
G+ TE +LS C+FAVD A Y Y+A+G QP+ NCVKML H G+G AIT P
Sbjct 3785 KGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPS 3844
Query 4314 ANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
DQ+S+GGAS CLYCR HI HP N G C KG +VQIPTT DPVGF L+N V
Sbjct 3845 PTPDQDSYGGASVCLYCRAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKV 3903
Query 4370 CTVCGMWKGYGCSCDQLREPM--LQSADAQS-----FLNRVCGVSAARLTPCGTGTSTDV 4422
CTVC W GYGC CD LR+P +QS S +LNRV G S ARL P +G DV
Sbjct 3904 CTVCQCWIGYGCQCDSLRQPKSSVQSVAGASDFDKNYLNRVRGSSEARLIPLASGCDPDV 3963
Query 4423 VYRAFDIYNDKVAGFAKFLKTNCCRFQE--KDEDDNL--IDSYFVVKRHTFSNYQHEETI 4478
V RAFD+ N + AG + LK NC RFQE ED NL +DSYFVVK+ T SNY+HE++
Sbjct 3964 VKRAFDVCNKESAGMFQNLKRNCARFQELRDTEDGNLEYLDSYFVVKQTTPSNYEHEKSC 4023
Query 4479 YNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEIL 4538
Y LK A HDFF F + + +ISRQRLTKYTM D YALRHFD +C+ LKEIL
Sbjct 4024 YEDLKS-EVTADHDFFVFNKN---IYNISRQRLTKYTMMDFCYALRHFDPKDCEVLKEIL 4079
Query 4539 VTYNCCDD---DYFNK-KDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIV 4594
VTY C +D +F + KDWYD +EN + A +G VR+ALL ++F + M G V
Sbjct 4080 VTYGCIEDYHPKWFEENKDWYDPIENSKYYVMLAKMGPIVRRALLNAIEFGNLMVEKGYV 4139
Query 4595 GVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLT 4654
GV+TLDNQDLNG +YDFGDF +T PG+GVPV D+YYS +MPI+ +T AL E + + D+
Sbjct 4140 GVITLDNQDLNGKFYDFGDFQKTAPGAGVPVFDTYYSYMMPIIAMTDALAPERYFEYDVH 4199
Query 4655 KPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFP 4714
K Y +DLLKYD+TEE+ +LF +YFKYWDQ YHPNC +C DDRC++HCANFN+LFST+ P
Sbjct 4200 KGYKSYDLLKYDYTEEKQELFQKYFKYWDQEYHPNCRDCSDDRCLIHCANFNILFSTLIP 4259
Query 4715 PTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHA 4774
TSFG L RK+FVDGVPF+ + GYH +ELGV+ NQD + S++ +L+ + DPA+
Sbjct 4260 QTSFGNLCRKVFVDGVPFIATCGYHSKELGVIMNQDNTMSFSKMGLSQLMQFVGDPALLV 4319
Query 4775 ASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFF 4834
+ N L+D RT+CFSV ALT+ + QTVKPG+FNKDFYDFA G FKEGSS+ LKHFF+
Sbjct 4320 GTSNNLVDLRTSCFSVCALTSGITHQTVKPGHFNKDFYDFAEKAGMFKEGSSIPLKHFFY 4379
Query 4835 AQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSA 4894
Q GNAAI+DYDYYRYN PTM DI QLLF +EV KYF+CY+GGCI A+QV+VNNLDKSA
Sbjct 4380 PQTGNAAINDYDYYRYNRPTMFDICQLLFCLEVTSKYFECYEGGCIPASQVVVNNLDKSA 4439
Query 4895 GFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSI 4954
G+PFNK+GKARLYY+ MS E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI
Sbjct 4440 GYPFNKFGKARLYYE-MSLEEQDQLFEITKKNVLPTITQMNLKYAISAKNRARTVAGVSI 4498
Query 4955 CSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKC 5014
STMTNRQFHQK+LKSI TR A+VVIGT+KFYGGW NML+ + VE+P LMGWDYPKC
Sbjct 4499 LSTMTNRQFHQKILKSIVNTRNASVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKC 4558
Query 5015 DRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSS 5074
DRAMPN+LRI ASLVLARKHT CCS S R YRL NECAQVLSE V+ G +YVKPGGTSS
Sbjct 4559 DRAMPNLLRIAASLVLARKHTNCCSWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSS 4618
Query 5075 GDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFV 5134
GDATTAYANSVFNI QA +ANV LLS I +++LQ+ LY+ +YR + D FV
Sbjct 4619 GDATTAYANSVFNIIQATSANVARLLSVITRDIVYDNIKSLQYELYQQVYRRVNFDPAFV 4678
Query 5135 NEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTE 5194
+FY+YL K+FS+MILSDD VVC+N+T A QGLVA I F+ VLYYQNNVFM+++KCW E
Sbjct 4679 EKFYSYLCKNFSLMILSDDGVVCYNNTLAKQGLVADISGFREVLYYQNNVFMADSKCWVE 4738
Query 5195 TDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSL 5254
DL KGPHEFCSQHTMLV+ + YLPYPDPSRILGA FVDD+ KT+ ++ER+++L
Sbjct 4739 PDLEKGPHEFCSQHTMLVEVDGEPKYLPYPDPSRILGACVFVDDVDKTEPVAVMERYIAL 4798
Query 5255 AIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYE 5314
AIDAYPL H N+EY VF + L YIRKL+ EL+ +ML YS ++ D S++WE EFYE
Sbjct 4799 AIDAYPLVHHENEEYKKVFFVLLAYIRKLYQELSQNMLMDYSFVMDIDKGSKFWEQEFYE 4858
Query 5315 AMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVC 5374
MY T LQ+ G CV+CNSQT LRCG CIR+PFLCCKCCYDHV+ T HK VLS+NPY+C
Sbjct 4859 NMYRAPTTLQSCGVCVVCNSQTILRCGNCIRKPFLCCKCCYDHVMHTDHKNVLSINPYIC 4918
Query 5375 NAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIA 5434
+ GC DVT+LYLGGMSY+C +HKP +S PL +NG VFG+Y+ C GS+NV DFN +A
Sbjct 4919 SQLGCGEADVTKLYLGGMSYFCGNHKPKLSIPLVSNGTVFGIYRANCAGSENVDDFNQLA 4978
Query 5435 TCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVG 5494
T +W+ YILAN C++ L+ FAAET+KATEE K + A VREV SDREL LSWE G
Sbjct 4979 TTNWSIVEPYILANRCSDSLRRFAAETVKATEELHKQQFASAEVREVFSDRELILSWEPG 5038
Query 5495 KPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSH 5554
K RPPLNRNYVFTGY T+ SKVQ+G++TFEKG+ D V Y+ T+T KL+VGD FVLTSH
Sbjct 5039 KTRPPLNRNYVFTGYHFTRTSKVQLGDFTFEKGEGKDVVYYKATSTAKLSVGDIFVLTSH 5098
Query 5555 TVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSH 5614
V+ L APTL PQ+ + R L P + + + F +N+ Y VG QK +T+QGPPG+GKSH
Sbjct 5099 NVVSLVAPTLCPQQTFSRFVNLRPNVMVPECFVNNIPLYHLVGKQKRTTVQGPPGSGKSH 5158
Query 5615 FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNS 5674
FAIGLA+Y+ SAR+V+TACSHAAVDALCEKA K+L +D C+RI+P R V+CF KFK N
Sbjct 5159 FAIGLAVYFSSARVVFTACSHAAVDALCEKAFKFLKVDDCTRIVPQRTTVDCFSKFKAND 5218
Query 5675 TLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRT 5734
T ++Y+F T+NALPE + DI++ DE+SM TNY+LS +N ++ ++ VY+GDPAQLPAPRT
Sbjct 5219 TGKKYIFSTINALPEVSCDILLVDEVSMLTNYELSFINGKINYQYVVYVGDPAQLPAPRT 5278
Query 5735 LLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ 5794
LL G+L P+ +N V LM + PD+FL C RCP EIVDTVS LVYD K A+ +S +
Sbjct 5279 LLN-GSLSPKDYNVVTNLMVCVKPDIFLAKCYRCPKEIVDTVSTLVYDGKFIANNPESRE 5337
Query 5795 CFKMFYKGV---ITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILG 5851
CFK+ + H+ SA N Q+ V++F+ RN WR+A+FISPYN+ N A ++LG
Sbjct 5338 CFKVIVNNGNSDVGHESGSAYNTTQLEFVKDFVCRNKQWREAIFISPYNAMNQRAYRMLG 5397
Query 5852 LPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRD-LYDKLQ 5910
L QTVDSSQGSEYDYVIF T ++ H+ N+NRFNVA+TRAK GIL +M RD LY L+
Sbjct 5398 LNVQTVDSSQGSEYDYVIFCVTADSQHALNINRFNVALTRAKRGILVVMRQRDELYSALK 5457
Query 5911 FTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGI 5970
FT L+ + +LQ TGLFK C+K +G+HP A T ++ +K + +
Sbjct 5458 FTELD----SETSLQG---TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNV 5510
Query 5971 P--KDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGT 6028
++TY+ LIS++GFKM+ V G NMFITR+EAIR+VR W+GFDVE HA +GT
Sbjct 5511 EAGSEITYKHLISLLGFKMSVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGT 5570
Query 6029 NLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVR 6088
NLP Q+GFSTG + V P G VDT +F V++K PPG+QF HL L PW+V+R
Sbjct 5571 NLPFQVGFSTGADFVVTPEGLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIR 5630
Query 6089 IKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDT 6148
+IVQML+D L N+SD VVFV W HG ELT+++YFVKIG E+ C C RAT F++ +
Sbjct 5631 PRIVQMLADNLCNVSDCVVFVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQA 5689
Query 6149 YACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVH 6208
YACW H +GFD+VYNP ++D+QQWG++GNLQ NHDL+C VHG+AHVAS DAIMTRCLA++
Sbjct 5690 YACWKHCLGFDFVYNPLLVDIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAIN 5749
Query 6209 ECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQ 6268
F + V+W + YP I +E ++N++CR +Q M + A + A K V++DIGNPK IKCV +
Sbjct 5750 NAFCQDVNWDLTYPHIANEDEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRR 5809
Query 6269 ADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDT 6328
DV ++FYD P + E Y Y H DKF DG+C+FWNCNVD YP NS+VCR+DT
Sbjct 5810 GDVNFRFYDKNPIVRNVKQFE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDT 5866
Query 6329 RVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDI 6388
R LS NLPGC+GGSLYVNKHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+
Sbjct 5867 RNLSVFNLPGCNGGSLYVNKHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ- 5925
Query 6389 DYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF 6448
D V L + CIT+CN+GGAVC+ HA Y ++ +YN ++AGF+ WV + + YNLW +F
Sbjct 5926 DLVSLATKDCITKCNIGGAVCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSF 5985
Query 6449 TRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFE 6508
+ LQS++N+A+N+ GH+D GE+P I + V+ GV+ +F N+TTLP +VAFE
Sbjct 5986 SALQSIDNIAYNMYKGGHYDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFE 6045
Query 6509 LWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETIC 6568
L+AKRNI+ +P +IL LGVD+ VIWDY P + +T+ VC+ TDI
Sbjct 6046 LYAKRNIRTLPNNRILKGLGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEPN------ 6099
Query 6569 APLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQ 6627
L V +D R G F A N VL++ K P + NG+ L A
Sbjct 6100 -GLVVLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---N 6154
Query 6628 FNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHI 6687
YK+V+G LP T TQ R+ + F+PRS +E DFL ++ + F+ERY + +HI
Sbjct 6155 LYVYKRVNGAFVTLPNTINTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHI 6213
Query 6688 VYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTV-KNYFITDAQTGSSKCVCSV 6746
+YG+ QLGGLH +IG+ + + + + DS V +NYF+ + GS K VC+V
Sbjct 6214 LYGEVDKPQLGGLHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVL-SDNGSYKQVCTV 6272
Query 6747 IDLLLDDFV----EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQA 6802
+DLLLDDF+ I+K + SKVV V+IDY I+FM W +DG ++T YP+LQS A
Sbjct 6273 VDLLLDDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQS--A 6329
Query 6803 WQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYN 6862
W G MP LYK+Q ++E C++ NYG TLP GI+MNVAKYTQLCQYL+ T+ VP+N
Sbjct 6330 WTCGYNMPELYKVQNCVMEPCNIPNYGVGITLPSGILMNVAKYTQLCQYLSKTTICVPHN 6389
Query 6863 MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW 6922
MRV+HFGAGSDKGVAPG+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC +T +K+
Sbjct 6390 MRVMHFGAGSDKGVAPGSTVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYNTEHKF 6449
Query 6923 DLIISDMY---DPKTKNV-TKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADL 6978
DL+ISDMY D K K+ N+ + F Y+ F++ LALGGS A+K+TE SW+ L
Sbjct 6450 DLVISDMYTDNDSKRKHEGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSWHEVL 6509
Query 6979 YKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPRE-QIDGYVMHANYIFWRNTNPIQL 7037
Y + AWWT F T VNASSSEAFLIG NYLG + ++ G +HANYIFWRN N +Q
Sbjct 6510 YDIAQDCAWWTMFCTAVNASSSEAFLIGVNYLGASEKVKVSGKTLHANYIFWRNCNYLQT 6569
Query 7038 SSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLV 7094
S+YS+FD++KF L+L+ T V++LK Q D++ +L+ G+L++R+ +SD V
Sbjct 6570 SAYSIFDVAKFDLRLKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 6626
Score = 68.2 bits (165), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 57/243 (23%), Positives = 107/243 (44%), Gaps = 15/243 (6%)
Query 1570 VFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRV 1629
++ T D + + V+ + GQ FG Y V + + + YV D ++
Sbjct 1180 IYLTEDGVKYRSIVLKPGDSLGQ-FGQVYAKNKIV--FTADDVEDKEILYVPTTDKSI-- 1234
Query 1630 EAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELK 1689
EYY ++ Y+ L +KW + ++W D NC++++A++ LQ +++
Sbjct 1235 --LEYYGLDAQKYV-IYLQTL--AQKWNVQYRDNFLILEWRDGNCWISSAIVLLQAAKIR 1289
Query 1690 FNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLN 1749
F L +A+ + G+ +F A A C VG+ D ++ L +H + D L
Sbjct 1290 FK-GFLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFSDANWLLANLAEHFDADYTNAFLK 1348
Query 1750 --VVCKTCGQQQTTLKGVEA-VMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVM 1806
V C CG + L+G+EA + + + FK TCG T +++ P+++
Sbjct 1349 KRVSC-NCGIKSYELRGLEACIQPVRATNLLHFKTQYSNCPTCGANNTDEVIEASLPYLL 1407
Query 1807 MSA 1809
+ A
Sbjct 1408 LFA 1410
Score = 53.9 bits (128), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 53/192 (28%), Positives = 87/192 (45%), Gaps = 20/192 (10%)
Query 985 QQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV---QTIEVNSFSGYLKLTDNVYIK 1041
++ V Q+DG++ Q + I V+PQ E + T E F Y ++ +
Sbjct 971 EEVVSQKDGAQIKQ----EPIQVVKPQREKKAKKFKVKPATCEKPKFLEYKTCVGDLTVV 1026
Query 1042 NADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGG 1101
A ++E K+ +VNAAN ++ HG GVA A+ +DY+ +GP +
Sbjct 1027 IAKALDEFKEF---CIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ--- 1080
Query 1102 SCVLSGHNLAKHCL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGADP 1158
V C+ +VVGP + L +AY+N V+ + P+LS GIFG D
Sbjct 1081 RLVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGVD- 1139
Query 1159 IHSLRVCVDTVR 1170
++ +D +R
Sbjct 1140 ---FKMSIDAMR 1148
>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep
PE=3 SV=1
Length=6629
Score = 4155 bits (10775), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2290/5157 (44%), Positives = 3139/5157 (61%), Gaps = 298/5157 (6%)
Query 2080 ANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIA 2139
A N +K+ +++G + ++ + KPN L R+ + A G + V + I
Sbjct 1626 AENFVKMGDKIGGVTMGLWRAEH----LNKPN-LERIFNIAKKAIVGSSVVTTQCGKLIG 1680
Query 2140 NYAKPFLNKVVSTTTNIVTRCLNRVC--------TNYMPYFF-TLLLQLCTFTRSTNSRI 2190
A +KV +T + +C P F TL+ L F +++ +
Sbjct 1681 KAATFIADKVGGGVVRNITDSIKGLCGITRGHFERKMSPQFLKTLMFFLFYFLKASVKSV 1740
Query 2191 KASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAAL 2250
AS T + K + ++ +I+WF+ S ++++ +
Sbjct 1741 VASYKTVLCKVVLATL----------------------LIVWFVYTS---NPVMFTGIRV 1775
Query 2251 GVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQIT 2310
+ L S C Y++ +S +V YC C VCL DSL Y +++
Sbjct 1776 ---LDFLFEGSLCGPYKDYGKDSFDVL--RYCADDFICRVCLHDKDSLHLYKHAYSVEQV 1830
Query 2311 ISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAIMQLFFSYFAVHFISNSWLMWLI 2368
A G + W Y++F F V G I Y + + NS ++
Sbjct 1831 YKD-----AASGFIFNWNWLYLVFLILFVKPVAGFVII-----CYCVKYLVLNSTVLQTG 1880
Query 2369 INLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVVDGCNSSTCMMCYKRNRATRVEC 2423
+ + + + + F + +Y W Y VH + C TC +C + R+ R E
Sbjct 1881 VCFLDWF-VQTVFSHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEV 1939
Query 2424 TTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINP 2483
+ +V G ++ +VY N G FCK HNW C NCD + +TF+S EVA +LS + KR + P
Sbjct 1940 SVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKP 1999
Query 2484 TDQSSYIVDSVTVKNGSIHLYFDKAGQ-KTYERHSLSHFVNLDNLR-ANNTKGSLPINVI 2541
T + ++VD + + ++L + A K ++ F D L+ A K +L I
Sbjct 2000 TAYAYHVVDEACLVDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQI 2059
Query 2542 VFDGKSKCEESSA------KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYV 2595
DG C SA K+A++YY+Q +C+PIL+LDQAL +
Sbjct 2060 SNDGFIVCNTQSAHALEEAKNAAIYYAQYLCKPILILDQALYEQL--------------- 2104
Query 2596 NTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVECL 2655
V K+++ + L+ +S+D + + + + S + ++ V+
Sbjct 2105 --------VVEPVSKSVIDKVCSILSSIISVDTAALNYKAGTLRDALLSITKDEEAVDMA 2156
Query 2656 KLSHQSDIEVTGDSCNNYMLTYN-KVENMTPRDLGACIDCSARHINAQVAKSHNIALIWN 2714
H D++ TGD N + +Y +TPRD G I+ A N +V + + +W
Sbjct 2157 IFCHNHDVDYTGDGFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAPPV--VWK 2214
Query 2715 VKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL--KGGKIVNN---W 2769
+ + LS+ K + SA K+ + F +T + +QV+ T K+ + K G IV+
Sbjct 2215 FSELIKLSDSCLKYLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKC 2274
Query 2770 LKQLIKVTLVF--LFVA---AIFYLITPVHVMSKHTDFSS--EIIGYKAIDGGVTRDIAS 2822
K K L+F LF A +Y+ + D +S + G+K ID GV R+I
Sbjct 2275 FKSYFKWLLIFYILFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVP 2334
Query 2823 TDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNG-DF 2881
DTCF+NK +FD ++ G Y N + CP++ AVI + G V G+PG + +G F
Sbjct 2335 EDTCFSNKFVNFDAFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMF 2390
Query 2882 LH---------FLPRVFSA--VGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPV 2930
+H ++P F+ VG YT +I F TS + +A C ++ AS P
Sbjct 2391 IHMTQTERKPWYIPTWFNREIVG---YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQ 2446
Query 2931 PYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTC 2989
YC++ N G++ + S+ P Y +G + P L V DS YCR C
Sbjct 2447 LYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQILHTPYVVKFVSDS-YCRGSVC 2505
Query 2990 ERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVA 3049
E + G CVS + +WVL ND Y S PGVFCG L+ +M + + +I +
Sbjct 2506 EYTRPGYCVSLNPQWVLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLAT 2564
Query 3050 GGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIY 3109
++ +VV + ++F+ F Y+ V L+++++ +LC+ S L + V+Y
Sbjct 2565 MFLILVVVVLIFAMVIKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLY 2624
Query 3110 LYLTFYLTNDVSFLAHIQWMVMFTPLVPFWIT---IAYIICISTKHFYWFFSNYLKRRVV 3166
Y + + + + H + F +VP W+ + +II + T F W + R +
Sbjct 2625 CYASLVTSRNTVIIMHCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKL 2684
Query 3167 FNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTS 3225
++G F ++ AA TF++ ++KL +++ ++ YL+ Y + KY+SG
Sbjct 2685 YDGNEFVGNYDLAAKSTFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQD 2741
Query 3226 YREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTC 3285
Y +A LA AL+ + NSG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+
Sbjct 2742 YLQACRAWLAYALDQYRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSY 2801
Query 3286 GTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLIRKSNHNFLVQAGN-VQLRVIGH 3343
LNGLWL D +YCPRHV+ S D N D+L +NH F V + V L V+
Sbjct 2802 RGNNLNGLWLGDTIYCPRHVLGKFSGDQWN----DVLNLANNHEFEVTTQHGVTLNVVSR 2857
Query 3344 SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSF 3403
++ VL L+ AN +TPKYKF++ G +F++ Y G+ G+Y MR N TI+ SF
Sbjct 2858 RLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASF 2917
Query 3404 LNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTI 3463
L G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G FYG +VD + AQ D +
Sbjct 2918 LAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLV 2977
Query 3464 TVNVLAWLYAAVINGD-------RWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPL 3516
T N++AWLYAA+I+ +W L T +++D+N A + P + + L
Sbjct 2978 TNNIVAWLYAAIISVKESSFSLPKW-LESTTVSVDDYNKWAGDNGFTPFSTSTA--ITKL 3034
Query 3517 SAQTGIAVLDMCASLKELL--QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKR 3574
SA TG+ D+C L+ ++ + G ILG EDE TP V Q GV QS+ R
Sbjct 3035 SAITGV---DVCKLLRTIMVKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSFVR 3091
Query 3575 TIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKH 3631
+ W +L L L +V T L F++Y L A+ I+ + VKH
Sbjct 3092 KAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFT------VKH 3144
Query 3632 KHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRIMTWLDMV--DTSL-------- 3674
A++ FLLP+L TV A +Y + + V+ + W D V DT +
Sbjct 3145 VMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPLV 3204
Query 3675 --SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAI 3731
+ FK ++ C M + LL+L + ++T N LT + GN
Sbjct 3205 LYTAFKCVQGCYMNSFNTSLLMLYQFVKL----GFVIYTSSNTLTAYTE---GN------ 3251
Query 3732 SMWALII-----SVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFL 3786
W L +V +N S +F+ + +M + YC ++ L +M V C +
Sbjct 3252 --WELFFELVHTTVLANVSSNSLIGLFVFKCAKWM-LYYCNATYLNNYVLMAVM-VNC-I 3306
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G
Sbjct 3307 GWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQG 3366
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG + +ATVQ+K+SDVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E
Sbjct 3367 IGGDRVLPIATVQAKLSDVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGE 3426
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
+ ++ +L L + +D+++ C+++L LQ++ EFS +PSYA + A+ YE+
Sbjct 3427 CMDNLLGMLITLFCIDSTIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEK 3486
Query 3967 AVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKR 4022
+ + G ++ L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+R
Sbjct 3487 VLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRR 3546
Query 4023 AKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKN 4082
AK+ S++ +LF+ML+K+D++ LN + + A G VPL +P+ + KL +VIPD T+
Sbjct 3547 AKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVK 3606
Query 4083 TCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-----NSPNLAWPLIVTALRANSA- 4136
+G TY++ +W I V+DAD + + + N+AWPL V R
Sbjct 3607 CVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNK 3666
Query 4137 --VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
V LQNNEL P ++ +C AG Q C+ ++ YY G V A+ S +LK A
Sbjct 3667 VDVVLQNNELMPHGVKTKACVAGVDQAHCSVESK-CYYTNISGNSVVAAITSSNPNLKVA 3725
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
F G IY +L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+
Sbjct 3726 SFLNEAGN-QIYVDLDPPCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQS 3784
Query 4255 -GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
G+ TE +LS C+FAVD A Y Y+A+G QP+ NCVKML H G+G AIT P
Sbjct 3785 KGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPS 3844
Query 4314 ANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
DQ+S+GGAS CLYCR HI HP N G C KG +VQIPTT DPVGF L+N V
Sbjct 3845 PTPDQDSYGGASVCLYCRAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKV 3903
Query 4370 CTVCGMWKGYGCSCDQLREPM--LQSADAQS-----FLNRVCGVSAARLTPCGTGTSTDV 4422
CTVC W GYGC CD LR+P +QS S +LNRV G S ARL P +G DV
Sbjct 3904 CTVCQCWIGYGCQCDSLRQPKSSVQSVAGASDFDKNYLNRVRGSSEARLIPLASGCDPDV 3963
Query 4423 VYRAFDIYNDKVAGFAKFLKTNCCRFQE--KDEDDNL--IDSYFVVKRHTFSNYQHEETI 4478
V RAFD+ N + AG + LK NC RFQE ED NL +DSYFVVK+ T SNY+HE++
Sbjct 3964 VKRAFDVCNKESAGMFQNLKRNCARFQELRDTEDGNLEYLDSYFVVKQTTPSNYEHEKSC 4023
Query 4479 YNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEIL 4538
Y LK A HDFF F + + +ISRQRLTKYTM D YALRHFD +C+ LKEIL
Sbjct 4024 YEDLKS-EVTADHDFFVFNKN---IYNISRQRLTKYTMMDFCYALRHFDPKDCEVLKEIL 4079
Query 4539 VTYNCCDD---DYFNK-KDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIV 4594
VTY C +D +F + KDWYD +EN + A +G VR+ALL ++F + M G V
Sbjct 4080 VTYGCIEDYHPKWFEENKDWYDPIENSKYYVMLAKMGPIVRRALLNAIEFGNLMVEKGYV 4139
Query 4595 GVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLT 4654
GV+TLDNQDLNG +YDFGDF +T PG+GVPV D+YYS +MPI+ +T AL E + + D+
Sbjct 4140 GVITLDNQDLNGKFYDFGDFQKTAPGAGVPVFDTYYSYMMPIIAMTDALAPERYFEYDVH 4199
Query 4655 KPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFP 4714
K Y +DLLKYD+TEE+ +LF +YFKYWDQ YHPNC +C DDRC++HCANFN+LFST+ P
Sbjct 4200 KGYKSYDLLKYDYTEEKQELFQKYFKYWDQEYHPNCRDCSDDRCLIHCANFNILFSTLIP 4259
Query 4715 PTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHA 4774
TSFG L RK+FVDGVPF+ + GYH +ELGV+ NQD + S++ +L+ + DPA+
Sbjct 4260 QTSFGNLCRKVFVDGVPFIATCGYHSKELGVIMNQDNTMSFSKMGLSQLMQFVGDPALLV 4319
Query 4775 ASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFF 4834
+ N L+D RT+CFSV ALT+ + QTVKPG+FNKDFYDFA G FKEGSS+ LKHFF+
Sbjct 4320 GTSNNLVDLRTSCFSVCALTSGITHQTVKPGHFNKDFYDFAEKAGMFKEGSSIPLKHFFY 4379
Query 4835 AQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSA 4894
Q GNAAI+DYDYYRYN PTM DI QLLF +EV KYF+CY+GGCI A+QV+VNNLDKSA
Sbjct 4380 PQTGNAAINDYDYYRYNRPTMFDICQLLFCLEVTSKYFECYEGGCIPASQVVVNNLDKSA 4439
Query 4895 GFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSI 4954
G+PFNK+GKARLYY+ MS E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI
Sbjct 4440 GYPFNKFGKARLYYE-MSLEEQDQLFEITKKNVLPTITQMNLKYAISAKNRARTVAGVSI 4498
Query 4955 CSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKC 5014
STMTNRQFHQK+LKSI TR A+VVIGT+KFYGGW NML+ + VE+P LMGWDYPKC
Sbjct 4499 LSTMTNRQFHQKILKSIVNTRNASVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKC 4558
Query 5015 DRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSS 5074
DRAMPN+LRI ASLVLARKHT CCS S R YRL NECAQVLSE V+ G +YVKPGGTSS
Sbjct 4559 DRAMPNLLRIAASLVLARKHTNCCSWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSS 4618
Query 5075 GDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFV 5134
GDATTAYANSVFNI QA +ANV LLS I +++LQ+ LY+ +YR + D FV
Sbjct 4619 GDATTAYANSVFNIIQATSANVARLLSVITRDIVYDNIKSLQYELYQQVYRRVNFDPAFV 4678
Query 5135 NEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTE 5194
+FY+YL K+FS+MILSDD VVC+N+T A QGLVA I F+ VLYYQNNVFM+++KCW E
Sbjct 4679 EKFYSYLCKNFSLMILSDDGVVCYNNTLAKQGLVADISGFREVLYYQNNVFMADSKCWVE 4738
Query 5195 TDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSL 5254
DL KGPHEFCSQHTMLV+ + YLPYPDPSRILGA FVDD+ KT+ ++ER+++L
Sbjct 4739 PDLEKGPHEFCSQHTMLVEVDGEPKYLPYPDPSRILGACVFVDDVDKTEPVAVMERYIAL 4798
Query 5255 AIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYE 5314
AIDAYPL H N+EY VF + L YIRKL+ EL+ +ML YS ++ D S++WE EFYE
Sbjct 4799 AIDAYPLVHHENEEYKKVFFVLLAYIRKLYQELSQNMLMDYSFVMDIDKGSKFWEQEFYE 4858
Query 5315 AMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVC 5374
MY T LQ+ G CV+CNSQT LRCG CIR+PFLCCKCCYDHV+ T HK VLS+NPY+C
Sbjct 4859 NMYRAPTTLQSCGVCVVCNSQTILRCGNCIRKPFLCCKCCYDHVMHTDHKNVLSINPYIC 4918
Query 5375 NAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIA 5434
+ GC DVT+LYLGGMSY+C +HKP +S PL +NG VFG+Y+ C GS+NV DFN +A
Sbjct 4919 SQLGCGEADVTKLYLGGMSYFCGNHKPKLSIPLVSNGTVFGIYRANCAGSENVDDFNQLA 4978
Query 5435 TCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVG 5494
T +W+ YILAN C++ L+ FAAET+KATEE K + A VREV SDREL LSWE G
Sbjct 4979 TTNWSIVEPYILANRCSDSLRRFAAETVKATEELHKQQFASAEVREVFSDRELILSWEPG 5038
Query 5495 KPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSH 5554
K RPPLNRNYVFTGY T+ SKVQ+G++TFEKG+ D V Y+ T+T KL+VGD FVLTSH
Sbjct 5039 KTRPPLNRNYVFTGYHFTRTSKVQLGDFTFEKGEGKDVVYYKATSTAKLSVGDIFVLTSH 5098
Query 5555 TVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSH 5614
V+ L APTL PQ+ + R L P + + + F +N+ Y VG QK +T+QGPPG+GKSH
Sbjct 5099 NVVSLVAPTLCPQQTFSRFVNLRPNVMVPECFVNNIPLYHLVGKQKRTTVQGPPGSGKSH 5158
Query 5615 FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNS 5674
FAIGLA+Y+ SAR+V+TACSHAAVDALCEKA K+L +D C+RI+P R V+CF KFK N
Sbjct 5159 FAIGLAVYFSSARVVFTACSHAAVDALCEKAFKFLKVDDCTRIVPQRTTVDCFSKFKAND 5218
Query 5675 TLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRT 5734
T ++Y+F T+NALPE + DI++ DE+SM TNY+LS +N ++ ++ VY+GDPAQLPAPRT
Sbjct 5219 TGKKYIFSTINALPEVSCDILLVDEVSMLTNYELSFINGKINYQYVVYVGDPAQLPAPRT 5278
Query 5735 LLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ 5794
LL G+L P+ +N V LM + PD+FL C RCP EIVDTVS LVYD K A+ +S +
Sbjct 5279 LLN-GSLSPKDYNVVTNLMVCVKPDIFLAKCYRCPKEIVDTVSTLVYDGKFIANNPESRE 5337
Query 5795 CFKMFYKGV---ITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILG 5851
CFK+ + H+ SA N Q+ V++F+ RN WR+A+FISPYN+ N A ++LG
Sbjct 5338 CFKVIVNNGNSDVGHESGSAYNTTQLEFVKDFVCRNKQWREAIFISPYNAMNQRAYRMLG 5397
Query 5852 LPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRD-LYDKLQ 5910
L QTVDSSQGSEYDYVIF T ++ H+ N+NRFNVA+TRAK GIL +M RD LY L+
Sbjct 5398 LNVQTVDSSQGSEYDYVIFCVTADSQHALNINRFNVALTRAKRGILVVMRQRDELYSALK 5457
Query 5911 FTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGI 5970
FT L+ + +LQ TGLFK C+K +G+HP A T ++ +K + +
Sbjct 5458 FTELD----SETSLQG---TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNV 5510
Query 5971 P--KDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGT 6028
++TY+ LIS++GFKM+ V G NMFITR+EAIR+VR W+GFDVE HA +GT
Sbjct 5511 EAGSEITYKHLISLLGFKMSVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGT 5570
Query 6029 NLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVR 6088
NLP Q+GFSTG + V P G VDT +F V++K PPG+QF HL L PW+V+R
Sbjct 5571 NLPFQVGFSTGADFVVTPEGLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIR 5630
Query 6089 IKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDT 6148
+IVQML+D L N+SD VVFV W HG ELT+++YFVKIG E+ C C RAT F++ +
Sbjct 5631 PRIVQMLADNLCNVSDCVVFVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQA 5689
Query 6149 YACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVH 6208
YACW H +GFD+VYNP ++D+QQWG++GNLQ NHDL+C VHG+AHVAS DAIMTRCLA++
Sbjct 5690 YACWKHCLGFDFVYNPLLVDIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAIN 5749
Query 6209 ECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQ 6268
F + V+W + YP I +E ++N++CR +Q M + A + A K V++DIGNPK IKCV +
Sbjct 5750 NAFCQDVNWDLTYPHIANEDEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRR 5809
Query 6269 ADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDT 6328
DV ++FYD P + E Y Y H DKF DG+C+FWNCNVD YP NS+VCR+DT
Sbjct 5810 GDVNFRFYDKNPIVRNVKQFE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDT 5866
Query 6329 RVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDI 6388
R LS NLPGC+GGSLYVNKHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+
Sbjct 5867 RNLSVFNLPGCNGGSLYVNKHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ- 5925
Query 6389 DYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF 6448
D V L + CIT+CN+GGAVC+ HA Y ++ +YN ++AGF+ WV + + YNLW +F
Sbjct 5926 DLVSLATKDCITKCNIGGAVCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSF 5985
Query 6449 TRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFE 6508
+ LQS++N+A+N+ GH+D GE+P I + V+ GV+ +F N+TTLP +VAFE
Sbjct 5986 SALQSIDNIAYNMYKGGHYDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFE 6045
Query 6509 LWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETIC 6568
L+AKRNI+ +P +IL LGVD+ VIWDY P + +T+ VC+ TDI
Sbjct 6046 LYAKRNIRTLPNNRILKGLGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEPN------ 6099
Query 6569 APLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQ 6627
L V +D R G F A N VL++ K P + NG+ L A
Sbjct 6100 -GLVVLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---N 6154
Query 6628 FNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHI 6687
YK+V+G LP T TQ R+ + F+PRS +E DFL ++ + F+ERY + +HI
Sbjct 6155 LYVYKRVNGAFVTLPNTINTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHI 6213
Query 6688 VYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTV-KNYFITDAQTGSSKCVCSV 6746
+YG+ QLGGLH +IG+ + + + + DS V +NYF+ + GS K VC+V
Sbjct 6214 LYGEVDKPQLGGLHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVL-SDNGSYKQVCTV 6272
Query 6747 IDLLLDDFV----EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQA 6802
+DLLLDDF+ I+K + SKVV V+IDY I+FM W +DG ++T YP+LQS A
Sbjct 6273 VDLLLDDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQS--A 6329
Query 6803 WQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYN 6862
W G MP LYK+Q ++E C++ NYG TLP GI+MNVAKYTQLCQYL T+ VP+N
Sbjct 6330 WTCGYNMPELYKVQNCVMEPCNIPNYGVGITLPSGILMNVAKYTQLCQYLLKTTICVPHN 6389
Query 6863 MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW 6922
MRV+HFGAGSDKGVAPG+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC +T +K+
Sbjct 6390 MRVMHFGAGSDKGVAPGSTVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYNTEHKF 6449
Query 6923 DLIISDMY---DPKTKNV-TKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADL 6978
DL+ISDMY D K K+ N+ + F Y+ F++ LALGGS A+K+TE SW+ L
Sbjct 6450 DLVISDMYTDNDSKRKHEGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSWHEVL 6509
Query 6979 YKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPRE-QIDGYVMHANYIFWRNTNPIQL 7037
Y + AWWT F T VNASSSEAFLIG NYLG + ++ G +HANYIFWRN N +Q
Sbjct 6510 YDIAQDCAWWTMFCTAVNASSSEAFLIGVNYLGASEKVKVSGKTLHANYIFWRNCNYLQT 6569
Query 7038 SSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLV 7094
S+YS+FD++KF L+L+ T V++LK Q D++ +L+ G+L++R+ +SD V
Sbjct 6570 SAYSIFDVAKFDLRLKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 6626
Score = 68.2 bits (165), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 57/243 (23%), Positives = 107/243 (44%), Gaps = 15/243 (6%)
Query 1570 VFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRV 1629
++ T D + + V+ + GQ FG Y V + + + YV D ++
Sbjct 1180 IYLTEDGVKYRSIVLKPGDSLGQ-FGQVYAKNKIV--FTADDVEDKEILYVPTTDKSI-- 1234
Query 1630 EAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELK 1689
EYY ++ Y+ L +KW + ++W D NC++++A++ LQ +++
Sbjct 1235 --LEYYGLDAQKYV-IYLQTL--AQKWNVQYRDNFLILEWRDGNCWISSAIVLLQAAKIR 1289
Query 1690 FNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLN 1749
F L +A+ + G+ +F A A C VG+ D ++ L +H + D L
Sbjct 1290 FK-GFLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFSDANWLLANLAEHFDADYTNAFLK 1348
Query 1750 --VVCKTCGQQQTTLKGVEA-VMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVM 1806
V C CG + L+G+EA + + + FK TCG T +++ P+++
Sbjct 1349 KRVSC-NCGIKSYELRGLEACIQPVRATNLLHFKTQYSNCPTCGANNTDEVIEASLPYLL 1407
Query 1807 MSA 1809
+ A
Sbjct 1408 LFA 1410
Score = 53.9 bits (128), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 53/192 (28%), Positives = 87/192 (45%), Gaps = 20/192 (10%)
Query 985 QQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV---QTIEVNSFSGYLKLTDNVYIK 1041
++ V Q+DG++ Q + I V+PQ E + T E F Y ++ +
Sbjct 971 EEVVSQKDGAQIKQ----EPIQVVKPQREKKAKKFKVKPATCEKPKFLEYKTCVGDLTVV 1026
Query 1042 NADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGG 1101
A ++E K+ +VNAAN ++ HG GVA A+ +DY+ +GP +
Sbjct 1027 IAKALDEFKEF---CIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ--- 1080
Query 1102 SCVLSGHNLAKHCL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGADP 1158
V C+ +VVGP + L +AY+N V+ + P+LS GIFG D
Sbjct 1081 RLVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGVD- 1139
Query 1159 IHSLRVCVDTVR 1170
++ +D +R
Sbjct 1140 ---FKMSIDAMR 1148
>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631
Score = 4152 bits (10769), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2260/4997 (45%), Positives = 3074/4997 (62%), Gaps = 258/4997 (5%)
Query 2229 IIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPC 2288
+I+WF+ S ++++ + + L S C Y + +S +V YC G C
Sbjct 1759 LIVWFIYTS---NPVVFTGIRV---LDFLFEGSLCGPYNDYGKDSFDVL--RYCAGDFTC 1810
Query 2289 SVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAI 2346
VCL DSL Y +++ A G+ W Y++F F V G I
Sbjct 1811 RVCLHDRDSLHLYKHAYSVEQIYKD-----AASGINFNWNWLYLVFLILFVKPVAGFVII 1865
Query 2347 MQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVV 2401
Y + + +S ++ + + + + + F + +Y W Y VH +
Sbjct 1866 -----CYCVKYLVLSSTVLQTGVGFLDWF-VKTVFTHFNFMGAGFYFWLFYKIYVQVHHI 1919
Query 2402 DGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAG 2461
C TC +C + R+ R E + +V G ++ +VY N G FCK HNW C NCD +
Sbjct 1920 LYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQ 1979
Query 2462 STFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKA-GQKTYERHSLSH 2520
+TF+S EVA +LS + KR + PT + ++V V + ++L + A K ++
Sbjct 1980 NTFMSPEVAGELSEKLKRHVKPTAYAYHVVYEACVVDDFVNLKYKAAIPGKDNASSAVKC 2039
Query 2521 FVNLDNLR-ANNTKGSLPINVIVFDGKSKCEESSA------KSASVYYSQLMCQPILLLD 2573
F D L+ A K +L I DG C SA K+A+VYY+Q +C+PIL+LD
Sbjct 2040 FSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSAHALEEAKNAAVYYAQYLCKPILILD 2099
Query 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
QAL + P+ K +++ + L+ +S+D +
Sbjct 2100 QAL---------------------YEQLIVEPVSK--SVIDKVCSILSNIISVDTAALNY 2136
Query 2634 ISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYN-KVENMTPRDLGACI 2692
+ + + S + ++ V+ H ++E TGD N + +Y + +TPRD G I
Sbjct 2137 KAGTLRDALLSITKDEEAVDMAIFCHNHEVEYTGDGFTNVIPSYGMDTDKLTPRDRGFLI 2196
Query 2693 DCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVN 2752
+ A N +V + + +W D + LS+ K + SA K+ F +T + +QV++
Sbjct 2197 NADASIANLRVKNAPPV--VWKFSDLIKLSDSCLKYLISATVKSGGRFFITKSGAKQVIS 2254
Query 2753 VVTTKIAL--KGGKIVNN---WLKQLIKVTLVF--LFVA---AIFYLITPVHVMSKHTDF 2802
T K+ + K G ++NN W K VF LF A +Y+ + D
Sbjct 2255 CHTQKLLVEKKAGGVINNTFKWFMSCFKWLFVFYILFTACCLGYYYMEMNKSFVHPMYDV 2314
Query 2803 SS--EIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITR 2860
+S + G+K ID GV R+I S D CF+NK +FD ++ G SY N+K CP++ VI
Sbjct 2315 NSTLHVEGFKVIDKGVIREIVSEDNCFSNKFVNFDAFW---GKSYENNKNCPIVTVVIDG 2371
Query 2861 EVGFVVPGLPGTILRTTNG-DFLH---------FLPRVFSA--VGNICYTPSKLIEYTDF 2908
+ G V G+PG + +G F+H ++P F+ VG YT +I F
Sbjct 2372 D-GTVAVGVPGFVSWVMDGVMFVHMTQTDRRPWYIPTWFNREIVG---YTQDSIITEGSF 2427
Query 2909 ATSACVLAAECTIFKDASGKPVPYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNT 2967
TS + +A C ++ AS P YC++ N G++ + S+ P Y +G + P
Sbjct 2428 YTSIALFSARC-LYLTASNTPQLYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQ 2486
Query 2968 YLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLL 3027
L V DS YCR CE ++ G CVS +WVL ND Y S PGVFCG L+
Sbjct 2487 ILHTPYIVKFVSDS-YCRGSVCEYTKPGYCVSLDSQWVLFNDEYISKPGVFCGSTVRELM 2545
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
NM + + +I + ++ +V+ + ++F+ F Y+ +V L++++
Sbjct 2546 FNMVSTFFTGVNP-NIYIQLATMFLILVVIVLIFAMVIKFQGVFKAYATIVFTIMLVWVI 2604
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWIT---IAY 3144
+ VLC+ S L + V+Y Y + + + + + H + F +VP W+ + +
Sbjct 2605 NAFVLCVHSYNSVLAVILLVLYCYASMVTSRNTAIIMHCWLVFTFGLIVPTWLACCYLGF 2664
Query 3145 IICISTKHFYWFFSNYLKRRVVFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQ 3203
I+ + T +W + R +++G F ++ AA TF++ ++KL +++ +
Sbjct 2665 ILYMYTPLVFWCYGTTKNTRKLYDGNEFVGNYDLAAKSTFVIRGTEFVKLTNEIG---DK 2721
Query 3204 YNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQ 3263
+ YL+ Y + KY+SG Y +A LA AL+ + NSG +V+Y PP+ SI + LQ
Sbjct 2722 FEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYALDQYRNSGVEVVYTPPRYSIGVSRLQ 2781
Query 3264 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 3323
+GF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ + D+L
Sbjct 2782 AGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVL---GKFSGDQWGDVLNL 2838
Query 3324 KSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 3382
+NH F V N V L V+ ++ VL L+ AN +TPKYKFV+ G +F++ Y
Sbjct 2839 ANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYG 2898
Query 3383 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3442
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G
Sbjct 2899 GTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMG 2958
Query 3443 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVIN-------GDRWFLNRFTTTLNDFNL 3495
FYG +VD + AQ D +T N++AWLYAA+I+ +W L T ++ D+N
Sbjct 2959 EFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKW-LESTTVSIEDYNR 3017
Query 3496 VAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRT--ILGSALLEDE 3553
A + P + + LSA TG+ D+C L+ ++ + ILG EDE
Sbjct 3018 WASDNGFTPFSTSTA--ITKLSAITGV---DVCKLLRTIMVKSAQWGSDPILGQYNFEDE 3072
Query 3554 FTPFDVVRQCSGVTFQSAVKRTIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENA 3610
TP V Q GV QS+ R + W +L L L +V T L F+++
Sbjct 3073 LTPESVFNQVGGVRLQSSFVRKAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVHAAV 3131
Query 3611 FLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRI 3663
L A+ I+ + VKH A++ FLLP+L TV A +Y + + V+ +
Sbjct 3132 ILLMAVLFISFT------VKHVMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFL 3185
Query 3664 MTWLDMV--DTSL----------SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWT 3710
W D V DT + + FK ++ C M + LL+L + ++T
Sbjct 3186 SQWYDPVVFDTMVPWMLLPLVLYTAFKCVQGCYMNSFNTSLLMLYQFMKL----GFVIYT 3241
Query 3711 LMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVE----YC 3766
N LT + GN W L + + L IVF C + YC
Sbjct 3242 SSNTLTAYTE---GN--------WELFFELVHTIVLANVSSNSLIGLIVFKCAKWMLYYC 3290
Query 3767 PIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQ 3826
+ L +M+ +G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM
Sbjct 3291 NATYFNNYVLMAVMVN--GIGWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLH 3348
Query 3827 GLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSK 3886
+ PPK + F NI + G+GG + +ATVQSK+SDVKCT+VVL+ +L +L VE++SK
Sbjct 3349 KVNPPKTVWEVFTTNILIQGIGGDRVLPIATVQSKLSDVKCTTVVLMQLLTKLNVEANSK 3408
Query 3887 LWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIAS 3946
+ A V+LHN IL + D E + ++ +L L + +D+ + C+++L LQ++
Sbjct 3409 MHAYLVELHNKILASDDVGECMDNLLGMLITLFCIDSTIDLGEYCDDILKRSTVLQSVTQ 3468
Query 3947 EFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE 4002
EFS +PSYA + A+ YE+ +A+ G ++ L +K+ N+AKS FDRD A+Q+KL+
Sbjct 3469 EFSHIPSYAEYERAKSIYEKVLADSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLD 3528
Query 4003 KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII 4062
MA++AMT MYK+AR D+RAK+ S++ +LF+ML+K+D++ LN + + A G VPL +
Sbjct 3529 SMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQANSGVVPLATV 3588
Query 4063 PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD----- 4117
P+ + KL +VIPD T+ +G TY++ +W I V DAD + +
Sbjct 3589 PIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDCVTDADGTELHPTSTGSGLTYCI 3648
Query 4118 NSPNLAWPLIVTALRANSA---VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNT 4174
+ N+AWPL V R V LQNNEL P ++ +C AG Q C+ ++ YY +
Sbjct 3649 SGDNIAWPLKVNLTRNGHNKVDVALQNNELMPHGVKTKACVAGVDQAHCSVESK-CYYTS 3707
Query 4175 TKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGL 4234
G V A+ S +LK A F G IY +L+PPC+F +V YLYFIK
Sbjct 3708 ISGSSVVAAITSSNPNLKVASFLNEAGN-QIYVDLDPPCKFGMKVGDKVEVVYLYFIKNT 3766
Query 4235 NNLNRGMVLGSLAATVRLQA-GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITN 4293
++ RGMVLG+++ V LQ+ G+ TE +LS C+FAVD A Y Y+A+G QP+ N
Sbjct 3767 RSIVRGMVLGAISNVVVLQSKGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGN 3826
Query 4294 CVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKY 4349
CVKML H G+G AIT P DQ+S+GGAS CLYCR HI HP N G C KG +
Sbjct 3827 CVKMLTVHNGSGFAITSKPSPTPDQDSYGGASVCLYCRAHIAHPGGAGNLDGRCQFKGSF 3886
Query 4350 VQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREP-------MLQSADAQSFLNR 4402
VQIPTT DPVGF L+N VCTVC W GYGC CD LR+P + S +++LNR
Sbjct 3887 VQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGCQCDSLRQPKPSVQSVAVASGFDKNYLNR 3945
Query 4403 VCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQE--KDEDDNL--I 4458
V G S ARL P G DVV RAFD+ N + AG + LK NC RFQE ED NL
Sbjct 3946 VRGSSEARLIPLANGCDPDVVKRAFDVCNKESAGMFQNLKRNCARFQEVRDTEDGNLEYC 4005
Query 4459 DSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMAD 4518
DSYFVVK+ T SNY+HE+ Y LK A HDFF F + + +ISRQRLTKYTM D
Sbjct 4006 DSYFVVKQTTPSNYEHEKACYEDLKS-EVTADHDFFVFNKN---IYNISRQRLTKYTMMD 4061
Query 4519 LVYALRHFDEGNCDTLKEILVTYNCCDD---DYFNK-KDWYDFVENPDILRVYANLGERV 4574
YALRHFD +C+ LKEILVTY C +D +F + KDWYD +ENP + A +G V
Sbjct 4062 FCYALRHFDPKDCEVLKEILVTYGCIEDYHPKWFEENKDWYDPIENPKYYAMLAKMGPIV 4121
Query 4575 RQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLM 4634
R+ALL ++F + M G VGV+TLDNQDLNG +YDFGDF +T PG+GVPV D+YYS +M
Sbjct 4122 RRALLNAIEFGNLMVEKGYVGVITLDNQDLNGKFYDFGDFQKTAPGAGVPVFDTYYSYMM 4181
Query 4635 PILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCL 4694
PI+ +T AL E + + D+ K Y +DLLKYD+TEE+ LF +YFKYWDQ YHPNC +C
Sbjct 4182 PIIAMTDALAPERYFEYDVHKGYKSYDLLKYDYTEEKQDLFQKYFKYWDQEYHPNCRDCS 4241
Query 4695 DDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLH 4754
DDRC++HCANFN+LFST+ P TSFG L RK+FVDGVPF+ + GYH +ELGV+ NQD +
Sbjct 4242 DDRCLIHCANFNILFSTLVPQTSFGNLCRKVFVDGVPFIATCGYHSKELGVIMNQDNTMS 4301
Query 4755 SSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDF 4814
S++ +L+ + DPA+ + N L+D RT+CFSV AL + + QTVKPG+FNKDFYDF
Sbjct 4302 FSKMGLSQLMQFVGDPALLVGTSNKLVDLRTSCFSVCALASGITHQTVKPGHFNKDFYDF 4361
Query 4815 AVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDC 4874
A G FKEGSS+ LKHFF+ Q GNAAI+DYDYYRYN PTM DIRQLLF +EV KYF+C
Sbjct 4362 AEKAGMFKEGSSIPLKHFFYPQTGNAAINDYDYYRYNRPTMFDIRQLLFCLEVTSKYFEC 4421
Query 4875 YDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQM 4934
Y+GGCI A+QV+VNNLDKSAG+PFNK+GKARLYY+ MS E+QD LF TK+NV+PTITQM
Sbjct 4422 YEGGCIPASQVVVNNLDKSAGYPFNKFGKARLYYE-MSLEEQDQLFESTKKNVLPTITQM 4480
Query 4935 NLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNML 4994
NLKYAISAKNRARTVAGVSI STMTNRQFHQK+LKSI TR A VVIGT+KFYGGW NML
Sbjct 4481 NLKYAISAKNRARTVAGVSILSTMTNRQFHQKILKSIVNTRNAPVVIGTTKFYGGWDNML 4540
Query 4995 KTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQV 5054
+ + VE+P LMGWDYPKCDRAMPN+LRI ASLVLARKHT CC+ S R YRL NECAQV
Sbjct 4541 RNLIQGVEDPILMGWDYPKCDRAMPNLLRIAASLVLARKHTNCCTWSERVYRLYNECAQV 4600
Query 5055 LSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRN 5114
LSE V+ G +YVKPGGTSSGDATTAYANSVFNI QA +ANV LLS I +++
Sbjct 4601 LSETVLATGGIYVKPGGTSSGDATTAYANSVFNIIQATSANVARLLSVITRDIVYDDIKS 4660
Query 5115 LQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNF 5174
LQ+ LY+ +YR + D FV +FY+YL K+FS+MILSDD VVC+N+T A QGLVA I F
Sbjct 4661 LQYELYQQVYRRVNFDPAFVEKFYSYLCKNFSLMILSDDGVVCYNNTLAKQGLVADISGF 4720
Query 5175 KSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGC 5234
+ VLYYQNNVFM+++KCW E DL KGPHEFCSQHTMLV+ + YLPYPDPSRIL A
Sbjct 4721 REVLYYQNNVFMADSKCWVEPDLEKGPHEFCSQHTMLVEVDGEPRYLPYPDPSRILCACV 4780
Query 5235 FVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDM 5294
FVDD+ KT+ ++ER+++LAIDAYPL H N+EY VF + L YIRKL+ EL+ +ML
Sbjct 4781 FVDDLDKTESVAVMERYIALAIDAYPLVHHENEEYKKVFFVLLSYIRKLYQELSQNMLMD 4840
Query 5295 YSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCC 5354
YS ++ D S++WE EFYE MY T LQ+ G CV+CNSQT LRCG CIR+PFLCCKCC
Sbjct 4841 YSFVMDIDKGSKFWEQEFYENMYRAPTTLQSCGVCVVCNSQTILRCGNCIRKPFLCCKCC 4900
Query 5355 YDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVF 5414
YDHV+ T HK VLS+NPY+C+ PGC DVT+LYLGGMSY+C +HKP +S PL +NG VF
Sbjct 4901 YDHVMHTDHKNVLSINPYICSQPGCGEADVTKLYLGGMSYFCGNHKPKLSIPLVSNGTVF 4960
Query 5415 GLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYG 5474
G+Y+ C GS+NV DFN +AT +W+ YILAN C + L+ FAAET+KATEE K +
Sbjct 4961 GIYRANCAGSENVDDFNQLATTNWSTVEPYILANRCVDSLRRFAAETVKATEELHKQQFA 5020
Query 5475 IATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVV 5534
A VREVLSDREL LSWE GK RPPLNRNYVFTG+ T+ SKVQ+G++TFEKG+ D V
Sbjct 5021 SAEVREVLSDRELILSWEPGKTRPPLNRNYVFTGFHFTRTSKVQLGDFTFEKGEGKDVVY 5080
Query 5535 YRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQ 5594
YR T+T KL+VGD FVLTSH V+ L APTL PQ+ + R L P + + F +N+ Y
Sbjct 5081 YRATSTAKLSVGDIFVLTSHNVVSLIAPTLCPQQTFSRFVNLRPNVMVPACFVNNIPLYH 5140
Query 5595 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5654
VG QK +T+QGPPG+GKSHFAIGLA Y+ +AR+V+TACSHAAVDALCEKA K+L +D C
Sbjct 5141 LVGKQKRTTVQGPPGSGKSHFAIGLAAYFSNARVVFTACSHAAVDALCEKAFKFLKVDDC 5200
Query 5655 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNAR 5714
+RI+P R ++CF KFK N T ++Y+F T+NALPE + DI++ DE+SM TNY+LS +N +
Sbjct 5201 TRIVPQRTTIDCFSKFKANDTGKKYIFSTINALPEVSCDILLVDEVSMLTNYELSFINGK 5260
Query 5715 LRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVD 5774
+ ++ VY+GDPAQLPAPRTLL G+L P+ +N V LM + PD+FL C RCP EIVD
Sbjct 5261 INYQYVVYVGDPAQLPAPRTLLN-GSLSPKDYNVVTNLMVCVKPDIFLAKCYRCPKEIVD 5319
Query 5775 TVSALVYDNKLKAHKDKSAQCFKMFYKGV---ITHDVSSAINRPQIGVVREFLTRNPAWR 5831
TVS LVYD K A+ +S QCFK+ + H+ SA N Q+ V++F+ RN WR
Sbjct 5320 TVSTLVYDGKFIANNPESRQCFKVIVNNGNSDVGHESGSAYNITQLEFVKDFVCRNKEWR 5379
Query 5832 KAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITR 5891
+A FISPYN+ N A ++LGL QTVDSSQGSEYDYVIF T ++ H+ N+NRFNVA+TR
Sbjct 5380 EATFISPYNAMNQRAYRMLGLNVQTVDSSQGSEYDYVIFCVTADSQHALNINRFNVALTR 5439
Query 5892 AKVGILCIMSDRD-LYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPT 5950
AK GIL +M RD LY L+F L+ +VA+LQ TGLFK C+K +G+HP A T
Sbjct 5440 AKRGILVVMRQRDELYSALKFIELD----SVASLQG---TGLFKICNKEFSGVHPAYAVT 5492
Query 5951 HLSVDTKFKTEGLCVDIPGIP--KDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHV 6008
++ +K + + ++TY+ LIS++GFKM+ V G NMFITR+EAIR+V
Sbjct 5493 TKALAATYKVNDELAALVNVEAGSEITYKHLISLLGFKMSVNVEGCHNMFITRDEAIRNV 5552
Query 6009 RAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPG 6068
R W+GFDVE HA +GTNLP Q+GFSTG + V P G VDT +F V++K PPG
Sbjct 5553 RGWVGFDVEATHACGTNIGTNLPFQVGFSTGADFVVTPEGLVDTSIGNNFEPVNSKAPPG 5612
Query 6069 DQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGP 6128
+QF HL L PW+VVR +IVQML+D L N+SD VVFV W HG ELT+++YFVKIG
Sbjct 5613 EQFNHLRALFKSAKPWHVVRPRIVQMLADNLCNVSDCVVFVTWCHGLELTTLRYFVKIGK 5672
Query 6129 ERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQV 6188
++ C C RAT F++ + YACW H +GFD+VYNP ++D+QQWG++GNLQ NHDL+C V
Sbjct 5673 DQVCS-CGSRATTFNSHTQAYACWKHCLGFDFVYNPLLVDIQQWGYSGNLQFNHDLHCNV 5731
Query 6189 HGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLA 6248
HG+AHVAS DAIMTRCLA++ F + V+W + YP I +E ++N++CR +Q M + A + A
Sbjct 5732 HGHAHVASADAIMTRCLAINNAFCQDVNWDLTYPHIANEDEVNSSCRYLQRMYLNACVDA 5791
Query 6249 DKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCL 6308
K V++DIGNPK IKCV + D+ ++FYD P + E Y Y H DKF DG+C+
Sbjct 5792 LKVNVVYDIGNPKGIKCVRRGDLNFRFYDKNPIVPNVKQFE---YDYNQHKDKFADGLCM 5848
Query 6309 FWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLP 6368
FWNCNVD YP NS+VCR+DTR LS NLPGC+GGSLYVNKHAFHTP FD+++F NLK +P
Sbjct 5849 FWNCNVDCYPDNSLVCRYDTRNLSVFNLPGCNGGSLYVNKHAFHTPKFDRTSFRNLKAMP 5908
Query 6369 FFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMIS 6428
FF+Y SPCE+ V+ D V L + CIT+CN+GGAVC+ HA Y ++ +YN ++
Sbjct 5909 FFFYDSSPCETIQLDGVAQ-DLVSLATKDCITKCNIGGAVCKKHAQMYADFVTSYNAAVT 5967
Query 6429 AGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVD 6488
AGF+ WV F+ YNLW +F+ LQS++N+A+N+ GH+D GE+P + + V+
Sbjct 5968 AGFTFWVTNNFNPYNLWKSFSALQSIDNIAYNMYKGGHYDAIAGEMPTIVTGDKVFVIDQ 6027
Query 6489 GVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHI 6548
GV+ +F N+T LP +VAFEL+AKRNI+ +P +IL LGVD+ VIWDY P +
Sbjct 6028 GVEKAVFFNQTILPTSVAFELYAKRNIRTLPNNRILKGLGVDVTNGFVIWDYTNQTPLYR 6087
Query 6549 STIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVG 6608
+T+ VC+ TDI L V +D R G F A N VL++ K
Sbjct 6088 NTVKVCAYTDIEPN-------GLIVLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEI 6139
Query 6609 PKQASL-NGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLE 6667
P + NG+ L A YK+V+G LP T TQ R+ + F+PRS +E DFL+
Sbjct 6140 PSNLLVQNGIPLKDGA---NLYVYKRVNGAFVTLPNTLNTQGRSYETFEPRSDVERDFLD 6196
Query 6668 LAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTV 6727
++ + F+E+Y E +HI+YG+ QLGGLH +IG+ + + + + DS V
Sbjct 6197 MSEESFVEKYGKE-LGLQHILYGEVDKPQLGGLHTVIGMCRLLRANKLNAKSVTNSDSDV 6255
Query 6728 -KNYFITDAQTGSSKCVCSVIDLLLDDFV----EIIKSQDLSVVSKVVKVTIDYTEISFM 6782
+NYF+ A GS K VC+V+DLLLDDF+ I+K + SKVV V+IDY I+FM
Sbjct 6256 MQNYFVL-ADNGSYKQVCTVVDLLLDDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFM 6313
Query 6783 LWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNV 6842
W +DG ++T YP+LQS AW G MP LYK+Q ++E C++ NYG LP GIMMNV
Sbjct 6314 AWFEDGIIKTCYPQLQS--AWTCGYNMPELYKVQNCVMEPCNIPNYGVGIALPSGIMMNV 6371
Query 6843 AKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFV 6902
AKYTQLCQYL+ T+ VP+NMRV+HFGAGSDKGVAPG+ VL+QWLP GTLLVD+D+ D+V
Sbjct 6372 AKYTQLCQYLSKTTMCVPHNMRVMHFGAGSDKGVAPGSTVLKQWLPEGTLLVDNDIVDYV 6431
Query 6903 SDADSTLIGDCATVHTANKWDLIISDMY---DPKTKNV-TKENDSKEGFFTYICGFIQQK 6958
SDA +++ DC T +K+DL+ISDMY D K K+ N+ + F Y+ F++
Sbjct 6432 SDAHVSVLSDCNKYKTEHKFDLVISDMYTDNDSKRKHEGVIANNGNDDVFIYLSSFLRNN 6491
Query 6959 LALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPRE-QI 7017
LALGGS A+K+TE SW+ LY + AWWT F T VNASSSEAFL+G NYLG + ++
Sbjct 6492 LALGGSFAVKVTETSWHEVLYDIAQDCAWWTMFCTAVNASSSEAFLVGVNYLGASEKVKV 6551
Query 7018 DGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGR 7077
G +HANYIFWRN N +Q S+YS+FD++KF L+L+ T V++LK Q D++ +L+ G+
Sbjct 6552 SGKTLHANYIFWRNCNYLQTSAYSIFDVAKFDLRLKATPVVNLKTEQKTDLVFNLIKCGK 6611
Query 7078 LIIRENNRVVISSDVLV 7094
L++R+ +SD V
Sbjct 6612 LLVRDVGNTSFTSDSFV 6628
Score = 72.4 bits (176), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 57/242 (24%), Positives = 108/242 (45%), Gaps = 13/242 (5%)
Query 1570 VFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRV 1629
++ T D + + V+ + GQ FG + A + + E K +P D +
Sbjct 1182 IYLTEDGVKYRSVVLKPGDSLGQ-FGQVF---ARNKVVFSADDVEDKEILFIPTTDKTIL 1237
Query 1630 EAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELK 1689
E Y+ D Y+ L +KW + ++W D NC++++A++ LQ +++
Sbjct 1238 E----YYGLDAQKYVTYLQTL--AQKWDVQYRDNFVILEWRDGNCWISSAIVLLQAAKIR 1291
Query 1690 FNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVL- 1748
F L +A+ + G+ +F A A CN VG+ D ++ L +H + D +L
Sbjct 1292 FK-GFLAEAWAKLLGGDPTDFVAWCYASCNAKVGDFSDANWLLANLAEHFDADYTNALLK 1350
Query 1749 NVVCKTCGQQQTTLKGVEA-VMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
V CG + L+G+EA + + + FK TCG +T +++ P++++
Sbjct 1351 KCVSCNCGVKSYELRGLEACIQPVRAPNLLHFKTQYSNCPTCGASSTDEVIEASLPYLLL 1410
Query 1808 SA 1809
A
Sbjct 1411 FA 1412
Score = 51.6 bits (122), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 50/180 (28%), Positives = 80/180 (44%), Gaps = 28/180 (16%)
Query 1009 QPQLEMELTPVVQ---------------TIEVNSFSGYLKLTDNVYIKNADIVEEAKKVK 1053
+PQ+E E T VV+ T E F Y ++ + A ++E K+
Sbjct 981 EPQVEQEPTLVVKAQREKKAKKFKVKPATCEKPKFLEYKTCVGDLAVVIAKALDEFKEF- 1039
Query 1054 PTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKH 1113
+VNAAN ++ HGGGVA A+ DY+ +GP + V
Sbjct 1040 --CIVNAANEHMSHGGGVAKAIADFCGPDFVEYCADYVKKHGPQQ---KLVTPSFVKGIQ 1094
Query 1114 CL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGADPIHSLRVCVDTVR 1170
C+ +VVGP + L +AY++ V+ + P+LS+GIFG D ++ +D +R
Sbjct 1095 CVNNVVGPRHGDSNLREKLVAAYKSVLVGGVVNYVVPVLSSGIFGVD----FKISIDAMR 1150
>sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus
HKU9 OX=694006 GN=1a PE=3 SV=1
Length=4248
Score = 2550 bits (6610), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1605/4497 (36%), Positives = 2393/4497 (53%), Gaps = 405/4497 (9%)
Query 28 VRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV--LPQLEQPYVFIKRSDARTAPHG-HV 84
V G+ +EE L A+Q L+ LV V + P + V I S G
Sbjct 29 VTGWDIPIEEALEYAKQQLRTPEPQLVFVPYYLSHAPGISGDRVVITDSIWYATNFGWQP 88
Query 85 MVELVAELEGIQYGRSGETLGVLVPH------VGEIPVAYRKVLLRKNGNKGAGGHSYGA 138
+ EL + +G++YGR G T GVL+P +G+I + RK G G +S
Sbjct 89 IRELAMDKDGVRYGRGG-THGVLLPMQDPSFIMGDIDIQIRKY--------GIGANSPPD 139
Query 139 DLKSFDLGDELGTD--PYEDFQENW-NTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
L +D + G D PY DF +N TK + ++ G DNN G
Sbjct 140 VLPLWDGFSDPGPDVGPYLDFPDNCCPTKPKAKRGGDVYLSDQYG-----FDNN-----G 189
Query 196 YPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPF 255
+E + LL K+ TL + L + G Y R+E Y+L +
Sbjct 190 ILVEPVMKLLGVI-KSDFTLEQLLAAL----GKY--------------RTEDGYDLPDGY 230
Query 256 ---EIKLAKK------------FDTFNGECPNFVFPLN--SIIKTIQPRVEKKKLDGFMG 298
IK+ +K P + +P + S+++ +P
Sbjct 231 VKVAIKVGRKAVPVLKQSIFTVVGVTEQLVPGYYYPFSTSSVVEHTKPTRGGPVGKTVEA 290
Query 299 RIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTE-NLTKEGATTC 357
+ S+Y N N +KC +C W + CG E LT ++C
Sbjct 291 VMLSLY---GTNNYNPATPVARLKCSYCDYYGWTPLKDIGTVNCLCGAEFQLT----SSC 343
Query 358 GYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRT-IAFGGCVFSYVGC 416
V+K P C + G++ I G RT ++FGG ++S +G
Sbjct 344 VDAESAGVIK---PGC----------VMLLDKSPGMRLI--PGNRTYVSFGGAIWSPIGK 388
Query 417 HNKCAYWVPRASANIGCNHTGVVGEG-SEGLNDNLLEILQKEKVNINIVGDFKLNEEIAI 475
N WVPRA + + H+G VG G + +N L+E L + I + D N A
Sbjct 389 VNGVTVWVPRAYSIVAGEHSGAVGSGDTVAINKELVEYLIE---GIRVDADTLDNPTCAT 445
Query 476 ILASFSASTSA----FVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILS 531
+A+ T A VE+++GL C K+ G E +
Sbjct 446 FIANLDCDTKAPVVHTVESLQGL-----------CLANKIMLGDKP---LPTDEFHPFIV 491
Query 532 PLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLA 591
L A+ + A ++ SRT E ++ VR ++ +Q+ ++ +
Sbjct 492 GL-AYHVQRACWYGALASRTFEAFRDFVRTEEER-------FAQFFGKVCAPI------- 536
Query 592 TNNLVVMAYITGGVVQLTSQWLTN------------IFGTVYEKLKPVLDWLEEKFKEGV 639
N V +AY TG V ++ + N + V + LKP+L+W+ +K +
Sbjct 537 -NGCVYLAYTTGRVTLFSAYQVLNTAIAKSKDAFGGVAAIVVDMLKPILEWVLKK----M 591
Query 640 EFLRDGW----EIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIII 695
+ W E + + +V G+ + + L+ ++ S+
Sbjct 592 SIAKGAWLPYAEGLLALFKAQFTVVKGKFQFLRASLNSKCHSLCDLLTTIMSKLLTSVKW 651
Query 696 GGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLM-PLKAPKEIIFLEGETLPTEVLTE 754
G K+ AL G + KG+ + + GLL+ P + E+ L+G+ LT+
Sbjct 652 AGCKVDALYTGTYYYFSRKGVLTEVQLCAKRLGLLLTPKQQKMEVEVLDGDFDAPVTLTD 711
Query 755 EVVLKTGDLQPLEQPTSEAVEAPLV-GTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTF 813
L+ + + + A + LV GT V + + + +D Y + V F
Sbjct 712 ---LELEECTGVLEEVFGASDVKLVKGTLVSLASKLFVRTEDGFLY-RYVKSGGVLGKAF 767
Query 814 TLKGGAPTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFAC 873
L+GG +KVTFGD+ V + +VN ++++ E +D +L++ + + VE GT++ + AC
Sbjct 768 RLRGGGVSKVTFGDEEVHTIPNTVTVNFSYDVCEGLDAILDKVMAPFQVEEGTKLEDLAC 827
Query 874 VVADAVIKTLQPV----SELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYP--P 927
VV AV + L + L P I+L+++ + +++ + E L MY S P
Sbjct 828 VVQKAVYERLSDLFSDCPAELRP--INLEDFLTSECFVYSKDYEKILMPEMYFSLEDAVP 885
Query 928 DEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQT 987
+DE D E+ ++ + ++ WL D
Sbjct 886 VDDEMVDDIED-----------------------------TVEQASDSDDQWLGD----- 911
Query 988 VGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVE 1047
+G+ED TI +V M TP GY K+ ++VYIK ADIV+
Sbjct 912 ----EGAEDCD----NTIQDVDVATSMT-TP----------CGYTKIAEHVYIKCADIVQ 952
Query 1048 EAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSG 1107
EA+ V+VNAANV L HGGGVAGALN+ATNNAMQ ES +YI NG L+ GG +LS
Sbjct 953 EARNYSYAVLVNAANVNLHHGGGVAGALNRATNNAMQKESSEYIKANGSLQPGGHVLLSS 1012
Query 1108 HNLAKH-CLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCV 1166
H LA H LHVVGP+ G+D+ LL + Y + + +L PL+SAGIFG SL V
Sbjct 1013 HGLASHGILHVVGPDKRLGQDLALLDAVYAAYTGFDSVLTPLVSAGIFGFTVEESLCSLV 1072
Query 1167 DTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRK 1226
V Y+ V+D+ LY++ +++ ++ + Q + I E E + S+ +
Sbjct 1073 KNVACTTYVVVYDRQLYERALATSFDVPGPQSSVQHVPAIDWAEA----VEVQESIVDQV 1128
Query 1227 QDDK--KIKACVEEVTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDITFLKKDAP 1284
+ + + L ET EN++ + PD +V+D++
Sbjct 1129 ETPSLGAVDTVDSNADSGLNETARSPENVVGSV-------PDD--VVADVE--------- 1170
Query 1285 YIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKVPTDNYITTYPGQGLNGYTVEEAKT 1344
V D+V++ V +KV D P + TVE+
Sbjct 1171 SCVRDLVRQVV----------------------KKVKRDK----RPPPIVPQQTVEQQPQ 1204
Query 1345 VLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQR 1404
+ +L ++S + M+ +E L+PV ++ A + ++R
Sbjct 1205 EISSPGDCNTVLVDVVS-----------MSFSAMVNFGKEKGLLIPVVIDYPAFLKVLKR 1253
Query 1405 KYKGIKIQEGVVDY-GARFYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAA 1463
+EG+ G FY Y+ + + LN L L+ +P G++ +G L +A
Sbjct 1254 ----FSPKEGLFSSNGYEFYGYSRDKPLHEVSKDLNSLGRPLIMIPFGFIVNGQTLAVSA 1309
Query 1464 RYMRSLKVPATVSVSSPDAVTAYNGYLT---SSSKTPEEHFIETISLAGSYKDWSYSGQS 1520
MR L VP TV V S +V Y Y S T + F+ I L G+ +DW +
Sbjct 1310 VSMRGLTVPHTVVVPSESSVPLYRAYFNGVFSGDTTAVQDFVVDILLNGA-RDWDVLQTT 1368
Query 1521 TQLGIE----FLKRGDKSVYYTSNPTTFHLDGEVI-TFDNLKTLLSLREVR------TIK 1569
+ + KRG+ + + + + + G+V+ F + + E + IK
Sbjct 1369 CTVDRKVYKTICKRGNTYLCF-DDTNLYAITGDVVLKFATVSKARAYLETKLCAPEPLIK 1427
Query 1570 VFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRV 1629
V TTVD IN T +V + +Y Q G + DG D + P + EG Y N + V
Sbjct 1428 VLTTVDGINYSTVLVSTAQSYRAQIGTVFCDGHDWSNKNPMPTDEGTHLYKQDNFSSAEV 1487
Query 1630 EAF-EYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIEL 1688
A EYY D + + R MS + W Y V+G + D+NCYL A+ LQ I++
Sbjct 1488 TAIREYYGVDDSNIIARAMSIRKTVQTWPYTVVDGRVLLAQRDSNCYLNVAISLLQDIDV 1547
Query 1689 KFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVL 1748
F+ P + AY + G +++A T G D +S + H + + +RV+
Sbjct 1548 SFSTPWVCRAYDALKGGNPLPMAEVLIALGKATPGVSDDAHMVLSAVLNHGTV-TARRVM 1606
Query 1749 NVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMS 1808
VC+ CG Q G +A + G++ + V + C CG+ A +Y+ +Q+SP+++MS
Sbjct 1607 QTVCEHCGVSQMVFTGTDACTFYGSVVLDDLYAPVSVVCQCGRPAIRYVSEQKSPWLLMS 1666
Query 1809 APPAQYELK-HGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
P Q L G + A + G GHY + + + D ++S+ K P TD+
Sbjct 1667 CTPTQVPLDTSGIWKTAIVFRGPVTAGHYMYAVNGTLISVYDANTRRRTSDLKLPATDIL 1726
Query 1868 YKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPNASFDN 1927
Y S+T+ K TY LDGV T IDP Y K+ + YFT PI++V P S+D
Sbjct 1727 YGPTSFTSDSKVETYYLDGVKRTTIDPDFSKYVKRGDYYFTTAPIEVVA-APKLVTSYDG 1785
Query 1928 FKF-VCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLL 1986
F C N + A+ N+ K +L +T +P++ GDVVAI + + G+ +
Sbjct 1786 FYLSSCQNPQLAESFNKAINATKTGPMKL-LTMYPNVAGDVVAISDDNVV-AHPYGSLHM 1843
Query 1987 HKPIVWHVNNATNKATYKPNTW-CIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLK 2045
KP+++ +PNTW + L ST V T N++DVL D
Sbjct 1844 GKPVLF---------VTRPNTWKKLVPLLSTVVVNTPNTYDVLAV------------DPL 1882
Query 2046 PVSEEVVENP-TIQKDVLECNVKTTEVVGDIILKPANNS-LKITEEVGHTDLMAAYVDN- 2102
PV+ E E P +++ + +K T V+ P N L +E TDL YV+
Sbjct 1883 PVNNETSEEPISVKAPIPLYGLKATMVLNGTTYVPGNKGHLLCLKEFTLTDLQTFYVEGV 1942
Query 2103 SSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT--NIVTRC 2160
+ K + LS+VLGL+ + VN + + YA L V+T+ +VTR
Sbjct 1943 QPFVLLKASHLSKVLGLRV--SDSSLHVNHLSKGVVYAYAATRLTTRVTTSLLGGLVTRS 2000
Query 2161 LNRV------------CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGK 2208
+ + C + F+ L ++ + +K S IA NT V
Sbjct 2001 VRKTADFVRSTNPGSKCVGLLCLFYQLFMRFWLLVKKP-PIVKVS--GIIAYNTGCGVTT 2057
Query 2209 FCLEASFNYLKSP----NFSKLINII-----IWFLL--LSVCLGSLIYSTAALGVLMSNL 2257
L NYL+S ++S+L+ ++ IWF+ L++C GV +S
Sbjct 2058 CVL----NYLRSRCGNISWSRLLKLLRYMLYIWFVWTCLTIC-----------GVWLSEP 2102
Query 2258 GMPSYCTGYRE--GYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFK 2315
PS T ++ G + + + +C++G+DSLD YP+L Q S
Sbjct 2103 YAPSLVTRFKYFLGIVMPCDYVLVNETGTGWLHHLCMAGMDSLD-YPALRMQQHRYGS-P 2160
Query 2316 WDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMA 2375
++ T ++ E F AY+L+T ++G+ A++ L Y + + NSWL+ + ++++
Sbjct 2161 YNYTYILMLLEAFFAYLLYTPALPIVGILAVLHLIVLYLPIP-LGNSWLVVFLYYIIRLV 2219
Query 2376 PISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFY 2435
P ++M+RMYI A + +K ++HV GCN+ C+MCYK+N A R+EC+T+VNGV+R FY
Sbjct 2220 PFTSMLRMYIVIAFLWLCYKGFLHVRYGCNNVACLMCYKKNVAKRIECSTVVNGVKRMFY 2279
Query 2436 VYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVT 2495
V ANGG FC HNWNCV+CDT+ STFI +VA DLS QFKRPI TD++ Y V SV
Sbjct 2280 VNANGGTHFCTKHNWNCVSCDTYTVDSTFICRQVALDLSAQFKRPIIHTDEAYYEVTSVE 2339
Query 2496 VKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLP-INVIVFDGKSKCEESSA 2554
V+NG ++ YF+ GQ++YER + F N+ L + KG+ P NV+VFD ++ EE++
Sbjct 2340 VRNGYVYCYFESDGQRSYERFPMDAFTNVSKLHYSELKGAAPAFNVLVFDATNRIEENAV 2399
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
K+A++YY+QL C+PILL+D+ +V VGD A +A MF+AY + +++ M+K+K L +
Sbjct 2400 KTAAIYYAQLACKPILLVDKRMVGVVGDDATIARAMFEAYAQNYLLKYSIAMDKVKHLYS 2459
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGFVD--SDVETKDVVECLKLSHQSDIEVTGDSCNN 2672
TA +++ +++++VL F+ + R D SDV+T D+V C++L HQ E T DS NN
Sbjct 2460 TALQQISSGMTVESVLKVFVGSTRAEAKDLESDVDTNDLVSCIRLCHQEGWEWTTDSWNN 2519
Query 2673 YMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSA 2732
+ TY K + ++ ++G + +A+++NA +AK + LIW DF+ LSE +R+Q++ A
Sbjct 2520 LVPTYIKQDTLSTLEVGQFMTANAKYVNANIAKGAAVNLIWRYADFIKLSESMRRQLKVA 2579
Query 2733 AKKNNLPFKLTCATTRQVVNVVTTKIALKGG-KIVNNWLKQLIKVTLVFLFVAAIFYLIT 2791
A+K L +T ++ + V + T + GG + + +W + LI V ++ + + ++ T
Sbjct 2580 ARKTGLNLLVTTSSLKADVPCMVTPFKIIGGHRRIVSWRRVLIHVFMLLVVLNPQWF--T 2637
Query 2792 PVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKAC 2851
P ++M ++ +K ID V RDI S D CFANK + F+ W+S R GSY N + C
Sbjct 2638 PWYIMRP---IEYNVVDFKVIDNAVIRDITSADQCFANKFSAFENWYSNRYGSYVNSRGC 2694
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRV---FSAVGNICYTPSKLIEYTDF 2908
P++ V++ VG +VPGLP LR LP V AVG++CYTP I Y F
Sbjct 2695 PMVVGVVSDIVGSLVPGLPARFLRVGT----TLLPLVNYGLGAVGSVCYTPHYAINYDVF 2750
Query 2909 ATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNT 2967
TSACVLAA CT+F ASG+ +PYC D +++ + Y+ L+P Y + S I+FP
Sbjct 2751 DTSACVLAATCTLFSSASGERMPYCADAALIQNASRYDMLKPHVMYPFYEHSGYIRFPEV 2810
Query 2968 YLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLL 3027
+ V +V T EYC+ G C+ SEAG+C+S RWV+NN Y+R GV+CG A +L
Sbjct 2811 -ISAGVHIVRTMAMEYCKVGRCDVSEAGLCMSLQPRWVVNNAYFRQQSGVYCGTSAFDLF 2869
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
NM P+ P+GA+DI+ SI+ G ++A+VV+ YY +RFRRAFG+YS V+ N L F++
Sbjct 2870 MNMLLPIFTPVGAVDITTSILMGALLAVVVSMSLYYLLRFRRAFGDYSGVIFTNILAFVL 2929
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIIC 3147
+ VLCL Y LP +Y++++LY T Y +D++ + H+ +++MF +VP W+T+ YI+
Sbjct 2930 NVIVLCLEGPYPMLPSIYAMVFLYATCYFGSDIACMMHVSFLIMFAGVVPLWVTVLYIVV 2989
Query 3148 ISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRY 3207
+ ++H WF S KR V ++F +F++AAL TF+L+KE++L+L+ ++ Y +Y
Sbjct 2990 VLSRHILWFASLCTKRTVQVGDLAFHSFQDAALQTFMLDKEVFLRLKREI--SSDAYFKY 3047
Query 3208 LALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFR 3267
LA+YNKYKY+SG MDT +YREAAC HL AL +SN G D +YQPP+ S+ SA LQ+G
Sbjct 3048 LAMYNKYKYYSGPMDTAAYREAACSHLVMALEKYSNGGGDTIYQPPRCSVASAALQAGLT 3107
Query 3268 KMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNH 3327
+MA PSG VE C+V+V G+ TLNG+WLD+ V CPRHV+C+ +++ NP+Y L +R +N+
Sbjct 3108 RMAHPSGLVEPCLVKVNYGSMTLNGIWLDNFVICPRHVMCSRDELANPDYPRLSMRAANY 3167
Query 3328 NFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSG 3387
+F V +RVIGH+M+ +LKL VD NPKTP Y F+R+ GQ S+LACY+G P+G
Sbjct 3168 DFHVSQNGHNIRVIGHTMEGSLLKLTVDVNNPKTPAYSFIRVSTGQAMSLLACYDGLPTG 3227
Query 3388 VYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGP 3447
VY C +R N T++ SFL GSCGS GF ++ V FCY+H +ELP G H GTD G FYGP
Sbjct 3228 VYTCTLRSNGTMRASFLCGSCGSPGFVMNGKEVQFCYLHQLELPNGTHTGTDFSGVFYGP 3287
Query 3448 FVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQ 3507
F D+Q Q A D TITVNVLAWLYAAV++G+ WFL + + + +FN A+KY + +T
Sbjct 3288 FEDKQVPQLAAPDCTITVNVLAWLYAAVLSGENWFLTKSSISPAEFNNCAVKYMCQSVTS 3347
Query 3508 DHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVT 3567
+ + +L PL+A+TGI+V M ++LK LL G GRTI+GS LEDE TP+D+ RQ GV
Sbjct 3348 ESLQVLQPLAAKTGISVERMLSALKVLLSAGFCGRTIMGSCSLEDEHTPYDIGRQMLGVK 3407
Query 3568 FQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMM 3627
Q + + T W + + ++L+L+Q QW+ L LP + F +
Sbjct 3408 LQGKFQSMFRWTLQWFAIIFVLTILILLQLAQWTFVGALPFTLLLPLIGFVAVCVGFVSL 3467
Query 3628 FVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYAS 3687
+KHKH +L ++LLP AY+N Y P +++ + V+ D +
Sbjct 3468 LIKHKHTYLTVYLLPVAMVTAYYNFQYTPEGVQGYLLSLYNYVNPGRIDVIGTDLLTMLI 3527
Query 3688 AVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGV 3747
V L++ R V D R+W + + +Y + G+A AIS ++SV +NY+GV
Sbjct 3528 ISVACTLLSVRMVRTDAYSRIWYVCTAVGWLYNCWTGSADTVAISYLTFMVSVFTNYTGV 3587
Query 3748 VTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
++ A+ +V++ P + +C+++ Y +GY CTCYFG+F L+NR FR T
Sbjct 3588 ACASLYAAQFMVWVLKFLDPTILLLYGRFRCVLVCYLLVGYLCTCYFGVFNLINRLFRCT 3647
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
LG Y+Y+VS+QE RYMNS GLLPP NS A LNIKL G+GG P +V+T+QS M+D+KC
Sbjct 3648 LGNYEYVVSSQELRYMNSHGLLPPTNSWQALMLNIKLAGIGGIPIYRVSTIQSNMTDLKC 3707
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDI 3927
TSVVLLSVLQQLRVESSSKLWA CV+LHN+IL + TEAFE VSLLSVLLS+ GA+++
Sbjct 3708 TSVVLLSVLQQLRVESSSKLWALCVKLHNEILASNSPTEAFEAFVSLLSVLLSLPGAINL 3767
Query 3928 NKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVA 3987
++LC +L+N + LQA+ASEFS+L SY + AQ+AY+ AVA G + LKK++NVA
Sbjct 3768 DELCSSILENNSVLQAVASEFSNLSSYVDYENAQKAYDTAVATGAPASTVNALKKAMNVA 3827
Query 3988 KSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNN 4047
KS D+D A RKLE+M++ AMT MYKQAR+ED+R+KVT+AMQTMLF M+R+LD+DAL+N
Sbjct 3828 KSVLDKDVATTRKLERMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSN 3887
Query 4048 IINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSK 4107
I+NNAR+G VPL +IP T A KL++V+PD++ Y T T TYA + W++ QV DAD K
Sbjct 3888 ILNNARNGVVPLGVIPRTAANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGK 3947
Query 4108 IVQLSEISMDNSPNLAWPLIVTALR--ANSAVKLQNNELSPVALRQMSCAAGTTQTACTD 4165
V ++I+ +NS NLAWPL+VTA R A S VKLQNNEL P +++M+ AG +QTAC
Sbjct 3948 TVNATDITRENSVNLAWPLVVTAQRQQATSPVKLQNNELMPQTVKRMNVVAGVSQTACVT 4007
Query 4166 DNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKV 4225
D A+AYYN TK GR V+A+L+D L +A+ KS G G + ELEPPC+F+ DTPKGP +
Sbjct 4008 D-AVAYYNATKEGRHVMAILADTDGLAFAKVEKSTGDGFVILELEPPCKFMVDTPKGPAL 4066
Query 4226 KYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLA 4285
KYLYF KGL NL RG VLG+LA TVRL AG+ATEV +NS++LS C+F+VD YKDYL
Sbjct 4067 KYLYFTKGLKNLCRGTVLGTLACTVRLHAGSATEVASNSSILSLCSFSVDPEATYKDYLD 4126
Query 4286 SGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDL 4345
+GG PI NCVKML HTGTG AIT P+AN+DQESFGGASCCLYCRCHI+HP G C
Sbjct 4127 NGGSPIGNCVKMLTPHTGTGLAITAKPDANIDQESFGGASCCLYCRCHIEHPGASGVCKY 4186
Query 4346 KGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNR 4402
KGK+VQIP NDP+GF ++N VC VC MW+GYGC C LRE LQ+ D + FLN
Sbjct 4187 KGKFVQIPLVGVNDPIGFCIRNVVCAVCNMWQGYGCPCSSLREINLQARD-ECFLNE 4242
>sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respiratory
syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=1a PE=1 SV=1
Length=4391
Score = 2192 bits (5680), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1249/3281 (38%), Positives = 1852/3281 (56%), Gaps = 187/3281 (6%)
Query 1259 INGNLHPDSATLVSDIDITFLKKDAPYIVGD-VVQEGVLTA-----VVIPTKKAGGTTEM 1312
I G ++ S V ++ P VGD V+ +G A VV P +A +
Sbjct 1156 IAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSL 1215
Query 1313 LAK---ALRKVPTDNYITTYPGQGLNG--------YTVEEAKTVLKKCKSAFYILPSIIS 1361
L+K A+ P +T G+ G Y + EAKT + ++ + S+
Sbjct 1216 LSKCYKAMNAYPL--VVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTI 1273
Query 1362 NEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGAR 1421
+ + L LR + A++ + VC + A ++ K + VD G +
Sbjct 1274 VDIPQSLTFSYDGLRGAIRKAKDYGFTVFVCTDNSANTKVLRNKGVDYTKKFLTVD-GVQ 1332
Query 1422 FYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPD 1481
+Y YTSK T+ ++ N + +++MPLGYV+HGL+L +A +R + VP +++ +
Sbjct 1333 YYCYTSKDTLDDILQQANK-SVGIISMPLGYVSHGLDLIQAGSVVRRVNVPYVCLLANKE 1391
Query 1482 AVTAYNGYLTSSSK--TPEEHFIETISLAGSYKDWSYSG-----QSTQLGIEFLKRGDKS 1534
L S P E FI+ + G Y W Q +L + L D++
Sbjct 1392 Q----EAILMSEDVKLNPSEDFIKHVRTNGGYNSWHLVEGELLVQDLRLN-KLLHWSDQT 1446
Query 1535 V-------YYTSNPTTFHLDGEVITFDNLKTLLSLREVR--TIKVFTTVDNINLHTQVVD 1585
+ Y N T F + T + L R + TI+V TVD +N T V++
Sbjct 1447 ICYKDSVFYVVKNSTAFPFE----TLSACRAYLDSRTTQQLTIEVLVTVDGVNFRTVVLN 1502
Query 1586 MSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAF-EYYHTTDPSFLG 1644
TY Q G + +GAD++ P G + Y+ N +A E Y DP+FL
Sbjct 1503 NKNTYRSQLGCVFFNGADISDTIPDEKQNGHSLYLADNLTADETKALKELYGPVDPTFLH 1562
Query 1645 RYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQI-ELKFNPPALQDAYYRAR 1703
R+ S KWK + + S+K +DNNCYL ++TL + ++KF PALQ A+ + +
Sbjct 1563 RFYSLKAAVHKWKMVVCDKVRSLKLSDNNCYLNAVIMTLDLLKDIKFVIPALQHAFMKHK 1622
Query 1704 AGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLD-SCKRVLNVVCKTCGQQQTTL 1762
G++ +F ALI+AY N T G D + + A L S + V C CG + L
Sbjct 1623 GGDSTDFIALIMAYGNCTFGAPDDASRLLHTVLAKAELCCSARMVWREWCNVCGIKDVVL 1682
Query 1763 KGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGT-- 1820
+G++A Y+G + E + + C CG + + +V+ +P++++S P + + T
Sbjct 1683 QGLKACCYVGVQTVEDLRARMTYVCQCGGERHRQIVEHTTPWLLLSGTPNEKLVTTSTAP 1742
Query 1821 -FTCASEYTG-NYQCGHYKHITSKETLYC-IDGALLTKSSEYKGPITDVFYKENSYTTTI 1877
F + + G GHY H K L D ++K+S++K +TDV + Y++
Sbjct 1743 DFVAFNVFQGIETAVGHYVHARLKGGLILKFDSGTVSKTSDWKCKVTDVLFPGQKYSSDC 1802
Query 1878 KPVTYKLDGVVCTEIDPKLDNYYKKDNSYFT-EQPIDLVPNQPYPNASFDNFKFVCDNIK 1936
V Y LDG TE+DP L +Y KD YFT E P+ P + + N V + +
Sbjct 1803 NVVRYSLDGNFRTEVDPDLSAFYVKDGKYFTSEPPVTYSPATILAGSVYTNSCLVSSDGQ 1862
Query 1937 FADD-----LNQLTGY--KKPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKP 1989
D N L G+ KP +++ +F P +GDV+ ++ Y P +K GA KP
Sbjct 1863 PGGDAISLSFNNLLGFDSSKPVTKKYTYSFLPKEDGDVLLAEFDTYDPIYKNGAMYKGKP 1922
Query 1990 IVWHVNNATNKATY-----KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDL 2044
I+W NKA+Y K N +R ++ P+E N F L E
Sbjct 1923 ILW-----VNKASYDTNLNKFNRASLRQIFDVAPIELENKFTPLSVEST----------- 1966
Query 2045 KPVSEEVVENPTIQKD--VLECNVKTTEVVGDIILKPANNS-LKITEEVGHTDLMAAYVD 2101
PV V+ +Q++ +++C V D + A++S + E + DL YVD
Sbjct 1967 -PVEPPTVDVVALQQEMTIVKCKGLNKPFVKDNVSFVADDSGTPVVEYLSKEDLHTLYVD 2025
Query 2102 -NSSLTIKKPNELSRVLGLKTLATHGL---AAVNSVPWDTIANYAKPFLNK----VVSTT 2153
+ + K N LS +L L T+ + + AA S+ + F K T
Sbjct 2026 PKYQVIVLKDNVLSSMLRLHTVESGDINVVAASGSLTRKVKLLFRASFYFKEFATRTFTA 2085
Query 2154 TNIVTRCLNRV-------------CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTT--- 2197
T V C+ V C +++ F L L + ++ + +K S T
Sbjct 2086 TTAVGSCIKSVVRHLGVTKGILTGCFSFVKMLFMLPLAYFSDSKLGTTEVKVSALKTAGV 2145
Query 2198 IAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSN- 2256
+ N VK ++ S + L+ ++ + +++ V L S+ + VL S+
Sbjct 2146 VTGNVVKQCCTAAVDLSMDKLRRVDWKSTLRLLLMLCTTMVLLSSVYHLYVFNQVLSSDV 2205
Query 2257 ------------------LGMPSYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDS 2297
LG+ S C G Y + + + T+C S C+ CL DS
Sbjct 2206 MFEDAQGLKKFYKEVRAYLGISSACDGLASAY-RANSFDVPTFCANRSAMCNWCLISQDS 2264
Query 2298 LDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVH 2357
+ YP+L+ +Q +S + ++ E LAY+L+T F L LA + FF+ ++
Sbjct 2265 ITHYPALKMVQTHLSHYVLNIDWLWFAFETGLAYMLYTSAFNWLLLAGTLHYFFAQTSIF 2324
Query 2358 FISNSW------LMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMM 2411
S+ WL ++ P++ +VRMY A + + K Y HV++GC + C++
Sbjct 2325 VDWRSYNYAVSSAFWLFTHI----PMAGLVRMYNLLACLWLLRKFYQHVINGCKDTACLL 2380
Query 2412 CYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVAR 2471
CYKRNR TRVE +T+V G +R+FY+ ANGG FC+ HNWNCV+CDT G+TFI +EVA
Sbjct 2381 CYKRNRLTRVEASTVVCGGKRTFYITANGGISFCRRHNWNCVDCDTAGVGNTFICEEVAN 2440
Query 2472 DLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLR--- 2528
DL+ +RPIN TD+S Y VDSVTVK + + + GQ YER L F NLD L+
Sbjct 2441 DLTTALRRPINATDRSHYYVDSVTVKETVVQFNYRRDGQPFYERFPLCAFTNLDKLKFKE 2500
Query 2529 -ANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVA 2587
T G N I++D + +ES A+SA VYYSQ++C+ ILL+D +LV+ VGDS+E+A
Sbjct 2501 VCKTTTGIPEYNFIIYDSSDRGQESLARSACVYYSQVLCKSILLVDSSLVTSVGDSSEIA 2560
Query 2588 VKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDV 2646
KMFD++VN+F S +NV +KL+ L++TA + + + +VL+TFI AAR V+SDV
Sbjct 2561 TKMFDSFVNSFVSLYNVTRDKLEKLISTARDGVRRGDNFHSVLTTFIDAARGPAGVESDV 2620
Query 2647 ETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKS 2706
ET ++V+ ++ +H+ DI++T +S NNY+ +Y K ++++ DLG+ IDC+A +N V ++
Sbjct 2621 ETNEIVDSVQYAHKHDIQITNESYNNYVPSYVKPDSVSTSDLGSLIDCNAASVNQIVLRN 2680
Query 2707 HNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIV 2766
N A IWN +M LS+ L++QIR A +K NL F+LT + R N+++ + KIV
Sbjct 2681 SNGACIWNAAAYMKLSDALKRQIRIACRKCNLAFRLTTSKLRANDNILSVR--FTANKIV 2738
Query 2767 NN---W--------LKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGG 2815
W LK + T++ A + YL P M + I+ +K +D G
Sbjct 2739 GGAPTWFNALRDFTLKGYVLATIIVFLCAVLMYLCLPTFSMVPVEFYEDRILDFKVLDNG 2798
Query 2816 VTRDIASTDTCFANKHADFDTWFSQR-GGSYTNDKACPLIAAVITREVGFVVPGLPGTIL 2874
+ RD+ D CFANKH F W+ + GG Y N CPL AVI G +P +P T L
Sbjct 2799 IIRDVNPDDKCFANKHRSFTQWYHEHVGGVYDNSITCPLTVAVIAGVAGARIPDVP-TTL 2857
Query 2875 RTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCY 2934
N + F+ RVF+ G++CYTP I Y F+ S C+L +ECT+F+DA G+ PYC+
Sbjct 2858 AWVNNQIIFFVSRVFANTGSVCYTPIDEIPYKSFSDSGCILPSECTMFRDAEGRMTPYCH 2917
Query 2935 DTNVLEGSVAYESLRPDTRYVLMDGSI-IQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
D VL G+ AY +RP RY L DG++ I+FP E ++R+ T ++YCR G+CE ++
Sbjct 2918 DPTVLPGAFAYSQMRPHVRYDLYDGNMFIKFPEVVFESTLRITRTLSTQYCRFGSCEYAQ 2977
Query 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
GVC++T+G W + ND++ + PGV+CG D ++++ + L QPI ++ S+V G +
Sbjct 2978 EGVCITTNGSWAIFNDHHLNRPGVYCGSDFIDIVRRLAVSLFQPITYFQLTTSLVLGIGL 3037
Query 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
+T L YY + +RAF +Y+ + +++ +C Y+ +Y Y T
Sbjct 3038 CAFLTLLFYYINKVKRAFADYTQCAVIAVVAAVLNSLCICFVASIPLCIVPYTALYYYAT 3097
Query 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV-VF-NGVS 3171
FY TN+ +F+ H+ W +MF P+VP W+T Y + + +HF+W + + K+ V VF +G
Sbjct 3098 FYFTNEPAFIMHVSWYIMFGPIVPIWMTCVYTVAMCFRHFFWVLAYFSKKHVEVFTDGKL 3157
Query 3172 FSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAAC 3231
+F++AA F++NK+ Y LR+ L Y+R+L L+NKYKYFSGAM+T +YREAA
Sbjct 3158 NCSFQDAASNIFVINKDTYAALRNS--LTNDAYSRFLGLFNKYKYFSGAMETAAYREAAA 3215
Query 3232 CHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLN 3291
CHLAKAL +S +GSD+LYQPP SITS VLQSG KM+ PSG VE CMVQVTCG+ TLN
Sbjct 3216 CHLAKALQTYSETGSDLLYQPPNCSITSGVLQSGLVKMSHPSGDVEACMVQVTCGSMTLN 3275
Query 3292 GLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQ---AGNVQLRVIGHSMQNC 3348
GLWLD+ V+CPRHV+C ++ + +PNY+ LLI +NH+F VQ LRV+GH+MQ
Sbjct 3276 GLWLDNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVVGHAMQGT 3335
Query 3349 VLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSC 3408
+LKL VD ANP TP Y F ++PG FSVLACYNG P+G + MRPN+TIKGSFL GSC
Sbjct 3336 LLKLTVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCGSC 3395
Query 3409 GSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVL 3468
GSVG+ + ++FCYMH MEL G H G+ +G YG F+D+Q Q TD +VNV+
Sbjct 3396 GSVGYTKEGSVINFCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVNVV 3455
Query 3469 AWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY-EPLTQDHVDILGPLSAQTGIAVLDM 3527
AWLYAA++NG WF+ T++ FN A+ + E + VD+L + +TG+A+ +
Sbjct 3456 AWLYAAILNGCAWFVKPNRTSVVSFNEWALANQFTEFVGTQSVDML---AVKTGVAIEQL 3512
Query 3528 CASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTI 3587
++++L G G+ ILGS +LEDEFTP DV Q GV QS V++ GT HWL T+
Sbjct 3513 LYAIQQLY-TGFQGKQILGSTMLEDEFTPEDVNMQIMGVVMQSGVRKVTYGTAHWLFATL 3571
Query 3588 LTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATV 3647
+++ ++++Q+T+++L+ +L+E + AF M+ VKHKH FL LFLLP +
Sbjct 3572 VSTYVIILQATKFTLWNYLFETIPTQLFPLLFVTMAFVMLLVKHKHTFLTLFLLPVAICL 3631
Query 3648 AYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDD 3703
Y N+VY P +S ++ + WL + + D +Y S ++L+++ R
Sbjct 3632 TYANIVYEPTTPISSALIAVANWLAPTNAYMRTTH-TDIGVYISMSLVLVIVVKRLYNPS 3690
Query 3704 GARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCV 3763
+ L + + +Y G A I+ + ++TS+Y+ V + LA+ +
Sbjct 3691 LSNFALALCSGVMWLYTYSIGEA-SSPIAYLVFVTTLTSDYTITVFVTVNLAKVCTYAIF 3749
Query 3764 EYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYM 3823
Y P + ++ I+L+Y LG+ CTCYFG+F LLN R +GVYD+ VSTQEFR+M
Sbjct 3750 AYSPQLTLVFPEVKMILLLYTCLGFMCTCYFGVFSLLNLKLRAPMGVYDFKVSTQEFRFM 3809
Query 3824 NSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVES 3883
+ L P+NS +A LN KL+G+GG PCIKVA +QSK++D+KCTSVVLLSVLQQL +E+
Sbjct 3810 TANNLTAPRNSWEAMALNFKLIGIGGTPCIKVAAMQSKLTDLKCTSVVLLSVLQQLHLEA 3869
Query 3884 SSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQA 3943
+S+ WA CV+ HNDIL A D +EAFEK VSL + L++ G VD++ L ++ D + LQA
Sbjct 3870 NSRAWAFCVKCHNDILAATDPSEAFEKFVSLFATLMTFSGNVDLDALASDIFDTPSVLQA 3929
Query 3944 IASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKLE 4002
SEFS L ++A AQ+AY++A+ +GD S VLK L+K++N+AK+ +++D A+ RKLE
Sbjct 3930 TLSEFSHLATFAELEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKNAYEKDKAVARKLE 3989
Query 4003 KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII 4062
+MADQAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN II+NAR+GC+PL++I
Sbjct 3990 RMADQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIPLSVI 4049
Query 4063 PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL 4122
PL + KL VVIPD+ + + YA ALW+I + + D++IV+ S++ +D++ NL
Sbjct 4050 PLCASNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDV-VDSNENL 4108
Query 4123 AWPLIVTALRAN-SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFV 4181
WPL++ RA+ SAVKLQNNE+ P L+ M +AG QT C + ++LAYY +G + +
Sbjct 4109 TWPLVLECTRASTSAVKLQNNEIKPSGLKTMVVSAGQEQTNC-NTSSLAYYEPVQGRKML 4167
Query 4182 LALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGM 4241
+ALLSD LKWAR DG ++ EL+PPC+F+ PKGP+++YLYF+K LNNL+RG
Sbjct 4168 MALLSDNAYLKWARVEGKDGFVSV--ELQPPCKFLIAGPKGPEIRYLYFVKNLNNLHRGQ 4225
Query 4242 VLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTH 4301
VLG +AATVRLQAG+ TE +NS+VLS F VD KAY D++ +GG P+TNCVKML
Sbjct 4226 VLGHIAATVRLQAGSNTEFASNSSVLSLVNFTVDPQKAYLDFVNAGGAPLTNCVKMLTPK 4285
Query 4302 TGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPV 4361
TGTG AI+V PE+ DQE++GGAS CLYCR HI+HP+ G C KGK+VQIP C DPV
Sbjct 4286 TGTGIAISVKPESTADQETYGGASVCLYCRAHIEHPDVSGVCKYKGKFVQIPAQCVRDPV 4345
Query 4362 GFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNR 4402
GF L NT C VC W GYGC+CD LR+ L + +FLN
Sbjct 4346 GFCLSNTPCNVCQYWIGYGCNCDSLRQAALPQSKDSNFLNE 4386
Score = 275 bits (703), Expect = 1e-71, Method: Compositional matrix adjust.
Identities = 298/1189 (25%), Positives = 516/1189 (43%), Gaps = 143/1189 (12%)
Query 101 GETLGVLVPHVGEIPVAYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQEN 160
G+ +G+ P+ E+ + +LLRK G GG+ Y ++ + + +DF+ +
Sbjct 123 GKPIGMFFPYDIELVTGKQNILLRKYGR---GGYHYTP--FHYERDNTSCPEWMDDFEAD 177
Query 161 WNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCT-LSEQL 219
K++ + L+++L GG T VD CG DG P+ L+A+ G + +
Sbjct 178 PKGKYA----QNLLKKLIGGDVTP-VDQYMCGVDGKPISAYAFLMAKDGITKLADVEADV 232
Query 220 DFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNS 279
G + + + + W+ ER + Y Q+ F I + D P++ F L
Sbjct 233 AARADDEGFITLKNNLYRLVWHVERKDVPYPKQSIFTINSVVQKDGVENTPPHY-FTLGC 291
Query 280 IIKTIQPR----------VEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGET 329
I T+ PR +++K L F G+ S + S ++C CG
Sbjct 292 KILTLTPRNKWSGVSDLSLKQKLLYTFYGK-------ESLENPTYIYHSAFIECGSCGND 344
Query 330 SWQTGDFVKATCEFCGTENLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGP--EHSLAE 386
SW TG+ ++ CG + + G + NA++ CP +HS+A+
Sbjct 345 SWLTGNAIQGFACGCGASYTANDVEVQSSGMIKPNALLCATCPFAKGDSCSSNCKHSVAQ 404
Query 387 ---YHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGS 443
Y +E I T+ FGG ++Y GC Y+VPRA + + + G
Sbjct 405 LVSYLSER-CNVIADSKSFTLIFGGVAYAYFGCEEGTMYFVPRAKSVVSRIGDSIF-TGC 462
Query 444 EGLNDNLLEI----LQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAF 499
G + + +I L++ + ++N VG+F +N+ + IL+ + + + +KG+
Sbjct 463 TGSWNKVTQIANMFLEQTQHSLNFVGEFVVNDVVLAILSGTTTNVDKIRQLLKGVTLDKL 522
Query 500 KQIVESCGNFKVTKGKAKKGAWNIG----EQKSILSPLYAFAS--EAARVVRSIFSRTLE 553
+ + + VT G A N+G + +I +P E+ + V +I +
Sbjct 523 RDYLADY-DVAVTAGPFMDNAINVGGTGLQYAAITAPYVVLTGLGESFKKVATIPYKVCN 581
Query 554 TAQNSV-----RVLQKAAITILD-GISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQ 607
+ ++++ VL + +D G+S +S L D + DL+ V Y ++Q
Sbjct 582 SVKDTLTYYAHSVLYRVFPYDMDSGVSSFSELLFDCV----DLS----VASTYFLVRLLQ 633
Query 608 -LTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
T +++ I + + +LD E + FL D + + A V
Sbjct 634 DKTGDFMSTIITSCQTAVSKLLDTCFEATEATFNFLLDLAGLFRIFLRNAYVYTSQGFVV 693
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKA-LNLGETFVTHSKGLYRKCVKSR- 724
++ V+ L+NK + L + G+ + A + G + G Y CV ++
Sbjct 694 VNGKVSTLVKQVLDLLNKGMQLLHTKVSWAGSNISAVIYSGRESLIFPSGTYY-CVTTKA 752
Query 725 ----EETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDL-----QPLEQPTSEAVE 775
++ +++P + K+ + G PT+ T V + ++ LEQ + +
Sbjct 753 KSVQQDLDVILPGEFSKKQL---GLLQPTDNSTTVSVTVSSNMVETVVGQLEQTNMHSPD 809
Query 776 APLVGTPVCINGLMLLEIKDTEKYCALAP---NMMVTNNTFTLKGGAPTK-VTFGDDTVI 831
+VG V I+ + + K+ + + A P N F LKGGAP K V FG D V
Sbjct 810 V-IVGDYVIISEKLFVRSKEEDGF-AFYPACTNGHAVPTLFRLKGGAPVKKVAFGGDQVH 867
Query 832 EVQGYKSVNITFELDERIDKVL-NEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL 890
EV +SV + + + +D +L + + V+ + EFA VV + V L + +
Sbjct 868 EVAAVRSVTVEYNIHAVLDTLLASSSLRTFVVDKSLSIEEFADVVKEQVSDLLVKLLRGM 927
Query 891 TPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEE---EEFEPSTQY 947
DLD++ A Y F+ G+ +S M S +P + DEE + E EE E
Sbjct 928 PIPDFDLDDFIDAPCYCFNAEGDASWSSTMIFSLHPVECDEECSEVEASDLEEGESECIS 987
Query 948 EYGTE----------DDY-----QGKPL-EFGATSAALQPEEEQEEDWLDDDSQQTVGQQ 991
E TE D++ + PL E + ++Q E + E ++D +Q +
Sbjct 988 ETSTEQVDVSHEISDDEWAAAVDEAFPLDEAEDVTESVQEEAQPVEVPVEDIAQVVIADT 1047
Query 992 DGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIE--------------------------- 1024
+T + VEV PQ+ ++L QTI+
Sbjct 1048 L----QETPVVSDTVEVPPQV-VKLPSEPQTIQPEVKEVAPVYEADTEQTQSVTVKPKRL 1102
Query 1025 -----VNSFSGYLK--LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
V+ S + +T+ V I D ++ AK +V+VNAAN +LKHGGG+AGA+N
Sbjct 1103 RKKRNVDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHGGGIAGAINA 1162
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
A+ A+Q ESD+YI GPL+VG S +L GH+LAK+ LHVVGP+ +D+ LL Y+
Sbjct 1163 ASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSLLSKCYKA 1222
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKL 1186
N + +++ PL+SAGIFG P S + +T V + V +++Y L
Sbjct 1223 MNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSL 1271
>sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus
HKU5 OX=694008 GN=1a PE=3 SV=1
Length=4481
Score = 2172 bits (5629), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1223/3125 (39%), Positives = 1809/3125 (58%), Gaps = 140/3125 (4%)
Query 1391 VCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPL 1450
+C + A ++ + + + VD G ++Y Y+SK + +I N + + MP+
Sbjct 1379 ICTDQSANAKLLKGRGVDLTKKTQTVD-GVKYYLYSSKDPLTDIITAANAC-KGICAMPI 1436
Query 1451 GYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGS 1510
GYVTHGL+L +A + ++ + VP ++S D V N + + +TPE+ FI T+ G
Sbjct 1437 GYVTHGLDLAQAGQQVKKITVPYVCLLASKDQVPILNSDV--AVQTPEQSFINTVIANGG 1494
Query 1511 YKDWSY-SGQSTQLGIEF---LKRGDKSVYYTSNPTTFHLDGEV-ITFDNL---KTLLSL 1562
Y W +G+ G+ + L D+++ Y N + + G++ + FD+L +T L+
Sbjct 1495 YHCWHLVTGELIVKGVSYRKLLNWSDQTICYADN-KFYVVKGQIALPFDSLEKCRTYLTS 1553
Query 1563 R--EVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
R + + + V T+D +N T V++ + TY Q G + G+D++ P G+ Y+
Sbjct 1554 RAAQQKNVDVLVTIDGVNFRTVVLNNTTTYRVQLGSVFYKGSDISDTIPTEKMSGEAVYL 1613
Query 1621 LPN-DDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATA 1679
N + + E Y T D +FL RY S L KKWKY +G+ S+K NNCY+
Sbjct 1614 ADNLSEAEKAVLSEVYGTADTAFLHRYYSLLALVKKWKYTVHDGVKSLKLNSNNCYVNVT 1673
Query 1680 LLTLQQI-ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQH 1738
+L L + E+KF PALQ AY + + G++ F ALI+AY + T GE D + +
Sbjct 1674 MLMLDMLKEIKFIVPALQAAYLKHKGGDSTEFIALIMAYGDCTYGEPDDASRLLHTILSK 1733
Query 1739 ANLDS-CKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYL 1797
A L + K V C CG Q TT G++A +Y+G S ++ + C CG + L
Sbjct 1734 AELTTQAKMVWRQWCNVCGVQDTTTTGLKACIYVGMNSLDELHATHEECCQCGDVRKRQL 1793
Query 1798 VQQESPFVMMSAPPAQYELKHGTFTCASEYTG-------NYQCGHYKHITSKETL-YCID 1849
V+ +P++++S + + + +YT GHY H+ K+ L Y D
Sbjct 1794 VEHNAPWLLLSGLNEAKVMTPTSQSAGPDYTAFNVFQGVETSVGHYLHVRVKDNLLYKYD 1853
Query 1850 GALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTE 1909
L+K+S+ K +TDV+Y + Y+ V Y LDG ++DP L +Y KD YFT+
Sbjct 1854 SGSLSKTSDMKCKMTDVYYPKQRYSADCNVVVYSLDGNTWADVDPDLSAFYMKDGKYFTK 1913
Query 1910 QPI------DLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGY--KKPASRELKVTFFP 1961
+P+ ++ Y N+ + + N L G+ KP S++L +FFP
Sbjct 1914 KPVIEYSPATILSGSVYTNSCLVGHDGTIGSDAISSSFNNLLGFDNSKPVSKKLTYSFFP 1973
Query 1962 DLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVET 2021
D GDV+ +Y Y P +K GA L KPI+W N+ + A K N +R ++ PV
Sbjct 1974 DFEGDVILTEYSTYDPIYKNGAMLHGKPILWVNNSKFDSALNKFNRATLRQVYDIAPVTL 2033
Query 2022 SNSFDVLKSEDAQGMDNLAC-EDLKPVSE-EVVENPTIQKDVLECNVKTTEVVGD---II 2076
N + VL+ Q ++ A ED KP S +V E+ + +++C V D +
Sbjct 2034 ENKYTVLQDNQIQQVEVEAPKEDAKPQSPVQVAEDIDNKLPIIKCKGLKKPFVKDGYSFV 2093
Query 2077 LKPANNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPW 2135
P + + + +G DL A YVD N L + K N S + + T+ L+ + +
Sbjct 2094 NDP--QGVNVIDTLGIDDLRALYVDRNLRLIVLKENNWSALFNIHTVEKGDLSVIAASGS 2151
Query 2136 DT----IANYAKPFLNKVVSTTTNIVT---RCLNRVCTNYMP------YFFTLLLQLC-- 2180
T I A + S T N+ T + L R+ N + F LL L
Sbjct 2152 ITRRVKILLGASSLFAQFASVTVNVTTAMGKALGRMTRNVITNTGIIGQGFALLKMLLIL 2211
Query 2181 --TFTRSTN-SRIKASMPTTIAKNTVKS-VGKFCLEASFNYLKSPNFSKLINIIIWFLLL 2236
TF +S N S +K + V + V K C A+++ L F ++ LL
Sbjct 2212 PFTFWKSKNQSTVKVEVGALRTAGIVTTNVVKQCASAAYDVLVV-KFKRIDWKSTLRLLF 2270
Query 2237 SVC------------------LGSLIYSTAALGVLM------SNLGMPSYCTGYREGYLN 2272
+C L S + A G+L S LG+ S C G E Y N
Sbjct 2271 LICTTGLLLSSLYYLFLFHQVLTSDVMLDGAEGMLATYRELRSYLGIHSLCDGMVEAYRN 2330
Query 2273 STNVTIATYCTG-SIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAY 2331
+ + +C+ S C+ CL G DSL Y + + IQ ++S+ ++ V E+ LAY
Sbjct 2331 -VSYDVNDFCSNRSALCNWCLIGQDSLTRYSAFQMIQTHVTSYVINIDWVWFVMEFALAY 2389
Query 2332 ILFTRFFYVLGLAAIMQLFFSYFA--VHFISNSWLMWLIINLVQMAPISAMVRMYIFFAS 2389
+L+T F VL L Q FFSY V++ S ++L+ V P+ +VR+Y F A
Sbjct 2390 VLYTSTFNVLLLVVSSQYFFSYTGAFVNWRSYNYLVSGYFFCVTHIPLLGLVRIYNFLAC 2449
Query 2390 FYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHN 2449
+++ + Y HV++GC + C++CYKRNR TRVE +T+V G +R+FY+ ANGG FC HN
Sbjct 2450 LWFLRRFYNHVINGCKDTACLLCYKRNRLTRVEASTVVCGSKRTFYIVANGGTSFCCRHN 2509
Query 2450 WNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAG 2509
WNCV+CDT G+TFI +EVA DL+ +R + PTD+S Y V+SVTVK+ + L++ + G
Sbjct 2510 WNCVDCDTAGIGNTFICEEVANDLTTSLRRLVKPTDKSHYYVESVTVKDSVVQLHYSREG 2569
Query 2510 QKTYERHSLSHFVNLDNLRAN---NTKGSLP-INVIVFDGKSKCEESSAKSASVYYSQLM 2565
YER+ L +F NLD L+ T +P N +++D + +E+ A+SA VYYSQ++
Sbjct 2570 ASCYERYPLCYFTNLDKLKFKEVCKTPTGIPEHNFLIYDSSDRGQENLARSACVYYSQVL 2629
Query 2566 CQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVS 2625
+P+LL+D +V+ VGDS E+A KM D+YVN+F S F V +KL LVATA + +
Sbjct 2630 SKPMLLVDSNMVTTVGDSREIASKMLDSYVNSFISLFGVNRDKLDKLVATARDCVKRGDD 2689
Query 2626 LDNVLSTFISAAR-QGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMT 2684
V+ TF AAR V+SDVET +V+ L+ +++ D+++T + NNY+ +Y K +++
Sbjct 2690 FQTVIKTFTDAARGPAGVESDVETSSIVDALQYAYKHDLQLTTEGFNNYVPSYIKPDSVA 2749
Query 2685 PRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTC 2744
DLG ID +A +N ++ N A IWN D+M LS+ L++QIR A +K N+PF+LT
Sbjct 2750 TADLGCLIDLNAASVNQTSIRNANGACIWNSSDYMKLSDSLKRQIRIACRKCNIPFRLTT 2809
Query 2745 ATTRQVVNVVTTKIA---LKGGKIVNNWL--------KQLIKVTLVFLFVAAIFYLITPV 2793
+ R N+++ K + L GG WL K VTLV +A + YL P
Sbjct 2810 SRLRSADNILSVKFSATKLSGG--APKWLLKLRDFTWKSYCVVTLVVFAMAVLSYLCLPA 2867
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQR-GGSYTNDKACP 2852
MS+ + I+ YK ++ G+ RDI +DTCFANK+ F WF++ GG + ND +CP
Sbjct 2868 FNMSQVSFHEDRILTYKVVENGIIRDITPSDTCFANKYQSFSKWFNEHYGGLFNNDISCP 2927
Query 2853 LIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSA 2912
+ AVI G VP LP + L F+ RVF++ N+CYTP+ I Y F+ S
Sbjct 2928 VTVAVIAGVAGARVPNLPANVAWVGRQIVL-FVSRVFASSNNVCYTPTAEIPYERFSDSG 2986
Query 2913 CVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSI-IQFPNTYLEG 2971
CVLA+ECT+F+DA GK PYCYD VL G+ AY+ ++P RY + D + I+FP E
Sbjct 2987 CVLASECTLFRDAEGKINPYCYDPTVLPGASAYDQMKPHVRYDMYDSDMYIKFPEVVFES 3046
Query 2972 SVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMF 3031
++R+ T + YCR G+CE + GVC++T+G W + ND+Y + PGV+CG + +++ +
Sbjct 3047 TLRITKTLATRYCRFGSCEDANEGVCITTNGSWAIYNDHYANKPGVYCGDNYFDIVRRLG 3106
Query 3032 TPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTV 3091
L QP+ +S S+ G ++ I +T YY + +RA +Y+ L++
Sbjct 3107 LSLFQPVTYFQLSTSLALGVMLCIFLTIAFYYVNKVKRALADYTQCAVVAVAAALLNSLC 3166
Query 3092 LCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTK 3151
LC L Y+ +Y Y TFYLT + +F+ H+ W VMF +VP W+ AYI+ + +
Sbjct 3167 LCFVVSNPLLVLPYTALYYYATFYLTGEPAFVMHVSWFVMFGTVVPIWMVFAYIVGVCLR 3226
Query 3152 HFYWFFSNYLKRRV-VF-NGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQ--YNRY 3207
H W + + K+ V VF +G +F++AA F++NK+ Y+ LR+ + TQ YNRY
Sbjct 3227 HLLWVMAYFSKKHVEVFTDGKLNCSFQDAAANIFVINKDTYVALRNSI----TQDSYNRY 3282
Query 3208 LALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFR 3267
L+++NKYKY+SGAMDT SYREA+ HL KAL +S +GSDVL+QPP S+TS+VLQSG
Sbjct 3283 LSMFNKYKYYSGAMDTASYREASAAHLCKALQVYSETGSDVLFQPPNCSVTSSVLQSGLV 3342
Query 3268 KMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNH 3327
KMA PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+ LL+ K+N
Sbjct 3343 KMAAPSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDALLVSKTNL 3402
Query 3328 NFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGS 3384
+F+VQ LRV+GH+M +LKL V++ANP+TP Y F ++PG +FSVLACYNG
Sbjct 3403 SFIVQKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFSVLACYNGR 3462
Query 3385 PSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNF 3444
P+GV+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H G +G
Sbjct 3463 PTGVFMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHTGCAFDGVM 3522
Query 3445 YGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY-E 3503
YG F DRQ Q +D T+N++AWLYAA++NG WF+ T + FN AM + E
Sbjct 3523 YGAFEDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEWAMSNQFTE 3582
Query 3504 PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQC 3563
+ VD+L + +TG++V + ++ + L G G+TILG+++LEDEFTP DV Q
Sbjct 3583 FIGTQSVDML---AHKTGVSVEQLLYAI-QTLHKGFQGKTILGNSMLEDEFTPDDVNMQV 3638
Query 3564 SGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSA 3623
GV QS VKR G HWL T+L + + +Q T+++++ +L+E L ++ + A
Sbjct 3639 MGVVMQSGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLTPLVLCVMA 3698
Query 3624 FAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKL 3679
M+ VKHKH FL LFLLP+ + Y N+VY P +S ++ + WL+ +
Sbjct 3699 CVMLTVKHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPASVYMRTTH- 3757
Query 3680 KDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIIS 3739
D +Y S L ++ R + + L + + Y G+ ++ + +
Sbjct 3758 TDLGVYLSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPLTYLMFLTT 3816
Query 3740 VTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCL 3799
+TS+Y+ V + +A+ + Y P ++ ++L+Y +GYFCT YFG+F L
Sbjct 3817 LTSDYTVTVFLAVNVAKFFARVVFLYAPHAGFIFPEVKLVLLMYLAVGYFCTVYFGVFSL 3876
Query 3800 LNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQ 3859
LN R+ LGVYDY VSTQEFRY+ GL P+NS +A +LN+KL+G+GG PCIK+A+VQ
Sbjct 3877 LNLKLRVPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTPCIKIASVQ 3936
Query 3860 SKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLL 3919
SK++D+KCTSVVLLSVLQQL +E++SK WA CV+LHNDIL A D TEAF+ V L + L+
Sbjct 3937 SKLTDLKCTSVVLLSVLQQLHLEANSKAWAHCVKLHNDILAATDPTEAFDNFVCLFATLM 3996
Query 3920 SMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLK 3978
S VD+ L ++LD+ + LQA SEFS L SYA AQ +Y++A+ +GD S VLK
Sbjct 3997 SFSANVDLEALASDLLDHPSVLQATLSEFSHLASYAELEAAQSSYQKALNSGDASPQVLK 4056
Query 3979 KLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLR 4038
L+K++N+AK+ +++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++
Sbjct 4057 ALQKAVNIAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIK 4116
Query 4039 KLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEI 4098
KLDND LN +I+NAR+GCVPL+++PL + KL VVIPD + + +YA ALW+I
Sbjct 4117 KLDNDVLNGVISNARNGCVPLSVVPLCASNKLRVVIPDITIWNKVVTWPSLSYAGALWDI 4176
Query 4099 QQVVDADSKIVQLSEISMDNSPNLAWPLIVTALR-ANSAVKLQNNELSPVALRQMSCAAG 4157
+ + D ++V+ S+++ N +L WPL++ R A+SAV LQNNE+ P L+ M +AG
Sbjct 4177 SLINNVDGEVVKSSDVTETNE-SLTWPLVLECTRAASSAVTLQNNEIRPSGLKTMVVSAG 4235
Query 4158 TTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVT 4217
C + ++LAYY +G + ++ +LS+ LKWA+ DG I EL+PPC+F+
Sbjct 4236 IDHANC-NTSSLAYYEPVEGRKMLMGILSENAHLKWAKVEGRDGFVNI--ELQPPCKFLI 4292
Query 4218 DTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAA 4277
PKGP+V+YLYF+K LNNL+RG +LG +AATVRLQAG+ TE NS+VLS F+VD
Sbjct 4293 AGPKGPEVRYLYFVKNLNNLHRGQLLGHIAATVRLQAGSNTEFAINSSVLSAVTFSVDPG 4352
Query 4278 KAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHP 4337
KAY D++ +GG P+TNCVKML TGTG A++V PEAN DQ+++GGAS CLYCR HI+HP
Sbjct 4353 KAYLDFVNAGGAPLTNCVKMLTPKTGTGIAVSVKPEANADQDTYGGASVCLYCRAHIEHP 4412
Query 4338 NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQ 4397
+ G C KGK+VQ+P DPVGF L+NT C VC W G+GC+CD LR + +
Sbjct 4413 DVTGVCKFKGKFVQVPLHI-RDPVGFCLQNTPCNVCQFWIGHGCNCDALRGTTIPQSKDS 4471
Query 4398 SFLNR 4402
+FLN
Sbjct 4472 NFLNE 4476
Score = 178 bits (451), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 250/1066 (23%), Positives = 445/1066 (42%), Gaps = 91/1066 (9%)
Query 13 HVQLSLPVLQVRDVLVR---GFGDSVEEVLSEARQHLKDGTCGLV--EVEKGVLPQLEQP 67
HV L + D++++ F D E + L G+ L + KG + L P
Sbjct 28 HVSLKASLCDAGDLVLKISPWFMDG-ESAYKHVSEQLSKGSKLLFVPQTLKGFIRHLPGP 86
Query 68 YVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETL-----GVLVPHVGEIPVAYRKVL 122
V++ MV +A G G TL G+ P ++ + L
Sbjct 87 RVYLVERLTGGTYSDPFMVNQLAYQNAAGEGVIGTTLQGKRVGMFFPFDADLVTGEFQFL 146
Query 123 LRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAY 182
LRK KG GG+ + D + PY D + ++ L+++L GG +
Sbjct 147 LRK---KGFGGNRFR------DAPWDYNWTPYSDLMDALEADPCGKYSQSLLKKLVGGDF 197
Query 183 TRYVDNNFCGPDGYPLECIKDLLARAG--KASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
T +D CG +G P+ L+A G K + +E D+ R + + + I W
Sbjct 198 TP-IDQYMCGKNGKPIAEFAALMASEGITKLADVEAEVKSRTDSDRYI-VFKNKLYRIVW 255
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+R + +Y Q+ F + + DT + P F + S I+ I P + +
Sbjct 256 NVQRKDVAYSKQSAFTMNSIVQLDTME-DVPRHSFTIGSEIQVIAPSTAVQANGHLNLKQ 314
Query 301 RSVYPV---ASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKE-GATT 356
R +Y + +E N + S + C CG+ SW TG+ V+ CG + +
Sbjct 315 RLLYAFYGKQAVSEPNYIYHSAYVDCTSCGKGSWLTGNAVQGFACDCGAHYCANDVDLQS 374
Query 357 CGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRT--IAFGGCVFSYV 414
G + +NAV+ CP + E +H+L + + K + G+T + +GG +++Y+
Sbjct 375 SGLVRKNAVLLTTCPCNKDGEC--KHTLPQLVSMMTDKCDVEVVGKTFILTYGGVIYAYM 432
Query 415 GCHNKCAYWVPRASA---NIG-CNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLN 470
GC +++PRA + IG TG G S+ L L++ + IN V +F L
Sbjct 433 GCSGGTMHFIPRAKSCVSKIGDAIFTGCTGTWSKVCETANL-FLERAQHAINFVNEFVLT 491
Query 471 EEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSIL 530
E + +L+ ++S + + ++ + + G + VT G +G N+G
Sbjct 492 ETVVALLSGTTSSIEELRDLCRNATFEKVRDYLTPRG-WIVTMGSYIEGVINVGAAGVCN 550
Query 531 SPLYA-----------FASEAARVVR--SIFSRTLETAQNSV--RVLQKAAITILDGISQ 575
+ L A F AA + S TL+ +S+ RV I ++
Sbjct 551 AALNAPFIVLSGLGESFKKVAATPWKLCSSLRETLDHYADSITYRVF---PYDIPCDVTD 607
Query 576 YSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKF 635
Y+ L+D + T A V Y+ V QLT+ +F + + + +
Sbjct 608 YTALLLDCAVLTGASA---YFVARYVDEKVEQLTNL----VFSSCQSAVAAFVQACMSTY 660
Query 636 KEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIII 695
K +F+ D + ++K +S V + ++ F +++K + L ++
Sbjct 661 KATAKFISDMFTLIKVVSERLYVYTSVGFVVVGDYSSQLLKQFMHILSKAMQLLHTTVSW 720
Query 696 GGAKLKAL--NLGETFVTHSKGLYRKCVKSR---EETGLLMPLK-APKEIIFLE----GE 745
G+KL ++ N ++ V S Y + R ++ L++P + K+I LE
Sbjct 721 AGSKLPSVVYNGRDSLVFPSGTYYCVSTQGRSLQDQFDLVIPGDLSKKQIGILEPTPNST 780
Query 746 TLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCI-NGLMLLEIKDTEK-YCALA 803
T+ ++ T V + G L+P ++ + E V VG V I N + + ++D+E + L
Sbjct 781 TVDKKINTNVVEVVVGQLEPTKEHSPELV----VGDYVIISNKIFVRSVEDSETVFYPLC 836
Query 804 PNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSVNITFELDERIDKVL-NEKCSAYT 861
+ + F LKGGAP K V FG + E+ +SV++ +++ +D +L + + +T
Sbjct 837 TDGKIVPTLFRLKGGAPPKGVKFGGEQTKEITAVRSVSVDYDVHPVLDALLAGSELATFT 896
Query 862 VELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMY 921
VE V +F VV D VI+ L + G DL++++ Y+++ G+ +S M
Sbjct 897 VEKDLPVKDFVDVVKDEVIELLSKLLRGYNVDGFDLEDFADTPCYVYNAEGDLAWSSTMT 956
Query 922 CSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLD 981
S P +E EEE D + E E ++ ED+ + A A+ P E+ + D L
Sbjct 957 FSVNPVEEVEEECDDDYVEDEYLSEEMLVEEDEN-----SWAAAVEAVIPMEDVQLDTLV 1011
Query 982 DDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNS 1027
+ + D +E T VEV +E + V EV S
Sbjct 1012 AEIDVSEPADDVAEQASTEE----VEVPSACVLEASQVANAAEVES 1053
Score = 138 bits (348), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 66/158 (42%), Positives = 102/158 (65%), Gaps = 0/158 (0%)
Query 1031 YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDY 1090
++ L ++V + D + A+ + ++VNAAN +LKHGGG+A A+++A+ +Q ESDDY
Sbjct 1192 HIVLNNDVTLVFGDAIAVARATEDCILVNAANTHLKHGGGIAAAIDRASGGLVQAESDDY 1251
Query 1091 IATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ GPL VG S +L GH LA LHVVGP+ +DIQLLK Y+ FN++ ++++PL+S
Sbjct 1252 VNFYGPLNVGDSTLLKGHGLATGILHVVGPDARANQDIQLLKRCYKAFNKYPLVVSPLIS 1311
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS 1188
AGIF +P SL + V T Y+ V + +Y+ L +
Sbjct 1312 AGIFCVEPRVSLEYLLSVVHTKTYVVVNSEKVYNDLAA 1349
>sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=1a PE=3 SV=1
Length=4383
Score = 1872 bits (4849), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1073/2886 (37%), Positives = 1630/2886 (56%), Gaps = 125/2886 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + +G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGENFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + I D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTI--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVD 2101
D K E+ I L K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAK-------ESKEINIIKLSGVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLT 2080
Query 2102 NSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNIV 2157
++ N+LS + + T+ G+ V S+P D + KP N VV N +
Sbjct 2081 GCRYVVRTANDLSMAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNKI 2138
Query 2158 TRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNY 2217
+ C N ++ + F LL + K T +A + + +F
Sbjct 2139 SACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFLT 2189
Query 2218 LKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTN 2275
K ++ II I+ L + ++I+S L +G G ++ ST
Sbjct 2190 FKWSVVARGACIIATIFLLWFNFIYANVIFSDFYL----PKIGFLPTFVGKIAQWIKSTF 2245
Query 2276 --VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAF 2321
VTI YC GSI C CL+G D LD Y +++ +Q ++ D AF
Sbjct 2246 SLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRAF 2300
Query 2322 -------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLV 2372
+V E ++Y L+T +FY L +Q+ ++ F+ ++ W + L+++L
Sbjct 2301 VDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLA 2360
Query 2373 QMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRR 2432
M P +R YI ASF ++ + HV GC+ C+ CYKRNR+ RV+C+TIV G+ R
Sbjct 2361 NMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIR 2420
Query 2433 SFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVD 2492
+ V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2421 YYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVT 2480
Query 2493 SVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES 2552
V + L++++ GQ+TY+ + S FV+ NL + KG ++V+V + + +++
Sbjct 2481 DVKQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVENDA--DKA 2538
Query 2553 SAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTL 2612
+ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L L
Sbjct 2539 NFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNAL 2598
Query 2613 VATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCN 2671
+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SCN
Sbjct 2599 IATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCN 2658
Query 2672 NYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRS 2731
N + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2659 NLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKK 2718
Query 2732 AAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLIT 2791
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2719 ACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFLLSLV-CFIG--LWCLM 2775
Query 2792 PVHVMSKHTDFSSEI-IGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTND 2848
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2776 PTYTVHK-SDFQLPVYTSYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSNS 2834
Query 2849 KACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDF 2908
ACP++ AV+ +++G V +P +LR LHF+ SA G CYTP I Y++F
Sbjct 2835 MACPIVVAVVDQDLGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSNF 2893
Query 2909 ATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPNT 2967
S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2894 YASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGFIRFPEV 2953
Query 2968 YLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLL 3027
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L+
Sbjct 2954 LREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDLI 3013
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
+F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ +V N +++ +
Sbjct 3014 YQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWCV 3073
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIIC 3147
+F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3074 NFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYISV 3133
Query 3148 ISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRY 3207
+ + H +W F+ RR+ + S TFEE AL TF++ K+ Y KL++ L +NRY
Sbjct 3134 VVSNHAFWVFA--YCRRLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNRY 3189
Query 3208 LALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSGF 3266
L+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3190 LSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSGI 3249
Query 3267 RKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSN 3326
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R ++
Sbjct 3250 VKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVTS 3309
Query 3327 HNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPS 3386
+F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3310 SDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKPQ 3369
Query 3387 GVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYG 3446
G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+FYG
Sbjct 3370 GAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGDFYG 3429
Query 3447 PFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLT 3506
P+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3430 PYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQVK 3489
Query 3507 QDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGV 3566
D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q +G+
Sbjct 3490 SDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAGI 3546
Query 3567 TFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAM 3626
QS R +KG W++ + ++ +W++F ++ N L + + + AM
Sbjct 3547 KLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAM 3605
Query 3627 MFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMY 3685
+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3606 LLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIY 3664
Query 3686 ASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNY 3744
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y
Sbjct 3665 GMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTY 3722
Query 3745 SGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYF 3804
+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N F
Sbjct 3723 TWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLF 3781
Query 3805 RLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSD 3864
R+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++D
Sbjct 3782 RMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLTD 3841
Query 3865 VKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGA 3924
VKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL + A
Sbjct 3842 VKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPAA 3901
Query 3925 VD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVL 3977
VD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + + L
Sbjct 3902 VDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQL 3961
Query 3978 KKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTML 4037
K+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+
Sbjct 3962 KQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMV 4021
Query 4038 RKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWE 4097
RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W+
Sbjct 4022 RKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQ 4081
Query 4098 IQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCA 4155
IQ + D+D QL+EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4082 IQTIQDSDGTNKQLNEISDDCN----WPLVIIANRHNEVSATVLQNNELMPAKLKTQVVN 4137
Query 4156 AGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRF 4215
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4138 SGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCKF 4194
Query 4216 VTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVD 4275
KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+VD
Sbjct 4195 TVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSVD 4254
Query 4276 AAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHID 4335
K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+YCR ++
Sbjct 4255 PKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIYCRARVE 4314
Query 4336 HPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSAD 4395
HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS D
Sbjct 4315 HPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSKD 4372
Query 4396 AQSFLN 4401
+FLN
Sbjct 4373 T-NFLN 4377
Score = 83.2 bits (204), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 79/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFD 1425
Score = 76.3 bits (186), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 207/933 (22%), Positives = 355/933 (38%), Gaps = 164/933 (18%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E S+ L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSLDSLS-AAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F+++ I ++ S V +
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKN---IPRYASA-----VAQAFRS 709
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK + +S++ F + I + G+K+ + G + HS L +
Sbjct 710 VAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP KA ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A +VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRRVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVVDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDE 931
+ + +LFDE+GE LAS +YC+F P++D+
Sbjct 936 KLEDNSLFLFDEAGEEVLASKLYCAFTAPEDDD 968
>sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=1a PE=3 SV=1
Length=4383
Score = 1871 bits (4847), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1073/2886 (37%), Positives = 1631/2886 (57%), Gaps = 125/2886 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E +P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYNPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + I D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTI--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVD 2101
D K E+ I L K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAK-------ESKEINIIKLSGVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLT 2080
Query 2102 NSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNIV 2157
++ N LS + + T+ G+ V S+P D + KP N VV N +
Sbjct 2081 GCRYVVRTANALSMAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNKI 2138
Query 2158 TRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNY 2217
+ C N ++ + F LL + K T +A + + +F
Sbjct 2139 SACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFLT 2189
Query 2218 LKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTN 2275
K ++ II I+ L + ++I+S L +G G ++ ST
Sbjct 2190 FKWSVVARGACIIATIFLLWFNFIYANVIFSDFYL----PKIGFLPTFVGKIAQWIKSTF 2245
Query 2276 --VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAF 2321
VTI YC GSI C CL+G D LD Y +++ +Q ++ D AF
Sbjct 2246 SLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRAF 2300
Query 2322 -------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLV 2372
+V E ++Y L+T +FY L +Q+ ++ F+ ++ W + L+++L
Sbjct 2301 VDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLA 2360
Query 2373 QMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRR 2432
M P +R YI ASF ++ + HV GC+ C+ CYKRNR+ RV+C+TIV G+ R
Sbjct 2361 NMLPAHVFMRFYIIIASFIKLFILFRHVAYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIR 2420
Query 2433 SFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVD 2492
+ V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2421 YYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVT 2480
Query 2493 SVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES 2552
V + L++++ GQ+TY+ + S FV+ NL + KG ++V+V + + +++
Sbjct 2481 DVKQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVENDA--DKA 2538
Query 2553 SAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTL 2612
+ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L L
Sbjct 2539 NFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNAL 2598
Query 2613 VATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCN 2671
+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SCN
Sbjct 2599 IATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCN 2658
Query 2672 NYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRS 2731
N + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2659 NLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKK 2718
Query 2732 AAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLIT 2791
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2719 ACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFLLSLV-CFIG--LWCLM 2775
Query 2792 PVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTND 2848
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2776 PTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSNS 2834
Query 2849 KACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDF 2908
ACP++ AV+ +++G V +P +LR LHF+ SA G CYTP I Y++F
Sbjct 2835 MACPIVVAVVDQDLGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSNF 2893
Query 2909 ATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPNT 2967
S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2894 YASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGFIRFPEV 2953
Query 2968 YLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLL 3027
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L+
Sbjct 2954 LREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDLI 3013
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
+F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ +V N +++ +
Sbjct 3014 YQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWCV 3073
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIIC 3147
+F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3074 NFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYISV 3133
Query 3148 ISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRY 3207
+ + H +W F+ RR+ + S TFEE AL TF++ K+ Y KL++ L +NRY
Sbjct 3134 VVSNHAFWVFA--YCRRLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNRY 3189
Query 3208 LALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSGF 3266
L+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3190 LSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSGI 3249
Query 3267 RKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSN 3326
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R ++
Sbjct 3250 VKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVTS 3309
Query 3327 HNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPS 3386
+F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3310 SDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKPQ 3369
Query 3387 GVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYG 3446
G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G+FYG
Sbjct 3370 GAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGDFYG 3429
Query 3447 PFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLT 3506
P+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3430 PYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQVK 3489
Query 3507 QDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGV 3566
D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q +G+
Sbjct 3490 SDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAGI 3546
Query 3567 TFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAM 3626
QS R +KG W++ + ++ +W++F ++ N L + + + AM
Sbjct 3547 KLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAM 3605
Query 3627 MFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMY 3685
+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+Y
Sbjct 3606 LLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIY 3664
Query 3686 ASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNY 3744
+++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+ Y
Sbjct 3665 GMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTY 3722
Query 3745 SGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYF 3804
+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N F
Sbjct 3723 TWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLF 3781
Query 3805 RLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSD 3864
R+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++D
Sbjct 3782 RMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLTD 3841
Query 3865 VKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGA 3924
VKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL + A
Sbjct 3842 VKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPAA 3901
Query 3925 VD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVL 3977
VD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + + L
Sbjct 3902 VDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQQL 3961
Query 3978 KKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTML 4037
K+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+
Sbjct 3962 KQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMV 4021
Query 4038 RKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWE 4097
RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W+
Sbjct 4022 RKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQ 4081
Query 4098 IQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCA 4155
IQ + D+D QL+EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4082 IQTIQDSDGTNKQLNEISDDCN----WPLVIIANRHNEVSATVLQNNELMPAKLKTQVVN 4137
Query 4156 AGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRF 4215
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4138 SGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCKF 4194
Query 4216 VTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVD 4275
KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+VD
Sbjct 4195 TVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSVD 4254
Query 4276 AAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHID 4335
K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+YCR ++
Sbjct 4255 PKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIYCRARVE 4314
Query 4336 HPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSAD 4395
HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS D
Sbjct 4315 HPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSKD 4372
Query 4396 AQSFLN 4401
+FLN
Sbjct 4373 T-NFLN 4377
Score = 83.2 bits (204), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 79/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFD 1425
Score = 75.9 bits (185), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 207/933 (22%), Positives = 355/933 (38%), Gaps = 164/933 (18%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E S+ L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSLDSLS-AAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F+++ I ++ S V +
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKN---IPRYASA-----VAQAFRS 709
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK + +S++ F + I + G+K+ + G + HS L +
Sbjct 710 VAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP KA ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A +VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRRVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDE 931
+ + +LFDE+GE LAS +YC+F P++D+
Sbjct 936 KLEDNSLFLFDEAGEEVLASKLYCAFTAPEDDD 968
>sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus
OC43 OX=31631 GN=1a PE=1 SV=1
Length=4383
Score = 1860 bits (4819), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1076/2890 (37%), Positives = 1628/2890 (56%), Gaps = 133/2890 (5%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCFKWQVVVNGKYFTFKQANNNCFVNVSCLMLQSLH 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
L F Q+A+ R+G A F AL+LA G+ D R+ + +F +L
Sbjct 1685 LTFKIVQWQEAWLEFRSGRPARFVALVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q G++AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGLDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFIGD-NVGHYVHVKCEQSYQLYDASNVKKVTDVTGKLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + + D LN G+ E K+T +P GDVV + Y +++G
Sbjct 1920 YTNFKLIGHTV--CDSLNSKLGFDSSKEFVEYKITEWPTATGDVVLANDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D + +
Sbjct 1978 ITFGKPVIWLSHEKASLNSLTY----------FNRPLLVDDNKFDVLKVDDVDDSGDSSE 2027
Query 2042 EDLKPVSE-EVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
K E +++ ++K +V +I+ + K + + D+ ++
Sbjct 2028 SGAKETKEINIIKLSGVKKPF--------KVEDSVIVNDDTSETKYVKSLSIVDVYDMWL 2079
Query 2101 DNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNI 2156
++ N LSR + + T+ G+ V S+P D + KP +N VV N
Sbjct 2080 TGCKYVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPAVN-VVKAVRNK 2137
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
+ C N ++ + F LL + K T IA + + +F
Sbjct 2138 TSACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEIASKLTCKLVALAFKNAFL 2188
Query 2217 YLKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLG-MPSYCTGYREGYLNS 2273
K ++ II I+ L + ++I+S L +G +P++ + N+
Sbjct 2189 TFKWSMVARGACIIATIFLLWFNFIYANVIFSDFYL----PKIGFLPTFVGKIAQWIKNT 2244
Query 2274 TN-VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTA 2320
+ VTI YC GSI C CL+G D LD Y +++ +Q ++ D A
Sbjct 2245 FSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRA 2299
Query 2321 F-------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINL 2371
F +V E ++Y L+T +FY L +Q+ ++ F+ ++ W L++ L
Sbjct 2300 FVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSFRLLVAL 2359
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
M P +R YI ASF ++ + HV GC+ S C+ CYKRNR+ RV+C+TIV G+
Sbjct 2360 ANMLPAHVFMRFYIIIASFIKLFSLFKHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMI 2419
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2420 RYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTV 2479
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEE 2551
V S+ L++D+ GQ+ Y+ + S FV+ NL + K ++V+V + + ++
Sbjct 2480 TDVKQVGCSMRLFYDRDGQRIYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DK 2537
Query 2552 SSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKT 2611
++ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L
Sbjct 2538 ANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNA 2597
Query 2612 LVATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSC 2670
L+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SC
Sbjct 2598 LIATAHSSIKQGTQIYKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESC 2657
Query 2671 NNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIR 2730
NN + TY K +N+ DLG I SA+H+ VAK ++ IW+V F S + +++
Sbjct 2658 NNLVPTYLKSDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQFSSDFQHKLK 2717
Query 2731 SAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLI 2790
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2718 KACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLV-CFIG--LWCL 2774
Query 2791 TPVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTN 2847
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2775 MPTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2848 DKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTD 2907
ACP++ AVI ++ G V +P +LR LHF+ SA G CYTP I Y++
Sbjct 2834 SMACPIVVAVIDQDFGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2908 FATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPN 2966
F S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2893 FYASGCVLSSACTMFTMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRFPE 2952
Query 2967 TYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNL 3026
EG VRVV T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L
Sbjct 2953 VLREGLVRVVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3027 LTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL 3086
+ +F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ VV N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSVVFVNVIVWC 3072
Query 3087 MSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYII 3146
++F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIA 3132
Query 3147 CISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ + H +W FS R++ + S TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVFS--YCRKLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSG 3265
YL+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3266 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKS 3325
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3326 NHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSP 3385
+ +F V + L V+ + M+ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMRGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3386 SGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFY 3445
G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3446 GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3505
GP+ D Q Q D +VN LAWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPIQDYIQSVNFLAWLYAAILNNCNWFIQSDKCSVEDFNVWALSNGFSQV 3488
Query 3506 TQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSG 3565
D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3566 VTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFA 3625
+ QS R KGT W++ + ++ +W++F ++ N F + + + A
Sbjct 3546 IKLQSKRTRLFKGTVCWIMASTFLFSCIITAFVKWTMFMYVTTNMF-SITFCALCVISLA 3604
Query 3626 MMFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
M+ VKHKH +L +++ P L T+ Y N +V ++ + WL S+ + D V+
Sbjct 3605 MLLVKHKHLYLTMYITPVLFTLLYNNYLVVYKHTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3685 YASAVVL-LILMTARTVYDD---GARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISV 3740
Y +++ ++ +T R++ D V L++V +L YK G+ L++ I + ++ S+
Sbjct 3664 YGMLLLVGMVFVTLRSINHDLFSFIMFVGRLISVFSLWYK---GSNLEEEILL--MLASL 3718
Query 3741 TSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLL 3800
Y+ M +A+ ++ V ++F ++ ++L Y F+GY +CY+GLF L+
Sbjct 3719 FGTYTWTTVLSMAVAK-VIAKWVAVNVLYFTDIPQIKIVLLCYLFIGYIISCYWGLFSLM 3777
Query 3801 NRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQS 3860
N FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QS
Sbjct 3778 NSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQS 3837
Query 3861 KMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLS 3920
K++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D + AFEK+ LL VL +
Sbjct 3838 KLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFEKLAQLLIVLFA 3897
Query 3921 MQGAVD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS- 3973
AVD I ++C++ + LQA+ SEF ++ S+ + A++ ++A +G +
Sbjct 3898 NPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARFSGSAN 3957
Query 3974 EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTML 4033
+ LK+L+K+ N+AKS ++RD A+ +KLE+MAD A+T MYK+AR DK++KV SA+QTML
Sbjct 3958 QQQLKQLEKACNIAKSAYERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTML 4017
Query 4034 FTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYAS 4093
F+M+RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA
Sbjct 4018 FSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTYAG 4077
Query 4094 ALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQ 4151
+W+IQ + D+D QL+EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4078 NVWQIQTIQDSDGTNKQLNEISDDCN----WPLVIIANRYNEVSATVLQNNELMPAKLKI 4133
Query 4152 MSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEP 4211
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+P
Sbjct 4134 QVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDP 4190
Query 4212 PCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCA 4271
PC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CA
Sbjct 4191 PCKFTVQDAKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCA 4250
Query 4272 FAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCR 4331
F+VD K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR
Sbjct 4251 FSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCR 4310
Query 4332 CHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPML 4391
++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +
Sbjct 4311 ARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCRVCGFWRDGSCSCVS-TDTTV 4368
Query 4392 QSADAQSFLN 4401
QS D +FLN
Sbjct 4369 QSKDT-NFLN 4377
Score = 80.9 bits (198), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 79/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K VK VVVN AN ++ HGGGVA A+ A E+ + + +
Sbjct 1273 ITPNVCFVKGDIIKVSKLVKAEVVVNPANGHMVHGGGVAKAIAVAAGQQFVKETTNMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++FN ++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYVLLERVYKHFNNYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T + V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFD 1425
Score = 63.5 bits (153), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 63/242 (26%), Positives = 103/242 (43%), Gaps = 30/242 (12%)
Query 715 GLYRKCVKSRE----ETGLL----MPL------------KAPKEIIFLEGETLPTEVLTE 754
G R C+ R+ E GLL +PL KA ++ I+L+G +
Sbjct 732 GRRRICLSGRKIYEVERGLLHSSQLPLDVYDLTMPSQVQKAKQKPIYLKGSGSDFSLADS 791
Query 755 EVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFT 814
V + T L P E P V +CI + + + Y + + + +
Sbjct 792 VVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDDHVGLLDQAW 846
Query 815 LKGGAPTKVTFGDD-TVIEVQGY-KSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFA 872
A +VTF + TV E+ K + + +ELD + +LN C + V+ ++ EF
Sbjct 847 RVPCAGRRVTFKEQPTVKEIISMPKIIKVFYELDNDFNTILNTACGVFEVDDTVDMEEFY 906
Query 873 CVVADAVIKTLQPVSELL---TPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDE 929
VV DA+ + L P EL + L + +LFDE+GE A +YC+F P++
Sbjct 907 AVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNPLFLFDEAGEEVFAPKLYCAFTAPED 966
Query 930 DE 931
D+
Sbjct 967 DD 968
>sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=1a PE=3 SV=1
Length=4383
Score = 1859 bits (4815), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1067/2887 (37%), Positives = 1628/2887 (56%), Gaps = 127/2887 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + + D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTV--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLK-PVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
D K P +++ ++K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAKEPKEINIIKLSGVKKPF--------KVEDSVIVNDDTSEIKYVKSLSIVDVYDMWL 2079
Query 2101 DNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNI 2156
++ N LSR + + T+ G+ V S+P D + KP N VV N
Sbjct 2080 TGCRCVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNK 2137
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
++ C N ++ + F LL + K T +A + + +F
Sbjct 2138 ISACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFL 2188
Query 2217 YLKSPNFSKLINII--IWFLLLSVCLGSLIYSTAALGVLMSNLG-MPSYCTGYREGYLNS 2273
K ++ II I+ L + ++I+S L +G +P++ + N+
Sbjct 2189 TFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYL----PKIGFLPTFVGKIAQWIKNT 2244
Query 2274 TN-VTIA------------TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTA 2320
+ VTI YC GSI C CL+G D LD Y +++ +Q ++ D A
Sbjct 2245 FSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRA 2299
Query 2321 F-------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINL 2371
F +V E ++Y L+T +FY L +Q+ ++ F+ ++ W + L+++L
Sbjct 2300 FVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSL 2359
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
M P +R YI ASF ++ + HV GC+ S C+ CYKRNR+ RV+C+TIV G+
Sbjct 2360 ANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMI 2419
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R + ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2420 RYYDAMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTV 2479
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEE 2551
V + L++D+ GQ+TY+ + S FV+ NL + K ++V+V + + ++
Sbjct 2480 TDVKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DK 2537
Query 2552 SSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKT 2611
++ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L
Sbjct 2538 ANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNA 2597
Query 2612 LVATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSC 2670
L+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SC
Sbjct 2598 LIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESC 2657
Query 2671 NNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIR 2730
NN + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2658 NNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLK 2717
Query 2731 SAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLI 2790
A K L KLT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2718 KACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLV-CFIG--LWCL 2774
Query 2791 TPVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTN 2847
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2775 MPTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2848 DKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTD 2907
ACP++ AV+ ++ G V +P +LR LHF+ SA G CYTP I Y++
Sbjct 2834 SMACPIVVAVVDQDFGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2908 FATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPN 2966
F S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+FP
Sbjct 2893 FYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRFPE 2952
Query 2967 TYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNL 3026
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L
Sbjct 2953 VLREGLVRIVRTRSMPYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3027 LTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL 3086
+ +F L QP+ L ++AS +AG I+A++V + YY ++ +RAFG+Y+ +V N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWC 3072
Query 3087 MSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYII 3146
++F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIS 3132
Query 3147 CISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ + H +W FS R++ + S TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVFS--YCRQLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSG 3265
YL+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3266 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKS 3325
KM P+ KVE C+V VT G TLNGLWL D VYCPRHVIC++ DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCIVSVTYGNMTLNGLWLGDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3326 NHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSP 3385
+ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3386 SGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFY 3445
G + MR ++TIKGSFL GSCGSV + I DCV F YMH +EL TG H GTD G+FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVVYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3446 GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3505
GP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQV 3488
Query 3506 TQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSG 3565
D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKH-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3566 VTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFA 3625
+ QS R +KG W++ + ++ +W++F ++ N L + + +
Sbjct 3546 IKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLT 3604
Query 3626 MMFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
M+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+
Sbjct 3605 MLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3685 YASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSN 3743
Y +++ ++ +T R++ + + V+++V Y G+ L++ I + ++ S+
Sbjct 3664 YGMLLLIGMVFVTLRSINQYLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGT 3721
Query 3744 YSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
Y+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N
Sbjct 3722 YTWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSL 3780
Query 3804 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMS 3863
FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++
Sbjct 3781 FRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLT 3840
Query 3864 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3923
DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL +
Sbjct 3841 DVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPA 3900
Query 3924 AVD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVV 3976
AVD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + +
Sbjct 3901 AVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQ 3960
Query 3977 LKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTM 4036
LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M
Sbjct 3961 LKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSM 4020
Query 4037 LRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALW 4096
+RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W
Sbjct 4021 VRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVW 4080
Query 4097 EIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSC 4154
+IQ + D+D QL EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4081 QIQTIQDSDGTNKQLHEISDDCN----WPLVIIANRHNEVSATALQNNELMPAKLKTQVV 4136
Query 4155 AAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCR 4214
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+
Sbjct 4137 NSGPDQTCNTPTQ--CYYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCK 4193
Query 4215 FVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAV 4274
F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+V
Sbjct 4194 FTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSV 4253
Query 4275 DAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHI 4334
D K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR +
Sbjct 4254 DPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCRARV 4313
Query 4335 DHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA 4394
+HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS
Sbjct 4314 EHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSK 4371
Query 4395 DAQSFLN 4401
D +FLN
Sbjct 4372 DT-NFLN 4377
Score = 84.3 bits (207), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T + V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFD 1425
Score = 71.2 bits (173), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 224/1007 (22%), Positives = 373/1007 (37%), Gaps = 179/1007 (18%)
Query 69 VFIKRS---DARTAPHGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL-- 122
+F +RS R A + HV +L + + G+ +G +G+ +G ++P + +PV RK +
Sbjct 130 LFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVP 187
Query 123 ----LRKNGNKGA-------GGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTR 171
LRK G KGA GG + + K D D + +P F +
Sbjct 188 WVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKK---------AY 238
Query 172 ELMRELNGGAYTRYVDNNFC---GPDGYPLECIKDLLARAGKASCTL-SEQLDFIDTKRG 227
L+R G YVD C G LE D + KA + S++L F
Sbjct 239 ALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPF------ 292
Query 228 VYCCREHEHEIAWYTERSEK-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPL 277
+ +AW+ R + LQ+ I+ D +G P V+
Sbjct 293 -------DVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYAD 345
Query 278 NSIIKTIQPRVEKKKLDGFM--------GRIRSVYPVASPNECNQMCLSTLMKC--DHCG 327
+SII + + L M + + Y V +C + + C D C
Sbjct 346 DSII------LRQHNLVDIMSCFYMEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCD 398
Query 328 ETSWQTGDFVKA-TCEFCGTENLTKEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLA 385
W G+ + C CG T + A + G LP N V+ A + G + S
Sbjct 399 FKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFT 457
Query 386 EYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI----GCNHTGVVGE 441
Y G + FGGCV+ + N W+P +++ G +TGVVG
Sbjct 458 LY------------GQTVVYFGGCVY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGC 501
Query 442 GSEGLNDNLL-EILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFK 500
+ NL+ + L + V + G+ E + + S L+ +K
Sbjct 502 KAIVKETNLICKALYLDYVQ-HKCGNLHQRELLGV---------SDVWHKQLLLNRGVYK 551
Query 501 QIVESCGNFKVTKGKAKKGAWNI---GEQKSILSPLY-----------AFASEAARVVRS 546
++E+ F + + K + + G +L L AF A ++ +
Sbjct 552 PLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYAGKICHA 611
Query 547 IFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVV 606
+ S++ E S+ L AAI L+ +++D SD T+ +V
Sbjct 612 VVSKSKELLDVSLDSL-GAAIHYLNS------KIVDLAQHFSDFGTS-------FVSKIV 657
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+ T+ L VL + + F+++ I ++ S V +
Sbjct 658 HFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKN---IPRYASA-----VAQAFRS 709
Query 667 CAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREE 726
AK + +S++ F + I + G+K+ + G + HS L +
Sbjct 710 VAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERG---LLHSSQL------PLDV 760
Query 727 TGLLMP---LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPV 783
L MP K ++ I+L+G + V + T L P E P V +
Sbjct 761 YDLTMPSQVQKTKQKPIYLKGSGSDFSLADSVVEVVTTSLTPCGYS-----EPPKVADKI 815
Query 784 CINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGY-KSVNI 841
CI + + + Y + + + A VTF + TV E+ K++ +
Sbjct 816 CIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRCVTFKEQPTVNEIASTPKTIKV 875
Query 842 TFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPLGIDLD 898
+ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTED---DY 955
+ + +LFDE+GE LA +YC+F P++D D EE E D
Sbjct 936 KLEDNSLFLFDEAGEEVLAPKLYCAFTAPEDD----DFLEESGVEEDDVEGEETDLTVTS 991
Query 956 QGKPLEFGATSAALQPEEEQE--EDWLDDDSQQTVGQQDGSEDNQTT 1000
G+P A + EE E ED LDD ED Q +
Sbjct 992 AGEP------CVASEQEESSEILEDTLDDGPCVETSDSQVEEDVQMS 1032
>sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=1a PE=3 SV=1
Length=4383
Score = 1858 bits (4812), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1066/2887 (37%), Positives = 1626/2887 (56%), Gaps = 127/2887 (4%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ + TVD +N + V + ++G+ G + DG +VTK K +++GK F+ N +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
++A D L Y + L + KW+ + K A+NNC++ + L LQ +
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLN 1684
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G A F +L+LA G+ D R+ + +F +L
Sbjct 1685 LKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
+ CK CG +Q GV+AVM+ GTLS E + G + C+CGK+ + V+ + PF++
Sbjct 1745 FEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S PA +L G + A+ + G+ + GHY H+ +++ D + + K ++ G ++D
Sbjct 1803 SNTPASVKLPKGVGS-ANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCL 1860
Query 1868 YKENSYTTTIKPV--TYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNAS 1924
Y +N T K V TY LD V E P L YY Y+T++ I +
Sbjct 1861 YLKN-LKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1925 FDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK + + D LN G+ E KVT +P GDVV Y +++G
Sbjct 1920 YTNFKLIGHTV--CDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGC 1977
Query 1984 KLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC 2041
KP++W H + N TY ++ + N FDVLK +D +++
Sbjct 1978 ITFGKPVIWLSHEQASLNSLTY----------FNRPLLVDENKFDVLKVDDVDDGGDISE 2027
Query 2042 EDLK-PVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
D K P +++ ++K +V +I+ + +K + + D+ ++
Sbjct 2028 SDAKEPKEINIIKLSGVKKPF--------KVEDSVIVNDDTSEIKYVKSLSIVDVYDMWL 2079
Query 2101 DNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTI-ANYAKPFLNKVVSTTTNI 2156
++ N LSR + + T+ G+ V S+P D + KP N VV N
Sbjct 2080 TGCRCVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVFN-VVKAVRNK 2137
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
++ C N ++ + F LL + K T +A + + +F
Sbjct 2138 ISACFN-----FIKWLFVLLFGWIKISADN----KVIYTTEVASKLTCKLVALAFKNAFL 2188
Query 2217 YLKSPNFSKLINII--IWFLLLSVCLGSLIYS---TAALGVLMSNLG-----------MP 2260
K ++ II I+ L + ++I+S +G L + +G +
Sbjct 2189 TFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIVQWIKNTFSLV 2248
Query 2261 SYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTA 2320
+ C Y + N YC GSI C CL+G D LD Y +++ +Q ++ D A
Sbjct 2249 TICDLYSIQDVGFKN----QYCNGSIACQFCLAGFDMLDNYKAIDVVQ-----YEADRRA 2299
Query 2321 F-------GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINL 2371
F +V E ++Y L+T +FY L +Q+ ++ + ++ W + L+++L
Sbjct 2300 FVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELLMLSTLHWSVRLLVSL 2359
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
M P +R YI ASF ++ + HV GC+ S C+ CYKRNR+ RV+C+TIV G+
Sbjct 2360 ANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMI 2419
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2420 RYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTV 2479
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEE 2551
V + L++D+ GQ+TY+ + S FV+ NL + K ++V+V + + ++
Sbjct 2480 TDVKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DK 2537
Query 2552 SSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKT 2611
++ +A+V+Y+Q + +PIL++D+ L++ V MFD YV+TF S F+V + L
Sbjct 2538 ANFLNAAVFYAQSLFRPILMVDKILITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNA 2597
Query 2612 LVATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSC 2670
L+ATA + + + + VL TF+S AR+ +DSDV+TK + + + + + +E+T +SC
Sbjct 2598 LIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESC 2657
Query 2671 NNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIR 2730
NN + TY K +N+ DLG I SA+H+ VAK ++ IW+V F LS + +++
Sbjct 2658 NNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLK 2717
Query 2731 SAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLI 2790
A K L +LT V+V+TT +LKGG + + ++ ++LV F+ + +
Sbjct 2718 KACCKTGLKLELTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLV-CFIG--LWCL 2774
Query 2791 TPVHVMSKHTDFSSEIIG-YKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTN 2847
P + + K +DF + YK +D GV RD++ D CFANK FD W+ G Y+N
Sbjct 2775 MPTYTVHK-SDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2848 DKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTD 2907
ACP++ AV+ ++ G V +P +LR LHF+ SA G CYTP I Y++
Sbjct 2834 SMACPIVVAVVDQDFGSTVFNVPTKVLRY-GYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2908 FATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDG-SIIQFPN 2966
F S CVL++ CT+F A G P PYCY +++ + Y SL P RY L + I+ P
Sbjct 2893 FYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRLPE 2952
Query 2967 TYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNL 3026
EG VR+V T YCR G CE ++ G+C + +G WVLNNDYYRSLPG FCG D +L
Sbjct 2953 VLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3027 LTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL 3086
+ +F L QP+ L ++AS +AG I+A++V YY ++ +RAFG+Y+ +V N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLGFYYLIKLKRAFGDYTSIVFVNVIVWC 3072
Query 3087 MSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYII 3146
++F +L + VY L VY++ Y Y T Y +++S + H+QW+VM+ ++P W + YI
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIS 3132
Query 3147 CISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ + H +W FS R++ + S TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVFS--YCRQLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS-GSDVLYQPPQTSITSAVLQSG 3265
YL+LYNKY+Y+SG MDT +YREAAC LAKA++ F+N+ GSDVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3266 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKS 3325
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC++ DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3326 NHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSP 3385
+ +F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3386 SGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFY 3445
G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G+FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3446 GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3505
GP+ D Q Q D +VN +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQV 3488
Query 3506 TQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSG 3565
D V + L++ TG+++ + A++K L+NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3566 VTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFA 3625
+ QS R +KG W++ + ++ +W++F ++ N L + + + A
Sbjct 3546 IKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLA 3604
Query 3626 MMFVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
M+ VKHKH +L ++++P L T+ Y N +V ++ + WL S+ + D V+
Sbjct 3605 MLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3685 YASAVVL-LILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSN 3743
Y +++ ++ +T R++ D + + V+++V Y G+ L++ I + ++ S+
Sbjct 3664 YGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGT 3721
Query 3744 YSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
Y+ M A+ ++ V ++F ++ +++ Y F+GY +CY+GLF L+N
Sbjct 3722 YTWTTALSMAAAK-VIAKWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSL 3780
Query 3804 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMS 3863
FR+ LGVY+Y +S QE RYMN+ GL PPKNS +A LN KLLG+GG P I+V+ QSK++
Sbjct 3781 FRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLT 3840
Query 3864 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3923
DVKC + LL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL +
Sbjct 3841 DVKCANGGLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPA 3900
Query 3924 AVD------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVV 3976
AVD I ++C++ + LQA+ SEF ++ S+ + A++ ++A ++G + +
Sbjct 3901 AVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQ 3960
Query 3977 LKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTM 4036
LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M
Sbjct 3961 LKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSM 4020
Query 4037 LRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALW 4096
+RKLDN ALN+I++NA GCVPLN IP A L +++PD + Y D TYA +W
Sbjct 4021 VRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVW 4080
Query 4097 EIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSC 4154
+IQ + D+D QL EIS D + WPL++ A R N SA LQNNEL P L+
Sbjct 4081 QIQTIQDSDGTNKQLHEISDDCN----WPLVIIANRHNEVSATVLQNNELMPAKLKTQVV 4136
Query 4155 AAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCR 4214
+G QT T YYN + G+ V A+LSD+ LK+ + K DG + EL+PPC+
Sbjct 4137 NSGPDQTCNTPTQ--CYYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCK 4193
Query 4215 FVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAV 4274
F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+V
Sbjct 4194 FTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSV 4253
Query 4275 DAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHI 4334
D K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR +
Sbjct 4254 DPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCRARV 4313
Query 4335 DHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA 4394
+HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS
Sbjct 4314 EHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSK 4371
Query 4395 DAQSFLN 4401
D +FLN
Sbjct 4372 DT-NFLN 4377
Score = 84.3 bits (207), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D + +
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNK--GEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + T + V L ++ +D
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFD 1425
Score = 63.2 bits (152), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 51/172 (30%), Positives = 76/172 (44%), Gaps = 18/172 (10%)
Query 837 KSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELL---TPL 893
K++ + +ELD+ + +LN C + V+ ++ EF VV DA+ + L P EL +
Sbjct 871 KTIKVFYELDKDFNTILNTACGEFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKV 930
Query 894 GIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTED 953
L + + +LFDE+GE LA +YC+F P++D D EE E D
Sbjct 931 SAFLQKLEDNSLFLFDEAGEEVLAPKLYCAFTAPEDD----DFLEESGVEEDDVEGEETD 986
Query 954 ---DYQGKPLEFGATSAALQPEEEQE--EDWLDDDSQQTVGQQDGSEDNQTT 1000
G+P A + EE E ED LDD ED Q +
Sbjct 987 LTVTSAGEP------CVASEQEESSEILEDTLDDGPCVETSDSQVEEDVQMS 1032
>sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus
(strain 2) OX=76344 GN=1a PE=3 SV=1
Length=4416
Score = 1834 bits (4751), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1084/2925 (37%), Positives = 1610/2925 (55%), Gaps = 163/2925 (6%)
Query 1549 EVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIK 1608
+V + ++ LL+ + V TVD +N + V +G+ G + DG +VTK++
Sbjct 1543 KVASVSQIRALLA----NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVR 1598
Query 1609 PHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIK 1668
H+GK F+ + A D L +Y + L K W + K
Sbjct 1599 CSAIHKGKVFFQYSGLSAADLVAVTDAFGFDEPQLLKYYNMLGMCK-WPVVVCGNYFAFK 1657
Query 1669 WADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDV 1728
++NNCY+ A L LQ + LKF+ Q+A+ R+G+ F +L+LA + E D
Sbjct 1658 QSNNNCYINVACLMLQHLSLKFHKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDS 1717
Query 1729 RETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCT 1788
+ M + + A+L VCK CG +Q KGV+AVM+ GTL KG I CT
Sbjct 1718 TDFMRVVLREADLSGATCDFEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLAKGYTIACT 1776
Query 1789 CGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCI 1848
CG + + Q PF++ S P +L A+ +TG GHY H+ K
Sbjct 1777 CGNKLV-HCTQLNVPFLICSNKPEGKKLPDDVVA-ANIFTGG-SLGHYTHVKCKPKYQLY 1833
Query 1849 DGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYF 1907
D ++K SE KG TD Y +N T + K T+ LD V C E +P L YY + Y+
Sbjct 1834 DACNVSKVSEAKGNFTDCLYLKNLKQTFSSKLTTFYLDDVKCVEYNPDLSQYYCESGKYY 1893
Query 1908 TEQPIDLVPNQPYPNAS--FDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLN 1964
T +PI + + + NFK V +I A+ N G+ E K+T +P
Sbjct 1894 T-KPIIKAQFRTFEKVEGVYTNFKLVGHSI--AEKFNAKLGFDCNSPFTEYKITEWPTAT 1950
Query 1965 GDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVE 2020
GDVV Y + G KP++W H + TY +P+ C ++ PV+
Sbjct 1951 GDVVLASDDLYVSRYSGGCVTFGKPVIWLGHEEASLKSLTYFNRPSVVC-ENKFNVLPVD 2009
Query 2021 TSNSFD-------VLKSEDAQG---MDNLACEDLKPVSEEVVEN---------PTIQKDV 2061
S D VL + G A E S+ VV+ DV
Sbjct 2010 VSEPTDKGPVPAAVLVTGALSGAATAPGTAKEQKVCASDSVVDQVVSGFLSDLSGATVDV 2069
Query 2062 LECNV----KTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVL 2117
E + K +V +++ + K+ + + D+ ++ + NELSR+
Sbjct 2070 KEVKLNGVKKPIKVEDSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWMANELSRL- 2128
Query 2118 GLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNR-------------V 2164
VNS T+ Y K + K+V ++ R +
Sbjct 2129 ------------VNS---PTVREYVKWGMTKIVIPAKLVLLRDEKQEFVAPKVVKAKVIA 2173
Query 2165 CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFS 2224
C + + +FF F N+ K T +A K C A N L++ N++
Sbjct 2174 CYSAVKWFFLYCFSWIKF----NTDNKVIYTTEVAS---KLTFNLCCLAFKNALQTFNWN 2226
Query 2225 KLIN--------IIIWF-------LLLSVCLGSLIYSTAALGVLMS----NLGMPSYCTG 2265
+ ++WF +L L ++ + +G +++ G+ + C
Sbjct 2227 VVSRGFFLVATVFLLWFNFLYANVILSDFYLPNIGFFPTFVGQIVAWVKTTFGIFTLCDL 2286
Query 2266 YR---EGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLT 2319
Y+ GY +S +C GS+ C +C SG D LD Y ++ +Q + SF + ++
Sbjct 2287 YQVSDVGYRSS-------FCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRVSFDY-IS 2338
Query 2320 AFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPI 2377
F LV E + Y L+T FY L MQL ++ F+ + W + + M P
Sbjct 2339 LFKLVVELVIGYSLYTVCFYPLFGLIGMQLLTTWLPEFFMLETMHWSARFFVFVANMLPA 2398
Query 2378 SAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVY 2437
++R YI + Y ++ HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V
Sbjct 2399 FTLLRFYIVVTAMYKIFCLCRHVMYGCSRPGCLFCYKRNRSVRVKCSTVVGGTLRYYDVM 2458
Query 2438 ANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVK 2497
ANGG GFC H WNC+NC F G+TFI+ E A DLS + KRP+NPTD + Y+V V
Sbjct 2459 ANGGTGFCAKHQWNCLNCSAFGPGNTFITHEAAADLSKELKRPVNPTDSAYYLVTEVKQV 2518
Query 2498 NGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSA 2557
S+ L++++ GQ+ Y+ S S FV+++ L + KG +V+V + ++ +++ +A
Sbjct 2519 GCSMRLFYERDGQRVYDDVSASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNA 2576
Query 2558 SVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAE 2617
+V+Y+Q + +P+LL+++ L++ V+ MFD YV++ +V + L + V A
Sbjct 2577 AVFYAQSLYRPMLLVEKKLITTANTGLSVSQTMFDLYVDSLLGVLDVDRKSLTSFVNAAH 2636
Query 2618 AELAKNVSLDNVLSTFISAARQG-FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLT 2676
L + V L+ V+ TFI AR+ +DSDVETK + + + + + ++ T +SCNN + T
Sbjct 2637 NSLKEGVQLEQVMDTFIGCARRKCAIDSDVETKSITKSIMSAVNAGVDFTDESCNNLVPT 2696
Query 2677 YNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKN 2736
Y K + + DLG I +A+H+ A VAK+ N+A IW+V F LS L+ ++R A K
Sbjct 2697 YVKSDTIVAADLGVLIQNNAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKT 2756
Query 2737 NLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVM 2796
L KLT V ++TT +LKGG + + L+ L V L+ V + + P + +
Sbjct 2757 GLKIKLTYNKQEANVPILTTPFSLKGGAVFSKVLQWLFVVNLICFIV---LWALMPTYAV 2813
Query 2797 SKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLI 2854
K +K ID GV RD+ TD CFANK FD W+ G Y N +ACP++
Sbjct 2814 HKSDMQLPLYASFKVIDNGVLRDVTVTDACFANKFIQFDQWYESTFGLVYYRNSRACPVV 2873
Query 2855 AAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACV 2914
AVI +++G+ + +P +LR LHF+ F+ CYTP I Y +F S CV
Sbjct 2874 VAVIDQDIGYTLFNVPTKVLR-YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCV 2932
Query 2915 LAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSV 2973
L++ CT+ A G P PYCY ++ + Y+SL P RY L + + I+FP EG V
Sbjct 2933 LSSLCTMLAHADGTPHPYCYTEGIMHNASLYDSLAPHVRYNLANSNGYIRFPEVVSEGIV 2992
Query 2974 RVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTP 3033
R+V T YCR G CE +E GVC + + WVLNN YYR++PG FCG +A +L+ +
Sbjct 2993 RIVRTRSMTYCRVGLCEDAEEGVCFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGG 3052
Query 3034 LIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLC 3093
L++PI ++AS VAG I+AI+V YY ++ +RAFG+Y+ VV N +++ ++F +L
Sbjct 3053 LVRPIDFFALTASSVAGAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLF 3112
Query 3094 LTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHF 3153
+ VY L +Y+ Y Y T Y +++S + H+QW+VM+ ++P W I Y+ + + H
Sbjct 3113 VFQVYPTLSCLYACFYFYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHA 3172
Query 3154 YWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNK 3213
W FS R++ S TFEE +L TF++ KE Y KL++ V +NRYL+LYNK
Sbjct 3173 LWLFS--YCRKLGTEVRSDGTFEEMSLTTFMITKESYCKLKNSV--SDVAFNRYLSLYNK 3228
Query 3214 YKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFP 3272
Y+YFSG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S+T++ LQSG KM FP
Sbjct 3229 YRYFSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVFP 3288
Query 3273 SGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQ 3332
+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R + +F V
Sbjct 3289 TSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYSNLLCRVISSDFCVM 3348
Query 3333 AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCA 3392
+G + L V+ + MQ +L L V NP TPKY F ++PG+TF+VLA YNG G +
Sbjct 3349 SGRMSLTVMSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGKSQGAFHVT 3408
Query 3393 MRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQ 3452
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+ D Q
Sbjct 3409 MRSSYTIKGSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQ 3468
Query 3453 TAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDI 3512
Q D T TVNV+AWLYAA++N WF+ + +L +FN+ AM + + D V
Sbjct 3469 VVQLPVQDYTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV-- 3526
Query 3513 LGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAV 3572
L L++ TG+ V + A++K L +G G+ ILGS +LEDE TP DV +Q +GV QS
Sbjct 3527 LDALASMTGVTVEQILAAIKRLY-SGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKR 3585
Query 3573 KRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHK 3632
R +KGT W+L + L ++ +W++F ++ + L + + +FAM+ VKHK
Sbjct 3586 TRVVKGTCCWILASTLLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLVKHK 3644
Query 3633 HAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL 3691
H +L +F++P L T+ Y N +V S+ WL ++ + D V+Y VVL
Sbjct 3645 HLYLTMFIMPVLCTLFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLY--GVVL 3701
Query 3692 LILM---TARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
L+ M T R++ D ++ + +++LV Y+G L++ + ++ + S+ Y+
Sbjct 3702 LVAMVFVTMRSINHDVFSVMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW-- 3757
Query 3749 TTVMFLARG-IVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
TT++ LA ++ + ++F ++ ++L Y +GY C CY+G+ LLN FR+
Sbjct 3758 TTMLSLATAKVIAKWLAVNVLYFTDVPQVKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMP 3817
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
LGVY+Y +S QE RYMN+ GL PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC
Sbjct 3818 LGVYNYKISVQELRYMNANGLRPPRNSFEALVLNFKLLGIGGVPVIEVSQIQSRLTDVKC 3877
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD- 3926
+VVLL+ LQ L + SSSKLW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3878 VNVVLLNCLQHLHIASSSKLWQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDS 3937
Query 3927 -----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKL 3980
I ++ ++ + + LQA+ SEF ++ S+ + A++ ++A A+G + + +K+L
Sbjct 3938 KCLASIEEVSDDYVRDSTVLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQL 3997
Query 3981 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4040
+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKL
Sbjct 3998 EKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKL 4057
Query 4041 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQ 4100
DN ALN+I++NA GCVPLN IP T+ L +++PD + D TYA +W IQ
Sbjct 4058 DNQALNSILDNAVKGCVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQS 4117
Query 4101 VVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGT 4158
+ DAD + QL+EI + N+ WPL++ A R N S+V LQNNEL P LR +G+
Sbjct 4118 IQDADGAVKQLNEIDV----NITWPLVIAANRHNEVSSVVLQNNELMPQKLRTQVVNSGS 4173
Query 4159 TQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTD 4218
T YYNTT G+ V A+LSD LK+ + K DG + EL+PPC+F
Sbjct 4174 DMNCNTPTQ--CYYNTTGMGKIVYAILSDCDGLKYTKIVKEDGN-CVVLELDPPCKFSVQ 4230
Query 4219 TPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK 4278
KG K+KYLYF+KG N L RG V+G+L++TVRLQAG ATE +NS + S CAF+VD K
Sbjct 4231 DVKGLKIKYLYFVKGCNTLARGWVVGTLSSTVRLQAGTATEYASNSAIRSLCAFSVDPKK 4290
Query 4279 AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPN 4338
Y DY+ GG P+TNCVKMLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+
Sbjct 4291 TYLDYIQQGGAPVTNCVKMLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPD 4350
Query 4339 PKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSC 4383
G C L+GK+VQ+P DPV + L + VC VCG W+ CSC
Sbjct 4351 VDGLCKLRGKFVQVPLG-IKDPVSYVLTHDVCQVCGFWRDGSCSC 4394
Score = 72.0 bits (175), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 60/183 (33%), Positives = 83/183 (45%), Gaps = 21/183 (11%)
Query 819 APTKVTFGDD-TVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVAD 877
A KV F D V E+ + + I F LD D VL++ CS + V+ ++E VV D
Sbjct 832 AGKKVEFNDKPKVKEIPSTRKIKINFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLD 891
Query 878 AVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEG 934
AV TL P E + T + L+ + YLFDE GE +A MYCSF PD++
Sbjct 892 AVESTLSPCKEHDVIGTKVCALLNRLAEDYVYLFDEGGEEVIAPKMYCSFSAPDDE---- 947
Query 935 DCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGS 994
DC + + + + DD SAAL + QEED + Q V + D
Sbjct 948 DCVAADVVDADENQGDDADD-----------SAALV-TDTQEEDGV-AKGQVGVAESDAR 994
Query 995 EDN 997
D
Sbjct 995 LDQ 997
Score = 59.3 bits (142), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 52/154 (34%), Positives = 82/154 (53%), Gaps = 4/154 (3%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV D+++ ++V V+VN AN + HG GVAGA+ KA + E+ D +
Sbjct 1267 ITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKSFIKETADMVKN 1326
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENFNQHEVLLAPLLS 1150
G +VG +G NL K L++VGP+ +G Q L+ AY++ N+ + ++ L+S
Sbjct 1327 QGVCQVGECYESTGGNLCKTVLNIVGPDA-RGHGKQCYSFLERAYQHINKCDDVVTTLIS 1385
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
AGIF SL + V NV L +K+ +D
Sbjct 1386 AGIFSVPTDVSLTYLIGVVTKNVILVSNNKDDFD 1419
Score = 41.2 bits (95), Expect = 0.58, Method: Compositional matrix adjust.
Identities = 84/343 (24%), Positives = 131/343 (38%), Gaps = 70/343 (20%)
Query 59 GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQYGRSGETLGVLVPHVGEI 114
GVLP+ +F + T HV +L + +G+ G +G +G VP V I
Sbjct 120 GVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCLG-NGRFIGWFVP-VTAI 177
Query 115 PVAYRK-------VLLRKNGNKG---AGGHSYGADLKSFDLGDELGTDPYEDFQENWNTK 164
P AY K +LLRK GNKG +G + +D E D E+ N K
Sbjct 178 P-AYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE---DACEEVHLNPKGK 233
Query 165 HSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDT 224
+S L++ G ++D C G + ++D CTL E +
Sbjct 234 YSRK-AYALLKGYRGVKSILFLDQYGCDYTGRLAKGLEDY------GDCTLEEMKELFP- 285
Query 225 KRGVYC-CREHEHEIAWYTERSEKS-YELQTPFEIKLAKKF-----DTFNGEC----PNF 273
V+C ++E +AW+ +R ++ LQT I+ D +G+ P
Sbjct 286 ---VWCDSLDNEVVVAWHVDRDPRAVMRLQTLATIRSIGYVGQPTEDLVDGDVVVREPAH 342
Query 274 VFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQT 333
+ N+I+K + PR+ + L Y +S E C T + CD T +
Sbjct 343 LLAANAIVKRL-PRLVETML----------YTDSSVTE---FCYKTKL-CDCGFITQFGY 387
Query 334 GDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNS 376
D C+F G++P N + CP C S
Sbjct 388 VDCCGDACDF-------------RGWVPGNMMDGFLCPGCSKS 417
>sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronavirus
(strain JHM) OX=11144 GN=1a PE=1 SV=1
Length=4474
Score = 1834 bits (4750), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1071/2905 (37%), Positives = 1597/2905 (55%), Gaps = 151/2905 (5%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ V TVD +N + V +G+ G + DG +VTK++ H+GK F+
Sbjct 1610 VDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIHKGKVFFQYSGLSAA 1669
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
+ A + D L +Y S L K W + K ++NNCY+ A L LQ +
Sbjct 1670 DLAAVKDAFGFDEPQLLQYYSMLGMCK-WPVVVCGNYFAFKQSNNNCYINVACLMLQHLS 1728
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF + R+G+ F +L+LA + E D + + + A+L
Sbjct 1729 LKFPKWQWRRPGNEFRSGKPLRFVSLVLAKGSFKFNEPSDSTDFIRVELREADLSGATCD 1788
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
L +CK CG +Q KGV+AVM+ GTL KG I CTCG + + Q PF++
Sbjct 1789 LEFICK-CGVKQEQRKGVDAVMHFGTLDKSGLVKGYNIACTCGDKLV-HCTQFNVPFLIC 1846
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S P +L A+ +TG GHY H+ K D ++K SE KG TD
Sbjct 1847 SNTPEGKKLPDDVVA-ANIFTGG-SVGHYTHVKCKPKYQLYDACNVSKVSEAKGNFTDCL 1904
Query 1868 YKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPNAS-- 1924
Y +N T + TY LD V C P L YY + Y+T +PI + +
Sbjct 1905 YLKNLKQTFSSVLTTYYLDDVKCVAYKPDLSQYYCESGKYYT-KPIIKAQFRTFEKVEGV 1963
Query 1925 FDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK V +I A+ LN G+ E K+T +P GDVV Y + G
Sbjct 1964 YTNFKLVGHDI--AEKLNAKLGFDCNSPFMEYKITEWPTATGDVVLASDDLYVSRYSGGC 2021
Query 1984 KLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVETSNSFD------------- 2026
KP++W H + TY +P+ C ++ PV+ S D
Sbjct 2022 VTFGKPVIWRGHEEASLKSLTYFNRPSVVC-ENKFNVLPVDVSEPTDRRPVPSAVLVTGA 2080
Query 2027 -------VLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVG------ 2073
+ +E + AC V +++V + V VK ++ G
Sbjct 2081 ASGADASAISTEPGTAKEQKACAS-DSVEDQIVMEAQKKSSVTTVAVKEVKLNGVKKPVK 2139
Query 2074 ---DIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATH---GL 2127
+++ + K+ + + D+ ++ + NELSR++ T+ + G+
Sbjct 2140 WNCSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWTANELSRLINSPTVREYVKWGM 2199
Query 2128 AAVNSVPWDTI--ANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRS 2185
+ + +P + + + + F+ V I C + +F F
Sbjct 2200 SKL-IIPANLLLLRDEKQEFVAPKVVKAKAIA-------CYGAVKWFLLYCFSWIKF--- 2248
Query 2186 TNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLIN--------IIIWF--LL 2235
N+ K T +A K K C A N L++ N+S + ++WF L
Sbjct 2249 -NTDNKVIYTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVFLLWFNFLY 2304
Query 2236 LSVCLGSL---------IYSTAALGVLMSNLGMPSYCTGYRE---GYLNSTNVTIATYCT 2283
+V L ++ + + + G+ + C Y+ GY +S +C
Sbjct 2305 ANVILSDFYLPNIGPLPMFVGQIVAWVKTTFGVLTICDFYQVTDLGYRSS-------FCN 2357
Query 2284 GSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
GS+ C +C SG D LD Y S+ +Q + SF + ++ F LV E + Y L+T FY
Sbjct 2358 GSMVCELCFSGFDMLDNYESINVVQHVVDRRVSFDY-ISLFKLVVELVIGYSLYTVCFYP 2416
Query 2341 LGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYV 2398
L + MQL ++ F+ + W L + + M P ++R YI + Y V+
Sbjct 2417 LFVLVGMQLLTTWLPEFFMLGTMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVYCLCR 2476
Query 2399 HVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTF 2458
HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC+NC+++
Sbjct 2477 HVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLNCNSW 2536
Query 2459 CAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSL 2518
G+TFI+ E A DLS + KRP+NPTD + Y V V S+ L++++ GQ+ Y+ S
Sbjct 2537 KPGNTFITHEAAADLSKELKRPVNPTDSAYYSVIEVKQVGCSMRLFYERDGQRVYDDVSA 2596
Query 2519 SHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVS 2578
S FV+++ L + KG +V+V + ++ +++ +A+V+Y+Q + +P+L++++ L++
Sbjct 2597 SLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRPMLMVEKKLIT 2654
Query 2579 DVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAAR 2638
V+ MFD YV + +V + L + V A L + V L+ V+ TF+ AR
Sbjct 2655 TANTGLSVSRTMFDLYVYSLLRHLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFVGCAR 2714
Query 2639 QG-FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSAR 2697
+ +DSDVETK + + + + + +EVT +SCNN + TY K + + DLG I +A+
Sbjct 2715 RKCAIDSDVETKSITKSVMAAVNAGVEVTDESCNNLVPTYVKSDTIVAADLGVLIQNNAK 2774
Query 2698 HINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTK 2757
H+ + VAK+ N+A IW+V F LS L+ ++R A K L KLT V ++TT
Sbjct 2775 HVQSNVAKAANVACIWSVDAFNQLSADLQHRLRKACVKTGLKIKLTYNKQEANVPILTTP 2834
Query 2758 IALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVT 2817
+LKGG + + L+ L L+ V + + P + + K +K ID GV
Sbjct 2835 FSLKGGAVFSRVLQWLFVANLICFIV---LWALMPTYAVHKSDMQLPLYASFKVIDNGVL 2891
Query 2818 RDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILR 2875
RD++ TD CFANK FD W+ G Y N KACP++ AVI +++G + +P +LR
Sbjct 2892 RDVSVTDACFANKFNQFDQWYESTFGLVYYRNSKACPVVVAVIDQDIGHTLFNVPTKVLR 2951
Query 2876 TTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYD 2935
LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P PYCY
Sbjct 2952 Y-GFHVLHFITHAFATDRVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHPYCYT 3010
Query 2936 TNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEA 2994
V+ + Y SL P RY L + I+FP EG VRVV T YCR G CE +E
Sbjct 3011 EGVMHNASLYSSLVPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLCEEAEE 3070
Query 2995 GVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVA 3054
G+C + + WVLNN YYR++PG FCG +A +L+ + L+QPI ++AS VAG I+A
Sbjct 3071 GICFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVQPIDFFALTASSVAGAILA 3130
Query 3055 IVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTF 3114
I+V YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L +Y+ Y Y T
Sbjct 3131 IIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFYTTL 3190
Query 3115 YLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFST 3174
Y +++S + H+QW+VM+ ++P W I Y+ + + H W FS R++ + S T
Sbjct 3191 YFPSEISVVMHLQWLVMYGAIMPLWFCITYVAVVVSNHALWLFS--YCRKIGTDVRSDGT 3248
Query 3175 FEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL 3234
FEE AL TF++ KE Y KL++ V +NRYL+LYNKY+YFSG MDT +YREAAC L
Sbjct 3249 FEEMALTTFMITKESYCKLKNSV--SDVAFNRYLSLYNKYRYFSGKMDTATYREAACSQL 3306
Query 3235 AKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
AKA+ F+ N+G+DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G TLNGL
Sbjct 3307 AKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCVVSVTYGNMTLNGL 3366
Query 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
WLDD VYCPRHVIC+S DM +P+Y +LL R ++ +F V + + L V+ + MQ +L L
Sbjct 3367 WLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSDRMSLTVMSYQMQGSLLVLT 3426
Query 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
V NP TPKY F ++PG+TF+VLA YNG P G + MR + TIKGSFL GSCGSVG+
Sbjct 3427 VTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVVMRSSHTIKGSFLCGSCGSVGY 3486
Query 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
+ D V F YMH +EL TG H GTD GNFYGP+ D Q Q D T TVNV+AWLYA
Sbjct 3487 VLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAWLYA 3546
Query 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
A++N WF+ + +L +FN+ AM + + D V L L++ TG+ V + A++K
Sbjct 3547 AILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVLAAIKR 3604
Query 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
L +G G+ ILGS +LEDE TP DV +Q +GV QS R IKGT W+L + +
Sbjct 3605 -LHSGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTFLFCSI 3663
Query 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
+ +W++F ++ + L + + FAM+ +KHKH +L ++++P L T+ Y N +
Sbjct 3664 ISAFVKWTMFMYVTTH-MLGVTLCALCFVIFAMLLIKHKHLYLTMYIMPVLCTLFYTNYL 3722
Query 3654 YMPASWVMRIM--TWLDMVDTSLSGFKLKDCVMYASAVVLLILM---TARTVYDDGARRV 3708
+ R + WL ++ + D V+Y VVLL+ M T R++ D +
Sbjct 3723 VVGYKQSFRGLAYAWLSYFVPAVD-YTYMDEVLY--GVVLLVAMVFVTMRSINHDVFSTM 3779
Query 3709 WTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARG-IVFMCVEYCP 3767
+ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA ++ +
Sbjct 3780 FLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKWLAVNV 3835
Query 3768 IFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQG 3827
++F ++ ++L Y +GY C CY+G+ LLN FR+ LGVY+Y +S QE RYMN+ G
Sbjct 3836 LYFTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISVQELRYMNANG 3895
Query 3828 LLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKL 3887
L PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+SKL
Sbjct 3896 LRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNSKL 3955
Query 3888 WAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATL 3941
W C LHN+IL D + AF+K+ LL VL + AVD I ++ ++ + + L
Sbjct 3956 WQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNTVL 4015
Query 3942 QAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRK 4000
QA+ SEF ++ S+ + A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ RK
Sbjct 4016 QALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARK 4075
Query 4001 LEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLN 4060
LE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN
Sbjct 4076 LERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLN 4135
Query 4061 IIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSP 4120
IP T+ L +++PD + D TYA +W IQ + DAD + QL+EI ++++
Sbjct 4136 AIPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDVNST- 4194
Query 4121 NLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGG 4178
WPL+++A R N S V LQNNEL P LR +G+ + YYNTT G
Sbjct 4195 ---WPLVISANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNC--NIPTQCYYNTTGTG 4249
Query 4179 RFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLN 4238
+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L
Sbjct 4250 KIVYAILSDCDGLKYTKIVKEDGN-CVVLELDPPCKFSVQDVKGLKIKYLYFVKGCNTLA 4308
Query 4239 RGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKML 4298
RG V+G+L++TVRLQAG ATE +NS +LS CAF+VD K Y DY+ GG P+TNCVKML
Sbjct 4309 RGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIQQGGVPVTNCVKML 4368
Query 4299 CTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCAN 4358
C H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P
Sbjct 4369 CDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-IK 4427
Query 4359 DPVGFTLKNTVCTVCGMWKGYGCSC 4383
DPV + L + VC VCG W+ CSC
Sbjct 4428 DPVSYVLTHDVCQVCGFWRDGSCSC 4452
Score = 88.2 bits (217), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 239/1025 (23%), Positives = 394/1025 (38%), Gaps = 219/1025 (21%)
Query 2 ESLVPGFNEKTHVQLS---LPVLQ-------VRDVLVRGFGDSVEEVLSEARQHLKDGTC 51
E V G HV++ LP L+ +RD+ V + ++V + L+ G+
Sbjct 46 EPKVKGKTLVNHVRVDCSRLPALECCVQSAIIRDIFV---DEDPQKVEASTMMALQFGSA 102
Query 52 GLVEVEK----------GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQY 97
LV+ K GVLP+ +F + T HV +L + +G+
Sbjct 103 VLVKPSKRLSVQAWAKLGVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCL 162
Query 98 GRSGETLGVLVPHVGEIPVAYRK------VLLRKNGNKGA---GGHSYGADLKSFDLGDE 148
G +G +G VP V IP ++ +LLRK GNKG+ G + +D E
Sbjct 163 G-NGRFIGWFVP-VTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE 220
Query 149 LGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARA 208
D E+ N K+S L+R G +VD C G C+ L
Sbjct 221 ---DACEEVHLNPRGKYSCK-AYALLRGYRGVKPILFVDQYGCDYTG----CLAKGLEDY 272
Query 209 GKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKS-YELQTPFEIKLAKKF---- 263
G TLSE + R ++E +AW+ +R ++ LQT ++ +
Sbjct 273 GDL--TLSEMKELSPVWRDSL---DNEVVVAWHVDRDPRAVMRLQTLATVRSIEYVGQPI 327
Query 264 -DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLS 318
D +G+ P + N+I+K + PR+ + L Y +S E C
Sbjct 328 EDMVDGDVVMREPAHLLAPNAIVKRL-PRLVETML----------YTDSSVTE---FCYK 373
Query 319 TLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPAC----- 373
T + CD CG + Q G +V + CG G++P N + CP C
Sbjct 374 TKL-CD-CGFIT-QFG-YVDCCGDTCGFR----------GWVPGNMMDGFPCPGCCKSYM 419
Query 374 ------HNSEVGPEHSL--AEYHNESGLKTILRKGGRTIAFGGCVF--SYVGCHNKCAYW 423
+S V PE + + + ++ G + FGG + Y G W
Sbjct 420 PWELEAQSSGVIPEGGVLFTQSTDTVNRESFKLYGHAVVPFGGAAYWSPYPG------MW 473
Query 424 VPRASANIGC----NHTGVVG-EGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILA 478
+P +++ +TGVVG + D + L + V + G+ E+ AI+
Sbjct 474 LPVIWSSVKSYSYLTYTGVVGCKAIVQETDAICRFLYMDYVQ-HKCGNL---EQRAIL-- 527
Query 479 SFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFAS 538
GLD +Q++ + G++ + +L + F
Sbjct 528 --------------GLDDVYHRQLLVNRGDYSL-----------------LLENVDLFVK 556
Query 539 EAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA-MMFTSDLATNNLVV 597
R+ F+ T + + L +LDG+ S LI + FTS + + V
Sbjct 557 R-----RAEFACKFATCGDGLVPL------LLDGLVPRSYYLIKSGQAFTSLMVNFSREV 605
Query 598 ------MAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRD------G 645
MA + V++ ++++ + G V + K + + K E + D G
Sbjct 606 VDMCMDMALLFMHDVKVATKYVKKVTGKVAVRFKALGIAVVRKITEWFDLAVDTAASAAG 665
Query 646 WEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNL 705
W + ++ V ++T +E+ E V+ F F + DS+ + ++
Sbjct 666 WLCYQLVN--GLFAVANGVITFIQEVPELVKNFVDKFKTFFKVLIDSMSV------SILS 717
Query 706 GETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVL---TEEVVLKTGD 762
G T V + R C+ A ++ + ++LP ++ E G+
Sbjct 718 GLTVVKTASN--RVCL-------------AGSKVYEVVQKSLPAYIMPVGCSEATCLVGE 762
Query 763 LQP--LEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEK-YCALAPN----MMVTNNTFTL 815
++P E + V+APL C +I +K Y A + ++V N+T +
Sbjct 763 IEPAVFEDDVVDVVKAPLTYQGCCKPPSSFEKICIVDKLYMAKCGDQFYPVVVDNDTVGV 822
Query 816 KGG------APTKVTFGDD-TVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEV 868
A KV F D V EV + + I F LD D VL++ CS + V+ +
Sbjct 823 LDQCWRFPCAGKKVVFNDKPKVKEVPSTRKIKIIFALDATFDSVLSKACSEFEVDKDVTL 882
Query 869 NEFACVVADAVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFY 925
+E VV DAV TL P E + T + L+ YLFDE GE +AS MYCSF
Sbjct 883 DELLDVVLDAVESTLSPCKEHGVIGTKVCALLERLVDDYVYLFDEGGEEVIASRMYCSFS 942
Query 926 PPDED 930
PDED
Sbjct 943 APDED 947
Score = 59.7 bits (143), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 52/153 (34%), Positives = 82/153 (54%), Gaps = 2/153 (1%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV D+++ ++V V+VN AN + HG GVAGA+ KA A E+ D +
Sbjct 1319 ITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKAFINETADMVKA 1378
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNV--NKGEDIQLLKSAYENFNQHEVLLAPLLSA 1151
G +VGG +G L K L++VGP+ + E LL+ AY++ N+ + ++ L+SA
Sbjct 1379 QGVCQVGGCYESTGGKLCKKVLNIVGPDARGHGNECYSLLERAYQHINKCDNVVTTLISA 1438
Query 1152 GIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
GIF SL + V NV L +++ +D
Sbjct 1439 GIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFD 1471
Score = 40.0 bits (92), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 52/213 (24%), Positives = 84/213 (39%), Gaps = 25/213 (12%)
Query 1596 PTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLR-VEAFEYYHTTDPSFLGRYMSALNHTK 1654
P ++ D+ K++ E +T P D T V AF+ ++ S S H K
Sbjct 1047 PDQVEAFDIEKVEDSILSELQTELNAPADKTYEDVLAFDAIYSETLSAFYAVPSDETHFK 1106
Query 1655 KWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALI 1714
V G S NC+L + L+ +Q + L+F +Q + +AG F +
Sbjct 1107 ------VCGFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKL 1160
Query 1715 LAYCNKT-VGELGDVRETMSYLFQHANLDSC--KRVLNVVCKTCGQQQTTLKGVEAVMYM 1771
+ K+ + G +Y F L C K N C CG + L+G++AV +
Sbjct 1161 VKSAPKSIILPQGGYVADFAYFF----LSQCSFKVHANWRCLKCG-MELKLQGLDAVFFY 1215
Query 1772 GTLSYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
G + V C CG T L+ + P+
Sbjct 1216 GDV--------VSHMCKCGNSMT--LLSADIPY 1238
>sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus
133/2005 OX=389230 GN=1a PE=3 SV=1
Length=4441
Score = 1831 bits (4744), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 955/2183 (44%), Positives = 1372/2183 (63%), Gaps = 55/2183 (3%)
Query 2255 SNLGMPSYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDSLDTYPSLETIQITISS 2313
S LG+ + C G Y N T+ + +C+ S+ C CL G DSL Y +L+ +Q I+S
Sbjct 2274 SYLGIRTLCDGLAVEYRN-TSFDVVDFCSNRSVLCQWCLIGQDSLTRYSALQMLQTHITS 2332
Query 2314 FKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFA--VHFISNSWLMWLIINL 2371
+ ++ E+FLAY+L+T F VL L Q FF+Y + V++ + ++++ + L
Sbjct 2333 YVLNIDWIWFALEFFLAYVLYTSSFNVLLLVVTAQYFFAYTSAFVNWRAYNYIVSGLFFL 2392
Query 2372 VQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVR 2431
V P+ +VR+Y F A +++ K Y HV++GC + C++CYKRNR TRVE +TIV G +
Sbjct 2393 VTHIPLHGLVRVYNFLACLWFLRKFYSHVINGCKDTACLLCYKRNRLTRVEASTIVCGTK 2452
Query 2432 RSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIV 2491
R+FY+ ANGG +C HNWNCV CDT G+TFI EVA DL+ +R I PTDQS Y V
Sbjct 2453 RTFYIAANGGTSYCCKHNWNCVECDTAGVGNTFICTEVANDLTTTLRRLIKPTDQSHYYV 2512
Query 2492 DSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRAN---NTKGSLP-INVIVFDGKS 2547
DSV VK+ + L++++ G YER+ L +F NL+ L+ T +P N +++D
Sbjct 2513 DSVVVKDAVVELHYNRDGSSCYERYPLCYFTNLEKLKFKEVCKTPTGIPEHNFLIYDTND 2572
Query 2548 KCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPME 2607
+ +E+ A+SA VYYSQ++C+P+LL+D LV+ VGDS E+A+KM D+++N+F S F+V +
Sbjct 2573 RGQENLARSACVYYSQVLCKPMLLVDVNLVTTVGDSREIAIKMLDSFINSFISLFSVSRD 2632
Query 2608 KLKTLVATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDVETKDVVECLKLSHQSDIEVT 2666
KL+ L+ TA + + VL TF AAR V+SDVET VV+ L+ +H++DI++T
Sbjct 2633 KLEKLINTARDCVRRGDDFQTVLKTFTDAARGHAGVESDVETTMVVDALQYAHKNDIQLT 2692
Query 2667 GDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLR 2726
+ NNY+ Y K +++ DLG ID A +N ++ N A +WN D+M LS+ +
Sbjct 2693 TECYNNYVPGYIKPDSINTLDLGCLIDLKAASVNQTSMRNANGACVWNSGDYMKLSDSFK 2752
Query 2727 KQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVN---NWLKQLIKVTL----- 2778
+QIR A +K N+PF+LT + R N+++ K + KIV +WL ++ +T+
Sbjct 2753 RQIRIACRKCNIPFRLTTSKLRAADNILSVKFS--ATKIVGGAPSWLLRVRDLTVKGYCI 2810
Query 2779 --VFLF-VAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFD 2835
+F+F VA + + P + ++ I+ YK I+ G+ RDIA D CFANK+ F
Sbjct 2811 LTLFVFTVAVLSWFCLPSYSIATVNFNDDRILTYKVIENGIVRDIAPNDACFANKYGHFS 2870
Query 2836 TWFSQ-RGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGN 2894
WF++ GG Y N CP+ AVI G V +P T L + F+ RVF A N
Sbjct 2871 KWFNENHGGVYRNSVDCPITIAVIAGVAGARVANVPAT-LAWVGRQIVLFVSRVF-ANTN 2928
Query 2895 ICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRY 2954
+C+TP+ I Y F+ S CVL++ECT+F+DA G P+CYD VL G+ +Y ++P RY
Sbjct 2929 VCFTPTNEIPYDTFSDSGCVLSSECTLFRDAEGNLNPFCYDPTVLPGASSYADMKPHVRY 2988
Query 2955 VLMDGSI-IQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRS 3013
+ D + I+FP E ++R+ T ++YCR G+CE S AGVC+ST+G W L N Y +
Sbjct 2989 DMYDSDMYIKFPEVIFESTLRITKTLATQYCRFGSCEESAAGVCISTNGSWALYNQNYST 3048
Query 3014 LPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGE 3073
PG++CG D +++ + L QP+ +S S+ G ++ + +T YY + +RA +
Sbjct 3049 RPGIYCGDDYFDIVRRLAVSLFQPVTYFQLSTSLAMGLVLCVFLTAAFYYINKVKRALAD 3108
Query 3074 YSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFT 3133
Y+ + L++ LC L Y+ +Y Y TFYLT + +F+ HI W VMF
Sbjct 3109 YTQCAVVAVVAALLNSLCLCFIVANPLLVAPYTAMYYYATFYLTGEPAFIMHISWYVMFG 3168
Query 3134 PLVPFWITIAYIICISTKHFYWFFSNYLKRRV-VF-NGVSFSTFEEAALCTFLLNKEMYL 3191
+VP W+ +Y + + +H +W + + K+ V VF +G +F++AA F++ K+ Y+
Sbjct 3169 TVVPIWMLASYTVGVMLRHLFWVLAYFSKKHVDVFTDGKLNCSFQDAASNIFVIGKDTYV 3228
Query 3192 KLRSDVLLPLTQ--YNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVL 3249
LR+ +TQ + RYL+L+NKYKY+SGAMDT SYREA HL KAL +S +GSD+L
Sbjct 3229 ALRN----AITQDSFVRYLSLFNKYKYYSGAMDTASYREACAAHLCKALQTYSETGSDIL 3284
Query 3250 YQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTS 3309
YQPP S+TS+VLQSG KM+ PSG VE C+VQVTCG+ TLNGLWLD+ V+CPRH++C +
Sbjct 3285 YQPPNCSVTSSVLQSGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPA 3344
Query 3310 EDMLNPNYEDLLIRKSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKF 3366
+ + +PNY+ LLI K+NH+F+VQ LRV+ HSM +LKL VD ANP TP Y F
Sbjct 3345 DQLTDPNYDALLISKTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTF 3404
Query 3367 VRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMH 3426
++PG +FSVLACYNG P+GV+ +R N TIKGSFL GSCGSVG+ + ++F YMH
Sbjct 3405 STVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVLNFVYMH 3464
Query 3427 HMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRF 3486
MEL G H G+ +G YG F D+QT Q TD T+NV+AWLYAAV+NG +WF+
Sbjct 3465 QMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPT 3524
Query 3487 TTTLNDFNLVAMKYNY-EPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTIL 3545
+ +N A+ + E + +D+L + +TG++V M A+++ L G G+TIL
Sbjct 3525 RVGIVTYNEWALSNQFTEFVGTQSIDML---AHRTGVSVEQMLAAIQSL-HAGFQGKTIL 3580
Query 3546 GSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFF 3605
G + LEDEFTP DV Q GV QS VKR G HWL+ T++ + + ++Q T+++++ +
Sbjct 3581 GQSTLEDEFTPDDVNMQVMGVVMQSGVKRISYGFMHWLMSTLVLAYVSVMQLTKFTMWTY 3640
Query 3606 LYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVM 3661
L+E + A M VKHKH FL LFLLP + Y N+VY P +S ++
Sbjct 3641 LFETIPTQMTPLLFGFMACVMFTVKHKHTFLSLFLLPVALCLTYANIVYEPQTLVSSTLI 3700
Query 3662 RIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKV 3721
+ WL + L D +Y S +L ++ R + L + + Y
Sbjct 3701 AVANWLTPTSVYMRTTHL-DFGLYISLSFVLAIIVRRLYRPSMSNLALALCSGVMWFYTY 3759
Query 3722 YYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIML 3781
G+ I+ I ++TS+Y+ V + LA+ I + Y P ++ ++L
Sbjct 3760 VIGDH-SSPITYLMFITTLTSDYTITVFATVNLAKFISGLVFLYAPHLGFILPEVKLVLL 3818
Query 3782 VYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLN 3841
+Y LGY CT YFG+F LLN R+ LGVYDY VSTQEFR++ GL P+NS +A LN
Sbjct 3819 IYLCLGYMCTMYFGVFSLLNLKLRVPLGVYDYSVSTQEFRFLTGNGLHAPRNSWEALILN 3878
Query 3842 IKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLA 3901
KLLG+GG PCIKVATVQSK++D+KCTSVVLL+VLQQL +ES+SK W+ CV+LHN+IL A
Sbjct 3879 FKLLGIGGTPCIKVATVQSKLTDLKCTSVVLLTVLQQLHLESNSKAWSYCVKLHNEILAA 3938
Query 3902 KDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQ 3961
D TEAFE+ V L + L+S VD++ L ++ +N + LQA +EFS L +YA TAQ
Sbjct 3939 VDPTEAFERFVCLFATLMSFSANVDLDALANDLFENSSVLQATLTEFSHLATYAELETAQ 3998
Query 3962 EAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
+Y++A+ +GD S VLK L+K++NVAK+ +++D A+ RKLE+MA+QAMT MYKQAR+ED
Sbjct 3999 SSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKLERMAEQAMTSMYKQARAED 4058
Query 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
K+AK+ SAMQTMLF M++KLDND LN +I NAR+GCVPL+I+PL + KL VVIPD + +
Sbjct 4059 KKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSIVPLCASNKLRVVIPDISVW 4118
Query 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA-NSAVKL 4139
+ + +YA +LW++ + + D+++V+ +++ ++ + +L WPL++ RA +SAVKL
Sbjct 4119 NKVVNWPSVSYAGSLWDVTVINNVDNEVVKPTDV-VETNESLTWPLVIECSRASSSAVKL 4177
Query 4140 QNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKS 4199
QNNE+ P L+ M AG Q C+ +A+AYY +G R V+ LLS+ LKWA+
Sbjct 4178 QNNEIHPKGLKTMVVTAGIDQVNCS-SSAVAYYEPVQGHRMVMGLLSENAHLKWAKVEGK 4236
Query 4200 DGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATE 4259
D G I EL+PPC+F+ PKGP+++YLYF+K LNNL+RG +LG +AATVRLQAG TE
Sbjct 4237 D--GFINIELQPPCKFLIAGPKGPEIRYLYFVKNLNNLHRGQLLGHIAATVRLQAGANTE 4294
Query 4260 VPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQE 4319
+NSTVL+ AFAVD AKAY DY+ SGG P++N VKML TGTG AI+V PEA DQE
Sbjct 4295 FASNSTVLTLVAFAVDPAKAYLDYVGSGGTPLSNYVKMLAPKTGTGVAISVKPEATADQE 4354
Query 4320 SFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGY 4379
++GGAS CLYCR HI+HP+ G C K ++VQIP DPVGF LKN C VC W GY
Sbjct 4355 TYGGASVCLYCRAHIEHPDVSGVCKYKTRFVQIPAH-VRDPVGFLLKNVPCNVCQYWVGY 4413
Query 4380 GCSCDQLREPMLQSADAQSFLNR 4402
GC+CD LR + + +FLN
Sbjct 4414 GCNCDALRNNTVPQSKDTNFLNE 4436
Score = 303 bits (776), Expect = 4e-80, Method: Compositional matrix adjust.
Identities = 225/771 (29%), Positives = 367/771 (48%), Gaps = 46/771 (6%)
Query 1391 VCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPL 1450
+C E A V ++ K + VD G +Y Y+++ + +I N + MP
Sbjct 1352 ICTEYSANVKFLRTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGC-PGICAMPF 1409
Query 1451 GYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGS 1510
GYVTHGL+L ++ Y+R +KVP ++S + + N + + +TPE FI ++ G
Sbjct 1410 GYVTHGLDLAQSGNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGG 1467
Query 1511 YKDWSY-SGQSTQLGI---EFLKRGDKSVYYTSNPTTFHLDGEVITFDNL---KTLLSLR 1563
Y W SG + + L +++ Y N + + F +L + L+ R
Sbjct 1468 YHSWHLVSGDLIVKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFSDLEACRAYLTSR 1527
Query 1564 EVR--TIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVL 1621
+ I+V T+D +N T +++ + T+ +Q G T+ G D++ P G++ +V
Sbjct 1528 AAQQVNIEVLVTIDGVNFRTVILNDATTFRKQLGATFYKGVDISDALPTVKMGGESLFVA 1587
Query 1622 PN-DDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
N ++ V EYY T+D +FL RY S ++WK+ +G+ S+K ++ NCY+ +
Sbjct 1588 DNLSESEEVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATI 1647
Query 1681 LTLQQI-ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHA 1739
+ + + ++KF PALQ+AY R + G+ +F ALI+AY + T D + + L A
Sbjct 1648 MMIDMLHDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKA 1707
Query 1740 NLD-SCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLV 1798
L S K V C CG + G+ A +Y G S E+ + C CG + LV
Sbjct 1708 ELTVSAKMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLV 1767
Query 1799 QQESPFVMMSAPPAQYELKHGTFTCASEYTGNY------QCGHYKHITSKETL-YCIDGA 1851
+ +P++++S E+K T T N GHY H+ K+ L Y D
Sbjct 1768 EHSTPWLLVSG---LNEVKVSTSTDPVYRAFNVFQGVETSVGHYVHVRVKDGLFYKYDSG 1824
Query 1852 LLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQP 1911
LTK+S+ K +T V+Y + YT V Y LDGV E++P L NYY KD Y+T +P
Sbjct 1825 SLTKTSDMKCKMTSVWYPKVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKP 1884
Query 1912 -IDLVPNQPYPNASFDNFKFV-CDNIKFADDL----NQLTGYK--KPASRELKVTFFPDL 1963
I P P + + N V D +D + N L G+ KP S++L + P+
Sbjct 1885 TIKYSPATILPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNE 1944
Query 1964 NGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSN 2023
+GDV+ ++ +Y P +KKG L KPI+W N + A KPN +R L+ P+ N
Sbjct 1945 DGDVLLSEFNNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDN 2004
Query 2024 SFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTE---VVGDIILKPA 2080
+ VL+ +Q + E PV E+V + ++E K V G+
Sbjct 2005 KYTVLQDNTSQLI-----EPNVPVVEDV---SITTRKLIEVKCKGLNKPFVKGNFSFVND 2056
Query 2081 NNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLATHGLAAV 2130
N + + + +G T+L A YVD N+ + + N S + L T+ + L V
Sbjct 2057 PNGVTVVDTLGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVESGDLQIV 2107
Score = 170 bits (431), Expect = 5e-40, Method: Compositional matrix adjust.
Identities = 229/978 (23%), Positives = 411/978 (42%), Gaps = 100/978 (10%)
Query 8 FNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEVLSEARQHLKD-GTCGLVEVE-KGV 60
+NEK HV ++P+ D+ L F D E ++ LK+ G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTEDMASKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETL-----GVLVPHVGEIP 115
+ L P V++ H +V +A + + TL G+ P+ +
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDHVGAAMMRTTLNVKPLGMFFPYDSSLE 139
Query 116 VAYRKVLLRKNGNKGAGGHSYGADLKS---FDLGDELGTDPYEDFQENWNTKHSSGVTRE 172
LLRKNG G D K ++ D+L DP + +N
Sbjct 140 TGEHTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSE-QLDF---IDTKRGV 228
L+++L GG VD CG +G P+ ++A+ G TL++ ++D +D+ R +
Sbjct 188 LLKKLIGGDCIP-VDQYMCGKNGKPIADYAKIVAKEGLT--TLADIEVDVKSRMDSDRFI 244
Query 229 YCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQP-- 286
+ + + W R Y QT F + + D P F + S I + P
Sbjct 245 -VLNKKLYRVVWNVTRRNVPYSKQTAFTVVSVIQCDD-KESVPEHTFTIGSQILMVSPLK 302
Query 287 RVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGT 346
K + + + Y + + + S + C+ CG +W TG+ ++ CG
Sbjct 303 ATNNKNFNLKQRLLHTFYGKEAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGA 362
Query 347 ENLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGR--T 403
+ + G +P+NA+ CP +N H+ A+ ++ K + GG+ T
Sbjct 363 NYSANDVDLQSSGLVPKNALFLANCPCANNGAC--SHNAAQVYSILDGKACVEVGGKSFT 420
Query 404 IAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEKV 459
+ FGG V++Y+GC + Y+VPRA + + + G G D ++E L+K +
Sbjct 421 LTFGGVVYAYMGCCDGTMYFVPRAKSCVS-RIGDAIFTGCTGTWDKVVETANLFLEKAQH 479
Query 460 NINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN--FKVTKGKAK 517
++N F L E ++LA S +TS F E +++++ + N F VT G
Sbjct 480 SLNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDYI 536
Query 518 KGAWNIGE----QKSILSPLYAFA--SEAARVVRSI---FSRTLETAQN---SVRVLQKA 565
+ A NIG +I +P AF E+ + V +I L++A + S + +
Sbjct 537 RDAINIGANGVCNATINAPFIAFTGLGESFKKVAAIPWKICSNLKSALDYYCSNIMFRVF 596
Query 566 AITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYE--- 622
I ++ + L+D T V +Y V++ + + GTV
Sbjct 597 PYDIPCDVNDFVELLLDCGKLT--------VATSYF---VLRYLDEKFDTVLGTVSNACQ 645
Query 623 -KLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKL 681
L L+ + F+ D +++ K + V A+ + VQ +
Sbjct 646 TALSSFLNACVAASRATAGFISDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLDI 705
Query 682 VNKFLALCADSIIIGGAKLKALNL-GETFVTHSKGLYRKCVKSREET-----GLLMPLKA 735
++K + L ++ G KL A+ G + + G Y C+ ++ +T L++P
Sbjct 706 MSKAMKLLHTNVSWAGTKLSAIIYEGREALLFNSGTYF-CLSTKAKTLQDQMNLVLPGDY 764
Query 736 PKEIIFL-----EGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLML 790
K+ + + +T+ + V + G L +PT+E + +VG V ++ +
Sbjct 765 NKKTLGILDPVPNADTIDVTANSTVVDVVHGQL----EPTNEHGPSMIVGNYVLVSDKLF 820
Query 791 LEIKDTEKYCALAPNMMVTNNTFTLKGGAPT-KVTFGDDTVIEVQGYKSVNITFELDERI 849
+ D E Y L N V + F LKGG P+ KVTFGD +EV Y+SV+IT+++ +
Sbjct 821 VRTDDEEFY-PLCINGKVVSTLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPVL 879
Query 850 DKVL-NEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLF 908
D +L + K + +TVE V +F V+ D V+ L P+ G D++++ Y++
Sbjct 880 DALLSSSKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYVY 939
Query 909 DESGEFKLASHMYCSFYP 926
++ G+ +S+M S P
Sbjct 940 NQDGDCAWSSNMTFSINP 957
Score = 128 bits (322), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 71/176 (40%), Positives = 107/176 (61%), Gaps = 8/176 (5%)
Query 991 QDGSEDNQT-------TTIQTIVE-VQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKN 1042
QD + +NQ T +T VE VQP+ ++ + ++ S + + ++V +
Sbjct 1117 QDEASENQVHQVPDLQCTSETKVEIVQPRQDLRPRRLRKSKVDLSKYKHTVINNSVTLVL 1176
Query 1043 ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGS 1102
D ++ A + V+VNAAN +LKHGGG+AGA+NKA+ +Q ESD+YI+ +GPL VG S
Sbjct 1177 GDAIQIASLLPKCVLVNAANRHLKHGGGIAGAINKASGGDVQEESDEYISNSGPLHVGDS 1236
Query 1103 CVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADP 1158
+L G+ LA L VVGP+ ED LLK Y+ FN+H +++ PL+S+GIF DP
Sbjct 1237 VLLKGYGLADAILRVVGPDARNNEDAALLKRCYKTFNKHTIVVTPLISSGIFSVDP 1292
>sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus
HKU4 OX=694007 GN=1a PE=1 SV=1
Length=4434
Score = 1828 bits (4736), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 960/2214 (43%), Positives = 1382/2214 (62%), Gaps = 61/2214 (3%)
Query 2230 IIWFLLLSVCLGSLIYSTAALGVLM------SNLGMPSYCTGYREGYLNSTNVTIATYCT 2283
I +L + L S + A G+L S LG+ + C G Y N T+ + +C+
Sbjct 2236 IYHLVLFNQVLSSDVMLEDATGILAIYKEVRSYLGIRTLCDGLVVEYRN-TSFDVMEFCS 2294
Query 2284 G-SIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLG 2342
S+ C CL G DSL Y +L+ +Q I+S+ ++ E+FLAY+L+T F VL
Sbjct 2295 NRSVLCQWCLIGQDSLTRYSALQMLQTHITSYVLNIDWIWFALEFFLAYVLYTSSFNVLL 2354
Query 2343 LAAIMQLFFSYFA--VHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
L Q FF+Y + V++ + ++++ + LV P+ +VR+Y F A +++ K Y HV
Sbjct 2355 LVVTAQYFFAYTSAFVNWRAYNYIVSGLFFLVTHIPLHGLVRVYNFLACLWFLRKFYSHV 2414
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
++GC + C++CYKRNR TRVE +TIV G +R+FY+ ANGG +C HNWNCV CDT
Sbjct 2415 INGCKDTACLLCYKRNRLTRVEASTIVCGTKRTFYIAANGGTSYCCKHNWNCVECDTAGV 2474
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G+TFI EVA DL+ +R I PTDQS Y VDSV VK+ + L++++ G YER+ L +
Sbjct 2475 GNTFICTEVANDLTTTLRRLIKPTDQSHYYVDSVVVKDAVVELHYNRDGSSCYERYPLCY 2534
Query 2521 FVNLDNLRAN---NTKGSLP-INVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQAL 2576
F NL+ L+ T +P N +++D + +E+ A+SA VYYSQ++C+P+LL+D L
Sbjct 2535 FTNLEKLKFKEVCKTPTGIPEHNFLIYDTNDRGQENLARSACVYYSQVLCKPMLLVDVNL 2594
Query 2577 VSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISA 2636
V+ VGDS E+A+KM D+++N+F S F+V +KL+ L+ TA + + NVL TF A
Sbjct 2595 VTTVGDSREIAIKMLDSFINSFISLFSVSRDKLEKLINTARDCVRRGDDFQNVLKTFTDA 2654
Query 2637 AR-QGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCS 2695
AR V+SDVET VV+ L+ +H++DI++T + NNY+ Y K +++ DLG ID
Sbjct 2655 ARGHAGVESDVETTMVVDALQYAHKNDIQLTTECYNNYVPGYIKPDSINTLDLGCLIDLK 2714
Query 2696 ARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVT 2755
A +N ++ N A +WN D+M LS+ ++QIR A +K N+PF+LT + R N+++
Sbjct 2715 AASVNQTSMRNANGACVWNSGDYMKLSDSFKRQIRIACRKCNIPFRLTTSKLRAADNILS 2774
Query 2756 TKIALKGGKIVN---NWLKQLIKVTL-------VFLF-VAAIFYLITPVHVMSKHTDFSS 2804
K + KIV +WL ++ +T+ +F+F VA + + P + ++
Sbjct 2775 VKFS--ATKIVGGAPSWLLRVRDLTVKGYCILTLFVFTVAVLSWFCLPSYSIATVNFNDD 2832
Query 2805 EIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQ-RGGSYTNDKACPLIAAVITREVG 2863
I+ YK I+ G+ RDIA D CFANK+ F WF++ GG Y N CP+ AVI G
Sbjct 2833 RILTYKVIENGIVRDIAPNDVCFANKYGHFSKWFNENHGGVYRNSMDCPITIAVIAGVAG 2892
Query 2864 FVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFK 2923
V +P L + F+ RVF A N+C+TP I Y F+ S CVL++ECT+F+
Sbjct 2893 ARVANVPAN-LAWVGKQIVLFVSRVF-ANTNVCFTPINEIPYDTFSDSGCVLSSECTLFR 2950
Query 2924 DASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSI-IQFPNTYLEGSVRVVTTFDSE 2982
DA G P+CYD VL G+ +Y ++P RY + D + I+FP +E ++R+ T ++
Sbjct 2951 DAEGNLNPFCYDPTVLPGASSYADMKPHVRYDMYDSDMYIKFPEVIVESTLRITKTLATQ 3010
Query 2983 YCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALD 3042
YCR G+CE S AGVC+ST+G W L N Y + PG++CG D +++ + L QP+
Sbjct 3011 YCRFGSCEESAAGVCISTNGSWALYNQNYSTRPGIYCGDDYFDIVRRLAISLFQPVTYFQ 3070
Query 3043 ISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLP 3102
+S S+ G ++ + +T YY + +RA +Y+ + L++ LC L
Sbjct 3071 LSTSLAMGLVLCVFLTAAFYYINKVKRALADYTQCAVVAVVAALLNSLCLCFIVANPLLV 3130
Query 3103 GVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLK 3162
Y+ +Y Y TFYLT + +F+ HI W VMF +VP W+ +Y + + +H +W + + K
Sbjct 3131 APYTAMYYYATFYLTGEPAFIMHISWYVMFGAVVPIWMLASYTVGVMLRHLFWVLAYFSK 3190
Query 3163 RRV-VF-NGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQ--YNRYLALYNKYKYFS 3218
+ V VF +G +F++AA F++ K+ Y+ LR+ +TQ + RYL+L+NKYKY+S
Sbjct 3191 KHVDVFTDGKLNCSFQDAASNIFVIGKDTYVALRN----AITQDSFVRYLSLFNKYKYYS 3246
Query 3219 GAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEG 3278
GAMDT SYREA HL KAL +S +GSD+LYQPP S+TS+VLQSG KM+ PSG VE
Sbjct 3247 GAMDTASYREACAAHLCKALQTYSETGSDILYQPPNCSVTSSVLQSGLVKMSAPSGAVEN 3306
Query 3279 CMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQ---AGN 3335
C+VQVTCG+ TLNGLWLD+ V+CPRH++C ++ + +PNY+ LLI K+NH+F+VQ
Sbjct 3307 CIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLISKTNHSFIVQKHIGAQ 3366
Query 3336 VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRP 3395
LRV+ HSM +LKL VD ANP TP Y F ++PG +FSVLACYNG P+GV+ +R
Sbjct 3367 ANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRH 3426
Query 3396 NFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQ 3455
N TIKGSFL GSCGSVG+ + ++F YMH MEL G H G+ +G YG F D+QT Q
Sbjct 3427 NSTIKGSFLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQ 3486
Query 3456 AAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY-EPLTQDHVDILG 3514
TD T+NV+AWLYAAV+NG +WF+ + +N A+ + E + +D+L
Sbjct 3487 LQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVGTQSIDML- 3545
Query 3515 PLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKR 3574
+ +TG++V M A+++ L G G+TILG + LEDEFTP DV Q GV QS VKR
Sbjct 3546 --AHRTGVSVEQMLAAIQSL-HAGFQGKTILGQSTLEDEFTPDDVNMQVMGVVMQSGVKR 3602
Query 3575 TIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHA 3634
G HWL+ T + + + ++Q T+++++ +L+E ++ A M VKHKH
Sbjct 3603 ISYGFIHWLISTFVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLLGFMACVMFTVKHKHT 3662
Query 3635 FLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVV 3690
F+ LFLLP + Y N+VY P +S ++ + WL + D +Y S
Sbjct 3663 FMSLFLLPVALCLTYANIVYEPQTLISSTLIAVANWLTPTSVYMRTTHF-DFGLYISLSF 3721
Query 3691 LLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTT 3750
+L ++ R + L + + Y G+ I+ I ++TS+Y+ V
Sbjct 3722 VLAIIVRRLYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYTITVFA 3780
Query 3751 VMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGV 3810
+ LA+ I + Y P ++ ++L+Y LGY CT YFG+F LLN R+ LGV
Sbjct 3781 TVNLAKFISGLVFFYAPHLGFILPEVKLVLLIYLGLGYMCTMYFGVFSLLNLKLRVPLGV 3840
Query 3811 YDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSV 3870
YDY VSTQEFR++ GL P+NS +A LN KLLG+GG PCIKVATVQSK++D+KCTSV
Sbjct 3841 YDYSVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQSKLTDLKCTSV 3900
Query 3871 VLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKL 3930
VLL+VLQQL +ES+SK W+ CV+LHN+IL A D TEAFE+ V L + L+S VD++ L
Sbjct 3901 VLLTVLQQLHLESNSKAWSYCVKLHNEILAAVDPTEAFERFVCLFATLMSFSANVDLDAL 3960
Query 3931 CEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKS 3989
++ +N + LQA +EFS L +YA TAQ +Y++A+ +GD S VLK L+K++NVAK+
Sbjct 3961 ANDLFENSSVLQATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKN 4020
Query 3990 EFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNII 4049
+++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I
Sbjct 4021 AYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVI 4080
Query 4050 NNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIV 4109
NAR+GCVPL+I+PL + KL VVIPD + + + + +YA +LW+I + + D+++V
Sbjct 4081 ANARNGCVPLSIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVV 4140
Query 4110 QLSEISMDNSPNLAWPLIVTALR-ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNA 4168
+ +++ ++ + +L WPL++ R ++SAVKLQNNE+ P L+ M AG Q C + +A
Sbjct 4141 KPTDV-VETNESLTWPLVIECSRSSSSAVKLQNNEIHPKGLKTMVITAGVDQVNC-NSSA 4198
Query 4169 LAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL 4228
+AYY +G R V+ LLS+ LKWA+ D G I EL+PPC+F+ PKGP+++YL
Sbjct 4199 VAYYEPVQGHRMVMGLLSENAHLKWAKVEGKD--GFINIELQPPCKFLIAGPKGPEIRYL 4256
Query 4229 YFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGG 4288
YF+K LNNL+RG +LG +AATVRLQAG TE +NSTVL+ AFAVD AKAY DY+ SGG
Sbjct 4257 YFVKNLNNLHRGQLLGHIAATVRLQAGANTEFASNSTVLTLVAFAVDPAKAYLDYVGSGG 4316
Query 4289 QPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGK 4348
P++N VKML TGTG AI+V PEA DQE++GGAS CLYCR HI+HP+ G C K +
Sbjct 4317 TPLSNYVKMLAPKTGTGVAISVKPEATADQETYGGASVCLYCRAHIEHPDVSGVCKYKTR 4376
Query 4349 YVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNR 4402
+VQIP DPVGF LKN C VC W GYGC+CD LR + + +FLN
Sbjct 4377 FVQIPAH-VRDPVGFLLKNVPCNVCQYWVGYGCNCDALRNNTVPQSKDTNFLNE 4429
Score = 306 bits (784), Expect = 4e-81, Method: Compositional matrix adjust.
Identities = 226/771 (29%), Positives = 368/771 (48%), Gaps = 46/771 (6%)
Query 1391 VCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPL 1450
+C E A V ++ K + VD G +Y Y+++ + +I N + + MP
Sbjct 1345 ICTEYSANVKFLRTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGCS-GICAMPF 1402
Query 1451 GYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGS 1510
GYVTHGL+L ++ Y+R +KVP ++S + + N + + +TPE FI ++ G
Sbjct 1403 GYVTHGLDLAQSGNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGG 1460
Query 1511 YKDWSY-SGQSTQLGI---EFLKRGDKSVYYTSNPTTFHLDGEVITFDNL---KTLLSLR 1563
Y W SG + + L +++ Y N + + F +L + L+ R
Sbjct 1461 YHSWHLVSGDLIVKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFSDLEACRAYLTSR 1520
Query 1564 EVR--TIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVL 1621
+ I+V T+D +N T +++ + T+ +Q G T+ G D++ P G++ +V
Sbjct 1521 AAQQVNIEVLVTIDGVNFRTVILNDTTTFRKQLGATFYKGVDISDAFPTVKMGGESLFVA 1580
Query 1622 PN-DDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
N ++ +V EYY T+D +FL RY S ++WK+ +G+ S+K ++ NCY+ +
Sbjct 1581 DNLSESEKVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATI 1640
Query 1681 LTLQQI-ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHA 1739
+ + + ++KF PALQ+AY R + G+ +F ALI+AY + T D + + L A
Sbjct 1641 MMIDMLHDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKA 1700
Query 1740 NLD-SCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLV 1798
L S K V C CG + G+ A +Y G S E+ + C CG + LV
Sbjct 1701 ELTVSAKMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLV 1760
Query 1799 QQESPFVMMSAPPAQYELKHGTFTCASEYTGNY------QCGHYKHITSKETL-YCIDGA 1851
+ +P++++S E+K T T N GHY HI K+ L Y D
Sbjct 1761 EHSAPWLLVSG---LNEVKVSTSTDPIYRAFNVFQGVETSVGHYVHIRVKDGLFYKYDSG 1817
Query 1852 LLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQP 1911
LTK+S+ K +T V+Y YT V Y LDGV E++P L NYY KD Y+T +P
Sbjct 1818 SLTKTSDMKCKMTSVWYPTVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKP 1877
Query 1912 -IDLVPNQPYPNASFDNFKFV-CDNIKFADDL----NQLTGYK--KPASRELKVTFFPDL 1963
I P P + + N V D +D + N L G+ KP S++L + P+
Sbjct 1878 TIKYSPATILPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNE 1937
Query 1964 NGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSN 2023
+GDV+ ++ +Y P +KKG L KPI+W N + A KPN +R L+ P+ N
Sbjct 1938 DGDVLLSEFSNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDN 1997
Query 2024 SFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTE---VVGDIILKPA 2080
+ VL+ +Q E PV ++V P + ++E K V G+
Sbjct 1998 KYTVLQDNTSQ-----LVEHNVPVVDDV---PITTRKLIEVKCKGLNKPFVKGNFSFVND 2049
Query 2081 NNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLATHGLAAV 2130
N + + + +G T+L A YVD N+ + + N S + L T+ + L V
Sbjct 2050 PNGVTVVDTLGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVESGDLQIV 2100
Score = 249 bits (636), Expect = 7e-64, Method: Compositional matrix adjust.
Identities = 316/1307 (24%), Positives = 534/1307 (41%), Gaps = 198/1307 (15%)
Query 8 FNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEVLSEARQHLKD-GTCGLVEVE-KGV 60
+NEK HV ++P+ D+ L F D E ++ LK+ G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTDDMACKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGR-----SGETLGVLVPHVGEIP 115
+ L P V++ H +V +A + + + + LG+ P+ +
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDQVGAAMMRTTLNAKPLGMFFPYDSSLE 139
Query 116 VAYRKVLLRKNGNKGAGGHSYGADLKS---FDLGDELGTDPYEDFQENWNTKHSSGVTRE 172
LLRKNG G D K ++ D+L DP + +N
Sbjct 140 TGEYTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSE-QLDF---IDTKRGV 228
L+++L GG +D CG +G P+ ++A+ G TL++ ++D +D+ R +
Sbjct 188 LLKKLIGGDCIP-IDQYMCGKNGKPIADYAKIVAKEGLT--TLADIEVDVKSRMDSDRFI 244
Query 229 YCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRV 288
+ + + W R Y QT F I + D P F + S I + P +
Sbjct 245 -VLNKKLYRVVWNVTRRNVPYPKQTAFTIVSVVQCDD-KDSVPEHTFTIGSQILMVSP-L 301
Query 289 EKKKLDGFMGRIRSVYPVASPNECNQ---MCLSTLMKCDHCGETSWQTGDFVKATCEFCG 345
+ F + R +Y + Q + S + C+ CG +W TG+ ++ CG
Sbjct 302 KATNNKNFNLKQRLLYTFYGKDAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCG 361
Query 346 TENLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGR-- 402
+ + G +P+NA+ CP +N HS A+ +N K + GG+
Sbjct 362 ANYSANDVDLQSSGLVPRNALFLANCPCANNGAC--SHSAAQVYNILDGKACVEVGGKSF 419
Query 403 TIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEK 458
T+ FGG V++Y+GC + Y+VPRA + + + G G D ++E L+K +
Sbjct 420 TLTFGGVVYAYMGCCDGTMYFVPRAKSCVS-RIGDAIFTGCTGTWDKVVETANLFLEKAQ 478
Query 459 VNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN--FKVTKGKA 516
++N F L E ++LA S +TS F E +++++ + N F VT G
Sbjct 479 RSLNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDY 535
Query 517 KKGAWNIGEQ----KSILSPLYAFAS--EAARVVRSI---FSRTLETAQN---SVRVLQK 564
+ A NIG +I +P AF E+ + V +I L++A + S + +
Sbjct 536 IRDAINIGANGVCNATINAPFIAFTGLGESFKKVSAIPWKICSNLKSALDYYSSNIMFRV 595
Query 565 AAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEK- 623
I +S + L+D T V +Y V++ + + GTV
Sbjct 596 FPYDIPCDVSNFVELLLDCGKLT--------VATSYF---VLRYLDEKFDTVLGTVSSAC 644
Query 624 ---LKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFK 680
L L+ + F+ D +++ K + V A+ + VQ
Sbjct 645 QTALSSFLNACVAASRATAGFINDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLD 704
Query 681 LVNKFLALCADSIIIGGAKLKALNL-GETFVTHSKGLYRKCVKSREET-----GLLMPLK 734
+++K + L ++ G KL A+ G + + G Y C+ ++ +T L++P
Sbjct 705 IMSKAMKLLHTNVSWAGTKLSAIIYEGREALLFNSGTYF-CLSTKAKTLQGQMNLVLPGD 763
Query 735 APKEIIFL-----EGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLM 789
K+ + + +T+ + V + G L+P T+E + +VG V ++ +
Sbjct 764 YNKKTLGILDPVPNADTIDVNANSTVVDVVHGQLEP----TNEHGPSMIVGNYVLVSDKL 819
Query 790 LLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSVNITFELDER 848
+ +D E Y L N V + F LKGG P+K VTFGD +EV Y+SV+IT+++
Sbjct 820 FVRTEDEEFY-PLCTNGKVVSTLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPV 878
Query 849 IDKVL-NEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYL 907
+D +L + K + +TVE V +F V+ D V+ L P+ G D++++ Y+
Sbjct 879 LDALLSSSKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYV 938
Query 908 FDESGEFKLASHMYCSFYP--------------------PDEDEEEGDCEE-EEFEPSTQ 946
+++ G+ +S+M S P P D+EE EE P
Sbjct 939 YNQDGDCAWSSNMTFSINPVEDVEEVEEFIEDDYLSDELPIADDEEAWARAVEEVMPLDD 998
Query 947 YEYGTEDDYQGKPLEFGATSA---ALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQ 1003
+ + PLE S ++ E QE DS + G D +
Sbjct 999 ILVAEIELEEDPPLETALESVEAEVVETAEAQEPSVESIDSTPSTSTVVGENDLSVKPMS 1058
Query 1004 TIVEVQPQLEME----------LTPVV----------QTIEVNSFSGYLKLTDNVYIKNA 1043
+ E LE+E +T +V Q V+S + ++N + +
Sbjct 1059 RVAETDDVLELETAVVGGPVSDVTAIVTNDIVSVEQAQQCGVSSLPIQDEASENQVHQVS 1118
Query 1044 D--------------IVEEAKKVKP---------------TVVVNAANVYLKHGGGVAGA 1074
D IV+ + +KP TV+ N+ + L +A
Sbjct 1119 DLQGNELLCSETKVEIVQPRQDLKPRRSRKSKVDLSKYKHTVINNSVTLVLGDAIQIASL 1178
Query 1075 LNK-----------------------ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA 1111
L K A+ +Q ESD+YI+ NGPL VG S +L GH LA
Sbjct 1179 LPKCILVNAANRHLKHGGGIAGVINKASGGDVQEESDEYISNNGPLHVGDSVLLKGHGLA 1238
Query 1112 KHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADP 1158
LHVVGP+ ED LLK Y+ FN+H +++ PL+SAGIF DP
Sbjct 1239 DAILHVVGPDARNNEDAALLKRCYKAFNKHTIVVTPLISAGIFSVDP 1285
>sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronavirus
(strain A59) OX=11142 GN=1a PE=1 SV=1
Length=4468
Score = 1828 bits (4734), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1080/2906 (37%), Positives = 1599/2906 (55%), Gaps = 160/2906 (6%)
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTL 1627
+ V TVD +N + V +G+ G + DG +VTK++ ++GK F+ +
Sbjct 1611 VDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIYKGKVFFQYSDLSEA 1670
Query 1628 RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIE 1687
+ A + D L +Y + L K W + K ++NNCY+ A L LQ +
Sbjct 1671 DLVAVKDAFGFDEPQLLKYYTMLGMCK-WPVVVCGNYFAFKQSNNNCYINVACLMLQHLS 1729
Query 1688 LKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRV 1747
LKF Q+A+ R+G+ F +L+LA + E D + M + + A+L
Sbjct 1730 LKFPKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDSIDFMRVVLREADLSGATCN 1789
Query 1748 LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
L VCK CG +Q KGV+AVM+ GTL +G I CTCG + + Q PF++
Sbjct 1790 LEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLVRGYNIACTCGSKLV-HCTQFNVPFLIC 1847
Query 1808 SAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVF 1867
S P +L A+ +TG GHY H+ K D + K SE KG TD
Sbjct 1848 SNTPEGRKLPDDVVA-ANIFTGG-SVGHYTHVKCKPKYQLYDACNVNKVSEAKGNFTDCL 1905
Query 1868 YKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--NAS 1924
Y +N T + T+ LD V C E P L YY + Y+T +PI + + +
Sbjct 1906 YLKNLKQTFSSVLTTFYLDDVKCVEYKPDLSQYYCESGKYYT-KPIIKAQFRTFEKVDGV 1964
Query 1925 FDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGA 1983
+ NFK V +I A+ LN G+ E K+T +P GDVV Y + G
Sbjct 1965 YTNFKLVGHSI--AEKLNAKLGFDCNSPFVEYKITEWPTATGDVVLASDDLYVSRYSSGC 2022
Query 1984 KLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVETSNSFDV-----------L 2028
KP+VW H + TY +P+ C ++ PV+ S D +
Sbjct 2023 ITFGKPVVWLGHEEASLKSLTYFNRPSVVC-ENKFNVLPVDVSEPTDKGPVPAAVLVTGV 2081
Query 2029 KSEDAQGMDNLACEDLKPVSE--------EVVENPTIQ-KDVLECNV----KTTEVVGDI 2075
DA +A E S EV + P++ DV E + K +V G +
Sbjct 2082 PGADASAGAGIAKEQKACASASVEDQVVTEVRQEPSVSAADVKEVKLNGVKKPVKVEGSV 2141
Query 2076 ILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPW 2135
++ + K+ + + D+ ++ + NELSR+ VNS
Sbjct 2142 VVNDPTSETKVVKSLSIVDVYDMFLTGCKYVVWTANELSRL-------------VNS--- 2185
Query 2136 DTIANYAKPFLNKVVSTTTNIVTRCLNR-------------VCTNYMPYFFTLLLQLCTF 2182
T+ Y K + K+V+ ++ R + C + +F F
Sbjct 2186 PTVREYVKWGMGKIVTPAKLLLLRDEKQEFVAPKVVKAKAIACYCAVKWFLLYCFSWIKF 2245
Query 2183 TRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLIN--------IIIW-- 2232
N+ K T +A K K C A N L++ N+S + ++W
Sbjct 2246 ----NTDNKVIYTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVFLLWFN 2298
Query 2233 FLLLSVCLGSL---------IYSTAALGVLMSNLGMPSYCTGYRE---GYLNSTNVTIAT 2280
FL +V L + + + G+ + C Y+ GY +S
Sbjct 2299 FLYANVILSDFYLPNIGPLPTFVGQIVAWFKTTFGVSTICDFYQVTDLGYRSS------- 2351
Query 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLTAFGLVAEWFLAYILFTRF 2337
+C GS+ C +C SG D LD Y ++ +Q + SF + ++ F LV E + Y L+T
Sbjct 2352 FCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRLSFDY-ISLFKLVVELVIGYSLYTVC 2410
Query 2338 FYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWK 2395
FY L + MQL ++ F+ + W L + + M P ++R YI + Y V+
Sbjct 2411 FYPLFVLIGMQLLTTWLPEFFMLETMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVYC 2470
Query 2396 SYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNC 2455
HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC+NC
Sbjct 2471 LCRHVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLNC 2530
Query 2456 DTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYER 2515
+++ G+TFI+ E A DLS + KRP+NPTD + Y V V S+ L++++ GQ+ Y+
Sbjct 2531 NSWKPGNTFITHEAAADLSKELKRPVNPTDSAYYSVTEVKQVGCSMRLFYERDGQRVYDD 2590
Query 2516 HSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQA 2575
+ S FV+++ L + KG +V+V + ++ +++ A+V+Y+Q + +P+L++++
Sbjct 2591 VNASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLGAAVFYAQSLYRPMLMVEKK 2648
Query 2576 LVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFIS 2635
L++ V+ MFD YV++ + +V + L + V A L + V L+ V+ TFI
Sbjct 2649 LITTANTGLSVSRTMFDLYVDSLLNVLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFIG 2708
Query 2636 AARQG-FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDC 2694
AR+ +DSDVETK + + + + + ++ T +SCNN + TY K + + DLG I
Sbjct 2709 CARRKCAIDSDVETKSITKSVMSAVNAGVDFTDESCNNLVPTYVKSDTIVAADLGVLIQN 2768
Query 2695 SARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVV 2754
+A+H+ A VAK+ N+A IW+V F LS L+ ++R A K L KLT V ++
Sbjct 2769 NAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQEANVPIL 2828
Query 2755 TTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDG 2814
TT +LKGG + + L+ L L+ V + + P + + K +K ID
Sbjct 2829 TTPFSLKGGAVFSRMLQWLFVANLICFIV---LWALMPTYAVHKSDMQLPLYASFKVIDN 2885
Query 2815 GVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGT 2872
GV RD++ TD CFANK FD W+ G Y N KACP++ AVI +++G + +P T
Sbjct 2886 GVLRDVSVTDACFANKFNQFDQWYESTFGLAYYRNSKACPVVVAVIDQDIGHTLFNVPTT 2945
Query 2873 ILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPY 2932
+LR LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P PY
Sbjct 2946 VLR-YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHPY 3004
Query 2933 CYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCER 2991
CY V+ + Y SL P RY L + I+FP EG VRVV T YCR G CE
Sbjct 3005 CYTGGVMHNASLYSSLAPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLCEE 3064
Query 2992 SEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGG 3051
+E G+C + + WVLNN YYR++PG FCG +A +L+ + L++PI ++AS VAG
Sbjct 3065 AEEGICFNFNRSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALTASSVAGA 3124
Query 3052 IVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLY 3111
I+AI+V YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L +Y+ Y Y
Sbjct 3125 ILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFY 3184
Query 3112 LTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVS 3171
T Y +++S + H+QW+VM+ ++P W I Y+ + + H W FS R++ S
Sbjct 3185 TTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFS--YCRKIGTEVRS 3242
Query 3172 FSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAAC 3231
TFEE AL TF++ KE Y KL++ V +NRYL+LYNKY+YFSG MDT +YREAAC
Sbjct 3243 DGTFEEMALTTFMITKESYCKLKNSV--SDVAFNRYLSLYNKYRYFSGKMDTAAYREAAC 3300
Query 3232 CHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTL 3290
LAKA+ F+ N+G+DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G TL
Sbjct 3301 SQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCIVSVTYGNMTL 3360
Query 3291 NGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVL 3350
NGLWLDD VYCPRHVIC+S DM +P+Y +LL R ++ +F V +G + L V+ + MQ C L
Sbjct 3361 NGLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSGRMSLTVMSYQMQGCQL 3420
Query 3351 KLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGS 3410
L V NP TPKY F ++PG+TF+VLA YNG P G + +R + TIKGSFL GSCGS
Sbjct 3421 VLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVTLRSSHTIKGSFLCGSCGS 3480
Query 3411 VGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAW 3470
VG+ + D V F YMH +EL TG H GTD GNFYGP+ D Q Q D T TVNV+AW
Sbjct 3481 VGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAW 3540
Query 3471 LYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAS 3530
LYAA+ N WF+ + +L +FN+ AM + + D V L L++ TG+ V + A+
Sbjct 3541 LYAAIFNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVLAA 3598
Query 3531 LKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTS 3590
+K L +G G+ ILGS +LEDE TP DV +Q +GV QS R IKGT W+L +
Sbjct 3599 IKR-LHSGFQGKQILGSCVLEDE-TPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTFLF 3656
Query 3591 LLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYF 3650
++ +W++F ++ + L + + +FAM+ +KHKH +L ++++P L T
Sbjct 3657 CSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLIKHKHLYLTMYIMPVLCTFYTN 3715
Query 3651 NMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILM---TARTVYDDGARR 3707
+V S+ WL ++ + D V+Y VVLL+ M T R++ D
Sbjct 3716 YLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLY--GVVLLVAMVFVTMRSINHDVFSI 3772
Query 3708 VWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARG-IVFMCVEYC 3766
++ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA ++ +
Sbjct 3773 MFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKWLAVN 3828
Query 3767 PIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQ 3826
++F ++ ++L Y +GY C CY+G+ LLN FR+ LGVY+Y +S QE RYMN+
Sbjct 3829 VLYFTDVPQIKLVLLSYLCIGYVCCCYWGILSLLNSIFRMPLGVYNYKISVQELRYMNAN 3888
Query 3827 GLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSK 3886
GL PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+SK
Sbjct 3889 GLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNSK 3948
Query 3887 LWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRAT 3940
LW C LHN+IL D + AF+K+ LL VL + AVD I ++ ++ + +
Sbjct 3949 LWQYCSTLHNEILATSDLSMAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNTV 4008
Query 3941 LQAIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQR 3999
LQA+ SEF ++ S+ + A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ R
Sbjct 4009 LQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVAR 4068
Query 4000 KLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPL 4059
KLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPL
Sbjct 4069 KLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPL 4128
Query 4060 NIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNS 4119
N IP T+ L +++PD + D TYA +W IQ + DAD + QL+EI ++++
Sbjct 4129 NAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDVNST 4188
Query 4120 PNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKG 4177
WPL++ A R N S V LQNNEL P LR +G+ T YYNTT
Sbjct 4189 ----WPLVIAANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQ--CYYNTTGT 4242
Query 4178 GRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNL 4237
G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L
Sbjct 4243 GKIVYAILSDCDGLKYTKIVKEDGN-CVVLELDPPCKFSVQDVKGLKIKYLYFVKGCNTL 4301
Query 4238 NRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKM 4297
RG V+G+L++TVRLQAG ATE +NS +LS CAF+VD K Y DY+ GG P+TNCVKM
Sbjct 4302 ARGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIKQGGVPVTNCVKM 4361
Query 4298 LCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCA 4357
LC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P
Sbjct 4362 LCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-I 4420
Query 4358 NDPVGFTLKNTVCTVCGMWKGYGCSC 4383
DPV + L + VC VCG W+ CSC
Sbjct 4421 KDPVSYVLTHDVCQVCGFWRDGSCSC 4446
Score = 79.3 bits (194), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 67/252 (27%), Positives = 118/252 (47%), Gaps = 20/252 (8%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T NV D+++ + V V+VN AN + HG GVAGA+ + +A E+ D +
Sbjct 1320 ITPNVCFVKGDVIKVVRLVNAEVIVNPANGRMAHGAGVAGAIAEKAGSAFIKETSDMVKA 1379
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENFNQHEVLLAPLLS 1150
G +VG +G L K L++VGP+ +G Q LL+ AY++ N+ + ++ L+S
Sbjct 1380 QGVCQVGECYESAGGKLCKKVLNIVGPDA-RGHGKQCYSLLERAYQHINKCDNVVTTLIS 1438
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + V NV L +++ +D + + K + ++A+
Sbjct 1439 AGIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFDVIEKCQVTSVAGTKALSLQLAKNLCR 1498
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+VK F+T + S+ ++C L+E + L ++ L ++ N +
Sbjct 1499 DVK-FVTNACSSLFS--------ESCFVSSYDVLQEVEALRHDIQLDDDARVFVQANMDC 1549
Query 1264 HPDSATLVSDID 1275
P LV+ D
Sbjct 1550 LPTDWRLVNKFD 1561
Score = 73.6 bits (179), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 108/457 (24%), Positives = 188/457 (41%), Gaps = 59/457 (13%)
Query 569 ILDGISQYSLRLIDA-MMFTSDLA------TNNLVVMAYITGGVVQLTSQWLTNIFGTVY 621
+LDG+ S LI + FTS + T+ + MA + V++ ++++ + G +
Sbjct 576 LLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMALLFMHDVKVATKYVKKVTGKLA 635
Query 622 EKLKPVLDWLEEKFKEGVEFLRD------GWEIVKFISTCACEIVGGQIVTCAKEIKESV 675
+ K + + K E + D GW + ++ V ++T +E+ E V
Sbjct 636 VRFKALGVAVVRKITEWFDLAVDIAASAAGWLCYQLVN--GLFAVANGVITFVQEVPELV 693
Query 676 QTFFKLVNKFLALCADSI---IIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMP 732
+ F F + DS+ I+ G + + SK +Y V + + +MP
Sbjct 694 KNFVDKFKAFFKVLIDSMSVSILSGLTVVKTASNRVCLAGSK-VYE--VVQKSLSAYVMP 750
Query 733 LKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTPVCINGLML 790
+ E L GE P V + + ++ P + + P +CI +
Sbjct 751 VGC-SEATCLVGEIEPA-------VFEDDVVDVVKAPLTYQGCCKPPTSFEKICIVDKLY 802
Query 791 LEIKDTEKYCALAPN--MMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGYKSVNITFELDE 847
+ + Y + N + V + + A KV F D V ++ + + ITF LD
Sbjct 803 MAKCGDQFYPVVVDNDTVGVLDQCWRFPC-AGKKVEFNDKPKVRKIPSTRKIKITFALDA 861
Query 848 RIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPLGIDLDEWSMAT 904
D VL++ CS + V+ ++E VV DAV TL P E + T + LD +
Sbjct 862 TFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEHDVIGTKVCALLDRLAGDY 921
Query 905 YYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGA 964
YLFDE G+ +A MYCSF PD++ DC + + + + +DD A
Sbjct 922 VYLFDEGGDEVIAPRMYCSFSAPDDE----DCVAADVVDADENQ---DDD---------A 965
Query 965 TSAALQPEEEQEED-----WLDDDSQQTVGQQDGSED 996
+A+ + QEED ++ DS+ V E+
Sbjct 966 EDSAVLVADTQEEDGVAKGQVEADSEICVAHTGSQEE 1002
>sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=1a PE=3 SV=1
Length=4421
Score = 1825 bits (4727), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1057/2870 (37%), Positives = 1582/2870 (55%), Gaps = 122/2870 (4%)
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1600 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1659
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1660 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1718
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1719 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1778
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF+
Sbjct 1779 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPFL 1836
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ + G GHY H+ D + K + G +TD
Sbjct 1837 ICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLTD 1894
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--N 1922
Y +N + T T Y LD V +P L YY + Y+T +PI +P+ +
Sbjct 1895 CLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKVD 1953
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I LN G+ E KVT +P GDVV Y + K
Sbjct 1954 GVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2011
Query 1982 GAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNL 2039
G + KP++W H + N TY ++ ++ N + VL +D++
Sbjct 2012 GCETFGKPVIWFCHDEASLNSLTY----------FNKPSFKSENRYSVLS------VDSV 2055
Query 2040 ACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAA 2098
+ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2056 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2115
Query 2099 YVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTN 2155
Y+ + NELSR++ T+ +G+ + ++P D + T
Sbjct 2116 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRD--------DNQTL 2166
Query 2156 IVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASF 2215
+V + + + L + + + TN + T IA ++ L+ +F
Sbjct 2167 LVPKIFKARAIEFYGFLKWLFIYVFSLLHFTNDK-TIFYTTEIASKFTFNLFCLALKNAF 2225
Query 2216 NYLKSPNFSKLINII-----IWF--LLLSVCLGSL---------IYSTAALGVLMSNLGM 2259
+ F K ++ WF L ++V I+ + + + G+
Sbjct 2226 QTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGL 2285
Query 2260 PSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISS---FKW 2316
+ C Y + + T + +C GS C +C SG D LDTY +++ +Q + F +
Sbjct 2286 VTICDFYSKLGVGFT----SHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDY 2341
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2342 -VSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2400
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2401 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2460
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2461 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2520
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + S + ++
Sbjct 2521 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVE--SDADRANF 2578
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2579 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQIMFDVYVDTFMSHFDVDRKSFNNFVN 2638
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2639 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2698
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK NI+ IW + F L+ L+ +++ A
Sbjct 2699 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKVANISCIWFIDAFNQLTADLQHKLKKAC 2758
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L ++L+ + + + P
Sbjct 2759 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPT 2815
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGS--YTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ GS Y N C
Sbjct 2816 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDC 2875
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2876 PIVVAVMDEDIGSTMFNVPTKVLRY-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2934
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2935 GCVLSSLCTMFKRGDGTPHPYCYTDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 2994
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 2995 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDFFDLFYQF 3054
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3055 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFL 3114
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3115 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3174
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N S STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3175 NHVLWLFS--YCRKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3230
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3231 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3290
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R + +F
Sbjct 3291 VSPTSKIEPCLVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDF 3350
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3351 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAF 3410
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3411 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFNGNFYGPYR 3470
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM + + D
Sbjct 3471 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADL 3530
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3531 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3587
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3588 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3646
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3647 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYEVFYGCIL 3706
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3707 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3762
Query 3749 TTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3763 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3822
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3823 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKC 3882
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD- 3926
+VVLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL S AVD
Sbjct 3883 ANVVLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFSNPAAVDT 3942
Query 3927 -----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKL 3980
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L
Sbjct 3943 KCLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQL 4002
Query 3981 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4040
+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKL
Sbjct 4003 EKACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKL 4062
Query 4041 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQ 4100
DN ALN+I++NA GCVPL+ IP A L ++IPD + D TYA ++W IQ
Sbjct 4063 DNQALNSILDNAVKGCVPLSAIPALAANTLTIIIPDKQVFDKVVDNVYVTYAGSVWHIQT 4122
Query 4101 VVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGT 4158
V DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4123 VQDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGS 4178
Query 4159 -----TQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPC 4213
T C YYN GR V A+LSD+ LK+ + K DG + EL+PPC
Sbjct 4179 DINCNIPTQC-------YYNNVSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPC 4230
Query 4214 RFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFA 4273
+F KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+
Sbjct 4231 KFSIQDVKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFS 4290
Query 4274 VDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCH 4333
VD K Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR
Sbjct 4291 VDPKKTYLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRAR 4350
Query 4334 IDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSC 4383
++HP+ G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC
Sbjct 4351 VEHPDVDGICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSC 4399
Score = 82.0 bits (201), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 53/155 (34%), Positives = 79/155 (51%), Gaps = 2/155 (1%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A E+ +
Sbjct 1308 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1367
Query 1092 ATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHEVLLAPLL 1149
+ G +VG V +G L K L++VGP+ + + LL AY++ N ++ L+ L+
Sbjct 1368 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1427
Query 1150 SAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
SAGIF SL + V V L +K +D
Sbjct 1428 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFD 1462
Score = 73.9 bits (180), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 103/422 (24%), Positives = 171/422 (41%), Gaps = 63/422 (15%)
Query 562 LQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW-------- 612
L ++ I +SQ+S + D + L + + V YI V +L +Q+
Sbjct 562 LIQSGIFFTSLMSQFSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLV 621
Query 613 --LTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKE 670
+ N F T+ + P WL + G F+ + A I AK
Sbjct 622 NKMVNWFNTMLDASAPATGWLLYQLLNGF-----------FVVSQANLNFVALIPDYAKI 670
Query 671 IKESVQTFFKLVNKFLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSRE 725
+ TFFKL+ L ++ LK +N +G F S GL
Sbjct 671 LVNKFYTFFKLL---LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI-------- 719
Query 726 ETGLLMPLKA-PKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTP 782
G ++P A ++I F EG + E V+++ ++ ++ S E + P
Sbjct 720 -PGFVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEK 771
Query 783 VCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGG-----APTKVTFGDDTVI-EVQGY 836
+CI M + K +K+ P +M N L A KV F + V+ E+
Sbjct 772 ICIIDNMYMG-KCGDKF---FPIVMNDKNICLLDHAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 837 KSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPL 893
+V + F+LD D +L + CS + VE G V++F VV DA+ L E + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQV 887
Query 894 GIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTE 952
L++ + YLFDE+G+ +AS MYC+F D ED + E+ + + +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 953 DD 954
+D
Sbjct 948 ED 949
Score = 44.3 bits (103), Expect = 0.060, Method: Compositional matrix adjust.
Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 16/148 (11%)
Query 1658 YPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAY 1717
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1095 YFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTT 1154
Query 1718 CNKTV--GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
K + + G V + + ++++ N C CG L G++AV + G +
Sbjct 1155 IPKAIVLPQGGYVADFAYWFLNQFDINA---YANWCCLKCG-FSFDLNGLDAVFFYGDI- 1209
Query 1776 YEQFKKGVQIPCTCGKQATKYLVQQESP 1803
V C CG T L+ + P
Sbjct 1210 -------VSHVCKCGHNMT--LIAADLP 1228
>sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=1a PE=3 SV=1
Length=4441
Score = 1823 bits (4721), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1052/2865 (37%), Positives = 1581/2865 (55%), Gaps = 112/2865 (4%)
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1620 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1679
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1680 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1738
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1739 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1798
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF+
Sbjct 1799 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPFL 1856
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ + G GHY H+ D + K + G +TD
Sbjct 1857 ICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLTD 1914
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--N 1922
Y +N + T T Y LD V +P L YY + Y+T +PI +P+ +
Sbjct 1915 CLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKVD 1973
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I LN G+ E KVT +P GDVV Y + K
Sbjct 1974 GVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2031
Query 1982 GAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNL 2039
G + KP++W H + N TY ++ ++ N + VL +D++
Sbjct 2032 GCETFGKPVIWLCHDEASLNSLTY----------FNKPSFKSENRYSVLS------VDSV 2075
Query 2040 ACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAA 2098
+ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2076 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2135
Query 2099 YVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTN 2155
Y+ + NELSR++ T+ +G+ + ++P D + T
Sbjct 2136 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRD--------DNQTL 2186
Query 2156 IVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASF 2215
+V + + + L + + + TN + T IA ++ L+ +F
Sbjct 2187 LVPKIFKARAIEFYGFLKWLFIYVFSLLHFTNDK-TIFYTTEIASKFTFNLFCLALKNAF 2245
Query 2216 NYLKSPNFSKLINII-----IWF--LLLSVCLGSL---------IYSTAALGVLMSNLGM 2259
+ F K ++ WF L ++V I+ + + + G+
Sbjct 2246 QTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGL 2305
Query 2260 PSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISS---FKW 2316
+ C Y + + T + +C GS C +C SG D LDTY +++ +Q + F +
Sbjct 2306 VTICDFYSKLGVGFT----SHFCNGSFICELCYSGFDMLDTYAAIDFVQYEVDRRVLFDY 2361
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2362 -VSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2420
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2421 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2480
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2481 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2540
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + S + ++
Sbjct 2541 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVE--SDADRANF 2598
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2599 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVN 2658
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2659 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2718
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK+ NI+ IW + F L+ L+ +++ A
Sbjct 2719 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDTFNQLTADLQHKLKKAC 2778
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L ++L+ + + + P
Sbjct 2779 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPT 2835
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGS--YTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ GS Y N C
Sbjct 2836 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSFYYHNSMDC 2895
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2896 PIVVAVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2954
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2955 GCVLSSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 3014
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 3015 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQF 3074
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3075 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFL 3134
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3135 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3194
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N + STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3195 NHVLWLFS--YCRKIGVNVCNDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3250
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3251 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3310
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R + +F
Sbjct 3311 VSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDF 3370
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3371 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAF 3430
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3431 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYR 3490
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM + + D
Sbjct 3491 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADL 3550
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3551 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3607
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+ V
Sbjct 3608 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLV 3666
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3667 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGLTYVWLSYFVPAVNFTYVYEVFYGCIL 3726
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3727 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW-- 3782
Query 3749 TTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLT 3807
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR+
Sbjct 3783 TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMP 3842
Query 3808 LGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKC 3867
+GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3843 MGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKC 3902
Query 3868 TSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD- 3926
+VVLL+ LQ L V S+S+LW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3903 ANVVLLNCLQHLHVASNSRLWQYCSILHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDT 3962
Query 3927 -----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKL 3980
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L
Sbjct 3963 KCLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQL 4022
Query 3981 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4040
+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKL
Sbjct 4023 EKACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKL 4082
Query 4041 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQ 4100
DN ALN+I++NA GCVPLN IP A L ++IPD + D YA ++W IQ
Sbjct 4083 DNQALNSILDNAVKGCVPLNAIPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQT 4142
Query 4101 VVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGT 4158
V DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4143 VQDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGS 4198
Query 4159 TQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTD 4218
+ YYN GR V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4199 DMNC--NIPTQCYYNNGSSGRIVYAVLSDVDGLKYTKIIKDDGNCVV-LELDPPCKFSIQ 4255
Query 4219 TPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK 4278
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VD K
Sbjct 4256 DVKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKK 4315
Query 4279 AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPN 4338
Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+
Sbjct 4316 TYLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPD 4375
Query 4339 PKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSC 4383
G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC
Sbjct 4376 VDGLCKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSC 4419
Score = 81.6 bits (200), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 53/155 (34%), Positives = 79/155 (51%), Gaps = 2/155 (1%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A E+ +
Sbjct 1328 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1387
Query 1092 ATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHEVLLAPLL 1149
+ G +VG V +G L K L++VGP+ + + LL AY++ N ++ L+ L+
Sbjct 1388 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1447
Query 1150 SAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
SAGIF SL + V V L +K +D
Sbjct 1448 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFD 1482
Score = 72.8 bits (177), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 102/422 (24%), Positives = 172/422 (41%), Gaps = 63/422 (15%)
Query 562 LQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW-------- 612
L ++ I +SQ+S + D + L + + V YI V +L +Q+
Sbjct 562 LIQSGIFFTSLMSQFSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLV 621
Query 613 --LTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKE 670
+ N F T+ + P WL + G+ F+ + A I AK
Sbjct 622 NKMVNWFNTMLDASAPATGWLLYQLLNGL-----------FVVSQANFNFVALIPDYAKI 670
Query 671 IKESVQTFFKLVNKFLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSRE 725
+ TFFKL+ L ++ LK +N +G F S GL
Sbjct 671 LVNKFYTFFKLL---LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI-------- 719
Query 726 ETGLLMPLKA-PKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTP 782
G ++P A ++I F EG + E V+++ ++ ++ S E + P
Sbjct 720 -PGFVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEK 771
Query 783 VCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGG-----APTKVTFGDDTVI-EVQGY 836
+CI M + K +K+ P +M N L A KV F + V+ E+
Sbjct 772 ICIIDNMYMG-KCGDKF---FPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 837 KSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPL 893
+V + F+LD D +L + CS + VE G V++F VV DA+ L + + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKDHPVVGYQV 887
Query 894 GIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTE 952
L++ + YLFDE+G+ +AS MYC+F D ED + E+ + + +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 953 DD 954
+D
Sbjct 948 ED 949
Score = 44.3 bits (103), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 16/148 (11%)
Query 1658 YPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAY 1717
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1115 YFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTT 1174
Query 1718 CNKTV--GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
K + + G V + + ++++ N C CG L G++AV + G +
Sbjct 1175 IPKAIVLPQGGYVADFAYWFLNQFDINA---YANWCCLKCG-FSFDLNGLDAVFFYGDI- 1229
Query 1776 YEQFKKGVQIPCTCGKQATKYLVQQESP 1803
V C CG T L+ + P
Sbjct 1230 -------VSHVCKCGHNMT--LIAADLP 1248
>sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=1a PE=1 SV=1
Length=4471
Score = 1818 bits (4709), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1057/2867 (37%), Positives = 1582/2867 (55%), Gaps = 116/2867 (4%)
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1650 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1709
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1710 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1768
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1769 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1828
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF+
Sbjct 1829 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPFL 1886
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ + G GHY H+ D + K + G +TD
Sbjct 1887 ICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLTD 1944
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--N 1922
Y +N + T T Y LD V +P L YY + Y+T +PI +P+ +
Sbjct 1945 CLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKVD 2003
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYKKPAS-RELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I LN G+ E KVT +P GDVV Y + K
Sbjct 2004 GVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2061
Query 1982 GAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNL 2039
G + KP++W H + N TY ++ ++ N + VL +D++
Sbjct 2062 GCETFGKPVIWFCHDEASLNSLTY----------FNKPSFKSENRYSVLS------VDSV 2105
Query 2040 ACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAA 2098
+ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2106 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2165
Query 2099 YVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTN 2155
Y+ + NELSR++ T+ +G+ + ++P D + N+ +
Sbjct 2166 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRDD---NQTLLVPKI 2221
Query 2156 IVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCL--EA 2213
R + ++ + F + L FT + + N FCL +
Sbjct 2222 FKARAIEFY--GFLKWLFIYVFSLLHFTNDKTIFYTTEIASKFTFNL------FCLALKN 2273
Query 2214 SFNYLKSPNFSKLINII-----IWF--LLLSVCLGSL---------IYSTAALGVLMSNL 2257
+F + F K ++ WF L ++V I+ + + +
Sbjct 2274 AFQTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATF 2333
Query 2258 GMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISS---F 2314
G+ + C Y + + T + +C GS C +C SG D LDTY +++ +Q + F
Sbjct 2334 GLVTICDFYSKLGVGFT----SHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLF 2389
Query 2315 KWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLV 2372
+ ++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ +
Sbjct 2390 DY-VSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVA 2448
Query 2373 QMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRR 2432
M P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R
Sbjct 2449 NMLPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIR 2508
Query 2433 SFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVD 2492
+ + ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V
Sbjct 2509 YYDITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVT 2568
Query 2493 SVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES 2552
+ + L++D+ GQ+ Y+ S FV+++NL + K + V+V +S + +
Sbjct 2569 DIKQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVV--VESDADRA 2626
Query 2553 SAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTL 2612
+ +A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V +
Sbjct 2627 NFLNAVVFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNF 2686
Query 2613 VATAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCN 2671
V A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ N
Sbjct 2687 VNIAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYN 2746
Query 2672 NYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRS 2731
N + TY K +N+ DLG I A+H+ VAK+ NI+ IW + F L+ L+ +++
Sbjct 2747 NLVPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDAFNQLTADLQHKLKK 2806
Query 2732 AAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLIT 2791
A K L KLT V ++TT +LKGG +++N L L V+L+ + + +
Sbjct 2807 ACVKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFVSLICFI---LLWALL 2863
Query 2792 PVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGS--YTNDK 2849
P + + K +K ID GV RDI+ D CFANK FD W+ GS Y N
Sbjct 2864 PTYSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSM 2923
Query 2850 ACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFA 2909
CP++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF
Sbjct 2924 DCPIVVAVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFY 2982
Query 2910 TSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTY 2968
S CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+
Sbjct 2983 ASGCVLSSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVI 3042
Query 2969 LEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLT 3028
EG VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 3043 SEGIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFY 3102
Query 3029 NMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMS 3088
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++
Sbjct 3103 QFFSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVVVWCIN 3162
Query 3089 FTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICI 3148
F +L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3163 FLMLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMV 3222
Query 3149 STKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYL 3208
H W FS R++ N S STFEE +L TF++ K+ Y +L++ V YNRYL
Sbjct 3223 IANHVLWLFS--YCRKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYL 3278
Query 3209 ALYNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFR 3267
+LYNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG
Sbjct 3279 SLYNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIV 3338
Query 3268 KMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNH 3327
KM P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC+S +M P+Y LL R +
Sbjct 3339 KMVSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICSSSNMNEPDYSALLCRVTLG 3398
Query 3328 NFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSG 3387
+F + +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G
Sbjct 3399 DFTIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGNVKPGETFTVLAAYNGRPQG 3458
Query 3388 VYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGP 3447
+ MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP
Sbjct 3459 AFHVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGP 3518
Query 3448 FVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQ 3507
+ D Q Q D TVNV+AWLYAA++N WF+ + DFN+ AM + +
Sbjct 3519 YRDAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSTEDFNVWAMANGFSQVKA 3578
Query 3508 DHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVT 3567
D V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV
Sbjct 3579 DLV--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVK 3635
Query 3568 FQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMM 3627
QS KR IK T +W+L++ ++ +W++F ++ + + ++ +F M+
Sbjct 3636 LQSKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMML 3694
Query 3628 FVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYA 3686
VKHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3695 LVKHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSYFVPAVNFTYVYEVFYGC 3754
Query 3687 SAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSG 3746
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3755 ILCVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTW 3812
Query 3747 VVTTVMFLARGIVFMCVEYCPIFFITG-NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 3805
TT++ LA + IF+ T ++ I+L Y F+GY +CY+G F LLN FR
Sbjct 3813 --TTILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFR 3870
Query 3806 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDV 3865
+ +GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DV
Sbjct 3871 MPMGVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDV 3930
Query 3866 KCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAV 3925
KC +VVLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL + AV
Sbjct 3931 KCANVVLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFANPAAV 3990
Query 3926 D------INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLK 3978
D I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K
Sbjct 3991 DTKCLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIK 4050
Query 3979 KLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLR 4038
+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+R
Sbjct 4051 QLEKACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVR 4110
Query 4039 KLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEI 4098
KLDN ALN+I++NA GCVPL+ IP A L +VIPD + D TYA ++W I
Sbjct 4111 KLDNQALNSILDNAVKGCVPLSAIPALAANTLTIVIPDKQVFDKVVDNVYVTYAGSVWHI 4170
Query 4099 QQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAA 4156
Q V DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +
Sbjct 4171 QTVQDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNS 4226
Query 4157 GTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFV 4216
G+ + YYN GR V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4227 GSDMNC--NIPTQCYYNNGSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFS 4283
Query 4217 TDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDA 4276
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VD
Sbjct 4284 IQDVKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDP 4343
Query 4277 AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDH 4336
K Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++H
Sbjct 4344 KKTYLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEH 4403
Query 4337 PNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSC 4383
P+ G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC
Sbjct 4404 PDVDGICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSC 4449
Score = 81.6 bits (200), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 53/155 (34%), Positives = 79/155 (51%), Gaps = 2/155 (1%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A E+ +
Sbjct 1358 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1417
Query 1092 ATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHEVLLAPLL 1149
+ G +VG V +G L K L++VGP+ + + LL AY++ N ++ L+ L+
Sbjct 1418 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1477
Query 1150 SAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYD 1184
SAGIF SL + V V L +K +D
Sbjct 1478 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFD 1512
Score = 74.3 bits (181), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 103/422 (24%), Positives = 172/422 (41%), Gaps = 63/422 (15%)
Query 562 LQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW-------- 612
L ++ I +SQ+S + D + L + + V YI V +L +Q+
Sbjct 562 LIQSGIFFTSLMSQFSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLV 621
Query 613 --LTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKE 670
+ N F T+ + P WL + G+ F+ + A I AK
Sbjct 622 NKMVNWFNTMLDASAPATGWLLYQLLNGL-----------FVVSQANFNFVALIPDYAKI 670
Query 671 IKESVQTFFKLVNKFLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSRE 725
+ TFFKL+ L ++ LK +N +G F S GL
Sbjct 671 LVNKFYTFFKLL---LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI-------- 719
Query 726 ETGLLMPLKA-PKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTP 782
G ++P A ++I F EG + E V+++ ++ ++ S E + P
Sbjct 720 -PGFVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEK 771
Query 783 VCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGG-----APTKVTFGDDTVI-EVQGY 836
+CI M + K +K+ P +M N L A KV F + V+ E+
Sbjct 772 ICIIDNMYMG-KCGDKF---FPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 837 KSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPL 893
+V + F+LD D +L + CS + VE G V++F VV DA+ L E + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQV 887
Query 894 GIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTE 952
L++ + YLFDE+G+ +AS MYC+F D ED + E+ + + +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 953 DD 954
+D
Sbjct 948 ED 949
Score = 43.1 bits (100), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 36/148 (24%), Positives = 64/148 (43%), Gaps = 16/148 (11%)
Query 1658 YPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAY 1717
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1145 YFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTT 1204
Query 1718 CNKTV--GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
K + + G V + + ++++ N C CG L G++A+ + G +
Sbjct 1205 IPKAIVLPQGGFVADFAYWFLNQFDINA---YANWCCLKCG-FSFDLNGLDALFFYGDI- 1259
Query 1776 YEQFKKGVQIPCTCGKQATKYLVQQESP 1803
V C CG T L+ + P
Sbjct 1260 -------VSHVCKCGHNMT--LIAADLP 1278
>sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus
512/2005 OX=693999 GN=1a PE=3 SV=1
Length=4128
Score = 1228 bits (3177), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 791/2267 (35%), Positives = 1217/2267 (54%), Gaps = 160/2267 (7%)
Query 2171 YFFTLLLQLCTFTRSTNSRIKASMPT---TIAKNTVK---SVGKFCLEASFNYLKSPNFS 2224
Y F+LL + + ++ A +P I K +VK KF F Y+K
Sbjct 1984 YLFSLLAICFRALKKRDMKVMAGVPERTGIILKRSVKYNYKALKFFFRLKFQYIKV---- 2039
Query 2225 KLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTG 2284
FL S+ L +L Y+ + + + +G P C Y +GY NST YC G
Sbjct 2040 --------FLKFSLVLYTL-YALMFMFIRFTPVGTP-ICKRYTDGYANST-FDKNDYC-G 2087
Query 2285 SIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLA 2344
++ C +CL G + L + I K L L + + I+F FF +G+
Sbjct 2088 NVLCKICLYGYEELSDFTHTRVIW---QHLKDPLIGNILPLFYLVFLIIFGGFFVRIGIT 2144
Query 2345 AIMQLFFSY--FAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVD 2402
+ + + A+ + N WL+ L+ P ++M + + + HV+
Sbjct 2145 YFIMQYINAAGVALGYQDNVWLLHLL-------PFNSMGNIIVVAFIVTRILLFLKHVLF 2197
Query 2403 GCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGS 2462
GC+ +C+ C K + TRV TI+ GV +SFYV ANGGK FCK HN+ CV+CD++ G
Sbjct 2198 GCDKPSCIACSKSAKLTRVPLQTILQGVTKSFYVNANGGKKFCKKHNFFCVDCDSYGYGC 2257
Query 2463 TFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFV 2522
TFI+D +A +LS K + PT ++ I+D V NG +LY K + + +
Sbjct 2258 TFINDVIAPELSNVTKLNVIPTGPATIIIDKVEFSNGFYYLYSGSTFWKYNFDITEAKYA 2317
Query 2523 NLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGD 2582
D L+ N + + +VF+ S + K+A VY+SQL+C+PI L+D AL++ +
Sbjct 2318 CKDVLKNCN----ILTDFVVFN-NSGSNVTQVKNACVYFSQLLCKPIKLVDSALLASL-- 2370
Query 2583 SAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFV 2642
+ + + + A+V S++F + + + R+
Sbjct 2371 NVDFSANLHKAFVEVLSNSFGKDLSNCSNM----------------------NECRESLG 2408
Query 2643 DSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVE-NMTPRDLGACIDCSARHINA 2701
SDV ++ + +H+ D+ ++ S NN +++Y K E + D+ C+ A+ +N
Sbjct 2409 LSDVPEEEFSAAVSEAHRYDVLISDVSFNNLIVSYAKPEEKLAVHDIANCMRVGAKVVNH 2468
Query 2702 QVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALK 2761
V N+ ++W KDF++LSE+ RK I K + F LT R + + T +A K
Sbjct 2469 NVLTKDNVPVVWLAKDFIALSEEARKYIVRTTKTKGINFMLTFNDRRMHLTIPTISVANK 2528
Query 2762 GGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIG-----YKAIDGGV 2816
G + + +L + F + LI + V + DFS+++ +K I+ GV
Sbjct 2529 KGAGLPSLFTRL------YSFFWHLCVLIVVLFVATSLLDFSAQVTSDTQYDFKYIENGV 2582
Query 2817 TRDIASTDTCFANKHADFDTWFSQRGGSY-TNDKACPLIAAVITREVGFVVPGLPGTILR 2875
+ C N +F+ W + + GS TN + CP++ + EV ++ PG+P +
Sbjct 2583 LKVFEKPLDCVHNAFVNFNEWHNAKFGSIPTNSRRCPIVVGT-SDEVRYI-PGVPAGVF- 2639
Query 2876 TTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYD 2935
G L F +C+ L + +C+ + CT G+ V YCY
Sbjct 2640 -LYGKSLIFAMSTIFGTSGLCFDDRGLTD-----PDSCIFNSACTTLSGIGGRNV-YCYR 2692
Query 2936 TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCERSEA 2994
V++ + Y SL P + Y LMDG+ I P G +R + T YCR G C S+A
Sbjct 2693 EGVVDNAKLYSSLLPHSYYRLMDGNHIVLPEIITRGFGIRTIKTQAMTYCRTGECIDSQA 2752
Query 2995 GVCVSTSGRWVLNNDYYRSLPG--VFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGI 3052
GVCV +V Y PG CG +LL N+ I +S I+ +
Sbjct 2753 GVCVGLDRFFV-----YSKTPGSDYVCGTGFFSLLFNVIGMFSNSIPVTVMSGQILLNCV 2807
Query 3053 VAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYL 3112
VA + F +F+R FG+ S F L + V L+ V + + + Y L
Sbjct 2808 VAFTAVMACFAFTKFKRLFGDMS----FGVLSVGLCTVVNNLSYVVT-QNSIGMLAYATL 2862
Query 3113 TFYLTNDV--SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VF 3167
F T V S++ H+ + + + L P+W+ +AY+IC + F N K +V +F
Sbjct 2863 YFLCTKGVRYSWVWHVGFAISYCFLAPWWVVLAYLICALLE----FLPNLFKLKVSTQLF 2918
Query 3168 NGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSY 3226
G F +FE AA TF+L+ Y KL + + + +Y A YN+YKY+SG+ Y
Sbjct 2919 EGDKFVGSFESAASGTFVLDMHSYQKLANSI--STEKLKQYCASYNRYKYYSGSASEADY 2976
Query 3227 REAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCG 3286
R A HLAKA++DF+N D LY PP S S LQ+G RKMA PSG VEGC+V+V+ G
Sbjct 2977 RLACFAHLAKAMSDFANDHMDKLYTPPTVSYNST-LQAGLRKMAQPSGIVEGCIVRVSYG 3035
Query 3287 TTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSM 3345
TLNGLWL D V CPRHVI + + ++++ ++ L+R HNF + +GN+ L VI SM
Sbjct 3036 NLTLNGLWLGDTVICPRHVIASNTTNVIDYDHAMSLVRL--HNFSISSGNMFLGVISASM 3093
Query 3346 QNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLN 3405
+ +L +KV+ +N TP Y + ++PG +F++LACY+GS +GVY MR N+TI+GSF++
Sbjct 3094 RGTLLHIKVNQSNVNTPNYTYKVLKPGDSFNILACYDGSAAGVYGVNMRTNYTIRGSFIS 3153
Query 3406 GSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITV 3465
G+CGS G+NI+ V FCYMHH+EL +G H G+D++G YG + D+ T Q G +T
Sbjct 3154 GACGSPGYNINNGVVEFCYMHHLELGSGCHVGSDMDGTMYGKYEDQPTLQIEGASNLVTE 3213
Query 3466 NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVL 3525
NV +WLY A+INGDRW+L+ + ++ +N A++ L +VD L A+TG+ V
Sbjct 3214 NVCSWLYGALINGDRWWLSSVSVGVDTYNEWALRNGMTAL--KNVDCFSLLVAKTGVDVG 3271
Query 3526 DMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSA-VKRTIKGTHHWLL 3584
+ AS+++L N G++ILG L DEFT +VV+Q GVT QS V R +
Sbjct 3272 RLLASIQKLHGN-FGGKSILGCTSLCDEFTLSEVVKQMYGVTLQSGKVSRAFRNA----- 3325
Query 3585 LTILTSLLVLVQSTQW--SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLP 3642
+I+ LL L S S F++ P + II S+ M+ VKHK FL L+LLP
Sbjct 3326 -SIVCCLLFLFLSEMLNHSKLFWINPGYITPVFLAIIVASSALMLLVKHKLLFLQLYLLP 3384
Query 3643 SLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYD 3702
SL V+ +N ++ + ++ D GF + + + ++ L T R +
Sbjct 3385 SLCIVSGYN-IFKDYHFYTYMLEEFDY-KVPFGGFNVTGVLNISLCCFVMGLHTFR--FL 3440
Query 3703 DGARRVWT-LMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFM 3761
++++ ++ VLT++Y YY + + LI++ S + T F+ +
Sbjct 3441 QTPNKIFSYVVAVLTVLYTYYY------STDVLGLILTSMSGF----TNYWFIGTATYKL 3490
Query 3762 CVEYCP--IFFITGNTLQCIMLVYCFLGYFCTC-YFGLFCLLNRYFRLTLGVYDYLVSTQ 3818
P + + ++ ++ +Y LGY C C Y+G +NR+ +LTLG Y++ VS
Sbjct 3491 ATYVLPHTSLLDSFDAIKAVVFLYLLLGY-CNCVYYGSLYWINRFCKLTLGCYEFKVSAA 3549
Query 3819 EFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQ 3878
EF+YM + GL P DA L++KL+GVGG+ IK+++VQSK++D+KCT+VVLL L
Sbjct 3550 EFKYMVANGLRAPTGVFDALILSLKLIGVGGRKTIKISSVQSKLTDLKCTNVVLLGCLSN 3609
Query 3879 LRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNR 3938
+ + ++S+ WA CV LHN I L D A E +++LL+ LS A +++L + ++
Sbjct 3610 MNIAANSREWAYCVDLHNKINLCNDAEAAQEMLLALLAFFLSKNSAFGVDELLDSYFNDS 3669
Query 3939 ATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQ 3998
+ LQ++A+ + +LPSY A+ TA+++YE A+ANG ++K+L+ ++NVAKSEFDR+A+ Q
Sbjct 3670 SVLQSVAATYVNLPSYLAYETARQSYEDALANGSPPQLVKQLRHAMNVAKSEFDREASTQ 3729
Query 3999 RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP 4058
RKL++MA+QA +QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I++ A+DG VP
Sbjct 3730 RKLDRMAEQAASQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLAKDGVVP 3789
Query 4059 LNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDN 4118
L+IIP +A KL +V+ D +Y YA +W + + D D K V E+ N
Sbjct 3790 LSIIPAVSATKLNIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAKEVVTSN 3849
Query 4119 SPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGG 4178
+LAWPL + R +KLQNNE+ P ++Q A + D NAL Y+ G
Sbjct 3850 VESLAWPLFLNCER---IIKLQNNEIIPSKIKQRPIKA-EGEGVVADGNAL--YSNEGGR 3903
Query 4179 RFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLN 4238
F+ A +SD DLK ++ G+ I ELEPPC+F+ + P GP VKYLYF++ LNNL
Sbjct 3904 TFMYAFISDKPDLKVVKWEFDGGSNAI--ELEPPCKFLVEAPSGPVVKYLYFVRNLNNLR 3961
Query 4239 RGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKML 4298
RG VLG + ATVRLQAG TE NS++L+ CAFAVD K Y D + SG +P+ NCVKML
Sbjct 3962 RGAVLGFIGATVRLQAGKQTEQATNSSLLTLCAFAVDPPKTYLDAVKSGHRPVGNCVKML 4021
Query 4299 CTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCAN 4358
+G GQAIT EA+ +Q+S+GGAS CLYCR H++HP+ GFC L+GKYVQ+P
Sbjct 4022 ANGSGNGQAITNGVEASTNQDSYGGASVCLYCRAHVEHPDMDGFCKLRGKYVQVPLGTL- 4080
Query 4359 DPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCG 4405
DP+ F L+NTVC VCG W+ GC+CD+ ++QS D+ +LN CG
Sbjct 4081 DPIRFVLENTVCKVCGCWQANGCTCDR---AVIQSVDS-GYLNE-CG 4122
Score = 75.5 bits (184), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 65/204 (32%), Positives = 94/204 (46%), Gaps = 16/204 (8%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLH 1116
VVNAAN L HGGG+A AL+ T +QV S+ Y++ NG +KVG ++ L+
Sbjct 1323 VVNAANEQLSHGGGIAKALDDLTKGELQVLSNQYVSRNGSIKVGSGVLIKCKE--HSILN 1380
Query 1117 VVGPNVNKGEDIQLLKSAYE-NFNQHEVLLAPLLSAGIFGADPIHSLR---VCVDTVRTN 1172
VVGP K +LL AY F Q V L PLLS GIF SL CV
Sbjct 1381 VVGPRKGK-HAAELLTKAYTFVFKQKGVPLMPLLSVGIFKVPITESLAAFLACVGDRVCK 1439
Query 1173 VYLAVFDKNL-YDKLVSSFLEMKSEKQVE-----QKIAEIPKEEVKPFITESKPSVEQRK 1226
+ + L V+SF ++E+ VE Q++ + E+ P + P R
Sbjct 1440 CFCYTDKERLAIQNFVTSF---QTEQPVEPLPVIQEVKGVQLEKPVPDVKVENPCEPFRI 1496
Query 1227 QDDKKIKACVEEVTTTLEETKFLT 1250
+ D K + +L+ T+ ++
Sbjct 1497 EGDAKFYDLTPSMVQSLQVTRLVS 1520
Score = 62.0 bits (149), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 52/196 (27%), Positives = 83/196 (42%), Gaps = 12/196 (6%)
Query 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
+L E + ++V T D + HT + S TYGQQ G ++ VT +KP + + + V
Sbjct 1634 TLFEAKPVQVVVTQDQRSFHTVELSTSQTYGQQLGDCVVEDKKVTNLKPVSKDKVVS--V 1691
Query 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTK-KWKYPQVNGLTSIKWADNNCYLATA 1679
+PN V+ ++Y D L+HT + VNG ++ +DNNC++
Sbjct 1692 VPN-----VDWDKHYGFVDAGIF----HTLDHTMFVFDNNVVNGKRVLRTSDNNCWINAV 1742
Query 1680 LLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHA 1739
L LQ KF P LQ + G+ A F + GE D T++ + +
Sbjct 1743 CLQLQFANAKFKPKGLQQLWESYCTGDVAMFVHWLYWITGVEKGEPSDAENTLNIISRFL 1802
Query 1740 NLDSCKRVLNVVCKTC 1755
+L TC
Sbjct 1803 KPQGSVEMLRATSTTC 1818
>sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus
NL63 OX=277944 GN=1a PE=1 SV=1
Length=4060
Score = 1189 bits (3077), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 771/2184 (35%), Positives = 1161/2184 (53%), Gaps = 174/2184 (8%)
Query 2263 CTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISS-FKWDLTAF 2321
C GY ST YC S+ C +CL + + I L F
Sbjct 1999 CGDIVSGYEKST-FNKDIYCGNSMVCKMCLFSYQEFNDLDHTSLVWKHIRDPILISLQPF 2057
Query 2322 GLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMV 2381
++ + ++ RF + +A + F S+ H W + P +
Sbjct 2058 VILVILLIFGNMYLRFGLLYFVAQFISTFGSFLGFH--QKQWFL-------HFVPFDVLC 2108
Query 2382 RMYIFFASFYYVWKSYV---HVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYA 2438
F A+F V K + H++ GCN++ C+ C K R RV TI+NG+ +SFYV A
Sbjct 2109 NE--FLATFI-VCKIVLFVRHIIVGCNNADCVACSKSARLKRVPLQTIINGMHKSFYVNA 2165
Query 2439 NGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKN 2498
NGG FC HN+ CVNCD+F G+TFI+ ++AR+L K + PT + I+D V N
Sbjct 2166 NGGTCFCNKHNFFCVNCDSFGPGNTFINGDIARELGNVVKTAVQPTAPAYVIIDKVDFVN 2225
Query 2499 GSIHLY---------FDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKC 2549
G LY FD K + L + L+N N GS N+
Sbjct 2226 GFYRLYSGDTFWRYDFDITESKYSCKEVLKNCNVLENFIVYNNSGS---NI--------- 2273
Query 2550 EESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKL 2609
+ K+A VY+SQL+C+PI L++ L+S + S + + AYV+ ++F
Sbjct 2274 --TQIKNACVYFSQLLCEPIKLVNSELLSTL--SVDFNGVLHKAYVDVLCNSF------- 2322
Query 2610 KTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDS 2669
EL N+S+ +T G SD D V + +H+ D+ ++ S
Sbjct 2323 -------FKELTANMSMAECKATL------GLTVSD---DDFVSAVANAHRYDVLLSDLS 2366
Query 2670 CNNYMLTYNKVEN-MTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQ 2728
NN+ ++Y K E+ ++ D+ C+ ++ +N V +I ++W VKDF +LS++ +K
Sbjct 2367 FNNFFISYAKPEDKLSVYDIACCMRAGSKVVNHNVLIKESIPIVWGVKDFNTLSQEGKKY 2426
Query 2729 IRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGG---KIVNNWLKQLIKVTLVFLFVAA 2785
+ K L F LT + + V T I K G K N+L V LFV A
Sbjct 2427 LVKTTKAKGLTFLLTFNDNQAITQVPATSIVAKQGAGFKRTYNFL------WYVCLFVVA 2480
Query 2786 IFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSY 2845
+F ++ + + T F +K I+ G + + C N +F+ W + G
Sbjct 2481 LFIGVSFIDYTTTVTSFHG--YDFKYIENGQLKVFEAPLHCVRNVFDNFNQWHEAKFGVV 2538
Query 2846 T-NDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGN--ICYTPSKL 2902
T N CP++ V R VVPG+P + G L F + +A GN +CY
Sbjct 2539 TTNSDKCPIVVGVSERIN--VVPGVPTNVYLV--GKTLVFTLQ--AAFGNTGVCY----- 2587
Query 2903 IEYTDFATS-ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSI 2961
++ TS C+ + CT + G V YCY+T+++EGS Y +L+P+ Y +
Sbjct 2588 -DFDGVTTSDKCIFNSACTRLEGLGGDNV-YCYNTDLIEGSKPYSTLQPNAYYKYDAKNY 2645
Query 2962 IQFPNTYLEG-SVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCG 3020
++FP G +R + T + YCR G C S GVC +W +N+ R G CG
Sbjct 2646 VRFPEILARGFGLRTIRTLATRYCRVGECRDSHKGVCFGFD-KWYVNDG--RVDDGYICG 2702
Query 3021 VDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAF 3080
++LL N+ + + +S ++ + A +T L + +F+R FG+ S+ V
Sbjct 2703 DGLIDLLVNVLSIFSSSFSVVAMSGHMLFNFLFAAFITFLCFLVTKFKRVFGDLSYGV-- 2760
Query 3081 NTLLFLMSFTVLCLTPVYS---------FLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVM 3131
FTV+C T + + F +Y++ LY F T +++ HI ++V
Sbjct 2761 --------FTVVCATLINNISYVVTQNLFFMLLYAI--LYFVFTRTVRYAWIWHIAYIVA 2810
Query 3132 FTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFNGVSF-STFEEAALCTFLLNK 3187
+ L+P+W+ + S F N K ++ +F G F TFE AA TF+L+
Sbjct 2811 YFLLIPWWLLTWF----SFAAFLELLPNVFKLKISTQLFEGDKFIGTFESAAAGTFVLDM 2866
Query 3188 EMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSD 3247
Y +L + + + Y A YNKYKY+SG+ YR A HLAKA+ D++ +D
Sbjct 2867 RSYERLINTI--SPEKLKNYAASYNKYKYYSGSASEADYRCACYAHLAKAMLDYAKDHND 2924
Query 3248 VLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVIC 3307
+LY PP S S LQSG +KMA PSG VE C+V+V G+T LNG+WL D V CPRHVI
Sbjct 2925 MLYSPPTISYNST-LQSGLKKMAQPSGCVERCVVRVCYGSTVLNGVWLGDTVTCPRHVIA 2983
Query 3308 TSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFV 3367
S +L +Y+ HNF V V L V+G +M VL++KV +N TPK+ F
Sbjct 2984 PSTTVL-IDYDHAYSTMRLHNFSVSHNGVFLGVVGVTMHGSVLRIKVSQSNVHTPKHVFK 3042
Query 3368 RIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYD-CVSFCYMH 3426
++PG +F++LACY G SGV+ +R NFTIKGSF+NG+CGS G+N+ D V FCY+H
Sbjct 3043 TLKPGDSFNILACYEGIASGVFGVNLRTNFTIKGSFINGACGSPGYNVRNDGTVEFCYLH 3102
Query 3427 HMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRF 3486
+EL +G H G+D G+ YG F D+ + Q + ++ NV+A+LYAA++NG RW+L
Sbjct 3103 QIELGSGAHVGSDFTGSVYGNFDDQPSLQVESANLMLSDNVVAFLYAALLNGCRWWLCST 3162
Query 3487 TTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILG 3546
++ FN AM Y ++ V+ L+A+TG++V + AS++ L G G+ ILG
Sbjct 3163 RVNVDGFNEWAMANGYTSVSS--VECYSILAAKTGVSVEQLLASIQHL-HEGFGGKNILG 3219
Query 3547 SALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFL 3606
+ L DEFT +VV+Q GV QS + I G L ++ ++ W+ F +
Sbjct 3220 YSSLCDEFTLAEVVKQMYGVNLQSG--KVIFGLKTMFLFSVFFTMF-------WAELF-I 3269
Query 3607 YENA-------FLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASW 3659
Y N P ++ +S MF+KHK FL +FLLP++ A +N V +
Sbjct 3270 YTNTIWINPVILTPIFCLLLFLSLVLTMFLKHKFLFLQVFLLPTVIATALYNCVL--DYY 3327
Query 3660 VMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVY 3719
+++ + + S+ ++ V + ++ L T R + + +++ + Y
Sbjct 3328 IVKFLADHFNYNVSVLQMDVQGLVNVLVCLFVVFLHTWRFSKERFTHWFTYVCSLIAVAY 3387
Query 3720 KVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCI 3779
+Y + M+ IS + Y G + V L+R IVF E +F + G+ ++
Sbjct 3388 TYFYSGDFLSLLVMFLCAIS-SDWYIGAI--VFRLSRLIVFFSPE--SVFSVFGD-VKLT 3441
Query 3780 MLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFK 3839
++VY GY Y+G+ NR+F+ T+GVYD+ VS EF+YM + GL P DA
Sbjct 3442 LVVYLICGYLVCTYWGILYWFNRFFKCTMGVYDFKVSAAEFKYMVANGLHAPHGPFDALW 3501
Query 3840 LNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDIL 3899
L+ KLLG+GG CIK++TVQSK++D+KCT+VVLL L + + ++S WA CV LHN I
Sbjct 3502 LSFKLLGIGGDRCIKISTVQSKLTDLKCTNVVLLGCLSSMNIAANSSEWAYCVDLHNKIN 3561
Query 3900 LAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFAT 3959
L D +A +++LL+ LS ++ L + DN +TLQ++AS F S+PSY A+
Sbjct 3562 LCDDPEKAQSMLLALLAFFLSKHSDFGLDGLIDSYFDNSSTLQSVASSFVSMPSYIAYEN 3621
Query 3960 AQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSE 4019
A++AYE A+ANG S ++K+LK+++N+AKSEFD + ++Q+K+ +MA+QA TQMYK+ARS
Sbjct 3622 ARQAYEDAIANGSSSQLIKQLKRAMNIAKSEFDHEISVQKKINRMAEQAATQMYKEARSV 3681
Query 4020 DKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNT 4079
++++KV SAM ++LF MLR+LD ++ ++N ARDG VPL++IP T+A+KL +V PD +
Sbjct 3682 NRKSKVISAMHSLLFGMLRRLDMSSVETVLNLARDGVVPLSVIPATSASKLTIVSPDLES 3741
Query 4080 Y-KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVK 4138
Y K CDG+ YA +W + V D D + V + EI+ +N L WPLI+ R VK
Sbjct 3742 YSKIVCDGSV-HYAGVVWTLNDVKDNDGRPVHVKEITKENVETLTWPLILNCER---VVK 3797
Query 4139 LQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPK 4198
LQNNE+ P L+Q A D NAL YNT G F+ A +S+ DLK+ ++
Sbjct 3798 LQNNEIMPGKLKQKPMKAEGDGGVLGDGNAL--YNTEGGKTFMYAYISNKADLKFVKWEY 3855
Query 4199 SDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNAT 4258
G TI EL+ PCRF+ +TP GP+VKYLYF+K LN L RG VLG + AT+RLQAG T
Sbjct 3856 EGGCNTI--ELDSPCRFMVETPNGPQVKYLYFVKNLNTLRRGAVLGFIGATIRLQAGKQT 3913
Query 4259 EVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQ 4318
E+ NS +L+ CAF+VD A Y + + G +P++NC+KML G GQAIT + +AN +Q
Sbjct 3914 ELAVNSGLLTACAFSVDPATTYLEAVKHGAKPVSNCIKMLSNGAGNGQAITTSVDANTNQ 3973
Query 4319 ESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKG 4378
+S+GGAS CLYCR H+ HP+ G+C KGK VQ+P C DP+ F L+N VC VCG W G
Sbjct 3974 DSYGGASICLYCRAHVPHPSMDGYCKFKGKCVQVPIGCL-DPIRFCLENNVCNVCGCWLG 4032
Query 4379 YGCSCDQLREPMLQSADAQSFLNR 4402
+GC+CD+ +QS D S+LN
Sbjct 4033 HGCACDR---TTIQSVDI-SYLNE 4052
Score = 80.9 bits (198), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 55/144 (38%), Positives = 74/144 (51%), Gaps = 6/144 (4%)
Query 1020 VQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKAT 1079
++ EV F+ Y NV DI V VVNAAN L HGGGVA A++ T
Sbjct 1252 IEAGEVKPFAVY----KNVKFYLGDISHLVNCVSFDFVVNAANENLLHGGGVARAIDILT 1307
Query 1080 NNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFN 1139
+Q S DYI++NGPLKVG +L + +VVGP K E L+++
Sbjct 1308 EGQLQSLSKDYISSNGPLKVGAGVMLECEKF--NVFNVVGPRTGKHEHSLLVEAYNSILF 1365
Query 1140 QHEVLLAPLLSAGIFGADPIHSLR 1163
++ + L PLLS GIFG +SL+
Sbjct 1366 ENGIPLMPLLSCGIFGVRIENSLK 1389
Score = 51.6 bits (122), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 50/174 (29%), Positives = 72/174 (41%), Gaps = 16/174 (9%)
Query 1573 TVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLP-NDDTLRVEA 1631
T D IN+ VV+ S + G+Q G DG D S EG VLP N DT+ A
Sbjct 1587 TEDGINVKDVVVESSKSLGKQLGVVS-DGVD--------SFEG----VLPINTDTVLSVA 1633
Query 1632 FEYYHTTDPSFLGRYMSALNHTKKWKYPQ--VNGLTSIKWADNNCYLATALLTLQQIELK 1689
E F + A K + YP V G + DNNC++ + LQ ++
Sbjct 1634 PEVDWVAFYGFEKAALFASLDVKPYGYPNDFVGGFRVLGTTDNNCWVNATCIILQYLKPT 1693
Query 1690 FNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDS 1743
F L + + G+ F + I + G+ GD E +S L ++ DS
Sbjct 1694 FKSKGLNVLWNKFVTGDVGPFVSFIYFITMSSKGQKGDAEEALSKLSEYLISDS 1747
Score = 38.5 bits (88), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 42/176 (24%), Positives = 72/176 (41%), Gaps = 13/176 (7%)
Query 1663 GLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV 1722
G+ + +DNNC+++T L+ LQ +L + +Q + G+ + +
Sbjct 1051 GVRVLDQSDNNCWISTTLVQLQLTKLLDDSIEMQ----LFKVGKVDSIVQKCYELSHLIS 1106
Query 1723 GELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKG 1782
G LGD + +S L + +C + C CG++ G ++ + F+KG
Sbjct 1107 GSLGDSGKLLSELLKEKY--TCSITFEMSCD-CGKKFDDQVG---CLFWIMPYTKLFQKG 1160
Query 1783 VQIPCTCGKQATKYLVQQESPFVMMSAP-PAQYELKHGTFTCASEYTGNYQCGHYK 1837
C C K T LV + V + P P + C+S Y G GHY+
Sbjct 1161 E--CCICHKMQTYKLVSMKGTGVFVQDPAPIDIDAFPVKPICSSVYLGVKGSGHYQ 1214
>sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=1a PE=1 SV=1
Length=4117
Score = 1185 bits (3065), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 757/2210 (34%), Positives = 1173/2210 (53%), Gaps = 157/2210 (7%)
Query 2230 IIWFLLLS-VCLG-SLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIP 2287
+ WF +L LG +Y+ + + + +G P C GY NS+ YC S+
Sbjct 2020 LYWFKVLGKFSLGIYALYALLFMTIRFTPIGSP-VCDDVVAGYANSS-FDKNEYCN-SVI 2076
Query 2288 CSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIM 2347
C VCL G L + + + W L+ FFY+ LA
Sbjct 2077 CKVCLYGYQELSDFSHTQVV--------WQHLRDPLIGN-------VMPFFYLAFLAIFG 2121
Query 2348 QLFFSYFAVHFIS---NSWLMWL----IINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
++ ++FI NS ++L I +Q+ P + F V HV
Sbjct 2122 GVYVKAITLYFIFQYLNSLGVFLGLQQSIWFLQLVPFDVFGDEIVVFFIVTRVLMFIKHV 2181
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GC+ ++C+ C K R RV TI G +SFYV+ANGG FCK HN+ C+NCD++
Sbjct 2182 CLGCDKASCVACSKSARLKRVPVQTIFQGTSKSFYVHANGGSKFCKKHNFFCLNCDSYGP 2241
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G TFI+D +A ++ K + PT ++ ++D V NG +LY K + S
Sbjct 2242 GCTFINDVIATEVGNVVKLNVQPTGPATILIDKVEFSNGFYYLYSGDTFWKYNFDITDSK 2301
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
+ + L+ S+ + IVF+ + K+A VY+SQ++C+P+ L+D AL++ +
Sbjct 2302 YTCKEALK----NCSIITDFIVFNNNGS-NVNQVKNACVYFSQMLCKPVKLVDSALLASL 2356
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNV-LSTFISAARQ 2639
S + + A+V+ S++F + + + + D+V L TF +A +
Sbjct 2357 --SVDFGASLHSAFVSVLSNSFGKDLSSCNDM-----QDCKSTLGFDDVPLDTFNAAVAE 2409
Query 2640 GFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTP-RDLGACIDCSARH 2698
+H+ D+ +T S NN+ +Y K E P D+ C+ A+
Sbjct 2410 ------------------AHRYDVLLTDMSFNNFTTSYAKPEEKFPVHDIATCMRVGAKI 2451
Query 2699 INAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKI 2758
+N V +I ++W V+DF++LSE+ RK I K + F LT R + T I
Sbjct 2452 VNHNVLVKDSIPVVWLVRDFIALSEETRKYIIRTTKVKGITFMLTFNDCRMHTTIPTVCI 2511
Query 2759 ALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIG-----YKAID 2813
A K G + ++ K + LF+ A F+ ++ DFS+++ +K I+
Sbjct 2512 ANKKGAGLPSFSKVKKFFWFLCLFIVAAFFALS-------FLDFSTQVSSDSDYDFKYIE 2564
Query 2814 GGVTRDIASTDTCFANKHADFDTWFSQRGG-SYTNDKACPLIAAVITREVGFVVPGLPGT 2872
G + + +C N +FD W + G + N+ +CP++ V + VPG+P
Sbjct 2565 SGQLKTFDNPLSCVHNVFINFDQWHDAKFGFTPVNNPSCPIVVGV--SDEARTVPGIPAG 2622
Query 2873 ILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPY 2932
+ G L F +C+ S + + AC+ + CT G V Y
Sbjct 2623 VYLA--GKTLVFAINTIFGTSGLCFDASGVAD-----KGACIFNSACTTLSGLGGTAV-Y 2674
Query 2933 CYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCER 2991
CY ++EG+ Y L P + Y ++DG+ + P G +R + T YCR G C +
Sbjct 2675 CYKNGLVEGAKLYSELAPHSYYKMVDGNAVSLPEIISRGFGIRTIRTKAMTYCRVGQCVQ 2734
Query 2992 SEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGG 3051
S GVC +V N + S CG LL N+ + + + +S I+
Sbjct 2735 SAEGVCFGADRFFVYNAE---SGSDFVCGTGLFTLLMNVISVFSKTVPVTVLSGQILFNC 2791
Query 3052 IVAIVVTCLAYYFMRFRRAFGEYS---HVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVI 3108
I+A V + + F +F+R FG+ S V TLL +S+ V T + +
Sbjct 2792 IIAFVAVAVCFLFTKFKRMFGDMSVGVFTVGACTLLNNVSYIVTQNT--------LGMLG 2843
Query 3109 YLYLTFYLTNDVSFLA--HIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV- 3165
Y L F T V ++ H+ +++ + + P+W+ + Y + + F N K +V
Sbjct 2844 YATLYFLCTKGVRYMWIWHLGFLISYILIAPWWVLMVY----AFSAIFEFMPNLFKLKVS 2899
Query 3166 --VFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMD 3222
+F G F +FE AA TF+L+ Y +L + + + +Y + YNKYKY+SG+
Sbjct 2900 TQLFEGDKFVGSFENAAAGTFVLDMHAYERLANSI--STEKLRQYASTYNKYKYYSGSAS 2957
Query 3223 TTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQ 3282
YR A HLAKA+ D++++ +D LY PP S S LQ+G RKMA PSG VE C+V+
Sbjct 2958 EADYRLACFAHLAKAMMDYASNHNDTLYTPPTVSYNST-LQAGLRKMAQPSGVVEKCIVR 3016
Query 3283 VTCGTTTLNGLWLDDVVYCPRHVICTSE-DMLNPNYEDLLIRKSNHNFLVQAGNVQLRVI 3341
V G LNGLWL D+V CPRHVI +S ++ +Y ++R HNF + +GNV L V+
Sbjct 3017 VCYGNMALNGLWLGDIVMCPRHVIASSTTSTIDYDYALSVLRL--HNFSISSGNVFLGVV 3074
Query 3342 GHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKG 3401
+M+ +L++KV+ N TPKY + ++PG++F++LACY+G+ +GVY MR N+TI+G
Sbjct 3075 SATMRGALLQIKVNQNNVHTPKYTYRTVRPGESFNILACYDGAAAGVYGVNMRSNYTIRG 3134
Query 3402 SFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDT 3461
SF+NG+CGS G+NI+ V FCY+H +EL +G H G+DL+G YG + D+ T Q G +
Sbjct 3135 SFINGACGSPGYNINNGTVEFCYLHQLELGSGCHVGSDLDGVMYGGYEDQPTLQVEGASS 3194
Query 3462 TITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTG 3521
T NVLA+LYAA+ING W+L+ ++ FN A+ T + D L+A+TG
Sbjct 3195 LFTENVLAFLYAALINGSTWWLSSSRIAVDRFNEWAVHNGMT--TVGNTDCFSILAAKTG 3252
Query 3522 IAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSA-VKRTIKGTH 3580
+ V + AS++ L +N G+ ILG L DEFT +VVRQ GV Q V R +
Sbjct 3253 VDVQRLLASIQSLHKN-FGGKQILGHTSLTDEFTTGEVVRQMYGVNLQGGYVSRACRN-- 3309
Query 3581 HWLLLTILTSLLVLVQS--TQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCL 3638
+ ++ S L S ++ FF++ P + +S+ M +KHK F +
Sbjct 3310 ----VLLVGSFLTFFWSELVSYTKFFWVNPGYVTPMFACLSLLSSLLMFTLKHKTLFFQV 3365
Query 3639 FLLPSLATVAYFNMVYMPASWVMRIMTWL-DMVD--TSLSGFKLKDCVMYASAVVLLILM 3695
FL+P+L + N+ + + + +L + D SL GF + V V+ IL
Sbjct 3366 FLIPALIVTSCINLAFD-----VEVYNYLAEHFDYHVSLMGFNAQGLVNIFVCFVVTILH 3420
Query 3696 TART--VYDDGARRVWTLMNVLTLVYKVYYG-NALDQAISMWALIISVTSNYSGVVTTVM 3752
T ++ A V ++ +LT Y +Y + L A++++A SVT N+ V V
Sbjct 3421 GTYTWRFFNTPASSVTYVVALLTAAYNYFYASDILSCAMTLFA---SVTGNW--FVGAVC 3475
Query 3753 FLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYD 3812
+ + V+M + + P F ++ +M Y LGYF C++G+ NR+F++++GVYD
Sbjct 3476 Y--KVAVYMALRF-PTFVAIFGDIKSVMFCYLVLGYFTCCFYGILYWFNRFFKVSVGVYD 3532
Query 3813 YLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVL 3872
Y VS EF+YM + GL P ++D+ L+ KL+G+GG+ IK+++VQSK++D+KC++VVL
Sbjct 3533 YTVSAAEFKYMVANGLRAPTGTLDSLLLSAKLIGIGGERNIKISSVQSKLTDIKCSNVVL 3592
Query 3873 LSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCE 3932
L L + V ++S WA CV LHN I L D +A E +++LL+ LS A ++ L E
Sbjct 3593 LGCLSSMNVSANSTEWAYCVDLHNKINLCNDPEKAQEMLLALLAFFLSKNSAFGLDDLLE 3652
Query 3933 EMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFD 3992
++ + LQ++AS + LPSY + A++ YE AV NG ++K+L+ ++NVAKSEFD
Sbjct 3653 SYFNDNSMLQSVASTYVGLPSYVIYENARQQYEDAVNNGSPPQLVKQLRHAMNVAKSEFD 3712
Query 3993 RDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNA 4052
R+A+ QRKL++MA+QA QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I+N A
Sbjct 3713 REASTQRKLDRMAEQAAAQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNLA 3772
Query 4053 RDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLS 4112
+DG VPL++IP +A KL +V D ++Y YA +W I + D D K+V +
Sbjct 3773 KDGVVPLSVIPAVSATKLNIVTSDIDSYNRIQREGCVHYAGTIWNIIDIKDNDGKVVHVK 3832
Query 4113 EISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYY 4172
E++ N+ +L+WPL++ R VKLQNNE+ P L+Q S A A Y
Sbjct 3833 EVTAQNAESLSWPLVLGCER---IVKLQNNEIIPGKLKQRSIKAEGDGIV---GEGKALY 3886
Query 4173 NTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIK 4232
N G F+ A +SD DL+ ++ G TI ELEPP +F+ D+P G ++KYLYF++
Sbjct 3887 NNEGGRTFMYAFISDKPDLRVVKWEFDGGCNTI--ELEPPRKFLVDSPNGAQIKYLYFVR 3944
Query 4233 GLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPIT 4292
LN L RG VLG + ATVRLQAG TE NS++L+ CAFAVD AK Y D + SG +P+
Sbjct 3945 NLNTLRRGAVLGYIGATVRLQAGKQTEQAINSSLLTLCAFAVDPAKTYIDAVKSGHKPVG 4004
Query 4293 NCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQI 4352
NCVKML +G GQA+T EA+ +Q+S+GGAS CLYCR H++HP+ GFC LKGKYVQ+
Sbjct 4005 NCVKMLANGSGNGQAVTNGVEASTNQDSYGGASVCLYCRAHVEHPSMDGFCRLKGKYVQV 4064
Query 4353 PTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNR 4402
P DP+ F L+N VC VCG W GC+CD+ ++QS D ++LN
Sbjct 4065 PLGTV-DPIRFVLENDVCKVCGCWLSNGCTCDR---SIMQSTD-MAYLNE 4109
Score = 70.9 bits (172), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 58/173 (34%), Positives = 76/173 (44%), Gaps = 10/173 (6%)
Query 993 GSEDNQTTTIQTIVEVQPQLEMELTPVVQTIE---VNSFSGYLKLTDNVYIKNADIVEEA 1049
G + T+ TI L P V ++ V F Y NV D +
Sbjct 1255 GRHQIKYDTLNTICVKDVNWTAPLVPAVDSVVEPVVKPFYSY----KNVDFYQGDF-SDL 1309
Query 1050 KKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHN 1109
K+ VVNAAN L HGGG+A A++ T +Q S+DYI +GP+KVG +L
Sbjct 1310 VKLPCDFVVNAANEKLSHGGGIAKAIDVYTKGMLQKCSNDYIKAHGPIKVGRGVMLEA-- 1367
Query 1110 LAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSL 1162
L +VVGP K L+K+ F V L PL+S GIF SL
Sbjct 1368 LGLKVFNVVGPRKGKHAPELLVKAYKSVFANSGVALTPLISVGIFSVPLEESL 1420
Score = 49.3 bits (116), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 84/339 (25%), Positives = 136/339 (40%), Gaps = 28/339 (8%)
Query 1548 GEVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKI 1607
G V T D+++ + + V IKV T D ++ V+ + TYGQQ GP ++ VT
Sbjct 1616 GFVSTPDDVERFYANKSV-VIKV--TEDTRSVKAVKVESTATYGQQIGPCLVNDTVVTDN 1672
Query 1608 KPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQ--VNGLT 1665
KP + V+PN + ++ ++ D + G + L+HT + +P VNG
Sbjct 1673 KPVVADVVAK--VVPNAN------WDSHYGFDKA--GEF-HMLDHTG-FTFPSEVVNGRR 1720
Query 1666 SIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGEL 1725
IK DNNC++ L LQ +F LQ + G+ A F + G+
Sbjct 1721 VIKTTDNNCWVNVTCLQLQFARFRFKSAGLQAMWESYCTGDVAMFVHWLYWLTGVDKGQP 1780
Query 1726 GDVRETMSYLFQH---ANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKG 1782
D ++ L ++ A + +RV + C C ++ T V A + + G
Sbjct 1781 SDSENALNMLSKYIVPAGSVTIERVTHDGC-CCSKRVVTAPVVNASVLKLGVEDGLCPHG 1839
Query 1783 VQ-IPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITS 1841
+ I + T +V P V P+ LK ++T + GN GHY +
Sbjct 1840 LNYIGKVVVVKGTTIVVNVGKPVV----APSHLFLKGVSYTTFLD-NGNGVVGHYT-VFD 1893
Query 1842 KETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPV 1880
T DG P+T+V E + PV
Sbjct 1894 HGTGMVHDGDAFVPGDLNVSPVTNVVVSEQTAVVIKDPV 1932
>sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus
229E OX=11137 GN=1a PE=1 SV=1
Length=4085
Score = 1181 bits (3054), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 773/2280 (34%), Positives = 1201/2280 (53%), Gaps = 187/2280 (8%)
Query 2172 FFTLLLQLCTFTRST----NSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLI 2227
FFT LL + T ++ + +I A P +S+ K+ L+AS LKS
Sbjct 1936 FFTWLLSMFTLCKTAVTTGDVKIMAKAPQRTGVVLKRSL-KYNLKASAAVLKSK------ 1988
Query 2228 NIIIWFLLLSVC-LGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSI 2286
W+LL L LIY+ ++ +L G ++C+ GY S N YC GS+
Sbjct 1989 ----WWLLAKFTKLLLLIYTLYSVVLLCVRFGPFNFCSETVNGYAKS-NFVKDDYCDGSL 2043
Query 2287 PCSVCLSGLDSLDTYPSLETI--QITISSFKWDLTAFGLVAEWFL---AYILFTRFFYVL 2341
C +CL G L + L+ + IT F ++ F ++ + Y+ ++V
Sbjct 2044 GCKMCLFGYQELSQFSHLDVVWKHITDPLFS-NMQPFIVMVLLLIFGDNYLRCFLLYFVA 2102
Query 2342 GLAAIMQLFFSY----FAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY 2397
+ + + +F Y + +HFI + ++ V + + + VR
Sbjct 2103 QMISTVGVFLGYKETNWFLHFIPFDVICDELLVTVIVIKVISFVR--------------- 2147
Query 2398 VHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDT 2457
HV+ GC + C+ C K R R TIVNGV+RSFYV ANGG FCK H + CV+CD+
Sbjct 2148 -HVLFGCENPDCIACSKSARLKRFPVNTIVNGVQRSFYVNANGGSKFCKKHRFFCVDCDS 2206
Query 2458 FCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLY---------FDKA 2508
+ GSTFI+ EV+R+L K + PT + ++D V +NG LY FD
Sbjct 2207 YGYGSTFITPEVSRELGNITKTNVQPTGPAYVMIDKVEFENGFYRLYSCETFWRYNFDIT 2266
Query 2509 GQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQP 2568
K + + LD+ N G+ NV + K+ASVY+SQL+C+P
Sbjct 2267 ESKYSCKEVFKNCNVLDDFIVFNNNGT---NV-----------TQVKNASVYFSQLLCRP 2312
Query 2569 ILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSL-D 2627
I L+D L+S + S + + AY++ ++F + L ++ AE + A +S+ D
Sbjct 2313 IKLVDSELLSTL--SVDFNGVLHKAYIDVLRNSFG---KDLNANMSLAECKRALGLSISD 2367
Query 2628 NVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNK-VENMTPR 2686
+ ++ IS A H+ D+ ++ S NN++ +Y K E ++
Sbjct 2368 HEFTSAISNA---------------------HRCDVLLSDLSFNNFVSSYAKPEEKLSAY 2406
Query 2687 DLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCAT 2746
DL C+ A+ +NA V ++W+ KDF SLS + RK I +K L F LT
Sbjct 2407 DLACCMRAGAKVVNANVLTKDQTPIVWHAKDFNSLSAEGRKYIVKTSKAKGLTFLLTINE 2466
Query 2747 TRQVVNVVTTKIALKGGKIVNN----WLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDF 2802
+ V + T I K G WL L + + F F ++S
Sbjct 2467 NQAVTQIPATSIVAKQGAGDAGHSLTWLWLLCGLVCLIQFYLCFFMPYFMYDIVS----- 2521
Query 2803 SSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTW-FSQRGGSYTNDKACPLIAAVITRE 2861
S E +K I+ G ++ + C N +F+ W +++ G + N ++CP++ V E
Sbjct 2522 SFEGYDFKYIENGQLKNFEAPLKCVRNVFENFEDWHYAKFGFTPLNKQSCPIVVGV--SE 2579
Query 2862 VGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICY------TPSKLIEYTDFATSACVL 2915
+ V G+P + G L F + +CY TP K C+
Sbjct 2580 IVNTVAGIPSNVYLV--GKTLIFTLQAAFGNAGVCYDIFGVTTPEK-----------CIF 2626
Query 2916 AAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEG-SVR 2974
+ CT + G V YCY+T ++EGS+ Y S++ + Y +G+ I+ P +G R
Sbjct 2627 TSACTRLEGLGGNNV-YCYNTALMEGSLPYSSIQANAYYKYDNGNFIKLPEVIAQGFGFR 2685
Query 2975 VVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPL 3034
V T ++YCR G C S AGVC +W +N+ R G CG NL+ N+ +
Sbjct 2686 TVRTIATKYCRVGECVESNAGVCFGFD-KWFVNDG--RVANGYVCGTGLWNLVFNILSMF 2742
Query 3035 IQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCL 3094
+S I+ + + +FRR FG+ S V + L++ +
Sbjct 2743 SSSFSVAAMSGQILLNCALGAFAIFCCFLVTKFRRMFGDLSVGVCTVVVAVLLNNVSYIV 2802
Query 3095 TPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFY 3154
T + Y+++Y + T L +++ +++ + P+W+ Y + + T
Sbjct 2803 TQNLVTMIA-YAILYFFATRSLR--YAWIWCAAYLIAYISFAPWWLCAWYFLAMLTG--- 2856
Query 3155 WFFSNYLKRRV---VFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
+ LK +V +F G F TFE AA TF+++ Y KL + + + Y A
Sbjct 2857 -LLPSLLKLKVSTNLFEGDKFVGTFESAAAGTFVIDMRSYEKLANSI--SPEKLKSYAAS 2913
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMA 3270
YN+YKY+SG + YR A +LAKA+ DFS +D+LY PP S S LQ+G RKMA
Sbjct 2914 YNRYKYYSGNANEADYRCACYAYLAKAMLDFSRDHNDILYTPPTVSYGST-LQAGLRKMA 2972
Query 3271 FPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLIRKSNHNF 3329
PSG VE C+V+V G T LNGLWL D+VYCPRHVI + + ++ ++E ++R HNF
Sbjct 2973 QPSGFVEKCVVRVCYGNTVLNGLWLGDIVYCPRHVIASNTTSAIDYDHEYSIMRL--HNF 3030
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G L V+G +M LK+KV N TP++ F ++ G+ F++LACY+G GV+
Sbjct 3031 SIISGTAFLGVVGATMHGVTLKIKVSQTNMHTPRHSFRTLKSGEGFNILACYDGCAQGVF 3090
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR N+TI+GSF+NG+CGS G+N+ V F YMH +EL +G H G+ +G YG F
Sbjct 3091 GVNMRTNWTIRGSFINGACGSPGYNLKNGEVEFVYMHQIELGSGSHVGSSFDGVMYGGFE 3150
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D+ Q + +TVNV+A+LYAA++NG W+L + +N A + + +
Sbjct 3151 DQPNLQVESANQMLTVNVVAFLYAAILNGCTWWLKGEKLFVEHYNEWAQANGFTAMNGE- 3209
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
D L+A+TG+ V + ++ ++L NG G+ ILG + L DEF+ +VV+Q GV Q
Sbjct 3210 -DAFSILAAKTGVCVERLLHAI-QVLNNGFGGKQILGYSSLNDEFSINEVVKQMFGVNLQ 3267
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYEN-AFL-PFAMGIIAMSAFAMM 3627
S K T + +++ V+ + + ++ N FL PF + ++A+S
Sbjct 3268 SG-----KTTSMFKSISLFAGFFVMFWAELFVYTTTIWVNPGFLTPFMILLVALSLCLTF 3322
Query 3628 FVKHKHAFLCLFLLPSLATVAYFNMVYMPASW---VMRIMTWLDMVDTSLSGFKLKDCVM 3684
VKHK FL +FLLPS+ A N +W V +++ + S+ ++ V
Sbjct 3323 VVKHKVLFLQVFLLPSIIVAAIQN-----CAWDYHVTKVLAEKFDYNVSVMQMDIQGFVN 3377
Query 3685 YASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNY 3744
+ + +L T R + L +++ ++Y Y +S+ +++ SN
Sbjct 3378 IFICLFVALLHTWRFAKERCTHWCTYLFSLIAVLYTALYSY---DYVSLLVMLLCAISNE 3434
Query 3745 SGVVTTVMFLAR-GIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
+ + + R G+ F+ VEY F + ++ ++L Y LG+ Y+GL +NR+
Sbjct 3435 WYIGAIIFRICRFGVAFLPVEYVSYF----DGVKTVLLFYMLLGFVSCMYYGLLYWINRF 3490
Query 3804 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMS 3863
+ TLGVYD+ VS EF+YM + GL P DA L+ KL+G+GG IKV+TVQSK++
Sbjct 3491 CKCTLGVYDFCVSPAEFKYMVANGLNAPNGPFDALFLSFKLMGIGGPRTIKVSTVQSKLT 3550
Query 3864 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3923
D+KCT+VVL+ +L + + S+SK WA CV++HN I L D A E +++LL+ LS
Sbjct 3551 DLKCTNVVLMGILSNMNIASNSKEWAYCVEMHNKINLCDDPETAQELLLALLAFFLSKHS 3610
Query 3924 AVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKS 3983
+ L + +N + LQ++AS F +PS+ A+ TA++ YE AVANG S ++K+LKK+
Sbjct 3611 DFGLGDLVDSYFENDSILQSVASSFVGMPSFVAYETARQEYENAVANGSSPQIIKQLKKA 3670
Query 3984 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4043
+NVAK+EFDR++++Q+K+ +MA+QA MYK+AR+ ++++KV SAM ++LF MLR+LD
Sbjct 3671 MNVAKAEFDRESSVQKKINRMAEQAAAAMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMS 3730
Query 4044 ALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY-KNTCDGTTFTYASALWEIQQVV 4102
+++ I+N AR+G VPL++IP T+AA+L+VV+PD++++ K DG YA +W +Q+V
Sbjct 3731 SVDTILNMARNGVVPLSVIPATSAARLVVVVPDHDSFVKMMVDGFVH-YAGVVWTLQEVK 3789
Query 4103 DADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4162
D D K V L +++ +N L WPLI+T R VKLQNNE+ P ++ +
Sbjct 3790 DNDGKNVHLKDVTKENQEILVWPLILTCER---VVKLQNNEIMPGKMKVKATKGEGDGGI 3846
Query 4163 CTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4222
++ NAL YN G F+ A ++ +K+ ++ G T+ ELEPPCRFV DTP G
Sbjct 3847 TSEGNAL--YNNEGGRAFMYAYVTTKPGMKYVKWEHDSGVVTV--ELEPPCRFVIDTPTG 3902
Query 4223 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKD 4282
P++KYLYF+K LNNL RG VLG + ATVRLQAG TE +NS +L+ C+FAVD A AY D
Sbjct 3903 PQIKYLYFVKNLNNLRRGAVLGYIGATVRLQAGKQTEFVSNSHLLTHCSFAVDPAAAYLD 3962
Query 4283 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4342
+ G +P+ NCVKML +G+GQAIT T ++N Q+++GGAS C+YCR H+ HP GF
Sbjct 3963 AVKQGAKPVGNCVKMLTNGSGSGQAITCTIDSNTTQDTYGGASVCIYCRAHVAHPTMDGF 4022
Query 4343 CDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNR 4402
C KGK+VQ+P NDP+ F L+NTVC VCG W +GC+CD+ +QS D S+LN
Sbjct 4023 CQYKGKWVQVPIG-TNDPIRFCLENTVCKVCGCWLNHGCTCDR---TAIQSFD-NSYLNE 4077
Score = 75.9 bits (185), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 71/245 (29%), Positives = 110/245 (45%), Gaps = 16/245 (7%)
Query 991 QDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYL---KLT-----DNVYIKN 1042
Q + D T + ++E+ +TP+ T++ ++ KL DNV
Sbjct 1226 QPWTNDALNTICIKDADYNAKVEISVTPIKNTVDTTPKEEFVVKEKLNAFLVHDNVAFYQ 1285
Query 1043 ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGS 1102
D+ V +VNAAN L HGGG+A AL+ T +Q S ++I G +KVG
Sbjct 1286 GDVDTVVNGVDFDFIVNAANENLAHGGGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTG 1345
Query 1103 CVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSL 1162
++ +L +VVGP K E L+K+ N+ L P+LS GIFG SL
Sbjct 1346 VMVECDSL--RIFNVVGPRKGKHERDLLIKAYNTINNEQGTPLTPILSCGIFGIKLETSL 1403
Query 1163 RVCVDTVRTN-VYLAVFDKNLYDKL---VSSFLEMKSEKQ--VEQKIAEIPKEEVKPFIT 1216
V +D T V + V+ K+ VS + ++ +Q +E K + K KP+
Sbjct 1404 EVLLDVCNTKEVKVFVYTDTEVCKVKDFVSGLVNVQKVEQPKIEPKPVSVIKVAPKPYRV 1463
Query 1217 ESKPS 1221
+ K S
Sbjct 1464 DGKFS 1468
Score = 56.2 bits (134), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 74/339 (22%), Positives = 137/339 (40%), Gaps = 30/339 (9%)
Query 1560 LSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFY 1619
L E + I + T D +N+H V ++ QQ G D++ P + + +
Sbjct 1595 LKAAEAKVITIKVTEDGVNVHDVTVTTDKSFEQQVGVIADKDKDLSGAVPSDLNTSELL- 1653
Query 1620 VLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTK-KWKYPQVNGLTSIKWADNNCYLAT 1678
+ V+ E+Y D + ++H+ ++ VNG+ +K +DNNC++
Sbjct 1654 ----TKAIDVDWVEFYGFKD----AVTFATVDHSAFAYESAVVNGIRVLKTSDNNCWVNA 1705
Query 1679 ALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQH 1738
+ LQ + F L A+ + G+ F A + G+ GD +T++ L ++
Sbjct 1706 VCIALQYSKPHFISQGLDAAWNKFVLGDVEIFVAFVYYVARLMKGDKGDAEDTLTKLSKY 1765
Query 1739 -ANLDSCKRVLNVVCKTCGQQ-QTTLKGVEAVMYMGTLSYEQFKKGVQIP-CTCGKQATK 1795
AN + C C + + ++ + + + ++ + GVQ+ C G +
Sbjct 1766 LANEAQVQLEHYSSCVECDAKFKNSVASINSAIVCASVK----RDGVQVGYCVHGIKYYS 1821
Query 1796 YLVQQESPFVMMSA----PPAQYELKHGTFTCASEYTGNYQCGHYK-HITSKETLYCIDG 1850
+ +++S P AQ L G A ++G GHY + T+K+++Y DG
Sbjct 1822 RVRSVRGRAIIVSVEQLEPCAQSRLLSGVAYTA--FSGPVDKGHYTVYDTAKKSMY--DG 1877
Query 1851 ALLTKSSEYKGPITDVF----YKENSYTTTIKPVTYKLD 1885
K +T V Y T KPV +LD
Sbjct 1878 DRFVKHDLSLLSVTSVVMVGGYVAPVNTVKPKPVINQLD 1916
Score = 50.4 bits (119), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 62/267 (23%), Positives = 110/267 (41%), Gaps = 18/267 (7%)
Query 1658 YPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAY 1717
+ ++NGL +K DNNC++ + +L +Q + A+Q + R + C
Sbjct 1038 FEELNGLKILKQLDNNCWVNSVMLQIQLTGILDGDYAMQ-FFKMGRVAKMIERC-YTAEQ 1095
Query 1718 CNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYE 1777
C + G +GDV M L + +L + V++ C +C + G AV++ T + +
Sbjct 1096 CIR--GAMGDVGLCMYRLLK--DLHTGFMVMDYKC-SCTSGRLEESG--AVLFC-TPTKK 1147
Query 1778 QFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYK 1837
F G + C + T +Q FV P C+S + G CGHY+
Sbjct 1148 AFPYGTCLNCNAPRMCTIRQLQGTIIFVQQKPEPVNPVSFVVKPVCSSIFRGAVSCGHYQ 1207
Query 1838 HITSKETLYCIDGALLTKSSEYKG-PITDVFYKENSYTT----TIKPVTYKLDGVVCTE- 1891
+ L C+DG + K + + + K+ Y ++ P+ +D E
Sbjct 1208 TNIYSQNL-CVDGFGVNKIQPWTNDALNTICIKDADYNAKVEISVTPIKNTVDTTPKEEF 1266
Query 1892 -IDPKLDNYYKKDNSYFTEQPIDLVPN 1917
+ KL+ + DN F + +D V N
Sbjct 1267 VVKEKLNAFLVHDNVAFYQGDVDTVVN 1293
Score = 37.4 bits (85), Expect = 9.0, Method: Compositional matrix adjust.
Identities = 62/268 (23%), Positives = 103/268 (38%), Gaps = 29/268 (11%)
Query 662 GQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCV 721
G + TCAK K + + N FL ++ IGG K + ++ + +
Sbjct 749 GLLGTCAKRFKRWLGILLEAYNAFLDTVVSTVKIGGLTFKTYAFDKPYIVIRDIVCKVEN 808
Query 722 KSREETGLLMPLKAP-KEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
K+ E L P K E +P T D++ +E +E VE G
Sbjct 809 KTEAEWIELFPHNDRIKSFSTFESAYMPIADPTHF------DIEEVELLDAEFVEPGCGG 862
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDT-VIEVQGYKSV 839
I+ + + KD Y + N++ FT G KV+F DD V +++ V
Sbjct 863 ILAVIDEHVFYK-KDGVYYPSNGTNILPV--AFTKAAGG--KVSFSDDVEVKDIEPVYRV 917
Query 840 NITFEL-DERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLD 898
+ FE DE++ V + G D+ KT+Q + L +
Sbjct 918 KLCFEFEDEKLVDVCEKAIGKKIKHEGD---------WDSFCKTIQ------SALSVVSC 962
Query 899 EWSMATYYLFDESGEFKLASHMYCSFYP 926
++ TYY++DE G L+ + S +P
Sbjct 963 YVNLPTYYIYDEEGGNDLSLPVMISEWP 990
>sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=1a PE=1 SV=1
Length=4017
Score = 1127 bits (2916), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 727/2194 (33%), Positives = 1125/2194 (51%), Gaps = 152/2194 (7%)
Query 2263 CTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWD----L 2318
C G + Y NS+ + A C SI C CL+ D L + L+ S W+ L
Sbjct 1921 CNGAVQAYKNSSFIKSAV-CGNSILCKACLASYDELADFQHLQVTWDFKSDPLWNRLVQL 1979
Query 2319 TAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPIS 2378
+ F +A + Y+ R F + ++ + L+ SYF ++ SW + ++V IS
Sbjct 1980 SYFAFLAVFGNNYV---RCFLMYFVSQYLNLWLSYFG--YVEYSWFL----HVVNFESIS 2030
Query 2379 AMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYA 2438
A + + K H+V C++ +C C + R TR+ +VNG ++ YV+A
Sbjct 2031 AEFVIVVIVVKAVLALK---HIVFACSNPSCKTCSRTARQTRIPIQVVVNGSMKTVYVHA 2087
Query 2439 NGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKN 2498
NG FCK HN+ C NCD++ +TFI DE+ RDLS K+ + TD+S V V +
Sbjct 2088 NGTGKFCKKHNFYCKNCDSYGFENTFICDEIVRDLSNSVKQTVYATDRSHQEVTKVECSD 2147
Query 2499 GSIHLY---------FDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKC 2549
G Y +D +K + L + LD+ + GS NV
Sbjct 2148 GFYRFYVGDEFTSYDYDVKHKKYSSQEVLKSMLLLDDFIVYSPSGSALANV--------- 2198
Query 2550 EESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKL 2609
++A VY+SQL+ +PI +++ L+ D+ S + +F+A N ++FNV + +
Sbjct 2199 -----RNACVYFSQLIGKPIKIVNSDLLEDL--SVDFKGALFNAKKNVIKNSFNVDVSEC 2251
Query 2610 KTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDS 2669
K L E + +L+ STF A +H+ I +T S
Sbjct 2252 KNL-----DECYRACNLNVSFSTFEMAVNN------------------AHRFGILITDRS 2288
Query 2670 CNNYMLTYNK--VENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRK 2727
NN+ + K ++ D+G C+ A+ +NA+V +++W +DF +LS +K
Sbjct 2289 FNNFWPSKVKPGSSGVSAMDIGKCMTSDAKIVNAKVLTQRGKSVVWLSQDFAALSSTAQK 2348
Query 2728 QIRSAAKKNNLPFKLTCATTRQVVNV----VTTKIALKGGK---IVNNWLKQLIKVTLVF 2780
+ + + F LT ++ T ++ K G V LKQ++ + VF
Sbjct 2349 VLVKTFVEEGVNFSLTFNAVGSDDDLPYERFTESVSPKSGSGFFDVITQLKQIVILVFVF 2408
Query 2781 LFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQ 2840
+F+ L + V ++ S+E Y I G+ + T +C N + F WF
Sbjct 2409 IFICG---LCSVYSVATQSYIESAEGYDYMVIKNGIVQPFDDTISCVHNTYKGFGDWFKA 2465
Query 2841 RGGSY-TNDKACPLIAA-VITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYT 2898
+ G T K+CP++ V E +P +P + + G L F V N+CY
Sbjct 2466 KYGFIPTFGKSCPIVVGTVFDLENMRPIPDVPAYV--SIVGRSLVFAINAAFGVTNMCYD 2523
Query 2899 PSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMD 2958
+ D CV CT G V YC ++EG+ Y L PD Y
Sbjct 2524 HTGNAVSKDSYFDTCVFNTACTTLTGLGGTIV-YCAKQGLVEGAKLYSDLMPDYYYEHAS 2582
Query 2959 GSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVF 3018
G++++ P +R V T + YCR G C S+AG C +V +N++ G
Sbjct 2583 GNMVKLPAIIRGLGLRFVKTQATTYCRVGECIDSKAGFCFGGDNWFVYDNEFGN---GYI 2639
Query 3019 CGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVV 3078
CG + N+F + + S +++ I+A + + Y ++F++ FG+
Sbjct 2640 CGNSVLGFFKNVFKLFNSNMSVVATSGAMLVNIIIACLAIAMCYGVLKFKKIFGDC---- 2695
Query 3079 AFNTLLFLMSFTVLCLTPVYSFLPG--VYSVIYLYLTFYLTNDVSF--LAHIQWMVMFTP 3134
T L +M L + V F+ + +IY + +++T +++ + +++ +
Sbjct 2696 ---TFLIVMIIVTLVVNNVSYFVTQNTFFMIIYAIVYYFITRKLAYPGILDAGFIIAYIN 2752
Query 3135 LVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFNGVSF-STFEEAALCTFLLNKEMY 3190
+ P+++ AYI+ Y + K +V +F G F FE AA+ TF+++ Y
Sbjct 2753 MAPWYVITAYILVF----LYDSLPSLFKLKVSTNLFEGDKFVGNFESAAMGTFVIDMRSY 2808
Query 3191 LKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLY 3250
+ + + + Y +NKYKY++G+M YR A HL KAL D+S + +D+LY
Sbjct 2809 ETIVNST--SIARIKSYANSFNKYKYYTGSMGEADYRMACYAHLGKALMDYSVNRTDMLY 2866
Query 3251 QPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSE 3310
PP S+ S LQSG RKMA PSG VE C+V+V+ G LNGLWL D V CPRHVI S+
Sbjct 2867 TPPTVSVNST-LQSGLRKMAQPSGLVEPCIVRVSYGNNVLNGLWLGDEVICPRHVI-ASD 2924
Query 3311 DMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQ 3370
NYE+ + HNF V NV L V+ + L LKV+ NP TP++KF I+
Sbjct 2925 TTRVINYENEMSSVRLHNFSVSKNNVFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIK 2984
Query 3371 PGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMEL 3430
G++F++LACY G P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL
Sbjct 2985 AGESFNILACYEGCPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLEL 3044
Query 3431 PTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTL 3490
G H G++ EG YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + +L
Sbjct 3045 GNGSHVGSNFEGEMYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSL 3104
Query 3491 NDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALL 3550
+N A ++ L+ D L+A+TG +V + S+ L G GRTIL L
Sbjct 3105 ESYNTWAKTNSFTELSS--TDAFSMLAAKTGQSVEKLLDSIVRL-NKGFGGRTILSYGSL 3161
Query 3551 EDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLY--- 3607
DEFTP +V+RQ GV Q+ G I+T++ +L + L FF+Y
Sbjct 3162 CDEFTPTEVIRQMYGVNLQA-------GKVKSFFYPIMTAMTILFA---FWLEFFMYTPF 3211
Query 3608 ---ENAFLPFAMGIIAM-SAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRI 3663
F+ + + + S + +KHK F F+LPS+ V N+ + S+ +
Sbjct 3212 TWINPTFVSIVLAVTTLISTVFVSGIKHKMLFFMSFVLPSVILVTAHNL-FWDFSYYESL 3270
Query 3664 MTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYY 3723
+ ++ +T ++ ++ ++ + + R + + +L + V
Sbjct 3271 QSIVENTNTMFLPVDMQGVMLTVFCFIVFVTYSVRFFTCKQSWFSLAVTTILVIFNMVKI 3330
Query 3724 GNALDQA----------ISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
D+ ++M +I+S+T+ VV +A IV +CV P F++
Sbjct 3331 FGTSDEPWTENQIAFCFVNMLTMIVSLTTKDWMVVIASYRIAYYIV-VCV--MPSAFVSD 3387
Query 3774 -NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK 3832
++CI +VY GY CY+G+ +NR+ +T GVY + VS E +YM + L PK
Sbjct 3388 FGFMKCISIVYMACGYLFCCYYGILYWVNRFTCMTCGVYQFTVSAAELKYMTANNLSAPK 3447
Query 3833 NSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCV 3892
N+ DA L+ KL+GVGGK IK++TVQSK++++KCT+VVLL +L ++ VES+SK W CV
Sbjct 3448 NAYDAMILSAKLIGVGGKRNIKISTVQSKLTEMKCTNVVLLGLLSKMHVESNSKEWNYCV 3507
Query 3893 QLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLP 3952
LHN+I L D EK+++L++ LS D+++L E +N LQ++AS +++LP
Sbjct 3508 GLHNEINLCDDPEIVLEKLLALIAFFLSKHNTCDLSELIESYFENTTILQSVASAYAALP 3567
Query 3953 SYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQM 4012
S+ A A+ E+A N S +LK+L K+ N+AKS+F+R+A++Q+KL+KMA+QA M
Sbjct 3568 SWIALEKARADLEEAKKNDVSPQILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAAASM 3627
Query 4013 YKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMV 4072
YK+AR+ D+++K+ SAM ++LF ML+KLD ++N II+ AR+G +PL+IIP +A +L+V
Sbjct 3628 YKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATRLVV 3687
Query 4073 VIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALR 4132
+ P + YA A+W I +V DA+ V L E++ N NL WPL +T R
Sbjct 3688 ITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAANELNLTWPLSITCER 3747
Query 4133 ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLK 4192
KLQNNE+ P L++ + A T + A + G F+ A ++ +LK
Sbjct 3748 TT---KLQNNEIMPGKLKERAVRASATLDGEAFGSGKALMASESGKSFMYAFIASDNNLK 3804
Query 4193 WARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRL 4252
+ ++ ++ I ELE P RF D GP+VKYLYF+K LN L RG VLG + ATVRL
Sbjct 3805 YVKWESNN--DIIPIELEAPLRFYVDGANGPEVKYLYFVKNLNTLRRGAVLGYIGATVRL 3862
Query 4253 QAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTP 4312
QAG TE P+NS++L+ CAF+ D AKAY D + G QP+ NCVKML G G A+T
Sbjct 3863 QAGKPTEHPSNSSLLTLCAFSPDPAKAYVDAVKRGMQPVNNCVKMLSNGAGNGMAVTNGV 3922
Query 4313 EANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTV 4372
EAN Q+S+GGAS C+YCRCH++HP G C KGK+VQIPT DP+ F ++N VC V
Sbjct 3923 EANTQQDSYGGASVCIYCRCHVEHPAIDGLCRYKGKFVQIPTG-TQDPIRFCIENEVCVV 3981
Query 4373 CGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGV 4406
CG W GC CD R M QS+LN CGV
Sbjct 3982 CGCWLNNGCMCD--RTSMQSFTVDQSYLNE-CGV 4012
Score = 62.0 bits (149), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 69/288 (24%), Positives = 123/288 (43%), Gaps = 38/288 (13%)
Query 986 QTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADI 1045
+ V QQ E+N+++ + ++ P+ + + P + +++ + G L + N
Sbjct 1293 EKVEQQPIVEENKSSIEKEEIQ-SPKNDDLILPFYKAGKLSFYQGALDVLINF------- 1344
Query 1046 VEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVL 1105
++P V+VNAAN LKH GGVA A++ T + S DY+ N + G +
Sbjct 1345 ------LEPDVIVNAANGDLKHMGGVARAIDVFTGGKLTERSKDYLKKNKSIAPGNAVFF 1398
Query 1106 SGHNLAKH--CLHVVGPNVNKGEDIQLLKSAYENFNQHE-VLLAPLLSAGIFGADPIHSL 1162
N+ +H L+ VGP L + Y+ + E +L PL+S GIF
Sbjct 1399 --ENVIEHLSVLNAVGPRNGDSRVEAKLCNVYKAIAKCEGKILTPLISVGIF-------- 1448
Query 1163 RVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKI--AEIPKEEVKPFITESKP 1220
VR L K + D+ ++ F+ E+Q + IP + + +
Sbjct 1449 -----NVRLETSLQCLLKTVNDRGLNVFVYTDQERQTIENFFSCSIPVNVTEDNVNHERV 1503
Query 1221 SVEQRKQDDKKIKACV----EEVTTTLEETKFLTENLLLYIDINGNLH 1264
SV K +++K V ++VT L + + ++ IDI+ H
Sbjct 1504 SVSFDKTYGEQLKGTVVIKDKDVTNQLPSAFDVGQKVIKAIDIDWQAH 1551
Score = 50.4 bits (119), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 58/235 (25%), Positives = 95/235 (40%), Gaps = 34/235 (14%)
Query 1656 WKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALIL 1715
+K +NG +K DNNC++ LQ + FN +A+ + + G+ +F L
Sbjct 1075 FKTTNLNGKIILKQGDNNCWINACCYQLQAFDF-FN----NEAWEKFKKGDVMDFVNLCY 1129
Query 1716 AYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLS 1775
A G GD + + + + K VL C CG+++ L+ AV + L
Sbjct 1130 AATTLARGHSGDAEYLLELMLN--DYSTAKIVLAAKCG-CGEKEIVLE--RAVFKLTPLK 1184
Query 1776 YEQFKKGVQIPC----TCGKQATKY-------LVQQESPFVMMSAPPAQYELKHGTFTCA 1824
E F GV C TC + + ++ +++P M P + +
Sbjct 1185 -ESFNYGVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHAV-------- 1235
Query 1825 SEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKP 1879
YTG Q GHY + E YC+DG + K + + + +F N T KP
Sbjct 1236 --YTGTTQNGHY-MVDDIEHGYCVDG-MGIKPLKKRCYTSTLFINANVMTRAEKP 1286
Score = 41.2 bits (95), Expect = 0.54, Method: Compositional matrix adjust.
Identities = 94/402 (23%), Positives = 132/402 (33%), Gaps = 85/402 (21%)
Query 144 DLGDELGTDPYEDFQENWNTKHSSGVTREL-MRELNGGAYTRYVDNNFCGPDGYPL--EC 200
DL L T+P Q + +GV + ++ G YVD CG DG P+
Sbjct 71 DLKPVLLTEPSVMLQGFIVRANCNGVLEDFDLKIARTGRGAIYVDQYMCGADGKPVIEGD 130
Query 201 IKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLA 260
KD D I+ + Y C AW T R EK QT F I+
Sbjct 131 FKDYFGDE-----------DIIEFEGEEYHC-------AWTTVRDEKPLNQQTLFTIQEI 172
Query 261 KKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVY-----PVASPNECNQM 315
+ +N + P+ P N + + P V+K + +Y P +C
Sbjct 173 Q----YNLDIPH-KLP-NCATRHVAPPVKKNSKIVLSEDYKKLYDIFGSPFMGNGDCLSK 226
Query 316 CLSTL------MKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIY 369
C TL ++C CG S GD+ CG K G T P +AVV
Sbjct 227 CFDTLHFIAATLRCP-CGSESSGVGDWTGFKTACCGLSGKVK-GVTLGDIKPGDAVV--- 281
Query 370 CPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASA 429
T + G F CV Y G + W +
Sbjct 282 -------------------------TSMSAGKGVKFFANCVLQYAGDVEGVSIW--KVIK 314
Query 430 NIGCNHTGVVGEGSEGLNDNLLEILQKEKVNIN-----IVGDFKLNEEIAIILASFSAST 484
+ T V G EG ++ ++ K V + I GD II ST
Sbjct 315 TFTVDET-VCTPGFEGELNDFIKPESKSLVACSVKRAFITGDIDDAVHDCIITGKLDLST 373
Query 485 SAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQ 526
+ F GL +K V+ CG V AW + E+
Sbjct 374 NLFGNV--GLLFKKTPWFVQKCGALFVD-------AWKVVEE 406
Score = 37.4 bits (85), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 61/286 (21%), Positives = 107/286 (37%), Gaps = 29/286 (10%)
Query 1567 TIKVFTTVDNINLHTQVVDMSMTYGQQF-GPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+I V T DN+N V TYG+Q G + DVT P G+
Sbjct 1488 SIPVNVTEDNVNHERVSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAFDVGQKVI-----K 1542
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSI--KWADNNCYLATALLTL 1683
+ ++ +Y D + SA +H +K+ V I K DNNC++ L L
Sbjct 1543 AIDIDWQAHYGFRDAAAF----SASSH-DAYKFEVVTHSNFIVHKQTDNNCWINAICLAL 1597
Query 1684 QQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDS 1743
Q+++ ++ P ++ + + F ++ GE GD E M + +
Sbjct 1598 QRLKPQWKFPGVRGLWNEFLERKTQGFVHMLYHISGVKKGEPGDA-ELMLHKLGDLMDND 1656
Query 1744 CKRVL--NVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQE 1801
C+ ++ C C + + + V A L+ G C G + Q +
Sbjct 1657 CEIIVTHTTACDKCAKVEKFVGPVVA----APLAIH----GTDETCVHGVSVNVKVTQIK 1708
Query 1802 SPFVMMS--APPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETL 1845
+ S P L+ + C Y+G+ + GHY + ++ L
Sbjct 1709 GTVAITSLIGPIIGEVLEATGYIC---YSGSNRNGHYTYYDNRNGL 1751
>sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=1a PE=3
SV=1
Length=3951
Score = 1113 bits (2878), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 781/2420 (32%), Positives = 1209/2420 (50%), Gaps = 232/2420 (10%)
Query 2080 ANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIA 2139
A N +K+ +++G + ++ + KPN L R+ + A G + V + I
Sbjct 1626 AENFVKMGDKIGGVTMGLWRAEH----LNKPN-LERIFNIAKKAIVGSSVVTTQCGKLIG 1680
Query 2140 NYAKPFLNKVVSTTTNIVTRCLNRVC--------TNYMPYFF-TLLLQLCTFTRSTNSRI 2190
A +KV +T + +C P F TL+ L F +++ +
Sbjct 1681 KAATFIADKVGGGVVRNITDSIKGLCGITRGHFERKMSPQFLKTLMFFLFYFLKASVKSV 1740
Query 2191 KASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAAL 2250
AS T + K + ++ +I+WF+ S ++++ +
Sbjct 1741 VASYKTVLCKVVLATL----------------------LIVWFVYTS---NPVMFTGIRV 1775
Query 2251 GVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQIT 2310
+ L S C Y++ +S +V YC C VCL DSL Y +++
Sbjct 1776 ---LDFLFEGSLCGPYKDYGKDSFDVL--RYCADDFICRVCLHDKDSLHLYKHAYSVEQV 1830
Query 2311 ISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAIMQLFFSYFAVHFISNSWLMWLI 2368
A G + W Y++F F V G I Y + + NS ++
Sbjct 1831 YKD-----AASGFIFNWNWLYLVFLILFVKPVAGFVII-----CYCVKYLVLNSTVLQTG 1880
Query 2369 INLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVVDGCNSSTCMMCYKRNRATRVEC 2423
+ + + + + F + +Y W Y VH + C TC +C + R+ R E
Sbjct 1881 VCFLDWF-VQTVFSHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEV 1939
Query 2424 TTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINP 2483
+ +V G ++ +VY N G FCK HNW C NCD + +TF+S EVA +LS + KR + P
Sbjct 1940 SVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKP 1999
Query 2484 TDQSSYIVDSVTVKNGSIHLYFDKAGQ-KTYERHSLSHFVNLDNLR-ANNTKGSLPINVI 2541
T + ++VD + + ++L + A K ++ F D L+ A K +L I
Sbjct 2000 TAYAYHVVDEACLVDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQI 2059
Query 2542 VFDGKSKCEESSA------KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYV 2595
DG C SA K+A++YY+Q +C+PIL+LDQAL ++ V+
Sbjct 2060 SNDGFIVCNTQSAHALEEAKNAAIYYAQYLCKPILILDQALYE------QLVVE------ 2107
Query 2596 NTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVECL 2655
P+ K +++ + L+ +S+D + + + + S + ++ V+
Sbjct 2108 ---------PVSK--SVIDKVCSILSSIISVDTAALNYKAGTLRDALLSITKDEEAVDMA 2156
Query 2656 KLSHQSDIEVTGDSCNNYMLTYN-KVENMTPRDLGACIDCSARHINAQVAKSHNIALIWN 2714
H D++ TGD N + +Y +TPRD G I+ A N +V + + +W
Sbjct 2157 IFCHNHDVDYTGDGFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAPPV--VWK 2214
Query 2715 VKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL--KGGKIVNN---W 2769
+ + LS+ K + SA K+ + F +T + +QV+ T K+ + K G IV+
Sbjct 2215 FSELIKLSDSCLKYLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKC 2274
Query 2770 LKQLIKVTLVF--LFVA---AIFYLITPVHVMSKHTDFSS--EIIGYKAIDGGVTRDIAS 2822
K K L+F LF A +Y+ + D +S + G+K ID GV R+I
Sbjct 2275 FKSYFKWLLIFYILFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVP 2334
Query 2823 TDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNG-DF 2881
DTCF+NK +FD ++ G Y N + CP++ AVI + G V G+PG + +G F
Sbjct 2335 EDTCFSNKFVNFDAFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMF 2390
Query 2882 LH---------FLPRVFS--AVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPV 2930
+H ++P F+ VG YT +I F TS + +A C ++ AS P
Sbjct 2391 IHMTQTERKPWYIPTWFNREIVG---YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQ 2446
Query 2931 PYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTC 2989
YC++ N G++ + S+ P Y +G + P L V DS YCR C
Sbjct 2447 LYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQILHTPYVVKFVSDS-YCRGSVC 2505
Query 2990 ERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVA 3049
E + G CVS + +WVL ND Y S PGVFCG L+ +M + + +I +
Sbjct 2506 EYTRPGYCVSLNPQWVLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLAT 2564
Query 3050 GGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIY 3109
++ +VV + ++F+ F Y+ V L+++++ +LC+ S L + V+Y
Sbjct 2565 MFLILVVVVLIFAMVIKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLY 2624
Query 3110 LYLTFYLTNDVSFLAHIQWMVMFTPLVPFWIT---IAYIICISTKHFYWFFSNYLKRRVV 3166
Y + + + + H + F +VP W+ + +II + T F W + R +
Sbjct 2625 CYASLVTSRNTVIIMHCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKL 2684
Query 3167 FNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTS 3225
++G F ++ AA TF++ ++KL +++ ++ YL+ Y + KY+SG
Sbjct 2685 YDGNEFVGNYDLAAKSTFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQD 2741
Query 3226 YREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTC 3285
Y +A LA AL+ + NSG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+
Sbjct 2742 YLQACRAWLAYALDQYRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSY 2801
Query 3286 GTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLIRKSNHNFLVQAGN-VQLRVIGH 3343
LNGLWL D +YCPRHV+ S D N D+L +NH F V + V L V+
Sbjct 2802 RGNNLNGLWLGDTIYCPRHVLGKFSGDQWN----DVLNLANNHEFEVTTQHGVTLNVVSR 2857
Query 3344 SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSF 3403
++ VL L+ AN +TPKYKF++ G +F++ Y G+ G+Y MR N TI+ SF
Sbjct 2858 RLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASF 2917
Query 3404 LNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTI 3463
L G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G FYG +VD + AQ D +
Sbjct 2918 LAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLV 2977
Query 3464 TVNVLAWLYAAVINGD-------RWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPL 3516
T N++AWLYAA+I+ +W L T +++D+N A + P + + L
Sbjct 2978 TNNIVAWLYAAIISVKESSFSLPKW-LESTTVSVDDYNKWAGDNGFTPFSTSTA--ITKL 3034
Query 3517 SAQTGIAVLDMCASLKELL--QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKR 3574
SA TG+ D+C L+ ++ + G ILG EDE TP V Q GV QS+ R
Sbjct 3035 SAITGV---DVCKLLRTIMVKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSFVR 3091
Query 3575 TIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKH 3631
+ W +L L L +V T L F++Y L A+ I+ + VKH
Sbjct 3092 KAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFT------VKH 3144
Query 3632 KHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRIMTWLDMV--DTSL-------- 3674
A++ FLLP+L TV A +Y + + V+ + W D V DT +
Sbjct 3145 VMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPLV 3204
Query 3675 --SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAI 3731
+ FK ++ C M + LL+L + ++T N LT + GN
Sbjct 3205 LYTAFKCVQGCYMNSFNTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN------ 3251
Query 3732 SMWALII-----SVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFL 3786
W L +V +N S +F+ + +M + YC ++ L +M V C +
Sbjct 3252 --WELFFELVHTTVLANVSSNSLIGLFVFKCAKWM-LYYCNATYLNNYVLMAVM-VNC-I 3306
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G
Sbjct 3307 GWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQG 3366
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG + +ATVQ+K+SDVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E
Sbjct 3367 IGGDRVLPIATVQAKLSDVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGE 3426
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
+ ++ +L L + +D+++ C+++L LQ++ EFS +PSYA + A+ YE+
Sbjct 3427 CMDNLLGMLITLFCIDSTIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEK 3486
Query 3967 AVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKR 4022
+ + G ++ L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+R
Sbjct 3487 VLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRR 3546
Query 4023 AKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKN 4082
AK+ S++ +LF+ML+K+D++ LN + + A G VPL +P+ + KL +VIPD T+
Sbjct 3547 AKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVK 3606
Query 4083 TCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-----NSPNLAWPLIVTALRANSA- 4136
+G TY++ +W I V+DAD + + + N+AWPL V R
Sbjct 3607 CVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNK 3666
Query 4137 --VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
V LQNNEL P ++ +C AG Q C+ ++ YY G V A+ S +LK A
Sbjct 3667 VDVVLQNNELMPHGVKTKACVAGVDQAHCSVESK-CYYTNISGNSVVAAITSSNPNLKVA 3725
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
F G IY +L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+
Sbjct 3726 SFLNEAGN-QIYVDLDPPCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQS 3784
Query 4255 -GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
G+ TE +LS C+FAVD A Y Y+A+G QP+ NCVKML H G+G AIT P
Sbjct 3785 KGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPS 3844
Query 4314 ANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
DQ+S+GGAS CLYCR HI HP N G C KG +VQIPTT DPVGF L+N V
Sbjct 3845 PTPDQDSYGGASVCLYCRAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKV 3903
Query 4370 CTVCGMWKGYGCSCDQLREP 4389
CTVC W GYGC CD LR+P
Sbjct 3904 CTVCQCWIGYGCQCDSLRQP 3923
Score = 68.2 bits (165), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 57/243 (23%), Positives = 107/243 (44%), Gaps = 15/243 (6%)
Query 1570 VFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRV 1629
++ T D + + V+ + GQ FG Y V + + + YV D ++
Sbjct 1180 IYLTEDGVKYRSIVLKPGDSLGQ-FGQVYAKNKIV--FTADDVEDKEILYVPTTDKSI-- 1234
Query 1630 EAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELK 1689
EYY ++ Y+ L +KW + ++W D NC++++A++ LQ +++
Sbjct 1235 --LEYYGLDAQKYV-IYLQTL--AQKWNVQYRDNFLILEWRDGNCWISSAIVLLQAAKIR 1289
Query 1690 FNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLN 1749
F L +A+ + G+ +F A A C VG+ D ++ L +H + D L
Sbjct 1290 FK-GFLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFSDANWLLANLAEHFDADYTNAFLK 1348
Query 1750 --VVCKTCGQQQTTLKGVEA-VMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVM 1806
V C CG + L+G+EA + + + FK TCG T +++ P+++
Sbjct 1349 KRVSC-NCGIKSYELRGLEACIQPVRATNLLHFKTQYSNCPTCGANNTDEVIEASLPYLL 1407
Query 1807 MSA 1809
+ A
Sbjct 1408 LFA 1410
Score = 54.3 bits (129), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 53/192 (28%), Positives = 87/192 (45%), Gaps = 20/192 (10%)
Query 985 QQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV---QTIEVNSFSGYLKLTDNVYIK 1041
++ V Q+DG++ Q + I V+PQ E + T E F Y ++ +
Sbjct 971 EEVVSQKDGAQIKQ----EPIQVVKPQREKKAKKFKVKPATCEKPKFLEYKTCVGDLTVV 1026
Query 1042 NADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGG 1101
A ++E K+ +VNAAN ++ HG GVA A+ +DY+ +GP +
Sbjct 1027 IAKALDEFKEF---CIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ--- 1080
Query 1102 SCVLSGHNLAKHCL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGADP 1158
V C+ +VVGP + L +AY+N V+ + P+LS GIFG D
Sbjct 1081 RLVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGVD- 1139
Query 1159 IHSLRVCVDTVR 1170
++ +D +R
Sbjct 1140 ---FKMSIDAMR 1148
>sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=1a PE=1 SV=1
Length=3951
Score = 1113 bits (2878), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 781/2420 (32%), Positives = 1209/2420 (50%), Gaps = 232/2420 (10%)
Query 2080 ANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIA 2139
A N +K+ +++G + ++ + KPN L R+ + A G + V + I
Sbjct 1626 AENFVKMGDKIGGVTMGLWRAEH----LNKPN-LERIFNIAKKAIVGSSVVTTQCGKLIG 1680
Query 2140 NYAKPFLNKVVSTTTNIVTRCLNRVC--------TNYMPYFF-TLLLQLCTFTRSTNSRI 2190
A +KV +T + +C P F TL+ L F +++ +
Sbjct 1681 KAATFIADKVGGGVVRNITDSIKGLCGITRGHFERKMSPQFLKTLMFFLFYFLKASVKSV 1740
Query 2191 KASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAAL 2250
AS T + K + ++ +I+WF+ S ++++ +
Sbjct 1741 VASYKTVLCKVVLATL----------------------LIVWFVYTS---NPVMFTGIRV 1775
Query 2251 GVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQIT 2310
+ L S C Y++ +S +V YC C VCL DSL Y +++
Sbjct 1776 ---LDFLFEGSLCGPYKDYGKDSFDVL--RYCADDFICRVCLHDKDSLHLYKHAYSVEQV 1830
Query 2311 ISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAIMQLFFSYFAVHFISNSWLMWLI 2368
A G + W Y++F F V G I Y + + NS ++
Sbjct 1831 YKD-----AASGFIFNWNWLYLVFLILFVKPVAGFVII-----CYCVKYLVLNSTVLQTG 1880
Query 2369 INLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVVDGCNSSTCMMCYKRNRATRVEC 2423
+ + + + + F + +Y W Y VH + C TC +C + R+ R E
Sbjct 1881 VCFLDWF-VQTVFSHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEV 1939
Query 2424 TTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINP 2483
+ +V G ++ +VY N G FCK HNW C NCD + +TF+S EVA +LS + KR + P
Sbjct 1940 SVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKP 1999
Query 2484 TDQSSYIVDSVTVKNGSIHLYFDKAGQ-KTYERHSLSHFVNLDNLR-ANNTKGSLPINVI 2541
T + ++VD + + ++L + A K ++ F D L+ A K +L I
Sbjct 2000 TAYAYHVVDEACLVDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQI 2059
Query 2542 VFDGKSKCEESSA------KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYV 2595
DG C SA K+A++YY+Q +C+PIL+LDQAL ++ V+
Sbjct 2060 SNDGFIVCNTQSAHALEEAKNAAIYYAQYLCKPILILDQALYE------QLVVE------ 2107
Query 2596 NTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVECL 2655
P+ K +++ + L+ +S+D + + + + S + ++ V+
Sbjct 2108 ---------PVSK--SVIDKVCSILSSIISVDTAALNYKAGTLRDALLSITKDEEAVDMA 2156
Query 2656 KLSHQSDIEVTGDSCNNYMLTYN-KVENMTPRDLGACIDCSARHINAQVAKSHNIALIWN 2714
H D++ TGD N + +Y +TPRD G I+ A N +V + + +W
Sbjct 2157 IFCHNHDVDYTGDGFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAPPV--VWK 2214
Query 2715 VKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL--KGGKIVNN---W 2769
+ + LS+ K + SA K+ + F +T + +QV+ T K+ + K G IV+
Sbjct 2215 FSELIKLSDSCLKYLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKC 2274
Query 2770 LKQLIKVTLVF--LFVA---AIFYLITPVHVMSKHTDFSS--EIIGYKAIDGGVTRDIAS 2822
K K L+F LF A +Y+ + D +S + G+K ID GV R+I
Sbjct 2275 FKSYFKWLLIFYILFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVP 2334
Query 2823 TDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNG-DF 2881
DTCF+NK +FD ++ G Y N + CP++ AVI + G V G+PG + +G F
Sbjct 2335 EDTCFSNKFVNFDAFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMF 2390
Query 2882 LH---------FLPRVFS--AVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPV 2930
+H ++P F+ VG YT +I F TS + +A C ++ AS P
Sbjct 2391 IHMTQTERKPWYIPTWFNREIVG---YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQ 2446
Query 2931 PYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTC 2989
YC++ N G++ + S+ P Y +G + P L V DS YCR C
Sbjct 2447 LYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQILHTPYVVKFVSDS-YCRGSVC 2505
Query 2990 ERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVA 3049
E + G CVS + +WVL ND Y S PGVFCG L+ +M + + +I +
Sbjct 2506 EYTRPGYCVSLNPQWVLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLAT 2564
Query 3050 GGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIY 3109
++ +VV + ++F+ F Y+ V L+++++ +LC+ S L + V+Y
Sbjct 2565 MFLILVVVVLIFAMVIKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLY 2624
Query 3110 LYLTFYLTNDVSFLAHIQWMVMFTPLVPFWIT---IAYIICISTKHFYWFFSNYLKRRVV 3166
Y + + + + H + F +VP W+ + +II + T F W + R +
Sbjct 2625 CYASLVTSRNTVIIMHCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKL 2684
Query 3167 FNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTS 3225
++G F ++ AA TF++ ++KL +++ ++ YL+ Y + KY+SG
Sbjct 2685 YDGNEFVGNYDLAAKSTFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQD 2741
Query 3226 YREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTC 3285
Y +A LA AL+ + NSG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+
Sbjct 2742 YLQACRAWLAYALDQYRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSY 2801
Query 3286 GTTTLNGLWLDDVVYCPRHVICT-SEDMLNPNYEDLLIRKSNHNFLVQAGN-VQLRVIGH 3343
LNGLWL D +YCPRHV+ S D N D+L +NH F V + V L V+
Sbjct 2802 RGNNLNGLWLGDTIYCPRHVLGKFSGDQWN----DVLNLANNHEFEVTTQHGVTLNVVSR 2857
Query 3344 SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSF 3403
++ VL L+ AN +TPKYKF++ G +F++ Y G+ G+Y MR N TI+ SF
Sbjct 2858 RLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASF 2917
Query 3404 LNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTI 3463
L G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G FYG +VD + AQ D +
Sbjct 2918 LAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLV 2977
Query 3464 TVNVLAWLYAAVINGD-------RWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPL 3516
T N++AWLYAA+I+ +W L T +++D+N A + P + + L
Sbjct 2978 TNNIVAWLYAAIISVKESSFSLPKW-LESTTVSVDDYNKWAGDNGFTPFSTSTA--ITKL 3034
Query 3517 SAQTGIAVLDMCASLKELL--QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKR 3574
SA TG+ D+C L+ ++ + G ILG EDE TP V Q GV QS+ R
Sbjct 3035 SAITGV---DVCKLLRTIMVKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSFVR 3091
Query 3575 TIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKH 3631
+ W +L L L +V T L F++Y L A+ I+ + VKH
Sbjct 3092 KAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFT------VKH 3144
Query 3632 KHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRIMTWLDMV--DTSL-------- 3674
A++ FLLP+L TV A +Y + + V+ + W D V DT +
Sbjct 3145 VMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPLV 3204
Query 3675 --SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAI 3731
+ FK ++ C M + LL+L + ++T N LT + GN
Sbjct 3205 LYTAFKCVQGCYMNSFNTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN------ 3251
Query 3732 SMWALII-----SVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFL 3786
W L +V +N S +F+ + +M + YC ++ L +M V C +
Sbjct 3252 --WELFFELVHTTVLANVSSNSLIGLFVFKCAKWM-LYYCNATYLNNYVLMAVM-VNC-I 3306
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G
Sbjct 3307 GWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQG 3366
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG + +ATVQ+K+SDVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E
Sbjct 3367 IGGDRVLPIATVQAKLSDVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGE 3426
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
+ ++ +L L + +D+++ C+++L LQ++ EFS +PSYA + A+ YE+
Sbjct 3427 CMDNLLGMLITLFCIDSTIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEK 3486
Query 3967 AVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKR 4022
+ + G ++ L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+R
Sbjct 3487 VLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRR 3546
Query 4023 AKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKN 4082
AK+ S++ +LF+ML+K+D++ LN + + A G VPL +P+ + KL +VIPD T+
Sbjct 3547 AKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVK 3606
Query 4083 TCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-----NSPNLAWPLIVTALRANSA- 4136
+G TY++ +W I V+DAD + + + N+AWPL V R
Sbjct 3607 CVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNK 3666
Query 4137 --VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
V LQNNEL P ++ +C AG Q C+ ++ YY G V A+ S +LK A
Sbjct 3667 VDVVLQNNELMPHGVKTKACVAGVDQAHCSVESK-CYYTNISGNSVVAAITSSNPNLKVA 3725
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
F G IY +L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+
Sbjct 3726 SFLNEAGN-QIYVDLDPPCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQS 3784
Query 4255 -GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
G+ TE +LS C+FAVD A Y Y+A+G QP+ NCVKML H G+G AIT P
Sbjct 3785 KGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPS 3844
Query 4314 ANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
DQ+S+GGAS CLYCR HI HP N G C KG +VQIPTT DPVGF L+N V
Sbjct 3845 PTPDQDSYGGASVCLYCRAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKV 3903
Query 4370 CTVCGMWKGYGCSCDQLREP 4389
CTVC W GYGC CD LR+P
Sbjct 3904 CTVCQCWIGYGCQCDSLRQP 3923
Score = 68.2 bits (165), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 57/243 (23%), Positives = 107/243 (44%), Gaps = 15/243 (6%)
Query 1570 VFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRV 1629
++ T D + + V+ + GQ FG Y V + + + YV D ++
Sbjct 1180 IYLTEDGVKYRSIVLKPGDSLGQ-FGQVYAKNKIV--FTADDVEDKEILYVPTTDKSI-- 1234
Query 1630 EAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELK 1689
EYY ++ Y+ L +KW + ++W D NC++++A++ LQ +++
Sbjct 1235 --LEYYGLDAQKYV-IYLQTL--AQKWNVQYRDNFLILEWRDGNCWISSAIVLLQAAKIR 1289
Query 1690 FNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLN 1749
F L +A+ + G+ +F A A C VG+ D ++ L +H + D L
Sbjct 1290 FK-GFLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFSDANWLLANLAEHFDADYTNAFLK 1348
Query 1750 --VVCKTCGQQQTTLKGVEA-VMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVM 1806
V C CG + L+G+EA + + + FK TCG T +++ P+++
Sbjct 1349 KRVSC-NCGIKSYELRGLEACIQPVRATNLLHFKTQYSNCPTCGANNTDEVIEASLPYLL 1407
Query 1807 MSA 1809
+ A
Sbjct 1408 LFA 1410
Score = 54.3 bits (129), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 53/192 (28%), Positives = 87/192 (45%), Gaps = 20/192 (10%)
Query 985 QQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV---QTIEVNSFSGYLKLTDNVYIK 1041
++ V Q+DG++ Q + I V+PQ E + T E F Y ++ +
Sbjct 971 EEVVSQKDGAQIKQ----EPIQVVKPQREKKAKKFKVKPATCEKPKFLEYKTCVGDLTVV 1026
Query 1042 NADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGG 1101
A ++E K+ +VNAAN ++ HG GVA A+ +DY+ +GP +
Sbjct 1027 IAKALDEFKEF---CIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ--- 1080
Query 1102 SCVLSGHNLAKHCL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGADP 1158
V C+ +VVGP + L +AY+N V+ + P+LS GIFG D
Sbjct 1081 RLVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGVD- 1139
Query 1159 IHSLRVCVDTVR 1170
++ +D +R
Sbjct 1140 ---FKMSIDAMR 1148
>sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=1a PE=1 SV=1
Length=3953
Score = 1108 bits (2866), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 752/2260 (33%), Positives = 1146/2260 (51%), Gaps = 192/2260 (8%)
Query 2229 IIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPC 2288
+I+WF+ S ++++ + + L S C Y + +S +V YC G C
Sbjct 1759 LIVWFIYTS---NPVVFTGIRV---LDFLFEGSLCGPYNDYGKDSFDVL--RYCAGDFTC 1810
Query 2289 SVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAI 2346
VCL DSL Y +++ A G+ W Y++F F V G I
Sbjct 1811 RVCLHDRDSLHLYKHAYSVEQIYKD-----AASGINFNWNWLYLVFLILFVKPVAGFVII 1865
Query 2347 MQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVV 2401
Y + + +S ++ + + + + + F + +Y W Y VH +
Sbjct 1866 -----CYCVKYLVLSSTVLQTGVGFLDWF-VKTVFTHFNFMGAGFYFWLFYKIYVQVHHI 1919
Query 2402 DGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAG 2461
C TC +C + R+ R E + +V G ++ +VY N G FCK HNW C NCD +
Sbjct 1920 LYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQ 1979
Query 2462 STFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKA-GQKTYERHSLSH 2520
+TF+S EVA +LS + KR + PT + ++V V + ++L + A K ++
Sbjct 1980 NTFMSPEVAGELSEKLKRHVKPTAYAYHVVYEACVVDDFVNLKYKAAIPGKDNASSAVKC 2039
Query 2521 FVNLDNLR-ANNTKGSLPINVIVFDGKSKCEESSA------KSASVYYSQLMCQPILLLD 2573
F D L+ A K +L I DG C SA K+A+VYY+Q +C+PIL+LD
Sbjct 2040 FSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSAHALEEAKNAAVYYAQYLCKPILILD 2099
Query 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
QAL + P+ K +++ + L+ +S+D +
Sbjct 2100 QAL---------------------YEQLIVEPVSK--SVIDKVCSILSNIISVDTAALNY 2136
Query 2634 ISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYN-KVENMTPRDLGACI 2692
+ + + S + ++ V+ H ++E TGD N + +Y + +TPRD G I
Sbjct 2137 KAGTLRDALLSITKDEEAVDMAIFCHNHEVEYTGDGFTNVIPSYGMDTDKLTPRDRGFLI 2196
Query 2693 DCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVN 2752
+ A N +V + + +W D + LS+ K + SA K+ F +T + +QV++
Sbjct 2197 NADASIANLRVKNAPPV--VWKFSDLIKLSDSCLKYLISATVKSGGRFFITKSGAKQVIS 2254
Query 2753 VVTTKIAL--KGGKIVNN---WLKQLIKVTLVF--LFVA---AIFYLITPVHVMSKHTDF 2802
T K+ + K G ++NN W K VF LF A +Y+ + D
Sbjct 2255 CHTQKLLVEKKAGGVINNTFKWFMSCFKWLFVFYILFTACCLGYYYMEMNKSFVHPMYDV 2314
Query 2803 SS--EIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITR 2860
+S + G+K ID GV R+I S D CF+NK +FD ++ G SY N+K CP++ VI
Sbjct 2315 NSTLHVEGFKVIDKGVIREIVSEDNCFSNKFVNFDAFW---GKSYENNKNCPIVTVVIDG 2371
Query 2861 EVGFVVPGLPGTILRTTNG-DFLH---------FLPRVFS--AVGNICYTPSKLIEYTDF 2908
+ G V G+PG + +G F+H ++P F+ VG YT +I F
Sbjct 2372 D-GTVAVGVPGFVSWVMDGVMFVHMTQTDRRPWYIPTWFNREIVG---YTQDSIITEGSF 2427
Query 2909 ATSACVLAAECTIFKDASGKPVPYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNT 2967
TS + +A C ++ AS P YC++ N G++ + S+ P Y +G + P
Sbjct 2428 YTSIALFSARC-LYLTASNTPQLYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQ 2486
Query 2968 YLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLL 3027
L V DS YCR CE ++ G CVS +WVL ND Y S PGVFCG L+
Sbjct 2487 ILHTPYIVKFVSDS-YCRGSVCEYTKPGYCVSLDSQWVLFNDEYISKPGVFCGSTVRELM 2545
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
NM + + +I + ++ +V+ + ++F+ F Y+ +V L++++
Sbjct 2546 FNMVSTFFTGVNP-NIYIQLATMFLILVVIVLIFAMVIKFQGVFKAYATIVFTIMLVWVI 2604
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWIT---IAY 3144
+ VLC+ S L + V+Y Y + + + + + H + F +VP W+ + +
Sbjct 2605 NAFVLCVHSYNSVLAVILLVLYCYASMVTSRNTAIIMHCWLVFTFGLIVPTWLACCYLGF 2664
Query 3145 IICISTKHFYWFFSNYLKRRVVFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQ 3203
I+ + T +W + R +++G F ++ AA TF++ ++KL +++ +
Sbjct 2665 ILYMYTPLVFWCYGTTKNTRKLYDGNEFVGNYDLAAKSTFVIRGTEFVKLTNEIG---DK 2721
Query 3204 YNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQ 3263
+ YL+ Y + KY+SG Y +A LA AL+ + NSG +V+Y PP+ SI + LQ
Sbjct 2722 FEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYALDQYRNSGVEVVYTPPRYSIGVSRLQ 2781
Query 3264 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIR 3323
+GF+K+ PS VE C+V V+ LNGLWL D +YCPRHV+ + D+L
Sbjct 2782 AGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVL---GKFSGDQWGDVLNL 2838
Query 3324 KSNHNFLVQAGN-VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYN 3382
+NH F V N V L V+ ++ VL L+ AN +TPKYKFV+ G +F++ Y
Sbjct 2839 ANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYG 2898
Query 3383 GSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3442
G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G
Sbjct 2899 GTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMG 2958
Query 3443 NFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVIN-------GDRWFLNRFTTTLNDFNL 3495
FYG +VD + AQ D +T N++AWLYAA+I+ +W L T ++ D+N
Sbjct 2959 EFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKW-LESTTVSIEDYNR 3017
Query 3496 VAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRT--ILGSALLEDE 3553
A + P + + LSA TG+ D+C L+ ++ + ILG EDE
Sbjct 3018 WASDNGFTPFSTSTA--ITKLSAITGV---DVCKLLRTIMVKSAQWGSDPILGQYNFEDE 3072
Query 3554 FTPFDVVRQCSGVTFQSAVKRTIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENA 3610
TP V Q GV QS+ R + W +L L L +V T L F+++
Sbjct 3073 LTPESVFNQVGGVRLQSSFVRKAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVHAAV 3131
Query 3611 FLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRI 3663
L A+ I+ + VKH A++ FLLP+L TV A +Y + + V+ +
Sbjct 3132 ILLMAVLFISFT------VKHVMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFL 3185
Query 3664 MTWLDMV--DTSL----------SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWT 3710
W D V DT + + FK ++ C M + LL+L + ++T
Sbjct 3186 SQWYDPVVFDTMVPWMLLPLVLYTAFKCVQGCYMNSFNTSLLMLYQFMKL----GFVIYT 3241
Query 3711 LMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVE----YC 3766
N LT + GN W L + + L IVF C + YC
Sbjct 3242 SSNTLTAYTE---GN--------WELFFELVHTIVLANVSSNSLIGLIVFKCAKWMLYYC 3290
Query 3767 PIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQ 3826
+ L +M+ +G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM
Sbjct 3291 NATYFNNYVLMAVMV--NGIGWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLH 3348
Query 3827 GLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSK 3886
+ PPK + F NI + G+GG + +ATVQSK+SDVKCT+VVL+ +L +L VE++SK
Sbjct 3349 KVNPPKTVWEVFTTNILIQGIGGDRVLPIATVQSKLSDVKCTTVVLMQLLTKLNVEANSK 3408
Query 3887 LWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIAS 3946
+ A V+LHN IL + D E + ++ +L L + +D+ + C+++L LQ++
Sbjct 3409 MHAYLVELHNKILASDDVGECMDNLLGMLITLFCIDSTIDLGEYCDDILKRSTVLQSVTQ 3468
Query 3947 EFSSLPSYAAFATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLE 4002
EFS +PSYA + A+ YE+ +A+ G ++ L +K+ N+AKS FDRD A+Q+KL+
Sbjct 3469 EFSHIPSYAEYERAKSIYEKVLADSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLD 3528
Query 4003 KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII 4062
MA++AMT MYK+AR D+RAK+ S++ +LF+ML+K+D++ LN + + A G VPL +
Sbjct 3529 SMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLFDQANSGVVPLATV 3588
Query 4063 PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD----- 4117
P+ + KL +VIPD T+ +G TY++ +W I V DAD + +
Sbjct 3589 PIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDCVTDADGTELHPTSTGSGLTYCI 3648
Query 4118 NSPNLAWPLIVTALRANSA---VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNT 4174
+ N+AWPL V R V LQNNEL P ++ +C AG Q C+ ++ YY +
Sbjct 3649 SGDNIAWPLKVNLTRNGHNKVDVALQNNELMPHGVKTKACVAGVDQAHCSVESK-CYYTS 3707
Query 4175 TKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGL 4234
G V A+ S +LK A F G IY +L+PPC+F +V YLYFIK
Sbjct 3708 ISGSSVVAAITSSNPNLKVASFLNEAGN-QIYVDLDPPCKFGMKVGDKVEVVYLYFIKNT 3766
Query 4235 NNLNRGMVLGSLAATVRLQA-GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITN 4293
++ RGMVLG+++ V LQ+ G+ TE +LS C+FAVD A Y Y+A+G QP+ N
Sbjct 3767 RSIVRGMVLGAISNVVVLQSKGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGN 3826
Query 4294 CVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKY 4349
CVKML H G+G AIT P DQ+S+GGAS CLYCR HI HP N G C KG +
Sbjct 3827 CVKMLTVHNGSGFAITSKPSPTPDQDSYGGASVCLYCRAHIAHPGGAGNLDGRCQFKGSF 3886
Query 4350 VQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREP 4389
VQIPTT DPVGF L+N VCTVC W GYGC CD LR+P
Sbjct 3887 VQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGCQCDSLRQP 3925
Score = 72.4 bits (176), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 57/242 (24%), Positives = 108/242 (45%), Gaps = 13/242 (5%)
Query 1570 VFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRV 1629
++ T D + + V+ + GQ FG + A + + E K +P D +
Sbjct 1182 IYLTEDGVKYRSVVLKPGDSLGQ-FGQVF---ARNKVVFSADDVEDKEILFIPTTDKTIL 1237
Query 1630 EAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELK 1689
E Y+ D Y+ L +KW + ++W D NC++++A++ LQ +++
Sbjct 1238 E----YYGLDAQKYVTYLQTL--AQKWDVQYRDNFVILEWRDGNCWISSAIVLLQAAKIR 1291
Query 1690 FNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVL- 1748
F L +A+ + G+ +F A A CN VG+ D ++ L +H + D +L
Sbjct 1292 FK-GFLAEAWAKLLGGDPTDFVAWCYASCNAKVGDFSDANWLLANLAEHFDADYTNALLK 1350
Query 1749 NVVCKTCGQQQTTLKGVEA-VMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM 1807
V CG + L+G+EA + + + FK TCG +T +++ P++++
Sbjct 1351 KCVSCNCGVKSYELRGLEACIQPVRAPNLLHFKTQYSNCPTCGASSTDEVIEASLPYLLL 1410
Query 1808 SA 1809
A
Sbjct 1411 FA 1412
Score = 51.6 bits (122), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 50/180 (28%), Positives = 80/180 (44%), Gaps = 28/180 (16%)
Query 1009 QPQLEMELTPVVQ---------------TIEVNSFSGYLKLTDNVYIKNADIVEEAKKVK 1053
+PQ+E E T VV+ T E F Y ++ + A ++E K+
Sbjct 981 EPQVEQEPTLVVKAQREKKAKKFKVKPATCEKPKFLEYKTCVGDLAVVIAKALDEFKEF- 1039
Query 1054 PTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKH 1113
+VNAAN ++ HGGGVA A+ DY+ +GP + V
Sbjct 1040 --CIVNAANEHMSHGGGVAKAIADFCGPDFVEYCADYVKKHGPQQ---KLVTPSFVKGIQ 1094
Query 1114 CL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGADPIHSLRVCVDTVR 1170
C+ +VVGP + L +AY++ V+ + P+LS+GIFG D ++ +D +R
Sbjct 1095 CVNNVVGPRHGDSNLREKLVAAYKSVLVGGVVNYVVPVLSSGIFGVD----FKISIDAMR 1150
>sp|P18457|R1AB_CVPFS Replicase polyprotein 1ab (Fragment) OS=Porcine
transmissible gastroenteritis coronavirus (strain FS772/70)
OX=11150 GN=rep PE=3 SV=1
Length=533
Score = 518 bits (1334), Expect = 2e-162, Method: Compositional matrix adjust.
Identities = 266/526 (51%), Positives = 364/526 (69%), Gaps = 8/526 (2%)
Query 6575 FDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNG--VTLIGEAVKTQFNYYK 6632
FD + G + F R+ VLI+ +VKGL ++ + LN V+ +G T + Y +
Sbjct 9 FDNSIAGSFERFTTTRDAVLISNNAVKGLS-AIKLQYGLLNDLPVSTVGNKPVTWYIYVR 67
Query 6633 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 6692
K V+Q+ ++Y+TQ R + FKPRS ME DFL + FI++Y LE Y FEH+V+GD
Sbjct 68 KNGEYVEQI-DSYYTQGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEHVVFGDV 126
Query 6693 SHSQLGGLHLLIGLAKRFKESPFELEDFIP-MDSTVKNYFITDAQTGSSKCVCSVIDLLL 6751
S + +GG+HLLI + K F +++F+ DST+K+ IT A SSK VC+ +D+LL
Sbjct 127 SKTTIGGMHLLISQVRLAKMGLFSVQEFMNNSDSTLKSCCITYADDPSSKNVCTYMDILL 186
Query 6752 DDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPN 6811
DDFV IIKS DL+VVSKVV V +D +MLWC++ H++TFYP+LQS++ W PG +MP
Sbjct 187 DDFVTIIKSLDLNVVSKVVDVIVDCKAWKWMLWCENSHIKTFYPQLQSAE-WNPGYSMPT 245
Query 6812 LYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAG 6871
LYK+QRM LE+C+L NYG LP GI NV KYTQLCQYLNT TL VP+ MRV+H GA
Sbjct 246 LYKIQRMCLERCNLYNYGAQVKLPDGITTNVVKYTQLCQYLNTTTLCVPHKMRVLHLGAA 305
Query 6872 SDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYD 6931
GVAPG+ VLR+WLP +LVD+DL D+VSDAD ++ GDC +++ +K+DL++SD+YD
Sbjct 306 GASGVAPGSTVLRRWLPDDAILVDNDLRDYVSDADFSVTGDCTSLYIEDKFDLLVSDLYD 365
Query 6932 PKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAF 6991
TK++ EN SK+GFFTYI GFI++KL+LGGSVAIKITE SWN DLY+L+ F +WT F
Sbjct 366 GSTKSIDGENTSKDGFFTYINGFIKEKLSLGGSVAIKITEFSWNKDLYELIQRFEYWTVF 425
Query 6992 VTNVNASSSEAFLIGCNYLGK--PREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFP 7049
T+VN SSSE FLIG NYLG + +DG +MHANYIFWRN+ + LS S+ D KF
Sbjct 426 CTSVNTSSSEGFLIGINYLGPYCDKAIVDGNIMHANYIFWRNSTIMALSHNSVLDTPKFK 485
Query 7050 LKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
+ +++LKE ++N+M++ LL KG+L+IR N +++ + VN
Sbjct 486 CRCNNALIVNLKEKELNEMVIGLLRKGKLLIRNNGKLLNFGNHFVN 531
>sp|Q9WQ77|R1AB_CVRSD Replicase polyprotein 1ab (Fragment) OS=Rat
coronavirus (strain 681) OX=33740 GN=rep PE=3 SV=1
Length=307
Score = 484 bits (1246), Expect = 4e-154, Method: Compositional matrix adjust.
Identities = 225/307 (73%), Positives = 266/307 (87%), Gaps = 0/307 (0%)
Query 4898 FNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICST 4957
FNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI ST
Sbjct 1 FNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILST 60
Query 4958 MTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRA 5017
MT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPKCDRA
Sbjct 61 MTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPKCDRA 120
Query 5018 MPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDA 5077
MPN+LRI++SLVLARKH +CCS + RFYRLANECAQVLSE+VMCGG YVKPGGTSSGDA
Sbjct 121 MPNILRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLSEIVMCGGCYYVKPGGTSSGDA 180
Query 5078 TTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEF 5137
TTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD FV+E+
Sbjct 181 TTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVSEY 240
Query 5138 YAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDL 5197
Y +L KHFSMMILSDD VVC+NS +AS+G +A+I F+ VLYYQNNVFMSEAKCW ETD+
Sbjct 241 YEFLNKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQVLYYQNNVFMSEAKCWVETDI 300
Query 5198 TKGPHEF 5204
KGPHEF
Sbjct 301 EKGPHEF 307
>sp|Q9WQ76|R1AB_CVTMI Replicase polyprotein 1ab (Fragment) OS=Turkey
coronavirus (strain Minnesota) OX=231430 GN=rep PE=3
SV=1
Length=306
Score = 445 bits (1145), Expect = 2e-140, Method: Compositional matrix adjust.
Identities = 213/307 (69%), Positives = 248/307 (81%), Gaps = 1/307 (0%)
Query 4898 FNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICST 4957
FNK+GKARLYY+ MS E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI ST
Sbjct 1 FNKFGKARLYYE-MSLEEQDQLFESTKKNVLPTITQMNLKYAISAKNRARTVAGVSILST 59
Query 4958 MTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRA 5017
MTNRQFHQK+LKSI TR A VVIGT+KFYGGW NML+ + VE+P LMGWDYPKCDRA
Sbjct 60 MTNRQFHQKILKSIVNTRNAPVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKCDRA 119
Query 5018 MPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDA 5077
MPN+LRI ASLVLARKHT CC+ S R YRL NECAQVLSE V+ G +YVKPGGTSSGDA
Sbjct 120 MPNLLRITASLVLARKHTNCCTWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSSGDA 179
Query 5078 TTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEF 5137
TTAYANSVFNI QA +ANV LLS I +++LQ+ LY+ +YR + D FV +F
Sbjct 180 TTAYANSVFNIIQATSANVARLLSVITRDIVYDDIKSLQYELYQQVYRRVNFDPAFVEKF 239
Query 5138 YAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDL 5197
Y+YL K+FS+MI +DD VVC+N+T A QGLVA I F+ +LYYQNNV+M+++KCW E DL
Sbjct 240 YSYLCKNFSLMIFADDGVVCYNNTLAKQGLVADISGFREILYYQNNVYMADSKCWVEPDL 299
Query 5198 TKGPHEF 5204
KGPHEF
Sbjct 300 EKGPHEF 306
>sp|P12723|R1AB_IBVK Replicase polyprotein 1ab (Fragment) OS=Avian
infectious bronchitis virus (strain KB8523) OX=11126 GN=rep
PE=3 SV=1
Length=521
Score = 439 bits (1129), Expect = 4e-135, Method: Compositional matrix adjust.
Identities = 234/473 (49%), Positives = 324/473 (68%), Gaps = 13/473 (3%)
Query 6631 YKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYG 6690
YK+V+G LP T TQ R+ + F+PRS +E DFL+++ ++F+E+Y + +HI+YG
Sbjct 50 YKRVNGAFVTLPNTLNTQGRSYETFEPRSDVERDFLDMSEEDFVEKYG-KDLGLQHILYG 108
Query 6691 DFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTV-KNYFITDAQTGSSKCVCSVIDL 6749
+ QLGGLH +IG+ + + + + DS V +NYF+ A GS K VC+V+DL
Sbjct 109 EVDKPQLGGLHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVL-ADNGSYKQVCTVVDL 167
Query 6750 LLDDFVEI---IKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPG 6806
LLDDF+E+ I ++ + SKVV V+IDY I+FM W +DG ++T YP+LQS AW G
Sbjct 168 LLDDFLELLRNILNEYGTNKSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQS--AWTCG 225
Query 6807 VAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVI 6866
MP LYK+Q ++E C++ NYG TLP GIMMNVAKYTQLCQYL+ T+ VP+NMRV+
Sbjct 226 YNMPELYKVQNCVMEPCNIPNYGVGITLPSGIMMNVAKYTQLCQYLSKTTVCVPHNMRVM 285
Query 6867 HFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLII 6926
HFGAGSDKGVAPG+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC T +K+DL+I
Sbjct 286 HFGAGSDKGVAPGSTVLKQWLPEGTLLVDTDIVDYVSDAHVSVLSDCNKYKTEHKFDLVI 345
Query 6927 SDMY---DPKTKN-VTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLM 6982
SDMY D K K+ N+ + F Y+ F++ LALGGS A+K+TE SW+ LY +
Sbjct 346 SDMYTDNDSKRKHGGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKLTETSWHESLYDIA 405
Query 6983 GHFAWWTAFVTNVNASSSEAFLIGCNYLGKP-REQIDGYVMHANYIFWRNTNPIQLSSYS 7041
AWWT F T VNASSSEAFLIG NYLG + ++ G +HANYIFWRN N +Q S+YS
Sbjct 406 QDCAWWTMFCTAVNASSSEAFLIGVNYLGASVKVKVSGKTLHANYIFWRNCNYLQTSAYS 465
Query 7042 LFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLV 7094
+FD++KF L+L+ T V++LK Q D++ +L+ G+L++R+ +SD V
Sbjct 466 IFDVAKFDLRLKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 518
>sp|P36697|R1AB_CVCAI Replicase polyprotein 1ab (Fragment) OS=Canine
coronavirus (strain Insavc-1) OX=36391 GN=rep PE=4 SV=1
Length=168
Score = 183 bits (465), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 88/166 (53%), Positives = 119/166 (72%), Gaps = 2/166 (1%)
Query 6932 PKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAF 6991
P TK++ EN SK+GFFTY+ GFI++KL+LGGS AIKITE SWN DLY+L+ F +WT F
Sbjct 1 PNTKSIDGENTSKDGFFTYVNGFIKEKLSLGGSAAIKITEFSWNKDLYELIQRFEYWTVF 60
Query 6992 VTNVNASSSEAFLIGCNYLGK--PREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFP 7049
T+VN SSSE FLIG NYLG R +DG +MHANYIFWRN+ + LS S+ D KF
Sbjct 61 CTSVNTSSSEGFLIGVNYLGPYCDRAIVDGNIMHANYIFWRNSTIMALSHNSVLDTPKFK 120
Query 7050 LKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
+ +++LKE ++N+M++ LL KG+L+IR N +++ + LVN
Sbjct 121 CRCNNALIVNLKEKELNEMVIGLLKKGKLLIRNNGKLLNFGNHLVN 166
>sp|Q04158|R1AB_CVPR8 Replicase polyprotein 1ab (Fragment) OS=Porcine
respiratory coronavirus (strain 86/137004 / isolate
British) OX=33736 GN=rep PE=4 SV=1
Length=131
Score = 127 bits (320), Expect = 3e-32, Method: Composition-based stats.
Identities = 60/129 (47%), Positives = 86/129 (67%), Gaps = 2/129 (2%)
Query 6969 ITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGK--PREQIDGYVMHANY 7026
ITE SWN LY+L+ F +WT F T+VN SSSE FLIG NYLG + +DG +MHANY
Sbjct 1 ITEFSWNKYLYELIQRFEYWTVFCTSVNTSSSEGFLIGVNYLGPYCDKAIVDGNIMHANY 60
Query 7027 IFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRV 7086
IFWRN+ + LS S+ D KF + +++LKE ++N+M++ LL KG+L+IR N ++
Sbjct 61 IFWRNSTIMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVIGLLRKGKLLIRNNGKL 120
Query 7087 VISSDVLVN 7095
+ + +N
Sbjct 121 LNFGNHFIN 129
>sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11156
GN=rep PE=1 SV=1
Length=6857
Score = 137 bits (346), Expect = 4e-30, Method: Compositional matrix adjust.
Identities = 140/581 (24%), Positives = 248/581 (43%), Gaps = 60/581 (10%)
Query 4811 FYDFAVSKGFFKEGSSV--ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVV 4868
FYD + + G K+F++ + A++D YY Y + L V + +
Sbjct 4909 FYDVGLCQELTDAGVDCGEAFKYFYYLSNPAGALADVCYYDYQGTGFYSPKLLAGVYDFM 4968
Query 4869 DKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWG-KARLYYDSMSYEDQDALFAYTKRNV 4927
+ +CY IN + + N G + Y ++ E+ LF Y ++
Sbjct 4969 KRVTECYR---INERFTYEQAKPRKSSMGINITGYQQDAVYRALGPENIARLFEYAQKAP 5025
Query 4928 IPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKL---LKSIAATRGATVVIGTS 4984
+P T++ K+A+SAK RARTV+ S ++ R H+ + + +A G +IG S
Sbjct 5026 LPFCTKIITKFALSAKARARTVSSCSFIASTIFRFAHKPVTSKMVEVAQNSGGFCLIGVS 5085
Query 4985 KFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRF 5044
K+ + LK Y +E + G DY KCDR P R + + +L +
Sbjct 5086 KYGLKFSKFLKDKYGAIEGFDVFGSDYTKCDRTFPLSFRALTAALLYE----LGEWDEKS 5141
Query 5045 YRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLS--T 5102
+ NE + + ++C G L KPGGTSSGDATTA++N+ +N +LS +
Sbjct 5142 WLYLNEVNSYMLDTMLCDGMLLNKPGGTSSGDATTAHSNTFYNYMVHYVVAFKTILSDLS 5201
Query 5103 DGNKIADKYVRNL----QHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCF 5158
+GNK+ N ++++ L ++ F+N LSDD+ + F
Sbjct 5202 EGNKVMRIAAHNAYTTGDYQVFNTLLEDQFQTNYFLN-------------FLSDDSFI-F 5247
Query 5159 NSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGP-HEFCSQHTMLVKQGDD 5217
+ A + + + +NF + L + + + K W+ TKG EFCS H ++K +
Sbjct 5248 SKPEALK--IFTCENFSNKLQTILHTKVDQTKSWS----TKGHIEEFCSAH--IIKTDGE 5299
Query 5218 YVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYL 5277
Y +L P R+L + +D + D M RFV++ ++ +++ + + +F ++L
Sbjct 5300 YHFL--PSRGRLLASLLILDKLSDVDIYYM--RFVAILCESAVYSRYQPEFFNGLFQVFL 5355
Query 5278 QYIRKLH-----DELTGHML--DMYSVMLTNDNTSR-----YWEPEFYEAMYTPHTVLQA 5325
+++ D +L + Y ++ N+ Y E + +
Sbjct 5356 DKVQQFRKDYCCDPCPPQLLEREFYENLVFTSNSEVGIVDCYLENFKLQCEFKQQANFDK 5415
Query 5326 VGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLV 5366
V C C + C C LC C Y HV+ ++H V
Sbjct 5416 V--CFCCPNPAVSVCEECYVPLPLCAYCYYVHVVISNHSKV 5454
Score = 95.5 bits (236), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 104/375 (28%), Positives = 176/375 (47%), Gaps = 58/375 (15%)
Query 6640 QLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSH--SQL 6697
+LP+T F+ R L + + +LA++ + H+ GDF+ + +
Sbjct 6450 ELPDTLFSTGR-LYNLDHDAAQNFNVKQLAIETMPNNH--------HVFSGDFTEVGTDI 6500
Query 6698 GGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEI 6757
GG+H ++ L +K S IP + VK G + +++D+ + E
Sbjct 6501 GGVHHVVAL-NGYKGS------IIP--NYVKPIATGLINVGRAVKRTTLVDVCANQLYEK 6551
Query 6758 IKSQDLSV-VSKVVKVTIDYTEISFMLWCK-DGHVETFYPK---LQSSQAWQPGVAMPNL 6812
+K Q V VSKV+ V ID+ ++ FM++ + ++TFYP+ ++S W PN+
Sbjct 6552 VKQQLEGVKVSKVIFVNIDFQDVQFMVFANGEDDIQTFYPQKDFVRSYYEW------PNI 6605
Query 6813 YKMQRMLLEKCDLQNYGDSAT-LPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAG 6871
+ DL+NYG + T +P+ + N AKYTQ+C ++ + V N V H GA
Sbjct 6606 LP---QIESHYDLKNYGQNPTFMPQPV--NFAKYTQICTFIQD-HVKVARNALVWHLGAA 6659
Query 6872 SDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYD 6931
G +PG VL + L+ D+ D+ STL+ D + + +LI+SD+Y+
Sbjct 6660 GVDGCSPGDIVLSSFFKE-CLVYSWDIKDY-----STLL-DKHSYDCNFRPNLIVSDIYN 6712
Query 6932 PKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSW-NADLYKLMGHFAWWTA 6990
+ NV++ D +LALGG++ K TE S + L + +F+
Sbjct 6713 -VSSNVSEVLDD-----------CVHRLALGGTIVFKTTESSRPDIQLSQFTKYFSAVQF 6760
Query 6991 FVTNVNASSSEAFLI 7005
F VN SSSE F++
Sbjct 6761 FTAGVNTSSSEVFVV 6775
Score = 65.5 bits (158), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 48/147 (33%), Positives = 77/147 (52%), Gaps = 14/147 (10%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAK--HC 1114
VVN AN LKHGGG+A ++ +Q S++YI N + V + G L K +
Sbjct 1715 VVNPANSQLKHGGGIAKVISCMCGPKLQAWSNNYITKNKTVPVTKAIKSPGFQLGKKVNI 1774
Query 1115 LHVVGPNVNKGEDIQLLKSAYENF-----NQHEVLLAPLLSAGIFGADPIHSLRVCVDTV 1169
+H VGP V+ G+ Q L A+ + +QH +L + +LS GIFG ++ +T
Sbjct 1775 IHAVGPRVSDGDVFQKLDQAWRSVFDLCEDQHTILTS-MLSTGIFGC----TVNDSFNTF 1829
Query 1170 RTNVYLAVFDKNLYDKLVSSFLEMKSE 1196
+NV A DK+L +V++ +E ++
Sbjct 1830 LSNV--ARLDKSLVVFVVTNMVEQYNQ 1854
Score = 48.1 bits (113), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 36/103 (35%), Positives = 53/103 (51%), Gaps = 11/103 (11%)
Query 6108 FVLWAHGFELTSMKYFVKIGPERTC--CLCDRRATCFSTASDTYACWHHSIGF--DYVYN 6163
F+L++ +L S+K++V+ TC C C A C + Y C + G + N
Sbjct 6077 FILYSCSNDLKSLKFYVEFD---TCYFCSCGEMAICLMRDGN-YKCRNCYGGMLISKLVN 6132
Query 6164 PFMIDVQQWGFTGNLQSNHDLYCQ-VHGNAHVASCDAIMTRCL 6205
+DVQ+ LQ HD CQ HG++H A CDA+MT+CL
Sbjct 6133 CKYLDVQKERV--KLQDAHDAICQQFHGDSHEALCDAVMTKCL 6173
Score = 46.6 bits (109), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 48/178 (27%), Positives = 78/178 (44%), Gaps = 19/178 (11%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSA--RIVYTACSHAAVDALCEKALKYLPIDKCSRIIPAR 5661
+ GPPGTGK+ F L S+ R VY A +H V + EK +D +
Sbjct 5665 VMGPPGTGKTTFVYDTYLSKASSSNRFVYCAPTHRLVGDMDEK------VDGAVVVSAYN 5718
Query 5662 ARVECFDKFKVNSTLEQY--VFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5719
R + V + + Y + CT N LP + +++ DE+S+ + + + + K
Sbjct 5719 DRTY---RNPVWNKDDSYGVLLCTHNTLPFIKSAVLIADEVSLIPPHVMIKI-LSMGFKK 5774
Query 5720 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVS 5777
V +GDP QL +P K + + F L++ +L C RCP +I+ S
Sbjct 5775 VVLLGDPFQL-SPVYKNHKVHFKYDTF----YLLQLATQKRYLTACYRCPPQILSAFS 5827
Score = 45.4 bits (106), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 36/143 (25%), Positives = 69/143 (48%), Gaps = 17/143 (12%)
Query 3052 IVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLF-------LMSFTVLCLTPVYSFLPGV 3104
V IVV + + R YS+ F ++F +M V+CL P+ +PGV
Sbjct 3063 FVFIVVIFTVIFLILIRLYIVMYSYFKVFTYVVFKLLFVNIIMVLFVVCLPPL---VPGV 3119
Query 3105 YSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRR 3164
V L +L + V FL ++ ++ +F ++P++ + ++ + F+W +
Sbjct 3120 VFV----LALWLCDSVMFLLYLAFLSLF--ILPWFYVLFFLFMVGGFVFWWMMRSADVVH 3173
Query 3165 VVFNGVSFS-TFEEAALCTFLLN 3186
+ +G++F+ TFE+ + C F LN
Sbjct 3174 LTTDGLTFNGTFEQISKCVFPLN 3196
Score = 43.1 bits (100), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 33/107 (31%), Positives = 51/107 (48%), Gaps = 15/107 (14%)
Query 4508 RQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVY 4567
R +++++ DLVYA+ G+ D L E +N D++ + + F+
Sbjct 4662 RGPTSQWSLGDLVYAIWL---GDQDYLSECGFVFNPSRDEFLDDANQRSFL--------- 4709
Query 4568 ANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDF 4614
ANL E A+L ++ + LTLDN DLNG YDFGD+
Sbjct 4710 ANLLE---PAILNFSHIYWQVKMCKVPYKLTLDNVDLNGQLYDFGDY 4753
>sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream
virus (isolate Blicca bjoerkna L./Germany/DF24/00) OX=766180
GN=rep PE=1 SV=1
Length=6872
Score = 133 bits (334), Expect = 1e-28, Method: Compositional matrix adjust.
Identities = 152/653 (23%), Positives = 267/653 (41%), Gaps = 104/653 (16%)
Query 4807 FNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNA--AISDYDYYRYNLPTMCDIRQLLFV 4864
+ + FYD + + G ++ + Q G A+ D+ YY YN P D L V
Sbjct 4888 YKRPFYDLDLIQRMNSAGLNLSETTGYHYQCGTTTEAVEDFMYYNYNSPKSFDPSYLKSV 4947
Query 4865 VEVV-DKYFDCYDGGCINANQVIVNNLDKSAGFP-FNKWGKA------RLYYDSMSYEDQ 4916
+ DK+ I+ ++ L+ +G P + G + ++++ +
Sbjct 4948 YTYMRDKFMKI-----ISTDE----KLNHQSGAPRMSSMGVGVSGFFQKTVWNALPEDFS 4998
Query 4917 DALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRG 4976
L + V+P T + K+ K R RT+ G S ++ R H+ + + T
Sbjct 4999 PRLLDTASKTVMPFSTNIVKKFQRQKKTRVRTLGGSSFITSSIFRMLHKPVTNKMVQTAQ 5058
Query 4977 ATV---VIGTSKFYGGWHNMLKTVYSD-VENPHLMGWDYPKCDRAMPNMLRIM-ASLVLA 5031
A + +IG SKF G+H L + + +E+ +MG DY KCDR+ P + R + A+L
Sbjct 5059 ANIGPFLIGISKFNLGFHKYLSAHHPNGIEDCQVMGADYTKCDRSFPVVCRALSAALFYE 5118
Query 5032 RKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQA 5091
H L + NE L + G ++ KPGGT+SGD+TTA++NS +N
Sbjct 5119 LGH-----LEPNNHWFLNEMFAFLLDPSFISGHIFNKPGGTTSGDSTTAFSNSFYNYFVH 5173
Query 5092 VTANVNALLSTDGNKIADKYVRNLQHRLYEC-------LYRNRDVDTDFVNEFYAYLRKH 5144
+ L+T+ + + + NL H+ + LY + D + F H
Sbjct 5174 LYIQYLTFLTTEMPP-SYQPLCNLAHQAFSTGNTETYDLYFSMADDLNSTEYFL-----H 5227
Query 5145 FSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEF 5204
F LSDD+ + T + + NF L ++ AK W+ HEF
Sbjct 5228 F----LSDDSFIISKPTAFP---IFTPANFSMKLQNVLGCYVDPAKSWSADGEI---HEF 5277
Query 5205 CSQHTMLVKQGDDYVYLPYPDPSRIL-GAGC---------FVDDIVKTDGTLMIERFVSL 5254
CS H + + YV PDP+ +L G C + +V T L + FV+
Sbjct 5278 CSSHICKINEKYQYV----PDPNNMLAGLICAPEPTPQDKLIWKLVATCAELAVFHFVNP 5333
Query 5255 AIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHM-----------LDMYSVMLTNDN 5303
+ + ++FHL ++ LH E +D Y+ ++ +++
Sbjct 5334 TL------------FNNIFHL----LQSLHAEFVSEHSVNLLPPKLLEIDFYTDLIDSED 5377
Query 5304 TSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSH 5363
+Y + + + ++Q+ C C++ T C C + +C C Y+H++ T H
Sbjct 5378 VEQY--SFLADTLTEKNIIMQSASQCYFCDNATVSTCSDCTVQYPMCAHCAYEHLMLTDH 5435
Query 5364 KLVLSVNPYVCNAPGCDVTDVTQL----YLGGMSYYCKSHKPPISFPLCANGQ 5412
+ +V CD TD L +G + C +H ++ PL + +
Sbjct 5436 TPTQVLPCHV-----CDQTDPRHLNHTFVMGTVKVACDNHVEGMALPLVDHAR 5483
Score = 82.0 bits (201), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 89/341 (26%), Positives = 144/341 (42%), Gaps = 50/341 (15%)
Query 6685 EHIVYGDFSHSQ--LGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKC 6742
H+ GD S+ +GG+H+L + ++L P + ++ I A +K
Sbjct 6496 HHVSVGDTSNVSWTIGGMHVLTAFQNI---TNYQLVSG-PANPIMR---INVALERGNKV 6548
Query 6743 VCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCK-DGHVETFYPKLQSS- 6800
+ +D L D+ +I + ++V SK T+D + M + DG ++T YP Q+
Sbjct 6549 ETTALDTTLQDYYKIATTNKVTV-SKTTFFTLDGGQYRMMNFANPDGTIQTSYPVAQAQS 6607
Query 6801 ------QAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIM--MNVAKYTQLCQYL 6852
+ + + P + E D + PK +N+ KY Q+C L
Sbjct 6608 QLITNYRIYPSYITWPTFFTN-----EATDCWAIPNYNAPPKNQTCNINIQKYDQMCD-L 6661
Query 6853 NTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGD 6912
+ L +P + H G +K +PG VLRQ+ L DL + VSD
Sbjct 6662 FAIDLKIPVKGHIHHLGNAGNK-YSPGDVVLRQYFDQAHL-TSYDLREVVSD-------- 6711
Query 6913 CATVHTANKWD--LIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKIT 6970
+H ++W I+SD+Y P T F + ++Q L LGGS+ K+T
Sbjct 6712 IPVLHPNDEWKAHFILSDVYAPDT-----------DFTSLALEYMQNHLRLGGSIMWKMT 6760
Query 6971 EHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLG 7011
E S + +++ +F W A VN SSSE FL Y G
Sbjct 6761 ETSI-LQVNEIVKYFGSWKAVTFAVNYSSSETFLFCAGYTG 6800
Score = 63.9 bits (154), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 81/320 (25%), Positives = 121/320 (38%), Gaps = 60/320 (19%)
Query 4307 AITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLK 4366
AI+ P + ++ G S C C DH C G +VQIP ++ F L
Sbjct 4468 AISQVPVQTIGYLTYAGISVCRQCATKQDHT-----CQYAGYFVQIPREHVSN--IFNLT 4520
Query 4367 NTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLT----PCGTG---TS 4419
+T C K +C L++ QS Q LN V L P TG S
Sbjct 4521 DT--PPCLHNKFTCTTCQPLQQ---QSKTQQPPLNLVGQCLGLTLDTAFCPFQTGEYKPS 4575
Query 4420 TDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKD-----EDDNLIDSYFVVKRHTFSNYQH 4474
+ Y +I N+ VA K K N ++ +D +V K+
Sbjct 4576 SREFY--INILNNNVASLRKVFKKNTASIPSENGTIMLKDTGTAHEIYVAKQ-------- 4625
Query 4475 EETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTL 4534
LL V +H R + D ++ R T Y++ DLVYA D
Sbjct 4626 ------LLAKGLPVLQHA----RFNHDGTDYLIRYYTTPYSLGDLVYAYMVGD------F 4669
Query 4535 KEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIV 4594
K +L+ + D+ + ++ Y N E++R L + + + A +
Sbjct 4670 KHMLLALDITDETCLDPGNYSS----------YYNFKEQLRNKLASVIPNVNKILAAELP 4719
Query 4595 GVLTLDNQDLNGNWYDFGDF 4614
+TLDN DLNG YDFGD+
Sbjct 4720 LAITLDNIDLNGFLYDFGDY 4739
Score = 50.8 bits (120), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 66/302 (22%), Positives = 126/302 (42%), Gaps = 25/302 (8%)
Query 5598 MQKYSTLQGPPGTGKSHFAIG--LALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS 5655
++K + + GPPGTGK+ + + + P+ ++ Y A +H V ++ +
Sbjct 5641 LKKATFIIGPPGTGKTTYVMKNFIDTASPANKVAYIAPTHKLVQSMDQAIWDKYNHTVSV 5700
Query 5656 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5715
++ + ++ + +NS + + T A+ ++FDE++++ + + +
Sbjct 5701 SVVKSELNNNKYN-YPLNSATKTIMLGTPGAVCTHAGCTLIFDEVTLSQLNTIINAISVV 5759
Query 5716 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5775
+ +++GDP QL P T + +L Y N L + L C RCP+ I
Sbjct 5760 KPSQVIFLGDPLQL-GPVTHM--RSLSYSYTN--FPLFQFCNDSRVLSICYRCPSNI--- 5811
Query 5776 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVF 5835
++ +K + D + + G VS + P + L RN + V
Sbjct 5812 -----FNLWVKPYTDSNVRIDPHAAGGDAKIIVSDQCSNPDAYQYVQKLARNNPDK--VL 5864
Query 5836 ISPYNSQNAVASKILGLPTQ-TVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKV 5894
+ Y I+GL T+DSSQG Y + I T + +NR VA++R+
Sbjct 5865 LCNYKK------PIIGLENAVTIDSSQGKTYKHTIVVLLGNTNFTQVINRAIVAMSRSTH 5918
Query 5895 GI 5896
I
Sbjct 5919 SI 5920
Score = 50.4 bits (119), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 37/110 (34%), Positives = 54/110 (49%), Gaps = 8/110 (7%)
Query 6104 DRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYA--CWHHS---IGF 6158
+RVV+VL+ G +L ++ +G + TC C + AT ++ + C HH+
Sbjct 6074 NRVVYVLYGAGNDLRALTNLNIVG-DYTCEKCTKEATFYTIHREIVHTFCNHHAPSQFPL 6132
Query 6159 DYVYNPFMIDVQQWGFTG-NLQSNHDLYC-QVHGNAHVASCDAIMTRCLA 6206
N ID+Q +L + H C Q HG+AH AS D IMT CLA
Sbjct 6133 MGTINAQAIDIQHASANKQSLTNTHAEVCNQQHGDAHTASADTIMTGCLA 6182
>sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus
1 OX=360393 GN=rep PE=2 SV=1
Length=6733
Score = 127 bits (320), Expect = 4e-27, Method: Compositional matrix adjust.
Identities = 135/555 (24%), Positives = 231/555 (42%), Gaps = 52/555 (9%)
Query 4829 LKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVN 4888
K+F++ + A++D +Y Y + L V + + + CY +
Sbjct 4805 FKYFYYLSNPAGALADVCFYDYQGTGFYSPKLLAGVYDFMKRVTTCYK---TDERFTYEQ 4861
Query 4889 NLDKSAGFPFNKWG-KARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRAR 4947
+ + N G + Y ++ E+ LF Y ++ +P T++ K+A+SAK RAR
Sbjct 4862 AKPRKSSMGINITGYQQDAVYRALGPENITKLFEYAQKAPLPFCTKIITKFALSAKARAR 4921
Query 4948 TVAGVSICSTMTNRQFHQKL---LKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENP 5004
TV+ S ++ R H+ + + +A +IG SK+ + LK Y +E
Sbjct 4922 TVSSCSFIASTIFRFAHKPVTSKMVEVAQNSQGFCLIGVSKYGLKFSKFLKDKYGAIEQF 4981
Query 5005 HLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGS 5064
+ G DY KCDR P R + + +L + NE + + ++C G
Sbjct 4982 DVFGSDYTKCDRTFPLSFRALTAALLYELG----GWEEDSWLYLNEVNSYMLDTMLCDGM 5037
Query 5065 LYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLS--TDGNKIADKYVRNLQHRLYEC 5122
L KPGGTSSGDATTA++N+ +N +LS +D NK+ +R H Y
Sbjct 5038 LLNKPGGTSSGDATTAHSNTFYNYMVHYVVAFKTILSDLSDCNKV----MRIAAHNAYT- 5092
Query 5123 LYRNRDVDTDFVNEFYAYLRKHFS----MMILSDDAVVCFNSTYASQGLVASIKNFKSVL 5178
T F L + F + LSDD+ + F+ A + + + +NF + L
Sbjct 5093 --------TGDYGVFNTLLEEQFQTNYFLNFLSDDSFI-FSKPGALK--IFTCENFSNKL 5141
Query 5179 YYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDD 5238
+ + K W T + EFCS H ++K +Y +L P R+L + +D
Sbjct 5142 QTILHTKVDLTKSWATTGHIE---EFCSAH--IIKTDGEYHFL--PSRGRLLASLLILDK 5194
Query 5239 IVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLH-----DELTGHMLD 5293
+ D M RFV++ ++ +++ + + +F ++L +++ D +LD
Sbjct 5195 LSDVDIYYM--RFVAILCESAVYSRYQPEFFNGLFQVFLDKVQQFRKDYCCDPCPTQLLD 5252
Query 5294 --MYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVG---ACVLCNSQTSLRCGACIRRPF 5348
Y ++ NT + E Q G C C + C C
Sbjct 5253 RQFYENLVFTSNTEVGLVDCYLENFKLQCEFKQQAGFDRVCFCCPNPAVSVCEECYVPLP 5312
Query 5349 LCCKCCYDHVISTSH 5363
LC C Y HV+ +SH
Sbjct 5313 LCAYCYYVHVVISSH 5327
Score = 98.6 bits (244), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 118/407 (29%), Positives = 191/407 (47%), Gaps = 72/407 (18%)
Query 6616 GVTLIGEAVKTQFNYYKKVDG--VVQQLPETYFTQSR--NLQEFKPRSQMEIDFLELAMD 6671
V + EA Q YY ++ +++LPET F+ R NL E P + +LA++
Sbjct 6300 SVHIYVEATGEQPLYYLQLGNGESLRELPETLFSTGRLYNL-EHDPSKNFNVQ--QLAIE 6356
Query 6672 EFIERYKLEGYAFEHIVYGDFSH--SQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKN 6729
+ + H+ GDF+ + +GG+H ++ L +K S IP + VK
Sbjct 6357 TIPKNH--------HVFAGDFTDVGTDIGGVHHVVAL-NGYKGS------IIP--NYVKP 6399
Query 6730 YFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV-VSKVVKVTIDYTEISFMLWCK-D 6787
G S +++D+ + E +K Q V VSKV+ V ID+ E+ FM++ K +
Sbjct 6400 IATGLINVGRSVKRTTLVDVCANQLYEKVKQQIAGVKVSKVIFVNIDFQEVQFMVFAKGE 6459
Query 6788 GHVETFYPK---LQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYG-DSATLPKGIMMNVA 6843
++TFYP+ ++S W P + +P L DL+NYG D +P+ + N A
Sbjct 6460 DDIQTFYPQKEFIRSYYEW-PTI-LPELESHY-------DLKNYGQDPQFMPQPV--NFA 6508
Query 6844 KYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVS 6903
KYTQ+C ++ + V N + H GA G +PG VL + L+ D+ D+
Sbjct 6509 KYTQICTFIQE-HVKVARNSLIWHVGAAGIDGCSPGDIVLSSFFKE-CLVYSWDVKDY-- 6564
Query 6904 DADSTLIG----DCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKL 6959
TL+ DC + +LI+SD+Y+ + NV++ + +L
Sbjct 6565 ---DTLLEKHNYDCNF-----RPNLIVSDVYN-VSSNVSEVLED-----------CVHRL 6604
Query 6960 ALGGSVAIKITEHSW-NADLYKLMGHFAWWTAFVTNVNASSSEAFLI 7005
ALGG++ K TE S + L K+ +FA F VN SSSE F++
Sbjct 6605 ALGGTIIFKTTESSRPDIQLSKVTKYFAAVHFFTAGVNTSSSEVFVV 6651
Score = 53.5 bits (127), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 35/105 (33%), Positives = 50/105 (48%), Gaps = 6/105 (6%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAK--HC 1114
VVN AN LKHGGG+A ++ + S++YI L V + G L K
Sbjct 1669 VVNPANNQLKHGGGIAKVISCMCGPKLTSWSNNYIKQYKKLGVTCAIRSPGFQLGKGVQI 1728
Query 1115 LHVVGPNVNKGEDIQLL----KSAYENFNQHEVLLAPLLSAGIFG 1155
+HVVGP + + L +S ++N +L +LS GIFG
Sbjct 1729 IHVVGPKSADSDVVNKLEASWRSVFQNVKPDTTVLTSMLSTGIFG 1773
Score = 52.0 bits (123), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 48/176 (27%), Positives = 79/176 (45%), Gaps = 15/176 (9%)
Query 5604 LQGPPGTGKSHFAIG--LALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPAR 5661
+ GPPGTGK+ F L+ PS R VY A +H V + EK +D +
Sbjct 5541 VMGPPGTGKTTFVYNTYLSKASPSNRFVYCAPTHRLVGDMDEK------VDGAVVVSAYN 5594
Query 5662 ARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYV 5721
R +K + + + + CT N LP + +++ DE+S+ + + + + K V
Sbjct 5595 DRTYRNPVWKKDDSYD-VLLCTHNTLPFIKSAVLIVDEVSLIPPHVMIKI-LSMGFKKVV 5652
Query 5722 YIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVS 5777
+GDP QL +P K + + F L++ +L C RCP +I+ S
Sbjct 5653 LLGDPFQL-SPVYKNHKVHFKYDTF----YLLQLATQKRYLTACYRCPPQILSAFS 5703
Score = 50.8 bits (120), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 34/101 (34%), Positives = 52/101 (51%), Gaps = 7/101 (7%)
Query 6108 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYAC--WHHSIGFDYVYNPF 6165
F+L++ +L S+K++V+ G C C A C Y C + ++ + N
Sbjct 5953 FILYSCSNDLKSLKFYVEFGTNYFCS-CGELAICL-MRDGLYKCRNCYGNMSISKLVNCK 6010
Query 6166 MIDVQQWGFTGNLQSNHDLYCQ-VHGNAHVASCDAIMTRCL 6205
+DVQ+ LQ HD CQ HG++H A CDA+MT+CL
Sbjct 6011 YLDVQKERI--KLQDAHDAICQQFHGDSHEALCDAVMTKCL 6049
Score = 44.3 bits (103), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 40/154 (26%), Positives = 76/154 (49%), Gaps = 15/154 (10%)
Query 3047 IVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL---MSFTVLCLTPVYSFLPG 3103
+V I IV L ++ F +++VV LLF+ M V+CL P+ +PG
Sbjct 2944 VVLVAIFTIVFLFLLRMYIVMYSYFKVFTYVVF--KLLFVNTVMVLFVVCLPPL---VPG 2998
Query 3104 VYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKR 3163
V V L +L + V FL ++ + +F ++P++ + +++ + F+W +
Sbjct 2999 VVFV----LALWLCDSVVFLLYLAVLSLF--ILPWFYVMLFVLIVGGFVFWWMMKSSDVV 3052
Query 3164 RVVFNGVSFS-TFEEAALCTFLLNKEMYLKLRSD 3196
+ +G++F+ TFE+ + C F LN + +L D
Sbjct 3053 HLTPDGLTFNGTFEQVSKCVFPLNPLIVNRLLLD 3086
Score = 40.8 bits (94), Expect = 0.67, Method: Compositional matrix adjust.
Identities = 36/133 (27%), Positives = 59/133 (44%), Gaps = 20/133 (15%)
Query 4487 AVAKHDFFKFRIDGDMVPH-----ISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTY 4541
A+A+ F I MV + R T++++ DLVYA+ D+ D E +
Sbjct 4512 ALARTAFLPSIIPHHMVHQNGEWFLVRGPTTQWSLGDLVYAIWLGDQAYLD---ECGFVF 4568
Query 4542 NCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDN 4601
N D++ + + ++ ANL E A+L + ++ + +TLDN
Sbjct 4569 NPSRDEFLDDANQRSYL---------ANLLE---PAILSFCEIFHCVKGCQVPYKITLDN 4616
Query 4602 QDLNGNWYDFGDF 4614
DL G YDFGD+
Sbjct 4617 LDLKGQLYDFGDY 4629
>sp|Q4J9D2|Y1252_SULAC Uncharacterized protein Saci_1252 OS=Sulfolobus
acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929
/ NBRC 15157 / NCIMB 11770) OX=330779 GN=Saci_1252 PE=4
SV=1
Length=181
Score = 73.2 bits (178), Expect = 1e-12, Method: Composition-based stats.
Identities = 45/124 (36%), Positives = 71/124 (57%), Gaps = 10/124 (8%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
V ++N DI KV+ +VNAAN YL HGGGVA A+ ++ +Q ESD+Y+ NGP+
Sbjct 13 VILENGDIT----KVEADAIVNAANSYLSHGGGVALAIVRSGGYIIQEESDEYVRRNGPV 68
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQL---LKSAYENFNQHEV--LLAPLLSA 1151
VG V + L A++ +H VGP D +L ++ + E ++ ++ + P +S
Sbjct 69 PVGEVAVTTAGKLKARYVIHAVGPRYGIEGDDKLESAIRRSLEKADELKLSSIALPAIST 128
Query 1152 GIFG 1155
GI+G
Sbjct 129 GIYG 132
>sp|Q97UU4|Y2899_SACS2 Uncharacterized protein SSO2899 OS=Saccharolobus
solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322
/ P2) OX=273057 GN=SSO2899 PE=4 SV=1
Length=177
Score = 72.8 bits (177), Expect = 2e-12, Method: Composition-based stats.
Identities = 53/167 (32%), Positives = 85/167 (51%), Gaps = 19/167 (11%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
+Y+ DI E ++ +VNAAN YL+HGGGVA A+ + +Q ESD+Y+ GP+
Sbjct 10 IYLIKGDITE----IEADAIVNAANSYLQHGGGVAYAIVRKGGYIIQKESDEYVKKFGPV 65
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVN-KGEDIQLLKSAYENFNQHEVL-----LAPLLS 1150
VG V S L AK+ +H VGP +GED +L + +++ + + L P +S
Sbjct 66 PVGEVAVTSAGKLKAKYVIHAVGPRYGIEGED-KLESAIFKSLLKADELSLSSIAMPAIS 124
Query 1151 AGIFGADPIHSLRVCVDTVR-------TNVYLAVFDKNLYDKLVSSF 1190
GI+G R+ + ++ V + ++ K+ YD S F
Sbjct 125 TGIYGYPFEICARIMANVLKGYKPKTLRKVMICLYTKDAYDVFKSIF 171
>sp|Q8ZXT3|Y1111_PYRAE Uncharacterized protein PAE1111 OS=Pyrobaculum
aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630
/ CIP 104966 / NBRC 100827 / IM2) OX=178306 GN=PAE1111 PE=4
SV=1
Length=182
Score = 72.8 bits (177), Expect = 2e-12, Method: Composition-based stats.
Identities = 55/170 (32%), Positives = 83/170 (49%), Gaps = 23/170 (14%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
V + DI E V+ +VNAAN YL+HGGGVAGA+ + +Q ES +++ +GP+
Sbjct 10 VVLMRGDITE----VEADAIVNAANSYLEHGGGVAGAIVRKGGQVIQEESREWVRKHGPV 65
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYEN--FNQHEVLLA----PLLS 1150
VG V S L AK+ +H VGP E I+ L A +N E+ L P +S
Sbjct 66 PVGDVAVTSAGRLKAKYVIHAVGPRCGV-EPIEKLAEAVKNALLKAEELGLVSIALPAIS 124
Query 1151 AGIFG----------ADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSF 1190
GIFG A I + + ++R + + ++ + Y K + F
Sbjct 125 TGIFGCPYDAAAEQMATAIREVAPALRSIR-RILVVLYGEEAYQKFLEVF 173
>sp|Q9WYX8|Y508_THEMA Uncharacterized protein TM_0508 OS=Thermotoga
maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC
100826 / MSB8) OX=243274 GN=TM_0508 PE=3 SV=1
Length=599
Score = 76.3 bits (186), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 51/128 (40%), Positives = 67/128 (52%), Gaps = 13/128 (10%)
Query 1037 NVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGP 1096
+ I DI E + +VNAAN YLKHGGGVAGA+ +A + +Q ESD + G
Sbjct 428 KIRIVKGDITRE----EVDAIVNAANEYLKHGGGVAGAIVRAGGSVIQEESDRIVQERGR 483
Query 1097 LKVGGSCVLSGHNL-AKHCLHVVGP---NVNKGEDIQLLKSAYEN-FNQHEVLLA----P 1147
+ G + V S L AK+ +H VGP + GED L K+ Y HE+ L P
Sbjct 484 VPTGEAVVTSAGKLKAKYVIHTVGPVWRGGSHGEDELLYKAVYNALLRAHELKLKSISMP 543
Query 1148 LLSAGIFG 1155
+S GIFG
Sbjct 544 AISTGIFG 551
>sp|Q96XY5|Y2383_SULTO Uncharacterized protein STK_23830 OS=Sulfurisphaera
tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140
/ 7) OX=273063 GN=STK_23830 PE=4 SV=1
Length=182
Score = 67.0 bits (162), Expect = 2e-10, Method: Composition-based stats.
Identities = 58/189 (31%), Positives = 93/189 (49%), Gaps = 32/189 (17%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
V I DI E ++ +VNAAN YL+HGGGVA A+ + +Q ES +Y+ GP+
Sbjct 3 VKIIKGDITE----IEAEAIVNAANSYLEHGGGVARAIVEKGGYIIQKESREYVRKYGPV 58
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVN-KGEDIQLLKSAYENF--NQHEVLLA----PLL 1149
GG V S L AK+ +H VGP +GE + L+ A N E+ L+ P +
Sbjct 59 PTGGVAVTSAGKLKAKYVIHAVGPRYGIEGE--EKLEEAIRNALRKAEELKLSSIALPAI 116
Query 1150 SAGIFGADPIHSLRVCVDTV-------RTN------VYLAVFDKNLYDKLVSSF-LEMKS 1195
S GI+G + +C + + TN + ++++ + Y+ V+ F E+
Sbjct 117 STGIYG----YPYEICAEKMVKVIKEEYTNFKHLNTIIVSLYSEEAYNIFVNIFERELAK 172
Query 1196 EKQVEQKIA 1204
EK + K++
Sbjct 173 EKNITLKMS 181
>sp|P0C6F3|R1A_BEV Replicase polyprotein 1a OS=Berne virus OX=11156
GN=1a PE=1 SV=1
Length=4569
Score = 65.5 bits (158), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 48/147 (33%), Positives = 77/147 (52%), Gaps = 14/147 (10%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAK--HC 1114
VVN AN LKHGGG+A ++ +Q S++YI N + V + G L K +
Sbjct 1715 VVNPANSQLKHGGGIAKVISCMCGPKLQAWSNNYITKNKTVPVTKAIKSPGFQLGKKVNI 1774
Query 1115 LHVVGPNVNKGEDIQLLKSAYENF-----NQHEVLLAPLLSAGIFGADPIHSLRVCVDTV 1169
+H VGP V+ G+ Q L A+ + +QH +L + +LS GIFG ++ +T
Sbjct 1775 IHAVGPRVSDGDVFQKLDQAWRSVFDLCEDQHTILTS-MLSTGIFGC----TVNDSFNTF 1829
Query 1170 RTNVYLAVFDKNLYDKLVSSFLEMKSE 1196
+NV A DK+L +V++ +E ++
Sbjct 1830 LSNV--ARLDKSLVVFVVTNMVEQYNQ 1854
Score = 45.4 bits (106), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 36/143 (25%), Positives = 69/143 (48%), Gaps = 17/143 (12%)
Query 3052 IVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLF-------LMSFTVLCLTPVYSFLPGV 3104
V IVV + + R YS+ F ++F +M V+CL P+ +PGV
Sbjct 3063 FVFIVVIFTVIFLILIRLYIVMYSYFKVFTYVVFKLLFVNIIMVLFVVCLPPL---VPGV 3119
Query 3105 YSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRR 3164
V L +L + V FL ++ ++ +F ++P++ + ++ + F+W +
Sbjct 3120 VFV----LALWLCDSVMFLLYLAFLSLF--ILPWFYVLFFLFMVGGFVFWWMMRSADVVH 3173
Query 3165 VVFNGVSFS-TFEEAALCTFLLN 3186
+ +G++F+ TFE+ + C F LN
Sbjct 3174 LTTDGLTFNGTFEQISKCVFPLN 3196
>sp|P36327|POLN_EEVV3 Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain 3880) OX=36382 PE=3 SV=3
Length=2485
Score = 63.2 bits (152), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 47/141 (33%), Positives = 70/141 (50%), Gaps = 26/141 (18%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCL 1115
V++NAAN + GGGV GAL K + ++ P++VG + ++ G AKH +
Sbjct 1347 VIINAANSKGQPGGGVCGALYKKFPESFDLQ---------PIEVGKARLVKG--AAKHII 1395
Query 1116 HVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVLLAPLLSAGIFGAD------PIH 1160
H VGPN NK +I+ L AYE N N ++ + PLLS GIF + ++
Sbjct 1396 HAVGPNFNKVSEIEGDKQLAEAYESIAKIVNDNNYKSVAIPLLSTGIFSGNKDRLTQSLN 1455
Query 1161 SLRVCVDTVRTNVYLAVFDKN 1181
L +DT +V + DK
Sbjct 1456 HLLTALDTTDADVAIYCRDKK 1476
>sp|Q8CAS9|PARP9_MOUSE Protein mono-ADP-ribosyltransferase PARP9
OS=Mus musculus OX=10090 GN=Parp9 PE=1 SV=2
Length=866
Score = 62.8 bits (151), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 48/142 (34%), Positives = 64/142 (45%), Gaps = 16/142 (11%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKH-CL 1115
VVNAAN L HG G+AG+L K +Q ES IA G + VGG + L H +
Sbjct 137 VVNAANENLLHGSGLAGSLVKTGGFEIQEESKRIIANVGKISVGGIAITGAGRLPCHLII 196
Query 1116 HVVGPN---VNKGEDIQLLKSAYENFNQH--------EVLLAPLLSAGIFGADPIHSLRV 1164
H VGP N I+LLK A N + + + P LS+GIF L +
Sbjct 197 HAVGPRWTVTNSQTAIELLKFAIRNILDYVTKYDLRIKTVAIPALSSGIFQ----FPLDL 252
Query 1165 CVDTVRTNVYLAVFDKNLYDKL 1186
C + + L DK ++ L
Sbjct 253 CTSIILETIRLYFQDKQMFGNL 274
>sp|P27282|POLN_EEVVT Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain Trinidad donkey) OX=11038 PE=1 SV=3
Length=2493
Score = 62.4 bits (150), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 46/141 (33%), Positives = 70/141 (50%), Gaps = 26/141 (18%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCL 1115
V++NAAN + GGGV GAL K + ++ P++VG + ++ G AKH +
Sbjct 1347 VIINAANSKGQPGGGVCGALYKKFPESFDLQ---------PIEVGKARLVKG--AAKHII 1395
Query 1116 HVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVLLAPLLSAGIFGAD------PIH 1160
H VGPN NK +++ L AYE N N ++ + PLLS GIF + ++
Sbjct 1396 HAVGPNFNKVSEVEGDKQLAEAYESIAKIVNDNNYKSVAIPLLSTGIFSGNKDRLTQSLN 1455
Query 1161 SLRVCVDTVRTNVYLAVFDKN 1181
L +DT +V + DK
Sbjct 1456 HLLTALDTTDADVAIYCRDKK 1476
>sp|P36328|POLN_EEVVP Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain P676) OX=36385 PE=1 SV=2
Length=2493
Score = 62.4 bits (150), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 46/141 (33%), Positives = 70/141 (50%), Gaps = 26/141 (18%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCL 1115
V++NAAN + GGGV GAL K + ++ P++VG + ++ G AKH +
Sbjct 1347 VIINAANSKGQPGGGVCGALYKKFPESFDLQ---------PIEVGKARLVKG--AAKHII 1395
Query 1116 HVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVLLAPLLSAGIFGAD------PIH 1160
H VGPN NK +++ L AYE N N ++ + PLLS GIF + ++
Sbjct 1396 HAVGPNFNKVSEVEGDKQLAEAYESIAKIVNDNNYKSVAIPLLSTGIFSGNKDRLTQSLN 1455
Query 1161 SLRVCVDTVRTNVYLAVFDKN 1181
L +DT +V + DK
Sbjct 1456 HLLTALDTTDADVAIYCRDKK 1476
>sp|A7MG20|YMDB_CROS8 O-acetyl-ADP-ribose deacetylase OS=Cronobacter
sakazakii (strain ATCC BAA-894) OX=290339 GN=ymdB PE=3
SV=1
Length=180
Score = 58.2 bits (139), Expect = 2e-07, Method: Composition-based stats.
Identities = 47/158 (30%), Positives = 71/158 (45%), Gaps = 21/158 (13%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHC 1114
V+VNAAN L GGGV GA+++A A+ G + G + + +L AK
Sbjct 19 VIVNAANPSLMGGGGVDGAIHRAAGPALLAACRQVRQQQGECQPGHAVITEAGDLAAKAV 78
Query 1115 LHVVGPNVNKGED--IQLLKSAYEN------FNQHEVLLAPLLSAGIFGADPIHSLRVCV 1166
+H VGP G+D QLL AY N N + + P +S GI+G + ++
Sbjct 79 VHTVGPVWRGGQDNEPQLLADAYRNSLQLVAANGYNSVAFPAISTGIYGYPKAAAAQIAF 138
Query 1167 DTVR---------TNVYLAVFDKN---LYDKLVSSFLE 1192
+TV VY +D+ LY +L+ + E
Sbjct 139 ETVSDYLTRHPQPKQVYFVCYDEENFLLYQRLLGQYDE 176
>sp|E1SDF1|YMDB1_PANVC O-acetyl-ADP-ribose deacetylase 1 OS=Pantoea
vagans (strain C9-1) OX=712898 GN=ymdB1 PE=3 SV=1
Length=171
Score = 57.0 bits (136), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 46/152 (30%), Positives = 71/152 (47%), Gaps = 18/152 (12%)
Query 1051 KVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL 1110
KV +VNAAN L GGGV GA+++A + E G KVG + + NL
Sbjct 13 KVSAEAIVNAANSSLLGGGGVDGAIHRAGGPVILAECQLIRNRQGGCKVGDAVITGAGNL 72
Query 1111 -AKHCLHVVGPNVNKG--EDIQLLKSAYE------NFNQHEVLLAPLLSAGIFGADPIHS 1161
A + +H VGP + G ++ LLK AY+ +++ + + P +S GI+G +
Sbjct 73 PADYVIHTVGPRWSDGRHDEDALLKRAYQSCFKLVDYHGIKTVSFPNISTGIYGFPKERA 132
Query 1162 LRVCVDTVR---------TNVYLAVFDKNLYD 1184
+ +D ++ NV L FD YD
Sbjct 133 ATIALDVIKHCIAENRTLENVNLVCFDAENYD 164
>sp|A8AI35|YMDB_CITK8 O-acetyl-ADP-ribose deacetylase OS=Citrobacter
koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
OX=290338 GN=ymdB PE=3 SV=1
Length=177
Score = 56.6 bits (135), Expect = 8e-07, Method: Composition-based stats.
Identities = 49/178 (28%), Positives = 84/178 (47%), Gaps = 29/178 (16%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++++ DI + + V+VNAAN L GGGV GA+++A +
Sbjct 1 MKSRIHVQHGDITQ----LTVDVIVNAANASLLGGGGVDGAIHRAAGPTLLEACKKVRQQ 56
Query 1094 NGPLKVGGSCV-LSGHNLAKHCLHVVGPNVNKGE--DIQLLKSAYENFNQHEVLLA---- 1146
G G + + L+G+ AK +H VGP G+ + QLL+ AY FN +++LA
Sbjct 57 QGECPAGHAVITLAGNLPAKAVIHTVGPVWRGGDHNESQLLEDAY--FNSLQLVLANGYR 114
Query 1147 ----PLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVS 1188
P +S G +G + + V+TV VY +D+ LY++L++
Sbjct 115 SVAFPAISTGAYGYPRPAAAEIAVNTVADFLARHALPEQVYFVCYDEETARLYERLLT 172
>sp|Q8V294|POLN_EEVVC Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain CPA201) OX=376610 PE=3 SV=3
Length=2497
Score = 59.3 bits (142), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 44/141 (31%), Positives = 69/141 (49%), Gaps = 26/141 (18%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCL 1115
V+VNAAN + G GV GAL + + ++ P++VG + ++ G+ +KH +
Sbjct 1347 VIVNAANSKGQPGSGVCGALYRKYPESFDLQ---------PIEVGKARLVKGN--SKHLI 1395
Query 1116 HVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVLLAPLLSAGIFGAD------PIH 1160
H VGPN NK +++ L AYE N N + + PLLS GIF + ++
Sbjct 1396 HAVGPNFNKVSEVEGDKQLAEAYESIARIINDNNYRSVAIPLLSTGIFAGNKDRLMQSLN 1455
Query 1161 SLRVCVDTVRTNVYLAVFDKN 1181
L +DT +V + DK
Sbjct 1456 HLLTALDTTDADVAIYCRDKK 1476
>sp|B6SFA4|MAA3_ARATH Probable helicase MAGATAMA 3 OS=Arabidopsis
thaliana OX=3702 GN=MAA3 PE=2 SV=1
Length=818
Score = 58.9 bits (141), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 68/251 (27%), Positives = 99/251 (39%), Gaps = 47/251 (19%)
Query 5693 DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC-R 5751
D+V+ DE + A +++ R K +GDP QLPA T+++ + Y S+ R
Sbjct 485 DVVIIDEAAQAVE-PATLIPLATRCKQVFLVGDPKQLPA--TVISTVAQDSGYGTSMFER 541
Query 5752 LMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ--------------CFK 5797
L K P L T R EI S Y+ L+ D AQ CF
Sbjct 542 LQKAGYPVKMLKTQYRMHPEIRSFPSKQFYEGALEDGSDIEAQTTRDWHKYRCFGPFCFF 601
Query 5798 MFYKGVITHD---VSSAINRPQIGVV----REFLTRNPAWRKA---VFISPYNSQ----- 5842
++G + S +N ++ V +T P + + ISPYN Q
Sbjct 602 DIHEGKESQHPGATGSRVNLDEVEFVLLIYHRLVTMYPELKSSSQLAIISPYNYQVKTFK 661
Query 5843 -------NAVASKILGLPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAIT 5890
A K++ + TVD QG E D IF+ + + N R NV IT
Sbjct 662 DRFKEMFGTEAEKVVDI--NTVDGFQGREKDVAIFSCVRANENGQIGFLSNSRRMNVGIT 719
Query 5891 RAKVGILCIMS 5901
RAK +L + S
Sbjct 720 RAKSSVLVVGS 730
>sp|C9Y0V8|YMDB_CROTZ O-acetyl-ADP-ribose deacetylase OS=Cronobacter
turicensis (strain DSM 18703 / CCUG 55852 / LMG 23827
/ z3032) OX=693216 GN=ymdB PE=3 SV=1
Length=176
Score = 55.1 bits (131), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 46/163 (28%), Positives = 72/163 (44%), Gaps = 21/163 (13%)
Query 1051 KVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL 1110
++ V+VNAAN L GGGV GA+++A ++ G + G + + +L
Sbjct 14 RIDTDVIVNAANPSLMGGGGVDGAIHRAAGPSLLAACKVVRQQQGECQPGHAVITEAGDL 73
Query 1111 -AKHCLHVVGPNVNKGED--IQLLKSAYEN------FNQHEVLLAPLLSAGIFGADPIHS 1161
AK +H VGP G D QLL AY N N + + P +S GI+G +
Sbjct 74 AAKAVIHTVGPIWRGGHDNEPQLLADAYRNSLELVTANGYNSVAFPAISTGIYGYPKAAA 133
Query 1162 LRVCVDTVR---------TNVYLAVFDKN---LYDKLVSSFLE 1192
++ +TV VY +D+ LY +L+ + E
Sbjct 134 AQIAFETVSDYLTRRPQPKQVYFVCYDEENFLLYQRLLGQYDE 176
>sp|B5F961|YMDB_SALA4 O-acetyl-ADP-ribose deacetylase OS=Salmonella
agona (strain SL483) OX=454166 GN=ymdB PE=3 SV=1
Length=179
Score = 54.3 bits (129), Expect = 5e-06, Method: Composition-based stats.
Identities = 48/176 (27%), Positives = 76/176 (43%), Gaps = 25/176 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T + + DI + + +VNAAN L GGGV GA+++A A+
Sbjct 1 MTSRLQVIQGDITQ----LSVDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G + G + + L AK +H VGP GE + +LL++AY N N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEYQEAELLEAAYRNCLLLAEANHFRSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVS 1188
P +S G++G + V V TV VY +D+ LY +L++
Sbjct 117 AFPAISTGVYGYPRAQAAEVAVRTVSDFITRYALPEQVYFVCYDEETARLYARLLT 172
>sp|A4W960|YMDB_ENT38 O-acetyl-ADP-ribose deacetylase OS=Enterobacter
sp. (strain 638) OX=399742 GN=ymdB PE=3 SV=1
Length=180
Score = 53.9 bits (128), Expect = 6e-06, Method: Composition-based stats.
Identities = 46/164 (28%), Positives = 74/164 (45%), Gaps = 21/164 (13%)
Query 1045 IVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCV 1104
+V + ++ V+VNAAN L GGGV GA+++A + G G + +
Sbjct 8 VVGDITTMEVDVIVNAANPSLMGGGGVDGAIHRAAGPQLLEACKTVRQQQGECAPGHAVI 67
Query 1105 -LSGHNLAKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVLLAPLLSAGIFG 1155
++G AK +H VGP GE + + L+ AY N N ++ L P +S G++G
Sbjct 68 TIAGDLPAKAVIHAVGPVWQGGENHEARTLQDAYLNCLRLAAANGYKTLAFPAISTGVYG 127
Query 1156 ADPIHSLRVCVDTVR---------TNVYLAVFDK---NLYDKLV 1187
+ + VDTV VY +D+ LY +L+
Sbjct 128 YPKAAAAEIAVDTVSEFLTRKPLPERVYFVCYDEENAQLYQRLL 171
>sp|P67341|YMDB_SALTY O-acetyl-ADP-ribose deacetylase OS=Salmonella
typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287
GN=ymdB PE=3 SV=1
Length=179
Score = 53.5 bits (127), Expect = 7e-06, Method: Composition-based stats.
Identities = 48/176 (27%), Positives = 75/176 (43%), Gaps = 25/176 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T + + DI + + +VNAAN L GGGV GA+++A A+
Sbjct 1 MTSRLQVIQGDITQ----LSVDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G + G + + L AK +H VGP GE + +LL+ AY N N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRNCLLLAEANHFRSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVS 1188
P +S G++G + V V TV VY +D+ LY +L++
Sbjct 117 AFPAISTGVYGYPRAQAAEVAVRTVSDFITRYALPEQVYFVCYDEETARLYARLLT 172
>sp|P67342|YMDB_SALTI O-acetyl-ADP-ribose deacetylase OS=Salmonella
typhi OX=90370 GN=ymdB PE=3 SV=1
Length=179
Score = 53.5 bits (127), Expect = 7e-06, Method: Composition-based stats.
Identities = 48/176 (27%), Positives = 75/176 (43%), Gaps = 25/176 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T + + DI + + +VNAAN L GGGV GA+++A A+
Sbjct 1 MTSRLQVIQGDITQ----LSVDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G + G + + L AK +H VGP GE + +LL+ AY N N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRNCLLLAEANHFRSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVS 1188
P +S G++G + V V TV VY +D+ LY +L++
Sbjct 117 AFPAISTGVYGYPRAQAAEVAVRTVSDFITRYALPEQVYFVCYDEETARLYARLLT 172
>sp|P0A8D6|YMDB_ECOLI O-acetyl-ADP-ribose deacetylase OS=Escherichia
coli (strain K12) OX=83333 GN=ymdB PE=1 SV=1
Length=177
Score = 53.1 bits (126), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 25/176 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++ DI K+ V+VNAAN L GGGV GA+++A A+
Sbjct 1 MKTRIHVVQGDIT----KLAVDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQ 56
Query 1094 NGPLKVGGSCV-LSGHNLAKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + L+G AK +H VGP GE + QLL+ AY N N + +
Sbjct 57 QGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSV 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDK---NLYDKLVS 1188
P +S G++G + + V TV VY +D+ +LY++L++
Sbjct 117 AFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLT 172
>sp|P0A8D7|YMDB_ECOL6 O-acetyl-ADP-ribose deacetylase OS=Escherichia
coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) OX=199310
GN=ymdB PE=3 SV=1
Length=177
Score = 53.1 bits (126), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 25/176 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++ DI K+ V+VNAAN L GGGV GA+++A A+
Sbjct 1 MKTRIHVVQGDIT----KLAVDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQ 56
Query 1094 NGPLKVGGSCV-LSGHNLAKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + L+G AK +H VGP GE + QLL+ AY N N + +
Sbjct 57 QGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSV 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDK---NLYDKLVS 1188
P +S G++G + + V TV VY +D+ +LY++L++
Sbjct 117 AFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLT 172
>sp|P0A8D8|YMDB_ECO57 O-acetyl-ADP-ribose deacetylase OS=Escherichia
coli O157:H7 OX=83334 GN=ymdB PE=3 SV=1
Length=177
Score = 53.1 bits (126), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 25/176 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++ DI K+ V+VNAAN L GGGV GA+++A A+
Sbjct 1 MKTRIHVVQGDIT----KLAVDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQ 56
Query 1094 NGPLKVGGSCV-LSGHNLAKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + L+G AK +H VGP GE + QLL+ AY N N + +
Sbjct 57 QGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSV 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDK---NLYDKLVS 1188
P +S G++G + + V TV VY +D+ +LY++L++
Sbjct 117 AFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLT 172
>sp|D3RKJ0|YMDB_KLEVT O-acetyl-ADP-ribose deacetylase OS=Klebsiella
variicola (strain At-22) OX=640131 GN=ymdB PE=3 SV=1
Length=175
Score = 53.1 bits (126), Expect = 9e-06, Method: Composition-based stats.
Identities = 45/156 (29%), Positives = 73/156 (47%), Gaps = 21/156 (13%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCV-LSGHNLAKHC 1114
V+VNAAN L GGGV GA+++A A+ + G G + + ++G A
Sbjct 19 VIVNAANPSLLGGGGVDGAIHRAAGPALLAACKQVLQQQGECPPGHAVITIAGDLPASAV 78
Query 1115 LHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVLLAPLLSAGIFGADPIHSLRVCV 1166
+H VGP + G+ + Q L AY+N N + + P +S G++G + + V
Sbjct 79 IHTVGPVWHGGDRMEAQTLADAYKNSLQLAAANNYRSIAFPAISTGVYGYPKEEAAEIAV 138
Query 1167 DTV-----RTN----VYLAVFDKN---LYDKLVSSF 1190
TV R N V FD+ +Y +L++S+
Sbjct 139 RTVTAFLTRYNPLERVLFVCFDEETAAIYRRLLASY 174
>sp|B5XXK9|YMDB_KLEP3 O-acetyl-ADP-ribose deacetylase OS=Klebsiella
pneumoniae (strain 342) OX=507522 GN=ymdB PE=3 SV=1
Length=175
Score = 53.1 bits (126), Expect = 9e-06, Method: Composition-based stats.
Identities = 45/156 (29%), Positives = 73/156 (47%), Gaps = 21/156 (13%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCV-LSGHNLAKHC 1114
V+VNAAN L GGGV GA+++A A+ + G G + + ++G A
Sbjct 19 VIVNAANPSLLGGGGVDGAIHRAAGPALLAACKQVLQQQGECPPGHAVITIAGDLPASAV 78
Query 1115 LHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVLLAPLLSAGIFGADPIHSLRVCV 1166
+H VGP + G+ + Q L AY+N N + + P +S G++G + + V
Sbjct 79 IHTVGPVWHGGDRMEAQTLADAYKNSLQLAAANNYRSIAFPAISTGVYGYPKEEAAEIAV 138
Query 1167 DTV-----RTN----VYLAVFDKN---LYDKLVSSF 1190
TV R N V FD+ +Y +L++S+
Sbjct 139 RTVTAFLTRYNPLERVLFVCFDEETAAIYRRLLASY 174
>sp|B4T2X8|YMDB_SALNS O-acetyl-ADP-ribose deacetylase OS=Salmonella
newport (strain SL254) OX=423368 GN=ymdB PE=3 SV=1
Length=179
Score = 53.1 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 47/176 (27%), Positives = 75/176 (43%), Gaps = 25/176 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T + + DI + + +VNAAN L GGGV GA+++A A+
Sbjct 1 MTSRLQVIQGDITQ----LSVDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G + G + + L AK +H VGP GE + +LL+ AY N N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRNCLLLAEANHFRSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVS 1188
P +S G++G + + V TV VY +D+ LY +L++
Sbjct 117 AFPAISTGVYGYPRAQAAEIAVRTVSDFITRYALPEQVYFVCYDEETARLYARLLT 172
>sp|Q9WJC7|POLN_EEVVM Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain Mena II) OX=36384 PE=3 SV=3
Length=2499
Score = 56.6 bits (135), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 43/141 (30%), Positives = 68/141 (48%), Gaps = 26/141 (18%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCL 1115
V+VNAAN + G GV GAL + + ++ P++VG + ++ G +KH +
Sbjct 1347 VIVNAANSKGQPGSGVCGALYRKYPESFDLQ---------PIEVGKARLVKGS--SKHII 1395
Query 1116 HVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVLLAPLLSAGIFGAD------PIH 1160
H VGPN +K +++ L AYE N N + + PLLS GIF + ++
Sbjct 1396 HAVGPNFSKVSEVEGDKQLAEAYESIAKIINDNNYRSVAIPLLSTGIFAGNKDRLMQSLN 1455
Query 1161 SLRVCVDTVRTNVYLAVFDKN 1181
L +DT +V + DK
Sbjct 1456 HLLTALDTTDADVAIYCRDKK 1476
>sp|Q460N5|PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14
OS=Homo sapiens OX=9606 GN=PARP14 PE=1 SV=3
Length=1801
Score = 56.2 bits (134), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 40/124 (32%), Positives = 61/124 (49%), Gaps = 14/124 (11%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA-KHC 1114
VVVNA+N LKH GG+A AL+KA +Q + D + G L G + + L H
Sbjct 818 VVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHV 877
Query 1115 LHVVGPNVNKGED---IQLLKSAYE------NFNQHEVLLAPLLSAGIFGADPIHSLRVC 1165
+H VGP + E + LL+ A + ++ + P +S+G+FG L C
Sbjct 878 IHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISSGVFG----FPLGRC 933
Query 1166 VDTV 1169
V+T+
Sbjct 934 VETI 937
>sp|D5CE05|YMDB_ENTCC O-acetyl-ADP-ribose deacetylase OS=Enterobacter
cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054
/ NBRC 13535 / NCTC 10005 / WDCM 00083 / NCDC 279-56) OX=716541
GN=ymdB PE=3 SV=1
Length=180
Score = 52.0 bits (123), Expect = 3e-05, Method: Composition-based stats.
Identities = 38/123 (31%), Positives = 60/123 (49%), Gaps = 9/123 (7%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCV-LSGHNLAKHC 1114
V+VNAAN L GGGV GA+++A + G G + + L+G AK
Sbjct 19 VIVNAANPSLMGGGGVDGAIHRAAGPQLLEACKTVRQQQGECPPGHAVITLAGDLPAKAV 78
Query 1115 LHVVGPNVNKGE--DIQLLKSAYENF------NQHEVLLAPLLSAGIFGADPIHSLRVCV 1166
+H VGP + G+ + +L+ AY N N ++ + P +S G++G + + V
Sbjct 79 IHAVGPIWHGGDRHEASILEEAYRNCLRLAADNGYKTMAFPAISTGVYGYPKAAAATIAV 138
Query 1167 DTV 1169
DTV
Sbjct 139 DTV 141
>sp|Q72M93|Y3295_LEPIC Macro domain-containing protein LIC_13295
OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar
copenhageni (strain Fiocruz L1-130) OX=267671 GN=LIC_13295
PE=4 SV=1
Length=175
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 52/172 (30%), Positives = 82/172 (48%), Gaps = 31/172 (18%)
Query 1045 IVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCV 1104
I E+ +++ +VNAAN L GGGV GA+++A + E G KVG + +
Sbjct 8 IKEDITQLEVDAIVNAANSSLLGGGGVDGAIHRAGGPEILEECYKIREKQGECKVGEAVI 67
Query 1105 LSGHNL-AKHCLHVVGP---NVNKGEDIQLLKSAYENFNQHEVLLA----------PLLS 1150
+ L AK +H VGP NK ED +LL +AY+N +LLA P +S
Sbjct 68 TTAGRLNAKFIIHTVGPIWSGGNKNED-ELLSNAYKN----SLLLAKNHSLKTIAFPNIS 122
Query 1151 AGIFGADPIHSLRVCVDTVRT---------NVYLAVFD-KNL--YDKLVSSF 1190
GI+ + ++ + +V V+ FD +NL Y+KL+ ++
Sbjct 123 TGIYHFPKERAAKIAIQSVTKFLKQDNQIQTVFFVCFDFENLEIYNKLLQTY 174
>sp|Q8EYT0|Y4133_LEPIN Macro domain-containing protein LA_4133
OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar
Lai (strain 56601) OX=189518 GN=LA_4133 PE=4 SV=1
Length=175
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 52/172 (30%), Positives = 82/172 (48%), Gaps = 31/172 (18%)
Query 1045 IVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCV 1104
I E+ +++ +VNAAN L GGGV GA+++A + E G KVG + +
Sbjct 8 IKEDITQLEVDAIVNAANSSLLGGGGVDGAIHRAGGPEILEECYKIREKQGECKVGEAVI 67
Query 1105 LSGHNL-AKHCLHVVGP---NVNKGEDIQLLKSAYENFNQHEVLLA----------PLLS 1150
+ L AK +H VGP NK ED +LL +AY+N +LLA P +S
Sbjct 68 TTAGRLNAKFIIHTVGPIWSGGNKNED-ELLSNAYKN----SLLLAKNHSLKTIAFPNIS 122
Query 1151 AGIFGADPIHSLRVCVDTVR---------TNVYLAVFD-KNL--YDKLVSSF 1190
GI+ + ++ + +V V+ FD +NL Y+KL+ ++
Sbjct 123 TGIYHFPKERAAKIAIQSVTEFLKQDNQIQTVFFVCFDFENLEIYNKLLQTY 174
>sp|B5RBF3|YMDB_SALG2 O-acetyl-ADP-ribose deacetylase OS=Salmonella
gallinarum (strain 287/91 / NCTC 13346) OX=550538 GN=ymdB
PE=3 SV=1
Length=179
Score = 51.6 bits (122), Expect = 4e-05, Method: Composition-based stats.
Identities = 47/176 (27%), Positives = 75/176 (43%), Gaps = 25/176 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T + + DI + + +VNAAN L GGGV GA+++A A+
Sbjct 1 MTSRLQVIQGDITQ----LSVDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G + G + + L AK +H VGP GE + +LL+ AY + N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRSCLLLAEANHFRSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVS 1188
P +S G++G + V V TV VY +D+ LY +L++
Sbjct 117 AFPAISTGVYGYPRAQAAEVAVRTVSDFITRYALPEQVYFVCYDEETARLYARLLT 172
>sp|B7LT90|YMDB_ESCF3 O-acetyl-ADP-ribose deacetylase OS=Escherichia
fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766
/ IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128
/ CDC 0568-73) OX=585054 GN=ymdB PE=3 SV=2
Length=177
Score = 51.2 bits (121), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 47/176 (27%), Positives = 77/176 (44%), Gaps = 25/176 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++ DI + A V +VNAAN L GGGV GA+++A +
Sbjct 1 MKSRIHVLQGDITQLAVDV----IVNAANSSLMGGGGVDGAIHRAAGPELLEACQKVRRQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + NL A+ +H VGP GE + QLL AY N N ++ +
Sbjct 57 QGECPTGHAVITIAGNLPARAVIHTVGPVWRDGEHNEDQLLHDAYLNSLKLAQANGYKSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDK---NLYDKLVS 1188
P +S G++G + + V TV +Y +D+ LY++L++
Sbjct 117 AFPAISTGVYGFPRAAAAEIAVKTVSDFITRHALPEQIYFVCYDEENSRLYNRLLT 172
>sp|Q0T5Z6|YMDB_SHIF8 O-acetyl-ADP-ribose deacetylase OS=Shigella
flexneri serotype 5b (strain 8401) OX=373384 GN=ymdB PE=3
SV=1
Length=177
Score = 50.8 bits (120), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 49/176 (28%), Positives = 79/176 (45%), Gaps = 25/176 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++ DI K+ V+VNAAN L GGGV GA+++A A+
Sbjct 1 MKTRIHVVQGDIT----KLAVDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQ 56
Query 1094 NGPLKVGGSCV-LSGHNLAKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + L+G AK +H VGP GE + QLL+ AY N N + +
Sbjct 57 QGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSV 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDK---NLYDKLVS 1188
P +S G++ + + V TV VY +D+ +LY++L++
Sbjct 117 AFPAISTGVYSYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLT 172
>sp|P0C6F4|R1A_BRV1 Replicase polyprotein 1a OS=Breda virus 1
OX=360393 GN=1a PE=3 SV=1
Length=4445
Score = 53.5 bits (127), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 35/105 (33%), Positives = 50/105 (48%), Gaps = 6/105 (6%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAK--HC 1114
VVN AN LKHGGG+A ++ + S++YI L V + G L K
Sbjct 1669 VVNPANNQLKHGGGIAKVISCMCGPKLTSWSNNYIKQYKKLGVTCAIRSPGFQLGKGVQI 1728
Query 1115 LHVVGPNVNKGEDIQLL----KSAYENFNQHEVLLAPLLSAGIFG 1155
+HVVGP + + L +S ++N +L +LS GIFG
Sbjct 1729 IHVVGPKSADSDVVNKLEASWRSVFQNVKPDTTVLTSMLSTGIFG 1773
Score = 44.3 bits (103), Expect = 0.062, Method: Compositional matrix adjust.
Identities = 40/154 (26%), Positives = 76/154 (49%), Gaps = 15/154 (10%)
Query 3047 IVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFL---MSFTVLCLTPVYSFLPG 3103
+V I IV L ++ F +++VV LLF+ M V+CL P+ +PG
Sbjct 2944 VVLVAIFTIVFLFLLRMYIVMYSYFKVFTYVVF--KLLFVNTVMVLFVVCLPPL---VPG 2998
Query 3104 VYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKR 3163
V V L +L + V FL ++ + +F ++P++ + +++ + F+W +
Sbjct 2999 VVFV----LALWLCDSVVFLLYLAVLSLF--ILPWFYVMLFVLIVGGFVFWWMMKSSDVV 3052
Query 3164 RVVFNGVSFS-TFEEAALCTFLLNKEMYLKLRSD 3196
+ +G++F+ TFE+ + C F LN + +L D
Sbjct 3053 HLTPDGLTFNGTFEQVSKCVFPLNPLIVNRLLLD 3086
>sp|D2TT52|YMDB_CITRI O-acetyl-ADP-ribose deacetylase OS=Citrobacter
rodentium (strain ICC168) OX=637910 GN=ymdB PE=3 SV=2
Length=177
Score = 50.1 bits (118), Expect = 1e-04, Method: Composition-based stats.
Identities = 45/176 (26%), Positives = 76/176 (43%), Gaps = 25/176 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++ + DI V +VNAAN L GGGV GA+++A +
Sbjct 1 MNSRIHVIHGDIT----TVAVDAIVNAANPSLMGGGGVDGAIHRAAGPELLEACMTVRRQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + + L AK +H VGP GE + QLL AY N N ++ +
Sbjct 57 QGECPPGHAVITAAGRLPAKAVIHTVGPIWRGGEHNEAQLLHDAYLNSLNLALANGYQSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVS 1188
P +S G++G + + V+T+ +Y +D+ LY +L++
Sbjct 117 AFPAISTGVYGYPRAAAAEIAVNTISEFITRRASPEQIYFVCYDEETTRLYQRLLT 172
>sp|Q32E73|YMDB_SHIDS O-acetyl-ADP-ribose deacetylase OS=Shigella
dysenteriae serotype 1 (strain Sd197) OX=300267 GN=ymdB
PE=3 SV=1
Length=177
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 48/172 (28%), Positives = 77/172 (45%), Gaps = 25/172 (15%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
+++ DI K+ V+VN N L GGGV GA+++A A+ G
Sbjct 5 IHVVQGDIT----KLAVDVIVNVTNPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDC 60
Query 1098 KVGGSCV-LSGHNLAKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVLLAPL 1148
G + + L+G AK +H VGP GE + QLL+ AY N N + + P
Sbjct 61 PTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPA 120
Query 1149 LSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDK---NLYDKLVS 1188
+S G++G + + V TV VY +D+ +LY++L++
Sbjct 121 ISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLT 172
>sp|Q8RHQ2|Y1951_FUSNN Uncharacterized protein FN1951 OS=Fusobacterium
nucleatum subsp. nucleatum (strain ATCC 25586 / DSM
15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG
13131 / VPI 4355) OX=190304 GN=FN1951 PE=4 SV=1
Length=175
Score = 49.3 bits (116), Expect = 2e-04, Method: Composition-based stats.
Identities = 31/82 (38%), Positives = 45/82 (55%), Gaps = 7/82 (9%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA-KHCL 1115
+VNAAN L+ GGGV GA+ KA + + E + G G + + G+NL K+ +
Sbjct 22 IVNAANSSLEMGGGVCGAIFKAAGSELAQECKEI----GGCNTGEAVITKGYNLPNKYII 77
Query 1116 HVVGPNVNKGE--DIQLLKSAY 1135
H VGP + GE + + L SAY
Sbjct 78 HTVGPRYSTGENREAERLASAY 99
>sp|Q2EMV9|PAR14_MOUSE Protein mono-ADP-ribosyltransferase PARP14
OS=Mus musculus OX=10090 GN=Parp14 PE=1 SV=3
Length=1817
Score = 51.6 bits (122), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 16/125 (13%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA-KHC 1114
VVVNAAN LKH G+A AL+KA +Q E D + G + G + + L H
Sbjct 829 VVVNAANENLKHISGLAQALSKAAGPELQTECDQIVKEGGVVLPGNAVISKAGKLPCHHV 888
Query 1115 LHVVGPNVNKGEDI--------QLLKSAYENFNQHEV--LLAPLLSAGIFGADPIHSLRV 1164
+H VGP KG+ + ++++ + +H + P +SAGIF L +
Sbjct 889 IHAVGPRW-KGDKVLECVSLLKKVVRQSLSLAEEHRCRSIAMPAVSAGIFD----FPLEL 943
Query 1165 CVDTV 1169
CV +
Sbjct 944 CVANI 948
>sp|Q8Q0F9|Y177_METMA Macro domain-containing protein MM_0177
OS=Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1
/ Go1 / JCM 11833 / OCM 88) OX=192952 GN=MM_0177 PE=4 SV=1
Length=187
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 51/165 (31%), Positives = 76/165 (46%), Gaps = 28/165 (17%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNG 1095
D + I DIV K++ +VNAAN L GGGV GA+++A A+ E NG
Sbjct 19 DRIRIFEGDIV----KMRVDAIVNAANNTLLGGGGVDGAIHRAAGPALLEECK---TLNG 71
Query 1096 PLKVGGSCVLSGHNL-AKHCLHVVGP---NVNKGEDIQLLKSAYENFNQH------EVLL 1145
G + + SG+ L AK+ +H VGP KGED +LL S Y + + +
Sbjct 72 -CPTGEAKITSGYLLPAKYIIHTVGPVWQGGEKGED-ELLASCYRKSLELARDYKIKTIA 129
Query 1146 APLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN 1181
P +S G +G + + V V+ VYL ++K+
Sbjct 130 FPAISTGAYGFPSERAAGIAVSQVKEFLQKNEIPETVYLVCYNKD 174
>sp|Q87JZ5|Y4103_VIBPA Macro domain-containing protein VPA0103
OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
OX=223926 GN=VPA0103 PE=4 SV=1
Length=170
Score = 47.8 bits (112), Expect = 7e-04, Method: Composition-based stats.
Identities = 41/138 (30%), Positives = 65/138 (47%), Gaps = 14/138 (10%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQ---VESDDYIATNGPLKVGGSCVLSGHNL-AK 1112
+VNAAN + GGGV GA+++A A+ DD P G + + NL A+
Sbjct 19 IVNAANPRMLGGGGVDGAIHRAAGPALINACYAVDDVDGIRCPF--GDARITEAGNLNAR 76
Query 1113 HCLHVVGPNVNKGEDIQ-LLKSAYEN------FNQHEVLLAPLLSAGIFGADPIHSLRVC 1165
+ +H VGP +K D + +L+SAY+ N + + P +S G++G P + V
Sbjct 77 YVIHAVGPIYDKFADPKTVLESAYQRSLDLALANHCQSVALPAISCGVYGYPPQEAAEVA 136
Query 1166 VDTVRTNVYLAVFDKNLY 1183
+ + Y A D Y
Sbjct 137 MAVCQRPEY-AALDMRFY 153
>sp|Q8IXQ6|PARP9_HUMAN Protein mono-ADP-ribosyltransferase PARP9
OS=Homo sapiens OX=9606 GN=PARP9 PE=1 SV=2
Length=854
Score = 50.4 bits (119), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 44/142 (31%), Positives = 65/142 (46%), Gaps = 16/142 (11%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA-KHCL 1115
VVNAAN L HGGG+A AL KA +Q ES ++A G + G V L K +
Sbjct 135 VVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQII 194
Query 1116 HVVGPNVNKGE------DIQLLKSAYENF----NQH-EVLLAPLLSAGIFGADPIHSLRV 1164
H VGP + + +Q + N+ N H + + P LS+GIF L +
Sbjct 195 HAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQ----FPLNL 250
Query 1165 CVDTVRTNVYLAVFDKNLYDKL 1186
C T+ + +++ K + L
Sbjct 251 CTKTIVETIRVSLQGKPMMSNL 272
>sp|Q8RB30|Y995_CALS4 Macro domain-containing protein TTE0995
OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain
DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=TTE0995
PE=4 SV=1
Length=175
Score = 47.4 bits (111), Expect = 8e-04, Method: Composition-based stats.
Identities = 47/154 (31%), Positives = 67/154 (44%), Gaps = 31/154 (20%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCL 1115
+VNAAN L GGGV GA++KA A+ E G G + + NL AK+ +
Sbjct 20 IVNAANSSLIGGGGVDGAIHKAGGPAIAEELKVIREKQGGCPTGHAVITGAGNLKAKYVI 79
Query 1116 HVVGP---NVNKGEDIQLLKSAY-------ENFNQHEVLLAPLLSAGIFGADPIHSLRVC 1165
H VGP N ED LL SAY + +N + P +S G +G + R+
Sbjct 80 HAVGPIWKGGNHNED-NLLASAYIESLKLADEYNVKTIAF-PSISTGAYGFPVERAARIA 137
Query 1166 VDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQV 1199
+ ++VS +LE S K+V
Sbjct 138 L------------------RVVSDYLEGSSIKEV 153
>sp|E1PL40|YMDB2_PANVC O-acetyl-ADP-ribose deacetylase 2 OS=Pantoea
vagans (strain C9-1) OX=712898 GN=ymdB2 PE=3 SV=1
Length=171
Score = 47.4 bits (111), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 44/151 (29%), Positives = 66/151 (44%), Gaps = 18/151 (12%)
Query 1052 VKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL- 1110
+ ++N AN L GGGV GA+++A + E + G KVG + + L
Sbjct 14 IASEAIINVANSSLLGGGGVDGAIHRAGGPVILAECQAIRSRQGGCKVGEAVITGAGTLP 73
Query 1111 AKHCLHVVGPNVNKG---EDIQLLK---SAYENFNQHEVLLA--PLLSAGIFG------- 1155
A + +H VGP + G ED QL S ++ H + P +S GI+G
Sbjct 74 ADYVIHTVGPRWSDGRHNEDTQLKSVYLSCFKLVGHHGIKTVSFPNISTGIYGFPKKRAA 133
Query 1156 ADPIHSLRVCVDTVRT--NVYLAVFDKNLYD 1184
A + ++ C+ RT V L FD YD
Sbjct 134 AIALDVIKHCIAENRTIEKVNLVCFDAENYD 164
>sp|Q8TQD0|Y1614_METAC Macro domain-containing protein MA_1614
OS=Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834
/ JCM 12185 / C2A) OX=188937 GN=MA_1614 PE=4 SV=1
Length=195
Score = 47.8 bits (112), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 51/166 (31%), Positives = 78/166 (47%), Gaps = 22/166 (13%)
Query 1018 PVVQTIEVNSFSGYLKLTDN---VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGA 1074
P + ++ NS L ++ N + I DI E +K +VNAAN L GGGV GA
Sbjct 6 PYKKELKRNSRKRSLNMSQNSERIRIIERDITE----LKVDAIVNAANNTLLGGGGVDGA 61
Query 1075 LNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGP---NVNKGEDIQL 1130
+++A + E NG G + + G+ L AK+ +H VGP KGED +
Sbjct 62 IHRAAGPGLLEECR---TLNG-CPTGEAKITKGYLLPAKYVIHTVGPIWQEGTKGED-EF 116
Query 1131 LKSAY----ENFNQHEV--LLAPLLSAGIFGADPIHSLRVCVDTVR 1170
L S Y E +++V + P +S G +G + R+ V V+
Sbjct 117 LASCYRKSLELARKYDVKTIAFPTISTGAYGFPSERAARIAVSQVK 162
>sp|Q92355|SEN1_SCHPO Helicase sen1 OS=Schizosaccharomyces pombe
(strain 972 / ATCC 24843) OX=284812 GN=sen1 PE=1 SV=1
Length=1687
Score = 49.7 bits (117), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 67/244 (27%), Positives = 103/244 (42%), Gaps = 43/244 (18%)
Query 5695 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV-CRLM 5753
V+ DE + A D +++ R AK + +GDP QLP T+L+K Y S+ R+
Sbjct 1375 VIIDEAAQAVELD-TIIPLRYGAKKCILVGDPNQLPP--TVLSKKAASLNYSQSLFVRIQ 1431
Query 5754 KTIGPDM-FLGTCRRCPAEIVDTVSALVYDNKLKA------------HKDKSAQCFKMF- 5799
K M L R +I S YD++L+ H + +++F
Sbjct 1432 KNFSNQMCLLSIQYRMHPDISHFPSKKFYDSRLEDGDNMAEKTQQVWHVNPKFTQYRLFD 1491
Query 5800 YKGV-ITHDVSSAINRPQ----IGVVREFLTRNP----AWRKAVFISPYNSQ-----NAV 5845
+G T + S N + + +V E L + P R V I+PY SQ A
Sbjct 1492 VRGKERTSNTMSTYNLEEVEYLVNMVDELLNKFPDVNFTGRIGV-ITPYRSQLHELRRAF 1550
Query 5846 ASK-----ILGLPTQTVDSSQGSEYDYVIFT-QTTETAHSC----NVNRFNVAITRAKVG 5895
K + + QTVD QG E D + F+ + + H + R NVA+TRA+
Sbjct 1551 KVKYGKSFMSTIDIQTVDGFQGQEKDIIFFSCVKSYSKHGIGFLRDFRRLNVALTRARSS 1610
Query 5896 ILCI 5899
+L I
Sbjct 1611 LLII 1614
>sp|P38859|DNA2_YEAST DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Saccharomyces cerevisiae (strain ATCC 204508
/ S288c) OX=559292 GN=DNA2 PE=1 SV=1
Length=1522
Score = 49.3 bits (116), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 58/211 (27%), Positives = 90/211 (43%), Gaps = 28/211 (13%)
Query 5599 QKYSTLQGPPGTGKSHF--AIGLALYYPSARIVYTACSHAAVDALCEK-----------A 5645
+ Y+ + G PGTGK+ I L R++ T+ +H+AVD + K
Sbjct 1067 EDYALILGMPGTGKTTVIAEIIKILVSEGKRVLLTSYTHSAVDNILIKLRNTNISIMRLG 1126
Query 5646 LKYLPIDKCSRIIPARARVECFDKF--KVNSTLEQYVFCT-VN----ALPETTADIVVFD 5698
+K+ + +P A V+ ++ + K+NST C +N L E D V+ D
Sbjct 1127 MKHKVHPDTQKYVPNYASVKSYNDYLSKINSTSVVATTCLGINDILFTLNEKDFDYVILD 1186
Query 5699 EISMATNYDLSVVNARLR-AKHYVYIGDPAQLP--APRTLLTKGTLEPEYFNSVCRLMKT 5755
E A+ + V LR ++ +GD QLP G LE F + C
Sbjct 1187 E---ASQISMPVALGPLRYGNRFIMVGDHYQLPPLVKNDAARLGGLEESLFKTFCEKHPE 1243
Query 5756 IGPDMFLGTCRRCPAEIVDTVSALVYDNKLK 5786
++ L R C +IV + L+YDNKLK
Sbjct 1244 SVAELTL-QYRMC-GDIVTLSNFLIYDNKLK 1272
>sp|Q8Y2K1|Y334_RALN1 Macro domain-containing protein RSc0334
OS=Ralstonia nicotianae (strain GMI1000) OX=267608 GN=RSc0334
PE=4 SV=1
Length=171
Score = 46.2 bits (108), Expect = 0.002, Method: Composition-based stats.
Identities = 40/123 (33%), Positives = 63/123 (51%), Gaps = 13/123 (11%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCL 1115
+VNAAN L GGGV GA+++A + + A +G + G + + G L A++ +
Sbjct 23 IVNAANSALLGGGGVDGAIHRAAGPELL---EACRALHG-CRTGQAKITPGFLLPARYII 78
Query 1116 HVVGPNVNKG--EDIQLLKSAYEN----FNQHEV--LLAPLLSAGIFGADPIHSLRVCVD 1167
H VGP G ++ LL + Y N QH+V + P +S G++G P + + V
Sbjct 79 HTVGPIWRGGRQDEAALLAACYRNSLALAKQHDVRTIAFPCISTGVYGFPPQLAAPIAVR 138
Query 1168 TVR 1170
TVR
Sbjct 139 TVR 141
>sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 OS=Arabidopsis
thaliana OX=3702 GN=SDE3 PE=1 SV=1
Length=1002
Score = 48.5 bits (114), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 98/388 (25%), Positives = 144/388 (37%), Gaps = 100/388 (26%)
Query 5604 LQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAAVDALCEKAL----------KYL 5649
+ GPPGTGK+ + L +AR++ A S++A D + EK L +
Sbjct 419 IHGPPGTGKTMTLVEAIVQLYTTQRNARVLVCAPSNSAADHILEKLLCLEGVRIKDNEIF 478
Query 5650 PIDKCSR----IIPARARVECFDK--FK------------VNSTLEQYVFCTVNALPETT 5691
++ +R I P R FD+ FK V ST +
Sbjct 479 RLNAATRSYEEIKPEIIRFCFFDELIFKCPPLKALTRYKLVVSTYMSASLLNAEGVNRGH 538
Query 5692 ADIVVFDEISMATNYD--LSVVNARLRAKHYVYIGDPAQL-------PAPRTLLTKGTLE 5742
++ DE A+ + ++V N L V GDP QL A L K LE
Sbjct 539 FTHILLDEAGQASEPENMIAVSNLCLTETVVVLAGDPRQLGPVIYSRDAESLGLGKSYLE 598
Query 5743 P----EYF-----NSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSA 5793
+Y+ N V +L+K RC EI+D S L YD +L A K+ +
Sbjct 599 RLFECDYYCEGDENYVTKLVKNY----------RCHPEILDLPSKLFYDGELVASKEDTD 648
Query 5794 QC-----------FKMFYKGVITHDVS-----SAINRPQIGVVREFLTRNPA-----WRK 5832
F M + G+ D S NR +I V E + R A
Sbjct 649 SVLASLNFLPNKEFPMVFYGIQGCDEREGNNPSWFNRIEISKVIETIKRLTANDCVQEED 708
Query 5833 AVFISPYNSQNAVASKILG------LPTQTVDSSQGSEYDYVIFTQTTET-AHS------ 5879
I+PY Q ++L + +V+ QG E +I + T H+
Sbjct 709 IGVITPYRQQVMKIKEVLDRLDMTEVKVGSVEQFQGQEKQVIIISTVRSTIKHNEFDRAY 768
Query 5880 -----CNVNRFNVAITRAKVGILCIMSD 5902
N RFNVAITRA + +L I+ +
Sbjct 769 CLGFLSNPRRFNVAITRA-ISLLVIIGN 795
>sp|Q68772|RPOA_SHFV Replicase polyprotein 1ab OS=Simian hemorrhagic
fever virus OX=38143 GN=rep PE=2 SV=4
Length=3595
Score = 48.1 bits (113), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 68/286 (24%), Positives = 119/286 (42%), Gaps = 33/286 (12%)
Query 4833 FFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVI-----V 4887
++ Q G A + D ++NL T I L V+ +V Y G I I V
Sbjct 2333 YYTQHGCEAAALQDLKKFNLSTQGFI--LPEVLNIVRNYLL----GTIGYRPAIYKPSTV 2386
Query 4888 NNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRAR 4947
+ D AG + L + D D L V T+T + LK +K + R
Sbjct 2387 PSNDSHAGINGLSFSTKTL----QALPDIDELCEKAIAEVWQTVTPVTLKKQFCSKAKTR 2442
Query 4948 TVAGVSICSTMTNRQFHQKLLKSIA-ATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHL 5006
T+ G + +++ R + + A + + + +G SKF +V+
Sbjct 2443 TILGTNAMASLALRALLSGVTQGFQLAGKNSPICLGKSKF--------DPCTFEVKG-RC 2493
Query 5007 MGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLY 5066
+ D CDR+ P ++R A+ +L C + Y + N C ++++ S
Sbjct 2494 LETDLASCDRSTPAIVRHFATKLLFE--MACAERALPLY-VVNCC----HDLIVTQTSAA 2546
Query 5067 VKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYV 5112
K GG SSGD T+ AN+++++ V V LL +G+ ++ K++
Sbjct 2547 TKRGGLSSGDPVTSIANTIYSLVLYVQHMVLTLLE-NGHPLSLKFL 2591
>sp|Q9EYI6|Y189_STRNO Macro domain-containing protein in sno 5'region
OS=Streptomyces nogalater OX=38314 PE=4 SV=1
Length=181
Score = 45.4 bits (106), Expect = 0.005, Method: Composition-based stats.
Identities = 47/144 (33%), Positives = 67/144 (47%), Gaps = 16/144 (11%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT--NGPLKVGGSCVLSGHNL-AKH 1113
+VNAAN L GGGV GA+++ A+ E A+ L G + + +L A+
Sbjct 19 LVNAANSSLLGGGGVDGAIHRRGGPAILAECRALRASRYGEGLPTGRAVATTAGDLDARW 78
Query 1114 CLHVVGPNVNKGED-IQLLKSAY-ENFNQHEVLLA-----PLLSAGIFGADPIHSLRVCV 1166
+H VGP + ED LL S Y E+ L A P LS G++ + R+ V
Sbjct 79 VIHTVGPVWSSTEDRSDLLASCYRESLRLAGELGARTVAFPALSTGVYRWPMGDAARIAV 138
Query 1167 DTVRTN------VYLAVFDKNLYD 1184
+TVRT V +FD + YD
Sbjct 139 ETVRTTPTAVEEVRFVLFDTHAYD 162
>sp|Q9WJB2|RPOA_PRRSR Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain VR-2332) OX=300559
GN=rep PE=1 SV=2
Length=3960
Score = 47.8 bits (112), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 59/248 (24%), Positives = 105/248 (42%), Gaps = 30/248 (12%)
Query 4846 DYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKS-AGFPFNKWGKA 4904
D +Y+L T + L V+ +V KY + G C ++ S AG N++
Sbjct 2744 DLSKYDLSTQGFV--LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAGINGNRFPTK 2801
Query 4905 RLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFH 4964
D S + D L A R T+T LK K + RT+ G + + +R
Sbjct 2802 ----DIQSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNFIALAHRAVL 2857
Query 4965 QKLLKS-IAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHL---MGWDYPKCDRAMPN 5020
+ + + + + +G +KF +++ P L + D CDR+ P
Sbjct 2858 SGVTQGFMKKAFNSPIALGKNKF------------KELQTPVLGRCLEADLASCDRSTPA 2905
Query 5021 MLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTA 5080
++R A+ +L + C+ H + N C +L V G++ K GG SSGD T+
Sbjct 2906 IVRWFAANLL---YELACAEEHLPSYVLNCCHDLL---VTQSGAV-TKRGGLSSGDPITS 2958
Query 5081 YANSVFNI 5088
+N+++++
Sbjct 2959 VSNTIYSL 2966
Score = 40.8 bits (94), Expect = 0.71, Method: Compositional matrix adjust.
Identities = 39/158 (25%), Positives = 66/158 (42%), Gaps = 30/158 (19%)
Query 6629 NYY--KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEH 6686
+YY K V G Q LPET F+ R +E+D E D R + + H
Sbjct 3668 SYYLTKFVKGGAQVLPETVFSTGR----------IEVDCREYLDD----REREVAASLPH 3713
Query 6687 IVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSV 6746
GD + +GG H + R+ L +P +S + + ++K +C++
Sbjct 3714 GFIGDVKGTTVGGCH---HVTSRY------LPRVLPKESVAVVGVSSPGK--AAKALCTL 3762
Query 6747 IDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLW 6784
D+ L D + + SK K+ +D+ E+ M+W
Sbjct 3763 TDVYLPDLEAYLHPE---TQSKCWKMMLDFKEVRLMVW 3797
>sp|Q8KAE4|Y2219_CHLTE Macro domain-containing protein CT2219
OS=Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC
103806 / TLS) OX=194439 GN=CT2219 PE=4 SV=1
Length=172
Score = 44.7 bits (104), Expect = 0.007, Method: Composition-based stats.
Identities = 45/148 (30%), Positives = 66/148 (45%), Gaps = 19/148 (13%)
Query 1034 LTDNVYIK--NADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
+ DNV I ADI + +VNAAN L GGGV GA+++A + +
Sbjct 1 MPDNVLIHAIKADITS----LTVDAIVNAANTSLLGGGGVDGAIHRAAGPKLLEACREL- 55
Query 1092 ATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN-----FNQHEV 1143
G G + + G+ L A +H VGP + G + +LL S Y N H
Sbjct 56 ---GGCLTGEAKITKGYRLPATFVIHTVGPVWHGGNHGEAELLASCYRNSLKLAIEHHCR 112
Query 1144 LLA-PLLSAGIFGADPIHSLRVCVDTVR 1170
+A P +S GI+G + + + TVR
Sbjct 113 TIAFPSISTGIYGYPVEQAAAIAITTVR 140
>sp|Q97AU0|Y719_THEVO Uncharacterized protein TV0719 OS=Thermoplasma
volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 /
NBRC 15438 / GSS1) OX=273116 GN=TV0719 PE=4 SV=1
Length=186
Score = 45.1 bits (105), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 39/110 (35%), Positives = 57/110 (52%), Gaps = 12/110 (11%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGP--LKVGGSCVLSGHNL-AKH 1113
+VNAAN L GGGV GA++ + +E + T P L G + + SG L AK+
Sbjct 26 IVNAANPSLMGGGGVDGAIHLKGGKTIDLECAELRRTKWPKGLPPGEADITSGGKLKAKY 85
Query 1114 CLHVVGPNVNKG--EDIQLLKSAY----ENFNQHEV--LLAPLLSAGIFG 1155
+H VGP + +G ED + L S+Y E H + + P +S GI+G
Sbjct 86 VIHTVGP-IYRGQEEDAETLYSSYYRSLEIAKIHGIKCIAFPAISTGIYG 134
>sp|Q93SX7|Y189_ACISE Macro domain-containing protein OS=Acinetobacter
sp. (strain ED45-25) OX=194927 PE=4 SV=1
Length=183
Score = 44.7 bits (104), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 44/140 (31%), Positives = 61/140 (44%), Gaps = 21/140 (15%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
V++ ADI A +VN+AN L GGG+ ++K M+ E G
Sbjct 4 VHLIQADITAFAVHA----IVNSANKSLLGGGGLDYVIHKKAGPLMKEECVRLNQEKGGC 59
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYENFNQHEVLLAPLLSAGIF 1154
G + V + NL AK+ +H VGP GE + QLL AY N +F
Sbjct 60 PTGQAEVTTAGNLPAKYLIHAVGPRWLDGEHNEPQLLCDAYSN--------------ALF 105
Query 1155 GADPIHSLRVCVDTVRTNVY 1174
A+ IH+L V + T VY
Sbjct 106 KANEIHALTVSFPCISTGVY 125
>sp|A6YQT5|RPOA_PRRSV Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus OX=28344 PE=1 SV=2
Length=3931
Score = 47.0 bits (110), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 62/247 (25%), Positives = 104/247 (42%), Gaps = 28/247 (11%)
Query 4846 DYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKS-AGFPFNKWGKA 4904
D +Y+L T + L V+ +V KY + G C ++ S AG N++
Sbjct 2715 DLSKYDLSTQGFV--LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAGINGNRFPTK 2772
Query 4905 RLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFH 4964
D S + D L A R T+T LK K + RT+ G + + +R
Sbjct 2773 ----DIQSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNFIALAHR--- 2825
Query 4965 QKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHL---MGWDYPKCDRAMPNM 5021
AA G T K + + K + +++ P L + D CDR+ P +
Sbjct 2826 -------AALSGVTQGF-MKKAFNSPIALGKNKFKELQAPVLGRCLEADLASCDRSTPAI 2877
Query 5022 LRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAY 5081
+R A+ +L + C+ H + N C +L V G++ K GG SSGD T+
Sbjct 2878 VRWFAANLL---YELACAEEHLPSYVLNCCHDLL---VTQSGAV-TKRGGLSSGDPITSV 2930
Query 5082 ANSVFNI 5088
+N+++++
Sbjct 2931 SNTIYSL 2937
Score = 44.3 bits (103), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 48/191 (25%), Positives = 80/191 (42%), Gaps = 34/191 (18%)
Query 6600 VKGLQPSVGPKQASLNGVTLIGEAV----KTQFNYY--KKVDGVVQQLPETYFTQSRNLQ 6653
V L+P +A + ++G +V +YY K V G Q LPET F+ R
Sbjct 3606 VASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVRGEAQVLPETVFSTGR--- 3662
Query 6654 EFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKES 6713
+E+D E D ER E + H GD + +GG H + ++
Sbjct 3663 -------IEVDCREYLDDR--EREVAE--SLPHAFIGDVKGTTVGGCH---HVTSKY--- 3705
Query 6714 PFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVT 6773
L F+P +S + + ++K VC++ D+ L D + + S+ KV
Sbjct 3706 ---LPRFLPKESVAVVGVSSPGK--AAKAVCTLTDVYLPDLEAYLHPE---TQSRCWKVM 3757
Query 6774 IDYTEISFMLW 6784
+D+ E+ M+W
Sbjct 3758 LDFKEVRLMVW 3768
>sp|Q88SK6|Y3408_LACPL Macro domain-containing protein lp_3408
OS=Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB
8826 / WCFS1) OX=220668 GN=lp_3408 PE=4 SV=1
Length=172
Score = 44.3 bits (103), Expect = 0.010, Method: Composition-based stats.
Identities = 36/116 (31%), Positives = 57/116 (49%), Gaps = 19/116 (16%)
Query 1051 KVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL---KVGGSCVLSG 1107
K+ +VNAAN L GGGV GA+++A A+ +A PL G + + G
Sbjct 13 KMTVDAIVNAANTSLLGGGGVDGAIHRAAGPAL-------LAACRPLHGCATGEAKITPG 65
Query 1108 HNL-AKHCLHVVGPNVNKGE--DIQLLKSAYENF------NQHEVLLAPLLSAGIF 1154
L AK+ +H GP G+ ++QLL ++Y N N + + P +S G++
Sbjct 66 FRLPAKYVIHTPGPVWQGGQHNELQLLANSYRNSLNLAAENHCQTVAFPSISTGVY 121
>sp|Q985D2|Y7730_RHILO Macro domain-containing protein mll7730
OS=Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 /
MAFF 303099) OX=266835 GN=mll7730 PE=4 SV=1
Length=176
Score = 44.3 bits (103), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 45/132 (34%), Positives = 64/132 (48%), Gaps = 19/132 (14%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
K D + I DI K+ +VNAAN L GGGV GA+++A ++VE
Sbjct 3 KALDRIRIHTGDIT----KLDVDAIVNAANTLLLGGGGVDGAIHRAAGRELEVECR---M 55
Query 1093 TNGPLKVGGSCVLSGHNL-AKHCLHVVGP---NVNKGEDIQLLKSAYEN------FNQHE 1142
NG KVG + + G+ L A+H +H VGP KGE +LL S Y + N
Sbjct 56 LNG-CKVGDAKITKGYKLPARHIIHTVGPVWQGGGKGE-AELLASCYRSSLELAAANDCR 113
Query 1143 VLLAPLLSAGIF 1154
+ P +S G++
Sbjct 114 SVAFPAISTGVY 125
>sp|Q8B912|RPOA_PRRSB Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain HB-1) OX=300563
GN=rep PE=2 SV=3
Length=3961
Score = 47.0 bits (110), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 62/247 (25%), Positives = 104/247 (42%), Gaps = 28/247 (11%)
Query 4846 DYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKS-AGFPFNKWGKA 4904
D +Y+L T + L V+ +V KY + G C ++ S AG N++
Sbjct 2745 DLSKYDLVTQGFV--LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAGINGNRFPTK 2802
Query 4905 RLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFH 4964
D S + D L A R T+T LK K + RT+ G + + +R
Sbjct 2803 ----DIQSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNFIALAHR--- 2855
Query 4965 QKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHL---MGWDYPKCDRAMPNM 5021
AA G T K + + K + +++ P L + D CDR+ P +
Sbjct 2856 -------AALSGVTQGF-MKKAFNSPIALGKNKFKELQTPVLGRCLEADLASCDRSTPAI 2907
Query 5022 LRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAY 5081
+R A+ +L + C+ H + N C +L V G++ K GG SSGD T+
Sbjct 2908 VRWFAANLL---YELACAEEHLPSYVLNCCHDLL---VTQSGAV-TKRGGLSSGDPITSV 2960
Query 5082 ANSVFNI 5088
+N+++++
Sbjct 2961 SNTIYSL 2967
Score = 43.9 bits (102), Expect = 0.095, Method: Compositional matrix adjust.
Identities = 42/158 (27%), Positives = 67/158 (42%), Gaps = 30/158 (19%)
Query 6629 NYY--KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEH 6686
+YY K V G Q LPET F+ R +E+D E D ER E + H
Sbjct 3669 SYYLTKFVRGEAQVLPETVFSTGR----------IEVDCREYLDDR--EREVAE--SLPH 3714
Query 6687 IVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSV 6746
GD + +GG H + ++ L F+P +S + + ++K C++
Sbjct 3715 AFIGDVKGTTVGGCH---HVTSKY------LPRFLPKESVAVVGVSSPGE--AAKAFCTL 3763
Query 6747 IDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLW 6784
D+ L D + + SK KV +D+ E+ M+W
Sbjct 3764 TDVYLPDLEAYLHPE---TQSKCWKVMLDFKEVRLMVW 3798
>sp|P30771|RENT1_YEAST ATP-dependent helicase NAM7 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=NAM7
PE=1 SV=1
Length=971
Score = 46.6 bits (109), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 49/208 (24%), Positives = 81/208 (39%), Gaps = 22/208 (11%)
Query 5803 VITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQ--TVDSS 5860
+IT + QIGV+ P + +I Y N K L + + +VD+
Sbjct 712 IITKLFRDGVKPEQIGVI------TPYEGQRAYILQYMQMNGSLDKDLYIKVEVASVDAF 765
Query 5861 QGSEYDYVIFTQTTETAHSC-----NVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLE 5915
QG E DY+I + + R NV +TRAK G++ + + R L + L
Sbjct 766 QGREKDYIILSCVRANEQQAIGFLRDPRRLNVGLTRAKYGLVILGNPRSLARNTLWNHLL 825
Query 5916 IPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMT 5975
I R L E + C+ + + P T ++ +F E D P +D
Sbjct 826 IHFREKGCL-VEGTLDNLQLCT--VQLVRPQPRKTERPMNAQFNVESEMGDFPKF-QDFD 881
Query 5976 YRRLISMMGFKMNYQVNGYPNMFITREE 6003
+ ++S G Q+ + N F+ E
Sbjct 882 AQSMVSFSG-----QIGDFGNAFVDNTE 904
>sp|Q9YN02|RPOA_PRRS1 Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain 16244B) OX=300561
GN=rep PE=1 SV=3
Length=3961
Score = 46.6 bits (109), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 60/245 (24%), Positives = 104/245 (42%), Gaps = 24/245 (10%)
Query 4846 DYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKS-AGFPFNKWGKA 4904
D +Y+L T + L V+ +V KY + G C ++ S AG N++
Sbjct 2745 DLSKYDLSTQGFV--LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAGINGNRFPTK 2802
Query 4905 RLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFH 4964
D S + D L A R T+T LK K + RT+ G + + +R
Sbjct 2803 ----DIQSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNFIALAHRAAL 2858
Query 4965 QKLLKS-IAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLR 5023
+ + + + + +G +KF K + + V L D CDR+ P ++R
Sbjct 2859 SGVTQGFMKKAFNSPIALGKNKF--------KELQTSVLGRCLEA-DLASCDRSTPAIVR 2909
Query 5024 IMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYAN 5083
A+ +L + C+ H + N C +L V G++ K GG SSGD T+ +N
Sbjct 2910 WFAANLL---YELACAEEHLPSYVLNCCHDLL---VTQSGAV-TKRGGLSSGDPITSVSN 2962
Query 5084 SVFNI 5088
+++++
Sbjct 2963 TIYSL 2967
Score = 41.6 bits (96), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 39/158 (25%), Positives = 66/158 (42%), Gaps = 30/158 (19%)
Query 6629 NYY--KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEH 6686
+YY K V G Q LPET F+ R +E+D E D R + + H
Sbjct 3669 SYYLTKFVKGEAQLLPETVFSTGR----------IEVDCREYLDD----REREVAASLPH 3714
Query 6687 IVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSV 6746
GD + +GG H + R+ L +P +S + + ++K +C++
Sbjct 3715 AFIGDVKGTTVGGCH---HVTSRY------LPRVLPKESVAVVGVSSPGK--AAKALCTL 3763
Query 6747 IDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLW 6784
D+ L D + + SK K+ +D+ E+ M+W
Sbjct 3764 TDVYLPDLEAYLHPE---TQSKCWKMMLDFKEVRLMVW 3798
>sp|O59182|Y1513_PYRHO Uncharacterized protein PH1513 OS=Pyrococcus
horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974
/ NBRC 100139 / OT-3) OX=70601 GN=PH1513 PE=4 SV=1
Length=190
Score = 43.5 bits (101), Expect = 0.021, Method: Composition-based stats.
Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 35/165 (21%)
Query 1051 KVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQ------------------VESDDYIA 1092
K + +VNAAN YL+HGGGVA A+ KA + + +E + +
Sbjct 14 KFRAEAIVNAANKYLEHGGGVAYAIAKAASGDVSEYTRISKEEMRRQLGKDWIEHGEVVV 73
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGP------NVNKGEDIQL-LKSAYENFNQHEV-- 1143
T P+K+ N K+ +H VGP + +K E ++L + A + ++ V
Sbjct 74 TP-PMKL-------KENGVKYVIHTVGPYCGGVWSKDKEEKLKLAILGALKKADELGVKS 125
Query 1144 LLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS 1188
+ P +SAGI+G +R + V+ + +A K +Y L S
Sbjct 126 IAFPAISAGIYGCPLKEVVRTFKEVVKEFLKVANHVKEVYLVLYS 170
>sp|Q9V0Y3|Y656_PYRAB Uncharacterized protein PYRAB06560 OS=Pyrococcus
abyssi (strain GE5 / Orsay) OX=272844 GN=PYRAB06560
PE=4 SV=2
Length=183
Score = 43.1 bits (100), Expect = 0.026, Method: Composition-based stats.
Identities = 44/162 (27%), Positives = 81/162 (50%), Gaps = 28/162 (17%)
Query 1051 KVKPTVVVNAANVYLKHGGGVAGALNKA----TNNAMQVESDDYIATNGP--LKVGGSCV 1104
+ K +VNAAN YL+HGGGVA A+ KA + +++ ++ G ++ G V
Sbjct 11 RFKAEAIVNAANKYLEHGGGVAYAIAKAASGDVSEYIRISKEEMRKQIGRDWIEHGEVVV 70
Query 1105 LSGHNLA----KHCLHVVGP------NVNKGEDIQL-LKSAYENFNQHEV--LLAPLLSA 1151
NLA K+ +H VGP + +K + ++L + A + ++ V + P +SA
Sbjct 71 TPPLNLAKNGVKYVIHTVGPYCGGKWDEDKRKKLELAILGALKKADELGVRSIAFPAISA 130
Query 1152 GIFGA---DPIHSLRVCVDTVR------TNVYLAVFDKNLYD 1184
GI+G + + + ++ V+ T+VYL ++ + Y+
Sbjct 131 GIYGCPLEEVVKTFKLVVNEFLKSAKNVTDVYLVLYSERDYE 172
>sp|P19811|RPOA_EAVBU Replicase polyprotein 1ab OS=Equine arteritis
virus (strain Bucyrus) OX=299386 GN=rep PE=1 SV=3
Length=3175
Score = 45.4 bits (106), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 40/160 (25%), Positives = 70/160 (44%), Gaps = 30/160 (19%)
Query 6626 TQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFE 6685
T + + VDG + LP++ F+ R F+ S+ FL+ A ++F A
Sbjct 2917 TSYWLTEWVDGKARALPDSLFSSGR----FETNSRA---FLDEAEEKFAA-------AHP 2962
Query 6686 HIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTG-SSKCVC 6744
H G+ + S +GG H + F + L +P D+ + + G ++K C
Sbjct 2963 HACLGEINKSTVGGSHFI------FSQ---YLPPLLPADAVA---LVGASLAGKAAKAAC 3010
Query 6745 SVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLW 6784
SV+D+ F + + L S+V K+ ID+ M+W
Sbjct 3011 SVVDVYAPSFEPYLHPETL---SRVYKIMIDFKPCRLMVW 3047
>sp|P27283|POLN_SINDO Polyprotein P1234 OS=Sindbis virus subtype
Ockelbo (strain Edsbyn 82-5) OX=31699 PE=3 SV=2
Length=2515
Score = 45.4 bits (106), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 50/175 (29%), Positives = 75/175 (43%), Gaps = 39/175 (22%)
Query 1043 ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGS 1102
AD EEA VVNAAN + G GV A+ K N+ T+ + G +
Sbjct 1359 ADCQEEA-------VVNAANPLGRPGEGVCRAIYKRWPNSF---------TDSATETGTA 1402
Query 1103 CVLSGHNLAKHCLHVVGPNVNK---GEDIQLLKSAYEN----FNQHEV--LLAPLLSAGI 1153
+ H K +H VGP+ K E ++LL++AY N+H + + PLLS GI
Sbjct 1403 KLTVCH--GKKVIHAVGPDFRKHPEAEALKLLQNAYHAVADLVNEHNIKSVAIPLLSTGI 1460
Query 1154 FGAD------PIHSLRVCVDTVRTNVYLAVFDKNLYDK------LVSSFLEMKSE 1196
+ A ++ L +D +V + DK ++ L S E+K E
Sbjct 1461 YAAGKDRLEVSLNCLTTALDRTDADVTIYCLDKKWKERIDAVLQLKESVTELKDE 1515
>sp|Q8P5Z8|Y3184_XANCP Macro domain-containing protein XCC3184
OS=Xanthomonas campestris pv. campestris (strain ATCC 33913
/ DSM 3586 / NCPPB 528 / LMG 568 / P 25) OX=190485 GN=XCC3184
PE=4 SV=1
Length=179
Score = 42.7 bits (99), Expect = 0.032, Method: Composition-based stats.
Identities = 38/127 (30%), Positives = 59/127 (46%), Gaps = 13/127 (10%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGP---LKVGGSCVLSGHNL-A 1111
V+VNAAN L GGGV GA+++A + +E+ + + P G + G +L A
Sbjct 17 VIVNAANESLLGGGGVDGAIHRAAGPRL-LEACEALPEVRPGVRCPTGEIRITDGFDLKA 75
Query 1112 KHCLHVVGPNVNKG---EDIQLLKSAYENFNQHEVLLA-----PLLSAGIFGADPIHSLR 1163
+H H VGP G E QL +++ E ++ P +S GI+G + R
Sbjct 76 RHIFHTVGPVWRDGKHNEPEQLANCYWQSLKLAEQMMLHSIAFPAISCGIYGYPLYQAAR 135
Query 1164 VCVDTVR 1170
+ V R
Sbjct 136 IAVTETR 142
>sp|Q8PHB6|Y3343_XANAC Macro domain-containing protein XAC3343
OS=Xanthomonas axonopodis pv. citri (strain 306) OX=190486
GN=XAC3343 PE=4 SV=2
Length=179
Score = 42.7 bits (99), Expect = 0.035, Method: Composition-based stats.
Identities = 40/128 (31%), Positives = 62/128 (48%), Gaps = 15/128 (12%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGP---LKVGGSCVLSGHNL-A 1111
V+VNAAN L GGGV GA+++A + +E+ + + P G + G +L A
Sbjct 17 VIVNAANESLLGGGGVDGAIHRAAGPRL-LEACEALPQVRPGVRCPTGEIRITDGFDLKA 75
Query 1112 KHCLHVVGPNVNKG---EDIQLLKSAYENFNQHEVLLA-----PLLSAGIFGADPIH-SL 1162
+H H VGP G E QL +++ E ++ P +S GI+G P+H +
Sbjct 76 RHIFHTVGPVWRDGRHNEPEQLANCYWQSLKLAEQMMLHSIAFPAISCGIYGY-PLHQAA 134
Query 1163 RVCVDTVR 1170
R+ V R
Sbjct 135 RIAVTETR 142
>sp|Q9HJ67|Y1105_THEAC Uncharacterized protein Ta1105 OS=Thermoplasma
acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062
/ NBRC 15155 / AMRC-C165) OX=273075 GN=Ta1105 PE=4 SV=2
Length=196
Score = 42.7 bits (99), Expect = 0.043, Method: Composition-based stats.
Identities = 40/128 (31%), Positives = 59/128 (46%), Gaps = 19/128 (15%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAM-----QVESDDYIATNGPLKVGGSCVLSGHNL- 1110
+VNAAN L GGGV GA++ A + ++ + Y NG L G + + G+ L
Sbjct 26 IVNAANSSLMGGGGVDGAIHSAAGPELNGELVKIRRERY--PNG-LPPGEAVITRGYRLK 82
Query 1111 AKHCLHVVGP---NVNKGEDIQLLKS------AYENFNQHEVLLAPLLSAGIFGADPIHS 1161
A H +H VGP GED L +S F H++ P LS G +G +
Sbjct 83 ASHIIHTVGPVWMGGRNGEDDVLYRSYRSCLDLAREFGIHDIAF-PALSTGAYGFPFDRA 141
Query 1162 LRVCVDTV 1169
R+ + +V
Sbjct 142 ERIAIRSV 149
>sp|Q8BCR0|POLN_RUBVN Non-structural polyprotein p200 OS=Rubella
virus (strain RN-UK86) OX=376267 PE=3 SV=1
Length=2116
Score = 44.3 bits (103), Expect = 0.056, Method: Composition-based stats.
Identities = 44/155 (28%), Positives = 64/155 (41%), Gaps = 22/155 (14%)
Query 1031 YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDY 1090
Y + V+++ DI++ K VVVNAAN L G GV GA+ A+ +
Sbjct 812 YARAAGPVHLRVRDIMDPPPGCK--VVVNAANEGLLAGSGVCGAIFANATAALAADCRRL 869
Query 1091 IATNGPLKVGGSCVLSGHNLA-KHCLHVVGPN-------VNKGEDIQLLKSAYENF---- 1138
P G + GH H +H V P + +GE LL+ AY +
Sbjct 870 ----APCPTGEAVATPGHGCGYTHIIHAVAPRRPRDPAALEEGE--ALLERAYRSIVALA 923
Query 1139 --NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
+ + PLL AG++G SLR + RT
Sbjct 924 AARRWACVACPLLGAGVYGWSAAESLRAALAATRT 958
>sp|Q6PAV8|MACD2_XENLA ADP-ribose glycohydrolase MACROD2 OS=Xenopus
laevis OX=8355 GN=macrod2 PE=2 SV=1
Length=418
Score = 43.5 bits (101), Expect = 0.069, Method: Composition-based stats.
Identities = 56/227 (25%), Positives = 100/227 (44%), Gaps = 46/227 (20%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
L + V DI + ++ +VNAAN L GGGV G +++A+ ++ E +
Sbjct 66 LCEKVSFYKGDITQ----LEVDAIVNAANTSLLGGGGVDGCIHRASGPSLLAECREL--- 118
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE----DIQLLKSAYENF------NQHE 1142
G + G + + G+ L AK+ +H VGP + +G Q L S Y + N
Sbjct 119 -GGCETGQAKITCGYELPAKYVIHTVGP-IARGHITPNHKQDLASCYNSSLTLATENDIR 176
Query 1143 VLLAPLLSAGIFGADPIHSLRVCVDTVRT----------NVYLAVF---DKNLYDKLVSS 1189
+ P +S GI+G + V + TV+ V VF D +Y + ++
Sbjct 177 TIAFPCISTGIYGYPNEPAANVALTTVKEFLKKNRDKIDRVIFCVFLEVDFKIYKRKLNE 236
Query 1190 FL--EMKSEKQVEQKIAEIPKEEVKPFITESKPS------VEQRKQD 1228
F + +++ E+ ++ KE+ TE KP ++++K+D
Sbjct 237 FFPKDGGDDEEGEKGDSDEMKED-----TEGKPQSPPMKKIKEKKED 278
>sp|Q9BQ69|MACD1_HUMAN ADP-ribose glycohydrolase MACROD1 OS=Homo
sapiens OX=9606 GN=MACROD1 PE=1 SV=2
Length=325
Score = 42.7 bits (99), Expect = 0.089, Method: Compositional matrix adjust.
Identities = 42/150 (28%), Positives = 68/150 (45%), Gaps = 24/150 (16%)
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
V +E + +L + + + +DI K++ +VNAAN L GGGV G +++A
Sbjct 135 VAVKVEEPRYKKDKQLNEKISLLRSDIT----KLEVDAIVNAANSSLLGGGGVDGCIHRA 190
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE----DIQLLKS 1133
+ D T K G + + G+ L AK+ +H VGP + GE L+S
Sbjct 191 AGPLLT----DECRTLQSCKTGKAKITGGYRLPAKYVIHTVGP-IAYGEPSASQAAELRS 245
Query 1134 AYENFNQHEVLLA--------PLLSAGIFG 1155
Y + ++LL P +S G+FG
Sbjct 246 CY--LSSLDLLLEHRLRSVAFPCISTGVFG 273
>sp|Q86924|POLN_AURAV Polyprotein P1234 OS=Aura virus OX=44158
PE=3 SV=3
Length=2499
Score = 43.9 bits (102), Expect = 0.089, Method: Compositional matrix adjust.
Identities = 55/183 (30%), Positives = 85/183 (46%), Gaps = 35/183 (19%)
Query 1043 ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGS 1102
AD EEA VVNAAN K G GV A+ K + + N +V +
Sbjct 1357 ADCTEEA-------VVNAANARGKPGDGVCRAIFKKWPKSFE---------NATTEVETA 1400
Query 1103 CVLSGHNLAKHCLHVVGPNVNK---GEDIQLLKSAYEN----FNQHEV--LLAPLLSAGI 1153
+ HN K +H VGP+ K E +LL++AY + N+ + + PLLS GI
Sbjct 1401 VMKPCHN--KVVIHAVGPDFRKYTLEEATKLLQNAYHDVAKIVNEKGISSVAIPLLSTGI 1458
Query 1154 F--GADPIH-SLR---VCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIP 1207
+ GAD + SLR +D +V + DK +++ ++ + M+ E+ E K +I
Sbjct 1459 YAAGADRLDLSLRCLFTALDRTDADVTIYCLDKK-WEQRIADAIRMR-EQVTELKDPDIE 1516
Query 1208 KEE 1210
+E
Sbjct 1517 IDE 1519
>sp|Q7MTZ7|MACRO_PORGI Macro domain-containing protein PG1779
OS=Porphyromonas gingivalis (strain ATCC BAA-308 / W83) OX=242619
GN=PG_1779 PE=2 SV=1
Length=164
Score = 41.2 bits (95), Expect = 0.11, Method: Composition-based stats.
Identities = 36/122 (30%), Positives = 59/122 (48%), Gaps = 13/122 (11%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCL 1115
+VNAAN L GGGV GA+++A + E NG G S + G+NL A++ +
Sbjct 19 IVNAANHTLLGGGGVDGAIHRAAGPELLEECR---TLNG-CPTGESKITGGYNLPAQYVI 74
Query 1116 HVVGPNVNKGE--DIQLLKSAYENF------NQHEVLLAPLLSAGIFGADPIHSLRVCVD 1167
H VGP + G+ + +LL S Y + + P +S G++ + R+ +
Sbjct 75 HTVGPVWHGGQHGEPELLASCYRTSLSIALDKGLKSIAFPCISTGVYRYPKDQAARIALA 134
Query 1168 TV 1169
T+
Sbjct 135 TI 136
>sp|P13889|POLN_RUBVT Non-structural polyprotein p200 OS=Rubella
virus (strain Therien) OX=11045 PE=3 SV=5
Length=2116
Score = 43.5 bits (101), Expect = 0.11, Method: Composition-based stats.
Identities = 44/155 (28%), Positives = 63/155 (41%), Gaps = 22/155 (14%)
Query 1031 YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDY 1090
Y + V+++ DI++ K VVVNAAN L G GV GA+ A+
Sbjct 812 YARAAGPVHLRVRDIMDPPPGCK--VVVNAANEGLLAGSGVCGAIFANATAALAANCRRL 869
Query 1091 IATNGPLKVGGSCVLSGHNLA-KHCLHVVGPN-------VNKGEDIQLLKSAYENF---- 1138
P G + GH H +H V P + +GE LL+ AY +
Sbjct 870 ----APCPTGEAVATPGHGCGYTHIIHAVAPRRPRDPAALEEGE--ALLERAYRSIVALA 923
Query 1139 --NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
+ + PLL AG++G SLR + RT
Sbjct 924 AARRWACVACPLLGAGVYGWSAAESLRAALAATRT 958
>sp|Q9ZBG3|Y6450_STRCO Macro domain-containing protein SCO6450
OS=Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
OX=100226 GN=SCO6450 PE=4 SV=1
Length=169
Score = 41.2 bits (95), Expect = 0.12, Method: Composition-based stats.
Identities = 43/148 (29%), Positives = 67/148 (45%), Gaps = 16/148 (11%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATN--GPLKVGGSCVLSGHNL-AKH 1113
+VNAAN L GGGV GA+++ A+ E A + L G + + +L A+
Sbjct 19 IVNAANSSLLGGGGVDGAIHRRGGPAILAECRRLRAGHLGKGLPTGRAVATTAGDLDARW 78
Query 1114 CLHVVGPNVNKGEDIQ-LLKSAY-ENFNQHEVLLA-----PLLSAGIFGADPIHSLRVCV 1166
+H VGP + ED LL S Y E+ + L A P +S G++ + R+ V
Sbjct 79 VIHTVGPVWSATEDRSGLLASCYRESLRTADELGARTVAFPAISTGVYRWPMDDAARIAV 138
Query 1167 DTVRTN------VYLAVFDKNLYDKLVS 1188
+TV T + +FD Y+ +
Sbjct 139 ETVATTKTSVTEIRFVLFDARAYEAFAA 166
>sp|Q8K4G6|MACD1_RAT ADP-ribose glycohydrolase MACROD1 (Fragment)
OS=Rattus norvegicus OX=10116 GN=Macrod1 PE=2 SV=2
Length=258
Score = 42.0 bits (97), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 41/150 (27%), Positives = 67/150 (45%), Gaps = 22/150 (15%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+L + + + DI K++ +VNAAN L GGGV G +++A + + D
Sbjct 82 QLNEKISLFRGDIT----KLEVDAIVNAANNSLLGGGGVDGCIHRAAGSLLT----DECR 133
Query 1093 TNGPLKVGGSCVLSGHNL-AKHCLHVVGP---NVNKGEDIQLLKSAYENFNQHEVLLA-- 1146
T + G + + G+ L AKH +H VGP L+S Y + ++LL
Sbjct 134 TLQNCETGKAKITCGYRLPAKHVIHTVGPIAVGQPTASQAAELRSCY--LSSLDLLLEHR 191
Query 1147 ------PLLSAGIFGADPIHSLRVCVDTVR 1170
P +S G+FG + V + T+R
Sbjct 192 LRSVAFPCISTGVFGYPNEEAAEVVLATLR 221
>sp|O40955|POLN_RUBVR Non-structural polyprotein p200 OS=Rubella
virus (strain RA27/3 vaccine) OX=11044 PE=1 SV=1
Length=2116
Score = 43.1 bits (100), Expect = 0.14, Method: Composition-based stats.
Identities = 44/155 (28%), Positives = 62/155 (40%), Gaps = 22/155 (14%)
Query 1031 YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDY 1090
Y + V+++ DI++ K VVVNAAN L G GV GA+ A+ +
Sbjct 812 YARAAGPVHLRVRDIMDPPPGCK--VVVNAANEGLLAGSGVCGAIFANATAALAADCRRL 869
Query 1091 IATNGPLKVGGSCVLSGHNLA-KHCLHVVGPN-------VNKGEDIQLLKSAYENFNQHE 1142
P G + GH H +H V P + +GE LL+ AY +
Sbjct 870 ----APCPTGEAVATPGHGCGYTHIIHAVAPRRPRDPAALEEGE--ALLERAYRSIVALA 923
Query 1143 VLLA------PLLSAGIFGADPIHSLRVCVDTVRT 1171
PLL AG++G SLR + RT
Sbjct 924 AARRWARVACPLLGAGVYGWSAAESLRAALAATRT 958
>sp|P03317|POLN_SINDV Polyprotein P1234 OS=Sindbis virus OX=11034
PE=1 SV=2
Length=2513
Score = 42.4 bits (98), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 50/184 (27%), Positives = 80/184 (43%), Gaps = 33/184 (18%)
Query 1043 ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGS 1102
AD EEA VVNAAN + G GV A+ K + D G ++
Sbjct 1359 ADCQEEA-------VVNAANPLGRPGEGVCRAIYKRWPTSFT----DSATETGTARMT-V 1406
Query 1103 CVLSGHNLAKHCLHVVGPNVNK---GEDIQLLKSAYEN----FNQHEV--LLAPLLSAGI 1153
C L K +H VGP+ K E ++LL++AY N+H + + PLLS GI
Sbjct 1407 C------LGKKVIHAVGPDFRKHPEAEALKLLQNAYHAVADLVNEHNIKSVAIPLLSTGI 1460
Query 1154 FGAD------PIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIP 1207
+ A ++ L +D +V + DK +++ ++ +S +++ + EI
Sbjct 1461 YAAGKDRLEVSLNCLTTALDRTDADVTIYCLDKKWKERIDAALQLKESVTELKDEDMEID 1520
Query 1208 KEEV 1211
E V
Sbjct 1521 DELV 1524
>sp|A0A1P8ASY1|JHS1_ARATH DNA replication ATP-dependent helicase/nuclease
JHS1 OS=Arabidopsis thaliana OX=3702 GN=JHS1 PE=2
SV=1
Length=1331
Score = 42.4 bits (98), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 99/443 (22%), Positives = 167/443 (38%), Gaps = 89/443 (20%)
Query 5539 TTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLN-ISDEFSSNVANYQKV- 5596
+ + N+ FV H + + P+ I P ++ I E S N Q +
Sbjct 873 SVMRFNLMQLFVQNGHNIRKMIVDLEPPRFDNGSILSQDPAISYIWSEKSLNNDQRQAIL 932
Query 5597 ---GMQKYSTLQGPPGTGKSHFAIGL--ALYYPSARIVYTACSHAAVDALCEK----ALK 5647
+ Y+ + G PGTGK+ + AL + I+ + +++AVD L K ++
Sbjct 933 KILTAKDYALILGMPGTGKTSTMVHAVKALLIRGSSILLASYTNSAVDNLLIKLKAQGIE 992
Query 5648 YLPIDKCSRIIPARARVECFDKFK------VNSTLEQYVFCTVNALPETTA-------DI 5694
+L I + + R CF + L+Q L + D+
Sbjct 993 FLRIGR-DEAVHEEVRESCFSAMNMCSVEDIKKKLDQVKVVASTCLGINSPLLVNRRFDV 1051
Query 5695 VVFDEISMATNYDLSV-VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM 5753
+ DE A L V + L A +V +GD QLP P T+ E S+ R +
Sbjct 1052 CIIDE---AGQIALPVSIGPLLFASTFVLVGDHYQLP-PLVQSTEAR-ENGMGISLFRRL 1106
Query 5754 KTIGPD---MFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSA----------------- 5793
P + R C I++ +AL+Y ++L + A
Sbjct 1107 SEAHPQAISVLQNQYRMCRG-IMELSNALIYGDRLCCGSAEVADATLVLSTSSSTSPWLK 1165
Query 5794 -----------------QCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV-F 5835
+ F+ + I + V ++I I + E L N K +
Sbjct 1166 KVLEPTRTVVFVNTDMLRAFEARDQNAINNPVEASI----IAEIVEELVNNGVDSKDIGI 1221
Query 5836 ISPYNSQNAVASKILGLPT-----QTVDSSQGSEYDYVI--FTQTTETAHSC------NV 5882
I+PYNSQ ++ +PT T+D QG + D ++ F ++ E S +
Sbjct 1222 ITPYNSQASLIQH--AIPTTPVEIHTIDKYQGRDKDCILVSFVRSREKPRSSASSLLGDW 1279
Query 5883 NRFNVAITRAKVGILCIMSDRDL 5905
+R NVA+TRAK ++ + S R L
Sbjct 1280 HRINVALTRAKKKLIMVGSQRTL 1302
>sp|O28751|Y1521_ARCFU ADP-ribose glycohydrolase AF_1521 OS=Archaeoglobus
fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628
/ NBRC 100126 / VC-16) OX=224325 GN=AF_1521 PE=1 SV=2
Length=192
Score = 40.4 bits (93), Expect = 0.24, Method: Composition-based stats.
Identities = 43/152 (28%), Positives = 68/152 (45%), Gaps = 30/152 (20%)
Query 1057 VVNAANVYLKHGGGVAGALNKA-----------TNNAMQVE-SDDYIATNGPLKVGGSCV 1104
+VNAAN L+HGGGVA A+ KA + AM+ + DYI +G + V +
Sbjct 29 IVNAANKRLEHGGGVAYAIAKACAGDAGLYTEISKKAMREQFGRDYI-DHGEVVVTPAMN 87
Query 1105 LSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF---------NQHEVLLAPLLSAGIFG 1155
L + K+ H VGP + +L + Y+ F E + P +SAGI+G
Sbjct 88 LEERGI-KYVFHTVGPICSGMWSEELKEKLYKAFLGPLEKAEEMGVESIAFPAVSAGIYG 146
Query 1156 ADPIHSLRVCVDTVRT-------NVYLAVFDK 1180
D + ++ V+ V L ++D+
Sbjct 147 CDLEKVVETFLEAVKNFKGSAVKEVALVIYDR 178
>sp|Q306W6|POLN_EEEV1 Polyprotein P1234 OS=Eastern equine encephalitis
virus (strain PE-0.0155) OX=374596 PE=1 SV=3
Length=2471
Score = 42.4 bits (98), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 49/183 (27%), Positives = 75/183 (41%), Gaps = 48/183 (26%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHC- 1114
V+VNAAN + G GV GAL K A P+ G + +L KH
Sbjct 1345 VIVNAANNKGQPGAGVCGALYKKWPGAFD---------KAPIATGTA------HLVKHTP 1389
Query 1115 --LHVVGPNVNKGEDI---QLLKSAYE------NFNQHEVLLAPLLSAGIF--GADPI-- 1159
+H VGPN ++ ++ Q L Y N ++ + PLLS G++ G D +
Sbjct 1390 NIIHAVGPNFSRMSEVEGNQKLSEVYMDIAKIINKERYNKVSIPLLSTGVYAGGKDRVMQ 1449
Query 1160 --HSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITE 1217
+ L +DT +V + DK E +++ IA KE V+ + +
Sbjct 1450 SLNHLFTAMDTTDADVTIYCLDKQW-------------ETRIKDAIAR--KESVEELVED 1494
Query 1218 SKP 1220
KP
Sbjct 1495 DKP 1497
>sp|Q44020|YGB2_CUPNE Macro domain-containing protein in gbd 3'region
OS=Cupriavidus necator OX=106590 PE=4 SV=1
Length=173
Score = 40.0 bits (92), Expect = 0.27, Method: Composition-based stats.
Identities = 39/109 (36%), Positives = 58/109 (53%), Gaps = 11/109 (10%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCL 1115
+VNAAN L GGGV GA++ A +A++ T G G + + +G +L A + +
Sbjct 21 IVNAANSGLLGGGGVDGAIHGAGGSAIKEACRAIRDTQGGCPTGEAVITTGGHLPAPYVI 80
Query 1116 HVVGP---NVNKGEDIQLLKSAYEN----FNQHEV--LLAPLLSAGIFG 1155
H VGP ++GED +LL +AY N QH + L P +S GI+
Sbjct 81 HAVGPVWQGGDQGED-ELLANAYRNSIRLAAQHHLRRLAFPNISTGIYA 128
>sp|Q9YBE9|Y1648_AERPE Uncharacterized protein APE_1648.1 OS=Aeropyrum
pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 /
NBRC 100138 / K1) OX=272557 GN=APE_1648.1 PE=4 SV=2
Length=189
Score = 40.0 bits (92), Expect = 0.33, Method: Composition-based stats.
Identities = 24/67 (36%), Positives = 37/67 (55%), Gaps = 5/67 (7%)
Query 1051 KVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL 1110
KV+ VVN AN + GGG AGAL +A + ++ E+ P+ VG + + SG +L
Sbjct 20 KVRAEAVVNPANSLMIMGGGAAGALKRAGGSVIEEEA----MRKAPVPVGEAVITSGGSL 75
Query 1111 -AKHCLH 1116
A+ +H
Sbjct 76 PARFVIH 82
>sp|Q2KHU5|MACD1_BOVIN ADP-ribose glycohydrolase MACROD1 OS=Bos
taurus OX=9913 GN=MACROD1 PE=2 SV=1
Length=325
Score = 40.8 bits (94), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 41/148 (28%), Positives = 67/148 (45%), Gaps = 20/148 (14%)
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
V +E + +L + + + DI K++ +VNAAN L GGGV G +++A
Sbjct 135 VTVKVEEPKYKKDKQLNEKISLFRGDIT----KLEVDAIVNAANSSLLGGGGVDGCIHRA 190
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE----DIQLLKS 1133
+ D T + G + + G+ L AK+ +H VGP + GE L+S
Sbjct 191 AGPLLT----DECRTLQNCETGKAKITCGYRLPAKYVIHTVGP-IAHGEPSASQAAELRS 245
Query 1134 AY----ENFNQHEVLLA--PLLSAGIFG 1155
Y + +H + A P +S G+FG
Sbjct 246 CYLSSLDLLLEHRLRSAAFPCISTGVFG 273
>sp|Q9BYK8|HELZ2_HUMAN 3'-5' exoribonuclease HELZ2 OS=Homo sapiens
OX=9606 GN=HELZ2 PE=1 SV=7
Length=2896
Score = 41.2 bits (95), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 28/91 (31%), Positives = 44/91 (48%), Gaps = 25/91 (27%)
Query 5836 ISPYNSQNAVASKIL------GLPTQTVDSSQGSEYDYVIFTQTTETAHS---------- 5879
++PYN+Q + SK L G+ ++ SQGSE+ YV+ + A S
Sbjct 2768 LTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSW 2827
Query 5880 --------CNVNRFNVAITRAKVGILCIMSD 5902
+ N+ NVA+TRA+ G LC++ D
Sbjct 2828 LKKFLGFVVDPNQVNVAVTRAQEG-LCLIGD 2857
>sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens
OX=9606 GN=SETX PE=1 SV=4
Length=2677
Score = 41.2 bits (95), Expect = 0.58, Method: Compositional matrix adjust.
Identities = 61/242 (25%), Positives = 97/242 (40%), Gaps = 45/242 (19%)
Query 5716 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV----CRLMK--------TIGPDMFLG 5763
R + +GDP QLP T+++ E Y S+ CRL++ + P + L
Sbjct 2198 RCNKLILVGDPKQLPP--TVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQLT 2255
Query 5764 TCRRCPAEIVDTVSALVYDNKLKAHKDKSA---------QCFKMFY--KGVITHDVSSAI 5812
R +I S VY+ LK ++ A Q + +F G D S I
Sbjct 2256 VQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYI 2315
Query 5813 NRPQIGVVREFLT------RNPAWRKAVFISPYNSQNAVASKILGL------PTQ--TVD 5858
N +I +V E + ++ ++R I+ Y +Q + K L P + TVD
Sbjct 2316 NVQEIKLVMEIIKLIKDKRKDVSFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVD 2375
Query 5859 SSQGSEYDYVIFTQTTETAHS------CNVNRFNVAITRAKVGILCIMSDRDLYDKLQFT 5912
+ QG + D VI T + ++ R NV ITRAK + + R L + +
Sbjct 2376 AFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWN 2435
Query 5913 SL 5914
L
Sbjct 2436 QL 2437
>sp|P13896|POLN_WEEV Polyprotein P1234 OS=Western equine encephalitis
virus OX=11039 PE=3 SV=3
Length=2467
Score = 41.2 bits (95), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 44/157 (28%), Positives = 66/157 (42%), Gaps = 33/157 (21%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKH--- 1113
+VNAAN + G GV GAL + A + P+ VG + L KH
Sbjct 1346 IVNAANSKGQPGSGVCGALYRKWPAAFDRQ---------PIAVGTA------RLVKHEPL 1390
Query 1114 CLHVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVLLAPLLSAGIF--GADPI--- 1159
+H VGPN +K + + L +AY N + + PLLS GI+ G D +
Sbjct 1391 IIHAVGPNFSKMPEPEGDLKLAAAYMSIASIVNAERITKISVPLLSTGIYSGGKDRVMQS 1450
Query 1160 -HSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKS 1195
H L DT +V + DK +++ + +S
Sbjct 1451 LHHLFTAFDTTDADVTIYCLDKQWETRIIEAIHRKES 1487
>sp|P18479|POLG_ZYMVC Genome polyprotein OS=Zucchini yellow mosaic
virus (strain California) OX=117128 PE=1 SV=2
Length=3080
Score = 41.2 bits (95), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 57/270 (21%), Positives = 110/270 (41%), Gaps = 48/270 (18%)
Query 4846 DYYRYNLP---TMCDIRQLLFVVEVVDKY---FDCYDGGCINANQVIVNNLDKSAGFPFN 4899
D+++YN P D + L V+ V + F+ + I + I N+L+ A
Sbjct 2356 DFFKYNKPVTVNQLDHDKFLGAVDGVIRMMCDFEFNECRFITDPEEIYNSLNMKAAIGAQ 2415
Query 4900 KWGKARLYYDSMS-YEDQDALFAYTKR--NVIPTITQMNLKYAISAKNRAR--------- 4947
GK + Y++ + ++ + LF +R N + +LK + + R
Sbjct 2416 YRGKKKEYFEGLDDFDRERLLFQSCERLFNGYKGLWNGSLKAELRPLEKVRANKTRTFTA 2475
Query 4948 ----TVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVEN 5003
T+ G +C N +F++K LK +G +KFYGGW +++++
Sbjct 2476 APIDTLLGAKVCVDDFNNEFYRKNLK-------CPWTVGMTKFYGGWDKLMRSLPD---- 2524
Query 5004 PHLMGWDYPKCDRAM------PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSE 5057
GW Y D + P +L A L++ + + L N A+++
Sbjct 2525 ----GWLYCHADGSQFDSSLTPALLN--AVLIIRSFYMEDWWVGQEM--LENLYAEIVYT 2576
Query 5058 MVMC-GGSLYVKPGGTSSGDATTAYANSVF 5086
++ G+++ K G +SG +T N++
Sbjct 2577 PILAPDGTIFKKFRGNNSGQPSTVVDNTLM 2606
>sp|Q9HEH1|RENT1_NEUCR Regulator of nonsense transcripts 1 homolog
OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A /
CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=2E4.130 PE=3
SV=1
Length=1093
Score = 40.8 bits (94), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 28/87 (32%), Positives = 46/87 (53%), Gaps = 9/87 (10%)
Query 5561 APTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLA 5620
APT + + GL P LN +S +A ++V S +QGPPGTGK+ + +
Sbjct 438 APTKITMPKKFHVPGL-PELN-----ASQIAAIKQVLSNPLSLIQGPPGTGKTVTSATII 491
Query 5621 LY---YPSARIVYTACSHAAVDALCEK 5644
+ +++++ A S+ AVD LCE+
Sbjct 492 YHLAKMSNSQVLVCAPSNVAVDQLCER 518
>sp|Q9VHM2|VP35L_DROME VPS35 endosomal protein sorting factor-like
OS=Drosophila melanogaster OX=7227 GN=CG8202 PE=2 SV=3
Length=942
Score = 40.8 bits (94), Expect = 0.68, Method: Compositional matrix adjust.
Identities = 28/97 (29%), Positives = 44/97 (45%), Gaps = 13/97 (13%)
Query 3702 DDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLA------ 3755
DD R++ L+NV ++KV++GN L+Q +S + SN V T++ A
Sbjct 609 DDERRQIAQLINVF--IHKVHFGNDLEQQLSFYVEARGTFSNLDAVYVTLVHAACKLATR 666
Query 3756 -----RGIVFMCVEYCPIFFITGNTLQCIMLVYCFLG 3787
G V C+ YC I + +Q M +Y G
Sbjct 667 NRSKSTGFVKACIAYCFITIPSIEAVQQQMNLYLLCG 703
>sp|Q09449|YQ12_CAEEL Uncharacterized ATP-dependent helicase C05C10.2
OS=Caenorhabditis elegans OX=6239 GN=C05C10.2 PE=3 SV=2
Length=1523
Score = 40.8 bits (94), Expect = 0.71, Method: Compositional matrix adjust.
Identities = 56/204 (27%), Positives = 84/204 (41%), Gaps = 35/204 (17%)
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMF----LGTCRRCPAEIVDTVSA 5778
IGD QLP +G L+ F + + I MF L RC + + +S
Sbjct 1206 IGDIHQLPPYCEEGLEGKLKD--FGIGNTMERAIKEKMFPVCTLRNVYRCHPKTTELLSE 1263
Query 5779 LVYDNKLKAHKDKSAQC--------------FKMFY---KGVITHDVSSAINRPQIGVVR 5821
L YD L + + A+ F M + G T +S N + +V
Sbjct 1264 LFYDGALVSGVSELARSDFMTKRDDFWPNPKFPMMFVNNTGASTKMGTSTSNSSEKSIVG 1323
Query 5822 EFLT------RNPAWRKAV-FISPYNSQNAVASKIL---GLPTQTVDSSQGSEYDYVIFT 5871
E + RNP + IS Y++Q ++ ++ L G+ TVD+ QGSE + +I
Sbjct 1324 EIVQNLINDPRNPVNPSDIGVISFYSAQTSILTEHLRGSGVKCGTVDAFQGSEKEIIIMC 1383
Query 5872 QTTETAHSCN--VNRFNVAITRAK 5893
T E NR NVA++RAK
Sbjct 1384 STNERISDFMQLSNRLNVAMSRAK 1407
>sp|A2AKX3|SETX_MOUSE Probable helicase senataxin OS=Mus musculus
OX=10090 GN=Setx PE=1 SV=1
Length=2646
Score = 40.4 bits (93), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 62/242 (26%), Positives = 101/242 (42%), Gaps = 45/242 (19%)
Query 5716 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV----CRLMKT------IG--PDMFLG 5763
R + +GDP QLP T+++ E Y S+ C+L++ IG P + L
Sbjct 2174 RCNKLILVGDPKQLPP--TVISMKAQEYGYDQSMMARFCKLLEENVEQNMIGRLPVLQLT 2231
Query 5764 TCRRCPAEIVDTVSALVYDNKLKAHK-DKSAQC-----FKMFY-----KGVITHDVSSAI 5812
R +I S VY+ LK ++ +S +C F+ + G D S I
Sbjct 2232 IQYRMHPDICLFPSNYVYNKNLKTNRLTESIRCSSEWPFQPYLVFDVGDGSERRDNDSYI 2291
Query 5813 NRPQIGVVREFLT------RNPAWRKAVFISPYNSQNAVASKILGL------PTQ--TVD 5858
N +I +V E + ++ ++R I+ Y +Q + K L P + TVD
Sbjct 2292 NVQEIKLVMEIIKLIKEKRKDISFRNIGIITHYKAQKTMIQKDLEKEFDKKGPAEVDTVD 2351
Query 5859 SSQGSEYDYVIFTQTTETAHS------CNVNRFNVAITRAKVGILCIMSDRDLYDKLQFT 5912
+ QG + D +I T +A ++ R NV ITRAK + + R L + +
Sbjct 2352 AFQGRQKDCIIVTCVRASAVQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWY 2411
Query 5913 SL 5914
L
Sbjct 2412 EL 2413
>sp|Q9FJR0|RENT1_ARATH Regulator of nonsense transcripts 1 homolog
OS=Arabidopsis thaliana OX=3702 GN=UPF1 PE=1 SV=2
Length=1254
Score = 40.4 bits (93), Expect = 0.98, Method: Compositional matrix adjust.
Identities = 33/119 (28%), Positives = 56/119 (47%), Gaps = 18/119 (15%)
Query 5803 VITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKIL--GLPTQTVDSS 5860
++T + S + QIGV+ P + +I Y ++N + L + +VDS
Sbjct 796 LVTAFLKSGVVPSQIGVI------TPYEGQRAYIVNYMARNGSLRQQLYKEIEVASVDSF 849
Query 5861 QGSEYDYVIFTQTTETAHSC-----NVNRFNVAITRAKVGILC-----IMSDRDLYDKL 5909
QG E DY+I + H + R NVA+TRA+ GI+ ++S + L++ L
Sbjct 850 QGREKDYIILSCVRSNEHQGIGFLNDPRRLNVALTRARYGIVILGNPKVLSKQPLWNGL 908
>sp|Q922B1|MACD1_MOUSE ADP-ribose glycohydrolase MACROD1 OS=Mus
musculus OX=10090 GN=Macrod1 PE=1 SV=2
Length=323
Score = 39.7 bits (91), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 39/150 (26%), Positives = 67/150 (45%), Gaps = 22/150 (15%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+L + + + DI K++ +VNAAN L GGGV G +++A + + D
Sbjct 147 QLNEKISLYRGDIT----KLEVDAIVNAANSSLLGGGGVDGCIHRAAGSLLT----DECR 198
Query 1093 TNGPLKVGGSCVLSGHNL-AKHCLHVVGP---NVNKGEDIQLLKSAYENFNQHEVLLA-- 1146
T + G + + G+ L AK+ +H VGP L+S Y + ++LL
Sbjct 199 TLQNCETGKAKITCGYRLPAKYVIHTVGPIAVGQPTASQAAELRSCY--LSSLDLLLEHR 256
Query 1147 ------PLLSAGIFGADPIHSLRVCVDTVR 1170
P +S G+FG + V + ++R
Sbjct 257 LRSVAFPCISTGVFGYPNEEAAEVVLASLR 286
>sp|P32644|ECM32_YEAST Putative ATP-dependent RNA helicase ECM32
OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=ECM32 PE=1 SV=1
Length=1121
Score = 40.0 bits (92), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 26/63 (41%), Positives = 35/63 (56%), Gaps = 5/63 (8%)
Query 5842 QNAVASKILGLPTQTVDSSQGSEYDYVIFT---QTTETAHS--CNVNRFNVAITRAKVGI 5896
QN V + I GL TVDS QG E ++IF+ TE + R NVA+TRAK G+
Sbjct 1026 QNNVINIINGLHVATVDSFQGHEKSFIIFSCVRNNTENKIGFLRDKRRLNVALTRAKHGL 1085
Query 5897 LCI 5899
+ +
Sbjct 1086 IVV 1088
>sp|Q306W8|POLN_EEEV8 Polyprotein P1234 OS=Eastern equine encephalitis
virus (strain PE-3.0815) OX=374597 PE=1 SV=3
Length=2474
Score = 40.0 bits (92), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 49/182 (27%), Positives = 74/182 (41%), Gaps = 48/182 (26%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHC-- 1114
+VNAAN + G GV GAL K A P+ G + +L KH
Sbjct 1346 IVNAANNKGQPGAGVCGALYKKWPGAFD---------KVPIATGTA------HLVKHTPN 1390
Query 1115 -LHVVGPNVNKGEDI---QLLKSAYE------NFNQHEVLLAPLLSAGIF--GADPI--- 1159
+H VGPN ++ ++ Q L Y N ++ + PLLS GI+ G D +
Sbjct 1391 IIHAVGPNFSRVSEVEGNQKLSEVYMDIAKIINRERYNKVSIPLLSTGIYAGGKDRVMQS 1450
Query 1160 -HSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITES 1218
+ L +DT +V + DK E +++ IA KE V+ + +
Sbjct 1451 LNHLFTAMDTTDADVTIYCLDKQW-------------EARIKDAIAR--KESVEELVEDD 1495
Query 1219 KP 1220
KP
Sbjct 1496 KP 1497
>sp|Q9HXU7|Y3693_PSEAE Macro domain-containing protein PA3693
OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP
104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964
GN=PA3693 PE=4 SV=1
Length=173
Score = 38.1 bits (87), Expect = 1.3, Method: Composition-based stats.
Identities = 37/112 (33%), Positives = 51/112 (46%), Gaps = 21/112 (19%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL---KVGGSCVLSGHNL-AK 1112
+VNAAN L GGGV GA+++A + +A L K G + + G L A
Sbjct 19 IVNAANSSLLGGGGVDGAIHRAAGAEL-------VAACRLLHGCKTGEAKITRGFRLPAA 71
Query 1113 HCLHVVGPNVNKGE--DIQLLKSAY-------ENFNQHEVLLAPLLSAGIFG 1155
H +H VGP G+ + +LL S Y E V P +S GI+G
Sbjct 72 HVIHTVGPVWRGGDNGEAELLASCYRRSLALAEQAGAASVAF-PAISCGIYG 122
>sp|Q09820|RENT1_SCHPO ATP-dependent helicase upf1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=upf1
PE=3 SV=2
Length=925
Score = 39.7 bits (91), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 33/127 (26%), Positives = 56/127 (44%), Gaps = 25/127 (20%)
Query 5798 MFYKGVITHDVSSA----INRPQIG----VVREFLTRNPAWRKAVFISPYNSQ------- 5842
MFY ++S++ +NR + +V FL N + ++PY+ Q
Sbjct 675 MFYANFGQEELSASGTSFLNRTEASTCEKIVTTFLRSNVLPEQIGIVTPYDGQRSYIVQY 734
Query 5843 ---NAVASKIL--GLPTQTVDSSQGSEYDYVIFTQTTETAHSC-----NVNRFNVAITRA 5892
N K L + +VD+ QG E D++I + + H + R NVA+TRA
Sbjct 735 MQNNGSMQKDLYKAVEVASVDAFQGREKDFIILSCVRSSEHQGIGFVNDPRRLNVALTRA 794
Query 5893 KVGILCI 5899
K G++ +
Sbjct 795 KYGVIVL 801
>sp|Q98TR3|RENT1_TAKRU Putative regulator of nonsense transcripts
1 OS=Takifugu rubripes OX=31033 GN=rent1 PE=3 SV=1
Length=1097
Score = 38.5 bits (88), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 30/122 (25%), Positives = 53/122 (43%), Gaps = 20/122 (16%)
Query 5804 ITHDVSSAINRPQIGVVREFLTR----NPAWRKAVFISPYNSQ-----------NAVASK 5848
I +S +NR + V + TR + I+PY Q ++ +K
Sbjct 738 IASSGTSYLNRTEAANVEKITTRLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTK 797
Query 5849 ILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC-----NVNRFNVAITRAKVGILCIMSDR 5903
+ + +VD+ QG E D++I + H + R NVA+TRAK G++ + + +
Sbjct 798 LYQVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRAKYGVIIVGNPK 857
Query 5904 DL 5905
L
Sbjct 858 AL 859
>sp|Q9RUV0|PPDE_DEIRA Phosphatase/phosphodiesterase DR_1281 OS=Deinococcus
radiodurans (strain ATCC 13939 / DSM 20539 / JCM
16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 /
VKM B-1422 / R1) OX=243230 GN=DR_1281 PE=1 SV=1
Length=255
Score = 37.7 bits (86), Expect = 3.1, Method: Composition-based stats.
Identities = 37/110 (34%), Positives = 47/110 (43%), Gaps = 21/110 (19%)
Query 2858 ITREVGFVVPGLPGTILRT--TNGDFL---HFLPRVF-SAVGNICYTPSKLIEYTDFATS 2911
I R + + PG PG RT NG+ L + L RVF AV N T L+E D T
Sbjct 84 IVRPLNYADPGTPGVGWRTFDVNGEKLTVVNLLGRVFMEAVDNPFRTMDALLERDDLGTV 143
Query 2912 ACVLAAECTIFKDASG--------------KPVPYCYDTNVLEGSVAYES 2947
AE T K+A G VP DT +L+G AY++
Sbjct 144 FVDFHAEATSEKEAMGWHLAGRVAAVIGTHTHVPTA-DTRILKGGTAYQT 192
>sp|Q06502|RPOA_LDVC Replicase polyprotein 1ab OS=Lactate dehydrogenase
elevating virus (strain C) OX=300015 GN=rep PE=3 SV=2
Length=3637
Score = 38.5 bits (88), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 58/250 (23%), Positives = 101/250 (40%), Gaps = 32/250 (13%)
Query 4912 SYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKS- 4970
S+ D DAL + T+T LK +K + RT+ G + + R + +
Sbjct 2527 SHPDIDALCERACKEHWQTVTPCTLKKQYCSKAKTRTILGTNNFVALGLRSALSGVTQGF 2586
Query 4971 IAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMAS--- 5027
+ G+ + +G +KF L T S + D CDR+ P ++R +
Sbjct 2587 MRKGIGSPICLGKNKF-----TPLPTKVSG----RCLEADLASCDRSTPAIIRWFTTNLL 2637
Query 5028 LVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFN 5087
LA S + N C +S M C + K GG SSGD T+ +N+V++
Sbjct 2638 FELAGPEEWIPSY------VLNCCHDAVSTMSGC----FDKRGGLSSGDPVTSVSNTVYS 2687
Query 5088 ICQAVTANVNALLSTDGNKIADKYVRNL--QHRLYE----CLYRNRDVDTDFVNEF--YA 5139
+ V + G+K+ ++R+ +L+E +Y + V D +E Y
Sbjct 2688 LVIYAQHMVLSAFRC-GHKVGGLFLRDSLEMEQLFELQPLLVYSDDVVLYDESSELPNYH 2746
Query 5140 YLRKHFSMMI 5149
+ H +M+
Sbjct 2747 FFVDHLDLML 2756
>sp|P18478|POLG_WMV2U Genome polyprotein (Fragment) OS=Watermelon
mosaic virus II (isolate USA) OX=148360 PE=1 SV=3
Length=1017
Score = 38.5 bits (88), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 59/269 (22%), Positives = 109/269 (41%), Gaps = 46/269 (17%)
Query 4846 DYYRYNLPTM---CDIRQLLFVVE-VVDKYFDCYDGGC--INANQVIVNNLDKSAGFPFN 4899
D+++YN P + D VE V+ D C + I +L+ A
Sbjct 291 DFFKYNKPVVLNEVDFNAFEKAVEGVITMMVDFEFAECLFVTDPDEIYGSLNMKAAVGAQ 350
Query 4900 KWGKARLYYDSM-SYEDQDALFAYTKR--NVIPTITQMNLKYAIS-----AKNRART--- 4948
GK + Y+ M S++ + L+ +R N I +LK + N+ RT
Sbjct 351 YKGKKQDYFSGMDSFDKERLLYLSCERLFNGEKGIWNGSLKAELRPIEKVQANKTRTFTA 410
Query 4949 -----VAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVEN 5003
+ G +C N QF+ LK +G +KFYGGW +++++
Sbjct 411 APLDTLLGAKVCVDDFNNQFYSFNLK-------CPWTVGMTKFYGGWDKLMRSLPD---- 459
Query 5004 PHLMGWDYPKCDRAM--PNMLRIMASLVLARKHTTCCSLSHRFY---RLANECAQVLSEM 5058
GW Y D + ++ ++ + VL+ + CC + + L N A+++
Sbjct 460 ----GWTYCHADGSQFDSSLTPLLLNAVLSIR---CCFMEDWWVGREMLENLYAEIVYTP 512
Query 5059 VMC-GGSLYVKPGGTSSGDATTAYANSVF 5086
++ G+++ K G +SG +T N++
Sbjct 513 ILAPDGTIFKKFRGNNSGQPSTVVDNTLM 541
>sp|Q54I89|RENT1_DICDI Regulator of nonsense transcripts 1 OS=Dictyostelium
discoideum OX=44689 GN=upf1 PE=3 SV=1
Length=1331
Score = 38.5 bits (88), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 54/244 (22%), Positives = 102/244 (42%), Gaps = 43/244 (18%)
Query 5695 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK 5754
++ DE + A+ + ++ + AK + +GD QL P LL K ++ S+ +
Sbjct 703 ILIDESTQASEPEC-LIPLMMGAKQVILVGDHRQL-GP-VLLCKKVVDAGLSQSLFERLI 759
Query 5755 TIG--PDMFLGTCRRCPAEIVDTVSALVYDNKLKA---HKDKSAQCF---------KMFY 5800
++G P+ R P+ + + S Y+ +L + H D+ +Q F+
Sbjct 760 SLGHHPERLTIQYRMHPS-LTEFPSNTSYEGQLVSELSHTDRDSQSKFPWPQPKDPMFFF 818
Query 5801 KGVITHDVSSA----INRPQIGV----VREFLTRNPAWRKAVFISPYNSQNAVASKIL-- 5850
+ ++SS+ IN + + V +FL + I+PY Q A + +
Sbjct 819 NCTGSEEISSSGTSFINTTEASICEKIVTKFLELGSLPGQIGIITPYEGQRAYITSHMQK 878
Query 5851 ----------GLPTQTVDSSQGSEYDYVIFTQTTETAHSC-----NVNRFNVAITRAKVG 5895
+ +VDS QG E DY+I + + + R NVA+TRA+ G
Sbjct 879 SGKLNLELYKSIEVASVDSFQGREKDYIILSCVRSNDYQGIGFLQDPRRLNVALTRARFG 938
Query 5896 ILCI 5899
++ +
Sbjct 939 LIIL 942
>sp|Q99IE5|POLN_RUBVV Non-structural polyprotein p200 OS=Rubella
virus (strain TO-336) OX=376264 PE=3 SV=1
Length=2116
Score = 38.5 bits (88), Expect = 3.4, Method: Composition-based stats.
Identities = 41/153 (27%), Positives = 62/153 (41%), Gaps = 22/153 (14%)
Query 1017 TPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALN 1076
TP + + Y + V+++ DI++ K VVVNAAN L G GV GA+
Sbjct 798 TPTKADPDSDIVESYARAAGPVHLRVRDIMDPPPGCK--VVVNAANEGLLAGSGVCGAIF 855
Query 1077 KATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA-KHCLHVVGPN-------VNKGEDI 1128
A+ + P G + GH H +H V P + +GE
Sbjct 856 ANATAALAADCRRL----APCPTGEAVATPGHGCGYTHIIHAVAPRRPRDPAALEEGE-- 909
Query 1129 QLLKSAYENF------NQHEVLLAPLLSAGIFG 1155
LL+ AY + + + PLL AG++G
Sbjct 910 ALLERAYRSIVALAAARRWACVACPLLGAGVYG 942
>sp|Q99IE7|POLN_RUBVO Non-structural polyprotein p200 OS=Rubella
virus (strain TO-336 vaccine) OX=376265 PE=3 SV=1
Length=2116
Score = 38.5 bits (88), Expect = 3.4, Method: Composition-based stats.
Identities = 41/153 (27%), Positives = 62/153 (41%), Gaps = 22/153 (14%)
Query 1017 TPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALN 1076
TP + + Y + V+++ DI++ K VVVNAAN L G GV GA+
Sbjct 798 TPTKADPDSDIVESYARAAGPVHLRVRDIMDPPPGCK--VVVNAANEGLLAGSGVCGAIF 855
Query 1077 KATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA-KHCLHVVGPN-------VNKGEDI 1128
A+ + P G + GH H +H V P + +GE
Sbjct 856 ANATAALAADCRRL----APCPTGEAVATPGHGCGYTHIIHAVAPRRPRDPAALEEGE-- 909
Query 1129 QLLKSAYENF------NQHEVLLAPLLSAGIFG 1155
LL+ AY + + + PLL AG++G
Sbjct 910 ALLERAYRSIVALAAARRWACVACPLLGAGVYG 942
>sp|Q4QXJ8|POLN_EEEVF Polyprotein P1234 OS=Eastern equine encephalitis
virus (strain Florida 91-469) OX=374598 PE=1 SV=3
Length=2494
Score = 38.5 bits (88), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 43/167 (26%), Positives = 71/167 (43%), Gaps = 39/167 (23%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKH-- 1113
V+VNAAN + G GV GAL + A + P+ G + +L KH
Sbjct 1345 VIVNAANNKGQPGSGVCGALYRKWPGAFDKQ---------PVATGKA------HLVKHSP 1389
Query 1114 -CLHVVGPN---VNKGEDIQLLKSAY---------ENFNQHEVLLAPLLSAGIF--GADP 1158
+H VGPN +++ E Q L Y E F + + PLLS GI+ G D
Sbjct 1390 NVIHAVGPNFSRLSENEGDQKLSEVYMDIARIINNERFTKVSI---PLLSTGIYAGGKDR 1446
Query 1159 I----HSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQ 1201
+ + L +DT ++ + DK ++ + +S +++ +
Sbjct 1447 VMQSLNHLFTAMDTTDADITIYCLDKQWESRIKEAITRKESVEELTE 1493
>sp|Q9KHE2|Y189_STRGR Macro domain-containing protein in non 5'region
OS=Streptomyces griseus OX=1911 PE=4 SV=1
Length=177
Score = 36.6 bits (83), Expect = 3.7, Method: Composition-based stats.
Identities = 43/145 (30%), Positives = 62/145 (43%), Gaps = 17/145 (12%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT--NGPLKVGGSCVLSGHNL-AK 1112
V+VNAAN L GGGV GA+++ + + A+ L G + + L A+
Sbjct 23 VIVNAANSSLLGGGGVDGAIHRRGGPDILAACRELRASRYGKGLPTGQAVATTAGRLDAR 82
Query 1113 HCLHVVGPNVNKGEDIQ-LLKSAY-ENFNQHEVLLA-----PLLSAGIFGADPIHSLRVC 1165
+H VGP + +D LL S Y E+ L A P +S GI+G R+
Sbjct 83 WIVHTVGPVFSGAQDRSALLASCYRESLRLAAELGARSIAFPAISTGIYGWPMDDGARIA 142
Query 1166 VDTVRT-------NVYLAVFDKNLY 1183
V TV V +FD + Y
Sbjct 143 VRTVLAETVEPVEEVRFVLFDAHAY 167
>sp|O76512|RENT1_CAEEL Regulator of nonsense transcripts 1 OS=Caenorhabditis
elegans OX=6239 GN=smg-2 PE=1 SV=1
Length=1069
Score = 38.1 bits (87), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 29/113 (26%), Positives = 55/113 (49%), Gaps = 16/113 (14%)
Query 5808 VSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKIL-GLPTQTVDSSQGSEYD 5866
+ + + QIGV+ + +++ ++ ++Q + SK+ + +VD+ QG E D
Sbjct 755 IKAGVQPHQIGVITSY-----EGQRSFIVNYMHTQGTLNSKLYENVEIASVDAFQGREKD 809
Query 5867 YVIFTQTTET-----AHSCNVNRFNVAITRAKVGILC-----IMSDRDLYDKL 5909
Y+I T + R NVAITRAK G++ +++ DL+ +L
Sbjct 810 YIIVTCVRSNDILGIGFLSDPRRLNVAITRAKYGLVLVGNAKVLARHDLWHEL 862
>sp|Q7TZB9|Y1934_MYCBO Uncharacterized protein Mb1934c OS=Mycobacterium
bovis (strain ATCC BAA-935 / AF2122/97) OX=233413
GN=lppD PE=4 SV=1
Length=358
Score = 37.7 bits (86), Expect = 4.0, Method: Composition-based stats.
Identities = 24/83 (29%), Positives = 44/83 (53%), Gaps = 6/83 (7%)
Query 1036 DNVYIKNADIVE-EAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATN 1094
DNV + ++ + + K++ + NAAN L+H GGVA A+ +A +Q ES +
Sbjct 184 DNVSMIELEVHQADVTKLELDAITNAANTRLRHAGGVAAAIARAGGPELQRESTE----K 239
Query 1095 GPLKVGGSC-VLSGHNLAKHCLH 1116
P+ +G + +G A++ +H
Sbjct 240 APIGLGEAVETTAGDMPARYVIH 262
>sp|P9WK29|Y1899_MYCTU Uncharacterized protein Rv1899c OS=Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv) OX=83332
GN=Rv1899c PE=1 SV=1
Length=359
Score = 37.7 bits (86), Expect = 4.0, Method: Composition-based stats.
Identities = 24/83 (29%), Positives = 44/83 (53%), Gaps = 6/83 (7%)
Query 1036 DNVYIKNADIVE-EAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATN 1094
DNV + ++ + + K++ + NAAN L+H GGVA A+ +A +Q ES +
Sbjct 185 DNVSMIELEVHQADVTKLELDAITNAANTRLRHAGGVAAAIARAGGPELQRESTE----K 240
Query 1095 GPLKVGGSC-VLSGHNLAKHCLH 1116
P+ +G + +G A++ +H
Sbjct 241 APIGLGEAVETTAGDMPARYVIH 263
>sp|P9WK28|Y1899_MYCTO Uncharacterized protein MT1950 OS=Mycobacterium
tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=MT1950
PE=4 SV=1
Length=374
Score = 37.7 bits (86), Expect = 4.1, Method: Composition-based stats.
Identities = 24/83 (29%), Positives = 44/83 (53%), Gaps = 6/83 (7%)
Query 1036 DNVYIKNADIVE-EAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATN 1094
DNV + ++ + + K++ + NAAN L+H GGVA A+ +A +Q ES +
Sbjct 200 DNVSMIELEVHQADVTKLELDAITNAANTRLRHAGGVAAAIARAGGPELQRESTE----K 255
Query 1095 GPLKVGGSC-VLSGHNLAKHCLH 1116
P+ +G + +G A++ +H
Sbjct 256 APIGLGEAVETTAGDMPARYVIH 278
>sp|P26627|R1AB_CVMJD Replicase polyprotein 1ab (Fragment) OS=Murine
coronavirus (strain defective JHM) OX=11143 GN=rep PE=3
SV=1
Length=500
Score = 37.7 bits (86), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 45/183 (25%), Positives = 74/183 (40%), Gaps = 15/183 (8%)
Query 1596 PTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLR-VEAFEYYHTTDPSFLGRYMSALNHTK 1654
P ++ D+ K++ E +T P D T V AF+ ++ S S H K
Sbjct 316 PDQVEAFDIEKVEDSILSELQTELNAPADKTYEDVLAFDAIYSETLSAFYAVPSDETHFK 375
Query 1655 KWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALI 1714
V G S NC+L + L+ +Q + L+F +Q + +AG F +
Sbjct 376 ------VCGFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKL 429
Query 1715 LAYCNKT-VGELGDVRETMSYLFQHANLDSC--KRVLNVVCKTCGQQQTTLKGVEAVMYM 1771
+ K+ + G +Y F L C K N C CG + L+G++AV +
Sbjct 430 VKSAPKSIILPQGGYVADFAYFF----LSQCSFKVHANWRCLKCG-MELKLQGLDAVFFY 484
Query 1772 GTL 1774
G +
Sbjct 485 GDV 487
>sp|E9QAM5|HELZ2_MOUSE 3'-5' exoribonuclease HELZ2 OS=Mus musculus
OX=10090 GN=Helz2 PE=1 SV=1
Length=2947
Score = 38.1 bits (87), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 30/95 (32%), Positives = 45/95 (47%), Gaps = 27/95 (28%)
Query 5836 ISPYNSQNAVASK------ILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVN------ 5883
++PYN+Q A S+ + G+ ++ SQGSE+ YVI + T T +V+
Sbjct 2819 LTPYNAQAAAISRGLMQRGVTGVTVTSITKSQGSEWRYVIVS-TVRTCPRSDVDQRPTKS 2877
Query 5884 -------------RFNVAITRAKVGILCIMSDRDL 5905
+ NVAITRA+ LCI+ D L
Sbjct 2878 WLKKFLGFVVDPHQVNVAITRAQEA-LCIIGDHLL 2911
>sp|Q6X2U4|POLN_RUBVB Non-structural polyprotein p200 OS=Rubella
virus (strain BRD1) OX=376262 PE=3 SV=1
Length=2116
Score = 38.1 bits (87), Expect = 4.4, Method: Composition-based stats.
Identities = 44/165 (27%), Positives = 69/165 (42%), Gaps = 22/165 (13%)
Query 1007 EVQPQLEME----LTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAAN 1062
+ +P++ E TP + + Y + V+++ +I++ K VVVNAAN
Sbjct 784 DAEPEVACEPGGPATPTRADPDSDIVESYARAAGPVHLRVRNIMDPPPGCK--VVVNAAN 841
Query 1063 VYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA-KHCLHVVGPN 1121
L G GV GA+ A+ A E +A P G + GH H +H V P
Sbjct 842 EGLLAGSGVCGAIF-ASAAATLAEDCRRLA---PCPTGEAVATPGHGCGYTHIIHAVAPR 897
Query 1122 VNKG-----EDIQLLKSAYENF------NQHEVLLAPLLSAGIFG 1155
+ + LL+ AY + + + PLL AGI+G
Sbjct 898 RPQDPAALEQSEALLERAYRSVVALAAARRWACVACPLLGAGIYG 942
>sp|Q8Y3S3|Y2759_LISMO Macro domain-containing protein lmo2759
OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679
/ EGD-e) OX=169963 GN=lmo2759 PE=4 SV=1
Length=176
Score = 36.6 bits (83), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 76/175 (43%), Gaps = 27/175 (15%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
+ I DI E+ + V+VNAAN L GGGV GA+++A + E + I G
Sbjct 3 ITIVKGDITEQ----EVDVIVNAANSGLLGGGGVDGAIHQAAGPDLLKECQEVINRIGSC 58
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLA--------PL 1148
G + + S +L A + +H VGP GE + K A + ++ P
Sbjct 59 PAGEAVITSAGDLKATYIIHAVGPIWKDGEHQEANKLASCYWKALDLAAGKDLTSIAFPN 118
Query 1149 LSAGIFGADPIHSLRVCVDTVR-----------TNVYLAVFDKN---LYDKLVSS 1189
+S G++G + V + TVR + FD+ LY+KL++S
Sbjct 119 ISTGVYGFPKKLAAEVALYTVRKWAEEEYDTSIKEIRFVCFDEENLKLYNKLINS 173
>sp|Q04561|RPOA_PRRSL Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain Lelystad) OX=11049
GN=rep PE=1 SV=3
Length=3855
Score = 38.1 bits (87), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 60/266 (23%), Positives = 99/266 (37%), Gaps = 72/266 (27%)
Query 4909 DSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQ------ 4962
D S + D + A + T+T LK +K + RT+ G + + +R
Sbjct 2696 DVQSIPEIDEMCARAVKENWQTVTPCTLKKQYCSKPKTRTILGTNNFIALAHRSALSGVT 2755
Query 4963 --FHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPN 5020
F +K KS + +G +KF K ++ V L D CDR+ P
Sbjct 2756 QAFMKKAWKS-------PIALGKNKF--------KELHCTVAGRCLEA-DLASCDRSTPA 2799
Query 5021 MLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVM-CGGSL-------YVKPGGT 5072
++R + +L Y LA C + L V+ C L + K GG
Sbjct 2800 IVRWFVANLL--------------YELAG-CEEYLPSYVLNCCHDLVATQDGAFTKRGGL 2844
Query 5073 SSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTD 5132
SSGD T+ +N+V+++ V QH + L ++
Sbjct 2845 SSGDPVTSVSNTVYSL-----------------------VIYAQHMVLSALKMGHEIGLK 2881
Query 5133 FVNEFYAY--LRKHFSMMILSDDAVV 5156
F+ E + L + M++ SDD V+
Sbjct 2882 FLEEQLKFEDLLEIQPMLVYSDDLVL 2907
>sp|A0A339|NDHK_COFAR NAD(P)H-quinone oxidoreductase subunit K,
chloroplastic OS=Coffea arabica OX=13443 GN=ndhK PE=3 SV=1
Length=229
Score = 37.0 bits (84), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 20/98 (20%), Positives = 49/98 (50%), Gaps = 14/98 (14%)
Query 5728 QLPAPRTLL-------TKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL- 5779
Q+P P+ ++ T G + +++V + K I D++L C P ++D ++ L
Sbjct 95 QMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLR 154
Query 5780 ------VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSA 5811
+Y+++++ + +S +CF +K I+ +++
Sbjct 155 KKISREIYEDRIRPQRQRSNRCFTTNHKFHISRSMNTG 192
>sp|Q89330|POLG_ZYMVR Genome polyprotein OS=Zucchini yellow mosaic
virus (strain Reunion Island) OX=117129 PE=3 SV=1
Length=3083
Score = 38.1 bits (87), Expect = 4.9, Method: Compositional matrix adjust.
Identities = 57/270 (21%), Positives = 109/270 (40%), Gaps = 48/270 (18%)
Query 4846 DYYRYNLPTMCDIRQLLFVVEVVDKY------FDCYDGGCINANQVIVNNLDKSAGFPFN 4899
D+++YN P + + +E VD F+ + I + I ++L+ A
Sbjct 2359 DFFKYNKPVIVNQLDHDKFLEAVDGVIRMMCDFEFNECRFITDPEEIYSSLNMKAAIGAQ 2418
Query 4900 KWGKARLYYDSM-SYEDQDALFAYTKR--NVIPTITQMNLKYAIS-----AKNRART--- 4948
GK + Y++ + +++ + LF +R N + +LK + N+ RT
Sbjct 2419 YRGKKKEYFEGLDNFDMERLLFQSCERLFNGYKGLWNGSLKAELRPLEKVQANKTRTFTA 2478
Query 4949 -----VAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVEN 5003
+ G +C N +F+ K LK +G SKFYGGW +++ +
Sbjct 2479 APIDTLLGAKVCVDDFNNEFYSKNLK-------CPWTVGMSKFYGGWDKLMRALPD---- 2527
Query 5004 PHLMGWDYPKCDRAM------PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSE 5057
GW Y D + P +L A L++ + + L N A+++
Sbjct 2528 ----GWLYCHADGSQFDSSLTPALLN--AVLIIRSFYMEDWWVGQEM--LENLYAEIVYT 2579
Query 5058 MVMC-GGSLYVKPGGTSSGDATTAYANSVF 5086
++ G+++ K G +SG +T N++
Sbjct 2580 PILAPDGTIFKKFRGNNSGQPSTVVDNTLM 2609
>sp|Q6X2U2|POLN_RUBVC Non-structural polyprotein p200 OS=Rubella
virus (strain BRDII) OX=376263 PE=3 SV=1
Length=2116
Score = 38.1 bits (87), Expect = 4.9, Method: Composition-based stats.
Identities = 44/165 (27%), Positives = 69/165 (42%), Gaps = 22/165 (13%)
Query 1007 EVQPQLEME----LTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAAN 1062
+ +P++ E TP + + Y + V+++ +I++ K VVVNAAN
Sbjct 784 DAEPEVACEPGGPATPARADPDSDIVESYARAAGPVHLRVRNIMDPPPGCK--VVVNAAN 841
Query 1063 VYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA-KHCLHVVGPN 1121
L G GV GA+ A+ A E +A P G + GH H +H V P
Sbjct 842 EGLLAGSGVCGAIF-ASAAASLAEDCRRLA---PCPTGEAVATPGHGCGYAHIIHAVAPR 897
Query 1122 VNKG-----EDIQLLKSAYENF------NQHEVLLAPLLSAGIFG 1155
+ + LL+ AY + + + PLL AGI+G
Sbjct 898 RPQDPAALEQSEALLERAYRSIVALAAARRWTCVACPLLGAGIYG 942
>sp|A0A0D2UG83|H2AY_CAPO3 Histone macroH2A1.1 OS=Capsaspora owczarzaki
(strain ATCC 30864) OX=595528 GN=CAOG_004778 PE=1 SV=1
Length=368
Score = 37.4 bits (85), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 29/91 (32%), Positives = 46/91 (51%), Gaps = 5/91 (5%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L L +Y+ N D+ E V+ VV+ N + G V GA+ A + E + Y+
Sbjct 191 LHLGQTLYVVNGDLTE----VRCDAVVHPTNGTMSFAGQVGGAIRAAAGAGVDAEVNSYM 246
Query 1092 ATNGPLKVGGSCVLSGHNL-AKHCLHVVGPN 1121
+ + L+V + + SGHNL +K +HV PN
Sbjct 247 SEHSQLQVTKAAITSGHNLPSKWIVHVHSPN 277
>sp|Q926Y8|Y2902_LISIN Macro domain-containing protein lin2902
OS=Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP
11262) OX=272626 GN=lin2902 PE=4 SV=1
Length=176
Score = 36.2 bits (82), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 45/157 (29%), Positives = 68/157 (43%), Gaps = 23/157 (15%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKH-C 1114
V+VNAAN L GGGV GA+++A + E + I G G + + S +L H
Sbjct 17 VIVNAANPGLLGGGGVDGAIHQAAGPDLLKECQEVINRIGSCPAGEAVITSAGDLKAHFI 76
Query 1115 LHVVGPNVNKGEDIQLLKSAYENFNQHEVLLA--------PLLSAGIFGADPIHSLRVCV 1166
+H VGP GE + K A + ++ P +S G++G + V +
Sbjct 77 IHAVGPIWKDGEHQEANKLASCYWKALDLAAGKDLTSIAFPNISTGVYGFPKKLAAEVAL 136
Query 1167 DTVR-----------TNVYLAVFDKN---LYDKLVSS 1189
TVR V FD+ LY+KL++S
Sbjct 137 YTVRKWAEEEYDSSIKEVRFVCFDEENLTLYNKLINS 173
>sp|A0MD28|RPOA_PRRSS Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (isolate Pig/United
States/SD 01-08/2001) OX=857306 PE=1 SV=2
Length=3838
Score = 37.7 bits (86), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 59/266 (22%), Positives = 99/266 (37%), Gaps = 72/266 (27%)
Query 4909 DSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQ------ 4962
D S + D + A + T+T LK +K + RT+ G + + +R
Sbjct 2679 DVQSIPEIDEMCARAVKENWQTVTPCTLKKQYCSKPKTRTILGTNNFIALAHRSALSGVT 2738
Query 4963 --FHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPN 5020
F +K KS + +G +KF K ++ V L D CDR+ P
Sbjct 2739 QAFMKKAWKS-------PIALGKNKF--------KELHCTVAGRCLEA-DLASCDRSTPA 2782
Query 5021 MLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVM-CGGSL-------YVKPGGT 5072
++R + +L Y LA C + L V+ C L + K GG
Sbjct 2783 IVRWFVANLL--------------YELAG-CEEYLPSYVLNCCHDLVATQDGAFTKRGGL 2827
Query 5073 SSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTD 5132
SSGD T+ +N+V+++ + QH + L ++
Sbjct 2828 SSGDPVTSVSNTVYSL-----------------------IIYAQHMVLSALKMGHEIGLK 2864
Query 5133 FVNEFYAY--LRKHFSMMILSDDAVV 5156
F+ E + L + M++ SDD V+
Sbjct 2865 FLEEQLKFEDLLEIQPMLVYSDDLVL 2890
>sp|Q3UYG8|MACD2_MOUSE ADP-ribose glycohydrolase MACROD2 OS=Mus
musculus OX=10090 GN=Macrod2 PE=1 SV=1
Length=475
Score = 37.4 bits (85), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 38/112 (34%), Positives = 55/112 (49%), Gaps = 18/112 (16%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHC 1114
+VNAAN L GGGV G +++A + E + NG + G + + G++L AK+
Sbjct 86 AIVNAANASLLGGGGVDGCIHRAAGPCLLAECRNL---NG-CETGHAKITCGYDLPAKYV 141
Query 1115 LHVVGP------NVNKGEDI-----QLLKSAYENFNQHEVLLAPLLSAGIFG 1155
+H VGP N + ED+ LK EN N V P +S GI+G
Sbjct 142 IHTVGPIARGHINGSHKEDLANCYQSSLKLVKEN-NLRSVAF-PCISTGIYG 191
>sp|B4S3G9|PDXJ_PROA2 Pyridoxine 5'-phosphate synthase OS=Prosthecochloris
aestuarii (strain DSM 271 / SK 413) OX=290512 GN=pdxJ
PE=3 SV=1
Length=236
Score = 36.6 bits (83), Expect = 6.1, Method: Composition-based stats.
Identities = 33/119 (28%), Positives = 49/119 (41%), Gaps = 16/119 (13%)
Query 2021 TSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDII-LKP 2079
T FD+++ D C +KPV + +E + E + +I+ L
Sbjct 100 TEGGFDIIRHYDT------LCRYIKPVQDAGIEVSIFIEPEEEAIERAASAGAEIVELHT 153
Query 2080 ANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTI 2138
SLK T T+LM I+K +R GL+ +A HGL N VP+ TI
Sbjct 154 GPYSLKKTPAELETELM---------RIRKAATFARSRGLRVVAGHGLDYFNIVPFRTI 203
>sp|Q71W03|Y2748_LISMF Macro domain-containing protein LMOf2365_2748
OS=Listeria monocytogenes serotype 4b (strain F2365)
OX=265669 GN=LMOf2365_2748 PE=4 SV=1
Length=176
Score = 35.8 bits (81), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 45/157 (29%), Positives = 69/157 (44%), Gaps = 23/157 (15%)
Query 1056 VVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHC 1114
V+VNAAN L GGGV GA+++A + E + I G G + + S +L A +
Sbjct 17 VIVNAANPGLLGGGGVDGAIHQAAGPDLLKECQEVINRIGTCPAGEAVITSAGDLQASYI 76
Query 1115 LHVVGPNVNKGE--DIQLLKSAYENF------NQHEVLLAPLLSAGIFGADPIHSLRVCV 1166
+H VGP GE + L S Y + + P +S G++G + V +
Sbjct 77 IHAVGPIWKDGEHQEANKLASCYWKALDLAAGKELTSIAFPNISTGVYGFPKKLAAEVAL 136
Query 1167 DTVRT-----------NVYLAVFDKN---LYDKLVSS 1189
TVR + FD+ LY+KL++S
Sbjct 137 YTVRKWAEEEYDTSIEEIRFVCFDEENLKLYNKLINS 173
>sp|A1Z1Q3|MACD2_HUMAN ADP-ribose glycohydrolase MACROD2 OS=Homo
sapiens OX=9606 GN=MACROD2 PE=1 SV=2
Length=425
Score = 37.0 bits (84), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 39/132 (30%), Positives = 65/132 (49%), Gaps = 18/132 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
LT+ V + DI ++ +VNAAN L GGGV G +++A + E +
Sbjct 68 LTEKVSLYRGDIT----LLEVDAIVNAANASLLGGGGVDGCIHRAAGPCLLAECRNL--- 120
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGP------NVNKGEDI-QLLKSAYENFNQHEV-- 1143
NG G + + G++L AK+ +H VGP N + ED+ KS+ + ++ +
Sbjct 121 NG-CDTGHAKITCGYDLPAKYVIHTVGPIARGHINGSHKEDLANCYKSSLKLVKENNIRS 179
Query 1144 LLAPLLSAGIFG 1155
+ P +S GI+G
Sbjct 180 VAFPCISTGIYG 191
>sp|Q83017|RPOA_LDVP Replicase polyprotein 1ab OS=Lactate dehydrogenase
elevating virus (strain Plagemann) OX=300016 GN=rep
PE=1 SV=2
Length=3616
Score = 37.4 bits (85), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 44/183 (24%), Positives = 73/183 (40%), Gaps = 27/183 (15%)
Query 4912 SYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKS- 4970
S+ D DAL T+T LK +K++ RT+ G + + R + +
Sbjct 2506 SHPDIDALCKRACEEHWQTVTPCTLKKQYCSKSKTRTILGTNNFVALGLRSALSGVTQGF 2565
Query 4971 IAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLR-----IM 5025
+ G + +G +KF T + D CDR+ P ++R ++
Sbjct 2566 MRKGIGTPICLGKNKF---------TPLPVRIGGRCLEADLASCDRSTPAIIRWFTTNLL 2616
Query 5026 ASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSV 5085
L A + L N C V+S M C + K GG SSGD T+ +N+V
Sbjct 2617 FELAGAEEWIPSYVL--------NCCHDVVSTMSGC----FDKRGGLSSGDPVTSISNTV 2664
Query 5086 FNI 5088
+++
Sbjct 2665 YSL 2667
>sp|Q9J6K9|POLN_RUBVD Non-structural polyprotein p200 OS=Rubella
virus (strain Cendehill) OX=376266 PE=3 SV=2
Length=2116
Score = 37.4 bits (85), Expect = 8.0, Method: Composition-based stats.
Identities = 39/139 (28%), Positives = 58/139 (42%), Gaps = 22/139 (16%)
Query 1031 YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDY 1090
Y + V+++ DI++ K VVVNAAN L G GV GA+ A+ +
Sbjct 812 YARAAGPVHLRVRDIMDPPPGCK--VVVNAANEGLLAGSGVCGAIFANATAALAADCRRL 869
Query 1091 IATNGPLKVGGSCVLSGHNLA-KHCLHVVGPN-------VNKGEDIQLLKSAYENF---- 1138
P G + GH H +H V P + +GE LL+ AY +
Sbjct 870 ----APCPTGEAVATPGHGCGYTHIIHAVAPRRPRDPAALEEGE--ALLERAYRSIVALA 923
Query 1139 --NQHEVLLAPLLSAGIFG 1155
+ + PLL AG++G
Sbjct 924 AARRWAYVACPLLGAGVYG 942
>sp|Q86500|POLN_RUBVM Non-structural polyprotein p200 OS=Rubella
virus (strain M33) OX=11043 PE=1 SV=2
Length=2116
Score = 37.0 bits (84), Expect = 9.1, Method: Composition-based stats.
Identities = 39/139 (28%), Positives = 57/139 (41%), Gaps = 22/139 (16%)
Query 1031 YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDY 1090
Y + V+++ DI++ K VVVNAAN L G GV GA+ A+ +
Sbjct 812 YARAAGPVHLRVRDIMDPPPGCK--VVVNAANEGLLAGSGVCGAIFANATAALAADCRRL 869
Query 1091 IATNGPLKVGGSCVLSGHNLA-KHCLHVVGPN-------VNKGEDIQLLKSAYENFNQHE 1142
P +G + GH H +H V P + +GE LL+ AY +
Sbjct 870 ----APCPIGEAVATPGHGCGYTHIIHAVAPRRPRDPAALEEGE--ALLERAYRSIVALA 923
Query 1143 VLLA------PLLSAGIFG 1155
PLL AG++G
Sbjct 924 AARRWARVACPLLGAGVYG 942
>sp|Q3ZX83|TIG_DEHMC Trigger factor OS=Dehalococcoides mccartyi
(strain CBDB1) OX=255470 GN=tig PE=3 SV=1
Length=447
Score = 36.6 bits (83), Expect = 9.7, Method: Composition-based stats.
Identities = 27/115 (23%), Positives = 57/115 (50%), Gaps = 9/115 (8%)
Query 3926 DINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAY----EQAVANGDSEVVLKKLK 3981
+++++ E+ L + EF ++ S Q+ Y EQ VA S +VL KL
Sbjct 308 ELDQIIEQQLQRLQSNVKSPEEFRAMLSQMTPEDMQQRYRPLAEQRVA---SSLVLGKLA 364
Query 3982 KSLNVAKSEFDRDAAMQRKLEKMADQAMTQ--MYKQARSEDKRAKVTSAMQTMLF 4034
+ N+ ++ + DA +++ + D+ + +Y Q+ + D+ ++ +A +TM F
Sbjct 365 TTENLVPNDEEVDAEIEKLITDAGDKKEEEKALYNQSETRDRLIQLLTARKTMAF 419
>sp|Q5ZKG3|DNA2_CHICK DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Gallus gallus OX=9031 GN=DNA2 PE=2 SV=2
Length=992
Score = 37.0 bits (84), Expect = 9.9, Method: Compositional matrix adjust.
Identities = 78/371 (21%), Positives = 136/371 (37%), Gaps = 93/371 (25%)
Query 5601 YSTLQGPPGTGKSHFAIGLALYYPSA--RIVYTACSHAAVDALCEKALKY----LPIDKC 5654
Y+ + G PGTGK+ L + ++ T+ +H AVD + K K+ L + +
Sbjct 612 YTLIVGMPGTGKTTTICALVRILSACGFSVLLTSFTHTAVDNILLKLAKFKVGFLRLGRA 671
Query 5655 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPE--------TTADIVVFDEISMATNY 5706
++ P KF +V L E TA + + I + +
Sbjct 672 QKVHPD------IRKFTEEEICRSKSIKSVTDLEELYNSQPVVATACMGINHPIFVQKQF 725
Query 5707 DLSVVNARLR------------AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC---R 5751
D +V+ + +K +V +GD QLP L + + + S R
Sbjct 726 DFCIVDEASQISQPICLGPLFCSKRFVLVGDHQQLPP----LVQNSEARDLGMSESLFKR 781
Query 5752 LMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSA 5811
L + + L R ++I+ + LVY+ KL+ +K + ++
Sbjct 782 LEQNQNAVVQLTVQYRMNSKIMSLSNKLVYEGKLECGSEKVS---------------NAT 826
Query 5812 INRPQIGVVR-EFLTRNPAWRKAVF-----------------------ISPYNSQNAVAS 5847
N P + +++ EF + W K V ISPY Q V +
Sbjct 827 ANLPNLKMLKLEFADASKTWLKEVLEPDKPVCFLNTEKAGCRPSDIGIISPYRHQLKVIT 886
Query 5848 KILG------LPTQTVDSSQGSEYDYVIFTQTTET------AHSCNVNRFNVAITRAK-- 5893
++ + T+D QG + +I + + A + R NVAITRAK
Sbjct 887 DLMARLKENRVEVNTIDKYQGRDKSIIIVSFVRNSNDENLGALLKDWRRLNVAITRAKHK 946
Query 5894 -VGILCIMSDR 5903
+ + C+ S R
Sbjct 947 LIMVGCVPSLR 957
>sp|B0C385|RPOC2_ACAM1 DNA-directed RNA polymerase subunit beta'
OS=Acaryochloris marina (strain MBIC 11017) OX=329726 GN=rpoC2
PE=3 SV=1
Length=1330
Score = 37.0 bits (84), Expect = 9.9, Method: Compositional matrix adjust.
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 12/82 (15%)
Query 1045 IVEEAKKVKPTVVVNAANVYLKHGGGVAG--ALNKATNNAMQVESDDYI----------A 1092
+VEE +++ P VV + K GG V G + N+AT + + DD I A
Sbjct 860 LVEEGQQIDPGAVVARTEIKAKQGGKVRGIRSGNEATRRILLMTDDDLITIETQGKATSA 919
Query 1093 TNGPLKVGGSCVLSGHNLAKHC 1114
+ G L G V +G +A+ C
Sbjct 920 SEGELLRAGDEVAAGVTVAESC 941
Lambda K H a alpha
0.321 0.135 0.412 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 873118871808
Results from round 2
Query= sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1 SV=1
Length=7096
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res... 10399 0.0
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re... 10373 0.0
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus... 10328 0.0
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus... 10325 0.0
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus... 10322 0.0
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus... 8972 0.0
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus... 8670 0.0
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res... 8149 0.0
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus... 8038 0.0
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus... 8033 0.0
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir... 7970 0.0
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi... 7960 0.0
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi... 7919 0.0
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi... 7798 0.0
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi... 7797 0.0
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir... 7745 0.0
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir... 7737 0.0
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir... 7730 0.0
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir... 7722 0.0
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir... 7714 0.0
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir... 7602 0.0
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus... 6841 0.0
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi... 6838 0.0
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi... 6782 0.0
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir... 6772 0.0
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir... 6758 0.0
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir... 6723 0.0
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious... 6690 0.0
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou... 6688 0.0
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious... 6673 0.0
sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute resp... 5954 0.0
sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respi... 5939 0.0
sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus H... 5892 0.0
sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus R... 5891 0.0
sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus 2... 5886 0.0
sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus H... 4633 0.0
sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus H... 4467 0.0
sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respi... 3835 0.0
sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus H... 3715 0.0
sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus 1... 3714 0.0
sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus... 3643 0.0
sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronaviru... 3640 0.0
sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronaviru... 3635 0.0
sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronaviru... 3533 0.0
sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronaviru... 3531 0.0
sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus... 3506 0.0
sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus... 3503 0.0
sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus... 3493 0.0
sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus... 3492 0.0
sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus... 3491 0.0
sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus... 3485 0.0
sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious ... 2677 0.0
sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious b... 2677 0.0
sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious b... 2655 0.0
sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus... 2602 0.0
sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus 5... 2595 0.0
sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic ... 2584 0.0
sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus... 2572 0.0
sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmiss... 2548 0.0
sp|P18457|R1AB_CVPFS Replicase polyprotein 1ab (Fragment) OS=Porc... 757 0.0
sp|P12723|R1AB_IBVK Replicase polyprotein 1ab (Fragment) OS=Avian... 647 0.0
sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11... 612 2e-173
sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus 1 OX... 605 2e-171
sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream vir... 588 4e-166
sp|Q9WQ77|R1AB_CVRSD Replicase polyprotein 1ab (Fragment) OS=Rat ... 518 1e-165
sp|Q9WQ76|R1AB_CVTMI Replicase polyprotein 1ab (Fragment) OS=Turk... 489 7e-156
sp|P36697|R1AB_CVCAI Replicase polyprotein 1ab (Fragment) OS=Cani... 266 4e-80
sp|Q04158|R1AB_CVPR8 Replicase polyprotein 1ab (Fragment) OS=Porc... 211 2e-61
sp|A7MG20|YMDB_CROS8 O-acetyl-ADP-ribose deacetylase OS=Cronobact... 190 1e-53
sp|C9Y0V8|YMDB_CROTZ O-acetyl-ADP-ribose deacetylase OS=Cronobact... 189 5e-53
sp|B7LT90|YMDB_ESCF3 O-acetyl-ADP-ribose deacetylase OS=Escherich... 184 1e-51
sp|D2TT52|YMDB_CITRI O-acetyl-ADP-ribose deacetylase OS=Citrobact... 184 1e-51
sp|B4T2X8|YMDB_SALNS O-acetyl-ADP-ribose deacetylase OS=Salmonell... 184 2e-51
sp|B5F961|YMDB_SALA4 O-acetyl-ADP-ribose deacetylase OS=Salmonell... 184 3e-51
sp|P67341|YMDB_SALTY O-acetyl-ADP-ribose deacetylase OS=Salmonell... 184 3e-51
sp|P67342|YMDB_SALTI O-acetyl-ADP-ribose deacetylase OS=Salmonell... 184 3e-51
sp|B5RBF3|YMDB_SALG2 O-acetyl-ADP-ribose deacetylase OS=Salmonell... 182 1e-50
sp|A8AI35|YMDB_CITK8 O-acetyl-ADP-ribose deacetylase OS=Citrobact... 182 2e-50
sp|P0A8D6|YMDB_ECOLI O-acetyl-ADP-ribose deacetylase OS=Escherich... 181 3e-50
sp|P0A8D7|YMDB_ECOL6 O-acetyl-ADP-ribose deacetylase OS=Escherich... 181 3e-50
sp|P0A8D8|YMDB_ECO57 O-acetyl-ADP-ribose deacetylase OS=Escherich... 181 3e-50
sp|Q0T5Z6|YMDB_SHIF8 O-acetyl-ADP-ribose deacetylase OS=Shigella ... 179 9e-50
sp|A4W960|YMDB_ENT38 O-acetyl-ADP-ribose deacetylase OS=Enterobac... 176 1e-48
sp|D5CE05|YMDB_ENTCC O-acetyl-ADP-ribose deacetylase OS=Enterobac... 176 2e-48
sp|Q32E73|YMDB_SHIDS O-acetyl-ADP-ribose deacetylase OS=Shigella ... 175 3e-48
sp|P38859|DNA2_YEAST DNA replication ATP-dependent helicase/nucle... 196 4e-48
sp|D3RKJ0|YMDB_KLEVT O-acetyl-ADP-ribose deacetylase OS=Klebsiell... 174 5e-48
sp|B5XXK9|YMDB_KLEP3 O-acetyl-ADP-ribose deacetylase OS=Klebsiell... 174 5e-48
sp|B6SFA4|MAA3_ARATH Probable helicase MAGATAMA 3 OS=Arabidopsis ... 189 3e-47
sp|E1SDF1|YMDB1_PANVC O-acetyl-ADP-ribose deacetylase 1 OS=Pantoe... 172 4e-47
sp|Q8EYT0|Y4133_LEPIN Macro domain-containing protein LA_4133 OS=... 167 2e-45
sp|Q72M93|Y3295_LEPIC Macro domain-containing protein LIC_13295 O... 167 2e-45
sp|Q96XY5|Y2383_SULTO Uncharacterized protein STK_23830 OS=Sulfur... 164 3e-44
sp|Q97UU4|Y2899_SACS2 Uncharacterized protein SSO2899 OS=Saccharo... 161 3e-43
sp|Q8ZXT3|Y1111_PYRAE Uncharacterized protein PAE1111 OS=Pyrobacu... 159 2e-42
sp|Q8RB30|Y995_CALS4 Macro domain-containing protein TTE0995 OS=C... 158 3e-42
sp|E1PL40|YMDB2_PANVC O-acetyl-ADP-ribose deacetylase 2 OS=Pantoe... 156 9e-42
sp|Q8TQD0|Y1614_METAC Macro domain-containing protein MA_1614 OS=... 154 1e-40
sp|Q4J9D2|Y1252_SULAC Uncharacterized protein Saci_1252 OS=Sulfol... 153 1e-40
sp|Q8Q0F9|Y177_METMA Macro domain-containing protein MM_0177 OS=M... 153 1e-40
sp|Q92355|SEN1_SCHPO Helicase sen1 OS=Schizosaccharomyces pombe (... 171 2e-40
sp|Q9WYX8|Y508_THEMA Uncharacterized protein TM_0508 OS=Thermotog... 155 6e-37
sp|Q87JZ5|Y4103_VIBPA Macro domain-containing protein VPA0103 OS=... 141 2e-36
sp|Q8RHQ2|Y1951_FUSNN Uncharacterized protein FN1951 OS=Fusobacte... 134 6e-34
sp|Q2EMV9|PAR14_MOUSE Protein mono-ADP-ribosyltransferase PARP14 ... 138 1e-30
sp|Q8CAS9|PARP9_MOUSE Protein mono-ADP-ribosyltransferase PARP9 O... 137 2e-30
sp|Q460N5|PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14 ... 137 3e-30
sp|P0C6F3|R1A_BEV Replicase polyprotein 1a OS=Berne virus OX=1115... 137 3e-30
sp|Q8IXQ6|PARP9_HUMAN Protein mono-ADP-ribosyltransferase PARP9 O... 136 3e-30
sp|P0C6F4|R1A_BRV1 Replicase polyprotein 1a OS=Breda virus 1 OX=3... 127 6e-27
sp|P36328|POLN_EEVVP Polyprotein P1234 OS=Venezuelan equine encep... 124 3e-26
sp|P36327|POLN_EEVV3 Polyprotein P1234 OS=Venezuelan equine encep... 124 3e-26
sp|P27282|POLN_EEVVT Polyprotein P1234 OS=Venezuelan equine encep... 124 3e-26
sp|Q9WJC7|POLN_EEVVM Polyprotein P1234 OS=Venezuelan equine encep... 122 2e-25
sp|Q8V294|POLN_EEVVC Polyprotein P1234 OS=Venezuelan equine encep... 122 2e-25
Sequences not found previously or not previously below threshold:
sp|Q8KAE4|Y2219_CHLTE Macro domain-containing protein CT2219 OS=C... 147 1e-38
sp|Q8Y3S3|Y2759_LISMO Macro domain-containing protein lmo2759 OS=... 142 1e-36
sp|Q71W03|Y2748_LISMF Macro domain-containing protein LMOf2365_27... 141 2e-36
sp|Q926Y8|Y2902_LISIN Macro domain-containing protein lin2902 OS=... 141 2e-36
sp|Q7MTZ7|MACRO_PORGI Macro domain-containing protein PG1779 OS=P... 140 4e-36
sp|Q9HXU7|Y3693_PSEAE Macro domain-containing protein PA3693 OS=P... 137 4e-35
sp|Q9ZBG3|Y6450_STRCO Macro domain-containing protein SCO6450 OS=... 136 1e-34
sp|Q93SX7|Y189_ACISE Macro domain-containing protein OS=Acinetoba... 136 1e-34
sp|Q8Y2K1|Y334_RALN1 Macro domain-containing protein RSc0334 OS=R... 136 1e-34
sp|Q9KHE2|Y189_STRGR Macro domain-containing protein in non 5'reg... 136 1e-34
sp|Q8P5Z8|Y3184_XANCP Macro domain-containing protein XCC3184 OS=... 135 2e-34
sp|Q8PHB6|Y3343_XANAC Macro domain-containing protein XAC3343 OS=... 135 3e-34
sp|Q44020|YGB2_CUPNE Macro domain-containing protein in gbd 3'reg... 134 4e-34
sp|Q88SK6|Y3408_LACPL Macro domain-containing protein lp_3408 OS=... 134 6e-34
sp|Q6PAV8|MACD2_XENLA ADP-ribose glycohydrolase MACROD2 OS=Xenopu... 140 1e-33
sp|Q9EYI6|Y189_STRNO Macro domain-containing protein in sno 5'reg... 132 2e-33
sp|Q97AU0|Y719_THEVO Uncharacterized protein TV0719 OS=Thermoplas... 132 3e-33
sp|Q985D2|Y7730_RHILO Macro domain-containing protein mll7730 OS=... 130 1e-32
sp|Q3UYG8|MACD2_MOUSE ADP-ribose glycohydrolase MACROD2 OS=Mus mu... 138 4e-32
sp|Q8K4G6|MACD1_RAT ADP-ribose glycohydrolase MACROD1 (Fragment) ... 131 6e-32
sp|A1Z1Q3|MACD2_HUMAN ADP-ribose glycohydrolase MACROD2 OS=Homo s... 135 1e-31
sp|Q9BQ69|MACD1_HUMAN ADP-ribose glycohydrolase MACROD1 OS=Homo s... 132 2e-31
sp|Q922B1|MACD1_MOUSE ADP-ribose glycohydrolase MACROD1 OS=Mus mu... 131 3e-31
sp|Q2KHU5|MACD1_BOVIN ADP-ribose glycohydrolase MACROD1 OS=Bos ta... 130 6e-31
sp|Q9RS39|Y2288_DEIRA Macro domain-containing protein DR_2288 OS=... 125 6e-31
sp|O94387|YGSA_SCHPO Uncharacterized ATP-dependent helicase C29A1... 138 2e-30
sp|Q9HJ67|Y1105_THEAC Uncharacterized protein Ta1105 OS=Thermopla... 123 1e-29
sp|Q5ZKG3|DNA2_CHICK DNA replication ATP-dependent helicase/nucle... 134 1e-29
sp|Q00416|SEN1_YEAST Helicase SEN1 OS=Saccharomyces cerevisiae (s... 132 1e-28
sp|Q86AS0|Y4399_DICDI Probable helicase DDB_G0274399 OS=Dictyoste... 130 4e-28
sp|E1BMP7|DNA2_BOVIN DNA replication ATP-dependent helicase/nucle... 128 2e-27
sp|P51530|DNA2_HUMAN DNA replication ATP-dependent helicase/nucle... 123 3e-26
sp|Q9HEH1|RENT1_NEUCR Regulator of nonsense transcripts 1 homolog... 123 4e-26
sp|D3ZG52|DNA2_RAT DNA replication ATP-dependent helicase/nucleas... 123 5e-26
sp|Q9V0Y3|Y656_PYRAB Uncharacterized protein PYRAB06560 OS=Pyroco... 111 7e-26
sp|Q9VYS3|RENT1_DROME Regulator of nonsense transcripts 1 homolog... 122 1e-25
sp|Q6ZQJ5|DNA2_MOUSE DNA replication ATP-dependent helicase/nucle... 121 2e-25
sp|O59182|Y1513_PYRHO Uncharacterized protein PH1513 OS=Pyrococcu... 110 2e-25
sp|Q09820|RENT1_SCHPO ATP-dependent helicase upf1 OS=Schizosaccha... 120 4e-25
sp|A2AKX3|SETX_MOUSE Probable helicase senataxin OS=Mus musculus ... 120 8e-25
sp|P26627|R1AB_CVMJD Replicase polyprotein 1ab (Fragment) OS=Muri... 115 1e-24
sp|Q9FJR0|RENT1_ARATH Regulator of nonsense transcripts 1 homolog... 118 1e-24
sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens ... 118 2e-24
sp|A0A1P8ASY1|JHS1_ARATH DNA replication ATP-dependent helicase/n... 118 2e-24
sp|Q8QHA5|DNA2_XENLA DNA replication ATP-dependent helicase/nucle... 117 3e-24
sp|P38935|SMBP2_HUMAN DNA-binding protein SMUBP-2 OS=Homo sapiens... 115 1e-23
sp|P30771|RENT1_YEAST ATP-dependent helicase NAM7 OS=Saccharomyce... 115 1e-23
sp|O28751|Y1521_ARCFU ADP-ribose glycohydrolase AF_1521 OS=Archae... 103 6e-23
sp|O76512|RENT1_CAEEL Regulator of nonsense transcripts 1 OS=Caen... 113 6e-23
sp|F1RCY6|RENT1_DANRE Regulator of nonsense transcripts 1 OS=Dani... 113 6e-23
sp|Q9EPU0|RENT1_MOUSE Regulator of nonsense transcripts 1 OS=Mus ... 112 8e-23
sp|Q92900|RENT1_HUMAN Regulator of nonsense transcripts 1 OS=Homo... 112 8e-23
sp|Q54I89|RENT1_DICDI Regulator of nonsense transcripts 1 OS=Dict... 112 1e-22
sp|Q57568|Y104_METJA Uncharacterized ATP-dependent helicase MJ010... 111 1e-22
sp|Q0VGT4|ZGRF1_MOUSE 5'-3' DNA helicase ZGRF1 OS=Mus musculus OX... 109 1e-21
sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 OS=Arabidopsis th... 107 3e-21
sp|Q8U0P9|Y1536_PYRFU Uncharacterized protein PF1536 OS=Pyrococcu... 96.7 1e-20
sp|O94247|HCS1_SCHPO DNA polymerase alpha-associated DNA helicase... 104 1e-20
sp|Q86YA3|ZGRF1_HUMAN 5'-3' DNA helicase ZGRF1 OS=Homo sapiens OX... 105 2e-20
sp|Q5JER1|Y1890_THEKO Uncharacterized protein TK1890 OS=Thermococ... 95.5 3e-20
sp|P34243|HCS1_YEAST DNA polymerase alpha-associated DNA helicase... 101 1e-19
sp|P0DC29|ADPRH_STRPQ Protein-ADP-ribose hydrolase OS=Streptococc... 95.1 3e-19
sp|P0DC28|ADPRH_STRP3 Protein-ADP-ribose hydrolase OS=Streptococc... 95.1 3e-19
sp|Q99ZI6|ADPRH_STRP1 Protein-ADP-ribose hydrolase OS=Streptococc... 95.1 3e-19
sp|Q4QXJ8|POLN_EEEVF Polyprotein P1234 OS=Eastern equine encephal... 101 4e-19
sp|Q1LXK5|M10B2_DANRE Putative helicase mov-10-B.2 OS=Danio rerio... 100 4e-19
sp|Q8P0X2|ADPRH_STRP8 Protein-ADP-ribose hydrolase OS=Streptococc... 94.8 4e-19
sp|Q5XC09|ADPRH_STRP6 Protein-ADP-ribose hydrolase OS=Streptococc... 94.4 5e-19
sp|Q008X5|R1A_WBV24 Replicase polyprotein 1a OS=White bream virus... 100 5e-19
sp|P0DN70|ADPRH_STRPG Protein-ADP-ribose hydrolase OS=Streptococc... 94.0 6e-19
sp|Q60560|SMBP2_MESAU DNA-binding protein SMUBP-2 OS=Mesocricetus... 99.0 1e-18
sp|Q8NYB7|ADPRH_STAAW Protein-ADP-ribose hydrolase OS=Staphylococ... 92.8 2e-18
sp|Q6GCE6|ADPRH_STAAS Protein-ADP-ribose hydrolase OS=Staphylococ... 92.8 2e-18
sp|Q5HIW9|ADPRH_STAAC Protein-ADP-ribose hydrolase OS=Staphylococ... 92.8 2e-18
sp|Q9URU2|DNA2_SCHPO DNA replication ATP-dependent helicase/nucle... 97.4 4e-18
sp|A7T167|GDAP2_NEMVE Protein GDAP2 homolog OS=Nematostella vecte... 95.5 4e-18
sp|Q6GJZ1|ADPRH_STAAR Protein-ADP-ribose hydrolase OS=Staphylococ... 91.7 4e-18
sp|P67344|ADPRH_STAAN Protein-ADP-ribose hydrolase OS=Staphylococ... 90.9 8e-18
sp|P67343|ADPRH_STAAM Protein-ADP-ribose hydrolase OS=Staphylococ... 90.9 8e-18
sp|Q1LXK4|M10B1_DANRE Putative helicase mov-10-B.1 OS=Danio rerio... 95.9 1e-17
sp|O67112|Y987_AQUAE Uncharacterized protein aq_987 OS=Aquifex ae... 87.4 1e-17
sp|P32644|ECM32_YEAST Putative ATP-dependent RNA helicase ECM32 O... 95.9 1e-17
sp|P23249|MOV10_MOUSE Putative helicase MOV-10 OS=Mus musculus OX... 95.5 1e-17
sp|P13896|POLN_WEEV Polyprotein P1234 OS=Western equine encephali... 95.9 2e-17
sp|Q9EQN5|SMBP2_RAT DNA-binding protein SMUBP-2 OS=Rattus norvegi... 95.1 2e-17
sp|Q306W6|POLN_EEEV1 Polyprotein P1234 OS=Eastern equine encephal... 95.5 2e-17
sp|Q7TZB9|Y1934_MYCBO Uncharacterized protein Mb1934c OS=Mycobact... 91.3 3e-17
sp|P9WK29|Y1899_MYCTU Uncharacterized protein Rv1899c OS=Mycobact... 91.3 3e-17
sp|Q5ZKD7|MOV10_CHICK Putative helicase MOV-10 OS=Gallus gallus O... 94.8 3e-17
sp|P9WK28|Y1899_MYCTO Uncharacterized protein MT1950 OS=Mycobacte... 91.3 3e-17
sp|Q8BCR0|POLN_RUBVN Non-structural polyprotein p200 OS=Rubella v... 94.8 3e-17
sp|P13889|POLN_RUBVT Non-structural polyprotein p200 OS=Rubella v... 93.6 7e-17
sp|Q98TR3|RENT1_TAKRU Putative regulator of nonsense transcripts ... 93.2 8e-17
sp|Q93RG0|ADPRH_TREMD Protein-ADP-ribose hydrolase OS=Treponema m... 87.8 9e-17
sp|Q306W8|POLN_EEEV8 Polyprotein P1234 OS=Eastern equine encephal... 92.8 1e-16
sp|Q6X2U2|POLN_RUBVC Non-structural polyprotein p200 OS=Rubella v... 92.8 1e-16
sp|P27283|POLN_SINDO Polyprotein P1234 OS=Sindbis virus subtype O... 92.8 1e-16
sp|Q9HCE1|MOV10_HUMAN Helicase MOV-10 OS=Homo sapiens OX=9606 GN=... 92.4 1e-16
sp|P03317|POLN_SINDV Polyprotein P1234 OS=Sindbis virus OX=11034 ... 92.4 2e-16
sp|P40694|SMBP2_MOUSE DNA-binding protein SMUBP-2 OS=Mus musculus... 91.3 3e-16
sp|Q86924|POLN_AURAV Polyprotein P1234 OS=Aura virus OX=44158 PE=... 91.7 3e-16
sp|Q6X2U4|POLN_RUBVB Non-structural polyprotein p200 OS=Rubella v... 91.3 4e-16
sp|Q99IE5|POLN_RUBVV Non-structural polyprotein p200 OS=Rubella v... 90.5 6e-16
sp|Q99IE7|POLN_RUBVO Non-structural polyprotein p200 OS=Rubella v... 90.5 6e-16
sp|Q8JUX6|POLN_CHIKS Polyprotein P1234 OS=Chikungunya virus (stra... 90.1 8e-16
sp|Q0V8H6|MOV10_BOVIN Putative helicase MOV-10 OS=Bos taurus OX=9... 89.7 8e-16
sp|Q5XXP4|POLN_CHIK3 Polyprotein P1234 OS=Chikungunya virus (stra... 89.7 1e-15
sp|Q09449|YQ12_CAEEL Uncharacterized ATP-dependent helicase C05C1... 89.7 1e-15
sp|O40955|POLN_RUBVR Non-structural polyprotein p200 OS=Rubella v... 89.4 1e-15
sp|Q9BXT6|M10L1_HUMAN RNA helicase Mov10l1 OS=Homo sapiens OX=960... 89.0 1e-15
sp|O93327|H2AY_CHICK Core histone macro-H2A.1 OS=Gallus gallus OX... 86.3 2e-15
sp|O75367|H2AY_HUMAN Core histone macro-H2A.1 OS=Homo sapiens OX=... 85.9 2e-15
sp|Q02874|H2AY_RAT Core histone macro-H2A.1 OS=Rattus norvegicus ... 85.9 2e-15
sp|Q9QZQ8|H2AY_MOUSE Core histone macro-H2A.1 OS=Mus musculus OX=... 85.1 4e-15
sp|O90370|POLN_ONNVI Polyprotein P1234 OS=O'nyong-nyong virus (st... 87.8 4e-15
sp|O90368|POLN_ONNVS Polyprotein P1234 OS=O'nyong-nyong virus (st... 87.0 7e-15
sp|P13886|POLN_ONNVG Polyprotein P1234 OS=O'nyong-nyong virus (st... 87.0 8e-15
sp|Q9J6K9|POLN_RUBVD Non-structural polyprotein p200 OS=Rubella v... 86.3 1e-14
sp|Q5XGM5|GDAP2_XENLA Ganglioside-induced differentiation-associa... 84.0 2e-14
sp|Q8QZ73|POLN_MAYAB Polyprotein P1234 OS=Mayaro virus (strain Br... 85.1 2e-14
sp|Q2KIX2|GDAP2_BOVIN Ganglioside-induced differentiation-associa... 83.6 3e-14
sp|E9QAM5|HELZ2_MOUSE 3'-5' exoribonuclease HELZ2 OS=Mus musculus... 84.7 3e-14
sp|Q5CZL1|GDAP2_XENTR Ganglioside-induced differentiation-associa... 82.4 6e-14
sp|P87515|POLN_BFV Polyprotein P1234 OS=Barmah forest virus OX=11... 84.0 6e-14
sp|Q9YBE9|Y1648_AERPE Uncharacterized protein APE_1648.1 OS=Aerop... 77.4 7e-14
sp|Q9DBL2|GDAP2_MOUSE Ganglioside-induced differentiation-associa... 82.0 8e-14
sp|Q9P2E3|ZNFX1_HUMAN NFX1-type zinc finger-containing protein 1 ... 83.2 1e-13
sp|P13887|POLN_RRVN Polyprotein P1234 OS=Ross river virus (strain... 82.8 2e-13
sp|P13888|POLN_RRVT Polyprotein nsP1234 (Fragment) OS=Ross river ... 82.4 2e-13
sp|Q8R151|ZNFX1_MOUSE NFX1-type zinc finger-containing protein 1 ... 82.0 2e-13
sp|Q86500|POLN_RUBVM Non-structural polyprotein p200 OS=Rubella v... 82.0 2e-13
sp|Q6QLN1|POLN_AHEV Non-structural polyprotein pORF1 OS=Avian hep... 81.7 3e-13
sp|Q9NXN4|GDAP2_HUMAN Ganglioside-induced differentiation-associa... 80.1 3e-13
sp|Q66H63|GDAP2_RAT Ganglioside-induced differentiation-associate... 80.1 3e-13
sp|Q8QL53|POLN_SLDV Polyprotein P1234 OS=Sleeping disease virus O... 81.3 5e-13
sp|Q99MV5|M10L1_MOUSE RNA helicase Mov10l1 OS=Mus musculus OX=100... 80.9 5e-13
sp|Q8JJX1|POLN_SPDV Polyprotein P1234 OS=Salmon pancreas disease ... 80.5 6e-13
sp|Q66HX8|GDAP2_DANRE Ganglioside-induced differentiation-associa... 79.0 8e-13
sp|E9P860|ZNFX1_CAEEL NFX1-type zinc finger-containing protein 1 ... 80.5 8e-13
sp|Q5Y389|POLN_GETV Polyprotein P1234 OS=Getah virus OX=59300 PE=... 80.1 1e-12
sp|Q9JGL0|POLN_SAGV Polyprotein P1234 OS=Sagiyama virus OX=59303 ... 79.7 1e-12
sp|Q9BYK8|HELZ2_HUMAN 3'-5' exoribonuclease HELZ2 OS=Homo sapiens... 79.0 2e-12
sp|Q8B912|RPOA_PRRSB Replicase polyprotein 1ab OS=Porcine reprodu... 77.0 8e-12
sp|Q6NYU2|HELZ_DANRE Probable helicase with zinc finger domain OS... 76.6 9e-12
sp|A6YQT5|RPOA_PRRSV Replicase polyprotein 1ab OS=Porcine reprodu... 76.3 1e-11
sp|Q9WJB2|RPOA_PRRSR Replicase polyprotein 1ab OS=Porcine reprodu... 75.5 3e-11
sp|Q9YN02|RPOA_PRRS1 Replicase polyprotein 1ab OS=Porcine reprodu... 74.7 4e-11
sp|Q4R678|GDAP2_MACFA Ganglioside-induced differentiation-associa... 72.8 6e-11
sp|Q68772|RPOA_SHFV Replicase polyprotein 1ab OS=Simian hemorrhag... 73.2 1e-10
sp|Q460N3|PAR15_HUMAN Protein mono-ADP-ribosyltransferase PARP15 ... 72.4 1e-10
sp|Q6J5K9|ARMI_DROME Probable RNA helicase armi OS=Drosophila mel... 71.6 3e-10
sp|O74465|HRR1_SCHPO Helicase required for RNAi-mediated heteroch... 69.3 1e-09
sp|A0MD28|RPOA_PRRSS Replicase polyprotein 1ab OS=Porcine reprodu... 69.3 2e-09
sp|Q8CCK0|H2AW_MOUSE Core histone macro-H2A.2 OS=Mus musculus OX=... 67.4 2e-09
sp|Q9P0M6|H2AW_HUMAN Core histone macro-H2A.2 OS=Homo sapiens OX=... 67.4 2e-09
sp|Q04561|RPOA_PRRSL Replicase polyprotein 1ab OS=Porcine reprodu... 68.6 3e-09
sp|F6QXW0|DNA2_XENTR DNA replication ATP-dependent helicase/nucle... 67.8 4e-09
sp|Q7JUR6|GDAP2_DROME Protein GDAP2 homolog OS=Drosophila melanog... 66.6 6e-09
sp|Q8CFQ3|AQR_MOUSE RNA helicase aquarius OS=Mus musculus OX=1009... 67.4 7e-09
sp|O60306|AQR_HUMAN RNA helicase aquarius OS=Homo sapiens OX=9606... 67.4 7e-09
sp|A0A0D2UG83|H2AY_CAPO3 Histone macroH2A1.1 OS=Capsaspora owczar... 65.1 1e-08
sp|Q292F9|GDAP2_DROPS Protein GDAP2 homolog OS=Drosophila pseudoo... 65.9 1e-08
sp|Q9YLR1|POLN_HEVUS Non-structural polyprotein pORF1 OS=Hepatiti... 65.9 2e-08
sp|P19811|RPOA_EAVBU Replicase polyprotein 1ab OS=Equine arteriti... 65.9 2e-08
sp|Q06502|RPOA_LDVC Replicase polyprotein 1ab OS=Lactate dehydrog... 65.1 3e-08
sp|Q83017|RPOA_LDVP Replicase polyprotein 1ab OS=Lactate dehydrog... 63.2 1e-07
sp|P42694|HELZ_HUMAN Probable helicase with zinc finger domain OS... 62.4 2e-07
sp|Q6DFV5|HELZ_MOUSE Probable helicase with zinc finger domain OS... 62.4 2e-07
sp|Q81862|POLN_HEVCH Non-structural polyprotein pORF1 OS=Hepatiti... 61.6 4e-07
sp|P33424|POLN_HEVPA Non-structural polyprotein pORF1 OS=Hepatiti... 61.2 4e-07
sp|P29324|POLN_HEVBU Non-structural polyprotein pORF1 OS=Hepatiti... 61.2 4e-07
sp|Q6J8G2|POLN_HEVMG Non-structural polyprotein pORF1 OS=Hepatiti... 60.1 1e-06
sp|Q9WC28|POLN_HEVHY Non-structural polyprotein pORF1 OS=Hepatiti... 58.9 2e-06
sp|Q9M041|BH140_ARATH Transcription factor bHLH140 OS=Arabidopsis... 58.5 2e-06
sp|Q03495|POLN_HEVME Non-structural polyprotein pORF1 OS=Hepatiti... 58.5 3e-06
sp|Q04610|POLN_HEVMY Non-structural polyprotein pORF1 OS=Hepatiti... 57.8 5e-06
sp|Q9IVZ9|POLN_HEVCT Non-structural polyprotein pORF1 OS=Hepatiti... 57.8 5e-06
sp|P18479|POLG_ZYMVC Genome polyprotein OS=Zucchini yellow mosaic... 57.8 5e-06
sp|P47386|Y140_MYCGE Uncharacterized ATP-dependent helicase MG140... 55.1 3e-05
sp|P18478|POLG_WMV2U Genome polyprotein (Fragment) OS=Watermelon ... 53.9 7e-05
sp|Q54PT1|GDAP2_DICDI Protein GDAP2 homolog OS=Dictyostelium disc... 53.5 7e-05
sp|Q9J942|RDRP_TRVPP Replicase large subunit OS=Tobacco rattle vi... 53.9 8e-05
sp|P05080|194K_TRVSY Replicase large subunit OS=Tobacco rattle vi... 53.9 8e-05
sp|P08411|POLN_SFV Polyprotein P1234 OS=Semliki forest virus OX=1... 53.5 1e-04
sp|Q89330|POLG_ZYMVR Genome polyprotein OS=Zucchini yellow mosaic... 53.5 1e-04
sp|O36979|POLG_ZYMVS Genome polyprotein OS=Zucchini yellow mosaic... 53.2 1e-04
sp|P75033|Y153_MYCPN Uncharacterized ATP-dependent helicase MG140... 52.4 2e-04
sp|P89659|RDRP_ORSVC Replicase large subunit OS=Odontoglossum rin... 51.6 4e-04
sp|P69514|RDRP_CGMVS Replicase large subunit OS=Cucumber green mo... 50.5 8e-04
sp|Q01901|POLG_PRSVH Genome polyprotein OS=Papaya ringspot virus ... 50.1 0.001
sp|Q5UQ92|YR530_MIMIV Uncharacterized protein R530 OS=Acanthamoeb... 48.9 0.002
sp|Q89AB2|RECD_BUCBP RecBCD enzyme subunit RecD OS=Buchnera aphid... 48.1 0.003
sp|Q9YRB3|RDRP_NCBVS Methyltransferase/helicase/RNA-directed RNA ... 48.5 0.003
sp|P20127|POLR_OYMV RNA replicase polyprotein OS=Ononis yellow mo... 48.5 0.004
sp|Q9QBU0|RDRP_PMTVS Replicase large subunit OS=Potato mop-top vi... 48.5 0.004
sp|O56075|POLG_PEMVM Genome polyprotein OS=Peanut mottle virus (s... 48.1 0.004
sp|Q67724|RDRP_HASV Methyltransferase/helicase/RNA-directed RNA p... 47.8 0.005
sp|Q84133|RDRP_ORSVS Replicase large subunit OS=Odontoglossum rin... 47.8 0.005
sp|Q01681|POLG_PPVEA Genome polyprotein (Fragment) OS=Plum pox po... 47.8 0.006
sp|P09814|POLG_TVMV Genome polyprotein OS=Tobacco vein mottling v... 47.4 0.007
sp|P17766|POLG_PPVNA Genome polyprotein OS=Plum pox potyvirus (is... 46.6 0.011
sp|Q90069|POLG_SBMVG Genome polyprotein OS=Soybean mosaic virus (... 46.6 0.014
sp|Q05983|RDRP_RBDVR Methyltransferase/helicase/RNA-directed RNA ... 46.2 0.016
sp|P13529|POLG_PPVD Genome polyprotein OS=Plum pox potyvirus (str... 45.8 0.020
sp|P17767|POLG_PPVRA Genome polyprotein OS=Plum pox potyvirus (st... 45.8 0.022
sp|Q5GS59|RLME_WOLTR Ribosomal RNA large subunit methyltransferas... 43.9 0.023
sp|P17765|POLG_BYMV Genome polyprotein OS=Bean yellow mosaic viru... 45.1 0.035
sp|Q65399|POLG_BCMNN Genome polyprotein OS=Bean common mosaic nec... 45.1 0.038
sp|Q83044|R1A_LIYV9 Replicase polyprotein 1a OS=Lettuce infectiou... 45.1 0.040
sp|P21231|POLG_SBMVN Genome polyprotein OS=Soybean mosaic virus (... 44.7 0.043
sp|Q84934|POLG_PPVSK Genome polyprotein OS=Plum pox potyvirus (st... 44.7 0.050
sp|Q83045|R1AB_LIYV9 Replicase polyprotein 1ab OS=Lettuce infecti... 44.7 0.051
sp|Q5HTX9|PGLB_CAMJR Undecaprenyl-diphosphooligosaccharide--prote... 43.9 0.062
sp|Q0P9C8|PGLB_CAMJE Undecaprenyl-diphosphooligosaccharide--prote... 43.9 0.063
sp|Q58914|Y1519_METJA Uncharacterized protein MJ1519 OS=Methanoca... 43.9 0.085
sp|Q9RT63|RECD2_DEIRA ATP-dependent RecD2 DNA helicase OS=Deinoco... 43.5 0.087
sp|Q9Z1Q1|NEST_MESAU Nestin (Fragments) OS=Mesocricetus auratus O... 43.5 0.10
sp|Q73L97|RLME_TREDE Ribosomal RNA large subunit methyltransferas... 41.6 0.12
sp|P32270|DDA_BPT4 ATP-dependent DNA helicase dda OS=Enterobacter... 42.8 0.12
sp|Q5A1V3|POA1_CANAL ADP-ribose 1''-phosphate phosphatase OS=Cand... 40.8 0.12
sp|Q73IS9|RLME_WOLPM Ribosomal RNA large subunit methyltransferas... 41.2 0.13
sp|P45612|UVRD_MYCCT Probable DNA helicase II homolog OS=Mycoplas... 42.8 0.13
sp|A0QS28|RECD_MYCS2 RecBCD enzyme subunit RecD OS=Mycolicibacter... 42.4 0.17
sp|Q9YKD6|RDRP_TOMS1 Replicase large subunit OS=Tomato mosaic vir... 42.8 0.19
sp|Q9ILI5|NS1AB_TASV2 Non-structural polyprotein 1AB OS=Turkey as... 42.4 0.22
sp|A8GUJ3|ATP6_RICB8 ATP synthase subunit a OS=Rickettsia bellii ... 41.2 0.22
sp|P17595|ALPHA_BSMV Replication protein alpha-A OS=Barley stripe... 42.4 0.23
sp|Q1RGZ3|ATP6_RICBR ATP synthase subunit a OS=Rickettsia bellii ... 41.2 0.23
sp|Q89249|RDRP_SBWMN Replicase large subunit OS=Soil-borne wheat ... 42.0 0.34
sp|Q03QN6|TIG_LEVBA Trigger factor OS=Levilactobacillus brevis (s... 41.2 0.36
sp|B9KDD4|PGLB_CAMLR Undecaprenyl-diphosphooligosaccharide--prote... 41.2 0.39
sp|Q03F26|TIG_PEDPA Trigger factor OS=Pediococcus pentosaceus (st... 41.2 0.41
sp|P20234|POLG_OMV Genome polyprotein (Fragment) OS=Ornithogalum ... 41.6 0.43
sp|B0ULY1|ATP6_METS4 ATP synthase subunit a OS=Methylobacterium s... 40.1 0.51
sp|Q4FRM3|RS20_PSYA2 Small ribosomal subunit protein bS20 OS=Psyc... 37.4 0.51
sp|P89676|RDRP_TOMK2 Replicase large subunit OS=Tomato mosaic vir... 41.2 0.53
sp|Q9Q1T8|RDRP_TOMK1 Replicase large subunit OS=Tomato mosaic vir... 41.2 0.55
sp|P03587|RDRP_TOML Replicase large subunit OS=Tomato mosaic viru... 41.2 0.56
sp|Q11KH9|ATP6_CHESB ATP synthase subunit a OS=Chelativorans sp. ... 39.7 0.61
sp|Q6XW15|POLG_BTMV Genome polyprotein OS=Beet mosaic virus OX=11... 40.8 0.70
sp|O11436|POLG_RGMVD Genome polyprotein OS=Ryegrass mosaic virus ... 40.8 0.76
sp|P29152|POLG_PSBMV Genome polyprotein OS=Pea seed-borne mosaic ... 40.4 0.88
sp|Q64962|RDRP_ASPVP RNA replication polyprotein OS=Apple stem pi... 40.4 0.93
sp|Q84687|RDRP_PCV87 Replicase large subunit OS=Peanut clump viru... 40.4 0.93
sp|P41299|NU5M_BALMU NADH-ubiquinone oxidoreductase chain 5 OS=Ba... 40.1 0.97
sp|P39369|YJHR_ECOLI Putative uncharacterized protein YjhR OS=Esc... 39.7 1.0
sp|Q8K9A8|RECD_BUCAP RecBCD enzyme subunit RecD OS=Buchnera aphid... 40.1 1.1
sp|Q2KBW1|ATP6_RHIEC ATP synthase subunit a OS=Rhizobium etli (st... 38.9 1.1
sp|Q08534|R1AB_BYVU Replicase polyprotein 1ab OS=Beet yellows vir... 39.7 1.5
sp|P15576|NU1M_LEITA NADH-ubiquinone oxidoreductase chain 1 OS=Le... 38.9 1.7
sp|P22706|TRAI2_ECOLX Multifunctional conjugation protein TraI OS... 39.7 1.7
sp|P19723|POLG_PRSVP Genome polyprotein (Fragment) OS=Papaya ring... 39.3 1.8
sp|Q58889|PRS2_METJA Putative 26S proteasome regulatory subunit h... 38.9 1.9
sp|Q83943|1A_OLV2I Replication protein 1a OS=Olive latent virus 2... 39.3 1.9
sp|Q14151|SAFB2_HUMAN Scaffold attachment factor B2 OS=Homo sapie... 39.3 1.9
sp|P24978|NU5M_BALPH NADH-ubiquinone oxidoreductase chain 5 OS=Ba... 38.9 2.0
sp|Q5NQH8|RLME_ZYMMO Ribosomal RNA large subunit methyltransferas... 38.1 2.1
sp|Q3KNA1|MRGB2_MOUSE Mas-related G-protein coupled receptor memb... 38.5 2.3
sp|P18247|POLG_PVYN Genome polyprotein OS=Potato virus Y (strain ... 39.3 2.3
sp|Q91ZC6|MRGA6_MOUSE Mas-related G-protein coupled receptor memb... 38.1 2.6
sp|Q2FQC0|KUP_METHJ Probable potassium transport system protein K... 38.5 2.6
sp|A1SSX2|RNFD_PSYIN Ion-translocating oxidoreductase complex sub... 38.1 2.6
sp|P19724|POLG_PRSVW Genome polyprotein (Fragment) OS=Papaya ring... 38.5 2.8
sp|F1QGD2|ZDH24_DANRE Probable palmitoyltransferase ZDHHC24 OS=Da... 38.1 2.8
sp|Q9YQ08|RDRP_TMVB Replicase large subunit OS=Tobacco mosaic vir... 38.9 2.9
sp|Q12019|MDN1_YEAST Midasin OS=Saccharomyces cerevisiae (strain ... 38.9 3.0
sp|B3PRF6|ATP6_RHIE6 ATP synthase subunit a OS=Rhizobium etli (st... 37.7 3.1
sp|Q9WAL8|POL1_SDVS5 RNA1 polyprotein OS=Satsuma dwarf virus (iso... 38.5 3.2
sp|Q8IRB5|CLSPN_DROME Claspin OS=Drosophila melanogaster OX=7227 ... 38.5 3.2
sp|Q1MKT2|ATP6_RHIJ3 ATP synthase subunit a OS=Rhizobium johnston... 37.7 3.3
sp|P12428|BROWN_DROME Protein brown OS=Drosophila melanogaster OX... 38.5 3.3
sp|B5ZS16|ATP6_RHILW ATP synthase subunit a OS=Rhizobium legumino... 37.4 3.5
sp|B9JA28|ATP6_RHIR8 ATP synthase subunit a OS=Rhizobium rhizogen... 37.4 3.5
sp|C3MGQ4|RLME_SINFN Ribosomal RNA large subunit methyltransferas... 37.4 4.2
sp|Q67704|RDRP_GVAIS RNA replication protein OS=Grapevine virus A... 38.1 4.5
sp|A5N5W0|PANB_CLOK5 3-methyl-2-oxobutanoate hydroxymethyltransfe... 37.4 4.6
sp|P0DW67|RGYR2_SULAC Reverse gyrase 2 OS=Sulfolobus acidocaldari... 37.7 4.9
sp|A5E287|POA1_LODEL ADP-ribose 1''-phosphate phosphatase OS=Lodd... 36.2 4.9
sp|P14565|TRAI1_ECOLI Multifunctional conjugation protein TraI OS... 37.7 5.2
sp|Q68XQ1|ATP6_RICTY ATP synthase subunit a OS=Rickettsia typhi (... 37.0 5.2
sp|Q7VQM8|RLME_BLOFL Ribosomal RNA large subunit methyltransferas... 36.6 5.2
sp|O94500|NDUV1_SCHPO NADH-ubiquinone oxidoreductase 51 kDa subun... 37.4 5.5
sp|Q66121|1A_CMVIX Replication protein 1a OS=Cucumber mosaic viru... 37.7 5.7
sp|Q54VA8|TRM7_DICDI Putative tRNA (cytidine(32)/guanosine(34)-2'... 37.0 5.7
sp|P90211|RDRP_TMOB Replicase large subunit OS=Tobamovirus Ob OX=... 37.7 6.0
sp|Q58990|Y1595_METJA UPF0104 membrane protein MJ1595 OS=Methanoc... 37.0 6.1
sp|B5RRC2|MRAY_BORRA Phospho-N-acetylmuramoyl-pentapeptide-transf... 37.0 6.1
sp|P14879|PYR4_MICDP Phycobilisome 31.6 kDa linker polypeptide, p... 37.0 6.2
sp|Q6CRE9|FYV8_KLULA Protein FYV8 OS=Kluyveromyces lactis (strain... 37.4 6.5
sp|P30738|RDRP_TMVKR Replicase large subunit OS=Tobacco mosaic vi... 37.7 6.5
sp|Q65674|TGB1_BNYVS Movement protein TGB1 OS=Beet necrotic yello... 37.0 6.6
sp|A0A0S2T050|RDRP_TBRFV Replicase large subunit OS=Tomato brown ... 37.4 6.7
sp|Q67ES1|TR113_RAT Taste receptor type 2 member 113 OS=Rattus no... 36.6 7.1
sp|A8GLV8|ATP6_RICAH ATP synthase subunit a OS=Rickettsia akari (... 36.6 7.2
sp|Q04574|POL1_BAYMG Genome polyprotein 1 OS=Barley yellow mosaic... 37.4 7.6
sp|P04540|NU5M_TRYBB NADH-ubiquinone oxidoreductase chain 5 OS=Tr... 37.0 7.8
sp|Q98745|RDRP_TMVRA Replicase large subunit OS=Tobacco mosaic vi... 37.4 7.8
sp|B5RLC9|MRAY_BORDL Phospho-N-acetylmuramoyl-pentapeptide-transf... 36.6 8.1
sp|P03586|RDRP_TMV Replicase large subunit OS=Tobacco mosaic viru... 37.4 8.1
sp|O93058|RDRP_TMVOM Replicase large subunit OS=Tobacco mosaic vi... 37.4 8.3
sp|Q00167|VG78_ICHVA Putative zinc-binding protein ORF78 OS=Ictal... 36.6 8.3
sp|Q9M6N7|AMT2_ARATH Ammonium transporter 2 OS=Arabidopsis thalia... 37.0 8.4
sp|D0E0C2|SCNA1_PERAM Sodium channel protein PaFPC1 OS=Periplanet... 37.4 8.5
sp|A8F0C9|ATP6_RICM5 ATP synthase subunit a OS=Rickettsia massili... 36.2 9.5
sp|P54334|XKDO_BACSU Phage-like element PBSX protein XkdO OS=Baci... 37.0 9.5
sp|Q6Q487|CALX_ASPFU Calnexin homolog OS=Aspergillus fumigatus (s... 36.6 10.0
>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score = 10399 bits (26985), Expect = 0.0, Method: Composition-based stats.
Identities = 6113/7103 (86%), Positives = 6585/7103 (93%), Gaps = 37/7103 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA + HGH +VELVAE++GIQYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGK+ CTLSEQLD+I++KRGVYCCR+HEHEIAW
Sbjct 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVASP ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + E+GPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+Q+S+L+PL F S+A
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIF+RTL+ A +S+ LQ+AA+TILDGIS+ SLRL+DAM++TSDL TN++++MAY
Sbjct 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ TSQWL+N+ GT EKL+P+ +W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVC+NGLMLLEIKD E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV EVQGYK+V
Sbjct 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ-YEYGTEDDYQGK 958
WS+AT+YLFD++GE +S MYCSFYPPDE+EE+ EEE T +EYGTEDDYQG
Sbjct 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
Query 959 PLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
PLEFGA++ ++ EEE+EEDWLDD ++Q+
Sbjct 961 PLEFGASAETVRVEEEEEEDWLDDTTEQSE------------------------IEPEPE 996
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
VN F+GYLKLTDNV IK DIV+EA+ P V+VNAAN++LKHGGGVAGALNKA
Sbjct 997 PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKA 1056
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
TN AMQ ESDDYI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYENF
Sbjct 1057 TNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENF 1116
Query 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
N ++LLAPLLSAGIFGA P+ SL+VCV TVRT VY+AV DK LY+++V +L+ +
Sbjct 1117 NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPR- 1175
Query 1199 VEQKIAEIPKEEVKPFI----TESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLL 1254
E PK+E P TE K V++ KIKAC++EVTTTLEETKFLT LL
Sbjct 1176 -----VEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLL 1230
Query 1255 LYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLA 1314
L+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML+
Sbjct 1231 LFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLS 1290
Query 1315 KALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWN 1374
+AL+KVP D YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSWN
Sbjct 1291 RALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWN 1350
Query 1375 LREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASL 1434
LREMLAHAEETRKLMP+C++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS+
Sbjct 1351 LREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASI 1410
Query 1435 INTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS 1494
I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSSS
Sbjct 1411 ITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSS 1470
Query 1495 KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVITF 1553
KT EEHF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGEV++
Sbjct 1471 KTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSL 1530
Query 1554 DNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSH 1613
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH +H
Sbjct 1531 DKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNH 1590
Query 1614 EGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNN 1673
EGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNN
Sbjct 1591 EGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN 1650
Query 1674 CYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMS 1733
CYL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM+
Sbjct 1651 CYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMT 1710
Query 1734 YLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQA 1793
+L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+ A
Sbjct 1711 HLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDA 1770
Query 1794 TKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALL 1853
T+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA L
Sbjct 1771 TQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHL 1830
Query 1854 TKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPID 1913
TK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPID
Sbjct 1831 TKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPID 1890
Query 1914 LVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYK 1973
LVP QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY+
Sbjct 1891 LVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYR 1950
Query 1974 HYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDA 2033
HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1951 HYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDT 2010
Query 2034 QGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHT 2093
QGMDNLACE +P SEEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+GH
Sbjct 2011 QGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHE 2070
Query 2094 DLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTT 2153
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + TT
Sbjct 2071 DLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITT 2130
Query 2154 TNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEA 2213
+N R RV NYMPY FTLL QLCTFT+STNSRI+AS+PTTIAKN+VKSV K CL+A
Sbjct 2131 SNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
Query 2214 SFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNS 2273
NY+KSP FSKL I +W LLLS+CLGSLI TAA GVL+SN G PSYC G RE YLNS
Sbjct 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNS 2250
Query 2274 TNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYIL 2333
+NVT +C GS PCS+CLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+L
Sbjct 2251 SNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYML 2310
Query 2334 FTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYV 2393
FT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY+
Sbjct 2311 FTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYI 2370
Query 2394 WKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCV 2453
WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC+
Sbjct 2371 WKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCL 2430
Query 2454 NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTY 2513
NCDTFC GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV VKNG++HLYFDKAGQKTY
Sbjct 2431 NCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTY 2490
Query 2514 ERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLD 2573
ERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES++KSASVYYSQLMCQPILLLD
Sbjct 2491 ERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLD 2550
Query 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
QALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF
Sbjct 2551 QALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTF 2610
Query 2634 ISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACID 2693
+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACID
Sbjct 2611 VSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACID 2670
Query 2694 CSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNV 2753
C+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV
Sbjct 2671 CNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNV 2730
Query 2754 VTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAID 2813
+TTKI+LKGGKIV+ K ++K TL+ + A + Y++ PVH +S H +++EIIGYKAI
Sbjct 2731 ITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQ 2790
Query 2814 GGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTI 2873
GVTRDI STD CFANKHA FD WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT+
Sbjct 2791 DGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTV 2850
Query 2874 LRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC 2933
LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYC
Sbjct 2851 LRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYC 2910
Query 2934 YDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
YDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2911 YDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE 2970
Query 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
G+C+STSGRWVLNN++YR+L GVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+
Sbjct 2971 VGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGII 3030
Query 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
AI+VTC AYYFM+FRR FGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYSV YLYLT
Sbjct 3031 AILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLT 3090
Query 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFS 3173
FY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNGV+FS
Sbjct 3091 FYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFS 3150
Query 3174 TFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCH 3233
TFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCH
Sbjct 3151 TFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCH 3210
Query 3234 LAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
LAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL
Sbjct 3211 LAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3270
Query 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
WLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LK
Sbjct 3271 WLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLK 3330
Query 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
VDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGF
Sbjct 3331 VDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGF 3390
Query 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
NIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYA
Sbjct 3391 NIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYA 3450
Query 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKE
Sbjct 3451 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
Query 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
LLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+
Sbjct 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLI 3570
Query 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMV
Sbjct 3571 LVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMV 3630
Query 3654 YMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMN 3713
YMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMN
Sbjct 3631 YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMN 3690
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITG
Sbjct 3691 VITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
NTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+
Sbjct 3751 NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKS 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ
Sbjct 3811 SIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPS 3953
LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPS
Sbjct 3871 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPS 3930
Query 3954 YAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 4013
YAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY
Sbjct 3931 YAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 3990
Query 4014 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4073
KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV
Sbjct 3991 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4050
Query 4074 IPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 4133
+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRA
Sbjct 4051 VPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRA 4110
Query 4134 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKW 4193
NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLKW
Sbjct 4111 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKW 4170
Query 4194 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4253
ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ
Sbjct 4171 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4230
Query 4254 AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
AGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE
Sbjct 4231 AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4290
Query 4314 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVC 4373
ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVC
Sbjct 4291 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 4350
Query 4374 GMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDK 4433
GMWKGYGCSCDQLREP++QSADA +FLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYN+K
Sbjct 4351 GMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEK 4410
Query 4434 VAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDF 4493
VAGFAKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+KDCPAVA HDF
Sbjct 4411 VAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDF 4470
Query 4494 FKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD 4553
FKFR+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD
Sbjct 4471 FKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD 4530
Query 4554 WYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGD 4613
WYDFVENPDILRVYANLGERVRQ+LLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWYDFGD
Sbjct 4531 WYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGD 4590
Query 4614 FIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLK 4673
F+Q PG GVP+VDSYYSLLMPILTLTRAL AESH+D DL KP IKWDLLKYDFTEERL
Sbjct 4591 FVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLC 4650
Query 4674 LFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV 4733
LFDRYFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV
Sbjct 4651 LFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV 4710
Query 4734 VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL 4793
VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL
Sbjct 4711 VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL 4770
Query 4794 TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP 4853
TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP
Sbjct 4771 TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP 4830
Query 4854 TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY 4913
TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY
Sbjct 4831 TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY 4890
Query 4914 EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA 4973
EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA
Sbjct 4891 EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA 4950
Query 4974 TRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARK 5033
TRGATVVIGTSKFYGGWHNMLKTVYSDVE PHLMGWDYPKCDRAMPNMLRIMASLVLARK
Sbjct 4951 TRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARK 5010
Query 5034 HTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT 5093
H TCC+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT
Sbjct 5011 HNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT 5070
Query 5094 ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDD 5153
ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV+EFYAYLRKHFSMMILSDD
Sbjct 5071 ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDD 5130
Query 5154 AVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK 5213
AVVC+NS YA+QGLVASIKNFK+VLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK
Sbjct 5131 AVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK 5190
Query 5214 QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF 5273
QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF
Sbjct 5191 QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF 5250
Query 5274 HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN 5333
HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN
Sbjct 5251 HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN 5310
Query 5334 SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS 5393
SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS
Sbjct 5311 SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS 5370
Query 5394 YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER 5453
YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER
Sbjct 5371 YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER 5430
Query 5454 LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK 5513
LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK
Sbjct 5431 LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK 5490
Query 5514 NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI 5573
NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI
Sbjct 5491 NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI 5550
Query 5574 TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC 5633
TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC
Sbjct 5551 TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC 5610
Query 5634 SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD 5693
SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD
Sbjct 5611 SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD 5670
Query 5694 IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM 5753
IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM
Sbjct 5671 IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM 5730
Query 5754 KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN 5813
KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN
Sbjct 5731 KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN 5790
Query 5814 RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT 5873
RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT
Sbjct 5791 RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT 5850
Query 5874 TETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF 5933
TETAHSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF
Sbjct 5851 TETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF 5910
Query 5934 KDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG 5993
KDCSK+ITGLHPTQAPTHLSVD KFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG
Sbjct 5911 KDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG 5970
Query 5994 YPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTP 6053
YPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAVPTGYVDT
Sbjct 5971 YPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTE 6030
Query 6054 NNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAH 6113
NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFVLWAH
Sbjct 6031 NNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAH 6090
Query 6114 GFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWG 6173
GFELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPFMIDVQQWG
Sbjct 6091 GFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWG 6150
Query 6174 FTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAA 6233
FTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDEL++N+A
Sbjct 6151 FTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSA 6210
Query 6234 CRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFY 6293
CRKVQHMVVK+ALLADKFPVLHDIGNPKAIKCVPQA+VEWKFYDAQPCSDKAYKIEELFY
Sbjct 6211 CRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFY 6270
Query 6294 SYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT 6353
SYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT
Sbjct 6271 SYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT 6330
Query 6354 PAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA 6413
PAFDKSAF NLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA
Sbjct 6331 PAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA 6390
Query 6414 NEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGE 6473
NEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQSLENVA+NVVNKGHFDG GE
Sbjct 6391 NEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGE 6450
Query 6474 VPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAA 6533
PVSIINN VYTKVDG+DVE+FENKTTLPVNVAFELWAKRNIKPVPE+KILNNLGVDIAA
Sbjct 6451 APVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAA 6510
Query 6534 NTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGV 6593
NTVIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ LTV FDGRV+GQVDLFRNARNGV
Sbjct 6511 NTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGV 6570
Query 6594 LITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQ 6653
LITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQSR+L+
Sbjct 6571 LITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLE 6630
Query 6654 EFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKES 6713
+FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR ++S
Sbjct 6631 DFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDS 6690
Query 6714 PFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVT 6773
P +LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV+SKVVKVT
Sbjct 6691 PLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVT 6750
Query 6774 IDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSAT 6833
IDY EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG++A
Sbjct 6751 IDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAV 6810
Query 6834 LPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL 6893
+PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL
Sbjct 6811 IPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL 6870
Query 6894 VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICG 6953
VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDP+TK+VTKENDSKEGFFTY+CG
Sbjct 6871 VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCG 6930
Query 6954 FIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKP 7013
FI+QKLALGGS+A+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NYLGKP
Sbjct 6931 FIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKP 6990
Query 7014 REQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLL 7073
+EQIDGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI SLL
Sbjct 6991 KEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLL 7050
Query 7074 SKGRLIIRENNRVVISSDVLVNN 7096
KGRLIIRENNRVV+SSD+LVNN
Sbjct 7051 EKGRLIIRENNRVVVSSDILVNN 7073
>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1
SV=1
Length=7096
Score = 10373 bits (26918), Expect = 0.0, Method: Composition-based stats.
Identities = 7096/7096 (100%), Positives = 7096/7096 (100%), Gaps = 0/7096 (0%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV
Sbjct 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK
Sbjct 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW
Sbjct 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI
Sbjct 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL
Sbjct 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC
Sbjct 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF
Sbjct 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA
Sbjct 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY
Sbjct 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV
Sbjct 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC
Sbjct 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG
Sbjct 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN 840
TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN
Sbjct 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN 840
Query 841 ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW 900
ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW
Sbjct 841 ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW 900
Query 901 SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL 960
SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL
Sbjct 901 SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL 960
Query 961 EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV 1020
EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV
Sbjct 961 EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV 1020
Query 1021 QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN
Sbjct 1021 QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
Query 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ 1140
NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ
Sbjct 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ 1140
Query 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE 1200
HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE
Sbjct 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE 1200
Query 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN 1260
QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN
Sbjct 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN 1260
Query 1261 GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV 1320
GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV
Sbjct 1261 GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV 1320
Query 1321 PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA 1380
PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA
Sbjct 1321 PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA 1380
Query 1381 HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND 1440
HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND
Sbjct 1381 HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND 1440
Query 1441 LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH 1500
LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH
Sbjct 1441 LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH 1500
Query 1501 FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL 1560
FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL
Sbjct 1501 FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL 1560
Query 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV
Sbjct 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
Query 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL
Sbjct 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
Query 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN
Sbjct 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
Query 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ
Sbjct 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
Query 1801 ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK 1860
ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK
Sbjct 1801 ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK 1860
Query 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY 1920
GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY
Sbjct 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY 1920
Query 1921 PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK
Sbjct 1921 PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
Query 1981 KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA 2040
KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA
Sbjct 1981 KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA 2040
Query 2041 CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV
Sbjct 2041 CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
Query 2101 DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC 2160
DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC
Sbjct 2101 DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC 2160
Query 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS
Sbjct 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
Query 2221 PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT 2280
PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT
Sbjct 2221 PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT 2280
Query 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV
Sbjct 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
Query 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV
Sbjct 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA
Sbjct 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH
Sbjct 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV
Sbjct 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG
Sbjct 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
Query 2641 FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN 2700
FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN
Sbjct 2641 FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN 2700
Query 2701 AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL 2760
AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL
Sbjct 2701 AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL 2760
Query 2761 KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI 2820
KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI
Sbjct 2761 KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI 2820
Query 2821 ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD 2880
ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD
Sbjct 2821 ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD 2880
Query 2881 FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE 2940
FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE
Sbjct 2881 FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE 2940
Query 2941 GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST 3000
GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST
Sbjct 2941 GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST 3000
Query 3001 SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL
Sbjct 3001 SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
Query 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV
Sbjct 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
Query 3121 SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL 3180
SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL
Sbjct 3121 SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL 3180
Query 3181 CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND 3240
CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND
Sbjct 3181 CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND 3240
Query 3241 FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY 3300
FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY
Sbjct 3241 FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY 3300
Query 3301 CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK 3360
CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK
Sbjct 3301 CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK 3360
Query 3361 TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV 3420
TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV
Sbjct 3361 TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV 3420
Query 3421 SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR 3480
SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR
Sbjct 3421 SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR 3480
Query 3481 WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN
Sbjct 3481 WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
Query 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW
Sbjct 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
Query 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV
Sbjct 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
Query 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK
Sbjct 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
Query 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM
Sbjct 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
Query 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL
Sbjct 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
Query 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL
Sbjct 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
Query 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA
Sbjct 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
Query 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED
Sbjct 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
Query 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY
Sbjct 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
Query 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ 4140
KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ
Sbjct 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ 4140
Query 4141 NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD 4200
NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD
Sbjct 4141 NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD 4200
Query 4201 GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV 4260
GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV
Sbjct 4201 GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV 4260
Query 4261 PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES 4320
PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES
Sbjct 4261 PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES 4320
Query 4321 FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG 4380
FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG
Sbjct 4321 FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG 4380
Query 4381 CSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKF 4440
CSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKF
Sbjct 4381 CSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKF 4440
Query 4441 LKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDG 4500
LKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDG
Sbjct 4441 LKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDG 4500
Query 4501 DMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVEN 4560
DMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVEN
Sbjct 4501 DMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVEN 4560
Query 4561 PDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPG 4620
PDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPG
Sbjct 4561 PDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPG 4620
Query 4621 SGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFK 4680
SGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFK
Sbjct 4621 SGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFK 4680
Query 4681 YWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHF 4740
YWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHF
Sbjct 4681 YWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHF 4740
Query 4741 RELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQ 4800
RELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQ
Sbjct 4741 RELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQ 4800
Query 4801 TVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQ 4860
TVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQ
Sbjct 4801 TVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQ 4860
Query 4861 LLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALF 4920
LLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALF
Sbjct 4861 LLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALF 4920
Query 4921 AYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVV 4980
AYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVV
Sbjct 4921 AYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVV 4980
Query 4981 IGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSL 5040
IGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSL
Sbjct 4981 IGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSL 5040
Query 5041 SHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALL 5100
SHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALL
Sbjct 5041 SHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALL 5100
Query 5101 STDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNS 5160
STDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNS
Sbjct 5101 STDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNS 5160
Query 5161 TYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVY 5220
TYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVY
Sbjct 5161 TYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVY 5220
Query 5221 LPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYI 5280
LPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYI
Sbjct 5221 LPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYI 5280
Query 5281 RKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRC 5340
RKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRC
Sbjct 5281 RKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRC 5340
Query 5341 GACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHK 5400
GACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHK
Sbjct 5341 GACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHK 5400
Query 5401 PPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAE 5460
PPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAE
Sbjct 5401 PPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAE 5460
Query 5461 TLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIG 5520
TLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIG
Sbjct 5461 TLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIG 5520
Query 5521 EYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTL 5580
EYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTL
Sbjct 5521 EYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTL 5580
Query 5581 NISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDA 5640
NISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDA
Sbjct 5581 NISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDA 5640
Query 5641 LCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEI 5700
LCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEI
Sbjct 5641 LCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEI 5700
Query 5701 SMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDM 5760
SMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDM
Sbjct 5701 SMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDM 5760
Query 5761 FLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVV 5820
FLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVV
Sbjct 5761 FLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVV 5820
Query 5821 REFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC 5880
REFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC
Sbjct 5821 REFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC 5880
Query 5881 NVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVI 5940
NVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVI
Sbjct 5881 NVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVI 5940
Query 5941 TGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFIT 6000
TGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFIT
Sbjct 5941 TGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFIT 6000
Query 6001 REEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSR 6060
REEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSR
Sbjct 6001 REEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSR 6060
Query 6061 VSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSM 6120
VSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSM
Sbjct 6061 VSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSM 6120
Query 6121 KYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQS 6180
KYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQS
Sbjct 6121 KYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQS 6180
Query 6181 NHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHM 6240
NHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHM
Sbjct 6181 NHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHM 6240
Query 6241 VVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSD 6300
VVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSD
Sbjct 6241 VVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSD 6300
Query 6301 KFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSA 6360
KFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSA
Sbjct 6301 KFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSA 6360
Query 6361 FVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYL 6420
FVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYL
Sbjct 6361 FVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYL 6420
Query 6421 DAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIIN 6480
DAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIIN
Sbjct 6421 DAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIIN 6480
Query 6481 NTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDY 6540
NTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDY
Sbjct 6481 NTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDY 6540
Query 6541 KRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSV 6600
KRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSV
Sbjct 6541 KRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSV 6600
Query 6601 KGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQ 6660
KGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQ
Sbjct 6601 KGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQ 6660
Query 6661 MEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDF 6720
MEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDF
Sbjct 6661 MEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDF 6720
Query 6721 IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEIS 6780
IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEIS
Sbjct 6721 IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEIS 6780
Query 6781 FMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMM 6840
FMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMM
Sbjct 6781 FMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMM 6840
Query 6841 NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND 6900
NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND
Sbjct 6841 NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND 6900
Query 6901 FVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLA 6960
FVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLA
Sbjct 6901 FVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLA 6960
Query 6961 LGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGY 7020
LGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGY
Sbjct 6961 LGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGY 7020
Query 7021 VMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLII 7080
VMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLII
Sbjct 7021 VMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLII 7080
Query 7081 RENNRVVISSDVLVNN 7096
RENNRVVISSDVLVNN
Sbjct 7081 RENNRVVISSDVLVNN 7096
>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079
Score = 10328 bits (26802), Expect = 0.0, Method: Composition-based stats.
Identities = 6091/7106 (86%), Positives = 6566/7106 (92%), Gaps = 37/7106 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESL G +EKTHVQLSLPVLQVRDVLVRGFGDSVEE L+EAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLALGVSEKTHVQLSLPVLQVRDVLVRGFGDSVEEALAEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA+ HG+ +VELVAEL+GIQYGRSG TLGVLVPHVGE PVAYR
Sbjct 61 LPQLEQPYVFIKRSDAQGTNHGYKVVELVAELDGIQYGRSGTTLGVLVPHVGETPVAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLG ELGTDP ED+++NWNTKH GV REL+RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGVELGTDPIEDYEQNWNTKHGGGVLRELIRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A+TRYVDNNFCGPDGYPLECIKDLLARAGK+ CTLSEQLD+I++KRGVYCCREHEHEI W
Sbjct 181 AFTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERSEKSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSEKSYERQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + EVGPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PANAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIG +HTG+ G+ E LN++L+EIL +++VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASANIGASHTGITGDNVETLNEDLMEILNRDRVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SAST AFV+TVKGLDYK FK IVESCGNFKVT+G+AKKGAWNIG++KSIL+PLY F S+A
Sbjct 481 SASTCAFVDTVKGLDYKTFKDIVESCGNFKVTRGRAKKGAWNIGQEKSILTPLYGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIF+R L+TA +S+ LQ+AAITILDGIS+ SLRLIDAM++TSDL TN+++VMAY
Sbjct 541 AGVIRSIFTRALDTANHSIPDLQRAAITILDGISEQSLRLIDAMVYTSDLLTNSVIVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ +QWL+N+ GT +KLKPV W+E K G+EFLRD WEI+KF+ T +IV
Sbjct 601 VTGGLVQQITQWLSNMLGTTVDKLKPVFTWVEAKLSAGIEFLRDAWEILKFLVTGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + +KE V+ F ++NK L +C D +II GAKL+ LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNLKECVKAFLDVLNKALEMCIDQVIIAGAKLRTLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPL+APKE+ F EG++ T +EEVVLK G+L+ LE P ++G
Sbjct 721 IRGKEQLQLLMPLRAPKEVTFFEGDSHDTVFTSEEVVLKNGELEALETPVDSFTNGAVIG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVC+NGLMLLE+KD E+YCAL+P ++ TNN F+LKGGAP K VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCVNGLMLLELKDKEQYCALSPGLLATNNVFSLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 KITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ--YEYGTEDDYQG 957
WS+AT+YLFD++GE KL+S MYCSFYPPDE+E+ + E+EE P +EYGTEDDY+G
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCEEYEDEEEIPEETCEHEYGTEDDYKG 960
Query 958 KPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELT 1017
PLEFGA++ QQ +++ + + E
Sbjct 961 LPLEFGASTE----------------IQQVDEEEEEDWLEEAIAAKPEPEP--------- 995
Query 1018 PVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
+ VN F+GYLKLTDNV IK DIV+EA+ KPTV+VNAANV+LKHGGGVAGALNK
Sbjct 996 --LPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQHAKPTVIVNAANVHLKHGGGVAGALNK 1053
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
ATN AMQ ESDDYI NGPL VGGSC+LSGHNLAK C+HVVGPN+N GED+QLLK+AY N
Sbjct 1054 ATNGAMQQESDDYIKKNGPLTVGGSCLLSGHNLAKKCMHVVGPNLNAGEDVQLLKAAYAN 1113
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK 1197
FN +VLLAPLLSAGIFGA P+ SL++CV+TVRT VY AV D++LYD +V +L+ K
Sbjct 1114 FNSQDVLLAPLLSAGIFGAKPLQSLKMCVETVRTQVYFAVNDQDLYDHVVLGYLDSLKPK 1173
Query 1198 --QVEQKIAEIPKEEVKPFITESKPSVEQ----RKQDDKKIKACVEEVTTTLEETKFLTE 1251
Q+ E+ ++ +T+ +E+ K D K KA +EEV T+LEETKFLT
Sbjct 1174 VETPTQENLELKEQPAVETLTQENLELEELPVIEKPVDVKFKARIEEVNTSLEETKFLTS 1233
Query 1252 NLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTE 1311
LLL+ DING L+ DS ++ D+ FL+KDAPYIVGDV+ G +T V+IP KKAGGTTE
Sbjct 1234 RLLLFADINGKLYQDSQNMLRGEDMFFLEKDAPYIVGDVISSGDITCVIIPAKKAGGTTE 1293
Query 1312 MLAKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTV 1371
MLAKAL+KVP YITTYPGQG GYT+EEAKT L+KCKS FY+LPS N+K+EILGTV
Sbjct 1294 MLAKALKKVPVSEYITTYPGQGCAGYTLEEAKTALRKCKSVFYVLPSKTPNDKEEILGTV 1353
Query 1372 SWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTV 1431
SWNLREMLAHAEETRKLM +C++ KA++STI R+YKGIK+QEG+VDYG RF+FYTSK V
Sbjct 1354 SWNLREMLAHAEETRKLMLICMDVKALMSTIHRRYKGIKVQEGIVDYGVRFFFYTSKEPV 1413
Query 1432 ASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLT 1491
AS+I LN LNE LVTMP+GYVTHGLNLEEAAR MRSLK PA VSVSSPDAVT YNGYLT
Sbjct 1414 ASIITKLNLLNEPLVTMPIGYVTHGLNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLT 1473
Query 1492 SSSKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEV 1550
SSSKT EEHFIET+SLAG Y+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGEV
Sbjct 1474 SSSKTSEEHFIETVSLAGMYRDWSYSGQRTELGVEFLKRGDKVVYHTVGSPIQFHLDGEV 1533
Query 1551 ITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPH 1610
+ D LK+LLSLREVRTIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH
Sbjct 1534 LLLDKLKSLLSLREVRTIKVFTTVDNTNLHTQIVDMSMTYGQQFGPTYLDGADVTKIKPH 1593
Query 1611 NSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWA 1670
HEGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQ+ GLTSIKWA
Sbjct 1594 AKHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQIGGLTSIKWA 1653
Query 1671 DNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRE 1730
DNNCYL++ LL LQQIE+KFN PALQ+AYYRARAG+AANFCALILAY N+TVGELGDVRE
Sbjct 1654 DNNCYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAYSNRTVGELGDVRE 1713
Query 1731 TMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCG 1790
TM++L QHANL+S KRVLNVVCKTCGQ+ TTL GVEAVMYMGTLSYE+ K GV IPC CG
Sbjct 1714 TMTHLLQHANLESAKRVLNVVCKTCGQKSTTLTGVEAVMYMGTLSYEELKTGVTIPCICG 1773
Query 1791 KQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDG 1850
+ AT+YLVQQES FVMMSAPP++Y L+ G F CA+EYTG+YQCGHY H+T KETLY IDG
Sbjct 1774 RDATQYLVQQESSFVMMSAPPSEYTLQQGAFLCANEYTGSYQCGHYTHVTVKETLYRIDG 1833
Query 1851 ALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQ 1910
A LTK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV+ TEI PKLD YYKKDN+Y+TEQ
Sbjct 1834 AYLTKMSEYKGPVTDVFYKEISYTTTIKPVSYKLDGVIYTEIQPKLDEYYKKDNAYYTEQ 1893
Query 1911 PIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAI 1970
PIDLVP QP PNASFDNFK C N KFADDLNQ+TG+KKPASREL VTFFPDLNGDVVAI
Sbjct 1894 PIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFKKPASRELSVTFFPDLNGDVVAI 1953
Query 1971 DYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKS 2030
DY+HY+ SFKKGAKLLHKPI+WH+N TNK TYKPNTWC+RCLWSTKPVETSNSF+VL+
Sbjct 1954 DYRHYSASFKKGAKLLHKPIIWHINQTTNKTTYKPNTWCLRCLWSTKPVETSNSFEVLEV 2013
Query 2031 EDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEV 2090
ED QGMDNLACE P SEEVVENPTIQK+V+EC+VKT EVVG++ILKP+ +K+T+E+
Sbjct 2014 EDTQGMDNLACESQTPTSEEVVENPTIQKEVIECDVKTIEVVGNVILKPSEEGVKVTQEL 2073
Query 2091 GHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVV 2150
GH DLMAAYV+ +S+TIKKPNELS LGL+TLATHG AA+NSVPW I Y KPFL +
Sbjct 2074 GHEDLMAAYVEETSITIKKPNELSLALGLRTLATHGAAAINSVPWSKILAYVKPFLGQAA 2133
Query 2151 STTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFC 2210
TTTN + RC+ RV NYMPY TLL QLCTFTRSTNSRI+AS+PTTIAKN+VKSV K C
Sbjct 2134 VTTTNCIKRCVQRVFNNYMPYVITLLFQLCTFTRSTNSRIRASLPTTIAKNSVKSVAKLC 2193
Query 2211 LEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGY 2270
L+ NY+KSP FSKL I +W LLLS+CLGSLIY TAA GVL+SNLG+PSYC G RE Y
Sbjct 2194 LDVCINYVKSPKFSKLFTIAMWLLLLSICLGSLIYVTAAFGVLLSNLGIPSYCDGVRESY 2253
Query 2271 LNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLA 2330
+NS+NVT +C GS CSVCL+GLDSLD+YP+LETIQ+TISS+K DLT+ GL AEWFLA
Sbjct 2254 VNSSNVTTMDFCEGSFLCSVCLNGLDSLDSYPALETIQVTISSYKLDLTSLGLAAEWFLA 2313
Query 2331 YILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASF 2390
Y+LFT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFA
Sbjct 2314 YMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFAFC 2373
Query 2391 YYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNW 2450
YYVWKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNW
Sbjct 2374 YYVWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKAHNW 2433
Query 2451 NCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQ 2510
NC+NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSY+VDSV VKNG++HLYFDKAGQ
Sbjct 2434 NCLNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAGQ 2493
Query 2511 KTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPIL 2570
KTYERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES+AKSASVYYSQLMCQPIL
Sbjct 2494 KTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPIL 2553
Query 2571 LLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVL 2630
LLDQALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VL
Sbjct 2554 LLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVL 2613
Query 2631 STFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGA 2690
STF+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGA
Sbjct 2614 STFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGA 2673
Query 2691 CIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQV 2750
CIDC+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQV
Sbjct 2674 CIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQV 2733
Query 2751 VNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYK 2810
VN +TTKI+LKGGKIV+ W K ++K TL+ + A Y+I PVH +S H +++EIIGYK
Sbjct 2734 VNAITTKISLKGGKIVSTWFKLMLKATLLCVLAALFCYIIMPVHSLSVHDGYTNEIIGYK 2793
Query 2811 AIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLP 2870
AI GVTRDI +TD CFANKHA FD+WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLP
Sbjct 2794 AIQDGVTRDIMATDDCFANKHAGFDSWFSQRGGSYRNDKSCPVVAAIITREIGFIVPGLP 2853
Query 2871 GTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPV 2930
GT+LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPV
Sbjct 2854 GTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPV 2913
Query 2931 PYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCE 2990
PYCYDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCE
Sbjct 2914 PYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCE 2973
Query 2991 RSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAG 3050
RSEAGVC+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAG
Sbjct 2974 RSEAGVCLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAG 3033
Query 3051 GIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYL 3110
GI+AI+VTC AYYFM+FRRAFGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYS+ YL
Sbjct 3034 GIIAILVTCAAYYFMKFRRAFGEYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFYL 3093
Query 3111 YLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGV 3170
YLTFY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNGV
Sbjct 3094 YLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGV 3153
Query 3171 SFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAA 3230
+FSTFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAA
Sbjct 3154 TFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAA 3213
Query 3231 CCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTL 3290
CCHLAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTL
Sbjct 3214 CCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTL 3273
Query 3291 NGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVL 3350
NGLWLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L
Sbjct 3274 NGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLL 3333
Query 3351 KLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGS 3410
+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN+TIKGSFLNGSCGS
Sbjct 3334 RLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNYTIKGSFLNGSCGS 3393
Query 3411 VGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAW 3470
VGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAW
Sbjct 3394 VGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAW 3453
Query 3471 LYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAS 3530
LYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+
Sbjct 3454 LYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAA 3513
Query 3531 LKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTS 3590
LKELLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTS
Sbjct 3514 LKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTS 3573
Query 3591 LLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYF 3650
LL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYF
Sbjct 3574 LLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYF 3633
Query 3651 NMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWT 3710
NMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL+LMTARTVYDD ARRVWT
Sbjct 3634 NMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVWT 3693
Query 3711 LMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFF 3770
LMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ F
Sbjct 3694 LMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLF 3753
Query 3771 ITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLP 3830
ITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLP
Sbjct 3754 ITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLP 3813
Query 3831 PKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQ 3890
PK+SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQ
Sbjct 3814 PKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQ 3873
Query 3891 CVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSS 3950
CVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSS
Sbjct 3874 CVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSS 3933
Query 3951 LPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMT 4010
LPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMT
Sbjct 3934 LPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMT 3993
Query 4011 QMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKL 4070
QMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKL
Sbjct 3994 QMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKL 4053
Query 4071 MVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTA 4130
MVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNS NLAWPLIVTA
Sbjct 4054 MVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSQNLAWPLIVTA 4113
Query 4131 LRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQD 4190
LRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QD
Sbjct 4114 LRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQD 4173
Query 4191 LKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATV 4250
LKWARFPKSDGTGTIYTELEPPCRFVTDTP+GPKVKYLYFIKGLNNLNRGMVLGSLAATV
Sbjct 4174 LKWARFPKSDGTGTIYTELEPPCRFVTDTPRGPKVKYLYFIKGLNNLNRGMVLGSLAATV 4233
Query 4251 RLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITV 4310
RLQAGNATEVPANS VLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITV
Sbjct 4234 RLQAGNATEVPANSAVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITV 4293
Query 4311 TPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVC 4370
TPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIP TCANDPVGFTLKNTVC
Sbjct 4294 TPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPATCANDPVGFTLKNTVC 4353
Query 4371 TVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIY 4430
TVCG WKGYGCSCDQLREPM+QSADA +FLNRVCGVSAARLTPCGTGTSTDVVYRAFDIY
Sbjct 4354 TVCGTWKGYGCSCDQLREPMMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIY 4413
Query 4431 NDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAK 4490
N++VAGFAKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+K+CPAVA
Sbjct 4414 NERVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKECPAVAV 4473
Query 4491 HDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFN 4550
HDFFKFR+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFN
Sbjct 4474 HDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFN 4533
Query 4551 KKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYD 4610
KKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWYD
Sbjct 4534 KKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYD 4593
Query 4611 FGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEE 4670
FGDF+Q PG GVP+VDSYYSLLMPILTLT+AL AESH+D DL KP IKWDLLKYDFTEE
Sbjct 4594 FGDFVQVAPGCGVPIVDSYYSLLMPILTLTKALAAESHMDADLAKPLIKWDLLKYDFTEE 4653
Query 4671 RLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGV 4730
RL LFDRYFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGV
Sbjct 4654 RLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGV 4713
Query 4731 PFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSV 4790
PFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSV
Sbjct 4714 PFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSV 4773
Query 4791 AALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRY 4850
AALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRY
Sbjct 4774 AALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRY 4833
Query 4851 NLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDS 4910
NLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDS
Sbjct 4834 NLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDS 4893
Query 4911 MSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKS 4970
MSYEDQD LFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKS
Sbjct 4894 MSYEDQDVLFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKS 4953
Query 4971 IAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVL 5030
IAATRGATVVIGTSKFYGGWHNMLKTVYSDVE PHLMGWDYPKCDRAMPNMLRIMASLVL
Sbjct 4954 IAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVL 5013
Query 5031 ARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQ 5090
ARKH+TCC+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQ
Sbjct 5014 ARKHSTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQ 5073
Query 5091 AVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMIL 5150
AVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV+EFYAYLRKHFSMMIL
Sbjct 5074 AVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMIL 5133
Query 5151 SDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTM 5210
SDDAVVC+NS YA+QGLVASIKNFK+V YYQNNVFMSEAKCWTETDLTKGPHEFCSQHTM
Sbjct 5134 SDDAVVCYNSNYAAQGLVASIKNFKAVHYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTM 5193
Query 5211 LVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYA 5270
LVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYA
Sbjct 5194 LVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYA 5253
Query 5271 DVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACV 5330
DVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACV
Sbjct 5254 DVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACV 5313
Query 5331 LCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLG 5390
LCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLG
Sbjct 5314 LCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLG 5373
Query 5391 GMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTC 5450
GMSYYCK HKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTC
Sbjct 5374 GMSYYCKLHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTC 5433
Query 5451 TERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYR 5510
TERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYR
Sbjct 5434 TERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYR 5493
Query 5511 VTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY 5570
VTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY
Sbjct 5494 VTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY 5553
Query 5571 VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVY 5630
VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVY
Sbjct 5554 VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVY 5613
Query 5631 TACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPET 5690
TACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPET
Sbjct 5614 TACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPET 5673
Query 5691 TADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC 5750
TADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC
Sbjct 5674 TADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC 5733
Query 5751 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSS 5810
RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHK+KSAQCFKMFYKGVITHDVSS
Sbjct 5734 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKEKSAQCFKMFYKGVITHDVSS 5793
Query 5811 AINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIF 5870
AINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIF
Sbjct 5794 AINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIF 5853
Query 5871 TQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVT 5930
TQTTETAHSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLE+PRRNVATLQAENVT
Sbjct 5854 TQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEVPRRNVATLQAENVT 5913
Query 5931 GLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQ 5990
GLFKDCSK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQ
Sbjct 5914 GLFKDCSKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQ 5973
Query 5991 VNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYV 6050
VNGYPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAVPTGYV
Sbjct 5974 VNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYV 6033
Query 6051 DTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVL 6110
DT NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFVL
Sbjct 6034 DTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVL 6093
Query 6111 WAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQ 6170
WAHGFELTSMKYFVKIGPERTCCLCDRRATCFST+SDTYACW+HS+GFDYVYNPFMIDVQ
Sbjct 6094 WAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQ 6153
Query 6171 QWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKI 6230
QWGFTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDELKI
Sbjct 6154 QWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELKI 6213
Query 6231 NAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEE 6290
NAACRKVQHMVVK+ALLADKF VLHDIGNPKAIKCVPQA+V+WKFYDAQPCSDKAYKIEE
Sbjct 6214 NAACRKVQHMVVKSALLADKFSVLHDIGNPKAIKCVPQAEVDWKFYDAQPCSDKAYKIEE 6273
Query 6291 LFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHA 6350
LFYSYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKHA
Sbjct 6274 LFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHA 6333
Query 6351 FHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCR 6410
FHTPAFDKSAF LKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCR
Sbjct 6334 FHTPAFDKSAFTYLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCR 6393
Query 6411 HHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQ 6470
HANEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQSLENVA+NVVNKGHFDGQ
Sbjct 6394 RHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGQ 6453
Query 6471 QGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVD 6530
GE PVSIINN VYTKVDG DVE+FENKTTLPVNVAFELWAKRNIKPVPE+KILNNLGVD
Sbjct 6454 IGEAPVSIINNAVYTKVDGNDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVD 6513
Query 6531 IAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNAR 6590
IAANTVIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ LTV FDGRV+GQVDLFRNAR
Sbjct 6514 IAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNAR 6573
Query 6591 NGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSR 6650
NGVLITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQSR
Sbjct 6574 NGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSR 6633
Query 6651 NLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRF 6710
+L++FKPRS+ME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR
Sbjct 6634 DLEDFKPRSKMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRS 6693
Query 6711 KESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVV 6770
++SP +LEDFIP DSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV+SKVV
Sbjct 6694 QDSPLKLEDFIPTDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVV 6753
Query 6771 KVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGD 6830
KVTIDY EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG+
Sbjct 6754 KVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGE 6813
Query 6831 SATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTG 6890
+A +PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTG
Sbjct 6814 NAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTG 6873
Query 6891 TLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTY 6950
LLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTK+VTKENDSKEGFFTY
Sbjct 6874 ALLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKHVTKENDSKEGFFTY 6933
Query 6951 ICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYL 7010
+CGFI+QKLALGGSVA+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NYL
Sbjct 6934 LCGFIKQKLALGGSVAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGVNYL 6993
Query 7011 GKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMIL 7070
GK REQIDGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI
Sbjct 6994 GKLREQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIY 7053
Query 7071 SLLSKGRLIIRENNRVVISSDVLVNN 7096
SLL GRLIIRENNRVV+SSD+LVNN
Sbjct 7054 SLLENGRLIIRENNRVVVSSDILVNN 7079
>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071
Score = 10325 bits (26794), Expect = 0.0, Method: Composition-based stats.
Identities = 6088/7100 (86%), Positives = 6573/7100 (93%), Gaps = 33/7100 (0%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK GTCG+VE+EKGV
Sbjct 1 MESLVLGINEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKSGTCGIVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQ EQPYVFIKRSDA+ HGH + ELVAEL+G+QYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQPEQPYVFIKRSDAQGTDHGHRVRELVAELDGVQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHS+G DLKS+DLGDELGTDP ED+++NWNTKH SGV REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGVLRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A TRYVDNNFCGPDGYPLECIKDLLARAGK+ CTLSEQLD+I++KRGVYCCR+H HEIAW
Sbjct 181 ALTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCRDHGHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TCGYL
Sbjct 301 RSVYPVATPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVSEGPNTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + E+GPEHS A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSAADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF+LNEE+AIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFQLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+ +S+L+PL F S+A
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPIKGAWNIGQHRSVLTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIFSRTL+ A +S+ LQ+AA+TILD IS+ SLRL+DAM++TS+L TN++++MAY
Sbjct 541 AGVIRSIFSRTLDAANHSIPDLQRAAVTILDSISEQSLRLVDAMVYTSNLLTNSVIIMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ TSQWL+N+ T EKL+P+ W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 VTGGLVQQTSQWLSNLLDTTVEKLRPIFAWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNIKDCVKCFVDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAVVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVCINGLMLLEIK E+YCAL+P ++ TNN F LKGGAPTK VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCINGLMLLEIKANEQYCALSPGLLATNNVFRLKGGAPTKGVTFGEDTVVEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEP--STQYEYGTEDDYQG 957
WS+AT+YLFD+SGE KL+S MYCSFYPPDE+E+ + EEEE + ++EYGTE+DY+G
Sbjct 901 WSVATFYLFDDSGEEKLSSRMYCSFYPPDEEEDCEEYEEEEEVSERTCEHEYGTEEDYKG 960
Query 958 KPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELT 1017
PLEFGA++ +Q EE++EEDWLDD
Sbjct 961 LPLEFGASTDIIQVEEQEEEDWLDD---------------------------AVEAEPEP 993
Query 1018 PVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
+ VN +GYLKLTDNV IK DIVEEA+ P V+VNAAN++LKHGGGVAGALNK
Sbjct 994 EPLHEEPVNQLTGYLKLTDNVAIKCVDIVEEAQNANPMVIVNAANIHLKHGGGVAGALNK 1053
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
ATN AMQ ESD YI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYEN
Sbjct 1054 ATNGAMQKESDHYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYEN 1113
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK 1197
FN ++LLAPLLSAGIFGA P+ SL++CV TVRT VY+ V DK LY+++V +L+ K
Sbjct 1114 FNSQDILLAPLLSAGIFGAKPLQSLQMCVQTVRTQVYIVVNDKVLYEQVVMDYLDSLKPK 1173
Query 1198 QVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYI 1257
K +PK E + K V++ KIKAC++EVTTTLEETKFLT LLL+
Sbjct 1174 VEAPKQEVLPKAEYPK--VDEKSVVQKTIDVKPKIKACIDEVTTTLEETKFLTNKLLLFT 1231
Query 1258 DINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKAL 1317
DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML++AL
Sbjct 1232 DINGKLYQDSKNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLSRAL 1291
Query 1318 RKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLRE 1377
+KVP + YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSWNLRE
Sbjct 1292 KKVPINEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSETPNAKEEILGTVSWNLRE 1351
Query 1378 MLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINT 1437
MLAHAEETRKLMPVC++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS+I
Sbjct 1352 MLAHAEETRKLMPVCMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITK 1411
Query 1438 LNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTP 1497
LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSSSKT
Sbjct 1412 LNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAIVSVSSPDAVTTYNGYLTSSSKTS 1471
Query 1498 EEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVITFDNL 1556
E+HF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRG+K VY+T +P FHLDGEV+ D L
Sbjct 1472 EDHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGEKIVYHTLESPVKFHLDGEVLPLDKL 1531
Query 1557 KTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGK 1616
K+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQ GPTYL+GADVTKIKPH +HEGK
Sbjct 1532 KSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQLGPTYLEGADVTKIKPHVNHEGK 1591
Query 1617 TFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYL 1676
TF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNNCYL
Sbjct 1592 TFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYL 1651
Query 1677 ATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLF 1736
++ LL LQQIE+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM++L
Sbjct 1652 SSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLL 1711
Query 1737 QHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKY 1796
QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+ AT+Y
Sbjct 1712 QHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKMGVSIPCVCGRDATQY 1771
Query 1797 LVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKS 1856
LVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA LTK
Sbjct 1772 LVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKM 1831
Query 1857 SEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVP 1916
SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPIDL+P
Sbjct 1832 SEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLIP 1891
Query 1917 NQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYT 1976
QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY+HY+
Sbjct 1892 TQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYS 1951
Query 1977 PSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGM 2036
SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED QGM
Sbjct 1952 ASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGM 2011
Query 2037 DNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLM 2096
DNLACE +P EEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+ H DLM
Sbjct 2012 DNLACESQQPTPEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELDHEDLM 2071
Query 2097 AAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNI 2156
AAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + TT+N
Sbjct 2072 AAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWGKILAYVKPFLGQAAVTTSNC 2131
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
R + R+ NYMPY TLL QLCTFT+STNSRI+AS+PTTIAKN+V+ + + CL+A N
Sbjct 2132 AKRLVQRMFNNYMPYVLTLLFQLCTFTKSTNSRIRASLPTTIAKNSVRGIVRLCLDAGIN 2191
Query 2217 YLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNV 2276
Y+KSP FSKL I +W LLLS+CLGSLIY TAALGVL+SN G PSYC+G RE YLNS+NV
Sbjct 2192 YVKSPKFSKLFTIAMWLLLLSICLGSLIYVTAALGVLLSNFGAPSYCSGVRESYLNSSNV 2251
Query 2277 TIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTR 2336
T +C GS PCSVCLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEWF AY+LFT+
Sbjct 2252 TTMDFCEGSFPCSVCLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWFFAYMLFTK 2311
Query 2337 FFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKS 2396
FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY+WKS
Sbjct 2312 FFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKS 2371
Query 2397 YVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCD 2456
YVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC+NCD
Sbjct 2372 YVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCD 2431
Query 2457 TFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERH 2516
TFCAGSTFISDEVARDLSLQFKRPINPTDQSSY+VDSV VKNG++HLYFDKAGQKTYERH
Sbjct 2432 TFCAGSTFISDEVARDLSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAGQKTYERH 2491
Query 2517 SLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQAL 2576
LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES+AKSASVYYSQLMCQPILLLDQAL
Sbjct 2492 PLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPILLLDQAL 2551
Query 2577 VSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISA 2636
VSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF+SA
Sbjct 2552 VSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSA 2611
Query 2637 ARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSA 2696
+RQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACIDC+A
Sbjct 2612 SRQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNA 2671
Query 2697 RHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTT 2756
RHINAQVA+SHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV+TT
Sbjct 2672 RHINAQVARSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITT 2731
Query 2757 KIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGV 2816
KI+LKGGKIV+ W K ++K TL+ + A + Y++ PVH++S H +++EIIGYKAI GV
Sbjct 2732 KISLKGGKIVSTWFKIMLKATLLCVLAALVCYIVMPVHILSVHGGYTNEIIGYKAIQDGV 2791
Query 2817 TRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRT 2876
TRDI STD CFANKHA FD+WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT+LR
Sbjct 2792 TRDIVSTDDCFANKHAGFDSWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRA 2851
Query 2877 TNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDT 2936
NGDFLHFLPRVFSAVGNICYTPSKLIEY+DF+TSACVLAAECTIFKDA GKPVPYCYDT
Sbjct 2852 INGDFLHFLPRVFSAVGNICYTPSKLIEYSDFSTSACVLAAECTIFKDAMGKPVPYCYDT 2911
Query 2937 NVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGV 2996
N+LEGS++Y LRPDTRYVLMDGSIIQFPN YLEGSVRVVTTFD+EYCRHGTCERSEAG+
Sbjct 2912 NLLEGSISYSELRPDTRYVLMDGSIIQFPNAYLEGSVRVVTTFDAEYCRHGTCERSEAGI 2971
Query 2997 CVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIV 3056
C+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+AI+
Sbjct 2972 CLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAIL 3031
Query 3057 VTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYL 3116
VTC AYYFM+FRRAFGEY+HVVA N LFLMSFT+LCL P YSFLPGVYSV YLYLTFY
Sbjct 3032 VTCAAYYFMKFRRAFGEYNHVVAANAPLFLMSFTILCLAPAYSFLPGVYSVFYLYLTFYF 3091
Query 3117 TNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE 3176
TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KHF+WFF+NYL++RVVFNGV+FSTFE
Sbjct 3092 TNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHFHWFFNNYLRKRVVFNGVTFSTFE 3151
Query 3177 EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAK 3236
EAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCHLAK
Sbjct 3152 EAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAK 3211
Query 3237 ALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLD 3296
ALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLD
Sbjct 3212 ALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLD 3271
Query 3297 DVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDT 3356
D VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT
Sbjct 3272 DTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDT 3331
Query 3357 ANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNID 3416
+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGFNID
Sbjct 3332 SNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNID 3391
Query 3417 YDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVI 3476
YDCVSFCYMHHMELPT VHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVI
Sbjct 3392 YDCVSFCYMHHMELPTEVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVI 3451
Query 3477 NGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQ 3536
NGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQ
Sbjct 3452 NGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQ 3511
Query 3537 NGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQ 3596
NGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ KR +KGTHHW+LLT LTSLL+LVQ
Sbjct 3512 NGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKRIVKGTHHWMLLTFLTSLLILVQ 3571
Query 3597 STQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP 3656
STQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMVYMP
Sbjct 3572 STQWSLFFFVYENAFLPFTLGIMAVAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMP 3631
Query 3657 ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLT 3716
ASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL+LMTARTVYDD ARRVWTLMNV+T
Sbjct 3632 ASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVWTLMNVIT 3691
Query 3717 LVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTL 3776
LVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITGNTL
Sbjct 3692 LVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTL 3751
Query 3777 QCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSID 3836
QCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+SID
Sbjct 3752 QCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSID 3811
Query 3837 AFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHN 3896
AFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHN
Sbjct 3812 AFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHN 3871
Query 3897 DILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA 3956
DILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA
Sbjct 3872 DILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA 3931
Query 3957 FATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQA 4016
+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR+AAMQRKLEKMADQAMTQMYKQA
Sbjct 3932 YATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRNAAMQRKLEKMADQAMTQMYKQA 3991
Query 4017 RSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPD 4076
RSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV+PD
Sbjct 3992 RSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPD 4051
Query 4077 YNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSA 4136
Y TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+M+NS NLAWPLIVTALRANSA
Sbjct 4052 YGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMENSSNLAWPLIVTALRANSA 4111
Query 4137 VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARF 4196
VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLKWARF
Sbjct 4112 VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARF 4171
Query 4197 PKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGN 4256
PKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL+FIKGLNNLNRGMVLGSLAATVRLQAGN
Sbjct 4172 PKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLHFIKGLNNLNRGMVLGSLAATVRLQAGN 4231
Query 4257 ATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANM 4316
ATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANM
Sbjct 4232 ATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANM 4291
Query 4317 DQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMW 4376
DQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVCGMW
Sbjct 4292 DQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMW 4351
Query 4377 KGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAG 4436
KGYGCSCDQLREPM+QSADA +FLNRVCGVSAARLTPCGTG STDVVYRAFDIYN+KVAG
Sbjct 4352 KGYGCSCDQLREPMMQSADASTFLNRVCGVSAARLTPCGTGISTDVVYRAFDIYNEKVAG 4411
Query 4437 FAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKF 4496
FAKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+KDCPAVA HDFFKF
Sbjct 4412 FAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKF 4471
Query 4497 RIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYD 4556
R+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYD
Sbjct 4472 RVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYD 4531
Query 4557 FVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQ 4616
FVENPDILRVYANLGERVRQALLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWYDFGDF+Q
Sbjct 4532 FVENPDILRVYANLGERVRQALLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQ 4591
Query 4617 TTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFD 4676
PG GVP+VDSYYSLLMPILTLTRAL AESH+D DL KP IKWDLLKYDFT ERL LFD
Sbjct 4592 VAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTAERLCLFD 4651
Query 4677 RYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVST 4736
RYFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVST
Sbjct 4652 RYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVST 4711
Query 4737 GYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNN 4796
GYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNN
Sbjct 4712 GYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNN 4771
Query 4797 VAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMC 4856
VAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMC
Sbjct 4772 VAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMC 4831
Query 4857 DIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQ 4916
DIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQ
Sbjct 4832 DIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQ 4891
Query 4917 DALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRG 4976
DALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRG
Sbjct 4892 DALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRG 4951
Query 4977 ATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTT 5036
ATVVIGTSKFYGGWHNMLKTVYSDVE PHLMGWDYPKCDRAMPNMLRIMASLVLARKH+T
Sbjct 4952 ATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHST 5011
Query 5037 CCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANV 5096
CC+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANV
Sbjct 5012 CCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANV 5071
Query 5097 NALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVV 5156
NALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV EFYAYLRKHFSMMILSDDAVV
Sbjct 5072 NALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVGEFYAYLRKHFSMMILSDDAVV 5131
Query 5157 CFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGD 5216
C+NS YA+QGLVASIKNFK+VLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGD
Sbjct 5132 CYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGD 5191
Query 5217 DYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLY 5276
DYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLY
Sbjct 5192 DYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLY 5251
Query 5277 LQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQT 5336
LQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQT
Sbjct 5252 LQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQT 5311
Query 5337 SLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYC 5396
SLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYC
Sbjct 5312 SLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYC 5371
Query 5397 KSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKL 5456
KSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKL
Sbjct 5372 KSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKL 5431
Query 5457 FAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSK 5516
FAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSK
Sbjct 5432 FAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSK 5491
Query 5517 VQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGL 5576
VQIGEYTFEKGDYGDAVVYRGTTTYKLN+GDYFVLTSHTVMPLSAPTLVPQEHYVRITGL
Sbjct 5492 VQIGEYTFEKGDYGDAVVYRGTTTYKLNIGDYFVLTSHTVMPLSAPTLVPQEHYVRITGL 5551
Query 5577 YPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHA 5636
YPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHA
Sbjct 5552 YPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHA 5611
Query 5637 AVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVV 5696
AVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVV
Sbjct 5612 AVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVV 5671
Query 5697 FDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTI 5756
FDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTI
Sbjct 5672 FDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTI 5731
Query 5757 GPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQ 5816
GPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHK+KSAQCFKMFYKGVITHDVSSAINRPQ
Sbjct 5732 GPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKEKSAQCFKMFYKGVITHDVSSAINRPQ 5791
Query 5817 IGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTET 5876
IGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTET
Sbjct 5792 IGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTET 5851
Query 5877 AHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDC 5936
AHSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLE+PRRNVATLQAENVTGLFKDC
Sbjct 5852 AHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEVPRRNVATLQAENVTGLFKDC 5911
Query 5937 SKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPN 5996
SK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPN
Sbjct 5912 SKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPN 5971
Query 5997 MFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNT 6056
MFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVA+PTGYVDT NNT
Sbjct 5972 MFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAIPTGYVDTENNT 6031
Query 6057 DFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFE 6116
+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFVLWAHGFE
Sbjct 6032 EFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFE 6091
Query 6117 LTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTG 6176
LTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPFMIDVQQWGFTG
Sbjct 6092 LTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTG 6151
Query 6177 NLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRK 6236
NLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDELKIN+ACRK
Sbjct 6152 NLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELKINSACRK 6211
Query 6237 VQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYA 6296
VQHMVVK+ALLADKFPVLHDIGNPKAIKCVPQA+VEWKFYDAQPCSDKAYKIEELFYSYA
Sbjct 6212 VQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYA 6271
Query 6297 THSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAF 6356
TH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAF
Sbjct 6272 THHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAF 6331
Query 6357 DKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEY 6416
DKSAF NLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEY
Sbjct 6332 DKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEY 6391
Query 6417 RLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPV 6476
R YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQSLENVA+NVVNKGHFDGQ GE PV
Sbjct 6392 RQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGQAGETPV 6451
Query 6477 SIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTV 6536
SIINN VYTKVDG DVE+FENKTTLPVNVAFELWAKRNIK VPE+KILNNLGVDIAANTV
Sbjct 6452 SIINNAVYTKVDGFDVEIFENKTTLPVNVAFELWAKRNIKSVPEIKILNNLGVDIAANTV 6511
Query 6537 IWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLIT 6596
IWD+KR+AP H+STIGVC+MTDIAKKPTE+ C+ LTV FDGRV+GQVDLFRNARNGVLIT
Sbjct 6512 IWDHKREAPVHMSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLIT 6571
Query 6597 EGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFK 6656
EGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQSR+L++FK
Sbjct 6572 EGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFK 6631
Query 6657 PRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFE 6716
PRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR ++SP +
Sbjct 6632 PRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSRDSPLK 6691
Query 6717 LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDY 6776
LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDY
Sbjct 6692 LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDY 6751
Query 6777 TEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPK 6836
EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG++A +PK
Sbjct 6752 AEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPK 6811
Query 6837 GIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDS 6896
GIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDS
Sbjct 6812 GIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDS 6871
Query 6897 DLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQ 6956
DLNDFVSDADSTLIGDCATVHTANKWDLI+SDMYDPK K+VTKENDSKEGFFTY+CGFI+
Sbjct 6872 DLNDFVSDADSTLIGDCATVHTANKWDLIVSDMYDPKAKHVTKENDSKEGFFTYLCGFIK 6931
Query 6957 QKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQ 7016
QKLALGGSVA+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NYLGKP+EQ
Sbjct 6932 QKLALGGSVAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGVNYLGKPKEQ 6991
Query 7017 IDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKG 7076
IDGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI SLL KG
Sbjct 6992 IDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKG 7051
Query 7077 RLIIRENNRVVISSDVLVNN 7096
RLIIRENNRVV+SSD+LVNN
Sbjct 7052 RLIIRENNRVVVSSDILVNN 7071
>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067
Score = 10322 bits (26785), Expect = 0.0, Method: Composition-based stats.
Identities = 6092/7099 (86%), Positives = 6572/7099 (93%), Gaps = 35/7099 (0%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA + HGH +VELVAEL+GIQ+GRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAELDGIQFGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHS+G DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
TRYVDNNFCGPDGYPLECIKD LARAGK+ CTLSEQLD+I++KRGVYCCREHEHEI W
Sbjct 181 VVTRYVDNNFCGPDGYPLECIKDFLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERSEKSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSEKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + EVGPEHS+A+YHN S ++T LRKGGRT FGGCVFSYVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFSYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIG NHTG+ GE E LN++LLEIL +E+VNINIVGDF+ NEE+AIILASF
Sbjct 421 AYWVPRASANIGANHTGITGENVETLNEDLLEILNRERVNINIVGDFRFNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SAS SAF+ETVKGLDYK+FK IVESCGN+KVT GK GAWNIG+Q+SIL+PL F S+A
Sbjct 481 SASPSAFIETVKGLDYKSFKVIVESCGNYKVTNGKPVTGAWNIGQQRSILTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIFSRTL+ A +S+ LQ+AA+T LDGIS+ SLRL+DAM++TSDL TN++VVMAY
Sbjct 541 AGVIRSIFSRTLDAANHSILDLQRAAVTTLDGISEQSLRLVDAMVYTSDLLTNSVVVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ T QWL+N+ GT +KLKPV W+E K GVEFLRD WEI+KF+ T +++
Sbjct 601 VTGGLVQQTMQWLSNMLGTAVDKLKPVFTWVEAKLSAGVEFLRDAWEILKFLITGVFDVI 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI IKE V+ F +VNK L +C D + I G KL+ALNLGE F+ S+GLYR+C
Sbjct 661 KGQIQVATDNIKECVKIFLGVVNKALEMCLDQVTIAGTKLRALNLGEVFIAQSRGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG+ T + +EEVVLK+G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDAHDTVLTSEEVVLKSGELEALETPIDSFTSGAVVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVCINGLMLLE+++ E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCINGLMLLELENKEQYCALSPGLLATNNVFRLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELD R+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLTP+GIDLDE
Sbjct 841 KITFELDVRVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTPMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKP 959
WS+AT+YLFD++GE KL+S MYCSFYPPD EEE E E+ E + ++EYGTEDDY+G P
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPD--EEEDCEECEDEEETCEHEYGTEDDYKGLP 958
Query 960 LEFGATSAALQPEEEQEE-DWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
LEFGA++ EEE+EE DWLDD + +
Sbjct 959 LEFGASTETPHVEEEEEEEDWLDDAIEAEPEPE--------------------------- 991
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
+ VN F GYLKLTDNV IK DIV+EA+ KPTV+VNAAN +LKHGGGVAGALNKA
Sbjct 992 PLPEEPVNQFVGYLKLTDNVAIKCIDIVKEAQSAKPTVIVNAANTHLKHGGGVAGALNKA 1051
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
TN AMQ ESD+YI NGPL VGGSC+LSGHNLA+ CLHVVGPN+N GED+QLLK AYENF
Sbjct 1052 TNGAMQNESDEYIRQNGPLTVGGSCLLSGHNLAEKCLHVVGPNLNAGEDVQLLKRAYENF 1111
Query 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
N +VLLAPLLSAGIFGA P+ SL++CV+ VRT VYLAV DK+LYD++V +L+ K
Sbjct 1112 NSQDVLLAPLLSAGIFGAKPLQSLKMCVEIVRTQVYLAVNDKSLYDQIVLDYLDSLKPKV 1171
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYID 1258
E PK E + +P E+ KIKAC++EVTTTLEETKFLT LLL+ D
Sbjct 1172 ESPNKEEEPKLEEPKAV---QPVAEKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFAD 1228
Query 1259 INGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALR 1318
ING L+ DS ++ D++FL+KDAPYIVGDV+ G +T V+IP KK+GGTTEMLA+AL+
Sbjct 1229 INGKLYQDSQNMLRGEDMSFLEKDAPYIVGDVITSGDITCVIIPAKKSGGTTEMLARALK 1288
Query 1319 KVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREM 1378
+VP YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS NEK+E+LGTVSWNLREM
Sbjct 1289 EVPVAEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSETPNEKEEVLGTVSWNLREM 1348
Query 1379 LAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTL 1438
LAHAEETRKLMP+C++ +AI++TIQRKYKGIK+QEG+VDYG RF+FYTSK VAS+I L
Sbjct 1349 LAHAEETRKLMPICLDVRAIMATIQRKYKGIKVQEGIVDYGVRFFFYTSKEPVASIITKL 1408
Query 1439 NDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPE 1498
N LNE LVTMP+GYVTHGLNLEEAAR MRSLK PA VSVSSPDAVTAYNGYLTSSSKTPE
Sbjct 1409 NSLNEPLVTMPIGYVTHGLNLEEAARCMRSLKAPAVVSVSSPDAVTAYNGYLTSSSKTPE 1468
Query 1499 EHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTS-NPTTFHLDGEVITFDNLK 1557
E+F+ET SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T+ +P FHLDGEV+ D LK
Sbjct 1469 EYFVETTSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTTGSPIEFHLDGEVLPLDKLK 1528
Query 1558 TLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKT 1617
+LLSLREV+TIKVFTTVDN NLHT +VDMSMTYGQQFGPTYLDGADVTKIKPH +HEGKT
Sbjct 1529 SLLSLREVKTIKVFTTVDNTNLHTHIVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKT 1588
Query 1618 FYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLA 1677
F+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNNCYL+
Sbjct 1589 FFVLPSDDTLRSEAFEYYHTIDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLS 1648
Query 1678 TALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQ 1737
+ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM++L Q
Sbjct 1649 SVLLALQQVEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQ 1708
Query 1738 HANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYL 1797
HANL+S KRVLNVVCK CGQ+ TTLKGVEAVMYMGTLSY++ K GV IPC CG+ AT+YL
Sbjct 1709 HANLESAKRVLNVVCKHCGQKTTTLKGVEAVMYMGTLSYDELKTGVSIPCVCGRNATQYL 1768
Query 1798 VQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSS 1857
VQQES FVMMSAPPA+Y+L+ G F CA+EYTGNYQCGHY HIT+KETLY +DGA LTK S
Sbjct 1769 VQQESSFVMMSAPPAEYKLQQGAFLCANEYTGNYQCGHYTHITAKETLYRVDGAHLTKMS 1828
Query 1858 EYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPN 1917
EYKGP+TDVFYKE SYTT IKPV+YKLDGV TEI+PKLD YYKK N+Y+TEQPIDLVP
Sbjct 1829 EYKGPVTDVFYKETSYTTAIKPVSYKLDGVTYTEIEPKLDGYYKKGNAYYTEQPIDLVPT 1888
Query 1918 QPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTP 1977
QP PNASFDNFK C N KFADDLNQ+TG+KKPASREL VTFFPDLNGDVVAIDY+HY+
Sbjct 1889 QPMPNASFDNFKLTCSNTKFADDLNQMTGFKKPASRELTVTFFPDLNGDVVAIDYRHYST 1948
Query 1978 SFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMD 2037
SFKKGAKL+HKPI+WH+N TNK TYKPN WC+RCLWSTKPV+TSNSF+VL ED QGMD
Sbjct 1949 SFKKGAKLVHKPILWHINQTTNKTTYKPNIWCLRCLWSTKPVDTSNSFEVLVVEDTQGMD 2008
Query 2038 NLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMA 2097
NLACE SEEVVENPT+QK+++EC+VKTTEVVG++ILKP+ +K+T+E+GH DLMA
Sbjct 2009 NLACESQTTTSEEVVENPTVQKEIIECDVKTTEVVGNVILKPSEEGVKVTQELGHEDLMA 2068
Query 2098 AYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIV 2157
AYV+ +S+TIKKPNELS LGLKTLATHG AA+NSVPW I Y KPFL + T+N +
Sbjct 2069 AYVEETSITIKKPNELSLALGLKTLATHGAAAINSVPWSKILAYVKPFLGQTAVITSNCI 2128
Query 2158 TRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNY 2217
+C+ RV +NYMPY TLL QLCTFT+STNSRIKAS+PTTIAKN+VKSV K CL+ NY
Sbjct 2129 KKCVQRVFSNYMPYVITLLFQLCTFTKSTNSRIKASLPTTIAKNSVKSVAKLCLDVCINY 2188
Query 2218 LKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVT 2277
+KSP FSKL I++W LLLS+CLGSL Y TA LGV +S+LG+PSYC G RE Y+NS+NVT
Sbjct 2189 VKSPKFSKLFTIVMWLLLLSICLGSLTYVTAVLGVCLSSLGVPSYCDGVRELYINSSNVT 2248
Query 2278 IATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRF 2337
+C G PCSVCLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+LFT+F
Sbjct 2249 TMDFCQGYFPCSVCLSGLDSLDSYPALETIQVTISSYKLDLTFLGLAAEWLLAYMLFTKF 2308
Query 2338 FYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY 2397
FY+LGL+AIMQ FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYYVWKSY
Sbjct 2309 FYLLGLSAIMQAFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYVWKSY 2368
Query 2398 VHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDT 2457
VH++DGC SSTCMMCYKRNRATRVECTTIVNGV+RSFYVYANGG+GFCK HNWNC+NCDT
Sbjct 2369 VHIMDGCTSSTCMMCYKRNRATRVECTTIVNGVKRSFYVYANGGRGFCKAHNWNCLNCDT 2428
Query 2458 FCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHS 2517
FCAGSTFISDEVARDLSLQFKRPINPTDQS+Y+VDSVTVKNG++HLYFDKAGQKTYERH
Sbjct 2429 FCAGSTFISDEVARDLSLQFKRPINPTDQSAYVVDSVTVKNGALHLYFDKAGQKTYERHP 2488
Query 2518 LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALV 2577
LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES+AKSASVYYSQLMCQPILLLDQALV
Sbjct 2489 LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESAAKSASVYYSQLMCQPILLLDQALV 2548
Query 2578 SDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAA 2637
SDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF+SAA
Sbjct 2549 SDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAA 2608
Query 2638 RQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSAR 2697
RQG VD+DV+TKDV+ECLKLSH SDIEVTGDSCNN+MLTYNKVENMTPRDLGACIDC+AR
Sbjct 2609 RQGVVDTDVDTKDVIECLKLSHHSDIEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNAR 2668
Query 2698 HINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTK 2757
HINAQVAKSHN++L+WNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV+TTK
Sbjct 2669 HINAQVAKSHNVSLVWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTK 2728
Query 2758 IALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVT 2817
I+LKGGK+V+ W K L+KVTL+ + A Y+I PVH +S H +++EIIGYKAI GVT
Sbjct 2729 ISLKGGKVVSTWFKLLLKVTLLCVLAALFCYVIMPVHSLSVHDGYTNEIIGYKAIQDGVT 2788
Query 2818 RDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTT 2877
RDI STD CFANKHA FD+WFSQRGGSY NDK CP++AA+ITRE+GF+VPGLPGT+LR
Sbjct 2789 RDIVSTDDCFANKHAGFDSWFSQRGGSYRNDKNCPVVAAIITREIGFIVPGLPGTVLRAL 2848
Query 2878 NGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTN 2937
NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYCYDTN
Sbjct 2849 NGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTN 2908
Query 2938 VLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVC 2997
+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE GVC
Sbjct 2909 LLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGVC 2968
Query 2998 VSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVV 3057
+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+AI+V
Sbjct 2969 LSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILV 3028
Query 3058 TCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLT 3117
TC AYYFM+FRRAFGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYS+ YLYLTFY T
Sbjct 3029 TCAAYYFMKFRRAFGEYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFYLYLTFYFT 3088
Query 3118 NDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEE 3177
NDVSFLAH+QW MF+P+VPFWIT Y+ CIS KHF+WFFSNYLK+RV+FNGV+FSTFEE
Sbjct 3089 NDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHFHWFFSNYLKKRVMFNGVTFSTFEE 3148
Query 3178 AALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKA 3237
AALCTFLLNKEMYL+LRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCHLAKA
Sbjct 3149 AALCTFLLNKEMYLRLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKA 3208
Query 3238 LNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD 3297
LNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD
Sbjct 3209 LNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD 3268
Query 3298 VVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTA 3357
VYCPRHV+CT+EDMLNPNY+DLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+
Sbjct 3269 TVYCPRHVVCTAEDMLNPNYDDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTS 3328
Query 3358 NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDY 3417
NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDY
Sbjct 3329 NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDY 3388
Query 3418 DCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVIN 3477
DCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVIN
Sbjct 3389 DCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVIN 3448
Query 3478 GDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQN 3537
GDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQN
Sbjct 3449 GDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQN 3508
Query 3538 GMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQS 3597
GMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+LVQS
Sbjct 3509 GMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQS 3568
Query 3598 TQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPA 3657
TQWSLFFF+YENAFLPFA+GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMVYMPA
Sbjct 3569 TQWSLFFFVYENAFLPFALGIMAVAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPA 3628
Query 3658 SWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTL 3717
SWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMNV+TL
Sbjct 3629 SWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITL 3688
Query 3718 VYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQ 3777
VYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITGNTLQ
Sbjct 3689 VYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQ 3748
Query 3778 CIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDA 3837
CIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+SIDA
Sbjct 3749 CIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDA 3808
Query 3838 FKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHND 3897
FKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHND
Sbjct 3809 FKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHND 3868
Query 3898 ILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAF 3957
ILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA+
Sbjct 3869 ILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAY 3928
Query 3958 ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQAR 4017
ATAQEAYEQAV+NGDSEVVLKKLKKSLNVAKSEFD DAAMQRKLEKMADQAMTQMYKQAR
Sbjct 3929 ATAQEAYEQAVSNGDSEVVLKKLKKSLNVAKSEFDHDAAMQRKLEKMADQAMTQMYKQAR 3988
Query 4018 SEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDY 4077
SEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV+PDY
Sbjct 3989 SEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDY 4048
Query 4078 NTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAV 4137
TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRANSAV
Sbjct 4049 GTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRANSAV 4108
Query 4138 KLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFP 4197
KLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN KGGRFVLALLSD QDLKWARFP
Sbjct 4109 KLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNAKGGRFVLALLSDHQDLKWARFP 4168
Query 4198 KSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNA 4257
KSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNA
Sbjct 4169 KSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNA 4228
Query 4258 TEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMD 4317
TEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMD
Sbjct 4229 TEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMD 4288
Query 4318 QESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWK 4377
QESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVCGMWK
Sbjct 4289 QESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWK 4348
Query 4378 GYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGF 4437
GYGCSCDQLREPM+QSADA +FLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYN+KVAGF
Sbjct 4349 GYGCSCDQLREPMMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGF 4408
Query 4438 AKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFR 4497
AKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+K+CPAVA HDFFKFR
Sbjct 4409 AKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLIKECPAVAVHDFFKFR 4468
Query 4498 IDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDF 4557
+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDD+YFNKKDWYDF
Sbjct 4469 VDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDNYFNKKDWYDF 4528
Query 4558 VENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQT 4617
VENPD+LRVYANLGERVR+ALLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWYDFGDF+Q
Sbjct 4529 VENPDVLRVYANLGERVRRALLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQV 4588
Query 4618 TPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDR 4677
PG GVP+VDSYYSLLMPILTLT+AL AESH+D DL KP +KWDLLKYDFTEERL LFDR
Sbjct 4589 APGCGVPIVDSYYSLLMPILTLTKALAAESHMDADLAKPLVKWDLLKYDFTEERLCLFDR 4648
Query 4678 YFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTG 4737
YFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTG
Sbjct 4649 YFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTG 4708
Query 4738 YHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNV 4797
YHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNV
Sbjct 4709 YHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNV 4768
Query 4798 AFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCD 4857
AFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCD
Sbjct 4769 AFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCD 4828
Query 4858 IRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQD 4917
IRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQD
Sbjct 4829 IRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQD 4888
Query 4918 ALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGA 4977
ALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGA
Sbjct 4889 ALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGA 4948
Query 4978 TVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTC 5037
TVVIGTSKFYGGWHNMLKTVYSDVE+PHLMGWDYPKCDRAMPNMLRIMASL+LARKH+TC
Sbjct 4949 TVVIGTSKFYGGWHNMLKTVYSDVESPHLMGWDYPKCDRAMPNMLRIMASLILARKHSTC 5008
Query 5038 CSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVN 5097
C+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVN
Sbjct 5009 CNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVN 5068
Query 5098 ALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVC 5157
ALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV+EFYAYLRKHFSMMILSDDAVVC
Sbjct 5069 ALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVC 5128
Query 5158 FNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDD 5217
+NS YA+QGLVASIKNFK+VLYYQNNVFMSEAKCWTETDLT+GPHEFCSQHTMLVKQGDD
Sbjct 5129 YNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTRGPHEFCSQHTMLVKQGDD 5188
Query 5218 YVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYL 5277
YVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYL
Sbjct 5189 YVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYL 5248
Query 5278 QYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTS 5337
QYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTS
Sbjct 5249 QYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTS 5308
Query 5338 LRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCK 5397
LRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCK
Sbjct 5309 LRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCK 5368
Query 5398 SHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLF 5457
SHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLF
Sbjct 5369 SHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLF 5428
Query 5458 AAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKV 5517
AAETLKATEETFKLSYGIATVREVLSDREL+LSWEVGKPRPPLNRNYVFTGYRVTKNSKV
Sbjct 5429 AAETLKATEETFKLSYGIATVREVLSDRELYLSWEVGKPRPPLNRNYVFTGYRVTKNSKV 5488
Query 5518 QIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLY 5577
QIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLY
Sbjct 5489 QIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLY 5548
Query 5578 PTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAA 5637
PTLNIS+EFSSNVANYQK+GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAA
Sbjct 5549 PTLNISNEFSSNVANYQKIGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAA 5608
Query 5638 VDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVF 5697
VDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVF
Sbjct 5609 VDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVF 5668
Query 5698 DEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIG 5757
DEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIG
Sbjct 5669 DEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIG 5728
Query 5758 PDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQI 5817
PDMFLGTCRRCPAEIVDTVSALVYDNKLKAHK+KSAQCFKM+YKGVITHDVSSAINRPQI
Sbjct 5729 PDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKEKSAQCFKMYYKGVITHDVSSAINRPQI 5788
Query 5818 GVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETA 5877
GVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETA
Sbjct 5789 GVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETA 5848
Query 5878 HSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCS 5937
HSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLE+PRRNVATLQAENVTGLFKDCS
Sbjct 5849 HSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEVPRRNVATLQAENVTGLFKDCS 5908
Query 5938 KVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
K+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM
Sbjct 5909 KIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5968
Query 5998 FITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTD 6057
FITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAVPTGYVDT N+T+
Sbjct 5969 FITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENSTE 6028
Query 6058 FSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFEL 6117
F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFVLWAHGFEL
Sbjct 6029 FTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFEL 6088
Query 6118 TSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGN 6177
TSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPFMIDVQQWGFTGN
Sbjct 6089 TSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGN 6148
Query 6178 LQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKV 6237
LQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDELKINAACRKV
Sbjct 6149 LQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELKINAACRKV 6208
Query 6238 QHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYAT 6297
QHMVVK+ALLADKF VLHDIGNPKAI+CVPQA+V+WKFYDAQPCSDKAYKIEELFYSYAT
Sbjct 6209 QHMVVKSALLADKFTVLHDIGNPKAIRCVPQAEVDWKFYDAQPCSDKAYKIEELFYSYAT 6268
Query 6298 HSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFD 6357
H DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFD
Sbjct 6269 HHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFD 6328
Query 6358 KSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYR 6417
KSAF +LKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYR
Sbjct 6329 KSAFTHLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYR 6388
Query 6418 LYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVS 6477
YLDAYNMMISAGFSLW+YKQFDTYNLWNTFT+LQSLENVA+NVVNKGHFDGQ GE PVS
Sbjct 6389 QYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTKLQSLENVAYNVVNKGHFDGQSGEAPVS 6448
Query 6478 IINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVI 6537
IINN VYTKVDG+DVE+FENKTTLPVNVAFELWAKRNIKPVPE+KILNNLGVDIAAN VI
Sbjct 6449 IINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANNVI 6508
Query 6538 WDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITE 6597
WDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ L V FDGRV+GQVD FRNARNGVLITE
Sbjct 6509 WDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLIVLFDGRVEGQVDFFRNARNGVLITE 6568
Query 6598 GSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKP 6657
GSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQSR+L++FKP
Sbjct 6569 GSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKP 6628
Query 6658 RSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFEL 6717
RSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR ++S +L
Sbjct 6629 RSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSLLKL 6688
Query 6718 EDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYT 6777
EDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDY
Sbjct 6689 EDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYA 6748
Query 6778 EISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKG 6837
EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG++A +PKG
Sbjct 6749 EISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKG 6808
Query 6838 IMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSD 6897
IMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSD
Sbjct 6809 IMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSD 6868
Query 6898 LNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQ 6957
LNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTK+V K+NDSKEGFFTY+CGFI+Q
Sbjct 6869 LNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKHVLKDNDSKEGFFTYLCGFIKQ 6928
Query 6958 KLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQI 7017
KLALGGSVA+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NYLGKP+EQI
Sbjct 6929 KLALGGSVAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGVNYLGKPKEQI 6988
Query 7018 DGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGR 7077
DGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI SLL KGR
Sbjct 6989 DGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGR 7048
Query 7078 LIIRENNRVVISSDVLVNN 7096
LIIRENNRVV+SSD+LVNN
Sbjct 7049 LIIRENNRVVVSSDILVNN 7067
>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182
Score = 8972 bits (23282), Expect = 0.0, Method: Composition-based stats.
Identities = 3283/7282 (45%), Positives = 4490/7282 (62%), Gaps = 327/7282 (4%)
Query 9 NEKT--HVQLSLPVLQVRDVLV---RGFGDSVEEVLSEARQHLKDGTCGLV--EVEKGVL 61
EK HV L + D+++ F D E + L G+ L + KG +
Sbjct 22 TEKRTDHVSLKASLCDAGDLVLKISPWFMDG-ESAYKHVSEQLSKGSKLLFVPQTLKGFI 80
Query 62 PQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETL-----GVLVPHVGEIPV 116
L P V++ MV +A G G TL G+ P ++
Sbjct 81 RHLPGPRVYLVERLTGGTYSDPFMVNQLAYQNAAGEGVIGTTLQGKRVGMFFPFDADLVT 140
Query 117 AYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRE 176
+ LLRK KG GG+ + D + PY D + ++ L+++
Sbjct 141 GEFQFLLRK---KGFGGNRFR------DAPWDYNWTPYSDLMDALEADPCGKYSQSLLKK 191
Query 177 LNGGAYTRYVDNNFCGPDGYPLECIKDLLARAG--KASCTLSEQLDFIDTKRGVYCCREH 234
L GG +T +D CG +G P+ L+A G K + +E D+ R + +
Sbjct 192 LVGGDFTP-IDQYMCGKNGKPIAEFAALMASEGITKLADVEAEVKSRTDSDRYI-VFKNK 249
Query 235 EHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLD 294
+ I W +R + +Y Q+ F + + DT + P F + S I+ I P +
Sbjct 250 LYRIVWNVQRKDVAYSKQSAFTMNSIVQLDTME-DVPRHSFTIGSEIQVIAPSTAVQANG 308
Query 295 GFMGRIRSVYPVASPN---ECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTK 351
+ R +Y E N + S + C CG+ SW TG+ V+ CG
Sbjct 309 HLNLKQRLLYAFYGKQAVSEPNYIYHSAYVDCTSCGKGSWLTGNAVQGFACDCGAHYCAN 368
Query 352 E-GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRT--IAFGG 408
+ + G + +NAV+ CP + E +H+L + + K + G+T + +GG
Sbjct 369 DVDLQSSGLVRKNAVLLTTCPCNKDGEC--KHTLPQLVSMMTDKCDVEVVGKTFILTYGG 426
Query 409 CVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEKVNINIV 464
+++Y+GC +++PRA + + + G G + E L++ + IN V
Sbjct 427 VIYAYMGCSGGTMHFIPRAKSCVS-KIGDAIFTGCTGTWSKVCETANLFLERAQHAINFV 485
Query 465 GDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIG 524
+F L E + +L+ ++S + + ++ + + G + VT G +G N+G
Sbjct 486 NEFVLTETVVALLSGTTSSIEELRDLCRNATFEKVRDYLTPRG-WIVTMGSYIEGVINVG 544
Query 525 EQKSILSPLYA-----------FASEAARVVR--SIFSRTLETAQNSVRVLQKAAITILD 571
+ L A F AA + S TL+ +S+ + I
Sbjct 545 AAGVCNAALNAPFIVLSGLGESFKKVAATPWKLCSSLRETLDHYADSI-TYRVFPYDIPC 603
Query 572 GISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWL 631
++ Y+ L+D + T + V Y+ V QLT+ +F + + +
Sbjct 604 DVTDYTALLLDCAVLTGA---SAYFVARYVDEKVEQLTNL----VFSSCQSAVAAFVQAC 656
Query 632 EEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCAD 691
+K +F+ D + ++K +S V + ++ F +++K + L
Sbjct 657 MSTYKATAKFISDMFTLIKVVSERLYVYTSVGFVVVGDYSSQLLKQFMHILSKAMQLLHT 716
Query 692 SIIIGGAKLKAL--NLGETFVTHSKGLYRKCVKSR---EETGLLMPLKAPKEIIFL---- 742
++ G+KL ++ N ++ V S Y + R ++ L++P K+ I +
Sbjct 717 TVSWAGSKLPSVVYNGRDSLVFPSGTYYCVSTQGRSLQDQFDLVIPGDLSKKQIGILEPT 776
Query 743 -EGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLE-IKDTEK-Y 799
T+ ++ T V + G L+P ++ + E +VG V I+ + + ++D+E +
Sbjct 777 PNSTTVDKKINTNVVEVVVGQLEPTKEHSPEL----VVGDYVIISNKIFVRSVEDSETVF 832
Query 800 CALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSVNITFELDERIDKVL-NEKC 857
L + + F LKGGAP K V FG + E+ +SV++ +++ +D +L +
Sbjct 833 YPLCTDGKIVPTLFRLKGGAPPKGVKFGGEQTKEITAVRSVSVDYDVHPVLDALLAGSEL 892
Query 858 SAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLA 917
+ +TVE V +F VV D VI+ L + G DL++++ Y+++ G+ +
Sbjct 893 ATFTVEKDLPVKDFVDVVKDEVIELLSKLLRGYNVDGFDLEDFADTPCYVYNAEGDLAWS 952
Query 918 SHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEE 977
S M S P +E EEE D + E E ++ ED+ + A A+ P E+ +
Sbjct 953 STMTFSVNPVEEVEEECDDDYVEDEYLSEEMLVEEDEN-----SWAAAVEAVIPMEDVQL 1007
Query 978 DWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDN 1037
D L + + D +E T VEV +E + V EV S
Sbjct 1008 DTLVAEIDVSEPADDVAEQAST----EEVEVPSACVLEASQVANAAEVESCEA------- 1056
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
E + + NAA A + A ++ +
Sbjct 1057 ---------EVSSSIPLHEDANAA-----------KANDCAEGMPALDSTETVSKLSVDT 1096
Query 1098 KVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGAD 1157
VG + + + + + ++ P
Sbjct 1097 PVGDVTQDDATSSNATVIS---------------EDVHTATHSKGLVAVP-------EVV 1134
Query 1158 PIHSLRVCVDTVRTN---VYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPF 1214
P +L V+ +R+ + K +V + ++V++ AE P + K
Sbjct 1135 PEKALGTSVERMRSTSEWTVVETSLKQETAVIVKN-DSSAKPQRVKKPKAENPLKNFKHI 1193
Query 1215 ITESKPSVEQ--RKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGNLHPDSATLVS 1272
+ + ++ + + C+ +L I + S LV
Sbjct 1194 VLNNDVTLVFGDAIAVARATEDCIL--------VNAANTHLKHGGGIAAAIDRASGGLVQ 1245
Query 1273 DIDITFLKKDAPYIVGD-VVQEGVLTA-----VVIPTKKAGGTTEMLA---KALRKVPTD 1323
++ P VGD + +G A VV P +A ++L KA K P
Sbjct 1246 AESDDYVNFYGPLNVGDSTLLKGHGLATGILHVVGPDARANQDIQLLKRCYKAFNKYPL- 1304
Query 1324 NYITTYPGQGLN--------GYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNL 1375
++ G+ Y + T ++ + + + + L
Sbjct 1305 -VVSPLISAGIFCVEPRVSLEYLLSVVHTKTYVVVNSEKVYNDLAAPKPPTGLTYSHEGW 1363
Query 1376 REMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLI 1435
R ++ +A+ +C + A ++ + + + VD G ++Y Y+SK + +I
Sbjct 1364 RGIIRNAKSFGFTCFICTDQSANAKLLKGRGVDLTKKTQTVD-GVKYYLYSSKDPLTDII 1422
Query 1436 NTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSK 1495
N + + MP+GYVTHGL+L +A + ++ + VP ++S D V N + + +
Sbjct 1423 TAANAC-KGICAMPIGYVTHGLDLAQAGQQVKKITVPYVCLLASKDQVPILNSDV--AVQ 1479
Query 1496 TPEEHFIETISLAGSYKDWSY-SGQSTQLGI---EFLKRGDKSVYYTSNPTTFHLDGEVI 1551
TPE+ FI T+ G Y W +G+ G+ + L D+++ Y N +
Sbjct 1480 TPEQSFINTVIANGGYHCWHLVTGELIVKGVSYRKLLNWSDQTICYADNKFYVVKGQIAL 1539
Query 1552 TFDNLKTLLSLR-----EVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTK 1606
FD+L+ + + + + V T+D +N T V++ + TY Q G + G+D++
Sbjct 1540 PFDSLEKCRTYLTSRAAQQKNVDVLVTIDGVNFRTVVLNNTTTYRVQLGSVFYKGSDISD 1599
Query 1607 IKPHNSHEGKTFYVLPNDD-TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLT 1665
P G+ Y+ N + E Y T D +FL RY S L KKWKY +G+
Sbjct 1600 TIPTEKMSGEAVYLADNLSEAEKAVLSEVYGTADTAFLHRYYSLLALVKKWKYTVHDGVK 1659
Query 1666 SIKWADNNCYLATALLTLQQI-ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGE 1724
S+K NNCY+ +L L + E+KF PALQ AY + + G++ F ALI+AY + T GE
Sbjct 1660 SLKLNSNNCYVNVTMLMLDMLKEIKFIVPALQAAYLKHKGGDSTEFIALIMAYGDCTYGE 1719
Query 1725 LGDVRETMSYLFQHANLDS-CKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGV 1783
D + + A L + K V C CG Q TT G++A +Y+G S ++
Sbjct 1720 PDDASRLLHTILSKAELTTQAKMVWRQWCNVCGVQDTTTTGLKACIYVGMNSLDELHATH 1779
Query 1784 QIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTG-------NYQCGHY 1836
+ C CG + LV+ +P++++S + + + +YT GHY
Sbjct 1780 EECCQCGDVRKRQLVEHNAPWLLLSGLNEAKVMTPTSQSAGPDYTAFNVFQGVETSVGHY 1839
Query 1837 KHITSKETL-YCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPK 1895
H+ K+ L Y D L+K+S+ K +TDV+Y + Y+ V Y LDG ++DP
Sbjct 1840 LHVRVKDNLLYKYDSGSLSKTSDMKCKMTDVYYPKQRYSADCNVVVYSLDGNTWADVDPD 1899
Query 1896 LDNYYKKDNSYFTEQP-IDLVPNQPYPNASFDNFKFVCDN-----IKFADDLNQLTGYK- 1948
L +Y KD YFT++P I+ P + + N V + + N L G+
Sbjct 1900 LSAFYMKDGKYFTKKPVIEYSPATILSGSVYTNSCLVGHDGTIGSDAISSSFNNLLGFDN 1959
Query 1949 -KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNT 2007
KP S++L +FFPD GDV+ +Y Y P +K GA L KPI+W N+ + A K N
Sbjct 1960 SKPVSKKLTYSFFPDFEGDVILTEYSTYDPIYKNGAMLHGKPILWVNNSKFDSALNKFNR 2019
Query 2008 WCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC-EDLKPVSE-EVVENPTIQKDVLECN 2065
+R ++ PV N + VL+ Q ++ A ED KP S +V E+ + +++C
Sbjct 2020 ATLRQVYDIAPVTLENKYTVLQDNQIQQVEVEAPKEDAKPQSPVQVAEDIDNKLPIIKCK 2079
Query 2066 VKTTEVVGD-IILKPANNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLA 2123
V D + + + +G DL A YVD N L + K N S + + T+
Sbjct 2080 GLKKPFVKDGYSFVNDPQGVNVIDTLGIDDLRALYVDRNLRLIVLKENNWSALFNIHTVE 2139
Query 2124 THGLAAVNSVPWDT----IANYAKPFLNKVVSTTTNIVT---RCLNRVCTNYMP------ 2170
L+ + + T I A + S T N+ T + L R+ N +
Sbjct 2140 KGDLSVIAASGSITRRVKILLGASSLFAQFASVTVNVTTAMGKALGRMTRNVITNTGIIG 2199
Query 2171 YFFTLLLQL----CTFTRSTN-SRIKASMPTTIAKNTVKS-VGKFCLEASFNYLKSPNFS 2224
F LL L TF +S N S +K + V + V K C A+++ L F
Sbjct 2200 QGFALLKMLLILPFTFWKSKNQSTVKVEVGALRTAGIVTTNVVKQCASAAYDVL-VVKFK 2258
Query 2225 KLINIIIWFLLLSVC------------------LGSLIYSTAALGVLM------SNLGMP 2260
++ LL +C L S + A G+L S LG+
Sbjct 2259 RIDWKSTLRLLFLICTTGLLLSSLYYLFLFHQVLTSDVMLDGAEGMLATYRELRSYLGIH 2318
Query 2261 SYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLT 2319
S C G E Y N + + +C+ S C+ CL G DSL Y + + IQ ++S+ ++
Sbjct 2319 SLCDGMVEAYRN-VSYDVNDFCSNRSALCNWCLIGQDSLTRYSAFQMIQTHVTSYVINID 2377
Query 2320 AFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFA--VHFISNSWLMWLIINLVQMAPI 2377
V E+ LAY+L+T F VL L Q FFSY V++ S ++L+ V P+
Sbjct 2378 WVWFVMEFALAYVLYTSTFNVLLLVVSSQYFFSYTGAFVNWRSYNYLVSGYFFCVTHIPL 2437
Query 2378 SAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVY 2437
+VR+Y F A +++ + Y HV++GC + C++CYKRNR TRVE +T+V G +R+FY+
Sbjct 2438 LGLVRIYNFLACLWFLRRFYNHVINGCKDTACLLCYKRNRLTRVEASTVVCGSKRTFYIV 2497
Query 2438 ANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVK 2497
ANGG FC HNWNCV+CDT G+TFI +EVA DL+ +R + PTD+S Y V+SVTVK
Sbjct 2498 ANGGTSFCCRHNWNCVDCDTAGIGNTFICEEVANDLTTSLRRLVKPTDKSHYYVESVTVK 2557
Query 2498 NGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANN----TKGSLPINVIVFDGKSKCEESS 2553
+ + L++ + G YER+ L +F NLD L+ G N +++D + +E+
Sbjct 2558 DSVVQLHYSREGASCYERYPLCYFTNLDKLKFKEVCKTPTGIPEHNFLIYDSSDRGQENL 2617
Query 2554 AKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLV 2613
A+SA VYYSQ++ +P+LL+D +V+ VGDS E+A KM D+YVN+F S F V +KL LV
Sbjct 2618 ARSACVYYSQVLSKPMLLVDSNMVTTVGDSREIASKMLDSYVNSFISLFGVNRDKLDKLV 2677
Query 2614 ATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNN 2672
ATA + + V+ TF AAR V+SDVET +V+ L+ +++ D+++T + NN
Sbjct 2678 ATARDCVKRGDDFQTVIKTFTDAARGPAGVESDVETSSIVDALQYAYKHDLQLTTEGFNN 2737
Query 2673 YMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSA 2732
Y+ +Y K +++ DLG ID +A +N ++ N A IWN D+M LS+ L++QIR A
Sbjct 2738 YVPSYIKPDSVATADLGCLIDLNAASVNQTSIRNANGACIWNSSDYMKLSDSLKRQIRIA 2797
Query 2733 AKKNNLPFKLTCATTRQVVNVVTTKIAL-KGGKIVNNWL--------KQLIKVTLVFLFV 2783
+K N+PF+LT + R N+++ K + K WL K VTLV +
Sbjct 2798 CRKCNIPFRLTTSRLRSADNILSVKFSATKLSGGAPKWLLKLRDFTWKSYCVVTLVVFAM 2857
Query 2784 AAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQR-G 2842
A + YL P MS+ + I+ YK ++ G+ RDI +DTCFANK+ F WF++ G
Sbjct 2858 AVLSYLCLPAFNMSQVSFHEDRILTYKVVENGIIRDITPSDTCFANKYQSFSKWFNEHYG 2917
Query 2843 GSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKL 2902
G + ND +CP+ AVI G VP LP + + F+ RVF++ N+CYTP+
Sbjct 2918 GLFNNDISCPVTVAVIAGVAGARVPNLPANVAWV-GRQIVLFVSRVFASSNNVCYTPTAE 2976
Query 2903 IEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-I 2961
I Y F+ S CVLA+ECT+F+DA GK PYCYD VL G+ AY+ ++P RY + D
Sbjct 2977 IPYERFSDSGCVLASECTLFRDAEGKINPYCYDPTVLPGASAYDQMKPHVRYDMYDSDMY 3036
Query 2962 IQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGV 3021
I+FP E ++R+ T + YCR G+CE + GVC++T+G W + ND+Y + PGV+CG
Sbjct 3037 IKFPEVVFESTLRITKTLATRYCRFGSCEDANEGVCITTNGSWAIYNDHYANKPGVYCGD 3096
Query 3022 DAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFN 3081
+ +++ + L QP+ +S S+ G ++ I +T YY + +RA +Y+
Sbjct 3097 NYFDIVRRLGLSLFQPVTYFQLSTSLALGVMLCIFLTIAFYYVNKVKRALADYTQCAVVA 3156
Query 3082 TLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWIT 3141
L++ LC L Y+ +Y Y TFYLT + +F+ H+ W VMF +VP W+
Sbjct 3157 VAAALLNSLCLCFVVSNPLLVLPYTALYYYATFYLTGEPAFVMHVSWFVMFGTVVPIWMV 3216
Query 3142 IAYIICISTKHFYWFFSNYLKRRV--VFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLL 3199
AYI+ + +H W + + K+ V +G +F++AA F++NK+ Y+ LR+ +
Sbjct 3217 FAYIVGVCLRHLLWVMAYFSKKHVEVFTDGKLNCSFQDAAANIFVINKDTYVALRNSI-- 3274
Query 3200 PLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITS 3259
YNRYL+++NKYKY+SGAMDT SYREA+ HL KAL +S +GSDVL+QPP S+TS
Sbjct 3275 TQDSYNRYLSMFNKYKYYSGAMDTASYREASAAHLCKALQVYSETGSDVLFQPPNCSVTS 3334
Query 3260 AVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYED 3319
+VLQSG KMA PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+
Sbjct 3335 SVLQSGLVKMAAPSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDA 3394
Query 3320 LLIRKSNHNFLVQAG---NVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFS 3376
LL+ K+N +F+VQ LRV+GH+M +LKL V++ANP+TP Y F ++PG +FS
Sbjct 3395 LLVSKTNLSFIVQKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFS 3454
Query 3377 VLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHA 3436
VLACYNG P+GV+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H
Sbjct 3455 VLACYNGRPTGVFMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHT 3514
Query 3437 GTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLV 3496
G +G YG F DRQ Q +D T+N++AWLYAA++NG WF+ T + FN
Sbjct 3515 GCAFDGVMYGAFEDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEW 3574
Query 3497 AMKYNYE-PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFT 3555
AM + + VD+ L+ +TG++V + +++ L G G+TILG+++LEDEFT
Sbjct 3575 AMSNQFTEFIGTQSVDM---LAHKTGVSVEQLLYAIQTL-HKGFQGKTILGNSMLEDEFT 3630
Query 3556 PFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFA 3615
P DV Q GV QS VKR G HWL T+L + + +Q T+++++ +L+E L
Sbjct 3631 PDDVNMQVMGVVMQSGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLT 3690
Query 3616 MGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVD 3671
++ + A M+ VKHKH FL LFLLP+ + Y N+VY P +S ++ + WL+
Sbjct 3691 PLVLCVMACVMLTVKHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPAS 3750
Query 3672 TSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAI 3731
+ D +Y S L ++ R + + L + + Y G+ +
Sbjct 3751 VYMRTTH-TDLGVYLSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPL 3808
Query 3732 SMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCT 3791
+ + ++TS+Y+ V + +A+ + Y P ++ ++L+Y +GYFCT
Sbjct 3809 TYLMFLTTLTSDYTVTVFLAVNVAKFFARVVFLYAPHAGFIFPEVKLVLLMYLAVGYFCT 3868
Query 3792 CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKP 3851
YFG+F LLN R+ LGVYDY VSTQEFRY+ GL P+NS +A +LN+KL+G+GG P
Sbjct 3869 VYFGVFSLLNLKLRVPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTP 3928
Query 3852 CIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKM 3911
CIK+A+VQSK++D+KCTSVVLLSVLQQL +E++SK WA CV+LHNDIL A D TEAF+
Sbjct 3929 CIKIASVQSKLTDLKCTSVVLLSVLQQLHLEANSKAWAHCVKLHNDILAATDPTEAFDNF 3988
Query 3912 VSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANG 3971
V L + L+S VD+ L ++LD+ + LQA SEFS L SYA AQ +Y++A+ +G
Sbjct 3989 VCLFATLMSFSANVDLEALASDLLDHPSVLQATLSEFSHLASYAELEAAQSSYQKALNSG 4048
Query 3972 D-SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQ 4030
D S VLK L+K++N+AK+ +++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQ
Sbjct 4049 DASPQVLKALQKAVNIAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQ 4108
Query 4031 TMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFT 4090
TMLF M++KLDND LN +I+NAR+GCVPL+++PL + KL VVIPD + + +
Sbjct 4109 TMLFGMIKKLDNDVLNGVISNARNGCVPLSVVPLCASNKLRVVIPDITIWNKVVTWPSLS 4168
Query 4091 YASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA-NSAVKLQNNELSPVAL 4149
YA ALW+I + + D ++V+ S+++ + + +L WPL++ RA +SAV LQNNE+ P L
Sbjct 4169 YAGALWDISLINNVDGEVVKSSDVT-ETNESLTWPLVLECTRAASSAVTLQNNEIRPSGL 4227
Query 4150 RQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTEL 4209
+ M +AG C + ++LAYY +G + ++ +LS+ LKWA+ DG + EL
Sbjct 4228 KTMVVSAGIDHANC-NTSSLAYYEPVEGRKMLMGILSENAHLKWAKVEGRDGF--VNIEL 4284
Query 4210 EPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSF 4269
+PPC+F+ PKGP+V+YLYF+K LNNL+RG +LG +AATVRLQAG+ TE NS+VLS
Sbjct 4285 QPPCKFLIAGPKGPEVRYLYFVKNLNNLHRGQLLGHIAATVRLQAGSNTEFAINSSVLSA 4344
Query 4270 CAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLY 4329
F+VD KAY D++ +GG P+TNCVKML TGTG A++V PEAN DQ+++GGAS CLY
Sbjct 4345 VTFSVDPGKAYLDFVNAGGAPLTNCVKMLTPKTGTGIAVSVKPEANADQDTYGGASVCLY 4404
Query 4330 CRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREP 4389
CR HI+HP+ G C KGK+VQ+P DPVGF L+NT C VC W G+GC+CD LR
Sbjct 4405 CRAHIEHPDVTGVCKFKGKFVQVPL-HIRDPVGFCLQNTPCNVCQFWIGHGCNCDALRGT 4463
Query 4390 MLQSADAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYN--DKVAGFAKFLKTNCC 4446
+ + +FLNRV G AR+ PC +G +TDVV+RAFDI N KVAG K+ KTN C
Sbjct 4464 TIPQSKDSNFLNRVRGSIVNARIEPCASGLTTDVVFRAFDICNYKAKVAGIGKYYKTNTC 4523
Query 4447 RFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHI 4506
RF E D++ + +DS+FVVKRHT NY+ E+ Y+L+KDC AVA HDFF F +D PHI
Sbjct 4524 RFVEVDDEGHRLDSFFVVKRHTMENYELEKRCYDLVKDCDAVAVHDFFIFDVDKVKTPHI 4583
Query 4507 SRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRV 4566
RQRLT+YTM DLVYALRHFD+ NC+ LK ILV Y CCD YF+ K W+DFVENP+++ V
Sbjct 4584 VRQRLTEYTMMDLVYALRHFDQNNCEVLKSILVKYGCCDASYFDNKLWFDFVENPNVISV 4643
Query 4567 YANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVV 4626
Y LGER+RQA+L TV+FCD M +G+VGVLTLDNQDLNG WYDFGDF+ T PG+GV +V
Sbjct 4644 YHKLGERIRQAVLNTVKFCDQMVKSGLVGVLTLDNQDLNGKWYDFGDFVITQPGAGVAIV 4703
Query 4627 DSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTY 4686
DSYYS LMP+L++T L AE+H D DLTKP I+W LL+YD+T+ ++ LF++YFK WDQ Y
Sbjct 4704 DSYYSYLMPVLSMTNCLAAETHRDCDLTKPLIEWPLLEYDYTDYKIGLFEKYFKXWDQQY 4763
Query 4687 HPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVV 4746
HPNCVNC DDRC+LHCANFNVLFS P TSFGP+VRKIFVDGVPFV+S GYH++ELG+V
Sbjct 4764 HPNCVNCTDDRCVLHCANFNVLFSMTLPGTSFGPIVRKIFVDGVPFVISCGYHYKELGLV 4823
Query 4747 HNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGN 4806
N DV+LH RLS KEL++YAADPAMH AS + L D RT CFSVAALT + FQTV+PGN
Sbjct 4824 MNMDVSLHRHRLSLKELMMYAADPAMHIASASALWDLRTPCFSVAALTTGLTFQTVRPGN 4883
Query 4807 FNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVE 4866
FNKDFYDF VSKGFFKEGSSV L+HFFFAQDG+AAI+DY YY YNLPTMCDI+Q+LF +E
Sbjct 4884 FNKDFYDFVVSKGFFKEGSSVTLRHFFFAQDGHAAITDYSYYAYNLPTMCDIKQMLFCME 4943
Query 4867 VVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRN 4926
VVD+YF+ YDGGC+NA++VIVNNLDKSAG PFNK+GKAR+YY+S+SY++QD LFA TKRN
Sbjct 4944 VVDRYFEIYDGGCLNASEVIVNNLDKSAGHPFNKFGKARVYYESLSYQEQDELFAMTKRN 5003
Query 4927 VIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKF 4986
V+PTITQMNLKYAISAKNRARTVAGVSI STMTNRQ+HQK+LKS+AATRG+T VIGT+KF
Sbjct 5004 VLPTITQMNLKYAISAKNRARTVAGVSILSTMTNRQYHQKMLKSMAATRGSTCVIGTTKF 5063
Query 4987 YGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYR 5046
YGGW MLKT+Y DV+NPHLMGWDYPKCDRAMPNM RI ASL+LARKH+TCC+ + RFYR
Sbjct 5064 YGGWDFMLKTLYKDVDNPHLMGWDYPKCDRAMPNMCRIFASLILARKHSTCCTNTDRFYR 5123
Query 5047 LANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNK 5106
LANECAQVLSE V+CGG YVKPGGTSSGDATTAYANSVFNI QA TANV+AL+ +GN
Sbjct 5124 LANECAQVLSEYVLCGGGYYVKPGGTSSGDATTAYANSVFNILQATTANVSALMGANGNT 5183
Query 5107 IADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQG 5166
I D+ V+++Q LY +YR D FV+ +YA+L KHFSMMILSDD VVC+NS YA++G
Sbjct 5184 IVDEEVKDMQFELYVNVYRKSQPDPKFVDRYYAFLNKHFSMMILSDDGVVCYNSDYATKG 5243
Query 5167 LVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDP 5226
+ASI+NFK LYYQNNVFMSEAKCW ETDL KGPHEFCSQHT+ +K GDD +LPYPDP
Sbjct 5244 YIASIQNFKETLYYQNNVFMSEAKCWVETDLKKGPHEFCSQHTLFIKDGDDGYFLPYPDP 5303
Query 5227 SRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDE 5286
SRIL AGCFVDDIVKTDGTLM+ERFVSLAIDAYPLTKH + EY +VF +YLQYI KL+ +
Sbjct 5304 SRILSAGCFVDDIVKTDGTLMVERFVSLAIDAYPLTKHDDPEYQNVFWVYLQYIEKLYKD 5363
Query 5287 LTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRR 5346
LTGHMLD YSVML DN++++WE FY +YT T LQAVG+CV+C+SQTSLRCG CIRR
Sbjct 5364 LTGHMLDSYSVMLCGDNSAKFWEESFYRDLYTAPTTLQAVGSCVVCHSQTSLRCGTCIRR 5423
Query 5347 PFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFP 5406
PFLCCKCCYDHVI+T HK+VLSV+PYVCNAPGCDV DVT+LYLGGMSY+C H+P SFP
Sbjct 5424 PFLCCKCCYDHVIATPHKMVLSVSPYVCNAPGCDVADVTKLYLGGMSYFCIDHRPVCSFP 5483
Query 5407 LCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATE 5466
LCANG VFGLYKN C GS +VT+FN +ATCDWT +GDY LANT TE LKLFAAETL+ATE
Sbjct 5484 LCANGLVFGLYKNMCTGSPSVTEFNRLATCDWTESGDYTLANTTTEPLKLFAAETLRATE 5543
Query 5467 ETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEK 5526
E K SY IAT++E++ +REL L WE GK +PPLNRNYVFTGY +TKNSKVQ+GEY FE+
Sbjct 5544 EASKQSYAIATIKEIVGERELLLVWEAGKAKPPLNRNYVFTGYHITKNSKVQLGEYVFER 5603
Query 5527 GDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEF 5586
DY DAV Y+ +TTYKL VGD FVLTSH+V L APT+V QE YV+ITGLYPTL + +EF
Sbjct 5604 IDYSDAVSYKSSTTYKLAVGDIFVLTSHSVATLQAPTIVNQERYVKITGLYPTLTVPEEF 5663
Query 5587 SSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKAL 5646
+++VAN+QK G K+ T+QGPPGTGKSHFAIGLA+YYP+AR+VYTACSHAAVDALCEKA
Sbjct 5664 ANHVANFQKAGFSKFVTVQGPPGTGKSHFAIGLAIYYPTARVVYTACSHAAVDALCEKAF 5723
Query 5647 KYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNY 5706
KYL I KCSRIIPA+ARVEC+D+FKVN T QY+F T+NALPET+ADI+V DE+SM TNY
Sbjct 5724 KYLNIAKCSRIIPAKARVECYDQFKVNETNSQYLFSTINALPETSADILVVDEVSMCTNY 5783
Query 5707 DLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCR 5766
DLSV+NAR++AKH VY+GDPAQLPAPRTLLT+GTLEPE FNSV RLM +GPD+FL C
Sbjct 5784 DLSVINARIKAKHIVYVGDPAQLPAPRTLLTRGTLEPENFNSVTRLMCNLGPDIFLSVCY 5843
Query 5767 RCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTR 5826
RCP EIV+TVSALVY+NKL A K S QCFK+ YKG +THD SSAINRPQ+ V+ F+
Sbjct 5844 RCPEEIVNTVSALVYNNKLVAKKPASGQCFKILYKGSVTHDASSAINRPQLNFVKSFIAA 5903
Query 5827 NPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN 5886
NP W KAVFISPYNSQNAVA +LGL TQTVDSSQGSEY YVIF QT +TAH+ N+NRFN
Sbjct 5904 NPNWSKAVFISPYNSQNAVARSVLGLTTQTVDSSQGSEYPYVIFCQTADTAHANNINRFN 5963
Query 5887 VAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPT 5946
VA+TRA+ GILC+M+ + L+D L+F + + N LQ++ VTGL+KDCS+ +GLHP
Sbjct 5964 VAVTRAQKGILCVMTSQALFDSLEFAEVSL---NNYKLQSQIVTGLYKDCSRESSGLHPA 6020
Query 5947 QAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAI 6005
APT++SVD K+KT + LCV++ +P ++ Y R+IS MGFK++ + YP +FITR+EAI
Sbjct 6021 YAPTYVSVDDKYKTSDELCVNL-NVPANVPYSRVISRMGFKLDASIPNYPKLFITRDEAI 6079
Query 6006 RHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKP 6065
R VR+WIGFDVEG HA+R A GTN+PLQLGFSTGVN V P G VDT + + ++A+P
Sbjct 6080 RQVRSWIGFDVEGAHASRNACGTNVPLQLGFSTGVNFVVQPVGVVDTEWGSMLTSIAARP 6139
Query 6066 PPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVK 6125
PPG+QFKHL+PLM KG W +VR +IVQMLSDTL LSD FV WAHGFELTS YF K
Sbjct 6140 PPGEQFKHLVPLMNKGAAWPIVRRRIVQMLSDTLDKLSDYCTFVCWAHGFELTSASYFCK 6199
Query 6126 IGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLY 6185
IG E+ CC+C+RRA+ +S+ +YACW HS G+DYVYNPF +DVQQWG+ GNL +NHD Y
Sbjct 6200 IGKEQRCCMCNRRASTYSSPLHSYACWSHSSGYDYVYNPFFVDVQQWGYIGNLATNHDRY 6259
Query 6186 CQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAA 6245
C VH AHVAS DA+MTRCLA+H+CF++RV+W I YP I E ++N+ CR V+ VV+AA
Sbjct 6260 CSVHQGAHVASNDAVMTRCLAIHDCFIERVEWDITYPYISHEKRLNSCCRAVERNVVRAA 6319
Query 6246 LLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDG 6305
LLA +F ++DIGNPK I V V+W +YDAQP S K+++LFY+ + F+DG
Sbjct 6320 LLAGRFERVYDIGNPKGIPIVDDPVVDWHYYDAQPLS---KKVQQLFYTED-CAKNFSDG 6375
Query 6306 VCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLK 6365
+CLFWNCNV RYP N+IVCRFDTRV S NLPGCDGGSLYVNKHAFHTPA+D SAF +LK
Sbjct 6376 LCLFWNCNVPRYPNNAIVCRFDTRVHSEFNLPGCDGGSLYVNKHAFHTPAYDASAFRDLK 6435
Query 6366 QLPFFYYSDSPCESHG-KQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYN 6424
LPFFYYS +PCE HG ++ DIDYVPLKSA CIT CNLGGAVCR HA EYR Y++AYN
Sbjct 6436 PLPFFYYSTTPCEVHGNGNMLEDIDYVPLKSAVCITACNLGGAVCRKHAAEYRDYMEAYN 6495
Query 6425 MMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVY 6484
++ ++GF LW YK FD YNLW+TFT++Q LEN+A+NV+ +GHF G +GE+PV+++N+ +Y
Sbjct 6496 LVSASGFRLWCYKTFDVYNLWSTFTKIQGLENIAYNVIKQGHFTGVEGELPVAVVNDKIY 6555
Query 6485 TKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDA 6544
TK D DV +FENKTTLP N+AFEL+AKR ++ P+ +L NL VD+ V+WDY+R
Sbjct 6556 TKSDVNDVCIFENKTTLPTNIAFELYAKRAVRSHPDFNLLRNLEVDVCYKFVLWDYERSN 6615
Query 6545 PAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQ 6604
+TIGVC TDI IC FD R +G ++ F + NG+LI++ VK
Sbjct 6616 IYGSATIGVCKYTDIDVNSALNIC------FDIRDNGSLERFMSLPNGILISDRKVKNYP 6669
Query 6605 PSVGPKQASLNGVTLIGEAVKTQ-----------FNYYKKVDGVVQQLPETYFTQSRNLQ 6653
V A NG + +Q F YKKV+ Q +TY+T R +
Sbjct 6670 CIVSSNYAYFNGTLIRDNTGNSQSSDGEVKQPVTFYIYKKVNNEFVQFTDTYYTLGRTVS 6729
Query 6654 EFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKES 6713
+F P S+ME DFL L D FI++YKLE YAFEH+VYGDFS + LGGLHLLIGL K+ +E
Sbjct 6730 DFTPVSEMEKDFLALDSDVFIKKYKLEAYAFEHVVYGDFSRTTLGGLHLLIGLYKKHQEG 6789
Query 6714 PFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVT 6773
+E+ + +TV NYF+T++ T S K VCSVIDL LDDFV+IIK+ DLSVVSKVVK+
Sbjct 6790 HIIMEEMLKERATVHNYFVTESNTASFKAVCSVIDLKLDDFVDIIKAMDLSVVSKVVKIP 6849
Query 6774 IDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSAT 6833
ID T I FMLWCKDG V+TFYP+LQ+ W+PG+AMP+L+K+Q LE C L NY S
Sbjct 6850 IDLTMIEFMLWCKDGQVQTFYPRLQAINDWKPGLAMPSLFKVQNSNLEPCMLPNYKQSIP 6909
Query 6834 LPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL 6893
+P+G+ MN+AKY QLCQYLNT T+AVP NMRV+HFGAGSDKGVAPG++VLRQWLPT +L
Sbjct 6910 MPQGVHMNIAKYMQLCQYLNTCTIAVPANMRVMHFGAGSDKGVAPGSSVLRQWLPTDAIL 6969
Query 6894 VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICG 6953
+D+DLN++VSDAD TL GDC TV + DL+ISDMYDP TK V + N++K FF Y+C
Sbjct 6970 IDNDLNEYVSDADITLFGDCVTVRVGQQVDLLISDMYDPSTKVVGETNEAKALFFVYLCN 7029
Query 6954 FIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKP 7013
FI+ LALGGSVAIKITEHSW+A+LY+LMG FAWWT F TN NASSSE FLIG NYLG+
Sbjct 7030 FIKNNLALGGSVAIKITEHSWSAELYELMGRFAWWTVFCTNANASSSEGFLIGINYLGEL 7089
Query 7014 REQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLL 7073
+E IDG VMHANYIFWRNT + LS+YSLFD+S+FPLKL+GT V+ LKE QIN++++SLL
Sbjct 7090 KEVIDGNVMHANYIFWRNTTLMNLSTYSLFDLSRFPLKLKGTPVLQLKESQINELVISLL 7149
Query 7074 SKGRLIIRENNRVVISSDVLVN 7095
S+G+LIIR+N+ + +S+DVLVN
Sbjct 7150 SQGKLIIRDNDTLSVSTDVLVN 7171
>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930
Score = 8670 bits (22497), Expect = 0.0, Method: Composition-based stats.
Identities = 3370/7157 (47%), Positives = 4487/7157 (63%), Gaps = 371/7157 (5%)
Query 28 VRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV--LPQLEQPYVFIKRSDARTAPHG-HV 84
V G+ +EE L A+Q L+ LV V + P + V I S G
Sbjct 29 VTGWDIPIEEALEYAKQQLRTPEPQLVFVPYYLSHAPGISGDRVVITDSIWYATNFGWQP 88
Query 85 MVELVAELEGIQYGRSGETLGVLVPH------VGEIPVAYRKVLLRKNGNKGAGGHSYGA 138
+ EL + +G++YGR G T GVL+P +G+I + RK G G +S
Sbjct 89 IRELAMDKDGVRYGRGG-THGVLLPMQDPSFIMGDIDIQIRKY--------GIGANSPPD 139
Query 139 DLKSFDLGDELGTD--PYEDFQENW-NTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
L +D + G D PY DF +N TK + ++ D +G
Sbjct 140 VLPLWDGFSDPGPDVGPYLDFPDNCCPTKPKAKRGGDVYLS----------DQYGFDNNG 189
Query 196 YPLECIKDLLARAGKASCTLSEQLDFIDTKR--GVYCCREHEHEIAWYTERSEKSYELQT 253
+E + LL K+ TL + L + R Y + ++A R Q+
Sbjct 190 ILVEPVMKLLGVI-KSDFTLEQLLAALGKYRTEDGYDLPDGYVKVAIKVGRKAVPVLKQS 248
Query 254 PFEIKLAKKFDTFNGECPNFVFPLN--SIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNE 311
F + P + +P + S+++ +P + S+Y N
Sbjct 249 IFTV-----VGVTEQLVPGYYYPFSTSSVVEHTKPTRGGPVGKTVEAVMLSLYG---TNN 300
Query 312 CNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCP 371
N +KC +C W + CG E + ++C V+K P
Sbjct 301 YNPATPVARLKCSYCDYYGWTPLKDIGTVNCLCGAEF---QLTSSCVDAESAGVIK---P 354
Query 372 ACHNSEVGPEHSLAEYHNESGLKTILRKGGRT-IAFGGCVFSYVGCHNKCAYWVPRASAN 430
C + G++ I G RT ++FGG ++S +G N WVPRA +
Sbjct 355 GC----------VMLLDKSPGMRLI--PGNRTYVSFGGAIWSPIGKVNGVTVWVPRAYSI 402
Query 431 IGCNHTGVVGEG-SEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASFSASTSA--- 486
+ H+G VG G + +N L+E L + I + D N A +A+ T A
Sbjct 403 VAGEHSGAVGSGDTVAINKELVEYLIE---GIRVDADTLDNPTCATFIANLDCDTKAPVV 459
Query 487 -FVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVR 545
VE+++GL C K+ G E + L A+ + A
Sbjct 460 HTVESLQGL-----------CLANKIMLGDKP---LPTDEFHPFIVGL-AYHVQRACWYG 504
Query 546 SIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGV 605
++ SRT E ++ VR ++ +Q+ ++ + N V +AY TG V
Sbjct 505 ALASRTFEAFRDFVRTEEER-------FAQFFGKVCAPI--------NGCVYLAYTTGRV 549
Query 606 VQLTSQWLTN------------IFGTVYEKLKPVLDWLEEKFKEGVEFLRDGW----EIV 649
++ + N + V + LKP+L+W+ +K + + W E +
Sbjct 550 TLFSAYQVLNTAIAKSKDAFGGVAAIVVDMLKPILEWVLKK----MSIAKGAWLPYAEGL 605
Query 650 KFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETF 709
+ +V G+ + + L+ ++ S+ G K+ AL G +
Sbjct 606 LALFKAQFTVVKGKFQFLRASLNSKCHSLCDLLTTIMSKLLTSVKWAGCKVDALYTGTYY 665
Query 710 VTHSKGLYRKCVKSREETGLLM-PLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQ 768
KG+ + + GLL+ P + E+ L+G+ LT+ L+ + + +
Sbjct 666 YFSRKGVLTEVQLCAKRLGLLLTPKQQKMEVEVLDGDFDAPVTLTD---LELEECTGVLE 722
Query 769 PTSEAVEAPLV-GTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGD 827
A + LV GT V + + + +D Y + V F L+GG +KVTFGD
Sbjct 723 EVFGASDVKLVKGTLVSLASKLFVRTEDGFLY-RYVKSGGVLGKAFRLRGGGVSKVTFGD 781
Query 828 DTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQP-- 885
+ V + +VN ++++ E +D +L++ + + VE GT++ + ACVV AV + L
Sbjct 782 EEVHTIPNTVTVNFSYDVCEGLDAILDKVMAPFQVEEGTKLEDLACVVQKAVYERLSDLF 841
Query 886 --VSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYP--PDEDEEEGDCEEEEF 941
L P I+L+++ + +++ + E L MY S P +DE D E+
Sbjct 842 SDCPAELRP--INLEDFLTSECFVYSKDYEKILMPEMYFSLEDAVPVDDEMVDDIED--- 896
Query 942 EPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTT 1001
++ + ++ WL D +G+ED
Sbjct 897 --------------------------TVEQASDSDDQWLGD---------EGAEDCD--- 918
Query 1002 IQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAA 1061
TI +V M GY K+ ++VYIK ADIV+EA+ V+VNAA
Sbjct 919 -NTIQDVDVATSMTTP-----------CGYTKIAEHVYIKCADIVQEARNYSYAVLVNAA 966
Query 1062 NVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKH-CLHVVGP 1120
NV L HGGGVAGALN+ATNNAMQ ES +YI NG L+ GG +LS H LA H LHVVGP
Sbjct 967 NVNLHHGGGVAGALNRATNNAMQKESSEYIKANGSLQPGGHVLLSSHGLASHGILHVVGP 1026
Query 1121 NVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDK 1180
+ G+D+ LL + Y + + +L PL+SAGIFG SL V V Y+ V+D+
Sbjct 1027 DKRLGQDLALLDAVYAAYTGFDSVLTPLVSAGIFGFTVEESLCSLVKNVACTTYVVVYDR 1086
Query 1181 NLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDK--KIKACVEE 1238
LY++ +++ ++ + Q + I E E + S+ + + +
Sbjct 1087 QLYERALATSFDVPGPQSSVQHVPAIDWAEA----VEVQESIVDQVETPSLGAVDTVDSN 1142
Query 1239 VTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTA 1298
+ L ET EN++ + PD + D V D+V++ V
Sbjct 1143 ADSGLNETARSPENVVGSV-------PDD-----------VVADVESCVRDLVRQVV--- 1181
Query 1299 VVIPTKKAGGTTEMLAKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPS 1358
+KV D P + TVE+ + +L
Sbjct 1182 -------------------KKVKRDK----RPPPIVPQQTVEQQPQEISSPGDCNTVLVD 1218
Query 1359 IISNEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDY 1418
+ VS + M+ +E L+PV ++ A + ++R +EG+
Sbjct 1219 V-----------VSMSFSAMVNFGKEKGLLIPVVIDYPAFLKVLKR----FSPKEGLFSS 1263
Query 1419 -GARFYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSV 1477
G FY Y+ + + LN L L+ +P G++ +G L +A MR L VP TV V
Sbjct 1264 NGYEFYGYSRDKPLHEVSKDLNSLGRPLIMIPFGFIVNGQTLAVSAVSMRGLTVPHTVVV 1323
Query 1478 SSPDAVTAYNGYLT---SSSKTPEEHFIETISLAGSYKDWSYSGQSTQLGIE----FLKR 1530
S +V Y Y S T + F+ I L G+ +DW + + + KR
Sbjct 1324 PSESSVPLYRAYFNGVFSGDTTAVQDFVVDILLNGA-RDWDVLQTTCTVDRKVYKTICKR 1382
Query 1531 GDKSVYYTSNPTTFHLDGEV-ITFDNLKTLLSLREVRT------IKVFTTVDNINLHTQV 1583
G+ + + + + + G+V + F + + E + IKV TTVD IN T +
Sbjct 1383 GNTYLCF-DDTNLYAITGDVVLKFATVSKARAYLETKLCAPEPLIKVLTTVDGINYSTVL 1441
Query 1584 VDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAF-EYYHTTDPSF 1642
V + +Y Q G + DG D + P + EG Y N + V A EYY D +
Sbjct 1442 VSTAQSYRAQIGTVFCDGHDWSNKNPMPTDEGTHLYKQDNFSSAEVTAIREYYGVDDSNI 1501
Query 1643 LGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRA 1702
+ R MS + W Y V+G + D+NCYL A+ LQ I++ F+ P + AY
Sbjct 1502 IARAMSIRKTVQTWPYTVVDGRVLLAQRDSNCYLNVAISLLQDIDVSFSTPWVCRAYDAL 1561
Query 1703 RAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTL 1762
+ G +++A T G D +S + H + + +RV+ VC+ CG Q
Sbjct 1562 KGGNPLPMAEVLIALGKATPGVSDDAHMVLSAVLNHGTV-TARRVMQTVCEHCGVSQMVF 1620
Query 1763 KGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYEL-KHGTF 1821
G +A + G++ + V + C CG+ A +Y+ +Q+SP+++MS P Q L G +
Sbjct 1621 TGTDACTFYGSVVLDDLYAPVSVVCQCGRPAIRYVSEQKSPWLLMSCTPTQVPLDTSGIW 1680
Query 1822 TCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVT 1881
A + G GHY + + + D ++S+ K P TD+ Y S+T+ K T
Sbjct 1681 KTAIVFRGPVTAGHYMYAVNGTLISVYDANTRRRTSDLKLPATDILYGPTSFTSDSKVET 1740
Query 1882 YKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPNASFDNFKFV-CDNIKFADD 1940
Y LDGV T IDP Y K+ + YFT PI++V P S+D F C N + A+
Sbjct 1741 YYLDGVKRTTIDPDFSKYVKRGDYYFTTAPIEVV-AAPKLVTSYDGFYLSSCQNPQLAES 1799
Query 1941 LNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNK 2000
N+ K +L +T +P++ GDVVAI + G+ + KP+++
Sbjct 1800 FNKAINATKTGPMKL-LTMYPNVAGDVVAISDDNVVA-HPYGSLHMGKPVLF-------- 1849
Query 2001 ATYKPNTWC-IRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENP-TIQ 2058
+PNTW + L ST V T N++DVL D PV+ E E P +++
Sbjct 1850 -VTRPNTWKKLVPLLSTVVVNTPNTYDVLAV------------DPLPVNNETSEEPISVK 1896
Query 2059 KDVLECNVKTTEVVGDIILKPANNS-LKITEEVGHTDLMAAYVDN-SSLTIKKPNELSRV 2116
+ +K T V+ P N L +E TDL YV+ + K + LS+V
Sbjct 1897 APIPLYGLKATMVLNGTTYVPGNKGHLLCLKEFTLTDLQTFYVEGVQPFVLLKASHLSKV 1956
Query 2117 LGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT--NIVTRCLNRV---------- 2164
LGL+ + VN + + YA L V+T+ +VTR + +
Sbjct 1957 LGLRV--SDSSLHVNHLSKGVVYAYAATRLTTRVTTSLLGGLVTRSVRKTADFVRSTNPG 2014
Query 2165 --CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPN 2222
C + F+ L ++ + +K S IA NT V L + + +
Sbjct 2015 SKCVGLLCLFYQLFMRFWLLVKKP-PIVKVS--GIIAYNTGCGVTTCVLNYLRSRCGNIS 2071
Query 2223 FSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYRE--GYLNSTNVTIAT 2280
+S+L+ ++ + L + L GV +S PS T ++ G + + +
Sbjct 2072 WSRLLKLLRYMLYIWFVWTCLT----ICGVWLSEPYAPSLVTRFKYFLGIVMPCDYVLVN 2127
Query 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
+C++G+DSLD YP+L Q S ++ T ++ E F AY+L+T +
Sbjct 2128 ETGTGWLHHLCMAGMDSLD-YPALRMQQHRYGSP-YNYTYILMLLEAFFAYLLYTPALPI 2185
Query 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
+G+ A++ L Y + + NSWL+ + ++++ P ++M+RMYI A + +K ++HV
Sbjct 2186 VGILAVLHLIVLYLPIP-LGNSWLVVFLYYIIRLVPFTSMLRMYIVIAFLWLCYKGFLHV 2244
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GCN+ C+MCYK+N A R+EC+T+VNGV+R FYV ANGG FC HNWNCV+CDT+
Sbjct 2245 RYGCNNVACLMCYKKNVAKRIECSTVVNGVKRMFYVNANGGTHFCTKHNWNCVSCDTYTV 2304
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
STFI +VA DLS QFKRPI TD++ Y V SV V+NG ++ YF+ GQ++YER +
Sbjct 2305 DSTFICRQVALDLSAQFKRPIIHTDEAYYEVTSVEVRNGYVYCYFESDGQRSYERFPMDA 2364
Query 2521 FVNLDNLRANNTKGSLP-INVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSD 2579
F N+ L + KG+ P NV+VFD ++ EE++ K+A++YY+QL C+PILL+D+ +V
Sbjct 2365 FTNVSKLHYSELKGAAPAFNVLVFDATNRIEENAVKTAAIYYAQLACKPILLVDKRMVGV 2424
Query 2580 VGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQ 2639
VGD A +A MF+AY + +++ M+K+K L +TA +++ +++++VL F+ + R
Sbjct 2425 VGDDATIARAMFEAYAQNYLLKYSIAMDKVKHLYSTALQQISSGMTVESVLKVFVGSTRA 2484
Query 2640 GFVD--SDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSAR 2697
D SDV+T D+V C++L HQ E T DS NN + TY K + ++ ++G + +A+
Sbjct 2485 EAKDLESDVDTNDLVSCIRLCHQEGWEWTTDSWNNLVPTYIKQDTLSTLEVGQFMTANAK 2544
Query 2698 HINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTK 2757
++NA +AK + LIW DF+ LSE +R+Q++ AA+K L +T ++ + V + T
Sbjct 2545 YVNANIAKGAAVNLIWRYADFIKLSESMRRQLKVAARKTGLNLLVTTSSLKADVPCMVTP 2604
Query 2758 IALKGG-KIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGV 2816
+ GG + + +W + LI V ++ + + ++ TP ++M ++ +K ID V
Sbjct 2605 FKIIGGHRRIVSWRRVLIHVFMLLVVLNPQWF--TPWYIMRP---IEYNVVDFKVIDNAV 2659
Query 2817 TRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRT 2876
RDI S D CFANK + F+ W+S R GSY N + CP++ V++ VG +VPGLP LR
Sbjct 2660 IRDITSADQCFANKFSAFENWYSNRYGSYVNSRGCPMVVGVVSDIVGSLVPGLPARFLRV 2719
Query 2877 TNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDT 2936
L + AVG++CYTP I Y F TSACVLAA CT+F ASG+ +PYC D
Sbjct 2720 GT-TLLPLVNYGLGAVGSVCYTPHYAINYDVFDTSACVLAATCTLFSSASGERMPYCADA 2778
Query 2937 NVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAG 2995
+++ + Y+ L+P Y + S I+FP V +V T EYC+ G C+ SEAG
Sbjct 2779 ALIQNASRYDMLKPHVMYPFYEHSGYIRFPEVIS-AGVHIVRTMAMEYCKVGRCDVSEAG 2837
Query 2996 VCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAI 3055
+C+S RWV+NN Y+R GV+CG A +L NM P+ P+GA+DI+ SI+ G ++A+
Sbjct 2838 LCMSLQPRWVVNNAYFRQQSGVYCGTSAFDLFMNMLLPIFTPVGAVDITTSILMGALLAV 2897
Query 3056 VVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFY 3115
VV+ YY +RFRRAFG+YS V+ N L F+++ VLCL Y LP +Y++++LY T Y
Sbjct 2898 VVSMSLYYLLRFRRAFGDYSGVIFTNILAFVLNVIVLCLEGPYPMLPSIYAMVFLYATCY 2957
Query 3116 LTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTF 3175
+D++ + H+ +++MF +VP W+T+ YI+ + ++H WF S KR V ++F +F
Sbjct 2958 FGSDIACMMHVSFLIMFAGVVPLWVTVLYIVVVLSRHILWFASLCTKRTVQVGDLAFHSF 3017
Query 3176 EEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLA 3235
++AAL TF+L+KE++L+L+ ++ Y +YLA+YNKYKY+SG MDT +YREAAC HL
Sbjct 3018 QDAALQTFMLDKEVFLRLKREI--SSDAYFKYLAMYNKYKYYSGPMDTAAYREAACSHLV 3075
Query 3236 KALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
AL +SN G D +YQPP+ S+ SA LQ+G +MA PSG VE C+V+V G+ TLNG+WL
Sbjct 3076 MALEKYSNGGGDTIYQPPRCSVASAALQAGLTRMAHPSGLVEPCLVKVNYGSMTLNGIWL 3135
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVD 3355
D+ V CPRHV+C+ +++ NP+Y L +R +N++F V +RVIGH+M+ +LKL VD
Sbjct 3136 DNFVICPRHVMCSRDELANPDYPRLSMRAANYDFHVSQNGHNIRVIGHTMEGSLLKLTVD 3195
Query 3356 TANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNI 3415
NPKTP Y F+R+ GQ S+LACY+G P+GVY C +R N T++ SFL GSCGS GF +
Sbjct 3196 VNNPKTPAYSFIRVSTGQAMSLLACYDGLPTGVYTCTLRSNGTMRASFLCGSCGSPGFVM 3255
Query 3416 DYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAV 3475
+ V FCY+H +ELP G H GTD G FYGPF D+Q Q A D TITVNVLAWLYAAV
Sbjct 3256 NGKEVQFCYLHQLELPNGTHTGTDFSGVFYGPFEDKQVPQLAAPDCTITVNVLAWLYAAV 3315
Query 3476 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL 3535
++G+ WFL + + + +FN A+KY + +T + + +L PL+A+TGI+V M ++LK LL
Sbjct 3316 LSGENWFLTKSSISPAEFNNCAVKYMCQSVTSESLQVLQPLAAKTGISVERMLSALKVLL 3375
Query 3536 QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLV 3595
G GRTI+GS LEDE TP+D+ RQ GV Q + + T W + + ++L+L+
Sbjct 3376 SAGFCGRTIMGSCSLEDEHTPYDIGRQMLGVKLQGKFQSMFRWTLQWFAIIFVLTILILL 3435
Query 3596 QSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYM 3655
Q QW+ L LP + F + +KHKH +L ++LLP AY+N Y
Sbjct 3436 QLAQWTFVGALPFTLLLPLIGFVAVCVGFVSLLIKHKHTYLTVYLLPVAMVTAYYNFQYT 3495
Query 3656 PASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVL 3715
P +++ + V+ D + V L++ R V D R+W + +
Sbjct 3496 PEGVQGYLLSLYNYVNPGRIDVIGTDLLTMLIISVACTLLSVRMVRTDAYSRIWYVCTAV 3555
Query 3716 TLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNT 3775
+Y + G+A AIS ++SV +NY+GV ++ A+ +V++ P +
Sbjct 3556 GWLYNCWTGSADTVAISYLTFMVSVFTNYTGVACASLYAAQFMVWVLKFLDPTILLLYGR 3615
Query 3776 LQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSI 3835
+C+++ Y +GY CTCYFG+F L+NR FR TLG Y+Y+VS+QE RYMNS GLLPP NS
Sbjct 3616 FRCVLVCYLLVGYLCTCYFGVFNLINRLFRCTLGNYEYVVSSQELRYMNSHGLLPPTNSW 3675
Query 3836 DAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLH 3895
A LNIKL G+GG P +V+T+QS M+D+KCTSVVLLSVLQQLRVESSSKLWA CV+LH
Sbjct 3676 QALMLNIKLAGIGGIPIYRVSTIQSNMTDLKCTSVVLLSVLQQLRVESSSKLWALCVKLH 3735
Query 3896 NDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYA 3955
N+IL + TEAFE VSLLSVLLS+ GA+++++LC +L+N + LQA+ASEFS+L SY
Sbjct 3736 NEILASNSPTEAFEAFVSLLSVLLSLPGAINLDELCSSILENNSVLQAVASEFSNLSSYV 3795
Query 3956 AFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQ 4015
+ AQ+AY+ AVA G + LKK++NVAKS D+D A RKLE+M++ AMT MYKQ
Sbjct 3796 DYENAQKAYDTAVATGAPASTVNALKKAMNVAKSVLDKDVATTRKLERMSELAMTAMYKQ 3855
Query 4016 ARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIP 4075
AR+ED+R+KVT+AMQTMLF M+R+LD+DAL+NI+NNAR+G VPL +IP T A KL++V+P
Sbjct 3856 ARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILNNARNGVVPLGVIPRTAANKLLLVVP 3915
Query 4076 DYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALR--A 4133
D++ Y T T TYA + W++ QV DAD K V ++I+ +NS NLAWPL+VTA R A
Sbjct 3916 DFSVYTATITMPTLTYAGSAWDVMQVADADGKTVNATDITRENSVNLAWPLVVTAQRQQA 3975
Query 4134 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKW 4193
S VKLQNNEL P +++M+ AG +QTAC D A+AYYN TK GR V+A+L+D L +
Sbjct 3976 TSPVKLQNNELMPQTVKRMNVVAGVSQTACVTD-AVAYYNATKEGRHVMAILADTDGLAF 4034
Query 4194 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4253
A+ KS G G + ELEPPC+F+ DTPKGP +KYLYF KGL NL RG VLG+LA TVRL
Sbjct 4035 AKVEKSTGDGFVILELEPPCKFMVDTPKGPALKYLYFTKGLKNLCRGTVLGTLACTVRLH 4094
Query 4254 AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
AG+ATEV +NS++LS C+F+VD YKDYL +GG PI NCVKML HTGTG AIT P+
Sbjct 4095 AGSATEVASNSSILSLCSFSVDPEATYKDYLDNGGSPIGNCVKMLTPHTGTGLAITAKPD 4154
Query 4314 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVC 4373
AN+DQESFGGASCCLYCRCHI+HP G C KGK+VQIP NDP+GF ++N VC VC
Sbjct 4155 ANIDQESFGGASCCLYCRCHIEHPGASGVCKYKGKFVQIPLVGVNDPIGFCIRNVVCAVC 4214
Query 4374 GMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYND 4432
MW+GYGC C LRE LQ+ D + FLNRV G S ARL P G+G D+V RAFDI N
Sbjct 4215 NMWQGYGCPCSSLREINLQARD-ECFLNRVRGTSGVARLVPLGSGVQPDIVLRAFDICNT 4273
Query 4433 KVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHD 4492
KVAGF LK NCCR+QE D D +DSYFVVKRHT SNY E+ Y LKDC VA+HD
Sbjct 4274 KVAGFGLHLKNNCCRYQELDADGTQLDSYFVVKRHTESNYLLEQRCYEKLKDCGVVARHD 4333
Query 4493 FFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKK 4552
FFKF I+G M PH+SR+RLTKYTMADLVY+LRHFD NCDTLKEILV CC DYF++K
Sbjct 4334 FFKFNIEGVMTPHVSRERLTKYTMADLVYSLRHFDNNNCDTLKEILVLRGCCTADYFDRK 4393
Query 4553 DWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFG 4612
DWYD VENPDI+RVY NLGE VR+A+L V+ D+M G++GVLTLDNQDLNG WYDFG
Sbjct 4394 DWYDPVENPDIIRVYHNLGETVRKAVLSAVKMADSMVEQGLIGVLTLDNQDLNGQWYDFG 4453
Query 4613 DFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERL 4672
DFI+ G+GV V+D+YYSL MP+ T+T L AE HVD D +KP WD+ KYD+T+ +
Sbjct 4454 DFIEGPAGAGVAVMDTYYSLAMPVYTMTNMLAAECHVDGDFSKPKRVWDICKYDYTQFKY 4513
Query 4673 KLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPF 4732
LF +YFKYWD YHPNCV C DDRCILHCANFN+LFS V P TSFGPLV+KI+VDGVPF
Sbjct 4514 SLFSKYFKYWDMQYHPNCVACADDRCILHCANFNILFSMVLPNTSFGPLVQKIYVDGVPF 4573
Query 4733 VVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAA 4792
VVSTGYH+RELGVV NQD+ H+ RLS +ELLVYAADPAMH A+ N L DKRT C SVAA
Sbjct 4574 VVSTGYHYRELGVVMNQDIRQHAQRLSLRELLVYAADPAMHVAASNALADKRTVCMSVAA 4633
Query 4793 LTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNL 4852
+T V FQTVKPG FN+DFY+FAV GFFKEGS++ KHFF+AQDGNAAISDYDYYRYNL
Sbjct 4634 MTTGVTFQTVKPGQFNEDFYNFAVKCGFFKEGSTISFKHFFYAQDGNAAISDYDYYRYNL 4693
Query 4853 PTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMS 4912
PTMCDI+QLLF +EVVDKYFDCYDGGC+ A+QV+V N DKSAGFPFNK+GKARLYY+S+S
Sbjct 4694 PTMCDIKQLLFSLEVVDKYFDCYDGGCLQASQVVVANYDKSAGFPFNKFGKARLYYESLS 4753
Query 4913 YEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIA 4972
Y DQD LFAYTKRNV+PTITQMNLKYAISAKNRARTVAGVSI STMTNRQFHQK+LKSIA
Sbjct 4754 YADQDELFAYTKRNVLPTITQMNLKYAISAKNRARTVAGVSIASTMTNRQFHQKMLKSIA 4813
Query 4973 ATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLAR 5032
A RGA+VVIGT+KFYGGW+ ML+T+ VENPHLMGWDYPKCDRAMPN+LRI ASL+LAR
Sbjct 4814 AARGASVVIGTTKFYGGWNRMLRTLCEGVENPHLMGWDYPKCDRAMPNLLRIFASLILAR 4873
Query 5033 KHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAV 5092
KH TCC+ S RFYRLANECAQVLSEMV+CGG YVKPGGTSSGD+TTAYANSVFNICQAV
Sbjct 4874 KHATCCNASERFYRLANECAQVLSEMVLCGGGFYVKPGGTSSGDSTTAYANSVFNICQAV 4933
Query 5093 TANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSD 5152
+AN+N LS DGNKI YV+ LQ RLY +YR+ VD + V ++Y YLRKHFSMMILSD
Sbjct 4934 SANLNTFLSIDGNKIYTTYVQELQRRLYLGIYRSNTVDNELVLDYYNYLRKHFSMMILSD 4993
Query 5153 DAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLV 5212
D VVC+N+ YA +G VA I+ FK +LY+QNNVFMSE+KCW E D+TKGPHEFCSQHTMLV
Sbjct 4994 DGVVCYNADYAQKGYVADIQGFKELLYFQNNVFMSESKCWVEPDITKGPHEFCSQHTMLV 5053
Query 5213 KQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADV 5272
+ VYLPYPDPSRILGAGCFVDD++KTDGTLM+ER+VSLAIDAYPLTKHP+ EY +V
Sbjct 5054 DMKGEQVYLPYPDPSRILGAGCFVDDLLKTDGTLMMERYVSLAIDAYPLTKHPDPEYQNV 5113
Query 5273 FHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLC 5332
F YLQYI+KLH+ELTGH+LD YSVML +DN S+YWE EFYE MY LQ+VG CV+C
Sbjct 5114 FWCYLQYIKKLHEELTGHLLDTYSVMLASDNASKYWEVEFYENMYMESATLQSVGTCVVC 5173
Query 5333 NSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGM 5392
NSQTSLRCG CIRRPFLCCKCCYDHV+ST+HKLVLSV PYVCN P CDV DVTQLYLGGM
Sbjct 5174 NSQTSLRCGGCIRRPFLCCKCCYDHVVSTTHKLVLSVTPYVCNNPSCDVADVTQLYLGGM 5233
Query 5393 SYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTE 5452
SYYC+ H+PPISFPLCANGQVFGLYKN C GS +V DFN++ATCDW+N+ DY+LANT TE
Sbjct 5234 SYYCRDHRPPISFPLCANGQVFGLYKNICTGSPDVADFNSLATCDWSNSKDYVLANTATE 5293
Query 5453 RLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVT 5512
RLKLFAAETL+ATEE K +Y A V+EVLSDREL LSWE GK RPPLNRNYVFTG+ +T
Sbjct 5294 RLKLFAAETLRATEENAKQAYASAVVKEVLSDRELVLSWETGKTRPPLNRNYVFTGFHIT 5353
Query 5513 KNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVR 5572
KNSKVQ+GEY FEKGDYGD V YR +TTYKL VGDYFVLTSH+V PLS+PTL+PQE Y +
Sbjct 5354 KNSKVQLGEYIFEKGDYGDVVNYRSSTTYKLQVGDYFVLTSHSVQPLSSPTLLPQERYTK 5413
Query 5573 ITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTA 5632
+ GLYP +N+ + F+SNV +YQ+VGM +Y+T+QGPPGTGKSH +IGLALYYPSA+IVYTA
Sbjct 5414 LVGLYPAMNVPESFASNVVHYQRVGMSRYTTVQGPPGTGKSHLSIGLALYYPSAKIVYTA 5473
Query 5633 CSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTA 5692
CSHAAVDALCEKA K LPI++CSRI+PA+ARVECF KFKVN QYVF T+NALPETTA
Sbjct 5474 CSHAAVDALCEKAHKNLPINRCSRIVPAKARVECFSKFKVNDVGAQYVFSTINALPETTA 5533
Query 5693 DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRL 5752
DI+V DE+SM TNYDLS++NAR+RAKH VY+GDPAQLPAPRTLLTKGTL PE+FNSVCRL
Sbjct 5534 DILVVDEVSMCTNYDLSMINARVRAKHIVYVGDPAQLPAPRTLLTKGTLAPEHFNSVCRL 5593
Query 5753 MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAI 5812
M +GPD+FL TC RCP EIVDTVSALVYD KLKA+K + +C+K +YKG +THD SSAI
Sbjct 5594 MVAVGPDIFLATCYRCPKEIVDTVSALVYDKKLKANKVTTGECYKCYYKGSVTHDSSSAI 5653
Query 5813 NRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQ 5872
N+PQ+G+V+EFL +NP W+ AVFISPYNSQN+VA ++LGL TQTVDSSQGSE+DYVI+ Q
Sbjct 5654 NKPQLGLVKEFLIKNPKWQSAVFISPYNSQNSVARRMLGLQTQTVDSSQGSEFDYVIYCQ 5713
Query 5873 TTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGL 5932
T++TAH+ NVNRFNVAITRAK GILC+MSD LY+ L+FT L++ +Q+E GL
Sbjct 5714 TSDTAHALNVNRFNVAITRAKKGILCVMSDSTLYESLEFTPLDVNDYVKPKMQSEVTVGL 5773
Query 5933 FKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRLISMMGFKMNYQV 5991
FKDC+K L P APT +SV+ KFK E LCV M Y RLIS MGFK + +
Sbjct 5774 FKDCAKAE-PLGPAYAPTFVSVNDKFKLNESLCVHFDTTELQMPYNRLISKMGFKFDLNI 5832
Query 5992 NGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVD 6051
GY +FITRE+AIR VR W+GFDVEG HA +GTNLPLQ+GFSTGVN V P+GY+D
Sbjct 5833 PGYSKLFITREQAIREVRGWVGFDVEGAHACGPNIGTNLPLQIGFSTGVNFVVTPSGYID 5892
Query 6052 TPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLW 6111
T + + + V +K PPGDQFKHLIPLM KG PW+VVR +IV+ML DTL +SD V FV W
Sbjct 5893 TESGSRLANVVSKAPPGDQFKHLIPLMRKGEPWSVVRKRIVEMLCDTLDGVSDTVTFVTW 5952
Query 6112 AHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSI---GFDYVYNPFMID 6168
AHGFELT++ YF K+GPER C +C RRAT FS+ Y+CW H G D+VYNPF++D
Sbjct 5953 AHGFELTTLHYFAKVGPERKCFMCPRRATLFSSVYGAYSCWSHHRHIGGADFVYNPFLVD 6012
Query 6169 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 6228
VQQWG+ GNLQ NHD C VH AHVASCDAIMTRCLA+H+CF V+W +EYPII +EL
Sbjct 6013 VQQWGYVGNLQVNHDNVCDVHKGAHVASCDAIMTRCLAIHDCFCGEVNWDVEYPIIANEL 6072
Query 6229 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 6288
IN ACR VQ +V+KAA+ A ++DIGNPKAIK W FYD P +
Sbjct 6073 AINRACRSVQRVVLKAAVKALHIETIYDIGNPKAIKVYGVNVNNWNFYDTNPV---VEGV 6129
Query 6289 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 6348
++L Y Y H D+F DG+ +FWNCNVD YP N++VCRFDTRVLS LNL GC+GGSLYVN+
Sbjct 6130 KQLHYVYDVHRDQFKDGLAMFWNCNVDCYPHNALVCRFDTRVLSKLNLAGCNGGSLYVNQ 6189
Query 6349 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCES---HGKQVVSDIDYVPLKSATCITRCNLG 6405
HAFHT AF+K+AFVNLK LPFFYYSD+ CE+ VS++DYVPLKS CITRCNLG
Sbjct 6190 HAFHTDAFNKNAFVNLKPLPFFYYSDTACENATGVSTNYVSEVDYVPLKSNVCITRCNLG 6249
Query 6406 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKG 6465
GAVC+ HA+EYR +L++YN M+SAGF+LWV K FD +NLW+TF +LQSLENVA+NV+ G
Sbjct 6250 GAVCKKHADEYRNFLESYNTMVSAGFTLWVDKTFDVFNLWSTFVKLQSLENVAYNVLKSG 6309
Query 6466 HFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILN 6525
HF GE+PV+I+N+ +Y K DG D LF N T LP NVAFELWAKR++ VPEVK+L
Sbjct 6310 HFTAVAGELPVAILNDRLYIKEDGADKLLFTNNTCLPTNVAFELWAKRSVNVVPEVKLLR 6369
Query 6526 NLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDL 6585
NLGV N VIWDY+ +AP +T+G+C+ TD+ K + V DGR
Sbjct 6370 NLGVTCTYNLVIWDYESNAPLVPNTVGICTYTDLTKLDDQ------VVLVDGRQLDAYSK 6423
Query 6586 FRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETY 6645
F +N + + K + + GP AS+NGV + T F Y + DG Q + Y
Sbjct 6424 FCQLKNAIYFSPSKPKCV-CTRGPTHASINGVVVEAPDRGTAFWYAMRKDGAFVQPTDGY 6482
Query 6646 FTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIG 6705
FTQSR + +F+PR+Q+EIDFL+L F+++Y L EHIVYG F + +GGLHLLIG
Sbjct 6483 FTQSRTVDDFQPRTQLEIDFLDLEQSCFLDKYDLHDLGLEHIVYGQFDGT-IGGLHLLIG 6541
Query 6706 LAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV 6765
+R + + +E + D TV +Y + D T SSK VCSV+D++LDDF+ +IK+QD SV
Sbjct 6542 AVRRKRTAHLVMETVLGTD-TVTSYAVIDQPTASSKQVCSVVDIILDDFIALIKAQDRSV 6600
Query 6766 VSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDL 6825
VSKVV+ +D+ FMLWCK G + TFYP+LQ+ Q W+PG +MP LYK+Q +LE C L
Sbjct 6601 VSKVVQCCLDFKVFRFMLWCKGGKISTFYPQLQAKQDWKPGYSMPALYKVQNAVLEPCLL 6660
Query 6826 QNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQ 6885
NYG +A LP G +MNVAKYTQLCQYLNT +LAVP MRV+HFGAGSDKGV PGTAVL+Q
Sbjct 6661 HNYGQAARLPSGTLMNVAKYTQLCQYLNTCSLAVPAKMRVMHFGAGSDKGVCPGTAVLKQ 6720
Query 6886 WLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKE 6945
WLP LVD+DL SDADST +G C T + NKWD I SDMYD +TKN + +N SKE
Sbjct 6721 WLPADAYLVDNDLCYCASDADSTYVGSCETFFSVNKWDFIFSDMYDARTKNTSGDNTSKE 6780
Query 6946 GFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLI 7005
GFFTY+ GFI+ KLALGGS+AIKITEHSW+ADLY +MGHF WWT F T+VN+SSSEAFLI
Sbjct 6781 GFFTYLTGFIRSKLALGGSIAIKITEHSWSADLYAIMGHFNWWTCFCTSVNSSSSEAFLI 6840
Query 7006 GCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQI 7065
G NY+G +DG+ MHANY+FWRN+ +QLSSYSL+D+ +FPL+L+GT VMSLKE Q+
Sbjct 6841 GVNYIGV-GALLDGWQMHANYVFWRNSTVMQLSSYSLYDLQRFPLRLKGTPVMSLKEDQL 6899
Query 7066 NDMILSLLSKGRLIIRE 7082
N+++L+L+ GRLI+R+
Sbjct 6900 NELVLNLIRAGRLIVRD 6916
>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=rep PE=1 SV=1
Length=7078
Score = 8149 bits (21144), Expect = 0.0, Method: Composition-based stats.
Identities = 3037/6090 (50%), Positives = 4026/6090 (66%), Gaps = 199/6090 (3%)
Query 1156 ADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPF- 1214
+V + + + ++V E ++ + +++A + + + +
Sbjct 1034 VPVEDIAQVVIADTLQETPVVSDTVEVPPQVVKLPSEPQTIQPEVKEVAPVYEADTEQTQ 1093
Query 1215 -ITESKPSVEQRKQDDK----KIKACVEEVT----TTLEETKFLTENLLLYI-------- 1257
+T + +++ D + K E VT ++ K E++L+
Sbjct 1094 SVTVKPKRLRKKRNVDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHG 1153
Query 1258 -DINGNLHPDSATLVSDIDITFLKKDAPYIVGD-VVQEGVLTA-----VVIPTKKAGGTT 1310
I G ++ S V ++ P VGD V+ +G A VV P +A
Sbjct 1154 GGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDV 1213
Query 1311 EMLAK---ALRKVPTDNYITTYPGQGLNG--------YTVEEAKTVLKKCKSAFYILPSI 1359
+L+K A+ P +T G+ G Y + EAKT + ++ + S+
Sbjct 1214 SLLSKCYKAMNAYPL--VVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSL 1271
Query 1360 ISNEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYG 1419
+ + L LR + A++ + VC + A ++ K + VD G
Sbjct 1272 TIVDIPQSLTFSYDGLRGAIRKAKDYGFTVFVCTDNSANTKVLRNKGVDYTKKFLTVD-G 1330
Query 1420 ARFYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSS 1479
++Y YTSK T+ ++ N + +++MPLGYV+HGL+L +A +R + VP +++
Sbjct 1331 VQYYCYTSKDTLDDILQQANK-SVGIISMPLGYVSHGLDLIQAGSVVRRVNVPYVCLLAN 1389
Query 1480 PDAVTAYNGYLTSSSK--TPEEHFIETISLAGSYKDWSYSG-----QSTQLGIEFLKRGD 1532
+ L S P E FI+ + G Y W Q +L + L D
Sbjct 1390 KEQ----EAILMSEDVKLNPSEDFIKHVRTNGGYNSWHLVEGELLVQDLRLN-KLLHWSD 1444
Query 1533 KSVYYTSNPTTFHLDGEVITFDNLKTLLSLREVRT-----IKVFTTVDNINLHTQVVDMS 1587
+++ Y + + F+ L + + RT I+V TVD +N T V++
Sbjct 1445 QTICYKDSVFYVVKNSTAFPFETLSACRAYLDSRTTQQLTIEVLVTVDGVNFRTVVLNNK 1504
Query 1588 MTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAF-EYYHTTDPSFLGRY 1646
TY Q G + +GAD++ P G + Y+ N +A E Y DP+FL R+
Sbjct 1505 NTYRSQLGCVFFNGADISDTIPDEKQNGHSLYLADNLTADETKALKELYGPVDPTFLHRF 1564
Query 1647 MSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQI-ELKFNPPALQDAYYRARAG 1705
S KWK + + S+K +DNNCYL ++TL + ++KF PALQ A+ + + G
Sbjct 1565 YSLKAAVHKWKMVVCDKVRSLKLSDNNCYLNAVIMTLDLLKDIKFVIPALQHAFMKHKGG 1624
Query 1706 EAANFCALILAYCNKTVGELGDVRETMSYLFQHANLD-SCKRVLNVVCKTCGQQQTTLKG 1764
++ +F ALI+AY N T G D + + A L S + V C CG + L+G
Sbjct 1625 DSTDFIALIMAYGNCTFGAPDDASRLLHTVLAKAELCCSARMVWREWCNVCGIKDVVLQG 1684
Query 1765 VEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGT---F 1821
++A Y+G + E + + C CG + + +V+ +P++++S P + + T F
Sbjct 1685 LKACCYVGVQTVEDLRARMTYVCQCGGERHRQIVEHTTPWLLLSGTPNEKLVTTSTAPDF 1744
Query 1822 TCASEYTG-NYQCGHYKHITSKETLYC-IDGALLTKSSEYKGPITDVFYKENSYTTTIKP 1879
+ + G GHY H K L D ++K+S++K +TDV + Y++
Sbjct 1745 VAFNVFQGIETAVGHYVHARLKGGLILKFDSGTVSKTSDWKCKVTDVLFPGQKYSSDCNV 1804
Query 1880 VTYKLDGVVCTEIDPKLDNYYKKDNSYFT-EQPIDLVPNQPYPNASFDNFKFVCDNIKFA 1938
V Y LDG TE+DP L +Y KD YFT E P+ P + + N V + +
Sbjct 1805 VRYSLDGNFRTEVDPDLSAFYVKDGKYFTSEPPVTYSPATILAGSVYTNSCLVSSDGQPG 1864
Query 1939 DD-----LNQLTGYK--KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIV 1991
D N L G+ KP +++ +F P +GDV+ ++ Y P +K GA KPI+
Sbjct 1865 GDAISLSFNNLLGFDSSKPVTKKYTYSFLPKEDGDVLLAEFDTYDPIYKNGAMYKGKPIL 1924
Query 1992 WHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEV 2051
W + + K N +R ++ P+E N F L E PV
Sbjct 1925 WVNKASYDTNLNKFNRASLRQIFDVAPIELENKFTPLSVEST------------PVEPPT 1972
Query 2052 VENPTIQKD--VLECNVKTTEVV-GDIILKPANNSLKITEEVGHTDLMAAYVD-NSSLTI 2107
V+ +Q++ +++C V ++ ++ + E + DL YVD + +
Sbjct 1973 VDVVALQQEMTIVKCKGLNKPFVKDNVSFVADDSGTPVVEYLSKEDLHTLYVDPKYQVIV 2032
Query 2108 KKPNELSRVLGLKTLATHGLAAV---NSVPWDTIANYAKPFLNK----VVSTTTNIVTRC 2160
K N LS +L L T+ + + V S+ + F K T T V C
Sbjct 2033 LKDNVLSSMLRLHTVESGDINVVAASGSLTRKVKLLFRASFYFKEFATRTFTATTAVGSC 2092
Query 2161 LNRV-------------CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTT---IAKNTVK 2204
+ V C +++ F L L + ++ + +K S T + N VK
Sbjct 2093 IKSVVRHLGVTKGILTGCFSFVKMLFMLPLAYFSDSKLGTTEVKVSALKTAGVVTGNVVK 2152
Query 2205 SVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMS--------- 2255
++ S + L+ ++ + +++ V L S+ + VL S
Sbjct 2153 QCCTAAVDLSMDKLRRVDWKSTLRLLLMLCTTMVLLSSVYHLYVFNQVLSSDVMFEDAQG 2212
Query 2256 ----------NLGMPSYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDSLDTYPSL 2304
LG+ S C G Y + + + T+C S C+ CL DS+ YP+L
Sbjct 2213 LKKFYKEVRAYLGISSACDGLASAYR-ANSFDVPTFCANRSAMCNWCLISQDSITHYPAL 2271
Query 2305 ETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVH--FISNS 2362
+ +Q +S + ++ E LAY+L+T F L LA + FF+ ++ + S +
Sbjct 2272 KMVQTHLSHYVLNIDWLWFAFETGLAYMLYTSAFNWLLLAGTLHYFFAQTSIFVDWRSYN 2331
Query 2363 WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVE 2422
+ + L P++ +VRMY A + + K Y HV++GC + C++CYKRNR TRVE
Sbjct 2332 YAVSSAFWLFTHIPMAGLVRMYNLLACLWLLRKFYQHVINGCKDTACLLCYKRNRLTRVE 2391
Query 2423 CTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPIN 2482
+T+V G +R+FY+ ANGG FC+ HNWNCV+CDT G+TFI +EVA DL+ +RPIN
Sbjct 2392 ASTVVCGGKRTFYITANGGISFCRRHNWNCVDCDTAGVGNTFICEEVANDLTTALRRPIN 2451
Query 2483 PTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANN----TKGSLPI 2538
TD+S Y VDSVTVK + + + GQ YER L F NLD L+ T G
Sbjct 2452 ATDRSHYYVDSVTVKETVVQFNYRRDGQPFYERFPLCAFTNLDKLKFKEVCKTTTGIPEY 2511
Query 2539 NVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTF 2598
N I++D + +ES A+SA VYYSQ++C+ ILL+D +LV+ VGDS+E+A KMFD++VN+F
Sbjct 2512 NFIIYDSSDRGQESLARSACVYYSQVLCKSILLVDSSLVTSVGDSSEIATKMFDSFVNSF 2571
Query 2599 SSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDVETKDVVECLKL 2657
S +NV +KL+ L++TA + + + +VL+TFI AAR V+SDVET ++V+ ++
Sbjct 2572 VSLYNVTRDKLEKLISTARDGVRRGDNFHSVLTTFIDAARGPAGVESDVETNEIVDSVQY 2631
Query 2658 SHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKD 2717
+H+ DI++T +S NNY+ +Y K ++++ DLG+ IDC+A +N V ++ N A IWN
Sbjct 2632 AHKHDIQITNESYNNYVPSYVKPDSVSTSDLGSLIDCNAASVNQIVLRNSNGACIWNAAA 2691
Query 2718 FMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKI-ALKGGKIVNNWL------ 2770
+M LS+ L++QIR A +K NL F+LT + R N+++ + A K W
Sbjct 2692 YMKLSDALKRQIRIACRKCNLAFRLTTSKLRANDNILSVRFTANKIVGGAPTWFNALRDF 2751
Query 2771 --KQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFA 2828
K + T++ A + YL P M + I+ +K +D G+ RD+ D CFA
Sbjct 2752 TLKGYVLATIIVFLCAVLMYLCLPTFSMVPVEFYEDRILDFKVLDNGIIRDVNPDDKCFA 2811
Query 2829 NKHADFDTWFSQR-GGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPR 2887
NKH F W+ + GG Y N CPL AVI G +P +P T+ N + F+ R
Sbjct 2812 NKHRSFTQWYHEHVGGVYDNSITCPLTVAVIAGVAGARIPDVPTTLAWV-NNQIIFFVSR 2870
Query 2888 VFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYES 2947
VF+ G++CYTP I Y F+ S C+L +ECT+F+DA G+ PYC+D VL G+ AY
Sbjct 2871 VFANTGSVCYTPIDEIPYKSFSDSGCILPSECTMFRDAEGRMTPYCHDPTVLPGAFAYSQ 2930
Query 2948 LRPDTRYVLMDGSI-IQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVL 3006
+RP RY L DG++ I+FP E ++R+ T ++YCR G+CE ++ GVC++T+G W +
Sbjct 2931 MRPHVRYDLYDGNMFIKFPEVVFESTLRITRTLSTQYCRFGSCEYAQEGVCITTNGSWAI 2990
Query 3007 NNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMR 3066
ND++ + PGV+CG D ++++ + L QPI ++ S+V G + +T L YY +
Sbjct 2991 FNDHHLNRPGVYCGSDFIDIVRRLAVSLFQPITYFQLTTSLVLGIGLCAFLTLLFYYINK 3050
Query 3067 FRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHI 3126
+RAF +Y+ + +++ +C Y+ +Y Y TFY TN+ +F+ H+
Sbjct 3051 VKRAFADYTQCAVIAVVAAVLNSLCICFVASIPLCIVPYTALYYYATFYFTNEPAFIMHV 3110
Query 3127 QWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV--VFNGVSFSTFEEAALCTFL 3184
W +MF P+VP W+T Y + + +HF+W + + K+ V +G +F++AA F+
Sbjct 3111 SWYIMFGPIVPIWMTCVYTVAMCFRHFFWVLAYFSKKHVEVFTDGKLNCSFQDAASNIFV 3170
Query 3185 LNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS 3244
+NK+ Y LR+ L Y+R+L L+NKYKYFSGAM+T +YREAA CHLAKAL +S +
Sbjct 3171 INKDTYAALRNS--LTNDAYSRFLGLFNKYKYFSGAMETAAYREAAACHLAKALQTYSET 3228
Query 3245 GSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRH 3304
GSD+LYQPP SITS VLQSG KM+ PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRH
Sbjct 3229 GSDLLYQPPNCSITSGVLQSGLVKMSHPSGDVEACMVQVTCGSMTLNGLWLDNTVWCPRH 3288
Query 3305 VICTSEDMLNPNYEDLLIRKSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKT 3361
V+C ++ + +PNY+ LLI +NH+F VQ LRV+GH+MQ +LKL VD ANP T
Sbjct 3289 VMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVVGHAMQGTLLKLTVDVANPST 3348
Query 3362 PKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVS 3421
P Y F ++PG FSVLACYNG P+G + MRPN+TIKGSFL GSCGSVG+ + ++
Sbjct 3349 PAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCGSCGSVGYTKEGSVIN 3408
Query 3422 FCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRW 3481
FCYMH MEL G H G+ +G YG F+D+Q Q TD +VNV+AWLYAA++NG W
Sbjct 3409 FCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLYAAILNGCAW 3468
Query 3482 FLNRFTTTLNDFNLVAMKYNYE-PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
F+ T++ FN A+ + + VD+ L+ +TG+A+ + ++++L G
Sbjct 3469 FVKPNRTSVVSFNEWALANQFTEFVGTQSVDM---LAVKTGVAIEQLLYAIQQLY-TGFQ 3524
Query 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
G+ ILGS +LEDEFTP DV Q GV QS V++ GT HWL T++++ ++++Q+T++
Sbjct 3525 GKQILGSTMLEDEFTPEDVNMQIMGVVMQSGVRKVTYGTAHWLFATLVSTYVIILQATKF 3584
Query 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP---- 3656
+L+ +L+E + AF M+ VKHKH FL LFLLP + Y N+VY P
Sbjct 3585 TLWNYLFETIPTQLFPLLFVTMAFVMLLVKHKHTFLTLFLLPVAICLTYANIVYEPTTPI 3644
Query 3657 ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLT 3716
+S ++ + WL + + D +Y S ++L+++ R + L + +
Sbjct 3645 SSALIAVANWLAPTNAYMRTTH-TDIGVYISMSLVLVIVVKRLYNPSLSNFALALCSGVM 3703
Query 3717 LVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTL 3776
+Y G A I+ + ++TS+Y+ V + LA+ + Y P + +
Sbjct 3704 WLYTYSIGEA-SSPIAYLVFVTTLTSDYTITVFVTVNLAKVCTYAIFAYSPQLTLVFPEV 3762
Query 3777 QCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSID 3836
+ I+L+Y LG+ CTCYFG+F LLN R +GVYD+ VSTQEFR+M + L P+NS +
Sbjct 3763 KMILLLYTCLGFMCTCYFGVFSLLNLKLRAPMGVYDFKVSTQEFRFMTANNLTAPRNSWE 3822
Query 3837 AFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHN 3896
A LN KL+G+GG PCIKVA +QSK++D+KCTSVVLLSVLQQL +E++S+ WA CV+ HN
Sbjct 3823 AMALNFKLIGIGGTPCIKVAAMQSKLTDLKCTSVVLLSVLQQLHLEANSRAWAFCVKCHN 3882
Query 3897 DILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA 3956
DIL A D +EAFEK VSL + L++ G VD++ L ++ D + LQA SEFS L ++A
Sbjct 3883 DILAATDPSEAFEKFVSLFATLMTFSGNVDLDALASDIFDTPSVLQATLSEFSHLATFAE 3942
Query 3957 FATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQ 4015
AQ+AY++A+ +GD S VLK L+K++N+AK+ +++D A+ RKLE+MADQAMT MYKQ
Sbjct 3943 LEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKNAYEKDKAVARKLERMADQAMTSMYKQ 4002
Query 4016 ARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIP 4075
AR+EDK+AK+ SAMQTMLF M++KLDND LN II+NAR+GC+PL++IPL + KL VVIP
Sbjct 4003 ARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIPLSVIPLCASNKLRVVIP 4062
Query 4076 DYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN- 4134
D+ + + YA ALW+I + + D++IV+ S++ +D++ NL WPL++ RA+
Sbjct 4063 DFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDV-VDSNENLTWPLVLECTRAST 4121
Query 4135 SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
SAVKLQNNE+ P L+ M +AG QT C + ++LAYY +G + ++ALLSD LKWA
Sbjct 4122 SAVKLQNNEIKPSGLKTMVVSAGQEQTNC-NTSSLAYYEPVQGRKMLMALLSDNAYLKWA 4180
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
R DG ++ EL+PPC+F+ PKGP+++YLYF+K LNNL+RG VLG +AATVRLQA
Sbjct 4181 RVEGKDGFVSV--ELQPPCKFLIAGPKGPEIRYLYFVKNLNNLHRGQVLGHIAATVRLQA 4238
Query 4255 GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA 4314
G+ TE +NS+VLS F VD KAY D++ +GG P+TNCVKML TGTG AI+V PE+
Sbjct 4239 GSNTEFASNSSVLSLVNFTVDPQKAYLDFVNAGGAPLTNCVKMLTPKTGTGIAISVKPES 4298
Query 4315 NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCG 4374
DQE++GGAS CLYCR HI+HP+ G C KGK+VQIP C DPVGF L NT C VC
Sbjct 4299 TADQETYGGASVCLYCRAHIEHPDVSGVCKYKGKFVQIPAQCVRDPVGFCLSNTPCNVCQ 4358
Query 4375 MWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYN-- 4431
W GYGC+CD LR+ L + +FL RV G AR+ PC +G STDVV+RAFDI N
Sbjct 4359 YWIGYGCNCDSLRQAALPQSKDSNFLKRVRGSIVNARIEPCSSGLSTDVVFRAFDICNYK 4418
Query 4432 DKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKH 4491
KVAG K+ KTN CRF E D+ + +DSYFVVKRHT NY+ E+ Y+LL+DC AVA H
Sbjct 4419 AKVAGIGKYYKTNTCRFVELDDQGHHLDSYFVVKRHTMENYELEKHCYDLLRDCDAVAPH 4478
Query 4492 DFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNK 4551
DFF F +D PHI RQRLT+YTM DLVYALRHFD+ N + LK ILV Y CCD YF
Sbjct 4479 DFFIFDVDKVKTPHIVRQRLTEYTMMDLVYALRHFDQ-NSEVLKAILVKYGCCDVTYFEN 4537
Query 4552 KDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDF 4611
K W+DFVENP ++ VY LGERVRQA+L TV+FCD M AG+VGVLTLDNQDLNG WYDF
Sbjct 4538 KLWFDFVENPSVIGVYHKLGERVRQAILNTVKFCDHMVKAGLVGVLTLDNQDLNGKWYDF 4597
Query 4612 GDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEER 4671
GDF+ T PGSGV +VDSYYS LMP+L++T L AE+H D D KP I+W L +YDFT+ +
Sbjct 4598 GDFVITQPGSGVAIVDSYYSYLMPVLSMTDCLAAETHRDCDFNKPLIEWPLTEYDFTDYK 4657
Query 4672 LKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVP 4731
++LF++YFKYWDQTYH NCVNC DDRC+LHCANFNVLF+ P T FGP+VRKIFVDGVP
Sbjct 4658 VQLFEKYFKYWDQTYHANCVNCTDDRCVLHCANFNVLFAMTMPKTCFGPIVRKIFVDGVP 4717
Query 4732 FVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVA 4791
FVVS GYH++ELG+V N DV+LH RLS KEL++YAADPAMH AS N LD RT+CFSVA
Sbjct 4718 FVVSCGYHYKELGLVMNMDVSLHRHRLSLKELMMYAADPAMHIASSNAFLDLRTSCFSVA 4777
Query 4792 ALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYN 4851
ALT + FQTV+PGNFN+DFYDF VSKGFFKEGSSV LKHFFFAQDGNAAI+DY+YY YN
Sbjct 4778 ALTTGLTFQTVRPGNFNQDFYDFVVSKGFFKEGSSVTLKHFFFAQDGNAAITDYNYYSYN 4837
Query 4852 LPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSM 4911
LPTMCDI+Q+LF +EVV+KYF+ YDGGC+NA++V+VNNLDKSAG PFNK+GKAR+YY+SM
Sbjct 4838 LPTMCDIKQMLFCMEVVNKYFEIYDGGCLNASEVVVNNLDKSAGHPFNKFGKARVYYESM 4897
Query 4912 SYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSI 4971
SY++QD LFA TKRNVIPT+TQMNLKYAISAKNRARTVAGVSI STMTNRQ+HQK+LKS+
Sbjct 4898 SYQEQDELFAMTKRNVIPTMTQMNLKYAISAKNRARTVAGVSILSTMTNRQYHQKMLKSM 4957
Query 4972 AATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLA 5031
AATRGAT VIGT+KFYGGW MLKT+Y DV+NPHLMGWDYPKCDRAMPNM RI ASL+LA
Sbjct 4958 AATRGATCVIGTTKFYGGWDFMLKTLYKDVDNPHLMGWDYPKCDRAMPNMCRIFASLILA 5017
Query 5032 RKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQA 5091
RKH TCC+ RFYRLANECAQVLSE V+CGG YVKPGGTSSGDATTAYANSVFNI QA
Sbjct 5018 RKHGTCCTTRDRFYRLANECAQVLSEYVLCGGGYYVKPGGTSSGDATTAYANSVFNILQA 5077
Query 5092 VTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILS 5151
TANV+AL+ +GNKI DK V+++Q LY +YR+ D FV+++YA+L KHFSMMILS
Sbjct 5078 TTANVSALMGANGNKIVDKEVKDMQFDLYVNVYRSTSPDPKFVDKYYAFLNKHFSMMILS 5137
Query 5152 DDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTML 5211
DD VVC+NS YA++G +A I+NFK LYYQNNVFMSEAKCW ETDL KGPHEFCSQHT+
Sbjct 5138 DDGVVCYNSDYAAKGYIAGIQNFKETLYYQNNVFMSEAKCWVETDLKKGPHEFCSQHTLY 5197
Query 5212 VKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYAD 5271
+K GDD +LPYPDPSRIL AGCFVDDIVKTDGTLM+ERFVSLAIDAYPLTKH + EY +
Sbjct 5198 IKDGDDGYFLPYPDPSRILSAGCFVDDIVKTDGTLMVERFVSLAIDAYPLTKHEDIEYQN 5257
Query 5272 VFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVL 5331
VF +YLQYI KL+ +LTGHMLD YSVML DN++++WE FY +Y+ T LQAVG+CV+
Sbjct 5258 VFWVYLQYIEKLYKDLTGHMLDSYSVMLCGDNSAKFWEEAFYRDLYSSPTTLQAVGSCVV 5317
Query 5332 CNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGG 5391
C+SQTSLRCG CIRRPFLCCKCCYDHVI+T HK+VLSV+PYVCNAPGC V+DVT+LYLGG
Sbjct 5318 CHSQTSLRCGTCIRRPFLCCKCCYDHVIATPHKMVLSVSPYVCNAPGCGVSDVTKLYLGG 5377
Query 5392 MSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCT 5451
MSY+C H+P SFPLCANG VFGLYKN C GS ++ +FN +ATCDWT +GDY LANT T
Sbjct 5378 MSYFCVDHRPVCSFPLCANGLVFGLYKNMCTGSPSIVEFNRLATCDWTESGDYTLANTTT 5437
Query 5452 ERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRV 5511
E LKLFAAETL+ATEE K SY IAT++E++ +R+L L WE GK +PPLNRNYVFTGY +
Sbjct 5438 EPLKLFAAETLRATEEASKQSYAIATIKEIVGERQLLLVWEAGKSKPPLNRNYVFTGYHI 5497
Query 5512 TKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYV 5571
TKNSKVQ+GEY FE+ DY DAV Y+ +TTYKL VGD FVLTSH+V L+APT+V QE YV
Sbjct 5498 TKNSKVQLGEYIFERIDYSDAVSYKSSTTYKLTVGDIFVLTSHSVATLTAPTIVNQERYV 5557
Query 5572 RITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYT 5631
+ITGLYPT+ + +EF+S+VAN+QK G KY T+QGPPGTGKSHFAIGLA+YYP+AR+VYT
Sbjct 5558 KITGLYPTITVPEEFASHVANFQKSGYSKYVTVQGPPGTGKSHFAIGLAIYYPTARVVYT 5617
Query 5632 ACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETT 5691
ACSHAAVDALCEKA KYL I KCSRIIPA+ARVEC+D+FKVN T QY+F T+NALPET+
Sbjct 5618 ACSHAAVDALCEKAFKYLNIAKCSRIIPAKARVECYDRFKVNETNSQYLFSTINALPETS 5677
Query 5692 ADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCR 5751
ADI+V DE+SM TNYDLS++NAR++AKH VY+GDPAQLPAPRTLLT+GTLEPE FNSV R
Sbjct 5678 ADILVVDEVSMCTNYDLSIINARIKAKHIVYVGDPAQLPAPRTLLTRGTLEPENFNSVTR 5737
Query 5752 LMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSA 5811
LM +GPD+FL C RCP EIV TVSALVY+NKL A K+ S QCFK+ YKG +THD SSA
Sbjct 5738 LMCNLGPDIFLSMCYRCPKEIVSTVSALVYNNKLLAKKELSGQCFKILYKGNVTHDASSA 5797
Query 5812 INRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFT 5871
INRPQ+ V+ F+T NPAW KAVFISPYNSQNAVA +LGL TQTVDSSQGSEY YVIF
Sbjct 5798 INRPQLTFVKNFITANPAWSKAVFISPYNSQNAVARSMLGLTTQTVDSSQGSEYQYVIFC 5857
Query 5872 QTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTG 5931
QT +TAH+ N+NRFNVAITRA+ GILC+M+ + L++ L+FT L LQ++ VTG
Sbjct 5858 QTADTAHANNINRFNVAITRAQKGILCVMTSQALFESLEFTELSFT---NYKLQSQIVTG 5914
Query 5932 LFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQ 5990
LFKDCS+ +GL P APT++SVD K+KT + LCV++ +P ++ Y R+IS MGFK++
Sbjct 5915 LFKDCSRETSGLSPAYAPTYVSVDDKYKTSDELCVNL-NLPANVPYSRVISRMGFKLDAT 5973
Query 5991 VNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYV 6050
V GYP +FITREEA+R VR+WIGFDVEG HA+R A GTN+PLQLGFSTGVN V P G V
Sbjct 5974 VPGYPKLFITREEAVRQVRSWIGFDVEGAHASRNACGTNVPLQLGFSTGVNFVVQPVGVV 6033
Query 6051 DTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVL 6110
DT + ++A+PPPG+QFKHL+PLM+KG W +VR +IVQMLSDTL LSD FV
Sbjct 6034 DTEWGNMLTGIAARPPPGEQFKHLVPLMHKGAAWPIVRRRIVQMLSDTLDKLSDYCTFVC 6093
Query 6111 WAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQ 6170
WAHGFELTS YF KIG E+ CC+C+RRA +S+ +YACW HS G+DYVYNPF +DVQ
Sbjct 6094 WAHGFELTSASYFCKIGKEQKCCMCNRRAAAYSSPLQSYACWTHSCGYDYVYNPFFVDVQ 6153
Query 6171 QWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKI 6230
QWG+ GNL +NHD YC VH AHVAS DAIMTRCLA+H CF++RVDW IEYP I E K+
Sbjct 6154 QWGYVGNLATNHDRYCSVHQGAHVASNDAIMTRCLAIHSCFIERVDWDIEYPYISHEKKL 6213
Query 6231 NAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEE 6290
N+ CR V+ VV+AALLA F ++DIGNPK I V V+W ++DAQP + K+++
Sbjct 6214 NSCCRIVERNVVRAALLAGSFDKVYDIGNPKGIPIVDDPVVDWHYFDAQPLT---RKVQQ 6270
Query 6291 LFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHA 6350
LFY+ + +F DG+CLFWNCNV +YP N+IVCRFDTRV S NLPGCDGGSLYVNKHA
Sbjct 6271 LFYTEDM-ASRFADGLCLFWNCNVPKYPNNAIVCRFDTRVHSEFNLPGCDGGSLYVNKHA 6329
Query 6351 FHTPAFDKSAFVNLKQLPFFYYSDSPCESHG-KQVVSDIDYVPLKSATCITRCNLGGAVC 6409
FHTPA+D SAF +LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT CNLGGAVC
Sbjct 6330 FHTPAYDVSAFRDLKPLPFFYYSTTPCEVHGNGSMIEDIDYVPLKSAVCITACNLGGAVC 6389
Query 6410 RHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDG 6469
R HA EYR Y++AYN++ ++GF LW YK FD YNLW+TFT++Q LEN+AFN V +GHF G
Sbjct 6390 RKHATEYREYMEAYNLVSASGFRLWCYKTFDIYNLWSTFTKVQGLENIAFNFVKQGHFIG 6449
Query 6470 QQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGV 6529
+GE+PV+++N+ ++TK D+ +FENKTTLP N+AFEL+AKR ++ P+ K+L+NL
Sbjct 6450 VEGELPVAVVNDKIFTKSGVNDICMFENKTTLPTNIAFELYAKRAVRSHPDFKLLHNLQA 6509
Query 6530 DIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNA 6589
DI V+WDY+R +TIGVC TDI IC FD R +G ++ F +
Sbjct 6510 DICYKFVLWDYERSNIYGTATIGVCKYTDIDVNSALNIC------FDIRDNGSLEKFMST 6563
Query 6590 RNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQ---FNYYKKVDGVVQQLPETYF 6646
N + I++ +K VGP A NG + V Q F YKKV+ E +
Sbjct 6564 PNAIFISDRKIKKYPCMVGPDYAYFNGAIIRDSDVVKQPVKFYLYKKVNNEFIDPTECIY 6623
Query 6647 TQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGL 6706
TQSR+ +F P S ME DFL D FI++Y LE YAFEH+VYGDFSH+ LGGLHLLIGL
Sbjct 6624 TQSRSCSDFLPLSDMEKDFLSFDSDVFIKKYGLENYAFEHVVYGDFSHTTLGGLHLLIGL 6683
Query 6707 AKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVV 6766
K+ +E +E+ + ST+ NYFIT+ T + K VCSVIDL LDDFV I+KSQDL VV
Sbjct 6684 YKKQQEGHIIMEEMLKGSSTIHNYFITETNTAAFKAVCSVIDLKLDDFVMILKSQDLGVV 6743
Query 6767 SKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQ 6826
SKVVKV ID T I FMLWCKDG V+TFYP+LQ+S W+PG AMP+L+K+Q + LE+C+L
Sbjct 6744 SKVVKVPIDLTMIEFMLWCKDGQVQTFYPRLQASADWKPGHAMPSLFKVQNVNLERCELA 6803
Query 6827 NYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQW 6886
NY S +P+G+ MN+AKY QLCQYLNT TLAVP NMRVIHFGAGSDKG+APGT+VLRQW
Sbjct 6804 NYKQSIPMPRGVHMNIAKYMQLCQYLNTCTLAVPANMRVIHFGAGSDKGIAPGTSVLRQW 6863
Query 6887 LPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEG 6946
LPT +++D+DLN+FVSDAD TL GDC TV + DL+ISDMYDP TKNVT N+SK
Sbjct 6864 LPTDAIIIDNDLNEFVSDADITLFGDCVTVRVGQQVDLVISDMYDPTTKNVTGSNESKAL 6923
Query 6947 FFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIG 7006
FFTY+C I LALGGSVAIKITEHSW+ +LY+LMG FAWWT F TN NASSSE FL+G
Sbjct 6924 FFTYLCNLINNNLALGGSVAIKITEHSWSVELYELMGKFAWWTVFCTNANASSSEGFLLG 6983
Query 7007 CNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQIN 7066
NYLG +E IDG MHANYIFWRN+ P+ LS+YSLFD+SKF LKL+GT V+ LKE QIN
Sbjct 6984 INYLGTIKENIDGGAMHANYIFWRNSTPMNLSTYSLFDLSKFQLKLKGTPVLQLKESQIN 7043
Query 7067 DMILSLLSKGRLIIRENNRVVISSDVLVNN 7096
++++SLLS+G+L+IR+N+ + +S+DVLVN
Sbjct 7044 ELVISLLSQGKLLIRDNDTLSVSTDVLVNT 7073
Score = 935 bits (2417), Expect = 0.0, Method: Composition-based stats.
Identities = 298/1276 (23%), Positives = 527/1276 (41%), Gaps = 130/1276 (10%)
Query 11 KTHVQLSLPVLQVRDV---LVRGFGDSVEEVLSEARQHLKDGTCGLVEVEK--GVLPQLE 65
+ HV L++P+ ++ L F D E + L L + G L
Sbjct 26 QDHVSLTVPLCGSGNLVEKLSPWFMDG-ENAYEVVKAMLLKKEPLLYVPIRLAGHTRHLP 84
Query 66 QPYVFIKRSDARTAPHGHVMVELVAELEG-----IQYGRSGETLGVLVPHVGEIPVAYRK 120
P V++ MV +A + G+ +G+ P+ E+ +
Sbjct 85 GPRVYLVERLIACEN--PFMVNQLAYSSSANGSLVGTTLQGKPIGMFFPYDIELVTGKQN 142
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
+LLRK G GG+ Y ++ + + +DF+ + K+ + L+++L GG
Sbjct 143 ILLRKYGR---GGYHYTP--FHYERDNTSCPEWMDDFEADPKGKY----AQNLLKKLIGG 193
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCT-LSEQLDFIDTKRGVYCCREHEHEIA 239
T VD CG DG P+ L+A+ G + + G + + + +
Sbjct 194 DVTP-VDQYMCGVDGKPISAYAFLMAKDGITKLADVEADVAARADDEGFITLKNNLYRLV 252
Query 240 WYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGR 299
W+ ER + Y Q+ F I + D P F L I T+ PR + + +
Sbjct 253 WHVERKDVPYPKQSIFTINSVVQKDGVENTPP-HYFTLGCKILTLTPRNKWSGVSDLSLK 311
Query 300 IRSVYPVAS---PNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKE-GAT 355
+ +Y + S ++C CG SW TG+ ++ CG +
Sbjct 312 QKLLYTFYGKESLENPTYIYHSAFIECGSCGNDSWLTGNAIQGFACGCGASYTANDVEVQ 371
Query 356 TCGYLPQNAVVKIYCPACHNSEVG--PEHSLAEYHNESG--LKTILRKGGRTIAFGGCVF 411
+ G + NA++ CP +HS+A+ + I T+ FGG +
Sbjct 372 SSGMIKPNALLCATCPFAKGDSCSSNCKHSVAQLVSYLSERCNVIADSKSFTLIFGGVAY 431
Query 412 SYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEKVNINIVGDF 467
+Y GC Y+VPRA + + + G G + + + L++ + ++N VG+F
Sbjct 432 AYFGCEEGTMYFVPRAKSVVS-RIGDSIFTGCTGSWNKVTQIANMFLEQTQHSLNFVGEF 490
Query 468 KLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIG--- 524
+N+ + IL+ + + + +KG+ + + + VT G A N+G
Sbjct 491 VVNDVVLAILSGTTTNVDKIRQLLKGVTLDKLRDYLADY-DVAVTAGPFMDNAINVGGTG 549
Query 525 -EQKSILSPLYAFAS--EAARVVRSIFSRTLETAQNSV-----RVLQKAAITILD-GISQ 575
+ +I +P E+ + V +I + + ++++ VL + +D G+S
Sbjct 550 LQYAAITAPYVVLTGLGESFKKVATIPYKVCNSVKDTLTYYAHSVLYRVFPYDMDSGVSS 609
Query 576 YSLRLIDAMMFTSDLATNNLVVMAYITGGVVQ-LTSQWLTNIFGTVYEKLKPVLDWLEEK 634
+S L D + + V Y ++Q T +++ I + + +LD E
Sbjct 610 FSELLFDCVDLS--------VASTYFLVRLLQDKTGDFMSTIITSCQTAVSKLLDTCFEA 661
Query 635 FKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII 694
+ FL D + + A V ++ V+ L+NK + L +
Sbjct 662 TEATFNFLLDLAGLFRIFLRNAYVYTSQGFVVVNGKVSTLVKQVLDLLNKGMQLLHTKVS 721
Query 695 IGGAKLKA-LNLGETFVTHSKGLYRKCVKSR-----EETGLLMPLKAPKEIIFLEGETLP 748
G+ + A + G + G Y CV ++ ++ +++P + K+ + L T
Sbjct 722 WAGSNISAVIYSGRESLIFPSGTYY-CVTTKAKSVQQDLDVILPGEFSKKQLGLLQPTDN 780
Query 749 TEVLTEEVV--LKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEI--KDTEKYCALAP 804
+ ++ V + + LEQ + + +VG V I+ + + +D +
Sbjct 781 STTVSVTVSSNMVETVVGQLEQTNMHSPDV-IVGDYVIISEKLFVRSKEEDGFAFYPACT 839
Query 805 NMMVTNNTFTLKGGAP-TKVTFGDDTVIEVQGYKSVNITFELDERIDKVL-NEKCSAYTV 862
N F LKGGAP KV FG D V EV +SV + + + +D +L + + V
Sbjct 840 NGHAVPTLFRLKGGAPVKKVAFGGDQVHEVAAVRSVTVEYNIHAVLDTLLASSSLRTFVV 899
Query 863 ELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
+ + EFA VV + V L + + DLD++ A Y F+ G+ +S M
Sbjct 900 DKSLSIEEFADVVKEQVSDLLVKLLRGMPIPDFDLDDFIDAPCYCFNAEGDASWSSTMIF 959
Query 923 SFYPPDEDEEEGDCEE---EEFEPSTQYEYGTE----------DDY-----QGKPL-EFG 963
S +P + DEE + E EE E E TE D++ + PL E
Sbjct 960 SLHPVECDEECSEVEASDLEEGESECISETSTEQVDVSHEISDDEWAAAVDEAFPLDEAE 1019
Query 964 ATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQL----------- 1012
+ ++Q E + E ++D +Q + +T + VEV PQ+
Sbjct 1020 DVTESVQEEAQPVEVPVEDIAQVVIADT----LQETPVVSDTVEVPPQVVKLPSEPQTIQ 1075
Query 1013 --------------------EMELTPVVQTIEVNSFS--GYLKLTDNVYIKNADIVEEAK 1050
++ + + V+ S + +T+ V I D ++ AK
Sbjct 1076 PEVKEVAPVYEADTEQTQSVTVKPKRLRKKRNVDPLSNFEHKVITECVTIVLGDAIQVAK 1135
Query 1051 KVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL 1110
+V+VNAAN +LKHGGG+AGA+N A+ A+Q ESD+YI GPL+VG S +L GH+L
Sbjct 1136 CYGESVLVNAANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSL 1195
Query 1111 AKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVR 1170
AK+ LHVVGP+ +D+ LL Y+ N + +++ PL+SAGIFG P S + +
Sbjct 1196 AKNILHVVGPDARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAK 1255
Query 1171 TNVYLAVFDKNLYDKL 1186
T V + V +++Y L
Sbjct 1256 TRVLVVVNSQDVYKSL 1271
>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126
Score = 8038 bits (20857), Expect = 0.0, Method: Composition-based stats.
Identities = 2986/5957 (50%), Positives = 3947/5957 (66%), Gaps = 160/5957 (3%)
Query 1259 INGNLHPDSATLVSDIDITFLKKDAPYIVGD-VVQEGVLTA-----VVIPTKKAGGTTEM 1312
I G ++ S V + ++ P VGD V+ +G A VV P + +
Sbjct 1205 IAGAINKASGGDVQEESDEYISNSGPLHVGDSVLLKGYGLADAILRVVGPDARNNEDAAL 1264
Query 1313 LAKALRKV-PTDNYITTYPGQGLNG--------YTVEEAKTVLKKCKSAFYILPSIISNE 1363
L + + +T G+ Y + T + I ++ +
Sbjct 1265 LKRCYKTFNKHTIVVTPLISSGIFSVDPKVSFEYLLANVTTTTYVVVNNEDIYNTLATPS 1324
Query 1364 KQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFY 1423
K + L R + A+ +C E A V ++ K + VD G +Y
Sbjct 1325 KPDGLVYSFEGWRGTVRTAKNYGFTCFICTEYSANVKFLRTKGVDTTKKIQTVD-GVSYY 1383
Query 1424 FYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAV 1483
Y+++ + +I N + MP GYVTHGL+L ++ Y+R +KVP ++S + +
Sbjct 1384 LYSARDALTDVIAAANGC-PGICAMPFGYVTHGLDLAQSGNYVRQVKVPYVCLLASKEQI 1442
Query 1484 TAYNGYLTSSSKTPEEHFIETISLAGSYKDWSY-SGQSTQLGI---EFLKRGDKSVYYTS 1539
N + + +TPE FI ++ G Y W SG + + L +++ Y
Sbjct 1443 PIMNSDV--AIQTPETAFINNVTSNGGYHSWHLVSGDLIVKDVCYKKLLHWSGQTICYAD 1500
Query 1540 NPTTFHLDGEVITFDNLKTLLSLREVR-----TIKVFTTVDNINLHTQVVDMSMTYGQQF 1594
N + + F +L+ + R I+V T+D +N T +++ + T+ +Q
Sbjct 1501 NKFYVVKNDVALPFSDLEACRAYLTSRAAQQVNIEVLVTIDGVNFRTVILNDATTFRKQL 1560
Query 1595 GPTYLDGADVTKIKPHNSHEGKTFYVLPNDD-TLRVEAFEYYHTTDPSFLGRYMSALNHT 1653
G T+ G D++ P G++ +V N + V EYY T+D +FL RY S
Sbjct 1561 GATFYKGVDISDALPTVKMGGESLFVADNLSESEEVVLKEYYGTSDVTFLQRYYSLQPLV 1620
Query 1654 KKWKYPQVNGLTSIKWADNNCYLATALLTLQQI-ELKFNPPALQDAYYRARAGEAANFCA 1712
++WK+ +G+ S+K ++ NCY+ ++ + + ++KF PALQ+AY R + G+ +F A
Sbjct 1621 QQWKFVVHDGVKSLKLSNYNCYINATIMMIDMLHDIKFVVPALQNAYLRYKGGDPYDFLA 1680
Query 1713 LILAYCNKTVGELGDVRETMSYLFQHANLD-SCKRVLNVVCKTCGQQQTTLKGVEAVMYM 1771
LI+AY + T D + + L A L S K V C CG + G+ A +Y
Sbjct 1681 LIMAYGDCTFDNPDDEAKLLHTLLAKAELTVSAKMVWREWCTVCGIRDIEYTGMRACVYA 1740
Query 1772 GTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHG--TFTCASEYTG 1829
G S E+ + C CG + LV+ +P++++S + + + G
Sbjct 1741 GVNSMEELQSVFNETCVCGSVKHRQLVEHSTPWLLVSGLNEVKVSTSTDPVYRAFNVFQG 1800
Query 1830 -NYQCGHYKHITSKETL-YCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGV 1887
GHY H+ K+ L Y D LTK+S+ K +T V+Y + YT V Y LDGV
Sbjct 1801 VETSVGHYVHVRVKDGLFYKYDSGSLTKTSDMKCKMTSVWYPKVRYTADCNVVVYDLDGV 1860
Query 1888 VCTEIDPKLDNYYKKDNSYFTEQP-IDLVPNQPYPNASFDNFKFVCDNIKFADD-----L 1941
E++P L NYY KD Y+T +P I P P + + N V + D
Sbjct 1861 TKVEVNPDLSNYYMKDGKYYTSKPTIKYSPATILPGSVYSNSCLVGVDGTPGSDTISKFF 1920
Query 1942 NQLTGYK--KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATN 1999
N L G+ KP S++L + P+ +GDV+ ++ +Y P +KKG L KPI+W N +
Sbjct 1921 NDLLGFDETKPISKKLTYSLLPNEDGDVLLSEFNNYNPVYKKGVMLKGKPILWVNNGVCD 1980
Query 2000 KATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQK 2059
A KPN +R L+ P+ N + VL+ +Q + E PV E+V T +
Sbjct 1981 SALNKPNRASLRQLYDVAPIVLDNKYTVLQDNTSQLI-----EPNVPVVEDVS-ITTRKL 2034
Query 2060 DVLECNVKTTEVV-GDIILKPANNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVL 2117
++C V G+ N + + + +G T+L A YVD N+ + + N S +
Sbjct 2035 IEVKCKGLNKPFVKGNFSFVNDPNGVTVVDTLGLTELRALYVDINTRYIVLRDNNWSSLF 2094
Query 2118 GLKTLATHGLAAVNSVPWDT----IANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFF 2173
L T+ + L V + T + A T T ++ +
Sbjct 2095 KLHTVESGDLQIVANGGSVTRRARVLLGASSLFASFAKITVTATTAACKTAGRSFCKFVV 2154
Query 2174 TL----------------LLQLCTFTRSTNSRIKAS---MPTTIAKNTVKSVGKFCLEAS 2214
+ + S + N VK G
Sbjct 2155 NYGVLQNMFLFLKMLFFLPFNYLWPKKQPTVDVGVSGLRTAGVVTTNIVKQCGTAAYYML 2214
Query 2215 FNYLKSPNFSKLINI-------------IIWFLLLSVCLGSLIYSTAALGVLM------S 2255
K ++ + + I ++ + L S + A G+L S
Sbjct 2215 LGKFKRVDWKATLRLFLLLCTTILLLSSIYHLVIFNQVLSSDVMLEDATGILAMYKEVRS 2274
Query 2256 NLGMPSYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDSLDTYPSLETIQITISSF 2314
LG+ + C G Y N T+ + +C+ S+ C CL G DSL Y +L+ +Q I+S+
Sbjct 2275 YLGIRTLCDGLAVEYRN-TSFDVVDFCSNRSVLCQWCLIGQDSLTRYSALQMLQTHITSY 2333
Query 2315 KWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFA--VHFISNSWLMWLIINLV 2372
++ E+FLAY+L+T F VL L Q FF+Y + V++ + ++++ + LV
Sbjct 2334 VLNIDWIWFALEFFLAYVLYTSSFNVLLLVVTAQYFFAYTSAFVNWRAYNYIVSGLFFLV 2393
Query 2373 QMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRR 2432
P+ +VR+Y F A +++ K Y HV++GC + C++CYKRNR TRVE +TIV G +R
Sbjct 2394 THIPLHGLVRVYNFLACLWFLRKFYSHVINGCKDTACLLCYKRNRLTRVEASTIVCGTKR 2453
Query 2433 SFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVD 2492
+FY+ ANGG +C HNWNCV CDT G+TFI EVA DL+ +R I PTDQS Y VD
Sbjct 2454 TFYIAANGGTSYCCKHNWNCVECDTAGVGNTFICTEVANDLTTTLRRLIKPTDQSHYYVD 2513
Query 2493 SVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANN----TKGSLPINVIVFDGKSK 2548
SV VK+ + L++++ G YER+ L +F NL+ L+ G N +++D +
Sbjct 2514 SVVVKDAVVELHYNRDGSSCYERYPLCYFTNLEKLKFKEVCKTPTGIPEHNFLIYDTNDR 2573
Query 2549 CEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEK 2608
+E+ A+SA VYYSQ++C+P+LL+D LV+ VGDS E+A+KM D+++N+F S F+V +K
Sbjct 2574 GQENLARSACVYYSQVLCKPMLLVDVNLVTTVGDSREIAIKMLDSFINSFISLFSVSRDK 2633
Query 2609 LKTLVATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDVETKDVVECLKLSHQSDIEVTG 2667
L+ L+ TA + + VL TF AAR V+SDVET VV+ L+ +H++DI++T
Sbjct 2634 LEKLINTARDCVRRGDDFQTVLKTFTDAARGHAGVESDVETTMVVDALQYAHKNDIQLTT 2693
Query 2668 DSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRK 2727
+ NNY+ Y K +++ DLG ID A +N ++ N A +WN D+M LS+ ++
Sbjct 2694 ECYNNYVPGYIKPDSINTLDLGCLIDLKAASVNQTSMRNANGACVWNSGDYMKLSDSFKR 2753
Query 2728 QIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL-KGGKIVNNWL--------KQLIKVTL 2778
QIR A +K N+PF+LT + R N+++ K + K +WL K +TL
Sbjct 2754 QIRIACRKCNIPFRLTTSKLRAADNILSVKFSATKIVGGAPSWLLRVRDLTVKGYCILTL 2813
Query 2779 VFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWF 2838
VA + + P + ++ I+ YK I+ G+ RDIA D CFANK+ F WF
Sbjct 2814 FVFTVAVLSWFCLPSYSIATVNFNDDRILTYKVIENGIVRDIAPNDACFANKYGHFSKWF 2873
Query 2839 SQ-RGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICY 2897
++ GG Y N CP+ AVI G V +P T+ + F+ RVF A N+C+
Sbjct 2874 NENHGGVYRNSVDCPITIAVIAGVAGARVANVPATLAWV-GRQIVLFVSRVF-ANTNVCF 2931
Query 2898 TPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLM 2957
TP+ I Y F+ S CVL++ECT+F+DA G P+CYD VL G+ +Y ++P RY +
Sbjct 2932 TPTNEIPYDTFSDSGCVLSSECTLFRDAEGNLNPFCYDPTVLPGASSYADMKPHVRYDMY 2991
Query 2958 DGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPG 3016
D I+FP E ++R+ T ++YCR G+CE S AGVC+ST+G W L N Y + PG
Sbjct 2992 DSDMYIKFPEVIFESTLRITKTLATQYCRFGSCEESAAGVCISTNGSWALYNQNYSTRPG 3051
Query 3017 VFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSH 3076
++CG D +++ + L QP+ +S S+ G ++ + +T YY + +RA +Y+
Sbjct 3052 IYCGDDYFDIVRRLAVSLFQPVTYFQLSTSLAMGLVLCVFLTAAFYYINKVKRALADYTQ 3111
Query 3077 VVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLV 3136
+ L++ LC L Y+ +Y Y TFYLT + +F+ HI W VMF +V
Sbjct 3112 CAVVAVVAALLNSLCLCFIVANPLLVAPYTAMYYYATFYLTGEPAFIMHISWYVMFGTVV 3171
Query 3137 PFWITIAYIICISTKHFYWFFSNYLKRRV--VFNGVSFSTFEEAALCTFLLNKEMYLKLR 3194
P W+ +Y + + +H +W + + K+ V +G +F++AA F++ K+ Y+ LR
Sbjct 3172 PIWMLASYTVGVMLRHLFWVLAYFSKKHVDVFTDGKLNCSFQDAASNIFVIGKDTYVALR 3231
Query 3195 SDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQ 3254
+ + + RYL+L+NKYKY+SGAMDT SYREA HL KAL +S +GSD+LYQPP
Sbjct 3232 NAI--TQDSFVRYLSLFNKYKYYSGAMDTASYREACAAHLCKALQTYSETGSDILYQPPN 3289
Query 3255 TSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLN 3314
S+TS+VLQSG KM+ PSG VE C+VQVTCG+ TLNGLWLD+ V+CPRH++C ++ + +
Sbjct 3290 CSVTSSVLQSGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTD 3349
Query 3315 PNYEDLLIRKSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQP 3371
PNY+ LLI K+NH+F+VQ LRV+ HSM +LKL VD ANP TP Y F ++P
Sbjct 3350 PNYDALLISKTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKP 3409
Query 3372 GQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELP 3431
G +FSVLACYNG P+GV+ +R N TIKGSFL GSCGSVG+ + ++F YMH MEL
Sbjct 3410 GASFSVLACYNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVLNFVYMHQMELS 3469
Query 3432 TGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLN 3491
G H G+ +G YG F D+QT Q TD T+NV+AWLYAAV+NG +WF+ +
Sbjct 3470 NGTHTGSSFDGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIV 3529
Query 3492 DFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLE 3551
+N A+ + + L+ +TG++V M A+++ L G G+TILG + LE
Sbjct 3530 TYNEWALSNQFTEFVG--TQSIDMLAHRTGVSVEQMLAAIQSL-HAGFQGKTILGQSTLE 3586
Query 3552 DEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAF 3611
DEFTP DV Q GV QS VKR G HWL+ T++ + + ++Q T+++++ +L+E
Sbjct 3587 DEFTPDDVNMQVMGVVMQSGVKRISYGFMHWLMSTLVLAYVSVMQLTKFTMWTYLFETIP 3646
Query 3612 LPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWL 3667
+ A M VKHKH FL LFLLP + Y N+VY P +S ++ + WL
Sbjct 3647 TQMTPLLFGFMACVMFTVKHKHTFLSLFLLPVALCLTYANIVYEPQTLVSSTLIAVANWL 3706
Query 3668 DMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNAL 3727
+ L D +Y S +L ++ R + L + + Y G+
Sbjct 3707 TPTSVYMRTTHL-DFGLYISLSFVLAIIVRRLYRPSMSNLALALCSGVMWFYTYVIGDH- 3764
Query 3728 DQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLG 3787
I+ I ++TS+Y+ V + LA+ I + Y P ++ ++L+Y LG
Sbjct 3765 SSPITYLMFITTLTSDYTITVFATVNLAKFISGLVFLYAPHLGFILPEVKLVLLIYLCLG 3824
Query 3788 YFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGV 3847
Y CT YFG+F LLN R+ LGVYDY VSTQEFR++ GL P+NS +A LN KLLG+
Sbjct 3825 YMCTMYFGVFSLLNLKLRVPLGVYDYSVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGI 3884
Query 3848 GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEA 3907
GG PCIKVATVQSK++D+KCTSVVLL+VLQQL +ES+SK W+ CV+LHN+IL A D TEA
Sbjct 3885 GGTPCIKVATVQSKLTDLKCTSVVLLTVLQQLHLESNSKAWSYCVKLHNEILAAVDPTEA 3944
Query 3908 FEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQA 3967
FE+ V L + L+S VD++ L ++ +N + LQA +EFS L +YA TAQ +Y++A
Sbjct 3945 FERFVCLFATLMSFSANVDLDALANDLFENSSVLQATLTEFSHLATYAELETAQSSYQKA 4004
Query 3968 VANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVT 4026
+ +GD S VLK L+K++NVAK+ +++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+
Sbjct 4005 LNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIV 4064
Query 4027 SAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDG 4086
SAMQTMLF M++KLDND LN +I NAR+GCVPL+I+PL + KL VVIPD + + +
Sbjct 4065 SAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSIVPLCASNKLRVVIPDISVWNKVVNW 4124
Query 4087 TTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANS-AVKLQNNELS 4145
+ +YA +LW++ + + D+++V+ +++ ++ + +L WPL++ RA+S AVKLQNNE+
Sbjct 4125 PSVSYAGSLWDVTVINNVDNEVVKPTDV-VETNESLTWPLVIECSRASSSAVKLQNNEIH 4183
Query 4146 PVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTI 4205
P L+ M AG Q C+ +A+AYY +G R V+ LLS+ LKWA+ DG I
Sbjct 4184 PKGLKTMVVTAGIDQVNCS-SSAVAYYEPVQGHRMVMGLLSENAHLKWAKVEGKDGF--I 4240
Query 4206 YTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANST 4265
EL+PPC+F+ PKGP+++YLYF+K LNNL+RG +LG +AATVRLQAG TE +NST
Sbjct 4241 NIELQPPCKFLIAGPKGPEIRYLYFVKNLNNLHRGQLLGHIAATVRLQAGANTEFASNST 4300
Query 4266 VLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGAS 4325
VL+ AFAVD AKAY DY+ SGG P++N VKML TGTG AI+V PEA DQE++GGAS
Sbjct 4301 VLTLVAFAVDPAKAYLDYVGSGGTPLSNYVKMLAPKTGTGVAISVKPEATADQETYGGAS 4360
Query 4326 CCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQ 4385
CLYCR HI+HP+ G C K ++VQIP DPVGF LKN C VC W GYGC+CD
Sbjct 4361 VCLYCRAHIEHPDVSGVCKYKTRFVQIPA-HVRDPVGFLLKNVPCNVCQYWVGYGCNCDA 4419
Query 4386 LREPMLQSADAQSFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDK--VAGFAKFLK 4442
LR + + +FLNRV G S ARL PC +G +TDVVYRAFDI N K VAG K+ K
Sbjct 4420 LRNNTVPQSKDTNFLNRVRGSSVNARLEPCSSGLTTDVVYRAFDICNFKARVAGIGKYYK 4479
Query 4443 TNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDM 4502
TN CRF + D++ + +DSYF+VKRHT SNY+ E+ Y+LLKDC AVA HDFF F +D
Sbjct 4480 TNTCRFVQVDDEGHKLDSYFIVKRHTMSNYELEKRCYDLLKDCDAVAIHDFFIFDVDKTK 4539
Query 4503 VPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPD 4562
PHI RQ LT+YTM DLVYALRHFD+ NC+ LK ILV Y CC+ YF+ K W+DFVENP
Sbjct 4540 TPHIVRQSLTEYTMMDLVYALRHFDQNNCEVLKSILVKYGCCEQSYFDNKLWFDFVENPS 4599
Query 4563 ILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSG 4622
++ VY LGER+RQA+L TV+ CD M +G+VGVLTLDNQDLNG WYDFGDF+ T PG+G
Sbjct 4600 VIGVYHKLGERIRQAMLNTVKMCDHMVKSGLVGVLTLDNQDLNGKWYDFGDFVITQPGAG 4659
Query 4623 VPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYW 4682
V +VDSYYS LMP+L++T L AE+H D D KP I+W LL+YD+T+ ++ LF++YFK+W
Sbjct 4660 VAIVDSYYSYLMPVLSMTNCLAAETHKDCDFNKPLIEWLLLEYDYTDYKIGLFNKYFKHW 4719
Query 4683 DQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRE 4742
DQTYHPNCVNC DDRCILHCANFNVLFS V P TSFGP+VRKIFVDGVPF+VS GYH++E
Sbjct 4720 DQTYHPNCVNCGDDRCILHCANFNVLFSMVLPNTSFGPIVRKIFVDGVPFIVSCGYHYKE 4779
Query 4743 LGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTV 4802
LG+V N DVN+H RL+ KEL++YAADPAMH AS + L D RT CFSVAALT + FQTV
Sbjct 4780 LGLVMNMDVNIHRHRLALKELMMYAADPAMHIASASALWDLRTPCFSVAALTTGLTFQTV 4839
Query 4803 KPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLL 4862
+PGNFNKDFYDF VS+GFFKEGSSV LKHFFFAQDG+AAI+DY YY YNLPTM DI+Q+L
Sbjct 4840 RPGNFNKDFYDFVVSRGFFKEGSSVTLKHFFFAQDGHAAITDYSYYAYNLPTMVDIKQML 4899
Query 4863 FVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAY 4922
F +EVVDKYFD YDGGC+NA++VIVNNLDKSAG PFNK+GKAR+YY+SMSY++QD LFA
Sbjct 4900 FCMEVVDKYFDIYDGGCLNASEVIVNNLDKSAGHPFNKFGKARVYYESMSYQEQDELFAV 4959
Query 4923 TKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIG 4982
TKRNV+PTITQMNLKYAISAKNRARTVAGVSI STMTNRQ+HQK+LKS+AATRGAT VIG
Sbjct 4960 TKRNVLPTITQMNLKYAISAKNRARTVAGVSILSTMTNRQYHQKMLKSMAATRGATCVIG 5019
Query 4983 TSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSH 5042
T+KFYGGW MLKT+Y DVE+PHLMGWDYPKCDRAMPNM RI+ASL+LARKH+TCC+ S
Sbjct 5020 TTKFYGGWDFMLKTLYKDVESPHLMGWDYPKCDRAMPNMCRILASLILARKHSTCCTNSD 5079
Query 5043 RFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLST 5102
RFYRLANECAQVLSE V+CGG YVKPGGTSSGDATTAYANSVFNI QA TANV+AL+S
Sbjct 5080 RFYRLANECAQVLSEYVLCGGGYYVKPGGTSSGDATTAYANSVFNILQATTANVSALMSA 5139
Query 5103 DGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTY 5162
+GN I D+ ++++Q LY +YR D FV+++YA+L KHFSMMILSDD VVC+NS Y
Sbjct 5140 NGNTIIDREIKDMQFDLYINVYRKVVPDPKFVDKYYAFLNKHFSMMILSDDGVVCYNSDY 5199
Query 5163 ASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLP 5222
A++G VASI+NFK LYYQNNVFMSEAKCW ET+L KGPHEFCSQHT+ +K GDD +LP
Sbjct 5200 AAKGYVASIQNFKETLYYQNNVFMSEAKCWVETNLEKGPHEFCSQHTLYIKDGDDGYFLP 5259
Query 5223 YPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRK 5282
YPDPSRIL AGCFVDDIVKTDGT+M+ER+VSLAIDAYPLTKH + EY +VF +YLQYI K
Sbjct 5260 YPDPSRILSAGCFVDDIVKTDGTVMMERYVSLAIDAYPLTKHDDTEYQNVFWVYLQYIEK 5319
Query 5283 LHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGA 5342
L+ +LTGHMLD YSVML D+++++WE FY +Y+ T LQAVG+CV+C+SQTSLRCG
Sbjct 5320 LYKDLTGHMLDSYSVMLCGDDSAKFWEEGFYRDLYSSPTTLQAVGSCVVCHSQTSLRCGT 5379
Query 5343 CIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPP 5402
CIRRPFLCCKCCYDHVI+T+HK+VLSV+PYVCNAPGCDV+DVT+LYLGGMSYYC H+P
Sbjct 5380 CIRRPFLCCKCCYDHVIATTHKMVLSVSPYVCNAPGCDVSDVTKLYLGGMSYYCNDHRPV 5439
Query 5403 ISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETL 5462
SFPLCANG VFGLYKN C GS ++ +FN +ATCDW+++GDY LANT TE LKLFAAETL
Sbjct 5440 CSFPLCANGLVFGLYKNMCTGSSSIMEFNRLATCDWSDSGDYTLANTTTEPLKLFAAETL 5499
Query 5463 KATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEY 5522
+ATEE K SY IAT++E++ +REL L WEVGK +PPLNRNYVFTGY +TKNSKVQ+GEY
Sbjct 5500 RATEEASKQSYAIATIKEIVGERELILVWEVGKSKPPLNRNYVFTGYHLTKNSKVQLGEY 5559
Query 5523 TFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNI 5582
FE+ DY DAV Y+ +TTYKL VGD FVLTSH+V LSAPT+V QE Y++ITG+YPT+ +
Sbjct 5560 VFERIDYSDAVSYKSSTTYKLAVGDIFVLTSHSVATLSAPTIVNQERYLKITGIYPTITV 5619
Query 5583 SDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALC 5642
+EF+++V N+QK G KY T+QGPPGTGKSHFAIGLA+YYP+ARIVYTACSHAAVDALC
Sbjct 5620 PEEFANHVVNFQKAGFSKYVTVQGPPGTGKSHFAIGLAIYYPTARIVYTACSHAAVDALC 5679
Query 5643 EKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM 5702
KA KYL I KCSRIIPA+ARVEC+D+FKVN T QY+F TVNALPE + DI+V DE+SM
Sbjct 5680 AKAFKYLNIAKCSRIIPAKARVECYDRFKVNDTNAQYLFSTVNALPEISVDILVVDEVSM 5739
Query 5703 ATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFL 5762
TNYDLS++N+R++AKH VY+GDPAQLPAPRTLLT+GTLEPE FNSV RLM +GPD+FL
Sbjct 5740 CTNYDLSIINSRVKAKHIVYVGDPAQLPAPRTLLTRGTLEPENFNSVTRLMCNLGPDIFL 5799
Query 5763 GTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVRE 5822
C RCP EIV+TVSALVY+NKL A KD S QCFK+ +KG +THD SSAINRPQ+ V+
Sbjct 5800 SVCYRCPKEIVNTVSALVYNNKLSAKKDASGQCFKILFKGSVTHDASSAINRPQLNFVKT 5859
Query 5823 FLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNV 5882
F+ NP W KAVFISPYNSQNAVA +LGL TQTVDSSQGSEY YVIF QT +TAH+ N+
Sbjct 5860 FIAANPNWSKAVFISPYNSQNAVARSMLGLTTQTVDSSQGSEYPYVIFCQTADTAHANNL 5919
Query 5883 NRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITG 5942
NRFNVA+TRA+ GILC+M+ + L+D L+F L + N LQ++ VTGLFKDCS+ G
Sbjct 5920 NRFNVAVTRAQKGILCVMTSQVLFDSLEFAELSL---NNYKLQSQIVTGLFKDCSREDVG 5976
Query 5943 LHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITR 6001
L P APT+LSVD K+K T+ LCV++ I ++TY R+IS MGFK++ + GYP +FITR
Sbjct 5977 LPPAYAPTYLSVDAKYKTTDELCVNL-NITPNVTYSRVISRMGFKLDATIPGYPKLFITR 6035
Query 6002 EEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRV 6061
+EAIR VR+WIGFDVEG HA+R A GTN+PLQLGFSTGVN V P G VDT + + +
Sbjct 6036 DEAIRQVRSWIGFDVEGAHASRNACGTNVPLQLGFSTGVNFVVQPVGVVDTEWGSMLTTI 6095
Query 6062 SAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMK 6121
SA+PPPG+QFKHL+PLM KG W +VR +IVQMLSDTL LSD FV WAHGFELTS
Sbjct 6096 SARPPPGEQFKHLVPLMNKGATWPIVRRRIVQMLSDTLDKLSDYCTFVCWAHGFELTSAS 6155
Query 6122 YFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSN 6181
YF KIG E+ CC+C RRA+ FS+ +YACW HS G+DYVYNPF +DVQQWG+ GNL +N
Sbjct 6156 YFCKIGKEQRCCMCSRRASTFSSPLQSYACWSHSSGYDYVYNPFFVDVQQWGYVGNLATN 6215
Query 6182 HDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMV 6241
HD YC +H AHVAS DAIMTRCLA+++CF++RVDW + YP I E K+N+ CR V+ V
Sbjct 6216 HDRYCGIHAGAHVASSDAIMTRCLAIYDCFIERVDWDVTYPYISHEQKLNSCCRTVERNV 6275
Query 6242 VKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDK 6301
V++A+L+ KF ++DIGNPK I + + VEW FYDAQP S+K K LFY+
Sbjct 6276 VRSAVLSGKFDKIYDIGNPKGIPIISEP-VEWHFYDAQPLSNKVKK---LFYTDDVAKQ- 6330
Query 6302 FTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAF 6361
F DG+CLFWNCNV +YP+N++VCRFDTRV S NLPGC+GGSLYVNKHAFHTPA+D +AF
Sbjct 6331 FEDGLCLFWNCNVSKYPSNAVVCRFDTRVHSEFNLPGCNGGSLYVNKHAFHTPAYDINAF 6390
Query 6362 VNLKQLPFFYYSDSPCESHG-KQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYL 6420
+LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT CNLGGAVCR HA EYR Y+
Sbjct 6391 RDLKPLPFFYYSTTPCEVHGSGNMLEDIDYVPLKSAVCITACNLGGAVCRKHAAEYRDYM 6450
Query 6421 DAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIIN 6480
+AYN++ +AGF LWVYK FD YNLW+TF ++Q LEN+AFNV+ +GHF G GE+PV+++N
Sbjct 6451 EAYNIVSAAGFRLWVYKTFDIYNLWSTFVKVQGLENIAFNVIKQGHFTGVDGELPVAVVN 6510
Query 6481 NTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDY 6540
+ ++TK DV +F+N+T LP NVAFEL+AKR ++ P++ +L NL VD+ N V+WDY
Sbjct 6511 DKIFTKNGTDDVCIFKNETALPTNVAFELYAKRAVRSHPDLNLLRNLEVDVCYNFVLWDY 6570
Query 6541 KRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSV 6600
R+ +TIGVC TDI P +C FD R G ++ F + NGVLI++ +
Sbjct 6571 DRNNIYGTTTIGVCKYTDIDVNPNLNMC------FDIRDKGSLERFMSMPNGVLISDRKI 6624
Query 6601 KGLQPSVGPKQASLNGVTL--IGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPR 6658
K +GPK A NG L I F YKKV+ +T++T R + +F
Sbjct 6625 KNYPCIIGPKHAYFNGAILRNIDAKQPITFYLYKKVNNEFVSFSDTFYTCGRTVNDFTAL 6684
Query 6659 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 6718
+ ME DFL L D FI++Y LE YAFEH+VYGDFSH+ LGGLHLLIGL K+ ++ +E
Sbjct 6685 TPMEEDFLVLDSDVFIKKYSLEDYAFEHVVYGDFSHTTLGGLHLLIGLYKKMRDGHILME 6744
Query 6719 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 6778
+ + +TV NYFITD+ T S K VCSVIDL LDDFV IIK DL VVSKVVKV ID T
Sbjct 6745 EMLKDRATVHNYFITDSNTASYKAVCSVIDLRLDDFVNIIKEMDLDVVSKVVKVPIDLTM 6804
Query 6779 ISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGI 6838
I FMLWCKDG V+TFYP+LQ++ W+PG+ MP+L+K+Q+M LE C L NY S +P G+
Sbjct 6805 IEFMLWCKDGKVQTFYPRLQATNDWKPGLTMPSLFKVQQMNLEPCLLANYKQSIPMPNGV 6864
Query 6839 MMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDL 6898
MNVAKY QLCQYLNT TLAVP NMRVIHFGAG +KGVAPGT+VLRQWLP +L+D+DL
Sbjct 6865 HMNVAKYMQLCQYLNTCTLAVPANMRVIHFGAGCEKGVAPGTSVLRQWLPLDAVLIDNDL 6924
Query 6899 NDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQK 6958
N+FVSDAD T+ GDC TVH + DL+ISDMYDP TK V + N +K FF Y+C FI+
Sbjct 6925 NEFVSDADITIFGDCVTVHVGQQVDLLISDMYDPCTKAVGEVNQTKALFFVYLCNFIKNN 6984
Query 6959 LALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQID 7018
LALGGSVAIKITEHSW+ADLYK+MG FA+WT F TN NASSSE FLIG N+LG+ +E+ID
Sbjct 6985 LALGGSVAIKITEHSWSADLYKIMGRFAYWTVFCTNANASSSEGFLIGINFLGELKEEID 7044
Query 7019 GYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRL 7078
G VMHANYIFWRN+ P+ LS+YSLFD+S+FPLKL+GT V+ LKE QIN++++SLLS+G+L
Sbjct 7045 GNVMHANYIFWRNSTPMNLSTYSLFDLSRFPLKLKGTPVLQLKESQINELVISLLSQGKL 7104
Query 7079 IIRENNRVVISSDVLVN 7095
+IR+N+ + +S+DVLVN
Sbjct 7105 LIRDNDTLNVSTDVLVN 7121
Score = 1005 bits (2599), Expect = 0.0, Method: Composition-based stats.
Identities = 313/1336 (23%), Positives = 536/1336 (40%), Gaps = 189/1336 (14%)
Query 8 FNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEVLSEARQHLKD-GTCGLVEVE-KGV 60
+NEK HV ++P+ D+ L F D E ++ LK+ G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTEDMASKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETL-----GVLVPHVGEIP 115
+ L P V++ H +V +A + + TL G+ P+ +
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDHVGAAMMRTTLNVKPLGMFFPYDSSLE 139
Query 116 VAYRKVLLRKNGNKGAGGHSYGADLKS---FDLGDELGTDPYEDFQENWNTKHSSGVTRE 172
LLRKNG G D K ++ D+L DP + +N
Sbjct 140 TGEHTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCT--LSEQLDFIDTKRGVYC 230
L+++L GG VD CG +G P+ ++A+ G + + +D+ R +
Sbjct 188 LLKKLIGGDCIP-VDQYMCGKNGKPIADYAKIVAKEGLTTLADIEVDVKSRMDSDRFI-V 245
Query 231 CREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEK 290
+ + + W R Y QT F + + D P F + S I + P ++
Sbjct 246 LNKKLYRVVWNVTRRNVPYSKQTAFTVVSVIQCDD-KESVPEHTFTIGSQILMVSP-LKA 303
Query 291 KKLDGFMGRIR---SVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTE 347
F + R + Y + + + S + C+ CG +W TG+ ++ CG
Sbjct 304 TNNKNFNLKQRLLHTFYGKEAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGAN 363
Query 348 NLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGR--TI 404
+ + G +P+NA+ CP +N H+ A+ ++ K + GG+ T+
Sbjct 364 YSANDVDLQSSGLVPKNALFLANCPCANNGAC--SHNAAQVYSILDGKACVEVGGKSFTL 421
Query 405 AFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEKVN 460
FGG V++Y+GC + Y+VPRA + + + G G D ++E L+K + +
Sbjct 422 TFGGVVYAYMGCCDGTMYFVPRAKSCVS-RIGDAIFTGCTGTWDKVVETANLFLEKAQHS 480
Query 461 INIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN--FKVTKGKAKK 518
+N F L E ++LA S +TS F E +++++ + N F VT G +
Sbjct 481 LNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDYIR 537
Query 519 GAWNIGE----QKSILSPLYAFA--SEAARVVRSIFSRTLETAQNSVRVLQKAAITILDG 572
A NIG +I +P AF E+ + V +I + N L I+
Sbjct 538 DAINIGANGVCNATINAPFIAFTGLGESFKKVAAI---PWKICSNLKSALDYYCSNIMFR 594
Query 573 ISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGT----VYEKLKPVL 628
+ Y + D F L + +A + V++ + + GT L L
Sbjct 595 VFPYDIP-CDVNDFVELLLDCGKLTVA-TSYFVLRYLDEKFDTVLGTVSNACQTALSSFL 652
Query 629 DWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLAL 688
+ + F+ D +++ K + V A+ + VQ +++K + L
Sbjct 653 NACVAASRATAGFISDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLDIMSKAMKL 712
Query 689 CADSIIIGGAKLKALNL-GETFVTHSKGLYRKCVKSR-----EETGLLMPLKAPKEIIFL 742
++ G KL A+ G + + G Y C+ ++ ++ L++P K+ + +
Sbjct 713 LHTNVSWAGTKLSAIIYEGREALLFNSGTYF-CLSTKAKTLQDQMNLVLPGDYNKKTLGI 771
Query 743 -----EGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTE 797
+T+ + V + G L+P T+E + +VG V ++ + + D E
Sbjct 772 LDPVPNADTIDVTANSTVVDVVHGQLEP----TNEHGPSMIVGNYVLVSDKLFVRTDDEE 827
Query 798 KYCALAPNMMVTNNTFTLKGGAPT-KVTFGDDTVIEVQGYKSVNITFELDERIDKVL-NE 855
Y L N V + F LKGG P+ KVTFGD +EV Y+SV+IT+++ +D +L +
Sbjct 828 FYP-LCINGKVVSTLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPVLDALLSSS 886
Query 856 KCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFK 915
K + +TVE V +F V+ D V+ L P+ G D++++ Y++++ G+
Sbjct 887 KLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYVYNQDGDCA 946
Query 916 LASHMYCSFYP--------------------PDEDEEEGDCEE-EEFEPSTQYEYGTEDD 954
+S+M S P P D+EE EE P +
Sbjct 947 WSSNMTFSINPVEDVEEVEEFIEDDYLSDELPIADDEEAWTRAVEEVMPLDDILVAEIEL 1006
Query 955 YQGKPLEFGATSA-------------ALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTT 1001
+ PLE S ++ + QE DS + D
Sbjct 1007 EEDLPLETALESVEAEVGESISDELCVVETAKAQEPSVESTDSTPSTSTVVSENDLSVKP 1066
Query 1002 IQTIVEVQPQLEMEL---------------------TPVVQTIEVNSFSGYLKLTDNVYI 1040
+ + E LE+E Q V+S + ++N
Sbjct 1067 MSRVAETGDVLEVETAVVGGPVSDVTASVVTNDIVSVEQAQQCGVSSLPIQDEASENQVH 1126
Query 1041 ------------------------------------------------KNADIVEEAKKV 1052
D ++ A +
Sbjct 1127 QVPDLQCTSETKVEIVQPRQDLRPRRLRKSKVDLSKYKHTVINNSVTLVLGDAIQIASLL 1186
Query 1053 KPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAK 1112
V+VNAAN +LKHGGG+AGA+NKA+ +Q ESD+YI+ +GPL VG S +L G+ LA
Sbjct 1187 PKCVLVNAANRHLKHGGGIAGAINKASGGDVQEESDEYISNSGPLHVGDSVLLKGYGLAD 1246
Query 1113 HCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTN 1172
L VVGP+ ED LLK Y+ FN+H +++ PL+S+GIF DP S + V T
Sbjct 1247 AILRVVGPDARNNEDAALLKRCYKTFNKHTIVVTPLISSGIFSVDPKVSFEYLLANVTTT 1306
Query 1173 VYLAVFDKNLYDKLVS 1188
Y+ V ++++Y+ L +
Sbjct 1307 TYVVVNNEDIYNTLAT 1322
>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119
Score = 8033 bits (20844), Expect = 0.0, Method: Composition-based stats.
Identities = 2998/6046 (50%), Positives = 3973/6046 (66%), Gaps = 184/6046 (3%)
Query 1192 EMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIK------ACVEEVTT---- 1241
E + + + + E+ E K I + + ++ R+ K+ + T
Sbjct 1111 ENQVHQVSDLQGNELLCSETKVEIVQPRQDLKPRRSRKSKVDLSKYKHTVINNSVTLVLG 1170
Query 1242 -TLEETKFLTENLLLYI---------DINGNLHPDSATLVSDIDITFLKKDAPYIVGD-V 1290
++ L + +L+ I G ++ S V + ++ + P VGD V
Sbjct 1171 DAIQIASLLPKCILVNAANRHLKHGGGIAGVINKASGGDVQEESDEYISNNGPLHVGDSV 1230
Query 1291 VQEGVLTA-----VVIPTKKAGGTTEMLAKALRKV-PTDNYITTYPGQGLNG-------- 1336
+ +G A VV P + +L + + +T G+
Sbjct 1231 LLKGHGLADAILHVVGPDARNNEDAALLKRCYKAFNKHTIVVTPLISAGIFSVDPKVSFE 1290
Query 1337 YTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLAHAEETRKLMPVCVETK 1396
Y + T + I ++ + K + L R + A+ +C E
Sbjct 1291 YLLANVTTTTYVVVNNEDIYNTLATPSKPDGLVYSFEGWRGTVRTAKNYGFTCFICTEYS 1350
Query 1397 AIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHG 1456
A V ++ K + VD G +Y Y+++ + +I N + + MP GYVTHG
Sbjct 1351 ANVKFLRTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGCS-GICAMPFGYVTHG 1408
Query 1457 LNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGSYKDWSY 1516
L+L ++ Y+R +KVP ++S + + N + + +TPE FI ++ G Y W
Sbjct 1409 LDLAQSGNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGGYHSWHL 1466
Query 1517 -SGQSTQLGI---EFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLLSLREVR-----T 1567
SG + + L +++ Y N + + F +L+ + R
Sbjct 1467 VSGDLIVKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFSDLEACRAYLTSRAAQQVN 1526
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD-T 1626
I+V T+D +N T +++ + T+ +Q G T+ G D++ P G++ +V N +
Sbjct 1527 IEVLVTIDGVNFRTVILNDTTTFRKQLGATFYKGVDISDAFPTVKMGGESLFVADNLSES 1586
Query 1627 LRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQI 1686
+V EYY T+D +FL RY S ++WK+ +G+ S+K ++ NCY+ ++ + +
Sbjct 1587 EKVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATIMMIDML 1646
Query 1687 -ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLD-SC 1744
++KF PALQ+AY R + G+ +F ALI+AY + T D + + L A L S
Sbjct 1647 HDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKAELTVSA 1706
Query 1745 KRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
K V C CG + G+ A +Y G S E+ + C CG + LV+ +P+
Sbjct 1707 KMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLVEHSAPW 1766
Query 1805 VMMSAPPAQYELKHG--TFTCASEYTG-NYQCGHYKHITSKETL-YCIDGALLTKSSEYK 1860
+++S + + + G GHY HI K+ L Y D LTK+S+ K
Sbjct 1767 LLVSGLNEVKVSTSTDPIYRAFNVFQGVETSVGHYVHIRVKDGLFYKYDSGSLTKTSDMK 1826
Query 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQP-IDLVPNQP 1919
+T V+Y YT V Y LDGV E++P L NYY KD Y+T +P I P
Sbjct 1827 CKMTSVWYPTVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKPTIKYSPATI 1886
Query 1920 YPNASFDNFKFVCDNIKFADD-----LNQLTGYK--KPASRELKVTFFPDLNGDVVAIDY 1972
P + + N V + D N L G+ KP S++L + P+ +GDV+ ++
Sbjct 1887 LPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNEDGDVLLSEF 1946
Query 1973 KHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSED 2032
+Y P +KKG L KPI+W N + A KPN +R L+ P+ N + VL+
Sbjct 1947 SNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDNKYTVLQDNT 2006
Query 2033 AQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTE---VVGDIILKPANNSLKITEE 2089
+Q + E PV ++V P + ++E K V G+ N + + +
Sbjct 2007 SQLV-----EHNVPVVDDV---PITTRKLIEVKCKGLNKPFVKGNFSFVNDPNGVTVVDT 2058
Query 2090 VGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDT----IANYAKP 2144
+G T+L A YVD N+ + + N S + L T+ + L V + T + A
Sbjct 2059 LGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVESGDLQIVAAGGSVTRRARVLLGASS 2118
Query 2145 FLNKVVSTTTNIVTRCLNRVCTNY----------------MPYFFTLLLQLCTFTRSTNS 2188
T T + + F L +
Sbjct 2119 LFASFAKITVTATTAACKTAGRGFCKFVVNYGVLQNMFVFLKMLFFLPFNYLWPKKQPTV 2178
Query 2189 RIKAS---MPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINI-------------IIW 2232
I S + N VK G K ++ + + I
Sbjct 2179 DIGVSGLRTAGIVTTNIVKQCGTAAYYMLLGKFKRVDWKATLRLFLLLCTTILLLSSIYH 2238
Query 2233 FLLLSVCLGSLIYSTAALGVLM------SNLGMPSYCTGYREGYLNSTNVTIATYCTG-S 2285
+L + L S + A G+L S LG+ + C G Y N T+ + +C+ S
Sbjct 2239 LVLFNQVLSSDVMLEDATGILAIYKEVRSYLGIRTLCDGLVVEYRN-TSFDVMEFCSNRS 2297
Query 2286 IPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAA 2345
+ C CL G DSL Y +L+ +Q I+S+ ++ E+FLAY+L+T F VL L
Sbjct 2298 VLCQWCLIGQDSLTRYSALQMLQTHITSYVLNIDWIWFALEFFLAYVLYTSSFNVLLLVV 2357
Query 2346 IMQLFFSYFA--VHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDG 2403
Q FF+Y + V++ + ++++ + LV P+ +VR+Y F A +++ K Y HV++G
Sbjct 2358 TAQYFFAYTSAFVNWRAYNYIVSGLFFLVTHIPLHGLVRVYNFLACLWFLRKFYSHVING 2417
Query 2404 CNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGST 2463
C + C++CYKRNR TRVE +TIV G +R+FY+ ANGG +C HNWNCV CDT G+T
Sbjct 2418 CKDTACLLCYKRNRLTRVEASTIVCGTKRTFYIAANGGTSYCCKHNWNCVECDTAGVGNT 2477
Query 2464 FISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVN 2523
FI EVA DL+ +R I PTDQS Y VDSV VK+ + L++++ G YER+ L +F N
Sbjct 2478 FICTEVANDLTTTLRRLIKPTDQSHYYVDSVVVKDAVVELHYNRDGSSCYERYPLCYFTN 2537
Query 2524 LDNLRANN----TKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSD 2579
L+ L+ G N +++D + +E+ A+SA VYYSQ++C+P+LL+D LV+
Sbjct 2538 LEKLKFKEVCKTPTGIPEHNFLIYDTNDRGQENLARSACVYYSQVLCKPMLLVDVNLVTT 2597
Query 2580 VGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAAR- 2638
VGDS E+A+KM D+++N+F S F+V +KL+ L+ TA + + NVL TF AAR
Sbjct 2598 VGDSREIAIKMLDSFINSFISLFSVSRDKLEKLINTARDCVRRGDDFQNVLKTFTDAARG 2657
Query 2639 QGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARH 2698
V+SDVET VV+ L+ +H++DI++T + NNY+ Y K +++ DLG ID A
Sbjct 2658 HAGVESDVETTMVVDALQYAHKNDIQLTTECYNNYVPGYIKPDSINTLDLGCLIDLKAAS 2717
Query 2699 INAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKI 2758
+N ++ N A +WN D+M LS+ ++QIR A +K N+PF+LT + R N+++ K
Sbjct 2718 VNQTSMRNANGACVWNSGDYMKLSDSFKRQIRIACRKCNIPFRLTTSKLRAADNILSVKF 2777
Query 2759 AL-KGGKIVNNWL--------KQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGY 2809
+ K +WL K +TL VA + + P + ++ I+ Y
Sbjct 2778 SATKIVGGAPSWLLRVRDLTVKGYCILTLFVFTVAVLSWFCLPSYSIATVNFNDDRILTY 2837
Query 2810 KAIDGGVTRDIASTDTCFANKHADFDTWFSQ-RGGSYTNDKACPLIAAVITREVGFVVPG 2868
K I+ G+ RDIA D CFANK+ F WF++ GG Y N CP+ AVI G V
Sbjct 2838 KVIENGIVRDIAPNDVCFANKYGHFSKWFNENHGGVYRNSMDCPITIAVIAGVAGARVAN 2897
Query 2869 LPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGK 2928
+P + + F+ RVF A N+C+TP I Y F+ S CVL++ECT+F+DA G
Sbjct 2898 VPANLAWV-GKQIVLFVSRVF-ANTNVCFTPINEIPYDTFSDSGCVLSSECTLFRDAEGN 2955
Query 2929 PVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHG 2987
P+CYD VL G+ +Y ++P RY + D I+FP +E ++R+ T ++YCR G
Sbjct 2956 LNPFCYDPTVLPGASSYADMKPHVRYDMYDSDMYIKFPEVIVESTLRITKTLATQYCRFG 3015
Query 2988 TCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASI 3047
+CE S AGVC+ST+G W L N Y + PG++CG D +++ + L QP+ +S S+
Sbjct 3016 SCEESAAGVCISTNGSWALYNQNYSTRPGIYCGDDYFDIVRRLAISLFQPVTYFQLSTSL 3075
Query 3048 VAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSV 3107
G ++ + +T YY + +RA +Y+ + L++ LC L Y+
Sbjct 3076 AMGLVLCVFLTAAFYYINKVKRALADYTQCAVVAVVAALLNSLCLCFIVANPLLVAPYTA 3135
Query 3108 IYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV-- 3165
+Y Y TFYLT + +F+ HI W VMF +VP W+ +Y + + +H +W + + K+ V
Sbjct 3136 MYYYATFYLTGEPAFIMHISWYVMFGAVVPIWMLASYTVGVMLRHLFWVLAYFSKKHVDV 3195
Query 3166 VFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTS 3225
+G +F++AA F++ K+ Y+ LR+ + + RYL+L+NKYKY+SGAMDT S
Sbjct 3196 FTDGKLNCSFQDAASNIFVIGKDTYVALRNAI--TQDSFVRYLSLFNKYKYYSGAMDTAS 3253
Query 3226 YREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTC 3285
YREA HL KAL +S +GSD+LYQPP S+TS+VLQSG KM+ PSG VE C+VQVTC
Sbjct 3254 YREACAAHLCKALQTYSETGSDILYQPPNCSVTSSVLQSGLVKMSAPSGAVENCIVQVTC 3313
Query 3286 GTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQ---AGNVQLRVIG 3342
G+ TLNGLWLD+ V+CPRH++C ++ + +PNY+ LLI K+NH+F+VQ LRV+
Sbjct 3314 GSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLISKTNHSFIVQKHIGAQANLRVVA 3373
Query 3343 HSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGS 3402
HSM +LKL VD ANP TP Y F ++PG +FSVLACYNG P+GV+ +R N TIKGS
Sbjct 3374 HSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKGS 3433
Query 3403 FLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTT 3462
FL GSCGSVG+ + ++F YMH MEL G H G+ +G YG F D+QT Q TD
Sbjct 3434 FLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDKY 3493
Query 3463 ITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGI 3522
T+NV+AWLYAAV+NG +WF+ + +N A+ + + L+ +TG+
Sbjct 3494 CTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVG--TQSIDMLAHRTGV 3551
Query 3523 AVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHW 3582
+V M A+++ L G G+TILG + LEDEFTP DV Q GV QS VKR G HW
Sbjct 3552 SVEQMLAAIQSL-HAGFQGKTILGQSTLEDEFTPDDVNMQVMGVVMQSGVKRISYGFIHW 3610
Query 3583 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLP 3642
L+ T + + + ++Q T+++++ +L+E ++ A M VKHKH F+ LFLLP
Sbjct 3611 LISTFVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLLGFMACVMFTVKHKHTFMSLFLLP 3670
Query 3643 SLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTAR 3698
+ Y N+VY P +S ++ + WL + D +Y S +L ++ R
Sbjct 3671 VALCLTYANIVYEPQTLISSTLIAVANWLTPTSVYMRTTHF-DFGLYISLSFVLAIIVRR 3729
Query 3699 TVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGI 3758
+ L + + Y G+ I+ I ++TS+Y+ V + LA+ I
Sbjct 3730 LYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYTITVFATVNLAKFI 3788
Query 3759 VFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQ 3818
+ Y P ++ ++L+Y LGY CT YFG+F LLN R+ LGVYDY VSTQ
Sbjct 3789 SGLVFFYAPHLGFILPEVKLVLLIYLGLGYMCTMYFGVFSLLNLKLRVPLGVYDYSVSTQ 3848
Query 3819 EFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQ 3878
EFR++ GL P+NS +A LN KLLG+GG PCIKVATVQSK++D+KCTSVVLL+VLQQ
Sbjct 3849 EFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQSKLTDLKCTSVVLLTVLQQ 3908
Query 3879 LRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNR 3938
L +ES+SK W+ CV+LHN+IL A D TEAFE+ V L + L+S VD++ L ++ +N
Sbjct 3909 LHLESNSKAWSYCVKLHNEILAAVDPTEAFERFVCLFATLMSFSANVDLDALANDLFENS 3968
Query 3939 ATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAM 3997
+ LQA +EFS L +YA TAQ +Y++A+ +GD S VLK L+K++NVAK+ +++D A+
Sbjct 3969 SVLQATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAV 4028
Query 3998 QRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCV 4057
RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GCV
Sbjct 4029 ARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCV 4088
Query 4058 PLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD 4117
PL+I+PL + KL VVIPD + + + + +YA +LW+I + + D+++V+ +++ ++
Sbjct 4089 PLSIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVVKPTDV-VE 4147
Query 4118 NSPNLAWPLIVTALRANS-AVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTK 4176
+ +L WPL++ R++S AVKLQNNE+ P L+ M AG Q C + +A+AYY +
Sbjct 4148 TNESLTWPLVIECSRSSSSAVKLQNNEIHPKGLKTMVITAGVDQVNC-NSSAVAYYEPVQ 4206
Query 4177 GGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNN 4236
G R V+ LLS+ LKWA+ DG I EL+PPC+F+ PKGP+++YLYF+K LNN
Sbjct 4207 GHRMVMGLLSENAHLKWAKVEGKDGF--INIELQPPCKFLIAGPKGPEIRYLYFVKNLNN 4264
Query 4237 LNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVK 4296
L+RG +LG +AATVRLQAG TE +NSTVL+ AFAVD AKAY DY+ SGG P++N VK
Sbjct 4265 LHRGQLLGHIAATVRLQAGANTEFASNSTVLTLVAFAVDPAKAYLDYVGSGGTPLSNYVK 4324
Query 4297 MLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTC 4356
ML TGTG AI+V PEA DQE++GGAS CLYCR HI+HP+ G C K ++VQIP
Sbjct 4325 MLAPKTGTGVAISVKPEATADQETYGGASVCLYCRAHIEHPDVSGVCKYKTRFVQIPA-H 4383
Query 4357 ANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCG 4415
DPVGF LKN C VC W GYGC+CD LR + + +FLNRV G S ARL PC
Sbjct 4384 VRDPVGFLLKNVPCNVCQYWVGYGCNCDALRNNTVPQSKDTNFLNRVRGSSVNARLEPCS 4443
Query 4416 TGTSTDVVYRAFDIYNDK--VAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQ 4473
+G +TDVVYRAFDI N K VAG K+ KTN CRF + D++ + +DSYF+VKRHT SNY+
Sbjct 4444 SGLTTDVVYRAFDICNFKARVAGIGKYYKTNTCRFVQVDDEGHKLDSYFIVKRHTMSNYE 4503
Query 4474 HEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDT 4533
E+ Y+LLKDC AVA HDFF F +D PHI RQ LT+YTM DLVYALRHFD+ NC+
Sbjct 4504 LEKRCYDLLKDCDAVAIHDFFIFDVDKTKTPHIVRQSLTEYTMMDLVYALRHFDQNNCEV 4563
Query 4534 LKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGI 4593
LK ILV Y CC+ YF+ K W+DFVENP ++ VY LGER+RQA+L TV+ CD M +G+
Sbjct 4564 LKSILVKYGCCEQSYFDNKLWFDFVENPSVIGVYHKLGERIRQAMLNTVKMCDHMVKSGL 4623
Query 4594 VGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDL 4653
VGVLTLDNQDLNG WYDFGDF+ T PG+GV +VDSYYS LMP+L++T L AE+H D D
Sbjct 4624 VGVLTLDNQDLNGKWYDFGDFVITQPGAGVAIVDSYYSYLMPVLSMTNCLAAETHKDCDF 4683
Query 4654 TKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVF 4713
KP I+W LL+YD+T+ ++ LF++YFKYWDQTYHPNCVNC DDRCILHCANFNVLFS V
Sbjct 4684 NKPLIEWPLLEYDYTDYKIGLFNKYFKYWDQTYHPNCVNCSDDRCILHCANFNVLFSMVL 4743
Query 4714 PPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMH 4773
P TSFGP+VRKIFVDGVPF+VS GYH++ELG+V N D N+H RL+ KEL++YAADPAMH
Sbjct 4744 PNTSFGPIVRKIFVDGVPFIVSCGYHYKELGLVMNMDFNIHRHRLALKELMMYAADPAMH 4803
Query 4774 AASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFF 4833
AS + L D RT CFSVAALT + FQTV+PGNFNKDFYDF VS+GFFKEGSSV LKHFF
Sbjct 4804 IASASALWDLRTPCFSVAALTTGLTFQTVRPGNFNKDFYDFVVSRGFFKEGSSVTLKHFF 4863
Query 4834 FAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKS 4893
FAQDG+AAI+DY YY YNLPTM DI+Q+LF +EVVDKYFD YDGGC+NA++VIVNNLDKS
Sbjct 4864 FAQDGHAAITDYSYYAYNLPTMVDIKQMLFCMEVVDKYFDIYDGGCLNASEVIVNNLDKS 4923
Query 4894 AGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVS 4953
AG PFNK+GKAR+YY+SMSY++QD LFA TKRNV+PTITQMNLKYAISAKNRARTVAGVS
Sbjct 4924 AGHPFNKFGKARVYYESMSYQEQDELFAVTKRNVLPTITQMNLKYAISAKNRARTVAGVS 4983
Query 4954 ICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPK 5013
I STMTNRQ+HQK+LKS+AATRGAT VIGT+KFYGGW MLKT+Y DVE+PHLMGWDYPK
Sbjct 4984 ILSTMTNRQYHQKMLKSMAATRGATCVIGTTKFYGGWDFMLKTLYKDVESPHLMGWDYPK 5043
Query 5014 CDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTS 5073
CDRAMPNM RI+ASL+LARKH+TCC+ S RFYRLANECAQVLSE V+CGG YVKPGGTS
Sbjct 5044 CDRAMPNMCRILASLILARKHSTCCTNSDRFYRLANECAQVLSEYVLCGGGYYVKPGGTS 5103
Query 5074 SGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDF 5133
SGDATTAYANSVFNI QA TANV+AL+S +GN I D+ ++++Q LY +YR D F
Sbjct 5104 SGDATTAYANSVFNILQATTANVSALMSANGNTIIDREIKDMQFDLYINVYRKVVPDPKF 5163
Query 5134 VNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWT 5193
V+++YA+L KHFSMMILSDD VVC+NS YA++G VASI+NFK LYYQNNVFMSEAKCW
Sbjct 5164 VDKYYAFLNKHFSMMILSDDGVVCYNSDYAAKGYVASIQNFKETLYYQNNVFMSEAKCWV 5223
Query 5194 ETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVS 5253
ET+L KGPHEFCSQHT+ +K GDD +LPYPDPSRIL AGCFVDDIVKTDGT+M+ER+VS
Sbjct 5224 ETNLEKGPHEFCSQHTLYIKDGDDGYFLPYPDPSRILSAGCFVDDIVKTDGTVMMERYVS 5283
Query 5254 LAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFY 5313
LAIDAYPLTKH + EY +VF +YLQYI KL+ +LTGHMLD YSVML D+++++WE FY
Sbjct 5284 LAIDAYPLTKHDDTEYQNVFWVYLQYIEKLYKDLTGHMLDSYSVMLCGDDSAKFWEEGFY 5343
Query 5314 EAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYV 5373
+Y+ T LQAVG+CV+C+SQTSLRCG CIRRPFLCCKCCYDHVI+T HK+VLSV+PYV
Sbjct 5344 RDLYSSPTTLQAVGSCVVCHSQTSLRCGTCIRRPFLCCKCCYDHVIATPHKMVLSVSPYV 5403
Query 5374 CNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAI 5433
CNAPGCDV+DVT+LYLGGMSYYC H+P SFPLCANG VFGLYKN C GS ++ +FN +
Sbjct 5404 CNAPGCDVSDVTKLYLGGMSYYCNDHRPVCSFPLCANGLVFGLYKNMCTGSSSIMEFNRL 5463
Query 5434 ATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEV 5493
ATCDW+++GDY LANT TE LKLFAAETL+ATEE K SY IAT++E++ +REL L WEV
Sbjct 5464 ATCDWSDSGDYTLANTTTEPLKLFAAETLRATEEASKQSYAIATIKEIVGERELILVWEV 5523
Query 5494 GKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTS 5553
GK +PPLNRNYVFTGY +TKNSKVQ+GEY FE+ DY DAV Y+ +TTYKL VGD FVLTS
Sbjct 5524 GKSKPPLNRNYVFTGYHLTKNSKVQLGEYVFERIDYSDAVSYKSSTTYKLAVGDIFVLTS 5583
Query 5554 HTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS 5613
H+V LSAPT+V QE Y++ITG+YPT+ + +EF+++V N+QK G KY T+QGPPGTGKS
Sbjct 5584 HSVATLSAPTIVNQERYLKITGIYPTITVPEEFANHVVNFQKAGFSKYVTVQGPPGTGKS 5643
Query 5614 HFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVN 5673
HFAIGLA+YYP+ARIVYTACSHAAVDALCEKA KYL I KCSRIIPA+ARVEC+D+FKVN
Sbjct 5644 HFAIGLAIYYPTARIVYTACSHAAVDALCEKAFKYLNIAKCSRIIPAKARVECYDRFKVN 5703
Query 5674 STLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPR 5733
T QY+F TVNALPE + DI+V DE+SM TNYDLS++N+R++AKH VY+GDPAQLPAPR
Sbjct 5704 DTNSQYLFSTVNALPEISVDILVVDEVSMCTNYDLSIINSRVKAKHIVYVGDPAQLPAPR 5763
Query 5734 TLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSA 5793
TLL +GTLEPE FNSV RLM +GPD+FL C RCP EIV TVSALVY+NKL A KD S
Sbjct 5764 TLLIRGTLEPENFNSVTRLMCNLGPDIFLSVCYRCPKEIVSTVSALVYNNKLSAKKDASG 5823
Query 5794 QCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLP 5853
QCFK+ +KG +THD SSAINRPQ+ V+ F+ NP W KAVFISPYNSQNAVA +LGL
Sbjct 5824 QCFKILFKGSVTHDASSAINRPQLNFVKTFIAANPNWSKAVFISPYNSQNAVARSMLGLT 5883
Query 5854 TQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTS 5913
TQTVDSSQGSEY YVIF QT +TAH+ N+NRFNVA+TRA+ GILC+M+ + L+D L+F
Sbjct 5884 TQTVDSSQGSEYPYVIFCQTADTAHANNLNRFNVAVTRAQKGILCVMTSQVLFDSLEFAE 5943
Query 5914 LEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPK 5972
L + N LQ++ VTGLFKDCS+ TGL P APT+LSVD K+K T+ LCV++ I
Sbjct 5944 LSL---NNYKLQSQIVTGLFKDCSREDTGLPPAYAPTYLSVDAKYKTTDELCVNL-NITP 5999
Query 5973 DMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPL 6032
++TY R+IS MGFK++ + GYP +FITR+EAIR VR+W+GFDVEG HA+R A GTN+PL
Sbjct 6000 NVTYSRVISRMGFKLDATIPGYPKLFITRDEAIRQVRSWVGFDVEGAHASRNACGTNVPL 6059
Query 6033 QLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIV 6092
QLGFSTGVN V P G VDT + + +SA+PPPG+QFKHL+PLM KG W +VR +IV
Sbjct 6060 QLGFSTGVNFVVQPVGVVDTEWGSMLTTISARPPPGEQFKHLVPLMNKGATWPIVRRRIV 6119
Query 6093 QMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACW 6152
QMLSDTL LSD FV WAHGFELTS YF KIG E+ C +C RRA+ FS+ +YACW
Sbjct 6120 QMLSDTLDKLSDYCTFVCWAHGFELTSASYFCKIGKEQRCSMCSRRASTFSSPLQSYACW 6179
Query 6153 HHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFV 6212
HS G+DYVYNPF +DVQQWG+ GNL +NHD YC +H AHVAS DAIMTRCLA+++CF+
Sbjct 6180 SHSSGYDYVYNPFFVDVQQWGYVGNLATNHDRYCGIHAGAHVASSDAIMTRCLAIYDCFI 6239
Query 6213 KRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVE 6272
+RVDW + YP I E K+N+ CR V+ VV++A+L+ KF ++DIGNPK I + + VE
Sbjct 6240 ERVDWDVTYPYISHEQKLNSCCRTVERNVVRSAVLSGKFEKIYDIGNPKGIAIISEP-VE 6298
Query 6273 WKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLS 6332
W FYDAQP S+K K LFY+ F DG+CLFWNCNV +YP+N++VCRFDTRV S
Sbjct 6299 WHFYDAQPLSNKVKK---LFYTDDVSKQ-FEDGLCLFWNCNVSKYPSNAVVCRFDTRVHS 6354
Query 6333 NLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHG-KQVVSDIDYV 6391
NLPGC+GGSLYVNKHAFHTPA+D +AF +LK LPFFYYS +PCE HG ++ DIDYV
Sbjct 6355 EFNLPGCNGGSLYVNKHAFHTPAYDINAFRDLKPLPFFYYSTTPCEVHGSGNMLEDIDYV 6414
Query 6392 PLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRL 6451
PLKSA CIT CNLGGAVCR HA EYR Y++AYN++ +AGF LWVYK FD YNLW+TF ++
Sbjct 6415 PLKSAVCITACNLGGAVCRKHAAEYRDYMEAYNIVSAAGFRLWVYKTFDIYNLWSTFVKV 6474
Query 6452 QSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWA 6511
Q LEN+AFNV+ +GHF G GE+PV+++N+ ++TK DV +F+N+T LP NVAFEL+A
Sbjct 6475 QGLENIAFNVIKQGHFTGVDGELPVAVVNDKIFTKNGTDDVCIFKNETALPTNVAFELYA 6534
Query 6512 KRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPL 6571
KR ++ P++ +L NL VD+ N V+WDY R+ +TIGVC TDI P +C
Sbjct 6535 KRAVRSHPDLNLLRNLEVDVCYNFVLWDYDRNNIYGTTTIGVCKYTDIDVNPNLNMC--- 6591
Query 6572 TVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEAVKTQFN 6629
FD R G ++ F + NGVLI++ +K GPK A NG L I F
Sbjct 6592 ---FDIRDKGSLERFMSMPNGVLISDRKIKNYPCISGPKHAYFNGAILRNIDAKQPVIFY 6648
Query 6630 YYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVY 6689
YKKV+ +T++T R + +F + ME DFL L D FI++Y LE YAFEH+VY
Sbjct 6649 LYKKVNNEFVSFSDTFYTCGRTVGDFTVLTPMEEDFLVLDSDVFIKKYGLEDYAFEHVVY 6708
Query 6690 GDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDL 6749
GDFSH+ LGGLHLLIGL K+ +E +E+ + +TV NYFITD+ T S K VCSVIDL
Sbjct 6709 GDFSHTTLGGLHLLIGLYKKMREGHILMEEMLKDRATVHNYFITDSNTASYKAVCSVIDL 6768
Query 6750 LLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAM 6809
LDDFV IIK DL VVSKVVKV ID T I FMLWC+DG V+TFYP+LQ++ W+PG+ M
Sbjct 6769 RLDDFVTIIKEMDLDVVSKVVKVPIDLTMIEFMLWCRDGKVQTFYPRLQATNDWKPGLTM 6828
Query 6810 PNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFG 6869
P+L+K+Q+M LE C L NY S +P G+ MNVAKY QLCQYLNT TLAVP NMRVIHFG
Sbjct 6829 PSLFKVQQMNLEPCLLANYKQSIPMPNGVHMNVAKYMQLCQYLNTCTLAVPANMRVIHFG 6888
Query 6870 AGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDM 6929
AG +KGVAPGT+VLRQWLP +L+D+DLN+FVSDAD T+ GDC TVH + DL+ISDM
Sbjct 6889 AGCEKGVAPGTSVLRQWLPLDAVLIDNDLNEFVSDADITIFGDCVTVHVGQQVDLLISDM 6948
Query 6930 YDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWT 6989
YDP TK V + N +K FF Y+C FI+ LALGGSVAIKITEHSW+ADLYK+MG FA+WT
Sbjct 6949 YDPCTKAVGEVNQTKALFFVYLCNFIKNNLALGGSVAIKITEHSWSADLYKIMGRFAYWT 7008
Query 6990 AFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFP 7049
F TN NASSSE FLIG N+LG+ +E+IDG VMHANYIFWRN+ P+ LS+YSLFD+S+FP
Sbjct 7009 VFCTNANASSSEGFLIGINFLGELKEEIDGNVMHANYIFWRNSTPMNLSTYSLFDLSRFP 7068
Query 7050 LKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
LKL+GT V+ LKE QIN++++SLLS+G+L+IR+N+ + +S+DVLVN
Sbjct 7069 LKLKGTPVLQLKESQINELVISLLSQGKLLIRDNDTLNVSTDVLVN 7114
Score = 936 bits (2419), Expect = 0.0, Method: Composition-based stats.
Identities = 307/1330 (23%), Positives = 529/1330 (40%), Gaps = 184/1330 (14%)
Query 8 FNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEVLSEARQHLKD-GTCGLVEVE-KGV 60
+NEK HV ++P+ D+ L F D E ++ LK+ G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTDDMACKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGR-----SGETLGVLVPHVGEIP 115
+ L P V++ H +V +A + + + + LG+ P+ +
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDQVGAAMMRTTLNAKPLGMFFPYDSSLE 139
Query 116 VAYRKVLLRKNGNKGAGGHSYGADLKS---FDLGDELGTDPYEDFQENWNTKHSSGVTRE 172
LLRKNG G D K ++ D+L DP + +N
Sbjct 140 TGEYTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCT--LSEQLDFIDTKRGVYC 230
L+++L GG +D CG +G P+ ++A+ G + + +D+ R +
Sbjct 188 LLKKLIGGDCIP-IDQYMCGKNGKPIADYAKIVAKEGLTTLADIEVDVKSRMDSDRFI-V 245
Query 231 CREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEK 290
+ + + W R Y QT F I + D P F + S I + P ++
Sbjct 246 LNKKLYRVVWNVTRRNVPYPKQTAFTIVSVVQCDD-KDSVPEHTFTIGSQILMVSP-LKA 303
Query 291 KKLDGFMGRIRSVYPVAS---PNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTE 347
F + R +Y + + S + C+ CG +W TG+ ++ CG
Sbjct 304 TNNKNFNLKQRLLYTFYGKDAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGAN 363
Query 348 NLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGR--TI 404
+ + G +P+NA+ CP +N HS A+ +N K + GG+ T+
Sbjct 364 YSANDVDLQSSGLVPRNALFLANCPCANNGAC--SHSAAQVYNILDGKACVEVGGKSFTL 421
Query 405 AFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEKVN 460
FGG V++Y+GC + Y+VPRA + + + G G D ++E L+K + +
Sbjct 422 TFGGVVYAYMGCCDGTMYFVPRAKSCVS-RIGDAIFTGCTGTWDKVVETANLFLEKAQRS 480
Query 461 INIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN--FKVTKGKAKK 518
+N F L E ++LA S +TS F E +++++ + N F VT G +
Sbjct 481 LNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDYIR 537
Query 519 GAWNIGEQ----KSILSPLYAFAS--EAARVVRSIFSRTLETAQNSVRVLQKAAITILDG 572
A NIG +I +P AF E+ + V +I + N L + I+
Sbjct 538 DAINIGANGVCNATINAPFIAFTGLGESFKKVSAI---PWKICSNLKSALDYYSSNIMFR 594
Query 573 ISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGT----VYEKLKPVL 628
+ Y + D F L + +A + V++ + + GT L L
Sbjct 595 VFPYDIP-CDVSNFVELLLDCGKLTVA-TSYFVLRYLDEKFDTVLGTVSSACQTALSSFL 652
Query 629 DWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLAL 688
+ + F+ D +++ K + V A+ + VQ +++K + L
Sbjct 653 NACVAASRATAGFINDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLDIMSKAMKL 712
Query 689 CADSIIIGGAKLKALNL-GETFVTHSKGLYRKCVKSRE-----ETGLLMPLKAPKEIIFL 742
++ G KL A+ G + + G Y C+ ++ + L++P K+ + +
Sbjct 713 LHTNVSWAGTKLSAIIYEGREALLFNSGTYF-CLSTKAKTLQGQMNLVLPGDYNKKTLGI 771
Query 743 -----EGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTE 797
+T+ + V + G L+P T+E + +VG V ++ + + +D E
Sbjct 772 LDPVPNADTIDVNANSTVVDVVHGQLEP----TNEHGPSMIVGNYVLVSDKLFVRTEDEE 827
Query 798 KYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSVNITFELDERIDKVLNE- 855
Y L N V + F LKGG P+K VTFGD +EV Y+SV+IT+++ +D +L+
Sbjct 828 FYP-LCTNGKVVSTLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPVLDALLSSS 886
Query 856 KCSAYTVEL-----------------------------GTEVNEFACVVADAVIKTLQPV 886
K + +TVE G +V +F V V
Sbjct 887 KLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPC-YVYNQDGDC 945
Query 887 S-------ELLTPLGIDLDEWSMATYYLFDE----SGEFKLA------------------ 917
+ + ++ E + YL DE E A
Sbjct 946 AWSSNMTFSINPVEDVEEVEEFIEDDYLSDELPIADDEEAWARAVEEVMPLDDILVAEIE 1005
Query 918 ----SHMYCSFYPPDEDEEEGDCEEEEFEPSTQYE------YGTEDDYQGKPLEFGATSA 967
+ + + + E +E S G D T
Sbjct 1006 LEEDPPLETALESVEAEVVETAEAQEPSVESIDSTPSTSTVVGENDLSVKPMSRVAETDD 1065
Query 968 ALQPEEEQEEDWLDDDSQQTVGQ-----------------QDGSEDNQT----------- 999
L+ E + D + QD + +NQ
Sbjct 1066 VLELETAVVGGPVSDVTAIVTNDIVSVEQAQQCGVSSLPIQDEASENQVHQVSDLQGNEL 1125
Query 1000 -TTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVV 1058
+ + VQP+ +++ ++ S + + ++V + D ++ A + ++V
Sbjct 1126 LCSETKVEIVQPRQDLKPRRSRKSKVDLSKYKHTVINNSVTLVLGDAIQIASLLPKCILV 1185
Query 1059 NAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVV 1118
NAAN +LKHGGG+AG +NKA+ +Q ESD+YI+ NGPL VG S +L GH LA LHVV
Sbjct 1186 NAANRHLKHGGGIAGVINKASGGDVQEESDEYISNNGPLHVGDSVLLKGHGLADAILHVV 1245
Query 1119 GPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVF 1178
GP+ ED LLK Y+ FN+H +++ PL+SAGIF DP S + V T Y+ V
Sbjct 1246 GPDARNNEDAALLKRCYKAFNKHTIVVTPLISAGIFSVDPKVSFEYLLANVTTTTYVVVN 1305
Query 1179 DKNLYDKLVS 1188
++++Y+ L +
Sbjct 1306 NEDIYNTLAT 1315
>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124
Score = 7970 bits (20680), Expect = 0.0, Method: Composition-based stats.
Identities = 2758/5711 (48%), Positives = 3685/5711 (65%), Gaps = 216/5711 (4%)
Query 1513 DWSYSGQ-STQLGIEFLKR----GDKSVYYTSNPTTFHLDG--EVITFDNLKTLLSLREV 1565
DW + + G+ +K G+ V + +G +V + ++ LL+
Sbjct 1500 DWRLVNKFDSVDGVRTVKYFECPGEIFVSSQGKKFGYVQNGSFKVASVSQIRALLA---- 1555
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ V TVD +N + V +G+ G + DG +VTK++ H+GK F+
Sbjct 1556 NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIHKGKVFFQYSGLS 1615
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A D L +Y + L KW + K ++NNCY+ A L LQ
Sbjct 1616 AADLVAVTDAFGFDEPQLLKYYNMLGMC-KWPVVVCGNYFAFKQSNNNCYINVACLMLQH 1674
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
+ LKF+ Q+A+ R+G+ F +L+LA + E D + M + + A+L
Sbjct 1675 LSLKFHKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDSTDFMRVVLREADLSGAT 1734
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
VCK CG +Q KGV+AVM+ GTL KG I CTCG + + Q PF+
Sbjct 1735 CDFEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLAKGYTIACTCGNKLV-HCTQLNVPFL 1792
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ +TG GHY H+ K D ++K SE KG TD
Sbjct 1793 ICSNKPEGKKLPDDV-VAANIFTGG-SLGHYTHVKCKPKYQLYDACNVSKVSEAKGNFTD 1850
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPN-- 1922
Y +N T + K T+ LD V C E +P L YY + Y+T +PI + +
Sbjct 1851 CLYLKNLKQTFSSKLTTFYLDDVKCVEYNPDLSQYYCESGKYYT-KPIIKAQFRTFEKVE 1909
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I A+ N G+ E K+T +P GDVV Y +
Sbjct 1910 GVYTNFKLVGHSI--AEKFNAKLGFDCNSPFTEYKITEWPTATGDVVLASDDLYVSRYSG 1967
Query 1982 GAKLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVETSNSFD-------VLKS 2030
G KP++W H + TY +P+ C ++ PV+ S D VL +
Sbjct 1968 GCVTFGKPVIWLGHEEASLKSLTYFNRPSVVC-ENKFNVLPVDVSEPTDKGPVPAAVLVT 2026
Query 2031 EDAQGM---DNLACEDLKPVSEEVVENP-------------TIQKDVLECNVKTTEVVGD 2074
G A E S+ VV+ +++ L K +V
Sbjct 2027 GALSGAATAPGTAKEQKVCASDSVVDQVVSGFLSDLSGATVDVKEVKLNGVKKPIKVEDS 2086
Query 2075 IILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVP 2134
+++ + K+ + + D+ ++ + NELSR++ T+
Sbjct 2087 VVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWMANELSRLVNSPTV------------ 2134
Query 2135 WDTIANYAKPFLNKVVSTTTNIVTRCLNR-------------VCTNYMPYFFTLLLQLCT 2181
Y K + K+V ++ R + C + + +FF
Sbjct 2135 ----REYVKWGMTKIVIPAKLVLLRDEKQEFVAPKVVKAKVIACYSAVKWFFLYCFSWIK 2190
Query 2182 FTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLI-----NIIIWF--L 2234
F N+ K T +A ++ + + S+ ++WF L
Sbjct 2191 F----NTDNKVIYTTEVASKLTFNLCCLAFKNALQTFNWNVVSRGFFLVATVFLLWFNFL 2246
Query 2235 LLSVCLGSLI---------YSTAALGVLMSNLGMPSYCTGYRE---GYLNSTNVTIATYC 2282
+V L + + + + G+ + C Y+ GY +S +C
Sbjct 2247 YANVILSDFYLPNIGFFPTFVGQIVAWVKTTFGIFTLCDLYQVSDVGYRSS-------FC 2299
Query 2283 TGSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLTAFGLVAEWFLAYILFTRFFY 2339
GS+ C +C SG D LD Y ++ +Q + SF + ++ F LV E + Y L+T FY
Sbjct 2300 NGSMVCELCFSGFDMLDNYDAINVVQHVVDRRVSFDY-ISLFKLVVELVIGYSLYTVCFY 2358
Query 2340 VLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY 2397
L MQL ++ F+ + W + + M P ++R YI + Y ++
Sbjct 2359 PLFGLIGMQLLTTWLPEFFMLETMHWSARFFVFVANMLPAFTLLRFYIVVTAMYKIFCLC 2418
Query 2398 VHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDT 2457
HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC+NC
Sbjct 2419 RHVMYGCSRPGCLFCYKRNRSVRVKCSTVVGGTLRYYDVMANGGTGFCAKHQWNCLNCSA 2478
Query 2458 FCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHS 2517
F G+TFI+ E A DLS + KRP+NPTD + Y+V V S+ L++++ GQ+ Y+ S
Sbjct 2479 FGPGNTFITHEAAADLSKELKRPVNPTDSAYYLVTEVKQVGCSMRLFYERDGQRVYDDVS 2538
Query 2518 LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALV 2577
S FV+++ L + KG +V+V + ++ +++ +A+V+Y+Q + +P+LL+++ L+
Sbjct 2539 ASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRPMLLVEKKLI 2596
Query 2578 SDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAA 2637
+ V+ MFD YV++ +V + L + V A L + V L+ V+ TFI A
Sbjct 2597 TTANTGLSVSQTMFDLYVDSLLGVLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFIGCA 2656
Query 2638 RQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSA 2696
R+ +DSDVETK + + + + + ++ T +SCNN + TY K + + DLG I +A
Sbjct 2657 RRKCAIDSDVETKSITKSIMSAVNAGVDFTDESCNNLVPTYVKSDTIVAADLGVLIQNNA 2716
Query 2697 RHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTT 2756
+H+ A VAK+ N+A IW+V F LS L+ ++R A K L KLT V ++TT
Sbjct 2717 KHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQEANVPILTT 2776
Query 2757 KIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGV 2816
+LKGG + + L+ L V L+ V + + P + + K +K ID GV
Sbjct 2777 PFSLKGGAVFSKVLQWLFVVNLICFIV---LWALMPTYAVHKSDMQLPLYASFKVIDNGV 2833
Query 2817 TRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTIL 2874
RD+ TD CFANK FD W+ G Y N +ACP++ AVI +++G+ + +P +L
Sbjct 2834 LRDVTVTDACFANKFIQFDQWYESTFGLVYYRNSRACPVVVAVIDQDIGYTLFNVPTKVL 2893
Query 2875 RTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCY 2934
R LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P PYCY
Sbjct 2894 RY-GFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHPYCY 2952
Query 2935 DTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
++ + Y+SL P RY L + + I+FP EG VR+V T YCR G CE +E
Sbjct 2953 TEGIMHNASLYDSLAPHVRYNLANSNGYIRFPEVVSEGIVRIVRTRSMTYCRVGLCEDAE 3012
Query 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
GVC + + WVLNN YYR++PG FCG +A +L+ + L++PI ++AS VAG I+
Sbjct 3013 EGVCFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALTASSVAGAIL 3072
Query 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
AI+V YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L +Y+ Y Y T
Sbjct 3073 AIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFYTT 3132
Query 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFS 3173
Y +++S + H+QW+VM+ ++P W I Y+ + + H W FS R++ S
Sbjct 3133 LYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFS--YCRKLGTEVRSDG 3190
Query 3174 TFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCH 3233
TFEE +L TF++ KE Y KL++ V +NRYL+LYNKY+YFSG MDT +YREAAC
Sbjct 3191 TFEEMSLTTFMITKESYCKLKNSV--SDVAFNRYLSLYNKYRYFSGKMDTAAYREAACSQ 3248
Query 3234 LAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG 3292
LAKA+ F+ N+G+DVLYQPP S+T++ LQSG KM FP+ KVE C+V VT G TLNG
Sbjct 3249 LAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVFPTSKVEPCVVSVTYGNMTLNG 3308
Query 3293 LWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKL 3352
LWLDD VYCPRHVIC+S DM +P+Y +LL R + +F V +G + L V+ + MQ +L L
Sbjct 3309 LWLDDKVYCPRHVICSSADMTDPDYSNLLCRVISSDFCVMSGRMSLTVMSYQMQGSLLVL 3368
Query 3353 KVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVG 3412
V NP TPKY F ++PG+TF+VLA YNG G + MR ++TIKGSFL GSCGSVG
Sbjct 3369 TVTLQNPNTPKYSFGVVKPGETFTVLAAYNGKSQGAFHVTMRSSYTIKGSFLCGSCGSVG 3428
Query 3413 FNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLY 3472
+ + D V F YMH +EL TG H GTD GNFYGP+ D Q Q D T TVNV+AWLY
Sbjct 3429 YVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAWLY 3488
Query 3473 AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLK 3532
AA++N WF+ + +L +FN+ AM + + D V L L++ TG+ V + A++K
Sbjct 3489 AAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQILAAIK 3546
Query 3533 ELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLL 3592
L +G G+ ILGS +LEDE TP DV +Q +GV QS R +KGT W+L + L
Sbjct 3547 RLY-SGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVVKGTCCWILASTLLFCS 3605
Query 3593 VLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN- 3651
++ +W++F ++ + L + + +FAM+ VKHKH +L +F++P L T+ Y N
Sbjct 3606 IISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLVKHKHLYLTMFIMPVLCTLFYTNY 3664
Query 3652 MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTL 3711
+V S+ WL ++ + + + +V ++ +T R++ D ++ +
Sbjct 3665 LVVYKQSFRGLAYAWLSHFVPAVDYTYMDEVLYGVVLLVAMVFVTMRSINHDVFSVMFLV 3724
Query 3712 MNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFI 3771
+++LV Y+G L++ + ++ + S+ Y+ + A+ ++ + ++F
Sbjct 3725 GRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTWTTMLSLATAK-VIAKWLAVNVLYFT 3781
Query 3772 TGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPP 3831
++ ++L Y +GY C CY+G+ LLN FR+ LGVY+Y +S QE RYMN+ GL PP
Sbjct 3782 DVPQVKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISVQELRYMNANGLRPP 3841
Query 3832 KNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQC 3891
+NS +A LN KLLG+GG P I+V+ +QS+++DVKC +VVLL+ LQ L + SSSKLW C
Sbjct 3842 RNSFEALVLNFKLLGIGGVPVIEVSQIQSRLTDVKCVNVVLLNCLQHLHIASSSKLWQYC 3901
Query 3892 VQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQAIA 3945
LHN+IL D + AF+K+ LL VL + AVD I ++ ++ + + LQA+
Sbjct 3902 STLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDSTVLQALQ 3961
Query 3946 SEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKM 4004
SEF ++ S+ + A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ RKLE+M
Sbjct 3962 SEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKLERM 4021
Query 4005 ADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPL 4064
AD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 4022 ADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKLDNQALNSILDNAVKGCVPLNAIPS 4081
Query 4065 TTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAW 4124
T+ L +++PD + D TYA +W IQ + DAD + QL+EI + N+ W
Sbjct 4082 LTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQLNEIDV----NITW 4137
Query 4125 PLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVL 4182
PL++ A R N S+V LQNNEL P LR +G+ T YYNTT G+ V
Sbjct 4138 PLVIAANRHNEVSSVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQ--CYYNTTGMGKIVY 4195
Query 4183 ALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMV 4242
A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V
Sbjct 4196 AILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNTLARGWV 4254
Query 4243 LGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHT 4302
+G+L++TVRLQAG ATE +NS + S CAF+VD K Y DY+ GG P+TNCVKMLC H
Sbjct 4255 VGTLSSTVRLQAGTATEYASNSAIRSLCAFSVDPKKTYLDYIQQGGAPVTNCVKMLCDHA 4314
Query 4303 GTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVG 4362
GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV
Sbjct 4315 GTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-IKDPVS 4373
Query 4363 FTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTGTSTD 4421
+ L + VC VCG W+ CSC QS D +FLNRV G S ARL PC +G TD
Sbjct 4374 YVLTHDVCQVCGFWRDGSCSCVGT-GSQFQSKDT-NFLNRVRGTSVNARLVPCASGLDTD 4431
Query 4422 VVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNL 4481
V RAFDI N AG + K NCCRFQ DED N +D +FV+KR Y E+ Y L
Sbjct 4432 VQLRAFDICNANRAGIGLYYKVNCCRFQRADEDGNTLDKFFVIKRTNLEVYNKEKECYEL 4491
Query 4482 LKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTY 4541
K+C VA+H+FF F ++G VPHI R+ L+KYTM DL YALRHFD +C TLKEIL+TY
Sbjct 4492 TKECGVVAEHEFFTFDVEGSRVPHIVRKDLSKYTMLDLCYALRHFDRNDCSTLKEILLTY 4551
Query 4542 NCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDN 4601
CD+ YF KKDWYDFVEN DI+ VY LG +ALL T +F D + AG+VGVLTLDN
Sbjct 4552 AECDESYFQKKDWYDFVENSDIINVYKKLGPIFNRALLNTAKFADTLVEAGLVGVLTLDN 4611
Query 4602 QDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWD 4661
QDL G WYDFGDF++T PG GV V DSYYS +MP+LT+ AL +E ++ Y ++D
Sbjct 4612 QDLYGQWYDFGDFVKTVPGCGVAVADSYYSYMMPMLTMCHALDSELFIN----GTYREFD 4667
Query 4662 LLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPL 4721
L++YDFT+ +L+LF++YFKYW TYHPN C DDRCI+HCANFN+LFS V P T FGPL
Sbjct 4668 LVQYDFTDFKLELFNKYFKYWSMTYHPNTCECEDDRCIIHCANFNILFSMVLPKTCFGPL 4727
Query 4722 VRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLL 4781
VR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+LL+YAADPA+H AS + LL
Sbjct 4728 VRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYRLSLKDLLLYAADPALHVASASALL 4787
Query 4782 DKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAA 4841
D RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +SKG KEGSSV+LKHFFF QDGNAA
Sbjct 4788 DLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSVDLKHFFFTQDGNAA 4847
Query 4842 ISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKW 4901
I+DY+YY+YNLPTM DI+QLLFV+EVV+KYF+ YDGGCI A QVIVNN DKSAG+PFNK+
Sbjct 4848 ITDYNYYKYNLPTMVDIKQLLFVLEVVNKYFEIYDGGCIPATQVIVNNYDKSAGYPFNKF 4907
Query 4902 GKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNR 4961
GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI STMT R
Sbjct 4908 GKARLYYEALSFEEQDEVYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILSTMTGR 4967
Query 4962 QFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNM 5021
FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPKCDRAMPN+
Sbjct 4968 MFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPKCDRAMPNI 5027
Query 5022 LRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAY 5081
LRI++SLVLARKH +CCS + RFYRLANECAQVLSE+VMCGG YVKPGGTSSGDATTA+
Sbjct 5028 LRIISSLVLARKHDSCCSHTDRFYRLANECAQVLSEIVMCGGCYYVKPGGTSSGDATTAF 5087
Query 5082 ANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYL 5141
ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD FVNE+Y +L
Sbjct 5088 ANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVNEYYEFL 5147
Query 5142 RKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGP 5201
KHFSMMILSDD VVC+NS +AS+G +A+I F+ VLYYQNNVFMSEAKCW ETD+ KGP
Sbjct 5148 NKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQVLYYQNNVFMSEAKCWVETDIEKGP 5207
Query 5202 HEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPL 5261
HEFCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFVSLAIDAYPL
Sbjct 5208 HEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFVSLAIDAYPL 5267
Query 5262 TKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHT 5321
H N EY +VF +YL+YI+KL+++L +LD YSV+L+ + ++ + FY+ MY
Sbjct 5268 VYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSYSVILSTCDGQKFTDETFYKNMYLRSA 5327
Query 5322 VLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDV 5381
V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC YDHV+ST HK VLSV+PYVCN+PGCDV
Sbjct 5328 VMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVLSVSPYVCNSPGCDV 5387
Query 5382 TDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNA 5441
DVT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS + DFN IA+C WT
Sbjct 5388 NDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYIEDFNKIASCKWTEV 5447
Query 5442 GDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLN 5501
DY+LAN CTERLKLFAAET KATEE+FK Y AT+RE++SDREL LSWE+GK RPPLN
Sbjct 5448 DDYVLANECTERLKLFAAETQKATEESFKQCYASATIREIVSDRELILSWEIGKVRPPLN 5507
Query 5502 RNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSA 5561
+NYVFTGY T N K +GEY F+K + + V YR TTTYKL+VGD F+LTSH V LSA
Sbjct 5508 KNYVFTGYHFTSNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFILTSHAVSSLSA 5567
Query 5562 PTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGL 5619
PTLVPQE+Y +R +Y ++ + F +NV NYQ +GM++Y T+QGPPGTGKSH AIGL
Sbjct 5568 PTLVPQENYTSIRFASVY---SVPETFQNNVPNYQHIGMKRYCTVQGPPGTGKSHLAIGL 5624
Query 5620 ALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQY 5679
A+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RV+C+DKFKVN T +Y
Sbjct 5625 AVYYCTARVVYTAASHAAVDALCEKAYKFLNINDCTRIVPAKVRVDCYDKFKVNDTTRKY 5684
Query 5680 VFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKG 5739
VF T+NALPE DI+V DE+SM TNY+LSV+N+R+RAKHYVYIGDPAQLPAPR LL KG
Sbjct 5685 VFTTINALPELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGDPAQLPAPRVLLNKG 5744
Query 5740 TLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMF 5799
TLEP YFNSV +LM +GPD+FLGTC RCP EIVDTVSALVY NKLKA D S+ CFK++
Sbjct 5745 TLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYHNKLKAKNDNSSMCFKVY 5804
Query 5800 YKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDS 5859
YKG TH+ SSA+N QI ++ +FL NP+W AVFISPYNSQN VA ++LGL TQTVDS
Sbjct 5805 YKGQTTHESSSAVNMQQIYLISKFLKANPSWSNAVFISPYNSQNYVAKRVLGLQTQTVDS 5864
Query 5860 SQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRR 5919
+QGSEYD+VI++QT ETAHS NVNRFNVAITRAK GILC+MS L++ L F++L + +
Sbjct 5865 AQGSEYDFVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSSMQLFESLNFSTLTLDKI 5924
Query 5920 NVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDMTYRR 5978
N LQ T LFKDCS+ G HP AP+ L+VD K+K G L V + +TY R
Sbjct 5925 NNPRLQ--CTTNLFKDCSRSYAGYHPAHAPSFLAVDDKYKVGGDLAVCLNVADSAVTYSR 5982
Query 5979 LISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFST 6038
LIS+MGFK++ ++GY +FITR+EAIR VRAW+GFD EG HATR+++GTN PLQLGFST
Sbjct 5983 LISLMGFKLDLTLDGYCKLFITRDEAIRRVRAWVGFDAEGAHATRDSIGTNFPLQLGFST 6042
Query 6039 GVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDT 6098
G++ V TG + F + A+ PPG+QFKHL+PLM +G W+VVRI+IVQMLSD
Sbjct 6043 GIDFVVEATGMFAERDGYVFKKAVARAPPGEQFKHLVPLMSRGQKWDVVRIRIVQMLSDH 6102
Query 6099 LKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGF 6158
L +L+D VV V WA FELT ++YF K+G E C +C++RATCF++ + Y CW HS
Sbjct 6103 LVDLADSVVLVTWAASFELTCLRYFAKVGKEVVCSVCNKRATCFNSRTGYYGCWRHSYSC 6162
Query 6159 DYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWT 6218
DY+YNP ++D+QQWG+TG+L SNHDL C VH AHVAS DAIMTRCLAVH+CF K V+W+
Sbjct 6163 DYLYNPLIVDIQQWGYTGSLTSNHDLICSVHKGAHVASSDAIMTRCLAVHDCFCKSVNWS 6222
Query 6219 IEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDA 6278
+EYPII +E+ +N +CR +Q ++ +AA+L +++ V +DIGNPK + CV D +KFYDA
Sbjct 6223 LEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKGYD--FKFYDA 6280
Query 6279 QPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPG 6338
P +++ Y Y H D+F DG+C+FWNCNVD+YPAN++VCRFDTRVL+ LNLPG
Sbjct 6281 SPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLNKLNLPG 6337
Query 6339 CDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATC 6398
C+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD+PC +DYVPL+SATC
Sbjct 6338 CNGGSLYVNKHAFHTSPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLRSATC 6397
Query 6399 ITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVA 6458
ITRCNLGGAVC HA +YR YL++YN +AGF+ WVYK FD YNLWNTFTRLQSLENV
Sbjct 6398 ITRCNLGGAVCLKHAEDYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQSLENVV 6457
Query 6459 FNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPV 6518
+N+VN GHFDG+ GE+P ++I V K+ DV +F+N T P NVA EL+AKR+I+P
Sbjct 6458 YNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAKRSIRPH 6517
Query 6519 PEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGR 6578
PE+K+ NL +D+ + V+WDY +D+ ST VC TD+ L V FDGR
Sbjct 6518 PELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVCKYTDL------QCIESLNVLFDGR 6571
Query 6579 VDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI---GEAVKTQFNYYKKVD 6635
+G ++ F+ R+GV I +K L GP++A LNGV + V+ F + D
Sbjct 6572 DNGALEAFKKCRDGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFAMRRDGD 6631
Query 6636 GVVQQLP-------------------------------ETYFTQSRNLQEFKPRSQMEID 6664
V+ T FTQSR L F PRS+ME D
Sbjct 6632 DVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRFLSSFAPRSEMEKD 6691
Query 6665 FLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMD 6724
F++L D FI +Y L+ YAFEH+VYG F+ +GGLHLLIGLA+R ++S +++F+P D
Sbjct 6692 FMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRQQKSNLVIQEFVPYD 6751
Query 6725 STVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLW 6784
S++ +YFITD +GSSK VC+VIDLLLDDFV+I+KS +L+ VSKVV V +D+ + FMLW
Sbjct 6752 SSIHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKSLNLNCVSKVVNVNVDFKDFQFMLW 6811
Query 6785 CKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAK 6844
C + V TFYP+LQ++ W+PG MP LYK LE+ +L NYG TLP G +MNVAK
Sbjct 6812 CNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPLERVNLWNYGKPITLPTGCLMNVAK 6871
Query 6845 YTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSD 6904
YTQLCQYLNT TLAVP NMRV+H GAGSDK VAPG+AVLRQWLP G++LVD+D+N FVSD
Sbjct 6872 YTQLCQYLNTTTLAVPANMRVLHLGAGSDKDVAPGSAVLRQWLPAGSILVDNDINPFVSD 6931
Query 6905 ADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGS 6964
+ ++ G+C T+ A +WDLIISDMYDP TKN+ + N SK+GFFTY+C I+ KLALGGS
Sbjct 6932 SVASYYGNCITLPIACQWDLIISDMYDPLTKNIGEYNVSKDGFFTYLCHLIRDKLALGGS 6991
Query 6965 VAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHA 7024
VAIKITE SWNA+LY LMG FA+WT F TNVNASSSE FLIG N+L + R +IDG MHA
Sbjct 6992 VAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWLNRTRTEIDGKTMHA 7051
Query 7025 NYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENN 7084
NY+FWRN+ +YSLFDMSKFPLK+ GTAV+SLK QIND++LSL+ KG+L++R+
Sbjct 7052 NYLFWRNSTMWNGGAYSLFDMSKFPLKVAGTAVVSLKPDQINDLVLSLIEKGKLLVRDTR 7111
Query 7085 RVVISSDVLVN 7095
+ V D LVN
Sbjct 7112 KEVFVGDSLVN 7122
Score = 600 bits (1548), Expect = 7e-170, Method: Composition-based stats.
Identities = 227/1099 (21%), Positives = 390/1099 (35%), Gaps = 194/1099 (18%)
Query 2 ESLVPGFNEKTHVQLS---LPVLQ-------VRDVLVRGFGDSVEEVLSEARQHLKDGTC 51
E G HV++ LP L+ +RD+ V + V + L+ G+
Sbjct 46 EPKTKGKTLINHVRVDCSRLPALECCVQSAIIRDIFV---DEDPLNVEASTMMALQFGSA 102
Query 52 GLVEVEK----------GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQY 97
LV+ K GVLP+ +F + T HV +L + +G+
Sbjct 103 VLVKPSKRLSIQAWAKLGVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCL 162
Query 98 GRSGETLGVLVPHVGEIPVAYRK------VLLRKNGNKGA---GGHSYGADLKSFDLGDE 148
G +G +G VP V IP ++ +LLRK GNKG+ G + +D E
Sbjct 163 G-NGRFIGWFVP-VTAIPAYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE 220
Query 149 LGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARA 208
D E+ N K+S L++ G ++D C G + L
Sbjct 221 ---DACEEVHLNPKGKYSRK-AYALLKGYRGVKSILFLDQYGCDYTGR----LAKGLEDY 272
Query 209 GKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKS-YELQTPFEIKLAKKF---- 263
G CTL E + ++E +AW+ +R ++ LQT I+
Sbjct 273 G--DCTLEEMKELFPVWCDSL---DNEVVVAWHVDRDPRAVMRLQTLATIRSIGYVGQPT 327
Query 264 -DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLS 318
D +G+ P + N+I+K + PR+ + L Y +C +
Sbjct 328 EDLVDGDVVVREPAHLLAANAIVKRL-PRLVETMLYTDSSVTEFCYKTK-LCDCGFITQF 385
Query 319 TLMKC--DHCGETSWQTGDFVKATCE-FCGTENLTKE-GATTCGYLPQNAVVKIYCPACH 374
+ C D C W G+ + C + E A + G +P+ V+
Sbjct 386 GYVDCCGDACDFRGWVPGNMMDGFLCPGCSKSYMPWELEAQSSGVIPKGGVL-------- 437
Query 375 NSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVF--SYVGCHNKCAYWVPRASANIG 432
+ + ++ G + FG V+ Y G W+P +++
Sbjct 438 ---------FTQSTDTVNRESFKLYGHAVVPFGSAVYWSPYPG------MWLPVIWSSVK 482
Query 433 C----NHTGVVGEGS-EGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAF 487
+TGVVG + D + L + V + G+ E+ AI+
Sbjct 483 SYADLTYTGVVGCKAIVQETDAICRSLYMDYVQ-HKCGNL---EQRAIL----------- 527
Query 488 VETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSI 547
GLD +Q++ + G++ + +L + F R+
Sbjct 528 -----GLDDVYHRQLLVNRGDYSL-----------------LLENVDLFVKR-----RAE 560
Query 548 FSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA-MMFTSDLA------TNNLVVMAY 600
F+ T + + L +LDG+ S LI + FTS + T+ + MA
Sbjct 561 FACKFATCGDGLVPL------LLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMAL 614
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRD------GWEIVKFIST 654
+ V++ ++++ + G + + K + + K E + D GW + ++
Sbjct 615 LFMHDVKVATKYVKKVTGKLAVRFKALGVAVVRKITEWFDLAVDTAASAAGWLCYQLVN- 673
Query 655 CACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII---IGGAKLKALNLGETFVT 711
V +T ++ E V+ F F + DS+ + G + +
Sbjct 674 -GLFAVANGGITFLSDVPELVKNFVDKFKVFFKVLIDSMSVSVLSGLTVVKTASNRVCLA 732
Query 712 HSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS 771
K +Y + + +MP+ E L GE P V + V + L
Sbjct 733 GCK-VYEVVQ--KRLSAYVMPVGCN-EATCLVGEIEPAVVEDDVVDVVKAPLT-----YQ 783
Query 772 EAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPN-MMVTNNTFTLKGGAPTKVTFGDDT- 829
+ P +C+ + + + Y + N + + A KV F D
Sbjct 784 GCCKPPTSFEKICVVDKLYMAKCGDQFYPVVVDNDTIGVLDQCWRFPCAGKKVEFNDKPK 843
Query 830 VIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE- 888
V E+ + + I F LD D VL++ CS + V+ ++E VV DAV TL P E
Sbjct 844 VKEIPSTRKIKINFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEH 903
Query 889 --LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ 946
+ T + L+ + YLFDE GE +A MYCSF PD++ DC + + +
Sbjct 904 DVIGTKVCALLNRLAEDYVYLFDEGGEEVIAPKMYCSFSAPDDE----DCVAADVVDADE 959
Query 947 YEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIV 1006
+ DD +A + QEED + Q V + D D V
Sbjct 960 NQGDDADD------------SAALVTDTQEEDGV-AKGQVGVAESDARLDQVEAFDIEKV 1006
Query 1007 EVQPQLEMELTPVVQTIEV 1025
E E+ +
Sbjct 1007 EDPILNELSAELNAPADKT 1025
Score = 186 bits (473), Expect = 6e-45, Method: Composition-based stats.
Identities = 66/252 (26%), Positives = 115/252 (46%), Gaps = 18/252 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV D+++ ++V V+VN AN + HG GVAGA+ KA + E+ D +
Sbjct 1266 CITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKSFIKETADMVK 1325
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHEVLLAPLLS 1150
G +VG +G NL K L++VGP+ + L+ AY++ N+ + ++ L+S
Sbjct 1326 NQGVCQVGECYESTGGNLCKTVLNIVGPDARGHGKQCYSFLERAYQHINKCDDVVTTLIS 1385
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + V NV L +K+ +D + + K + ++A+
Sbjct 1386 AGIFSVPTDVSLTYLIGVVTKNVILVSNNKDDFDVIEKCQVTSIAGTKALSLQLAKNLCR 1445
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+VK F T + S+ +C L+E + L ++ L ++ + +
Sbjct 1446 DVK-FETNACDSLFSD--------SCFVSSYDVLQEVELLRHDIQLDDDARVFVQAHMDN 1496
Query 1264 HPDSATLVSDID 1275
P LV+ D
Sbjct 1497 LPADWRLVNKFD 1508
Score = 45.8 bits (107), Expect = 0.025, Method: Composition-based stats.
Identities = 45/239 (19%), Positives = 82/239 (34%), Gaps = 28/239 (12%)
Query 1574 VDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDT-LRVEAF 1632
D + V S Q + D+ K++ +E P D T V AF
Sbjct 978 EDGVAKGQVGVAESDARLDQV-----EAFDIEKVEDPILNELSAELNAPADKTYEDVLAF 1032
Query 1633 EYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNP 1692
+ + L + + +K G S NC+L + L+ +Q + L+F
Sbjct 1033 DAIY---SEALSAFYAVPGDETHFKVC---GFYSPAIERTNCWLRSTLIVMQSLPLEFKD 1086
Query 1693 PALQDAYYRARAGEAANFCALILAYCNKTVGEL--GDVRETMSYLFQHANLDSCKRVLNV 1750
+Q + ++ F ++ K++ G V + + S K N
Sbjct 1087 LEMQKLWLSYKSSYNKEFVDKLVKSVPKSIILPQGGYVADFAYFFLSQ---CSFKAYANW 1143
Query 1751 VCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSA 1809
C C L+G++A+ + G + V C CG T L+ + P+ +
Sbjct 1144 RCLKCDM-DLKLQGLDAMFFYGDV--------VSHVCKCGTGMT--LLSADIPYTLHFG 1191
>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176
Score = 7960 bits (20655), Expect = 0.0, Method: Composition-based stats.
Identities = 2762/5714 (48%), Positives = 3680/5714 (64%), Gaps = 223/5714 (4%)
Query 1513 DWSYSGQ-STQLGIEFLKR----GDKSVYYTSNPTTFHLDG--EVITFDNLKTLLSLREV 1565
DW + + G+ +K G V + +G + + ++ LL+
Sbjct 1553 DWRLVNKFDSVDGVRTIKYFECPGGIFVSSQGKKFGYVQNGSFKEASVSQIRALLA---- 1608
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ V TVD +N + V +G+ G + DG +VTK++ ++GK F+ +
Sbjct 1609 NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIYKGKVFFQYSDLS 1668
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A + D L +Y + L KW + K ++NNCY+ A L LQ
Sbjct 1669 EADLVAVKDAFGFDEPQLLKYYTMLGMC-KWPVVVCGNYFAFKQSNNNCYINVACLMLQH 1727
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
+ LKF Q+A+ R+G+ F +L+LA + E D + M + + A+L
Sbjct 1728 LSLKFPKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDSIDFMRVVLREADLSGAT 1787
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
L VCK CG +Q KGV+AVM+ GTL +G I CTCG + + Q PF+
Sbjct 1788 CNLEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLVRGYNIACTCGSKLV-HCTQFNVPFL 1845
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ +TG GHY H+ K D + K SE KG TD
Sbjct 1846 ICSNTPEGRKLPDDV-VAANIFTGG-SVGHYTHVKCKPKYQLYDACNVNKVSEAKGNFTD 1903
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--N 1922
Y +N T + T+ LD V C E P L YY + Y+T +PI + + +
Sbjct 1904 CLYLKNLKQTFSSVLTTFYLDDVKCVEYKPDLSQYYCESGKYYT-KPIIKAQFRTFEKVD 1962
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I A+ LN G+ E K+T +P GDVV Y +
Sbjct 1963 GVYTNFKLVGHSI--AEKLNAKLGFDCNSPFVEYKITEWPTATGDVVLASDDLYVSRYSS 2020
Query 1982 GAKLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVETSNSFD-------VLKS 2030
G KP+VW H + TY +P+ C ++ PV+ S D VL +
Sbjct 2021 GCITFGKPVVWLGHEEASLKSLTYFNRPSVVC-ENKFNVLPVDVSEPTDKGPVPAAVLVT 2079
Query 2031 E----DAQGMDNLACEDLKPVSEEVVENP-------------TIQKDVLECNVKTTEVVG 2073
DA +A E S V + +++ L K +V G
Sbjct 2080 GVPGADASAGAGIAKEQKACASASVEDQVVTEVRQEPSVSAADVKEVKLNGVKKPVKVEG 2139
Query 2074 DIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSV 2133
+++ + K+ + + D+ ++ + NELSR++ T+
Sbjct 2140 SVVVNDPTSETKVVKSLSIVDVYDMFLTGCKYVVWTANELSRLVNSPTV----------- 2188
Query 2134 PWDTIANYAKPFLNKVVSTTTNIVTRCLNR-------------VCTNYMPYFFTLLLQLC 2180
Y K + K+V+ ++ R + C + +F
Sbjct 2189 -----REYVKWGMGKIVTPAKLLLLRDEKQEFVAPKVVKAKAIACYCAVKWFLLYCFSWI 2243
Query 2181 TFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLIN--------IIIW 2232
F N+ K T +A K K C A N L++ N+S + ++W
Sbjct 2244 KF----NTDNKVIYTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVFLLW 2296
Query 2233 F--LLLSVCLGSLI---------YSTAALGVLMSNLGMPSYCTGYRE---GYLNSTNVTI 2278
F L +V L + + + G+ + C Y+ GY +S
Sbjct 2297 FNFLYANVILSDFYLPNIGPLPTFVGQIVAWFKTTFGVSTICDFYQVTDLGYRSS----- 2351
Query 2279 ATYCTGSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLTAFGLVAEWFLAYILFT 2335
+C GS+ C +C SG D LD Y ++ +Q + SF + ++ F LV E + Y L+T
Sbjct 2352 --FCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRLSFDY-ISLFKLVVELVIGYSLYT 2408
Query 2336 RFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYV 2393
FY L + MQL ++ F+ + W L + + M P ++R YI + Y V
Sbjct 2409 VCFYPLFVLIGMQLLTTWLPEFFMLETMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKV 2468
Query 2394 WKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCV 2453
+ HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC+
Sbjct 2469 YCLCRHVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCL 2528
Query 2454 NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTY 2513
NC+++ G+TFI+ E A DLS + KRP+NPTD + Y V V S+ L++++ GQ+ Y
Sbjct 2529 NCNSWKPGNTFITHEAAADLSKELKRPVNPTDSAYYSVTEVKQVGCSMRLFYERDGQRVY 2588
Query 2514 ERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLD 2573
+ + S FV+++ L + KG +V+V + ++ +++ A+V+Y+Q + +P+L+++
Sbjct 2589 DDVNASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLGAAVFYAQSLYRPMLMVE 2646
Query 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
+ L++ V+ MFD YV++ + +V + L + V A L + V L+ V+ TF
Sbjct 2647 KKLITTANTGLSVSRTMFDLYVDSLLNVLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTF 2706
Query 2634 ISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACI 2692
I AR+ +DSDVETK + + + + + ++ T +SCNN + TY K + + DLG I
Sbjct 2707 IGCARRKCAIDSDVETKSITKSVMSAVNAGVDFTDESCNNLVPTYVKSDTIVAADLGVLI 2766
Query 2693 DCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVN 2752
+A+H+ A VAK+ N+A IW+V F LS L+ ++R A K L KLT V
Sbjct 2767 QNNAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQEANVP 2826
Query 2753 VVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAI 2812
++TT +LKGG + + L+ L L+ V + + P + + K +K I
Sbjct 2827 ILTTPFSLKGGAVFSRMLQWLFVANLICFIV---LWALMPTYAVHKSDMQLPLYASFKVI 2883
Query 2813 DGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLP 2870
D GV RD++ TD CFANK FD W+ G Y N KACP++ AVI +++G + +P
Sbjct 2884 DNGVLRDVSVTDACFANKFNQFDQWYESTFGLAYYRNSKACPVVVAVIDQDIGHTLFNVP 2943
Query 2871 GTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPV 2930
T+LR LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P
Sbjct 2944 TTVLRY-GFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPH 3002
Query 2931 PYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTC 2989
PYCY V+ + Y SL P RY L + I+FP EG VRVV T YCR G C
Sbjct 3003 PYCYTGGVMHNASLYSSLAPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLC 3062
Query 2990 ERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVA 3049
E +E G+C + + WVLNN YYR++PG FCG +A +L+ + L++PI ++AS VA
Sbjct 3063 EEAEEGICFNFNRSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALTASSVA 3122
Query 3050 GGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIY 3109
G I+AI+V YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L +Y+ Y
Sbjct 3123 GAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFY 3182
Query 3110 LYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNG 3169
Y T Y +++S + H+QW+VM+ ++P W I Y+ + + H W FS R++
Sbjct 3183 FYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFS--YCRKIGTEV 3240
Query 3170 VSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREA 3229
S TFEE AL TF++ KE Y KL++ V +NRYL+LYNKY+YFSG MDT +YREA
Sbjct 3241 RSDGTFEEMALTTFMITKESYCKLKNSV--SDVAFNRYLSLYNKYRYFSGKMDTAAYREA 3298
Query 3230 ACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTT 3288
AC LAKA+ F+ N+G+DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G
Sbjct 3299 ACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCIVSVTYGNM 3358
Query 3289 TLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNC 3348
TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R ++ +F V +G + L V+ + MQ C
Sbjct 3359 TLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSGRMSLTVMSYQMQGC 3418
Query 3349 VLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSC 3408
L L V NP TPKY F ++PG+TF+VLA YNG P G + +R + TIKGSFL GSC
Sbjct 3419 QLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVTLRSSHTIKGSFLCGSC 3478
Query 3409 GSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVL 3468
GSVG+ + D V F YMH +EL TG H GTD GNFYGP+ D Q Q D T TVNV+
Sbjct 3479 GSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVV 3538
Query 3469 AWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMC 3528
AWLYAA+ N WF+ + +L +FN+ AM + + D V L L++ TG+ V +
Sbjct 3539 AWLYAAIFNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVL 3596
Query 3529 ASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTIL 3588
A++K L +G G+ ILGS +LEDE TP DV +Q +GV QS R IKGT W+L +
Sbjct 3597 AAIKRL-HSGFQGKQILGSCVLEDE-TPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTF 3654
Query 3589 TSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVA 3648
++ +W++F ++ + L + + +FAM+ +KHKH +L ++++P L T
Sbjct 3655 LFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLIKHKHLYLTMYIMPVLCTFY 3713
Query 3649 YFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRV 3708
+V S+ WL ++ + + + +V ++ +T R++ D +
Sbjct 3714 TNYLVVYKQSFRGLAYAWLSHFVPAVDYTYMDEVLYGVVLLVAMVFVTMRSINHDVFSIM 3773
Query 3709 WTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPI 3768
+ + +++LV Y+G L++ + ++ + S+ Y+ + A+ ++ + +
Sbjct 3774 FLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTWTTMLSLATAK-VIAKWLAVNVL 3830
Query 3769 FFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGL 3828
+F ++ ++L Y +GY C CY+G+ LLN FR+ LGVY+Y +S QE RYMN+ GL
Sbjct 3831 YFTDVPQIKLVLLSYLCIGYVCCCYWGILSLLNSIFRMPLGVYNYKISVQELRYMNANGL 3890
Query 3829 LPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLW 3888
PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+SKLW
Sbjct 3891 RPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNSKLW 3950
Query 3889 AQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQ 3942
C LHN+IL D + AF+K+ LL VL + AVD I ++ ++ + + LQ
Sbjct 3951 QYCSTLHNEILATSDLSMAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNTVLQ 4010
Query 3943 AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL 4001
A+ SEF ++ S+ + A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ RKL
Sbjct 4011 ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL 4070
Query 4002 EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI 4061
E+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN
Sbjct 4071 ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA 4130
Query 4062 IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN 4121
IP T+ L +++PD + D TYA +W IQ + DAD + QL+EI +++
Sbjct 4131 IPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDVNS--- 4187
Query 4122 LAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGR 4179
WPL++ A R N S V LQNNEL P LR +G+ T YYNTT G+
Sbjct 4188 -TWPLVIAANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQ--CYYNTTGTGK 4244
Query 4180 FVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNR 4239
V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L R
Sbjct 4245 IVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNTLAR 4303
Query 4240 GMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLC 4299
G V+G+L++TVRLQAG ATE +NS +LS CAF+VD K Y DY+ GG P+TNCVKMLC
Sbjct 4304 GWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIKQGGVPVTNCVKMLC 4363
Query 4300 THTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCAND 4359
H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P D
Sbjct 4364 DHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-IKD 4422
Query 4360 PVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTGT 4418
PV + L + VC VCG W+ CSC QS D +FLNR+ G S ARL PC +G
Sbjct 4423 PVSYVLTHDVCQVCGFWRDGSCSCVGT-GSQFQSKDT-NFLNRIRGTSVNARLVPCASGL 4480
Query 4419 STDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETI 4478
TDV RAFDI N AG + K NCCRFQ DED N +D +FVVKR Y E+
Sbjct 4481 DTDVQLRAFDICNANRAGIGLYYKVNCCRFQRVDEDGNKLDKFFVVKRTNLEVYNKEKEC 4540
Query 4479 YNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEIL 4538
Y L K+C VA+H+FF F ++G VPHI R+ L+K+TM DL YALRHFD +C TLKEIL
Sbjct 4541 YELTKECGVVAEHEFFTFDVEGSRVPHIVRKDLSKFTMLDLCYALRHFDRNDCSTLKEIL 4600
Query 4539 VTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLT 4598
+TY C++ YF KKDWYDFVENPDI+ VY LG +ALL T +F DA+ AG+VGVLT
Sbjct 4601 LTYAECEESYFQKKDWYDFVENPDIINVYKKLGPIFNRALLNTAKFADALVEAGLVGVLT 4660
Query 4599 LDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYI 4658
LDNQDL G WYDFGDF++T PG GV V DSYYS +MP+LT+ AL +E V+ Y
Sbjct 4661 LDNQDLYGQWYDFGDFVKTVPGCGVAVADSYYSYMMPMLTMCHALDSELFVN----GTYR 4716
Query 4659 KWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSF 4718
++DL++YDFT+ +L+LF +YFK+W TYHPN C DDRCI+HCANFN+LFS V P T F
Sbjct 4717 EFDLVQYDFTDFKLELFTKYFKHWSMTYHPNTCECEDDRCIIHCANFNILFSMVLPKTCF 4776
Query 4719 GPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGN 4778
GPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+LL+YAADPA+H AS +
Sbjct 4777 GPLVRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYRLSLKDLLLYAADPALHVASAS 4836
Query 4779 LLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDG 4838
LLD RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +SKG KEGSSV+LKHFFF QDG
Sbjct 4837 ALLDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSVDLKHFFFTQDG 4896
Query 4839 NAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPF 4898
NAAI+DY+YY+YNLPTM DI+QLLFV+EVV+KYF+ Y+GGCI A QVIVNN DKSAG+PF
Sbjct 4897 NAAITDYNYYKYNLPTMVDIKQLLFVLEVVNKYFEIYEGGCIPATQVIVNNYDKSAGYPF 4956
Query 4899 NKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTM 4958
NK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI STM
Sbjct 4957 NKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILSTM 5016
Query 4959 TNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAM 5018
T R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPKCDRAM
Sbjct 5017 TGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPKCDRAM 5076
Query 5019 PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDAT 5078
PN+LRI++SLVLARKH +CCS + RFYRLANECAQVLSE+VMCGG YVKPGGTSSGDAT
Sbjct 5077 PNILRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLSEIVMCGGCYYVKPGGTSSGDAT 5136
Query 5079 TAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFY 5138
TA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD FV+E+Y
Sbjct 5137 TAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVSEYY 5196
Query 5139 AYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLT 5198
+L KHFSMMILSDD VVC+NS +AS+G +A+I F+ VLYYQNNVFMSEAKCW ETD+
Sbjct 5197 EFLNKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQVLYYQNNVFMSEAKCWVETDIE 5256
Query 5199 KGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDA 5258
KGPHEFCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFVSLAIDA
Sbjct 5257 KGPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFVSLAIDA 5316
Query 5259 YPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYT 5318
YPL H N EY +VF +YL+YI+KL+++L +LD YSV+L+ + ++ + FY+ MY
Sbjct 5317 YPLVYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSYSVILSTCDGQKFTDETFYKNMYL 5376
Query 5319 PHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPG 5378
VLQ+VGACV+C+SQTSLRCG+CIR+P LCCKC YDHV+ST HK VLSV+PYVCN+PG
Sbjct 5377 RSAVLQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVLSVSPYVCNSPG 5436
Query 5379 CDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDW 5438
CDV DVT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS + DFN IA+C W
Sbjct 5437 CDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYIEDFNKIASCKW 5496
Query 5439 TNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRP 5498
T DY+LAN CTERLKLFAAET KATEE FK Y AT+RE++SDREL LSWE+GK RP
Sbjct 5497 TEVDDYVLANECTERLKLFAAETQKATEEAFKQCYASATIREIVSDRELILSWEIGKVRP 5556
Query 5499 PLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMP 5558
PLN+NYVFTGY T N K +GEY F+K + + V YR TTTYKL+VGD F+LTSH V
Sbjct 5557 PLNKNYVFTGYHFTNNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFILTSHAVSS 5616
Query 5559 LSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFA 5616
LSAPTLVPQE+Y +R +Y ++ + F +NV NYQ +GM++Y T+QGPPGTGKSH A
Sbjct 5617 LSAPTLVPQENYTSIRFASVY---SVPETFQNNVPNYQHIGMKRYCTVQGPPGTGKSHLA 5673
Query 5617 IGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTL 5676
IGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RV+C+DKFKVN T
Sbjct 5674 IGLAVYYCTARVVYTAASHAAVDALCEKAHKFLNINDCTRIVPAKVRVDCYDKFKVNDTT 5733
Query 5677 EQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLL 5736
+YVF T+NALPE DI+V DE+SM TNY+LSV+N+R+RAKHYVYIGDPAQLPAPR LL
Sbjct 5734 RKYVFTTINALPELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGDPAQLPAPRVLL 5793
Query 5737 TKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCF 5796
KGTLEP YFNSV +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA D S+ CF
Sbjct 5794 NKGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYNNKLKAKNDNSSMCF 5853
Query 5797 KMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQT 5856
K++YKG TH+ SSA+N QI ++ +FL NP+W AVFISPYNSQN VA ++LGL TQT
Sbjct 5854 KVYYKGQTTHESSSAVNMQQIHLISKFLKANPSWSNAVFISPYNSQNYVAKRVLGLQTQT 5913
Query 5857 VDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEI 5916
VDS+QGSEYD+VI++QT ETAHS NVNRFNVAITRAK GILC+MS L++ L FT+L +
Sbjct 5914 VDSAQGSEYDFVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSSMQLFESLNFTTLTL 5973
Query 5917 PRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDMT 5975
+ N LQ T LFKDCS+ G HP AP+ L+VD K+K G L V + +T
Sbjct 5974 DKINNPRLQ--CTTNLFKDCSRSYVGYHPAHAPSFLAVDDKYKVGGDLAVCLNVADSAVT 6031
Query 5976 YRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLG 6035
Y RLIS+MGFK++ ++GY +FITR+EAI+ VRAW+GFD EG HA R+++GTN PLQLG
Sbjct 6032 YSRLISLMGFKLDLTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHAIRDSIGTNFPLQLG 6091
Query 6036 FSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQML 6095
FSTG++ V TG + F + +A+ PPG+QFKHLIPLM +G W+VVRI+IVQML
Sbjct 6092 FSTGIDFVVEATGMFAERDGYVFKKAAARAPPGEQFKHLIPLMSRGQKWDVVRIRIVQML 6151
Query 6096 SDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHS 6155
SD L +L+D VV V WA FELT ++YF K+G E C +C +RATCF++ + Y CW HS
Sbjct 6152 SDHLVDLADSVVLVTWAASFELTCLRYFAKVGREVVCSVCTKRATCFNSRTGYYGCWRHS 6211
Query 6156 IGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRV 6215
DY+YNP ++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+CF K V
Sbjct 6212 YSCDYLYNPLIVDIQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRCLAVHDCFCKSV 6271
Query 6216 DWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKF 6275
+W +EYPII +E+ +N +CR +Q ++ +AA+L +++ V +DIGNPK + CV D +KF
Sbjct 6272 NWNLEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKGYD--FKF 6329
Query 6276 YDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLN 6335
YDA P +++ Y Y H D+F DG+C+FWNCNVD+YPAN++VCRFDTRVL+ LN
Sbjct 6330 YDASPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLNKLN 6386
Query 6336 LPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKS 6395
LPGC+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD+PC +DYVPL+S
Sbjct 6387 LPGCNGGSLYVNKHAFHTSPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLRS 6446
Query 6396 ATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLE 6455
ATCITRCNLGGAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFTRLQSLE
Sbjct 6447 ATCITRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQSLE 6506
Query 6456 NVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNI 6515
NV +N+VN GHFDG+ GE+P ++I V K+ DV +F+N T P NVA EL+AKR+I
Sbjct 6507 NVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAKRSI 6566
Query 6516 KPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFF 6575
+P PE+K+ NL +D+ + V+WDY +D+ ST VC TD+ L V F
Sbjct 6567 RPHPELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVCKYTDL------QCIESLNVLF 6620
Query 6576 DGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI---GEAVKTQFNYYK 6632
DGR +G ++ F+ RNGV I +K L GP++A LNGV + V+ F K
Sbjct 6621 DGRDNGALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFAVRK 6680
Query 6633 KVDGVVQQLP-------------------------------ETYFTQSRNLQEFKPRSQM 6661
D V+ T FTQSR L F PRS+M
Sbjct 6681 DGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRLLSSFTPRSEM 6740
Query 6662 EIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFI 6721
E DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHLLIGLA+R ++S +++F+
Sbjct 6741 EKDFMDLDDDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRQQKSNLVIQEFV 6800
Query 6722 PMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISF 6781
DS++ +YFITD +GSSK VC+VIDLLLDDFV+I+KS +L VSKVV V +D+ + F
Sbjct 6801 TYDSSIHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKSLNLKCVSKVVNVNVDFKDFQF 6860
Query 6782 MLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMN 6841
MLWC + V TFYP+LQ++ W+PG MP LYK LE+ +L NYG TLP G MMN
Sbjct 6861 MLWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPLERVNLWNYGKPITLPTGCMMN 6920
Query 6842 VAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDF 6901
VAKYTQLCQYL+T TLAVP NMRV+H GAGSDKGVAPG+AVLRQWLP G++LVD+D+N F
Sbjct 6921 VAKYTQLCQYLSTTTLAVPANMRVLHLGAGSDKGVAPGSAVLRQWLPAGSILVDNDVNPF 6980
Query 6902 VSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLAL 6961
VSD+ ++ G+C T+ +WDLIISDMYDP TKN+ + N SK+GFFTY+C I+ KLAL
Sbjct 6981 VSDSVASYYGNCITLPFDCQWDLIISDMYDPLTKNIGEYNVSKDGFFTYLCHLIRDKLAL 7040
Query 6962 GGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYV 7021
GGSVAIKITE SWNA+LY LMG FA+WT F TNVNASSSE FLIG N+L K R +IDG
Sbjct 7041 GGSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWLNKTRTEIDGKT 7100
Query 7022 MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIR 7081
MHANY+FWRN+ +YSLFDMSKFPLK GTAV+SLK QIND++LSL+ KG+L++R
Sbjct 7101 MHANYLFWRNSTMWNGGAYSLFDMSKFPLKAAGTAVVSLKPDQINDLVLSLIEKGKLLVR 7160
Query 7082 ENNRVVISSDVLVN 7095
+ + V D LVN
Sbjct 7161 DTRKEVFVGDSLVN 7174
Score = 608 bits (1567), Expect = 5e-172, Method: Composition-based stats.
Identities = 234/1124 (21%), Positives = 405/1124 (36%), Gaps = 202/1124 (18%)
Query 2 ESLVPGFNEKTHVQLS---LPVLQ-------VRDVLVRGFGDSVEEVLSEARQHLKDGTC 51
E V G HV+++ LP L+ +RD+ V + ++V + L+ G+
Sbjct 46 EPKVKGKTLVNHVRVNCSRLPALECCVQSAIIRDIFV---DEDPQKVEASTMMALQFGSA 102
Query 52 GLVEVEK----------GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQY 97
LV+ K GVLP+ +F + T HV L + +G+
Sbjct 103 VLVKPSKRLSIQAWTNLGVLPKTAAMGLFKRVCLCNTRECSCDAHVAFHLFTVQPDGVCL 162
Query 98 GRSGETLGVLVPHVGEIPVAYRK------VLLRKNGNKGA---GGHSYGADLKSFDLGDE 148
G +G +G VP V IP ++ +LLRK GNKG+ G + +D E
Sbjct 163 G-NGRFIGWFVP-VTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE 220
Query 149 LGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARA 208
D E+ N K+S L++ G +VD C G C+ L
Sbjct 221 ---DACEEVHLNPKGKYSCK-AYALLKGYRGVKPILFVDQYGCDYTG----CLAKGLEDY 272
Query 209 GKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKS-YELQTPFEIKLAKKFDTFN 267
G TLSE + R + E +AW+ +R ++ LQT ++
Sbjct 273 GDL--TLSEMKELFPVWRDSL---DSEVLVAWHVDRDPRAAMRLQTLATVRCIDYVGQPT 327
Query 268 GEC---------PNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLS 318
+ P + N+I+K + PR+ + L Y EC +
Sbjct 328 EDVVDGDVVVREPAHLLAANAIVKRL-PRLVETMLYTDSSVTEFCYKTK-LCECGFITQF 385
Query 319 TLMKC--DHCGETSWQTGDFVKATCE-FCGTENLTKE-GATTCGYLPQNAVVKIYCPACH 374
+ C D C W G+ + C + E A + G +P+ V+
Sbjct 386 GYVDCCGDTCDFRGWVAGNMMDGFPCPGCTKNYMPWELEAQSSGVIPEGGVL-------- 437
Query 375 NSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI--- 431
+ + ++ G + FG V+ + C W+P +++
Sbjct 438 ---------FTQSTDTVNRESFKLYGHAVVPFGSAVY-WSPCPG---MWLPVIWSSVKSY 484
Query 432 -GCNHTGVVGEGS-EGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVE 489
G +TGVVG + D + L + V + G+ E+ AI+
Sbjct 485 SGLTYTGVVGCKAIVQETDAICRSLYMDYVQ-HKCGNL---EQRAIL------------- 527
Query 490 TVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSIFS 549
GLD +Q++ + G++ + +L + F R+ F+
Sbjct 528 ---GLDDVYHRQLLVNRGDYSL-----------------LLENVDLFVKR-----RAEFA 562
Query 550 RTLETAQNSVRVLQKAAITILDGISQYSLRLIDA-MMFTSDLA------TNNLVVMAYIT 602
T + + L +LDG+ S LI + FTS + T+ + MA +
Sbjct 563 CKFATCGDGLVPL------LLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMALLF 616
Query 603 GGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRD------GWEIVKFISTCA 656
V++ ++++ + G + + K + + K E + D GW + ++
Sbjct 617 MHDVKVATKYVKKVTGKLAVRFKALGVAVVRKITEWFDLAVDIAASAAGWLCYQLVN--G 674
Query 657 CEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII---IGGAKLKALNLGETFVTHS 713
V ++T +E+ E V+ F F + DS+ + G + + S
Sbjct 675 LFAVANGVITFVQEVPELVKNFVDKFKAFFKVLIDSMSVSILSGLTVVKTASNRVCLAGS 734
Query 714 KGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEA 773
K +Y + + +MP+ E L GE P + V + L
Sbjct 735 K-VYEVVQ--KSLSAYVMPVGC-SEATCLVGEIEPAVFEDDVVDVVKAPLT-----YQGC 785
Query 774 VEAPLVGTPVCINGLMLLEIKDTEKYCALAPN-MMVTNNTFTLKGGAPTKVTFGDDT-VI 831
+ P +CI + + + Y + N + + A KV F D V
Sbjct 786 CKPPTSFEKICIVDKLYMAKCGDQFYPVVVDNDTVGVLDQCWRFPCAGKKVEFNDKPKVR 845
Query 832 EVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE--- 888
++ + + ITF LD D VL++ CS + V+ ++E VV DAV TL P E
Sbjct 846 KIPSTRKIKITFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEHDV 905
Query 889 LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYE 948
+ T + LD + YLFDE G+ +A MYCSF PD++ DC + + + +
Sbjct 906 IGTKVCALLDRLAGDYVYLFDEGGDEVIAPRMYCSFSAPDDE----DCVAADVVDADENQ 961
Query 949 YGTEDDYQGKPLEFGATSAALQPEEEQEED-----WLDDDSQQTVGQQDGSEDNQTTTIQ 1003
+D +A+ + QEED ++ DS+ V E+
Sbjct 962 DDDAED------------SAVLVADTQEEDGVAKGQVEADSEICVAHTGSQEE------- 1002
Query 1004 TIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVE 1047
+ E + EV S + + AD V+
Sbjct 1003 -LAEPDAVGSQTPIASAEETEVGEASDREGIAEAKATVCADAVD 1045
Score = 226 bits (576), Expect = 8e-57, Method: Composition-based stats.
Identities = 65/252 (26%), Positives = 116/252 (46%), Gaps = 18/252 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV D+++ + V V+VN AN + HG GVAGA+ + +A E+ D +
Sbjct 1319 CITPNVCFVKGDVIKVVRLVNAEVIVNPANGRMAHGAGVAGAIAEKAGSAFIKETSDMVK 1378
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHEVLLAPLLS 1150
G +VG +G L K L++VGP+ + LL+ AY++ N+ + ++ L+S
Sbjct 1379 AQGVCQVGECYESAGGKLCKKVLNIVGPDARGHGKQCYSLLERAYQHINKCDNVVTTLIS 1438
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + V NV L +++ +D + + K + ++A+
Sbjct 1439 AGIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFDVIEKCQVTSVAGTKALSLQLAKNLCR 1498
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+VK F+T + S+ ++C L+E + L ++ L ++ N +
Sbjct 1499 DVK-FVTNACSSLFS--------ESCFVSSYDVLQEVEALRHDIQLDDDARVFVQANMDC 1549
Query 1264 HPDSATLVSDID 1275
P LV+ D
Sbjct 1550 LPTDWRLVNKFD 1561
Score = 47.4 bits (111), Expect = 0.007, Method: Composition-based stats.
Identities = 32/149 (21%), Positives = 58/149 (39%), Gaps = 16/149 (11%)
Query 1663 GLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV 1722
G S NC+L + L+ +Q + L+F +Q + +AG F ++ K++
Sbjct 1110 GFYSPAIERTNCWLRSTLIVMQSLPLEFKDLEMQKLWLSYKAGYDQCFVDKLVKSVPKSI 1169
Query 1723 GEL--GDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFK 1780
G V + + S K N C C + L+G++A+ + G +
Sbjct 1170 ILPQGGYVADFAYFFLSQ---CSFKAYANWRCLECDM-ELKLQGLDAMFFYGDV------ 1219
Query 1781 KGVQIPCTCGKQATKYLVQQESPFVMMSA 1809
V C CG T L+ + P+ +
Sbjct 1220 --VSHMCKCGNSMT--LLSADIPYTLHFG 1244
>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180
Score = 7919 bits (20548), Expect = 0.0, Method: Composition-based stats.
Identities = 2741/5713 (48%), Positives = 3667/5713 (64%), Gaps = 216/5713 (4%)
Query 1513 DWSYSGQ-STQLGIEFLKR----GDKSVYYTSNPTTFHLDG--EVITFDNLKTLLSLREV 1565
DW + + G+ +K G+ V + +G + + ++ LL+
Sbjct 1552 DWRLVNKFDSVDGVRTIKYFECPGEVFVSSQGKKFGYVQNGSFKEASVSQIRALLA---- 1607
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ V TVD +N + V +G+ G + DG +VTK++ H+GK F+
Sbjct 1608 NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIHKGKVFFQYSGLS 1667
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A + D L +Y S L KW + K ++NNCY+ A L LQ
Sbjct 1668 AADLAAVKDAFGFDEPQLLQYYSMLGMC-KWPVVVCGNYFAFKQSNNNCYINVACLMLQH 1726
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
+ LKF + R+G+ F +L+LA + E D + + + A+L
Sbjct 1727 LSLKFPKWQWRRPGNEFRSGKPLRFVSLVLAKGSFKFNEPSDSTDFIRVELREADLSGAT 1786
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
L +CK CG +Q KGV+AVM+ GTL KG I CTCG + + Q PF+
Sbjct 1787 CDLEFICK-CGVKQEQRKGVDAVMHFGTLDKSGLVKGYNIACTCGDKLV-HCTQFNVPFL 1844
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ +TG GHY H+ K D ++K SE KG TD
Sbjct 1845 ICSNTPEGKKLPDDV-VAANIFTGG-SVGHYTHVKCKPKYQLYDACNVSKVSEAKGNFTD 1902
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPN-- 1922
Y +N T + TY LD V C P L YY + Y+T +PI + +
Sbjct 1903 CLYLKNLKQTFSSVLTTYYLDDVKCVAYKPDLSQYYCESGKYYT-KPIIKAQFRTFEKVE 1961
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I A+ LN G+ E K+T +P GDVV Y +
Sbjct 1962 GVYTNFKLVGHDI--AEKLNAKLGFDCNSPFMEYKITEWPTATGDVVLASDDLYVSRYSG 2019
Query 1982 GAKLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVETSNSFD----------- 2026
G KP++W H + TY +P+ C ++ PV+ S D
Sbjct 2020 GCVTFGKPVIWRGHEEASLKSLTYFNRPSVVC-ENKFNVLPVDVSEPTDRRPVPSAVLVT 2078
Query 2027 ---------VLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVG---- 2073
+ +E + AC V +++V + V VK ++ G
Sbjct 2079 GAASGADASAISTEPGTAKEQKACAS-DSVEDQIVMEAQKKSSVTTVAVKEVKLNGVKKP 2137
Query 2074 -----DIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATH--- 2125
+++ + K+ + + D+ ++ + NELSR++ T+ +
Sbjct 2138 VKWNCSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWTANELSRLINSPTVREYVKW 2197
Query 2126 GLAAVNSVPWDTIAN--YAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFT 2183
G++ + +P + + + F+ V I C + +F F
Sbjct 2198 GMSKL-IIPANLLLLRDEKQEFVAPKVVKAKAIA-------CYGAVKWFLLYCFSWIKF- 2248
Query 2184 RSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLIN--------IIIWF-- 2233
N+ K T +A K K C A N L++ N+S + ++WF
Sbjct 2249 ---NTDNKVIYTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVFLLWFNF 2302
Query 2234 LLLSVCLGSL---------IYSTAALGVLMSNLGMPSYCTGYRE---GYLNSTNVTIATY 2281
L +V L ++ + + + G+ + C Y+ GY +S +
Sbjct 2303 LYANVILSDFYLPNIGPLPMFVGQIVAWVKTTFGVLTICDFYQVTDLGYRSS-------F 2355
Query 2282 CTGSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLTAFGLVAEWFLAYILFTRFF 2338
C GS+ C +C SG D LD Y S+ +Q + SF + ++ F LV E + Y L+T F
Sbjct 2356 CNGSMVCELCFSGFDMLDNYESINVVQHVVDRRVSFDY-ISLFKLVVELVIGYSLYTVCF 2414
Query 2339 YVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKS 2396
Y L + MQL ++ F+ + W L + + M P ++R YI + Y V+
Sbjct 2415 YPLFVLVGMQLLTTWLPEFFMLGTMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVYCL 2474
Query 2397 YVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCD 2456
HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC+NC+
Sbjct 2475 CRHVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLNCN 2534
Query 2457 TFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERH 2516
++ G+TFI+ E A DLS + KRP+NPTD + Y V V S+ L++++ GQ+ Y+
Sbjct 2535 SWKPGNTFITHEAAADLSKELKRPVNPTDSAYYSVIEVKQVGCSMRLFYERDGQRVYDDV 2594
Query 2517 SLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQAL 2576
S S FV+++ L + KG +V+V + ++ +++ +A+V+Y+Q + +P+L++++ L
Sbjct 2595 SASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRPMLMVEKKL 2652
Query 2577 VSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISA 2636
++ V+ MFD YV + +V + L + V A L + V L+ V+ TF+
Sbjct 2653 ITTANTGLSVSRTMFDLYVYSLLRHLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFVGC 2712
Query 2637 ARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCS 2695
AR+ +DSDVETK + + + + + +EVT +SCNN + TY K + + DLG I +
Sbjct 2713 ARRKCAIDSDVETKSITKSVMAAVNAGVEVTDESCNNLVPTYVKSDTIVAADLGVLIQNN 2772
Query 2696 ARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVT 2755
A+H+ + VAK+ N+A IW+V F LS L+ ++R A K L KLT V ++T
Sbjct 2773 AKHVQSNVAKAANVACIWSVDAFNQLSADLQHRLRKACVKTGLKIKLTYNKQEANVPILT 2832
Query 2756 TKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGG 2815
T +LKGG + + L+ L L+ V + + P + + K +K ID G
Sbjct 2833 TPFSLKGGAVFSRVLQWLFVANLICFIV---LWALMPTYAVHKSDMQLPLYASFKVIDNG 2889
Query 2816 VTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTI 2873
V RD++ TD CFANK FD W+ G Y N KACP++ AVI +++G + +P +
Sbjct 2890 VLRDVSVTDACFANKFNQFDQWYESTFGLVYYRNSKACPVVVAVIDQDIGHTLFNVPTKV 2949
Query 2874 LRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC 2933
LR LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P PYC
Sbjct 2950 LRY-GFHVLHFITHAFATDRVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHPYC 3008
Query 2934 YDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCERS 2992
Y V+ + Y SL P RY L + I+FP EG VRVV T YCR G CE +
Sbjct 3009 YTEGVMHNASLYSSLVPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLCEEA 3068
Query 2993 EAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGI 3052
E G+C + + WVLNN YYR++PG FCG +A +L+ + L+QPI ++AS VAG I
Sbjct 3069 EEGICFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVQPIDFFALTASSVAGAI 3128
Query 3053 VAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYL 3112
+AI+V YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L +Y+ Y Y
Sbjct 3129 LAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFYT 3188
Query 3113 TFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSF 3172
T Y +++S + H+QW+VM+ ++P W I Y+ + + H W FS R++ + S
Sbjct 3189 TLYFPSEISVVMHLQWLVMYGAIMPLWFCITYVAVVVSNHALWLFS--YCRKIGTDVRSD 3246
Query 3173 STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACC 3232
TFEE AL TF++ KE Y KL++ V +NRYL+LYNKY+YFSG MDT +YREAAC
Sbjct 3247 GTFEEMALTTFMITKESYCKLKNSV--SDVAFNRYLSLYNKYRYFSGKMDTATYREAACS 3304
Query 3233 HLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLN 3291
LAKA+ F+ N+G+DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G TLN
Sbjct 3305 QLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCVVSVTYGNMTLN 3364
Query 3292 GLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLK 3351
GLWLDD VYCPRHVIC+S DM +P+Y +LL R ++ +F V + + L V+ + MQ +L
Sbjct 3365 GLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSDRMSLTVMSYQMQGSLLV 3424
Query 3352 LKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSV 3411
L V NP TPKY F ++PG+TF+VLA YNG P G + MR + TIKGSFL GSCGSV
Sbjct 3425 LTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVVMRSSHTIKGSFLCGSCGSV 3484
Query 3412 GFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWL 3471
G+ + D V F YMH +EL TG H GTD GNFYGP+ D Q Q D T TVNV+AWL
Sbjct 3485 GYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAWL 3544
Query 3472 YAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASL 3531
YAA++N WF+ + +L +FN+ AM + + D V L L++ TG+ V + A++
Sbjct 3545 YAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVLAAI 3602
Query 3532 KELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSL 3591
K L +G G+ ILGS +LEDE TP DV +Q +GV QS R IKGT W+L +
Sbjct 3603 KRL-HSGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTFLFC 3661
Query 3592 LVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN 3651
++ +W++F ++ + L + + FAM+ +KHKH +L ++++P L T+ Y N
Sbjct 3662 SIISAFVKWTMFMYVTTH-MLGVTLCALCFVIFAMLLIKHKHLYLTMYIMPVLCTLFYTN 3720
Query 3652 MVY--MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVW 3709
+ S+ WL ++ + + + +V ++ +T R++ D ++
Sbjct 3721 YLVVGYKQSFRGLAYAWLSYFVPAVDYTYMDEVLYGVVLLVAMVFVTMRSINHDVFSTMF 3780
Query 3710 TLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIF 3769
+ +++LV Y+G L++ + ++ + S+ Y+ + A+ ++ + ++
Sbjct 3781 LVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTWTTMLSLATAK-VIAKWLAVNVLY 3837
Query 3770 FITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL 3829
F ++ ++L Y +GY C CY+G+ LLN FR+ LGVY+Y +S QE RYMN+ GL
Sbjct 3838 FTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISVQELRYMNANGLR 3897
Query 3830 PPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA 3889
PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+SKLW
Sbjct 3898 PPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNSKLWQ 3957
Query 3890 QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQA 3943
C LHN+IL D + AF+K+ LL VL + AVD I ++ ++ + + LQA
Sbjct 3958 YCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNTVLQA 4017
Query 3944 IASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLE 4002
+ SEF ++ S+ + A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ RKLE
Sbjct 4018 LQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKLE 4077
Query 4003 KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII 4062
+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN I
Sbjct 4078 RMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAI 4137
Query 4063 PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL 4122
P T+ L +++PD + D TYA +W IQ + DAD + QL+EI +++
Sbjct 4138 PPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDVNS---- 4193
Query 4123 AWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRF 4180
WPL+++A R N S V LQNNEL P LR +G+ YYNTT G+
Sbjct 4194 TWPLVISANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNIPTQ--CYYNTTGTGKI 4251
Query 4181 VLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRG 4240
V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG
Sbjct 4252 VYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNTLARG 4310
Query 4241 MVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCT 4300
V+G+L++TVRLQAG ATE +NS +LS CAF+VD K Y DY+ GG P+TNCVKMLC
Sbjct 4311 WVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIQQGGVPVTNCVKMLCD 4370
Query 4301 HTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDP 4360
H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DP
Sbjct 4371 HAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-IKDP 4429
Query 4361 VGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTGTS 4419
V + L + VC VCG W+ CSC QS D +FLNRV G S ARL PC +G
Sbjct 4430 VSYVLTHDVCQVCGFWRDGSCSCVGT-GSQFQSKDT-NFLNRVRGTSVNARLVPCASGLD 4487
Query 4420 TDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIY 4479
TDV RAFDI N AG + K NC RFQ DE+ N +D +FVVKR Y E+ Y
Sbjct 4488 TDVQLRAFDICNANRAGIGLYYKVNCFRFQRVDEEGNKLDKFFVVKRTNLEVYNKEKECY 4547
Query 4480 NLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILV 4539
L KDC VA+H+FF F ++G VPHI R+ L+K+TM DL YALRHFD +C TLKEIL+
Sbjct 4548 ELTKDCGVVAEHEFFTFDVEGSRVPHIVRKDLSKFTMLDLCYALRHFDRNDCSTLKEILL 4607
Query 4540 TYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTL 4599
TY CD+ YF KKDWYDFVENPDI+ VY LG +ALL T F D + AG+VGVLTL
Sbjct 4608 TYAECDESYFQKKDWYDFVENPDIINVYKKLGPIFNRALLNTANFADTLVEAGLVGVLTL 4667
Query 4600 DNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIK 4659
DNQDL G WYDFGDF++T P GV V DSYYS +MP+LT+ AL +E V+ Y +
Sbjct 4668 DNQDLYGQWYDFGDFVKTVPCCGVAVADSYYSYMMPMLTMCHALDSELFVN----GTYRE 4723
Query 4660 WDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFG 4719
+DL++YDFT+ +L+LF++YFK+W TYHPN C DDRCI+HCANFN+LFS V P T FG
Sbjct 4724 FDLVQYDFTDFKLELFNKYFKHWSMTYHPNTSECEDDRCIIHCANFNILFSMVLPKTCFG 4783
Query 4720 PLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNL 4779
PLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+LL+YAADPA+H AS +
Sbjct 4784 PLVRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYRLSLKDLLLYAADPALHVASASA 4843
Query 4780 LLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGN 4839
LLD RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +SKG KEGSSV+LKHFFF QDGN
Sbjct 4844 LLDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSVDLKHFFFTQDGN 4903
Query 4840 AAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFN 4899
AAI+DY+YY+YNLPTM DI+QLLFVVEVV+KYF+ Y+GGCI A QVIVNN DKSAG+PFN
Sbjct 4904 AAITDYNYYKYNLPTMVDIKQLLFVVEVVNKYFEIYEGGCIPATQVIVNNYDKSAGYPFN 4963
Query 4900 KWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMT 4959
K+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI STMT
Sbjct 4964 KFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILSTMT 5023
Query 4960 NRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMP 5019
R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPKCDRAMP
Sbjct 5024 GRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPKCDRAMP 5083
Query 5020 NMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATT 5079
N+LRI++SLVLARKH +CCS + RFYRLANECAQVL E+VMCGG YVKPGGTSSGDATT
Sbjct 5084 NILRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLGEIVMCGGCYYVKPGGTSSGDATT 5143
Query 5080 AYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYA 5139
A+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD FV+E+Y
Sbjct 5144 AFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVSEYYE 5203
Query 5140 YLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTK 5199
+L KHFSM+ILSDD VVC+NS +AS+G +A+I +F+ VLYYQNNVFMSEAKCW ETD+ K
Sbjct 5204 FLNKHFSMIILSDDGVVCYNSEFASKGYIANISDFQQVLYYQNNVFMSEAKCWVETDIEK 5263
Query 5200 GPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAY 5259
GPHEFCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFVSLAIDAY
Sbjct 5264 GPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFVSLAIDAY 5323
Query 5260 PLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTP 5319
PL H N EY +VF +YL+YI+KL+++L +LD SV+L+ + ++ + FY+ MY
Sbjct 5324 PLVYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSISVILSTCDGQKFTDETFYKNMYLR 5383
Query 5320 HTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGC 5379
V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC YDHV+ST HK VLSV+PYVCN+PGC
Sbjct 5384 SAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVLSVSPYVCNSPGC 5443
Query 5380 DVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWT 5439
DV DVT+LYLGGMSYYC++HKP SF L NG VFGLYK +C GS + DFN IA+C WT
Sbjct 5444 DVNDVTKLYLGGMSYYCEAHKPQYSFKLVMNGMVFGLYKQSCTGSPYIEDFNKIASCKWT 5503
Query 5440 NAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPP 5499
DY+LAN CTERLKLFAAET KATEE FK Y AT+RE++SDREL LSWE+GK RPP
Sbjct 5504 EVDDYVLANECTERLKLFAAETQKATEEAFKQCYASATIREIVSDRELILSWEIGKVRPP 5563
Query 5500 LNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPL 5559
LN+NYVFTGY T N K +GEY F+K + + V YR TTTYKL+VGD F+LTSH V L
Sbjct 5564 LNKNYVFTGYHFTNNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFILTSHAVSSL 5623
Query 5560 SAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAI 5617
SAPTLVPQE+Y VR Y ++ + F +NV NYQ +G+++Y T+QGPPGTGKSH AI
Sbjct 5624 SAPTLVPQENYTSVRFASAY---SVPETFQNNVPNYQHIGIKRYCTVQGPPGTGKSHLAI 5680
Query 5618 GLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLE 5677
G A+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RV+C+DKF VN T
Sbjct 5681 GHAVYYCTARVVYTAASHAAVDALCEKAHKFLNINDCARIVPAKLRVDCYDKFNVNDTTR 5740
Query 5678 QYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLT 5737
+YVF T+NALPE DI+V DE+SM TNY+LSV+N+R+RAKHYVYIGDPAQLPAPR LL
Sbjct 5741 KYVFTTINALPELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGDPAQLPAPRVLLN 5800
Query 5738 KGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFK 5797
KGTLEP YFNSV +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA D SA CFK
Sbjct 5801 KGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYNNKLKAKNDNSAMCFK 5860
Query 5798 MFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTV 5857
++YKG TH+ SSA+N QI ++ + L NP+W AVFISPYNSQN VA ++LGL TQT
Sbjct 5861 VYYKGQTTHESSSAVNMQQIHLISKLLKANPSWSNAVFISPYNSQNYVAKRVLGLQTQTA 5920
Query 5858 DSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIP 5917
DS+QGS YD+VI++QT +TAHS NVNRFNVAITRAK GILC+MS L FT+L +
Sbjct 5921 DSAQGSAYDFVIYSQTAQTAHSVNVNRFNVAITRAKKGILCVMSSMQLIGVFNFTTLTLD 5980
Query 5918 RRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDMTY 5976
+ N LQ T LFKDCSK G+ P L+VD K+K G L V + +TY
Sbjct 5981 KINNPRLQ--CTTNLFKDCSKSYVGIPP--CAFLLAVDDKYKVSGNLAVCLNVADSAVTY 6036
Query 5977 RRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGF 6036
RLIS+MGFK++ ++GY +FITR+EAI+ VRAW+GFD EG HATR+++GTN PLQLGF
Sbjct 6037 SRLISLMGFKLDLTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHATRDSIGTNFPLQLGF 6096
Query 6037 STGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLS 6096
STG++ V TG + F + +A+ PPG+QFKHL+PLM +G W+VVRI+IVQMLS
Sbjct 6097 STGIDFVVEATGMFAERDGYVFKKAAARAPPGEQFKHLVPLMSRGQKWDVVRIRIVQMLS 6156
Query 6097 DTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSI 6156
D L +L+D VV V WA FELT ++YF K+G E C +C++RATCF++ + Y CW HS
Sbjct 6157 DHLVDLADSVVLVTWAASFELTCLRYFAKVGKEVVCSVCNKRATCFNSRTGYYGCWRHSY 6216
Query 6157 GFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVD 6216
DY+YNP ++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+CF K V+
Sbjct 6217 SCDYLYNPLIVDIQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRCLAVHDCFCKSVN 6276
Query 6217 WTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFY 6276
W +EYPII +E+ +N +CR +Q ++ +AA+L +++ V +DIGNPK + CV D +KFY
Sbjct 6277 WNLEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKGYD--FKFY 6334
Query 6277 DAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNL 6336
DA P +++ Y Y H D+F DG+C+FWNCNVD+YPAN++VCRFDTRVLS LNL
Sbjct 6335 DASPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLSKLNL 6391
Query 6337 PGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSA 6396
PGC+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD+PC +DYVPL+SA
Sbjct 6392 PGCNGGSLYVNKHAFHTNPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLRSA 6451
Query 6397 TCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLEN 6456
TCITRCNLGGAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFTRLQSLEN
Sbjct 6452 TCITRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQSLEN 6511
Query 6457 VAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIK 6516
V +N+VN GHFDG+ GE+P ++I V K+ DV +F+N T P NVA EL+A+R+I+
Sbjct 6512 VVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAERSIR 6571
Query 6517 PVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFD 6576
P PE+K+ + + + N V+WDY +D+ ST VC TD+ L V FD
Sbjct 6572 PHPELKLFRSSNIHVCWNHVLWDYAKDSVFCSSTYKVCKYTDL------QCIESLNVLFD 6625
Query 6577 GRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI---GEAVKTQFNYYKK 6633
GR +G ++ F+ RNGV I +K L GP++A LNGV + V+ F +
Sbjct 6626 GRDNGALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFAMRRD 6685
Query 6634 VDGVVQQLP-------------------------------ETYFTQSRNLQEFKPRSQME 6662
D V+ T FTQSR L F PRS+ME
Sbjct 6686 GDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRFLSSFSPRSEME 6745
Query 6663 IDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIP 6722
DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHLLIGLA+R K+S +++F+P
Sbjct 6746 KDFMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRPKKSNLVIQEFVP 6805
Query 6723 MDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFM 6782
DS++ +YFITD +GSS+ VC+VIDLLLDDFV+I+KS +L VSKVV V +D+ + FM
Sbjct 6806 YDSSIHSYFITDENSGSSESVCTVIDLLLDDFVDIVKSLNLKCVSKVVNVNVDFKDFQFM 6865
Query 6783 LWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNV 6842
LWC + V TFYP+LQ++ W+PG MP LYK +E+ +L NYG TLP G MMNV
Sbjct 6866 LWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPMERVNLWNYGKPITLPTGCMMNV 6925
Query 6843 AKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFV 6902
AKYTQLCQYL+T TLAVP NMRV+H GAGSDKGVAPG+AVLRQWLP+G++LVD+D+N FV
Sbjct 6926 AKYTQLCQYLSTTTLAVPANMRVLHLGAGSDKGVAPGSAVLRQWLPSGSILVDNDMNPFV 6985
Query 6903 SDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALG 6962
SD+ ++ G+C T+ +WDLIISDMYDP TKN+ + N SK+GFFTY+C I+ KLALG
Sbjct 6986 SDSVASYYGNCITLPFDCQWDLIISDMYDPLTKNIGEYNVSKDGFFTYLCHLIRDKLALG 7045
Query 6963 GSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVM 7022
GSVAIKITE SWNA+LY LMG FA+WT F TNVNASSSE FLIG N+L + R +IDG M
Sbjct 7046 GSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWLNRTRNEIDGKTM 7105
Query 7023 HANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRE 7082
HANY+FWRN+ +YSLFDM+KFPLK GTAV+SLK QIND++LSL+ KG+L++R+
Sbjct 7106 HANYLFWRNSTMWNGGAYSLFDMTKFPLKAAGTAVVSLKPDQINDLVLSLIEKGKLLVRD 7165
Query 7083 NNRVVISSDVLVN 7095
+ V D LVN
Sbjct 7166 TRKEVFVGDSLVN 7178
Score = 622 bits (1604), Expect = 2e-176, Method: Composition-based stats.
Identities = 238/1127 (21%), Positives = 401/1127 (36%), Gaps = 209/1127 (19%)
Query 2 ESLVPGFNEKTHVQLS---LPVLQ-------VRDVLVRGFGDSVEEVLSEARQHLKDGTC 51
E V G HV++ LP L+ +RD+ V + ++V + L+ G+
Sbjct 46 EPKVKGKTLVNHVRVDCSRLPALECCVQSAIIRDIFV---DEDPQKVEASTMMALQFGSA 102
Query 52 GLVEVEK----------GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQY 97
LV+ K GVLP+ +F + T HV +L + +G+
Sbjct 103 VLVKPSKRLSVQAWAKLGVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCL 162
Query 98 GRSGETLGVLVPHVGEIPVAYRK------VLLRKNGNKGA---GGHSYGADLKSFDLGDE 148
G +G +G VP V IP ++ +LLRK GNKG+ G + +D E
Sbjct 163 G-NGRFIGWFVP-VTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE 220
Query 149 LGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARA 208
D E+ N K+S L+R G +VD C G C+ L
Sbjct 221 ---DACEEVHLNPRGKYSCK-AYALLRGYRGVKPILFVDQYGCDYTG----CLAKGLEDY 272
Query 209 GKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKS-YELQTPFEIKLAKKF---- 263
G TLSE + R ++E +AW+ +R ++ LQT ++ +
Sbjct 273 GDL--TLSEMKELSPVWRDSL---DNEVVVAWHVDRDPRAVMRLQTLATVRSIEYVGQPI 327
Query 264 -DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLS 318
D +G+ P + N+I+K + PR+ + L Y +C +
Sbjct 328 EDMVDGDVVMREPAHLLAPNAIVKRL-PRLVETMLYTDSSVTEFCYKTK-LCDCGFITQF 385
Query 319 TLMKC--DHCGETSWQTGDFVKATCE-FCGTENLTKE-GATTCGYLPQNAVVKIYCPACH 374
+ C D CG W G+ + C + E A + G +P+ V+
Sbjct 386 GYVDCCGDTCGFRGWVPGNMMDGFPCPGCCKSYMPWELEAQSSGVIPEGGVL-------- 437
Query 375 NSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVF--SYVGCHNKCAYWVPRASANIG 432
+ + ++ G + FGG + Y G W+P +++
Sbjct 438 ---------FTQSTDTVNRESFKLYGHAVVPFGGAAYWSPYPG------MWLPVIWSSVK 482
Query 433 C----NHTGVVGEGS-EGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAF 487
+TGVVG + D + L + V + G+ E+ AI+
Sbjct 483 SYSYLTYTGVVGCKAIVQETDAICRFLYMDYVQ-HKCGNL---EQRAIL----------- 527
Query 488 VETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSI 547
GLD +Q++ + G++ + +L + F R+
Sbjct 528 -----GLDDVYHRQLLVNRGDYSL-----------------LLENVDLFVKR-----RAE 560
Query 548 FSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA-MMFTSDLAT------NNLVVMAY 600
F+ T + + L +LDG+ S LI + FTS + + + MA
Sbjct 561 FACKFATCGDGLVPL------LLDGLVPRSYYLIKSGQAFTSLMVNFSREVVDMCMDMAL 614
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRD------GWEIVKFIST 654
+ V++ ++++ + G V + K + + K E + D GW + ++
Sbjct 615 LFMHDVKVATKYVKKVTGKVAVRFKALGIAVVRKITEWFDLAVDTAASAAGWLCYQLVN- 673
Query 655 CACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII---IGGAKLKALNLGETFVT 711
V ++T +E+ E V+ F F + DS+ + G + +
Sbjct 674 -GLFAVANGVITFIQEVPELVKNFVDKFKTFFKVLIDSMSVSILSGLTVVKTASNRVCLA 732
Query 712 HSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS 771
SK +Y + +MP+ E L GE P + V + L
Sbjct 733 GSK-VYEVVQ--KSLPAYIMPVGC-SEATCLVGEIEPAVFEDDVVDVVKAPLT-----YQ 783
Query 772 EAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPN-MMVTNNTFTLKGGAPTKVTFGDDT- 829
+ P +CI + + + Y + N + + A KV F D
Sbjct 784 GCCKPPSSFEKICIVDKLYMAKCGDQFYPVVVDNDTVGVLDQCWRFPCAGKKVVFNDKPK 843
Query 830 VIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE- 888
V EV + + I F LD D VL++ CS + V+ ++E VV DAV TL P E
Sbjct 844 VKEVPSTRKIKIIFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEH 903
Query 889 --LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ 946
+ T + L+ YLFDE GE +AS MYCSF PDED C + + +
Sbjct 904 GVIGTKVCALLERLVDDYVYLFDEGGEEVIASRMYCSFSAPDED-----CVATDVVYADE 958
Query 947 YEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWL------DDDSQQTVGQQDGSEDNQTT 1000
+ A + + QEED + DS+ V G E
Sbjct 959 NQD------------DDADDPVVLVADTQEEDGVAREQVDSADSEICVAHTGGQE----- 1001
Query 1001 TIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVE 1047
+ E + EV + + AD ++
Sbjct 1002 ----MTEPDVVGSQTPIASAEETEVGEACDREGIAEVKATVCADALD 1044
Score = 189 bits (480), Expect = 9e-46, Method: Composition-based stats.
Identities = 68/252 (27%), Positives = 117/252 (46%), Gaps = 18/252 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV D+++ ++V V+VN AN + HG GVAGA+ KA A E+ D +
Sbjct 1318 CITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKAFINETADMVK 1377
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLLS 1150
G +VGG +G L K L++VGP+ E LL+ AY++ N+ + ++ L+S
Sbjct 1378 AQGVCQVGGCYESTGGKLCKKVLNIVGPDARGHGNECYSLLERAYQHINKCDNVVTTLIS 1437
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + V NV L +++ +D + + K + ++A+
Sbjct 1438 AGIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFDVIEKCQVTSVAGTKALSFQLAKNLCR 1497
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+VK F+T + S+ ++ L+E + L ++ L ++ N +
Sbjct 1498 DVK-FVTNACSSLFS--------ESSFVSSYDVLQEVEALRHDIQLDDDARVFVQANMDC 1548
Query 1264 HPDSATLVSDID 1275
P LV+ D
Sbjct 1549 LPTDWRLVNKFD 1560
Score = 50.1 bits (118), Expect = 0.001, Method: Composition-based stats.
Identities = 34/144 (24%), Positives = 58/144 (40%), Gaps = 16/144 (11%)
Query 1663 GLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV 1722
G S NC+L + L+ +Q + L+F +Q + +AG F ++ K++
Sbjct 1109 GFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKLVKSAPKSI 1168
Query 1723 GEL--GDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFK 1780
G V + + S K N C CG + L+G++AV + G +
Sbjct 1169 ILPQGGYVADFAYFFLSQ---CSFKVHANWRCLKCGM-ELKLQGLDAVFFYGDV------ 1218
Query 1781 KGVQIPCTCGKQATKYLVQQESPF 1804
V C CG T L+ + P+
Sbjct 1219 --VSHMCKCGNSMT--LLSADIPY 1238
>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094
Score = 7798 bits (20234), Expect = 0.0, Method: Composition-based stats.
Identities = 2749/5650 (49%), Positives = 3690/5650 (65%), Gaps = 172/5650 (3%)
Query 1531 GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSM 1588
G + + G T +K L + + + TVD +N + V +
Sbjct 1530 GGIDICSQDKVFGYVQQGSFNKATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGE 1585
Query 1589 TYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMS 1648
++G+ G + DG +VTK K +++GK F+ N + ++A D L Y +
Sbjct 1586 SFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYN 1645
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAA 1708
L + KW+ + K A+NNC++ + L LQ + LKF Q+A+ R+G A
Sbjct 1646 MLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPA 1705
Query 1709 NFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAV 1768
F +L+LA G+ D R+ + +F +L + CK CG +Q GV+AV
Sbjct 1706 RFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAV 1764
Query 1769 MYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYT 1828
M+ GTLS E + G + C+CGK+ + V+ + PF++ S PA +L G + A+ +
Sbjct 1765 MHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLICSNTPASVKLPKGVGS-ANIFK 1822
Query 1829 GNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGV 1887
G+ + GHY H+ +++ D + + K ++ G ++D Y +N T TY LD V
Sbjct 1823 GD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDV 1881
Query 1888 VCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNASFDNFKFVCDNIKFADDLNQLTG 1946
E +P L YY Y+T++ I + + NFK + I D LN G
Sbjct 1882 KKIEYNPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGVYTNFKLIGHTI--CDILNAKLG 1939
Query 1947 YKKPA-SRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY 2003
+ E KVT +P GDVV Y +++G KP++W H + N TY
Sbjct 1940 FDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLTY 1999
Query 2004 KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLE 2063
++ + N FDVLK +D +++ D K E+ I L
Sbjct 2000 ----------FNRPLLVDENKFDVLKVDDVDDGGDISESDAK-------ESKEINIIKLS 2042
Query 2064 CNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTL- 2122
K +V +I+ + +K + + D+ ++ ++ N LS + + T+
Sbjct 2043 GVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLTGCRYVVRTANALSMAVNVPTIR 2102
Query 2123 --ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLC 2180
G+ V S+P D + + VV N ++ C N++ + F LL
Sbjct 2103 KFIKFGMTLV-SIPIDLLNLREIKPVFNVVKAVRNKIS-----ACFNFIKWLFVLLFGWI 2156
Query 2181 TFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINII--IWFLLLSV 2238
+ K T +A + + +F K ++ II I+ L +
Sbjct 2157 KISA----DNKVIYTTEVASKLTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNF 2212
Query 2239 CLGSLIYSTAALG--------------VLMSNLGMPSYCTGYREGYLNSTNVTIATYCTG 2284
++I+S L + S + + C Y + YC G
Sbjct 2213 IYANVIFSDFYLPKIGFLPTFVGKIAQWIKSTFSLVTICDLYSIQDVGF----KNQYCNG 2268
Query 2285 SIPCSVCLSGLDSLDTYPSLETIQITISS--FKWDLTAFGLVAEWFLAYILFTRFFYVLG 2342
SI C CL+G D LD Y +++ +Q F +V E ++Y L+T +FY L
Sbjct 2269 SIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF 2328
Query 2343 LAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
+Q+ ++ F+ ++ W + L+++L M P +R YI ASF ++ + HV
Sbjct 2329 ALISIQILTTWLPELFMLSTLHWSVRLLVSLANMLPAHVFMRFYIIIASFIKLFILFRHV 2388
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GC+ C+ CYKRNR+ RV+C+TIV G+ R + V ANGG GFC H WNC++CD++
Sbjct 2389 AYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKP 2448
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G+TFI+ E A DLS + KRPI PTD + + V V + L++++ GQ+TY+ + S
Sbjct 2449 GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFYERDGQRTYDDVNASL 2508
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FV+ NL + KG ++V+V + + ++++ +A+V+Y+Q + +PIL++D+ L++
Sbjct 2509 FVDYSNLLHSKVKGVPNMHVVVVENDA--DKANFLNAAVFYAQSLFRPILMVDKNLITTA 2566
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
V MFD YV+TF S F+V + L L+ATA + + + + VL TF+S AR+
Sbjct 2567 NTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQICKVLDTFLSCARKS 2626
Query 2641 F-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHI 2699
+DSDV+TK + + + + + +E+T +SCNN + TY K +N+ DLG I SA+H+
Sbjct 2627 CSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHV 2686
Query 2700 NAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIA 2759
VAK ++ IW+V F LS + +++ A K L KLT V+V+TT +
Sbjct 2687 QGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFS 2746
Query 2760 LKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRD 2819
LKGG + + ++ ++LV + + P + + K YK +D GV RD
Sbjct 2747 LKGGAVFSYFVYVCFLLSLVCFI---GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRD 2803
Query 2820 IASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILRTT 2877
++ D CFANK FD W+ G Y+N ACP++ AV+ +++G V +P +LR
Sbjct 2804 VSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACPIVVAVVDQDLGSTVFNVPTKVLRY- 2862
Query 2878 NGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTN 2937
LHF+ SA G CYTP I Y++F S CVL++ CT+F A G P PYCY
Sbjct 2863 GYHVLHFITHALSADGVQCYTPHSQISYSNFYASGCVLSSACTMFAMADGSPQPYCYTEG 2922
Query 2938 VLEGSVAYESLRPDTRYVLMDG-SIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGV 2996
+++ + Y SL P RY L + I+FP EG VR+V T YCR G CE ++ G+
Sbjct 2923 LMQNASLYSSLVPHVRYNLANAKGFIRFPEVLREGLVRIVRTRSMSYCRVGLCEEADEGI 2982
Query 2997 CVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIV 3056
C + +G WVLNNDYYRSLPG FCG D +L+ +F L QP+ L ++AS +AG I+A++
Sbjct 2983 CFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVI 3042
Query 3057 VTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYL 3116
V + YY ++ +RAFG+Y+ +V N +++ ++F +L + VY L VY++ Y Y T Y
Sbjct 3043 VVLVFYYLIKLKRAFGDYTSIVFVNVIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYF 3102
Query 3117 TNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE 3176
+++S + H+QW+VM+ ++P W + YI + + H +W F+ RR+ + S TFE
Sbjct 3103 PSEISVIMHLQWLVMYGTIMPLWFCLLYISVVVSNHAFWVFA--YCRRLGTSVRSDGTFE 3160
Query 3177 EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAK 3236
E AL TF++ K+ Y KL++ L +NRYL+LYNKY+Y+SG MDT +YREAAC LAK
Sbjct 3161 EMALTTFMITKDSYCKLKNS--LSDVAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAK 3218
Query 3237 ALNDF-SNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
A++ F +N+GSDVLYQPP S++++ LQSG KM P+ KVE C+V VT G TLNGLWL
Sbjct 3219 AMDTFTNNNGSDVLYQPPTASVSTSFLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWL 3278
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVD 3355
DD VYCPRHVIC++ DM NP+Y +LL R ++ +F V + L V+ + MQ C+L L V
Sbjct 3279 DDKVYCPRHVICSASDMTNPDYTNLLCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVT 3338
Query 3356 TANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNI 3415
N +TPKY F ++PG+TF+VLA YNG P G + MR ++TIKGSFL GSCGSVG+ +
Sbjct 3339 LQNSRTPKYTFGVVKPGETFTVLAAYNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVL 3398
Query 3416 DYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAV 3475
DCV F YMH +EL TG H GTD G+FYGP+ D Q Q D +VN +AWLYAA+
Sbjct 3399 MGDCVKFVYMHQLELSTGCHTGTDFNGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAI 3458
Query 3476 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL 3535
+N WF+ ++ DFN+ A+ + + D V + L++ TG+++ + A++K L
Sbjct 3459 LNNCNWFVQSDKCSVEDFNVWALSNGFSQVKSDLV--IDALASMTGVSLETLLAAIKRL- 3515
Query 3536 QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLV 3595
+NG GR I+GS EDE TP DV +Q +G+ QS R +KG W++ + ++
Sbjct 3516 KNGFQGRQIMGSCSFEDELTPSDVYQQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIIT 3575
Query 3596 QSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN-MVY 3654
+W++F ++ N L + + + AM+ VKHKH +L ++++P L T+ Y N +V
Sbjct 3576 AFVKWTMFMYVTTN-MLSITFCALCVISLAMLLVKHKHLYLTMYIIPVLFTLLYNNYLVV 3634
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL-LILMTARTVYDDGARRVWTLMN 3713
++ + WL S+ + D V+Y +++ ++ +T R++ D + +
Sbjct 3635 YKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGMLLLIGMVFVTLRSINHDLFSFIMFVGR 3693
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+++V Y G+ L++ I + ++ S+ Y+ M A+ ++ V ++F
Sbjct 3694 VISVVSLWYMGSNLEEEILL--MLASLFGTYTWTTALSMAAAK-VIAKWVAVNVLYFTDI 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
++ +++ Y F+GY +CY+GLF L+N FR+ LGVY+Y +S QE RYMN+ GL PPKN
Sbjct 3751 PQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKN 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
S +A LN KLLG+GG P I+V+ QSK++DVKC +VVLL+ LQ L V S+SKLW C
Sbjct 3811 SFEALMLNFKLLGIGGVPIIEVSQFQSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCST 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQAIASE 3947
LHN+IL D AFEK+ LL VL + AVD I ++C++ + LQA+ SE
Sbjct 3871 LHNEILATSDLGVAFEKLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSE 3930
Query 3948 FSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMAD 4006
F ++ S+ + A++ ++A ++G + + LK+L+K+ N+AKS ++RD A+ RKLE+MAD
Sbjct 3931 FVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAYERDRAVARKLERMAD 3990
Query 4007 QAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTT 4066
A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 3991 LALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLA 4050
Query 4067 AAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPL 4126
A L +++PD + Y D TYA +W+IQ + D+D QL+EIS D + WPL
Sbjct 4051 ANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN----WPL 4106
Query 4127 IVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLAL 4184
++ A R N SA LQNNEL P L+ +G QT T YYN + G+ V A+
Sbjct 4107 VIIANRHNEVSATVLQNNELMPAKLKTQVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAI 4164
Query 4185 LSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLG 4244
LSD+ LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V+G
Sbjct 4165 LSDVDGLKYTKILKDDGN-FVVLELDPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVG 4223
Query 4245 SLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGT 4304
++++TVRLQAG ATE +NS++LS CAF+VD K Y D++ GG PI NCVKMLC H GT
Sbjct 4224 TISSTVRLQAGTATEYASNSSILSLCAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGT 4283
Query 4305 GQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFT 4364
G AITV P+A +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV +
Sbjct 4284 GMAITVKPDATTNQDSYGGASVCIYCRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYV 4342
Query 4365 LKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTGTSTDVV 4423
L + VC VCG W+ CSC + +QS D +FLNRV G S ARL PC +G STDV
Sbjct 4343 LTHDVCQVCGFWRDGSCSCVST-DTTVQSKDT-NFLNRVRGTSVDARLVPCASGLSTDVQ 4400
Query 4424 YRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLK 4483
RAFDI N VAG LK NCCRFQ DE+ + +D +FVVKR + Y E Y +K
Sbjct 4401 LRAFDICNASVAGIGLHLKVNCCRFQRVDENGDKLDQFFVVKRTDLTIYNREMECYERVK 4460
Query 4484 DCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNC 4543
DC VA+HDFF F ++G VPHI R+ LTKYTM DL YALRHFD +C L +IL Y
Sbjct 4461 DCKFVAEHDFFTFDVEGSRVPHIVRKDLTKYTMLDLCYALRHFDRNDCMLLCDILSIYAG 4520
Query 4544 CDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQD 4603
C+ YF KKDWYDFVENPDI+ VY LG +AL+ +F D + G+VG+LTLDNQD
Sbjct 4521 CEQSYFTKKDWYDFVENPDIINVYKKLGPIFNRALVSATEFADKLVEVGLVGILTLDNQD 4580
Query 4604 LNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLL 4663
LNG WYDFGD++ PG GV + DSYYS +MP+LT+ AL E +V+ Y +DL+
Sbjct 4581 LNGKWYDFGDYVIAAPGCGVAIADSYYSYMMPMLTMCHALDCELYVNN----AYRLFDLV 4636
Query 4664 KYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVR 4723
+YDFT+ +L+LF++YFK+W YHPN V+C DDRCI+HCANFN+LFS V P T FGPLVR
Sbjct 4637 QYDFTDYKLELFNKYFKHWSMPYHPNTVDCQDDRCIIHCANFNILFSMVLPNTCFGPLVR 4696
Query 4724 KIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDK 4783
+IFVDGVPFVVS GYH++ELG+V N DV+ H RLS K+LL+YAADPA+H AS + L D
Sbjct 4697 QIFVDGVPFVVSIGYHYKELGIVMNMDVDTHRYRLSLKDLLLYAADPALHVASASALYDL 4756
Query 4784 RTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAIS 4843
RT CFSVAA+T+ V FQTVKPGNFN+DFYDF +SKG KEGSSV+LKHFFF QDGNAAI+
Sbjct 4757 RTCCFSVAAITSGVKFQTVKPGNFNQDFYDFILSKGLLKEGSSVDLKHFFFTQDGNAAIT 4816
Query 4844 DYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGK 4903
DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGGCI A+QVIVNN DKSAG+PFNK+GK
Sbjct 4817 DYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGGCIPASQVIVNNYDKSAGYPFNKFGK 4876
Query 4904 ARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQF 4963
ARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI STMT R F
Sbjct 4877 ARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILSTMTGRMF 4936
Query 4964 HQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLR 5023
HQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV+NP LMGWDYPKCDRAMPN+LR
Sbjct 4937 HQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDNPVLMGWDYPKCDRAMPNILR 4996
Query 5024 IMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYAN 5083
I++SLVLARKH CCS S RFYRLANECAQVLSE+VMCGG YVKPGGTSSGDATTA+AN
Sbjct 4997 IVSSLVLARKHEACCSQSDRFYRLANECAQVLSEIVMCGGCYYVKPGGTSSGDATTAFAN 5056
Query 5084 SVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRK 5143
SVFNICQAV+ANV AL+S +GNKI D +R LQ RLY +YR+ VD+ FV E+Y +L K
Sbjct 5057 SVFNICQAVSANVCALMSCNGNKIEDLSIRALQKRLYSHVYRSDMVDSTFVTEYYEFLNK 5116
Query 5144 HFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHE 5203
HFSMMILSDD VVC+NS YAS+G +A+I F+ VLYYQNNVFMSE+KCW E D+ GPHE
Sbjct 5117 HFSMMILSDDGVVCYNSDYASKGYIANISAFQQVLYYQNNVFMSESKCWVENDINNGPHE 5176
Query 5204 FCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTK 5263
FCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFVSLAIDAYPL
Sbjct 5177 FCSQHTMLVKMDGDDVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFVSLAIDAYPLVY 5236
Query 5264 HPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVL 5323
H N+EY VF +YL+YI+KL+++L +LD YSV+L+ + ++ + FY+ MY V+
Sbjct 5237 HENEEYQKVFRVYLEYIKKLYNDLGNQILDSYSVILSTCDGQKFTDESFYKNMYLRSAVM 5296
Query 5324 QAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTD 5383
Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV++T HK VLSV+PYVCNAPGCDV D
Sbjct 5297 QSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHVMATDHKYVLSVSPYVCNAPGCDVND 5356
Query 5384 VTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGD 5443
VT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS + DFN IA+C WT+ D
Sbjct 5357 VTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYIDDFNRIASCKWTDVDD 5416
Query 5444 YILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRN 5503
YILAN CTERLKLFAAET KATEE FK SY AT++E++S+REL LSWE+GK +PPLN+N
Sbjct 5417 YILANECTERLKLFAAETQKATEEAFKQSYASATIQEIVSERELILSWEIGKVKPPLNKN 5476
Query 5504 YVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPT 5563
YVFTGY TKN K +GEY F+K + + V YR TTTYKL+VGD FVLTSH+V LSAPT
Sbjct 5477 YVFTGYHFTKNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFVLTSHSVANLSAPT 5536
Query 5564 LVPQEHYV--RITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLAL 5621
LVPQE+Y R +Y L + F +NV NYQ +GM++Y T+QGPPGTGKSH AIGLA+
Sbjct 5537 LVPQENYSSIRFASVYSVL---ETFQNNVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAV 5593
Query 5622 YYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVF 5681
YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RVEC+DKFK+N T +YVF
Sbjct 5594 YYCTARVVYTAASHAAVDALCEKAYKFLNINDCTRIVPAKVRVECYDKFKINDTTRKYVF 5653
Query 5682 CTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTL 5741
T+NALPE DIVV DE+SM TNY+LSV+NAR+RAKHYVYIGDPAQLPAPR LL+KGTL
Sbjct 5654 TTINALPEMVTDIVVVDEVSMLTNYELSVINARIRAKHYVYIGDPAQLPAPRVLLSKGTL 5713
Query 5742 EPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYK 5801
EP+YFN+V +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA + S+ CFK++YK
Sbjct 5714 EPKYFNTVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYENKLKAKNESSSLCFKVYYK 5773
Query 5802 GVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQ 5861
GV TH+ SSA+N QI ++ +FL NP W KAVFISPYNSQN A ++LGL TQTVDS+Q
Sbjct 5774 GVTTHESSSAVNMQQIYLINKFLKANPLWHKAVFISPYNSQNFAAKRVLGLQTQTVDSAQ 5833
Query 5862 GSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNV 5921
GSEYDYVI++QT ETAHS NVNRFNVAITRAK GILC+MS+ L++ LQFT+L + +
Sbjct 5834 GSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSNMQLFEALQFTTLTLDKVPQ 5893
Query 5922 A-TLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRL 5979
A + + T LFKDCSK +G HP AP+ L+VD K+K T L V + +TY RL
Sbjct 5894 AVETRVQCSTNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRL 5953
Query 5980 ISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTG 6039
IS+MGFK++ ++GY +FIT+EEA++ VRAW+GFD EG HATR+++GTN PLQLGFSTG
Sbjct 5954 ISLMGFKLDVTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTG 6013
Query 6040 VNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTL 6099
++ V TG + F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L
Sbjct 6014 IDFVVEATGLFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHL 6073
Query 6100 KNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFD 6159
+LSD VV V WA FELT ++YF K+G E +C +C +RAT +++ + Y CW HS+ D
Sbjct 6074 IDLSDCVVLVTWAANFELTCLRYFAKVGREISCNVCTKRATAYNSRTGYYGCWRHSVTCD 6133
Query 6160 YVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTI 6219
Y+YNP ++D+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +
Sbjct 6134 YLYNPLIVDIQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNV 6193
Query 6220 EYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQ 6279
EYPII +EL IN +CR +Q +++KAA+L +++ + +DIGNPKAI CV D ++KFYDAQ
Sbjct 6194 EYPIISNELSINTSCRVLQRVMLKAAMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQ 6251
Query 6280 PCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGC 6339
P ++ L YS+ H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC
Sbjct 6252 PI---VKSVKTLLYSFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGC 6308
Query 6340 DGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCI 6399
+GGSLYVNKHAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCI
Sbjct 6309 NGGSLYVNKHAFHTKPFSRAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCI 6368
Query 6400 TRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAF 6459
TRCNLGGAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQSLENV +
Sbjct 6369 TRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTKLQSLENVVY 6428
Query 6460 NVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVP 6519
N+V GH+ GQ GE+P +IIN+ V K+D DV +F N TT P NVA EL+AKR+I+ P
Sbjct 6429 NLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHP 6488
Query 6520 EVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRV 6579
E+K+ NL +D+ VIWDY R++ +T GVC TD+ L V FDGR
Sbjct 6489 ELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------FIDKLNVLFDGRD 6542
Query 6580 DGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI---GEAVKTQFNYYKKVDG 6636
+G ++ F+ + NGV I+ VK L GP +A LNGV + F K+
Sbjct 6543 NGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQD 6602
Query 6637 VVQQLPE-------------------------------TYFTQSRNLQEFKPRSQMEIDF 6665
V+ + T FTQSR + F R+ ME DF
Sbjct 6603 VIFSQFDSLRVSSNQSPQGNLGSNEPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDF 6662
Query 6666 LELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDS 6725
+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S +++F+ DS
Sbjct 6663 IALDQDLFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDS 6722
Query 6726 TVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWC 6785
++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+ + FMLWC
Sbjct 6723 SIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWC 6782
Query 6786 KDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKY 6845
D V TFYP+LQ++ W+PG +MP LYK +E+ L NYG TLP G MMNVAKY
Sbjct 6783 NDEKVMTFYPRLQAASDWKPGYSMPVLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKY 6842
Query 6846 TQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDA 6905
TQLCQYLNT TLAVP NMRV+H GAGS+KGVAPG+AVLRQWLP GT+LVD+DL FVSD+
Sbjct 6843 TQLCQYLNTTTLAVPVNMRVLHLGAGSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDS 6902
Query 6906 DSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSV 6965
+T GDC T+ +WDLIISDMYDP TKN+ + N SK+GFFTYIC I+ KLALGGSV
Sbjct 6903 VATYFGDCITLPFDCQWDLIISDMYDPITKNIGEYNVSKDGFFTYICHMIRDKLALGGSV 6962
Query 6966 AIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHAN 7025
AIKITE SWNA+LYKLMG+FA+WT F TN NASSSE FLIG NYLGKP+ +IDG VMHAN
Sbjct 6963 AIKITEFSWNAELYKLMGYFAFWTVFCTNANASSSEGFLIGINYLGKPKVEIDGNVMHAN 7022
Query 7026 YIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNR 7085
Y+FWRN+ +YSLFDM+KFPLKL GTAV++L+ QINDM+ SLL KG+L++R+ N+
Sbjct 7023 YLFWRNSTVWNGGAYSLFDMAKFPLKLAGTAVINLRADQINDMVYSLLEKGKLLVRDTNK 7082
Query 7086 VVISSDVLVN 7095
V D LVN
Sbjct 7083 EVFVGDSLVN 7092
Score = 654 bits (1688), Expect = 0.0, Method: Composition-based stats.
Identities = 227/1040 (22%), Positives = 379/1040 (36%), Gaps = 183/1040 (18%)
Query 43 RQHLKDGTCGLVEVE----------KGVLPQLEQPYVFIKRSDA---RTAPHGHVMVEL- 88
+ L+ LV +G P +F +RS R A + HV +L
Sbjct 94 QDALQSREAVLVTPPLGMSLEACYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAYQLY 153
Query 89 VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKNGNKGA-------GGHS 135
+ + G+ +G +G+ +G ++P + +PV RK + LRK G KGA GG
Sbjct 154 MIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVPWVMYLRKCGEKGAYNKDHKRGGFE 211
Query 136 YGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
+ + K D D + +P F + L+R G YVD C G
Sbjct 212 HVYNFKVEDAYDLVHDEPKGKFSKK---------AYALIRGYRGVKPLLYVDQYGCDYTG 262
Query 196 ---YPLECIKDLLARAGKASCTL-SEQLDFIDTKRGVYCCREHEHEIAWYTERSEK-SYE 250
LE D + KA + S++L F + +AW+ R +
Sbjct 263 GLADGLEAYADKTLQEMKALFPIWSQELPF-------------DVTVAWHVVRDPRYVMR 309
Query 251 LQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFM---- 297
LQ+ I+ D +G P V+ +SII + + L M
Sbjct 310 LQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYADDSII------LRQHNLVDIMSCFY 363
Query 298 ----GRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCEF-CGTENLT 350
+ + Y V +C + + C D C W G+ + CG T
Sbjct 364 MEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCDFKGWVPGNMIDGFACTTCGHVYET 422
Query 351 KEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGC 409
+ A + G LP N V+ A + G + S Y G + FGGC
Sbjct 423 GDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFTLY------------GQTVVYFGGC 469
Query 410 VFSYVGCHNKCAYWVPRASANI----GCNHTGVVGEGSEGLNDNL-LEILQKEKVNINIV 464
V+ + N W+P +++ G +TGVVG + NL + L + V +
Sbjct 470 VY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGCKAIVKETNLICKALYLDYVQ-HKC 524
Query 465 GDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNI- 523
G+ E + + S L+ +K ++E+ F + + K + +
Sbjct 525 GNLHQRELLGV---------SDVWHKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVC 575
Query 524 --GEQKSILSPLY-----------AFASEAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
G +L L AF A ++ ++ S++ E S+ L AAI L
Sbjct 576 ADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKICHAVVSKSKELLDVSLDSLS-AAIHYL 634
Query 571 DGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDW 630
+ +++D SD T+ +V + T+ L VL
Sbjct 635 NS------KIVDLAQHFSDFGTS-------FVSKIVHFFKTFTTSTALAFAWVLFHVLHG 681
Query 631 LEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCA 690
+ + F+++ I ++ S V + AK + +S++ F +
Sbjct 682 AYIVVESDIYFVKN---IPRYASA-----VAQAFRSVAKVVLDSLRVTFIDGLSCFKIGR 733
Query 691 DSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMP---LKAPKEIIFLEGETL 747
I + G+K+ + G + HS L + L MP KA ++ I+L+G
Sbjct 734 RRICLSGSKIYEVERG---LLHSSQL------PLDVYDLTMPSQVQKAKQKPIYLKGSGS 784
Query 748 PTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMM 807
+ V + T L P E P V +CI + + + Y + +
Sbjct 785 DFSLADSVVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDGHV 839
Query 808 VTNNTFTLKGGAPTKVTFGDDT-VIEVQGY-KSVNITFELDERIDKVLNEKCSAYTVELG 865
+ A +VTF + V E+ K++ + +ELD+ + +LN C + V+
Sbjct 840 GLLDQAWRVPCAGRRVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGVFEVDDT 899
Query 866 TEVNEFACVVADAVIKTLQPVSEL---LTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
++ EF VV DA+ + L P EL + L + + +LFDE+GE LAS +YC
Sbjct 900 VDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGEEVLASKLYC 959
Query 923 SFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQE--EDWL 980
+F P++D D EE E D G A + EE E ED L
Sbjct 960 AFTAPEDD----DFLEESGVEEDDVEGEETD---LTVTSAGEPCVASEQEESSEILEDTL 1012
Query 981 DDDSQQTVGQQDGSEDNQTT 1000
DD ED + +
Sbjct 1013 DDGPCVETSDSQVEEDVEMS 1032
Score = 194 bits (492), Expect = 4e-47, Method: Composition-based stats.
Identities = 59/251 (24%), Positives = 110/251 (44%), Gaps = 17/251 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D +
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + T V L ++ +D + ++ K++ ++++
Sbjct 1392 AGIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFDLISKCQITAVEGTKKLAERLSFNVGR 1451
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+ +K + L++ L ++ L ++ N ++
Sbjct 1452 SIVYETDANKLILSNDVA--------FVSTFNVLQDVLSLRHDIALDDDARTFVQSNVDV 1503
Query 1264 HPDSATLVSDI 1274
P+ +V+
Sbjct 1504 VPEGWRVVNKF 1514
Score = 48.9 bits (115), Expect = 0.003, Method: Composition-based stats.
Identities = 41/196 (21%), Positives = 73/196 (37%), Gaps = 22/196 (11%)
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
++ +V L K NNC+L + L +Q++ +F LQD + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1717 Y--CNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
N V + G V + + L + V C C LKG++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1775 SYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCG 1834
V C CG+ L+ + PF A + LK F Y+
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPFT------AHFALKDKLFCAFITKRSVYKAA 1216
Query 1835 HYKHITSKETLYCIDG 1850
+ ++ +DG
Sbjct 1217 CVVDVNDSHSMAVVDG 1232
>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094
Score = 7797 bits (20231), Expect = 0.0, Method: Composition-based stats.
Identities = 2749/5650 (49%), Positives = 3689/5650 (65%), Gaps = 172/5650 (3%)
Query 1531 GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSM 1588
G + + G T +K L + + + TVD +N + V +
Sbjct 1530 GGIDICSQDKVFGYVQQGSFNKATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGE 1585
Query 1589 TYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMS 1648
+G+ G + DG +VTK K +++GK F+ N + ++A D L Y +
Sbjct 1586 NFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYN 1645
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAA 1708
L + KW+ + K A+NNC++ + L LQ + LKF Q+A+ R+G A
Sbjct 1646 MLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPA 1705
Query 1709 NFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAV 1768
F +L+LA G+ D R+ + +F +L + CK CG +Q GV+AV
Sbjct 1706 RFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAV 1764
Query 1769 MYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYT 1828
M+ GTLS E + G + C+CGK+ + V+ + PF++ S PA +L G + A+ +
Sbjct 1765 MHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLICSNTPASVKLPKGVGS-ANIFK 1822
Query 1829 GNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGV 1887
G+ + GHY H+ +++ D + + K ++ G ++D Y +N T TY LD V
Sbjct 1823 GD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDV 1881
Query 1888 VCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNASFDNFKFVCDNIKFADDLNQLTG 1946
E P L YY Y+T++ I + + NFK + I D LN G
Sbjct 1882 KKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGVYTNFKLIGHTI--CDILNAKLG 1939
Query 1947 YKKPA-SRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY 2003
+ E KVT +P GDVV Y +++G KP++W H + N TY
Sbjct 1940 FDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLTY 1999
Query 2004 KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLE 2063
++ + N FDVLK +D +++ D K E+ I L
Sbjct 2000 ----------FNRPLLVDENKFDVLKVDDVDDGGDISESDAK-------ESKEINIIKLS 2042
Query 2064 CNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTL- 2122
K +V +I+ + +K + + D+ ++ ++ N+LS + + T+
Sbjct 2043 GVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLTGCRYVVRTANDLSMAVNVPTIR 2102
Query 2123 --ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLC 2180
G+ V S+P D + + VV N ++ C N++ + F LL
Sbjct 2103 KFIKFGMTLV-SIPIDLLNLREIKPVFNVVKAVRNKIS-----ACFNFIKWLFVLLFGWI 2156
Query 2181 TFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINII--IWFLLLSV 2238
+ K T +A + + +F K ++ II I+ L +
Sbjct 2157 KISA----DNKVIYTTEVASKLTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNF 2212
Query 2239 CLGSLIYSTAALG--------------VLMSNLGMPSYCTGYREGYLNSTNVTIATYCTG 2284
++I+S L + S + + C Y + YC G
Sbjct 2213 IYANVIFSDFYLPKIGFLPTFVGKIAQWIKSTFSLVTICDLYSIQDVGF----KNQYCNG 2268
Query 2285 SIPCSVCLSGLDSLDTYPSLETIQITISS--FKWDLTAFGLVAEWFLAYILFTRFFYVLG 2342
SI C CL+G D LD Y +++ +Q F +V E ++Y L+T +FY L
Sbjct 2269 SIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF 2328
Query 2343 LAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
+Q+ ++ F+ ++ W + L+++L M P +R YI ASF ++ + HV
Sbjct 2329 ALISIQILTTWLPELFMLSTLHWSVRLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHV 2388
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GC+ C+ CYKRNR+ RV+C+TIV G+ R + V ANGG GFC H WNC++CD++
Sbjct 2389 AYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKP 2448
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G+TFI+ E A DLS + KRPI PTD + + V V + L++++ GQ+TY+ + S
Sbjct 2449 GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFYERDGQRTYDDVNASL 2508
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FV+ NL + KG ++V+V + + ++++ +A+V+Y+Q + +PIL++D+ L++
Sbjct 2509 FVDYSNLLHSKVKGVPNMHVVVVENDA--DKANFLNAAVFYAQSLFRPILMVDKNLITTA 2566
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
V MFD YV+TF S F+V + L L+ATA + + + + VL TF+S AR+
Sbjct 2567 NTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQICKVLDTFLSCARKS 2626
Query 2641 F-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHI 2699
+DSDV+TK + + + + + +E+T +SCNN + TY K +N+ DLG I SA+H+
Sbjct 2627 CSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHV 2686
Query 2700 NAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIA 2759
VAK ++ IW+V F LS + +++ A K L KLT V+V+TT +
Sbjct 2687 QGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFS 2746
Query 2760 LKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRD 2819
LKGG + + ++ ++LV + + P + + K YK +D GV RD
Sbjct 2747 LKGGAVFSYFVYVCFLLSLVCFI---GLWCLMPTYTVHKSDFQLPVYTSYKVLDNGVIRD 2803
Query 2820 IASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILRTT 2877
++ D CFANK FD W+ G Y+N ACP++ AV+ +++G V +P +LR
Sbjct 2804 VSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACPIVVAVVDQDLGSTVFNVPTKVLRY- 2862
Query 2878 NGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTN 2937
LHF+ SA G CYTP I Y++F S CVL++ CT+F A G P PYCY
Sbjct 2863 GYHVLHFITHALSADGVQCYTPHSQISYSNFYASGCVLSSACTMFAMADGSPQPYCYTEG 2922
Query 2938 VLEGSVAYESLRPDTRYVLMDG-SIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGV 2996
+++ + Y SL P RY L + I+FP EG VR+V T YCR G CE ++ G+
Sbjct 2923 LMQNASLYSSLVPHVRYNLANAKGFIRFPEVLREGLVRIVRTRSMSYCRVGLCEEADEGI 2982
Query 2997 CVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIV 3056
C + +G WVLNNDYYRSLPG FCG D +L+ +F L QP+ L ++AS +AG I+A++
Sbjct 2983 CFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVI 3042
Query 3057 VTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYL 3116
V + YY ++ +RAFG+Y+ +V N +++ ++F +L + VY L VY++ Y Y T Y
Sbjct 3043 VVLVFYYLIKLKRAFGDYTSIVFVNVIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYF 3102
Query 3117 TNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE 3176
+++S + H+QW+VM+ ++P W + YI + + H +W F+ RR+ + S TFE
Sbjct 3103 PSEISVIMHLQWLVMYGTIMPLWFCLLYISVVVSNHAFWVFA--YCRRLGTSVRSDGTFE 3160
Query 3177 EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAK 3236
E AL TF++ K+ Y KL++ L +NRYL+LYNKY+Y+SG MDT +YREAAC LAK
Sbjct 3161 EMALTTFMITKDSYCKLKNS--LSDVAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAK 3218
Query 3237 ALNDF-SNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
A++ F +N+GSDVLYQPP S++++ LQSG KM P+ KVE C+V VT G TLNGLWL
Sbjct 3219 AMDTFTNNNGSDVLYQPPTASVSTSFLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWL 3278
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVD 3355
DD VYCPRHVIC++ DM NP+Y +LL R ++ +F V + L V+ + MQ C+L L V
Sbjct 3279 DDKVYCPRHVICSASDMTNPDYTNLLCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVT 3338
Query 3356 TANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNI 3415
N +TPKY F ++PG+TF+VLA YNG P G + MR ++TIKGSFL GSCGSVG+ +
Sbjct 3339 LQNSRTPKYTFGVVKPGETFTVLAAYNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVL 3398
Query 3416 DYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAV 3475
DCV F YMH +EL TG H GTD G+FYGP+ D Q Q D +VN +AWLYAA+
Sbjct 3399 MGDCVKFVYMHQLELSTGCHTGTDFNGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAI 3458
Query 3476 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL 3535
+N WF+ ++ DFN+ A+ + + D V + L++ TG+++ + A++K L
Sbjct 3459 LNNCNWFVQSDKCSVEDFNVWALSNGFSQVKSDLV--IDALASMTGVSLETLLAAIKRL- 3515
Query 3536 QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLV 3595
+NG GR I+GS EDE TP DV +Q +G+ QS R +KG W++ + ++
Sbjct 3516 KNGFQGRQIMGSCSFEDELTPSDVYQQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIIT 3575
Query 3596 QSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN-MVY 3654
+W++F ++ N L + + + AM+ VKHKH +L ++++P L T+ Y N +V
Sbjct 3576 AFVKWTMFMYVTTN-MLSITFCALCVISLAMLLVKHKHLYLTMYIIPVLFTLLYNNYLVV 3634
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL-LILMTARTVYDDGARRVWTLMN 3713
++ + WL S+ + D V+Y +++ ++ +T R++ D + +
Sbjct 3635 YKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGMLLLIGMVFVTLRSINHDLFSFIMFVGR 3693
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+++V Y G+ L++ I + ++ S+ Y+ M A+ ++ V ++F
Sbjct 3694 VISVVSLWYMGSNLEEEILL--MLASLFGTYTWTTALSMAAAK-VIAKWVAVNVLYFTDI 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
++ +++ Y F+GY +CY+GLF L+N FR+ LGVY+Y +S QE RYMN+ GL PPKN
Sbjct 3751 PQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKN 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
S +A LN KLLG+GG P I+V+ QSK++DVKC +VVLL+ LQ L V S+SKLW C
Sbjct 3811 SFEALMLNFKLLGIGGVPIIEVSQFQSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCST 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQAIASE 3947
LHN+IL D AFEK+ LL VL + AVD I ++C++ + LQA+ SE
Sbjct 3871 LHNEILATSDLGVAFEKLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSE 3930
Query 3948 FSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMAD 4006
F ++ S+ + A++ ++A ++G + + LK+L+K+ N+AKS ++RD A+ RKLE+MAD
Sbjct 3931 FVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAYERDRAVARKLERMAD 3990
Query 4007 QAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTT 4066
A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 3991 LALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLA 4050
Query 4067 AAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPL 4126
A L +++PD + Y D TYA +W+IQ + D+D QL+EIS D + WPL
Sbjct 4051 ANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN----WPL 4106
Query 4127 IVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLAL 4184
++ A R N SA LQNNEL P L+ +G QT T YYN + G+ V A+
Sbjct 4107 VIIANRHNEVSATVLQNNELMPAKLKTQVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAI 4164
Query 4185 LSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLG 4244
LSD+ LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V+G
Sbjct 4165 LSDVDGLKYTKILKDDGN-FVVLELDPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVG 4223
Query 4245 SLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGT 4304
++++TVRLQAG ATE +NS++LS CAF+VD K Y D++ GG PI NCVKMLC H GT
Sbjct 4224 TISSTVRLQAGTATEYASNSSILSLCAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGT 4283
Query 4305 GQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFT 4364
G AITV P+A +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV +
Sbjct 4284 GMAITVKPDATTNQDSYGGASVCIYCRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYV 4342
Query 4365 LKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTGTSTDVV 4423
L + VC VCG W+ CSC + +QS D +FLNRV G S ARL PC +G STDV
Sbjct 4343 LTHDVCQVCGFWRDGSCSCVST-DTTVQSKDT-NFLNRVRGTSVDARLVPCASGLSTDVQ 4400
Query 4424 YRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLK 4483
RAFDI N VAG LK NCCRFQ DE+ + +D +FVVKR + Y E Y +K
Sbjct 4401 LRAFDICNASVAGIGLHLKVNCCRFQRVDENGDKLDQFFVVKRTDLTIYNREMECYERVK 4460
Query 4484 DCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNC 4543
DC VA+HDFF F ++G VPHI R+ LTKYTM DL YALRHFD +C L +IL Y
Sbjct 4461 DCKFVAEHDFFTFDVEGSRVPHIVRKDLTKYTMLDLCYALRHFDRNDCMLLCDILSIYAG 4520
Query 4544 CDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQD 4603
C+ YF KKDWYDFVENPDI+ VY LG +AL+ +F D + G+VG+LTLDNQD
Sbjct 4521 CEQSYFTKKDWYDFVENPDIINVYKKLGPIFNRALVSATEFADKLVEVGLVGILTLDNQD 4580
Query 4604 LNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLL 4663
LNG WYDFGD++ PG GV + DSYYS +MP+LT+ AL E +V+ Y +DL+
Sbjct 4581 LNGKWYDFGDYVIAAPGCGVAIADSYYSYMMPMLTMCHALDCELYVNN----AYRLFDLV 4636
Query 4664 KYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVR 4723
+YDFT+ +L+LF++YFK+W YHPN V+C DDRCI+HCANFN+LFS V P T FGPLVR
Sbjct 4637 QYDFTDYKLELFNKYFKHWSMPYHPNTVDCQDDRCIIHCANFNILFSMVLPNTCFGPLVR 4696
Query 4724 KIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDK 4783
+IFVDGVPFVVS GYH++ELG+V N DV+ H RLS K+LL+YAADPA+H AS + L D
Sbjct 4697 QIFVDGVPFVVSIGYHYKELGIVMNMDVDTHRYRLSLKDLLLYAADPALHVASASALYDL 4756
Query 4784 RTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAIS 4843
RT CFSVAA+T+ V FQTVKPGNFN+DFYDF +SKG KEGSSV+LKHFFF QDGNAAI+
Sbjct 4757 RTCCFSVAAITSGVKFQTVKPGNFNQDFYDFILSKGLLKEGSSVDLKHFFFTQDGNAAIT 4816
Query 4844 DYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGK 4903
DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGGCI A+QVIVNN DKSAG+PFNK+GK
Sbjct 4817 DYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGGCIPASQVIVNNYDKSAGYPFNKFGK 4876
Query 4904 ARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQF 4963
ARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI STMT R F
Sbjct 4877 ARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILSTMTGRMF 4936
Query 4964 HQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLR 5023
HQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV+NP LMGWDYPKCDRAMPN+LR
Sbjct 4937 HQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDNPVLMGWDYPKCDRAMPNILR 4996
Query 5024 IMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYAN 5083
I++SLVLARKH CCS S RFYRLANECAQVLSE+VMCGG YVKPGGTSSGDATTA+AN
Sbjct 4997 IVSSLVLARKHEACCSQSDRFYRLANECAQVLSEIVMCGGCYYVKPGGTSSGDATTAFAN 5056
Query 5084 SVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRK 5143
SVFNICQAV+ANV AL+S +GNKI D +R LQ RLY +YR+ VD+ FV E+Y +L K
Sbjct 5057 SVFNICQAVSANVCALMSCNGNKIEDLSIRALQKRLYSHVYRSDMVDSTFVTEYYEFLNK 5116
Query 5144 HFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHE 5203
HFSMMILSDD VVC+NS YAS+G +A+I F+ VLYYQNNVFMSE+KCW E D+ GPHE
Sbjct 5117 HFSMMILSDDGVVCYNSDYASKGYIANISAFQQVLYYQNNVFMSESKCWVENDINNGPHE 5176
Query 5204 FCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTK 5263
FCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFVSLAIDAYPL
Sbjct 5177 FCSQHTMLVKMDGDDVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFVSLAIDAYPLVY 5236
Query 5264 HPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVL 5323
H N+EY VF +YL+YI+KL+++L +LD YSV+L+ + ++ + FY+ MY V+
Sbjct 5237 HENEEYQKVFRVYLEYIKKLYNDLGNQILDSYSVILSTCDGQKFTDESFYKNMYLRSAVM 5296
Query 5324 QAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTD 5383
Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV++T HK VLSV+PYVCNAPGCDV D
Sbjct 5297 QSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHVMATDHKYVLSVSPYVCNAPGCDVND 5356
Query 5384 VTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGD 5443
VT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS + DFN IA+C WT+ D
Sbjct 5357 VTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYIDDFNRIASCKWTDVDD 5416
Query 5444 YILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRN 5503
YILAN CTERLKLFAAET KATEE FK SY AT++E++S+REL LSWE+GK +PPLN+N
Sbjct 5417 YILANECTERLKLFAAETQKATEEAFKQSYASATIQEIVSERELILSWEIGKVKPPLNKN 5476
Query 5504 YVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPT 5563
YVFTGY TKN K +GEY F+K + + V YR TTTYKL+VGD FVLTSH+V LSAPT
Sbjct 5477 YVFTGYHFTKNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFVLTSHSVANLSAPT 5536
Query 5564 LVPQEHYV--RITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLAL 5621
LVPQE+Y R +Y L + F +NV NYQ +GM++Y T+QGPPGTGKSH AIGLA+
Sbjct 5537 LVPQENYSSIRFASVYSVL---ETFQNNVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAV 5593
Query 5622 YYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVF 5681
YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RVEC+DKFK+N T +YVF
Sbjct 5594 YYCTARVVYTAASHAAVDALCEKAYKFLNINDCTRIVPAKVRVECYDKFKINDTTRKYVF 5653
Query 5682 CTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTL 5741
T+NALPE DIVV DE+SM TNY+LSV+NAR+RAKHYVYIGDPAQLPAPR LL+KGTL
Sbjct 5654 TTINALPEMVTDIVVVDEVSMLTNYELSVINARIRAKHYVYIGDPAQLPAPRVLLSKGTL 5713
Query 5742 EPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYK 5801
EP+YFN+V +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA + S+ CFK++YK
Sbjct 5714 EPKYFNTVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYENKLKAKNESSSLCFKVYYK 5773
Query 5802 GVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQ 5861
GV TH+ SSA+N QI ++ +FL NP W KAVFISPYNSQN A ++LGL TQTVDS+Q
Sbjct 5774 GVTTHESSSAVNMQQIYLINKFLKANPLWHKAVFISPYNSQNFAAKRVLGLQTQTVDSAQ 5833
Query 5862 GSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNV 5921
GSEYDYVI++QT ETAHS NVNRFNVAITRAK GILC+MS+ L++ LQFT+L + +
Sbjct 5834 GSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSNMQLFEALQFTTLTLDKVPQ 5893
Query 5922 A-TLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRL 5979
A + + T LFKDCSK +G HP AP+ L+VD K+K T L V + +TY RL
Sbjct 5894 AVETRVQCSTNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRL 5953
Query 5980 ISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTG 6039
IS+MGFK++ ++GY +FIT+EEA++ VRAW+GFD EG HATR+++GTN PLQLGFSTG
Sbjct 5954 ISLMGFKLDVTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTG 6013
Query 6040 VNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTL 6099
++ V TG + F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L
Sbjct 6014 IDFVVEATGLFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHL 6073
Query 6100 KNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFD 6159
+LSD VV V WA FELT ++YF K+G E +C +C +RAT +++ + Y CW HS+ D
Sbjct 6074 IDLSDCVVLVTWAANFELTCLRYFAKVGREISCNVCTKRATAYNSRTGYYGCWRHSVTCD 6133
Query 6160 YVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTI 6219
Y+YNP ++D+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +
Sbjct 6134 YLYNPLIVDIQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNV 6193
Query 6220 EYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQ 6279
EYPII +EL IN +CR +Q +++KAA+L +++ + +DIGNPKAI CV D ++KFYDAQ
Sbjct 6194 EYPIISNELSINTSCRVLQRVMLKAAMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQ 6251
Query 6280 PCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGC 6339
P ++ L YS+ H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC
Sbjct 6252 PI---VKSVKTLLYSFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGC 6308
Query 6340 DGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCI 6399
+GGSLYVNKHAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCI
Sbjct 6309 NGGSLYVNKHAFHTKPFSRAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCI 6368
Query 6400 TRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAF 6459
TRCNLGGAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQSLENV +
Sbjct 6369 TRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTKLQSLENVVY 6428
Query 6460 NVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVP 6519
N+V GH+ GQ GE+P +IIN+ V K+D DV +F N TT P NVA EL+AKR+I+ P
Sbjct 6429 NLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHP 6488
Query 6520 EVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRV 6579
E+K+ NL +D+ VIWDY R++ +T GVC TD+ L V FDGR
Sbjct 6489 ELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------FIDKLNVLFDGRD 6542
Query 6580 DGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI---GEAVKTQFNYYKKVDG 6636
+G ++ F+ + NGV I+ VK L GP +A LNGV + F K+
Sbjct 6543 NGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQD 6602
Query 6637 VVQQLPE-------------------------------TYFTQSRNLQEFKPRSQMEIDF 6665
V+ + T FTQSR + F R+ ME DF
Sbjct 6603 VIFSQFDSLRVSSNQSPQGNLGSNEPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDF 6662
Query 6666 LELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDS 6725
+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S +++F+ DS
Sbjct 6663 IALDQDLFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDS 6722
Query 6726 TVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWC 6785
++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+ + FMLWC
Sbjct 6723 SIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWC 6782
Query 6786 KDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKY 6845
D V TFYP+LQ++ W+PG +MP LYK +E+ L NYG TLP G MMNVAKY
Sbjct 6783 NDEKVMTFYPRLQAASDWKPGYSMPVLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKY 6842
Query 6846 TQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDA 6905
TQLCQYLNT TLAVP NMRV+H GAGS+KGVAPG+AVLRQWLP GT+LVD+DL FVSD+
Sbjct 6843 TQLCQYLNTTTLAVPVNMRVLHLGAGSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDS 6902
Query 6906 DSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSV 6965
+T GDC T+ +WDLIISDMYDP TKN+ + N SK+GFFTYIC I+ KLALGGSV
Sbjct 6903 VATYFGDCITLPFDCQWDLIISDMYDPITKNIGEYNVSKDGFFTYICHMIRDKLALGGSV 6962
Query 6966 AIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHAN 7025
AIKITE SWNA+LYKLMG+FA+WT F TN NASSSE FLIG NYLGKP+ +IDG VMHAN
Sbjct 6963 AIKITEFSWNAELYKLMGYFAFWTVFCTNANASSSEGFLIGINYLGKPKVEIDGNVMHAN 7022
Query 7026 YIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNR 7085
Y+FWRN+ +YSLFDM+KFPLKL GTAV++L+ QINDM+ SLL KG+L++R+ N+
Sbjct 7023 YLFWRNSTVWNGGAYSLFDMAKFPLKLAGTAVINLRADQINDMVYSLLEKGKLLVRDTNK 7082
Query 7086 VVISSDVLVN 7095
V D LVN
Sbjct 7083 EVFVGDSLVN 7092
Score = 654 bits (1686), Expect = 0.0, Method: Composition-based stats.
Identities = 227/1040 (22%), Positives = 379/1040 (36%), Gaps = 183/1040 (18%)
Query 43 RQHLKDGTCGLVEVE----------KGVLPQLEQPYVFIKRSDA---RTAPHGHVMVEL- 88
+ L+ LV +G P +F +RS R A + HV +L
Sbjct 94 QDALQSREAVLVTPPLGMSLEACYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAYQLY 153
Query 89 VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKNGNKGA-------GGHS 135
+ + G+ +G +G+ +G ++P + +PV RK + LRK G KGA GG
Sbjct 154 MIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVPWVMYLRKCGEKGAYNKDHKRGGFE 211
Query 136 YGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
+ + K D D + +P F + L+R G YVD C G
Sbjct 212 HVYNFKVEDAYDLVHDEPKGKFSKK---------AYALIRGYRGVKPLLYVDQYGCDYTG 262
Query 196 ---YPLECIKDLLARAGKASCTL-SEQLDFIDTKRGVYCCREHEHEIAWYTERSEK-SYE 250
LE D + KA + S++L F + +AW+ R +
Sbjct 263 GLADGLEAYADKTLQEMKALFPIWSQELPF-------------DVTVAWHVVRDPRYVMR 309
Query 251 LQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFM---- 297
LQ+ I+ D +G P V+ +SII + + L M
Sbjct 310 LQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYADDSII------LRQHNLVDIMSCFY 363
Query 298 ----GRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCEF-CGTENLT 350
+ + Y V +C + + C D C W G+ + CG T
Sbjct 364 MEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCDFKGWVPGNMIDGFACTTCGHVYET 422
Query 351 KEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGC 409
+ A + G LP N V+ A + G + S Y G + FGGC
Sbjct 423 GDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFTLY------------GQTVVYFGGC 469
Query 410 VFSYVGCHNKCAYWVPRASANI----GCNHTGVVGEGSEGLNDNL-LEILQKEKVNINIV 464
V+ + N W+P +++ G +TGVVG + NL + L + V +
Sbjct 470 VY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGCKAIVKETNLICKALYLDYVQ-HKC 524
Query 465 GDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNI- 523
G+ E + + S L+ +K ++E+ F + + K + +
Sbjct 525 GNLHQRELLGV---------SDVWHKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVC 575
Query 524 --GEQKSILSPLY-----------AFASEAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
G +L L AF A ++ ++ S++ E S+ L AAI L
Sbjct 576 ADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKICHAVVSKSKELLDVSLDSLS-AAIHYL 634
Query 571 DGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDW 630
+ +++D SD T+ +V + T+ L VL
Sbjct 635 NS------KIVDLAQHFSDFGTS-------FVSKIVHFFKTFTTSTALAFAWVLFHVLHG 681
Query 631 LEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCA 690
+ + F+++ I ++ S V + AK + +S++ F +
Sbjct 682 AYIVVESDIYFVKN---IPRYASA-----VAQAFRSVAKVVLDSLRVTFIDGLSCFKIGR 733
Query 691 DSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMP---LKAPKEIIFLEGETL 747
I + G+K+ + G + HS L + L MP KA ++ I+L+G
Sbjct 734 RRICLSGSKIYEVERG---LLHSSQL------PLDVYDLTMPSQVQKAKQKPIYLKGSGS 784
Query 748 PTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMM 807
+ V + T L P E P V +CI + + + Y + +
Sbjct 785 DFSLADSVVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDGHV 839
Query 808 VTNNTFTLKGGAPTKVTFGDDT-VIEVQGY-KSVNITFELDERIDKVLNEKCSAYTVELG 865
+ A +VTF + V E+ K++ + +ELD+ + +LN C + V+
Sbjct 840 GLLDQAWRVPCAGRRVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGVFEVDDT 899
Query 866 TEVNEFACVVADAVIKTLQPVSEL---LTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
++ EF VV DA+ + L P EL + L + + +LFDE+GE LAS +YC
Sbjct 900 VDMEEFYAVVVDAIEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGEEVLASKLYC 959
Query 923 SFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQE--EDWL 980
+F P++D D EE E D G A + EE E ED L
Sbjct 960 AFTAPEDD----DFLEESGVEEDDVEGEETD---LTVTSAGEPCVASEQEESSEILEDTL 1012
Query 981 DDDSQQTVGQQDGSEDNQTT 1000
DD ED + +
Sbjct 1013 DDGPCVETSDSQVEEDVEMS 1032
Score = 194 bits (492), Expect = 4e-47, Method: Composition-based stats.
Identities = 59/251 (24%), Positives = 110/251 (44%), Gaps = 17/251 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D +
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + T V L ++ +D + ++ K++ ++++
Sbjct 1392 AGIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFDLISKCQITAVEGTKKLAERLSFNVGR 1451
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+ +K + L++ L ++ L ++ N ++
Sbjct 1452 SIVYETDANKLILSNDVA--------FVSTFNVLQDVLSLRHDIALDDDARTFVQSNVDV 1503
Query 1264 HPDSATLVSDI 1274
P+ +V+
Sbjct 1504 VPEGWRVVNKF 1514
Score = 48.9 bits (115), Expect = 0.003, Method: Composition-based stats.
Identities = 41/196 (21%), Positives = 73/196 (37%), Gaps = 22/196 (11%)
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
++ +V L K NNC+L + L +Q++ +F LQD + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1717 Y--CNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
N V + G V + + L + V C C LKG++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1775 SYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCG 1834
V C CG+ L+ + PF A + LK F Y+
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPFT------AHFALKDKLFCAFITKRSVYKAA 1216
Query 1835 HYKHITSKETLYCIDG 1850
+ ++ +DG
Sbjct 1217 CVVDVNDSHSMAVVDG 1232
>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094
Score = 7745 bits (20095), Expect = 0.0, Method: Composition-based stats.
Identities = 2739/5650 (48%), Positives = 3675/5650 (65%), Gaps = 172/5650 (3%)
Query 1531 GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSM 1588
G + + G T +K L + + + TVD +N + V +
Sbjct 1530 GGIDICSQDKVFGYVQQGSFNKATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGE 1585
Query 1589 TYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMS 1648
++G+ G + DG +VTK K +++GK F+ N + ++A D L Y +
Sbjct 1586 SFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYN 1645
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAA 1708
L + KW+ + K A+NNC++ + L LQ + LKF Q+A+ R+G A
Sbjct 1646 MLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPA 1705
Query 1709 NFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAV 1768
F +L+LA G+ D R+ + +F +L + CK CG +Q GV+AV
Sbjct 1706 RFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAV 1764
Query 1769 MYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYT 1828
M+ GTLS E + G + C+CGK+ + V+ + PF++ S PA +L G + A+ +
Sbjct 1765 MHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLICSNTPASVKLPKGVGS-ANIFK 1822
Query 1829 GNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGV 1887
G+ + GHY H+ +++ D + + K ++ G ++D Y +N T TY LD V
Sbjct 1823 GD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDV 1881
Query 1888 VCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNASFDNFKFVCDNIKFADDLNQLTG 1946
E P L YY Y+T++ I + + NFK + + D LN G
Sbjct 1882 KKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGVYTNFKLIGHTV--CDILNAKLG 1939
Query 1947 YKKPA-SRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY 2003
+ E KVT +P GDVV Y +++G KP++W H + N TY
Sbjct 1940 FDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLTY 1999
Query 2004 KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLE 2063
++ + N FDVLK +D +++ D K E I L
Sbjct 2000 ----------FNRPLLVDENKFDVLKVDDVDDGGDISESDAK-------EPKEINIIKLS 2042
Query 2064 CNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTL- 2122
K +V +I+ + +K + + D+ ++ ++ N LSR + + T+
Sbjct 2043 GVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLTGCRCVVRTANALSRAVNVPTIR 2102
Query 2123 --ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLC 2180
G+ V S+P D + + VV N ++ C N++ + F LL
Sbjct 2103 KFIKFGMTLV-SIPIDLLNLREIKPVFNVVKAVRNKIS-----ACFNFIKWLFVLLFGWI 2156
Query 2181 TFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINII--IWFLLLSV 2238
+ K T +A + + +F K ++ II I+ L +
Sbjct 2157 KISA----DNKVIYTTEVASKLTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNF 2212
Query 2239 CLGSLIYSTAALG--------------VLMSNLGMPSYCTGYREGYLNSTNVTIATYCTG 2284
++I+S L + + + + C Y + YC G
Sbjct 2213 IYANVIFSDFYLPKIGFLPTFVGKIAQWIKNTFSLVTICDLYSIQDVGF----KNQYCNG 2268
Query 2285 SIPCSVCLSGLDSLDTYPSLETIQITISS--FKWDLTAFGLVAEWFLAYILFTRFFYVLG 2342
SI C CL+G D LD Y +++ +Q F +V E ++Y L+T +FY L
Sbjct 2269 SIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF 2328
Query 2343 LAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
+Q+ ++ F+ ++ W + L+++L M P +R YI ASF ++ + HV
Sbjct 2329 ALISIQILTTWLPELFMLSTLHWSVRLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHV 2388
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GC+ S C+ CYKRNR+ RV+C+TIV G+ R + ANGG GFC H WNC++CD++
Sbjct 2389 AYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRYYDAMANGGTGFCSKHQWNCIDCDSYKP 2448
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G+TFI+ E A DLS + KRPI PTD + + V V + L++D+ GQ+TY+ + S
Sbjct 2449 GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFYDRDGQRTYDDVNASL 2508
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FV+ NL + K ++V+V + + ++++ +A+V+Y+Q + +PIL++D+ L++
Sbjct 2509 FVDYSNLLHSKVKSVPNMHVVVVENDA--DKANFLNAAVFYAQSLFRPILMVDKNLITTA 2566
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
V MFD YV+TF S F+V + L L+ATA + + + + VL TF+S AR+
Sbjct 2567 NTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQICKVLDTFLSCARKS 2626
Query 2641 F-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHI 2699
+DSDV+TK + + + + + +E+T +SCNN + TY K +N+ DLG I SA+H+
Sbjct 2627 CSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHV 2686
Query 2700 NAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIA 2759
VAK ++ IW+V F LS + +++ A K L KLT V+V+TT +
Sbjct 2687 QGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFS 2746
Query 2760 LKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRD 2819
LKGG + + ++ ++LV + + P + + K YK +D GV RD
Sbjct 2747 LKGGAVFSYFVYVCFVLSLVCFI---GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRD 2803
Query 2820 IASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILRTT 2877
++ D CFANK FD W+ G Y+N ACP++ AV+ ++ G V +P +LR
Sbjct 2804 VSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACPIVVAVVDQDFGSTVFNVPTKVLRY- 2862
Query 2878 NGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTN 2937
LHF+ SA G CYTP I Y++F S CVL++ CT+F A G P PYCY
Sbjct 2863 GYHVLHFITHALSADGVQCYTPHSQISYSNFYASGCVLSSACTMFAMADGSPQPYCYTDG 2922
Query 2938 VLEGSVAYESLRPDTRYVLMDG-SIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGV 2996
+++ + Y SL P RY L + I+FP EG VR+V T YCR G CE ++ G+
Sbjct 2923 LMQNASLYSSLVPHVRYNLANAKGFIRFPEVLREGLVRIVRTRSMPYCRVGLCEEADEGI 2982
Query 2997 CVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIV 3056
C + +G WVLNNDYYRSLPG FCG D +L+ +F L QP+ L ++AS +AG I+A++
Sbjct 2983 CFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVI 3042
Query 3057 VTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYL 3116
V + YY ++ +RAFG+Y+ +V N +++ ++F +L + VY L VY++ Y Y T Y
Sbjct 3043 VVLVFYYLIKLKRAFGDYTSIVFVNVIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYF 3102
Query 3117 TNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE 3176
+++S + H+QW+VM+ ++P W + YI + + H +W FS R++ + S TFE
Sbjct 3103 PSEISVIMHLQWLVMYGTIMPLWFCLLYISVVVSNHAFWVFS--YCRQLGTSVRSDGTFE 3160
Query 3177 EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAK 3236
E AL TF++ K+ Y KL++ L +NRYL+LYNKY+Y+SG MDT +YREAAC LAK
Sbjct 3161 EMALTTFMITKDSYCKLKNS--LSDVAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAK 3218
Query 3237 ALNDF-SNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
A++ F +N+GSDVLYQPP S++++ LQSG KM P+ KVE C+V VT G TLNGLWL
Sbjct 3219 AMDTFTNNNGSDVLYQPPTASVSTSFLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWL 3278
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVD 3355
D VYCPRHVIC++ DM NP+Y +LL R ++ +F V + L V+ + MQ C+L L V
Sbjct 3279 GDKVYCPRHVICSASDMTNPDYTNLLCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVT 3338
Query 3356 TANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNI 3415
N +TPKY F ++PG+TF+VLA YNG P G + MR ++TIKGSFL GSCGSV + I
Sbjct 3339 LQNSRTPKYTFGVVKPGETFTVLAAYNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVVYVI 3398
Query 3416 DYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAV 3475
DCV F YMH +EL TG H GTD G+FYGP+ D Q Q D +VN +AWLYAA+
Sbjct 3399 MGDCVKFVYMHQLELSTGCHTGTDFNGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAI 3458
Query 3476 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL 3535
+N WF+ ++ DFN+ A+ + + D V + L++ TG+++ + A++K L
Sbjct 3459 LNNCNWFVQSDKCSVEDFNVWALSNGFSQVKSDLV--IDALASMTGVSLETLLAAIKHL- 3515
Query 3536 QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLV 3595
+NG GR I+GS EDE TP DV +Q +G+ QS R +KG W++ + ++
Sbjct 3516 KNGFQGRQIMGSCSFEDELTPSDVYQQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIIT 3575
Query 3596 QSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN-MVY 3654
+W++F ++ N L + + + M+ VKHKH +L ++++P L T+ Y N +V
Sbjct 3576 AFVKWTMFMYVTTN-MLSITFCALCVISLTMLLVKHKHLYLTMYIIPVLFTLLYNNYLVV 3634
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL-LILMTARTVYDDGARRVWTLMN 3713
++ + WL S+ + D V+Y +++ ++ +T R++ + +
Sbjct 3635 YKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGMLLLIGMVFVTLRSINQYLFSFIMFVGR 3693
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+++V Y G+ L++ I + ++ S+ Y+ M A+ ++ V ++F
Sbjct 3694 VISVVSLWYMGSNLEEEILL--MLASLFGTYTWTTALSMAAAK-VIAKWVAVNVLYFTDI 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
++ +++ Y F+GY +CY+GLF L+N FR+ LGVY+Y +S QE RYMN+ GL PPKN
Sbjct 3751 PQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKN 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
S +A LN KLLG+GG P I+V+ QSK++DVKC +VVLL+ LQ L V S+SKLW C
Sbjct 3811 SFEALMLNFKLLGIGGVPIIEVSQFQSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCST 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQAIASE 3947
LHN+IL D AFEK+ LL VL + AVD I ++C++ + LQA+ SE
Sbjct 3871 LHNEILATSDLGVAFEKLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSE 3930
Query 3948 FSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMAD 4006
F ++ S+ + A++ ++A ++G + + LK+L+K+ N+AKS ++RD A+ RKLE+MAD
Sbjct 3931 FVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAYERDRAVARKLERMAD 3990
Query 4007 QAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTT 4066
A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 3991 LALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLA 4050
Query 4067 AAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPL 4126
A L +++PD + Y D TYA +W+IQ + D+D QL EIS D + WPL
Sbjct 4051 ANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLHEISDDCN----WPL 4106
Query 4127 IVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLAL 4184
++ A R N SA LQNNEL P L+ +G QT T YYN + G+ V A+
Sbjct 4107 VIIANRHNEVSATALQNNELMPAKLKTQVVNSGPDQTCNTPTQ--CYYNNSYNGKIVYAI 4164
Query 4185 LSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLG 4244
LSD+ LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V+G
Sbjct 4165 LSDVDGLKYTKILKDDGN-FVVLELDPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVG 4223
Query 4245 SLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGT 4304
++++TVRLQAG ATE +NS++LS CAF+VD K Y D++ GG PI NCVKMLC H GT
Sbjct 4224 TISSTVRLQAGTATEYASNSSILSLCAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGT 4283
Query 4305 GQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFT 4364
G AITV P+A Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV +
Sbjct 4284 GMAITVKPDATTSQDSYGGASVCIYCRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYV 4342
Query 4365 LKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTGTSTDVV 4423
L + VC VCG W+ CSC + +QS D +FLNRV G S ARL PC +G STDV
Sbjct 4343 LTHDVCQVCGFWRDGSCSCVST-DTTVQSKDT-NFLNRVRGTSVDARLVPCASGLSTDVQ 4400
Query 4424 YRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLK 4483
RAFDI N VAG LK NCCRFQ DE+ + +D +FVVKR + Y E Y +K
Sbjct 4401 LRAFDICNASVAGIGLHLKVNCCRFQRVDENGDKLDQFFVVKRTDLTIYNREMECYERVK 4460
Query 4484 DCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNC 4543
DC VA+HDFF F ++G VPHI R+ LTKYTM DL YALRHFD +C L +IL Y
Sbjct 4461 DCKFVAEHDFFTFDVEGSRVPHIVRKDLTKYTMLDLCYALRHFDRNDCMLLCDILSIYAG 4520
Query 4544 CDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQD 4603
C+ YF KKDWYDFVENPDI+ VY LG +AL+ +F D + G+VG+LTLDNQD
Sbjct 4521 CEQSYFTKKDWYDFVENPDIINVYKKLGPIFNRALVSATEFADKLVEVGLVGILTLDNQD 4580
Query 4604 LNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLL 4663
LNG WYDFGD++ PG GV + DSYYS +MP+LT+ AL E +V+ Y +DL+
Sbjct 4581 LNGKWYDFGDYVIAAPGCGVAIADSYYSYMMPMLTMCHALDCELYVNN----AYRLFDLV 4636
Query 4664 KYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVR 4723
+YDFT+ +L+LF++YFK+W YHPN V+C DDRCI+ CANFN+LFS V P T FGPLVR
Sbjct 4637 QYDFTDYKLELFNKYFKHWSMPYHPNTVDCQDDRCIIRCANFNILFSMVLPNTCFGPLVR 4696
Query 4724 KIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDK 4783
+IFVDGVPFVVS GYH++ELG+V N DV+ H RLS K+LL+YAADPA+H AS + L D
Sbjct 4697 QIFVDGVPFVVSIGYHYKELGIVMNMDVDTHRYRLSLKDLLLYAADPALHVASASALYDL 4756
Query 4784 RTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAIS 4843
RT CFSVAA+T+ V FQTVKPGNFN+DFYDF +SKG KEGSSV+LKHFFF QDGNAAI+
Sbjct 4757 RTCCFSVAAITSGVKFQTVKPGNFNQDFYDFILSKGLLKEGSSVDLKHFFFTQDGNAAIT 4816
Query 4844 DYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGK 4903
DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGGCI A+QVIVNN DKSAG+PFNK+GK
Sbjct 4817 DYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGGCIPASQVIVNNYDKSAGYPFNKFGK 4876
Query 4904 ARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQF 4963
ARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI STMT R F
Sbjct 4877 ARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILSTMTGRMF 4936
Query 4964 HQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLR 5023
HQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV+NP LMGWDYPKCDRAMPN+LR
Sbjct 4937 HQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDNPVLMGWDYPKCDRAMPNILR 4996
Query 5024 IMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYAN 5083
I++SLVLARKH CCS S RFYRLANE AQVLSE+VMCGG YVKPGGTSSGDATTA+AN
Sbjct 4997 IVSSLVLARKHEACCSQSDRFYRLANEYAQVLSEIVMCGGCYYVKPGGTSSGDATTAFAN 5056
Query 5084 SVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRK 5143
SVFNICQAV+ANV AL+S +GNKI D +R LQ RLY +YR+ VD+ FV E+Y +L K
Sbjct 5057 SVFNICQAVSANVCALMSCNGNKIEDLSIRALQKRLYSHVYRSDMVDSTFVTEYYEFLNK 5116
Query 5144 HFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHE 5203
HFSMMILSDD VVC+NS YAS+G +A+I F+ VLYYQNNVFMSE+KCW E D+ GPHE
Sbjct 5117 HFSMMILSDDGVVCYNSDYASKGYIANISAFQQVLYYQNNVFMSESKCWVENDINNGPHE 5176
Query 5204 FCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTK 5263
FCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFVSLAIDAYPL
Sbjct 5177 FCSQHTMLVKMDGDDVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFVSLAIDAYPLVY 5236
Query 5264 HPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVL 5323
H N+EY VF +YL+YI+KL++EL +LD YSV+L+ + ++ + FY+ MY V+
Sbjct 5237 HENEEYQKVFRVYLEYIKKLYNELGNQILDSYSVILSTCDGQKFTDESFYKNMYLRSAVM 5296
Query 5324 QAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTD 5383
Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV++T HK VLSV+PYVCNAPGCDV D
Sbjct 5297 QSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHVMATDHKYVLSVSPYVCNAPGCDVND 5356
Query 5384 VTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGD 5443
VT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS + DFN IA+C WT+ D
Sbjct 5357 VTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYIDDFNRIASCKWTDVDD 5416
Query 5444 YILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRN 5503
YILAN CTERLKLFAAET KATEE FK SY AT++E++S+REL LSWE+GK +PPLN+N
Sbjct 5417 YILANECTERLKLFAAETQKATEEAFKQSYASATIQEIVSERELILSWEIGKVKPPLNKN 5476
Query 5504 YVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPT 5563
YVFTGY TKN K +GEY F+K + + V YR TTTYKL+VGD FVLTSH+V LSAPT
Sbjct 5477 YVFTGYHFTKNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFVLTSHSVANLSAPT 5536
Query 5564 LVPQEHYV--RITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLAL 5621
LVPQE+Y R +Y L + F +NV NYQ +GM++Y T+QGPPGTGKSH AIGLA+
Sbjct 5537 LVPQENYSSIRFASVYSVL---ETFQNNVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAV 5593
Query 5622 YYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVF 5681
YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RVEC+DKFK+N T +YVF
Sbjct 5594 YYCTARVVYTAASHAAVDALCEKAYKFLNINDCTRIVPAKVRVECYDKFKINDTTRKYVF 5653
Query 5682 CTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTL 5741
T+NALPE DIVV DE+SM TNY+LSV+NAR+RAKHYVYIGDPAQLPAPR LL+KGTL
Sbjct 5654 TTINALPEMVTDIVVVDEVSMLTNYELSVINARIRAKHYVYIGDPAQLPAPRVLLSKGTL 5713
Query 5742 EPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYK 5801
EP+YFN+V +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA + S+ CFK++YK
Sbjct 5714 EPKYFNTVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYENKLKAKNESSSLCFKVYYK 5773
Query 5802 GVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQ 5861
GV TH+ SSA+N QI ++ +FL NP W KAVFISPYNSQN A ++LGL TQTVDS+Q
Sbjct 5774 GVTTHESSSAVNMQQIYLINKFLKANPLWHKAVFISPYNSQNFAARRVLGLQTQTVDSAQ 5833
Query 5862 GSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNV 5921
GSEYDYVI++QT ETAHS NVNRFNVAITRAK GILC+MS+ L++ LQFT+L + +
Sbjct 5834 GSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSNMQLFEALQFTTLTVDKVPQ 5893
Query 5922 A-TLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRL 5979
A + + T LFKDCSK +G HP AP+ L+VD K+K T L V + +TY RL
Sbjct 5894 AVETRVQCSTNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRL 5953
Query 5980 ISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTG 6039
S+MGFK++ ++GY +FIT+EEA++ VRAW+GFD EG HATR+++GTN PLQLGFSTG
Sbjct 5954 TSLMGFKLDVTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTG 6013
Query 6040 VNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTL 6099
++ V TG + F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L
Sbjct 6014 IDFVVEATGLFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHL 6073
Query 6100 KNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFD 6159
+LSD VV V WA FELT ++YF K+G E +C +C +RAT +++ + Y CW HS+ D
Sbjct 6074 IDLSDCVVLVTWAANFELTCLRYFAKVGREISCNVCTKRATAYNSRTGYYGCWRHSVTCD 6133
Query 6160 YVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTI 6219
Y+YNP ++D+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +
Sbjct 6134 YLYNPLIVDIQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNV 6193
Query 6220 EYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQ 6279
EYPII +EL IN +CR +Q +++KAA+L +++ + +DIGNPKAI CV D ++KFYDAQ
Sbjct 6194 EYPIISNELSINTSCRVLQRVMLKAAMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQ 6251
Query 6280 PCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGC 6339
P ++ L Y + H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC
Sbjct 6252 PI---VKSVKTLLYFFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGC 6308
Query 6340 DGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCI 6399
+GGSLYVNKHAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCI
Sbjct 6309 NGGSLYVNKHAFHTKPFSRAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCI 6368
Query 6400 TRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAF 6459
TRCNL GAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQSLENV +
Sbjct 6369 TRCNLVGAVCLKHAEEYREYLNSYNTATTAGFTFWVYKTFDFYNLWNTFTKLQSLENVVY 6428
Query 6460 NVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVP 6519
N+V GH+ GQ GE+P +IIN+ V K+D DV +F N TT P NVA EL+AKR+I+ P
Sbjct 6429 NLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHP 6488
Query 6520 EVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRV 6579
E+K+ NL +D+ VIWDY R++ +T GVC TD+ L V FDGR
Sbjct 6489 ELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------FIDKLNVLFDGRD 6542
Query 6580 DGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI---GEAVKTQFNYYKKVDG 6636
+G ++ F+ + NGV I+ VK L GP +A LNGV + F K+
Sbjct 6543 NGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQD 6602
Query 6637 VVQQLPE-------------------------------TYFTQSRNLQEFKPRSQMEIDF 6665
V+ + T FTQSR + F R+ ME DF
Sbjct 6603 VIFSQFDSLRVSSNQSPQGNLGSNEPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDF 6662
Query 6666 LELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDS 6725
+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S +++F+ DS
Sbjct 6663 IALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDS 6722
Query 6726 TVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWC 6785
++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+ + FMLWC
Sbjct 6723 SIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWC 6782
Query 6786 KDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKY 6845
D V TFY +LQ++ W+PG +MP LYK +E+ L NYG TLP G MMNVAKY
Sbjct 6783 NDEKVMTFYLRLQAASDWKPGYSMPVLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKY 6842
Query 6846 TQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDA 6905
TQLCQYLNT TLAVP NMRV+H GAGS+KGVAPG+AVLRQWLP GT+LVD+DL FVSD+
Sbjct 6843 TQLCQYLNTTTLAVPVNMRVLHLGAGSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDS 6902
Query 6906 DSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSV 6965
+T GDC T+ +WDLIISDMYDP TKN+ + N SK+GFFTYIC I+ KLALGGSV
Sbjct 6903 VATYFGDCITLPFDCQWDLIISDMYDPITKNIGEYNVSKDGFFTYICHMIRDKLALGGSV 6962
Query 6966 AIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHAN 7025
AIKITE SWNA+LYKLMG+FA+WT F TN NASSSE FLIG NYLGKP+ +IDG VMHAN
Sbjct 6963 AIKITEFSWNAELYKLMGYFAFWTVFCTNANASSSEGFLIGINYLGKPKVEIDGNVMHAN 7022
Query 7026 YIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNR 7085
Y+FWRN+ +YSLFDM+KFPLKL GTAV++L+ QINDM+ SLL KG+L++R+ N+
Sbjct 7023 YLFWRNSTVWNGGAYSLFDMAKFPLKLAGTAVINLRADQINDMVYSLLEKGKLLVRDTNK 7082
Query 7086 VVISSDVLVN 7095
V D +VN
Sbjct 7083 EVFVGDSMVN 7092
Score = 653 bits (1685), Expect = 0.0, Method: Composition-based stats.
Identities = 226/1040 (22%), Positives = 376/1040 (36%), Gaps = 183/1040 (18%)
Query 43 RQHLKDGTCGLVEVE----------KGVLPQLEQPYVFIKRSDA---RTAPHGHVMVEL- 88
+ L+ LV +G P +F +RS R A + HV +L
Sbjct 94 QDALQSREAVLVTPPLGMSLEACYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAYQLY 153
Query 89 VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKNGNKGA-------GGHS 135
+ + G+ +G +G+ +G ++P + +PV RK + LRK G KGA GG
Sbjct 154 MIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVPWVMYLRKCGEKGAYNKDHKRGGFE 211
Query 136 YGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
+ + K D D + +P F + L+R G YVD C G
Sbjct 212 HVYNFKVEDAYDLVHDEPKGKFSKK---------AYALIRGYRGVKPLLYVDQYGCDYTG 262
Query 196 ---YPLECIKDLLARAGKASCTL-SEQLDFIDTKRGVYCCREHEHEIAWYTERSEK-SYE 250
LE D + KA + S++L F + +AW+ R +
Sbjct 263 GLADGLEAYADKTLQEMKALFPIWSQELPF-------------DVTVAWHVVRDPRYVMR 309
Query 251 LQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFM---- 297
LQ+ I+ D +G P V+ +SII + + L M
Sbjct 310 LQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYADDSII------LRQHNLVDIMSCFY 363
Query 298 ----GRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCEF-CGTENLT 350
+ + Y V +C + + C D C W G+ + CG T
Sbjct 364 MEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCDFKGWVPGNMIDGFACTTCGHVYET 422
Query 351 KEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGC 409
+ A + G LP N V+ A + G + S Y G + FGGC
Sbjct 423 GDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFTLY------------GQTVVYFGGC 469
Query 410 VFSYVGCHNKCAYWVPRASANI----GCNHTGVVGEGSEGLNDNL-LEILQKEKVNINIV 464
V+ + N W+P +++ G +TGVVG + NL + L + V +
Sbjct 470 VY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGCKAIVKETNLICKALYLDYVQ-HKC 524
Query 465 GDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNI- 523
G+ E + + S L+ +K ++E+ F + + K + +
Sbjct 525 GNLHQRELLGV---------SDVWHKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVC 575
Query 524 --GEQKSILSPLY-----------AFASEAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
G +L L AF A ++ ++ S++ E S+ L AAI L
Sbjct 576 ADGFMPFLLDDLVPRAYYLAVSGQAFCDYAGKICHAVVSKSKELLDVSLDSL-GAAIHYL 634
Query 571 DGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDW 630
+ +++D SD T+ +V + T+ L VL
Sbjct 635 NS------KIVDLAQHFSDFGTS-------FVSKIVHFFKTFTTSTALAFAWVLFHVLHG 681
Query 631 LEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCA 690
+ + F+++ I ++ S V + AK + +S++ F +
Sbjct 682 AYIVVESDIYFVKN---IPRYASA-----VAQAFRSVAKVVLDSLRVTFIDGLSCFKIGR 733
Query 691 DSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMP---LKAPKEIIFLEGETL 747
I + G+K+ + G + HS L + L MP K ++ I+L+G
Sbjct 734 RRICLSGSKIYEVERG---LLHSSQL------PLDVYDLTMPSQVQKTKQKPIYLKGSGS 784
Query 748 PTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMM 807
+ V + T L P E P V +CI + + + Y + +
Sbjct 785 DFSLADSVVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDGHV 839
Query 808 VTNNTFTLKGGAPTKVTFGDDT-VIEVQGY-KSVNITFELDERIDKVLNEKCSAYTVELG 865
+ A VTF + V E+ K++ + +ELD+ + +LN C + V+
Sbjct 840 GLLDQAWRVPCAGRCVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGVFEVDDT 899
Query 866 TEVNEFACVVADAVIKTLQPVSEL---LTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
++ EF VV DA+ + L P EL + L + + +LFDE+GE LA +YC
Sbjct 900 VDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGEEVLAPKLYC 959
Query 923 SFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQE--EDWL 980
+F P++D D EE E D G A + EE E ED L
Sbjct 960 AFTAPEDD----DFLEESGVEEDDVEGEETD---LTVTSAGEPCVASEQEESSEILEDTL 1012
Query 981 DDDSQQTVGQQDGSEDNQTT 1000
DD ED Q +
Sbjct 1013 DDGPCVETSDSQVEEDVQMS 1032
Score = 194 bits (493), Expect = 3e-47, Method: Composition-based stats.
Identities = 59/251 (24%), Positives = 111/251 (44%), Gaps = 17/251 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D +
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + T + V L ++ +D + ++ K++ ++++
Sbjct 1392 AGIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLISKCQITAVEGTKKLAERLSFNVGR 1451
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+ +K + L++ L ++ L ++ N ++
Sbjct 1452 SIVYETDANKLILSNDVA--------FVSTFNVLQDVLSLRHDIALDDDARTFVQSNVDV 1503
Query 1264 HPDSATLVSDI 1274
P+ +V+
Sbjct 1504 VPEGWRVVNKF 1514
Score = 48.9 bits (115), Expect = 0.003, Method: Composition-based stats.
Identities = 41/196 (21%), Positives = 73/196 (37%), Gaps = 22/196 (11%)
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
++ +V L K NNC+L + L +Q++ +F LQD + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1717 Y--CNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
N V + G V + + L + V C C LKG++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1775 SYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCG 1834
V C CG+ L+ + PF A + LK F Y+
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPFT------AHFALKDKLFCAFITKRSVYKAA 1216
Query 1835 HYKHITSKETLYCIDG 1850
+ ++ +DG
Sbjct 1217 CVVDVNDSHSMAVVDG 1232
>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095
Score = 7737 bits (20075), Expect = 0.0, Method: Composition-based stats.
Identities = 2748/5651 (49%), Positives = 3674/5651 (65%), Gaps = 173/5651 (3%)
Query 1531 GDKSVYYTSNPTTFHLDG--EVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSM 1588
G + + G T +K L + + + TVD +N + V +
Sbjct 1530 GGIDICSQDKVFGYVQQGIFNKATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGE 1585
Query 1589 TYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMS 1648
++G+ G + DG +VTK K +++GK F+ N + ++A D L Y +
Sbjct 1586 SFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYN 1645
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAA 1708
L + KW+ + K A+NNC++ + L LQ + L F Q+A+ R+G A
Sbjct 1646 MLVNCFKWQVVVNGKYFTFKQANNNCFVNVSCLMLQSLHLTFKIVQWQEAWLEFRSGRPA 1705
Query 1709 NFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAV 1768
F AL+LA G+ D R+ + +F +L + CK CG +Q G++AV
Sbjct 1706 RFVALVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGLDAV 1764
Query 1769 MYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYT 1828
M+ GTLS E + G + C+CGK+ + V+ + PF++ S PA +L G + A+ +
Sbjct 1765 MHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLICSNTPASVKLPKGVGS-ANIFI 1822
Query 1829 GNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGV 1887
G+ GHY H+ +++ D + + K ++ G ++D Y +N T TY LD V
Sbjct 1823 GD-NVGHYVHVKCEQSYQLYDASNVKKVTDVTGKLSDCLYLKNLKQTFKSVLTTYYLDDV 1881
Query 1888 VCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNASFDNFKFVCDNIKFADDLNQLTG 1946
E P L YY Y+T++ I + + NFK + + D LN G
Sbjct 1882 KKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGVYTNFKLIGHTV--CDSLNSKLG 1939
Query 1947 YKKPA-SRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY 2003
+ E K+T +P GDVV + Y +++G KP++W H + N TY
Sbjct 1940 FDSSKEFVEYKITEWPTATGDVVLANDDLYVKRYERGCITFGKPVIWLSHEKASLNSLTY 1999
Query 2004 KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLE 2063
++ + N FDVLK +D + + K E I L
Sbjct 2000 ----------FNRPLLVDDNKFDVLKVDDVDDSGDSSESGAK-------ETKEINIIKLS 2042
Query 2064 CNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTL- 2122
K +V +I+ + K + + D+ ++ ++ N LSR + + T+
Sbjct 2043 GVKKPFKVEDSVIVNDDTSETKYVKSLSIVDVYDMWLTGCKYVVRTANALSRAVNVPTIR 2102
Query 2123 --ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLC 2180
G+ V S+P D + VV N + C N++ + F LL
Sbjct 2103 KFIKFGMTLV-SIPIDLLNLREIKPAVNVVKAVRNKTS-----ACFNFIKWLFVLLFGWI 2156
Query 2181 TFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINII--IWFLLLSV 2238
+ K T IA + + +F K ++ II I+ L +
Sbjct 2157 KISA----DNKVIYTTEIASKLTCKLVALAFKNAFLTFKWSMVARGACIIATIFLLWFNF 2212
Query 2239 CLGSLIYSTAALG--------------VLMSNLGMPSYCTGYREGYLNSTNVTIATYCTG 2284
++I+S L + + + + C Y + YC G
Sbjct 2213 IYANVIFSDFYLPKIGFLPTFVGKIAQWIKNTFSLVTICDLYSIQDVGF----KNQYCNG 2268
Query 2285 SIPCSVCLSGLDSLDTYPSLETIQITISS--FKWDLTAFGLVAEWFLAYILFTRFFYVLG 2342
SI C CL+G D LD Y +++ +Q F +V E ++Y L+T +FY L
Sbjct 2269 SIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF 2328
Query 2343 LAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
+Q+ ++ F+ ++ W L++ L M P +R YI ASF ++ + HV
Sbjct 2329 ALISIQILTTWLPELFMLSTLHWSFRLLVALANMLPAHVFMRFYIIIASFIKLFSLFKHV 2388
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GC+ S C+ CYKRNR+ RV+C+TIV G+ R + V ANGG GFC H WNC++CD++
Sbjct 2389 AYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKP 2448
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G+TFI+ E A DLS + KRPI PTD + + V V S+ L++D+ GQ+ Y+ + S
Sbjct 2449 GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCSMRLFYDRDGQRIYDDVNASL 2508
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FV+ NL + K ++V+V + + ++++ +A+V+Y+Q + +PIL++D+ L++
Sbjct 2509 FVDYSNLLHSKVKSVPNMHVVVVENDA--DKANFLNAAVFYAQSLFRPILMVDKNLITTA 2566
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
V MFD YV+TF S F+V + L L+ATA + + + + VL TF+S AR+
Sbjct 2567 NTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQIYKVLDTFLSCARKS 2626
Query 2641 F-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHI 2699
+DSDV+TK + + + + + +E+T +SCNN + TY K +N+ DLG I SA+H+
Sbjct 2627 CSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKSDNIVAADLGVLIQNSAKHV 2686
Query 2700 NAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIA 2759
VAK ++ IW+V F S + +++ A K L KLT V+V+TT +
Sbjct 2687 QGNVAKIAGVSCIWSVDAFNQFSSDFQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFS 2746
Query 2760 LKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRD 2819
LKGG + + ++ ++LV + + P + + K YK +D GV RD
Sbjct 2747 LKGGAVFSYFVYVCFVLSLVCFI---GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRD 2803
Query 2820 IASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILRTT 2877
++ D CFANK FD W+ G Y+N ACP++ AVI ++ G V +P +LR
Sbjct 2804 VSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACPIVVAVIDQDFGSTVFNVPTKVLRY- 2862
Query 2878 NGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTN 2937
LHF+ SA G CYTP I Y++F S CVL++ CT+F A G P PYCY
Sbjct 2863 GYHVLHFITHALSADGVQCYTPHSQISYSNFYASGCVLSSACTMFTMADGSPQPYCYTDG 2922
Query 2938 VLEGSVAYESLRPDTRYVLMDG-SIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGV 2996
+++ + Y SL P RY L + I+FP EG VRVV T YCR G CE ++ G+
Sbjct 2923 LMQNASLYSSLVPHVRYNLANAKGFIRFPEVLREGLVRVVRTRSMSYCRVGLCEEADEGI 2982
Query 2997 CVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIV 3056
C + +G WVLNNDYYRSLPG FCG D +L+ +F L QP+ L ++AS +AG I+A++
Sbjct 2983 CFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVI 3042
Query 3057 VTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYL 3116
V + YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L VY++ Y Y T Y
Sbjct 3043 VVLVFYYLIKLKRAFGDYTSVVFVNVIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYF 3102
Query 3117 TNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE 3176
+++S + H+QW+VM+ ++P W + YI + + H +W FS R++ + S TFE
Sbjct 3103 PSEISVIMHLQWLVMYGTIMPLWFCLLYIAVVVSNHAFWVFS--YCRKLGTSVRSDGTFE 3160
Query 3177 EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAK 3236
E AL TF++ K+ Y KL++ L +NRYL+LYNKY+Y+SG MDT +YREAAC LAK
Sbjct 3161 EMALTTFMITKDSYCKLKNS--LSDVAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAK 3218
Query 3237 ALNDF-SNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
A++ F +N+GSDVLYQPP S++++ LQSG KM P+ KVE C+V VT G TLNGLWL
Sbjct 3219 AMDTFTNNNGSDVLYQPPTASVSTSFLQSGIVKMVNPTSKVEPCVVSVTYGNMTLNGLWL 3278
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVD 3355
DD VYCPRHVIC++ DM NP+Y +LL R ++ +F V + L V+ + M+ C+L L V
Sbjct 3279 DDKVYCPRHVICSASDMTNPDYTNLLCRVTSSDFTVLFDRLSLTVMSYQMRGCMLVLTVT 3338
Query 3356 TANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNI 3415
N +TPKY F ++PG+TF+VLA YNG P G + MR ++TIKGSFL GSCGSVG+ I
Sbjct 3339 LQNSRTPKYTFGVVKPGETFTVLAAYNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVI 3398
Query 3416 DYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAV 3475
DCV F YMH +EL TG H GTD G+FYGP+ D Q Q D +VN LAWLYAA+
Sbjct 3399 MGDCVKFVYMHQLELSTGCHTGTDFNGDFYGPYKDAQVVQLPIQDYIQSVNFLAWLYAAI 3458
Query 3476 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL 3535
+N WF+ ++ DFN+ A+ + + D V + L++ TG+++ + A++K L
Sbjct 3459 LNNCNWFIQSDKCSVEDFNVWALSNGFSQVKSDLV--IDALASMTGVSLETLLAAIKRL- 3515
Query 3536 QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLV 3595
+NG GR I+GS EDE TP DV +Q +G+ QS R KGT W++ + ++
Sbjct 3516 KNGFQGRQIMGSCSFEDELTPSDVYQQLAGIKLQSKRTRLFKGTVCWIMASTFLFSCIIT 3575
Query 3596 QSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN-MVY 3654
+W++F ++ N F + + + AM+ VKHKH +L +++ P L T+ Y N +V
Sbjct 3576 AFVKWTMFMYVTTNMF-SITFCALCVISLAMLLVKHKHLYLTMYITPVLFTLLYNNYLVV 3634
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL-LILMTARTVYDDGARRVWTLMN 3713
++ + WL S+ + D V+Y +++ ++ +T R++ D + +
Sbjct 3635 YKHTFRGYVYAWLSYYVPSVE-YTYTDEVIYGMLLLVGMVFVTLRSINHDLFSFIMFVGR 3693
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
++++ Y G+ L++ I + ++ S+ Y+ M +A+ ++ V ++F
Sbjct 3694 LISVFSLWYKGSNLEEEILL--MLASLFGTYTWTTVLSMAVAK-VIAKWVAVNVLYFTDI 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
++ ++L Y F+GY +CY+GLF L+N FR+ LGVY+Y +S QE RYMN+ GL PPKN
Sbjct 3751 PQIKIVLLCYLFIGYIISCYWGLFSLMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKN 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
S +A LN KLLG+GG P I+V+ QSK++DVKC +VVLL+ LQ L V S+SKLW C
Sbjct 3811 SFEALMLNFKLLGIGGVPIIEVSQFQSKLTDVKCANVVLLNCLQHLHVASNSKLWHYCST 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQAIASE 3947
LHN+IL D + AFEK+ LL VL + AVD I ++C++ + LQA+ SE
Sbjct 3871 LHNEILATSDLSVAFEKLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSE 3930
Query 3948 FSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMAD 4006
F ++ S+ + A++ ++A +G + + LK+L+K+ N+AKS ++RD A+ +KLE+MAD
Sbjct 3931 FVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAYERDRAVAKKLERMAD 3990
Query 4007 QAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTT 4066
A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 3991 LALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLA 4050
Query 4067 AAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPL 4126
A L +++PD + Y D TYA +W+IQ + D+D QL+EIS D + WPL
Sbjct 4051 ANTLNIIVPDKSVYDQIVDNIYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN----WPL 4106
Query 4127 IVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLAL 4184
++ A R N SA LQNNEL P L+ +G QT T YYN + G+ V A+
Sbjct 4107 VIIANRYNEVSATVLQNNELMPAKLKIQVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAI 4164
Query 4185 LSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLG 4244
LSD+ LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V+G
Sbjct 4165 LSDVDGLKYTKILKDDGN-FVVLELDPPCKFTVQDAKGLKIKYLYFVKGCNTLARGWVVG 4223
Query 4245 SLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGT 4304
++++TVRLQAG ATE +NS++LS CAF+VD K Y D++ GG PI NCVKMLC H GT
Sbjct 4224 TISSTVRLQAGTATEYASNSSILSLCAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGT 4283
Query 4305 GQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFT 4364
G AITV P+A Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV +
Sbjct 4284 GMAITVKPDATTSQDSYGGASVCIYCRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYV 4342
Query 4365 LKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTGTSTDVV 4423
L + VC VCG W+ CSC + +QS D +FLNRV G S ARL PC +G STDV
Sbjct 4343 LTHDVCRVCGFWRDGSCSCVST-DTTVQSKDT-NFLNRVRGASVDARLVPCASGLSTDVQ 4400
Query 4424 YRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLK 4483
RAFDIYN VAG LK NCCRFQ DE+ + +D +FVVKR + Y E Y +K
Sbjct 4401 LRAFDIYNASVAGIGLHLKVNCCRFQRVDENGDKLDQFFVVKRTDLTIYNREMKCYERVK 4460
Query 4484 DCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNC 4543
DC VA+HDFF F ++G VPHI R+ LTKYTM DL YALRHFD +C L +IL Y
Sbjct 4461 DCKFVAEHDFFTFDVEGSRVPHIVRKDLTKYTMLDLCYALRHFDRNDCMLLCDILSIYAG 4520
Query 4544 CDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQD 4603
C+ YF KKDWYDFVENPDI+ VY LG +AL+ +F D + G+VGVLTLDNQD
Sbjct 4521 CEQSYFTKKDWYDFVENPDIINVYKKLGPIFNRALVSATEFADKLVEVGLVGVLTLDNQD 4580
Query 4604 LNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLL 4663
LNG WYDFGD++ PG GV + DSYYS +MP+LT+ AL E +V+ Y +DL+
Sbjct 4581 LNGKWYDFGDYVIAAPGCGVAIADSYYSYIMPMLTMCHALDCELYVNN----AYRLFDLV 4636
Query 4664 KYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVR 4723
+YDFT+ +L+LF++YFK+W YHPN V+C DDRCI+HCANFN+LFS V P T FGPLVR
Sbjct 4637 QYDFTDYKLELFNKYFKHWSMPYHPNTVDCQDDRCIIHCANFNILFSMVLPNTCFGPLVR 4696
Query 4724 KIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDK 4783
+IFVDGVPFVVS GYH++ELG+V N DV+ H RLS K+LL+YAADPA+H AS + L D
Sbjct 4697 QIFVDGVPFVVSIGYHYKELGIVMNMDVDTHRYRLSLKDLLLYAADPALHVASASALYDL 4756
Query 4784 RTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAIS 4843
RT CFSVAA+T+ V FQTVKPGNFN+DFYDF +SKG KEGSSV+LKHFFF QDGNAAI+
Sbjct 4757 RTCCFSVAAITSGVKFQTVKPGNFNQDFYDFVLSKGLLKEGSSVDLKHFFFTQDGNAAIT 4816
Query 4844 DYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGK 4903
DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGGCI A+QVIVNN DKSAG+PFNK+GK
Sbjct 4817 DYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGGCIPASQVIVNNYDKSAGYPFNKFGK 4876
Query 4904 ARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQF 4963
ARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI STMT R F
Sbjct 4877 ARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILSTMTGRMF 4936
Query 4964 HQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLR 5023
HQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV+NP LMGWDYPKCDRAMPN+LR
Sbjct 4937 HQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDNPVLMGWDYPKCDRAMPNILR 4996
Query 5024 IMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYAN 5083
I++SLVLARKH TCCS S RFYRLANECAQVLSE+VMCGG YVKPGGTSSGDATTA+AN
Sbjct 4997 IVSSLVLARKHETCCSQSDRFYRLANECAQVLSEIVMCGGCYYVKPGGTSSGDATTAFAN 5056
Query 5084 SVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRK 5143
SVFNICQAV+ANV AL+S +GNKI D +R LQ RLY +YR+ VD+ FV E+Y +L K
Sbjct 5057 SVFNICQAVSANVCALMSCNGNKIEDLSIRALQKRLYSHVYRSDKVDSTFVTEYYEFLNK 5116
Query 5144 HFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHE 5203
HFSMMILSDD VVC+NS YAS+G +A+I F+ VLYYQNNVFMSE+KCW E D+ GPHE
Sbjct 5117 HFSMMILSDDGVVCYNSDYASKGYIANISAFQQVLYYQNNVFMSESKCWVEHDINNGPHE 5176
Query 5204 FCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTK 5263
FCSQHTMLVK D VYLPYP+PSRILGAGCFVDD++KTD L+IERFVSLAIDAYPL
Sbjct 5177 FCSQHTMLVKMDGDDVYLPYPNPSRILGAGCFVDDLLKTDSVLLIERFVSLAIDAYPLVY 5236
Query 5264 HPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVL 5323
H N+EY VF +YL YI+KL+++L +LD YSV+L+ + ++ + FY+ MY V+
Sbjct 5237 HENEEYQKVFRVYLAYIKKLYNDLGNQILDSYSVILSTCDGQKFTDESFYKNMYLRSAVM 5296
Query 5324 QAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTD 5383
Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV++T HK VLSV+PYVCNAPGCDV D
Sbjct 5297 QSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHVMATDHKYVLSVSPYVCNAPGCDVND 5356
Query 5384 VTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGD 5443
VT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS + DFN IA+C WT+ D
Sbjct 5357 VTKLYLGGMSYYCEDHKPQYSFKLVMNGLVFGLYKQSCTGSPYIDDFNRIASCKWTDVDD 5416
Query 5444 YILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRN 5503
YILAN CTERLKLFAAET KATEE FK SY AT++E++S+REL LSWE+GK +PPLN+N
Sbjct 5417 YILANECTERLKLFAAETQKATEEAFKQSYASATIQEIVSERELILSWEIGKVKPPLNKN 5476
Query 5504 YVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPT 5563
YVFTGY TKN K +GEY F+K + + V YR TTTYKL+VGD FVLTSH+V LSAPT
Sbjct 5477 YVFTGYHFTKNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFVLTSHSVANLSAPT 5536
Query 5564 LVPQEHYV--RITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLAL 5621
LVPQE+Y R +Y L + F +NV NYQ +GM++Y T+QGPPGTGKSH AIGLA+
Sbjct 5537 LVPQENYSSIRFASVYSVL---ETFQNNVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAV 5593
Query 5622 YYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVF 5681
+Y +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RVEC+DKFK+N T +YVF
Sbjct 5594 FYCTARVVYTAASHAAVDALCEKAYKFLNINDCTRIVPAKVRVECYDKFKINDTTRKYVF 5653
Query 5682 CTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTL 5741
T+NALPE DIVV DE+SM TNY+LSV+NAR+RAKHYVYIGDPAQLPAPR LL+KGTL
Sbjct 5654 TTINALPEMVTDIVVVDEVSMLTNYELSVINARIRAKHYVYIGDPAQLPAPRVLLSKGTL 5713
Query 5742 EPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYK 5801
EP+YFN+V +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA + S CFK++YK
Sbjct 5714 EPKYFNTVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYENKLKAKNESSLLCFKVYYK 5773
Query 5802 GVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQ 5861
GV TH+ SSA+N QI ++ +FL NP W KAVFISPYNSQN A ++LGL TQTVDS+Q
Sbjct 5774 GVTTHESSSAVNMQQIYLINKFLKANPLWHKAVFISPYNSQNFAAKRVLGLQTQTVDSAQ 5833
Query 5862 GSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNV 5921
GSEYDYVI++QT ETAHS NVNRFNVAITRAK GILC+MS+ L++ LQFT+L + +
Sbjct 5834 GSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSNMQLFEALQFTTLTLDKVPQ 5893
Query 5922 A-TLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRL 5979
A + + T LFKDCSK +G HP AP+ L+VD K+K T L V + +TY RL
Sbjct 5894 AVETKVQCSTNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRL 5953
Query 5980 ISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTG 6039
IS+MGFK++ ++GY +FIT+EEA++ VRAW+GFD EG HAT +++GTN PLQLGFSTG
Sbjct 5954 ISLMGFKLDVTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATLDSIGTNFPLQLGFSTG 6013
Query 6040 VNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTL 6099
++ V TG + F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L
Sbjct 6014 IDFVVEATGLFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGHRWDVVRPRIVQMFADHL 6073
Query 6100 KNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFD 6159
+LSD VV V WA FELT ++YF K+G E +C +C +RAT +++ + Y CW HS+ D
Sbjct 6074 IDLSDCVVLVTWAANFELTCLRYFAKVGREISCNVCTKRATVYNSRTGYYGCWRHSVTCD 6133
Query 6160 YVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTI 6219
Y+YNP ++D+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +
Sbjct 6134 YLYNPLIVDIQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNV 6193
Query 6220 EYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQ 6279
EYPII +EL IN +CR +Q +++KAA+L +++ + +DIGNPK I CV D ++KFYDAQ
Sbjct 6194 EYPIISNELSINTSCRVLQRVILKAAMLCNRYTLCYDIGNPKGIACVK--DFDFKFYDAQ 6251
Query 6280 PCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGC 6339
P ++ L YS+ H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC
Sbjct 6252 PI---VKSVKTLLYSFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGC 6308
Query 6340 DGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCI 6399
+GGSLYVNKHAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCI
Sbjct 6309 NGGSLYVNKHAFHTKPFARAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCI 6368
Query 6400 TRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAF 6459
TRCNLGGAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQSLENV +
Sbjct 6369 TRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTKLQSLENVVY 6428
Query 6460 NVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVP 6519
N+V GH+ GQ GE+P +IIN+ V TK+D DV +F N TT P NVA EL+AKR+++ P
Sbjct 6429 NLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHP 6488
Query 6520 EVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRV 6579
E+K+ NL +D+ VIWDY R++ +T GVC TD+ L V FDGR
Sbjct 6489 ELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------FIDKLNVLFDGRD 6542
Query 6580 DGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI---GEAVKTQFNYYKKVDG 6636
+G + F+ + NGV I+ VK L GP +A LNGV + F K+
Sbjct 6543 NGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQD 6602
Query 6637 VVQQLPE--------------------------------TYFTQSRNLQEFKPRSQMEID 6664
V+ + T FTQSR + F R+ ME D
Sbjct 6603 VIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTCRTDMEKD 6662
Query 6665 FLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMD 6724
F+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S +++F+ D
Sbjct 6663 FIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYD 6722
Query 6725 STVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLW 6784
S++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+ + FMLW
Sbjct 6723 SSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFMLW 6782
Query 6785 CKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAK 6844
C D V TFYP+LQ++ W+PG +MP LYK +E+ L NYG TLP G MMNVAK
Sbjct 6783 CNDEKVMTFYPRLQAASDWKPGYSMPVLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAK 6842
Query 6845 YTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSD 6904
YTQLCQYLNT TLAVP NMRV+H GAGS+KGVAPG+AVLRQWLP GT+LVD+DL FVSD
Sbjct 6843 YTQLCQYLNTTTLAVPVNMRVLHLGAGSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSD 6902
Query 6905 ADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGS 6964
+ +T GDC T+ +WDLIISDMYDP TKN+ + N SK+GFFTYIC I+ KLALGGS
Sbjct 6903 SVATYFGDCITLPFDCQWDLIISDMYDPITKNIGEYNVSKDGFFTYICHMIRDKLALGGS 6962
Query 6965 VAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHA 7024
VAIKITE SWNA+LYKLMG+FA+WT F TN NASSSE FLIG NYL KP+ +IDG VMHA
Sbjct 6963 VAIKITEFSWNAELYKLMGYFAFWTVFCTNANASSSEGFLIGINYLCKPKVEIDGNVMHA 7022
Query 7025 NYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENN 7084
NY+FWRN+ +YSLFDM+KFPLKL GTAV++L+ QINDM+ SLL KG+L+IR+ N
Sbjct 7023 NYLFWRNSTVWNGGAYSLFDMAKFPLKLAGTAVINLRADQINDMVYSLLEKGKLLIRDTN 7082
Query 7085 RVVISSDVLVN 7095
+ V D LVN
Sbjct 7083 KEVFVGDSLVN 7093
Score = 634 bits (1635), Expect = 5e-180, Method: Composition-based stats.
Identities = 233/1139 (20%), Positives = 405/1139 (36%), Gaps = 210/1139 (18%)
Query 43 RQHLKDGTCGLVEVE----------KGVLPQLEQPYVFIKRSDA---RTAPHGHVMVEL- 88
+ L+ LV +G P+ +F +RS R + HV +L
Sbjct 94 QDALQSREAVLVTTPLGMSLEACYVRGCNPKGWTMGLFRRRSVCNTGRCTVNKHVAYQLY 153
Query 89 VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKNGNKGA-------GGHS 135
+ + G+ G +G+ +G ++P + +PV RK + LRK G KGA GG
Sbjct 154 MIDPAGVCLG-AGQFVGWVIP-LAFMPVQSRKFIVPWVMYLRKRGEKGAYNKDHGCGGFG 211
Query 136 YGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
+ D K D D++ +P F + L+R G YVD C G
Sbjct 212 HVYDFKVEDAYDQVHDEPKGKFSKK---------AYALIRGYRGVKPLLYVDQYGCDYTG 262
Query 196 ---YPLECIKDLLARAGKASC-TLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEK-SYE 250
LE D + KA T S++L F + +AW+ R +
Sbjct 263 SLADGLEAYADKTLQEMKALFPTWSQELPF-------------DVIVAWHVVRDPRYVMR 309
Query 251 LQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFMG--- 298
LQ+ I D +G P V+ +SII + + L M
Sbjct 310 LQSAATICSVAYVANPTEDLCDGSVVIKEPVHVYADDSII------LRQYNLFDIMSHFY 363
Query 299 -----RIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCEF-CGTENLT 350
+ + Y VA +C + + C D C W G+ + CG
Sbjct 364 MEADTVVNAFYGVA-LKDCGFVMQFGYIDCEQDSCDFKGWIPGNMIDGFACTTCGHVYEV 422
Query 351 KEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGC 409
+ A + G LP N V+ A + G + S Y G + FGGC
Sbjct 423 GDLIAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFTLY------------GQTVVYFGGC 469
Query 410 VFSYVGCHNKCAYWVPRASANI----GCNHTGVVGEGSEGLNDNL-LEILQKEKVNINIV 464
V+ + N W+P +++ +TGV+G + NL + L + V +
Sbjct 470 VY-WSPARN---IWIPILKSSVKSYDSLVYTGVLGCKAIVKETNLICKALYLDYVQ-HKC 524
Query 465 GDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNI- 523
G+ E + + S ++ +K ++E+ F + + K + +
Sbjct 525 GNLHQRELLGV---------SDVWHKQLLINRGVYKPLLENIDYFNMRRAKFSLETFTVC 575
Query 524 --GEQKSILSPLY-----------AFASEAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
G +L L AF A ++ ++ S++ E S+ L AAI L
Sbjct 576 ADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKLCHAVVSKSKELLDVSLDSL-GAAIHYL 634
Query 571 DGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDW 630
+ +++D SD T+ +V + T+ L VL
Sbjct 635 NS------KIVDLAQHFSDFGTS-------FVSKIVHFFKTFTTSTALAFAWVLFHVLHG 681
Query 631 LEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCA 690
+ + F+++ I ++ S V + AK + +S++ F +
Sbjct 682 AYIVVESDIYFVKN---IPRYASA-----VAQAFQSVAKVVLDSLRVTFIDGLSCFKIGR 733
Query 691 DSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMP---LKAPKEIIFLEGETL 747
I + G K+ + G + HS L + L MP KA ++ I+L+G
Sbjct 734 RRICLSGRKIYEVERG---LLHSSQL------PLDVYDLTMPSQVQKAKQKPIYLKGSGS 784
Query 748 PTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMM 807
+ V + T L P E P V +CI + + + Y + + +
Sbjct 785 DFSLADSVVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDDHV 839
Query 808 VTNNTFTLKGGAPTKVTFGDDTVIE--VQGYKSVNITFELDERIDKVLNEKCSAYTVELG 865
+ A +VTF + ++ + K + + +ELD + +LN C + V+
Sbjct 840 GLLDQAWRVPCAGRRVTFKEQPTVKEIISMPKIIKVFYELDNDFNTILNTACGVFEVDDT 899
Query 866 TEVNEFACVVADAVIKTLQPVSEL---LTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
++ EF VV DA+ + L P EL + L + +LFDE+GE A +YC
Sbjct 900 VDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNPLFLFDEAGEEVFAPKLYC 959
Query 923 SFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQE--EDWL 980
+F P++D+ + + EE + + T G A + EE E ED L
Sbjct 960 AFTAPEDDDFLEESDVEEDDVEGEETDLTI-------TSAGQPCVASEQEESSEVLEDTL 1012
Query 981 DDDSQQTVGQQDGSEDNQTT----TIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTD 1036
DD ED + + I + + T + ++V +
Sbjct 1013 DDGPSVETSDSQVEEDVEMSDFVDLESVIQDYENVCFEFYTTEPEFVKVLGLYVPKATRN 1072
Query 1037 NVYIKNADIV---------------------EEAKKVKPTVVVN--AANVYLKHGGGVA 1072
N ++++ V ++ ++ +VN AN+ L GG VA
Sbjct 1073 NCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVNKIPANIVLPQGGYVA 1131
Score = 191 bits (484), Expect = 3e-46, Method: Composition-based stats.
Identities = 59/251 (24%), Positives = 109/251 (43%), Gaps = 17/251 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV DI++ +K VK VVVN AN ++ HGGGVA A+ A E+ + +
Sbjct 1272 CITPNVCFVKGDIIKVSKLVKAEVVVNPANGHMVHGGGVAKAIAVAAGQQFVKETTNMVK 1331
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ G G V +G L K L+VVGP+ + LL+ Y++FN ++ ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYVLLERVYKHFNNYDCVVTTLIS 1391
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + T + V L ++ +D + ++ K++ +++
Sbjct 1392 AGIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLISKCQITAVEGTKKLAARLSFNVGR 1451
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+ +K + L++ L ++ L ++ N ++
Sbjct 1452 SIVYETDANKLILINDVA--------FVSTFNVLQDVLSLRHDIALDDDARTFVQSNVDV 1503
Query 1264 HPDSATLVSDI 1274
P+ +V+
Sbjct 1504 LPEGWRVVNKF 1514
Score = 48.9 bits (115), Expect = 0.002, Method: Composition-based stats.
Identities = 34/150 (23%), Positives = 61/150 (41%), Gaps = 16/150 (11%)
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
++ +V GL K NNC+L + L +Q++ +F LQD + + + F ++
Sbjct 1057 EFVKVLGLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1717 Y--CNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
N + + G V + + L + V C C LKG++A+ + G +
Sbjct 1117 KIPANIVLPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1775 SYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
V C CG+ L+ + PF
Sbjct 1173 --------VSHICKCGESMV--LIDVDVPF 1192
>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152
Score = 7730 bits (20056), Expect = 0.0, Method: Composition-based stats.
Identities = 2746/5676 (48%), Positives = 3667/5676 (65%), Gaps = 178/5676 (3%)
Query 1512 KDWSYSGQ-STQLGIEFLKR----GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLRE 1564
KDW + G++ +K + + DG T + + LL+
Sbjct 1563 KDWRLINKFDVINGVKTVKYFECPNSIYICSQGKDFGYVCDGSFYKATVNQVCVLLA--- 1619
Query 1565 VRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPND 1624
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1620 -KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENL 1678
Query 1625 DTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQ 1684
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1679 SLADISAVQSSFGFDQQQLLAYYNFL-TVCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQ 1737
Query 1685 QIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSC 1744
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1738 HINLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGA 1797
Query 1745 KRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF
Sbjct 1798 ICELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPF 1855
Query 1805 VMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPIT 1864
++ S P +L A+ + G GHY H+ D + K + G +T
Sbjct 1856 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1913
Query 1865 DVFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP-- 1921
D Y +N + T T Y LD V +P L YY + Y+T +PI +P+
Sbjct 1914 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKV 1972
Query 1922 NASFDNFKFVCDNIKFADDLNQLTGYKKP-ASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
+ + NFK V +I LN G+ E KVT +P GDVV Y +
Sbjct 1973 DGVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYF 2030
Query 1981 KGAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDN 2038
KG + KP++W H + N TY ++ ++ N + VL D+
Sbjct 2031 KGCETFGKPVIWLCHDEASLNSLTY----------FNKPSFKSENRYSVLSV------DS 2074
Query 2039 LACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMA 2097
++ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2075 VSEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWD 2134
Query 2098 AYVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT 2154
Y+ + NELSR++ T+ +G+ + ++P D + N+ +
Sbjct 2135 MYLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRDD---NQTLLVPK 2190
Query 2155 NIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEAS 2214
R + ++ + F + L FT T IA ++ L+ +
Sbjct 2191 IFKARAIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNA 2244
Query 2215 FNYLKSPNFSKLIN-----IIIWF--LLLSVCLGSL---------IYSTAALGVLMSNLG 2258
F + F K + WF L ++V I+ + + + G
Sbjct 2245 FQTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFG 2304
Query 2259 MPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKW-- 2316
+ + C Y + + T+ +C GS C +C SG D LDTY +++ +Q +
Sbjct 2305 LVTICDFYSKLGVGFTS----HFCNGSFICELCYSGFDMLDTYAAIDFVQYEVDRRVLFD 2360
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2361 YVSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2420
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2421 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2480
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2481 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2540
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + + + ++
Sbjct 2541 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVESDA--DRANF 2598
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2599 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVN 2658
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2659 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2718
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK+ NI+ IW + F L+ L+ +++ A
Sbjct 2719 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDTFNQLTADLQHKLKKAC 2778
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L ++L+ + + + P
Sbjct 2779 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPT 2835
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ G Y N C
Sbjct 2836 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSFYYHNSMDC 2895
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2896 PIVVAVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2954
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2955 GCVLSSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 3014
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 3015 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQF 3074
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3075 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFL 3134
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3135 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3194
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N + STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3195 NHVLWLFS--YCRKIGVNVCNDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3250
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3251 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3310
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R + +F
Sbjct 3311 VSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDF 3370
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3371 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAF 3430
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3431 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYR 3490
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM + + D
Sbjct 3491 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADL 3550
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3551 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3607
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + + ++ +F M+ V
Sbjct 3608 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYINTH-MIGVTLCVLCFVSFMMLLV 3666
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3667 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGLTYVWLSYFVPAVNFTYVYEVFYGCIL 3726
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3727 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTWTT 3784
Query 3749 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 3808
+ +A+ IV + +F ++ I+L Y F+GY +CY+G F LLN FR+ +
Sbjct 3785 ILSLAIAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPM 3843
Query 3809 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCT 3868
GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3844 GVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCA 3903
Query 3869 SVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD-- 3926
+VVLL+ LQ L V S+S+LW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3904 NVVLLNCLQHLHVASNSRLWQYCSILHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDTK 3963
Query 3927 ----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLK 3981
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L+
Sbjct 3964 CLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLE 4023
Query 3982 KSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLD 4041
K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLD
Sbjct 4024 KACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 4083
Query 4042 NDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQV 4101
N ALN+I++NA GCVPLN IP A L ++IPD + D YA ++W IQ V
Sbjct 4084 NQALNSILDNAVKGCVPLNAIPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQTV 4143
Query 4102 VDADSKIVQLSEISMDNSPNLAWPLIVTALRANS--AVKLQNNELSPVALRQMSCAAGTT 4159
DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4144 QDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSD 4199
Query 4160 QTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDT 4219
YYN GR V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4200 MNCNIPTQ--CYYNNGSSGRIVYAVLSDVDGLKYTKIIKDDGNCVV-LELDPPCKFSIQD 4256
Query 4220 PKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKA 4279
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VD K
Sbjct 4257 VKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKT 4316
Query 4280 YKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNP 4339
Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+
Sbjct 4317 YLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDV 4376
Query 4340 KGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSF 4399
G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D +F
Sbjct 4377 DGLCKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SGVAVQSKDL-NF 4433
Query 4400 LNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLI 4458
LNRV G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D+D N +
Sbjct 4434 LNRVRGTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRIDDDGNKL 4493
Query 4459 DSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMAD 4518
D +FVVKR Y E+T Y L K C VA+HDFF F IDG VPHI R+ L+KYTM D
Sbjct 4494 DKFFVVKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRKNLSKYTMLD 4553
Query 4519 LVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQAL 4578
L YALRHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG +AL
Sbjct 4554 LCYALRHFDCNDCSVLCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGPIFNRAL 4613
Query 4579 LKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILT 4638
L TV F D + G+VGVLTLDNQDL G WYDFGDFIQT PG GV V DSYYS +MP+LT
Sbjct 4614 LNTVSFADTLVKVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSYMMPMLT 4673
Query 4639 LTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRC 4698
+ L E V+ Y ++DL++YDFT+ +L+LF++YFKYW YHPN V+C +DRC
Sbjct 4674 MCHVLDCELFVN----DSYRQFDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVDCDNDRC 4729
Query 4699 ILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRL 4758
I+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RL
Sbjct 4730 IIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVDTHRYRL 4789
Query 4759 SFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSK 4818
S K+LL+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY+F SK
Sbjct 4790 SLKDLLLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFYEFVKSK 4849
Query 4819 GFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGG 4878
G FKEGS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGG
Sbjct 4850 GLFKEGSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGG 4909
Query 4879 CINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKY 4938
CI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+TQMNLKY
Sbjct 4910 CIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLTQMNLKY 4969
Query 4939 AISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVY 4998
AISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ +
Sbjct 4970 AISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRHLI 5029
Query 4999 SDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEM 5058
DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS RFYRLANECAQVLSE+
Sbjct 5030 KDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECAQVLSEI 5089
Query 5059 VMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHR 5118
VMCGG YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +RNLQ R
Sbjct 5090 VMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSIRNLQKR 5149
Query 5119 LYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVL 5178
LY +YR VD FVNE+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I F+ VL
Sbjct 5150 LYSNVYRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYASKGYIANISVFQQVL 5209
Query 5179 YYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDD 5238
YYQNNVFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGAGCFVDD
Sbjct 5210 YYQNNVFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGAGCFVDD 5269
Query 5239 IVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVM 5298
++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD YSV+
Sbjct 5270 LLKTDSVLLIERFVSLAIDAYPLVHHENEEYQKVFRVYLEYIKKLYNDLGNQILDSYSVI 5329
Query 5299 LTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHV 5358
L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV
Sbjct 5330 LSTCDGLKFTDESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHV 5389
Query 5359 ISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYK 5418
++T+HK VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG VFGLYK
Sbjct 5390 MATNHKYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGMVFGLYK 5449
Query 5419 NTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATV 5478
+C GS + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK SY AT+
Sbjct 5450 QSCTGSPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQSYASATI 5509
Query 5479 REVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGT 5538
+E++SDRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + + V YR T
Sbjct 5510 QEIVSDREIILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNGVYYRAT 5569
Query 5539 TTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKV 5596
TTYKL++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y ++ F +NVANYQ +
Sbjct 5570 TTYKLSIGDVFVLTSHSVANLSAPTLVPQENYASIRFSSVY---SVPLLFQTNVANYQHI 5626
Query 5597 GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5656
GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+R
Sbjct 5627 GMKRYCTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLNINDCTR 5686
Query 5657 IIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLR 5716
IIPA+ RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NAR++
Sbjct 5687 IIPAKVRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSVINARVK 5746
Query 5717 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5776
AKHYVYIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP EIV+TV
Sbjct 5747 AKHYVYIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPKEIVETV 5806
Query 5777 SALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFI 5836
SALVYDNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W AVFI
Sbjct 5807 SALVYDNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVWNSAVFI 5866
Query 5837 SPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGI 5896
SPYNSQN VA +ILG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK GI
Sbjct 5867 SPYNSQNYVAKRILGVQTQTVDSAQGSEYDYVIYSQTAETAHSINVNRFNVAITRAKKGI 5926
Query 5897 LCIMSDRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKVITGLHPTQAPTHLSVD 5955
C+MS+ L++ L F +L + + TL + T LFKDCSK G HP AP+ LSVD
Sbjct 5927 FCVMSNMQLFESLNFITLPLDKIQNQTLSRLHCTTNLFKDCSKNFLGYHPAHAPSFLSVD 5986
Query 5956 TKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGF 6014
K+K E L V + +TY RLIS+MGFK++ ++GY FIT++EAI+ VR W+GF
Sbjct 5987 DKYKVNEDLAVCLNICEPVLTYSRLISLMGFKLDLTLDGYSKFFITKDEAIKRVRGWVGF 6046
Query 6015 DVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHL 6074
DVEG HATR+ +GTN PLQ+GFSTGV+ V TG + F R AK PPGD FKHL
Sbjct 6047 DVEGAHATRDNIGTNFPLQIGFSTGVDFVVEATGLFAERDCYIFKRTVAKAPPGDNFKHL 6106
Query 6075 IPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCL 6134
IPLM KG W+VVRI+IVQMLSD L +LSD VVF+ W+ FELT ++YF K+G E C +
Sbjct 6107 IPLMSKGQKWDVVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGRELNCDV 6166
Query 6135 CDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHV 6194
C RATC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD+ C VH AHV
Sbjct 6167 CPNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNVHKGAHV 6226
Query 6195 ASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVL 6254
AS DAIMTRCLA+++CF K V+W +EYPII +E+ IN +CR +Q +++KAA+L +++ +
Sbjct 6227 ASSDAIMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLCNRYNLC 6286
Query 6255 HDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNV 6314
+DIGNPK I CV D E+KFYDA P +++LFY Y H D F DG+C+FWNCNV
Sbjct 6287 YDIGNPKGIACVK--DYEFKFYDASPV---VKSVKQLFYVYDVHKDNFKDGLCMFWNCNV 6341
Query 6315 DRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSD 6374
D+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +PFFYYSD
Sbjct 6342 DKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMPFFYYSD 6401
Query 6375 SPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLW 6434
+PC +DYVPL+SATCITRCNLGGAVC HA +Y YL++YN+ +AGF+ W
Sbjct 6402 TPCVYVDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEDYCKYLESYNVATTAGFTFW 6461
Query 6435 VYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVEL 6494
VYK FD YNLWNTFT LQSLENV +N+VN GH+DG+ GE+P +I+N+ V K++ VD +
Sbjct 6462 VYKTFDFYNLWNTFTMLQSLENVIYNLVNAGHYDGRIGELPCAIMNDKVVVKINNVDTVI 6521
Query 6495 FENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVC 6554
F+N T+LP N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +D+ ST GVC
Sbjct 6522 FKNNTSLPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVC 6581
Query 6555 SMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL 6614
TD+ L V FDGR +G ++ FR ARNGV I+ G + L GP++A L
Sbjct 6582 KYTDL------NFIENLNVLFDGRDNGALEAFRKARNGVFISTGKLSSLSMIKGPQRADL 6635
Query 6615 NGVTL--IGE-AVKTQFNYYKKVDGVVQQLPE---------------------------- 6643
NGV + +GE V+ F K D V+ +
Sbjct 6636 NGVIVDKVGELNVEFWFAMRKDGDDVIFSRADSLSPSHYWSPQGNLGGNCAGNASGNDAL 6695
Query 6644 ---TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGL 6700
T FTQSR L F+PRS +E DF+++ FI +Y LE YAF+HIVYG F++ +GGL
Sbjct 6696 ARFTIFTQSRVLSTFEPRSDLERDFIDMEDSLFIAKYGLEDYAFDHIVYGSFNYKVIGGL 6755
Query 6701 HLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKS 6760
HLLIGL +R K+S +++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS
Sbjct 6756 HLLIGLFRRLKKSNLVIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVVIVKS 6815
Query 6761 QDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLL 6820
+L+ VSKVV + +D+ + FMLWC D + TFYPK+Q++ W+PG +MP LYK + L
Sbjct 6816 LNLNCVSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATSDWKPGYSMPVLYKYLNVPL 6875
Query 6821 EKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGT 6880
E+ L NYG + LP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAPG+
Sbjct 6876 ERVSLWNYGKAINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSDKEVAPGS 6935
Query 6881 AVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKE 6940
AVLRQWLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP TKN+
Sbjct 6936 AVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPLTKNIGDY 6995
Query 6941 NDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSS 7000
N SK+GFFTYIC I+ KL+LGGSVAIKITE SWNADLYKLM +FA+WT F TNVNASSS
Sbjct 6996 NVSKDGFFTYICYLIRDKLSLGGSVAIKITEFSWNADLYKLMSYFAFWTVFCTNVNASSS 7055
Query 7001 EAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSL 7060
E FLIG NYLGK +IDG VMHANY+FWRN+ +YSLFDMSKF LKL GTAV++L
Sbjct 7056 EGFLIGINYLGKSCFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMSKFSLKLAGTAVVNL 7115
Query 7061 KEGQINDMILSLLSKGRLIIRENNRVVISSDVLVNN 7096
+ Q+ND++ SL+ +G+L++R+ + + D LVN
Sbjct 7116 RPDQLNDLVYSLIERGKLLVRDTRKEIFVGDSLVNT 7151
Score = 435 bits (1118), Expect = 6e-120, Method: Composition-based stats.
Identities = 196/1058 (19%), Positives = 367/1058 (35%), Gaps = 190/1058 (18%)
Query 13 HVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGVLPQLEQPYVFIK 72
HVQ +L +RD+ V + + V + +K GT L++ L + YV
Sbjct 71 HVQSNL----IRDIFVH---EDLHVVEVLTKTAVKSGTAILIKSPLHSLGGFPKGYVMGL 123
Query 73 RSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKN 126
+T +V+ L +G LG +VP G +P K + ++
Sbjct 124 FRSYKTK--RYVVHHLSMTTSTTNFGED--FLGWIVPF-GFMPSYVHKWFQFCRLYIEES 178
Query 127 GNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYV 186
+ D D E+ +P + + L+R+ G +V
Sbjct 179 DLIISNFKFDDYDFSVEDAYAEVHAEPKGKYSQK---------AYALLRQYRGIKPVLFV 229
Query 187 DNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSE 246
D C G +C++ +L + + + +AW+ R
Sbjct 230 DQYGCDYSGKLADCLQAY------GHYSLQDMRQKQSVW---LANCDFDIVVAWHVVRDS 280
Query 247 K-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGF 296
+ LQT I K D +G P + ++I+ + P + K
Sbjct 281 RFVMRLQTIATICGIKYVAQPTEDVVDGAVVIREPVHLLSADAIVLKL-PSLMKVMTHMD 339
Query 297 MGRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCE-FCGTENLTKE- 352
I+S+Y V +C + + C D+C W +G+ + C T + E
Sbjct 340 DFSIKSIYNV-DLCDCGFVMQYGYVDCFNDNCDFYGWVSGNMMDGFSCPLCCTVYDSSEV 398
Query 353 GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFS 412
A + G +P+N V+ + + G FG C++
Sbjct 399 KAQSSGVIPENPVL-----------------FTNSTDTVNPDSFNLYGYSVTPFGSCIY- 440
Query 413 YVGCHNKCAYWVPRASANIGC----NHTGVVGEGSEGLNDNLL-EILQKEKVNINIVGDF 467
+ W+P +++ ++GVVG S L+ L + V G+
Sbjct 441 WSPRPG---LWIPIIKSSVKSYDDLVYSGVVGCKSIVKETALITHALYLDYVQC-KCGNL 496
Query 468 KLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQK 527
+ N + G++ +Q++ + G++ +
Sbjct 497 EQNH-------------------ILGVNNSWCRQLLLNRGDYNM---------------- 521
Query 528 SILSPLYAFASEAARVVRSIFSRTLETAQNSVRV------------LQKAAITILDGISQ 575
+L + F R+ F+ + L ++ I +SQ
Sbjct 522 -LLKNIDLFVKR-----RADFACKFAVCGDGFVPFLLDGLIPRSYYLIQSGIFFTSLMSQ 575
Query 576 YSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW----------LTNIFGTVYEKL 624
+S + D + L + + V YI V +L +Q+ + N F T+ +
Sbjct 576 FSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDAS 635
Query 625 KPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNK 684
P WL + G+ F+ + A I AK + TFFKL+
Sbjct 636 APATGWLLYQLLNGL-----------FVVSQANFNFVALIPDYAKILVNKFYTFFKLL-- 682
Query 685 FLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSREETGLLMPLKA-PKE 738
L ++ LK +N +G F S GL G ++P A ++
Sbjct 683 -LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI---------PGFVLPCNAQEQQ 732
Query 739 IIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTPVCINGLMLLEIKDT 796
I F EG + E V+++ ++ ++ S E + P +CI M +
Sbjct 733 IYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGD 785
Query 797 EKYCALAPNMMV-TNNTFTLKGGAPTKVTFGDDTVI-EVQGYKSVNITFELDERIDKVLN 854
+ + + + + + A KV F + V+ E+ +V + F+LD D +L
Sbjct 786 KFFPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILG 845
Query 855 EKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDES 911
+ CS + VE G V++F VV DA+ L + + + L++ + YLFDE+
Sbjct 846 KVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKDHPVVGYQVRAFLNKLNENVVYLFDEA 905
Query 912 GEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQ 970
G+ +AS MYC+F D ED + E+ + + ++D +
Sbjct 906 GDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDDED---VVTGDNDDEDVVT 962
Query 971 PEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEV 1008
+ + E+ D+ + V D +++ T +V
Sbjct 963 GDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDV 1000
Score = 197 bits (501), Expect = 4e-48, Method: Composition-based stats.
Identities = 64/254 (25%), Positives = 106/254 (42%), Gaps = 17/254 (7%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A E+ +
Sbjct 1328 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1387
Query 1092 ATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLL 1149
+ G +VG V +G L K L++VGP+ + LL AY++ N ++ L+ L+
Sbjct 1388 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1447
Query 1150 SAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPK 1208
SAGIF SL + V V L +K +D + + K + ++
Sbjct 1448 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDIIQKCQITSVVGTKALAVRLTANVG 1507
Query 1209 EEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDI------NGN 1262
+K K + C ++ ++E L ++ L D+
Sbjct 1508 RVIKFETDAYKLFLSGD--------DCFVSNSSVIQEVLLLRHDIQLNNDVRDYLLSKMT 1559
Query 1263 LHPDSATLVSDIDI 1276
P L++ D+
Sbjct 1560 SLPKDWRLINKFDV 1573
Score = 54.3 bits (129), Expect = 7e-05, Method: Composition-based stats.
Identities = 42/200 (21%), Positives = 73/200 (37%), Gaps = 21/200 (11%)
Query 1597 TYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKW 1656
D D + + + ++ Y L V D ++S + +
Sbjct 1061 VTGDNDDQIVVTGDDVDDIESVYDFDTYKALLV-------FNDVYNDALFVSYGSSVETE 1113
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1114 TYFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLT 1173
Query 1717 YCNKTVGEL--GDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
K + G V + + ++ N C CG L G++AV + G +
Sbjct 1174 TIPKAIVLPQGGYVADFAYWFLNQFDI---NAYANWCCLKCGF-SFDLNGLDAVFFYGDI 1229
Query 1775 SYEQFKKGVQIPCTCGKQAT 1794
V C CG T
Sbjct 1230 --------VSHVCKCGHNMT 1241
>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132
Score = 7722 bits (20035), Expect = 0.0, Method: Composition-based stats.
Identities = 2743/5676 (48%), Positives = 3667/5676 (65%), Gaps = 178/5676 (3%)
Query 1512 KDWSYSGQ-STQLGIEFLKR----GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLRE 1564
KDW + G++ +K + + DG T + + LL+
Sbjct 1543 KDWRLINKFDVINGVKTVKYFECPNSIYICSQGKDFGYVCDGSFYKATVNQVCVLLA--- 1599
Query 1565 VRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPND 1624
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1600 -KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENL 1658
Query 1625 DTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQ 1684
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1659 SLADISAVQSSFGFDQQQLLAYYNFL-TVCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQ 1717
Query 1685 QIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSC 1744
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1718 HINLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGA 1777
Query 1745 KRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF
Sbjct 1778 ICELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPF 1835
Query 1805 VMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPIT 1864
++ S P +L A+ + G GHY H+ D + K + G +T
Sbjct 1836 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1893
Query 1865 DVFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP-- 1921
D Y +N + T T Y LD V +P L YY + Y+T +PI +P+
Sbjct 1894 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKV 1952
Query 1922 NASFDNFKFVCDNIKFADDLNQLTGYKKP-ASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
+ + NFK V +I LN G+ E KVT +P GDVV Y +
Sbjct 1953 DGVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYF 2010
Query 1981 KGAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDN 2038
KG + KP++W H + N TY ++ ++ N + VL D+
Sbjct 2011 KGCETFGKPVIWFCHDEASLNSLTY----------FNKPSFKSENRYSVLSV------DS 2054
Query 2039 LACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMA 2097
++ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2055 VSEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWD 2114
Query 2098 AYVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT 2154
Y+ + NELSR++ T+ +G+ + ++P D + N+ +
Sbjct 2115 MYLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRDD---NQTLLVPK 2170
Query 2155 NIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEAS 2214
R + ++ + F + L FT T IA ++ L+ +
Sbjct 2171 IFKARAIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNA 2224
Query 2215 FNYLKSPNFSKLIN-----IIIWF--LLLSVCLGSL---------IYSTAALGVLMSNLG 2258
F + F K + WF L ++V I+ + + + G
Sbjct 2225 FQTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFG 2284
Query 2259 MPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKW-- 2316
+ + C Y + + T+ +C GS C +C SG D LDTY +++ +Q +
Sbjct 2285 LVTICDFYSKLGVGFTS----HFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFD 2340
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2341 YVSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2400
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2401 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2460
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2461 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2520
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + + + ++
Sbjct 2521 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVESDA--DRANF 2578
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2579 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQIMFDVYVDTFMSHFDVDRKSFNNFVN 2638
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2639 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2698
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK NI+ IW + F L+ L+ +++ A
Sbjct 2699 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKVANISCIWFIDAFNQLTADLQHKLKKAC 2758
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L ++L+ + + + P
Sbjct 2759 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPT 2815
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ G Y N C
Sbjct 2816 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDC 2875
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2876 PIVVAVMDEDIGSTMFNVPTKVLRY-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2934
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2935 GCVLSSLCTMFKRGDGTPHPYCYTDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 2994
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 2995 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDFFDLFYQF 3054
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3055 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFL 3114
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3115 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3174
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N S STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3175 NHVLWLFS--YCRKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3230
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3231 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3290
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R + +F
Sbjct 3291 VSPTSKIEPCLVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDF 3350
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3351 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAF 3410
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3411 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFNGNFYGPYR 3470
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM + + D
Sbjct 3471 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADL 3530
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3531 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3587
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + + ++ +F M+ V
Sbjct 3588 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYINTH-MIGVTLCVLCFVSFMMLLV 3646
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3647 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYEVFYGCIL 3706
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3707 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTWTT 3764
Query 3749 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 3808
+ +A+ IV + +F ++ I+L Y F+GY +CY+G F LLN FR+ +
Sbjct 3765 ILSLAIAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPM 3823
Query 3809 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCT 3868
GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3824 GVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCA 3883
Query 3869 SVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD-- 3926
+VVLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL S AVD
Sbjct 3884 NVVLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFSNPAAVDTK 3943
Query 3927 ----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLK 3981
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L+
Sbjct 3944 CLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLE 4003
Query 3982 KSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLD 4041
K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLD
Sbjct 4004 KACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 4063
Query 4042 NDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQV 4101
N ALN+I++NA GCVPL+ IP A L ++IPD + D TYA ++W IQ V
Sbjct 4064 NQALNSILDNAVKGCVPLSAIPALAANTLTIIIPDKQVFDKVVDNVYVTYAGSVWHIQTV 4123
Query 4102 VDADSKIVQLSEISMDNSPNLAWPLIVTALRANS--AVKLQNNELSPVALRQMSCAAGTT 4159
DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4124 QDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSD 4179
Query 4160 QTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDT 4219
YYN GR V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4180 INCNIPTQ--CYYNNVSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFSIQD 4236
Query 4220 PKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKA 4279
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VD K
Sbjct 4237 VKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKT 4296
Query 4280 YKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNP 4339
Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+
Sbjct 4297 YLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDV 4356
Query 4340 KGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSF 4399
G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D +F
Sbjct 4357 DGICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SSVAVQSKDL-NF 4413
Query 4400 LNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLI 4458
LNRV G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D+D N +
Sbjct 4414 LNRVRGTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRIDDDGNKL 4473
Query 4459 DSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMAD 4518
D +FVVKR Y E+T Y L K C VA+HDFF F IDG VPHI R+ L+KYTM D
Sbjct 4474 DKFFVVKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRRNLSKYTMLD 4533
Query 4519 LVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQAL 4578
L YALRHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG +AL
Sbjct 4534 LCYALRHFDRNDCSILCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGPIFNRAL 4593
Query 4579 LKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILT 4638
L TV F D + G+VGVLTLDNQDL G WYDFGDFIQT PG GV V DSYYS +MP+LT
Sbjct 4594 LNTVIFADTLVEVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSYMMPMLT 4653
Query 4639 LTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRC 4698
+ L E V+ Y ++DL++YDFT+ +L+LF++YFKYW YHPN V+C +DRC
Sbjct 4654 MCHVLDCELFVN----DSYRQFDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVDCDNDRC 4709
Query 4699 ILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRL 4758
I+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RL
Sbjct 4710 IIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVDTHRYRL 4769
Query 4759 SFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSK 4818
S K+LL+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY+F SK
Sbjct 4770 SLKDLLLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFYEFVKSK 4829
Query 4819 GFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGG 4878
G FKEGS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGG
Sbjct 4830 GLFKEGSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGG 4889
Query 4879 CINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKY 4938
CI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+TQMNLKY
Sbjct 4890 CIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLTQMNLKY 4949
Query 4939 AISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVY 4998
AISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ +
Sbjct 4950 AISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRHLI 5009
Query 4999 SDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEM 5058
DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS RFYRLANECAQVLSE+
Sbjct 5010 KDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECAQVLSEI 5069
Query 5059 VMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHR 5118
VMCGG YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +RNLQ R
Sbjct 5070 VMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSIRNLQKR 5129
Query 5119 LYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVL 5178
LY +YR VD FVNE+Y +L KHFSMMILSDD VVC+NS YA++G +A+I F+ VL
Sbjct 5130 LYSNVYRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYANKGYIANISAFQQVL 5189
Query 5179 YYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDD 5238
YYQNNVFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGAGCFVDD
Sbjct 5190 YYQNNVFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGAGCFVDD 5249
Query 5239 IVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVM 5298
++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD YSV+
Sbjct 5250 LLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNDLGTQILDSYSVI 5309
Query 5299 LTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHV 5358
L+ + ++ E FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV
Sbjct 5310 LSTCDGLKFTEESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHV 5369
Query 5359 ISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYK 5418
++T+HK VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG VFGLYK
Sbjct 5370 MATNHKYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGMVFGLYK 5429
Query 5419 NTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATV 5478
+C GS + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK SY AT+
Sbjct 5430 QSCTGSPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQSYASATI 5489
Query 5479 REVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGT 5538
+E++SDRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + + V YR T
Sbjct 5490 QEIVSDREVILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNGVYYRAT 5549
Query 5539 TTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKV 5596
TTYKL++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y ++ F +NVANYQ +
Sbjct 5550 TTYKLSIGDVFVLTSHSVASLSAPTLVPQENYASIRFSSVY---SVPLVFQNNVANYQHI 5606
Query 5597 GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5656
GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+R
Sbjct 5607 GMKRYCTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLNINDCTR 5666
Query 5657 IIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLR 5716
IIPA+ RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NAR++
Sbjct 5667 IIPAKVRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSVINARIK 5726
Query 5717 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5776
AKHYVYIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP EIV+TV
Sbjct 5727 AKHYVYIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPKEIVETV 5786
Query 5777 SALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFI 5836
SALVYDNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W AVFI
Sbjct 5787 SALVYDNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVWNSAVFI 5846
Query 5837 SPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGI 5896
SPYNSQN VA ++LG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK GI
Sbjct 5847 SPYNSQNYVAKRVLGVQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKGI 5906
Query 5897 LCIMSDRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKVITGLHPTQAPTHLSVD 5955
C+MS+ L++ L F +L + + TL + T LFKDCSK G HP AP+ L+VD
Sbjct 5907 FCVMSNMQLFESLNFITLPLDKIQNQTLPRLHCTTNLFKDCSKSCLGYHPAHAPSFLAVD 5966
Query 5956 TKFKTEG-LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGF 6014
K+K L V++ +TY RLIS+MGFK++ ++GY +FIT++EAI+ VR W+GF
Sbjct 5967 DKYKVNENLAVNLNICEPVLTYSRLISLMGFKLDLTLDGYSKLFITKDEAIKRVRGWVGF 6026
Query 6015 DVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHL 6074
DVEG HATRE +GTN PLQ+GFSTGV+ V TG + F + AK PPG++FKHL
Sbjct 6027 DVEGAHATRENIGTNFPLQIGFSTGVDFVVEATGLFAERDCYTFKKTVAKAPPGEKFKHL 6086
Query 6075 IPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCL 6134
IPLM KG W++VRI+IVQMLSD L +LSD VVF+ W+ FELT ++YF K+G E C +
Sbjct 6087 IPLMSKGQKWDIVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGRELNCNV 6146
Query 6135 CDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHV 6194
C RATC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD+ C VH AHV
Sbjct 6147 CSNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNVHKGAHV 6206
Query 6195 ASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVL 6254
AS DAIMTRCLA+++CF K V+W +EYPII +E+ IN +CR +Q +++KAA+L +++ +
Sbjct 6207 ASADAIMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLCNRYNLC 6266
Query 6255 HDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNV 6314
+DIGNPK + CV D E+KFYDA P A +++LFY Y H D F DG+C+FWNCNV
Sbjct 6267 YDIGNPKGLACVK--DYEFKFYDAFPV---AKSVKQLFYVYDVHKDNFKDGLCMFWNCNV 6321
Query 6315 DRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSD 6374
D+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +PFFYYSD
Sbjct 6322 DKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMPFFYYSD 6381
Query 6375 SPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLW 6434
+PC +DYVPL+SATCITRCNLGGAVC HA EY YL++YN++ +AGF+ W
Sbjct 6382 TPCVYVDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEEYCNYLESYNIVTTAGFTFW 6441
Query 6435 VYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVEL 6494
VYK FD YNLWNTFT LQSLENV +N+VN GH+DG+ GE+P +I+N+ V K++ VD +
Sbjct 6442 VYKTFDFYNLWNTFTTLQSLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKINNVDTVI 6501
Query 6495 FENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVC 6554
F+N T+ P N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +D+ ST GVC
Sbjct 6502 FKNNTSFPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVC 6561
Query 6555 SMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL 6614
TD+ L + FDGR G ++ FR ARNGV I+ + L GP++A L
Sbjct 6562 KYTDLK------FIENLNILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKGPQRADL 6615
Query 6615 NGVTL--IGE-AVKTQFNYYKKVDGVVQQLPE---------------------------- 6643
NGV + +GE V+ F K D V+ +
Sbjct 6616 NGVIVDKVGELKVEFWFAMRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGNVIGNDAL 6675
Query 6644 ---TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGL 6700
T FTQSR L F+PRS +E DF+++ + FI +Y LE YAF+HIVYG F+H +GGL
Sbjct 6676 TRFTIFTQSRVLSSFEPRSDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFNHKVIGGL 6735
Query 6701 HLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKS 6760
HLLIGL +R K+S +++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS
Sbjct 6736 HLLIGLFRRLKKSNLLIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVSIVKS 6795
Query 6761 QDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLL 6820
+LS VSKVV + +D+ + FMLWC D + TFYPK+Q++ W+PG +MP LYK + L
Sbjct 6796 LNLSCVSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATNDWKPGYSMPVLYKYLNVPL 6855
Query 6821 EKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGT 6880
E+ L NYG LP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAPG+
Sbjct 6856 ERVSLWNYGKPINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSDKEVAPGS 6915
Query 6881 AVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKE 6940
AVLRQWLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP TKN+
Sbjct 6916 AVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPLTKNIGDY 6975
Query 6941 NDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSS 7000
N SK+GFFTYIC I+ KL+LGGSVAIKITE SWNADLYKLM FA+WT F TNVNASSS
Sbjct 6976 NVSKDGFFTYICHLIRDKLSLGGSVAIKITEFSWNADLYKLMSCFAFWTVFCTNVNASSS 7035
Query 7001 EAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSL 7060
E FLIG NYLGK +IDG VMHANY+FWRN+ +YSLFDM+KF LKL GTAV++L
Sbjct 7036 EGFLIGINYLGKSSFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMTKFSLKLAGTAVVNL 7095
Query 7061 KEGQINDMILSLLSKGRLIIRENNRVVISSDVLVNN 7096
+ Q+ND++ SL+ +G+L++R+ + + D LVN
Sbjct 7096 RPDQLNDLVYSLIERGKLLVRDTRKEIFVGDSLVNT 7131
Score = 432 bits (1111), Expect = 4e-119, Method: Composition-based stats.
Identities = 203/1117 (18%), Positives = 379/1117 (34%), Gaps = 202/1117 (18%)
Query 13 HVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGVLPQLEQPYVFIK 72
HVQ +L +RD+ V + + V + +K GT L++ L + YV
Sbjct 71 HVQSNL----IRDIFVH---EDLHVVEVLTKTAVKSGTAILIKSPLHSLGGFPKGYVMGL 123
Query 73 RSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKN 126
+T +V+ L +G G +VP G +P K + ++
Sbjct 124 FRSYKTK--RYVVHHLSMTTSTTNFGED--FFGWIVPF-GFMPSYVHKWFQFCRLYIEES 178
Query 127 GNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYV 186
+ D E+ +P + + L+R+ G +V
Sbjct 179 DLIISNFKFDDYDFSVEAAYAEVHAEPKGKYSQK---------AYALLRQYRGIKPVLFV 229
Query 187 DNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSE 246
D C G +C++ +L + + + +AW+ R
Sbjct 230 DQYGCDYSGKLADCLQAY------GHYSLQDMRQKQSVW---LANCDFDIVVAWHVVRDS 280
Query 247 K-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGF 296
+ LQT I K D +G+ P + ++I+ + P + K
Sbjct 281 RFVMRLQTIATICGIKYVAQPTEDVVDGDVVIREPVHLLSADAIVLKL-PSLMKVMTHMD 339
Query 297 MGRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCE-FCGTENLTKE- 352
I+S+Y V +C + + C D+C W +G+ + C T + E
Sbjct 340 DFSIKSIYNV-DLCDCGFVMQYGYVDCFNDNCDFYGWVSGNMMDGFSCPLCCTVYDSSEV 398
Query 353 GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFS 412
A + G +P+N V+ + + G FG C++
Sbjct 399 KAQSSGVIPENPVL-----------------FTNSTDTVNPDSFNLYGYSVTPFGSCIY- 440
Query 413 YVGCHNKCAYWVPRASANIGC----NHTGVVGEGSEGLNDNLL-EILQKEKVNINIVGDF 467
+ W+P +++ ++GVVG S L+ L + V G+
Sbjct 441 WSPRPG---LWIPIIKSSVKSYDDLVYSGVVGCKSIVKETALITHALYLDYVQC-KCGNL 496
Query 468 KLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQK 527
+ N + G++ +Q++ + G++ +
Sbjct 497 EQNH-------------------ILGVNNSWCRQLLLNRGDYNM---------------- 521
Query 528 SILSPLYAFASEAARVVRSIFSRTLETAQNSVRV------------LQKAAITILDGISQ 575
+L + F R+ F+ + L ++ I +SQ
Sbjct 522 -LLKNIDLFVKR-----RADFACKFAVCGDGFVPFLLDGLIPRSYYLIQSGIFFTSLMSQ 575
Query 576 YSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW----------LTNIFGTVYEKL 624
+S + D + L + + V YI V +L +Q+ + N F T+ +
Sbjct 576 FSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDAS 635
Query 625 KPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNK 684
P WL + G F+ + A I AK + TFFKL+
Sbjct 636 APATGWLLYQLLNGF-----------FVVSQANLNFVALIPDYAKILVNKFYTFFKLL-- 682
Query 685 FLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSREETGLLMPLKA-PKE 738
L ++ LK +N +G F S GL G ++P A ++
Sbjct 683 -LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI---------PGFVLPCNAQEQQ 732
Query 739 IIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTPVCINGLMLLEIKDT 796
I F EG + E V+++ ++ ++ S E + P +CI M +
Sbjct 733 IYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGD 785
Query 797 EKYCALAPNMMV-TNNTFTLKGGAPTKVTFGDDTVI-EVQGYKSVNITFELDERIDKVLN 854
+ + + + + + A KV F + V+ E+ +V + F+LD D +L
Sbjct 786 KFFPIVMNDKNICLLDHAWRFPCAGRKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILG 845
Query 855 EKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDES 911
+ CS + VE G V++F VV DA+ L E + + L++ + YLFDE+
Sbjct 846 KVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQVRAFLNKLNENVVYLFDEA 905
Query 912 GEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTEDD------YQGKPLEFGA 964
G+ +AS MYC+F D ED + E+ + + ++D +
Sbjct 906 GDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDDEDVVTGDNDDEDVVTGDN 965
Query 965 TSAALQPEEEQEEDWL---DDDSQQTVGQQD------GSEDNQTTTIQTIVEVQPQLEME 1015
+ + +ED + +DD G D G D++ +
Sbjct 966 DDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDN 1025
Query 1016 LTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKV 1052
V T + N D+ + D V++ + +
Sbjct 1026 NDEDVVTGDNNDEESVTGDNDDQIVVTGDDVDDIESI 1062
Score = 197 bits (501), Expect = 4e-48, Method: Composition-based stats.
Identities = 64/254 (25%), Positives = 106/254 (42%), Gaps = 17/254 (7%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A E+ +
Sbjct 1308 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1367
Query 1092 ATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLL 1149
+ G +VG V +G L K L++VGP+ + LL AY++ N ++ L+ L+
Sbjct 1368 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1427
Query 1150 SAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPK 1208
SAGIF SL + V V L +K +D + + K + ++
Sbjct 1428 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDIIQKCQITSVVGTKALAVRLTANVG 1487
Query 1209 EEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDI------NGN 1262
+K K + C ++ ++E L ++ L D+
Sbjct 1488 RVIKFETDAYKLFLSGD--------DCFVSNSSVIQEVLLLRHDIQLNNDVRDYLLSKMT 1539
Query 1263 LHPDSATLVSDIDI 1276
P L++ D+
Sbjct 1540 SLPKDWRLINKFDV 1553
Score = 55.1 bits (131), Expect = 4e-05, Method: Composition-based stats.
Identities = 42/201 (21%), Positives = 73/201 (36%), Gaps = 21/201 (10%)
Query 1596 PTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKK 1655
D D + + + ++ Y L V D ++S + +
Sbjct 1040 SVTGDNDDQIVVTGDDVDDIESIYDFDTYKALLV-------FNDVYNDALFVSYGSSVET 1092
Query 1656 WKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALIL 1715
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1093 ETYFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLL 1152
Query 1716 AYCNKTVGEL--GDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGT 1773
K + G V + + ++ N C CG L G++AV + G
Sbjct 1153 TTIPKAIVLPQGGYVADFAYWFLNQFDI---NAYANWCCLKCGF-SFDLNGLDAVFFYGD 1208
Query 1774 LSYEQFKKGVQIPCTCGKQAT 1794
+ V C CG T
Sbjct 1209 I--------VSHVCKCGHNMT 1221
>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182
Score = 7714 bits (20016), Expect = 0.0, Method: Composition-based stats.
Identities = 2745/5676 (48%), Positives = 3668/5676 (65%), Gaps = 178/5676 (3%)
Query 1512 KDWSYSGQ-STQLGIEFLKR----GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLRE 1564
KDW + G++ +K + + DG T + + LL+
Sbjct 1593 KDWRLINKFDVINGVKTVKYFECPNSIYICSQGKDFGYVCDGSFYKATVNQVCVLLA--- 1649
Query 1565 VRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPND 1624
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1650 -KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENL 1708
Query 1625 DTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQ 1684
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1709 SLADISAVQSSFGFDQQQLLAYYNFL-TVCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQ 1767
Query 1685 QIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSC 1744
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1768 HINLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGA 1827
Query 1745 KRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF
Sbjct 1828 ICELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPF 1885
Query 1805 VMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPIT 1864
++ S P +L A+ + G GHY H+ D + K + G +T
Sbjct 1886 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1943
Query 1865 DVFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP-- 1921
D Y +N + T T Y LD V +P L YY + Y+T +PI +P+
Sbjct 1944 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKV 2002
Query 1922 NASFDNFKFVCDNIKFADDLNQLTGYKKP-ASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
+ + NFK V +I LN G+ E KVT +P GDVV Y +
Sbjct 2003 DGVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYF 2060
Query 1981 KGAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDN 2038
KG + KP++W H + N TY ++ ++ N + VL D+
Sbjct 2061 KGCETFGKPVIWFCHDEASLNSLTY----------FNKPSFKSENRYSVLSV------DS 2104
Query 2039 LACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMA 2097
++ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2105 VSEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWD 2164
Query 2098 AYVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT 2154
Y+ + NELSR++ T+ +G+ + ++P D + N+ +
Sbjct 2165 MYLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRDD---NQTLLVPK 2220
Query 2155 NIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEAS 2214
R + ++ + F + L FT T IA ++ L+ +
Sbjct 2221 IFKARAIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNA 2274
Query 2215 FNYLKSPNFSKLIN-----IIIWF--LLLSVCLGSL---------IYSTAALGVLMSNLG 2258
F + F K + WF L ++V I+ + + + G
Sbjct 2275 FQTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFG 2334
Query 2259 MPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKW-- 2316
+ + C Y + + T+ +C GS C +C SG D LDTY +++ +Q +
Sbjct 2335 LVTICDFYSKLGVGFTS----HFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFD 2390
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2391 YVSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2450
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2451 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2510
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2511 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2570
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + + + ++
Sbjct 2571 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVESDA--DRANF 2628
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2629 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVN 2688
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2689 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2748
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK+ NI+ IW + F L+ L+ +++ A
Sbjct 2749 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDAFNQLTADLQHKLKKAC 2808
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L V+L+ + + + P
Sbjct 2809 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFVSLICFI---LLWALLPT 2865
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ G Y N C
Sbjct 2866 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDC 2925
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2926 PIVVAVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2984
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2985 GCVLSSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 3044
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 3045 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQF 3104
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3105 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVVVWCINFL 3164
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3165 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3224
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N S STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3225 NHVLWLFS--YCRKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3280
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3281 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3340
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC+S +M P+Y LL R + +F
Sbjct 3341 VSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICSSSNMNEPDYSALLCRVTLGDF 3400
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3401 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGNVKPGETFTVLAAYNGRPQGAF 3460
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3461 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYR 3520
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ + DFN+ AM + + D
Sbjct 3521 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSTEDFNVWAMANGFSQVKADL 3580
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3581 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3637
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + + ++ +F M+ V
Sbjct 3638 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYINTH-MIGVTLCVLCFVSFMMLLV 3696
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3697 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSYFVPAVNFTYVYEVFYGCIL 3756
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3757 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTWTT 3814
Query 3749 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 3808
+ +A+ IV + +F ++ I+L Y F+GY +CY+G F LLN FR+ +
Sbjct 3815 ILSLAIAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPM 3873
Query 3809 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCT 3868
GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3874 GVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCA 3933
Query 3869 SVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD-- 3926
+VVLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3934 NVVLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDTK 3993
Query 3927 ----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLK 3981
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L+
Sbjct 3994 CLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLE 4053
Query 3982 KSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLD 4041
K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLD
Sbjct 4054 KACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 4113
Query 4042 NDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQV 4101
N ALN+I++NA GCVPL+ IP A L +VIPD + D TYA ++W IQ V
Sbjct 4114 NQALNSILDNAVKGCVPLSAIPALAANTLTIVIPDKQVFDKVVDNVYVTYAGSVWHIQTV 4173
Query 4102 VDADSKIVQLSEISMDNSPNLAWPLIVTALRANS--AVKLQNNELSPVALRQMSCAAGTT 4159
DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4174 QDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSD 4229
Query 4160 QTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDT 4219
YYN GR V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4230 MNCNIPTQ--CYYNNGSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFSIQD 4286
Query 4220 PKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKA 4279
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VD K
Sbjct 4287 VKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKT 4346
Query 4280 YKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNP 4339
Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+
Sbjct 4347 YLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDV 4406
Query 4340 KGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSF 4399
G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D +F
Sbjct 4407 DGICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SSVAVQSKDL-NF 4463
Query 4400 LNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLI 4458
LNRV G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D+D N +
Sbjct 4464 LNRVRGTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRIDDDGNKL 4523
Query 4459 DSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMAD 4518
D +FVVKR Y E+T Y L K C VA+HDFF F IDG VPHI R+ L+KYTM D
Sbjct 4524 DKFFVVKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRRNLSKYTMLD 4583
Query 4519 LVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQAL 4578
L YALRHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG +AL
Sbjct 4584 LCYALRHFDRNDCSILCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGPIFNRAL 4643
Query 4579 LKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILT 4638
L TV F D + G+VGVLTLDNQDL G WYDFGDFIQT PG GV V DSYYS +MP+LT
Sbjct 4644 LNTVIFADTLVEVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSYMMPMLT 4703
Query 4639 LTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRC 4698
+ L E V+ Y ++DL++YDFT+ +L+LF++YFKYW YHPN V+C +DRC
Sbjct 4704 MCHVLDCELFVN----DSYRQFDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVDCDNDRC 4759
Query 4699 ILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRL 4758
I+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RL
Sbjct 4760 IIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVDTHRYRL 4819
Query 4759 SFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSK 4818
S K+LL+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY+F SK
Sbjct 4820 SLKDLLLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFYEFVKSK 4879
Query 4819 GFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGG 4878
G FKEGS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGG
Sbjct 4880 GLFKEGSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGG 4939
Query 4879 CINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKY 4938
CI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+TQMNLKY
Sbjct 4940 CIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLTQMNLKY 4999
Query 4939 AISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVY 4998
AISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ +
Sbjct 5000 AISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRHLI 5059
Query 4999 SDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEM 5058
DV+NP LMGWDYPKCDRAMPN+LRI++SLVLARKH CCS RFYRLANECAQVLSE+
Sbjct 5060 KDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECAQVLSEI 5119
Query 5059 VMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHR 5118
VMCGG YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +RNLQ R
Sbjct 5120 VMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSIRNLQKR 5179
Query 5119 LYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVL 5178
LY +YR VD FVNE+Y +L KHFSMMILSDD VVC+NS YAS+G +A+I F+ VL
Sbjct 5180 LYSNVYRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYASKGYIANISVFQQVL 5239
Query 5179 YYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDD 5238
YYQNNVFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGAGCFVDD
Sbjct 5240 YYQNNVFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGAGCFVDD 5299
Query 5239 IVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVM 5298
++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD YSV+
Sbjct 5300 LLKTDSVLLIERFVSLAIDAYPLVHHENEEYQKVFRVYLEYIKKLYNDLGTQILDSYSVI 5359
Query 5299 LTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHV 5358
L+ + ++ E FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV
Sbjct 5360 LSTCDGLKFTEESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHV 5419
Query 5359 ISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYK 5418
++T+HK VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG VFGLYK
Sbjct 5420 MATNHKYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGMVFGLYK 5479
Query 5419 NTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATV 5478
+C GS + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK SY AT+
Sbjct 5480 QSCTGSPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQSYASATI 5539
Query 5479 REVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGT 5538
+E++SDRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + + V YR T
Sbjct 5540 QEIVSDREVILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNGVYYRAT 5599
Query 5539 TTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKV 5596
TTYKL++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y ++ F +NVANYQ +
Sbjct 5600 TTYKLSIGDVFVLTSHSVASLSAPTLVPQENYASIRFSSVY---SVPLVFQNNVANYQHI 5656
Query 5597 GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5656
GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+R
Sbjct 5657 GMKRYCTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLNINDCTR 5716
Query 5657 IIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLR 5716
IIPA+ RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NAR++
Sbjct 5717 IIPAKVRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSVINARIK 5776
Query 5717 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5776
AKHYVYIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP EIV+TV
Sbjct 5777 AKHYVYIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPKEIVETV 5836
Query 5777 SALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFI 5836
SALVYDNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W AVFI
Sbjct 5837 SALVYDNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVWNSAVFI 5896
Query 5837 SPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGI 5896
SPYNSQN VA ++LG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK GI
Sbjct 5897 SPYNSQNYVAKRVLGVQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKGI 5956
Query 5897 LCIMSDRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKVITGLHPTQAPTHLSVD 5955
C+MS+ L++ L F +L + + TL + T LFKDCSK G HP AP+ L+VD
Sbjct 5957 FCVMSNMQLFESLNFITLPLDKIQNQTLPRLHCTTNLFKDCSKSCLGYHPAHAPSFLAVD 6016
Query 5956 TKFKTEG-LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGF 6014
K+K L V++ +TY RLIS+MGFK++ ++GY +FIT++EAI+ VR W+GF
Sbjct 6017 DKYKVNENLAVNLNICEPVLTYSRLISLMGFKLDLTLDGYSKLFITKDEAIKRVRGWVGF 6076
Query 6015 DVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHL 6074
DVEG HATRE +GTN PLQ+GFSTGV+ V TG + F + AK PPG++FKHL
Sbjct 6077 DVEGAHATRENIGTNFPLQIGFSTGVDFVVEATGLFAERDCYTFKKTVAKAPPGEKFKHL 6136
Query 6075 IPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCL 6134
IPLM KG W++VRI+IVQMLSD L +LSD VVF+ W+ FELT ++YF K+G E C +
Sbjct 6137 IPLMSKGQKWDIVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGRELNCNV 6196
Query 6135 CDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHV 6194
C RATC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD+ C VH AHV
Sbjct 6197 CSNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNVHKGAHV 6256
Query 6195 ASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVL 6254
AS DAIMTRCLA+++CF K V+W +EYPII +E+ IN +CR +Q +++KAA+L +++ +
Sbjct 6257 ASADAIMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLCNRYNLC 6316
Query 6255 HDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNV 6314
+DIGNPK + CV D E+KFYDA P A +++LFY Y H D F DG+C+FWNCNV
Sbjct 6317 YDIGNPKGLACVK--DYEFKFYDAFPV---AKSVKQLFYVYDVHKDNFKDGLCMFWNCNV 6371
Query 6315 DRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSD 6374
D+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +PFFYYSD
Sbjct 6372 DKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMPFFYYSD 6431
Query 6375 SPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLW 6434
+PC +DYVPL+SATCITRCNLGGAVC HA EY YL++YN++ +AGF+ W
Sbjct 6432 TPCVYVDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEEYCNYLESYNIVTTAGFTFW 6491
Query 6435 VYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVEL 6494
VYK FD YNLWNTFT LQSLENV +N+VN GH+DG+ GE+P +I+N+ V K++ VD +
Sbjct 6492 VYKNFDFYNLWNTFTTLQSLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKINNVDTVI 6551
Query 6495 FENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVC 6554
F+N T+ P N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +D+ ST GVC
Sbjct 6552 FKNNTSFPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVC 6611
Query 6555 SMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL 6614
TD+ L + FDGR G ++ FR ARNGV I+ + L GP++A L
Sbjct 6612 KYTDLK------FIENLNILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKGPQRADL 6665
Query 6615 NGVTL--IGE-AVKTQFNYYKKVDGVVQQLPE---------------------------- 6643
NGV + +GE V+ F K D V+ +
Sbjct 6666 NGVIVDKVGELKVEFWFAMRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGNVIGNDAL 6725
Query 6644 ---TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGL 6700
T FTQSR L F+PRS +E DF+++ + FI +Y LE YAF+HIVYG F+H +GGL
Sbjct 6726 TRFTIFTQSRVLSSFEPRSDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFNHKVIGGL 6785
Query 6701 HLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKS 6760
HLLIGL +R K+S +++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS
Sbjct 6786 HLLIGLFRRKKKSNLLIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVSIVKS 6845
Query 6761 QDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLL 6820
+LS VSKVV + +D+ + FMLWC D + TFYPK+Q++ W+PG +MP LYK + L
Sbjct 6846 LNLSCVSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATNDWKPGYSMPVLYKYLNVPL 6905
Query 6821 EKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGT 6880
E+ L NYG LP G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAPG+
Sbjct 6906 ERVSLWNYGKPINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSDKEVAPGS 6965
Query 6881 AVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKE 6940
AVLRQWLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP TKN+
Sbjct 6966 AVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPLTKNIGDY 7025
Query 6941 NDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSS 7000
N SK+GFFTYIC I+ KL+LGGSVAIKITE SWNADLYKLM FA+WT F TNVNASSS
Sbjct 7026 NVSKDGFFTYICHLIRDKLSLGGSVAIKITEFSWNADLYKLMSCFAFWTVFCTNVNASSS 7085
Query 7001 EAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSL 7060
E FLIG NYLGK +IDG VMHANY+FWRN+ +YSLFDM+KF LKL GTAV++L
Sbjct 7086 EGFLIGINYLGKSSFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMTKFSLKLAGTAVVNL 7145
Query 7061 KEGQINDMILSLLSKGRLIIRENNRVVISSDVLVNN 7096
+ Q+ND++ SL+ +G+L++R+ + + D LVN
Sbjct 7146 RPDQLNDLVYSLIERGKLLVRDTRKEIFVGDSLVNT 7181
Score = 437 bits (1123), Expect = 2e-120, Method: Composition-based stats.
Identities = 197/1058 (19%), Positives = 368/1058 (35%), Gaps = 190/1058 (18%)
Query 13 HVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGVLPQLEQPYVFIK 72
HVQ +L +RD+ V + + V + +K GT L++ L + YV
Sbjct 71 HVQSNL----IRDIFVH---EDLHVVEVLTKTAVKSGTAILIKSPLHSLGGFPKGYVMGL 123
Query 73 RSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKN 126
+T +V+ L +G LG +VP G +P K + ++
Sbjct 124 FRSYKTK--RYVVHHLSMTTSTTNFGED--FLGWIVPF-GFMPSYVHKWFQFCRLYIEES 178
Query 127 GNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYV 186
+ D D E+ +P + + L+R+ G +V
Sbjct 179 DLIISNFKFDDYDFSVEDAYAEVHAEPKGKYSQK---------AYALLRQYRGIKPVLFV 229
Query 187 DNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSE 246
D C G +C++ +L + + + +AW+ R
Sbjct 230 DQYGCDYSGKLADCLQAY------GHYSLQDMRQKQSVW---LANCDFDIVVAWHVVRDS 280
Query 247 K-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGF 296
+ LQT I K D +G+ P + ++I+ + P + K
Sbjct 281 RFVMRLQTIATICGIKYVAQPTEDVVDGDVVIREPVHLLSADAIVLKL-PSLMKVMTHMD 339
Query 297 MGRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCE-FCGTENLTKE- 352
I+S+Y V +C + + C D+C W +G+ + C T + E
Sbjct 340 DFSIKSIYNV-DLCDCGFVMQYGYVDCFNDNCDFYGWVSGNMMDGFSCPLCCTVYDSSEV 398
Query 353 GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFS 412
A + G +P+N V+ + + G FG C++
Sbjct 399 KAQSSGVIPENPVL-----------------FTNSTDTVNHDSFNLYGYSVTPFGSCIY- 440
Query 413 YVGCHNKCAYWVPRASANIGC----NHTGVVGEGSEGLNDNLL-EILQKEKVNINIVGDF 467
+ W+P +++ ++GVVG S L+ L + V G+
Sbjct 441 WSPRPG---LWIPIIKSSVKSYDDLVYSGVVGCKSIVKETALITHALYLDYVQC-KCGNL 496
Query 468 KLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQK 527
+ N + G++ +Q++ + G++ +
Sbjct 497 EQNH-------------------ILGVNNSWCRQLLLNRGDYNM---------------- 521
Query 528 SILSPLYAFASEAARVVRSIFSRTLETAQNSVRV------------LQKAAITILDGISQ 575
+L + F R+ F+ + L ++ I +SQ
Sbjct 522 -LLKNIDLFVKR-----RADFACKFAVCGDGFVPFLLDGLIPRSYYLIQSGIFFTSLMSQ 575
Query 576 YSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW----------LTNIFGTVYEKL 624
+S + D + L + + V YI V +L +Q+ + N F T+ +
Sbjct 576 FSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDAS 635
Query 625 KPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNK 684
P WL + G+ F+ + A I AK + TFFKL+
Sbjct 636 APATGWLLYQLLNGL-----------FVVSQANFNFVALIPDYAKILVNKFYTFFKLL-- 682
Query 685 FLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSREETGLLMPLKA-PKE 738
L ++ LK +N +G F S GL G ++P A ++
Sbjct 683 -LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI---------PGFVLPCNAQEQQ 732
Query 739 IIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTPVCINGLMLLEIKDT 796
I F EG + E V+++ ++ ++ S E + P +CI M +
Sbjct 733 IYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGD 785
Query 797 EKYCALAPNMMV-TNNTFTLKGGAPTKVTFGDDTVI-EVQGYKSVNITFELDERIDKVLN 854
+ + + + + + A KV F + V+ E+ +V + F+LD D +L
Sbjct 786 KFFPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILG 845
Query 855 EKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDES 911
+ CS + VE G V++F VV DA+ L E + + L++ + YLFDE+
Sbjct 846 KVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQVRAFLNKLNENVVYLFDEA 905
Query 912 GEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQ 970
G+ +AS MYC+F D ED + E+ + + ++D +
Sbjct 906 GDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDDED---VVTGDNDDEDVVT 962
Query 971 PEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEV 1008
+ + E+ D+ + V D +++ T +V
Sbjct 963 GDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDV 1000
Score = 197 bits (502), Expect = 3e-48, Method: Composition-based stats.
Identities = 66/262 (25%), Positives = 109/262 (42%), Gaps = 18/262 (7%)
Query 1024 EVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAM 1083
E+ G L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A
Sbjct 1351 ELPQLYG-LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKF 1409
Query 1084 QVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQH 1141
E+ + + G +VG V +G L K L++VGP+ + LL AY++ N +
Sbjct 1410 SKETAAMVKSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNY 1469
Query 1142 EVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVE 1200
+ L+ L+SAGIF SL + V V L +K +D + + K +
Sbjct 1470 DCCLSTLISAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDIIQKCQITSVVGTKALA 1529
Query 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDI- 1259
++ +K K + C ++ ++E L ++ L D+
Sbjct 1530 VRLTANVGRVIKFETDAYKLFLSGD--------DCFVSNSSVIQEVLLLRHDIQLNNDVR 1581
Query 1260 -----NGNLHPDSATLVSDIDI 1276
P L++ D+
Sbjct 1582 DYLLSKMTSLPKDWRLINKFDV 1603
Score = 52.8 bits (125), Expect = 2e-04, Method: Composition-based stats.
Identities = 41/200 (21%), Positives = 73/200 (37%), Gaps = 21/200 (11%)
Query 1597 TYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKW 1656
D D + + + ++ Y L V D ++S + +
Sbjct 1091 VTGDNDDQIVVTGDDVDDIESIYDFDTYKALLV-------FNDVYNDALFVSYGSSVETE 1143
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1144 TYFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLT 1203
Query 1717 YCNKTVGEL--GDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
K + G V + + ++ N C CG L G++A+ + G +
Sbjct 1204 TIPKAIVLPQGGFVADFAYWFLNQFDI---NAYANWCCLKCGF-SFDLNGLDALFFYGDI 1259
Query 1775 SYEQFKKGVQIPCTCGKQAT 1794
V C CG T
Sbjct 1260 --------VSHVCKCGHNMT 1271
>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059
Score = 7602 bits (19725), Expect = 0.0, Method: Composition-based stats.
Identities = 2688/5594 (48%), Positives = 3609/5594 (65%), Gaps = 188/5594 (3%)
Query 1531 GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSM 1588
G + + G T +K L + + + TVD +N + V +
Sbjct 1530 GGIDICSQDKVFGYVQQGSFNKATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGE 1585
Query 1589 TYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMS 1648
++G+ G + DG +VTK K +++GK F+ N + ++A D L Y +
Sbjct 1586 SFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYN 1645
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAA 1708
L + KW+ + K A+NNC++ + L LQ + LKF Q+A+ R+G A
Sbjct 1646 MLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPA 1705
Query 1709 NFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAV 1768
F +L+LA G+ D R+ + +F +L + CK CG +Q GV+AV
Sbjct 1706 RFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAV 1764
Query 1769 MYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYT 1828
M+ GTLS E + G + C+CGK+ + V+ + PF++ S PA +L G + A+ +
Sbjct 1765 MHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLICSNTPASVKLPKGVGS-ANIFK 1822
Query 1829 GNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGV 1887
G+ + GHY H+ +++ D + + K ++ G ++D Y +N T TY LD V
Sbjct 1823 GD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDV 1881
Query 1888 VCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNASFDNFKFVCDNIKFADDLNQLTG 1946
E P L YY Y+T++ I + + NFK + + D LN G
Sbjct 1882 KKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGVYTNFKLIGHTV--CDILNAKLG 1939
Query 1947 YKKPA-SRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY 2003
+ E KVT +P GDVV Y +++G KP++W H + N TY
Sbjct 1940 FDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLTY 1999
Query 2004 KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLE 2063
++ + N FDVLK +D +++ D K E I L
Sbjct 2000 ----------FNRPLLVDENKFDVLKVDDVDDGGDISESDAK-------EPKEINIIKLS 2042
Query 2064 CNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTL- 2122
K +V +I+ + +K + + D+ ++ ++ N LSR + + T+
Sbjct 2043 GVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLTGCRCVVRTANALSRAVNVPTIR 2102
Query 2123 --ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLC 2180
G+ V S+P D + + VV N ++ C N++ + F LL
Sbjct 2103 KFIKFGMTLV-SIPIDLLNLREIKPVFNVVKAVRNKIS-----ACFNFIKWLFVLLFGWI 2156
Query 2181 TFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINII--IWFLLLSV 2238
+ K T +A + + +F K ++ II I+ L +
Sbjct 2157 KISA----DNKVIYTTEVASKLTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNF 2212
Query 2239 CLGSLIY--------------STAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTG 2284
++I+ + + + + + C Y + YC G
Sbjct 2213 IYANVIFSDFYLPKIGFLPTFVGKIVQWIKNTFSLVTICDLYSIQDVGF----KNQYCNG 2268
Query 2285 SIPCSVCLSGLDSLDTYPSLETIQITISS--FKWDLTAFGLVAEWFLAYILFTRFFYVLG 2342
SI C CL+G D LD Y +++ +Q F +V E ++Y L+T +FY L
Sbjct 2269 SIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF 2328
Query 2343 LAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
+Q+ ++ + ++ W + L+++L M P +R YI ASF ++ + HV
Sbjct 2329 ALISIQILTTWLPELLMLSTLHWSVRLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHV 2388
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GC+ S C+ CYKRNR+ RV+C+TIV G+ R + V ANGG GFC H WNC++CD++
Sbjct 2389 AYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKP 2448
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G+TFI+ E A DLS + KRPI PTD + + V V + L++D+ GQ+TY+ + S
Sbjct 2449 GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFYDRDGQRTYDDVNASL 2508
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FV+ NL + K ++V+V + + ++++ +A+V+Y+Q + +PIL++D+ L++
Sbjct 2509 FVDYSNLLHSKVKSVPNMHVVVVENDA--DKANFLNAAVFYAQSLFRPILMVDKILITTA 2566
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
V MFD YV+TF S F+V + L L+ATA + + + + VL TF+S AR+
Sbjct 2567 NTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQICKVLDTFLSCARKS 2626
Query 2641 F-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHI 2699
+DSDV+TK + + + + + +E+T +SCNN + TY K +N+ DLG I SA+H+
Sbjct 2627 CSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHV 2686
Query 2700 NAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIA 2759
VAK ++ IW+V F LS + +++ A K L +LT V+V+TT +
Sbjct 2687 QGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLELTYNKQMANVSVLTTPFS 2746
Query 2760 LKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRD 2819
LKGG + + ++ ++LV + + P + + K YK +D GV RD
Sbjct 2747 LKGGAVFSYFVYVCFVLSLVCFI---GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRD 2803
Query 2820 IASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILRTT 2877
++ D CFANK FD W+ G Y+N ACP++ AV+ ++ G V +P +LR
Sbjct 2804 VSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACPIVVAVVDQDFGSTVFNVPTKVLRY- 2862
Query 2878 NGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTN 2937
LHF+ SA G CYTP I Y++F S CVL++ CT+F A G P PYCY
Sbjct 2863 GYHVLHFITHALSADGVQCYTPHSQISYSNFYASGCVLSSACTMFAMADGSPQPYCYTDG 2922
Query 2938 VLEGSVAYESLRPDTRYVLMDG-SIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGV 2996
+++ + Y SL P RY L + I+ P EG VR+V T YCR G CE ++ G+
Sbjct 2923 LMQNASLYSSLVPHVRYNLANAKGFIRLPEVLREGLVRIVRTRSMSYCRVGLCEEADEGI 2982
Query 2997 CVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIV 3056
C + +G WVLNNDYYRSLPG FCG D +L+ +F L QP+ L ++AS +AG I+A++
Sbjct 2983 CFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVI 3042
Query 3057 VTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYL 3116
V YY ++ +RAFG+Y+ +V N +++ ++F +L + VY L VY++ Y Y T Y
Sbjct 3043 VVLGFYYLIKLKRAFGDYTSIVFVNVIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYF 3102
Query 3117 TNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE 3176
+++S + H+QW+VM+ ++P W + YI + + H +W FS R++ + S TFE
Sbjct 3103 PSEISVIMHLQWLVMYGTIMPLWFCLLYISVVVSNHAFWVFS--YCRQLGTSVRSDGTFE 3160
Query 3177 EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAK 3236
E AL TF++ K+ Y KL++ L +NRYL+LYNKY+Y+SG MDT +YREAAC LAK
Sbjct 3161 EMALTTFMITKDSYCKLKNS--LSDVAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAK 3218
Query 3237 ALNDF-SNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
A++ F +N+GSDVLYQPP S++++ LQSG KM P+ KVE C+V VT G TLNGLWL
Sbjct 3219 AMDTFTNNNGSDVLYQPPTASVSTSFLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWL 3278
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVD 3355
DD VYCPRHVIC++ DM NP+Y +LL R ++ +F V + L V+ + MQ C+L L V
Sbjct 3279 DDKVYCPRHVICSASDMTNPDYTNLLCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVT 3338
Query 3356 TANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNI 3415
N +TPKY F ++PG+TF+VLA YNG P G + MR ++TIKGSFL GSCGSVG+ I
Sbjct 3339 LQNSRTPKYTFGVVKPGETFTVLAAYNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVI 3398
Query 3416 DYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAV 3475
DCV F YMH +EL TG H GTD G+FYGP+ D Q Q D +VN +AWLYAA+
Sbjct 3399 MGDCVKFVYMHQLELSTGCHTGTDFNGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAI 3458
Query 3476 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL 3535
+N WF+ ++ DFN+ A+ + + D V + L++ TG+++ + A++K L
Sbjct 3459 LNNCNWFVQSDKCSVEDFNVWALSNGFSQVKSDLV--IDALASMTGVSLETLLAAIKRL- 3515
Query 3536 QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLV 3595
+NG GR I+GS EDE TP DV +Q +G+ QS R +KG W++ + ++
Sbjct 3516 KNGFQGRQIMGSCSFEDELTPSDVYQQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIIT 3575
Query 3596 QSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN-MVY 3654
+W++F ++ N L + + + AM+ VKHKH +L ++++P L T+ Y N +V
Sbjct 3576 AFVKWTMFMYVTTN-MLSITFCALCVISLAMLLVKHKHLYLTMYIIPVLFTLLYNNYLVV 3634
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL-LILMTARTVYDDGARRVWTLMN 3713
++ + WL S+ + D V+Y +++ ++ +T R++ D + +
Sbjct 3635 YKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGMLLLIGMVFVTLRSINHDLFSFIMFVGR 3693
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+++V Y G+ L++ I + ++ S+ Y+ M A+ ++ V ++F
Sbjct 3694 VISVVSLWYMGSNLEEEILL--MLASLFGTYTWTTALSMAAAK-VIAKWVAVNVLYFTDI 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
++ +++ Y F+GY +CY+GLF L+N FR+ LGVY+Y +S QE RYMN+ GL PPKN
Sbjct 3751 PQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKN 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
S +A LN KLLG+GG P I+V+ QSK++DVKC + LL+ LQ L V S+SKLW C
Sbjct 3811 SFEALMLNFKLLGIGGVPIIEVSQFQSKLTDVKCANGGLLNCLQHLHVASNSKLWQYCST 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQAIASE 3947
LHN+IL D AFEK+ LL VL + AVD I ++C++ + LQA+ SE
Sbjct 3871 LHNEILATSDLGVAFEKLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSE 3930
Query 3948 FSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMAD 4006
F ++ S+ + A++ ++A ++G + + LK+L+K+ N+AKS ++RD A+ RKLE+MAD
Sbjct 3931 FVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAYERDRAVARKLERMAD 3990
Query 4007 QAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTT 4066
A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 3991 LALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLA 4050
Query 4067 AAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPL 4126
A L +++PD + Y D TYA +W+IQ + D+D QL EIS D + WPL
Sbjct 4051 ANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLHEISDDCN----WPL 4106
Query 4127 IVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLAL 4184
++ A R N SA LQNNEL P L+ +G QT T YYN + G+ V A+
Sbjct 4107 VIIANRHNEVSATVLQNNELMPAKLKTQVVNSGPDQTCNTPTQ--CYYNNSYNGKIVYAI 4164
Query 4185 LSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLG 4244
LSD+ LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V+G
Sbjct 4165 LSDVDGLKYTKILKDDGN-FVVLELDPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVG 4223
Query 4245 SLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGT 4304
++++TVRLQAG ATE +NS++LS CAF+VD K Y D++ GG PI NCVKMLC H GT
Sbjct 4224 TISSTVRLQAGTATEYASNSSILSLCAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGT 4283
Query 4305 GQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFT 4364
G AITV P+A Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV +
Sbjct 4284 GMAITVKPDATTSQDSYGGASVCIYCRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYV 4342
Query 4365 LKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA-ARLTPCGTGTSTDVV 4423
L + VC VCG W+ CSC + +QS D +FLNRV G S ARL PC +G STDV
Sbjct 4343 LTHDVCQVCGFWRDGSCSCVST-DTTVQSKDT-NFLNRVRGTSVDARLVPCASGLSTDVQ 4400
Query 4424 YRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLK 4483
RAFDI N VAG LK NCCRFQ DE+ + +D +FVVKR + Y E Y +K
Sbjct 4401 LRAFDICNASVAGIGLHLKVNCCRFQRVDENGDKLDQFFVVKRTDLTIYNREMECYERVK 4460
Query 4484 DCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNC 4543
DC VA+HDFF F ++G VPHI R+ LTKYTM DL YALRHFD +C L +IL Y
Sbjct 4461 DCKFVAEHDFFTFDVEGSRVPHIVRKDLTKYTMLDLCYALRHFDRNDCMLLCDILSIYAG 4520
Query 4544 CDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQD 4603
C+ YF KKDWYDFVENPDI+ VY LG +AL+ +F D + G+VG+LTLDNQD
Sbjct 4521 CEQSYFTKKDWYDFVENPDIINVYKKLGPIFNRALVSATEFADKLVEVGLVGILTLDNQD 4580
Query 4604 LNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLL 4663
LNG WYDFGD++ PG GV + DSYYS +MP+LT+ AL E +V+ Y +DL+
Sbjct 4581 LNGKWYDFGDYVIAAPGCGVAIADSYYSYMMPMLTMCHALDCELYVNN----AYRLFDLV 4636
Query 4664 KYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVR 4723
+YDFT+ +L+LF++YFK+W YHPN V+C DDRCI+HCANFN+LFS V P T FGPLVR
Sbjct 4637 QYDFTDYKLELFNKYFKHWSMPYHPNTVDCQDDRCIIHCANFNILFSMVLPNTCFGPLVR 4696
Query 4724 KIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDK 4783
+IFVDGVPFVVS GYH++ELG+V N DV+ H RLS K+LL+YAADPA+H AS + L D
Sbjct 4697 QIFVDGVPFVVSIGYHYKELGIVMNMDVDTHRYRLSLKDLLLYAADPALHVASASALYDL 4756
Query 4784 RTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAIS 4843
RT CFSVAA+T+ V FQTVKPGNFN+DFYDF +SKG KEGSSV+LKHFFF QDGNAAI+
Sbjct 4757 RTCCFSVAAITSGVKFQTVKPGNFNQDFYDFILSKGLLKEGSSVDLKHFFFTQDGNAAIT 4816
Query 4844 DYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGK 4903
DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGGCI A QVIVNN DKSAG+PFNK+GK
Sbjct 4817 DYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGGCIPAAQVIVNNYDKSAGYPFNKFGK 4876
Query 4904 ARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQF 4963
ARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI STMT R F
Sbjct 4877 ARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILSTMTGRMF 4936
Query 4964 HQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLR 5023
HQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV+NP LMGWDYPKCDRAMPN+LR
Sbjct 4937 HQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDNPVLMGWDYPKCDRAMPNILR 4996
Query 5024 IMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYAN 5083
I++SLVLARKH CCS S RFYRLANECAQVLSE+VMCGG YVKPGGTSSGDATTA+AN
Sbjct 4997 IVSSLVLARKHEACCSQSDRFYRLANECAQVLSEIVMCGGCYYVKPGGTSSGDATTAFAN 5056
Query 5084 SVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRK 5143
SVFNICQAV+ANV AL+S +GNKI D +R LQ RLY +YR+ VD+ FV E+Y +L K
Sbjct 5057 SVFNICQAVSANVCALMSCNGNKIEDLSIRALQKRLYSHVYRSDMVDSTFVTEYYEFLNK 5116
Query 5144 HFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHE 5203
HFSMMILSDD VVC+NS YAS+G +A+I F+ VLYYQNNVFMSE+KCW E D+ GPHE
Sbjct 5117 HFSMMILSDDGVVCYNSDYASKGYIANISAFQQVLYYQNNVFMSESKCWVENDINNGPHE 5176
Query 5204 FCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTK 5263
FCSQHTMLVK D VYLPYP PSRILGAGCFVDD++KTD L+IERFVSLAIDAYPL
Sbjct 5177 FCSQHTMLVKMDGDDVYLPYPVPSRILGAGCFVDDLLKTDSVLLIERFVSLAIDAYPLVY 5236
Query 5264 HPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVL 5323
H N+EY VF +YL+YI+KL++EL +LD YSV+L+ + ++ + FY+ MY V+
Sbjct 5237 HENEEYQKVFRVYLEYIKKLYNELGNQILDSYSVILSTCDGQKFTDESFYKNMYLRSAVM 5296
Query 5324 QAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTD 5383
Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV++T HK VLSV+PYVCNAPGCDV D
Sbjct 5297 QSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHVMATDHKYVLSVSPYVCNAPGCDVND 5356
Query 5384 VTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGD 5443
VT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS + DFN IA+C WT+ D
Sbjct 5357 VTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYIDDFNRIASCKWTDVDD 5416
Query 5444 YILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRN 5503
YILAN CTERLKLFAAET KATEE FK SY AT++E++S+REL LSWE+GK +PPLN+N
Sbjct 5417 YILANECTERLKLFAAETQKATEEAFKQSYASATIQEIVSERELILSWEIGKVKPPLNKN 5476
Query 5504 YVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPT 5563
YVFTGY TKN K +GEY F+K + + V YR TTTYKL+VGD FVLTSH+V LSAPT
Sbjct 5477 YVFTGYHFTKNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFVLTSHSVANLSAPT 5536
Query 5564 LVPQEHYV--RITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLAL 5621
LVPQE+Y R +Y L + F +NV NYQ +GM++Y T+QGPPGTGKSH AIGLA+
Sbjct 5537 LVPQENYSSIRFASVYSVL---ETFQNNVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAV 5593
Query 5622 YYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVF 5681
YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RVEC+DKFK+N T +YVF
Sbjct 5594 YYCTARVVYTAASHAAVDALCEKAYKFLNINDCTRIVPAKVRVECYDKFKINDTTRKYVF 5653
Query 5682 CTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTL 5741
T+NALPE DIVV DE+SM TNY+LSV+NAR+RAKHYVYIGDPAQLPAPR LL+KGTL
Sbjct 5654 TTINALPEMVTDIVVVDEVSMLTNYELSVINARIRAKHYVYIGDPAQLPAPRVLLSKGTL 5713
Query 5742 EPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYK 5801
EP+YFN+V +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA + S+ CFK++YK
Sbjct 5714 EPKYFNTVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYENKLKAKNESSSLCFKVYYK 5773
Query 5802 GVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQ 5861
GV TH+ SSA+N QI ++ +FL NP W KAVFISPYNSQN A ++LGL TQTVDS+Q
Sbjct 5774 GVTTHESSSAVNMQQIYLINKFLKANPLWHKAVFISPYNSQNFAAKRVLGLQTQTVDSAQ 5833
Query 5862 GSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNV 5921
GSEYDYVI++QT ETAHS NVNRFNVAITRAK GILC+MS+ L++ LQFT+L + +
Sbjct 5834 GSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSNMQLFEALQFTTLTVDKVPQ 5893
Query 5922 A-TLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRL 5979
A + + T LFKDCSK +G HP AP+ L+VD K+K T L V + +TY RL
Sbjct 5894 AVETRVQCSTNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRL 5953
Query 5980 ISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTG 6039
IS+MGFK++ ++GY +FIT+EEA++ VRAW+GFD EG HATR+++GTN PLQLGFSTG
Sbjct 5954 ISLMGFKLDVTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTG 6013
Query 6040 VNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTL 6099
++ V TG + F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L
Sbjct 6014 IDFVVEATGLFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHL 6073
Query 6100 KNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFD 6159
+LSD VV V WA FELT ++YF K+G E +C + +RAT +++ + Y CW HS+ D
Sbjct 6074 IDLSDCVVLVTWAANFELTCLRYFAKVGREISCNVSTKRATAYNSRTGYYGCWRHSVTCD 6133
Query 6160 YVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTI 6219
Y+YNP ++D+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +
Sbjct 6134 YLYNPLIVDIQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNV 6193
Query 6220 EYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQ 6279
EYPII +EL IN +CR +Q +++KAA+L +++ + +DIGNPKAI CV D ++KFYDAQ
Sbjct 6194 EYPIISNELSINTSCRVLQRVMLKAAMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQ 6251
Query 6280 PCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGC 6339
P ++ L Y + H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC
Sbjct 6252 PI---VKSVKTLLYFFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGC 6308
Query 6340 DGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCI 6399
+GGSLYVNKHAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCI
Sbjct 6309 NGGSLYVNKHAFHTKPFSRAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCI 6368
Query 6400 TRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAF 6459
TRCNLGGAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQSLENV +
Sbjct 6369 TRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTKLQSLENVVY 6428
Query 6460 NVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVP 6519
N+V GH+ GQ GE+P +IIN+ V K+D DV +F N TT P NVA EL+AKR+I+ P
Sbjct 6429 NLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHP 6488
Query 6520 EVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRV 6579
E+K+ NL +D+ VIWDY R++ +T GVC TD+ + L V FDGR
Sbjct 6489 ELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------LIDKLNVLFDGRD 6542
Query 6580 DGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI---GEAVKTQFNYYKKVDG 6636
+G ++ F+ + NGV I+ VK L GP +A LNGV + F K+
Sbjct 6543 NGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQD 6602
Query 6637 VVQQLPE-------------------------------TYFTQSRNLQEFKPRSQMEIDF 6665
V+ + T FTQSR + F R+ ME DF
Sbjct 6603 VIFSQFDSLRVSSNQSPQGNLGSNEPGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDF 6662
Query 6666 LELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDS 6725
+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S +++F+ DS
Sbjct 6663 IALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDS 6722
Query 6726 TVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWC 6785
++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+ + FMLWC
Sbjct 6723 SIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWC 6782
Query 6786 KDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKY 6845
D V TFYP+LQ++ W+PG +MP LYK +E+ L NYG TLP G MMNVAKY
Sbjct 6783 NDEKVMTFYPRLQAASDWKPGYSMPVLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKY 6842
Query 6846 TQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAV----------LRQWLPTGTLLVD 6895
TQLCQYLNT TLAVP N RV+H GAGS+KGVAPG+AV LRQWLP GT+LV
Sbjct 6843 TQLCQYLNTTTLAVPVNTRVLHLGAGSEKGVAPGSAVLRQWLPAGTILRQWLPAGTILVH 6902
Query 6896 SDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYI-CGF 6954
+DL FVSD+ +T GDC T+ +WDLIISDMYD +YI C
Sbjct 6903 NDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMYDLLLDIGVHVVRC-----SYIHCHM 6957
Query 6955 IQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPR 7014
I+ KLALGGSVAIKITE SWNA+LYKLMG+FA+WT F TN NASSSE FLIG NYLGKP+
Sbjct 6958 IRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTVFCTNANASSSEGFLIGINYLGKPK 7017
Query 7015 EQIDGYVMHANYIF 7028
+IDG VMHA F
Sbjct 7018 VEIDGNVMHAIICF 7031
Score = 647 bits (1668), Expect = 0.0, Method: Composition-based stats.
Identities = 227/1040 (22%), Positives = 374/1040 (36%), Gaps = 183/1040 (18%)
Query 43 RQHLKDGTCGLVEVE----------KGVLPQLEQPYVFIKRSDA---RTAPHGHVMVEL- 88
+ L+ LV +G P +F +RS R A + HV +L
Sbjct 94 QDALQSREAVLVTPPLGMSLEACYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAYQLY 153
Query 89 VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKNGNKGA-------GGHS 135
+ + G+ +G +G+ +G ++P + +PV RK + LRK G KGA GG
Sbjct 154 MIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIAPWVMYLRKCGEKGAYIKDYKRGGFE 211
Query 136 YGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
+ + K D D + +P F + L+R G YVD C G
Sbjct 212 HVYNFKVEDAYDLVHDEPKGKFSKK---------AYALIRGYRGVKPLLYVDQYGCDYTG 262
Query 196 ---YPLECIKDLLARAGKASCTL-SEQLDFIDTKRGVYCCREHEHEIAWYTERSEK-SYE 250
LE D + KA + S++L F + +AW+ R +
Sbjct 263 GLADGLEAYADKTLQEMKALFPIWSQELPF-------------DVTVAWHVVRDPRYVMR 309
Query 251 LQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFM---- 297
LQ+ I+ D +G P V+ +SII + + L M
Sbjct 310 LQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYADDSII------LRQHNLVDIMSCFY 363
Query 298 ----GRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCEF-CGTENLT 350
+ + Y V +C + + C D C W G+ + CG T
Sbjct 364 MEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCDFKGWVPGNMIDGFACTTCGHVYET 422
Query 351 KEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGC 409
+ A + G LP N V+ A + G + S Y G + FGGC
Sbjct 423 GDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFTLY------------GQTVVYFGGC 469
Query 410 VFSYVGCHNKCAYWVPRASANI----GCNHTGVVGEGSEGLNDNL-LEILQKEKVNINIV 464
V+ + N W+P +++ G +TGVVG + NL + L + V +
Sbjct 470 VY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGCKAIVKETNLICKALYLDYVQ-HKC 524
Query 465 GDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNI- 523
G+ E + + S L+ +K ++E+ F + + K + +
Sbjct 525 GNLHQRELLGV---------SDVWHKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVC 575
Query 524 --GEQKSILSPLY-----------AFASEAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
G +L L AF A ++ ++ S++ E SV L AAI L
Sbjct 576 ADGFMPFLLDDLVPRAYYLAVSGQAFCDYAGKICHAVVSKSKELLDVSVDSL-GAAIHYL 634
Query 571 DGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDW 630
+ +++D SD T+ +V + T+ L VL
Sbjct 635 NS------KIVDLAQHFSDFGTS-------FVSKIVHFFKTFTTSTALAFAWVLFHVLHG 681
Query 631 LEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCA 690
+ + F ++ I ++ S V + AK +S++ F +
Sbjct 682 AYIVVESDIYFGKN---IPRYASA-----VAQAFRSGAKVGLDSLRVTFIDGLSCFKIGR 733
Query 691 DSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMP---LKAPKEIIFLEGETL 747
I + G+K+ + G + HS L + L MP K ++ I+L+G
Sbjct 734 RRICLSGSKIYEVERG---LLHSSQL------PLDVYDLTMPSQVQKTKQKGIYLKGSGS 784
Query 748 PTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMM 807
+ V + T L P E P V +CI + + + Y + +
Sbjct 785 DFSLADSVVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDGHV 839
Query 808 VTNNTFTLKGGAPTKVTFGDDT-VIEVQGY-KSVNITFELDERIDKVLNEKCSAYTVELG 865
+ A VTF + V E+ K++ + +ELD+ + +LN C + V+
Sbjct 840 GLLDQAWRVPCAGRCVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGEFEVDDT 899
Query 866 TEVNEFACVVADAVIKTLQPVSEL---LTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
++ EF VV DA+ + L P EL + L + + +LFDE+GE LA +YC
Sbjct 900 VDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGEEVLAPKLYC 959
Query 923 SFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQE--EDWL 980
+F P++D D EE E D G A + EE E ED L
Sbjct 960 AFTAPEDD----DFLEESGVEEDDVEGEETD---LTVTSAGEPCVASEQEESSEILEDTL 1012
Query 981 DDDSQQTVGQQDGSEDNQTT 1000
DD ED Q +
Sbjct 1013 DDGPCVETSDSQVEEDVQMS 1032
Score = 194 bits (494), Expect = 3e-47, Method: Composition-based stats.
Identities = 59/251 (24%), Positives = 111/251 (44%), Gaps = 17/251 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D +
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + T + V L ++ +D + ++ K++ ++++
Sbjct 1392 AGIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLISKCQITAVEGTKKLAERLSFNVGR 1451
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+ +K + L++ L ++ L ++ N ++
Sbjct 1452 SIVYETDANKLILSNDVA--------FVSTFNVLQDVLSLRHDIALDDDARTFVQSNVDV 1503
Query 1264 HPDSATLVSDI 1274
P+ +V+
Sbjct 1504 VPEGWRVVNKF 1514
Score = 48.9 bits (115), Expect = 0.003, Method: Composition-based stats.
Identities = 41/196 (21%), Positives = 73/196 (37%), Gaps = 22/196 (11%)
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
++ +V L K NNC+L + L +Q++ +F LQD + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1717 Y--CNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
N V + G V + + L + V C C LKG++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1775 SYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCG 1834
V C CG+ L+ + PF A + LK F Y+
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPFT------AHFALKDKLFCAFITKRSVYKAA 1216
Query 1835 HYKHITSKETLYCIDG 1850
+ ++ +DG
Sbjct 1217 CVVDVNDSHSMAVVDG 1232
>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793
Score = 6841 bits (17749), Expect = 0.0, Method: Composition-based stats.
Identities = 2324/5134 (45%), Positives = 3187/5134 (62%), Gaps = 193/5134 (4%)
Query 2000 KATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQK 2059
+T T + + ST V S VLK G+D+ C P+ + VV
Sbjct 1814 TSTTCDGTCSTKRVVSTPVVNAS----VLKV----GLDDGNCVHGLPLVDRVVSVNGTVI 1865
Query 2060 DVLECNVKTTEVVG-DIILKPANNSLKITEEVGHTDLMAAYVDNSSLT----IKKPNELS 2114
+ VV + +L + + + + L + KP +L+
Sbjct 1866 ITNVGDTPGKPVVATENLLLDGVSYTVFQDSTTGVGHYTVFDKEAKLMFDGDVLKPCDLN 1925
Query 2115 RVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVT--RCLNRVCTNYMPYF 2172
+ + V P + A FL+ + + T ++R + Y
Sbjct 1926 VSPVTSVVVCNNKKIVVQDPVKRVELDASKFLDTMNVASEKFFTFGDFVSRNIIVLIVYL 1985
Query 2173 FTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIW 2232
F+LL + + ++ A +P +SV K+ +A + + I
Sbjct 1986 FSLLAICFRALKKRDMKVMAGVPERTGIILKRSV-KYNYKALKFFFRLK-----FQYIKV 2039
Query 2233 FLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCL 2292
FL S+ L +L Y+ + + + +G P C Y +GY NST YC + C +CL
Sbjct 2040 FLKFSLVLYTL-YALMFMFIRFTPVGTP-ICKRYTDGYANST-FDKNDYCGN-VLCKICL 2095
Query 2293 SGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFS 2352
G + L + I + L L + + I+F FF +G+ + + +
Sbjct 2096 YGYEELSDFTHTRVIWQHLKDP---LIGNILPLFYLVFLIIFGGFFVRIGITYFIMQYIN 2152
Query 2353 Y--FAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCM 2410
A+ + N WL+ L+ P ++M + + + HV+ GC+ +C+
Sbjct 2153 AAGVALGYQDNVWLLHLL-------PFNSMGNIIVVAFIVTRILLFLKHVLFGCDKPSCI 2205
Query 2411 MCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVA 2470
C K + TRV TI+ GV +SFYV ANGGK FCK HN+ CV+CD++ G TFI+D +A
Sbjct 2206 ACSKSAKLTRVPLQTILQGVTKSFYVNANGGKKFCKKHNFFCVDCDSYGYGCTFINDVIA 2265
Query 2471 RDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRAN 2530
+LS K + PT ++ I+D V NG +LY K + + + D L+
Sbjct 2266 PELSNVTKLNVIPTGPATIIIDKVEFSNGFYYLYSGSTFWKYNFDITEAKYACKDVLKNC 2325
Query 2531 NTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKM 2590
N + + +VF S + K+A VY+SQL+C+PI L+D AL++ + + + +
Sbjct 2326 N----ILTDFVVF-NNSGSNVTQVKNACVYFSQLLCKPIKLVDSALLASLN--VDFSANL 2378
Query 2591 FDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKD 2650
A+V S++F + + + R+ SDV ++
Sbjct 2379 HKAFVEVLSNSFGKDLSNCSNM----------------------NECRESLGLSDVPEEE 2416
Query 2651 VVECLKLSHQSDIEVTGDSCNNYMLTYNKVE-NMTPRDLGACIDCSARHINAQVAKSHNI 2709
+ +H+ D+ ++ S NN +++Y K E + D+ C+ A+ +N V N+
Sbjct 2417 FSAAVSEAHRYDVLISDVSFNNLIVSYAKPEEKLAVHDIANCMRVGAKVVNHNVLTKDNV 2476
Query 2710 ALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNW 2769
++W KDF++LSE+ RK I K + F LT R + + T +A K G + +
Sbjct 2477 PVVWLAKDFIALSEEARKYIVRTTKTKGINFMLTFNDRRMHLTIPTISVANKKGAGLPSL 2536
Query 2770 LKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEI-----IGYKAIDGGVTRDIASTD 2824
+L + F + LI + V + DFS+++ +K I+ GV +
Sbjct 2537 FTRL------YSFFWHLCVLIVVLFVATSLLDFSAQVTSDTQYDFKYIENGVLKVFEKPL 2590
Query 2825 TCFANKHADFDTWFSQRGGS-YTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLH 2883
C N +F+ W + + GS TN + CP++ +PG+P + G L
Sbjct 2591 DCVHNAFVNFNEWHNAKFGSIPTNSRRCPIVVGTSDEV--RYIPGVPAGVFLY--GKSLI 2646
Query 2884 FLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSV 2943
F +C+ L + +C+ + CT G+ V YCY V++ +
Sbjct 2647 FAMSTIFGTSGLCFDDRGLTD-----PDSCIFNSACTTLSGIGGRNV-YCYREGVVDNAK 2700
Query 2944 AYESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCERSEAGVCVSTSG 3002
Y SL P + Y LMDG+ I P G +R + T YCR G C S+AGVCV
Sbjct 2701 LYSSLLPHSYYRLMDGNHIVLPEIITRGFGIRTIKTQAMTYCRTGECIDSQAGVCVGLDR 2760
Query 3003 RWVLNNDYYRSLPG--VFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
+V Y PG CG +LL N+ I +S I+ +VA
Sbjct 2761 FFV-----YSKTPGSDYVCGTGFFSLLFNVIGMFSNSIPVTVMSGQILLNCVVAFTAVMA 2815
Query 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
+ F +F+R FG+ S V L +++ +T + + Y L F T V
Sbjct 2816 CFAFTKFKRLFGDMSFGVLSVGLCTVVNNLSYVVTQ-----NSIGMLAYATLYFLCTKGV 2870
Query 3121 --SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFNGVSF-ST 3174
S++ H+ + + + L P+W+ +AY+IC F N K +V +F G F +
Sbjct 2871 RYSWVWHVGFAISYCFLAPWWVVLAYLIC----ALLEFLPNLFKLKVSTQLFEGDKFVGS 2926
Query 3175 FEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL 3234
FE AA TF+L+ Y KL + + + +Y A YN+YKY+SG+ YR A HL
Sbjct 2927 FESAASGTFVLDMHSYQKLANSI--STEKLKQYCASYNRYKYYSGSASEADYRLACFAHL 2984
Query 3235 AKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW 3294
AKA++DF+N D LY PP S S LQ+G RKMA PSG VEGC+V+V+ G TLNGLW
Sbjct 2985 AKAMSDFANDHMDKLYTPPTVSYNST-LQAGLRKMAQPSGIVEGCIVRVSYGNLTLNGLW 3043
Query 3295 LDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKV 3354
L D V CPRHVI ++ +Y+ + HNF + +GN+ L VI SM+ +L +KV
Sbjct 3044 LGDTVICPRHVIASNTT-NVIDYDHAMSLVRLHNFSISSGNMFLGVISASMRGTLLHIKV 3102
Query 3355 DTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFN 3414
+ +N TP Y + ++PG +F++LACY+GS +GVY MR N+TI+GSF++G+CGS G+N
Sbjct 3103 NQSNVNTPNYTYKVLKPGDSFNILACYDGSAAGVYGVNMRTNYTIRGSFISGACGSPGYN 3162
Query 3415 IDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAA 3474
I+ V FCYMHH+EL +G H G+D++G YG + D+ T Q G +T NV +WLY A
Sbjct 3163 INNGVVEFCYMHHLELGSGCHVGSDMDGTMYGKYEDQPTLQIEGASNLVTENVCSWLYGA 3222
Query 3475 VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKEL 3534
+INGDRW+L+ + ++ +N A++ L +VD L A+TG+ V + AS+++L
Sbjct 3223 LINGDRWWLSSVSVGVDTYNEWALRNGMTALK--NVDCFSLLVAKTGVDVGRLLASIQKL 3280
Query 3535 LQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSA-VKRTIKGTHHWLLLTILTSLLV 3593
N G++ILG L DEFT +VV+Q GVT QS V R + +I+ LL
Sbjct 3281 HGN-FGGKSILGCTSLCDEFTLSEVVKQMYGVTLQSGKVSRAFRN------ASIVCCLLF 3333
Query 3594 LVQSTQW--SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN 3651
L S S F++ P + II S+ M+ VKHK FL L+LLPSL V+ +N
Sbjct 3334 LFLSEMLNHSKLFWINPGYITPVFLAIIVASSALMLLVKHKLLFLQLYLLPSLCIVSGYN 3393
Query 3652 MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVW-T 3710
++ + ++ D GF + + + ++ L T R + +++
Sbjct 3394 -IFKDYHFYTYMLEEFDY-KVPFGGFNVTGVLNISLCCFVMGLHTFRFL--QTPNKIFSY 3449
Query 3711 LMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFF 3770
++ VLT++Y YY + + +S +NY + T LA +
Sbjct 3450 VVAVLTVLYTYYYS---TDVLGLILTSMSGFTNYWFIGTATYKLATYV-----LPHTSLL 3501
Query 3771 ITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLP 3830
+ + ++ ++ +Y LGY Y+G +NR+ +LTLG Y++ VS EF+YM + GL
Sbjct 3502 DSFDAIKAVVFLYLLLGYCNCVYYGSLYWINRFCKLTLGCYEFKVSAAEFKYMVANGLRA 3561
Query 3831 PKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQ 3890
P DA L++KL+GVGG+ IK+++VQSK++D+KCT+VVLL L + + ++S+ WA
Sbjct 3562 PTGVFDALILSLKLIGVGGRKTIKISSVQSKLTDLKCTNVVLLGCLSNMNIAANSREWAY 3621
Query 3891 CVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSS 3950
CV LHN I L D A E +++LL+ LS A +++L + ++ + LQ++A+ + +
Sbjct 3622 CVDLHNKINLCNDAEAAQEMLLALLAFFLSKNSAFGVDELLDSYFNDSSVLQSVAATYVN 3681
Query 3951 LPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMT 4010
LPSY A+ TA+++YE A+ANG ++K+L+ ++NVAKSEFDR+A+ QRKL++MA+QA +
Sbjct 3682 LPSYLAYETARQSYEDALANGSPPQLVKQLRHAMNVAKSEFDREASTQRKLDRMAEQAAS 3741
Query 4011 QMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKL 4070
QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I++ A+DG VPL+IIP +A KL
Sbjct 3742 QMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLAKDGVVPLSIIPAVSATKL 3801
Query 4071 MVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTA 4130
+V+ D +Y YA +W + + D D K V E+ N +LAWPL +
Sbjct 3802 NIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAKEVVTSNVESLAWPLFLNC 3861
Query 4131 LRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQD 4190
R +KLQNNE+ P ++Q A D NAL Y+ G F+ A +SD D
Sbjct 3862 ER---IIKLQNNEIIPSKIKQRPIKAEGE-GVVADGNAL--YSNEGGRTFMYAFISDKPD 3915
Query 4191 LKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATV 4250
LK ++ G+ I ELEPPC+F+ + P GP VKYLYF++ LNNL RG VLG + ATV
Sbjct 3916 LKVVKWEFDGGSNAI--ELEPPCKFLVEAPSGPVVKYLYFVRNLNNLRRGAVLGFIGATV 3973
Query 4251 RLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITV 4310
RLQAG TE NS++L+ CAFAVD K Y D + SG +P+ NCVKML +G GQAIT
Sbjct 3974 RLQAGKQTEQATNSSLLTLCAFAVDPPKTYLDAVKSGHRPVGNCVKMLANGSGNGQAITN 4033
Query 4311 TPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVC 4370
EA+ +Q+S+GGAS CLYCR H++HP+ GFC L+GKYVQ+P DP+ F L+NTVC
Sbjct 4034 GVEASTNQDSYGGASVCLYCRAHVEHPDMDGFCKLRGKYVQVPLGTL-DPIRFVLENTVC 4092
Query 4371 TVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIY 4430
VCG W+ GC+CD+ ++QS D +LNRV G SAARL P G+ T V+RAFD+Y
Sbjct 4093 KVCGCWQANGCTCDR---AVIQSVD-SGYLNRVRGSSAARLEPL-NGSDTHHVFRAFDVY 4147
Query 4431 NDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAK 4490
N VA +KFLK NC R + D+ D++++VK+ T S +HE++IYNL+ DC AVAK
Sbjct 4148 NRDVACISKFLKVNCVRLKNLDKH----DAFWIVKKCTKSVMEHEQSIYNLISDCGAVAK 4203
Query 4491 HDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFN 4550
HDFF ++ + ++ RQ LT+YTM DL YALR+FDE NC+TLK+ILV CD+ YF+
Sbjct 4204 HDFFTWKEGRSVYGNVCRQDLTEYTMMDLCYALRNFDENNCETLKKILVVVGACDESYFD 4263
Query 4551 KKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYD 4610
K W+D VEN D+ RVYA LG V +A+LK V++CDAM GIVGV+TLDNQDLNG++YD
Sbjct 4264 NKLWFDPVENEDVHRVYAKLGTIVARAMLKCVKYCDAMVEQGIVGVITLDNQDLNGDFYD 4323
Query 4611 FGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDL-TKPYIKWDLLKYDFTE 4669
FGDF+ + G GVP+ SYYS +MP++ +T L +E + +D+ + + +DLL YDFTE
Sbjct 4324 FGDFVTSVKGMGVPICTSYYSYMMPVMGMTNCLASECFIKSDIFGEDFRTFDLLAYDFTE 4383
Query 4670 ERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDG 4729
++ LF++YFK+W QTYHPNC +C D+ CI+HCANFN LF+T P T+FGPL RK ++DG
Sbjct 4384 HKVNLFNKYFKHWGQTYHPNCEDCHDESCIVHCANFNTLFATTIPITAFGPLCRKCWIDG 4443
Query 4730 VPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFS 4789
VP V + GYHF++LG+V N+D+NLHSSRL+ ELL + ADP++ AS L+DKRT CFS
Sbjct 4444 VPLVTTAGYHFKQLGIVWNKDLNLHSSRLTINELLQFCADPSLLIASSPALVDKRTVCFS 4503
Query 4790 VAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYR 4849
VAAL + QTVKPG+FN++FYDF S+GFF+EGS + LKHFFFAQ G+AA+ D+DYYR
Sbjct 4504 VAALGTGMTNQTVKPGHFNREFYDFLRSQGFFEEGSELTLKHFFFAQKGDAAVRDFDYYR 4563
Query 4850 YNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYD 4909
YN T+ DI Q V ++V YF Y+GGCI A +VIVNNL+KSAG+PFNK+GKA LYYD
Sbjct 4564 YNRTTVLDICQARVVYQIVQCYFGMYEGGCITAKEVIVNNLNKSAGYPFNKFGKAGLYYD 4623
Query 4910 SMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLK 4969
S+SYE+QD L+AYTKRN+IPT+TQ+NLKYAIS K+RARTV GVS+ STMT RQ+HQK LK
Sbjct 4624 SLSYEEQDDLYAYTKRNIIPTMTQLNLKYAISGKDRARTVGGVSLLSTMTTRQYHQKHLK 4683
Query 4970 SIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLV 5029
SI TRGA+VVIGT+KFYGGW NMLKT+ DVENPHLMGWDYPKCDRA+PNM+R++++++
Sbjct 4684 SIVNTRGASVVIGTTKFYGGWDNMLKTLIKDVENPHLMGWDYPKCDRALPNMIRMISAMI 4743
Query 5030 LARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNIC 5089
L KH CCS S R+YRL NE AQVL+EMV G YVKPGGT+SGDATTAYANSVFNI
Sbjct 4744 LGSKHVNCCSSSDRYYRLCNELAQVLTEMVYSNGGFYVKPGGTTSGDATTAYANSVFNIF 4803
Query 5090 QAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMI 5149
QA +ANVN LLS D N + V+ LQ +LY+C YR+ VD FV E++ YLRKHFSMMI
Sbjct 4804 QATSANVNRLLSVDSNTCNNIEVKQLQRKLYDCCYRSSSVDQSFVEEYFGYLRKHFSMMI 4863
Query 5150 LSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHT 5209
LSDD VVC+NS YA+ G VA + FK+VLYYQNNVFMS +KCW E D+ KGPHEFCSQHT
Sbjct 4864 LSDDGVVCYNSEYAALGYVADLNAFKAVLYYQNNVFMSASKCWIEPDINKGPHEFCSQHT 4923
Query 5210 MLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEY 5269
M + D YLPYPDPSRIL AG FVDDIVKTD +++ER+VSLAIDAYPL+KH N EY
Sbjct 4924 MQIVDKDGTYYLPYPDPSRILSAGVFVDDIVKTDPVILLERYVSLAIDAYPLSKHDNPEY 4983
Query 5270 ADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGAC 5329
VF + L +++ L+ L +LD +SV L D T+++W+ FY +MY +VLQ+ G C
Sbjct 4984 RRVFTVMLDWVKHLYKTLNQGVLDSFSVTLLEDATAKFWDESFYASMYEQSSVLQSAGLC 5043
Query 5330 VLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYL 5389
V+C+SQT LRCG CIRRP LC KC YDHV+STSHK +L++ PYVC + GC V+DVT+LYL
Sbjct 5044 VVCSSQTVLRCGDCIRRPMLCTKCAYDHVVSTSHKFILAITPYVCCSSGCGVSDVTKLYL 5103
Query 5390 GGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANT 5449
GG+SY+C HKP +SFPLC++G VFGLYKN+ GS +V DFN +AT DWT+ DY LAN
Sbjct 5104 GGLSYWCVDHKPRLSFPLCSSGNVFGLYKNSATGSPDVDDFNTLATSDWTDVKDYKLAND 5163
Query 5450 CTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGY 5509
+ L+LFAAET+KA EE+ K SY AT+ EV+ +EL L WEVGKPRPPL+RN VFT Y
Sbjct 5164 VKDSLRLFAAETIKAKEESVKSSYACATIHEVVGPKELVLKWEVGKPRPPLSRNSVFTCY 5223
Query 5510 RVTKNSKVQIGEYTFEKGDY-GDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQE 5568
+TKN+K Q+GE+TFEK DY DAV Y+ T T KL G FVLTSH V PL APT++ QE
Sbjct 5224 HITKNTKFQVGEFTFEKLDYDNDAVSYKSTATTKLVPGMVFVLTSHNVQPLRAPTIINQE 5283
Query 5569 HYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARI 5628
Y + L P NI +++S+ + YQ +G QK +T+QGPPG+GKSH IGL LY+P ARI
Sbjct 5284 RYSTLHKLRPAFNIHEDYSNLIPYYQLIGKQKLTTIQGPPGSGKSHCVIGLGLYFPGARI 5343
Query 5629 VYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALP 5688
V+TACSHAAVD+LC KA D+CSRIIP +AR+EC+D FK N+T QY+F TVNALP
Sbjct 5344 VFTACSHAAVDSLCVKAATAYSSDRCSRIIPQKARIECYDGFKSNNTSAQYLFSTVNALP 5403
Query 5689 ETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNS 5748
E ADI V DE+SM TNYDLSV+N R+ +H VY+GDP QLPAPR ++T+G L PE +N
Sbjct 5404 EVNADICVVDEVSMCTNYDLSVINQRVNYRHIVYVGDPQQLPAPRVMITRGVLVPEDYNV 5463
Query 5749 VCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDV 5808
V R M + PD+FL C RCPAEIV+TVS +VY+N+ K +S +CFK++ +G + D
Sbjct 5464 VTRRMCVLKPDIFLHKCYRCPAEIVNTVSEMVYENQFVPVKSESKECFKIYCRGNVQVDN 5523
Query 5809 SSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYV 5868
S+INR Q+ VVR FL +NP W KAVFISPYNSQN VA ++LGL QTVDSSQGSEYDYV
Sbjct 5524 GSSINRRQLEVVRMFLAKNPKWAKAVFISPYNSQNYVAGRVLGLQIQTVDSSQGSEYDYV 5583
Query 5869 IFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAEN 5928
I+TQT++TAH+ NVNRFNVAITRAK GILCIM DR+L+D L+F L++ + LQ +
Sbjct 5584 IYTQTSDTAHASNVNRFNVAITRAKKGILCIMCDRELFDILKFYELKL-----SDLQVGD 5638
Query 5929 VTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMN 5988
GLFKDC K L P+ APT +S+ FKT+ G+ + Y +IS MGF+ +
Sbjct 5639 GCGLFKDCYKGEDNLPPSHAPTFMSLSDNFKTDKDLAVQIGVNGPVKYEHVISFMGFRFD 5698
Query 5989 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 6048
V +F TR+ A+R+ R W+GFDVEG H VGTN+PLQLGFS GV+ V P G
Sbjct 5699 INVPNQHTLFCTRDFAMRNARGWLGFDVEGAHVIGSNVGTNVPLQLGFSNGVDFVVRPEG 5758
Query 6049 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 6108
V T V A+ PPGDQF HL+PL+ KG PW+V+R +IVQM SD L NLSD ++F
Sbjct 5759 CVSTEVGDVIQPVRARAPPGDQFTHLLPLLRKGQPWSVIRRRIVQMCSDYLANLSDTLIF 5818
Query 6109 VLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 6168
VLW+ G ELT+M+YFVK+GP +TC C +RATC+++ + T++C+ H++G DY+YN + ID
Sbjct 5819 VLWSGGLELTTMRYFVKLGPVQTC-DCGKRATCYNSTNHTFSCFRHALGSDYIYNCYCID 5877
Query 6169 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 6228
+QQWG+TG+L NH C +H N HVAS DA MTRCLA+H+CFVK VDW+I YP I +E
Sbjct 5878 IQQWGYTGSLSMNHHEVCNIHRNEHVASGDAAMTRCLAIHDCFVKNVDWSITYPFIANEQ 5937
Query 6229 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 6288
IN + R VQ V++A L +HD+GNPK I+CV D W YD P + +
Sbjct 5938 AINKSGRLVQSHVMRAVLKLYNPKAIHDVGNPKGIRCV-VTDASWYCYDKNPTNTNVKML 5996
Query 6289 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 6348
E Y Y TH DG+CLFWNCNVD YP S+VCRFDTR+ S LNL GC+GGSLYVN
Sbjct 5997 E---YDYITHGQ--LDGLCLFWNCNVDMYPEFSVVCRFDTRMRSTLNLEGCNGGSLYVNN 6051
Query 6349 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 6408
HAFHTPA+DK AF LK +PFF+Y DS CE ++ ++YVPL+++ CITRCN+GGAV
Sbjct 6052 HAFHTPAYDKRAFAKLKAMPFFFYDDSECE----KLQDAVNYVPLRASNCITRCNVGGAV 6107
Query 6409 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF--TRLQSLENVAFNVVNKGH 6466
C H Y Y+ AYN +AGF++WV FD +NLW TF + +Q LEN+A+NVV KG
Sbjct 6108 CSKHCALYHNYVMAYNTFTTAGFTIWVPNSFDMFNLWQTFKNSNVQGLENIAYNVVKKGS 6167
Query 6467 FDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNN 6526
F G +GE+PV+++N+ V + D +F N T+LP NVAFEL+AKR + P + IL N
Sbjct 6168 FVGVEGELPVAVVNDKVMVRDGVSDNVVFVNNTSLPTNVAFELYAKRKVGLTPPLTILKN 6227
Query 6527 LGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLF 6586
LGV + V+WDY+ P T VC TD + FD V G + F
Sbjct 6228 LGVVCTSKCVLWDYEASRPLTTFTKDVCKYTDFD--------GDVCTLFDNSVPGAFERF 6279
Query 6587 RNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI-GEAVKTQFNYYKKVDGVVQQLPETY 6645
+N VLI+ +VK L ++ LNGV + E + Y + DG + P+ Y
Sbjct 6280 TVTKNAVLISLTAVKKLT-AIKLTYGYLNGVPVFTHEDKPFTWYIYTRKDGAFVEYPDGY 6338
Query 6646 FTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIG 6705
FTQ R + +F+PRS ME DFL + M FI +Y LE Y FEH+V+GD S + LGGLHLLI
Sbjct 6339 FTQGRVISDFQPRSNMEEDFLNMDMGLFISKYGLEDYGFEHVVFGDVSKTTLGGLHLLIS 6398
Query 6706 LAKRFKESPFELEDFI-PMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLS 6764
+ K ++EDF+ DST+K+ +T SSK VC+ +DLLLDDFV I+KS DLS
Sbjct 6399 QIRLSKIGVLKVEDFVSSSDSTLKSCTVTYVDNPSSKMVCTYVDLLLDDFVNILKSVDLS 6458
Query 6765 VVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCD 6824
VVSKV +V ID +MLWCKD V+TFYP+LQS++ W+ G +MP++YK+QRM LE C+
Sbjct 6459 VVSKVHEVVIDCKVWRWMLWCKDHKVQTFYPQLQSAE-WKCGYSMPSIYKIQRMCLEPCN 6517
Query 6825 LQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLR 6884
L NYG LP GIM NV KYTQLCQYLN+ T+ VP++MRV+H GAGSDKGVAPGTAVLR
Sbjct 6518 LYNYGSGLKLPDGIMFNVVKYTQLCQYLNSTTMCVPHHMRVLHLGAGSDKGVAPGTAVLR 6577
Query 6885 QWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSK 6944
+WLP ++VD+D+ND+VSDAD + GDCA+++ +K+DL+ISDMYD +TK+ +N SK
Sbjct 6578 RWLPLDAVIVDNDVNDYVSDADFSYTGDCASMYLTDKFDLVISDMYDGRTKSCDGDNVSK 6637
Query 6945 EGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFL 7004
EGFF YI G I +KLALGG+VAIKITE SWN LY+L+ F +WT F T+VN SSSEAFL
Sbjct 6638 EGFFPYINGVITEKLALGGTVAIKITEFSWNKKLYELIQKFEYWTLFCTSVNTSSSEAFL 6697
Query 7005 IGCNYLGK--PREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE 7062
IG ++LG IDG +MHANYIFWRN+ + +S S+ D+SKF K + T V++LK+
Sbjct 6698 IGVHFLGDFSTNAIIDGNIMHANYIFWRNSTIMTMSYNSVLDLSKFSCKHKATVVVNLKD 6757
Query 7063 GQINDMILSLLSKGRLIIRENNRVVISSDVLVNN 7096
+ D++L LL G+L+IR N V S+ LVN+
Sbjct 6758 SSVTDLVLGLLKNGKLLIRNNGVVCGFSNHLVNS 6791
Score = 216 bits (549), Expect = 1e-53, Method: Composition-based stats.
Identities = 84/363 (23%), Positives = 129/363 (36%), Gaps = 36/363 (10%)
Query 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
+L E + ++V T D + HT + S TYGQQ G ++ VT +KP + K V
Sbjct 1634 TLFEAKPVQVVVTQDQRSFHTVELSTSQTYGQQLGDCVVEDKKVTNLKPVSKD--KVVSV 1691
Query 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTK-KWKYPQVNGLTSIKWADNNCYLATA 1679
+PN V+ ++Y D L+HT + VNG ++ +DNNC++
Sbjct 1692 VPN-----VDWDKHYGFVDAGI----FHTLDHTMFVFDNNVVNGKRVLRTSDNNCWINAV 1742
Query 1680 LLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHA 1739
L LQ KF P LQ + G+ A F + GE D T++ + +
Sbjct 1743 CLQLQFANAKFKPKGLQQLWESYCTGDVAMFVHWLYWITGVEKGEPSDAENTLNIISRFL 1802
Query 1740 NLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQ 1799
+L TC +T + V + ++ G C G +V
Sbjct 1803 KPQGSVEMLRATSTTCDGTCSTKRVVSTPVVNASVLKVGLDDG---NCVHGLPLVDRVVS 1859
Query 1800 QESPFVMMSA--PP------AQYELKHGTFTCASEYT-GNYQCGHYKHITSKETLYCIDG 1850
++ + P + L G + GHY + KE DG
Sbjct 1860 VNGTVIITNVGDTPGKPVVATENLLLDGVSYT--VFQDSTTGVGHYT-VFDKEAKLMFDG 1916
Query 1851 ALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPK--LDNYYKKDNSYFT 1908
+L P+T V N K V D V E+D LD +FT
Sbjct 1917 DVLKPCDLNVSPVTSVVVCNNK-----KIVVQ--DPVKRVELDASKFLDTMNVASEKFFT 1969
Query 1909 EQP 1911
Sbjct 1970 FGD 1972
Score = 171 bits (434), Expect = 2e-40, Method: Composition-based stats.
Identities = 73/265 (28%), Positives = 108/265 (41%), Gaps = 19/265 (7%)
Query 993 GSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKV 1052
G + TI T+ E+ + +V F Y N+ ++ V
Sbjct 1268 GRHPIKFNTINTLCYKDVDWEVS----NGSCDVKPFLTY----KNIEFYQGELSALL-SV 1318
Query 1053 KPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAK 1112
VVNAAN L HGGG+A AL+ T +QV S+ Y++ NG +KVG ++
Sbjct 1319 NHDFVVNAANEQLSHGGGIAKALDDLTKGELQVLSNQYVSRNGSIKVGSGVLIKCKE--H 1376
Query 1113 HCLHVVGPNVNKGEDIQLLKSAYE-NFNQHEVLLAPLLSAGIFGADPIHSLR---VCVDT 1168
L+VVGP K +LL AY F Q V L PLLS GIF SL CV
Sbjct 1377 SILNVVGPRKGK-HAAELLTKAYTFVFKQKGVPLMPLLSVGIFKVPITESLAAFLACVGD 1435
Query 1169 VRTNVYLAVFDKNL-YDKLVSSFLEMK--SEKQVEQKIAEIPKEEVKPFITESKPSVEQR 1225
+ + L V+SF + V Q++ + E+ P + P R
Sbjct 1436 RVCKCFCYTDKERLAIQNFVTSFQTEQPVEPLPVIQEVKGVQLEKPVPDVKVENPCEPFR 1495
Query 1226 KQDDKKIKACVEEVTTTLEETKFLT 1250
+ D K + +L+ T+ ++
Sbjct 1496 IEGDAKFYDLTPSMVQSLQVTRLVS 1520
Score = 65.1 bits (157), Expect = 3e-08, Method: Composition-based stats.
Identities = 37/190 (19%), Positives = 64/190 (34%), Gaps = 14/190 (7%)
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAA 1708
+ Y GL + + NNC++++AL+ LQ L + +Q AG +
Sbjct 1078 VKPDVFAFSYASYGGLKVLNQSSNNCWVSSALVQLQLTGL-LDSDEMQL----FNAGRVS 1132
Query 1709 NFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAV 1768
G LGDV + L + + S ++ C ++ E
Sbjct 1133 PMVKRCYESQRAIFGSLGDVSACLESLLKDRDGMSITCTIDCGCGP------GVRVYENA 1186
Query 1769 MYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM-SAPPAQYELKHGTFTCASEY 1827
++ T F G + C+ K + Q + + A + CA+ Y
Sbjct 1187 IFRFTPLKTAFPMGRCLICS--KTLMHTITQMKGTGIFCRDATALDVDTLVVKPLCAAVY 1244
Query 1828 TGNYQCGHYK 1837
G GHY
Sbjct 1245 VGAQDGGHYL 1254
Score = 60.5 bits (145), Expect = 8e-07, Method: Composition-based stats.
Identities = 55/380 (14%), Positives = 122/380 (32%), Gaps = 40/380 (11%)
Query 653 STCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTH 712
V + +++ F V F+ + + + + +
Sbjct 750 LNGVVVFVTKKFRKAGALLQKLYNAFLDTVTSFIKVAGVAFKYCATCVPKIVIN------ 803
Query 713 SKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSE 772
G Y + + L +P + + V + LE +
Sbjct 804 --GCYHTVTRLFAK-DLQIPTEDG------VADFNTFNHCVFPVNPTRIETDSLELEEVD 854
Query 773 AVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIE 832
VE + G V ++ T Y + V + F KGG ++ + V
Sbjct 855 FVEPGVDGKLVILDDYSFYS-DGTNYYP--SDGKGVVASCFKKKGGGVVTIS-DEVQVRT 910
Query 833 VQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTP 892
+ V + +E + D+ L + C +GT++ V L+ + + +
Sbjct 911 IDPVYKVRLEYEFE---DETLVKVC---EKAIGTKLK-----VTGDWSNLLETLEKAMDV 959
Query 893 LGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTE 952
+ LD + Y+++DE G L + S +P D E ++F+
Sbjct 960 VRQHLD---VPDYFVYDEEGGTDLNLTIMVSQWPLSSDSE------DDFKAVDDEPNANT 1010
Query 953 DDYQGKPLEFGATSAALQPEEEQEE-DWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQ 1011
D+ E A + +Q + Q+E + + D + + + + + + +
Sbjct 1011 DETVDTFAEDVAETQNVQQDVTQDEVEAVCDLVVKATEEGPIEHEELSEDQKEVQQALAF 1070
Query 1012 LEMELTPVVQTIEVNSFSGY 1031
+E + V + S++ Y
Sbjct 1071 IEDKPVVVKPDVFAFSYASY 1090
Score = 52.0 bits (123), Expect = 3e-04, Method: Composition-based stats.
Identities = 40/209 (19%), Positives = 64/209 (31%), Gaps = 39/209 (19%)
Query 172 ELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCC 231
+L+ GG VD CG DG P+ + G + +D+ +
Sbjct 102 DLVFGRCGGTTIP-VDQFMCGADGAPV-------IQEGDWTF-----MDYFQ-DSNQFTL 147
Query 232 REHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQ-PRVEK 290
+ AW +R Y Q I+ V + +KT + P+V K
Sbjct 148 NGITYVKAWDVDRKPNDYAKQNVTCIRRITYITDH-----RHVLADGTTMKTARHPKVNK 202
Query 291 KKLDG-------------FMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFV 337
+ FMG + V + L+ C+ CG + W GD+
Sbjct 203 SVVLDSPFDQIYKEVGSPFMGNGSTF--VEMLKDPAFFH--ALITCE-CGRSEWTVGDW- 256
Query 338 KATCEFCGTENLTKEGATTCGYLPQNAVV 366
K C T +P V+
Sbjct 257 KGYNSLCCNIKCKPITIVTPKAVPGAVVI 285
>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781
Score = 6838 bits (17740), Expect = 0.0, Method: Composition-based stats.
Identities = 2288/5142 (44%), Positives = 3149/5142 (61%), Gaps = 207/5142 (4%)
Query 2018 PVETSNSFDVLK---SEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLE----------- 2063
P ++ N+ ++L D S+ VV P + VL+
Sbjct 1780 PSDSENALNMLSKYIVPAGSVTIERVTHDGCCCSKRVVTAPVVNASVLKLGVEDGLCPHG 1839
Query 2064 --CNVKTTEVVGDIILKPANNSLKITEEVGHTDL-MAAYVDNSSLTI------------- 2107
K V G I+ + + + ++DN + +
Sbjct 1840 LNYIGKVVVVKGTTIVVNVGKPVVAPSHLFLKGVSYTTFLDNGNGVVGHYTVFDHGTGMV 1899
Query 2108 -----KKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVT--RC 2160
P +L+ + + A V P A L+ + + +
Sbjct 1900 HDGDAFVPGDLNVSPVTNVVVSEQTAVVIKDPVKKAELDATKLLDTMNYASERFFSFGDF 1959
Query 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
++R Y ++L R + ++ A +P KS+ ++ +A + K
Sbjct 1960 MSRNLITVFLYILSILGLCFRAFRKRDVKVLAGVPQRTGIILRKSM-RYNAKALGVFFKL 2018
Query 2221 PNFSKLINIIIWFLLLS-VCLG-SLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTI 2278
+ WF +L LG +Y+ + + + +G P C GY NS+
Sbjct 2019 K--------LYWFKVLGKFSLGIYALYALLFMTIRFTPIGSP-VCDDVVAGYANSS-FDK 2068
Query 2279 ATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKW-DLTAFGLVAEWFLAYILFTRF 2337
YC S+ C VCL G L + + + + ++ F +A + ++ +
Sbjct 2069 NEYC-NSVICKVCLYGYQELSDFSHTQVVWQHLRDPLIGNVMPFFYLAFLAIFGGVYVKA 2127
Query 2338 FYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY 2397
+ + + + + I +Q+ P + F V
Sbjct 2128 ITLYFIFQYLNSLGVFLG---------LQQSIWFLQLVPFDVFGDEIVVFFIVTRVLMFI 2178
Query 2398 VHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDT 2457
HV GC+ ++C+ C K R RV TI G +SFYV+ANGG FCK HN+ C+NCD+
Sbjct 2179 KHVCLGCDKASCVACSKSARLKRVPVQTIFQGTSKSFYVHANGGSKFCKKHNFFCLNCDS 2238
Query 2458 FCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHS 2517
+ G TFI+D +A ++ K + PT ++ ++D V NG +LY K +
Sbjct 2239 YGPGCTFINDVIATEVGNVVKLNVQPTGPATILIDKVEFSNGFYYLYSGDTFWKYNFDIT 2298
Query 2518 LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALV 2577
S + + L+ S+ + IVF+ + K+A VY+SQ++C+P+ L+D AL+
Sbjct 2299 DSKYTCKEALK----NCSIITDFIVFNNNG-SNVNQVKNACVYFSQMLCKPVKLVDSALL 2353
Query 2578 SDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNV-LSTFISA 2636
+ + S + + A+V+ S++F + + + + D+V L TF +A
Sbjct 2354 ASL--SVDFGASLHSAFVSVLSNSFGKDLSSCNDM-----QDCKSTLGFDDVPLDTFNAA 2406
Query 2637 ARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTP-RDLGACIDCS 2695
+ +H+ D+ +T S NN+ +Y K E P D+ C+
Sbjct 2407 VAE------------------AHRYDVLLTDMSFNNFTTSYAKPEEKFPVHDIATCMRVG 2448
Query 2696 ARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVT 2755
A+ +N V +I ++W V+DF++LSE+ RK I K + F LT R + T
Sbjct 2449 AKIVNHNVLVKDSIPVVWLVRDFIALSEETRKYIIRTTKVKGITFMLTFNDCRMHTTIPT 2508
Query 2756 TKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGG 2815
IA K G + ++ K + LF+ A F+ ++ + ++ + S +K I+ G
Sbjct 2509 VCIANKKGAGLPSFSKVKKFFWFLCLFIVAAFFALSFLDFSTQVSSDSD--YDFKYIESG 2566
Query 2816 VTRDIASTDTCFANKHADFDTWFSQRGGS-YTNDKACPLIAAVITREVGFVVPGLPGTIL 2874
+ + +C N +FD W + G N+ +CP++ V + VPG+P +
Sbjct 2567 QLKTFDNPLSCVHNVFINFDQWHDAKFGFTPVNNPSCPIVVGV--SDEARTVPGIPAGVY 2624
Query 2875 RTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCY 2934
G L F +C+ S + + AC+ + CT G V YCY
Sbjct 2625 LA--GKTLVFAINTIFGTSGLCFDASGVAD-----KGACIFNSACTTLSGLGGTAV-YCY 2676
Query 2935 DTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCERSE 2993
++EG+ Y L P + Y ++DG+ + P G +R + T YCR G C +S
Sbjct 2677 KNGLVEGAKLYSELAPHSYYKMVDGNAVSLPEIISRGFGIRTIRTKAMTYCRVGQCVQSA 2736
Query 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
GVC +V N + S CG LL N+ + + + +S I+ I+
Sbjct 2737 EGVCFGADRFFVYNAE---SGSDFVCGTGLFTLLMNVISVFSKTVPVTVLSGQILFNCII 2793
Query 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
A V + + F +F+R FG+ S V L++ +T + + Y L
Sbjct 2794 AFVAVAVCFLFTKFKRMFGDMSVGVFTVGACTLLNNVSYIVTQ-----NTLGMLGYATLY 2848
Query 3114 FYLTNDVS--FLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFN 3168
F T V ++ H+ +++ + + P+W+ + Y + + F N K +V +F
Sbjct 2849 FLCTKGVRYMWIWHLGFLISYILIAPWWVLMVY----AFSAIFEFMPNLFKLKVSTQLFE 2904
Query 3169 GVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYR 3227
G F +FE AA TF+L+ Y +L + + + +Y + YNKYKY+SG+ YR
Sbjct 2905 GDKFVGSFENAAAGTFVLDMHAYERLANSI--STEKLRQYASTYNKYKYYSGSASEADYR 2962
Query 3228 EAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGT 3287
A HLAKA+ D++++ +D LY PP S S LQ+G RKMA PSG VE C+V+V G
Sbjct 2963 LACFAHLAKAMMDYASNHNDTLYTPPTVSYNST-LQAGLRKMAQPSGVVEKCIVRVCYGN 3021
Query 3288 TTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQN 3347
LNGLWL D+V CPRHVI +S +Y+ L HNF + +GNV L V+ +M+
Sbjct 3022 MALNGLWLGDIVMCPRHVIASSTTST-IDYDYALSVLRLHNFSISSGNVFLGVVSATMRG 3080
Query 3348 CVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGS 3407
+L++KV+ N TPKY + ++PG++F++LACY+G+ +GVY MR N+TI+GSF+NG+
Sbjct 3081 ALLQIKVNQNNVHTPKYTYRTVRPGESFNILACYDGAAAGVYGVNMRSNYTIRGSFINGA 3140
Query 3408 CGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNV 3467
CGS G+NI+ V FCY+H +EL +G H G+DL+G YG + D+ T Q G + T NV
Sbjct 3141 CGSPGYNINNGTVEFCYLHQLELGSGCHVGSDLDGVMYGGYEDQPTLQVEGASSLFTENV 3200
Query 3468 LAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDM 3527
LA+LYAA+ING W+L+ ++ FN A+ + + D L+A+TG+ V +
Sbjct 3201 LAFLYAALINGSTWWLSSSRIAVDRFNEWAVHNGMTTVG--NTDCFSILAAKTGVDVQRL 3258
Query 3528 CASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSA-VKRTIKGTHHWLLLT 3586
AS++ L +N G+ ILG L DEFT +VVRQ GV Q V R + +
Sbjct 3259 LASIQSLHKN-FGGKQILGHTSLTDEFTTGEVVRQMYGVNLQGGYVSRACRN------VL 3311
Query 3587 ILTSLLVLVQS--TQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSL 3644
++ S L S ++ FF++ P + +S+ M +KHK F +FL+P+L
Sbjct 3312 LVGSFLTFFWSELVSYTKFFWVNPGYVTPMFACLSLLSSLLMFTLKHKTLFFQVFLIPAL 3371
Query 3645 ATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILM---TARTVY 3701
+ N+ + + + SL GF + V V+ IL T R
Sbjct 3372 IVTSCINLAFDVEVY--NYLAEHFDYHVSLMGFNAQGLVNIFVCFVVTILHGTYTWRFFN 3429
Query 3702 DDGARRVWTLMNVLTLVYKVYYGNA-LDQAISMWALIISVTSNYSGVVTTVMFLARGIVF 3760
A V ++ +LT Y +Y + L A++++A SVT N V V + + V+
Sbjct 3430 -TPASSVTYVVALLTAAYNYFYASDILSCAMTLFA---SVTGN--WFVGAVCY--KVAVY 3481
Query 3761 MCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEF 3820
M + + P F ++ +M Y LGYF C++G+ NR+F++++GVYDY VS EF
Sbjct 3482 MALRF-PTFVAIFGDIKSVMFCYLVLGYFTCCFYGILYWFNRFFKVSVGVYDYTVSAAEF 3540
Query 3821 RYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLR 3880
+YM + GL P ++D+ L+ KL+G+GG+ IK+++VQSK++D+KC++VVLL L +
Sbjct 3541 KYMVANGLRAPTGTLDSLLLSAKLIGIGGERNIKISSVQSKLTDIKCSNVVLLGCLSSMN 3600
Query 3881 VESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRAT 3940
V ++S WA CV LHN I L D +A E +++LL+ LS A ++ L E ++ +
Sbjct 3601 VSANSTEWAYCVDLHNKINLCNDPEKAQEMLLALLAFFLSKNSAFGLDDLLESYFNDNSM 3660
Query 3941 LQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRK 4000
LQ++AS + LPSY + A++ YE AV NG ++K+L+ ++NVAKSEFDR+A+ QRK
Sbjct 3661 LQSVASTYVGLPSYVIYENARQQYEDAVNNGSPPQLVKQLRHAMNVAKSEFDREASTQRK 3720
Query 4001 LEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLN 4060
L++MA+QA QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I+N A+DG VPL+
Sbjct 3721 LDRMAEQAAAQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNLAKDGVVPLS 3780
Query 4061 IIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSP 4120
+IP +A KL +V D ++Y YA +W I + D D K+V + E++ N+
Sbjct 3781 VIPAVSATKLNIVTSDIDSYNRIQREGCVHYAGTIWNIIDIKDNDGKVVHVKEVTAQNAE 3840
Query 4121 NLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRF 4180
+L+WPL++ R VKLQNNE+ P L+Q S A A YN G F
Sbjct 3841 SLSWPLVLGCER---IVKLQNNEIIPGKLKQRSIKAEGDGIV---GEGKALYNNEGGRTF 3894
Query 4181 VLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRG 4240
+ A +SD DL+ ++ G TI ELEPP +F+ D+P G ++KYLYF++ LN L RG
Sbjct 3895 MYAFISDKPDLRVVKWEFDGGCNTI--ELEPPRKFLVDSPNGAQIKYLYFVRNLNTLRRG 3952
Query 4241 MVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCT 4300
VLG + ATVRLQAG TE NS++L+ CAFAVD AK Y D + SG +P+ NCVKML
Sbjct 3953 AVLGYIGATVRLQAGKQTEQAINSSLLTLCAFAVDPAKTYIDAVKSGHKPVGNCVKMLAN 4012
Query 4301 HTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDP 4360
+G GQA+T EA+ +Q+S+GGAS CLYCR H++HP+ GFC LKGKYVQ+P DP
Sbjct 4013 GSGNGQAVTNGVEASTNQDSYGGASVCLYCRAHVEHPSMDGFCRLKGKYVQVPLGTV-DP 4071
Query 4361 VGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTST 4420
+ F L+N VC VCG W GC+CD+ + + ++LNRV G SAARL PC GT T
Sbjct 4072 IRFVLENDVCKVCGCWLSNGCTCDR----SIMQSTDMAYLNRVRGSSAARLEPC-NGTDT 4126
Query 4421 DVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYN 4480
VYRAFDIYN VA KFLK NC R + D+ D+++VVKR T S +HE++IY+
Sbjct 4127 QHVYRAFDIYNKDVACLGKFLKVNCVRLKNLDKH----DAFYVVKRCTKSAMEHEQSIYS 4182
Query 4481 LLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVT 4540
L+ C A+A+HDFF ++ + ++ R+ LT+YTM DL YALR+FDE NCD LK IL+
Sbjct 4183 RLEKCGAIAEHDFFTWKDGRAIYGNVCRKDLTEYTMMDLCYALRNFDENNCDVLKSILIK 4242
Query 4541 YNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLD 4600
C++ YFN K W+D VEN DI RVYA LG V +A+LK V+FCDAM GIVGV+TLD
Sbjct 4243 VGACEESYFNNKVWFDPVENEDIHRVYALLGTIVARAMLKCVKFCDAMVEQGIVGVVTLD 4302
Query 4601 NQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDL-TKPYIK 4659
NQDLNG++YDFGDF + G GVP+ SYYS +MP++ +T L +E V +D+ + +
Sbjct 4303 NQDLNGDFYDFGDFTCSIKGMGVPICTSYYSYMMPVMGMTNCLASECFVKSDIFGEDFKS 4362
Query 4660 WDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFG 4719
+DLL+YDFTE + LF++YFKYW YHPNCV+C D++CI+HCANFN LFST P T+FG
Sbjct 4363 YDLLEYDFTEHKTALFNKYFKYWGLQYHPNCVDCSDEQCIVHCANFNTLFSTTIPITAFG 4422
Query 4720 PLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNL 4779
PL RK ++DGVP V + GYHF++LG+V N D+NLHSSRLS ELL + +DPA+ AS
Sbjct 4423 PLCRKCWIDGVPLVTTAGYHFKQLGIVWNNDLNLHSSRLSINELLQFCSDPALLIASSPA 4482
Query 4780 LLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGN 4839
L+D+RT CFSVAAL + QTVKPG+FNK+FYDF + +GFF EGS + LKHFFFAQ +
Sbjct 4483 LVDQRTVCFSVAALGTGMTNQTVKPGHFNKEFYDFLLEQGFFSEGSELTLKHFFFAQKVD 4542
Query 4840 AAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFN 4899
AA+ D+DYYRYN PT+ DI Q V ++V +YFD Y+GGCI A +V+V NL+KSAG+P N
Sbjct 4543 AAVKDFDYYRYNRPTVLDICQARVVYQIVQRYFDIYEGGCITAKEVVVTNLNKSAGYPLN 4602
Query 4900 KWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMT 4959
K+GKA LYY+S+SYE+QD L+AYTKRN++PT+TQ+NLKYAIS K RARTV GVS+ STMT
Sbjct 4603 KFGKAGLYYESLSYEEQDELYAYTKRNILPTMTQLNLKYAISGKERARTVGGVSLLSTMT 4662
Query 4960 NRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMP 5019
RQ+HQK LKSI TRGA+VVIGT+KFYGGW NMLK + VENP LMGWDYPKCDRA+P
Sbjct 4663 TRQYHQKHLKSIVNTRGASVVIGTTKFYGGWDNMLKNLIDGVENPCLMGWDYPKCDRALP 4722
Query 5020 NMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATT 5079
NM+R++++++L KHTTCCS + RF+RL NE AQVL+E+V G Y+KPGGT+SGDATT
Sbjct 4723 NMIRMISAMILGSKHTTCCSSTDRFFRLCNELAQVLTEVVYSNGGFYLKPGGTTSGDATT 4782
Query 5080 AYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYA 5139
AYANSVFNI QAV+ANVN LLS D N + V+ LQ +LYEC YR+ VD FV E+Y
Sbjct 4783 AYANSVFNIFQAVSANVNKLLSVDSNVCHNLEVKQLQRKLYECCYRSTIVDDQFVVEYYG 4842
Query 5140 YLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTK 5199
YLRKHFSMMILSDD VVC+N+ YAS G VA + FK+VLYYQNNVFMS +KCW E D+ K
Sbjct 4843 YLRKHFSMMILSDDGVVCYNNDYASLGYVADLNAFKAVLYYQNNVFMSASKCWIEPDINK 4902
Query 5200 GPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAY 5259
GPHEFCSQHTM + + YLPYPDPSRIL AG FVDD+VKTD +++ER+VSLAIDAY
Sbjct 4903 GPHEFCSQHTMQIVDKEGTYYLPYPDPSRILSAGVFVDDVVKTDAVVLLERYVSLAIDAY 4962
Query 5260 PLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTP 5319
PL+KH N EY VF++ L +++ L+ L +L+ +SV L D+T+++W+ FY MY
Sbjct 4963 PLSKHENPEYKKVFYVLLDWVKHLYKTLNAGVLESFSVTLLEDSTAKFWDESFYANMYEK 5022
Query 5320 HTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGC 5379
VLQ+ G CV+C SQT LRCG C+RRP LC KC YDHVI T+HK +L++ PYVC A C
Sbjct 5023 SAVLQSAGLCVVCGSQTVLRCGDCLRRPMLCTKCAYDHVIGTTHKFILAITPYVCCASDC 5082
Query 5380 DVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWT 5439
V DVT+LYLGG+SY+C HKP ++FPLC+ G VFGLYKN+ GS +V DFN IAT DWT
Sbjct 5083 GVNDVTKLYLGGLSYWCHEHKPRLAFPLCSAGNVFGLYKNSATGSPDVEDFNRIATSDWT 5142
Query 5440 NAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPP 5499
+ DY LAN + L+LFAAET+KA EE+ K SY AT+ EV+ +EL L WEVG+P+PP
Sbjct 5143 DVSDYRLANDVKDSLRLFAAETIKAKEESVKSSYACATLHEVVGPKELLLKWEVGRPKPP 5202
Query 5500 LNRNYVFTGYRVTKNSKVQIGEYTFEKGDY-GDAVVYRGTTTYKLNVGDYFVLTSHTVMP 5558
LNRN VFT Y +TKN+K QIGE+ FEK +Y DAV Y+ T T KL G FVLTSH V P
Sbjct 5203 LNRNSVFTCYHITKNTKFQIGEFVFEKAEYDNDAVTYKTTATTKLVPGMVFVLTSHNVQP 5262
Query 5559 LSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIG 5618
L APT+ QE Y I L+P NI + +SS V YQ +G QK +T+QGPPG+GKSH IG
Sbjct 5263 LRAPTIANQERYSTIHKLHPAFNIPEAYSSLVPYYQLIGKQKITTIQGPPGSGKSHCVIG 5322
Query 5619 LALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQ 5678
L LYYP ARIV+TACSHAAVD+LC KA DKCSRIIP RARVEC+D FK N+T Q
Sbjct 5323 LGLYYPGARIVFTACSHAAVDSLCVKASTAYSNDKCSRIIPQRARVECYDGFKSNNTSAQ 5382
Query 5679 YVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTK 5738
Y+F TVNALPE ADIVV DE+SM TNYDLSV+N R+ +H VY+GDP QLPAPR ++++
Sbjct 5383 YLFSTVNALPECNADIVVVDEVSMCTNYDLSVINQRISYRHVVYVGDPQQLPAPRVMISR 5442
Query 5739 GTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKM 5798
GTLEP+ +N V + M + PD+FL C RCPAEIV TVS +VY+N+ S QCFK+
Sbjct 5443 GTLEPKDYNVVTQRMCALKPDVFLHKCYRCPAEIVRTVSEMVYENQFIPVHPDSKQCFKI 5502
Query 5799 FYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVD 5858
F KG + D S+INR Q+ VVR FL +NP W KAVFISPYNSQN VAS++LGL QTVD
Sbjct 5503 FCKGNVQVDNGSSINRRQLDVVRMFLAKNPRWSKAVFISPYNSQNYVASRLLGLQIQTVD 5562
Query 5859 SSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPR 5918
SSQGSEYDYVI+ QT++TAH+ NVNRFNVAITRAK GILCIM DR L+D L+F L++
Sbjct 5563 SSQGSEYDYVIYAQTSDTAHASNVNRFNVAITRAKKGILCIMCDRSLFDLLKFFELKL-- 5620
Query 5919 RNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRR 5978
+ LQA GLFKDCS+ L P+ A T +S+ FKT+ G+ + Y
Sbjct 5621 ---SDLQANEGCGLFKDCSRGDDLLPPSHANTFMSLADNFKTDQYLAVQIGVNGPIKYEH 5677
Query 5979 LISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFST 6038
+IS MGF+ + + + +F TR+ A+R+VR W+GFDVEG H VGTN+PLQLGFS
Sbjct 5678 VISFMGFRFDINIPNHHTLFCTRDFAMRNVRGWLGFDVEGAHVVGSNVGTNVPLQLGFSN 5737
Query 6039 GVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDT 6098
GV+ V P G V T + V A+ PPG+QF HL+PL+ +G PW+VVR +IVQM SD
Sbjct 5738 GVDFVVRPEGCVVTESGDYIKPVRARAPPGEQFAHLLPLLKRGQPWDVVRKRIVQMCSDY 5797
Query 6099 LKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGF 6158
L NLSD ++FVLWA G ELT+M+YFVKIGP ++C C + ATC+++A TY C+ H++G
Sbjct 5798 LANLSDILIFVLWAGGLELTTMRYFVKIGPSKSC-DCGKVATCYNSALHTYCCFKHALGC 5856
Query 6159 DYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWT 6218
DY+YNP+ ID+QQWG+ G+L NH +C VH N HVAS DAIMTRCLA+H+CFVK VDW+
Sbjct 5857 DYLYNPYCIDIQQWGYKGSLSLNHHEHCNVHRNEHVASGDAIMTRCLAIHDCFVKNVDWS 5916
Query 6219 IEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDA 6278
I YP IG+E IN + R VQ +++ L ++DIGNPK I+C D +W +D
Sbjct 5917 ITYPFIGNEAVINKSGRIVQSHTMRSVLKLYNPKAIYDIGNPKGIRCA-VTDAKWFCFDK 5975
Query 6279 QPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPG 6338
P + +E Y Y TH DG+CLFWNCNVD YP S+VCRFDTR S LNL G
Sbjct 5976 NPTNSNVKTLE---YDYITHGQ--FDGLCLFWNCNVDMYPEFSVVCRFDTRCRSPLNLEG 6030
Query 6339 CDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATC 6398
C+GGSLYVN HAFHTPAFDK AF LK +PFF+Y D+ C+ ++ I+YVPL+++ C
Sbjct 6031 CNGGSLYVNNHAFHTPAFDKRAFAKLKPMPFFFYDDTECD----KLQDSINYVPLRASNC 6086
Query 6399 ITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFT-RLQSLENV 6457
IT+CN+GGAVC H Y Y++AYN SAGF++WV FDTYNLW TF+ LQ LEN+
Sbjct 6087 ITKCNVGGAVCSKHCAMYHSYVNAYNTFTSAGFTIWVPTSFDTYNLWQTFSNNLQGLENI 6146
Query 6458 AFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKP 6517
AFNV+ KG F G +GE+PV+++N+ V + VD +F NKT+LP NVAFEL+AKR +
Sbjct 6147 AFNVLKKGSFVGDEGELPVAVVNDKVLVRDGTVDTLVFTNKTSLPTNVAFELYAKRKVGL 6206
Query 6518 VPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDG 6577
P + IL NLGV + VIWDY+ + P T VC TD + FD
Sbjct 6207 TPPITILRNLGVVCTSKCVIWDYEAERPLTTFTKDVCKYTDFE--------GDVCTLFDN 6258
Query 6578 RVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL-IGEAVKTQFNYYKKVDG 6636
+ G ++ F +N VL++ +VK L + LNGV + E + Y + +G
Sbjct 6259 SIVGSLERFSMTQNAVLMSLTAVKKLT-GIKLTYGYLNGVPVNTHEDKPFTWYIYTRKNG 6317
Query 6637 VVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQ 6696
+ P+ YFTQ R +F PRS ME DFL + M FI +Y LE Y FEH+VYGD S +
Sbjct 6318 KFEDYPDGYFTQGRTTADFSPRSDMEKDFLSMDMGLFINKYGLEDYGFEHVVYGDVSKTT 6377
Query 6697 LGGLHLLIGLAKRFKESPFELEDFIPM-DSTVKNYFITDAQTGSSKCVCSVIDLLLDDFV 6755
LGGLHLLI + ++++F+ DST+K+ +T A SSK VC+ +DLLLDDFV
Sbjct 6378 LGGLHLLISQVRLACMGVLKIDEFVSSNDSTLKSCTVTYADNPSSKMVCTYMDLLLDDFV 6437
Query 6756 EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKM 6815
I+KS DLSVVSKV +V +D +MLWCKD ++TFYP+LQ+S+ W+ G +MP++YK+
Sbjct 6438 SILKSLDLSVVSKVHEVMVDCKMWRWMLWCKDHKLQTFYPQLQASE-WKCGYSMPSIYKI 6496
Query 6816 QRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKG 6875
QRM LE C+L NYG LP GIM NV KYTQLCQYLN+ T+ VP++MRV+H GAGSDKG
Sbjct 6497 QRMCLEPCNLYNYGAGVKLPDGIMFNVVKYTQLCQYLNSTTMCVPHHMRVLHLGAGSDKG 6556
Query 6876 VAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTK 6935
VAPGTAVLR+WLP ++VD+D D+VSDAD ++ GDC+T++ ++K+DL+ISDMYD K K
Sbjct 6557 VAPGTAVLRRWLPLDAIIVDNDSVDYVSDADYSVTGDCSTLYLSDKFDLVISDMYDGKIK 6616
Query 6936 NVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNV 6995
+ EN SKEGFF YI G I +KLALGG+VAIK+TE SWN LY+L+ F +WT F T+V
Sbjct 6617 SCDGENVSKEGFFPYINGVITEKLALGGTVAIKVTEFSWNKKLYELIQKFEYWTMFCTSV 6676
Query 6996 NASSSEAFLIGCNYLGK--PREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLR 7053
N SSSEAFLIG +YLG IDG MHANYIFWRN+ + +S S+ D+SKF K +
Sbjct 6677 NTSSSEAFLIGVHYLGDFASGAVIDGNTMHANYIFWRNSTIMTMSYNSVLDLSKFNCKHK 6736
Query 7054 GTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
T V++LK+ I+D++L LL G+L++R N+ + S+ LVN
Sbjct 6737 ATVVVNLKDSSISDVVLGLLKNGKLLVRNNDAICGFSNHLVN 6778
Score = 167 bits (422), Expect = 5e-39, Method: Composition-based stats.
Identities = 115/706 (16%), Positives = 224/706 (32%), Gaps = 61/706 (9%)
Query 1192 EMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTE 1251
++ + + + + VKPF + + +K + V E
Sbjct 1271 DVNWTAPLVPAVDSVVEPVVKPFYSYKNVD-FYQGDFSDLVKLPCDFVVNAANEKLSHGG 1329
Query 1252 NLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVG-DVVQEGVLTAV--VIPTKKAGG 1308
+ ID+ + ++ ++K P VG V+ E + V V+ +K
Sbjct 1330 GIAKAIDVY------TKGMLQKCSNDYIKAHGPIKVGRGVMLEALGLKVFNVVGPRKGKH 1383
Query 1309 TTEMLAKALRKVPTDNYI--TTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQE 1366
E+L KA + V ++ + T G+ +EE+ + C + ++++E
Sbjct 1384 APELLVKAYKSVFANSGVALTPLISVGIFSVPLEESLSAFLACVGDRHCKCFCYGDKERE 1443
Query 1367 ILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVD-YGARFYFY 1425
+ L + + E PV + + + K + GA ++
Sbjct 1444 AIIKYMDGLVDAI-FKEALVDTTPVQEDVQQVSQ------KPVLPNFEPFRIEGAHAFYE 1496
Query 1426 TSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPAT---VSVSSPDA 1482
+ + SL L + L+ + + + A ++V
Sbjct 1497 CNPEGLMSLGADKLVL----------FTNSNLDFCSVGKCLNDVTSGALLEAINVFKKSN 1546
Query 1483 VTAYNGYLTSSSKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPT 1542
T G + + ++ + + + LK K V + T
Sbjct 1547 KTVPAGNCVTLDCANMISITMVVLPFDGDANYDKNYARAVVKVSKLK--GKLVLAVDDAT 1604
Query 1543 TFHLDGEVITFDNLKT---LLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYL 1599
+ + + T + +++ + T D ++ V+ + TYGQQ GP +
Sbjct 1605 LYSKLSHLSVLGFVSTPDDVERFYANKSVVIKVTEDTRSVKAVKVESTATYGQQIGPCLV 1664
Query 1600 DGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTK-KWKY 1658
+ VT KP + V+PN +Y L+HT +
Sbjct 1665 NDTVVTDNKPVVAD--VVAKVVPN-----ANWDSHYGFDKAGE----FHMLDHTGFTFPS 1713
Query 1659 PQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYC 1718
VNG IK DNNC++ L LQ +F LQ + G+ A F +
Sbjct 1714 EVVNGRRVIKTTDNNCWVNVTCLQLQFARFRFKSAGLQAMWESYCTGDVAMFVHWLYWLT 1773
Query 1719 NKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQ 1778
G+ D ++ L ++ + V C + + V A + ++
Sbjct 1774 GVDKGQPSDSENALNMLSKYIVPAGSVTIERVTHDGC---CCSKRVVTAPVVNASVLKLG 1830
Query 1779 FKKGVQIPCTCGKQATKYLVQQESPFVMM-SAPPA---QYELKHGTFTCASEYTGNYQCG 1834
+ G+ C G +V + +++ P + G GN G
Sbjct 1831 VEDGL---CPHGLNYIGKVVVVKGTTIVVNVGKPVVAPSHLFLKGVSYTTFLDNGNGVVG 1887
Query 1835 HYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPV 1880
HY + DG P+T+V E + PV
Sbjct 1888 HYTVFDHGTGM-VHDGDAFVPGDLNVSPVTNVVVSEQTAVVIKDPV 1932
Score = 163 bits (413), Expect = 6e-38, Method: Composition-based stats.
Identities = 69/277 (25%), Positives = 106/277 (38%), Gaps = 19/277 (7%)
Query 993 GSEDNQTTTIQTIVEVQPQLEMELTPVVQTIE---VNSFSGYLKLTDNVYIKNADIVEEA 1049
G + T+ TI L P V ++ V F Y NV D +
Sbjct 1255 GRHQIKYDTLNTICVKDVNWTAPLVPAVDSVVEPVVKPFYSY----KNVDFYQGDFSDLV 1310
Query 1050 KKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHN 1109
K + VVNAAN L HGGG+A A++ T +Q S+DYI +GP+KVG +L
Sbjct 1311 K-LPCDFVVNAANEKLSHGGGIAKAIDVYTKGMLQKCSNDYIKAHGPIKVGRGVMLEA-- 1367
Query 1110 LAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTV 1169
L +VVGP K L+K+ F V L PL+S GIF SL + V
Sbjct 1368 LGLKVFNVVGPRKGKHAPELLVKAYKSVFANSGVALTPLISVGIFSVPLEESLSAFLACV 1427
Query 1170 -RTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPS---VEQR 1225
+ + + ++ + E + P +E +++ R
Sbjct 1428 GDRHCKCFCYGDKEREAIIKYMDGLVDAIFKEALVDTTPVQEDVQQVSQKPVLPNFEPFR 1487
Query 1226 KQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGN 1262
+ C E +L + L+L+ + N +
Sbjct 1488 IEGAHAFYECNPEGLMSLG-----ADKLVLFTNSNLD 1519
Score = 70.9 bits (172), Expect = 7e-10, Method: Composition-based stats.
Identities = 47/205 (23%), Positives = 68/205 (33%), Gaps = 29/205 (14%)
Query 172 ELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCC 231
EL GG VD CG DG P+ + + T F D++ G
Sbjct 102 ELTFGRRGGNIVP-VDQYMCGADGKPV-------LQESEWEYTDF----FADSEDGQLNI 149
Query 232 REHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKK 291
+ AW ERS+ SY Q IK T+ F + +K + KK
Sbjct 150 AGITYVKAWIVERSDVSYASQNLTSIKSITYCSTYE-----HTFLDGTAMKVARTPKIKK 204
Query 292 K------LDGFMGRIRSVYPVASPNECN----QMCLSTLMKCDHCGETSWQTGDFVKATC 341
L I S + + + + L +KC CG W GD+
Sbjct 205 NVVLSEPLATIYREIGSPFVDNGSDARSIIRRPVFLHAFVKCK-CGSYHWTVGDWTSYVS 263
Query 342 EFCGTENLTKEGATTCGYLPQNAVV 366
CG + +C +P + VV
Sbjct 264 TCCGFK-CKPVLVASCSAMPGSVVV 287
Score = 64.3 bits (155), Expect = 5e-08, Method: Composition-based stats.
Identities = 62/339 (18%), Positives = 111/339 (33%), Gaps = 37/339 (11%)
Query 1503 ETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLLSL 1562
I + G W + + IE LK + P + D E T NL ++S
Sbjct 936 NRIKVTGG---WDDVVEYINVAIEVLKD------HVEVPKYYIYDEEGGTDPNLPVMVSQ 986
Query 1563 REVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDG-ADVTKIKPHNSHEGKTFYVL 1621
+ + + D +++ + G + + + ADV +P + +G
Sbjct 987 WPLNDDTI--SQDLLDVEVVTDAPIDSEGDEVDSSAPEKVADVANSEPGD--DGLPVAPE 1042
Query 1622 PNDDTL-RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
N ++ A D + + + GL ++ + NNC++ + L
Sbjct 1043 TNVESEVEEVAATLSFIKDTPS-----TVTKDPFAFDFVSYGGLKVLRQSHNNCWVTSTL 1097
Query 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
+ LQ + + +P A AG +G LGDV + L + +
Sbjct 1098 VQLQLLGIVDDP-----AMELFSAGRVGPMVRKCYESQKAILGSLGDVSACLESLTK--D 1150
Query 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
L + K +VVC CG + +G + T + E F C +
Sbjct 1151 LHTLKITCSVVCG-CGTGERIYEG---CAFRMTPTLEPF--PYGACAQCAQVLMHTFKSI 1204
Query 1801 ESPFVMMSAPPAQYELKHGTFT--CASEYTGNYQCGHYK 1837
+ A L CA+ + G GHY
Sbjct 1205 VGTGIFCRDTTALS-LDSLVVKPLCAAAFIGK-DSGHYV 1241
>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=rep PE=1 SV=1
Length=6684
Score = 6782 bits (17597), Expect = 0.0, Method: Composition-based stats.
Identities = 2236/4994 (45%), Positives = 3069/4994 (61%), Gaps = 193/4994 (4%)
Query 2156 IVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASF 2215
+ + R+ Y L T+ ++K P K+ V
Sbjct 1830 MAGDKILRLLLEVFKYLLVL-FMCLRSTKMPKVKVK---PPLAFKDFGAKVRTL------ 1879
Query 2216 NYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTN 2275
NY++ N + LLL + + + Y ++ V+ C G + Y NS+
Sbjct 1880 NYMRQLNKPSVWRYAKLVLLL-IAIYNFFYLFVSIPVVHK-----LTCNGAVQAYKNSS- 1932
Query 2276 VTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWD----LTAFGLVAEWFLAY 2331
+ C SI C CL+ D L + L+ S W+ L+ F +A + Y
Sbjct 1933 FIKSAVCGNSILCKACLASYDELADFQHLQVTWDFKSDPLWNRLVQLSYFAFLAVFGNNY 1992
Query 2332 ILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFY 2391
+ R F + ++ + L+ SYF ++ SW + ++V ISA + +
Sbjct 1993 V---RCFLMYFVSQYLNLWLSYFG--YVEYSWFL----HVVNFESISAEFVIVVIVVKAV 2043
Query 2392 YVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWN 2451
K H+V C++ +C C + R TR+ +VNG ++ YV+ANG FCK HN+
Sbjct 2044 LALK---HIVFACSNPSCKTCSRTARQTRIPIQVVVNGSMKTVYVHANGTGKFCKKHNFY 2100
Query 2452 CVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLY------- 2504
C NCD++ +TFI DE+ RDLS K+ + TD+S V V +G Y
Sbjct 2101 CKNCDSYGFENTFICDEIVRDLSNSVKQTVYATDRSHQEVTKVECSDGFYRFYVGDEFTS 2160
Query 2505 --FDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYS 2562
+D +K + L + LD+ + GS NV ++A VY+S
Sbjct 2161 YDYDVKHKKYSSQEVLKSMLLLDDFIVYSPSGSALANV--------------RNACVYFS 2206
Query 2563 QLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAK 2622
QL+ +PI +++ L+ D+ S + +F+A N ++FNV + + K L E +
Sbjct 2207 QLIGKPIKIVNSDLLEDL--SVDFKGALFNAKKNVIKNSFNVDVSECKNL-----DECYR 2259
Query 2623 NVSLDNVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKV-- 2680
+L+ STF A +H+ I +T S NN+ + K
Sbjct 2260 ACNLNVSFSTFEMAVNN------------------AHRFGILITDRSFNNFWPSKVKPGS 2301
Query 2681 ENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPF 2740
++ D+G C+ A+ +NA+V +++W +DF +LS +K + + + F
Sbjct 2302 SGVSAMDIGKCMTSDAKIVNAKVLTQRGKSVVWLSQDFAALSSTAQKVLVKTFVEEGVNF 2361
Query 2741 KLTCATTRQVVNVV----TTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVM 2796
LT ++ T ++ K G + + QL ++ ++ I L + V
Sbjct 2362 SLTFNAVGSDDDLPYERFTESVSPKSGSGFFDVITQLKQIVILVFVFIFICGLCSVYSVA 2421
Query 2797 SKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGS-YTNDKACPLIA 2855
++ S+E Y I G+ + T +C N + F WF + G T K+CP++
Sbjct 2422 TQSYIESAEGYDYMVIKNGIVQPFDDTISCVHNTYKGFGDWFKAKYGFIPTFGKSCPIVV 2481
Query 2856 A-VITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACV 2914
V E +P +P + G L F V N+CY + D CV
Sbjct 2482 GTVFDLENMRPIPDVPAYVSIV--GRSLVFAINAAFGVTNMCYDHTGNAVSKDSYFDTCV 2539
Query 2915 LAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVR 2974
CT G V YC ++EG+ Y L PD Y G++++ P +R
Sbjct 2540 FNTACTTLTGLGGTIV-YCAKQGLVEGAKLYSDLMPDYYYEHASGNMVKLPAIIRGLGLR 2598
Query 2975 VVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPL 3034
V T + YCR G C S+AG C +V +N++ G CG + N+F
Sbjct 2599 FVKTQATTYCRVGECIDSKAGFCFGGDNWFVYDNEFGN---GYICGNSVLGFFKNVFKLF 2655
Query 3035 IQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCL 3094
+ + S +++ I+A + + Y ++F++ FG+ + ++ + +++ +
Sbjct 2656 NSNMSVVATSGAMLVNIIIACLAIAMCYGVLKFKKIFGDCTFLIVMIIVTLVVNNVSYFV 2715
Query 3095 TPVYSFLPGVYSVIYLYLTFYLTNDVSF--LAHIQWMVMFTPLVPFWITIAYIICISTKH 3152
T + +IY + +++T +++ + +++ + + P+++ AYI+
Sbjct 2716 TQ-----NTFFMIIYAIVYYFITRKLAYPGILDAGFIIAYINMAPWYVITAYILVF---- 2766
Query 3153 FYWFFSNYLKRRV---VFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYL 3208
Y + K +V +F G F FE AA+ TF+++ Y + + + + Y
Sbjct 2767 LYDSLPSLFKLKVSTNLFEGDKFVGNFESAAMGTFVIDMRSYETIVNST--SIARIKSYA 2824
Query 3209 ALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRK 3268
+NKYKY++G+M YR A HL KAL D+S + +D+LY PP S+ S LQSG RK
Sbjct 2825 NSFNKYKYYTGSMGEADYRMACYAHLGKALMDYSVNRTDMLYTPPTVSVNST-LQSGLRK 2883
Query 3269 MAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHN 3328
MA PSG VE C+V+V+ G LNGLWL D V CPRHVI S+ NYE+ + HN
Sbjct 2884 MAQPSGLVEPCIVRVSYGNNVLNGLWLGDEVICPRHVIA-SDTTRVINYENEMSSVRLHN 2942
Query 3329 FLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGV 3388
F V NV L V+ + L LKV+ NP TP++KF I+ G++F++LACY G P V
Sbjct 2943 FSVSKNNVFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIKAGESFNILACYEGCPGSV 3002
Query 3389 YQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPF 3448
Y MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++ EG YG +
Sbjct 3003 YGVNMRSQGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLELGNGSHVGSNFEGEMYGGY 3062
Query 3449 VDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQD 3508
D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + +L +N A ++ L+
Sbjct 3063 EDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSLESYNTWAKTNSFTELSS- 3121
Query 3509 HVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTF 3568
D L+A+TG +V + S+ L G GRTIL L DEFTP +V+RQ GV
Sbjct 3122 -TDAFSMLAAKTGQSVEKLLDSIVRL-NKGFGGRTILSYGSLCDEFTPTEVIRQMYGVNL 3179
Query 3569 QSAVKRTIKGTHHWLLLTILTSLLVLVQS----TQWSLFFFLYENAFLPFAMGIIAMSAF 3624
Q+ ++ I+T++ +L ++ F ++ +S
Sbjct 3180 QAGKVKS-------FFYPIMTAMTILFAFWLEFFMYTPFTWINPTFVSIVLAVTTLISTV 3232
Query 3625 AMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
+ +KHK F F+LPS+ V N+ + S+ + + ++ +T ++ ++
Sbjct 3233 FVSGIKHKMLFFMSFVLPSVILVTAHNL-FWDFSYYESLQSIVENTNTMFLPVDMQGVML 3291
Query 3685 YASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQA----------ISMW 3734
++ + + R + + +L + V D+ ++M
Sbjct 3292 TVFCFIVFVTYSVRFFTCKQSWFSLAVTTILVIFNMVKIFGTSDEPWTENQIAFCFVNML 3351
Query 3735 ALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYF 3794
+I+S+T+ VV +A IV + F ++CI +VY GY CY+
Sbjct 3352 TMIVSLTTKDWMVVIASYRIAYYIVVCVM--PSAFVSDFGFMKCISIVYMACGYLFCCYY 3409
Query 3795 GLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIK 3854
G+ +NR+ +T GVY + VS E +YM + L PKN+ DA L+ KL+GVGGK IK
Sbjct 3410 GILYWVNRFTCMTCGVYQFTVSAAELKYMTANNLSAPKNAYDAMILSAKLIGVGGKRNIK 3469
Query 3855 VATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSL 3914
++TVQSK++++KCT+VVLL +L ++ VES+SK W CV LHN+I L D EK+++L
Sbjct 3470 ISTVQSKLTEMKCTNVVLLGLLSKMHVESNSKEWNYCVGLHNEINLCDDPEIVLEKLLAL 3529
Query 3915 LSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSE 3974
++ LS D+++L E +N LQ++AS +++LPS+ A A+ E+A N S
Sbjct 3530 IAFFLSKHNTCDLSELIESYFENTTILQSVASAYAALPSWIALEKARADLEEAKKNDVSP 3589
Query 3975 VVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLF 4034
+LK+L K+ N+AKS+F+R+A++Q+KL+KMA+QA MYK+AR+ D+++K+ SAM ++LF
Sbjct 3590 QILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLF 3649
Query 4035 TMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASA 4094
ML+KLD ++N II+ AR+G +PL+IIP +A +L+V+ P + YA A
Sbjct 3650 GMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATRLVVITPSLEVFSKIRQENNVHYAGA 3709
Query 4095 LWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSC 4154
+W I +V DA+ V L E++ N NL WPL +T R KLQNNE+ P L++ +
Sbjct 3710 IWTIVEVKDANGSHVHLKEVTAANELNLTWPLSITCERTT---KLQNNEIMPGKLKERAV 3766
Query 4155 AAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCR 4214
A T + A + G F+ A ++ +LK+ ++ + I ELE P R
Sbjct 3767 RASATLDGEAFGSGKALMASESGKSFMYAFIASDNNLKYVKWESN--NDIIPIELEAPLR 3824
Query 4215 FVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAV 4274
F D GP+VKYLYF+K LN L RG VLG + ATVRLQAG TE P+NS++L+ CAF+
Sbjct 3825 FYVDGANGPEVKYLYFVKNLNTLRRGAVLGYIGATVRLQAGKPTEHPSNSSLLTLCAFSP 3884
Query 4275 DAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHI 4334
D AKAY D + G QP+ NCVKML G G A+T EAN Q+S+GGAS C+YCRCH+
Sbjct 3885 DPAKAYVDAVKRGMQPVNNCVKMLSNGAGNGMAVTNGVEANTQQDSYGGASVCIYCRCHV 3944
Query 4335 DHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA 4394
+HP G C KGK+VQIPT DP+ F ++N VC VCG W GC CD R M
Sbjct 3945 EHPAIDGLCRYKGKFVQIPTG-TQDPIRFCIENEVCVVCGCWLNNGCMCD--RTSMQSFT 4001
Query 4395 DAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDED 4454
QS+LNRV G SAARL PC GT D V RAFDIYN VA KFLKTNC RF+ D+
Sbjct 4002 VDQSYLNRVRGSSAARLEPC-NGTDPDHVSRAFDIYNKDVACIGKFLKTNCSRFRNLDKH 4060
Query 4455 DNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKY 4514
D+Y++VKR T + HE+ YN LKD AVA+HDFF ++ +++R+ LTKY
Sbjct 4061 ----DAYYIVKRCTKTVMDHEQVCYNDLKDSGAVAEHDFFTYKEGRCEFGNVARRNLTKY 4116
Query 4515 TMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERV 4574
TM DL YA+R+FDE NC+ LKEILVT C +++F KDW+D VEN I VYA LG V
Sbjct 4117 TMMDLCYAIRNFDEKNCEVLKEILVTVGACTEEFFENKDWFDPVENEAIHEVYAKLGPIV 4176
Query 4575 RQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLM 4634
A+LK V FCDA+ G +GV+TLDNQDLNGN+YDFGDF++T PG G V SYYS +M
Sbjct 4177 ANAMLKCVAFCDAIVEKGYIGVITLDNQDLNGNFYDFGDFVKTAPGFGCACVTSYYSYMM 4236
Query 4635 PILTLTRALTAESHVDTDL-TKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNC 4693
P++ +T L +E+ V +D+ Y ++DLL YDFTE + LF +YFKYWD+TYHPNC +C
Sbjct 4237 PLMGMTSCLESENFVKSDIYGSDYKQYDLLAYDFTEHKEYLFQKYFKYWDRTYHPNCSDC 4296
Query 4694 LDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNL 4753
D CI+HCANFN LFS P T+FGPLVRK+ +DGVP VV+ GYHF++LG+V N DV L
Sbjct 4297 TSDECIIHCANFNTLFSMTIPMTAFGPLVRKVHIDGVPVVVTAGYHFKQLGIVWNLDVKL 4356
Query 4754 HSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYD 4813
+ +LS +LL + DP + AS LLD+RT CFS+AAL+ + +QTVKPG+FNKDFYD
Sbjct 4357 DTMKLSMTDLLRFVTDPTLLVASSPALLDQRTVCFSIAALSTGITYQTVKPGHFNKDFYD 4416
Query 4814 FAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFD 4873
F +GFF+EGS + LKHFFFAQ G AA++D++YYRYN T+ DI Q FV ++V KYF+
Sbjct 4417 FITERGFFEEGSELTLKHFFFAQGGEAAMTDFNYYRYNRVTVLDICQAQFVYKIVGKYFE 4476
Query 4874 CYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQ 4933
CYDGGCINA +V+V N DKSAG+P NK+GKARLYY+++SYE+QDALFA TKRNV+PT+TQ
Sbjct 4477 CYDGGCINAREVVVTNYDKSAGYPLNKFGKARLYYETLSYEEQDALFALTKRNVLPTMTQ 4536
Query 4934 MNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNM 4993
MNLKYAIS K RARTV GVS+ STMT RQ+HQK LKSIAATR ATVVIG++KFYGGW NM
Sbjct 4537 MNLKYAISGKARARTVGGVSLLSTMTTRQYHQKHLKSIAATRNATVVIGSTKFYGGWDNM 4596
Query 4994 LKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQ 5053
LK + DV+N LMGWDYPKCDRA+PNM+R+ ++++L KH CC+ + RFYRL+NE AQ
Sbjct 4597 LKNLMRDVDNGCLMGWDYPKCDRALPNMIRMASAMILGSKHVGCCTHNDRFYRLSNELAQ 4656
Query 5054 VLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVR 5113
VL+E+V C G Y KPGGT+SGD TTAYANS FNI QAV+ANVN LL D N + V+
Sbjct 4657 VLTEVVHCTGGFYFKPGGTTSGDGTTAYANSAFNIFQAVSANVNKLLGVDSNACNNVTVK 4716
Query 5114 NLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKN 5173
++Q ++Y+ YR+ +D +FV E+++YLRKHFSMMILSDD VVC+N YA G VA I
Sbjct 4717 SIQRKIYDNCYRSSSIDEEFVVEYFSYLRKHFSMMILSDDGVVCYNKDYADLGYVADINA 4776
Query 5174 FKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAG 5233
FK+ LYYQNNVFMS +KCW E DL+ GPHEFCSQHT+ + D YLPYPDPSRIL AG
Sbjct 4777 FKATLYYQNNVFMSTSKCWVEPDLSVGPHEFCSQHTLQIVGPDGDYYLPYPDPSRILSAG 4836
Query 5234 CFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLD 5293
FVDDIVKTD +M+ER+VSLAIDAYPLTKHP Y VF+ L +++ L L +LD
Sbjct 4837 VFVDDIVKTDNVIMLERYVSLAIDAYPLTKHPKPAYQKVFYTLLDWVKHLQKNLNAGVLD 4896
Query 5294 MYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKC 5353
+SV + + ++W EFY ++Y TVLQA G CV+C SQT LRCG C+RRP LC KC
Sbjct 4897 SFSVTMLEEGQDKFWSEEFYASLYEKSTVLQAAGMCVVCGSQTVLRCGDCLRRPLLCTKC 4956
Query 5354 CYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQV 5413
YDHV+ T HK ++S+ PYVC+ GC+V DVT+L+LGG+SYYC +HKP +SFPLCANG V
Sbjct 4957 AYDHVMGTKHKFIMSITPYVCSFNGCNVNDVTKLFLGGLSYYCMNHKPQLSFPLCANGNV 5016
Query 5414 FGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSY 5473
FGLYK++ VGS+ V DFN +A DWTN DY LAN E LK+FAAET+KA EE+ K Y
Sbjct 5017 FGLYKSSAVGSEAVEDFNKLAVSDWTNVEDYKLANNVKESLKIFAAETVKAKEESVKSEY 5076
Query 5474 GIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYG-DA 5532
A ++EV+ +E+ L WE K +PPLNRN VFT ++++K++K+Q+GE+ FE+ +YG D+
Sbjct 5077 AYAVLKEVIGPKEIVLQWEASKTKPPLNRNSVFTCFQISKDTKIQLGEFVFEQSEYGSDS 5136
Query 5533 VVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVAN 5592
V Y+ T+TYKL G FVLTSH V PL AP LV QE Y I+ LYP NI++ +++ V
Sbjct 5137 VYYKSTSTYKLTPGMIFVLTSHNVSPLKAPILVNQEKYNTISKLYPVFNIAEAYNTLVPY 5196
Query 5593 YQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID 5652
YQ +G QK++T+QGPPG+GKSH IGL LYYP ARIVYTACSHAAVDALCEKA K +D
Sbjct 5197 YQMIGKQKFTTIQGPPGSGKSHCVIGLGLYYPQARIVYTACSHAAVDALCEKAAKNFNVD 5256
Query 5653 KCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVN 5712
+CSRIIP R RV+C+ FK N+T QY+FCTVNALPE + DIVV DE+SM TNYDLSV+N
Sbjct 5257 RCSRIIPQRIRVDCYTGFKPNNTNAQYLFCTVNALPEASCDIVVVDEVSMCTNYDLSVIN 5316
Query 5713 ARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEI 5772
+RL KH VY+GDP QLPAPRTL+ KG L+P+ +N V + M T+GPD+FL C RCPAEI
Sbjct 5317 SRLSYKHIVYVGDPQQLPAPRTLINKGVLQPQDYNVVTKRMCTLGPDVFLHKCYRCPAEI 5376
Query 5773 VDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRK 5832
V TVSALVY+NK +S QCFKMF KG + + +S+IN Q+ VV+ FL NP WRK
Sbjct 5377 VKTVSALVYENKFVPVNPESKQCFKMFVKGQVQIESNSSINNKQLEVVKAFLAHNPKWRK 5436
Query 5833 AVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRA 5892
AVFISPYNSQN VA ++LGL TQTVDS+QGSEYDYVI+TQT++T H+ NVNRFNVAITRA
Sbjct 5437 AVFISPYNSQNYVARRLLGLQTQTVDSAQGSEYDYVIYTQTSDTQHATNVNRFNVAITRA 5496
Query 5893 KVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAEN-VTGLFKDCSKVITGLHPTQAPTH 5951
KVGILCIM DR +Y+ L F L+ + LQA+ GLFKDCSK + P A T+
Sbjct 5497 KVGILCIMCDRTMYENLDFYELKDSKI---GLQAKPETCGLFKDCSKSEQYIPPAYATTY 5553
Query 5952 LSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRA 6010
+S+ FKT +GL V+I KD+ Y +IS MGF+ + GY +F TR+ A+R+VRA
Sbjct 5554 MSLSDNFKTSDGLAVNIG--TKDVKYANVISYMGFRFEANIPGYHTLFCTRDFAMRNVRA 5611
Query 6011 WIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQ 6070
W+GFDVEG H + VGTN+PLQLGFS GV+ V G V T V A+ PPG+Q
Sbjct 5612 WLGFDVEGAHVCGDNVGTNVPLQLGFSNGVDFVVQTEGCVITEKGNSIEVVKARAPPGEQ 5671
Query 6071 FKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPER 6130
F HLIPLM KG PW++VR +IVQM+ D LSD ++FVLWA G ELT+M+YFVKIG +
Sbjct 5672 FAHLIPLMRKGQPWHIVRRRIVQMVCDYFDGLSDILIFVLWAGGLELTTMRYFVKIGRPQ 5731
Query 6131 TCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHG 6190
C C + ATC+S++ YAC+ H++G DY+YNP+ ID+QQWG+TG+L NH C +H
Sbjct 5732 KCE-CGKSATCYSSSQSVYACFKHALGCDYLYNPYCIDIQQWGYTGSLSMNHHEVCNIHR 5790
Query 6191 NAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADK 6250
N HVAS DAIMTRCLA+H+CFVKRVDW+I YP I +E KIN A R VQ V+KAAL
Sbjct 5791 NEHVASGDAIMTRCLAIHDCFVKRVDWSIVYPFIDNEEKINKAGRIVQSHVMKAALKIFN 5850
Query 6251 FPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFW 6310
+HD+GNPK I+C + W YD P ++ L Y Y H +G+ LFW
Sbjct 5851 PAAIHDVGNPKGIRCA-TTPIPWFCYDRDPINNNVR---CLDYDYMVHGQ--MNGLMLFW 5904
Query 6311 NCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFF 6370
NCNVD YP SIVCRFDTR S L+L GC+GG+LYVN HAFHTPA+D+ AF LK +PFF
Sbjct 5905 NCNVDMYPEFSIVCRFDTRTRSKLSLEGCNGGALYVNNHAFHTPAYDRRAFAKLKPMPFF 5964
Query 6371 YYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAG 6430
YY DS CE V +YVPLKS CIT+CN+GGAVC+ HA YR Y++ YN+ + AG
Sbjct 5965 YYDDSNCE----LVDGQPNYVPLKSNVCITKCNIGGAVCKKHAALYRAYVEDYNIFMQAG 6020
Query 6431 FSLWVYKQFDTYNLWNTFTR---LQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKV 6487
F++W + FDTY LW+ F LQSLENVAFNVV KG F G +G++P ++I + + +
Sbjct 6021 FTIWCPQNFDTYMLWHGFVNSKALQSLENVAFNVVKKGAFTGLKGDLPTAVIADKIMVRD 6080
Query 6488 DGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAH 6547
D +F NKT+LP NVAFEL+AKR + P + IL NLGV V+WDY+ + P
Sbjct 6081 GPTDKCIFTNKTSLPTNVAFELYAKRKLGLTPPLTILRNLGVVATYKFVLWDYEAERPFS 6140
Query 6548 ISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSV 6607
T VCS TD+ + + FD + G + F R+ VLI+ +VKGL ++
Sbjct 6141 NFTKQVCSYTDLDSE--------VVTCFDNSIAGSFERFTTTRDAVLISNNAVKGLS-AI 6191
Query 6608 GPKQASLNGVTL--IGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDF 6665
+ LN + + +G T + Y +K V+Q+ ++Y+TQ R + FKPRS ME DF
Sbjct 6192 KLQYGLLNDLPVSTVGNKPVTWYIYVRKNGEYVEQI-DSYYTQGRTFETFKPRSTMEEDF 6250
Query 6666 LELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFI-PMD 6724
L + FI++Y LE Y FEH+V+GD S + +GG+HLLI + K F +++F+ D
Sbjct 6251 LSMDTTLFIQKYGLEDYGFEHVVFGDVSKTTIGGMHLLISQVRLAKMGLFSVQEFMNNSD 6310
Query 6725 STVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLW 6784
ST+K+ IT A SSK VC+ +D+LLDDFV IIKS DL+VVSKVV V +D +MLW
Sbjct 6311 STLKSCCITYADDPSSKNVCTYMDILLDDFVTIIKSLDLNVVSKVVDVIVDCKAWRWMLW 6370
Query 6785 CKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAK 6844
C++ H++TFYP+LQS++ W PG +MP LYK+QRM LE+C+L NYG LP GI NV K
Sbjct 6371 CENSHIKTFYPQLQSAE-WNPGYSMPTLYKIQRMCLERCNLYNYGAQVKLPDGITTNVVK 6429
Query 6845 YTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSD 6904
YTQLCQYLNT TL VP+ MRV+H GA GVAPG+ VLR+WLP +LVD+DL D+VSD
Sbjct 6430 YTQLCQYLNTTTLCVPHKMRVLHLGAAGASGVAPGSTVLRRWLPDDAILVDNDLRDYVSD 6489
Query 6905 ADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGS 6964
AD ++ GDC +++ +K+DL++SD+YD TK++ EN SK+GFFTYI GFI++KL+LGGS
Sbjct 6490 ADFSVTGDCTSLYIEDKFDLLVSDLYDGSTKSIDGENTSKDGFFTYINGFIKEKLSLGGS 6549
Query 6965 VAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGK--PREQIDGYVM 7022
VAIKITE SWN DLY+L+ F +WT F T+VN SSSE FLIG NYLG + +DG +M
Sbjct 6550 VAIKITEFSWNKDLYELIQRFEYWTVFCTSVNTSSSEGFLIGINYLGPYCDKAIVDGNIM 6609
Query 7023 HANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRE 7082
HANYIFWRN+ + LS S+ D KF + +++LKE ++N+M++ LL KG+L+IR
Sbjct 6610 HANYIFWRNSTIMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVIGLLRKGKLLIRN 6669
Query 7083 NNRVVISSDVLVNN 7096
N +++ + VN
Sbjct 6670 NGKLLNFGNHFVNT 6683
Score = 204 bits (520), Expect = 2e-50, Method: Composition-based stats.
Identities = 82/409 (20%), Positives = 147/409 (36%), Gaps = 46/409 (11%)
Query 874 VVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKL--------ASHMYCSFY 925
+V + + L P+ E G+ D + T G
Sbjct 1171 IVLERAVFKLTPLKESF-NYGVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVK 1229
Query 926 PPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEE---EQEEDWLDD 982
P G + + D KPL+ ++ L + E +
Sbjct 1230 PVMHAVYTGTTQNGHYMVDDIEHGYCVDGMGIKPLKKRCYTSTLFINANVMTRAEKPKQE 1289
Query 983 DSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKN 1042
+ V QQ E+N+++ + ++ P+ + + P + +++ + G L + N
Sbjct 1290 FKVEKVEQQPIVEENKSSIEKEEIQ-SPKNDDLILPFYKAGKLSFYQGALDVLINF---- 1344
Query 1043 ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGS 1102
++P V+VNAAN LKH GGVA A++ T + S DY+ N + G +
Sbjct 1345 ---------LEPDVIVNAANGDLKHMGGVARAIDVFTGGKLTERSKDYLKKNKSIAPGNA 1395
Query 1103 CVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQH-EVLLAPLLSAGIFGADPIHS 1161
L+ VGP L + Y+ + +L PL+S GIF
Sbjct 1396 VFFENVIEHLSVLNAVGPRNGDSRVEAKLCNVYKAIAKCEGKILTPLISVGIF------- 1448
Query 1162 LRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKI--AEIPKEEVKPFITESK 1219
VR L K + D+ ++ F+ E+Q + IP + + +
Sbjct 1449 ------NVRLETSLQCLLKTVNDRGLNVFVYTDQERQTIENFFSCSIPVNVTEDNVNHER 1502
Query 1220 PSVEQRKQDDKKIKACV----EEVTTTLEETKFLTENLLLYIDINGNLH 1264
SV K +++K V ++VT L + + ++ IDI+ H
Sbjct 1503 VSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAFDVGQKVIKAIDIDWQAH 1551
Score = 172 bits (437), Expect = 1e-40, Method: Composition-based stats.
Identities = 68/301 (23%), Positives = 109/301 (36%), Gaps = 41/301 (14%)
Query 1610 HNSHEGKTFYVLPNDDTL-RVEAFEYYHTTDP----SFLGRYMSALNHTKKWKYPQVNGL 1664
+ E +T V T V+ E DP + +K +NG
Sbjct 1024 SSQEEVETVEVADITSTEEDVDIVEVSAKDDPWAAAVDVQEAEQFNPSLPPFKTTNLNGK 1083
Query 1665 TSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGE 1724
+K DNNC++ LQ + FN +A+ + + G+ +F L A G
Sbjct 1084 IILKQGDNNCWINACCYQLQAFDF-FN----NEAWEKFKKGDVMDFVNLCYAATTLARGH 1138
Query 1725 LGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQ 1784
GD + + + + K VL C CG+++ L E ++ T E F GV
Sbjct 1139 SGDAEYLLELMLN--DYSTAKIVLAAKCG-CGEKEIVL---ERAVFKLTPLKESFNYGVC 1192
Query 1785 IPC----TCGKQATKY-------LVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQC 1833
C TC + + ++ +++P M P + + YTG Q
Sbjct 1193 GDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHAV----------YTGTTQN 1242
Query 1834 GHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEID 1893
GHY + E YC+DG + K + + + +F N T KP V E
Sbjct 1243 GHY-MVDDIEHGYCVDG-MGIKPLKKRCYTSTLFINANVMTRAEKPKQEF--KVEKVEQQ 1298
Query 1894 P 1894
P
Sbjct 1299 P 1299
Score = 140 bits (354), Expect = 4e-31, Method: Composition-based stats.
Identities = 55/296 (19%), Positives = 101/296 (34%), Gaps = 23/296 (8%)
Query 1554 DNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQF-GPTYLDGADVTKIKPHNS 1612
D + + +I V T DN+N V TYG+Q G + DVT P
Sbjct 1475 DQERQTIENFFSCSIPVNVTEDNVNHERVSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAF 1534
Query 1613 HEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADN 1672
G+ + ++ +Y D + ++ + K++ + K DN
Sbjct 1535 DVGQKV-----IKAIDIDWQAHYGFRDA---AAFSASSHDAYKFEVVTHSNFIVHKQTDN 1586
Query 1673 NCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETM 1732
NC++ L LQ+++ ++ P ++ + + F ++ GE GD +
Sbjct 1587 NCWINAICLALQRLKPQWKFPGVRGLWNEFLERKTQGFVHMLYHISGVKKGEPGDAELML 1646
Query 1733 SYLFQHANLDSCKRV-LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGK 1791
L + D V C C + G + G C G
Sbjct 1647 HKLGDLMDNDCEIIVTHTTACDKC-AKVEKFVGPVVAAPLAI-------HGTDETCVHGV 1698
Query 1792 QATKYLVQQESPFVMMS--APPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETL 1845
+ Q + + S P L+ + C Y+G+ + GHY + ++ L
Sbjct 1699 SVNVKVTQIKGTVAITSLIGPIIGEVLEATGYIC---YSGSNRNGHYTYYDNRNGL 1751
Score = 67.8 bits (164), Expect = 5e-09, Method: Composition-based stats.
Identities = 49/251 (20%), Positives = 75/251 (30%), Gaps = 43/251 (17%)
Query 174 MRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCRE 233
++ G YVD CG DG P+ + +
Sbjct 102 LKIARTGRGAIYVDQYMCGADGKPV----------------IEGDFKDYFGDEDIIEFEG 145
Query 234 HEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKL 293
E+ AW T R EK QT F I+ + N + P+ + N + + P V+K
Sbjct 146 EEYHCAWTTVRDEKPLNQQTLFTIQEIQY----NLDIPHKL--PNCATRHVAPPVKKNSK 199
Query 294 DGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATC-EFCGTENLTKE 352
+ +Y + S M C + T F+ AT CG+E+
Sbjct 200 IVLSEDYKKLYDIFG---------SPFMGNGDCLSKCFDTLHFIAATLRCPCGSESSGVG 250
Query 353 GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFS 412
T C S +L + + T + G F CV
Sbjct 251 DWT-----------GFKTACCGLSGKVKGVTLGDIKPGDAVVTSMSAGKGVKFFANCVLQ 299
Query 413 YVGCHNKCAYW 423
Y G + W
Sbjct 300 YAGDVEGVSIW 310
Score = 48.9 bits (115), Expect = 0.003, Method: Composition-based stats.
Identities = 50/302 (17%), Positives = 96/302 (32%), Gaps = 27/302 (9%)
Query 748 PTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMM 807
V+ + +P+ +E V+ G + I G + +D Y
Sbjct 811 DVPVVDNGTISTADWSEPILLEPAEYVKPKNNGNVIVIAGYTFYKDEDEHFYP--YGFGK 868
Query 808 VTNNTFTLKGGAPTKVTFGDD-TVIEVQGYKSVNITFELD-ERIDKVLNEKCSA---YTV 862
+ + GG V+F ++ V E+ V + FE D E + VL +T
Sbjct 869 IVQRMYNKMGGGDKTVSFSEEVDVQEIAPVTRVKLEFEFDNEIVTGVLERAIGTRYKFTG 928
Query 863 ELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
E E DA+ TL G++L+ + +++D G F + +
Sbjct 929 TTWEEFEESISEELDAIFDTL-------ANQGVELEGY-----FIYDTCGGFDIKNPDGI 976
Query 923 SFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDD 982
D + + E + E+D + + +E + +EE E + D
Sbjct 977 MISQYDINITADEKSEVSASSEEEEVESVEEDPENEIVEASEGAEGTSSQEEVETVEVAD 1036
Query 983 DSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKN 1042
+ + V+VQ + + + F L + +K
Sbjct 1037 ITSTEEDVDIVEVSAKDDPWAAAVDVQEAEQFNPS-------LPPFKT-TNLNGKIILKQ 1088
Query 1043 AD 1044
D
Sbjct 1089 GD 1090
>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus
229E OX=11137 GN=rep PE=1 SV=1
Length=6758
Score = 6772 bits (17569), Expect = 0.0, Method: Composition-based stats.
Identities = 2249/5016 (45%), Positives = 3109/5016 (62%), Gaps = 183/5016 (4%)
Query 2124 THGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVC-------TNYMPYFFTLL 2176
H L+ ++ + Y P N + + N++ FFT L
Sbjct 1882 KHDLSLLSVTSVVMVGGYVAPVNTVKPKPVINQLDEKAQKFFDFGDFLIHNFV-IFFTWL 1940
Query 2177 LQLCTFTRST----NSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIW 2232
L + T ++ + +I A P +S+ K+ L+AS LKS W
Sbjct 1941 LSMFTLCKTAVTTGDVKIMAKAPQRTGVVLKRSL-KYNLKASAAVLKSK----------W 1989
Query 2233 FLLLSVC-LGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVC 2291
+LL L LIY+ ++ +L G ++C+ GY S N YC GS+ C +C
Sbjct 1990 WLLAKFTKLLLLIYTLYSVVLLCVRFGPFNFCSETVNGYAKS-NFVKDDYCDGSLGCKMC 2048
Query 2292 LSGLDSLDTYPSLETIQITISSFKW-DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLF 2350
L G L + L+ + I+ + ++ F ++ + + R F + +A ++
Sbjct 2049 LFGYQELSQFSHLDVVWKHITDPLFSNMQPFIVMVLLLIFGDNYLRCFLLYFVAQMISTV 2108
Query 2351 FSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCM 2410
+ + +W + P + + V HV+ GC + C+
Sbjct 2109 GVFLG--YKETNWFLHF-------IPFDVICDELLVTVIVIKVISFVRHVLFGCENPDCI 2159
Query 2411 MCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVA 2470
C K R R TIVNGV+RSFYV ANGG FCK H + CV+CD++ GSTFI+ EV+
Sbjct 2160 ACSKSARLKRFPVNTIVNGVQRSFYVNANGGSKFCKKHRFFCVDCDSYGYGSTFITPEVS 2219
Query 2471 RDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRAN 2530
R+L K + PT + ++D V +NG LY + + + S + + +
Sbjct 2220 RELGNITKTNVQPTGPAYVMIDKVEFENGFYRLYSCETFWRYNFDITESKYSCKEVFKNC 2279
Query 2531 NTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKM 2590
N + IVF+ + K+ASVY+SQL+C+PI L+D L+S + S + +
Sbjct 2280 NV----LDDFIVFNNNGT-NVTQVKNASVYFSQLLCRPIKLVDSELLSTL--SVDFNGVL 2332
Query 2591 FDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKD 2650
AY++ ++F L ++ AE + A +S+ +
Sbjct 2333 HKAYIDVLRNSFGKD---LNANMSLAECKRALGLSI--------------------SDHE 2369
Query 2651 VVECLKLSHQSDIEVTGDSCNNYMLTYNKVE-NMTPRDLGACIDCSARHINAQVAKSHNI 2709
+ +H+ D+ ++ S NN++ +Y K E ++ DL C+ A+ +NA V
Sbjct 2370 FTSAISNAHRCDVLLSDLSFNNFVSSYAKPEEKLSAYDLACCMRAGAKVVNANVLTKDQT 2429
Query 2710 ALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNN- 2768
++W+ KDF SLS + RK I +K L F LT + V + T I K G
Sbjct 2430 PIVWHAKDFNSLSAEGRKYIVKTSKAKGLTFLLTINENQAVTQIPATSIVAKQGAGDAGH 2489
Query 2769 ---WLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDT 2825
WL L + + F F ++S S E +K I+ G ++ +
Sbjct 2490 SLTWLWLLCGLVCLIQFYLCFFMPYFMYDIVS-----SFEGYDFKYIENGQLKNFEAPLK 2544
Query 2826 CFANKHADFDTWFSQRGGS-YTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHF 2884
C N +F+ W + G N ++CP++ V E+ V G+P + G L F
Sbjct 2545 CVRNVFENFEDWHYAKFGFTPLNKQSCPIVVGV--SEIVNTVAGIPSNVYLV--GKTLIF 2600
Query 2885 LPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVA 2944
+ +CY + C+ + CT + G V YCY+T ++EGS+
Sbjct 2601 TLQAAFGNAGVCYD-----IFGVTTPEKCIFTSACTRLEGLGGNNV-YCYNTALMEGSLP 2654
Query 2945 YESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCERSEAGVCVSTSGR 3003
Y S++ + Y +G+ I+ P +G R V T ++YCR G C S AGVC +
Sbjct 2655 YSSIQANAYYKYDNGNFIKLPEVIAQGFGFRTVRTIATKYCRVGECVESNAGVCFGFD-K 2713
Query 3004 WVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYY 3063
W +N+ R G CG NL+ N+ + +S I+ + +
Sbjct 2714 WFVNDG--RVANGYVCGTGLWNLVFNILSMFSSSFSVAAMSGQILLNCALGAFAIFCCFL 2771
Query 3064 FMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFL 3123
+FRR FG+ S V + L++ +T + Y+++Y + T L +++
Sbjct 2772 VTKFRRMFGDLSVGVCTVVVAVLLNNVSYIVTQNLVTMIA-YAILYFFATRSL--RYAWI 2828
Query 3124 AHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFNGVSF-STFEEAA 3179
+++ + P+W+ Y + + T + LK +V +F G F TFE AA
Sbjct 2829 WCAAYLIAYISFAPWWLCAWYFLAMLTG----LLPSLLKLKVSTNLFEGDKFVGTFESAA 2884
Query 3180 LCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALN 3239
TF+++ Y KL + + + Y A YN+YKY+SG + YR A +LAKA+
Sbjct 2885 AGTFVIDMRSYEKLANSI--SPEKLKSYAASYNRYKYYSGNANEADYRCACYAYLAKAML 2942
Query 3240 DFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVV 3299
DFS +D+LY PP S S LQ+G RKMA PSG VE C+V+V G T LNGLWL D+V
Sbjct 2943 DFSRDHNDILYTPPTVSYGST-LQAGLRKMAQPSGFVEKCVVRVCYGNTVLNGLWLGDIV 3001
Query 3300 YCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANP 3359
YCPRHVI ++ +Y+ HNF + +G L V+G +M LK+KV N
Sbjct 3002 YCPRHVIASNTT-SAIDYDHEYSIMRLHNFSIISGTAFLGVVGATMHGVTLKIKVSQTNM 3060
Query 3360 KTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDC 3419
TP++ F ++ G+ F++LACY+G GV+ MR N+TI+GSF+NG+CGS G+N+
Sbjct 3061 HTPRHSFRTLKSGEGFNILACYDGCAQGVFGVNMRTNWTIRGSFINGACGSPGYNLKNGE 3120
Query 3420 VSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGD 3479
V F YMH +EL +G H G+ +G YG F D+ Q + +TVNV+A+LYAA++NG
Sbjct 3121 VEFVYMHQIELGSGSHVGSSFDGVMYGGFEDQPNLQVESANQMLTVNVVAFLYAAILNGC 3180
Query 3480 RWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGM 3539
W+L + +N A + + + D L+A+TG+ V + +++ +L NG
Sbjct 3181 TWWLKGEKLFVEHYNEWAQANGFTAMNGE--DAFSILAAKTGVCVERLLHAIQ-VLNNGF 3237
Query 3540 NGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQ 3599
G+ ILG + L DEF+ +VV+Q GV QS K T + +++ V+ +
Sbjct 3238 GGKQILGYSSLNDEFSINEVVKQMFGVNLQSG-----KTTSMFKSISLFAGFFVMFWAEL 3292
Query 3600 W--SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPA 3657
+ + ++ PF + ++A+S VKHK FL +FLLPS+ A N +
Sbjct 3293 FVYTTTIWVNPGFLTPFMILLVALSLCLTFVVKHKVLFLQVFLLPSIIVAAIQNCAW--D 3350
Query 3658 SWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTL 3717
V +++ + S+ ++ V + + +L T R + L +++ +
Sbjct 3351 YHVTKVLAEKFDYNVSVMQMDIQGFVNIFICLFVALLHTWRFAKERCTHWCTYLFSLIAV 3410
Query 3718 VYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARG-IVFMCVEYCPIFFITGNTL 3776
+Y Y +S+ +++ SN + + + R + F+ VEY F + +
Sbjct 3411 LYTALYSY---DYVSLLVMLLCAISNEWYIGAIIFRICRFGVAFLPVEYVSYF----DGV 3463
Query 3777 QCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSID 3836
+ ++L Y LG+ Y+GL +NR+ + TLGVYD+ VS EF+YM + GL P D
Sbjct 3464 KTVLLFYMLLGFVSCMYYGLLYWINRFCKCTLGVYDFCVSPAEFKYMVANGLNAPNGPFD 3523
Query 3837 AFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHN 3896
A L+ KL+G+GG IKV+TVQSK++D+KCT+VVL+ +L + + S+SK WA CV++HN
Sbjct 3524 ALFLSFKLMGIGGPRTIKVSTVQSKLTDLKCTNVVLMGILSNMNIASNSKEWAYCVEMHN 3583
Query 3897 DILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA 3956
I L D A E +++LL+ LS + L + +N + LQ++AS F +PS+ A
Sbjct 3584 KINLCDDPETAQELLLALLAFFLSKHSDFGLGDLVDSYFENDSILQSVASSFVGMPSFVA 3643
Query 3957 FATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQA 4016
+ TA++ YE AVANG S ++K+LKK++NVAK+EFDR++++Q+K+ +MA+QA MYK+A
Sbjct 3644 YETARQEYENAVANGSSPQIIKQLKKAMNVAKAEFDRESSVQKKINRMAEQAAAAMYKEA 3703
Query 4017 RSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPD 4076
R+ ++++KV SAM ++LF MLR+LD +++ I+N AR+G VPL++IP T+AA+L+VV+PD
Sbjct 3704 RAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNMARNGVVPLSVIPATSAARLVVVVPD 3763
Query 4077 YNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSA 4136
++++ YA +W +Q+V D D K V L +++ +N L WPLI+T R
Sbjct 3764 HDSFVKMMVDGFVHYAGVVWTLQEVKDNDGKNVHLKDVTKENQEILVWPLILTCER---V 3820
Query 4137 VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARF 4196
VKLQNNE+ P ++ + ++ NAL YN G F+ A ++ +K+ ++
Sbjct 3821 VKLQNNEIMPGKMKVKATKGEGDGGITSEGNAL--YNNEGGRAFMYAYVTTKPGMKYVKW 3878
Query 4197 PKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGN 4256
G T+ ELEPPCRFV DTP GP++KYLYF+K LNNL RG VLG + ATVRLQAG
Sbjct 3879 EHDSGVVTV--ELEPPCRFVIDTPTGPQIKYLYFVKNLNNLRRGAVLGYIGATVRLQAGK 3936
Query 4257 ATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANM 4316
TE +NS +L+ C+FAVD A AY D + G +P+ NCVKML +G+GQAIT T ++N
Sbjct 3937 QTEFVSNSHLLTHCSFAVDPAAAYLDAVKQGAKPVGNCVKMLTNGSGSGQAITCTIDSNT 3996
Query 4317 DQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMW 4376
Q+++GGAS C+YCR H+ HP GFC KGK+VQ+P NDP+ F L+NTVC VCG W
Sbjct 3997 TQDTYGGASVCIYCRAHVAHPTMDGFCQYKGKWVQVPIG-TNDPIRFCLENTVCKVCGCW 4055
Query 4377 KGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAG 4436
+GC+CD+ +QS D S+LNRV G SAARL PC GT D RAFD+YN +
Sbjct 4056 LNHGCTCDR---TAIQSFD-NSYLNRVRGSSAARLEPC-NGTDIDYCVRAFDVYNKDASF 4110
Query 4437 FAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKF 4496
K LK+NC RF+ D+D D++++VKR S HE+++YNLLK C AVAKHDFF +
Sbjct 4111 IGKNLKSNCVRFKNVDKD----DAFYIVKRCIKSVMDHEQSMYNLLKGCNAVAKHDFFTW 4166
Query 4497 RIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYD 4556
+ ++SRQ LTKYTM DL +ALR+FDE +C+ KEILV CC DYF K+W+D
Sbjct 4167 HEGRTIYGNVSRQDLTKYTMMDLCFALRNFDEKDCEVFKEILVLTGCCSTDYFEMKNWFD 4226
Query 4557 FVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQ 4616
+EN DI RVYA LG+ V A+LK V FCD M G+VGVLTLDNQDLNGN+YDFGDF+
Sbjct 4227 PIENEDIHRVYAALGKVVANAMLKCVAFCDEMVLKGVVGVLTLDNQDLNGNFYDFGDFVL 4286
Query 4617 TTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDL-TKPYIKWDLLKYDFTEERLKLF 4675
PG G+P SYYS +MP++ +T L +E + +D+ + + +DLLKYDFTE + LF
Sbjct 4287 CPPGMGIPYCTSYYSYMMPVMGMTNCLASECFMKSDIFGQDFKTFDLLKYDFTEHKEVLF 4346
Query 4676 DRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVS 4735
++YFKYW Q YHP+CV+C D+ CILHC+NFN LF+T P T+FGPL RK+F+DGVP V +
Sbjct 4347 NKYFKYWGQDYHPDCVDCHDEMCILHCSNFNTLFATTIPNTAFGPLCRKVFIDGVPVVAT 4406
Query 4736 TGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTN 4795
GYHF++LG+V N+DVN HS+RL+ ELL + DP + AS L+DKRT CFSVAAL+
Sbjct 4407 AGYHFKQLGLVWNKDVNTHSTRLTITELLQFVTDPTLIVASSPALVDKRTVCFSVAALST 4466
Query 4796 NVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTM 4855
+ QTVKPG+FNK+FYDF S+GFF EGS + LKHFFF Q G+AAI D+DYYRYN PTM
Sbjct 4467 GLTSQTVKPGHFNKEFYDFLRSQGFFDEGSELTLKHFFFTQKGDAAIKDFDYYRYNRPTM 4526
Query 4856 CDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYED 4915
DI Q +V +YFDCY+GGCI + +V+V NL+KSAG+P NK+GKA LYY+S+SYE+
Sbjct 4527 LDIGQARVAYQVAARYFDCYEGGCITSREVVVTNLNKSAGWPLNKFGKAGLYYESISYEE 4586
Query 4916 QDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATR 4975
QDA+F+ TKRN++PT+TQ+NLKYAIS K RARTV GVS+ +TMT RQFHQK LKSI ATR
Sbjct 4587 QDAIFSLTKRNILPTMTQLNLKYAISGKERARTVGGVSLLATMTTRQFHQKCLKSIVATR 4646
Query 4976 GATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHT 5035
ATVVIGT+KFYGGW NMLK + +DV++P LMGWDYPKCDRAMP+M+R++++++L KH
Sbjct 4647 NATVVIGTTKFYGGWDNMLKNLMADVDDPKLMGWDYPKCDRAMPSMIRMLSAMILGSKHV 4706
Query 5036 TCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTAN 5095
TCC+ S +FYRL+NE AQVL+E+V G Y KPGGT+SGDATTAYANSVFNI QAV++N
Sbjct 4707 TCCTASDKFYRLSNELAQVLTEVVYSNGGFYFKPGGTTSGDATTAYANSVFNIFQAVSSN 4766
Query 5096 VNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAV 5155
+N +LS + + + V+ LQ +LY+ YRN +VD FV++FY YL+KHFSMMILSDD+V
Sbjct 4767 INCVLSVNSSNCNNFNVKKLQRQLYDNCYRNSNVDESFVDDFYGYLQKHFSMMILSDDSV 4826
Query 5156 VCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQG 5215
VC+N TYA G +A I FK+ LYYQN VFMS AKCWTE DL+ GPHEFCSQHTM +
Sbjct 4827 VCYNKTYAGLGYIADISAFKATLYYQNGVFMSTAKCWTEEDLSIGPHEFCSQHTMQIVDE 4886
Query 5216 DDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHL 5275
+ YLPYPDPSRI+ AG FVDDI KTD +++ER+VSLAIDAYPL+KHP EY VF+
Sbjct 4887 NGKYYLPYPDPSRIISAGVFVDDITKTDAVILLERYVSLAIDAYPLSKHPKPEYRKVFYA 4946
Query 5276 YLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQ 5335
L +++ L+ L +L+ +SV L +++ S++W+ FY +MY TVLQA G CV+C SQ
Sbjct 4947 LLDWVKHLNKTLNEGVLESFSVTLLDEHESKFWDESFYASMYEKSTVLQAAGLCVVCGSQ 5006
Query 5336 TSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYY 5395
T LRCG C+RRP LC KC YDHV T HK +L++ PYVCN GC+V DVT+LYLGG++YY
Sbjct 5007 TVLRCGDCLRRPMLCTKCAYDHVFGTDHKFILAITPYVCNTSGCNVNDVTKLYLGGLNYY 5066
Query 5396 CKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLK 5455
C HKP +SFPLC+ G VFGLYK++ +GS ++ FN ++T DW++ DY LAN E L+
Sbjct 5067 CVDHKPHLSFPLCSAGNVFGLYKSSALGSMDIDVFNKLSTSDWSDIRDYKLANDAKESLR 5126
Query 5456 LFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNS 5515
LFAAET+KA EE+ K SY AT++E++ +EL L WE GK +PPLNRN VFT +++TK+S
Sbjct 5127 LFAAETVKAKEESVKSSYAYATLKEIVGPKELLLLWESGKAKPPLNRNSVFTCFQITKDS 5186
Query 5516 KVQIGEYTFEKGDYG-DAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRIT 5574
K Q+GE+ FEK DYG D V Y+ T T KL G F+LTSH V PL APT+ QE Y I
Sbjct 5187 KFQVGEFVFEKVDYGSDTVTYKSTATTKLVPGMLFILTSHNVAPLRAPTMANQEKYSTIY 5246
Query 5575 GLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACS 5634
L+P+ N+SD +++ V YQ +G Q+ +T+QGPPG+GKSH +IG+ +YYP ARIV+TACS
Sbjct 5247 KLHPSFNVSDAYANLVPYYQLIGKQRITTIQGPPGSGKSHCSIGIGVYYPGARIVFTACS 5306
Query 5635 HAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADI 5694
HAAVD+LC KA+ +DKC+RIIPARARVEC+ FK N+ QYVF TVNALPE ADI
Sbjct 5307 HAAVDSLCAKAVTAYSVDKCTRIIPARARVECYSGFKPNNNSAQYVFSTVNALPEVNADI 5366
Query 5695 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK 5754
VV DE+SM TNYDLSV+N R+ KH VY+GDP QLPAPR L++KG +EP +N V + M
Sbjct 5367 VVVDEVSMCTNYDLSVINQRISYKHIVYVGDPQQLPAPRVLISKGVMEPIDYNVVTQRMC 5426
Query 5755 TIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINR 5814
IGPD+FL C RCPAEIV+TVS LVY+NK K+ S QCFK+F +G + D S+INR
Sbjct 5427 AIGPDVFLHKCYRCPAEIVNTVSELVYENKFVPVKEASKQCFKIFERGSVQVDNGSSINR 5486
Query 5815 PQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTT 5874
Q+ VV+ F+ +N W KAVFISPYNSQN VA+++LGL TQTVDS+QGSEYDYVIF QT+
Sbjct 5487 RQLDVVKRFIHKNSTWSKAVFISPYNSQNYVAARLLGLQTQTVDSAQGSEYDYVIFAQTS 5546
Query 5875 ETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFK 5934
+TAH+CN NRFNVAITRAK GI CIMSDR L+D L+F + + LQ+E+ GLFK
Sbjct 5547 DTAHACNANRFNVAITRAKKGIFCIMSDRTLFDALKFFEITM-----TDLQSESSCGLFK 5601
Query 5935 DCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGY 5994
DC++ L P+ A T+LS+ +FKT G G TY +IS MGF+ + + G
Sbjct 5602 DCARNPIDLPPSHATTYLSLSDRFKTSGDLAVQIGNNNVCTYEHVISYMGFRFDVSMPGS 5661
Query 5995 PNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPN 6054
++F TR+ A+RHVR W+G DVEG H T + VGTN+PLQ+GFS GV+ VA P G V T
Sbjct 5662 HSLFCTRDFAMRHVRGWLGMDVEGAHVTGDNVGTNVPLQVGFSNGVDFVAQPEGCVLTNT 5721
Query 6055 NTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHG 6114
+ V A+ PPG+QF H++PL+ KG PW+V+R +IVQM++D L SD +VFVLWA G
Sbjct 5722 GSVVKPVRARAPPGEQFTHIVPLLRKGQPWSVLRKRIVQMIADFLAGSSDVLVFVLWAGG 5781
Query 6115 FELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGF 6174
ELT+M+YFVKIG + C C ATC+++ S+ Y C+ H++G DYVYNP++ID+QQWG+
Sbjct 5782 LELTTMRYFVKIGAVKHC-QCGTVATCYNSVSNDYCCFKHALGCDYVYNPYVIDIQQWGY 5840
Query 6175 TGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAAC 6234
G+L +NH C VH N HVAS DAIMTRCLAV++CFVK VDW+I YP+I +E IN
Sbjct 5841 VGSLSTNHHAICNVHRNEHVASGDAIMTRCLAVYDCFVKNVDWSITYPMIANENAINKGG 5900
Query 6235 RKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYS 6294
R VQ +++AA+ +HDIGNPK I+C D +W YD P + +E Y
Sbjct 5901 RTVQSHIMRAAIKLYNPKAIHDIGNPKGIRCA-VTDAKWYCYDKNPINSNVKTLE---YD 5956
Query 6295 YATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTP 6354
Y TH DG+CLFWNCNVD YP SIVCRFDTR S LNL G +GGSLYVN HAFHTP
Sbjct 5957 YMTHGQ--MDGLCLFWNCNVDMYPEFSIVCRFDTRTRSTLNLEGVNGGSLYVNNHAFHTP 6014
Query 6355 AFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHAN 6414
A+DK A LK PFFYY D CE ++YVPL++ CIT+CN+GGAVC HAN
Sbjct 6015 AYDKRAMAKLKPAPFFYYDDGSCEVVH----DQVNYVPLRATNCITKCNIGGAVCSKHAN 6070
Query 6415 EYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFT--RLQSLENVAFNVVNKGHFDGQQG 6472
YR Y+++YN+ AGF++WV FD YNLW TFT LQ LEN+AFNVVNKG F G G
Sbjct 6071 LYRAYVESYNIFTQAGFNIWVPTTFDCYNLWQTFTEVNLQGLENIAFNVVNKGSFVGADG 6130
Query 6473 EVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIA 6532
E+PV+I + V+ + D +F NKT+LP N+AFEL+AKR + P + IL NLGV
Sbjct 6131 ELPVAISGDKVFVRDGNTDNLVFVNKTSLPTNIAFELFAKRKVGLTPPLSILKNLGVVAT 6190
Query 6533 ANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNG 6592
V+WDY+ + P T VC TD A + +D + G + F + N
Sbjct 6191 YKFVLWDYEAERPLTSFTKSVCGYTDFA--------EDVCTCYDNSIQGSYERFTLSTNA 6242
Query 6593 VLITEGSVK---GLQPSVGPKQASLNGVTLI------GEAVKTQFNYYKKVDGVVQQLPE 6643
VL + +VK P++ LNG + G + Y + DG +
Sbjct 6243 VLFSATAVKTGGKSLPAIKLNFGMLNGNAIATVKSEDGNIKNINWFVYVRKDGKPVDHYD 6302
Query 6644 TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLL 6703
++TQ RNLQ+F PRS ME DFL + + FI++Y LE + FEH+VYGD S + LGGLHLL
Sbjct 6303 GFYTQGRNLQDFLPRSTMEEDFLNMDIGVFIQKYGLEDFNFEHVVYGDVSKTTLGGLHLL 6362
Query 6704 IGLAKRFKESPFELEDFI-PMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQD 6762
I + K + E+F+ D T+K +T SSK VC+ +DLLLDDFV ++KS D
Sbjct 6363 ISQVRLSKMGILKAEEFVAASDITLKCCTVTYLNDPSSKTVCTYMDLLLDDFVSVLKSLD 6422
Query 6763 LSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEK 6822
L+VVSKV +V ID +MLWCKD V TFYP+LQS++ W+ G +MP +YK QRM LE
Sbjct 6423 LTVVSKVHEVIIDNKPWRWMLWCKDNAVATFYPQLQSAE-WKCGYSMPGIYKTQRMCLEP 6481
Query 6823 CDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAV 6882
C+L NYG LP GIM NV KYTQLCQY N+ TL VP+NMRV+H GAGSD GVAPGTAV
Sbjct 6482 CNLYNYGAGLKLPSGIMFNVVKYTQLCQYFNSTTLCVPHNMRVLHLGAGSDYGVAPGTAV 6541
Query 6883 LRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKEND 6942
L++WLP ++VD+D+ D+VSDAD ++ GDCATV+ +K+DL+ISDMYD +TK + EN
Sbjct 6542 LKRWLPHDAIVVDNDVVDYVSDADFSVTGDCATVYLEDKFDLLISDMYDGRTKAIDGENV 6601
Query 6943 SKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEA 7002
SKEGFFTYI GFI +KLA+GGS+AIK+TE+SWN LY+L+ F++WT F T+VN SSSEA
Sbjct 6602 SKEGFFTYINGFICEKLAIGGSIAIKVTEYSWNKKLYELVQRFSFWTMFCTSVNTSSSEA 6661
Query 7003 FLIGCNYLGKPREQ--IDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSL 7060
F++G NYLG + IDG ++HANY+FWRN+ + LS S+ D+SKF K + T V+ L
Sbjct 6662 FVVGINYLGDFAQGPFIDGNIIHANYVFWRNSTVMSLSYNSVLDLSKFNCKHKATVVVQL 6721
Query 7061 KEGQINDMILSLLSKGRLIIRENNRVVISSDVLVNN 7096
K+ IN+M+LSL+ G+L++R N + + S+ LV+
Sbjct 6722 KDSDINEMVLSLVRSGKLLVRGNGKCLSFSNHLVST 6757
Score = 257 bits (656), Expect = 4e-66, Method: Composition-based stats.
Identities = 125/768 (16%), Positives = 262/768 (34%), Gaps = 67/768 (9%)
Query 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK-QV 1199
+ +S G + + +S +CVD N + L + + V
Sbjct 1193 CSSIFRGAVSCGHYQTNI-YSQNLCVDGFGVNKIQPWTNDALNTICIKDADYNAKVEISV 1251
Query 1200 EQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLE---ETKFLTENLLLY 1256
+ + F+ + K + + + V+ V ++ ENL
Sbjct 1252 TPIKNTVDTTPKEEFVVKEKLNAFLVHDNVAFYQGDVDTVVNGVDFDFIVNAANENLAHG 1311
Query 1257 IDINGNLHPDSATLVSDIDITFLKKDAPYIVGD-VVQEGVLTAV--VIPTKKAGGTTEML 1313
+ L + + + + VG V+ E + V+ +K ++L
Sbjct 1312 GGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTGVMVECDSLRIFNVVGPRKGKHERDLL 1371
Query 1314 AKALRKVPTDN--YITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTV 1371
KA + + +T G+ G +E + VL + + + + V
Sbjct 1372 IKAYNTINNEQGTPLTPILSCGIFGIKLETSLEVLLDVCNTKEV---KVFVYTDTEVCKV 1428
Query 1372 SWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTV 1431
+ ++ + + + VS I+ + + VD ++
Sbjct 1429 KDFVSGLVNVQKVEQPKI-----EPKPVSVIK-----VAPKPYRVDGKFSYF-------T 1471
Query 1432 ASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLT 1491
L+ +D + +V + L L++ + + + +S + D V +
Sbjct 1472 EDLLCVADD--KPIVL----FTDSMLTLDDRGLALDN-ALSGVLSAAIKDCVDINKAIPS 1524
Query 1492 SS-SKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEV 1550
+ K + + + S KD + + + V L
Sbjct 1525 GNLIKFDIGSVVVYMCVVPSEKDKHLDNNVQRCTRKLNRLMCDIVCTIPADYILPLVLSS 1584
Query 1551 ITFD-NLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKP 1609
+T + + L E + I + T D +N+H V ++ QQ G D++ P
Sbjct 1585 LTCNVSFVGELKAAEAKVITIKVTEDGVNVHDVTVTTDKSFEQQVGVIADKDKDLSGAVP 1644
Query 1610 HNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTK-KWKYPQVNGLTSIK 1668
+ + + + V+ E+Y D + ++H+ ++ VNG+ +K
Sbjct 1645 SDLNTSELL-----TKAIDVDWVEFYGFKD----AVTFATVDHSAFAYESAVVNGIRVLK 1695
Query 1669 WADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDV 1728
+DNNC++ + LQ + F L A+ + G+ F A + G+ GD
Sbjct 1696 TSDNNCWVNAVCIALQYSKPHFISQGLDAAWNKFVLGDVEIFVAFVYYVARLMKGDKGDA 1755
Query 1729 RETMSYLFQH-ANLDSCKRVLNVVCKTCGQQ-QTTLKGVEAVMYMGTLSYEQFKKGVQIP 1786
+T++ L ++ AN + C C + + ++ + + + ++ + + G
Sbjct 1756 EDTLTKLSKYLANEAQVQLEHYSSCVECDAKFKNSVASINSAIVCASVKRDGVQVGY--- 1812
Query 1787 CTCGKQATKYLVQQESPFVMMSA----PPAQYELKHGTFTCASEYTGNYQCGHYK-HITS 1841
C G + + +++S P AQ L G A ++G GHY + T+
Sbjct 1813 CVHGIKYYSRVRSVRGRAIIVSVEQLEPCAQSRLLSGVAYTA--FSGPVDKGHYTVYDTA 1870
Query 1842 KETLYCIDGALLTKSSEYKGPITDVF----YKENSYTTTIKPVTYKLD 1885
K+++Y DG K +T V Y T KPV +LD
Sbjct 1871 KKSMY--DGDRFVKHDLSLLSVTSVVMVGGYVAPVNTVKPKPVINQLD 1916
Score = 184 bits (468), Expect = 3e-44, Method: Composition-based stats.
Identities = 69/249 (28%), Positives = 108/249 (43%), Gaps = 16/249 (6%)
Query 991 QDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLK--------LTDNVYIKN 1042
Q + D T + ++E+ +TP+ T++ ++ + DNV
Sbjct 1226 QPWTNDALNTICIKDADYNAKVEISVTPIKNTVDTTPKEEFVVKEKLNAFLVHDNVAFYQ 1285
Query 1043 ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGS 1102
D+ V +VNAAN L HGGG+A AL+ T +Q S ++I G +KVG
Sbjct 1286 GDVDTVVNGVDFDFIVNAANENLAHGGGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTG 1345
Query 1103 CVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSL 1162
++ +L +VVGP K E L+K+ N+ L P+LS GIFG SL
Sbjct 1346 VMVECDSL--RIFNVVGPRKGKHERDLLIKAYNTINNEQGTPLTPILSCGIFGIKLETSL 1403
Query 1163 RVCVDTVRTN-VYLAVFDKNLYDK---LVSSFLEMKSEKQ--VEQKIAEIPKEEVKPFIT 1216
V +D T V + V+ K VS + ++ +Q +E K + K KP+
Sbjct 1404 EVLLDVCNTKEVKVFVYTDTEVCKVKDFVSGLVNVQKVEQPKIEPKPVSVIKVAPKPYRV 1463
Query 1217 ESKPSVEQR 1225
+ K S
Sbjct 1464 DGKFSYFTE 1472
Score = 100 bits (249), Expect = 8e-19, Method: Composition-based stats.
Identities = 58/271 (21%), Positives = 102/271 (38%), Gaps = 24/271 (9%)
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
+ ++NGL +K DNNC++ + +L +Q + A+Q + G A
Sbjct 1037 PFEELNGLKILKQLDNNCWVNSVMLQIQLTGILDGDYAMQF----FKMGRVAKMIERCYT 1092
Query 1717 YCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSY 1776
G +GDV M L + +L + V++ C +C + G AV++ T +
Sbjct 1093 AEQCIRGAMGDVGLCMYRLLK--DLHTGFMVMDYKC-SCTSGRLEESG--AVLFC-TPTK 1146
Query 1777 EQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTF--TCASEYTGNYQCG 1834
+ F C + Q + + + P C+S + G CG
Sbjct 1147 KAF--PYGTCLNCNAPRMCTIRQLQGTIIFVQQKPEPVNPVSFVVKPVCSSIFRGAVSCG 1204
Query 1835 HYKHITSKETLYCIDGALLTKSSEY------KGPITDVFYKENSYTTTIKPVTYKLDGVV 1888
HY+ + L C+DG + K + I D Y ++ P+ +D
Sbjct 1205 HYQTNIYSQNL-CVDGFGVNKIQPWTNDALNTICIKDADYNAKVE-ISVTPIKNTVDTTP 1262
Query 1889 CTE--IDPKLDNYYKKDNSYFTEQPIDLVPN 1917
E + KL+ + DN F + +D V N
Sbjct 1263 KEEFVVKEKLNAFLVHDNVAFYQGDVDTVVN 1293
Score = 60.1 bits (144), Expect = 1e-06, Method: Composition-based stats.
Identities = 83/540 (15%), Positives = 164/540 (30%), Gaps = 69/540 (13%)
Query 171 RELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYC 230
+++ GG Y D CG DG P+ S L + +D +
Sbjct 101 FDVVFGKRGGGNVTYTDQYLCGADGKPV------------MSEDLWQFVDHFGENEEIII 148
Query 231 CREHEHEIAWYTERSEKSYELQTPFEIKLAKKF--DTFNGECPNFVFPLNSIIKTIQPRV 288
H + AW T+R Y+ Q I+ + D + V + +KT V
Sbjct 149 -NGHTYVCAWLTKRKPLDYKRQNNLAIEEIEYVHGDALHTLRNGSVLEMAKEVKTSSKVV 207
Query 289 EKKKLDGFMGRIRSVYPVASPNE----CNQMCLSTLMKCDHCGETSWQTGDFVKATCEFC 344
LD S N + +S L++C CG SW GD+
Sbjct 208 LSDALDKLYKVFGSPVMTNGSNILEAFTKPVFISALVQCT-CGTKSWSVGDWTG------ 260
Query 345 GTENLTKEGATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTI 404
++C + N + + V P ++ T + G
Sbjct 261 --------FKSSCCNVISNKLCVVP------GNVKPGDAVI---------TTQQAGAGIK 297
Query 405 AFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIV 464
F G +V + W A ++ C E +N + N+
Sbjct 298 YFCGMTLKFVANIEGVSVWRVIALQSVDCFVASSTFVEEEHVNR-------MDTFCFNVR 350
Query 465 GDFKLNEEIAIILASFSAST-----SAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKG 519
+A++ A +++ S ++ G + + I + V K + G
Sbjct 351 NSVTDECRLAMLGAEMTSNVRRQVASGVIDISTGW-FDVYDDIFAESKPWFVRKAEDIFG 409
Query 520 AWNIGEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYS-- 577
S L L E R V+SI + + ++++L L+ +
Sbjct 410 PC-WSALASALKQLKVTTGELVRFVKSICNSAVAVVGGTIQILASVPEKFLNAFDVFVTA 468
Query 578 -LRLIDAMMFTSDLAT---NNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEE 633
+ D + T +A + + + +V+L + L + K+K +
Sbjct 469 IQTVFDCAVETCTIAGKAFDKVFDYVLLDNALVKLVTTKLKGVRERGLNKVKYATVVVGS 528
Query 634 KFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSI 693
+ + ++ + + G V +F+L+ ++ ++
Sbjct 529 TEEVKSSRVERSTAVLTIANNYSKLFDEGYTVVIGDVAYFVSDGYFRLMASPNSVLTTAV 588
>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729
Score = 6758 bits (17534), Expect = 0.0, Method: Composition-based stats.
Identities = 2268/5013 (45%), Positives = 3099/5013 (62%), Gaps = 165/5013 (3%)
Query 2110 PNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYM 2169
++LS + + G N TI + ++K+ + N +
Sbjct 1855 SSDLSTLAVTAIVVVGGCVTSN---VPTIVSEKISVMDKLDTGAQKFFQ--FGDFVMNNI 1909
Query 2170 PYFFTLLLQLCTFTRST----NSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSK 2225
F T LL + + R++ + ++ A P +S K+ + ++ +K
Sbjct 1910 VLFLTWLLSMFSLLRTSIMKHDIKVIAKAPKRTGVILTRS-FKYNIRSALFVIKQK---- 1964
Query 2226 LINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGS 2285
+I+ L L ++ + C GY ST YC S
Sbjct 1965 -WCVIV--TLFKFLLLLYAIYALVFMIVQFSPFNSLLCGDIVSGYEKST-FNKDIYCGNS 2020
Query 2286 IPCSVCLSGLDSLDTYPSLETIQITISSF-KWDLTAFGLVAEWFLAYILFTRFFYVLGLA 2344
+ C +CL + + I L F ++ + ++ RF + +A
Sbjct 2021 MVCKMCLFSYQEFNDLDHTSLVWKHIRDPILISLQPFVILVILLIFGNMYLRFGLLYFVA 2080
Query 2345 AIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGC 2404
+ F S+ H W + P + ++ + H++ GC
Sbjct 2081 QFISTFGSFLGFH--QKQWFLHF-------VPFDVLCNEFLATFIVCKIVLFVRHIIVGC 2131
Query 2405 NSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTF 2464
N++ C+ C K R RV TI+NG+ +SFYV ANGG FC HN+ CVNCD+F G+TF
Sbjct 2132 NNADCVACSKSARLKRVPLQTIINGMHKSFYVNANGGTCFCNKHNFFCVNCDSFGPGNTF 2191
Query 2465 ISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNL 2524
I+ ++AR+L K + PT + I+D V NG LY + + S +
Sbjct 2192 INGDIARELGNVVKTAVQPTAPAYVIIDKVDFVNGFYRLYSGDTFWRYDFDITESKYSCK 2251
Query 2525 DNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSA 2584
+ L+ N N IV+ S + K+A VY+SQL+C+PI L++ L+S + S
Sbjct 2252 EVLKNCNV----LENFIVY-NNSGSNITQIKNACVYFSQLLCEPIKLVNSELLSTL--SV 2304
Query 2585 EVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDS 2644
+ + AYV+ ++F ++L ++ AE + ++
Sbjct 2305 DFNGVLHKAYVDVLCNSF---FKELTANMSMAECKATLGLT------------------- 2342
Query 2645 DVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKV-ENMTPRDLGACIDCSARHINAQV 2703
V D V + +H+ D+ ++ S NN+ ++Y K + ++ D+ C+ ++ +N V
Sbjct 2343 -VSDDDFVSAVANAHRYDVLLSDLSFNNFFISYAKPEDKLSVYDIACCMRAGSKVVNHNV 2401
Query 2704 AKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGG 2763
+I ++W VKDF +LS++ +K + K L F LT + + V T I K G
Sbjct 2402 LIKESIPIVWGVKDFNTLSQEGKKYLVKTTKAKGLTFLLTFNDNQAITQVPATSIVAKQG 2461
Query 2764 KIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIAST 2823
+ + V LFV A+F ++ + + T F +K I+ G + +
Sbjct 2462 AGFK---RTYNFLWYVCLFVVALFIGVSFIDYTTTVTSF--HGYDFKYIENGQLKVFEAP 2516
Query 2824 DTCFANKHADFDTWFSQRGGSYT-NDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFL 2882
C N +F+ W + G T N CP++ V R VVPG+P + G L
Sbjct 2517 LHCVRNVFDNFNQWHEAKFGVVTTNSDKCPIVVGVSERI--NVVPGVPTNVYLV--GKTL 2572
Query 2883 HFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGS 2942
F + +CY + C+ + CT + G V YCY+T+++EGS
Sbjct 2573 VFTLQAAFGNTGVCYDFDGVTTSD-----KCIFNSACTRLEGLGGDNV-YCYNTDLIEGS 2626
Query 2943 VAYESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCERSEAGVCVSTS 3001
Y +L+P+ Y + ++FP G +R + T + YCR G C S GVC
Sbjct 2627 KPYSTLQPNAYYKYDAKNYVRFPEILARGFGLRTIRTLATRYCRVGECRDSHKGVCFGFD 2686
Query 3002 GRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLA 3061
+W +N+ R G CG ++LL N+ + + +S ++ + A +T L
Sbjct 2687 -KWYVNDG--RVDDGYICGDGLIDLLVNVLSIFSSSFSVVAMSGHMLFNFLFAAFITFLC 2743
Query 3062 YYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVS 3121
+ +F+R FG+ S+ V L++ +T F +Y+++Y F T +
Sbjct 2744 FLVTKFKRVFGDLSYGVFTVVCATLINNISYVVTQ-NLFFMLLYAILYF--VFTRTVRYA 2800
Query 3122 FLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFNGVSF-STFEE 3177
++ HI ++V + L+P+W+ + S F N K ++ +F G F TFE
Sbjct 2801 WIWHIAYIVAYFLLIPWWLLTWF----SFAAFLELLPNVFKLKISTQLFEGDKFIGTFES 2856
Query 3178 AALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKA 3237
AA TF+L+ Y +L + + + Y A YNKYKY+SG+ YR A HLAKA
Sbjct 2857 AAAGTFVLDMRSYERLINTI--SPEKLKNYAASYNKYKYYSGSASEADYRCACYAHLAKA 2914
Query 3238 LNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD 3297
+ D++ +D+LY PP S S LQSG +KMA PSG VE C+V+V G+T LNG+WL D
Sbjct 2915 MLDYAKDHNDMLYSPPTISYNST-LQSGLKKMAQPSGCVERCVVRVCYGSTVLNGVWLGD 2973
Query 3298 VVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTA 3357
V CPRHVI S +L +Y+ HNF V V L V+G +M VL++KV +
Sbjct 2974 TVTCPRHVIAPSTTVL-IDYDHAYSTMRLHNFSVSHNGVFLGVVGVTMHGSVLRIKVSQS 3032
Query 3358 NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDY 3417
N TPK+ F ++PG +F++LACY G SGV+ +R NFTIKGSF+NG+CGS G+N+
Sbjct 3033 NVHTPKHVFKTLKPGDSFNILACYEGIASGVFGVNLRTNFTIKGSFINGACGSPGYNVRN 3092
Query 3418 -DCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVI 3476
V FCY+H +EL +G H G+D G+ YG F D+ + Q + ++ NV+A+LYAA++
Sbjct 3093 DGTVEFCYLHQIELGSGAHVGSDFTGSVYGNFDDQPSLQVESANLMLSDNVVAFLYAALL 3152
Query 3477 NGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQ 3536
NG RW+L ++ FN AM Y ++ V+ L+A+TG++V + AS++ L
Sbjct 3153 NGCRWWLCSTRVNVDGFNEWAMANGYTSVSS--VECYSILAAKTGVSVEQLLASIQHL-H 3209
Query 3537 NGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQ 3596
G G+ ILG + L DEFT +VV+Q GV QS + I G L ++ ++
Sbjct 3210 EGFGGKNILGYSSLCDEFTLAEVVKQMYGVNLQSG--KVIFGLKTMFLFSVFFTMFWAEL 3267
Query 3597 STQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP 3656
++ ++ P ++ +S MF+KHK FL +FLLP++ A +N V
Sbjct 3268 FI-YTNTIWINPVILTPIFCLLLFLSLVLTMFLKHKFLFLQVFLLPTVIATALYNCVL-- 3324
Query 3657 ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLT 3716
++++ + + S+ ++ V + ++ L T R + + +++
Sbjct 3325 DYYIVKFLADHFNYNVSVLQMDVQGLVNVLVCLFVVFLHTWRFSKERFTHWFTYVCSLIA 3384
Query 3717 LVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTL 3776
+ Y +Y +S+ + + S+ + V L+R IVF E F +
Sbjct 3385 VAYTYFYSGDF---LSLLVMFLCAISSDWYIGAIVFRLSRLIVFFSPE---SVFSVFGDV 3438
Query 3777 QCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSID 3836
+ ++VY GY Y+G+ NR+F+ T+GVYD+ VS EF+YM + GL P D
Sbjct 3439 KLTLVVYLICGYLVCTYWGILYWFNRFFKCTMGVYDFKVSAAEFKYMVANGLHAPHGPFD 3498
Query 3837 AFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHN 3896
A L+ KLLG+GG CIK++TVQSK++D+KCT+VVLL L + + ++S WA CV LHN
Sbjct 3499 ALWLSFKLLGIGGDRCIKISTVQSKLTDLKCTNVVLLGCLSSMNIAANSSEWAYCVDLHN 3558
Query 3897 DILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA 3956
I L D +A +++LL+ LS ++ L + DN +TLQ++AS F S+PSY A
Sbjct 3559 KINLCDDPEKAQSMLLALLAFFLSKHSDFGLDGLIDSYFDNSSTLQSVASSFVSMPSYIA 3618
Query 3957 FATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQA 4016
+ A++AYE A+ANG S ++K+LK+++N+AKSEFD + ++Q+K+ +MA+QA TQMYK+A
Sbjct 3619 YENARQAYEDAIANGSSSQLIKQLKRAMNIAKSEFDHEISVQKKINRMAEQAATQMYKEA 3678
Query 4017 RSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPD 4076
RS ++++KV SAM ++LF MLR+LD ++ ++N ARDG VPL++IP T+A+KL +V PD
Sbjct 3679 RSVNRKSKVISAMHSLLFGMLRRLDMSSVETVLNLARDGVVPLSVIPATSASKLTIVSPD 3738
Query 4077 YNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSA 4136
+Y + YA +W + V D D + V + EI+ +N L WPLI+ R
Sbjct 3739 LESYSKIVCDGSVHYAGVVWTLNDVKDNDGRPVHVKEITKENVETLTWPLILNCER---V 3795
Query 4137 VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARF 4196
VKLQNNE+ P L+Q A D NAL YNT G F+ A +S+ DLK+ ++
Sbjct 3796 VKLQNNEIMPGKLKQKPMKAEGDGGVLGDGNAL--YNTEGGKTFMYAYISNKADLKFVKW 3853
Query 4197 PKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGN 4256
G TI EL+ PCRF+ +TP GP+VKYLYF+K LN L RG VLG + AT+RLQAG
Sbjct 3854 EYEGGCNTI--ELDSPCRFMVETPNGPQVKYLYFVKNLNTLRRGAVLGFIGATIRLQAGK 3911
Query 4257 ATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANM 4316
TE+ NS +L+ CAF+VD A Y + + G +P++NC+KML G GQAIT + +AN
Sbjct 3912 QTELAVNSGLLTACAFSVDPATTYLEAVKHGAKPVSNCIKMLSNGAGNGQAITTSVDANT 3971
Query 4317 DQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMW 4376
+Q+S+GGAS CLYCR H+ HP+ G+C KGK VQ+P C DP+ F L+N VC VCG W
Sbjct 3972 NQDSYGGASICLYCRAHVPHPSMDGYCKFKGKCVQVPIGCL-DPIRFCLENNVCNVCGCW 4030
Query 4377 KGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAG 4436
G+GC+CD+ +QS D S+LNR G SAARL PC GT D RAFDIYN V+
Sbjct 4031 LGHGCACDR---TTIQSVDI-SYLNRARGSSAARLEPC-NGTDIDKCVRAFDIYNKNVSF 4085
Query 4437 FAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKF 4496
K LK NC RF+ D L D YFV+KR T S +HE+++YNLL A+A+HDFF +
Sbjct 4086 LGKCLKMNCVRFKNAD----LKDGYFVIKRCTKSVMEHEQSMYNLLNFSGALAEHDFFTW 4141
Query 4497 RIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYD 4556
+ + ++SR LTKYTM DLVYA+R+FDE NCD LKE+LV CCD+ YF+ K WYD
Sbjct 4142 KDGRVIYGNVSRHNLTKYTMMDLVYAMRNFDEQNCDVLKEVLVLTGCCDNSYFDSKGWYD 4201
Query 4557 FVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQ 4616
VEN DI RVYA+LG+ V +A+LK V CDAM G+VGVLTLDNQDLNGN+YDFGDF+
Sbjct 4202 PVENEDIHRVYASLGKIVARAMLKCVALCDAMVAKGVVGVLTLDNQDLNGNFYDFGDFVV 4261
Query 4617 TTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDL-TKPYIKWDLLKYDFTEERLKLF 4675
+ P GVP SYYS +MPI+ LT L +E V +D+ + +DLLKYDFTE + LF
Sbjct 4262 SLPNMGVPCCTSYYSYMMPIMGLTNCLASECFVKSDIFGSDFKTFDLLKYDFTEHKENLF 4321
Query 4676 DRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVS 4735
++YFK+W YHPNC +C DD C++HCANFN LF+T P T+FGPL RK+F+DGVP V +
Sbjct 4322 NKYFKHWSFDYHPNCSDCYDDMCVIHCANFNTLFATTIPGTAFGPLCRKVFIDGVPLVTT 4381
Query 4736 TGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTN 4795
GYHF++LG+V N+DVN HS RL+ ELL + DP++ AS L+D+RT CFSVAAL+
Sbjct 4382 AGYHFKQLGLVWNKDVNTHSVRLTITELLQFVTDPSLIIASSPALVDQRTICFSVAALST 4441
Query 4796 NVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTM 4855
+ Q VKPG+FN++FY+F +GFF EGS + LKHFFFAQ+G+AA+ D+D+YRYN PT+
Sbjct 4442 GLTNQVVKPGHFNEEFYNFLRLRGFFDEGSELTLKHFFFAQNGDAAVKDFDFYRYNKPTI 4501
Query 4856 CDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYED 4915
DI Q ++V +YFD Y+GGCI A +V+V NL+KSAG+P NK+GKA LYY+S+SYE+
Sbjct 4502 LDICQARVTYKIVSRYFDIYEGGCIKACEVVVTNLNKSAGWPLNKFGKASLYYESISYEE 4561
Query 4916 QDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATR 4975
QDALFA TKRNV+PT+TQ+NLKYAIS K RARTV GVS+ STMT RQ+HQK LKSI TR
Sbjct 4562 QDALFALTKRNVLPTMTQLNLKYAISGKERARTVGGVSLLSTMTTRQYHQKHLKSIVNTR 4621
Query 4976 GATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHT 5035
ATVVIGT+KFYGGW+NML+T+ VENP LMGWDYPKCDRA+PNM+R+++++VL KH
Sbjct 4622 NATVVIGTTKFYGGWNNMLRTLIDGVENPMLMGWDYPKCDRALPNMIRMISAMVLGSKHV 4681
Query 5036 TCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTAN 5095
CC+ + RFYRL NE AQVL+E+V G Y KPGGT+SGDA+TAYANS+FNI QAV++N
Sbjct 4682 NCCTATDRFYRLGNELAQVLTEVVYSNGGFYFKPGGTTSGDASTAYANSIFNIFQAVSSN 4741
Query 5096 VNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAV 5155
+N LLS + + VR+LQ RLY+ YR V+ F++++Y YLRKHFSMMILSDD V
Sbjct 4742 INRLLSVPSDSCNNVNVRDLQRRLYDNCYRLTSVEESFIDDYYGYLRKHFSMMILSDDGV 4801
Query 5156 VCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQG 5215
VC+N YA G +A I FK+ LYYQNNVFMS +KCW E DLTKGPHEFCSQHTM +
Sbjct 4802 VCYNKDYAELGYIADISAFKATLYYQNNVFMSTSKCWVEEDLTKGPHEFCSQHTMQIVDK 4861
Query 5216 DDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHL 5275
D YLPYPDPSRIL AG FVDD+VKTD +++ER+VSLAIDAYPL+KHPN EY VF++
Sbjct 4862 DGTYYLPYPDPSRILSAGVFVDDVVKTDAVVLLERYVSLAIDAYPLSKHPNSEYRKVFYV 4921
Query 5276 YLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQ 5335
L +++ L+ L +L+ +SV L ++ ++W +FY +MY T+LQA G CV+C SQ
Sbjct 4922 LLDWVKHLNKNLNEGVLESFSVTLLDNQEDKFWCEDFYASMYENSTILQAAGLCVVCGSQ 4981
Query 5336 TSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYY 5395
T LRCG C+R+P LC KC YDHV T HK +L++ PYVCNA GC V+DV +LYLGG++YY
Sbjct 4982 TVLRCGDCLRKPMLCTKCAYDHVFGTDHKFILAITPYVCNASGCGVSDVKKLYLGGLNYY 5041
Query 5396 CKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLK 5455
C +HKP +SFPLC+ G +FGLYKN+ GS +V FN +AT DWT+ DY LAN + L+
Sbjct 5042 CTNHKPQLSFPLCSAGNIFGLYKNSATGSLDVEVFNRLATSDWTDVRDYKLANDVKDTLR 5101
Query 5456 LFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNS 5515
LFAAET+KA EE+ K SY AT++EV+ +EL LSWE GK +PPLNRN VFT ++++K+S
Sbjct 5102 LFAAETIKAKEESVKSSYAFATLKEVVGPKELLLSWESGKVKPPLNRNSVFTCFQISKDS 5161
Query 5516 KVQIGEYTFEKGDYG-DAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRIT 5574
K QIGE+ FEK +YG D V Y+ T T KL G FVLTSH V PL APT+ QE Y I
Sbjct 5162 KFQIGEFIFEKVEYGSDTVTYKSTVTTKLVPGMIFVLTSHNVQPLRAPTIANQEKYSSIY 5221
Query 5575 GLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACS 5634
L+P N+SD +++ V YQ +G QK +T+QGPPG+GKSH +IGL LYYP ARIV+ AC+
Sbjct 5222 KLHPAFNVSDAYANLVPYYQLIGKQKITTIQGPPGSGKSHCSIGLGLYYPGARIVFVACA 5281
Query 5635 HAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADI 5694
HAAVD+LC KA+ IDKC+RIIPARARVEC+ FK N+T QY+F TVNALPE ADI
Sbjct 5282 HAAVDSLCAKAMTVYSIDKCTRIIPARARVECYSGFKPNNTSAQYIFSTVNALPECNADI 5341
Query 5695 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK 5754
VV DE+SM TNYDLSV+N RL KH VY+GDP QLPAPR ++TKG +EP +N V + M
Sbjct 5342 VVVDEVSMCTNYDLSVINQRLSYKHIVYVGDPQQLPAPRVMITKGVMEPVDYNVVTQRMC 5401
Query 5755 TIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINR 5814
IGPD+FL C RCPAEIV+TVS LVY+NK K S QCFK+F+KG + D S+INR
Sbjct 5402 AIGPDVFLHKCYRCPAEIVNTVSELVYENKFVPVKPASKQCFKVFFKGNVQVDNGSSINR 5461
Query 5815 PQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTT 5874
Q+ +V+ FL +NP+W KAVFISPYNSQN VAS+ LGL QTVDSSQGSEYDYVI+ QT+
Sbjct 5462 KQLEIVKLFLVKNPSWSKAVFISPYNSQNYVASRFLGLQIQTVDSSQGSEYDYVIYAQTS 5521
Query 5875 ETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFK 5934
+TAH+CNVNRFNVAITRAK GI C+M D+ L+D L+F ++ A L + V GLFK
Sbjct 5522 DTAHACNVNRFNVAITRAKKGIFCVMCDKTLFDSLKFFEIK-----HADLHSSQVCGLFK 5576
Query 5935 DCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGY 5994
+C++ L PT A T LS+ +FKT G G TY +IS MGF+ + + G
Sbjct 5577 NCTRTPLNLPPTHAHTFLSLSDQFKTTGDLAVQIGSNNVCTYEHVISFMGFRFDISIPGS 5636
Query 5995 PNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPN 6054
++F TR+ AIR+VR W+G DVE H + +GTN+PLQ+GFS GVN V G V T
Sbjct 5637 HSLFCTRDFAIRNVRGWLGMDVESAHVCGDNIGTNVPLQVGFSNGVNFVVQTEGCVSTNF 5696
Query 6055 NTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHG 6114
V AK PPG+QF+HLIPL+ KG PW +VR +IVQM+SD L NLSD +VFVLWA
Sbjct 5697 GDVIKPVCAKSPPGEQFRHLIPLLRKGQPWLIVRRRIVQMISDYLSNLSDILVFVLWAGS 5756
Query 6115 FELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGF 6174
ELT+M+YFVKIGP + C C ATC+++ S+ Y C+ H++G DYVYNP+ D+QQWG+
Sbjct 5757 LELTTMRYFVKIGPIKYC-YCGNSATCYNSVSNEYCCFKHALGCDYVYNPYAFDIQQWGY 5815
Query 6175 TGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAAC 6234
G+L NH +C +H N H AS DA+MTRCLAVH+CFVK VDWT+ YP I +E IN
Sbjct 5816 VGSLSQNHHTFCNIHRNEHDASGDAVMTRCLAVHDCFVKNVDWTVTYPFIANEKFINGCG 5875
Query 6235 RKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYS 6294
R VQ VV+AAL K V+HDIGNPK ++C D +W YD QP + L Y
Sbjct 5876 RNVQGHVVRAALKLYKPSVIHDIGNPKGVRCA-VTDAKWYCYDKQPVNSNVK---LLDYD 5931
Query 6295 YATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTP 6354
YATH DG+CLFWNCNVD YP SIVCRFDTR S NL G +GGSLYVNKHAFHTP
Sbjct 5932 YATHGQ--LDGLCLFWNCNVDMYPEFSIVCRFDTRTRSVFNLEGVNGGSLYVNKHAFHTP 5989
Query 6355 AFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHAN 6414
A+DK AFV LK +PFFY+ DS C+ ++YVPL++++C+TRCN+GGAVC HAN
Sbjct 5990 AYDKRAFVKLKPMPFFYFDDSDCDVVQ----EQVNYVPLRASSCVTRCNIGGAVCSKHAN 6045
Query 6415 EYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF--TRLQSLENVAFNVVNKGHFDGQQG 6472
Y+ Y++AYN AGF++WV FD YNLW F T LQSLEN+AFNVV KG F G G
Sbjct 6046 LYQKYVEAYNTFTQAGFNIWVPHSFDVYNLWQIFIETNLQSLENIAFNVVKKGCFTGVDG 6105
Query 6473 EVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIA 6532
E+PV+++N+ V+ + VD +F NKTTLP NVAFEL+AKR + P + IL NLGV
Sbjct 6106 ELPVAVVNDKVFVRYGDVDNLVFTNKTTLPTNVAFELFAKRKMGLTPPLSILKNLGVVAT 6165
Query 6533 ANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNG 6592
V+WDY+ + P T VC TD + V FD + G + F N
Sbjct 6166 YKFVLWDYEAERPFTSYTKSVCKYTDFN--------EDVCVCFDNSIQGSYERFTLTTNA 6217
Query 6593 VLITEGSVKGLQPSVGPKQASLNGVTL------IGEAVKTQFNYYKKVDGVVQQLPETYF 6646
VL + +K L P + LNG+ + G + Y + +G Q + ++
Sbjct 6218 VLFSTVVIKNLTP-IKLNFGMLNGMPVSSIKGDKGVEKLVNWYIYVRKNGQFQDHYDGFY 6276
Query 6647 TQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGL 6706
TQ RNL +F PRS ME DFL + M FI +Y LE + FEH+VYGD S + LGGLHLLI
Sbjct 6277 TQGRNLSDFTPRSDMEYDFLNMDMGVFINKYGLEDFNFEHVVYGDVSKTTLGGLHLLISQ 6336
Query 6707 AKRFKESPFELEDFIP-MDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV 6765
+ K + +DF+ D+T++ +T SSK VC+ +DLLLDDFV I+KS DL V
Sbjct 6337 FRLSKMGVLKADDFVTASDTTLRCCTVTYLNELSSKVVCTYMDLLLDDFVTILKSLDLGV 6396
Query 6766 VSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDL 6825
+SKV +V ID +MLWCKD H+ TFYP+LQS++ W+ G AMP +YK+QRM LE C+L
Sbjct 6397 ISKVHEVIIDNKPYRWMLWCKDNHLSTFYPQLQSAE-WKCGYAMPQIYKLQRMCLEPCNL 6455
Query 6826 QNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQ 6885
NYG LP GIM+NV KYTQLCQYLN+ T+ VP+NMRV+H+GAGSDKGVAPGT VL++
Sbjct 6456 YNYGAGIKLPSGIMLNVVKYTQLCQYLNSTTMCVPHNMRVLHYGAGSDKGVAPGTTVLKR 6515
Query 6886 WLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKE 6945
WLP +++D+D+ND+VSDAD ++ GDCATV+ +K+DL+ISDMYD + K EN SK+
Sbjct 6516 WLPPDAIIIDNDINDYVSDADFSITGDCATVYLEDKFDLLISDMYDGRIKFCDGENVSKD 6575
Query 6946 GFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLI 7005
GFFTY+ G I++KLA+GGSVAIKITE+SWN LY+L+ FA+WT F T+VN SSSEAFLI
Sbjct 6576 GFFTYLNGVIREKLAIGGSVAIKITEYSWNKYLYELIQRFAFWTLFCTSVNTSSSEAFLI 6635
Query 7006 GCNYLGKPREQ--IDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEG 7063
G NYLG + I G +HANYIFWRN+ + LS S+ D+SKF K + T V++LK+
Sbjct 6636 GINYLGDFIQGPFIAGNTVHANYIFWRNSTIMSLSYNSVLDLSKFECKHKATVVVTLKDS 6695
Query 7064 QINDMILSLLSKGRLIIRENNRVVISSDVLVNN 7096
+NDM+LSL+ GRL++R N R S+ LV+
Sbjct 6696 DVNDMVLSLIKSGRLLLRNNGRFGGFSNHLVST 6728
Score = 173 bits (438), Expect = 7e-41, Method: Composition-based stats.
Identities = 69/340 (20%), Positives = 123/340 (36%), Gaps = 34/340 (10%)
Query 1544 FHLDGEVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGAD 1603
F ++ V+ ++ + + + T D IN+ VV+ S + G+Q G DG D
Sbjct 1564 FVVESNVMDVNDC------FKNDNVVLKITEDGINVKDVVVESSKSLGKQLGVVS-DGVD 1616
Query 1604 VTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQ--V 1661
S EG + N DT+ A E F + A K + YP V
Sbjct 1617 --------SFEGV---LPINTDTVLSVAPEVDWVAFYGFEKAALFASLDVKPYGYPNDFV 1665
Query 1662 NGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKT 1721
G + DNNC++ + LQ ++ F L + + G+ F + I +
Sbjct 1666 GGFRVLGTTDNNCWVNATCIILQYLKPTFKSKGLNVLWNKFVTGDVGPFVSFIYFITMSS 1725
Query 1722 VGELGDVRETMSYLFQHANLDS-CKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFK 1780
G+ GD E +S L ++ DS C C ++T+ V++ + ++ +
Sbjct 1726 KGQKGDAEEALSKLSEYLISDSIVTLEQYSTCDIC---KSTVVEVKSAIVCASVLKDGCD 1782
Query 1781 KGVQIPCTCGKQATKYLVQQESPFVMMSA----PPAQYELKHGTFTCASEYTGNYQCGHY 1836
G C + + V+ + +L +G ++G++ GHY
Sbjct 1783 VGF---CPHRHKLRSRVKFVNGRVVITNVGEPIISQPSKLLNGIAYT--TFSGSFDNGHY 1837
Query 1837 KHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTT 1876
+ DGA L S +T + T+
Sbjct 1838 V-VYDAANNAVYDGARLFSSDLSTLAVTAIVVVGGCVTSN 1876
Score = 159 bits (402), Expect = 1e-36, Method: Composition-based stats.
Identities = 78/309 (25%), Positives = 126/309 (41%), Gaps = 27/309 (9%)
Query 993 GSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKV 1052
G D + +++ T+ V + ++ EV F+ Y NV DI V
Sbjct 1228 GVFDIKNSSVNTVCFVDVDFH---SVEIEAGEVKPFAVY----KNVKFYLGDISHLVNCV 1280
Query 1053 KPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAK 1112
VVNAAN L HGGGVA A++ T +Q S DYI++NGPLKVG +L
Sbjct 1281 SFDFVVNAANENLLHGGGVARAIDILTEGQLQSLSKDYISSNGPLKVGAGVMLECEKF-- 1338
Query 1113 HCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTN 1172
+ +VVGP K E L+++ ++ + L PLLS GIFG +SL+
Sbjct 1339 NVFNVVGPRTGKHEHSLLVEAYNSILFENGIPLMPLLSCGIFGVRIENSLKALFSC---- 1394
Query 1173 VYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKI 1232
+K + F+ +E+Q K + ++ P I + R + +
Sbjct 1395 ---------DINKPLQVFVYSSNEEQAVLKF--LDGLDLTPVIDDVDVVKPFRVEGNFSF 1443
Query 1233 KACVEEVTTTLEETKFLTENLLLYIDINGNLHPDS-ATLVSDIDITFLKKDAPYIVGDVV 1291
C + L N +L +D G L ++ + +L G++V
Sbjct 1444 FDCGVNALDG--DIYLLFTNSILMLDKQGQLLDTKLNGILQQAALDYLATVKTVPAGNLV 1501
Query 1292 QEGVLTAVV 1300
+ V + +
Sbjct 1502 KLFVESCTI 1510
Score = 69.7 bits (169), Expect = 1e-09, Method: Composition-based stats.
Identities = 43/192 (22%), Positives = 77/192 (40%), Gaps = 15/192 (8%)
Query 1648 SALNHTKKWKYPQVN--GLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAG 1705
L+ + + + + G+ + +DNNC+++T L+ LQ +L + +Q + G
Sbjct 1034 HVLSIKQPFSFSFRDELGVRVLDQSDNNCWISTTLVQLQLTKLLDDSIEMQL----FKVG 1089
Query 1706 EAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGV 1765
+ + + G LGD + +S L + +C + C CG++ G
Sbjct 1090 KVDSIVQKCYELSHLISGSLGDSGKLLSELLK--EKYTCSITFEMSCD-CGKKFDDQVG- 1145
Query 1766 EAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAP-PAQYELKHGTFTCA 1824
++ + F+KG C C K T LV + V + P P + C+
Sbjct 1146 --CLFWIMPYTKLFQKG--ECCICHKMQTYKLVSMKGTGVFVQDPAPIDIDAFPVKPICS 1201
Query 1825 SEYTGNYQCGHY 1836
S Y G GHY
Sbjct 1202 SVYLGVKGSGHY 1213
Score = 65.5 bits (158), Expect = 2e-08, Method: Composition-based stats.
Identities = 71/544 (13%), Positives = 146/544 (27%), Gaps = 82/544 (15%)
Query 153 PYEDFQENWNTKHSSGVTRELMREL-----NGGAYTRYVDNNFCGPDGYPLECIKDLLAR 207
P+ D N + ++++ +G +VD CG DG P+
Sbjct 77 PFSDRPLNLRGWLIFSNSNYVLQDFDVVFGHGAGSVVFVDKYMCGFDGKPVLP------- 129
Query 208 AGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFN 267
+ E D+ + +++AW R + SYE Q I+ T
Sbjct 130 -----KNMWEFRDYFNNNTDSIVIGGVTYQLAWDVIRKDLSYEQQNVLAIESIHYLGTT- 183
Query 268 GECPNFVFPLNSIIKTIQP---RVEKKKLDGFMGRIRSVYPVASPNE-------CNQMCL 317
+ +P + + R+ N +
Sbjct 184 ----GHTLKSGCKLTNAKPPKYSSKVVLSGEWNAVYRAFGSPFITNGMSLLDIIVKPVFF 239
Query 318 STLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNSE 377
+ +KC+ CG SW G C K +P + ++ C
Sbjct 240 NAFVKCN-CGSESWSVG-AWDGYLSSCCGTPAKKLCVVPGNVVPGDVIITSTSAGCG--- 294
Query 378 VGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTG 437
+ G V ++ + W + H+
Sbjct 295 -------------------------VKYYAGLVVKHITNITGVSLW------RVTAVHSD 323
Query 438 VVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLD-- 495
+ S D LL + + V N+ L + F + +D
Sbjct 324 GMFVAS-SSYDALLHRNSLDPFCFD-VNTLLSNQLRLAFLGASVTEDVKFAASTGVIDIS 381
Query 496 ---YKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSIFSRTL 552
+ + I+ + + V K A + + + R V+SI S L
Sbjct 382 AGMFGLYDDILTNNKPWFVRKASGLFDAI-WDAFVAAIKLVPTTTGVLVRFVKSIASTVL 440
Query 553 ETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLV------VMAYITGGVV 606
+ + + ++ + A F+ D+ V +V
Sbjct 441 TVSNGVIIMCADVPDAFQSVYRTFTQAICAAFDFSLDVFKIGDVKFKRLGDYVLTENALV 500
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+LT++ + + +K + + + ++ + G+IV
Sbjct 501 RLTTEVVRGVRDARIKKAMFTKVVVGPTTEVKFSVIELATVNLRLVDCAPVVCPKGKIVV 560
Query 667 CAKE 670
A +
Sbjct 561 IAGQ 564
Score = 38.1 bits (87), Expect = 4.6, Method: Composition-based stats.
Identities = 60/340 (18%), Positives = 112/340 (33%), Gaps = 36/340 (11%)
Query 637 EGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIG 696
E F+ D + +K T G + CAK + + + N FL
Sbjct 732 EKFNFVTDWLKTLKLTLTS-----NGLLGNCAKRFRRVLVKLLDVYNGFLETVCSVAYTA 786
Query 697 GAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEV 756
G +K + +V S + R V RE + P + + +T +
Sbjct 787 GVCIKYYAVNVPYVVISGFVSR--VIRRERCDMTFPCVSCVTFFYEFLDTCFGVSKPNAI 844
Query 757 VLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLK 816
++ +L ++ P G ++G L + D Y A V FT
Sbjct 845 DVEHLEL---KETVFVE---PKDGGQFFVSGDYLWYVVDDIYYPASCNG--VLPVAFTKL 896
Query 817 GGAPTKVTFGDDT-VIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVV 875
G K++F DD V +V+ V + FE ++ + L +K ++ + V+
Sbjct 897 AGG--KISFSDDVIVHDVEPTHKVKLIFEFEDDVVTSLCKKSFGKSIIYTGDWEGLHEVL 954
Query 876 ADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGD 935
A + + + +Y++DE G + ++ + S +P D
Sbjct 955 TSA--------------MNVIGQHIKLPQFYIYDEEGGYDVSKPVMISQWPISNDSNGCV 1000
Query 936 CEEEEF----EPSTQYEYGTEDDYQGKPLEFGATSAALQP 971
E E E D +P E +++
Sbjct 1001 VEASTDFHQLECIVDDSVREEVDIIEQPFEEVEHVLSIKQ 1040
>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709
Score = 6723 bits (17443), Expect = 0.0, Method: Composition-based stats.
Identities = 2227/4982 (45%), Positives = 3058/4982 (61%), Gaps = 182/4982 (4%)
Query 2163 RVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPN 2222
++ + F LL+ +S ++K P + +N V NY++ N
Sbjct 1859 KILRFLLEVFKYLLVVFMCLRKSKMPKVKVK-PPHVFRNLGAKVRTL------NYVRQLN 1911
Query 2223 FSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYC 2282
L I LLL + L Y ++ V+ C+G + Y NS+ + C
Sbjct 1912 KPALWRYIKLVLLL-IALYHFFYLFVSIPVVHK-----LACSGSVQAYSNSS-FVKSEVC 1964
Query 2283 TGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWD----LTAFGLVAEWFLAYILFTRFF 2338
SI C CL+ D L + L+ S W+ L+ F +A + Y+ R
Sbjct 1965 GNSILCKACLASYDELADFDHLQVSWDYKSDPLWNRVIQLSYFIFLAVFGNNYV---RCL 2021
Query 2339 YVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYV 2398
+ ++ + L+ SYF ++ SW + ++V IS + + K
Sbjct 2022 LMYFVSQYLNLWLSYFG--YVKYSWFL----HVVNFESISVEFVIIVVVFKAVLALK--- 2072
Query 2399 HVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTF 2458
H+ CN+ +C C K R TR+ +VNG ++ YV+ANG CK HN+ C NCD++
Sbjct 2073 HIFLPCNNPSCKTCSKIARQTRIPIQVVVNGSMKTVYVHANGTGKLCKKHNFYCKNCDSY 2132
Query 2459 CAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLY---------FDKAG 2509
TFI DE+ RDLS K+ + TD+S V V +G Y +D
Sbjct 2133 GFDHTFICDEIVRDLSNSIKQTVYATDRSYQEVTKVECTDGFYRFYVGEEFTAYDYDVKH 2192
Query 2510 QKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPI 2569
+K + L LD+ N GS +S ++ VY+SQL+ +PI
Sbjct 2193 KKYSSQEVLKTMFLLDDFIVYNPSGS--------------SLASVRNVCVYFSQLIGRPI 2238
Query 2570 LLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNV 2629
+++ L+ D+ S + +F+A N ++FNV + + K L E K +LD
Sbjct 2239 KIVNSELLEDL--SVDFKGALFNAKKNVIKNSFNVDVSECKNL-----EECYKLCNLDVT 2291
Query 2630 LSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKV--ENMTPRD 2687
STF A +H+ I +T S NN+ + K ++ D
Sbjct 2292 FSTFEMAINN------------------AHRFGILITDRSFNNFWPSKIKPGSSGVSAMD 2333
Query 2688 LGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATT 2747
+G C+ A+ +NA+V +++W +DF +LS +K + + + F LT
Sbjct 2334 IGKCMTFDAKIVNAKVLTQRGKSVVWLSQDFSTLSSTAQKVLVKTFVEEGVNFSLTFNAV 2393
Query 2748 RQVVNVV----TTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFS 2803
++ T ++ K G + LKQL ++ + ++ L + V ++ S
Sbjct 2394 GSDEDLPYERFTESVSAKSGSGFFDVLKQLKQLFWCLVLFITLYGLCSVYSVATQSYIDS 2453
Query 2804 SEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGS-YTNDKACPLIAA-VITRE 2861
+E Y I GV + + C N + F WF + G T DK+CP++ V
Sbjct 2454 AEGYDYMVIKNGVVQSFDDSINCVHNTYKGFAVWFKAKHGFVPTFDKSCPIVLGTVFDLG 2513
Query 2862 VGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTI 2921
+P +P + G L F V N+CY + + CV + CT
Sbjct 2514 NMRPIPDVPAYVALV--GRSLVFAINAAFGVTNVCYDHTGAAVSKNSYFDTCVFNSACTT 2571
Query 2922 FKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDS 2981
G V YC ++EG+ Y L PD Y G++++ P +R V T +
Sbjct 2572 LTGIGGTVV-YCAKQGLVEGAKLYSELLPDYYYEHASGNMVKIPAIIRSFGLRFVKTQAT 2630
Query 2982 EYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGAL 3041
YCR G C S+AG C +V + ++ G CG + N+F + +
Sbjct 2631 TYCRVGECTESQAGFCFGGDNWFVYDKEFG---DGYICGSSTLGFFKNVFALFNSNMSVV 2687
Query 3042 DISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFL 3101
S +++A ++A + + Y ++F++ FG+ + +V + +++ +T
Sbjct 2688 ATSGAMLANIVIACLAIAVCYGVLKFKKIFGDCTLLVVMIIVTLVVNNVSYFVTQ----- 2742
Query 3102 PGVYSVIYLYLTFYLTNDVSF--LAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSN 3159
+ ++Y + ++ T +++ + +++ + + P+++ + YI+ Y +
Sbjct 2743 NTFFMIVYAIIYYFTTRKLAYPGVLDAGFIIAYLNMAPWYVLVLYIMVF----LYDSLPS 2798
Query 3160 YLKRRV---VFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYK 3215
K +V +F G F +FE AA+ TF+++ Y L + L + Y +NKYK
Sbjct 2799 LFKLKVTTNLFEGDKFVGSFESAAMGTFVIDMRSYETLVNST--SLDRIKSYANSFNKYK 2856
Query 3216 YFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGK 3275
Y++G+M YR A HL KAL D+S S +D+LY PP S+ S LQSG RKMA PSG
Sbjct 2857 YYTGSMGEADYRMACYAHLGKALMDYSVSRNDMLYTPPTVSVNST-LQSGLRKMAQPSGV 2915
Query 3276 VEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGN 3335
VE C+V+V G LNGLWL D V CPRHVI + + NYE+ L HNF + N
Sbjct 2916 VEPCIVRVAYGNNVLNGLWLGDEVICPRHVIASDTSRV-INYENELSSVRLHNFSIAKNN 2974
Query 3336 VQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRP 3395
L V+ + L LKV+ NP TP++KF ++PG++F++LACY G P VY MR
Sbjct 2975 AFLGVVSAKYKGVNLVLKVNQVNPNTPEHKFKSVRPGESFNILACYEGCPGSVYGVNMRS 3034
Query 3396 NFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQ 3455
TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++LEG YG + D+ + Q
Sbjct 3035 QGTIKGSFIAGTCGSVGYVLENGTLYFVYMHHLELGNGSHVGSNLEGEMYGGYEDQPSMQ 3094
Query 3456 AAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGP 3515
GT+ + NV+A+LYAA+ING+RWF+ + TL +N A ++ + D
Sbjct 3095 LEGTNVMSSDNVVAFLYAALINGERWFVTNTSMTLESYNAWAKTNSFTEIVS--TDAFNM 3152
Query 3516 LSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRT 3575
L+A+TG +V + + L G GRTIL L DEFTP +V+RQ GV QS ++
Sbjct 3153 LAAKTGYSVEKLLECIVRL-NKGFGGRTILSYGSLCDEFTPTEVIRQMYGVNLQSGKVKS 3211
Query 3576 IKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAF 3635
I + + L T ++ ++ +S + +KHK F
Sbjct 3212 IFYPMMTAIAILFAFWLEFFMYTPFT---WINPTFVSVVLAITTLVSVLLVAGIKHKMLF 3268
Query 3636 LCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILM 3695
F++PS+ N V ++ + ++ V+T+ ++ ++ VV+ ++
Sbjct 3269 FMSFVMPSVILATAHN-VVWDMTYYESLQVLVENVNTTFLPVDMQGVMLALFCVVVFVIC 3327
Query 3696 TARTVYDDGARR------VWTLMNVLTLVYKVYYGNALD----QAISMWALIISVTSNYS 3745
T R + ++ + N++ L+ + D ++M ++IS+T+
Sbjct 3328 TIRFFTCKQSWFSLFATTIFVMFNIVKLLGMIGEPWTDDHFLLCLVNMLTMLISLTTKDW 3387
Query 3746 GVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFR 3805
VV +A IV ++ P F ++C+ ++Y GY CY+G+ +NR+
Sbjct 3388 FVVFASYKVAYYIVVYVMQ--PAFVQDFGFVKCVSIIYMACGYLFCCYYGILYWVNRFTC 3445
Query 3806 LTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDV 3865
+T GVY + VS E +YM + L PK + DA L+ KL+G+GG IK++TVQSK++++
Sbjct 3446 MTCGVYQFTVSPAELKYMTANNLSAPKTAYDAMILSFKLMGIGGGRNIKISTVQSKLTEM 3505
Query 3866 KCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAV 3925
KCT+VVLL +L ++ VES+SK W CV LHN+I L D EK+++L++ LS
Sbjct 3506 KCTNVVLLGLLSKMHVESNSKEWNYCVGLHNEINLCDDPDAVLEKLLALIAFFLSKHNTC 3565
Query 3926 DINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLN 3985
D++ L E +N LQ++AS +++LPS+ A+ A+ E+A N S +LK+L K+ N
Sbjct 3566 DLSDLIESYFENTTILQSVASAYAALPSWIAYEKARADLEEAKKNDVSPQLLKQLTKACN 3625
Query 3986 VAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDAL 4045
+AKSEF+R+A++Q+KL+KMA+QA MYK+AR+ D+++K+ SAM ++LF ML+KLD ++
Sbjct 3626 IAKSEFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSV 3685
Query 4046 NNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDAD 4105
N II AR+G +PL+IIP +A +L+VV P+ YA A+W I +V DA+
Sbjct 3686 NTIIEQARNGVLPLSIIPAASATRLIVVTPNLEVLSKVRQENNVHYAGAIWSIVEVKDAN 3745
Query 4106 SKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTD 4165
V L E++ N N+ WPL +T R KLQNNE+ P L++ + A T
Sbjct 3746 GAQVHLKEVTAANELNITWPLSITCERTT---KLQNNEILPGKLKEKAVKASATIDGDAY 3802
Query 4166 DNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKV 4225
+ A + G F+ A ++ +LK+ ++ + I ELE P RF D GP+V
Sbjct 3803 GSGKALMASEGGKSFIYAFIASDSNLKYVKWESN--NDVIPIELEAPLRFYVDGVNGPEV 3860
Query 4226 KYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLA 4285
KYLYF+K LN L RG VLG + ATVRLQAG TE P+NS +L+ CAFA D AKAY D +
Sbjct 3861 KYLYFVKSLNTLRRGAVLGYIGATVRLQAGKPTEHPSNSGLLTLCAFAPDPAKAYVDAVK 3920
Query 4286 SGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDL 4345
G QP+TNCVKML G G AIT E+N Q+S+GGAS C+YCRCH++HP G C
Sbjct 3921 RGMQPVTNCVKMLSNGAGNGMAITNGVESNTQQDSYGGASVCIYCRCHVEHPAIDGLCRF 3980
Query 4346 KGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCG 4405
KGK+VQ+PT DP+ F ++N VC VCG W GC CD R + + QS+LN
Sbjct 3981 KGKFVQVPTG-TQDPIRFCIENEVCVVCGCWLTNGCMCD--RTSIQGTTIDQSYLNECGV 4037
Query 4406 VSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVK 4465
+ L PC GT D V RAFDIYN VA KFLKTNC RF+ D+ D+Y+VVK
Sbjct 4038 LVQLDLEPC-NGTDPDHVSRAFDIYNKDVACIGKFLKTNCSRFRNLDKH----DAYYVVK 4092
Query 4466 RHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRH 4525
R T S HE+ YN LKD VA+HDFF ++ +++R+ LTKYTM DL YA+R+
Sbjct 4093 RCTKSVMDHEQVCYNDLKDSGVVAEHDFFLYKEGRCEFGNVARKDLTKYTMMDLCYAIRN 4152
Query 4526 FDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFC 4585
FDE NC+ LKEILVT C++ +F KDW+D VEN I VYA LG V A+LK V FC
Sbjct 4153 FDEKNCEVLKEILVTLGACNESFFENKDWFDPVENEAIHEVYARLGPIVANAMLKCVAFC 4212
Query 4586 DAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTA 4645
DA+ G +G++TLDNQDLNGN+YDFGDF++TTPG G V SYYS +MP++ +T L +
Sbjct 4213 DAIVEKGYIGIITLDNQDLNGNFYDFGDFVKTTPGFGCACVTSYYSYMMPLMGMTSCLES 4272
Query 4646 ESHVDTDL-TKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCAN 4704
E+ V +D+ Y ++DLL YDFT+ + KLF +YFK+WD+TYHPNC +C D CI+HCAN
Sbjct 4273 ENFVKSDIYGADYKQYDLLAYDFTDHKEKLFHKYFKHWDRTYHPNCSDCTSDECIIHCAN 4332
Query 4705 FNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELL 4764
FN LFS P T+FGPLVRK+ +DGVP VV+ GYHF++LG+V N DV L + +LS +LL
Sbjct 4333 FNTLFSMTIPSTAFGPLVRKVHIDGVPVVVTAGYHFKQLGIVWNLDVKLDTMKLSMTDLL 4392
Query 4765 VYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEG 4824
+ DP + AS LLD+RT CFS+AAL+ V +QTVKPG+FNKDFYDF +GFF+EG
Sbjct 4393 RFVTDPTLLVASSPALLDQRTVCFSIAALSTGVTYQTVKPGHFNKDFYDFITERGFFEEG 4452
Query 4825 SSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQ 4884
S + LKHFFFAQ G AA++D++YYRYN T+ DI Q FV ++V KYF+CYDGGCINA +
Sbjct 4453 SELTLKHFFFAQGGEAAMTDFNYYRYNRVTVLDICQAQFVYKIVGKYFECYDGGCINARE 4512
Query 4885 VIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKN 4944
V+V N DKSAG+P NK+GKARLYY+++SYE+QDALFA TKRNV+PT+TQMNLKYAIS K
Sbjct 4513 VVVTNYDKSAGYPLNKFGKARLYYETLSYEEQDALFALTKRNVLPTMTQMNLKYAISGKA 4572
Query 4945 RARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENP 5004
RARTV GVS+ STMT RQ+HQK LKSIAATR ATVVIG++KFYGGW NMLK + DV+N
Sbjct 4573 RARTVGGVSLLSTMTTRQYHQKHLKSIAATRNATVVIGSTKFYGGWDNMLKNLMRDVDNG 4632
Query 5005 HLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGS 5064
LMGWDYPKCDRA+PNM+R+ ++++L KH CC+ S RFYRL+NE AQVL+E+V C G
Sbjct 4633 CLMGWDYPKCDRALPNMIRMASAMILGSKHVGCCTHSDRFYRLSNELAQVLTEVVHCTGG 4692
Query 5065 LYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLY 5124
Y KPGGT+SGD TTAYANS FNI QAV+ANVN LL D N + V+++Q ++Y+ Y
Sbjct 4693 FYFKPGGTTSGDGTTAYANSAFNIFQAVSANVNKLLGVDSNACNNVTVKSIQRKIYDNCY 4752
Query 5125 RNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNV 5184
R+ +D +FV E+++YLRKHFSMMILSDD VVC+N YA G VA I FK+ LYYQNNV
Sbjct 4753 RSSSIDEEFVVEYFSYLRKHFSMMILSDDGVVCYNKDYADLGYVADINAFKATLYYQNNV 4812
Query 5185 FMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDG 5244
FMS +KCW E DL+ GPHEFCSQHT+ + D YLPYPDPSRIL AG FVDDIVKTD
Sbjct 4813 FMSTSKCWVEPDLSVGPHEFCSQHTLQIVGPDGDYYLPYPDPSRILSAGVFVDDIVKTDN 4872
Query 5245 TLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNT 5304
+M+ER+VSLAIDAYPLTKHP Y VF+ L +++ L L +LD +SV + +
Sbjct 4873 VIMLERYVSLAIDAYPLTKHPKPAYQKVFYTLLDWVKHLQKNLNAGVLDSFSVTMLEEGQ 4932
Query 5305 SRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHK 5364
++W EFY ++Y TVLQA G CV+C SQT LRCG C+RRP LC KC YDHV+ T HK
Sbjct 4933 DKFWSEEFYASLYEKSTVLQAAGMCVVCGSQTVLRCGDCLRRPLLCTKCAYDHVMGTKHK 4992
Query 5365 LVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGS 5424
++S+ PYVC+ GC+V DVT+L+LGG+SYYC HKP +SFPLCANG VFGLYK++ VGS
Sbjct 4993 FIMSITPYVCSFNGCNVNDVTKLFLGGLSYYCMDHKPQLSFPLCANGNVFGLYKSSAVGS 5052
Query 5425 DNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSD 5484
++V DFN +A DWTN DY LAN E LK+FAAET+KA EE+ K Y A ++EV+
Sbjct 5053 EDVEDFNKLAVSDWTNVEDYKLANNVKESLKIFAAETVKAKEESVKSEYAYAILKEVIGP 5112
Query 5485 RELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYG-DAVVYRGTTTYKL 5543
+E+ L WE K +PPLNRN VFT ++++K++K+Q+GE+ FE+ +YG D+V Y+ T+TYKL
Sbjct 5113 KEIVLQWEASKTKPPLNRNSVFTCFQISKDTKIQLGEFVFEQSEYGSDSVYYKSTSTYKL 5172
Query 5544 NVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYST 5603
G FVLTSH V PL A LV QE Y I+ LYP NI++ +++ V YQ +G QK++T
Sbjct 5173 TPGMIFVLTSHNVSPLKATILVNQEKYNTISKLYPVFNIAEAYNTLVPYYQMIGKQKFTT 5232
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+QGPPG+GKSH IGL LYYP ARIVYTACSHAAVDALCEKA K +D+CSRIIP R R
Sbjct 5233 IQGPPGSGKSHCVIGLGLYYPQARIVYTACSHAAVDALCEKAAKNFNVDRCSRIIPQRIR 5292
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5723
V+C+ FK N+T QY+FCTVNALPE + DIVV DE+SM TNYDLSV+N+RL KH VY+
Sbjct 5293 VDCYTGFKPNNTNAQYLFCTVNALPEASCDIVVVDEVSMCTNYDLSVINSRLSYKHIVYV 5352
Query 5724 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5783
GDP QLPAPRTL+ KG L+P+ +N V + + T+GPD+FL C RCPAEIV TVSALVY+N
Sbjct 5353 GDPQQLPAPRTLINKGVLQPQDYNVVTQRVCTLGPDVFLHKCYRCPAEIVKTVSALVYEN 5412
Query 5784 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5843
K +S QCFKMF KG + + +S+IN Q+ VV+ FL NP WRKAVFISPYNSQN
Sbjct 5413 KFVPVNPESKQCFKMFVKGQVQIESNSSINNKQLEVVKAFLAHNPKWRKAVFISPYNSQN 5472
Query 5844 AVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDR 5903
VA ++LGL TQTVDS+QGSEYDYVI+TQT++T H+ NVNRFNVAITRAKVGILCIM DR
Sbjct 5473 YVARRLLGLQTQTVDSAQGSEYDYVIYTQTSDTQHATNVNRFNVAITRAKVGILCIMCDR 5532
Query 5904 DLYDKLQFTSLEIPRRNVATLQAEN-VTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-E 5961
+Y+ L F L+ + LQA+ GLFKDCSK + P A T++S+ FKT +
Sbjct 5533 TMYENLDFYELKDSKI---GLQAKPETCGLFKDCSKSEQYIPPAYATTYMSLSDNFKTSD 5589
Query 5962 GLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHA 6021
GL V+I KD+ Y +IS MGF+ + GY +F TR+ A+R+VRAW+GFDVEG H
Sbjct 5590 GLAVNIG--TKDVKYANVISYMGFRFEANIPGYHTLFCTRDFAMRNVRAWLGFDVEGAHV 5647
Query 6022 TREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKG 6081
+ VGTN+PLQLGFS GV+ V G V T V A+ PPG+QF HLIPLM KG
Sbjct 5648 CGDNVGTNVPLQLGFSNGVDFVVQTEGCVVTEKGNSIEVVKARAPPGEQFAHLIPLMRKG 5707
Query 6082 LPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATC 6141
PW++VR +IVQM+ D LSD ++FVLWA G ELT+M+YFVKIG + C C + ATC
Sbjct 5708 QPWHIVRRRIVQMVCDYFDGLSDILIFVLWAGGLELTTMRYFVKIGRPQKCE-CGKSATC 5766
Query 6142 FSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIM 6201
+S++ YAC+ H++G DY+YNP+ ID+QQWG+TG+L NH C +H N HVAS DAIM
Sbjct 5767 YSSSQCVYACFKHALGCDYLYNPYCIDIQQWGYTGSLSMNHHEVCNIHRNEHVASGDAIM 5826
Query 6202 TRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPK 6261
TRCLA+H+CFVKRVDW+I YP I +E KIN A R VQ V+KAAL +HD+GNPK
Sbjct 5827 TRCLAIHDCFVKRVDWSIVYPFIDNEEKINKAGRIVQSHVMKAALKIFNPAAIHDVGNPK 5886
Query 6262 AIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANS 6321
I+C + W YD P ++ +E Y Y H +G+ LFWNCNVD YP S
Sbjct 5887 GIRCA-TTPIPWFCYDRDPINNNVRCLE---YDYMVHGQ--MNGLMLFWNCNVDMYPEFS 5940
Query 6322 IVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHG 6381
IVCRFDTR S L+L GC+GG+LYVN HAFHTPA+D+ AF LK +PFFYY DS CE
Sbjct 5941 IVCRFDTRTRSKLSLEGCNGGALYVNNHAFHTPAYDRRAFAKLKPMPFFYYDDSNCE--- 5997
Query 6382 KQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDT 6441
V +YVPLKS CIT+CN+GGAVC+ HA YR Y++ YNM + AGF++W + FDT
Sbjct 5998 -LVDGQPNYVPLKSNVCITKCNIGGAVCKKHAALYRAYVEDYNMFMQAGFTIWCPQNFDT 6056
Query 6442 YNLWNTFTR---LQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENK 6498
Y LW+ F LQSLENVAFNVV KG F G +G++P ++I + + + D +F NK
Sbjct 6057 YMLWHGFVNSKALQSLENVAFNVVKKGAFTGLKGDLPTAVIADKIMVRDGPTDKCIFTNK 6116
Query 6499 TTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTD 6558
T+LP NVAFEL+AKR + P + IL NLGV V+WDY+ + P T VCS TD
Sbjct 6117 TSLPTNVAFELYAKRKLGLTPPLTILRNLGVVATYKFVLWDYEAECPFSNFTKQVCSYTD 6176
Query 6559 IAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVT 6618
+ + + FD + G + F ++ VLI+ +VKGL ++ + LN +
Sbjct 6177 LDSE--------VVTCFDNSIAGSFERFTTTKDAVLISNNAVKGLS-AIKLQYGFLNDLP 6227
Query 6619 L--IGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIER 6676
+ +G T + Y +K V+Q+ ++Y+T R + FKPRS ME DFL + FI++
Sbjct 6228 VSTVGNKPVTWYIYVRKNGEYVEQI-DSYYTHGRTFETFKPRSTMEEDFLSMDTTLFIQK 6286
Query 6677 YKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFI-PMDSTVKNYFITDA 6735
Y LE Y FEH+V+GD S + +GG+HLLI + K F +++F+ DST+K+ IT A
Sbjct 6287 YGLEDYGFEHVVFGDVSKTTIGGMHLLISQVRLAKMGLFSVQEFMTNSDSTLKSCCITYA 6346
Query 6736 QTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYP 6795
SSK VC+ +D+LLDDFV IIKS DL+VVSKVV V +D +MLWC++ ++TFYP
Sbjct 6347 DDPSSKNVCTYMDILLDDFVTIIKSLDLNVVSKVVDVIVDCKAWRWMLWCENSQIKTFYP 6406
Query 6796 KLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTL 6855
+LQS++ W PG +MP LYK+QRM LE+C+L NYG LP GI NV KYTQLCQYLNT
Sbjct 6407 QLQSAE-WNPGYSMPTLYKIQRMCLERCNLYNYGAQVRLPDGITTNVVKYTQLCQYLNTT 6465
Query 6856 TLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCAT 6915
T+ VP+ MRV+H GA GVAPG+ VLR+WLP +LVD+DL D+VSDAD ++ GDC +
Sbjct 6466 TVCVPHKMRVLHLGAAGASGVAPGSTVLRRWLPDDAILVDNDLRDYVSDADFSVTGDCTS 6525
Query 6916 VHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWN 6975
++ +K+DL+ISD+YD TK++ EN SK+GFFTYI GFI++KL+LGGS AIKITE SWN
Sbjct 6526 LYIEDKFDLLISDLYDGSTKSIDGENTSKDGFFTYINGFIKEKLSLGGSAAIKITEFSWN 6585
Query 6976 ADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGK--PREQIDGYVMHANYIFWRNTN 7033
DLY+L+ F +WT F T+VN SSSE FLIG NYLG + +DG +MHANYIFWRN+
Sbjct 6586 KDLYELIQRFEYWTVFCTSVNTSSSEGFLIGINYLGPYCDKAIVDGNIMHANYIFWRNST 6645
Query 7034 PIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVL 7093
+ LS S+ D KF + +++LKE ++N+M++ LL KG+L+IR N +++ + L
Sbjct 6646 IMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVVGLLRKGKLLIRNNGKLLNFGNHL 6705
Query 7094 VN 7095
VN
Sbjct 6706 VN 6707
Score = 191 bits (484), Expect = 4e-46, Method: Composition-based stats.
Identities = 62/290 (21%), Positives = 119/290 (41%), Gaps = 25/290 (9%)
Query 999 TTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVV 1058
T +T+VE +E + Q+ + Y V D+ ++P V+V
Sbjct 1305 TAKSKTMVEPPVPVEDKCVEDCQSPKDLILPFYK--AGKVSFYQGDLDVLINFLEPDVLV 1362
Query 1059 NAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVV 1118
NAAN L+H GGVA A++ T + S +Y+ ++ + G + + L+ V
Sbjct 1363 NAANGDLRHVGGVARAIDVFTGGKLTKRSKEYLKSSKAIAPGNAVLFENVLEHLSVLNAV 1422
Query 1119 GPNVNKGEDIQLLKSAYENFNQHE-VLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAV 1177
GP L + Y+ + + +L PL+S GIF V+ V L
Sbjct 1423 GPRNGDSRVEGKLCNVYKAIAKCDGKILTPLISVGIF-------------KVKLEVSLQC 1469
Query 1178 FDKNLYDKLVSSFLEMKSEKQVEQKI--AEIPKEEVKPFITESKPSVEQRKQDDKKIKAC 1235
K + D+ ++ F+ E+ + IP + + + + + SV K +++K
Sbjct 1470 LLKTVTDRDLNVFVYTDQERVTIENFFNGTIPIKVTEDTVNQKRVSVALDKTYGEQLKGT 1529
Query 1236 V----EEVTTTLEETKFLTENLLLYIDINGNLH---PDSATLVSDIDITF 1278
V ++VT L + E ++ +D++ N + P++A + +
Sbjct 1530 VVIKDKDVTNQLPSVSDVGEKVVKALDVDWNAYYGFPNAAAFSASSHDAY 1579
Score = 147 bits (372), Expect = 4e-33, Method: Composition-based stats.
Identities = 67/345 (19%), Positives = 113/345 (33%), Gaps = 34/345 (10%)
Query 1554 DNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQF-GPTYLDGADVTKIKPHNS 1612
D + + TI + T D +N V + TYG+Q G + DVT P S
Sbjct 1486 DQERVTIENFFNGTIPIKVTEDTVNQKRVSVALDKTYGEQLKGTVVIKDKDVTNQLPSVS 1545
Query 1613 HEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADN 1672
G+ L V+ YY + + ++ + ++ N K DN
Sbjct 1546 DVGEKV-----VKALDVDWNAYYGFPNA---AAFSASSHDAYEFDVVTHNNFIVHKQTDN 1597
Query 1673 NCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETM 1732
NC++ L LQ+++ + P ++ + + A F ++ T G+ GD T+
Sbjct 1598 NCWVNAICLALQRLKPTWKFPGVKSLWDAFLTRKTAGFVHMLYHISGLTKGQPGDAELTL 1657
Query 1733 SYLFQHANLDSCKRV-LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGK 1791
L + DS V C C + T G + G C G
Sbjct 1658 HKLVDLMSSDSAVTVTHTTACDKC-AKVETFTGPVVAAPL-------LVCGTDEICVHGV 1709
Query 1792 QATKYLVQQESPFVMMS-APPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDG 1850
+ + S P ++ T YTG GHY + ++ L +D
Sbjct 1710 HVNVKVTSIRGTVAITSLIGPVVGDVIDATGY--ICYTGLNSRGHYTYYDNRNGL-MVDA 1766
Query 1851 ALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPK 1895
+++N T + + EI PK
Sbjct 1767 DKAYH------------FEKNLLQVTTAIASNFVANTPKKEIMPK 1799
Score = 141 bits (356), Expect = 3e-31, Method: Composition-based stats.
Identities = 67/367 (18%), Positives = 120/367 (33%), Gaps = 48/367 (13%)
Query 1574 VDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFE 1633
V ++ T V + +Q + + P L + + + +
Sbjct 1025 VSSVEGETVSVVDVEDFVEQVSLVEENNVLTPAVNPDE--------QLSSVEKKDEVSAK 1076
Query 1634 YYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPP 1693
+K +NG +K DNNC++ LQ + FN
Sbjct 1077 NDPWAAAVDEQEAEQPKPSLTPFKTTNLNGKIILKQQDNNCWINACCYQLQAFDF-FN-- 1133
Query 1694 ALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCK 1753
D + + + F A G+ GD + + + + K L+ C
Sbjct 1134 --HDLWDGFKKDDVMPFVDFCYAALTLKQGDSGDAEYLLETMLN--DYSTAKVTLSAKCG 1189
Query 1754 TCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPC----TCGKQATKYL-------VQQES 1802
CG ++ L E ++ T +FK GV C C + + +++++
Sbjct 1190 -CGVKEIVL---ERTVFKLTPLRNEFKYGVCGDCKQINMCKFASVEGSGVFVHDRIEKQT 1245
Query 1803 PFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGP 1862
P P + + YTG Q GHY YC+DG + K ++K
Sbjct 1246 PVSQFIVTPTMHAV----------YTGTTQSGHYMIEDCI-HDYCVDG-MGIKPRKHKFY 1293
Query 1863 ITDVFYKENSYTTTIK-----PVTYKLDGVVCTEIDPKLD-NYYKKDNSYFTEQPIDLVP 1916
+ +F N T K PV + V + L +YK F + +D++
Sbjct 1294 TSTLFLNANVMTAKSKTMVEPPVPVEDKCVEDCQSPKDLILPFYKAGKVSFYQGDLDVLI 1353
Query 1917 NQPYPNA 1923
N P+
Sbjct 1354 NFLEPDV 1360
Score = 77.4 bits (189), Expect = 6e-12, Method: Composition-based stats.
Identities = 54/308 (18%), Positives = 105/308 (34%), Gaps = 17/308 (6%)
Query 745 ETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAP 804
+T V ++ P+ ++ VE G + I G + +D Y
Sbjct 808 KTASVPVTNSGIITTDDWSDPILLEPADYVEPKDNGDVIVIAGYTFYKDEDDHFYP--YG 865
Query 805 NMMVTNNTFTLKGGAPTKVTFGDD-TVIEVQGYKSVNITFELD-ERIDKVLNEKCSAYTV 862
+ MV + GG V+F D+ V E++ V + FE D E + +VL +
Sbjct 866 SGMVVQKMYNKMGGGDKSVSFSDNVNVREIEPVTRVRLEFEFDNEVVTQVLEKVIGTKYK 925
Query 863 ELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE-WSMATYYLFDESGEFKLASHMY 921
+GT EF D++ + L + + L G++L+ + T FD + + Y
Sbjct 926 FIGTTWEEF----EDSISEKLDKIFDTLAEQGVELEGYFIYDTCGGFDINNPDGVMISQY 981
Query 922 CSFYPPDEDEEEGDCEEE-------EFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEE 974
D+ + E+ E + + + DD + G T + + E+
Sbjct 982 DLNTAADDKSDSDASVEDISLISDNEDVEQIEEDNTSTDDAEDVSSVEGETVSVVDVEDF 1041
Query 975 QEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVE-VQPQLEMELTPVVQTIEVNSFSGYLK 1033
E+ L +++ + E + + V + S + +
Sbjct 1042 VEQVSLVEENNVLTPAVNPDEQLSSVEKKDEVSAKNDPWAAAVDEQEAEQPKPSLTPFKT 1101
Query 1034 LTDNVYIK 1041
N I
Sbjct 1102 TNLNGKII 1109
Score = 57.8 bits (138), Expect = 5e-06, Method: Composition-based stats.
Identities = 46/210 (22%), Positives = 66/210 (31%), Gaps = 35/210 (17%)
Query 174 MRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCRE 233
++ G YVD CG DG P+ + + V
Sbjct 102 LKFARTGNGAIYVDQYMCGADGKPV----------------IEGEFKDYFGDEDVIIYEG 145
Query 234 HEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKL 293
E+ AW T R EK QT I+ + N + P+ + N I+ + P V+K
Sbjct 146 EEYHCAWLTVRDEKPLWQQTLLTIREIQY----NLDIPHKL--PNCAIREVAPPVKKNSK 199
Query 294 DGFMGRIRSVYPVAS---------PNECNQMCLS--TLMKCDHCGETSWQTGDFVKATCE 342
R +Y + N C +KC CG S GD+
Sbjct 200 VVLSEEYRKLYDIFGSPFMGNGDSLNTCFDSLHFIAATLKC-PCGAESSGVGDWTGFKTA 258
Query 343 FCGTENLTKEGATTCGYLPQNAVVKIYCPA 372
CG K G T P +A+V
Sbjct 259 CCGLHGKVK-GVTLGAVKPGDAIVTSMSAG 287
>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1
SV=1
Length=6629
Score = 6690 bits (17356), Expect = 0.0, Method: Composition-based stats.
Identities = 2367/5696 (42%), Positives = 3295/5696 (58%), Gaps = 376/5696 (7%)
Query 1549 EVITFDNLKTLLSLREV--RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTK 1606
V+ F + + +V + ++ T D + + V+ + G QFG Y V
Sbjct 1157 RVLLFSLSQEHIDYFDVTCKQKTIYLTEDGVKYRSIVLKPGDSLG-QFGQVYAKNKIV-- 1213
Query 1607 IKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTS 1666
+ + + YV D ++ EYY D Y+ L +KW +
Sbjct 1214 FTADDVEDKEILYVPTTDKSI----LEYYG-LDAQKYVIYLQTL--AQKWNVQYRDNFLI 1266
Query 1667 IKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELG 1726
++W D NC++++A++ LQ +++F L +A+ + G+ +F A A C VG+
Sbjct 1267 LEWRDGNCWISSAIVLLQAAKIRFK-GFLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFS 1325
Query 1727 DVRETMSYLFQHANLDSCKRVLNV-VCKTCGQQQTTLKGVEAVM-YMGTLSYEQFKKGVQ 1784
D ++ L +H + D L V CG + L+G+EA + + + FK
Sbjct 1326 DANWLLANLAEHFDADYTNAFLKKRVSCNCGIKSYELRGLEACIQPVRATNLLHFKTQYS 1385
Query 1785 IPCTCGKQATKYLVQQESPFVMMSAP--PAQYELKHGTFTCASEYTGNYQCGH-YKHITS 1841
TCG T +++ P++++ A PA + + G+ GH Y
Sbjct 1386 NCPTCGANNTDEVIEASLPYLLLFATDGPATVDCDEDAVGT-VVFVGSTNSGHCYTQA-- 1442
Query 1842 KETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYK 1901
D + K P Y ++ K + + N
Sbjct 1443 --AGQAFDNLAKDRKFGKKSPYITAMYTRFAFKNETSLPVAKQSKGKSKSVKEDVSNL-- 1498
Query 1902 KDNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFP 1961
ASFDN D Q Y LKV P
Sbjct 1499 ----------------ATSSKASFDNL----------TDFEQW--YDSNIYESLKVQESP 1530
Query 1962 DLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVET 2021
D ++ Y T + + P T +R + S +
Sbjct 1531 D--------NFDKYVS------------------FTTKEDSKLPLTLKVRGIKSVVDFRS 1564
Query 2022 SNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVK---------TTEVV 2072
+ F + D PV V++ +++ +E N + +
Sbjct 1565 KDGFIYKLTPDTD------ENSKAPVYYPVLDAISLKAIWVEGNANFVVGHPNYYSKSLH 1618
Query 2073 GDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNS 2132
+ A N +K+ +++G + ++ + KPN L R+ + A G + V +
Sbjct 1619 IPTFWENAENFVKMGDKIGGVTMGLWRAEH----LNKPN-LERIFNIAKKAIVGSSVVTT 1673
Query 2133 VPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVC--------TNYMPYFF-TLLLQLCTFT 2183
I A +KV +T + +C P F TL+ L F
Sbjct 1674 QCGKLIGKAATFIADKVGGGVVRNITDSIKGLCGITRGHFERKMSPQFLKTLMFFLFYFL 1733
Query 2184 RSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSL 2243
+++ + AS T + K + ++ +I+WF+ S +
Sbjct 1734 KASVKSVVASYKTVLCKVVLATL----------------------LIVWFVYTS---NPV 1768
Query 2244 IYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPS 2303
+++ + + L S C Y++ +S + YC C VCL DSL Y
Sbjct 1769 MFTGIRV---LDFLFEGSLCGPYKDYGKDS--FDVLRYCADDFICRVCLHDKDSLHLYKH 1823
Query 2304 LETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAIMQLFFSYFAVHFISN 2361
+++ A G + W Y++F F V G I Y + + N
Sbjct 1824 AYSVEQVYKD-----AASGFIFNWNWLYLVFLILFVKPVAGFVII-----CYCVKYLVLN 1873
Query 2362 SWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVVDGCNSSTCMMCYKRN 2416
S ++ + + + + + F + +Y W Y VH + C TC +C +
Sbjct 1874 STVLQTGVCFLDWF-VQTVFSHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVA 1932
Query 2417 RATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQ 2476
R+ R E + +V G ++ +VY N G FCK HNW C NCD + +TF+S EVA +LS +
Sbjct 1933 RSNRQEVSVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEK 1992
Query 2477 FKRPINPTDQSSYIVDSVTVKNGSIHLYFDK-AGQKTYERHSLSHFVNLDNLR-ANNTKG 2534
KR + PT + ++VD + + ++L + K ++ F D L+ A K
Sbjct 1993 LKRHVKPTAYAYHVVDEACLVDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKE 2052
Query 2535 SLPINVIVFDGKSKCEESSA------KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAV 2588
+L I DG C SA K+A++YY+Q +C+PIL+LDQAL +
Sbjct 2053 ALKCEQISNDGFIVCNTQSAHALEEAKNAAIYYAQYLCKPILILDQALYEQL-------- 2104
Query 2589 KMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVET 2648
V K+++ + L+ +S+D + + + + S +
Sbjct 2105 ---------------VVEPVSKSVIDKVCSILSSIISVDTAALNYKAGTLRDALLSITKD 2149
Query 2649 KDVVECLKLSHQSDIEVTGDSCNNYMLTY-NKVENMTPRDLGACIDCSARHINAQVAKSH 2707
++ V+ H D++ TGD N + +Y +TPRD G I+ A N +V +
Sbjct 2150 EEAVDMAIFCHNHDVDYTGDGFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAP 2209
Query 2708 NIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL--KGGKI 2765
++W + + LS+ K + SA K+ + F +T + +QV+ T K+ + K G I
Sbjct 2210 --PVVWKFSELIKLSDSCLKYLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGI 2267
Query 2766 VNN---WLKQLIKVTLVFLF-----VAAIFYLITPVHVMSKHTDFSS--EIIGYKAIDGG 2815
V+ K K L+F + +Y+ + D +S + G+K ID G
Sbjct 2268 VSGTFKCFKSYFKWLLIFYILFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKG 2327
Query 2816 VTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILR 2875
V R+I DTCF+NK +FD ++ G Y N + CP++ AVI + G V G+PG +
Sbjct 2328 VLREIVPEDTCFSNKFVNFDAFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSW 2383
Query 2876 TTNG-DFLH---------FLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDA 2925
+G F+H ++P F+ + YT +I F TS + +A C ++ A
Sbjct 2384 VMDGVMFIHMTQTERKPWYIPTWFNRE-IVGYTQDSIITEGSFYTSIALFSARC-LYLTA 2441
Query 2926 SGKPVPYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYC 2984
S P YC++ N G++ + S+ P Y +G + P L V DS YC
Sbjct 2442 SNTPQLYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQILHTPYVVKFVSDS-YC 2500
Query 2985 RHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDIS 3044
R CE + G CVS + +WVL ND Y S PGVFCG L+ +M + + +I
Sbjct 2501 RGSVCEYTRPGYCVSLNPQWVLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIY 2559
Query 3045 ASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGV 3104
+ ++ +VV + ++F+ F Y+ V L+++++ +LC+ S L +
Sbjct 2560 MQLATMFLILVVVVLIFAMVIKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVI 2619
Query 3105 YSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAY---IICISTKHFYWFFSNYL 3161
V+Y Y + + + + H + F +VP W+ Y II + T F W +
Sbjct 2620 LLVLYCYASLVTSRNTVIIMHCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTK 2679
Query 3162 KRRVVFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGA 3220
R +++G F ++ AA TF++ ++KL +++ ++ YL+ Y + KY+SG
Sbjct 2680 NTRKLYDGNEFVGNYDLAAKSTFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGT 2736
Query 3221 MDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCM 3280
Y +A LA AL+ + NSG +++Y PP+ SI + LQSGF+K+ PS VE C+
Sbjct 2737 GSEQDYLQACRAWLAYALDQYRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCI 2796
Query 3281 VQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGN-VQLR 3339
V V+ LNGLWL D +YCPRHV+ + D+L +NH F V + V L
Sbjct 2797 VSVSYRGNNLNGLWLGDTIYCPRHVL---GKFSGDQWNDVLNLANNHEFEVTTQHGVTLN 2853
Query 3340 VIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTI 3399
V+ ++ VL L+ AN +TPKYKF++ G +F++ Y G+ G+Y MR N TI
Sbjct 2854 VVSRRLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTI 2913
Query 3400 KGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGT 3459
+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G FYG +VD + AQ
Sbjct 2914 RASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPP 2973
Query 3460 DTTITVNVLAWLYAAVINGDRW------FLNRFTTTLNDFNLVAMKYNYEPLTQDHVDIL 3513
D +T N++AWLYAA+I+ +L T +++D+N A + P + +
Sbjct 2974 DNLVTNNIVAWLYAAIISVKESSFSLPKWLESTTVSVDDYNKWAGDNGFTPFSTST--AI 3031
Query 3514 GPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVK 3573
LSA TG+ V + ++ + + G ILG EDE TP V Q GV QS+
Sbjct 3032 TKLSAITGVDVCKLLRTIM-VKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSFV 3090
Query 3574 RTIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 3630
R + W +L L L +V T L F++Y L A+ I+ + VK
Sbjct 3091 RKAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFT------VK 3143
Query 3631 HKHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRIMTWLDM--VDTSL------- 3674
H A++ FLLP+L TV A +Y + + V+ + W D DT +
Sbjct 3144 HVMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPL 3203
Query 3675 ---SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQA 3730
+ FK ++ C M + LL+L + ++T N LT + GN
Sbjct 3204 VLYTAFKCVQGCYMNSFNTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN----- 3251
Query 3731 ISMWALIISVTSNYSGVVTTVMFLARGIVFMC----VEYCPIFFITGNTLQCIMLVYCFL 3786
W L + + L VF C + YC ++ L +M+ +
Sbjct 3252 ---WELFFELVHTTVLANVSSNSLIGLFVFKCAKWMLYYCNATYLNNYVLMAVMVN--CI 3306
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G
Sbjct 3307 GWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQG 3366
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG + +ATVQ+K+SDVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E
Sbjct 3367 IGGDRVLPIATVQAKLSDVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGE 3426
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
+ ++ +L L + +D+++ C+++L LQ++ EFS +PSYA + A+ YE+
Sbjct 3427 CMDNLLGMLITLFCIDSTIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEK 3486
Query 3967 AVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKR 4022
+ + G ++ L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+R
Sbjct 3487 VLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRR 3546
Query 4023 AKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKN 4082
AK+ S++ +LF+ML+K+D++ LN + + A G VPL +P+ + KL +VIPD T+
Sbjct 3547 AKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVK 3606
Query 4083 TCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-----NSPNLAWPLIVTALRANSA- 4136
+G TY++ +W I V+DAD + + + N+AWPL V R
Sbjct 3607 CVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNK 3666
Query 4137 --VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
V LQNNEL P ++ +C AG Q C+ ++ YY G V A+ S +LK A
Sbjct 3667 VDVVLQNNELMPHGVKTKACVAGVDQAHCSVES-KCYYTNISGNSVVAAITSSNPNLKVA 3725
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
F G IY +L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+
Sbjct 3726 SFLNEAGN-QIYVDLDPPCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQS 3784
Query 4255 -GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
G+ TE +LS C+FAVD A Y Y+A+G QP+ NCVKML H G+G AIT P
Sbjct 3785 KGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPS 3844
Query 4314 ANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
DQ+S+GGAS CLYCR HI HP N G C KG +VQIPTT DPVGF L+N V
Sbjct 3845 PTPDQDSYGGASVCLYCRAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKV 3903
Query 4370 CTVCGMWKGYGCSCDQLREP--MLQSAD-----AQSFLNRVCGVSAARLTPCGTGTSTDV 4422
CTVC W GYGC CD LR+P +QS +++LNRV G S ARL P +G DV
Sbjct 3904 CTVCQCWIGYGCQCDSLRQPKSSVQSVAGASDFDKNYLNRVRGSSEARLIPLASGCDPDV 3963
Query 4423 VYRAFDIYNDKVAGFAKFLKTNCCRFQEK--DEDDNL--IDSYFVVKRHTFSNYQHEETI 4478
V RAFD+ N + AG + LK NC RFQE ED NL +DSYFVVK+ T SNY+HE++
Sbjct 3964 VKRAFDVCNKESAGMFQNLKRNCARFQELRDTEDGNLEYLDSYFVVKQTTPSNYEHEKSC 4023
Query 4479 YNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEIL 4538
Y LK A HDFF F + + +ISRQRLTKYTM D YALRHFD +C+ LKEIL
Sbjct 4024 YEDLKS-EVTADHDFFVFNKN---IYNISRQRLTKYTMMDFCYALRHFDPKDCEVLKEIL 4079
Query 4539 VTYNCCDD---DYFN-KKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIV 4594
VTY C +D +F KDWYD +EN + A +G VR+ALL ++F + M G V
Sbjct 4080 VTYGCIEDYHPKWFEENKDWYDPIENSKYYVMLAKMGPIVRRALLNAIEFGNLMVEKGYV 4139
Query 4595 GVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLT 4654
GV+TLDNQDLNG +YDFGDF +T PG+GVPV D+YYS +MPI+ +T AL E + + D+
Sbjct 4140 GVITLDNQDLNGKFYDFGDFQKTAPGAGVPVFDTYYSYMMPIIAMTDALAPERYFEYDVH 4199
Query 4655 KPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFP 4714
K Y +DLLKYD+TEE+ +LF +YFKYWDQ YHPNC +C DDRC++HCANFN+LFST+ P
Sbjct 4200 KGYKSYDLLKYDYTEEKQELFQKYFKYWDQEYHPNCRDCSDDRCLIHCANFNILFSTLIP 4259
Query 4715 PTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHA 4774
TSFG L RK+FVDGVPF+ + GYH +ELGV+ NQD + S++ +L+ + DPA+
Sbjct 4260 QTSFGNLCRKVFVDGVPFIATCGYHSKELGVIMNQDNTMSFSKMGLSQLMQFVGDPALLV 4319
Query 4775 ASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFF 4834
+ N L+D RT+CFSV ALT+ + QTVKPG+FNKDFYDFA G FKEGSS+ LKHFF+
Sbjct 4320 GTSNNLVDLRTSCFSVCALTSGITHQTVKPGHFNKDFYDFAEKAGMFKEGSSIPLKHFFY 4379
Query 4835 AQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSA 4894
Q GNAAI+DYDYYRYN PTM DI QLLF +EV KYF+CY+GGCI A+QV+VNNLDKSA
Sbjct 4380 PQTGNAAINDYDYYRYNRPTMFDICQLLFCLEVTSKYFECYEGGCIPASQVVVNNLDKSA 4439
Query 4895 GFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSI 4954
G+PFNK+GKARLYY+ MS E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI
Sbjct 4440 GYPFNKFGKARLYYE-MSLEEQDQLFEITKKNVLPTITQMNLKYAISAKNRARTVAGVSI 4498
Query 4955 CSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKC 5014
STMTNRQFHQK+LKSI TR A+VVIGT+KFYGGW NML+ + VE+P LMGWDYPKC
Sbjct 4499 LSTMTNRQFHQKILKSIVNTRNASVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKC 4558
Query 5015 DRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSS 5074
DRAMPN+LRI ASLVLARKHT CCS S R YRL NECAQVLSE V+ G +YVKPGGTSS
Sbjct 4559 DRAMPNLLRIAASLVLARKHTNCCSWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSS 4618
Query 5075 GDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFV 5134
GDATTAYANSVFNI QA +ANV LLS I +++LQ+ LY+ +YR + D FV
Sbjct 4619 GDATTAYANSVFNIIQATSANVARLLSVITRDIVYDNIKSLQYELYQQVYRRVNFDPAFV 4678
Query 5135 NEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTE 5194
+FY+YL K+FS+MILSDD VVC+N+T A QGLVA I F+ VLYYQNNVFM+++KCW E
Sbjct 4679 EKFYSYLCKNFSLMILSDDGVVCYNNTLAKQGLVADISGFREVLYYQNNVFMADSKCWVE 4738
Query 5195 TDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSL 5254
DL KGPHEFCSQHTMLV+ + YLPYPDPSRILGA FVDD+ KT+ ++ER+++L
Sbjct 4739 PDLEKGPHEFCSQHTMLVEVDGEPKYLPYPDPSRILGACVFVDDVDKTEPVAVMERYIAL 4798
Query 5255 AIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYE 5314
AIDAYPL H N+EY VF + L YIRKL+ EL+ +ML YS ++ D S++WE EFYE
Sbjct 4799 AIDAYPLVHHENEEYKKVFFVLLAYIRKLYQELSQNMLMDYSFVMDIDKGSKFWEQEFYE 4858
Query 5315 AMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVC 5374
MY T LQ+ G CV+CNSQT LRCG CIR+PFLCCKCCYDHV+ T HK VLS+NPY+C
Sbjct 4859 NMYRAPTTLQSCGVCVVCNSQTILRCGNCIRKPFLCCKCCYDHVMHTDHKNVLSINPYIC 4918
Query 5375 NAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIA 5434
+ GC DVT+LYLGGMSY+C +HKP +S PL +NG VFG+Y+ C GS+NV DFN +A
Sbjct 4919 SQLGCGEADVTKLYLGGMSYFCGNHKPKLSIPLVSNGTVFGIYRANCAGSENVDDFNQLA 4978
Query 5435 TCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVG 5494
T +W+ YILAN C++ L+ FAAET+KATEE K + A VREV SDREL LSWE G
Sbjct 4979 TTNWSIVEPYILANRCSDSLRRFAAETVKATEELHKQQFASAEVREVFSDRELILSWEPG 5038
Query 5495 KPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSH 5554
K RPPLNRNYVFTGY T+ SKVQ+G++TFEKG+ D V Y+ T+T KL+VGD FVLTSH
Sbjct 5039 KTRPPLNRNYVFTGYHFTRTSKVQLGDFTFEKGEGKDVVYYKATSTAKLSVGDIFVLTSH 5098
Query 5555 TVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSH 5614
V+ L APTL PQ+ + R L P + + + F +N+ Y VG QK +T+QGPPG+GKSH
Sbjct 5099 NVVSLVAPTLCPQQTFSRFVNLRPNVMVPECFVNNIPLYHLVGKQKRTTVQGPPGSGKSH 5158
Query 5615 FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNS 5674
FAIGLA+Y+ SAR+V+TACSHAAVDALCEKA K+L +D C+RI+P R V+CF KFK N
Sbjct 5159 FAIGLAVYFSSARVVFTACSHAAVDALCEKAFKFLKVDDCTRIVPQRTTVDCFSKFKAND 5218
Query 5675 TLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRT 5734
T ++Y+F T+NALPE + DI++ DE+SM TNY+LS +N ++ ++ VY+GDPAQLPAPRT
Sbjct 5219 TGKKYIFSTINALPEVSCDILLVDEVSMLTNYELSFINGKINYQYVVYVGDPAQLPAPRT 5278
Query 5735 LLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ 5794
LL G+L P+ +N V LM + PD+FL C RCP EIVDTVS LVYD K A+ +S +
Sbjct 5279 LLN-GSLSPKDYNVVTNLMVCVKPDIFLAKCYRCPKEIVDTVSTLVYDGKFIANNPESRE 5337
Query 5795 CFKMFYKG---VITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILG 5851
CFK+ + H+ SA N Q+ V++F+ RN WR+A+FISPYN+ N A ++LG
Sbjct 5338 CFKVIVNNGNSDVGHESGSAYNTTQLEFVKDFVCRNKQWREAIFISPYNAMNQRAYRMLG 5397
Query 5852 LPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRD-LYDKLQ 5910
L QTVDSSQGSEYDYVIF T ++ H+ N+NRFNVA+TRAK GIL +M RD LY L+
Sbjct 5398 LNVQTVDSSQGSEYDYVIFCVTADSQHALNINRFNVALTRAKRGILVVMRQRDELYSALK 5457
Query 5911 FTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGI 5970
FT L+ + +LQ TGLFK C+K +G+HP A T ++ +K + +
Sbjct 5458 FTELD----SETSLQG---TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNV 5510
Query 5971 P--KDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGT 6028
++TY+ LIS++GFKM+ V G NMFITR+EAIR+VR W+GFDVE HA +GT
Sbjct 5511 EAGSEITYKHLISLLGFKMSVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGT 5570
Query 6029 NLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVR 6088
NLP Q+GFSTG + V P G VDT +F V++K PPG+QF HL L PW+V+R
Sbjct 5571 NLPFQVGFSTGADFVVTPEGLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIR 5630
Query 6089 IKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDT 6148
+IVQML+D L N+SD VVFV W HG ELT+++YFVKIG E+ C C RAT F++ +
Sbjct 5631 PRIVQMLADNLCNVSDCVVFVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQA 5689
Query 6149 YACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVH 6208
YACW H +GFD+VYNP ++D+QQWG++GNLQ NHDL+C VHG+AHVAS DAIMTRCLA++
Sbjct 5690 YACWKHCLGFDFVYNPLLVDIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAIN 5749
Query 6209 ECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQ 6268
F + V+W + YP I +E ++N++CR +Q M + A + A K V++DIGNPK IKCV +
Sbjct 5750 NAFCQDVNWDLTYPHIANEDEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRR 5809
Query 6269 ADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDT 6328
DV ++FYD P + E Y Y H DKF DG+C+FWNCNVD YP NS+VCR+DT
Sbjct 5810 GDVNFRFYDKNPIVRNVKQFE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDT 5866
Query 6329 RVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDI 6388
R LS NLPGC+GGSLYVNKHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+
Sbjct 5867 RNLSVFNLPGCNGGSLYVNKHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ- 5925
Query 6389 DYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF 6448
D V L + CIT+CN+GGAVC+ HA Y ++ +YN ++AGF+ WV + + YNLW +F
Sbjct 5926 DLVSLATKDCITKCNIGGAVCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSF 5985
Query 6449 TRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFE 6508
+ LQS++N+A+N+ GH+D GE+P I + V+ GV+ +F N+TTLP +VAFE
Sbjct 5986 SALQSIDNIAYNMYKGGHYDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFE 6045
Query 6509 LWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETIC 6568
L+AKRNI+ +P +IL LGVD+ VIWDY P + +T+ VC+ TDI
Sbjct 6046 LYAKRNIRTLPNNRILKGLGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEPN------ 6099
Query 6569 APLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQ 6627
L V +D R G F A N VL++ K P + NG+ L A
Sbjct 6100 -GLVVLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---N 6154
Query 6628 FNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHI 6687
YK+V+G LP T TQ R+ + F+PRS +E DFL ++ + F+ERY + +HI
Sbjct 6155 LYVYKRVNGAFVTLPNTINTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHI 6213
Query 6688 VYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVI 6747
+YG+ QLGGLH +IG+ + + + + DS V + + GS K VC+V+
Sbjct 6214 LYGEVDKPQLGGLHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVLSDNGSYKQVCTVV 6273
Query 6748 DLLLDDFV----EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAW 6803
DLLLDDF+ I+K + SKVV V+IDY I+FM W +DG ++T YP+LQS+ W
Sbjct 6274 DLLLDDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQSA--W 6330
Query 6804 QPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNM 6863
G MP LYK+Q ++E C++ NYG TLP GI+MNVAKYTQLCQYL+ T+ VP+NM
Sbjct 6331 TCGYNMPELYKVQNCVMEPCNIPNYGVGITLPSGILMNVAKYTQLCQYLSKTTICVPHNM 6390
Query 6864 RVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWD 6923
RV+HFGAGSDKGVAPG+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC +T +K+D
Sbjct 6391 RVMHFGAGSDKGVAPGSTVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYNTEHKFD 6450
Query 6924 LIISDMY---DPKTKNVT-KENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLY 6979
L+ISDMY D K K+ N+ + F Y+ F++ LALGGS A+K+TE SW+ LY
Sbjct 6451 LVISDMYTDNDSKRKHEGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSWHEVLY 6510
Query 6980 KLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKP-REQIDGYVMHANYIFWRNTNPIQLS 7038
+ AWWT F T VNASSSEAFLIG NYLG + ++ G +HANYIFWRN N +Q S
Sbjct 6511 DIAQDCAWWTMFCTAVNASSSEAFLIGVNYLGASEKVKVSGKTLHANYIFWRNCNYLQTS 6570
Query 7039 SYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLV 7094
+YS+FD++KF L+L+ T V++LK Q D++ +L+ G+L++R+ +SD V
Sbjct 6571 AYSIFDVAKFDLRLKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 6626
Score = 145 bits (367), Expect = 1e-32, Method: Composition-based stats.
Identities = 69/328 (21%), Positives = 119/328 (36%), Gaps = 29/328 (9%)
Query 925 YPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWL--DD 982
P + E+ Q E D A + EE +E L
Sbjct 909 EPVENSTGSSKTMTEQVVVEDQELPVVEQDQDVVVYTPTDLEVAKETAEEVDEFILIFAV 968
Query 983 DSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPV---VQTIEVNSFSGYLKLTDNVY 1039
++ V Q+DG++ Q + I V+PQ E + T E F Y ++
Sbjct 969 PKEEVVSQKDGAQIKQ----EPIQVVKPQREKKAKKFKVKPATCEKPKFLEYKTCVGDLT 1024
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKV 1099
+ A ++E K+ +VNAAN ++ HG GVA A+ +DY+ +GP +
Sbjct 1025 VVIAKALDEFKEF---CIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ- 1080
Query 1100 GGSCVLSGHNLAKHCL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGA 1156
V C+ +VVGP + L +AY+N V+ + P+LS GIFG
Sbjct 1081 --RLVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGV 1138
Query 1157 D---PIHSLRVCVDTVRTNVYLAVFDKNLYDKL------VSSFL--EMKSEKQVEQKIAE 1205
D I ++R + V L + D + +L + + + K +
Sbjct 1139 DFKMSIDAMREAFEGCTIRVLLFSLSQEHIDYFDVTCKQKTIYLTEDGVKYRSIVLKPGD 1198
Query 1206 IPKEEVKPFITESKPSVEQRKQDDKKIK 1233
+ + + +D + +
Sbjct 1199 SLGQFGQVYAKNKIVFTADDVEDKEILY 1226
Score = 45.1 bits (105), Expect = 0.036, Method: Composition-based stats.
Identities = 50/374 (13%), Positives = 111/374 (30%), Gaps = 20/374 (5%)
Query 524 GEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA 583
G I L A ++ V + + + + L + D ++L
Sbjct 374 GVTPEINDGLILAAIYSSFSVSELVTALKK--GEPFKFLGHKFVYAKDAAVSFTLAKAAT 431
Query 584 MMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLR 643
+ L + V+ + + + ++ +G V + V ++ + V
Sbjct 432 IADVLRLFQSARVIAEDVWSSFTEKSFEFWKLAYGKVRNLEEFVKTYVCKAQMSIVILAA 491
Query 644 DGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII-IGGAKLKA 702
E + + + +G + + F + + + ++ + G
Sbjct 492 VLGEDIWHLVSQVIYKLGVLFTKVVDFCDKHWKGFCVQLKRAKLIVTETFCVLKGVAQHC 551
Query 703 LNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGD 762
L + ++KC R LL +I+ +G+ + + + V G
Sbjct 552 FQLLLDAIHSLYKSFKKCALGRIHGDLLFWKGGVHKIVQ-DGDEIWFDAIDSVDVEDLGV 610
Query 763 LQPLEQPTSEAVEAPLV----GTPVCING-----LMLLEIKDTEKYCALAPNMMVTNNTF 813
+Q + L G V I + KD Y + N
Sbjct 611 VQEKSIDFEVCDDVTLPENQPGHMVQIEDDGKNYMFFRFKKDENIYYTPMSQLGAINVVC 670
Query 814 TLKGGAPTKVTFGDDTVIEV--QGYKSVNITFELD-ERIDKVLNEKCS-AYTVELGTEVN 869
VTFG+ TV E+ + ++ E E + + + V+ V
Sbjct 671 K---AGGKTVTFGETTVQEIPPPDVVPIKVSIECCGEPWNTIFKKAYKEPIEVDTDLTVE 727
Query 870 EFACVVADAVIKTL 883
+ V+ + + L
Sbjct 728 QLLSVIYEKMCDDL 741
>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep
PE=3 SV=1
Length=6629
Score = 6688 bits (17352), Expect = 0.0, Method: Composition-based stats.
Identities = 2367/5696 (42%), Positives = 3294/5696 (58%), Gaps = 376/5696 (7%)
Query 1549 EVITFDNLKTLLSLREV--RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTK 1606
V+ F + + +V + ++ T D + + V+ + G QFG Y V
Sbjct 1157 RVLLFSLSQEHIDYFDVTCKQKTIYLTEDGVKYRSIVLKPGDSLG-QFGQVYAKNKIV-- 1213
Query 1607 IKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTS 1666
+ + + YV D ++ EYY D Y+ L +KW +
Sbjct 1214 FTADDVEDKEILYVPTTDKSI----LEYYG-LDAQKYVIYLQTL--AQKWNVQYRDNFLI 1266
Query 1667 IKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELG 1726
++W D NC++++A++ LQ +++F L +A+ + G+ +F A A C VG+
Sbjct 1267 LEWRDGNCWISSAIVLLQAAKIRFK-GFLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFS 1325
Query 1727 DVRETMSYLFQHANLDSCKRVLNV-VCKTCGQQQTTLKGVEAVM-YMGTLSYEQFKKGVQ 1784
D ++ L +H + D L V CG + L+G+EA + + + FK
Sbjct 1326 DANWLLANLAEHFDADYTNAFLKKRVSCNCGIKSYELRGLEACIQPVRATNLLHFKTQYS 1385
Query 1785 IPCTCGKQATKYLVQQESPFVMMSAP--PAQYELKHGTFTCASEYTGNYQCGH-YKHITS 1841
TCG T +++ P++++ A PA + + G+ GH Y
Sbjct 1386 NCPTCGANNTDEVIEASLPYLLLFATDGPATVDCDEDAVGT-VVFVGSTNSGHCYTQA-- 1442
Query 1842 KETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYK 1901
D + K P Y ++ K + + N
Sbjct 1443 --AGQAFDNLAKDRKFGKKSPYITAMYTRFAFKNETSLPVAKQSKGKSKSVKEDVSNL-- 1498
Query 1902 KDNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFP 1961
ASFDN D Q Y LKV P
Sbjct 1499 ----------------ATSSKASFDNL----------TDFEQW--YDSNIYESLKVQESP 1530
Query 1962 DLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVET 2021
D ++ Y T + + P T +R + S +
Sbjct 1531 D--------NFDKYVS------------------FTTKEDSKLPLTLKVRGIKSVVDFRS 1564
Query 2022 SNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVK---------TTEVV 2072
+ F + D PV V++ +++ +E N + +
Sbjct 1565 KDGFIYKLTPDTD------ENSKAPVYYPVLDAISLKAIWVEGNANFVVGHPNYYSKSLH 1618
Query 2073 GDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNS 2132
+ A N +K+ +++G + ++ + KPN L R+ + A G + V +
Sbjct 1619 IPTFWENAENFVKMGDKIGGVTMGLWRAEH----LNKPN-LERIFNIAKKAIVGSSVVTT 1673
Query 2133 VPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVC--------TNYMPYFF-TLLLQLCTFT 2183
I A +KV +T + +C P F TL+ L F
Sbjct 1674 QCGKLIGKAATFIADKVGGGVVRNITDSIKGLCGITRGHFERKMSPQFLKTLMFFLFYFL 1733
Query 2184 RSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSL 2243
+++ + AS T + K + ++ +I+WF+ S +
Sbjct 1734 KASVKSVVASYKTVLCKVVLATL----------------------LIVWFVYTS---NPV 1768
Query 2244 IYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPS 2303
+++ + + L S C Y++ +S + YC C VCL DSL Y
Sbjct 1769 MFTGIRV---LDFLFEGSLCGPYKDYGKDS--FDVLRYCADDFICRVCLHDKDSLHLYKH 1823
Query 2304 LETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAIMQLFFSYFAVHFISN 2361
+++ A G + W Y++F F V G I Y + + N
Sbjct 1824 AYSVEQVYKD-----AASGFIFNWNWLYLVFLILFVKPVAGFVII-----CYCVKYLVLN 1873
Query 2362 SWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVVDGCNSSTCMMCYKRN 2416
S ++ + + + + + F + +Y W Y VH + C TC +C +
Sbjct 1874 STVLQTGVCFLDWF-VQTVFSHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVA 1932
Query 2417 RATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQ 2476
R+ R E + +V G ++ +VY N G FCK HNW C NCD + +TF+S EVA +LS +
Sbjct 1933 RSNRQEVSVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEK 1992
Query 2477 FKRPINPTDQSSYIVDSVTVKNGSIHLYFDK-AGQKTYERHSLSHFVNLDNLR-ANNTKG 2534
KR + PT + ++VD + + ++L + K ++ F D L+ A K
Sbjct 1993 LKRHVKPTAYAYHVVDEACLVDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKE 2052
Query 2535 SLPINVIVFDGKSKCEESSA------KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAV 2588
+L I DG C SA K+A++YY+Q +C+PIL+LDQAL +
Sbjct 2053 ALKCEQISNDGFIVCNTQSAHALEEAKNAAIYYAQYLCKPILILDQALYEQL-------- 2104
Query 2589 KMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVET 2648
V K+++ + L+ +S+D + + + + S +
Sbjct 2105 ---------------VVEPVSKSVIDKVCSILSSIISVDTAALNYKAGTLRDALLSITKD 2149
Query 2649 KDVVECLKLSHQSDIEVTGDSCNNYMLTY-NKVENMTPRDLGACIDCSARHINAQVAKSH 2707
++ V+ H D++ TGD N + +Y +TPRD G I+ A N +V +
Sbjct 2150 EEAVDMAIFCHNHDVDYTGDGFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAP 2209
Query 2708 NIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL--KGGKI 2765
++W + + LS+ K + SA K+ + F +T + +QV+ T K+ + K G I
Sbjct 2210 --PVVWKFSELIKLSDSCLKYLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGI 2267
Query 2766 VNN---WLKQLIKVTLVFLF-----VAAIFYLITPVHVMSKHTDFSS--EIIGYKAIDGG 2815
V+ K K L+F + +Y+ + D +S + G+K ID G
Sbjct 2268 VSGTFKCFKSYFKWLLIFYILFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKG 2327
Query 2816 VTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILR 2875
V R+I DTCF+NK +FD ++ G Y N + CP++ AVI + G V G+PG +
Sbjct 2328 VLREIVPEDTCFSNKFVNFDAFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSW 2383
Query 2876 TTNG-DFLH---------FLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDA 2925
+G F+H ++P F+ + YT +I F TS + +A C ++ A
Sbjct 2384 VMDGVMFIHMTQTERKPWYIPTWFNRE-IVGYTQDSIITEGSFYTSIALFSARC-LYLTA 2441
Query 2926 SGKPVPYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYC 2984
S P YC++ N G++ + S+ P Y +G + P L V DS YC
Sbjct 2442 SNTPQLYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQILHTPYVVKFVSDS-YC 2500
Query 2985 RHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDIS 3044
R CE + G CVS + +WVL ND Y S PGVFCG L+ +M + + +I
Sbjct 2501 RGSVCEYTRPGYCVSLNPQWVLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIY 2559
Query 3045 ASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGV 3104
+ ++ +VV + ++F+ F Y+ V L+++++ +LC+ S L +
Sbjct 2560 MQLATMFLILVVVVLIFAMVIKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVI 2619
Query 3105 YSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAY---IICISTKHFYWFFSNYL 3161
V+Y Y + + + + H + F +VP W+ Y II + T F W +
Sbjct 2620 LLVLYCYASLVTSRNTVIIMHCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTK 2679
Query 3162 KRRVVFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGA 3220
R +++G F ++ AA TF++ ++KL +++ ++ YL+ Y + KY+SG
Sbjct 2680 NTRKLYDGNEFVGNYDLAAKSTFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGT 2736
Query 3221 MDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCM 3280
Y +A LA AL+ + NSG +++Y PP+ SI + LQSGF+K+ PS VE C+
Sbjct 2737 GSEQDYLQACRAWLAYALDQYRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCI 2796
Query 3281 VQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGN-VQLR 3339
V V+ LNGLWL D +YCPRHV+ + D+L +NH F V + V L
Sbjct 2797 VSVSYRGNNLNGLWLGDTIYCPRHVL---GKFSGDQWNDVLNLANNHEFEVTTQHGVTLN 2853
Query 3340 VIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTI 3399
V+ ++ VL L+ AN +TPKYKF++ G +F++ Y G+ G+Y MR N TI
Sbjct 2854 VVSRRLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTI 2913
Query 3400 KGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGT 3459
+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G FYG +VD + AQ
Sbjct 2914 RASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPP 2973
Query 3460 DTTITVNVLAWLYAAVINGDRW------FLNRFTTTLNDFNLVAMKYNYEPLTQDHVDIL 3513
D +T N++AWLYAA+I+ +L T +++D+N A + P + +
Sbjct 2974 DNLVTNNIVAWLYAAIISVKESSFSLPKWLESTTVSVDDYNKWAGDNGFTPFSTST--AI 3031
Query 3514 GPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVK 3573
LSA TG+ V + ++ + + G ILG EDE TP V Q GV QS+
Sbjct 3032 TKLSAITGVDVCKLLRTIM-VKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSFV 3090
Query 3574 RTIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 3630
R + W +L L L +V T L F++Y L A+ I+ + VK
Sbjct 3091 RKAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFT------VK 3143
Query 3631 HKHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRIMTWLDM--VDTSL------- 3674
H A++ FLLP+L TV A +Y + + V+ + W D DT +
Sbjct 3144 HVMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPL 3203
Query 3675 ---SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQA 3730
+ FK ++ C M + LL+L + ++T N LT + GN
Sbjct 3204 VLYTAFKCVQGCYMNSFNTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN----- 3251
Query 3731 ISMWALIISVTSNYSGVVTTVMFLARGIVFMC----VEYCPIFFITGNTLQCIMLVYCFL 3786
W L + + L VF C + YC ++ L +M+ +
Sbjct 3252 ---WELFFELVHTTVLANVSSNSLIGLFVFKCAKWMLYYCNATYLNNYVLMAVMVN--CI 3306
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G
Sbjct 3307 GWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQG 3366
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG + +ATVQ+K+SDVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E
Sbjct 3367 IGGDRVLPIATVQAKLSDVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGE 3426
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
+ ++ +L L + +D+++ C+++L LQ++ EFS +PSYA + A+ YE+
Sbjct 3427 CMDNLLGMLITLFCIDSTIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEK 3486
Query 3967 AVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKR 4022
+ + G ++ L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+R
Sbjct 3487 VLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRR 3546
Query 4023 AKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKN 4082
AK+ S++ +LF+ML+K+D++ LN + + A G VPL +P+ + KL +VIPD T+
Sbjct 3547 AKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVK 3606
Query 4083 TCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-----NSPNLAWPLIVTALRANSA- 4136
+G TY++ +W I V+DAD + + + N+AWPL V R
Sbjct 3607 CVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNK 3666
Query 4137 --VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
V LQNNEL P ++ +C AG Q C+ ++ YY G V A+ S +LK A
Sbjct 3667 VDVVLQNNELMPHGVKTKACVAGVDQAHCSVES-KCYYTNISGNSVVAAITSSNPNLKVA 3725
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
F G IY +L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+
Sbjct 3726 SFLNEAGN-QIYVDLDPPCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQS 3784
Query 4255 -GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
G+ TE +LS C+FAVD A Y Y+A+G QP+ NCVKML H G+G AIT P
Sbjct 3785 KGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPS 3844
Query 4314 ANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
DQ+S+GGAS CLYCR HI HP N G C KG +VQIPTT DPVGF L+N V
Sbjct 3845 PTPDQDSYGGASVCLYCRAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKV 3903
Query 4370 CTVCGMWKGYGCSCDQLREP--MLQSAD-----AQSFLNRVCGVSAARLTPCGTGTSTDV 4422
CTVC W GYGC CD LR+P +QS +++LNRV G S ARL P +G DV
Sbjct 3904 CTVCQCWIGYGCQCDSLRQPKSSVQSVAGASDFDKNYLNRVRGSSEARLIPLASGCDPDV 3963
Query 4423 VYRAFDIYNDKVAGFAKFLKTNCCRFQEK--DEDDNL--IDSYFVVKRHTFSNYQHEETI 4478
V RAFD+ N + AG + LK NC RFQE ED NL +DSYFVVK+ T SNY+HE++
Sbjct 3964 VKRAFDVCNKESAGMFQNLKRNCARFQELRDTEDGNLEYLDSYFVVKQTTPSNYEHEKSC 4023
Query 4479 YNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEIL 4538
Y LK A HDFF F + + +ISRQRLTKYTM D YALRHFD +C+ LKEIL
Sbjct 4024 YEDLKS-EVTADHDFFVFNKN---IYNISRQRLTKYTMMDFCYALRHFDPKDCEVLKEIL 4079
Query 4539 VTYNCCDD---DYFN-KKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIV 4594
VTY C +D +F KDWYD +EN + A +G VR+ALL ++F + M G V
Sbjct 4080 VTYGCIEDYHPKWFEENKDWYDPIENSKYYVMLAKMGPIVRRALLNAIEFGNLMVEKGYV 4139
Query 4595 GVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLT 4654
GV+TLDNQDLNG +YDFGDF +T PG+GVPV D+YYS +MPI+ +T AL E + + D+
Sbjct 4140 GVITLDNQDLNGKFYDFGDFQKTAPGAGVPVFDTYYSYMMPIIAMTDALAPERYFEYDVH 4199
Query 4655 KPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFP 4714
K Y +DLLKYD+TEE+ +LF +YFKYWDQ YHPNC +C DDRC++HCANFN+LFST+ P
Sbjct 4200 KGYKSYDLLKYDYTEEKQELFQKYFKYWDQEYHPNCRDCSDDRCLIHCANFNILFSTLIP 4259
Query 4715 PTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHA 4774
TSFG L RK+FVDGVPF+ + GYH +ELGV+ NQD + S++ +L+ + DPA+
Sbjct 4260 QTSFGNLCRKVFVDGVPFIATCGYHSKELGVIMNQDNTMSFSKMGLSQLMQFVGDPALLV 4319
Query 4775 ASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFF 4834
+ N L+D RT+CFSV ALT+ + QTVKPG+FNKDFYDFA G FKEGSS+ LKHFF+
Sbjct 4320 GTSNNLVDLRTSCFSVCALTSGITHQTVKPGHFNKDFYDFAEKAGMFKEGSSIPLKHFFY 4379
Query 4835 AQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSA 4894
Q GNAAI+DYDYYRYN PTM DI QLLF +EV KYF+CY+GGCI A+QV+VNNLDKSA
Sbjct 4380 PQTGNAAINDYDYYRYNRPTMFDICQLLFCLEVTSKYFECYEGGCIPASQVVVNNLDKSA 4439
Query 4895 GFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSI 4954
G+PFNK+GKARLYY+ MS E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI
Sbjct 4440 GYPFNKFGKARLYYE-MSLEEQDQLFEITKKNVLPTITQMNLKYAISAKNRARTVAGVSI 4498
Query 4955 CSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKC 5014
STMTNRQFHQK+LKSI TR A+VVIGT+KFYGGW NML+ + VE+P LMGWDYPKC
Sbjct 4499 LSTMTNRQFHQKILKSIVNTRNASVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKC 4558
Query 5015 DRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSS 5074
DRAMPN+LRI ASLVLARKHT CCS S R YRL NECAQVLSE V+ G +YVKPGGTSS
Sbjct 4559 DRAMPNLLRIAASLVLARKHTNCCSWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSS 4618
Query 5075 GDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFV 5134
GDATTAYANSVFNI QA +ANV LLS I +++LQ+ LY+ +YR + D FV
Sbjct 4619 GDATTAYANSVFNIIQATSANVARLLSVITRDIVYDNIKSLQYELYQQVYRRVNFDPAFV 4678
Query 5135 NEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTE 5194
+FY+YL K+FS+MILSDD VVC+N+T A QGLVA I F+ VLYYQNNVFM+++KCW E
Sbjct 4679 EKFYSYLCKNFSLMILSDDGVVCYNNTLAKQGLVADISGFREVLYYQNNVFMADSKCWVE 4738
Query 5195 TDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSL 5254
DL KGPHEFCSQHTMLV+ + YLPYPDPSRILGA FVDD+ KT+ ++ER+++L
Sbjct 4739 PDLEKGPHEFCSQHTMLVEVDGEPKYLPYPDPSRILGACVFVDDVDKTEPVAVMERYIAL 4798
Query 5255 AIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYE 5314
AIDAYPL H N+EY VF + L YIRKL+ EL+ +ML YS ++ D S++WE EFYE
Sbjct 4799 AIDAYPLVHHENEEYKKVFFVLLAYIRKLYQELSQNMLMDYSFVMDIDKGSKFWEQEFYE 4858
Query 5315 AMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVC 5374
MY T LQ+ G CV+CNSQT LRCG CIR+PFLCCKCCYDHV+ T HK VLS+NPY+C
Sbjct 4859 NMYRAPTTLQSCGVCVVCNSQTILRCGNCIRKPFLCCKCCYDHVMHTDHKNVLSINPYIC 4918
Query 5375 NAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIA 5434
+ GC DVT+LYLGGMSY+C +HKP +S PL +NG VFG+Y+ C GS+NV DFN +A
Sbjct 4919 SQLGCGEADVTKLYLGGMSYFCGNHKPKLSIPLVSNGTVFGIYRANCAGSENVDDFNQLA 4978
Query 5435 TCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVG 5494
T +W+ YILAN C++ L+ FAAET+KATEE K + A VREV SDREL LSWE G
Sbjct 4979 TTNWSIVEPYILANRCSDSLRRFAAETVKATEELHKQQFASAEVREVFSDRELILSWEPG 5038
Query 5495 KPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSH 5554
K RPPLNRNYVFTGY T+ SKVQ+G++TFEKG+ D V Y+ T+T KL+VGD FVLTSH
Sbjct 5039 KTRPPLNRNYVFTGYHFTRTSKVQLGDFTFEKGEGKDVVYYKATSTAKLSVGDIFVLTSH 5098
Query 5555 TVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSH 5614
V+ L APTL PQ+ + R L P + + + F +N+ Y VG QK +T+QGPPG+GKSH
Sbjct 5099 NVVSLVAPTLCPQQTFSRFVNLRPNVMVPECFVNNIPLYHLVGKQKRTTVQGPPGSGKSH 5158
Query 5615 FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNS 5674
FAIGLA+Y+ SAR+V+TACSHAAVDALCEKA K+L +D C+RI+P R V+CF KFK N
Sbjct 5159 FAIGLAVYFSSARVVFTACSHAAVDALCEKAFKFLKVDDCTRIVPQRTTVDCFSKFKAND 5218
Query 5675 TLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRT 5734
T ++Y+F T+NALPE + DI++ DE+SM TNY+LS +N ++ ++ VY+GDPAQLPAPRT
Sbjct 5219 TGKKYIFSTINALPEVSCDILLVDEVSMLTNYELSFINGKINYQYVVYVGDPAQLPAPRT 5278
Query 5735 LLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ 5794
LL G+L P+ +N V LM + PD+FL C RCP EIVDTVS LVYD K A+ +S +
Sbjct 5279 LLN-GSLSPKDYNVVTNLMVCVKPDIFLAKCYRCPKEIVDTVSTLVYDGKFIANNPESRE 5337
Query 5795 CFKMFYKG---VITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILG 5851
CFK+ + H+ SA N Q+ V++F+ RN WR+A+FISPYN+ N A ++LG
Sbjct 5338 CFKVIVNNGNSDVGHESGSAYNTTQLEFVKDFVCRNKQWREAIFISPYNAMNQRAYRMLG 5397
Query 5852 LPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRD-LYDKLQ 5910
L QTVDSSQGSEYDYVIF T ++ H+ N+NRFNVA+TRAK GIL +M RD LY L+
Sbjct 5398 LNVQTVDSSQGSEYDYVIFCVTADSQHALNINRFNVALTRAKRGILVVMRQRDELYSALK 5457
Query 5911 FTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGI 5970
FT L+ + +LQ TGLFK C+K +G+HP A T ++ +K + +
Sbjct 5458 FTELD----SETSLQG---TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNV 5510
Query 5971 P--KDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGT 6028
++TY+ LIS++GFKM+ V G NMFITR+EAIR+VR W+GFDVE HA +GT
Sbjct 5511 EAGSEITYKHLISLLGFKMSVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGT 5570
Query 6029 NLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVR 6088
NLP Q+GFSTG + V P G VDT +F V++K PPG+QF HL L PW+V+R
Sbjct 5571 NLPFQVGFSTGADFVVTPEGLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIR 5630
Query 6089 IKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDT 6148
+IVQML+D L N+SD VVFV W HG ELT+++YFVKIG E+ C C RAT F++ +
Sbjct 5631 PRIVQMLADNLCNVSDCVVFVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQA 5689
Query 6149 YACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVH 6208
YACW H +GFD+VYNP ++D+QQWG++GNLQ NHDL+C VHG+AHVAS DAIMTRCLA++
Sbjct 5690 YACWKHCLGFDFVYNPLLVDIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAIN 5749
Query 6209 ECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQ 6268
F + V+W + YP I +E ++N++CR +Q M + A + A K V++DIGNPK IKCV +
Sbjct 5750 NAFCQDVNWDLTYPHIANEDEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRR 5809
Query 6269 ADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDT 6328
DV ++FYD P + E Y Y H DKF DG+C+FWNCNVD YP NS+VCR+DT
Sbjct 5810 GDVNFRFYDKNPIVRNVKQFE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDT 5866
Query 6329 RVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDI 6388
R LS NLPGC+GGSLYVNKHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+
Sbjct 5867 RNLSVFNLPGCNGGSLYVNKHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ- 5925
Query 6389 DYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF 6448
D V L + CIT+CN+GGAVC+ HA Y ++ +YN ++AGF+ WV + + YNLW +F
Sbjct 5926 DLVSLATKDCITKCNIGGAVCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSF 5985
Query 6449 TRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFE 6508
+ LQS++N+A+N+ GH+D GE+P I + V+ GV+ +F N+TTLP +VAFE
Sbjct 5986 SALQSIDNIAYNMYKGGHYDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFE 6045
Query 6509 LWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETIC 6568
L+AKRNI+ +P +IL LGVD+ VIWDY P + +T+ VC+ TDI
Sbjct 6046 LYAKRNIRTLPNNRILKGLGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEPN------ 6099
Query 6569 APLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQ 6627
L V +D R G F A N VL++ K P + NG+ L A
Sbjct 6100 -GLVVLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---N 6154
Query 6628 FNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHI 6687
YK+V+G LP T TQ R+ + F+PRS +E DFL ++ + F+ERY + +HI
Sbjct 6155 LYVYKRVNGAFVTLPNTINTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHI 6213
Query 6688 VYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVI 6747
+YG+ QLGGLH +IG+ + + + + DS V + + GS K VC+V+
Sbjct 6214 LYGEVDKPQLGGLHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVLSDNGSYKQVCTVV 6273
Query 6748 DLLLDDFV----EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAW 6803
DLLLDDF+ I+K + SKVV V+IDY I+FM W +DG ++T YP+LQS+ W
Sbjct 6274 DLLLDDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQSA--W 6330
Query 6804 QPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNM 6863
G MP LYK+Q ++E C++ NYG TLP GI+MNVAKYTQLCQYL T+ VP+NM
Sbjct 6331 TCGYNMPELYKVQNCVMEPCNIPNYGVGITLPSGILMNVAKYTQLCQYLLKTTICVPHNM 6390
Query 6864 RVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWD 6923
RV+HFGAGSDKGVAPG+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC +T +K+D
Sbjct 6391 RVMHFGAGSDKGVAPGSTVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYNTEHKFD 6450
Query 6924 LIISDMY---DPKTKNVT-KENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLY 6979
L+ISDMY D K K+ N+ + F Y+ F++ LALGGS A+K+TE SW+ LY
Sbjct 6451 LVISDMYTDNDSKRKHEGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSWHEVLY 6510
Query 6980 KLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKP-REQIDGYVMHANYIFWRNTNPIQLS 7038
+ AWWT F T VNASSSEAFLIG NYLG + ++ G +HANYIFWRN N +Q S
Sbjct 6511 DIAQDCAWWTMFCTAVNASSSEAFLIGVNYLGASEKVKVSGKTLHANYIFWRNCNYLQTS 6570
Query 7039 SYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLV 7094
+YS+FD++KF L+L+ T V++LK Q D++ +L+ G+L++R+ +SD V
Sbjct 6571 AYSIFDVAKFDLRLKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 6626
Score = 145 bits (367), Expect = 1e-32, Method: Composition-based stats.
Identities = 69/328 (21%), Positives = 119/328 (36%), Gaps = 29/328 (9%)
Query 925 YPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWL--DD 982
P + E+ Q E D A + EE +E L
Sbjct 909 EPVENSTGSSKTMTEQVVVEDQELPVVEQDQDVVVYTPTDLEVAKETAEEVDEFILIFAV 968
Query 983 DSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPV---VQTIEVNSFSGYLKLTDNVY 1039
++ V Q+DG++ Q + I V+PQ E + T E F Y ++
Sbjct 969 PKEEVVSQKDGAQIKQ----EPIQVVKPQREKKAKKFKVKPATCEKPKFLEYKTCVGDLT 1024
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKV 1099
+ A ++E K+ +VNAAN ++ HG GVA A+ +DY+ +GP +
Sbjct 1025 VVIAKALDEFKEF---CIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ- 1080
Query 1100 GGSCVLSGHNLAKHCL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGA 1156
V C+ +VVGP + L +AY+N V+ + P+LS GIFG
Sbjct 1081 --RLVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGV 1138
Query 1157 D---PIHSLRVCVDTVRTNVYLAVFDKNLYDKL------VSSFL--EMKSEKQVEQKIAE 1205
D I ++R + V L + D + +L + + + K +
Sbjct 1139 DFKMSIDAMREAFEGCTIRVLLFSLSQEHIDYFDVTCKQKTIYLTEDGVKYRSIVLKPGD 1198
Query 1206 IPKEEVKPFITESKPSVEQRKQDDKKIK 1233
+ + + +D + +
Sbjct 1199 SLGQFGQVYAKNKIVFTADDVEDKEILY 1226
Score = 45.1 bits (105), Expect = 0.036, Method: Composition-based stats.
Identities = 50/374 (13%), Positives = 111/374 (30%), Gaps = 20/374 (5%)
Query 524 GEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA 583
G I L A ++ V + + + + L + D ++L
Sbjct 374 GVTPEINDGLILAAIYSSFSVSELVTALKK--GEPFKFLGHKFVYAKDAAVSFTLAKAAT 431
Query 584 MMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLR 643
+ L + V+ + + + ++ +G V + V ++ + V
Sbjct 432 IADVLRLFQSARVIAEDVWSSFTEKSFEFWKLAYGKVRNLEEFVKTYVCKAQMSIVILAA 491
Query 644 DGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII-IGGAKLKA 702
E + + + +G + + F + + + ++ + G
Sbjct 492 VLGEDIWHLVSQVIYKLGVLFTKVVDFCDKHWKGFCVQLKRAKLIVTETFCVLKGVAQHC 551
Query 703 LNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGD 762
L + ++KC R LL +I+ +G+ + + + V G
Sbjct 552 FQLLLDAIHSLYKSFKKCALGRIHGDLLFWKGGVHKIVQ-DGDEIWFDAIDSVDVEDLGV 610
Query 763 LQPLEQPTSEAVEAPLV----GTPVCING-----LMLLEIKDTEKYCALAPNMMVTNNTF 813
+Q + L G V I + KD Y + N
Sbjct 611 VQEKSIDFEVCDDVTLPENQPGHMVQIEDDGKNYMFFRFKKDENIYYTPMSQLGAINVVC 670
Query 814 TLKGGAPTKVTFGDDTVIEV--QGYKSVNITFELD-ERIDKVLNEKCS-AYTVELGTEVN 869
VTFG+ TV E+ + ++ E E + + + V+ V
Sbjct 671 K---AGGKTVTFGETTVQEIPPPDVVPIKVSIECCGEPWNTIFKKAYKEPIEVDTDLTVE 727
Query 870 EFACVVADAVIKTL 883
+ V+ + + L
Sbjct 728 QLLSVIYEKMCDDL 741
>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631
Score = 6673 bits (17312), Expect = 0.0, Method: Composition-based stats.
Identities = 2361/5696 (41%), Positives = 3285/5696 (58%), Gaps = 376/5696 (7%)
Query 1549 EVITFDNLKTLLSLREV--RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTK 1606
V+ F + + + + ++ T D + + V+ + G QFG + V
Sbjct 1159 RVLLFSLSQEHIDYFDATCKQKTIYLTEDGVKYRSVVLKPGDSLG-QFGQVFARNKVV-- 1215
Query 1607 IKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTS 1666
+ E K +P D +E Y+ D Y+ L +KW +
Sbjct 1216 -FSADDVEDKEILFIPTTDKTILE----YYGLDAQKYVTYLQTL--AQKWDVQYRDNFVI 1268
Query 1667 IKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELG 1726
++W D NC++++A++ LQ +++F L +A+ + G+ +F A A CN VG+
Sbjct 1269 LEWRDGNCWISSAIVLLQAAKIRFK-GFLAEAWAKLLGGDPTDFVAWCYASCNAKVGDFS 1327
Query 1727 DVRETMSYLFQHANLDSCKRVLN-VVCKTCGQQQTTLKGVEAVM-YMGTLSYEQFKKGVQ 1784
D ++ L +H + D +L V CG + L+G+EA + + + FK
Sbjct 1328 DANWLLANLAEHFDADYTNALLKKCVSCNCGVKSYELRGLEACIQPVRAPNLLHFKTQYS 1387
Query 1785 IPCTCGKQATKYLVQQESPFVMMSAPPAQYELK-HGTFTCASEYTGNYQCGH-YKHITSK 1842
TCG +T +++ P++++ A + + G+ GH Y K
Sbjct 1388 NCPTCGASSTDEVIEASLPYLLLFATDGPATVDCDENAVGTVVFIGSTNSGHCYTQADGK 1447
Query 1843 ETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKK 1902
D + K P Y S + + + + + N
Sbjct 1448 A----FDNLAKDRKFGRKSPYITAMYTRFSLRSENPLLVVEHSKGKAKVVKEDVSNL--- 1500
Query 1903 DNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPD 1962
ASFD+ D Q Y LKV PD
Sbjct 1501 ---------------ATSSKASFDDL----------TDFEQW--YDSNIYESLKVQETPD 1533
Query 1963 LNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETS 2022
+ Y T + + P T +R + S +
Sbjct 1534 --------NLDEYVS------------------FTTKEDSKLPLTLKVRGIKSVVDFRSK 1567
Query 2023 NSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVK---------TTEVVG 2073
+ F + D PV V+++ +++ +E + + +
Sbjct 1568 DGFTYKLTPDTD------ENSKTPVYYPVLDSISLRAIWVEGSANFVVGHPNYYSKSLRI 1621
Query 2074 DIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSV 2133
+ A + +K+ ++ + ++ + KPN L R+ + A G + V +
Sbjct 1622 PTFWENAESFVKMGYKIDGVTMGLWRAEH----LNKPN-LERIFNIAKKAIVGSSVVTTQ 1676
Query 2134 PWDTIANYAKPFLNKVVSTTTNIVTRCLNRVC---------TNYMPYFFTLLLQLCTFTR 2184
+ A +KV +T + +C + + TL+ F +
Sbjct 1677 CGKILVKAATYVADKVGDGVVRNITDRIKGLCGFTRGHFEKKMSLQFLKTLVFFFFYFLK 1736
Query 2185 STNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLI 2244
+++ + +S + K ++ +I+WF+ S ++
Sbjct 1737 ASSKSLVSSYKIVLCKVVFATL----------------------LIVWFIYTS---NPVV 1771
Query 2245 YSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSL 2304
++ + + L S C Y + +S + YC G C VCL DSL Y
Sbjct 1772 FTGIRV---LDFLFEGSLCGPYNDYGKDS--FDVLRYCAGDFTCRVCLHDRDSLHLYKHA 1826
Query 2305 ETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAIMQLFFSYFAVHFISNS 2362
+++ A G+ W Y++F F V G I Y + + +S
Sbjct 1827 YSVEQIYKD-----AASGINFNWNWLYLVFLILFVKPVAGFVII-----CYCVKYLVLSS 1876
Query 2363 WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVVDGCNSSTCMMCYKRNR 2417
++ + + + + + F + +Y W Y VH + C TC +C + R
Sbjct 1877 TVLQTGVGFLDWF-VKTVFTHFNFMGAGFYFWLFYKIYVQVHHILYCKDVTCEVCKRVAR 1935
Query 2418 ATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQF 2477
+ R E + +V G ++ +VY N G FCK HNW C NCD + +TF+S EVA +LS +
Sbjct 1936 SNRQEVSVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKL 1995
Query 2478 KRPINPTDQSSYIVDSVTVKNGSIHLYFDKA-GQKTYERHSLSHFVNLDNLR-ANNTKGS 2535
KR + PT + ++V V + ++L + A K ++ F D L+ A K +
Sbjct 1996 KRHVKPTAYAYHVVYEACVVDDFVNLKYKAAIPGKDNASSAVKCFSVTDFLKKAVFLKEA 2055
Query 2536 LPINVIVFDGKSKCEESSA------KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVK 2589
L I DG C SA K+A+VYY+Q +C+PIL+LDQAL +
Sbjct 2056 LKCEQISNDGFIVCNTQSAHALEEAKNAAVYYAQYLCKPILILDQALYEQL--------- 2106
Query 2590 MFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETK 2649
+ K+++ + L+ +S+D + + + + S + +
Sbjct 2107 --------------IVEPVSKSVIDKVCSILSNIISVDTAALNYKAGTLRDALLSITKDE 2152
Query 2650 DVVECLKLSHQSDIEVTGDSCNNYMLTYN-KVENMTPRDLGACIDCSARHINAQVAKSHN 2708
+ V+ H ++E TGD N + +Y + +TPRD G I+ A N +V +
Sbjct 2153 EAVDMAIFCHNHEVEYTGDGFTNVIPSYGMDTDKLTPRDRGFLINADASIANLRVKNAP- 2211
Query 2709 IALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL--KGGKIV 2766
++W D + LS+ K + SA K+ F +T + +QV++ T K+ + K G ++
Sbjct 2212 -PVVWKFSDLIKLSDSCLKYLISATVKSGGRFFITKSGAKQVISCHTQKLLVEKKAGGVI 2270
Query 2767 NN---WLKQLIKVTLVFLF-----VAAIFYLITPVHVMSKHTDFSS--EIIGYKAIDGGV 2816
NN W K VF +Y+ + D +S + G+K ID GV
Sbjct 2271 NNTFKWFMSCFKWLFVFYILFTACCLGYYYMEMNKSFVHPMYDVNSTLHVEGFKVIDKGV 2330
Query 2817 TRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRT 2876
R+I S D CF+NK +FD ++ G SY N+K CP++ VI + G V G+PG +
Sbjct 2331 IREIVSEDNCFSNKFVNFDAFW---GKSYENNKNCPIVTVVIDGD-GTVAVGVPGFVSWV 2386
Query 2877 TNG-DFLH---------FLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDAS 2926
+G F+H ++P F+ + YT +I F TS + +A C ++ AS
Sbjct 2387 MDGVMFVHMTQTDRRPWYIPTWFNRE-IVGYTQDSIITEGSFYTSIALFSARC-LYLTAS 2444
Query 2927 GKPVPYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCR 2985
P YC++ N G++ + S+ P Y +G + P L V DS YCR
Sbjct 2445 NTPQLYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQILHTPYIVKFVSDS-YCR 2503
Query 2986 HGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISA 3045
CE ++ G CVS +WVL ND Y S PGVFCG L+ NM + + +I
Sbjct 2504 GSVCEYTKPGYCVSLDSQWVLFNDEYISKPGVFCGSTVRELMFNMVSTFFTGVNP-NIYI 2562
Query 3046 SIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVY 3105
+ ++ +V+ + ++F+ F Y+ +V L+++++ VLC+ S L +
Sbjct 2563 QLATMFLILVVIVLIFAMVIKFQGVFKAYATIVFTIMLVWVINAFVLCVHSYNSVLAVIL 2622
Query 3106 SVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAY---IICISTKHFYWFFSNYLK 3162
V+Y Y + + + + + H + F +VP W+ Y I+ + T +W +
Sbjct 2623 LVLYCYASMVTSRNTAIIMHCWLVFTFGLIVPTWLACCYLGFILYMYTPLVFWCYGTTKN 2682
Query 3163 RRVVFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAM 3221
R +++G F ++ AA TF++ ++KL +++ ++ YL+ Y + KY+SG
Sbjct 2683 TRKLYDGNEFVGNYDLAAKSTFVIRGTEFVKLTNEIG---DKFEAYLSAYARLKYYSGTG 2739
Query 3222 DTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMV 3281
Y +A LA AL+ + NSG +V+Y PP+ SI + LQ+GF+K+ PS VE C+V
Sbjct 2740 SEQDYLQACRAWLAYALDQYRNSGVEVVYTPPRYSIGVSRLQAGFKKLVSPSSAVEKCIV 2799
Query 3282 QVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGN-VQLRV 3340
V+ LNGLWL D +YCPRHV+ + D+L +NH F V N V L V
Sbjct 2800 SVSYRGNNLNGLWLGDSIYCPRHVL---GKFSGDQWGDVLNLANNHEFEVVTQNGVTLNV 2856
Query 3341 IGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIK 3400
+ ++ VL L+ AN +TPKYKFV+ G +F++ Y G+ G+Y MR N TI+
Sbjct 2857 VSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIR 2916
Query 3401 GSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTD 3460
SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G FYG +VD + AQ D
Sbjct 2917 ASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPD 2976
Query 3461 TTITVNVLAWLYAAVIN-------GDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDIL 3513
+T N++AWLYAA+I+ +W L T ++ D+N A + P + +
Sbjct 2977 NLVTNNIVAWLYAAIISVKESSFSQPKW-LESTTVSIEDYNRWASDNGFTPFSTST--AI 3033
Query 3514 GPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVK 3573
LSA TG+ V + ++ + ILG EDE TP V Q GV QS+
Sbjct 3034 TKLSAITGVDVCKLLRTIM-VKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQSSFV 3092
Query 3574 RTIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 3630
R + W +L L L +V T L F+++ L A+ I+ + VK
Sbjct 3093 RKAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVHAAVILLMAVLFISFT------VK 3145
Query 3631 HKHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRIMTWLDM--VDTSL------- 3674
H A++ FLLP+L TV A +Y + + V+ + W D DT +
Sbjct 3146 HVMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMLLPL 3205
Query 3675 ---SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQA 3730
+ FK ++ C M + LL+L ++T N LT + GN
Sbjct 3206 VLYTAFKCVQGCYMNSFNTSLLMLYQFM----KLGFVIYTSSNTLTAYTE---GN----- 3253
Query 3731 ISMWALIISVTSNYSGVVTTVMFLARGIVFMC----VEYCPIFFITGNTLQCIMLVYCFL 3786
W L + + L IVF C + YC + L +M+ +
Sbjct 3254 ---WELFFELVHTIVLANVSSNSLIGLIVFKCAKWMLYYCNATYFNNYVLMAVMVN--GI 3308
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G
Sbjct 3309 GWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKVNPPKTVWEVFTTNILIQG 3368
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG + +ATVQSK+SDVKCT+VVL+ +L +L VE++SK+ A V+LHN IL + D E
Sbjct 3369 IGGDRVLPIATVQSKLSDVKCTTVVLMQLLTKLNVEANSKMHAYLVELHNKILASDDVGE 3428
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
+ ++ +L L + +D+ + C+++L LQ++ EFS +PSYA + A+ YE+
Sbjct 3429 CMDNLLGMLITLFCIDSTIDLGEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKSIYEK 3488
Query 3967 AVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKR 4022
+A+ G ++ L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+R
Sbjct 3489 VLADSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRR 3548
Query 4023 AKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKN 4082
AK+ S++ +LF+ML+K+D++ LN + + A G VPL +P+ + KL +VIPD T+
Sbjct 3549 AKLVSSLHALLFSMLKKIDSEKLNVLFDQANSGVVPLATVPIVCSNKLTLVIPDPETWVK 3608
Query 4083 TCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-----NSPNLAWPLIVTALRANSA- 4136
+G TY++ +W I V DAD + + + N+AWPL V R
Sbjct 3609 CVEGVHVTYSTVVWNIDCVTDADGTELHPTSTGSGLTYCISGDNIAWPLKVNLTRNGHNK 3668
Query 4137 --VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
V LQNNEL P ++ +C AG Q C+ ++ YY + G V A+ S +LK A
Sbjct 3669 VDVALQNNELMPHGVKTKACVAGVDQAHCSVES-KCYYTSISGSSVVAAITSSNPNLKVA 3727
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
F G IY +L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+
Sbjct 3728 SFLNEAGN-QIYVDLDPPCKFGMKVGDKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQS 3786
Query 4255 -GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
G+ TE +LS C+FAVD A Y Y+A+G QP+ NCVKML H G+G AIT P
Sbjct 3787 KGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPS 3846
Query 4314 ANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
DQ+S+GGAS CLYCR HI HP N G C KG +VQIPTT DPVGF L+N V
Sbjct 3847 PTPDQDSYGGASVCLYCRAHIAHPGGAGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKV 3905
Query 4370 CTVCGMWKGYGCSCDQLREP-------MLQSADAQSFLNRVCGVSAARLTPCGTGTSTDV 4422
CTVC W GYGC CD LR+P + S +++LNRV G S ARL P G DV
Sbjct 3906 CTVCQCWIGYGCQCDSLRQPKPSVQSVAVASGFDKNYLNRVRGSSEARLIPLANGCDPDV 3965
Query 4423 VYRAFDIYNDKVAGFAKFLKTNCCRFQEK--DEDDNL--IDSYFVVKRHTFSNYQHEETI 4478
V RAFD+ N + AG + LK NC RFQE ED NL DSYFVVK+ T SNY+HE+
Sbjct 3966 VKRAFDVCNKESAGMFQNLKRNCARFQEVRDTEDGNLEYCDSYFVVKQTTPSNYEHEKAC 4025
Query 4479 YNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEIL 4538
Y LK A HDFF F + + +ISRQRLTKYTM D YALRHFD +C+ LKEIL
Sbjct 4026 YEDLKS-EVTADHDFFVFNKN---IYNISRQRLTKYTMMDFCYALRHFDPKDCEVLKEIL 4081
Query 4539 VTYNCCDD---DYFN-KKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIV 4594
VTY C +D +F KDWYD +ENP + A +G VR+ALL ++F + M G V
Sbjct 4082 VTYGCIEDYHPKWFEENKDWYDPIENPKYYAMLAKMGPIVRRALLNAIEFGNLMVEKGYV 4141
Query 4595 GVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLT 4654
GV+TLDNQDLNG +YDFGDF +T PG+GVPV D+YYS +MPI+ +T AL E + + D+
Sbjct 4142 GVITLDNQDLNGKFYDFGDFQKTAPGAGVPVFDTYYSYMMPIIAMTDALAPERYFEYDVH 4201
Query 4655 KPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFP 4714
K Y +DLLKYD+TEE+ LF +YFKYWDQ YHPNC +C DDRC++HCANFN+LFST+ P
Sbjct 4202 KGYKSYDLLKYDYTEEKQDLFQKYFKYWDQEYHPNCRDCSDDRCLIHCANFNILFSTLVP 4261
Query 4715 PTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHA 4774
TSFG L RK+FVDGVPF+ + GYH +ELGV+ NQD + S++ +L+ + DPA+
Sbjct 4262 QTSFGNLCRKVFVDGVPFIATCGYHSKELGVIMNQDNTMSFSKMGLSQLMQFVGDPALLV 4321
Query 4775 ASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFF 4834
+ N L+D RT+CFSV AL + + QTVKPG+FNKDFYDFA G FKEGSS+ LKHFF+
Sbjct 4322 GTSNKLVDLRTSCFSVCALASGITHQTVKPGHFNKDFYDFAEKAGMFKEGSSIPLKHFFY 4381
Query 4835 AQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSA 4894
Q GNAAI+DYDYYRYN PTM DIRQLLF +EV KYF+CY+GGCI A+QV+VNNLDKSA
Sbjct 4382 PQTGNAAINDYDYYRYNRPTMFDIRQLLFCLEVTSKYFECYEGGCIPASQVVVNNLDKSA 4441
Query 4895 GFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSI 4954
G+PFNK+GKARLYY+ MS E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI
Sbjct 4442 GYPFNKFGKARLYYE-MSLEEQDQLFESTKKNVLPTITQMNLKYAISAKNRARTVAGVSI 4500
Query 4955 CSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKC 5014
STMTNRQFHQK+LKSI TR A VVIGT+KFYGGW NML+ + VE+P LMGWDYPKC
Sbjct 4501 LSTMTNRQFHQKILKSIVNTRNAPVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKC 4560
Query 5015 DRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSS 5074
DRAMPN+LRI ASLVLARKHT CC+ S R YRL NECAQVLSE V+ G +YVKPGGTSS
Sbjct 4561 DRAMPNLLRIAASLVLARKHTNCCTWSERVYRLYNECAQVLSETVLATGGIYVKPGGTSS 4620
Query 5075 GDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFV 5134
GDATTAYANSVFNI QA +ANV LLS I +++LQ+ LY+ +YR + D FV
Sbjct 4621 GDATTAYANSVFNIIQATSANVARLLSVITRDIVYDDIKSLQYELYQQVYRRVNFDPAFV 4680
Query 5135 NEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTE 5194
+FY+YL K+FS+MILSDD VVC+N+T A QGLVA I F+ VLYYQNNVFM+++KCW E
Sbjct 4681 EKFYSYLCKNFSLMILSDDGVVCYNNTLAKQGLVADISGFREVLYYQNNVFMADSKCWVE 4740
Query 5195 TDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSL 5254
DL KGPHEFCSQHTMLV+ + YLPYPDPSRIL A FVDD+ KT+ ++ER+++L
Sbjct 4741 PDLEKGPHEFCSQHTMLVEVDGEPRYLPYPDPSRILCACVFVDDLDKTESVAVMERYIAL 4800
Query 5255 AIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYE 5314
AIDAYPL H N+EY VF + L YIRKL+ EL+ +ML YS ++ D S++WE EFYE
Sbjct 4801 AIDAYPLVHHENEEYKKVFFVLLSYIRKLYQELSQNMLMDYSFVMDIDKGSKFWEQEFYE 4860
Query 5315 AMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVC 5374
MY T LQ+ G CV+CNSQT LRCG CIR+PFLCCKCCYDHV+ T HK VLS+NPY+C
Sbjct 4861 NMYRAPTTLQSCGVCVVCNSQTILRCGNCIRKPFLCCKCCYDHVMHTDHKNVLSINPYIC 4920
Query 5375 NAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIA 5434
+ PGC DVT+LYLGGMSY+C +HKP +S PL +NG VFG+Y+ C GS+NV DFN +A
Sbjct 4921 SQPGCGEADVTKLYLGGMSYFCGNHKPKLSIPLVSNGTVFGIYRANCAGSENVDDFNQLA 4980
Query 5435 TCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVG 5494
T +W+ YILAN C + L+ FAAET+KATEE K + A VREVLSDREL LSWE G
Sbjct 4981 TTNWSTVEPYILANRCVDSLRRFAAETVKATEELHKQQFASAEVREVLSDRELILSWEPG 5040
Query 5495 KPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSH 5554
K RPPLNRNYVFTG+ T+ SKVQ+G++TFEKG+ D V YR T+T KL+VGD FVLTSH
Sbjct 5041 KTRPPLNRNYVFTGFHFTRTSKVQLGDFTFEKGEGKDVVYYRATSTAKLSVGDIFVLTSH 5100
Query 5555 TVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSH 5614
V+ L APTL PQ+ + R L P + + F +N+ Y VG QK +T+QGPPG+GKSH
Sbjct 5101 NVVSLIAPTLCPQQTFSRFVNLRPNVMVPACFVNNIPLYHLVGKQKRTTVQGPPGSGKSH 5160
Query 5615 FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNS 5674
FAIGLA Y+ +AR+V+TACSHAAVDALCEKA K+L +D C+RI+P R ++CF KFK N
Sbjct 5161 FAIGLAAYFSNARVVFTACSHAAVDALCEKAFKFLKVDDCTRIVPQRTTIDCFSKFKAND 5220
Query 5675 TLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRT 5734
T ++Y+F T+NALPE + DI++ DE+SM TNY+LS +N ++ ++ VY+GDPAQLPAPRT
Sbjct 5221 TGKKYIFSTINALPEVSCDILLVDEVSMLTNYELSFINGKINYQYVVYVGDPAQLPAPRT 5280
Query 5735 LLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ 5794
LL G+L P+ +N V LM + PD+FL C RCP EIVDTVS LVYD K A+ +S Q
Sbjct 5281 LLN-GSLSPKDYNVVTNLMVCVKPDIFLAKCYRCPKEIVDTVSTLVYDGKFIANNPESRQ 5339
Query 5795 CFKMFYKG---VITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILG 5851
CFK+ + H+ SA N Q+ V++F+ RN WR+A FISPYN+ N A ++LG
Sbjct 5340 CFKVIVNNGNSDVGHESGSAYNITQLEFVKDFVCRNKEWREATFISPYNAMNQRAYRMLG 5399
Query 5852 LPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRD-LYDKLQ 5910
L QTVDSSQGSEYDYVIF T ++ H+ N+NRFNVA+TRAK GIL +M RD LY L+
Sbjct 5400 LNVQTVDSSQGSEYDYVIFCVTADSQHALNINRFNVALTRAKRGILVVMRQRDELYSALK 5459
Query 5911 FTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGI 5970
F L+ +VA+LQ TGLFK C+K +G+HP A T ++ +K + +
Sbjct 5460 FIELD----SVASLQG---TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNV 5512
Query 5971 P--KDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGT 6028
++TY+ LIS++GFKM+ V G NMFITR+EAIR+VR W+GFDVE HA +GT
Sbjct 5513 EAGSEITYKHLISLLGFKMSVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGT 5572
Query 6029 NLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVR 6088
NLP Q+GFSTG + V P G VDT +F V++K PPG+QF HL L PW+VVR
Sbjct 5573 NLPFQVGFSTGADFVVTPEGLVDTSIGNNFEPVNSKAPPGEQFNHLRALFKSAKPWHVVR 5632
Query 6089 IKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDT 6148
+IVQML+D L N+SD VVFV W HG ELT+++YFVKIG ++ C C RAT F++ +
Sbjct 5633 PRIVQMLADNLCNVSDCVVFVTWCHGLELTTLRYFVKIGKDQVCS-CGSRATTFNSHTQA 5691
Query 6149 YACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVH 6208
YACW H +GFD+VYNP ++D+QQWG++GNLQ NHDL+C VHG+AHVAS DAIMTRCLA++
Sbjct 5692 YACWKHCLGFDFVYNPLLVDIQQWGYSGNLQFNHDLHCNVHGHAHVASADAIMTRCLAIN 5751
Query 6209 ECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQ 6268
F + V+W + YP I +E ++N++CR +Q M + A + A K V++DIGNPK IKCV +
Sbjct 5752 NAFCQDVNWDLTYPHIANEDEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRR 5811
Query 6269 ADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDT 6328
D+ ++FYD P + E Y Y H DKF DG+C+FWNCNVD YP NS+VCR+DT
Sbjct 5812 GDLNFRFYDKNPIVPNVKQFE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDT 5868
Query 6329 RVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDI 6388
R LS NLPGC+GGSLYVNKHAFHTP FD+++F NLK +PFF+Y SPCE+ V+
Sbjct 5869 RNLSVFNLPGCNGGSLYVNKHAFHTPKFDRTSFRNLKAMPFFFYDSSPCETIQLDGVAQ- 5927
Query 6389 DYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF 6448
D V L + CIT+CN+GGAVC+ HA Y ++ +YN ++AGF+ WV F+ YNLW +F
Sbjct 5928 DLVSLATKDCITKCNIGGAVCKKHAQMYADFVTSYNAAVTAGFTFWVTNNFNPYNLWKSF 5987
Query 6449 TRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFE 6508
+ LQS++N+A+N+ GH+D GE+P + + V+ GV+ +F N+T LP +VAFE
Sbjct 5988 SALQSIDNIAYNMYKGGHYDAIAGEMPTIVTGDKVFVIDQGVEKAVFFNQTILPTSVAFE 6047
Query 6509 LWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETIC 6568
L+AKRNI+ +P +IL LGVD+ VIWDY P + +T+ VC+ TDI
Sbjct 6048 LYAKRNIRTLPNNRILKGLGVDVTNGFVIWDYTNQTPLYRNTVKVCAYTDIEPN------ 6101
Query 6569 APLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQ 6627
L V +D R G F A N VL++ K P + NG+ L A
Sbjct 6102 -GLIVLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGIPLKDGA---N 6156
Query 6628 FNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHI 6687
YK+V+G LP T TQ R+ + F+PRS +E DFL+++ + F+E+Y E +HI
Sbjct 6157 LYVYKRVNGAFVTLPNTLNTQGRSYETFEPRSDVERDFLDMSEESFVEKYGKE-LGLQHI 6215
Query 6688 VYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVI 6747
+YG+ QLGGLH +IG+ + + + + DS V + A GS K VC+V+
Sbjct 6216 LYGEVDKPQLGGLHTVIGMCRLLRANKLNAKSVTNSDSDVMQNYFVLADNGSYKQVCTVV 6275
Query 6748 DLLLDDFV----EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAW 6803
DLLLDDF+ I+K + SKVV V+IDY I+FM W +DG ++T YP+LQS+ W
Sbjct 6276 DLLLDDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFMAWFEDGIIKTCYPQLQSA--W 6332
Query 6804 QPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNM 6863
G MP LYK+Q ++E C++ NYG LP GIMMNVAKYTQLCQYL+ T+ VP+NM
Sbjct 6333 TCGYNMPELYKVQNCVMEPCNIPNYGVGIALPSGIMMNVAKYTQLCQYLSKTTMCVPHNM 6392
Query 6864 RVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWD 6923
RV+HFGAGSDKGVAPG+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC T +K+D
Sbjct 6393 RVMHFGAGSDKGVAPGSTVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYKTEHKFD 6452
Query 6924 LIISDMY---DPKTKNVT-KENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLY 6979
L+ISDMY D K K+ N+ + F Y+ F++ LALGGS A+K+TE SW+ LY
Sbjct 6453 LVISDMYTDNDSKRKHEGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSWHEVLY 6512
Query 6980 KLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKP-REQIDGYVMHANYIFWRNTNPIQLS 7038
+ AWWT F T VNASSSEAFL+G NYLG + ++ G +HANYIFWRN N +Q S
Sbjct 6513 DIAQDCAWWTMFCTAVNASSSEAFLVGVNYLGASEKVKVSGKTLHANYIFWRNCNYLQTS 6572
Query 7039 SYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLV 7094
+YS+FD++KF L+L+ T V++LK Q D++ +L+ G+L++R+ +SD V
Sbjct 6573 AYSIFDVAKFDLRLKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 6628
Score = 147 bits (370), Expect = 6e-33, Method: Composition-based stats.
Identities = 60/315 (19%), Positives = 112/315 (36%), Gaps = 23/315 (7%)
Query 933 EGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQD 992
D E+ Q + Q + A ++ E+ ++++ +
Sbjct 917 SCDAMAEQAIVEEQEIVPVVEQSQDVVVFTPADLEVVKETAEEVDEFILISAVPKEEVVS 976
Query 993 GSEDNQTTTIQTIVEVQPQLEMELTPV---VQTIEVNSFSGYLKLTDNVYIKNADIVEEA 1049
++ + + V+ Q E + T E F Y ++ + A ++E
Sbjct 977 QEKEEPQVEQEPTLVVKAQREKKAKKFKVKPATCEKPKFLEYKTCVGDLAVVIAKALDEF 1036
Query 1050 KKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHN 1109
K+ +VNAAN ++ HGGGVA A+ DY+ +GP + V
Sbjct 1037 KEF---CIVNAANEHMSHGGGVAKAIADFCGPDFVEYCADYVKKHGPQQ---KLVTPSFV 1090
Query 1110 LAKHCL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGAD---PIHSLR 1163
C+ +VVGP + L +AY++ V+ + P+LS+GIFG D I ++R
Sbjct 1091 KGIQCVNNVVGPRHGDSNLREKLVAAYKSVLVGGVVNYVVPVLSSGIFGVDFKISIDAMR 1150
Query 1164 VCVDTVRTNVYLAVFDKNLYDKL------VSSFL--EMKSEKQVEQKIAEIPKEEVKPFI 1215
V L + D + +L + + V K + + + F
Sbjct 1151 EAFKGCAIRVLLFSLSQEHIDYFDATCKQKTIYLTEDGVKYRSVVLKPGDSLGQFGQVFA 1210
Query 1216 TESKPSVEQRKQDDK 1230
+D +
Sbjct 1211 RNKVVFSADDVEDKE 1225
Score = 51.2 bits (121), Expect = 5e-04, Method: Composition-based stats.
Identities = 57/375 (15%), Positives = 113/375 (30%), Gaps = 22/375 (6%)
Query 524 GEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA 583
G I L A ++ V + + + L + D ++L
Sbjct 374 GVTPEINDGLILAAIYSSFSVAELVAAIKR--GEPFKFLGHKFVYAKDAAVSFTLAKAAT 431
Query 584 MMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFK-EGVEFL 642
+ L + V + + + + + ++ +G V L+ + K + V
Sbjct 432 IADVLKLFQSARVKVEDVWSSLTEKSFEFWRLAYGKVRN-LEEFVKTCFCKAQMAIVILA 490
Query 643 RDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII-IGGAKLK 701
E + + + VGG ++ + F + + + +++ + G
Sbjct 491 TVLGEGIWHLVSQVIYKVGGLFTKVVDFCEKYWKGFCAQLKRAKLIVTETLCVLKGVAQH 550
Query 702 ALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTG 761
L + ++KC R LL +II EG+ + + + V G
Sbjct 551 CFQLLLDAIQFMYKSFKKCALGRIHGDLLFWKGGVHKIIQ-EGDEIWFDAIDSIDVEDLG 609
Query 762 DLQPLEQPTSEAVEAPLV----GTPVCING-----LMLLEIKDTEKYCALAPNMMVTNNT 812
+Q L G V I + KD Y + N
Sbjct 610 VVQEKLIDFDVCDNVTLPENQPGHMVQIEDDGKNYMFFRFKKDENIYYTPMSQLGAINVV 669
Query 813 FTLKGGAPTKVTFGDDTVIEV--QGYKSVNITFELD-ERIDKVLNEKCS-AYTVELGTEV 868
VTFG+ TV E+ + ++ E E + + + VE V
Sbjct 670 CK---AGGKTVTFGETTVQEIPPPDVVFIKVSIECCGEPWNTIFKKAYKEPIEVETDLTV 726
Query 869 NEFACVVADAVIKTL 883
+ VV + + L
Sbjct 727 EQLLSVVYEKMCDDL 741
>sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 PE=1 SV=1
Length=4405
Score = 5954 bits (15445), Expect = 0.0, Method: Composition-based stats.
Identities = 4401/4401 (100%), Positives = 4401/4401 (100%), Gaps = 0/4401 (0%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV
Sbjct 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK
Sbjct 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW
Sbjct 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI
Sbjct 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL
Sbjct 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC
Sbjct 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF
Sbjct 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA
Sbjct 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY
Sbjct 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV
Sbjct 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC
Sbjct 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG
Sbjct 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN 840
TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN
Sbjct 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVN 840
Query 841 ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW 900
ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW
Sbjct 841 ITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEW 900
Query 901 SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL 960
SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL
Sbjct 901 SMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPL 960
Query 961 EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV 1020
EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV
Sbjct 961 EFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVV 1020
Query 1021 QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN
Sbjct 1021 QTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
Query 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ 1140
NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ
Sbjct 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ 1140
Query 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE 1200
HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE
Sbjct 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE 1200
Query 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN 1260
QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN
Sbjct 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDIN 1260
Query 1261 GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV 1320
GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV
Sbjct 1261 GNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV 1320
Query 1321 PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA 1380
PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA
Sbjct 1321 PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLA 1380
Query 1381 HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND 1440
HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND
Sbjct 1381 HAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLND 1440
Query 1441 LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH 1500
LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH
Sbjct 1441 LNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEH 1500
Query 1501 FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL 1560
FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL
Sbjct 1501 FIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLL 1560
Query 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV
Sbjct 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
Query 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL
Sbjct 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
Query 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN
Sbjct 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
Query 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ
Sbjct 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
Query 1801 ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK 1860
ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK
Sbjct 1801 ESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYK 1860
Query 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY 1920
GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY
Sbjct 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPY 1920
Query 1921 PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK
Sbjct 1921 PNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
Query 1981 KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA 2040
KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA
Sbjct 1981 KGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLA 2040
Query 2041 CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV
Sbjct 2041 CEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYV 2100
Query 2101 DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC 2160
DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC
Sbjct 2101 DNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRC 2160
Query 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS
Sbjct 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
Query 2221 PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT 2280
PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT
Sbjct 2221 PNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIAT 2280
Query 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV
Sbjct 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
Query 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV
Sbjct 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA
Sbjct 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH
Sbjct 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV
Sbjct 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG
Sbjct 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
Query 2641 FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN 2700
FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN
Sbjct 2641 FVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHIN 2700
Query 2701 AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL 2760
AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL
Sbjct 2701 AQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL 2760
Query 2761 KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI 2820
KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI
Sbjct 2761 KGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDI 2820
Query 2821 ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD 2880
ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD
Sbjct 2821 ASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGD 2880
Query 2881 FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE 2940
FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE
Sbjct 2881 FLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLE 2940
Query 2941 GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST 3000
GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST
Sbjct 2941 GSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVST 3000
Query 3001 SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL
Sbjct 3001 SGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
Query 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV
Sbjct 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
Query 3121 SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL 3180
SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL
Sbjct 3121 SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAAL 3180
Query 3181 CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND 3240
CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND
Sbjct 3181 CTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALND 3240
Query 3241 FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY 3300
FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY
Sbjct 3241 FSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVY 3300
Query 3301 CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK 3360
CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK
Sbjct 3301 CPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPK 3360
Query 3361 TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV 3420
TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV
Sbjct 3361 TPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCV 3420
Query 3421 SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR 3480
SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR
Sbjct 3421 SFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDR 3480
Query 3481 WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN
Sbjct 3481 WFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
Query 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW
Sbjct 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
Query 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV
Sbjct 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
Query 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK
Sbjct 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
Query 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM
Sbjct 3721 VYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIM 3780
Query 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL
Sbjct 3781 LVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKL 3840
Query 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL
Sbjct 3841 NIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILL 3900
Query 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA
Sbjct 3901 AKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATA 3960
Query 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED
Sbjct 3961 QEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSED 4020
Query 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY
Sbjct 4021 KRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTY 4080
Query 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ 4140
KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ
Sbjct 4081 KNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQ 4140
Query 4141 NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD 4200
NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD
Sbjct 4141 NNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSD 4200
Query 4201 GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV 4260
GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV
Sbjct 4201 GTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEV 4260
Query 4261 PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES 4320
PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES
Sbjct 4261 PANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQES 4320
Query 4321 FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG 4380
FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG
Sbjct 4321 FGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYG 4380
Query 4381 CSCDQLREPMLQSADAQSFLN 4401
CSCDQLREPMLQSADAQSFLN
Sbjct 4381 CSCDQLREPMLQSADAQSFLN 4401
>sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respiratory
syndrome coronavirus OX=694009 GN=1a PE=1 SV=1
Length=4382
Score = 5939 bits (15407), Expect = 0.0, Method: Composition-based stats.
Identities = 3536/4408 (80%), Positives = 3933/4408 (89%), Gaps = 37/4408 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA + HGH +VELVAE++GIQYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGK+ CTLSEQLD+I++KRGVYCCR+HEHEIAW
Sbjct 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVASP ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + E+GPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+Q+S+L+PL F S+A
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIF+RTL+ A +S+ LQ+AA+TILDGIS+ SLRL+DAM++TSDL TN++++MAY
Sbjct 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ TSQWL+N+ GT EKL+P+ +W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVC+NGLMLLEIKD E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV EVQGYK+V
Sbjct 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ-YEYGTEDDYQGK 958
WS+AT+YLFD++GE +S MYCSFYPPDE+EE+ EEE T +EYGTEDDYQG
Sbjct 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
Query 959 PLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
PLEFGA++ ++ EEE+EEDWLDD ++Q+
Sbjct 961 PLEFGASAETVRVEEEEEEDWLDDTTEQSE------------------------IEPEPE 996
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
VN F+GYLKLTDNV IK DIV+EA+ P V+VNAAN++LKHGGGVAGALNKA
Sbjct 997 PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKA 1056
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
TN AMQ ESDDYI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYENF
Sbjct 1057 TNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENF 1116
Query 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
N ++LLAPLLSAGIFGA P+ SL+VCV TVRT VY+AV DK LY+++V +L+ +
Sbjct 1117 NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPR- 1175
Query 1199 VEQKIAEIPKEEVKPFI----TESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLL 1254
E PK+E P TE K V++ KIKAC++EVTTTLEETKFLT LL
Sbjct 1176 -----VEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLL 1230
Query 1255 LYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLA 1314
L+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML+
Sbjct 1231 LFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLS 1290
Query 1315 KALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWN 1374
+AL+KVP D YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSWN
Sbjct 1291 RALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWN 1350
Query 1375 LREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASL 1434
LREMLAHAEETRKLMP+C++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS+
Sbjct 1351 LREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASI 1410
Query 1435 INTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS 1494
I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSSS
Sbjct 1411 ITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSS 1470
Query 1495 KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVITF 1553
KT EEHF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGEV++
Sbjct 1471 KTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSL 1530
Query 1554 DNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSH 1613
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH +H
Sbjct 1531 DKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNH 1590
Query 1614 EGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNN 1673
EGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNN
Sbjct 1591 EGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN 1650
Query 1674 CYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMS 1733
CYL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM+
Sbjct 1651 CYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMT 1710
Query 1734 YLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQA 1793
+L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+ A
Sbjct 1711 HLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDA 1770
Query 1794 TKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALL 1853
T+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA L
Sbjct 1771 TQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHL 1830
Query 1854 TKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPID 1913
TK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPID
Sbjct 1831 TKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPID 1890
Query 1914 LVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYK 1973
LVP QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY+
Sbjct 1891 LVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYR 1950
Query 1974 HYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDA 2033
HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1951 HYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDT 2010
Query 2034 QGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHT 2093
QGMDNLACE +P SEEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+GH
Sbjct 2011 QGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHE 2070
Query 2094 DLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTT 2153
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + TT
Sbjct 2071 DLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITT 2130
Query 2154 TNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEA 2213
+N R RV NYMPY FTLL QLCTFT+STNSRI+AS+PTTIAKN+VKSV K CL+A
Sbjct 2131 SNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
Query 2214 SFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNS 2273
NY+KSP FSKL I +W LLLS+CLGSLI TAA GVL+SN G PSYC G RE YLNS
Sbjct 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNS 2250
Query 2274 TNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYIL 2333
+NVT +C GS PCS+CLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+L
Sbjct 2251 SNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYML 2310
Query 2334 FTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYV 2393
FT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY+
Sbjct 2311 FTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYI 2370
Query 2394 WKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCV 2453
WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC+
Sbjct 2371 WKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCL 2430
Query 2454 NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTY 2513
NCDTFC GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV VKNG++HLYFDKAGQKTY
Sbjct 2431 NCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTY 2490
Query 2514 ERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLD 2573
ERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES++KSASVYYSQLMCQPILLLD
Sbjct 2491 ERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLD 2550
Query 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
QALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF
Sbjct 2551 QALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTF 2610
Query 2634 ISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACID 2693
+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACID
Sbjct 2611 VSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACID 2670
Query 2694 CSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNV 2753
C+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV
Sbjct 2671 CNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNV 2730
Query 2754 VTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAID 2813
+TTKI+LKGGKIV+ K ++K TL+ + A + Y++ PVH +S H +++EIIGYKAI
Sbjct 2731 ITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQ 2790
Query 2814 GGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTI 2873
GVTRDI STD CFANKHA FD WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT+
Sbjct 2791 DGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTV 2850
Query 2874 LRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC 2933
LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYC
Sbjct 2851 LRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYC 2910
Query 2934 YDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
YDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2911 YDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE 2970
Query 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
G+C+STSGRWVLNN++YR+L GVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+
Sbjct 2971 VGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGII 3030
Query 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
AI+VTC AYYFM+FRR FGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYSV YLYLT
Sbjct 3031 AILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLT 3090
Query 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFS 3173
FY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNGV+FS
Sbjct 3091 FYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFS 3150
Query 3174 TFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCH 3233
TFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCH
Sbjct 3151 TFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCH 3210
Query 3234 LAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
LAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL
Sbjct 3211 LAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3270
Query 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
WLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LK
Sbjct 3271 WLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLK 3330
Query 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
VDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGF
Sbjct 3331 VDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGF 3390
Query 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
NIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYA
Sbjct 3391 NIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYA 3450
Query 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKE
Sbjct 3451 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
Query 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
LLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+
Sbjct 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLI 3570
Query 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMV
Sbjct 3571 LVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMV 3630
Query 3654 YMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMN 3713
YMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMN
Sbjct 3631 YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMN 3690
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITG
Sbjct 3691 VITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
NTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+
Sbjct 3751 NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKS 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ
Sbjct 3811 SIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPS 3953
LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPS
Sbjct 3871 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPS 3930
Query 3954 YAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 4013
YAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY
Sbjct 3931 YAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 3990
Query 4014 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4073
KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV
Sbjct 3991 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4050
Query 4074 IPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 4133
+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRA
Sbjct 4051 VPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRA 4110
Query 4134 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKW 4193
NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLKW
Sbjct 4111 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKW 4170
Query 4194 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4253
ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ
Sbjct 4171 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4230
Query 4254 AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
AGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE
Sbjct 4231 AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4290
Query 4314 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVC 4373
ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVC
Sbjct 4291 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 4350
Query 4374 GMWKGYGCSCDQLREPMLQSADAQSFLN 4401
GMWKGYGCSCDQLREP++QSADA +FLN
Sbjct 4351 GMWKGYGCSCDQLREPLMQSADASTFLN 4378
>sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus
HKU3 OX=442736 GN=1a PE=3 SV=1
Length=4376
Score = 5892 bits (15285), Expect = 0.0, Method: Composition-based stats.
Identities = 3532/4404 (80%), Positives = 3922/4404 (89%), Gaps = 35/4404 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA + HGH +VELVAEL+GIQ+GRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAELDGIQFGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHS+G DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
TRYVDNNFCGPDGYPLECIKD LARAGK+ CTLSEQLD+I++KRGVYCCREHEHEI W
Sbjct 181 VVTRYVDNNFCGPDGYPLECIKDFLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERSEKSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSEKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + EVGPEHS+A+YHN S ++T LRKGGRT FGGCVFSYVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFSYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIG NHTG+ GE E LN++LLEIL +E+VNINIVGDF+ NEE+AIILASF
Sbjct 421 AYWVPRASANIGANHTGITGENVETLNEDLLEILNRERVNINIVGDFRFNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SAS SAF+ETVKGLDYK+FK IVESCGN+KVT GK GAWNIG+Q+SIL+PL F S+A
Sbjct 481 SASPSAFIETVKGLDYKSFKVIVESCGNYKVTNGKPVTGAWNIGQQRSILTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIFSRTL+ A +S+ LQ+AA+T LDGIS+ SLRL+DAM++TSDL TN++VVMAY
Sbjct 541 AGVIRSIFSRTLDAANHSILDLQRAAVTTLDGISEQSLRLVDAMVYTSDLLTNSVVVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ T QWL+N+ GT +KLKPV W+E K GVEFLRD WEI+KF+ T +++
Sbjct 601 VTGGLVQQTMQWLSNMLGTAVDKLKPVFTWVEAKLSAGVEFLRDAWEILKFLITGVFDVI 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI IKE V+ F +VNK L +C D + I G KL+ALNLGE F+ S+GLYR+C
Sbjct 661 KGQIQVATDNIKECVKIFLGVVNKALEMCLDQVTIAGTKLRALNLGEVFIAQSRGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG+ T + +EEVVLK+G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDAHDTVLTSEEVVLKSGELEALETPIDSFTSGAVVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVCINGLMLLE+++ E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCINGLMLLELENKEQYCALSPGLLATNNVFRLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELD R+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLTP+GIDLDE
Sbjct 841 KITFELDVRVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTPMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKP 959
WS+AT+YLFD++GE KL+S MYCSFYPPD EEE E E+ E + ++EYGTEDDY+G P
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPD--EEEDCEECEDEEETCEHEYGTEDDYKGLP 958
Query 960 LEFGATSAALQPEEEQEE-DWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
LEFGA++ EEE+EE DWLDD + +
Sbjct 959 LEFGASTETPHVEEEEEEEDWLDDAIEAEPEPE--------------------------- 991
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
+ VN F GYLKLTDNV IK DIV+EA+ KPTV+VNAAN +LKHGGGVAGALNKA
Sbjct 992 PLPEEPVNQFVGYLKLTDNVAIKCIDIVKEAQSAKPTVIVNAANTHLKHGGGVAGALNKA 1051
Query 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
TN AMQ ESD+YI NGPL VGGSC+LSGHNLA+ CLHVVGPN+N GED+QLLK AYENF
Sbjct 1052 TNGAMQNESDEYIRQNGPLTVGGSCLLSGHNLAEKCLHVVGPNLNAGEDVQLLKRAYENF 1111
Query 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
N +VLLAPLLSAGIFGA P+ SL++CV+ VRT VYLAV DK+LYD++V +L+ K
Sbjct 1112 NSQDVLLAPLLSAGIFGAKPLQSLKMCVEIVRTQVYLAVNDKSLYDQIVLDYLDSLKPKV 1171
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYID 1258
E PK E + +P E+ KIKAC++EVTTTLEETKFLT LLL+ D
Sbjct 1172 ESPNKEEEPKLEEPKAV---QPVAEKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFAD 1228
Query 1259 INGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALR 1318
ING L+ DS ++ D++FL+KDAPYIVGDV+ G +T V+IP KK+GGTTEMLA+AL+
Sbjct 1229 INGKLYQDSQNMLRGEDMSFLEKDAPYIVGDVITSGDITCVIIPAKKSGGTTEMLARALK 1288
Query 1319 KVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREM 1378
+VP YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS NEK+E+LGTVSWNLREM
Sbjct 1289 EVPVAEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSETPNEKEEVLGTVSWNLREM 1348
Query 1379 LAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTL 1438
LAHAEETRKLMP+C++ +AI++TIQRKYKGIK+QEG+VDYG RF+FYTSK VAS+I L
Sbjct 1349 LAHAEETRKLMPICLDVRAIMATIQRKYKGIKVQEGIVDYGVRFFFYTSKEPVASIITKL 1408
Query 1439 NDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPE 1498
N LNE LVTMP+GYVTHGLNLEEAAR MRSLK PA VSVSSPDAVTAYNGYLTSSSKTPE
Sbjct 1409 NSLNEPLVTMPIGYVTHGLNLEEAARCMRSLKAPAVVSVSSPDAVTAYNGYLTSSSKTPE 1468
Query 1499 EHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTS-NPTTFHLDGEVITFDNLK 1557
E+F+ET SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T+ +P FHLDGEV+ D LK
Sbjct 1469 EYFVETTSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTTGSPIEFHLDGEVLPLDKLK 1528
Query 1558 TLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKT 1617
+LLSLREV+TIKVFTTVDN NLHT +VDMSMTYGQQFGPTYLDGADVTKIKPH +HEGKT
Sbjct 1529 SLLSLREVKTIKVFTTVDNTNLHTHIVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKT 1588
Query 1618 FYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLA 1677
F+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNNCYL+
Sbjct 1589 FFVLPSDDTLRSEAFEYYHTIDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLS 1648
Query 1678 TALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQ 1737
+ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM++L Q
Sbjct 1649 SVLLALQQVEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQ 1708
Query 1738 HANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYL 1797
HANL+S KRVLNVVCK CGQ+ TTLKGVEAVMYMGTLSY++ K GV IPC CG+ AT+YL
Sbjct 1709 HANLESAKRVLNVVCKHCGQKTTTLKGVEAVMYMGTLSYDELKTGVSIPCVCGRNATQYL 1768
Query 1798 VQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSS 1857
VQQES FVMMSAPPA+Y+L+ G F CA+EYTGNYQCGHY HIT+KETLY +DGA LTK S
Sbjct 1769 VQQESSFVMMSAPPAEYKLQQGAFLCANEYTGNYQCGHYTHITAKETLYRVDGAHLTKMS 1828
Query 1858 EYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPN 1917
EYKGP+TDVFYKE SYTT IKPV+YKLDGV TEI+PKLD YYKK N+Y+TEQPIDLVP
Sbjct 1829 EYKGPVTDVFYKETSYTTAIKPVSYKLDGVTYTEIEPKLDGYYKKGNAYYTEQPIDLVPT 1888
Query 1918 QPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTP 1977
QP PNASFDNFK C N KFADDLNQ+TG+KKPASREL VTFFPDLNGDVVAIDY+HY+
Sbjct 1889 QPMPNASFDNFKLTCSNTKFADDLNQMTGFKKPASRELTVTFFPDLNGDVVAIDYRHYST 1948
Query 1978 SFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMD 2037
SFKKGAKL+HKPI+WH+N TNK TYKPN WC+RCLWSTKPV+TSNSF+VL ED QGMD
Sbjct 1949 SFKKGAKLVHKPILWHINQTTNKTTYKPNIWCLRCLWSTKPVDTSNSFEVLVVEDTQGMD 2008
Query 2038 NLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMA 2097
NLACE SEEVVENPT+QK+++EC+VKTTEVVG++ILKP+ +K+T+E+GH DLMA
Sbjct 2009 NLACESQTTTSEEVVENPTVQKEIIECDVKTTEVVGNVILKPSEEGVKVTQELGHEDLMA 2068
Query 2098 AYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIV 2157
AYV+ +S+TIKKPNELS LGLKTLATHG AA+NSVPW I Y KPFL + T+N +
Sbjct 2069 AYVEETSITIKKPNELSLALGLKTLATHGAAAINSVPWSKILAYVKPFLGQTAVITSNCI 2128
Query 2158 TRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNY 2217
+C+ RV +NYMPY TLL QLCTFT+STNSRIKAS+PTTIAKN+VKSV K CL+ NY
Sbjct 2129 KKCVQRVFSNYMPYVITLLFQLCTFTKSTNSRIKASLPTTIAKNSVKSVAKLCLDVCINY 2188
Query 2218 LKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVT 2277
+KSP FSKL I++W LLLS+CLGSL Y TA LGV +S+LG+PSYC G RE Y+NS+NVT
Sbjct 2189 VKSPKFSKLFTIVMWLLLLSICLGSLTYVTAVLGVCLSSLGVPSYCDGVRELYINSSNVT 2248
Query 2278 IATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRF 2337
+C G PCSVCLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+LFT+F
Sbjct 2249 TMDFCQGYFPCSVCLSGLDSLDSYPALETIQVTISSYKLDLTFLGLAAEWLLAYMLFTKF 2308
Query 2338 FYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY 2397
FY+LGL+AIMQ FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYYVWKSY
Sbjct 2309 FYLLGLSAIMQAFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYVWKSY 2368
Query 2398 VHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDT 2457
VH++DGC SSTCMMCYKRNRATRVECTTIVNGV+RSFYVYANGG+GFCK HNWNC+NCDT
Sbjct 2369 VHIMDGCTSSTCMMCYKRNRATRVECTTIVNGVKRSFYVYANGGRGFCKAHNWNCLNCDT 2428
Query 2458 FCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHS 2517
FCAGSTFISDEVARDLSLQFKRPINPTDQS+Y+VDSVTVKNG++HLYFDKAGQKTYERH
Sbjct 2429 FCAGSTFISDEVARDLSLQFKRPINPTDQSAYVVDSVTVKNGALHLYFDKAGQKTYERHP 2488
Query 2518 LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALV 2577
LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEES+AKSASVYYSQLMCQPILLLDQALV
Sbjct 2489 LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESAAKSASVYYSQLMCQPILLLDQALV 2548
Query 2578 SDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAA 2637
SDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF+SAA
Sbjct 2549 SDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAA 2608
Query 2638 RQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSAR 2697
RQG VD+DV+TKDV+ECLKLSH SDIEVTGDSCNN+MLTYNKVENMTPRDLGACIDC+AR
Sbjct 2609 RQGVVDTDVDTKDVIECLKLSHHSDIEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNAR 2668
Query 2698 HINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTK 2757
HINAQVAKSHN++L+WNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV+TTK
Sbjct 2669 HINAQVAKSHNVSLVWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTK 2728
Query 2758 IALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVT 2817
I+LKGGK+V+ W K L+KVTL+ + A Y+I PVH +S H +++EIIGYKAI GVT
Sbjct 2729 ISLKGGKVVSTWFKLLLKVTLLCVLAALFCYVIMPVHSLSVHDGYTNEIIGYKAIQDGVT 2788
Query 2818 RDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTT 2877
RDI STD CFANKHA FD+WFSQRGGSY NDK CP++AA+ITRE+GF+VPGLPGT+LR
Sbjct 2789 RDIVSTDDCFANKHAGFDSWFSQRGGSYRNDKNCPVVAAIITREIGFIVPGLPGTVLRAL 2848
Query 2878 NGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTN 2937
NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYCYDTN
Sbjct 2849 NGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTN 2908
Query 2938 VLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVC 2997
+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE GVC
Sbjct 2909 LLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGVC 2968
Query 2998 VSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVV 3057
+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+AI+V
Sbjct 2969 LSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILV 3028
Query 3058 TCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLT 3117
TC AYYFM+FRRAFGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYS+ YLYLTFY T
Sbjct 3029 TCAAYYFMKFRRAFGEYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFYLYLTFYFT 3088
Query 3118 NDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEE 3177
NDVSFLAH+QW MF+P+VPFWIT Y+ CIS KHF+WFFSNYLK+RV+FNGV+FSTFEE
Sbjct 3089 NDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHFHWFFSNYLKKRVMFNGVTFSTFEE 3148
Query 3178 AALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKA 3237
AALCTFLLNKEMYL+LRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCHLAKA
Sbjct 3149 AALCTFLLNKEMYLRLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKA 3208
Query 3238 LNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD 3297
LNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD
Sbjct 3209 LNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD 3268
Query 3298 VVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTA 3357
VYCPRHV+CT+EDMLNPNY+DLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT+
Sbjct 3269 TVYCPRHVVCTAEDMLNPNYDDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTS 3328
Query 3358 NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDY 3417
NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGFNIDY
Sbjct 3329 NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDY 3388
Query 3418 DCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVIN 3477
DCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVIN
Sbjct 3389 DCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVIN 3448
Query 3478 GDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQN 3537
GDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQN
Sbjct 3449 GDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQN 3508
Query 3538 GMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQS 3597
GMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+LVQS
Sbjct 3509 GMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQS 3568
Query 3598 TQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPA 3657
TQWSLFFF+YENAFLPFA+GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMVYMPA
Sbjct 3569 TQWSLFFFVYENAFLPFALGIMAVAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPA 3628
Query 3658 SWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTL 3717
SWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMNV+TL
Sbjct 3629 SWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITL 3688
Query 3718 VYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQ 3777
VYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITGNTLQ
Sbjct 3689 VYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQ 3748
Query 3778 CIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDA 3837
CIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+SIDA
Sbjct 3749 CIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDA 3808
Query 3838 FKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHND 3897
FKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHND
Sbjct 3809 FKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHND 3868
Query 3898 ILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAF 3957
ILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA+
Sbjct 3869 ILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAY 3928
Query 3958 ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQAR 4017
ATAQEAYEQAV+NGDSEVVLKKLKKSLNVAKSEFD DAAMQRKLEKMADQAMTQMYKQAR
Sbjct 3929 ATAQEAYEQAVSNGDSEVVLKKLKKSLNVAKSEFDHDAAMQRKLEKMADQAMTQMYKQAR 3988
Query 4018 SEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDY 4077
SEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV+PDY
Sbjct 3989 SEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDY 4048
Query 4078 NTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAV 4137
TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRANSAV
Sbjct 4049 GTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRANSAV 4108
Query 4138 KLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFP 4197
KLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN KGGRFVLALLSD QDLKWARFP
Sbjct 4109 KLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNAKGGRFVLALLSDHQDLKWARFP 4168
Query 4198 KSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNA 4257
KSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNA
Sbjct 4169 KSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNA 4228
Query 4258 TEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMD 4317
TEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMD
Sbjct 4229 TEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMD 4288
Query 4318 QESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWK 4377
QESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVCGMWK
Sbjct 4289 QESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWK 4348
Query 4378 GYGCSCDQLREPMLQSADAQSFLN 4401
GYGCSCDQLREPM+QSADA +FLN
Sbjct 4349 GYGCSCDQLREPMMQSADASTFLN 4372
>sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus
Rp3/2004 OX=349344 GN=1a PE=3 SV=1
Length=4380
Score = 5891 bits (15282), Expect = 0.0, Method: Composition-based stats.
Identities = 3514/4405 (80%), Positives = 3925/4405 (89%), Gaps = 33/4405 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK GTCG+VE+EKGV
Sbjct 1 MESLVLGINEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKSGTCGIVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQ EQPYVFIKRSDA+ HGH + ELVAEL+G+QYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQPEQPYVFIKRSDAQGTDHGHRVRELVAELDGVQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHS+G DLKS+DLGDELGTDP ED+++NWNTKH SGV REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGVLRELTRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A TRYVDNNFCGPDGYPLECIKDLLARAGK+ CTLSEQLD+I++KRGVYCCR+H HEIAW
Sbjct 181 ALTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCRDHGHEIAW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TCGYL
Sbjct 301 RSVYPVATPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVSEGPNTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + E+GPEHS A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSAADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF+LNEE+AIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFQLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+ +S+L+PL F S+A
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPIKGAWNIGQHRSVLTPLCGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIFSRTL+ A +S+ LQ+AA+TILD IS+ SLRL+DAM++TS+L TN++++MAY
Sbjct 541 AGVIRSIFSRTLDAANHSIPDLQRAAVTILDSISEQSLRLVDAMVYTSNLLTNSVIIMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ TSQWL+N+ T EKL+P+ W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 VTGGLVQQTSQWLSNLLDTTVEKLRPIFAWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNIKDCVKCFVDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAVVG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVCINGLMLLEIK E+YCAL+P ++ TNN F LKGGAPTK VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCINGLMLLEIKANEQYCALSPGLLATNNVFRLKGGAPTKGVTFGEDTVVEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEP--STQYEYGTEDDYQG 957
WS+AT+YLFD+SGE KL+S MYCSFYPPDE+E+ + EEEE + ++EYGTE+DY+G
Sbjct 901 WSVATFYLFDDSGEEKLSSRMYCSFYPPDEEEDCEEYEEEEEVSERTCEHEYGTEEDYKG 960
Query 958 KPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELT 1017
PLEFGA++ +Q EE++EEDWLDD
Sbjct 961 LPLEFGASTDIIQVEEQEEEDWLDD---------------------------AVEAEPEP 993
Query 1018 PVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
+ VN +GYLKLTDNV IK DIVEEA+ P V+VNAAN++LKHGGGVAGALNK
Sbjct 994 EPLHEEPVNQLTGYLKLTDNVAIKCVDIVEEAQNANPMVIVNAANIHLKHGGGVAGALNK 1053
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
ATN AMQ ESD YI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYEN
Sbjct 1054 ATNGAMQKESDHYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYEN 1113
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK 1197
FN ++LLAPLLSAGIFGA P+ SL++CV TVRT VY+ V DK LY+++V +L+ K
Sbjct 1114 FNSQDILLAPLLSAGIFGAKPLQSLQMCVQTVRTQVYIVVNDKVLYEQVVMDYLDSLKPK 1173
Query 1198 QVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYI 1257
K +PK E + K V++ KIKAC++EVTTTLEETKFLT LLL+
Sbjct 1174 VEAPKQEVLPKAEYPK--VDEKSVVQKTIDVKPKIKACIDEVTTTLEETKFLTNKLLLFT 1231
Query 1258 DINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKAL 1317
DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML++AL
Sbjct 1232 DINGKLYQDSKNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLSRAL 1291
Query 1318 RKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLRE 1377
+KVP + YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSWNLRE
Sbjct 1292 KKVPINEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSETPNAKEEILGTVSWNLRE 1351
Query 1378 MLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINT 1437
MLAHAEETRKLMPVC++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS+I
Sbjct 1352 MLAHAEETRKLMPVCMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITK 1411
Query 1438 LNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTP 1497
LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSSSKT
Sbjct 1412 LNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAIVSVSSPDAVTTYNGYLTSSSKTS 1471
Query 1498 EEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVITFDNL 1556
E+HF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRG+K VY+T +P FHLDGEV+ D L
Sbjct 1472 EDHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGEKIVYHTLESPVKFHLDGEVLPLDKL 1531
Query 1557 KTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGK 1616
K+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQ GPTYL+GADVTKIKPH +HEGK
Sbjct 1532 KSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQLGPTYLEGADVTKIKPHVNHEGK 1591
Query 1617 TFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYL 1676
TF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNNCYL
Sbjct 1592 TFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYL 1651
Query 1677 ATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLF 1736
++ LL LQQIE+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM++L
Sbjct 1652 SSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLL 1711
Query 1737 QHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKY 1796
QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+ AT+Y
Sbjct 1712 QHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKMGVSIPCVCGRDATQY 1771
Query 1797 LVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKS 1856
LVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA LTK
Sbjct 1772 LVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKM 1831
Query 1857 SEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVP 1916
SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPIDL+P
Sbjct 1832 SEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLIP 1891
Query 1917 NQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYT 1976
QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY+HY+
Sbjct 1892 TQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYS 1951
Query 1977 PSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGM 2036
SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED QGM
Sbjct 1952 ASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGM 2011
Query 2037 DNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLM 2096
DNLACE +P EEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+ H DLM
Sbjct 2012 DNLACESQQPTPEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELDHEDLM 2071
Query 2097 AAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNI 2156
AAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + TT+N
Sbjct 2072 AAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWGKILAYVKPFLGQAAVTTSNC 2131
Query 2157 VTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFN 2216
R + R+ NYMPY TLL QLCTFT+STNSRI+AS+PTTIAKN+V+ + + CL+A N
Sbjct 2132 AKRLVQRMFNNYMPYVLTLLFQLCTFTKSTNSRIRASLPTTIAKNSVRGIVRLCLDAGIN 2191
Query 2217 YLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNV 2276
Y+KSP FSKL I +W LLLS+CLGSLIY TAALGVL+SN G PSYC+G RE YLNS+NV
Sbjct 2192 YVKSPKFSKLFTIAMWLLLLSICLGSLIYVTAALGVLLSNFGAPSYCSGVRESYLNSSNV 2251
Query 2277 TIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTR 2336
T +C GS PCSVCLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEWF AY+LFT+
Sbjct 2252 TTMDFCEGSFPCSVCLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWFFAYMLFTK 2311
Query 2337 FFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKS 2396
FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY+WKS
Sbjct 2312 FFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKS 2371
Query 2397 YVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCD 2456
YVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC+NCD
Sbjct 2372 YVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCD 2431
Query 2457 TFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERH 2516
TFCAGSTFISDEVARDLSLQFKRPINPTDQSSY+VDSV VKNG++HLYFDKAGQKTYERH
Sbjct 2432 TFCAGSTFISDEVARDLSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAGQKTYERH 2491
Query 2517 SLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQAL 2576
LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES+AKSASVYYSQLMCQPILLLDQAL
Sbjct 2492 PLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPILLLDQAL 2551
Query 2577 VSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISA 2636
VSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF+SA
Sbjct 2552 VSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSA 2611
Query 2637 ARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSA 2696
+RQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACIDC+A
Sbjct 2612 SRQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNA 2671
Query 2697 RHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTT 2756
RHINAQVA+SHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV+TT
Sbjct 2672 RHINAQVARSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITT 2731
Query 2757 KIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGV 2816
KI+LKGGKIV+ W K ++K TL+ + A + Y++ PVH++S H +++EIIGYKAI GV
Sbjct 2732 KISLKGGKIVSTWFKIMLKATLLCVLAALVCYIVMPVHILSVHGGYTNEIIGYKAIQDGV 2791
Query 2817 TRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRT 2876
TRDI STD CFANKHA FD+WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT+LR
Sbjct 2792 TRDIVSTDDCFANKHAGFDSWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRA 2851
Query 2877 TNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDT 2936
NGDFLHFLPRVFSAVGNICYTPSKLIEY+DF+TSACVLAAECTIFKDA GKPVPYCYDT
Sbjct 2852 INGDFLHFLPRVFSAVGNICYTPSKLIEYSDFSTSACVLAAECTIFKDAMGKPVPYCYDT 2911
Query 2937 NVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGV 2996
N+LEGS++Y LRPDTRYVLMDGSIIQFPN YLEGSVRVVTTFD+EYCRHGTCERSEAG+
Sbjct 2912 NLLEGSISYSELRPDTRYVLMDGSIIQFPNAYLEGSVRVVTTFDAEYCRHGTCERSEAGI 2971
Query 2997 CVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIV 3056
C+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+AI+
Sbjct 2972 CLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAIL 3031
Query 3057 VTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYL 3116
VTC AYYFM+FRRAFGEY+HVVA N LFLMSFT+LCL P YSFLPGVYSV YLYLTFY
Sbjct 3032 VTCAAYYFMKFRRAFGEYNHVVAANAPLFLMSFTILCLAPAYSFLPGVYSVFYLYLTFYF 3091
Query 3117 TNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE 3176
TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KHF+WFF+NYL++RVVFNGV+FSTFE
Sbjct 3092 TNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHFHWFFNNYLRKRVVFNGVTFSTFE 3151
Query 3177 EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAK 3236
EAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCHLAK
Sbjct 3152 EAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAK 3211
Query 3237 ALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLD 3296
ALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLD
Sbjct 3212 ALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLD 3271
Query 3297 DVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDT 3356
D VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LKVDT
Sbjct 3272 DTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDT 3331
Query 3357 ANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNID 3416
+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGFNID
Sbjct 3332 SNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNID 3391
Query 3417 YDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVI 3476
YDCVSFCYMHHMELPT VHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYAAVI
Sbjct 3392 YDCVSFCYMHHMELPTEVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVI 3451
Query 3477 NGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQ 3536
NGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKELLQ
Sbjct 3452 NGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQ 3511
Query 3537 NGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQ 3596
NGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ KR +KGTHHW+LLT LTSLL+LVQ
Sbjct 3512 NGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKRIVKGTHHWMLLTFLTSLLILVQ 3571
Query 3597 STQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP 3656
STQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMVYMP
Sbjct 3572 STQWSLFFFVYENAFLPFTLGIMAVAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMP 3631
Query 3657 ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLT 3716
ASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL+LMTARTVYDD ARRVWTLMNV+T
Sbjct 3632 ASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVWTLMNVIT 3691
Query 3717 LVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTL 3776
LVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITGNTL
Sbjct 3692 LVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTL 3751
Query 3777 QCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSID 3836
QCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+SID
Sbjct 3752 QCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSID 3811
Query 3837 AFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHN 3896
AFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHN
Sbjct 3812 AFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHN 3871
Query 3897 DILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA 3956
DILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA
Sbjct 3872 DILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA 3931
Query 3957 FATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQA 4016
+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR+AAMQRKLEKMADQAMTQMYKQA
Sbjct 3932 YATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRNAAMQRKLEKMADQAMTQMYKQA 3991
Query 4017 RSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPD 4076
RSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV+PD
Sbjct 3992 RSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPD 4051
Query 4077 YNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSA 4136
Y TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+M+NS NLAWPLIVTALRANSA
Sbjct 4052 YGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMENSSNLAWPLIVTALRANSA 4111
Query 4137 VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARF 4196
VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLKWARF
Sbjct 4112 VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARF 4171
Query 4197 PKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGN 4256
PKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL+FIKGLNNLNRGMVLGSLAATVRLQAGN
Sbjct 4172 PKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLHFIKGLNNLNRGMVLGSLAATVRLQAGN 4231
Query 4257 ATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANM 4316
ATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANM
Sbjct 4232 ATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANM 4291
Query 4317 DQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMW 4376
DQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVCGMW
Sbjct 4292 DQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMW 4351
Query 4377 KGYGCSCDQLREPMLQSADAQSFLN 4401
KGYGCSCDQLREPM+QSADA +FLN
Sbjct 4352 KGYGCSCDQLREPMMQSADASTFLN 4376
>sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus
279/2005 OX=389167 GN=1a PE=3 SV=1
Length=4388
Score = 5886 bits (15269), Expect = 0.0, Method: Composition-based stats.
Identities = 3521/4411 (80%), Positives = 3922/4411 (89%), Gaps = 37/4411 (1%)
Query 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
MESL G +EKTHVQLSLPVLQVRDVLVRGFGDSVEE L+EAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLALGVSEKTHVQLSLPVLQVRDVLVRGFGDSVEEALAEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
LPQLEQPYVFIKRSDA+ HG+ +VELVAEL+GIQYGRSG TLGVLVPHVGE PVAYR
Sbjct 61 LPQLEQPYVFIKRSDAQGTNHGYKVVELVAELDGIQYGRSGTTLGVLVPHVGETPVAYRN 120
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLG ELGTDP ED+++NWNTKH GV REL+RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGVELGTDPIEDYEQNWNTKHGGGVLRELIRELNGG 180
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
A+TRYVDNNFCGPDGYPLECIKDLLARAGK+ CTLSEQLD+I++KRGVYCCREHEHEI W
Sbjct 181 AFTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
+TERSEKSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 FTERSEKSYERQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
RSVYPVA+P ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
P NAVVK+ CPAC + EVGPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PANAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
AYWVPRASANIG +HTG+ G+ E LN++L+EIL +++VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASANIGASHTGITGDNVETLNEDLMEILNRDRVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
SAST AFV+TVKGLDYK FK IVESCGNFKVT+G+AKKGAWNIG++KSIL+PLY F S+A
Sbjct 481 SASTCAFVDTVKGLDYKTFKDIVESCGNFKVTRGRAKKGAWNIGQEKSILTPLYGFPSQA 540
Query 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
A V+RSIF+R L+TA +S+ LQ+AAITILDGIS+ SLRLIDAM++TSDL TN+++VMAY
Sbjct 541 AGVIRSIFTRALDTANHSIPDLQRAAITILDGISEQSLRLIDAMVYTSDLLTNSVIVMAY 600
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
+TGG+VQ +QWL+N+ GT +KLKPV W+E K G+EFLRD WEI+KF+ T +IV
Sbjct 601 VTGGLVQQITQWLSNMLGTTVDKLKPVFTWVEAKLSAGIEFLRDAWEILKFLVTGVFDIV 660
Query 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
GQI + +KE V+ F ++NK L +C D +II GAKL+ LNLGE F+ SKGLYR+C
Sbjct 661 KGQIQVASDNLKECVKAFLDVLNKALEMCIDQVIIAGAKLRTLNLGEVFIAQSKGLYRQC 720
Query 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
++ +E+ LLMPL+APKE+ F EG++ T +EEVVLK G+L+ LE P ++G
Sbjct 721 IRGKEQLQLLMPLRAPKEVTFFEGDSHDTVFTSEEVVLKNGELEALETPVDSFTNGAVIG 780
Query 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
TPVC+NGLMLLE+KD E+YCAL+P ++ TNN F+LKGGAP K VTFG+DTV+EVQGYK+V
Sbjct 781 TPVCVNGLMLLELKDKEQYCALSPGLLATNNVFSLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 841 KITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ--YEYGTEDDYQG 957
WS+AT+YLFD++GE KL+S MYCSFYPPDE+E+ + E+EE P +EYGTEDDY+G
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCEEYEDEEEIPEETCEHEYGTEDDYKG 960
Query 958 KPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELT 1017
PLEFGA++ QQ +++ + + E
Sbjct 961 LPLEFGASTE----------------IQQVDEEEEEDWLEEAIAAKPEPE---------- 994
Query 1018 PVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNK 1077
+ VN F+GYLKLTDNV IK DIV+EA+ KPTV+VNAANV+LKHGGGVAGALNK
Sbjct 995 -PLPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQHAKPTVIVNAANVHLKHGGGVAGALNK 1053
Query 1078 ATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYEN 1137
ATN AMQ ESDDYI NGPL VGGSC+LSGHNLAK C+HVVGPN+N GED+QLLK+AY N
Sbjct 1054 ATNGAMQQESDDYIKKNGPLTVGGSCLLSGHNLAKKCMHVVGPNLNAGEDVQLLKAAYAN 1113
Query 1138 FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK 1197
FN +VLLAPLLSAGIFGA P+ SL++CV+TVRT VY AV D++LYD +V +L+ K
Sbjct 1114 FNSQDVLLAPLLSAGIFGAKPLQSLKMCVETVRTQVYFAVNDQDLYDHVVLGYLDSLKPK 1173
Query 1198 --QVEQKIAEIPKEEVKPFITESKPSVEQ----RKQDDKKIKACVEEVTTTLEETKFLTE 1251
Q+ E+ ++ +T+ +E+ K D K KA +EEV T+LEETKFLT
Sbjct 1174 VETPTQENLELKEQPAVETLTQENLELEELPVIEKPVDVKFKARIEEVNTSLEETKFLTS 1233
Query 1252 NLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTE 1311
LLL+ DING L+ DS ++ D+ FL+KDAPYIVGDV+ G +T V+IP KKAGGTTE
Sbjct 1234 RLLLFADINGKLYQDSQNMLRGEDMFFLEKDAPYIVGDVISSGDITCVIIPAKKAGGTTE 1293
Query 1312 MLAKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTV 1371
MLAKAL+KVP YITTYPGQG GYT+EEAKT L+KCKS FY+LPS N+K+EILGTV
Sbjct 1294 MLAKALKKVPVSEYITTYPGQGCAGYTLEEAKTALRKCKSVFYVLPSKTPNDKEEILGTV 1353
Query 1372 SWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTV 1431
SWNLREMLAHAEETRKLM +C++ KA++STI R+YKGIK+QEG+VDYG RF+FYTSK V
Sbjct 1354 SWNLREMLAHAEETRKLMLICMDVKALMSTIHRRYKGIKVQEGIVDYGVRFFFYTSKEPV 1413
Query 1432 ASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLT 1491
AS+I LN LNE LVTMP+GYVTHGLNLEEAAR MRSLK PA VSVSSPDAVT YNGYLT
Sbjct 1414 ASIITKLNLLNEPLVTMPIGYVTHGLNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLT 1473
Query 1492 SSSKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEV 1550
SSSKT EEHFIET+SLAG Y+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGEV
Sbjct 1474 SSSKTSEEHFIETVSLAGMYRDWSYSGQRTELGVEFLKRGDKVVYHTVGSPIQFHLDGEV 1533
Query 1551 ITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPH 1610
+ D LK+LLSLREVRTIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH
Sbjct 1534 LLLDKLKSLLSLREVRTIKVFTTVDNTNLHTQIVDMSMTYGQQFGPTYLDGADVTKIKPH 1593
Query 1611 NSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWA 1670
HEGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQ+ GLTSIKWA
Sbjct 1594 AKHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQIGGLTSIKWA 1653
Query 1671 DNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRE 1730
DNNCYL++ LL LQQIE+KFN PALQ+AYYRARAG+AANFCALILAY N+TVGELGDVRE
Sbjct 1654 DNNCYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAYSNRTVGELGDVRE 1713
Query 1731 TMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCG 1790
TM++L QHANL+S KRVLNVVCKTCGQ+ TTL GVEAVMYMGTLSYE+ K GV IPC CG
Sbjct 1714 TMTHLLQHANLESAKRVLNVVCKTCGQKSTTLTGVEAVMYMGTLSYEELKTGVTIPCICG 1773
Query 1791 KQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDG 1850
+ AT+YLVQQES FVMMSAPP++Y L+ G F CA+EYTG+YQCGHY H+T KETLY IDG
Sbjct 1774 RDATQYLVQQESSFVMMSAPPSEYTLQQGAFLCANEYTGSYQCGHYTHVTVKETLYRIDG 1833
Query 1851 ALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQ 1910
A LTK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV+ TEI PKLD YYKKDN+Y+TEQ
Sbjct 1834 AYLTKMSEYKGPVTDVFYKEISYTTTIKPVSYKLDGVIYTEIQPKLDEYYKKDNAYYTEQ 1893
Query 1911 PIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAI 1970
PIDLVP QP PNASFDNFK C N KFADDLNQ+TG+KKPASREL VTFFPDLNGDVVAI
Sbjct 1894 PIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFKKPASRELSVTFFPDLNGDVVAI 1953
Query 1971 DYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKS 2030
DY+HY+ SFKKGAKLLHKPI+WH+N TNK TYKPNTWC+RCLWSTKPVETSNSF+VL+
Sbjct 1954 DYRHYSASFKKGAKLLHKPIIWHINQTTNKTTYKPNTWCLRCLWSTKPVETSNSFEVLEV 2013
Query 2031 EDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEV 2090
ED QGMDNLACE P SEEVVENPTIQK+V+EC+VKT EVVG++ILKP+ +K+T+E+
Sbjct 2014 EDTQGMDNLACESQTPTSEEVVENPTIQKEVIECDVKTIEVVGNVILKPSEEGVKVTQEL 2073
Query 2091 GHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVV 2150
GH DLMAAYV+ +S+TIKKPNELS LGL+TLATHG AA+NSVPW I Y KPFL +
Sbjct 2074 GHEDLMAAYVEETSITIKKPNELSLALGLRTLATHGAAAINSVPWSKILAYVKPFLGQAA 2133
Query 2151 STTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFC 2210
TTTN + RC+ RV NYMPY TLL QLCTFTRSTNSRI+AS+PTTIAKN+VKSV K C
Sbjct 2134 VTTTNCIKRCVQRVFNNYMPYVITLLFQLCTFTRSTNSRIRASLPTTIAKNSVKSVAKLC 2193
Query 2211 LEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGY 2270
L+ NY+KSP FSKL I +W LLLS+CLGSLIY TAA GVL+SNLG+PSYC G RE Y
Sbjct 2194 LDVCINYVKSPKFSKLFTIAMWLLLLSICLGSLIYVTAAFGVLLSNLGIPSYCDGVRESY 2253
Query 2271 LNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLA 2330
+NS+NVT +C GS CSVCL+GLDSLD+YP+LETIQ+TISS+K DLT+ GL AEWFLA
Sbjct 2254 VNSSNVTTMDFCEGSFLCSVCLNGLDSLDSYPALETIQVTISSYKLDLTSLGLAAEWFLA 2313
Query 2331 YILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASF 2390
Y+LFT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFA
Sbjct 2314 YMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFAFC 2373
Query 2391 YYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNW 2450
YYVWKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNW
Sbjct 2374 YYVWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKAHNW 2433
Query 2451 NCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQ 2510
NC+NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSY+VDSV VKNG++HLYFDKAGQ
Sbjct 2434 NCLNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAGQ 2493
Query 2511 KTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPIL 2570
KTYERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES+AKSASVYYSQLMCQPIL
Sbjct 2494 KTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPIL 2553
Query 2571 LLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVL 2630
LLDQALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VL
Sbjct 2554 LLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVL 2613
Query 2631 STFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGA 2690
STF+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGA
Sbjct 2614 STFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGA 2673
Query 2691 CIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQV 2750
CIDC+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQV
Sbjct 2674 CIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQV 2733
Query 2751 VNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYK 2810
VN +TTKI+LKGGKIV+ W K ++K TL+ + A Y+I PVH +S H +++EIIGYK
Sbjct 2734 VNAITTKISLKGGKIVSTWFKLMLKATLLCVLAALFCYIIMPVHSLSVHDGYTNEIIGYK 2793
Query 2811 AIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLP 2870
AI GVTRDI +TD CFANKHA FD+WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLP
Sbjct 2794 AIQDGVTRDIMATDDCFANKHAGFDSWFSQRGGSYRNDKSCPVVAAIITREIGFIVPGLP 2853
Query 2871 GTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPV 2930
GT+LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPV
Sbjct 2854 GTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPV 2913
Query 2931 PYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCE 2990
PYCYDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCE
Sbjct 2914 PYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCE 2973
Query 2991 RSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAG 3050
RSEAGVC+STSGRWVLNN++YR+LPGVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAG
Sbjct 2974 RSEAGVCLSTSGRWVLNNEHYRALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAG 3033
Query 3051 GIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYL 3110
GI+AI+VTC AYYFM+FRRAFGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYS+ YL
Sbjct 3034 GIIAILVTCAAYYFMKFRRAFGEYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFYL 3093
Query 3111 YLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGV 3170
YLTFY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNGV
Sbjct 3094 YLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGV 3153
Query 3171 SFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAA 3230
+FSTFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAA
Sbjct 3154 TFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAA 3213
Query 3231 CCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTL 3290
CCHLAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTL
Sbjct 3214 CCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTL 3273
Query 3291 NGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVL 3350
NGLWLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L
Sbjct 3274 NGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLL 3333
Query 3351 KLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGS 3410
+LKVDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN+TIKGSFLNGSCGS
Sbjct 3334 RLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNYTIKGSFLNGSCGS 3393
Query 3411 VGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAW 3470
VGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAW
Sbjct 3394 VGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAW 3453
Query 3471 LYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAS 3530
LYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+
Sbjct 3454 LYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAA 3513
Query 3531 LKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTS 3590
LKELLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTS
Sbjct 3514 LKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTS 3573
Query 3591 LLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYF 3650
LL+LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYF
Sbjct 3574 LLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYF 3633
Query 3651 NMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWT 3710
NMVYMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLL+LMTARTVYDD ARRVWT
Sbjct 3634 NMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVWT 3693
Query 3711 LMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFF 3770
LMNV+TLVYKVYYGN+LDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ F
Sbjct 3694 LMNVITLVYKVYYGNSLDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLF 3753
Query 3771 ITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLP 3830
ITGNTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLP
Sbjct 3754 ITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLP 3813
Query 3831 PKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQ 3890
PK+SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQ
Sbjct 3814 PKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQ 3873
Query 3891 CVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSS 3950
CVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSS
Sbjct 3874 CVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSS 3933
Query 3951 LPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMT 4010
LPSYAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMT
Sbjct 3934 LPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMT 3993
Query 4011 QMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKL 4070
QMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKL
Sbjct 3994 QMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKL 4053
Query 4071 MVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTA 4130
MVV+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNS NLAWPLIVTA
Sbjct 4054 MVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSQNLAWPLIVTA 4113
Query 4131 LRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQD 4190
LRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QD
Sbjct 4114 LRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQD 4173
Query 4191 LKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATV 4250
LKWARFPKSDGTGTIYTELEPPCRFVTDTP+GPKVKYLYFIKGLNNLNRGMVLGSLAATV
Sbjct 4174 LKWARFPKSDGTGTIYTELEPPCRFVTDTPRGPKVKYLYFIKGLNNLNRGMVLGSLAATV 4233
Query 4251 RLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITV 4310
RLQAGNATEVPANS VLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITV
Sbjct 4234 RLQAGNATEVPANSAVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITV 4293
Query 4311 TPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVC 4370
TPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIP TCANDPVGFTLKNTVC
Sbjct 4294 TPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPATCANDPVGFTLKNTVC 4353
Query 4371 TVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
TVCG WKGYGCSCDQLREPM+QSADA +FLN
Sbjct 4354 TVCGTWKGYGCSCDQLREPMMQSADASTFLN 4384
>sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus
HKU5 OX=694008 GN=1a PE=3 SV=1
Length=4481
Score = 4633 bits (12016), Expect = 0.0, Method: Composition-based stats.
Identities = 1497/4575 (33%), Positives = 2331/4575 (51%), Gaps = 297/4575 (6%)
Query 9 NEKT--HVQLSLPVLQVRDVLV---RGFGDSVEEVLSEARQHLKDGTCGLV--EVEKGVL 61
EK HV L + D+++ F D E + L G+ L + KG +
Sbjct 22 TEKRTDHVSLKASLCDAGDLVLKISPWFMDG-ESAYKHVSEQLSKGSKLLFVPQTLKGFI 80
Query 62 PQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETL-----GVLVPHVGEIPV 116
L P V++ MV +A G G TL G+ P ++
Sbjct 81 RHLPGPRVYLVERLTGGTYSDPFMVNQLAYQNAAGEGVIGTTLQGKRVGMFFPFDADLVT 140
Query 117 AYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRE 176
+ LLRK KG GG+ + D + PY D + ++ L+++
Sbjct 141 GEFQFLLRK---KGFGGNRFR------DAPWDYNWTPYSDLMDALEADPCGKYSQSLLKK 191
Query 177 LNGGAYTRYVDNNFCGPDGYPLECIKDLLARAG--KASCTLSEQLDFIDTKRGVYCCREH 234
L GG +T +D CG +G P+ L+A G K + +E D+ R + +
Sbjct 192 LVGGDFTP-IDQYMCGKNGKPIAEFAALMASEGITKLADVEAEVKSRTDSDRYI-VFKNK 249
Query 235 EHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLD 294
+ I W +R + +Y Q+ F + + DT + P F + S I+ I P +
Sbjct 250 LYRIVWNVQRKDVAYSKQSAFTMNSIVQLDTME-DVPRHSFTIGSEIQVIAPSTAVQANG 308
Query 295 GFMGRIRSVYPVASPN---ECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTK 351
+ R +Y E N + S + C CG+ SW TG+ V+ CG
Sbjct 309 HLNLKQRLLYAFYGKQAVSEPNYIYHSAYVDCTSCGKGSWLTGNAVQGFACDCGAHYCAN 368
Query 352 E-GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRT--IAFGG 408
+ + G + +NAV+ CP + E +H+L + + K + G+T + +GG
Sbjct 369 DVDLQSSGLVRKNAVLLTTCPCNKDGEC--KHTLPQLVSMMTDKCDVEVVGKTFILTYGG 426
Query 409 CVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEKVNINIV 464
+++Y+GC +++PRA + + + G G + E L++ + IN V
Sbjct 427 VIYAYMGCSGGTMHFIPRAKSCVS-KIGDAIFTGCTGTWSKVCETANLFLERAQHAINFV 485
Query 465 GDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIG 524
+F L E + +L+ ++S + + ++ + + G + VT G +G N+G
Sbjct 486 NEFVLTETVVALLSGTTSSIEELRDLCRNATFEKVRDYLTPRG-WIVTMGSYIEGVINVG 544
Query 525 EQKSILSPLYA-----------FASEAARVVR--SIFSRTLETAQNSVRVLQKAAITILD 571
+ L A F AA + S TL+ +S+ + I
Sbjct 545 AAGVCNAALNAPFIVLSGLGESFKKVAATPWKLCSSLRETLDHYADSI-TYRVFPYDIPC 603
Query 572 GISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWL 631
++ Y+ L+D + T + V Y+ V QLT+ +F + + +
Sbjct 604 DVTDYTALLLDCAVLTGA---SAYFVARYVDEKVEQLTNL----VFSSCQSAVAAFVQAC 656
Query 632 EEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCAD 691
+K +F+ D + ++K +S V + ++ F +++K + L
Sbjct 657 MSTYKATAKFISDMFTLIKVVSERLYVYTSVGFVVVGDYSSQLLKQFMHILSKAMQLLHT 716
Query 692 SIIIGGAKLKAL--NLGETFVTHSKGLYRKCVKSR---EETGLLMPLKAPKEIIFL---- 742
++ G+KL ++ N ++ V S Y + R ++ L++P K+ I +
Sbjct 717 TVSWAGSKLPSVVYNGRDSLVFPSGTYYCVSTQGRSLQDQFDLVIPGDLSKKQIGILEPT 776
Query 743 -EGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLE-IKDTEK-Y 799
T+ ++ T V + G L+P ++ + E +VG V I+ + + ++D+E +
Sbjct 777 PNSTTVDKKINTNVVEVVVGQLEPTKEHSPEL----VVGDYVIISNKIFVRSVEDSETVF 832
Query 800 CALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSVNITFELDERIDKVL-NEKC 857
L + + F LKGGAP K V FG + E+ +SV++ +++ +D +L +
Sbjct 833 YPLCTDGKIVPTLFRLKGGAPPKGVKFGGEQTKEITAVRSVSVDYDVHPVLDALLAGSEL 892
Query 858 SAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLA 917
+ +TVE V +F VV D VI+ L + G DL++++ Y+++ G+ +
Sbjct 893 ATFTVEKDLPVKDFVDVVKDEVIELLSKLLRGYNVDGFDLEDFADTPCYVYNAEGDLAWS 952
Query 918 SHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEE 977
S M S P +E EEE D + E E ++ ED+ + A A+ P E+ +
Sbjct 953 STMTFSVNPVEEVEEECDDDYVEDEYLSEEMLVEEDEN-----SWAAAVEAVIPMEDVQL 1007
Query 978 DWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDN 1037
D L + + D +E T VEV +E + V EV S
Sbjct 1008 DTLVAEIDVSEPADDVAEQAST----EEVEVPSACVLEASQVANAAEVESCEA------- 1056
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
E + + NAA A + A ++ +
Sbjct 1057 ---------EVSSSIPLHEDANAA-----------KANDCAEGMPALDSTETVSKLSVDT 1096
Query 1098 KVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGAD 1157
VG + + + + + ++ P
Sbjct 1097 PVGDVTQDDATSSNATVIS---------------EDVHTATHSKGLVAVP-------EVV 1134
Query 1158 PIHSLRVCVDTVRTN---VYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPF 1214
P +L V+ +R+ + K +V + ++V++ AE P + K
Sbjct 1135 PEKALGTSVERMRSTSEWTVVETSLKQETAVIVKN-DSSAKPQRVKKPKAENPLKNFKHI 1193
Query 1215 ITESKPSVEQ--RKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGNLHPDSATLVS 1272
+ + ++ + + C+ +L I + S LV
Sbjct 1194 VLNNDVTLVFGDAIAVARATEDCIL--------VNAANTHLKHGGGIAAAIDRASGGLVQ 1245
Query 1273 DIDITFLKKDAPYIVGD-VVQEGVLTA-----VVIPTKKAGGTTEMLA---KALRKVPTD 1323
++ P VGD + +G A VV P +A ++L KA K P
Sbjct 1246 AESDDYVNFYGPLNVGDSTLLKGHGLATGILHVVGPDARANQDIQLLKRCYKAFNKYPL- 1304
Query 1324 NYITTYPGQGLN--------GYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNL 1375
++ G+ Y + T ++ + + + + L
Sbjct 1305 -VVSPLISAGIFCVEPRVSLEYLLSVVHTKTYVVVNSEKVYNDLAAPKPPTGLTYSHEGW 1363
Query 1376 REMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLI 1435
R ++ +A+ +C + A ++ + + + VD G ++Y Y+SK + +I
Sbjct 1364 RGIIRNAKSFGFTCFICTDQSANAKLLKGRGVDLTKKTQTVD-GVKYYLYSSKDPLTDII 1422
Query 1436 NTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSK 1495
N + + MP+GYVTHGL+L +A + ++ + VP ++S D V N + + +
Sbjct 1423 TAANAC-KGICAMPIGYVTHGLDLAQAGQQVKKITVPYVCLLASKDQVPILNSDV--AVQ 1479
Query 1496 TPEEHFIETISLAGSYKDWSY-SGQSTQLGI---EFLKRGDKSVYYTSNPTTFHLDGEVI 1551
TPE+ FI T+ G Y W +G+ G+ + L D+++ Y N +
Sbjct 1480 TPEQSFINTVIANGGYHCWHLVTGELIVKGVSYRKLLNWSDQTICYADNKFYVVKGQIAL 1539
Query 1552 TFDNLKTLLSLR-----EVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTK 1606
FD+L+ + + + + V T+D +N T V++ + TY Q G + G+D++
Sbjct 1540 PFDSLEKCRTYLTSRAAQQKNVDVLVTIDGVNFRTVVLNNTTTYRVQLGSVFYKGSDISD 1599
Query 1607 IKPHNSHEGKTFYVLPNDD-TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLT 1665
P G+ Y+ N + E Y T D +FL RY S L KKWKY +G+
Sbjct 1600 TIPTEKMSGEAVYLADNLSEAEKAVLSEVYGTADTAFLHRYYSLLALVKKWKYTVHDGVK 1659
Query 1666 SIKWADNNCYLATALLTLQQI-ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGE 1724
S+K NNCY+ +L L + E+KF PALQ AY + + G++ F ALI+AY + T GE
Sbjct 1660 SLKLNSNNCYVNVTMLMLDMLKEIKFIVPALQAAYLKHKGGDSTEFIALIMAYGDCTYGE 1719
Query 1725 LGDVRETMSYLFQHANLDS-CKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGV 1783
D + + A L + K V C CG Q TT G++A +Y+G S ++
Sbjct 1720 PDDASRLLHTILSKAELTTQAKMVWRQWCNVCGVQDTTTTGLKACIYVGMNSLDELHATH 1779
Query 1784 QIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTG-------NYQCGHY 1836
+ C CG + LV+ +P++++S + + + +YT GHY
Sbjct 1780 EECCQCGDVRKRQLVEHNAPWLLLSGLNEAKVMTPTSQSAGPDYTAFNVFQGVETSVGHY 1839
Query 1837 KHITSKETL-YCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPK 1895
H+ K+ L Y D L+K+S+ K +TDV+Y + Y+ V Y LDG ++DP
Sbjct 1840 LHVRVKDNLLYKYDSGSLSKTSDMKCKMTDVYYPKQRYSADCNVVVYSLDGNTWADVDPD 1899
Query 1896 LDNYYKKDNSYFTEQP-IDLVPNQPYPNASFDNFKFVCDN-----IKFADDLNQLTGYK- 1948
L +Y KD YFT++P I+ P + + N V + + N L G+
Sbjct 1900 LSAFYMKDGKYFTKKPVIEYSPATILSGSVYTNSCLVGHDGTIGSDAISSSFNNLLGFDN 1959
Query 1949 -KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNT 2007
KP S++L +FFPD GDV+ +Y Y P +K GA L KPI+W N+ + A K N
Sbjct 1960 SKPVSKKLTYSFFPDFEGDVILTEYSTYDPIYKNGAMLHGKPILWVNNSKFDSALNKFNR 2019
Query 2008 WCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLAC-EDLKPVSE-EVVENPTIQKDVLECN 2065
+R ++ PV N + VL+ Q ++ A ED KP S +V E+ + +++C
Sbjct 2020 ATLRQVYDIAPVTLENKYTVLQDNQIQQVEVEAPKEDAKPQSPVQVAEDIDNKLPIIKCK 2079
Query 2066 VKTTEVVGD-IILKPANNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLA 2123
V D + + + +G DL A YVD N L + K N S + + T+
Sbjct 2080 GLKKPFVKDGYSFVNDPQGVNVIDTLGIDDLRALYVDRNLRLIVLKENNWSALFNIHTVE 2139
Query 2124 THGLAAVNSVPWDT----IANYAKPFLNKVVSTTTNIVT---RCLNRVCTNYMP------ 2170
L+ + + T I A + S T N+ T + L R+ N +
Sbjct 2140 KGDLSVIAASGSITRRVKILLGASSLFAQFASVTVNVTTAMGKALGRMTRNVITNTGIIG 2199
Query 2171 YFFTLLLQL----CTFTRSTN-SRIKASMPTTIAKNTVKS-VGKFCLEASFNYLKSPNFS 2224
F LL L TF +S N S +K + V + V K C A+++ L F
Sbjct 2200 QGFALLKMLLILPFTFWKSKNQSTVKVEVGALRTAGIVTTNVVKQCASAAYDVL-VVKFK 2258
Query 2225 KLINIIIWFLLLSVC------------------LGSLIYSTAALGVLM------SNLGMP 2260
++ LL +C L S + A G+L S LG+
Sbjct 2259 RIDWKSTLRLLFLICTTGLLLSSLYYLFLFHQVLTSDVMLDGAEGMLATYRELRSYLGIH 2318
Query 2261 SYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLT 2319
S C G E Y N + + +C+ S C+ CL G DSL Y + + IQ ++S+ ++
Sbjct 2319 SLCDGMVEAYRN-VSYDVNDFCSNRSALCNWCLIGQDSLTRYSAFQMIQTHVTSYVINID 2377
Query 2320 AFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFA--VHFISNSWLMWLIINLVQMAPI 2377
V E+ LAY+L+T F VL L Q FFSY V++ S ++L+ V P+
Sbjct 2378 WVWFVMEFALAYVLYTSTFNVLLLVVSSQYFFSYTGAFVNWRSYNYLVSGYFFCVTHIPL 2437
Query 2378 SAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVY 2437
+VR+Y F A +++ + Y HV++GC + C++CYKRNR TRVE +T+V G +R+FY+
Sbjct 2438 LGLVRIYNFLACLWFLRRFYNHVINGCKDTACLLCYKRNRLTRVEASTVVCGSKRTFYIV 2497
Query 2438 ANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVK 2497
ANGG FC HNWNCV+CDT G+TFI +EVA DL+ +R + PTD+S Y V+SVTVK
Sbjct 2498 ANGGTSFCCRHNWNCVDCDTAGIGNTFICEEVANDLTTSLRRLVKPTDKSHYYVESVTVK 2557
Query 2498 NGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANN----TKGSLPINVIVFDGKSKCEESS 2553
+ + L++ + G YER+ L +F NLD L+ G N +++D + +E+
Sbjct 2558 DSVVQLHYSREGASCYERYPLCYFTNLDKLKFKEVCKTPTGIPEHNFLIYDSSDRGQENL 2617
Query 2554 AKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLV 2613
A+SA VYYSQ++ +P+LL+D +V+ VGDS E+A KM D+YVN+F S F V +KL LV
Sbjct 2618 ARSACVYYSQVLSKPMLLVDSNMVTTVGDSREIASKMLDSYVNSFISLFGVNRDKLDKLV 2677
Query 2614 ATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNN 2672
ATA + + V+ TF AAR V+SDVET +V+ L+ +++ D+++T + NN
Sbjct 2678 ATARDCVKRGDDFQTVIKTFTDAARGPAGVESDVETSSIVDALQYAYKHDLQLTTEGFNN 2737
Query 2673 YMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSA 2732
Y+ +Y K +++ DLG ID +A +N ++ N A IWN D+M LS+ L++QIR A
Sbjct 2738 YVPSYIKPDSVATADLGCLIDLNAASVNQTSIRNANGACIWNSSDYMKLSDSLKRQIRIA 2797
Query 2733 AKKNNLPFKLTCATTRQVVNVVTTKIAL-KGGKIVNNWL--------KQLIKVTLVFLFV 2783
+K N+PF+LT + R N+++ K + K WL K VTLV +
Sbjct 2798 CRKCNIPFRLTTSRLRSADNILSVKFSATKLSGGAPKWLLKLRDFTWKSYCVVTLVVFAM 2857
Query 2784 AAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQR-G 2842
A + YL P MS+ + I+ YK ++ G+ RDI +DTCFANK+ F WF++ G
Sbjct 2858 AVLSYLCLPAFNMSQVSFHEDRILTYKVVENGIIRDITPSDTCFANKYQSFSKWFNEHYG 2917
Query 2843 GSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKL 2902
G + ND +CP+ AVI G VP LP + + F+ RVF++ N+CYTP+
Sbjct 2918 GLFNNDISCPVTVAVIAGVAGARVPNLPANVAWV-GRQIVLFVSRVFASSNNVCYTPTAE 2976
Query 2903 IEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-I 2961
I Y F+ S CVLA+ECT+F+DA GK PYCYD VL G+ AY+ ++P RY + D
Sbjct 2977 IPYERFSDSGCVLASECTLFRDAEGKINPYCYDPTVLPGASAYDQMKPHVRYDMYDSDMY 3036
Query 2962 IQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGV 3021
I+FP E ++R+ T + YCR G+CE + GVC++T+G W + ND+Y + PGV+CG
Sbjct 3037 IKFPEVVFESTLRITKTLATRYCRFGSCEDANEGVCITTNGSWAIYNDHYANKPGVYCGD 3096
Query 3022 DAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFN 3081
+ +++ + L QP+ +S S+ G ++ I +T YY + +RA +Y+
Sbjct 3097 NYFDIVRRLGLSLFQPVTYFQLSTSLALGVMLCIFLTIAFYYVNKVKRALADYTQCAVVA 3156
Query 3082 TLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWIT 3141
L++ LC L Y+ +Y Y TFYLT + +F+ H+ W VMF +VP W+
Sbjct 3157 VAAALLNSLCLCFVVSNPLLVLPYTALYYYATFYLTGEPAFVMHVSWFVMFGTVVPIWMV 3216
Query 3142 IAYIICISTKHFYWFFSNYLKRRV--VFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLL 3199
AYI+ + +H W + + K+ V +G +F++AA F++NK+ Y+ LR+ +
Sbjct 3217 FAYIVGVCLRHLLWVMAYFSKKHVEVFTDGKLNCSFQDAAANIFVINKDTYVALRNSI-- 3274
Query 3200 PLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITS 3259
YNRYL+++NKYKY+SGAMDT SYREA+ HL KAL +S +GSDVL+QPP S+TS
Sbjct 3275 TQDSYNRYLSMFNKYKYYSGAMDTASYREASAAHLCKALQVYSETGSDVLFQPPNCSVTS 3334
Query 3260 AVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYED 3319
+VLQSG KMA PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C ++ + +PNY+
Sbjct 3335 SVLQSGLVKMAAPSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDA 3394
Query 3320 LLIRKSNHNFLVQAG---NVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFS 3376
LL+ K+N +F+VQ LRV+GH+M +LKL V++ANP+TP Y F ++PG +FS
Sbjct 3395 LLVSKTNLSFIVQKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFS 3454
Query 3377 VLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHA 3436
VLACYNG P+GV+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H
Sbjct 3455 VLACYNGRPTGVFMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHT 3514
Query 3437 GTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLV 3496
G +G YG F DRQ Q +D T+N++AWLYAA++NG WF+ T + FN
Sbjct 3515 GCAFDGVMYGAFEDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEW 3574
Query 3497 AMKYNYE-PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFT 3555
AM + + VD+ L+ +TG++V + +++ L G G+TILG+++LEDEFT
Sbjct 3575 AMSNQFTEFIGTQSVDM---LAHKTGVSVEQLLYAIQTL-HKGFQGKTILGNSMLEDEFT 3630
Query 3556 PFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFA 3615
P DV Q GV QS VKR G HWL T+L + + +Q T+++++ +L+E L
Sbjct 3631 PDDVNMQVMGVVMQSGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLT 3690
Query 3616 MGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLDMVD 3671
++ + A M+ VKHKH FL LFLLP+ + Y N+VY P +S ++ + WL+
Sbjct 3691 PLVLCVMACVMLTVKHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPAS 3750
Query 3672 TSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAI 3731
+ D +Y S L ++ R + + L + + Y G+ +
Sbjct 3751 VYMRTTH-TDLGVYLSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPL 3808
Query 3732 SMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCT 3791
+ + ++TS+Y+ V + +A+ + Y P ++ ++L+Y +GYFCT
Sbjct 3809 TYLMFLTTLTSDYTVTVFLAVNVAKFFARVVFLYAPHAGFIFPEVKLVLLMYLAVGYFCT 3868
Query 3792 CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKP 3851
YFG+F LLN R+ LGVYDY VSTQEFRY+ GL P+NS +A +LN+KL+G+GG P
Sbjct 3869 VYFGVFSLLNLKLRVPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTP 3928
Query 3852 CIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKM 3911
CIK+A+VQSK++D+KCTSVVLLSVLQQL +E++SK WA CV+LHNDIL A D TEAF+
Sbjct 3929 CIKIASVQSKLTDLKCTSVVLLSVLQQLHLEANSKAWAHCVKLHNDILAATDPTEAFDNF 3988
Query 3912 VSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANG 3971
V L + L+S VD+ L ++LD+ + LQA SEFS L SYA AQ +Y++A+ +G
Sbjct 3989 VCLFATLMSFSANVDLEALASDLLDHPSVLQATLSEFSHLASYAELEAAQSSYQKALNSG 4048
Query 3972 D-SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQ 4030
D S VLK L+K++N+AK+ +++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQ
Sbjct 4049 DASPQVLKALQKAVNIAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQ 4108
Query 4031 TMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFT 4090
TMLF M++KLDND LN +I+NAR+GCVPL+++PL + KL VVIPD + + +
Sbjct 4109 TMLFGMIKKLDNDVLNGVISNARNGCVPLSVVPLCASNKLRVVIPDITIWNKVVTWPSLS 4168
Query 4091 YASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALR-ANSAVKLQNNELSPVAL 4149
YA ALW+I + + D ++V+ S+++ + + +L WPL++ R A+SAV LQNNE+ P L
Sbjct 4169 YAGALWDISLINNVDGEVVKSSDVT-ETNESLTWPLVLECTRAASSAVTLQNNEIRPSGL 4227
Query 4150 RQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTEL 4209
+ M +AG C + ++LAYY +G + ++ +LS+ LKWA+ DG + EL
Sbjct 4228 KTMVVSAGIDHANC-NTSSLAYYEPVEGRKMLMGILSENAHLKWAKVEGRDGF--VNIEL 4284
Query 4210 EPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSF 4269
+PPC+F+ PKGP+V+YLYF+K LNNL+RG +LG +AATVRLQAG+ TE NS+VLS
Sbjct 4285 QPPCKFLIAGPKGPEVRYLYFVKNLNNLHRGQLLGHIAATVRLQAGSNTEFAINSSVLSA 4344
Query 4270 CAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLY 4329
F+VD KAY D++ +GG P+TNCVKML TGTG A++V PEAN DQ+++GGAS CLY
Sbjct 4345 VTFSVDPGKAYLDFVNAGGAPLTNCVKMLTPKTGTGIAVSVKPEANADQDTYGGASVCLY 4404
Query 4330 CRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREP 4389
CR HI+HP+ G C KGK+VQ+P DPVGF L+NT C VC W G+GC+CD LR
Sbjct 4405 CRAHIEHPDVTGVCKFKGKFVQVPL-HIRDPVGFCLQNTPCNVCQFWIGHGCNCDALRGT 4463
Query 4390 MLQSADAQSFLNRVC 4404
+ + +FLN
Sbjct 4464 TIPQSKDSNFLNESG 4478
>sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus
HKU9 OX=694006 GN=1a PE=3 SV=1
Length=4248
Score = 4467 bits (11587), Expect = 0.0, Method: Composition-based stats.
Identities = 1586/4471 (35%), Positives = 2370/4471 (53%), Gaps = 349/4471 (8%)
Query 28 VRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV--LPQLEQPYVFIKRSDARTAPHG-HV 84
V G+ +EE L A+Q L+ LV V + P + V I S G
Sbjct 29 VTGWDIPIEEALEYAKQQLRTPEPQLVFVPYYLSHAPGISGDRVVITDSIWYATNFGWQP 88
Query 85 MVELVAELEGIQYGRSGETLGVLVPH------VGEIPVAYRKVLLRKNGNKGAGGHSYGA 138
+ EL + +G++YGR G T GVL+P +G+I + RK G G +S
Sbjct 89 IRELAMDKDGVRYGRGG-THGVLLPMQDPSFIMGDIDIQIRKY--------GIGANSPPD 139
Query 139 DLKSFDLGDELGTD--PYEDFQENW-NTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
L +D + G D PY DF +N TK + ++ D +G
Sbjct 140 VLPLWDGFSDPGPDVGPYLDFPDNCCPTKPKAKRGGDVYLS----------DQYGFDNNG 189
Query 196 YPLECIKDLLARAGKASCTLSEQLDFIDTKR--GVYCCREHEHEIAWYTERSEKSYELQT 253
+E + LL K+ TL + L + R Y + ++A R Q+
Sbjct 190 ILVEPVMKLLGVI-KSDFTLEQLLAALGKYRTEDGYDLPDGYVKVAIKVGRKAVPVLKQS 248
Query 254 PFEIKLAKKFDTFNGECPNFVFPLN--SIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNE 311
F + P + +P + S+++ +P + S+Y N
Sbjct 249 IFTV-----VGVTEQLVPGYYYPFSTSSVVEHTKPTRGGPVGKTVEAVMLSLYG---TNN 300
Query 312 CNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCP 371
N +KC +C W + CG E + ++C V+K P
Sbjct 301 YNPATPVARLKCSYCDYYGWTPLKDIGTVNCLCGAEF---QLTSSCVDAESAGVIK---P 354
Query 372 ACHNSEVGPEHSLAEYHNESGLKTILRKGGRT-IAFGGCVFSYVGCHNKCAYWVPRASAN 430
C + G++ I G RT ++FGG ++S +G N WVPRA +
Sbjct 355 GC----------VMLLDKSPGMRLI--PGNRTYVSFGGAIWSPIGKVNGVTVWVPRAYSI 402
Query 431 IGCNHTGVVGEG-SEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASFSASTSA--- 486
+ H+G VG G + +N L+E L + I + D N A +A+ T A
Sbjct 403 VAGEHSGAVGSGDTVAINKELVEYLIE---GIRVDADTLDNPTCATFIANLDCDTKAPVV 459
Query 487 -FVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVR 545
VE+++GL C K+ G E + L A+ + A
Sbjct 460 HTVESLQGL-----------CLANKIMLGDKP---LPTDEFHPFIVGL-AYHVQRACWYG 504
Query 546 SIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGV 605
++ SRT E ++ VR ++ +Q+ ++ + N V +AY TG V
Sbjct 505 ALASRTFEAFRDFVRTEEER-------FAQFFGKVCAPI--------NGCVYLAYTTGRV 549
Query 606 VQLTSQWLTN------------IFGTVYEKLKPVLDWLEEKFKEGVEFLRDGW----EIV 649
++ + N + V + LKP+L+W+ +K + + W E +
Sbjct 550 TLFSAYQVLNTAIAKSKDAFGGVAAIVVDMLKPILEWVLKK----MSIAKGAWLPYAEGL 605
Query 650 KFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETF 709
+ +V G+ + + L+ ++ S+ G K+ AL G +
Sbjct 606 LALFKAQFTVVKGKFQFLRASLNSKCHSLCDLLTTIMSKLLTSVKWAGCKVDALYTGTYY 665
Query 710 VTHSKGLYRKCVKSREETGLLM-PLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQ 768
KG+ + + GLL+ P + E+ L+G+ LT+ L+ + + +
Sbjct 666 YFSRKGVLTEVQLCAKRLGLLLTPKQQKMEVEVLDGDFDAPVTLTD---LELEECTGVLE 722
Query 769 PTSEAVEAPLV-GTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGD 827
A + LV GT V + + + +D Y + V F L+GG +KVTFGD
Sbjct 723 EVFGASDVKLVKGTLVSLASKLFVRTEDGFLY-RYVKSGGVLGKAFRLRGGGVSKVTFGD 781
Query 828 DTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQP-- 885
+ V + +VN ++++ E +D +L++ + + VE GT++ + ACVV AV + L
Sbjct 782 EEVHTIPNTVTVNFSYDVCEGLDAILDKVMAPFQVEEGTKLEDLACVVQKAVYERLSDLF 841
Query 886 --VSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYP--PDEDEEEGDCEEEEF 941
L P I+L+++ + +++ + E L MY S P +DE D E+
Sbjct 842 SDCPAELRP--INLEDFLTSECFVYSKDYEKILMPEMYFSLEDAVPVDDEMVDDIED--- 896
Query 942 EPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTT 1001
++ + ++ WL D +G+ED
Sbjct 897 --------------------------TVEQASDSDDQWLGD---------EGAEDCD--- 918
Query 1002 IQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAA 1061
TI +V M GY K+ ++VYIK ADIV+EA+ V+VNAA
Sbjct 919 -NTIQDVDVATSMTTP-----------CGYTKIAEHVYIKCADIVQEARNYSYAVLVNAA 966
Query 1062 NVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKH-CLHVVGP 1120
NV L HGGGVAGALN+ATNNAMQ ES +YI NG L+ GG +LS H LA H LHVVGP
Sbjct 967 NVNLHHGGGVAGALNRATNNAMQKESSEYIKANGSLQPGGHVLLSSHGLASHGILHVVGP 1026
Query 1121 NVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDK 1180
+ G+D+ LL + Y + + +L PL+SAGIFG SL V V Y+ V+D+
Sbjct 1027 DKRLGQDLALLDAVYAAYTGFDSVLTPLVSAGIFGFTVEESLCSLVKNVACTTYVVVYDR 1086
Query 1181 NLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDK--KIKACVEE 1238
LY++ +++ ++ + Q + I E E + S+ + + +
Sbjct 1087 QLYERALATSFDVPGPQSSVQHVPAIDWAEA----VEVQESIVDQVETPSLGAVDTVDSN 1142
Query 1239 VTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTA 1298
+ L ET EN++ + PD + D V D+V++ V
Sbjct 1143 ADSGLNETARSPENVVGSV-------PDD-----------VVADVESCVRDLVRQVV--- 1181
Query 1299 VVIPTKKAGGTTEMLAKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPS 1358
+KV D P + TVE+ + +L
Sbjct 1182 -------------------KKVKRDK----RPPPIVPQQTVEQQPQEISSPGDCNTVLVD 1218
Query 1359 IISNEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDY 1418
+ VS + M+ +E L+PV ++ A + ++R +EG+
Sbjct 1219 V-----------VSMSFSAMVNFGKEKGLLIPVVIDYPAFLKVLKR----FSPKEGLFSS 1263
Query 1419 -GARFYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSV 1477
G FY Y+ + + LN L L+ +P G++ +G L +A MR L VP TV V
Sbjct 1264 NGYEFYGYSRDKPLHEVSKDLNSLGRPLIMIPFGFIVNGQTLAVSAVSMRGLTVPHTVVV 1323
Query 1478 SSPDAVTAYNGYLT---SSSKTPEEHFIETISLAGSYKDWSYSGQSTQLGIE----FLKR 1530
S +V Y Y S T + F+ I L G+ +DW + + + KR
Sbjct 1324 PSESSVPLYRAYFNGVFSGDTTAVQDFVVDILLNGA-RDWDVLQTTCTVDRKVYKTICKR 1382
Query 1531 GDKSVYYTSNPTTFHLDGEV-ITFDNLKTLLSLREVRT------IKVFTTVDNINLHTQV 1583
G+ + + + + + G+V + F + + E + IKV TTVD IN T +
Sbjct 1383 GNTYLCF-DDTNLYAITGDVVLKFATVSKARAYLETKLCAPEPLIKVLTTVDGINYSTVL 1441
Query 1584 VDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAF-EYYHTTDPSF 1642
V + +Y Q G + DG D + P + EG Y N + V A EYY D +
Sbjct 1442 VSTAQSYRAQIGTVFCDGHDWSNKNPMPTDEGTHLYKQDNFSSAEVTAIREYYGVDDSNI 1501
Query 1643 LGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRA 1702
+ R MS + W Y V+G + D+NCYL A+ LQ I++ F+ P + AY
Sbjct 1502 IARAMSIRKTVQTWPYTVVDGRVLLAQRDSNCYLNVAISLLQDIDVSFSTPWVCRAYDAL 1561
Query 1703 RAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTL 1762
+ G +++A T G D +S + H + + +RV+ VC+ CG Q
Sbjct 1562 KGGNPLPMAEVLIALGKATPGVSDDAHMVLSAVLNHGTV-TARRVMQTVCEHCGVSQMVF 1620
Query 1763 KGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYEL-KHGTF 1821
G +A + G++ + V + C CG+ A +Y+ +Q+SP+++MS P Q L G +
Sbjct 1621 TGTDACTFYGSVVLDDLYAPVSVVCQCGRPAIRYVSEQKSPWLLMSCTPTQVPLDTSGIW 1680
Query 1822 TCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVT 1881
A + G GHY + + + D ++S+ K P TD+ Y S+T+ K T
Sbjct 1681 KTAIVFRGPVTAGHYMYAVNGTLISVYDANTRRRTSDLKLPATDILYGPTSFTSDSKVET 1740
Query 1882 YKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPNASFDNFKFV-CDNIKFADD 1940
Y LDGV T IDP Y K+ + YFT PI++V P S+D F C N + A+
Sbjct 1741 YYLDGVKRTTIDPDFSKYVKRGDYYFTTAPIEVV-AAPKLVTSYDGFYLSSCQNPQLAES 1799
Query 1941 LNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNK 2000
N+ K +L +T +P++ GDVVAI + G+ + KP+++
Sbjct 1800 FNKAINATKTGPMKL-LTMYPNVAGDVVAISDDNVVA-HPYGSLHMGKPVLF-------- 1849
Query 2001 ATYKPNTWC-IRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENP-TIQ 2058
+PNTW + L ST V T N++DVL D PV+ E E P +++
Sbjct 1850 -VTRPNTWKKLVPLLSTVVVNTPNTYDVLAV------------DPLPVNNETSEEPISVK 1896
Query 2059 KDVLECNVKTTEVVGDIILKPANNS-LKITEEVGHTDLMAAYVDN-SSLTIKKPNELSRV 2116
+ +K T V+ P N L +E TDL YV+ + K + LS+V
Sbjct 1897 APIPLYGLKATMVLNGTTYVPGNKGHLLCLKEFTLTDLQTFYVEGVQPFVLLKASHLSKV 1956
Query 2117 LGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT--NIVTRCLNRV---------- 2164
LGL+ + VN + + YA L V+T+ +VTR + +
Sbjct 1957 LGLRV--SDSSLHVNHLSKGVVYAYAATRLTTRVTTSLLGGLVTRSVRKTADFVRSTNPG 2014
Query 2165 --CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPN 2222
C + F+ L ++ + +K S IA NT V L + + +
Sbjct 2015 SKCVGLLCLFYQLFMRFWLLVKKP-PIVKVS--GIIAYNTGCGVTTCVLNYLRSRCGNIS 2071
Query 2223 FSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYRE--GYLNSTNVTIAT 2280
+S+L+ ++ + L + L GV +S PS T ++ G + + +
Sbjct 2072 WSRLLKLLRYMLYIWFVWTCLT----ICGVWLSEPYAPSLVTRFKYFLGIVMPCDYVLVN 2127
Query 2281 YCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYV 2340
+C++G+DSLD YP+L Q S ++ T ++ E F AY+L+T +
Sbjct 2128 ETGTGWLHHLCMAGMDSLD-YPALRMQQHRYGSP-YNYTYILMLLEAFFAYLLYTPALPI 2185
Query 2341 LGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
+G+ A++ L Y + + NSWL+ + ++++ P ++M+RMYI A + +K ++HV
Sbjct 2186 VGILAVLHLIVLYLPIP-LGNSWLVVFLYYIIRLVPFTSMLRMYIVIAFLWLCYKGFLHV 2244
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GCN+ C+MCYK+N A R+EC+T+VNGV+R FYV ANGG FC HNWNCV+CDT+
Sbjct 2245 RYGCNNVACLMCYKKNVAKRIECSTVVNGVKRMFYVNANGGTHFCTKHNWNCVSCDTYTV 2304
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
STFI +VA DLS QFKRPI TD++ Y V SV V+NG ++ YF+ GQ++YER +
Sbjct 2305 DSTFICRQVALDLSAQFKRPIIHTDEAYYEVTSVEVRNGYVYCYFESDGQRSYERFPMDA 2364
Query 2521 FVNLDNLRANNTKGSLP-INVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSD 2579
F N+ L + KG+ P NV+VFD ++ EE++ K+A++YY+QL C+PILL+D+ +V
Sbjct 2365 FTNVSKLHYSELKGAAPAFNVLVFDATNRIEENAVKTAAIYYAQLACKPILLVDKRMVGV 2424
Query 2580 VGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQ 2639
VGD A +A MF+AY + +++ M+K+K L +TA +++ +++++VL F+ + R
Sbjct 2425 VGDDATIARAMFEAYAQNYLLKYSIAMDKVKHLYSTALQQISSGMTVESVLKVFVGSTRA 2484
Query 2640 GFVD--SDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSAR 2697
D SDV+T D+V C++L HQ E T DS NN + TY K + ++ ++G + +A+
Sbjct 2485 EAKDLESDVDTNDLVSCIRLCHQEGWEWTTDSWNNLVPTYIKQDTLSTLEVGQFMTANAK 2544
Query 2698 HINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTK 2757
++NA +AK + LIW DF+ LSE +R+Q++ AA+K L +T ++ + V + T
Sbjct 2545 YVNANIAKGAAVNLIWRYADFIKLSESMRRQLKVAARKTGLNLLVTTSSLKADVPCMVTP 2604
Query 2758 IALKGG-KIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGV 2816
+ GG + + +W + LI V ++ + + ++ TP ++M ++ +K ID V
Sbjct 2605 FKIIGGHRRIVSWRRVLIHVFMLLVVLNPQWF--TPWYIMRP---IEYNVVDFKVIDNAV 2659
Query 2817 TRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRT 2876
RDI S D CFANK + F+ W+S R GSY N + CP++ V++ VG +VPGLP LR
Sbjct 2660 IRDITSADQCFANKFSAFENWYSNRYGSYVNSRGCPMVVGVVSDIVGSLVPGLPARFLRV 2719
Query 2877 TNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDT 2936
L + AVG++CYTP I Y F TSACVLAA CT+F ASG+ +PYC D
Sbjct 2720 GT-TLLPLVNYGLGAVGSVCYTPHYAINYDVFDTSACVLAATCTLFSSASGERMPYCADA 2778
Query 2937 NVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAG 2995
+++ + Y+ L+P Y + S I+FP V +V T EYC+ G C+ SEAG
Sbjct 2779 ALIQNASRYDMLKPHVMYPFYEHSGYIRFPEVIS-AGVHIVRTMAMEYCKVGRCDVSEAG 2837
Query 2996 VCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAI 3055
+C+S RWV+NN Y+R GV+CG A +L NM P+ P+GA+DI+ SI+ G ++A+
Sbjct 2838 LCMSLQPRWVVNNAYFRQQSGVYCGTSAFDLFMNMLLPIFTPVGAVDITTSILMGALLAV 2897
Query 3056 VVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFY 3115
VV+ YY +RFRRAFG+YS V+ N L F+++ VLCL Y LP +Y++++LY T Y
Sbjct 2898 VVSMSLYYLLRFRRAFGDYSGVIFTNILAFVLNVIVLCLEGPYPMLPSIYAMVFLYATCY 2957
Query 3116 LTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTF 3175
+D++ + H+ +++MF +VP W+T+ YI+ + ++H WF S KR V ++F +F
Sbjct 2958 FGSDIACMMHVSFLIMFAGVVPLWVTVLYIVVVLSRHILWFASLCTKRTVQVGDLAFHSF 3017
Query 3176 EEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLA 3235
++AAL TF+L+KE++L+L+ ++ Y +YLA+YNKYKY+SG MDT +YREAAC HL
Sbjct 3018 QDAALQTFMLDKEVFLRLKREI--SSDAYFKYLAMYNKYKYYSGPMDTAAYREAACSHLV 3075
Query 3236 KALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
AL +SN G D +YQPP+ S+ SA LQ+G +MA PSG VE C+V+V G+ TLNG+WL
Sbjct 3076 MALEKYSNGGGDTIYQPPRCSVASAALQAGLTRMAHPSGLVEPCLVKVNYGSMTLNGIWL 3135
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVD 3355
D+ V CPRHV+C+ +++ NP+Y L +R +N++F V +RVIGH+M+ +LKL VD
Sbjct 3136 DNFVICPRHVMCSRDELANPDYPRLSMRAANYDFHVSQNGHNIRVIGHTMEGSLLKLTVD 3195
Query 3356 TANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNI 3415
NPKTP Y F+R+ GQ S+LACY+G P+GVY C +R N T++ SFL GSCGS GF +
Sbjct 3196 VNNPKTPAYSFIRVSTGQAMSLLACYDGLPTGVYTCTLRSNGTMRASFLCGSCGSPGFVM 3255
Query 3416 DYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAV 3475
+ V FCY+H +ELP G H GTD G FYGPF D+Q Q A D TITVNVLAWLYAAV
Sbjct 3256 NGKEVQFCYLHQLELPNGTHTGTDFSGVFYGPFEDKQVPQLAAPDCTITVNVLAWLYAAV 3315
Query 3476 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL 3535
++G+ WFL + + + +FN A+KY + +T + + +L PL+A+TGI+V M ++LK LL
Sbjct 3316 LSGENWFLTKSSISPAEFNNCAVKYMCQSVTSESLQVLQPLAAKTGISVERMLSALKVLL 3375
Query 3536 QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLV 3595
G GRTI+GS LEDE TP+D+ RQ GV Q + + T W + + ++L+L+
Sbjct 3376 SAGFCGRTIMGSCSLEDEHTPYDIGRQMLGVKLQGKFQSMFRWTLQWFAIIFVLTILILL 3435
Query 3596 QSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYM 3655
Q QW+ L LP + F + +KHKH +L ++LLP AY+N Y
Sbjct 3436 QLAQWTFVGALPFTLLLPLIGFVAVCVGFVSLLIKHKHTYLTVYLLPVAMVTAYYNFQYT 3495
Query 3656 PASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVL 3715
P +++ + V+ D + V L++ R V D R+W + +
Sbjct 3496 PEGVQGYLLSLYNYVNPGRIDVIGTDLLTMLIISVACTLLSVRMVRTDAYSRIWYVCTAV 3555
Query 3716 TLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNT 3775
+Y + G+A AIS ++SV +NY+GV ++ A+ +V++ P +
Sbjct 3556 GWLYNCWTGSADTVAISYLTFMVSVFTNYTGVACASLYAAQFMVWVLKFLDPTILLLYGR 3615
Query 3776 LQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSI 3835
+C+++ Y +GY CTCYFG+F L+NR FR TLG Y+Y+VS+QE RYMNS GLLPP NS
Sbjct 3616 FRCVLVCYLLVGYLCTCYFGVFNLINRLFRCTLGNYEYVVSSQELRYMNSHGLLPPTNSW 3675
Query 3836 DAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLH 3895
A LNIKL G+GG P +V+T+QS M+D+KCTSVVLLSVLQQLRVESSSKLWA CV+LH
Sbjct 3676 QALMLNIKLAGIGGIPIYRVSTIQSNMTDLKCTSVVLLSVLQQLRVESSSKLWALCVKLH 3735
Query 3896 NDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYA 3955
N+IL + TEAFE VSLLSVLLS+ GA+++++LC +L+N + LQA+ASEFS+L SY
Sbjct 3736 NEILASNSPTEAFEAFVSLLSVLLSLPGAINLDELCSSILENNSVLQAVASEFSNLSSYV 3795
Query 3956 AFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQ 4015
+ AQ+AY+ AVA G + LKK++NVAKS D+D A RKLE+M++ AMT MYKQ
Sbjct 3796 DYENAQKAYDTAVATGAPASTVNALKKAMNVAKSVLDKDVATTRKLERMSELAMTAMYKQ 3855
Query 4016 ARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIP 4075
AR+ED+R+KVT+AMQTMLF M+R+LD+DAL+NI+NNAR+G VPL +IP T A KL++V+P
Sbjct 3856 ARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILNNARNGVVPLGVIPRTAANKLLLVVP 3915
Query 4076 DYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALR--A 4133
D++ Y T T TYA + W++ QV DAD K V ++I+ +NS NLAWPL+VTA R A
Sbjct 3916 DFSVYTATITMPTLTYAGSAWDVMQVADADGKTVNATDITRENSVNLAWPLVVTAQRQQA 3975
Query 4134 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKW 4193
S VKLQNNEL P +++M+ AG +QTAC D A+AYYN TK GR V+A+L+D L +
Sbjct 3976 TSPVKLQNNELMPQTVKRMNVVAGVSQTACVTD-AVAYYNATKEGRHVMAILADTDGLAF 4034
Query 4194 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4253
A+ KS G G + ELEPPC+F+ DTPKGP +KYLYF KGL NL RG VLG+LA TVRL
Sbjct 4035 AKVEKSTGDGFVILELEPPCKFMVDTPKGPALKYLYFTKGLKNLCRGTVLGTLACTVRLH 4094
Query 4254 AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
AG+ATEV +NS++LS C+F+VD YKDYL +GG PI NCVKML HTGTG AIT P+
Sbjct 4095 AGSATEVASNSSILSLCSFSVDPEATYKDYLDNGGSPIGNCVKMLTPHTGTGLAITAKPD 4154
Query 4314 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVC 4373
AN+DQESFGGASCCLYCRCHI+HP G C KGK+VQIP NDP+GF ++N VC VC
Sbjct 4155 ANIDQESFGGASCCLYCRCHIEHPGASGVCKYKGKFVQIPLVGVNDPIGFCIRNVVCAVC 4214
Query 4374 GMWKGYGCSCDQLREPMLQSADAQSFLNRVC 4404
MW+GYGC C LRE LQ+ D + FLN
Sbjct 4215 NMWQGYGCPCSSLREINLQARD-ECFLNESG 4244
>sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respiratory
syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=1a PE=1 SV=1
Length=4391
Score = 3835 bits (9946), Expect = 0.0, Method: Composition-based stats.
Identities = 1245/3390 (37%), Positives = 1879/3390 (55%), Gaps = 176/3390 (5%)
Query 1156 ADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPF- 1214
+V + + + ++V E ++ + +++A + + + +
Sbjct 1034 VPVEDIAQVVIADTLQETPVVSDTVEVPPQVVKLPSEPQTIQPEVKEVAPVYEADTEQTQ 1093
Query 1215 -ITESKPSVEQRKQDDK----KIKACVEEVT----TTLEETKFLTENLLLYI-------- 1257
+T + +++ D + K E VT ++ K E++L+
Sbjct 1094 SVTVKPKRLRKKRNVDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHG 1153
Query 1258 -DINGNLHPDSATLVSDIDITFLKKDAPYIVGD-VVQEGVLTA-----VVIPTKKAGGTT 1310
I G ++ S V ++ P VGD V+ +G A VV P +A
Sbjct 1154 GGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDV 1213
Query 1311 EMLAK---ALRKVPTDNYITTYPGQGLNG--------YTVEEAKTVLKKCKSAFYILPSI 1359
+L+K A+ P +T G+ G Y + EAKT + ++ + S+
Sbjct 1214 SLLSKCYKAMNAYPL--VVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSL 1271
Query 1360 ISNEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYG 1419
+ + L LR + A++ + VC + A ++ K + VD G
Sbjct 1272 TIVDIPQSLTFSYDGLRGAIRKAKDYGFTVFVCTDNSANTKVLRNKGVDYTKKFLTVD-G 1330
Query 1420 ARFYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSS 1479
++Y YTSK T+ ++ N + +++MPLGYV+HGL+L +A +R + VP +++
Sbjct 1331 VQYYCYTSKDTLDDILQQANK-SVGIISMPLGYVSHGLDLIQAGSVVRRVNVPYVCLLAN 1389
Query 1480 PDAVTAYNGYLTSSSK--TPEEHFIETISLAGSYKDWSYSG-----QSTQLGIEFLKRGD 1532
+ L S P E FI+ + G Y W Q +L + L D
Sbjct 1390 KEQ----EAILMSEDVKLNPSEDFIKHVRTNGGYNSWHLVEGELLVQDLRLN-KLLHWSD 1444
Query 1533 KSVYYTSNPTTFHLDGEVITFDNLKTLLSLREVRT-----IKVFTTVDNINLHTQVVDMS 1587
+++ Y + + F+ L + + RT I+V TVD +N T V++
Sbjct 1445 QTICYKDSVFYVVKNSTAFPFETLSACRAYLDSRTTQQLTIEVLVTVDGVNFRTVVLNNK 1504
Query 1588 MTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAF-EYYHTTDPSFLGRY 1646
TY Q G + +GAD++ P G + Y+ N +A E Y DP+FL R+
Sbjct 1505 NTYRSQLGCVFFNGADISDTIPDEKQNGHSLYLADNLTADETKALKELYGPVDPTFLHRF 1564
Query 1647 MSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQI-ELKFNPPALQDAYYRARAG 1705
S KWK + + S+K +DNNCYL ++TL + ++KF PALQ A+ + + G
Sbjct 1565 YSLKAAVHKWKMVVCDKVRSLKLSDNNCYLNAVIMTLDLLKDIKFVIPALQHAFMKHKGG 1624
Query 1706 EAANFCALILAYCNKTVGELGDVRETMSYLFQHANLD-SCKRVLNVVCKTCGQQQTTLKG 1764
++ +F ALI+AY N T G D + + A L S + V C CG + L+G
Sbjct 1625 DSTDFIALIMAYGNCTFGAPDDASRLLHTVLAKAELCCSARMVWREWCNVCGIKDVVLQG 1684
Query 1765 VEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGT---F 1821
++A Y+G + E + + C CG + + +V+ +P++++S P + + T F
Sbjct 1685 LKACCYVGVQTVEDLRARMTYVCQCGGERHRQIVEHTTPWLLLSGTPNEKLVTTSTAPDF 1744
Query 1822 TCASEYTG-NYQCGHYKHITSKETLYC-IDGALLTKSSEYKGPITDVFYKENSYTTTIKP 1879
+ + G GHY H K L D ++K+S++K +TDV + Y++
Sbjct 1745 VAFNVFQGIETAVGHYVHARLKGGLILKFDSGTVSKTSDWKCKVTDVLFPGQKYSSDCNV 1804
Query 1880 VTYKLDGVVCTEIDPKLDNYYKKDNSYFT-EQPIDLVPNQPYPNASFDNFKFVCDNIKFA 1938
V Y LDG TE+DP L +Y KD YFT E P+ P + + N V + +
Sbjct 1805 VRYSLDGNFRTEVDPDLSAFYVKDGKYFTSEPPVTYSPATILAGSVYTNSCLVSSDGQPG 1864
Query 1939 DD-----LNQLTGYK--KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIV 1991
D N L G+ KP +++ +F P +GDV+ ++ Y P +K GA KPI+
Sbjct 1865 GDAISLSFNNLLGFDSSKPVTKKYTYSFLPKEDGDVLLAEFDTYDPIYKNGAMYKGKPIL 1924
Query 1992 WHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEV 2051
W + + K N +R ++ P+E N F L E PV
Sbjct 1925 WVNKASYDTNLNKFNRASLRQIFDVAPIELENKFTPLSVEST------------PVEPPT 1972
Query 2052 VENPTIQKD--VLECNVKTTEVVGDII-LKPANNSLKITEEVGHTDLMAAYVD-NSSLTI 2107
V+ +Q++ +++C V D + ++ + E + DL YVD + +
Sbjct 1973 VDVVALQQEMTIVKCKGLNKPFVKDNVSFVADDSGTPVVEYLSKEDLHTLYVDPKYQVIV 2032
Query 2108 KKPNELSRVLGLKTLATHGLAAV---NSVPWDTIANYAKPFLNK----VVSTTTNIVTRC 2160
K N LS +L L T+ + + V S+ + F K T T V C
Sbjct 2033 LKDNVLSSMLRLHTVESGDINVVAASGSLTRKVKLLFRASFYFKEFATRTFTATTAVGSC 2092
Query 2161 LNRV-------------CTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTT---IAKNTVK 2204
+ V C +++ F L L + ++ + +K S T + N VK
Sbjct 2093 IKSVVRHLGVTKGILTGCFSFVKMLFMLPLAYFSDSKLGTTEVKVSALKTAGVVTGNVVK 2152
Query 2205 SVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMS--------- 2255
++ S + L+ ++ + +++ V L S+ + VL S
Sbjct 2153 QCCTAAVDLSMDKLRRVDWKSTLRLLLMLCTTMVLLSSVYHLYVFNQVLSSDVMFEDAQG 2212
Query 2256 ----------NLGMPSYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDSLDTYPSL 2304
LG+ S C G Y + + + T+C S C+ CL DS+ YP+L
Sbjct 2213 LKKFYKEVRAYLGISSACDGLASAYR-ANSFDVPTFCANRSAMCNWCLISQDSITHYPAL 2271
Query 2305 ETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVH--FISNS 2362
+ +Q +S + ++ E LAY+L+T F L LA + FF+ ++ + S +
Sbjct 2272 KMVQTHLSHYVLNIDWLWFAFETGLAYMLYTSAFNWLLLAGTLHYFFAQTSIFVDWRSYN 2331
Query 2363 WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVE 2422
+ + L P++ +VRMY A + + K Y HV++GC + C++CYKRNR TRVE
Sbjct 2332 YAVSSAFWLFTHIPMAGLVRMYNLLACLWLLRKFYQHVINGCKDTACLLCYKRNRLTRVE 2391
Query 2423 CTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPIN 2482
+T+V G +R+FY+ ANGG FC+ HNWNCV+CDT G+TFI +EVA DL+ +RPIN
Sbjct 2392 ASTVVCGGKRTFYITANGGISFCRRHNWNCVDCDTAGVGNTFICEEVANDLTTALRRPIN 2451
Query 2483 PTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANN----TKGSLPI 2538
TD+S Y VDSVTVK + + + GQ YER L F NLD L+ T G
Sbjct 2452 ATDRSHYYVDSVTVKETVVQFNYRRDGQPFYERFPLCAFTNLDKLKFKEVCKTTTGIPEY 2511
Query 2539 NVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTF 2598
N I++D + +ES A+SA VYYSQ++C+ ILL+D +LV+ VGDS+E+A KMFD++VN+F
Sbjct 2512 NFIIYDSSDRGQESLARSACVYYSQVLCKSILLVDSSLVTSVGDSSEIATKMFDSFVNSF 2571
Query 2599 SSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDVETKDVVECLKL 2657
S +NV +KL+ L++TA + + + +VL+TFI AAR V+SDVET ++V+ ++
Sbjct 2572 VSLYNVTRDKLEKLISTARDGVRRGDNFHSVLTTFIDAARGPAGVESDVETNEIVDSVQY 2631
Query 2658 SHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKD 2717
+H+ DI++T +S NNY+ +Y K ++++ DLG+ IDC+A +N V ++ N A IWN
Sbjct 2632 AHKHDIQITNESYNNYVPSYVKPDSVSTSDLGSLIDCNAASVNQIVLRNSNGACIWNAAA 2691
Query 2718 FMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKI-ALKGGKIVNNWL------ 2770
+M LS+ L++QIR A +K NL F+LT + R N+++ + A K W
Sbjct 2692 YMKLSDALKRQIRIACRKCNLAFRLTTSKLRANDNILSVRFTANKIVGGAPTWFNALRDF 2751
Query 2771 --KQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFA 2828
K + T++ A + YL P M + I+ +K +D G+ RD+ D CFA
Sbjct 2752 TLKGYVLATIIVFLCAVLMYLCLPTFSMVPVEFYEDRILDFKVLDNGIIRDVNPDDKCFA 2811
Query 2829 NKHADFDTWFSQR-GGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPR 2887
NKH F W+ + GG Y N CPL AVI G +P +P T+ N + F+ R
Sbjct 2812 NKHRSFTQWYHEHVGGVYDNSITCPLTVAVIAGVAGARIPDVPTTLAWV-NNQIIFFVSR 2870
Query 2888 VFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYES 2947
VF+ G++CYTP I Y F+ S C+L +ECT+F+DA G+ PYC+D VL G+ AY
Sbjct 2871 VFANTGSVCYTPIDEIPYKSFSDSGCILPSECTMFRDAEGRMTPYCHDPTVLPGAFAYSQ 2930
Query 2948 LRPDTRYVLMDGSI-IQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVL 3006
+RP RY L DG++ I+FP E ++R+ T ++YCR G+CE ++ GVC++T+G W +
Sbjct 2931 MRPHVRYDLYDGNMFIKFPEVVFESTLRITRTLSTQYCRFGSCEYAQEGVCITTNGSWAI 2990
Query 3007 NNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMR 3066
ND++ + PGV+CG D ++++ + L QPI ++ S+V G + +T L YY +
Sbjct 2991 FNDHHLNRPGVYCGSDFIDIVRRLAVSLFQPITYFQLTTSLVLGIGLCAFLTLLFYYINK 3050
Query 3067 FRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHI 3126
+RAF +Y+ + +++ +C Y+ +Y Y TFY TN+ +F+ H+
Sbjct 3051 VKRAFADYTQCAVIAVVAAVLNSLCICFVASIPLCIVPYTALYYYATFYFTNEPAFIMHV 3110
Query 3127 QWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV--VFNGVSFSTFEEAALCTFL 3184
W +MF P+VP W+T Y + + +HF+W + + K+ V +G +F++AA F+
Sbjct 3111 SWYIMFGPIVPIWMTCVYTVAMCFRHFFWVLAYFSKKHVEVFTDGKLNCSFQDAASNIFV 3170
Query 3185 LNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNS 3244
+NK+ Y LR+ L Y+R+L L+NKYKYFSGAM+T +YREAA CHLAKAL +S +
Sbjct 3171 INKDTYAALRNS--LTNDAYSRFLGLFNKYKYFSGAMETAAYREAAACHLAKALQTYSET 3228
Query 3245 GSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRH 3304
GSD+LYQPP SITS VLQSG KM+ PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRH
Sbjct 3229 GSDLLYQPPNCSITSGVLQSGLVKMSHPSGDVEACMVQVTCGSMTLNGLWLDNTVWCPRH 3288
Query 3305 VICTSEDMLNPNYEDLLIRKSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKT 3361
V+C ++ + +PNY+ LLI +NH+F VQ LRV+GH+MQ +LKL VD ANP T
Sbjct 3289 VMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVVGHAMQGTLLKLTVDVANPST 3348
Query 3362 PKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVS 3421
P Y F ++PG FSVLACYNG P+G + MRPN+TIKGSFL GSCGSVG+ + ++
Sbjct 3349 PAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCGSCGSVGYTKEGSVIN 3408
Query 3422 FCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRW 3481
FCYMH MEL G H G+ +G YG F+D+Q Q TD +VNV+AWLYAA++NG W
Sbjct 3409 FCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVNVVAWLYAAILNGCAW 3468
Query 3482 FLNRFTTTLNDFNLVAMKYNYE-PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMN 3540
F+ T++ FN A+ + + VD+ L+ +TG+A+ + ++++L G
Sbjct 3469 FVKPNRTSVVSFNEWALANQFTEFVGTQSVDM---LAVKTGVAIEQLLYAIQQLY-TGFQ 3524
Query 3541 GRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQW 3600
G+ ILGS +LEDEFTP DV Q GV QS V++ GT HWL T++++ ++++Q+T++
Sbjct 3525 GKQILGSTMLEDEFTPEDVNMQIMGVVMQSGVRKVTYGTAHWLFATLVSTYVIILQATKF 3584
Query 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP---- 3656
+L+ +L+E + AF M+ VKHKH FL LFLLP + Y N+VY P
Sbjct 3585 TLWNYLFETIPTQLFPLLFVTMAFVMLLVKHKHTFLTLFLLPVAICLTYANIVYEPTTPI 3644
Query 3657 ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLT 3716
+S ++ + WL + + D +Y S ++L+++ R + L + +
Sbjct 3645 SSALIAVANWLAPTNAYMRTTH-TDIGVYISMSLVLVIVVKRLYNPSLSNFALALCSGVM 3703
Query 3717 LVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTL 3776
+Y G A I+ + ++TS+Y+ V + LA+ + Y P + +
Sbjct 3704 WLYTYSIGEA-SSPIAYLVFVTTLTSDYTITVFVTVNLAKVCTYAIFAYSPQLTLVFPEV 3762
Query 3777 QCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSID 3836
+ I+L+Y LG+ CTCYFG+F LLN R +GVYD+ VSTQEFR+M + L P+NS +
Sbjct 3763 KMILLLYTCLGFMCTCYFGVFSLLNLKLRAPMGVYDFKVSTQEFRFMTANNLTAPRNSWE 3822
Query 3837 AFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHN 3896
A LN KL+G+GG PCIKVA +QSK++D+KCTSVVLLSVLQQL +E++S+ WA CV+ HN
Sbjct 3823 AMALNFKLIGIGGTPCIKVAAMQSKLTDLKCTSVVLLSVLQQLHLEANSRAWAFCVKCHN 3882
Query 3897 DILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA 3956
DIL A D +EAFEK VSL + L++ G VD++ L ++ D + LQA SEFS L ++A
Sbjct 3883 DILAATDPSEAFEKFVSLFATLMTFSGNVDLDALASDIFDTPSVLQATLSEFSHLATFAE 3942
Query 3957 FATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQ 4015
AQ+AY++A+ +GD S VLK L+K++N+AK+ +++D A+ RKLE+MADQAMT MYKQ
Sbjct 3943 LEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKNAYEKDKAVARKLERMADQAMTSMYKQ 4002
Query 4016 ARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIP 4075
AR+EDK+AK+ SAMQTMLF M++KLDND LN II+NAR+GC+PL++IPL + KL VVIP
Sbjct 4003 ARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIPLSVIPLCASNKLRVVIP 4062
Query 4076 DYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRAN- 4134
D+ + + YA ALW+I + + D++IV+ S++ +D++ NL WPL++ RA+
Sbjct 4063 DFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDV-VDSNENLTWPLVLECTRAST 4121
Query 4135 SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
SAVKLQNNE+ P L+ M +AG QT C + ++LAYY +G + ++ALLSD LKWA
Sbjct 4122 SAVKLQNNEIKPSGLKTMVVSAGQEQTNC-NTSSLAYYEPVQGRKMLMALLSDNAYLKWA 4180
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
R DG ++ EL+PPC+F+ PKGP+++YLYF+K LNNL+RG VLG +AATVRLQA
Sbjct 4181 RVEGKDGFVSV--ELQPPCKFLIAGPKGPEIRYLYFVKNLNNLHRGQVLGHIAATVRLQA 4238
Query 4255 GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEA 4314
G+ TE +NS+VLS F VD KAY D++ +GG P+TNCVKML TGTG AI+V PE+
Sbjct 4239 GSNTEFASNSSVLSLVNFTVDPQKAYLDFVNAGGAPLTNCVKMLTPKTGTGIAISVKPES 4298
Query 4315 NMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCG 4374
DQE++GGAS CLYCR HI+HP+ G C KGK+VQIP C DPVGF L NT C VC
Sbjct 4299 TADQETYGGASVCLYCRAHIEHPDVSGVCKYKGKFVQIPAQCVRDPVGFCLSNTPCNVCQ 4358
Query 4375 MWKGYGCSCDQLREPMLQSADAQSFLNRVC 4404
W GYGC+CD LR+ L + +FLN
Sbjct 4359 YWIGYGCNCDSLRQAALPQSKDSNFLNESG 4388
Score = 938 bits (2424), Expect = 0.0, Method: Composition-based stats.
Identities = 298/1276 (23%), Positives = 527/1276 (41%), Gaps = 130/1276 (10%)
Query 11 KTHVQLSLPVLQVRDV---LVRGFGDSVEEVLSEARQHLKDGTCGLVEVEK--GVLPQLE 65
+ HV L++P+ ++ L F D E + L L + G L
Sbjct 26 QDHVSLTVPLCGSGNLVEKLSPWFMDG-ENAYEVVKAMLLKKEPLLYVPIRLAGHTRHLP 84
Query 66 QPYVFIKRSDARTAPHGHVMVELVAELEG-----IQYGRSGETLGVLVPHVGEIPVAYRK 120
P V++ MV +A + G+ +G+ P+ E+ +
Sbjct 85 GPRVYLVERLIACEN--PFMVNQLAYSSSANGSLVGTTLQGKPIGMFFPYDIELVTGKQN 142
Query 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
+LLRK G GG+ Y ++ + + +DF+ + K+ + L+++L GG
Sbjct 143 ILLRKYGR---GGYHYTP--FHYERDNTSCPEWMDDFEADPKGKY----AQNLLKKLIGG 193
Query 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCT-LSEQLDFIDTKRGVYCCREHEHEIA 239
T VD CG DG P+ L+A+ G + + G + + + +
Sbjct 194 DVTP-VDQYMCGVDGKPISAYAFLMAKDGITKLADVEADVAARADDEGFITLKNNLYRLV 252
Query 240 WYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGR 299
W+ ER + Y Q+ F I + D P F L I T+ PR + + +
Sbjct 253 WHVERKDVPYPKQSIFTINSVVQKDGVENTPP-HYFTLGCKILTLTPRNKWSGVSDLSLK 311
Query 300 IRSVYPVAS---PNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKE-GAT 355
+ +Y + S ++C CG SW TG+ ++ CG +
Sbjct 312 QKLLYTFYGKESLENPTYIYHSAFIECGSCGNDSWLTGNAIQGFACGCGASYTANDVEVQ 371
Query 356 TCGYLPQNAVVKIYCPACHNSEVG--PEHSLAEYHNESG--LKTILRKGGRTIAFGGCVF 411
+ G + NA++ CP +HS+A+ + I T+ FGG +
Sbjct 372 SSGMIKPNALLCATCPFAKGDSCSSNCKHSVAQLVSYLSERCNVIADSKSFTLIFGGVAY 431
Query 412 SYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEKVNINIVGDF 467
+Y GC Y+VPRA + + + G G + + + L++ + ++N VG+F
Sbjct 432 AYFGCEEGTMYFVPRAKSVVS-RIGDSIFTGCTGSWNKVTQIANMFLEQTQHSLNFVGEF 490
Query 468 KLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIG--- 524
+N+ + IL+ + + + +KG+ + + + VT G A N+G
Sbjct 491 VVNDVVLAILSGTTTNVDKIRQLLKGVTLDKLRDYLADY-DVAVTAGPFMDNAINVGGTG 549
Query 525 -EQKSILSPLYAFAS--EAARVVRSIFSRTLETAQNSV-----RVLQKAAITILD-GISQ 575
+ +I +P E+ + V +I + + ++++ VL + +D G+S
Sbjct 550 LQYAAITAPYVVLTGLGESFKKVATIPYKVCNSVKDTLTYYAHSVLYRVFPYDMDSGVSS 609
Query 576 YSLRLIDAMMFTSDLATNNLVVMAYITGGVVQ-LTSQWLTNIFGTVYEKLKPVLDWLEEK 634
+S L D + + V Y ++Q T +++ I + + +LD E
Sbjct 610 FSELLFDCVDLS--------VASTYFLVRLLQDKTGDFMSTIITSCQTAVSKLLDTCFEA 661
Query 635 FKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII 694
+ FL D + + A V ++ V+ L+NK + L +
Sbjct 662 TEATFNFLLDLAGLFRIFLRNAYVYTSQGFVVVNGKVSTLVKQVLDLLNKGMQLLHTKVS 721
Query 695 IGGAKLKA-LNLGETFVTHSKGLYRKCVKSR-----EETGLLMPLKAPKEIIFLEGETLP 748
G+ + A + G + G Y CV ++ ++ +++P + K+ + L T
Sbjct 722 WAGSNISAVIYSGRESLIFPSGTYY-CVTTKAKSVQQDLDVILPGEFSKKQLGLLQPTDN 780
Query 749 TEVLTEEVV--LKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEI--KDTEKYCALAP 804
+ ++ V + + LEQ + + +VG V I+ + + +D +
Sbjct 781 STTVSVTVSSNMVETVVGQLEQTNMHSPDV-IVGDYVIISEKLFVRSKEEDGFAFYPACT 839
Query 805 NMMVTNNTFTLKGGAP-TKVTFGDDTVIEVQGYKSVNITFELDERIDKVL-NEKCSAYTV 862
N F LKGGAP KV FG D V EV +SV + + + +D +L + + V
Sbjct 840 NGHAVPTLFRLKGGAPVKKVAFGGDQVHEVAAVRSVTVEYNIHAVLDTLLASSSLRTFVV 899
Query 863 ELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
+ + EFA VV + V L + + DLD++ A Y F+ G+ +S M
Sbjct 900 DKSLSIEEFADVVKEQVSDLLVKLLRGMPIPDFDLDDFIDAPCYCFNAEGDASWSSTMIF 959
Query 923 SFYPPDEDEEEGDCEE---EEFEPSTQYEYGTE----------DDY-----QGKPL-EFG 963
S +P + DEE + E EE E E TE D++ + PL E
Sbjct 960 SLHPVECDEECSEVEASDLEEGESECISETSTEQVDVSHEISDDEWAAAVDEAFPLDEAE 1019
Query 964 ATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQL----------- 1012
+ ++Q E + E ++D +Q + +T + VEV PQ+
Sbjct 1020 DVTESVQEEAQPVEVPVEDIAQVVIADT----LQETPVVSDTVEVPPQVVKLPSEPQTIQ 1075
Query 1013 --------------------EMELTPVVQTIEVNSFS--GYLKLTDNVYIKNADIVEEAK 1050
++ + + V+ S + +T+ V I D ++ AK
Sbjct 1076 PEVKEVAPVYEADTEQTQSVTVKPKRLRKKRNVDPLSNFEHKVITECVTIVLGDAIQVAK 1135
Query 1051 KVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL 1110
+V+VNAAN +LKHGGG+AGA+N A+ A+Q ESD+YI GPL+VG S +L GH+L
Sbjct 1136 CYGESVLVNAANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSL 1195
Query 1111 AKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVR 1170
AK+ LHVVGP+ +D+ LL Y+ N + +++ PL+SAGIFG P S + +
Sbjct 1196 AKNILHVVGPDARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAK 1255
Query 1171 TNVYLAVFDKNLYDKL 1186
T V + V +++Y L
Sbjct 1256 TRVLVVVNSQDVYKSL 1271
>sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus
HKU4 OX=694007 GN=1a PE=1 SV=1
Length=4434
Score = 3715 bits (9634), Expect = 0.0, Method: Composition-based stats.
Identities = 1217/3348 (36%), Positives = 1822/3348 (54%), Gaps = 162/3348 (5%)
Query 1192 EMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIK------ACVEEVTT---- 1241
E + + + + E+ E K I + + ++ R+ K+ + T
Sbjct 1111 ENQVHQVSDLQGNELLCSETKVEIVQPRQDLKPRRSRKSKVDLSKYKHTVINNSVTLVLG 1170
Query 1242 -TLEETKFLTENLLLYI---------DINGNLHPDSATLVSDIDITFLKKDAPYIVGD-V 1290
++ L + +L+ I G ++ S V + ++ + P VGD V
Sbjct 1171 DAIQIASLLPKCILVNAANRHLKHGGGIAGVINKASGGDVQEESDEYISNNGPLHVGDSV 1230
Query 1291 VQEGVLTA-----VVIPTKKAGGTTEMLAKALRKV-PTDNYITTYPGQGLNG-------- 1336
+ +G A VV P + +L + + +T G+
Sbjct 1231 LLKGHGLADAILHVVGPDARNNEDAALLKRCYKAFNKHTIVVTPLISAGIFSVDPKVSFE 1290
Query 1337 YTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLAHAEETRKLMPVCVETK 1396
Y + T + I ++ + K + L R + A+ +C E
Sbjct 1291 YLLANVTTTTYVVVNNEDIYNTLATPSKPDGLVYSFEGWRGTVRTAKNYGFTCFICTEYS 1350
Query 1397 AIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHG 1456
A V ++ K + VD G +Y Y+++ + +I N + + MP GYVTHG
Sbjct 1351 ANVKFLRTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGCS-GICAMPFGYVTHG 1408
Query 1457 LNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGSYKDWSY 1516
L+L ++ Y+R +KVP ++S + + N + + +TPE FI ++ G Y W
Sbjct 1409 LDLAQSGNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGGYHSWHL 1466
Query 1517 -SGQSTQLGI---EFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLLSLREVR-----T 1567
SG + + L +++ Y N + + F +L+ + R
Sbjct 1467 VSGDLIVKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFSDLEACRAYLTSRAAQQVN 1526
Query 1568 IKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD-T 1626
I+V T+D +N T +++ + T+ +Q G T+ G D++ P G++ +V N +
Sbjct 1527 IEVLVTIDGVNFRTVILNDTTTFRKQLGATFYKGVDISDAFPTVKMGGESLFVADNLSES 1586
Query 1627 LRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQI 1686
+V EYY T+D +FL RY S ++WK+ +G+ S+K ++ NCY+ ++ + +
Sbjct 1587 EKVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATIMMIDML 1646
Query 1687 -ELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLD-SC 1744
++KF PALQ+AY R + G+ +F ALI+AY + T D + + L A L S
Sbjct 1647 HDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKAELTVSA 1706
Query 1745 KRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
K V C CG + G+ A +Y G S E+ + C CG + LV+ +P+
Sbjct 1707 KMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLVEHSAPW 1766
Query 1805 VMMSAPPAQYELKHG--TFTCASEYTG-NYQCGHYKHITSKETL-YCIDGALLTKSSEYK 1860
+++S + + + G GHY HI K+ L Y D LTK+S+ K
Sbjct 1767 LLVSGLNEVKVSTSTDPIYRAFNVFQGVETSVGHYVHIRVKDGLFYKYDSGSLTKTSDMK 1826
Query 1861 GPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQP-IDLVPNQP 1919
+T V+Y YT V Y LDGV E++P L NYY KD Y+T +P I P
Sbjct 1827 CKMTSVWYPTVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKPTIKYSPATI 1886
Query 1920 YPNASFDNFKFVCDNIKFADD-----LNQLTGYK--KPASRELKVTFFPDLNGDVVAIDY 1972
P + + N V + D N L G+ KP S++L + P+ +GDV+ ++
Sbjct 1887 LPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNEDGDVLLSEF 1946
Query 1973 KHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSED 2032
+Y P +KKG L KPI+W N + A KPN +R L+ P+ N + VL+
Sbjct 1947 SNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDNKYTVLQDNT 2006
Query 2033 AQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTE---VVGDIILKPANNSLKITEE 2089
+Q + E PV ++V P + ++E K V G+ N + + +
Sbjct 2007 SQLV-----EHNVPVVDDV---PITTRKLIEVKCKGLNKPFVKGNFSFVNDPNGVTVVDT 2058
Query 2090 VGHTDLMAAYVD-NSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDT----IANYAKP 2144
+G T+L A YVD N+ + + N S + L T+ + L V + T + A
Sbjct 2059 LGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVESGDLQIVAAGGSVTRRARVLLGASS 2118
Query 2145 FLNKVVSTTTNIVTRCLNRVCTNY----------------MPYFFTLLLQLCTFTRSTNS 2188
T T + + F L +
Sbjct 2119 LFASFAKITVTATTAACKTAGRGFCKFVVNYGVLQNMFVFLKMLFFLPFNYLWPKKQPTV 2178
Query 2189 RIKAS---MPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINI-------------IIW 2232
I S + N VK G K ++ + + I
Sbjct 2179 DIGVSGLRTAGIVTTNIVKQCGTAAYYMLLGKFKRVDWKATLRLFLLLCTTILLLSSIYH 2238
Query 2233 FLLLSVCLGSLIYSTAALGVLM------SNLGMPSYCTGYREGYLNSTNVTIATYCTG-S 2285
+L + L S + A G+L S LG+ + C G Y N T+ + +C+ S
Sbjct 2239 LVLFNQVLSSDVMLEDATGILAIYKEVRSYLGIRTLCDGLVVEYRN-TSFDVMEFCSNRS 2297
Query 2286 IPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAA 2345
+ C CL G DSL Y +L+ +Q I+S+ ++ E+FLAY+L+T F VL L
Sbjct 2298 VLCQWCLIGQDSLTRYSALQMLQTHITSYVLNIDWIWFALEFFLAYVLYTSSFNVLLLVV 2357
Query 2346 IMQLFFSYFA--VHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDG 2403
Q FF+Y + V++ + ++++ + LV P+ +VR+Y F A +++ K Y HV++G
Sbjct 2358 TAQYFFAYTSAFVNWRAYNYIVSGLFFLVTHIPLHGLVRVYNFLACLWFLRKFYSHVING 2417
Query 2404 CNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGST 2463
C + C++CYKRNR TRVE +TIV G +R+FY+ ANGG +C HNWNCV CDT G+T
Sbjct 2418 CKDTACLLCYKRNRLTRVEASTIVCGTKRTFYIAANGGTSYCCKHNWNCVECDTAGVGNT 2477
Query 2464 FISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVN 2523
FI EVA DL+ +R I PTDQS Y VDSV VK+ + L++++ G YER+ L +F N
Sbjct 2478 FICTEVANDLTTTLRRLIKPTDQSHYYVDSVVVKDAVVELHYNRDGSSCYERYPLCYFTN 2537
Query 2524 LDNLRANN----TKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSD 2579
L+ L+ G N +++D + +E+ A+SA VYYSQ++C+P+LL+D LV+
Sbjct 2538 LEKLKFKEVCKTPTGIPEHNFLIYDTNDRGQENLARSACVYYSQVLCKPMLLVDVNLVTT 2597
Query 2580 VGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAAR- 2638
VGDS E+A+KM D+++N+F S F+V +KL+ L+ TA + + NVL TF AAR
Sbjct 2598 VGDSREIAIKMLDSFINSFISLFSVSRDKLEKLINTARDCVRRGDDFQNVLKTFTDAARG 2657
Query 2639 QGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARH 2698
V+SDVET VV+ L+ +H++DI++T + NNY+ Y K +++ DLG ID A
Sbjct 2658 HAGVESDVETTMVVDALQYAHKNDIQLTTECYNNYVPGYIKPDSINTLDLGCLIDLKAAS 2717
Query 2699 INAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKI 2758
+N ++ N A +WN D+M LS+ ++QIR A +K N+PF+LT + R N+++ K
Sbjct 2718 VNQTSMRNANGACVWNSGDYMKLSDSFKRQIRIACRKCNIPFRLTTSKLRAADNILSVKF 2777
Query 2759 AL-KGGKIVNNWL--------KQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGY 2809
+ K +WL K +TL VA + + P + ++ I+ Y
Sbjct 2778 SATKIVGGAPSWLLRVRDLTVKGYCILTLFVFTVAVLSWFCLPSYSIATVNFNDDRILTY 2837
Query 2810 KAIDGGVTRDIASTDTCFANKHADFDTWFSQ-RGGSYTNDKACPLIAAVITREVGFVVPG 2868
K I+ G+ RDIA D CFANK+ F WF++ GG Y N CP+ AVI G V
Sbjct 2838 KVIENGIVRDIAPNDVCFANKYGHFSKWFNENHGGVYRNSMDCPITIAVIAGVAGARVAN 2897
Query 2869 LPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGK 2928
+P + + F+ RVF A N+C+TP I Y F+ S CVL++ECT+F+DA G
Sbjct 2898 VPANLAWV-GKQIVLFVSRVF-ANTNVCFTPINEIPYDTFSDSGCVLSSECTLFRDAEGN 2955
Query 2929 PVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHG 2987
P+CYD VL G+ +Y ++P RY + D I+FP +E ++R+ T ++YCR G
Sbjct 2956 LNPFCYDPTVLPGASSYADMKPHVRYDMYDSDMYIKFPEVIVESTLRITKTLATQYCRFG 3015
Query 2988 TCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASI 3047
+CE S AGVC+ST+G W L N Y + PG++CG D +++ + L QP+ +S S+
Sbjct 3016 SCEESAAGVCISTNGSWALYNQNYSTRPGIYCGDDYFDIVRRLAISLFQPVTYFQLSTSL 3075
Query 3048 VAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSV 3107
G ++ + +T YY + +RA +Y+ + L++ LC L Y+
Sbjct 3076 AMGLVLCVFLTAAFYYINKVKRALADYTQCAVVAVVAALLNSLCLCFIVANPLLVAPYTA 3135
Query 3108 IYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV-- 3165
+Y Y TFYLT + +F+ HI W VMF +VP W+ +Y + + +H +W + + K+ V
Sbjct 3136 MYYYATFYLTGEPAFIMHISWYVMFGAVVPIWMLASYTVGVMLRHLFWVLAYFSKKHVDV 3195
Query 3166 VFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTS 3225
+G +F++AA F++ K+ Y+ LR+ + + RYL+L+NKYKY+SGAMDT S
Sbjct 3196 FTDGKLNCSFQDAASNIFVIGKDTYVALRNAI--TQDSFVRYLSLFNKYKYYSGAMDTAS 3253
Query 3226 YREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTC 3285
YREA HL KAL +S +GSD+LYQPP S+TS+VLQSG KM+ PSG VE C+VQVTC
Sbjct 3254 YREACAAHLCKALQTYSETGSDILYQPPNCSVTSSVLQSGLVKMSAPSGAVENCIVQVTC 3313
Query 3286 GTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQ---AGNVQLRVIG 3342
G+ TLNGLWLD+ V+CPRH++C ++ + +PNY+ LLI K+NH+F+VQ LRV+
Sbjct 3314 GSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLISKTNHSFIVQKHIGAQANLRVVA 3373
Query 3343 HSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGS 3402
HSM +LKL VD ANP TP Y F ++PG +FSVLACYNG P+GV+ +R N TIKGS
Sbjct 3374 HSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKGS 3433
Query 3403 FLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTT 3462
FL GSCGSVG+ + ++F YMH MEL G H G+ +G YG F D+QT Q TD
Sbjct 3434 FLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDKY 3493
Query 3463 ITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGI 3522
T+NV+AWLYAAV+NG +WF+ + +N A+ + + L+ +TG+
Sbjct 3494 CTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVG--TQSIDMLAHRTGV 3551
Query 3523 AVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHW 3582
+V M A+++ L G G+TILG + LEDEFTP DV Q GV QS VKR G HW
Sbjct 3552 SVEQMLAAIQSL-HAGFQGKTILGQSTLEDEFTPDDVNMQVMGVVMQSGVKRISYGFIHW 3610
Query 3583 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLP 3642
L+ T + + + ++Q T+++++ +L+E ++ A M VKHKH F+ LFLLP
Sbjct 3611 LISTFVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLLGFMACVMFTVKHKHTFMSLFLLP 3670
Query 3643 SLATVAYFNMVYMP----ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTAR 3698
+ Y N+VY P +S ++ + WL + D +Y S +L ++ R
Sbjct 3671 VALCLTYANIVYEPQTLISSTLIAVANWLTPTSVYMRTTHF-DFGLYISLSFVLAIIVRR 3729
Query 3699 TVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGI 3758
+ L + + Y G+ I+ I ++TS+Y+ V + LA+ I
Sbjct 3730 LYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYTITVFATVNLAKFI 3788
Query 3759 VFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQ 3818
+ Y P ++ ++L+Y LGY CT YFG+F LLN R+ LGVYDY VSTQ
Sbjct 3789 SGLVFFYAPHLGFILPEVKLVLLIYLGLGYMCTMYFGVFSLLNLKLRVPLGVYDYSVSTQ 3848
Query 3819 EFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQ 3878
EFR++ GL P+NS +A LN KLLG+GG PCIKVATVQSK++D+KCTSVVLL+VLQQ
Sbjct 3849 EFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQSKLTDLKCTSVVLLTVLQQ 3908
Query 3879 LRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNR 3938
L +ES+SK W+ CV+LHN+IL A D TEAFE+ V L + L+S VD++ L ++ +N
Sbjct 3909 LHLESNSKAWSYCVKLHNEILAAVDPTEAFERFVCLFATLMSFSANVDLDALANDLFENS 3968
Query 3939 ATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAM 3997
+ LQA +EFS L +YA TAQ +Y++A+ +GD S VLK L+K++NVAK+ +++D A+
Sbjct 3969 SVLQATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAV 4028
Query 3998 QRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCV 4057
RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GCV
Sbjct 4029 ARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCV 4088
Query 4058 PLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD 4117
PL+I+PL + KL VVIPD + + + + +YA +LW+I + + D+++V+ +++ ++
Sbjct 4089 PLSIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVVKPTDV-VE 4147
Query 4118 NSPNLAWPLIVTALR-ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTK 4176
+ +L WPL++ R ++SAVKLQNNE+ P L+ M AG Q C + +A+AYY +
Sbjct 4148 TNESLTWPLVIECSRSSSSAVKLQNNEIHPKGLKTMVITAGVDQVNC-NSSAVAYYEPVQ 4206
Query 4177 GGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNN 4236
G R V+ LLS+ LKWA+ DG I EL+PPC+F+ PKGP+++YLYF+K LNN
Sbjct 4207 GHRMVMGLLSENAHLKWAKVEGKDGF--INIELQPPCKFLIAGPKGPEIRYLYFVKNLNN 4264
Query 4237 LNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVK 4296
L+RG +LG +AATVRLQAG TE +NSTVL+ AFAVD AKAY DY+ SGG P++N VK
Sbjct 4265 LHRGQLLGHIAATVRLQAGANTEFASNSTVLTLVAFAVDPAKAYLDYVGSGGTPLSNYVK 4324
Query 4297 MLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTC 4356
ML TGTG AI+V PEA DQE++GGAS CLYCR HI+HP+ G C K ++VQIP
Sbjct 4325 MLAPKTGTGVAISVKPEATADQETYGGASVCLYCRAHIEHPDVSGVCKYKTRFVQIPA-H 4383
Query 4357 ANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVC 4404
DPVGF LKN C VC W GYGC+CD LR + + +FLN
Sbjct 4384 VRDPVGFLLKNVPCNVCQYWVGYGCNCDALRNNTVPQSKDTNFLNESG 4431
Score = 939 bits (2427), Expect = 0.0, Method: Composition-based stats.
Identities = 307/1330 (23%), Positives = 529/1330 (40%), Gaps = 184/1330 (14%)
Query 8 FNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEVLSEARQHLKD-GTCGLVEVE-KGV 60
+NEK HV ++P+ D+ L F D E ++ LK+ G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTDDMACKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGR-----SGETLGVLVPHVGEIP 115
+ L P V++ H +V +A + + + + LG+ P+ +
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDQVGAAMMRTTLNAKPLGMFFPYDSSLE 139
Query 116 VAYRKVLLRKNGNKGAGGHSYGADLKS---FDLGDELGTDPYEDFQENWNTKHSSGVTRE 172
LLRKNG G D K ++ D+L DP + +N
Sbjct 140 TGEYTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCT--LSEQLDFIDTKRGVYC 230
L+++L GG +D CG +G P+ ++A+ G + + +D+ R +
Sbjct 188 LLKKLIGGDCIP-IDQYMCGKNGKPIADYAKIVAKEGLTTLADIEVDVKSRMDSDRFI-V 245
Query 231 CREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEK 290
+ + + W R Y QT F I + D P F + S I + P ++
Sbjct 246 LNKKLYRVVWNVTRRNVPYPKQTAFTIVSVVQCDD-KDSVPEHTFTIGSQILMVSP-LKA 303
Query 291 KKLDGFMGRIRSVYPVAS---PNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTE 347
F + R +Y + + S + C+ CG +W TG+ ++ CG
Sbjct 304 TNNKNFNLKQRLLYTFYGKDAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGAN 363
Query 348 NLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGR--TI 404
+ + G +P+NA+ CP +N HS A+ +N K + GG+ T+
Sbjct 364 YSANDVDLQSSGLVPRNALFLANCPCANNGAC--SHSAAQVYNILDGKACVEVGGKSFTL 421
Query 405 AFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEKVN 460
FGG V++Y+GC + Y+VPRA + + + G G D ++E L+K + +
Sbjct 422 TFGGVVYAYMGCCDGTMYFVPRAKSCVS-RIGDAIFTGCTGTWDKVVETANLFLEKAQRS 480
Query 461 INIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN--FKVTKGKAKK 518
+N F L E ++LA S +TS F E +++++ + N F VT G +
Sbjct 481 LNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDYIR 537
Query 519 GAWNIGEQ----KSILSPLYAFAS--EAARVVRSIFSRTLETAQNSVRVLQKAAITILDG 572
A NIG +I +P AF E+ + V +I + N L + I+
Sbjct 538 DAINIGANGVCNATINAPFIAFTGLGESFKKVSAI---PWKICSNLKSALDYYSSNIMFR 594
Query 573 ISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGT----VYEKLKPVL 628
+ Y + D F L + +A + V++ + + GT L L
Sbjct 595 VFPYDIP-CDVSNFVELLLDCGKLTVA-TSYFVLRYLDEKFDTVLGTVSSACQTALSSFL 652
Query 629 DWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLAL 688
+ + F+ D +++ K + V A+ + VQ +++K + L
Sbjct 653 NACVAASRATAGFINDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLDIMSKAMKL 712
Query 689 CADSIIIGGAKLKALNL-GETFVTHSKGLYRKCVKSRE-----ETGLLMPLKAPKEIIFL 742
++ G KL A+ G + + G Y C+ ++ + L++P K+ + +
Sbjct 713 LHTNVSWAGTKLSAIIYEGREALLFNSGTYF-CLSTKAKTLQGQMNLVLPGDYNKKTLGI 771
Query 743 -----EGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTE 797
+T+ + V + G L+P T+E + +VG V ++ + + +D E
Sbjct 772 LDPVPNADTIDVNANSTVVDVVHGQLEP----TNEHGPSMIVGNYVLVSDKLFVRTEDEE 827
Query 798 KYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSVNITFELDERIDKVLNE- 855
Y L N V + F LKGG P+K VTFGD +EV Y+SV+IT+++ +D +L+
Sbjct 828 FYP-LCTNGKVVSTLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPVLDALLSSS 886
Query 856 KCSAYTVEL-----------------------------GTEVNEFACVVADAVIKTLQPV 886
K + +TVE G +V +F V V
Sbjct 887 KLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPC-YVYNQDGDC 945
Query 887 S-------ELLTPLGIDLDEWSMATYYLFDE----SGEFKLA------------------ 917
+ + ++ E + YL DE E A
Sbjct 946 AWSSNMTFSINPVEDVEEVEEFIEDDYLSDELPIADDEEAWARAVEEVMPLDDILVAEIE 1005
Query 918 ----SHMYCSFYPPDEDEEEGDCEEEEFEPSTQYE------YGTEDDYQGKPLEFGATSA 967
+ + + + E +E S G D T
Sbjct 1006 LEEDPPLETALESVEAEVVETAEAQEPSVESIDSTPSTSTVVGENDLSVKPMSRVAETDD 1065
Query 968 ALQPEEEQEEDWLDDDSQQTVGQ-----------------QDGSEDNQT----------- 999
L+ E + D + QD + +NQ
Sbjct 1066 VLELETAVVGGPVSDVTAIVTNDIVSVEQAQQCGVSSLPIQDEASENQVHQVSDLQGNEL 1125
Query 1000 -TTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVV 1058
+ + VQP+ +++ ++ S + + ++V + D ++ A + ++V
Sbjct 1126 LCSETKVEIVQPRQDLKPRRSRKSKVDLSKYKHTVINNSVTLVLGDAIQIASLLPKCILV 1185
Query 1059 NAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVV 1118
NAAN +LKHGGG+AG +NKA+ +Q ESD+YI+ NGPL VG S +L GH LA LHVV
Sbjct 1186 NAANRHLKHGGGIAGVINKASGGDVQEESDEYISNNGPLHVGDSVLLKGHGLADAILHVV 1245
Query 1119 GPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVF 1178
GP+ ED LLK Y+ FN+H +++ PL+SAGIF DP S + V T Y+ V
Sbjct 1246 GPDARNNEDAALLKRCYKAFNKHTIVVTPLISAGIFSVDPKVSFEYLLANVTTTTYVVVN 1305
Query 1179 DKNLYDKLVS 1188
++++Y+ L +
Sbjct 1306 NEDIYNTLAT 1315
>sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus
133/2005 OX=389230 GN=1a PE=3 SV=1
Length=4441
Score = 3714 bits (9630), Expect = 0.0, Method: Composition-based stats.
Identities = 1204/3259 (37%), Positives = 1792/3259 (55%), Gaps = 138/3259 (4%)
Query 1259 INGNLHPDSATLVSDIDITFLKKDAPYIVGD-VVQEGVLTA-----VVIPTKKAGGTTEM 1312
I G ++ S V + ++ P VGD V+ +G A VV P + +
Sbjct 1205 IAGAINKASGGDVQEESDEYISNSGPLHVGDSVLLKGYGLADAILRVVGPDARNNEDAAL 1264
Query 1313 LAKALRKV-PTDNYITTYPGQGLNG--------YTVEEAKTVLKKCKSAFYILPSIISNE 1363
L + + +T G+ Y + T + I ++ +
Sbjct 1265 LKRCYKTFNKHTIVVTPLISSGIFSVDPKVSFEYLLANVTTTTYVVVNNEDIYNTLATPS 1324
Query 1364 KQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFY 1423
K + L R + A+ +C E A V ++ K + VD G +Y
Sbjct 1325 KPDGLVYSFEGWRGTVRTAKNYGFTCFICTEYSANVKFLRTKGVDTTKKIQTVD-GVSYY 1383
Query 1424 FYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAV 1483
Y+++ + +I N + MP GYVTHGL+L ++ Y+R +KVP ++S + +
Sbjct 1384 LYSARDALTDVIAAANGC-PGICAMPFGYVTHGLDLAQSGNYVRQVKVPYVCLLASKEQI 1442
Query 1484 TAYNGYLTSSSKTPEEHFIETISLAGSYKDWSY-SGQSTQLGI---EFLKRGDKSVYYTS 1539
N + + +TPE FI ++ G Y W SG + + L +++ Y
Sbjct 1443 PIMNSDV--AIQTPETAFINNVTSNGGYHSWHLVSGDLIVKDVCYKKLLHWSGQTICYAD 1500
Query 1540 NPTTFHLDGEVITFDNLKTLLSLREVR-----TIKVFTTVDNINLHTQVVDMSMTYGQQF 1594
N + + F +L+ + R I+V T+D +N T +++ + T+ +Q
Sbjct 1501 NKFYVVKNDVALPFSDLEACRAYLTSRAAQQVNIEVLVTIDGVNFRTVILNDATTFRKQL 1560
Query 1595 GPTYLDGADVTKIKPHNSHEGKTFYVLPNDD-TLRVEAFEYYHTTDPSFLGRYMSALNHT 1653
G T+ G D++ P G++ +V N + V EYY T+D +FL RY S
Sbjct 1561 GATFYKGVDISDALPTVKMGGESLFVADNLSESEEVVLKEYYGTSDVTFLQRYYSLQPLV 1620
Query 1654 KKWKYPQVNGLTSIKWADNNCYLATALLTLQQI-ELKFNPPALQDAYYRARAGEAANFCA 1712
++WK+ +G+ S+K ++ NCY+ ++ + + ++KF PALQ+AY R + G+ +F A
Sbjct 1621 QQWKFVVHDGVKSLKLSNYNCYINATIMMIDMLHDIKFVVPALQNAYLRYKGGDPYDFLA 1680
Query 1713 LILAYCNKTVGELGDVRETMSYLFQHANLD-SCKRVLNVVCKTCGQQQTTLKGVEAVMYM 1771
LI+AY + T D + + L A L S K V C CG + G+ A +Y
Sbjct 1681 LIMAYGDCTFDNPDDEAKLLHTLLAKAELTVSAKMVWREWCTVCGIRDIEYTGMRACVYA 1740
Query 1772 GTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHG--TFTCASEYTG 1829
G S E+ + C CG + LV+ +P++++S + + + G
Sbjct 1741 GVNSMEELQSVFNETCVCGSVKHRQLVEHSTPWLLVSGLNEVKVSTSTDPVYRAFNVFQG 1800
Query 1830 -NYQCGHYKHITSKETL-YCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGV 1887
GHY H+ K+ L Y D LTK+S+ K +T V+Y + YT V Y LDGV
Sbjct 1801 VETSVGHYVHVRVKDGLFYKYDSGSLTKTSDMKCKMTSVWYPKVRYTADCNVVVYDLDGV 1860
Query 1888 VCTEIDPKLDNYYKKDNSYFTEQP-IDLVPNQPYPNASFDNFKFVCDNIKFADD-----L 1941
E++P L NYY KD Y+T +P I P P + + N V + D
Sbjct 1861 TKVEVNPDLSNYYMKDGKYYTSKPTIKYSPATILPGSVYSNSCLVGVDGTPGSDTISKFF 1920
Query 1942 NQLTGYK--KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATN 1999
N L G+ KP S++L + P+ +GDV+ ++ +Y P +KKG L KPI+W N +
Sbjct 1921 NDLLGFDETKPISKKLTYSLLPNEDGDVLLSEFNNYNPVYKKGVMLKGKPILWVNNGVCD 1980
Query 2000 KATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQK 2059
A KPN +R L+ P+ N + VL+ +Q + E PV E+V T +
Sbjct 1981 SALNKPNRASLRQLYDVAPIVLDNKYTVLQDNTSQLI-----EPNVPVVEDVS-ITTRKL 2034
Query 2060 DVLECNVKTTEVV-GDIILKPANNSLKITEEVGHTDLMAAYVD-NSSLTIKKPNELSRVL 2117
++C V G+ N + + + +G T+L A YVD N+ + + N S +
Sbjct 2035 IEVKCKGLNKPFVKGNFSFVNDPNGVTVVDTLGLTELRALYVDINTRYIVLRDNNWSSLF 2094
Query 2118 GLKTLATHGLAAVNSVPWDT----IANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFF 2173
L T+ + L V + T + A T T ++ +
Sbjct 2095 KLHTVESGDLQIVANGGSVTRRARVLLGASSLFASFAKITVTATTAACKTAGRSFCKFVV 2154
Query 2174 TL----------------LLQLCTFTRSTNSRIKAS---MPTTIAKNTVKSVGKFCLEAS 2214
+ + S + N VK G
Sbjct 2155 NYGVLQNMFLFLKMLFFLPFNYLWPKKQPTVDVGVSGLRTAGVVTTNIVKQCGTAAYYML 2214
Query 2215 FNYLKSPNFSKLINI-------------IIWFLLLSVCLGSLIYSTAALGVLM------S 2255
K ++ + + I ++ + L S + A G+L S
Sbjct 2215 LGKFKRVDWKATLRLFLLLCTTILLLSSIYHLVIFNQVLSSDVMLEDATGILAMYKEVRS 2274
Query 2256 NLGMPSYCTGYREGYLNSTNVTIATYCTG-SIPCSVCLSGLDSLDTYPSLETIQITISSF 2314
LG+ + C G Y N T+ + +C+ S+ C CL G DSL Y +L+ +Q I+S+
Sbjct 2275 YLGIRTLCDGLAVEYRN-TSFDVVDFCSNRSVLCQWCLIGQDSLTRYSALQMLQTHITSY 2333
Query 2315 KWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFA--VHFISNSWLMWLIINLV 2372
++ E+FLAY+L+T F VL L Q FF+Y + V++ + ++++ + LV
Sbjct 2334 VLNIDWIWFALEFFLAYVLYTSSFNVLLLVVTAQYFFAYTSAFVNWRAYNYIVSGLFFLV 2393
Query 2373 QMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRR 2432
P+ +VR+Y F A +++ K Y HV++GC + C++CYKRNR TRVE +TIV G +R
Sbjct 2394 THIPLHGLVRVYNFLACLWFLRKFYSHVINGCKDTACLLCYKRNRLTRVEASTIVCGTKR 2453
Query 2433 SFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVD 2492
+FY+ ANGG +C HNWNCV CDT G+TFI EVA DL+ +R I PTDQS Y VD
Sbjct 2454 TFYIAANGGTSYCCKHNWNCVECDTAGVGNTFICTEVANDLTTTLRRLIKPTDQSHYYVD 2513
Query 2493 SVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANN----TKGSLPINVIVFDGKSK 2548
SV VK+ + L++++ G YER+ L +F NL+ L+ G N +++D +
Sbjct 2514 SVVVKDAVVELHYNRDGSSCYERYPLCYFTNLEKLKFKEVCKTPTGIPEHNFLIYDTNDR 2573
Query 2549 CEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEK 2608
+E+ A+SA VYYSQ++C+P+LL+D LV+ VGDS E+A+KM D+++N+F S F+V +K
Sbjct 2574 GQENLARSACVYYSQVLCKPMLLVDVNLVTTVGDSREIAIKMLDSFINSFISLFSVSRDK 2633
Query 2609 LKTLVATAEAELAKNVSLDNVLSTFISAAR-QGFVDSDVETKDVVECLKLSHQSDIEVTG 2667
L+ L+ TA + + VL TF AAR V+SDVET VV+ L+ +H++DI++T
Sbjct 2634 LEKLINTARDCVRRGDDFQTVLKTFTDAARGHAGVESDVETTMVVDALQYAHKNDIQLTT 2693
Query 2668 DSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRK 2727
+ NNY+ Y K +++ DLG ID A +N ++ N A +WN D+M LS+ ++
Sbjct 2694 ECYNNYVPGYIKPDSINTLDLGCLIDLKAASVNQTSMRNANGACVWNSGDYMKLSDSFKR 2753
Query 2728 QIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL-KGGKIVNNWL--------KQLIKVTL 2778
QIR A +K N+PF+LT + R N+++ K + K +WL K +TL
Sbjct 2754 QIRIACRKCNIPFRLTTSKLRAADNILSVKFSATKIVGGAPSWLLRVRDLTVKGYCILTL 2813
Query 2779 VFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWF 2838
VA + + P + ++ I+ YK I+ G+ RDIA D CFANK+ F WF
Sbjct 2814 FVFTVAVLSWFCLPSYSIATVNFNDDRILTYKVIENGIVRDIAPNDACFANKYGHFSKWF 2873
Query 2839 SQ-RGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICY 2897
++ GG Y N CP+ AVI G V +P T+ + F+ RVF A N+C+
Sbjct 2874 NENHGGVYRNSVDCPITIAVIAGVAGARVANVPATLAWV-GRQIVLFVSRVF-ANTNVCF 2931
Query 2898 TPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLM 2957
TP+ I Y F+ S CVL++ECT+F+DA G P+CYD VL G+ +Y ++P RY +
Sbjct 2932 TPTNEIPYDTFSDSGCVLSSECTLFRDAEGNLNPFCYDPTVLPGASSYADMKPHVRYDMY 2991
Query 2958 DGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPG 3016
D I+FP E ++R+ T ++YCR G+CE S AGVC+ST+G W L N Y + PG
Sbjct 2992 DSDMYIKFPEVIFESTLRITKTLATQYCRFGSCEESAAGVCISTNGSWALYNQNYSTRPG 3051
Query 3017 VFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSH 3076
++CG D +++ + L QP+ +S S+ G ++ + +T YY + +RA +Y+
Sbjct 3052 IYCGDDYFDIVRRLAVSLFQPVTYFQLSTSLAMGLVLCVFLTAAFYYINKVKRALADYTQ 3111
Query 3077 VVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLV 3136
+ L++ LC L Y+ +Y Y TFYLT + +F+ HI W VMF +V
Sbjct 3112 CAVVAVVAALLNSLCLCFIVANPLLVAPYTAMYYYATFYLTGEPAFIMHISWYVMFGTVV 3171
Query 3137 PFWITIAYIICISTKHFYWFFSNYLKRRV--VFNGVSFSTFEEAALCTFLLNKEMYLKLR 3194
P W+ +Y + + +H +W + + K+ V +G +F++AA F++ K+ Y+ LR
Sbjct 3172 PIWMLASYTVGVMLRHLFWVLAYFSKKHVDVFTDGKLNCSFQDAASNIFVIGKDTYVALR 3231
Query 3195 SDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQ 3254
+ + + RYL+L+NKYKY+SGAMDT SYREA HL KAL +S +GSD+LYQPP
Sbjct 3232 NAI--TQDSFVRYLSLFNKYKYYSGAMDTASYREACAAHLCKALQTYSETGSDILYQPPN 3289
Query 3255 TSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLN 3314
S+TS+VLQSG KM+ PSG VE C+VQVTCG+ TLNGLWLD+ V+CPRH++C ++ + +
Sbjct 3290 CSVTSSVLQSGLVKMSAPSGAVENCIVQVTCGSMTLNGLWLDNTVWCPRHIMCPADQLTD 3349
Query 3315 PNYEDLLIRKSNHNFLVQ---AGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQP 3371
PNY+ LLI K+NH+F+VQ LRV+ HSM +LKL VD ANP TP Y F ++P
Sbjct 3350 PNYDALLISKTNHSFIVQKHIGAQANLRVVAHSMVGVLLKLTVDVANPSTPAYTFSTVKP 3409
Query 3372 GQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELP 3431
G +FSVLACYNG P+GV+ +R N TIKGSFL GSCGSVG+ + ++F YMH MEL
Sbjct 3410 GASFSVLACYNGKPTGVFTVNLRHNSTIKGSFLCGSCGSVGYTENGGVLNFVYMHQMELS 3469
Query 3432 TGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLN 3491
G H G+ +G YG F D+QT Q TD T+NV+AWLYAAV+NG +WF+ +
Sbjct 3470 NGTHTGSSFDGVMYGAFEDKQTHQLQLTDKYCTINVVAWLYAAVLNGCKWFVKPTRVGIV 3529
Query 3492 DFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLE 3551
+N A+ + + L+ +TG++V M A+++ L G G+TILG + LE
Sbjct 3530 TYNEWALSNQFTEFVG--TQSIDMLAHRTGVSVEQMLAAIQSL-HAGFQGKTILGQSTLE 3586
Query 3552 DEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAF 3611
DEFTP DV Q GV QS VKR G HWL+ T++ + + ++Q T+++++ +L+E
Sbjct 3587 DEFTPDDVNMQVMGVVMQSGVKRISYGFMHWLMSTLVLAYVSVMQLTKFTMWTYLFETIP 3646
Query 3612 LPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWL 3667
+ A M VKHKH FL LFLLP + Y N+VY P +S ++ + WL
Sbjct 3647 TQMTPLLFGFMACVMFTVKHKHTFLSLFLLPVALCLTYANIVYEPQTLVSSTLIAVANWL 3706
Query 3668 DMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNAL 3727
+ L D +Y S +L ++ R + L + + Y G+
Sbjct 3707 TPTSVYMRTTHL-DFGLYISLSFVLAIIVRRLYRPSMSNLALALCSGVMWFYTYVIGDH- 3764
Query 3728 DQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLG 3787
I+ I ++TS+Y+ V + LA+ I + Y P ++ ++L+Y LG
Sbjct 3765 SSPITYLMFITTLTSDYTITVFATVNLAKFISGLVFLYAPHLGFILPEVKLVLLIYLCLG 3824
Query 3788 YFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGV 3847
Y CT YFG+F LLN R+ LGVYDY VSTQEFR++ GL P+NS +A LN KLLG+
Sbjct 3825 YMCTMYFGVFSLLNLKLRVPLGVYDYSVSTQEFRFLTGNGLHAPRNSWEALILNFKLLGI 3884
Query 3848 GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEA 3907
GG PCIKVATVQSK++D+KCTSVVLL+VLQQL +ES+SK W+ CV+LHN+IL A D TEA
Sbjct 3885 GGTPCIKVATVQSKLTDLKCTSVVLLTVLQQLHLESNSKAWSYCVKLHNEILAAVDPTEA 3944
Query 3908 FEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQA 3967
FE+ V L + L+S VD++ L ++ +N + LQA +EFS L +YA TAQ +Y++A
Sbjct 3945 FERFVCLFATLMSFSANVDLDALANDLFENSSVLQATLTEFSHLATYAELETAQSSYQKA 4004
Query 3968 VANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVT 4026
+ +GD S VLK L+K++NVAK+ +++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+
Sbjct 4005 LNSGDASPQVLKALQKAVNVAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIV 4064
Query 4027 SAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDG 4086
SAMQTMLF M++KLDND LN +I NAR+GCVPL+I+PL + KL VVIPD + + +
Sbjct 4065 SAMQTMLFGMIKKLDNDVLNGVIANARNGCVPLSIVPLCASNKLRVVIPDISVWNKVVNW 4124
Query 4087 TTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA-NSAVKLQNNELS 4145
+ +YA +LW++ + + D+++V+ +++ ++ + +L WPL++ RA +SAVKLQNNE+
Sbjct 4125 PSVSYAGSLWDVTVINNVDNEVVKPTDV-VETNESLTWPLVIECSRASSSAVKLQNNEIH 4183
Query 4146 PVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTI 4205
P L+ M AG Q C+ +A+AYY +G R V+ LLS+ LKWA+ DG I
Sbjct 4184 PKGLKTMVVTAGIDQVNCS-SSAVAYYEPVQGHRMVMGLLSENAHLKWAKVEGKDGF--I 4240
Query 4206 YTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANST 4265
EL+PPC+F+ PKGP+++YLYF+K LNNL+RG +LG +AATVRLQAG TE +NST
Sbjct 4241 NIELQPPCKFLIAGPKGPEIRYLYFVKNLNNLHRGQLLGHIAATVRLQAGANTEFASNST 4300
Query 4266 VLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGAS 4325
VL+ AFAVD AKAY DY+ SGG P++N VKML TGTG AI+V PEA DQE++GGAS
Sbjct 4301 VLTLVAFAVDPAKAYLDYVGSGGTPLSNYVKMLAPKTGTGVAISVKPEATADQETYGGAS 4360
Query 4326 CCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQ 4385
CLYCR HI+HP+ G C K ++VQIP DPVGF LKN C VC W GYGC+CD
Sbjct 4361 VCLYCRAHIEHPDVSGVCKYKTRFVQIPA-HVRDPVGFLLKNVPCNVCQYWVGYGCNCDA 4419
Query 4386 LREPMLQSADAQSFLNRVC 4404
LR + + +FLN
Sbjct 4420 LRNNTVPQSKDTNFLNESG 4438
Score = 1008 bits (2606), Expect = 0.0, Method: Composition-based stats.
Identities = 313/1336 (23%), Positives = 536/1336 (40%), Gaps = 189/1336 (14%)
Query 8 FNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEVLSEARQHLKD-GTCGLVEVE-KGV 60
+NEK HV ++P+ D+ L F D E ++ LK+ G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTEDMASKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETL-----GVLVPHVGEIP 115
+ L P V++ H +V +A + + TL G+ P+ +
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDHVGAAMMRTTLNVKPLGMFFPYDSSLE 139
Query 116 VAYRKVLLRKNGNKGAGGHSYGADLKS---FDLGDELGTDPYEDFQENWNTKHSSGVTRE 172
LLRKNG G D K ++ D+L DP + +N
Sbjct 140 TGEHTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCT--LSEQLDFIDTKRGVYC 230
L+++L GG VD CG +G P+ ++A+ G + + +D+ R +
Sbjct 188 LLKKLIGGDCIP-VDQYMCGKNGKPIADYAKIVAKEGLTTLADIEVDVKSRMDSDRFI-V 245
Query 231 CREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEK 290
+ + + W R Y QT F + + D P F + S I + P ++
Sbjct 246 LNKKLYRVVWNVTRRNVPYSKQTAFTVVSVIQCDD-KESVPEHTFTIGSQILMVSP-LKA 303
Query 291 KKLDGFMGRIR---SVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTE 347
F + R + Y + + + S + C+ CG +W TG+ ++ CG
Sbjct 304 TNNKNFNLKQRLLHTFYGKEAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGAN 363
Query 348 NLTKE-GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGR--TI 404
+ + G +P+NA+ CP +N H+ A+ ++ K + GG+ T+
Sbjct 364 YSANDVDLQSSGLVPKNALFLANCPCANNGAC--SHNAAQVYSILDGKACVEVGGKSFTL 421
Query 405 AFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLE----ILQKEKVN 460
FGG V++Y+GC + Y+VPRA + + + G G D ++E L+K + +
Sbjct 422 TFGGVVYAYMGCCDGTMYFVPRAKSCVS-RIGDAIFTGCTGTWDKVVETANLFLEKAQHS 480
Query 461 INIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN--FKVTKGKAKK 518
+N F L E ++LA S +TS F E +++++ + N F VT G +
Sbjct 481 LNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDYIR 537
Query 519 GAWNIGE----QKSILSPLYAFA--SEAARVVRSIFSRTLETAQNSVRVLQKAAITILDG 572
A NIG +I +P AF E+ + V +I + N L I+
Sbjct 538 DAINIGANGVCNATINAPFIAFTGLGESFKKVAAI---PWKICSNLKSALDYYCSNIMFR 594
Query 573 ISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGT----VYEKLKPVL 628
+ Y + D F L + +A + V++ + + GT L L
Sbjct 595 VFPYDIP-CDVNDFVELLLDCGKLTVA-TSYFVLRYLDEKFDTVLGTVSNACQTALSSFL 652
Query 629 DWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLAL 688
+ + F+ D +++ K + V A+ + VQ +++K + L
Sbjct 653 NACVAASRATAGFISDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLDIMSKAMKL 712
Query 689 CADSIIIGGAKLKALNL-GETFVTHSKGLYRKCVKSR-----EETGLLMPLKAPKEIIFL 742
++ G KL A+ G + + G Y C+ ++ ++ L++P K+ + +
Sbjct 713 LHTNVSWAGTKLSAIIYEGREALLFNSGTYF-CLSTKAKTLQDQMNLVLPGDYNKKTLGI 771
Query 743 -----EGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTE 797
+T+ + V + G L+P T+E + +VG V ++ + + D E
Sbjct 772 LDPVPNADTIDVTANSTVVDVVHGQLEP----TNEHGPSMIVGNYVLVSDKLFVRTDDEE 827
Query 798 KYCALAPNMMVTNNTFTLKGGAPT-KVTFGDDTVIEVQGYKSVNITFELDERIDKVL-NE 855
Y L N V + F LKGG P+ KVTFGD +EV Y+SV+IT+++ +D +L +
Sbjct 828 FYP-LCINGKVVSTLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPVLDALLSSS 886
Query 856 KCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFK 915
K + +TVE V +F V+ D V+ L P+ G D++++ Y++++ G+
Sbjct 887 KLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYVYNQDGDCA 946
Query 916 LASHMYCSFYP--------------------PDEDEEEGDCEE-EEFEPSTQYEYGTEDD 954
+S+M S P P D+EE EE P +
Sbjct 947 WSSNMTFSINPVEDVEEVEEFIEDDYLSDELPIADDEEAWTRAVEEVMPLDDILVAEIEL 1006
Query 955 YQGKPLEFGATSA-------------ALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTT 1001
+ PLE S ++ + QE DS + D
Sbjct 1007 EEDLPLETALESVEAEVGESISDELCVVETAKAQEPSVESTDSTPSTSTVVSENDLSVKP 1066
Query 1002 IQTIVEVQPQLEMEL---------------------TPVVQTIEVNSFSGYLKLTDNVYI 1040
+ + E LE+E Q V+S + ++N
Sbjct 1067 MSRVAETGDVLEVETAVVGGPVSDVTASVVTNDIVSVEQAQQCGVSSLPIQDEASENQVH 1126
Query 1041 ------------------------------------------------KNADIVEEAKKV 1052
D ++ A +
Sbjct 1127 QVPDLQCTSETKVEIVQPRQDLRPRRLRKSKVDLSKYKHTVINNSVTLVLGDAIQIASLL 1186
Query 1053 KPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAK 1112
V+VNAAN +LKHGGG+AGA+NKA+ +Q ESD+YI+ +GPL VG S +L G+ LA
Sbjct 1187 PKCVLVNAANRHLKHGGGIAGAINKASGGDVQEESDEYISNSGPLHVGDSVLLKGYGLAD 1246
Query 1113 HCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTN 1172
L VVGP+ ED LLK Y+ FN+H +++ PL+S+GIF DP S + V T
Sbjct 1247 AILRVVGPDARNNEDAALLKRCYKTFNKHTIVVTPLISSGIFSVDPKVSFEYLLANVTTT 1306
Query 1173 VYLAVFDKNLYDKLVS 1188
Y+ V ++++Y+ L +
Sbjct 1307 TYVVVNNEDIYNTLAT 1322
>sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus
(strain 2) OX=76344 GN=1a PE=3 SV=1
Length=4416
Score = 3643 bits (9447), Expect = 0.0, Method: Composition-based stats.
Identities = 1077/2979 (36%), Positives = 1615/2979 (54%), Gaps = 158/2979 (5%)
Query 1513 DWSYSGQ-STQLGIEFLKR----GDKSVYYTSNPTTFHLDG--EVITFDNLKTLLSLREV 1565
DW + + G+ +K G+ V + +G +V + ++ LL+
Sbjct 1500 DWRLVNKFDSVDGVRTVKYFECPGEIFVSSQGKKFGYVQNGSFKVASVSQIRALLA---- 1555
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ V TVD +N + V +G+ G + DG +VTK++ H+GK F+
Sbjct 1556 NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIHKGKVFFQYSGLS 1615
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A D L +Y + L KW + K ++NNCY+ A L LQ
Sbjct 1616 AADLVAVTDAFGFDEPQLLKYYNMLGMC-KWPVVVCGNYFAFKQSNNNCYINVACLMLQH 1674
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
+ LKF+ Q+A+ R+G+ F +L+LA + E D + M + + A+L
Sbjct 1675 LSLKFHKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDSTDFMRVVLREADLSGAT 1734
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
VCK CG +Q KGV+AVM+ GTL KG I CTCG + + Q PF+
Sbjct 1735 CDFEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLAKGYTIACTCGNKLV-HCTQLNVPFL 1792
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ +TG GHY H+ K D ++K SE KG TD
Sbjct 1793 ICSNKPEGKKLPDDV-VAANIFTGG-SLGHYTHVKCKPKYQLYDACNVSKVSEAKGNFTD 1850
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPN-- 1922
Y +N T + K T+ LD V C E +P L YY + Y+T +PI + +
Sbjct 1851 CLYLKNLKQTFSSKLTTFYLDDVKCVEYNPDLSQYYCESGKYYT-KPIIKAQFRTFEKVE 1909
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I A+ N G+ E K+T +P GDVV Y +
Sbjct 1910 GVYTNFKLVGHSI--AEKFNAKLGFDCNSPFTEYKITEWPTATGDVVLASDDLYVSRYSG 1967
Query 1982 GAKLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVETSNSFD-------VLKS 2030
G KP++W H + TY +P+ C ++ PV+ S D VL +
Sbjct 1968 GCVTFGKPVIWLGHEEASLKSLTYFNRPSVVC-ENKFNVLPVDVSEPTDKGPVPAAVLVT 2026
Query 2031 EDAQGM---DNLACEDLKPVSEEVVENP-------------TIQKDVLECNVKTTEVVGD 2074
G A E S+ VV+ +++ L K +V
Sbjct 2027 GALSGAATAPGTAKEQKVCASDSVVDQVVSGFLSDLSGATVDVKEVKLNGVKKPIKVEDS 2086
Query 2075 IILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVP 2134
+++ + K+ + + D+ ++ + NELSR++ T+
Sbjct 2087 VVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWMANELSRLVNSPTV------------ 2134
Query 2135 WDTIANYAKPFLNKVVSTTTNIVTRCLNR-------------VCTNYMPYFFTLLLQLCT 2181
Y K + K+V ++ R + C + + +FF
Sbjct 2135 ----REYVKWGMTKIVIPAKLVLLRDEKQEFVAPKVVKAKVIACYSAVKWFFLYCFSWIK 2190
Query 2182 FTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLI-----NIIIWF--L 2234
F N+ K T +A ++ + + S+ ++WF L
Sbjct 2191 F----NTDNKVIYTTEVASKLTFNLCCLAFKNALQTFNWNVVSRGFFLVATVFLLWFNFL 2246
Query 2235 LLSVCLGSLI---------YSTAALGVLMSNLGMPSYCTGYRE---GYLNSTNVTIATYC 2282
+V L + + + + G+ + C Y+ GY +S +C
Sbjct 2247 YANVILSDFYLPNIGFFPTFVGQIVAWVKTTFGIFTLCDLYQVSDVGYRSS-------FC 2299
Query 2283 TGSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLTAFGLVAEWFLAYILFTRFFY 2339
GS+ C +C SG D LD Y ++ +Q + SF + ++ F LV E + Y L+T FY
Sbjct 2300 NGSMVCELCFSGFDMLDNYDAINVVQHVVDRRVSFDY-ISLFKLVVELVIGYSLYTVCFY 2358
Query 2340 VLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY 2397
L MQL ++ F+ + W + + M P ++R YI + Y ++
Sbjct 2359 PLFGLIGMQLLTTWLPEFFMLETMHWSARFFVFVANMLPAFTLLRFYIVVTAMYKIFCLC 2418
Query 2398 VHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDT 2457
HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC+NC
Sbjct 2419 RHVMYGCSRPGCLFCYKRNRSVRVKCSTVVGGTLRYYDVMANGGTGFCAKHQWNCLNCSA 2478
Query 2458 FCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHS 2517
F G+TFI+ E A DLS + KRP+NPTD + Y+V V S+ L++++ GQ+ Y+ S
Sbjct 2479 FGPGNTFITHEAAADLSKELKRPVNPTDSAYYLVTEVKQVGCSMRLFYERDGQRVYDDVS 2538
Query 2518 LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALV 2577
S FV+++ L + KG +V+V + ++ +++ +A+V+Y+Q + +P+LL+++ L+
Sbjct 2539 ASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRPMLLVEKKLI 2596
Query 2578 SDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAA 2637
+ V+ MFD YV++ +V + L + V A L + V L+ V+ TFI A
Sbjct 2597 TTANTGLSVSQTMFDLYVDSLLGVLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFIGCA 2656
Query 2638 RQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSA 2696
R+ +DSDVETK + + + + + ++ T +SCNN + TY K + + DLG I +A
Sbjct 2657 RRKCAIDSDVETKSITKSIMSAVNAGVDFTDESCNNLVPTYVKSDTIVAADLGVLIQNNA 2716
Query 2697 RHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTT 2756
+H+ A VAK+ N+A IW+V F LS L+ ++R A K L KLT V ++TT
Sbjct 2717 KHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQEANVPILTT 2776
Query 2757 KIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGV 2816
+LKGG + + L+ L V L+ V + + P + + K +K ID GV
Sbjct 2777 PFSLKGGAVFSKVLQWLFVVNLICFIV---LWALMPTYAVHKSDMQLPLYASFKVIDNGV 2833
Query 2817 TRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTIL 2874
RD+ TD CFANK FD W+ G Y N +ACP++ AVI +++G+ + +P +L
Sbjct 2834 LRDVTVTDACFANKFIQFDQWYESTFGLVYYRNSRACPVVVAVIDQDIGYTLFNVPTKVL 2893
Query 2875 RTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCY 2934
R LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P PYCY
Sbjct 2894 RY-GFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHPYCY 2952
Query 2935 DTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
++ + Y+SL P RY L + + I+FP EG VR+V T YCR G CE +E
Sbjct 2953 TEGIMHNASLYDSLAPHVRYNLANSNGYIRFPEVVSEGIVRIVRTRSMTYCRVGLCEDAE 3012
Query 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
GVC + + WVLNN YYR++PG FCG +A +L+ + L++PI ++AS VAG I+
Sbjct 3013 EGVCFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALTASSVAGAIL 3072
Query 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
AI+V YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L +Y+ Y Y T
Sbjct 3073 AIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFYTT 3132
Query 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFS 3173
Y +++S + H+QW+VM+ ++P W I Y+ + + H W FS R++ S
Sbjct 3133 LYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFS--YCRKLGTEVRSDG 3190
Query 3174 TFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCH 3233
TFEE +L TF++ KE Y KL++ V +NRYL+LYNKY+YFSG MDT +YREAAC
Sbjct 3191 TFEEMSLTTFMITKESYCKLKNSV--SDVAFNRYLSLYNKYRYFSGKMDTAAYREAACSQ 3248
Query 3234 LAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG 3292
LAKA+ F+ N+G+DVLYQPP S+T++ LQSG KM FP+ KVE C+V VT G TLNG
Sbjct 3249 LAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVFPTSKVEPCVVSVTYGNMTLNG 3308
Query 3293 LWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKL 3352
LWLDD VYCPRHVIC+S DM +P+Y +LL R + +F V +G + L V+ + MQ +L L
Sbjct 3309 LWLDDKVYCPRHVICSSADMTDPDYSNLLCRVISSDFCVMSGRMSLTVMSYQMQGSLLVL 3368
Query 3353 KVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVG 3412
V NP TPKY F ++PG+TF+VLA YNG G + MR ++TIKGSFL GSCGSVG
Sbjct 3369 TVTLQNPNTPKYSFGVVKPGETFTVLAAYNGKSQGAFHVTMRSSYTIKGSFLCGSCGSVG 3428
Query 3413 FNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLY 3472
+ + D V F YMH +EL TG H GTD GNFYGP+ D Q Q D T TVNV+AWLY
Sbjct 3429 YVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAWLY 3488
Query 3473 AAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLK 3532
AA++N WF+ + +L +FN+ AM + + D V L L++ TG+ V + A++K
Sbjct 3489 AAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQILAAIK 3546
Query 3533 ELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLL 3592
L +G G+ ILGS +LEDE TP DV +Q +GV QS R +KGT W+L + L
Sbjct 3547 RLY-SGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVVKGTCCWILASTLLFCS 3605
Query 3593 VLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN- 3651
++ +W++F ++ + L + + +FAM+ VKHKH +L +F++P L T+ Y N
Sbjct 3606 IISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLVKHKHLYLTMFIMPVLCTLFYTNY 3664
Query 3652 MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTL 3711
+V S+ WL ++ + + + +V ++ +T R++ D ++ +
Sbjct 3665 LVVYKQSFRGLAYAWLSHFVPAVDYTYMDEVLYGVVLLVAMVFVTMRSINHDVFSVMFLV 3724
Query 3712 MNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFI 3771
+++LV Y+G L++ + ++ + S+ Y+ + A+ ++ + ++F
Sbjct 3725 GRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTWTTMLSLATAK-VIAKWLAVNVLYFT 3781
Query 3772 TGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPP 3831
++ ++L Y +GY C CY+G+ LLN FR+ LGVY+Y +S QE RYMN+ GL PP
Sbjct 3782 DVPQVKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISVQELRYMNANGLRPP 3841
Query 3832 KNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQC 3891
+NS +A LN KLLG+GG P I+V+ +QS+++DVKC +VVLL+ LQ L + SSSKLW C
Sbjct 3842 RNSFEALVLNFKLLGIGGVPVIEVSQIQSRLTDVKCVNVVLLNCLQHLHIASSSKLWQYC 3901
Query 3892 VQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQAIA 3945
LHN+IL D + AF+K+ LL VL + AVD I ++ ++ + + LQA+
Sbjct 3902 STLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDSTVLQALQ 3961
Query 3946 SEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKM 4004
SEF ++ S+ + A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ RKLE+M
Sbjct 3962 SEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKLERM 4021
Query 4005 ADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPL 4064
AD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 4022 ADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKLDNQALNSILDNAVKGCVPLNAIPS 4081
Query 4065 TTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAW 4124
T+ L +++PD + D TYA +W IQ + DAD + QL+EI + N+ W
Sbjct 4082 LTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQLNEIDV----NITW 4137
Query 4125 PLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVL 4182
PL++ A R N S+V LQNNEL P LR +G+ T YYNTT G+ V
Sbjct 4138 PLVIAANRHNEVSSVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQ--CYYNTTGMGKIVY 4195
Query 4183 ALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMV 4242
A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V
Sbjct 4196 AILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNTLARGWV 4254
Query 4243 LGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHT 4302
+G+L++TVRLQAG ATE +NS + S CAF+VD K Y DY+ GG P+TNCVKMLC H
Sbjct 4255 VGTLSSTVRLQAGTATEYASNSAIRSLCAFSVDPKKTYLDYIQQGGAPVTNCVKMLCDHA 4314
Query 4303 GTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVG 4362
GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV
Sbjct 4315 GTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-IKDPVS 4373
Query 4363 FTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
+ L + VC VCG W+ CSC QS D +FLN
Sbjct 4374 YVLTHDVCQVCGFWRDGSCSCVGT-GSQFQSKDT-NFLN 4410
Score = 601 bits (1549), Expect = 3e-170, Method: Composition-based stats.
Identities = 227/1099 (21%), Positives = 390/1099 (35%), Gaps = 194/1099 (18%)
Query 2 ESLVPGFNEKTHVQLS---LPVLQ-------VRDVLVRGFGDSVEEVLSEARQHLKDGTC 51
E G HV++ LP L+ +RD+ V + V + L+ G+
Sbjct 46 EPKTKGKTLINHVRVDCSRLPALECCVQSAIIRDIFV---DEDPLNVEASTMMALQFGSA 102
Query 52 GLVEVEK----------GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQY 97
LV+ K GVLP+ +F + T HV +L + +G+
Sbjct 103 VLVKPSKRLSIQAWAKLGVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCL 162
Query 98 GRSGETLGVLVPHVGEIPVAYRK------VLLRKNGNKGA---GGHSYGADLKSFDLGDE 148
G +G +G VP V IP ++ +LLRK GNKG+ G + +D E
Sbjct 163 G-NGRFIGWFVP-VTAIPAYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE 220
Query 149 LGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARA 208
D E+ N K+S L++ G ++D C G + L
Sbjct 221 ---DACEEVHLNPKGKYSRK-AYALLKGYRGVKSILFLDQYGCDYTGR----LAKGLEDY 272
Query 209 GKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKS-YELQTPFEIKLAKKF---- 263
G CTL E + ++E +AW+ +R ++ LQT I+
Sbjct 273 G--DCTLEEMKELFPVWCDSL---DNEVVVAWHVDRDPRAVMRLQTLATIRSIGYVGQPT 327
Query 264 -DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLS 318
D +G+ P + N+I+K + PR+ + L Y +C +
Sbjct 328 EDLVDGDVVVREPAHLLAANAIVKRL-PRLVETMLYTDSSVTEFCYKTK-LCDCGFITQF 385
Query 319 TLMKC--DHCGETSWQTGDFVKATCE-FCGTENLTKE-GATTCGYLPQNAVVKIYCPACH 374
+ C D C W G+ + C + E A + G +P+ V+
Sbjct 386 GYVDCCGDACDFRGWVPGNMMDGFLCPGCSKSYMPWELEAQSSGVIPKGGVL-------- 437
Query 375 NSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVF--SYVGCHNKCAYWVPRASANIG 432
+ + ++ G + FG V+ Y G W+P +++
Sbjct 438 ---------FTQSTDTVNRESFKLYGHAVVPFGSAVYWSPYPG------MWLPVIWSSVK 482
Query 433 C----NHTGVVGEGS-EGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAF 487
+TGVVG + D + L + V + G+ E+ AI+
Sbjct 483 SYADLTYTGVVGCKAIVQETDAICRSLYMDYVQ-HKCGNL---EQRAIL----------- 527
Query 488 VETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSI 547
GLD +Q++ + G++ + +L + F R+
Sbjct 528 -----GLDDVYHRQLLVNRGDYSL-----------------LLENVDLFVKR-----RAE 560
Query 548 FSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA-MMFTSDLA------TNNLVVMAY 600
F+ T + + L +LDG+ S LI + FTS + T+ + MA
Sbjct 561 FACKFATCGDGLVPL------LLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMAL 614
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRD------GWEIVKFIST 654
+ V++ ++++ + G + + K + + K E + D GW + ++
Sbjct 615 LFMHDVKVATKYVKKVTGKLAVRFKALGVAVVRKITEWFDLAVDTAASAAGWLCYQLVN- 673
Query 655 CACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII---IGGAKLKALNLGETFVT 711
V +T ++ E V+ F F + DS+ + G + +
Sbjct 674 -GLFAVANGGITFLSDVPELVKNFVDKFKVFFKVLIDSMSVSVLSGLTVVKTASNRVCLA 732
Query 712 HSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS 771
K +Y + + +MP+ E L GE P V + V + L
Sbjct 733 GCK-VYEVVQ--KRLSAYVMPVGCN-EATCLVGEIEPAVVEDDVVDVVKAPLT-----YQ 783
Query 772 EAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPN-MMVTNNTFTLKGGAPTKVTFGDDT- 829
+ P +C+ + + + Y + N + + A KV F D
Sbjct 784 GCCKPPTSFEKICVVDKLYMAKCGDQFYPVVVDNDTIGVLDQCWRFPCAGKKVEFNDKPK 843
Query 830 VIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE- 888
V E+ + + I F LD D VL++ CS + V+ ++E VV DAV TL P E
Sbjct 844 VKEIPSTRKIKINFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEH 903
Query 889 --LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ 946
+ T + L+ + YLFDE GE +A MYCSF PD++ DC + + +
Sbjct 904 DVIGTKVCALLNRLAEDYVYLFDEGGEEVIAPKMYCSFSAPDDE----DCVAADVVDADE 959
Query 947 YEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIV 1006
+ DD +A + QEED + Q V + D D V
Sbjct 960 NQGDDADD------------SAALVTDTQEEDGV-AKGQVGVAESDARLDQVEAFDIEKV 1006
Query 1007 EVQPQLEMELTPVVQTIEV 1025
E E+ +
Sbjct 1007 EDPILNELSAELNAPADKT 1025
Score = 187 bits (474), Expect = 5e-45, Method: Composition-based stats.
Identities = 66/252 (26%), Positives = 115/252 (46%), Gaps = 18/252 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV D+++ ++V V+VN AN + HG GVAGA+ KA + E+ D +
Sbjct 1266 CITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKSFIKETADMVK 1325
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHEVLLAPLLS 1150
G +VG +G NL K L++VGP+ + L+ AY++ N+ + ++ L+S
Sbjct 1326 NQGVCQVGECYESTGGNLCKTVLNIVGPDARGHGKQCYSFLERAYQHINKCDDVVTTLIS 1385
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + V NV L +K+ +D + + K + ++A+
Sbjct 1386 AGIFSVPTDVSLTYLIGVVTKNVILVSNNKDDFDVIEKCQVTSIAGTKALSLQLAKNLCR 1445
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+VK F T + S+ +C L+E + L ++ L ++ + +
Sbjct 1446 DVK-FETNACDSLFSD--------SCFVSSYDVLQEVELLRHDIQLDDDARVFVQAHMDN 1496
Query 1264 HPDSATLVSDID 1275
P LV+ D
Sbjct 1497 LPADWRLVNKFD 1508
Score = 45.8 bits (107), Expect = 0.025, Method: Composition-based stats.
Identities = 45/239 (19%), Positives = 82/239 (34%), Gaps = 28/239 (12%)
Query 1574 VDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDT-LRVEAF 1632
D + V S Q + D+ K++ +E P D T V AF
Sbjct 978 EDGVAKGQVGVAESDARLDQV-----EAFDIEKVEDPILNELSAELNAPADKTYEDVLAF 1032
Query 1633 EYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNP 1692
+ + L + + +K G S NC+L + L+ +Q + L+F
Sbjct 1033 DAIY---SEALSAFYAVPGDETHFKVC---GFYSPAIERTNCWLRSTLIVMQSLPLEFKD 1086
Query 1693 PALQDAYYRARAGEAANFCALILAYCNKTVGEL--GDVRETMSYLFQHANLDSCKRVLNV 1750
+Q + ++ F ++ K++ G V + + S K N
Sbjct 1087 LEMQKLWLSYKSSYNKEFVDKLVKSVPKSIILPQGGYVADFAYFFLSQ---CSFKAYANW 1143
Query 1751 VCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSA 1809
C C L+G++A+ + G + V C CG T L+ + P+ +
Sbjct 1144 RCLKCDM-DLKLQGLDAMFFYGDV--------VSHVCKCGTGMT--LLSADIPYTLHFG 1191
>sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronavirus
(strain JHM) OX=11144 GN=1a PE=1 SV=1
Length=4474
Score = 3640 bits (9440), Expect = 0.0, Method: Composition-based stats.
Identities = 1076/2981 (36%), Positives = 1615/2981 (54%), Gaps = 156/2981 (5%)
Query 1513 DWSYSGQ-STQLGIEFLKR----GDKSVYYTSNPTTFHLDG--EVITFDNLKTLLSLREV 1565
DW + + G+ +K G+ V + +G + + ++ LL+
Sbjct 1552 DWRLVNKFDSVDGVRTIKYFECPGEVFVSSQGKKFGYVQNGSFKEASVSQIRALLA---- 1607
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ V TVD +N + V +G+ G + DG +VTK++ H+GK F+
Sbjct 1608 NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIHKGKVFFQYSGLS 1667
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A + D L +Y S L KW + K ++NNCY+ A L LQ
Sbjct 1668 AADLAAVKDAFGFDEPQLLQYYSMLGMC-KWPVVVCGNYFAFKQSNNNCYINVACLMLQH 1726
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
+ LKF + R+G+ F +L+LA + E D + + + A+L
Sbjct 1727 LSLKFPKWQWRRPGNEFRSGKPLRFVSLVLAKGSFKFNEPSDSTDFIRVELREADLSGAT 1786
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
L +CK CG +Q KGV+AVM+ GTL KG I CTCG + + Q PF+
Sbjct 1787 CDLEFICK-CGVKQEQRKGVDAVMHFGTLDKSGLVKGYNIACTCGDKLV-HCTQFNVPFL 1844
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ +TG GHY H+ K D ++K SE KG TD
Sbjct 1845 ICSNTPEGKKLPDDV-VAANIFTGG-SVGHYTHVKCKPKYQLYDACNVSKVSEAKGNFTD 1902
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPN-- 1922
Y +N T + TY LD V C P L YY + Y+T +PI + +
Sbjct 1903 CLYLKNLKQTFSSVLTTYYLDDVKCVAYKPDLSQYYCESGKYYT-KPIIKAQFRTFEKVE 1961
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I A+ LN G+ E K+T +P GDVV Y +
Sbjct 1962 GVYTNFKLVGHDI--AEKLNAKLGFDCNSPFMEYKITEWPTATGDVVLASDDLYVSRYSG 2019
Query 1982 GAKLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVETSNSFD----------- 2026
G KP++W H + TY +P+ C ++ PV+ S D
Sbjct 2020 GCVTFGKPVIWRGHEEASLKSLTYFNRPSVVC-ENKFNVLPVDVSEPTDRRPVPSAVLVT 2078
Query 2027 ---------VLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVG---- 2073
+ +E + AC V +++V + V VK ++ G
Sbjct 2079 GAASGADASAISTEPGTAKEQKACAS-DSVEDQIVMEAQKKSSVTTVAVKEVKLNGVKKP 2137
Query 2074 -----DIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATH--- 2125
+++ + K+ + + D+ ++ + NELSR++ T+ +
Sbjct 2138 VKWNCSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWTANELSRLINSPTVREYVKW 2197
Query 2126 GLAAVNSVPWDTIAN--YAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFT 2183
G++ + +P + + + F+ V I C + +F F
Sbjct 2198 GMSKL-IIPANLLLLRDEKQEFVAPKVVKAKAIA-------CYGAVKWFLLYCFSWIKF- 2248
Query 2184 RSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLIN--------IIIWF-- 2233
N+ K T +A K K C A N L++ N+S + ++WF
Sbjct 2249 ---NTDNKVIYTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVFLLWFNF 2302
Query 2234 LLLSVCLGSL---------IYSTAALGVLMSNLGMPSYCTGYRE---GYLNSTNVTIATY 2281
L +V L ++ + + + G+ + C Y+ GY +S +
Sbjct 2303 LYANVILSDFYLPNIGPLPMFVGQIVAWVKTTFGVLTICDFYQVTDLGYRSS-------F 2355
Query 2282 CTGSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLTAFGLVAEWFLAYILFTRFF 2338
C GS+ C +C SG D LD Y S+ +Q + SF + ++ F LV E + Y L+T F
Sbjct 2356 CNGSMVCELCFSGFDMLDNYESINVVQHVVDRRVSFDY-ISLFKLVVELVIGYSLYTVCF 2414
Query 2339 YVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKS 2396
Y L + MQL ++ F+ + W L + + M P ++R YI + Y V+
Sbjct 2415 YPLFVLVGMQLLTTWLPEFFMLGTMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVYCL 2474
Query 2397 YVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCD 2456
HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC+NC+
Sbjct 2475 CRHVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLNCN 2534
Query 2457 TFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERH 2516
++ G+TFI+ E A DLS + KRP+NPTD + Y V V S+ L++++ GQ+ Y+
Sbjct 2535 SWKPGNTFITHEAAADLSKELKRPVNPTDSAYYSVIEVKQVGCSMRLFYERDGQRVYDDV 2594
Query 2517 SLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQAL 2576
S S FV+++ L + KG +V+V + ++ +++ +A+V+Y+Q + +P+L++++ L
Sbjct 2595 SASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRPMLMVEKKL 2652
Query 2577 VSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISA 2636
++ V+ MFD YV + +V + L + V A L + V L+ V+ TF+
Sbjct 2653 ITTANTGLSVSRTMFDLYVYSLLRHLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFVGC 2712
Query 2637 ARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCS 2695
AR+ +DSDVETK + + + + + +EVT +SCNN + TY K + + DLG I +
Sbjct 2713 ARRKCAIDSDVETKSITKSVMAAVNAGVEVTDESCNNLVPTYVKSDTIVAADLGVLIQNN 2772
Query 2696 ARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVT 2755
A+H+ + VAK+ N+A IW+V F LS L+ ++R A K L KLT V ++T
Sbjct 2773 AKHVQSNVAKAANVACIWSVDAFNQLSADLQHRLRKACVKTGLKIKLTYNKQEANVPILT 2832
Query 2756 TKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGG 2815
T +LKGG + + L+ L L+ V + + P + + K +K ID G
Sbjct 2833 TPFSLKGGAVFSRVLQWLFVANLICFIV---LWALMPTYAVHKSDMQLPLYASFKVIDNG 2889
Query 2816 VTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTI 2873
V RD++ TD CFANK FD W+ G Y N KACP++ AVI +++G + +P +
Sbjct 2890 VLRDVSVTDACFANKFNQFDQWYESTFGLVYYRNSKACPVVVAVIDQDIGHTLFNVPTKV 2949
Query 2874 LRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC 2933
LR LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P PYC
Sbjct 2950 LRY-GFHVLHFITHAFATDRVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHPYC 3008
Query 2934 YDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTCERS 2992
Y V+ + Y SL P RY L + I+FP EG VRVV T YCR G CE +
Sbjct 3009 YTEGVMHNASLYSSLVPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLCEEA 3068
Query 2993 EAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGI 3052
E G+C + + WVLNN YYR++PG FCG +A +L+ + L+QPI ++AS VAG I
Sbjct 3069 EEGICFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVQPIDFFALTASSVAGAI 3128
Query 3053 VAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYL 3112
+AI+V YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L +Y+ Y Y
Sbjct 3129 LAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFYT 3188
Query 3113 TFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSF 3172
T Y +++S + H+QW+VM+ ++P W I Y+ + + H W FS R++ + S
Sbjct 3189 TLYFPSEISVVMHLQWLVMYGAIMPLWFCITYVAVVVSNHALWLFS--YCRKIGTDVRSD 3246
Query 3173 STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACC 3232
TFEE AL TF++ KE Y KL++ V +NRYL+LYNKY+YFSG MDT +YREAAC
Sbjct 3247 GTFEEMALTTFMITKESYCKLKNSV--SDVAFNRYLSLYNKYRYFSGKMDTATYREAACS 3304
Query 3233 HLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLN 3291
LAKA+ F+ N+G+DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G TLN
Sbjct 3305 QLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCVVSVTYGNMTLN 3364
Query 3292 GLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLK 3351
GLWLDD VYCPRHVIC+S DM +P+Y +LL R ++ +F V + + L V+ + MQ +L
Sbjct 3365 GLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSDRMSLTVMSYQMQGSLLV 3424
Query 3352 LKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSV 3411
L V NP TPKY F ++PG+TF+VLA YNG P G + MR + TIKGSFL GSCGSV
Sbjct 3425 LTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVVMRSSHTIKGSFLCGSCGSV 3484
Query 3412 GFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWL 3471
G+ + D V F YMH +EL TG H GTD GNFYGP+ D Q Q D T TVNV+AWL
Sbjct 3485 GYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAWL 3544
Query 3472 YAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASL 3531
YAA++N WF+ + +L +FN+ AM + + D V L L++ TG+ V + A++
Sbjct 3545 YAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVLAAI 3602
Query 3532 KELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSL 3591
K L +G G+ ILGS +LEDE TP DV +Q +GV QS R IKGT W+L +
Sbjct 3603 KRL-HSGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTFLFC 3661
Query 3592 LVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN 3651
++ +W++F ++ + L + + FAM+ +KHKH +L ++++P L T+ Y N
Sbjct 3662 SIISAFVKWTMFMYVTTH-MLGVTLCALCFVIFAMLLIKHKHLYLTMYIMPVLCTLFYTN 3720
Query 3652 MVY--MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVW 3709
+ S+ WL ++ + + + +V ++ +T R++ D ++
Sbjct 3721 YLVVGYKQSFRGLAYAWLSYFVPAVDYTYMDEVLYGVVLLVAMVFVTMRSINHDVFSTMF 3780
Query 3710 TLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIF 3769
+ +++LV Y+G L++ + ++ + S+ Y+ + A+ ++ + ++
Sbjct 3781 LVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTWTTMLSLATAK-VIAKWLAVNVLY 3837
Query 3770 FITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL 3829
F ++ ++L Y +GY C CY+G+ LLN FR+ LGVY+Y +S QE RYMN+ GL
Sbjct 3838 FTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISVQELRYMNANGLR 3897
Query 3830 PPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA 3889
PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+SKLW
Sbjct 3898 PPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNSKLWQ 3957
Query 3890 QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQA 3943
C LHN+IL D + AF+K+ LL VL + AVD I ++ ++ + + LQA
Sbjct 3958 YCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNTVLQA 4017
Query 3944 IASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLE 4002
+ SEF ++ S+ + A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ RKLE
Sbjct 4018 LQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKLE 4077
Query 4003 KMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNII 4062
+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN I
Sbjct 4078 RMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAI 4137
Query 4063 PLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNL 4122
P T+ L +++PD + D TYA +W IQ + DAD + QL+EI +++
Sbjct 4138 PPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDVNS---- 4193
Query 4123 AWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRF 4180
WPL+++A R N S V LQNNEL P LR +G+ YYNTT G+
Sbjct 4194 TWPLVISANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNIPTQ--CYYNTTGTGKI 4251
Query 4181 VLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRG 4240
V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG
Sbjct 4252 VYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNTLARG 4310
Query 4241 MVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCT 4300
V+G+L++TVRLQAG ATE +NS +LS CAF+VD K Y DY+ GG P+TNCVKMLC
Sbjct 4311 WVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIQQGGVPVTNCVKMLCD 4370
Query 4301 HTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDP 4360
H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DP
Sbjct 4371 HAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-IKDP 4429
Query 4361 VGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
V + L + VC VCG W+ CSC QS D +FLN
Sbjct 4430 VSYVLTHDVCQVCGFWRDGSCSCVGT-GSQFQSKDT-NFLN 4468
Score = 622 bits (1605), Expect = 8e-177, Method: Composition-based stats.
Identities = 238/1127 (21%), Positives = 401/1127 (36%), Gaps = 209/1127 (19%)
Query 2 ESLVPGFNEKTHVQLS---LPVLQ-------VRDVLVRGFGDSVEEVLSEARQHLKDGTC 51
E V G HV++ LP L+ +RD+ V + ++V + L+ G+
Sbjct 46 EPKVKGKTLVNHVRVDCSRLPALECCVQSAIIRDIFV---DEDPQKVEASTMMALQFGSA 102
Query 52 GLVEVEK----------GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQY 97
LV+ K GVLP+ +F + T HV +L + +G+
Sbjct 103 VLVKPSKRLSVQAWAKLGVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCL 162
Query 98 GRSGETLGVLVPHVGEIPVAYRK------VLLRKNGNKGA---GGHSYGADLKSFDLGDE 148
G +G +G VP V IP ++ +LLRK GNKG+ G + +D E
Sbjct 163 G-NGRFIGWFVP-VTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE 220
Query 149 LGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARA 208
D E+ N K+S L+R G +VD C G C+ L
Sbjct 221 ---DACEEVHLNPRGKYSCK-AYALLRGYRGVKPILFVDQYGCDYTG----CLAKGLEDY 272
Query 209 GKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKS-YELQTPFEIKLAKKF---- 263
G TLSE + R ++E +AW+ +R ++ LQT ++ +
Sbjct 273 GDL--TLSEMKELSPVWRDSL---DNEVVVAWHVDRDPRAVMRLQTLATVRSIEYVGQPI 327
Query 264 -DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLS 318
D +G+ P + N+I+K + PR+ + L Y +C +
Sbjct 328 EDMVDGDVVMREPAHLLAPNAIVKRL-PRLVETMLYTDSSVTEFCYKTK-LCDCGFITQF 385
Query 319 TLMKC--DHCGETSWQTGDFVKATCE-FCGTENLTKE-GATTCGYLPQNAVVKIYCPACH 374
+ C D CG W G+ + C + E A + G +P+ V+
Sbjct 386 GYVDCCGDTCGFRGWVPGNMMDGFPCPGCCKSYMPWELEAQSSGVIPEGGVL-------- 437
Query 375 NSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVF--SYVGCHNKCAYWVPRASANIG 432
+ + ++ G + FGG + Y G W+P +++
Sbjct 438 ---------FTQSTDTVNRESFKLYGHAVVPFGGAAYWSPYPG------MWLPVIWSSVK 482
Query 433 C----NHTGVVGEGS-EGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAF 487
+TGVVG + D + L + V + G+ E+ AI+
Sbjct 483 SYSYLTYTGVVGCKAIVQETDAICRFLYMDYVQ-HKCGNL---EQRAIL----------- 527
Query 488 VETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSI 547
GLD +Q++ + G++ + +L + F R+
Sbjct 528 -----GLDDVYHRQLLVNRGDYSL-----------------LLENVDLFVKR-----RAE 560
Query 548 FSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA-MMFTSDLAT------NNLVVMAY 600
F+ T + + L +LDG+ S LI + FTS + + + MA
Sbjct 561 FACKFATCGDGLVPL------LLDGLVPRSYYLIKSGQAFTSLMVNFSREVVDMCMDMAL 614
Query 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRD------GWEIVKFIST 654
+ V++ ++++ + G V + K + + K E + D GW + ++
Sbjct 615 LFMHDVKVATKYVKKVTGKVAVRFKALGIAVVRKITEWFDLAVDTAASAAGWLCYQLVN- 673
Query 655 CACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII---IGGAKLKALNLGETFVT 711
V ++T +E+ E V+ F F + DS+ + G + +
Sbjct 674 -GLFAVANGVITFIQEVPELVKNFVDKFKTFFKVLIDSMSVSILSGLTVVKTASNRVCLA 732
Query 712 HSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS 771
SK +Y + +MP+ E L GE P + V + L
Sbjct 733 GSK-VYEVVQ--KSLPAYIMPVGC-SEATCLVGEIEPAVFEDDVVDVVKAPLT-----YQ 783
Query 772 EAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPN-MMVTNNTFTLKGGAPTKVTFGDDT- 829
+ P +CI + + + Y + N + + A KV F D
Sbjct 784 GCCKPPSSFEKICIVDKLYMAKCGDQFYPVVVDNDTVGVLDQCWRFPCAGKKVVFNDKPK 843
Query 830 VIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE- 888
V EV + + I F LD D VL++ CS + V+ ++E VV DAV TL P E
Sbjct 844 VKEVPSTRKIKIIFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEH 903
Query 889 --LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQ 946
+ T + L+ YLFDE GE +AS MYCSF PDED C + + +
Sbjct 904 GVIGTKVCALLERLVDDYVYLFDEGGEEVIASRMYCSFSAPDED-----CVATDVVYADE 958
Query 947 YEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWL------DDDSQQTVGQQDGSEDNQTT 1000
+ A + + QEED + DS+ V G E
Sbjct 959 NQD------------DDADDPVVLVADTQEEDGVAREQVDSADSEICVAHTGGQE----- 1001
Query 1001 TIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVE 1047
+ E + EV + + AD ++
Sbjct 1002 ----MTEPDVVGSQTPIASAEETEVGEACDREGIAEVKATVCADALD 1044
Score = 189 bits (481), Expect = 7e-46, Method: Composition-based stats.
Identities = 68/252 (27%), Positives = 117/252 (46%), Gaps = 18/252 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV D+++ ++V V+VN AN + HG GVAGA+ KA A E+ D +
Sbjct 1318 CITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKAFINETADMVK 1377
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLLS 1150
G +VGG +G L K L++VGP+ E LL+ AY++ N+ + ++ L+S
Sbjct 1378 AQGVCQVGGCYESTGGKLCKKVLNIVGPDARGHGNECYSLLERAYQHINKCDNVVTTLIS 1437
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + V NV L +++ +D + + K + ++A+
Sbjct 1438 AGIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFDVIEKCQVTSVAGTKALSFQLAKNLCR 1497
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+VK F+T + S+ ++ L+E + L ++ L ++ N +
Sbjct 1498 DVK-FVTNACSSLFS--------ESSFVSSYDVLQEVEALRHDIQLDDDARVFVQANMDC 1548
Query 1264 HPDSATLVSDID 1275
P LV+ D
Sbjct 1549 LPTDWRLVNKFD 1560
Score = 50.1 bits (118), Expect = 0.001, Method: Composition-based stats.
Identities = 34/144 (24%), Positives = 58/144 (40%), Gaps = 16/144 (11%)
Query 1663 GLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV 1722
G S NC+L + L+ +Q + L+F +Q + +AG F ++ K++
Sbjct 1109 GFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKLVKSAPKSI 1168
Query 1723 GEL--GDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFK 1780
G V + + S K N C CG + L+G++AV + G +
Sbjct 1169 ILPQGGYVADFAYFFLSQ---CSFKVHANWRCLKCGM-ELKLQGLDAVFFYGDV------ 1218
Query 1781 KGVQIPCTCGKQATKYLVQQESPF 1804
V C CG T L+ + P+
Sbjct 1219 --VSHMCKCGNSMT--LLSADIPY 1238
>sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronavirus
(strain A59) OX=11142 GN=1a PE=1 SV=1
Length=4468
Score = 3635 bits (9426), Expect = 0.0, Method: Composition-based stats.
Identities = 1080/2982 (36%), Positives = 1615/2982 (54%), Gaps = 165/2982 (6%)
Query 1513 DWSYSGQ-STQLGIEFLKR----GDKSVYYTSNPTTFHLDG--EVITFDNLKTLLSLREV 1565
DW + + G+ +K G V + +G + + ++ LL+
Sbjct 1553 DWRLVNKFDSVDGVRTIKYFECPGGIFVSSQGKKFGYVQNGSFKEASVSQIRALLA---- 1608
Query 1566 RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDD 1625
+ V TVD +N + V +G+ G + DG +VTK++ ++GK F+ +
Sbjct 1609 NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIYKGKVFFQYSDLS 1668
Query 1626 TLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQ 1685
+ A + D L +Y + L KW + K ++NNCY+ A L LQ
Sbjct 1669 EADLVAVKDAFGFDEPQLLKYYTMLGMC-KWPVVVCGNYFAFKQSNNNCYINVACLMLQH 1727
Query 1686 IELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCK 1745
+ LKF Q+A+ R+G+ F +L+LA + E D + M + + A+L
Sbjct 1728 LSLKFPKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDSIDFMRVVLREADLSGAT 1787
Query 1746 RVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFV 1805
L VCK CG +Q KGV+AVM+ GTL +G I CTCG + + Q PF+
Sbjct 1788 CNLEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLVRGYNIACTCGSKLV-HCTQFNVPFL 1845
Query 1806 MMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITD 1865
+ S P +L A+ +TG GHY H+ K D + K SE KG TD
Sbjct 1846 ICSNTPEGRKLPDDV-VAANIFTGG-SVGHYTHVKCKPKYQLYDACNVNKVSEAKGNFTD 1903
Query 1866 VFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP--N 1922
Y +N T + T+ LD V C E P L YY + Y+T +PI + + +
Sbjct 1904 CLYLKNLKQTFSSVLTTFYLDDVKCVEYKPDLSQYYCESGKYYT-KPIIKAQFRTFEKVD 1962
Query 1923 ASFDNFKFVCDNIKFADDLNQLTGYK-KPASRELKVTFFPDLNGDVVAIDYKHYTPSFKK 1981
+ NFK V +I A+ LN G+ E K+T +P GDVV Y +
Sbjct 1963 GVYTNFKLVGHSI--AEKLNAKLGFDCNSPFVEYKITEWPTATGDVVLASDDLYVSRYSS 2020
Query 1982 GAKLLHKPIVW--HVNNATNKATY--KPNTWCIRCLWSTKPVETSNSFD-------VLKS 2030
G KP+VW H + TY +P+ C ++ PV+ S D VL +
Sbjct 2021 GCITFGKPVVWLGHEEASLKSLTYFNRPSVVC-ENKFNVLPVDVSEPTDKGPVPAAVLVT 2079
Query 2031 E----DAQGMDNLACEDLKPVSEEVVENP-------------TIQKDVLECNVKTTEVVG 2073
DA +A E S V + +++ L K +V G
Sbjct 2080 GVPGADASAGAGIAKEQKACASASVEDQVVTEVRQEPSVSAADVKEVKLNGVKKPVKVEG 2139
Query 2074 DIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSV 2133
+++ + K+ + + D+ ++ + NELSR++ T+
Sbjct 2140 SVVVNDPTSETKVVKSLSIVDVYDMFLTGCKYVVWTANELSRLVNSPTV----------- 2188
Query 2134 PWDTIANYAKPFLNKVVSTTTNIVTRCLNR-------------VCTNYMPYFFTLLLQLC 2180
Y K + K+V+ ++ R + C + +F
Sbjct 2189 -----REYVKWGMGKIVTPAKLLLLRDEKQEFVAPKVVKAKAIACYCAVKWFLLYCFSWI 2243
Query 2181 TFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLIN--------IIIW 2232
F N+ K T +A K K C A N L++ N+S + ++W
Sbjct 2244 KF----NTDNKVIYTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVFLLW 2296
Query 2233 F--LLLSVCLGSLI---------YSTAALGVLMSNLGMPSYCTGYRE---GYLNSTNVTI 2278
F L +V L + + + G+ + C Y+ GY +S
Sbjct 2297 FNFLYANVILSDFYLPNIGPLPTFVGQIVAWFKTTFGVSTICDFYQVTDLGYRSS----- 2351
Query 2279 ATYCTGSIPCSVCLSGLDSLDTYPSLETIQITIS---SFKWDLTAFGLVAEWFLAYILFT 2335
+C GS+ C +C SG D LD Y ++ +Q + SF + ++ F LV E + Y L+T
Sbjct 2352 --FCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRLSFDY-ISLFKLVVELVIGYSLYT 2408
Query 2336 RFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYV 2393
FY L + MQL ++ F+ + W L + + M P ++R YI + Y V
Sbjct 2409 VCFYPLFVLIGMQLLTTWLPEFFMLETMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKV 2468
Query 2394 WKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCV 2453
+ HV+ GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC+
Sbjct 2469 YCLCRHVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCL 2528
Query 2454 NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTY 2513
NC+++ G+TFI+ E A DLS + KRP+NPTD + Y V V S+ L++++ GQ+ Y
Sbjct 2529 NCNSWKPGNTFITHEAAADLSKELKRPVNPTDSAYYSVTEVKQVGCSMRLFYERDGQRVY 2588
Query 2514 ERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLD 2573
+ + S FV+++ L + KG +V+V + ++ +++ A+V+Y+Q + +P+L+++
Sbjct 2589 DDVNASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLGAAVFYAQSLYRPMLMVE 2646
Query 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
+ L++ V+ MFD YV++ + +V + L + V A L + V L+ V+ TF
Sbjct 2647 KKLITTANTGLSVSRTMFDLYVDSLLNVLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTF 2706
Query 2634 ISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACI 2692
I AR+ +DSDVETK + + + + + ++ T +SCNN + TY K + + DLG I
Sbjct 2707 IGCARRKCAIDSDVETKSITKSVMSAVNAGVDFTDESCNNLVPTYVKSDTIVAADLGVLI 2766
Query 2693 DCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVN 2752
+A+H+ A VAK+ N+A IW+V F LS L+ ++R A K L KLT V
Sbjct 2767 QNNAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQEANVP 2826
Query 2753 VVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAI 2812
++TT +LKGG + + L+ L L+ V + + P + + K +K I
Sbjct 2827 ILTTPFSLKGGAVFSRMLQWLFVANLICFIV---LWALMPTYAVHKSDMQLPLYASFKVI 2883
Query 2813 DGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLP 2870
D GV RD++ TD CFANK FD W+ G Y N KACP++ AVI +++G + +P
Sbjct 2884 DNGVLRDVSVTDACFANKFNQFDQWYESTFGLAYYRNSKACPVVVAVIDQDIGHTLFNVP 2943
Query 2871 GTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPV 2930
T+LR LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P
Sbjct 2944 TTVLRY-GFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPH 3002
Query 2931 PYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDSEYCRHGTC 2989
PYCY V+ + Y SL P RY L + I+FP EG VRVV T YCR G C
Sbjct 3003 PYCYTGGVMHNASLYSSLAPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLC 3062
Query 2990 ERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVA 3049
E +E G+C + + WVLNN YYR++PG FCG +A +L+ + L++PI ++AS VA
Sbjct 3063 EEAEEGICFNFNRSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALTASSVA 3122
Query 3050 GGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIY 3109
G I+AI+V YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L +Y+ Y
Sbjct 3123 GAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFY 3182
Query 3110 LYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNG 3169
Y T Y +++S + H+QW+VM+ ++P W I Y+ + + H W FS R++
Sbjct 3183 FYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFS--YCRKIGTEV 3240
Query 3170 VSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREA 3229
S TFEE AL TF++ KE Y KL++ V +NRYL+LYNKY+YFSG MDT +YREA
Sbjct 3241 RSDGTFEEMALTTFMITKESYCKLKNSV--SDVAFNRYLSLYNKYRYFSGKMDTAAYREA 3298
Query 3230 ACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTT 3288
AC LAKA+ F+ N+G+DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G
Sbjct 3299 ACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCIVSVTYGNM 3358
Query 3289 TLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNC 3348
TLNGLWLDD VYCPRHVIC+S DM +P+Y +LL R ++ +F V +G + L V+ + MQ C
Sbjct 3359 TLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSGRMSLTVMSYQMQGC 3418
Query 3349 VLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSC 3408
L L V NP TPKY F ++PG+TF+VLA YNG P G + +R + TIKGSFL GSC
Sbjct 3419 QLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVTLRSSHTIKGSFLCGSC 3478
Query 3409 GSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVL 3468
GSVG+ + D V F YMH +EL TG H GTD GNFYGP+ D Q Q D T TVNV+
Sbjct 3479 GSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVV 3538
Query 3469 AWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMC 3528
AWLYAA+ N WF+ + +L +FN+ AM + + D V L L++ TG+ V +
Sbjct 3539 AWLYAAIFNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVL 3596
Query 3529 ASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTIL 3588
A++K L +G G+ ILGS +LEDE TP DV +Q +GV QS R IKGT W+L +
Sbjct 3597 AAIKRL-HSGFQGKQILGSCVLEDE-TPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTF 3654
Query 3589 TSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVA 3648
++ +W++F ++ + L + + +FAM+ +KHKH +L ++++P L T
Sbjct 3655 LFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLIKHKHLYLTMYIMPVLCTFY 3713
Query 3649 YFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRV 3708
+V S+ WL ++ + + + +V ++ +T R++ D +
Sbjct 3714 TNYLVVYKQSFRGLAYAWLSHFVPAVDYTYMDEVLYGVVLLVAMVFVTMRSINHDVFSIM 3773
Query 3709 WTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPI 3768
+ + +++LV Y+G L++ + ++ + S+ Y+ + A+ ++ + +
Sbjct 3774 FLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTWTTMLSLATAK-VIAKWLAVNVL 3830
Query 3769 FFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGL 3828
+F ++ ++L Y +GY C CY+G+ LLN FR+ LGVY+Y +S QE RYMN+ GL
Sbjct 3831 YFTDVPQIKLVLLSYLCIGYVCCCYWGILSLLNSIFRMPLGVYNYKISVQELRYMNANGL 3890
Query 3829 LPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLW 3888
PP+NS +A LN KLLG+GG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+SKLW
Sbjct 3891 RPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNSKLW 3950
Query 3889 AQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQ 3942
C LHN+IL D + AF+K+ LL VL + AVD I ++ ++ + + LQ
Sbjct 3951 QYCSTLHNEILATSDLSMAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNTVLQ 4010
Query 3943 AIASEFSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKL 4001
A+ SEF ++ S+ + A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ RKL
Sbjct 4011 ALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKL 4070
Query 4002 EKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNI 4061
E+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN
Sbjct 4071 ERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNA 4130
Query 4062 IPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPN 4121
IP T+ L +++PD + D TYA +W IQ + DAD + QL+EI +++
Sbjct 4131 IPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDVNS--- 4187
Query 4122 LAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGR 4179
WPL++ A R N S V LQNNEL P LR +G+ T YYNTT G+
Sbjct 4188 -TWPLVIAANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQ--CYYNTTGTGK 4244
Query 4180 FVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNR 4239
V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L R
Sbjct 4245 IVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNTLAR 4303
Query 4240 GMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLC 4299
G V+G+L++TVRLQAG ATE +NS +LS CAF+VD K Y DY+ GG P+TNCVKMLC
Sbjct 4304 GWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIKQGGVPVTNCVKMLC 4363
Query 4300 THTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCAND 4359
H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P D
Sbjct 4364 DHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-IKD 4422
Query 4360 PVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
PV + L + VC VCG W+ CSC QS D +FLN
Sbjct 4423 PVSYVLTHDVCQVCGFWRDGSCSCVGT-GSQFQSKDT-NFLN 4462
Score = 608 bits (1569), Expect = 1e-172, Method: Composition-based stats.
Identities = 234/1124 (21%), Positives = 405/1124 (36%), Gaps = 202/1124 (18%)
Query 2 ESLVPGFNEKTHVQLS---LPVLQ-------VRDVLVRGFGDSVEEVLSEARQHLKDGTC 51
E V G HV+++ LP L+ +RD+ V + ++V + L+ G+
Sbjct 46 EPKVKGKTLVNHVRVNCSRLPALECCVQSAIIRDIFV---DEDPQKVEASTMMALQFGSA 102
Query 52 GLVEVEK----------GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQY 97
LV+ K GVLP+ +F + T HV L + +G+
Sbjct 103 VLVKPSKRLSIQAWTNLGVLPKTAAMGLFKRVCLCNTRECSCDAHVAFHLFTVQPDGVCL 162
Query 98 GRSGETLGVLVPHVGEIPVAYRK------VLLRKNGNKGA---GGHSYGADLKSFDLGDE 148
G +G +G VP V IP ++ +LLRK GNKG+ G + +D E
Sbjct 163 G-NGRFIGWFVP-VTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVE 220
Query 149 LGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARA 208
D E+ N K+S L++ G +VD C G C+ L
Sbjct 221 ---DACEEVHLNPKGKYSCK-AYALLKGYRGVKPILFVDQYGCDYTG----CLAKGLEDY 272
Query 209 GKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKS-YELQTPFEIKLAKKFDTFN 267
G TLSE + R + E +AW+ +R ++ LQT ++
Sbjct 273 GDL--TLSEMKELFPVWRDSL---DSEVLVAWHVDRDPRAAMRLQTLATVRCIDYVGQPT 327
Query 268 GEC---------PNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLS 318
+ P + N+I+K + PR+ + L Y EC +
Sbjct 328 EDVVDGDVVVREPAHLLAANAIVKRL-PRLVETMLYTDSSVTEFCYKTK-LCECGFITQF 385
Query 319 TLMKC--DHCGETSWQTGDFVKATCE-FCGTENLTKE-GATTCGYLPQNAVVKIYCPACH 374
+ C D C W G+ + C + E A + G +P+ V+
Sbjct 386 GYVDCCGDTCDFRGWVAGNMMDGFPCPGCTKNYMPWELEAQSSGVIPEGGVL-------- 437
Query 375 NSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANI--- 431
+ + ++ G + FG V+ + C W+P +++
Sbjct 438 ---------FTQSTDTVNRESFKLYGHAVVPFGSAVY-WSPCPG---MWLPVIWSSVKSY 484
Query 432 -GCNHTGVVGEGS-EGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVE 489
G +TGVVG + D + L + V + G+ E+ AI+
Sbjct 485 SGLTYTGVVGCKAIVQETDAICRSLYMDYVQ-HKCGNL---EQRAIL------------- 527
Query 490 TVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSIFS 549
GLD +Q++ + G++ + +L + F R+ F+
Sbjct 528 ---GLDDVYHRQLLVNRGDYSL-----------------LLENVDLFVKR-----RAEFA 562
Query 550 RTLETAQNSVRVLQKAAITILDGISQYSLRLIDA-MMFTSDLA------TNNLVVMAYIT 602
T + + L +LDG+ S LI + FTS + T+ + MA +
Sbjct 563 CKFATCGDGLVPL------LLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMALLF 616
Query 603 GGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRD------GWEIVKFISTCA 656
V++ ++++ + G + + K + + K E + D GW + ++
Sbjct 617 MHDVKVATKYVKKVTGKLAVRFKALGVAVVRKITEWFDLAVDIAASAAGWLCYQLVN--G 674
Query 657 CEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII---IGGAKLKALNLGETFVTHS 713
V ++T +E+ E V+ F F + DS+ + G + + S
Sbjct 675 LFAVANGVITFVQEVPELVKNFVDKFKAFFKVLIDSMSVSILSGLTVVKTASNRVCLAGS 734
Query 714 KGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEA 773
K +Y + + +MP+ E L GE P + V + L
Sbjct 735 K-VYEVVQ--KSLSAYVMPVGC-SEATCLVGEIEPAVFEDDVVDVVKAPLT-----YQGC 785
Query 774 VEAPLVGTPVCINGLMLLEIKDTEKYCALAPN-MMVTNNTFTLKGGAPTKVTFGDDT-VI 831
+ P +CI + + + Y + N + + A KV F D V
Sbjct 786 CKPPTSFEKICIVDKLYMAKCGDQFYPVVVDNDTVGVLDQCWRFPCAGKKVEFNDKPKVR 845
Query 832 EVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE--- 888
++ + + ITF LD D VL++ CS + V+ ++E VV DAV TL P E
Sbjct 846 KIPSTRKIKITFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEHDV 905
Query 889 LLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYE 948
+ T + LD + YLFDE G+ +A MYCSF PD++ DC + + + +
Sbjct 906 IGTKVCALLDRLAGDYVYLFDEGGDEVIAPRMYCSFSAPDDE----DCVAADVVDADENQ 961
Query 949 YGTEDDYQGKPLEFGATSAALQPEEEQEED-----WLDDDSQQTVGQQDGSEDNQTTTIQ 1003
+D +A+ + QEED ++ DS+ V E+
Sbjct 962 DDDAED------------SAVLVADTQEEDGVAKGQVEADSEICVAHTGSQEE------- 1002
Query 1004 TIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVE 1047
+ E + EV S + + AD V+
Sbjct 1003 -LAEPDAVGSQTPIASAEETEVGEASDREGIAEAKATVCADAVD 1045
Score = 226 bits (576), Expect = 6e-57, Method: Composition-based stats.
Identities = 65/252 (26%), Positives = 116/252 (46%), Gaps = 18/252 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV D+++ + V V+VN AN + HG GVAGA+ + +A E+ D +
Sbjct 1319 CITPNVCFVKGDVIKVVRLVNAEVIVNPANGRMAHGAGVAGAIAEKAGSAFIKETSDMVK 1378
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHEVLLAPLLS 1150
G +VG +G L K L++VGP+ + LL+ AY++ N+ + ++ L+S
Sbjct 1379 AQGVCQVGECYESAGGKLCKKVLNIVGPDARGHGKQCYSLLERAYQHINKCDNVVTTLIS 1438
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + V NV L +++ +D + + K + ++A+
Sbjct 1439 AGIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFDVIEKCQVTSVAGTKALSLQLAKNLCR 1498
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+VK F+T + S+ ++C L+E + L ++ L ++ N +
Sbjct 1499 DVK-FVTNACSSLFS--------ESCFVSSYDVLQEVEALRHDIQLDDDARVFVQANMDC 1549
Query 1264 HPDSATLVSDID 1275
P LV+ D
Sbjct 1550 LPTDWRLVNKFD 1561
Score = 47.4 bits (111), Expect = 0.007, Method: Composition-based stats.
Identities = 32/149 (21%), Positives = 58/149 (39%), Gaps = 16/149 (11%)
Query 1663 GLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTV 1722
G S NC+L + L+ +Q + L+F +Q + +AG F ++ K++
Sbjct 1110 GFYSPAIERTNCWLRSTLIVMQSLPLEFKDLEMQKLWLSYKAGYDQCFVDKLVKSVPKSI 1169
Query 1723 GEL--GDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFK 1780
G V + + S K N C C + L+G++A+ + G +
Sbjct 1170 ILPQGGYVADFAYFFLSQ---CSFKAYANWRCLECDM-ELKLQGLDAMFFYGDV------ 1219
Query 1781 KGVQIPCTCGKQATKYLVQQESPFVMMSA 1809
V C CG T L+ + P+ +
Sbjct 1220 --VSHMCKCGNSMT--LLSADIPYTLHFG 1244
>sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=1a PE=3 SV=1
Length=4383
Score = 3533 bits (9160), Expect = 0.0, Method: Composition-based stats.
Identities = 1064/2917 (36%), Positives = 1623/2917 (56%), Gaps = 115/2917 (4%)
Query 1531 GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSM 1588
G + + G T +K L + + + TVD +N + V +
Sbjct 1530 GGIDICSQDKVFGYVQQGSFNKATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGE 1585
Query 1589 TYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMS 1648
++G+ G + DG +VTK K +++GK F+ N + ++A D L Y +
Sbjct 1586 SFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYN 1645
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAA 1708
L + KW+ + K A+NNC++ + L LQ + LKF Q+A+ R+G A
Sbjct 1646 MLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPA 1705
Query 1709 NFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAV 1768
F +L+LA G+ D R+ + +F +L + CK CG +Q GV+AV
Sbjct 1706 RFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAV 1764
Query 1769 MYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYT 1828
M+ GTLS E + G + C+CGK+ + V+ + PF++ S PA +L G + A+ +
Sbjct 1765 MHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLICSNTPASVKLPKGVGS-ANIFK 1822
Query 1829 GNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGV 1887
G+ + GHY H+ +++ D + + K ++ G ++D Y +N T TY LD V
Sbjct 1823 GD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDV 1881
Query 1888 VCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNASFDNFKFVCDNIKFADDLNQLTG 1946
E +P L YY Y+T++ I + + NFK + I D LN G
Sbjct 1882 KKIEYNPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGVYTNFKLIGHTI--CDILNAKLG 1939
Query 1947 YKKPA-SRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY 2003
+ E KVT +P GDVV Y +++G KP++W H + N TY
Sbjct 1940 FDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLTY 1999
Query 2004 KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLE 2063
++ + N FDVLK +D +++ D K E+ I L
Sbjct 2000 ----------FNRPLLVDENKFDVLKVDDVDDGGDISESDAK-------ESKEINIIKLS 2042
Query 2064 CNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTL- 2122
K +V +I+ + +K + + D+ ++ ++ N LS + + T+
Sbjct 2043 GVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLTGCRYVVRTANALSMAVNVPTIR 2102
Query 2123 --ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLC 2180
G+ V S+P D + + VV N ++ C N++ + F LL
Sbjct 2103 KFIKFGMTLV-SIPIDLLNLREIKPVFNVVKAVRNKIS-----ACFNFIKWLFVLLFGWI 2156
Query 2181 TFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINII--IWFLLLSV 2238
+ K T +A + + +F K ++ II I+ L +
Sbjct 2157 KISA----DNKVIYTTEVASKLTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNF 2212
Query 2239 CLGSLIYSTAALG--------------VLMSNLGMPSYCTGYREGYLNSTNVTIATYCTG 2284
++I+S L + S + + C Y + YC G
Sbjct 2213 IYANVIFSDFYLPKIGFLPTFVGKIAQWIKSTFSLVTICDLYSIQDVGF----KNQYCNG 2268
Query 2285 SIPCSVCLSGLDSLDTYPSLETIQITISS--FKWDLTAFGLVAEWFLAYILFTRFFYVLG 2342
SI C CL+G D LD Y +++ +Q F +V E ++Y L+T +FY L
Sbjct 2269 SIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF 2328
Query 2343 LAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
+Q+ ++ F+ ++ W + L+++L M P +R YI ASF ++ + HV
Sbjct 2329 ALISIQILTTWLPELFMLSTLHWSVRLLVSLANMLPAHVFMRFYIIIASFIKLFILFRHV 2388
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GC+ C+ CYKRNR+ RV+C+TIV G+ R + V ANGG GFC H WNC++CD++
Sbjct 2389 AYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKP 2448
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G+TFI+ E A DLS + KRPI PTD + + V V + L++++ GQ+TY+ + S
Sbjct 2449 GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFYERDGQRTYDDVNASL 2508
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FV+ NL + KG ++V+V + + ++++ +A+V+Y+Q + +PIL++D+ L++
Sbjct 2509 FVDYSNLLHSKVKGVPNMHVVVVENDA--DKANFLNAAVFYAQSLFRPILMVDKNLITTA 2566
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
V MFD YV+TF S F+V + L L+ATA + + + + VL TF+S AR+
Sbjct 2567 NTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQICKVLDTFLSCARKS 2626
Query 2641 F-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHI 2699
+DSDV+TK + + + + + +E+T +SCNN + TY K +N+ DLG I SA+H+
Sbjct 2627 CSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHV 2686
Query 2700 NAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIA 2759
VAK ++ IW+V F LS + +++ A K L KLT V+V+TT +
Sbjct 2687 QGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFS 2746
Query 2760 LKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRD 2819
LKGG + + ++ ++LV + + P + + K YK +D GV RD
Sbjct 2747 LKGGAVFSYFVYVCFLLSLVCFI---GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRD 2803
Query 2820 IASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILRTT 2877
++ D CFANK FD W+ G Y+N ACP++ AV+ +++G V +P +LR
Sbjct 2804 VSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACPIVVAVVDQDLGSTVFNVPTKVLRY- 2862
Query 2878 NGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTN 2937
LHF+ SA G CYTP I Y++F S CVL++ CT+F A G P PYCY
Sbjct 2863 GYHVLHFITHALSADGVQCYTPHSQISYSNFYASGCVLSSACTMFAMADGSPQPYCYTEG 2922
Query 2938 VLEGSVAYESLRPDTRYVLMDG-SIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGV 2996
+++ + Y SL P RY L + I+FP EG VR+V T YCR G CE ++ G+
Sbjct 2923 LMQNASLYSSLVPHVRYNLANAKGFIRFPEVLREGLVRIVRTRSMSYCRVGLCEEADEGI 2982
Query 2997 CVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIV 3056
C + +G WVLNNDYYRSLPG FCG D +L+ +F L QP+ L ++AS +AG I+A++
Sbjct 2983 CFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVI 3042
Query 3057 VTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYL 3116
V + YY ++ +RAFG+Y+ +V N +++ ++F +L + VY L VY++ Y Y T Y
Sbjct 3043 VVLVFYYLIKLKRAFGDYTSIVFVNVIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYF 3102
Query 3117 TNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE 3176
+++S + H+QW+VM+ ++P W + YI + + H +W F+ RR+ + S TFE
Sbjct 3103 PSEISVIMHLQWLVMYGTIMPLWFCLLYISVVVSNHAFWVFA--YCRRLGTSVRSDGTFE 3160
Query 3177 EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAK 3236
E AL TF++ K+ Y KL++ L +NRYL+LYNKY+Y+SG MDT +YREAAC LAK
Sbjct 3161 EMALTTFMITKDSYCKLKNS--LSDVAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAK 3218
Query 3237 ALNDF-SNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
A++ F +N+GSDVLYQPP S++++ LQSG KM P+ KVE C+V VT G TLNGLWL
Sbjct 3219 AMDTFTNNNGSDVLYQPPTASVSTSFLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWL 3278
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVD 3355
DD VYCPRHVIC++ DM NP+Y +LL R ++ +F V + L V+ + MQ C+L L V
Sbjct 3279 DDKVYCPRHVICSASDMTNPDYTNLLCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVT 3338
Query 3356 TANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNI 3415
N +TPKY F ++PG+TF+VLA YNG P G + MR ++TIKGSFL GSCGSVG+ +
Sbjct 3339 LQNSRTPKYTFGVVKPGETFTVLAAYNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVL 3398
Query 3416 DYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAV 3475
DCV F YMH +EL TG H GTD G+FYGP+ D Q Q D +VN +AWLYAA+
Sbjct 3399 MGDCVKFVYMHQLELSTGCHTGTDFNGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAI 3458
Query 3476 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL 3535
+N WF+ ++ DFN+ A+ + + D V + L++ TG+++ + A++K L
Sbjct 3459 LNNCNWFVQSDKCSVEDFNVWALSNGFSQVKSDLV--IDALASMTGVSLETLLAAIKRL- 3515
Query 3536 QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLV 3595
+NG GR I+GS EDE TP DV +Q +G+ QS R +KG W++ + ++
Sbjct 3516 KNGFQGRQIMGSCSFEDELTPSDVYQQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIIT 3575
Query 3596 QSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN-MVY 3654
+W++F ++ N L + + + AM+ VKHKH +L ++++P L T+ Y N +V
Sbjct 3576 AFVKWTMFMYVTTN-MLSITFCALCVISLAMLLVKHKHLYLTMYIIPVLFTLLYNNYLVV 3634
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL-LILMTARTVYDDGARRVWTLMN 3713
++ + WL S+ + D V+Y +++ ++ +T R++ D + +
Sbjct 3635 YKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGMLLLIGMVFVTLRSINHDLFSFIMFVGR 3693
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+++V Y G+ L++ I + ++ S+ Y+ M A+ ++ V ++F
Sbjct 3694 VISVVSLWYMGSNLEEEILL--MLASLFGTYTWTTALSMAAAK-VIAKWVAVNVLYFTDI 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
++ +++ Y F+GY +CY+GLF L+N FR+ LGVY+Y +S QE RYMN+ GL PPKN
Sbjct 3751 PQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKN 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
S +A LN KLLG+GG P I+V+ QSK++DVKC +VVLL+ LQ L V S+SKLW C
Sbjct 3811 SFEALMLNFKLLGIGGVPIIEVSQFQSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCST 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQAIASE 3947
LHN+IL D AFEK+ LL VL + AVD I ++C++ + LQA+ SE
Sbjct 3871 LHNEILATSDLGVAFEKLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSE 3930
Query 3948 FSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMAD 4006
F ++ S+ + A++ ++A ++G + + LK+L+K+ N+AKS ++RD A+ RKLE+MAD
Sbjct 3931 FVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAYERDRAVARKLERMAD 3990
Query 4007 QAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTT 4066
A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 3991 LALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLA 4050
Query 4067 AAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPL 4126
A L +++PD + Y D TYA +W+IQ + D+D QL+EIS D + WPL
Sbjct 4051 ANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN----WPL 4106
Query 4127 IVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLAL 4184
++ A R N SA LQNNEL P L+ +G QT T YYN + G+ V A+
Sbjct 4107 VIIANRHNEVSATVLQNNELMPAKLKTQVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAI 4164
Query 4185 LSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLG 4244
LSD+ LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V+G
Sbjct 4165 LSDVDGLKYTKILKDDGN-FVVLELDPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVG 4223
Query 4245 SLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGT 4304
++++TVRLQAG ATE +NS++LS CAF+VD K Y D++ GG PI NCVKMLC H GT
Sbjct 4224 TISSTVRLQAGTATEYASNSSILSLCAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGT 4283
Query 4305 GQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFT 4364
G AITV P+A +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV +
Sbjct 4284 GMAITVKPDATTNQDSYGGASVCIYCRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYV 4342
Query 4365 LKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
L + VC VCG W+ CSC + +QS D +FLN
Sbjct 4343 LTHDVCQVCGFWRDGSCSCVST-DTTVQSKDT-NFLN 4377
Score = 655 bits (1691), Expect = 0.0, Method: Composition-based stats.
Identities = 227/1040 (22%), Positives = 379/1040 (36%), Gaps = 183/1040 (18%)
Query 43 RQHLKDGTCGLVEVE----------KGVLPQLEQPYVFIKRSDA---RTAPHGHVMVEL- 88
+ L+ LV +G P +F +RS R A + HV +L
Sbjct 94 QDALQSREAVLVTPPLGMSLEACYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAYQLY 153
Query 89 VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKNGNKGA-------GGHS 135
+ + G+ +G +G+ +G ++P + +PV RK + LRK G KGA GG
Sbjct 154 MIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVPWVMYLRKCGEKGAYNKDHKRGGFE 211
Query 136 YGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
+ + K D D + +P F + L+R G YVD C G
Sbjct 212 HVYNFKVEDAYDLVHDEPKGKFSKK---------AYALIRGYRGVKPLLYVDQYGCDYTG 262
Query 196 ---YPLECIKDLLARAGKASCTL-SEQLDFIDTKRGVYCCREHEHEIAWYTERSEK-SYE 250
LE D + KA + S++L F + +AW+ R +
Sbjct 263 GLADGLEAYADKTLQEMKALFPIWSQELPF-------------DVTVAWHVVRDPRYVMR 309
Query 251 LQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFM---- 297
LQ+ I+ D +G P V+ +SII + + L M
Sbjct 310 LQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYADDSII------LRQHNLVDIMSCFY 363
Query 298 ----GRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCEF-CGTENLT 350
+ + Y V +C + + C D C W G+ + CG T
Sbjct 364 MEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCDFKGWVPGNMIDGFACTTCGHVYET 422
Query 351 KEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGC 409
+ A + G LP N V+ A + G + S Y G + FGGC
Sbjct 423 GDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFTLY------------GQTVVYFGGC 469
Query 410 VFSYVGCHNKCAYWVPRASANI----GCNHTGVVGEGSEGLNDNL-LEILQKEKVNINIV 464
V+ + N W+P +++ G +TGVVG + NL + L + V +
Sbjct 470 VY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGCKAIVKETNLICKALYLDYVQ-HKC 524
Query 465 GDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNI- 523
G+ E + + S L+ +K ++E+ F + + K + +
Sbjct 525 GNLHQRELLGV---------SDVWHKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVC 575
Query 524 --GEQKSILSPLY-----------AFASEAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
G +L L AF A ++ ++ S++ E S+ L AAI L
Sbjct 576 ADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKICHAVVSKSKELLDVSLDSLS-AAIHYL 634
Query 571 DGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDW 630
+ +++D SD T+ +V + T+ L VL
Sbjct 635 NS------KIVDLAQHFSDFGTS-------FVSKIVHFFKTFTTSTALAFAWVLFHVLHG 681
Query 631 LEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCA 690
+ + F+++ I ++ S V + AK + +S++ F +
Sbjct 682 AYIVVESDIYFVKN---IPRYASA-----VAQAFRSVAKVVLDSLRVTFIDGLSCFKIGR 733
Query 691 DSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMP---LKAPKEIIFLEGETL 747
I + G+K+ + G + HS L + L MP KA ++ I+L+G
Sbjct 734 RRICLSGSKIYEVERG---LLHSSQL------PLDVYDLTMPSQVQKAKQKPIYLKGSGS 784
Query 748 PTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMM 807
+ V + T L P E P V +CI + + + Y + +
Sbjct 785 DFSLADSVVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDGHV 839
Query 808 VTNNTFTLKGGAPTKVTFGDDT-VIEVQGY-KSVNITFELDERIDKVLNEKCSAYTVELG 865
+ A +VTF + V E+ K++ + +ELD+ + +LN C + V+
Sbjct 840 GLLDQAWRVPCAGRRVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGVFEVDDT 899
Query 866 TEVNEFACVVADAVIKTLQPVSEL---LTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
++ EF VV DA+ + L P EL + L + + +LFDE+GE LAS +YC
Sbjct 900 VDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGEEVLASKLYC 959
Query 923 SFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQE--EDWL 980
+F P++D D EE E D G A + EE E ED L
Sbjct 960 AFTAPEDD----DFLEESGVEEDDVEGEETD---LTVTSAGEPCVASEQEESSEILEDTL 1012
Query 981 DDDSQQTVGQQDGSEDNQTT 1000
DD ED + +
Sbjct 1013 DDGPCVETSDSQVEEDVEMS 1032
Score = 194 bits (492), Expect = 3e-47, Method: Composition-based stats.
Identities = 59/251 (24%), Positives = 110/251 (44%), Gaps = 17/251 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D +
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + T V L ++ +D + ++ K++ ++++
Sbjct 1392 AGIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFDLISKCQITAVEGTKKLAERLSFNVGR 1451
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+ +K + L++ L ++ L ++ N ++
Sbjct 1452 SIVYETDANKLILSNDVA--------FVSTFNVLQDVLSLRHDIALDDDARTFVQSNVDV 1503
Query 1264 HPDSATLVSDI 1274
P+ +V+
Sbjct 1504 VPEGWRVVNKF 1514
Score = 48.9 bits (115), Expect = 0.002, Method: Composition-based stats.
Identities = 41/196 (21%), Positives = 73/196 (37%), Gaps = 22/196 (11%)
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
++ +V L K NNC+L + L +Q++ +F LQD + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1717 Y--CNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
N V + G V + + L + V C C LKG++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1775 SYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCG 1834
V C CG+ L+ + PF A + LK F Y+
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPFT------AHFALKDKLFCAFITKRSVYKAA 1216
Query 1835 HYKHITSKETLYCIDG 1850
+ ++ +DG
Sbjct 1217 CVVDVNDSHSMAVVDG 1232
>sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=1a PE=3 SV=1
Length=4383
Score = 3531 bits (9156), Expect = 0.0, Method: Composition-based stats.
Identities = 1064/2917 (36%), Positives = 1622/2917 (56%), Gaps = 115/2917 (4%)
Query 1531 GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSM 1588
G + + G T +K L + + + TVD +N + V +
Sbjct 1530 GGIDICSQDKVFGYVQQGSFNKATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGE 1585
Query 1589 TYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMS 1648
+G+ G + DG +VTK K +++GK F+ N + ++A D L Y +
Sbjct 1586 NFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYN 1645
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAA 1708
L + KW+ + K A+NNC++ + L LQ + LKF Q+A+ R+G A
Sbjct 1646 MLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPA 1705
Query 1709 NFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAV 1768
F +L+LA G+ D R+ + +F +L + CK CG +Q GV+AV
Sbjct 1706 RFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAV 1764
Query 1769 MYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYT 1828
M+ GTLS E + G + C+CGK+ + V+ + PF++ S PA +L G + A+ +
Sbjct 1765 MHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLICSNTPASVKLPKGVGS-ANIFK 1822
Query 1829 GNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGV 1887
G+ + GHY H+ +++ D + + K ++ G ++D Y +N T TY LD V
Sbjct 1823 GD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDV 1881
Query 1888 VCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNASFDNFKFVCDNIKFADDLNQLTG 1946
E P L YY Y+T++ I + + NFK + I D LN G
Sbjct 1882 KKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGVYTNFKLIGHTI--CDILNAKLG 1939
Query 1947 YKKPA-SRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY 2003
+ E KVT +P GDVV Y +++G KP++W H + N TY
Sbjct 1940 FDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLTY 1999
Query 2004 KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLE 2063
++ + N FDVLK +D +++ D K E+ I L
Sbjct 2000 ----------FNRPLLVDENKFDVLKVDDVDDGGDISESDAK-------ESKEINIIKLS 2042
Query 2064 CNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTL- 2122
K +V +I+ + +K + + D+ ++ ++ N+LS + + T+
Sbjct 2043 GVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLTGCRYVVRTANDLSMAVNVPTIR 2102
Query 2123 --ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLC 2180
G+ V S+P D + + VV N ++ C N++ + F LL
Sbjct 2103 KFIKFGMTLV-SIPIDLLNLREIKPVFNVVKAVRNKIS-----ACFNFIKWLFVLLFGWI 2156
Query 2181 TFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINII--IWFLLLSV 2238
+ K T +A + + +F K ++ II I+ L +
Sbjct 2157 KISA----DNKVIYTTEVASKLTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNF 2212
Query 2239 CLGSLIYSTAALG--------------VLMSNLGMPSYCTGYREGYLNSTNVTIATYCTG 2284
++I+S L + S + + C Y + YC G
Sbjct 2213 IYANVIFSDFYLPKIGFLPTFVGKIAQWIKSTFSLVTICDLYSIQDVGF----KNQYCNG 2268
Query 2285 SIPCSVCLSGLDSLDTYPSLETIQITISS--FKWDLTAFGLVAEWFLAYILFTRFFYVLG 2342
SI C CL+G D LD Y +++ +Q F +V E ++Y L+T +FY L
Sbjct 2269 SIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF 2328
Query 2343 LAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
+Q+ ++ F+ ++ W + L+++L M P +R YI ASF ++ + HV
Sbjct 2329 ALISIQILTTWLPELFMLSTLHWSVRLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHV 2388
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GC+ C+ CYKRNR+ RV+C+TIV G+ R + V ANGG GFC H WNC++CD++
Sbjct 2389 AYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKP 2448
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G+TFI+ E A DLS + KRPI PTD + + V V + L++++ GQ+TY+ + S
Sbjct 2449 GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFYERDGQRTYDDVNASL 2508
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FV+ NL + KG ++V+V + + ++++ +A+V+Y+Q + +PIL++D+ L++
Sbjct 2509 FVDYSNLLHSKVKGVPNMHVVVVENDA--DKANFLNAAVFYAQSLFRPILMVDKNLITTA 2566
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
V MFD YV+TF S F+V + L L+ATA + + + + VL TF+S AR+
Sbjct 2567 NTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQICKVLDTFLSCARKS 2626
Query 2641 F-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHI 2699
+DSDV+TK + + + + + +E+T +SCNN + TY K +N+ DLG I SA+H+
Sbjct 2627 CSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHV 2686
Query 2700 NAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIA 2759
VAK ++ IW+V F LS + +++ A K L KLT V+V+TT +
Sbjct 2687 QGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFS 2746
Query 2760 LKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRD 2819
LKGG + + ++ ++LV + + P + + K YK +D GV RD
Sbjct 2747 LKGGAVFSYFVYVCFLLSLVCFI---GLWCLMPTYTVHKSDFQLPVYTSYKVLDNGVIRD 2803
Query 2820 IASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILRTT 2877
++ D CFANK FD W+ G Y+N ACP++ AV+ +++G V +P +LR
Sbjct 2804 VSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACPIVVAVVDQDLGSTVFNVPTKVLRY- 2862
Query 2878 NGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTN 2937
LHF+ SA G CYTP I Y++F S CVL++ CT+F A G P PYCY
Sbjct 2863 GYHVLHFITHALSADGVQCYTPHSQISYSNFYASGCVLSSACTMFAMADGSPQPYCYTEG 2922
Query 2938 VLEGSVAYESLRPDTRYVLMDG-SIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGV 2996
+++ + Y SL P RY L + I+FP EG VR+V T YCR G CE ++ G+
Sbjct 2923 LMQNASLYSSLVPHVRYNLANAKGFIRFPEVLREGLVRIVRTRSMSYCRVGLCEEADEGI 2982
Query 2997 CVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIV 3056
C + +G WVLNNDYYRSLPG FCG D +L+ +F L QP+ L ++AS +AG I+A++
Sbjct 2983 CFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVI 3042
Query 3057 VTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYL 3116
V + YY ++ +RAFG+Y+ +V N +++ ++F +L + VY L VY++ Y Y T Y
Sbjct 3043 VVLVFYYLIKLKRAFGDYTSIVFVNVIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYF 3102
Query 3117 TNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE 3176
+++S + H+QW+VM+ ++P W + YI + + H +W F+ RR+ + S TFE
Sbjct 3103 PSEISVIMHLQWLVMYGTIMPLWFCLLYISVVVSNHAFWVFA--YCRRLGTSVRSDGTFE 3160
Query 3177 EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAK 3236
E AL TF++ K+ Y KL++ L +NRYL+LYNKY+Y+SG MDT +YREAAC LAK
Sbjct 3161 EMALTTFMITKDSYCKLKNS--LSDVAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAK 3218
Query 3237 ALNDF-SNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
A++ F +N+GSDVLYQPP S++++ LQSG KM P+ KVE C+V VT G TLNGLWL
Sbjct 3219 AMDTFTNNNGSDVLYQPPTASVSTSFLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWL 3278
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVD 3355
DD VYCPRHVIC++ DM NP+Y +LL R ++ +F V + L V+ + MQ C+L L V
Sbjct 3279 DDKVYCPRHVICSASDMTNPDYTNLLCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVT 3338
Query 3356 TANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNI 3415
N +TPKY F ++PG+TF+VLA YNG P G + MR ++TIKGSFL GSCGSVG+ +
Sbjct 3339 LQNSRTPKYTFGVVKPGETFTVLAAYNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVL 3398
Query 3416 DYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAV 3475
DCV F YMH +EL TG H GTD G+FYGP+ D Q Q D +VN +AWLYAA+
Sbjct 3399 MGDCVKFVYMHQLELSTGCHTGTDFNGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAI 3458
Query 3476 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL 3535
+N WF+ ++ DFN+ A+ + + D V + L++ TG+++ + A++K L
Sbjct 3459 LNNCNWFVQSDKCSVEDFNVWALSNGFSQVKSDLV--IDALASMTGVSLETLLAAIKRL- 3515
Query 3536 QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLV 3595
+NG GR I+GS EDE TP DV +Q +G+ QS R +KG W++ + ++
Sbjct 3516 KNGFQGRQIMGSCSFEDELTPSDVYQQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIIT 3575
Query 3596 QSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN-MVY 3654
+W++F ++ N L + + + AM+ VKHKH +L ++++P L T+ Y N +V
Sbjct 3576 AFVKWTMFMYVTTN-MLSITFCALCVISLAMLLVKHKHLYLTMYIIPVLFTLLYNNYLVV 3634
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL-LILMTARTVYDDGARRVWTLMN 3713
++ + WL S+ + D V+Y +++ ++ +T R++ D + +
Sbjct 3635 YKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGMLLLIGMVFVTLRSINHDLFSFIMFVGR 3693
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+++V Y G+ L++ I + ++ S+ Y+ M A+ ++ V ++F
Sbjct 3694 VISVVSLWYMGSNLEEEILL--MLASLFGTYTWTTALSMAAAK-VIAKWVAVNVLYFTDI 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
++ +++ Y F+GY +CY+GLF L+N FR+ LGVY+Y +S QE RYMN+ GL PPKN
Sbjct 3751 PQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKN 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
S +A LN KLLG+GG P I+V+ QSK++DVKC +VVLL+ LQ L V S+SKLW C
Sbjct 3811 SFEALMLNFKLLGIGGVPIIEVSQFQSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCST 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQAIASE 3947
LHN+IL D AFEK+ LL VL + AVD I ++C++ + LQA+ SE
Sbjct 3871 LHNEILATSDLGVAFEKLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSE 3930
Query 3948 FSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMAD 4006
F ++ S+ + A++ ++A ++G + + LK+L+K+ N+AKS ++RD A+ RKLE+MAD
Sbjct 3931 FVNMASFVEYEVAKKNLDEARSSGSANQQQLKQLEKACNIAKSAYERDRAVARKLERMAD 3990
Query 4007 QAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTT 4066
A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 3991 LALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLA 4050
Query 4067 AAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPL 4126
A L +++PD + Y D TYA +W+IQ + D+D QL+EIS D + WPL
Sbjct 4051 ANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN----WPL 4106
Query 4127 IVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLAL 4184
++ A R N SA LQNNEL P L+ +G QT T YYN + G+ V A+
Sbjct 4107 VIIANRHNEVSATVLQNNELMPAKLKTQVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAI 4164
Query 4185 LSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLG 4244
LSD+ LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V+G
Sbjct 4165 LSDVDGLKYTKILKDDGN-FVVLELDPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVG 4223
Query 4245 SLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGT 4304
++++TVRLQAG ATE +NS++LS CAF+VD K Y D++ GG PI NCVKMLC H GT
Sbjct 4224 TISSTVRLQAGTATEYASNSSILSLCAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGT 4283
Query 4305 GQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFT 4364
G AITV P+A +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV +
Sbjct 4284 GMAITVKPDATTNQDSYGGASVCIYCRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYV 4342
Query 4365 LKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
L + VC VCG W+ CSC + +QS D +FLN
Sbjct 4343 LTHDVCQVCGFWRDGSCSCVST-DTTVQSKDT-NFLN 4377
Score = 655 bits (1689), Expect = 0.0, Method: Composition-based stats.
Identities = 227/1040 (22%), Positives = 379/1040 (36%), Gaps = 183/1040 (18%)
Query 43 RQHLKDGTCGLVEVE----------KGVLPQLEQPYVFIKRSDA---RTAPHGHVMVEL- 88
+ L+ LV +G P +F +RS R A + HV +L
Sbjct 94 QDALQSREAVLVTPPLGMSLEACYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAYQLY 153
Query 89 VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKNGNKGA-------GGHS 135
+ + G+ +G +G+ +G ++P + +PV RK + LRK G KGA GG
Sbjct 154 MIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVPWVMYLRKCGEKGAYNKDHKRGGFE 211
Query 136 YGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
+ + K D D + +P F + L+R G YVD C G
Sbjct 212 HVYNFKVEDAYDLVHDEPKGKFSKK---------AYALIRGYRGVKPLLYVDQYGCDYTG 262
Query 196 ---YPLECIKDLLARAGKASCTL-SEQLDFIDTKRGVYCCREHEHEIAWYTERSEK-SYE 250
LE D + KA + S++L F + +AW+ R +
Sbjct 263 GLADGLEAYADKTLQEMKALFPIWSQELPF-------------DVTVAWHVVRDPRYVMR 309
Query 251 LQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFM---- 297
LQ+ I+ D +G P V+ +SII + + L M
Sbjct 310 LQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYADDSII------LRQHNLVDIMSCFY 363
Query 298 ----GRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCEF-CGTENLT 350
+ + Y V +C + + C D C W G+ + CG T
Sbjct 364 MEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCDFKGWVPGNMIDGFACTTCGHVYET 422
Query 351 KEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGC 409
+ A + G LP N V+ A + G + S Y G + FGGC
Sbjct 423 GDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFTLY------------GQTVVYFGGC 469
Query 410 VFSYVGCHNKCAYWVPRASANI----GCNHTGVVGEGSEGLNDNL-LEILQKEKVNINIV 464
V+ + N W+P +++ G +TGVVG + NL + L + V +
Sbjct 470 VY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGCKAIVKETNLICKALYLDYVQ-HKC 524
Query 465 GDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNI- 523
G+ E + + S L+ +K ++E+ F + + K + +
Sbjct 525 GNLHQRELLGV---------SDVWHKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVC 575
Query 524 --GEQKSILSPLY-----------AFASEAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
G +L L AF A ++ ++ S++ E S+ L AAI L
Sbjct 576 ADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKICHAVVSKSKELLDVSLDSLS-AAIHYL 634
Query 571 DGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDW 630
+ +++D SD T+ +V + T+ L VL
Sbjct 635 NS------KIVDLAQHFSDFGTS-------FVSKIVHFFKTFTTSTALAFAWVLFHVLHG 681
Query 631 LEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCA 690
+ + F+++ I ++ S V + AK + +S++ F +
Sbjct 682 AYIVVESDIYFVKN---IPRYASA-----VAQAFRSVAKVVLDSLRVTFIDGLSCFKIGR 733
Query 691 DSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMP---LKAPKEIIFLEGETL 747
I + G+K+ + G + HS L + L MP KA ++ I+L+G
Sbjct 734 RRICLSGSKIYEVERG---LLHSSQL------PLDVYDLTMPSQVQKAKQKPIYLKGSGS 784
Query 748 PTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMM 807
+ V + T L P E P V +CI + + + Y + +
Sbjct 785 DFSLADSVVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDGHV 839
Query 808 VTNNTFTLKGGAPTKVTFGDDT-VIEVQGY-KSVNITFELDERIDKVLNEKCSAYTVELG 865
+ A +VTF + V E+ K++ + +ELD+ + +LN C + V+
Sbjct 840 GLLDQAWRVPCAGRRVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGVFEVDDT 899
Query 866 TEVNEFACVVADAVIKTLQPVSEL---LTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
++ EF VV DA+ + L P EL + L + + +LFDE+GE LAS +YC
Sbjct 900 VDMEEFYAVVVDAIEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGEEVLASKLYC 959
Query 923 SFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQE--EDWL 980
+F P++D D EE E D G A + EE E ED L
Sbjct 960 AFTAPEDD----DFLEESGVEEDDVEGEETD---LTVTSAGEPCVASEQEESSEILEDTL 1012
Query 981 DDDSQQTVGQQDGSEDNQTT 1000
DD ED + +
Sbjct 1013 DDGPCVETSDSQVEEDVEMS 1032
Score = 194 bits (492), Expect = 3e-47, Method: Composition-based stats.
Identities = 59/251 (24%), Positives = 110/251 (44%), Gaps = 17/251 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D +
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + T V L ++ +D + ++ K++ ++++
Sbjct 1392 AGIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFDLISKCQITAVEGTKKLAERLSFNVGR 1451
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+ +K + L++ L ++ L ++ N ++
Sbjct 1452 SIVYETDANKLILSNDVA--------FVSTFNVLQDVLSLRHDIALDDDARTFVQSNVDV 1503
Query 1264 HPDSATLVSDI 1274
P+ +V+
Sbjct 1504 VPEGWRVVNKF 1514
Score = 48.9 bits (115), Expect = 0.002, Method: Composition-based stats.
Identities = 41/196 (21%), Positives = 73/196 (37%), Gaps = 22/196 (11%)
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
++ +V L K NNC+L + L +Q++ +F LQD + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1717 Y--CNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
N V + G V + + L + V C C LKG++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1775 SYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCG 1834
V C CG+ L+ + PF A + LK F Y+
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPFT------AHFALKDKLFCAFITKRSVYKAA 1216
Query 1835 HYKHITSKETLYCIDG 1850
+ ++ +DG
Sbjct 1217 CVVDVNDSHSMAVVDG 1232
>sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=1a PE=3 SV=1
Length=4383
Score = 3506 bits (9092), Expect = 0.0, Method: Composition-based stats.
Identities = 1058/2917 (36%), Positives = 1613/2917 (55%), Gaps = 115/2917 (4%)
Query 1531 GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSM 1588
G + + G T +K L + + + TVD +N + V +
Sbjct 1530 GGIDICSQDKVFGYVQQGSFNKATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGE 1585
Query 1589 TYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMS 1648
++G+ G + DG +VTK K +++GK F+ N + ++A D L Y +
Sbjct 1586 SFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYN 1645
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAA 1708
L + KW+ + K A+NNC++ + L LQ + LKF Q+A+ R+G A
Sbjct 1646 MLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPA 1705
Query 1709 NFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAV 1768
F +L+LA G+ D R+ + +F +L + CK CG +Q GV+AV
Sbjct 1706 RFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAV 1764
Query 1769 MYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYT 1828
M+ GTLS E + G + C+CGK+ + V+ + PF++ S PA +L G + A+ +
Sbjct 1765 MHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLICSNTPASVKLPKGVGS-ANIFK 1822
Query 1829 GNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGV 1887
G+ + GHY H+ +++ D + + K ++ G ++D Y +N T TY LD V
Sbjct 1823 GD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDV 1881
Query 1888 VCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNASFDNFKFVCDNIKFADDLNQLTG 1946
E P L YY Y+T++ I + + NFK + + D LN G
Sbjct 1882 KKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGVYTNFKLIGHTV--CDILNAKLG 1939
Query 1947 YKKPA-SRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY 2003
+ E KVT +P GDVV Y +++G KP++W H + N TY
Sbjct 1940 FDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLTY 1999
Query 2004 KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLE 2063
++ + N FDVLK +D +++ D K E I L
Sbjct 2000 ----------FNRPLLVDENKFDVLKVDDVDDGGDISESDAK-------EPKEINIIKLS 2042
Query 2064 CNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTL- 2122
K +V +I+ + +K + + D+ ++ ++ N LSR + + T+
Sbjct 2043 GVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLTGCRCVVRTANALSRAVNVPTIR 2102
Query 2123 --ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLC 2180
G+ V S+P D + + VV N ++ C N++ + F LL
Sbjct 2103 KFIKFGMTLV-SIPIDLLNLREIKPVFNVVKAVRNKIS-----ACFNFIKWLFVLLFGWI 2156
Query 2181 TFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINII--IWFLLLSV 2238
+ K T +A + + +F K ++ II I+ L +
Sbjct 2157 KISA----DNKVIYTTEVASKLTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNF 2212
Query 2239 CLGSLIY--------------STAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTG 2284
++I+ + + + + + C Y + YC G
Sbjct 2213 IYANVIFSDFYLPKIGFLPTFVGKIVQWIKNTFSLVTICDLYSIQDVGF----KNQYCNG 2268
Query 2285 SIPCSVCLSGLDSLDTYPSLETIQITISS--FKWDLTAFGLVAEWFLAYILFTRFFYVLG 2342
SI C CL+G D LD Y +++ +Q F +V E ++Y L+T +FY L
Sbjct 2269 SIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF 2328
Query 2343 LAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
+Q+ ++ + ++ W + L+++L M P +R YI ASF ++ + HV
Sbjct 2329 ALISIQILTTWLPELLMLSTLHWSVRLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHV 2388
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GC+ S C+ CYKRNR+ RV+C+TIV G+ R + V ANGG GFC H WNC++CD++
Sbjct 2389 AYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKP 2448
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G+TFI+ E A DLS + KRPI PTD + + V V + L++D+ GQ+TY+ + S
Sbjct 2449 GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFYDRDGQRTYDDVNASL 2508
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FV+ NL + K ++V+V + + ++++ +A+V+Y+Q + +PIL++D+ L++
Sbjct 2509 FVDYSNLLHSKVKSVPNMHVVVVENDA--DKANFLNAAVFYAQSLFRPILMVDKILITTA 2566
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
V MFD YV+TF S F+V + L L+ATA + + + + VL TF+S AR+
Sbjct 2567 NTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQICKVLDTFLSCARKS 2626
Query 2641 F-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHI 2699
+DSDV+TK + + + + + +E+T +SCNN + TY K +N+ DLG I SA+H+
Sbjct 2627 CSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHV 2686
Query 2700 NAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIA 2759
VAK ++ IW+V F LS + +++ A K L +LT V+V+TT +
Sbjct 2687 QGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLELTYNKQMANVSVLTTPFS 2746
Query 2760 LKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRD 2819
LKGG + + ++ ++LV + + P + + K YK +D GV RD
Sbjct 2747 LKGGAVFSYFVYVCFVLSLVCFI---GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRD 2803
Query 2820 IASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILRTT 2877
++ D CFANK FD W+ G Y+N ACP++ AV+ ++ G V +P +LR
Sbjct 2804 VSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACPIVVAVVDQDFGSTVFNVPTKVLRY- 2862
Query 2878 NGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTN 2937
LHF+ SA G CYTP I Y++F S CVL++ CT+F A G P PYCY
Sbjct 2863 GYHVLHFITHALSADGVQCYTPHSQISYSNFYASGCVLSSACTMFAMADGSPQPYCYTDG 2922
Query 2938 VLEGSVAYESLRPDTRYVLMDG-SIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGV 2996
+++ + Y SL P RY L + I+ P EG VR+V T YCR G CE ++ G+
Sbjct 2923 LMQNASLYSSLVPHVRYNLANAKGFIRLPEVLREGLVRIVRTRSMSYCRVGLCEEADEGI 2982
Query 2997 CVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIV 3056
C + +G WVLNNDYYRSLPG FCG D +L+ +F L QP+ L ++AS +AG I+A++
Sbjct 2983 CFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVI 3042
Query 3057 VTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYL 3116
V YY ++ +RAFG+Y+ +V N +++ ++F +L + VY L VY++ Y Y T Y
Sbjct 3043 VVLGFYYLIKLKRAFGDYTSIVFVNVIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYF 3102
Query 3117 TNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE 3176
+++S + H+QW+VM+ ++P W + YI + + H +W FS R++ + S TFE
Sbjct 3103 PSEISVIMHLQWLVMYGTIMPLWFCLLYISVVVSNHAFWVFS--YCRQLGTSVRSDGTFE 3160
Query 3177 EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAK 3236
E AL TF++ K+ Y KL++ L +NRYL+LYNKY+Y+SG MDT +YREAAC LAK
Sbjct 3161 EMALTTFMITKDSYCKLKNS--LSDVAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAK 3218
Query 3237 ALNDF-SNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
A++ F +N+GSDVLYQPP S++++ LQSG KM P+ KVE C+V VT G TLNGLWL
Sbjct 3219 AMDTFTNNNGSDVLYQPPTASVSTSFLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWL 3278
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVD 3355
DD VYCPRHVIC++ DM NP+Y +LL R ++ +F V + L V+ + MQ C+L L V
Sbjct 3279 DDKVYCPRHVICSASDMTNPDYTNLLCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVT 3338
Query 3356 TANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNI 3415
N +TPKY F ++PG+TF+VLA YNG P G + MR ++TIKGSFL GSCGSVG+ I
Sbjct 3339 LQNSRTPKYTFGVVKPGETFTVLAAYNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVI 3398
Query 3416 DYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAV 3475
DCV F YMH +EL TG H GTD G+FYGP+ D Q Q D +VN +AWLYAA+
Sbjct 3399 MGDCVKFVYMHQLELSTGCHTGTDFNGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAI 3458
Query 3476 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL 3535
+N WF+ ++ DFN+ A+ + + D V + L++ TG+++ + A++K L
Sbjct 3459 LNNCNWFVQSDKCSVEDFNVWALSNGFSQVKSDLV--IDALASMTGVSLETLLAAIKRL- 3515
Query 3536 QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLV 3595
+NG GR I+GS EDE TP DV +Q +G+ QS R +KG W++ + ++
Sbjct 3516 KNGFQGRQIMGSCSFEDELTPSDVYQQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIIT 3575
Query 3596 QSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN-MVY 3654
+W++F ++ N L + + + AM+ VKHKH +L ++++P L T+ Y N +V
Sbjct 3576 AFVKWTMFMYVTTN-MLSITFCALCVISLAMLLVKHKHLYLTMYIIPVLFTLLYNNYLVV 3634
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL-LILMTARTVYDDGARRVWTLMN 3713
++ + WL S+ + D V+Y +++ ++ +T R++ D + +
Sbjct 3635 YKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGMLLLIGMVFVTLRSINHDLFSFIMFVGR 3693
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+++V Y G+ L++ I + ++ S+ Y+ M A+ ++ V ++F
Sbjct 3694 VISVVSLWYMGSNLEEEILL--MLASLFGTYTWTTALSMAAAK-VIAKWVAVNVLYFTDI 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
++ +++ Y F+GY +CY+GLF L+N FR+ LGVY+Y +S QE RYMN+ GL PPKN
Sbjct 3751 PQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKN 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
S +A LN KLLG+GG P I+V+ QSK++DVKC + LL+ LQ L V S+SKLW C
Sbjct 3811 SFEALMLNFKLLGIGGVPIIEVSQFQSKLTDVKCANGGLLNCLQHLHVASNSKLWQYCST 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQAIASE 3947
LHN+IL D AFEK+ LL VL + AVD I ++C++ + LQA+ SE
Sbjct 3871 LHNEILATSDLGVAFEKLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSE 3930
Query 3948 FSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMAD 4006
F ++ S+ + A++ ++A ++G + + LK+L+K+ N+AKS ++RD A+ RKLE+MAD
Sbjct 3931 FVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAYERDRAVARKLERMAD 3990
Query 4007 QAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTT 4066
A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 3991 LALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLA 4050
Query 4067 AAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPL 4126
A L +++PD + Y D TYA +W+IQ + D+D QL EIS D + WPL
Sbjct 4051 ANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLHEISDDCN----WPL 4106
Query 4127 IVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLAL 4184
++ A R N SA LQNNEL P L+ +G QT T YYN + G+ V A+
Sbjct 4107 VIIANRHNEVSATVLQNNELMPAKLKTQVVNSGPDQTCNTPTQ--CYYNNSYNGKIVYAI 4164
Query 4185 LSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLG 4244
LSD+ LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V+G
Sbjct 4165 LSDVDGLKYTKILKDDGN-FVVLELDPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVG 4223
Query 4245 SLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGT 4304
++++TVRLQAG ATE +NS++LS CAF+VD K Y D++ GG PI NCVKMLC H GT
Sbjct 4224 TISSTVRLQAGTATEYASNSSILSLCAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGT 4283
Query 4305 GQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFT 4364
G AITV P+A Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV +
Sbjct 4284 GMAITVKPDATTSQDSYGGASVCIYCRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYV 4342
Query 4365 LKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
L + VC VCG W+ CSC + +QS D +FLN
Sbjct 4343 LTHDVCQVCGFWRDGSCSCVST-DTTVQSKDT-NFLN 4377
Score = 647 bits (1670), Expect = 0.0, Method: Composition-based stats.
Identities = 227/1040 (22%), Positives = 374/1040 (36%), Gaps = 183/1040 (18%)
Query 43 RQHLKDGTCGLVEVE----------KGVLPQLEQPYVFIKRSDA---RTAPHGHVMVEL- 88
+ L+ LV +G P +F +RS R A + HV +L
Sbjct 94 QDALQSREAVLVTPPLGMSLEACYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAYQLY 153
Query 89 VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKNGNKGA-------GGHS 135
+ + G+ +G +G+ +G ++P + +PV RK + LRK G KGA GG
Sbjct 154 MIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIAPWVMYLRKCGEKGAYIKDYKRGGFE 211
Query 136 YGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
+ + K D D + +P F + L+R G YVD C G
Sbjct 212 HVYNFKVEDAYDLVHDEPKGKFSKK---------AYALIRGYRGVKPLLYVDQYGCDYTG 262
Query 196 ---YPLECIKDLLARAGKASCTL-SEQLDFIDTKRGVYCCREHEHEIAWYTERSEK-SYE 250
LE D + KA + S++L F + +AW+ R +
Sbjct 263 GLADGLEAYADKTLQEMKALFPIWSQELPF-------------DVTVAWHVVRDPRYVMR 309
Query 251 LQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFM---- 297
LQ+ I+ D +G P V+ +SII + + L M
Sbjct 310 LQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYADDSII------LRQHNLVDIMSCFY 363
Query 298 ----GRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCEF-CGTENLT 350
+ + Y V +C + + C D C W G+ + CG T
Sbjct 364 MEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCDFKGWVPGNMIDGFACTTCGHVYET 422
Query 351 KEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGC 409
+ A + G LP N V+ A + G + S Y G + FGGC
Sbjct 423 GDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFTLY------------GQTVVYFGGC 469
Query 410 VFSYVGCHNKCAYWVPRASANI----GCNHTGVVGEGSEGLNDNL-LEILQKEKVNINIV 464
V+ + N W+P +++ G +TGVVG + NL + L + V +
Sbjct 470 VY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGCKAIVKETNLICKALYLDYVQ-HKC 524
Query 465 GDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNI- 523
G+ E + + S L+ +K ++E+ F + + K + +
Sbjct 525 GNLHQRELLGV---------SDVWHKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVC 575
Query 524 --GEQKSILSPLY-----------AFASEAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
G +L L AF A ++ ++ S++ E SV L AAI L
Sbjct 576 ADGFMPFLLDDLVPRAYYLAVSGQAFCDYAGKICHAVVSKSKELLDVSVDSL-GAAIHYL 634
Query 571 DGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDW 630
+ +++D SD T+ +V + T+ L VL
Sbjct 635 NS------KIVDLAQHFSDFGTS-------FVSKIVHFFKTFTTSTALAFAWVLFHVLHG 681
Query 631 LEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCA 690
+ + F ++ I ++ S V + AK +S++ F +
Sbjct 682 AYIVVESDIYFGKN---IPRYASA-----VAQAFRSGAKVGLDSLRVTFIDGLSCFKIGR 733
Query 691 DSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMP---LKAPKEIIFLEGETL 747
I + G+K+ + G + HS L + L MP K ++ I+L+G
Sbjct 734 RRICLSGSKIYEVERG---LLHSSQL------PLDVYDLTMPSQVQKTKQKGIYLKGSGS 784
Query 748 PTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMM 807
+ V + T L P E P V +CI + + + Y + +
Sbjct 785 DFSLADSVVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDGHV 839
Query 808 VTNNTFTLKGGAPTKVTFGDDT-VIEVQGY-KSVNITFELDERIDKVLNEKCSAYTVELG 865
+ A VTF + V E+ K++ + +ELD+ + +LN C + V+
Sbjct 840 GLLDQAWRVPCAGRCVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGEFEVDDT 899
Query 866 TEVNEFACVVADAVIKTLQPVSEL---LTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
++ EF VV DA+ + L P EL + L + + +LFDE+GE LA +YC
Sbjct 900 VDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGEEVLAPKLYC 959
Query 923 SFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQE--EDWL 980
+F P++D D EE E D G A + EE E ED L
Sbjct 960 AFTAPEDD----DFLEESGVEEDDVEGEETD---LTVTSAGEPCVASEQEESSEILEDTL 1012
Query 981 DDDSQQTVGQQDGSEDNQTT 1000
DD ED Q +
Sbjct 1013 DDGPCVETSDSQVEEDVQMS 1032
Score = 194 bits (494), Expect = 2e-47, Method: Composition-based stats.
Identities = 59/251 (24%), Positives = 111/251 (44%), Gaps = 17/251 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D +
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + T + V L ++ +D + ++ K++ ++++
Sbjct 1392 AGIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLISKCQITAVEGTKKLAERLSFNVGR 1451
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+ +K + L++ L ++ L ++ N ++
Sbjct 1452 SIVYETDANKLILSNDVA--------FVSTFNVLQDVLSLRHDIALDDDARTFVQSNVDV 1503
Query 1264 HPDSATLVSDI 1274
P+ +V+
Sbjct 1504 VPEGWRVVNKF 1514
Score = 48.9 bits (115), Expect = 0.002, Method: Composition-based stats.
Identities = 41/196 (21%), Positives = 73/196 (37%), Gaps = 22/196 (11%)
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
++ +V L K NNC+L + L +Q++ +F LQD + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1717 Y--CNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
N V + G V + + L + V C C LKG++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1775 SYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCG 1834
V C CG+ L+ + PF A + LK F Y+
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPFT------AHFALKDKLFCAFITKRSVYKAA 1216
Query 1835 HYKHITSKETLYCIDG 1850
+ ++ +DG
Sbjct 1217 CVVDVNDSHSMAVVDG 1232
>sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=1a PE=3 SV=1
Length=4383
Score = 3503 bits (9083), Expect = 0.0, Method: Composition-based stats.
Identities = 1060/2917 (36%), Positives = 1614/2917 (55%), Gaps = 115/2917 (4%)
Query 1531 GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSM 1588
G + + G T +K L + + + TVD +N + V +
Sbjct 1530 GGIDICSQDKVFGYVQQGSFNKATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGE 1585
Query 1589 TYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMS 1648
++G+ G + DG +VTK K +++GK F+ N + ++A D L Y +
Sbjct 1586 SFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYN 1645
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAA 1708
L + KW+ + K A+NNC++ + L LQ + LKF Q+A+ R+G A
Sbjct 1646 MLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPA 1705
Query 1709 NFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAV 1768
F +L+LA G+ D R+ + +F +L + CK CG +Q GV+AV
Sbjct 1706 RFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAV 1764
Query 1769 MYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYT 1828
M+ GTLS E + G + C+CGK+ + V+ + PF++ S PA +L G + A+ +
Sbjct 1765 MHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLICSNTPASVKLPKGVGS-ANIFK 1822
Query 1829 GNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGV 1887
G+ + GHY H+ +++ D + + K ++ G ++D Y +N T TY LD V
Sbjct 1823 GD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDV 1881
Query 1888 VCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNASFDNFKFVCDNIKFADDLNQLTG 1946
E P L YY Y+T++ I + + NFK + + D LN G
Sbjct 1882 KKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGVYTNFKLIGHTV--CDILNAKLG 1939
Query 1947 YKKPA-SRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY 2003
+ E KVT +P GDVV Y +++G KP++W H + N TY
Sbjct 1940 FDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLTY 1999
Query 2004 KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLE 2063
++ + N FDVLK +D +++ D K E I L
Sbjct 2000 ----------FNRPLLVDENKFDVLKVDDVDDGGDISESDAK-------EPKEINIIKLS 2042
Query 2064 CNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTL- 2122
K +V +I+ + +K + + D+ ++ ++ N LSR + + T+
Sbjct 2043 GVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLTGCRCVVRTANALSRAVNVPTIR 2102
Query 2123 --ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLC 2180
G+ V S+P D + + VV N ++ C N++ + F LL
Sbjct 2103 KFIKFGMTLV-SIPIDLLNLREIKPVFNVVKAVRNKIS-----ACFNFIKWLFVLLFGWI 2156
Query 2181 TFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINII--IWFLLLSV 2238
+ K T +A + + +F K ++ II I+ L +
Sbjct 2157 KISA----DNKVIYTTEVASKLTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNF 2212
Query 2239 CLGSLIYSTAALG--------------VLMSNLGMPSYCTGYREGYLNSTNVTIATYCTG 2284
++I+S L + + + + C Y + YC G
Sbjct 2213 IYANVIFSDFYLPKIGFLPTFVGKIAQWIKNTFSLVTICDLYSIQDVGF----KNQYCNG 2268
Query 2285 SIPCSVCLSGLDSLDTYPSLETIQITISS--FKWDLTAFGLVAEWFLAYILFTRFFYVLG 2342
SI C CL+G D LD Y +++ +Q F +V E ++Y L+T +FY L
Sbjct 2269 SIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF 2328
Query 2343 LAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
+Q+ ++ F+ ++ W + L+++L M P +R YI ASF ++ + HV
Sbjct 2329 ALISIQILTTWLPELFMLSTLHWSVRLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHV 2388
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GC+ S C+ CYKRNR+ RV+C+TIV G+ R + ANGG GFC H WNC++CD++
Sbjct 2389 AYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRYYDAMANGGTGFCSKHQWNCIDCDSYKP 2448
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G+TFI+ E A DLS + KRPI PTD + + V V + L++D+ GQ+TY+ + S
Sbjct 2449 GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFYDRDGQRTYDDVNASL 2508
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FV+ NL + K ++V+V + + ++++ +A+V+Y+Q + +PIL++D+ L++
Sbjct 2509 FVDYSNLLHSKVKSVPNMHVVVVENDA--DKANFLNAAVFYAQSLFRPILMVDKNLITTA 2566
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
V MFD YV+TF S F+V + L L+ATA + + + + VL TF+S AR+
Sbjct 2567 NTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQICKVLDTFLSCARKS 2626
Query 2641 F-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHI 2699
+DSDV+TK + + + + + +E+T +SCNN + TY K +N+ DLG I SA+H+
Sbjct 2627 CSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHV 2686
Query 2700 NAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIA 2759
VAK ++ IW+V F LS + +++ A K L KLT V+V+TT +
Sbjct 2687 QGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFS 2746
Query 2760 LKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRD 2819
LKGG + + ++ ++LV + + P + + K YK +D GV RD
Sbjct 2747 LKGGAVFSYFVYVCFVLSLVCFI---GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRD 2803
Query 2820 IASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILRTT 2877
++ D CFANK FD W+ G Y+N ACP++ AV+ ++ G V +P +LR
Sbjct 2804 VSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACPIVVAVVDQDFGSTVFNVPTKVLRY- 2862
Query 2878 NGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTN 2937
LHF+ SA G CYTP I Y++F S CVL++ CT+F A G P PYCY
Sbjct 2863 GYHVLHFITHALSADGVQCYTPHSQISYSNFYASGCVLSSACTMFAMADGSPQPYCYTDG 2922
Query 2938 VLEGSVAYESLRPDTRYVLMDG-SIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGV 2996
+++ + Y SL P RY L + I+FP EG VR+V T YCR G CE ++ G+
Sbjct 2923 LMQNASLYSSLVPHVRYNLANAKGFIRFPEVLREGLVRIVRTRSMPYCRVGLCEEADEGI 2982
Query 2997 CVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIV 3056
C + +G WVLNNDYYRSLPG FCG D +L+ +F L QP+ L ++AS +AG I+A++
Sbjct 2983 CFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVI 3042
Query 3057 VTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYL 3116
V + YY ++ +RAFG+Y+ +V N +++ ++F +L + VY L VY++ Y Y T Y
Sbjct 3043 VVLVFYYLIKLKRAFGDYTSIVFVNVIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYF 3102
Query 3117 TNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE 3176
+++S + H+QW+VM+ ++P W + YI + + H +W FS R++ + S TFE
Sbjct 3103 PSEISVIMHLQWLVMYGTIMPLWFCLLYISVVVSNHAFWVFS--YCRQLGTSVRSDGTFE 3160
Query 3177 EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAK 3236
E AL TF++ K+ Y KL++ L +NRYL+LYNKY+Y+SG MDT +YREAAC LAK
Sbjct 3161 EMALTTFMITKDSYCKLKNS--LSDVAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAK 3218
Query 3237 ALNDF-SNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
A++ F +N+GSDVLYQPP S++++ LQSG KM P+ KVE C+V VT G TLNGLWL
Sbjct 3219 AMDTFTNNNGSDVLYQPPTASVSTSFLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWL 3278
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVD 3355
D VYCPRHVIC++ DM NP+Y +LL R ++ +F V + L V+ + MQ C+L L V
Sbjct 3279 GDKVYCPRHVICSASDMTNPDYTNLLCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVT 3338
Query 3356 TANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNI 3415
N +TPKY F ++PG+TF+VLA YNG P G + MR ++TIKGSFL GSCGSV + I
Sbjct 3339 LQNSRTPKYTFGVVKPGETFTVLAAYNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVVYVI 3398
Query 3416 DYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAV 3475
DCV F YMH +EL TG H GTD G+FYGP+ D Q Q D +VN +AWLYAA+
Sbjct 3399 MGDCVKFVYMHQLELSTGCHTGTDFNGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAI 3458
Query 3476 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL 3535
+N WF+ ++ DFN+ A+ + + D V + L++ TG+++ + A++K L
Sbjct 3459 LNNCNWFVQSDKCSVEDFNVWALSNGFSQVKSDLV--IDALASMTGVSLETLLAAIKHL- 3515
Query 3536 QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLV 3595
+NG GR I+GS EDE TP DV +Q +G+ QS R +KG W++ + ++
Sbjct 3516 KNGFQGRQIMGSCSFEDELTPSDVYQQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIIT 3575
Query 3596 QSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN-MVY 3654
+W++F ++ N L + + + M+ VKHKH +L ++++P L T+ Y N +V
Sbjct 3576 AFVKWTMFMYVTTN-MLSITFCALCVISLTMLLVKHKHLYLTMYIIPVLFTLLYNNYLVV 3634
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL-LILMTARTVYDDGARRVWTLMN 3713
++ + WL S+ + D V+Y +++ ++ +T R++ + +
Sbjct 3635 YKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGMLLLIGMVFVTLRSINQYLFSFIMFVGR 3693
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
V+++V Y G+ L++ I + ++ S+ Y+ M A+ ++ V ++F
Sbjct 3694 VISVVSLWYMGSNLEEEILL--MLASLFGTYTWTTALSMAAAK-VIAKWVAVNVLYFTDI 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
++ +++ Y F+GY +CY+GLF L+N FR+ LGVY+Y +S QE RYMN+ GL PPKN
Sbjct 3751 PQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKN 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
S +A LN KLLG+GG P I+V+ QSK++DVKC +VVLL+ LQ L V S+SKLW C
Sbjct 3811 SFEALMLNFKLLGIGGVPIIEVSQFQSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCST 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQAIASE 3947
LHN+IL D AFEK+ LL VL + AVD I ++C++ + LQA+ SE
Sbjct 3871 LHNEILATSDLGVAFEKLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSE 3930
Query 3948 FSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMAD 4006
F ++ S+ + A++ ++A ++G + + LK+L+K+ N+AKS ++RD A+ RKLE+MAD
Sbjct 3931 FVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAYERDRAVARKLERMAD 3990
Query 4007 QAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTT 4066
A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 3991 LALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLA 4050
Query 4067 AAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPL 4126
A L +++PD + Y D TYA +W+IQ + D+D QL EIS D + WPL
Sbjct 4051 ANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQLHEISDDCN----WPL 4106
Query 4127 IVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLAL 4184
++ A R N SA LQNNEL P L+ +G QT T YYN + G+ V A+
Sbjct 4107 VIIANRHNEVSATALQNNELMPAKLKTQVVNSGPDQTCNTPTQ--CYYNNSYNGKIVYAI 4164
Query 4185 LSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLG 4244
LSD+ LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V+G
Sbjct 4165 LSDVDGLKYTKILKDDGN-FVVLELDPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVG 4223
Query 4245 SLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGT 4304
++++TVRLQAG ATE +NS++LS CAF+VD K Y D++ GG PI NCVKMLC H GT
Sbjct 4224 TISSTVRLQAGTATEYASNSSILSLCAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGT 4283
Query 4305 GQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFT 4364
G AITV P+A Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV +
Sbjct 4284 GMAITVKPDATTSQDSYGGASVCIYCRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYV 4342
Query 4365 LKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
L + VC VCG W+ CSC + +QS D +FLN
Sbjct 4343 LTHDVCQVCGFWRDGSCSCVST-DTTVQSKDT-NFLN 4377
Score = 654 bits (1687), Expect = 0.0, Method: Composition-based stats.
Identities = 226/1040 (22%), Positives = 376/1040 (36%), Gaps = 183/1040 (18%)
Query 43 RQHLKDGTCGLVEVE----------KGVLPQLEQPYVFIKRSDA---RTAPHGHVMVEL- 88
+ L+ LV +G P +F +RS R A + HV +L
Sbjct 94 QDALQSREAVLVTPPLGMSLEACYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAYQLY 153
Query 89 VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKNGNKGA-------GGHS 135
+ + G+ +G +G+ +G ++P + +PV RK + LRK G KGA GG
Sbjct 154 MIDPAGVCFG-AGQFVGWVIP-LAFMPVQSRKFIVPWVMYLRKCGEKGAYNKDHKRGGFE 211
Query 136 YGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
+ + K D D + +P F + L+R G YVD C G
Sbjct 212 HVYNFKVEDAYDLVHDEPKGKFSKK---------AYALIRGYRGVKPLLYVDQYGCDYTG 262
Query 196 ---YPLECIKDLLARAGKASCTL-SEQLDFIDTKRGVYCCREHEHEIAWYTERSEK-SYE 250
LE D + KA + S++L F + +AW+ R +
Sbjct 263 GLADGLEAYADKTLQEMKALFPIWSQELPF-------------DVTVAWHVVRDPRYVMR 309
Query 251 LQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFM---- 297
LQ+ I+ D +G P V+ +SII + + L M
Sbjct 310 LQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYADDSII------LRQHNLVDIMSCFY 363
Query 298 ----GRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCEF-CGTENLT 350
+ + Y V +C + + C D C W G+ + CG T
Sbjct 364 MEADAVVNAFYGV-DLKDCGFVMQFGYIDCEQDLCDFKGWVPGNMIDGFACTTCGHVYET 422
Query 351 KEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGC 409
+ A + G LP N V+ A + G + S Y G + FGGC
Sbjct 423 GDLLAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFTLY------------GQTVVYFGGC 469
Query 410 VFSYVGCHNKCAYWVPRASANI----GCNHTGVVGEGSEGLNDNL-LEILQKEKVNINIV 464
V+ + N W+P +++ G +TGVVG + NL + L + V +
Sbjct 470 VY-WSPARN---IWIPILKSSVKSYDGLVYTGVVGCKAIVKETNLICKALYLDYVQ-HKC 524
Query 465 GDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNI- 523
G+ E + + S L+ +K ++E+ F + + K + +
Sbjct 525 GNLHQRELLGV---------SDVWHKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVC 575
Query 524 --GEQKSILSPLY-----------AFASEAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
G +L L AF A ++ ++ S++ E S+ L AAI L
Sbjct 576 ADGFMPFLLDDLVPRAYYLAVSGQAFCDYAGKICHAVVSKSKELLDVSLDSL-GAAIHYL 634
Query 571 DGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDW 630
+ +++D SD T+ +V + T+ L VL
Sbjct 635 NS------KIVDLAQHFSDFGTS-------FVSKIVHFFKTFTTSTALAFAWVLFHVLHG 681
Query 631 LEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCA 690
+ + F+++ I ++ S V + AK + +S++ F +
Sbjct 682 AYIVVESDIYFVKN---IPRYASA-----VAQAFRSVAKVVLDSLRVTFIDGLSCFKIGR 733
Query 691 DSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMP---LKAPKEIIFLEGETL 747
I + G+K+ + G + HS L + L MP K ++ I+L+G
Sbjct 734 RRICLSGSKIYEVERG---LLHSSQL------PLDVYDLTMPSQVQKTKQKPIYLKGSGS 784
Query 748 PTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMM 807
+ V + T L P E P V +CI + + + Y + +
Sbjct 785 DFSLADSVVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDGHV 839
Query 808 VTNNTFTLKGGAPTKVTFGDDT-VIEVQGY-KSVNITFELDERIDKVLNEKCSAYTVELG 865
+ A VTF + V E+ K++ + +ELD+ + +LN C + V+
Sbjct 840 GLLDQAWRVPCAGRCVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGVFEVDDT 899
Query 866 TEVNEFACVVADAVIKTLQPVSEL---LTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
++ EF VV DA+ + L P EL + L + + +LFDE+GE LA +YC
Sbjct 900 VDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGEEVLAPKLYC 959
Query 923 SFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQE--EDWL 980
+F P++D D EE E D G A + EE E ED L
Sbjct 960 AFTAPEDD----DFLEESGVEEDDVEGEETD---LTVTSAGEPCVASEQEESSEILEDTL 1012
Query 981 DDDSQQTVGQQDGSEDNQTT 1000
DD ED Q +
Sbjct 1013 DDGPCVETSDSQVEEDVQMS 1032
Score = 194 bits (494), Expect = 2e-47, Method: Composition-based stats.
Identities = 59/251 (24%), Positives = 111/251 (44%), Gaps = 17/251 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV DI++ +K+VK VVVN AN ++ HGGGVA A+ A E+ D +
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ G G V +G L K L+VVGP+ + LL+ Y++ N+++ ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + T + V L ++ +D + ++ K++ ++++
Sbjct 1392 AGIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLISKCQITAVEGTKKLAERLSFNVGR 1451
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+ +K + L++ L ++ L ++ N ++
Sbjct 1452 SIVYETDANKLILSNDVA--------FVSTFNVLQDVLSLRHDIALDDDARTFVQSNVDV 1503
Query 1264 HPDSATLVSDI 1274
P+ +V+
Sbjct 1504 VPEGWRVVNKF 1514
Score = 48.9 bits (115), Expect = 0.003, Method: Composition-based stats.
Identities = 41/196 (21%), Positives = 73/196 (37%), Gaps = 22/196 (11%)
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
++ +V L K NNC+L + L +Q++ +F LQD + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1717 Y--CNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
N V + G V + + L + V C C LKG++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1775 SYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCG 1834
V C CG+ L+ + PF A + LK F Y+
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPFT------AHFALKDKLFCAFITKRSVYKAA 1216
Query 1835 HYKHITSKETLYCIDG 1850
+ ++ +DG
Sbjct 1217 CVVDVNDSHSMAVVDG 1232
>sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=1a PE=3 SV=1
Length=4421
Score = 3493 bits (9058), Expect = 0.0, Method: Composition-based stats.
Identities = 1066/2942 (36%), Positives = 1601/2942 (54%), Gaps = 121/2942 (4%)
Query 1512 KDWSYSGQ-STQLGIEFLKR----GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLRE 1564
KDW + G++ +K + + DG T + + LL+
Sbjct 1543 KDWRLINKFDVINGVKTVKYFECPNSIYICSQGKDFGYVCDGSFYKATVNQVCVLLA--- 1599
Query 1565 VRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPND 1624
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1600 -KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENL 1658
Query 1625 DTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQ 1684
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1659 SLADISAVQSSFGFDQQQLLAYYNFL-TVCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQ 1717
Query 1685 QIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSC 1744
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1718 HINLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGA 1777
Query 1745 KRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF
Sbjct 1778 ICELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPF 1835
Query 1805 VMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPIT 1864
++ S P +L A+ + G GHY H+ D + K + G +T
Sbjct 1836 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1893
Query 1865 DVFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP-- 1921
D Y +N + T T Y LD V +P L YY + Y+T +PI +P+
Sbjct 1894 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKV 1952
Query 1922 NASFDNFKFVCDNIKFADDLNQLTGYKKP-ASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
+ + NFK V +I LN G+ E KVT +P GDVV Y +
Sbjct 1953 DGVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYF 2010
Query 1981 KGAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDN 2038
KG + KP++W H + N TY ++ ++ N + VL D+
Sbjct 2011 KGCETFGKPVIWFCHDEASLNSLTY----------FNKPSFKSENRYSVLSV------DS 2054
Query 2039 LACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMA 2097
++ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2055 VSEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWD 2114
Query 2098 AYVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT 2154
Y+ + NELSR++ T+ +G+ + ++P D + N+ +
Sbjct 2115 MYLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRDD---NQTLLVPK 2170
Query 2155 NIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEAS 2214
R + ++ + F + L FT T IA ++ L+ +
Sbjct 2171 IFKARAIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNA 2224
Query 2215 FNYLKSPNFSKLIN-----IIIWF--LLLSVCLGSL---------IYSTAALGVLMSNLG 2258
F + F K + WF L ++V I+ + + + G
Sbjct 2225 FQTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFG 2284
Query 2259 MPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKW-- 2316
+ + C Y + + T+ +C GS C +C SG D LDTY +++ +Q +
Sbjct 2285 LVTICDFYSKLGVGFTS----HFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFD 2340
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2341 YVSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2400
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2401 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2460
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2461 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2520
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + + + ++
Sbjct 2521 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVESDA--DRANF 2578
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2579 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQIMFDVYVDTFMSHFDVDRKSFNNFVN 2638
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2639 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2698
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK NI+ IW + F L+ L+ +++ A
Sbjct 2699 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKVANISCIWFIDAFNQLTADLQHKLKKAC 2758
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L ++L+ + + + P
Sbjct 2759 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPT 2815
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ G Y N C
Sbjct 2816 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDC 2875
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2876 PIVVAVMDEDIGSTMFNVPTKVLRY-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2934
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2935 GCVLSSLCTMFKRGDGTPHPYCYTDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 2994
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 2995 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDFFDLFYQF 3054
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3055 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFL 3114
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3115 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3174
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N S STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3175 NHVLWLFS--YCRKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3230
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3231 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3290
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R + +F
Sbjct 3291 VSPTSKIEPCLVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDF 3350
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3351 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAF 3410
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3411 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFNGNFYGPYR 3470
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM + + D
Sbjct 3471 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADL 3530
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3531 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3587
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + + ++ +F M+ V
Sbjct 3588 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYINTH-MIGVTLCVLCFVSFMMLLV 3646
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3647 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYEVFYGCIL 3706
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3707 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTWTT 3764
Query 3749 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 3808
+ +A+ IV + +F ++ I+L Y F+GY +CY+G F LLN FR+ +
Sbjct 3765 ILSLAIAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPM 3823
Query 3809 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCT 3868
GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3824 GVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCA 3883
Query 3869 SVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD-- 3926
+VVLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL S AVD
Sbjct 3884 NVVLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFSNPAAVDTK 3943
Query 3927 ----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLK 3981
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L+
Sbjct 3944 CLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLE 4003
Query 3982 KSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLD 4041
K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLD
Sbjct 4004 KACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 4063
Query 4042 NDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQV 4101
N ALN+I++NA GCVPL+ IP A L ++IPD + D TYA ++W IQ V
Sbjct 4064 NQALNSILDNAVKGCVPLSAIPALAANTLTIIIPDKQVFDKVVDNVYVTYAGSVWHIQTV 4123
Query 4102 VDADSKIVQLSEISMDNSPNLAWPLIVTALRANS--AVKLQNNELSPVALRQMSCAAGTT 4159
DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4124 QDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSD 4179
Query 4160 QTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDT 4219
YYN GR V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4180 INCNIPTQ--CYYNNVSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFSIQD 4236
Query 4220 PKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKA 4279
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VD K
Sbjct 4237 VKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKT 4296
Query 4280 YKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNP 4339
Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+
Sbjct 4297 YLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDV 4356
Query 4340 KGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSF 4399
G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D +F
Sbjct 4357 DGICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SSVAVQSKDL-NF 4413
Query 4400 LN 4401
LN
Sbjct 4414 LN 4415
Score = 432 bits (1112), Expect = 3e-119, Method: Composition-based stats.
Identities = 203/1117 (18%), Positives = 379/1117 (34%), Gaps = 202/1117 (18%)
Query 13 HVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGVLPQLEQPYVFIK 72
HVQ +L +RD+ V + + V + +K GT L++ L + YV
Sbjct 71 HVQSNL----IRDIFVH---EDLHVVEVLTKTAVKSGTAILIKSPLHSLGGFPKGYVMGL 123
Query 73 RSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKN 126
+T +V+ L +G G +VP G +P K + ++
Sbjct 124 FRSYKTK--RYVVHHLSMTTSTTNFGED--FFGWIVPF-GFMPSYVHKWFQFCRLYIEES 178
Query 127 GNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYV 186
+ D E+ +P + + L+R+ G +V
Sbjct 179 DLIISNFKFDDYDFSVEAAYAEVHAEPKGKYSQK---------AYALLRQYRGIKPVLFV 229
Query 187 DNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSE 246
D C G +C++ +L + + + +AW+ R
Sbjct 230 DQYGCDYSGKLADCLQAY------GHYSLQDMRQKQSVW---LANCDFDIVVAWHVVRDS 280
Query 247 K-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGF 296
+ LQT I K D +G+ P + ++I+ + P + K
Sbjct 281 RFVMRLQTIATICGIKYVAQPTEDVVDGDVVIREPVHLLSADAIVLKL-PSLMKVMTHMD 339
Query 297 MGRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCE-FCGTENLTKE- 352
I+S+Y V +C + + C D+C W +G+ + C T + E
Sbjct 340 DFSIKSIYNV-DLCDCGFVMQYGYVDCFNDNCDFYGWVSGNMMDGFSCPLCCTVYDSSEV 398
Query 353 GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFS 412
A + G +P+N V+ + + G FG C++
Sbjct 399 KAQSSGVIPENPVL-----------------FTNSTDTVNPDSFNLYGYSVTPFGSCIY- 440
Query 413 YVGCHNKCAYWVPRASANIGC----NHTGVVGEGSEGLNDNLL-EILQKEKVNINIVGDF 467
+ W+P +++ ++GVVG S L+ L + V G+
Sbjct 441 WSPRPG---LWIPIIKSSVKSYDDLVYSGVVGCKSIVKETALITHALYLDYVQC-KCGNL 496
Query 468 KLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQK 527
+ N + G++ +Q++ + G++ +
Sbjct 497 EQNH-------------------ILGVNNSWCRQLLLNRGDYNM---------------- 521
Query 528 SILSPLYAFASEAARVVRSIFSRTLETAQNSVRV------------LQKAAITILDGISQ 575
+L + F R+ F+ + L ++ I +SQ
Sbjct 522 -LLKNIDLFVKR-----RADFACKFAVCGDGFVPFLLDGLIPRSYYLIQSGIFFTSLMSQ 575
Query 576 YSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW----------LTNIFGTVYEKL 624
+S + D + L + + V YI V +L +Q+ + N F T+ +
Sbjct 576 FSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDAS 635
Query 625 KPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNK 684
P WL + G F+ + A I AK + TFFKL+
Sbjct 636 APATGWLLYQLLNGF-----------FVVSQANLNFVALIPDYAKILVNKFYTFFKLL-- 682
Query 685 FLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSREETGLLMPLKA-PKE 738
L ++ LK +N +G F S GL G ++P A ++
Sbjct 683 -LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI---------PGFVLPCNAQEQQ 732
Query 739 IIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTPVCINGLMLLEIKDT 796
I F EG + E V+++ ++ ++ S E + P +CI M +
Sbjct 733 IYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGD 785
Query 797 EKYCALAPNMMV-TNNTFTLKGGAPTKVTFGDDTVI-EVQGYKSVNITFELDERIDKVLN 854
+ + + + + + A KV F + V+ E+ +V + F+LD D +L
Sbjct 786 KFFPIVMNDKNICLLDHAWRFPCAGRKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILG 845
Query 855 EKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDES 911
+ CS + VE G V++F VV DA+ L E + + L++ + YLFDE+
Sbjct 846 KVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQVRAFLNKLNENVVYLFDEA 905
Query 912 GEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTEDD------YQGKPLEFGA 964
G+ +AS MYC+F D ED + E+ + + ++D +
Sbjct 906 GDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDDEDVVTGDNDDEDVVTGDN 965
Query 965 TSAALQPEEEQEEDWL---DDDSQQTVGQQD------GSEDNQTTTIQTIVEVQPQLEME 1015
+ + +ED + +DD G D G D++ +
Sbjct 966 DDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDN 1025
Query 1016 LTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKV 1052
V T + N D+ + D V++ + +
Sbjct 1026 NDEDVVTGDNNDEESVTGDNDDQIVVTGDDVDDIESI 1062
Score = 197 bits (501), Expect = 3e-48, Method: Composition-based stats.
Identities = 64/254 (25%), Positives = 106/254 (42%), Gaps = 17/254 (7%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A E+ +
Sbjct 1308 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1367
Query 1092 ATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLL 1149
+ G +VG V +G L K L++VGP+ + LL AY++ N ++ L+ L+
Sbjct 1368 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1427
Query 1150 SAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPK 1208
SAGIF SL + V V L +K +D + + K + ++
Sbjct 1428 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDIIQKCQITSVVGTKALAVRLTANVG 1487
Query 1209 EEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDI------NGN 1262
+K K + C ++ ++E L ++ L D+
Sbjct 1488 RVIKFETDAYKLFLSGD--------DCFVSNSSVIQEVLLLRHDIQLNNDVRDYLLSKMT 1539
Query 1263 LHPDSATLVSDIDI 1276
P L++ D+
Sbjct 1540 SLPKDWRLINKFDV 1553
Score = 55.1 bits (131), Expect = 4e-05, Method: Composition-based stats.
Identities = 42/201 (21%), Positives = 73/201 (36%), Gaps = 21/201 (10%)
Query 1596 PTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKK 1655
D D + + + ++ Y L V D ++S + +
Sbjct 1040 SVTGDNDDQIVVTGDDVDDIESIYDFDTYKALLV-------FNDVYNDALFVSYGSSVET 1092
Query 1656 WKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALIL 1715
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1093 ETYFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLL 1152
Query 1716 AYCNKTVGEL--GDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGT 1773
K + G V + + ++ N C CG L G++AV + G
Sbjct 1153 TTIPKAIVLPQGGYVADFAYWFLNQFDI---NAYANWCCLKCGF-SFDLNGLDAVFFYGD 1208
Query 1774 LSYEQFKKGVQIPCTCGKQAT 1794
+ V C CG T
Sbjct 1209 I--------VSHVCKCGHNMT 1221
>sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus
OC43 OX=31631 GN=1a PE=1 SV=1
Length=4383
Score = 3492 bits (9055), Expect = 0.0, Method: Composition-based stats.
Identities = 1064/2917 (36%), Positives = 1610/2917 (55%), Gaps = 115/2917 (4%)
Query 1531 GDKSVYYTSNPTTFHLDG--EVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSM 1588
G + + G T +K L + + + TVD +N + V +
Sbjct 1530 GGIDICSQDKVFGYVQQGIFNKATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGE 1585
Query 1589 TYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMS 1648
++G+ G + DG +VTK K +++GK F+ N + ++A D L Y +
Sbjct 1586 SFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYN 1645
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAA 1708
L + KW+ + K A+NNC++ + L LQ + L F Q+A+ R+G A
Sbjct 1646 MLVNCFKWQVVVNGKYFTFKQANNNCFVNVSCLMLQSLHLTFKIVQWQEAWLEFRSGRPA 1705
Query 1709 NFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAV 1768
F AL+LA G+ D R+ + +F +L + CK CG +Q G++AV
Sbjct 1706 RFVALVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGLDAV 1764
Query 1769 MYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYT 1828
M+ GTLS E + G + C+CGK+ + V+ + PF++ S PA +L G + A+ +
Sbjct 1765 MHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLICSNTPASVKLPKGVGS-ANIFI 1822
Query 1829 GNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKEN-SYTTTIKPVTYKLDGV 1887
G+ GHY H+ +++ D + + K ++ G ++D Y +N T TY LD V
Sbjct 1823 GD-NVGHYVHVKCEQSYQLYDASNVKKVTDVTGKLSDCLYLKNLKQTFKSVLTTYYLDDV 1881
Query 1888 VCTEIDPKLDNYYKKDNSYFTEQPIDL-VPNQPYPNASFDNFKFVCDNIKFADDLNQLTG 1946
E P L YY Y+T++ I + + NFK + + D LN G
Sbjct 1882 KKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGVYTNFKLIGHTV--CDSLNSKLG 1939
Query 1947 YKKPA-SRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVW--HVNNATNKATY 2003
+ E K+T +P GDVV + Y +++G KP++W H + N TY
Sbjct 1940 FDSSKEFVEYKITEWPTATGDVVLANDDLYVKRYERGCITFGKPVIWLSHEKASLNSLTY 1999
Query 2004 KPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLE 2063
++ + N FDVLK +D + + K E I L
Sbjct 2000 ----------FNRPLLVDDNKFDVLKVDDVDDSGDSSESGAK-------ETKEINIIKLS 2042
Query 2064 CNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTL- 2122
K +V +I+ + K + + D+ ++ ++ N LSR + + T+
Sbjct 2043 GVKKPFKVEDSVIVNDDTSETKYVKSLSIVDVYDMWLTGCKYVVRTANALSRAVNVPTIR 2102
Query 2123 --ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLC 2180
G+ V S+P D + VV N + C N++ + F LL
Sbjct 2103 KFIKFGMTLV-SIPIDLLNLREIKPAVNVVKAVRNKTS-----ACFNFIKWLFVLLFGWI 2156
Query 2181 TFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINII--IWFLLLSV 2238
+ K T IA + + +F K ++ II I+ L +
Sbjct 2157 KISA----DNKVIYTTEIASKLTCKLVALAFKNAFLTFKWSMVARGACIIATIFLLWFNF 2212
Query 2239 CLGSLIYSTAALG--------------VLMSNLGMPSYCTGYREGYLNSTNVTIATYCTG 2284
++I+S L + + + + C Y + YC G
Sbjct 2213 IYANVIFSDFYLPKIGFLPTFVGKIAQWIKNTFSLVTICDLYSIQDVGF----KNQYCNG 2268
Query 2285 SIPCSVCLSGLDSLDTYPSLETIQITISS--FKWDLTAFGLVAEWFLAYILFTRFFYVLG 2342
SI C CL+G D LD Y +++ +Q F +V E ++Y L+T +FY L
Sbjct 2269 SIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLF 2328
Query 2343 LAAIMQLFFSYFAVHFISNS--WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHV 2400
+Q+ ++ F+ ++ W L++ L M P +R YI ASF ++ + HV
Sbjct 2329 ALISIQILTTWLPELFMLSTLHWSFRLLVALANMLPAHVFMRFYIIIASFIKLFSLFKHV 2388
Query 2401 VDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCA 2460
GC+ S C+ CYKRNR+ RV+C+TIV G+ R + V ANGG GFC H WNC++CD++
Sbjct 2389 AYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKP 2448
Query 2461 GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSH 2520
G+TFI+ E A DLS + KRPI PTD + + V V S+ L++D+ GQ+ Y+ + S
Sbjct 2449 GNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCSMRLFYDRDGQRIYDDVNASL 2508
Query 2521 FVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDV 2580
FV+ NL + K ++V+V + + ++++ +A+V+Y+Q + +PIL++D+ L++
Sbjct 2509 FVDYSNLLHSKVKSVPNMHVVVVENDA--DKANFLNAAVFYAQSLFRPILMVDKNLITTA 2566
Query 2581 GDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQG 2640
V MFD YV+TF S F+V + L L+ATA + + + + VL TF+S AR+
Sbjct 2567 NTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQIYKVLDTFLSCARKS 2626
Query 2641 F-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHI 2699
+DSDV+TK + + + + + +E+T +SCNN + TY K +N+ DLG I SA+H+
Sbjct 2627 CSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKSDNIVAADLGVLIQNSAKHV 2686
Query 2700 NAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIA 2759
VAK ++ IW+V F S + +++ A K L KLT V+V+TT +
Sbjct 2687 QGNVAKIAGVSCIWSVDAFNQFSSDFQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFS 2746
Query 2760 LKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRD 2819
LKGG + + ++ ++LV + + P + + K YK +D GV RD
Sbjct 2747 LKGGAVFSYFVYVCFVLSLVCFI---GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRD 2803
Query 2820 IASTDTCFANKHADFDTWFSQRGG--SYTNDKACPLIAAVITREVGFVVPGLPGTILRTT 2877
++ D CFANK FD W+ G Y+N ACP++ AVI ++ G V +P +LR
Sbjct 2804 VSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACPIVVAVIDQDFGSTVFNVPTKVLRY- 2862
Query 2878 NGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTN 2937
LHF+ SA G CYTP I Y++F S CVL++ CT+F A G P PYCY
Sbjct 2863 GYHVLHFITHALSADGVQCYTPHSQISYSNFYASGCVLSSACTMFTMADGSPQPYCYTDG 2922
Query 2938 VLEGSVAYESLRPDTRYVLMDG-SIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGV 2996
+++ + Y SL P RY L + I+FP EG VRVV T YCR G CE ++ G+
Sbjct 2923 LMQNASLYSSLVPHVRYNLANAKGFIRFPEVLREGLVRVVRTRSMSYCRVGLCEEADEGI 2982
Query 2997 CVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIV 3056
C + +G WVLNNDYYRSLPG FCG D +L+ +F L QP+ L ++AS +AG I+A++
Sbjct 2983 CFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVI 3042
Query 3057 VTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYL 3116
V + YY ++ +RAFG+Y+ VV N +++ ++F +L + VY L VY++ Y Y T Y
Sbjct 3043 VVLVFYYLIKLKRAFGDYTSVVFVNVIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYF 3102
Query 3117 TNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE 3176
+++S + H+QW+VM+ ++P W + YI + + H +W FS R++ + S TFE
Sbjct 3103 PSEISVIMHLQWLVMYGTIMPLWFCLLYIAVVVSNHAFWVFS--YCRKLGTSVRSDGTFE 3160
Query 3177 EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAK 3236
E AL TF++ K+ Y KL++ L +NRYL+LYNKY+Y+SG MDT +YREAAC LAK
Sbjct 3161 EMALTTFMITKDSYCKLKNS--LSDVAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAK 3218
Query 3237 ALNDF-SNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWL 3295
A++ F +N+GSDVLYQPP S++++ LQSG KM P+ KVE C+V VT G TLNGLWL
Sbjct 3219 AMDTFTNNNGSDVLYQPPTASVSTSFLQSGIVKMVNPTSKVEPCVVSVTYGNMTLNGLWL 3278
Query 3296 DDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVD 3355
DD VYCPRHVIC++ DM NP+Y +LL R ++ +F V + L V+ + M+ C+L L V
Sbjct 3279 DDKVYCPRHVICSASDMTNPDYTNLLCRVTSSDFTVLFDRLSLTVMSYQMRGCMLVLTVT 3338
Query 3356 TANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNI 3415
N +TPKY F ++PG+TF+VLA YNG P G + MR ++TIKGSFL GSCGSVG+ I
Sbjct 3339 LQNSRTPKYTFGVVKPGETFTVLAAYNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVI 3398
Query 3416 DYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAV 3475
DCV F YMH +EL TG H GTD G+FYGP+ D Q Q D +VN LAWLYAA+
Sbjct 3399 MGDCVKFVYMHQLELSTGCHTGTDFNGDFYGPYKDAQVVQLPIQDYIQSVNFLAWLYAAI 3458
Query 3476 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELL 3535
+N WF+ ++ DFN+ A+ + + D V + L++ TG+++ + A++K L
Sbjct 3459 LNNCNWFIQSDKCSVEDFNVWALSNGFSQVKSDLV--IDALASMTGVSLETLLAAIKRL- 3515
Query 3536 QNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLV 3595
+NG GR I+GS EDE TP DV +Q +G+ QS R KGT W++ + ++
Sbjct 3516 KNGFQGRQIMGSCSFEDELTPSDVYQQLAGIKLQSKRTRLFKGTVCWIMASTFLFSCIIT 3575
Query 3596 QSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN-MVY 3654
+W++F ++ N F + + + AM+ VKHKH +L +++ P L T+ Y N +V
Sbjct 3576 AFVKWTMFMYVTTNMF-SITFCALCVISLAMLLVKHKHLYLTMYITPVLFTLLYNNYLVV 3634
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVL-LILMTARTVYDDGARRVWTLMN 3713
++ + WL S+ + D V+Y +++ ++ +T R++ D + +
Sbjct 3635 YKHTFRGYVYAWLSYYVPSVE-YTYTDEVIYGMLLLVGMVFVTLRSINHDLFSFIMFVGR 3693
Query 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
++++ Y G+ L++ I + ++ S+ Y+ M +A+ ++ V ++F
Sbjct 3694 LISVFSLWYKGSNLEEEILL--MLASLFGTYTWTTVLSMAVAK-VIAKWVAVNVLYFTDI 3750
Query 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
++ ++L Y F+GY +CY+GLF L+N FR+ LGVY+Y +S QE RYMN+ GL PPKN
Sbjct 3751 PQIKIVLLCYLFIGYIISCYWGLFSLMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKN 3810
Query 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
S +A LN KLLG+GG P I+V+ QSK++DVKC +VVLL+ LQ L V S+SKLW C
Sbjct 3811 SFEALMLNFKLLGIGGVPIIEVSQFQSKLTDVKCANVVLLNCLQHLHVASNSKLWHYCST 3870
Query 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INKLCEEMLDNRATLQAIASE 3947
LHN+IL D + AFEK+ LL VL + AVD I ++C++ + LQA+ SE
Sbjct 3871 LHNEILATSDLSVAFEKLAQLLIVLFANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSE 3930
Query 3948 FSSLPSYAAFATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMAD 4006
F ++ S+ + A++ ++A +G + + LK+L+K+ N+AKS ++RD A+ +KLE+MAD
Sbjct 3931 FVNMASFVEYEVAKKNLDEARFSGSANQQQLKQLEKACNIAKSAYERDRAVAKKLERMAD 3990
Query 4007 QAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTT 4066
A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 3991 LALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLA 4050
Query 4067 AAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPL 4126
A L +++PD + Y D TYA +W+IQ + D+D QL+EIS D + WPL
Sbjct 4051 ANTLNIIVPDKSVYDQIVDNIYVTYAGNVWQIQTIQDSDGTNKQLNEISDDCN----WPL 4106
Query 4127 IVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLAL 4184
++ A R N SA LQNNEL P L+ +G QT T YYN + G+ V A+
Sbjct 4107 VIIANRYNEVSATVLQNNELMPAKLKIQVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAI 4164
Query 4185 LSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLG 4244
LSD+ LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V+G
Sbjct 4165 LSDVDGLKYTKILKDDGN-FVVLELDPPCKFTVQDAKGLKIKYLYFVKGCNTLARGWVVG 4223
Query 4245 SLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGT 4304
++++TVRLQAG ATE +NS++LS CAF+VD K Y D++ GG PI NCVKMLC H GT
Sbjct 4224 TISSTVRLQAGTATEYASNSSILSLCAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGT 4283
Query 4305 GQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFT 4364
G AITV P+A Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV +
Sbjct 4284 GMAITVKPDATTSQDSYGGASVCIYCRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYV 4342
Query 4365 LKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
L + VC VCG W+ CSC + +QS D +FLN
Sbjct 4343 LTHDVCRVCGFWRDGSCSCVST-DTTVQSKDT-NFLN 4377
Score = 635 bits (1638), Expect = 1e-180, Method: Composition-based stats.
Identities = 233/1139 (20%), Positives = 405/1139 (36%), Gaps = 210/1139 (18%)
Query 43 RQHLKDGTCGLVEVE----------KGVLPQLEQPYVFIKRSDA---RTAPHGHVMVEL- 88
+ L+ LV +G P+ +F +RS R + HV +L
Sbjct 94 QDALQSREAVLVTTPLGMSLEACYVRGCNPKGWTMGLFRRRSVCNTGRCTVNKHVAYQLY 153
Query 89 VAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKNGNKGA-------GGHS 135
+ + G+ G +G+ +G ++P + +PV RK + LRK G KGA GG
Sbjct 154 MIDPAGVCLG-AGQFVGWVIP-LAFMPVQSRKFIVPWVMYLRKRGEKGAYNKDHGCGGFG 211
Query 136 YGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDG 195
+ D K D D++ +P F + L+R G YVD C G
Sbjct 212 HVYDFKVEDAYDQVHDEPKGKFSKK---------AYALIRGYRGVKPLLYVDQYGCDYTG 262
Query 196 ---YPLECIKDLLARAGKASC-TLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEK-SYE 250
LE D + KA T S++L F + +AW+ R +
Sbjct 263 SLADGLEAYADKTLQEMKALFPTWSQELPF-------------DVIVAWHVVRDPRYVMR 309
Query 251 LQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGFMG--- 298
LQ+ I D +G P V+ +SII + + L M
Sbjct 310 LQSAATICSVAYVANPTEDLCDGSVVIKEPVHVYADDSII------LRQYNLFDIMSHFY 363
Query 299 -----RIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCEF-CGTENLT 350
+ + Y VA +C + + C D C W G+ + CG
Sbjct 364 MEADTVVNAFYGVA-LKDCGFVMQFGYIDCEQDSCDFKGWIPGNMIDGFACTTCGHVYEV 422
Query 351 KEG-ATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGC 409
+ A + G LP N V+ A + G + S Y G + FGGC
Sbjct 423 GDLIAQSSGVLPVNPVLHTKSAAGYGG-FGCKDSFTLY------------GQTVVYFGGC 469
Query 410 VFSYVGCHNKCAYWVPRASANI----GCNHTGVVGEGSEGLNDNL-LEILQKEKVNINIV 464
V+ + N W+P +++ +TGV+G + NL + L + V +
Sbjct 470 VY-WSPARN---IWIPILKSSVKSYDSLVYTGVLGCKAIVKETNLICKALYLDYVQ-HKC 524
Query 465 GDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNI- 523
G+ E + + S ++ +K ++E+ F + + K + +
Sbjct 525 GNLHQRELLGV---------SDVWHKQLLINRGVYKPLLENIDYFNMRRAKFSLETFTVC 575
Query 524 --GEQKSILSPLY-----------AFASEAARVVRSIFSRTLETAQNSVRVLQKAAITIL 570
G +L L AF A ++ ++ S++ E S+ L AAI L
Sbjct 576 ADGFMPFLLDDLVPRAYYLAVSGQAFCDYADKLCHAVVSKSKELLDVSLDSL-GAAIHYL 634
Query 571 DGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDW 630
+ +++D SD T+ +V + T+ L VL
Sbjct 635 NS------KIVDLAQHFSDFGTS-------FVSKIVHFFKTFTTSTALAFAWVLFHVLHG 681
Query 631 LEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCA 690
+ + F+++ I ++ S V + AK + +S++ F +
Sbjct 682 AYIVVESDIYFVKN---IPRYASA-----VAQAFQSVAKVVLDSLRVTFIDGLSCFKIGR 733
Query 691 DSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMP---LKAPKEIIFLEGETL 747
I + G K+ + G + HS L + L MP KA ++ I+L+G
Sbjct 734 RRICLSGRKIYEVERG---LLHSSQL------PLDVYDLTMPSQVQKAKQKPIYLKGSGS 784
Query 748 PTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMM 807
+ V + T L P E P V +CI + + + Y + + +
Sbjct 785 DFSLADSVVEVVTTSLTPCGYS-----EPPKVADKICIVDNVYMAKAGDKYYPVVVDDHV 839
Query 808 VTNNTFTLKGGAPTKVTFGDDTVIE--VQGYKSVNITFELDERIDKVLNEKCSAYTVELG 865
+ A +VTF + ++ + K + + +ELD + +LN C + V+
Sbjct 840 GLLDQAWRVPCAGRRVTFKEQPTVKEIISMPKIIKVFYELDNDFNTILNTACGVFEVDDT 899
Query 866 TEVNEFACVVADAVIKTLQPVSEL---LTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
++ EF VV DA+ + L P EL + L + +LFDE+GE A +YC
Sbjct 900 VDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNPLFLFDEAGEEVFAPKLYC 959
Query 923 SFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQE--EDWL 980
+F P++D+ + + EE + + T G A + EE E ED L
Sbjct 960 AFTAPEDDDFLEESDVEEDDVEGEETDLTI-------TSAGQPCVASEQEESSEVLEDTL 1012
Query 981 DDDSQQTVGQQDGSEDNQTT----TIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTD 1036
DD ED + + I + + T + ++V +
Sbjct 1013 DDGPSVETSDSQVEEDVEMSDFVDLESVIQDYENVCFEFYTTEPEFVKVLGLYVPKATRN 1072
Query 1037 NVYIKNADIV---------------------EEAKKVKPTVVVN--AANVYLKHGGGVA 1072
N ++++ V ++ ++ +VN AN+ L GG VA
Sbjct 1073 NCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVNKIPANIVLPQGGYVA 1131
Score = 191 bits (485), Expect = 3e-46, Method: Composition-based stats.
Identities = 59/251 (24%), Positives = 109/251 (43%), Gaps = 17/251 (7%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
+T NV DI++ +K VK VVVN AN ++ HGGGVA A+ A E+ + +
Sbjct 1272 CITPNVCFVKGDIIKVSKLVKAEVVVNPANGHMVHGGGVAKAIAVAAGQQFVKETTNMVK 1331
Query 1093 TNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLLS 1150
+ G G V +G L K L+VVGP+ + LL+ Y++FN ++ ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYVLLERVYKHFNNYDCVVTTLIS 1391
Query 1151 AGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPKE 1209
AGIF SL + T + V L ++ +D + ++ K++ +++
Sbjct 1392 AGIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLISKCQITAVEGTKKLAARLSFNVGR 1451
Query 1210 EVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL------YIDINGNL 1263
+ +K + L++ L ++ L ++ N ++
Sbjct 1452 SIVYETDANKLILINDVA--------FVSTFNVLQDVLSLRHDIALDDDARTFVQSNVDV 1503
Query 1264 HPDSATLVSDI 1274
P+ +V+
Sbjct 1504 LPEGWRVVNKF 1514
Score = 49.3 bits (116), Expect = 0.002, Method: Composition-based stats.
Identities = 34/150 (23%), Positives = 61/150 (41%), Gaps = 16/150 (11%)
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
++ +V GL K NNC+L + L +Q++ +F LQD + + + F ++
Sbjct 1057 EFVKVLGLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1717 Y--CNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
N + + G V + + L + V C C LKG++A+ + G +
Sbjct 1117 KIPANIVLPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1775 SYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
V C CG+ L+ + PF
Sbjct 1173 --------VSHICKCGESMV--LIDVDVPF 1192
>sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=1a PE=3 SV=1
Length=4441
Score = 3491 bits (9051), Expect = 0.0, Method: Composition-based stats.
Identities = 1063/2942 (36%), Positives = 1601/2942 (54%), Gaps = 121/2942 (4%)
Query 1512 KDWSYSGQ-STQLGIEFLKR----GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLRE 1564
KDW + G++ +K + + DG T + + LL+
Sbjct 1563 KDWRLINKFDVINGVKTVKYFECPNSIYICSQGKDFGYVCDGSFYKATVNQVCVLLA--- 1619
Query 1565 VRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPND 1624
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1620 -KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENL 1678
Query 1625 DTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQ 1684
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1679 SLADISAVQSSFGFDQQQLLAYYNFL-TVCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQ 1737
Query 1685 QIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSC 1744
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1738 HINLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGA 1797
Query 1745 KRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF
Sbjct 1798 ICELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPF 1855
Query 1805 VMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPIT 1864
++ S P +L A+ + G GHY H+ D + K + G +T
Sbjct 1856 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1913
Query 1865 DVFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP-- 1921
D Y +N + T T Y LD V +P L YY + Y+T +PI +P+
Sbjct 1914 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKV 1972
Query 1922 NASFDNFKFVCDNIKFADDLNQLTGYKKP-ASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
+ + NFK V +I LN G+ E KVT +P GDVV Y +
Sbjct 1973 DGVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYF 2030
Query 1981 KGAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDN 2038
KG + KP++W H + N TY ++ ++ N + VL D+
Sbjct 2031 KGCETFGKPVIWLCHDEASLNSLTY----------FNKPSFKSENRYSVLSV------DS 2074
Query 2039 LACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMA 2097
++ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2075 VSEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWD 2134
Query 2098 AYVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT 2154
Y+ + NELSR++ T+ +G+ + ++P D + N+ +
Sbjct 2135 MYLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRDD---NQTLLVPK 2190
Query 2155 NIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEAS 2214
R + ++ + F + L FT T IA ++ L+ +
Sbjct 2191 IFKARAIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNA 2244
Query 2215 FNYLKSPNFSKLIN-----IIIWF--LLLSVCLGSL---------IYSTAALGVLMSNLG 2258
F + F K + WF L ++V I+ + + + G
Sbjct 2245 FQTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFG 2304
Query 2259 MPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKW-- 2316
+ + C Y + + T+ +C GS C +C SG D LDTY +++ +Q +
Sbjct 2305 LVTICDFYSKLGVGFTS----HFCNGSFICELCYSGFDMLDTYAAIDFVQYEVDRRVLFD 2360
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2361 YVSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2420
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2421 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2480
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2481 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2540
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + + + ++
Sbjct 2541 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVESDA--DRANF 2598
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2599 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVN 2658
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2659 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2718
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK+ NI+ IW + F L+ L+ +++ A
Sbjct 2719 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDTFNQLTADLQHKLKKAC 2778
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L ++L+ + + + P
Sbjct 2779 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPT 2835
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ G Y N C
Sbjct 2836 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSFYYHNSMDC 2895
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2896 PIVVAVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2954
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2955 GCVLSSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 3014
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 3015 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQF 3074
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3075 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFL 3134
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3135 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3194
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N + STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3195 NHVLWLFS--YCRKIGVNVCNDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3250
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3251 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3310
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC S +M P+Y LL R + +F
Sbjct 3311 VSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDF 3370
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3371 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAF 3430
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3431 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYR 3490
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ ++ DFN+ AM + + D
Sbjct 3491 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADL 3550
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3551 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3607
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + + ++ +F M+ V
Sbjct 3608 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYINTH-MIGVTLCVLCFVSFMMLLV 3666
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3667 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGLTYVWLSYFVPAVNFTYVYEVFYGCIL 3726
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3727 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTWTT 3784
Query 3749 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 3808
+ +A+ IV + +F ++ I+L Y F+GY +CY+G F LLN FR+ +
Sbjct 3785 ILSLAIAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPM 3843
Query 3809 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCT 3868
GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3844 GVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCA 3903
Query 3869 SVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD-- 3926
+VVLL+ LQ L V S+S+LW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3904 NVVLLNCLQHLHVASNSRLWQYCSILHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDTK 3963
Query 3927 ----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLK 3981
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L+
Sbjct 3964 CLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLE 4023
Query 3982 KSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLD 4041
K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLD
Sbjct 4024 KACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 4083
Query 4042 NDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQV 4101
N ALN+I++NA GCVPLN IP A L ++IPD + D YA ++W IQ V
Sbjct 4084 NQALNSILDNAVKGCVPLNAIPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQTV 4143
Query 4102 VDADSKIVQLSEISMDNSPNLAWPLIVTALRANS--AVKLQNNELSPVALRQMSCAAGTT 4159
DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4144 QDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSD 4199
Query 4160 QTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDT 4219
YYN GR V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4200 MNCNIPTQ--CYYNNGSSGRIVYAVLSDVDGLKYTKIIKDDGNCVV-LELDPPCKFSIQD 4256
Query 4220 PKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKA 4279
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VD K
Sbjct 4257 VKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKT 4316
Query 4280 YKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNP 4339
Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+
Sbjct 4317 YLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDV 4376
Query 4340 KGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSF 4399
G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D +F
Sbjct 4377 DGLCKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SGVAVQSKDL-NF 4433
Query 4400 LN 4401
LN
Sbjct 4434 LN 4435
Score = 435 bits (1119), Expect = 4e-120, Method: Composition-based stats.
Identities = 196/1058 (19%), Positives = 367/1058 (35%), Gaps = 190/1058 (18%)
Query 13 HVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGVLPQLEQPYVFIK 72
HVQ +L +RD+ V + + V + +K GT L++ L + YV
Sbjct 71 HVQSNL----IRDIFVH---EDLHVVEVLTKTAVKSGTAILIKSPLHSLGGFPKGYVMGL 123
Query 73 RSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKN 126
+T +V+ L +G LG +VP G +P K + ++
Sbjct 124 FRSYKTK--RYVVHHLSMTTSTTNFGED--FLGWIVPF-GFMPSYVHKWFQFCRLYIEES 178
Query 127 GNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYV 186
+ D D E+ +P + + L+R+ G +V
Sbjct 179 DLIISNFKFDDYDFSVEDAYAEVHAEPKGKYSQK---------AYALLRQYRGIKPVLFV 229
Query 187 DNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSE 246
D C G +C++ +L + + + +AW+ R
Sbjct 230 DQYGCDYSGKLADCLQAY------GHYSLQDMRQKQSVW---LANCDFDIVVAWHVVRDS 280
Query 247 K-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGF 296
+ LQT I K D +G P + ++I+ + P + K
Sbjct 281 RFVMRLQTIATICGIKYVAQPTEDVVDGAVVIREPVHLLSADAIVLKL-PSLMKVMTHMD 339
Query 297 MGRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCE-FCGTENLTKE- 352
I+S+Y V +C + + C D+C W +G+ + C T + E
Sbjct 340 DFSIKSIYNV-DLCDCGFVMQYGYVDCFNDNCDFYGWVSGNMMDGFSCPLCCTVYDSSEV 398
Query 353 GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFS 412
A + G +P+N V+ + + G FG C++
Sbjct 399 KAQSSGVIPENPVL-----------------FTNSTDTVNPDSFNLYGYSVTPFGSCIY- 440
Query 413 YVGCHNKCAYWVPRASANIGC----NHTGVVGEGSEGLNDNLL-EILQKEKVNINIVGDF 467
+ W+P +++ ++GVVG S L+ L + V G+
Sbjct 441 WSPRPG---LWIPIIKSSVKSYDDLVYSGVVGCKSIVKETALITHALYLDYVQC-KCGNL 496
Query 468 KLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQK 527
+ N + G++ +Q++ + G++ +
Sbjct 497 EQNH-------------------ILGVNNSWCRQLLLNRGDYNM---------------- 521
Query 528 SILSPLYAFASEAARVVRSIFSRTLETAQNSVRV------------LQKAAITILDGISQ 575
+L + F R+ F+ + L ++ I +SQ
Sbjct 522 -LLKNIDLFVKR-----RADFACKFAVCGDGFVPFLLDGLIPRSYYLIQSGIFFTSLMSQ 575
Query 576 YSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW----------LTNIFGTVYEKL 624
+S + D + L + + V YI V +L +Q+ + N F T+ +
Sbjct 576 FSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDAS 635
Query 625 KPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNK 684
P WL + G+ F+ + A I AK + TFFKL+
Sbjct 636 APATGWLLYQLLNGL-----------FVVSQANFNFVALIPDYAKILVNKFYTFFKLL-- 682
Query 685 FLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSREETGLLMPLKA-PKE 738
L ++ LK +N +G F S GL G ++P A ++
Sbjct 683 -LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI---------PGFVLPCNAQEQQ 732
Query 739 IIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTPVCINGLMLLEIKDT 796
I F EG + E V+++ ++ ++ S E + P +CI M +
Sbjct 733 IYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGD 785
Query 797 EKYCALAPNMMV-TNNTFTLKGGAPTKVTFGDDTVI-EVQGYKSVNITFELDERIDKVLN 854
+ + + + + + A KV F + V+ E+ +V + F+LD D +L
Sbjct 786 KFFPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILG 845
Query 855 EKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDES 911
+ CS + VE G V++F VV DA+ L + + + L++ + YLFDE+
Sbjct 846 KVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKDHPVVGYQVRAFLNKLNENVVYLFDEA 905
Query 912 GEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQ 970
G+ +AS MYC+F D ED + E+ + + ++D +
Sbjct 906 GDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDDED---VVTGDNDDEDVVT 962
Query 971 PEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEV 1008
+ + E+ D+ + V D +++ T +V
Sbjct 963 GDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDV 1000
Score = 197 bits (501), Expect = 3e-48, Method: Composition-based stats.
Identities = 64/254 (25%), Positives = 106/254 (42%), Gaps = 17/254 (7%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A E+ +
Sbjct 1328 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1387
Query 1092 ATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQHEVLLAPLL 1149
+ G +VG V +G L K L++VGP+ + LL AY++ N ++ L+ L+
Sbjct 1388 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1447
Query 1150 SAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVEQKIAEIPK 1208
SAGIF SL + V V L +K +D + + K + ++
Sbjct 1448 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDIIQKCQITSVVGTKALAVRLTANVG 1507
Query 1209 EEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDI------NGN 1262
+K K + C ++ ++E L ++ L D+
Sbjct 1508 RVIKFETDAYKLFLSGD--------DCFVSNSSVIQEVLLLRHDIQLNNDVRDYLLSKMT 1559
Query 1263 LHPDSATLVSDIDI 1276
P L++ D+
Sbjct 1560 SLPKDWRLINKFDV 1573
Score = 54.3 bits (129), Expect = 7e-05, Method: Composition-based stats.
Identities = 42/200 (21%), Positives = 73/200 (37%), Gaps = 21/200 (11%)
Query 1597 TYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKW 1656
D D + + + ++ Y L V D ++S + +
Sbjct 1061 VTGDNDDQIVVTGDDVDDIESVYDFDTYKALLV-------FNDVYNDALFVSYGSSVETE 1113
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1114 TYFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLT 1173
Query 1717 YCNKTVGEL--GDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
K + G V + + ++ N C CG L G++AV + G +
Sbjct 1174 TIPKAIVLPQGGYVADFAYWFLNQFDI---NAYANWCCLKCGF-SFDLNGLDAVFFYGDI 1229
Query 1775 SYEQFKKGVQIPCTCGKQAT 1794
V C CG T
Sbjct 1230 --------VSHVCKCGHNMT 1241
>sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=1a PE=1 SV=1
Length=4471
Score = 3485 bits (9037), Expect = 0.0, Method: Composition-based stats.
Identities = 1067/2942 (36%), Positives = 1602/2942 (54%), Gaps = 121/2942 (4%)
Query 1512 KDWSYSGQ-STQLGIEFLKR----GDKSVYYTSNPTTFHLDGEV--ITFDNLKTLLSLRE 1564
KDW + G++ +K + + DG T + + LL+
Sbjct 1593 KDWRLINKFDVINGVKTVKYFECPNSIYICSQGKDFGYVCDGSFYKATVNQVCVLLA--- 1649
Query 1565 VRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPND 1624
+ I V TVD +N + + + +G+ G + DG DVTK+K + + K Y N
Sbjct 1650 -KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENL 1708
Query 1625 DTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQ 1684
+ A + D L Y + L KW S + + NNCY+ A L LQ
Sbjct 1709 SLADISAVQSSFGFDQQQLLAYYNFL-TVCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQ 1767
Query 1685 QIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSC 1744
I LKFN Q+A+Y RAG AL+LA + E D + + + + A+L
Sbjct 1768 HINLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGA 1827
Query 1745 KRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPF 1804
L ++C CG +Q + GV+AVM+ GTL+ G +I C C + + + PF
Sbjct 1828 ICELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGRIV-HCTKLNVPF 1885
Query 1805 VMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPIT 1864
++ S P +L A+ + G GHY H+ D + K + G +T
Sbjct 1886 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1943
Query 1865 DVFYKEN-SYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYP-- 1921
D Y +N + T T Y LD V +P L YY + Y+T +PI +P+
Sbjct 1944 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKV 2002
Query 1922 NASFDNFKFVCDNIKFADDLNQLTGYKKP-ASRELKVTFFPDLNGDVVAIDYKHYTPSFK 1980
+ + NFK V +I LN G+ E KVT +P GDVV Y +
Sbjct 2003 DGVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYF 2060
Query 1981 KGAKLLHKPIVW--HVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDN 2038
KG + KP++W H + N TY ++ ++ N + VL D+
Sbjct 2061 KGCETFGKPVIWFCHDEASLNSLTY----------FNKPSFKSENRYSVLSV------DS 2104
Query 2039 LACEDLKPVSEEVVENPTIQKDV-LECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMA 2097
++ E V V+E+ K+V L+ KT ++ II+ N+S+K+ + + D+
Sbjct 2105 VSEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWD 2164
Query 2098 AYVDNSSLTIKKPNELSRVLGLKTL---ATHGLAAVNSVPWDTIANYAKPFLNKVVSTTT 2154
Y+ + NELSR++ T+ +G+ + ++P D + N+ +
Sbjct 2165 MYLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPI-TIPIDLLCLRDD---NQTLLVPK 2220
Query 2155 NIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEAS 2214
R + ++ + F + L FT T IA ++ L+ +
Sbjct 2221 IFKARAIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNA 2274
Query 2215 FNYLKSPNFSKLIN-----IIIWF--LLLSVCLGSL---------IYSTAALGVLMSNLG 2258
F + F K + WF L ++V I+ + + + G
Sbjct 2275 FQTFRWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFG 2334
Query 2259 MPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKW-- 2316
+ + C Y + + T+ +C GS C +C SG D LDTY +++ +Q +
Sbjct 2335 LVTICDFYSKLGVGFTS----HFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFD 2390
Query 2317 DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNS--WLMWLIINLVQM 2374
++ L+ E + Y L+T +FY L +QLF ++ F+ + WL+ I+ + M
Sbjct 2391 YVSLVKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANM 2450
Query 2375 APISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSF 2434
P ++R YI + Y V H+V GCN + C+ CYKRN + RV+C+TIV GV R +
Sbjct 2451 LPAFVLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYY 2510
Query 2435 YVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2494
+ ANGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2511 DITANGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDI 2570
Query 2495 TVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSA 2554
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + + + ++
Sbjct 2571 KQVGCMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVESDA--DRANF 2628
Query 2555 KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVA 2614
+A V+Y+Q + +PILL+D+ L++ + V MFD YV+TF S F+V + V
Sbjct 2629 LNAVVFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVN 2688
Query 2615 TAEAELAKNVSLDNVLSTFISAARQGF-VDSDVETKDVVECLKLSHQSDIEVTGDSCNNY 2673
A A L + V L+ VL TF+ R+ +DSDVET+ + + + + + +E T ++ NN
Sbjct 2689 IAHASLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNL 2748
Query 2674 MLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAA 2733
+ TY K +N+ DLG I A+H+ VAK+ NI+ IW + F L+ L+ +++ A
Sbjct 2749 VPTYLKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDAFNQLTADLQHKLKKAC 2808
Query 2734 KKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPV 2793
K L KLT V ++TT +LKGG +++N L L V+L+ + + + P
Sbjct 2809 VKTGLKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFVSLICFI---LLWALLPT 2865
Query 2794 HVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGG--SYTNDKAC 2851
+ + K +K ID GV RDI+ D CFANK FD W+ G Y N C
Sbjct 2866 YSVYKSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDC 2925
Query 2852 PLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATS 2911
P++ AV+ ++G + +P +LR LHFL F++ CYTP I Y DF S
Sbjct 2926 PIVVAVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYAS 2984
Query 2912 ACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGS-IIQFPNTYLE 2970
CVL++ CT+FK G P PYCY V++ + Y SL P TRY L + + I+FP+ E
Sbjct 2985 GCVLSSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISE 3044
Query 2971 GSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNM 3030
G VR+V T YCR G CE +E G+C + + WVLNNDYYRS+PG FCG D +L
Sbjct 3045 GIVRIVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQF 3104
Query 3031 FTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFT 3090
F+ LI+PI ++AS + G I+AIVV + YY ++ +RAFG+Y+ VV N +++ ++F
Sbjct 3105 FSSLIRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVVVWCINFL 3164
Query 3091 VLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICIST 3150
+L + VY VY+ Y Y+T Y +++S + H+QW+VM+ ++PFW + Y+ +
Sbjct 3165 MLFVFQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIA 3224
Query 3151 KHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLAL 3210
H W FS R++ N S STFEE +L TF++ K+ Y +L++ V YNRYL+L
Sbjct 3225 NHVLWLFS--YCRKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNSV--SDVAYNRYLSL 3280
Query 3211 YNKYKYFSGAMDTTSYREAACCHLAKALNDFS-NSGSDVLYQPPQTSITSAVLQSGFRKM 3269
YNKY+Y+SG MDT +YREAAC LAKA+ F+ N+G+DVLYQPP S++++ LQSG KM
Sbjct 3281 YNKYRYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKM 3340
Query 3270 AFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNF 3329
P+ K+E C+V VT G+ TLNGLWLDD VYCPRHVIC+S +M P+Y LL R + +F
Sbjct 3341 VSPTSKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICSSSNMNEPDYSALLCRVTLGDF 3400
Query 3330 LVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVY 3389
+ +G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G +
Sbjct 3401 TIMSGRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGNVKPGETFTVLAAYNGRPQGAF 3460
Query 3390 QCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFV 3449
MR ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD GNFYGP+
Sbjct 3461 HVTMRSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYR 3520
Query 3450 DRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDH 3509
D Q Q D TVNV+AWLYAA++N WF+ + DFN+ AM + + D
Sbjct 3521 DAQVVQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSTEDFNVWAMANGFSQVKADL 3580
Query 3510 VDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ 3569
V L L++ TG+++ + A++K L G GR ILGS EDE P DV +Q +GV Q
Sbjct 3581 V--LDALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQ 3637
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFV 3629
S KR IK T +W+L++ ++ +W++F ++ + + + ++ +F M+ V
Sbjct 3638 SKTKRFIKETIYWILISTFLFSCIISAFVKWTIFMYINTH-MIGVTLCVLCFVSFMMLLV 3696
Query 3630 KHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASA 3688
KHKH +L ++++P L T+ Y N +V + WL +++ + +
Sbjct 3697 KHKHFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSYFVPAVNFTYVYEVFYGCIL 3756
Query 3689 VVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVV 3748
V I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ I + Y+
Sbjct 3757 CVFAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTWTT 3814
Query 3749 TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTL 3808
+ +A+ IV + +F ++ I+L Y F+GY +CY+G F LLN FR+ +
Sbjct 3815 ILSLAIAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPM 3873
Query 3809 GVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCT 3868
GVY+Y +S QE RYMN+ GL PP+NS +A LN+KLLG+GG P I+V+ +QSK++DVKC
Sbjct 3874 GVYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCA 3933
Query 3869 SVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD-- 3926
+VVLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3934 NVVLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDTK 3993
Query 3927 ----INKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGD-SEVVLKKLK 3981
I+++ ++ + + LQA+ SEF ++ S+ + A++ A +G ++ +K+L+
Sbjct 3994 CLASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLE 4053
Query 3982 KSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLD 4041
K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLD
Sbjct 4054 KACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLD 4113
Query 4042 NDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQV 4101
N ALN+I++NA GCVPL+ IP A L +VIPD + D TYA ++W IQ V
Sbjct 4114 NQALNSILDNAVKGCVPLSAIPALAANTLTIVIPDKQVFDKVVDNVYVTYAGSVWHIQTV 4173
Query 4102 VDADSKIVQLSEISMDNSPNLAWPLIVTALRANS--AVKLQNNELSPVALRQMSCAAGTT 4159
DAD QL++IS+D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4174 QDADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSD 4229
Query 4160 QTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDT 4219
YYN GR V A+LSD+ LK+ + K DG + EL+PPC+F
Sbjct 4230 MNCNIPTQ--CYYNNGSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFSIQD 4286
Query 4220 PKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKA 4279
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VD K
Sbjct 4287 VKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKT 4346
Query 4280 YKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNP 4339
Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+
Sbjct 4347 YLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDV 4406
Query 4340 KGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSF 4399
G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D +F
Sbjct 4407 DGICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SSVAVQSKDL-NF 4463
Query 4400 LN 4401
LN
Sbjct 4464 LN 4465
Score = 437 bits (1123), Expect = 1e-120, Method: Composition-based stats.
Identities = 197/1058 (19%), Positives = 368/1058 (35%), Gaps = 190/1058 (18%)
Query 13 HVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGVLPQLEQPYVFIK 72
HVQ +L +RD+ V + + V + +K GT L++ L + YV
Sbjct 71 HVQSNL----IRDIFVH---EDLHVVEVLTKTAVKSGTAILIKSPLHSLGGFPKGYVMGL 123
Query 73 RSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVL------LRKN 126
+T +V+ L +G LG +VP G +P K + ++
Sbjct 124 FRSYKTK--RYVVHHLSMTTSTTNFGED--FLGWIVPF-GFMPSYVHKWFQFCRLYIEES 178
Query 127 GNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYV 186
+ D D E+ +P + + L+R+ G +V
Sbjct 179 DLIISNFKFDDYDFSVEDAYAEVHAEPKGKYSQK---------AYALLRQYRGIKPVLFV 229
Query 187 DNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSE 246
D C G +C++ +L + + + +AW+ R
Sbjct 230 DQYGCDYSGKLADCLQAY------GHYSLQDMRQKQSVW---LANCDFDIVVAWHVVRDS 280
Query 247 K-SYELQTPFEIKLAKKF-----DTFNGEC----PNFVFPLNSIIKTIQPRVEKKKLDGF 296
+ LQT I K D +G+ P + ++I+ + P + K
Sbjct 281 RFVMRLQTIATICGIKYVAQPTEDVVDGDVVIREPVHLLSADAIVLKL-PSLMKVMTHMD 339
Query 297 MGRIRSVYPVASPNECNQMCLSTLMKC--DHCGETSWQTGDFVKATCE-FCGTENLTKE- 352
I+S+Y V +C + + C D+C W +G+ + C T + E
Sbjct 340 DFSIKSIYNV-DLCDCGFVMQYGYVDCFNDNCDFYGWVSGNMMDGFSCPLCCTVYDSSEV 398
Query 353 GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFS 412
A + G +P+N V+ + + G FG C++
Sbjct 399 KAQSSGVIPENPVL-----------------FTNSTDTVNHDSFNLYGYSVTPFGSCIY- 440
Query 413 YVGCHNKCAYWVPRASANIGC----NHTGVVGEGSEGLNDNLL-EILQKEKVNINIVGDF 467
+ W+P +++ ++GVVG S L+ L + V G+
Sbjct 441 WSPRPG---LWIPIIKSSVKSYDDLVYSGVVGCKSIVKETALITHALYLDYVQC-KCGNL 496
Query 468 KLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQK 527
+ N + G++ +Q++ + G++ +
Sbjct 497 EQNH-------------------ILGVNNSWCRQLLLNRGDYNM---------------- 521
Query 528 SILSPLYAFASEAARVVRSIFSRTLETAQNSVRV------------LQKAAITILDGISQ 575
+L + F R+ F+ + L ++ I +SQ
Sbjct 522 -LLKNIDLFVKR-----RADFACKFAVCGDGFVPFLLDGLIPRSYYLIQSGIFFTSLMSQ 575
Query 576 YSLRLIDAMMFTSDLATNNLVVMA-YITGGVVQLTSQW----------LTNIFGTVYEKL 624
+S + D + L + + V YI V +L +Q+ + N F T+ +
Sbjct 576 FSQEVSDMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDAS 635
Query 625 KPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNK 684
P WL + G+ F+ + A I AK + TFFKL+
Sbjct 636 APATGWLLYQLLNGL-----------FVVSQANFNFVALIPDYAKILVNKFYTFFKLL-- 682
Query 685 FLALCADSIIIGGAKLKALN-----LGETFVTHSKGLYRKCVKSREETGLLMPLKA-PKE 738
L ++ LK +N +G F S GL G ++P A ++
Sbjct 683 -LECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGLI---------PGFVLPCNAQEQQ 732
Query 739 IIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTS--EAVEAPLVGTPVCINGLMLLEIKDT 796
I F EG + E V+++ ++ ++ S E + P +CI M +
Sbjct 733 IYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGD 785
Query 797 EKYCALAPNMMV-TNNTFTLKGGAPTKVTFGDDTVI-EVQGYKSVNITFELDERIDKVLN 854
+ + + + + + A KV F + V+ E+ +V + F+LD D +L
Sbjct 786 KFFPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILG 845
Query 855 EKCSAYTVELGTEVNEFACVVADAVIKTLQPVSE---LLTPLGIDLDEWSMATYYLFDES 911
+ CS + VE G V++F VV DA+ L E + + L++ + YLFDE+
Sbjct 846 KVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQVRAFLNKLNENVVYLFDEA 905
Query 912 GEFKLASHMYCSFYPPD-EDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQ 970
G+ +AS MYC+F D ED + E+ + + ++D +
Sbjct 906 GDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDDED---VVTGDNDDEDVVT 962
Query 971 PEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEV 1008
+ + E+ D+ + V D +++ T +V
Sbjct 963 GDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDV 1000
Score = 197 bits (502), Expect = 2e-48, Method: Composition-based stats.
Identities = 66/262 (25%), Positives = 109/262 (42%), Gaps = 18/262 (7%)
Query 1024 EVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAM 1083
E+ G L +T NV DI+ A+ VK V+VN AN ++ HGGGVA A+ A
Sbjct 1351 ELPQLYG-LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKF 1409
Query 1084 QVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVN--KGEDIQLLKSAYENFNQH 1141
E+ + + G +VG V +G L K L++VGP+ + LL AY++ N +
Sbjct 1410 SKETAAMVKSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNY 1469
Query 1142 EVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVS-SFLEMKSEKQVE 1200
+ L+ L+SAGIF SL + V V L +K +D + + K +
Sbjct 1470 DCCLSTLISAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDIIQKCQITSVVGTKALA 1529
Query 1201 QKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDI- 1259
++ +K K + C ++ ++E L ++ L D+
Sbjct 1530 VRLTANVGRVIKFETDAYKLFLSGD--------DCFVSNSSVIQEVLLLRHDIQLNNDVR 1581
Query 1260 -----NGNLHPDSATLVSDIDI 1276
P L++ D+
Sbjct 1582 DYLLSKMTSLPKDWRLINKFDV 1603
Score = 52.8 bits (125), Expect = 2e-04, Method: Composition-based stats.
Identities = 41/200 (21%), Positives = 73/200 (37%), Gaps = 21/200 (11%)
Query 1597 TYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKW 1656
D D + + + ++ Y L V D ++S + +
Sbjct 1091 VTGDNDDQIVVTGDDVDDIESIYDFDTYKALLV-------FNDVYNDALFVSYGSSVETE 1143
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
Y +VNGL S NC+L + LL +Q++ KF A+++ + + G +F +L
Sbjct 1144 TYFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLT 1203
Query 1717 YCNKTVGEL--GDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTL 1774
K + G V + + ++ N C CG L G++A+ + G +
Sbjct 1204 TIPKAIVLPQGGFVADFAYWFLNQFDI---NAYANWCCLKCGF-SFDLNGLDALFFYGDI 1259
Query 1775 SYEQFKKGVQIPCTCGKQAT 1794
V C CG T
Sbjct 1260 --------VSHVCKCGHNMT 1271
>sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=1a PE=3
SV=1
Length=3951
Score = 2677 bits (6938), Expect = 0.0, Method: Composition-based stats.
Identities = 866/2979 (29%), Positives = 1372/2979 (46%), Gaps = 319/2979 (11%)
Query 1549 EVITFDNLKTLLSLREV--RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTK 1606
V+ F + + +V + ++ T D + + V+ + G QFG Y V
Sbjct 1157 RVLLFSLSQEHIDYFDVTCKQKTIYLTEDGVKYRSIVLKPGDSLG-QFGQVYAKNKIV-- 1213
Query 1607 IKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTS 1666
+ + + YV D ++ EYY D Y+ L +KW +
Sbjct 1214 FTADDVEDKEILYVPTTDKSI----LEYYG-LDAQKYVIYLQTL--AQKWNVQYRDNFLI 1266
Query 1667 IKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELG 1726
++W D NC++++A++ LQ +++F L +A+ + G+ +F A A C VG+
Sbjct 1267 LEWRDGNCWISSAIVLLQAAKIRFK-GFLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFS 1325
Query 1727 DVRETMSYLFQHANLDSCKRVLNV-VCKTCGQQQTTLKGVEAVM-YMGTLSYEQFKKGVQ 1784
D ++ L +H + D L V CG + L+G+EA + + + FK
Sbjct 1326 DANWLLANLAEHFDADYTNAFLKKRVSCNCGIKSYELRGLEACIQPVRATNLLHFKTQYS 1385
Query 1785 IPCTCGKQATKYLVQQESPFVMMSAP--PAQYELKHGTFTCASEYTGNYQCGH-YKHITS 1841
TCG T +++ P++++ A PA + + G+ GH Y
Sbjct 1386 NCPTCGANNTDEVIEASLPYLLLFATDGPATVDCDEDAVGT-VVFVGSTNSGHCYTQA-- 1442
Query 1842 KETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYK 1901
D + K P Y ++ K + + N
Sbjct 1443 --AGQAFDNLAKDRKFGKKSPYITAMYTRFAFKNETSLPVAKQSKGKSKSVKEDVSNL-- 1498
Query 1902 KDNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFP 1961
ASFDN D Q Y LKV P
Sbjct 1499 ----------------ATSSKASFDNL----------TDFEQW--YDSNIYESLKVQESP 1530
Query 1962 DLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVET 2021
D ++ Y T + + P T +R + S +
Sbjct 1531 D--------NFDKYVS------------------FTTKEDSKLPLTLKVRGIKSVVDFRS 1564
Query 2022 SNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVK---------TTEVV 2072
+ F + D PV V++ +++ +E N + +
Sbjct 1565 KDGFIYKLTPDTD------ENSKAPVYYPVLDAISLKAIWVEGNANFVVGHPNYYSKSLH 1618
Query 2073 GDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNS 2132
+ A N +K+ +++G + ++ + KPN L R+ + A G + V +
Sbjct 1619 IPTFWENAENFVKMGDKIGGVTMGLWRAEH----LNKPN-LERIFNIAKKAIVGSSVVTT 1673
Query 2133 VPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVC--------TNYMPYFF-TLLLQLCTFT 2183
I A +KV +T + +C P F TL+ L F
Sbjct 1674 QCGKLIGKAATFIADKVGGGVVRNITDSIKGLCGITRGHFERKMSPQFLKTLMFFLFYFL 1733
Query 2184 RSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSL 2243
+++ + AS T + K + ++ +I+WF+ S +
Sbjct 1734 KASVKSVVASYKTVLCKVVLATL----------------------LIVWFVYTS---NPV 1768
Query 2244 IYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPS 2303
+++ + + L S C Y++ +S + YC C VCL DSL Y
Sbjct 1769 MFTGIRV---LDFLFEGSLCGPYKDYGKDS--FDVLRYCADDFICRVCLHDKDSLHLYKH 1823
Query 2304 LETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAIMQLFFSYFAVHFISN 2361
+++ A G + W Y++F F V G I Y + + N
Sbjct 1824 AYSVEQVYKD-----AASGFIFNWNWLYLVFLILFVKPVAGFVII-----CYCVKYLVLN 1873
Query 2362 SWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVVDGCNSSTCMMCYKRN 2416
S ++ + + + + + F + +Y W Y VH + C TC +C +
Sbjct 1874 STVLQTGVCFLDWF-VQTVFSHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVA 1932
Query 2417 RATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQ 2476
R+ R E + +V G ++ +VY N G FCK HNW C NCD + +TF+S EVA +LS +
Sbjct 1933 RSNRQEVSVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEK 1992
Query 2477 FKRPINPTDQSSYIVDSVTVKNGSIHLYFDK-AGQKTYERHSLSHFVNLDNLR-ANNTKG 2534
KR + PT + ++VD + + ++L + K ++ F D L+ A K
Sbjct 1993 LKRHVKPTAYAYHVVDEACLVDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKE 2052
Query 2535 SLPINVIVFDGKSKCEESSA------KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAV 2588
+L I DG C SA K+A++YY+Q +C+PIL+LDQAL +
Sbjct 2053 ALKCEQISNDGFIVCNTQSAHALEEAKNAAIYYAQYLCKPILILDQALYEQL-------- 2104
Query 2589 KMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVET 2648
V K+++ + L+ +S+D + + + + S +
Sbjct 2105 ---------------VVEPVSKSVIDKVCSILSSIISVDTAALNYKAGTLRDALLSITKD 2149
Query 2649 KDVVECLKLSHQSDIEVTGDSCNNYMLTY-NKVENMTPRDLGACIDCSARHINAQVAKSH 2707
++ V+ H D++ TGD N + +Y +TPRD G I+ A N +V +
Sbjct 2150 EEAVDMAIFCHNHDVDYTGDGFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAP 2209
Query 2708 NIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL--KGGKI 2765
++W + + LS+ K + SA K+ + F +T + +QV+ T K+ + K G I
Sbjct 2210 --PVVWKFSELIKLSDSCLKYLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGI 2267
Query 2766 VNN---WLKQLIKVTLVFLF-----VAAIFYLITPVHVMSKHTDFSS--EIIGYKAIDGG 2815
V+ K K L+F + +Y+ + D +S + G+K ID G
Sbjct 2268 VSGTFKCFKSYFKWLLIFYILFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKG 2327
Query 2816 VTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILR 2875
V R+I DTCF+NK +FD ++ G Y N + CP++ AVI + G V G+PG +
Sbjct 2328 VLREIVPEDTCFSNKFVNFDAFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSW 2383
Query 2876 TTNG-DFLH---------FLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDA 2925
+G F+H ++P F+ + YT +I F TS + +A C ++ A
Sbjct 2384 VMDGVMFIHMTQTERKPWYIPTWFNRE-IVGYTQDSIITEGSFYTSIALFSARC-LYLTA 2441
Query 2926 SGKPVPYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYC 2984
S P YC++ N G++ + S+ P Y +G + P L V DS YC
Sbjct 2442 SNTPQLYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQILHTPYVVKFVSDS-YC 2500
Query 2985 RHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDIS 3044
R CE + G CVS + +WVL ND Y S PGVFCG L+ +M + + +I
Sbjct 2501 RGSVCEYTRPGYCVSLNPQWVLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIY 2559
Query 3045 ASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGV 3104
+ ++ +VV + ++F+ F Y+ V L+++++ +LC+ S L +
Sbjct 2560 MQLATMFLILVVVVLIFAMVIKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVI 2619
Query 3105 YSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAY---IICISTKHFYWFFSNYL 3161
V+Y Y + + + + H + F +VP W+ Y II + T F W +
Sbjct 2620 LLVLYCYASLVTSRNTVIIMHCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTK 2679
Query 3162 KRRVVFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGA 3220
R +++G F ++ AA TF++ ++KL +++ ++ YL+ Y + KY+SG
Sbjct 2680 NTRKLYDGNEFVGNYDLAAKSTFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGT 2736
Query 3221 MDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCM 3280
Y +A LA AL+ + NSG +++Y PP+ SI + LQSGF+K+ PS VE C+
Sbjct 2737 GSEQDYLQACRAWLAYALDQYRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCI 2796
Query 3281 VQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGN-VQLR 3339
V V+ LNGLWL D +YCPRHV+ + D+L +NH F V + V L
Sbjct 2797 VSVSYRGNNLNGLWLGDTIYCPRHVL---GKFSGDQWNDVLNLANNHEFEVTTQHGVTLN 2853
Query 3340 VIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTI 3399
V+ ++ VL L+ AN +TPKYKF++ G +F++ Y G+ G+Y MR N TI
Sbjct 2854 VVSRRLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTI 2913
Query 3400 KGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGT 3459
+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G FYG +VD + AQ
Sbjct 2914 RASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPP 2973
Query 3460 DTTITVNVLAWLYAAVINGDRW------FLNRFTTTLNDFNLVAMKYNYEPLTQDHVDIL 3513
D +T N++AWLYAA+I+ +L T +++D+N A + P + +
Sbjct 2974 DNLVTNNIVAWLYAAIISVKESSFSLPKWLESTTVSVDDYNKWAGDNGFTPFSTST--AI 3031
Query 3514 GPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVK 3573
LSA TG+ V + ++ + + G ILG EDE TP V Q GV QS+
Sbjct 3032 TKLSAITGVDVCKLLRTIM-VKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSFV 3090
Query 3574 RTIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 3630
R + W +L L L +V T L F++Y L A+ I+ + VK
Sbjct 3091 RKAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFT------VK 3143
Query 3631 HKHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRIMTWLDM--VDTSL------- 3674
H A++ FLLP+L TV A +Y + + V+ + W D DT +
Sbjct 3144 HVMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPL 3203
Query 3675 ---SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQA 3730
+ FK ++ C M + LL+L + ++T N LT + GN
Sbjct 3204 VLYTAFKCVQGCYMNSFNTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN----- 3251
Query 3731 ISMWALIISVTSNYSGVVTTVMFLARGIVFMC----VEYCPIFFITGNTLQCIMLVYCFL 3786
W L + + L VF C + YC ++ L +M+ +
Sbjct 3252 ---WELFFELVHTTVLANVSSNSLIGLFVFKCAKWMLYYCNATYLNNYVLMAVMVN--CI 3306
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G
Sbjct 3307 GWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQG 3366
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG + +ATVQ+K+SDVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E
Sbjct 3367 IGGDRVLPIATVQAKLSDVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGE 3426
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
+ ++ +L L + +D+++ C+++L LQ++ EFS +PSYA + A+ YE+
Sbjct 3427 CMDNLLGMLITLFCIDSTIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEK 3486
Query 3967 AVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKR 4022
+ + G ++ L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+R
Sbjct 3487 VLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRR 3546
Query 4023 AKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKN 4082
AK+ S++ +LF+ML+K+D++ LN + + A G VPL +P+ + KL +VIPD T+
Sbjct 3547 AKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVK 3606
Query 4083 TCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-----NSPNLAWPLIVTALRANSA- 4136
+G TY++ +W I V+DAD + + + N+AWPL V R
Sbjct 3607 CVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNK 3666
Query 4137 --VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
V LQNNEL P ++ +C AG Q C+ ++ YY G V A+ S +LK A
Sbjct 3667 VDVVLQNNELMPHGVKTKACVAGVDQAHCSVES-KCYYTNISGNSVVAAITSSNPNLKVA 3725
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
F G IY +L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+
Sbjct 3726 SFLNEAGN-QIYVDLDPPCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQS 3784
Query 4255 -GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
G+ TE +LS C+FAVD A Y Y+A+G QP+ NCVKML H G+G AIT P
Sbjct 3785 KGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPS 3844
Query 4314 ANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
DQ+S+GGAS CLYCR HI HP N G C KG +VQIPTT DPVGF L+N V
Sbjct 3845 PTPDQDSYGGASVCLYCRAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKV 3903
Query 4370 CTVCGMWKGYGCSCDQLREP--MLQSAD-----AQSFLN 4401
CTVC W GYGC CD LR+P +QS +++LN
Sbjct 3904 CTVCQCWIGYGCQCDSLRQPKSSVQSVAGASDFDKNYLN 3942
Score = 146 bits (368), Expect = 9e-33, Method: Composition-based stats.
Identities = 69/328 (21%), Positives = 119/328 (36%), Gaps = 29/328 (9%)
Query 925 YPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWL--DD 982
P + E+ Q E D A + EE +E L
Sbjct 909 EPVENSTGSSKTMTEQVVVEDQELPVVEQDQDVVVYTPTDLEVAKETAEEVDEFILIFAV 968
Query 983 DSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPV---VQTIEVNSFSGYLKLTDNVY 1039
++ V Q+DG++ Q + I V+PQ E + T E F Y ++
Sbjct 969 PKEEVVSQKDGAQIKQ----EPIQVVKPQREKKAKKFKVKPATCEKPKFLEYKTCVGDLT 1024
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKV 1099
+ A ++E K+ +VNAAN ++ HG GVA A+ +DY+ +GP +
Sbjct 1025 VVIAKALDEFKEF---CIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ- 1080
Query 1100 GGSCVLSGHNLAKHCL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGA 1156
V C+ +VVGP + L +AY+N V+ + P+LS GIFG
Sbjct 1081 --RLVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGV 1138
Query 1157 D---PIHSLRVCVDTVRTNVYLAVFDKNLYDKL------VSSFL--EMKSEKQVEQKIAE 1205
D I ++R + V L + D + +L + + + K +
Sbjct 1139 DFKMSIDAMREAFEGCTIRVLLFSLSQEHIDYFDVTCKQKTIYLTEDGVKYRSIVLKPGD 1198
Query 1206 IPKEEVKPFITESKPSVEQRKQDDKKIK 1233
+ + + +D + +
Sbjct 1199 SLGQFGQVYAKNKIVFTADDVEDKEILY 1226
Score = 45.4 bits (106), Expect = 0.031, Method: Composition-based stats.
Identities = 50/374 (13%), Positives = 111/374 (30%), Gaps = 20/374 (5%)
Query 524 GEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA 583
G I L A ++ V + + + + L + D ++L
Sbjct 374 GVTPEINDGLILAAIYSSFSVSELVTALKK--GEPFKFLGHKFVYAKDAAVSFTLAKAAT 431
Query 584 MMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLR 643
+ L + V+ + + + ++ +G V + V ++ + V
Sbjct 432 IADVLRLFQSARVIAEDVWSSFTEKSFEFWKLAYGKVRNLEEFVKTYVCKAQMSIVILAA 491
Query 644 DGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII-IGGAKLKA 702
E + + + +G + + F + + + ++ + G
Sbjct 492 VLGEDIWHLVSQVIYKLGVLFTKVVDFCDKHWKGFCVQLKRAKLIVTETFCVLKGVAQHC 551
Query 703 LNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGD 762
L + ++KC R LL +I+ +G+ + + + V G
Sbjct 552 FQLLLDAIHSLYKSFKKCALGRIHGDLLFWKGGVHKIVQ-DGDEIWFDAIDSVDVEDLGV 610
Query 763 LQPLEQPTSEAVEAPLV----GTPVCING-----LMLLEIKDTEKYCALAPNMMVTNNTF 813
+Q + L G V I + KD Y + N
Sbjct 611 VQEKSIDFEVCDDVTLPENQPGHMVQIEDDGKNYMFFRFKKDENIYYTPMSQLGAINVVC 670
Query 814 TLKGGAPTKVTFGDDTVIEV--QGYKSVNITFELD-ERIDKVLNEKCS-AYTVELGTEVN 869
VTFG+ TV E+ + ++ E E + + + V+ V
Sbjct 671 K---AGGKTVTFGETTVQEIPPPDVVPIKVSIECCGEPWNTIFKKAYKEPIEVDTDLTVE 727
Query 870 EFACVVADAVIKTL 883
+ V+ + + L
Sbjct 728 QLLSVIYEKMCDDL 741
>sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=1a PE=1 SV=1
Length=3951
Score = 2677 bits (6938), Expect = 0.0, Method: Composition-based stats.
Identities = 866/2979 (29%), Positives = 1372/2979 (46%), Gaps = 319/2979 (11%)
Query 1549 EVITFDNLKTLLSLREV--RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTK 1606
V+ F + + +V + ++ T D + + V+ + G QFG Y V
Sbjct 1157 RVLLFSLSQEHIDYFDVTCKQKTIYLTEDGVKYRSIVLKPGDSLG-QFGQVYAKNKIV-- 1213
Query 1607 IKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTS 1666
+ + + YV D ++ EYY D Y+ L +KW +
Sbjct 1214 FTADDVEDKEILYVPTTDKSI----LEYYG-LDAQKYVIYLQTL--AQKWNVQYRDNFLI 1266
Query 1667 IKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELG 1726
++W D NC++++A++ LQ +++F L +A+ + G+ +F A A C VG+
Sbjct 1267 LEWRDGNCWISSAIVLLQAAKIRFK-GFLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFS 1325
Query 1727 DVRETMSYLFQHANLDSCKRVLNV-VCKTCGQQQTTLKGVEAVM-YMGTLSYEQFKKGVQ 1784
D ++ L +H + D L V CG + L+G+EA + + + FK
Sbjct 1326 DANWLLANLAEHFDADYTNAFLKKRVSCNCGIKSYELRGLEACIQPVRATNLLHFKTQYS 1385
Query 1785 IPCTCGKQATKYLVQQESPFVMMSAP--PAQYELKHGTFTCASEYTGNYQCGH-YKHITS 1841
TCG T +++ P++++ A PA + + G+ GH Y
Sbjct 1386 NCPTCGANNTDEVIEASLPYLLLFATDGPATVDCDEDAVGT-VVFVGSTNSGHCYTQA-- 1442
Query 1842 KETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYK 1901
D + K P Y ++ K + + N
Sbjct 1443 --AGQAFDNLAKDRKFGKKSPYITAMYTRFAFKNETSLPVAKQSKGKSKSVKEDVSNL-- 1498
Query 1902 KDNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFP 1961
ASFDN D Q Y LKV P
Sbjct 1499 ----------------ATSSKASFDNL----------TDFEQW--YDSNIYESLKVQESP 1530
Query 1962 DLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVET 2021
D ++ Y T + + P T +R + S +
Sbjct 1531 D--------NFDKYVS------------------FTTKEDSKLPLTLKVRGIKSVVDFRS 1564
Query 2022 SNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVK---------TTEVV 2072
+ F + D PV V++ +++ +E N + +
Sbjct 1565 KDGFIYKLTPDTD------ENSKAPVYYPVLDAISLKAIWVEGNANFVVGHPNYYSKSLH 1618
Query 2073 GDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNS 2132
+ A N +K+ +++G + ++ + KPN L R+ + A G + V +
Sbjct 1619 IPTFWENAENFVKMGDKIGGVTMGLWRAEH----LNKPN-LERIFNIAKKAIVGSSVVTT 1673
Query 2133 VPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVC--------TNYMPYFF-TLLLQLCTFT 2183
I A +KV +T + +C P F TL+ L F
Sbjct 1674 QCGKLIGKAATFIADKVGGGVVRNITDSIKGLCGITRGHFERKMSPQFLKTLMFFLFYFL 1733
Query 2184 RSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSL 2243
+++ + AS T + K + ++ +I+WF+ S +
Sbjct 1734 KASVKSVVASYKTVLCKVVLATL----------------------LIVWFVYTS---NPV 1768
Query 2244 IYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPS 2303
+++ + + L S C Y++ +S + YC C VCL DSL Y
Sbjct 1769 MFTGIRV---LDFLFEGSLCGPYKDYGKDS--FDVLRYCADDFICRVCLHDKDSLHLYKH 1823
Query 2304 LETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAIMQLFFSYFAVHFISN 2361
+++ A G + W Y++F F V G I Y + + N
Sbjct 1824 AYSVEQVYKD-----AASGFIFNWNWLYLVFLILFVKPVAGFVII-----CYCVKYLVLN 1873
Query 2362 SWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVVDGCNSSTCMMCYKRN 2416
S ++ + + + + + F + +Y W Y VH + C TC +C +
Sbjct 1874 STVLQTGVCFLDWF-VQTVFSHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVA 1932
Query 2417 RATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQ 2476
R+ R E + +V G ++ +VY N G FCK HNW C NCD + +TF+S EVA +LS +
Sbjct 1933 RSNRQEVSVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEK 1992
Query 2477 FKRPINPTDQSSYIVDSVTVKNGSIHLYFDK-AGQKTYERHSLSHFVNLDNLR-ANNTKG 2534
KR + PT + ++VD + + ++L + K ++ F D L+ A K
Sbjct 1993 LKRHVKPTAYAYHVVDEACLVDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKE 2052
Query 2535 SLPINVIVFDGKSKCEESSA------KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAV 2588
+L I DG C SA K+A++YY+Q +C+PIL+LDQAL +
Sbjct 2053 ALKCEQISNDGFIVCNTQSAHALEEAKNAAIYYAQYLCKPILILDQALYEQL-------- 2104
Query 2589 KMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVET 2648
V K+++ + L+ +S+D + + + + S +
Sbjct 2105 ---------------VVEPVSKSVIDKVCSILSSIISVDTAALNYKAGTLRDALLSITKD 2149
Query 2649 KDVVECLKLSHQSDIEVTGDSCNNYMLTY-NKVENMTPRDLGACIDCSARHINAQVAKSH 2707
++ V+ H D++ TGD N + +Y +TPRD G I+ A N +V +
Sbjct 2150 EEAVDMAIFCHNHDVDYTGDGFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAP 2209
Query 2708 NIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL--KGGKI 2765
++W + + LS+ K + SA K+ + F +T + +QV+ T K+ + K G I
Sbjct 2210 --PVVWKFSELIKLSDSCLKYLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGI 2267
Query 2766 VNN---WLKQLIKVTLVFLF-----VAAIFYLITPVHVMSKHTDFSS--EIIGYKAIDGG 2815
V+ K K L+F + +Y+ + D +S + G+K ID G
Sbjct 2268 VSGTFKCFKSYFKWLLIFYILFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKG 2327
Query 2816 VTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILR 2875
V R+I DTCF+NK +FD ++ G Y N + CP++ AVI + G V G+PG +
Sbjct 2328 VLREIVPEDTCFSNKFVNFDAFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSW 2383
Query 2876 TTNG-DFLH---------FLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDA 2925
+G F+H ++P F+ + YT +I F TS + +A C ++ A
Sbjct 2384 VMDGVMFIHMTQTERKPWYIPTWFNRE-IVGYTQDSIITEGSFYTSIALFSARC-LYLTA 2441
Query 2926 SGKPVPYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYC 2984
S P YC++ N G++ + S+ P Y +G + P L V DS YC
Sbjct 2442 SNTPQLYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQILHTPYVVKFVSDS-YC 2500
Query 2985 RHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDIS 3044
R CE + G CVS + +WVL ND Y S PGVFCG L+ +M + + +I
Sbjct 2501 RGSVCEYTRPGYCVSLNPQWVLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIY 2559
Query 3045 ASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGV 3104
+ ++ +VV + ++F+ F Y+ V L+++++ +LC+ S L +
Sbjct 2560 MQLATMFLILVVVVLIFAMVIKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVI 2619
Query 3105 YSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAY---IICISTKHFYWFFSNYL 3161
V+Y Y + + + + H + F +VP W+ Y II + T F W +
Sbjct 2620 LLVLYCYASLVTSRNTVIIMHCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTK 2679
Query 3162 KRRVVFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGA 3220
R +++G F ++ AA TF++ ++KL +++ ++ YL+ Y + KY+SG
Sbjct 2680 NTRKLYDGNEFVGNYDLAAKSTFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGT 2736
Query 3221 MDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCM 3280
Y +A LA AL+ + NSG +++Y PP+ SI + LQSGF+K+ PS VE C+
Sbjct 2737 GSEQDYLQACRAWLAYALDQYRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCI 2796
Query 3281 VQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGN-VQLR 3339
V V+ LNGLWL D +YCPRHV+ + D+L +NH F V + V L
Sbjct 2797 VSVSYRGNNLNGLWLGDTIYCPRHVL---GKFSGDQWNDVLNLANNHEFEVTTQHGVTLN 2853
Query 3340 VIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTI 3399
V+ ++ VL L+ AN +TPKYKF++ G +F++ Y G+ G+Y MR N TI
Sbjct 2854 VVSRRLKGAVLILQTAVANAETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTI 2913
Query 3400 KGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGT 3459
+ SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G FYG +VD + AQ
Sbjct 2914 RASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPP 2973
Query 3460 DTTITVNVLAWLYAAVINGDRW------FLNRFTTTLNDFNLVAMKYNYEPLTQDHVDIL 3513
D +T N++AWLYAA+I+ +L T +++D+N A + P + +
Sbjct 2974 DNLVTNNIVAWLYAAIISVKESSFSLPKWLESTTVSVDDYNKWAGDNGFTPFSTST--AI 3031
Query 3514 GPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVK 3573
LSA TG+ V + ++ + + G ILG EDE TP V Q GV QS+
Sbjct 3032 TKLSAITGVDVCKLLRTIM-VKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSFV 3090
Query 3574 RTIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 3630
R + W +L L L +V T L F++Y L A+ I+ + VK
Sbjct 3091 RKAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVYAAVILLMAVLFISFT------VK 3143
Query 3631 HKHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRIMTWLDM--VDTSL------- 3674
H A++ FLLP+L TV A +Y + + V+ + W D DT +
Sbjct 3144 HVMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMFLPL 3203
Query 3675 ---SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQA 3730
+ FK ++ C M + LL+L + ++T N LT + GN
Sbjct 3204 VLYTAFKCVQGCYMNSFNTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN----- 3251
Query 3731 ISMWALIISVTSNYSGVVTTVMFLARGIVFMC----VEYCPIFFITGNTLQCIMLVYCFL 3786
W L + + L VF C + YC ++ L +M+ +
Sbjct 3252 ---WELFFELVHTTVLANVSSNSLIGLFVFKCAKWMLYYCNATYLNNYVLMAVMVN--CI 3306
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G
Sbjct 3307 GWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQG 3366
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG + +ATVQ+K+SDVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E
Sbjct 3367 IGGDRVLPIATVQAKLSDVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGE 3426
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
+ ++ +L L + +D+++ C+++L LQ++ EFS +PSYA + A+ YE+
Sbjct 3427 CMDNLLGMLITLFCIDSTIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEK 3486
Query 3967 AVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKR 4022
+ + G ++ L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+R
Sbjct 3487 VLVDSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRR 3546
Query 4023 AKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKN 4082
AK+ S++ +LF+ML+K+D++ LN + + A G VPL +P+ + KL +VIPD T+
Sbjct 3547 AKLVSSLHALLFSMLKKIDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVK 3606
Query 4083 TCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-----NSPNLAWPLIVTALRANSA- 4136
+G TY++ +W I V+DAD + + + N+AWPL V R
Sbjct 3607 CVEGVHVTYSTVVWNIDTVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNK 3666
Query 4137 --VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
V LQNNEL P ++ +C AG Q C+ ++ YY G V A+ S +LK A
Sbjct 3667 VDVVLQNNELMPHGVKTKACVAGVDQAHCSVES-KCYYTNISGNSVVAAITSSNPNLKVA 3725
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
F G IY +L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+
Sbjct 3726 SFLNEAGN-QIYVDLDPPCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQS 3784
Query 4255 -GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
G+ TE +LS C+FAVD A Y Y+A+G QP+ NCVKML H G+G AIT P
Sbjct 3785 KGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPS 3844
Query 4314 ANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
DQ+S+GGAS CLYCR HI HP N G C KG +VQIPTT DPVGF L+N V
Sbjct 3845 PTPDQDSYGGASVCLYCRAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKV 3903
Query 4370 CTVCGMWKGYGCSCDQLREP--MLQSAD-----AQSFLN 4401
CTVC W GYGC CD LR+P +QS +++LN
Sbjct 3904 CTVCQCWIGYGCQCDSLRQPKSSVQSVAGASDFDKNYLN 3942
Score = 146 bits (368), Expect = 9e-33, Method: Composition-based stats.
Identities = 69/328 (21%), Positives = 119/328 (36%), Gaps = 29/328 (9%)
Query 925 YPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWL--DD 982
P + E+ Q E D A + EE +E L
Sbjct 909 EPVENSTGSSKTMTEQVVVEDQELPVVEQDQDVVVYTPTDLEVAKETAEEVDEFILIFAV 968
Query 983 DSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPV---VQTIEVNSFSGYLKLTDNVY 1039
++ V Q+DG++ Q + I V+PQ E + T E F Y ++
Sbjct 969 PKEEVVSQKDGAQIKQ----EPIQVVKPQREKKAKKFKVKPATCEKPKFLEYKTCVGDLT 1024
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKV 1099
+ A ++E K+ +VNAAN ++ HG GVA A+ +DY+ +GP +
Sbjct 1025 VVIAKALDEFKEF---CIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ- 1080
Query 1100 GGSCVLSGHNLAKHCL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGA 1156
V C+ +VVGP + L +AY+N V+ + P+LS GIFG
Sbjct 1081 --RLVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGV 1138
Query 1157 D---PIHSLRVCVDTVRTNVYLAVFDKNLYDKL------VSSFL--EMKSEKQVEQKIAE 1205
D I ++R + V L + D + +L + + + K +
Sbjct 1139 DFKMSIDAMREAFEGCTIRVLLFSLSQEHIDYFDVTCKQKTIYLTEDGVKYRSIVLKPGD 1198
Query 1206 IPKEEVKPFITESKPSVEQRKQDDKKIK 1233
+ + + +D + +
Sbjct 1199 SLGQFGQVYAKNKIVFTADDVEDKEILY 1226
Score = 45.4 bits (106), Expect = 0.031, Method: Composition-based stats.
Identities = 50/374 (13%), Positives = 111/374 (30%), Gaps = 20/374 (5%)
Query 524 GEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA 583
G I L A ++ V + + + + L + D ++L
Sbjct 374 GVTPEINDGLILAAIYSSFSVSELVTALKK--GEPFKFLGHKFVYAKDAAVSFTLAKAAT 431
Query 584 MMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLR 643
+ L + V+ + + + ++ +G V + V ++ + V
Sbjct 432 IADVLRLFQSARVIAEDVWSSFTEKSFEFWKLAYGKVRNLEEFVKTYVCKAQMSIVILAA 491
Query 644 DGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII-IGGAKLKA 702
E + + + +G + + F + + + ++ + G
Sbjct 492 VLGEDIWHLVSQVIYKLGVLFTKVVDFCDKHWKGFCVQLKRAKLIVTETFCVLKGVAQHC 551
Query 703 LNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGD 762
L + ++KC R LL +I+ +G+ + + + V G
Sbjct 552 FQLLLDAIHSLYKSFKKCALGRIHGDLLFWKGGVHKIVQ-DGDEIWFDAIDSVDVEDLGV 610
Query 763 LQPLEQPTSEAVEAPLV----GTPVCING-----LMLLEIKDTEKYCALAPNMMVTNNTF 813
+Q + L G V I + KD Y + N
Sbjct 611 VQEKSIDFEVCDDVTLPENQPGHMVQIEDDGKNYMFFRFKKDENIYYTPMSQLGAINVVC 670
Query 814 TLKGGAPTKVTFGDDTVIEV--QGYKSVNITFELD-ERIDKVLNEKCS-AYTVELGTEVN 869
VTFG+ TV E+ + ++ E E + + + V+ V
Sbjct 671 K---AGGKTVTFGETTVQEIPPPDVVPIKVSIECCGEPWNTIFKKAYKEPIEVDTDLTVE 727
Query 870 EFACVVADAVIKTL 883
+ V+ + + L
Sbjct 728 QLLSVIYEKMCDDL 741
>sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=1a PE=1 SV=1
Length=3953
Score = 2655 bits (6882), Expect = 0.0, Method: Composition-based stats.
Identities = 860/2979 (29%), Positives = 1369/2979 (46%), Gaps = 319/2979 (11%)
Query 1549 EVITFDNLKTLLSLREV--RTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTK 1606
V+ F + + + + ++ T D + + V+ + G QFG + V
Sbjct 1159 RVLLFSLSQEHIDYFDATCKQKTIYLTEDGVKYRSVVLKPGDSLG-QFGQVFARNKVV-- 1215
Query 1607 IKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTS 1666
+ E K +P D +E Y+ D Y+ L +KW +
Sbjct 1216 -FSADDVEDKEILFIPTTDKTILE----YYGLDAQKYVTYLQTL--AQKWDVQYRDNFVI 1268
Query 1667 IKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELG 1726
++W D NC++++A++ LQ +++F L +A+ + G+ +F A A CN VG+
Sbjct 1269 LEWRDGNCWISSAIVLLQAAKIRFK-GFLAEAWAKLLGGDPTDFVAWCYASCNAKVGDFS 1327
Query 1727 DVRETMSYLFQHANLDSCKRVLN-VVCKTCGQQQTTLKGVEAVM-YMGTLSYEQFKKGVQ 1784
D ++ L +H + D +L V CG + L+G+EA + + + FK
Sbjct 1328 DANWLLANLAEHFDADYTNALLKKCVSCNCGVKSYELRGLEACIQPVRAPNLLHFKTQYS 1387
Query 1785 IPCTCGKQATKYLVQQESPFVMMSAPPAQYELK-HGTFTCASEYTGNYQCGH-YKHITSK 1842
TCG +T +++ P++++ A + + G+ GH Y K
Sbjct 1388 NCPTCGASSTDEVIEASLPYLLLFATDGPATVDCDENAVGTVVFIGSTNSGHCYTQADGK 1447
Query 1843 ETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKK 1902
D + K P Y S + + + + + N
Sbjct 1448 A----FDNLAKDRKFGRKSPYITAMYTRFSLRSENPLLVVEHSKGKAKVVKEDVSNL--- 1500
Query 1903 DNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPD 1962
ASFD+ D Q Y LKV PD
Sbjct 1501 ---------------ATSSKASFDDL----------TDFEQW--YDSNIYESLKVQETPD 1533
Query 1963 LNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETS 2022
+ Y T + + P T +R + S +
Sbjct 1534 --------NLDEYVS------------------FTTKEDSKLPLTLKVRGIKSVVDFRSK 1567
Query 2023 NSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVK---------TTEVVG 2073
+ F + D PV V+++ +++ +E + + +
Sbjct 1568 DGFTYKLTPDTD------ENSKTPVYYPVLDSISLRAIWVEGSANFVVGHPNYYSKSLRI 1621
Query 2074 DIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSV 2133
+ A + +K+ ++ + ++ + KPN L R+ + A G + V +
Sbjct 1622 PTFWENAESFVKMGYKIDGVTMGLWRAEH----LNKPN-LERIFNIAKKAIVGSSVVTTQ 1676
Query 2134 PWDTIANYAKPFLNKVVSTTTNIVTRCLNRVC---------TNYMPYFFTLLLQLCTFTR 2184
+ A +KV +T + +C + + TL+ F +
Sbjct 1677 CGKILVKAATYVADKVGDGVVRNITDRIKGLCGFTRGHFEKKMSLQFLKTLVFFFFYFLK 1736
Query 2185 STNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLI 2244
+++ + +S + K ++ +I+WF+ S ++
Sbjct 1737 ASSKSLVSSYKIVLCKVVFATL----------------------LIVWFIYTS---NPVV 1771
Query 2245 YSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSL 2304
++ + + L S C Y + +S + YC G C VCL DSL Y
Sbjct 1772 FTGIRV---LDFLFEGSLCGPYNDYGKDS--FDVLRYCAGDFTCRVCLHDRDSLHLYKHA 1826
Query 2305 ETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFY--VLGLAAIMQLFFSYFAVHFISNS 2362
+++ A G+ W Y++F F V G I Y + + +S
Sbjct 1827 YSVEQIYKD-----AASGINFNWNWLYLVFLILFVKPVAGFVII-----CYCVKYLVLSS 1876
Query 2363 WLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY-----VHVVDGCNSSTCMMCYKRNR 2417
++ + + + + + F + +Y W Y VH + C TC +C + R
Sbjct 1877 TVLQTGVGFLDWF-VKTVFTHFNFMGAGFYFWLFYKIYVQVHHILYCKDVTCEVCKRVAR 1935
Query 2418 ATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQF 2477
+ R E + +V G ++ +VY N G FCK HNW C NCD + +TF+S EVA +LS +
Sbjct 1936 SNRQEVSVVVGGRKQIVHVYTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKL 1995
Query 2478 KRPINPTDQSSYIVDSVTVKNGSIHLYFDKA-GQKTYERHSLSHFVNLDNLR-ANNTKGS 2535
KR + PT + ++V V + ++L + A K ++ F D L+ A K +
Sbjct 1996 KRHVKPTAYAYHVVYEACVVDDFVNLKYKAAIPGKDNASSAVKCFSVTDFLKKAVFLKEA 2055
Query 2536 LPINVIVFDGKSKCEESSA------KSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVK 2589
L I DG C SA K+A+VYY+Q +C+PIL+LDQAL +
Sbjct 2056 LKCEQISNDGFIVCNTQSAHALEEAKNAAVYYAQYLCKPILILDQALYEQL--------- 2106
Query 2590 MFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETK 2649
+ K+++ + L+ +S+D + + + + S + +
Sbjct 2107 --------------IVEPVSKSVIDKVCSILSNIISVDTAALNYKAGTLRDALLSITKDE 2152
Query 2650 DVVECLKLSHQSDIEVTGDSCNNYMLTYN-KVENMTPRDLGACIDCSARHINAQVAKSHN 2708
+ V+ H ++E TGD N + +Y + +TPRD G I+ A N +V +
Sbjct 2153 EAVDMAIFCHNHEVEYTGDGFTNVIPSYGMDTDKLTPRDRGFLINADASIANLRVKNAP- 2211
Query 2709 IALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIAL--KGGKIV 2766
++W D + LS+ K + SA K+ F +T + +QV++ T K+ + K G ++
Sbjct 2212 -PVVWKFSDLIKLSDSCLKYLISATVKSGGRFFITKSGAKQVISCHTQKLLVEKKAGGVI 2270
Query 2767 NN---WLKQLIKVTLVFLF-----VAAIFYLITPVHVMSKHTDFSS--EIIGYKAIDGGV 2816
NN W K VF +Y+ + D +S + G+K ID GV
Sbjct 2271 NNTFKWFMSCFKWLFVFYILFTACCLGYYYMEMNKSFVHPMYDVNSTLHVEGFKVIDKGV 2330
Query 2817 TRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRT 2876
R+I S D CF+NK +FD ++ G SY N+K CP++ VI + G V G+PG +
Sbjct 2331 IREIVSEDNCFSNKFVNFDAFW---GKSYENNKNCPIVTVVIDGD-GTVAVGVPGFVSWV 2386
Query 2877 TNG-DFLH---------FLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDAS 2926
+G F+H ++P F+ + YT +I F TS + +A C ++ AS
Sbjct 2387 MDGVMFVHMTQTDRRPWYIPTWFNRE-IVGYTQDSIITEGSFYTSIALFSARC-LYLTAS 2444
Query 2927 GKPVPYCYD-TNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCR 2985
P YC++ N G++ + S+ P Y +G + P L V DS YCR
Sbjct 2445 NTPQLYCFNGDNDAPGALPFGSIIPHRVYFQPNGVRLIVPQQILHTPYIVKFVSDS-YCR 2503
Query 2986 HGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISA 3045
CE ++ G CVS +WVL ND Y S PGVFCG L+ NM + + +I
Sbjct 2504 GSVCEYTKPGYCVSLDSQWVLFNDEYISKPGVFCGSTVRELMFNMVSTFFTGVNP-NIYI 2562
Query 3046 SIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVY 3105
+ ++ +V+ + ++F+ F Y+ +V L+++++ VLC+ S L +
Sbjct 2563 QLATMFLILVVIVLIFAMVIKFQGVFKAYATIVFTIMLVWVINAFVLCVHSYNSVLAVIL 2622
Query 3106 SVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAY---IICISTKHFYWFFSNYLK 3162
V+Y Y + + + + + H + F +VP W+ Y I+ + T +W +
Sbjct 2623 LVLYCYASMVTSRNTAIIMHCWLVFTFGLIVPTWLACCYLGFILYMYTPLVFWCYGTTKN 2682
Query 3163 RRVVFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAM 3221
R +++G F ++ AA TF++ ++KL +++ ++ YL+ Y + KY+SG
Sbjct 2683 TRKLYDGNEFVGNYDLAAKSTFVIRGTEFVKLTNEIG---DKFEAYLSAYARLKYYSGTG 2739
Query 3222 DTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMV 3281
Y +A LA AL+ + NSG +V+Y PP+ SI + LQ+GF+K+ PS VE C+V
Sbjct 2740 SEQDYLQACRAWLAYALDQYRNSGVEVVYTPPRYSIGVSRLQAGFKKLVSPSSAVEKCIV 2799
Query 3282 QVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGN-VQLRV 3340
V+ LNGLWL D +YCPRHV+ + D+L +NH F V N V L V
Sbjct 2800 SVSYRGNNLNGLWLGDSIYCPRHVL---GKFSGDQWGDVLNLANNHEFEVVTQNGVTLNV 2856
Query 3341 IGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIK 3400
+ ++ VL L+ AN +TPKYKFV+ G +F++ Y G+ G+Y MR N TI+
Sbjct 2857 VSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIR 2916
Query 3401 GSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTD 3460
SFL G+CGSVGFNI+ V+F YMHH+ELP +H GTDL G FYG +VD + AQ D
Sbjct 2917 ASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPD 2976
Query 3461 TTITVNVLAWLYAAVIN-------GDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDIL 3513
+T N++AWLYAA+I+ +W L T ++ D+N A + P + +
Sbjct 2977 NLVTNNIVAWLYAAIISVKESSFSQPKW-LESTTVSIEDYNRWASDNGFTPFSTST--AI 3033
Query 3514 GPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVK 3573
LSA TG+ V + ++ + ILG EDE TP V Q GV QS+
Sbjct 3034 TKLSAITGVDVCKLLRTIM-VKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQSSFV 3092
Query 3574 RTIKGTHHW---LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVK 3630
R + W +L L L +V T L F+++ L A+ I+ + VK
Sbjct 3093 RKAT-SWFWSRCVLACFLFVLCAIVLFTAVPLKFYVHAAVILLMAVLFISFT------VK 3145
Query 3631 HKHAFLCLFLLPSLATV-----AYFNMVY--MPASWVMRIMTWLDM--VDTSL------- 3674
H A++ FLLP+L TV A +Y + + V+ + W D DT +
Sbjct 3146 HVMAYMDTFLLPTLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMLLPL 3205
Query 3675 ---SGFK-LKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQA 3730
+ FK ++ C M + LL+L ++T N LT + GN
Sbjct 3206 VLYTAFKCVQGCYMNSFNTSLLMLYQFM----KLGFVIYTSSNTLTAYTE---GN----- 3253
Query 3731 ISMWALIISVTSNYSGVVTTVMFLARGIVFMC----VEYCPIFFITGNTLQCIMLVYCFL 3786
W L + + L IVF C + YC + L +M+ +
Sbjct 3254 ---WELFFELVHTIVLANVSSNSLIGLIVFKCAKWMLYYCNATYFNNYVLMAVMVN--GI 3308
Query 3787 GYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLG 3846
G+ CTCYFGL+ +N+ F LTLG Y++ VS ++RYM + PPK + F NI + G
Sbjct 3309 GWLCTCYFGLYWWVNKVFGLTLGKYNFKVSVDQYRYMCLHKVNPPKTVWEVFTTNILIQG 3368
Query 3847 VGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTE 3906
+GG + +ATVQSK+SDVKCT+VVL+ +L +L VE++SK+ A V+LHN IL + D E
Sbjct 3369 IGGDRVLPIATVQSKLSDVKCTTVVLMQLLTKLNVEANSKMHAYLVELHNKILASDDVGE 3428
Query 3907 AFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQ 3966
+ ++ +L L + +D+ + C+++L LQ++ EFS +PSYA + A+ YE+
Sbjct 3429 CMDNLLGMLITLFCIDSTIDLGEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKSIYEK 3488
Query 3967 AVAN----GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKR 4022
+A+ G ++ L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+R
Sbjct 3489 VLADSKNGGVTQQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRR 3548
Query 4023 AKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKN 4082
AK+ S++ +LF+ML+K+D++ LN + + A G VPL +P+ + KL +VIPD T+
Sbjct 3549 AKLVSSLHALLFSMLKKIDSEKLNVLFDQANSGVVPLATVPIVCSNKLTLVIPDPETWVK 3608
Query 4083 TCDGTTFTYASALWEIQQVVDADSKIVQLSEISMD-----NSPNLAWPLIVTALRANSA- 4136
+G TY++ +W I V DAD + + + N+AWPL V R
Sbjct 3609 CVEGVHVTYSTVVWNIDCVTDADGTELHPTSTGSGLTYCISGDNIAWPLKVNLTRNGHNK 3668
Query 4137 --VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWA 4194
V LQNNEL P ++ +C AG Q C+ ++ YY + G V A+ S +LK A
Sbjct 3669 VDVALQNNELMPHGVKTKACVAGVDQAHCSVES-KCYYTSISGSSVVAAITSSNPNLKVA 3727
Query 4195 RFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA 4254
F G IY +L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+
Sbjct 3728 SFLNEAGN-QIYVDLDPPCKFGMKVGDKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQS 3786
Query 4255 -GNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
G+ TE +LS C+FAVD A Y Y+A+G QP+ NCVKML H G+G AIT P
Sbjct 3787 KGHETEEVDAVGILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPS 3846
Query 4314 ANMDQESFGGASCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLKNTV 4369
DQ+S+GGAS CLYCR HI HP N G C KG +VQIPTT DPVGF L+N V
Sbjct 3847 PTPDQDSYGGASVCLYCRAHIAHPGGAGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKV 3905
Query 4370 CTVCGMWKGYGCSCDQLREP-------MLQSADAQSFLN 4401
CTVC W GYGC CD LR+P + S +++LN
Sbjct 3906 CTVCQCWIGYGCQCDSLRQPKPSVQSVAVASGFDKNYLN 3944
Score = 147 bits (371), Expect = 4e-33, Method: Composition-based stats.
Identities = 60/315 (19%), Positives = 112/315 (36%), Gaps = 23/315 (7%)
Query 933 EGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQD 992
D E+ Q + Q + A ++ E+ ++++ +
Sbjct 917 SCDAMAEQAIVEEQEIVPVVEQSQDVVVFTPADLEVVKETAEEVDEFILISAVPKEEVVS 976
Query 993 GSEDNQTTTIQTIVEVQPQLEMELTPV---VQTIEVNSFSGYLKLTDNVYIKNADIVEEA 1049
++ + + V+ Q E + T E F Y ++ + A ++E
Sbjct 977 QEKEEPQVEQEPTLVVKAQREKKAKKFKVKPATCEKPKFLEYKTCVGDLAVVIAKALDEF 1036
Query 1050 KKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHN 1109
K+ +VNAAN ++ HGGGVA A+ DY+ +GP + V
Sbjct 1037 KEF---CIVNAANEHMSHGGGVAKAIADFCGPDFVEYCADYVKKHGPQQ---KLVTPSFV 1090
Query 1110 LAKHCL-HVVGPNVNKGEDIQLLKSAYENFNQHEVL--LAPLLSAGIFGAD---PIHSLR 1163
C+ +VVGP + L +AY++ V+ + P+LS+GIFG D I ++R
Sbjct 1091 KGIQCVNNVVGPRHGDSNLREKLVAAYKSVLVGGVVNYVVPVLSSGIFGVDFKISIDAMR 1150
Query 1164 VCVDTVRTNVYLAVFDKNLYDKL------VSSFL--EMKSEKQVEQKIAEIPKEEVKPFI 1215
V L + D + +L + + V K + + + F
Sbjct 1151 EAFKGCAIRVLLFSLSQEHIDYFDATCKQKTIYLTEDGVKYRSVVLKPGDSLGQFGQVFA 1210
Query 1216 TESKPSVEQRKQDDK 1230
+D +
Sbjct 1211 RNKVVFSADDVEDKE 1225
Score = 51.6 bits (122), Expect = 4e-04, Method: Composition-based stats.
Identities = 57/375 (15%), Positives = 113/375 (30%), Gaps = 22/375 (6%)
Query 524 GEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDA 583
G I L A ++ V + + + L + D ++L
Sbjct 374 GVTPEINDGLILAAIYSSFSVAELVAAIKR--GEPFKFLGHKFVYAKDAAVSFTLAKAAT 431
Query 584 MMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFK-EGVEFL 642
+ L + V + + + + + ++ +G V L+ + K + V
Sbjct 432 IADVLKLFQSARVKVEDVWSSLTEKSFEFWRLAYGKVRN-LEEFVKTCFCKAQMAIVILA 490
Query 643 RDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSII-IGGAKLK 701
E + + + VGG ++ + F + + + +++ + G
Sbjct 491 TVLGEGIWHLVSQVIYKVGGLFTKVVDFCEKYWKGFCAQLKRAKLIVTETLCVLKGVAQH 550
Query 702 ALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTG 761
L + ++KC R LL +II EG+ + + + V G
Sbjct 551 CFQLLLDAIQFMYKSFKKCALGRIHGDLLFWKGGVHKIIQ-EGDEIWFDAIDSIDVEDLG 609
Query 762 DLQPLEQPTSEAVEAPLV----GTPVCING-----LMLLEIKDTEKYCALAPNMMVTNNT 812
+Q L G V I + KD Y + N
Sbjct 610 VVQEKLIDFDVCDNVTLPENQPGHMVQIEDDGKNYMFFRFKKDENIYYTPMSQLGAINVV 669
Query 813 FTLKGGAPTKVTFGDDTVIEV--QGYKSVNITFELD-ERIDKVLNEKCS-AYTVELGTEV 868
VTFG+ TV E+ + ++ E E + + + VE V
Sbjct 670 CK---AGGKTVTFGETTVQEIPPPDVVFIKVSIECCGEPWNTIFKKAYKEPIEVETDLTV 726
Query 869 NEFACVVADAVIKTL 883
+ VV + + L
Sbjct 727 EQLLSVVYEKMCDDL 741
>sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus
229E OX=11137 GN=1a PE=1 SV=1
Length=4085
Score = 2602 bits (6744), Expect = 0.0, Method: Composition-based stats.
Identities = 753/2308 (33%), Positives = 1185/2308 (51%), Gaps = 137/2308 (6%)
Query 2124 THGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVC-------TNYMPYFFTLL 2176
H L+ ++ + Y P N + + N++ FFT L
Sbjct 1882 KHDLSLLSVTSVVMVGGYVAPVNTVKPKPVINQLDEKAQKFFDFGDFLIHNFV-IFFTWL 1940
Query 2177 LQLCTFTRST----NSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIW 2232
L + T ++ + +I A P +S+ K+ L+AS LKS W
Sbjct 1941 LSMFTLCKTAVTTGDVKIMAKAPQRTGVVLKRSL-KYNLKASAAVLKSK----------W 1989
Query 2233 FLLLSVC-LGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVC 2291
+LL L LIY+ ++ +L G ++C+ GY S N YC GS+ C +C
Sbjct 1990 WLLAKFTKLLLLIYTLYSVVLLCVRFGPFNFCSETVNGYAKS-NFVKDDYCDGSLGCKMC 2048
Query 2292 LSGLDSLDTYPSLETIQITISSFKW-DLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLF 2350
L G L + L+ + I+ + ++ F ++ + + R F + +A ++
Sbjct 2049 LFGYQELSQFSHLDVVWKHITDPLFSNMQPFIVMVLLLIFGDNYLRCFLLYFVAQMISTV 2108
Query 2351 FSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCM 2410
+ + +W + P + + V HV+ GC + C+
Sbjct 2109 GVFLG--YKETNWFLHF-------IPFDVICDELLVTVIVIKVISFVRHVLFGCENPDCI 2159
Query 2411 MCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVA 2470
C K R R TIVNGV+RSFYV ANGG FCK H + CV+CD++ GSTFI+ EV+
Sbjct 2160 ACSKSARLKRFPVNTIVNGVQRSFYVNANGGSKFCKKHRFFCVDCDSYGYGSTFITPEVS 2219
Query 2471 RDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRAN 2530
R+L K + PT + ++D V +NG LY + + + S + + +
Sbjct 2220 RELGNITKTNVQPTGPAYVMIDKVEFENGFYRLYSCETFWRYNFDITESKYSCKEVFKNC 2279
Query 2531 NTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKM 2590
N + IVF+ + K+ASVY+SQL+C+PI L+D L+S + S + +
Sbjct 2280 NV----LDDFIVFNNNGT-NVTQVKNASVYFSQLLCRPIKLVDSELLSTL--SVDFNGVL 2332
Query 2591 FDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKD 2650
AY++ ++F L ++ AE + A +S+ +
Sbjct 2333 HKAYIDVLRNSFGKD---LNANMSLAECKRALGLSI--------------------SDHE 2369
Query 2651 VVECLKLSHQSDIEVTGDSCNNYMLTYNKVE-NMTPRDLGACIDCSARHINAQVAKSHNI 2709
+ +H+ D+ ++ S NN++ +Y K E ++ DL C+ A+ +NA V
Sbjct 2370 FTSAISNAHRCDVLLSDLSFNNFVSSYAKPEEKLSAYDLACCMRAGAKVVNANVLTKDQT 2429
Query 2710 ALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNN- 2768
++W+ KDF SLS + RK I +K L F LT + V + T I K G
Sbjct 2430 PIVWHAKDFNSLSAEGRKYIVKTSKAKGLTFLLTINENQAVTQIPATSIVAKQGAGDAGH 2489
Query 2769 ---WLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDT 2825
WL L + + F F ++S S E +K I+ G ++ +
Sbjct 2490 SLTWLWLLCGLVCLIQFYLCFFMPYFMYDIVS-----SFEGYDFKYIENGQLKNFEAPLK 2544
Query 2826 CFANKHADFDTWFSQRGGS-YTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHF 2884
C N +F+ W + G N ++CP++ V E+ V G+P + G L F
Sbjct 2545 CVRNVFENFEDWHYAKFGFTPLNKQSCPIVVGV--SEIVNTVAGIPSNVYLV--GKTLIF 2600
Query 2885 LPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVA 2944
+ +CY + C+ + CT + G V YCY+T ++EGS+
Sbjct 2601 TLQAAFGNAGVCYD-----IFGVTTPEKCIFTSACTRLEGLGGNNV-YCYNTALMEGSLP 2654
Query 2945 YESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCERSEAGVCVSTSGR 3003
Y S++ + Y +G+ I+ P +G R V T ++YCR G C S AGVC +
Sbjct 2655 YSSIQANAYYKYDNGNFIKLPEVIAQGFGFRTVRTIATKYCRVGECVESNAGVCFGFD-K 2713
Query 3004 WVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYY 3063
W +N+ R G CG NL+ N+ + +S I+ + +
Sbjct 2714 WFVNDG--RVANGYVCGTGLWNLVFNILSMFSSSFSVAAMSGQILLNCALGAFAIFCCFL 2771
Query 3064 FMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFL 3123
+FRR FG+ S V + L++ +T + Y+++Y + T L +++
Sbjct 2772 VTKFRRMFGDLSVGVCTVVVAVLLNNVSYIVTQNLVTMIA-YAILYFFATRSL--RYAWI 2828
Query 3124 AHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFNGVSF-STFEEAA 3179
+++ + P+W+ Y + + T + LK +V +F G F TFE AA
Sbjct 2829 WCAAYLIAYISFAPWWLCAWYFLAMLTG----LLPSLLKLKVSTNLFEGDKFVGTFESAA 2884
Query 3180 LCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALN 3239
TF+++ Y KL + + + Y A YN+YKY+SG + YR A +LAKA+
Sbjct 2885 AGTFVIDMRSYEKLANSI--SPEKLKSYAASYNRYKYYSGNANEADYRCACYAYLAKAML 2942
Query 3240 DFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVV 3299
DFS +D+LY PP S S LQ+G RKMA PSG VE C+V+V G T LNGLWL D+V
Sbjct 2943 DFSRDHNDILYTPPTVSYGST-LQAGLRKMAQPSGFVEKCVVRVCYGNTVLNGLWLGDIV 3001
Query 3300 YCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANP 3359
YCPRHVI ++ +Y+ HNF + +G L V+G +M LK+KV N
Sbjct 3002 YCPRHVIASNTT-SAIDYDHEYSIMRLHNFSIISGTAFLGVVGATMHGVTLKIKVSQTNM 3060
Query 3360 KTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDC 3419
TP++ F ++ G+ F++LACY+G GV+ MR N+TI+GSF+NG+CGS G+N+
Sbjct 3061 HTPRHSFRTLKSGEGFNILACYDGCAQGVFGVNMRTNWTIRGSFINGACGSPGYNLKNGE 3120
Query 3420 VSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGD 3479
V F YMH +EL +G H G+ +G YG F D+ Q + +TVNV+A+LYAA++NG
Sbjct 3121 VEFVYMHQIELGSGSHVGSSFDGVMYGGFEDQPNLQVESANQMLTVNVVAFLYAAILNGC 3180
Query 3480 RWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGM 3539
W+L + +N A + + + D L+A+TG+ V + +++ +L NG
Sbjct 3181 TWWLKGEKLFVEHYNEWAQANGFTAMNGE--DAFSILAAKTGVCVERLLHAIQ-VLNNGF 3237
Query 3540 NGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQ 3599
G+ ILG + L DEF+ +VV+Q GV QS K T + +++ V+ +
Sbjct 3238 GGKQILGYSSLNDEFSINEVVKQMFGVNLQSG-----KTTSMFKSISLFAGFFVMFWAEL 3292
Query 3600 W--SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPA 3657
+ + ++ PF + ++A+S VKHK FL +FLLPS+ A N +
Sbjct 3293 FVYTTTIWVNPGFLTPFMILLVALSLCLTFVVKHKVLFLQVFLLPSIIVAAIQNCAW--D 3350
Query 3658 SWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTL 3717
V +++ + S+ ++ V + + +L T R + L +++ +
Sbjct 3351 YHVTKVLAEKFDYNVSVMQMDIQGFVNIFICLFVALLHTWRFAKERCTHWCTYLFSLIAV 3410
Query 3718 VYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARG-IVFMCVEYCPIFFITGNTL 3776
+Y Y +S+ +++ SN + + + R + F+ VEY F + +
Sbjct 3411 LYTALYSY---DYVSLLVMLLCAISNEWYIGAIIFRICRFGVAFLPVEYVSYF----DGV 3463
Query 3777 QCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSID 3836
+ ++L Y LG+ Y+GL +NR+ + TLGVYD+ VS EF+YM + GL P D
Sbjct 3464 KTVLLFYMLLGFVSCMYYGLLYWINRFCKCTLGVYDFCVSPAEFKYMVANGLNAPNGPFD 3523
Query 3837 AFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHN 3896
A L+ KL+G+GG IKV+TVQSK++D+KCT+VVL+ +L + + S+SK WA CV++HN
Sbjct 3524 ALFLSFKLMGIGGPRTIKVSTVQSKLTDLKCTNVVLMGILSNMNIASNSKEWAYCVEMHN 3583
Query 3897 DILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA 3956
I L D A E +++LL+ LS + L + +N + LQ++AS F +PS+ A
Sbjct 3584 KINLCDDPETAQELLLALLAFFLSKHSDFGLGDLVDSYFENDSILQSVASSFVGMPSFVA 3643
Query 3957 FATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQA 4016
+ TA++ YE AVANG S ++K+LKK++NVAK+EFDR++++Q+K+ +MA+QA MYK+A
Sbjct 3644 YETARQEYENAVANGSSPQIIKQLKKAMNVAKAEFDRESSVQKKINRMAEQAAAAMYKEA 3703
Query 4017 RSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPD 4076
R+ ++++KV SAM ++LF MLR+LD +++ I+N AR+G VPL++IP T+AA+L+VV+PD
Sbjct 3704 RAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNMARNGVVPLSVIPATSAARLVVVVPD 3763
Query 4077 YNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSA 4136
++++ YA +W +Q+V D D K V L +++ +N L WPLI+T R
Sbjct 3764 HDSFVKMMVDGFVHYAGVVWTLQEVKDNDGKNVHLKDVTKENQEILVWPLILTCER---V 3820
Query 4137 VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARF 4196
VKLQNNE+ P ++ + ++ NAL YN G F+ A ++ +K+ ++
Sbjct 3821 VKLQNNEIMPGKMKVKATKGEGDGGITSEGNAL--YNNEGGRAFMYAYVTTKPGMKYVKW 3878
Query 4197 PKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGN 4256
G T+ ELEPPCRFV DTP GP++KYLYF+K LNNL RG VLG + ATVRLQAG
Sbjct 3879 EHDSGVVTV--ELEPPCRFVIDTPTGPQIKYLYFVKNLNNLRRGAVLGYIGATVRLQAGK 3936
Query 4257 ATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANM 4316
TE +NS +L+ C+FAVD A AY D + G +P+ NCVKML +G+GQAIT T ++N
Sbjct 3937 QTEFVSNSHLLTHCSFAVDPAAAYLDAVKQGAKPVGNCVKMLTNGSGSGQAITCTIDSNT 3996
Query 4317 DQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMW 4376
Q+++GGAS C+YCR H+ HP GFC KGK+VQ+P NDP+ F L+NTVC VCG W
Sbjct 3997 TQDTYGGASVCIYCRAHVAHPTMDGFCQYKGKWVQVPIG-TNDPIRFCLENTVCKVCGCW 4055
Query 4377 KGYGCSCDQLREPMLQSADAQSFLNRVC 4404
+GC+CD+ +QS D S+LN
Sbjct 4056 LNHGCTCDR---TAIQSFD-NSYLNESG 4079
Score = 257 bits (657), Expect = 2e-66, Method: Composition-based stats.
Identities = 125/768 (16%), Positives = 262/768 (34%), Gaps = 67/768 (9%)
Query 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEK-QV 1199
+ +S G + + +S +CVD N + L + + V
Sbjct 1193 CSSIFRGAVSCGHYQTNI-YSQNLCVDGFGVNKIQPWTNDALNTICIKDADYNAKVEISV 1251
Query 1200 EQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLE---ETKFLTENLLLY 1256
+ + F+ + K + + + V+ V ++ ENL
Sbjct 1252 TPIKNTVDTTPKEEFVVKEKLNAFLVHDNVAFYQGDVDTVVNGVDFDFIVNAANENLAHG 1311
Query 1257 IDINGNLHPDSATLVSDIDITFLKKDAPYIVGD-VVQEGVLTAV--VIPTKKAGGTTEML 1313
+ L + + + + VG V+ E + V+ +K ++L
Sbjct 1312 GGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTGVMVECDSLRIFNVVGPRKGKHERDLL 1371
Query 1314 AKALRKVPTDN--YITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTV 1371
KA + + +T G+ G +E + VL + + + + V
Sbjct 1372 IKAYNTINNEQGTPLTPILSCGIFGIKLETSLEVLLDVCNTKEV---KVFVYTDTEVCKV 1428
Query 1372 SWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTV 1431
+ ++ + + + VS I+ + + VD ++
Sbjct 1429 KDFVSGLVNVQKVEQPKI-----EPKPVSVIK-----VAPKPYRVDGKFSYF-------T 1471
Query 1432 ASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLT 1491
L+ +D + +V + L L++ + + + +S + D V +
Sbjct 1472 EDLLCVADD--KPIVL----FTDSMLTLDDRGLALDN-ALSGVLSAAIKDCVDINKAIPS 1524
Query 1492 SS-SKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEV 1550
+ K + + + S KD + + + V L
Sbjct 1525 GNLIKFDIGSVVVYMCVVPSEKDKHLDNNVQRCTRKLNRLMCDIVCTIPADYILPLVLSS 1584
Query 1551 ITFD-NLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKP 1609
+T + + L E + I + T D +N+H V ++ QQ G D++ P
Sbjct 1585 LTCNVSFVGELKAAEAKVITIKVTEDGVNVHDVTVTTDKSFEQQVGVIADKDKDLSGAVP 1644
Query 1610 HNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTK-KWKYPQVNGLTSIK 1668
+ + + + V+ E+Y D + ++H+ ++ VNG+ +K
Sbjct 1645 SDLNTSELL-----TKAIDVDWVEFYGFKD----AVTFATVDHSAFAYESAVVNGIRVLK 1695
Query 1669 WADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDV 1728
+DNNC++ + LQ + F L A+ + G+ F A + G+ GD
Sbjct 1696 TSDNNCWVNAVCIALQYSKPHFISQGLDAAWNKFVLGDVEIFVAFVYYVARLMKGDKGDA 1755
Query 1729 RETMSYLFQH-ANLDSCKRVLNVVCKTCGQQ-QTTLKGVEAVMYMGTLSYEQFKKGVQIP 1786
+T++ L ++ AN + C C + + ++ + + + ++ + + G
Sbjct 1756 EDTLTKLSKYLANEAQVQLEHYSSCVECDAKFKNSVASINSAIVCASVKRDGVQVGY--- 1812
Query 1787 CTCGKQATKYLVQQESPFVMMSA----PPAQYELKHGTFTCASEYTGNYQCGHYK-HITS 1841
C G + + +++S P AQ L G A ++G GHY + T+
Sbjct 1813 CVHGIKYYSRVRSVRGRAIIVSVEQLEPCAQSRLLSGVAYTA--FSGPVDKGHYTVYDTA 1870
Query 1842 KETLYCIDGALLTKSSEYKGPITDVF----YKENSYTTTIKPVTYKLD 1885
K+++Y DG K +T V Y T KPV +LD
Sbjct 1871 KKSMY--DGDRFVKHDLSLLSVTSVVMVGGYVAPVNTVKPKPVINQLD 1916
Score = 185 bits (469), Expect = 2e-44, Method: Composition-based stats.
Identities = 69/249 (28%), Positives = 108/249 (43%), Gaps = 16/249 (6%)
Query 991 QDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLK--------LTDNVYIKN 1042
Q + D T + ++E+ +TP+ T++ ++ + DNV
Sbjct 1226 QPWTNDALNTICIKDADYNAKVEISVTPIKNTVDTTPKEEFVVKEKLNAFLVHDNVAFYQ 1285
Query 1043 ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGS 1102
D+ V +VNAAN L HGGG+A AL+ T +Q S ++I G +KVG
Sbjct 1286 GDVDTVVNGVDFDFIVNAANENLAHGGGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTG 1345
Query 1103 CVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSL 1162
++ +L +VVGP K E L+K+ N+ L P+LS GIFG SL
Sbjct 1346 VMVECDSL--RIFNVVGPRKGKHERDLLIKAYNTINNEQGTPLTPILSCGIFGIKLETSL 1403
Query 1163 RVCVDTVRTN-VYLAVFDKNLYDK---LVSSFLEMKSEKQ--VEQKIAEIPKEEVKPFIT 1216
V +D T V + V+ K VS + ++ +Q +E K + K KP+
Sbjct 1404 EVLLDVCNTKEVKVFVYTDTEVCKVKDFVSGLVNVQKVEQPKIEPKPVSVIKVAPKPYRV 1463
Query 1217 ESKPSVEQR 1225
+ K S
Sbjct 1464 DGKFSYFTE 1472
Score = 100 bits (249), Expect = 6e-19, Method: Composition-based stats.
Identities = 58/271 (21%), Positives = 102/271 (38%), Gaps = 24/271 (9%)
Query 1657 KYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILA 1716
+ ++NGL +K DNNC++ + +L +Q + A+Q + G A
Sbjct 1037 PFEELNGLKILKQLDNNCWVNSVMLQIQLTGILDGDYAMQF----FKMGRVAKMIERCYT 1092
Query 1717 YCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSY 1776
G +GDV M L + +L + V++ C +C + G AV++ T +
Sbjct 1093 AEQCIRGAMGDVGLCMYRLLK--DLHTGFMVMDYKC-SCTSGRLEESG--AVLFC-TPTK 1146
Query 1777 EQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTF--TCASEYTGNYQCG 1834
+ F C + Q + + + P C+S + G CG
Sbjct 1147 KAF--PYGTCLNCNAPRMCTIRQLQGTIIFVQQKPEPVNPVSFVVKPVCSSIFRGAVSCG 1204
Query 1835 HYKHITSKETLYCIDGALLTKSSEY------KGPITDVFYKENSYTTTIKPVTYKLDGVV 1888
HY+ + L C+DG + K + I D Y ++ P+ +D
Sbjct 1205 HYQTNIYSQNL-CVDGFGVNKIQPWTNDALNTICIKDADYNAKVE-ISVTPIKNTVDTTP 1262
Query 1889 CTE--IDPKLDNYYKKDNSYFTEQPIDLVPN 1917
E + KL+ + DN F + +D V N
Sbjct 1263 KEEFVVKEKLNAFLVHDNVAFYQGDVDTVVN 1293
Score = 60.5 bits (145), Expect = 1e-06, Method: Composition-based stats.
Identities = 83/540 (15%), Positives = 164/540 (30%), Gaps = 69/540 (13%)
Query 171 RELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYC 230
+++ GG Y D CG DG P+ S L + +D +
Sbjct 101 FDVVFGKRGGGNVTYTDQYLCGADGKPV------------MSEDLWQFVDHFGENEEIII 148
Query 231 CREHEHEIAWYTERSEKSYELQTPFEIKLAKKF--DTFNGECPNFVFPLNSIIKTIQPRV 288
H + AW T+R Y+ Q I+ + D + V + +KT V
Sbjct 149 -NGHTYVCAWLTKRKPLDYKRQNNLAIEEIEYVHGDALHTLRNGSVLEMAKEVKTSSKVV 207
Query 289 EKKKLDGFMGRIRSVYPVASPNE----CNQMCLSTLMKCDHCGETSWQTGDFVKATCEFC 344
LD S N + +S L++C CG SW GD+
Sbjct 208 LSDALDKLYKVFGSPVMTNGSNILEAFTKPVFISALVQCT-CGTKSWSVGDWTG------ 260
Query 345 GTENLTKEGATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTI 404
++C + N + + V P ++ T + G
Sbjct 261 --------FKSSCCNVISNKLCVVP------GNVKPGDAVI---------TTQQAGAGIK 297
Query 405 AFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIV 464
F G +V + W A ++ C E +N + N+
Sbjct 298 YFCGMTLKFVANIEGVSVWRVIALQSVDCFVASSTFVEEEHVNR-------MDTFCFNVR 350
Query 465 GDFKLNEEIAIILASFSAST-----SAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKG 519
+A++ A +++ S ++ G + + I + V K + G
Sbjct 351 NSVTDECRLAMLGAEMTSNVRRQVASGVIDISTGW-FDVYDDIFAESKPWFVRKAEDIFG 409
Query 520 AWNIGEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYS-- 577
S L L E R V+SI + + ++++L L+ +
Sbjct 410 PC-WSALASALKQLKVTTGELVRFVKSICNSAVAVVGGTIQILASVPEKFLNAFDVFVTA 468
Query 578 -LRLIDAMMFTSDLAT---NNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEE 633
+ D + T +A + + + +V+L + L + K+K +
Sbjct 469 IQTVFDCAVETCTIAGKAFDKVFDYVLLDNALVKLVTTKLKGVRERGLNKVKYATVVVGS 528
Query 634 KFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSI 693
+ + ++ + + G V +F+L+ ++ ++
Sbjct 529 TEEVKSSRVERSTAVLTIANNYSKLFDEGYTVVIGDVAYFVSDGYFRLMASPNSVLTTAV 588
>sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus
512/2005 OX=693999 GN=1a PE=3 SV=1
Length=4128
Score = 2595 bits (6725), Expect = 0.0, Method: Composition-based stats.
Identities = 807/2438 (33%), Positives = 1250/2438 (51%), Gaps = 155/2438 (6%)
Query 2000 KATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQK 2059
+T T + + ST V S VLK G+D+ C P+ + VV
Sbjct 1814 TSTTCDGTCSTKRVVSTPVVNAS----VLKV----GLDDGNCVHGLPLVDRVVSVNGTVI 1865
Query 2060 DVLECNVKTTEVVG-DIILKPANNSLKITEEVGHTDLMAAYVDNSSLT----IKKPNELS 2114
+ VV + +L + + + + L + KP +L+
Sbjct 1866 ITNVGDTPGKPVVATENLLLDGVSYTVFQDSTTGVGHYTVFDKEAKLMFDGDVLKPCDLN 1925
Query 2115 RVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVT--RCLNRVCTNYMPYF 2172
+ + V P + A FL+ + + T ++R + Y
Sbjct 1926 VSPVTSVVVCNNKKIVVQDPVKRVELDASKFLDTMNVASEKFFTFGDFVSRNIIVLIVYL 1985
Query 2173 FTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIW 2232
F+LL + + ++ A +P +SV K+ +A + + I
Sbjct 1986 FSLLAICFRALKKRDMKVMAGVPERTGIILKRSV-KYNYKALKFFFRLK-----FQYIKV 2039
Query 2233 FLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCL 2292
FL S+ L +L Y+ + + + +G P C Y +GY NST YC + C +CL
Sbjct 2040 FLKFSLVLYTL-YALMFMFIRFTPVGTP-ICKRYTDGYANST-FDKNDYCGN-VLCKICL 2095
Query 2293 SGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFS 2352
G + L + I + L L + + I+F FF +G+ + + +
Sbjct 2096 YGYEELSDFTHTRVIWQHLKDP---LIGNILPLFYLVFLIIFGGFFVRIGITYFIMQYIN 2152
Query 2353 Y--FAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCM 2410
A+ + N WL+ L+ P ++M + + + HV+ GC+ +C+
Sbjct 2153 AAGVALGYQDNVWLLHLL-------PFNSMGNIIVVAFIVTRILLFLKHVLFGCDKPSCI 2205
Query 2411 MCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVA 2470
C K + TRV TI+ GV +SFYV ANGGK FCK HN+ CV+CD++ G TFI+D +A
Sbjct 2206 ACSKSAKLTRVPLQTILQGVTKSFYVNANGGKKFCKKHNFFCVDCDSYGYGCTFINDVIA 2265
Query 2471 RDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRAN 2530
+LS K + PT ++ I+D V NG +LY K + + + D L+
Sbjct 2266 PELSNVTKLNVIPTGPATIIIDKVEFSNGFYYLYSGSTFWKYNFDITEAKYACKDVLKNC 2325
Query 2531 NTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKM 2590
N + + +VF S + K+A VY+SQL+C+PI L+D AL++ + + + +
Sbjct 2326 N----ILTDFVVF-NNSGSNVTQVKNACVYFSQLLCKPIKLVDSALLASLN--VDFSANL 2378
Query 2591 FDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKD 2650
A+V S++F + + + R+ SDV ++
Sbjct 2379 HKAFVEVLSNSFGKDLSNCSNM----------------------NECRESLGLSDVPEEE 2416
Query 2651 VVECLKLSHQSDIEVTGDSCNNYMLTYNKVE-NMTPRDLGACIDCSARHINAQVAKSHNI 2709
+ +H+ D+ ++ S NN +++Y K E + D+ C+ A+ +N V N+
Sbjct 2417 FSAAVSEAHRYDVLISDVSFNNLIVSYAKPEEKLAVHDIANCMRVGAKVVNHNVLTKDNV 2476
Query 2710 ALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNW 2769
++W KDF++LSE+ RK I K + F LT R + + T +A K G + +
Sbjct 2477 PVVWLAKDFIALSEEARKYIVRTTKTKGINFMLTFNDRRMHLTIPTISVANKKGAGLPSL 2536
Query 2770 LKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEI-----IGYKAIDGGVTRDIASTD 2824
+L + F + LI + V + DFS+++ +K I+ GV +
Sbjct 2537 FTRL------YSFFWHLCVLIVVLFVATSLLDFSAQVTSDTQYDFKYIENGVLKVFEKPL 2590
Query 2825 TCFANKHADFDTWFSQRGGS-YTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLH 2883
C N +F+ W + + GS TN + CP++ +PG+P + G L
Sbjct 2591 DCVHNAFVNFNEWHNAKFGSIPTNSRRCPIVVGTSDEV--RYIPGVPAGVFLY--GKSLI 2646
Query 2884 FLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSV 2943
F +C+ L + +C+ + CT G+ V YCY V++ +
Sbjct 2647 FAMSTIFGTSGLCFDDRGLTD-----PDSCIFNSACTTLSGIGGRNV-YCYREGVVDNAK 2700
Query 2944 AYESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCERSEAGVCVSTSG 3002
Y SL P + Y LMDG+ I P G +R + T YCR G C S+AGVCV
Sbjct 2701 LYSSLLPHSYYRLMDGNHIVLPEIITRGFGIRTIKTQAMTYCRTGECIDSQAGVCVGLDR 2760
Query 3003 RWVLNNDYYRSLPG--VFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL 3060
+V Y PG CG +LL N+ I +S I+ +VA
Sbjct 2761 FFV-----YSKTPGSDYVCGTGFFSLLFNVIGMFSNSIPVTVMSGQILLNCVVAFTAVMA 2815
Query 3061 AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDV 3120
+ F +F+R FG+ S V L +++ +T + + Y L F T V
Sbjct 2816 CFAFTKFKRLFGDMSFGVLSVGLCTVVNNLSYVVTQ-----NSIGMLAYATLYFLCTKGV 2870
Query 3121 --SFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFNGVSF-ST 3174
S++ H+ + + + L P+W+ +AY+IC F N K +V +F G F +
Sbjct 2871 RYSWVWHVGFAISYCFLAPWWVVLAYLIC----ALLEFLPNLFKLKVSTQLFEGDKFVGS 2926
Query 3175 FEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL 3234
FE AA TF+L+ Y KL + + + +Y A YN+YKY+SG+ YR A HL
Sbjct 2927 FESAASGTFVLDMHSYQKLANSI--STEKLKQYCASYNRYKYYSGSASEADYRLACFAHL 2984
Query 3235 AKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLW 3294
AKA++DF+N D LY PP S S LQ+G RKMA PSG VEGC+V+V+ G TLNGLW
Sbjct 2985 AKAMSDFANDHMDKLYTPPTVSYNST-LQAGLRKMAQPSGIVEGCIVRVSYGNLTLNGLW 3043
Query 3295 LDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKV 3354
L D V CPRHVI ++ +Y+ + HNF + +GN+ L VI SM+ +L +KV
Sbjct 3044 LGDTVICPRHVIASNTT-NVIDYDHAMSLVRLHNFSISSGNMFLGVISASMRGTLLHIKV 3102
Query 3355 DTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFN 3414
+ +N TP Y + ++PG +F++LACY+GS +GVY MR N+TI+GSF++G+CGS G+N
Sbjct 3103 NQSNVNTPNYTYKVLKPGDSFNILACYDGSAAGVYGVNMRTNYTIRGSFISGACGSPGYN 3162
Query 3415 IDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAA 3474
I+ V FCYMHH+EL +G H G+D++G YG + D+ T Q G +T NV +WLY A
Sbjct 3163 INNGVVEFCYMHHLELGSGCHVGSDMDGTMYGKYEDQPTLQIEGASNLVTENVCSWLYGA 3222
Query 3475 VINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKEL 3534
+INGDRW+L+ + ++ +N A++ L +VD L A+TG+ V + AS+++L
Sbjct 3223 LINGDRWWLSSVSVGVDTYNEWALRNGMTALK--NVDCFSLLVAKTGVDVGRLLASIQKL 3280
Query 3535 LQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSA-VKRTIKGTHHWLLLTILTSLLV 3593
N G++ILG L DEFT +VV+Q GVT QS V R + +I+ LL
Sbjct 3281 HGN-FGGKSILGCTSLCDEFTLSEVVKQMYGVTLQSGKVSRAFRN------ASIVCCLLF 3333
Query 3594 LVQSTQW--SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN 3651
L S S F++ P + II S+ M+ VKHK FL L+LLPSL V+ +N
Sbjct 3334 LFLSEMLNHSKLFWINPGYITPVFLAIIVASSALMLLVKHKLLFLQLYLLPSLCIVSGYN 3393
Query 3652 MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVW-T 3710
++ + ++ D GF + + + ++ L T R + +++
Sbjct 3394 -IFKDYHFYTYMLEEFDY-KVPFGGFNVTGVLNISLCCFVMGLHTFRFL--QTPNKIFSY 3449
Query 3711 LMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFF 3770
++ VLT++Y YY + + +S +NY + T LA +
Sbjct 3450 VVAVLTVLYTYYYS---TDVLGLILTSMSGFTNYWFIGTATYKLATYV-----LPHTSLL 3501
Query 3771 ITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLP 3830
+ + ++ ++ +Y LGY Y+G +NR+ +LTLG Y++ VS EF+YM + GL
Sbjct 3502 DSFDAIKAVVFLYLLLGYCNCVYYGSLYWINRFCKLTLGCYEFKVSAAEFKYMVANGLRA 3561
Query 3831 PKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQ 3890
P DA L++KL+GVGG+ IK+++VQSK++D+KCT+VVLL L + + ++S+ WA
Sbjct 3562 PTGVFDALILSLKLIGVGGRKTIKISSVQSKLTDLKCTNVVLLGCLSNMNIAANSREWAY 3621
Query 3891 CVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSS 3950
CV LHN I L D A E +++LL+ LS A +++L + ++ + LQ++A+ + +
Sbjct 3622 CVDLHNKINLCNDAEAAQEMLLALLAFFLSKNSAFGVDELLDSYFNDSSVLQSVAATYVN 3681
Query 3951 LPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMT 4010
LPSY A+ TA+++YE A+ANG ++K+L+ ++NVAKSEFDR+A+ QRKL++MA+QA +
Sbjct 3682 LPSYLAYETARQSYEDALANGSPPQLVKQLRHAMNVAKSEFDREASTQRKLDRMAEQAAS 3741
Query 4011 QMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKL 4070
QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I++ A+DG VPL+IIP +A KL
Sbjct 3742 QMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLAKDGVVPLSIIPAVSATKL 3801
Query 4071 MVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTA 4130
+V+ D +Y YA +W + + D D K V E+ N +LAWPL +
Sbjct 3802 NIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAKEVVTSNVESLAWPLFLNC 3861
Query 4131 LRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQD 4190
R +KLQNNE+ P ++Q A D NAL Y+ G F+ A +SD D
Sbjct 3862 ER---IIKLQNNEIIPSKIKQRPIKAEGE-GVVADGNAL--YSNEGGRTFMYAFISDKPD 3915
Query 4191 LKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATV 4250
LK ++ G+ I ELEPPC+F+ + P GP VKYLYF++ LNNL RG VLG + ATV
Sbjct 3916 LKVVKWEFDGGSNAI--ELEPPCKFLVEAPSGPVVKYLYFVRNLNNLRRGAVLGFIGATV 3973
Query 4251 RLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITV 4310
RLQAG TE NS++L+ CAFAVD K Y D + SG +P+ NCVKML +G GQAIT
Sbjct 3974 RLQAGKQTEQATNSSLLTLCAFAVDPPKTYLDAVKSGHRPVGNCVKMLANGSGNGQAITN 4033
Query 4311 TPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVC 4370
EA+ +Q+S+GGAS CLYCR H++HP+ GFC L+GKYVQ+P DP+ F L+NTVC
Sbjct 4034 GVEASTNQDSYGGASVCLYCRAHVEHPDMDGFCKLRGKYVQVPLGTL-DPIRFVLENTVC 4092
Query 4371 TVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSA 4408
VCG W+ GC+CD+ ++QS D +LN CG
Sbjct 4093 KVCGCWQANGCTCDR---AVIQSVD-SGYLNE-CGALV 4125
Score = 216 bits (551), Expect = 5e-54, Method: Composition-based stats.
Identities = 84/363 (23%), Positives = 129/363 (36%), Gaps = 36/363 (10%)
Query 1561 SLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYV 1620
+L E + ++V T D + HT + S TYGQQ G ++ VT +KP + K V
Sbjct 1634 TLFEAKPVQVVVTQDQRSFHTVELSTSQTYGQQLGDCVVEDKKVTNLKPVSKD--KVVSV 1691
Query 1621 LPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTK-KWKYPQVNGLTSIKWADNNCYLATA 1679
+PN V+ ++Y D L+HT + VNG ++ +DNNC++
Sbjct 1692 VPN-----VDWDKHYGFVDAGI----FHTLDHTMFVFDNNVVNGKRVLRTSDNNCWINAV 1742
Query 1680 LLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHA 1739
L LQ KF P LQ + G+ A F + GE D T++ + +
Sbjct 1743 CLQLQFANAKFKPKGLQQLWESYCTGDVAMFVHWLYWITGVEKGEPSDAENTLNIISRFL 1802
Query 1740 NLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQ 1799
+L TC +T + V + ++ G C G +V
Sbjct 1803 KPQGSVEMLRATSTTCDGTCSTKRVVSTPVVNASVLKVGLDDG---NCVHGLPLVDRVVS 1859
Query 1800 QESPFVMMSA--PP------AQYELKHGTFTCASEYT-GNYQCGHYKHITSKETLYCIDG 1850
++ + P + L G + GHY + KE DG
Sbjct 1860 VNGTVIITNVGDTPGKPVVATENLLLDGVSYT--VFQDSTTGVGHYT-VFDKEAKLMFDG 1916
Query 1851 ALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPK--LDNYYKKDNSYFT 1908
+L P+T V N K V D V E+D LD +FT
Sbjct 1917 DVLKPCDLNVSPVTSVVVCNNK-----KIVVQ--DPVKRVELDASKFLDTMNVASEKFFT 1969
Query 1909 EQP 1911
Sbjct 1970 FGD 1972
Score = 172 bits (436), Expect = 1e-40, Method: Composition-based stats.
Identities = 73/265 (28%), Positives = 108/265 (41%), Gaps = 19/265 (7%)
Query 993 GSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKV 1052
G + TI T+ E+ + +V F Y N+ ++ V
Sbjct 1268 GRHPIKFNTINTLCYKDVDWEVS----NGSCDVKPFLTY----KNIEFYQGELSALL-SV 1318
Query 1053 KPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAK 1112
VVNAAN L HGGG+A AL+ T +QV S+ Y++ NG +KVG ++
Sbjct 1319 NHDFVVNAANEQLSHGGGIAKALDDLTKGELQVLSNQYVSRNGSIKVGSGVLIKCKE--H 1376
Query 1113 HCLHVVGPNVNKGEDIQLLKSAYE-NFNQHEVLLAPLLSAGIFGADPIHSLR---VCVDT 1168
L+VVGP K +LL AY F Q V L PLLS GIF SL CV
Sbjct 1377 SILNVVGPRKGK-HAAELLTKAYTFVFKQKGVPLMPLLSVGIFKVPITESLAAFLACVGD 1435
Query 1169 VRTNVYLAVFDKNL-YDKLVSSFLEMK--SEKQVEQKIAEIPKEEVKPFITESKPSVEQR 1225
+ + L V+SF + V Q++ + E+ P + P R
Sbjct 1436 RVCKCFCYTDKERLAIQNFVTSFQTEQPVEPLPVIQEVKGVQLEKPVPDVKVENPCEPFR 1495
Query 1226 KQDDKKIKACVEEVTTTLEETKFLT 1250
+ D K + +L+ T+ ++
Sbjct 1496 IEGDAKFYDLTPSMVQSLQVTRLVS 1520
Score = 65.5 bits (158), Expect = 3e-08, Method: Composition-based stats.
Identities = 37/190 (19%), Positives = 64/190 (34%), Gaps = 14/190 (7%)
Query 1649 ALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAA 1708
+ Y GL + + NNC++++AL+ LQ L + +Q AG +
Sbjct 1078 VKPDVFAFSYASYGGLKVLNQSSNNCWVSSALVQLQLTGL-LDSDEMQL----FNAGRVS 1132
Query 1709 NFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAV 1768
G LGDV + L + + S ++ C ++ E
Sbjct 1133 PMVKRCYESQRAIFGSLGDVSACLESLLKDRDGMSITCTIDCGCGP------GVRVYENA 1186
Query 1769 MYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMM-SAPPAQYELKHGTFTCASEY 1827
++ T F G + C+ K + Q + + A + CA+ Y
Sbjct 1187 IFRFTPLKTAFPMGRCLICS--KTLMHTITQMKGTGIFCRDATALDVDTLVVKPLCAAVY 1244
Query 1828 TGNYQCGHYK 1837
G GHY
Sbjct 1245 VGAQDGGHYL 1254
Score = 61.2 bits (147), Expect = 6e-07, Method: Composition-based stats.
Identities = 55/380 (14%), Positives = 122/380 (32%), Gaps = 40/380 (11%)
Query 653 STCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTH 712
V + +++ F V F+ + + + + +
Sbjct 750 LNGVVVFVTKKFRKAGALLQKLYNAFLDTVTSFIKVAGVAFKYCATCVPKIVIN------ 803
Query 713 SKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSE 772
G Y + + L +P + + V + LE +
Sbjct 804 --GCYHTVTRLFAK-DLQIPTEDG------VADFNTFNHCVFPVNPTRIETDSLELEEVD 854
Query 773 AVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIE 832
VE + G V ++ T Y + V + F KGG ++ + V
Sbjct 855 FVEPGVDGKLVILDDYSFYS-DGTNYYP--SDGKGVVASCFKKKGGGVVTIS-DEVQVRT 910
Query 833 VQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTP 892
+ V + +E + D+ L + C +GT++ V L+ + + +
Sbjct 911 IDPVYKVRLEYEFE---DETLVKVC---EKAIGTKLK-----VTGDWSNLLETLEKAMDV 959
Query 893 LGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTE 952
+ LD + Y+++DE G L + S +P D E ++F+
Sbjct 960 VRQHLD---VPDYFVYDEEGGTDLNLTIMVSQWPLSSDSE------DDFKAVDDEPNANT 1010
Query 953 DDYQGKPLEFGATSAALQPEEEQEE-DWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQ 1011
D+ E A + +Q + Q+E + + D + + + + + + +
Sbjct 1011 DETVDTFAEDVAETQNVQQDVTQDEVEAVCDLVVKATEEGPIEHEELSEDQKEVQQALAF 1070
Query 1012 LEMELTPVVQTIEVNSFSGY 1031
+E + V + S++ Y
Sbjct 1071 IEDKPVVVKPDVFAFSYASY 1090
Score = 52.4 bits (124), Expect = 2e-04, Method: Composition-based stats.
Identities = 40/209 (19%), Positives = 64/209 (31%), Gaps = 39/209 (19%)
Query 172 ELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCC 231
+L+ GG VD CG DG P+ + G + +D+ +
Sbjct 102 DLVFGRCGGTTIP-VDQFMCGADGAPV-------IQEGDWTF-----MDYFQ-DSNQFTL 147
Query 232 REHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQ-PRVEK 290
+ AW +R Y Q I+ V + +KT + P+V K
Sbjct 148 NGITYVKAWDVDRKPNDYAKQNVTCIRRITYITDH-----RHVLADGTTMKTARHPKVNK 202
Query 291 KKLDG-------------FMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFV 337
+ FMG + V + L+ C+ CG + W GD+
Sbjct 203 SVVLDSPFDQIYKEVGSPFMGNGSTF--VEMLKDPAFFH--ALITCE-CGRSEWTVGDW- 256
Query 338 KATCEFCGTENLTKEGATTCGYLPQNAVV 366
K C T +P V+
Sbjct 257 KGYNSLCCNIKCKPITIVTPKAVPGAVVI 285
>sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=1a PE=1 SV=1
Length=4117
Score = 2584 bits (6698), Expect = 0.0, Method: Composition-based stats.
Identities = 769/2444 (31%), Positives = 1221/2444 (50%), Gaps = 169/2444 (7%)
Query 2018 PVETSNSFDVLKSEDAQGMDNLACE---DLKPVSEEVVENPTIQKDVLE----------- 2063
P ++ N+ ++L D S+ VV P + VL+
Sbjct 1780 PSDSENALNMLSKYIVPAGSVTIERVTHDGCCCSKRVVTAPVVNASVLKLGVEDGLCPHG 1839
Query 2064 --CNVKTTEVVGDIILKPANNSLKITEEVGHTDL-MAAYVDNSSLTI------------- 2107
K V G I+ + + + ++DN + +
Sbjct 1840 LNYIGKVVVVKGTTIVVNVGKPVVAPSHLFLKGVSYTTFLDNGNGVVGHYTVFDHGTGMV 1899
Query 2108 -----KKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVT--RC 2160
P +L+ + + A V P A L+ + + +
Sbjct 1900 HDGDAFVPGDLNVSPVTNVVVSEQTAVVIKDPVKKAELDATKLLDTMNYASERFFSFGDF 1959
Query 2161 LNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKS 2220
++R Y ++L R + ++ A +P KS+ ++ +A + K
Sbjct 1960 MSRNLITVFLYILSILGLCFRAFRKRDVKVLAGVPQRTGIILRKSM-RYNAKALGVFFKL 2018
Query 2221 PNFSKLINIIIWFLLLS-VCLG-SLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTI 2278
+ WF +L LG +Y+ + + + +G P C GY NS+
Sbjct 2019 K--------LYWFKVLGKFSLGIYALYALLFMTIRFTPIGSP-VCDDVVAGYANSS-FDK 2068
Query 2279 ATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKW-DLTAFGLVAEWFLAYILFTRF 2337
YC S+ C VCL G L + + + + ++ F +A + ++ +
Sbjct 2069 NEYC-NSVICKVCLYGYQELSDFSHTQVVWQHLRDPLIGNVMPFFYLAFLAIFGGVYVKA 2127
Query 2338 FYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSY 2397
+ + + + + I +Q+ P + F V
Sbjct 2128 ITLYFIFQYLNSLGVFLG---------LQQSIWFLQLVPFDVFGDEIVVFFIVTRVLMFI 2178
Query 2398 VHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDT 2457
HV GC+ ++C+ C K R RV TI G +SFYV+ANGG FCK HN+ C+NCD+
Sbjct 2179 KHVCLGCDKASCVACSKSARLKRVPVQTIFQGTSKSFYVHANGGSKFCKKHNFFCLNCDS 2238
Query 2458 FCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHS 2517
+ G TFI+D +A ++ K + PT ++ ++D V NG +LY K +
Sbjct 2239 YGPGCTFINDVIATEVGNVVKLNVQPTGPATILIDKVEFSNGFYYLYSGDTFWKYNFDIT 2298
Query 2518 LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALV 2577
S + + L+ S+ + IVF+ + K+A VY+SQ++C+P+ L+D AL+
Sbjct 2299 DSKYTCKEALK----NCSIITDFIVFNNNG-SNVNQVKNACVYFSQMLCKPVKLVDSALL 2353
Query 2578 SDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNV-LSTFISA 2636
+ + S + + A+V+ S++F + + + + D+V L TF +A
Sbjct 2354 ASL--SVDFGASLHSAFVSVLSNSFGKDLSSCNDM-----QDCKSTLGFDDVPLDTFNAA 2406
Query 2637 ARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTP-RDLGACIDCS 2695
+ +H+ D+ +T S NN+ +Y K E P D+ C+
Sbjct 2407 VAE------------------AHRYDVLLTDMSFNNFTTSYAKPEEKFPVHDIATCMRVG 2448
Query 2696 ARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVT 2755
A+ +N V +I ++W V+DF++LSE+ RK I K + F LT R + T
Sbjct 2449 AKIVNHNVLVKDSIPVVWLVRDFIALSEETRKYIIRTTKVKGITFMLTFNDCRMHTTIPT 2508
Query 2756 TKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGG 2815
IA K G + ++ K + LF+ A F+ ++ + ++ + S +K I+ G
Sbjct 2509 VCIANKKGAGLPSFSKVKKFFWFLCLFIVAAFFALSFLDFSTQVSSDSD--YDFKYIESG 2566
Query 2816 VTRDIASTDTCFANKHADFDTWFSQRGGS-YTNDKACPLIAAVITREVGFVVPGLPGTIL 2874
+ + +C N +FD W + G N+ +CP++ V + VPG+P +
Sbjct 2567 QLKTFDNPLSCVHNVFINFDQWHDAKFGFTPVNNPSCPIVVGV--SDEARTVPGIPAGVY 2624
Query 2875 RTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCY 2934
G L F +C+ S + + AC+ + CT G V YCY
Sbjct 2625 LA--GKTLVFAINTIFGTSGLCFDASGVAD-----KGACIFNSACTTLSGLGGTAV-YCY 2676
Query 2935 DTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCERSE 2993
++EG+ Y L P + Y ++DG+ + P G +R + T YCR G C +S
Sbjct 2677 KNGLVEGAKLYSELAPHSYYKMVDGNAVSLPEIISRGFGIRTIRTKAMTYCRVGQCVQSA 2736
Query 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
GVC +V N + S CG LL N+ + + + +S I+ I+
Sbjct 2737 EGVCFGADRFFVYNAE---SGSDFVCGTGLFTLLMNVISVFSKTVPVTVLSGQILFNCII 2793
Query 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
A V + + F +F+R FG+ S V L++ +T + + Y L
Sbjct 2794 AFVAVAVCFLFTKFKRMFGDMSVGVFTVGACTLLNNVSYIVTQ-----NTLGMLGYATLY 2848
Query 3114 FYLTNDVS--FLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFN 3168
F T V ++ H+ +++ + + P+W+ + Y + + F N K +V +F
Sbjct 2849 FLCTKGVRYMWIWHLGFLISYILIAPWWVLMVY----AFSAIFEFMPNLFKLKVSTQLFE 2904
Query 3169 GVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYR 3227
G F +FE AA TF+L+ Y +L + + + +Y + YNKYKY+SG+ YR
Sbjct 2905 GDKFVGSFENAAAGTFVLDMHAYERLANSI--STEKLRQYASTYNKYKYYSGSASEADYR 2962
Query 3228 EAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGT 3287
A HLAKA+ D++++ +D LY PP S S LQ+G RKMA PSG VE C+V+V G
Sbjct 2963 LACFAHLAKAMMDYASNHNDTLYTPPTVSYNST-LQAGLRKMAQPSGVVEKCIVRVCYGN 3021
Query 3288 TTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQN 3347
LNGLWL D+V CPRHVI +S +Y+ L HNF + +GNV L V+ +M+
Sbjct 3022 MALNGLWLGDIVMCPRHVIASSTTST-IDYDYALSVLRLHNFSISSGNVFLGVVSATMRG 3080
Query 3348 CVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGS 3407
+L++KV+ N TPKY + ++PG++F++LACY+G+ +GVY MR N+TI+GSF+NG+
Sbjct 3081 ALLQIKVNQNNVHTPKYTYRTVRPGESFNILACYDGAAAGVYGVNMRSNYTIRGSFINGA 3140
Query 3408 CGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNV 3467
CGS G+NI+ V FCY+H +EL +G H G+DL+G YG + D+ T Q G + T NV
Sbjct 3141 CGSPGYNINNGTVEFCYLHQLELGSGCHVGSDLDGVMYGGYEDQPTLQVEGASSLFTENV 3200
Query 3468 LAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDM 3527
LA+LYAA+ING W+L+ ++ FN A+ + + D L+A+TG+ V +
Sbjct 3201 LAFLYAALINGSTWWLSSSRIAVDRFNEWAVHNGMTTVG--NTDCFSILAAKTGVDVQRL 3258
Query 3528 CASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSA-VKRTIKGTHHWLLLT 3586
AS++ L +N G+ ILG L DEFT +VVRQ GV Q V R + +
Sbjct 3259 LASIQSLHKN-FGGKQILGHTSLTDEFTTGEVVRQMYGVNLQGGYVSRACRN------VL 3311
Query 3587 ILTSLLVLVQS--TQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSL 3644
++ S L S ++ FF++ P + +S+ M +KHK F +FL+P+L
Sbjct 3312 LVGSFLTFFWSELVSYTKFFWVNPGYVTPMFACLSLLSSLLMFTLKHKTLFFQVFLIPAL 3371
Query 3645 ATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILM---TARTVY 3701
+ N+ + + + SL GF + V V+ IL T R
Sbjct 3372 IVTSCINLAFDVEVY--NYLAEHFDYHVSLMGFNAQGLVNIFVCFVVTILHGTYTWRFFN 3429
Query 3702 DDGARRVWTLMNVLTLVYKVYYGNA-LDQAISMWALIISVTSNYSGVVTTVMFLARGIVF 3760
A V ++ +LT Y +Y + L A++++A SVT N V V + + V+
Sbjct 3430 -TPASSVTYVVALLTAAYNYFYASDILSCAMTLFA---SVTGN--WFVGAVCY--KVAVY 3481
Query 3761 MCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEF 3820
M + + P F ++ +M Y LGYF C++G+ NR+F++++GVYDY VS EF
Sbjct 3482 MALRF-PTFVAIFGDIKSVMFCYLVLGYFTCCFYGILYWFNRFFKVSVGVYDYTVSAAEF 3540
Query 3821 RYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLR 3880
+YM + GL P ++D+ L+ KL+G+GG+ IK+++VQSK++D+KC++VVLL L +
Sbjct 3541 KYMVANGLRAPTGTLDSLLLSAKLIGIGGERNIKISSVQSKLTDIKCSNVVLLGCLSSMN 3600
Query 3881 VESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRAT 3940
V ++S WA CV LHN I L D +A E +++LL+ LS A ++ L E ++ +
Sbjct 3601 VSANSTEWAYCVDLHNKINLCNDPEKAQEMLLALLAFFLSKNSAFGLDDLLESYFNDNSM 3660
Query 3941 LQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRK 4000
LQ++AS + LPSY + A++ YE AV NG ++K+L+ ++NVAKSEFDR+A+ QRK
Sbjct 3661 LQSVASTYVGLPSYVIYENARQQYEDAVNNGSPPQLVKQLRHAMNVAKSEFDREASTQRK 3720
Query 4001 LEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLN 4060
L++MA+QA QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I+N A+DG VPL+
Sbjct 3721 LDRMAEQAAAQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNLAKDGVVPLS 3780
Query 4061 IIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSP 4120
+IP +A KL +V D ++Y YA +W I + D D K+V + E++ N+
Sbjct 3781 VIPAVSATKLNIVTSDIDSYNRIQREGCVHYAGTIWNIIDIKDNDGKVVHVKEVTAQNAE 3840
Query 4121 NLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRF 4180
+L+WPL++ R VKLQNNE+ P L+Q S A A YN G F
Sbjct 3841 SLSWPLVLGCER---IVKLQNNEIIPGKLKQRSIKAEGDGIV---GEGKALYNNEGGRTF 3894
Query 4181 VLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRG 4240
+ A +SD DL+ ++ G TI ELEPP +F+ D+P G ++KYLYF++ LN L RG
Sbjct 3895 MYAFISDKPDLRVVKWEFDGGCNTI--ELEPPRKFLVDSPNGAQIKYLYFVRNLNTLRRG 3952
Query 4241 MVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCT 4300
VLG + ATVRLQAG TE NS++L+ CAFAVD AK Y D + SG +P+ NCVKML
Sbjct 3953 AVLGYIGATVRLQAGKQTEQAINSSLLTLCAFAVDPAKTYIDAVKSGHKPVGNCVKMLAN 4012
Query 4301 HTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDP 4360
+G GQA+T EA+ +Q+S+GGAS CLYCR H++HP+ GFC LKGKYVQ+P DP
Sbjct 4013 GSGNGQAVTNGVEASTNQDSYGGASVCLYCRAHVEHPSMDGFCRLKGKYVQVPLGTV-DP 4071
Query 4361 VGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVC 4404
+ F L+N VC VCG W GC+CD+ + + ++LN
Sbjct 4072 IRFVLENDVCKVCGCWLSNGCTCDR----SIMQSTDMAYLNEYG 4111
Score = 167 bits (424), Expect = 3e-39, Method: Composition-based stats.
Identities = 115/706 (16%), Positives = 224/706 (32%), Gaps = 61/706 (9%)
Query 1192 EMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTE 1251
++ + + + + VKPF + + +K + V E
Sbjct 1271 DVNWTAPLVPAVDSVVEPVVKPFYSYKNVD-FYQGDFSDLVKLPCDFVVNAANEKLSHGG 1329
Query 1252 NLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVG-DVVQEGVLTAV--VIPTKKAGG 1308
+ ID+ + ++ ++K P VG V+ E + V V+ +K
Sbjct 1330 GIAKAIDVY------TKGMLQKCSNDYIKAHGPIKVGRGVMLEALGLKVFNVVGPRKGKH 1383
Query 1309 TTEMLAKALRKVPTDNYI--TTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQE 1366
E+L KA + V ++ + T G+ +EE+ + C + ++++E
Sbjct 1384 APELLVKAYKSVFANSGVALTPLISVGIFSVPLEESLSAFLACVGDRHCKCFCYGDKERE 1443
Query 1367 ILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVD-YGARFYFY 1425
+ L + + E PV + + + K + GA ++
Sbjct 1444 AIIKYMDGLVDAI-FKEALVDTTPVQEDVQQVSQ------KPVLPNFEPFRIEGAHAFYE 1496
Query 1426 TSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPAT---VSVSSPDA 1482
+ + SL L + L+ + + + A ++V
Sbjct 1497 CNPEGLMSLGADKLVL----------FTNSNLDFCSVGKCLNDVTSGALLEAINVFKKSN 1546
Query 1483 VTAYNGYLTSSSKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPT 1542
T G + + ++ + + + LK K V + T
Sbjct 1547 KTVPAGNCVTLDCANMISITMVVLPFDGDANYDKNYARAVVKVSKLK--GKLVLAVDDAT 1604
Query 1543 TFHLDGEVITFDNLKT---LLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYL 1599
+ + + T + +++ + T D ++ V+ + TYGQQ GP +
Sbjct 1605 LYSKLSHLSVLGFVSTPDDVERFYANKSVVIKVTEDTRSVKAVKVESTATYGQQIGPCLV 1664
Query 1600 DGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTK-KWKY 1658
+ VT KP + V+PN +Y L+HT +
Sbjct 1665 NDTVVTDNKPVVAD--VVAKVVPN-----ANWDSHYGFDKAGE----FHMLDHTGFTFPS 1713
Query 1659 PQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYC 1718
VNG IK DNNC++ L LQ +F LQ + G+ A F +
Sbjct 1714 EVVNGRRVIKTTDNNCWVNVTCLQLQFARFRFKSAGLQAMWESYCTGDVAMFVHWLYWLT 1773
Query 1719 NKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQ 1778
G+ D ++ L ++ + V C + + V A + ++
Sbjct 1774 GVDKGQPSDSENALNMLSKYIVPAGSVTIERVTHDGC---CCSKRVVTAPVVNASVLKLG 1830
Query 1779 FKKGVQIPCTCGKQATKYLVQQESPFVMM-SAPPA---QYELKHGTFTCASEYTGNYQCG 1834
+ G+ C G +V + +++ P + G GN G
Sbjct 1831 VEDGL---CPHGLNYIGKVVVVKGTTIVVNVGKPVVAPSHLFLKGVSYTTFLDNGNGVVG 1887
Query 1835 HYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPV 1880
HY + DG P+T+V E + PV
Sbjct 1888 HYTVFDHGTGM-VHDGDAFVPGDLNVSPVTNVVVSEQTAVVIKDPV 1932
Score = 164 bits (414), Expect = 4e-38, Method: Composition-based stats.
Identities = 69/277 (25%), Positives = 106/277 (38%), Gaps = 19/277 (7%)
Query 993 GSEDNQTTTIQTIVEVQPQLEMELTPVVQTIE---VNSFSGYLKLTDNVYIKNADIVEEA 1049
G + T+ TI L P V ++ V F Y NV D +
Sbjct 1255 GRHQIKYDTLNTICVKDVNWTAPLVPAVDSVVEPVVKPFYSY----KNVDFYQGDFSDLV 1310
Query 1050 KKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHN 1109
K + VVNAAN L HGGG+A A++ T +Q S+DYI +GP+KVG +L
Sbjct 1311 K-LPCDFVVNAANEKLSHGGGIAKAIDVYTKGMLQKCSNDYIKAHGPIKVGRGVMLEA-- 1367
Query 1110 LAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTV 1169
L +VVGP K L+K+ F V L PL+S GIF SL + V
Sbjct 1368 LGLKVFNVVGPRKGKHAPELLVKAYKSVFANSGVALTPLISVGIFSVPLEESLSAFLACV 1427
Query 1170 -RTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPS---VEQR 1225
+ + + ++ + E + P +E +++ R
Sbjct 1428 GDRHCKCFCYGDKEREAIIKYMDGLVDAIFKEALVDTTPVQEDVQQVSQKPVLPNFEPFR 1487
Query 1226 KQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGN 1262
+ C E +L + L+L+ + N +
Sbjct 1488 IEGAHAFYECNPEGLMSLG-----ADKLVLFTNSNLD 1519
Score = 70.9 bits (172), Expect = 6e-10, Method: Composition-based stats.
Identities = 73/427 (17%), Positives = 125/427 (29%), Gaps = 66/427 (15%)
Query 172 ELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCC 231
EL GG VD CG DG P+ + + T F D++ G
Sbjct 102 ELTFGRRGGNIVP-VDQYMCGADGKPV-------LQESEWEYTDF----FADSEDGQLNI 149
Query 232 REHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKK 291
+ AW ERS+ SY Q IK T+ F + +K + KK
Sbjct 150 AGITYVKAWIVERSDVSYASQNLTSIKSITYCSTYE-----HTFLDGTAMKVARTPKIKK 204
Query 292 K------LDGFMGRIRSVYPVASPNECN----QMCLSTLMKCDHCGETSWQTGDFVKATC 341
L I S + + + + L +KC CG W GD+
Sbjct 205 NVVLSEPLATIYREIGSPFVDNGSDARSIIRRPVFLHAFVKCK-CGSYHWTVGDWTSYVS 263
Query 342 EFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGG 401
CG + +C +P + VV T G
Sbjct 264 TCCGFK-CKPVLVASCSAMPGSVVV----------------------------TRAGAGT 294
Query 402 RTIAFGGCVFSYVGCHNKCAYW-VPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVN 460
+ +V + A+W + + + +G E E + L +
Sbjct 295 GVKYYNNMFLRHVADIDGLAFWRILKVQSKDDLACSGKFLEHHEEGFTDPCYFLNDSSLA 354
Query 461 INIVGDFK----LNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKA 516
+ D +E I+A SA V+ V D + G+ +
Sbjct 355 TKLKFDILSGKFSDEVKQAIIAGHVVVGSALVDIVD--DALGQPWFIRKLGD--LASAPW 410
Query 517 KKGAWNIGEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQY 576
++ + + + F + SI + E + L A ++ ++++
Sbjct 411 EQLKAVVRGLGLLSDEVVLFGKRLSCATLSIVNGVFEFLADVPEKLAAAVTVFVNFLNEF 470
Query 577 SLRLIDA 583
D
Sbjct 471 FESACDC 477
Score = 64.7 bits (156), Expect = 4e-08, Method: Composition-based stats.
Identities = 62/339 (18%), Positives = 111/339 (33%), Gaps = 37/339 (11%)
Query 1503 ETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLLSL 1562
I + G W + + IE LK + P + D E T NL ++S
Sbjct 936 NRIKVTGG---WDDVVEYINVAIEVLKD------HVEVPKYYIYDEEGGTDPNLPVMVSQ 986
Query 1563 REVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDG-ADVTKIKPHNSHEGKTFYVL 1621
+ + + D +++ + G + + + ADV +P + +G
Sbjct 987 WPLNDDTI--SQDLLDVEVVTDAPIDSEGDEVDSSAPEKVADVANSEPGD--DGLPVAPE 1042
Query 1622 PNDDTL-RVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATAL 1680
N ++ A D + + + GL ++ + NNC++ + L
Sbjct 1043 TNVESEVEEVAATLSFIKDTPS-----TVTKDPFAFDFVSYGGLKVLRQSHNNCWVTSTL 1097
Query 1681 LTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHAN 1740
+ LQ + + +P A AG +G LGDV + L + +
Sbjct 1098 VQLQLLGIVDDP-----AMELFSAGRVGPMVRKCYESQKAILGSLGDVSACLESLTK--D 1150
Query 1741 LDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQ 1800
L + K +VVC CG + +G + T + E F C +
Sbjct 1151 LHTLKITCSVVCG-CGTGERIYEG---CAFRMTPTLEPF--PYGACAQCAQVLMHTFKSI 1204
Query 1801 ESPFVMMSAPPAQYELKHGTFT--CASEYTGNYQCGHYK 1837
+ A L CA+ + G GHY
Sbjct 1205 VGTGIFCRDTTALS-LDSLVVKPLCAAAFIGK-DSGHYV 1241
>sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus
NL63 OX=277944 GN=1a PE=1 SV=1
Length=4060
Score = 2572 bits (6667), Expect = 0.0, Method: Composition-based stats.
Identities = 754/2306 (33%), Positives = 1180/2306 (51%), Gaps = 121/2306 (5%)
Query 2110 PNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYM 2169
++LS + + G N TI + ++K+ + N +
Sbjct 1855 SSDLSTLAVTAIVVVGGCVTSN---VPTIVSEKISVMDKLDTGAQKFFQ--FGDFVMNNI 1909
Query 2170 PYFFTLLLQLCTFTRST----NSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSK 2225
F T LL + + R++ + ++ A P +S K+ + ++ +K
Sbjct 1910 VLFLTWLLSMFSLLRTSIMKHDIKVIAKAPKRTGVILTRS-FKYNIRSALFVIKQK---- 1964
Query 2226 LINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGS 2285
+I+ L L ++ + C GY ST YC S
Sbjct 1965 -WCVIV--TLFKFLLLLYAIYALVFMIVQFSPFNSLLCGDIVSGYEKST-FNKDIYCGNS 2020
Query 2286 IPCSVCLSGLDSLDTYPSLETIQITISSF-KWDLTAFGLVAEWFLAYILFTRFFYVLGLA 2344
+ C +CL + + I L F ++ + ++ RF + +A
Sbjct 2021 MVCKMCLFSYQEFNDLDHTSLVWKHIRDPILISLQPFVILVILLIFGNMYLRFGLLYFVA 2080
Query 2345 AIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGC 2404
+ F S+ H W + P + ++ + H++ GC
Sbjct 2081 QFISTFGSFLGFH--QKQWFLHF-------VPFDVLCNEFLATFIVCKIVLFVRHIIVGC 2131
Query 2405 NSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTF 2464
N++ C+ C K R RV TI+NG+ +SFYV ANGG FC HN+ CVNCD+F G+TF
Sbjct 2132 NNADCVACSKSARLKRVPLQTIINGMHKSFYVNANGGTCFCNKHNFFCVNCDSFGPGNTF 2191
Query 2465 ISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNL 2524
I+ ++AR+L K + PT + I+D V NG LY + + S +
Sbjct 2192 INGDIARELGNVVKTAVQPTAPAYVIIDKVDFVNGFYRLYSGDTFWRYDFDITESKYSCK 2251
Query 2525 DNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSA 2584
+ L+ N N IV+ S + K+A VY+SQL+C+PI L++ L+S + S
Sbjct 2252 EVLKNCNV----LENFIVY-NNSGSNITQIKNACVYFSQLLCEPIKLVNSELLSTL--SV 2304
Query 2585 EVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDS 2644
+ + AYV+ ++F ++L ++ AE + ++
Sbjct 2305 DFNGVLHKAYVDVLCNSF---FKELTANMSMAECKATLGLT------------------- 2342
Query 2645 DVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKV-ENMTPRDLGACIDCSARHINAQV 2703
V D V + +H+ D+ ++ S NN+ ++Y K + ++ D+ C+ ++ +N V
Sbjct 2343 -VSDDDFVSAVANAHRYDVLLSDLSFNNFFISYAKPEDKLSVYDIACCMRAGSKVVNHNV 2401
Query 2704 AKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGG 2763
+I ++W VKDF +LS++ +K + K L F LT + + V T I K G
Sbjct 2402 LIKESIPIVWGVKDFNTLSQEGKKYLVKTTKAKGLTFLLTFNDNQAITQVPATSIVAKQG 2461
Query 2764 KIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIAST 2823
+ + V LFV A+F ++ + + T F +K I+ G + +
Sbjct 2462 AGFK---RTYNFLWYVCLFVVALFIGVSFIDYTTTVTSF--HGYDFKYIENGQLKVFEAP 2516
Query 2824 DTCFANKHADFDTWFSQRGGSYT-NDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFL 2882
C N +F+ W + G T N CP++ V R VVPG+P + G L
Sbjct 2517 LHCVRNVFDNFNQWHEAKFGVVTTNSDKCPIVVGVSERI--NVVPGVPTNVYLV--GKTL 2572
Query 2883 HFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGS 2942
F + +CY + C+ + CT + G V YCY+T+++EGS
Sbjct 2573 VFTLQAAFGNTGVCYDFDGVTTSD-----KCIFNSACTRLEGLGGDNV-YCYNTDLIEGS 2626
Query 2943 VAYESLRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDSEYCRHGTCERSEAGVCVSTS 3001
Y +L+P+ Y + ++FP G +R + T + YCR G C S GVC
Sbjct 2627 KPYSTLQPNAYYKYDAKNYVRFPEILARGFGLRTIRTLATRYCRVGECRDSHKGVCFGFD 2686
Query 3002 GRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLA 3061
+W +N+ R G CG ++LL N+ + + +S ++ + A +T L
Sbjct 2687 -KWYVNDG--RVDDGYICGDGLIDLLVNVLSIFSSSFSVVAMSGHMLFNFLFAAFITFLC 2743
Query 3062 YYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVS 3121
+ +F+R FG+ S+ V L++ +T F +Y+++Y F T +
Sbjct 2744 FLVTKFKRVFGDLSYGVFTVVCATLINNISYVVTQ-NLFFMLLYAILYF--VFTRTVRYA 2800
Query 3122 FLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRV---VFNGVSF-STFEE 3177
++ HI ++V + L+P+W+ + S F N K ++ +F G F TFE
Sbjct 2801 WIWHIAYIVAYFLLIPWWLLTWF----SFAAFLELLPNVFKLKISTQLFEGDKFIGTFES 2856
Query 3178 AALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKA 3237
AA TF+L+ Y +L + + + Y A YNKYKY+SG+ YR A HLAKA
Sbjct 2857 AAAGTFVLDMRSYERLINTI--SPEKLKNYAASYNKYKYYSGSASEADYRCACYAHLAKA 2914
Query 3238 LNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD 3297
+ D++ +D+LY PP S S LQSG +KMA PSG VE C+V+V G+T LNG+WL D
Sbjct 2915 MLDYAKDHNDMLYSPPTISYNST-LQSGLKKMAQPSGCVERCVVRVCYGSTVLNGVWLGD 2973
Query 3298 VVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTA 3357
V CPRHVI S +L +Y+ HNF V V L V+G +M VL++KV +
Sbjct 2974 TVTCPRHVIAPSTTVL-IDYDHAYSTMRLHNFSVSHNGVFLGVVGVTMHGSVLRIKVSQS 3032
Query 3358 NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDY 3417
N TPK+ F ++PG +F++LACY G SGV+ +R NFTIKGSF+NG+CGS G+N+
Sbjct 3033 NVHTPKHVFKTLKPGDSFNILACYEGIASGVFGVNLRTNFTIKGSFINGACGSPGYNVRN 3092
Query 3418 -DCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVI 3476
V FCY+H +EL +G H G+D G+ YG F D+ + Q + ++ NV+A+LYAA++
Sbjct 3093 DGTVEFCYLHQIELGSGAHVGSDFTGSVYGNFDDQPSLQVESANLMLSDNVVAFLYAALL 3152
Query 3477 NGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQ 3536
NG RW+L ++ FN AM Y ++ V+ L+A+TG++V + AS++ L
Sbjct 3153 NGCRWWLCSTRVNVDGFNEWAMANGYTSVSS--VECYSILAAKTGVSVEQLLASIQHL-H 3209
Query 3537 NGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQ 3596
G G+ ILG + L DEFT +VV+Q GV QS + I G L ++ ++
Sbjct 3210 EGFGGKNILGYSSLCDEFTLAEVVKQMYGVNLQSG--KVIFGLKTMFLFSVFFTMFWAEL 3267
Query 3597 STQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMP 3656
++ ++ P ++ +S MF+KHK FL +FLLP++ A +N V
Sbjct 3268 FI-YTNTIWINPVILTPIFCLLLFLSLVLTMFLKHKFLFLQVFLLPTVIATALYNCVL-- 3324
Query 3657 ASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLT 3716
++++ + + S+ ++ V + ++ L T R + + +++
Sbjct 3325 DYYIVKFLADHFNYNVSVLQMDVQGLVNVLVCLFVVFLHTWRFSKERFTHWFTYVCSLIA 3384
Query 3717 LVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTL 3776
+ Y +Y +S+ + + S+ + V L+R IVF E F +
Sbjct 3385 VAYTYFYSGDF---LSLLVMFLCAISSDWYIGAIVFRLSRLIVFFSPE---SVFSVFGDV 3438
Query 3777 QCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSID 3836
+ ++VY GY Y+G+ NR+F+ T+GVYD+ VS EF+YM + GL P D
Sbjct 3439 KLTLVVYLICGYLVCTYWGILYWFNRFFKCTMGVYDFKVSAAEFKYMVANGLHAPHGPFD 3498
Query 3837 AFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHN 3896
A L+ KLLG+GG CIK++TVQSK++D+KCT+VVLL L + + ++S WA CV LHN
Sbjct 3499 ALWLSFKLLGIGGDRCIKISTVQSKLTDLKCTNVVLLGCLSSMNIAANSSEWAYCVDLHN 3558
Query 3897 DILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAA 3956
I L D +A +++LL+ LS ++ L + DN +TLQ++AS F S+PSY A
Sbjct 3559 KINLCDDPEKAQSMLLALLAFFLSKHSDFGLDGLIDSYFDNSSTLQSVASSFVSMPSYIA 3618
Query 3957 FATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQA 4016
+ A++AYE A+ANG S ++K+LK+++N+AKSEFD + ++Q+K+ +MA+QA TQMYK+A
Sbjct 3619 YENARQAYEDAIANGSSSQLIKQLKRAMNIAKSEFDHEISVQKKINRMAEQAATQMYKEA 3678
Query 4017 RSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPD 4076
RS ++++KV SAM ++LF MLR+LD ++ ++N ARDG VPL++IP T+A+KL +V PD
Sbjct 3679 RSVNRKSKVISAMHSLLFGMLRRLDMSSVETVLNLARDGVVPLSVIPATSASKLTIVSPD 3738
Query 4077 YNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSA 4136
+Y + YA +W + V D D + V + EI+ +N L WPLI+ R
Sbjct 3739 LESYSKIVCDGSVHYAGVVWTLNDVKDNDGRPVHVKEITKENVETLTWPLILNCER---V 3795
Query 4137 VKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARF 4196
VKLQNNE+ P L+Q A D NAL YNT G F+ A +S+ DLK+ ++
Sbjct 3796 VKLQNNEIMPGKLKQKPMKAEGDGGVLGDGNAL--YNTEGGKTFMYAYISNKADLKFVKW 3853
Query 4197 PKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGN 4256
G TI EL+ PCRF+ +TP GP+VKYLYF+K LN L RG VLG + AT+RLQAG
Sbjct 3854 EYEGGCNTI--ELDSPCRFMVETPNGPQVKYLYFVKNLNTLRRGAVLGFIGATIRLQAGK 3911
Query 4257 ATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANM 4316
TE+ NS +L+ CAF+VD A Y + + G +P++NC+KML G GQAIT + +AN
Sbjct 3912 QTELAVNSGLLTACAFSVDPATTYLEAVKHGAKPVSNCIKMLSNGAGNGQAITTSVDANT 3971
Query 4317 DQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMW 4376
+Q+S+GGAS CLYCR H+ HP+ G+C KGK VQ+P C DP+ F L+N VC VCG W
Sbjct 3972 NQDSYGGASICLYCRAHVPHPSMDGYCKFKGKCVQVPIGCL-DPIRFCLENNVCNVCGCW 4030
Query 4377 KGYGCSCDQLREPMLQSADAQSFLNR 4402
G+GC+CD+ +QS D S+LN
Sbjct 4031 LGHGCACDR---TTIQSVDI-SYLNE 4052
Score = 173 bits (439), Expect = 6e-41, Method: Composition-based stats.
Identities = 69/340 (20%), Positives = 123/340 (36%), Gaps = 34/340 (10%)
Query 1544 FHLDGEVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGAD 1603
F ++ V+ ++ + + + T D IN+ VV+ S + G+Q G DG D
Sbjct 1564 FVVESNVMDVNDC------FKNDNVVLKITEDGINVKDVVVESSKSLGKQLGVVS-DGVD 1616
Query 1604 VTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQ--V 1661
S EG + N DT+ A E F + A K + YP V
Sbjct 1617 --------SFEGV---LPINTDTVLSVAPEVDWVAFYGFEKAALFASLDVKPYGYPNDFV 1665
Query 1662 NGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKT 1721
G + DNNC++ + LQ ++ F L + + G+ F + I +
Sbjct 1666 GGFRVLGTTDNNCWVNATCIILQYLKPTFKSKGLNVLWNKFVTGDVGPFVSFIYFITMSS 1725
Query 1722 VGELGDVRETMSYLFQHANLDS-CKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFK 1780
G+ GD E +S L ++ DS C C ++T+ V++ + ++ +
Sbjct 1726 KGQKGDAEEALSKLSEYLISDSIVTLEQYSTCDIC---KSTVVEVKSAIVCASVLKDGCD 1782
Query 1781 KGVQIPCTCGKQATKYLVQQESPFVMMSA----PPAQYELKHGTFTCASEYTGNYQCGHY 1836
G C + + V+ + +L +G ++G++ GHY
Sbjct 1783 VGF---CPHRHKLRSRVKFVNGRVVITNVGEPIISQPSKLLNGIAYT--TFSGSFDNGHY 1837
Query 1837 KHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTT 1876
+ DGA L S +T + T+
Sbjct 1838 V-VYDAANNAVYDGARLFSSDLSTLAVTAIVVVGGCVTSN 1876
Score = 159 bits (402), Expect = 1e-36, Method: Composition-based stats.
Identities = 78/309 (25%), Positives = 126/309 (41%), Gaps = 27/309 (9%)
Query 993 GSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKV 1052
G D + +++ T+ V + ++ EV F+ Y NV DI V
Sbjct 1228 GVFDIKNSSVNTVCFVDVDFH---SVEIEAGEVKPFAVY----KNVKFYLGDISHLVNCV 1280
Query 1053 KPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAK 1112
VVNAAN L HGGGVA A++ T +Q S DYI++NGPLKVG +L
Sbjct 1281 SFDFVVNAANENLLHGGGVARAIDILTEGQLQSLSKDYISSNGPLKVGAGVMLECEKF-- 1338
Query 1113 HCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTN 1172
+ +VVGP K E L+++ ++ + L PLLS GIFG +SL+
Sbjct 1339 NVFNVVGPRTGKHEHSLLVEAYNSILFENGIPLMPLLSCGIFGVRIENSLKALFSC---- 1394
Query 1173 VYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKI 1232
+K + F+ +E+Q K + ++ P I + R + +
Sbjct 1395 ---------DINKPLQVFVYSSNEEQAVLKF--LDGLDLTPVIDDVDVVKPFRVEGNFSF 1443
Query 1233 KACVEEVTTTLEETKFLTENLLLYIDINGNLHPDS-ATLVSDIDITFLKKDAPYIVGDVV 1291
C + L N +L +D G L ++ + +L G++V
Sbjct 1444 FDCGVNALDG--DIYLLFTNSILMLDKQGQLLDTKLNGILQQAALDYLATVKTVPAGNLV 1501
Query 1292 QEGVLTAVV 1300
+ V + +
Sbjct 1502 KLFVESCTI 1510
Score = 69.7 bits (169), Expect = 1e-09, Method: Composition-based stats.
Identities = 43/192 (22%), Positives = 77/192 (40%), Gaps = 15/192 (8%)
Query 1648 SALNHTKKWKYPQVN--GLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAG 1705
L+ + + + + G+ + +DNNC+++T L+ LQ +L + +Q + G
Sbjct 1034 HVLSIKQPFSFSFRDELGVRVLDQSDNNCWISTTLVQLQLTKLLDDSIEMQL----FKVG 1089
Query 1706 EAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGV 1765
+ + + G LGD + +S L + +C + C CG++ G
Sbjct 1090 KVDSIVQKCYELSHLISGSLGDSGKLLSELLK--EKYTCSITFEMSCD-CGKKFDDQVG- 1145
Query 1766 EAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAP-PAQYELKHGTFTCA 1824
++ + F+KG C C K T LV + V + P P + C+
Sbjct 1146 --CLFWIMPYTKLFQKG--ECCICHKMQTYKLVSMKGTGVFVQDPAPIDIDAFPVKPICS 1201
Query 1825 SEYTGNYQCGHY 1836
S Y G GHY
Sbjct 1202 SVYLGVKGSGHY 1213
Score = 65.9 bits (159), Expect = 2e-08, Method: Composition-based stats.
Identities = 71/544 (13%), Positives = 146/544 (27%), Gaps = 82/544 (15%)
Query 153 PYEDFQENWNTKHSSGVTRELMREL-----NGGAYTRYVDNNFCGPDGYPLECIKDLLAR 207
P+ D N + ++++ +G +VD CG DG P+
Sbjct 77 PFSDRPLNLRGWLIFSNSNYVLQDFDVVFGHGAGSVVFVDKYMCGFDGKPVLP------- 129
Query 208 AGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFN 267
+ E D+ + +++AW R + SYE Q I+ T
Sbjct 130 -----KNMWEFRDYFNNNTDSIVIGGVTYQLAWDVIRKDLSYEQQNVLAIESIHYLGTT- 183
Query 268 GECPNFVFPLNSIIKTIQP---RVEKKKLDGFMGRIRSVYPVASPNE-------CNQMCL 317
+ +P + + R+ N +
Sbjct 184 ----GHTLKSGCKLTNAKPPKYSSKVVLSGEWNAVYRAFGSPFITNGMSLLDIIVKPVFF 239
Query 318 STLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNSE 377
+ +KC+ CG SW G C K +P + ++ C
Sbjct 240 NAFVKCN-CGSESWSVG-AWDGYLSSCCGTPAKKLCVVPGNVVPGDVIITSTSAGCG--- 294
Query 378 VGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTG 437
+ G V ++ + W + H+
Sbjct 295 -------------------------VKYYAGLVVKHITNITGVSLW------RVTAVHSD 323
Query 438 VVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLD-- 495
+ S D LL + + V N+ L + F + +D
Sbjct 324 GMFVAS-SSYDALLHRNSLDPFCFD-VNTLLSNQLRLAFLGASVTEDVKFAASTGVIDIS 381
Query 496 ---YKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSIFSRTL 552
+ + I+ + + V K A + + + R V+SI S L
Sbjct 382 AGMFGLYDDILTNNKPWFVRKASGLFDAI-WDAFVAAIKLVPTTTGVLVRFVKSIASTVL 440
Query 553 ETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLV------VMAYITGGVV 606
+ + + ++ + A F+ D+ V +V
Sbjct 441 TVSNGVIIMCADVPDAFQSVYRTFTQAICAAFDFSLDVFKIGDVKFKRLGDYVLTENALV 500
Query 607 QLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVT 666
+LT++ + + +K + + + ++ + G+IV
Sbjct 501 RLTTEVVRGVRDARIKKAMFTKVVVGPTTEVKFSVIELATVNLRLVDCAPVVCPKGKIVV 560
Query 667 CAKE 670
A +
Sbjct 561 IAGQ 564
Score = 38.1 bits (87), Expect = 4.3, Method: Composition-based stats.
Identities = 60/340 (18%), Positives = 112/340 (33%), Gaps = 36/340 (11%)
Query 637 EGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIG 696
E F+ D + +K T G + CAK + + + N FL
Sbjct 732 EKFNFVTDWLKTLKLTLTS-----NGLLGNCAKRFRRVLVKLLDVYNGFLETVCSVAYTA 786
Query 697 GAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEV 756
G +K + +V S + R V RE + P + + +T +
Sbjct 787 GVCIKYYAVNVPYVVISGFVSR--VIRRERCDMTFPCVSCVTFFYEFLDTCFGVSKPNAI 844
Query 757 VLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLK 816
++ +L ++ P G ++G L + D Y A V FT
Sbjct 845 DVEHLEL---KETVFVE---PKDGGQFFVSGDYLWYVVDDIYYPASCNG--VLPVAFTKL 896
Query 817 GGAPTKVTFGDDT-VIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVV 875
G K++F DD V +V+ V + FE ++ + L +K ++ + V+
Sbjct 897 AGG--KISFSDDVIVHDVEPTHKVKLIFEFEDDVVTSLCKKSFGKSIIYTGDWEGLHEVL 954
Query 876 ADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGD 935
A + + + +Y++DE G + ++ + S +P D
Sbjct 955 TSA--------------MNVIGQHIKLPQFYIYDEEGGYDVSKPVMISQWPISNDSNGCV 1000
Query 936 CEEEEF----EPSTQYEYGTEDDYQGKPLEFGATSAALQP 971
E E E D +P E +++
Sbjct 1001 VEASTDFHQLECIVDDSVREEVDIIEQPFEEVEHVLSIKQ 1040
>sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=1a PE=1 SV=1
Length=4017
Score = 2548 bits (6604), Expect = 0.0, Method: Composition-based stats.
Identities = 725/2294 (32%), Positives = 1142/2294 (50%), Gaps = 150/2294 (7%)
Query 2156 IVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASF 2215
+ + R+ Y L T+ ++K P K+ V
Sbjct 1830 MAGDKILRLLLEVFKYLLVL-FMCLRSTKMPKVKVK---PPLAFKDFGAKVRTL------ 1879
Query 2216 NYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTN 2275
NY++ N + LLL + + + Y ++ V+ C G + Y NS+
Sbjct 1880 NYMRQLNKPSVWRYAKLVLLL-IAIYNFFYLFVSIPVVHK-----LTCNGAVQAYKNSS- 1932
Query 2276 VTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWD----LTAFGLVAEWFLAY 2331
+ C SI C CL+ D L + L+ S W+ L+ F +A + Y
Sbjct 1933 FIKSAVCGNSILCKACLASYDELADFQHLQVTWDFKSDPLWNRLVQLSYFAFLAVFGNNY 1992
Query 2332 ILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFY 2391
+ R F + ++ + L+ SYF ++ SW + ++V ISA + +
Sbjct 1993 V---RCFLMYFVSQYLNLWLSYFG--YVEYSWFL----HVVNFESISAEFVIVVIVVKAV 2043
Query 2392 YVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWN 2451
K H+V C++ +C C + R TR+ +VNG ++ YV+ANG FCK HN+
Sbjct 2044 LALK---HIVFACSNPSCKTCSRTARQTRIPIQVVVNGSMKTVYVHANGTGKFCKKHNFY 2100
Query 2452 CVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLY------- 2504
C NCD++ +TFI DE+ RDLS K+ + TD+S V V +G Y
Sbjct 2101 CKNCDSYGFENTFICDEIVRDLSNSVKQTVYATDRSHQEVTKVECSDGFYRFYVGDEFTS 2160
Query 2505 --FDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYS 2562
+D +K + L + LD+ + GS NV ++A VY+S
Sbjct 2161 YDYDVKHKKYSSQEVLKSMLLLDDFIVYSPSGSALANV--------------RNACVYFS 2206
Query 2563 QLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAK 2622
QL+ +PI +++ L+ D+ S + +F+A N ++FNV + + K L E +
Sbjct 2207 QLIGKPIKIVNSDLLEDL--SVDFKGALFNAKKNVIKNSFNVDVSECKNL-----DECYR 2259
Query 2623 NVSLDNVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKV-- 2680
+L+ STF A +H+ I +T S NN+ + K
Sbjct 2260 ACNLNVSFSTFEMAVNN------------------AHRFGILITDRSFNNFWPSKVKPGS 2301
Query 2681 ENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPF 2740
++ D+G C+ A+ +NA+V +++W +DF +LS +K + + + F
Sbjct 2302 SGVSAMDIGKCMTSDAKIVNAKVLTQRGKSVVWLSQDFAALSSTAQKVLVKTFVEEGVNF 2361
Query 2741 KLTCATTRQVVNVV----TTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVM 2796
LT ++ T ++ K G + + QL ++ ++ I L + V
Sbjct 2362 SLTFNAVGSDDDLPYERFTESVSPKSGSGFFDVITQLKQIVILVFVFIFICGLCSVYSVA 2421
Query 2797 SKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGS-YTNDKACPLIA 2855
++ S+E Y I G+ + T +C N + F WF + G T K+CP++
Sbjct 2422 TQSYIESAEGYDYMVIKNGIVQPFDDTISCVHNTYKGFGDWFKAKYGFIPTFGKSCPIVV 2481
Query 2856 A-VITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACV 2914
V E +P +P + G L F V N+CY + D CV
Sbjct 2482 GTVFDLENMRPIPDVPAYVSIV--GRSLVFAINAAFGVTNMCYDHTGNAVSKDSYFDTCV 2539
Query 2915 LAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVR 2974
CT G V YC ++EG+ Y L PD Y G++++ P +R
Sbjct 2540 FNTACTTLTGLGGTIV-YCAKQGLVEGAKLYSDLMPDYYYEHASGNMVKLPAIIRGLGLR 2598
Query 2975 VVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPL 3034
V T + YCR G C S+AG C +V +N++ G CG + N+F
Sbjct 2599 FVKTQATTYCRVGECIDSKAGFCFGGDNWFVYDNEFGN---GYICGNSVLGFFKNVFKLF 2655
Query 3035 IQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCL 3094
+ + S +++ I+A + + Y ++F++ FG+ + ++ + +++ +
Sbjct 2656 NSNMSVVATSGAMLVNIIIACLAIAMCYGVLKFKKIFGDCTFLIVMIIVTLVVNNVSYFV 2715
Query 3095 TPVYSFLPGVYSVIYLYLTFYLTNDVSF--LAHIQWMVMFTPLVPFWITIAYIICISTKH 3152
T + +IY + +++T +++ + +++ + + P+++ AYI+
Sbjct 2716 TQ-----NTFFMIIYAIVYYFITRKLAYPGILDAGFIIAYINMAPWYVITAYILVF---- 2766
Query 3153 FYWFFSNYLKRRV---VFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYL 3208
Y + K +V +F G F FE AA+ TF+++ Y + + + + Y
Sbjct 2767 LYDSLPSLFKLKVSTNLFEGDKFVGNFESAAMGTFVIDMRSYETIVNST--SIARIKSYA 2824
Query 3209 ALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRK 3268
+NKYKY++G+M YR A HL KAL D+S + +D+LY PP S+ S LQSG RK
Sbjct 2825 NSFNKYKYYTGSMGEADYRMACYAHLGKALMDYSVNRTDMLYTPPTVSVNST-LQSGLRK 2883
Query 3269 MAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHN 3328
MA PSG VE C+V+V+ G LNGLWL D V CPRHVI S+ NYE+ + HN
Sbjct 2884 MAQPSGLVEPCIVRVSYGNNVLNGLWLGDEVICPRHVIA-SDTTRVINYENEMSSVRLHN 2942
Query 3329 FLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGV 3388
F V NV L V+ + L LKV+ NP TP++KF I+ G++F++LACY G P V
Sbjct 2943 FSVSKNNVFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIKAGESFNILACYEGCPGSV 3002
Query 3389 YQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPF 3448
Y MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++ EG YG +
Sbjct 3003 YGVNMRSQGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLELGNGSHVGSNFEGEMYGGY 3062
Query 3449 VDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQD 3508
D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + +L +N A ++ L+
Sbjct 3063 EDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSLESYNTWAKTNSFTELSS- 3121
Query 3509 HVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTF 3568
D L+A+TG +V + S+ L G GRTIL L DEFTP +V+RQ GV
Sbjct 3122 -TDAFSMLAAKTGQSVEKLLDSIVRL-NKGFGGRTILSYGSLCDEFTPTEVIRQMYGVNL 3179
Query 3569 QSAVKRTIKGTHHWLLLTILTSLLVLVQS----TQWSLFFFLYENAFLPFAMGIIAMSAF 3624
Q+ ++ I+T++ +L ++ F ++ +S
Sbjct 3180 QAGKVKS-------FFYPIMTAMTILFAFWLEFFMYTPFTWINPTFVSIVLAVTTLISTV 3232
Query 3625 AMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
+ +KHK F F+LPS+ V N+ + S+ + + ++ +T ++ ++
Sbjct 3233 FVSGIKHKMLFFMSFVLPSVILVTAHNL-FWDFSYYESLQSIVENTNTMFLPVDMQGVML 3291
Query 3685 YASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQA----------ISMW 3734
++ + + R + + +L + V D+ ++M
Sbjct 3292 TVFCFIVFVTYSVRFFTCKQSWFSLAVTTILVIFNMVKIFGTSDEPWTENQIAFCFVNML 3351
Query 3735 ALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYF 3794
+I+S+T+ VV +A IV + F ++CI +VY GY CY+
Sbjct 3352 TMIVSLTTKDWMVVIASYRIAYYIVVCVM--PSAFVSDFGFMKCISIVYMACGYLFCCYY 3409
Query 3795 GLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIK 3854
G+ +NR+ +T GVY + VS E +YM + L PKN+ DA L+ KL+GVGGK IK
Sbjct 3410 GILYWVNRFTCMTCGVYQFTVSAAELKYMTANNLSAPKNAYDAMILSAKLIGVGGKRNIK 3469
Query 3855 VATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSL 3914
++TVQSK++++KCT+VVLL +L ++ VES+SK W CV LHN+I L D EK+++L
Sbjct 3470 ISTVQSKLTEMKCTNVVLLGLLSKMHVESNSKEWNYCVGLHNEINLCDDPEIVLEKLLAL 3529
Query 3915 LSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSE 3974
++ LS D+++L E +N LQ++AS +++LPS+ A A+ E+A N S
Sbjct 3530 IAFFLSKHNTCDLSELIESYFENTTILQSVASAYAALPSWIALEKARADLEEAKKNDVSP 3589
Query 3975 VVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLF 4034
+LK+L K+ N+AKS+F+R+A++Q+KL+KMA+QA MYK+AR+ D+++K+ SAM ++LF
Sbjct 3590 QILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLF 3649
Query 4035 TMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASA 4094
ML+KLD ++N II+ AR+G +PL+IIP +A +L+V+ P + YA A
Sbjct 3650 GMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATRLVVITPSLEVFSKIRQENNVHYAGA 3709
Query 4095 LWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSC 4154
+W I +V DA+ V L E++ N NL WPL +T R KLQNNE+ P L++ +
Sbjct 3710 IWTIVEVKDANGSHVHLKEVTAANELNLTWPLSITCERT---TKLQNNEIMPGKLKERAV 3766
Query 4155 AAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCR 4214
A T + A + G F+ A ++ +LK+ ++ + I ELE P R
Sbjct 3767 RASATLDGEAFGSGKALMASESGKSFMYAFIASDNNLKYVKWESN--NDIIPIELEAPLR 3824
Query 4215 FVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAV 4274
F D GP+VKYLYF+K LN L RG VLG + ATVRLQAG TE P+NS++L+ CAF+
Sbjct 3825 FYVDGANGPEVKYLYFVKNLNTLRRGAVLGYIGATVRLQAGKPTEHPSNSSLLTLCAFSP 3884
Query 4275 DAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHI 4334
D AKAY D + G QP+ NCVKML G G A+T EAN Q+S+GGAS C+YCRCH+
Sbjct 3885 DPAKAYVDAVKRGMQPVNNCVKMLSNGAGNGMAVTNGVEANTQQDSYGGASVCIYCRCHV 3944
Query 4335 DHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA 4394
+HP G C KGK+VQIPT DP+ F ++N VC VCG W GC CD R M
Sbjct 3945 EHPAIDGLCRYKGKFVQIPTG-TQDPIRFCIENEVCVVCGCWLNNGCMCD--RTSMQSFT 4001
Query 4395 DAQSFLNRVCGVSA 4408
QS+LN CGV
Sbjct 4002 VDQSYLNE-CGVLV 4014
Score = 205 bits (521), Expect = 1e-50, Method: Composition-based stats.
Identities = 82/409 (20%), Positives = 147/409 (36%), Gaps = 46/409 (11%)
Query 874 VVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKL--------ASHMYCSFY 925
+V + + L P+ E G+ D + T G
Sbjct 1171 IVLERAVFKLTPLKESF-NYGVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVK 1229
Query 926 PPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEE---EQEEDWLDD 982
P G + + D KPL+ ++ L + E +
Sbjct 1230 PVMHAVYTGTTQNGHYMVDDIEHGYCVDGMGIKPLKKRCYTSTLFINANVMTRAEKPKQE 1289
Query 983 DSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKN 1042
+ V QQ E+N+++ + ++ P+ + + P + +++ + G L + N
Sbjct 1290 FKVEKVEQQPIVEENKSSIEKEEIQ-SPKNDDLILPFYKAGKLSFYQGALDVLINF---- 1344
Query 1043 ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGS 1102
++P V+VNAAN LKH GGVA A++ T + S DY+ N + G +
Sbjct 1345 ---------LEPDVIVNAANGDLKHMGGVARAIDVFTGGKLTERSKDYLKKNKSIAPGNA 1395
Query 1103 CVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQH-EVLLAPLLSAGIFGADPIHS 1161
L+ VGP L + Y+ + +L PL+S GIF
Sbjct 1396 VFFENVIEHLSVLNAVGPRNGDSRVEAKLCNVYKAIAKCEGKILTPLISVGIF------- 1448
Query 1162 LRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKI--AEIPKEEVKPFITESK 1219
VR L K + D+ ++ F+ E+Q + IP + + +
Sbjct 1449 ------NVRLETSLQCLLKTVNDRGLNVFVYTDQERQTIENFFSCSIPVNVTEDNVNHER 1502
Query 1220 PSVEQRKQDDKKIKACV----EEVTTTLEETKFLTENLLLYIDINGNLH 1264
SV K +++K V ++VT L + + ++ IDI+ H
Sbjct 1503 VSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAFDVGQKVIKAIDIDWQAH 1551
Score = 173 bits (438), Expect = 6e-41, Method: Composition-based stats.
Identities = 68/301 (23%), Positives = 109/301 (36%), Gaps = 41/301 (14%)
Query 1610 HNSHEGKTFYVLPNDDTL-RVEAFEYYHTTDP----SFLGRYMSALNHTKKWKYPQVNGL 1664
+ E +T V T V+ E DP + +K +NG
Sbjct 1024 SSQEEVETVEVADITSTEEDVDIVEVSAKDDPWAAAVDVQEAEQFNPSLPPFKTTNLNGK 1083
Query 1665 TSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGE 1724
+K DNNC++ LQ + FN +A+ + + G+ +F L A G
Sbjct 1084 IILKQGDNNCWINACCYQLQAFDF-FN----NEAWEKFKKGDVMDFVNLCYAATTLARGH 1138
Query 1725 LGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQ 1784
GD + + + + K VL C CG+++ L E ++ T E F GV
Sbjct 1139 SGDAEYLLELMLN--DYSTAKIVLAAKCG-CGEKEIVL---ERAVFKLTPLKESFNYGVC 1192
Query 1785 IPC----TCGKQATKY-------LVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQC 1833
C TC + + ++ +++P M P + + YTG Q
Sbjct 1193 GDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHAV----------YTGTTQN 1242
Query 1834 GHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEID 1893
GHY + E YC+DG + K + + + +F N T KP V E
Sbjct 1243 GHY-MVDDIEHGYCVDG-MGIKPLKKRCYTSTLFINANVMTRAEKPKQEF--KVEKVEQQ 1298
Query 1894 P 1894
P
Sbjct 1299 P 1299
Score = 141 bits (356), Expect = 3e-31, Method: Composition-based stats.
Identities = 55/296 (19%), Positives = 101/296 (34%), Gaps = 23/296 (8%)
Query 1554 DNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQF-GPTYLDGADVTKIKPHNS 1612
D + + +I V T DN+N V TYG+Q G + DVT P
Sbjct 1475 DQERQTIENFFSCSIPVNVTEDNVNHERVSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAF 1534
Query 1613 HEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADN 1672
G+ + ++ +Y D + ++ + K++ + K DN
Sbjct 1535 DVGQKV-----IKAIDIDWQAHYGFRDA---AAFSASSHDAYKFEVVTHSNFIVHKQTDN 1586
Query 1673 NCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETM 1732
NC++ L LQ+++ ++ P ++ + + F ++ GE GD +
Sbjct 1587 NCWINAICLALQRLKPQWKFPGVRGLWNEFLERKTQGFVHMLYHISGVKKGEPGDAELML 1646
Query 1733 SYLFQHANLDSCKRV-LNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGK 1791
L + D V C C + G + G C G
Sbjct 1647 HKLGDLMDNDCEIIVTHTTACDKC-AKVEKFVGPVVAAPLAI-------HGTDETCVHGV 1698
Query 1792 QATKYLVQQESPFVMMS--APPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETL 1845
+ Q + + S P L+ + C Y+G+ + GHY + ++ L
Sbjct 1699 SVNVKVTQIKGTVAITSLIGPIIGEVLEATGYIC---YSGSNRNGHYTYYDNRNGL 1751
Score = 68.2 bits (165), Expect = 4e-09, Method: Composition-based stats.
Identities = 49/251 (20%), Positives = 75/251 (30%), Gaps = 43/251 (17%)
Query 174 MRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCRE 233
++ G YVD CG DG P+ + +
Sbjct 102 LKIARTGRGAIYVDQYMCGADGKPV----------------IEGDFKDYFGDEDIIEFEG 145
Query 234 HEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKL 293
E+ AW T R EK QT F I+ + N + P+ + N + + P V+K
Sbjct 146 EEYHCAWTTVRDEKPLNQQTLFTIQEIQY----NLDIPHKL--PNCATRHVAPPVKKNSK 199
Query 294 DGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATC-EFCGTENLTKE 352
+ +Y + S M C + T F+ AT CG+E+
Sbjct 200 IVLSEDYKKLYDIFG---------SPFMGNGDCLSKCFDTLHFIAATLRCPCGSESSGVG 250
Query 353 GATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFS 412
T C S +L + + T + G F CV
Sbjct 251 DWT-----------GFKTACCGLSGKVKGVTLGDIKPGDAVVTSMSAGKGVKFFANCVLQ 299
Query 413 YVGCHNKCAYW 423
Y G + W
Sbjct 300 YAGDVEGVSIW 310
Score = 49.3 bits (116), Expect = 0.002, Method: Composition-based stats.
Identities = 50/302 (17%), Positives = 96/302 (32%), Gaps = 27/302 (9%)
Query 748 PTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMM 807
V+ + +P+ +E V+ G + I G + +D Y
Sbjct 811 DVPVVDNGTISTADWSEPILLEPAEYVKPKNNGNVIVIAGYTFYKDEDEHFYP--YGFGK 868
Query 808 VTNNTFTLKGGAPTKVTFGDD-TVIEVQGYKSVNITFELD-ERIDKVLNEKCSA---YTV 862
+ + GG V+F ++ V E+ V + FE D E + VL +T
Sbjct 869 IVQRMYNKMGGGDKTVSFSEEVDVQEIAPVTRVKLEFEFDNEIVTGVLERAIGTRYKFTG 928
Query 863 ELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYC 922
E E DA+ TL G++L+ + +++D G F + +
Sbjct 929 TTWEEFEESISEELDAIFDTL-------ANQGVELEGY-----FIYDTCGGFDIKNPDGI 976
Query 923 SFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDD 982
D + + E + E+D + + +E + +EE E + D
Sbjct 977 MISQYDINITADEKSEVSASSEEEEVESVEEDPENEIVEASEGAEGTSSQEEVETVEVAD 1036
Query 983 DSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKN 1042
+ + V+VQ + + + F L + +K
Sbjct 1037 ITSTEEDVDIVEVSAKDDPWAAAVDVQEAEQFNPS-------LPPFKT-TNLNGKIILKQ 1088
Query 1043 AD 1044
D
Sbjct 1089 GD 1090
>sp|P18457|R1AB_CVPFS Replicase polyprotein 1ab (Fragment) OS=Porcine
transmissible gastroenteritis coronavirus (strain FS772/70)
OX=11150 GN=rep PE=3 SV=1
Length=533
Score = 757 bits (1954), Expect = 0.0, Method: Composition-based stats.
Identities = 265/533 (50%), Positives = 366/533 (69%), Gaps = 8/533 (2%)
Query 6569 APLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEAVKT 6626
+ + FD + G + F R+ VLI+ +VKGL ++ + LN + + +G T
Sbjct 3 SEVVTCFDNSIAGSFERFTTTRDAVLISNNAVKGLS-AIKLQYGLLNDLPVSTVGNKPVT 61
Query 6627 QFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEH 6686
+ Y +K V+Q+ ++Y+TQ R + FKPRS ME DFL + FI++Y LE Y FEH
Sbjct 62 WYIYVRKNGEYVEQI-DSYYTQGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEH 120
Query 6687 IVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIP-MDSTVKNYFITDAQTGSSKCVCS 6745
+V+GD S + +GG+HLLI + K F +++F+ DST+K+ IT A SSK VC+
Sbjct 121 VVFGDVSKTTIGGMHLLISQVRLAKMGLFSVQEFMNNSDSTLKSCCITYADDPSSKNVCT 180
Query 6746 VIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQP 6805
+D+LLDDFV IIKS DL+VVSKVV V +D +MLWC++ H++TFYP+LQS++ W P
Sbjct 181 YMDILLDDFVTIIKSLDLNVVSKVVDVIVDCKAWKWMLWCENSHIKTFYPQLQSAE-WNP 239
Query 6806 GVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRV 6865
G +MP LYK+QRM LE+C+L NYG LP GI NV KYTQLCQYLNT TL VP+ MRV
Sbjct 240 GYSMPTLYKIQRMCLERCNLYNYGAQVKLPDGITTNVVKYTQLCQYLNTTTLCVPHKMRV 299
Query 6866 IHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLI 6925
+H GA GVAPG+ VLR+WLP +LVD+DL D+VSDAD ++ GDC +++ +K+DL+
Sbjct 300 LHLGAAGASGVAPGSTVLRRWLPDDAILVDNDLRDYVSDADFSVTGDCTSLYIEDKFDLL 359
Query 6926 ISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHF 6985
+SD+YD TK++ EN SK+GFFTYI GFI++KL+LGGSVAIKITE SWN DLY+L+ F
Sbjct 360 VSDLYDGSTKSIDGENTSKDGFFTYINGFIKEKLSLGGSVAIKITEFSWNKDLYELIQRF 419
Query 6986 AWWTAFVTNVNASSSEAFLIGCNYLGK--PREQIDGYVMHANYIFWRNTNPIQLSSYSLF 7043
+WT F T+VN SSSE FLIG NYLG + +DG +MHANYIFWRN+ + LS S+
Sbjct 420 EYWTVFCTSVNTSSSEGFLIGINYLGPYCDKAIVDGNIMHANYIFWRNSTIMALSHNSVL 479
Query 7044 DMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVNN 7096
D KF + +++LKE ++N+M++ LL KG+L+IR N +++ + VN
Sbjct 480 DTPKFKCRCNNALIVNLKEKELNEMVIGLLRKGKLLIRNNGKLLNFGNHFVNT 532
>sp|P12723|R1AB_IBVK Replicase polyprotein 1ab (Fragment) OS=Avian
infectious bronchitis virus (strain KB8523) OX=11126 GN=rep
PE=3 SV=1
Length=521
Score = 647 bits (1668), Expect = 0.0, Method: Composition-based stats.
Identities = 242/523 (46%), Positives = 337/523 (64%), Gaps = 15/523 (3%)
Query 6581 GQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQFNYYKKVDGVVQ 6639
G F A N VL++ K P + NG++L A YK+V+G
Sbjct 2 GGGQSFLAADNAVLVSTQCYKRHSYVEIPSNLLVQNGMSLKDGA---NLYVYKRVNGAFV 58
Query 6640 QLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGG 6699
LP T TQ R+ + F+PRS +E DFL+++ ++F+E+Y + +HI+YG+ QLGG
Sbjct 59 TLPNTLNTQGRSYETFEPRSDVERDFLDMSEEDFVEKYG-KDLGLQHILYGEVDKPQLGG 117
Query 6700 LHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEI-- 6757
LH +IG+ + + + + DS V + A GS K VC+V+DLLLDDF+E+
Sbjct 118 LHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVLADNGSYKQVCTVVDLLLDDFLELLR 177
Query 6758 -IKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQ 6816
I ++ + SKVV V+IDY I+FM W +DG ++T YP+LQS+ W G MP LYK+Q
Sbjct 178 NILNEYGTNKSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQSA--WTCGYNMPELYKVQ 235
Query 6817 RMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGV 6876
++E C++ NYG TLP GIMMNVAKYTQLCQYL+ T+ VP+NMRV+HFGAGSDKGV
Sbjct 236 NCVMEPCNIPNYGVGITLPSGIMMNVAKYTQLCQYLSKTTVCVPHNMRVMHFGAGSDKGV 295
Query 6877 APGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY---DPK 6933
APG+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC T +K+DL+ISDMY D K
Sbjct 296 APGSTVLKQWLPEGTLLVDTDIVDYVSDAHVSVLSDCNKYKTEHKFDLVISDMYTDNDSK 355
Query 6934 TKNVT-KENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFV 6992
K+ N+ + F Y+ F++ LALGGS A+K+TE SW+ LY + AWWT F
Sbjct 356 RKHGGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKLTETSWHESLYDIAQDCAWWTMFC 415
Query 6993 TNVNASSSEAFLIGCNYLGKP-REQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLK 7051
T VNASSSEAFLIG NYLG + ++ G +HANYIFWRN N +Q S+YS+FD++KF L+
Sbjct 416 TAVNASSSEAFLIGVNYLGASVKVKVSGKTLHANYIFWRNCNYLQTSAYSIFDVAKFDLR 475
Query 7052 LRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLV 7094
L+ T V++LK Q D++ +L+ G+L++R+ +SD V
Sbjct 476 LKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 518
>sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11156
GN=rep PE=1 SV=1
Length=6857
Score = 612 bits (1579), Expect = 2e-173, Method: Composition-based stats.
Identities = 140/602 (23%), Positives = 254/602 (42%), Gaps = 59/602 (10%)
Query 4810 DFYDFAVSKGFFKEGSSV--ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEV 4867
FYD + + G K+F++ + A++D YY Y + L V +
Sbjct 4908 PFYDVGLCQELTDAGVDCGEAFKYFYYLSNPAGALADVCYYDYQGTGFYSPKLLAGVYDF 4967
Query 4868 VDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWG-KARLYYDSMSYEDQDALFAYTKRN 4926
+ + +CY IN + + N G + Y ++ E+ LF Y ++
Sbjct 4968 MKRVTECYR---INERFTYEQAKPRKSSMGINITGYQQDAVYRALGPENIARLFEYAQKA 5024
Query 4927 VIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKL---LKSIAATRGATVVIGT 4983
+P T++ K+A+SAK RARTV+ S ++ R H+ + + +A G +IG
Sbjct 5025 PLPFCTKIITKFALSAKARARTVSSCSFIASTIFRFAHKPVTSKMVEVAQNSGGFCLIGV 5084
Query 4984 SKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHR 5043
SK+ + LK Y +E + G DY KCDR P R + + +L +
Sbjct 5085 SKYGLKFSKFLKDKYGAIEGFDVFGSDYTKCDRTFPLSFRALTAALLYE----LGEWDEK 5140
Query 5044 FYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLS-- 5101
+ NE + + ++C G L KPGGTSSGDATTA++N+ +N +LS
Sbjct 5141 SWLYLNEVNSYMLDTMLCDGMLLNKPGGTSSGDATTAHSNTFYNYMVHYVVAFKTILSDL 5200
Query 5102 TDGNKIADKYVRNL----QHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVC 5157
++GNK+ N ++++ L ++ F+N LSDD+ +
Sbjct 5201 SEGNKVMRIAAHNAYTTGDYQVFNTLLEDQFQTNYFLN-------------FLSDDSFI- 5246
Query 5158 FNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDD 5217
F+ A + + + +NF + L + + + K W+ + EFCS H ++K +
Sbjct 5247 FSKPEALK--IFTCENFSNKLQTILHTKVDQTKSWSTKGHIE---EFCSAH--IIKTDGE 5299
Query 5218 YVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYL 5277
Y +L P R+L + +D + D M RFV++ ++ +++ + + +F ++L
Sbjct 5300 YHFL--PSRGRLLASLLILDKLSDVDIYYM--RFVAILCESAVYSRYQPEFFNGLFQVFL 5355
Query 5278 QYIRKLH-----DELTGHML--DMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVG--- 5327
+++ D +L + Y ++ N+ + E Q
Sbjct 5356 DKVQQFRKDYCCDPCPPQLLEREFYENLVFTSNSEVGIVDCYLENFKLQCEFKQQANFDK 5415
Query 5328 ACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQL 5387
C C + C C LC C Y HV+ ++H V + + C C ++ +L
Sbjct 5416 VCFCCPNPAVSVCEECYVPLPLCAYCYYVHVVISNHSKVE--DKFKCF---CGQDNIREL 5470
Query 5388 YL 5389
Y+
Sbjct 5471 YI 5472
Score = 320 bits (819), Expect = 4e-85, Method: Composition-based stats.
Identities = 105/401 (26%), Positives = 181/401 (45%), Gaps = 60/401 (15%)
Query 6616 GVTLIGEAVKTQFNYYKK--VDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEF 6673
V + EA Q YY + + +LP+T F+ R L + + +LA++
Sbjct 6424 SVHIYIEATGEQPLYYLQQGKGESLFELPDTLFSTGR-LYNLDHDAAQNFNVKQLAIETM 6482
Query 6674 IERYKLEGYAFEHIVYGDFSH--SQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYF 6731
+ H+ GDF+ + +GG+H ++ L +K S + VK
Sbjct 6483 PNNH--------HVFSGDFTEVGTDIGGVHHVVAL-NGYKGSIIP--------NYVKPIA 6525
Query 6732 ITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV-VSKVVKVTIDYTEISFMLWCK-DGH 6789
G + +++D+ + E +K Q V VSKV+ V ID+ ++ FM++ +
Sbjct 6526 TGLINVGRAVKRTTLVDVCANQLYEKVKQQLEGVKVSKVIFVNIDFQDVQFMVFANGEDD 6585
Query 6790 VETFYPK---LQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSAT-LPKGIMMNVAKY 6845
++TFYP+ ++S W PN+ + DL+NYG + T +P+ + N AKY
Sbjct 6586 IQTFYPQKDFVRSYYEW------PNILP---QIESHYDLKNYGQNPTFMPQPV--NFAKY 6634
Query 6846 TQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDA 6905
TQ+C ++ + V N V H GA G +PG VL + L+ D+ D+
Sbjct 6635 TQICTFIQD-HVKVARNALVWHLGAAGVDGCSPGDIVLSSFFKE-CLVYSWDIKDY---- 6688
Query 6906 DSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSV 6965
+ + D + + +LI+SD+Y+ + NV++ D +LALGG++
Sbjct 6689 --STLLDKHSYDCNFRPNLIVSDIYN-VSSNVSEVLDD-----------CVHRLALGGTI 6734
Query 6966 AIKITEHSW-NADLYKLMGHFAWWTAFVTNVNASSSEAFLI 7005
K TE S + L + +F+ F VN SSSE F++
Sbjct 6735 VFKTTESSRPDIQLSQFTKYFSAVQFFTAGVNTSSSEVFVV 6775
Score = 190 bits (482), Expect = 6e-46, Method: Composition-based stats.
Identities = 68/307 (22%), Positives = 117/307 (38%), Gaps = 26/307 (8%)
Query 5598 MQKYSTLQGPPGTGKSHFAIG--LALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS 5655
+ + + GPPGTGK+ F L+ S R VY A +H V + EK +D
Sbjct 5659 YENVTFVMGPPGTGKTTFVYDTYLSKASSSNRFVYCAPTHRLVGDMDEK------VDGAV 5712
Query 5656 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5715
+ R + + + + CT N LP + +++ DE+S+ + + + +
Sbjct 5713 VVSAYNDRTYRNPVWNKDDSYG-VLLCTHNTLPFIKSAVLIADEVSLIPPHVMIKI-LSM 5770
Query 5716 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5775
K V +GDP QL +P K + + F L++ +L C RCP +I+
Sbjct 5771 GFKKVVLLGDPFQL-SPVYKNHKVHFKYDTF----YLLQLATQKRYLTACYRCPPQILSA 5825
Query 5776 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAI-NRPQIGVVREFLTRNPAWRKAV 5834
S D + + G VS + N V+ P + V
Sbjct 5826 FSKPYCDVGVDLVSFNNK-------PGKFDIIVSKQLANIQDFSVLSVLSKEYPGY---V 5875
Query 5835 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKV 5894
+ Y + A + T+DSSQG+ + + S VNR V +R+
Sbjct 5876 ILVNYRAAVDYAMQNGLGDVTTIDSSQGTTAANHLLVLFGASNFSKTVNRVIVGCSRSTT 5935
Query 5895 GILCIMS 5901
++ +
Sbjct 5936 HLVVVCC 5942
Score = 137 bits (345), Expect = 5e-30, Method: Composition-based stats.
Identities = 54/248 (22%), Positives = 97/248 (39%), Gaps = 25/248 (10%)
Query 966 SAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEV 1025
++ + E+ + ++ D ++ T + + + L++
Sbjct 1629 CLTVKVNAKNEKLDIGSQCERVFVDYDVKKNEWTLSPEEGEDSDDNLDLPF--------- 1679
Query 1026 NSFSGYLKLTDNVYIKNADIVEEAKKVK----PTVVVNAANVYLKHGGGVAGALNKATNN 1081
+ + NV + D + +K VVN AN LKHGGG+A ++
Sbjct 1680 EQYYEFKIGQTNVVLVQDDFKSVFEFLKSEQGVDYVVNPANSQLKHGGGIAKVISCMCGP 1739
Query 1082 AMQVESDDYIATNGPLKVGGSCVLSGHNLAKHC--LHVVGPNVNKGEDIQLLKSAYENF- 1138
+Q S++YI N + V + G L K +H VGP V+ G+ Q L A+ +
Sbjct 1740 KLQAWSNNYITKNKTVPVTKAIKSPGFQLGKKVNIIHAVGPRVSDGDVFQKLDQAWRSVF 1799
Query 1139 ---NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKS 1195
+L +LS GIFG S + V A DK+L +V++ +E +
Sbjct 1800 DLCEDQHTILTSMLSTGIFGCTVNDSFNTFLSNV------ARLDKSLVVFVVTNMVEQYN 1853
Query 1196 EKQVEQKI 1203
+ K+
Sbjct 1854 QAFAVIKM 1861
Score = 102 bits (255), Expect = 1e-19, Method: Composition-based stats.
Identities = 33/101 (33%), Positives = 50/101 (50%), Gaps = 7/101 (7%)
Query 6108 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYAC--WHHSIGFDYVYNPF 6165
F+L++ +L S+K++V+ C C A C Y C + + + N
Sbjct 6077 FILYSCSNDLKSLKFYVEFDTCYFCS-CGEMAICL-MRDGNYKCRNCYGGMLISKLVNCK 6134
Query 6166 MIDVQQWGFTGNLQSNHDLYCQ-VHGNAHVASCDAIMTRCL 6205
+DVQ+ LQ HD CQ HG++H A CDA+MT+CL
Sbjct 6135 YLDVQKERV--KLQDAHDAICQQFHGDSHEALCDAVMTKCL 6173
Score = 55.5 bits (132), Expect = 3e-05, Method: Composition-based stats.
Identities = 46/209 (22%), Positives = 78/209 (37%), Gaps = 31/209 (15%)
Query 4407 SAARLTPCGTGT-STDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVK 4465
SA R G + D+ + AG K K+N + + + F++K
Sbjct 4575 SACRHLCFQNGAYQSSRSKHYIDLATEYNAGIVKVNKSNTHSVEYQSKR-------FMIK 4627
Query 4466 RHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRH 4525
R E P++ H + + R +++++ DLVYA+
Sbjct 4628 R----VKDQSEFALAKTAFLPSIIPHHM----EKQNGEWFLIRGPTSQWSLGDLVYAIWL 4679
Query 4526 FDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFC 4585
D+ D L E +N D++ + + F+ N + A+L
Sbjct 4680 GDQ---DYLSECGFVFNPSRDEFLDDANQRSFLAN------------LLEPAILNFSHIY 4724
Query 4586 DAMRNAGIVGVLTLDNQDLNGNWYDFGDF 4614
++ + LTLDN DLNG YDFGD+
Sbjct 4725 WQVKMCKVPYKLTLDNVDLNGQLYDFGDY 4753
Score = 41.6 bits (96), Expect = 0.39, Method: Composition-based stats.
Identities = 39/246 (16%), Positives = 82/246 (33%), Gaps = 41/246 (17%)
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
+ +P + + + +++ ++ + + +Y+ + F + + +
Sbjct 3055 FEIISPYV--FVFIVVIFTVIFLILIRLYIVMYSYFKVFTYVVFKLLFVNIIMVLFVVCL 3112
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIIC 3147
V + V + + LYL F + + + ++ M V +W+ + +
Sbjct 3113 PPLVPGVVFVLALWLCDSVMFLLYLAFLSLFILPWFYVLFFLFMVGGFVFWWMMRSADVV 3172
Query 3148 ISTKHFYWFFSNYLKRRVVFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ +G++F TFE+ + C F LN + + +LL +
Sbjct 3173 ----------------HLTTDGLTFNGTFEQISKCVFPLNP----LIVNRMLLDCQMSHS 3212
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGF 3266
L +K K G LA + +G YQP S QS F
Sbjct 3213 DLVEKSKLKTTEGK-------------LANEMMKVFMTGETSYYQPSNFSF-----QSVF 3254
Query 3267 RKMAFP 3272
K P
Sbjct 3255 SKATSP 3260
>sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus
1 OX=360393 GN=rep PE=2 SV=1
Length=6733
Score = 605 bits (1561), Expect = 2e-171, Method: Composition-based stats.
Identities = 141/602 (23%), Positives = 246/602 (41%), Gaps = 59/602 (10%)
Query 4810 DFYDFAVSKGFFKEGSSV--ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEV 4867
YD + + G K+F++ + A++D +Y Y + L V +
Sbjct 4784 PLYDVGLCQELTDAGVDCGEAFKYFYYLSNPAGALADVCFYDYQGTGFYSPKLLAGVYDF 4843
Query 4868 VDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWG-KARLYYDSMSYEDQDALFAYTKRN 4926
+ + CY + + + N G + Y ++ E+ LF Y ++
Sbjct 4844 MKRVTTCYK---TDERFTYEQAKPRKSSMGINITGYQQDAVYRALGPENITKLFEYAQKA 4900
Query 4927 VIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKL---LKSIAATRGATVVIGT 4983
+P T++ K+A+SAK RARTV+ S ++ R H+ + + +A +IG
Sbjct 4901 PLPFCTKIITKFALSAKARARTVSSCSFIASTIFRFAHKPVTSKMVEVAQNSQGFCLIGV 4960
Query 4984 SKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHR 5043
SK+ + LK Y +E + G DY KCDR P R + + +L
Sbjct 4961 SKYGLKFSKFLKDKYGAIEQFDVFGSDYTKCDRTFPLSFRALTAALLYE----LGGWEED 5016
Query 5044 FYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLS-- 5101
+ NE + + ++C G L KPGGTSSGDATTA++N+ +N +LS
Sbjct 5017 SWLYLNEVNSYMLDTMLCDGMLLNKPGGTSSGDATTAHSNTFYNYMVHYVVAFKTILSDL 5076
Query 5102 TDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFS----MMILSDDAVVC 5157
+D NK+ +R H Y F L + F + LSDD+ +
Sbjct 5077 SDCNKV----MRIAAHNAYTT---------GDYGVFNTLLEEQFQTNYFLNFLSDDSFI- 5122
Query 5158 FNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDD 5217
F+ A + + + +NF + L + + K W T + EFCS H ++K +
Sbjct 5123 FSKPGALK--IFTCENFSNKLQTILHTKVDLTKSWATTGHIE---EFCSAH--IIKTDGE 5175
Query 5218 YVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYL 5277
Y +L P R+L + +D + D M RFV++ ++ +++ + + +F ++L
Sbjct 5176 YHFL--PSRGRLLASLLILDKLSDVDIYYM--RFVAILCESAVYSRYQPEFFNGLFQVFL 5231
Query 5278 QYIRKLH-----DELTGHMLD--MYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVG--- 5327
+++ D +LD Y ++ NT + E Q G
Sbjct 5232 DKVQQFRKDYCCDPCPTQLLDRQFYENLVFTSNTEVGLVDCYLENFKLQCEFKQQAGFDR 5291
Query 5328 ACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQL 5387
C C + C C LC C Y HV+ +SH + + + C C D+ +L
Sbjct 5292 VCFCCPNPAVSVCEECYVPLPLCAYCYYVHVVISSHCKIE--DKFKCP---CGQDDIREL 5346
Query 5388 YL 5389
++
Sbjct 5347 FI 5348
Score = 313 bits (801), Expect = 5e-83, Method: Composition-based stats.
Identities = 107/401 (27%), Positives = 182/401 (45%), Gaps = 60/401 (15%)
Query 6616 GVTLIGEAVKTQFNYYKKVDG--VVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEF 6673
V + EA Q YY ++ +++LPET F+ R L + + +LA++
Sbjct 6300 SVHIYVEATGEQPLYYLQLGNGESLRELPETLFSTGR-LYNLEHDPSKNFNVQQLAIETI 6358
Query 6674 IERYKLEGYAFEHIVYGDFSH--SQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYF 6731
+ + H+ GDF+ + +GG+H ++ L +K S + VK
Sbjct 6359 PKNH--------HVFAGDFTDVGTDIGGVHHVVAL-NGYKGSIIP--------NYVKPIA 6401
Query 6732 ITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV-VSKVVKVTIDYTEISFMLWCK-DGH 6789
G S +++D+ + E +K Q V VSKV+ V ID+ E+ FM++ K +
Sbjct 6402 TGLINVGRSVKRTTLVDVCANQLYEKVKQQIAGVKVSKVIFVNIDFQEVQFMVFAKGEDD 6461
Query 6790 VETFYPK---LQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGD-SATLPKGIMMNVAKY 6845
++TFYP+ ++S W +P L DL+NYG +P+ + N AKY
Sbjct 6462 IQTFYPQKEFIRSYYEWPT--ILPEL-------ESHYDLKNYGQDPQFMPQPV--NFAKY 6510
Query 6846 TQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDA 6905
TQ+C ++ + V N + H GA G +PG VL + L+ D+ D+ +
Sbjct 6511 TQICTFIQE-HVKVARNSLIWHVGAAGIDGCSPGDIVLSSFFKE-CLVYSWDVKDYDT-- 6566
Query 6906 DSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSV 6965
+ + + +LI+SD+Y+ + NV++ + +LALGG++
Sbjct 6567 ----LLEKHNYDCNFRPNLIVSDVYN-VSSNVSEVLED-----------CVHRLALGGTI 6610
Query 6966 AIKITEHSW-NADLYKLMGHFAWWTAFVTNVNASSSEAFLI 7005
K TE S + L K+ +FA F VN SSSE F++
Sbjct 6611 IFKTTESSRPDIQLSKVTKYFAAVHFFTAGVNTSSSEVFVV 6651
Score = 199 bits (505), Expect = 1e-48, Method: Composition-based stats.
Identities = 69/307 (22%), Positives = 120/307 (39%), Gaps = 26/307 (8%)
Query 5598 MQKYSTLQGPPGTGKSHFAIG--LALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS 5655
+ + + GPPGTGK+ F L+ PS R VY A +H V + EK +D
Sbjct 5535 YENVTFVMGPPGTGKTTFVYNTYLSKASPSNRFVYCAPTHRLVGDMDEK------VDGAV 5588
Query 5656 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5715
+ R +K + + + + CT N LP + +++ DE+S+ + + + +
Sbjct 5589 VVSAYNDRTYRNPVWKKDDSYD-VLLCTHNTLPFIKSAVLIVDEVSLIPPHVMIKI-LSM 5646
Query 5716 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5775
K V +GDP QL +P K + + F L++ +L C RCP +I+
Sbjct 5647 GFKKVVLLGDPFQL-SPVYKNHKVHFKYDTF----YLLQLATQKRYLTACYRCPPQILSA 5701
Query 5776 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAI-NRPQIGVVREFLTRNPAWRKAV 5834
S D + + G VS + N V+ P + V
Sbjct 5702 FSKPYCDVGVDLVSFNNK-------PGKFDIIVSKQLANMQDFSVLSVLSKEYPGY---V 5751
Query 5835 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKV 5894
+ Y + A + T+DSSQG+ + + S +NR V +R+
Sbjct 5752 ILVNYRAAVDYAMQNGLGDVTTIDSSQGTTAANHLLVLFGASNFSKTINRVIVGCSRSTT 5811
Query 5895 GILCIMS 5901
++ +
Sbjct 5812 HLVVVCC 5818
Score = 126 bits (317), Expect = 9e-27, Method: Composition-based stats.
Identities = 52/252 (21%), Positives = 89/252 (35%), Gaps = 18/252 (7%)
Query 929 EDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSA-ALQPEEEQEEDWLDDDSQQT 987
+E + + +E T + L + L + + E + LD S
Sbjct 1543 CEEFDSAYTLQTISDEVSFETSTSPELVACVLAYAIGYELCLTVKTDGECESLDVGSSLE 1602
Query 988 VGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVE 1047
D + T ++ ++EL N + + +V + D
Sbjct 1603 QVYVDYDVSKNVWDLSTHLQDDSSDDLELP-------FNQYYEFKVGRASVVLVQDDFKS 1655
Query 1048 EAKKVK----PTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSC 1103
+K VVN AN LKHGGG+A ++ + S++YI L V +
Sbjct 1656 VYDFLKSEQGVDYVVNPANNQLKHGGGIAKVISCMCGPKLTSWSNNYIKQYKKLGVTCAI 1715
Query 1104 VLSGHNLAK--HCLHVVGPNVNKGEDIQLLKS----AYENFNQHEVLLAPLLSAGIFGAD 1157
G L K +HVVGP + + L++ ++N +L +LS GIFG
Sbjct 1716 RSPGFQLGKGVQIIHVVGPKSADSDVVNKLEASWRSVFQNVKPDTTVLTSMLSTGIFGCS 1775
Query 1158 PIHSLRVCVDTV 1169
S + +
Sbjct 1776 VTDSATTLLSNL 1787
Score = 113 bits (283), Expect = 7e-23, Method: Composition-based stats.
Identities = 37/134 (28%), Positives = 60/134 (45%), Gaps = 21/134 (16%)
Query 6108 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYAC--WHHSIGFDYVYNPF 6165
F+L++ +L S+K++V+ G C C A C Y C + ++ + N
Sbjct 5953 FILYSCSNDLKSLKFYVEFGTNYFCS-CGELAICL-MRDGLYKCRNCYGNMSISKLVNCK 6010
Query 6166 MIDVQQWGFTGNLQSNHDLYCQ-VHGNAHVASCDAIMTRC--LAVHEC------------ 6210
+DVQ+ LQ HD CQ HG++H A CDA+MT+C LA ++
Sbjct 6011 YLDVQKERI--KLQDAHDAICQQFHGDSHEALCDAVMTKCLYLASYDAAFKDTIHVKYKD 6068
Query 6211 FVKRVDWTIEYPII 6224
+ + I P +
Sbjct 6069 LCLEIQYKITSPYV 6082
Score = 53.9 bits (128), Expect = 8e-05, Method: Composition-based stats.
Identities = 52/227 (23%), Positives = 94/227 (41%), Gaps = 31/227 (14%)
Query 3047 IVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYS 3106
+V I IV L ++ F +++VV LLF+ + VL + + +PGV
Sbjct 2944 VVLVAIFTIVFLFLLRMYIVMYSYFKVFTYVVFK--LLFVNTVMVLFVVCLPPLVPGVV- 3000
Query 3107 VIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVV 3166
L +L + V FL ++ + +F ++P++ + +++ + F+W + +
Sbjct 3001 ---FVLALWLCDSVVFLLYLAVLSLF--ILPWFYVMLFVLIVGGFVFWWMMKSSDVVHLT 3055
Query 3167 FNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTS 3225
+G++F TFE+ + C F LN + + +LL + L +K K G
Sbjct 3056 PDGLTFNGTFEQVSKCVFPLNP----LIVNRLLLDCRMSHSDLVEKSKLKTTEGK----- 3106
Query 3226 YREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFP 3272
LA + +G YQP S QS F K+ P
Sbjct 3107 --------LATEMMKVFMTGETAYYQPSNFSF-----QSVFSKVVSP 3140
Score = 51.2 bits (121), Expect = 6e-04, Method: Composition-based stats.
Identities = 40/188 (21%), Positives = 73/188 (39%), Gaps = 30/188 (16%)
Query 4427 FDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCP 4486
D+ + AG K K+N + K + F++KR E P
Sbjct 4472 IDLATEYNAGIVKVNKSNTHSVEYKGQR-------FMIKR----VKDQHEFALARTAFLP 4520
Query 4487 AVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDD 4546
++ H + + + R T++++ DLVYA+ D+ L E +N D
Sbjct 4521 SIIPHHM----VHQNGEWFLVRGPTTQWSLGDLVYAIWLGDQ---AYLDECGFVFNPSRD 4573
Query 4547 DYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNG 4606
++ + + ++ N + A+L + ++ + +TLDN DL G
Sbjct 4574 EFLDDANQRSYLAN------------LLEPAILSFCEIFHCVKGCQVPYKITLDNLDLKG 4621
Query 4607 NWYDFGDF 4614
YDFGD+
Sbjct 4622 QLYDFGDY 4629
>sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream
virus (isolate Blicca bjoerkna L./Germany/DF24/00) OX=766180
GN=rep PE=1 SV=1
Length=6872
Score = 588 bits (1516), Expect = 4e-166, Method: Composition-based stats.
Identities = 145/652 (22%), Positives = 263/652 (40%), Gaps = 102/652 (16%)
Query 4807 FNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNA--AISDYDYYRYNLPTMCDIRQLLFV 4864
+ + FYD + + G ++ + Q G A+ D+ YY YN P D L V
Sbjct 4888 YKRPFYDLDLIQRMNSAGLNLSETTGYHYQCGTTTEAVEDFMYYNYNSPKSFDPSYLKSV 4947
Query 4865 VEVV-DKYFDCYDGGCINANQVIVNNLDKSAGFP-FNKWGK------ARLYYDSMSYEDQ 4916
+ DK+ I+ ++ L+ +G P + G + ++++ +
Sbjct 4948 YTYMRDKFMKI-----ISTDE----KLNHQSGAPRMSSMGVGVSGFFQKTVWNALPEDFS 4998
Query 4917 DALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRG 4976
L + V+P T + K+ K R RT+ G S ++ R H+ + + T
Sbjct 4999 PRLLDTASKTVMPFSTNIVKKFQRQKKTRVRTLGGSSFITSSIFRMLHKPVTNKMVQTAQ 5058
Query 4977 ATV---VIGTSKFYGGWHNMLKTVYSD-VENPHLMGWDYPKCDRAMPNMLRIMASLVLAR 5032
A + +IG SKF G+H L + + +E+ +MG DY KCDR+ P + R +++ +
Sbjct 5059 ANIGPFLIGISKFNLGFHKYLSAHHPNGIEDCQVMGADYTKCDRSFPVVCRALSAALFYE 5118
Query 5033 KHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAV 5092
L + NE L + G ++ KPGGT+SGD+TTA++NS +N +
Sbjct 5119 ----LGHLEPNNHWFLNEMFAFLLDPSFISGHIFNKPGGTTSGDSTTAFSNSFYNYFVHL 5174
Query 5093 TANVNALLSTDGNKIADKYVRNLQHRLYEC-------LYRNRDVDTDFVNEFYAYLRKHF 5145
L+T+ + + + NL H+ + LY + D + F
Sbjct 5175 YIQYLTFLTTEMPP-SYQPLCNLAHQAFSTGNTETYDLYFSMADDLNSTEYF-------- 5225
Query 5146 SMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFC 5205
+ LSDD+ + T + + NF L ++ AK W+ HEFC
Sbjct 5226 -LHFLSDDSFIISKPTAFP---IFTPANFSMKLQNVLGCYVDPAKSWSADGEI---HEFC 5278
Query 5206 SQHTMLVKQGDDYVYLPYPDPSRILGAGC----------FVDDIVKTDGTLMIERFVSLA 5255
S H + + YV PDP+ +L + +V T L + FV+
Sbjct 5279 SSHICKINEKYQYV----PDPNNMLAGLICAPEPTPQDKLIWKLVATCAELAVFHFVNPT 5334
Query 5256 IDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHM-----------LDMYSVMLTNDNT 5304
+ + ++FHL ++ LH E +D Y+ ++ +++
Sbjct 5335 L------------FNNIFHL----LQSLHAEFVSEHSVNLLPPKLLEIDFYTDLIDSEDV 5378
Query 5305 SRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHK 5364
+Y + + + ++Q+ C C++ T C C + +C C Y+H++ T H
Sbjct 5379 EQY--SFLADTLTEKNIIMQSASQCYFCDNATVSTCSDCTVQYPMCAHCAYEHLMLTDHT 5436
Query 5365 LVLSVNPYVCNAPGCDVTDVTQL----YLGGMSYYCKSHKPPISFPLCANGQ 5412
+ +V CD TD L +G + C +H ++ PL + +
Sbjct 5437 PTQVLPCHV-----CDQTDPRHLNHTFVMGTVKVACDNHVEGMALPLVDHAR 5483
Score = 283 bits (725), Expect = 4e-74, Method: Composition-based stats.
Identities = 134/638 (21%), Positives = 225/638 (35%), Gaps = 122/638 (19%)
Query 6391 VPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTR 6450
+P +C+ + G C AN + + Y + G +L Y T
Sbjct 6268 IPAGYPSCV---KIKGKGCTFCANTIAVITELYEDLAKLGLTLSRPIIQQAYTQVET-QI 6323
Query 6451 LQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELW 6510
LQ++ NV++N Q GE+ + + ++TV F N ++ +
Sbjct 6324 LQNITNVSYN---------QFGEMLIQLKDDTVIP---------FIND--FQTSI--HNY 6361
Query 6511 AKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAP 6570
+ R+ +P+P I NLG+ + + + I
Sbjct 6362 SLRSNQPLPNPAIFKNLGIKATLGF--------STPWVPVTTTTTEPHIMSTKILKDNND 6413
Query 6571 LTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNY 6630
++ F + G I P Y
Sbjct 6414 YYHLSPVQLKASPHAFSSITAGYYIYTT-----PMINIPN---------------ETPAY 6453
Query 6631 YKK--VDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFL-ELAMDEFIERYKLEGYAFEHI 6687
Y V G L Y + +R F+ DE+ + H+
Sbjct 6454 YLTHFVHGQSTPLDLGYTSTNRLTT---------KQFIYTPNEDEYKSKLG------HHV 6498
Query 6688 VYGDFSHS--QLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCS 6745
GD S+ +GG+H+L + ++L P + ++ I A +K +
Sbjct 6499 SVGDTSNVSWTIGGMHVLTAFQNI---TNYQLVSG-PANPIMR---INVALERGNKVETT 6551
Query 6746 VIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCK-DGHVETFYPKLQS----- 6799
+D L D+ +I + ++V SK T+D + M + DG ++T YP Q+
Sbjct 6552 ALDTTLQDYYKIATTNKVTV-SKTTFFTLDGGQYRMMNFANPDGTIQTSYPVAQAQSQLI 6610
Query 6800 --SQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIM--MNVAKYTQLCQYLNTL 6855
+ + + P + E D + PK +N+ KY Q+C L +
Sbjct 6611 TNYRIYPSYITWPTFFTN-----EATDCWAIPNYNAPPKNQTCNINIQKYDQMCD-LFAI 6664
Query 6856 TLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCAT 6915
L +P + H G +K +PG VLRQ+ L DL + VSD
Sbjct 6665 DLKIPVKGHIHHLGNAGNK-YSPGDVVLRQYFDQAHL-TSYDLREVVSD--------IPV 6714
Query 6916 VHTANKWD--LIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHS 6973
+H ++W I+SD+Y P T F + ++Q L LGGS+ K+TE S
Sbjct 6715 LHPNDEWKAHFILSDVYAPDT-----------DFTSLALEYMQNHLRLGGSIMWKMTETS 6763
Query 6974 WNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLG 7011
+ +++ +F W A VN SSSE FL Y G
Sbjct 6764 I-LQVNEIVKYFGSWKAVTFAVNYSSSETFLFCAGYTG 6800
Score = 279 bits (714), Expect = 7e-73, Method: Composition-based stats.
Identities = 69/330 (21%), Positives = 137/330 (42%), Gaps = 29/330 (9%)
Query 5570 YVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIG--LALYYPSAR 5627
Y + + + T++ + ++ N ++K + + GPPGTGK+ + + + P+ +
Sbjct 5617 YRKYSKIRRTIHKPRLANRHILN----TLKKATFIIGPPGTGKTTYVMKNFIDTASPANK 5672
Query 5628 IVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNAL 5687
+ Y A +H V ++ + ++ + ++ + +NS + + T A+
Sbjct 5673 VAYIAPTHKLVQSMDQAIWDKYNHTVSVSVVKSELNNNKYN-YPLNSATKTIMLGTPGAV 5731
Query 5688 PETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFN 5747
++FDE++++ + + ++ +++GDP QL P T + +L Y N
Sbjct 5732 CTHAGCTLIFDEVTLSQLNTIINAISVVKPSQVIFLGDPLQL-GPVTHMR--SLSYSYTN 5788
Query 5748 SVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHD 5807
L + L C RCP+ I ++ +K + D + + G
Sbjct 5789 --FPLFQFCNDSRVLSICYRCPSNI--------FNLWVKPYTDSNVRIDPHAAGGDAKII 5838
Query 5808 VSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQ-TVDSSQGSEYD 5866
VS + P + L RN + V + Y I+GL T+DSSQG Y
Sbjct 5839 VSDQCSNPDAYQYVQKLARNNPDK--VLLCNYKK------PIIGLENAVTIDSSQGKTYK 5890
Query 5867 YVIFTQTTETAHSCNVNRFNVAITRAKVGI 5896
+ I T + +NR VA++R+ I
Sbjct 5891 HTIVVLLGNTNFTQVINRAIVAMSRSTHSI 5920
Score = 270 bits (689), Expect = 5e-70, Method: Composition-based stats.
Identities = 81/321 (25%), Positives = 121/321 (38%), Gaps = 60/321 (19%)
Query 4306 QAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL 4365
AI+ P + ++ G S C C DH C G +VQIP ++ F L
Sbjct 4467 IAISQVPVQTIGYLTYAGISVCRQCATKQDHT-----CQYAGYFVQIPREHVSN--IFNL 4519
Query 4366 KNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLT----PCGTG---T 4418
+T C K +C L++ QS Q LN V L P TG
Sbjct 4520 TDT--PPCLHNKFTCTTCQPLQQ---QSKTQQPPLNLVGQCLGLTLDTAFCPFQTGEYKP 4574
Query 4419 STDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKD-----EDDNLIDSYFVVKRHTFSNYQ 4473
S+ Y +I N+ VA K K N ++ +D +V K+
Sbjct 4575 SSREFY--INILNNNVASLRKVFKKNTASIPSENGTIMLKDTGTAHEIYVAKQ------- 4625
Query 4474 HEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDT 4533
LL V +H R + D ++ R T Y++ DLVYA D
Sbjct 4626 -------LLAKGLPVLQHA----RFNHDGTDYLIRYYTTPYSLGDLVYAYMVGD------ 4668
Query 4534 LKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGI 4593
K +L+ + D+ + ++ Y N E++R L + + + A +
Sbjct 4669 FKHMLLALDITDETCLDPGNYSS----------YYNFKEQLRNKLASVIPNVNKILAAEL 4718
Query 4594 VGVLTLDNQDLNGNWYDFGDF 4614
+TLDN DLNG YDFGD+
Sbjct 4719 PLAITLDNIDLNGFLYDFGDY 4739
Score = 117 bits (293), Expect = 5e-24, Method: Composition-based stats.
Identities = 36/110 (33%), Positives = 53/110 (48%), Gaps = 8/110 (7%)
Query 6104 DRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYA--CWHHS---IGF 6158
+RVV+VL+ G +L ++ +G + TC C + AT ++ + C HH+
Sbjct 6074 NRVVYVLYGAGNDLRALTNLNIVG-DYTCEKCTKEATFYTIHREIVHTFCNHHAPSQFPL 6132
Query 6159 DYVYNPFMIDVQQWGFTG-NLQSNHDLYCQV-HGNAHVASCDAIMTRCLA 6206
N ID+Q +L + H C HG+AH AS D IMT CLA
Sbjct 6133 MGTINAQAIDIQHASANKQSLTNTHAEVCNQQHGDAHTASADTIMTGCLA 6182
Score = 59.7 bits (143), Expect = 2e-06, Method: Composition-based stats.
Identities = 127/798 (16%), Positives = 260/798 (33%), Gaps = 145/798 (18%)
Query 3037 PIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTP 3096
P GA A+++ +V I + Y ++ F Y++ V + ++ L++ ++
Sbjct 3240 PTGASSNVAALLMASVVVISMVLFYLYLLQ---IFKFYTNSVIMSFVIQLLTLLATTVST 3296
Query 3097 VYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWF 3156
+ ++ + Y Y +++ ++ T L+ + I +++ Y
Sbjct 3297 PLAVTVQLFVITYGY--------TNWILLTLSLLNLTVLLSTPVGITFVVIYGLYKAYTL 3348
Query 3157 FSNYLKRRVVFNG---VSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNK 3213
F++ + V G +FE+ A TF L ++L SD+ + Q N Y + ++
Sbjct 3349 FTSSGQGCVYNEGGTIRFSGSFEQVANSTFPLTNASCVQLLSDLGITYQQLNVYASSRDR 3408
Query 3214 YKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPS 3273
+ R A L + L+ S +LY+ S + Q+ R +
Sbjct 3409 -----------NVRRLAQALLHRQLDSASEC---ILYE--GCSGNTITRQALQRIRQAVT 3452
Query 3274 GKVEGCMVQVT-CGTTTLNGLWLD---------DVVYCPRHVICTSEDML---NPNYEDL 3320
V + + NG+ L +++ C H I TS+ Y+
Sbjct 3453 VVVTPASQNLCKITSNQANGIGLSCTGTFFTSTEIITCA-HGIGTSDITAVHKGITYDCK 3511
Query 3321 LIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 3380
+ +N ++ V L V + + + + FV Q ++
Sbjct 3512 VKSINNDIAILITTTVNLSVQNIKLDSSFSQKSDNYQRNFVQFVSFVDQQNSDAVTINN- 3570
Query 3381 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 3440
+ G GS + ++ + + G+H G D
Sbjct 3571 ---------TVMLPSGHFFAIGTEAGESGSP-YTLNGNII------------GIHYGIDN 3608
Query 3441 EGNFY------GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFN 3494
G++ G F T T + + A + A++ T+ N
Sbjct 3609 AGSWMLASRPDGSFYVPATQHGNSAKVTFSTDAFAQQFPAIV--------TNKTSDQLVN 3660
Query 3495 LVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEF 3554
+A N D D V + LK L N + L D
Sbjct 3661 EIAATNN-TAFELDTTD------------VSHLSNLLKHLKNNNETPK------SLSDYL 3701
Query 3555 TPFDVVRQCS---GVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAF 3611
V +Q S G T S V + +L++ + + + L N+
Sbjct 3702 PVAPVTQQTSVTVGQTLTSPVNNMQTALYTLMLVSEVITYI-------------LTPNSD 3748
Query 3612 LPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN-----MVYMPASWVMRIMTW 3666
L + + SAF K + L ++ T + + + + + + I+++
Sbjct 3749 LSVLISMFVTSAFLKFGAS-KLFYNTEMLRNTITTFVVYRYTTLLIALVFSQYYLHILSY 3807
Query 3667 LDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLV--YKVYYG 3724
++T + + V L+L+T R VY + + + +++ +
Sbjct 3808 ALKLNTLVLT-----VIALTFLVTPLVLLTIRRVYYYSQNYLISCVFIISCFASHTYTLY 3862
Query 3725 NALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYC 3784
D + IIS T + L G + V P++ C++ +Y
Sbjct 3863 ILTDTTVDFQTFIIS----EPIFSTLLCNLFIGFTLISVVPNPLYV-------CVVFMYI 3911
Query 3785 F-----LGYFCTCYFGLF 3797
LG+ TC+ +
Sbjct 3912 LLDCEALGFIVTCFMASY 3929
Score = 47.8 bits (112), Expect = 0.007, Method: Composition-based stats.
Identities = 35/159 (22%), Positives = 61/159 (38%), Gaps = 36/159 (23%)
Query 1046 VEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQV-----------ESDDYIATN 1094
+ + +VNAAN L +G GV GA+ A + +++ SD +
Sbjct 1657 IGAITTTEGEFIVNAANKQLNNGTGVTGAIFAAHDKELKLTQAIKALPTYGASDKLESHQ 1716
Query 1095 GPLKVGGSCVLSGHNL--AKHCLHVVGPNV----NKGEDIQL---------LKSAYENF- 1138
++ ++ +N A + LH P +K ++ L LK Y+
Sbjct 1717 HVVQT----IIKNNNSTHAINILHAAAPIKVKCTSKNPEVLLAHNETAQSELKETYKAIV 1772
Query 1139 -----NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTN 1172
N+ + PL AG +G P+ SL +D +R
Sbjct 1773 DYAQLNKLTHIYLPLFGAGAYGHKPLDSLEAFLDAMRNR 1811
Score = 37.7 bits (86), Expect = 7.0, Method: Composition-based stats.
Identities = 49/338 (14%), Positives = 90/338 (27%), Gaps = 59/338 (17%)
Query 2136 DTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTN--SRIKAS 2193
Y + +V Y+ F T T+ T + IKA
Sbjct 2554 SVFLAYIALLYSFSGHGIFTVVAYFTMLFARYYITSFINFCTSQLTATQVTQWFAAIKAK 2613
Query 2194 MPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALG-- 2251
+ + + + Y+ +S ++ + ++ ++ Y+
Sbjct 2614 YTGIYESSQDRVLTVNVTGTNVPYI--VKYSTILTVTMYVAFMAFVWTVSTYAAQYTAGE 2671
Query 2252 ---------VLMSNLGMPSYCTGYREGYLNSTNVTIATYCT--GSIPCSV-CLSGLDSLD 2299
V L + Y ++ + C SI C +
Sbjct 2672 RYDRPPYQTVFQKTLNVLGLTETVTYYYPYAS---LNEACAASTSILCRLGSPFNFHYPS 2728
Query 2300 TYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFI 2359
Y + T+Q SS W LF F L ++
Sbjct 2729 DYTQVRTVQTDTSSPFW----------------LFIIFMPPSFLFIVLPWLILCTITP-- 2770
Query 2360 SNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRAT 2419
+++ Q+ S ++ I F Y K H C TC+ +R+
Sbjct 2771 --------TVSIAQLLVPSIILNATIVF--IYIRRKFTGHC---CGPHTCIKHADISRSL 2817
Query 2420 RVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDT 2457
+ T+ + C HNW C N D+
Sbjct 2818 QFRPTSQIQHSLTFC-------GTLCAKHNWYCNNSDS 2848
>sp|Q9WQ77|R1AB_CVRSD Replicase polyprotein 1ab (Fragment) OS=Rat
coronavirus (strain 681) OX=33740 GN=rep PE=3 SV=1
Length=307
Score = 518 bits (1333), Expect = 1e-165, Method: Composition-based stats.
Identities = 225/307 (73%), Positives = 266/307 (87%), Gaps = 0/307 (0%)
Query 4898 FNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICST 4957
FNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI ST
Sbjct 1 FNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILST 60
Query 4958 MTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRA 5017
MT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPKCDRA
Sbjct 61 MTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPKCDRA 120
Query 5018 MPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDA 5077
MPN+LRI++SLVLARKH +CCS + RFYRLANECAQVLSE+VMCGG YVKPGGTSSGDA
Sbjct 121 MPNILRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLSEIVMCGGCYYVKPGGTSSGDA 180
Query 5078 TTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEF 5137
TTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD FV+E+
Sbjct 181 TTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVSEY 240
Query 5138 YAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDL 5197
Y +L KHFSMMILSDD VVC+NS +AS+G +A+I F+ VLYYQNNVFMSEAKCW ETD+
Sbjct 241 YEFLNKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQVLYYQNNVFMSEAKCWVETDI 300
Query 5198 TKGPHEF 5204
KGPHEF
Sbjct 301 EKGPHEF 307
>sp|Q9WQ76|R1AB_CVTMI Replicase polyprotein 1ab (Fragment) OS=Turkey
coronavirus (strain Minnesota) OX=231430 GN=rep PE=3
SV=1
Length=306
Score = 489 bits (1259), Expect = 7e-156, Method: Composition-based stats.
Identities = 213/307 (69%), Positives = 248/307 (81%), Gaps = 1/307 (0%)
Query 4898 FNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICST 4957
FNK+GKARLYY+ MS E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI ST
Sbjct 1 FNKFGKARLYYE-MSLEEQDQLFESTKKNVLPTITQMNLKYAISAKNRARTVAGVSILST 59
Query 4958 MTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRA 5017
MTNRQFHQK+LKSI TR A VVIGT+KFYGGW NML+ + VE+P LMGWDYPKCDRA
Sbjct 60 MTNRQFHQKILKSIVNTRNAPVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKCDRA 119
Query 5018 MPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDA 5077
MPN+LRI ASLVLARKHT CC+ S R YRL NECAQVLSE V+ G +YVKPGGTSSGDA
Sbjct 120 MPNLLRITASLVLARKHTNCCTWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSSGDA 179
Query 5078 TTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEF 5137
TTAYANSVFNI QA +ANV LLS I +++LQ+ LY+ +YR + D FV +F
Sbjct 180 TTAYANSVFNIIQATSANVARLLSVITRDIVYDDIKSLQYELYQQVYRRVNFDPAFVEKF 239
Query 5138 YAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDL 5197
Y+YL K+FS+MI +DD VVC+N+T A QGLVA I F+ +LYYQNNV+M+++KCW E DL
Sbjct 240 YSYLCKNFSLMIFADDGVVCYNNTLAKQGLVADISGFREILYYQNNVYMADSKCWVEPDL 299
Query 5198 TKGPHEF 5204
KGPHEF
Sbjct 300 EKGPHEF 306
>sp|P36697|R1AB_CVCAI Replicase polyprotein 1ab (Fragment) OS=Canine
coronavirus (strain Insavc-1) OX=36391 GN=rep PE=4 SV=1
Length=168
Score = 266 bits (680), Expect = 4e-80, Method: Composition-based stats.
Identities = 88/166 (53%), Positives = 119/166 (72%), Gaps = 2/166 (1%)
Query 6932 PKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAF 6991
P TK++ EN SK+GFFTY+ GFI++KL+LGGS AIKITE SWN DLY+L+ F +WT F
Sbjct 1 PNTKSIDGENTSKDGFFTYVNGFIKEKLSLGGSAAIKITEFSWNKDLYELIQRFEYWTVF 60
Query 6992 VTNVNASSSEAFLIGCNYLGK--PREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFP 7049
T+VN SSSE FLIG NYLG R +DG +MHANYIFWRN+ + LS S+ D KF
Sbjct 61 CTSVNTSSSEGFLIGVNYLGPYCDRAIVDGNIMHANYIFWRNSTIMALSHNSVLDTPKFK 120
Query 7050 LKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVN 7095
+ +++LKE ++N+M++ LL KG+L+IR N +++ + LVN
Sbjct 121 CRCNNALIVNLKEKELNEMVIGLLKKGKLLIRNNGKLLNFGNHLVN 166
>sp|Q04158|R1AB_CVPR8 Replicase polyprotein 1ab (Fragment) OS=Porcine
respiratory coronavirus (strain 86/137004 / isolate
British) OX=33736 GN=rep PE=4 SV=1
Length=131
Score = 211 bits (536), Expect = 2e-61, Method: Composition-based stats.
Identities = 60/130 (46%), Positives = 86/130 (66%), Gaps = 2/130 (2%)
Query 6969 ITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGK--PREQIDGYVMHANY 7026
ITE SWN LY+L+ F +WT F T+VN SSSE FLIG NYLG + +DG +MHANY
Sbjct 1 ITEFSWNKYLYELIQRFEYWTVFCTSVNTSSSEGFLIGVNYLGPYCDKAIVDGNIMHANY 60
Query 7027 IFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRV 7086
IFWRN+ + LS S+ D KF + +++LKE ++N+M++ LL KG+L+IR N ++
Sbjct 61 IFWRNSTIMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVIGLLRKGKLLIRNNGKL 120
Query 7087 VISSDVLVNN 7096
+ + +N
Sbjct 121 LNFGNHFINT 130
>sp|A7MG20|YMDB_CROS8 O-acetyl-ADP-ribose deacetylase OS=Cronobacter
sakazakii (strain ATCC BAA-894) OX=290339 GN=ymdB PE=3
SV=1
Length=180
Score = 190 bits (483), Expect = 1e-53, Method: Composition-based stats.
Identities = 49/183 (27%), Positives = 78/183 (43%), Gaps = 25/183 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
++ + + DI + V+VNAAN L GGGV GA+++A A+
Sbjct 1 MSGRINVVQGDIT----LIDVDVIVNAANPSLMGGGGVDGAIHRAAGPALLAACRQVRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGED--IQLLKSAYEN------FNQHEVL 1144
G + G + + +L AK +H VGP G+D QLL AY N N + +
Sbjct 57 QGECQPGHAVITEAGDLAAKAVVHTVGPVWRGGQDNEPQLLADAYRNSLQLVAANGYNSV 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSSFLE 1192
P +S GI+G + ++ +TV VY +D+ LY +L+ + E
Sbjct 117 AFPAISTGIYGYPKAAAAQIAFETVSDYLTRHPQPKQVYFVCYDEENFLLYQRLLGQYDE 176
Query 1193 MKS 1195
Sbjct 177 QPG 179
>sp|C9Y0V8|YMDB_CROTZ O-acetyl-ADP-ribose deacetylase OS=Cronobacter
turicensis (strain DSM 18703 / CCUG 55852 / LMG 23827
/ z3032) OX=693216 GN=ymdB PE=3 SV=1
Length=176
Score = 189 bits (479), Expect = 5e-53, Method: Composition-based stats.
Identities = 48/180 (27%), Positives = 78/180 (43%), Gaps = 25/180 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
++ + + DI ++ V+VNAAN L GGGV GA+++A ++
Sbjct 1 MSGRINVVQGDIT----RIDTDVIVNAANPSLMGGGGVDGAIHRAAGPSLLAACKVVRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGED--IQLLKSAYEN------FNQHEVL 1144
G + G + + +L AK +H VGP G D QLL AY N N + +
Sbjct 57 QGECQPGHAVITEAGDLAAKAVIHTVGPIWRGGHDNEPQLLADAYRNSLELVTANGYNSV 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSSFLE 1192
P +S GI+G + ++ +TV VY +D+ LY +L+ + E
Sbjct 117 AFPAISTGIYGYPKAAAAQIAFETVSDYLTRRPQPKQVYFVCYDEENFLLYQRLLGQYDE 176
>sp|B7LT90|YMDB_ESCF3 O-acetyl-ADP-ribose deacetylase OS=Escherichia
fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766
/ IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128
/ CDC 0568-73) OX=585054 GN=ymdB PE=3 SV=2
Length=177
Score = 184 bits (468), Expect = 1e-51, Method: Composition-based stats.
Identities = 46/177 (26%), Positives = 77/177 (44%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++ DI + + V+VNAAN L GGGV GA+++A +
Sbjct 1 MKSRIHVLQGDITQ----LAVDVIVNAANSSLMGGGGVDGAIHRAAGPELLEACQKVRRQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + NL A+ +H VGP GE + QLL AY N N ++ +
Sbjct 57 QGECPTGHAVITIAGNLPARAVIHTVGPVWRDGEHNEDQLLHDAYLNSLKLAQANGYKSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G++G + + V TV +Y +D+ LY++L++
Sbjct 117 AFPAISTGVYGFPRAAAAEIAVKTVSDFITRHALPEQIYFVCYDEENSRLYNRLLTQ 173
>sp|D2TT52|YMDB_CITRI O-acetyl-ADP-ribose deacetylase OS=Citrobacter
rodentium (strain ICC168) OX=637910 GN=ymdB PE=3 SV=2
Length=177
Score = 184 bits (468), Expect = 1e-51, Method: Composition-based stats.
Identities = 45/177 (25%), Positives = 76/177 (43%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++ + DI A +VNAAN L GGGV GA+++A +
Sbjct 1 MNSRIHVIHGDITTVA----VDAIVNAANPSLMGGGGVDGAIHRAAGPELLEACMTVRRQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + + L AK +H VGP GE + QLL AY N N ++ +
Sbjct 57 QGECPPGHAVITAAGRLPAKAVIHTVGPIWRGGEHNEAQLLHDAYLNSLNLALANGYQSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G++G + + V+T+ +Y +D+ LY +L++
Sbjct 117 AFPAISTGVYGYPRAAAAEIAVNTISEFITRRASPEQIYFVCYDEETTRLYQRLLTQ 173
>sp|B4T2X8|YMDB_SALNS O-acetyl-ADP-ribose deacetylase OS=Salmonella
newport (strain SL254) OX=423368 GN=ymdB PE=3 SV=1
Length=179
Score = 184 bits (467), Expect = 2e-51, Method: Composition-based stats.
Identities = 47/177 (27%), Positives = 75/177 (42%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T + + DI + + +VNAAN L GGGV GA+++A A+
Sbjct 1 MTSRLQVIQGDITQ----LSVDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G + G + + L AK +H VGP GE + +LL+ AY N N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRNCLLLAEANHFRSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G++G + + V TV VY +D+ LY +L++
Sbjct 117 AFPAISTGVYGYPRAQAAEIAVRTVSDFITRYALPEQVYFVCYDEETARLYARLLTQ 173
>sp|B5F961|YMDB_SALA4 O-acetyl-ADP-ribose deacetylase OS=Salmonella
agona (strain SL483) OX=454166 GN=ymdB PE=3 SV=1
Length=179
Score = 184 bits (467), Expect = 3e-51, Method: Composition-based stats.
Identities = 48/177 (27%), Positives = 76/177 (43%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T + + DI + + +VNAAN L GGGV GA+++A A+
Sbjct 1 MTSRLQVIQGDITQ----LSVDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G + G + + L AK +H VGP GE + +LL++AY N N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEYQEAELLEAAYRNCLLLAEANHFRSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G++G + V V TV VY +D+ LY +L++
Sbjct 117 AFPAISTGVYGYPRAQAAEVAVRTVSDFITRYALPEQVYFVCYDEETARLYARLLTQ 173
>sp|P67341|YMDB_SALTY O-acetyl-ADP-ribose deacetylase OS=Salmonella
typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287
GN=ymdB PE=3 SV=1
Length=179
Score = 184 bits (466), Expect = 3e-51, Method: Composition-based stats.
Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T + + DI + + +VNAAN L GGGV GA+++A A+
Sbjct 1 MTSRLQVIQGDITQ----LSVDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G + G + + L AK +H VGP GE + +LL+ AY N N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRNCLLLAEANHFRSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G++G + V V TV VY +D+ LY +L++
Sbjct 117 AFPAISTGVYGYPRAQAAEVAVRTVSDFITRYALPEQVYFVCYDEETARLYARLLTQ 173
>sp|P67342|YMDB_SALTI O-acetyl-ADP-ribose deacetylase OS=Salmonella
typhi OX=90370 GN=ymdB PE=3 SV=1
Length=179
Score = 184 bits (466), Expect = 3e-51, Method: Composition-based stats.
Identities = 48/177 (27%), Positives = 75/177 (42%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T + + DI + + +VNAAN L GGGV GA+++A A+
Sbjct 1 MTSRLQVIQGDITQ----LSVDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G + G + + L AK +H VGP GE + +LL+ AY N N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRNCLLLAEANHFRSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G++G + V V TV VY +D+ LY +L++
Sbjct 117 AFPAISTGVYGYPRAQAAEVAVRTVSDFITRYALPEQVYFVCYDEETARLYARLLTQ 173
>sp|B5RBF3|YMDB_SALG2 O-acetyl-ADP-ribose deacetylase OS=Salmonella
gallinarum (strain 287/91 / NCTC 13346) OX=550538 GN=ymdB
PE=3 SV=1
Length=179
Score = 182 bits (462), Expect = 1e-50, Method: Composition-based stats.
Identities = 47/177 (27%), Positives = 75/177 (42%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+T + + DI + + +VNAAN L GGGV GA+++A A+
Sbjct 1 MTSRLQVIQGDITQ----LSVDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G + G + + L AK +H VGP GE + +LL+ AY + N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRSCLLLAEANHFRSI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G++G + V V TV VY +D+ LY +L++
Sbjct 117 AFPAISTGVYGYPRAQAAEVAVRTVSDFITRYALPEQVYFVCYDEETARLYARLLTQ 173
>sp|A8AI35|YMDB_CITK8 O-acetyl-ADP-ribose deacetylase OS=Citrobacter
koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
OX=290338 GN=ymdB PE=3 SV=1
Length=177
Score = 182 bits (461), Expect = 2e-50, Method: Composition-based stats.
Identities = 47/177 (27%), Positives = 79/177 (45%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++++ DI + + V+VNAAN L GGGV GA+++A +
Sbjct 1 MKSRIHVQHGDITQ----LTVDVIVNAANASLLGGGGVDGAIHRAAGPTLLEACKKVRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + NL AK +H VGP G+ + QLL+ AY N N + +
Sbjct 57 QGECPAGHAVITLAGNLPAKAVIHTVGPVWRGGDHNESQLLEDAYFNSLQLVLANGYRSV 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G +G + + V+TV VY +D+ LY++L++
Sbjct 117 AFPAISTGAYGYPRPAAAEIAVNTVADFLARHALPEQVYFVCYDEETARLYERLLTQ 173
>sp|P0A8D6|YMDB_ECOLI O-acetyl-ADP-ribose deacetylase OS=Escherichia
coli (strain K12) OX=83333 GN=ymdB PE=1 SV=1
Length=177
Score = 181 bits (458), Expect = 3e-50, Method: Composition-based stats.
Identities = 48/177 (27%), Positives = 78/177 (44%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++ DI + + V+VNAAN L GGGV GA+++A A+
Sbjct 1 MKTRIHVVQGDITK----LAVDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + +L AK +H VGP GE + QLL+ AY N N + +
Sbjct 57 QGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSV 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G++G + + V TV VY +D+ LY++L++
Sbjct 117 AFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLTQ 173
>sp|P0A8D7|YMDB_ECOL6 O-acetyl-ADP-ribose deacetylase OS=Escherichia
coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) OX=199310
GN=ymdB PE=3 SV=1
Length=177
Score = 181 bits (458), Expect = 3e-50, Method: Composition-based stats.
Identities = 48/177 (27%), Positives = 78/177 (44%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++ DI + + V+VNAAN L GGGV GA+++A A+
Sbjct 1 MKTRIHVVQGDITK----LAVDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + +L AK +H VGP GE + QLL+ AY N N + +
Sbjct 57 QGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSV 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G++G + + V TV VY +D+ LY++L++
Sbjct 117 AFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLTQ 173
>sp|P0A8D8|YMDB_ECO57 O-acetyl-ADP-ribose deacetylase OS=Escherichia
coli O157:H7 OX=83334 GN=ymdB PE=3 SV=1
Length=177
Score = 181 bits (458), Expect = 3e-50, Method: Composition-based stats.
Identities = 48/177 (27%), Positives = 78/177 (44%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++ DI + + V+VNAAN L GGGV GA+++A A+
Sbjct 1 MKTRIHVVQGDITK----LAVDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + +L AK +H VGP GE + QLL+ AY N N + +
Sbjct 57 QGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSV 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G++G + + V TV VY +D+ LY++L++
Sbjct 117 AFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLTQ 173
>sp|Q0T5Z6|YMDB_SHIF8 O-acetyl-ADP-ribose deacetylase OS=Shigella
flexneri serotype 5b (strain 8401) OX=373384 GN=ymdB PE=3
SV=1
Length=177
Score = 179 bits (455), Expect = 9e-50, Method: Composition-based stats.
Identities = 47/177 (27%), Positives = 77/177 (44%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++ DI + + V+VNAAN L GGGV GA+++A A+
Sbjct 1 MKTRIHVVQGDITK----LAVDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + +L AK +H VGP GE + QLL+ AY N N + +
Sbjct 57 QGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSV 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G++ + + V TV VY +D+ LY++L++
Sbjct 117 AFPAISTGVYSYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLTQ 173
>sp|A4W960|YMDB_ENT38 O-acetyl-ADP-ribose deacetylase OS=Enterobacter
sp. (strain 638) OX=399742 GN=ymdB PE=3 SV=1
Length=180
Score = 176 bits (447), Expect = 1e-48, Method: Composition-based stats.
Identities = 47/175 (27%), Positives = 75/175 (43%), Gaps = 25/175 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ + + DI ++ V+VNAAN L GGGV GA+++A +
Sbjct 1 MKPQIEVVVGDIT----TMEVDVIVNAANPSLMGGGGVDGAIHRAAGPQLLEACKTVRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + +L AK +H VGP GE + + L+ AY N N ++ L
Sbjct 57 QGECAPGHAVITIAGDLPAKAVIHAVGPVWQGGENHEARTLQDAYLNCLRLAAANGYKTL 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLV 1187
P +S G++G + + VDTV VY +D+ LY +L+
Sbjct 117 AFPAISTGVYGYPKAAAAEIAVDTVSEFLTRKPLPERVYFVCYDEENAQLYQRLL 171
>sp|D5CE05|YMDB_ENTCC O-acetyl-ADP-ribose deacetylase OS=Enterobacter
cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054
/ NBRC 13535 / NCTC 10005 / WDCM 00083 / NCDC 279-56) OX=716541
GN=ymdB PE=3 SV=1
Length=180
Score = 176 bits (445), Expect = 2e-48, Method: Composition-based stats.
Identities = 45/177 (25%), Positives = 76/177 (43%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ + + + DI + V+VNAAN L GGGV GA+++A +
Sbjct 1 MKPQIDVIHGDIT----TMHVDVIVNAANPSLMGGGGVDGAIHRAAGPQLLEACKTVRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + +L AK +H VGP + G+ + +L+ AY N N ++ +
Sbjct 57 QGECPPGHAVITLAGDLPAKAVIHAVGPIWHGGDRHEASILEEAYRNCLRLAADNGYKTM 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G++G + + VDTV V FD+ LY +L++
Sbjct 117 AFPAISTGVYGYPKAAAATIAVDTVYRYLSLKPMPEKVTFVCFDEETLHLYQRLLTQ 173
>sp|Q32E73|YMDB_SHIDS O-acetyl-ADP-ribose deacetylase OS=Shigella
dysenteriae serotype 1 (strain Sd197) OX=300267 GN=ymdB
PE=3 SV=1
Length=177
Score = 175 bits (444), Expect = 3e-48, Method: Composition-based stats.
Identities = 46/177 (26%), Positives = 76/177 (43%), Gaps = 25/177 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +++ DI + + V+VN N L GGGV GA+++A A+
Sbjct 1 MKTRIHVVQGDITK----LAVDVIVNVTNPSLMGGGGVDGAIHRAAGPALLDACLKVRQQ 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVL 1144
G G + + +L AK +H VGP GE + QLL+ AY N N + +
Sbjct 57 QGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSV 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSS 1189
P +S G++G + + V TV VY +D+ LY++L++
Sbjct 117 AFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYDEENAHLYERLLTQ 173
>sp|P38859|DNA2_YEAST DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Saccharomyces cerevisiae (strain ATCC 204508
/ S288c) OX=559292 GN=DNA2 PE=1 SV=1
Length=1522
Score = 196 bits (498), Expect = 4e-48, Method: Composition-based stats.
Identities = 86/384 (22%), Positives = 136/384 (35%), Gaps = 82/384 (21%)
Query 5599 QKYSTLQGPPGTGKSHF--AIGLALYYPSARIVYTACSHAAVDALCEK-----------A 5645
+ Y+ + G PGTGK+ I L R++ T+ +H+AVD + K
Sbjct 1067 EDYALILGMPGTGKTTVIAEIIKILVSEGKRVLLTSYTHSAVDNILIKLRNTNISIMRLG 1126
Query 5646 LKYLPIDKCSRIIPARARVECFDKF--KVNSTLEQYVFCT-VN----ALPETTADIVVFD 5698
+K+ + +P A V+ ++ + K+NST C +N L E D V+ D
Sbjct 1127 MKHKVHPDTQKYVPNYASVKSYNDYLSKINSTSVVATTCLGINDILFTLNEKDFDYVILD 1186
Query 5699 EISMATNYDLSVVNARLRA-KHYVYIGDPAQLPA--PRTLLTKGTLEPEYFNSVCRLMKT 5755
E S + + V LR ++ +GD QLP G LE F + C
Sbjct 1187 EASQIS---MPVALGPLRYGNRFIMVGDHYQLPPLVKNDAARLGGLEESLFKTFCEKHPE 1243
Query 5756 IGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDK-----------------------S 5792
++ L R +IV + L+YDNKLK ++ S
Sbjct 1244 SVAELTL--QYRMCGDIVTLSNFLIYDNKLKCGNNEVFAQSLELPMPEALSRYRNESANS 1301
Query 5793 AQCFKMFYKGVITHDVSSAINRPQ-------------------IGVVREFLTRNPAWRKA 5833
Q + + + N P + V L
Sbjct 1302 KQWLEDILEPTRKVVFLNYDNCPDIIEQSEKDNITNHGEAELTLQCVEGMLLSGVPCEDI 1361
Query 5834 VFISPYNSQNAVASKIL------GLPTQTVDSSQGSEYDYVIF------TQTTETAHSCN 5881
++ Y +Q + KI GL T D QG + +I +Q A
Sbjct 1362 GVMTLYRAQLRLLKKIFNKNVYDGLEILTADQFQGRDKKCIIISMVRRNSQLNGGALLKE 1421
Query 5882 VNRFNVAITRAKVGILCIMSDRDL 5905
+ R NVA+TRAK ++ I S +
Sbjct 1422 LRRVNVAMTRAKSKLIIIGSKSTI 1445
>sp|D3RKJ0|YMDB_KLEVT O-acetyl-ADP-ribose deacetylase OS=Klebsiella
variicola (strain At-22) OX=640131 GN=ymdB PE=3 SV=1
Length=175
Score = 174 bits (441), Expect = 5e-48, Method: Composition-based stats.
Identities = 45/172 (26%), Positives = 75/172 (44%), Gaps = 25/172 (15%)
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKV 1099
+ DI ++ V+VNAAN L GGGV GA+++A A+ + G
Sbjct 7 VILGDIT----TLEVDVIVNAANPSLLGGGGVDGAIHRAAGPALLAACKQVLQQQGECPP 62
Query 1100 GGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVLLAPLLS 1150
G + + +L A +H VGP + G+ + Q L AY+N N + + P +S
Sbjct 63 GHAVITIAGDLPASAVIHTVGPVWHGGDRMEAQTLADAYKNSLQLAAANNYRSIAFPAIS 122
Query 1151 AGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSSF 1190
G++G + + V TV V FD+ +Y +L++S+
Sbjct 123 TGVYGYPKEEAAEIAVRTVTAFLTRYNPLERVLFVCFDEETAAIYRRLLASY 174
>sp|B5XXK9|YMDB_KLEP3 O-acetyl-ADP-ribose deacetylase OS=Klebsiella
pneumoniae (strain 342) OX=507522 GN=ymdB PE=3 SV=1
Length=175
Score = 174 bits (441), Expect = 5e-48, Method: Composition-based stats.
Identities = 45/172 (26%), Positives = 75/172 (44%), Gaps = 25/172 (15%)
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKV 1099
+ DI ++ V+VNAAN L GGGV GA+++A A+ + G
Sbjct 7 VILGDIT----TLEVDVIVNAANPSLLGGGGVDGAIHRAAGPALLAACKQVLQQQGECPP 62
Query 1100 GGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVLLAPLLS 1150
G + + +L A +H VGP + G+ + Q L AY+N N + + P +S
Sbjct 63 GHAVITIAGDLPASAVIHTVGPVWHGGDRMEAQTLADAYKNSLQLAAANNYRSIAFPAIS 122
Query 1151 AGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN---LYDKLVSSF 1190
G++G + + V TV V FD+ +Y +L++S+
Sbjct 123 TGVYGYPKEEAAEIAVRTVTAFLTRYNPLERVLFVCFDEETAAIYRRLLASY 174
>sp|B6SFA4|MAA3_ARATH Probable helicase MAGATAMA 3 OS=Arabidopsis
thaliana OX=3702 GN=MAA3 PE=2 SV=1
Length=818
Score = 189 bits (481), Expect = 3e-47, Method: Composition-based stats.
Identities = 69/256 (27%), Positives = 100/256 (39%), Gaps = 47/256 (18%)
Query 5692 ADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC- 5750
D+V+ DE + A +++ R K +GDP QLPA T+++ + Y S+
Sbjct 484 FDVVIIDEAAQAVE-PATLIPLATRCKQVFLVGDPKQLPA--TVISTVAQDSGYGTSMFE 540
Query 5751 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ--------------CF 5796
RL K P L T R EI S Y+ L+ D AQ CF
Sbjct 541 RLQKAGYPVKMLKTQYRMHPEIRSFPSKQFYEGALEDGSDIEAQTTRDWHKYRCFGPFCF 600
Query 5797 KMFYKGVITHD---VSSAINRPQIGVV----REFLTRNPAWRKA---VFISPYNSQ---- 5842
++G + S +N ++ V +T P + + ISPYN Q
Sbjct 601 FDIHEGKESQHPGATGSRVNLDEVEFVLLIYHRLVTMYPELKSSSQLAIISPYNYQVKTF 660
Query 5843 --------NAVASKILGLPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAI 5889
A K++ + TVD QG E D IF+ + + N R NV I
Sbjct 661 KDRFKEMFGTEAEKVVDI--NTVDGFQGREKDVAIFSCVRANENGQIGFLSNSRRMNVGI 718
Query 5890 TRAKVGILCIMSDRDL 5905
TRAK +L + S L
Sbjct 719 TRAKSSVLVVGSAATL 734
>sp|E1SDF1|YMDB1_PANVC O-acetyl-ADP-ribose deacetylase 1 OS=Pantoea
vagans (strain C9-1) OX=712898 GN=ymdB1 PE=3 SV=1
Length=171
Score = 172 bits (435), Expect = 4e-47, Method: Composition-based stats.
Identities = 47/171 (27%), Positives = 76/171 (44%), Gaps = 22/171 (13%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNG 1095
+ + DI + V +VNAAN L GGGV GA+++A + E G
Sbjct 2 KKITVIQGDITK----VSAEAIVNAANSSLLGGGGVDGAIHRAGGPVILAECQLIRNRQG 57
Query 1096 PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKG--EDIQLLKSAYEN------FNQHEVLLA 1146
KVG + + NL A + +H VGP + G ++ LLK AY++ ++ + +
Sbjct 58 GCKVGDAVITGAGNLPADYVIHTVGPRWSDGRHDEDALLKRAYQSCFKLVDYHGIKTVSF 117
Query 1147 PLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKNLYDKLVS 1188
P +S GI+G + + +D ++ NV L FD YD +
Sbjct 118 PNISTGIYGFPKERAATIALDVIKHCIAENRTLENVNLVCFDAENYDLYLK 168
>sp|Q8EYT0|Y4133_LEPIN Macro domain-containing protein LA_4133
OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar
Lai (strain 56601) OX=189518 GN=LA_4133 PE=4 SV=1
Length=175
Score = 167 bits (423), Expect = 2e-45, Method: Composition-based stats.
Identities = 44/178 (25%), Positives = 81/178 (46%), Gaps = 25/178 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ + + + DI + ++ +VNAAN L GGGV GA+++A + E
Sbjct 1 MNNKIKLIKEDITQ----LEVDAIVNAANSSLLGGGGVDGAIHRAGGPEILEECYKIREK 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKG--EDIQLLKSAYENF------NQHEVL 1144
G KVG + + + L AK +H VGP + G + +LL +AY+N + + +
Sbjct 57 QGECKVGEAVITTAGRLNAKFIIHTVGPIWSGGNKNEDELLSNAYKNSLLLAKNHSLKTI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVRT---------NVYLAVFD---KNLYDKLVSSF 1190
P +S GI+ + ++ + +V V+ FD +Y+KL+ ++
Sbjct 117 AFPNISTGIYHFPKERAAKIAIQSVTEFLKQDNQIQTVFFVCFDFENLEIYNKLLQTY 174
>sp|Q72M93|Y3295_LEPIC Macro domain-containing protein LIC_13295
OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar
copenhageni (strain Fiocruz L1-130) OX=267671 GN=LIC_13295
PE=4 SV=1
Length=175
Score = 167 bits (422), Expect = 2e-45, Method: Composition-based stats.
Identities = 44/178 (25%), Positives = 81/178 (46%), Gaps = 25/178 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ + + + DI + ++ +VNAAN L GGGV GA+++A + E
Sbjct 1 MNNKIKLIKEDITQ----LEVDAIVNAANSSLLGGGGVDGAIHRAGGPEILEECYKIREK 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKG--EDIQLLKSAYENF------NQHEVL 1144
G KVG + + + L AK +H VGP + G + +LL +AY+N + + +
Sbjct 57 QGECKVGEAVITTAGRLNAKFIIHTVGPIWSGGNKNEDELLSNAYKNSLLLAKNHSLKTI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVRT---------NVYLAVFD---KNLYDKLVSSF 1190
P +S GI+ + ++ + +V V+ FD +Y+KL+ ++
Sbjct 117 AFPNISTGIYHFPKERAAKIAIQSVTKFLKQDNQIQTVFFVCFDFENLEIYNKLLQTY 174
>sp|Q96XY5|Y2383_SULTO Uncharacterized protein STK_23830 OS=Sulfurisphaera
tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140
/ 7) OX=273063 GN=STK_23830 PE=4 SV=1
Length=182
Score = 164 bits (414), Expect = 3e-44, Method: Composition-based stats.
Identities = 53/184 (29%), Positives = 85/184 (46%), Gaps = 22/184 (12%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
V I DI E ++ +VNAAN YL+HGGGVA A+ + +Q ES +Y+ GP+
Sbjct 3 VKIIKGDITE----IEAEAIVNAANSYLEHGGGVARAIVEKGGYIIQKESREYVRKYGPV 58
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYENF------NQHEVLLAPLLS 1150
GG V S L AK+ +H VGP E + L+ A N + + P +S
Sbjct 59 PTGGVAVTSAGKLKAKYVIHAVGPRYGI-EGEEKLEEAIRNALRKAEELKLSSIALPAIS 117
Query 1151 AGIFGADPIHSLRVCVDTVRT---------NVYLAVFDKNLYDKLVSSF-LEMKSEKQVE 1200
GI+G V ++ + ++++ + Y+ V+ F E+ EK +
Sbjct 118 TGIYGYPYEICAEKMVKVIKEEYTNFKHLNTIIVSLYSEEAYNIFVNIFERELAKEKNIT 177
Query 1201 QKIA 1204
K++
Sbjct 178 LKMS 181
>sp|Q97UU4|Y2899_SACS2 Uncharacterized protein SSO2899 OS=Saccharolobus
solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322
/ P2) OX=273057 GN=SSO2899 PE=4 SV=1
Length=177
Score = 161 bits (407), Expect = 3e-43, Method: Composition-based stats.
Identities = 49/171 (29%), Positives = 83/171 (49%), Gaps = 17/171 (10%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
+Y+ DI E ++ +VNAAN YL+HGGGVA A+ + +Q ESD+Y+ GP+
Sbjct 10 IYLIKGDITE----IEADAIVNAANSYLQHGGGVAYAIVRKGGYIIQKESDEYVKKFGPV 65
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYENFNQHE-----VLLAPLLSA 1151
VG V S L AK+ +H VGP + +L + +++ + + + P +S
Sbjct 66 PVGEVAVTSAGKLKAKYVIHAVGPRYGIEGEDKLESAIFKSLLKADELSLSSIAMPAIST 125
Query 1152 GIFGADPIHSLRVCVDTVR-------TNVYLAVFDKNLYDKLVSSFLEMKS 1195
GI+G R+ + ++ V + ++ K+ YD S F +
Sbjct 126 GIYGYPFEICARIMANVLKGYKPKTLRKVMICLYTKDAYDVFKSIFNSILK 176
>sp|Q8ZXT3|Y1111_PYRAE Uncharacterized protein PAE1111 OS=Pyrobaculum
aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630
/ CIP 104966 / NBRC 100827 / IM2) OX=178306 GN=PAE1111 PE=4
SV=1
Length=182
Score = 159 bits (402), Expect = 2e-42, Method: Composition-based stats.
Identities = 51/169 (30%), Positives = 77/169 (46%), Gaps = 21/169 (12%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
V + DI E V+ +VNAAN YL+HGGGVAGA+ + +Q ES +++ +GP+
Sbjct 10 VVLMRGDITE----VEADAIVNAANSYLEHGGGVAGAIVRKGGQVIQEESREWVRKHGPV 65
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYENF------NQHEVLLAPLLS 1150
VG V S L AK+ +H VGP E I+ L A +N + P +S
Sbjct 66 PVGDVAVTSAGRLKAKYVIHAVGPRCG-VEPIEKLAEAVKNALLKAEELGLVSIALPAIS 124
Query 1151 AGIFGADPIHSLRVCVDTVRT---------NVYLAVFDKNLYDKLVSSF 1190
GIFG + +R + + ++ + Y K + F
Sbjct 125 TGIFGCPYDAAAEQMATAIREVAPALRSIRRILVVLYGEEAYQKFLEVF 173
>sp|Q8RB30|Y995_CALS4 Macro domain-containing protein TTE0995
OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain
DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=TTE0995
PE=4 SV=1
Length=175
Score = 158 bits (399), Expect = 3e-42, Method: Composition-based stats.
Identities = 43/179 (24%), Positives = 76/179 (42%), Gaps = 21/179 (12%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ + + + +IV++ + +VNAAN L GGGV GA++KA A+ E
Sbjct 1 MKEKIKLIKGNIVDQ----EVDAIVNAANSSLIGGGGVDGAIHKAGGPAIAEELKVIREK 56
Query 1094 NGPLKVGGSCVLSGHNL-AKHCLHVVGPNV--NKGEDIQLLKSAY----ENFNQH--EVL 1144
G G + + NL AK+ +H VGP + LL SAY + +++ + +
Sbjct 57 QGGCPTGHAVITGAGNLKAKYVIHAVGPIWKGGNHNEDNLLASAYIESLKLADEYNVKTI 116
Query 1145 LAPLLSAGIFGADPIHSLRVCVDTVR--------TNVYLAVFDKNLYDKLVSSFLEMKS 1195
P +S G +G + R+ + V V +F Y+ ++ E+
Sbjct 117 AFPSISTGAYGFPVERAARIALRVVSDYLEGSSIKEVRFVLFSDRDYEVYSKAYEELDK 175
>sp|E1PL40|YMDB2_PANVC O-acetyl-ADP-ribose deacetylase 2 OS=Pantoea
vagans (strain C9-1) OX=712898 GN=ymdB2 PE=3 SV=1
Length=171
Score = 156 bits (395), Expect = 9e-42, Method: Composition-based stats.
Identities = 44/171 (26%), Positives = 71/171 (42%), Gaps = 22/171 (13%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNG 1095
+ + + DI A ++N AN L GGGV GA+++A + E + G
Sbjct 2 NKITVIQGDITNIAS----EAIINVANSSLLGGGGVDGAIHRAGGPVILAECQAIRSRQG 57
Query 1096 PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKG---EDIQLLK---SAYENFNQH--EVLLA 1146
KVG + + L A + +H VGP + G ED QL S ++ H + +
Sbjct 58 GCKVGEAVITGAGTLPADYVIHTVGPRWSDGRHNEDTQLKSVYLSCFKLVGHHGIKTVSF 117
Query 1147 PLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKNLYDKLVS 1188
P +S GI+G + + +D ++ V L FD YD +
Sbjct 118 PNISTGIYGFPKKRAAAIALDVIKHCIAENRTIEKVNLVCFDAENYDLYLK 168
>sp|Q8TQD0|Y1614_METAC Macro domain-containing protein MA_1614
OS=Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834
/ JCM 12185 / C2A) OX=188937 GN=MA_1614 PE=4 SV=1
Length=195
Score = 154 bits (389), Expect = 1e-40, Method: Composition-based stats.
Identities = 50/202 (25%), Positives = 84/202 (42%), Gaps = 29/202 (14%)
Query 1014 MELTPVVQTIEVNSFSGYLKLTDN---VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGG 1070
P + ++ NS L ++ N + I DI E +K +VNAAN L GGG
Sbjct 2 DPQKPYKKELKRNSRKRSLNMSQNSERIRIIERDITE----LKVDAIVNAANNTLLGGGG 57
Query 1071 VAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--D 1127
V GA+++A + E NG G + + G+ L AK+ +H VGP +G +
Sbjct 58 VDGAIHRAAGPGLLEEC---RTLNG-CPTGEAKITKGYLLPAKYVIHTVGPIWQEGTKGE 113
Query 1128 IQLLKSAYEN----FNQHE--VLLAPLLSAGIFGADPIHSLRVCVDTVR---------TN 1172
+ L S Y +++ + P +S G +G + R+ V V+
Sbjct 114 DEFLASCYRKSLELARKYDVKTIAFPTISTGAYGFPSERAARIAVSQVKEFLKVNELPEI 173
Query 1173 VYLAVFDKNLYDKLVSSFLEMK 1194
V+L ++K + + E
Sbjct 174 VFLVCYNKEACKNIKKALEENL 195
>sp|Q4J9D2|Y1252_SULAC Uncharacterized protein Saci_1252 OS=Sulfolobus
acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929
/ NBRC 15157 / NCIMB 11770) OX=330779 GN=Saci_1252 PE=4
SV=1
Length=181
Score = 153 bits (387), Expect = 1e-40, Method: Composition-based stats.
Identities = 47/170 (28%), Positives = 77/170 (45%), Gaps = 17/170 (10%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
V ++N DI + V+ +VNAAN YL HGGGVA A+ ++ +Q ESD+Y+ NGP+
Sbjct 13 VILENGDITK----VEADAIVNAANSYLSHGGGVALAIVRSGGYIIQEESDEYVRRNGPV 68
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYENFNQHE-----VLLAPLLSA 1151
VG V + L A++ +H VGP D +L + + + + + P +S
Sbjct 69 PVGEVAVTTAGKLKARYVIHAVGPRYGIEGDDKLESAIRRSLEKADELKLSSIALPAIST 128
Query 1152 GIFGADPIHSLRVCVDTVRT-------NVYLAVFDKNLYDKLVSSFLEMK 1194
GI+G R+ ++ + + V+ Y F
Sbjct 129 GIYGYPYEICARIMSKVMKEYKPKFLKRILVVVYGDQAYSVFKKVFDNSL 178
>sp|Q8Q0F9|Y177_METMA Macro domain-containing protein MM_0177
OS=Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1
/ Go1 / JCM 11833 / OCM 88) OX=192952 GN=MM_0177 PE=4 SV=1
Length=187
Score = 153 bits (387), Expect = 1e-40, Method: Composition-based stats.
Identities = 48/164 (29%), Positives = 75/164 (46%), Gaps = 26/164 (16%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNG 1095
D + I DIV+ ++ +VNAAN L GGGV GA+++A A+ E NG
Sbjct 19 DRIRIFEGDIVK----MRVDAIVNAANNTLLGGGGVDGAIHRAAGPALLEECK---TLNG 71
Query 1096 PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVLLA 1146
G + + SG+ L AK+ +H VGP GE + +LL S Y + + +
Sbjct 72 -CPTGEAKITSGYLLPAKYIIHTVGPVWQGGEKGEDELLASCYRKSLELARDYKIKTIAF 130
Query 1147 PLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKN 1181
P +S G +G + + V V+ VYL ++K+
Sbjct 131 PAISTGAYGFPSERAAGIAVSQVKEFLQKNEIPETVYLVCYNKD 174
>sp|Q92355|SEN1_SCHPO Helicase sen1 OS=Schizosaccharomyces pombe
(strain 972 / ATCC 24843) OX=284812 GN=sen1 PE=1 SV=1
Length=1687
Score = 171 bits (433), Expect = 2e-40, Method: Composition-based stats.
Identities = 66/255 (26%), Positives = 103/255 (40%), Gaps = 43/255 (17%)
Query 5690 TTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV 5749
V+ DE + A D +++ R AK + +GDP QLP T+L+K Y S+
Sbjct 1370 LNFSTVIIDEAAQAVELD-TIIPLRYGAKKCILVGDPNQLPP--TVLSKKAASLNYSQSL 1426
Query 5750 C-RLMKTIGPDM-FLGTCRRCPAEIVDTVSALVYDNKLKA------------HKDKSAQC 5795
R+ K M L R +I S YD++L+ H +
Sbjct 1427 FVRIQKNFSNQMCLLSIQYRMHPDISHFPSKKFYDSRLEDGDNMAEKTQQVWHVNPKFTQ 1486
Query 5796 FKMF-YKGV-ITHDVSSAINRPQIG----VVREFLTRNP----AWRKAVFISPYNSQNAV 5845
+++F +G T + S N ++ +V E L + P R V I+PY SQ
Sbjct 1487 YRLFDVRGKERTSNTMSTYNLEEVEYLVNMVDELLNKFPDVNFTGRIGV-ITPYRSQLHE 1545
Query 5846 ASK----------ILGLPTQTVDSSQGSEYDYVIF-TQTTETAHSC----NVNRFNVAIT 5890
+ + + QTVD QG E D + F + + H + R NVA+T
Sbjct 1546 LRRAFKVKYGKSFMSTIDIQTVDGFQGQEKDIIFFSCVKSYSKHGIGFLRDFRRLNVALT 1605
Query 5891 RAKVGILCIMSDRDL 5905
RA+ +L I + L
Sbjct 1606 RARSSLLIIGNMETL 1620
Score = 43.5 bits (101), Expect = 0.11, Method: Composition-based stats.
Identities = 20/84 (24%), Positives = 35/84 (42%), Gaps = 20/84 (24%)
Query 5601 YSTLQGPPGTGKSHFAIGLALY--------------------YPSARIVYTACSHAAVDA 5640
++ +QGPPGTGK+ IG+ +I+ A S+AAVD
Sbjct 1147 FTLIQGPPGTGKTKTIIGIISALLVDLSRYHITRPNQQSKSTESKQQILLCAPSNAAVDE 1206
Query 5641 LCEKALKYLPIDKCSRIIPARARV 5664
+ + + ++ + IP R+
Sbjct 1207 VLLRLKRGFLLENGEKYIPRVVRI 1230
>sp|Q8KAE4|Y2219_CHLTE Macro domain-containing protein CT2219
OS=Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC
103806 / TLS) OX=194439 GN=CT2219 PE=4 SV=1
Length=172
Score = 147 bits (372), Expect = 1e-38, Method: Composition-based stats.
Identities = 44/172 (26%), Positives = 71/172 (41%), Gaps = 29/172 (17%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
++ ADI + +VNAAN L GGGV GA+++A + + G
Sbjct 7 IHAIKADITS----LTVDAIVNAANTSLLGGGGVDGAIHRAAGPKLLEACREL----GGC 58
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYENFNQ------HEVLLAPL 1148
G + + G+ L A +H VGP + G + +LL S Y N + + P
Sbjct 59 LTGEAKITKGYRLPATFVIHTVGPVWHGGNHGEAELLASCYRNSLKLAIEHHCRTIAFPS 118
Query 1149 LSAGIFGADPIHSLRVCVDTVR---------TNVYLAVF---DKNLYDKLVS 1188
+S GI+G + + + TVR V F D ++Y K ++
Sbjct 119 ISTGIYGYPVEQAAAIAITTVREMLADERGIEKVIFCCFSDRDLDVYQKALA 170
>sp|Q9WYX8|Y508_THEMA Uncharacterized protein TM_0508 OS=Thermotoga
maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC
100826 / MSB8) OX=243274 GN=TM_0508 PE=3 SV=1
Length=599
Score = 155 bits (391), Expect = 6e-37, Method: Composition-based stats.
Identities = 49/144 (34%), Positives = 70/144 (49%), Gaps = 13/144 (9%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNG 1095
+ I DI E + +VNAAN YLKHGGGVAGA+ +A + +Q ESD + G
Sbjct 427 KKIRIVKGDITRE----EVDAIVNAANEYLKHGGGVAGAIVRAGGSVIQEESDRIVQERG 482
Query 1096 PLKVGGSCVLSGHNL-AKHCLHVVGPNVNK---GEDIQLLKSAYENF-----NQHEVLLA 1146
+ G + V S L AK+ +H VGP GED L K+ Y + + +
Sbjct 483 RVPTGEAVVTSAGKLKAKYVIHTVGPVWRGGSHGEDELLYKAVYNALLRAHELKLKSISM 542
Query 1147 PLLSAGIFGADPIHSLRVCVDTVR 1170
P +S GIFG ++ + +R
Sbjct 543 PAISTGIFGFPKERAVGIFSKAIR 566
>sp|Q8Y3S3|Y2759_LISMO Macro domain-containing protein lmo2759
OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679
/ EGD-e) OX=169963 GN=lmo2759 PE=4 SV=1
Length=176
Score = 142 bits (357), Expect = 1e-36, Method: Composition-based stats.
Identities = 49/175 (28%), Positives = 75/175 (43%), Gaps = 27/175 (15%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
+ I DI E+ + V+VNAAN L GGGV GA+++A + E + I G
Sbjct 3 ITIVKGDITEQ----EVDVIVNAANSGLLGGGGVDGAIHQAAGPDLLKECQEVINRIGSC 58
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAY------ENFNQHEVLLAPL 1148
G + + S +L A + +H VGP GE + L S Y + P
Sbjct 59 PAGEAVITSAGDLKATYIIHAVGPIWKDGEHQEANKLASCYWKALDLAAGKDLTSIAFPN 118
Query 1149 LSAGIFGADPIHSLRVCVDTVR-----------TNVYLAVFDKN---LYDKLVSS 1189
+S G++G + V + TVR + FD+ LY+KL++S
Sbjct 119 ISTGVYGFPKKLAAEVALYTVRKWAEEEYDTSIKEIRFVCFDEENLKLYNKLINS 173
>sp|Q71W03|Y2748_LISMF Macro domain-containing protein LMOf2365_2748
OS=Listeria monocytogenes serotype 4b (strain F2365)
OX=265669 GN=LMOf2365_2748 PE=4 SV=1
Length=176
Score = 141 bits (356), Expect = 2e-36, Method: Composition-based stats.
Identities = 48/175 (27%), Positives = 75/175 (43%), Gaps = 27/175 (15%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
+ + DI E+ V+VNAAN L GGGV GA+++A + E + I G
Sbjct 3 ITVVKGDITEQ----DVDVIVNAANPGLLGGGGVDGAIHQAAGPDLLKECQEVINRIGTC 58
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAY------ENFNQHEVLLAPL 1148
G + + S +L A + +H VGP GE + L S Y + + P
Sbjct 59 PAGEAVITSAGDLQASYIIHAVGPIWKDGEHQEANKLASCYWKALDLAAGKELTSIAFPN 118
Query 1149 LSAGIFGADPIHSLRVCVDTVR-----------TNVYLAVFDKN---LYDKLVSS 1189
+S G++G + V + TVR + FD+ LY+KL++S
Sbjct 119 ISTGVYGFPKKLAAEVALYTVRKWAEEEYDTSIEEIRFVCFDEENLKLYNKLINS 173
>sp|Q87JZ5|Y4103_VIBPA Macro domain-containing protein VPA0103
OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
OX=223926 GN=VPA0103 PE=4 SV=1
Length=170
Score = 141 bits (355), Expect = 2e-36, Method: Composition-based stats.
Identities = 41/155 (26%), Positives = 68/155 (44%), Gaps = 14/155 (9%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNG-P 1096
+ + DI +VNAAN + GGGV GA+++A A+ +G
Sbjct 4 ISLVQGDIT----TAHVDAIVNAANPRMLGGGGVDGAIHRAAGPALINACYAVDDVDGIR 59
Query 1097 LKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ-LLKSAYEN------FNQHEVLLAPL 1148
G + + NL A++ +H VGP +K D + +L+SAY+ N + + P
Sbjct 60 CPFGDARITEAGNLNARYVIHAVGPIYDKFADPKTVLESAYQRSLDLALANHCQSVALPA 119
Query 1149 LSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLY 1183
+S G++G P + V + + Y A D Y
Sbjct 120 ISCGVYGYPPQEAAEVAMAVCQRPEY-AALDMRFY 153
>sp|Q926Y8|Y2902_LISIN Macro domain-containing protein lin2902
OS=Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP
11262) OX=272626 GN=lin2902 PE=4 SV=1
Length=176
Score = 141 bits (355), Expect = 2e-36, Method: Composition-based stats.
Identities = 49/176 (28%), Positives = 74/176 (42%), Gaps = 27/176 (15%)
Query 1037 NVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGP 1096
++ + DI E+ V+VNAAN L GGGV GA+++A + E + I G
Sbjct 2 DITVVKGDITEQ----NVDVIVNAANPGLLGGGGVDGAIHQAAGPDLLKECQEVINRIGS 57
Query 1097 LKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAY------ENFNQHEVLLAP 1147
G + + S +L A +H VGP GE + L S Y + P
Sbjct 58 CPAGEAVITSAGDLKAHFIIHAVGPIWKDGEHQEANKLASCYWKALDLAAGKDLTSIAFP 117
Query 1148 LLSAGIFGADPIHSLRVCVDTVR-----------TNVYLAVFDKN---LYDKLVSS 1189
+S G++G + V + TVR V FD+ LY+KL++S
Sbjct 118 NISTGVYGFPKKLAAEVALYTVRKWAEEEYDSSIKEVRFVCFDEENLTLYNKLINS 173
>sp|Q7MTZ7|MACRO_PORGI Macro domain-containing protein PG1779
OS=Porphyromonas gingivalis (strain ATCC BAA-308 / W83) OX=242619
GN=PG_1779 PE=2 SV=1
Length=164
Score = 140 bits (352), Expect = 4e-36, Method: Composition-based stats.
Identities = 41/170 (24%), Positives = 73/170 (43%), Gaps = 24/170 (14%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNG 1095
+ I DI + + +VNAAN L GGGV GA+++A + E NG
Sbjct 2 GKITITVGDIT----RFEGDAIVNAANHTLLGGGGVDGAIHRAAGPELLEEC---RTLNG 54
Query 1096 PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN------FNQHEVLLA 1146
G S + G+NL A++ +H VGP + G+ + +LL S Y + +
Sbjct 55 -CPTGESKITGGYNLPAQYVIHTVGPVWHGGQHGEPELLASCYRTSLSIALDKGLKSIAF 113
Query 1147 PLLSAGIFGADPIHSLRVCVDTVRT-------NVYLAVFDKNLYDKLVSS 1189
P +S G++ + R+ + T+ +V + F + + ++
Sbjct 114 PCISTGVYRYPKDQAARIALATIGEIIADRPIDVTIVCFSEADKEFYITQ 163
>sp|Q9HXU7|Y3693_PSEAE Macro domain-containing protein PA3693
OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP
104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964
GN=PA3693 PE=4 SV=1
Length=173
Score = 137 bits (346), Expect = 4e-35, Method: Composition-based stats.
Identities = 44/180 (24%), Positives = 73/180 (41%), Gaps = 30/180 (17%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
V + DI ++ +VNAAN L GGGV GA+++A + +G
Sbjct 4 VRVWQGDIT----RLAVDAIVNAANSSLLGGGGVDGAIHRAAGAELVAAC---RLLHG-C 55
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYENFN------QHEVLLAPL 1148
K G + + G L A H +H VGP G+ + +LL S Y + P
Sbjct 56 KTGEAKITRGFRLPAAHVIHTVGPVWRGGDNGEAELLASCYRRSLALAEQAGAASVAFPA 115
Query 1149 LSAGIFGADPIHSLRVCVDTV---------RTNVYLAVFDKNLYDKLVSSFLEMKSEKQV 1199
+S GI+G + + V+ V + L FD ++ ++ + + E+ V
Sbjct 116 ISCGIYGYPLEQAAAIAVEEVCRQRPAHSSLEEIVLVAFDSSMAER----YQRLLGERPV 171
>sp|Q9ZBG3|Y6450_STRCO Macro domain-containing protein SCO6450
OS=Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
OX=100226 GN=SCO6450 PE=4 SV=1
Length=169
Score = 136 bits (342), Expect = 1e-34, Method: Composition-based stats.
Identities = 42/167 (25%), Positives = 68/167 (41%), Gaps = 20/167 (12%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATN--G 1095
+ + DI + +VNAAN L GGGV GA+++ A+ E A +
Sbjct 4 ITLVQGDITRQ----SADAIVNAANSSLLGGGGVDGAIHRRGGPAILAECRRLRAGHLGK 59
Query 1096 PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ-LLKSAYENF------NQHEVLLAP 1147
L G + + +L A+ +H VGP + ED LL S Y + P
Sbjct 60 GLPTGRAVATTAGDLDARWVIHTVGPVWSATEDRSGLLASCYRESLRTADELGARTVAFP 119
Query 1148 LLSAGIFGADPIHSLRVCVDTVRTN------VYLAVFDKNLYDKLVS 1188
+S G++ + R+ V+TV T + +FD Y+ +
Sbjct 120 AISTGVYRWPMDDAARIAVETVATTKTSVTEIRFVLFDARAYEAFAA 166
>sp|Q93SX7|Y189_ACISE Macro domain-containing protein OS=Acinetobacter
sp. (strain ED45-25) OX=194927 PE=4 SV=1
Length=183
Score = 136 bits (343), Expect = 1e-34, Method: Composition-based stats.
Identities = 42/179 (23%), Positives = 68/179 (38%), Gaps = 22/179 (12%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNG 1095
V++ ADI +VN+AN L GGG+ ++K M+ E G
Sbjct 2 KKVHLIQADIT----AFAVHAIVNSANKSLLGGGGLDYVIHKKAGPLMKEECVRLNQEKG 57
Query 1096 PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYENFN------QHEVLLA 1146
G + V + NL AK+ +H VGP GE + QLL AY N +
Sbjct 58 GCPTGQAEVTTAGNLPAKYLIHAVGPRWLDGEHNEPQLLCDAYSNALFKANEIHALTVSF 117
Query 1147 PLLSAGIFGADPIHSLRVCVDTVRT---------NVYLAVFDKNLYDKLVSSFLEMKSE 1196
P +S G++G P + + + T+ + V+ + Y + +
Sbjct 118 PCISTGVYGFPPQKAAEIAIGTILSMLPQYDHVAEVFFICREDENYLIYKNILSNIDDP 176
>sp|Q8Y2K1|Y334_RALN1 Macro domain-containing protein RSc0334
OS=Ralstonia nicotianae (strain GMI1000) OX=267608 GN=RSc0334
PE=4 SV=1
Length=171
Score = 136 bits (342), Expect = 1e-34, Method: Composition-based stats.
Identities = 43/159 (27%), Positives = 72/159 (45%), Gaps = 22/159 (14%)
Query 1048 EAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSG 1107
+ + +VNAAN L GGGV GA+++A + A +G + G + + G
Sbjct 14 DITTLACDAIVNAANSALLGGGGVDGAIHRAAGPELLEAC---RALHG-CRTGQAKITPG 69
Query 1108 HNL-AKHCLHVVGPNVNKG--EDIQLLKSAYEN----FNQHE--VLLAPLLSAGIFGADP 1158
L A++ +H VGP G ++ LL + Y N QH+ + P +S G++G P
Sbjct 70 FLLPARYIIHTVGPIWRGGRQDEAALLAACYRNSLALAKQHDVRTIAFPCISTGVYGFPP 129
Query 1159 IHSLRVCVDTVRT------NVYLAVF---DKNLYDKLVS 1188
+ + V TVR ++ F D LY+ ++
Sbjct 130 QLAAPIAVRTVREHGADLDDIVFCCFSAADLALYETALN 168
>sp|Q9KHE2|Y189_STRGR Macro domain-containing protein in non 5'region
OS=Streptomyces griseus OX=1911 PE=4 SV=1
Length=177
Score = 136 bits (342), Expect = 1e-34, Method: Composition-based stats.
Identities = 43/177 (24%), Positives = 68/177 (38%), Gaps = 21/177 (12%)
Query 1031 YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDY 1090
++ V + DI ++ V+VNAAN L GGGV GA+++ + +
Sbjct 2 STSVSPVVRLVRGDITDQ----SVDVIVNAANSSLLGGGGVDGAIHRRGGPDILAACREL 57
Query 1091 IATN--GPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGED-IQLLKSAYE------NFNQ 1140
A+ L G + + L A+ +H VGP + +D LL S Y
Sbjct 58 RASRYGKGLPTGQAVATTAGRLDARWIVHTVGPVFSGAQDRSALLASCYRESLRLAAELG 117
Query 1141 HEVLLAPLLSAGIFGADPIHSLRVCVDTV-------RTNVYLAVFDKNLYDKLVSSF 1190
+ P +S GI+G R+ V TV V +FD + Y +
Sbjct 118 ARSIAFPAISTGIYGWPMDDGARIAVRTVLAETVEPVEEVRFVLFDAHAYVEFEEVL 174
>sp|Q8P5Z8|Y3184_XANCP Macro domain-containing protein XCC3184
OS=Xanthomonas campestris pv. campestris (strain ATCC 33913
/ DSM 3586 / NCPPB 528 / LMG 568 / P 25) OX=190485 GN=XCC3184
PE=4 SV=1
Length=179
Score = 135 bits (340), Expect = 2e-34, Method: Composition-based stats.
Identities = 38/167 (23%), Positives = 66/167 (40%), Gaps = 24/167 (14%)
Query 1037 NVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDY--IATN 1094
+ + DI + + V+VNAAN L GGGV GA+++A + + +
Sbjct 2 RIEVWQGDITQ----LDVDVIVNAANESLLGGGGVDGAIHRAAGPRLLEACEALPEVRPG 57
Query 1095 GPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHE------VLL 1145
G + G +L A+H H VGP G + + L + Y + +
Sbjct 58 VRCPTGEIRITDGFDLKARHIFHTVGPVWRDGKHNEPEQLANCYWQSLKLAEQMMLHSIA 117
Query 1146 APLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKNLY 1183
P +S GI+G + R+ V R ++ L +++ Y
Sbjct 118 FPAISCGIYGYPLYQAARIAVTETRDWQRSHKVPKHIVLVAYNEATY 164
>sp|Q8PHB6|Y3343_XANAC Macro domain-containing protein XAC3343
OS=Xanthomonas axonopodis pv. citri (strain 306) OX=190486
GN=XAC3343 PE=4 SV=2
Length=179
Score = 135 bits (340), Expect = 3e-34, Method: Composition-based stats.
Identities = 39/167 (23%), Positives = 66/167 (40%), Gaps = 24/167 (14%)
Query 1037 NVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDY--IATN 1094
+ + DI E + V+VNAAN L GGGV GA+++A + + +
Sbjct 2 RIEVWQGDITE----LDVDVIVNAANESLLGGGGVDGAIHRAAGPRLLEACEALPQVRPG 57
Query 1095 GPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKG--EDIQLLKSAYENFNQHE------VLL 1145
G + G +L A+H H VGP G + + L + Y + +
Sbjct 58 VRCPTGEIRITDGFDLKARHIFHTVGPVWRDGRHNEPEQLANCYWQSLKLAEQMMLHSIA 117
Query 1146 APLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKNLY 1183
P +S GI+G + R+ V R ++ L +++ Y
Sbjct 118 FPAISCGIYGYPLHQAARIAVTETRDWQRSHKVPKHIVLVAYNEATY 164
>sp|Q44020|YGB2_CUPNE Macro domain-containing protein in gbd 3'region
OS=Cupriavidus necator OX=106590 PE=4 SV=1
Length=173
Score = 134 bits (338), Expect = 4e-34, Method: Composition-based stats.
Identities = 43/166 (26%), Positives = 73/166 (44%), Gaps = 22/166 (13%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNG 1095
+++ + + DI +++ +VNAAN L GGGV GA++ A +A++ T G
Sbjct 4 EHLQVVHGDIT----RMEVDAIVNAANSGLLGGGGVDGAIHGAGGSAIKEACRAIRDTQG 59
Query 1096 PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYENF------NQHEVLLA 1146
G + + +G +L A + +H VGP G+ + +LL +AY N + L
Sbjct 60 GCPTGEAVITTGGHLPAPYVIHAVGPVWQGGDQGEDELLANAYRNSIRLAAQHHLRRLAF 119
Query 1147 PLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKNLY 1183
P +S GI+ + + + VR V FD Y
Sbjct 120 PNISTGIYAFPRERAADIAIAAVREALAAAPEIEQVTFVCFDDENY 165
>sp|Q88SK6|Y3408_LACPL Macro domain-containing protein lp_3408
OS=Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB
8826 / WCFS1) OX=220668 GN=lp_3408 PE=4 SV=1
Length=172
Score = 134 bits (337), Expect = 6e-34, Method: Composition-based stats.
Identities = 38/170 (22%), Positives = 72/170 (42%), Gaps = 27/170 (16%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
+ + + DI + + +VNAAN L GGGV GA+++A A+ +G
Sbjct 4 IKVIHGDITK----MTVDAIVNAANTSLLGGGGVDGAIHRAAGPALLAAC---RPLHG-C 55
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYENF------NQHEVLLAPL 1148
G + + G L AK+ +H GP G+ ++QLL ++Y N N + + P
Sbjct 56 ATGEAKITPGFRLPAKYVIHTPGPVWQGGQHNELQLLANSYRNSLNLAAENHCQTVAFPS 115
Query 1149 LSAGIFGADPIHSLRVCVDTVRT----------NVYLAVFDKNLYDKLVS 1188
+S G++ + + + T++ + + FD + +
Sbjct 116 ISTGVYHFPLSIAAPLALKTLQATAQTTAHTVQTITIVCFDDQTQNVFST 165
>sp|Q8RHQ2|Y1951_FUSNN Uncharacterized protein FN1951 OS=Fusobacterium
nucleatum subsp. nucleatum (strain ATCC 25586 / DSM
15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG
13131 / VPI 4355) OX=190304 GN=FN1951 PE=4 SV=1
Length=175
Score = 134 bits (337), Expect = 6e-34, Method: Composition-based stats.
Identities = 43/171 (25%), Positives = 75/171 (44%), Gaps = 25/171 (15%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
+ + + DI + + +VNAAN L+ GGGV GA+ KA + + E + G
Sbjct 6 IKLISGDITKIP---EVEAIVNAANSSLEMGGGVCGAIFKAAGSELAQECKEI----GGC 58
Query 1098 KVGGSCVLSGHNLA-KHCLHVVGPNVNKGE--DIQLLKSAY----ENFNQHEV--LLAPL 1148
G + + G+NL K+ +H VGP + GE + + L SAY + N+ + + P
Sbjct 59 NTGEAVITKGYNLPNKYIIHTVGPRYSTGENREAERLASAYYESLKLANEKGIRRIAFPS 118
Query 1149 LSAGIFGADPIHSLRVCVDTVRT---------NVYLAVFDKNLYDKLVSSF 1190
+S GI+ ++ + T ++ L V D+ Y +
Sbjct 119 ISTGIYRFPVDEGAKIALTTAIKFLDKNPSSFDLILWVLDEKTYIVYKEKY 169
>sp|Q6PAV8|MACD2_XENLA ADP-ribose glycohydrolase MACROD2 OS=Xenopus
laevis OX=8355 GN=macrod2 PE=2 SV=1
Length=418
Score = 140 bits (354), Expect = 1e-33, Method: Composition-based stats.
Identities = 58/273 (21%), Positives = 104/273 (38%), Gaps = 35/273 (13%)
Query 1007 EVQPQLEMELTPVVQTIEVNSFSGYLK--LTDNVYIKNADIVEEAKKVKPTVVVNAANVY 1064
+ P L EL + + + +K L + V DI + ++ +VNAAN
Sbjct 37 DKIPSLMEELKSKASSDDESPEEIQVKNSLCEKVSFYKGDITQ----LEVDAIVNAANTS 92
Query 1065 LKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVN 1123
L GGGV G +++A+ ++ E + G + G + + G+ L AK+ +H VGP
Sbjct 93 LLGGGGVDGCIHRASGPSLLAECREL----GGCETGQAKITCGYELPAKYVIHTVGPIAR 148
Query 1124 KG---EDIQLLKSAYENF------NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT--- 1171
Q L S Y + N + P +S GI+G + V + TV+
Sbjct 149 GHITPNHKQDLASCYNSSLTLATENDIRTIAFPCISTGIYGYPNEPAANVALTTVKEFLK 208
Query 1172 -------NVYLAVFDK---NLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPS 1221
V VF + +Y + ++ F + +++ + +E+K S
Sbjct 209 KNRDKIDRVIFCVFLEVDFKIYKRKLNEFF--PKDGGDDEEGEKGDSDEMKEDTEGKPQS 266
Query 1222 VEQRKQDDKKIKACVEEVTTTLEETKFLTENLL 1254
+K +KK + + T N
Sbjct 267 PPMKKIKEKKEDTPAPDSPDEEYSAEEATGNTQ 299
>sp|Q9EYI6|Y189_STRNO Macro domain-containing protein in sno 5'region
OS=Streptomyces nogalater OX=38314 PE=4 SV=1
Length=181
Score = 132 bits (333), Expect = 2e-33, Method: Composition-based stats.
Identities = 46/165 (28%), Positives = 69/165 (42%), Gaps = 20/165 (12%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI-ATNGP 1096
+ + DI + +VNAAN L GGGV GA+++ A+ E + G
Sbjct 4 ITLVQGDITRQ----HADALVNAANSSLLGGGGVDGAIHRRGGPAILAECRALRASRYGE 59
Query 1097 -LKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ-LLKSAYENF------NQHEVLLAP 1147
L G + + +L A+ +H VGP + ED LL S Y + P
Sbjct 60 GLPTGRAVATTAGDLDARWVIHTVGPVWSSTEDRSDLLASCYRESLRLAGELGARTVAFP 119
Query 1148 LLSAGIFGADPIHSLRVCVDTVRTN------VYLAVFDKNLYDKL 1186
LS G++ + R+ V+TVRT V +FD + YD
Sbjct 120 ALSTGVYRWPMGDAARIAVETVRTTPTAVEEVRFVLFDTHAYDTF 164
>sp|Q97AU0|Y719_THEVO Uncharacterized protein TV0719 OS=Thermoplasma
volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 /
NBRC 15438 / GSS1) OX=273116 GN=TV0719 PE=4 SV=1
Length=186
Score = 132 bits (333), Expect = 3e-33, Method: Composition-based stats.
Identities = 43/169 (25%), Positives = 69/169 (41%), Gaps = 22/169 (13%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGP- 1096
+ I DI + V +VNAAN L GGGV GA++ + +E + T P
Sbjct 11 IEIIEGDITD----VNCEAIVNAANPSLMGGGGVDGAIHLKGGKTIDLECAELRRTKWPK 66
Query 1097 -LKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ--LLKSAYEN-----FNQHEVLLAP 1147
L G + + SG L AK+ +H VGP E+ L S Y + + + + P
Sbjct 67 GLPPGEADITSGGKLKAKYVIHTVGPIYRGQEEDAETLYSSYYRSLEIAKIHGIKCIAFP 126
Query 1148 LLSAGIFGADPIHSLRVCVDTVRT--------NVYLAVFDKNLYDKLVS 1188
+S GI+G + + + V + ++ + Y VS
Sbjct 127 AISTGIYGYPFEEASVIALKAVTDFLSNKEGYIIKFVLYGQARYQTFVS 175
>sp|Q985D2|Y7730_RHILO Macro domain-containing protein mll7730
OS=Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 /
MAFF 303099) OX=266835 GN=mll7730 PE=4 SV=1
Length=176
Score = 130 bits (328), Expect = 1e-32, Method: Composition-based stats.
Identities = 51/182 (28%), Positives = 78/182 (43%), Gaps = 29/182 (16%)
Query 1033 KLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIA 1092
K D + I DI + + +VNAAN L GGGV GA+++A ++VE
Sbjct 3 KALDRIRIHTGDITK----LDVDAIVNAANTLLLGGGGVDGAIHRAAGRELEVEC---RM 55
Query 1093 TNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKG--EDIQLLKSAYE------NFNQHEV 1143
NG KVG + + G+ L A+H +H VGP G + +LL S Y N
Sbjct 56 LNG-CKVGDAKITKGYKLPARHIIHTVGPVWQGGGKGEAELLASCYRSSLELAAANDCRS 114
Query 1144 LLAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDK---NLYDKLVSSFL 1191
+ P +S G++ + + V TV V FD+ LY + V++
Sbjct 115 VAFPAISTGVYRYPKDEATGIAVGTVSMVIEEKAMPETVIFCCFDEQTAQLYLRAVAALR 174
Query 1192 EM 1193
+
Sbjct 175 KG 176
>sp|Q3UYG8|MACD2_MOUSE ADP-ribose glycohydrolase MACROD2 OS=Mus
musculus OX=10090 GN=Macrod2 PE=1 SV=1
Length=475
Score = 138 bits (347), Expect = 4e-32, Method: Composition-based stats.
Identities = 70/389 (18%), Positives = 137/389 (35%), Gaps = 63/389 (16%)
Query 1003 QTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAAN 1062
+ ++ + Q + E T ++ + L++ V + DI ++ +VNAAN
Sbjct 44 KEEMKSKGQNDEENTQEAPQMKKS-------LSEKVSLYRGDIT----LLEVDAIVNAAN 92
Query 1063 VYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPN 1121
L GGGV G +++A + E NG + G + + G++L AK+ +H VGP
Sbjct 93 ASLLGGGGVDGCIHRAAGPCLLAEC---RNLNG-CETGHAKITCGYDLPAKYVIHTVGPI 148
Query 1122 VNK---GEDIQLLKSAYENF------NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT- 1171
G + L + Y++ N + P +S GI+G + + + T++
Sbjct 149 ARGHINGSHKEDLANCYQSSLKLVKENNLRSVAFPCISTGIYGFPNEPAAVIALGTIKEW 208
Query 1172 ---------NVYLAVFDK---NLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITES- 1218
+ VF + +Y K ++ F + + + E +P
Sbjct 209 LAKNHQEVDRIIFCVFLEVDFKIYKKKMNEFFPVDDNNEGTDADMKEDSEGPEPKGLSPP 268
Query 1219 -KPSVEQRK---------QDDKKIKACVEEVTTTLEET---KFLTENLLLYIDING---- 1261
K S ++ + + K EE+ +E +FL NLL I +G
Sbjct 269 HKKSKAKKPESSKDSSEDESGPEEKQTAEEMEGQSQEAGGLRFLLRNLLGLIHRDGVNTT 328
Query 1262 ---NLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTA-VVIPTKKAGGTTEMLAKAL 1317
+ + V + + V D +P + + + K
Sbjct 329 PVPSPASEDKAEVHKDEDS---AKDDNTVKDSDMTNHSVCDQELPNGQENDSAKSEGKTE 385
Query 1318 RKVPTDNYITTYPGQGLNGYTVEEAKTVL 1346
+ P+ + T + E V+
Sbjct 386 AESPSSSMETEDLSPNQEDAAIVEQPEVI 414
>sp|Q8K4G6|MACD1_RAT ADP-ribose glycohydrolase MACROD1 (Fragment)
OS=Rattus norvegicus OX=10116 GN=Macrod1 PE=2 SV=2
Length=258
Score = 131 bits (330), Expect = 6e-32, Method: Composition-based stats.
Identities = 44/220 (20%), Positives = 85/220 (39%), Gaps = 18/220 (8%)
Query 962 FGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQ 1021
+ + A + + DW + S E++ ++ P + +
Sbjct 11 WAPLAMAAKVDLSTSTDWKEAKSFLKGLSDKQREEHYFCKDFIKLKKIPMWKETAKGLAG 70
Query 1022 TIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNN 1081
+E + +L + + + DI + ++ +VNAAN L GGGV G +++A +
Sbjct 71 KVENPKYKKDKQLNEKISLFRGDITK----LEVDAIVNAANNSLLGGGGVDGCIHRAAGS 126
Query 1082 AMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKG---EDIQLLKSAYEN 1137
+ E + G + + G+ L AKH +H VGP L+S Y +
Sbjct 127 LLTDECRTLQN----CETGKAKITCGYRLPAKHVIHTVGPIAVGQPTASQAAELRSCYLS 182
Query 1138 F------NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
++ + P +S G+FG + V + T+R
Sbjct 183 SLDLLLEHRLRSVAFPCISTGVFGYPNEEAAEVVLATLRE 222
>sp|A1Z1Q3|MACD2_HUMAN ADP-ribose glycohydrolase MACROD2 OS=Homo
sapiens OX=9606 GN=MACROD2 PE=1 SV=2
Length=425
Score = 135 bits (340), Expect = 1e-31, Method: Composition-based stats.
Identities = 68/325 (21%), Positives = 128/325 (39%), Gaps = 36/325 (11%)
Query 997 NQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTV 1056
N + + ++ + Q + E T ++ + LT+ V + DI ++
Sbjct 38 NSILSWKEEMKGKGQNDEENTQETSQVKKS-------LTEKVSLYRGDIT----LLEVDA 86
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCL 1115
+VNAAN L GGGV G +++A + E NG G + + G++L AK+ +
Sbjct 87 IVNAANASLLGGGGVDGCIHRAAGPCLLAEC---RNLNG-CDTGHAKITCGYDLPAKYVI 142
Query 1116 HVVGPNVNK---GEDIQLLKSAYENF------NQHEVLLAPLLSAGIFGADPIHSLRVCV 1166
H VGP G + L + Y++ N + P +S GI+G + + +
Sbjct 143 HTVGPIARGHINGSHKEDLANCYKSSLKLVKENNIRSVAFPCISTGIYGFPNEPAAVIAL 202
Query 1167 DTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRK 1226
+T++ +LA + + FLE+ K ++K+ E + E E
Sbjct 203 NTIKE--WLAKNHHEVDRIIFCVFLEVD-FKIYKKKMNEFFSVDDNNEEEEDVEMKEDSD 259
Query 1227 QDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYI 1286
++ + K VEE+ ++ + + + + G P S V D KD
Sbjct 260 ENGPEEKQSVEEMEEQSQDA-----DGVNTVTVPG---PASEEAVEDCKDEDFAKDENIT 311
Query 1287 VGDVVQEGVLTAVVIPTKKAGGTTE 1311
G V + + P + +T+
Sbjct 312 KGGEVTDHSVRDQDHPDGQENDSTK 336
>sp|Q9BQ69|MACD1_HUMAN ADP-ribose glycohydrolase MACROD1 OS=Homo
sapiens OX=9606 GN=MACROD1 PE=1 SV=2
Length=325
Score = 132 bits (331), Expect = 2e-31, Method: Composition-based stats.
Identities = 44/220 (20%), Positives = 86/220 (39%), Gaps = 18/220 (8%)
Query 962 FGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQ 1021
+ + A + + DW + S E++ ++ P + V
Sbjct 78 WAPLAMAAKVDLSTSTDWKEAKSFLKGLSDKQREEHYFCKDFVRLKKIPTWKEMAKGVAV 137
Query 1022 TIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNN 1081
+E + +L + + + +DI + ++ +VNAAN L GGGV G +++A
Sbjct 138 KVEEPRYKKDKQLNEKISLLRSDITK----LEVDAIVNAANSSLLGGGGVDGCIHRAAGP 193
Query 1082 AMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNK---GEDIQLLKSAYEN 1137
+ E + K G + + G+ L AK+ +H VGP L+S Y +
Sbjct 194 LLTDECRTLQS----CKTGKAKITGGYRLPAKYVIHTVGPIAYGEPSASQAAELRSCYLS 249
Query 1138 F------NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
++ + P +S G+FG + + + T+R
Sbjct 250 SLDLLLEHRLRSVAFPCISTGVFGYPCEAAAEIVLATLRE 289
>sp|Q922B1|MACD1_MOUSE ADP-ribose glycohydrolase MACROD1 OS=Mus
musculus OX=10090 GN=Macrod1 PE=1 SV=2
Length=323
Score = 131 bits (330), Expect = 3e-31, Method: Composition-based stats.
Identities = 42/220 (19%), Positives = 85/220 (39%), Gaps = 18/220 (8%)
Query 962 FGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQ 1021
+ + A + + DW + S E++ ++ P + +
Sbjct 76 WAPLAMAAKVDLSTSTDWKEAKSFLKGLSDKQREEHYFCKDFIKLKKIPTWKETAKGLAV 135
Query 1022 TIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNN 1081
+E + +L + + + DI + ++ +VNAAN L GGGV G +++A +
Sbjct 136 KVEDPKYKKDKQLNEKISLYRGDITK----LEVDAIVNAANSSLLGGGGVDGCIHRAAGS 191
Query 1082 AMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKG---EDIQLLKSAYEN 1137
+ E + G + + G+ L AK+ +H VGP L+S Y +
Sbjct 192 LLTDECRTLQN----CETGKAKITCGYRLPAKYVIHTVGPIAVGQPTASQAAELRSCYLS 247
Query 1138 F------NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
++ + P +S G+FG + V + ++R
Sbjct 248 SLDLLLEHRLRSVAFPCISTGVFGYPNEEAAEVVLASLRE 287
>sp|Q2KHU5|MACD1_BOVIN ADP-ribose glycohydrolase MACROD1 OS=Bos
taurus OX=9913 GN=MACROD1 PE=2 SV=1
Length=325
Score = 130 bits (328), Expect = 6e-31, Method: Composition-based stats.
Identities = 43/220 (20%), Positives = 83/220 (38%), Gaps = 18/220 (8%)
Query 962 FGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQ 1021
+ + A + + DW + S E++ ++ P + V
Sbjct 78 WAPLAMAAKVDLSTSTDWKEAKSFLKGLSDKQREEHYFCRDFVRLKKIPTWKETAKGVTV 137
Query 1022 TIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNN 1081
+E + +L + + + DI + ++ +VNAAN L GGGV G +++A
Sbjct 138 KVEEPKYKKDKQLNEKISLFRGDITK----LEVDAIVNAANSSLLGGGGVDGCIHRAAGP 193
Query 1082 AMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNK---GEDIQLLKSAYEN 1137
+ E + G + + G+ L AK+ +H VGP + L+S Y +
Sbjct 194 LLTDECRTLQN----CETGKAKITCGYRLPAKYVIHTVGPIAHGEPSASQAAELRSCYLS 249
Query 1138 F------NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
++ P +S G+FG + V + +R
Sbjct 250 SLDLLLEHRLRSAAFPCISTGVFGYPNEAAAEVVLTALRE 289
>sp|Q9RS39|Y2288_DEIRA Macro domain-containing protein DR_2288
OS=Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 /
JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279
/ VKM B-1422 / R1) OX=243230 GN=DR_2288 PE=4 SV=1
Length=170
Score = 125 bits (314), Expect = 6e-31, Method: Composition-based stats.
Identities = 35/176 (20%), Positives = 69/176 (39%), Gaps = 31/176 (18%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
+ + DI + VV AAN L GGGV G +++A + I G
Sbjct 3 LELVQGDIAHQ----PVDAVVTAANKQLMGGGGVDGVIHRAAGPRLLQA----IRPIGGT 54
Query 1098 KVGGSCVLSGHNL----AKHCLHVVGPNVNKGE--DIQLLKSAYENF------NQHEVLL 1145
G + + +L K+ +H VGP G+ + +LL AY N +
Sbjct 55 PTGTAVITPAFDLERQGVKYVIHAVGPIWRGGQHGEAELLAGAYRESLRLGVENGCRSVA 114
Query 1146 APLLSAGIFGADPIHSLRVCVDTV--------RTNVYLAVFDKN---LYDKLVSSF 1190
P +S G++G + + + T+ +V + ++ + ++++ ++
Sbjct 115 FPSISTGVYGYPLDRAAPIALATIQDFLRSHPDLSVRMVLYGADALHVFERALAQL 170
>sp|Q2EMV9|PAR14_MOUSE Protein mono-ADP-ribosyltransferase PARP14
OS=Mus musculus OX=10090 GN=Parp14 PE=1 SV=3
Length=1817
Score = 138 bits (348), Expect = 1e-30, Method: Composition-based stats.
Identities = 62/273 (23%), Positives = 96/273 (35%), Gaps = 34/273 (12%)
Query 1034 LTDNVYIKNADIV---------EEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQ 1084
+ + DI E+ + VVVNAAN LKH G+A AL+KA +Q
Sbjct 798 INEQKCHLQRDIAPGVKLFVLEEDLSRFPVDVVVNAANENLKHISGLAQALSKAAGPELQ 857
Query 1085 VESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKG---EDIQLLKSAYENFNQ 1140
E D + G + G + + L H +H VGP E + LLK
Sbjct 858 TECDQIVKEGGVVLPGNAVISKAGKLPCHHVIHAVGPRWKGDKVLECVSLLKKVVRQSLS 917
Query 1141 ------HEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMK 1194
+ P +SAGIF L +CV + + + K L +L
Sbjct 918 LAEEHRCRSIAMPAVSAGIFDFP----LELCVANIVSAIKEHFQHKRDTHTLKKIYLVGL 973
Query 1195 SEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFL--TEN 1252
+V + AE K K ++ + +KA V T ++ L E
Sbjct 974 -PAKVARAFAEAVKTTYKDSLSHTAF--------PSSLKALVPLGKTPQKQGSLLVSPEG 1024
Query 1253 LLLYIDINGNLHPDSATLVSDIDITFLKKDAPY 1285
L + + G + + +V+ I P
Sbjct 1025 LRIRLVEEGVQNATTHAIVNSISPDLKLNKGPL 1057
Score = 62.4 bits (150), Expect = 2e-07, Method: Composition-based stats.
Identities = 50/327 (15%), Positives = 104/327 (32%), Gaps = 49/327 (15%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
+ +I++E V+VN+ + GV+ A+ + ++ E +
Sbjct 1240 FQVATGNIIKEV----ADVIVNSTTLTFDLKSGVSKAILEGAGQNVEQECSLLAKQSN-- 1293
Query 1098 KVGGSCVLSGHNL--AKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFG 1155
+++G L K+ +HVVG N K +L+ + + + P + G
Sbjct 1294 ---HGYIVTGGGLLQCKNIIHVVGGNDVKKSVSCVLEECEQ--RNYSSICLPAIGTGNAQ 1348
Query 1156 ADPIHSLRVCVDTVRT-----------NVYLAVFDKNLYDKLVSSFLEMKSE-------- 1196
DP + +D + V + +F ++ + E +
Sbjct 1349 QDPNVVAKAIIDAIEEFVQKKSVQAVKRVKVVIFQPHILQFFYDNMKEREGSPAPPKQSP 1408
Query 1197 -KQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLL 1255
KQ K + V ++K + + C V + + +L E +
Sbjct 1409 AKQSVMSKIASFLGFPKQASPKKNTLVLEKKIEHTVFQVCGSGVDSVNKTISWLKELITK 1468
Query 1256 YIDINGNLHPDSATLVSDIDITFLKKDAPYIVG------------DVVQEGVLTAVVIPT 1303
+ + VSD D+ +K + G+ V+
Sbjct 1469 ----EQLSYTNDDECVSDFDMEEYEKLNEIQKELNITIEMNQKKTSIQVSGISRDVIKAR 1524
Query 1304 KKAGGTTEMLAKALRKVPTDNYITTYP 1330
+ G + + A K +YI+TY
Sbjct 1525 DEIEGMIKSIRLAKEKESQADYISTYV 1551
Score = 57.8 bits (138), Expect = 5e-06, Method: Composition-based stats.
Identities = 55/407 (14%), Positives = 117/407 (29%), Gaps = 55/407 (14%)
Query 1015 ELTPVVQTIEVNSFSGYLKLTD---NVYIKNADIVEEAKKVKPTVVVNAANVYLK-HGGG 1070
L +V + G L ++ + + E + +VN+ + LK + G
Sbjct 1001 SLKALVPLGKTPQKQGSLLVSPEGLRIRLVE----EGVQNATTHAIVNSISPDLKLNKGP 1056
Query 1071 VAGALNKATNNAMQVESDDYIATNG-PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDI 1128
++ A + +Q E + G + VG SG NL ++H HVV P
Sbjct 1057 LSQAFLEKAGPKLQEELT--RSGQGVSVDVGTILQTSGCNLNSRHVFHVVPPPWKSNNSA 1114
Query 1129 QLLKSAYENFNQH---------EVLLAPLLSAGIFGADPIHSLRVCVDTVRT-------- 1171
LK + + P + G ++ + V
Sbjct 1115 WSLKIMKNIIRDCLKTTENLSLQSIAFPAIGTGNLRFPKPEFAKLIISEVLKFSSRNQLK 1174
Query 1172 -----NVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPS----- 1221
L D F + + ++ + + ++
Sbjct 1175 TLQEVQFLLHPKDHENIQAFSDEFDKRNNGDPSDKNPKAEDTQGIYGSLSSPTLGMHEMN 1234
Query 1222 ---VEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDITF 1278
+ + IK + + + T L + I L + + +
Sbjct 1235 IGPILFQVATGNIIKEVADVIVNSTTLTFDLKSGVSKAI-----LEGAGQNVEQECSLLA 1289
Query 1279 LKKDAPYIV--GDVVQEGVLTAVVIPTKKAGGTTEMLAKALRK------VPTDNYITTYP 1330
+ + YIV G ++Q + VV + +L + ++ +P
Sbjct 1290 KQSNHGYIVTGGGLLQCKNIIHVVGGNDVKKSVSCVLEECEQRNYSSICLPAIGTGNAQQ 1349
Query 1331 GQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLRE 1377
+ + +A + KS + + + IL N++E
Sbjct 1350 DPNVVAKAIIDAIEEFVQKKSVQAVKRVKVVIFQPHILQFFYDNMKE 1396
>sp|Q8CAS9|PARP9_MOUSE Protein mono-ADP-ribosyltransferase PARP9
OS=Mus musculus OX=10090 GN=Parp9 PE=1 SV=2
Length=866
Score = 137 bits (344), Expect = 2e-30, Method: Composition-based stats.
Identities = 50/172 (29%), Positives = 71/172 (41%), Gaps = 17/172 (10%)
Query 1047 EEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLS 1106
++ + VVNAAN L HG G+AG+L K +Q ES IA G + VGG +
Sbjct 127 DDLTRHVVDAVVNAANENLLHGSGLAGSLVKTGGFEIQEESKRIIANVGKISVGGIAITG 186
Query 1107 GHNLAKH-CLHVVGPNV---NKGEDIQLLKSAYENFNQH--------EVLLAPLLSAGIF 1154
L H +H VGP N I+LLK A N + + + P LS+GIF
Sbjct 187 AGRLPCHLIIHAVGPRWTVTNSQTAIELLKFAIRNILDYVTKYDLRIKTVAIPALSSGIF 246
Query 1155 GADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEI 1206
L +C + + L DK ++ L L + +E
Sbjct 247 QFP----LDLCTSIILETIRLYFQDKQMFGNLREIHL-VSNEDPTVASFKSA 293
Score = 40.8 bits (94), Expect = 0.68, Method: Composition-based stats.
Identities = 28/174 (16%), Positives = 59/174 (34%), Gaps = 24/174 (14%)
Query 1055 TVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKH 1113
V+VN+ + G VA ++ + M+ E D + +V V G L ++
Sbjct 339 DVIVNSGYMQDFKSGRVAQSILRQAGVEMEKELDKVNLSTDYQEV---WVTKGFKLSCQY 395
Query 1114 CLHVVGPNVNKGEDIQLLKSAYENFNQH------EVLLAPLLSAGIFGADPIHSLRVCVD 1167
HV ++ Q+LK A ++ + + P L G+ + ++ +
Sbjct 396 VFHVA--WHSQINKYQILKDAMKSCLEKCLKPDINSISFPALGTGLMDLKKSTAAQIMFE 453
Query 1168 TV----------RTNVYLAVF--DKNLYDKLVSSFLEMKSEKQVEQKIAEIPKE 1209
V V + +F D Y + + +E + + +
Sbjct 454 EVFAFAKEHKEKTLTVKIVIFPVDVETYKIFYAEMTKRSNELNLSGNSGALALQ 507
>sp|O94387|YGSA_SCHPO Uncharacterized ATP-dependent helicase C29A10.10c
OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
OX=284812 GN=SPBC29A10.10c PE=3 SV=1
Length=1944
Score = 138 bits (347), Expect = 2e-30, Method: Composition-based stats.
Identities = 69/307 (22%), Positives = 118/307 (38%), Gaps = 45/307 (15%)
Query 5690 TTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV 5749
T V+ DE + A S++ + + V +GDP QLP T+L+K + + Y S+
Sbjct 1508 LTFRTVIIDEAAQAVELS-SIIPLKYGCESCVMVGDPNQLPP--TVLSKTSAKFGYSQSL 1564
Query 5750 CRLM--KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQC------------ 5795
M + L R EI S Y++KL + SA
Sbjct 1565 YVRMFKQHNESACLLSIQYRMNPEISRFPSKFFYNSKLLDGPNMSAVTSRPWHEDPQLGI 1624
Query 5796 --FKMFYKGVITHDVSSAINRPQIGV--------VREFLTRNPAWRKAVFISPYNSQ--- 5842
F + + S N + ++ +L + + V ++PY SQ
Sbjct 1625 YRFFNVHGTEAFSNSKSLYNVEEASFILLLYERLIQCYLNIDFEGKIGV-VTPYRSQVQQ 1683
Query 5843 -NAVASKILG------LPTQTVDSSQGSEYDYVIF-----TQTTETAHSCNVNRFNVAIT 5890
+ + G L TVD QG E D +IF + + ++ R NVA+T
Sbjct 1684 LRSQFQRKYGSIIFKHLDIHTVDGFQGQEKDIIIFSCVRSSMSGGIGFLQDLRRLNVALT 1743
Query 5891 RAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPT 5950
RAK + + + + L + F SL I + + FK+ SK I+ + A
Sbjct 1744 RAKSSLYIVGNSKPLMQEDIFYSL-IEDAKTRGVWRDLSANQFKN-SKSISNVSTHLASN 1801
Query 5951 HLSVDTK 5957
+L++ ++
Sbjct 1802 NLNLASR 1808
Score = 39.7 bits (91), Expect = 1.4, Method: Composition-based stats.
Identities = 23/124 (19%), Positives = 44/124 (35%), Gaps = 24/124 (19%)
Query 5560 SAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGL 5619
P+ + +I Y +N ++ Y ++ +QGPPGTGK+ +G+
Sbjct 1252 RLPSNFTDDKKQKIMKSY-GVNEPQAYA----IYASSVNDGFTLIQGPPGTGKTKTILGM 1306
Query 5620 ALY-------------------YPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPA 5660
+I+ A S+AA+D + + + + + P
Sbjct 1307 IGAVLTSSSQGLQFNVPGQTRKTSKNKILICAPSNAAIDEILLRIKAGVYDHEGIKFFPK 1366
Query 5661 RARV 5664
RV
Sbjct 1367 VIRV 1370
>sp|Q460N5|PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14
OS=Homo sapiens OX=9606 GN=PARP14 PE=1 SV=3
Length=1801
Score = 137 bits (346), Expect = 3e-30, Method: Composition-based stats.
Identities = 47/173 (27%), Positives = 75/173 (43%), Gaps = 18/173 (10%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
+ ++ D ++ VVVNA+N LKH GG+A AL+KA +Q + D + G L
Sbjct 804 LIVQQGD----LARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRL 859
Query 1098 KVGGSCVLSGHNLA-KHCLHVVGPNVNKGED---IQLLKSAYE------NFNQHEVLLAP 1147
G + + L H +H VGP + E + LL+ A + ++ + P
Sbjct 860 LPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIP 919
Query 1148 LLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVE 1200
+S+G+FG + V ++ N K L +L SEK VE
Sbjct 920 AISSGVFGFPLGRCVETIVSAIKENFQF----KKDGHCLKEIYLVDVSEKTVE 968
Score = 67.0 bits (162), Expect = 8e-09, Method: Composition-based stats.
Identities = 35/219 (16%), Positives = 73/219 (33%), Gaps = 26/219 (12%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
+ + DI +E + V+VN+ + GV+ A+ + ++ E
Sbjct 1229 FQVASGDITKE----EADVIVNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRK-- 1282
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGA 1156
+ G L K+ +HV+G N K +L+ + + + P + G
Sbjct 1283 --NDYIITGGGFLRCKNIIHVIGGNDVKSSVSSVLQECEK--KNYSSICLPAIGTGNAKQ 1338
Query 1157 DPIHSLRVCVDTVR-----------TNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAE 1205
P +D + V + +F + D ++ + + + Q+
Sbjct 1339 HPDKVAEAIIDAIEDFVQKGSAQSVKKVKVVIFLPQVLDVFYANMKKREGTQLSSQQSVM 1398
Query 1206 IPKEEVKPFITES----KPSVEQRKQDDKKIKACVEEVT 1240
F +S V ++K + + C E VT
Sbjct 1399 SKLASFLGFSKQSPQKKNHLVLEKKTESATFRVCGENVT 1437
Score = 64.3 bits (155), Expect = 5e-08, Method: Composition-based stats.
Identities = 67/418 (16%), Positives = 122/418 (29%), Gaps = 56/418 (13%)
Query 1045 IVEEAKKVKPTVVVNAANVYL-KHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSC 1103
+ E + K VVVN+ + L G ++ +L + +Q E D + + +G
Sbjct 1019 VKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDT-VGQGVAVSMGTVL 1077
Query 1104 VLSGHNL-AKHCLHVVGPNVNKG--------EDIQLLKSAYENFNQHEVLLAPLLSAGIF 1154
S NL ++ LHVV P G EDI + + P + G
Sbjct 1078 KTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNL 1137
Query 1155 GADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPF 1214
G + + V+ L FL S+ + Q ++
Sbjct 1138 GFPKNIFAELIIS----EVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFARRANGN 1193
Query 1215 ITESKPSVEQRKQDDKKIKACVEEVTTTLEETK--------FLTENLLLYIDINGNLHPD 1266
+ K + Q V + + E K + D+ N +
Sbjct 1194 LVSDKIPKAKDTQG---FYGTVSSPDSGVYEMKIGSIIFQVASGDITKEEADVIVNSTSN 1250
Query 1267 SATLVSDIDITFLKKDAPYIVGDVVQE-------------GVLTAVVIPTKKAGGTT-EM 1312
S L + + L+ + + Q+ G L I G
Sbjct 1251 SFNLKAGVSKAILECAGQNVERECSQQAQQRKNDYIITGGGFLRCKNIIHVIGGNDVKSS 1310
Query 1313 LAKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVS 1372
++ L++ NY + G AK K A I V
Sbjct 1311 VSSVLQECEKKNYSSICLPAIGTG----NAKQHPDKVAEAI----------IDAIEDFVQ 1356
Query 1373 WNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTT 1430
+ + + L V A + +R+ + Q+ V+ A F ++ ++
Sbjct 1357 KGSAQSVKKVKVVIFLPQVLDVFYANMK--KREGTQLSSQQSVMSKLASFLGFSKQSP 1412
>sp|P0C6F3|R1A_BEV Replicase polyprotein 1a OS=Berne virus OX=11156
GN=1a PE=1 SV=1
Length=4569
Score = 137 bits (346), Expect = 3e-30, Method: Composition-based stats.
Identities = 54/248 (22%), Positives = 97/248 (39%), Gaps = 25/248 (10%)
Query 966 SAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEV 1025
++ + E+ + ++ D ++ T + + + L++
Sbjct 1629 CLTVKVNAKNEKLDIGSQCERVFVDYDVKKNEWTLSPEEGEDSDDNLDLPF--------- 1679
Query 1026 NSFSGYLKLTDNVYIKNADIVEEAKKVK----PTVVVNAANVYLKHGGGVAGALNKATNN 1081
+ + NV + D + +K VVN AN LKHGGG+A ++
Sbjct 1680 EQYYEFKIGQTNVVLVQDDFKSVFEFLKSEQGVDYVVNPANSQLKHGGGIAKVISCMCGP 1739
Query 1082 AMQVESDDYIATNGPLKVGGSCVLSGHNLAKHC--LHVVGPNVNKGEDIQLLKSAYENF- 1138
+Q S++YI N + V + G L K +H VGP V+ G+ Q L A+ +
Sbjct 1740 KLQAWSNNYITKNKTVPVTKAIKSPGFQLGKKVNIIHAVGPRVSDGDVFQKLDQAWRSVF 1799
Query 1139 ---NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKS 1195
+L +LS GIFG S + V A DK+L +V++ +E +
Sbjct 1800 DLCEDQHTILTSMLSTGIFGCTVNDSFNTFLSNV------ARLDKSLVVFVVTNMVEQYN 1853
Query 1196 EKQVEQKI 1203
+ K+
Sbjct 1854 QAFAVIKM 1861
Score = 42.0 bits (97), Expect = 0.30, Method: Composition-based stats.
Identities = 39/246 (16%), Positives = 82/246 (33%), Gaps = 41/246 (17%)
Query 3028 TNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLM 3087
+ +P + + + +++ ++ + + +Y+ + F + + +
Sbjct 3055 FEIISPYV--FVFIVVIFTVIFLILIRLYIVMYSYFKVFTYVVFKLLFVNIIMVLFVVCL 3112
Query 3088 SFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIIC 3147
V + V + + LYL F + + + ++ M V +W+ + +
Sbjct 3113 PPLVPGVVFVLALWLCDSVMFLLYLAFLSLFILPWFYVLFFLFMVGGFVFWWMMRSADVV 3172
Query 3148 ISTKHFYWFFSNYLKRRVVFNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNR 3206
+ +G++F TFE+ + C F LN + + +LL +
Sbjct 3173 ----------------HLTTDGLTFNGTFEQISKCVFPLNP----LIVNRMLLDCQMSHS 3212
Query 3207 YLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGF 3266
L +K K G LA + +G YQP S QS F
Sbjct 3213 DLVEKSKLKTTEGK-------------LANEMMKVFMTGETSYYQPSNFSF-----QSVF 3254
Query 3267 RKMAFP 3272
K P
Sbjct 3255 SKATSP 3260
>sp|Q8IXQ6|PARP9_HUMAN Protein mono-ADP-ribosyltransferase PARP9
OS=Homo sapiens OX=9606 GN=PARP9 PE=1 SV=2
Length=854
Score = 136 bits (342), Expect = 3e-30, Method: Composition-based stats.
Identities = 50/208 (24%), Positives = 79/208 (38%), Gaps = 20/208 (10%)
Query 1012 LEMELTPVVQTIEVNSFSGYLKL-TDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGG 1070
L VQ S + K+ T + + ++ VVNAAN L HGGG
Sbjct 91 CISTLVSPVQEGNSKSLQVFRKMLTPRIELSVWK--DDLTTHAVDAVVNAANEDLLHGGG 148
Query 1071 VAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGED-- 1127
+A AL KA +Q ES ++A G + G V L K +H VGP + +
Sbjct 149 LALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQIIHAVGPRWMEWDKQG 208
Query 1128 -IQLLKSAYENFNQH--------EVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVF 1178
L+ A + + + + P LS+GIF L +C T+ + +++
Sbjct 209 CTGKLQRAIVSILNYVIYKNTHIKTVAIPALSSGIFQFP----LNLCTKTIVETIRVSLQ 264
Query 1179 DKNLYDKLVSSFLEMKSEKQVEQKIAEI 1206
K + L L + +E
Sbjct 265 GKPMMSNLKEIHL-VSNEDPTVAAFKAA 291
Score = 50.5 bits (119), Expect = 7e-04, Method: Composition-based stats.
Identities = 39/221 (18%), Positives = 67/221 (30%), Gaps = 38/221 (17%)
Query 1022 TIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNN 1081
SF+ + + I I + V+VN+ N + G VA ++ +
Sbjct 303 QETTPSFNAMVVNNLTLQIVQGHIEWQ----TADVIVNSVNPHDITVGPVAKSILQQAGV 358
Query 1082 AMQVE-----SDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVV------GPNVNKGEDIQ 1129
M+ E + + + L V G NL K+ HV+ P + K +
Sbjct 359 EMKSEFLATKAKQFQRSQLVL------VTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKE 412
Query 1130 LLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT----------NVYLAVF- 1178
L+ E + P L G + + D V T V +F
Sbjct 413 CLEKCIEQ--NITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFP 470
Query 1179 -DKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITES 1218
D +Y S K K + +P+ +
Sbjct 471 TDLEIYKAFSSEM--AKRSKMLSLNNYSVPQSTREEKRENG 509
>sp|Q9HJ67|Y1105_THEAC Uncharacterized protein Ta1105 OS=Thermoplasma
acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062
/ NBRC 15155 / AMRC-C165) OX=273075 GN=Ta1105 PE=4 SV=2
Length=196
Score = 123 bits (308), Expect = 1e-29, Method: Composition-based stats.
Identities = 39/176 (22%), Positives = 69/176 (39%), Gaps = 24/176 (14%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGP- 1096
+ ++ DI E +VNAAN L GGGV GA++ A + E P
Sbjct 11 LAVEVGDITES----DAEAIVNAANSSLMGGGGVDGAIHSAAGPELNGELVKIRRERYPN 66
Query 1097 -LKVGGSCVLSGHNL-AKHCLHVVGPNVNKGE--DIQLLKSAYEN----FNQHEV--LLA 1146
L G + + G+ L A H +H VGP G + +L +Y + + + +
Sbjct 67 GLPPGEAVITRGYRLKASHIIHTVGPVWMGGRNGEDDVLYRSYRSCLDLAREFGIHDIAF 126
Query 1147 PLLSAGIFGADPIHSLRVCVDTVRT---------NVYLAVFDKNLYDKLVSSFLEM 1193
P LS G +G + R+ + +V V + ++ + + ++
Sbjct 127 PALSTGAYGFPFDRAERIAIRSVIDFLKDESAGYTVRFVFYTEDQGKRFLFILSDL 182
>sp|Q5ZKG3|DNA2_CHICK DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Gallus gallus OX=9031 GN=DNA2 PE=2 SV=2
Length=992
Score = 134 bits (338), Expect = 1e-29, Method: Composition-based stats.
Identities = 72/369 (20%), Positives = 125/369 (34%), Gaps = 82/369 (22%)
Query 5594 QKVGMQKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLP- 5650
Q + + Y+ + G PGTGK+ A+ L ++ T+ +H AVD + K K+
Sbjct 605 QVLLSRDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSFTHTAVDNILLKLAKFKVG 664
Query 5651 ----------IDKCSRIIPARA----RVECFDKFKV--NSTLEQYVFCT---VNALPETT 5691
+ ++ + NS C +
Sbjct 665 FLRLGRAQKVHPDIRKFTEEEICRSKSIKSVTDLEELYNSQPVVATACMGINHPIFVQKQ 724
Query 5692 ADIVVFDEISMATNYDLSVVNARLRA-KHYVYIGDPAQLPA--PRTLLTKGTLEPEYFNS 5748
D + DE S + + L K +V +GD QLP + + F
Sbjct 725 FDFCIVDEASQISQ---PICLGPLFCSKRFVLVGDHQQLPPLVQNSEARDLGMSESLFK- 780
Query 5749 VCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDV 5808
RL + + L R ++I+ + LVY+ KL+ +K
Sbjct 781 --RLEQNQNAVVQLTVQYRMNSKIMSLSNKLVYEGKLECGSEK---------------VS 823
Query 5809 SSAINRPQIGVVR-EFLTRNPAWRKAVF-----------------------ISPYNSQNA 5844
++ N P + +++ EF + W K V ISPY Q
Sbjct 824 NATANLPNLKMLKLEFADASKTWLKEVLEPDKPVCFLNTEKAGCRPSDIGIISPYRHQLK 883
Query 5845 VASKILG------LPTQTVDSSQGSEYDYVIFTQTTET------AHSCNVNRFNVAITRA 5892
V + ++ + T+D QG + +I + + A + R NVAITRA
Sbjct 884 VITDLMARLKENRVEVNTIDKYQGRDKSIIIVSFVRNSNDENLGALLKDWRRLNVAITRA 943
Query 5893 KVGILCIMS 5901
K ++ +
Sbjct 944 KHKLIMVGC 952
>sp|Q00416|SEN1_YEAST Helicase SEN1 OS=Saccharomyces cerevisiae
(strain ATCC 204508 / S288c) OX=559292 GN=SEN1 PE=1 SV=2
Length=2231
Score = 132 bits (332), Expect = 1e-28, Method: Composition-based stats.
Identities = 62/310 (20%), Positives = 100/310 (32%), Gaps = 43/310 (14%)
Query 5690 TTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV 5749
D V+ DE T S++ R K + +GDP QLP T+L+ +Y S+
Sbjct 1582 IKFDTVIIDEACQCTELS-SIIPLRYGGKRCIMVGDPNQLPP--TVLSGAASNFKYNQSL 1638
Query 5750 CRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAH--------------KDKSAQC 5795
M+ L R I S+ Y +LK + +
Sbjct 1639 FVRMEKNSSPYLLDVQYRMHPSISKFPSSEFYQGRLKDGPGMDILNKRPWHQLEPLAPYK 1698
Query 5796 FKMFYKGVITHD--VSSAINRPQI--------GVVREFLTRNPAWRKAVFISPYNSQNAV 5845
F G + S N +I + R+F + K ISPY Q
Sbjct 1699 FFDIISGRQEQNAKTMSYTNMEEIRVAIELVDYLFRKFDNKIDFTGKIGIISPYREQMQK 1758
Query 5846 ASKIL----------GLPTQTVDSSQGSEYDYVIFT------QTTETAHSCNVNRFNVAI 5889
K + T+D QG E + ++ + + + R NVA+
Sbjct 1759 MRKEFARYFGGMINKSIDFNTIDGFQGQEKEIILISCVRADDTKSSVGFLKDFRRMNVAL 1818
Query 5890 TRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAP 5949
TRAK I + R L + L ++ + L L ++ + L P
Sbjct 1819 TRAKTSIWVLGHQRSLAKSKLWRDLIEDAKDRSCLAYACSGFLDPRNNRAQSILRKFNVP 1878
Query 5950 THLSVDTKFK 5959
+ +K
Sbjct 1879 VPSEQEDDYK 1888
Score = 42.0 bits (97), Expect = 0.27, Method: Composition-based stats.
Identities = 26/104 (25%), Positives = 41/104 (39%), Gaps = 27/104 (26%)
Query 5596 VGMQKYSTLQGPPGTGKSHFAIGLALYYPS---------------------------ARI 5628
V + +S +QGPPGTGK+ +G+ Y+ S +I
Sbjct 1347 VSKEGFSLIQGPPGTGKTKTILGIIGYFLSTKNASSSNVIKVPLEKNSSNTEQLLKKQKI 1406
Query 5629 VYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKV 5672
+ A S+AAVD +C + + + + P RV D V
Sbjct 1407 LICAPSNAAVDEICLRLKSGVYDKQGHQFKPQLVRVGRSDVVNV 1450
>sp|Q86AS0|Y4399_DICDI Probable helicase DDB_G0274399 OS=Dictyostelium
discoideum OX=44689 GN=DDB_G0274399 PE=3 SV=1
Length=967
Score = 130 bits (326), Expect = 4e-28, Method: Composition-based stats.
Identities = 57/265 (22%), Positives = 101/265 (38%), Gaps = 35/265 (13%)
Query 5692 ADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCR 5751
DIV+ DE + A +++ + K V +GDP QLPA T+++ ++ +Y S+ +
Sbjct 585 FDIVIIDEAAQAVETS-TLIPIQHGCKKVVLVGDPKQLPA--TIISPLAIKYKYDQSLFQ 641
Query 5752 LMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQC--------------FK 5797
++ L T R + I S Y + L + ++ +
Sbjct 642 RLQEKNSPHMLTTQYRMHSLIRAFPSRHFYQDLLLDGPNIPSRATHYHSNPFFGPLVFYD 701
Query 5798 MFYKGVITHDVSSAINRPQ----IGVVREFLTRNPAWRKAV---FISPYNSQNAVASKIL 5850
+ + S N + + + + F P A ISPY Q +I
Sbjct 702 LSWSTETKPGGGSVFNEHECKMAMYLFQLFTKVYPDEDFASRIGIISPYRQQVLALREIF 761
Query 5851 ----GLPTQTVDSSQGSEYDYVIFT-------QTTETAHSCNVNRFNVAITRAKVGILCI 5899
G+ TVD QG E + +IF+ + +V R NVA+TR + +L +
Sbjct 762 KNYPGISIDTVDGFQGREREIIIFSCVRAPVEEGAGIGFLSDVRRMNVALTRPRSSLLIL 821
Query 5900 MSDRDLYDKLQFTSLEIPRRNVATL 5924
+ + L + L +N L
Sbjct 822 GNTKALSINKDWNELIQHTQNNQQL 846
>sp|E1BMP7|DNA2_BOVIN DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Bos taurus OX=9913 GN=DNA2 PE=3 SV=3
Length=1061
Score = 128 bits (321), Expect = 2e-27, Method: Composition-based stats.
Identities = 75/384 (20%), Positives = 122/384 (32%), Gaps = 88/384 (23%)
Query 5599 QKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKALKYL------- 5649
+ Y+ + G PGTGK+ + LY ++ T+ +H+AVD + K K+
Sbjct 641 KDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLG 700
Query 5650 ----PIDKCSRIIPARA-RVECFDKFKV-----NSTLEQYVFCT---VNALPETTADIVV 5696
+ R + + NS L C T D +
Sbjct 701 QIQKVHPDIQKFTEEEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKTFDFCI 760
Query 5697 FDEISMATNYDLSVVNARLRA-KHYVYIGDPAQLPAPRTLLTKG---TLEPEYFNSVCRL 5752
DE S + V L + +V +GD QLP P L + + F RL
Sbjct 761 VDEASQISQ---PVCLGPLFFSRRFVLVGDHQQLP-PLVLNREARALGMSESLFK---RL 813
Query 5753 MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLK-------------------------- 5786
+ + L R ++I+ + L Y+ KL+
Sbjct 814 EQNKNAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLPNFKDVKLELEFY 873
Query 5787 -----------AHKDKSAQCFKMFYK--GVITHDVSSAINRPQIGVVR----EFLTRNPA 5829
A + + CF +K + N + +V F+
Sbjct 874 ADYSENPWLIAAFEPNNPVCFLNTHKVPAPEQVEKGGVSNIMEAKLVVFLTSVFIKAGCK 933
Query 5830 WRKAVFISPYNSQNAVASKILG------LPTQTVDSSQGSEYDYVIFTQTTETAHSC--- 5880
I+PY Q V S +L + TVD QG + V+ +
Sbjct 934 PSDIGIIAPYRQQLKVISDLLAQSSVGMVEVNTVDRYQGRDKSIVVVSFVRSNEDGTLGE 993
Query 5881 ---NVNRFNVAITRAKVGILCIMS 5901
+ R NVAITRAK ++ +
Sbjct 994 LLKDWRRLNVAITRAKHKLILLGC 1017
>sp|P0C6F4|R1A_BRV1 Replicase polyprotein 1a OS=Breda virus 1
OX=360393 GN=1a PE=3 SV=1
Length=4445
Score = 127 bits (318), Expect = 6e-27, Method: Composition-based stats.
Identities = 52/252 (21%), Positives = 89/252 (35%), Gaps = 18/252 (7%)
Query 929 EDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSA-ALQPEEEQEEDWLDDDSQQT 987
+E + + +E T + L + L + + E + LD S
Sbjct 1543 CEEFDSAYTLQTISDEVSFETSTSPELVACVLAYAIGYELCLTVKTDGECESLDVGSSLE 1602
Query 988 VGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVE 1047
D + T ++ ++EL N + + +V + D
Sbjct 1603 QVYVDYDVSKNVWDLSTHLQDDSSDDLELP-------FNQYYEFKVGRASVVLVQDDFKS 1655
Query 1048 EAKKVK----PTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSC 1103
+K VVN AN LKHGGG+A ++ + S++YI L V +
Sbjct 1656 VYDFLKSEQGVDYVVNPANNQLKHGGGIAKVISCMCGPKLTSWSNNYIKQYKKLGVTCAI 1715
Query 1104 VLSGHNLAK--HCLHVVGPNVNKGEDIQLLKS----AYENFNQHEVLLAPLLSAGIFGAD 1157
G L K +HVVGP + + L++ ++N +L +LS GIFG
Sbjct 1716 RSPGFQLGKGVQIIHVVGPKSADSDVVNKLEASWRSVFQNVKPDTTVLTSMLSTGIFGCS 1775
Query 1158 PIHSLRVCVDTV 1169
S + +
Sbjct 1776 VTDSATTLLSNL 1787
Score = 54.3 bits (129), Expect = 7e-05, Method: Composition-based stats.
Identities = 52/227 (23%), Positives = 94/227 (41%), Gaps = 31/227 (14%)
Query 3047 IVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYS 3106
+V I IV L ++ F +++VV LLF+ + VL + + +PGV
Sbjct 2944 VVLVAIFTIVFLFLLRMYIVMYSYFKVFTYVVFK--LLFVNTVMVLFVVCLPPLVPGVV- 3000
Query 3107 VIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVV 3166
L +L + V FL ++ + +F ++P++ + +++ + F+W + +
Sbjct 3001 ---FVLALWLCDSVVFLLYLAVLSLF--ILPWFYVMLFVLIVGGFVFWWMMKSSDVVHLT 3055
Query 3167 FNGVSF-STFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTS 3225
+G++F TFE+ + C F LN + + +LL + L +K K G
Sbjct 3056 PDGLTFNGTFEQVSKCVFPLNP----LIVNRLLLDCRMSHSDLVEKSKLKTTEGK----- 3106
Query 3226 YREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFP 3272
LA + +G YQP S QS F K+ P
Sbjct 3107 --------LATEMMKVFMTGETAYYQPSNFSF-----QSVFSKVVSP 3140
>sp|P36328|POLN_EEVVP Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain P676) OX=36385 PE=1 SV=2
Length=2493
Score = 124 bits (312), Expect = 3e-26, Method: Composition-based stats.
Identities = 58/230 (25%), Positives = 93/230 (40%), Gaps = 33/230 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ ++ DI + V++NAAN + GGGV GAL K + ++
Sbjct 1329 CAPSYHVVRGDIATATEG----VIINAANSKGQPGGGVCGALYKKFPESFDLQ------- 1377
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVL 1144
P++VG + ++ G AKH +H VGPN NK +++ L AYE N N ++ +
Sbjct 1378 --PIEVGKARLVKG--AAKHIIHAVGPNFNKVSEVEGDKQLAEAYESIAKIVNDNNYKSV 1433
Query 1145 LAPLLSAGIFGADPIH------SLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS GIF + L +DT +V + DK L + + +
Sbjct 1434 AIPLLSTGIFSGNKDRLTQSLNHLLTALDTTDADVAIYCRDKKWEMTLKEA---VARREA 1490
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKF 1248
VE+ +P + + K + + LE TKF
Sbjct 1491 VEEICISDDSSVTEPDAELVRVHPKSSLAGRKGYSTSDGKTFSYLEGTKF 1540
Score = 54.3 bits (129), Expect = 6e-05, Method: Composition-based stats.
Identities = 61/297 (21%), Positives = 93/297 (31%), Gaps = 62/297 (21%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS G+ + + L A K + C+ II
Sbjct 719 VYGVPGSGKS----GIIKSAVTKK------------DLVVSAKK----ENCAEIIRD--- 755
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5723
V+ VN+ V +N + + + DE L + A +R K V
Sbjct 756 VKKMKGLDVNARTVDSVL--LNG-CKHPVETLYIDEAFACHAGTLRALIAIIRPKKAVLC 812
Query 5724 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5783
GDP Q + K E V RRC + VS L YD
Sbjct 813 GDPKQCGFFNMMCLKVHFNHEICTQVFHK----------SISRRCTKSVTSVVSTLFYDK 862
Query 5784 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5843
+++ K I D + + Q ++ LT W K + I Y
Sbjct 863 RMRTTNPKET---------KIVIDTTGSTKPKQDDLI---LTCFRGWVKQLQID-YK--- 906
Query 5844 AVASKILGLPTQTVDSSQGSEYDYVI---FTQTTETAHSCNVNRFNVAITRAKVGIL 5897
G T +SQG V + ++ NV +TR + I+
Sbjct 907 -------GNEIMTAAASQGLTRKGVYAVRYKVNENPLYAPTSEHVNVLLTRTEDRIV 956
>sp|P36327|POLN_EEVV3 Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain 3880) OX=36382 PE=3 SV=3
Length=2485
Score = 124 bits (311), Expect = 3e-26, Method: Composition-based stats.
Identities = 59/230 (26%), Positives = 93/230 (40%), Gaps = 33/230 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ ++ DI + V++NAAN + GGGV GAL K + ++
Sbjct 1329 CAPSYHVVRGDIATATEG----VIINAANSKGQPGGGVCGALYKKFPESFDLQ------- 1377
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVL 1144
P++VG + ++ G AKH +H VGPN NK +I+ L AYE N N ++ +
Sbjct 1378 --PIEVGKARLVKG--AAKHIIHAVGPNFNKVSEIEGDKQLAEAYESIAKIVNDNNYKSV 1433
Query 1145 LAPLLSAGIFGADPIH------SLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS GIF + L +DT +V + DK L + + +
Sbjct 1434 AIPLLSTGIFSGNKDRLTQSLNHLLTALDTTDADVAIYCRDKKWEMTLKEA---VARREA 1490
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKF 1248
VE+ +P + + K + + LE TKF
Sbjct 1491 VEEICISDDSSVTEPDAELVRVHPKSSLAGRKGYSTSDGKTFSYLEGTKF 1540
Score = 53.2 bits (126), Expect = 1e-04, Method: Composition-based stats.
Identities = 55/297 (19%), Positives = 90/297 (30%), Gaps = 62/297 (21%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS G+ + + + + + + +D +R + +
Sbjct 719 VYGVPGSGKS----GIIKSAVTKKDLVVSAKKENCAEIIRDVKRIKGLDVNARTVDSVLL 774
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5723
C K+ V + + DE L + A +R K V
Sbjct 775 NGC--KYPV--------------------ETLYIDEAFACHAGTLRALIAIIRPKKAVLC 812
Query 5724 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5783
GDP Q + K E V RRC + VS L YD
Sbjct 813 GDPKQCGFFNMMCLKVHFNHEICTQVFHK----------SISRRCTKSVTSVVSTLFYDK 862
Query 5784 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5843
+++ K I D + + Q ++ LT W K + I Y
Sbjct 863 RMRTTNPKET---------KIEIDTTGSTKPKQDDLI---LTCFRGWVKQLQID-YK--- 906
Query 5844 AVASKILGLPTQTVDSSQGSEYDYVI---FTQTTETAHSCNVNRFNVAITRAKVGIL 5897
G T +SQG V + ++ NV +TR + I+
Sbjct 907 -------GNEVMTAAASQGLTRKGVYAVRYKVNENPLYAPTSEHVNVLLTRTEDRIV 956
>sp|P27282|POLN_EEVVT Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain Trinidad donkey) OX=11038 PE=1 SV=3
Length=2493
Score = 124 bits (311), Expect = 3e-26, Method: Composition-based stats.
Identities = 58/230 (25%), Positives = 93/230 (40%), Gaps = 33/230 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ ++ DI + V++NAAN + GGGV GAL K + ++
Sbjct 1329 CAPSYHVVRGDIATATEG----VIINAANSKGQPGGGVCGALYKKFPESFDLQ------- 1377
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVL 1144
P++VG + ++ G AKH +H VGPN NK +++ L AYE N N ++ +
Sbjct 1378 --PIEVGKARLVKG--AAKHIIHAVGPNFNKVSEVEGDKQLAEAYESIAKIVNDNNYKSV 1433
Query 1145 LAPLLSAGIFGADPIH------SLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS GIF + L +DT +V + DK L + + +
Sbjct 1434 AIPLLSTGIFSGNKDRLTQSLNHLLTALDTTDADVAIYCRDKKWEMTLKEA---VARREA 1490
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKF 1248
VE+ +P + + K + + LE TKF
Sbjct 1491 VEEICISDDSSVTEPDAELVRVHPKSSLAGRKGYSTSDGKTFSYLEGTKF 1540
Score = 54.7 bits (130), Expect = 4e-05, Method: Composition-based stats.
Identities = 62/297 (21%), Positives = 93/297 (31%), Gaps = 62/297 (21%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS G+ + + L A K + C+ II
Sbjct 719 VYGVPGSGKS----GIIKSAVTKK------------DLVVSAKK----ENCAEIIRD--- 755
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5723
V+ VN+ V +N + + + DE L + A +R K V
Sbjct 756 VKKMKGLDVNARTVDSVL--LNG-CKHPVETLYIDEAFACHAGTLRALIAIIRPKKAVLC 812
Query 5724 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5783
GDP Q + K E V RRC + VS L YD
Sbjct 813 GDPKQCGFFNMMCLKVHFNHEICTQVFHK----------SISRRCTKSVTSVVSTLFYDK 862
Query 5784 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5843
K++ K I D + + Q ++ LT W K + I Y
Sbjct 863 KMRTTNPKET---------KIVIDTTGSTKPKQDDLI---LTCFRGWVKQLQID-YK--- 906
Query 5844 AVASKILGLPTQTVDSSQGSEYDYVI---FTQTTETAHSCNVNRFNVAITRAKVGIL 5897
G T +SQG V + ++ NV +TR + I+
Sbjct 907 -------GNEIMTAAASQGLTRKGVYAVRYKVNENPLYAPTSEHVNVLLTRTEDRIV 956
>sp|P51530|DNA2_HUMAN DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Homo sapiens OX=9606 GN=DNA2 PE=1 SV=3
Length=1060
Score = 123 bits (309), Expect = 3e-26, Method: Composition-based stats.
Identities = 71/383 (19%), Positives = 121/383 (32%), Gaps = 87/383 (23%)
Query 5599 QKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKALKYL------- 5649
+ Y+ + G PGTGK+ + LY ++ T+ +H+AVD + K K+
Sbjct 641 KDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLG 700
Query 5650 ----PIDKCSRIIPARA-RVECFDKFKV-----NSTLEQYVFCT---VNALPETTADIVV 5696
+ R + + NS L C D +
Sbjct 701 QIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCI 760
Query 5697 FDEISMATNYDLSVVNARLRA-KHYVYIGDPAQLPAPRTLLTKG---TLEPEYFNSVCRL 5752
DE S + + L + +V +GD QLP P L + + F RL
Sbjct 761 VDEASQISQ---PICLGPLFFSRRFVLVGDHQQLP-PLVLNREARALGMSESLFK---RL 813
Query 5753 MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDK------SAQCFKMF------- 5799
+ + L R ++I+ + L Y+ KL+ DK + + FK
Sbjct 814 EQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFY 873
Query 5800 --------------------------YKGVITHDVSSAINRPQIGVVR----EFLTRNPA 5829
+ N + ++ F+ +
Sbjct 874 ADYSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCS 933
Query 5830 WRKAVFISPYNSQ-----NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC---- 5880
I+PY Q + +A I + TVD QG + V+ +
Sbjct 934 PSDIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGEL 993
Query 5881 --NVNRFNVAITRAKVGILCIMS 5901
+ R NVAITRAK ++ +
Sbjct 994 LKDWRRLNVAITRAKHKLILLGC 1016
>sp|Q9HEH1|RENT1_NEUCR Regulator of nonsense transcripts 1 homolog
OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A /
CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=2E4.130 PE=3
SV=1
Length=1093
Score = 123 bits (309), Expect = 4e-26, Method: Composition-based stats.
Identities = 92/455 (20%), Positives = 158/455 (35%), Gaps = 109/455 (24%)
Query 5546 GDYF-VLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTL 5604
G F L H V APT + + GL + +S +A ++V S +
Sbjct 424 GYIFHKLLGHEVQ--VAPTKITMPKKFHVPGL------PELNASQIAAIKQVLSNPLSLI 475
Query 5605 QGPPGTGKS----HFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPA 5660
QGPPGTGK+ LA +++++ A S+ AVD LCE+ + + +
Sbjct 476 QGPPGTGKTVTSATIIYHLAKMS-NSQVLVCAPSNVAVDQLCERIHRT-GLKVVRLTAKS 533
Query 5661 RARVECFDKF-------KVNSTLEQ----------------------------------- 5678
R VE F ++N+T ++
Sbjct 534 REDVESSVSFLALHEQVRMNTTNKELDGLVKLKTETGELSSQDEKRFKQLTRQAEREILQ 593
Query 5679 ---YVFCT-VNA----LPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLP 5730
V CT V A L + V+ DE + + + ++ L K V +GD QL
Sbjct 594 NADVVCCTCVGAGDPRLSKMKFRNVLIDESTQSAEPEC-MIPLVLGCKQVVLVGDHKQLG 652
Query 5731 APRTLLTKGTLEPEYFNSVC-RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHK 5789
++ K + S+ RL+K + L R + + S + Y+ L+
Sbjct 653 P--VIMNKKAAKAGLNQSLFERLVKLQFTPIRLKVQYRMHPCLSEFPSNMFYEGSLQNGV 710
Query 5790 ----------------DKSAQCFKMFYKGVITHDVSSAI-NRPQIGVVREFLTRN----- 5827
++ F ++ NR + V + +TR
Sbjct 711 TAAERLRKDVDFPWPVPETPMMFWSNLGNEEISASGTSYLNRTEAANVEKIVTRFFKAGV 770
Query 5828 PAWRKAVFISPYNSQNAV------------ASKILGLPTQTVDSSQGSEYDYVIFT---- 5871
V I+PY Q + + +VD+ QG E D+++ +
Sbjct 771 KPADIGV-ITPYEGQRSYIVNTMQNTGTFKKESYREVEVASVDAFQGREKDFIVLSCVRS 829
Query 5872 -QTTETAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
+ + R NVA+TRAK G++ I + + L
Sbjct 830 NENQGIGFLSDPRRLNVALTRAKYGLVIIGNPKVL 864
>sp|D3ZG52|DNA2_RAT DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Rattus norvegicus OX=10116 GN=Dna2 PE=3 SV=1
Length=1059
Score = 123 bits (308), Expect = 5e-26, Method: Composition-based stats.
Identities = 79/431 (18%), Positives = 140/431 (32%), Gaps = 102/431 (24%)
Query 5599 QKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKALK--------- 5647
+ Y+ + G PGTGK+ A+ L ++ T+ +H+AVD + K K
Sbjct 641 KDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLG 700
Query 5648 --YLPIDKCSRIIPA---RARV--------ECFDKFKVNSTLEQYVFCTVNALPETTADI 5694
+ + R R E ++ V +T + + T D
Sbjct 701 QSHKVHPDIQKFTEEEMCRLRSIASLAHLEELYNSHPVVATTCMGI--SHPMFSRKTFDF 758
Query 5695 VVFDEISMATNYDLSVVNARLRA-KHYVYIGDPAQLPAPRTLLTKG---TLEPEYFNSVC 5750
+ DE S + + L + +V +GD QLP P L + + F
Sbjct 759 CIVDEASQISQ---PICLGPLFFSRRFVLVGDHKQLP-PLVLNREARALGMSESLFK--- 811
Query 5751 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD-------------------- 5790
RL + + L R +I+ + L Y+ KL+ D
Sbjct 812 RLERNESAVVQLTIQYRMNRKIMSLSNKLTYEGKLECGSDRVANAVITLPNLKDVRLEFY 871
Query 5791 ---------------KSAQCF--KMFYKGVITHDVSSAINRPQIGVVR----EFLTRNPA 5829
+ CF + N + ++ F+ +
Sbjct 872 ADYSDNPWLAGVFEPDNPVCFLNTDKVPAPEQIENGGVSNVTEARLIVFLTSTFIKAGCS 931
Query 5830 WRKAVFISPYNSQ-----NAVASKILGL-PTQTVDSSQGSEYDYVIFTQTTETAHSC--- 5880
I+PY Q + +A +G+ TVD QG + ++ +
Sbjct 932 PSDIGIIAPYRQQLRTITDLLARSSVGMVEVNTVDKYQGRDKSLILVSFVRSNEDGTLGE 991
Query 5881 ---NVNRFNVAITRAKVGILCIMSDRD---------LYDKLQFTSLEIPRRNVATLQAEN 5928
+ R NVAITRAK ++ + S L+D L L N+ + + E+
Sbjct 992 LLKDWRRLNVAITRAKHKLILLGSVSSLKRFPPLEKLFDHLNAEQL---ISNLPSREHES 1048
Query 5929 VTGLFKDCSKV 5939
+ + DC +
Sbjct 1049 LYHILGDCQRD 1059
>sp|Q9V0Y3|Y656_PYRAB Uncharacterized protein PYRAB06560 OS=Pyrococcus
abyssi (strain GE5 / Orsay) OX=272844 GN=PYRAB06560
PE=4 SV=2
Length=183
Score = 111 bits (278), Expect = 7e-26, Method: Composition-based stats.
Identities = 44/181 (24%), Positives = 73/181 (40%), Gaps = 32/181 (18%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVE----SDDYIAT 1093
+ + DI + K +VNAAN YL+HGGGVA A+ KA + + ++
Sbjct 2 FRVVHGDIT----RFKAEAIVNAANKYLEHGGGVAYAIAKAASGDVSEYIRISKEEMRKQ 57
Query 1094 NGP--LKVGGSCVLSGHNLA----KHCLHVVGPNVN---KGEDIQLLKSAYENFNQH--- 1141
G ++ G V NLA K+ +H VGP + + L+ A +
Sbjct 58 IGRDWIEHGEVVVTPPLNLAKNGVKYVIHTVGPYCGGKWDEDKRKKLELAILGALKKADE 117
Query 1142 ---EVLLAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKNLYDKLVSS 1189
+ P +SAGI+G ++ V T+VYL ++ + Y+ +
Sbjct 118 LGVRSIAFPAISAGIYGCPLEEVVKTFKLVVNEFLKSAKNVTDVYLVLYSERDYEVALKV 177
Query 1190 F 1190
Sbjct 178 L 178
>sp|Q9VYS3|RENT1_DROME Regulator of nonsense transcripts 1 homolog
OS=Drosophila melanogaster OX=7227 GN=Upf1 PE=1 SV=2
Length=1180
Score = 122 bits (306), Expect = 1e-25, Method: Composition-based stats.
Identities = 81/422 (19%), Positives = 137/422 (32%), Gaps = 95/422 (23%)
Query 5575 GLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS----HFAIGLALYYPSARIVY 5630
L+ ++ D S V + + S +QGPPGTGK+ L + ++
Sbjct 442 KLFSAPHLPDLNRSQVYAVKHALQRPLSLIQGPPGTGKTVTSATIVYQLVKLH-GGTVLV 500
Query 5631 TACSHAAVDALCEKALKY--LPIDKCSR------------IIPARARV------------ 5664
A S+ AVD L EK + + C++ + + R
Sbjct 501 CAPSNTAVDQLTEKIHRTNLKVVRVCAKSREAIDSPVSFLALHNQIRNMETNSELKKLQQ 560
Query 5665 -------------ECFDKFKVNSTL-----EQYVFCTV-----NALPETTADIVVFDEIS 5701
+ + K + + CT L ++ DE
Sbjct 561 LKDETGELSSADEKRYRNLKRAAENQLLEAADVICCTCVGAGDGRLSRVKFTSILIDESM 620
Query 5702 MATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMF 5761
+T + +V L AK + +GD QL ++ K S+ + +G F
Sbjct 621 QSTEPEC-MVPVVLGAKQLILVGDHCQLGP--VVMCKKAARAGLSQSLFERLVVLGIRPF 677
Query 5762 -LGTCRRCPAEIVDTVSALVYDNKLK--------------AHKDKSAQCFKMFYKGVITH 5806
L R E+ S Y+ L+ F + +G
Sbjct 678 RLEVQYRMHPELSQFPSNFFYEGSLQNGVCAEDRRLKLDFPWPQPERPMFFLVTQGQEEI 737
Query 5807 DVS--SAINRPQIGVVR----EFLTRNPAWRKAVFISPYNSQNAVASKIL---------- 5850
S S +NR + V FL + I+PY Q A + +
Sbjct 738 AGSGTSFLNRTEAANVEKITTRFLKAGIKPEQIGIITPYEGQRAYLVQYMQYQGSLHSRL 797
Query 5851 --GLPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAITRAKVGILCIMSDR 5903
+ +VD+ QG E D +I + + + R NVA+TRAK GI+ + + +
Sbjct 798 YQEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRAKFGIIIVGNPK 857
Query 5904 DL 5905
L
Sbjct 858 VL 859
>sp|Q6ZQJ5|DNA2_MOUSE DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Mus musculus OX=10090 GN=Dna2 PE=1 SV=2
Length=1062
Score = 121 bits (304), Expect = 2e-25, Method: Composition-based stats.
Identities = 72/432 (17%), Positives = 134/432 (31%), Gaps = 102/432 (24%)
Query 5599 QKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKALK--------- 5647
+ Y+ + G PGTGK+ A+ L ++ T+ +H+AVD + K K
Sbjct 642 KDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSYTHSAVDNILLKLAKFKVGFLRLG 701
Query 5648 --YLPIDKCSRIIPARARVEC-----------FDKFKVNSTLEQYVFCTVNALPETTADI 5694
+ + ++ + +T + T D
Sbjct 702 QSHKVHPDIQKFTEEEICRSRSIASLAHLEELYNSHPIVATTCMGI--NHPIFSRKTFDF 759
Query 5695 VVFDEISMATNYDLSVVNARLRA-KHYVYIGDPAQLPAPRT--LLTKGTLEPEYFNSVCR 5751
+ DE S + V L + +V +GD QLP + F R
Sbjct 760 CIVDEASQISQ---PVCLGPLFFSRRFVLVGDHQQLPPLVVNREARALGMSESLFK---R 813
Query 5752 LMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDK----------------SAQC 5795
L + + L R +I+ + L Y KL+ D+ S Q
Sbjct 814 LERNESAVVQLTVQYRMNRKIMSLSNKLTYAGKLECGSDRVANAVLALPNLKDARLSLQL 873
Query 5796 FKMF-----------------------YKGVITHDVSSAINRPQIGVVR----EFLTRNP 5828
+ + + N + ++ F+
Sbjct 874 YADYSDSPWLAGVLEPDNPVCFLNTDKVPAPEQVENGGVSNVTEARLIVFLTSTFIKAGC 933
Query 5829 AWRKAVFISPYNSQNAVASKILG------LPTQTVDSSQGSEYDYVIFTQTTETAHSC-- 5880
+ I+PY Q + S +L + TVD QG + ++ +
Sbjct 934 SPSDIGVIAPYRQQLRIISDLLARSSVGMVEVNTVDKYQGRDKSLILVSFVRSNEDGTLG 993
Query 5881 ----NVNRFNVAITRAKVGILCIMSDR---------DLYDKLQFTSLEIPRRNVATLQAE 5927
+ R NVA+TRAK ++ + S L+D L L + + + + E
Sbjct 994 ELLKDWRRLNVALTRAKHKLILLGSVSSLKRFPPLGTLFDHLNAEQLILD---LPSREHE 1050
Query 5928 NVTGLFKDCSKV 5939
+++ + DC +
Sbjct 1051 SLSHILGDCQRD 1062
>sp|Q9WJC7|POLN_EEVVM Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain Mena II) OX=36384 PE=3 SV=3
Length=2499
Score = 122 bits (305), Expect = 2e-25, Method: Composition-based stats.
Identities = 55/230 (24%), Positives = 90/230 (39%), Gaps = 33/230 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ ++ DI + V+VNAAN + G GV GAL + + ++
Sbjct 1329 CAPSYHVVRGDIATATEG----VIVNAANSKGQPGSGVCGALYRKYPESFDLQ------- 1377
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVL 1144
P++VG + ++ G +KH +H VGPN +K +++ L AYE N N + +
Sbjct 1378 --PIEVGKARLVKGS--SKHIIHAVGPNFSKVSEVEGDKQLAEAYESIAKIINDNNYRSV 1433
Query 1145 LAPLLSAGIFGADPIH------SLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS GIF + L +DT +V + DK L + +
Sbjct 1434 AIPLLSTGIFAGNKDRLMQSLNHLLTALDTTDADVAIYCRDKKWEVTLKEV---VARREA 1490
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKF 1248
VE+ +P + + K + + LE TKF
Sbjct 1491 VEEICISEDSSVAEPDAELVRVHPKSSLAGRKGYSTSDGKTFSYLEGTKF 1540
Score = 53.9 bits (128), Expect = 8e-05, Method: Composition-based stats.
Identities = 59/297 (20%), Positives = 94/297 (32%), Gaps = 62/297 (21%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS G+ + + L A K + C+ II
Sbjct 719 VYGVPGSGKS----GIIKSAVTKK------------DLVVSAKK----ENCAEIIRD--- 755
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5723
V+ VN+ V +N + + + DE L + A +R K V
Sbjct 756 VKKMKGLDVNARTVDSVL--LNG-CKHPVETLYIDEAFACHAGTLRALIAIIRPKKAVLC 812
Query 5724 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5783
GDP Q + K E V RRC + VS L YD
Sbjct 813 GDPKQCGFFNMMCLKVHFNHEICTQVFHK----------SISRRCTKSVTSVVSTLFYDK 862
Query 5784 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5843
+++ + + I D + + + ++ LT W K + I Y
Sbjct 863 RMRTTNPRDS---------KIEIDTTGSTKSKKEDLI---LTCFRGWVKQLQID-YK--- 906
Query 5844 AVASKILGLPTQTVDSSQGSEYDYVI---FTQTTETAHSCNVNRFNVAITRAKVGIL 5897
G T +SQG V + ++ NV +TR + I+
Sbjct 907 -------GNEIMTAAASQGLTRKSVYAVRYKVNENPLYAPTSEHVNVLLTRTEDKIV 956
>sp|Q8V294|POLN_EEVVC Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain CPA201) OX=376610 PE=3 SV=3
Length=2497
Score = 122 bits (305), Expect = 2e-25, Method: Composition-based stats.
Identities = 56/230 (24%), Positives = 91/230 (40%), Gaps = 33/230 (14%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ ++ DI + V+VNAAN + G GV GAL + + ++
Sbjct 1329 CAPSYHVVRGDIATATEG----VIVNAANSKGQPGSGVCGALYRKYPESFDLQ------- 1377
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVL 1144
P++VG + ++ G+ +KH +H VGPN NK +++ L AYE N N + +
Sbjct 1378 --PIEVGKARLVKGN--SKHLIHAVGPNFNKVSEVEGDKQLAEAYESIARIINDNNYRSV 1433
Query 1145 LAPLLSAGIFGADPIH------SLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS GIF + L +DT +V + DK L + +
Sbjct 1434 AIPLLSTGIFAGNKDRLMQSLNHLLTALDTTDADVAIYCRDKKWEVTLKEV---VARREA 1490
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKF 1248
VE+ +P + + K + + LE TKF
Sbjct 1491 VEEICISEDSSVAEPDAELVRVHPKSSLAGRKGYSTSDGKTFSYLEGTKF 1540
Score = 52.4 bits (124), Expect = 2e-04, Method: Composition-based stats.
Identities = 59/297 (20%), Positives = 94/297 (32%), Gaps = 62/297 (21%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS G+ + + L A K + C+ II
Sbjct 719 VYGVPGSGKS----GIIKSAVTKK------------DLVVSAKK----ENCAEIIRD--- 755
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5723
V+ VN+ V +N + + + DE L + A +R K V
Sbjct 756 VKKMKGLDVNARTVDSVL--LNG-CKHPVETLYIDEAFACHAGTLRALIAIIRPKKAVLC 812
Query 5724 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5783
GDP Q + K E V RRC + VS L YD
Sbjct 813 GDPKQCGFFNMMCLKVHFNHEICTQVFHK----------SISRRCTKSVTSVVSTLFYDK 862
Query 5784 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5843
+++ + + I D + + + ++ LT W K + I Y
Sbjct 863 RMRTTNPRDS---------KIEIDTTGSTKPKKDDLI---LTCFRGWVKQLQID-YK--- 906
Query 5844 AVASKILGLPTQTVDSSQGSEYDYVI---FTQTTETAHSCNVNRFNVAITRAKVGIL 5897
G T +SQG V + ++ NV +TR + I+
Sbjct 907 -------GNEIMTAAASQGLTRKGVYAVRYKVNENPLYAPTSEHVNVLLTRTEDKIV 956
>sp|O59182|Y1513_PYRHO Uncharacterized protein PH1513 OS=Pyrococcus
horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974
/ NBRC 100139 / OT-3) OX=70601 GN=PH1513 PE=4 SV=1
Length=190
Score = 110 bits (275), Expect = 2e-25, Method: Composition-based stats.
Identities = 43/180 (24%), Positives = 71/180 (39%), Gaps = 32/180 (18%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESD----DYIAT 1093
I DI + + +VNAAN YL+HGGGVA A+ KA + + + +
Sbjct 5 FKIVRGDITK----FRAEAIVNAANKYLEHGGGVAYAIAKAASGDVSEYTRISKEEMRRQ 60
Query 1094 NGP--LKVGGSCVLSGHNL----AKHCLHVVGPNVNK---GEDIQLLKSAYENFNQH--- 1141
G ++ G V L K+ +H VGP + + LK A +
Sbjct 61 LGKDWIEHGEVVVTPPMKLKENGVKYVIHTVGPYCGGVWSKDKEEKLKLAILGALKKADE 120
Query 1142 ---EVLLAPLLSAGIFGADPIHSLRVCVDTVRT---------NVYLAVFDKNLYDKLVSS 1189
+ + P +SAGI+G +R + V+ VYL ++ + Y + +
Sbjct 121 LGVKSIAFPAISAGIYGCPLKEVVRTFKEVVKEFLKVANHVKEVYLVLYSERDYKLALET 180
>sp|Q09820|RENT1_SCHPO ATP-dependent helicase upf1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=upf1
PE=3 SV=2
Length=925
Score = 120 bits (300), Expect = 4e-25, Method: Composition-based stats.
Identities = 83/405 (20%), Positives = 144/405 (36%), Gaps = 102/405 (25%)
Query 5599 QKYSTLQGPPGTGKS----HFAIGLALYYPSAR-----IVYTACSHAAVDALCEKALK-- 5647
+ S +QGPPGTGK+ LA R ++ A S+ AVD L EK +
Sbjct 407 KPLSLIQGPPGTGKTVTSASVVYHLATMQSRKRKSHSPVLVCAPSNVAVDQLAEKIHRTG 466
Query 5648 ----------YLPIDKCSRIIPARARVECFDKFKV------------NSTLEQ------- 5678
I+ + +++ + KF N Q
Sbjct 467 LRVVRVAAKSREDIESSVSFLSLHEQIKNY-KFNPELQRLLKLRSENNELSIQDEKKLRI 525
Query 5679 --------------YVFCT-VNA----LPETTADIVVFDEISMATNYDLSVVNARLRAKH 5719
+ CT V A + + V+ DE + A+ + ++ L AK
Sbjct 526 LVAAAEKELLRAAHVICCTCVGAGDRRISKYKFRSVLIDEATQASEPEC-MIPLVLGAKQ 584
Query 5720 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMF-LGTCRRCPAEIVDTVSA 5778
V +GD QL P + K L S+ + +G F L R + + S
Sbjct 585 VVLVGDHQQL-GPVVMNKKVALA-SLSQSLFERLIILGNSPFRLVVQYRMHPCLSEFPSN 642
Query 5779 LVYDNKLKAHKDKSAQCFKM-------------FYKGVITHDVSSA----INRPQIG--- 5818
Y+ L+ S + + FY ++S++ +NR +
Sbjct 643 TFYEGTLQNGVTTSERIARHVDFPWIQPDSPLMFYANFGQEELSASGTSFLNRTEASTCE 702
Query 5819 -VVREFLTRNPAWRKAVFISPYNSQNAVASKIL------------GLPTQTVDSSQGSEY 5865
+V FL N + ++PY+ Q + + + + +VD+ QG E
Sbjct 703 KIVTTFLRSNVLPEQIGIVTPYDGQRSYIVQYMQNNGSMQKDLYKAVEVASVDAFQGREK 762
Query 5866 DYVIFTQTTETAH-----SCNVNRFNVAITRAKVGILCIMSDRDL 5905
D++I + + H + R NVA+TRAK G++ + + + L
Sbjct 763 DFIILSCVRSSEHQGIGFVNDPRRLNVALTRAKYGVIVLGNPKVL 807
>sp|A2AKX3|SETX_MOUSE Probable helicase senataxin OS=Mus musculus
OX=10090 GN=Setx PE=1 SV=1
Length=2646
Score = 120 bits (300), Expect = 8e-25, Method: Composition-based stats.
Identities = 59/263 (22%), Positives = 94/263 (36%), Gaps = 46/263 (17%)
Query 5695 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK 5754
V+ DE + + ++ R + +GDP QLP T+++ E Y S+
Sbjct 2154 VIVDEAGQSCEVE-TLSPLIHRCNKLILVGDPKQLPP--TVISMKAQEYGYDQSMMARFC 2210
Query 5755 TIG------------PDMFLGTCRRCPAEIVDTVSALVYDNKLKAHK-DKSAQC------ 5795
+ P + L R +I S VY+ LK ++ +S +C
Sbjct 2211 KLLEENVEQNMIGRLPVLQLTIQYRMHPDICLFPSNYVYNKNLKTNRLTESIRCSSEWPF 2270
Query 5796 ----FKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV------FISPYNSQNAV 5845
G D S IN +I +V E + RK + I+ Y +Q +
Sbjct 2271 QPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKEKRKDISFRNIGIITHYKAQKTM 2330
Query 5846 ASKILG--------LPTQTVDSSQGSEYDYVIFT------QTTETAHSCNVNRFNVAITR 5891
K L TVD+ QG + D +I T ++ R NV ITR
Sbjct 2331 IQKDLEKEFDKKGPAEVDTVDAFQGRQKDCIIVTCVRASAVQGSIGFLASLQRLNVTITR 2390
Query 5892 AKVGILCIMSDRDLYDKLQFTSL 5914
AK + + R L + + L
Sbjct 2391 AKYSLFILGHLRTLMENQHWYEL 2413
Score = 40.4 bits (93), Expect = 0.91, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 26/64 (41%), Gaps = 18/64 (28%)
Query 5600 KYSTLQGPPGTGKSHFAIGL------------------ALYYPSARIVYTACSHAAVDAL 5641
K + GPPGTGKS +GL R++ A S+AAVD L
Sbjct 1933 KICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENFNAKIKQNRVLVCAPSNAAVDEL 1992
Query 5642 CEKA 5645
+K
Sbjct 1993 MKKI 1996
>sp|P26627|R1AB_CVMJD Replicase polyprotein 1ab (Fragment) OS=Murine
coronavirus (strain defective JHM) OX=11143 GN=rep PE=3
SV=1
Length=500
Score = 115 bits (289), Expect = 1e-24, Method: Composition-based stats.
Identities = 45/178 (25%), Positives = 72/178 (40%), Gaps = 38/178 (21%)
Query 2 ESLVPGFNEKTHVQLS---LPVLQ-------VRDVLVRGFGDSVEEVLSEARQHLKDGTC 51
E V G HV++ LP L+ +RD+ V + ++V + L+ G+
Sbjct 46 EPKVKGKTLVNHVRVDCSRLPALECCVQSAIIRDIFV---DEDPQKVEASTMMALQFGSA 102
Query 52 GLVEVEK----------GVLPQLEQPYVFIKRSDARTAP---HGHVMVEL-VAELEGIQY 97
LV+ K GVLP+ +F + T HV +L + +G+
Sbjct 103 VLVKPSKRLSVQAWAKLGVLPKTPAMGLFKRFCLCNTRECVCDAHVAFQLFTVQPDGVCL 162
Query 98 GRSGETLGVLVPHVGEIPVAYRK------VLLRKNGNKG---AGGHSYGADLKSFDLG 146
G +G +G VP V IP ++ +LLRK GNKG +G + +D
Sbjct 163 G-NGRFIGWFVP-VTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHSRRAVTMPVYDFN 218
Score = 50.1 bits (118), Expect = 7e-04, Method: Composition-based stats.
Identities = 43/195 (22%), Positives = 75/195 (38%), Gaps = 21/195 (11%)
Query 1603 DVTKIKPHNSHEGKTFYVLPNDDT-LRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQV 1661
D+ K++ E +T P D T V AF+ + L + + + +K
Sbjct 323 DIEKVEDSILSELQTELNAPADKTYEDVLAFDAIY---SETLSAFYAVPSDETHFKVC-- 377
Query 1662 NGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKT 1721
G S NC+L + L+ +Q + L+F +Q + +AG F ++ K+
Sbjct 378 -GFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKLVKSAPKS 436
Query 1722 VGEL--GDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQF 1779
+ G V + + S K N C CG + L+G++AV + G +
Sbjct 437 IILPQGGYVADFAYFFLSQ---CSFKVHANWRCLKCGM-ELKLQGLDAVFFYGDV----- 487
Query 1780 KKGVQIPCTCGKQAT 1794
V C C +A
Sbjct 488 ---VSHMCKCSFKAY 499
>sp|Q9FJR0|RENT1_ARATH Regulator of nonsense transcripts 1 homolog
OS=Arabidopsis thaliana OX=3702 GN=UPF1 PE=1 SV=2
Length=1254
Score = 118 bits (296), Expect = 1e-24, Method: Composition-based stats.
Identities = 81/421 (19%), Positives = 138/421 (33%), Gaps = 104/421 (25%)
Query 5582 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSAR-----IVYTACSHA 5636
+ + +S V + V + S +QGPPGTGK+ A+ Y A+ ++ A S+
Sbjct 486 LPELNASQVNAVKSVLQKPISLIQGPPGTGKT--VTSAAIVYHMAKQGQGQVLVCAPSNV 543
Query 5637 AVDAL--------------CEKALKYLPIDK----------------------------- 5653
AVD L C K+ + +
Sbjct 544 AVDQLAEKISATGLKVVRLCAKSREAVSSPVEYLTLHYQVRHLDTSEKSELHKLQQLKDE 603
Query 5654 ----CSRIIPARARVECFDKFKVNSTLEQYVFCTVNA----LPETTADIVVFDEISMATN 5705
S ++ + ++ + + V A L V+ DE + AT
Sbjct 604 QGELSSSDEKKYKNLKRATEREITQSADVICCTCVGAADLRLSNFRFRQVLIDESTQATE 663
Query 5706 YDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPD-MFLGT 5764
+ ++ L K V +GD QL ++ K S+ + T+G + L
Sbjct 664 PEC-LIPLVLGVKQVVLVGDHCQLGP--VIMCKKAARAGLAQSLFERLVTLGIKPIRLQV 720
Query 5765 CRRCPAEIVDTVSALVYDNKLK---------------AHKDKSAQCFKMFYKGVITHDVS 5809
R + + S Y+ L+ + F G S
Sbjct 721 QYRMHPALSEFPSNSFYEGTLQNGVTIIERQTTGIDFPWPVPNRPMFFYVQLGQEEISAS 780
Query 5810 --SAINRPQIGVVREFLTRNPAWRKAVF------ISPYNSQNAVASKILG---------- 5851
S +NR + V + +T + V I+PY Q A +
Sbjct 781 GTSYLNRTEAANVEKLVTAF--LKSGVVPSQIGVITPYEGQRAYIVNYMARNGSLRQQLY 838
Query 5852 --LPTQTVDSSQGSEYDYVIF-TQTTE----TAHSCNVNRFNVAITRAKVGILCIMSDRD 5904
+ +VDS QG E DY+I + + R NVA+TRA+ GI+ + + +
Sbjct 839 KEIEVASVDSFQGREKDYIILSCVRSNEHQGIGFLNDPRRLNVALTRARYGIVILGNPKV 898
Query 5905 L 5905
L
Sbjct 899 L 899
>sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens
OX=9606 GN=SETX PE=1 SV=4
Length=2677
Score = 118 bits (296), Expect = 2e-24, Method: Composition-based stats.
Identities = 64/289 (22%), Positives = 99/289 (34%), Gaps = 54/289 (19%)
Query 5695 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK 5754
V+ DE + + ++ R + +GDP QLP T+++ E Y S+
Sbjct 2178 VIVDEAGQSCEIE-TLTPLIHRCNKLILVGDPKQLPP--TVISMKAQEYGYDQSMMARFC 2234
Query 5755 TIG------------PDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSA-QC------ 5795
+ P + L R +I S VY+ LK ++ A +C
Sbjct 2235 RLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSDWPF 2294
Query 5796 ----FKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV------FISPYNSQNAV 5845
G D S IN +I +V E + RK V I+ Y +Q +
Sbjct 2295 QPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFRNIGIITHYKAQKTM 2354
Query 5846 ASKILG--------LPTQTVDSSQGSEYDYVIF------TQTTETAHSCNVNRFNVAITR 5891
K L TVD+ QG + D VI + ++ R NV ITR
Sbjct 2355 IQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITR 2414
Query 5892 AKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVI 5940
AK + + R L + + L A+ + K C K
Sbjct 2415 AKYSLFILGHLRTLMENQHWNQLIQD--------AQKRGAIIKTCDKNY 2455
Score = 40.4 bits (93), Expect = 0.91, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 26/64 (41%), Gaps = 18/64 (28%)
Query 5600 KYSTLQGPPGTGKSHFAIGL------------------ALYYPSARIVYTACSHAAVDAL 5641
K + GPPGTGKS +GL R++ A S+AAVD L
Sbjct 1957 KICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDEL 2016
Query 5642 CEKA 5645
+K
Sbjct 2017 MKKI 2020
>sp|A0A1P8ASY1|JHS1_ARATH DNA replication ATP-dependent helicase/nuclease
JHS1 OS=Arabidopsis thaliana OX=3702 GN=JHS1 PE=2
SV=1
Length=1331
Score = 118 bits (295), Expect = 2e-24, Method: Composition-based stats.
Identities = 79/371 (21%), Positives = 140/371 (38%), Gaps = 70/371 (19%)
Query 5599 QKYSTLQGPPGTGKSHFAI--GLALYYPSARIVYTACSHAAVDALCEK----ALKYLPID 5652
+ Y+ + G PGTGK+ + AL + I+ + +++AVD L K +++L I
Sbjct 938 KDYALILGMPGTGKTSTMVHAVKALLIRGSSILLASYTNSAVDNLLIKLKAQGIEFLRIG 997
Query 5653 KCSRIIPARARVECFD----------KFKVNSTLEQYVFCT-VNA--LPETTADIVVFDE 5699
+ + R CF K K++ C +N+ L D+ + DE
Sbjct 998 R-DEAVHEEVRESCFSAMNMCSVEDIKKKLDQVKVVASTCLGINSPLLVNRRFDVCIIDE 1056
Query 5700 ISMATNYDLSVVNARLR-AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGP 5758
L V L A +V +GD QLP + + E S+ R + P
Sbjct 1057 AGQIA---LPVSIGPLLFASTFVLVGDHYQLPP--LVQSTEARENGMGISLFRRLSEAHP 1111
Query 5759 DM--FLGTCRRCPAEIVDTVSALVYDN------------------------KLKAHKDKS 5792
L R I++ +AL+Y + LK + +
Sbjct 1112 QAISVLQNQYRMCRGIMELSNALIYGDRLCCGSAEVADATLVLSTSSSTSPWLKKVLEPT 1171
Query 5793 AQCFKMFYKGVITHDVSS--AINRPQ-----IGVVREFLTRNPAWRKAVFISPYNSQNAV 5845
+ + + AIN P +V E + + I+PYNSQ ++
Sbjct 1172 RTVVFVNTDMLRAFEARDQNAINNPVEASIIAEIVEELVNNGVDSKDIGIITPYNSQASL 1231
Query 5846 ---ASKILGLPTQTVDSSQGSEYDYVIFT--------QTTETAHSCNVNRFNVAITRAKV 5894
A + T+D QG + D ++ + +++ ++ + +R NVA+TRAK
Sbjct 1232 IQHAIPTTPVEIHTIDKYQGRDKDCILVSFVRSREKPRSSASSLLGDWHRINVALTRAKK 1291
Query 5895 GILCIMSDRDL 5905
++ + S R L
Sbjct 1292 KLIMVGSQRTL 1302
>sp|Q8QHA5|DNA2_XENLA DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Xenopus laevis OX=8355 GN=dna2 PE=1 SV=1
Length=1053
Score = 117 bits (293), Expect = 3e-24, Method: Composition-based stats.
Identities = 71/393 (18%), Positives = 123/393 (31%), Gaps = 87/393 (22%)
Query 5599 QKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLP------ 5650
+ Y+ + G PGTGK+ + LY ++ T+ +H+AVD + K K+
Sbjct 642 KDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLKKFQVGFLRLG 701
Query 5651 -----IDKCSRIIPARA----RVECFDKFKV--NSTLEQYVFCT---VNALPETTADIVV 5696
++ + NS C D +
Sbjct 702 RTQKLHPDVQEFSEEEICKAKSIKSLSALEELYNSQPVVATTCMGVNHPIFTRRRFDFCI 761
Query 5697 FDEISMATNYDLSVVNARL-RAKHYVYIGDPAQLPA--PRTLLTKGTLEPEYFNSVCRLM 5753
DE S + + L A +V +GD QLP + + F + R
Sbjct 762 VDEASQISQ---PICLGPLFFADRFVLVGDHQQLPPLVKSAEARELGMSESLFKRLERNQ 818
Query 5754 KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD----------------------- 5790
+ + L R ++I+ + LVY+ +L+ D
Sbjct 819 EAVVQ---LTVQYRMNSKIMALSNKLVYEGRLECASDRVSNAVVQLPHIKTLLLELEFRE 875
Query 5791 -------------KSAQCFKMFYK--GVITHDVSSAINRPQIGVV----REFLTRNPAWR 5831
+ CF K + T + N + +V + +L
Sbjct 876 SQESMWIKDVLEPSNPVCFLNTEKIPALETEEKGGISNWIEAKLVFHLTKLYLKAGCRPS 935
Query 5832 KAVFISPYNSQ-----NAVAS-KILGLPTQTVDSSQGSEYDYVIFT-QTTET-----AHS 5879
I+PY Q N S + TVD QG + +I + +
Sbjct 936 DIGIIAPYRQQLKMISNYFNSLSASAVEVNTVDKYQGRDKSVIIVSFVRSNIDGKLGDLL 995
Query 5880 CNVNRFNVAITRAKVGILCIMSDRDL--YDKLQ 5910
+ R NVA+TRAK ++ + L +D L+
Sbjct 996 KDWRRLNVALTRAKHKLIMLGCVPTLNRFDCLE 1028
>sp|P38935|SMBP2_HUMAN DNA-binding protein SMUBP-2 OS=Homo sapiens
OX=9606 GN=IGHMBP2 PE=1 SV=3
Length=993
Score = 115 bits (288), Expect = 1e-23, Method: Composition-based stats.
Identities = 87/415 (21%), Positives = 136/415 (33%), Gaps = 112/415 (27%)
Query 5599 QKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVD------ALCEKALKYLP 5650
++ + + GPPGTGK+ I L +++ A S+ AVD ALC++ + L
Sbjct 207 KELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNIAVDNLVERLALCKQRILRLG 266
Query 5651 ID-------------------KCSRIIPARARVECFDKFKVNS----------------- 5674
++I+ A R + F N
Sbjct 267 HPARLLESIQQHSLDAVLARSDSAQIV-ADIRKDIDQVFVKNKKTQDKREKSNFRNEIKL 325
Query 5675 -----------------TLEQYVFCT---------VNALPETTADIVVFDEISMATNYDL 5708
T V T + LPE+ D+VV DE + A +
Sbjct 326 LRKELKEREEAAMLESLTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQA--LEA 383
Query 5709 SVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPD--MFLGTCR 5766
S L+A+ + GD QLP P T+ K L + + RL + G L
Sbjct 384 SCWIPLLKARKCILAGDHKQLP-PTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQY 442
Query 5767 RCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVS--------SAINRPQIG 5818
R I+ S +Y +L AH + + T + + ++
Sbjct 443 RMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVPLLLVDTAGCGLFELE 502
Query 5819 VVREFLTRNP------------------AWRKAVFISPYNSQNAVASKIL-----GLPTQ 5855
E NP R +SPYN Q + + L L +
Sbjct 503 EEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRHPELEIK 562
Query 5856 TVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
+VD QG E + VI + + E R NVA+TRA+ + I R +
Sbjct 563 SVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTV 617
>sp|P30771|RENT1_YEAST ATP-dependent helicase NAM7 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=NAM7
PE=1 SV=1
Length=971
Score = 115 bits (287), Expect = 1e-23, Method: Composition-based stats.
Identities = 95/513 (19%), Positives = 173/513 (34%), Gaps = 123/513 (24%)
Query 5489 LSWEVGKPRPPLNRNYVFTGYRVTKNSKV-----QIGEYTFEKGDYGDAVVYRGTTTYKL 5543
L + K PP + FT + K + + ++ +K + Y+
Sbjct 330 LELKPSKTPPPTHLTTGFTAEFIWKGTSYDRMQDALKKFAIDKKSISGYLYYK------- 382
Query 5544 NVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYST 5603
+ H V+ +S +P+E + P + SN V + S
Sbjct 383 -------ILGHQVVDISFDVPLPKEFSI------PNFAQLNSSQSNAV--SHVLQRPLSL 427
Query 5604 LQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAAVDALCEK----ALKYLPIDKCS 5655
+QGPPGTGK+ L+ + RI+ A S+ AVD L K LK + + S
Sbjct 428 IQGPPGTGKTVTSATIVYHLSKIH-KDRILVCAPSNVAVDHLAAKLRDLGLKVVRLTAKS 486
Query 5656 R--------------IIPARARVECFDKFKVNS-------------------------TL 5676
R ++ A+ E + K+
Sbjct 487 REDVESSVSNLALHNLVGRGAKGELKNLLKLKDEVGELSASDTKRFVKLVRKTEAEILNK 546
Query 5677 EQYVFCTVNALPETTADI----VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAP 5732
V CT + D V+ DE + A+ + ++ AK + +GD QL
Sbjct 547 ADVVCCTCVGAGDKRLDTKFRTVLIDESTQASEPEC-LIPIVKGAKQVILVGDHQQLGP- 604
Query 5733 RTLLTKGTLEPEYFNSVCRLMKTIGPD-MFLGTCRRCPAEIVDTVSALVYDNKLKAHKDK 5791
+L + + S+ + ++G + L R + + S + Y+ L+
Sbjct 605 -VILERKAADAGLKQSLFERLISLGHVPIRLEVQYRMNPYLSEFPSNMFYEGSLQNGVTI 663
Query 5792 SAQCFKM-----------------FYKGVITHDVSSAINRPQIGVVREFLTRN-----PA 5829
+ + + I+ + +S +NR + +T+
Sbjct 664 EQRTVPNSKFPWPIRGIPMMFWANYGREEISANGTSFLNRIEAMNCERIITKLFRDGVKP 723
Query 5830 WRKAVFISPYNSQNAV------------ASKILGLPTQTVDSSQGSEYDYVIFT-----Q 5872
+ V I+PY Q A + + +VD+ QG E DY+I + +
Sbjct 724 EQIGV-ITPYEGQRAYILQYMQMNGSLDKDLYIKVEVASVDAFQGREKDYIILSCVRANE 782
Query 5873 TTETAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
+ R NV +TRAK G++ + + R L
Sbjct 783 QQAIGFLRDPRRLNVGLTRAKYGLVILGNPRSL 815
>sp|O28751|Y1521_ARCFU ADP-ribose glycohydrolase AF_1521 OS=Archaeoglobus
fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628
/ NBRC 100126 / VC-16) OX=224325 GN=AF_1521 PE=1 SV=2
Length=192
Score = 103 bits (257), Expect = 6e-23, Method: Composition-based stats.
Identities = 44/179 (25%), Positives = 68/179 (38%), Gaps = 30/179 (17%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNA---MQVESDD-YIAT 1093
+ + DI + +VNAAN L+HGGGVA A+ KA S
Sbjct 14 LKLAQGDITQ----YPAKAIVNAANKRLEHGGGVAYAIAKACAGDAGLYTEISKKAMREQ 69
Query 1094 NGP--LKVGGSCVLSGHNL----AKHCLHVVGPNVNKGEDIQLLKSAYENFN-------- 1139
G + G V NL K+ H VGP + +L + Y+ F
Sbjct 70 FGRDYIDHGEVVVTPAMNLEERGIKYVFHTVGPICSGMWSEELKEKLYKAFLGPLEKAEE 129
Query 1140 -QHEVLLAPLLSAGIFGADPIHSLRVCVDTVR-------TNVYLAVFDKNLYDKLVSSF 1190
E + P +SAGI+G D + ++ V+ V L ++D+ + + F
Sbjct 130 MGVESIAFPAVSAGIYGCDLEKVVETFLEAVKNFKGSAVKEVALVIYDRKSAEVALKVF 188
>sp|O76512|RENT1_CAEEL Regulator of nonsense transcripts 1 OS=Caenorhabditis
elegans OX=6239 GN=smg-2 PE=1 SV=1
Length=1069
Score = 113 bits (282), Expect = 6e-23, Method: Composition-based stats.
Identities = 84/415 (20%), Positives = 145/415 (35%), Gaps = 95/415 (23%)
Query 5582 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAA 5637
+ + SS + ++V + S +QGPPGTGK+ L ++ + S+ A
Sbjct 443 LPELNSSQMQAVKQVLTRPLSLIQGPPGTGKTVVSATIVYHLVQKTEGN-VLVCSPSNIA 501
Query 5638 VDALCEKALKY--LPIDKCSR-------IIPA---------------------------- 5660
VD L EK K + C+R +P
Sbjct 502 VDHLAEKIHKTGLKVVRLCARSREHSETTVPYLTLQHQLKVMGGAELQKLIQLKDEAGEL 561
Query 5661 ----RARVECFDKFKVNS--TLEQYVFCTVNA-----LPETTADIVVFDEISMATNYDLS 5709
R + K + + CT ++ L + V+ DE + AT ++
Sbjct 562 EFKDDLRYMQLKRVKEHELLAAADVICCTCSSAADARLSKIRTRTVLIDESTQATEPEIL 621
Query 5710 VVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMF-LGTCRRC 5768
V R + V +GD QL ++ K S+ + +G F L R
Sbjct 622 VSIMR-GVRQLVLVGDHCQLGP--VVICKKAAIAGLSQSLFERLVLLGIRPFRLQVQYRM 678
Query 5769 PAEIVDTVSALVYDNKLKAHKDKSAQ---------------CFKMFYKGVITHDVS--SA 5811
+ + S + YD L+ ++ + F G S S
Sbjct 679 HPVLSEFPSNVFYDGSLQNGVTENDRHMTGVDWHWPKPNKPAFFWHCSGSEELSASGTSF 738
Query 5812 INRPQIGVVREFLTRN-----PAWRKAV---------FISPY-NSQNAVASKIL-GLPTQ 5855
+NR + V + +++ + V FI Y ++Q + SK+ +
Sbjct 739 LNRTEAANVEKLVSKLIKAGVQPHQIGVITSYEGQRSFIVNYMHTQGTLNSKLYENVEIA 798
Query 5856 TVDSSQGSEYDYVIF-TQTTE----TAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
+VD+ QG E DY+I + + R NVAITRAK G++ + + + L
Sbjct 799 SVDAFQGREKDYIIVTCVRSNDILGIGFLSDPRRLNVAITRAKYGLVLVGNAKVL 853
>sp|F1RCY6|RENT1_DANRE Regulator of nonsense transcripts 1 OS=Danio
rerio OX=7955 GN=upf1 PE=2 SV=1
Length=1100
Score = 113 bits (282), Expect = 6e-23, Method: Composition-based stats.
Identities = 80/418 (19%), Positives = 142/418 (34%), Gaps = 100/418 (24%)
Query 5582 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSAR-----IVYTACSHA 5636
+ D S V + V + S +QGPPGTGK+ + Y AR ++ A S+
Sbjct 448 LPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKT--VTSATIVYHLARQGNGPVLVCAPSNI 505
Query 5637 AVDAL--------------CEKALKYLPIDKCSRIIPARARV------------------ 5664
AVD L C K+ + + + + R
Sbjct 506 AVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETG 565
Query 5665 -------ECFDKFKVNST-----LEQYVFCT-VNA----LPETTADIVVFDEISMATNYD 5707
+ + K + + CT V A L + ++ DE + AT +
Sbjct 566 ELSSSDEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPE 625
Query 5708 LSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIG-PDMFLGTCR 5766
+V L AK + +GD QL ++ K + S+ + +G + L
Sbjct 626 C-MVPVVLGAKQLILVGDHCQLGP--VVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQY 682
Query 5767 RCPAEIVDTVSALVYDNKLKAHK---------------DKSAQCFKMFYKGVITHDVS-- 5809
R + S + Y+ L+ F +G S
Sbjct 683 RMHPALSAFPSNIFYEGSLQNGVTAADRLKKGFDFQWPQPDKPMFFYVTQGQEEIASSGT 742
Query 5810 SAINRPQIGVVREFLTR-----NPAWRKAVFISPYNSQNAVASKIL------------GL 5852
S +NR + V + TR + + I+PY Q + + + +
Sbjct 743 SYLNRTEAANVEKITTRLLKAGAKPDQIGI-ITPYEGQRSYLVQYMQFSGSLHTKLYQEV 801
Query 5853 PTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
+VD+ QG E D++I + + + R NVA+TRA+ G++ + + + L
Sbjct 802 EIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKAL 859
>sp|Q9EPU0|RENT1_MOUSE Regulator of nonsense transcripts 1 OS=Mus
musculus OX=10090 GN=Upf1 PE=1 SV=2
Length=1124
Score = 112 bits (281), Expect = 8e-23, Method: Composition-based stats.
Identities = 79/418 (19%), Positives = 142/418 (34%), Gaps = 100/418 (24%)
Query 5582 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSAR-----IVYTACSHA 5636
+ D S V + V + S +QGPPGTGK+ + Y AR ++ A S+
Sbjct 474 LPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKT--VTSATIVYHLARQGNGPVLVCAPSNI 531
Query 5637 AVDAL--------------CEKALKYLPIDKCSRIIPARARV------------------ 5664
AVD L C K+ + + + + R
Sbjct 532 AVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETG 591
Query 5665 -------ECFDKFKVNST-----LEQYVFCT-VNA----LPETTADIVVFDEISMATNYD 5707
+ + K + + CT V A L + ++ DE + AT +
Sbjct 592 ELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPE 651
Query 5708 LSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIG-PDMFLGTCR 5766
+V L AK + +GD QL ++ K + S+ + +G + L
Sbjct 652 C-MVPVVLGAKQLILVGDHCQLGP--VVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQY 708
Query 5767 RCPAEIVDTVSALVYDNKLKAHK---------------DKSAQCFKMFYKGVITHDVS-- 5809
R + S + Y+ L+ F +G S
Sbjct 709 RMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGT 768
Query 5810 SAINRPQIGVVREFLTR-----NPAWRKAVFISPYNSQNAVASKIL------------GL 5852
S +NR + V + T+ + + I+PY Q + + + +
Sbjct 769 SYLNRTEAANVEKITTKLLKAGAKPDQIGI-ITPYEGQRSYLVQYMQFSGSLHTKLYQEV 827
Query 5853 PTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
+VD+ QG E D++I + + + R NVA+TRA+ G++ + + + L
Sbjct 828 EIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKAL 885
>sp|Q92900|RENT1_HUMAN Regulator of nonsense transcripts 1 OS=Homo
sapiens OX=9606 GN=UPF1 PE=1 SV=2
Length=1129
Score = 112 bits (281), Expect = 8e-23, Method: Composition-based stats.
Identities = 79/418 (19%), Positives = 142/418 (34%), Gaps = 100/418 (24%)
Query 5582 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSAR-----IVYTACSHA 5636
+ D S V + V + S +QGPPGTGK+ + Y AR ++ A S+
Sbjct 479 LPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKT--VTSATIVYHLARQGNGPVLVCAPSNI 536
Query 5637 AVDAL--------------CEKALKYLPIDKCSRIIPARARV------------------ 5664
AVD L C K+ + + + + R
Sbjct 537 AVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETG 596
Query 5665 -------ECFDKFKVNST-----LEQYVFCT-VNA----LPETTADIVVFDEISMATNYD 5707
+ + K + + CT V A L + ++ DE + AT +
Sbjct 597 ELSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPE 656
Query 5708 LSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIG-PDMFLGTCR 5766
+V L AK + +GD QL ++ K + S+ + +G + L
Sbjct 657 C-MVPVVLGAKQLILVGDHCQLGP--VVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQY 713
Query 5767 RCPAEIVDTVSALVYDNKLKAHK---------------DKSAQCFKMFYKGVITHDVS-- 5809
R + S + Y+ L+ F +G S
Sbjct 714 RMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGT 773
Query 5810 SAINRPQIGVVREFLTR-----NPAWRKAVFISPYNSQNAVASKIL------------GL 5852
S +NR + V + T+ + + I+PY Q + + + +
Sbjct 774 SYLNRTEAANVEKITTKLLKAGAKPDQIGI-ITPYEGQRSYLVQYMQFSGSLHTKLYQEV 832
Query 5853 PTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
+VD+ QG E D++I + + + R NVA+TRA+ G++ + + + L
Sbjct 833 EIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKAL 890
>sp|Q54I89|RENT1_DICDI Regulator of nonsense transcripts 1 OS=Dictyostelium
discoideum OX=44689 GN=upf1 PE=3 SV=1
Length=1331
Score = 112 bits (280), Expect = 1e-22, Method: Composition-based stats.
Identities = 93/482 (19%), Positives = 164/482 (34%), Gaps = 106/482 (22%)
Query 5526 KGDYGDAVVYRGTTTYKLNVGD-YFVLTSHTVMP------LSAPTLVPQEHYVRITGLYP 5578
KG Y +V+R T++ ++ F + + L P + P +++ +
Sbjct 471 KGSYRMEMVWRSTSSERILSAMKSFAIKEQALSSYLYHALLGHPDIPPAPLDIQLPTNFH 530
Query 5579 TLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS---HFAIG-LALYYPSA-RIVYTAC 5633
N+ S ++ KV S +QGPPGTGK+ F I L Y +++
Sbjct 531 LKNLPRLNESQISAVNKVLTAPLSLIQGPPGTGKTVISSFIIHHLVKYVKGNDKVLVCTP 590
Query 5634 S--------------------------------------HAAVDALCE------------ 5643
S H V L +
Sbjct 591 SNVAIDQLTGKLHEIGLKVVRLSSKLREEVASPVEHLTLHKQVYKLDQMGDGELGKLRKL 650
Query 5644 -KALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM 5702
+A L + R I R +E K + V L + ++ DE +
Sbjct 651 KEAFGSLSNEDEKRYIYLRRMMEMAILRKADVICATCVGAGDPRLSQFRFPHILIDESTQ 710
Query 5703 ATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIG--PDM 5760
A+ + ++ + AK + +GD QL LL K ++ S+ + ++G P+
Sbjct 711 ASEPEC-LIPLMMGAKQVILVGDHRQLGP--VLLCKKVVDAGLSQSLFERLISLGHHPER 767
Query 5761 FLGTCRRCPAEIVDTVSALVYDNKLKA---HKDKSAQ-----------CFKMFYKGVITH 5806
L R + + S Y+ +L + H D+ +Q F G
Sbjct 768 -LTIQYRMHPSLTEFPSNTSYEGQLVSELSHTDRDSQSKFPWPQPKDPMFFFNCTGSEEI 826
Query 5807 DVS--SAINRPQIGVVREFLTRNPAWRKAV----FISPYNSQNAVASKIL---------- 5850
S S IN + + + +T+ I+PY Q A + +
Sbjct 827 SSSGTSFINTTEASICEKIVTKFLELGSLPGQIGIITPYEGQRAYITSHMQKSGKLNLEL 886
Query 5851 --GLPTQTVDSSQGSEYDYVIF-TQTTE----TAHSCNVNRFNVAITRAKVGILCIMSDR 5903
+ +VDS QG E DY+I + + R NVA+TRA+ G++ + + +
Sbjct 887 YKSIEVASVDSFQGREKDYIILSCVRSNDYQGIGFLQDPRRLNVALTRARFGLIILGNAK 946
Query 5904 DL 5905
L
Sbjct 947 VL 948
>sp|Q57568|Y104_METJA Uncharacterized ATP-dependent helicase MJ0104
OS=Methanocaldococcus jannaschii (strain ATCC 43067 /
DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) OX=243232 GN=MJ0104
PE=3 SV=1
Length=663
Score = 111 bits (277), Expect = 1e-22, Method: Composition-based stats.
Identities = 53/247 (21%), Positives = 94/247 (38%), Gaps = 38/247 (15%)
Query 5692 ADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCR 5751
D++V DE S A + S + ++ + + GD QLP P L L+ F + +
Sbjct 395 FDVIVIDEGSQA--MEPSCLIPIVKGRKLIMAGDHKQLP-PTVLSENEELKKTLFERLIK 451
Query 5752 LMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVI------- 5804
L R +I++ + + Y+NKLKA + K
Sbjct 452 KYPEFSS--ILEIQYRMNEKIMEFPNKMFYNNKLKADESVKNITLLDLVKEEEIDEVDRD 509
Query 5805 ------------------THDVSSAINRPQIGVVREFLTRNPAWRKAV-FISPYNSQNAV 5845
+ S N + V E + + ++ I+PY++Q
Sbjct 510 IINEIPVQFINVEGIERKDKESPSYYNIEEAEKVLEIVKKLVKYKIPTNVITPYDAQVRY 569
Query 5846 ASKI-----LGLPTQTVDSSQGSEYDYVI--FTQTTETAHSCNVNRFNVAITRAKVGILC 5898
++ + + TVD QG E + ++ F +T ++ R NVAITRAK ++
Sbjct 570 LRRLFEEHNIDIEVNTVDGFQGRENEAIVISFVRTKNFGFLKDLRRLNVAITRAKRKLIL 629
Query 5899 IMSDRDL 5905
I ++ L
Sbjct 630 IGNENLL 636
Score = 40.8 bits (94), Expect = 0.60, Method: Composition-based stats.
Identities = 22/83 (27%), Positives = 39/83 (47%), Gaps = 9/83 (11%)
Query 5584 DEFSSNVANYQKVGMQKYST------LQGPPGTGKS---HFAIGLALYYPSARIVYTACS 5634
+ + N+ QK+ ++K + GPPGTGK+ I + + +++ TA S
Sbjct 179 EFYDKNLNESQKLAVKKAVLSRDLYLIHGPPGTGKTRTITEVIVQEVKFNKHKVLATADS 238
Query 5635 HAAVDALCEKALKYLPIDKCSRI 5657
+ A D + E +K P K R+
Sbjct 239 NIAADNILEYLIKKYPDLKVVRV 261
>sp|Q0VGT4|ZGRF1_MOUSE 5'-3' DNA helicase ZGRF1 OS=Mus musculus
OX=10090 GN=Zgrf1 PE=1 SV=2
Length=1863
Score = 109 bits (273), Expect = 1e-21, Method: Composition-based stats.
Identities = 52/248 (21%), Positives = 89/248 (36%), Gaps = 29/248 (12%)
Query 5682 CTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTL 5741
C L + +VV DE S T + AR + + + +GDP QLP P +
Sbjct 1554 CAFPCLNDLKFPVVVLDECSQMTEPASLLPIARFQCEKLILVGDPKQLP-PTIQGSDAAH 1612
Query 5742 EPEYFNSVCRLMKTIGPD-MFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ------ 5794
E ++ + +G + L T RC I + L Y+ L + +
Sbjct 1613 ENGLEQTLFDRLCLMGHKPVLLRTQYRCHPAISAIANDLFYEGSLVNGISERERSPVLEW 1672
Query 5795 ----CFKMFYKGVITHDVSSAINRPQIGV----VREFLTRNPAWRKAVFISPYNSQNAVA 5846
CF +S +N + ++ + I+ Y SQ
Sbjct 1673 LPTLCFYNVTGAEQVERENSFVNVAEATFTLKLIQSLMASGVESCMIGVITLYKSQMYKI 1732
Query 5847 SKILG-----------LPTQTVDSSQGSEYDYVIFT--QTTETAHSCNVNRFNVAITRAK 5893
+L + TVD+ QG+E + I + +T + + R NVA+TR +
Sbjct 1733 CNLLSAVDVGHPDVKAVQVSTVDAFQGAEKEITILSCVRTRQVGFIDSEKRMNVALTRGR 1792
Query 5894 VGILCIMS 5901
+L + S
Sbjct 1793 RHLLIVGS 1800
>sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 OS=Arabidopsis
thaliana OX=3702 GN=SDE3 PE=1 SV=1
Length=1002
Score = 107 bits (267), Expect = 3e-21, Method: Composition-based stats.
Identities = 86/410 (21%), Positives = 134/410 (33%), Gaps = 86/410 (21%)
Query 5604 LQGPPGTGKS-HFAIGLALYYPS---ARIVYTACSHAAVDALCEKALKYLPID-KCSRII 5658
+ GPPGTGK+ + Y + AR++ A S++A D + EK L + K + I
Sbjct 419 IHGPPGTGKTMTLVEAIVQLYTTQRNARVLVCAPSNSAADHILEKLLCLEGVRIKDNEIF 478
Query 5659 PARARVECFDKFKVN---------------------------STLEQYVFCTVNALPETT 5691
A +++ K ST +
Sbjct 479 RLNAATRSYEEIKPEIIRFCFFDELIFKCPPLKALTRYKLVVSTYMSASLLNAEGVNRGH 538
Query 5692 ADIVVFDEISMA--TNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV 5749
++ DE A ++V N L V GDP QL + ++ S
Sbjct 539 FTHILLDEAGQASEPENMIAVSNLCLTETVVVLAGDPRQLGP--VIYSRDAESLGLGKSY 596
Query 5750 CRLMKTI-----GPDMF---LGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQC------ 5795
+ G + + L RC EI+D S L YD +L A K+ +
Sbjct 597 LERLFECDYYCEGDENYVTKLVKNYRCHPEILDLPSKLFYDGELVASKEDTDSVLASLNF 656
Query 5796 -----FKMFYKG-----VITHDVSSAINRPQIGVVREFLTRNP-----AWRKAVFISPYN 5840
F M + G + S NR +I V E + R I+PY
Sbjct 657 LPNKEFPMVFYGIQGCDEREGNNPSWFNRIEISKVIETIKRLTANDCVQEEDIGVITPYR 716
Query 5841 SQNAVASKILG------LPTQTVDSSQGSEYDYVIFTQTTET------------AHSCNV 5882
Q ++L + +V+ QG E +I + T N
Sbjct 717 QQVMKIKEVLDRLDMTEVKVGSVEQFQGQEKQVIIISTVRSTIKHNEFDRAYCLGFLSNP 776
Query 5883 NRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGL 5932
RFNVAITRA ++ I + + + + L + Q GL
Sbjct 777 RRFNVAITRAISLLVIIGNPHIICKDMNWNKLLWRCVDNNAYQG---CGL 823
>sp|Q8U0P9|Y1536_PYRFU Uncharacterized protein PF1536 OS=Pyrococcus
furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
OX=186497 GN=PF1536 PE=4 SV=1
Length=183
Score = 96.7 bits (239), Expect = 1e-20, Method: Composition-based stats.
Identities = 43/181 (24%), Positives = 71/181 (39%), Gaps = 32/181 (18%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVE---SDD-YIAT 1093
+ + DI + + +VNAAN YL+HGGGVA A+ KA ++ S +
Sbjct 2 IKVVKGDITK----FRAEAIVNAANKYLEHGGGVAYAIAKAAAGDVREYIRISKEAMREQ 57
Query 1094 NGP--LKVGGSCVLSGHNL----AKHCLHVVGPNVNKG---EDIQLLKSAYENFNQH--- 1141
G + G V L K+ +H VGP + LK A +
Sbjct 58 LGKDWIDHGEVVVTPPLQLEKNGVKYVIHTVGPYCGGSWDEDKKSKLKLAILGALKKADE 117
Query 1142 ---EVLLAPLLSAGIFGADPIHSLRVCVDTVRT---------NVYLAVFDKNLYDKLVSS 1189
+ + P +SAGI+G + V+ V+ V+L ++ + Y+K +
Sbjct 118 LGVKSIAFPAISAGIYGCPLEKVVETFVEVVKEFLPSAKSLREVFLVLYSQEDYEKALKI 177
Query 1190 F 1190
Sbjct 178 V 178
>sp|O94247|HCS1_SCHPO DNA polymerase alpha-associated DNA helicase
A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
OX=284812 GN=hcs1 PE=3 SV=1
Length=660
Score = 104 bits (259), Expect = 1e-20, Method: Composition-based stats.
Identities = 84/426 (20%), Positives = 137/426 (32%), Gaps = 118/426 (28%)
Query 5596 VGMQKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVD-------------- 5639
+ +++ S + GPPGTGK+H I L + RI+ S+ AVD
Sbjct 222 IAVKELSLIHGPPGTGKTHTLVEIIQQLVLRNKRILVCGASNLAVDNIVDRLSSSGIPMV 281
Query 5640 ----------ALCEKALKYLP---------------IDKC-SRIIPARARVEC------- 5666
++ + +L L ID C S+I + E
Sbjct 282 RLGHPARLLPSILDHSLDVLSRTGDNGDVIRGISEDIDVCLSKITKTKNGRERREIYKNI 341
Query 5667 ------FDKFKVNS-----TLEQYVFCTVNA-----LPETTADIVVFDEISMATNYDLSV 5710
+ K++ + + + VFCT++ L D V+ DE S A
Sbjct 342 RELRKDYRKYEAKTVANIVSASKVVFCTLHGAGSRQLKGQRFDAVIIDEASQALE-PQCW 400
Query 5711 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDM---FLGTCRR 5767
+ L + GD QL +P + S+ + D+ FL R
Sbjct 401 IPL-LGMNKVILAGDHMQL-SPNV------QSKRPYISMFERLVKSQGDLVKCFLNIQYR 452
Query 5768 CPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAI-------NRPQ---- 5816
I S YD+KL ++ + T S I N +
Sbjct 453 MHELISKFPSDTFYDSKLVPAEEVKKRLLMDLENVEETELTDSPIYFYDTLGNYQEDDRS 512
Query 5817 --------------------IGVVREFLTRNPAWRKAVFISPYNSQNAVASKIL---GLP 5853
+ L + ++PYN+Q A+ ++L G+
Sbjct 513 EDMQNFYQDSKSNHWEAQIVSYHISGLLEAGLEAKDIAVVTPYNAQVALIRQLLKEKGIE 572
Query 5854 TQ--TVDSSQGSEYDYVIFTQTT-----ETAHSCNVNRFNVAITRAKVGILCIMSDRDLY 5906
+ +VD QG E + +IF+ E R NVAITR K + I +
Sbjct 573 VEMGSVDKVQGREKEAIIFSLVRSNDVREVGFLAEKRRLNVAITRPKRHLCVIGDSNTVK 632
Query 5907 DKLQFT 5912
+F
Sbjct 633 WASEFF 638
>sp|Q86YA3|ZGRF1_HUMAN 5'-3' DNA helicase ZGRF1 OS=Homo sapiens
OX=9606 GN=ZGRF1 PE=1 SV=3
Length=2104
Score = 105 bits (262), Expect = 2e-20, Method: Composition-based stats.
Identities = 52/248 (21%), Positives = 92/248 (37%), Gaps = 31/248 (13%)
Query 5682 CTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTL 5741
C + + +VV DE S T + AR + + +GDP QLP P +
Sbjct 1793 CPFPCMNDLKFPVVVLDECSQITEPASLLPIARFECEKLILVGDPKQLP-PTIQGSDAAH 1851
Query 5742 EPEYFNSVCRLMKTIGPD-MFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ------ 5794
E ++ + +G + L T RC I + L Y L + +
Sbjct 1852 ENGLEQTLFDRLCLMGHKPILLRTQYRCHPAISAIANDLFYKGALMNGVTEIERSPLLEW 1911
Query 5795 ----CFKMFYKGVITHDVSSAINRP-----QIGVVREFLTRNPAWRKAVFISPYNSQNAV 5845
CF KG+ + ++ + + +++ + A I+ Y SQ
Sbjct 1912 LPTLCFYN-VKGLEQIERDNSFHNVAEATFTLKLIQSLIASGIAGSMIGVITLYKSQMYK 1970
Query 5846 ASKIL-----------GLPTQTVDSSQGSEYDYVIFT--QTTETAHSCNVNRFNVAITRA 5892
+L + TVD+ QG+E + +I + +T + + R NVA+TR
Sbjct 1971 LCHLLSAVDFHHPDIKTVQVSTVDAFQGAEKEIIILSCVRTRQVGFIDSEKRMNVALTRG 2030
Query 5893 KVGILCIM 5900
K +L +
Sbjct 2031 KRHLLIVG 2038
>sp|Q5JER1|Y1890_THEKO Uncharacterized protein TK1890 OS=Thermococcus
kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OX=69014 GN=TK1890 PE=4 SV=1
Length=180
Score = 95.5 bits (236), Expect = 3e-20, Method: Composition-based stats.
Identities = 42/176 (24%), Positives = 69/176 (39%), Gaps = 32/176 (18%)
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVE---SDD-YIATNG 1095
I DI + +VNAAN YL+HGGGVA A+ KA + S + G
Sbjct 6 IVKGDIT----RFPAEAIVNAANRYLEHGGGVAYAIAKAAAGDPREYIRISKEAMREQLG 61
Query 1096 P--LKVGGSCVLSGHNLAKH----CLHVVGPNVN---KGEDIQLLKSAYENFNQH----- 1141
++ G V L KH +H VGP + + L+ A +
Sbjct 62 KDHIEHGEVVVTPAMRLEKHGIRYVIHTVGPYCGGIWDEDKKEKLRKAILGALRKAEELG 121
Query 1142 -EVLLAPLLSAGIFGADPIHSLRVCVDTVR---------TNVYLAVFDKNLYDKLV 1187
+ + P +SAGI+G ++ + + VYL ++ + Y++ +
Sbjct 122 VKTIAFPAVSAGIYGCPLEEVVKTFKEVIDEFEREAGSVERVYLVLYSEKDYERAL 177
>sp|P34243|HCS1_YEAST DNA polymerase alpha-associated DNA helicase
A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=HCS1 PE=1 SV=1
Length=683
Score = 101 bits (252), Expect = 1e-19, Method: Composition-based stats.
Identities = 53/269 (20%), Positives = 93/269 (35%), Gaps = 51/269 (19%)
Query 5688 PETTADIVVFDEISMA--TNYDLSVVNARLRAKHYVYIGDPAQLPAPR----TLLTKGTL 5741
D ++ DE+S A + ++ + + V GD QLP L
Sbjct 385 NFQLFDTLIIDEVSQAMEPQCWIPLIAHQNQFHKLVLAGDNKQLPPTIKTEDDKNVIHNL 444
Query 5742 EPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKL---------------- 5785
E F+ + ++ FL R +I++ S +Y+ KL
Sbjct 445 ETTLFDRIIKIFPKRDMVKFLNVQYRMNQKIMEFPSHSMYNGKLLADATVANRLLIDLPT 504
Query 5786 ---KAHKDKSAQCFKMFY---KGVITHDV-------SSAINRPQIGVVREFLTR----NP 5828
+D + + +G + S N +I +V+E + N
Sbjct 505 VDATPSEDDDDTKIPLIWYDTQGDEFQETADEATILGSKYNEGEIAIVKEHIENLRSFNV 564
Query 5829 AWRKAVFISPYNSQNAVASKIL-------GLPTQTVDSSQGSEYDYVIFT-----QTTET 5876
ISPYN+Q + K++ + TVD QG E D +I + + E
Sbjct 565 PENSIGVISPYNAQVSHLKKLIHDELKLTDIEISTVDGFQGREKDVIILSLVRSNEKFEV 624
Query 5877 AHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
R NVA+TR + ++ + + L
Sbjct 625 GFLKEERRLNVAMTRPRRQLVVVGNIEVL 653
Score = 42.0 bits (97), Expect = 0.26, Method: Composition-based stats.
Identities = 28/101 (28%), Positives = 43/101 (43%), Gaps = 10/101 (10%)
Query 5562 PTLVPQEHYVRITG-LYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLA 5620
P + + I L P LN S + + N A + + GPPGTGK+ I L
Sbjct 189 PFIPNTNSFQNIKSFLNPNLNDSQKTAINFAI-----NNDLTIIHGPPGTGKTFTLIELI 243
Query 5621 ----LYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRI 5657
+ P RI+ S+ +VD + E+ +P + RI
Sbjct 244 QQLLIKNPEERILICGPSNISVDTILERLTPLVPNNLLLRI 284
>sp|P0DC29|ADPRH_STRPQ Protein-ADP-ribose hydrolase OS=Streptococcus
pyogenes serotype M3 (strain SSI-1) OX=193567 GN=SPs1056
PE=3 SV=1
Length=270
Score = 95.1 bits (235), Expect = 3e-19, Method: Composition-based stats.
Identities = 31/150 (21%), Positives = 59/150 (39%), Gaps = 22/150 (15%)
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKH-----GGGVAGALNKATNNAMQVESDDYIATN 1094
+ + DI + + +VNAAN L G + A++ + +++ +
Sbjct 88 LYHGDI----RYLAVDAIVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQ 143
Query 1095 G-PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ-----LLKSAYENFN------QH 1141
G +G + + S ++L A + +H VGP + KG + LL Y +
Sbjct 144 GRKEAIGQAKLTSAYHLPASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGL 203
Query 1142 EVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
L +S G FG + ++ + TV
Sbjct 204 TSLAFCSISTGEFGFPKKEAAQIAIKTVLK 233
>sp|P0DC28|ADPRH_STRP3 Protein-ADP-ribose hydrolase OS=Streptococcus
pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)
OX=198466 GN=SpyM3_0856 PE=3 SV=1
Length=270
Score = 95.1 bits (235), Expect = 3e-19, Method: Composition-based stats.
Identities = 31/150 (21%), Positives = 59/150 (39%), Gaps = 22/150 (15%)
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKH-----GGGVAGALNKATNNAMQVESDDYIATN 1094
+ + DI + + +VNAAN L G + A++ + +++ +
Sbjct 88 LYHGDI----RYLAVDAIVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQ 143
Query 1095 G-PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ-----LLKSAYENFN------QH 1141
G +G + + S ++L A + +H VGP + KG + LL Y +
Sbjct 144 GRKEAIGQAKLTSAYHLPASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGL 203
Query 1142 EVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
L +S G FG + ++ + TV
Sbjct 204 TSLAFCSISTGEFGFPKKEAAQIAIKTVLK 233
>sp|Q99ZI6|ADPRH_STRP1 Protein-ADP-ribose hydrolase OS=Streptococcus
pyogenes serotype M1 OX=301447 GN=SPy_1216 PE=3 SV=1
Length=270
Score = 95.1 bits (235), Expect = 3e-19, Method: Composition-based stats.
Identities = 31/150 (21%), Positives = 59/150 (39%), Gaps = 22/150 (15%)
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKH-----GGGVAGALNKATNNAMQVESDDYIATN 1094
+ + DI + + +VNAAN L G + A++ + +++ +
Sbjct 88 LYHGDI----RYLAVDAIVNAANSELLGCFSPNHGCIDNAIHTFAGSRLRLACQAIMTEQ 143
Query 1095 G-PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ-----LLKSAYENFN------QH 1141
G +G + + S ++L A + +H VGP + KG + LL Y +
Sbjct 144 GRKEAIGQAKLTSAYHLPASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGL 203
Query 1142 EVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
L +S G FG + ++ + TV
Sbjct 204 TSLAFCSISTGEFGFPKKEAAQIAIKTVLK 233
>sp|Q4QXJ8|POLN_EEEVF Polyprotein P1234 OS=Eastern equine encephalitis
virus (strain Florida 91-469) OX=374598 PE=1 SV=3
Length=2494
Score = 101 bits (251), Expect = 4e-19, Method: Composition-based stats.
Identities = 51/268 (19%), Positives = 94/268 (35%), Gaps = 47/268 (18%)
Query 1039 YIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLK 1098
+ DI + V+VNAAN + G GV GAL + A + P+
Sbjct 1332 RVVRGDITKS----NDEVIVNAANNKGQPGSGVCGALYRKWPGAFDKQ---------PVA 1378
Query 1099 VGGSCVLSGHNLAKHCLHVVGP---NVNKGEDIQLLKSAYE------NFNQHEVLLAPLL 1149
G + ++ + + +H VGP +++ E Q L Y N + + PLL
Sbjct 1379 TGKAHLVKH---SPNVIHAVGPNFSRLSENEGDQKLSEVYMDIARIINNERFTKVSIPLL 1435
Query 1150 SAGIFGA------DPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKI 1203
S GI+ ++ L +DT ++ + DK ++ + +S +++ +
Sbjct 1436 STGIYAGGKDRVMQSLNHLFTAMDTTDADITIYCLDKQWESRIKEAITRKESVEELTEDD 1495
Query 1204 AEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGNL 1263
+ E V S+ R +V + LE T+F I +
Sbjct 1496 RPVDIELV---RVHPLSSLAGRPGYS----TTEGKVYSYLEGTRF--HQTAKDIAEIYAM 1546
Query 1264 HPDSATL-------VSDIDITFLKKDAP 1284
P+ V + ++ P
Sbjct 1547 WPNKQEANEQICLYVLGESMNSIRSKCP 1574
Score = 56.6 bits (135), Expect = 1e-05, Method: Composition-based stats.
Identities = 58/297 (20%), Positives = 90/297 (30%), Gaps = 62/297 (21%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS G+ + R L A K + C II R
Sbjct 717 VYGVPGSGKS----GIIKSAVTKR------------DLVVSAKK----ENCMEIIKDVKR 756
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5723
+ D +N + + + D + DE L + A ++ K V
Sbjct 757 MRGMDI-----AARTVDSVLLNGV-KHSVDTLYIDEAFACHAGTLLALIAIVKPKKVVLC 810
Query 5724 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5783
GDP Q + K E V RRC + VS L YD
Sbjct 811 GDPKQCGFFNMMCLKVHFNHEICTEVYHK----------SISRRCTKTVTSIVSTLFYDK 860
Query 5784 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5843
+++ I D +S + ++ LT W K + I Y +
Sbjct 861 RMRTVNP---------CNDKIIIDTTSTTKPLKDDII---LTCFRGWVKQLQID-YKNH- 906
Query 5844 AVASKILGLPTQTVDSSQGSEYDYVI---FTQTTETAHSCNVNRFNVAITRAKVGIL 5897
T +SQG V + ++ NV +TR + I+
Sbjct 907 ---------EIMTAAASQGLTRKGVYAVRYKVNENPLYAQTSEHVNVLLTRTEKRIV 954
>sp|Q1LXK5|M10B2_DANRE Putative helicase mov-10-B.2 OS=Danio rerio
OX=7955 GN=mov10b.2 PE=3 SV=1
Length=1015
Score = 100 bits (249), Expect = 4e-19, Method: Composition-based stats.
Identities = 85/465 (18%), Positives = 147/465 (32%), Gaps = 125/465 (27%)
Query 5548 YFVLTSHTVMPLSAPTL--------VPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQ 5599
F + S ++ P+S P L + Y + + + +
Sbjct 505 LFPMASRSLNPVSPPALRLFDRKLEYNFQQYSAVCNIVAGTSKPAPY------------- 551
Query 5600 KYSTLQGPPGTGKSHFAI----GLALYYPSARIVYTACSHAAVDALCEK----------- 5644
+ GPPGTGK+ + + P A I+ A S++A D LCEK
Sbjct 552 ---LVFGPPGTGKTVTIVEAIKQVEKNIPDAYILACAPSNSAADQLCEKLITSEHVDAHK 608
Query 5645 ALKYLPIDKCSRIIPARARVECFDK-------FKVNSTLEQYVFCTV--------NALPE 5689
+ + + IP + C K + + + CT+ E
Sbjct 609 IYRLYASSRNQKDIPKILKDNCNVDEEMIDFPCKEDLMSYKILICTLVTAGRLVTGGFSE 668
Query 5690 TTADIVVFDEISMATNYDLSV-VNARLRAK--HYVYIGDPAQL------PAPRTLLTKGT 5740
DE A + + V L A+ V GDP QL P +
Sbjct 669 DHFTHNFVDEAGHAVESETIISVAGLLNAEKGQLVLAGDPKQLGPILRSPLAINHGLDVS 728
Query 5741 LEPEYF--NSVCRLMKTIGPDMFLGTC---RRCPAEIVDTVSALVYDNKLKAHKDK---S 5792
L N + + + ++ R I++ + L YD +LKA D+ +
Sbjct 729 LLERLMTQNDLYKRGDVEFDNRYVSKLIMNYRSHPYILEVPNRLFYDGELKACADEISSN 788
Query 5793 AQC---------FKMFYKG-----VITHDVSSAINRPQIGVVREFLTR------------ 5826
C F + + G + S N +I ++ ++L +
Sbjct 789 QYCMWEHLPSKGFPVIFHGVPGKDERESNSPSFFNIYEINILVDYLKKLLLTQPKKGISR 848
Query 5827 -NPAWRKAVFISPYNSQNAVASKILG-------------LPTQTVDSSQGSEYDYVIFT- 5871
P I+PY Q + + L +V+ QG E ++ +
Sbjct 849 IFPKDIG--IIAPYRKQVEKIKRAIDADKDFQDYMGIDNLKVGSVEEFQGQERKVIMVST 906
Query 5872 -----------QTTETAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
+T N RFNVA+TRAK ++ + + L
Sbjct 907 VRSSVKYISLDETFNIGFLKNEKRFNVAVTRAKSLLIMVGNPMIL 951
>sp|Q8P0X2|ADPRH_STRP8 Protein-ADP-ribose hydrolase OS=Streptococcus
pyogenes serotype M18 (strain MGAS8232) OX=186103 GN=spyM18_1168
PE=3 SV=1
Length=270
Score = 94.8 bits (234), Expect = 4e-19, Method: Composition-based stats.
Identities = 31/150 (21%), Positives = 59/150 (39%), Gaps = 22/150 (15%)
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKH-----GGGVAGALNKATNNAMQVESDDYIATN 1094
+ + DI + + +VNAAN L G + A++ + +++ +
Sbjct 88 LYHGDI----RYLAVDAIVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQ 143
Query 1095 G-PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ-----LLKSAYENFN------QH 1141
G +G + + S ++L A + +H VGP + KG + LL Y +
Sbjct 144 GRKEAIGQAKLTSAYHLPASYIIHTVGPRITKGRHVSPIRADLLARCYRSSLDLAVKAGL 203
Query 1142 EVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
L +S G FG + ++ + TV
Sbjct 204 TSLAFCSISTGEFGFPKKEAAQIAIKTVLK 233
>sp|Q5XC09|ADPRH_STRP6 Protein-ADP-ribose hydrolase OS=Streptococcus
pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)
OX=286636 GN=M6_Spy0919 PE=3 SV=1
Length=270
Score = 94.4 bits (233), Expect = 5e-19, Method: Composition-based stats.
Identities = 31/150 (21%), Positives = 59/150 (39%), Gaps = 22/150 (15%)
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKH-----GGGVAGALNKATNNAMQVESDDYIATN 1094
+ + DI + + +VNAAN L G + A++ + +++ +
Sbjct 88 LYHGDI----RYLAVDAIVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQ 143
Query 1095 G-PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ-----LLKSAYENFN------QH 1141
G +G + + S ++L A + +H VGP + KG + LL Y +
Sbjct 144 GRKEAIGQAKLTSAYHLPASYIIHTVGPRITKGRHVSPIRADLLARCYRSSLDLAVKAGL 203
Query 1142 EVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
L +S G FG + ++ + TV
Sbjct 204 TSLAFCSISTGEFGFPKKEAAQIAIKTVLK 233
>sp|Q008X5|R1A_WBV24 Replicase polyprotein 1a OS=White bream virus
(isolate Blicca bjoerkna L./Germany/DF24/00) OX=766180
GN=1a PE=1 SV=1
Length=4555
Score = 100 bits (250), Expect = 5e-19, Method: Composition-based stats.
Identities = 27/96 (28%), Positives = 38/96 (40%), Gaps = 12/96 (13%)
Query 4306 QAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL 4365
AI+ P + ++ G S C C DH C G +VQIP ++ F L
Sbjct 4467 IAISQVPVQTIGYLTYAGISVCRQCATKQDHT-----CQYAGYFVQIPREHVSN--IFNL 4519
Query 4366 KNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLN 4401
+T C K +C L++ QS Q LN
Sbjct 4520 TDT--PPCLHNKFTCTTCQPLQQ---QSKTQQPPLN 4550
Score = 60.1 bits (144), Expect = 1e-06, Method: Composition-based stats.
Identities = 127/798 (16%), Positives = 260/798 (33%), Gaps = 145/798 (18%)
Query 3037 PIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTP 3096
P GA A+++ +V I + Y ++ F Y++ V + ++ L++ ++
Sbjct 3240 PTGASSNVAALLMASVVVISMVLFYLYLLQ---IFKFYTNSVIMSFVIQLLTLLATTVST 3296
Query 3097 VYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWF 3156
+ ++ + Y Y +++ ++ T L+ + I +++ Y
Sbjct 3297 PLAVTVQLFVITYGY--------TNWILLTLSLLNLTVLLSTPVGITFVVIYGLYKAYTL 3348
Query 3157 FSNYLKRRVVFNG---VSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNK 3213
F++ + V G +FE+ A TF L ++L SD+ + Q N Y + ++
Sbjct 3349 FTSSGQGCVYNEGGTIRFSGSFEQVANSTFPLTNASCVQLLSDLGITYQQLNVYASSRDR 3408
Query 3214 YKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPS 3273
+ R A L + L+ S +LY+ S + Q+ R +
Sbjct 3409 -----------NVRRLAQALLHRQLDSASEC---ILYE--GCSGNTITRQALQRIRQAVT 3452
Query 3274 GKVEGCMVQVT-CGTTTLNGLWLD---------DVVYCPRHVICTSEDML---NPNYEDL 3320
V + + NG+ L +++ C H I TS+ Y+
Sbjct 3453 VVVTPASQNLCKITSNQANGIGLSCTGTFFTSTEIITCA-HGIGTSDITAVHKGITYDCK 3511
Query 3321 LIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLAC 3380
+ +N ++ V L V + + + + FV Q ++
Sbjct 3512 VKSINNDIAILITTTVNLSVQNIKLDSSFSQKSDNYQRNFVQFVSFVDQQNSDAVTINN- 3570
Query 3381 YNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 3440
+ G GS + ++ + + G+H G D
Sbjct 3571 ---------TVMLPSGHFFAIGTEAGESGSP-YTLNGNII------------GIHYGIDN 3608
Query 3441 EGNFY------GPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFN 3494
G++ G F T T + + A + A++ T+ N
Sbjct 3609 AGSWMLASRPDGSFYVPATQHGNSAKVTFSTDAFAQQFPAIV--------TNKTSDQLVN 3660
Query 3495 LVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEF 3554
+A N D D V + LK L N + L D
Sbjct 3661 EIAATNN-TAFELDTTD------------VSHLSNLLKHLKNNNETPK------SLSDYL 3701
Query 3555 TPFDVVRQCS---GVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAF 3611
V +Q S G T S V + +L++ + + + L N+
Sbjct 3702 PVAPVTQQTSVTVGQTLTSPVNNMQTALYTLMLVSEVITYI-------------LTPNSD 3748
Query 3612 LPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN-----MVYMPASWVMRIMTW 3666
L + + SAF K + L ++ T + + + + + + I+++
Sbjct 3749 LSVLISMFVTSAFLKFGAS-KLFYNTEMLRNTITTFVVYRYTTLLIALVFSQYYLHILSY 3807
Query 3667 LDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLV--YKVYYG 3724
++T + + V L+L+T R VY + + + +++ +
Sbjct 3808 ALKLNTLVLT-----VIALTFLVTPLVLLTIRRVYYYSQNYLISCVFIISCFASHTYTLY 3862
Query 3725 NALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYC 3784
D + IIS T + L G + V P++ C++ +Y
Sbjct 3863 ILTDTTVDFQTFIIS----EPIFSTLLCNLFIGFTLISVVPNPLYV-------CVVFMYI 3911
Query 3785 F-----LGYFCTCYFGLF 3797
LG+ TC+ +
Sbjct 3912 LLDCEALGFIVTCFMASY 3929
Score = 47.8 bits (112), Expect = 0.006, Method: Composition-based stats.
Identities = 35/159 (22%), Positives = 61/159 (38%), Gaps = 36/159 (23%)
Query 1046 VEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQV-----------ESDDYIATN 1094
+ + +VNAAN L +G GV GA+ A + +++ SD +
Sbjct 1657 IGAITTTEGEFIVNAANKQLNNGTGVTGAIFAAHDKELKLTQAIKALPTYGASDKLESHQ 1716
Query 1095 GPLKVGGSCVLSGHNL--AKHCLHVVGPNV----NKGEDIQL---------LKSAYENF- 1138
++ ++ +N A + LH P +K ++ L LK Y+
Sbjct 1717 HVVQT----IIKNNNSTHAINILHAAAPIKVKCTSKNPEVLLAHNETAQSELKETYKAIV 1772
Query 1139 -----NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTN 1172
N+ + PL AG +G P+ SL +D +R
Sbjct 1773 DYAQLNKLTHIYLPLFGAGAYGHKPLDSLEAFLDAMRNR 1811
Score = 37.7 bits (86), Expect = 5.5, Method: Composition-based stats.
Identities = 49/338 (14%), Positives = 90/338 (27%), Gaps = 59/338 (17%)
Query 2136 DTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTN--SRIKAS 2193
Y + +V Y+ F T T+ T + IKA
Sbjct 2554 SVFLAYIALLYSFSGHGIFTVVAYFTMLFARYYITSFINFCTSQLTATQVTQWFAAIKAK 2613
Query 2194 MPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALG-- 2251
+ + + + Y+ +S ++ + ++ ++ Y+
Sbjct 2614 YTGIYESSQDRVLTVNVTGTNVPYI--VKYSTILTVTMYVAFMAFVWTVSTYAAQYTAGE 2671
Query 2252 ---------VLMSNLGMPSYCTGYREGYLNSTNVTIATYCT--GSIPCSV-CLSGLDSLD 2299
V L + Y ++ + C SI C +
Sbjct 2672 RYDRPPYQTVFQKTLNVLGLTETVTYYYPYAS---LNEACAASTSILCRLGSPFNFHYPS 2728
Query 2300 TYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFI 2359
Y + T+Q SS W LF F L ++
Sbjct 2729 DYTQVRTVQTDTSSPFW----------------LFIIFMPPSFLFIVLPWLILCTITP-- 2770
Query 2360 SNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRAT 2419
+++ Q+ S ++ I F Y K H C TC+ +R+
Sbjct 2771 --------TVSIAQLLVPSIILNATIVF--IYIRRKFTGHC---CGPHTCIKHADISRSL 2817
Query 2420 RVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDT 2457
+ T+ + C HNW C N D+
Sbjct 2818 QFRPTSQIQHSLTFC-------GTLCAKHNWYCNNSDS 2848
>sp|P0DN70|ADPRH_STRPG Protein-ADP-ribose hydrolase OS=Streptococcus
pyogenes serotype M5 (strain Manfredo) OX=160491 GN=SpyM50868
PE=1 SV=1
Length=270
Score = 94.0 bits (232), Expect = 6e-19, Method: Composition-based stats.
Identities = 31/150 (21%), Positives = 59/150 (39%), Gaps = 22/150 (15%)
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKH-----GGGVAGALNKATNNAMQVESDDYIATN 1094
+ + DI + + +VNAAN L G + A++ + +++ +
Sbjct 88 LYHGDI----RYLAVDAIVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQ 143
Query 1095 G-PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ-----LLKSAYENFN------QH 1141
G +G + + S ++L A + +H VGP + KG + LL Y +
Sbjct 144 GRKEAIGQAKLTSAYHLPASYIIHTVGPRITKGRHVSPIRADLLARCYRSSLDLAVKAGL 203
Query 1142 EVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
L +S G FG + ++ + TV
Sbjct 204 TSLAFCSISTGEFGFPKKEAAQIAIKTVLK 233
>sp|Q60560|SMBP2_MESAU DNA-binding protein SMUBP-2 OS=Mesocricetus
auratus OX=10036 GN=IGHMBP2 PE=1 SV=1
Length=989
Score = 99.0 bits (245), Expect = 1e-18, Method: Composition-based stats.
Identities = 62/258 (24%), Positives = 89/258 (34%), Gaps = 43/258 (17%)
Query 5687 LPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYF 5746
LPE D+VV DE + A + S L+A + GD QLP P T+ K L
Sbjct 363 LPENHFDVVVVDECAQA--LEASCWIPLLKAPKCILAGDHRQLP-PTTISHKAALA-GLS 418
Query 5747 NSVCRLMKT---IGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGV 5803
S+ + G L R I S +Y +L AH + K
Sbjct 419 RSLMERLVEKHGAGAVRMLTVQYRMHQAITRWASEAMYHGQLTAHPSVAGHLLKDLPGVA 478
Query 5804 ITHDVS--------SAINRPQIGVVREFLTRNPAWRKAV------------------FIS 5837
T + S + ++ NP + V I+
Sbjct 479 DTEETSVPLLLIDTAGCGLLELDEEDSQSKGNPGEVRLVTLHIQALVDAGVHAGDIAVIA 538
Query 5838 PYNSQNAVASKILG-----LPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNV 5887
PYN Q + + L L ++VD QG E + VI T + E R NV
Sbjct 539 PYNLQVDLLRQSLSNKHPELEIKSVDGFQGREKEAVILTFVRSNRKGEVGFLAEDRRINV 598
Query 5888 AITRAKVGILCIMSDRDL 5905
A+TRA+ + I R +
Sbjct 599 AVTRARRHVAVICDSRTV 616
Score = 44.7 bits (104), Expect = 0.043, Method: Composition-based stats.
Identities = 17/51 (33%), Positives = 27/51 (53%), Gaps = 2/51 (4%)
Query 5596 VGMQKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEK 5644
+ ++ + + GPPGTGK+ I L +I+ A S+ AVD L E+
Sbjct 203 LAQKEVAIIHGPPGTGKTTTVVEIILQAVKQGLKILCCAPSNVAVDNLVER 253
>sp|Q8NYB7|ADPRH_STAAW Protein-ADP-ribose hydrolase OS=Staphylococcus
aureus (strain MW2) OX=196620 GN=MW0302 PE=3 SV=1
Length=266
Score = 92.8 bits (229), Expect = 2e-18, Method: Composition-based stats.
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 21/153 (14%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGG-----VAGALNKATNNAMQVESDDY 1090
DN+++ DI +K +VNAAN + ++ ++++ +
Sbjct 85 DNIFVWQGDIT----TLKIDAIVNAANSRFLGCMQANHDCIDNIIHTKAGVQVRLDCAEI 140
Query 1091 IATNGPLK-VGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ----LLKSAY----ENFNQ 1140
I G + VG + + G+NL AK+ +H VGP + + + LL Y + +Q
Sbjct 141 IRQQGRNEGVGKAKITRGYNLPAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLADQ 200
Query 1141 HEV--LLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
H + + +S G+F + + V TV +
Sbjct 201 HSLNHVAFCCISTGVFAFPQDEAAEIAVRTVES 233
>sp|Q6GCE6|ADPRH_STAAS Protein-ADP-ribose hydrolase OS=Staphylococcus
aureus (strain MSSA476) OX=282459 GN=SAS0302 PE=3 SV=1
Length=266
Score = 92.8 bits (229), Expect = 2e-18, Method: Composition-based stats.
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 21/153 (14%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGG-----VAGALNKATNNAMQVESDDY 1090
DN+++ DI +K +VNAAN + ++ ++++ +
Sbjct 85 DNIFVWQGDIT----TLKIDAIVNAANSRFLGCMQANHDCIDNIIHTKAGVQVRLDCAEI 140
Query 1091 IATNGPLK-VGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ----LLKSAY----ENFNQ 1140
I G + VG + + G+NL AK+ +H VGP + + + LL Y + +Q
Sbjct 141 IRQQGRNEGVGKAKITRGYNLPAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLADQ 200
Query 1141 HEV--LLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
H + + +S G+F + + V TV +
Sbjct 201 HSLNHVAFCCISTGVFAFPQDEAAEIAVRTVES 233
>sp|Q5HIW9|ADPRH_STAAC Protein-ADP-ribose hydrolase OS=Staphylococcus
aureus (strain COL) OX=93062 GN=SACOL0396 PE=3 SV=1
Length=266
Score = 92.8 bits (229), Expect = 2e-18, Method: Composition-based stats.
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 21/153 (14%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGG-----VAGALNKATNNAMQVESDDY 1090
DN+++ DI +K +VNAAN + ++ ++++ +
Sbjct 85 DNIFVWQGDIT----TLKIDAIVNAANSRFLGCMQANHDCIDNIIHTKAGVQVRLDCAEI 140
Query 1091 IATNGPLK-VGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ----LLKSAY----ENFNQ 1140
I G + VG + + G+NL AK+ +H VGP + + + LL Y + +Q
Sbjct 141 IRQQGRNEGVGKAKITRGYNLSAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLADQ 200
Query 1141 HEV--LLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
H + + +S G+F + + V TV +
Sbjct 201 HSLNHVAFCCISTGVFAFPQDEAAEIAVRTVES 233
>sp|Q9URU2|DNA2_SCHPO DNA replication ATP-dependent helicase/nuclease
dna2 OS=Schizosaccharomyces pombe (strain 972 / ATCC
24843) OX=284812 GN=dna2 PE=1 SV=2
Length=1397
Score = 97.4 bits (241), Expect = 4e-18, Method: Composition-based stats.
Identities = 75/382 (20%), Positives = 122/382 (32%), Gaps = 77/382 (20%)
Query 5599 QKYSTLQGPPGTGKSHFAIGL--ALYYPSARIVYTACSHAAVDALCEK-----------A 5645
+ YS + G PGTGK+ L +L +I+ T+ +H AVD + K
Sbjct 947 EHYSLILGMPGTGKTTTISSLIRSLLAKKKKILLTSFTHLAVDNILIKLKGCDSTIVRLG 1006
Query 5646 LKYLPIDKCSRIIPARARV-ECFDKFKVNSTLEQYVFCT-----VNALPETTADIVVFDE 5699
+ + K Q V C+ + + D + DE
Sbjct 1007 SPHKIHPLVKEFCLTEGTTFDDLASLKHFYEDPQIVACSSLGVYHSIFNKRKFDYCIIDE 1066
Query 5700 ISMATNYDLSVVNARLR-AKHYVYIGDPAQLPA--PRTLLTKGTLEPEYFNSVCRLMKTI 5756
S L + L+ A+ +V +GD QLP + +K L F +
Sbjct 1067 ASQ---IPLPICLGPLQLAEKFVLVGDHYQLPPLVKNSRTSKDGLSLSLFKLLSEKHPEA 1123
Query 5757 GPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHK---DKSAQCFKMFYKGVITHDVSSAI- 5812
L R +I S L+Y L + + D SS++
Sbjct 1124 V--TTLRLQYRMNEDINSLSSELIYGGNLVCGSKTISQKKLILPKAHLSDGLPDSSSSLH 1181
Query 5813 --------------------------------NRPQIGVVRE----FLTRNPAWRKAVFI 5836
N + ++ + FL R I
Sbjct 1182 WVNKLINPSHSVIFFNTDDILGVESKTNNILENHTEAFLIEQAVSSFLERGVKQSSIGII 1241
Query 5837 SPYNSQNAVASKIL----GLPTQTVDSSQGSEYDYVIFT-QTTETAHSC-----NVNRFN 5886
S Y SQ + SK L + TVD QG + D ++ + + + + + +R N
Sbjct 1242 SIYKSQVELLSKNLKSFTEIEINTVDRYQGRDKDIILISFVRSNSKNLVGELLRDWHRLN 1301
Query 5887 VAITRAKVGILCIMSDRDLYDK 5908
VA++RAKV + S L
Sbjct 1302 VALSRAKVKCIMFGSLSTLSSS 1323
>sp|A7T167|GDAP2_NEMVE Protein GDAP2 homolog OS=Nematostella vectensis
OX=45351 GN=gdap2 PE=3 SV=1
Length=502
Score = 95.5 bits (236), Expect = 4e-18, Method: Composition-based stats.
Identities = 45/251 (18%), Positives = 87/251 (35%), Gaps = 40/251 (16%)
Query 1010 PQLEMELTPVVQTIE--------VNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAA 1061
P+ P + ++ F ++ V + N DI + + +VN
Sbjct 17 PKWSTTPVPNYEPGSNESQSSSFLSPFPVDEEINAKVVLWNGDITK----LAADAIVNTT 72
Query 1062 NVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGP 1120
N L G ++ +++A + E + G + + G+NL A++ +H VGP
Sbjct 73 NESLSDRGALSERVHRAAGPELMQEC---RQQLLGCRTGEAKISEGYNLPARYVIHTVGP 129
Query 1121 NVN---KGEDIQLLKSAYENF------NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
N K L S Y N N+ + +++ G P + + TVR
Sbjct 130 RYNTKYKTAAESALFSCYRNTMRLVRENKISTIGVCVVNTTKRGYPPEDGAHIALRTVRR 189
Query 1172 ----------NVYLAVFDKN--LYDKLVSSFLEMKSEKQ---VEQKIAEIPKEEVKPFIT 1216
V V +Y K++ + ++ + +I EE +P I
Sbjct 190 FLEKYGSAVDTVAFVVEGAEAVVYAKVMPIYFPRDKLEEAHALTLMPDDIGNEEGEPIIP 249
Query 1217 ESKPSVEQRKQ 1227
E + + +
Sbjct 250 ERQIRIVPKPP 260
>sp|Q6GJZ1|ADPRH_STAAR Protein-ADP-ribose hydrolase OS=Staphylococcus
aureus (strain MRSA252) OX=282458 GN=SAR0322 PE=3 SV=1
Length=266
Score = 91.7 bits (226), Expect = 4e-18, Method: Composition-based stats.
Identities = 32/153 (21%), Positives = 62/153 (41%), Gaps = 21/153 (14%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGG-----VAGALNKATNNAMQVESDDY 1090
DN+++ DI +K +VNAAN + ++ ++++ +
Sbjct 85 DNIFVWQGDIT----TLKIDAIVNAANSRFLGCMQANHDCIDNIIHTKAGVQVRLDCAEI 140
Query 1091 IATNGPLK-VGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQL----LKSAYENFNQH--- 1141
I G + VG + + G+NL AK+ +H VGP + + +L L Y + +
Sbjct 141 IRQQGRNEGVGKAKITRGYNLPAKYIIHTVGPQIRRLPVSKLNQDLLAKCYLSCLKLADQ 200
Query 1142 ---EVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
+ +S G+F + + V TV +
Sbjct 201 QSLNHIAFCCISTGVFAFPQDEAAEIAVRTVES 233
>sp|P67344|ADPRH_STAAN Protein-ADP-ribose hydrolase OS=Staphylococcus
aureus (strain N315) OX=158879 GN=SA0314 PE=1 SV=1
Length=266
Score = 90.9 bits (224), Expect = 8e-18, Method: Composition-based stats.
Identities = 34/153 (22%), Positives = 64/153 (42%), Gaps = 21/153 (14%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGG-----VAGALNKATNNAMQVESDDY 1090
DN+++ DI +K +VNAAN + ++ ++++ +
Sbjct 85 DNIFVWQGDIT----TLKIDAIVNAANSRFLGCMQANHDCIDNIIHTKAGVQVRLDCAEI 140
Query 1091 IATNGPLK-VGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ----LLKSAY----ENFNQ 1140
I G + VG + G+NL AK+ +H VGP + + + LL Y + +Q
Sbjct 141 IRQQGRNEGVGKAKKTRGYNLPAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLADQ 200
Query 1141 HEV--LLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
H + + +S G+F + + V TV +
Sbjct 201 HSLNHVAFCCISTGVFAFPQDEAAEIAVRTVES 233
>sp|P67343|ADPRH_STAAM Protein-ADP-ribose hydrolase OS=Staphylococcus
aureus (strain Mu50 / ATCC 700699) OX=158878 GN=SAV0325
PE=1 SV=1
Length=266
Score = 90.9 bits (224), Expect = 8e-18, Method: Composition-based stats.
Identities = 34/153 (22%), Positives = 64/153 (42%), Gaps = 21/153 (14%)
Query 1036 DNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGG-----VAGALNKATNNAMQVESDDY 1090
DN+++ DI +K +VNAAN + ++ ++++ +
Sbjct 85 DNIFVWQGDIT----TLKIDAIVNAANSRFLGCMQANHDCIDNIIHTKAGVQVRLDCAEI 140
Query 1091 IATNGPLK-VGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQ----LLKSAY----ENFNQ 1140
I G + VG + G+NL AK+ +H VGP + + + LL Y + +Q
Sbjct 141 IRQQGRNEGVGKAKKTRGYNLPAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLADQ 200
Query 1141 HEV--LLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
H + + +S G+F + + V TV +
Sbjct 201 HSLNHVAFCCISTGVFAFPQDEAAEIAVRTVES 233
>sp|Q1LXK4|M10B1_DANRE Putative helicase mov-10-B.1 OS=Danio rerio
OX=7955 GN=mov10b.1 PE=2 SV=2
Length=1013
Score = 95.9 bits (237), Expect = 1e-17, Method: Composition-based stats.
Identities = 81/397 (20%), Positives = 134/397 (34%), Gaps = 101/397 (25%)
Query 5603 TLQGPPGTGKSHFAIGLALYYP----SARIVYTACSHAAVDALCEKALKYLPID--KCSR 5656
+ GPPGTGK+ + ARI+ A S++A D L EK + +D R
Sbjct 547 LVFGPPGTGKTVTIVEAIKQVEKNTGGARILACAPSNSAADQLGEKLITSQHVDARNIYR 606
Query 5657 IIPARARVECFDKFKVNSTLE----------------QYVFCTV--------NALPETTA 5692
I + + K N++ + V CT+ P
Sbjct 607 IYASSRNPKEIPKVLENNSNVEGENIIFPCKEDLMPYKIVVCTLVTAGRLVSGGFPVGHF 666
Query 5693 DIVVFDEISMATNYDLSV-VNARLRAK--HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV 5749
+ DE A ++ + V L A+ V GDP QL L + ++ S+
Sbjct 667 SHIFVDEAGHAVEPEIVISVAGLLNAETGQLVLAGDPKQLGP--ILRSPFAIKYGLGLSL 724
Query 5750 CRLMKTIG----------PDMF---LGTCRRCPAEIVDTVSALVYDNKLKAHKDK----- 5791
+ T + + L R I+ + L YDN+LKA D+
Sbjct 725 LERLMTQNELYQKGDTGFDNRYVTKLLQNYRSHPSILKVPNELFYDNELKACADEISSRQ 784
Query 5792 -------SAQCFKMFYKGVITHD-----VSSAINRPQIGVVREFLTRN--PAWRKAV--- 5834
+ F + + GV+ D S N +I + ++L + +K +
Sbjct 785 YCTWEHLPKRGFPVIFHGVVGKDERESTSPSFFNTSEIDKIMDYLKKLLLTQAKKGIAKI 844
Query 5835 ------FISPYNSQ----------NAVASKILGLP---TQTVDSSQGSEYDYVIFTQ--- 5872
I+PY Q + + G+ +V+ QG E +I +
Sbjct 845 SPKDIGIIAPYRKQVEKIRQAIKIHRELKSLSGIEELKVGSVEEFQGQERKVIIVSTVRS 904
Query 5873 ---------TTETAHSCNVNRFNVAITRAKVGILCIM 5900
N RFNVA+TRAK ++ +
Sbjct 905 SKEHIILDDKFNIGFLKNEKRFNVAVTRAKALLIMVG 941
>sp|O67112|Y987_AQUAE Uncharacterized protein aq_987 OS=Aquifex
aeolicus (strain VF5) OX=224324 GN=aq_987 PE=4 SV=1
Length=165
Score = 87.4 bits (215), Expect = 1e-17, Method: Composition-based stats.
Identities = 31/165 (19%), Positives = 63/165 (38%), Gaps = 27/165 (16%)
Query 1037 NVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGP 1096
++ + I E V V+VN AN GGGVA + + ++ E+ + P
Sbjct 2 DIKVVKGSITE----VDADVIVNPANSRGLMGGGVAVVIKRLGGEEIEREAVE----KAP 53
Query 1097 LKVGGSCVLSGHNLA-KHCLHVVGPNVNK---GEDIQLLKSAYENFNQ------HEVLLA 1146
+ VG + + + L K +H P + + + ++ A + +++
Sbjct 54 IPVGSAVLTTAGKLKFKGVIHA--PTMEEPAMPSSEEKVRKATRAALELADKECFKIVAI 111
Query 1147 PLLSAGIFGADPIHSLRVCVDTVR-------TNVYLAVFDKNLYD 1184
P + G+ G + R V+ +R V L D+ + +
Sbjct 112 PGMGTGVGGVPKEVAARAMVEEIRKFEPKCLEKVILVDIDEEMVE 156
>sp|P32644|ECM32_YEAST Putative ATP-dependent RNA helicase ECM32
OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=ECM32 PE=1 SV=1
Length=1121
Score = 95.9 bits (237), Expect = 1e-17, Method: Composition-based stats.
Identities = 81/441 (18%), Positives = 140/441 (32%), Gaps = 133/441 (30%)
Query 5594 QKVGMQKYSTLQGPPGTGKSHFAIGLALY----YPSARIVYTACSHAAVDALCEKALKYL 5649
+ V + LQGPPGTGK+ + + + + I+ A S+ A+D + EK ++
Sbjct 658 EHVLNNSITILQGPPGTGKTSTIEEIIIQVIERFHAFPILCVAASNIAIDNIAEKIMENR 717
Query 5650 PIDKCSRIIPARARVECFDKFKVNS----------------------------------- 5674
P K RI+ + + D +
Sbjct 718 PQIKILRILSKKKEQQYSDDHPLGEICLHNIVYKNLSPDMQVVANKTRRGEMISKSEDTK 777
Query 5675 -------------TLEQYVFCTVNALP------ETTADIVVFDEISMATNYDLSVVNARL 5715
+ Q +F T A +V+ DE + ++ V +
Sbjct 778 FYKEKNRVTNKVVSQSQIIFTTNIAAGGRELKVIKECPVVIMDEATQSSEASTLVPLSLP 837
Query 5716 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5775
+++V++GD QL + LE F V P + L T R +I +
Sbjct 838 GIRNFVFVGDEKQLSS---FSNIPQLETSLFERVLSNGTYKNP-LMLDTQYRMHPKISEF 893
Query 5776 VSALVYDNKLKAHKDKSAQCFK------MFYKGVITHDVSSAINRPQI------------ 5817
+Y+ +LK + + FY+ + + + I
Sbjct 894 PIKKIYNGELKDGVTDEQKAWPGVQHPLFFYQCDLGPESRVRSTQRDIVGFTYENKHECV 953
Query 5818 GVVR----EFLTRNPAWRKAVFISPYNSQNAVASKIL----------------------- 5850
+V+ L + + I+PY++Q + S IL
Sbjct 954 EIVKIIQILMLDKKVPLEEIGVITPYSAQRDLLSDILTKNVVINPKQISMQQEYDEIELF 1013
Query 5851 ---------------------GLPTQTVDSSQGSEYDYVIF-TQTTET----AHSCNVNR 5884
GL TVDS QG E ++IF T + R
Sbjct 1014 NAAGSQGTAGSLQNNVINIINGLHVATVDSFQGHEKSFIIFSCVRNNTENKIGFLRDKRR 1073
Query 5885 FNVAITRAKVGILCIMSDRDL 5905
NVA+TRAK G++ + + L
Sbjct 1074 LNVALTRAKHGLIVVGNKNVL 1094
>sp|P23249|MOV10_MOUSE Putative helicase MOV-10 OS=Mus musculus
OX=10090 GN=Mov10 PE=1 SV=2
Length=1004
Score = 95.5 bits (236), Expect = 1e-17, Method: Composition-based stats.
Identities = 82/399 (21%), Positives = 130/399 (33%), Gaps = 102/399 (26%)
Query 5604 LQGPPGTGKSHFAI----GLALYYPSARIVYTACSHAAVDALCEKALKYLPID------- 5652
+ GPPGTGK+ + + + P A I+ A S++ D LC++ +LP
Sbjct 523 IFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAP 582
Query 5653 -KCSRIIPARARVEC----------FDKFKVNSTLEQYVFCTVNA-------LPETTADI 5694
+ R++P + C + K + + A P
Sbjct 583 SRDIRMVPEDIKTCCNWDAKKGEYVYPAKKHLQQYRVLITTLITASRLVSAQFPIDHFTH 642
Query 5695 VVFDEISMATNYDLSVVNARLR--------AKHYVYIGDPAQL-PAPRT-LLTKGTLEPE 5744
+ DE + V A L V GDP QL P R+ L K L
Sbjct 643 IFIDEAGHCMEPESLVAIAGLMDVKETGNPGGQLVLAGDPRQLGPVLRSPLALKHGLGYS 702
Query 5745 Y------FNSVCRLMKTIGPDMFLGTC---RRCPAEIVDTVSALVYDNKLK---AHKDKS 5792
+NS+ + F+ R I+D + L YD +L+ D+
Sbjct 703 LLERLLAYNSLYKKGPNGYDPQFITKLLRNYRSHPTILDIPNQLYYDGELQACADVVDRE 762
Query 5793 AQC---------FKMFYKGVITHD-----VSSAINRPQIGVVREFLTR--NPAWRKAV-- 5834
C F + + GV+ D S N + V +L + P+ +K
Sbjct 763 RFCRWEGLPQQGFPIIFHGVMGKDEREGNSPSFFNPEEAATVTSYLKQLLAPSSKKGKAR 822
Query 5835 -------FISPYNSQNAVAS--------------KILGLPTQTVDSSQGSEYDYVIFTQT 5873
ISPY Q I L +V+ QG E ++ +
Sbjct 823 LSPRNVGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTV 882
Query 5874 TETA------------HSCNVNRFNVAITRAKVGILCIM 5900
+ N RFNVA+TRAK ++ +
Sbjct 883 RSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAKALLIVVG 921
>sp|P13896|POLN_WEEV Polyprotein P1234 OS=Western equine encephalitis
virus OX=11039 PE=3 SV=3
Length=2467
Score = 95.9 bits (237), Expect = 2e-17, Method: Composition-based stats.
Identities = 46/192 (24%), Positives = 76/192 (40%), Gaps = 32/192 (17%)
Query 1039 YIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLK 1098
+ DI + A + +VNAAN + G GV GAL + A + P+
Sbjct 1332 RVIRGDISKSADQ----AIVNAANSKGQPGSGVCGALYRKWPAAFDRQ---------PIA 1378
Query 1099 VGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVLLAPLL 1149
VG + ++ L +H VGPN +K + + L +AY N + + PLL
Sbjct 1379 VGTARLVKHEPL---IIHAVGPNFSKMPEPEGDLKLAAAYMSIASIVNAERITKISVPLL 1435
Query 1150 SAGIFGADPIH------SLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQV-EQK 1202
S GI+ L DT +V + DK +++ + +S + + + K
Sbjct 1436 STGIYSGGKDRVMQSLHHLFTAFDTTDADVTIYCLDKQWETRIIEAIHRKESVEILDDDK 1495
Query 1203 IAEIPKEEVKPF 1214
+I V P
Sbjct 1496 PVDIDLVRVHPN 1507
Score = 49.3 bits (116), Expect = 0.002, Method: Composition-based stats.
Identities = 41/208 (20%), Positives = 69/208 (33%), Gaps = 30/208 (14%)
Query 5690 TTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV 5749
+ + DE L + A ++ K V GDP Q + K + V
Sbjct 777 HPVNTLYIDEAFACHAGTLLALIAIVKPKKVVLCGDPKQCGFFNMMCLKVHFNHDICTEV 836
Query 5750 CRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVS 5809
RRC + VS L YD ++K I D +
Sbjct 837 YHK----------SISRRCTQTVTAIVSTLFYDKRMKTVNP---------CADKIIIDTT 877
Query 5810 SAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVI 5869
+ ++ LT W K + I N + A+ GL + V + + + +
Sbjct 878 GTTKPHKDDLI---LTCFRGWVKQLQIDYKNHEIMTAAASQGLTRKGVYAVRYKVNENPL 934
Query 5870 FTQTTETAHSCNVNRFNVAITRAKVGIL 5897
++QT+E NV +TR + I+
Sbjct 935 YSQTSE--------HVNVLLTRTEKRIV 954
>sp|Q9EQN5|SMBP2_RAT DNA-binding protein SMUBP-2 OS=Rattus norvegicus
OX=10116 GN=Ighmbp2 PE=1 SV=1
Length=988
Score = 95.1 bits (235), Expect = 2e-17, Method: Composition-based stats.
Identities = 62/257 (24%), Positives = 90/257 (35%), Gaps = 41/257 (16%)
Query 5687 LPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYF 5746
LPE D+VV DE + A + S L+A + GD QLP P T+ K L
Sbjct 363 LPEDYFDVVVVDECAQA--LEASCWIPLLKAPKCILAGDHKQLP-PTTVSHKAALAGLSR 419
Query 5747 NSVCRLMKTIGP--DMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVI 5804
+ + RL + G L R I S +Y +L AH + K
Sbjct 420 SLMERLAEKHGAAVVRMLAVQYRMHQAITRWASEAMYHGQLTAHPSVAGHLLKDLPGVAD 479
Query 5805 THDVS--------SAINRPQIGVVREFLTRNPAWRKAV------------------FISP 5838
T + S + ++ NP + V I+P
Sbjct 480 TEETSVPLLLIDTAGCGLLELEEEDSQSKGNPGEVRLVTLHIQALVDAGVQAGDIAVIAP 539
Query 5839 YNSQNAVASKILG-----LPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVA 5888
YN Q + + L L ++VD QG E + VI T + E R NVA
Sbjct 540 YNLQVDLLRQSLSNKHPELEIKSVDGFQGREKEAVILTFVRSNRKGEVGFLAEDRRINVA 599
Query 5889 ITRAKVGILCIMSDRDL 5905
+TRA+ + I +
Sbjct 600 VTRARRHVAVICDSHTV 616
Score = 44.3 bits (103), Expect = 0.049, Method: Composition-based stats.
Identities = 16/51 (31%), Positives = 27/51 (53%), Gaps = 2/51 (4%)
Query 5596 VGMQKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEK 5644
+ ++ + + GPPGTGK+ I L +++ A S+ AVD L E+
Sbjct 203 LAQKEVAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNIAVDNLVER 253
>sp|Q306W6|POLN_EEEV1 Polyprotein P1234 OS=Eastern equine encephalitis
virus (strain PE-0.0155) OX=374596 PE=1 SV=3
Length=2471
Score = 95.5 bits (236), Expect = 2e-17, Method: Composition-based stats.
Identities = 53/268 (20%), Positives = 97/268 (36%), Gaps = 47/268 (18%)
Query 1039 YIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLK 1098
+ DI + V+VNAAN + G GV GAL K A P+
Sbjct 1332 RVIRGDISKSTD----EVIVNAANNKGQPGAGVCGALYKKWPGAFDKA---------PIA 1378
Query 1099 VGGSCVLSGHNLAKHCLHVVGPNVNKGEDI---QLLKSAY----ENFNQ--HEVLLAPLL 1149
G + ++ + +H VGPN ++ ++ Q L Y + N+ + + PLL
Sbjct 1379 TGTAHLVKH---TPNIIHAVGPNFSRMSEVEGNQKLSEVYMDIAKIINKERYNKVSIPLL 1435
Query 1150 SAGIFGA------DPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKI 1203
S G++ ++ L +DT +V + DK ++ + +S +++ +
Sbjct 1436 STGVYAGGKDRVMQSLNHLFTAMDTTDADVTIYCLDKQWETRIKDAIARKESVEELVEDD 1495
Query 1204 AEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGNL 1263
+ E V + S+ R +V + LE T+F I +
Sbjct 1496 KPVDIELV---RVHPQSSLVGRPGYSTN----EGKVHSYLEGTRF--HQTAKDIAEIYAM 1546
Query 1264 HPDSATL-------VSDIDITFLKKDAP 1284
P+ V +T ++ P
Sbjct 1547 WPNKQEANEQICLYVLGESMTSIRSKCP 1574
Score = 54.3 bits (129), Expect = 6e-05, Method: Composition-based stats.
Identities = 58/297 (20%), Positives = 89/297 (30%), Gaps = 62/297 (21%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS G+ + R L A K + C+ II R
Sbjct 717 VYGVPGSGKS----GIIKSAVTKR------------DLVVSAKK----ENCTEIIKDVKR 756
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5723
+ D +N + + D + DE L + A ++ K V
Sbjct 757 MRGMDV-----AARTVDSVLLNGV-KHPVDTLYIDEAFACHAGTLLALIAIVKPKKVVLC 810
Query 5724 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5783
GDP Q + K E V RRC + VS L YD
Sbjct 811 GDPKQCGFFNMMCLKVHFNHEICTEVYHK----------SISRRCTRTVTAIVSTLFYDK 860
Query 5784 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5843
+++ I D +S + ++ LT W K + I N
Sbjct 861 RMRTVNP---------CSDKIIIDTTSTTKPLKDDII---LTCFRGWVKQLQIDYKNH-- 906
Query 5844 AVASKILGLPTQTVDSSQGSEYDYVI---FTQTTETAHSCNVNRFNVAITRAKVGIL 5897
T +SQG V + ++ NV +TR + I+
Sbjct 907 ---------EIMTAAASQGLTRKGVYAVRYKVNENPLYAQTSEHVNVLLTRTEKRIV 954
>sp|Q7TZB9|Y1934_MYCBO Uncharacterized protein Mb1934c OS=Mycobacterium
bovis (strain ATCC BAA-935 / AF2122/97) OX=233413
GN=lppD PE=4 SV=1
Length=358
Score = 91.3 bits (225), Expect = 3e-17, Method: Composition-based stats.
Identities = 36/160 (23%), Positives = 63/160 (39%), Gaps = 16/160 (10%)
Query 1022 TIEVNSFSGYLKLTDNVYIKNADIVE-EAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
T + DNV + ++ + + K++ + NAAN L+H GGVA A+ +A
Sbjct 170 TRGASPRPPSTCRGDNVSMIELEVHQADVTKLELDAITNAANTRLRHAGGVAAAIARAGG 229
Query 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHN-LAKHCLHVV-----GPNVNK---GEDIQLL 1131
+Q ES + P+ +G + + + A++ +H GP + L
Sbjct 230 PELQRESTE----KAPIGLGEAVETTAGDMPARYVIHAATMELGGPTSGEIITAATAATL 285
Query 1132 KSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
+ A E L G+ G + R+ V VR
Sbjct 286 RKADE--LGCRSLALVAFGTGVGGFPLDDAARLMVGAVRR 323
>sp|P9WK29|Y1899_MYCTU Uncharacterized protein Rv1899c OS=Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv) OX=83332
GN=Rv1899c PE=1 SV=1
Length=359
Score = 91.3 bits (225), Expect = 3e-17, Method: Composition-based stats.
Identities = 36/160 (23%), Positives = 63/160 (39%), Gaps = 16/160 (10%)
Query 1022 TIEVNSFSGYLKLTDNVYIKNADIVE-EAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
T + DNV + ++ + + K++ + NAAN L+H GGVA A+ +A
Sbjct 171 TRGASPRPPSTCRGDNVSMIELEVHQADVTKLELDAITNAANTRLRHAGGVAAAIARAGG 230
Query 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHN-LAKHCLHVV-----GPNVNK---GEDIQLL 1131
+Q ES + P+ +G + + + A++ +H GP + L
Sbjct 231 PELQRESTE----KAPIGLGEAVETTAGDMPARYVIHAATMELGGPTSGEIITAATAATL 286
Query 1132 KSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
+ A E L G+ G + R+ V VR
Sbjct 287 RKADE--LGCRSLALVAFGTGVGGFPLDDAARLMVGAVRR 324
>sp|Q5ZKD7|MOV10_CHICK Putative helicase MOV-10 OS=Gallus gallus
OX=9031 GN=MOV10 PE=2 SV=1
Length=967
Score = 94.8 bits (234), Expect = 3e-17, Method: Composition-based stats.
Identities = 89/410 (22%), Positives = 133/410 (32%), Gaps = 107/410 (26%)
Query 5603 TLQGPPGTGKSH--FAIGLALYYP--SARIVYTACSHAAVDALCEKALKYLPIDKCSRI- 5657
+ GPPGTGK+ ++ ARI+ A S++A D LC++ L + RI
Sbjct 513 LIFGPPGTGKTVTLVEAIKQVWSCFKDARILACAPSNSAADLLCQRLLTNIAPRYIYRIM 572
Query 5658 --------IPARARVEC----------FDKFKVNSTLEQYVFCTVNA-------LPETTA 5692
+PA R C + K+ + V A P
Sbjct 573 ASSANYKDVPADVRPCCNWDDSEKCYVYPSKKLLKPYRILITTLVTAGRLVSANFPPGYF 632
Query 5693 DIVVFDEISMATNYDLSVVNARL----------RAKHYVYIGDPAQL-PAPRTLLTKGT- 5740
V DE A + V A L V GDP QL P PR+ L
Sbjct 633 SHVFIDECGHAVEPESVVAIAGLLTTMDPDTNPNGGQLVLAGDPQQLGPVPRSPLAAQHG 692
Query 5741 ------LEPEYFNSVCRLMKTIGPDMFLGTC---RRCPAEIVDTVSALVYDNKLKAH--K 5789
N++ F+ R I+ + L YD++LKA+
Sbjct 693 LGTSLLERLMLHNALYAKSDEGYNPQFVTKLLWNYRSHKAILKVPNELFYDSELKAYEGS 752
Query 5790 DKSAQCF------------KMFYKGVITHD-----VSSAINRPQIGVVREFLTR--NPAW 5830
+ + F + + GV D S N +I VV ++L +
Sbjct 753 EPDVRNFYCTWEELPNRGVPIIFHGVCGEDEREAKSPSFFNTAEIEVVVQYLQKLLQSQG 812
Query 5831 RKAV---------FISPYNSQNA-------------VASKILG-LPTQTVDSSQGSEYDY 5867
R+ ISPY Q A +G L +V+ QG E
Sbjct 813 RRGCPTISPKEIGIISPYRKQVEKIRLAITSKDPVLRALPDIGQLKVGSVEEFQGQERRV 872
Query 5868 VIFT------------QTTETAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
++ + QT N R NVA+TRAK ++ + + L
Sbjct 873 ILISTVRSCSEYLQLDQTFRLGFLKNPKRLNVALTRAKALLIVVGNAAVL 922
>sp|P9WK28|Y1899_MYCTO Uncharacterized protein MT1950 OS=Mycobacterium
tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=MT1950
PE=4 SV=1
Length=374
Score = 91.3 bits (225), Expect = 3e-17, Method: Composition-based stats.
Identities = 36/160 (23%), Positives = 63/160 (39%), Gaps = 16/160 (10%)
Query 1022 TIEVNSFSGYLKLTDNVYIKNADIVE-EAKKVKPTVVVNAANVYLKHGGGVAGALNKATN 1080
T + DNV + ++ + + K++ + NAAN L+H GGVA A+ +A
Sbjct 186 TRGASPRPPSTCRGDNVSMIELEVHQADVTKLELDAITNAANTRLRHAGGVAAAIARAGG 245
Query 1081 NAMQVESDDYIATNGPLKVGGSCVLSGHN-LAKHCLHVV-----GPNVNK---GEDIQLL 1131
+Q ES + P+ +G + + + A++ +H GP + L
Sbjct 246 PELQRESTE----KAPIGLGEAVETTAGDMPARYVIHAATMELGGPTSGEIITAATAATL 301
Query 1132 KSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT 1171
+ A E L G+ G + R+ V VR
Sbjct 302 RKADE--LGCRSLALVAFGTGVGGFPLDDAARLMVGAVRR 339
>sp|Q8BCR0|POLN_RUBVN Non-structural polyprotein p200 OS=Rubella
virus (strain RN-UK86) OX=376267 PE=3 SV=1
Length=2116
Score = 94.8 bits (234), Expect = 3e-17, Method: Composition-based stats.
Identities = 46/198 (23%), Positives = 68/198 (34%), Gaps = 18/198 (9%)
Query 987 TVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIV 1046
S + +EV + T + + Y + V+++ DI+
Sbjct 768 GDPDSPTSAEPADRARHAELEVVYEPSGPPTSTKADPDSDIVESYARAAGPVHLRVRDIM 827
Query 1047 EEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLS 1106
+ VVVNAAN L G GV GA+ A+ + P G +
Sbjct 828 DPPP--GCKVVVNAANEGLLAGSGVCGAIFANATAALAADC----RRLAPCPTGEAVATP 881
Query 1107 GHNLA-KHCLHVVGPN-----VNKGEDIQLLKSAYE------NFNQHEVLLAPLLSAGIF 1154
GH H +H V P E LL+ AY + + PLL AG++
Sbjct 882 GHGCGYTHIIHAVAPRRPRDPAALEEGEALLERAYRSIVALAAARRWACVACPLLGAGVY 941
Query 1155 GADPIHSLRVCVDTVRTN 1172
G SLR + RT
Sbjct 942 GWSAAESLRAALAATRTE 959
>sp|P13889|POLN_RUBVT Non-structural polyprotein p200 OS=Rubella
virus (strain Therien) OX=11045 PE=3 SV=5
Length=2116
Score = 93.6 bits (231), Expect = 7e-17, Method: Composition-based stats.
Identities = 46/183 (25%), Positives = 66/183 (36%), Gaps = 20/183 (11%)
Query 1004 TIVEVQPQLEMELTPVVQTIEVNS--FSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAA 1061
E++ E P + +S Y + V+++ DI++ VVVNAA
Sbjct 783 RDAELEVACEPSGPPTSTRADPDSDIVESYARAAGPVHLRVRDIMDPPP--GCKVVVNAA 840
Query 1062 NVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA-KHCLHVVGP 1120
N L G GV GA+ A+ P G + GH H +H V P
Sbjct 841 NEGLLAGSGVCGAIFANATAALAANC----RRLAPCPTGEAVATPGHGCGYTHIIHAVAP 896
Query 1121 N-----VNKGEDIQLLKSAYE------NFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTV 1169
E LL+ AY + + PLL AG++G SLR +
Sbjct 897 RRPRDPAALEEGEALLERAYRSIVALAAARRWACVACPLLGAGVYGWSAAESLRAALAAT 956
Query 1170 RTN 1172
RT
Sbjct 957 RTE 959
>sp|Q98TR3|RENT1_TAKRU Putative regulator of nonsense transcripts
1 OS=Takifugu rubripes OX=31033 GN=rent1 PE=3 SV=1
Length=1097
Score = 93.2 bits (230), Expect = 8e-17, Method: Composition-based stats.
Identities = 75/417 (18%), Positives = 137/417 (33%), Gaps = 100/417 (24%)
Query 5582 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAA 5637
+ D S V + V + S +QGPPGTGK+ L+ ++ A S+ A
Sbjct 450 LPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLSRQGNGP-VLVCAPSNIA 508
Query 5638 VDAL--------------CEKALKYLPIDKCSRIIPARARV------------------- 5664
VD L C K+ + + + +
Sbjct 509 VDQLTEKIDKTGLKVVRLCAKSREAIESPVSFLALHNQISNMDSMPELQKLQQLKDETGE 568
Query 5665 ------ECFDKFKVNST-----LEQYVFCT-VNA----LPETTADIVVFDEISMATNYDL 5708
+ + K + ++CT V A L + ++ DE + AT
Sbjct 569 LSSADEKRYRALKRTAERELLMNADVIWCTCVRAGDPRLAKMQFRSILIDESTQATE-PK 627
Query 5709 SVVNARLRAKHYVYIGDPAQLPAPRT-LLTKGTLEPEYFNSVCRLMKTIG-PDMFLGTCR 5766
+ L AK + ++ A + ++ K + S+ + +G + L
Sbjct 628 CIGPVELGAKQLIL----GEITASWSCVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQY 683
Query 5767 RCPAEIVDTVSALVYDNKLKAHK---------------DKSAQCFKMFYKGVITHDVS-- 5809
R + S + Y+ L+ F +G S
Sbjct 684 RMHPALSAFPSNIFYEGSLQNGVTAGDRIKKGFDFQWPQPEKPMFFYVTQGQEEIASSGT 743
Query 5810 SAINRPQIGVVREFLTR-----NPAWRKAVFISPYNSQNAVAS-----------KILGLP 5853
S +NR + V + TR + + I+PY Q + K+ +
Sbjct 744 SYLNRTEAANVEKITTRLLKAGAKPDQIGI-ITPYEGQRSYLVQYMQFSGSLHTKLYQVE 802
Query 5854 TQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
+VD+ QG E D++I + + + R NVA+TRAK G++ + + + L
Sbjct 803 IASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRAKYGVIIVGNPKAL 859
>sp|Q93RG0|ADPRH_TREMD Protein-ADP-ribose hydrolase OS=Treponema
medium OX=58231 PE=3 SV=1
Length=261
Score = 87.8 bits (216), Expect = 9e-17, Method: Composition-based stats.
Identities = 38/182 (21%), Positives = 67/182 (37%), Gaps = 32/182 (18%)
Query 1035 TDNVYIKNADIVEEAKKVKPTVVVNAANVYLKH-----GGGVAGALNKATNNAMQVESDD 1089
+ Y+ DI +K +VNAAN + + ++ ++
Sbjct 84 NGDWYVWRGDIT----TLKVDAIVNAANSGMTGCWQPCHACIDNCIHTFAGVQLRTVCAG 139
Query 1090 YIATNG-PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKG---EDIQLLKSAYENF------ 1138
+ G G + + NL K+ LH VGP ++ D LL ++Y +
Sbjct 140 IMQEQGHEEPTGTAKITPAFNLPCKYVLHTVGPIISGQLTDRDCTLLANSYTSCLNLAAE 199
Query 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT---------NVYLAVF---DKNLYDKL 1186
N + + +S G+F + + V TV + VF D+ LY+KL
Sbjct 200 NGVKSIAFCCISTGVFRFPAQKAAEIAVATVEDWKAKNNSAMKIVFNVFSEKDEALYNKL 259
Query 1187 VS 1188
+S
Sbjct 260 MS 261
>sp|Q306W8|POLN_EEEV8 Polyprotein P1234 OS=Eastern equine encephalitis
virus (strain PE-3.0815) OX=374597 PE=1 SV=3
Length=2474
Score = 92.8 bits (229), Expect = 1e-16, Method: Composition-based stats.
Identities = 52/268 (19%), Positives = 94/268 (35%), Gaps = 47/268 (18%)
Query 1039 YIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLK 1098
+ DI + +VNAAN + G GV GAL K A P+
Sbjct 1332 RVIRGDISKSTD----EAIVNAANNKGQPGAGVCGALYKKWPGAFDKV---------PIA 1378
Query 1099 VGGSCVLSGHNLAKHCLHVVGPNVNKGEDI---QLLKSAYENFNQ------HEVLLAPLL 1149
G + ++ + +H VGPN ++ ++ Q L Y + + + + PLL
Sbjct 1379 TGTAHLVKH---TPNIIHAVGPNFSRVSEVEGNQKLSEVYMDIAKIINRERYNKVSIPLL 1435
Query 1150 SAGIFGA------DPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKI 1203
S GI+ ++ L +DT +V + DK ++ + +S +++ +
Sbjct 1436 STGIYAGGKDRVMQSLNHLFTAMDTTDADVTIYCLDKQWEARIKDAIARKESVEELVEDD 1495
Query 1204 AEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGNL 1263
+ E V S+ R +V + LE T+F I +
Sbjct 1496 KPVDIELV---RVHPLSSLVGRPGYSTD----EGKVHSYLEGTRF--HQTAKDIAEIYAM 1546
Query 1264 HPDSATL-------VSDIDITFLKKDAP 1284
P+ V +T ++ P
Sbjct 1547 WPNKQEANEQICLYVLGESMTSIRSKCP 1574
Score = 56.6 bits (135), Expect = 1e-05, Method: Composition-based stats.
Identities = 58/297 (20%), Positives = 90/297 (30%), Gaps = 62/297 (21%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS G+ + R L A K + C+ II R
Sbjct 717 VYGVPGSGKS----GIIKSAVTKR------------DLVVSAKK----ENCTEIIKDVKR 756
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5723
+ D +N + + D + DE L + A ++ K V
Sbjct 757 MRGMDI-----AARTVDSVLLNGV-KHPVDTLYIDEAFACHAGTLLALIAIVKPKKVVLC 810
Query 5724 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5783
GDP Q + K E V RRC + VS L YD
Sbjct 811 GDPKQCGFFNMMCLKVHFNHEICTEVYHK----------SISRRCTKTVTAIVSTLFYDK 860
Query 5784 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5843
+++ I D +S + ++ LT W K + I Y +
Sbjct 861 RMRTVNP---------CSDKIIIDTTSTTKPQRDDII---LTCFRGWVKQLQID-YKNH- 906
Query 5844 AVASKILGLPTQTVDSSQGSEYDYVI---FTQTTETAHSCNVNRFNVAITRAKVGIL 5897
T +SQG V + ++ NV +TR + I+
Sbjct 907 ---------EIMTAAASQGLTRKGVYAVRYKVNENPLYAQTSEHVNVLLTRTEKRIV 954
>sp|Q6X2U2|POLN_RUBVC Non-structural polyprotein p200 OS=Rubella
virus (strain BRDII) OX=376263 PE=3 SV=1
Length=2116
Score = 92.8 bits (229), Expect = 1e-16, Method: Composition-based stats.
Identities = 40/180 (22%), Positives = 63/180 (35%), Gaps = 18/180 (10%)
Query 988 VGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVE 1047
S + EV + TP + + Y + V+++ +I++
Sbjct 769 DPASPISAEPADRARDAEPEVACEPGGPATPARADPDSDIVESYARAAGPVHLRVRNIMD 828
Query 1048 EAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSG 1107
VVVNAAN L G GV GA+ + ++ + P G + G
Sbjct 829 PPP--GCKVVVNAANEGLLAGSGVCGAIFASAAASLAEDC----RRLAPCPTGEAVATPG 882
Query 1108 HNLA-KHCLHVVGPN-----VNKGEDIQLLKSAYE------NFNQHEVLLAPLLSAGIFG 1155
H H +H V P + LL+ AY + + PLL AGI+G
Sbjct 883 HGCGYAHIIHAVAPRRPQDPAALEQSEALLERAYRSIVALAAARRWTCVACPLLGAGIYG 942
>sp|P27283|POLN_SINDO Polyprotein P1234 OS=Sindbis virus subtype
Ockelbo (strain Edsbyn 82-5) OX=31699 PE=3 SV=2
Length=2515
Score = 92.8 bits (229), Expect = 1e-16, Method: Composition-based stats.
Identities = 52/248 (21%), Positives = 97/248 (39%), Gaps = 34/248 (14%)
Query 1055 TVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHC 1114
VVNAAN + G GV A+ K N+ + + G + + H K
Sbjct 1364 EAVVNAANPLGRPGEGVCRAIYKRWPNSFTDSATE---------TGTAKLTVCH--GKKV 1412
Query 1115 LHVVGPNVNKG---EDIQLLKSAYEN----FNQH--EVLLAPLLSAGIFGADPIH----- 1160
+H VGP+ K E ++LL++AY N+H + + PLLS GI+ A
Sbjct 1413 IHAVGPDFRKHPEAEALKLLQNAYHAVADLVNEHNIKSVAIPLLSTGIYAAGKDRLEVSL 1472
Query 1161 -SLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESK 1219
L +D +V + DK +++ + E E K ++ ++ +I
Sbjct 1473 NCLTTALDRTDADVTIYCLDKKWKERIDAVL--QLKESVTELKDEDMEIDDELVWI-HPD 1529
Query 1220 PSVEQRK---QDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDI 1276
++ RK K+ + E T + K + E +L+ + + + + +
Sbjct 1530 SCLKGRKGFSTTKGKLYSYF-EGTKFHQAAKDMAEIKVLFPN-DQESNEQLCAYILGETM 1587
Query 1277 TFLKKDAP 1284
+++ P
Sbjct 1588 EAIREKCP 1595
Score = 45.4 bits (106), Expect = 0.025, Method: Composition-based stats.
Identities = 56/294 (19%), Positives = 87/294 (30%), Gaps = 60/294 (20%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS AI + +AR + T+ + L+ + S+ + +
Sbjct 724 VIGTPGSGKS--AIIKSTV--TARDLVTSGKKENCREIEADVLRLRGMQITSKTVDSVML 779
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRA-KHYVY 5722
C +++ DE L + A +R K V
Sbjct 780 NGCH----------------------KAVEVLYVDEAFACHAGALLALIAIVRPRKKVVL 817
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5782
GDP Q + K FN R + T F+ RRC + VS L YD
Sbjct 818 CGDPKQCGFFNMMQLKVH-----FNHPERDICTKTFYKFIS--RRCTQPVTAIVSTLHYD 870
Query 5783 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5842
K+K ++ G I G V++ P
Sbjct 871 GKMKTTNPCKKNI-EIDITGATKPKPGDIILTCFRGWVKQLQIDYP-------------- 915
Query 5843 NAVASKILGLPTQTVDSSQGSEYDYVIFT---QTTETAHSCNVNRFNVAITRAK 5893
G T +SQG V ++ NV +TR +
Sbjct 916 --------GHEVMTAAASQGLTRKGVYAVRQKVNENALYAITSEHVNVLLTRTE 961
>sp|Q9HCE1|MOV10_HUMAN Helicase MOV-10 OS=Homo sapiens OX=9606
GN=MOV10 PE=1 SV=2
Length=1003
Score = 92.4 bits (228), Expect = 1e-16, Method: Composition-based stats.
Identities = 82/400 (21%), Positives = 128/400 (32%), Gaps = 104/400 (26%)
Query 5604 LQGPPGTGKSHFAI----GLALYYPSARIVYTACSHAAVDALCEKALKYLPID------- 5652
+ GPPGTGK+ + + + P A I+ A S++ D LC++ +LP
Sbjct 522 IFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAP 581
Query 5653 -KCSRIIPARARVEC----------FDKFKVNSTLEQYVFCTVNA-------LPETTADI 5694
+ R++P + C F K + + A P
Sbjct 582 SRDIRMVPEDIKPCCNWDAKKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTH 641
Query 5695 VVFDEISMATNYDLSVVNARLR--------AKHYVYIGDPAQL-PAPRTLLTKGT-LEPE 5744
+ DE + V A L V GDP QL P R+ LT+ L
Sbjct 642 IFIDEAGHCMEPESLVAIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYS 701
Query 5745 ------YFNSVCRLMKTIGPDMFLGTC---RRCPAEIVDTVSALVYDNKLK---AHKDKS 5792
+NS+ + F+ R I+D + L Y+ +L+ D+
Sbjct 702 LLERLLTYNSLYKKGPDGYDPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRE 761
Query 5793 AQC---------FKMFYKGVITHD-----VSSAINRPQIGVVREFL------------TR 5826
C F + + GV+ D S N + V +L R
Sbjct 762 RFCRWAGLPRQGFPIIFHGVMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKAR 821
Query 5827 NPAWRKAVFISPYNSQNAVAS--------------KILGLPTQTVDSSQGSEYDYVIFTQ 5872
V ISPY Q I L +V+ QG E ++ +
Sbjct 822 LSPRSVGV-ISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILIST 880
Query 5873 TTETA------------HSCNVNRFNVAITRAKVGILCIM 5900
+ N RFNVA+TRAK ++ +
Sbjct 881 VRSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAKALLIIVG 920
>sp|P03317|POLN_SINDV Polyprotein P1234 OS=Sindbis virus OX=11034
PE=1 SV=2
Length=2513
Score = 92.4 bits (228), Expect = 2e-16, Method: Composition-based stats.
Identities = 51/248 (21%), Positives = 97/248 (39%), Gaps = 34/248 (14%)
Query 1055 TVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHC 1114
VVNAAN + G GV A+ K + + + G + + L K
Sbjct 1364 EAVVNAANPLGRPGEGVCRAIYKRWPTSFTDSATE---------TGTARMTVC--LGKKV 1412
Query 1115 LHVVGPNVNKG---EDIQLLKSAYEN----FNQH--EVLLAPLLSAGIFGADPIH----- 1160
+H VGP+ K E ++LL++AY N+H + + PLLS GI+ A
Sbjct 1413 IHAVGPDFRKHPEAEALKLLQNAYHAVADLVNEHNIKSVAIPLLSTGIYAAGKDRLEVSL 1472
Query 1161 -SLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESK 1219
L +D +V + DK +++ ++ E E K ++ ++ +I
Sbjct 1473 NCLTTALDRTDADVTIYCLDKKWKERIDAAL--QLKESVTELKDEDMEIDDELVWI-HPD 1529
Query 1220 PSVEQRK---QDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDI 1276
++ RK K+ + E T + K + E +L+ + + + + +
Sbjct 1530 SCLKGRKGFSTTKGKLYSYF-EGTKFHQAAKDMAEIKVLFPN-DQESNEQLCAYILGETM 1587
Query 1277 TFLKKDAP 1284
+++ P
Sbjct 1588 EAIREKCP 1595
Score = 43.9 bits (102), Expect = 0.093, Method: Composition-based stats.
Identities = 50/254 (20%), Positives = 81/254 (32%), Gaps = 62/254 (24%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS AI + +AR + T+ + L+ + S+ + +
Sbjct 724 VIGTPGSGKS--AIIKSTV--TARDLVTSGKKENCREIEADVLRLRGMQITSKTVDSVML 779
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRA-KHYVY 5722
C +++ DE L + A +R K V
Sbjct 780 NGCH----------------------KAVEVLYVDEAFACHAGALLALIAIVRPRKKVVL 817
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5782
GDP Q + K FN + + T ++ RRC + VS L YD
Sbjct 818 CGDPMQCGFFNMMQLKVH-----FNHPEKDICTKTFYKYIS--RRCTQPVTAIVSTLHYD 870
Query 5783 NKLKAHKDKSA-------------------QCFKMFYKG---------VITHDVSSAINR 5814
K+K CF+ + K V+T S + R
Sbjct 871 GKMKTTNPCKKNIEIDITGATKPKPGDIILTCFRGWVKQLQIDYPGHEVMTAAASQGLTR 930
Query 5815 PQIGVVREFLTRNP 5828
+ VR+ + NP
Sbjct 931 KGVYAVRQKVNENP 944
>sp|P40694|SMBP2_MOUSE DNA-binding protein SMUBP-2 OS=Mus musculus
OX=10090 GN=Ighmbp2 PE=1 SV=1
Length=993
Score = 91.3 bits (225), Expect = 3e-16, Method: Composition-based stats.
Identities = 58/266 (22%), Positives = 90/266 (34%), Gaps = 44/266 (17%)
Query 5687 LPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYF 5746
LPE D+VV DE + A + S L+A + GD QLP P T+ + L
Sbjct 363 LPEDYFDVVVVDECAQA--LEASCWIPLLKAPKCILAGDHRQLP-PTTVSHRAALA-GLS 418
Query 5747 NSVCRLMKT---IGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGV 5803
S+ + G L R I+ S +Y + +H + K
Sbjct 419 RSLMERLAEKHGAGVVRMLTVQYRMHQAIMCWASEAMYHGQFTSHPSVAGHLLKDLPGVT 478
Query 5804 ITHDV--------SSAINRPQIGVVREFLTRNPAWRKAV------------------FIS 5837
T + ++ ++ NP + V I+
Sbjct 479 DTEETRVPLLLIDTAGCGLLELEEEDSQSKGNPGEVRLVTLHIQALVDAGVQAGDIAVIA 538
Query 5838 PYNSQNAVASKILG-----LPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNV 5887
PYN Q + + L L ++VD QG E + V+ T + E R NV
Sbjct 539 PYNLQVDLLRQSLSNKHPELEIKSVDGFQGREKEAVLLTFVRSNRKGEVGFLAEDRRINV 598
Query 5888 AITRAKVGILCIMSDRDLYDKLQFTS 5913
A+TRA+ + I D + F
Sbjct 599 AVTRARRHVAVI-CDSHTVNNHAFLE 623
Score = 44.7 bits (104), Expect = 0.048, Method: Composition-based stats.
Identities = 16/51 (31%), Positives = 27/51 (53%), Gaps = 2/51 (4%)
Query 5596 VGMQKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEK 5644
+ ++ + + GPPGTGK+ I L +++ A S+ AVD L E+
Sbjct 203 LAQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNIAVDNLVER 253
>sp|Q86924|POLN_AURAV Polyprotein P1234 OS=Aura virus OX=44158
PE=3 SV=3
Length=2499
Score = 91.7 bits (226), Expect = 3e-16, Method: Composition-based stats.
Identities = 51/247 (21%), Positives = 89/247 (36%), Gaps = 32/247 (13%)
Query 1055 TVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHC 1114
VVNAAN K G GV A+ K + + + + V + + HN K
Sbjct 1362 EAVVNAANARGKPGDGVCRAIFKKWPKSFENATTE---------VETAVMKPCHN--KVV 1410
Query 1115 LHVVGPNVNKG---EDIQLLKSAY----ENFNQHEV--LLAPLLSAGIFGADPI------ 1159
+H VGP+ K E +LL++AY + N+ + + PLLS GI+ A
Sbjct 1411 IHAVGPDFRKYTLEEATKLLQNAYHDVAKIVNEKGISSVAIPLLSTGIYAAGADRLDLSL 1470
Query 1160 HSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESK 1219
L +D +V + DK ++ + E+ E K +I +E
Sbjct 1471 RCLFTALDRTDADVTIYCLDKKWEQRIADAIR--MREQVTELKDPDIEIDEGL-TRVHPD 1527
Query 1220 PSVEQRKQDDKKIKACVE--EVTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDIT 1277
++ + E T + K + E L+ D+ + +
Sbjct 1528 SCLKDHIGYSTQYGKLYSYFEGTKFHQTAKDIAEIRALFPDVQ-AANEQICLYTLGEPME 1586
Query 1278 FLKKDAP 1284
+++ P
Sbjct 1587 SIREKCP 1593
Score = 50.1 bits (118), Expect = 0.001, Method: Composition-based stats.
Identities = 49/254 (19%), Positives = 83/254 (33%), Gaps = 62/254 (24%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS AI + + + + T+ + K + +R + +
Sbjct 723 VIGTPGSGKS--AIIKSTV--TLKDLVTSGKKENCKEIENDVQKMRGMTIATRTVDSVL- 777
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH-YVY 5722
+ +K D++ DE L + A ++ + V
Sbjct 778 ---LNGWK------------------KAVDVLYVDEAFACHAGTLMALIAIVKPRRKVVL 816
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5782
GDP Q P + K FN+ R + T ++ RRC + VS L YD
Sbjct 817 CGDPKQWPFFNLMQLKV-----NFNNPERDLCTSTHYKYIS--RRCTQPVTAIVSTLHYD 869
Query 5783 NKLKAHKDKSA-------------------QCFKMFYK-------GVITHD--VSSAINR 5814
K++ CF+ + K G HD S + R
Sbjct 870 GKMRTTNPCKRAIEIDVNGSTKPKKGDIVLTCFRGWVKQGQIDYPGPGGHDRAASQGLTR 929
Query 5815 PQIGVVREFLTRNP 5828
+ VR+ + NP
Sbjct 930 RGVYAVRQKVNENP 943
>sp|Q6X2U4|POLN_RUBVB Non-structural polyprotein p200 OS=Rubella
virus (strain BRD1) OX=376262 PE=3 SV=1
Length=2116
Score = 91.3 bits (225), Expect = 4e-16, Method: Composition-based stats.
Identities = 40/182 (22%), Positives = 62/182 (34%), Gaps = 18/182 (10%)
Query 986 QTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADI 1045
S + EV + TP + + Y + V+++ +I
Sbjct 767 AGDPASPISAEPADRARDAEPEVACEPGGPATPTRADPDSDIVESYARAAGPVHLRVRNI 826
Query 1046 VEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVL 1105
++ VVVNAAN L G GV GA+ + + + P G +
Sbjct 827 MDPPP--GCKVVVNAANEGLLAGSGVCGAIFASAAATLAEDC----RRLAPCPTGEAVAT 880
Query 1106 SGHNLA-KHCLHVVGPN-----VNKGEDIQLLKSAYE------NFNQHEVLLAPLLSAGI 1153
GH H +H V P + LL+ AY + + PLL AGI
Sbjct 881 PGHGCGYTHIIHAVAPRRPQDPAALEQSEALLERAYRSVVALAAARRWACVACPLLGAGI 940
Query 1154 FG 1155
+G
Sbjct 941 YG 942
>sp|Q99IE5|POLN_RUBVV Non-structural polyprotein p200 OS=Rubella
virus (strain TO-336) OX=376264 PE=3 SV=1
Length=2116
Score = 90.5 bits (223), Expect = 6e-16, Method: Composition-based stats.
Identities = 42/169 (25%), Positives = 62/169 (37%), Gaps = 18/169 (11%)
Query 1005 IVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVY 1064
+EV + TP + + Y + V+++ DI++ VVVNAAN
Sbjct 786 ELEVAYEPSDPPTPTKADPDSDIVESYARAAGPVHLRVRDIMDPPP--GCKVVVNAANEG 843
Query 1065 LKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA-KHCLHVVGPN-- 1121
L G GV GA+ A+ + P G + GH H +H V P
Sbjct 844 LLAGSGVCGAIFANATAALAADC----RRLAPCPTGEAVATPGHGCGYTHIIHAVAPRRP 899
Query 1122 ---VNKGEDIQLLKSAYE------NFNQHEVLLAPLLSAGIFGADPIHS 1161
E LL+ AY + + PLL AG++G S
Sbjct 900 RDPAALEEGEALLERAYRSIVALAAARRWACVACPLLGAGVYGWSAAES 948
>sp|Q99IE7|POLN_RUBVO Non-structural polyprotein p200 OS=Rubella
virus (strain TO-336 vaccine) OX=376265 PE=3 SV=1
Length=2116
Score = 90.5 bits (223), Expect = 6e-16, Method: Composition-based stats.
Identities = 42/169 (25%), Positives = 62/169 (37%), Gaps = 18/169 (11%)
Query 1005 IVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVY 1064
+EV + TP + + Y + V+++ DI++ VVVNAAN
Sbjct 786 ELEVAYEPSDPPTPTKADPDSDIVESYARAAGPVHLRVRDIMDPPP--GCKVVVNAANEG 843
Query 1065 LKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA-KHCLHVVGPN-- 1121
L G GV GA+ A+ + P G + GH H +H V P
Sbjct 844 LLAGSGVCGAIFANATAALAADC----RRLAPCPTGEAVATPGHGCGYTHIIHAVAPRRP 899
Query 1122 ---VNKGEDIQLLKSAYE------NFNQHEVLLAPLLSAGIFGADPIHS 1161
E LL+ AY + + PLL AG++G S
Sbjct 900 RDPAALEEGEALLERAYRSIVALAAARRWACVACPLLGAGVYGWSAAES 948
>sp|Q8JUX6|POLN_CHIKS Polyprotein P1234 OS=Chikungunya virus (strain
S27-African prototype) OX=371094 PE=1 SV=1
Length=2474
Score = 90.1 bits (222), Expect = 8e-16, Method: Composition-based stats.
Identities = 47/230 (20%), Positives = 85/230 (37%), Gaps = 38/230 (17%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +K DI + VVNAAN G GV A+ K +
Sbjct 1333 CAPSYRVKRMDIAKN----DEECVVNAANPRGLPGDGVCKAVYKKWPESF---------K 1379
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENFNQH------EVL 1144
N VG + + +H VGPN + + + L +AY + +
Sbjct 1380 NSATPVGTAKTVMCGTYP--VIHAVGPNFSNYSESEGDRELAAAYREVAKEVTRLGVNSV 1437
Query 1145 LAPLLSAGIFGA------DPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS G++ ++ L +D+ +V + DK ++K +S ++M+++ +
Sbjct 1438 AIPLLSTGVYSGGKDRLTQSLNHLFTAMDSTDADVVIYCRDKE-WEKKISEAIQMRTQVE 1496
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKF 1248
+ + I + V S+ RK + + LE T+F
Sbjct 1497 LLDEHISIDCDVV---RVHPDSSLAGRKGYS----TTEGALYSYLEGTRF 1539
Score = 40.1 bits (92), Expect = 1.1, Method: Composition-based stats.
Identities = 42/254 (17%), Positives = 78/254 (31%), Gaps = 65/254 (26%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS L + + + T+ + ++ ++ +R + +
Sbjct 719 VFGVPGSGKSAIIKNLV----TRQDLVTSGKKENCQEITTDVMRQRGLEISARTVDSLLL 774
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH-YVY 5722
C D++ DE + L + A +R + V
Sbjct 775 NGCN----------------------RPVDVLYVDEAFACHSGTLLALIALVRPRQKVVL 812
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5782
GDP Q + K V RRC + VS+L Y+
Sbjct 813 CGDPKQCGFFNMMQMKVNYNHNICTQVYHK----------SISRRCTLPVTAIVSSLHYE 862
Query 5783 NKLKAHKDKSA-------------------QCFKMFYK----GVITHDVSSA-----INR 5814
K++ + + CF+ + K H+V +A + R
Sbjct 863 GKMRTTNEYNKPIVVDTTGSTKPDPGDLVLTCFRGWVKQLQIDYRGHEVMTAAASQGLTR 922
Query 5815 PQIGVVREFLTRNP 5828
+ VR+ + NP
Sbjct 923 KGVYAVRQKVNENP 936
>sp|Q0V8H6|MOV10_BOVIN Putative helicase MOV-10 OS=Bos taurus
OX=9913 GN=MOV10 PE=2 SV=1
Length=1003
Score = 89.7 bits (221), Expect = 8e-16, Method: Composition-based stats.
Identities = 82/399 (21%), Positives = 129/399 (32%), Gaps = 102/399 (26%)
Query 5604 LQGPPGTGKSHFAI----GLALYYPSARIVYTACSHAAVDALCEKALKYLPID------- 5652
+ GPPGTGK+ + + + P A I+ A S++ D LC++ +LP
Sbjct 522 IFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAP 581
Query 5653 -KCSRIIPARARVECFDKFKVNS----------TLEQYVFCTVNA-------LPETTADI 5694
+ ++P + C K + + A P
Sbjct 582 SRDIHLVPEDIKPCCNWDAKKGDFVFPSKKKLQEYRVLITTLITASRLVSAQFPIDHFTH 641
Query 5695 VVFDEISMATNYDLSVVNARLR--------AKHYVYIGDPAQL-PAPRTLLTKGT-LEPE 5744
+ DE A + V A L V GDP QL P R LT+ L
Sbjct 642 IFIDEAGHAMEPESLVAIAGLMEVKEADNPGGQLVLAGDPRQLGPVLRCPLTQKHGLGYS 701
Query 5745 ------YFNSVCRLMKTIGPDMFLGTC---RRCPAEIVDTVSALVYDNKLK---AHKDKS 5792
FN++ + F+ R I+D + L YD +L+ D+
Sbjct 702 LLERLLTFNALYKKGPDGYNPQFITKLLRNYRSHPTILDVPNRLYYDGELQACADVVDRE 761
Query 5793 AQC---------FKMFYKGVITHD-----VSSAINRPQIGVVREFLTR--NPAWRKAV-- 5834
C F + + GV+ D S N + V +L + P+ +K
Sbjct 762 RFCRWEGLPRQDFPIIFHGVMGKDEREGNSPSFFNPEEAATVTSYLKQLLAPSSKKGKAR 821
Query 5835 -------FISPYNSQNAVAS--------------KILGLPTQTVDSSQGSEYDYVIFTQT 5873
ISPY Q I L +V+ QG E ++ +
Sbjct 822 LSPRSVGVISPYRKQVEKIRYCITKLDKQLRGLDDIKDLKVGSVEEFQGQERSVILISTV 881
Query 5874 TETA------------HSCNVNRFNVAITRAKVGILCIM 5900
+ N RFNVA+TRAK ++ +
Sbjct 882 RSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAKALLIVVG 920
>sp|Q5XXP4|POLN_CHIK3 Polyprotein P1234 OS=Chikungunya virus (strain
37997) OX=371095 PE=1 SV=1
Length=2474
Score = 89.7 bits (221), Expect = 1e-15, Method: Composition-based stats.
Identities = 44/230 (19%), Positives = 85/230 (37%), Gaps = 38/230 (17%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +K DI + VVNAAN G GV A+ K +
Sbjct 1333 CAPSYRVKRMDIAKN----DEECVVNAANPRGLPGDGVCKAVYKKWPESF---------K 1379
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENFNQH------EVL 1144
N VG + + +H VGPN + + + L +AY + +
Sbjct 1380 NSATPVGTAKTVMCGTYP--VIHAVGPNFSNYSESEGDRELAAAYREVAKEVTRLGVNSV 1437
Query 1145 LAPLLSAGIFGA------DPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS G++ ++ L +D+ +V + DK ++K ++ ++M+++ +
Sbjct 1438 AIPLLSTGVYSGGKDRLTQSLNHLFTALDSTDADVVIYCRDKE-WEKKIAEAIQMRTQVE 1496
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKF 1248
+ + + + + S+ RK + + LE T+F
Sbjct 1497 LLDEHISVDCDII---RVHPDSSLAGRKGYS----TTEGSLYSYLEGTRF 1539
Score = 42.0 bits (97), Expect = 0.28, Method: Composition-based stats.
Identities = 42/254 (17%), Positives = 78/254 (31%), Gaps = 65/254 (26%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS L + + + T+ + ++ ++ +R + +
Sbjct 719 VFGVPGSGKSAIIKNLV----TRQDLVTSGKKENCQEISTDVMRQRNLEISARTVDSLLL 774
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH-YVY 5722
C D++ DE + L + A +R + V
Sbjct 775 NGCN----------------------RPVDVLYVDEAFACHSGTLLALIALVRPRQKVVL 812
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5782
GDP Q + K V RRC + VS+L Y+
Sbjct 813 CGDPKQCGFFNMMQMKVNYNHNICTQVYHK----------SISRRCTLPVTAIVSSLHYE 862
Query 5783 NKLKAHKDKSA-------------------QCFKMFYK----GVITHDVSSA-----INR 5814
K++ + + CF+ + K H+V +A + R
Sbjct 863 GKMRTTNEYNKPIVVDTTGSTKPDPGDLVLTCFRGWVKQLQIDYRGHEVMTAAASQGLTR 922
Query 5815 PQIGVVREFLTRNP 5828
+ VR+ + NP
Sbjct 923 KGVYAVRQKVNENP 936
>sp|Q09449|YQ12_CAEEL Uncharacterized ATP-dependent helicase C05C10.2
OS=Caenorhabditis elegans OX=6239 GN=C05C10.2 PE=3 SV=2
Length=1523
Score = 89.7 bits (221), Expect = 1e-15, Method: Composition-based stats.
Identities = 60/241 (25%), Positives = 94/241 (39%), Gaps = 31/241 (13%)
Query 5691 TADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTL-EPEYFNSV 5749
V DE S L + + IGD QLP +G L + N++
Sbjct 1174 DVCAVQIDEASQLAECTLLGLLKSFNNASFGLIGDIHQLPPYCEEGLEGKLKDFGIGNTM 1233
Query 5750 CRLMKT-IGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYK------- 5801
R +K + P L RC + + +S L YD L + + A+ M +
Sbjct 1234 ERAIKEKMFPVCTLRNVYRCHPKTTELLSELFYDGALVSGVSELARSDFMTKRDDFWPNP 1293
Query 5802 ----------GVITHDVSSAINRPQIGVVREFLT------RNPAWRKAV-FISPYNSQNA 5844
G T +S N + +V E + RNP + IS Y++Q +
Sbjct 1294 KFPMMFVNNTGASTKMGTSTSNSSEKSIVGEIVQNLINDPRNPVNPSDIGVISFYSAQTS 1353
Query 5845 VAS---KILGLPTQTVDSSQGSEYDYVIFTQTTE--TAHSCNVNRFNVAITRAKVGILCI 5899
+ + + G+ TVD+ QGSE + +I T E + NR NVA++RAK + I
Sbjct 1354 ILTEHLRGSGVKCGTVDAFQGSEKEIIIMCSTNERISDFMQLSNRLNVAMSRAKQVTIII 1413
Query 5900 M 5900
Sbjct 1414 G 1414
>sp|O40955|POLN_RUBVR Non-structural polyprotein p200 OS=Rubella
virus (strain RA27/3 vaccine) OX=11044 PE=1 SV=1
Length=2116
Score = 89.4 bits (220), Expect = 1e-15, Method: Composition-based stats.
Identities = 45/180 (25%), Positives = 65/180 (36%), Gaps = 18/180 (10%)
Query 1005 IVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVY 1064
+EV + T + + Y + V+++ DI++ VVVNAAN
Sbjct 786 ELEVAYEPSGPPTSTKADPDSDIVESYARAAGPVHLRVRDIMDPPP--GCKVVVNAANEG 843
Query 1065 LKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLA-KHCLHVVGPN-- 1121
L G GV GA+ A+ + P G + GH H +H V P
Sbjct 844 LLAGSGVCGAIFANATAALAADC----RRLAPCPTGEAVATPGHGCGYTHIIHAVAPRRP 899
Query 1122 ---VNKGEDIQLLKSAYENFNQHEVLLA------PLLSAGIFGADPIHSLRVCVDTVRTN 1172
E LL+ AY + PLL AG++G SLR + RT
Sbjct 900 RDPAALEEGEALLERAYRSIVALAAARRWARVACPLLGAGVYGWSAAESLRAALAATRTE 959
>sp|Q9BXT6|M10L1_HUMAN RNA helicase Mov10l1 OS=Homo sapiens OX=9606
GN=MOV10L1 PE=1 SV=1
Length=1211
Score = 89.0 bits (219), Expect = 1e-15, Method: Composition-based stats.
Identities = 77/426 (18%), Positives = 133/426 (31%), Gaps = 101/426 (24%)
Query 5606 GPPGTGKSHFAIGLAL----YYPSARIVYTACSHAAVDALCEKALKYLPIDKCS------ 5655
GPPGTGK+ I L P +RI+ A S++A D +C + + + +
Sbjct 770 GPPGTGKTVTIIEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNA 829
Query 5656 -----RIIPARARVECFDK---FKVNSTLEQYVFCTVNALPET------TADIVVFDEIS 5701
I+ + C D +K + C+ + L V DE
Sbjct 830 TCRFEEIVIDAVKPYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAG 889
Query 5702 MATNYDLSVVNARLR--AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM------ 5753
A+ + + + + V GDP QL + ++ + S +
Sbjct 890 QASEPECLIPLGLMSDISGQIVLAGDPMQLGP--VIKSRLAMAYGLNVSFLERLMSRPAY 947
Query 5754 ---------KTIGPDMF---LGTCRRCPAEIVDTVSALVYDNKLKAHKDKS--------- 5792
+ L R ++ S L Y +L+ D +
Sbjct 948 QRDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWE 1007
Query 5793 ---AQCFKMFYKGVITHD-----VSSAINRPQIGVVRE---FLTRNPAWRKAV----FIS 5837
+ F + + GV + S N + V L + + + + I+
Sbjct 1008 KLPKKGFPLIFHGVRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVIT 1067
Query 5838 PYNSQNAVASKIL------GLPTQTVDSSQGSEYDYVIFTQTTET-----------AHSC 5880
PY Q +L + +V+ QG EY +I +
Sbjct 1068 PYRKQVEKIRILLRNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLS 1127
Query 5881 NVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVI 5940
N RFNVAITR K ++ + + L F +L L+ G++ C
Sbjct 1128 NSKRFNVAITRPKALLIVLGNPHVLVRDPCFGAL---------LEYSITNGVYMGC---- 1174
Query 5941 TGLHPT 5946
L P
Sbjct 1175 -DLPPA 1179
>sp|O93327|H2AY_CHICK Core histone macro-H2A.1 OS=Gallus gallus
OX=9031 GN=MACROH2A1 PE=1 SV=4
Length=369
Score = 86.3 bits (212), Expect = 2e-15, Method: Composition-based stats.
Identities = 37/184 (20%), Positives = 64/184 (35%), Gaps = 22/184 (12%)
Query 1029 SGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESD 1088
+ L L + + ADI + VV+ N GG V L K
Sbjct 188 TKSLFLGQKLQVVQADI----ATIDSDAVVHPTNSDFYTGGEVGSTLEKKGGKEFVEAVI 243
Query 1089 DYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYENF------NQH 1141
+ NGPL + G+ V +GH L AK +H P + +LL+ +N +
Sbjct 244 ELRKKNGPLDIAGAVVSAGHGLPAKFVIHCNSPGWGSDKCEELLEKTVKNCLALADEKKL 303
Query 1142 EVLLAPLLSAGIFGADPIHSLRVCVDTVR-----------TNVYLAVFDKNLYDKLVSSF 1190
+ + P + +G G + ++ + + VY +FD V
Sbjct 304 KSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEM 363
Query 1191 LEMK 1194
++
Sbjct 364 AKLD 367
>sp|O75367|H2AY_HUMAN Core histone macro-H2A.1 OS=Homo sapiens
OX=9606 GN=MACROH2A1 PE=1 SV=5
Length=369
Score = 85.9 bits (211), Expect = 2e-15, Method: Composition-based stats.
Identities = 38/184 (21%), Positives = 65/184 (35%), Gaps = 22/184 (12%)
Query 1029 SGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESD 1088
+ L L + + ADI + VV+ N GG V L K
Sbjct 188 TKSLFLGQKLQVVQADI----ASIDSDAVVHPTNTDFYIGGEVGNTLEKKGGKEFVEAVL 243
Query 1089 DYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYEN------FNQH 1141
+ NGPL+V G+ V +GH L AK +H P + +LL+ +N +
Sbjct 244 ELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKL 303
Query 1142 EVLLAPLLSAGIFGADPIHSLRVCVDTVR-----------TNVYLAVFDKNLYDKLVSSF 1190
+ + P + +G G + ++ + + VY +FD V
Sbjct 304 KSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEM 363
Query 1191 LEMK 1194
++
Sbjct 364 AKLD 367
>sp|Q02874|H2AY_RAT Core histone macro-H2A.1 OS=Rattus norvegicus
OX=10116 GN=Macroh2a1 PE=1 SV=5
Length=368
Score = 85.9 bits (211), Expect = 2e-15, Method: Composition-based stats.
Identities = 38/184 (21%), Positives = 65/184 (35%), Gaps = 22/184 (12%)
Query 1029 SGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESD 1088
+ L L + + ADI + VV+ N GG V L K
Sbjct 187 TKSLFLGQKLQVVQADI----ASIDSDAVVHPTNADFYIGGEVGSTLEKKGGKEFVEAVL 242
Query 1089 DYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYEN------FNQH 1141
+ NGPL+V G+ V +GH L AK +H P + +LL+ +N +
Sbjct 243 ELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDRKL 302
Query 1142 EVLLAPLLSAGIFGADPIHSLRVCVDTVR-----------TNVYLAVFDKNLYDKLVSSF 1190
+ + P + +G G + ++ + + VY +FD V
Sbjct 303 KSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEM 362
Query 1191 LEMK 1194
++
Sbjct 363 AKLD 366
>sp|Q9QZQ8|H2AY_MOUSE Core histone macro-H2A.1 OS=Mus musculus
OX=10090 GN=Macroh2a1 PE=1 SV=4
Length=369
Score = 85.1 bits (209), Expect = 4e-15, Method: Composition-based stats.
Identities = 37/184 (20%), Positives = 65/184 (35%), Gaps = 22/184 (12%)
Query 1029 SGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESD 1088
+ L L + + ADI + VV+ N GG V L K
Sbjct 188 TKSLFLGQKLQVVQADI----ASIDSDAVVHPTNTDFYTGGEVGNTLEKKGGKEFVEAVL 243
Query 1089 DYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYEN------FNQH 1141
+ NGPL+V G+ + +GH L AK +H P + +LL+ +N +
Sbjct 244 ELRKKNGPLEVAGAAISAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDRKL 303
Query 1142 EVLLAPLLSAGIFGADPIHSLRVCVDTVR-----------TNVYLAVFDKNLYDKLVSSF 1190
+ + P + +G G + ++ + + VY +FD V
Sbjct 304 KSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFMLFDSESIGIYVQEM 363
Query 1191 LEMK 1194
++
Sbjct 364 AKLD 367
>sp|O90370|POLN_ONNVI Polyprotein P1234 OS=O'nyong-nyong virus
(strain Igbo Ora) OX=79899 PE=3 SV=1
Length=2513
Score = 87.8 bits (216), Expect = 4e-15, Method: Composition-based stats.
Identities = 45/230 (20%), Positives = 84/230 (37%), Gaps = 38/230 (17%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +K DI + + VVNAAN G GV A+ + +
Sbjct 1333 CAPSYRVKRMDIAKNTE----ECVVNAANPRGVPGDGVCKAVYRKWPESF---------R 1379
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENFNQH------EVL 1144
N VG + + +H VGPN + + + L SAY + +
Sbjct 1380 NSATPVGTAKTIMCGQYP--VIHAVGPNFSNYSEAEGDRELASAYREVAKEVSRLGVSSV 1437
Query 1145 LAPLLSAGIFGA------DPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS G++ ++ L +D+ +V + DK ++K ++ + ++S+ +
Sbjct 1438 AIPLLSTGVYSGGKDRLLQSLNHLFAAMDSTDADVVIYCRDKE-WEKKITEAISLRSQVE 1496
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKF 1248
+ + + V S+ RK + + LE T+F
Sbjct 1497 LLDDHISVDCDIV---RVHPDSSLAGRKGYS----TVEGALYSYLEGTRF 1539
Score = 39.3 bits (90), Expect = 1.9, Method: Composition-based stats.
Identities = 41/254 (16%), Positives = 78/254 (31%), Gaps = 65/254 (26%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS L + + + T+ + ++ ++ +R + +
Sbjct 719 VFGVPGSGKSAIIKNLV----TRQDLVTSGKKENCQEISNDVMRQRKLEISARTVDSLLL 774
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH-YVY 5722
C +++ DE + L + A +R + V
Sbjct 775 NGCN----------------------KPVEVLYVDEAFACHSGTLLALIAMVRPRQKVVL 812
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5782
GDP Q + K V RRC + VS+L Y+
Sbjct 813 CGDPKQCGFFNMMQMKVNYNHNICTQVYHK----------SISRRCTLPVTAIVSSLHYE 862
Query 5783 NKLKAHKDKSA-------------------QCFK-------MFYKGVI--THDVSSAINR 5814
+K++ + + CF+ + Y+G T S + R
Sbjct 863 SKMRTTNEYNQPIVVDTTGTTKPEPGDLVLTCFRGWVKQLQIDYRGNEVMTAAASQGLTR 922
Query 5815 PQIGVVREFLTRNP 5828
+ VR+ + NP
Sbjct 923 KGVYAVRQKVNENP 936
>sp|O90368|POLN_ONNVS Polyprotein P1234 OS=O'nyong-nyong virus
(strain SG650) OX=374989 PE=1 SV=1
Length=2513
Score = 87.0 bits (214), Expect = 7e-15, Method: Composition-based stats.
Identities = 44/230 (19%), Positives = 83/230 (36%), Gaps = 38/230 (17%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +K DI + + VVNAAN G GV A+ + +
Sbjct 1333 CAPSYRVKRMDIAKNTE----ECVVNAANPRGVPGDGVCKAVYRKWPESF---------R 1379
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENFNQH------EVL 1144
N VG + + +H VGPN + + + L S Y + +
Sbjct 1380 NSATPVGTAKTIMCGQYP--VIHAVGPNFSNYSEAEGDRELASVYREVAKEVSRLGVSSV 1437
Query 1145 LAPLLSAGIFGA------DPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS G++ ++ L +D+ +V + DK ++K ++ + ++S+ +
Sbjct 1438 AIPLLSTGVYSGGKDRLLQSLNHLFTAMDSTDADVVIYCRDKE-WEKKITEAISLRSQVE 1496
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKF 1248
+ + + V S+ RK + + LE T+F
Sbjct 1497 LLDDHISVDCDIV---RVHPDSSLAGRKGYS----TVEGALYSYLEGTRF 1539
Score = 39.3 bits (90), Expect = 1.8, Method: Composition-based stats.
Identities = 41/254 (16%), Positives = 78/254 (31%), Gaps = 65/254 (26%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS L + + + T+ + ++ ++ +R + +
Sbjct 719 VFGVPGSGKSAIIKNLV----TRQDLVTSGKKENCQEISNDVMRQRKLEISARTVDSLLL 774
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH-YVY 5722
C +++ DE + L + A +R + V
Sbjct 775 NGCN----------------------KPVEVLYVDEAFACHSGTLLALIAMVRPRQKVVL 812
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5782
GDP Q + K V RRC + VS+L Y+
Sbjct 813 CGDPKQCGFFNMMQMKVNYNHNICTQVYHK----------SISRRCTLPVTAIVSSLHYE 862
Query 5783 NKLKAHKDKSA-------------------QCFK-------MFYKGVI--THDVSSAINR 5814
+K++ + + CF+ + Y+G T S + R
Sbjct 863 SKMRTTNEYNQPIVVDTTGITKPEPGDLVLTCFRGWVKQLQIDYRGNEVMTAAASQGLTR 922
Query 5815 PQIGVVREFLTRNP 5828
+ VR+ + NP
Sbjct 923 KGVYAVRQKVNENP 936
>sp|P13886|POLN_ONNVG Polyprotein P1234 OS=O'nyong-nyong virus
(strain Gulu) OX=11028 PE=3 SV=2
Length=2514
Score = 87.0 bits (214), Expect = 8e-15, Method: Composition-based stats.
Identities = 59/367 (16%), Positives = 114/367 (31%), Gaps = 64/367 (17%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ +K DI + + VVNAAN G GV A+ + +
Sbjct 1333 CAPSYRVKRMDIAKNTE----ECVVNAANPRGVPGDGVCKAVYRKWPESF---------R 1379
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENFNQH------EVL 1144
N VG + + +H VGPN + + + L S Y + +
Sbjct 1380 NSATPVGTAKTIMCGQYP--VIHAVGPNFSNYSEAEGDRELASVYREVAKEVSRLGVSSV 1437
Query 1145 LAPLLSAGIFGA------DPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS G++ ++ L +D+ +V + DK ++K ++ + ++S+ +
Sbjct 1438 AIPLLSTGVYSGGKDRLLQSLNHLFAAMDSTDADVVIYCRDKE-WEKKITEAISLRSQVE 1496
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVE---------------EVTTTL 1243
+ + + V S+ RK A E+ T
Sbjct 1497 LLDDHISVDCDIV---RVHPDSSLAGRKGYSTVEGALYSYLEGTRFHQTAVDMAEIYTMW 1553
Query 1244 EETKFLTENLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVV------------ 1291
+ E + LY V D D +F K P + +
Sbjct 1554 PKQTEANEQVCLYALGESIESVRQKCPVDDADASFPPKTVPCLCRYAMTPERVARLRMNH 1613
Query 1292 QEGVLTAVVIPTKKAGGTTEMLAKALRKVPTDNYITTYPGQGL---NGYTVEEAKTVLKK 1348
++ P K K + + D+ + + ++ +T +
Sbjct 1614 TTSIIVCSSFPLPKYKIEGVQKVKCSKALLFDHNVPSRVSPRTYRPADEIIQTPQTPTEA 1673
Query 1349 CKSAFYI 1355
C+ A +
Sbjct 1674 CQDAQLV 1680
Score = 39.3 bits (90), Expect = 1.9, Method: Composition-based stats.
Identities = 41/254 (16%), Positives = 78/254 (31%), Gaps = 65/254 (26%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS L + + + T+ + ++ ++ +R + +
Sbjct 719 VFGVPGSGKSAIIKNLV----TRQDLVTSGKKENCQEISNDVMRQRKLEISARTVDSLLL 774
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH-YVY 5722
C +++ DE + L + A +R + V
Sbjct 775 NGCN----------------------KPVEVLYVDEAFACHSGTLLALIAMVRPRQKVVL 812
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5782
GDP Q + K V RRC + VS+L Y+
Sbjct 813 CGDPKQCGFFNMMQMKVNYNHNICTQVYHK----------SISRRCTLPVTAIVSSLHYE 862
Query 5783 NKLKAHKDKSA-------------------QCFK-------MFYKGVI--THDVSSAINR 5814
+K++ + + CF+ + Y+G T S + R
Sbjct 863 SKMRTTNEYNQPIVVDTTGITKPEPGDLVLTCFRGWVKQLQIDYRGNEVMTAAASQGLTR 922
Query 5815 PQIGVVREFLTRNP 5828
+ VR+ + NP
Sbjct 923 KGVYAVRQKVNENP 936
>sp|Q9J6K9|POLN_RUBVD Non-structural polyprotein p200 OS=Rubella
virus (strain Cendehill) OX=376266 PE=3 SV=2
Length=2116
Score = 86.3 bits (212), Expect = 1e-14, Method: Composition-based stats.
Identities = 42/186 (23%), Positives = 64/186 (34%), Gaps = 20/186 (11%)
Query 988 VGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVE 1047
V ++ + V +P T + + Y + V+++ DI++
Sbjct 771 VPPTPAEPADRARDAELEVAYEP--SGPPTSTKADPDSDIVESYARAAGPVHLRVRDIMD 828
Query 1048 EAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSG 1107
VVVNAAN L G GV GA+ A+ + P G + G
Sbjct 829 PPP--GCKVVVNAANEGLLAGSGVCGAIFANATAALAADC----RRLAPCPTGEAVATPG 882
Query 1108 HNLA-KHCLHVVGPN-----VNKGEDIQLLKSAYE------NFNQHEVLLAPLLSAGIFG 1155
H H +H V P E LL+ AY + + PLL AG++G
Sbjct 883 HGCGYTHIIHAVAPRRPRDPAALEEGEALLERAYRSIVALAAARRWAYVACPLLGAGVYG 942
Query 1156 ADPIHS 1161
S
Sbjct 943 WSAAES 948
>sp|Q5XGM5|GDAP2_XENLA Ganglioside-induced differentiation-associated
protein 2 OS=Xenopus laevis OX=8355 PE=2 SV=1
Length=496
Score = 84.0 bits (206), Expect = 2e-14, Method: Composition-based stats.
Identities = 47/295 (16%), Positives = 94/295 (32%), Gaps = 39/295 (13%)
Query 978 DWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDN 1037
D L S E P + P + F + +
Sbjct 2 DPLGARSCFVDADILPCW---ADVSNEEGEDVPDGGRKDVP--DGGSHSPFPYRKDINEK 56
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
V + D+ + T +VN +N L V+ ++ + + + E +
Sbjct 57 VILWKGDV----ALLNCTALVNTSNETLTDKNPVSDSIFRYSGPELLEE----MQKLKGC 108
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVN---KGEDIQLLKSAYENFNQH------EVLLAP 1147
+ G + + G NL A++ +H VGP + L S Y N Q +
Sbjct 109 RTGEAKLTKGFNLAARYIIHTVGPKYKTKYRTAAESSLYSCYRNVLQLAKEQGMASVGFC 168
Query 1148 LLSAGIFGADPIHSLRVCVDTVR----------TNVYLAVFDKNL--YDKLVSSFLEMKS 1195
+++ + + + TVR V AV ++ Y +L+ +
Sbjct 169 VITTQKRCYPLDDATHIALRTVRRFLEVHGQALEKVVFAVTEEEEGTYRRLLPLYF---- 224
Query 1196 EKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLT 1250
+ +E++ I ++ +P V +R+ + EE + K L+
Sbjct 225 PRSLEEEQRSILLLPQDIGNSDGEPVVPERQIRISEKPGVQEEDSEEEGLVKDLS 279
>sp|Q8QZ73|POLN_MAYAB Polyprotein P1234 OS=Mayaro virus (strain
Brazil) OX=374990 PE=1 SV=3
Length=2437
Score = 85.1 bits (209), Expect = 2e-14, Method: Composition-based stats.
Identities = 48/230 (21%), Positives = 76/230 (33%), Gaps = 38/230 (17%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+K ADI + VVNAAN + G GV A+ + A
Sbjct 1334 CAPAYAVKRADIATAIE----DAVVNAANHRGQVGDGVCRAVARKWPQAF---------R 1380
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYE---------NFNQHEVL 1144
N VG + + + +H VGPN N + + + N +
Sbjct 1381 NAATPVGTAKTVKCDE--TYIIHAVGPNFNNTSEAEGDRDLAAAYRAVAAEINRLSISSV 1438
Query 1145 LAPLLSAGIFGADPIH------SLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS GIF A L +DT V + DK K+ + + +
Sbjct 1439 AIPLLSTGIFSAGKDRVHQSLSHLLAAMDTTEARVTIYCRDKTWEQKIKT----VLQNRS 1494
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKF 1248
+ +++ + EV S+ R + + +E TKF
Sbjct 1495 ATELVSDELQFEVNLTRVHPDSSLVGRPGYS----TTDGTLYSYMEGTKF 1540
Score = 42.8 bits (99), Expect = 0.16, Method: Composition-based stats.
Identities = 47/259 (18%), Positives = 80/259 (31%), Gaps = 65/259 (25%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS L L K + C I+
Sbjct 720 VFGVPGSGKSGIIKSLVTR----------------GDLVASGKK----ENCQEIM---LD 756
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRA-KHYVY 5722
V+ + ++ T + +N + +T D++ DE L + A +R K V
Sbjct 757 VKRYRD--LDMTAKTVDSVLLNGVKQTV-DVLYVDEAFACHAGTLLALIATVRPRKKVVL 813
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5782
GDP Q + + V RRC I VS L Y+
Sbjct 814 CGDPKQCGFFNLMQLQVNFNHNICTEVDHK----------SISRRCTLPITAIVSTLHYE 863
Query 5783 NKLKAHKDKSA-------------------QCFKMFYK----GVITHDVSSA-----INR 5814
+++ + CF+ + K H+V +A + R
Sbjct 864 GRMRTTNPYNKPVIIDTTGQTKPNREDIVLTCFRGWVKQLQLDYRGHEVMTAAASQGLTR 923
Query 5815 PQIGVVREFLTRNPAWRKA 5833
+ VR + NP + ++
Sbjct 924 KGVYAVRMKVNENPLYAQS 942
>sp|Q2KIX2|GDAP2_BOVIN Ganglioside-induced differentiation-associated
protein 2 OS=Bos taurus OX=9913 GN=GDAP2 PE=2 SV=1
Length=497
Score = 83.6 bits (205), Expect = 3e-14, Method: Composition-based stats.
Identities = 47/270 (17%), Positives = 88/270 (33%), Gaps = 40/270 (15%)
Query 978 DWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDN 1037
D L SQ S N E+ + E T + F +
Sbjct 2 DPLGAPSQFVDVDTLPSWGNSCEDQLNASEIAAETYQEET------IRSPFLYNKDINGK 55
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
V + D+ + T +VN +N L V+ ++ ++ +
Sbjct 56 VVLWKGDV----ALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLRG----C 107
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVN---KGEDIQLLKSAYENFNQH------EVLLAP 1147
+ G + + G NL A+ +H VGP + L S Y N Q +
Sbjct 108 RTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFC 167
Query 1148 LLSAGIFGADPIHSLRVCVDTVR----------TNVYLAV--FDKNLYDKLVSSFLEMKS 1195
++++ G + + + TVR V AV ++ Y KL+ +
Sbjct 168 VINSAKRGYPLEDATHIALRTVRRFLEIHGETLEKVVFAVSELEEATYQKLLPLYF---- 223
Query 1196 EKQVEQKIAEIPKEEVKPFITESKPSVEQR 1225
+ ++++ +P E +P V +R
Sbjct 224 PRSLKEESRSLPCLPADIGNAEGEPVVPER 253
>sp|E9QAM5|HELZ2_MOUSE 3'-5' exoribonuclease HELZ2 OS=Mus musculus
OX=10090 GN=Helz2 PE=1 SV=1
Length=2947
Score = 84.7 bits (208), Expect = 3e-14, Method: Composition-based stats.
Identities = 60/299 (20%), Positives = 100/299 (33%), Gaps = 68/299 (23%)
Query 5695 VVFDEISMATNYD--LSVVNARLRAKHYVYIGDPAQLPA--PRTLLTKGTLEPEYFNSVC 5750
++ DE MAT + + +V + V +GD QL L ++ F
Sbjct 2654 ILIDEAGMATEPETLIPLVCFSKTVEKVVLLGDHKQLRPVVKSEQLQSLGMDRSLFERYH 2713
Query 5751 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD-------------KSAQCFK 5797
R + L T R +I S Y KLK D S
Sbjct 2714 R------DAIMLDTQYRMHKDICSFPSVEFYGGKLKTWSDLRRLPSILGHTGKPSCSVIF 2767
Query 5798 MFYKGVITH--------DVSSAINRPQIGVVREFLTRNPAWRKA-----VFISPYNSQNA 5844
+G + +S N ++ V + + R ++PYN+Q A
Sbjct 2768 GSVQGHEQKLLVSTEDGNENSRANPEEVTQVVRIIKQLTLDRTVDPKDIAVLTPYNAQAA 2827
Query 5845 VASK------ILGLPTQTVDSSQGSEYDYVIFT------------------QTTETAHSC 5880
S+ + G+ ++ SQGSE+ YVI +
Sbjct 2828 AISRGLMQRGVTGVTVTSITKSQGSEWRYVIVSTVRTCPRSDVDQRPTKSWLKKFLGFVV 2887
Query 5881 NVNRFNVAITRAKVGILCIMSDRDL-------YDKLQFTSLEIPRRNVATLQAENVTGL 5932
+ ++ NVAITRA+ LCI+ D L + L F + + ++ + + L
Sbjct 2888 DPHQVNVAITRAQEA-LCIIGDHLLLRCCPLWHRLLDFCEAQHSLVSAEKVRVQRKSAL 2945
>sp|Q5CZL1|GDAP2_XENTR Ganglioside-induced differentiation-associated
protein 2 OS=Xenopus tropicalis OX=8364 PE=2 SV=1
Length=496
Score = 82.4 bits (202), Expect = 6e-14, Method: Composition-based stats.
Identities = 43/247 (17%), Positives = 91/247 (37%), Gaps = 44/247 (18%)
Query 1026 NSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQV 1085
+ F + V + D+ + T +VN +N L V+ ++ + + +
Sbjct 45 SPFPYRNDINKKVILWRGDV----ALLSCTALVNTSNETLTDKNPVSDSIFRYSGPELSE 100
Query 1086 ESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVN---KGEDIQLLKSAYENFNQH 1141
E + + G + + G NL A++ +H VGP + L S Y N Q
Sbjct 101 E----MQKLKGCRTGEAKLTKGFNLAARYIIHTVGPKYKTKYRTAAESSLYSCYRNVLQL 156
Query 1142 ------EVLLAPLLSAGIFGADPIHSLRVCVDTVR----------TNVYLAVFDKNL--Y 1183
+ +++ P S + + TVR V AV ++ Y
Sbjct 157 AKEQGMASVGFCVIATQKRCYPPEDSTHIALRTVRRFLEAHGAALEKVVFAVTEQEEGTY 216
Query 1184 DKLVSSFLEMKSEKQVEQKIAEIP-------KEEVKPFITESKPSVEQRK---QDDKKIK 1233
+L+ + + +E++ IP E +P + E + + ++ DD + +
Sbjct 217 RRLLPLYF----PRSLEEEQRSIPFLPQDIGNAEGEPVVPERQIRISEKPGGQDDDSEEE 272
Query 1234 ACVEEVT 1240
V++++
Sbjct 273 GLVKDLS 279
>sp|P87515|POLN_BFV Polyprotein P1234 OS=Barmah forest virus OX=11020
PE=3 SV=3
Length=2411
Score = 84.0 bits (206), Expect = 6e-14, Method: Composition-based stats.
Identities = 46/205 (22%), Positives = 71/205 (35%), Gaps = 34/205 (17%)
Query 1039 YIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLK 1098
+K DI VVNAAN G GV GA+ + +A G +
Sbjct 1336 RVKRGDI----SNAPEDAVVNAANQQGVKGAGVCGAIYRKWPDAF-----------GDVA 1380
Query 1099 VGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENF------NQHEVLLAPLL 1149
+S K +H VGPN +K + + L SAY + + PLL
Sbjct 1381 TPTGTAVSKSVQDKLVIHAVGPNFSKCSEEEGDRDLASAYRAAAEIVMDKKITTVAVPLL 1440
Query 1150 SAGIFGA------DPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKI 1203
S GI+ ++ L D +V + DK K+ + S + V+ +
Sbjct 1441 STGIYAGGKNRVEQSLNHLFTAFDNTDADVTIYCMDKTWEKKIKEAIDHRTSVEMVQDDV 1500
Query 1204 AEIPKEEVKPFITESKPSVEQRKQD 1228
+ E + S+ RK
Sbjct 1501 ----QLEEELVRVHPLSSLAGRKGY 1521
Score = 43.9 bits (102), Expect = 0.075, Method: Composition-based stats.
Identities = 43/212 (20%), Positives = 69/212 (33%), Gaps = 37/212 (17%)
Query 5690 TTADIVVFDEISMATNYDLSVVNARLRAKH-YVYIGDPAQLPAPRTLLTKGTLEPEYFNS 5748
T +I+ DE L A +R K V GDP Q + K + +
Sbjct 777 HTPNILYIDEAFSCHAGTLLATIAIVRPKQKVVLCGDPKQCGFFNMMQLKVNYNHDICSE 836
Query 5749 VCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDV 5808
V RRC +I VS L Y ++++ + KG I D
Sbjct 837 VFHK----------SISRRCTQDITAIVSKLHYQDRMRTTNPR---------KGDIIIDT 877
Query 5809 SSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYV 5868
+ + ++ LT W K + Q+ G T +SQG V
Sbjct 878 TGTTKPAKTDLI---LTCFRGWVKQL------QQDYR-----GNEVMTAAASQGLTRASV 923
Query 5869 IFTQTT---ETAHSCNVNRFNVAITRAKVGIL 5897
+T ++ NV +TR + ++
Sbjct 924 YAVRTKVNENPLYAQTSEHVNVLLTRTENKLV 955
>sp|Q9YBE9|Y1648_AERPE Uncharacterized protein APE_1648.1 OS=Aeropyrum
pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 /
NBRC 100138 / K1) OX=272557 GN=APE_1648.1 PE=4 SV=2
Length=189
Score = 77.4 bits (189), Expect = 7e-14, Method: Composition-based stats.
Identities = 37/177 (21%), Positives = 69/177 (39%), Gaps = 27/177 (15%)
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
+ + D+ + V+ VVN AN + GGG AGAL +A + ++ E+ P+
Sbjct 11 LAVSMGDLTK----VRAEAVVNPANSLMIMGGGAAGALKRAGGSVIEEEAM----RKAPV 62
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYENF---------NQHEVLLAP 1147
VG + + SG +L A+ +H P + + L +A++ E + P
Sbjct 63 PVGEAVITSGGSLPARFVIHA--PTMEEPGMRIPLVNAFKASYAALRLASEAGIESVAMP 120
Query 1148 LLSAGIFG---ADPIHSLRVCVDTVRTN----VYLAVFDKNLYDKLVSSFLEMKSEK 1197
+ AG+ G A+ + +R + L + Y + E +
Sbjct 121 AMGAGVGGLSVAEVAREAAMAASILRGKWPRYIILVARGEEAYRGMEKGVREALGVE 177
>sp|Q9DBL2|GDAP2_MOUSE Ganglioside-induced differentiation-associated
protein 2 OS=Mus musculus OX=10090 GN=Gdap2 PE=1 SV=1
Length=498
Score = 82.0 bits (201), Expect = 8e-14, Method: Composition-based stats.
Identities = 44/270 (16%), Positives = 87/270 (32%), Gaps = 40/270 (15%)
Query 978 DWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDN 1037
D L SQ S + + + + F +
Sbjct 2 DPLGAPSQFVDVDTLLSWGDSYEDEVDCAD------STAEAFQEDASRSPFVYSRDVNGK 55
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
V + D+ + T +VN +N L V+ ++ ++ + +
Sbjct 56 VVLWKGDV----ALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKED----LQKLKGC 107
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVN---KGEDIQLLKSAYENFNQH------EVLLAP 1147
+ G + + G NL A+ +H VGP + L S Y N Q +
Sbjct 108 RTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFC 167
Query 1148 LLSAGIFGADPIHSLRVCVDTVR----------TNVYLAV--FDKNLYDKLVSSFLEMKS 1195
++++ G + + + TVR V AV ++ Y KL+ +
Sbjct 168 VINSAKRGYPLEDATHIALRTVRRFLEIHGENIEKVVFAVSELEEATYQKLLPLYF---- 223
Query 1196 EKQVEQKIAEIPKEEVKPFITESKPSVEQR 1225
+ ++++I +P E +P V +R
Sbjct 224 PRSLKEEIRSLPYLPADIGNAEGEPVVPER 253
>sp|Q9P2E3|ZNFX1_HUMAN NFX1-type zinc finger-containing protein
1 OS=Homo sapiens OX=9606 GN=ZNFX1 PE=1 SV=2
Length=1918
Score = 83.2 bits (204), Expect = 1e-13, Method: Composition-based stats.
Identities = 55/240 (23%), Positives = 92/240 (38%), Gaps = 32/240 (13%)
Query 5694 IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQL-PAPR--TLLTKGTLEPEYFNSVC 5750
IV+ +E + ++ +H + IGD QL P+ L LE F
Sbjct 1002 IVIVEEAAEVLE-AHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFE--- 1057
Query 5751 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN--------KLKAHKDKSAQCFKMFYK- 5801
RL+K P + L R EI ++ +Y + K + K S+ F + +
Sbjct 1058 RLVKVNIPFVRLNYQHRMCPEIARLLTPHIYQDLENHPSVLKYEKIKGVSSNLFFVEHNF 1117
Query 5802 -GVITHDVSSAINRPQIGVVRE----FLTRNPAWRKAVFISPYNSQNAVASKIL------ 5850
+ S N+ + V E FL + + ++ Y Q K++
Sbjct 1118 PEQEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKTFA 1177
Query 5851 GLPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
G+ VD QG E D ++ + Q + NR VA++RAK G+ CI + + L
Sbjct 1178 GVRVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQML 1237
>sp|P13887|POLN_RRVN Polyprotein P1234 OS=Ross river virus (strain
NB5092) OX=11031 PE=3 SV=2
Length=2480
Score = 82.8 bits (203), Expect = 2e-13, Method: Composition-based stats.
Identities = 42/210 (20%), Positives = 76/210 (36%), Gaps = 34/210 (16%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ ++ DI A+ VVNAAN G GV A+ + ++
Sbjct 1331 CAPSYRVRRTDISGHAE----EAVVNAANAKGTVGVGVCRAVARKWPDSF---------K 1377
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVL 1144
VG + ++ + + + +H VGPN + + + L +AY N + + +
Sbjct 1378 GAATPVGTAKLVQANGM--NVIHAVGPNFSTVTEAEGDRELAAAYRAVAGIINASNIKSV 1435
Query 1145 LAPLLSAGIFGA------DPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS G+F ++ L +DT +V + DK K+ E +
Sbjct 1436 AIPLLSTGVFSGGKDRVMQSLNHLFTAMDTTDADVVIYCRDKAWEKKI----QEAIDRRT 1491
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQD 1228
+ ++E E + RK
Sbjct 1492 AVELVSEDISLESDLIRVHPDSCLVGRKGY 1521
>sp|P13888|POLN_RRVT Polyprotein nsP1234 (Fragment) OS=Ross river
virus (strain T48) OX=11032 PE=1 SV=2
Length=1149
Score = 82.4 bits (202), Expect = 2e-13, Method: Composition-based stats.
Identities = 39/189 (21%), Positives = 69/189 (37%), Gaps = 30/189 (16%)
Query 1055 TVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHC 1114
VVNAAN G GV A+ + ++ VG + ++ + + +
Sbjct 17 EAVVNAANAKGTVGDGVCRAVARKWPDSF---------KGAATPVGTAKLVQANGM--NV 65
Query 1115 LHVVGPNVNKGEDIQ---LLKSAYE------NFNQHEVLLAPLLSAGIFGA------DPI 1159
+H VGPN + + + L +AY N + + + PLLS G+F +
Sbjct 66 IHAVGPNFSTVTEAEGDRELAAAYRAVAGIINASNIKSVAIPLLSTGVFSGGKDRVMQSL 125
Query 1160 HSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESK 1219
+ L +DT +V + DK K+ E + + ++E E
Sbjct 126 NHLFTAMDTTDADVVIYCRDKAWEKKI----QEAIDRRTAVELVSEDISLESDLIRVHPD 181
Query 1220 PSVEQRKQD 1228
+ RK
Sbjct 182 SCLVGRKGY 190
>sp|Q8R151|ZNFX1_MOUSE NFX1-type zinc finger-containing protein
1 OS=Mus musculus OX=10090 GN=Znfx1 PE=1 SV=3
Length=1909
Score = 82.0 bits (201), Expect = 2e-13, Method: Composition-based stats.
Identities = 55/247 (22%), Positives = 93/247 (38%), Gaps = 32/247 (13%)
Query 5687 LPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQL-PAPR--TLLTKGTLEP 5743
L + IV+ +E + ++ +H + IGD QL P+ L LE
Sbjct 988 LQQVEPRIVIVEEAAEVLE-AHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEV 1046
Query 5744 EYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN--------KLKAHKDKSAQC 5795
F RL+K P + L R EI ++ +Y + K + K S+
Sbjct 1047 SLFE---RLVKVNIPFVRLNYQHRMRPEIARLLTPHIYQDLENHPSVLKYEQIKGVSSNL 1103
Query 5796 FKMFYK--GVITHDVSSAINRPQIGVVREF----LTRNPAWRKAVFISPYNSQNAVASKI 5849
F + + + S N+ + V E L + + ++ Y Q K+
Sbjct 1104 FFVEHNFPEQEIQEGKSHQNQHEAHFVVELCQYLLCQEYLPSQITILTTYTGQLFCLRKL 1163
Query 5850 L------GLPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAITRAKVGILC 5898
+ G+ VD QG E D ++ + Q + NR VA++RAK G+ C
Sbjct 1164 MPVKTFAGIKVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQIPNRICVALSRAKKGMYC 1223
Query 5899 IMSDRDL 5905
I + + L
Sbjct 1224 IGNMQML 1230
>sp|Q86500|POLN_RUBVM Non-structural polyprotein p200 OS=Rubella
virus (strain M33) OX=11043 PE=1 SV=2
Length=2116
Score = 82.0 bits (201), Expect = 2e-13, Method: Composition-based stats.
Identities = 42/186 (23%), Positives = 64/186 (34%), Gaps = 20/186 (11%)
Query 988 VGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVE 1047
V ++ + V +P T + + Y + V+++ DI++
Sbjct 771 VPPTTAEPADRARHAELEVVYEP--SGPPTSTKADPDSDIVESYARAAGPVHLRVRDIMD 828
Query 1048 EAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSG 1107
VVVNAAN L G GV GA+ A+ + P +G + G
Sbjct 829 PPP--GCKVVVNAANEGLLAGSGVCGAIFANATAALAADC----RRLAPCPIGEAVATPG 882
Query 1108 HNLA-KHCLHVVGPN-----VNKGEDIQLLKSAYENFNQHEVLLA------PLLSAGIFG 1155
H H +H V P E LL+ AY + PLL AG++G
Sbjct 883 HGCGYTHIIHAVAPRRPRDPAALEEGEALLERAYRSIVALAAARRWARVACPLLGAGVYG 942
Query 1156 ADPIHS 1161
S
Sbjct 943 WSAAES 948
>sp|Q6QLN1|POLN_AHEV Non-structural polyprotein pORF1 OS=Avian
hepatitis E virus (isolate Chicken/California/Meng) OX=516993
GN=ORF1 PE=3 SV=1
Length=1531
Score = 81.7 bits (200), Expect = 3e-13, Method: Composition-based stats.
Identities = 49/266 (18%), Positives = 87/266 (33%), Gaps = 16/266 (6%)
Query 980 LDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVY 1039
+ E Q + + Q + T V + + G ++ +
Sbjct 563 VSAGPVPAPPGNPVIESVQGSGAGGPEVSESQPGLTPTREVTNMPLPPQRGQEEVLAVLP 622
Query 1040 IKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKV 1099
IV V +VN AN + GGG+ G ++ + + L
Sbjct 623 SGARVIVGNLLDVAADWLVNPANRDHQPGGGLCGMFHRRW-PHLWPVCGEVQ----DLPT 677
Query 1100 GGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQ-HEVLLAPLLSAGIFGADP 1158
G G +H GP+ D L+ Y +Q H + +PL+SAGI+ A
Sbjct 678 GPVIFQQG---PPKVIHAPGPDYRIKPDPDGLRRVYAVVHQAHGTVASPLISAGIYRAPA 734
Query 1159 IHSLRVCVDTVRTNVYLAVF---DKNLYDKLVSSFLEMKSEKQVEQKIAEI----PKEEV 1211
S T R L V +++ D +++ E V++ +A++ E
Sbjct 735 RESFEAWAATARDGDLLVVQRSMAQHIRDFVLNEGRHRPRELHVDRAMADMVNYGLATEP 794
Query 1212 KPFITESKPSVEQRKQDDKKIKACVE 1237
+P+ K + A V
Sbjct 795 EPYNELVKGVEVAPMTVKYALIAGVP 820
>sp|Q9NXN4|GDAP2_HUMAN Ganglioside-induced differentiation-associated
protein 2 OS=Homo sapiens OX=9606 GN=GDAP2 PE=1 SV=1
Length=497
Score = 80.1 bits (196), Expect = 3e-13, Method: Composition-based stats.
Identities = 46/270 (17%), Positives = 89/270 (33%), Gaps = 40/270 (15%)
Query 978 DWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDN 1037
D L SQ S + + ++ E T + F +
Sbjct 2 DPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDT------VRSPFLYNKDVNGK 55
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
V + D+ + T +VN +N L V+ ++ ++ + +
Sbjct 56 VVLWKGDV----ALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKED----LQKLKGC 107
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVN---KGEDIQLLKSAYENFNQH------EVLLAP 1147
+ G + + G NL A+ +H VGP + L S Y N Q +
Sbjct 108 RTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFC 167
Query 1148 LLSAGIFGADPIHSLRVCVDTVR----------TNVYLAVFD--KNLYDKLVSSFLEMKS 1195
++++ G + + + TVR V AV D + Y KL+ +
Sbjct 168 VINSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYF---- 223
Query 1196 EKQVEQKIAEIPKEEVKPFITESKPSVEQR 1225
+ ++++ +P E +P V +R
Sbjct 224 PRSLKEENRSLPYLPADIGNAEGEPVVPER 253
>sp|Q66H63|GDAP2_RAT Ganglioside-induced differentiation-associated-protein
2 OS=Rattus norvegicus OX=10116 GN=Gdap2 PE=2
SV=1
Length=497
Score = 80.1 bits (196), Expect = 3e-13, Method: Composition-based stats.
Identities = 44/270 (16%), Positives = 88/270 (33%), Gaps = 40/270 (15%)
Query 978 DWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDN 1037
D L SQ S + EV + + + F +
Sbjct 2 DPLGAPSQFVDVDTLVSWGDSY-----EDEVNSS-DSTAEAFQEDSNRSPFLYNRDINGK 55
Query 1038 VYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
V + D+ + T +VN +N L V+ ++ ++ + +
Sbjct 56 VVLWKGDV----ALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKED----LQKLKGC 107
Query 1098 KVGGSCVLSGHNL-AKHCLHVVGPNVN---KGEDIQLLKSAYENFNQH------EVLLAP 1147
+ G + + G NL A+ +H VGP + L S Y N Q +
Sbjct 108 RTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFC 167
Query 1148 LLSAGIFGADPIHSLRVCVDTVR----------TNVYLAV--FDKNLYDKLVSSFLEMKS 1195
++++ G + + + TVR V A+ ++ Y KL+ +
Sbjct 168 VINSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAISELEEATYQKLLPLYF---- 223
Query 1196 EKQVEQKIAEIPKEEVKPFITESKPSVEQR 1225
+ ++++ +P E +P V +R
Sbjct 224 PRSLKEESQSLPSLPADIGNAEGEPVVPER 253
>sp|Q8QL53|POLN_SLDV Polyprotein P1234 OS=Sleeping disease virus
OX=78540 PE=3 SV=1
Length=2593
Score = 81.3 bits (199), Expect = 5e-13, Method: Composition-based stats.
Identities = 40/179 (22%), Positives = 64/179 (36%), Gaps = 37/179 (21%)
Query 1029 SGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESD 1088
GY L N+ + V+VNAAN + G GV GAL A +A
Sbjct 1422 PGYRVLNKNII-----------TAEEEVLVNAANSNGRPGDGVCGALYGAFGDAF----- 1465
Query 1089 DYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGED---IQLLKSAYEN------FN 1139
NG + G + ++ G L +H G + + ++ + L++AY N
Sbjct 1466 ----PNGAIGAGNAVLVRG--LEATIIHAAGADFREVDEETGARQLRAAYRAAATLVTAN 1519
Query 1140 QHEVLLAPLLSAGIFGADPIH------SLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLE 1192
PLLS IF +L DT +V + N+ ++ +
Sbjct 1520 GITSAAIPLLSTHIFSNGRNRLEQSFGALVEAFDTTECDVTIYCLANNMAARIQQLIDD 1578
Score = 41.2 bits (95), Expect = 0.60, Method: Composition-based stats.
Identities = 42/206 (20%), Positives = 66/206 (32%), Gaps = 39/206 (19%)
Query 5691 TADIVVFDEISMATNYDLSVVNARLRAK-HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV 5749
D + DE + L + A +R V GDP Q+ L + E + V
Sbjct 809 AVDTLYVDEAYACHSGTLLALIAAVRPTGKVVLCGDPKQVGCVNQLQMRMHYNHEISDRV 868
Query 5750 CRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVS 5809
R RRC + VS L Y+ ++K K + D +
Sbjct 869 LRK----------NISRRCTHTLTAIVSNLNYEGRMKTTNP---------CKKPVLIDTT 909
Query 5810 SAINRPQIGVVREFLTRNPAWRKAV-FISPYNSQNAVASKILGLPTQTVDSSQG--SEYD 5866
+ + +V LT W K + + P+N T +SQG E
Sbjct 910 GSTKPDKEALV---LTCFRGWVKDLKILYPHN------------ELMTAAASQGLTREKV 954
Query 5867 YVIFT-QTTETAHSCNVNRFNVAITR 5891
Y + T+ + V +TR
Sbjct 955 YAVRCRVTSNPLYEPTSEHITVLLTR 980
>sp|Q99MV5|M10L1_MOUSE RNA helicase Mov10l1 OS=Mus musculus OX=10090
GN=Mov10l1 PE=1 SV=1
Length=1187
Score = 80.9 bits (198), Expect = 5e-13, Method: Composition-based stats.
Identities = 76/426 (18%), Positives = 135/426 (32%), Gaps = 103/426 (24%)
Query 5606 GPPGTGKSHFAIGLAL----YYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPAR 5661
GPPGTGK+ I L P +RI+ A S++A D +C + + + K + ++
Sbjct 772 GPPGTGKTVTIIEAVLQVHYALPDSRILVCAPSNSAADLVCLRLHESK-VPKPAAMVRVN 830
Query 5662 ARV------------ECFDK---FKVNSTLEQYVFCTVNALPETT------ADIVVFDEI 5700
A C D ++ + C+ L V DE
Sbjct 831 ATCRFEETIIDAIKPYCRDGEDIWRASRFRIIITTCSSAGLFYQIGVRVGYFTHVFVDEA 890
Query 5701 SMATNYDLSVVNARLR--AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM----- 5753
A+ + + + V GDP QL + ++ + S+ +
Sbjct 891 GQASEPECLIPLGLISDINGQIVLAGDPMQLGP--VIKSRLAMAYGLNVSMLERLMSRPA 948
Query 5754 ----------KTIGPDMF---LGTCRRCPAEIVDTVSALVYDNKLKAHKDKS-------- 5792
+ L R + ++ S L Y +L+ D
Sbjct 949 YLRDENAFGACGAYNPLLVTKLVKNYRSHSALLALPSRLFYHRELEVCADPKVVTSLLGW 1008
Query 5793 ----AQCFKMFYKGVITHD-----VSSAINRPQIGVVRE---FLTRNPAWRKAV----FI 5836
+ F + + GV ++ S + + V L R+ + + + I
Sbjct 1009 EKLPRKGFPLIFHGVRGNEAREGRSPSWFSPAEAVQVMRYCCLLARSVSSQVSSKDIGVI 1068
Query 5837 SPYNSQNAVASKIL------GLPTQTVDSSQGSEYDYVIFTQTTET-----------AHS 5879
+PY Q +L + +V+ QG EY ++ +
Sbjct 1069 TPYRKQVEKIKILLRNVDLTDIKVGSVEEFQGQEYLVIVISTVRSNEDRFEDDRYFLGFL 1128
Query 5880 CNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKV 5939
N RFNVAITR K ++ + + L F +L L+ G++ C
Sbjct 1129 SNSKRFNVAITRPKALLIILGNPHVLVRDPCFGAL---------LEYSVSNGVYTGC--- 1176
Query 5940 ITGLHP 5945
L P
Sbjct 1177 --DLPP 1180
>sp|Q8JJX1|POLN_SPDV Polyprotein P1234 OS=Salmon pancreas disease
virus OX=84589 PE=3 SV=1
Length=2601
Score = 80.5 bits (197), Expect = 6e-13, Method: Composition-based stats.
Identities = 36/149 (24%), Positives = 58/149 (39%), Gaps = 26/149 (17%)
Query 1053 KPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAK 1112
+ V+VNAAN + G GV GAL A +A NG + G + ++ G L
Sbjct 1436 EEEVLVNAANSNGRPGDGVCGALYGAFGDAF---------PNGAIGAGNAVLVRG--LEA 1484
Query 1113 HCLHVVGPNVNKGED---IQLLKSAYEN------FNQHEVLLAPLLSAGIFGADPIH--- 1160
+H G + + ++ + L++AY N PLLS IF
Sbjct 1485 TIIHAAGADFREVDEETGARQLRAAYRAAATLVTANGITSAAIPLLSTHIFSNGRNRLEQ 1544
Query 1161 ---SLRVCVDTVRTNVYLAVFDKNLYDKL 1186
+L DT +V + N+ ++
Sbjct 1545 SFSALVEAFDTTECDVTIYCLANNMAARI 1573
>sp|Q66HX8|GDAP2_DANRE Ganglioside-induced differentiation-associated
protein 2 OS=Danio rerio OX=7955 GN=gdap2 PE=2 SV=1
Length=504
Score = 79.0 bits (193), Expect = 8e-13, Method: Composition-based stats.
Identities = 40/242 (17%), Positives = 93/242 (38%), Gaps = 36/242 (15%)
Query 1026 NSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQV 1085
+ F+ + + + + N D+ + T +VN +N L ++ ++++ ++
Sbjct 55 SPFTFRQDINNKIVLFNGDV----ALLNCTAIVNTSNETLTDKNPISDSIHRHAGPELR- 109
Query 1086 ESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKG---EDIQLLKSAYENFNQH 1141
D+ + G + G + + G +L A+ +H VGP L S Y N Q
Sbjct 110 --DELLKLKG-CRTGEAKMTEGFDLAARFIIHTVGPKYKAKYRTAAESSLYSCYRNVLQL 166
Query 1142 E------VLLAPLLSAGIFGADPIHSLRVCVDTVR----------TNVYLAVFD--KNLY 1183
+ ++S + + + TVR + AV D + +Y
Sbjct 167 AKEHAMVSVGFCVISTVKRAYPVEDATHIALRTVRRFLENHGENIETLVFAVSDVEEPVY 226
Query 1184 DKLVSSFLEMKSEKQ---VEQKIAEIPKEEVKPFITESKPSVEQRK---QDDKKIKACVE 1237
KL+ + +++ + A+I E +P + E + + ++ +DD + +
Sbjct 227 RKLLPLYYPRSKQEERISLPLLPADIGNSEGEPVVPERQIRIAEKPVNLEDDPEDDSLDS 286
Query 1238 EV 1239
++
Sbjct 287 DL 288
>sp|E9P860|ZNFX1_CAEEL NFX1-type zinc finger-containing protein
1 homolog OS=Caenorhabditis elegans OX=6239 GN=znfx-1 PE=1
SV=1
Length=2443
Score = 80.5 bits (197), Expect = 8e-13, Method: Composition-based stats.
Identities = 56/250 (22%), Positives = 93/250 (37%), Gaps = 37/250 (15%)
Query 5686 ALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEY 5745
L + I++ +E + + +H V IGD QL P + + +
Sbjct 1455 TLEKVGPRILIVEEAAEVLEAHIISAMIST-VEHVVMIGDHKQLR-PNPAVHELGVAYGL 1512
Query 5746 FNSVCRLMKTIG-PDMFLGTCRRCPAEIVDTVSAL-VYDNKLKAHK-----DKSAQCFKM 5798
S+ + G P L R I D + L YDN A D +
Sbjct 1513 RISMFERLVERGLPFSQLRQQHRMNLTISDKIVKLSFYDNVTDAENVGLYPDVQGMATNL 1572
Query 5799 FYKGVITHDVS----SAINRPQIGV----VREFLTRNPAWRKAVFISPYNSQNAVASK-- 5848
F+ + + S S +N+ +I + V+ L +N V ++ Y++Q + +
Sbjct 1573 FFWSHTSMEESPDEVSWLNKHEISMTVALVKHLLKQNYTTNDIVVLATYSAQKNLMYREY 1632
Query 5849 --ILG-------LPTQTVDSSQGSEYDYVIFT---------QTTETAHSCNVNRFNVAIT 5890
+ G +P +TVDS QG E VI + + T NR VA+T
Sbjct 1633 ANVFGSTPDSNVIPVETVDSFQGKERKIVIVSLVRSHRGGRENTGIGFLAVANRICVALT 1692
Query 5891 RAKVGILCIM 5900
RA+ G+ I
Sbjct 1693 RAQHGMYIIG 1702
Score = 38.1 bits (87), Expect = 4.5, Method: Composition-based stats.
Identities = 16/64 (25%), Positives = 30/64 (47%), Gaps = 8/64 (13%)
Query 5598 MQKYSTLQGPPGTGKSHFAIGLALYYPSAR--------IVYTACSHAAVDALCEKALKYL 5649
+ S +QGPPGTGK+H + + R I+ +++ +D L E+ + +
Sbjct 1053 KYELSLIQGPPGTGKTHIGVQIVKTILQNRSYWKITEPILVVCFTNSGLDNLLERIYQMI 1112
Query 5650 PIDK 5653
D+
Sbjct 1113 ENDE 1116
>sp|Q5Y389|POLN_GETV Polyprotein P1234 OS=Getah virus OX=59300
PE=1 SV=3
Length=2467
Score = 80.1 bits (196), Expect = 1e-12, Method: Composition-based stats.
Identities = 46/230 (20%), Positives = 78/230 (34%), Gaps = 38/230 (17%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ ++ ADI VVNAAN GV A+ K ++
Sbjct 1332 CAPSYRVRRADISGH----SEEAVVNAANAKGTVSDGVCRAVAKKWPSSF---------K 1378
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENF------NQHEVL 1144
VG + ++ + +H VGPN + + + L +AY N + +
Sbjct 1379 GAATPVGTAKMIRADGM--TVIHAVGPNFSTVTEAEGDRELAAAYRAVASIISTNNIKSV 1436
Query 1145 LAPLLSAGIFGA------DPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS G F ++ L +D +V + DKN K+ E +
Sbjct 1437 AVPLLSTGTFSGGKDRVMQSLNHLFTALDATDADVVIYCRDKNWEKKI----QEAIDRRT 1492
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKF 1248
+ ++E E + R A ++ + LE T+F
Sbjct 1493 AIELVSEDVTLETDLVRVHPDSCLVGRNGYS----ATDGKLYSYLEGTRF 1538
>sp|Q9JGL0|POLN_SAGV Polyprotein P1234 OS=Sagiyama virus OX=59303
PE=3 SV=3
Length=2467
Score = 79.7 bits (195), Expect = 1e-12, Method: Composition-based stats.
Identities = 46/230 (20%), Positives = 78/230 (34%), Gaps = 38/230 (17%)
Query 1034 LTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIAT 1093
+ ++ ADI VVNAAN GV A+ K ++
Sbjct 1332 CAPSYRVRRADISGH----GEEAVVNAANAKGTVSDGVCRAVAKKWPSSF---------K 1378
Query 1094 NGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ---LLKSAYENF------NQHEVL 1144
VG + ++ + +H VGPN + + + L +AY N + +
Sbjct 1379 GAATPVGTAKMIRADGM--TVIHAVGPNFSTVTEAEGDRELAAAYRAVASIISTNNIKSV 1436
Query 1145 LAPLLSAGIFGA------DPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
PLLS G F ++ L +D +V + DKN K+ E +
Sbjct 1437 AVPLLSTGTFSGGKDRVMQSLNHLFTALDATDADVVIYCRDKNWEKKI----QEAIDRRT 1492
Query 1199 VEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKF 1248
+ ++E E + R A ++ + LE T+F
Sbjct 1493 AIELVSEDVTLETDLVRVHPDSCLVGRNGYS----ATDGKLYSYLEGTRF 1538
>sp|Q9BYK8|HELZ2_HUMAN 3'-5' exoribonuclease HELZ2 OS=Homo sapiens
OX=9606 GN=HELZ2 PE=1 SV=7
Length=2896
Score = 79.0 bits (193), Expect = 2e-12, Method: Composition-based stats.
Identities = 58/263 (22%), Positives = 91/263 (35%), Gaps = 58/263 (22%)
Query 5695 VVFDEISMATNYDLSVVNARL--RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRL 5752
++ DE MAT +++ +A+ V +GD QL + + S+
Sbjct 2604 ILVDEAGMATE-PETLIPLVQFPQAEKVVLLGDHKQLRP--VVKNERLQNLGLDRSLFER 2660
Query 5753 MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLK--------------AHKDKSAQCFKM 5798
L T R I S Y +KLK A K+ F
Sbjct 2661 YHE--DAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGH 2718
Query 5799 FYKGVITHDVS-------SAINRPQIGVVREF-----LTRNPAWRKAVFISPYNSQNAVA 5846
+ VS S N ++ V L R + ++PYN+Q +
Sbjct 2719 VQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEI 2778
Query 5847 SKIL------GLPTQTVDSSQGSEYDYVIFT------------------QTTETAHSCNV 5882
SK L G+ ++ SQGSE+ YV+ + +
Sbjct 2779 SKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDP 2838
Query 5883 NRFNVAITRAKVGILCIMSDRDL 5905
N+ NVA+TRA+ G LC++ D L
Sbjct 2839 NQVNVAVTRAQEG-LCLIGDHLL 2860
Score = 45.1 bits (105), Expect = 0.041, Method: Composition-based stats.
Identities = 53/381 (14%), Positives = 110/381 (29%), Gaps = 81/381 (21%)
Query 5603 TLQGPPGTGKSHFAIGLALYY------PSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5656
+ GP GTGK+ LA+ P +++ +++A D +
Sbjct 788 LIYGPFGTGKT---YTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPE 844
Query 5657 IIPARARVECFDKFKVNSTLEQY------------------------VFCTVNA----LP 5688
P R + + QY V T A +P
Sbjct 845 ATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARELRVP 904
Query 5689 ETTADIVVFDEISMATNYD-LSVVNARLRAKHYVYIGDPAQL-PAPRTLLTKGTLEPEYF 5746
++ DE + + L+ + V GD Q+ P ++ E
Sbjct 905 VGFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAAEHTLL 964
Query 5747 NSVCRLMKTIGPD------MFLGTCRRCPAEIVDTVSALVYDNKLKA-----HKDKSAQC 5795
+ + + + + RC IV +S Y K +
Sbjct 965 HRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRH 1024
Query 5796 FKMFY-----KGVITHDVSSAINRPQIGVVREFLT-RNPAW--------RKAVFISPYNS 5841
+ + + ++S +N +I V E + W ++ + + + +
Sbjct 1025 YPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGA 1084
Query 5842 QNAVASKIL---GLPTQTVDSSQ---GSEYDYVIFTQTTETA-----------HSCNVNR 5884
Q + + L L +V S + G ++ V+ + +
Sbjct 1085 QVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARV 1144
Query 5885 FNVAITRAKVGILCIMSDRDL 5905
N +TRA+ ++ + L
Sbjct 1145 LNTVLTRAQSQLVVVGDAVAL 1165
>sp|Q8B912|RPOA_PRRSB Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain HB-1) OX=300563
GN=rep PE=2 SV=3
Length=3961
Score = 77.0 bits (188), Expect = 8e-12, Method: Composition-based stats.
Identities = 94/560 (17%), Positives = 176/560 (31%), Gaps = 110/560 (20%)
Query 4837 DGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA-NQVIVNNLDKSAG 4895
+AA+ D Y L V+ +V KY + G C + AG
Sbjct 2738 CEDAALRDLSKYDLVTQGFV----LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAG 2793
Query 4896 FPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSIC 4955
N++ + S + D L A R T+T LK K + RT+ G +
Sbjct 2794 INGNRFPTKDI----QSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNF 2849
Query 4956 STMTNRQFHQKLLKSIAATR-GATVVIGTSKFYGGWHNMLKTVYSDVENPHL---MGWDY 5011
+ +R + + + + +G +KF +++ P L + D
Sbjct 2850 IALAHRAALSGVTQGFMKKAFNSPIALGKNKF------------KELQTPVLGRCLEADL 2897
Query 5012 PKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGG 5071
CDR+ P ++R A+ +L C+ H + N C ++++ K GG
Sbjct 2898 ASCDRSTPAIVRWFAANLLYEL---ACAEEHLPSYVLNCCH----DLLVTQSGAVTKRGG 2950
Query 5072 TSSGDATTAYANSVFN---ICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRD 5128
SSGD T+ +N++++ Q + + G+ ++++
Sbjct 2951 LSSGDPITSVSNTIYSLVIYAQHMVLSYFK----SGHPHGLLFLQDQLK----------- 2995
Query 5129 VDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSE 5188
+ + K +++ SDD V+ YA + + + L
Sbjct 2996 ---------FEDMLKVQPLIVYSDDLVL-----YAESPSMPNYHWWVEHLNLMLGFQTDP 3041
Query 5189 AKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMI 5248
K T F + G V P+ RIL A +
Sbjct 3042 KKTAITDSPT-----FLG---CRIINGRQLV----PNRDRILAALAYHMKASNVSEYYAS 3089
Query 5249 ERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYW 5308
++ +D+ ++ + + ++ Q RK D YS +
Sbjct 3090 A--AAILMDSCACLEYDPEWFEELVVGIAQCARK----------DGYS----------FP 3127
Query 5309 EPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYD----HVISTSHK 5364
P F+ +M+ + S CG C+ C D H H
Sbjct 3128 GPPFFLSMWEKLRSNHE--------GKKSRMCGYCMAPAPYATACGLDVCVYHTHFHQHC 3179
Query 5365 LVLSVNPYVCNAPGCDVTDV 5384
V+ + + C +
Sbjct 3180 PVIIWCGHPAGSGSCGECEP 3199
Score = 63.9 bits (154), Expect = 7e-08, Method: Composition-based stats.
Identities = 54/266 (20%), Positives = 90/266 (34%), Gaps = 45/266 (17%)
Query 6588 NARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAV------KTQFNYYKKVDGVVQQL 6641
+N + V L+P +A + ++G +V + K V G Q L
Sbjct 3624 TTQNNERWPDRLVASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVRGEAQVL 3683
Query 6642 PETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLH 6701
PET F+ R E R ++ E+A H GD + +GG H
Sbjct 3684 PETVFSTGRI--EVDCREYLDDREREVAES------------LPHAFIGDVKGTTVGGCH 3729
Query 6702 LLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTG-SSKCVCSVIDLLLDDFVEIIKS 6760
+ L F+P +S + + G ++K C++ D+ L D +
Sbjct 3730 HVTSKY---------LPRFLPKESVA---VVGVSSPGEAAKAFCTLTDVYLPDLEAYLHP 3777
Query 6761 QDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLL 6820
+ SK KV +D+ E+ M+W +T Y +L+ L +
Sbjct 3778 E---TQSKCWKVMLDFKEVRLMVW----KGKTAYFQLEGRH-----FTWYQLASYTSYIR 3825
Query 6821 EKCDLQNYGDSATLPKGIMMNVAKYT 6846
+ Y D P V T
Sbjct 3826 VPVNSTVYLDPCMGPALCNRRVVGST 3851
Score = 60.9 bits (146), Expect = 6e-07, Method: Composition-based stats.
Identities = 79/407 (19%), Positives = 134/407 (33%), Gaps = 90/407 (22%)
Query 5600 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5659
+ + GPPG GK+H+ + ++YT +H + + C +P
Sbjct 3287 RSRFIIGPPGAGKTHWLLQQV---QDGDVIYT-PTHQTMLDMIRALGT------CRFNVP 3336
Query 5660 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5719
A ++ F S +V + DE + + D+ + ++
Sbjct 3337 AGTTLQ----FPAPSRTGPWVRILAGGWCPGKNSFL--DEAAYCNHLDVLRLLSKTT--- 3387
Query 5720 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5779
+GD QL P F+S C + I P L T R I D +
Sbjct 3388 LTCLGDFKQL------------HPVGFDSHCYVF-DIMPQTQLKTIWRFGQNICDAIQPD 3434
Query 5780 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5839
Y +KL S +N ++ V + R ++PY
Sbjct 3435 -YRDKLV-----------------------SMVNTTRVTYVEK------PVRYGQVLTPY 3464
Query 5840 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCI 5899
+ + T+DSSQG+ +D V T T S N R VAITRA+ I
Sbjct 3465 HRDREDGA-------ITIDSSQGATFDVV--TLHLPTKDSLNRQRALVAITRARHAIFVY 3515
Query 5900 MSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK 5959
R L + N+A + E + L + + QA L KF+
Sbjct 3516 DPHRQLQSMFDL-PAKGTPVNLAVHRDEQLIVL----DRNNKEITVAQA---LGNGDKFR 3567
Query 5960 TEG---------LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
+C D+ G + ++ +GF + + + +
Sbjct 3568 ATDKRVVDSLRAICADLEGSSSPLP--KVAHNLGFYFSPDLTQFAKL 3612
>sp|Q6NYU2|HELZ_DANRE Probable helicase with zinc finger domain
OS=Danio rerio OX=7955 GN=helz PE=2 SV=1
Length=1860
Score = 76.6 bits (187), Expect = 9e-12, Method: Composition-based stats.
Identities = 71/394 (18%), Positives = 121/394 (31%), Gaps = 93/394 (24%)
Query 5602 STLQGPPGTGKSHF---AIGLALYYPSARIVYTACSHAAVDALCEKALKY------LPID 5652
+ GP GTGK+ A+ L P +R++ S++A D L K + P
Sbjct 657 VLIIGPYGTGKTFTLAQAVKHILKQPESRVLICTHSNSAAD-LYIKDYLHPYVEAGNPHA 715
Query 5653 KCSRI----------------------------IPARARVECFDKFKVNSTLEQYVFCTV 5684
+ R+ +P R VE V + QY+ C +
Sbjct 716 RPLRVYFRNRWVKTVHPLVQQYCLISGAHFTFQMPTRQDVERHRVVVVTLSTSQYL-CQL 774
Query 5685 NALPETTADIVVFDEISMATNYDLSV-VNARLRAKHYVYIGDPAQLPAPRT--LLTKGTL 5741
+ P I+ DE + A + + + +++ V GD QL + L
Sbjct 775 DLEPGIFTHIL-LDEAAQAMECETIMPLALAVKSTRVVLAGDHMQLSPFVYSEFARERNL 833
Query 5742 EPEYFNSVCRLMKTIGP-DMFLGTCRRCPAEIVDTVSALVYDNKLK------AHKDKSAQ 5794
+ + + P + L R I++ S L Y+ KL HKD
Sbjct 834 HVSLLDRLYEHYPSEYPCRILLCENYRSHEAIINYTSDLFYEGKLMASGKQPPHKDFYPL 893
Query 5795 CFKMFYKGVITHDVSSAI--NRPQIGVVREFLTRNPAWRKA---------VFISPYNSQN 5843
F + S+A N +V W + +SPY Q
Sbjct 894 TFFTARGEDVQEKNSTAYYNNAEVFEIVERVEEMRKKWPVSWGKLEEGSIGVVSPYADQV 953
Query 5844 A------VASKILGLPTQTVDSSQGSEYDYVIFT-----------QTT------------ 5874
++ + + V + QG ++ + + QT
Sbjct 954 FRIRAELRKKRMSEVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTAIKRKEQLVEDST 1013
Query 5875 ---ETAHSCNVNRFNVAITRAKVGILCIMSDRDL 5905
+ N N AITRA+ + + L
Sbjct 1014 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIAL 1047
>sp|A6YQT5|RPOA_PRRSV Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus OX=28344 PE=1 SV=2
Length=3931
Score = 76.3 bits (186), Expect = 1e-11, Method: Composition-based stats.
Identities = 96/560 (17%), Positives = 179/560 (32%), Gaps = 110/560 (20%)
Query 4837 DGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA-NQVIVNNLDKSAG 4895
+AA+ D Y + L V+ +V KY + G C + AG
Sbjct 2708 CEDAALRDLSKYDLSTQGFV----LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAG 2763
Query 4896 FPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSIC 4955
N++ + S + D L A R T+T LK K + RT+ G +
Sbjct 2764 INGNRFPTKDI----QSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNF 2819
Query 4956 STMTNRQFHQKLLKSIAATR-GATVVIGTSKFYGGWHNMLKTVYSDVENPHL---MGWDY 5011
+ +R + + + + +G +KF +++ P L + D
Sbjct 2820 IALAHRAALSGVTQGFMKKAFNSPIALGKNKF------------KELQAPVLGRCLEADL 2867
Query 5012 PKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGG 5071
CDR+ P ++R A+ +L C+ H + N C ++++ K GG
Sbjct 2868 ASCDRSTPAIVRWFAANLLYEL---ACAEEHLPSYVLNCCH----DLLVTQSGAVTKRGG 2920
Query 5072 TSSGDATTAYANSVFN---ICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRD 5128
SSGD T+ +N++++ Q + + G+ ++++
Sbjct 2921 LSSGDPITSVSNTIYSLVIYAQHMVLSYFK----SGHPHGLLFLQDQLK----------- 2965
Query 5129 VDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSE 5188
+ + K +++ SDD V+ YA + + + L
Sbjct 2966 ---------FEDMLKVQPLIVYSDDLVL-----YAESPSMPNYHWWVEHLNLMLGFQTDP 3011
Query 5189 AKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMI 5248
K T +T P S + G V P+ RIL A +
Sbjct 3012 KK----TTITDSP----SFLGCRIINGRQLV----PNRDRILAALAYHMKASNVSEYYAS 3059
Query 5249 ERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYW 5308
++ +D+ ++ + + ++ Q RK D YS +
Sbjct 3060 A--AAILMDSCACLEYDPEWFEELVVGIAQCARK----------DGYS----------FP 3097
Query 5309 EPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYD----HVISTSHK 5364
P F+ +M+ + S CG C C D H H
Sbjct 3098 GPPFFLSMWEKLRSNHE--------GKKSRMCGYCGAPAPYATACGLDVCVYHTHFHQHC 3149
Query 5365 LVLSVNPYVCNAPGCDVTDV 5384
V+ + + C +
Sbjct 3150 PVIIWCGHPAGSGSCSECEP 3169
Score = 64.7 bits (156), Expect = 4e-08, Method: Composition-based stats.
Identities = 54/266 (20%), Positives = 91/266 (34%), Gaps = 45/266 (17%)
Query 6588 NARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAV------KTQFNYYKKVDGVVQQL 6641
+N + V L+P +A + ++G +V + K V G Q L
Sbjct 3594 TTQNNERWPDRLVASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVRGEAQVL 3653
Query 6642 PETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLH 6701
PET F+ R E R ++ E+A H GD + +GG H
Sbjct 3654 PETVFSTGRI--EVDCREYLDDREREVAES------------LPHAFIGDVKGTTVGGCH 3699
Query 6702 LLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTG-SSKCVCSVIDLLLDDFVEIIKS 6760
+ L F+P +S + + G ++K VC++ D+ L D +
Sbjct 3700 HVTSKY---------LPRFLPKESVA---VVGVSSPGKAAKAVCTLTDVYLPDLEAYLHP 3747
Query 6761 QDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLL 6820
+ S+ KV +D+ E+ M+W +T Y +L+ L +
Sbjct 3748 E---TQSRCWKVMLDFKEVRLMVW----KDKTAYFQLEGRH-----FTWYQLASYASYIR 3795
Query 6821 EKCDLQNYGDSATLPKGIMMNVAKYT 6846
+ Y D P V T
Sbjct 3796 VPVNSTVYLDPCMGPALCNRRVVGST 3821
Score = 61.2 bits (147), Expect = 5e-07, Method: Composition-based stats.
Identities = 79/407 (19%), Positives = 134/407 (33%), Gaps = 90/407 (22%)
Query 5600 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5659
+ + GPPG GK+H+ + ++YT +H + + C +P
Sbjct 3257 RSRFIIGPPGAGKTHWLLQQV---QDGDVIYT-PTHQTMLDMIRALGT------CRFNVP 3306
Query 5660 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5719
A ++ F S +V + DE + + D+ + ++
Sbjct 3307 AGTTLQ----FPAPSRTGPWVRILAGGWCPGKNSFL--DEAAYCNHLDVLRLLSKTT--- 3357
Query 5720 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5779
+GD QL P F+S C + I P L T R I D +
Sbjct 3358 LTCLGDFKQL------------HPVGFDSHCYVF-DIMPQTQLKTIWRFGQNICDAIQPD 3404
Query 5780 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5839
Y +KL S +N ++ V + R ++PY
Sbjct 3405 -YRDKL-----------------------MSMVNTTRVTYVEK------PVRYGQVLTPY 3434
Query 5840 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCI 5899
+ + T+DSSQG+ +D V T T S N R VAITRA+ I
Sbjct 3435 HRDREDGA-------ITIDSSQGATFDVV--TLHLPTKDSLNRQRALVAITRARHAIFVY 3485
Query 5900 MSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK 5959
R L + N+A + E + L + + QA L KF+
Sbjct 3486 DPHRQLQSMFDL-PAKGTPVNLAVHRDEQLIVL----DRNNREITVAQA---LGNGDKFR 3537
Query 5960 TEG---------LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
+C D+ G + ++ +GF + + + +
Sbjct 3538 ATDKRVVDSLRAICADLEGSSSPLP--KVAHNLGFYFSPDLTQFAKL 3582
>sp|Q9WJB2|RPOA_PRRSR Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain VR-2332) OX=300559
GN=rep PE=1 SV=2
Length=3960
Score = 75.5 bits (184), Expect = 3e-11, Method: Composition-based stats.
Identities = 78/449 (17%), Positives = 152/449 (34%), Gaps = 88/449 (20%)
Query 4837 DGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA-NQVIVNNLDKSAG 4895
+AA+ D Y + L V+ +V KY + G C + AG
Sbjct 2737 CEDAALKDLSKYDLSTQGFV----LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAG 2792
Query 4896 FPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVS-I 4954
N++ + S + D L A R T+T LK K + RT+ G +
Sbjct 2793 INGNRFPTKDI----QSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNF 2848
Query 4955 CSTMTNRQFHQKLLKSIAA-----TRGATVVIGTSKFYGGWHNMLKTVYSDVENPHL--- 5006
+ H+ +L + + + +G +KF +++ P L
Sbjct 2849 IA-----LAHRAVLSGVTQGFMKKAFNSPIALGKNKF------------KELQTPVLGRC 2891
Query 5007 MGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLY 5066
+ D CDR+ P ++R A+ +L C+ H + N C ++++
Sbjct 2892 LEADLASCDRSTPAIVRWFAANLLYEL---ACAEEHLPSYVLNCCH----DLLVTQSGAV 2944
Query 5067 VKPGGTSSGDATTAYANSVFN---ICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECL 5123
K GG SSGD T+ +N++++ Q + + G+ ++++
Sbjct 2945 TKRGGLSSGDPITSVSNTIYSLVIYAQHMVLSYFK----SGHPHGLLFLQDQLK------ 2994
Query 5124 YRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNN 5183
+ + K +++ SDD V+ YA + + + L
Sbjct 2995 --------------FEDMLKVQPLIVYSDDLVL-----YAESPTMPNYHWWVEHLNLMLG 3035
Query 5184 VFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTD 5243
K T +T P S + G V P+ RIL A +
Sbjct 3036 FQTDPKK----TAITDSP----SFLGCRIINGRQLV----PNRDRILAALAYHMKASNVS 3083
Query 5244 GTLMIERFVSLAIDAYPLTKHPNQEYADV 5272
++ +D+ ++ + + ++
Sbjct 3084 EYYASA--AAILMDSCACLEYDPEWFEEL 3110
Score = 60.1 bits (144), Expect = 1e-06, Method: Composition-based stats.
Identities = 77/403 (19%), Positives = 131/403 (33%), Gaps = 82/403 (20%)
Query 5600 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5659
+ + GPPG GK+++ + ++YT +H + + C +P
Sbjct 3286 RSRFIIGPPGAGKTYWLLQQV---QDGDVIYT-PTHQTMLDMIRALGT------CRFNVP 3335
Query 5660 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5719
A ++ F V S +V + DE + + D+ + ++
Sbjct 3336 AGTTLQ----FPVPSRTGPWVRILAGGWCPGKNSFL--DEAAYCNHLDVLRLLSKTT--- 3386
Query 5720 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5779
+GD QL P F+S C + I P L T R I D +
Sbjct 3387 LTCLGDFKQL------------HPVGFDSHCYVF-DIMPQTQLKTIWRFGQNICDAIQPD 3433
Query 5780 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5839
Y +KL S +N ++ V + R ++PY
Sbjct 3434 -YRDKL-----------------------MSMVNTTRVTYVEK------PVRYGQVLTPY 3463
Query 5840 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCI 5899
+ T+DSSQG+ +D V T T S N R VAITRA+ I
Sbjct 3464 HRDRED-------DAITIDSSQGATFDVV--TLHLPTKDSLNRQRALVAITRARHAIFVY 3514
Query 5900 MSDRDLYDKLQF----TSLEIPRRNVATLQAENVTGLFKDCS-KVITGLHPTQAPTHLSV 5954
R L T + + L + K+C+ G T V
Sbjct 3515 DPHRQLQGLFDLPAKGTPVNLAVHCDGQLIVLDRNN--KECTVAQALGNGDKFRATDKRV 3572
Query 5955 DTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
+ +C D+ G + ++ +GF + + + +
Sbjct 3573 VDSLRA--ICADLEGSSSPLP--KVAHNLGFYFSPDLTQFAKL 3611
Score = 59.7 bits (143), Expect = 1e-06, Method: Composition-based stats.
Identities = 46/259 (18%), Positives = 87/259 (34%), Gaps = 41/259 (16%)
Query 6590 RNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQS 6649
+ ++ + + + + +G + K V G Q LPET F+
Sbjct 3631 PDRLVASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVKGGAQVLPETVFSTG 3690
Query 6650 RNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYA-FEHIVYGDFSHSQLGGLHLLIGLAK 6708
R +E+ E+++ + E A H GD + +GG H +
Sbjct 3691 R---------------IEVDCREYLDDREREVAASLPHGFIGDVKGTTVGGCHHVTSRY- 3734
Query 6709 RFKESPFELEDFIPMDSTVKNYFITDAQTG-SSKCVCSVIDLLLDDFVEIIKSQDLSVVS 6767
L +P +S + + G ++K +C++ D+ L D + + S
Sbjct 3735 --------LPRVLPKESVA---VVGVSSPGKAAKALCTLTDVYLPDLEAYLHPE---TQS 3780
Query 6768 KVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQN 6827
K K+ +D+ E+ M+W +T Y +L+ L + +
Sbjct 3781 KCWKMMLDFKEVRLMVW----KDKTAYFQLEGRY-----FTWYQLASYASYIRVPVNSTV 3831
Query 6828 YGDSATLPKGIMMNVAKYT 6846
Y D P V T
Sbjct 3832 YLDPCMGPALCNRRVVGST 3850
>sp|Q9YN02|RPOA_PRRS1 Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain 16244B) OX=300561
GN=rep PE=1 SV=3
Length=3961
Score = 74.7 bits (182), Expect = 4e-11, Method: Composition-based stats.
Identities = 78/441 (18%), Positives = 150/441 (34%), Gaps = 72/441 (16%)
Query 4837 DGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA-NQVIVNNLDKSAG 4895
+AA+ D Y + L V+ +V KY + G C + AG
Sbjct 2738 CEDAALKDLSKYDLSTQGFV----LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAG 2793
Query 4896 FPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSIC 4955
N++ + S + D L A R T+T LK K + RT+ G +
Sbjct 2794 INGNRFPTKDI----QSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNF 2849
Query 4956 STMTNRQFHQKLLKSIAATR-GATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKC 5014
+ +R + + + + +G +KF K + + V L D C
Sbjct 2850 IALAHRAALSGVTQGFMKKAFNSPIALGKNKF--------KELQTSVLGRCL-EADLASC 2900
Query 5015 DRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSS 5074
DR+ P ++R A+ +L C+ H + N C ++++ K GG SS
Sbjct 2901 DRSTPAIVRWFAANLLYEL---ACAEEHLPSYVLNCCH----DLLVTQSGAVTKRGGLSS 2953
Query 5075 GDATTAYANSVFN---ICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDT 5131
GD T+ +N++++ Q + + G+ ++++
Sbjct 2954 GDPITSVSNTIYSLVIYAQHMVLSYFK----SGHPHGLLFLQDQLK-------------- 2995
Query 5132 DFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKC 5191
+ + K +++ SDD V+ YA + + + L K
Sbjct 2996 ------FEDMLKVQPLIVYSDDLVL-----YAESPTMPNYHWWVEHLNLMLGFQTDPKK- 3043
Query 5192 WTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERF 5251
T +T P S + G V P+ RIL A +
Sbjct 3044 ---TAITDSP----SFLGCRIINGRQLV----PNRDRILAALAYHMKASNVSEYYASA-- 3090
Query 5252 VSLAIDAYPLTKHPNQEYADV 5272
++ +D+ ++ + + ++
Sbjct 3091 AAILMDSCACLEYDPEWFEEL 3111
Score = 61.2 bits (147), Expect = 5e-07, Method: Composition-based stats.
Identities = 46/259 (18%), Positives = 87/259 (34%), Gaps = 41/259 (16%)
Query 6590 RNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQS 6649
+ ++ + + + + +G + K V G Q LPET F+
Sbjct 3632 PDRLVASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVKGEAQLLPETVFSTG 3691
Query 6650 RNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYA-FEHIVYGDFSHSQLGGLHLLIGLAK 6708
R +E+ E+++ + E A H GD + +GG H +
Sbjct 3692 R---------------IEVDCREYLDDREREVAASLPHAFIGDVKGTTVGGCHHVTSRY- 3735
Query 6709 RFKESPFELEDFIPMDSTVKNYFITDAQTG-SSKCVCSVIDLLLDDFVEIIKSQDLSVVS 6767
L +P +S + + G ++K +C++ D+ L D + + S
Sbjct 3736 --------LPRVLPKESVA---VVGVSSPGKAAKALCTLTDVYLPDLEAYLHPE---TQS 3781
Query 6768 KVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQN 6827
K K+ +D+ E+ M+W +T Y +L+ L + +
Sbjct 3782 KCWKMMLDFKEVRLMVWRD----KTAYFQLEGRY-----FTWYQLASYASYIRVPVNSTV 3832
Query 6828 YGDSATLPKGIMMNVAKYT 6846
Y D P V T
Sbjct 3833 YLDPCMGPALCNRRVVGST 3851
Score = 60.9 bits (146), Expect = 7e-07, Method: Composition-based stats.
Identities = 77/403 (19%), Positives = 131/403 (33%), Gaps = 82/403 (20%)
Query 5600 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5659
+ + GPPG GK+++ + ++YT +H + + C +P
Sbjct 3287 RSRFIIGPPGAGKTYWLLQQV---QDGDVIYT-PTHQTMLDMIRALGT------CRFNVP 3336
Query 5660 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5719
A ++ F V S +V + DE + + D+ + ++
Sbjct 3337 AGTTLQ----FPVPSRTGPWVRILAGGWCPGKNSFL--DEAAYCNHLDVLRLLSKTT--- 3387
Query 5720 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5779
+GD QL P F+S C + I P L T R I D +
Sbjct 3388 LTCLGDFKQL------------HPVGFDSHCYVF-DIMPQTQLKTIWRFGQNICDAIQPD 3434
Query 5780 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5839
Y +KL S +N ++ V + R ++PY
Sbjct 3435 -YRDKL-----------------------MSMVNTTRVTYVEK------PVRYGQVLTPY 3464
Query 5840 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCI 5899
+ T+DSSQG+ +D V T T S N R VAITRA+ I
Sbjct 3465 HRDRED-------DAITIDSSQGATFDVV--TLHLPTKDSLNRQRALVAITRARHAIFVY 3515
Query 5900 MSDRDLYDKLQF----TSLEIPRRNVATLQAENVTGLFKDCS-KVITGLHPTQAPTHLSV 5954
R L T + + L + K+C+ G T V
Sbjct 3516 DPHRQLQGLFDLPAKGTPVNLAVHRDGQLIVLDRNN--KECTVAQALGNGDKFRATDKRV 3573
Query 5955 DTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
+ +C D+ G + ++ +GF + + + +
Sbjct 3574 VDSLRA--ICADLEGSSSPLP--KVAHNLGFYFSPDLTQFAKL 3612
>sp|Q4R678|GDAP2_MACFA Ganglioside-induced differentiation-associated
protein 2 OS=Macaca fascicularis OX=9541 GN=GDAP2 PE=2
SV=1
Length=461
Score = 72.8 bits (177), Expect = 6e-11, Method: Composition-based stats.
Identities = 37/201 (18%), Positives = 72/201 (36%), Gaps = 30/201 (15%)
Query 1047 EEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLS 1106
+E T +VN +N L V+ ++ ++ + + + G + +
Sbjct 25 DELNSSDTTAIVNTSNESLTDKNPVSESIFMLAGPDLKED----LQKLKGCRTGEAKLTK 80
Query 1107 GHNL-AKHCLHVVGPNVN---KGEDIQLLKSAYENFNQH------EVLLAPLLSAGIFGA 1156
G NL A+ +H VGP + L S Y N Q + ++++ G
Sbjct 81 GFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGY 140
Query 1157 DPIHSLRVCVDTVR----------TNVYLAVFD--KNLYDKLVSSFLEMKSEKQVEQKIA 1204
+ + + TVR V AV D + Y KL+ + + ++++
Sbjct 141 PLEDATHIALRTVRRFLEIHGETIEKVVFAVSDLEEATYQKLLPLYF----PRSLKEENR 196
Query 1205 EIPKEEVKPFITESKPSVEQR 1225
+P E +P V +R
Sbjct 197 SLPYLPADIGNAEGEPVVPER 217
>sp|Q68772|RPOA_SHFV Replicase polyprotein 1ab OS=Simian hemorrhagic
fever virus OX=38143 GN=rep PE=2 SV=4
Length=3595
Score = 73.2 bits (178), Expect = 1e-10, Method: Composition-based stats.
Identities = 100/563 (18%), Positives = 182/563 (32%), Gaps = 113/563 (20%)
Query 4833 FFAQDG--NAAISDYDYYRYNLPTMCDIRQLLFVVEV----VDKYFDCYDGGCINANQVI 4886
++ Q G AA+ D + + L V + Y + +N
Sbjct 2333 YYTQHGCEAAALQDLKKFNLSTQGFILPEVLNIVRNYLLGTIGYRPAIYKPSTVPSND-- 2390
Query 4887 VNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRA 4946
+ N + ++ D D L V T+T + LK +K +
Sbjct 2391 -------SHAGINGLSFSTKTLQALP--DIDELCEKAIAEVWQTVTPVTLKKQFCSKAKT 2441
Query 4947 RTVAGVSICSTMTNRQFHQKLLKSI-AATRGATVVIGTSKFYGGWHNMLKTVYSDVENPH 5005
RT+ G + +++ R + + A + + + +G SKF D
Sbjct 2442 RTILGTNAMASLALRALLSGVTQGFQLAGKNSPICLGKSKF-------------DPCTFE 2488
Query 5006 LMG----WDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMC 5061
+ G D CDR+ P ++R A+ +L C + Y + N C ++++
Sbjct 2489 VKGRCLETDLASCDRSTPAIVRHFATKLLFE--MACAERALPLY-VVNCCH----DLIVT 2541
Query 5062 GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRL-Y 5120
S K GG SSGD T+ AN+++++ V V LL +G+ ++ L +L +
Sbjct 2542 QTSAATKRGGLSSGDPVTSIANTIYSLVLYVQHMVLTLLE-NGHP---LSLKFLSGKLNF 2597
Query 5121 ECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKS---V 5177
+ LY+ + A + ++ + NF+
Sbjct 2598 QDLYKLQ--------------------------AFIVYSDDLILLNESDDLPNFERWVPH 2631
Query 5178 LYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVD 5237
L + K ++ E+ +H LV P R+L A +
Sbjct 2632 LELALGFKVDPKKTVITSNPGFLGCEY--RHGWLV-----------PQKQRVLAALAYHV 2678
Query 5238 DIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSV 5297
+ + ++ DA L+ + D+ RK D YS
Sbjct 2679 NAKDVHTYYINA--TAILNDASALSAFEPDWFDDLVIGLADCARK----------DGYSF 2726
Query 5298 MLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDH 5357
+ Y+ +Q C ++T+ CG LC C + H
Sbjct 2727 PGPAAFREFFSRVSGYQFEGKE---VQVCSIC-CSTARTTSLCG-----MALCDFCAHRH 2777
Query 5358 VISTSHKLVLSVNP-YVCNAPGC 5379
H VLS +V + C
Sbjct 2778 YHPGCH--VLSSFCKHVIGSNTC 2798
Score = 70.9 bits (172), Expect = 7e-10, Method: Composition-based stats.
Identities = 40/209 (19%), Positives = 80/209 (38%), Gaps = 36/209 (17%)
Query 6590 RNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQS 6649
N ++++ + L + +G T + K +DG + ++ ++
Sbjct 3243 PNRLVVSATRLSPLSHPAVCAGYYVGDSLFVGTPNVTSYWLTKFLDGRAVPMEDSVYSTG 3302
Query 6650 RNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKR 6709
R + D+L+ A +F ++ H GD + +GG H +
Sbjct 3303 RFEMDI-------RDYLDSAERDFAAKH-------PHAFIGDTKGTTVGGCHHITSQY-- 3346
Query 6710 FKESPFELEDFIPMDSTVKNYFITDAQTG-SSKCVCSVIDLLLDDFVEIIKSQDL-SVVS 6767
L +P DS VK + ++ G + K +C+V D+ ++ ++ S S
Sbjct 3347 -------LPHVLPADSVVK---VGVSKPGVAHKALCTVTDI----YLPMLGSYTSPPTQS 3392
Query 6768 KVVKVTIDYTEISFMLWCKDGHVETFYPK 6796
KV KV +D+ M+W +T Y +
Sbjct 3393 KVYKVNVDHKACKLMVWRD----QTMYFQ 3417
Score = 55.5 bits (132), Expect = 3e-05, Method: Composition-based stats.
Identities = 76/397 (19%), Positives = 118/397 (30%), Gaps = 81/397 (20%)
Query 5603 TLQGPPGTGKSHFAIGL----ALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5658
+ GPPG+GK+ F L A+ Y + A S + A + +
Sbjct 2894 FVVGPPGSGKTTFISNLLDDDAVVYCPTHVSLIAYSKSLPAA-------RFSVPRGQD-- 2944
Query 5659 PARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK 5718
PA + YV + L DE A +D+ + ++
Sbjct 2945 PAEYGTPALSGPTLQLLSAGYVPGAKHYL----------DEACYANPFDVFKLLSKTP-- 2992
Query 5719 HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSA 5778
IGDPAQL T + + V LMK L R I + +
Sbjct 2993 -ITAIGDPAQL-------TPVGFDTPLY--VFELMK----KNALHAIYRFGQNICNAIQP 3038
Query 5779 LVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISP 5838
Y KL +++ Q F T+ + ++P
Sbjct 3039 -CYSTKL--------------------------VSQRQGDTEVIFQTKFAP--RGKVLTP 3069
Query 5839 YNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILC 5898
Y+ A+ T+DSSQGS YD V T T S + R V ITRA+ +
Sbjct 3070 YHRDRVGAA-------VTIDSSQGSTYDVV--TLYLPTKGSLTLARGLVGITRARERLYV 3120
Query 5899 IMSDRDLYDKLQFTSLEIPRRNVA-TLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTK 5957
L R A + + L C +
Sbjct 3121 YDPHHQLAKYFNLQPSSTTIRPHAVVIDGKARVMLSDKCYAAPEDFPGMLCTARPATAAD 3180
Query 5958 FKT-EGLCVDIPGIPKD--MTYRRLISMMGFKMNYQV 5991
K E C+ + + R+ +GF + +
Sbjct 3181 RKILEETCLKLDFLESGSLSPLPRVCYNLGFYYSPDI 3217
>sp|Q460N3|PAR15_HUMAN Protein mono-ADP-ribosyltransferase PARP15
OS=Homo sapiens OX=9606 GN=PARP15 PE=1 SV=2
Length=678
Score = 72.4 bits (176), Expect = 1e-10, Method: Composition-based stats.
Identities = 38/231 (16%), Positives = 76/231 (33%), Gaps = 31/231 (13%)
Query 1037 NVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGG-VAGALNKATNNAMQVESDDYIATNG 1095
N+ + + D++ + V+VN+ + L+ GGG ++ A + +Q E DD
Sbjct 90 NLKLISGDVL----YIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDD-RRRET 144
Query 1096 PLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGED------IQLLKSAYE--NFNQHEVLLA 1146
KVG + SG NL K LH V P N G + ++K +
Sbjct 145 EEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSITF 204
Query 1147 PLLSAGIFGADPIHSLRVCVDTVRT---------------NVYLAVFDKNLYDKLVSSFL 1191
P++ G ++ + V + + D + F
Sbjct 205 PMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAFLDEFT 264
Query 1192 EMKSEKQVEQKIA-EIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTT 1241
+ +I + V +++ + + K + ++ T
Sbjct 265 NWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIAT 315
Score = 52.4 bits (124), Expect = 1e-04, Method: Composition-based stats.
Identities = 34/196 (17%), Positives = 67/196 (34%), Gaps = 28/196 (14%)
Query 1019 VVQTIEVNSFSGYLKLTDNVYIKN--ADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALN 1076
VV T+ F+ Y + + DI E + V+VN+ GV+ A+
Sbjct 285 VVGTVSKPCFTAYEMKIGAITFQVATGDIATE----QVDVIVNSTARTFNRKSGVSRAIL 340
Query 1077 KATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAY 1135
+ A++ E A + G L K +HV G + +L+
Sbjct 341 EGAGQAVESECAVLAAQ----PHRDFIITPGGCLKCKIIIHVPGGKDVRKTVTSVLEECE 396
Query 1136 ENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVR-----------TNVYLAVFDKNLYD 1184
+ ++ + P + G G +PI +D + V + +F
Sbjct 397 Q--RKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKTVKVVIFQPE--- 451
Query 1185 KLVSSFLEMKSEKQVE 1200
L++ F + ++ +
Sbjct 452 -LLNIFYDSMKKRDLS 466
>sp|Q6J5K9|ARMI_DROME Probable RNA helicase armi OS=Drosophila
melanogaster OX=7227 GN=armi PE=1 SV=4
Length=1188
Score = 71.6 bits (174), Expect = 3e-10, Method: Composition-based stats.
Identities = 73/437 (17%), Positives = 128/437 (29%), Gaps = 123/437 (28%)
Query 5577 YPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAI----GLALYYPSARIVYTA 5632
NI + N+ L GPPG+GK+ I L P ARI+
Sbjct 704 RAVFNILRGEAENIPY----------VLFGPPGSGKTMTLIETLLQLVRNLPGARILVGT 753
Query 5633 CSHAAVDALCEKAL--KYLPIDKCSRIIPAR---------------------ARVECFDK 5669
S+++ D + ++ + K L R++ A C DK
Sbjct 754 PSNSSADLVTKRLIDSKALLQGDFIRLVSYNQVEKDLIPPEIMSYCATSDVGAVGSCEDK 813
Query 5670 FKVNST------------LEQYVFCTVNAL--------PETTADIVVFDEISMATNYD-- 5707
V + + T L P V+FDE T +
Sbjct 814 MMVTESGLKLRCQAKFIGTHRITISTCTTLGNFLQLGFPAGHFTHVLFDEAGQCTEPETM 873
Query 5708 LSVVNARLRAKHYVYIGDPAQLPAPRT--LLTKGTLEPEYFNSVCRLMK----------- 5754
+ +V + V GDP QL + T + +K + +
Sbjct 874 VPIVMLTKKRSQVVLSGDPRQLQSIVTSRIASKMGFSISFLERLLERSPYRKDLQRFPES 933
Query 5755 TIGPDMFLGTC---RRCPAEIVDTVSALVYDNKLKAHKDK----------SAQC------ 5795
+ + L R I+ S L YD++L + +C
Sbjct 934 SGYNPLVLTKLLYNYRALPSIMSIYSRLFYDDELIPVLSEKDSRESRLLSKLRCVFESEK 993
Query 5796 ----------FKMFYKGVITHDVSSAINRPQIGVV----REFLTRNPAWRKAVFISPYNS 5841
+ + + +D S N ++ V N + I+PY
Sbjct 994 DIPQAHGTFFYGIIGENRQNNDSPSWFNPQEVREVFLMTIALYRANVTADQIGIITPYQK 1053
Query 5842 QNAVASKI-LGLP-----TQTVDSSQGSEYDYVIFTQTTET------------AHSCNVN 5883
Q + + +G +V+ QG E D ++ + +
Sbjct 1054 QVKMLRSMFIGTDVVMPKIGSVEEFQGQERDIILISTVRSSEEILRMDARFSLGFVRCSK 1113
Query 5884 RFNVAITRAKVGILCIM 5900
R NVA++RA+ ++
Sbjct 1114 RLNVAVSRARAMMIIFG 1130
>sp|O74465|HRR1_SCHPO Helicase required for RNAi-mediated heterochromatin
assembly 1 OS=Schizosaccharomyces pombe (strain
972 / ATCC 24843) OX=284812 GN=hrr1 PE=1 SV=2
Length=999
Score = 69.3 bits (168), Expect = 1e-09, Method: Composition-based stats.
Identities = 43/250 (17%), Positives = 83/250 (33%), Gaps = 29/250 (12%)
Query 5687 LPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYF 5746
L I +E + + + V IGD QL +
Sbjct 700 LERINPKICFIEEAADVLEGPIIPAVFP-SLEQLVLIGDHKQLRPGCSTYALRQDPFNLS 758
Query 5747 NSVCRLMKTIGPDMF-LGTCRRCPAEIVDTVSALVYDN------KLKAHKDKSAQCFKMF 5799
S+ + + L RR +I VS++ D K + + F
Sbjct 759 ISMFERLVENDMEYTRLTMQRRMHPQIRRLVSSVYEDLSDYEITKYWPSIPGMGEIRRFF 818
Query 5800 YKGVITHDV---SSAINRPQIGVVREF----LTRNPAWRKAVFISPYNSQNAVASKILG- 5851
D +S IN + ++ +F + +K ++ Y +Q + ++L
Sbjct 819 LTHSRIEDNDGFASKINLFEAQMLVQFAVYLINNGVEPQKITCLTFYAAQKDLIERLLSE 878
Query 5852 --------LPTQTVDSSQGSEYDYVIFTQT-----TETAHSCNVNRFNVAITRAKVGILC 5898
+ TVD QG E D V+ + TE + +R V+++RA+ G+
Sbjct 879 SLNREKHFIKVATVDGYQGEENDVVLLSLVRNNDRTEVGFLSSPHRVCVSLSRARRGLFI 938
Query 5899 IMSDRDLYDK 5908
+ + + +
Sbjct 939 FGNAQLVAES 948
>sp|A0MD28|RPOA_PRRSS Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (isolate Pig/United
States/SD 01-08/2001) OX=857306 PE=1 SV=2
Length=3838
Score = 69.3 bits (168), Expect = 2e-09, Method: Composition-based stats.
Identities = 80/436 (18%), Positives = 148/436 (34%), Gaps = 68/436 (16%)
Query 4840 AAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFN 4899
AA D Y + L V + + G + K++ N
Sbjct 2617 AAAEDLQKYDLSTQGFVLPGVLRLVRRFIFGHI-----GKAPPLFLPSTYPAKNSMAGIN 2671
Query 4900 KWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMT 4959
G+ D S + D + A + T+T LK +K + RT+ G + +
Sbjct 2672 --GQRFPTKDVQSIPEIDEMCARAVKENWQTVTPCTLKKQYCSKPKTRTILGTNNFIALA 2729
Query 4960 NRQFHQKLLKSIAATR-GATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAM 5018
+R + ++ + + +G +KF K ++ V L D CDR+
Sbjct 2730 HRSALSGVTQAFMKKAWKSPIALGKNKF--------KELHCTVAGRCL-EADLASCDRST 2780
Query 5019 PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDAT 5078
P ++R + +L C + + N C ++V + K GG SSGD
Sbjct 2781 PAIVRWFVANLLYEL-AGCEEYLPSY--VLNCCH----DLVATQDGAFTKRGGLSSGDPV 2833
Query 5079 TAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFY 5138
T+ +N+V+++ QH + L ++ F+ E
Sbjct 2834 TSVSNTVYSLIIY-----------------------AQHMVLSALKMGHEIGLKFLEEQL 2870
Query 5139 AY--LRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETD 5196
+ L + M++ SDD V+ YA + + + L K T
Sbjct 2871 KFEDLLEIQPMLVYSDDLVL-----YAERPTFPNYHWWVEHLDLMLGFRTDPKK----TV 2921
Query 5197 LTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAI 5256
+T P S ++ G V P+ RIL A + + + + ++ +
Sbjct 2922 ITDKP----SFLGCRIEAGRQLV----PNRDRILAALAY--HMKAQNASEYYASAAAILM 2971
Query 5257 DAYPLTKHPNQEYADV 5272
D+ H + Y D+
Sbjct 2972 DSCACIDHDPEWYEDL 2987
Score = 59.7 bits (143), Expect = 1e-06, Method: Composition-based stats.
Identities = 66/396 (17%), Positives = 119/396 (30%), Gaps = 73/396 (18%)
Query 5603 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA 5662
+ GPPG+GK+ + + ++YT D + + I S +
Sbjct 3166 FIVGPPGSGKTTWLLSQV---QDDDVIYTPTHQTMFDIVSALKVCRYSIPGASGL----- 3217
Query 5663 RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY 5722
+ +P T+ DE + D+ + ++ V
Sbjct 3218 -----PFPPPARSGPWVRLVASGHVPGRTS---YLDEAGYCNHLDILRLLSKTP---LVC 3266
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5782
+GD QL P F+S C + + P L T R I + Y
Sbjct 3267 LGDLQQL------------HPVGFDSYCYVFDQM-PQKQLTTIYRFGPNICAAIQP-CYR 3312
Query 5783 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5842
KL++ + F + ++PY+
Sbjct 3313 EKLESKARNTRVVFTTW-----------------------------PVAFGQVLTPYHKD 3343
Query 5843 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSD 5902
+G T+DSSQG+ +D I T + S N +R VAITRA+ G+
Sbjct 3344 R------IGSAI-TIDSSQGATFD--IVTLHLPSPKSLNKSRALVAITRARHGLFIYDPH 3394
Query 5903 RDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG 5962
L + E N+ + +++ L D + P+ V
Sbjct 3395 NQLQEFFNLIP-ERTDCNLVFSRGDDLVVLSADNAVTTVAKALGTGPSRFRVSDPRCKSL 3453
Query 5963 LCVDIPGIPKDM-TYRRLISMMGFKMNYQVNGYPNM 5997
L + ++ +GF + + +
Sbjct 3454 LAACSASLEGSCMPLPQVAHNLGFYFSPDSPAFAPL 3489
Score = 55.5 bits (132), Expect = 3e-05, Method: Composition-based stats.
Identities = 43/237 (18%), Positives = 79/237 (33%), Gaps = 42/237 (18%)
Query 6612 ASLNGVTLIGEAVKT-QFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAM 6670
+ G + + + G Q LPET + R + ++L+ A
Sbjct 3531 GYVVGPSTFLGTPGVVSYYLTLYIRGEPQALPETLVSTGRIATDC-------REYLDAAE 3583
Query 6671 DEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNY 6730
+ H GD + +GG H + L +P DS
Sbjct 3584 -------EEAAKELPHAFIGDVKGTTVGGCHHITSKY---------LPRTLPKDSVA--- 3624
Query 6731 FITDAQTGS-SKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGH 6789
+ + G +K +C++ D+ L + ++ + SK K+ +D+ ++ M+W
Sbjct 3625 VVGVSSPGRAAKAMCTLTDVYLPELRPYLQPE---TASKCWKLKLDFRDVRLMVW----K 3677
Query 6790 VETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYT 6846
T Y +L+ G+ L R + D Y D P V + T
Sbjct 3678 GATAYFQLE-------GLTWSALPDYARFIQLPKDAVVYIDPCIGPATANRKVVRTT 3727
>sp|Q8CCK0|H2AW_MOUSE Core histone macro-H2A.2 OS=Mus musculus
OX=10090 GN=Macroh2a2 PE=1 SV=3
Length=372
Score = 67.4 bits (163), Expect = 2e-09, Method: Composition-based stats.
Identities = 35/187 (19%), Positives = 64/187 (34%), Gaps = 23/187 (12%)
Query 1029 SGYLKLTDNVYIKNADIVEEAKKVKPTVVVNA--ANVYLKHGGGVAGALNKATNNAMQVE 1086
S L L + + +DI ++ +V+ A + LK G AL KA
Sbjct 188 SKSLVLGQKLSLTQSDISHIG-SMRVEGIVHPTTAEIDLKEEIG--KALEKAGGKEFLET 244
Query 1087 SDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYEN------FN 1139
+ + GPL+V + V L AK +H P + + L+ +N
Sbjct 245 VKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSAAEDK 304
Query 1140 QHEVLLAPLLSAGIFGADPIHSLRVCVDTVR-----------TNVYLAVFDKNLYDKLVS 1188
+ + + P +G + +V + + NVY +FD V
Sbjct 305 KLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSSSSLKNVYFLLFDSESIGIYVQ 364
Query 1189 SFLEMKS 1195
++ +
Sbjct 365 EMAKLDT 371
>sp|Q9P0M6|H2AW_HUMAN Core histone macro-H2A.2 OS=Homo sapiens
OX=9606 GN=MACROH2A2 PE=1 SV=3
Length=372
Score = 67.4 bits (163), Expect = 2e-09, Method: Composition-based stats.
Identities = 35/186 (19%), Positives = 63/186 (34%), Gaps = 23/186 (12%)
Query 1029 SGYLKLTDNVYIKNADIVEEAKKVKPTVVVNA--ANVYLKHGGGVAGALNKATNNAMQVE 1086
S L L + + +DI ++ +V+ A + LK G AL KA
Sbjct 188 SKSLVLGQKLSLTQSDISHIG-SMRVEGIVHPTTAEIDLKEDIG--KALEKAGGKEFLET 244
Query 1087 SDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAYEN------FN 1139
+ + GPL+V + V L AK +H P + + L+ +N
Sbjct 245 VKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSAAEDK 304
Query 1140 QHEVLLAPLLSAGIFGADPIHSLRVCVDTVR-----------TNVYLAVFDKNLYDKLVS 1188
+ + + P +G + +V + + NVY +FD V
Sbjct 305 KLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSASSLKNVYFLLFDSESIGIYVQ 364
Query 1189 SFLEMK 1194
++
Sbjct 365 EMAKLD 370
>sp|Q04561|RPOA_PRRSL Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain Lelystad) OX=11049
GN=rep PE=1 SV=3
Length=3855
Score = 68.6 bits (166), Expect = 3e-09, Method: Composition-based stats.
Identities = 80/436 (18%), Positives = 148/436 (34%), Gaps = 68/436 (16%)
Query 4840 AAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFN 4899
AA D Y + L V + + G + K++ N
Sbjct 2634 AAAEDLQKYDLSTQGFVLPGVLRLVRRFIFGHI-----GKAPPLFLPSTYPAKNSMAGIN 2688
Query 4900 KWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMT 4959
G+ D S + D + A + T+T LK +K + RT+ G + +
Sbjct 2689 --GQRFPTKDVQSIPEIDEMCARAVKENWQTVTPCTLKKQYCSKPKTRTILGTNNFIALA 2746
Query 4960 NRQFHQKLLKSIAATR-GATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAM 5018
+R + ++ + + +G +KF K ++ V L D CDR+
Sbjct 2747 HRSALSGVTQAFMKKAWKSPIALGKNKF--------KELHCTVAGRCL-EADLASCDRST 2797
Query 5019 PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDAT 5078
P ++R + +L C + + N C ++V + K GG SSGD
Sbjct 2798 PAIVRWFVANLLYEL-AGCEEYLPSY--VLNCCH----DLVATQDGAFTKRGGLSSGDPV 2850
Query 5079 TAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFY 5138
T+ +N+V+++ QH + L ++ F+ E
Sbjct 2851 TSVSNTVYSLVIY-----------------------AQHMVLSALKMGHEIGLKFLEEQL 2887
Query 5139 AY--LRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETD 5196
+ L + M++ SDD V+ YA + + + L K T
Sbjct 2888 KFEDLLEIQPMLVYSDDLVL-----YAERPTFPNYHWWVEHLDLMLGFRTDPKK----TV 2938
Query 5197 LTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAI 5256
+T P S ++ G V P+ RIL A + + + + ++ +
Sbjct 2939 ITDKP----SFLGCRIEAGRQLV----PNRDRILAALAY--HMKAQNASEYYASAAAILM 2988
Query 5257 DAYPLTKHPNQEYADV 5272
D+ H + Y D+
Sbjct 2989 DSCACIDHDPEWYEDL 3004
Score = 59.3 bits (142), Expect = 2e-06, Method: Composition-based stats.
Identities = 66/396 (17%), Positives = 117/396 (30%), Gaps = 73/396 (18%)
Query 5603 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA 5662
+ GPPG+GK+ + + ++YT D + + I S +
Sbjct 3183 FIVGPPGSGKTTWLLSQV---QDDDVIYTPTHQTMFDIVSALKVCRYSIPGASGL----- 3234
Query 5663 RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY 5722
+ +P + DE + D+ + ++ V
Sbjct 3235 -----PFPPPARSGPWVRLIASGHVP---GRVSYLDEAGYCNHLDILRLLSKTP---LVC 3283
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5782
+GD QL P F+S C + + P L T R I + Y
Sbjct 3284 LGDLQQL------------HPVGFDSYCYVFDQM-PQKQLTTIYRFGPNICAAIQP-CYR 3329
Query 5783 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5842
KL++ + F ++PY+
Sbjct 3330 EKLESKARNTRVVF-----------------------------TTRPVAFGQVLTPYHKD 3360
Query 5843 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSD 5902
+G T+DSSQG+ +D I T + S N +R VAITRA+ G+
Sbjct 3361 R------IGSAI-TIDSSQGATFD--IVTLHLPSPKSLNKSRALVAITRARHGLFIYDPH 3411
Query 5903 RDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG 5962
L + T E N+ + + + L D + P+ V
Sbjct 3412 NQLQEFFNLTP-ERTDCNLVFSRGDELVVLNADNAVTTVAKALETGPSRFRVSDPRCKSL 3470
Query 5963 LCVDIPGIPKDM-TYRRLISMMGFKMNYQVNGYPNM 5997
L + ++ +GF + + +
Sbjct 3471 LAACSASLEGSCMPLPQVAHNLGFYFSPDSPTFAPL 3506
Score = 56.6 bits (135), Expect = 1e-05, Method: Composition-based stats.
Identities = 44/237 (19%), Positives = 79/237 (33%), Gaps = 42/237 (18%)
Query 6612 ASLNGVTLIGEAVKT-QFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAM 6670
+ G + + + G Q LPET + R + ++L+ A
Sbjct 3548 GYVVGPSTFLGTPGVVSYYLTLYIRGEPQALPETLVSTGRIATDC-------REYLDAAE 3600
Query 6671 DEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNY 6730
+ H GD + +GG H + L +P DS
Sbjct 3601 -------EEAAKELPHAFIGDVKGTTVGGCHHITSKY---------LPRSLPKDSVA--- 3641
Query 6731 FITDAQTGS-SKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGH 6789
+ + G +K VC++ D+ L + ++ + SK K+ +D+ ++ M+W
Sbjct 3642 VVGVSSPGRAAKAVCTLTDVYLPELRPYLQPE---TASKCWKLKLDFRDVRLMVW----K 3694
Query 6790 VETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYT 6846
T Y +L+ G+ L R + D Y D P V + T
Sbjct 3695 GATAYFQLE-------GLTWSALPDYARFIQLPKDAVVYIDPCIGPATANRKVVRTT 3744
>sp|F6QXW0|DNA2_XENTR DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Xenopus tropicalis OX=8364 GN=dna2 PE=3 SV=1
Length=1048
Score = 67.8 bits (164), Expect = 4e-09, Method: Composition-based stats.
Identities = 66/387 (17%), Positives = 116/387 (30%), Gaps = 92/387 (24%)
Query 5599 QKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5658
+ Y+ + G PGTGK+ L + + C+ VD E A + +
Sbjct 642 KDYTLIVGMPGTGKTTTICTLV-----STLHLKTCTSCLVDDHREAAGTHRSHRHSKGTV 696
Query 5659 ------------------PARARVECFDKFKVNSTLEQYVFC------TVNALPETTAD- 5693
A+ R + + Q + VN + +
Sbjct 697 NLGKQKRQHRVTSTTSSTSAKCRSKTEPAVSAENKKLQKLISGSHVCIMVNGHKTFSQNN 756
Query 5694 -IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRL 5752
I+ FD I + L + A H + G +L+ + + F + R
Sbjct 757 YIIFFDNILLLKKLPLHYMCAFALIHHQCFKG----CVKSVSLVRELGMSESLFKRLERN 812
Query 5753 MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD---------------------- 5790
+ + L R ++I+ + LVY+ +L+ D
Sbjct 813 QEAVVQ---LTVQYRMNSQIMALSNKLVYEGRLECASDRVSNAVVKLPHIKTLLLELEFR 869
Query 5791 --------------KSAQCFKMFYK--GVITHDVSSAINRPQIGVV----REFLTRNPAW 5830
+ CF K + T + N + +V + FL
Sbjct 870 ESQESMWIKDVLEPSNPVCFLNTEKIPALETEEKGGISNWIEAKLVFCLTKLFLKAGCRP 929
Query 5831 RKAVFISPYNSQ-----NAVAS-KILGLPTQTVDSSQGSEYDYVIFT-QTTETA-----H 5878
I+PY Q N S + TVD QG + +I + +
Sbjct 930 SDIGIIAPYRQQLKVISNYFNSLSASAVEVNTVDKYQGRDKSVIIVSFVRSNIDGKLGDL 989
Query 5879 SCNVNRFNVAITRAKVGILCIMSDRDL 5905
+ R NVA+TRAK ++ + L
Sbjct 990 LKDWRRLNVALTRAKHKLIMLGCVPTL 1016
>sp|Q7JUR6|GDAP2_DROME Protein GDAP2 homolog OS=Drosophila melanogaster
OX=7227 GN=Gdap2 PE=2 SV=1
Length=540
Score = 66.6 bits (161), Expect = 6e-09, Method: Composition-based stats.
Identities = 32/229 (14%), Positives = 69/229 (30%), Gaps = 34/229 (15%)
Query 1025 VNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQ 1084
+ F + + I + D+ ++ + N ++ L ++ + N ++
Sbjct 56 RSPFPLCKDVNNRFVIWDGDMT----TLEVDAITNTSDETLTESNSISERIFAVAGNQLR 111
Query 1085 VESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVN---KGEDIQLLKSAYENF-- 1138
E + + G + G+NL AK+ LH V P K L Y N
Sbjct 112 EELSTTVK---ECRTGDVRITRGYNLPAKYVLHTVAPAYREKFKTAAENTLHCCYRNVLC 168
Query 1139 ----NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT-------NVYLAVFDKNL---YD 1184
+ +SA + + + T+R V + + Y+
Sbjct 169 KAKELNLHTIALCNISAHQKSFPADVAAHIALRTIRRYLDKCTLQVVILCVGSSERGTYE 228
Query 1185 KLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIK 1233
L + ++ + K + Q D++I+
Sbjct 229 VLAPLYFPRDQLEE-----RSALWQLPKD--IGGEFGEPQHPDPDRQIR 270
>sp|Q8CFQ3|AQR_MOUSE RNA helicase aquarius OS=Mus musculus OX=10090
GN=Aqr PE=1 SV=2
Length=1481
Score = 67.4 bits (163), Expect = 7e-09, Method: Composition-based stats.
Identities = 57/294 (19%), Positives = 98/294 (33%), Gaps = 67/294 (23%)
Query 5672 VNSTLEQYVFCTVNALPETT-------ADIVVFDEISMATNYDLSVVNARL--------R 5716
V + CT AL D ++ +E + + + + L R
Sbjct 1033 VKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIE-TFIPLLLQNPQDGFSR 1091
Query 5717 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRR-----CP-- 5769
K ++ IGD QLP + + R ++ P + L R C
Sbjct 1092 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 1151
Query 5770 ----------------AEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN 5813
E + L+YD +L +D G + N
Sbjct 1152 NWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGV-------GESEPNPYFYQN 1204
Query 5814 RPQIGVVREF-----LTRNPAWRKAVFISPYNSQNAVAS----------KILGLPTQ--T 5856
+ V L PA + ++ ++ YN Q + ++G P + T
Sbjct 1205 LGEAEYVVALFMYMCLLGYPADKISI-LTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTT 1263
Query 5857 VDSSQGSEYDYVIFTQ--TTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDK 5908
VD QG + DY++ + T H +V R VA++RA++G L I + L+
Sbjct 1264 VDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLG-LYIFARVSLFQN 1316
>sp|O60306|AQR_HUMAN RNA helicase aquarius OS=Homo sapiens OX=9606
GN=AQR PE=1 SV=4
Length=1485
Score = 67.4 bits (163), Expect = 7e-09, Method: Composition-based stats.
Identities = 57/294 (19%), Positives = 98/294 (33%), Gaps = 67/294 (23%)
Query 5672 VNSTLEQYVFCTVNALPETT-------ADIVVFDEISMATNYDLSVVNARL--------R 5716
V + CT AL D ++ +E + + + + L R
Sbjct 1029 VKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIE-TFIPLLLQNPQDGFSR 1087
Query 5717 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRR-----CP-- 5769
K ++ IGD QLP + + R ++ P + L R C
Sbjct 1088 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 1147
Query 5770 ----------------AEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN 5813
E + L+YD +L +D G + N
Sbjct 1148 NWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGV-------GESEPNPYFYQN 1200
Query 5814 RPQIGVVREF-----LTRNPAWRKAVFISPYNSQNAVAS----------KILGLPTQ--T 5856
+ V L PA + ++ ++ YN Q + ++G P + T
Sbjct 1201 LGEAEYVVALFMYMCLLGYPADKISI-LTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTT 1259
Query 5857 VDSSQGSEYDYVIFTQ--TTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDK 5908
VD QG + DY++ + T H +V R VA++RA++G L I + L+
Sbjct 1260 VDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLG-LYIFARVSLFQN 1312
>sp|A0A0D2UG83|H2AY_CAPO3 Histone macroH2A1.1 OS=Capsaspora owczarzaki
(strain ATCC 30864) OX=595528 GN=CAOG_004778 PE=1 SV=1
Length=368
Score = 65.1 bits (157), Expect = 1e-08, Method: Composition-based stats.
Identities = 37/181 (20%), Positives = 71/181 (39%), Gaps = 23/181 (13%)
Query 1032 LKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYI 1091
L L +Y+ N D+ E V+ VV+ N + G V GA+ A + E + Y+
Sbjct 191 LHLGQTLYVVNGDLTE----VRCDAVVHPTNGTMSFAGQVGGAIRAAAGAGVDAEVNSYM 246
Query 1092 ATNGPLKVGGSCVLSGHNLA-KHCLHVVGPNVNKGEDI-----QLLKSAYENFNQH--EV 1143
+ + L+V + + SGHNL K +HV PN + Q +++A + +
Sbjct 247 SEHSQLQVTKAAITSGHNLPSKWIVHVHSPNYSNAATATDALTQTIRNALTLADTKSIKT 306
Query 1144 LLAPLLSAGIFGADPIHSLRVCVDTVR-----------TNVYLAVFDKNLYDKLVSSFLE 1192
+ P + +G + + + + VY +FD+ + + +
Sbjct 307 IAFPSIGSGNNHFPKHIAAQTILQAISAYFMSIMSSSIKEVYFVLFDQESINVYNAELIN 366
Query 1193 M 1193
Sbjct 367 T 367
>sp|Q292F9|GDAP2_DROPS Protein GDAP2 homolog OS=Drosophila pseudoobscura
pseudoobscura OX=46245 GN=GA15091 PE=3 SV=1
Length=542
Score = 65.9 bits (159), Expect = 1e-08, Method: Composition-based stats.
Identities = 31/229 (14%), Positives = 69/229 (30%), Gaps = 34/229 (15%)
Query 1025 VNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQ 1084
+ F + + + I + D+ + + N ++ L ++ + N ++
Sbjct 58 RSPFPLSKDVNNRLVIWDGDMT----TLDVDAITNTSDETLTESNIISERILAVAGNQLR 113
Query 1085 VESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVN---KGEDIQLLKSAYENF-- 1138
E + + G + G+NL AK+ LH V P K L Y N
Sbjct 114 EELSTNVK---ECRTGDVRITRGYNLPAKYVLHTVAPTYREKFKTAAENTLHCCYRNVLC 170
Query 1139 ----NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRT-------NVYLAV---FDKNLYD 1184
+ +S + + + T+R V + ++ Y+
Sbjct 171 KAKELNLHTIALCNISVHQKSFPADVAAHIALRTIRRYLDKCTLQVVILCVNSNERGTYE 230
Query 1185 KLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIK 1233
L + ++ + K + Q D++I+
Sbjct 231 VLAPLYFPRDQLEE-----RSALWQLPKD--IGGEFGEPQHPDPDRQIR 272
>sp|Q9YLR1|POLN_HEVUS Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 3 (isolate Human/United States/US2) OX=509615
GN=ORF1 PE=3 SV=1
Length=1708
Score = 65.9 bits (159), Expect = 2e-08, Method: Composition-based stats.
Identities = 40/209 (19%), Positives = 69/209 (33%), Gaps = 24/209 (11%)
Query 957 GKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMEL 1016
G P S EE +D S +V + G IV P +
Sbjct 729 GLPYPTPPVSDIWVLPPPSEESHVDAASVPSVPEPAG-------LTSPIVLTPPPPPPPV 781
Query 1017 TPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALN 1076
+ + D + + E +VNA+N + GGG+ A
Sbjct 782 RKPATSPPPRTRRLLYTYPDGAKVYAGSLXES----DCDWLVNASNPGHRPGGGLCHAFY 837
Query 1077 KATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCLHVVGPNVNKGEDIQLLKSAY 1135
+ A S ++I G L+ + L + +H V P+ ++ + L++AY
Sbjct 838 QRFPEAF--YSTEFIMREG---------LAAYTLTPRPIIHAVAPDYRVEQNPKRLEAAY 886
Query 1136 EN-FNQHEVLLAPLLSAGIFGADPIHSLR 1163
++ PLL +GI+ S
Sbjct 887 RETCSRRGTAAYPLLGSGIYQVPVSLSFD 915
>sp|P19811|RPOA_EAVBU Replicase polyprotein 1ab OS=Equine arteritis
virus (strain Bucyrus) OX=299386 GN=rep PE=1 SV=3
Length=3175
Score = 65.9 bits (159), Expect = 2e-08, Method: Composition-based stats.
Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 37/209 (18%)
Query 6590 RNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVK-TQFNYYKKVDGVVQQLPETYFTQ 6648
N + IT V L + G ++ + T + + VDG + LP++ F+
Sbjct 2882 PNCLQITLQQVCELS--KPCSAGYMVGQSVFVQTPGVTSYWLTEWVDGKARALPDSLFSS 2939
Query 6649 SRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAK 6708
R F+ S FL+ A ++F + H G+ + S +GG H +
Sbjct 2940 GR----FETNS---RAFLDEAEEKFAAAH-------PHACLGEINKSTVGGSHFIFSQY- 2984
Query 6709 RFKESPFELEDFIPMDSTVKNYFITDAQTG-SSKCVCSVIDLLLDDFVEIIKSQDLSVVS 6767
L +P D+ + + G ++K CSV+D+ F + + L S
Sbjct 2985 --------LPPLLPADAVA---LVGASLAGKAAKAACSVVDVYAPSFEPYLHPETL---S 3030
Query 6768 KVVKVTIDYTEISFMLWCKDGHVETFYPK 6796
+V K+ ID+ M+W TFY +
Sbjct 3031 RVYKIMIDFKPCRLMVWRN----ATFYVQ 3055
Score = 52.0 bits (123), Expect = 3e-04, Method: Composition-based stats.
Identities = 69/339 (20%), Positives = 111/339 (33%), Gaps = 62/339 (18%)
Query 5575 GLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACS 5634
G + + + D V N ++GPPG+GK+ F + + +
Sbjct 2497 GSHIAVPLQDTLKGVVVNKALKNAAASEYVEGPPGSGKT-FHLVKDVLAVVGSATLVVPT 2555
Query 5635 HAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADI 5694
HA++ C LK D ++P ++ F + S V T
Sbjct 2556 HASMLD-CINKLKQAGADP-YFVVPKYTVLD-FP--RPGSGNITVRLPQVGTSEGETF-- 2608
Query 5695 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK 5754
DE++ + DL+ + + R K Y GD QL L +F S+
Sbjct 2609 --VDEVAYFSPVDLARILTQGRVKGY---GDLNQLGCVGPASVPRNLWLRHFVSLEP--- 2660
Query 5755 TIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINR 5814
L C R A + D + + + + + K+ +
Sbjct 2661 -------LRVCHRFGAAVCDLIKGIY------PYYEPAPHTTKVVF-------------- 2693
Query 5815 PQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTT 5874
NP + K V I+ Y+ GL +T+DS QG + V T
Sbjct 2694 ----------VPNPDFEKGVVITAYHKDR-------GLGHRTIDSIQGCTFPVV--TLRL 2734
Query 5875 ETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTS 5913
T S R VA+TRA + L L+FT
Sbjct 2735 PTPQSLTRPRAVVAVTRASQELYIYDPFDQLSGLLKFTK 2773
Score = 49.7 bits (117), Expect = 0.001, Method: Composition-based stats.
Identities = 54/313 (17%), Positives = 108/313 (35%), Gaps = 31/313 (10%)
Query 4785 TTCFSVA--ALTNNVA-FQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAA 4841
T C+ A+T+ T+ P + D + K + + F A
Sbjct 1911 TACYRAGCEAVTDGTNVIATIGPFPEQQPIPD--IPKSVLDNCADISCDAFIAPAAETAL 1968
Query 4842 ISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKW 4901
D + Y + V + + + D + V + + AG ++
Sbjct 1969 CGDLEKYNLSTQGFVLPSVFSMVRAYLKE--EIGDAPPLYLPST-VPSKNSQAGINGAEF 2025
Query 4902 GKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNR 4961
L SY D + + + ++ + T T K +K + R++ G + + R
Sbjct 2026 PTKSL----QSYCLIDDMVSQSMKSNLQTATMATCKRQYCSKYKIRSILGTNNYIGLGLR 2081
Query 4962 QFHQKLLKSI--AATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMP 5019
+ + A G+ + +G SKF + L D CDR+ P
Sbjct 2082 ACLSGVTAAFQKAGKDGSPIYLGKSKF---------DPIPAPDKYCL-ETDLESCDRSTP 2131
Query 5020 NMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATT 5079
++R A+ ++ + C ++V+ G + K GG SSGD T
Sbjct 2132 ALVRWFATNLIFE----LAGQPELVHSYVLNCCH---DLVVAGSVAFTKRGGLSSGDPIT 2184
Query 5080 AYANSVFNICQAV 5092
+ +N+++++
Sbjct 2185 SISNTIYSLVLYT 2197
>sp|Q06502|RPOA_LDVC Replicase polyprotein 1ab OS=Lactate dehydrogenase
elevating virus (strain C) OX=300015 GN=rep PE=3 SV=2
Length=3637
Score = 65.1 bits (157), Expect = 3e-08, Method: Composition-based stats.
Identities = 90/545 (17%), Positives = 168/545 (31%), Gaps = 97/545 (18%)
Query 4841 AISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNK 4900
A D + + L V + + + + + AG N+
Sbjct 2463 AECDLQKFDLSRQGFVLPGVLYMVRRYLCRLVGIRRRLFLPSTY---PAKNSMAGINGNR 2519
Query 4901 WGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTN 4960
+ + S+ D DAL + T+T LK +K + RT+ G + +
Sbjct 2520 FPT----HVVQSHPDIDALCERACKEHWQTVTPCTLKKQYCSKAKTRTILGTNNFVALGL 2575
Query 4961 RQFHQKLLKS-IAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMP 5019
R + + + G+ + +G +KF T + + D CDR+ P
Sbjct 2576 RSALSGVTQGFMRKGIGSPICLGKNKF---------TPLPTKVSGRCLEADLASCDRSTP 2626
Query 5020 NMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATT 5079
++R + +L + + N C +S M C + K GG SSGD T
Sbjct 2627 AIIRWFTTNLLFEL-AGPEEWIPSY--VLNCCHDAVSTMSGC----FDKRGGLSSGDPVT 2679
Query 5080 AYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYA 5139
+ +N+V+++ V + G+K+ ++R D+ + + +
Sbjct 2680 SVSNTVYSLVIYAQHMVLSAFRC-GHKVGGLFLR----------------DSLEMEQLFE 2722
Query 5140 YLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTK 5199
+++ SDD VV ++ + F L +K +D
Sbjct 2723 LQ----PLLVYSDD-VVLYDESSELPNYHF----FVDHLDLMLGFKTDRSKTVITSDPQF 2773
Query 5200 GPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAY 5259
+ ++ P RIL A + ++ +DA
Sbjct 2774 PGCRIAAGRVLV------------PQRDRILAALAYHMKASCVSDYFASA--AAILMDAC 2819
Query 5260 PLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTP 5319
+ Y D+ RK R+ P FY M+
Sbjct 2820 ACCDYDEDWYFDLVCGIADCARK--------------------EGFRFPGPSFYVDMWKR 2859
Query 5320 HTV--LQAVGACVLCNSQT--SLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCN 5375
+V + C C + + CG LC + H H V+ +
Sbjct 2860 LSVEEKKKCRTCAHCGAPSTLVSSCG-----LNLCDYHGHGH----PHCPVVLPCGHAVG 2910
Query 5376 APGCD 5380
+ CD
Sbjct 2911 SGVCD 2915
Score = 57.8 bits (138), Expect = 5e-06, Method: Composition-based stats.
Identities = 56/314 (18%), Positives = 94/314 (30%), Gaps = 71/314 (23%)
Query 5600 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5659
+ + G PGTGK+ + + + ++YT +H + + + R P
Sbjct 3007 RSQFITGAPGTGKTTYLLSVVR---DDDVIYT-PTHRTMLDVVKAL-------GTCRFDP 3055
Query 5660 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5719
+ F + T +P + DE + D+ + ++
Sbjct 3056 PKDTPLEFPV--PSRTGPCVRLIRAGFIP---GRVSYLDEAAYCNPLDVLKILSKTP--- 3107
Query 5720 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5779
V +GD QLP P F C + L R IV+
Sbjct 3108 LVCVGDLNQLP------------PVDFIGPCYAF-ALMLGRQLIEVFRFGPSIVN-PIKK 3153
Query 5780 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5839
Y +L + + +FL + ++PY
Sbjct 3154 FYREELVSRGPDTG---------------------------VKFLKSYQPY--GQVLTPY 3184
Query 5840 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCI 5899
+ + T+DSSQG YD + T S N R VAITRA+ +
Sbjct 3185 HRDRVDGA-------ITIDSSQGCTYDVITVYLP--TPKSLNSARALVAITRARFYVFVY 3235
Query 5900 MSDRDLYDKLQFTS 5913
L L +
Sbjct 3236 DPHNQLEQYLNMSE 3249
Score = 42.8 bits (99), Expect = 0.19, Method: Composition-based stats.
Identities = 33/196 (17%), Positives = 67/196 (34%), Gaps = 30/196 (15%)
Query 6590 RNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQS 6649
+ ++ + + ++ + +G + K + G LP++ +
Sbjct 3340 PDRLVCSMSKIDKCSRAIFCAGYHVGPSVFLGVPGVVSYYLTKFLKGKPVPLPDSLMSTG 3399
Query 6650 RNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKR 6709
R ++L+ EF R H G+ S +GG H +
Sbjct 3400 RIALNV-------REYLDEKEMEFSSR-------CPHAFIGEVKGSNVGGCHHVTSRY-- 3443
Query 6710 FKESPFELEDFIPMDSTVKNYFITDAQTG-SSKCVCSVIDLLLDDFVEIIKSQDLSVVSK 6768
L + S VK I + G ++K +C+V D+ L E+ + S
Sbjct 3444 -------LPPVLVPGSVVK---IGVSCPGKAAKELCTVTDVYLP---ELDPYLNPPTKSM 3490
Query 6769 VVKVTIDYTEISFMLW 6784
K+ +D+ + M+W
Sbjct 3491 DYKLLVDFQPVKLMVW 3506
>sp|Q83017|RPOA_LDVP Replicase polyprotein 1ab OS=Lactate dehydrogenase
elevating virus (strain Plagemann) OX=300016 GN=rep
PE=1 SV=2
Length=3616
Score = 63.2 bits (152), Expect = 1e-07, Method: Composition-based stats.
Identities = 63/313 (20%), Positives = 112/313 (36%), Gaps = 28/313 (9%)
Query 4837 DGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGF 4896
+AA D + + L V + + + + K++
Sbjct 2438 CASAAEKDLQKFDLSRQGFVLPGVLYMVRRYLSRLIGVRRRLFMPSTYPA-----KNSMA 2492
Query 4897 PFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICS 4956
N G+ L + S+ D DAL T+T LK +K++ RT+ G +
Sbjct 2493 GING-GRFPLTWLQ-SHPDIDALCKRACEEHWQTVTPCTLKKQYCSKSKTRTILGTNNFV 2550
Query 4957 TMTNRQFHQKLLKS-IAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCD 5015
+ R + + + G + +G +KF T + D CD
Sbjct 2551 ALGLRSALSGVTQGFMRKGIGTPICLGKNKF---------TPLPVRIGGRCLEADLASCD 2601
Query 5016 RAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSG 5075
R+ P ++R + +L + + N C V+S M C + K GG SSG
Sbjct 2602 RSTPAIIRWFTTNLLFEL-AGAEEWIPSY--VLNCCHDVVSTMSGC----FDKRGGLSSG 2654
Query 5076 DATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNL--QHRLYE-CLYRNRDVDTD 5132
D T+ +N+V+++ V + G+KI ++++ +L+E D
Sbjct 2655 DPVTSISNTVYSLIIYAQHMVLSAFRC-GHKIGGLFLQDSLEMEQLFELQPLLVYSDDVV 2713
Query 5133 FVNEFYAYLRKHF 5145
F NE HF
Sbjct 2714 FYNESDELPNYHF 2726
Score = 63.2 bits (152), Expect = 1e-07, Method: Composition-based stats.
Identities = 63/314 (20%), Positives = 101/314 (32%), Gaps = 71/314 (23%)
Query 5600 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5659
+ + G PGTGK+ + + + ++YT +H + + KALK D P
Sbjct 2986 RSQFVTGAPGTGKTTYLLSVVR---DDDVIYT-PTHRTMLDV-VKALKVCRFD------P 3034
Query 5660 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5719
+ F T +P + DE + D+ V ++
Sbjct 3035 PKDTPLEFPV--PGRTGPTVRLIGAGFVP---GRVSYLDEAAYCNPLDVLKVLSKTP--- 3086
Query 5720 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5779
V +GD QLP P FN C ++ P L R +V+++
Sbjct 3087 LVCVGDLNQLP------------PVGFNGPCFAF-SLMPGRQLIEVFRFGPAVVNSI-KK 3132
Query 5780 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5839
Y +L + +FL + + ++PY
Sbjct 3133 FYKEELVPRGPDTG---------------------------VKFLKQYQPY--GQVLTPY 3163
Query 5840 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCI 5899
+ + T+DSSQG YD V T S N R VA+TRA+ +
Sbjct 3164 HRDRVDGA-------ITIDSSQGCTYDVVTVYLP--TPKSLNSARALVALTRARHYVFIY 3214
Query 5900 MSDRDLYDKLQFTS 5913
L LQ
Sbjct 3215 DPYDQLQQYLQVFE 3228
Score = 38.5 bits (88), Expect = 3.6, Method: Composition-based stats.
Identities = 34/190 (18%), Positives = 66/190 (35%), Gaps = 37/190 (19%)
Query 6596 TEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEF 6655
+V VGP GV + + K + G LP++ + R
Sbjct 3332 NSRAVFCAGYYVGPS--IFLGVPGVVS-----YYLTKYLKGESVPLPDSIMSTGRIRLNV 3384
Query 6656 KPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPF 6715
++L+ EF ++ G+ S +GG H +
Sbjct 3385 -------REYLDENEIEFAKK-------CPQPFIGEVKGSNVGGCHHVTSRF-------- 3422
Query 6716 ELEDFIPMDSTVKNYFITDAQTG-SSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTI 6774
L + S VK + + G ++K +C+V D+ L + + S+ K++ +
Sbjct 3423 -LPPVLVPGSVVK---VGVSCPGKAAKGLCTVTDVYLPELDSYLHPPSKSMDYKLL---V 3475
Query 6775 DYTEISFMLW 6784
D+ + M+W
Sbjct 3476 DFQPVKLMVW 3485
>sp|P42694|HELZ_HUMAN Probable helicase with zinc finger domain
OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2
Length=1942
Score = 62.4 bits (150), Expect = 2e-07, Method: Composition-based stats.
Identities = 72/394 (18%), Positives = 117/394 (30%), Gaps = 93/394 (24%)
Query 5602 STLQGPPGTGKSHF---AIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5658
+ GP GTGK+ A+ L RI+ S++A D + L +
Sbjct 664 VLIIGPYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQAR 723
Query 5659 PARARVECFDKF-------------------------KVNSTLEQYVFCTVNA---LPET 5690
P RV +++ K + + V T+N L +
Sbjct 724 P--LRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQL 781
Query 5691 T-----ADIVVFDEISMATNYDLSV-VNARLRAKHYVYIGDPAQLPAPRT--LLTKGTLE 5742
++ DE + A + + + + V GD QL + L
Sbjct 782 DLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLH 841
Query 5743 PEYFNSVCRLMKTIGP-DMFLGTCRRCPAEIVDTVSALVYDNKLK------AHKDKSAQC 5795
+ + P + L R I++ S L Y+ KL AHKD
Sbjct 842 VSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPLT 901
Query 5796 FKMFYKGVITHDVSSAI--NRPQIGVVREFLTRNPAWRKA---------VFISPYNSQNA 5844
F + S+A N VV W A ++PY Q
Sbjct 902 FFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVF 961
Query 5845 ------VASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC------------------ 5880
++ + + V + QG ++ V+F T T H+C
Sbjct 962 RIRAELRKKRLSDVNVERVLNVQGKQFR-VLFLSTVRTRHTCKHKQTPIKKKEQLLEDST 1020
Query 5881 ---------NVNRFNVAITRAKVGILCIMSDRDL 5905
N N AITRA+ + + L
Sbjct 1021 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPIAL 1054
>sp|Q6DFV5|HELZ_MOUSE Probable helicase with zinc finger domain
OS=Mus musculus OX=10090 GN=Helz PE=1 SV=2
Length=1964
Score = 62.4 bits (150), Expect = 2e-07, Method: Composition-based stats.
Identities = 72/394 (18%), Positives = 115/394 (29%), Gaps = 93/394 (24%)
Query 5602 STLQGPPGTGKSHF---AIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5658
+ GP GTGK+ A L RI+ S++A D + L +
Sbjct 664 VLIIGPYGTGKTFTLAQAAKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQAR 723
Query 5659 PARARVECFDKFK------------VNSTLEQY----------------VFCTVNALPET 5690
P RV +++ ++ST + T L +
Sbjct 724 P--LRVYFRNRWVKTVHPVVHQYCLISSTQSTFQMPQKEDILKHRVVVVTLSTSQYLCQL 781
Query 5691 T-----ADIVVFDEISMATNYDLSV-VNARLRAKHYVYIGDPAQLPAPRT--LLTKGTLE 5742
V+ DE + A + + + + V GD QL + L
Sbjct 782 DLEPGFFTHVLLDEAAQAMECETIMPLALATKNTRIVLAGDHMQLSPFVYSEFARERNLH 841
Query 5743 PEYFNSVCRLMKTIGP-DMFLGTCRRCPAEIVDTVSALVYDNKLK------AHKDKSAQC 5795
+ + P + L R I++ S L Y+ KL AHKD
Sbjct 842 VSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPLT 901
Query 5796 FKMFYKGVITHDVSSAI--NRPQIGVVREFLTRNPAWRKA---------VFISPYNSQNA 5844
F + S+A N VV W A ++PY Q
Sbjct 902 FFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVF 961
Query 5845 ------VASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC------------------ 5880
++ + + V + QG ++ V+F T T H+C
Sbjct 962 RIRAELRKKRLSDVNVERVLNVQGKQFR-VLFLSTVRTRHTCKHKQTPIKKKEQLLEDST 1020
Query 5881 ---------NVNRFNVAITRAKVGILCIMSDRDL 5905
N N AITRA+ + + L
Sbjct 1021 EDLDYGFLSNYKLLNTAITRAQSLVAVVGDPVAL 1054
>sp|Q81862|POLN_HEVCH Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 1 (isolate Human/China/HeBei/1987) OX=652674
GN=ORF1 PE=1 SV=1
Length=1693
Score = 61.6 bits (148), Expect = 4e-07, Method: Composition-based stats.
Identities = 23/108 (21%), Positives = 41/108 (38%), Gaps = 11/108 (10%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLH 1116
+VNA+NV + GGG+ A + + S G + + +H
Sbjct 803 LVNASNVDHRPGGGLCHAFYQRYPASFDAASFVMRD-------GAAAYT---LTPRPIIH 852
Query 1117 VVGPNVNKGEDIQLLKSAYEN-FNQHEVLLAPLLSAGIFGADPIHSLR 1163
V P+ + ++L++AY ++ PLL GI+ S
Sbjct 853 AVAPDYRLEHNPKMLEAAYRETCSRLGTAAYPLLGTGIYQVPIGPSFD 900
Score = 38.1 bits (87), Expect = 4.8, Method: Composition-based stats.
Identities = 54/305 (18%), Positives = 92/305 (30%), Gaps = 88/305 (29%)
Query 5597 GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5656
G+ +Y G PG+GKS + + A VD
Sbjct 966 GVVQYQFTAGVPGSGKSR-----------------SITQADVD---------------VV 993
Query 5657 IIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLR 5716
++P R E + ++ F A T VV DE + L + R
Sbjct 994 VVPTR---ELRNAWRRRGFAA---FTPHTAARVTQGRRVVIDEAPSLPPHLLLLHMQRAA 1047
Query 5717 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5776
H +GDP Q+PA ++ E+ V + + P + RCPA++ + +
Sbjct 1048 TVH--LLGDPNQIPA---------IDFEHAGLVPAIRPDLAPTSWWHVTHRCPADVCELI 1096
Query 5777 SALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFI 5836
+++ + + G +K VF
Sbjct 1097 RGAY------PMIQTTSRVLRSLFWGEPAV-----------------------GQKLVFT 1127
Query 5837 SPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR--FNVAITRAKV 5894
+ N + TV +QG+ Y T + +R VA+TR
Sbjct 1128 QAAKAANPGSV--------TVHEAQGATYTETTIIATADARGLIQSSRAHAIVALTRHTE 1179
Query 5895 GILCI 5899
+ I
Sbjct 1180 KCVII 1184
>sp|P33424|POLN_HEVPA Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 1 (isolate Human/Pakistan/Sar-55) OX=33774
GN=ORF1 PE=1 SV=2
Length=1693
Score = 61.2 bits (147), Expect = 4e-07, Method: Composition-based stats.
Identities = 23/108 (21%), Positives = 40/108 (37%), Gaps = 11/108 (10%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLH 1116
+VNA+NV + GGG+ A + + S G + + +H
Sbjct 803 LVNASNVDHRPGGGLCHAFYQRYPASFDAASFVMRD-------GAAAYT---LTPRPIIH 852
Query 1117 VVGPNVNKGEDIQLLKSAYEN-FNQHEVLLAPLLSAGIFGADPIHSLR 1163
V P+ + + L++AY ++ PLL GI+ S
Sbjct 853 AVAPDYRLEHNPKRLEAAYRETCSRLGTAAYPLLGTGIYQVPIGPSFD 900
Score = 38.1 bits (87), Expect = 4.8, Method: Composition-based stats.
Identities = 54/305 (18%), Positives = 92/305 (30%), Gaps = 88/305 (29%)
Query 5597 GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5656
G+ +Y G PG+GKS + + A VD
Sbjct 966 GVVQYQFTAGVPGSGKSR-----------------SITQADVD---------------VV 993
Query 5657 IIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLR 5716
++P R E + ++ F A T VV DE + L + R
Sbjct 994 VVPTR---ELRNAWRRRGFAA---FTPHTAARVTQGRRVVIDEAPSLPPHLLLLHMQRAA 1047
Query 5717 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5776
H +GDP Q+PA ++ E+ V + + P + RCPA++ + +
Sbjct 1048 TVH--LLGDPNQIPA---------IDFEHAGLVPAIRPDLAPTSWWHVTHRCPADVCELI 1096
Query 5777 SALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFI 5836
+++ + + G +K VF
Sbjct 1097 RGAY------PMIQTTSRVLRSLFWGEPAV-----------------------GQKLVFT 1127
Query 5837 SPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR--FNVAITRAKV 5894
+ N + TV +QG+ Y T + +R VA+TR
Sbjct 1128 QAAKAANPGSV--------TVHEAQGATYTETTIIATADARGLIQSSRAHAIVALTRHTE 1179
Query 5895 GILCI 5899
+ I
Sbjct 1180 KCVII 1184
>sp|P29324|POLN_HEVBU Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 1 (isolate Human/Burma) OX=31767 GN=ORF1
PE=1 SV=1
Length=1693
Score = 61.2 bits (147), Expect = 4e-07, Method: Composition-based stats.
Identities = 23/108 (21%), Positives = 40/108 (37%), Gaps = 11/108 (10%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLH 1116
+VNA+NV + GGG+ A + + S G + + +H
Sbjct 803 LVNASNVDHRPGGGLCHAFYQRYPASFDAASFVMRD-------GAAAYT---LTPRPIIH 852
Query 1117 VVGPNVNKGEDIQLLKSAYEN-FNQHEVLLAPLLSAGIFGADPIHSLR 1163
V P+ + + L++AY ++ PLL GI+ S
Sbjct 853 AVAPDYRLEHNPKRLEAAYRETCSRLGTAAYPLLGTGIYQVPIGPSFD 900
>sp|Q6J8G2|POLN_HEVMG Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 3 (isolate Swine/United States/swUS1)
OX=512345 GN=ORF1 PE=3 SV=1
Length=1708
Score = 60.1 bits (144), Expect = 1e-06, Method: Composition-based stats.
Identities = 25/109 (23%), Positives = 46/109 (42%), Gaps = 13/109 (12%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-AKHCL 1115
+VNA+N + GGG+ A + A ++I G L+ + L + +
Sbjct 818 LVNASNPGHRPGGGLCHAFYQRFPEAF--YPTEFIMREG---------LAAYTLTPRPII 866
Query 1116 HVVGPNVNKGEDIQLLKSAYEN-FNQHEVLLAPLLSAGIFGADPIHSLR 1163
H V P+ ++ + L++AY ++ PLL +GI+ S
Sbjct 867 HAVAPDYRVEQNPKRLEAAYRETCSRRGTAAYPLLGSGIYQVPVSLSFD 915
>sp|Q9WC28|POLN_HEVHY Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 1 (isolate Human/India/Hyderabad) OX=512346
GN=ORF1 PE=1 SV=1
Length=1693
Score = 58.9 bits (141), Expect = 2e-06, Method: Composition-based stats.
Identities = 22/108 (20%), Positives = 38/108 (35%), Gaps = 11/108 (10%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLH 1116
+VNA+NV GGG+ A + + G + + +H
Sbjct 803 LVNASNVDHCPGGGLCHAFYQRYPASFDAACFVMRD-------GAAAYT---LTPRPIIH 852
Query 1117 VVGPNVNKGEDIQLLKSAYEN-FNQHEVLLAPLLSAGIFGADPIHSLR 1163
V P+ + + L++AY ++ PLL GI+ S
Sbjct 853 RVAPDYRLEHNPKRLEAAYRETCSRLGTAAYPLLGTGIYQVPIGPSFD 900
>sp|Q9M041|BH140_ARATH Transcription factor bHLH140 OS=Arabidopsis
thaliana OX=3702 GN=BHLH140 PE=3 SV=1
Length=912
Score = 58.5 bits (140), Expect = 2e-06, Method: Composition-based stats.
Identities = 31/121 (26%), Positives = 48/121 (40%), Gaps = 24/121 (20%)
Query 1041 KNADIVEEAKK--VKPTVVVNAANVYLK-HGGGVAGALNKATNNAMQVESDDYIATNGPL 1097
DI + + + V+ NA N LK GGGV A+ KA + E+ + N L
Sbjct 527 FVGDITKLRSEGGLHCNVIANATNWRLKPGGGGVNAAIFKAAGPDL--ETATRVRAN-TL 583
Query 1098 KVGGSCVLSGHNLA--------KHCLHVVGPNVNKGEDIQL----------LKSAYENFN 1139
G + V+ + H +HV+GPN+N L L+ AY +
Sbjct 584 LPGKAVVVPLPSTCPLHNAEGITHVIHVLGPNMNPNRPDNLNNDYTKGCKTLREAYTSLF 643
Query 1140 Q 1140
+
Sbjct 644 E 644
>sp|Q03495|POLN_HEVME Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 2 (isolate Human/Mexico) OX=31768 GN=ORF1
PE=3 SV=1
Length=1691
Score = 58.5 bits (140), Expect = 3e-06, Method: Composition-based stats.
Identities = 36/183 (20%), Positives = 65/183 (36%), Gaps = 19/183 (10%)
Query 1053 KPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-A 1111
+ T +VNA+N + GGG+ A + ++ ++ +G L+ + L
Sbjct 797 ECTWLVNASNAGHRPGGGLCHAFFQRYPDSFDA--TKFVMRDG---------LAAYTLTP 845
Query 1112 KHCLHVVGPNVNKGEDIQLLKSAYEN-FNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVR 1170
+ +H V P+ + + L++AY + PLL AGI+ S R
Sbjct 846 RPIIHAVAPDYRLEHNPKRLEAAYRETCARRGTAAYPLLGAGIYQVPVSLSFDAWERNHR 905
Query 1171 TNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDK 1230
FD+ +L + + E Q I E + S R
Sbjct 906 P------FDELYLTELAARWFESNRPGQPTLNITEDTARAANLALELDSGSEVGRACAGC 959
Query 1231 KIK 1233
K++
Sbjct 960 KVE 962
Score = 37.4 bits (85), Expect = 7.5, Method: Composition-based stats.
Identities = 23/96 (24%), Positives = 39/96 (41%), Gaps = 11/96 (11%)
Query 5681 FCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGT 5740
F A T+ VV DE + L + R + H +GDP Q+PA
Sbjct 1010 FTPHTAARVTSGRRVVIDEAPSLPPHLLLLHMQRAASVH--LLGDPNQIPA--------- 1058
Query 5741 LEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5776
++ E+ + + + P + RCPA++ + V
Sbjct 1059 IDFEHTGLIPAIRPELVPTSWWHVTHRCPADVCELV 1094
>sp|Q04610|POLN_HEVMY Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 1 (isolate Human/Myanmar/HEVNE8L) OX=31769
GN=ORF1 PE=1 SV=1
Length=1693
Score = 57.8 bits (138), Expect = 5e-06, Method: Composition-based stats.
Identities = 22/108 (20%), Positives = 39/108 (36%), Gaps = 11/108 (10%)
Query 1057 VVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLH 1116
+VNA+NV + GGG+ A + + S G + + +H
Sbjct 803 LVNASNVDHRPGGGLCHAFYQRYPASFDAASFVMRD-------GAAAYT---LTPRPIIH 852
Query 1117 VVGPNVNKGEDIQLLKSAYEN-FNQHEVLLAPLLSAGIFGADPIHSLR 1163
V P+ + + L++AY ++ LL GI+ S
Sbjct 853 AVAPDYRLEHNPKRLEAAYRETCSRLGTAAYSLLGTGIYQVPIGPSFD 900
Score = 38.9 bits (89), Expect = 2.5, Method: Composition-based stats.
Identities = 55/305 (18%), Positives = 93/305 (30%), Gaps = 88/305 (29%)
Query 5597 GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5656
G+ +Y G PG+GKS + + A VD
Sbjct 966 GVVQYQFTAGVPGSGKSR-----------------SITQADVD---------------VV 993
Query 5657 IIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLR 5716
++P R E + ++ F A T VV DE + L + R
Sbjct 994 VVPTR---ELRNAWRRRGFAA---FNPHTAARVTQGRRVVIDEAPSLPPHLLLLHMQRAA 1047
Query 5717 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5776
H +GDP Q+PA ++ E+ V + +GP + RCPA++ + +
Sbjct 1048 TVH--LLGDPNQIPA---------IDFEHAGLVPAIRPDLGPTSWWHVTHRCPADVCELI 1096
Query 5777 SALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFI 5836
+++ + + G +K VF
Sbjct 1097 RGAY------PMIQTTSRVLRSLFWGEPAV-----------------------GQKLVFT 1127
Query 5837 SPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR--FNVAITRAKV 5894
+ N + TV +QG+ Y T + +R VA+TR
Sbjct 1128 QAAKAANPGSV--------TVHEAQGATYTETTIIATADARGLIQSSRAHAIVALTRHTE 1179
Query 5895 GILCI 5899
+ I
Sbjct 1180 KFVII 1184
>sp|Q9IVZ9|POLN_HEVCT Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 4 (isolate Human/China/T1) OX=509627
GN=ORF1 PE=3 SV=1
Length=1707
Score = 57.8 bits (138), Expect = 5e-06, Method: Composition-based stats.
Identities = 24/113 (21%), Positives = 47/113 (42%), Gaps = 13/113 (12%)
Query 1053 KPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNL-A 1111
+ T +VNA+N + GGG+ A + + ++I ++G + + L
Sbjct 813 ECTWLVNASNPGHRPGGGLCHAFYQRFPESFDPA--EFIMSDG---------FAAYTLTP 861
Query 1112 KHCLHVVGPNVNKGEDIQLLKSAYEN-FNQHEVLLAPLLSAGIFGADPIHSLR 1163
+ +H V P+ + + L++AY ++ PLL GI+ S
Sbjct 862 RPIIHAVAPDYRVEHNPKRLEAAYRETCSRRGTAAYPLLGVGIYRVPVGLSFD 914
Score = 40.1 bits (92), Expect = 1.2, Method: Composition-based stats.
Identities = 33/186 (18%), Positives = 57/186 (31%), Gaps = 48/186 (26%)
Query 5716 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5775
RA +GDP Q+PA ++ E+ V + + P + RCPA++ +
Sbjct 1059 RASSVHLLGDPNQIPA---------IDFEHAGLVPAIRPELVPTKWWHLTYRCPADVCE- 1108
Query 5776 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVF 5835
+ +S + R F P + VF
Sbjct 1109 ----------------------LIRGAYPKIQTASRVLR------SLFWEEPPVGQNLVF 1140
Query 5836 ISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR--FNVAITRAK 5893
+ N A TV +QG+ + T + +R VA+TR
Sbjct 1141 TQAAKAANPGAI--------TVHEAQGATFTETTIIATADARGLIQSSRAHAIVALTRHT 1192
Query 5894 VGILCI 5899
+ +
Sbjct 1193 EKCVVV 1198
>sp|P18479|POLG_ZYMVC Genome polyprotein OS=Zucchini yellow mosaic
virus (strain California) OX=117128 PE=1 SV=2
Length=3080
Score = 57.8 bits (138), Expect = 5e-06, Method: Composition-based stats.
Identities = 57/274 (21%), Positives = 111/274 (41%), Gaps = 40/274 (15%)
Query 4846 DYYRYNLPTM---CDIRQLLFVVEVVDKY---FDCYDGGCINANQVIVNNLDKSAGFPFN 4899
D+++YN P D + L V+ V + F+ + I + I N+L+ A
Sbjct 2356 DFFKYNKPVTVNQLDHDKFLGAVDGVIRMMCDFEFNECRFITDPEEIYNSLNMKAAIGAQ 2415
Query 4900 KWGKARLYYDSMS-YEDQDALFAYTKR--NVIPTITQMNLKYAISAKNRAR--------- 4947
GK + Y++ + ++ + LF +R N + +LK + + R
Sbjct 2416 YRGKKKEYFEGLDDFDRERLLFQSCERLFNGYKGLWNGSLKAELRPLEKVRANKTRTFTA 2475
Query 4948 ----TVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVEN 5003
T+ G +C N +F++K LK +G +KFYGGW +++++
Sbjct 2476 APIDTLLGAKVCVDDFNNEFYRKNLK-------CPWTVGMTKFYGGWDKLMRSL------ 2522
Query 5004 PHLMGWDYPKCDRAM--PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMC 5061
P GW Y D + ++ + + VL + L N A+++ ++
Sbjct 2523 PD--GWLYCHADGSQFDSSLTPALLNAVLIIRSFYMEDWWVGQEMLENLYAEIVYTPILA 2580
Query 5062 -GGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5094
G+++ K G +SG +T N++ + A
Sbjct 2581 PDGTIFKKFRGNNSGQPSTVVDNTLMVVISIYYA 2614
>sp|P47386|Y140_MYCGE Uncharacterized ATP-dependent helicase MG140
OS=Mycoplasma genitalium (strain ATCC 33530 / DSM 19775
/ NCTC 10195 / G37) OX=243273 GN=MG140 PE=3 SV=1
Length=1113
Score = 55.1 bits (131), Expect = 3e-05, Method: Composition-based stats.
Identities = 51/259 (20%), Positives = 92/259 (36%), Gaps = 50/259 (19%)
Query 5693 DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPE-------- 5744
D VV DE S + RA Y+ GD QL ++ + +
Sbjct 697 DYVVIDEASQVFLERA--IPILFRADKYIIAGDTKQLKPANFFQSRAEYDVDEEFEDGNI 754
Query 5745 ----YFNSVCRLMKTIGPDMFLGTC-RRC-PAEIVDTVSALVYDNKL----KAHKDKSAQ 5794
+ +S+ +K + L R A+++ + +YDN+L KA+ D+
Sbjct 755 EAAVHSSSLLHFLKNRSRILTLLKFHYRSDSADLIAFTNNRIYDNELIFMNKANADQRVF 814
Query 5795 CFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKIL---- 5850
G+ ++ + R + + + T N + I +Q + ++
Sbjct 815 IVHDVIDGIWKNNRNLQEARDVVQRLEQLTTTNDYKKSLGVICFNKNQADLIEYLIDKQN 874
Query 5851 ------------------GLPTQTVDSSQGSEYDYVIFTQTTE--------TAHSCNVNR 5884
GL + +++ QG E D +IF+ + + NR
Sbjct 875 NPLLNEWRERQNDVGEYEGLFVKNIENVQGDERDIIIFSLGYDRSVNSYGPISKQGGENR 934
Query 5885 FNVAITRAKVGILCIMSDR 5903
NVAITRAK I ++R
Sbjct 935 LNVAITRAKQRIELFKTNR 953
>sp|P18478|POLG_WMV2U Genome polyprotein (Fragment) OS=Watermelon
mosaic virus II (isolate USA) OX=148360 PE=1 SV=3
Length=1017
Score = 53.9 bits (128), Expect = 7e-05, Method: Composition-based stats.
Identities = 57/279 (20%), Positives = 112/279 (40%), Gaps = 50/279 (18%)
Query 4846 DYYRYNLPTMCDI-------RQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPF 4898
D+++YN P + + + + V+ ++ F+ + + I +L+ A
Sbjct 291 DFFKYNKPVVLNEVDFNAFEKAVEGVITMMVD-FEFAECLFVTDPDEIYGSLNMKAAVGA 349
Query 4899 NKWGKARLYYDSM-SYEDQDALFAYTKR--NVIPTITQMNLKYAI-------SAKNRART 4948
GK + Y+ M S++ + L+ +R N I +LK + + K R T
Sbjct 350 QYKGKKQDYFSGMDSFDKERLLYLSCERLFNGEKGIWNGSLKAELRPIEKVQANKTRTFT 409
Query 4949 VA------GVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE 5002
A G +C N QF+ LK +G +KFYGGW +++++
Sbjct 410 AAPLDTLLGAKVCVDDFNNQFYSFNLK-------CPWTVGMTKFYGGWDKLMRSLPDGWT 462
Query 5003 NPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVL-SEMVM 5060
H G + D ++ P +L + S+ CC + + + E + L +E+V
Sbjct 463 YCHADGSQF---DSSLTPLLLNAVLSI-------RCCFMED--WWVGREMLENLYAEIVY 510
Query 5061 C-----GGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5094
G+++ K G +SG +T N++ + +
Sbjct 511 TPILAPDGTIFKKFRGNNSGQPSTVVDNTLMVVIAMYYS 549
>sp|Q54PT1|GDAP2_DICDI Protein GDAP2 homolog OS=Dictyostelium
discoideum OX=44689 GN=gdap2 PE=3 SV=1
Length=568
Score = 53.5 bits (127), Expect = 7e-05, Method: Composition-based stats.
Identities = 40/241 (17%), Positives = 80/241 (33%), Gaps = 42/241 (17%)
Query 1027 SFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVE 1086
F ++ + + DI + +V + + L ++ + K + M +
Sbjct 48 QFKIDTEINSRICLWMGDIC----NLNTDTIVYSNSKTLTESDTISDKIFKYGGSEMMND 103
Query 1087 SDDYIATNGPLKVGGSCVLSGHNLA-KHCLHVVGPNVNK---GEDIQLLKSAYENFN--- 1139
I NG + G S + SG NL + +H V P N L S Y +
Sbjct 104 ----IQKNGECRYGESIITSGGNLPSRFVVHTVCPTYNPKYLSAAENALNSCYRSAFHLS 159
Query 1140 ---QHEVLLAPLLSAGIFGADPIHSLRVCVDTVR-----------TNVYLAVF---DKNL 1182
+ + + L + + + + T+R V LA+ D L
Sbjct 160 MDVKSKSISFSTLHSEKRQFPSVGGCHIALRTIRRFLEKPFSKSFEKVILAINTFEDLRL 219
Query 1183 YDKLVSSFL----------EMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKI 1232
Y++++ + ++ K V + E E K I E+ ++ + +D
Sbjct 220 YEQMLPIYFPRNQQELKFSQISLPKDVGDENGEAIVESRKIRIIETPSTIIREPEDYNCF 279
Query 1233 K 1233
Sbjct 280 Y 280
>sp|Q9J942|RDRP_TRVPP Replicase large subunit OS=Tobacco rattle
virus (isolate PpK20) OX=652939 PE=3 SV=2
Length=1707
Score = 53.9 bits (128), Expect = 8e-05, Method: Composition-based stats.
Identities = 61/303 (20%), Positives = 107/303 (35%), Gaps = 54/303 (18%)
Query 5601 YSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEK-ALKYLPIDKCSRIIP 5659
+ + G PG GKS + P +V + AA D L E+ A K P
Sbjct 899 FELVDGVPGCGKSTMIVN--SANPCVDVVL-STGRAATDDLIERFASKGFP-------CK 948
Query 5660 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5719
+ RV+ D F + C +L T D++ FDE MA + AK
Sbjct 949 LKRRVKTVDSF--------LMHCVDGSL---TGDVLHFDEALMAHAGMVYFCAQIAGAKR 997
Query 5720 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5779
+ GD Q+ + + F+S+ + R PA++ ++
Sbjct 998 CICQGDQNQISFK----PRVSQVDLRFSSLVGKFDIVTEKR---ETYRSPADVAAVLNK- 1049
Query 5780 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVV-REFLTRNPAWRKAVFISP 5838
+Y G + ++A + +V +E ++ P + F+
Sbjct 1050 -------------------YYTGDVRTHNATANSMTVRKIVSKEQVSLKPGAQYITFLQS 1090
Query 5839 YNSQ--NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR--FNVAITRAKV 5894
+ N +A + + TV SQG + V+ +T T S R VA++R
Sbjct 1091 EKKELVNLLALRKVAAKVSTVHESQGETFKDVVLVRTKPTDDSIARGREYLIVALSRHTQ 1150
Query 5895 GIL 5897
++
Sbjct 1151 SLV 1153
>sp|P05080|194K_TRVSY Replicase large subunit OS=Tobacco rattle
virus (strain SYM) OX=12298 PE=3 SV=2
Length=1707
Score = 53.9 bits (128), Expect = 8e-05, Method: Composition-based stats.
Identities = 61/303 (20%), Positives = 107/303 (35%), Gaps = 54/303 (18%)
Query 5601 YSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEK-ALKYLPIDKCSRIIP 5659
+ + G PG GKS + P +V + AA D L E+ A K P
Sbjct 899 FELVDGVPGCGKSTMIVN--SANPCVDVVL-STGRAATDDLIERFASKGFP-------CK 948
Query 5660 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5719
+ RV+ D F + C +L T D++ FDE MA + AK
Sbjct 949 LKRRVKTVDSF--------LMHCVDGSL---TGDVLHFDEALMAHAGMVYFCAQIAGAKR 997
Query 5720 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5779
+ GD Q+ + + F+S+ + R PA++ ++
Sbjct 998 CICQGDQNQISFK----PRVSQVDLRFSSLVGKFDIVTEKR---ETYRSPADVAAVLNK- 1049
Query 5780 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVV-REFLTRNPAWRKAVFISP 5838
+Y G + ++A + +V +E ++ P + F+
Sbjct 1050 -------------------YYTGDVRTHNATANSMTVRKIVSKEQVSLKPGAQYITFLQS 1090
Query 5839 YNSQ--NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR--FNVAITRAKV 5894
+ N +A + + TV SQG + V+ +T T S R VA++R
Sbjct 1091 EKKELVNLLALRKVAAKVSTVHESQGETFKDVVLVRTKPTDDSIARGREYLIVALSRHTQ 1150
Query 5895 GIL 5897
++
Sbjct 1151 SLV 1153
>sp|P08411|POLN_SFV Polyprotein P1234 OS=Semliki forest virus
OX=11033 PE=1 SV=2
Length=2432
Score = 53.5 bits (127), Expect = 1e-04, Method: Composition-based stats.
Identities = 35/202 (17%), Positives = 62/202 (31%), Gaps = 34/202 (17%)
Query 1062 NVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPN 1121
N G GV A+ K +A VG + + +H V PN
Sbjct 1360 NARGTVGDGVCRAVAKKWPSAF---------KGAATPVGTIKTVMCGSYP--VIHAVAPN 1408
Query 1122 VNKGEDIQ---LLKSAYENFNQH------EVLLAPLLSAGIFGA------DPIHSLRVCV 1166
+ + + L + Y + PLLS G+F ++ L +
Sbjct 1409 FSATTEAEGDRELAAVYRAVAAEVNRLSLSSVAIPLLSTGVFSGGRDRLQQSLNHLFTAM 1468
Query 1167 DTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRK 1226
D +V + DK+ K+ E + E+ ++V+ + +
Sbjct 1469 DATDADVTIYCRDKSWEKKI--------QEAIDMRTAVELLNDDVELTTDLVRVHPDSSL 1520
Query 1227 QDDKKIKACVEEVTTTLEETKF 1248
K + + E TKF
Sbjct 1521 VGRKGYSTTDGSLYSYFEGTKF 1542
Score = 44.7 bits (104), Expect = 0.046, Method: Composition-based stats.
Identities = 49/259 (19%), Positives = 80/259 (31%), Gaps = 65/259 (25%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG+GKS AI +L H V + + C I+
Sbjct 721 VFGVPGSGKS--AIIKSLVT----------KHDLVTS--------GKKENCQEIV---ND 757
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK-HYVY 5722
V+ + + + +N DI+ DE + L + A ++ + V
Sbjct 758 VKKHRGLDIQAKTVDSIL--LNG-CRRAVDILYVDEAFACHSGTLLALIALVKPRSKVVL 814
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5782
GDP Q + K VC RRC + VS L Y
Sbjct 815 CGDPKQCGFFNMMQLKVNFNHNICTEVCHK----------SISRRCTRPVTAIVSTLHYG 864
Query 5783 NKLKAHKDKSA-------------------QCFKMFYK----GVITHDVSSA-----INR 5814
K++ + CF+ + K H+V +A + R
Sbjct 865 GKMRTTNPCNKPIIIDTTGQTKPKPGDIVLTCFRGWVKQLQLDYRGHEVMTAAASQGLTR 924
Query 5815 PQIGVVREFLTRNPAWRKA 5833
+ VR+ + NP + A
Sbjct 925 KGVYAVRQKVNENPLYAPA 943
>sp|Q89330|POLG_ZYMVR Genome polyprotein OS=Zucchini yellow mosaic
virus (strain Reunion Island) OX=117129 PE=3 SV=1
Length=3083
Score = 53.5 bits (127), Expect = 1e-04, Method: Composition-based stats.
Identities = 58/277 (21%), Positives = 111/277 (40%), Gaps = 40/277 (14%)
Query 4846 DYYRYNLPTMCDIRQLLFVVEVVDKY------FDCYDGGCINANQVIVNNLDKSAGFPFN 4899
D+++YN P + + +E VD F+ + I + I ++L+ A
Sbjct 2359 DFFKYNKPVIVNQLDHDKFLEAVDGVIRMMCDFEFNECRFITDPEEIYSSLNMKAAIGAQ 2418
Query 4900 KWGKARLYYDSM-SYEDQDALFAYTKR--NVIPTITQMNLKYAI-------SAKNRARTV 4949
GK + Y++ + +++ + LF +R N + +LK + + K R T
Sbjct 2419 YRGKKKEYFEGLDNFDMERLLFQSCERLFNGYKGLWNGSLKAELRPLEKVQANKTRTFTA 2478
Query 4950 A------GVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVEN 5003
A G +C N +F+ K LK +G SKFYGGW +++ +
Sbjct 2479 APIDTLLGAKVCVDDFNNEFYSKNLK-------CPWTVGMSKFYGGWDKLMRAL------ 2525
Query 5004 PHLMGWDYPKCDRAM--PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMC 5061
P GW Y D + ++ + + VL + L N A+++ ++
Sbjct 2526 PD--GWLYCHADGSQFDSSLTPALLNAVLIIRSFYMEDWWVGQEMLENLYAEIVYTPILA 2583
Query 5062 -GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVN 5097
G+++ K G +SG +T N++ + A +
Sbjct 2584 PDGTIFKKFRGNNSGQPSTVVDNTLMVVISIYYACIK 2620
>sp|O36979|POLG_ZYMVS Genome polyprotein OS=Zucchini yellow mosaic
virus (strain Singapore) OX=117130 PE=3 SV=2
Length=3083
Score = 53.2 bits (126), Expect = 1e-04, Method: Composition-based stats.
Identities = 58/274 (21%), Positives = 111/274 (41%), Gaps = 40/274 (15%)
Query 4846 DYYRYNLPTM---CDIRQLLFVVEVVDKY---FDCYDGGCINANQVIVNNLDKSAGFPFN 4899
D+++YN P + D + L V V + F+ + I + I ++L+ A
Sbjct 2359 DFFKYNKPVVVNQLDHDKFLGAVNGVIRMMCDFEFNECRFITDPEEIYDSLNMKAAIGAQ 2418
Query 4900 KWGKARLYYDSM-SYEDQDALFAYTKR--NVIPTITQMNLKYAI-------SAKNRARTV 4949
GK + Y++ + +++ + LF +R N + +LK + + K R T
Sbjct 2419 YRGKKKEYFEGLDNFDRERLLFQSCERLFNGHKGLWNGSLKAELRPLEKVQANKTRTFTA 2478
Query 4950 A------GVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVEN 5003
A G +C N +F+ K LK +G +KFYGGW +++ +
Sbjct 2479 APIDTLLGAKVCVDDFNNEFYSKNLK-------CPWTVGMTKFYGGWDKLMREL------ 2525
Query 5004 PHLMGWDYPKCDRAM--PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMC 5061
P GW Y D + ++ + + VL + L N A+++ ++
Sbjct 2526 PD--GWLYCHADGSQFDSSLTPALLNAVLIIRSFYMEDWWVGQEMLENLYAEIVYTPILA 2583
Query 5062 -GGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5094
G+++ K G +SG +T N++ + A
Sbjct 2584 PDGTIFKKFRGNNSGQPSTVVDNTLMVVISIYYA 2617
>sp|P75033|Y153_MYCPN Uncharacterized ATP-dependent helicase MG140
homolog OS=Mycoplasma pneumoniae (strain ATCC 29342 / M129
/ Subtype 1) OX=272634 GN=MPN_153 PE=3 SV=1
Length=1113
Score = 52.4 bits (124), Expect = 2e-04, Method: Composition-based stats.
Identities = 57/269 (21%), Positives = 89/269 (33%), Gaps = 68/269 (25%)
Query 5693 DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTL----EPEYFNS 5748
D VV DE S Y + R Y+ GD QL + E E N
Sbjct 697 DYVVIDEASQV--YLERAIPILYRGAKYIIAGDTKQLKPSNFFQARAEYDVDEEFEDGNV 754
Query 5749 -----VCRLMKTIGPD----MFLGTCRRC-PAEIVDTVSALVYDNKL----KAHKDKSAQ 5794
L+ + L R A ++ + +Y+N+L KA DK
Sbjct 755 EAAVHSTSLLHFLKNRSRILTLLKFHYRSDSANLIAFTNNRIYNNELIFMNKATADKQVF 814
Query 5795 CFKMFYKGVITHDVSSA--------------------------INRPQIGVVREFLTR-- 5826
G+ ++ + N+ Q ++ + +
Sbjct 815 IVHDVIDGIWRNNRNLQEARDVVQRLEQLTQTAEYQKSLGVICFNKNQAELIEYMIDKQN 874
Query 5827 NP---AWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTE-------- 5875
NP WR V N+Q +GL + +++ QG E D +IF+ +
Sbjct 875 NPLLNEWRDRV-----NAQGEY----VGLFVKNIENVQGDERDIIIFSLGYDRSVNSYGP 925
Query 5876 TAHSCNVNRFNVAITRAKVGILCIMSDRD 5904
+ NR NVAITRAK I ++R
Sbjct 926 ISKQGGENRLNVAITRAKQRIELFKTNRA 954
>sp|P89659|RDRP_ORSVC Replicase large subunit OS=Odontoglossum
ringspot virus (isolate Korean Cy) OX=138661 PE=3 SV=2
Length=1612
Score = 51.6 bits (122), Expect = 4e-04, Method: Composition-based stats.
Identities = 68/410 (17%), Positives = 127/410 (31%), Gaps = 64/410 (16%)
Query 5600 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5659
K + + G PG GK+ I+ T E + + C II
Sbjct 820 KVTLVDGVPGCGKT------------KEILETV-------NFDEDLILVPGKEACKMIIK 860
Query 5660 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5719
R + + V + L T + + DE M ++ + A +
Sbjct 861 ---RANKSGHVRATKDNVRTVDSFLMHLKPKTYNKLFIDEGLMLHTGCVNFLIALSHCRE 917
Query 5720 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5779
+ GD Q+P + P++F ++ + + L RCPA++ +++
Sbjct 918 AMVFGDTEQIPFINRVANFPY--PKHFATLVYDHREV---RRLSL--RCPADVTHFMNSK 970
Query 5780 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5839
YD K+ D +G + P+ ++ + KA
Sbjct 971 -YDGKVLCTNDVIRSVDAEVVRGK-------GVFNPKSKPLKGKIITFTQSDKAEL---- 1018
Query 5840 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCI 5899
+ G TV QG ++ V + T T I+++ +L
Sbjct 1019 KERGYEEVSTFG-EINTVHEIQGETFEDVSVVRLTPTPLEL--------ISKSSPHVLVA 1069
Query 5900 MSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK 5959
++ ++ S+ + V+ D KV G+ L V + FK
Sbjct 1070 LTRHT--KSFKYYSVVLDPLVKVCSDLSKVSDFILDMYKVDAGI-----LXQLQVGSIFK 1122
Query 5960 TEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVR 6009
E L V IS M F + + G + + ++R
Sbjct 1123 GENLFV-------PCPKSGYISDMQFYYDTLLPGNSTILNEYDAVTMNLR 1165
>sp|P69514|RDRP_CGMVS Replicase large subunit OS=Cucumber green
mottle mosaic virus (strain watermelon SH) OX=12236 PE=3 SV=1
Length=1648
Score = 50.5 bits (119), Expect = 8e-04, Method: Composition-based stats.
Identities = 51/301 (17%), Positives = 96/301 (32%), Gaps = 52/301 (17%)
Query 5601 YSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPA 5660
+ + G PG GK+ A +A +V T A + +A +
Sbjct 858 ITLVDGVPGCGKT--AEIIARVNWKTDLVLT-PGREAAAMIRRRACALHKSP-----VAT 909
Query 5661 RARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHY 5720
V FD F +N + D V DE M L+ K
Sbjct 910 NDNVRTFDSFVMNRKI-------------FKFDAVYVDEGLMVHTGLLNFALKISGCKKA 956
Query 5721 VYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALV 5780
GD Q+P ++ +Y + L+ ++ RCP ++ ++ +
Sbjct 957 FVFGDAKQIPFINRVMN-----FDYPKELRTLIVDNVERRYVT--HRCPRDVTSFLNTI- 1008
Query 5781 YDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVR-EFLTRNPAWRKAVFISPY 5839
+K A + + + I RP++ ++ + +T + ++++ S Y
Sbjct 1009 -------YKAAVATTSPVVHSVKAIKVSGAGILRPELTKIKGKIITFTQSDKQSLIKSGY 1061
Query 5840 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVN---RFNVAITRAKVGI 5896
N TV QG ++ + T T VA+TR +
Sbjct 1062 N------------DVNTVHEIQGETFEETAVVRATPTPIGLIARDSPHVLVALTRHTKAM 1109
Query 5897 L 5897
+
Sbjct 1110 V 1110
>sp|Q01901|POLG_PRSVH Genome polyprotein OS=Papaya ringspot virus
(strain P / mutant HA) OX=31731 PE=3 SV=2
Length=3344
Score = 50.1 bits (118), Expect = 0.001, Method: Composition-based stats.
Identities = 67/364 (18%), Positives = 130/364 (36%), Gaps = 46/364 (13%)
Query 4873 DCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYT-------KR 4925
+C + I ++VI+ L+ A GK R Y++ + E + AL + +
Sbjct 2624 ECPELEYITDSEVIIQALNMDAAVGALYTGKKRKYFEGSTVEHRQALVRKSCERLYEGRM 2683
Query 4926 NVIPTITQMNLKYA---ISAKNRARTVA------GVSICSTMTNRQFHQKLLKSIAATRG 4976
V + L+ A ++ K R+ T A G +C N F+ K ++
Sbjct 2684 GVWNGSLKAELRPAEKVLAKKTRSFTAAPLDTLLGAKVCVDDFNNWFYSKNME------- 2736
Query 4977 ATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHT 5035
+G +KFY GW LK G + D ++ P +L + S+ L
Sbjct 2737 CPWTVGMTKFYKGWDEFLKKFPDGWVYCDADGSQF---DSSLTPYLLNAVLSIRLWAMED 2793
Query 5036 TCCSLSHRFYRLANECAQVLSEMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5094
L N ++ ++ G++ K G +SG +T N++ + A
Sbjct 2794 ----WDIGEQMLKNLYGEITYTPILTPDGTIVKKFKGNNSGQPSTVVDNTLMVLITMYYA 2849
Query 5095 NVNALLSTDGNK------IADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHF--- 5145
A T + I + H +E + + + Y + ++H
Sbjct 2850 LRKAGYDTKTQEDMCVFYINGDDLCIAIHPDHEHVLDSFSSSFAELGLKYDFAQRHRNKQ 2909
Query 5146 SMMILSDDAVV---CFNSTYASQGLVASIKNFKSVL--YYQNNVFMSEAKCWTETDLTKG 5200
++ +S ++ + + +VA ++ KS L + + + + W DLT
Sbjct 2910 NLWFMSHRGILIDDIYIPKLEPERIVAILEWDKSKLPEHRLEAITAAMIESWGYGDLTHQ 2969
Query 5201 PHEF 5204
F
Sbjct 2970 IRRF 2973
>sp|Q5UQ92|YR530_MIMIV Uncharacterized protein R530 OS=Acanthamoeba
polyphaga mimivirus OX=212035 GN=MIMI_R530 PE=4 SV=1
Length=494
Score = 48.9 bits (115), Expect = 0.002, Method: Composition-based stats.
Identities = 31/146 (21%), Positives = 60/146 (41%), Gaps = 16/146 (11%)
Query 5600 KYSTLQGPPGTGKSHFAIGLALYYPSARIV----YTACSHAAVDALCEKALKYLPIDKCS 5655
K L G G+GK++ + + ++ Y A +H A+ L ++ I+
Sbjct 23 KIFYLIGFAGSGKTYTISKITKKFLVDELIENIYYCAPTHKALKVL--ESYIKSNINASD 80
Query 5656 RIIPARAR---VECFDKFKV---NSTLEQYVFCTVNA--LPETTADIVVFDEISMATNYD 5707
+ + + + + +FK T + T + L + ++VV DE SM +
Sbjct 81 KDLSNKIKFMTIHKLLEFKPIIQTETGSKVFKSTKESKFLKNISKNLVVIDECSMISQEM 140
Query 5708 LSVVNARLR--AKHYVYIGDPAQLPA 5731
+ +N + +Y+GDP QLP
Sbjct 141 VDELNKYINLYPIKIIYMGDPKQLPP 166
>sp|Q89AB2|RECD_BUCBP RecBCD enzyme subunit RecD OS=Buchnera aphidicola
subsp. Baizongia pistaciae (strain Bp) OX=224915 GN=recD
PE=3 SV=1
Length=618
Score = 48.1 bits (113), Expect = 0.003, Method: Composition-based stats.
Identities = 32/160 (20%), Positives = 64/160 (40%), Gaps = 16/160 (10%)
Query 5586 FSSNVANYQKVGM-----QKYSTLQGPPGTGKSHFAIGLALYYPSAR-----IVYTACSH 5635
F++N+ + QK+ + + + G PGTGK+ + + L I TA +
Sbjct 149 FNTNIDDTQKLAIILSIINNITFIIGGPGTGKTTIILKILLVLIRLHKKKINIKLTALTG 208
Query 5636 AAVDALCEKAL---KYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTA 5692
A + L E K L + + + I + + + C N L
Sbjct 209 KAANRLSESIHENIKKLNLTEHEKNIFNQKTTTLHNLLDLKPNKSFNYSCCKNKL--YNL 266
Query 5693 DIVVFDEISMATNYDLSVVNARL-RAKHYVYIGDPAQLPA 5731
++++ DE SM + + + + + +++GD QLP+
Sbjct 267 NLLIIDEASMIDITIMDKLISSIPKTTKIIFLGDYNQLPS 306
>sp|Q9YRB3|RDRP_NCBVS Methyltransferase/helicase/RNA-directed
RNA polymerase OS=Nudaurelia capensis beta virus (isolate Pine
emperor moth/South Africa) OX=652108 PE=3 SV=1
Length=1925
Score = 48.5 bits (114), Expect = 0.003, Method: Composition-based stats.
Identities = 36/178 (20%), Positives = 57/178 (32%), Gaps = 43/178 (24%)
Query 5606 GPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVE 5665
GPPG+GKS A ++Y A + DAL E S + P+R
Sbjct 566 GPPGSGKSRAA-KPRFADLQGGVLYCAPTRTLRDALDE-----------SVVHPSRVCTY 613
Query 5666 CFDKFKVNSTLEQYVFCTVNALPETT-------ADIVVFDEISMATNYDLSVVNARLRAK 5718
NAL D++V DE + ++ +
Sbjct 614 ------------------HNALHVAAKESGNRPFDVIVIDEAETTPACYVGTMHHASPSS 655
Query 5719 HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5776
V +GDP Q+ K L+P ++ T RCP ++++
Sbjct 656 RIVCLGDPHQIGYIDFSDRKDDLKP------FSIIAAECRTRRFNTTYRCPQDVLNLP 707
>sp|P20127|POLR_OYMV RNA replicase polyprotein OS=Ononis yellow
mosaic virus OX=12153 PE=3 SV=1
Length=1776
Score = 48.5 bits (114), Expect = 0.004, Method: Composition-based stats.
Identities = 58/299 (19%), Positives = 93/299 (31%), Gaps = 67/299 (22%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G PG GKSH P +++ T A ++ + + R
Sbjct 897 IAGFPGCGKSH---------PIQKLLQTP------------AFRHFRL----SVPTNELR 931
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNAR-LRAKHYVY 5722
E + E + CT +++I+V DEI L ++ + +
Sbjct 932 SEWKRDLNLPE-SEVWRLCTWETALFKSSNILVVDEIYKLPRGYLDLILLADPSIQLVIM 990
Query 5723 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5782
+GDP Q + + RL K I D + RCP + D ++
Sbjct 991 LGDPLQ--GEYHSSHPSSSNSRLESETTRLSKYI--DCYCWWTYRCPKAVADLFGVKTFN 1046
Query 5783 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5842
+ +G I +S N P +V T N
Sbjct 1047 SN----------------EGFIRAVLSHPPNLP--NLVNSIATANTMQS----------- 1077
Query 5843 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMS 5901
LG T+ SSQG Y + + VA+TR++ GI I S
Sbjct 1078 -------LGHHALTISSSQGMTYSDPVTVLLDRHSLLITPQTALVALTRSRSGIYFIGS 1129
>sp|Q9QBU0|RDRP_PMTVS Replicase large subunit OS=Potato mop-top
virus (isolate Potato/Sweden/Sw) OX=652839 GN=rep PE=3 SV=3
Length=1812
Score = 48.5 bits (114), Expect = 0.004, Method: Composition-based stats.
Identities = 56/310 (18%), Positives = 100/310 (32%), Gaps = 60/310 (19%)
Query 5600 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5659
+ + + G PG GKS + + A + V T AA + L E+
Sbjct 1008 RITLVDGVPGCGKSTYVVKEANL--VNQYVVTIGREAA-EDLRERFKSERNATATQL--- 1061
Query 5660 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5719
RV D + +N T + A+++ FDE MA + L A+
Sbjct 1062 --KRVRTVDSYLLNDTQSR-------------ANVLHFDEALMAHAGMVYFCADDLSARS 1106
Query 5720 YVYIGDPAQLPAPRTL--LTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVS 5777
+ GD Q+P + +T + E N V + + R P ++ ++
Sbjct 1107 VICQGDSQQIPFINRVESITLRYSKLEIDNVVEKRLT-----------YRSPLDVASYLT 1155
Query 5778 AL-VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFI 5836
Y + + + K V I + P ++
Sbjct 1156 KKNFYGTSVVTSANPLVRSLKT---------VGPRDGMTSIYSI-------PKIPGTQYL 1199
Query 5837 SPYNSQNAVASKILG---LPTQTVDSSQGSEYDYVIFTQTTETAHSC------NVNRFNV 5887
+ S+ + LG TV SQG YD V+ + T + + V
Sbjct 1200 TFLQSEKEEMRQYLGRGNWNVNTVHESQGKTYDNVVLCRLKATDNEIYPGGRNSSPYMVV 1259
Query 5888 AITRAKVGIL 5897
+TR + ++
Sbjct 1260 GVTRHRRSLV 1269
>sp|O56075|POLG_PEMVM Genome polyprotein OS=Peanut mottle virus
(strain M) OX=103926 PE=3 SV=1
Length=3099
Score = 48.1 bits (113), Expect = 0.004, Method: Composition-based stats.
Identities = 35/224 (16%), Positives = 83/224 (37%), Gaps = 32/224 (14%)
Query 4880 INANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQM----- 4934
+ + I+++L+ A GK + Y++S+S ++ + + + +M
Sbjct 2415 VTDEEAILDSLNMKAAVGALYKGKKKEYFESLSEPEKHHIVQASCERL--FYGEMGVWNG 2472
Query 4935 NLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYG 4988
+LK + K + + + + K R +G +KFYG
Sbjct 2473 SLKAELRPKEKVALNKTRTFTAAPIDTLLGGKCCVDDFNNRFYSLNIEGPWTVGMTKFYG 2532
Query 4989 GWHNMLKTVYSDVENPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHTTCCSLSHRFYRL 5047
GW +++ + H G + D ++ P +L + ++ L + +
Sbjct 2533 GWDKLMRKLPDGWRYCHADGSQF---DSSLTPFLLNAVLAVRLMFMED---------WWV 2580
Query 5048 ANECAQ-VLSEMVMC-----GGSLYVKPGGTSSGDATTAYANSV 5085
+ + +E++ G++ K G +SG +T N++
Sbjct 2581 GEQMLRNFYTEIIYTPILTPDGTIVKKFKGNNSGQPSTVVDNTL 2624
>sp|Q67724|RDRP_HASV Methyltransferase/helicase/RNA-directed RNA
polymerase OS=Helicoverpa armigera stunt virus OX=37206 PE=2
SV=1
Length=1704
Score = 47.8 bits (112), Expect = 0.005, Method: Composition-based stats.
Identities = 54/285 (19%), Positives = 98/285 (34%), Gaps = 46/285 (16%)
Query 5597 GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5656
G++ Y +GPPG+GK+ I AL + +Y A + +A+ + K +
Sbjct 603 GLEMY---EGPPGSGKTGTLIA-ALEAAGGKALYVAPTRELREAMDRRI-KPPSASRTQH 657
Query 5657 IIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLR 5716
+ A R +T E F T VV DE M +++V+A
Sbjct 658 VALAILR---------RATAEGAPFAT-----------VVIDECFMFPLVYVAIVHALSP 697
Query 5717 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPD---MFLGTCRRCPAEIV 5773
+ V +GD Q+ G ++ + ++ L++ + +RCPA++V
Sbjct 698 SSRIVLVGDVHQI---------GFIDFQGTSANMPLVRDVVKQCRRRTFNQTKRCPADVV 748
Query 5774 DTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKA 5833
T L ++ C I+H N + ++ +
Sbjct 749 ATTFFQ----SLYPGCTTTSGCV-----ASISHVAPDYRNSQAQTLCFTQEEKSRHGAEG 799
Query 5834 VFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAH 5878
AS IL T + +E +++ T T H
Sbjct 800 AMTVHEAQGRTFASVILHYNGSTAEQKLLAEKSHLLVGITRHTNH 844
>sp|Q84133|RDRP_ORSVS Replicase large subunit OS=Odontoglossum
ringspot virus (isolate Singapore 1) OX=138662 PE=3 SV=2
Length=1612
Score = 47.8 bits (112), Expect = 0.005, Method: Composition-based stats.
Identities = 69/412 (17%), Positives = 127/412 (31%), Gaps = 64/412 (16%)
Query 5598 MQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRI 5657
M K + + G PG GK+ + + + A C+ +K R
Sbjct 818 MPKVTLVDGVPGCGKTKEILETVNFDED---LILVPGKEA----CKMIIKRANKSGHVR- 869
Query 5658 IPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRA 5717
R V D F ++ + Y + + DE M ++ + A
Sbjct 870 -ATRDNVRTVDSFLMHLKPKTY-------------NKLFIDEGLMLHTGCVNFLVALSHC 915
Query 5718 KHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVS 5777
+ + GD Q+P + P++F C + + L RCPA++ ++
Sbjct 916 REAMVFGDAEQIPFINRVANFPY--PKHFRYTCLYHREV---RRLSL--RCPADVTHFMN 968
Query 5778 ALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFIS 5837
+ YD K+ D +G + P+ ++ + KA
Sbjct 969 SK-YDGKVLCTNDVIRSVDAEVVRGK-------GVFNPKSKPLKGKIITFTQSDKAEL-- 1018
Query 5838 PYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGIL 5897
+ G TV QG ++ V + T T I+++ +L
Sbjct 1019 --KERGYEEVSTFG-EINTVHEIQGETFEDVSVVRLTPTPLEL--------ISKSSPHVL 1067
Query 5898 CIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTK 5957
++ ++ S+ + V+ D KV G+ L V +
Sbjct 1068 VALTRHT--KSFKYYSVVLDPLVKVWSDLSKVSDFILDMYKVDAGI-----LXQLQVGSI 1120
Query 5958 FKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVR 6009
FK E L V IS M + V G + + ++R
Sbjct 1121 FKGENLFV-------PCPKSGYISDMQTYYDTLVPGNSTILNEYDAVTMNLR 1165
>sp|Q01681|POLG_PPVEA Genome polyprotein (Fragment) OS=Plum pox
potyvirus (strain El amar) OX=31738 PE=2 SV=1
Length=1518
Score = 47.8 bits (112), Expect = 0.006, Method: Composition-based stats.
Identities = 58/348 (17%), Positives = 119/348 (34%), Gaps = 37/348 (11%)
Query 4837 DGNAAISDYDYYRYNLP-TMCDIRQLLFVVEVV------DKYFDCYDGGCINANQVIVNN 4889
+ +A + D Y ++ D Q V+VV + +C + + I +
Sbjct 733 NKDAYVKDLMKYSKSIVVGAVDCEQFERAVDVVISMLISKGFSEC---SYVTDPEEIFSA 789
Query 4890 LDKSAGFPFNKWGKARLYYDSMSYEDQDALF-AYTKRNVI--PTITQMNLKYAISAKNRA 4946
L+ A GK R Y+ S +++ A KR + + +LK + K +
Sbjct 790 LNMKAAVGALYSGKKRDYFKDTSELEKEEFVRASCKRLFMGKKGVWNGSLKAELRPKEKV 849
Query 4947 RTVAGVSICSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKTVYSD 5000
S + + K+ + +G +KF GGW +L+ +
Sbjct 850 EANKTRSFTAAPIDTLLGGKVCVDDFNNQFYSLNLHCPWSVGMTKFRGGWDKLLRALPDG 909
Query 5001 VENPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMV 5059
G + D ++ P ++ + ++ LA L+N +++ +
Sbjct 910 WIYCDADGSQF---DSSLSPYLINAVLNIRLA----FMEEWDIGEQMLSNLYTEIVYTPI 962
Query 5060 MC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRN---- 5114
G++ K G +SG +T N++ I + + D ++ +Y N
Sbjct 963 ATPDGTIVKKFKGNNSGQPSTVVDNTLMVILAMTYSLLKLGYHPDTHECICRYFVNGDDL 1022
Query 5115 --LQHRLYECLYRNRDVDTDFVNEFYAYLRK---HFSMMILSDDAVVC 5157
H YE +Y + Y + K + +S ++C
Sbjct 1023 VLAVHPAYESIYDELQHHFSQLGLNYTFTTKTENKEDLWFMSHKGIMC 1070
>sp|P09814|POLG_TVMV Genome polyprotein OS=Tobacco vein mottling
virus OX=12228 PE=1 SV=2
Length=3023
Score = 47.4 bits (111), Expect = 0.007, Method: Composition-based stats.
Identities = 52/296 (18%), Positives = 99/296 (33%), Gaps = 38/296 (13%)
Query 4837 DGNAAISDYDYYRYNLP-TMCDIRQLLFVVEVVDKYFDCY---DGGCINANQVIVNNLDK 4892
+ A I D Y + D ++V+ + + + + Q I N L+
Sbjct 2307 NKEAYIKDIMKYSKQIVVGSVDCDTFESSLKVLSRKMKEWGFENLEYVTDEQTIKNALNM 2366
Query 4893 SAGFPFNKWGKARLYYDSMSYEDQDALFAYT----------------KRNVIPTITQMNL 4936
A GK + Y++ +S + L + K + P +
Sbjct 2367 DAAVGALYSGKKKQYFEDLSDDAVANLVQKSCLRLFKNKLGVWNGSLKAELRPFEKLIEN 2426
Query 4937 KYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKT 4996
K T+ G +C N F+ K + +G +KFYGGW+ +L
Sbjct 2427 KTRTFTAAPIETLLGGKVCVDDFNNHFYSKHI-------QCPWSVGMTKFYGGWNELLGK 2479
Query 4997 VYSDVENPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVL 5055
+ G + D ++ P ++ VL + ++ L N +++
Sbjct 2480 LPDGWVYCDADGSQF---DSSLSPYLINA----VLRLRLSSMEEWDVGQKMLQNLYTEIV 2532
Query 5056 SEMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADK 5110
+ G++ K G +SG +T N++ + A + L D N D
Sbjct 2533 YTPISTPDGTIVKKFKGNNSGQPSTVVDNTLMVVLAMYYA--LSKLGVDINSQEDV 2586
>sp|P17766|POLG_PPVNA Genome polyprotein OS=Plum pox potyvirus
(isolate NAT) OX=12213 PE=3 SV=1
Length=3125
Score = 46.6 bits (109), Expect = 0.011, Method: Composition-based stats.
Identities = 63/357 (18%), Positives = 127/357 (36%), Gaps = 40/357 (11%)
Query 4837 DGNAAISDYDYYRYNLP---TMCDIRQLLFVVEVV-----DKYFDCYDGGCINANQVIVN 4888
+ +A + D +Y+ P D Q V+VV K F+ + + I +
Sbjct 2357 NKDAYVKDLM--KYSKPIVVGAVDCDQFERAVDVVISMLISKGFE--ECNYVTDPDDIFS 2412
Query 4889 NLDKSAGFPFNKWGKARLYYDSMSYEDQDALF-AYTKRNVI--PTITQMNLKYAISAKNR 4945
L+ A GK R Y++++S +D+++ A KR + + +LK + K +
Sbjct 2413 ALNMKAAVGALYSGKKRDYFENVSDQDKESFVRASCKRLFMGKKGVWNGSLKAELRPKEK 2472
Query 4946 ARTVAGVSICSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKTVYS 4999
S + + K+ + +G +KF GGW +LK +
Sbjct 2473 VEANKTRSFTAAPIDTLLGGKVCVDDFNNQFYSLNLHCPWSVGMTKFRGGWDKLLKALPE 2532
Query 5000 DVENPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEM 5058
G + D ++ P ++ + ++ LA L+N +++
Sbjct 2533 GWIYCDADGSQF---DSSLSPYLINAVLNIRLA----FMEEWDIGEQMLSNLYTEIVYTP 2585
Query 5059 VMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRN--- 5114
+ G++ K G +SG +T N++ I + + D + +Y N
Sbjct 2586 IATPDGTIVKKFKGNNSGQPSTVVDNTLMVILAMTYSLLKLGHHPDTHDCICRYFVNGDD 2645
Query 5115 ---LQHRLYECLYRNRDVDTDFVNEFYAYLRK---HFSMMILSDDAVVCFNSTYASQ 5165
H YE +Y + Y + K + +S V+ ++ Y +
Sbjct 2646 LVLAVHPAYESIYDELQEHFSQLGLNYTFTTKTENKEELWFMSHKGVL-YDDMYIPK 2701
>sp|Q90069|POLG_SBMVG Genome polyprotein OS=Soybean mosaic virus
(strain G2) OX=103931 PE=3 SV=1
Length=3066
Score = 46.6 bits (109), Expect = 0.014, Method: Composition-based stats.
Identities = 47/279 (17%), Positives = 100/279 (36%), Gaps = 28/279 (10%)
Query 4828 ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF-----DCYDGGCINA 4882
K FF + +++ D+ + + ++ ++ + + + + YD + A
Sbjct 2352 AFKRGFFKYNKPVVLNEVDFQSFER-AVAGVKLMMMEFDFKECVYVTDPDEIYDSLNMKA 2410
Query 4883 NQVIVNNLDKSAGF--PFNKWGKARLYY---DSMSYEDQDALFAYTKRNVIPTITQMNLK 4937
V K + + + K RL Y + + Y ++ K + P K
Sbjct 2411 A-VGAQYKGKKQDYFSGMDSFDKERLLYLSCERLFYGEKGVWNGSLKAELRPIEKVQANK 2469
Query 4938 YAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTV 4997
T+ G +C N QF+ L +G +KFY GW +++++
Sbjct 2470 TRTFTAAPIDTLLGAKVCVDDFNNQFYSLNLT-------CPWTVGMTKFYRGWDKLMRSL 2522
Query 4998 YSDVENPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLS 5056
H G + D ++ P +L VL + L N A+++
Sbjct 2523 PDGWVYCHADGSQF---DSSLTPLLLNA----VLDVRSFFMEDWWVGREMLENLYAEIVY 2575
Query 5057 EMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5094
++ G+++ K G +SG +T N++ + +
Sbjct 2576 TPILAPDGTIFKKFRGNNSGQPSTVVDNTLMVVIALYYS 2614
>sp|Q05983|RDRP_RBDVR Methyltransferase/helicase/RNA-directed
RNA polymerase OS=Raspberry bushy dwarf virus (isolate Malling
Jewel raspberry/R15) OX=652675 PE=3 SV=1
Length=1694
Score = 46.2 bits (108), Expect = 0.016, Method: Composition-based stats.
Identities = 43/267 (16%), Positives = 86/267 (32%), Gaps = 33/267 (12%)
Query 5691 TADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC 5750
+ D + DE ++ L + + GD Q+P L P +NSV
Sbjct 917 SCDELFIDEYGLSHPGILLLAIHISGIRKVTLFGDSEQIPFCNRLADF----PLKYNSVE 972
Query 5751 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSS 5810
+ ++ T RCP +I ++ + +K + K + +
Sbjct 973 DVGLNFDREIR-STTYRCPQDITLSLQKMYKTKPIKTVSTVESSITIKPIKSEFEIPLPN 1031
Query 5811 AINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIF 5870
A + P + + + + A + + +TV ++QG Y V++
Sbjct 1032 AFDGPVLY-----ICMTKHDESLLKL-------RWAKENISSEVRTVHAAQGLSYKNVVY 1079
Query 5871 TQTTETAHSCNVNR----FNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQA 5926
+ T T + R VAI+R I + D F+ + +
Sbjct 1080 FRLTRTDNDLYTKRKLPYHLVAISRHTDKI--VYCTTKPEDSSDFSLSALKNTIKTS--- 1134
Query 5927 ENVTGLFKDCSKVITGLHPTQAPTHLS 5953
+D ++ +G + A S
Sbjct 1135 -------RDLTQEASGSESSYAVVFES 1154
>sp|P13529|POLG_PPVD Genome polyprotein OS=Plum pox potyvirus
(strain D) OX=12212 PE=1 SV=2
Length=3141
Score = 45.8 bits (107), Expect = 0.020, Method: Composition-based stats.
Identities = 62/357 (17%), Positives = 126/357 (35%), Gaps = 40/357 (11%)
Query 4837 DGNAAISDYDYYRYNLP---TMCDIRQLLFVVEVV-----DKYFDCYDGGCINANQVIVN 4888
+ +A + D +Y+ P D Q V+VV K F+ + + I +
Sbjct 2358 NKDAYVKDLM--KYSKPIVVGAVDCDQFERAVDVVISMLISKGFE--ECNYVTDPDDIFS 2413
Query 4889 NLDKSAGFPFNKWGKARLYYDSMSYEDQDALF-AYTKRNVI--PTITQMNLKYAISAKNR 4945
L+ A GK R Y+ ++S +D+++ A KR + + +LK + K +
Sbjct 2414 ALNMKAAVGALYSGKKRDYFKNVSDQDKESFVRASCKRLFMGKKGVWNGSLKAELRPKEK 2473
Query 4946 ARTVAGVSICSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKTVYS 4999
S + + K+ + +G +KF GGW +L+ +
Sbjct 2474 VEANKTRSFTAAPIDTLLGGKVCVDDFNNQFYSLNLHCPWSVGMTKFRGGWDKLLRALPE 2533
Query 5000 DVENPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEM 5058
G + D ++ P ++ + ++ LA L+N +++
Sbjct 2534 GWIYCDADGSQF---DSSLSPYLINAVLNIRLA----FMEEWDIGEQMLSNLYTEIVYTP 2586
Query 5059 VMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRN--- 5114
+ G++ K G +SG +T N++ I + + D + +Y N
Sbjct 2587 IATPDGTIVKKFKGNNSGQPSTVVDNTLMVILAMTYSLLKLGYHPDTHDCICRYFVNGDD 2646
Query 5115 ---LQHRLYECLYRNRDVDTDFVNEFYAYLRK---HFSMMILSDDAVVCFNSTYASQ 5165
H YE +Y + Y + K + +S V+ ++ Y +
Sbjct 2647 LVLAVHPAYESIYDELQEHFSQLGLNYTFATKTENKEELWFMSHKGVL-YDDMYIPK 2702
>sp|P17767|POLG_PPVRA Genome polyprotein OS=Plum pox potyvirus
(strain Rankovic) OX=12214 PE=2 SV=2
Length=3140
Score = 45.8 bits (107), Expect = 0.022, Method: Composition-based stats.
Identities = 62/357 (17%), Positives = 126/357 (35%), Gaps = 40/357 (11%)
Query 4837 DGNAAISDYDYYRYNLP---TMCDIRQLLFVVEVV-----DKYFDCYDGGCINANQVIVN 4888
+ +A + D +Y+ P D Q V+VV K F+ + + I +
Sbjct 2357 NKDAYVKDLM--KYSKPIVVGAVDCDQFERAVDVVISMLISKGFE--ECNYVTDPDDIFS 2412
Query 4889 NLDKSAGFPFNKWGKARLYYDSMSYEDQDALF-AYTKRNVI--PTITQMNLKYAISAKNR 4945
L+ A GK R Y+ ++S +D+++ A KR + + +LK + K +
Sbjct 2413 ALNMKAAVGALYSGKKRDYFKNVSDQDKESFVRASCKRLFMGKKGVWNGSLKAELRPKEK 2472
Query 4946 ARTVAGVSICSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKTVYS 4999
S + + K+ + +G +KF GGW +L+ +
Sbjct 2473 VEANKTRSFTAAPIDTLLGGKVCVDDFNNQFYSLNLHCPWSVGMTKFRGGWDKLLRALPE 2532
Query 5000 DVENPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEM 5058
G + D ++ P ++ + ++ LA L+N +++
Sbjct 2533 GWIYCDADGSQF---DSSLSPYLINAVLNIRLA----FMEEWDIGEQMLSNLYTEIVYTP 2585
Query 5059 VMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRN--- 5114
+ G++ K G +SG +T N++ I + + D + +Y N
Sbjct 2586 IATPDGTIVKKFKGNNSGQPSTVVDNTLMVILAMTYSLLKLGYHPDTHDCICRYFVNGDD 2645
Query 5115 ---LQHRLYECLYRNRDVDTDFVNEFYAYLRK---HFSMMILSDDAVVCFNSTYASQ 5165
H YE +Y + Y + K + +S V+ ++ Y +
Sbjct 2646 LVLAVHPAYESIYDELQEHFSQLGLNYTFATKTENKEELWFMSHKGVL-YDDMYIPK 2701
>sp|Q5GS59|RLME_WOLTR Ribosomal RNA large subunit methyltransferase
E OS=Wolbachia sp. subsp. Brugia malayi (strain TRS) OX=292805
GN=rlmE PE=3 SV=1
Length=216
Score = 43.9 bits (102), Expect = 0.023, Method: Composition-based stats.
Identities = 34/152 (22%), Positives = 58/152 (38%), Gaps = 14/152 (9%)
Query 6873 DKGVAPG--TAVLRQWLPTGTLLVDSDLNDFVSDADSTLIG-DCATVHT------ANKWD 6923
D G +PG + V Q G +V D+ + + I D + T K+D
Sbjct 65 DLGASPGGWSQVASQ---KGVKVVAIDIKPVNTISGVKYIQYDINELETLRERFKDQKFD 121
Query 6924 LIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLY-KLM 6982
+I+SDM + ++ F + L GG +KI + + D Y +L
Sbjct 122 VILSDMAPESCGLKSLDHIRIMLLCEAALNFAKHFLNYGGKFVVKIFQGESDKDFYNELK 181
Query 6983 GHFAWWTAFVTNVNAS-SSEAFLIGCNYLGKP 7013
F F + S S+E +L+G ++
Sbjct 182 KMFKIVKYFKPKSSRSESTEMYLVGLGFISNS 213
>sp|P17765|POLG_BYMV Genome polyprotein OS=Bean yellow mosaic
virus OX=12197 PE=3 SV=2
Length=3056
Score = 45.1 bits (105), Expect = 0.035, Method: Composition-based stats.
Identities = 40/231 (17%), Positives = 80/231 (35%), Gaps = 20/231 (9%)
Query 4886 IVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPT---ITQMNLKYAISA 4942
I++ L+ A GK + ++ +S E D + + + + +LK +
Sbjct 2383 ILSALNMKAAMGALYSGKKKDHFSEISEEKFDNILQASCERLYSGRMGVWNGSLKAELRP 2442
Query 4943 KNRARTVAGVSICSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKT 4996
+ + S + + K+ + +G +KFYGGW +L +
Sbjct 2443 QEKVLANKTRSFTAAPIDTLLAGKVCVDDFNNKFYSLHLKIPSTVGITKFYGGWDRLLDS 2502
Query 4997 VYSDVENPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVL 5055
+ G + D ++ P +L VL + L N +++
Sbjct 2503 LPDGWVYCDADGSQF---DSSLTPYLLNA----VLEMRLRLMEEWDLGEQMLKNLYTEIV 2555
Query 5056 SEMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGN 5105
++ G++ K G +SG +T N++ I A L GN
Sbjct 2556 YTPILTPDGTIVKKFKGNNSGQPSTVVDNTLMVIMAVYYAAEK--LGIKGN 2604
>sp|Q65399|POLG_BCMNN Genome polyprotein OS=Bean common mosaic
necrosis virus (strain NL-3) OX=500578 PE=2 SV=1
Length=3066
Score = 45.1 bits (105), Expect = 0.038, Method: Composition-based stats.
Identities = 54/280 (19%), Positives = 107/280 (38%), Gaps = 46/280 (16%)
Query 4846 DYYRYNLPTMCD------IRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFN 4899
D+++YN P M + + + V+++ F + + I ++L+ A
Sbjct 2360 DFFKYNKPVMLNEVNFEAFEKAVEGVKIMMIEFGFNECVYVTDPDDIYDSLNMKAAVGAQ 2419
Query 4900 KWGKARLYYDSM-SYEDQDALFA------YTKRNVIPTITQMNLK---YAISAKNRARTV 4949
GK + Y+ M S++ + LF Y ++ + + L+ + K R T
Sbjct 2420 YKGKKQDYFQDMDSFDKERLLFLSCERLFYGQKGIWNGSLKAELRPLEKVQANKTRTFTA 2479
Query 4950 A------GVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVEN 5003
A G +C N QF+ L +G +KFYGGW +++ +
Sbjct 2480 APIDTLLGAKVCVDDFNNQFYSFNLI-------CPWTVGMTKFYGGWDKLMRAL------ 2526
Query 5004 PHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVL-SEMVMC- 5061
P GW Y D + + + L+L + + + E + L +E+V
Sbjct 2527 PD--GWVYCHADGSQFDS--SLTPLLLNSVLSIRSFFMED-WWVGKEMLENLYAEIVYTP 2581
Query 5062 ----GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVN 5097
G+++ K G +SG +T N++ + + +
Sbjct 2582 ILTPDGTIFKKFRGNNSGQPSTVVDNTLMVVISMYYSCIK 2621
>sp|Q83044|R1A_LIYV9 Replicase polyprotein 1a OS=Lettuce infectious
yellows virus (isolate United States/92) OX=651355 GN=ORF1a
PE=4 SV=1
Length=1873
Score = 45.1 bits (105), Expect = 0.040, Method: Composition-based stats.
Identities = 56/297 (19%), Positives = 103/297 (35%), Gaps = 51/297 (17%)
Query 5607 PPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVEC 5666
PPG GK+ L ++ A S+ V L + + L D I V+
Sbjct 1574 PPGAGKTTTIAKLMSKDLKNKVKCLALSYTKVGRL--ELIDKLKKDG---IEKPEKYVKT 1628
Query 5667 FDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDP 5726
+D F +N+ + VN DE+ M + ++ ++ GD
Sbjct 1629 YDSFLMNNDN---ILEIVNLYC---------DEVFMMHAGHFLTLLTKIAYQNGYCYGDV 1676
Query 5727 AQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLK 5786
Q+P + + P Y + + + D + RCP + +S L
Sbjct 1677 NQIP----FINRDPYTPAYLSREFFRKQDLNYDTY---TYRCPLDTCYLLSNL------- 1722
Query 5787 AHKDKSAQCFKMFYKGVITHD----VSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5842
KD+ ++ GV + ++N I VV E P A +++ +
Sbjct 1723 --KDEMGNI--IYAGGVKNVNEVYPTIRSLNLFGINVVGEV----PVEYNAKYLTFTQDE 1774
Query 5843 NAVASKILGLP------TQTVDSSQGSEYDYVIFTQTT--ETAHSCNVNRFNVAITR 5891
+ + TV+ +QG + V + + ++N+F VAI+R
Sbjct 1775 KLNLQRHIDSQGGCRNAVSTVNEAQGCTFSEVNLVRLVQFDNPVMSDINQFVVAISR 1831
>sp|P21231|POLG_SBMVN Genome polyprotein OS=Soybean mosaic virus
(strain N) OX=12223 PE=1 SV=2
Length=3066
Score = 44.7 bits (104), Expect = 0.043, Method: Composition-based stats.
Identities = 47/279 (17%), Positives = 100/279 (36%), Gaps = 28/279 (10%)
Query 4828 ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF-----DCYDGGCINA 4882
K FF + +++ D+ + + ++ ++ + + + + YD + A
Sbjct 2352 AFKRDFFKYNKPVVLNEVDFQSFER-AVAGVKLMMMEFDFKECVYVTDPDEIYDSLNMKA 2410
Query 4883 NQVIVNNLDKSAGF--PFNKWGKARLYY---DSMSYEDQDALFAYTKRNVIPTITQMNLK 4937
V K + + + K RL Y + + Y ++ K + P K
Sbjct 2411 A-VGAQYKGKKQDYFSGMDSFDKERLLYLSCERLFYGEKGVWNGSLKAELRPIEKVQANK 2469
Query 4938 YAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTV 4997
T+ G +C N QF+ L +G +KFY GW +++++
Sbjct 2470 TRTFTAAPIDTLLGAKVCVDDFNNQFYSLNLT-------CPWTVGMTKFYRGWDKLMRSL 2522
Query 4998 YSDVENPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLS 5056
H G + D ++ P +L VL + L N A+++
Sbjct 2523 PDGWVYCHADGSQF---DSSLTPLLLNA----VLDVRSFFMEDWWVGREMLENLYAEIVY 2575
Query 5057 EMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5094
++ G+++ K G +SG +T N++ + +
Sbjct 2576 TPILAPDGTIFKKFRGNNSGQPSTVVDNTLMVVIAMYYS 2614
>sp|Q84934|POLG_PPVSK Genome polyprotein OS=Plum pox potyvirus
(strain SK 68) OX=103927 PE=3 SV=1
Length=3140
Score = 44.7 bits (104), Expect = 0.050, Method: Composition-based stats.
Identities = 59/330 (18%), Positives = 114/330 (35%), Gaps = 46/330 (14%)
Query 4846 DYYRYNLP---TMCDIRQLLFVVEVV-----DKYFDCYDGGCINANQVIVNNLDKSAGFP 4897
D +Y+ P D Q ++VV K F+ + + I + L+ A
Sbjct 2364 DLMKYSKPIVVGAVDCEQFERALDVVISMLISKGFE--ECNYVTDPDDIFSALNMKAAVG 2421
Query 4898 FNKWGKARLYYDSMSYED-QDALFAYTKRNVI--PTITQMNLKYAISAKNRARTVAGVSI 4954
GK R Y+ + S +D +D + A KR + + +LK + K + S
Sbjct 2422 ALYSGKKRDYFKNASEQDKEDFIKASCKRLFMGKKGVWNGSLKAELRPKEKVEANKTRSF 2481
Query 4955 CSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKTVYSDVENPHLMG 5008
+ + K+ + +G +KF GGW +L+ + G
Sbjct 2482 TAAPIDTLLGGKVCVDDFNNQFYSLNLHCPWSVGMTKFRGGWDKLLRALPDGWIYCDADG 2541
Query 5009 WDYPKCDRAM-PNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMC-GGSLY 5066
+ D ++ P ++ + ++ LA L+N +++ + G++
Sbjct 2542 SQF---DSSLSPYLINAVLNIRLA----FMEEWDIGEQMLSNLYTEIVYTPIATPDGTIV 2594
Query 5067 VKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRN 5126
K G +SG +T N++ I + + D ++ C Y
Sbjct 2595 KKFKGNNSGQPSTVVDNTLMVILAMTYSLLKLGYHPDTHECI-------------CRYFV 2641
Query 5127 RDVDTDF-----VNEFYAYLRKHFSMMILS 5151
D Y L++HFS + L+
Sbjct 2642 NGDDLVLAVHPAYESMYDELQEHFSQLGLN 2671
>sp|Q83045|R1AB_LIYV9 Replicase polyprotein 1ab OS=Lettuce infectious
yellows virus (isolate United States/92) OX=651355 PE=3
SV=2
Length=2379
Score = 44.7 bits (104), Expect = 0.051, Method: Composition-based stats.
Identities = 56/297 (19%), Positives = 103/297 (35%), Gaps = 51/297 (17%)
Query 5607 PPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVEC 5666
PPG GK+ L ++ A S+ V L + + L D I V+
Sbjct 1574 PPGAGKTTTIAKLMSKDLKNKVKCLALSYTKVGRL--ELIDKLKKDG---IEKPEKYVKT 1628
Query 5667 FDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDP 5726
+D F +N+ + VN DE+ M + ++ ++ GD
Sbjct 1629 YDSFLMNNDN---ILEIVNLYC---------DEVFMMHAGHFLTLLTKIAYQNGYCYGDV 1676
Query 5727 AQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLK 5786
Q+P + + P Y + + + D + RCP + +S L
Sbjct 1677 NQIP----FINRDPYTPAYLSREFFRKQDLNYDTY---TYRCPLDTCYLLSNL------- 1722
Query 5787 AHKDKSAQCFKMFYKGVITHD----VSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5842
KD+ ++ GV + ++N I VV E P A +++ +
Sbjct 1723 --KDEMGNI--IYAGGVKNVNEVYPTIRSLNLFGINVVGEV----PVEYNAKYLTFTQDE 1774
Query 5843 NAVASKILGLP------TQTVDSSQGSEYDYVIFTQTT--ETAHSCNVNRFNVAITR 5891
+ + TV+ +QG + V + + ++N+F VAI+R
Sbjct 1775 KLNLQRHIDSQGGCRNAVSTVNEAQGCTFSEVNLVRLVQFDNPVMSDINQFVVAISR 1831
>sp|Q5HTX9|PGLB_CAMJR Undecaprenyl-diphosphooligosaccharide--protein
glycotransferase OS=Campylobacter jejuni (strain RM1221)
OX=195099 GN=pglB PE=1 SV=1
Length=713
Score = 43.9 bits (102), Expect = 0.062, Method: Composition-based stats.
Identities = 30/197 (15%), Positives = 66/197 (34%), Gaps = 21/197 (11%)
Query 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
+L ++LY+ F I+ MS F V ++P + + M
Sbjct 84 TLTYWLYKITPFSFESIILYMSTFLSSLV----------VIPIILLANEYKRPLMGFVAA 133
Query 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
+ + ++SG+ D ++ + +L M + D + + +Y
Sbjct 134 LLASVANSYYNRTMSGYYDTDMLVIVLPMFILFFMVRMILKKDFFSLIAL--PLFIGIYL 191
Query 3721 VYYGNALDQAISMWALIISVT--------SNYSGVVTTVMFLARGIVFMCVEYCPIFFIT 3772
+Y ++ +++ L + T Y V+ + + L+ F I F
Sbjct 192 WWYPSSYTLNVALIGLFLIYTLIFHRKEKIFYIAVILSSLTLSNIAWFYQSAIIVILFAL 251
Query 3773 GNTLQCIMLVYCFLGYF 3789
L+ L + +G
Sbjct 252 F-ALEQKRLNFMIIGIL 267
>sp|Q0P9C8|PGLB_CAMJE Undecaprenyl-diphosphooligosaccharide--protein
glycotransferase OS=Campylobacter jejuni subsp. jejuni
serotype O:2 (strain ATCC 700819 / NCTC 11168) OX=192222 GN=pglB
PE=1 SV=1
Length=713
Score = 43.9 bits (102), Expect = 0.063, Method: Composition-based stats.
Identities = 30/197 (15%), Positives = 66/197 (34%), Gaps = 21/197 (11%)
Query 3601 SLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWV 3660
+L ++LY+ F I+ MS F V ++P + + M
Sbjct 84 TLTYWLYKITPFSFESIILYMSTFLSSLV----------VIPIILLANEYKRPLMGFVAA 133
Query 3661 MRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYK 3720
+ + ++SG+ D ++ + +L M + D + + +Y
Sbjct 134 LLASVANSYYNRTMSGYYDTDMLVIVLPMFILFFMVRMILKKDFFSLIAL--PLFIGIYL 191
Query 3721 VYYGNALDQAISMWALIISVT--------SNYSGVVTTVMFLARGIVFMCVEYCPIFFIT 3772
+Y ++ +++ L + T Y V+ + + L+ F I F
Sbjct 192 WWYPSSYTLNVALIGLFLIYTLIFHRKEKIFYIAVILSSLTLSNIAWFYQSAIIVILFAL 251
Query 3773 GNTLQCIMLVYCFLGYF 3789
L+ L + +G
Sbjct 252 F-ALEQKRLNFMIIGIL 267
>sp|Q58914|Y1519_METJA Uncharacterized protein MJ1519 OS=Methanocaldococcus
jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1
/ JCM 10045 / NBRC 100440) OX=243232 GN=MJ1519 PE=4 SV=1
Length=1175
Score = 43.9 bits (102), Expect = 0.085, Method: Composition-based stats.
Identities = 24/141 (17%), Positives = 44/141 (31%), Gaps = 12/141 (9%)
Query 5598 MQKYSTLQGPPGTGKSHFAIGLALYYPS----ARIVYTACSHAAVDALCEKALKYLPIDK 5653
+ L GP GTGK+ + +I + + + EK
Sbjct 578 KNRVGILTGPAGTGKTTVIKTIMELMKEVLGLNKIYILTPTGKSAMVVNEKLNNLATAKT 637
Query 5654 CSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNA 5713
R I F + + + D ++ DE SM + +
Sbjct 638 IHRYIAEE-----FKDYFEGDNYFILRLDKITGNDKKEIDALIIDESSMVDIETMGRLLG 692
Query 5714 RLRA---KHYVYIGDPAQLPA 5731
++ K+ +++GD QLP
Sbjct 693 TIKLDNLKYLIFVGDINQLPP 713
>sp|Q9RT63|RECD2_DEIRA ATP-dependent RecD2 DNA helicase OS=Deinococcus
radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871
/ CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM
B-1422 / R1) OX=243230 GN=recD2 PE=1 SV=1
Length=715
Score = 43.5 bits (101), Expect = 0.087, Method: Composition-based stats.
Identities = 32/142 (23%), Positives = 47/142 (33%), Gaps = 25/142 (18%)
Query 5594 QKVGMQKYSTLQGPPGTGKSHFAIGLALYYP--SARIVYTACSHAAVDALCE-KALKYLP 5650
Q G + L G PGTGKS +A + A + A L E
Sbjct 349 QLAG-HRLVVLTGGPGTGKSTTTKAVADLAESLGLEVGLCAPTGKAARRLGEVTGRTAST 407
Query 5651 IDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATN-YDLS 5709
+ + P R N L D+++ DE+SM + LS
Sbjct 408 VHRLLGYGPQGFR--------------------HNHLEPAPYDLLIVDEVSMMGDALMLS 447
Query 5710 VVNARLRAKHYVYIGDPAQLPA 5731
++ A + +GD QLP
Sbjct 448 LLAAVPPGARVLLVGDTDQLPP 469
>sp|Q9Z1Q1|NEST_MESAU Nestin (Fragments) OS=Mesocricetus auratus
OX=10036 GN=NES PE=1 SV=2
Length=1818
Score = 43.5 bits (101), Expect = 0.10, Method: Composition-based stats.
Identities = 33/192 (17%), Positives = 72/192 (38%), Gaps = 17/192 (9%)
Query 844 ELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMA 903
E D ++K E E F ++ ++L E L++
Sbjct 520 ETDRPLEKENGEPLKPVEEEDQL----FETLIEKEGQESLSSPEEEDQETDRPLEKEEDQ 575
Query 904 TY-YLFDESGEFKLASHMYCSFYPPDEDEEEGD--CEEEEFEPSTQYEYGTEDDYQGKPL 960
L ++ G+ L+S P+E+++E D E+E EP E +
Sbjct 576 LVERLVEKEGQESLSS--------PEEEDQETDRPLEKENGEPLKPVEEEDQLFETLIEK 627
Query 961 EFGATSAALQPEEEQEEDWLDDDSQQTVGQ--QDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
E + ++ + E+++ + L+ + Q V + + +++ ++ + E LE E
Sbjct 628 EGQESLSSPEEEDQETDRPLEKEEDQLVERLVEKEGQESLSSPEEEDQETDRPLEKEEDQ 687
Query 1019 VVQTIEVNSFSG 1030
+V+T+
Sbjct 688 LVETLIEKQGQE 699
Score = 39.7 bits (91), Expect = 1.5, Method: Composition-based stats.
Identities = 23/122 (19%), Positives = 54/122 (44%), Gaps = 12/122 (10%)
Query 907 LFDESGEFKLASHMYCSFYPPDEDEEEGD--CEEEEFEPSTQYEYGTEDDYQGKPLEFGA 964
L ++ G+ L+S P+E+++E D E+E EP E + E
Sbjct 502 LIEKEGQESLSS--------PEEEDQETDRPLEKENGEPLKPVEEEDQLFETLIEKEGQE 553
Query 965 TSAALQPEEEQEEDWLDDDSQQTVGQ--QDGSEDNQTTTIQTIVEVQPQLEMELTPVVQT 1022
+ ++ + E+++ + L+ + Q V + + +++ ++ + E LE E ++
Sbjct 554 SLSSPEEEDQETDRPLEKEEDQLVERLVEKEGQESLSSPEEEDQETDRPLEKENGEPLKP 613
Query 1023 IE 1024
+E
Sbjct 614 VE 615
Score = 38.9 bits (89), Expect = 2.9, Method: Composition-based stats.
Identities = 39/225 (17%), Positives = 75/225 (33%), Gaps = 38/225 (17%)
Query 844 ELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMA 903
E D ++K E E F ++ ++L E L++
Sbjct 598 ETDRPLEKENGEPLKPVEEEDQL----FETLIEKEGQESLSSPEEEDQETDRPLEKEEDQ 653
Query 904 TY-YLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYG-----------T 951
L ++ G+ L+S P +ED+E E+E + +
Sbjct 654 LVERLVEKEGQESLSS-------PEEEDQETDRPLEKEEDQLVETLIEKQGQECLSSPEE 706
Query 952 EDDYQGKPLE-------------FGATSAALQPEEEQEEDWL--DDDSQQTVGQQDGSED 996
ED +PLE G S + EE+QE L ++ + ++ +
Sbjct 707 EDQETDRPLEKEEDQRVERLIEKEGQESLSSPEEEDQETYRLLEKENGEPLKPVEEEDQR 766
Query 997 NQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIK 1041
+ + E L+ E +V+T+E ++ L +N+
Sbjct 767 VERLIEKEDQESLSSLKEEDQRIVKTLERENWESLRSLDENLDTV 811
>sp|Q73L97|RLME_TREDE Ribosomal RNA large subunit methyltransferase
E OS=Treponema denticola (strain ATCC 35405 / DSM 14222
/ CIP 103919 / JCM 8153 / KCTC 15104) OX=243275 GN=rlmE PE=3
SV=1
Length=199
Score = 41.6 bits (96), Expect = 0.12, Method: Composition-based stats.
Identities = 35/126 (28%), Positives = 49/126 (39%), Gaps = 4/126 (3%)
Query 6888 PTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGF 6947
P + + D LN F D G +V +D +I D T N T + G
Sbjct 76 PLDSSVYDERLNFFQGDMFDK--GIIKSVKELGPYDAVICDAAPATTGNKTVDTARSSGL 133
Query 6948 FTYICGFIQQKLALGGSVAIKITE-HSWNADLYKLMGHFAWWTAFVTNVNASSS-EAFLI 7005
+ Q++L GGS +KI + L L F AF SSS E +LI
Sbjct 134 VELALYYAQEQLKQGGSFVVKIFQGGDQQIHLNNLRKCFKTARAFKPEACRSSSFETYLI 193
Query 7006 GCNYLG 7011
G ++ G
Sbjct 194 GLDFKG 199
>sp|P32270|DDA_BPT4 ATP-dependent DNA helicase dda OS=Enterobacteria
phage T4 OX=10665 GN=dda PE=1 SV=2
Length=439
Score = 42.8 bits (99), Expect = 0.12, Method: Composition-based stats.
Identities = 36/159 (23%), Positives = 60/159 (38%), Gaps = 24/159 (15%)
Query 5598 MQKYSTLQGPPGTGKSH---FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5654
+ + T+ GP GTGK+ F I + I+ A +HAA +K L L +
Sbjct 24 KKHHVTINGPAGTGKTTLTKFIIEALISTGGTGIILAAPTHAA-----KKILSKLSGKEA 78
Query 5655 SRIIPARARVECFDKFKVNS-TLEQYVFCTVNALPETTAD-IVVFDEISMATNYDLSVVN 5712
S I K+N T E+ V +P+ +++ DE+SM ++
Sbjct 79 STI---------HSILKINPVTYEENVLFEQKEVPDLAKCRVLICDEVSMYDRKLFKILL 129
Query 5713 ARLRA-KHYVYIGDPAQL----PAPRTLLTKGTLEPEYF 5746
+ + + IGD Q+ P T + F
Sbjct 130 STIPPWCTIIGIGDNKQIRPVEPGENTAYISPFFTHKDF 168
>sp|Q5A1V3|POA1_CANAL ADP-ribose 1''-phosphate phosphatase OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=POA1
PE=3 SV=2
Length=156
Score = 40.8 bits (94), Expect = 0.12, Method: Composition-based stats.
Identities = 31/160 (19%), Positives = 54/160 (34%), Gaps = 26/160 (16%)
Query 1038 VYIKNADIVEEAKKVKPTVVV-NAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGP 1096
+ D+ A V++ +A N + GGG+A A+ + E Y N
Sbjct 2 IQYIKGDLFTHAIPAGKKVILAHACNTHGSWGGGIA-AVFRKKFPKSNNEYSQYCHKNSN 60
Query 1097 LKVGGSCVLSGHNL---------------AKHCLHVVGPNVNKGEDIQLLKSAYENFNQH 1141
L +G S ++ + +H D+ S Y+ +
Sbjct 61 L-LGTSFIIESDQPNILIACLFTSDFNQTPEQIVHFT---KQSIADLARKVSDYKEVEKC 116
Query 1142 E---VLLAPLLSAGIFGADPI--HSLRVCVDTVRTNVYLA 1176
+ + P ++AGIFG S D + NVY+
Sbjct 117 DGKVAINMPKINAGIFGVPWEDTESALQEFDNLHFNVYVI 156
>sp|Q73IS9|RLME_WOLPM Ribosomal RNA large subunit methyltransferase
E OS=Wolbachia pipientis wMel OX=163164 GN=rlmE PE=3 SV=1
Length=192
Score = 41.2 bits (95), Expect = 0.13, Method: Composition-based stats.
Identities = 31/152 (20%), Positives = 56/152 (37%), Gaps = 15/152 (10%)
Query 6873 DKGVAPG--TAVLRQWLPTGTLLVDSDLN--------DFVSDADSTLIGDCATVHTANKW 6922
D G +PG + V Q G +V D+ +F+ K+
Sbjct 40 DLGASPGGWSQVASQ---KGANVVALDIKPMNAINGVEFIQCDIINEFEILREKFKDQKF 96
Query 6923 DLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADL-YKL 6981
D+I+SDM + ++ F + L+ GG+ +KI + + D +L
Sbjct 97 DVILSDMAPESCGLKSLDHIRIMLLCEAALNFAKHFLSHGGTFVVKIFQGESDKDFCNEL 156
Query 6982 MGHFAWWTAFVTNVNAS-SSEAFLIGCNYLGK 7012
F F + S S+E +L+ ++G
Sbjct 157 KKMFKTVKYFKPKSSRSESTEMYLVSLGFIGS 188
>sp|P45612|UVRD_MYCCT Probable DNA helicase II homolog OS=Mycoplasma
capricolum subsp. capricolum (strain California kid /
ATCC 27343 / NCTC 10154) OX=340047 GN=uvrD PE=3 SV=2
Length=722
Score = 42.8 bits (99), Expect = 0.13, Method: Composition-based stats.
Identities = 24/130 (18%), Positives = 50/130 (38%), Gaps = 15/130 (12%)
Query 5662 ARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVN-ARLRAKHY 5720
++ + FK N+ + + NA D V+ DE S++ + H
Sbjct 197 LQIYVYRLFKQNN---EILNKWRNA-----YDYVLVDEFQDTNELQFSLIKFLTINTNHL 248
Query 5721 VYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALV 5780
+GDP Q T+ + + + + + + L R +I+D ++ +
Sbjct 249 TVVGDPDQ-----TIYSWRGAKLDIILNFNKTYSNAI-SIVLNQNYRSTKQILDISNSFI 302
Query 5781 YDNKLKAHKD 5790
+NK + HK+
Sbjct 303 KNNKFREHKE 312
>sp|A0QS28|RECD_MYCS2 RecBCD enzyme subunit RecD OS=Mycolicibacterium
smegmatis (strain ATCC 700084 / mc(2)155) OX=246196
GN=recD PE=3 SV=1
Length=554
Score = 42.4 bits (98), Expect = 0.17, Method: Composition-based stats.
Identities = 28/112 (25%), Positives = 45/112 (40%), Gaps = 7/112 (6%)
Query 5624 PSARIVYTACSHAAVDALCEKA---LKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYV 5680
PS RI A + A L E + L + + R+ A T ++
Sbjct 182 PSPRIALAAPTGKAAARLQEAVQLEIDQLDLIERRRLTGLHATTLHRLLGPRPDTSSRFR 241
Query 5681 FCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK-HYVYIGDPAQLPA 5731
N LP D++V DE SM + ++ + +R + V +GDP QL +
Sbjct 242 HHRANRLPH---DVIVVDETSMVSLTMMARLLEAVRPQTRLVLVGDPDQLAS 290
>sp|Q9YKD6|RDRP_TOMS1 Replicase large subunit OS=Tomato mosaic
virus (strain S-1) OX=138314 PE=3 SV=1
Length=1616
Score = 42.8 bits (99), Expect = 0.19, Method: Composition-based stats.
Identities = 70/407 (17%), Positives = 123/407 (30%), Gaps = 75/407 (18%)
Query 5595 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5654
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFEED---LILVPGRQAAEMIRRRA------NAS 872
Query 5655 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM----ATNYDLSV 5710
I+ + V D F +N + DE M N+ + +
Sbjct 873 GIIVATKDNVRTVDSFLMN----------YGKGARCQFKRLFIDEGLMLHTGCVNFLVEM 922
Query 5711 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5770
+ + + GD Q+P + G P +F + + T RCPA
Sbjct 923 SLSDIAYVY----GDTQQIPYINRV--TGFPYPAHFAKL-----EVDEVETRRTTLRCPA 971
Query 5771 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5830
++ ++ Y+ + + + G + + S + + LT +
Sbjct 972 DVTHFLNQR-YEGHVMCTSSEKKSVSQEMVSGAASINPVSK------PLKGKILTFTQSD 1024
Query 5831 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAIT 5890
++A+ Y TV QG Y V + T T S I
Sbjct 1025 KEALLSRGYT------------DVHTVHEVQGETYADVSLVRLTPTPVSI--------IA 1064
Query 5891 RAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPT 5950
R +L +S L++ ++ + E V+ D KV G
Sbjct 1065 RDSPHVLVSLSRHT--KSLKYYTVVMDPLVSIIRDLERVSSYLLDMYKVDAG-----TQX 1117
Query 5951 HLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
L VD+ FK L V P IS M F + + G +
Sbjct 1118 QLQVDSVFKNFNLFVATPKTGD-------ISDMQFYYDKCLPGNSTL 1157
>sp|Q9ILI5|NS1AB_TASV2 Non-structural polyprotein 1AB OS=Turkey
astrovirus 2 OX=246343 GN=ORF1 PE=3 SV=2
Length=1638
Score = 42.4 bits (98), Expect = 0.22, Method: Composition-based stats.
Identities = 45/260 (17%), Positives = 91/260 (35%), Gaps = 22/260 (8%)
Query 4845 YDYYRYNLPTMCDIRQLLFVV---EVVDKYFDCYDGGCINANQVIVNNLDKSAGFP-FNK 4900
++ + Y+ P + FV+ +V + D I N++ + +P F
Sbjct 1213 FEKFHYHDPVDFVEQYAEFVLLCDNMVLREHDYMANSNITPIMSTEKNVNSTPAYPKFQA 1272
Query 4901 WGKARLYYDSMSYEDQDALF---AYTKRNVI--PTITQMNLKYAISAKNRARTVAGVSIC 4955
+ Y + +++ + R + + LK + R +
Sbjct 1273 YDSEAEYLEDCGWQEYLDVVSDPETINRRPLWWCFLKNEVLKREKIEDSDIRMILCTDPI 1332
Query 4956 STMTNRQFHQKLLKSIAA-TRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKC 5014
T F Q + T + +G + F+GG ++ +Y D + + D+ +
Sbjct 1333 FTRIGAMFEQDQNNRMKQQTEIRSAQVGWTPFFGGLDRRVRRLYGDGDRYFV-EMDWTRY 1391
Query 5015 DRAMPNML----RIMASLVLARKHTTCCSLSHRFYRLANECAQVLSE--MVMCGGSLYVK 5068
D +P L R + L H T + RL N + L E +++ G +
Sbjct 1392 DGTIPKSLFWRIRQIRFFFLHDSHKT-----PKMRRLYNWYVKNLLEKIILLPTGEVCQV 1446
Query 5069 PGGTSSGDATTAYANSVFNI 5088
G SG +T N++ N+
Sbjct 1447 KKGNPSGQFSTTVDNNMINV 1466
>sp|A8GUJ3|ATP6_RICB8 ATP synthase subunit a OS=Rickettsia bellii
(strain OSU 85-389) OX=391896 GN=atpB PE=3 SV=1
Length=242
Score = 41.2 bits (95), Expect = 0.22, Method: Composition-based stats.
Identities = 26/156 (17%), Positives = 49/156 (31%), Gaps = 19/156 (12%)
Query 3583 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAM-SAFAMMFVKHKHAFLCLF-- 3639
++ T+ +L F + + + FA+ I+ + FVKH FL LF
Sbjct 87 VIFTLFVFILFCNLFGMIPYGFTVTSHIIITFALAILVFLMVTIVGFVKHGMHFLSLFLP 146
Query 3640 ------LLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLI 3693
L P + + F + PAS +R+ ++ A ++
Sbjct 147 HGTPLWLAPLMIIIELFTYLARPASLSLRLAA----------NMMAGHILLKVIASFVIT 196
Query 3694 LMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQ 3729
LM + + + + Y L
Sbjct 197 LMIYLKFLPIPLMVILIGFEIFVAILQAYIFTILSC 232
>sp|P17595|ALPHA_BSMV Replication protein alpha-A OS=Barley stripe
mosaic virus OX=12327 PE=1 SV=1
Length=1139
Score = 42.4 bits (98), Expect = 0.23, Method: Composition-based stats.
Identities = 58/298 (19%), Positives = 106/298 (36%), Gaps = 40/298 (13%)
Query 5586 FSSNVANYQKVGMQ--KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCE 5643
++ V Y V + ++ + G PG GKS + R V A D L E
Sbjct 816 YNKLVDVYALVADRPLRFELIDGVPGCGKSTMILN---SCDIRREVVVGEGRNATDDLRE 872
Query 5644 KALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMA 5703
+ + ++ + A RV TL+ + +P+ AD FDE
Sbjct 873 RFKRKKNLNSKT----ANHRVR---------TLDSLLLAEGPCVPQ--ADRFHFDEALKV 917
Query 5704 TNYDLSVVNARLRAKHYVYIGDPAQLP--APRTLLTKGTLEPEYFNSVCRLMKTIGPDMF 5761
+ +L A + GD AQLP + P+Y ++ I P +
Sbjct 918 HYGAIMFCADKLGASEILAQGDRAQLPMICRVEGIELQFQSPDYTKTI------INPKL- 970
Query 5762 LGTCRRCPAEIVDTVSAL-VYDNKLKAHKDKSAQCFK--MFYKGVITHDVSSAINRPQIG 5818
R P ++ +SA Y K K ++ K ++ +G T + ++ +
Sbjct 971 --RSYRIPGDVAFYLSAKEFYKVKGIPQKVITSNSVKRSLYARGETTPERFVSLLDVPVR 1028
Query 5819 VVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTET 5876
+LT A ++++ + + + T+ +QG Y+ VI + T
Sbjct 1029 KDTHYLTFLQAEKESLM------SHLIPKGVKKESISTIHEAQGGTYENVILVRLQRT 1080
>sp|Q1RGZ3|ATP6_RICBR ATP synthase subunit a OS=Rickettsia bellii
(strain RML369-C) OX=336407 GN=atpB PE=3 SV=1
Length=242
Score = 41.2 bits (95), Expect = 0.23, Method: Composition-based stats.
Identities = 26/156 (17%), Positives = 49/156 (31%), Gaps = 19/156 (12%)
Query 3583 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAM-SAFAMMFVKHKHAFLCLF-- 3639
++ T+ +L F + + + FA+ I+ + FVKH FL LF
Sbjct 87 VIFTLFVFILFCNLFGMIPYGFTVTSHIIITFALAILVFLMVTIVGFVKHGMHFLSLFLP 146
Query 3640 ------LLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLI 3693
L P + + F + PAS +R+ ++ A ++
Sbjct 147 HGTPLWLAPLMIIIELFTYLARPASLSLRLAA----------NMMAGHILLKVIASFVVT 196
Query 3694 LMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQ 3729
LM + + + + Y L
Sbjct 197 LMIYLKFLPIPLMVILIGFEIFVAILQAYIFTILSC 232
>sp|Q89249|RDRP_SBWMN Replicase large subunit OS=Soil-borne wheat
mosaic virus (strain United States/Nebraska/1981) OX=652673
GN=rep PE=3 SV=1
Length=1828
Score = 42.0 bits (97), Expect = 0.34, Method: Composition-based stats.
Identities = 54/286 (19%), Positives = 91/286 (32%), Gaps = 56/286 (20%)
Query 5600 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC----S 5655
+ + G PG GKS + + P +V A + L EK +K +
Sbjct 1021 RITLRDGVPGCGKSTWILN--NANPMKDMVLCV-GKEATEDLKEKFMKKHKCAESDLKRI 1077
Query 5656 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5715
R + + + +DKF+ A V FDE MA + L
Sbjct 1078 RTVDSFLMHD-YDKFR--------------------AATVHFDEALMAHAGIVYFCADIL 1116
Query 5716 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5775
AK + GD Q+P + ++ +Y I ++ R P ++
Sbjct 1117 GAKKVICQGDSQQIP---FINRVESITLQYAKL------AIDETEYVRLTYRSPVDVAHY 1167
Query 5776 VSAL-VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5834
++ Y K+ + K+ S P R A
Sbjct 1168 LTKKSWYSGGRVTTKNSVLRSMKVVGPRDAKPMTSVHC--------------VPYHRDAQ 1213
Query 5835 FISPYNSQNAVASKIL----GLPTQTVDSSQGSEYDYVIFTQTTET 5876
+++ S+ A K L + TV +QG +D VI + T
Sbjct 1214 YLTFTQSEKADLYKALRAKGPVEVNTVHETQGKTFDDVIVVRLKTT 1259
>sp|Q03QN6|TIG_LEVBA Trigger factor OS=Levilactobacillus brevis
(strain ATCC 367 / BCRC 12310 / CIP 105137 / JCM 1170 / LMG
11437 / NCIMB 947 / NCTC 947) OX=387344 GN=tig PE=3 SV=1
Length=436
Score = 41.2 bits (95), Expect = 0.36, Method: Composition-based stats.
Identities = 26/211 (12%), Positives = 63/211 (30%), Gaps = 15/211 (7%)
Query 819 APTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADA 878
A KVT + ++ ++DE +D + + +V + D
Sbjct 233 ATFKVTIHEVKEKQLPELDD-EFAKDVDEDVDSLEELEAKTKDRLKEQKVTAAHDAIEDE 291
Query 879 VIKTLQPVSELLTPLGIDLDEWSMATY--YLFDESGEFKLASHMYCSFYPPDEDEEEGDC 936
I +E+ L + YL + + + MY ED+
Sbjct 292 AISEAVDNAEIAAVPEAMLKDDIDRQMDQYLANMQ-QQGIEPKMYFQLTGTTEDDLRKQF 350
Query 937 EEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDD-DSQQTVGQQDGSE 995
+ + LE + ++P E++ + D SQ + +
Sbjct 351 AD----------GAEKRIKTNLVLEAVVEAEKIEPSEDEVAAEVKDLASQYGMEESAVRS 400
Query 996 DNQTTTIQTIVEVQPQLEMELTPVVQTIEVN 1026
++ + ++ +++ Q + +
Sbjct 401 ALSDDMLKHDIAIKSAVDLIADSAKQDKKKD 431
>sp|B9KDD4|PGLB_CAMLR Undecaprenyl-diphosphooligosaccharide--protein
glycotransferase OS=Campylobacter lari (strain RM2100
/ D67 / ATCC BAA-1060) OX=306263 GN=pglB PE=1 SV=1
Length=712
Score = 41.2 bits (95), Expect = 0.39, Method: Composition-based stats.
Identities = 30/194 (15%), Positives = 67/194 (35%), Gaps = 16/194 (8%)
Query 3592 LVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFN 3651
L S+ +L ++LY F I+ MSAF F L ++P + +
Sbjct 77 LSYFGSSLSTLTYWLYSILPFSFESIILYMSAF----------FASLIVVPIILIAREYK 126
Query 3652 MVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTL 3711
+ + + ++SG+ D ++ +++L+ T+ D L
Sbjct 127 LTTYGFIAALLGSIANSYYNRTMSGYYDTDMLVLVLPMLILLTFIRLTINKDIFT--LLL 184
Query 3712 MNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFI 3771
V ++Y +Y ++ +M I + Y+ V + + + + +
Sbjct 185 SPVFIMIYLWWYPSSYSLNFAM----IGLFGLYTLVFHRKEKIFYLTIALMIIALSMLAW 240
Query 3772 TGNTLQCIMLVYCF 3785
++L F
Sbjct 241 QYKLALIVLLFAIF 254
>sp|Q03F26|TIG_PEDPA Trigger factor OS=Pediococcus pentosaceus
(strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w) OX=278197
GN=tig PE=3 SV=1
Length=435
Score = 41.2 bits (95), Expect = 0.41, Method: Composition-based stats.
Identities = 42/322 (13%), Positives = 96/322 (30%), Gaps = 34/322 (11%)
Query 704 NLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDL 763
G + S + + +E + K ++ + E P E + G +
Sbjct 121 YKGVKVIKQSTRV------TSKEVDEEIEKKREQQAELVLKEGKPAENGDTVTIDFDGSV 174
Query 764 QPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTF-------TLK 816
+ +A LV + + + + + N TF L+
Sbjct 175 DGVAFDGGKADNYDLV-----LGSNSFIPGFEDQLIGHNTDEDVDVNVTFPDDYQAEDLQ 229
Query 817 GG-APTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVV 875
G A KV + E+ ++DE +D + + K ++ +
Sbjct 230 GKDALFKVKIHEIKTKELPELDD-EFAKDVDEDVDSLEDLKVKTKEEIKSRKIQAASDAK 288
Query 876 ADAVIKTLQPVSELLTPLGIDLDEWSMATY--YLFDESGEFKLASHMYCSFYPPDEDEEE 933
++ +E+ L+E YL + + ++ MY ED+
Sbjct 289 ETEAVQAAVDNAEIAEIPEAMLNEDVDRQVNQYLANMQ-QQGISPEMYFQLTGSSEDQLR 347
Query 934 GDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQ-TVGQQD 992
E LE + + P +++ + D ++Q + ++
Sbjct 348 DQLR----------EGAENRVKTTLVLEAIVEAEKIDPSDDEVAAEIKDLAEQYGMEEKA 397
Query 993 GSEDNQTTTIQTIVEVQPQLEM 1014
I+ V ++ +E+
Sbjct 398 VRSALSEDMIKHDVAIKSAVEL 419
>sp|P20234|POLG_OMV Genome polyprotein (Fragment) OS=Ornithogalum
mosaic virus OX=12204 PE=3 SV=1
Length=1136
Score = 41.6 bits (96), Expect = 0.43, Method: Composition-based stats.
Identities = 53/291 (18%), Positives = 99/291 (34%), Gaps = 59/291 (20%)
Query 4839 NAAISDYDYYRYNLPTMCD----IRQLLFVVEVVDKYFDCYDGGC--INANQVIVNNLDK 4892
A + D +Y+ P + I+ V+ + D C + + + NL+
Sbjct 432 EAFVKDIM--KYSKPIVLGEVDFIKFEEGYNNVLRMFHDIGFEKCEYVTDSMEVYKNLNL 489
Query 4893 SAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQM-NLKYAI---SAKNRART 4948
A GK + Y++ MS ++ L VI + ++ + K+ + S K R
Sbjct 490 KAAVGAMYTGKKQQYFEGMSEDEIHQL-------VIASCFRLWSGKFGVWNGSLKAELRP 542
Query 4949 VAGVSICSTMTNR-------------------QFHQKLLKSIAATRGATVVIGTSKFYGG 4989
+ V C T T QF+ K L A +G K+Y G
Sbjct 543 LEKVQACKTRTFTAAPLDTLLGAKVCVDDFNAQFYDKHLT-------APWTVGICKYYKG 595
Query 4990 WHNMLKTVYSDVENPHLMGWDYPKCDRAM--PNMLRIMASLVLARKHTTCCSLSHRFYRL 5047
W + + GW Y D + ++ + + VL + L
Sbjct 596 WDTFMNKLPE--------GWLYCDADGSQFDSSLTPFLINSVLRLRLEFMEDWDIGARML 647
Query 5048 ANECAQVLSEMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVN 5097
+N +++ + G++ K G +SG +T N+ + + N
Sbjct 648 SNLYTEIIYTPIATPDGTVVKKFRGNNSGQPSTVVDNT---LMVVLAMNYA 695
>sp|B0ULY1|ATP6_METS4 ATP synthase subunit a OS=Methylobacterium
sp. (strain 4-46) OX=426117 GN=atpB PE=3 SV=1
Length=251
Score = 40.1 bits (92), Expect = 0.51, Method: Composition-based stats.
Identities = 27/177 (15%), Positives = 59/177 (33%), Gaps = 20/177 (11%)
Query 3583 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMM-FVKHKHAFLCLFLL 3641
L+ ++ +LVL F + + + F + ++ + + F+ H FL LF+
Sbjct 90 LVFSLFMFVLVLNLFGMIPYAFTVTSHIIVTFMLALVVILTVVIYGFMAHGVHFLDLFVP 149
Query 3642 PSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVY 3701
P + WL + ++ + S + ++
Sbjct 150 PG-------------------VPGWLKPLIVAIEVVSFISRPISLSVRLFANMLAGHIAL 190
Query 3702 DDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGI 3758
A V L+ AL AI+ ++++V Y T ++L+ +
Sbjct 191 KIFAGFVPALLAAGIWGILSPLPLALSVAITALEMLVAVLQAYVFATLTSIYLSDAL 247
>sp|Q4FRM3|RS20_PSYA2 Small ribosomal subunit protein bS20 OS=Psychrobacter
arcticus (strain DSM 17307 / VKM B-2377 / 273-4)
OX=259536 GN=rpsT PE=3 SV=1
Length=88
Score = 37.4 bits (85), Expect = 0.51, Method: Composition-based stats.
Identities = 18/82 (22%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
Query 3956 AFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQ--RK----LEKMADQAM 4009
A A++ ++ + +++ K ++ A + D DAA + +K L++MAD+ +
Sbjct 7 ARKRARQNTKRRQNSASQRSMVRTYLKRVDAAIAAKDYDAATEAYKKAVPVLDRMADKGI 66
Query 4010 TQMYKQARSEDKRAKVTSAMQT 4031
K AR + + K +Q
Sbjct 67 LHKNKAARRKSRLNKTIKGLQA 88
>sp|P89676|RDRP_TOMK2 Replicase large subunit OS=Tomato mosaic
virus (strain Kazakh K2) OX=138312 PE=3 SV=1
Length=1616
Score = 41.2 bits (95), Expect = 0.53, Method: Composition-based stats.
Identities = 69/403 (17%), Positives = 119/403 (30%), Gaps = 67/403 (17%)
Query 5595 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5654
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFEED---LILVPGRQAAEMIRRRA------NAS 872
Query 5655 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNAR 5714
I+ + V D F +N + DE M ++ +
Sbjct 873 GIIVATKDNVRTVDSFLMN----------YGKGARCQFKRLFIDEGLMLHTGCVNFLVEM 922
Query 5715 LRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVD 5774
GD Q+P + G P +F + + T RCPA++
Sbjct 923 SLCDIAYVYGDTQQIPYINRV--TGFPYPAHFAKL-----EVDEVETRRTTLRCPADVTH 975
Query 5775 TVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5834
++ Y+ + + + G + + S + + LT + ++A+
Sbjct 976 FLNQR-YEGHVMCTSSEKKSVSQEMVSGAASINPVSK------PLKGKILTFTQSDKEAL 1028
Query 5835 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKV 5894
Y TV QG Y V + T T S I R
Sbjct 1029 LSRGY------------ADVHTVHEVQGETYADVSLVRLTPTPVSI--------IARDSP 1068
Query 5895 GILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSV 5954
+L +S L++ ++ + E V+ D KV G L V
Sbjct 1069 HVLVSLSRHT--KSLKYYTVVMDPLVSIIRDLERVSSYLLDMYKVDAG-----TQXQLQV 1121
Query 5955 DTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
D+ FK L V P IS M F + + G +
Sbjct 1122 DSVFKNFNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTL 1157
>sp|Q9Q1T8|RDRP_TOMK1 Replicase large subunit OS=Tomato mosaic
virus (strain Kazakh K1) OX=138311 PE=3 SV=2
Length=1616
Score = 41.2 bits (95), Expect = 0.55, Method: Composition-based stats.
Identities = 69/403 (17%), Positives = 119/403 (30%), Gaps = 67/403 (17%)
Query 5595 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5654
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFEED---LILVPGRQAAEMIRRRA------NAS 872
Query 5655 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNAR 5714
I+ + V D F +N + DE M ++ +
Sbjct 873 GIIVATKDNVRTVDSFLMN----------YGKGARCQFKRLFIDEGLMLHTGCVNFLVEM 922
Query 5715 LRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVD 5774
GD Q+P + G P +F + + T RCPA++
Sbjct 923 SLCDIAYVYGDTQQIPYINRV--TGFPYPAHFAKL-----EVDEVETRRTTLRCPADVTH 975
Query 5775 TVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5834
++ Y+ + + + G + + S + + LT + ++A+
Sbjct 976 FLNQR-YEGHVMCTSSEKKSVSQEMVSGAASINPVSK------PLKGKILTFTQSDKEAL 1028
Query 5835 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKV 5894
Y TV QG Y V + T T S I R
Sbjct 1029 LSRGY------------ADVHTVHEVQGETYADVSLVRLTPTPVSI--------IARDSP 1068
Query 5895 GILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSV 5954
+L +S L++ ++ + E V+ D KV G L V
Sbjct 1069 HVLVSLSRHT--KSLKYYTVVMDPLVSIIRDLERVSSYLLDMYKVDAG-----TQXQLQV 1121
Query 5955 DTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
D+ FK L V P IS M F + + G +
Sbjct 1122 DSVFKNFNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTL 1157
>sp|P03587|RDRP_TOML Replicase large subunit OS=Tomato mosaic
virus (strain L) OX=12252 PE=1 SV=2
Length=1616
Score = 41.2 bits (95), Expect = 0.56, Method: Composition-based stats.
Identities = 69/403 (17%), Positives = 119/403 (30%), Gaps = 67/403 (17%)
Query 5595 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5654
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFEED---LILVPGRQAAEMIRRRA------NAS 872
Query 5655 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNAR 5714
I+ + V D F +N + DE M ++ +
Sbjct 873 GIIVATKDNVRTVDSFLMN----------YGKGARCQFKRLFIDEGLMLHTGCVNFLVEM 922
Query 5715 LRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVD 5774
GD Q+P + G P +F + + T RCPA++
Sbjct 923 SLCDIAYVYGDTQQIPYINRV--TGFPYPAHFAKL-----EVDEVETRRTTLRCPADVTH 975
Query 5775 TVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5834
++ Y+ + + + G + + S + + LT + ++A+
Sbjct 976 FLNQR-YEGHVMCTSSEKKSVSQEMVSGAASINPVSK------PLKGKILTFTQSDKEAL 1028
Query 5835 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKV 5894
Y TV QG Y V + T T S I R
Sbjct 1029 LSRGY------------ADVHTVHEVQGETYADVSLVRLTPTPVSI--------IARDSP 1068
Query 5895 GILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSV 5954
+L +S L++ ++ + E V+ D KV G L V
Sbjct 1069 HVLVSLSRHT--KSLKYYTVVMDPLVSIIRDLERVSSYLLDMYKVDAG-----TQXQLQV 1121
Query 5955 DTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
D+ FK L V P IS M F + + G +
Sbjct 1122 DSVFKNFNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTL 1157
>sp|Q11KH9|ATP6_CHESB ATP synthase subunit a OS=Chelativorans
sp. (strain BNC1) OX=266779 GN=atpB PE=3 SV=1
Length=249
Score = 39.7 bits (91), Expect = 0.61, Method: Composition-based stats.
Identities = 22/109 (20%), Positives = 43/109 (39%), Gaps = 13/109 (12%)
Query 3570 SAVKRTIKGTHHWLLLTILTSLLVLVQST----QWSLFFFLYENAFLPFAMGIIAMSAFA 3625
+++ R G+H + SL + V + FF + + + FA+ ++ +
Sbjct 70 ASMLRDAAGSHGMRFFPFVFSLFMFVLVANLLGLFPYFFTVTSHIVVTFALALLVIGTVL 129
Query 3626 MMFV-KHKHAFLCLF--------LLPSLATVAYFNMVYMPASWVMRIMT 3665
+ KH FL LF LLP + + + + P S +R+
Sbjct 130 VYGFWKHGFGFLKLFVPEGVPGVLLPLVVLIEVISFLSRPISLSVRLFA 178
>sp|Q6XW15|POLG_BTMV Genome polyprotein OS=Beet mosaic virus OX=114921
PE=3 SV=1
Length=3085
Score = 40.8 bits (94), Expect = 0.70, Method: Composition-based stats.
Identities = 46/268 (17%), Positives = 98/268 (37%), Gaps = 28/268 (10%)
Query 4846 DYYRYNLPTMCDIRQLLFVVEVVDKYFDCYD----GGC--INANQVIVNNLDKSAGFPFN 4899
D+ +Y P + + V + + G C + I ++L+ A
Sbjct 2365 DFLKYAGPITVGVVNTNSFEDAVASVINMLEDLDYGECAYVTDPDSIFDSLNMKAAVGAL 2424
Query 4900 KWGKARLYYDSMSYEDQDALFAYTKRNVIPT---ITQMNLKYAISAKNRARTVAGVSICS 4956
GK + Y++ ++ +++ L + + + +LK + K + + +
Sbjct 2425 YKGKKKEYFEQLNTTEREDLLRLSCERLYEGKMGVWNGSLKAELRPKEKLEQNKTRTFTA 2484
Query 4957 TMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWD 5010
+ K+ R +G +KFYGGW+ +L+ + P GW
Sbjct 2485 APIDTLLGGKVCVDDFNNRFYSLNLKGPWSVGMTKFYGGWNELLQKL------PD--GWI 2536
Query 5011 YPKCDRA-MPNMLR--IMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMC-GGSLY 5066
Y D + + L ++ ++V R+H L N +++ ++ G++
Sbjct 2537 YCDADGSQFDSSLTPYLINAVVQIREH-FMEDWEIGRTMLRNFYTEIVYTPILTPDGTIV 2595
Query 5067 VKPGGTSSGDATTAYANSVFNICQAVTA 5094
K G +SG +T N++ I A
Sbjct 2596 KKFKGNNSGQPSTVVDNTLMVILAMHYA 2623
>sp|O11436|POLG_RGMVD Genome polyprotein OS=Ryegrass mosaic virus
(isolate Denmark/Danish) OX=652106 PE=3 SV=1
Length=3086
Score = 40.8 bits (94), Expect = 0.76, Method: Composition-based stats.
Identities = 31/138 (22%), Positives = 54/138 (39%), Gaps = 18/138 (13%)
Query 4960 NRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCD--RA 5017
N QF+ LK +G +KF+G W++ L + GWDY D R
Sbjct 2448 NNQFYAAHLK-------GPWTVGITKFFGRWNDFLSELPP--------GWDYFDADGSRF 2492
Query 5018 MPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMC-GGSLYVKPGGTSSGD 5076
++ + + VL + + + L N +++ + GS+ K G +SG
Sbjct 2493 DSSLTPFLLNAVLNIRKKFMINWAFGQRCLGNLYTEIIYTPIATPDGSVVKKMRGNNSGQ 2552
Query 5077 ATTAYANSVFNICQAVTA 5094
+T N++ I A
Sbjct 2553 PSTVVDNTIMVIIAMQYA 2570
>sp|P29152|POLG_PSBMV Genome polyprotein OS=Pea seed-borne mosaic
virus (strain DPD1) OX=31736 PE=1 SV=1
Length=3206
Score = 40.4 bits (93), Expect = 0.88, Method: Composition-based stats.
Identities = 47/207 (23%), Positives = 76/207 (37%), Gaps = 26/207 (13%)
Query 4948 TVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLM 5007
T+ G +C N F+ L+ +G +KFY GW+ L + P
Sbjct 2591 TLLGGKVCVDDFNNFFYSCHLR-------GPWTVGITKFYAGWNEFLSKL------PD-- 2635
Query 5008 GWDYPKCD--RAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMC-GGS 5064
GW Y D R ++ + + VL + L N +++ + GS
Sbjct 2636 GWLYCDADGSRFDSSLTPYLINAVLELRLRFMEEWDAGEQMLKNLYTEIIYTPIATPDGS 2695
Query 5065 LYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLY 5124
+ K G +SG +T N++ I + LL D D+ VR + + L
Sbjct 2696 VIKKTKGNNSGQPSTVVDNTLMVILAMQYS--LQLLGVDFET-QDEVVRYFANG--DDLL 2750
Query 5125 RNRDVDTDFVNEFYAYLRKHFSMMILS 5151
D +FV L HFS + L+
Sbjct 2751 IAVRPDCEFV---LKGLEIHFSNLGLN 2774
>sp|Q64962|RDRP_ASPVP RNA replication polyprotein OS=Apple stem
pitting virus (isolate PA66) OX=651356 GN=ORF1 PE=3 SV=1
Length=2183
Score = 40.4 bits (93), Expect = 0.93, Method: Composition-based stats.
Identities = 46/310 (15%), Positives = 103/310 (33%), Gaps = 47/310 (15%)
Query 5594 QKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDK 5653
+ V +K + G G GKS P I + + + +++ D
Sbjct 1362 ELVHERKLIMILGTFGCGKSSLFKKFIEKSPGKAITFVSPRRSLAESI--------NHDL 1413
Query 5654 CSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNA 5713
+ + + D V + ++++ E VV DEI + + ++
Sbjct 1414 GLARVGGKKTGKSKDLKNVRVKTFELFILHLDSIKE--GHTVVIDEIQLFPPGYIDLIIL 1471
Query 5714 RLRAK-HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEI 5772
L+ + + GDP Q ++ G + ++I
Sbjct 1472 GLKPNVNIIIAGDPCQ---------------SDYDCSSDRHIFAGSE----------SDI 1506
Query 5773 VDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGV-----VREFLTRN 5827
+ +S Y + + + ++ +FY + + + + + ++EF
Sbjct 1507 MRILSGRSYKFNILSQRFRN----PVFYGRLPCNLNKTRLTLDEEEYTLWDSIQEFSMMG 1562
Query 5828 PAWRKAVFISPYNSQNAVASKI-LGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN 5886
V +S + + VA+ + L + T S G + T E+A + + R+
Sbjct 1563 RKDCPVVLVSSFEEKKIVAAHLGLKMKCITYGESTGLNFQKGAILVTYESALTSD-RRWW 1621
Query 5887 VAITRAKVGI 5896
A++R I
Sbjct 1622 TALSRFSHDI 1631
>sp|Q84687|RDRP_PCV87 Replicase large subunit OS=Peanut clump
virus (isolate 87/TGTA2) OX=652837 GN=rep PE=3 SV=2
Length=1672
Score = 40.4 bits (93), Expect = 0.93, Method: Composition-based stats.
Identities = 43/219 (20%), Positives = 71/219 (32%), Gaps = 58/219 (26%)
Query 5570 YVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIV 5629
+ ++ +YP+L Q K + G PG GKS + + R +
Sbjct 834 FNKLVLVYPSL----------PKTQL----KVRLIDGVPGCGKSTWILSNC---DLDRQI 876
Query 5630 YTACSHAAVDAL----CEKALKYLPIDKCSRIIPA---RARVECFDKFKVNSTLEQYVFC 5682
A A D L EK ++ R + + + F+ F
Sbjct 877 VLAEGREATDDLRRRFTEKGFPKKRCEERVRTVHSFMLKPLSRRFNSFH----------- 925
Query 5683 TVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLE 5742
FDE MA + + L A+ + GD Q+P + + +L+
Sbjct 926 --------------FDEALMAHAGMIYICGRMLNAREVICQGDSKQIPFIN-RVEQISLK 970
Query 5743 PEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVY 5781
FN V R + RCP +IV ++ Y
Sbjct 971 YSSFNVVEREH--------VRKTYRCPLDIVYYLNKKKY 1001
>sp|P41299|NU5M_BALMU NADH-ubiquinone oxidoreductase chain 5 OS=Balaenoptera
musculus OX=9771 GN=MT-ND5 PE=3 SV=1
Length=606
Score = 40.1 bits (92), Expect = 0.97, Method: Composition-based stats.
Identities = 19/188 (10%), Positives = 59/188 (31%), Gaps = 15/188 (8%)
Query 3595 VQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVY 3654
++ +L+ N + + + K + L +P + +
Sbjct 44 FITSLIPAMMYLHTNQETLISNWHWITIQTLKLTLSFKMDYFSLMFMPVALFITWS---- 99
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNV 3714
+M W D ++ F + + +LIL+TA ++ + +
Sbjct 100 -----IMEFSMWYMHSDPYINQFFK---YLLLFLITMLILVTANNLFQLFIGWE-GVGIM 150
Query 3715 LTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVF--MCVEYCPIFFIT 3772
L+ ++G ++ A++ + + + + FL+ + + +
Sbjct 151 SFLLIGWWFGRTDANTAALQAILYNRIGDIGLLASMAWFLSNMNTWDLQQIFMLNQNPLN 210
Query 3773 GNTLQCIM 3780
+ ++
Sbjct 211 FPLMGLVL 218
>sp|P39369|YJHR_ECOLI Putative uncharacterized protein YjhR OS=Escherichia
coli (strain K12) OX=83333 GN=yjhR PE=5 SV=1
Length=338
Score = 39.7 bits (91), Expect = 1.0, Method: Composition-based stats.
Identities = 29/140 (21%), Positives = 52/140 (37%), Gaps = 30/140 (21%)
Query 5796 FKMFYKGVITHDVSSAINRPQIGVVREFLTRN----------PAWRKAVFISPYNSQ-NA 5844
+ + + S N + + +L + P ++ ++P+++Q NA
Sbjct 3 YLHIDGRGMKPNGGSRHNPLEAETIAAWLVAHKDDIERHYGEPLYKVVGVVTPFSAQVNA 62
Query 5845 VASKILGLPTQ-----------TVDSSQGSEYDYVIFTQTTETAHS------CNVNRFNV 5887
+ + L TV S QG+E V+F+ + H N NV
Sbjct 63 IKMSLRKLEINGKDEQGLLTVGTVHSLQGAERAIVLFSPV-YSKHEDGRFLDSNSTILNV 121
Query 5888 AITRAKVGILCIMSDRDLYD 5907
A++RAK L D DL +
Sbjct 122 AVSRAKDSFLVFG-DMDLIE 140
>sp|Q8K9A8|RECD_BUCAP RecBCD enzyme subunit RecD OS=Buchnera aphidicola
subsp. Schizaphis graminum (strain Sg) OX=198804 GN=recD
PE=3 SV=1
Length=602
Score = 40.1 bits (92), Expect = 1.1, Method: Composition-based stats.
Identities = 14/40 (35%), Positives = 21/40 (53%), Gaps = 1/40 (3%)
Query 5693 DIVVFDEISMATNYDLSVVNARLRAK-HYVYIGDPAQLPA 5731
DI++ DE SM +S + + L K ++IGD QL
Sbjct 267 DILIIDEASMIDILMMSNILSALSKKTKIIFIGDHNQLKP 306
>sp|Q2KBW1|ATP6_RHIEC ATP synthase subunit a OS=Rhizobium etli
(strain CFN 42 / ATCC 51251) OX=347834 GN=atpB PE=3 SV=1
Length=250
Score = 38.9 bits (89), Expect = 1.1, Method: Composition-based stats.
Identities = 20/92 (22%), Positives = 38/92 (41%), Gaps = 9/92 (10%)
Query 3583 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMM-FVKHKHAFLCLF-- 3639
L+ ++ +L + FF + + FA+ I+ +S + F KH FL +F
Sbjct 87 LVFSLFMFVLTANLLGMFPYFFTITSQIIVTFALAILVISTVLIYGFYKHGFHFLNVFVP 146
Query 3640 ------LLPSLATVAYFNMVYMPASWVMRIMT 3665
LLP + + + + P S +R+
Sbjct 147 SGVPGILLPLVVAIEIISFLSRPISLSVRLFA 178
>sp|Q08534|R1AB_BYVU Replicase polyprotein 1ab OS=Beet yellows
virus (isolate Ukraine) OX=478555 GN=1a-1b PE=1 SV=2
Length=3094
Score = 39.7 bits (91), Expect = 1.5, Method: Composition-based stats.
Identities = 49/299 (16%), Positives = 95/299 (32%), Gaps = 44/299 (15%)
Query 5607 PPGTGKSHFAIGL--ALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARV 5664
PPG GK+ I + + ++ TA + ++ + + K + +D+ + R R+
Sbjct 2250 PPGGGKTTTLIKVFCETFSKVNSLILTA-NKSSREEILAKV-NRIVLDEGDTPLQTRDRI 2307
Query 5665 ECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIG 5724
D + +N+ T ++ DE M + + G
Sbjct 2308 LTIDSYLMNNRG-------------LTCKVLYLDECFMVHAGAAVACIEFTKCDSAILFG 2354
Query 5725 DPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPD--MFLGTCRRCPAEIVDTVSALVYD 5782
D Q + G + L + + + ++ RCP ++
Sbjct 2355 DSRQ-------IRYGRCSELDTAVLSDLNRFVDDESRVYGEVSYRCPWDVCA-------- 2399
Query 5783 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREF--LTRNPAWRKAVFISPYN 5840
L K+ + G + V + + EF LT + +K + S
Sbjct 2400 -WLSTFYPKTVATTNLVSAGQSSMQVREIESVDDVEYSSEFVYLTMLQSEKKDLLKSFGK 2458
Query 5841 SQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTT---ETAHSCNVNRFNVAITRAKVGI 5896
+ K L TV +QG Y V +T + N VA++R +
Sbjct 2459 RSRSSVEKPTVL---TVHEAQGETYRKVNLVRTKFQEDDPFRSE-NHITVALSRHVESL 2513
>sp|P15576|NU1M_LEITA NADH-ubiquinone oxidoreductase chain 1 OS=Leishmania
tarentolae OX=5689 GN=ND1 PE=3 SV=1
Length=313
Score = 38.9 bits (89), Expect = 1.7, Method: Composition-based stats.
Identities = 34/253 (13%), Positives = 83/253 (33%), Gaps = 36/253 (14%)
Query 3607 YENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVA----YFNMVY---MPASW 3659
+ P GI F + + +L ++ + + YF + + + +
Sbjct 45 FFGILTPITDGIKLFIKFIIFVISFDIIYLIGAMIITACCIFLGWFYFPIGFILLLDTGF 104
Query 3660 VMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVL-TLV 3718
+ +M + + + S F + C +++S V L M ++ L + +L
Sbjct 105 TLTVMLCVHVFCSMFSTFFV-GCFLFSSCFVYLSAMRTMFFSIISESGIFLLYTTIYSLD 163
Query 3719 YKVYYGNALDQ----AISMWALIISVTSNYSGVVTTVMFL----------ARGIVFMCVE 3764
Y ++G I+ + + + + V + L + + + E
Sbjct 164 YFSFFGIKDVCVGQIYITNFYIAGVLFISVFWVSMLLDGLKLPFDYMECESELVAGLITE 223
Query 3765 YCPIFFITGNTLQC-------IMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVST 3817
FF+ + L+ ++ G C+ + L+ +F + Y ++T
Sbjct 224 LSGFFFVLYSVLEINHILLTTLLFASLCFGGLFICFKAILILIFGFFYPRVIGYRLKITT 283
Query 3818 QE------FRYMN 3824
+ YM
Sbjct 284 AQAFILIFLFYMC 296
>sp|P22706|TRAI2_ECOLX Multifunctional conjugation protein TraI
OS=Escherichia coli OX=562 GN=traI PE=3 SV=1
Length=1756
Score = 39.7 bits (91), Expect = 1.7, Method: Composition-based stats.
Identities = 28/140 (20%), Positives = 45/140 (32%), Gaps = 28/140 (20%)
Query 5600 KYSTLQGPPGTGKSH------FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDK 5653
+++ +QG G GK+ A+ + R+V +H AV + + +
Sbjct 986 RFTVVQGYAGVGKTTQFRAVMSAVNMLPASERPRVVGLGPTHRAVGEMRSAGVDAQTLAS 1045
Query 5654 CSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNA 5713
+ R F N L + DE SM N D++ A
Sbjct 1046 FLHDTQLQQRSGETPDFS-------------NTL-------FLLDESSMVGNTDMARAYA 1085
Query 5714 RL--RAKHYVYIGDPAQLPA 5731
+ V GD QL A
Sbjct 1086 LIAAGGGRAVASGDTDQLQA 1105
>sp|P19723|POLG_PRSVP Genome polyprotein (Fragment) OS=Papaya
ringspot virus (strain P / mutant HA 5-1) OX=31730 PE=3 SV=1
Length=675
Score = 39.3 bits (90), Expect = 1.8, Method: Composition-based stats.
Identities = 50/287 (17%), Positives = 100/287 (35%), Gaps = 36/287 (13%)
Query 4940 ISAKNRARTVA------GVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNM 4993
++ K R+ T A G +C N F+ K ++ +G +KFY GW
Sbjct 32 LAKKTRSFTAAPLDTLLGAKVCVDDFNNWFYSKNME-------CPWTVGMTKFYKGWDEF 84
Query 4994 LKTVYSDVENPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHTTCCSLSHRFYRLANECA 5052
L+ G + D ++ P +L + S+ L L N
Sbjct 85 LRKFPDGWVYCDADGSQF---DSSLTPYLLNAVLSIRLWAMED----WDIGEQMLKNLYG 137
Query 5053 QVLSEMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNK----- 5106
++ ++ G++ K G +SG +T N++ + A A T +
Sbjct 138 EITYTPILTPDGTIVKKFKGNNSGQPSTVVDNTLMVLITMYYALRKAGYDTKTQEDMCVF 197
Query 5107 -IADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHF---SMMILSDDAVV---CFN 5159
I + H +E + + + Y + ++H ++ +S ++ +
Sbjct 198 YINGDDLCIAIHPDHEHVLDSFSSSFAELGLKYDFAQRHRNKQNLWFMSHRGILIDDIYI 257
Query 5160 STYASQGLVASIKNFKSVL--YYQNNVFMSEAKCWTETDLTKGPHEF 5204
+ +VA ++ KS L + + + + W DLT F
Sbjct 258 PKLEPERIVAILEWDKSKLPEHRLEAITAAMIESWGHGDLTHQIRRF 304
>sp|Q58889|PRS2_METJA Putative 26S proteasome regulatory subunit
homolog MJ1494 OS=Methanocaldococcus jannaschii (strain ATCC
43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) OX=243232
GN=MJ1494 PE=3 SV=2
Length=371
Score = 38.9 bits (89), Expect = 1.9, Method: Composition-based stats.
Identities = 33/124 (27%), Positives = 46/124 (37%), Gaps = 11/124 (9%)
Query 5517 VQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAP-----TLVPQEHYV 5571
V+ G+Y F+ D ++ +TY G TS TV L P T + +
Sbjct 69 VKEGDYLFDNSILPD-YAFKVISTYPKEGGMI---TSETVFKLQTPKKVLRTQFKKAKFS 124
Query 5572 RITGLYPTLNISDEFSSNVANYQKVGM--QKYSTLQGPPGTGKSHFAIGLALYYPSARIV 5629
I G + N + G K GPPGTGK+ A LA S+ I+
Sbjct 125 EIIGQEEAKKKCRIIMKYLENPKLFGEWAPKNVLFYGPPGTGKTLMARALATETNSSFIL 184
Query 5630 YTAC 5633
A
Sbjct 185 VKAP 188
>sp|Q83943|1A_OLV2I Replication protein 1a OS=Olive latent virus
2 (isolate Italy) OX=650489 GN=ORF1a PE=3 SV=1
Length=908
Score = 39.3 bits (90), Expect = 1.9, Method: Composition-based stats.
Identities = 71/329 (22%), Positives = 117/329 (36%), Gaps = 56/329 (17%)
Query 5600 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5659
K + + G G GK++ IV+TA D L A K D S++ P
Sbjct 625 KKTWIDGVAGCGKTY------------EIVHTADIFKK-DDLILTANKKSQEDIFSQLKP 671
Query 5660 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5719
+C + + T++ Y+ P+ A + DE + L
Sbjct 672 G---TDCAKRIR---TVDSYLLK-----PDVQAKRLFIDEAGLVHPGKLLAAMRFAECDD 720
Query 5720 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5779
+ GD Q+P + +L+P F L + T RCPA++ T++ L
Sbjct 721 CLLFGDSEQIPFVNIV---ESLQPAKF-----LKLEVDAREVRETTYRCPADVTATLATL 772
Query 5780 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWR-KAVFISP 5838
+K K K V + ++SA + LT A + + V ++
Sbjct 773 --------YKKKKIVTKSKVLKSVTSKSLASASAVSGLDPHSWHLTMYQADKAELVRVAR 824
Query 5839 YNSQNAVASKILGLPTQTVDSSQG------SEYDYVIFTQ-TTETAHSCNVNRFNVAITR 5891
N + V K +TV +QG Y + F Q + AH+ VAI+R
Sbjct 825 TNQMDDVWIKE---HIKTVHEAQGISVPHVKLYRFKTFDQPLFDAAHAEAYR--LVAISR 879
Query 5892 AKVGILCIMSDRDLYDK---LQFTSLEIP 5917
I ++ L L+F +IP
Sbjct 880 HTQSFTYIGVNQHLCKADRMLKFVICQIP 908
>sp|Q14151|SAFB2_HUMAN Scaffold attachment factor B2 OS=Homo sapiens
OX=9606 GN=SAFB2 PE=1 SV=1
Length=953
Score = 39.3 bits (90), Expect = 1.9, Method: Composition-based stats.
Identities = 52/365 (14%), Positives = 103/365 (28%), Gaps = 25/365 (7%)
Query 686 LALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGE 745
+ ++ G + G SK ++CVK LK +E G
Sbjct 57 MERLKKAVKEEGQDPDEI--GIELEATSKKSAKRCVKG---------LKMEEEGTEDNGL 105
Query 746 TLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPN 805
+ E++ +LQ + ++ V + E + +
Sbjct 106 EDDSRDGQEDMEASLENLQNMGMMDMSVLDETEVANS---SAPDFGEDGTDGLLDSFCDS 162
Query 806 MMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELG 865
P + + S+N F++ I+ E E
Sbjct 163 KEYVAAQLRQLPAQPPEHAVDGEGFKNTLETSSLN--FKVTPDIE----ESLLEPENEKI 216
Query 866 TEVNEFACV---VADAVIKTLQPVSELLTPLGIDLDEWSMATYY--LFDESGEFKLASHM 920
++ C V + + QP ++ + +G D + E G+ LAS
Sbjct 217 LDILGETCKSEPVKEESSELEQPFAQDTSSVGPDRKLAEEEDLFDSAHPEEGDLDLASES 276
Query 921 YCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWL 980
D + E E E + +P +++A+ E EE
Sbjct 277 TAHAQSSKADSLLAVVKREPAEQPGDGERTDCEPVGLEPAVEQSSAASELAEASSEELAE 336
Query 981 DDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYI 1040
+ +D ED + EV P + T +++SF + +
Sbjct 337 APTEAPSPEARDSKEDGRKFDFDACNEVPPAPKESSTSEGADQKMSSFKEEKDIKPIIKD 396
Query 1041 KNADI 1045
+ +
Sbjct 397 EKGRV 401
>sp|P24978|NU5M_BALPH NADH-ubiquinone oxidoreductase chain 5 OS=Balaenoptera
physalus OX=9770 GN=MT-ND5 PE=3 SV=1
Length=606
Score = 38.9 bits (89), Expect = 2.0, Method: Composition-based stats.
Identities = 19/188 (10%), Positives = 59/188 (31%), Gaps = 15/188 (8%)
Query 3595 VQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVY 3654
++ +L+ N + + + K + L +P + +
Sbjct 44 FITSLVPAMVYLHTNQETLISNWHWITIQTLKLTLSFKMDYFSLMFMPVALFITWS---- 99
Query 3655 MPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNV 3714
+M W D ++ F + + +LIL+TA ++ + +
Sbjct 100 -----IMEFSMWYMHSDPYINQFFK---YLLLFLITMLILVTANNLFQLFIGWE-GVGIM 150
Query 3715 LTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMC--VEYCPIFFIT 3772
L+ ++G ++ A++ + + + + FL+ + + +
Sbjct 151 SFLLIGWWFGRTDANTAALQAILYNRIGDIGLLASMAWFLSNMNTWDLEQIFMLNQNPLN 210
Query 3773 GNTLQCIM 3780
+ ++
Sbjct 211 FPLMGLVL 218
>sp|Q5NQH8|RLME_ZYMMO Ribosomal RNA large subunit methyltransferase
E OS=Zymomonas mobilis subsp. mobilis (strain ATCC 31821
/ ZM4 / CP4) OX=264203 GN=rlmE PE=3 SV=1
Length=221
Score = 38.1 bits (87), Expect = 2.1, Method: Composition-based stats.
Identities = 37/153 (24%), Positives = 57/153 (37%), Gaps = 14/153 (9%)
Query 6873 DKGVAPG--TAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANK--------- 6921
D G+APG + V R+ P + V DL + T+ + T A K
Sbjct 66 DLGIAPGGWSQVARKKAPQAKI-VGIDLLEAAPIEGVTIFQNDFTDPEAQKKLIEALGGA 124
Query 6922 WDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKL 6981
DL++SDM + ++ F + L GGS K+ + DL L
Sbjct 125 ADLVLSDMAANTIGHAQTDHLRTMALVEEAAVFASETLREGGSFVAKVLAGGADKDLVAL 184
Query 6982 MGH-FAWW-TAFVTNVNASSSEAFLIGCNYLGK 7012
+ F A SSE ++I N+ G+
Sbjct 185 LKRLFGQVKHAKPPASRRESSEWYVIAQNFRGE 217
>sp|Q3KNA1|MRGB2_MOUSE Mas-related G-protein coupled receptor
member B2 OS=Mus musculus OX=10090 GN=Mrgprb2 PE=2 SV=2
Length=338
Score = 38.5 bits (88), Expect = 2.3, Method: Composition-based stats.
Identities = 27/203 (13%), Positives = 66/203 (33%), Gaps = 12/203 (6%)
Query 3611 FLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMV 3670
FL M A + + + +LC + + ++ + ++ ++ +
Sbjct 61 FLGIRMHTNAFTVYILNLAMADFLYLCSQF---VICLLIAFYIFYSIDINIPLVLYVVPI 117
Query 3671 DTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRV-----WTLMNVLTLVYKVYYGN 3725
LSG + + + ++ + R + W + +L L+ G
Sbjct 118 FAYLSGLSILSTISIERCLSVIWPIWYRCKRPRHTSAITCFVLWVMSLLLGLLEGKACGL 177
Query 3726 ALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPI----FFITGNTLQCIML 3781
+ S W V +N VV + + + +C T+ +L
Sbjct 178 LFNSFDSYWCETFDVITNIWSVVFFGVLCGSSLTLLVRIFCGSQRIPMTRLYVTITLTVL 237
Query 3782 VYCFLGYFCTCYFGLFCLLNRYF 3804
V+ G Y+ L+ ++ ++
Sbjct 238 VFLIFGLPFGIYWILYQWISNFY 260
>sp|P18247|POLG_PVYN Genome polyprotein OS=Potato virus Y (strain
N) OX=12219 PE=1 SV=2
Length=3063
Score = 39.3 bits (90), Expect = 2.3, Method: Composition-based stats.
Identities = 25/119 (21%), Positives = 48/119 (40%), Gaps = 9/119 (8%)
Query 4981 IGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHTTCCS 5039
+G +KFYGGW +L+ + + G + D ++ P ++ VL + T
Sbjct 2499 VGMTKFYGGWDKLLRRLPENWVYCDADGSQF---DSSLTPYLINA----VLTIRSTYMED 2551
Query 5040 LSHRFYRLANECAQVLSEMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVN 5097
L N +++ + G++ K G +SG +T NS+ + A +
Sbjct 2552 WDVGLQMLRNLYTEIVYTPISTPDGTIVKKFRGNNSGQPSTVVDNSLMVVLAMHYALIK 2610
>sp|Q91ZC6|MRGA6_MOUSE Mas-related G-protein coupled receptor
member A6 OS=Mus musculus OX=10090 GN=Mrgpra6 PE=2 SV=2
Length=301
Score = 38.1 bits (87), Expect = 2.6, Method: Composition-based stats.
Identities = 25/173 (14%), Positives = 57/173 (33%), Gaps = 17/173 (10%)
Query 3644 LATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDD 3703
+ T + N +++ + R++ ++G + + + ++ + R +
Sbjct 69 ILTFSSPNSIFINCLYTFRVL-------LYIAGLNMLSAISIERCLSVMCPIWYRCHRPE 121
Query 3704 GARR-----VWTLMNVLTLVYKVYYG-----NALDQAISMWALIISVTSNYSGVVTTVMF 3753
+W L +L ++Y+ + G D + + + VV V
Sbjct 122 HTSTVMCAMIWVLSLLLCILYRYFCGFLDTKYEDDYGCLAMNFLTTAYLMFLFVVLCVSS 181
Query 3754 LARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRL 3806
LA C T+ +LV+ G C Y+ L + F +
Sbjct 182 LALLARLFCGAGRMKLTRLYVTITLTLLVFLLCGLPCGFYWFLLSKIKNVFSV 234
>sp|Q2FQC0|KUP_METHJ Probable potassium transport system protein
Kup OS=Methanospirillum hungatei JF-1 (strain ATCC 27890
/ DSM 864 / NBRC 100397 / JF-1) OX=323259 GN=kup PE=3 SV=1
Length=611
Score = 38.5 bits (88), Expect = 2.6, Method: Composition-based stats.
Identities = 22/135 (16%), Positives = 45/135 (33%), Gaps = 8/135 (6%)
Query 3021 VDAVNLLTNMFTPLIQPIGALDISASIV--------AGGIVAIVVTCLAYYFMRFRRAFG 3072
+++ T + P+ +D ++ + ++ I V C+ F R
Sbjct 313 SGIFSIIYQAITTHLLPMLPVDYTSDELRTQIYINTVNWLLCIAVICVLLIFQYSERLAS 372
Query 3073 EYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMF 3132
Y V + + L G+ ++ L Y + VS + H ++ +
Sbjct 373 AYGLAVTGTMSITGSFMIAIFLQRRKYLYMGIALIVTLVDITYFLSTVSKITHGGYLSLV 432
Query 3133 TPLVPFWITIAYIIC 3147
+PF I I Y
Sbjct 433 IAAIPFTIVIIYTSG 447
>sp|A1SSX2|RNFD_PSYIN Ion-translocating oxidoreductase complex
subunit D OS=Psychromonas ingrahamii (strain DSM 17664 / CCUG
51855 / 37) OX=357804 GN=rnfD PE=3 SV=1
Length=350
Score = 38.1 bits (87), Expect = 2.6, Method: Composition-based stats.
Identities = 28/190 (15%), Positives = 60/190 (32%), Gaps = 21/190 (11%)
Query 3502 YEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVR 3561
+ T D + + G+++ ++++ L NG I S + +
Sbjct 163 FTGSTLDGYSVAQLSVSIDGLSMATPLNTVRDALHNGFTVTEIFNSVQFK-----ASSWQ 217
Query 3562 QCS---GVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSL--------FFFLYENA 3610
Q G + K HW + + + ++ F L+ A
Sbjct 218 QIYWINGAFLAGGLILLFKRIVHWHIPMSFLLGIGIFSFIAFAYSPDLNAPPLFHLFSGA 277
Query 3611 FLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMV 3670
+ A I++ A VK + + LL + V N+ P + ++ L +
Sbjct 278 TMLGAFFILSDPVSASTTVKGRILYA---LLIAFIVVIIRNVGGYPDAVAFAVL--LGNM 332
Query 3671 DTSLSGFKLK 3680
L + +
Sbjct 333 CVPLIDYYTQ 342
>sp|P19724|POLG_PRSVW Genome polyprotein (Fragment) OS=Papaya
ringspot virus (strain W) OX=12207 PE=3 SV=1
Length=675
Score = 38.5 bits (88), Expect = 2.8, Method: Composition-based stats.
Identities = 50/287 (17%), Positives = 100/287 (35%), Gaps = 36/287 (13%)
Query 4940 ISAKNRARTVA------GVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNM 4993
++ K R+ T A G +C N F+ K ++ +G +KFY GW
Sbjct 32 LAKKTRSFTAAPLDTLLGAKVCVDDFNNWFYSKNME-------CPWTVGMTKFYKGWDEF 84
Query 4994 LKTVYSDVENPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHTTCCSLSHRFYRLANECA 5052
L+ G + D ++ P +L + S+ L L N
Sbjct 85 LRKFPDGWVYCDADGSQF---DSSLTPYLLNAVLSIRLWAMED----WDIGEQMLKNLYG 137
Query 5053 QVLSEMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNK----- 5106
++ ++ G++ K G +SG +T N++ + A A T +
Sbjct 138 EITYTPILTPDGTIVKKFKGNNSGQPSTVVDNTLMVLITMYYALRKAGYDTKTQEDMCVF 197
Query 5107 -IADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHF---SMMILSDDAVV---CFN 5159
I + H +E + + + Y + ++H ++ +S ++ +
Sbjct 198 YINGDDLCIAIHPDHEHVLDSFSRSFAELGLKYDFTQRHRNKQNLWFMSHRGILIDDIYI 257
Query 5160 STYASQGLVASIKNFKSVL--YYQNNVFMSEAKCWTETDLTKGPHEF 5204
+ +VA ++ KS L + + + + W DLT F
Sbjct 258 PKLEPERIVAILEWDKSKLPEHRLEAITAAMIESWGYGDLTHQIRRF 304
>sp|F1QGD2|ZDH24_DANRE Probable palmitoyltransferase ZDHHC24 OS=Danio
rerio OX=7955 GN=zdhhc24 PE=2 SV=1
Length=295
Score = 38.1 bits (87), Expect = 2.8, Method: Composition-based stats.
Identities = 25/183 (14%), Positives = 57/183 (31%), Gaps = 9/183 (5%)
Query 2220 SPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIA 2279
S ++ L +F+L ++ + ++ + LG + G+R Y +
Sbjct 55 STIWTGLHLFAQYFMLGNITWNASLFVKTNPSIRGVFLGGDTLGQGWRYCY--NCETHTP 112
Query 2280 TYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFY 2339
C+ C+VC+ D + + F + A +L+
Sbjct 113 PRCSHCYDCNVCVLRRDHHCVFFGQCVGFH-------NYRYFLTCLLFMWAGLLYAVVMN 165
Query 2340 VLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVH 2399
I++ ++ +V + W+M + + A A + + H
Sbjct 166 AEVFIFILKEGVTFHSVMLLLVPWIMLVSGQVTTRAFAFAFIADTCVVGFLLVAAFLFFH 225
Query 2400 VVD 2402
V
Sbjct 226 VAL 228
>sp|Q9YQ08|RDRP_TMVB Replicase large subunit OS=Tobacco mosaic
virus (strain B935A) OX=138309 PE=3 SV=1
Length=1616
Score = 38.9 bits (89), Expect = 2.9, Method: Composition-based stats.
Identities = 69/406 (17%), Positives = 123/406 (30%), Gaps = 73/406 (18%)
Query 5595 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5654
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFDED---LILVPGKQAAEMIRRRA------NSS 872
Query 5655 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNAR 5714
I+ + V+ D F +N + DE M ++ + A
Sbjct 873 GIIVATKDNVKTVDSFMMNFGKST----------RCQFKRLFIDEGLMLHTGCVNFLVAM 922
Query 5715 LRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVD 5774
+ GD Q+P + G P +F + + T RCPA++
Sbjct 923 SLCEIAYVYGDTQQIPYINRV--SGFPYPAHFAKL-----EVDEVETRRTTLRCPADVTH 975
Query 5775 TVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5834
++ Y+ + + + G + S + +I LT + ++A+
Sbjct 976 YLNRR-YEGFVMSTSSVKKSVSQEMVGGAAVINPISKPSHGKI------LTFTQSDKEAL 1028
Query 5835 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC---NVNRFNVAITR 5891
Y+ TV QG Y V + T T S + VA++R
Sbjct 1029 LSRGYS------------DVHTVHEVQGETYSDVSLVRLTPTPVSIIAGDSPHVLVALSR 1076
Query 5892 AKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTH 5951
L++ ++ + E ++ D KV G
Sbjct 1077 HTCS-------------LKYYTVVMDPLVSIIRDLEKLSSYLSDMYKVDAG-----TQXQ 1118
Query 5952 LSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
L +D+ FK L V P IS M F + + G M
Sbjct 1119 LQIDSVFKGSNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTM 1157
>sp|Q12019|MDN1_YEAST Midasin OS=Saccharomyces cerevisiae (strain
ATCC 204508 / S288c) OX=559292 GN=MDN1 PE=1 SV=1
Length=4910
Score = 38.9 bits (89), Expect = 3.0, Method: Composition-based stats.
Identities = 23/89 (26%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Query 926 PPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQ 985
P D ++EE E+EE + + E E+D G + G T AL EE EED +D +
Sbjct 4279 PDDLNKEEVGNEDEEVKQESGIESDNENDEPGPEEDAGETETALDEEEGAEED-VDMTND 4337
Query 986 QTVGQQDGSEDNQTTTIQTIVEVQPQLEM 1014
+ ++ + Q + + ++ +E
Sbjct 4338 EGKEDEENGPEEQAMSDEEELKQDAAMEE 4366
>sp|B3PRF6|ATP6_RHIE6 ATP synthase subunit a OS=Rhizobium etli
(strain CIAT 652) OX=491916 GN=atpB PE=3 SV=1
Length=250
Score = 37.7 bits (86), Expect = 3.1, Method: Composition-based stats.
Identities = 19/92 (21%), Positives = 37/92 (40%), Gaps = 9/92 (10%)
Query 3583 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMM-FVKHKHAFLCLF-- 3639
L+ ++ +L + FF + + FA+ I+ + + F KH FL +F
Sbjct 87 LVFSLFMFVLTANLLGMFPYFFTVTSQIIVTFALAILVIGTVLVYGFYKHGFHFLNVFVP 146
Query 3640 ------LLPSLATVAYFNMVYMPASWVMRIMT 3665
LLP + + + + P S +R+
Sbjct 147 SGVPGILLPLVVAIEIISFLSRPISLSVRLFA 178
>sp|Q9WAL8|POL1_SDVS5 RNA1 polyprotein OS=Satsuma dwarf virus
(isolate Satsuma mandarin/Japan/S-58/1977) OX=650481 PE=3 SV=1
Length=2081
Score = 38.5 bits (88), Expect = 3.2, Method: Composition-based stats.
Identities = 26/119 (22%), Positives = 42/119 (35%), Gaps = 6/119 (5%)
Query 4971 IAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVL 5030
+ A +G + + W +L + DY D + P R++ ++
Sbjct 1649 MVAHDELPSKVGINVYSESWDRLLGRHTRLANHFT---GDYSGFDTSTP---RVLVYAII 1702
Query 5031 ARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNIC 5089
+ + N VL+ ++ G LY GGT SG A T NSV N
Sbjct 1703 DKINELADDGEVNQRTRRNIIRFVLNRYLISDGVLYEIHGGTPSGFAPTVMINSVVNEF 1761
>sp|Q8IRB5|CLSPN_DROME Claspin OS=Drosophila melanogaster OX=7227
GN=Claspin PE=1 SV=1
Length=1465
Score = 38.5 bits (88), Expect = 3.2, Method: Composition-based stats.
Identities = 20/89 (22%), Positives = 37/89 (42%), Gaps = 6/89 (7%)
Query 929 EDEEEGDCEEEEFEPST-----QYEYGTEDDYQGKPLEFGATS-AALQPEEEQEEDWLDD 982
EDEEEG +EE+EP + +++ K A + + + +ED D+
Sbjct 861 EDEEEGMDVDEEYEPEDKPGYAEVTINEDEEIIDKVDSTAEDDGDAEENKNDADEDPEDN 920
Query 983 DSQQTVGQQDGSEDNQTTTIQTIVEVQPQ 1011
+ + +++ SE Q E Q +
Sbjct 921 PVEDSEDEKNDSESEQECEANPEPETQTR 949
>sp|Q1MKT2|ATP6_RHIJ3 ATP synthase subunit a OS=Rhizobium johnstonii
(strain DSM 114642 / LMG 32736 / 3841) OX=216596 GN=atpB
PE=3 SV=1
Length=250
Score = 37.7 bits (86), Expect = 3.3, Method: Composition-based stats.
Identities = 19/92 (21%), Positives = 37/92 (40%), Gaps = 9/92 (10%)
Query 3583 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMM-FVKHKHAFLCLF-- 3639
L+ ++ +L + FF + + A+ I+ + + F KH FL +F
Sbjct 87 LVFSLFMFVLTANLLGMFPYFFTVTSQIIVTAALAILVIGTVVVYGFYKHGFKFLNVFVP 146
Query 3640 ------LLPSLATVAYFNMVYMPASWVMRIMT 3665
LLP + T+ + + P S +R+
Sbjct 147 SGVPGILLPLVVTIEIISFLSRPISLSVRLFA 178
>sp|P12428|BROWN_DROME Protein brown OS=Drosophila melanogaster
OX=7227 GN=bw PE=1 SV=1
Length=675
Score = 38.5 bits (88), Expect = 3.3, Method: Composition-based stats.
Identities = 18/95 (19%), Positives = 36/95 (38%), Gaps = 1/95 (1%)
Query 3039 GALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVY 3098
+S ++ + A + RR GE ++ ++ + ++SF + Y
Sbjct 454 SIFMLSNEMIFTFSYGVTYIFPAALPI-IRREVGEGTYSLSAYYVALVLSFVPVAFFKGY 512
Query 3099 SFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFT 3133
FL +Y+ IY F L + FL + +
Sbjct 513 VFLSVIYASIYYTRGFLLYLSMGFLMSLSAVAAVG 547
>sp|B5ZS16|ATP6_RHILW ATP synthase subunit a OS=Rhizobium leguminosarum
bv. trifolii (strain WSM2304) OX=395492 GN=atpB PE=3
SV=1
Length=250
Score = 37.4 bits (85), Expect = 3.5, Method: Composition-based stats.
Identities = 19/92 (21%), Positives = 38/92 (41%), Gaps = 9/92 (10%)
Query 3583 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMM-FVKHKHAFLCLF-- 3639
L+ ++ +L + FF + + FA+ I+ + + F KH FL +F
Sbjct 87 LVFSLFMFVLTANLLGMFPYFFTITSQIIVTFALAILVIGTVLVYGFYKHGFHFLNVFVP 146
Query 3640 ------LLPSLATVAYFNMVYMPASWVMRIMT 3665
LLP + ++ + + P S +R+
Sbjct 147 SGVPGILLPLVVSIEIISFLSRPISLSVRLFA 178
>sp|B9JA28|ATP6_RHIR8 ATP synthase subunit a OS=Rhizobium rhizogenes
(strain K84 / ATCC BAA-868) OX=311403 GN=atpB PE=3 SV=1
Length=250
Score = 37.4 bits (85), Expect = 3.5, Method: Composition-based stats.
Identities = 21/101 (21%), Positives = 40/101 (40%), Gaps = 13/101 (13%)
Query 3578 GTHHWLLLTILTSLLVLVQST----QWSLFFFLYENAFLPFAMGIIAMSAFAMM-FVKHK 3632
GT ++ SL + V + F+ + + FA+ ++ + + F+KH
Sbjct 78 GTKGMKFFPLVFSLFMFVLTANLLGMVPYFYTVTSQIIVTFALALLVILTVILYGFIKHG 137
Query 3633 HAFLCLF--------LLPSLATVAYFNMVYMPASWVMRIMT 3665
FL LF LLP + + + + P S +R+
Sbjct 138 FGFLKLFVPQGVPGILLPLVVIIEIISFLSRPISLSVRLFA 178
>sp|C3MGQ4|RLME_SINFN Ribosomal RNA large subunit methyltransferase
E OS=Sinorhizobium fredii (strain NBRC 101917 / NGR234)
OX=394 GN=rlmE PE=3 SV=1
Length=245
Score = 37.4 bits (85), Expect = 4.2, Method: Composition-based stats.
Identities = 22/95 (23%), Positives = 35/95 (37%), Gaps = 2/95 (2%)
Query 6922 WDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNAD-LYK 6980
DL++SDM P T + ++ F LA GG K + D L
Sbjct 138 PDLVLSDMAAPTTGHRQTDHLRTMHLCEVAAHFAVDVLAKGGHFLAKTFQGGTERDLLNM 197
Query 6981 LMGHFAWW-TAFVTNVNASSSEAFLIGCNYLGKPR 7014
L +F+ + S E FL+ + G+ +
Sbjct 198 LKQNFSQVIHVKPASSRTESVEMFLLAKGFKGRRK 232
>sp|Q67704|RDRP_GVAIS RNA replication protein OS=Grapevine virus
A (isolate Is 151) OX=651358 GN=ORF1 PE=3 SV=1
Length=1707
Score = 38.1 bits (87), Expect = 4.5, Method: Composition-based stats.
Identities = 34/175 (19%), Positives = 62/175 (35%), Gaps = 36/175 (21%)
Query 5599 QKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5658
++ T G G+GKSH+ C+ LK+ ++K I
Sbjct 920 KEVLTAFGFAGSGKSHW--------------------------CQTILKHCSVEKVLVIS 953
Query 5659 PARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK 5718
P + + + K++ F V + + +V DEI + + +V A + +
Sbjct 954 PRKVLRDDW-VAKISKKHRVVTF-EVAFMDDYGCKDIVIDEIGLLPPGYIDLVIAAHQPR 1011
Query 5719 HYVYIGDPAQ--LPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAE 5771
V +GDP Q + R + + + FN V + +L R P
Sbjct 1012 TLVLLGDPLQSTYHSKRDNVVLEASQEDVFNRVRGKLP------YLCYSHRLPRN 1060
>sp|A5N5W0|PANB_CLOK5 3-methyl-2-oxobutanoate hydroxymethyltransferase
OS=Clostridium kluyveri (strain ATCC 8527 / DSM 555
/ NCIMB 10680) OX=431943 GN=panB PE=3 SV=1
Length=280
Score = 37.4 bits (85), Expect = 4.6, Method: Composition-based stats.
Identities = 28/173 (16%), Positives = 64/173 (37%), Gaps = 11/173 (6%)
Query 1070 GVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQ 1129
G+AGA+ ++ + + P+ +G + ++V G +G+D
Sbjct 108 GLAGAVKLEGGVSVYEQVKAIVKAQIPV-MGHIGLTP------QSVNVFGGFKVQGKDES 160
Query 1130 LLKSAYENFNQHEVL-LAPLLSAGI-FGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLV 1187
K+ E+ + E ++ GI + I + V + T+ + L + +
Sbjct 161 KAKNIIEDAKRLEEAGAFSIVLEGIPYKLAKIITETVSIPTIGIGAGKYCDGQILVYQDM 220
Query 1188 SSFLEMKSEKQVEQ--KIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEE 1238
K V+ E+ ++ K +ITE K + ++ K+ + +
Sbjct 221 LGLFSDFKPKFVKSYGNAGEVIRKAFKDYITEVKEGIFPDEEYSFKMDDSIID 273
>sp|P0DW67|RGYR2_SULAC Reverse gyrase 2 OS=Sulfolobus acidocaldarius
(strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157
/ NCIMB 11770) OX=330779 GN=rgy2 PE=2 SV=1
Length=1153
Score = 37.7 bits (86), Expect = 4.9, Method: Composition-based stats.
Identities = 25/144 (17%), Positives = 57/144 (40%), Gaps = 19/144 (13%)
Query 5569 HYVRITGLYPTLNISDEFSSNVANYQKV------GMQKY---STLQG-------PPGTGK 5612
Y + G + + + ++K+ +Q+Y ++G P G GK
Sbjct 50 KYSTLKGYSELYMDLEMYDDILRLFKKIVGGEPWSLQRYWLNKLVRGESFSLSAPTGVGK 109
Query 5613 SHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKV 5672
+ I ++Y + ++ + + D +CEK K + C++ P +V +
Sbjct 110 TTTLIVYSVYSHTTS-LFVVPTKSLRDQICEKLKKIGHLVSCNK--PEEDKVNVVTFHSI 166
Query 5673 NSTLEQYVFCTVNALPETTADIVV 5696
N ++++V L AD+++
Sbjct 167 NKNIDEFVRIKPKLLMVDDADMIL 190
>sp|A5E287|POA1_LODEL ADP-ribose 1''-phosphate phosphatase OS=Lodderomyces
elongisporus (strain ATCC 11503 / CBS 2605 / JCM
1781 / NBRC 1676 / NRRL YB-4239) OX=379508 GN=POA1 PE=3 SV=1
Length=160
Score = 36.2 bits (82), Expect = 4.9, Method: Composition-based stats.
Identities = 40/159 (25%), Positives = 64/159 (40%), Gaps = 22/159 (14%)
Query 1038 VYIKNAD-IVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGP 1096
V D A K V+ +A N GGG+A + A + S +Y N
Sbjct 3 VKYIRGDLFTHSAPTGKSIVLAHACNTGGSWGGGIAAVFARKYPKANRQYS-EYCHKNSH 61
Query 1097 LKVGGSCVLSGHNLAK-----HCLHVV----GP-------NVNKGEDIQLLKSA-YENFN 1139
L +G S +L + K CL P + + E + LKS E N
Sbjct 62 L-LGTSLLLKADDYDKSKAYIACLFTSDFNQSPEQIVKYTDQSLQELAKQLKSLPIETQN 120
Query 1140 QHEVLLAPLLSAGIFGADPIHSLRVC--VDTVRTNVYLA 1176
++V+ P +++GIFG ++ V +D++ NVY+
Sbjct 121 GNQVVNMPKINSGIFGVPWENTEAVLDKLDSLDFNVYVI 159
>sp|P14565|TRAI1_ECOLI Multifunctional conjugation protein TraI
OS=Escherichia coli (strain K12) OX=83333 GN=traI PE=1 SV=2
Length=1756
Score = 37.7 bits (86), Expect = 5.2, Method: Composition-based stats.
Identities = 28/140 (20%), Positives = 45/140 (32%), Gaps = 28/140 (20%)
Query 5600 KYSTLQGPPGTGKSH------FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDK 5653
+++ +QG G GK+ A+ + R+V +H AV + + +
Sbjct 986 RFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAVGEMRSAGVDAQTLAS 1045
Query 5654 CSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNA 5713
+ R F N L + DE SM N D++ A
Sbjct 1046 FLHDTQLQQRSGETPDFS-------------NTL-------FLLDESSMVGNTDMARAYA 1085
Query 5714 RL--RAKHYVYIGDPAQLPA 5731
+ V GD QL A
Sbjct 1086 LIAAGGGRAVASGDTDQLQA 1105
>sp|Q68XQ1|ATP6_RICTY ATP synthase subunit a OS=Rickettsia typhi
(strain ATCC VR-144 / Wilmington) OX=257363 GN=atpB PE=3
SV=1
Length=242
Score = 37.0 bits (84), Expect = 5.2, Method: Composition-based stats.
Identities = 17/92 (18%), Positives = 35/92 (38%), Gaps = 9/92 (10%)
Query 3583 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMM-FVKHKHAFLCLF-- 3639
L+ ++ +L F + + F + ++ ++ F+KH +FL LF
Sbjct 87 LVFSLFIFILFCNLLGMTPYSFTATSHIIVTFTLALLIFLTVTIVGFIKHGMSFLTLFLP 146
Query 3640 ------LLPSLATVAYFNMVYMPASWVMRIMT 3665
L P + + F + P S +R+
Sbjct 147 QGTPVWLAPLMIVIELFTYLAKPVSLSLRLAA 178
>sp|Q7VQM8|RLME_BLOFL Ribosomal RNA large subunit methyltransferase
E OS=Blochmannia floridanus OX=203907 GN=rlmE PE=3 SV=1
Length=206
Score = 36.6 bits (83), Expect = 5.2, Method: Composition-based stats.
Identities = 38/153 (25%), Positives = 66/153 (43%), Gaps = 18/153 (12%)
Query 6873 DKGVAPG---TAVLRQWLPTGTLLVDSDLNDFVSDADSTLI-GDCATVHTANKWDL---- 6924
D G PG + V++Q GT+ V D+ A + GDC+ ++ N+ DL
Sbjct 49 DLGSTPGGWSSYVIKQISNLGTI-VSCDILPMKKIAGVKFLQGDCSNINFLNEIDLKIKH 107
Query 6925 -----IISDMYDPKTKNVTKENDSKEGFFTYI-CGFIQQKLALGGSVAIKITE-HSWNAD 6977
++SDM P T ++ + K + I + LA GGS +KI + ++
Sbjct 108 KRAQVVLSDM-SPNTTGISTVDVCKSIYLGKIALNMCCRFLAPGGSFLVKIFQGDGFDQY 166
Query 6978 LYKLMGHFAWWTAFVTNVNAS-SSEAFLIGCNY 7009
LY L F + + S S E +++ ++
Sbjct 167 LYNLKCLFHKVKVRKPSSSRSHSREVYIVSKDF 199
>sp|O94500|NDUV1_SCHPO NADH-ubiquinone oxidoreductase 51 kDa subunit
homolog SPBC18E5.10, mitochondrial OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=SPBC18E5.10
PE=3 SV=1
Length=452
Score = 37.4 bits (85), Expect = 5.5, Method: Composition-based stats.
Identities = 46/263 (17%), Positives = 87/263 (33%), Gaps = 42/263 (16%)
Query 991 QDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAK 1050
D D + + I++ P +EL + G+ + + A E +
Sbjct 47 DDALADGEYENLSEILKYDPLNIIELVQE-SELRGRGRYGFPTGEKMLSLYKATSSERGR 105
Query 1051 KVKPTVVVNAANVY---------LKH------GGGV--AGALNKATNNAMQV---ESDDY 1090
K KP V+VNAA L+H G + A A+ + +
Sbjct 106 KEKPVVIVNAAENDIGSFKDRLLLRHEPHKIIEGAIIAARAVEASACYLFIRKDYYEETV 165
Query 1091 IATNGPLKVGGSCVLSGHNLAKHC-----LHVVGPNVNK---GEDIQLLKSAYENFNQHE 1142
+ ++ +L + L +H P GE+ L++S F +
Sbjct 166 MMQKCIIQAYAKKLLGKNLLGTSIGLELLIH---PGAGSYITGEESALIQSLQGEFPVPD 222
Query 1143 VLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQK 1202
+ + +++G+FG T+ NV + K F+ M K
Sbjct 223 IPINNTITSGLFGLP----------TLVLNVETVSNLPAIIKKGPKFFISMGRPNNRGTK 272
Query 1203 IAEIPKEEVKPFITESKPSVEQR 1225
+ I E +P + E+ S+ +
Sbjct 273 LFSISGEVNEPNVIEACMSIPLK 295
>sp|Q66121|1A_CMVIX Replication protein 1a OS=Cucumber mosaic
virus (strain Ixora) OX=117114 GN=ORF1a PE=3 SV=1
Length=993
Score = 37.7 bits (86), Expect = 5.7, Method: Composition-based stats.
Identities = 56/296 (19%), Positives = 101/296 (34%), Gaps = 43/296 (15%)
Query 5604 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5663
+ G G GK+ +++ PS +V TA +A + K + +
Sbjct 712 VDGVAGCGKTTAI--KSIFEPSTDMVVTANKKSA-QDVRMALFKSSDSKEACTFVRTADS 768
Query 5664 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5723
V +N P + V+ DE+ + L V ++L+A +
Sbjct 769 V------------------LLNECPTVSR--VLVDEVVLLHFGQLCAVMSKLKAVRAICF 808
Query 5724 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5783
GD Q + + + + +++ D T R P ++V V +
Sbjct 809 GDSEQ-------IAFSSRDASFDMRFSKIIPDETSDA--DTTFRSPQDVVPLVRLMA--T 857
Query 5784 KLKA---HKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYN 5840
K H + + K +T S++ + R ++T A + A IS
Sbjct 858 KALPRGTHSKYTKWVSQSKVKRSVTSRAISSVTLVDLDSSRFYITMTQADK-ASLISRAK 916
Query 5841 SQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN---VAITRAK 5893
N + +TV SQG D+V + T +F+ VA+TR K
Sbjct 917 EMN-LPKTFWNERIKTVHESQGISEDHVTLVRLKSTKCDL-FKQFSYCLVALTRHK 970
>sp|Q54VA8|TRM7_DICDI Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase
OS=Dictyostelium discoideum OX=44689
GN=fsjA PE=3 SV=1
Length=270
Score = 37.0 bits (84), Expect = 5.7, Method: Composition-based stats.
Identities = 33/152 (22%), Positives = 54/152 (36%), Gaps = 19/152 (13%)
Query 6877 APGT--AVLRQWL-----PTGTLLVDSDLNDFVS-DADSTLIGDCATVHTANKW------ 6922
APG+ VL + + +V DL + + GD T+ +
Sbjct 51 APGSWSQVLSRRIYGDGKDPDVKIVAVDLQEMAPLKGVVQIKGDITKYETSKQIISHFDG 110
Query 6923 ---DLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLY 6979
DLIISD T + + L +GG+ K+ + + +Y
Sbjct 111 SLADLIISDGAPDVTGLHDIDFYGQSQLILSALNITTHTLKIGGTFVAKMFKGDDMSLMY 170
Query 6980 KLMGHFAWWTAFV--TNVNASSSEAFLIGCNY 7009
M F +FV ++ SS E F++ NY
Sbjct 171 SQMKLFFEHVSFVKPSSSRESSLENFILCRNY 202
>sp|P90211|RDRP_TMOB Replicase large subunit OS=Tobamovirus Ob
OX=31749 PE=3 SV=1
Length=1616
Score = 37.7 bits (86), Expect = 6.0, Method: Composition-based stats.
Identities = 45/302 (15%), Positives = 79/302 (26%), Gaps = 48/302 (16%)
Query 5596 VGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS 5655
V K + + G PG GK+ + + V A+ ++
Sbjct 822 VSSAKVTLVDGVPGCGKTKEILRRVNFSEDL---------VLVPGKEAAAMIRKRANQSG 872
Query 5656 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5715
I+ V+ D F +N + P + DE M + +
Sbjct 873 NIVANNDNVKTVDSFLMN----------LGKGPVCQFKRLFVDEGLMLHPGCVYFLVKLS 922
Query 5716 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5775
GD Q+P + +L+ T RCP ++
Sbjct 923 LCNEAFVFGDTQQIPYIN-----RVQNFPFPQHFSKLIVDETEKR--RTTLRCPVDVTHF 975
Query 5776 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVF 5835
++ YD + G +A+ P ++ + K
Sbjct 976 LN-QCYDGAVTTTSKTQRSVGLEVVGG-------AAVMNPVTKPLKGKIVTFTQSDKLTM 1027
Query 5836 ISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR---FNVAITRA 5892
+S + TV QG Y+ V + T T V +TR
Sbjct 1028 LS----RGYQ-------DVNTVHEIQGETYEEVSLVRLTPTPIHIISRESPHVLVGLTRH 1076
Query 5893 KV 5894
Sbjct 1077 TR 1078
>sp|Q58990|Y1595_METJA UPF0104 membrane protein MJ1595 OS=Methanocaldococcus
jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1
/ JCM 10045 / NBRC 100440) OX=243232 GN=MJ1595 PE=3 SV=1
Length=336
Score = 37.0 bits (84), Expect = 6.1, Method: Composition-based stats.
Identities = 33/250 (13%), Positives = 78/250 (31%), Gaps = 11/250 (4%)
Query 2129 AVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNS 2188
+N+ P I + L V+ + + N+ F +L+ L F +
Sbjct 36 LINTNPEYVILAFILQILVSVILSARWKFIIKILGYSANFKNIFLLVLMGL--FINNITP 93
Query 2189 RIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYST- 2247
++ A + K + ++++ I+ +G + +
Sbjct 94 SMRGGGEAFRAYY----LSKLEEIPKGLAFSTVVVERVLDTAIFLFFTLFVIGYFVVTGF 149
Query 2248 -AALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLET 2306
+++S + + S N + C C D L++
Sbjct 150 KYLEYLILSWIFLFSLTAIIIYLIANKGLLIKTVTKISKFICKYCSYNYDET---KILQS 206
Query 2307 IQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMW 2366
I+ +S K+ G + + F +L L + +V +S +L+
Sbjct 207 IEEFYNSMKFFKNKRGWEVVVAIFLSVMRYIFDILKLWLLFLSLSYVVSVICVSAVYLIT 266
Query 2367 LIINLVQMAP 2376
L+ ++ + P
Sbjct 267 LLSGVLSITP 276
>sp|B5RRC2|MRAY_BORRA Phospho-N-acetylmuramoyl-pentapeptide-transferase
OS=Borrelia recurrentis (strain A1) OX=412418 GN=mraY
PE=3 SV=1
Length=351
Score = 37.0 bits (84), Expect = 6.1, Method: Composition-based stats.
Identities = 34/240 (14%), Positives = 79/240 (33%), Gaps = 15/240 (6%)
Query 3574 RTIKGTHHWLLLTILTSLLVLVQSTQWSL---------FFFLYENAFLPFAMGIIAMSAF 3624
RT T LL ++ ++ + + L L E +P G++
Sbjct 16 RTAYATIFAFLLALIFGPFIISRLKKLKLDQILRKDGPKHHLSEKMGIPTMGGVLIFFCV 75
Query 3625 AMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
+ H F FL+ V++ + + ++ D ++ FK+ ++
Sbjct 76 LVSLFFWIHFFNIYFLIVLFVMVSFACLGFTDDLLKIKRKN-SDGLNP---KFKIYGQIL 131
Query 3685 YASAVVLLILMTARTVYDDGARRVWTLMNV-LTLVYKVYYGNALDQAISMWALIISVTSN 3743
++ V+++ + + + L ++Y + L A + + L +
Sbjct 132 FSFISVVMLYYFGGEHVSILYFPFFKSLKLDLGILYIPFGMFVLISASNSFNLTDGLDGL 191
Query 3744 YSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
G+ V+ I ++ ++ ++ + FLG FG N Y
Sbjct 192 AIGLSIVVIGALIIIAYLTSRVDFALYLNIPNVKGCEELVIFLGALLGGSFGFL-WFNAY 250
>sp|P14879|PYR4_MICDP Phycobilisome 31.6 kDa linker polypeptide,
phycocyanin-associated, rod OS=Microchaete diplosiphon OX=1197
GN=cpcI3 PE=3 SV=1
Length=285
Score = 37.0 bits (84), Expect = 6.2, Method: Composition-based stats.
Identities = 20/85 (24%), Positives = 37/85 (44%), Gaps = 4/85 (5%)
Query 5100 LSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFN 5159
L T+GN ++VR L LY+++ +F + KH D++ + ++
Sbjct 61 LLTNGNITVQEFVRQLAK---SNLYKSKFFSNNFHSRVTELNFKHLLGRAPYDESEIIYH 117
Query 5160 ST-YASQGLVASIKNFKSVLYYQNN 5183
Y ++G A I ++ YQ N
Sbjct 118 LDLYQTKGYEADIDSYIDSAEYQTN 142
>sp|Q6CRE9|FYV8_KLULA Protein FYV8 OS=Kluyveromyces lactis (strain
ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140
/ WM37) OX=284590 GN=FYV8 PE=3 SV=2
Length=806
Score = 37.4 bits (85), Expect = 6.5, Method: Composition-based stats.
Identities = 24/146 (16%), Positives = 53/146 (36%), Gaps = 8/146 (5%)
Query 875 VADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEG 934
V D + + +S+ +T D++ S ++ E K++ Y + Y DED ++
Sbjct 86 VNDDLDSLMHQISQEMTAKDEDVNNTSDPED---EDDAELKVSKTGYFAAYVNDEDTDDR 142
Query 935 DCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGS 994
+ + + E + E TE + A + ++ E E + Q
Sbjct 143 ESVKSDIESAKLAESATEINKTD-----NAKAESVSEVESVAESVKRAKVEVEPVQIVNV 197
Query 995 EDNQTTTIQTIVEVQPQLEMELTPVV 1020
+ + E + ++E+ P
Sbjct 198 GEESFKGDDSEAESVKRADVEVEPFK 223
>sp|P30738|RDRP_TMVKR Replicase large subunit OS=Tobacco mosaic
virus (strain Korean NC 82) OX=31746 PE=3 SV=2
Length=1616
Score = 37.7 bits (86), Expect = 6.5, Method: Composition-based stats.
Identities = 68/410 (17%), Positives = 124/410 (30%), Gaps = 81/410 (20%)
Query 5595 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5654
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFDED---LILVPGKQAAEMIRRRA------NSS 872
Query 5655 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM----ATNYDLSV 5710
I+ + V+ D F +N + DE M N+ +++
Sbjct 873 GIIVATKDNVKTVDSFMMNFGKST----------RCQFKRLFIDEGLMLHTGCVNFLVTM 922
Query 5711 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5770
+ + GD Q+P + G P +F + + T RCPA
Sbjct 923 SLCEIAYVY----GDTQQIPYINRV--SGFPYPAHFAKL-----EVDEVETRRTTLRCPA 971
Query 5771 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5830
++ ++ Y+ + + + G + S + + LT +
Sbjct 972 DVTHYLNRR-YEGFVMSTSSVKKSVSQEMVGGAAVINPISK------PLHGKILTFTQSD 1024
Query 5831 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC---NVNRFNV 5887
++A+ Y+ TV QG Y V + T T S + V
Sbjct 1025 KEALLSRGYS------------DVHTVHEVQGETYSDVSLVRLTPTPVSIIAGDSPHVLV 1072
Query 5888 AITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQ 5947
A++R L++ ++ + E ++ D KV G
Sbjct 1073 ALSRHTCS-------------LKYYTVVMDPLVSIIRDLEKLSSYLLDMYKVDAG----- 1114
Query 5948 APTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
L +D+ FK L V P IS M F + + G M
Sbjct 1115 TQXQLQIDSVFKGSNLFVATPKTGD-------ISDMQFYYDKCLPGNSTM 1157
>sp|Q65674|TGB1_BNYVS Movement protein TGB1 OS=Beet necrotic yellow
vein virus (isolate Japan/S) OX=652670 GN=ORF4 PE=3 SV=1
Length=384
Score = 37.0 bits (84), Expect = 6.6, Method: Composition-based stats.
Identities = 47/308 (15%), Positives = 95/308 (31%), Gaps = 78/308 (25%)
Query 5600 KYSTLQGPPGTGKSHFAIGL-ALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5658
+ + G PG GKS L + ++V ++ + L +D
Sbjct 117 RVGIVLGAPGVGKSTSIKNLLDKFGAKHKMVLCLPFSQLLEGVFAGRLDTFLVDD----- 171
Query 5659 PARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK 5718
+FC ++ + ++ DE++ ++ V+ L K
Sbjct 172 ---------------------LFC--RSVGYGKYNTMLVDEVTRVHMCEILVLAGHLGVK 208
Query 5719 HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSA 5778
+ + GDPAQ L +N ++ G A+++++ +
Sbjct 209 NVICFGDPAQ------GLNYKAGSAVNYN--FPIIAECYASRRFGK---ATADLINSSNG 257
Query 5779 ----LVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5834
+V +N++K C K+ V
Sbjct 258 GGKPVVGNNEVKDSWTFEELCGKIL------------------------------DMSTV 287
Query 5835 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYV--IFTQTTETAHSCNVNRFNVAITRA 5892
++ +Q + + + + G YD V I + A C+ N V +TRA
Sbjct 288 LVATRETQKFLLED--NIESILYSDAHGQTYDVVTIILEDEFDDAAICDPNVRAVLLTRA 345
Query 5893 KVGILCIM 5900
+ G + M
Sbjct 346 RKGGMIKM 353
>sp|A0A0S2T050|RDRP_TBRFV Replicase large subunit OS=Tomato brown
rugose fruit virus (isolate TOBRFV/Tomato/Jordan/Tom1-Jo/2015)
OX=2654645 PE=3 SV=1
Length=1615
Score = 37.4 bits (85), Expect = 6.7, Method: Composition-based stats.
Identities = 74/410 (18%), Positives = 122/410 (30%), Gaps = 81/410 (20%)
Query 5595 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5654
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSKVNFEED---LILVPGKQAAEMIKRRA------NAS 872
Query 5655 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM----ATNYDLSV 5710
I R V D F +N Y T + DE M N+ +S+
Sbjct 873 GIIQATRDNVRTVDSFIMN-----YGKGT-----RCQFKRLFIDEGLMLHTGCVNFLVSM 922
Query 5711 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5770
+ + GD Q+P + G P +F + + T RCPA
Sbjct 923 SLCEIAYVY----GDTQQIPYINRV--SGFPYPAHFAKI-----EVDEVETRRTTLRCPA 971
Query 5771 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5830
+I ++ Y+ + + G + S ++ LT +
Sbjct 972 DITHYLNRR-YEGYVMCTSSVKKSVSQEMVSGAAMINPVSKPLNGKV------LTFTQSD 1024
Query 5831 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC---NVNRFNV 5887
++A+ Y TV QG Y V + T T S + V
Sbjct 1025 KEALLSRGYT------------DVHTVHEVQGETYADVSLVRLTPTPVSIIAGDSPHVLV 1072
Query 5888 AITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQ 5947
A++R L++ ++ + E ++ D KV G
Sbjct 1073 ALSRHT-------------QTLKYYTVVMDPLVSIIRDLEKLSSYLLDMYKVDAG----- 1114
Query 5948 APTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
L VD+ FK L V P IS M F + + G M
Sbjct 1115 TQXQLQVDSVFKGSNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTM 1157
>sp|Q67ES1|TR113_RAT Taste receptor type 2 member 113 OS=Rattus
norvegicus OX=10116 GN=Tas2r113 PE=3 SV=1
Length=309
Score = 36.6 bits (83), Expect = 7.1, Method: Composition-based stats.
Identities = 26/215 (12%), Positives = 67/215 (31%), Gaps = 31/215 (14%)
Query 2211 LEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGY 2270
L ++++ S + I+ + + L L++ + VL L Y
Sbjct 29 LMTCIDWVRRRKISLVDQILTALAITRITLILLVFIDWWVSVLFPALHET---GKILRMY 85
Query 2271 LNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLA 2330
+ T+ +C + S+ + + ++ S+ + + +
Sbjct 86 --FISWTVINHCNLWLTASLSIIYFLKIASFSSIIFL------------YLKFRVKNVVF 131
Query 2331 YILFTRFFYVLGLAAIMQLFFSYFAVHFISNSW-------------LMWLIINLVQMAPI 2377
L F++ AI+ ++F N + + P
Sbjct 132 VTLLVSLFFLFINTAIVNVYFDVCFDGVQRNVSQVSRLYNHEQICKFLSFTNPMFAFIPF 191
Query 2378 -SAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMM 2411
++M ++ S + K+ H +GC + ++
Sbjct 192 VTSMATFFLLIFSLWRHLKNMKHNAEGCRDVSTIV 226
>sp|A8GLV8|ATP6_RICAH ATP synthase subunit a OS=Rickettsia akari
(strain Hartford) OX=293614 GN=atpB PE=3 SV=1
Length=242
Score = 36.6 bits (83), Expect = 7.2, Method: Composition-based stats.
Identities = 21/95 (22%), Positives = 36/95 (38%), Gaps = 13/95 (14%)
Query 3584 LLTILTSLLVLVQSTQW----SLFFFLYENAFLPFAMGIIAMSAFAMM-FVKHKHAFLCL 3638
+ ++ SL + V + F + + F + II ++ FVKH FL L
Sbjct 84 FIPLVFSLFIFVLFSNLLGMTPYSFTATSHIIVTFTLAIIVFLTVTIVGFVKHGLRFLTL 143
Query 3639 F--------LLPSLATVAYFNMVYMPASWVMRIMT 3665
F L P + + F + P S +R+
Sbjct 144 FLPYGTPLWLAPLMIVIELFTYLAKPVSLSLRLAA 178
>sp|Q04574|POL1_BAYMG Genome polyprotein 1 OS=Barley yellow mosaic
virus (isolate Germany) OX=31728 PE=3 SV=1
Length=2412
Score = 37.4 bits (85), Expect = 7.6, Method: Composition-based stats.
Identities = 61/356 (17%), Positives = 117/356 (33%), Gaps = 50/356 (14%)
Query 4808 NKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPT---MCDIRQLLFV 4864
N D YDF F ++ +A D +YN + +L
Sbjct 1651 NDDVYDFMREHPTFTWLKDFMNEYAPSVLSYSAYYKDLC--KYNRAKHVLTYNPEELHCA 1708
Query 4865 VEVVDKYFD--CYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAY 4922
+ + K + G + Q +V+++ + + GK R +S ++ L
Sbjct 1709 TKGLIKMLEDAGLTQGSVRTPQQVVSDIQWNTSAGPSYQGKKRDLCAHLSDDEVLHLAEV 1768
Query 4923 TKRNVIPTITQMNLKYAISAKNRARTVAGVS------ICSTMTNRQFHQKLL------KS 4970
++ + + + S K RT+ V ++ F K K
Sbjct 1769 CRQQFLEGKSTGV--WNGSLKAELRTIEKVEAEKTRVFTASPITSLFAMKFYVDDFNKKF 1826
Query 4971 IAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGW-----DYPKCDRAM-PNMLRI 5024
A A +G +KF GW ++ + P GW D + D ++ P +
Sbjct 1827 YATNLKAPHTVGINKFGRGWEK----LHDKLNRP---GWLHGSGDGSRFDSSIDPFFFDV 1879
Query 5025 MASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANS 5084
+ ++ RKH + +E + + + G + K G +SG +T N+
Sbjct 1880 VKTI---RKHFLPSEHHKAIDLIYDEILN--TTICLANGMVIRKNVGNNSGQPSTVVDNT 1934
Query 5085 VFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRD---VDTDFVNEF 5137
+ + A L +K D+ + L R + + + F EF
Sbjct 1935 L--------VLMTAFLYAYIHKTGDRELALLNERFIFVCNGDDNKFAISPQFDEEF 1982
>sp|P04540|NU5M_TRYBB NADH-ubiquinone oxidoreductase chain 5 OS=Trypanosoma
brucei brucei OX=5702 GN=ND5 PE=3 SV=1
Length=590
Score = 37.0 bits (84), Expect = 7.8, Method: Composition-based stats.
Identities = 22/187 (12%), Positives = 56/187 (30%), Gaps = 14/187 (7%)
Query 3618 IIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGF 3677
++ +M + + FL+ S+ Y+ + + WL V + F
Sbjct 25 FLSFWLSLVMIIFIVLCMIFSFLMVSVCLYGYYYYDFCLILMLDFCFIWLTYVCSGFYMF 84
Query 3678 KLKDCVMYASAVVLLILMTARTVYDDGA-----RRVWTLM-NVLTLVYKVYYGNALDQAI 3731
+ + ++ ++ + N+ L Y + +
Sbjct 85 IML-LINMVFCFIVFYAFYYMYFDMLLGRFLIIFWIFVVCMNLFILSYDFLTAYCGWELL 143
Query 3732 SMWALIISVTSNYSGVV----TTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLG 3787
+++ + Y F+ + + + I F++ M + FL
Sbjct 144 GLFSFFLISYFWYRFFALKFGFKAFFIGKIGDVLLIFAFSIIFLSNGF---CMTTFYFLN 200
Query 3788 YFCTCYF 3794
+FC Y+
Sbjct 201 FFCMDYY 207
>sp|Q98745|RDRP_TMVRA Replicase large subunit OS=Tobacco mosaic
virus (strain Rakkyo) OX=138310 PE=3 SV=1
Length=1616
Score = 37.4 bits (85), Expect = 7.8, Method: Composition-based stats.
Identities = 66/406 (16%), Positives = 118/406 (29%), Gaps = 73/406 (18%)
Query 5595 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5654
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSNAKVVLVDGVPGCGKTKEILSRVNFDED---LILVPGKQAAEMIRRRA------NSS 872
Query 5655 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNAR 5714
I+ + V D F +N + DE M ++ + A
Sbjct 873 GIIVATKDNVRTVDSFMMN----------FGKTTRCQFKRLFIDEGLMLHTGCVNFLVAM 922
Query 5715 LRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVD 5774
GD Q+P + S + + L RCPA++
Sbjct 923 SLCDVAYVYGDTQQIP---YINRVSGFPYPAHFSKLEVDEVETRRTTL----RCPADVTH 975
Query 5775 TVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5834
++ Y+ + + + G + S + + LT + ++A+
Sbjct 976 YLNRR-YEGFVVSTSSVKKSVSQEMVSGAAVINPISK------PLHGKILTFTQSDKEAL 1028
Query 5835 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC---NVNRFNVAITR 5891
Y+ TV QG Y V + T T S + VA++R
Sbjct 1029 LSRGYS------------EVHTVHEVQGETYSDVSLVRLTPTPISIIAGDSPHVLVALSR 1076
Query 5892 AKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTH 5951
L++ ++ + E ++ D KV G+
Sbjct 1077 HTCS-------------LKYYTVVMDPLVSIIRDLEKLSSYLLDMYKVDAGIQ-----XQ 1118
Query 5952 LSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
L +D+ FK L V P IS M F + + G M
Sbjct 1119 LQIDSVFKGSNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTM 1157
>sp|B5RLC9|MRAY_BORDL Phospho-N-acetylmuramoyl-pentapeptide-transferase
OS=Borrelia duttonii (strain Ly) OX=412419 GN=mraY
PE=3 SV=1
Length=351
Score = 36.6 bits (83), Expect = 8.1, Method: Composition-based stats.
Identities = 34/240 (14%), Positives = 79/240 (33%), Gaps = 15/240 (6%)
Query 3574 RTIKGTHHWLLLTILTSLLVLVQSTQWSL---------FFFLYENAFLPFAMGIIAMSAF 3624
RT T LL ++ ++ + + L L E +P G++
Sbjct 16 RTAYATIFAFLLALIFGPFIISRLKKLKLDQILRKDGPKRHLSEKMGIPTMGGVLIFFCV 75
Query 3625 AMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVM 3684
+ H F FL+ V++ + + ++ D ++ FK+ ++
Sbjct 76 LVSLFFWIHFFNIYFLIVLFVMVSFACLGFTDDLLKIKRKN-SDGLNP---KFKIYGQIL 131
Query 3685 YASAVVLLILMTARTVYDDGARRVWTLMNV-LTLVYKVYYGNALDQAISMWALIISVTSN 3743
++ V+++ + + + L ++Y + L A + + L +
Sbjct 132 FSFISVVMLYYFGGEHVSILYFPFFKSLKLDLGILYIPFGMFVLISASNSFNLTDGLDGL 191
Query 3744 YSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRY 3803
G+ V+ I ++ ++ ++ + FLG FG N Y
Sbjct 192 AIGLSIVVIGALIIIAYLTSRVDFALYLNIPNVKGCEELVIFLGALLGGSFGFL-WFNAY 250
>sp|P03586|RDRP_TMV Replicase large subunit OS=Tobacco mosaic
virus (strain vulgare) OX=12243 PE=1 SV=2
Length=1616
Score = 37.4 bits (85), Expect = 8.1, Method: Composition-based stats.
Identities = 68/406 (17%), Positives = 122/406 (30%), Gaps = 73/406 (18%)
Query 5595 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5654
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFDED---LILVPGKQAAEMIRRRA------NSS 872
Query 5655 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNAR 5714
I+ + V+ D F +N + DE M ++ + A
Sbjct 873 GIIVATKDNVKTVDSFMMNFGKST----------RCQFKRLFIDEGLMLHTGCVNFLVAM 922
Query 5715 LRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVD 5774
+ GD Q+P + G P +F + + T RCPA++
Sbjct 923 SLCEIAYVYGDTQQIPYINRV--SGFPYPAHFAKL-----EVDEVETRRTTLRCPADVTH 975
Query 5775 TVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5834
++ Y+ + + + G + S + + LT + ++A+
Sbjct 976 YLNRR-YEGFVMSTSSVKKSVSQEMVGGAAVINPISK------PLHGKILTFTQSDKEAL 1028
Query 5835 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC---NVNRFNVAITR 5891
Y+ TV QG Y V + T T S + VA++R
Sbjct 1029 LSRGYS------------DVHTVHEVQGETYSDVSLVRLTPTPVSIIAGDSPHVLVALSR 1076
Query 5892 AKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTH 5951
L++ ++ + E ++ D KV G
Sbjct 1077 HTCS-------------LKYYTVVMDPLVSIIRDLEKLSSYLLDMYKVDAG-----TQXQ 1118
Query 5952 LSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
L +D+ FK L V P IS M F + + G M
Sbjct 1119 LQIDSVFKGSNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTM 1157
>sp|O93058|RDRP_TMVOM Replicase large subunit OS=Tobacco mosaic
virus (strain OM) OX=12251 PE=3 SV=1
Length=1616
Score = 37.4 bits (85), Expect = 8.3, Method: Composition-based stats.
Identities = 68/406 (17%), Positives = 122/406 (30%), Gaps = 73/406 (18%)
Query 5595 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5654
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFDED---LILVPGKQAAEMIRRRA------NSS 872
Query 5655 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNAR 5714
I+ + V+ D F +N + DE M ++ + A
Sbjct 873 GIIVATKDNVKTVDSFMMNFGKST----------RCQFKRLFIDEGLMLHTGCVNFLVAM 922
Query 5715 LRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVD 5774
+ GD Q+P + G P +F + + T RCPA++
Sbjct 923 SLCEIAYVYGDTQQIPYINRV--SGFPYPAHFAKL-----EVDEVETRRTTLRCPADVTH 975
Query 5775 TVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5834
++ Y+ + + + G + S + + LT + ++A+
Sbjct 976 YLNRR-YEGFVMSTSSVKKSVSQEMVGGAAVINPISK------PLHGKILTFTQSDKEAL 1028
Query 5835 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC---NVNRFNVAITR 5891
Y+ TV QG Y V + T T S + VA++R
Sbjct 1029 LSRGYS------------DVHTVHEVQGETYSDVSLVRLTPTPVSIIAGDSPHVLVALSR 1076
Query 5892 AKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTH 5951
L++ ++ + E ++ D KV G
Sbjct 1077 HTCS-------------LKYYTVVMDPLVSIIRDLEKLSSYLLDMYKVDAG-----TQXQ 1118
Query 5952 LSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5997
L +D+ FK L V P IS M F + + G M
Sbjct 1119 LQIDSVFKGSNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTM 1157
>sp|Q00167|VG78_ICHVA Putative zinc-binding protein ORF78 OS=Ictalurid
herpesvirus 1 (strain Auburn) OX=766178 GN=ORF78 PE=4
SV=1
Length=400
Score = 36.6 bits (83), Expect = 8.3, Method: Composition-based stats.
Identities = 20/94 (21%), Positives = 37/94 (39%), Gaps = 10/94 (11%)
Query 2935 DTNVLEGSVAYESLRPDTRYVLMDGSIIQF--PNTYL---EGSVRVVTTFD--SEYCRHG 2987
DT ++ G S+RPD+ + ++F P +G T C
Sbjct 32 DTGIVPGLRVESSVRPDSITNFRRLAAVKFKNPEVMECGGKGGCEECKTRPALMLNC--- 88
Query 2988 TCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGV 3021
C+ ++ +C+ R V ++ +R+ V CG
Sbjct 89 DCDTAKVPICLGCKPRAVRDHPCFRNRTCVSCGT 122
>sp|Q9M6N7|AMT2_ARATH Ammonium transporter 2 OS=Arabidopsis thaliana
OX=3702 GN=AMT2 PE=1 SV=2
Length=475
Score = 37.0 bits (84), Expect = 8.4, Method: Composition-based stats.
Identities = 24/148 (16%), Positives = 46/148 (31%), Gaps = 17/148 (11%)
Query 3020 GVDAVNLLTNMFTPLIQPIGALDISASIV---------AGGIVAIVVTCLAYYFMRFRRA 3070
G +A L L G + + ASIV + A L + + ++ A
Sbjct 19 GDNAWQLTAATLVGLQSMPGLVILYASIVKKKWAVNSAFMALYAFAAVLLCWVLLCYKMA 78
Query 3071 FG-EYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLT-NDVSFLAHIQW 3128
FG E F + S + Y + + F T ++ +
Sbjct 79 FGEELLPFWGKGGPAFDQGYLKGQAKIPNSNVAAPYFPMATLVYFQFTFAAITTILVAGS 138
Query 3129 MV------MFTPLVPFWITIAYIICIST 3150
++ + VP W+ +Y + +
Sbjct 139 VLGRMNIKAWMAFVPLWLIFSYTVGAYS 166
>sp|D0E0C2|SCNA1_PERAM Sodium channel protein PaFPC1 OS=Periplaneta
americana OX=6978 PE=1 SV=1
Length=1553
Score = 37.4 bits (85), Expect = 8.5, Method: Composition-based stats.
Identities = 29/165 (18%), Positives = 55/165 (33%), Gaps = 5/165 (3%)
Query 3545 LGSALLEDEFTPFDVVRQCSGVTFQSA-VKRTIKGTHHWLLLTILTSLLVLVQSTQWSLF 3603
L S LED F PF ++ V ++ + R W+L V + + +F
Sbjct 84 LASTPLED-FDPFYKNKKTFVVVTKAGDIFRFSGEKSLWMLDPFTPIRRVAISTMVQPIF 142
Query 3604 FFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRI 3663
+ I + + FL ++ + + V + P +++
Sbjct 143 SY--FIMITILIHCIFMIMPATQTTYILELVFLSIYTIEVVVKVLARGFILHPFAYLRDP 200
Query 3664 MTWLDMVDTSLSGFK-LKDCVMYASAVVLLILMTARTVYDDGARR 3707
WLD + T + + D + +L + RTV R
Sbjct 201 WNWLDFLVTLIGYITLVVDLGHLYALRAFRVLRSWRTVTIVPGWR 245
>sp|A8F0C9|ATP6_RICM5 ATP synthase subunit a OS=Rickettsia massiliae
(strain Mtu5) OX=416276 GN=atpB PE=3 SV=2
Length=242
Score = 36.2 bits (82), Expect = 9.5, Method: Composition-based stats.
Identities = 24/148 (16%), Positives = 49/148 (33%), Gaps = 11/148 (7%)
Query 3583 LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMM-FVKHKHAFLCLF-- 3639
L+ ++ +L F + + F + I+ ++ FVKH FL LF
Sbjct 87 LVFSLFIFILFCNLLGMTPYSFTTTSHIIVTFTLAILVFLTVTIVGFVKHGLRFLTLFLP 146
Query 3640 ------LLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLI 3693
L P + + F + P S +R+ + L + L I
Sbjct 147 HGTPLWLAPLMIVIELFTYLARPVSLSLRLAANMMAGHVLLKVIAGFTVSLMIYLKFLPI 206
Query 3694 LMTARTVYDDGARRVW--TLMNVLTLVY 3719
+ + + + + +L+ +Y
Sbjct 207 PLMMILIGFEIFVAILQAYIFTILSCMY 234
>sp|P54334|XKDO_BACSU Phage-like element PBSX protein XkdO OS=Bacillus
subtilis (strain 168) OX=224308 GN=xkdO PE=4 SV=2
Length=1332
Score = 37.0 bits (84), Expect = 9.5, Method: Composition-based stats.
Identities = 19/96 (20%), Positives = 38/96 (40%), Gaps = 3/96 (3%)
Query 592 TNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKF 651
T I+G +++ ++ N++ V E + W+ K + + + W
Sbjct 595 TGLCNAWTVISGIWSTVSTWFMDNVWNPVSEAVTTAATWIWSKINDAWTIISNIWTG--- 651
Query 652 ISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLA 687
+S + V IV ++IK S++ F KF
Sbjct 652 VSNWFYDNVWNPIVKKVEDIKTSIKEKFDDARKFFE 687
>sp|Q6Q487|CALX_ASPFU Calnexin homolog OS=Aspergillus fumigatus
(strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) OX=330879
GN=AFUA_4G12850 PE=2 SV=2
Length=563
Score = 36.6 bits (83), Expect = 10.0, Method: Composition-based stats.
Identities = 20/107 (19%), Positives = 37/107 (35%), Gaps = 3/107 (3%)
Query 911 SGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEF--GATSAA 968
GE + F PP E+E D +++ E D KP ++ A
Sbjct 230 DGEAVKNGTLLEDFAPPVNPEKEIDDPKDKKPADWVDEAKIPDPEAKKPDDWDEDAPYEI 289
Query 969 LQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEME 1015
+ E EDWL+D+ ++ + + + + P +
Sbjct 290 VDEEATMPEDWLEDEPT-SIPDPEAEKPEDWDDEEDGDWIPPTVPNP 335
Lambda K H a alpha
0.318 0.133 0.375 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0408 0.140 1.90 42.6 43.6
Effective search space used: 873118871808
Database: uniprot_sprot.fasta
Posted date: Apr 3, 2024 12:05 PM
Number of letters in database: 206,678,396
Number of sequences in database: 571,282
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40